PharMolix/UniProtQA huggingface dataset:
Protein: TM258_CAEBR
Sequence: MDISKMDRYAAPVHFSSLPLLATVLCGVGLLLLAAFTMLQVTSTKYNRNVFKELFIAATSSIFLGFGSVFLLLWVGIYV
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Transmembrane protein 258, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258, Oligosaccharyl transferase subunit TMEM258.
What is the protein family that this protein belongs to?
Belongs to the OST5 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MCM6_DICDI
Sequence: MIYTDAGVDEDKATIRPNQTHQFQKVQDEAKEWTKNKFLEFLNNFKLKKKIDKNNNNNNNEDNEDNNENENEYDENGIKKEKIDKSYYRQQVERMIKNDKSSLYIDFLHLEKFDKGLGKALLMEYFRLEPAIRQGLSIFIQKYFPSFMERVNKERIVLSICCYNVSTFVHIRELRSSRIGSLCSISGTVTRTSEVRPELVIGSFICKDCNTSSLPIAQQFKYTEPTKCLNPLCSNQRRWKINLEESTFTDWQKVRVQENNSEIPGGSVPRSLEIILRGDSVETARAGDTCTFVGTMNVIPDVSKMSIGNNAQIIKGVASSTKEGSNANGKDDFGGVGGLKDLGVREMNYRVCFFSQSVRSNVSTLSSINRKESGDNHGGHSHSVGIIDEDLEPESKESFLDSLPKKEKDSLKKMIKSKKIYQNLVNSICPSIFGHEEIKRGVLLMLFGGVHKKTPEKIRLRGDINVCIVGDPSTSKSTFLKYLVSFLPRTVYTSGKASSAAGLTATVVKDQESGDFNIEAGALMLADNGICCIDEFDKMEPGDQVAIHEAMEQQTISIAKAGIHASLNARTSILAAANPIGGRYDRNKTLKQNLNIGGPLMSRFDLFFVVLDECNPESDHRIAEHIVLTHQKREKAFNAPFSATEIKNYIKYTKFICPTIPDESVQLLVGHYDRLRQMDTSGSKTPAYRITVRQLESLVRLSESLARLHLDTKVLPKYVNEAARLLEKSIVHVETNDVILGDDDDDLVKNVENDNDNHAEEDGDDGIGKLTMNFSKYSQLSKLLVLQIKQSGKEKSGIKQIDLIDWYIKDQLESGIITDDEVTKETKITKMVINKMINKDNSLVVLVPNQYPDHRILIIHPNYSFDK
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
What are the official names of this protein?
DNA replication licensing factor mcm6.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYD_ECO55
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_LACP3
Sequence: MTTKRTFQPKKRHRERVHGFMKRMSTKNGRKVLARRRAKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: MNME_NITOC
Sequence: MVHYPSDRTRRLSDTIAAIATPPGQGSVGIVRVSGPFCRQIAEQVTGRVPPPRYATFCHFRNRYGEILDQGLILYFPGPHSFTGEDVLELQGHGGPAIMDWLLSSVLQLGVRLARPGEFSERAFLNNKIDLAQAEAIADLIESASEQAARSALRSLHGEFSAQIQTLREQLTELRCVVEANIDFSDEDIDFIERGMVAERLKEIQSTLQSIHRSARQGALLREGVRVVLAGRPNVGKSSLHNRLAGFEAAIVTDVPGTTRDLLRENITIDGLPIHLSDTAGLHNSKDTIEQEGMRRTREELIHADHVLLVADDQSGLTEAEQAILDELPDDVTYTLIFNKIDLSGAPAGRWEELQGIALRLSALTGAGMDLLCQRLKECAGFDRESEGCFSARRRHLEALQRAGAAVVVARKILGDKGAEEILAEELRQAQNALAEITGEYRSDDLLGEIFSTFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_RHOP5
Sequence: MCTLANRSFAKMNGIGNEIVVLDLRDDPVAVTAAAARAIASQVPYDQLMVLQPPRAAGTAAFIRIYNNDGSESNACGNGMRCVAKQVFSGTDASALAFESRAGLLQCWRGAAPDIYTVDMGVPKFGWQDIPLAEEFRDTRMIELQIGPIDAPLLHTPSAVSMGNPHAIFWVDDVHAHDLGRFGPLLENHPIFPERANITLAHIVDRTHIVIRTWERGVGLTKACGSAACATAVAAVRLKRAERQVQISLPGGDLTIDWREADDHVLMTGGASFEFEGTLDPALFAGAA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUT2_PANTR
Sequence: MLVVQMPFSFPVAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSPIFVVTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPFLKIFKPEAAFLPEWMGIAADLSPLLKH
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation.  Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs.  Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition.  Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway.
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 2, Alpha(1,2)FT 2, Fucosyltransferase 2, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: DLTC_STAA2
Sequence: MEFREQVLNLLAEVAENDIVKENPDVEIFEEGIIDSFQTVGLLLEIQNKLDIEVSIMDFDRDEWATPNKIVEALEELR
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTR9_PONAB
Sequence: MARKQNRNSKELGLAPLADDTSHAGPPGPGRALLECDHLRSGLPDGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSIFAIGGLVGTLMVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGIALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKRNEARAVKAFQTFLGKADVSREVEEVAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAIFSGLVIEHLGRRPLLIGGFGLMALFFGTLTVTLTLQDRAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICMTGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEKIDSAVTDGKTKGRPEQVSSSTLDNYVKNRIVYMDDLTFQET
What is the function of this protein?
High-capacity urate transporter, which may play a role in the urate reabsorption by proximal tubules.  May have a residual high-affinity, low-capacity glucose and fructose transporter activity.  Transports urate at rates 45- to 60-fold faster than glucose.  Does not transport galactose.  May mediate small uptake of adenine but not of other nucleobases.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 9, Glucose transporter type 9, GLUT-9, Urate transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Protein: MMP2_MOUSE
Sequence: MEARVAWGALAGPLRVLCVLCCLLGRAIAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGTSYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRNDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSHDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
What is the function of this protein?
Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
What are the official names of this protein?
72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted, extracellular space, extracellular matrix. Membrane. Nucleus. Note=Colocalizes with integrin alphaV/beta3 at the membrane surface in angiogenic blood vessels and melanomas. Found in mitochondria, along microfibrils, and in nuclei of cardiomyocytes (By similarity). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Mitochondrion.
Protein: YBEY_PSYIN
Sequence: MQLYVDLQIACSDPNDLPMPASFEKWIEAAILGGSESHREEAELTVRIVDQDEIMQLNHQYRNISKTTNVLAFPFQNPPGLTLPLLGDLIICKEVVESEAKLQGKSLTAHWAHMSIHSTLHLLGYDHIEQAEAVEMESLETKLLTELGFTDPYLSEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_EONSP
Sequence: MTNIRKTHPLFKIINDSLIDLPTPSSISSWWNFGSLLAVCLGIQILTGLFLAMHYTSDTATAFQSVTHICRDVNYGWLLRYMHANGASMFVICLFLHVGRGLYYGSYIYTETWNVGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIIAALVMVHLLFLHETGSNNPTGIPSDADMIPFHPYHTIKDMLGALTMFLVLLMLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALMPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFSLVLVLMPLISIVENRLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NHR25_CAEEL
Sequence: MTDVERMVLRPNHEGEMCPVCGDRVSGYHYGLLTCESCKGFFKRTVQNKKQYQCSAEANCHVDRTCRKRCPSCRFQKCLTMGMKMEAVRADRMRGGRNKFGSFYKKDRAHRMQRNAMRVSTVQVPAVLGAQSQAQTFYQPPEHQVSSSTTDQNNQINYFDQTKIKTEYIKTEYDAHLQSPTLSSSTNQQLSVSDFIMRPGYLVDPQDSLAVLLGSTIDDPLLRHTFPAAYQLNEVKQEPFDYSEQFIHHSLHDYPTYTSNTTNYATMMPMTTVSSTQSLVTSTSSTTTGRMTEASSTSPILPLCPAPTEKTVDHFYNSSIAEMCKTLPDDAQIARIFTSVKGTSKPEKHAFSIQVAEENLKDIVIWAKNDQLFSKLSLDDQMILLQTSWTTVHIVDITNAMVHGNLLSQYKMSNGDEVPVGLVALLGNQTFVSSWNDVVIRLRNMGFTNFDYCAFRFLALFDQSMDSFPAVSTARSRVLQSWREVRCTTAFLEIFEQIRRLAYDSLRYLWNLHSNCPTNWEQFFPEASLVLEMIRTTVNRSASSSVTAITQVPAIQLPTPQATYTAVPYMAS
What is the function of this protein?
Orphan nuclear receptor and probable transcription activator, required during development (PubMed:10772806, PubMed:15314147).  Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop (PubMed:21408209).  Regulates vulval precursor cell (VPC) differentiation, in concert with homeobox protein lin-39 (PubMed:15314147).  Involved in promoting embryogenesis, in concert with homeobox protein nob-1 (PubMed:15314147).  May play a role in modulation of lifespan and immunity (PubMed:29748542).
What are the official names of this protein?
Nuclear hormone receptor family member nhr-25.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASTA_SHIF8
Sequence: MMVIRPVERSDVSALMQLASKTGDGLTSLPANEATLSARIERAIKTWQGELPKSEQGYVFVLEDSETGTVPGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSQEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAQGDFPACLVANENYHHFRVVLARTDPATERLILTAAQLDALKCHAGDRVRLVRLCAEEKTA
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: SG2A2_RAT
Sequence: MKLVFLFLLVTIPICCYASGSGCSILDEVIRGTINSTVTLHDYMKLVKPYVQDHFTEKAVKQFKQCFLDQTDKTLENVGVMMEAIFNSESCQQPS
What is the function of this protein?
Part of prostatein which is the major secretory glycoprotein of ventral prostate gland.  Steroid-binding protein; can bind non-polar steroids, cholesterol and a group of small proline-rich peptides.
What are the official names of this protein?
Secretoglobin family 2A member 2, C3.1, Prostatein peptide C3, Prostatic steroid-binding protein C3.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family. Lipophilin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OAF3_ZYGRC
Sequence: MVLSQDVRGASVRRRNRPTVVCTNCKRRKSKCDRQNPCSNCVRFGNKDTCHYVQNPKNTESQHGEDTDNKVKKQQPQMIKGKRNGTSSSIVGSKASSISPTGQSLDVPLVLSGKNYVNLSPSGNFVEFKRSAVTMFSYFCKRAIQDRDLYLKALVTFRSIAVEMTTNTLRGTKNYSKNPSLPESFKPLSIFDADGDPLSSDSLFRQHQLIHKSLFDKYGKYRKDEAIKIVDVCELLNDNLPSRSLFIDHILVHFESHVIHMVPIFEMEFLKYDVNNFYDKWEQSREISVKDFDHMVCCVILLITKICILSTKFARLPSELLEHFEKLDTSKYIAIIHYYMFEMKSLRKCTLRQLQILLLLRFYHWCAPEDGDGDSLQHSHILMGTIIASCQEMGISWLCIRDPGIYWFQLFGQSKRVPFILSPEDFKIIYQMIWSYVLHWDRKMFLINGQECLIGKSHLYDVTGQELSWHHRMVALDHIIMKMNDILNDSPSRVDIVALKQEWNNALRIFELIRDTKKEHLHLNFEYETTLELFRLCLSHAELTHLEQVNDVESFHLTVQSLWDQIVKLASKCHRYFYGPQEMDPYSRFFTNKIISVVADKLCTLIPAFVLRLNRFGEMGFDQMNMMVKFLFGVCSMYYNELGFDYYRCFESMFTAKISYKILNRPRNKNPWEIILEFLLCQLEKEGIKDQLRELKIIQNLPVLVSLRESLNLIPEYHRDAVKLWNTDVVPIGHSSVNFTLNLREESLEPFLVDRYSQTFNIFTSFYDHASSQLAEEAEDTSSKIQYNVENSAEQAQEIAETNAVPVEHPLSLEPTNPVNLEESNLELIRNMFEPLDFISFF
What is the function of this protein?
Transcriptional inhibitor with a significantly increased number of target genes in response to oleate.
What are the official names of this protein?
Oleate activated transcription factor 3.
What is the protein family that this protein belongs to?
Belongs to the OAF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: RL2_CALMQ
Sequence: MGKKILVQRAGRGGSQFRSPSWRRIAPLRYVQFSEEQLKTTIRGIIKELVHVTGLNAPAMHVVLENGEEMYLPAVEGVYVGKIIEFGPDAKVEPGNVMPIGKIPEGTMVCNIEKRVGDGGKYARSSGTYGVVMIHRDSTTLVQLPSGRMIEVDSRARATIGIVAGGGRIEKPFVKAGNKYHRARTKAWKYPKVRGKAMSAYAHPHGGGSHQQGGTPVKKNAPPGQKVGFYGSKCTGRGCVRWRAQQAKTQQRQQA
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CYB_CAPCA
Sequence: MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPMGIPSNADKIPFHPYYTIKDILGVLFLILSLMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALISSILILILMPLLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEYPFIAIGQIASIMYFLIILVLMPITSTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FLHD_CROS8
Sequence: MGKMHTSELLKHIYDINLSYLLLAQRLISQDKASAMFRLGISEEMASTLGDLTLPQMVKLAETNQLVCQFRFQDHQSITRLTQESRVDDLQQIHTGILLSTRLLNEASGTEDVARKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_DESAH
Sequence: MGSYSFPKTERLLKRADFLKLSRSGRTKQTRYFIAAMLGSETDTTRLGITVSKRVGNAVERNRIKRIVRDYYRLNRDTISGNRDINIIARKYVASLNNREVRDELGKLFKKIVRSDG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PYRH_STRP8
Sequence: MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSGVQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQTAIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMAKNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMNEAGNIQRVVFGEHIGTTVSNKVCD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_ALIFM
Sequence: MKIYLVGGAVRDSLLNIDVKDKDWVVVGSTPQEMGSLGYQTVGQDFPVFLHPKTKEEYALARTERKSGQGYKGFTCYAEPDVTLEEDLLRRDLTINAIAQADNGELIDPYNGQQDIIDRTLRHVSDAFTEDPLRVLRVARFAARFHHLGFTIAHETMNLMKVLVDSGELSHLTAERVWQEWQKSLSSQHPEIFLSTLKECGALAIVLPELNALFGVPQPEKWHPEIDSGIHTLMVAQQAALLSQDLPTRFAAQVHDLGKGVTPESEWPSHKLHCHTGIKLIKRLCDRVRVPNDYRDLALLVCEHHSNIHRAAELRAQTFIKIFDKMDVWRKPERLAPILLCCQADHAGRLGLETQPYPQKQRFEAAFDAAKMVEVKEVVAAGFKGQEIRDELNKRRIEAVKDKLDIK
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.