PharMolix/UniProtQA huggingface dataset:
Protein: RSMH_CHLCV
Sequence: MAETPFHIPVLVNECLSWFSDRNPRSFCDVTVGAGGHAEAFLSTYPSIISYDGSDRDATALSLARERLEKFGDRVHLHHASFEDLAQDPKENVYDGILADLGVSSMQLDTLSRGFSFQGEDHDLDMRMDTSQGITASEVLNTLREEELGKIFREYGEEPHWKNVANAIVHFRRRKKIITVKDLKEATARVFPSYRLRKKIHPLTLIFQALRVYVNQEDVQLKVLLESAMRWLAPKGRLVIISFCSSEDRPVKWFFREAEKSGLGKILTKKVVMPTYEEIRRNPRCRSAKLRCFEKTS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2181_PSEA7
Sequence: MDPKLLDILACPLTKGPLVLSEDKSELISKQAGLAYPIRDGIPVMLESEARALNVDERLDK
What are the official names of this protein?
UPF0434 protein PSPA7_2181.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: Y1965_MYCSJ
Sequence: MPSVSVWVRSLAPMTTWTRAAIGALGEDLAVKHLDSLGMRVLERNWRCRYGELDVIAEDPAARAVVFVEVKTRTTDHFGGVVQAVTPQKVRRLRRLAGLWLAGRDERWAAVRIDVIGVRIGRQATPEITHLTGVA
What are the official names of this protein?
UPF0102 protein Mjls_1965.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: TRPC_CHLT3
Sequence: MTYLDKILEHKRKEIEALKPQNFKKQFESQAENLPAPRDFAAALRRKAPSEPLRLIAELKKASPSRGVMVHDFKPLEIAERYRTLGASAYSVLTDEEFFQGHANYLKAVRENFDLPVLRKDFIIDESQIYEARLLGADALLLIVAALSPEALLQFRELAESLGMSALVEVHSKPELDIAVACGATIIGVNNRDLRTFKVNIQTSVELFASYPNDVIAVSESGIKTPEDLQQLADAGFDAVLIGEGLITSERLAAYGWNEK
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: DISA_CLOK5
Sequence: MRLEKEKELKSILKLLAPGTQLREGLENILRAKTGGLIVLGDSEQILKVVDGGFAINSEYSPSYIYELAKMDGAIILSSDLKKILYANTQLIPDSTIPTFETGTRHRTADRVAKQTGVIVIAISQRRNVITVYRGHIKYVLRDSSVMLGRANQALQTLEKYVAVLDRVVNNLNILEFQDIVTLFDVMTAIQRTEMVMRIVSEIEIYICELGNEGRLISMQLNELIKSVERDGIFMIRDYCQTDMDYDEIYRQIQEISSDDVLNLDFISRAMGYVGVPLVDTLISPRGYRMLSKIPRIPATVMDNLVKNFKELKEIMEASYEDLDRVEGIGEARARAIKNGLRRLREQIMIDNKF
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation.  The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: NU1C_NOSS1
Sequence: MNSGIDLQGTFIKSLIDLGIPPGTAKAIWMPLPMILMLIGATVGVLVCVWLERKISAAAQQRIGPEYIGPLGLLAPVADGLKLVFKEDIVPAQADPWLFTLGPILVVLPVFLSYLIVPFGQNIVITNVGTGIFLWIALSSIQPIGLLMAGYSSNNKYSLLGGLRAAAQSISYEIPLALSVLAIVMMSNSLSTVDIVNQQSDYGILGWNIWRQPLGFMIFWIAALAECERLPFDLPEAEEELVAGYQTEYSGMKFALFYLSSYVNLILSALLVAVLYLGGWDFPIPINVLANLVGVSEANPVLQVVSAALGITMTLVKAYFLVFIAILLRWTVPRVRIDQLLDLGWKFLLPVGLVNLLLTAALKLAFPVAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: DBP7_NEOFI
Sequence: MADDGLLLNFSLGDNNIIQPETKLKGGTWRDRLSAKKIAKHHAKGPRTAGDEDSTPRAPRNPNRIEVPSSRPTKRQRTDGGDSGKQQSHTHPHSNQPRQFISSLFTKNPEPQKVEEVKEEGHVEDAKPTNAPLIDGLDTFTNLGLSPSLAAHLLTKLELKAPTAIQKASISQLLKEEGDAFIQAETGSGKTLAYLLPLVQRIMALSKPGAQTDAKGQPIVHRDSGLFAIVLAPTRELCKQISVVLENLLRCAHWIVAGTVIGGEKKKSEKARLRKGLNILVATPGRLADHLDNTQALDVSNVRWLVLDEGDRLMELGFEEEIQGIVKKLDARQRPSRIPGVPTRRTTILCSATLKMSVQKLGEISLKDAVHIKADPEDEDEKARRSKEEESAYRVPAQLKQSYAVVAAKLRLVTLTAFFKRTFMRKGSVMKAIIFVSCADSVDFHFEVFTRKQAKEDGDESSDTDKSEDKPPSSPHGTIAPATAFSNPSNPVTLFRLHGSLPQNVRTSTLGAFAKNKEASVLICTDVASRGLDLPNVDLVVEYDPAFSAEDHLHRIGRTARVGRDGRALIFLQPGCEENYVEVLKRGYRDGGKALTRADANDILKRGFGGNVESGNKDWETKATDWQCEIERWALENPEYLEMARRAFQSHIRAYATHIAAERSMFNIKELHLGHLAKAFALRDRPSKINVPGLRQGKEETKKDFKAERNSAAGKKRKAGGTDLADDIPSANNTATAAQKMRAKMKEHISGANEFNLA
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp7.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CATA_NEIGO
Sequence: MTTSKCPVTHLTMNNGAPVADNQNSLTAGTRGPLLTQDLWLNEKLADFVREVIPERRMHAKGSGAFGTFTVTRDITKYTRAKIFSEVGKKTEMFGRLATVAGERGADAYTRVRGFALKFYTEEGNWDVVGNNTPVFYPDLRKFPDLNKAVKRSAHQYSSATNNWDFWALLPEALHQVTIVMSDRGIPASYRHMHGFGSHTYSLWNEAGERFWVKFHFRSQQGIKNLTNEEAAKIIADDRESHQRDLYEAIERGEFPKWTMYIQVMPEADAAKVPYHPFDLTKVWPKKDYPLIEVAEFELNRNPENFFADVEQSAFAPSNLVPGIGASPDKMLQARLFNYADAQRYRLGVNFRQIPVNRPRCPVHSNQRDGQGRATELRQPAHYEPNSFGQWSQQPDFAEPPLKINGDAAHWDYRQDDDDYFSQPRALFNLMNDAQKQALFDNTAAAMGDAPDFIKYRHIRNCYRCDPAYGEGGSKALGLTVEEPQAARATDPALGQGGLL
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: UB2D2_PIG
Sequence: MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-48'-linked polyubiquitination.  Mediates the selective degradation of short-lived and abnormal proteins.  Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.  Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6.  Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection.  Essential for viral activation of IRF3.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 D2, (E3-independent) E2 ubiquitin-conjugating enzyme D2, E2 ubiquitin-conjugating enzyme D2, Ubiquitin carrier protein D2, Ubiquitin-protein ligase D2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RNH2_STAAN
Sequence: MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPITKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_ARTOC
Sequence: MAPKQIRTIGQVSQYVCLLSKPVSPVSGQVRQFTSPVDASIPASKQKFVPSSGTYPKGFKVSGSHAGVKASNTSAPDLALVWSEEPCSAAAVFTTNKFQAAPVQVSSELIRKRNGNGIRGVIVNAGCANAVTGKKGLQDARSMSKKADECNGLKEEDSSTLVMSTGVIGQLLPIERILNKVPEAQSNLASTHAAWLRTARAICTTDTFPKLTSRSFSLPSSPDRTYSIAGMTKGAGMIHPNMATLLGIICTDAPIEAPVLQSLLSHSISRSFNSISVDGDTSTNDTVAILANGAAGGTPISSTGSKDYTAMQSILTQFTQSLAQLVVRDGEGATKFVTVRVKNSPSYTDAKCIASTIARSPLVKTALYGKDANWGRILCAVGYTPDLTPGTVVPERTSVSFKPADGSAELKLLVNGEPESVDEGRASSILQHEDLEIVVDLGGGASGEAGRGGEDAIYWFCDFSHEYVTINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SNAA_STRPR
Sequence: MTAPRRRITLAGIIDGPGGHVAAWRHPATKADAQLDFEFHRDNARTLERGLFDAVFIADIVAVWGTRLDSLCRTSRTEHFEPLTLLAAYAAVTEHIGLCATATTTYNEPAHIAARFASLDHLSGGRAGWNVVTSAAPWESANFGFPEHLEHGKRYERAEEFIDVVKKLWDSDGRPVDHRGTHFEAPGPLGIARPPQGRPVIIQAGSSPVGREFAARHAEVIFTRHNRLSDAQDFYGDLKARVARHGRDPEKVLVWPTLAPIVAATDTEAKQRLQELQDLTHDHVALRTLQDHLGDVDLSAYPIDGPVPDIPYTNQSQSTTERLIGLARRENLSIRELALRLMGDIVVGTPEQLADHMESWFTGRGADGFNIDFPYLPGSADDFVDHVVPELQRRGLYRSGYEGTTLRANLGIDAPRKAGAAA
What is the function of this protein?
Catalyzes the oxidation of the proline residue of pristinamycin IIB (PIIB) to pristinamycin IIA (PIIA).
What are the official names of this protein?
Pristinamycin IIA synthase subunit A, PIIA synthase subunit A.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family.
Protein: SYL_CLAMS
Sequence: MAHETPDTPGETYDFRAIEAEWSEVWEREQPFRTPDASDSRPRKYILDMFPYPSGDLHMGHAEAFALGDAVARYWRQQGFNVLHPIGWDSFGLPAENAAIKRGVDPREWTYANIETQKQSMKRYGLSFDWERELHTSDPEYYRWNQWLFLKMHEKGLAYRKDSWVNWDPVDQTVLANEQVLPDGTSDRSGAVVVKKKLTQWYLRITDYADRLVDDLNQLEGTWPAKVLSMQRNWIGRSIGAEVDFVVEGRDEPVTVFTTRPDTLHGATFMVVAPDSDLAAELVEGASEEVRESFRGYLERTQRLNEIERSTTDRPKTGIPLGLTAINPVNGERIPVWAADYVLADYGTGAVMAVPAHDQRDLDFARAFDLPVRVVVDTTQPVTGAIRIIPEDGELPDLEEVLPGRTGVALPGEGRLINSGSLNGLSKQPAIKRVIEQLEAEGRGRAAKNYRLRDWLISRQRFWGTPIPIVYDAEGSEIRVPEDQLPVRLPDTEGLDLTPKGKSPLAAATAWSNVPSPVDGSPATRDPDTMDTFMDSSWYWLRFLSPNDATKAFDPADADRWAPIDQYVGGVEHAILHLLYSRFITKVLFDLGYVTFTEPFSALLNQGMVLSGGSKMSKSKGGVDLGSEMDRHGVDAIRLTMAFAGPPEDDIDWEDVSPSGSAKFLARAWRLTGDITSAPEVEWKTGDEALRRVTHRFLAEAPGMLEAFKFNVVIARTMELVNAIRKTIDQGPGGGDAAVREATEVVAVALSLFAPYTAEDMWKRLGREGSVAFAGWRKADRNLLVQTTVTAVVQVDGKVRDKLEVDAKIGADELEALARETAGVRRSTAGRTIDKVIVRAPKIVSITTTPAP
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNB_HYDVD
Sequence: MAGVQRRILISRNEENLLNKGIGTKNVLGGKTTSTRTALSNISNIQRRPQLGGKVKKEDVGALEEKAPTNKSLGRMISQTNLLNEVQMKKNIQNLEDMAEVDLPINSMIDSFTDLEVDDIDLEDLGNPTLCAEYVKDIYKYMNKLEQRLVPGDYMPNQTEINFKMRSILVDWLIQVQSRFNLLQETLYLTIYILDRFLNKQNVKRAELQLVGVTAMLLASKYEEMYAPEIGDFVYITDNAYSKEKIRQMEQKMLKACEYDFSNPLCLHFLRRNSKAGAVDAQKHTLAKYLMELTLVEYEFITKLPSEVAAAALYLSMKLIDDSNWTPTLVHYSGYTEDAILPTVSKLSVLTLSMDNSKYQAVKNKYAASKFLRISRIPQLKGHVLNKFAERI
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.  Interacts with the CDC2 protein kinase to form MPF.  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis (By similarity).
What are the official names of this protein?
G2/mitotic-specific cyclin-B.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: DAPE_SHEPW
Sequence: MSQFNNSPVLALAKDLISRPSVTPLDEGCQTLMADRLKDAGFNIEDMVFEDTTNMWARKGTQSPVFCFAGHTDVVPVGDLNRWHTPPFEPVVIDDYLHGRGAADMKGSLAAMVVATERFVKKHPDHKGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWSLVGEPSSTHKLGDIVKNGRRGSLTGNLTVKGMQGHVAYPHLADNPIHKASPALDELARMKWDNGNEFFPPTSFQIANINGGTGASNVIPGTLEVMFNFRYSTEVTAEILIERVLNILDAHGLDYDINWIFNGLPFLTGDGPLLDATRDAIKKVTGLDTDPQTSGGTSDGRFIAPTGAHVLELGPVNATIHKVNECVKVSDLEQLTLCYEAILENLLCQ
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: Y021_SIFVH
Sequence: MVILNKYYSMKEEYEILNIEIKDDNLFVSVKLIRNGSVEIFNYVPIQNIPKIIKNFSLVTQKNLMDN
What are the official names of this protein?
Uncharacterized protein 21.
Protein: RL40_METVS
Sequence: MAFEEAIKRVFMKRICMKCNARNSWKAEKCRKCGYSNLRPKAKEARA
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: QUEC_RHILW
Sequence: MRTIVVCSGGLDSVSLAHKIAAEQQLIGLVSFDYGQRHRKELDFAARCAARLAVPHHIIDISAIGGHLSGSALTDDIEVPDGHYAEETMKATVVPNRNAIMLAIAFGLAAAQKADAVAVAVHGGDHFIYPDCRPGFIDAFQRMQNEALDGYASVRLLAPYVEVSKAAIVTDGEKHATPFAETWSCYKGGRLHCGRCGTCVERREAFHLAGIPDPTEYEDQDFWKAAVSQYSAAEVR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: GREA_BACAC
Sequence: MATEKTYPMTQEGKQKLENELEDLKTVKRKEVVERIKIARSFGDLSENSEYDAAKDEQAFVEGRITQLENMIRNAVIITDNGEESTVVTLGKTVTFKELPNGDEEAYTIVGSAEADPFEGRISNDSPIAKSLLGKQIGEKVAIQTPGGEMQVEIISVK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RL5_LYSSC
Sequence: MSRLKEKYLNEVSPALMSKFGYKSVMQLPKVEKIVINMGVGDAVQNSKALDAAVEELTIITGQKPVVTKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDKLISISLPRVRDFRGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANSDEEARELLTQFGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NAGK_PECAS
Sequence: MYYGFDMGGTKIELGVFDAELNKVWQKRVPTPRNNYDDLLAMLIDLVHEADAQVGVQGSVGIGVPGIQTGDEGALFTANLPATMGKPLRIDLSQRLQRDVRISNDANCFVLSEAWDAEFRSYPVVLGLILGTGLGGGLVINGRPVDGRNGIAGEFGHLRLPSDALDIIGVDIPRVKCGCGQFGCIENYISGRGFEWLYEHLYGEALPAVTIIRHYRGGEEKALEFVDRFMDLLAACLGNLLTLFDPHLLVLGGGLSNFDEIYQILPTRLPSRLLPIAKLPRIEKARHGDAGGVRGAALLHLMDN
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: NUDC_SALTY
Sequence: MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQEAGLFQLAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYD
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: RUVA_PSEA8
Sequence: MIGRLRGTLAEKQPPHLILDVNGVGYEVEVPMTTLYRLPSVGEPVTLHTHLVVREDAHLLYGFAEKRERELFRELIRLNGVGPKLALALMSGLEVDELVRCVQAQDTSTLVKIPGVGKKTAERLLVELKDRFKAWENMPTIAPLVMEPRASATVSSAEADAVSALIALGFKPQEASRAVAAVPGEDLSSEEMIRQALKGMV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MOSA_AZOVD
Sequence: MTDTTNSIKHVISPLARQTLQDRDLTRPVAGKRPIRLLPWLQVVKIGGRVMDRGADAILPLVEELRKLLPEHRLLILTGAGVRARHVFSVGLDLGLPVGSLAPLAASEAGQNGHILAAMLASEGVSYVEHPTVADQLAIHLSATRAVVGSAFPPYHHHEFPGSRIPPHRADTGAFLLADAFGAAGLTIVENVDGIYTADPNGPDRGQARFLPETSATDLAKSEGPLPVDRALLDVMATARHIERVQVVNGLVPGRLTAALRGEHVGTLIRTGVRPA
What is the function of this protein?
Intracellular storage of molybdenum.  Binds polyoxomolybdates.  Can bind at least 90 molybdenum atoms per protein molecule.
What are the official names of this protein?
Molybdenum storage protein subunit alpha, Mo storage protein subunit alpha, MoSto subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family. Highly divergent.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_CAUVC
Sequence: MNDLKRSLSEAAAAAFQAAGLPPEFGRVTASDRPDLADFQCNGALAAAKSAKRNPREIAVQVVDILKGDPRLASVEIAGVGFINMRVSDEALSARAREIASDDRTGAQLLETPRRVLIDYAGPNVAKPMHVGHLRASIIGESVKRLYRFRGDDVVGDAHFGDWGFQMGLLISAIMDEDPFINALMEKLPEAPRGFSSADEAKVMAEFEKRITLADLDRIYPAASVRQKEDPAFKERARKATAELQNGRFGYRLLWRHFVNVSRVALEREFHALGVDFDLWKGESDVNDLIEPMVLQLEAKGLLVQDQGARIVRVAREGDKRDVPPLLVVSSEGSAMYGTTDLATILDRRKSFDPHLILYCVDQRQADHFETVFRAAYLAGYAEEGALEHIGFGTMNGADGKPFKTRAGGVLKLHDLIEMAREKARERLREAGLGAELSEEQFEDTAHKVGVAALKFADLQNFRGTSYVFDLDRFTSFEGKTGPYLLYQSVRIKSVLRRAAESGAVAGRVEIHEPAERDLAMLLDAFEGALQEAYDKKAPNFVAEHAYKLAQSFSKFYAACPIMSADTETLRASRLTLAETTLRQLELALDLLGIEAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_STRGG
Sequence: MHVTHLSLADFRSYARVEVPLDPGVTAFVGPNGQGKTNLVEAVGYLATLGSHRVSSDAPLVRMGAERAVIRAAVTQGERSQLIELELNPGRANRARINRSSQVRPRDVLGIVRTVLFAPEDLALVKGDPGERRRFLDELITARSPRMAGVRSDYERVLKQRNTLLKSAAMARRHGGRSMDLSTLDVWDQHLGRVGAELLAQRLDLIATLQPLADKAYGDVAPGGGPVALEYRSSVGGDVGPARTRDELYEQLTAALVGVRKQEIERGVTLVGPHRDDLLLGLRGMPAKGYASHGESWSYALALRLASYELLRSEGNEPVLVLDDVFAELDARRRERLAELVVPGEQVLVTAAVAEDVPGVLAGARYAVSAGEVARV
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRE_GLAP5
Sequence: MEHYLSLFVKSIFIENMALSFFLGMCTFLAVSKKVSTAFGLGIAVIVVLGIAVPANQIVYENILKDGALVEGVDLTFLNFITFIGVIAALVQILEMILDKFFPALYSALGIFLPLITVNCAIFGAVSFMVQREYNFAESVVYGIGAGTGWMLAIVALAGITEKMKYSDVPAGLKGLGITFISAGLMALGFMSFSGIKL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPX_CHLFF
Sequence: MNKKNLTICSFCGRSEKDVEKLIAGPSVYICDYCIKLCSGILDKKPTSTPTSGASTEAAPQHPDLQVLTPKEIKKHIDQYVVGQERAKKTIAVAVYNHYKRIRALLNNKHVSYGKSNVLLLGPTGSGKTLIAKTLAKILDVPFTIADATTLTEAGYVGEDVENIVLRLLQAADYDVARAERGIIYIDEIDKIGRTTANVSITRDVSGEGVQQALLKIIEGTTANVPPKGGRKHPNQEYIRVNTENILFIVGGAFVNLDKIIAKRLGKTTIGFSDDLGDFSQKDRDHLLTKVETEDLIAFGMIPEFVGRFNCIVNCEELSLDELVAILTEPTNAIIKQYIELFSEENVKLIFEKEALYAIAKKAKLAKTGARALGMILENLLRDLMFEVPSDPTVEAIRIQEDTILENKAPVIIRRAPEAIA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: LEU1_BACVZ
Sequence: MRKINVFDTTLRDGEQSPGVNLNSREKLAIAKQLERLGVDIIEAGFPASSRGDFLAVQEIARTIKNCSVTGLARSVKGDIDAAWEALKDGVSPRIHIFIATSDIHLKHKLKMTREEVKEKAVEMVKYAKERFPIVQWSAEDACRTELPFLAEIVEEVIDAGASVINLPDTVGYLTPDEYGNIFKYMKEHVPNISRVKLSAHCHDDLGMAVANSLSAIENGADQIECAINGIGERAGNAALEEIAVALHVRNDAHQADSSLNLHELKRTSDLVSKLTGMAVPRNKAIVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKDRLNTLGFQFDSDEINKYFTMFKELTEKKKEITDDDLISLILEEKVTDKKIGYEFLSLQVHYGTSQVPTATVSLKNQENEQLMQEAATGAGSVEAVYNTLGRCIDKNIELTDYRIQSNRKGEDALAQVFVRVTVNGKESSGRGIAQDVLEASAKAYLNAVNRQLVLDCNLDGLKRQTAVGS
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.