PharMolix/UniProtQA huggingface dataset:
Protein: MYC_FELCA
Sequence: MPLNVSFANRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAFASFSPRGDDDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPSPARGPGGCPTSSLYLQDLTAAASECIDPSVVFPYPLNDSSSPKPCASPDSAAFSPSSDSLLSSAESSPRASPEPLALHEETPPTTSSDSEEEQEEEEEIDVVSVEKRQPPAKRSESGSPSAGGHSKPPHSPLVLKRCHVPTHQHNYAAPPSTRKDYPAAKRAKLDSGRVLKQISNNRKCISPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAGEQKLISEKDLLRKRREQLKHKLEQLRNSCA
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: DPEP3_MACFA
Sequence: MQPTGHEGSRALSRRHLRRLLLLLLLLLLRQPVTRGETTTGAPRALSTLGFPSPFTTPGVPSTLTTPGLTTPGTTKTLDLRSRAQALMRDFPLVDGHNDLPQVLRQRYKNVLQDVNLRNFSHSQTSLDRLRDGLVGAQFWSASVSCQTQDQTAVRLALEQIDLIRRMCASYSELELVTSAEGLNSSQKLACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLTFTCNTPWAESSTKFTHHMYTNVSGLTSFGEKVVEELNRLGMMIDLSYASDTLMRRVLEVSRAPVIFSHSAARAVCDNSLNVPDDILQLLKKNGGIVMVTLSMGVLQCNLLANVSTVADHFDHIRAVIGSEFIGIGGNYDGAGRFPQGLEDVSTYPVLIEELLSRSWSEKELQGVLRGNLLRVFRQAEKVREESRAQSPMEAEFPYGQLSTSCHSHLVPQNGHQATHLEVTKWPTNRVPWRSSDASPYLLPGLVAAATFPTVIQWLC
What is the function of this protein?
Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem (By similarity).  The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide (By similarity).  A tyrosine (instead of histidine) at position 269 reduces affinity for the beta zinc and may cause substrate steric hindrance (By similarity).
What are the official names of this protein?
Dipeptidase 3.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor, GPI-anchor.
Protein: URE3_ACIAC
Sequence: MELTPREKDKLFLFTAALLAERRKARGLKLNYPEAVALISAAVLEGARDGKTVAQLMSEGREVLTRADVMDGVPEMISDIQVEATFPDGTKLVTVHQPIA
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYRC_HUMAN
Sequence: MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRKSLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM
What is the function of this protein?
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis (PubMed:25288775).  Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1 (PubMed:17443684).
What are the official names of this protein?
Arginine--tRNA ligase, cytoplasmic, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol.
Protein: YOJI_ECOLI
Sequence: MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETADTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQLGSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAITIWGGFVLVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDAQEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLRTPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFAYQDNAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQPEDYRKLFSAVFTDVWLFDQLLGPEGKPANPQLVEKWLAQLKMAHKLELSNGRIVNLKLSKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISHDDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA
What is the function of this protein?
Mediates resistance to the antibacterial peptide microcin J25, when expressed from a multicopy vector.  Functions as an efflux pump for microcin J25, with the help of the outer membrane channel TolC.
What are the official names of this protein?
ABC transporter ATP-binding/permease protein YojI.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CD048_SALSA
Sequence: MVSSGYLQAVMLLLAVQLLCFRPSDAEQEAGTVIPAESRPCVDCHAFEFMQRALQDLKKTAFNLDARTETLVLRAERRALCDCMPTNTLR
What are the official names of this protein?
Neuropeptide-like protein C4orf48 homolog.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_MYCSZ
Sequence: RKGRRDKIGKVKTAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLTSQVEVTAYIPGEAHNLQEHSMVLVRGGRVKDLPGVRYK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity).
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GMSS1_HALMA
Sequence: MTGKYMPRTVILGVIGSDAHVVGITILEQALSAAGFEVINLGVQTAQDEFVSAAKSHDAEAVLVSSLYGHARQDCEGLHDELDDAGLDVLTYVGGNLAVGQSDFEETQATFRQMGFDRVFDAETDPEEAIEMLREDLQLTTTEAEQIRVDG
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase sigma subunit 1, Glutamate mutase S chain 1, Glutamate mutase small subunit 1, Methylaspartate mutase 1.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmS subunit family.
Protein: MDTA_ECO45
Sequence: MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQQSPAGGRRGMRAGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLSRYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNEGHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVEAQSTTTPEEKATSREYAKKGARS
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLMN_STRPC
Sequence: MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEEMTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHSVCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVMGIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVSLHAPNNDLRSRIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQELADLTKTIRKLSYVNLIPYNPVSEHDQYSRSLKERVLAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSKTMKKDREKVTATK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_TRIEI
Sequence: MSRKKKPLMSARGKPIRYKVHVKKGDTVQIIAGKDKGKVGEVLKVLPKVSKVIVKDVNIITKHVKPQQEGESGKIVTTEAPIHSSNVMLYSTKQKVASRICYTFTDDGRKVRMLKKTGEVID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SYS_FRATW
Sequence: MLDAKYIKDNLQQVAEKLATRGYQFDIAEFEAQEQKRKHLQERTQDLQSQRNTISKEIGQKKAKGEDTSDIFAKVNQINEELKIIEKELKDLQDTINQTLLSMPNLPADDVPVGKDENDNVEIRRWGTPREFHPEAPAKDHSDIGEILKMIDFKAAAKVTGSRFMVLKNKIAKLHRALSQFMLDLHTEKHGYEELYVPYLVNNDSLYGTGQLPKFAADLFKLEGDFEYSLIPTAEVPITNLVRDEILDTETLPRYYTAHTPCFRSEAGSYGRDTKGMIRQHQFEKVELVHITTADKGEESLELLTSHAEKVLQKLNLPYRVMKLCTGDMGFSAKKTYDLEVWLPSQNTYREISSCSWCGDFQARRMKARHKNPSMKKPELVHTLNGSGLAVGRTLLAIIENYQQEDGSIMVPDALIKYMGGISVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNF80_PONPY
Sequence: MSPKRDGLGTGDGLHSQVLQEQVSTGDNLHECDSQGPSKHTLVREGKTYKCKECGSVFNKNSLLVRHQQIHTGVKPYECQECGKAFPEKVDFVRHVRIHTGEKPCKCVECGKVFNRRSHLLCHHQIHTGEKPYECSECGRTFSYHSVFIQHRMTHTGEKLFGCKECGKSFYYNSSLTRHMKIHTREKPYKCSECGKTFTYHSVFFRHSMTHTAGKPYECKECGKGFYYSYSLTRHTRSHTGEKPYECLEHRKAFGYHSAFAQQSKIHSGGKNL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 80.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUR1_YEAS7
Sequence: MGSNDLINEAYDDSEVVGEERESKSAWMKRWYQLLTSPLDLQLVINEKLEMINWDAYAKSLAKPLGNFLTILFFIIRLLQDNLIKPNYYKLNVKSGAFDLSKSNKLKEFDYLWEISSSFQNSNQFYAFQSWYFVTLRFLNNLFRFTIFILLSLNLYVSCKFMFGYFKTYNLFHLKKEFNSPNLTKHNLKDLSKEYYEDIYKQSLWSMLKHFFRGSRDDGPHVNQNEVEIFFQLRKWIPTNFMINLFVSFSPTAIVFLSFSDVSFTSAIAIVFHQYILDYIITKRFQRSVDDDLILSSAALQEYEDKHIMARINQCSNIDTLSSAMGTRSKTPRIFTTHSLCGEEIREVYNYEKREFEALPKMTESVPGSRETRIKDYGGISQVSDNQSHPIGFHYSPRMSPYYRDKVLDNNLAQSSSNENLEKGGAFLPNQDQNRPSKSLSPLRKTPLSARQKRFEGSEFNVLNKNDINSILRSPKKKKNYHKR
What is the function of this protein?
Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability.  Required for rDNA repeat stability (By similarity).
What are the official names of this protein?
Nuclear rim protein 1.
What is the protein family that this protein belongs to?
Belongs to the NUR1 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein.
Protein: FMDC_METTH
Sequence: MGFVLVPKSDFQIPLEADTIRPDLFEGLDLDEIRSLQVYEGNIKRPLGEFFEIAETPHADQLIRIDGDVSRVKYIGSGMKSGKIIINGDVGLQLGCEMKGGEIEVNGNVSSWIGMEMHGGTIKINGNAGDYVGCAYRGEWRGMKGGKIIIQGNAGNNIGGGMMAGEIYIGGDAGNFCGIRMNGGEITVRGDAGRAPGAEMVSGIIKIHGRISSLLPGFKEISTFKEDGSLMILFKGDLSEKNPEGNLYINYNKNLHILENETDEGRVITKKGIKVIYNSGSTIREGQIIKGGNKLTDDYIDECARCCISPEDYKLLGEPENVVVSSHGNEVVLRAVEDPGIQMGTIFIPRGIWANVLTPPYTESTGSPMYKGVPVYLRKASQGERILSAEELVEEYGVGK
What is the function of this protein?
Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR).  Can only oxidize formylmethanofuran.  This enzyme is oxygen-labile.
What are the official names of this protein?
Molybdenum-containing formylmethanofuran dehydrogenase 1 subunit C, Molybdenum-containing formylmethanofuran dehydrogenase I subunit C.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the molybdenum dinucleotide binding protein family.
Protein: FEI2_ARATH
Sequence: MGICLMKRCCSWFLLISFLSALTNENEAISPDGEALLSFRNGVLASDGVIGLWRPEDPDPCNWKGVTCDAKTKRVIALSLTYHKLRGPLPPELGKLDQLRLLMLHNNALYQSIPASLGNCTALEGIYLQNNYITGTIPSEIGNLSGLKNLDLSNNNLNGAIPASLGQLKRLTKFNVSNNFLVGKIPSDGLLARLSRDSFNGNRNLCGKQIDIVCNDSGNSTASGSPTGQGGNNPKRLLISASATVGGLLLVALMCFWGCFLYKKLGRVESKSLVIDVGGGASIVMFHGDLPYASKDIIKKLESLNEEHIIGCGGFGTVYKLSMDDGNVFALKRIVKLNEGFDRFFERELEILGSIKHRYLVNLRGYCNSPTSKLLLYDYLPGGSLDEALHKRGEQLDWDSRVNIIIGAAKGLAYLHHDCSPRIIHRDIKSSNILLDGNLEARVSDFGLAKLLEDEESHITTIVAGTFGYLAPEYMQSGRATEKTDVYSFGVLVLEVLSGKLPTDASFIEKGFNIVGWLNFLISENRAKEIVDLSCEGVERESLDALLSIATKCVSSSPDERPTMHRVVQLLESEVMTPCPSDFYDSSSD
What is the function of this protein?
Involved in the signaling pathway that regulates cell wall function, including cellulose biosynthesis, likely via an 1-aminocyclopropane-1-carboxylic acid (ACC)-mediated signal (a precursor of ethylene).
What are the official names of this protein?
LRR receptor-like serine/threonine-protein kinase FEI 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SP130_MOUSE
Sequence: MSSQQFPRLGTPSPGLSQPPSQIASSGSAGLINQVATVNDEAGRDADVGTREHVGPSSSLPPREEKQEPVVVRPYPQVQMLPAHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTMSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHLIHQPIQSRPPVTTSSTIPPAVVATVSATRAQSPVITTTAAHAADSTLSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTLPSTTTAGSVSHTQAPTSTIVTMTMPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPPERSSLIPISGHRASPNPVAMETRNDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSTITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTSGIQPAPIGTPGIHSAAPINTQGLQPAAMANQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSILRKKPATDGMAVRKTLLPPQPPDVATPRVESSMRSASGSPRPAGAKPKSEVHVSIATPVTVSLETISNQNAEQPTVAVPPTAQQPPPTIPSMIAAASPPSQPAIALSTIPGAVPVTPPITTIAATPTLSAPVGGTPSTVLGPPVPEIKVKEEAEPVDITRPVSTVPPLATNTVSPSLALLASNLSMPPSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSAAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRKEKV
What is the function of this protein?
Acts as a transcriptional repressor.  May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity).
What are the official names of this protein?
Histone deacetylase complex subunit SAP130, 130 kDa Sin3-associated polypeptide, Sin3-associated polypeptide p130.
What is the protein family that this protein belongs to?
Belongs to the SAP130 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARNA_ECO55
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDDVNHPLWVERIAQLSPDVIFSFYYRHLICDEILQLAPAGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: METN_STRPQ
Sequence: MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYSGAGKSTLVRVINLLQAPTNGKITVDGDVTFEQGKVQLSANALRQKRRDIGMIFQHFNLMAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAIARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICNRVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANALLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENILAAEKALHEAGVDVSILKRGA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ARGA_YERPY
Sequence: MKERSTELVQGFRHSVPYINAHRGKTFVVMLGGEAIEHENFSSIVNDIGLLHSLGIRLVVVYGARPQIDSNLADHNYEPIYHKHTRVTDARTLEMVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEEAIHRQLDNGAIVLLGPVAVSVTGESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVTDSEGNIISELFPNDAQKRIEDLEQDGDYNSGTVRFLRGAVKACRSGVRRSHLLSYQEDGALIQELFSRDGIGTQIVMESAEQVRRATINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIERDNLTIACAALYPFPDEHIGEMACVAVHPDYRSSSRGEMLLNRITNQARQMGLKKLFVLTTRSIHWFQERGFTPAEVDVLPIQKQELYNYQRRSKILLADL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFV_ENTAG
Sequence: MAASESERTGGGNRPMAVIINDTTLRDGEQSPGVAFRASEKLEIAQALVNAGVRELEAGTPALGEEECVRLAILRRQLPDTVMMSWCRMNSAEIHDSARVGMDWVDISVPASDLLREQKLHRPWPAVIASLKPLVQLAHRLGMRVCMGCEDASRSADETLHMLAEVAADLGIERMRFADTLGILDPFSTFTRISALRQHWHGGLEIHAHNDLGMATANTLAAVRAGATHVNTTVLGLGERAGNAALESVTLSLDRCLHLDCGIDFTELPALCRLVAAAAGRTIDVQHPLVGGQVFTHESGLHVAALLRDPRSYQGIDPSLVGREFNLVLGKHSGRQAVSGICARLGYILSETQTLLMLQEVKRFAEHFKRNPGEDEVIAMCQMRMDDQIPFEGQLQAQGG
What is the function of this protein?
This protein is a Fe-Mo-cofactor biosynthetic component.
What are the official names of this protein?
Homocitrate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: ACP3_HORVU
Sequence: MASIAGSAVSFAKPVKAINTNSLSFSGARRGNAFLRLQPVPMRFAVCCSAKQDTVEKVCEIVKKQLAVPEGTEVCGTTKFSDLGADSLDTVEIVMGLEEEFQISVEETSAQAIATVEDAATLIDKLVSAKSS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein 3, chloroplastic, Acyl carrier protein III, ACP III.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS1_XYLFM
Sequence: MSASTVLPVRDRLRIAIQKSGRLTEPARRLLTSCGLSWRQSRDKLFCYGESLPVDLLLVRDDDIPGLIAQGVCDLGIVGRNELDEQAASRRRNGLPVPYQTLRGLHFGQCRLMLAVPEEWEWQDISQLTGKRIATSYPAILADWLQTHHIAAQIVELSGSVEIAPRLGTADLICDLVSSGATLTAHQLKPVIQIMESQAVLAGMIRQPADARAGLLAMLLRRIDGMVNLRDSNLLMFRAFQEHLDALTRLLPDADPLVQLPDDGSGTLRVQTMCHGTITWQRLEELERAGAQGLMVLTVERSLA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA77_DANRE
Sequence: MESPRIGVVRDSMLHRPLLIKPTLGKSKSRGLSYPGPEFVFGTATTVQDGGVQEAISNWHTHTMSTTHRAAERDFIALNREGVKSGLVTAKELHQYRATHDIRRKPLTREGFRRSAPPRLSPDDSFFVSNRPSTPISELIEYKYAQRWLEEQQVRDRVLQAHQHKKAQLGRIQDTRTTLLRKSQPLPEAPSTWKLPRFQKVGAALDTFRDPEARKKAMNAHCSESVSRRGILGQGTYTVD
What are the official names of this protein?
Cilia- and flagella-associated protein 77.
What is the protein family that this protein belongs to?
Belongs to the CFAP77 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: ATPG_RICB8
Sequence: MSNLKQLRTRIKSVKSTQKITKAMQLVSASKLTKIKNQIAHSNFYVEAISKMMSTVLSADIYDFPIEAQKFFNTETNKANLLIVMTSERGLCRTFNYMIIKQVKSDIETLKSKGEKIKLIIIGKKGYEALKKPYESYIDSYFELPKNHDENLMLQIKQKIMALVANLEVSNCTIYFNRFKNAMTQSMTKQQILPIEKYHDDSKIEEANYEYEGENLIQNLINLYVNSQINYALLQNRASEEGSRMTAMENATNNAHDIINKLVLKLNRSRQAIITMELIEIIAGSEAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARF5_MOUSE
Sequence: MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor 5.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor.