PharMolix/UniProtQA huggingface dataset:
Protein: IAA_STRTE
Sequence: MRVRALRLAALVGAGAALALSPLAAGPASADTTVSEPAPSCVTLYQSWRYSQADNGCAQTVTVKVVYEDDTEGLCYAVAPGQITTVGDGYIGSHGHARYLARCL
What is the function of this protein?
Inhibits mammalian alpha-amylases specifically but has no action on plant and microbial alpha-amylases.  Forms a tight stoichiometric 1:1 complex with alpha-amylase.
What are the official names of this protein?
Alpha-amylase inhibitor HOE-467A, Tendamistat.
Protein: RS12_UREU1
Sequence: MPTIAQLIRNKRAPKVKKTKSPALLFTYNSLHKKTTKNPSPLKSGVCTRVGTMTPKKPNSALRKYAKVRLSNGFEVLAYIPGEGHNLQEHSVVVIRGGRVKDLPGVRYHIVRGAGDASGVEKRRQQRSLYGAKRPKKEASK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NU2C_ZYGCR
Sequence: MPFDPLLFAQNTVILPEIIVIVCLLIVLVLDLIQENSAWLSTISLTGLVAATIALVFQWNHPSANDFLGSIQVDNFTISFRGIITISSALSILISTEYIKRAGMGLAECLIFILTATVGGLFLCGANNLVTVFVSLECLSLSSYLLVGYAKKDVRSNEASMKYLLMGGASSSIIAYGFSWLYGLSGGEIELSKLVDGITNHIDEPIAVWVALACVVVGIGFKLSAFPFHQWTPDVYEGSPTPVVAFFSVGSKAAALALATRMLSIVFPSIESEWHVLLELLALLSMIFGNLIAATQTSMKRMLAYSSISQAGYLIIGIVCGNIYGYTGMITYMVTYIFMNLGAFGCVILFGLRTGTDQIRDYTGLYLKDPLLAFCLSVCLLSLAGIPPLAGFFGKLYLFWCGWKSGLYLLVYVALITSVISMYYYLRVVKSMFTRETKEQSSYVRNYLAPSLSLLPTTSIEVGIALCVFISTTLGFVINPIISATSETLLATNTIVG
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic, NAD(P)H dehydrogenase, subunit 2, NADH-plastoquinone oxidoreductase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: UREE_PSEFS
Sequence: MLVIHRRIAPQALWAAELLLNFEARSKSRLRCFSADGEDVGLFLERGQPPLHDGEFLQAEDGRVVRVCARPEQLLHVTCSNAFELTRAAYHLGNRHVALQVGDGWLRLLDDYVLKAMLEQLGAQTETIEAPFQPEHGAYGGGHHHSRHGDEDFNYPPKLHQFGVRL
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZPB5_ASPTN
Sequence: MSPPRFSGRQDGRTDPTTALPRVLCLHGGGTNARIFRTQCRVIRAHLADSFRLVFADGPFPSGPGPDVTAVYGDWGPFRAWLPHPAVKDPDVDKIDECIAAAMAADDRAGATGAWVGLLGFSQGARVAASLLLRQQRHQQRQKASLGFAYGATNAISEYRFAVLFAGRGPLLDMGAGDDNTRPEAELLELPTIHVHGLQDPGLEMHRDLLRCCLGSSARLVQWDGDHRVPIRRKDVSAVAAEIRDLASRGILGDG
What is the function of this protein?
Probable esterase; part of the cluster B that mediates the biosynthesis of azasperpyranones, members of the azaphilone family that exhibit anti-cancer activities (PubMed:31908094).  Azasperpyranones are synthesized by 2 clusters, A and B (PubMed:31908094).  Cluster A is responsible for the production of the polyhydric phenol moiety while the azaphilonoid scaffold is produced by the cluster B (PubMed:31908094).  The non-reducing polyketide synthase ATEG_03629 produces 5-methyl orsellinic acid, which is then reduced to 5-methyl orsellinic aldehyde by the NRPS-like protein ATEG_03630 (PubMed:24412543).  5-methyl orsellinic aldehyde is then first hydroxylated by the FAD-dependent monooxygenase ATEG_03635 and subsequently hydroxylated by the cytochrome P450 monooxygenase ATEG_03631 to produce the unstable polyhydric phenol precursor of azasperpyranones (PubMed:31908094).  On the other hand, the polyketide synthase ATEG_07659 is responsible for producing the 3,5-dimethyloctadienone moiety from acetyl-CoA, three malonyl-CoA, and two S-adenosyl methionines (SAM) (Probable).  The 3,5-dimethyloctadienone moiety is then loaded onto the SAT domain of ATEG_07661 and extended with four malonyl-CoA and one SAM, which leads to the formation of 2,4-dihydroxy-6-(5,7-dimethyl-2-oxo-trans-3-trans-5-nonadienyl)-3-methylbenzaldehyde (compound 8) after reductive release and aldol condensation (Probable).  The FAD-dependent monooxygenase ATEG_07662 is the next enzyme in the biosynthesis sequence and hydroxylates the side chain at the benzylic position of compound 8 (Probable).  In Aspergillus nidulans, afoF, the ortholog of the FAD-dependent oxygenase ATEG_07660, is the key enzyme for the biosynthesis of asperfuranone by catalyzing the hydroxylation at C-8 of to prevent the formation of a six-membered ring hemiacetal intermediate and thus facilitatings the formation of a five-membered ring to produce asperfuranone (Probable).  In Aspergillus terreus, ATEG_07660 is probably not functional, which leads to the formation of the six-membered ring hemiacetal intermediate presperpyranone instead of asperfuranone (Probable).  Finally, ATEG_03636 is involved in the condensation of the polyhydric phenol moiety produced by cluster A and the perasperpyranone precursor produced by cluster B, to yield azasperpyranone A (Probable).  Further modifications of azasperpyranone A result in the production of derivatives, including azasperpyranone B to F (PubMed:31908094).
What are the official names of this protein?
Probable esterase ATEG_07663, Azasperpyranone A biosynthesis cluster B protein ATEG_07663.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: MNME_STRR6
Sequence: MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDLNKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQLAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSDLINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGKILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLIDTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRIILLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSNARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDATPDELITQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_CALS4
Sequence: MGRYLGPSCRLCRREGIKLYLKGEKCYTDKCPLAKRGYAPGQHGQEKKKLTQYGMQLREKQKLKRYYGILERQFVRYYERAERMRGITGENLLQLLERRLDNVVYRLGFAVSRAQARQLVSHGHIEVNGKKVDIPSYLVKPGDVISVKESSRSMELIKNNLEMGRNVPDWLELNKDAFEGRVVSLPRREHIDLPVQEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: Y1010_METJA
Sequence: MINMKFFNRVEEIKEILSILEEEPNLIYFIYGPINSGKTALINEIINNRLDKNKYVVFYIDLREIFISKYDEFEAKLRATKTFGFRLIIEVLFEEYEDDKKPIEIIRSLIKDAPSLCGIPTPKNTLEEILKKKTTKNVFKYITNILMDIKREGKQPIIIIDELQKIGDMKINGFLIYELFNYFVSLTKHKHLCHVFCLSSDSLFIERVYNEAMLKERVDYILVDDFDKETALKFIDFLSEEILNKKLSDEDKELIYSYVGGKPILIINVIGKLKHKNLKDVLNILLMDEISKLKDFLSNLDYIKPKVNIEEEIIEIRKEDIINALKLFKGKYEIEVDKIPKAVYVYLVKKNILFLYPQRGTLKPQSFLVWNAIKRVL
What are the official names of this protein?
Uncharacterized ATP-binding protein MJ1010.
What is the protein family that this protein belongs to?
Belongs to the archaeal ATPase family.
Protein: RUVB_CLOK5
Sequence: MEDRIVTPLNIRGDAESEYSLRPKSLKEYIGQRKVKEKLKIFIEAAKNRKEALDHVLFYGPPGLGKTTLANIIALEMGGNLKITSGPAIERAGDLAAILTGLDDRDVLFIDEIHRLNRSVEEILYPAMEDYALDIVIGKGASTKSIRLDLPRFTLIGATTRVGLLTAPLRDRFGVLCPMDFYDQEELSEIVVRSCNILKIRIEPEASVEIGKRSRGTPRIANRLLKRVRDYSEVKGNGTIDLKTSKAALELLEVDKEGFDSIDNKILRAIIDNFNGGPVGIETLAYFIGEELDTIEDVYEPYLLQKGFIIRTPRGRIASDSAYKHFNKTRKSSNAYHKNLKQSSLFDGEV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: SERB_POLSJ
Sequence: MQPTEISPGLVVNVATPDLKLSDFKLIAFDMDSTLINIECVDEIADAAGRKAEVAAITEAAMRGEISDYKESLRQRVALLKGVSVASMDEVYRTRLRLNPGAARLVQACKDAGLKVLLVSGGFTFFTDRIRDELGIDYTRSNVLETTDGLLTGRMVDQPWGDICDGEEKRKMLLETCGQLGISPRQAIAMGDGANDLPMMGEAGLSVAYHAKPRVREQAMVAINEGGLDRLLELVK
What are the official names of this protein?
Phosphoserine phosphatase, PSP, PSPase, O-phosphoserine phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. SerB family.
Protein: Y1210_METJA
Sequence: MMFMVKIITRKVKDIEPLENALLIEGLPGIGHVGRLAAEHLVHEFKGEKFLELFCYDFPPQVLVKDDGTIEYMCAEFYAIREPKPMIVVLGNTQALSPIGQYHLAEEIVKIGIEYGANFVYTLGGFGVGKLCEEVKVYGATTSKELAKKLKEHDILFRTDGGGIVGAAGLMLMFADLNGIPGICLMGETPGYLIDPNAAKAVLEKFCKLENIEINMEELEKRAKGMEQFIEKIKKFEEEMLKAAQAKPPSEEDLRYIG
What are the official names of this protein?
Uncharacterized protein MJ1210.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HIS1_LACLA
Sequence: MIKIAITKGRIQKQVTKLLENADYDVEPILNLGRELQIKTKDDLQIIFGKPNDVITFLEHGIVDIGFVGKDTLDENDFDDYYELLYLKIGQCIFALASYPDFSNKNFQRHKRIASKYPRVTKKYFAQKQEDIEIIKLEGSVELGPVVGLADAIVDIVETGNTLSANGLEVIEKISDISTRMIVNKSSFKFKKDKIIEMVERLEDAQTN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_MANES
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ADE_WOLSU
Sequence: MPTLKELIAKLPKAELHLHIEGSLEPELMFELAQKNRIPLPYKSVEEVRKAYSFTSLQSFLDIYYAGAKVLLTESDFFDLAWAYLLRCKAQNICHTEIFFDPQTHTSRGVSFETVIEGITKALEKGEKELGISSFLIMCFLRHLSESEGFEILKSSLPFREKILGVGLDSSEVGHPPSKFERLFLECRKAGYKIVAHAGEEGDSSYIWEAIHKLQVERIDHGIRCEEDENLVEWLIQKQTPLTVCPLSNVKLQAVKNLSEHNILRLLRKGVLVTVNSDDPAYFGGYLNENYEALSEHLNASKEELKALAINSFKASFLSEEKKMDWIKQII
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: SHLD1_HUMAN
Sequence: MAARDATSGSLSEESSALDLPSACDIRDYVLQGPSQEANSEAFSSLEFHSFPYSSDVDPDTSNLNIEQNNSWTAENFWLDPAVKGQSEKEEDDGLRKSLDRFYEMFGHPQPGSANSLSASVCKCLSQKITQLRGQESQKYALRSFQMARVIFNRDGCSVLQRHSRDTHFYPLEEGSTSLDDEKPNPGLSKDITHFLLQQNVMKDL
What is the function of this protein?
Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs).  During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection.  Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres.
What are the official names of this protein?
Shieldin complex subunit 1, RINN1-REV7-interacting novel NHEJ regulator 3, Shield complex subunit 1.
What are the subcellular locations of this protein?
Chromosome.
Protein: CIROP_DANRE
Sequence: MSFLLCIGILLLPWFPCVCGKCIFDQIQRSVNVVSPPTAQYASAYRFKTQRSKRHIMPMDNLQPIRIKIWIPSESPALSDWEREKLMSAVGEAVSEVSSLLSVKRVKDRLLLNRDVNKYCKFIWRNSSTLNHMKCGRAHENYRFESCLGVIIPDEHLDGCSVYPNPEHPVPTVLRPRGPGVPDADFLLYVFTHNTEKCRAESSVLAYTAHCQTGSDGRPLAGTMVICRETLKKERYTYQHFVKVTTVIHELFHVLGFSKELLSNWKDFGVDCWSHGQVTSTDQTGQVRLYSPTVIRAMQKHFNSTHTDLGAPLENKDAALDGLSSHWEARVLQGSIMAASLVEASLVRIDAITLAALQDTGWYSVNHSRAQSLVWGEGEGSDFGSVSACHNSSAFFCTGSGLGCHFLHLNKGECVTDQYLDGCHIFKPLANASECWIEDNARSGMNEGGGEIFGSDSRCFISNITRLNNVTAYTPVSGHCYRHRCTGINKYHIQVKDSDWMDCPAGTSIEVSGYQGFIFCPENRLCKYSDLAPPTSTQRTESLFSDTTAQSDLGMMEKDAAVQPSFTSLFLVSEAKISLAAVLSLMAVFALLSAAVLLYRKNLSVRVHAASYRTPLPHILYRN
What is the function of this protein?
Plays an essential role for patterning the left-right axis.  Requires solely on the left side, downstream of the leftward flow, but upstream of dand5, a nodal inhibitor involved in left-right patterning.
What are the official names of this protein?
Ciliated left-right organizer metallopeptidase, Leishmanolysin-like peptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MI4GD_HUMAN
Sequence: MGEPSREEYKIQSFDAETQQLLKTALKDPGAVDLEKVANVIVDHSLQDCVFSKEAGRMCYAIIQAESKQAGQSVFRRGLLNRLQQEYQAREQLRARSLQGWVCYVTFICNIFDYLRVNNMPMMALVNPVYDCLFRLAQPDSLSKEEEVDCLVLQLHRVGEQLEKMNGQRMDELFVLIRDGFLLPTGLSSLAQLLLLEIIEFRAAGWKTTPAAHKYYYSEVSD
What is the function of this protein?
Functions in replication-dependent translation of histone mRNAs which differ from other eukaryotic mRNAs in that they do not end with a poly-A tail but a stem-loop.  May participate in circularizing those mRNAs specifically enhancing their translation.
What are the official names of this protein?
MIF4G domain-containing protein, SLBP-interacting protein 1, hSLIP1.
What is the protein family that this protein belongs to?
Belongs to the MIF4GD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPB_ACEWD
Sequence: MAQNIGKVVQVIGPVVDVKFQKDKLPKLNNAVNIELNGHTLVIEVAQQLGDDIVRCIAMDSTDGLMRNQEAVDTGSAIQVPVGKATLGRMFNVLGEPIDGKPFDTKDVVMHPIHRHPPSFEEQQTQPEMFETGIKVVDLICPYVRGGKIGLFGGAGVGKTVLIQELINNIATQHGGLSVFAGVGERTREGNDLYYEMMESGVINKTALCFGQMNEPPGARMRIALAGLTMAEYFRDDEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTSKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRAITEKGIYPAVDPLDSTSRILDPKIVGQEHYETAREVQEILQRYKELQDIIAILGMDELSDADKITVSRARKVERFLSQPFNVAEQFTGTAGVYVTIGDTIKGFKEILEGQHDDLPESAFLLVGTIEDAVVKAKKIKG
What is the function of this protein?
Produces ATP from ADP in the presence of a sodium ion gradient across the membrane.  The beta chain is the catalytic subunit.
What are the official names of this protein?
ATP synthase subunit beta, sodium ion specific, Na(+)-translocating ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CARA_THEVO
Sequence: MKKYLVMEDGTVLSGQGYGSYKEAYGELVFTTSMTGYLETLTDPSYVGQMLVFASPTIANYALEMGKMESNGVKVSALITKDAHIELKKGGYGREFDEFLKEQGIPGIDGIDTRMLVRKIRANGVLRSYVVNDPSHSLDFPDPMNDDLVSKAVPHHDPVFVKGEEGGTVLFIDLGSKNTLKELMLQNFSLIVVDKQTNLDEIEGYDAIFVSNGPGDPSHPSLSNVIKFLSHNIGVKPLFGICFGLQAISLAYGAKTYKMKFGHRGSNHAVTDGTHSYVTTHNHGYAVDGSTVKDFKVIGWDANDGTVEIIEGDDMFAVQFHPEASPGPHDTRWFFGEMKRRIGYA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: Y111_ACET2
Sequence: MKFVVDTHTHTIASGHAYSTVQEMAKEASANGIEMFAITDHGPAMKGAPYLYHFGNLRVIPEVLYGVRILKGVEANIIDYSGGLDMPEEYLRRLDFVLASFHDICIEPKTLEEHTEAVINVLKNPYVDAIAHPGNPQFPLDIEKVVRAAKENGKFIELNNHSFVTRKGSEENCKEFARECKKQGVRIVCGSDSHISFEVGRFDRVYKLLEEVDMPCELVMNTSVEKFDEYIKRKKERIRRK
What are the official names of this protein?
Probable phosphatase Cthe_0111.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: SUT3_STYHA
Sequence: MSSLGTEQFSERSQWVLNSPNPPPLTKKFLGPLKDNKFFTSSSSKKETRAVSFLASLFPILSWIRTYSATKFKDDLLSGLTLASLSIPQSIGYANLAKLDPQYGLYTSVIPPVIYALMGSSREIAIGPVAVVSMLLSSLVPKVIDPDAHPNDYRNLVFTVTLFAGIFQTAFGVLRLGFLVDFLSHAALVGFMAGAAIVIGLQQLKGLLGLTHFTTKTDAVAVLKSVYTSLHQQITSSENWSPLNFVIGCSFLIFLLAARFIGRRNKKFFWLPAIAPLLSVILSTLIVFLSKGDKHGVNIIKHVQGGLNPSSVHKLQLNGPHVGQAAKIGLISAIIALTEAIAVGRSFANIKGYHLDGNKEMLAMGCMNIAGSLTSCYVSTGSFSRTAVNFSAGCKTAVSNIVMAVTVLLCLELFTRLLYYTPMAILASIILSALPGLIDIGEAYHIWKVDKFDFLACLGAFFGVLFVSIEIGLLIALSISFAKILLQAIRPGVEVLGRIPTTEAYCDVAQYPMAVTTPGILVIRISSGSLCFANAGFVRERILKWVEDEEQDNIEEAAKGRVQAIIIDMTDLTNVDTSGILALEELHKKLLSRGVELAMVNPRWEVIHKLKVANFVDKIGKERVFLTVAEAVDACLSSRFANSA
What is the function of this protein?
Low-affinity H(+)/sulfate cotransporter which may be involved in the internal transport of sulfate between cellular or subcellular compartments within the plant.
What are the official names of this protein?
Low affinity sulfate transporter 3.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NQOR_BRASO
Sequence: MTKVLVLYYSAYGHIEAMANAVAEGAREAGATVDIKRVPELVPDDVAKASYYKLDQAAPIAKIEELADYDAIIVGTGTRFGRMASQMANFLDQAGGLWAKGALNGKVGGAFTSTATQHGGQETTLFTIITNLLHFGMTIVGLNYGFAGQMKLDEVTGGSPYGATTITGGDGSRQPSENELAGARYQGRVIAETAKKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: GATA4_RAT
Sequence: MYQSLAMAANHGPPPGAYEAGGPGAFMHSAGAASSPVYVPTPRVPSSVLGLSYLQGGGSGAASGATSGGSSGAGPSGAGPGTQQGSPGWSQAGAEGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYSSSGGAAGAGLAGREQYGRPGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPGRANPARHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAGPPGESLPPSSGASSNSSNATSSSSSSEEMRPIKTEPGLSSHYGHSSSMSQTFSTVSGHGSSIHPVLSALKLSPQGYPSPVTQTSQASSKQDSWNSLVLADSHGDIITA
What is the function of this protein?
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development (By similarity).  In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it down-regulates endocardial and endothelial gene expression (By similarity).  Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity).  Promotes cardiac myocyte enlargement (By similarity).  Required during testicular development (By similarity).  Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression (PubMed:15329343).  Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (PubMed:15329343).  May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, sphingosine-1-phosphate lyase (By similarity).
What are the official names of this protein?
Transcription factor GATA-4, DNA-binding protein GATA-GT2, GATA-binding factor 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: PG086_VACCT
Sequence: MASLLYLILFLLFVCISYYFTYYPTNKLQAAVMETDRENAIIRQRNDEIPTRTLDTAIFTDASTVASAQIHLYYNSNIGKIIMSLNGKKHTFNLYDDNDIRTLLPILLLSK
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex protein OPG086, EFC protein OPG086, Protein G3.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG086 family.
Protein: BORC7_HUMAN
Sequence: MMATGTPESQARFGQSVKGLLTEKVTTCGTDVIALTKQVLKGSRSSELLGQAARNMVLQEDAILHSEDSLRKMAIITTHLQYQQEAIQKNVEQSSDLQDQLNHLLK
What is the function of this protein?
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
What are the official names of this protein?
BLOC-1-related complex subunit 7, Diaskedin.
What is the protein family that this protein belongs to?
Belongs to the BORCS7 family.
What are the subcellular locations of this protein?
Lysosome membrane.