PharMolix/UniProtQA huggingface dataset:
Protein: EIF3A_CAEBR
Sequence: MAPNYFQKPEAALKRAEELIQVGKESDALDTLHDTIKARRHKQWTTVHEQIMIKHMELCVDLKKQHLAKDALFQYKALTQQINVKSLETVVEHFLKLAEQRTEDAQKQSIEKVEEIGDLDQGDVPERLLLAVVSGAAAQDRMDRTVLAPWLRFLWDSYRNCLELLRNNAQVEQLYHTISRHSFSFCLRYQRRTEFRKLCDLLRMHLNQIQKHQYAPNVNSFRVKLTSPESLTLMQDTRLVQLDTAIQMELWQEAYKSAEDVHGMMQLSKDKDKRTVKPSSYVNYYDKLALVFWKAGNRLFHAAALLQKFIIYKDMKKSFTQEEAQEQATRVLLATLSIPEGSDLPSDLSRNLDIEEQHVANMRLLSNLLRLPIAPTKVGILKEAARIGVPEAAGQVAKDLFKLLESNFSPLRVAKDVQSVLDTITRPDHLQYVESLQAVAAVKALKQVSVIYEAISWERIRKIIPFYHDLALERLVVEASKHRIVKAQLDHRADCVRFGSSDATLAGGVDEYDNNEGFTGDDTQLGVEGVRNHLEAMYTRLRVLVEGLDSEKRRKEIVKKIENHVTSYEKNRVTEIERIHRRKKMLENYKENWERVKAEKAATAATEQAKREEAARAEEMKRLDEQNKESERKRKQAEQEEIQKKIKRDQLHKMQQNVIYQAIIKEKGLEQFRDMDPEQVLREQRERLDKERAETQRRLQQQEKKFDHHIRALHLEEMNERRAVMHMRLNEAPRLHEEYENKRIEKEIAAHENHVKLWSMWDQVREATLDWVETVKVENQENLEKKISDWEVKLEAVRNSRLAERAEKRKKERKEAAMQAKIAEERKRREEEERARQAVIDSQRRPHGERGQRREMENSAAMQDSDWRRNAPPRDSMPQREPRPMRDGPPREPFREMPSSKADTDSSWRSSAQPTRKPDDRRSDDFRRDDGPRRSDDHRRNDEFRRSDDFRRNDDFRRDGPPRPMSKADTDQKWERGAVTKTVVSPPKTENQPAPAAEAPKADGPRRFIPPALRNKPAGGGDEQPAPQRGANVTSPPDRAPGLRGPPGPGGRDLPPRDLPPRDGPRDIPRRDGPRRDGPNRNSGANNAGNADSANWRR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Egg-laying defective protein 45, Eukaryotic translation initiation factor 3 subunit 10.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_ERYLH
Sequence: MAKIKIKQTGSPIRRPESQKKILVGLGLNKMHKVVELEDTPEVRGAIAKIPHLVEVVD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PV22_POMMA
Sequence: MVKKIHFVMERHASIVAFLLAVLALTESQAFTSVKLPRDEHWPYNYVSVGPAGVWAVNRQNKLFYRTGTYGDNANMGSGWQFKQDGVGQVDVGKDKVGYINLSGGSLFRIEGISQANPVGGTPKSWEWWTKYIGMSLREDTRFSSRIENQNKVLTFTFRTCFWASRITNWCFADSSYTETVTAGGSGTWITKSQLKYKSGTFGNPDTEGGDWILVDSGSFQHVSSGSGVVLAVRSNGELVQRTGITCSLPQGTGWTSMLNSMSRVDTYGTVAWAVDTAGDLYFINL
What is the function of this protein?
The egg defensive protein perivitellin-2 is a pore-forming two-subunit glycoprotein that affects both the nervous and digestive systems of mammals (PubMed:32231667, PubMed:32446810).  In addition, it is a source of both structural and energetic molecules during embryonic development (By similarity).  The tachylectin subunit (31 kDa) binds target membranes while the MACPF subunit (67 kDa) disrupts lipid bilayers forming large pores (inner diameter of about 5. 6 nm) altering the plasma membrance conductance (PubMed:32446810).  Both in vivo and in vitro, the protein shows wide pH range stability and is resistant to enzymatic proteolysis from gastrointestinal environments (PubMed:32231667).  It is cytotoxic to both epithelial and immune cells from the digestive system of mammals (PubMed:32231667).  It induces enterocyte death by a lytic mechanism and disrupts enterocyte monolayers in a dose-dependent manner (PubMed:32231667).  After oral administration to mice, it binds enterocytes and induces large dose-dependent morphological changes on their small intestine mucosa, reducing the absorptive surface (PubMed:32231667).  Additionally, it is detected in the Peyer's patches where it activates lymphoid follicles and triggers apoptosis (PubMed:32231667).  The toxin can also traverse the intestinal barrier and induce oral adaptive immunity with evidence of circulating antibody response (PubMed:32231667).  The toxin also shows hemagglutination properties thanks to the tachylectin subunit, but has no hemolytic activity (PubMed:32446810).  In addition to enterotoxin activity, the toxin also acts as a neurotoxin, since an intraperitoneal injection can induce paralysis of the mice rear limbs, followed by death (PubMed:32446810).
What are the official names of this protein?
Perivitellin-2 31 kDa subunit, PmPV2 31 kDa subunit, PmPV2-31, PV2 tachylectin 'B' delivery subunit, Pma_3499_0.54, Pore forming toxin, PFT.
What is the protein family that this protein belongs to?
Belongs to the tectonin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: PYRE_BACFN
Sequence: MKNLERLFAEKLLKIKAIKLQPANPFTWASGWKSPFYCDNRKTLSYPSLRSFVKFEITRLVLERFGQVDAIAGVATGAIPQGALVADALNLPFVYVRSTPKDHGLENLIEGELRPGMKVVVVEDLISTGGSSLKAVEAIRRDGCEVIGMVAAYTYGFPVAEQAFKDAKVPLVTLTNYEAVLDVALRTGYIEEEDIATLNEWRKDPAHWETGK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PP128_ARATH
Sequence: MFFSGLISKLHVHGTKRTNHFTIFHRLNHFVTTSSSSVTPLSPQDRNKLLATLLSNCTSLARVRRIHGDIFRSRILDQYPIAFLWNNIMRSYIRHESPLDAIQVYLGMVRSTVLPDRYSLPIVIKAAVQIHDFTLGKELHSVAVRLGFVGDEFCESGFITLYCKAGEFENARKVFDENPERKLGSWNAIIGGLNHAGRANEAVEMFVDMKRSGLEPDDFTMVSVTASCGGLGDLSLAFQLHKCVLQAKTEEKSDIMMLNSLIDMYGKCGRMDLASHIFEEMRQRNVVSWSSMIVGYAANGNTLEALECFRQMREFGVRPNKITFVGVLSACVHGGLVEEGKTYFAMMKSEFELEPGLSHYGCIVDLLSRDGQLKEAKKVVEEMPMKPNVMVWGCLMGGCEKFGDVEMAEWVAPYMVELEPWNDGVYVVLANVYALRGMWKDVERVRKLMKTKKVAKIPAYSYASTTF
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g77170, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IHFB_JANSC
Sequence: MIRSELIQKLSDENPHLYQRDVERIVNSIFEEVIDALAAGDRVELRGFGAFSVKKRDARIGRNPRTGESVSVEEKHVPFFKAGKLLRDRLNGHES
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CHH_JASLA
Sequence: AVFDQSCKGVYDRSLFSKLDRVCDDCYNLYRKHYVATGCRRNCYGNLVFRQCLDDLMLVDVVDEYYVASVQMV
What is the function of this protein?
Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level.  Has a secretagogue action over the amylase released from the midgut gland.  May act as a stress hormone and may be involved in the control of molting and reproduction.
What are the official names of this protein?
Crustacean hyperglycemic hormone, CHH, JAL-CHH-I.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOB_SYNFM
Sequence: MPTALTHEYRVRKNFGKIHKIIDIPNLIQMQKESYELFLQRDVPSEARSERGLQEVFKSVFPIEDFSGTASLEFVQYSFGEVKYEVEECLARGMTYEAPVKIVVRLVVYDVDKEAGTRSIRDIKEQEIYFGTLPLMTDNGTFIINGTERVIVSQLHRSPGIFFDHDRGKTHSSGKILYSARIIPLRGSWLDLEFDPKDILYIRIDRRRKFPVTVLLKALGYATEELLNYFYPSEKIFLKSEAQSEKELNPDILMGSRAPEDILHPQTGEVLIKKNRKLGKQALRRLQEVGINRLPMKSTELIGQVLAQDVIDYGTGEIVAECNDSIDADMLKEFVERGVGEIELLHLEGQDVSPSFRNTLLMDKVNTQEDALIEIYRRLRPSNPPTLEVATEFFNNLFFNPDHYDLSEVGRLKLNLQLGLEVPLDYRTLRKDDILMAVRQLIRLKDSQGPVDDIDNLGNRRVRAVGELLENQYRIGLVRMERAIKERMTLQEVEALMPHDLINAKPVSAVVKEFFGTSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLIVSLSTYARVNPYGFIETPYRKVDGSSARKDVSYLTAMDEKEYPIAQANAPLDEKGRFLLDLVSARVAGEPVMVPPNEIRYMDVSPNQLVSVSASLIPFLEHDDANRALMGSNMQRQAVPLIQTRAPLVGTGIERIVAKDSGVAIVARRTGVVEYVDATRIVIRAIEDNGEMGSGVDIYKLIKFQRSNQNTCINQKPLVQHGDLVTKGQIIADGPSTDHGELALGRNVMVAFMSWGGYNFEDSILVSERIGKEDVFTSIHIEEFEVVARDTKLGKEDITRDIPNVGEEALKNLDESGIIRVGAYIKPNDILVGKVTPKGESQLTPEEKLLRAIFGEKASDVKDTSLRVPPGVEGIIIDAKVFSRKGVEKDERTKTIEDQEISRLMKDQRDELEIIFKSTVKRLAKLLENQVSDSAIKDGKKVYIKKGEVFTEEILLNLPSGHWDQLTVAKDPTVSMEIENILANYREQVQLVKSLFEEKIGKLKRGDELPPGVIKMVKVYVAVKRKLQVGDKMAGRHGNKGVVSRILPAEDMPYFPDGTPVDIVLNPLGVPSRMNVGQVLETHIGWAAKGIGMQLAQMLEECRERETMNEKLQRIYNKLEFGTYFKDASERELRGLIPDFKEGIHVASPVFDGAEEAEIRAFLSEAGVSETGQSVLYDGRTGMPFDQPVTVGVMYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWTMEAYGAAYALQEFLTVKSDDVAGRTRMYEKIVKGDNTLEAGLPESFNVLVKELQALALDVRLLEEEEGN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: Y3773_RHILW
Sequence: MDEKLSRVDPKLLDLLVCPLSKGRLSYDREHNELVSEKARLAYPIRDGIPIMLVSEARRLDE
What are the official names of this protein?
UPF0434 protein Rleg2_3773.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PAM17_YARLI
Sequence: MSLQMLRSRVALARPTLVRPSVGQMTKRFAGTAPVPLTWERFLLLRTRRRQINFVASIFTGVATSVLAWGFISEAELDLEQQDVFFGLDAFTAAGLGVVAAGFMGSLLGPTIGQLIFKATNSKQWPAFLMKETDFLSHIQKNRVNPRYQSVSNPVPDYYGEKIGSLKDYRRWLRDCAKYNRAREV
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Presequence translocated-associated motor subunit PAM17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PAM17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: APOE_OCTDE
Sequence: MKVLCTVLVVTLLAGCRADVEPEPEVLEPAVWKSGQPWELALGRFWDYVRWVQTLSDQVQEELLSSQVTQELTVLMEDTMKAVKAYKSELEQELVPMAEDTKARLSKELQAAQARLGADMEEVRNRLAQYRNEMQAMLGQSADELRARLASHLRKLRKRMLRDAEDLQKRLAVYKDGASEGAERGVSAIRERLGSLVEQSRVRAALTGQPLQERAQAWGKQLRGRLEEVRGQAQDRLEEMREQMEEVRVKIEEQAEAFQTRLKGWFEPMVEDMRRQWADLIEKVQAAVGASTPVPSQKP
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: THIG_CUPMC
Sequence: MTFEPTETLRDPFVLYGESFASRLLLGTARYPSPATLQAAVEASRPAMITVALRRQTAVGSGDGQTLGGETFWQMLRTLGVPVLPNTAGCFTAQEVITTAMMAREVFETDWIKLELIGDDYTLQPDTLNMPAVAETLVKEGFKVLPYCTEDLVLCRRLLDVGCQALMPWAAPIGTGRGAVNPHAMRTLRDRLPDTPLIVDAGLGLPSHAAQVLEWGYDGVLLNTAVAQSAYPVNMARAFALAVEAGRTAYLAGPMPEREVAQASTPVVGMPFWHAEGAEDRA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_IDILO
Sequence: MTTTARVPILADSDAETVAVKAIAERWGLPFETTDNDVFQLWLTEGVLALHWLQSPQKMSPLVVDFHQGKAAYRAQNTQLKNEAIAKAVGVTGQFKPSVVDGTAGLGRDAFVLAGLGCNVQLIERHPVVAALLDNGLHRAQKEHDFIGDTCLRMQLIGTDNLFTGSGYTQEPDVVYLDPMYPKTGKQKAQVKKDMQMFQQLVGSDEDADTLLEPAIALAKYRVVVKRPNSAPFLAGREPNSQIKSKKHRFDVYIKRGFHESAN
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARM1_HUMAN
Sequence: MVYKTLFALCILTAGWRVQSLPTSAPLSVSLPTNIVPPTTIWTSSPQNTDADTASPSNGTHNNSVLPVTASAPTSLLPKNISIESREEEITSPGSNWEGTNTDPSPSGFSSTSGGVHLTTTLEEHSSGTPEAGVAATLSQSAAEPPTLISPQAPASSPSSLSTSPPEVFSASVTTNHSSTVTSTQPTGAPTAPESPTEESSSDHTPTSHATAEPVPQEKTPPTTVSGKVMCELIDMETTTTFPRVIMQEVEHALSSGSIAAITVTVIAVVLLVFGVAAYLKIRHSSYGRLLDDHDYGSWGNYNNPLYDDS
What is the function of this protein?
May regulate TLP1 expression and telomerase activity, thus enabling certain prostatic cells to resist apoptosis.
What are the official names of this protein?
Prostate androgen-regulated mucin-like protein 1, PARM-1.
What is the protein family that this protein belongs to?
Belongs to the PARM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein.
Protein: RIBA_CAMHC
Sequence: MNIEISNVAKLPSRFGMFKVQAFKEDEKEHLVIIKEPYKEPVNIRIHSECLTGDAIGSLKCDCRDQLEESLKFIEKNGGMVIYLRQEGRNIGLFNKINAYNLQDKGLDTIEANHQLGFKTDERTYEIVDFILKYYKIKSINLLTNNPKKLMGLHNVKVAARVPIIIKPNKFNEKYLQTKKNEMGHLLDDNKKA
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: THII_PSEPF
Sequence: MKLIVKVFPEITIKSRPVRTKFIRQLAKNIRTVLRDLDPAVVVNGVWDNLELETRVTDPKALKEMGERLTCMPGIAHFLQIDEYPLGDFDDITEKCKQHYGDALAGKIFSVRCKRAGKHAFSSMDVEKYVGSKLRRECGAAGIDLKQPEIEVRIEVRDKRLFVIHSQHNGIGGYPLGALEQTLVLMSGGFDSTVAAYQILRRGLMTHFCFFNLGGRAHELGVMEVAHFIWKKYGSSQRVLFVSVPFEEVLGEILGKVDDSHMGVVLKRMMLRAASSIAERLHIDALVTGEAISQVSSQTLPNLSVIDCVTDKLVLRPLIVAHKQDIIDTADQIGTGDFARHMPEYCGVISVNPKTAAKRGRVEHEEQEFDMAVLERALANARLVPIDRVIDELGQDLQIEEVSEALAGQIVIDIRHPDAAEDDPLELAGIEVQTMPFYAVNARFKELDPTRQYLLYCDKGVMSRLHAHHLLSEGHANVRVYRPS
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_CALS8
Sequence: MILKAYAKINLTLDVLSKRDDGYHEIRTIMQTVDLYDIINIEKIEEDSIIVTTSSENIPTDNKNHAYIAASLVKERFGVKEGVKIHIQKNIPISAGLAGGSTDAAAVLRGLNKLFGLNLSQNELIELGREIGADVPFCLVGGTALCEGIGEKVTKLKSAPKMNILIAKPEVYVSTQAVYEALDLSKVKKRPNTDAMIVAIEEGNIREIAKNLCNVLETVTVNQYPVINRVKDIMRNHNALGTVMTGSGPAVFGIFANKYDALKAADRLKVFIKEIILTTTCENEFFSNEE
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MUC24_MOUSE
Sequence: MSGSSRRLLWAATCLAVLCVSAAQPNITTLAPNVTEVPTTTTKVVPTTQMPTVLPETCASFNSCVSCVNATFTNNITCFWLHCQEANKTYCANEPLSNCSQVNRTDLCSVIPPTTPVPTNSTAKPTTRPSSPTPTPSVVTSAGTTNTTLTPTSQPERKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKERNYHTL
What is the function of this protein?
Sialomucin that may play a key role in hematopoiesis.  May be involved in cell adhesion (By similarity).  Promotes myogenesis by enhancing CXCR4-dependent cell motility.  Positively regulates myoblast migration and promotes myoblast fusion into myotubes.
What are the official names of this protein?
Sialomucin core protein 24, MUC-24, Endolyn, Multi-glycosylated core protein 24, MGC-24, MGC-24v.
What is the protein family that this protein belongs to?
Belongs to the CD164 family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.
Protein: CR24_RANCA
Sequence: GLVSSIGKALGGLLADVVKTKEQPA
What is the function of this protein?
Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes.  Each caerin displays a different antimicrobial specificity.
What are the official names of this protein?
Caerin-2.4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SFSA_CLOBA
Sequence: MIFEKKTHIVEFVRRPNRFQGYVIIDGKEELVHVPNTGRCKEILIPGCRALIREENGQNRKTRFSLIGAYKGKNLINIDSQIPNKVVEEALINKKINGLEKYTKICREKTFGNSRFDFKLEDPLNNEYYLEVKGVTLEENGLCRFPDAPTERGTKHLLELIEVKNNNIGAGVLFLVQLENVKSFSPNDDTDPKFAAALKKAKSSGVDIFVYKCSVSENHIELSQSVELKL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: SPB4_ASPOR
Sequence: MAPKPPAGTSSRAWDGVSPSLSEWVLEAVSSMGFTRMTPVQASAIPLFMAHKDVVVEAVTGSGKTLSFLIPIVEKLLRLEEPIKKHHVGAIIISPTRELASQIYHVLLSLLAFHPPSASVINPSEDDDVPRQKFPSSTLKVVPQLLLGGSTTPAEDLSKFLKQSPNLLVSTPGRLLELLSSPHVHCPQSSFEMLVLDEADRLLDLGFKETLQNIIRRLPKQRRTGLFSASISEAVDQIVRVGLRNPVKVMVKVKGTSGAQDKRTPASLQMTYLTTPTIHKFDALKHILHSVDPTPQKTIFFASTCSGVDYLSAILPLILGDDFQLISLHGKHPANVREKNFNRFVNSYSPAILLTTDVASRGLDIPSVDLVVQIDPPSDPKTFIHRCGRAGRAGRRGLSVVLLHPGREEDYVSFLEVRKTPVAPFPHPISFSESEATAATKAVRKAVLADRALHDRGQKAFVSWLRSYSKHQASSIFRVADLDWESLGKAWGLLKLPKMPELRNFTGDRTLGVNLDWDDYKYKDKQREKRRIELLQESKEGDGTQESSNKRKATETTAWSNKLDDRNKKQKRREQKQRRQEKNKWEKMTEEERQKIRETEQMVESIRVKNEEERRLRRAGKAEAANAGKDEEEFEGFD
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase spb4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PAND_STUS1
Sequence: MHAIMLKAKLHRAQVTHSVLDYEGSCAIDGEWLDLAGIREYEQIQIYNVDNGERFTTYAIRGEEGSRIISVNGAAAHKAGVGHRLIICAYAHYSEAELANFKPHVLYMGADGELSHTSNAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
Protein: AHPD_MYCBP
Sequence: MSIEKLKAALPEYAKDIKLNLSSITRSSVLDQEQLWGTLLASAAATRNPQVLADIGAEATDHLSAAARHAALGAAAIMGMNNVFYRGRGFLEGRYDDLRPGLRMNIIANPGIPKANFELWSFAVSAINGCSHCLVAHEHTLRTVGVDREAIFEALKAAAIVSGVAQALATIEALSPS
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: RECX_STRPQ
Sequence: MKITKIEKKKRLYLIELDNDDSLYVTEDTIVRFMLSKDKVLDNDQLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQWIDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQKLFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQNNQEIEDLLDKELDKQYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMG_AERS4
Sequence: MQTLLDTAHCRLTLYRYPRQSQDPLQAWDAADEYLINTLAETPLEQAGPVIIMNDGFGALAAFLHPHAPVCVSDSYISERATLANLAENELDPHAIRLQDALAPLPLAPALVVIKVSKYQALLEQQLLALRAVVTPATRVIAAGKAKDIHSSTLALFEKYLGPTRTSLAWKKARLIHCEPQAMQPELANPYPTVWPLEGTGMLIHNHANVFSRTSLDIGARFMLDNLPVHSARKVIDLGCGNGVLGLALLAKDPEVEVTFIDESHMAVASARLNVEHNLPDALPRARFMVNNCLDDVAVGAADRILCNPPFHQLQAITDHIAWQMFSDAHRVLPQGGELWIVGNRHLDYHNKLKRLFANAQVVASNSKFVILKAIKR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.