PharMolix/UniProtQA huggingface dataset:
Protein: RB_HUMAN
Sequence: MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTELQKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSSISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFMNSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKSNLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAEMTSTRTRMQKQKMNDSMDTSNKEEK
What is the function of this protein?
(Microbial infection) In case of viral infections, interactions with SV40 large T antigen, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity.
What are the official names of this protein?
Retinoblastoma-associated protein, p105-Rb, p110-RB1, pRb, Rb, pp110.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
Protein: HVM50_MOUSE
Sequence: QVQLLQPGTELVKPGASVNLSCKASGYTFTSYWMHWIRQRPGQGLEWIGGINPSNGGTNYNEKFKSKATLTVDKSSSATYMQLSTPTSEDSAVYYCARWDYEGDRYFDVWGTGTTVTVSS
What are the official names of this protein?
Ig heavy chain V region AC38 15.3.
Protein: MATRX_SENDF
Sequence: MADIYRFPKFSYEDNGTVEPLPLRTGPDKKAIPYIRIIKVGDPPKHGVRYLDLLLLGFFETPKQTTNLGSVSDLTEPTSYSICGSGSLPIGVAKYYGTDQELLKACTDLRITVRRTVRAGEMIVYMVDSIGAPLLPWSGRLRQGMIFNANKVALAPQCLPVDKDIRFRVVFVNGTSLGAITIAKIPKTLADLALPNSISVNLLVTLKTGISTEQKGVLPVLDDQGEKKLNFMVHLGLIRRKVGKIYSVEYCKSKIERMRLIFSLGLIGGISFHVQVTGTLSKTFMSQLAWKRAVCFPLMDVNPHMNLVIWAASVEITGVDAVFQPAIPRDFRYYPNVVAKNIGRIRKL
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Forms a shell at the inner face of the plasma membrane and concentrates the HN and F glycoproteins.  Acts as a negative regulator for transcription and replication by sticking to the nucleocapsid.  This effect might be regulated by the cytoplasmic interaction with tubulin that dissociates the M protein from the nucleocapsid (By similarity).
What are the official names of this protein?
Matrix protein, M protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=During bud formation, associates at the inner side of the plasma membrane of infected cells.
Protein: CPL5_ARATH
Sequence: MFVAKNLSPERESKRQKKEPEIMEPSFPLLSPNNCGHWYIRYGFCIVCKSTVDKTIEGRVFDGLHLSSEALALTKRLITKFSCLNMKKLHLVLDLDLTLIHSVRVPCLSEAEKYLIEEAGSTTREDLWKMKVRGDPISITIEHLVKLRPFLCEFLKEANEMFTMYVYTKGTRPYAEAILKLIDPKKLYFGHRVITRNESPHTKTLDMVLADERGVVIVDDTRKAWPNNKSNLVLIGRYNYFRSQSRVLKPHSEEKTDESENNGGLANVLKLLKGIHHKFFKVEEEVESQDVRLTMSVVENFSSEPKAKRRKIEPTINESSSSLSSSSSCGHWYICHGICIGCKSTVKKSQGRAFDYIFDGLQLSHEAVALTKCFTTKLSCLNEKKLHLVLDLDHTLLHTVMVPSLSQAEKYLIEEAGSATRDDLWKIKAVGDPMEFLTKLRPFLRDFLKEANEFFTMYVYTKGSRVYAKQVLELIDPKKLYFGDRVITKTESPHMKTLDFVLAEERGVVIVDDTRNVWPDHKSNLVDISKYSYFRLKGQDSMPYSEEKTDESESEGGLANVLKLLKEVHQRFFRVEEELESKDVRSLLQEIDFELNVESVE
What is the function of this protein?
Mediates the dephosphorylation of 'Ser-2' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).  This promotes the activity of RNA polymerase II.  Regulates positively abscisic acid (ABA) and drought responses, including the regulation of specific genes expression.
What are the official names of this protein?
RNA polymerase II C-terminal domain phosphatase-like 5, FCP-like 5, Carboxyl-terminal phosphatase-like 5, AtCPL5, CTD phosphatase-like 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_CALJA
Sequence: MTSPRKTHPLAKIINESFVDLPTPSNISSWWNFGSLLGTCLIIQITTGLFLAMHYTPDTATAFSSVAHITRDVNYGWMIRYLHANGASMFFICLFLHVGRGLYYGSFLFLKTWNIGTILLLATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVQWIWGGFSVDKATLTRFFTFHFILPFIIAALATIHLLFLHETGSSNPSGITSEPDKVPFHPYYTTKDILGLTFLLLALTSLTLFTPDLLTDPDNYTLANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAMSILVLMIIPMTHMSKQQSMAFRPITQIMFWTLVADLLTLTWIGGQPVEHPFIAIGQTASIMYFLIIITLIPLSALIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NIFH_METAR
Sequence: MRQVAIYGKGGIGKSTTTQNTVAALAESGKKVMVVGCDPKADSTRLLLHGLNQKTVLDTLRDEGDDIELESILKTGFGETRCVESGGPEPGVGCAGRGIITSINMLEQLGAYTDDLDYVFYDVLGDVVCGGFAMPIREGKAREIYIVASGELMALYAANNIAKGIKKYAETGGVRLGGIICNSRKADNEYALVKAVAEEIGTQMIHFVPRDNIVQRAEINKMTVIDFDPAANQANEYRKLAKAIDENQMFVVPKPMTQDRLEELMMKHGFLDAV
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: CD8B_MOUSE
Sequence: MQPWLWLVFSMKLAALWSSSALIQTPSSLLVQTNHTAKMSCEVKSISKLTSIYWLRERQDPKDKYFEFLASWSSSKGVLYGESVDKKRNIILESSDSRRPFLSIMNVKPEDSDFYFCATVGSPKMVFGTGTKLTVVDVLPTTAPTKKTTLKMKKKKQCPFPHPETQKGLTCSLTTLSLLVVCILLLLAFLGVAVYFYCVRRRARIHFMKQFHK
What is the function of this protein?
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.  In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex.  The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins.  Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs).  In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.  A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.  Once LCK recruited, it initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs).  Additionally, plays a critical role in thymic selection of CD8+ T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD8 beta chain, Lymphocyte antigen 3, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein Lyt-3.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Note=Requires the partner CD8A for efficient cell surface expression. The heterodimer CD8A/CD8B localizes to lipid rafts due to CD8B cytoplasmic tail palmitoylation.
Protein: RSMI_BUCAP
Sequence: MNSLNKTGLLYIVPTPIGNLSDITYRAVETLKNVNLIAAENIHHTNILLQHYNVKNILISLNKNNEKKQSDYVINELKKGKKIALVSDAGTPVINDPGYFLVKKCCFLNIKIIPLPGPCAAITALSASGISTNRFCYEGFLPSKKKIRRDLLKSLKKEIRTIIFYESKHRILESIKDIIETIDENRYLVIAREITKKWEYIYGAKANIILSWLKEDQSRYKKGEIVIIIDGFKELKNKDISAKAINTLTILRNFLSLKQSVFITSKIHKIKKNDLYQHAIKEKDK
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEX_SALSV
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRMLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYA_BRUME
Sequence: MAGVNEIRSTFLDYFRKNGHEVVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGLEHRSYNRATTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEDAISFAWNLITREFGLPKDKLLVTVYHTDDDAANFWKKIAGLSDDRIIRIPTSDNFWAMGDTGPCGPCSEIFYDHGDHIWGGPPGSPEEDGDRFIEIWNLVFMQFEQQTPELRIDLPRPSIDTGMGLERIAAVLQGVHDNYDIDLFKALIRASEEATGVKAEGDFRASHRVIADHLRASSFLIADGVLPSNEGRGYVLRRIMRRAMRHAQLLGAKEPLMWRLLPALIREMGQAYPELIRAESLISETLKLEETRFRKTLERGLGLLSDASENLAEGDRLDGETAFKLYDTYGFPLDLTQDALRQRGIAVDTEGFNVAMERQKAEARANWTGSGEAATETIWFGIKDKVGATEFLGYETESAEGVIASLVRDGVEVPSVREGETISVVVNQTPFYGESGGQQGDTGTISGEGFVIAVKDTQKKGEGVFVHIGEVTEGTAKAGDVVELKVDSARRTRIRSNHSATHLLHEALRETLGTHVAQKGSLVAPDRLRFDFSHPKPISAEELEAVENLANEIILQNAPVTTRLMAVDDAIAEGAMALFGEKYGDEVRVVSMGTAKHGSKAGKAYSVELCGGTHVRQTGDIGLVRIISEGGVAAGVRRLEALTGEAARLYLEEQDERVKAIASALKTTSADVLDRVNALIDERKKLERELADARKKLALGGGSSDGGSAVEAVNGVNFLGKIVTGVSPRDLKPLADEGKKQVGSGVVLFIGVGEDGKASAVAAVTEDMVGRFSAVDLVRAASAALGGAGGGGRPDMAQAGGPDGAKAADAIAAVKALIA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHIT_STRVO
Sequence: GDGTGPGPGP
What is the function of this protein?
Has antifungal activity.  Inhibits mycelial growth of wood rotting fungi P. chrysosporium MTCC 787, S. commune ITCC 3751, G. trabeum MTCC 355, P. agaricans ITCC 761, C. versicolor MTCC 138, P. versicolor ITCC 13, P. placenta MTCC 144 and P. friabilis ITCC 335.
What are the official names of this protein?
Chitinase.
What are the subcellular locations of this protein?
Secreted.
Protein: PURR_ACTPJ
Sequence: MATIKDVAKLAGVSTTTVSHVINKTRFVAEDTSKAVWDAIQQLNYSPSAVARSLKVNTTKSIGMIITTSEAPYFAEIVLAVEEHCYQQGYSLFLCNTQNEPEKIQNHLDMLIKKRVDGVLVMCSEYTRDSLELFNGTNIPMVVMDWGKADDHSDRILDNSFEGGYLATQHLIENGHKDIGVIAGHLSKTLSKERYEGFLKAMHEANLPVRQEWIYEGDFEPESGFEQMNNLLRLEKLPTAIFCFSDTIALGAISALSEKGLSVPSDMSIIGYDNIHSSRFYSPPLTTIHQSKSRLGVKALNILLERIKIDKTQYQPQTIEFHPELVLRRSVRNLNK
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: DRO1_ORYSJ
Sequence: MKIFSWVANKISGKQEANRFPANSSAPYRANVSDCRKDEFSDWPQSLLAIGTFGNKQIEEVAQVENSSDNVQSVQDTVKFTEEEVDKIRKEFETLLAIKDQAEAQRSHDDDQVGLQKRADGEDNEKHIRQLINKRIIVSKSKNSLGKKGNTLKPRSVASLLKLFMCKGGFTSVVPEPRNTFPQSRMEKLLKAILQKKIHPQNSSTLVAKRHLDWKPDETEINECLEDALRDLDDDGAKWVKTDSEYIVLEM
What is the function of this protein?
Involved in the control of root growth angle (PubMed:23913002).  Involved in cell elongation in the root tip that causes asymmetric root growth and downward bending of the root in response to gravity (PubMed:23913002).
What are the official names of this protein?
Protein DEEPER ROOTING 1, Protein NEGATIVE GRAVITROPIC RESPONSE OF ROOTS 3, OsNGR3.
What is the protein family that this protein belongs to?
Belongs to the LAZY family.
Protein: U4_FBNY1
Sequence: MEVRFLLFLLLLVLVINPSLVVNMVFGYMFGLLLRNNYSRLKAMIRSNQTEEEEERHEAVDVSNPFEDVDIDVMQHLKTLGLDSKVDEEDVEYFRRFWQSMLRNK
What are the official names of this protein?
Protein U4.
What is the protein family that this protein belongs to?
Belongs to the nanovirus U4 protein family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RR11_HETA4
Sequence: MIKQIKRKKVKKNVVVGVVHIQASFNNTIVTITDLGGNTLSTGSAGAVGFKGARKGTPFAAQLASEKAAEKATEYGLKKVEVLVKGQGSGRETAVRAIQNSDIEITAITDITSIPFNGCRPPKRRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KLHL7_HUMAN
Sequence: MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.  The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins.  Probably mediates 'Lys-48'-linked ubiquitination.
What are the official names of this protein?
Kelch-like protein 7.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with CUL3 in punctate structures at the perinuclear region of the cytoplasm.
Protein: CO8B_PAROL
Sequence: MFRVAIPRSALNLHSCLLHVTLSLVLISKAAITTAGNEDSDVREARSVSDQQVVHPVDCVISDWSAWSRCDTCQKKRYRYAKLDQPSQFGGEPCHFHDMEDEACDVPDRYTCDSIPLCEGFLCTQTGRCIHRTLQCNGEDDCGDMSDEVGCKKVPKPCRQEAEEYWGIENLAKGINILNSNLEGLVLDNRYYAGSCLPQYIQDVRFRKPHNLQQYTLETKGSYDFNVQSFESYSDYMDYSMRERMTQTIVSIGFAIPGIAEFGFNYNNAKVTRSIQKIRRASSKINSFVSAKAELELAQYMLRSDDLMLHPEFLQRLRSLPQAYVYGEYRQIYRDYGTHYITEAALGGEYEHTIILDKEKLAKTDYSLEDYKSCTQAGLKIGANIYGVYVSAGIEGGSCNGLLNEMGEDTAIGSSVEDFVAVVRGGSSESITGLVSKKLPTPQLMRLWGEGVRFNPDFIRKTTRPLYELVTSKDFSHDATLKRNLKRALSEYLAESSSCRCAPCHNNGVAVLRGTRCDCVCPTGYTGRGCEITQRKKQIATDGSWSCWGAWSSCSGRKMSRSRQCNNPVPSDGGLACRGLQQESTDCF
What is the function of this protein?
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
What are the official names of this protein?
Complement component C8 beta chain, Complement component 8 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the complement C6/C7/C8/C9 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF2_ECO8A
Sequence: MFEINPVNNCIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAELDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHA_CAUVC
Sequence: MADAAAPNASSMPSAKSLLDGLMRGEMGLALGVVGIIVLLIIPVPAPLLDVLLAISLTGSVLILMTAILIKKPLEFTSFPTVLLVTTLFRLGLNIASTRLILSHGQEGTGGAGAVIEAFGHLMMQGNFVIGVIVFIILIVVNFMVVTKGSGRIAEVAARFTLDSMPGKQMAIDADLSTGLISQDEAKIRRKELEQESTFFGAMDGASKFVKGDAIAGLIITAINIIGGIIIGVVQHKMPFGDAASTYTIMTIGDGLVSQIPALIISIAAGMVVSKAGVEGSADKALTTQLAMNPVGLGMVSASSGIIALIPGMPIFPFAAMALAAGALAYKRVQDAKKPKALDPADLEAAAPSEPEEEPISASLAIDDVKIELGYGLLTLINDLDGRKLTDQIRALRKTLASEYGFVMPPVRILDNMRLANQGYAIRIKEMEAGAGEVRLGCLMCMDPRGGQVELPGEHVREPAFGLPATWIADDLREEATFRGYTVVDPATVLTTHLTEILKENMADLLSYAEVQKLLKELPETQKKLVDDLIPGTVTATTVQRVLQSLLRERVSIRDLPQILEGVGEAAPHTASVTQLVEQVRARLARQLCWANRGDDGALPIITLSADWEQAFAEALIGPGDDKQLALPPSRLQDFIRGVRDSFERAALAGEAPVLLTSPGVRPYVRSIIERFRGQTVVMSQNEIHPRARLKTVGMV
What is the function of this protein?
Required for formation of the rod structure of the flagellar apparatus.  Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity).
What are the official names of this protein?
Flagellar biosynthesis protein FlhA.
What is the protein family that this protein belongs to?
Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TDH_RHIL3
Sequence: MSNMMKALVKAKPEVGLWMENVPVPEVGPNDVLIRVKKSAICGTDVHIWNWDQWAQKTIPVPMVVGHEFSGEIAEIGSAVTRYHVGERVSGEGHIVCGKCRNCRAGRGHLCRNTLGVGVNRPGSFGEFVCIPESNVVPIPDDISDEIAAIFDPFGNAVHTALSFDLVGEDVLVTGAGPIGIMGALVAKRSGARKVVITDINPHRLELARKLGIDHVVDASKENLADVMKAIGMTEGFDVGLEMSGAAPAFRDMIDKMNNGGKIAILGIAPAGFEIDWNKVIFKMLNLKGIYGREMFETWYKMIAFVQGGLDLAPIITHRIGIDDFRDGFEAMRSGNSGKVVMDWM
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_DECAR
Sequence: MTVNLLDFDGESLTAWFAEQGEKPFRAKQVLRWIHRSGVADFDAMTDIAKSLREKLKAKAVVAPPAVVSDKLSDDGTRKFLIDVGNGNAVETVFIPEDDRGTLCISTQAGCALDCAFCSTGKQGFNRNLSVAEIIGQLWQANHALGAVHGDERVISNVVLMGMGEPLANFENSVAALKLMLDDNAYGLSRRRITVSTSGLVPVMDRLGDECPVALAVSLHAPNDKLRDQLVPINQKYPLKELMAACQRYLEKAPRDFITFEYIMLDGINDTDAHARELLALVKSVHCKFNLIPFNPFPGSPFRRSPAERVRHFADILMQAGIVTTTRKTRGDDIDAACGQLAGQVQDKTKRTTGRVIPLKEARS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y300_STRA5
Sequence: MKSTILVTGYKNFELGIFQDKDPRITIIKKAIDKDFRRFLENGADWFIFMGNLGFEYWALEVALDLQKEYDFQIATIFTFENHGQNWNEANKAKLALFKQVDFVKYTFPSYENPGQFKQYNHFLINNTQGAYLFYDSENETNLKFLLEMMEKKEAYDISFLTFDRLNEIYEE
What are the official names of this protein?
UPF0398 protein SAG0300.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: JANO_PENJA
Sequence: MTIPELPILWRDNAPPSEYEAWRSRTFNSKRPDAQPLAIIKPTTIDHIVSATALAKENNAKLALRSGGHSLQCWSLRKDSILVDLENFRYLEFDDATGVVSVTPSVTSSELLLFLANKKRFFPSGHSGEVGLGGFLLQGGIGLNARSYGYACEYLTAVDVVTVSGEVKHCSPDENADLFWAARGAGPEFPAIVTRFHLNTRPLLPTVKRCTYIWPAVCYEMVFKWVLEILPTLSDDIEPTIFGFTLPNTPIPVIAFHAHVHAESDESAIELLKPLHESHPAGAMVEQDCVDTSVQQEFESGHAIMPPGARYFTDSVFLTPGTDIIEACREMFTTLPAQAAGSIAYWEPMKQRTKLPEMAWSIHSEHYVSLMAIYGDQNQDHKQQTWILDCFKDMDRKGLLLGTYVGDAHPKDRPHHYWSDPAKERIQKIGVQWDPEARLRGTIFAENTL
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes janthitremanes such as shearinine K or shearinine A (PubMed:26213965).  The geranylgeranyl diphosphate (GGPP) synthase janG catalyzes the first step in janthitremane biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:26213965).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase janC then forms 3-geranylgeranylindole (3-GGI) (PubMed:26213965).  Epoxidation by the FAD-dependent monooxygenase janM leads to a epoxidized-GGI that is substrate of the terpene cyclase janB for cyclization to yield paspaline (PubMed:26213965).  Paspaline is subsequently converted to 13-desoxypaspaline by the cytochrome P450 monooxygenase janP, via beta-PC-M6 in a series of alpha-face oxidations (Probable).  The cytochrome P450 monooxygenase janQ is proposed to carry out sequential beta-face oxidation steps at C-7 and C-13 of 13-desoxypaspaline to form paspalicine and paspalinine respectively (Probable).  The indole diterpene prenyltransferase janD may then convert paspalinine into shearinine K which is substrate of janO and/or additional enzymes for oxidation and cyclization to generate shearinine A (Probable).
What are the official names of this protein?
FAD-linked oxidoreductase janO, Janthitremanes biosynthesis cluster protein O.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: IHFB_XYLFT
Sequence: MTKSELIEILTKRQAHLKSDDVDLAVKSLLEMMGGALSGGDRIEIRGFGSFSLHYRPPRCGRNPKTGESVALPGKYVPHFKPGKELRERVASVVPLGECGDITE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: SYT_LACH4
Sequence: MSFSITLPDGSKKDFEESLTIADLAQNIATSLGKAAVAGKVNGELKPLDYKLDSDSEVAIITNKDEEGLDVLRATAAFVFEAVAKCEYPELRLGEHVADEGGFYVDTDKDDQIKVGELPKLEKAMQKVIKNGEKIEHVQIAKSELEELYKNDKFKSELLAKVEGDTVDAYKLGDFVDFGFDALLPNTGKIKQFKLLSVAGAYWLGKSSNPMLQRIFGTAFFKEADLKADLKRRQEIKERDHRTIGRDLDLFFVDPKVGAGLPYWMPKGATIRRAVERYIIDREVADGYQHVYTPVLMNLDAYKTSGHWAHYRDDMFPPMDMGDGEMLELRPMNCPSHIQIFKHHIRSYRDLPLRVAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVALDQVQTEFAKILKLIMEVYKDFDITDYYFRLSYRDPKNTDKYFANDEMWEKSQKMLKGAMDDLGLDYVEAEGEAAFYGPKLDIQTKTALGNDETMSTIQLDFMLPDRFGLTYVGKDGEEHRPVMIHRGIVGTMERFIAYLTEIYKGAFPTWLAPVQAEIIPVNNEAHGEYAEKVRAELAKRGFRVEVDDRNEKMGYKIRESQTQKVPYTLVLGDEEMKSGKVNLRRYGTDEEISKSLDDFINEIDADVKSYSREN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_STRS7
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKINEDKQDFGFDRLAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDRIEELFHIPVSYQDERLTTVEAERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.