PharMolix/UniProtQA huggingface dataset:
Protein: CSPLS_ARATH
Sequence: MVKLRETEVILRLCIVFFLLLTSCLIGLDSQTKEIAYIHKNVSFRYLLALEAELYIDVVVAAYNLVQLGLGWYNVEQKTSNPKWFSYLLDQTAAYVVFAGTSAAAQHSLLVVTGSRELQWMKWCYKFTRFCFQMGSAIILNYIAAALMVLLSSISAFNLFRLYSPKRFFRFKSSS
What are the official names of this protein?
CASP-like protein 2C1, AtCASPL2C1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSH3_ASPOR
Sequence: MPLSSQPSSSNLKRKQPTISSFFTKKPQLSQESISNDVLEKEERDEEREEVAKQEEGLRENGGTRSNNVDDDEDDVVAPASKRARTNGSHSQNTIETPKEKHVERPLPSDSIQKTELSKFASSPATEGETKERTKERERLHQKFVRRLGGPDCLIGIGRNTAPEAVPEEVGEGDEDDEPSPPPAAKGKATAKKGARKLTPMEKQVIDIKRKHMDTVLVVEVGYKFRFFGEDARTAAKELNIVCIPGKFRFDEHPSEAHLDRFASASIPVHRLHVHVKRLVSAGHKVGVVRQMETAALKAAGDNRNAPFGRKLTNLYTKGTYIDDMEGLEGSTASMSATGTSMATGYMLCITETNTKGWGNDEKVLVGIVAVQPATGDIVYDEFEDGFMRSEIETRLLHLAPCEVLIVGDLSKATEKLVQHLSGNKTNAFGDEIRVERAPKAKTAAAESHSHVSSFYAERMKKVNATNDVQASSLLQKVLNLSEQATICLSSMIKHMSEYGLEHVFQLTKYFQHFSSRSHMLLNANTLNSLEIYHNQTDHSTKGSLFWTLDRTQTRFGQRMLRKWVGRPLLNKLGLEERVDAVEELKNLERVALVEQMKCLLGRIKTDLEKSLIRVYYGKCTRPELLTLLQTLQMIAQEFAGVQSPADTGFSSPLISKAVASLPTILEDVVRFLDKINMHAAKNDDKYEFFRESEETDEITEHKLGIGAVEHDLEEHRSTAGEILGKRKVDYVTVAGIEYLIAVENKSPSIKKVPASWVKISGTKAVSRFHTPEVIRLLRQRDQHKEALAAGCDKAYATFLAEISASYQSFRDSVQSLATLDCLISLATIANQPGYVKPEYTNHTCIQVDQGRHPMVEQLLLDSYVPNDIDLDSDKTRALLVTGPNMGGKSSYVRQVALIAIMGQIGSYVPARSAKLGMLDAVFTRMGAFDNMLAGESTFMVELSETADILKQATPRSLVILDELGRGTSTHDGVAIAQAVLDYMIRSIRSLTLFITHYQHLSSMVHSFPDHELRNVHMRFTESGPTEEEITFLYEVREGVAHRSYGLNVARLANLPAPLIELAKQKSAELEQKIHRRRLAGLVRTVGDILADSAKADESLIERLISSAEQL
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair.  Msh3 provides substrate-binding and substrate specificity to the complex.  When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs.  Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication.  After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
What are the official names of this protein?
DNA mismatch repair protein msh3, MutS protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS10B_ORYSJ
Sequence: MIIPKKNRNEICKYLFQEGVLYAKKDYNLAKHPQIDVPNLQVIKLMQSFKSKEYVRETFSWQYYYWYLTNDGIEHLRNYLNLPSEIVPATLKKSARPPGRPFGSGPPGDRPRGPPRFEGDRPRFGDRDGYRGGPRGAPGDFGGEKGGAPAEFQPSFRSSGGRPGFGRGGGGGFGAGPTSSSME
What are the official names of this protein?
40S ribosomal protein S10-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_DESHY
Sequence: MEIKWLHLKSFRNYQDQEVDFRPGLTILQGENGQGKTNILEGIYYLLTGKSYRVHREQELARWGENEFHLYGDFIVQRRKLRLESHYQDKRKIIKINQIPCRKLSEYVGTINVVFFSPDDLVMVKGGPAERRRFLDLHIAQHHSKHIQLLNAYNKVLQQKNALLKQGQGGSKSQIAQIELWNEQILRIGSEIIRNRWEFTGLLSRKGQEIYGQISSGKEELTMDYHALGKNNLEEALAAFPKLLAEKMSLEMERKMVLIGPHRDDILFKLNERSARLYGSQGQQRSIVLSTKLAELEVIRQEKGDYPLLLLDDVLSELDRFRRDYLLDYTKSLQQTIMTMTSAETLTQRASLLLKVEKGQIGRIE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN296_MOUSE
Sequence: MSRRKAGRVPRRVDPDTDTDIEMPDLVMDVKPDLDLRSLAQGPWIARDMPISDVKRQLQTASRPLGAPSTCAPRMPLSSKSSDRQPWTDKHPDLLTCGRCGKIFPLGAIIAFMDHKKQGCQLLQVSDPISESKELKALSCLQCGRQYTSPWKLLCHAQWDHGLCIYQTQHLDTPEAPLLGLAEVAAAMSAVAVVAPVESKPPPVSSAARRSPTCDVCKKTLSSFSNLKVHMRSHTGERPYSCDQCSYACAQSSKLNRHKKTHRQLAPGSPSTSASSRGVSPAAPPEPAAYAAAPASTLPSQTVEKAGAAATAGVQEPGAPGSGAQGGPGFVGWGAPAKVERTDPVKIEKTAPRKSHGPGGKCEFCGKSFTNSSNLTVHRRSHTGERPYTCDQCPYACAQSSKLNRHRRTHGLGTGKTVKCPHCLVPFGLQATLDKHLRQKHPEMA
What is the function of this protein?
May be a transcriptional corepressor with KLF4.
What are the official names of this protein?
Zinc finger protein 296, Hepatocellular carcinoma-associated antigen MHCA108.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AAC2_MYCS2
Sequence: MLTQHVSEARTRGAIHTARLIHTSDLDQETRDGARRMVIEAFRDPSGDSDFTDDFTDDDWDHALGGMHALISHHGALIAHGAVVQRRLMYRGPDGRGHALRCGYVEAVAVREDRRGDGLGTAVLDALEQVIRGAYQIGALSASDIARPMYIARGWLSWEGPTSVLTPTEGIVRTPEDDRSLFVLPVDLPDGLELDTAREITCDWRSGDPW
What is the function of this protein?
Catalyzes the coenzyme A-dependent acetylation of the 2' hydroxyl or amino group of a broad spectrum of aminoglycosides.  It confers resistance to aminoglycosides.
What are the official names of this protein?
Aminoglycoside 2'-N-acetyltransferase, AAC(2')-Id.
What is the protein family that this protein belongs to?
Belongs to the AAC(2')-I acetyltransferase family.
Protein: RS3_HYDCU
Sequence: MGQKVHPIGIRLGITKDWNARWYADSKNYSDFLISDIEIRKELNEKLKHASVSQINIERVANGVRVTIHTARPGVVIGKKGEDIEKLKQALIAKTGMPVNINIEEIKKPELDAKLVAEGIAQQLEKRIQFRRAMKRAVSNAMRLGAQGIKVNVSGRLNGAEIARAEWYREGRVPLHTLRADIDYATFEADTTYGKIGVKVWIFKGEKLEKISMVSDDKKQSKGKKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ASTB_PSEPK
Sequence: MKSYEVNFDGLVGPTHNYGGLSYGNVASQSNSQQASNPREAARQGLAKMKALADMGFKQGVLAPQERPDVAALRRLGFSGSDAEVIQRAAREAMPLLVASCSASSMWVANAATVSPSADTADGRVHFTAANLNCKYHRSIEHPTTSRVLGAMFNDEKYFAHHAALPAVAQFGDEGAANHTRFCRAYGEAGVEFFVYGRSAFDSRYPAPQKYPARQTLEASQAVARLHGLSDDGVVYAQQNPAVIDQGVFHNDVISVGNGEVLFYHEDAFLETDAVLGQLRAKLASKGGNFQAICVPRAAVAVEDAVRSYLFNSQLLSREDGSMLLVVPEECRNNERVWAYLGQLTSQGGPVKEVKVFDLKQSMQNGGGPACLRLRVALKEAELAAVNQGVIMTATLYDTLLQWVDRHYRDRLGEADLADPQLLVECRTALDELTQILKLGSVYPFQRQP
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: P2RY1_MOUSE
Sequence: MTEVPWSVVPNGTDAAFLAGLGSLWGNSTVASTAAVSSSFQCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAIYVSVLVWLIVVVAISPILFYSGTGTRKNKTVTCYDTTSNDYLRSYFIYSMCTTVAMFCIPLVLILGCYGLIVKALIYNDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPEMCDFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEEMTLNILSEFKQNGDTSL
What is the function of this protein?
Receptor for extracellular adenine nucleotides such as ADP.  In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation.
What are the official names of this protein?
P2Y purinoceptor 1, P2Y1, ADP receptor, Purinergic receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DB110_HUMAN
Sequence: MKIQLFFFILHFWVTILPAKKKYPEYGSLDLRRECRIGNGQCKNQCHENEIRIAYCIRPGTHCCLQQ
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 110, Beta-defensin 10, DEFB-10, Beta-defensin 11, DEFB-11, Beta-defensin 111, Defensin, beta 110, Defensin, beta 111.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NADK_ALKCK
Sequence: MKFTVASRGDTLSDELCDTIKTRLLAADLAHDSDKPDIVITVGGDGTFLEAFHSYAHRLEETAFVGIHTGHLGFYADWVPEETEHLITHIIKTPFQIVEYPLLEVVIRYRGGQREPRRHLALNESTIKSTEGSLVCTVEIKGEAFETFRGDGLCMSTPSGSTAYNKALGGAILHPSLASIQLSEMASINNRIYRTLGSPLVLPQHHTCLLKLLNDVSVQVTIDHFNVPVFAENVDTIQVRVAEEKVRFARFRPFPFWKRVKEAFISE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3839_CLOBJ
Sequence: MRFVIVTGLSGAGKTQAIRSLEDLGFFCVDNLPPTLIPKFAEACYQTEGKIKKIALVIDIRGGKFFDDLFESLKYLKEEGYKYEILFLDASDEVLIKRFKESRRKHPLSPDGRILNGISMERNRLREVKDRADNIINTSELATRELREAINEIYGEHDQIENQLIITVLSFGFKHGIPLDSDLVFDVRFLPNPYYIKELKQYSGKDKKVSDYVMSFDVTNKFVNRLEDMLDFLIPNYFKEGKRQLIISIGCTGGRHRSVAIANAIYEGLKSKGHKVNIDHRDINEDIHKGGKKL
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein CLM_3839.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: ANMK_ECODH
Sequence: MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGQLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: YOPT_BACSU
Sequence: MAGYLNNIALNLEIVLKNKADSPEVSETLVTRICENLLLSKEVSFLKADGSVENFKLSDMEYEITNTEELPE
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YopT.
Protein: C4D20_DROME
Sequence: MWLTLITGALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFDKYGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELKPMLNFILRSASGINVGLRPRKALR
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Probable cytochrome P450 4d20, CYPIVD20.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: NAGA_BOVIN
Sequence: MRGGQGAARAPVIQFTNCRILRGGALLREDLWVRGGRILDPEKLFFEERRVADEQRDCGGCILAPGFIDVQINGGFGVDFSQASEDVGSGVALVARRILSHGVTSFCPTLVTSPLEVYHKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAHLRSFEADAFQDVLATYGGLDNVRIVTLAPELGHSQEVIRALTALGICVSLGHSVADLGTAEEAVQSGATFITHLFNAMLPFHHRDPGIVGLLTSDRLPAGRHIFYGMIADGIHTNPAALRIAHRAHPKGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLTAYVAGTNTLSGSIAPMDTCVRHFLQATGCSVESALEAASLHPAQLLGLEKRKGTLDFGADADFVVLDDSLHVRATYISGELVWQVEEARP
What is the function of this protein?
Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.
What are the official names of this protein?
N-acetylglucosamine-6-phosphate deacetylase, GlcNAc 6-P deacetylase, Amidohydrolase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. NagA family.
Protein: G3P_BUCBP
Sequence: MTIKIGINGFGRIGRVLFRLAQLRSNIEILAINDLINVQYIAYMLKYDSIHGNFNGKIVIKNETLFVNGKKIRITNEKDPKNLMWGDLNIDVVIESTGIFLTTEDSYKHIQAGAKKVIITSPPKDNTPMFVRGVNFNEYVGQKIVSNASCTTNCLAPLAKVINDEFEIVEGLMTTVHATTATQKTVDGVSYKDWRGGRSALQNIIPSTTGAARAVGKVLPELNGKLTGIAFRIPTANVSVVDLTVRNKKIATYEDICQIIKYASNHDMKEVIGYTEDHVVSSDFNGNTLTSIFDAKAGLSLNNNFIKLVSWYDNECGYSSKVLDLSEFISTFS
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_YERPS
Sequence: MERCVFYISDGTAITAEVLGHAVLSQFPINVTTFTLPFVENAARAQSVCKQINEIYQDTGVRPLVFYSIISLEVREIIQRSEGFCQDIVQALVAPLQGELGVPPQPVLNRTHGLTESNLDKYDARIAAIDYALAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLQLPAALKPFQHKLFGLTINPERLAAIREERRENSRYASLRQCRMEVGEVEALFRKNQIRYLNSTNYSVEEISTKILDILGMSRRMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: FLIE_PSEFS
Sequence: MSQGIEFNRLMLDMRSMQMDAMAQPKSVAPAPELGQSSFADMLGQAINKVSDTQQASSQLANAFEIGKSGVDLTDVMVASQKASVSFQALTQVRNKLVQAYQDIMQMPV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: LGT_STUS1
Sequence: MLPYPQIDPVAIAIGPLQIHWYGLMYLIGIGGAWWLASLRVQRFAPEWPKDKLSDLVFWVAMGVIVGGRLGYVLFYDLAAYINQPSLILQVWKGGMSFHGGLIGVLLCSWIFARRNGKSFFELMDFIAPFVPIGLGAGRIGNFINAELWGKATDVPWAMVFPTDPQQLARHPSQLYQFALEGVALFVILWLYSRKPRPTMAVSGLFAVCYGIFRFIVEFVRVPDAQLGYLAFGWLTMGQVLCIPMVLLGAGMIAWGYRREAGRAPA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
Protein: GYRB_RHOCA
Sequence: EFVKYLDRSKTAVMPDPIYMVGEVRGIGVEVAMWWNDSYHETVLPFTNNIPQRDGGTHLAGFRGALTRTITKYAQDSGIAKREKIDFTGDDAREGLTCVLSVKVPDPKFSSQTKDKLVSSEVRPAVENLVNEKL
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPSA_BACSU
Sequence: MKVLAITGYKPFELGIFKQDDKALYYIKKAIKNRLIAFLDEGLEWILISGQLGVELWAAEAAYDLQEEYPDLKVAVITPFYEQEKNWKEPNKEQYEAVLAQADYEASLTHRPYESPLQFKQKNQFFIDKSDGLLLLYDPEKEGSPKYMLGTAEKRREQDGYPIYFITMDDLRVTVEEDSY
What are the official names of this protein?
UPF0398 protein YpsA.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: PMIP2_CRYNB
Sequence: MRRLQQSLRRRSARRCPFILIPHRLLTTSYASYKPAPQATLEIEDTNSPTFLLKTSPIQLPARATSDDSAIKAHFDLPHSIFGDMVGVRREHVKGLFHYDSLTQPESLMRLTDRTLIQASAIVQRIVVAPQDPTGRELRLVVKNLDRLSDILCGVIDMCELIRNVHPHQDWVNQSDRTHQILCSFMNELNATRGLYESLAKAIAHPFNDPLTTSELRVARIFLTDFERSGIHLPPSVRERFVKHSDALLFLGRSFLSSASSGPSTVPHIEIPDPHRLLTGLGRQFVDSLPRTGRNGQAVIEPGSWEAQMILRYAREGRARELVYVGGMRADKKRISVLEAMLKERAELASVLGKNNWAEVVLVDKMTKTPENVMRFLTSLAQHHQPVARAEVDMLRRMKATALTGNYFDPRNSRTRHLPLFHAWDRDYYSDKYLTSLIPTGSPPSISPYLSTGTVMSGLSRIFSRLYGISFKPAVVSPGEVWHPSVRRLDVVHEEEGLIGVIYCDFFSRIGKSSGAAHYTVRCSRRVDDDDIDGDGLPEDWDKPYGPGLEADKESLSGKPGKYQLPIIALSMDVGTVNEGRPALLNWQELETLFHEMGHAIHSMIGRTEYHNVSGTRCATDFVELPSILMEHFVSSPEVLSTLAFHHATGEPLPIPVIEAHLALNQSLSALETHGQIAMALLDQKYHTLRHGQDSFDSTAIWFQLQQEIGVIQPVPGTAWQMQFGHLYGYGATYYSYLFDRAIAGKIWSTLFHRSGTSQAYDRKAEGILSREGGELLKEKVLKWGGGRDPWEMVGDVIGGVEGDELSKGDERALALVGSWSVV
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase 2, MIP 2, Octapeptidyl aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL24_NOSP7
Sequence: MATKQGTPKVFHKMHVKTGDTVQVIAGKDKGKIGEIVQALPQLSKVIVKGVNIKTKHVKPQQEGESGRIVTQEFPIHSSNVMLYSTKQNVASRVCYTFTSEGKKVRKLKKTGEILDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MOAC_SHIBS
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: ARAB_SHIFL
Sequence: MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKAQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDTPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: SLX12_TRYCC
Sequence: MDTRFHCVYLLTSLDPQCAGEYYIGYTVDPIRRLRQHNGEIVSGAWRTKRRGRPWELLCCVSGFGEDRIALKFEWCWQHPTKSTRLKTQMTQLRGVHRLPYAVGVLHLLLRADLFARLQLTLHIFEPEHVGRVVAELQGRVPSIPPLVATSLLRIEEITKERFMSLYLDGVSGGDGTAGDGCVYFVTAPLSSQPEADAPSRRVRSCRYLSEEDIFRQHARVKELLEANQCPCALCSLPLRSPYFVRCSRTPFCTLRAHLACLAMWFTYETMQKRDATMGQSTRNERSGEYSNKIKDDSNDGTMDAHASGRQLHSLSVNNADFSSSRDAGSILDSSGHISAFEESRCASSPSLTLLPSQPCPCPLCDEPLQWGALVHDLKRRAVLEKRWMERQRREKIEAALAERLQRLQNSSLTERKSRRKAKPALGQKRNRGEYCGDTVGDGGKEAITNWRARVMDGCDSWNDTNDFSHSVSLPPSGDEGYACDSSRRGVGGSKHTTRMTDEGKNDSITDICDCVLQLTEFNLDEWLDA
What is the function of this protein?
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COCH_MOUSE
Sequence: MPSSRIPALCLGAWLLLLLLPRFARAEGAVPIPVTCFTRGLDIRKEKADVLCPGGCSLEEFSVFGNIVYASVSSICGAAVHRGVIGTSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSASFAVTKGKSSTQEATGRAVSTAHPPSGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTADTGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVAFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYNTKENVLAVLANIRYMSGGTATGDAIAFTVRNVFGPIRDSPNKNFLVIVTDGQSYDDVRGPAAAAHDAGITIFSVGVAWAPLDDLRDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLESQQ
What is the function of this protein?
Plays a role in the control of cell shape and motility in the trabecular meshwork.
What are the official names of this protein?
Cochlin, COCH-5B2.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: LPXB_SHESA
Sequence: MSKKSQLVFAMVAGELSGDILGAGLMAALQKTHPNARFVGIGGPRMEALGFESLFAMEELAVMGIVEVLSRLPRLLHVRSSLIKSITELKPDCFIGIDAPDFNIGLELKLKAQGIKTVHYVSPSVWAWRPKRIFKIAKATNMVLSLLPFEKAFYDKHQVPCTFVGHTLADDIPLESDKASARQLLELDPEAEYLAILPGSRGGELKQLAEPFVKAALLIKQQFPDIRFVTPLVNQKRREQFEQALKAHAPDLEIHMVEGKSREVMAAADGILLASGTATLEAMLIKRPMVVAYRVSPLTYQIAKTMMQVNRFSLPNLLAGRDVVPELIQHDCTPEKIAEAVGVELNRDFTPIKAEFERLHQMLRCDASQKAAEAVLALVDAKDVN
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.