PharMolix/UniProtQA huggingface dataset:
Protein: RS1_RHIME
Sequence: MSATNPTRDDFAALLEESFAKTDLAEGYVAKGIVTAIEKDVAIVDVGLKVEGRVPLKEFGAKAKDGTLKVGDEVEVYVERIENALGEAVLSREKARREESWQRLEVKFEAGERVEGIIFNQVKGGFTVDLDGAVAFLPRSQVDIRPIRDVTPLMHNPQPFEILKMDKRRGNIVVSRRTVLEESRAEQRSEIVQNLEEGQVVEGVVKNITDYGAFVDLGGIDGLLHVTDMAWRRVNHPSEILNIGQQVKVQIIRINQETHRISLGMKQLESDPWDGIGAKYPVGKKISGTVTNITDYGAFVELEPGIEGLIHISEMSWTKKNVHPGKILSTSQEVDVVVLEVDPTKRRISLGLKQTLENPWQAFAHSHPAGTEVEGEVKNKTEFGLFIGLDGDVDGMVHLSDLDWNRPGEQVIEEFNKGDVVRAVVLDVDVDKERISLGIKQLGRDAVGEAAASGELRKNAVVSAEVIGVNDGGIEVRLVNHEDVTAFIRRADLSRDRDEQRPERFSVGQTVDARVTNFSKKDRKIQLSIKALEIAEEKEAVAQFGSSDSGASLGDILGAALKNRQNNE
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: Y056_RUEST
Sequence: MNETTPAFDRHMLEALVCPVTQTVLEYDAEAQELVSRAANLAFPIRNGIPVMLTDEARPLE
What are the official names of this protein?
UPF0434 protein TM1040_0056.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: TIM16_XENTR
Sequence: MAKYLAQIMVMGMQVVGRAFTRALRQEFAASRAAAEARGRAGTESAAVSSLSGISLQEAQQILNVSKLTPEEIQKNYEHLFKVNDKEVGGSFYLQSKVVRAKERLDQEMDIQSKTEKPKDETTQT
What is the function of this protein?
Regulates ATP-dependent protein translocation into the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim16, Presequence translocated-associated motor subunit pam16.
What is the protein family that this protein belongs to?
Belongs to the TIM16/PAM16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL4_ONYPE
Sequence: MPKINILNQQGDFVSEKVLATTVFDIKPNQQVLYDVVNAQRAAMRQGTHATKTRALVAGGGKKPWRQKGTGRARHGSIRSPLWRGGGVTFGPSPRDYSVKVNQKVRSLALKSALSLQAKNNQLVVVDNINLATHKTKDFQQMLQKLNITSKSLIVVTQMTEQLALASRNLSYITLETASHASVYQILNCKQLVLTAAAVNYFEEVLK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: NDOR1_EMENI
Sequence: MSGSQSSGSPGSPGPPGPPGRSALVVYGSETGNAQDVAEEVGALAERLHFTTQISELNHVKPESLRSYTIVVFAVSTTGQGDLPANARTFWRSLLLKKLPPTFLSGVRFTWFGLGDSSYPKFNWAARKLYKRLLQLGADEIYPGGEADHQHSSGLEGTFIPWLAGFRKHLLDKYPLPPGQDPIPDDVQLPPKWVLRLRDQEAASEDVSPPDAMGAAVTGDFPDSYRLDNDHRPLHDSLTATLVQNKRVTPQTHWQDVRHLILTVSDPISYAPGDVLTITPKNTAEDVQSLIEMMGWQEQADQLVSLVPRDSTRSTNELPSPPIHSLDSYPRLTLRELLINYLDIRAIPRRSFFAAIAHYTTYEMHKERLLEFTNPEYLDEFWDYTTRPRRSILEILHEFDTVKIPWQHATSTFPIIRARQFSIASGGELKRTSVGGARFELLIAIVKYRTVIKKIREGVCTKYISNLRPGSTLKIQLQRGGLNSSVGQLVGPTMLIGPGTGVAPLRSMLWEKAAIVKSYQEKNPGVDPPIEPTILVYGGRNRAADFFFEDEWQQLSDLIKLKVLTAFSRDQKQKVYVQDVIRENSSLVFNLLHDKGGAVFVCGSSGRMPQAVRETLTEAFQYGNDAGTQPFSRREAEDYLVGMEKTGRYKQETW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of dre2, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  Positively controls H(2)O(2)-induced cell death.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: C1QT6_RAT
Sequence: MRVIMGTASLGSIWAVFLLPLVFGVPTEEPTFGESVASHLPKNCQRCCDPEDPLSPADTVNAVPPYVLPEVRPYINITILKGDKGDRGPSGTPGKPGKNGTRGDRGSQGIKGDKGQAGSPGSSCQTHYSAFSVGRKTGLHSSENFLSLLFDRVFVNTDGHFDMATGRFVAPLRGLYFFSLNVHSWNYKETYVHIVHNEQAVVILYAQPSERSIMQSQSVMLPLVPGDYVWVRLFKRERENGIYSDDMDTYITFSGHLIKAEDN
What are the official names of this protein?
Complement C1q tumor necrosis factor-related protein 6.
What are the subcellular locations of this protein?
Secreted.
Protein: NU4M_DICDI
Sequence: MTIIAISIMNVVIGIAILGVILRKKIMPNQKFQRIFILGVQGILIVLSGIMLIGCEGTDIINRISPYINMVTVYSNNVNINIGYSIDGISAIFIFLTIILILSCNLISIRVIKEKTEQKFQIMLLLTEILIINFFAATDLVQLYIVYEATLIPMVIMIGVWGSRTEKKIAAFQILIYTLIGSIFMLMSIGILYSTLGTTDYIMIREYIDVLPENVRKLIFIGFFIGFAVKIPIAPLHLWLLRAHVEAPTAGSVLLAGILLKLGGYGYIRYNIGLFPDLCEYYFPIIGGICLISILYTGIATLTQLDVKRIVAYSSISHMNVIVLGLFSGVLQGIEGGIILMIGHGVVSGGLFLCIGVIYDRCKTRIVYAYNNLVHVMPIMAILFFLLVLGNIAFPITSNFVGELLIFIGLIKKNIIIAFFSALSMIVTAIYSFWLYNRIFFVNEIIKREANEVISSKGQIVADMNALFLIEDVMKKKEERGIDDIGQPKEVKKEQLIYSDVNIFEFTSISLMVIMMIIIGMKPSVVEGFIAINCLELISK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SECB_ORITI
Sequence: MVATSKPKSEPKIAVKAQYVKDLSFENPDPINSLFKITEKPKIDTKLDINITKLSEDNHFEVELSTNVSATCNDKKIFHIEVVYAGIFQLTNISEEDKKFILSVRCPEIIFPYVRQIISESTQKGGFLPLMIDYIDFAEIISNTQTTNNQQELIKPEFDVSNKQ
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_BORBR
Sequence: MPTPLPSSSAWLAFADAARHSSRRGARLRVIEAAGLRVDLTAQAHSDDLDSAAEDLLAQQDFDNARAQLFDGGPANWTEHRPAWHTALRAARPPTPVAGAILGERDRLRRFVQDADMRGAYRHVLHLGIGGSDWGPRMVTRALRHNGLKREVRFASNVDSHAVADALHHLDPHDTLIIVASKSFTTTEPLANAEVAMNWLRNAGVADPVRQVVAITANVDAALDFGISPQHIFRFWDWVGGRYSLWSAIGLPVALALGCDALDELLAGAAAMDQHFLHTPMRRNAPLQMALAGVANRSVLGYGSLAITPYDSRLTHLVPWAQQLEMESLGKVAGHDGSPAGVPTGPVVWGMTGTDCQHTFFQWLHQDTAGAPVDFIVCEQADHPYDHFHKLLIANCLAQRAALLRGKPFDEALKEARLVESDPQQAEILAHHRVHPGGRPSTLIMLPRLSAHALGALLAMYEHKVFAQGVLWGINPFDQWGVEYGKALARNIIRELENPSSEVNQQDPSTRYWIDALRKQP
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTDB_ECOLI
Sequence: MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELKRPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGKGGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEFGPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK
What are the official names of this protein?
L(+)-tartrate dehydratase subunit beta, L-TTD beta.
What is the protein family that this protein belongs to?
Belongs to the class-I fumarase family.
Protein: DFBC7_BOVIN
Sequence: LALLFLVLSAGSGISGPLSCRRKGGICILIRCPGPMRQIGTCFGRPVKCCRSW
What is the function of this protein?
Has bactericidal activity.
What are the official names of this protein?
Beta-defensin C7, BBD(C7).
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: METXA_HALVD
Sequence: MSRTRTTPGRRVESDVVDIGEHEFESGEILPDLKVAYEAYGEFDGQNAVLVCHGLTGSQHVAGHGTESGVSGQARAWWGDIVGPGKAIDTNDYYVICVNVPGSCYGTSGPASEGPDGEPWGTDFPPVTVHDWTRAQRRLLDHLGVGRLHAVVGGSVGGMNALDWAVQFPDDVERLAVVASAARLDSQCLGIDAVARRAITSDPNWNGGDYYGEERPSPDAGLGLARQLGHLMYLSKDSMERKFGRRSAGRGERGDAFPSDPAASFFPYREVESYLDYQAEKFAERFDANAYLYLTRAMDDFDLSEGYESDAAALAAFEGEALLVSFTGDWHFTTEQSESLAGAFRRGDVPVAHHVVESDHGHDAFLVEPEKVGPPLADFVDEGVAGRAVTDTAPDGGEPDEDEDFAPVHSSLFSR
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTME_ASPFU
Sequence: MERLPLSPAVLFLIIVLPILYLWIRYTAPARPHGKHLSLPPGPPRLPKIGNLHQVPRQIPWKKYKEWSDTYGPIMSVQLADTIAVVFSSWDLIKNHIERRNTIYSSRPSVPFFLHATGGLNASILPYGPEWKLQRAIRSSVLKPSMTVKYRDVQHVETTQLLHELLSTNDFPVCLRRCIASVFLTVAYGERCVDHAGLEAIDRLEELNRAIALHAEALFSGAAGILTQLVLPKALVDRLPVRWKKDADMLHNRLTADLVARTRAALVRPGWNWVKEFSMKDGIGSGDGDGEQGSKVELKRLAYMVGSLYEASMAASQALRVIILAGLLHPDATRRMHDELDAVVGTGRLPDFHDAAQLPYTQAFIKEAMRWRSLTPMGSPRATSDEDECRGYHIPCGATVLVNVWAINHDEAIFLDPFAFQPERWIENPDLPQLMYGMGQRACPGRHMGQDSLFLATARLFWAFDMALPDGADPIDQERFLDSGTTLAAFLPDFEVRFTPRSEKYQEVIENSMAVLPDVLSISATP
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of fumitremorgins, indole alkaloids that carry not only intriguing chemical structures, but also interesting biological and pharmacological activities (PubMed:19226505, PubMed:23649274).  The biosynthesis of fumitremorgin-type alkaloids begins by condensation of the two amino acids L-tryptophan and L-proline to brevianamide F, catalyzed by the non-ribosomal peptide synthetase ftmA (PubMed:16755625).  Brevianamide F is then prenylated by the prenyltransferase ftmPT1/ftmB in the presence of dimethylallyl diphosphate, resulting in the formation of tryprostatin B (PubMed:16000710, PubMed:21105662, PubMed:23090579).  The three cytochrome P450 monooxygenases, ftmP450-1/ftmC, ftmP450-2/ftmE and ftmP450-3/FtmG, are responsible for the conversion of tryprostatin B to 6-hydroxytryprostatin B, tryprostatin A to fumitremorgin C and fumitremorgin C to 12,13-dihydroxyfumitremorgin C, respectively (PubMed:19226505).  The putative methyltransferase ftmMT/ftmD is expected for the conversion of 6-hydroxytryprostatin B to tryprostatin A (Probable).  FtmPT2/FtmH catalyzes the prenylation of 12,13-dihydroxyfumitre-morgin C in the presence of dimethylallyl diphosphate, resulting in the formation of fumitremorgin B (PubMed:18683158).  Fumitremorgin B is further converted to verruculogen by ftmOx1/ftmF via the insertion of an endoperoxide bond between the two prenyl moieties (PubMed:19763315).  In some fungal species, verruculogen is further converted to fumitremorgin A, but the enzymes involved in this step have not been identified yet (Probable).
What are the official names of this protein?
Fumitremorgin C synthase, Cytochrome P450 monooxygenase ftmP450-2, Fumitremorgin biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DRC10_HUMAN
Sequence: MALDILAMAPLYQAPAINRIGPKTDPSKRPADPLKPLVLSRTKLTTIEAKRIMSILDEAIYKVELVTLLSYVASNREDMEGMLGEDVMRAVREHEDLCQVLLENVRCLKEKERQLQEQKEAEEEGWLRDRLLSIELQKSSLSPLMQQIKDSTKNVLRLLLSNPQAARLLQMQTQGRSAEAQNFIDSLIELRGFLFEKLLTSPMEARDKAQFLQDISRQNSNNQQIIDTLEKELAERMKNRNAEVEKENFVIQELKNHLHQVLKFSENSLVRTKQEAEKQQKADFRASQARVAKIQQEILQLQSQFYNLVMENREAEQALRKKKYKVETEIENWIQKYDTEMGEKQEELEDLDAVHREEKISLEELRRRHKVLVGEFAQIREEREINSKKRMEAEQEMVRMVRAATLIQALWKGYLVRSLLRSKKKRGKGKAKDKEKGKQKGKEKGKGKK
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
What are the official names of this protein?
Dynein regulatory complex protein 10, IQ domain-containing protein D.
What is the protein family that this protein belongs to?
Belongs to the DRC10 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: ASNA_PASMU
Sequence: MKKSFILQQQEISFAKNTFTEKLAEHLGIVEVQGPILSQVGNGIQDNLSGAEKAVQVNVKQITDATFEVVHSLAKWKRHTLARFNFAQGEGLFVHMTALRPDEDSLDQTHSVYVDQWDWEKVISAEQRNLAYLKETVRAIYAAILETEEAVSKKFGLATFLPKDIQFVHSEELVQRFPNMNDKERENAICKEYGAVFLIGIGGKLSDGKPHDVRAPDYDDWTTPSEGEYKGLNGDILVWNPILERAFELSSMGIRVDETALRKQLALTNNEDRLKFDWHQDLVNGRLPLSIGGGIGRSRLVMLLLQKKHIGEVQSSVWPKWVMEQFDNIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHO_DEIRA
Sequence: MTVTEVAPQALPFQELQEKILPELHLLAAGLGIENYRKLKKDALALAIMEKQADAEGQSLARGYLDITSDGYGFLQADLLDPASRSVLVTAGVIKQYHLRTGDEVIGRARKPRENERYGSLVRVEAVNGLDPEAARQRPRFDDLTPTFPDQQLVLEDPSTDDGLSLRVVDLLVPIGRGQRALIVAPPKAGKTTLLKKIANSITKNYPDVTVMVLLVDERPEEVTDFRESVQGAQVIASTFDEPPQHHVRVAEFVHERARRIVEEGGHVVILLDSITRLARANNLVTPPTGRTLSGGLDSNALHWPKRFLGAARNIREGGSLTILATALVETGSRMDDVIFEEFKGTGNAELVLSRRLEERRIFPALDILKSGTRREELLLQPEVLKKMWLLRKVISDMDPADAMEMLLGRMGKTRNNVEFLAALAG
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: RL5_LEGPH
Sequence: MIEMARLKEFYKKDVVTMMMKRFNYSSVMEVPRILKITLNMGVGEAVGDKKVMNHAIEDMTLISGQKPVVTKARKSIAGFKIREGWPIGCKVTLRRERMYEFLDRLISITLPRVRDFRGLNPKSFDGTGNYSMGIHEQIVFPEIDYDKTDGIRGLDICITTSAKTNEEAKALLEAFNLPLKDKDRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: IF3_XANCP
Sequence: MPLGDCNISTPDNKQNRKNQEIRVPRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKKANEAKKKTKQVEIKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQELGREMAARIEADLGEDIVIESRPRLEGRQMVMMIAPKKKI
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABV_IDILO
Sequence: MIIKPKIRGFICTNSHPVGCAENVKRQIEFVRNKPAITNGPKNVLVIGCSTGYGLASRITAAFGSEAHTLGVCFEKEPTEKKTATAGWYNTAAFHQEANKAGLAFHSINGDAFSDEIKQESIDYIKQNMGKIDLVVYSLASPKRKDPDSGEVYSSVLKPIGKQYTTKTYNTDKDQVHEVTLDPATDEDIANTVKVMGGEDWERWVKALHNAGVLAENCQTTAYTYIGKKLTLPIYGHATIGRAKEDLDRAASELVAECDDLNLKAYVSSLKALVTQASSAIPVMPLYISLIYKVMKEEGTHEGCIEQIYRLFTEGLYNSNPELDEAGRLHMDGYETNDKTQAKIEALWEQVTQDNFHQLADYEGYHQEFLHLFGFGFDNVDYDADIDPKVNW
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: TUSB_ECOLU
Sequence: MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYLESLRNAPIKVYALNEDLIARGLTGQISNDIIPIDYTDFVRLTVKHSSQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB2_RHOPB
Sequence: MREIIQGLLFVALGSVFGGMARFWLSGMVARRIGETFPWGTLTVNVSGAFAIGVFGALAASGHGVFSTPGPWLFAVTGFLGCYTTVSSFALQTLALARDGESLRAISNVTFSLVFCLIAVALGFAAARVLA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: USB1_HUMAN
Sequence: MSAAPLVGYSSSGSEDESEDGMRTRPGDGSHRRGQSPLPRQRFPVPDSVLNMFPGTEEGPEDDSTKHGGRVRTFPHERGNWATHVYVPYEAKEEFLDLLDVLLPHAQTYVPRLVRMKVFHLSLSQSVVLRHHWILPFVQALKARMTSFHRFFFTANQVKIYTNQEKTRTFIGLEVTSGHAQFLDLVSEVDRVMEEFNLTTFYQDPSFHLSLAWCVGDARLQLEGQCLQELQAIVDGFEDAEVLLRVHTEQVRCKSGNKFFSMPLK
What is the function of this protein?
3'-5' RNA exonuclease that trims the 3' end of oligo(U) and oligo(A) tracts of the pre-U6 small nuclear RNA (snRNA) molecule, leading to the formation of a mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate (PubMed:23022480, PubMed:22899009, PubMed:26213367, PubMed:31832688, PubMed:23190533, PubMed:28887445, PubMed:30215753).  Participates in the U6 snRNA 3' end processing that prevents U6 snRNA degradation (PubMed:23022480, PubMed:22899009, PubMed:26213367, PubMed:31832688, PubMed:23190533, PubMed:28887445, PubMed:30215753).  In addition also removes uridines from the 3' end of U6atac snRNA and possibly the vault RNA VTRNA1-1 (PubMed:26213367).
What are the official names of this protein?
U6 snRNA phosphodiesterase 1, hUsb1, 3'-5' RNA exonuclease USB1, Mutated in poikiloderma with neutropenia protein 1, Mutated in PN protein 1, hMpn1.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. USB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS8_LATSS
Sequence: MVMTDPIADYLTRIRNANMVRHESLEVPASRIKKDISEILKREGFIRDYEVIEDDKQGIIRVFLKYGKNNERVISGLKRISKPGLRNYVKANEVPKVLNGLGIAIISTSNGVVTDKEAREKAAGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CATA1_GOSHI
Sequence: MDPYKHRPSSAFNSPFWTTNSGAPVWNNNSSLTVGPRGQYLLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFIRDGMKFPDMVHALKPNPKSHIQENWRILDFFSHHPESLHMFTFLFDDLGVPQDYRHMEGSGVNTYTLINKAGKAHYVKFHWKPTCGVKCLLEDEAIKVGGANHSHATQDLYDSIAAGNYPEWKLFIQTIDPDHEDKFDFDPLDVTKTWPEDILPLQPVGRLVLNKNIDNFFAENEQLAFCPAIVVPGIYYSDDKLLQTRIFSYSDTQRHRLGPNYLQLPANAPKCAHHNNHHEGFMNFMHRDEEINYFPSRYDPVRHAEMFPIPPAVCTGRREKCIIEKENNFKQPGERYRSWAADRQERFICRWVDALSDPRVTHEIRSIWISYWSQADKSVGQKLASLLNVRPSI
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 1.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MTFA_KLEP3
Sequence: MFKWPWKADDESGNAEMPWEQALAIPVLAHLSPTEQRKLTQLAARFLQQKRLVALQGLELTPLHQARIALLFCLPVLELGIEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRVVQSGQSWQQGPVVLNWLDIQDSFDASGFNLVVHEVAHKLDARNGDRASGVPLIPLREVAGWEHDLHAAMNNIQDEIDMVGESAASIDAYAATDPAECFAVLSEYFFSAPELFAPRFPALWQRFCHFYQQDPLQRIRENGLQDEDNRRIVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIQJ_DICDI
Sequence: MQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin-J.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HSP1_PETCN
Sequence: MARYRHSRSRSRSRYRRRRRRRSRYRSRRRRXRRRRRSRRGRRRRGYSRRRYSRRRRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.