PharMolix/UniProtQA huggingface dataset:
Protein: TXD04_LYCSI
Sequence: MKILFVLISILYAVYCFSSEEDVDSAYLANELEPVEDINSEQYAALEPKEEQGRSCADMGQDCKDDCDCCLNIATCNCWFGRYFCSCTFGDYQTCLRKKGKCKRNRPQSCPRSNLNRKKG
What are the official names of this protein?
U13-lycotoxin-Ls1a, Toxin-like structure LSTX-L4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 05 (agouti) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RK22_SORBI
Sequence: MTSFKLVKYTPRIKKKKGLRKLARKVPTDRLLKFERVFKAQKRIHMSVFKAQRVLDEIRWRYYEETVMILNLMPYRASYPILKLVYSAAANATHYRDFDKTNLFITKAEVSRSTIMKKFRPRARGRSYSIKKTMCNITIVLNIVKKSK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PNKP_MIMIV
Sequence: MRYYRITIIRFINKYTKIMDWIESDSYLKGIINNKPKLHDPVRVASFDLDDTLIVRSKKTQKWKLVDSSIKQKIAELIENKYIIIVFTNQGGMSLNKKFDKPLWRKAMDDLVKILTSETDNDFYFAIYVAKKYDIYRKPNIGLWNLMKQDIKDEFNLDSVQISTKSFFCGDAAGRIYPSMFKKKLYPTSKGGDFSDTDRKFALNIGIKFLTPEEFYLDSKNSENLKTNYKLSGVNPTEIIDEIENTKLVNYKFKPRKKEMIVMIGQPGSGKSFFVKNYILPNGYVHINQDKCKTKAKCLSETENALSKGKSVVIDNTNPDVISRMTYTNLAKENNYDHVRAIIMETPDELAKHLNNVRHIYSSGTVPKVTDIAYNIYRKNFVLPQYEENFDKIETVTFYFDKSMLDDPKWKRSFMKFSEYK
What are the official names of this protein?
Putative bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the DNA 3' phosphatase family.
Protein: Y1584_STRS7
Sequence: MDIRQVRETVEMIEEQHFDIRTITMGISLLDCVDSDIDRAAAKIYQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLPLAKALDQAACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTKKVCASVNVGSTRSGINMTAVADMGRIIKETAKASEMGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGVVKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPAVGDSVARVLEEMGLEMVGTHGTAAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDEGMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKTTAVRIIPKGKEGDMIAFGGLLGTAPVMPVNPHSSLEFIARGGQIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein SZO_15840.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: TIF3_ORYSJ
Sequence: MDLLEKKNIKKGGEVEEEVARKGEERKEEEVVVEEKSHQQQQQQGEEELVGLSLAGGRPKVFPMSSPPPNPSQLTIFYGGSVCVYDSVPPEKAQAIMLIAAAAAAAASATKSNAAIAVKPPVMPAANATQAAVSPVLTRSLSLQSTSVATGQPQVAADPSSICKLQADLPIARRHSLQRFLEKRRDRLVSKAPYPTKSSEGMEASGMEVTAEGKAQ
What is the function of this protein?
Repressor of jasmonate responses negatively regulated by the proteasome in an SCF(COI1) E3 ubiquitin-protein ligase complex-dependent manner.  Involved in jasmonate (JA) signaling pathway during spikelet development.  Targets directly the transcription activator MYC2 and suppresses the activity of MYC2 in triggering the transcription of MADS1 (PubMed:24647160).
What are the official names of this protein?
Protein TIFY 3, OsTIFY3, Jasmonate ZIM domain-containing protein 1, OsJAZ1, OsJAZ10, Protein EXTRA GLUME 2.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2143_STAA8
Sequence: MTNGYIGSYTKKNGKGIYRFELNENQSRIDLLETGFELEASTYLVRNNEVLYGINKEGEQCGVASLKIDDNGELHLLNKCLSSKAGTGCYVSISEDKRYLFEAVYGAGIIRMYELNTHTGEIIRLIQELAHDFPTGTHERQDHPHAHYINQTPDGKYVAVTDLGADRIVTYKFDDNGFEFYKESLFKDSDGTRHIEFHDNGKFAYVVHELSNTVSVAEYNDGKFEELERHLTIPENFDGDTKLAAVRLSHDQQFLYVSNRGHDSIAIFKVLDNGQHLELVTITESGGQFPRDFNIASSDDLLVCAHEQGDSVVTVFERNKETGKITLCDNTRVASEGVCVIF
What are the official names of this protein?
Uncharacterized protein SAOUHSC_02143.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: HBBA_ANGAN
Sequence: VEWTEDERTAIKSKWLKINIEEIGPQAMRRLLIVCPWTQRHFANFGNLSTAAAIMNNDKVAKHGTTVMGGLDRAIQNMDDIKNAYRQLSVMHSEKLHVDPDNFRLLAEHITLCMAAKFGPTEFTADVQEAWQKFLMAVTSALARQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin anodic subunit beta, Hemoglobin anodic beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: T23O_BURP1
Sequence: MQPPGDDAAPRCPFAGAHAPDAPHVPEAAGDDAQAGWHRAQLDFSQSMSYGDYLSLDPILDAQHPRSPDHNEMLFIIQHQTSELWMKLALYELRAALASIRDDALPPAFKMLARVSRVLEQLVQAWNVLATMTPSEYSAMRPYLGASSGFQSYQYRELEFILGNKNAQMLRPHAHRPAIHAHLEASLQAPSLYDEVIRLLARRGFPIAPERLDADWTQPTRHDRTVEAAWLAVYREPNAHWELYEMAEELVDLEDAFRQWRFRHVTTVERIIGFKQGTGGTSGAPYLRKMLDVVLFPELWHVRTTL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: SLT1_CHLRE
Sequence: MAALSWQGIVAVTFTALAFVVMAADWVGPDITFTVLLAFLTAFDGQIVTVAKAAAGYGNTGLLTVVFLYWVAEGITQTGGLELIMNYVLGRSRSVHWALVRSMFPVMVLSAFLNNTPCVTFMIPILISWGRRCGVPIKKLLIPLSYAAVLGGTCTSIGTSTNLVIVGLQDARYAKSKQVDQAKFQIFDIAPYGVPYALWGFVFILLAQGFLLPGNSSRYAKDLLLAVRVLPSSSVVKKKLKDSGLLQQNGFDVTAIYRNGQLIKISDPSIVLDGGDILYVSGELDVVEFVGEEYGLALVNQEQELAAERPFGSGEEAVFSANGAAPYHKLVQAKLSKTSDLIGRTVREVSWQGRFGLIPVAIQRGNGREDGRLSDVVLAAGDVLLLDTTPFYDEDREDIKTNFDGKLHAVKDGAAKEFVIGVKVKKSAEVVGKTVSAAGLRGIPGLFVLSVDHADGTSVDSSDYLYKIQPDDTIWIAADVAAVGFLSKFPGLELVQQEQVDKTGTSILYRHLVQAAVSHKGPLVGKTVRDVRFRTLYNAAVVAVHRENARIPLKVQDIVLQGGDVLLISCHTNWADEHRHDKSFVLVQPVPDSSPPKRSRMIIGVLLATGMVLTQIIGGLKNKEYIHLWPCAVLTAALMLLTGCMNADQTRKAIMWDVYLTIAAAFGVSAALEGTGVAAKFANAIISIGKGAGGTGAALIAIYIATALLSELLTNNAAGAIMYPIAAIAGDALKITPKDTSVAIMLGASAGFVNPFSYQTNLMVYAAGNYSVREFAIVGAPFQVWLMIVAGFILVYRNQWHQVWIVSWICTAGIVLLPALYFLLPTRIQIKIDGFFERIAAVLNPKAALERRRSLRRQVSHTRTDDSGSSGSPLPAPKIVA
What is the function of this protein?
Na(+)/sulfate cotransporter with a probable high-affinity for sulfate and a proteasome dependent turnover.
What are the official names of this protein?
Sodium/sulfate cotransporter 1, SAC1-like transporter 1, CrSLT1.
What is the protein family that this protein belongs to?
Belongs to the divalent anion:Na+ symporter (DASS) superfamily. Na+/sulfate symporter (TC 2.A.47.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTND_SORC5
Sequence: MSRLRVYRESDPTRADEYTTLEDIARVAAEAQIRFERWSAERPLPPGAAQEQVLEAYAGPVKQLSEACGFVTADVVSVSPGTPNHPELRRKFLDEHIHTEDEARFFVEGRGLFCIHHGERVLSFLVEKGDLISVPAGTRHWFDMGPEPSFTCIRWFSDPKGWVAEHTGSDIASRFPRLEA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: HBB_POGSC
Sequence: VQWSESERTIINGIFSHLDYDDLGPKAFSRCLIVYPWTQRYFSSFGNLHNAEAIMGNANVAAHGIKVLHGLDLGLKHMDDIMGAYAELSSLHSEKLHVDPDNFKLLSDCIIIAVAAKLGNAFTPETQAAFHKFLAVVVSALGKQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MNTP_BIFAA
Sequence: MLIQILLIGVSVSMDTFAVSIGKGLTVKKLRGLDALKTALWFGGFQALFPLLGYFAASTFSKYVTAVDHWIIFGLLALIGGNMVREAFEEDEENAKETPEFDWKHMLPLAVACSIDAVAVGVSFAFMTLNIWLSVVIIGITTGLFSAAGLYIGRVFGSRWQKPAQIAGGVVLILIGLKVLFEHLGFLG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDHI_NICTO
Sequence: MLPMITEFINYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVINDYTIRTISNLPQIKNE
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: Y220_BACC1
Sequence: MDILLALLPAIAWGNILLVSVKMGGGAYSQTVGMTIGALFFATIMYVFTQPALTMTILIVGFISGLFWALGQVNQLKTVEKLGVSTTVTISTGMQLVATSIFGVIAFREWTTTTTIILGTIAILLIVVGVVFTSLDDKENAQPPGQLKKGLLTLIVSTFGYLVYVIIIRWYNIDGWSAILPQAVGMFVGAVVLTSKHKPFNKYAIRNALSGLLWGTGNLFLLLSLPRVGVATSFPLSQTGIVISTFGAIVFLGEKKTKRQLIFIALGSVLIIGGAVLLGMTKA
What are the official names of this protein?
Putative sugar uptake protein BCE_0220.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NS1_I47A0
Sequence: MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRRDQKSLKGRGSTLGLNIETATRVGKQIVERILKEESDEALKMTMASAPASRYLTDMTIEEMSRDWFMLMPKQKVAGPLCIRMDQAIMDKSIILKANFSVIFGRLETLILLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFA
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: HIS6_SHEHH
Sequence: MLAKRIVPCLDVKEGKVVKGVQFRNHEIVGDIVPLAKRYAEEGADELVFYDITASAHDRVIDKSWISRVAEKIDIPFCVAGGIRTIEQAREKLAFGADKISINSPALTDPSLIARLQDEFGRQCIVIGIDSYYDASSDSYRVKQFTGDEAATKDTQWYTQDWVEEVQKQGCGEIVLNVMNQDGVRQGYDIKQLSMIRSICDVPLIASGGAGTMAHFRDVFSRANVDAALAASVFHKGIIDIQELKQYLKDNQIAVRV
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP13_SCHPO
Sequence: MSYNGKDLGELQLKCHQSMLQAGAVFENCTFVNGDVLLEIPSFFIESLQFHYLINQSEKISLKLIFWNELVYLLGLNDTSKASATTSFQQGQIETKPDLTLFINELLTTKKEHKKLDNDNRESEIPFSDTRFHDEFDRESRACLHRSEFPKNPHAFLAQDLPHGLPHRRAALPCEALGFHPNVGDYFDWYPHRPNHFGGKFDGHSRGRGAGRGGFCGRHGRGGFGKRSGLHGCREEFWMQV
What are the official names of this protein?
Uncharacterized protein P4G3.03.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SNP47_HUMAN
Sequence: MRAARRGLHCAGAERPRRRGRLWDSSGVPQRQKRPGPWRTQTQEQMSRDVCIHTWPCTYYLEPKRRWVTGQLSLTSLSLRFMTDSTGEILVSFPLSSIVEIKKEASHFIFSSITILEKGHAKHWFSSLRPSRNVVFSIIEHFWRELLLSQPGAVADASVPRTRGEELTGLMAGSQKRLEDTARVLHHQGQQLDSVMRGLDKMESDLEVADRLLTELESPAWWPFSSKLWKTPPETKPREDVSMTSCEPFGKEGILIKIPAVISHRTESHVKPGRLTVLVSGLEIHDSSSLLMHRFEREDVDDIKVHSPYEISIRQRFIGKPDMAYRLISAKMPEVIPILEVQFSKKMELLEDALVLRSARTSSPAEKSCSVWHAASGLMGRTLHREPPAGDQEGTALHLQTSLPALSEADTQELTQILRRMKGLALEAESELERQDEALDGVAAAVDRATLTIDKHNRRMKRLT
What is the function of this protein?
Plays a role in intracellular membrane fusion.
What are the official names of this protein?
Synaptosomal-associated protein 47, SNAP-47, Epididymis luminal protein 170, Synaptosomal-associated 47 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the SVAP1 family.
What are the subcellular locations of this protein?
Endomembrane system. Cytoplasm, perinuclear region. Note=Appears to be exclusively membrane-bound.
Protein: PP190_ARATH
Sequence: MAFISRSKRYQSKARVYLSLPRSSNSSLFSLPRLFSTIEETQTPANANPETQSPDAKSETKKNLTSTETRPLRERFQRGKRQNHEKLEDTICRMMDNRAWTTRLQNSIRDLVPEWDHSLVYNVLHGAKKLEHALQFFRWTERSGLIRHDRDTHMKMIKMLGEVSKLNHARCILLDMPEKGVPWDEDMFVVLIESYGKAGIVQESVKIFQKMKDLGVERTIKSYNSLFKVILRRGRYMMAKRYFNKMVSEGVEPTRHTYNLMLWGFFLSLRLETALRFFEDMKTRGISPDDATFNTMINGFCRFKKMDEAEKLFVEMKGNKIGPSVVSYTTMIKGYLAVDRVDDGLRIFEEMRSSGIEPNATTYSTLLPGLCDAGKMVEAKNILKNMMAKHIAPKDNSIFLKLLVSQSKAGDMAAATEVLKAMATLNVPAEAGHYGVLIENQCKASAYNRAIKLLDTLIEKEIILRHQDTLEMEPSAYNPIIEYLCNNGQTAKAEVLFRQLMKRGVQDQDALNNLIRGHAKEGNPDSSYEILKIMSRRGVPRESNAYELLIKSYMSKGEPGDAKTALDSMVEDGHVPDSSLFRSVIESLFEDGRVQTASRVMMIMIDKNVGIEDNMDLIAKILEALLMRGHVEEALGRIDLLNQNGHTADLDSLLSVLSEKGKTIAALKLLDFGLERDLSLEFSSYDKVLDALLGAGKTLNAYSVLCKIMEKGSSTDWKSSDELIKSLNQEGNTKQADVLSRMIKKGQGIKKQNNVSL
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g37230.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: RS3_CALS8
Sequence: MGQKVHPKGFRLGIIKDWDSRWFANDKDFEKYLLEDYKIRRHIKEKLYNAGISRIEIERAAKRIKVIIHTAKPGIVIGRAGSGVEALRKELEKITGGKTISLDIKEIKVPELDAQLVAENIAAQLEKRVSFRKAMKQAMARALRSGAKGIKTMVSGRLGGADIARTEWYKEGRIPLQTLRADIDYGFAEAHTTYGRIGVKTWIYKGDVLPQKGAAAEKGGDK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RS13_ACET2
Sequence: MARIAGVDLPREKRVEIGLTYIFGIGRTLSNEILRKTGINPDTRVKDLTDEEISKLREVIDKEYKVEGDLRREIALNIKRLMEIGCYRGRRHRAGLPVRGQRTKTNARTRKGPKKTVGVQRKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SYP_SULIM
Sequence: MQITREKWSKNFSEWFDWVLREGEFYDYGRYPVKGMGVWMPYGFKLRQNIISIIRNLLDSTGHEEVLFPLLIPEDLLSRESTHIKGFEEEVFWVTKGGSEDLDVKLALRPTSEVAITTMENLWLKSYKQLPKKYYQIVSVFRYETKATRPMIRLREITTFKEAHTVHETYDDAQRQVEEAIEIYKKIFNNLAIPYVLSERPEWDRFAGALHTYAFDTIMPDGKVMQIGTVHHLGQNFSRALDFKIQKKDGSLDYPHQTSYGISDRAIASVIAIHGDDHGPILPPSVAPIKVVVVPIPAKNEEGTQQVMKYSVEICEMLNKNNITCVTDQDTEKTPGEKFYIWEIKGVPIRLEIGPRELASSTVFIKRRDNLKSYTVKKEEVVNKVKEVLNEIQEDLRKRAWESLKSRIEYANDIEKAKNLLENNSGIVEVPWCGSKECGLKIEELTNARVLGYPIEDRKVNDKCVICKMNAKTVLRVAKTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLDA_CLOSG
Sequence: MENNTNMFSGVKVIELANFIAAPAAGRFFADGGAEVIKIESPAGDPLRYTAPSEGRPLSQEENTTYDLENANKKAIVLNLKSEKGKKILHEMLAEADILLTNWRTKALVKQGLDYETLKEKYPKLVFAQITGYGEKGPDKDLPGFDYTAFFARGGVSGTLYEKGTVPPNVVPGLGDHQAGMFLAAGMAGALYKAKTTGQGDKVTVSLMHSAMYGLGIMIQAAQYKDHGLVYPINRNETPNPFIVSYKSKDDYFVQVCMPPYDVFYDRFMTALGREDLVGDERYNKIENLKDGRAKEVYSIIEQQMVTKTKDEWDNIFRDADIPFAIAQTWEDLLEDEQAWANDYLYKMKYPTGNERALVRLPVFFKEAGLPEYNQSPQIAENTVEVLKEMGYTEQEIEELEKDKDIMVRKEK
What is the function of this protein?
Component of the phenyllactate dehydratase complex FldABC that is involved in the fermentation of L-phenylalanine via a Stickland reaction.  This complex catalyzes the reversible syn-dehydration of (R)-phenyllactate to (E)-cinnamate in two steps, a CoA-transfer from cinnamoyl-CoA to phenyllactate, catalyzed by FldA, followed by the dehydration of phenyllactyl-CoA to cinnamoyl-CoA, catalyzed by FldB and FldC (PubMed:10849007, PubMed:11967068).  In vitro, FldA can use 3-phenylpropanoate as a better CoA-acceptor than phenyllactate (PubMed:10849007).
What are the official names of this protein?
Cinnamoyl-CoA:phenyllactate CoA-transferase, (E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase, (R)-phenyllactate CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: CFM1_GIBZE
Sequence: MKYSVAFVALAAVAAQAQSLADVPKCAIPCLDKAIASETSCDKTDLACVCKGFSAVRSKATSCVIDECGTDVAINEVLPATENLCKNPPKESEAKSTAEEEKPTTTAAATSTLVVVTTSAEVVETTAAATTTVAPIIPTTAAEEPATSTPAAATPTKGPEQANGAAGLKGLGALAMAAFAALAL
What is the function of this protein?
Suppresses host programmed cell death during infection by binding to Z. mays WAK17 isoform 2 and Z. mays LRR5, to prevent activation of Z. mays WAK17 isoform 1 and the downstream hypersensitive response.
What are the official names of this protein?
Effector CFEM1.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
Protein: TYOBP_MACMU
Sequence: MGGLEPCSRLLLLPLLLAVGGLRPVQAQAQSDCSCSTVSPGVLAGIVLGDLVLTVLIALAVYFLGRLVPRGRGAAEAATRKQRITETESPYQELQGQRSDVYSDLNTQRPYYK
What is the function of this protein?
Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity).  TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity).  Also has an inhibitory role in some cells (By similarity).  Non-covalently associates with activating receptors of the CD300 family to mediate cell activation (By similarity).  Also mediates cell activation through association with activating receptors of the CD200R family (By similarity).  Required for neutrophil activation mediated by integrin (By similarity).  Required for the activation of myeloid cells mediated by the CLEC5A/MDL1 receptor (By similarity).  Associates with natural killer (NK) cell receptors such as the KLRD1/KLRC2 heterodimer to mediate NK cell activation (By similarity).  Associates with TREM1 to mediate activation of neutrophils and monocytes (By similarity).  Associates with TREM2 on monocyte-derived dendritic cells to mediate up-regulation of chemokine receptor CCR7 and dendritic cell maturation and survival (By similarity).  Association with TREM2 mediates cytokine-induced formation of multinucleated giant cells which are formed by the fusion of macrophages (By similarity).  Stabilizes the TREM2 C-terminal fragment (TREM2-CTF) produced by TREM2 ectodomain shedding which suppresses the release of pro-inflammatory cytokines (By similarity).  In microglia, required with TREM2 for phagocytosis of apoptotic neurons (By similarity).  Required with ITGAM/CD11B in microglia to control production of microglial superoxide ions which promote the neuronal apoptosis that occurs during brain development (By similarity).  Promotes pro-inflammatory responses in microglia following nerve injury which accelerates degeneration of injured neurons (By similarity).  Positively regulates the expression of the IRAK3/IRAK-M kinase and IL10 production by liver dendritic cells and inhibits their T cell allosimulatory ability (By similarity).  Negatively regulates B cell proliferation (By similarity).  Required for CSF1-mediated osteoclast cytoskeletal organization (By similarity).  Positively regulates multinucleation during osteoclast development (By similarity).
What are the official names of this protein?
TYRO protein tyrosine kinase-binding protein, DNAX-activation protein 12.
What is the protein family that this protein belongs to?
Belongs to the TYROBP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS18_PHOPR
Sequence: MARFFRRRKFCRFTAEDVQEIDYKDVVTLKNYITEAGKIVPSRITGTRAKYQRQLARAIKRSRYLALLPYTDKHL
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RIR2H_RHOJR
Sequence: MSTLTPGRPYAPGRQGFSSLRAGGLNWDAFPLRLFTKGNAKFWNPTDLDFSRDAEDWEGLNSEQQRNSTYLVAQFIAGEEAVTEDIQPFMKAMAAEGRFGDEMYLTQFCFEEAKHTQVFRLWMDAVGLTRDLHPFVAENPYYRQLFYEELPGSLKVLETDPSPVNQVRASVTYNHVIEGSLALTGYYAWQKVCTTRGILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDSNWGVVQERMAELMPLALGMIDWVNKQFEVQPYGLDDQEFIAYAADRAQRRLGAIESARGRPVEEIDLDYSPEALEEKFGEEDAKAMSEAAG
What is the function of this protein?
Probable oxidase.
What are the official names of this protein?
R2-like ligand binding oxidase, Ribonucleotide reductase R2 subunit homolog, Ribonucleotide reductase small subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
Protein: Y6530_DICDI
Sequence: MKNLFKLNFLFIIFIFISIFAFPTNSQNTCPSGSLNSTAIPIKIIIASNSIAKNPPLSGMLAGSVCSSITGTITTFTFPNGPIINTVPSGLIGKPIIGKIVLDYLNAKYGLDFSTATISQSSSTVSISISNIVKH
What are the official names of this protein?
Putative uncharacterized protein DDB_G0280341.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.