PharMolix/UniProtQA huggingface dataset:
Protein: G3PC1_HORVU
Sequence: MGKIKIGINGFGRIGRLVARVALQSDDVELVAVNDPFITTEYMTYMFKYDTVHGHWKHSDIKLKDDKTLLFGEKPVTVFGVRNPEEIPWGEAGADYVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEDKYTSDVNIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHAITATQKTVDGPSSKDWRGGRAASFNIIPSSTGAAKAVGKVLPELNGKLTGMSFRVPTVDVSVVDLTVRTEKAASYDDIKKAIKAASEGKLKGIMGYVEEDLVSTDFVGDSRSSIFDAKAGIALNDHFVKLVSWYDNEWGYSNRVVDLIRHMAKTQ
What is the function of this protein?
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.  Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_CHLAE
Sequence: MSGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQGEWTAPAPEFTATQPEVADWSEGVQVPSVPIQQFPTEDWSAQPATEDWSAAPTAQATEWVGATTEWS
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Also functions as a cell surface receptor for laminin.  Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.  May play a role in cell fate determination and tissue morphogenesis.  Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.  Acts as a PPP1R16B-dependent substrate of PPP1CA.
What are the official names of this protein?
40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Laminin receptor 1, LamR, Laminin-binding protein precursor p40, LBP/p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus. Note=67LR is found at the surface of the plasma membrane, with its C-terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus. Colocalizes with PPP1R16B in the cell membrane (By similarity).
Protein: RS16_STAA3
Sequence: MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL28_STAS1
Sequence: MGKQCFVTGRKASTGNNRSHALNSSKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RNH2_METTP
Sequence: MMLILGVDEAGKGPVIGSMFVAGVVFSEEDIFDLAACGVKDSKLLSPTRRESMERKILSIARESFVLEVTAQQIDDLRMVMSMNEIMVRAHSRVVSRLQADRAILDAADVNAERFAQRVREVSGKPIDILAEHNADRKHIVVAAASIIAKVARDRSIRDLEAALGRPLGSGYPSDPATVRFLKEWIEENGDLPSFVRKSWSTAQRLKASSV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAT2_CRYNJ
Sequence: MAHNEPITIDDAGDDFDAVEDNQAINEQYKVWKKNTPFLYDTVITHALTWPSLTCQWLPDITDVPDTDYTSQRLIIGTHTSGQANDHLIIAEVLLPKKGAGISDKALADLYDEEKQEIGSYTASPARIRAIQTINHAGEVNRARYMPQNPELIATKTVTGEVYVFDRTKHESKAPANGECKPDIRLKGQTKEGYGLSWNALKEGHILSASEDTTIGHWDIQGYSKQDPSLQPLRLYTGHSAYVADVEWHPKNENMFGSVSDDGQIMIWDTRSDNTAKASSQVQGHNAEINCISFAPSSEYLFLTGSSDNTIALWDLRKLSTKHHSFEAHTNDVLQLSWSPTSPVHFASASADRRVHIWDLDAIGAEQTPDDAEDGPPELLFVHGGHTSKVCDISWSPSSPWTIASASEDNILQVWEPSRHLRTPYEAEFDEKDLE
What is the function of this protein?
Regulatory subunit of the histone acetylase B (HAT-B) complex.  The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.
What are the official names of this protein?
Histone acetyltransferase type B subunit 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LYS4_ASHGO
Sequence: MRVVRCVRRFSASRAVSGQNTTEKIVQAHAVGLRPGHRVASGDYVSIRPAHCMSHDNSWPVALKFMGLGATRVHDARQVVCTLDHDVQNRSEKNLAKYRNIELFAAQQGVDFYPARRGIGHQIMVEEGYAFPLGLTVASDSHSNTYGGVGALGTPVVRTDAAAIWATGQTWWQVPPVARVELTGELPAGVSGKDAIVALCGVFGRDEVLNHAVEFAGPGVARLTVEQRLTVANMTTEWGALSGLFPVDGVLLDWYREQVARAPAGHARLTAARVDALAERAAAMQPDTDARYAKQLTLDLSSLTHYVSGPNSVKVARPIAELAPQQLRIDKAYLLSCTNGRLEDLEAAAAVLRADGSVRQVAPGVEFYIAAASAEVEAQARARGTWDVLLSAGCIPLPSGCGPCIGLGKGLLEAGEVGISATNRNFRGRMGSKDAEAYLASPAVVAASAVLGRIAAPCEVLGLSPPAAPAVRASVAQCGAPAAADGAAAAVEVLPGFPRAITGELVLCDADNINTDGIYPGKYTYEDDIPRETMARVCMENYDLDFQHNVHAGDIVVGGYNFGTGSSREQAATALLAKGVPLVVAGSFSNTFSRNAINNALLTLELPALLQLLRERYADAPSQATRRTGVFLTWDVAAATVTVTVGSPTGERVLHQRVGEFSANLQEIIVKGGLEGWVKHALAQSA
What is the function of this protein?
Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
What are the official names of this protein?
Homoaconitase, mitochondrial, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PGAM5_DROGR
Sequence: MRKFTAFACGTIAGLSAYYIQRLNDPQLRVHNSWTNSETPISDCALWNSNWDFRDPKSLVRPLKNDNPQEQNRYNSELEKHVPKKARHIILIRHGEYLDVGDTDDSHHLTDRGRQQAKYTGQRLHELGITWDKVIASNMVRAQETADIILNEIDYDKANVKNCPFLREGAPIPPQPPVGHWKPEGSQFFRDGARIEAAFRRYFHRAYPEQEKESYTLIVGHGNVIRYFVCRALQFPAEAWLRISINHASITWLTISASGNVSIKYLGDSGFLPAKLLTNRIPRDAKNVV
What is the function of this protein?
Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase.  Has apparently no phosphoglycerate mutase activity (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase Pgam5, mitochondrial, Phosphoglycerate mutase family member 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: PURA_CUPMC
Sequence: MSASAVGQGRNVVVIGTQWGDEGKGKIVDWLTDHAKGVVRFQGGHNAGHTLIIGGKKTILRLIPSGIMRESTVCYIGNGVVLSPEALFREIEELESAGLQVQNRLRISEAATLILPYHVAIDKAREARRGAAKIGTTGRGIGPAYEDKVARRALRVQDLFDPKHFAERLRENVEFHNFMLTQYLGAEAVDYQQILDESLAFAPRLKPMVADVSAELYAVNAAGNNLMFEGAQGTLLDVDHGTYPFVTSSNCVAGAAAAGAGVGPGRLNYILGITKAYCTRVGAGPFPSELYDNDNPARQDAVGVRLANVGKEFGSVTGRPRRTGWLDAAALKRSVQINGVSGLCMTKLDVLDGLETIKLCVGYELDGKRVDILPRGSDAVAACVPVYEEFPGWNESTFGVKTWDALPEAARVYLKRIEEVVGIPIDMVSTGPDRDETILLRHPYQVA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPH2_CRIGR
Sequence: MESTFSSPAEAALQREAGVPGLFTPPEDLDRVYELERVTKFVCDLGCQRVALQFPDQLLGDAGAVAVRLEEVTGSKMFILGDTAYGSCCVDVLGAEQAGAEALVHFGPACLSPPASLLPITFVLGQRSVALELCAKAFEARNPDPTAPVVLLSEPACAHALEALATLLRPKYQDLLISSPALPLPVGSPSSQPEPLERFGRRFPLSPGRCLEEYGAFYVGGSQASSDPVLDPDLSRLLLGWTPGRPFISCCPDTGQTQDQGVQAGRLRARRLYLIERARDAHVVGLLAGTLGVAQHREALAHLRKLTEAAGKRSYVLALGRPTPAKLANFPEMDIFVLLACPLGALAPQPSGGFFRPILTPCELEAACNPAWPPPGLAPHLTHYAELLPGSPFYVPLPPPESELWDTPDVSLISGDLRPPPSWKSSSDTGCSALTPRPQLELAESSPAASFLSSRSWQGLEPRLGQTPVKEAVQGRRGIAIAYEDEGSG
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (PubMed:21203470).  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
Protein: NAT9_NEMVE
Sequence: MKINSEVALVGNQIILVPYKEKHVPRYHEWMQSPELLEQTASERLMLQQEYDMQQSWLNDENKCTFIVLDKQKWNDNGNNEIESMAGDVNLFFNDPDDLHVAEIEIMIAEPSSRGRGLGKEALLIMMSYGISKLHVNRFTAKIGHDNEPSLSLFNKLGFTKISESEVFKEVTLKFDSNNFTNLTADVTELHYPIKTQA
What are the official names of this protein?
N-acetyltransferase 9-like protein.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
Protein: CLPB_BACC1
Sequence: MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGAEGLIKKKPSVTGSGAEAGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDINQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEATYEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTIFALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEACATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLREHLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEGEREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDMSEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVIIMTSNIGSAHLLDGLEDDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHITVELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIASTITDNSHVVVDVENNELVVHVK
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABV_BURM7
Sequence: MIIKPRVRGFICVTTHPAGCAASVREQIAYVARRGPIERGPKKVLVIGASTGYGLAARIAAAFGVGAATLGVFFERAPADAKPGTAGWYNSAAFHDEAAARGLQATSVNGDAFSDEIKHKTIDAIRRDLGQVDLVVYSVAAPRRTHPKTGVTHQSTLKPIGHAVRLRGIDTDNEAIKETLLQPATPDEIADTVAVMGGEDWRMWIDALDAAGVLADGAKTTAFTYLGEQVTHDIYWNGSIGEAKKDLDRTVLALRGKLAARGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKARSTHEGCIEQVDGLLRDSLYSAQPHVDAEGRLRADRLELDPAVQARVLELWDQVTDDNLYTLTDFAGYKAEFLRLFGFGIDGVDYDAPVEPNVRIPNLIE
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: TCPN_CLAP2
Sequence: MESVVDGSSQSRHQSENDRLNIQHALIKSIMGGKLLMAPVNLERPDLRILDSGTAQANWLLDLAALVPTTAQLTGTDIAPEQFPPPSQRPPNMTLQKQSIFDPWNEAMLGSFDVVHQRFVLAACQSDEHGQRAVADLLALTKPGGWIELHEGNMLAIQEGEAHSAMMRFRDIAVAAWVSIGQVPDPGPRLTDWMRDAGVVDMHEEVQTIGLGAAARNQQEAEWSTELCLNMLRTIRRMTAGKGADAPSEQEFDTLEVALREELQEVGNQWYYYLAYGRRRT
What is the function of this protein?
N-methyltransferase; part of the gene cluster that mediates the biosynthesis of an unusual class of epipolythiodioxopiperazines (ETPs) lacking the reactive thiol group important for toxicity (PubMed:27390873).  Firstly, L-tyrosine is prenylated by tcpD, before undergoing condensation with L-glycine in a reaction catalyzed by the NRPS tcpP leading to the diketopiperazine (DKP) backbone (PubMed:27390873).  Afterwards the alpha-carbon of tyrosine is oxidized by the cytochrome P450 tcpC to form a hydroxyl group (PubMed:27390873).  However, in contrast other ETP biosynthesis pathways studied so far, tcpC is not able to bishydroxylate the DKP at both alpha-carbon positions, but hydroxylates the alpha-carbon of the tyrosine part and the nitrogen of the glycine part (PubMed:27390873).  The next steps involve an alpha,beta-elimination reaction catalyzed by tcpI, a methylation by the methyltransferase tcpN the action of the four enzyme cascade tcpG/K/J/I (PubMed:27390873).  Due to a dysfunctional cytochrome P450 monooxygenase tcpC, the pathway leads to the biosynthesis of probable non-toxic metabolites lacking the reactive thiol group (PubMed:27390873).
What are the official names of this protein?
N-methyltransferase tcpN, Thioclapurine biosynthesis protein N.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
Protein: PSB28_PROM9
Sequence: MTANKTAKIQFYEGTDEPVVPEIRLTRSKDGTSGQALFQFEKPQALSSITDGEITGMRMIDAEGEILTREVKVKFVDGEPIFLEAVYIWKSTSDFDRFMRFANSYAKSNGLGYSEKK
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TI202_ARATH
Sequence: MASLCLSLHQTLTNPLSAPRCRPLSLSFPGSSTFSIRPSSRRATALTTRASYTPTPATERVISIASYALPFFNSLQYGRFLFAQYPRLGLLFEPIFPILNLYRSVPYASFVAFFGLYLGVVRNTSFSRYVRFNAMQAVTLDVLLAVPVLLTRILDPGQGGGFGMKAMMWGHTGVFVFSFMCFVYGVVSSLLGKTPYIPFVADAAGRQL
What is the function of this protein?
May be involved in protein precursor import into chloroplasts.  Not redundant with TIC20-I, TIC20-IV or TIC20-V.
What are the official names of this protein?
Protein TIC 20-II, chloroplastic, Translocon at the inner envelope membrane of chloroplasts 20-II, AtTIC20-II.
What is the protein family that this protein belongs to?
Belongs to the Tic20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: RLME_PARL1
Sequence: MTNSGKTGGKSGKGGTGGARALKVRVKTARKRSNSSTRWLQRQLNDPYVHAAKREGYRSRAAFKLAEIDDKYRFLKPGGRVVDLGCAPGGWCQVAVARVKAEGGDAGAEGRHGRVIGLDYLEMDPVPGATILQLDFLSEGADDQVKELLAGEADVVLSDMAAPTTGHKQTDHMRIMSLCEIAAHFATEVLAPGGTFLAKVLRGGTENELLVLLKQHFKTVRHVKPKASRADSAEMYVLAQGFKGRSESPLDDAE
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_BURP0
Sequence: MNKIRKGDEVIVITGKDKGKRGVVLAVGAEHVTVEGINLVKKHVKPNPMKGTTGGVEAKTMPLHISNVALVDANGKASRVGIKVEDGKKVRFLKTTGAVLSA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL331_STRPD
Sequence: MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTLHVET
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: LPXC_RICCN
Sequence: MQQSTLLKPVSCYGIGVHSGKRTQLTIEPTKENTGIIFIRTDISSENNYIEASYFNVSDTLLSTTISNDHKVQISTIEHLMAALWGCSIDNAIIKIDGPEVPIMDGSSKPFVFMIECAGKKLQNAPKKYLKILKDIKVVHKDCELYCTPSDHMTVDLTIDFSSKAIGRQNLSFRDQESFTKNIADARTFGFIRDVDYLKSKGLAQGASFENAIGIDEQDKILNPNGLRYEDEFVRHKLLDLFGDLYTNGTSIVSAIKGYKTSHALNNELLHRIFSDTTSYKFVTSSEL
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: CCMF_HAEIN
Sequence: MIAELGNYALALSLAVSLMLAIFPLWGAEKGNAQLMALARPMTYGLFASLSIAFAALFYLFAVNDFSVQYIVNNSNTTLPIYYRLSAVWGSHEGSLLLWIWLLAVWSFAVALLSKHLPQEAVARVLGIMGIISVGFVLFVLFTSNPFTRTFPDFPVDGKELNPMLQDVGLIFHPPLLYMGYVGFSVAFAFAIASLMTGKLDSAWARWSRPWTLAAWVFLTLGIVLGSWWAYYELGWGGWWFWDPVENSSFMPWLAGTALIHSLSVTEKRGSFKAWTVLLAILAFSLCLLGTFLVRSGILVSVHAFASDPTRGLYILAYLVVVIGGSLALYAYKGSQIRSRDNAERYSRESMLLLNNILLMTALCVVFLGTLLPLVHKQLGLGSISIGAPFFDQMFLIIMTPFALLLGIGPLVKWRRDQFSAIRTPVVICVFVMLIAGFALPYFLQDKITVSSVLGSMMTVIIALLALYELQQRATHRESFFVGVRKLSRSHWGMMLAHLGVAMTVWGIAFSQNFSVERDVRMKVGESAQIGRYDFKFTGVTDENGPNYIGGKAQIDISKDGQPEASLFAEKRFYTVSRMSMTEAAIAGGLTRDLYVALGEKLEDNSWALRLYYKPFIRWIWIGGLFMALGGLLCMFDRRYRFNVLLKK
What is the function of this protein?
Required for the biogenesis of c-type cytochromes.  Possible subunit of a heme lyase.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmF.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMP_HAEIE
Sequence: MATLEQNLQEMLQDAVEDLGCELWGIECQRMGRFMTVRLFIDKDGGVTVDDCADVSRQVSAILDVEDPIADKYNLEVSSPGLDRPLFTLPQFERYIGQDIAVHLRIPVMERRKWQGKLERIEKDMITLIVDDQEQILVFGNIQKANVVAKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17E_PYRAE
Sequence: MGRVRPRYIKSLGEKLLEMYPDKFTDNFEENKKAVAELADIPSKTVRNKVAGYITRLVKRRKAQEKAESAA
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: SYR_ECOBW
Sequence: MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIL1_ECOLI
Sequence: MNAVLSVQGASAPVKKKSFFSKFTRLNMLRLARAVIPAAVLMMFFPQLAMAAGSSGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVKFLAGFAIISVFIAVGMAVVGL
What is the function of this protein?
Propilin is the precursor of the pilus subunit, pilin, that forms conjugative pili, the filamentous surface appendages required for cell-to-cell contact during the earlier stages of bacterial conjugation, and that retract after contact is established.  Mature pilin is assembled with the help of TraQ and TraX (PubMed:1464628, PubMed:6090426).  Functions as a receptor for CdiA-CT from E. cloacae and E. coli, although it is not clear if this is physiologically relevant (PubMed:24889811).
What are the official names of this protein?
Pilin, F-pilin.
What is the protein family that this protein belongs to?
Belongs to the TraA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Secreted. Note=Propilin is directed to the inner membrane, where it is cleaved and acetylated. Mature pilin forms filaments that are secreted to form the conjugative pilus.
Protein: TTCA_PSYCK
Sequence: MTAATLFTPSITPQFDKASIDIDVNHHDKTTDIEQMLYDDVDDRNDDFMDEQADNILADTQSLTESVHFRKLQKKLRRQVSWAIRDFNMIEDGDVVMVCVSGGKDSYTLLDILLLLKRIAPIHFDIVAVNLDQKQPGYPEEVLPAYLNEQGIAHYILEKDTYSIVKSVVPEGKTYCSACSRLRRGSLYGFAKQIGATKIALGHHRDDMLATFFLNLFHGGALKSMPPKLLSDDKQNMLIRPLAYVEEKDIIEYSNLKEFPIIPCNLCGSQTNLQRAIINDMLREWDDAHPQRLASIFKAMQNVAPSQLADRELFDFETLSLDRDDNERLFEGDNIQAGQIESLAEIGLPVSPETQIFNPDFANAEKGSRAPKKIPTINPVI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRB2_HUMAN
Sequence: MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
What is the function of this protein?
Does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element.  Acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
What are the official names of this protein?
Growth factor receptor-bound protein 2, Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2.
What is the protein family that this protein belongs to?
Belongs to the GRB2/sem-5/DRK family.
Protein: NAA40_XENLA
Sequence: MGRKSVRAKEKKQKRLEERAAMAAVCAKVQAANQLGDPLGAFPVFKKFDRNGLNLSIECCKVSDLDQKTIDWAFELTKTNMQLLYEQSEWGWKEREKREELTDERAWYLIARDELAALVAFVHFRFDVECGDEVLYCYEVQLETRVRRKGVGKFLVQILQLMANSTQMKKVVLTVFKHNHGAYQFFRDALQFEIDETSPSVSGCCSDDCTYEILSKRTKFGDTPHSHTGHCAGCCH
What is the function of this protein?
N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A.  In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence'.
What are the official names of this protein?
N-alpha-acetyltransferase 40, N-acetyltransferase 11, N-alpha-acetyltransferase D, NatD.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. NAA40 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.