PharMolix/UniProtQA huggingface dataset:
Protein: POL_XMRV3
Sequence: MGQTVTTPLSLTLQHWGDVQRIASNQSVDVKKRRWVTFCSAEWPTFNVGWPQDGTFNLGVISQVKSRVFCPGPHGHPDQVPYIVTWEALAYDPPPWVKPFVSPKPPPLPTAPVLPPGPSAQPPSRSALYPALTLSIKSKPPKPQVLPDSGGPLIDLLTEDPPPYGVQPSSSARENNEEEAATTSEVSPPSPMVSRLRGRRDPPAADSTTSQAFPLRMGGDGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLITHQPTWDDCQQLLGTLLTGEEKQRVLLEAGKAVRGNDGRPTQLPNEVNAAFPLERPDWDYTTTEGRNHLVLYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAEKIFNKRETPEEREERIRREIEEKEERRRAEDEQRERERDRRRHREMSKLLATVVIGQRQDRQGGERRRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLGDXGGQGQEPPPEPRITLKVGGQPVTFLVDTGAQHSVLTQNPGPLSDKSAWVQGATGGKRYRWTTDRKVHLATGKVTHSFLHVPDCPYPLLGRDLLTKLKAQIHFEGSGAQVVGPMGQPLQVLTLNIENKYRLHETSKEPDVPLGSTWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLGIKPHIQRLLDQGILVPCQSPWNTPLLPVKKPGTNDYRPVQDLREVNKRVEDIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSEQDCQRGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQRWLTEARKETVMGQPTPKTPRQLREFLGTAGFCRLWIPGFAEMAAPLYPLTKTGTLFNWGPDQQKAYQEIKQALLTAPALGLPDLTKPFELFVDEKQGYAKGVLTQKLGPWRRPVAYLSKKLDPVAAGWPPCLRMVAAIAVLTKDAGKLTMGQPLVILAPHAVEALVKQPPDRWLSNARMTHYQAMLLDTDRVQFGPVVALNPATLLPLPEKEAPHDCLEILAETHGTRPDLTDQPIPDADYTWYTDGSSFLQEGQRRAGAAVTTETEVIWARALPAGTSAQRAELIALTQALKMAEGKKLNVYTDSRYAFATAHVHGEIYRRRGLLTSEGREIKNKNEILALLKALFLPKRLSIIHCPGHQKGNSAEARGNRMADQAAREAAMKAVLETSTLLIEDSTPYTPPHFHYTETDLKRLRELGATYNQTKGYWVLQGKPVMPDQSVFELLDSLHRLTHPSPQKMKALLDREESPYYMLNRDRTIQYVTETCTACAQVNASKAKIGAGVRVRGHRPGTHWEVDFTEVKPGLYGYKYLLVFVDTFSGWVEAFPTKRETAKVVTKKLLEDIFPRFGMPQVLGSDNGPAFASQVSQSVADLLGIDWKLHCAYRPQSSGQVERMNRTIKETLTKLTLASGTRDWVLLLPLALYRARNTPGPHGLTPYEILYGAPPPLVNFHDPEMSKLTNSPSLQAHLQALQAVQQEVWKPLAAAYQDQLDQPVIPHPFRVGDAVWVRRHQTKNLEPRWKGPYTVLLTTPTALKVDGISAWIHAAHVKAATTPPAGTAWKVQRSQNPLKIRLTRGAP
What is the function of this protein?
Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.  This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA.  The first step in the integration process is 3' processing.  This step requires a complex comprising the viral genome, matrix protein and integrase.  This complex is called the pre-integration complex (PIC).  The integrase protein removes 2 nucleotides from each 3' end of the viral DNA, leaving recessed CA OH's at the 3' ends.  In the second step that requires cell division, the PIC enters cell nucleus.  In the third step, termed strand transfer, the integrase protein joins the previously processed 3' ends to the 5' ends of strands of target cellular DNA at the site of integration.  The last step is viral DNA integration into host chromosome.
What are the official names of this protein?
Gag-Pol polyprotein, Pr180gag-pol.
What are the subcellular locations of this protein?
[Gag-Pol polyprotein]: Host cell membrane; Lipid-anchor. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p10]: Virion.
Protein: FTHS_SACEN
Sequence: MTVPSDLDISRATALRPLEDIAAQLGLGPHLLEPYGHNVAKISLDAIEELSDRPQARYVVVSAITPTPLGEGKTTTTVGLGQALRHLGKVSAVAVRQPSMGPTFGIKGGAAGGGYSQVVPMEALNLHLTGDMHAVTAAHNLLSAMLDNHLHKGNRLGVDPHRITWRRVLDVNDRDLRNIVTGMGGRADGTPRQTGFDITAASEVMAVLALSTSLRDMRRRLGRIVVGYTRDGSPVTAEDLRAAGAMTAIMREAIKPNLMQTTENTPVLVHAGPFGNIAHGNSSVVADRIAGRCADYLVTEAGFGADMGAERFFNIKCRTSGMRPDAAVLVATVRALKAHSGRYKVVAGRPLPPEMLAENPDDVLAGAENLRKQIDNIRLHGVSPVVAVNAFPTDHGSEHDAIRRVAEEEGARVAVSNHYSEGGKGALELAEVVVEAAEEPNRFRLLYPDSADLRTKIETIATRVYGADGVSYQPAAARALADYEAIGFGSLPVCIAKTHLSLSSDPSLLGAPTGWTLPVREVRASIGAGFIYAICGEMRTMPGLGSHPAAERIDIDEHGQIVGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: ATPE_VIBAL
Sequence: MAAITFHLDVVSAEKKIFSGRVETFQVTGSEGELGIFHGHTPLLTAIKPGMVRIVKQHGHEEIIYVSGGMVEIQPGTATVLADTAIRGEELDAAKAEEAKRRAEEQIQNQHGDMDFAQAASELAKAIAQLRVIELTKKRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MINC_BORBR
Sequence: MNTESLALDFKSATLYAIRVVLHDADTTRLRAALDKRMADAGSFFENEPVVIDATRVDAPVDWPALLQALADHNLPPIGVVAEGANLQGARDAGLVPVELSTPVARAPQVIDTAPPNDVATPVPSVPEATAEAAAKAGPQDDEAYGEQADEAPAHNPESVPTRAARETTEANRPTATPPQSSSALVITKPLRSGQRVYARHTDLIVIGMVSQGAEVIADGNVHVYGPLRGKAMAGARGDTSARIFTTQLDAELLAVAGVYRVVEDKLDRALHNQPALVRLDGDTLRIEALKG
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: RHAA_CROS8
Sequence: MTTHIHQAWELAKQRFAAVGVDAEAALNQLDRLPVSMHCWQGDDVAGFENPQGQLTGGIQATGNYPGKARNAEELRADLDQALRLIPGPKRLNLHAIYLESDTPVARNEIKPAHFANWVAWARERQLGLDFNPSCFSHPLSADGFTLSHPNPEIRQFWIEHCQASRRVSASFGEQLGTPSVMNIWIPDGMKDTPVDRLAPRRRLLAALDEVIREKLNPAHHIDAVESKLFGIGAESYTVGSNEFYLGYAASRQTALCLDAGHFHPTEVISDKISAAILYVPRLLLHVSRPVRWDSDHVVLLDDETQAIAGEIIRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAQLRQLELDGDYTARLALLEEQKSLPWQAVWEMYCERHDTPADAAWLSAVRHYEQHVLSTR
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTF3A_BACSU
Sequence: MKITELLTKHTIKLNIESKEKENVIDEMVTVLDKAGKLNDRQAYKEAILNRESQSSTGIGEGIAIPHAKTASVINPAIAFGRSKDGVDYESLDGQPAHLVFMIAATEGANNTHLEALSRLSTLLMREEIRKQLLEAESEDAIIDIINQHDKDDDEEEEEEEAAPAPAGKGKILAVTACPTGIAHTFMAADALKEKAKELGVEIKVETNGSSGIKHKLTAQEIEDAPAIIVAADKQVEMERFKGKRVLQVPVTAGIRRPQELIEKAMNQDAPIYQGSGGGSAASNDDEEAKGKSGSGIGNTFYKHLMSGVSNMLPFVVGGGILVAISFFWGIHSADPNDPSYNTFAAALNFIGGDNALKLIVAVLAGFIAMSIADRPGFAPGMVGGFMATQANAGFLGGLIAGFLAGYVVILLKKVFTFIPQSLDGLKPVLIYPLFGIFITGVLMQFVVNTPVAAFMNFLTNWLESLGTGNLVLMGIILGGMMAIDMGGPLNKAAFTFGIAMIDAGNYAPHAAIMAGGMVPPLGIALATTIFRNKFTQRDREAGITCYFMGAAFVTEGAIPFAAADPLRVIPAAVVGAAVAGGLTEFFRVTLPAPHGGVFVAFITNHPMLYLLSIVIGAVVMAIILGIVKKPVTEK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in fructose transport.
What are the official names of this protein?
PTS system fructose-specific EIIABC component, EIIABC-Fru.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YP010_DEBHA
Sequence: MRATRVLLNSAKKSSIAANLPIEMYPLFAAMGVAVASGCFFTYRHFAHDKELRLWKNANLSNLDNVLNAEVHKNEAGNKDEKKEENKD
What are the official names of this protein?
UPF0495 protein DEHA2C16280g.
What is the protein family that this protein belongs to?
Belongs to the UPF0495 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FLGH_CAMJ8
Sequence: MKKVLFYVLPFAFFGCSATVDPQISMKPPAYVEELAPKQSNNVESAPGSLFGKGDNPLFSDKKAMNVNDLVTVVIQESTTQSTQANKATSRTNTSNLGGGALTGSSGVVANALNKVNAYSNIGFQTNSSNNYTGTGSQSRNESFNTTISTRVIKILSNGNYFIEGSRELLINGEKQIIQLSGVIRPYDIGQDNTIDSKYIADAKILYKTEGEVDRSTRKPWGSKVIEAIWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: TM266_HUMAN
Sequence: MAVAPSFNMTNPQPAIEGGISEVEIISQQVDEETKSIAPVQLVNFAYRDLPLAAVDLSTAGSQLLSNLDEDYQREGSNWLKPCCGKRAAVWQVFLLSASLNSFLVACVILVVILLTLELLIDIKLLQFSSAFQFAGVIHWISLVILSVFFSETVLRIVVLGIWDYIENKIEVFDGAVIILSLAPMVASTVANGPRSPWDAISLIIMLRIWRVKRVIDAYVLPVKLEMEMVIQQYEKAKVIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRFKVLEAGTWDEETAAESVVEELQPSQEATMKDDMNSYISQYYNGPSSDSGVPEPAVCMVTTAAIDIHQPNISSDLFSLDMPLKLGGNGTSATSESASRSSVTRAQSDSSQTLGSSMDCSTAREEPSSEPGPSPPPLPSQQQVEEATVQDLLSSLSEDPCPSQKALDPAPLARPSPAGSAQTSPELEHRVSLFNQKNQEGFTVFQIRPVIHFQPTVPMLEDKFRSLESKEQKLHRVPEA
What is the function of this protein?
Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum (PubMed:25165868, PubMed:30810529).  Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear (PubMed:25165868, PubMed:30810529).  Undergoes both rapid and slow structural rearrangements in response to changes in voltage (PubMed:30810529).  Contains a zinc-binding site that can regulate the slow conformational transition (PubMed:30810529).
What are the official names of this protein?
Transmembrane protein 266, hTMEM266, HV1-related protein 1, HsHVRP1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Perikaryon. Note=Present in the dendrites and soma of cerebellar granule neurons, but not in their axon.
Protein: SYI2_BACC1
Sequence: MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMAGYKVLRKAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWHILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPNMEYVKAKQEGYVYIVAKERVQDVLKEDYEVLSVHKGEELVNTSYTAPFPMKEVTNGYHVIAADFVTADSGTGLVHIAPAYGEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDSDVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGESWLIRTTAIKDTFLQNNDTVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIADLRKHSTKETPEDLELHKPYVDEVQVSCEKCGGAMNRTPEVIDVWFDSGSMPFAQYHYPFENKELFEDQFPADVIAEGIDQTRGWFYSLLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVNQFGADALRWALLVDSAPWNAKRFSERTVLEAKSKFVDTLVNVYSFYVLYANLDEYNPDETYDVKRTKLDEWVLSRLHSTTKKVRTALDDYQFTNAAREIATLVDEVSNWYVRRSRNRFWESGMNAEKAAAYETLHEVLVTISKLIAPFTPFVAEDIHLNLTGSSVHLEDYPVVNESLLQPKLEAEMDAVLQVVELGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKAFHVELDETKYTSYQLKLNFKTAGPKFGKNVNAVNDWLKQLSQDEVQNFVTTERAVYEAASGEEVVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRAVQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKQLLEENLLVKQFTFGHLTNEDDELSLGETKVRIKLSATK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase 2, Isoleucyl-tRNA synthetase 2, IleRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN8_ARATH
Sequence: MARKSLIFPVILLAVLLFSPPIYSAGHDYRDALRKSILFFEGQRSGKLPPDQRLKWRRDSALRDGSSAGVDLSGGYYDAGDNIKFGFPMAFTTTMLSWSIIDFGKTMGPELRNAVKAVKWGTDYLLKATAIPGVVFVQVGDAYSDHNCWERPEDMDTLRTVYKIDRAHPGSDVAGETAAALAAASIVFRKRDPAYSRLLLDRATRVFAFANRYRGAYSNSLYHAVCPFYCDFNGYQDELLWGAAWLHKASRKRAYREFIVKNEVILKAGDTINEFGWDNKHAGINVLISKEVLMGKAEYFESFKQNADGFICSILPGISHPQVQYSRGGLLVKTGGSNMQHVTSLSFLLLAYSNYLSHAKKVVPCGELTASPSLLRQIAKRQVDYILGDNPMGLSYMVGYGQKFPRRIHHRGSSVPSVSAHPSHIGCKEGSRYFLSPNPNPNLLVGAVVGGPNVTDAFPDSRPYFQQSEPTTYINAPLVGLLGYFSAHSTWR
What is the function of this protein?
Required for cellulose formation of the cell wall.
What are the official names of this protein?
Endoglucanase 8, Cellulase 1, AtCEL1, Endo-1,4-beta glucanase 8.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NRDI_ECO5E
Sequence: MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCGVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: NDHH_MANES
Sequence: MNVPATRKDLMIVNMGPHHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNGPELLGNIQVPKRAGYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELVYDLFEAATGMRMMHNFFRIGGVASDLPHGWIDKCLDFCDYFLTGVTEYQKLITRNPIFLERVEGVGIVGTEEAINWGLSGPMLRASGVQWDLRKVDHYECYDEFDWEIQWQKEGDSLARYLVRIGEMLESIKIIQQALEGIPGGPYENLETRRFDRERDSEWNDFEYRFISKKTSPTFELPKQELYVRVEAPKGELGIFLIGDQSGFPWRWKIRPPGFINLQILPELVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: ARNC_KLEP3
Sequence: MLTYPPVKKVSVVIPVYNEQDSLPELLRRTDTACATLGRQYEILLIDDGSSDDSARMLTEAAEAEGSHVVAVLLNRNYGQHSAIMAGFSHVTGDLIITLDADLQNPPEEIPRLVEKADEGYDVVGTVRQNRQDSIFRKSASKMINRLIQRTTGKAMGDYGCMLRAYRRHIIDAMLNCHERSTFIPILANTFARRAVEIPVMHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSIFGSVIALLGFAFGLLLVVLRLAFGPQWAAEGVFMLFAVLFMFIGAQFIGMGLLGEYIGRIYNDVRARPRYFIQRVVRQPETASKEEDRS
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BETA_PARPJ
Sequence: MAANEYDYIIVGAGSAGNVLASRLTEDADVTVLLLEAGGPDYRFDFRTQMPAALAFPLQGRRYNWAYETDPEPHMNNRRMECGRGKGLGGSSLINGMCYIRGNALDYDGWAAHAGLENWTYLDCLPYFRKAETRDAGANAYHGGDGPVHVTTSKPGNNPLFAAMVEAGVQAGFPRTDDLNGYQQEGFGPMDRTVTANGRRASTARGYLDRAKTRPNLTIVTHAVTDRVLFSGKRAVGVAYLHHGNAVNAQARREVLVCSGAIASPQLLQRSGVGRSTWLRELDVPLVHDLPGVGENLQDHLEMYIQYECKEPISLYPALQWWNQPAIGLEWMLKGTGIGASNQFEAGGFIRTRDDDLWPNIQYHFLPVAINYNGSNAIKMHGFQAHVGSMRSPSRGRVKLTSRDPNAHPSILFNYMADPLDWREFRDGIRITREIMRQPALDRYRGRELNPGAELTTDEQLDTFVRMRAETAFHPSCSCKMGYDDMAVVDNEGRVHGMEALRVVDASIMPRITTGNLNAPTIMLAEKIADRIHGREPLARVDTPYFVANGVASRKQESATV
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: SECB_CUPMC
Sequence: MSDQQQANQQDDQPFFNIQRVYLKDMSLEQPNSPGIFLESEAPSVEVQVNVGASQLQEGIFEVVVTGTVTTKVQDKVAFLVEAHQAGIFDIRNVPVEQLDPLLGIACPTILYPYLRGNIADVITRAGFQAIHLSEINFQALYEQRLQAAMEEAQGQGGDSGIVMPDGSQARH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_ARTS2
Sequence: MSPMARTAPVPAATDPAIIRNFCIIAHIDHGKSTLADRMLQYTGVVQSRDMKAQYLDRMDIERERGITIKSQAVRMPWEVDGTSYALNMIDTPGHVDFTYEVSRSLAACEGAVLLVDAAQGIEAQTLANLYLAMENNLTIIPVLNKIDLPAAQPEKYAEELANLIGGDPDEVLRVSGKTGMGVEVLLDKIVRDLPAPVGDPDAPARAMIFDSVYDTYRGVVTYVRVVDGMLHPRERIQMMSTRATHELLEIGVSSPEPTPSKGLGVGEVGYLITGVKDVRLSKVGDTVTNLAKPASQSLPGYADAKPMVFSGLYPLDGTDYPVLRDALEKLMLNDAALVYQPETSAALGFGFRVGFLGLLHLEITRERLEREYKLDLISTAPNVEYEVTLEDKRVVHVTNPSEYPTGKIAEVREPMVSATILAPNEFVGAIMELCQSRRGVMGGMDYLSEDRVEIRYRLPLAEIVFDFFDILKSKTRGYGSLDWKADGDQVADLVKVDIMLQGEQVDAFSAITHRDKAYAYGVMMTGKLRELIPRQQFEVPIQAAIGSRIIARESIRAIRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKMVGRVEVPQEAFIAALTTDESKDKAKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPOA_CHLCV
Sequence: MSDNSQNLLYDKFELPESVKMMAVEGSGGSVDKQASFVAEPLERGMGHTLGNALRRALLIGLEAPAIISFSMTGVLHEYMAIEGIVEDVTNIVLNLKGALLKKYPFQDSEDGRCTQLLKSTISVDASDLAACGGQKSITLADLLQEGGFESVNPDHVIFTVTQPMQLEIALRVAFGRGYSTSERIVLEDKGVNEIVLDAAFSPVVLVNYFVEDTRVGQDTDFDRLILHVETDGRVSPKEALAFSTQILTKHFSIFEKMDEKKIVFEEAISIEKENKDDILHKLVLGINEIELSVRSTNCLSNANIETIGELVIMPEPRLLQFRNFGKKSLCEIKNKLKEMKLELGMDLSQFGVGLDNVKEKMKSYAEKIRSKNVKG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: CRYAA_OCHPR
Sequence: MDVTIQHPWFKRALGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQEDFVEIHGKHSERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVQSGLDAGHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: MGTA_CORGL
Sequence: MEIIRPMRVAIVAESFLPNVNGVTNSVLRVLEHLKANGHDALVIAPGARDFEEEIGHYLGFEIVRVPTVRVPLIDSLPIGVPLPSVTSVLREYNPDIIHLASPFVLGGAAAFAARQLRIPAIAIYQTDVAGFSQRYHLAPLATASWEWIKTVHNMCQRTLAPSSMSIDELRDHGINDIFHWARGVDSKRFHPGKRSVALRKSWDPSGAKKIVGFVGRLASEKGVECLAGLSGRSDIQLVIVGDGPEAKYLQEMMPDAIFTGALGGEELATTYASLDLFVHPGEFETFCQAIQEAQASGVPTIGPRAGGPIDLINEGVNGLLLDVVDFKETLPAAAEWILDDSRHSEMCAAAWEGVKDKTWEALCTQLLQHYADVIALSQRIPLTFFGPSAEVAKLPLWVARALGVRTRISIEA
What is the function of this protein?
Catalyzes the addition of a mannose residue from GDP-D-mannose to GlcAGroAc2 to generate 1,2-di-O-C16/C18:1-(alpha-D-mannopyranosyl)-(1-4)-(alpha-D-glucopyranosyluronic acid)-(1-3)-glycerol(ManGlcAGroAc2).
What are the official names of this protein?
GDP-mannose-dependent alpha-mannosyltransferase, Guanosine diphosphomannose-dependent alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
Protein: MDM34_PICGU
Sequence: MSFKVNWNTLETDSLREWTSQLLTDALNSGKRPPILASDIQIKDLNFGKVAPDFEILDIGELDSDRFRGIFKINYSGDFHLTLHTRVQANPLTIYQENSNASDAAFVTPNFLLASDPFALPLDLKLSDIRISGIGIIVFSRLKGLTLVFRNDPLDSIKVTSTFDTVQVLAKFLQNQIETQIRDLFRETLPTLIHRLSLKYLSSDDSSFLDDLRPQLAALHEETVSLMDIDPDVPYSPENLSRVSALFKSRETLRLAVPKIRHSVQRCRLEKFTKTQPSLVRCLHDNLNLDLVAAPQHTNEIPVELVSGADFSKTNHVLREISSIQASNYYRSSSSRPKRRVIKLGSKKSSVKSTPSAETLASPIPSEMSSATASEHVSPTKYYQNDSHISLYHPKPRQADGAAALQLANPQSYLYHNVSSTPQLPSNSSLLAGIGLGNNYFNFASQSQISTSPIRRSSQELEDKKVTGKKSINHLDIAQLNSKLNATLHTIPDVKSHPGTGRKLDTGFEMPPPPPYQV
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: ATPA_STRPM
Sequence: MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.