PharMolix/UniProtQA huggingface dataset:
Protein: COBQ_PARP8
Sequence: MIQGTTSDAGKSTLVAGLCRLARRAGVRVAPFKPQNMALNSAVTIDGGEIGRAQALQAVAAGIDAHTDLNPVLLKPTSDRGAQVIIHGKARMNLDARAYHDYKPVAFEAVLASYARLKASYDTIFVEGAGSPAEINLRERDIANMGFAEAVDCPVVLVSDIDRGGVFAHLTGTLACLSDSEQARVRGFVINRFRGDVSLLQPGLDWLEAKTGKPVLGVVPYLHGLTLDAEDMLPRELRAAQASADALRVVVPALPHISNHTDFDALRAHPQVDFHYVRAGSAPPPADLIILPGSKNVQGDLAFLRAQGWDAVLQRHLRYGGRVIGICGGMQMLGREVADPYGVEGPPGTVEGLGWLDFSTTLTRDKTLKNVTGRLATDAGRIAGYEIHMGETQGPALDAPALLLADEMGGVRPDGARSADGQILATYVHGLFDTPAACASLLAWAGLKNADAIDYPALREASLERLADTLAVHLDLKRFWEAIG
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: CD180_HUMAN
Sequence: MAFDVSCFFWVVLFSAGCKVITSWDQMCIEKEANKTYNCENLGLSEIPDTLPNTTEFLEFSFNFLPTIHNRTFSRLMNLTFLDLTRCQINWIHEDTFQSHHQLSTLVLTGNPLIFMAETSLNGPKSLKHLFLIQTGISNLEFIPVHNLENLESLYLGSNHISSIKFPKDFPARNLKVLDFQNNAIHYISREDMRSLEQAINLSLNFNGNNVKGIELGAFDSTIFQSLNFGGTPNLSVIFNGLQNSTTQSLWLGTFEDIDDEDISSAMLKGLCEMSVESLNLQEHRFSDISSTTFQCFTQLQELDLTATHLKGLPSGMKGLNLLKKLVLSVNHFDQLCQISAANFPSLTHLYIRGNVKKLHLGVGCLEKLGNLQTLDLSHNDIEASDCCSLQLKNLSHLQTLNLSHNEPLGLQSQAFKECPQLELLDLAFTRLHINAPQSPFQNLHFLQVLNLTYCFLDTSNQHLLAGLPVLRHLNLKGNHFQDGTITKTNLLQTVGSLEVLILSSCGLLSIDQQAFHSLGKMSHVDLSHNSLTCDSIDSLSHLKGIYLNLAANSINIISPRLLPILSQQSTINLSHNPLDCTCSNIHFLTWYKENLHKLEGSEETTCANPPSLRGVKLSDVKLSCGITAIGIFFLIVFLLLLAILLFFAVKYLLRWKYQHI
What is the function of this protein?
May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells.  Leads to NF-kappa-B activation.  Also involved in the life/death decision of B-cells (By similarity).
What are the official names of this protein?
CD180 antigen, Lymphocyte antigen 64, Radioprotective 105 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CYSD_YERPE
Sequence: MDEKRLTHLRQLEAESIHIIREVAAEFGNPVMLYSIGKDSSVMLHLARKAFFPGHLPFPLLHVDTGWKFREMYEFRDHTVKEFGCELLVHRNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTELDIWQYIFLEKIEIVPLYLAKPRPVVERDGMLLMVDDDRIDLQPGEVIVQKKVRFRTLGCWPLTGAVESEAETLPAIIEEMLISTTSERQGRMIDRDQSGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RL24_CLOB8
Sequence: MKIHVRKNDTVIVISGKDKGKTGEVLKAYPKTGKVLVQGVNIVKKHQKANKGQVESAIIEKEAAINSSKVMLYCNKCKNATRISNKVLDDGTKVRVCKKCGETF
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: Y520_BACC1
Sequence: MDLSVKSEENVEYMVEAIKEKLRMVNAGAMRAASFNEEMYEDLRDIYEHVMKRETFSISEMQAITEELGTLIKK
What are the official names of this protein?
UPF0435 protein BCE_0520.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: KHSE_CORGL
Sequence: MAIELNVGRKVTVTVPGSSANLGPGFDTLGLALSVYDTVEVEIIPSGLEVEVFGEGQGEVPLDGSHLVVKAIRAGLKAADAEVPGLRVVCHNNIPQSRGLGSSAAAAVAGVAAANGLADFPLTQEQIVQLSSAFEGHPDNAAASVLGGAVVSWTNLSIDGKSQPQYAAVPLEVQDNIRATALVPNFHASTEAVRRVLPTEVTHIDARFNVSRVAVMIVALQQRPDLLWEGTRDRLHQPYRAEVLPITSEWVNRLRNRGYAAYLSGAGPTAMVLSTEPIPDKVLEDARESGIKVLELEVAGPVKVEVNQP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_HAES1
Sequence: MTIFAKDKLIAYGQLMRLDKPIGTLLLLWPTLWALYLAEKAMPTLSVLAIFICGVFLMRSAGCVINDYADRHIDGKVKRTSLRPLSTGRATPREAKWLFIVLVFCSFLLVLCLNLYTIGLSVIAVILAFIYPFMKRYTHLPQFFLGAAFGWSIPMAYGATIEALPLECWLLFIANLSWTVAYDTQYAMVDRDDDLRIGVKSTAILFAQYDNKIIALLQIITLIFLFSVGYLSQLNNRYFIVLAIAGLFFVYQCRLTKNRDRASCFNAFLNNNYFGLTVFIAVLFGI
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLY1_DROVI
Sequence: MLTLRERQINAIKQMLNLNSQQPKAMAADAVWKILIYDRVGQDIISPIISIKELRELGVTLHVQLHSDRDSIPDVPAVYFCLPTDENLDRIQQDFSNGLYDIYHLNFLAPITRSKIENLAAAALHAGCVANIHRVYDQYVNFISLEDDFFILKHQQSDQLSYYAINRANTRDEEMEALMDSIVDSLFALFVTLGNVPIIRCPRNSAAEMVARKLEKKLRENLWDARANLFHMDATQAGGGVFSFQRPVLLLLDRNMDLATPLHHTWSYQALVHDVLDLGLNLVYVEDEGARKKPKACDLDRNDRFWVTHKGSPFPTVAEAIQEELESYRNSEEEIKRLKTSMGIEGESDIAFSLVNDTTAMLTSAVNSLPQLMEKKRLIDMHTKIATAILNCIKARRLDSYFEIEEKIMSKQTLDKPLLELLRDAEFGQPEDKLRLYIIYYICAQQLPEPELERLREALQSAGCDLTALAYVQRWKSIMNRSPSISQATQYEGGGTRTVSMFTKLVSQGSSFVMEGVKNLVVKRHVNINLRLGSDRVKAKLIPNFLENLPVTKITEQVMECRSNAETDDYLYLAPKLLKGGDVLPKNRAPFQDAVVFMVGGGNYIEYQNLVDFIKQKQTSNVHRRIIYGGSTLTNARQFLKELSALGGEIQTPTAS
What is the function of this protein?
Non-vital for development.
What are the official names of this protein?
Protein sly1 homolog.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: RRF_AQUAE
Sequence: MIKELEDIFKEAEKDMKKAVEYYKNEIAGLRTSRASTALVEEIKVEYYGSKVPIKQLGTISVPEHNQIVIQVWDQNAVPAIEKAIREELNLNPTVQGNVIRVTLPPLTEERRRELVRLLHKITEEARVRVRNVRREAKEMIEELEGISEDEKKRALERLQKLTDKYIDEINKLMEAKEKEIMSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_LEPIN
Sequence: MIEIQFYNSLSGRKEKFSPSDPNRVTVYSCGPTVYNFAHIGNLRAFLFVDVLRRSLKLLGYGVDMTMNITDIDDKIIRDSIASKKSIIEFTAPWTKAFFEDLKTVSAEILEHYPKATDSIPEMVDIIQKLQKKGLVYKKDESLYFSIQKFQNYGKLSKIDTSGMKTGTRYDTDEYEKEDVRDFVLWKSPKLEGETSWDTLVGTGRPGWHLECSAMIRKVYGSGVDIHTGGVDLLFPHHENEIAQSEGAFPEESFVKTWLHSEHLLVDGQKMSKSKGNFYTLRDLIQQGLDPKAIRFLLISTHYRSKLNFSTDRIAEASANIRKIQNCLDRILELEPDIKADFYFLFSIPFVQTWKKEFEESLADDLNISKALAVVFESVKQINSLLDTNQSDSKQRIEYIQILAYFDRILGVLNFESKKDLLDSEIDSLIEERQIARKNKDFARSDAIRDQLLAQGILIEDTKEGIRWRKK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA4_HUMAN
Sequence: MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit alpha type-4, Macropain subunit C9, Multicatalytic endopeptidase complex subunit C9, Proteasome component C9, Proteasome subunit L.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
Protein: RNH_NITEC
Sequence: MQLKSDMKRVEIFTDGACKGNPGPGGWGVCLHFNGETREFFGGEPVTTNNRMELLAAIRALQELESLEDNGQQHLQVQLHTDSQYVQKGISEWIHGWKKRGWRTADKKPVKNEALWRELDDLSQRHQVEWFWVRGHNGHAGNERADRLANQGVESVLSKKAD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC3_BOVIN
Sequence: MGAVLGVFSLASWVPCLCGGASCLLCSCCPNSKNSTLTRLIYAFILFLGTIVCCIMFHEGMETQLKKIPGFCDEGLSTRITDIMDKECDVLVRYKAVYRISFALAVFFFAFSLLMLNVKTSKDPRAAIHNGFWFFKIAAIVGVMVGSFYIPGGHFNTAWFVIGMVGAAFFILIQLVLLVDFAHSWNESWVNRMEEGNPKCWYAALLSVTSLFYILSIIFAGLLYTYYTKPDGCTENKFFISFNLILCVVISVLSIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPDRSCNPGLLSIITHMTSSTLAPANTTAPAPTPAVPLQSGPSLNKENFIGLLVFVLSLSYSSIRNSSNSQVSKLTLSGSDSVILRDTAANGASDEEDGRPRRAVDNEREGVQYNYSMFHLMLCSASLYIMMTLTNWYSPDANFQSMTSKWPAVWVKISSSWVCLLLYVWTLVAPLVLTNRDFS
What is the function of this protein?
Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm.
What are the official names of this protein?
Serine incorporator 3.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Localizes to the cell membrane, where it is efficiently incorporated into budding gammaretrovirus virions and impairs subsequent virion penetration of susceptible target cells (By similarity).
Protein: CMOB_ECO5E
Sequence: MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSNAVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVSVTTTEEQRRTEWMVTESLSDFLDPHDPSKTVEGYPAPKRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: HYLS1_CAEEL
Sequence: MANFTTENELEDILHQMGHHIHDKNQFATFKNEIDNLLDRELCLSDADEDVMNESLFASLSVDPAAQFIRQERNFPTENLNIQSPIVSRKRQGKRFIYENVELQSDFDDESSNEYPERNLLVDRAWRSIHRAMETCNGATETLKSISLDGSDIQERSSVDDEENIAESVSVGLSTETEQSELQKSSRPEKEVWTRNVLSLEPGRAPKKYDPVTRYHFYKSEWDRHPAPGEMRRLSLRWKVREFMLRHDVPRLNENNEDWKANHDKDWSPRPYID
What is the function of this protein?
Plays an important role in ciliogenesis (PubMed:19656802).
What are the official names of this protein?
Centriolar and ciliogenesis-associated protein hyls-1, Hydrolethalus syndrome protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HYLS1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Note=Colocalizes with sas-4 to centrioles throughout the embryonic cell cycle and in sperm (PubMed:19656802). Localizes at the base of mature cilia(PubMed:19656802).
Protein: CF97D_HUMAN
Sequence: MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYVSHKNRIQIAKPTVDTKPPVAHTNHILKLSKLQGEQKKINKIEYENKQLCQKIANAHRGPAKVDCWNEYFSKSLNRETRNRELVRITMENQGILKRLVDRKPHYDRRASEIDWQNSRRYIRNTTRYLLSQNE
What is the function of this protein?
Required for male fertility through its role in axonemal doublet stabilization which is essential for sperm motility and fertilization.
What are the official names of this protein?
Sperm axonemal maintenance protein CFAP97D1, CFAP97 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CFAP97 family.
Protein: ZBT32_MOUSE
Sequence: MPQTPTRLVSPYGSDRLVQLAARLRPALCDTLITVGGLEFPAHSLVLAGASPRLGCRGRWALVEDISPSTFAQILTFVYGESIELQPGELGDLEEAAKALGVQALEEACQRAQKGKDEDELDPGLKRHQQSEDFMRGSERGLGSPGEKQKPEKDFRSNGREQEMSHKHKAPGERPEMAGATRMMSSEEVMRGIESHKGSEESLRGCPDPLSPPGSLLTSLIPRPWWAEVPRLGEGQSALWSILLWPSRYGAPFSHSTPITAAWQVRPQDQRIPLTLNHSKALWSQNQLASSSPTPGSFPQGTESLSPWQIETSGQGFTGTLATCVSQERTLNCPSHQHPPLPSPARSRPYSCSVCGKRFSLKHQMETHYRVHTGEKPFSCSLCPQRSRDFSAMTKHLRTHGAAPYRCPLCRAGCPSLASMQAHMRGHSPSRLPPGWTIRSTFLYSSSRPTRASSSPGSPTSSAAT
What is the function of this protein?
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence.  May function as a transcriptional transactivator and transcriptional repressor (By similarity).  Probably exerts its repressor effect by preventing GATA3 from binding to DNA.  May play a role in regulating the differentiation and activation of helper T-cells.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 32, Repressor of GATA, Testis zinc finger protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Located in nuclear speckles.
Protein: RPOA_SYNFM
Sequence: MQRNWRELIKPKRLEVETKGLPNTYGKFECEPLERGFGITLGNALRRVLLSSLQGAAITSVKVDGVLHEFSTIPGVLEDVTDVILNLKEVRFKMHSDGPRLVVIEKDGEGEVAAGDIQGGPHVEVLNPEQHICTLEKDARLRMELTVKQGKGYLPADRNIEENQPIGTIPIDAIFSPIRKVSYTVTQARVAQITDYDKLTMEIWSDGSVKPDDALAYSAKILKDQLTIFINFEEEMETTEEEVRAEPVFNDHLFRSVDELELSVRSANCLKNADIRYIGELVQKTEAEMLKTKNFGRKSLNEIKEILTEMGLSLGMKLENFPSRDDIENRRKEQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: GRLJ_DICDI
Sequence: MKILLYIAIILSFFSLITISSECKIAVLLSGSPNDLGYNYLMNEARVKAESELKLDFSIYYENLEESMEEAEKAFQDALHKGANLIVVGSFVHVGLGLKYAALTKDQDIYWIIRGNKRPNPDLPHVVILNFNSFELHYLLGYFSGLMTKTGIVGFVAPGPDVNTISTDNSFYLGAKYARPNITFLNVYVQSWYNPNVSYSAAKMLIKNGADLIGMSQDDMSCQKAMMDSGLIGIGATGYPTHLLFGGNVGVSYITNWTNLYVKYAQHVLNDDWPDYSSYFTNLSREDSIFIDDYSYKVPIDIQNLVNDEIQRLKNTSYIPYRSDPYLAQLGIPFDSKGLLVEDQFRANKKLLKGDSISKVIDFGQYSIPIEFIDYPNSLKYGVTIVSGVCIFICLVCMTLVVVFKKARVIKSSSPAFLLLILLGCCIIFAACILFAQSPTNQTCSARIWLLSLGYTLFLGNLLVKNWRIWLLFDNPKLKKRAITNWKLYPWVFAILAIDVMILAIWQGLGNINAESRIGYDSLTQYQYKNVCSSDDQGSIALYLLLVFHGLVLLVACFISFKIKVVDIEEFNESKPITTSVYIITFCLFIVIPLMVSPQSLTSQTTIICVCAIVTTLISMLLLFGSKFYKMATQGLAINETFATSTKSSSKSSKSSYGKDNPNPNAINFGEDDTSDETSEEKHKSPKQKSVNFSNKSNSHLAVFTSDEETSKTSKLSIDFENSSKDISIDQLQQQKQQPINTNGDLENKSNDKIDDDNDNSSVLSKRISNQQNGETEIDSNNV
What is the function of this protein?
May act during the development and be a negative regulator.
What are the official names of this protein?
Metabotropic glutamate receptor-like protein J.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane. Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Golgi apparatus membrane. Nucleus envelope. Note=May also localize to internal membranes.
Protein: RHAT_SALPK
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKQVKQWSWETMWSVGGIVSWLILPWTISALLLPDFWAYYGQFNLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLIHTEGGRMTLLGVFVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLLLAVICGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGALVNLGFCFIRLAKVQNLSIKADFSLARPLIISNILLSALGGLMWYLQFFFYAWGHARIPAQYDYMSWMLHMSFYVLCGGLVGLVLKEWKNAGRRPVAVLSLGCVVIIIAANIVGLGMAS
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOH_SALAR
Sequence: MSWITPDLIEILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWVPKFSDRVIFTLAPMIAFTSLLLSFAIVPVSPNWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTVSYEVFLGLSLMGVVAQAGSFNMTDIVNNQAHLWNVIPQFFGFVTFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTVSALMVTLFFGGWHGPFLPPFVWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKVCLPLTLINLLVTAAVILWQAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYL_MYCTU
Sequence: MTESPTAGPGGVPRADDADSDVPRYRYTAELAARLERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRRSFSTTDVDFYRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKLTAGERADVIDEYRLVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAASWPAGVNPLWTYGGGTPGEAIAAYRRAIAAKSDLERQESREKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFDPDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPGGVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYVPAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTTSLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGATPRKVIVVAGRLVNLVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_SPOFR
Sequence: MARVPPPALKKDKKEKKPPKDNSKNVMRNLHIRKLCLNICVGESGDRLTRAAKVLEQLTGQQPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILERGLKVREYELRRDNFSATGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGPTRIQCTTQKTQDWQGWIPPIVLTKEDAMKWFQQKYDGIILNSKK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ATPB_PROM4
Sequence: MAPAATASTGTKGIVRQVIGPVLDVEFPAGKLPKILNALRIEGKNPAGQDIGLTAEVQQLLGDHRVRAVAMSGTDGLVRGMEAVDTGAPISVPVGEATLGRIFNVLGEPVDEQGPIKSSTTSPIHRSAPKLTDLETKPKVFETGIKVIDLLAPYRQGGKVGLFGGAGVGKTVLIQELINNIAKEHGGVSVFGGVGERTREGNDLYEEFKESGVINADNLTESKVALCFGQMNEPPGARMRVGLSALTMAEHFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTDVGELQERITSTLEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLARALAAKGIYPAVDPLDSTSTMLQPAVVGDEHYRTARAVQSTLQRYKELQDIIAILGLDELSEEDRKTFDRARKIEKFLSQPFFVAEIFTGMSGKYVKLEETIAGFNMILSGELDNLPEQAFYLVGNIEEVKAKAQKINSENKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: KDSA_SHIF8
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LBD35_ARATH
Sequence: MNSTCCSACKVMKCDCAPNCIFAPHFPLTNLETFERLHRIFGAGNVFKILANLDPIQRETAVNALCYEAEALERDPIFGCVGIFNHYKNQLQNLDEQINSAKNELAAIIGLDNVPQYSSIPMPADFLTNKFSLHPYIEKMEGLDEVQKKELMQLPPVDAQVIVNEMFRKRGNIKICGGHGDACASTSGGTSATQKTLPFPQNHNQP
What are the official names of this protein?
LOB domain-containing protein 35, ASYMMETRIC LEAVES 2-like protein 27, AS2-like protein 27.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.