PharMolix/UniProtQA huggingface dataset:
Protein: PAO1_ARATH
Sequence: MSTASVIIIGAGISGISAAKVLVENGVEDVLILEATDRIGGRIHKQNFGDVPVELGAGWIAGVGGKESNPVWELASRFNLRTCFSDYTNARFNIYDRSGKIFPTGIASDSYKKAVDSAILKLKSLEAQCSGQVAEEAPSSPKTPIELAIDFILHDFEMAEVEPISTYVDFGEREFLVADERGYECLLYKMAEEFLVTSHGNILDYRLKLNQVVREVQQSRNGVVVKTEDGSVYEANYVIVSASIGVLQSDLLSFQPLLPRWKTEAIQKCDVMVYTKIFLKFPQCFWPCGPGQEFFIYAHEQRGYFTFWQHMENAYPGSNILVVTLTNEQSKRVEAQSDQETMKEAMSVLRDMFGATIPYATDILVPRWWNNRFQRGSYSNYPMISDNQLLQNIKAPVGRIFFTGEHTSEKFSGYVHGGYLAGIDTSKSLLEEMKQSLLLQPLLAFTESLTLTHQKPNNSQIYTNVKFISGTS
What is the function of this protein?
Flavoenzyme involved in polyamine back-conversion (PubMed:16778015, PubMed:20532512, PubMed:21081665, PubMed:26973665).  Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and its acetyl derivatives (PubMed:16778015, PubMed:20532512, PubMed:21081665).  Substrate preference is thermospermine > norspermine > spermine > N(1)-acetylspermine (PubMed:16778015, PubMed:21081665).  No activity detected when putrescine, spermidine or N(1)-acetylspermidine are used as substrates (PubMed:16778015).  Plays an important role in the regulation of polyamine intracellular concentration (Probable) (PubMed:26973665).  Involved in the production of hydrogen peroxide in response to salt and cold stresses (PubMed:26973665).
What are the official names of this protein?
Polyamine oxidase 1, AtPAO1, N(1)-acetylpolyamine oxidase, Spermine oxidase.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARTP_ECO57
Sequence: MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASCFTEPQTEAFKNYLSH
What is the function of this protein?
Part of the ABC transporter complex ArtPIQMJ involved in arginine transport.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Arginine transport ATP-binding protein ArtP.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SECY_HETA2
Sequence: MTLEKNKDSFTNIIDLSLINKEQKVTFTPTKEIYTELLKKRLLTIALLVFIIKIGMAIPLPYIDQTKLLNNATSMFDLSGPGLAAVSARASQKIGLFTLGITPSINASIILQLAFVINPNLKKLQREEGESGRRKLIKYTRYLTLLLAITQSVFLIFSLRAFIFEWSILKLFELSCVLSSGAMIILWISECITKTGITNGSSFLIFLNIVSVLPEQIGMSFKNLDIFSFEGLIVILTFSITVWAAIFLQQTLYIIPLKNPKLGQNELTKKLVEDSLYLPFRLNQAGVMPVVFASYLIPILKTGGIYILLKINSFNLFPFLIKFPEVVNQSLESIVEAGLICLFALFYSGLIIDPKDVADELQKSGFFIFAIRPGEKTRNYLEKIFKELSLIGALILAFNVVLLNLVGFVFNLSIFKGFSIGSQIILLGVVTEILQKVQALVLNDVYKRIRDRNK
What is the function of this protein?
The central subunit of the protein translocation channel SecYE.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PUR5_ACIBC
Sequence: MSNSTSTPNTGLSYKDAGVDIEAGDALVDRIKSVAKRTTRPEVMGGLGGFGALCKIPKGYEEPVLVSGTDGVGTKLRLALNLNRHDTIGQDLVAMCVNDLLVCGAEPLFFLDYYATGHLNVDVAANVVTGIGKGCELAGCALVGGETAEMPGMYEGEDYDLAGFAVGVVEQSKIIDGSKVKSGDVLIGVASSGAHSNGYSLLRKILDVKNVDLTQVIDGRPLADVAMEPTRIYVKPVLELCKQVDVHAMAHITGGGLPGNLPRVLPNGAQAVINEASWEWPELFKLLQREGNVERFEMYRTFNCGVGMVIAVDANDAEKAIEVLNAQGEKAWKIGHIQENAESVEGADEKIRVIFE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_MARMM
Sequence: MPPSNSTFDTCFHIHMVSDSTGETLMEVMRASVAQFEGTTPLEHLYALVRSSKQLDRVLDEVEAYPGVIMYTIVNADLRRELETRCVELGVPAIAILDPMLATLSAYLGRPVASRAGAQRSLDADYYRRIDALNYAMAHDDGQGDDFEGADIVLLGVSRTSKTPTSVYLAHRGFRAANIPLVKDVPIPEAVFSLRNPLVVGLTASPERIVQIRRNRLLSLNEDRDTNYIDDFAVREEILFAKRLYAKHKWPTIDVTRRSIEETAAKIINLLMEKRNMTV
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: YQAE_ECOLI
Sequence: MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIHAFWVQTRD
What are the official names of this protein?
UPF0057 membrane protein YqaE.
What is the protein family that this protein belongs to?
Belongs to the UPF0057 (PMP3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ORN_AROAE
Sequence: MAQDQNHLIWLDMEMTGLQPDSDRIIEIAIVITDSQLNTVAEAPVIAVHQPDSVLDAMDEWNRNTHGKSGLTDRVKASLIGEADAEAQMLAFLQQHVPAHTSPMCGNSICQDRRFMARYMPHLEAWFHYRNLDVSTLKELAKRWRPEVYKGVEKKGKHEALADIRESIAELRHYRDNFLRLVP
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAST_MACMU
Sequence: QGPWMEEEEAAYGWMDF
What is the function of this protein?
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes.  It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
What are the official names of this protein?
Gastrin.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: P2C17_ORYSJ
Sequence: MNSFLFSALFFFWLLFCSCKASSAMGNSLPVESKFTFEEENDRIKYVVSSMQGWGEKMEDAHAAILNLDDTTSTSFFGVYDGHGGAEVALYCAKQFHIELCNHEDYHNDLINALDNVFLSMDENLQQSDAWRELVIPHDNGCMYFLKAGVCAKPFPQATYTGPAYEGSTACVVVIRGNQMIVGHVGDSRCVLSRQGGLAIDLSFDHKPCTRTESERERVQNAGGRSLGLRCEQVMGNYVVKEQWVLGDFGGGDFAFKKNKDLDREKQMLVCDPDILADDITDDMEFLVIASQGLWSCVDSADVVSYIHDRLSVEGAELRVICEEVVEFGLASGENTTVILVQFKPGAFQYQLVDPAGFGTAVSNIASTSAAPAGASDTSDEGVDDAATARPTVMGYDADSSTGSADATVDSDEVDPNATADSYNPRGHAEIVASHTDDEVYTSGSARVESGELAVPTPSANNTVADEVKVDAAVVAGGSTTAMAADEATVVSLLSTIVDNYYSINTSEEPARRLIPLPLSQPTTRFINININAENARMTYIVKRREYFLVKSSCRCGGRHQQREVTSGGAGVEHGSIGDVPPSIRRAGRWMEKGRRRGRRAGSKYAKKEEEEGASCHAGCRHFVPEIGPWSEATIPENPRLPNSDENDMDAGGEEAKQERHLVLAHELFLLSRPDLDDLANVALRSDALDAVKSDGMAPLFESLATAGVLLKPDDAAARRDARADRRGGPQARRE
What are the official names of this protein?
Probable protein phosphatase 2C 17, OsPP2C17.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: ATPE_STRPB
Sequence: MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAPLQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLRAEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MURD_STAAT
Sequence: MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVVSGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTNGKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKPHIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLYFSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIIDSLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFDELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSPACASWDQYSTFEERGEKFIERFRAHLPSY
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NENF_MOUSE
Sequence: MARPAPWWRLRLLAALVLALALVPVPSAWAGQTPRPAERGPPVRLFTEEELARYGGEEEDQPIYLAVKGVVFDVTSGKEFYGRGAPYNALAGKDSSRGVAKMSLDPADLTHDTTGLTAKELEALDDVFSKVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF
What is the function of this protein?
Acts as a neurotrophic factor in postnatal mature neurons, enhancing neuronal survival (PubMed:15605373, PubMed:31536960).  Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocytes (PubMed:16547973).  Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways (PubMed:15605373, PubMed:16547973).  Neurotrophic activity is enhanced by binding to heme (PubMed:18056703).  Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (PubMed:23576617).
What are the official names of this protein?
Neudesin, Neuron-derived neurotrophic factor, Secreted protein of unknown function, SPUF protein.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
Protein: DEAD_ECOLI
Sequence: MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRPDISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALNGDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIGRTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQQQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKREFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAIANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPHTGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRRFGGDA
What is the function of this protein?
DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.  Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity at low temperature.  Involved in 50S ribosomal subunit assembly, acting after SrmB, and could also play a role in the biogenesis of the 30S ribosomal subunit.  In addition, is involved in mRNA decay, via formation of a cold-shock degradosome with RNase E.  Also stimulates translation of some mRNAs, probably at the level of initiation.
What are the official names of this protein?
ATP-dependent RNA helicase DeaD, Cold-shock DEAD box protein A, Translation factor W2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_YERPA
Sequence: MIRILLSNDDGISAPGIQTLASALRGFAQVQIVAPDRNRSGASNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYPALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNINVPDLPLAEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYMAQEVVESWLANTEVDGEW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_RALPJ
Sequence: MTRRQRRLGILLAALVCAGAATALTLNAFRSNLVFFFSPTQIAAKEAPVAQVFRLGGLVERGSIQRERDGMTIRFIVTDTARGVPVVYHGLLPDLFREGKGVVARGRLGEDGVFVANEVLAKHDENYMPPEAADALRRAVQVNEQMAKESARSASR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: KAD_NITSB
Sequence: MKKLFLIIGAPGSGKTTDAEIIAKKHSDLIAHYSTGDLLREEVKKGTPLGATIASFIDNGQLVPLEIVMDTIKNAILNSDKEVIIIDGFPRSVEQMEALDKMLQENPSIKLEAVIEVVVSEETARERVLGRARGADDNVEVFNNRMKLYLEPLNQIEEFYEKKGLLKKIDGERTIEEIVADMESFILQKIDENA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOG2_ARATH
Sequence: MEETKSRFRRICVFCGSSSGNKTTYHDAALQLAHQLVERNIDLVYGGGSVGLMGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGIHTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQLLEEYVPKHDDFVSKMVWDNTTDAFTLEGDSF
What is the function of this protein?
Cytokinin-activating enzyme working in the direct activation pathway.  Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.
What are the official names of this protein?
Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG2, Protein LONELY GUY 2.
What is the protein family that this protein belongs to?
Belongs to the LOG family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PB2_I85A3
Sequence: MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITREKKEELQDCKIAPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGVRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKKEEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKSTKRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNILLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWEAVKIQWSQDPTMLYNKMEFEPFQSLVPKAARGQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SYFA_CHLL3
Sequence: MENSIRSLREEIAGFRISSADELEAFRLRYTVRKGLIAGLFSQLKSVDPARRPEIGNMLNQLKAEAEARVEEAALSLEKTTSPAAPTIDLSLPGRRHFTGSEHPVQKVLGEMKQIFSDMGFTVATGPELELGSYNFDMLNFPPDHPARDMQDTFFVKRDGTEDDILLRTHTSPVQVRVMLDRKPPIRVICPGKVYRNEAISARSYCVFHQLEGLYIDKGVTFADLKATIYSFARQMFGSDVQLRFRPSFFPFTEPSAEVDVTCYLCGGKGCRVCKKSGWLEIMGCGMVHPNVMKNAGIDPEVWSGYAFGMGVDRTVLLKYKIDDIRLLFENDLRMLRQFPA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLY_ZINVI
Sequence: MATTILPLILFISSLAIASSSPSRTPHAIVNEVHKSINASRRNLGYLSCGTGNPIDDCWRCDPNWANNRQRLADCAIGFGKNAMGGRNGRIYVVTDPGNDDPVNPVPGTLRYAVIQDEPLWIIFKRDMVIQLRQELVMNSHKTIDGRGVNVHIGNGPCITIHYASNIIIHGIHIHDCKQAGNGNIRNSPHHSGWWTQSDGDGISIFASKDIWIDHNSLSNCHDGLIDAIHGSTAITISNNYMTHHDKVMLLGHSDSYTQDKNMQVTIAFNHFGEGLVQRMPRCRHGYFHVVNNDYTHWEMYAIGGSASPTIYSQGNRFLAPNTRFDKEVTKHENAPESEWKNWNWRSEGDLMLNGAYFRESGGRAASSFARASSLSGRPSTLVASMTRSAGALVCRKGSRC
What is the function of this protein?
Involved in the degradation of pectin.  May assist in the removal and modification of an existing pectin matrix in order to allow the deposition of newly synthesized walls polymers for a specialized function or to create an architecture that is extensible.
What are the official names of this protein?
Pectate lyase, ZePel.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
Protein: NORM_BACHK
Sequence: MKETNSFSQKLKQFALLFFPIFVTQMSLFAMSFFDTTMSGHASPIDLAGVAIGTSIWIPVSTGLTGILMATTPIVAQLVGSKKKEDVPHVVIQAVYLAICASFVVILIGLFTVTPILNGMRLEEPVERIAAQFLSIIAIGIIPLFTYTVLRGFIDALGKTRTTMIITLLSLPINVVLNYVLIFGNFGFPKLGGVGAAIASAATYWCILIITVMIIRTKEPFASFNIFKQLYRPSLSSWKEFLKLGVPIGFAIFFETSIFAAVTLMMSNFSTTTIAAHQAAMNFASLLYMTPLSLAMAMTIAVGFEVGAKRYNNAKQYGFIGIGLALAFALLYSILLYFFDDEIASIYTTDIQVHHLAKEFLIFAILFQISDAIATPVQGALRGYKDVNVALIMTLIAYWVIGLPLGYILATYTDWAAKGYWIGLIIGLAFGATFLLIRLFQVQRKYTTQNSRS
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AQDR_RHOER
Sequence: MTDPEHSGQRAQVRGARFRERVLDATIACITEAGVDNVGFADVARKAGVNGVSLYRRWKTVPRLLIDALLTRTQAEVPIPDTGSVHRDLEIFATELTKFAQTPIGTALIRFTVVSADSPEVDVSRREFWMQRLTAAEEIIERGKNRGEVDSSTDSRLVVLTLGGLVHIYVTHLGTDIPTSLPHQAVSLILSGVTSGVTQARTNAQMG
What is the function of this protein?
May regulate the expression of genes involved in the degradation of the Pseudomonas aeruginosa quorum sensing signal molecules HHQ (2-heptyl-4-quinolone) and PQS (2-heptyl-3-hydroxy-4-quinolone).
What are the official names of this protein?
HTH-type transcriptional regulator AqdR.
Protein: SYK_SHESW
Sequence: MTEQVQDENKLIAERRAKLDSIRPNCSANAHPNTFRRTHKAAELQEKYGQNTKEELEALGFRTSIAGRIMAKRGPFLVIQDVSGRIQAYAEKGVQADLKDRYQGLDIGDIIGVTGQLHLSGKGDLYVNMEEYQLLTKALRPLPEKFHGLTDQETRYRQRYVDLIVNEESRQAFVMRSKVVAAIRNFMIKKEFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEELLSSIAIELLGSAQMPYGEHTVDFGGPYARLSMLEAIQKYNPDNATIQAMTYEQVKDLEFMRELAISLGIKIEKFWTCGQLLEEIFGETAEWQLMQPTFITGYPADISPLARRNDDNHFITDRFEFFIGGREVANGFSELNDAEDQDSRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVMLFTNTHTIRDVILFPAMRPQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_FRATO
Sequence: MKEISGIKVKVESGSKYTTDHGFYAVKDGIRNKKENAVHVRKPDWLKVQKQDSKEYLKVKSITKKHKLSTVCEEARCPNINECWSHGTATIMLMGSVCTRACKFCSVDTGNPKGWLDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDENIKVEALTPDFAGINENIDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLNFLKYVKQKSPNVLTKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRKVGLEKGFLEVASGPMVRSSYRADRVFKRNNLDL
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_GEOKA
Sequence: MSLLLEPSAAMIKEQKLYREMGLTDEEFARIEAILGRLPNYTETGIFAVMWSEHCSYKNSKPVLKKFPTDGPHVLQGPGEGAGIVDIGDGLAVAFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIALLNSLRFGELTSPRVKYLFEQVVAGIAGYGNCVGIPTVGGEVQFDPAYEGNPLVNAMCVGIIRHEDIQRGVATGVGNTVMYVGAKTGRDGIHGATFASEELSEQSEAKRPAVQVGDPFMEKLLLEACLEAVKSDALVGIQDMGAAGLTSSSAEMASKGGFGIEMNLDLVPQREAGMTPYEMMLSESQERMLLVVKQGCEDEIAAIFAKYGLEAKAIGKVTDDKMLRLLFRGEVAAEIPVDALAKDAPVYHKPSAEPAYYREFQAMPPYTPHIEDYNQTLLGLLAQPTIASKEWVYDQYDYMVRTNTVVAPGSDAAVVRIRGMNKALALTTDCNSRYLYLDPETGGKIAVAEAARNVICSGAKPLAITDCLNFGSPEKPEIFWQLEKAVDGMSEACRALGTPVVSGNVSLYNETNGEAVYPTPVVGMVGLIDDLSHITTQSFKQAGDLIYVIGEAKPEFGGSELQKWLEGRIFGKAPEIDLEVEASRQRQLLAAIRAGVVASAHDIAEGGLAVALAECVMGASGLGAKVTIGGDLVSELFSETQSRFVISVKKEHQEAFEQLVEAKRIGEVTGDGILTVNGEQGETVIRLSVDEMRNVWKGAIPCLLKSKD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_VIBC3
Sequence: MSNRKPYVREMKRTWWKDHPFYRFYMVREATVLPLILFTLFLTVGLGSLVKGPEAWQTWLDFMANPLVIAINLVALAGSLFHAQTFFSMMPQVVPIRLGGKLVDKKIIVLAQWAAVAFISLIVLIVV
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.