PharMolix/UniProtQA huggingface dataset:
Protein: FTSW_THISK
Sequence: MSTGSLPLGLPSRDSLDGLRNSVDLPLLAAAALLLGLGLIMVASASMDLGERYYGNTWHFFQRQVLFAAIGLALATVMWAIPLERWERAGPWLLILVMVLLIAVLLPGVGRTVNGATRWIPIGMFNLQVAEPVKLLVVMYLAGYIVRHYSALRLHLRGFVRPLVVLGFGTVLLLLQPDFGGAAIMLAIGMGMLFLAGAKLWQFAALGATIAVGMAFVAVAAPYRVARLTAFLDPWQDPFATGFQLTQSLIAIGSGGWFGTGLGNSVQKLFYLPEAHNDFLFAVFAEEFGFIGVLALIALFAVVVWRCVKIGLWAERAGHAFGSHLAFGVAIWLALQSALNLAVNMGLLPTKGMTLPFLSYGGSSLIVTLMAIGLVMRVYREAQIPAPRQSTPPRRKRGQA
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: YBJL_SALCH
Sequence: MNINISDLLNGNYILLLFVVLALGLCLGKLRLGSVQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGIASPQLSSALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMITFQFSNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGINNGLGAVGGQMLIAGLVVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIVIIWPELG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYL_CAUVN
Sequence: MARYNPKDTEPKWREAWAKADVFKTGEINDGRPKYYVLEMFPYPSGRIHMGHVRNYAMGDVVARYKRAQGFNVLHPMGWDAFGMPAENAAMERGVHPKGWTYDNIAAMREQLKSLGISVDWSREFATCDPEYYGKQQAWFLRLLKRGLVYRKEASVNWDPVDMTVLANEQVIDGKGWRSGAVVEKRKLTQWFLRITDYADALIDGLKTLDRWPDKVRLMQENWIGRSKGLRFKFQFDGEAPDGMAEGLEVYTTRPDTLFGASFVGIAPEHPLAEQLAAANPQIQTFIADCRKGGTSEAEIESAEKLGYDTGLRVKHPLDPSITLPVWIANFILMDYGTGAIFACPAHDQRDLDFARKYDLPVLPVVLPNGEDPATFTVGKEAYVGPGKIFNSKFLDGLDVEAAKAEAIARIEAANQGQGATVYRLRDWGVSRQRYWGCPIPVIHCEACGVVPVPEDQLPVALPDDVTFDKPGNPLLRHPTWRHTTCPSCGGKAERETDTLDTFIDSSWYFARFADTQAAEPVGKDAADHWLPVDQYIGGVEHAILHLLYARFITRALKDEGLLSVEEPFAGLFTQGMVTHEAYKNEAGEWVEPSDVVITTEGSTRTAKHAKTGAPIIIGDIEKMSKSKKNVVAPEDIFEAYGVDSARLFVMSDSPPERDVQWTNSGVEGSWRFTHRLWNEFDSQPAGDFAHDDSDEAALALRKAAHKLIGFVTDSIEGFRFNSGVARLYEFLNALKAAPAEGASQAVLAARAEALNILARLVAPFTPHLAEEAWARMGGEGMVVDAPWPKADPALAADDERVLPIQINGKRRGEIKVKAGAPDDEVTKIALADPNVMAHLEGLTVRKVIVVKDRIVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUG52_SCHPO
Sequence: MHKISLQFFFVDNYFFFWKQSKYQSIYAIQIRCFFLTVNRTPIPKQTFSLIVFYILIMIIQHLKEIHYLISASAKLLLASNYLLELLISHNIQFSPIRSFFIIMV
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 52 protein.
Protein: TRUD_HELPY
Sequence: MNLNFMPLLHAYNHASIDFHFNSSARDFCVHEVPLYEFSNTGEHAVIQVRKSGLSTLEMLQIFSQILGVRIAELGYAGLKDKNALTTQFISLPKKYAPLLEKNTSNFQEKNLKILSLNYHHNKIKLGHLKGNRFFMRFKKMTPLNAQKTKQVLEQIAQFGMPNYFGSQRFGKFNDNHQEGLKILQNQTKFAHQKLNAFLISSYQSYLFNALLSKRLEISKIISAFSVKENLEFFKQKNLSVDSDTLKTLKNQAHPFKILEGDVMCHYPYGKFFDALELEKEGERFLKKEVAPTGLLDGKKALYAKNLSLEIEKEFQHNLLSSHAKTLGSRRFFWVFVENVTSQYVKEKAQFELGFYLPKGSYASALLKEIKHEKGENNDEF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RPC4_MOUSE
Sequence: MSEGNAAGEPSNPGGPRPLLSGGRGLIGRRPAPPLTPGRLPSIRSRDLTLGGVKKKTFTPNIISRKIKEEPKEEVTMKKEKRERDRDRQREGHGRGRGRPEVIQSHSIFEQGPAEMMKKKGNWDKTVDMSDMGPSHIINIKKEKRETDEETKQILRMLEKDDFIDDPGLKNDTRNMPVQLPLAHSGWLFKEESEEPEAKPFSAGPKEEDMEVDVPAVKVKEEPRDEEEEAKVKAPPRAARKTPGLPKDVSVAELLRELSLMKDEELLFLQLPDTLPGQPPTQDIKPVKTEVQGEDGQMVVIKQEKDREARLAENACTLADLTEGQVGKLLIRKSGKVQLLLGKVTLDVTMGTTCSFLQELVSVGLGDSRTGEMTVLGHVKHKLVCSPDFESLLDHKHR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.  Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.  Acts as nuclear and cytosolic DNA sensor involved in innate immune response.  Can sense non-self dsDNA that serves as template for transcription into dsRNA.  The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC4, RNA polymerase III subunit C4, DNA-directed RNA polymerase III subunit D.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPC4/POLR3D RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS13_RHOJR
Sequence: MARLAGVDLPREKRMEIALTYIYGIGRTRSKEILDATGVSPDLRSKDLSDEDLAKLREYIEESLKVEGDLRREVQADIRRKIEIGCYQGLRHRRGLPVRGQRTKTNARTRKGPKRTIAGKKKAK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: EFG1_TREDE
Sequence: MLDKMRNIGIMAHIDAGKTTTTERILFYTGKIHKIGEIDDGQATMDWMAQEQDRGITIQSAATTTYWKNFQINIIDTPGHVDFTAEVERSLRVLDGAVAVLCAVGGVQPQTETVWHQADRYKVPRICFVNKMDRIGADFFAVLKDVHEKFGVEVMPVQIPIGASDSFEGVIDLIAMKEIHWDAATEGEKYEYTAIAQERLALAEEWREKMLDTISSASDEITELILEGKDVPEELIKKEIRKAVLNQSYIPFLCGSARKNIGVQPLIDAVVDFLPAPNEVLPAEAFNPKKEEKLSVPCKAEGAPLGLVFKIQYDKDAGSLCYVRMYSGKIKSGDQVFNTGKKKRERVNRILRMHSNKSEQMDSVQAGDIAVFIGLKISQTGDTLGSEGQPLLLESMQFPEPVISVSVEPKSLSESDRLKEVLEILSKEDPTFTSREDSETGQLIISGMGELHIDVLTRRMLDDFKVEARVGNPQVTYRESITTEKTQTEKYSKQLGGKDNEAELTLTVRPLERGSGNRFVSKVKTFQKSGSGGTNALPEDLLEAVKRSIEGCFSSGIKVGYPCTDIEVELVSVKYNELTATPFAYEAAAAKCFDDACSAAAPVLLEPVMAVDIMSPKEFVGDAMSQITQRGGLISSMDSKASTDIVHAQAPMAKMFGFSTDLRSATQGRASFTMSFSHFEIKR
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP22_COLGM
Sequence: MAAQVPTEALKELNVGGPATNDKAANPTEGNGVDHDSDDSDEEGEEVAAPAAGGAAKKKKKNKKKKKKKSPTAQSDPPRVLMSSLFPNKNYPKGQEEEYRDENLYRTTNEEKRHLDNLNNDFLTDYREAAEIHRQVRQWAQKNIKPGQTLTEIAEGIEDGVRALTGHPGIEEGDAYKGGMGFPCGLSLNHCAAHYTPNAGNKMVLSQGDVMKVDFGVHVNGRIVDSAFTMAFEPQYDNLLAAVKDATNAGVKEAGIDVRVGDVGGVIQEVMESYEVEIDGTTYPVKSIRNLNGHTIERWSIHGTKSVPIVKSNDTTKMEEGDVFAVETFGSTGNGFVREDMEVSHYAKRGEGHAALRLDSAKRLLNVINKNFGTLPFCRRYLDRLGQDKYLLGLNNLVSSGIVEAYPPLCDKKGSYTAQFEHTILLRPTVKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-2, MAP 2-2, MetAP 2-2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF3_ORYNI
Sequence: MPRSRINGNFIDKTFSIVANILLRIIPTTSGEKRAFTYYRDGMLAQSEGNYAEALQNYYEATRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAILQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITKRFEFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RADA_METLZ
Sequence: MTALDIEEIPGVGPATADRLRDAGYITVESIATATPVDLAEAAELGESTTKKIIKAAREMADIGGFKTGTDILARRQDVLKLKTLVPEIDELFGGGLETQAITELYGEFGSGKSQIAHQLAVNCQLPQELGGLGGSCLYIDTENTFRPERIEQMAEGLELADLPEGYVVPTPDEFLANIHVARAHSSDHQMLLIDAARELSNELTASGLPVKLVIIDSLTSLFRSEYAGRGTLAGRQQKLNRHMHDLFKLVDDLNAVALVTNQVMANPGLLFGDPTKPIGGNIVGHTATYRVYLRKSKAGKRIARLVDSPNLPEGEATFMVETAGIKPC
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: A85A_MYCUL
Sequence: MKLVDRFRGAATGTSRRLMVGAVGAALLSGLVGFVGGSATASAFSRPGLPVEYLQVPSVAMGRNIKVQFQSGGANSPALYLLDGMRAQDDFSGWDINTPAFEWYYQSGISVAMPVGGQSSFYSDWYNPACGKAGCTTYKWETFLTSELPQYLSANKGVKPTGSGVVGLSMAGSSALILAAYHPDQFVYSGSLSALLDPSQGIGPSLIGLAMGDAGGYKASDMWGPKDDPAWARNDPMLQVGKLVANNTRIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSNMKFQAAYNAAGGHNAVWNFDDNGTHSWEYWGAQLNAMRPDLQHTLGATPNTGDTQGA
What is the function of this protein?
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M. tuberculosis to murine alveolar macrophages (AMs).  They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor).  They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM.  FbpA mediates triacylglycerol (TAG) formation with long-chain acyl-CoA as the acyl donor and 1,2-dipalmitoyl-sn-glycerol (1,2-dipalmitin) as the acyl acceptor.  It has a preference for C26:0-CoA over C18:1-CoA (By similarity).
What are the official names of this protein?
Diacylglycerol acyltransferase/mycolyltransferase Ag85A, DGAT, Acyl-CoA:diacylglycerol acyltransferase, Antigen 85 complex A, 85A, Ag85A, Fibronectin-binding protein A, Fbps A.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial A85 antigen family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cytoplasm.
Protein: C102A_XENLA
Sequence: MSQSSDPSPRLVESPLLLQSSDLFCNLDIPQLERIRHPDSLTPSPNSVPPSPMLPIPVSVPNGDWESREELRLRELEEARARAAQMEKTMRWWSDCTANWREKWSKVRAERNKAREEGAQLRSRLEILSKELGALKRERQEAATETEQLRKELERLQGKARVLVSNDHDIEEPVRDVEIEKLTKNKDSDLDNSVRLECWEIQNGGPSRSPRPRNWEDVSPSEDDTTKITALKLRLDESQKVLLKEREDKMLLNKTIEKMEAEISQWKMKCEELNKSRQEAVKQLTLLRERHQDELGRISEDLQDELGVRSSMDKKLAELRAEMEGLQAENAEEWGRRERLETEKLNLERENKKLRLQIQDLEEILTRKRRQSASALDTDLKSIQAELFEKNKELSDLRHSHSKLKKQYHERSSEFSHANRRVEQLESEVKKLRLRVEELKKELGQAEDELDEAQNQIRKLQRTLDEQTELNENLQVQLEHVQSRLRRQQNPPLFGKLRASRFSNDDAVDLGSDPDEDDLQIQVP
What are the official names of this protein?
Coiled-coil domain-containing protein 102A.
Protein: MURC_ECODH
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEFPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYDDFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPARVAEMLAPVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYNC_BRUMA
Sequence: MTVYICPETGDDGNDGSELKPLRTLYQAMIITKSSKGDFLIRTKKDGKQIWEAASKTALKKSWKHYEQEMLKNEKVAAKMLEKDATEVGVKAALEEAKKVQIELDTSLSYITGVKIRDLVKHRNERVCIKGWIHRMRRQGKSLMFFILRDGTGFLQVLLMDKLCQTYDALTVNTECTVEIYGAIKEVPEGKEAPNGHELIADFWKIIGNAPPGGIDNVLNEEASVDKMLDNRHLVIRGENAAALLRLRAAATRAMREHFYNAGYLEVAPPTLVQTQVEGGSTLFNLDYFGEQSFLTQSSQLYLETCIPTLGDVFLHCSVLQGGKISHSSTLAEYAHVEAECPFITLDDLMEKIEELVCDTVDRLLADEEAKKLLEHINPKFQPPERPFLRMEYKDAIKWLQEHNVENEFGNTFTYGEDIAEAAERFMTDTINKPILLNRFPSEIKAFYMQRDAQDNTLTESVDLLMPGVGEIVGGSMRIWKFDELSKAFKNVEIDPKPYYWYLDQRLYGTCPHGGYGLGLERFICWLTNTNHIRDVCLYPRFVGRCVP
What is the function of this protein?
Potentially protective antigen in lymphatic filariasis.
What are the official names of this protein?
Asparagine--tRNA ligase, cytoplasmic, Asparaginyl-tRNA synthetase, AsnRS, Potentially protective 63 kDa antigen.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_COLP3
Sequence: MRHYEIVFMVHPDQSEQVSGMIQRYTDLINAAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNIEAPQVVIDELETAFRYNDVVIRNMIMRTKDAVTEASPMAAAKEERRDDRREVKKDVAAAPVEAKEDSVEEKSEEAASEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ENKUR_PIG
Sequence: MDPTYSSESIYNLIPSDWKEPPQPPRYISIFKATVKDDMQKFKTAMKTMGPAKLEVPSPKDFLKKHSKEKTLPPKKKFDRHEPKKPPVPLRTEHPVMGIQSEKNFINTNAANVIMGVAKKPKPVYVDKRTGDKHDLETSGLVPKYINKKDYGVTPEYICKRNEEVKKAQEEYDNYIQENLRKAAMKRLSDEEREAVLQGLKKNWEEVHKEFQSLSVFIDSIPKKMRKQKLEEEMKQLEHDIAVLEKHKIIYIANKK
What is the function of this protein?
Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel (By similarity).  Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity).
What are the official names of this protein?
Enkurin.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Note=Sperm acrosomal crescent and flagellar principal piece.
Protein: CITD_TREDE
Sequence: MQIKREAVCGTLQSNDCLVRIVPSEKLELDLKSSVLNEFGAQIKKTVQEVLDEFEVKNAKLFIEDKGALDCTIKARVETALRRANEK
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_CHESB
Sequence: MPEARRTTIDAGEVERFSALAQEWWNPNGKFRPLHKFNPVRLAYIRDNVAAHFGRDPRAAKPFEGLRILDIGCGGGLLCEPMARLGASVVGADASATNIEVARLHALESGVSIDYRAETAEALADQGEKFDIILNMEVVEHVADIDLFIEKCAEMLKPGGLMFVATINRTLKALGLAIIGAEYVLRWLPRGTHQYGKLVRPDELERALASAGLITKDRTGVVYNPLTDRWNRSRDMDVNYMVLAEKPTAEAMI
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: GLPO_LACLA
Sequence: MAFSKKTRQEAITKIQNEEMDLLVIGGGITGAGLTLQAAAAGMKVAVLEMQDFSEGTSSRSTKLVHGGIRYLKNFDVEVVSDTVSERAVVQGIAPHIPKPDPMLLPIYDDEGKTTFDMFSVKIAMDLYDRLAGVDEDSPYANYTISPEEVLRREPLIKKKGLQGAGVYLDYRNNDARLVIDNIKKAVEDGAQAISKMKVIDFIYTDGQISGIRARDLLTDQVIEVKAKLVINTSGPWVDKIRYLNFTRPIVPKMRPTKGVHLVVDAAKLPVPQPTYFDTGKHDKRMVFAIPRENKTYFGTTDTDYHGDFTDPKVTQEDVDYLLDVINFRYPEANITINDIEASWAGLRPLLGGNSGSDYNGGDNGAVSETSFNAVVEAVLRYKNKTATKAEVEHLLNNMESSLSEKGDAPSSVSRGSSLERESDGLITLAGGKITDYRKMAAGAMELICQLLEEDFGLKYEPIDSKKYQISGGEFDPTKVEEVVAENMKVGVAAGLTEEEAKYIADFYGMNALQVFAYASEMEAYEGLSLAESARLCYALEDEMILTPVDYLLRRTNHILFMREGVDAIKVHVVNAMADDLGWSAEEKAEQEKALEEALRESDLSDLKK
What are the official names of this protein?
Alpha-glycerophosphate oxidase, Glycerol-3-phosphate oxidase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRPSA_DICDI
Sequence: MGDRIKILTGNAHRELASEISDDLNLALGKAHVGKFSNGETSVMISESIRDMDVYIIQPTCNPNVNDNLMELLIMADAIRRASAHRITAVIPCFGYARQDKKDKSRAPITGKLVANLIETAGIDRVITMDLHASQIQGFFNIPVDNLYAEPQIIKYIRKYIPGEKVIVSPDAGGVKRAKSISDKLDADLAIIHKERKKANEVSGMILVGDVKDKVALIVDDMADTCGTLVSACEMLISKGATKVYALVTHGVLSGDAIQKLNESSLTELVITNTIPHAEKAAKCPKIKTINIAHTLSEAIRRTHHGESISSLFSDTK
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase A, Phosphoribosyl pyrophosphate synthase A.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
Protein: KDSB_AERS4
Sequence: MSFVVVIPARYASTRLPGKPLADIHGKPMVQHVVEKALQSGADRVIVATDDERVHSALASFAEQAGVEVCMTSQDHQSGTERLAEVCRHYGFSADTIVVNVQGDEPLIPPAIIRQVADNLAAASAPMATLSVPIQDAEEAFNPNAVKVVTDKEGYALYFSRACIPWDRDRFAASDRAAGSHEQIGDHYQRHIGIYAYRAGFIQRYVDWAPSVLEQVEALEQLRVLWYGEKIHVAQALQAPPVGVDTQADLDKVRALLAN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AA1R_HUMAN
Sequence: MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
What is the function of this protein?
Receptor for adenosine.  The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
What are the official names of this protein?
Adenosine receptor A1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_ESCF3
Sequence: MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKNAIRRIEEITAEIEVGRVYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRIRLSIKEATEQSQPAAAPEAPAAEQGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_PROM2
Sequence: MTNFKLKIASRRSKLAMVQTLWVKDQLERNIPNLDVSIEAMATQGDKILDVALAKIGDKGLFTKELEAQMLVGHADIAVHSLKDLPTNLPNGLKLGCITKREDPADALVVSKKNDYYKLETLPEGSIVGTSSLRRLAQLRNKYPHLVFKDIRGNVITRIEKLDAGEFDCIILAAAGLKRLGFESRIHQIIPSEISLHAVGQGALGIECKSDDKKVLEIINVLEDKPTSQRCLAERAFLRELEGGCQVPIGVNSNIDNGQLYLTGMVASLDGKKLIKDQVIGNINNPELVGIELAKRLKLQGADKILSEIFEEFRENKN
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: MURA_PROMM
Sequence: MPAAVSISQEILKPHLEIQGGHTLSRELKVSGAKNSALVLMTSALLSEGPLELHNVPQLTDIQGMADILASLGVRVKRSQETVWLQADGLHHAEPPYDLVNGLRASFFCIGPLLGRLGHAKVPLPGGCRIGARPVVEHIRGLKALGAMVKVEHGVVTASVPGTSRRLKGAAIVLDCPSVGATETILMAAVLAEGTSTIENAAQEPEVQDLAKMLNAMGARVSGAGGPIITIEGVERLHGCNYSVIPDRIEAGTFLIAAAITRSIVRVSPVIPEHLNAVLQKLRDCGCTLEIDKQGITLIPGDLHGVDIITQPFPGFPTDLQAPFMALLTTAKGTSVVTEKIYENRMQHVAELQRMGASIRLQGNTAVVEGIPQLSAAPVSGNDLRAAAALVLAGLAAHGISQVDGLNHLDRGYDEIETKLNASGAHILRHQPSG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_ECO24
Sequence: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.