PharMolix/UniProtQA huggingface dataset:
Protein: CAF20_PICGU
Sequence: MVKYTEDELLEFQEIAYNPQPQVLDAFNQMVDEVREHANAEIERQKHLKWSNGDTYIDENGNERPYHHLNRRRGSRSGAKPNLKRKGAESVTVDDDGWATLAKPKKSFGAEEAGEERTKFRDSLKDGSVKARPNNKNLGSSKAVDPRDAIADKNTISFNAFEALGDDSDDDDE
What is the function of this protein?
Acts as an inhibitor of cap-dependent translation.  Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA (By similarity).
What are the official names of this protein?
Cap-associated protein CAF20.
What is the protein family that this protein belongs to?
Belongs to the CAF20 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBPB_BORBN
Sequence: MKIGKLNSIVMVLFFDLLVACSIGLVERTNAALESSSKDLKNKILKIKKEATGKGVLFEAFTGLKTGSKVTSGGLALREAKVQAIVETGKFLKIIEEEALKLKETGNSGQFLAMFDLMLEVVESLEDVGIIGLKARVLEESKNNPINTAERLLAAKAQIENQLKVVKEKQNIENGGEKKNNKSKKKK
What is the function of this protein?
Binds to decorin which may mediate the adherence of B. burgdorferi to collagen fibers in skin and other tissues.
What are the official names of this protein?
Decorin-binding protein B.
What is the protein family that this protein belongs to?
Belongs to the decorin-binding protein family.
Protein: RL37_SULTO
Sequence: MKGTPSFGKMNKSPTHVRCRRCGRNSFNVRKGYCAACGFGRSKKIRRYNWQNKKVNGLRLV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: GELS_XENLA
Sequence: FISKMGYPKQTQVQVLPESGETPLFKQFFKNWRDKEATDGMGVAYVPNHIAKIENVPFDVTVLHESPAMAAQHGMVDDGSGKKQIWRIENCEKVPVLESHYGQFYGGDSYIILYHYKSGGKQGQIIYTWQGDDSTKDEITASAILSAQLDEELGGGPVQVRVVQGKEPAHLISLFGGKPMIIYKGGTSREGGQTKDANVRLFQVRTSSSGFSRAVEVDNTASNLNSNDAFVLTTPSASYLWVGQGSTNVEKNGAKELLKILGVSASEIPEGQETDDFWGALGGKADYRTSARLKDKLNAHPPRLFACSNKTGRFIIEEVPGEISQDDLATDDVMLLDTWDQVYVWVGNEAQEDEKKEAIASAYKYIESDPANRDKRTPVAITKQGFEPPTFIGWFLGWEADYWDVDPLERAMAGLSS
What is the function of this protein?
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping).  It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (By similarity).  Plays a role in ciliogenesis (By similarity).
What are the official names of this protein?
Gelsolin, Actin-depolymerizing factor, ADF, Brevin.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=A cytoplasmic form may also exists.
Protein: AIM41_VANPO
Sequence: MNFMLRRNGGQFQKFGFFIRCNSTESFYSKAILGLKKDLKQAMLAKDDLKKTTIRNMLSTIKNKEIDAKDTKFDEFTLFGIYSKLINQRKDSISDYLKNNREDLAGKEEQELKLIQTYLDSLPIASPQEIDTKVEKFLNDLKEKEGTVPMKDVFSKVDWNTLTKEWKASQSMIKSSIVSKYKNIF
What are the official names of this protein?
Altered inheritance of mitochondria protein 41, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM41 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NTPPA_AQUAE
Sequence: MRVILASTSPRRSQILSLLGIEFEVIPAKVEEEVIPGKPVLTARKLAKEKALSVWRENRDAVVIGADTLVFLGNEIIGKPKDEKDAVNILKKLSGKWHSVVTALCVYSPEKVFLTHDIAKVKFRELSKEEIISYVKSGEPMDKAGAYGVQGFGATIVERIHGNFYTVMGLPIVKLYKILRELNLLAGTFS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE6_HPV11
Sequence: MESKDASTSATSIDQLCKTFNLSLHTLQIQCVFCRNALTTAEIYAYAYKNLKVVWRDNFPFAACACCLELQGKINQYRHFNYAAYAPTVEEETNEDILKVLIRCYLCHKPLCEIEKLKHILGKARFIKLNNQWKGRCLHCWTTCMEDLLP
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Sequesters tumor suppressor TP53 in the host cytoplasm and modulates its activity by interacting with host EP300 that results in the reduction of TP53 acetylation and activation.  In turn, apoptosis induced by DNA damage is inhibited.  E6 protects also host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: CODY_STAAC
Sequence: MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHSEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKEKFLDELEKSK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M710_ARATH
Sequence: MNRTIIEKVRSMLCECGLPKTFRADAANTAVHIINKYPSTAINFHVPDEVWFQSVPTYSYLRRFGCVAYIHCDEGKLKPRAKKGEEKGSYLINRIVSILYTIGIGKTSSPRKASHLGIKG
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00710, ORF120.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOB_PIPCE
Sequence: MLRNRNEGMSTIPEFSQIQFEGFCRFIDWGLAEELHKFPKIEDTDQEIEFQLFVETYQLAEPLIKERDAVYESLTYSSELYVPAGLIWKPGKDMQEQTVFIGNIPLMSSLGIFIVNGIYRIVINQILQSPGIYYRSELDHNGIFIYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVSSSAMGSNLREILENVRYPEIFLSFLNERDKKKIGSRENAILEFYQQFACVGGDPVFSESLCRELQKKFFQQRCELGRIGRRNMNRRLNLDIPQNNTFLLPRDVLAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQFGLALVRLENVVRGTICGAIRHKLIPTPQNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKSSYLGPGGLTGRTASFRIRDIHTSHYGRICPIDTSEGINVGLIGSLAIHARVGPWGSIKTPFYEISERSKRLQLVYLSPSVDEYHMVAAGNSLALNRGIQEEQAVPARYRQEFLTIAWEQIHLRSIFPFQYFSMGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGVSAISEREGKVIYTNTDKIILSGNGDTITIPLVMYQRSNKNTCMHQKTQVSRGKCIKKGQILANGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQTHVTSQGPERITKEIPHLETHLLRNLDRNGIVMLGSWVETGDILVGKLTPQTAKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWIQKKGGSSYNPETIRVYISQKREMKVGDKVAGRHGNKGIISKILPRQDMPYLQDGTPVDMVFNPLGVPSRMNVGQIFECSLGLAGDFLGRHYRVAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFDQPVLIGKSYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRSRQEVLGTTIVGGTIANPGDAPESFRLLVRELRSLALELNHFLLSEKDFQIHRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: XPT_FINM2
Sequence: MRKLEERIMKDGLVLPGNILKVDRFINHMIDPVLFEDLANEFYEKFKDKKINKILTIEVSGIAIAYACGIRFNCPVVFAKKTSSKTLGDNCYRTEVFSFTKNRSYEVMVSKEYLDEKDHVLLIDDFLANGKALEGLIDICSQANATVEGIGILIEKVFQKGGENLRRQGYTIESLARIKGFTDDSVIFED
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_PSEE4
Sequence: MNTVRETIAAIATAQGRGGVGIVRLSGPLASQAGQAITGRTLTPRHAHYGPFRDADGLVLDEGIALFFPGPNSFTGEDVLELQGHGGPVVMDMLLQRCLQLGCRLARPGEFSERAFLNDKLDLAQAEAIADLIEASSTQAARNALRSLQGAFSKRVHGLTEALIALRIYVEAAIDFPEEEIDFLADGHVLRMLDDVRSELSTVQREAGQGALLRDGMTVVIAGRPNAGKSSLLNQLAGREAAIVTDIAGTTRDVLREHIHIDGMPLHVVDTAGLRDTDDHVEKIGVERALKAIGEADRVLLVVDSTAPEASDPFALWPEFLDQRPDVAKVTLIRNKADLSGEHVGMEQSDDGHVTITLSAREDDMGLDLLRDHLKACMGYEQTAESSFSARRRHLEALRQASAHLEHGRAQLTLAGAGELLAEDLRQAQQALGEITGAFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB_NEIMA
Sequence: MSLNKVILIGRLGRDPEVRYMPNGEAVCNFSVATSETWNDRNGQRVERTEWHNITMYRKLAEIAGQYLKKGGLVYLEGRIQSRKYQGKDGIERTAYDIVANEMKMLGGRNENSGGAPYEEGYGQSQEAYQRPAQQSRQPASDAPSHPQEAPAAPRRQPVPAAAPVEDIDDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: RL19_STRGG
Sequence: MASLLDGVNAATLRSDVPAFRPGDTVNVHVRVIEGNRSRIQQFKGVVIRRQGSGVSETFTVRKVSFSVGVERTFPVHSPIFEKIELVTRGDVRRAKLYFLRELRGKAAKIKEKRDN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PP4C_XENLA
Sequence: MTEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANNIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKEFIIFEAAPQETRGIPSKKPVADYFL
What is the function of this protein?
Protein phosphatase that regulates many processes such as microtubule organization at centrosomes.
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 catalytic subunit, PP4C, Pp4.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: RL28_BREBN
Sequence: MARRCFVTGKSAKAGNARSHSMRATRRTWGVNVQKVRILVNGKPKRVYVSTRALKSGLVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: THOC6_ARATH
Sequence: MYGDATNWNEDEYRESILKEREIETRTVFRTAWAPPARISNPDAFVVASSDGTLAFHSLNSLVSQSASFGYSKGQDVMVAEPERVVRAHEGPAYDVKFYGEDEDALLLSCGDDGRVRGWKWREFAESDVSLHLKENHLKPLLELINPQHKGPWGALSPMPEINAMSVDPQSGSVFTAAGDSCAYCWDVESGKIKMTFKGHSDYLHTVVSRSSASQILTGSEDGTARIWDCKTGKCVKVIGSQDKKSRLRVSSMALDGSESWLVCGQGKNLALWNLPASECVQTIPIPAHVQDVMFDEKQILTVGAEPLLRRFDLNGALLSQIHCAPCSVFSISLHPAGVVAVGGYGGIVDVISQFGSHLCTFRSSSL
What is the function of this protein?
Component of the CUL4-RBX1-DDB1-DWA1/DWA2 E3 ubiquitin-protein ligase complex that acts as negative regulator in abscisic acid (ABA) signaling.  May function as the substrate recognition module within this complex leading to ABI5 degradation.  Functionally redundant with DWA2.
What are the official names of this protein?
THO complex subunit 6, AtTHO6, Protein DWD HYPERSENSITIVE TO ABA 1, WD repeat-containing protein DWA1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat THOC6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PJA1_MOUSE
Sequence: MSHQERIASQRRTTAEVPMHRSTANQSKRSRSPFASTRRRWDDSESSGASLAVESEDYSRYPPREYRASGSRRGLAYGHIDTVVARDSEEEGAGPVDRLPVRGKAGKFKDDPEKGARSSRFTSVNHDAKEECGKVESPPAARCSARRAELSKQNGSSASQISSAEGRAAAKGNNSLERERQNLPARPSRAPVSICGGGENTPKSAEEPVVRPKVRNVATPNCMKPKVFFDTDDDDDVPHSTSRWRDAADAEEAHAEGLARRGRGEAASSSEPRYAEDQDARSEQAKADKVPRRRRTMADPDFWAYTDDYYRYYEEDSDSDKEWMAALRRKYRSREQPQSSSGESWELLPGKEELERQQAGAGSLASAGSNGSGYPEEVQDPSLQEEEQASLEEGEIPWLRYNENESSSEGDNESTHELIQPGMFMLDGNNNLEDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPPPL
What is the function of this protein?
Has E2-dependent E3 ubiquitin-protein ligase activity.  Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome.  May be involved in protein sorting.
What are the official names of this protein?
E3 ubiquitin-protein ligase Praja-1, Praja1, RING-type E3 ubiquitin transferase Praja-1.
Protein: MNME_VEREI
Sequence: MRRHDPIVAIASAAGRGAIGIVRVSGNALGALAQALCGRALQPRMATYLAFRDARGQPIDQGLALYFPGPHSYTGEDVLELQAHGGPVVLQLLLARCLEAGAGADPATGRPCLPGLRLAQPGEFTERAFLNDKIDLAQAEAIADLIDASTEAAARSASRSLSGAFSAGIHGLCDALIALRTLVEASLDFPEEETDFLHQADARGQLSRLRQALGAVLQQARQGALLRDGIEVVIAGQPNAGKSSLLNALAGAELAIVTPVAGTTRDKVQQTIQIEGVPLRIIDTAGLRASDDEVERIGIARSWEAMAAADAVLFLHDLARAQTPKYIADDAEIERALARKLPPGVAVIDVWNKLDCVAAPAELAAPTAPTESAAVPPASARPAPAPRPAVQLSARTGQGLDGLRRILLEVAGWQSVPEGICIARARHVQALQMAAAHLEQAADQLQARGAALELLAEELRLAQNALDSITGAFTSDDLLGAIFARFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_BURP0
Sequence: MAVQQNKKSPSKRGMHRSHDFLTTSPLAVEPSTGEVHLRHHISPNGYYRGKKVVKTKND
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: LRB3A_RAT
Sequence: MTFTFTALLCLGLTLGLWIPVLTGSLPKPILRVQPDSVVSMGTTVTFICEETIGAKQSYLYRNGNLQRRVPKNNQKPTNKTEFLFLNVGHQNAGQYHCSYKSQGKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSHYGHTLILTVEGPQKLSWRQDPQCNYYTENCHVLFYVGPLTSNQRWIFRCYSYETNTPQVWSAPSEPVEILVSGKLQKPTIKAEPGSVIHSGKAMIIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKLFIRPVTQGHAGDYRCYYYSSAGWSEPSDTLELVVTGIYNYHPLMLSGPPSPVVPEGGNVTLHCTSHRYYDKFILIKEDQKFSSSLDTKYISSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSEPSNLLKILITGQLHHVLFLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLLSFASAPVELIVSGPIRTSDLPPTMSIPPDGLQRYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ
What is the function of this protein?
May act as receptor for class I MHC antigens.  Becomes activated upon coligation with immune receptors, such as FCGR2B and the B-cell receptor.  Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
What are the official names of this protein?
Leukocyte immunoglobulin-like receptor subfamily B member 3A.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYQ_ECO45
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDE_ECO45
Sequence: MSDIALTVSILALVAVVGLFIGNVKFRGVGLGIGGVLFGGIIVGHFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVIIGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMAMVDQMGMSYAMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESTRTNGGALIRTINIRVENPNLHNLAIKDVPILNGDKVICSRLKREETLKVPSPETVIQLGDLLHLVGQPADLHNAQLVIGQEVDTSLSTKGTDLRVARVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASSDISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVPGFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKSGGDFIHTLVDGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPPALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG
What are the official names of this protein?
Putative transport protein YidE.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS4_PARPJ
Sequence: MARYIGPKAKLSRREGTDLFLKSARRSLADKCKLDSKPGQHGRTSGARTSDYGTQLREKQKVKRIYGVLERQFRRYFAEADRLKGNTGENLLQLLESRLDNVVYRMGFGSTRAEARQLVSHKAIVVNGVVSNIPSMQVKAGDVVAVRETKKKQARILEALSLAEQGGMPSWVAVDSKKFEGTFKQKPERSDIAGDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS10_STAAW
Sequence: MAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTEKSVYTIIRAVHKYKDSREQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: YDIB_ECO24
Sequence: MDVTAKYELIGLMAYPIRHSLSPKMQNKALEKAGLPFTYMAFEVDNDSFPGAIEGLKALKMRGTGISMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEFFDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVNDISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NUSB_BACCZ
Sequence: MKRRTARERAMQALYQMDITGELEPKVAVENTLDEGEETNEFLESLVVGFVENKEVIDEAIRQNLKKWKLERISIVDRSILRVAVYEMKYMEEIPHNVTINEAIEIAKTFGDEESRRFINGVLSNIKDTL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SL9B2_PONAB
Sequence: MGDEDKRITYEDSEPSTGMNYTPSMHQETQEETVMKLKGIDANEPTEGSILLKSSEKKLQETPTEANHVQRLRQMLACPPHGLLDRVVTNVTIIVLLWAVIWSITGSECLPGGNLFGIIILFYCAIIGGKLLGLIKLPTLPPLPSLLGMLLAGFLIRNIPVINDNVQIKHKWSSSLRSIALSIILVRAGLGLDSKALKKLKGVCVRLSMGPCIVEACTSALLAHYLLGLPWQWGFILGFVLGAVSPAVVVPSMLLLQGGGYGVEKGVPTLLMAAGSFDDILAITGFNTCLGIAFSTGSTVFNVLRGVLEVVIGVATGSVLGFFIQYFPSCDQDKLVCKRTFLVLGLSVLAVFSSVHFGFPGSGGLCTLVMAFLAGMGWTSEKAEVEKIIAVAWDIFQPLLFGLIGAEVSIASLRPETVGLCVATVGIAVLIRILTTFLMVCFAGFNLKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEDYGMDVLTVAFLSILITAPIGSLLIGLLGPRLLQKVEHQNKDEEVQGETSVQV
What is the function of this protein?
Na+/H+ antiporter that extrudes Na(+) or Li(+) in exchange for external protons across the membrane.  Contributes to the regulation of intracellular pH, Na(+) content and organellar volume.  Plays an important role for insulin secretion and clathrin-mediated endocytosis in beta-cells.  Involved in sperm motility and fertility.  It is controversial whether SLC9B2 plays a role in osteoclast differentiation or not (By similarity).
What are the official names of this protein?
Sodium/hydrogen exchanger 9B2, Na(+)/H(+) exchanger NHA2, Na(+)/H(+) exchanger-like domain-containing protein 2, NHE domain-containing protein 2, Sodium/hydrogen exchanger-like domain-containing protein 2, Solute carrier family 9 subfamily B member 2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein. Endosome membrane; Multi- pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Strong colocalization with LAMP1 and TCIRG1 in osteoclasts. In beta-cells colocalizes with RAB4A and SYP. Localizes to the basolateral membrane of polarized osteoclasts.
Protein: UREF_VIBPH
Sequence: MLTDLRLYQLISPSLPVGAFTYSQGLEWAIEKGWVKDEQSLALWLTSQMQGSLATLEIPILIQLHHLLGVQNYEKAQYWCDFIVASRETKELRIEERQRGAAFAKLLPQLGIDLSERTFPLVNQTQVAAFALAAEKWEIPLVKLCSAYMWSWLENAVMAGVKLIPLGQTAGQKLLIDLTKFVPEVIEKSMRWPCDRIGSFTPAQVIASCQHETQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNB_XENTR
Sequence: MYYCNRDNCNQTDNAKDKAHPRNLIPELCRQFYNLGWVTGTGGGISLKYGDEIYIAPSGVQKERIQPDDLFVCDIDEKDISSPPPYRNLKKSQCTPLFMNAYTMRDAGAVIHTHSKAAVMATLMFPGKEFLITHQEMIKGIKKGTSGGYYRYDDMLAVPIVENTPEEKDLKERMARAMTEYPDTCAVLVRRHGVYVWGDTWEKAKTMCECYDYLFEIAVQMKQHGLDPSAIPTEEKGIV
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).  Functions in the methionine salvage pathway.  May play a role in apoptosis.
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase, APAF1-interacting protein homolog.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_TROWT
Sequence: MSSVCQVTGASPGFGYAVSHSHRRTKRRFDPNVRRRTFYVATLGRRVTLNVSVKGLRLIDKRGIDAVVRDLIKKGVKL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.