PharMolix/UniProtQA huggingface dataset:
Protein: MCBA_ECOLI
Sequence: MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATGASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTATIYK
What is the function of this protein?
Affects biofilm formation and mucoidy.
What are the official names of this protein?
Uncharacterized protein McbA, MqsR-controlled colanic acid and biofilm protein A.
What is the protein family that this protein belongs to?
Belongs to the BhsA/McbA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YIBT_SHIFL
Sequence: MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPDESVPLYLQRLEYYRRLYRPKQVEGQ
What are the official names of this protein?
Uncharacterized protein YibT.
Protein: CC148_HUMAN
Sequence: MCAASASPDNLVFHMKNEMRNIKYKPVDYQQLRALTEAKKLASASAKLKIRKAMLTSKLSKEQTLIKQHKQVWWQEYQRLNEVRCKMESEIKSLLNEENIGNECLCDLTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEFNSMKVLEEVDFVKKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPYPDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIYRNCQLSEEDHWIYQAILDQYPGDLFGRRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNKKDFIQKAVLTLTEACATHEMESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSDTMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELALREAGLHRTLYAKEILPKISPQKPPRKDMESTVFKI
What are the official names of this protein?
Coiled-coil domain-containing protein 148.
Protein: RL14_SHEON
Sequence: MIQMQSTLDVACNSGARRVQCIKVLGGSHRRYAGIGDIIKVSVKEAIPRAKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNNNLQPIGTRIFGPVTRELRNEQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TCAA_STAAR
Sequence: MKSCPKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNNIKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTKDNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRVSKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKMVIAEANKVTPIGNFIPGTYRIPAMKSTENGDFAGHLKFDFRQSNSETVDVTEDFEEANITVTLKGDTKLNDSSKKVTINDREMAFSSSKTYGPYPQNKDITISASGKAKGKTFTTQTKTIKASDLKYNTEITLNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSSFYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLVNENGKQVDKEYELEQGPQDRLQLIKTSEK
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HRCA_LEPIC
Sequence: MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDFGYLASKHTSGGRIPTERGYRFYVDSLVILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSNAAGIVIGPAKNLDTLKHIELIHVRGDEILMILVMRSGTVLHRNIFVDQNYSQEALYQVSKYLNDNLKGYDIYEIQNVIIPKLMIRKDGPEDFIRIADLISSAMTPDNSEVTLYIDGFKNLYANFRDEEQQLSQVLSLLDDQGFLKAFFSEYIDQDGVFTIIGKDGDRSMSGVSIITSNYKMGEKKIGALGIIGPQRMDYNRALPLVDFTSKLVSEMVTRISK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: STP2_PANTR
Sequence: MDTKTHSLPITHTQLHSNSQPQSCTCTRHRQTFSQSCRQSHCGSRSRSSSQSPASHRNPTGAHSSSGHQSQSPNTSPPPKRHKKTMNSHHSPMRPTILHCSCPKNRKNLEGKLKTKKMAKRIQQVYKTKTRSS
What is the function of this protein?
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals.  In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
What are the official names of this protein?
Nuclear transition protein 2, TP-2, TP2.
What is the protein family that this protein belongs to?
Belongs to the nuclear transition protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids (By similarity). Nuclear import is mediated by IPO4. Nucleolar localization requires the protein to be phosphorylated (By similarity).
Protein: KDSA_PSEPF
Sequence: MAQKIIRVGDIEIANDKPMVLFGGMNVLESRDMAMQVCEEYVKVTEKLGIPYVFKASFDKANRSSVTSYRGPGLEEGMRIFQDIKQAFGVPIITDVHEPDQAAVVAEVCDIIQLPAFLSRQTDLVVAMAKTNAVINIKKAQFLAPQEMKHILNKCVEAGNDQLILCERGSSFGYNNLVVDMLGFGIMKQFEYPVFFDVTHSLQMPGGRSDSAGGRRAQVTDLAKAGMSQSLAGLFLEAHPDPDNAKCDGPCALRLDKLEPFLAQLKALDELVKSFPTVETA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH40_MOUSE
Sequence: MTLGLEQAEEQRLYQQTLLQDGLKDMLDHGKFLDCVVRVGEREFPCHRLVLAACSPYFRARFLAEPDSAGEVRLEEVSPDVVSQVLHYLYTSEIALDEASVQDLFAAAHRFQIPSIFTICVSFLQKRLCLANCLAVFRLGLLLDCARLAVAARDFICARFPLVARDNDFLGLSADELIAIISSDGLNVEKEEAVFEAVMRWASSGDAEAQAERQRALPTVFESVRCRLLPRAFLETRVERHPLVRSQPELLRKVQMVKDAHEGRLTTLRKKKKEKGEQTARAKEANQGTEDTKAEDDEERVLPGILNDTLRFGMFLQDLIFMISEEGAVAYDPAANECYCASLSTQIPKNHVSLVTKENQVFVAGGLFYNEDNKEDPMSAYFLQFDHLDSEWLGMPPLPSPRCLFGLGEALNAIYVVGGRELKDSEDSLDSVLCYDRLSFKWGESDPLPYAVYGHTVLSHMDLVYVIGGKGKDRKCLNKMCVYDPKKFEWKELAPMQTARSLFGATVHDGRIFVAAGVTDTGLTSSSEVYSIADNKWTSFEAFPQERSSLSLVSLAGTLYALGGFATLETESGELVPTELNDIWRYNEDEKKWEGVLREIAYAAGATFLPVRLNVVRLTKM
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development (PubMed:25940086).  The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (PubMed:25940086).  Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (PubMed:24960163).
What are the official names of this protein?
Kelch-like protein 40, Kelch repeat and BTB domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the KLHL40 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, myofibril, sarcomere, I band.
Protein: CYSZ_PECAS
Sequence: MSSEKSSFPEKPPSFEKPSHSNTADHTRSGVHYFFAGWRLISLPGIRRFVILPLLMNIVLMGGAFWWLFTQLNDWIPQIMSHIPSWLQWLSYLIWPLAVLSILLVFSYLFSTIANFIAAPFNGLLAEQLEAKLTGQTLPDSGILSIAKDVPRIMKREVQKLAYYLPRAIVLLLLYFIPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVGFSTMRQALRRHKVANMQFGALVSLFTLVPFLNLVIMPVAVCGATQLWVDRYRNLSATLPKKSP
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DCDA_HELPJ
Sequence: MFNYEELFQTYKTPFYLYDFDKIKQAFLNYKEAFKGRKSLICYALKANSNLSILSLLANLGSGADCVSIGEIQRALKAGIKPYKIVFSGVGKSAFEIEQALKLNILFLNVESFMELKTIETIAQSLGIKARISIRINPNIDAKTHPYISTGLKENKFGVEEKEALEMFLWAKKSAFLEPVSVHFHIGSQLLDLDPITEASQKVAKIAKSLIALGIDLRFFDVGGGIGVSYENEETIKLYDYAQGILNSLQGLDLTIICEPGRSIVAESGELITQVLYEKKAQNKRFVIVDAGMNDFLRPSLYHAKHAIRVITPCGGREISPCDVVGPVCESSDTFLKDANLPELEPGDKLAIEKVGAYGSSMASQYNSRPKLLELALEDHKIRVIRKREALEDLWRLEIEGLEGV
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: RPOZ_METEP
Sequence: MARVTVEDCIEKVENRFELVLLASHRARLLAAGAPLTVERDRDKNPVVALREIGDETITAEDLKEQLIHSMQKYVEVDEPEAETVPLLSSSPAAAAVAPQSSSDDKNVQFDFMSEEDLLRGLENLAPPTETDDEGE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: LIPA_SODGM
Sequence: MSKPIQMERGVKYRDADKMALIPIKTVAVERQEILRKPSWMKIKLPADSTRIQGIKVAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVTPDANEPEKLAQTIADMGLRYVVVTSVDRDDLRDGGAQHFADCISAIRAKNPNIRIETLVPDFRGRMDRALEIINAAPPDVFNHNLENVPRLYRQVRPGADYHWSLKLLENFKVANPQLPTKSGLMVGLGETNAEIVDVMRDLCRHGVTMLTLGQYLQPSRHHLPVKRYVSPQEFDEMKQEALAMGFTHAACGPFVRSSYHADLQAKGIEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STE20_TALMA
Sequence: MSLKKQQQQSDFSAAPARRPPTLQSYHTSPDPRGKQILRQSASFTALNNPRMDTALPQIQDAPSNSKRNSDEGFGTKPRRKNTFSSFVNSVLGSPRNIKISAPENPVHVTHVGYDNQTGQFTGLPKDWQRMLQASGISKKEQEQHPQTMVDIMRFYERNAAGAGDEEVWHKFDNAILRQGEYPDGMSPASATSPRFPQNHEGSFENPRAAPPPPKPSQSSPVPVLSSTIVPNRVAPKPPTVGLIPSRPPPQPPVVSNRAPAARPANEPVTTPPIPENEPVFVNAPPVVPSAIQSPVQYQQQQERAMAAAQQAIIDKQLDRSRSQPAAAVARPRPRTRQSTAFDVRAKLQAICTPGDPTKKYYNLNKIGQGASGGVFTAYETNTNKCVAIKQMNLDLQPKKDLIINEILVMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRETLSGLQHLHSKGVIHRDIKSDNILLSMDGEIKLTDFGFCAQINDSQNKRNTMVGTPYWMAPEVVTRKEYGRKVDIWSLGIMAIEMIEGEPPYLTESPLRALYLIATNGTPKIKDEQNLSPVFRDFLHLALRVDPEKRASAHDLLKHPFMSICEPLNSLAPLVKSARISRAQEKAQKGGA
What is the function of this protein?
MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle.
What are the official names of this protein?
Serine/threonine-protein kinase pakA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DTD_HALH5
Sequence: MKVVLQRAKQAQVTVEGETVGAIDHGLVLLIGITHGDTEEDARYLAEKIAHLRIFEDEGGKMNQSVKDVGGAILSISQFTLYGDCRKGRRPNFMEAAKPEHAEPLYETLNSHLEQLGLHVETGRFGAMMDVQLINDGPVTLLVESK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
Protein: HEM3_FRAP2
Sequence: MKQIVIASRESKLALWQTNYVKDRIQQELNIRCQINTMKTQGDIILDKPLNKIGGKALFMKELEIAMLNNKADIAVHSLKDVPYQLPQGFCLSSFMPREDPRDAFVSNKYSSIDDLPRGAIVGTSSLRRKAQLLHYRYDLEIRDLRGNVQTRLSKLDNGDYDAIILASAGLIRLELNERITQFIPVEISLPAVGQGIVVIEALDKSSEILQKLQKLNCSDSFCVATAERAFNQELKGGCHVAIGAYAELHDNQITLTAMVASSDGKNILKRKLTGDDPMRLGKLLAQEMIELGAYKILEK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: F16P_DICDI
Sequence: MSSNNLITLHRWLLSDTHKNMENKLEMANLFSGIALACKITNNAIKRAGFESNFGLAGITNVHSEDVKKLDVIANDAFKMALKSTREVFCMVSEEEDSIIPVSQSQAGKYVVAFDPLDGSSNLDCNVSVGSIFSIWPKASKDHNYSNDDVLRKGRDMTAAGYALYGSATMLVLTFGQGVYGFTLDNHIGEFVLTHVEMRIRTKGSIYSINEGNSVFWDKATQEYVKAIKSGADGRAPYSSRYIGSMVSDIHRTLLYGGIFMYPGDTKSPNGKLRYLYEVAPLSFIMEQAAGKSTNGSSPCLDMIPKSIHERVPVFMGSPACIDELLAFQKKFNHNHSTTSQHEKDN
What are the official names of this protein?
Fructose-1,6-bisphosphatase, FBPase, D-fructose-1,6-bisphosphate 1-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
Protein: YCF3_MORIN
Sequence: MSRSRINGNFIDKTFSIVANILLRIIPTTSGEKEAFAYYRDGMSAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTRNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEIAEAWFDQAAEYWKQALALTPGNYIEAQNWLKITGRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RS9_BREBN
Sequence: MAQVQYYGTGRRKHSVARVRLVPGEGRIVINKREMDTYFGLETLKLIVKQPLVLTETLGRYDVLVNVNGGGTTGQAGAIRHGVARALLKADPELRGALKRAGFLTRDPRMKERKKYGLKAARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: UXAC_STRE4
Sequence: MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKVYDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWSVMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDDLAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAMEERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVFAELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHLVQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQMNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGKMAQDIAYNNAIQYFN
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: LEUD_BACCZ
Sequence: MEPFRIHKGTAAVLMNDNIDTDQIIPKQYLKRIERTGFGKFLFDEWRYDNERHENPNFPLNAPDRKGASILITGDNFGCGSSREHAPWALADYGFRVIIAGGFADIFYMNCMKNGMLPIVMDKDMRENLTKTDAREQIEVDLENEVITTSTHRFHFTIEKMWKEKLLNGLDEISITMQYEQEIREYERKVAVY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RBL_CERGU
Sequence: VGFKAGVKDYKLTYYTPDYETKDTDILAAFRVSPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYSI_PSEA6
Sequence: MTTDNKFVVEGKLADNERLKGESNFLRGTIAEDLKDDLTGAFVGDNFQLIRFHGMYQQDDRDLRAERAKQKLEPLQNVMLRARLPGGIIKPQQWLAIDKFAEEKSLYGSIRLTTRQTFQFHGVLKPNIKLMHQTLNQVGIDSIATAGDVNRNVLCTSNPIESAVHQEAYEWATKISEHLLPKTRAYAEIWLDGEKKETTDHEPILGANYLPRKFKTTVAIPPLNDVDVHANDLNFIAISKDGKLVGFNVLVGGGLAMTHGDHATFPRKASDFGFIKVEDTLAIAEAVVSTQRDWGNRVNRKNAKTKYTLERVGVENFKAEVEKRSGVTFGESQAYEFTERGDRIGWVEGIDGKHHLTLFIENGRILDYPGKPLKTGCAEIAKIHDGDFRLTANQNLIVAGVSEQNKAKVEEIARAHGLIEDDLSAQRKDSMACVALPTCPLAMAEAERYLPEAVTQLEGILAKHAIAQKSIIYRVTGCPNGCGRSMLAEIGLVGKGPGKYNLHLGGNRQGTRIPKMYKENIGEQQIMDELDVLIGQWAKEAQSDESFGDFVIRTGVIAEVVNSAEDFYA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: APT_SHEPC
Sequence: MMAMNTETLSLIKQSIKTIPNYPKEGILFRDVTSLLENAAAYKAAIDLLVEHYRGQGFTKIVGTEARGFLFGAPLALELGIGFVPVRKPGKLPRATISQSYELEYGHDSLEIHTDAISANDKVLVVDDLLATGGTIEATVKLIRQLGGEVKDAAFVISLPDLGGEARLTALGLELVKLCEFEGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_ALIF1
Sequence: MIPGELRVNDDLGQIELNVGRTTQTLSVANYGDRPIQVGSHYHFYEVNEALHFDREATKGFRLNIPAGMAIRFEPGQRRTIELVEFAGKREIYGFQAAIMGNVDKHITTTIPDDKEVK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFWD3_HUMAN
Sequence: MAHEAMEYDVQVQLNHAEQQPAPAGMASSQGGPALLQPVPADVVSSQGVPSILQPAPAEVISSQATPPLLQPAPQLSVDLTEVEVLGEDTVENINPRTSEQHRQGSDGNHTIPASSLHSMTNFISGLQRLHGMLEFLRPSSSNHSVGPMRTRRRVSASRRARAGGSQRTDSARLRAPLDAYFQVSRTQPDLPATTYDSETRNPVSEELQVSSSSDSDSDSSAEYGGVVDQAEESGAVILEEQLAGVSAEQEVTCIDGGKTLPKQPSPQKSEPLLPSASMDEEEGDTCTICLEQWTNAGDHRLSALRCGHLFGYRCISTWLKGQVRKCPQCNKKARHSDIVVLYARTLRALDTSEQERMKSSLLKEQMLRKQAELESAQCRLQLQVLTDKCTRLQRRVQDLQKLTSHQSQNLQQPRGSQAWVLSCSPSSQGQHKHKYHFQKTFTVSQAGNCRIMAYCDALSCLVISQPSPQASFLPGFGVKMLSTANMKSSQYIPMHGKQIRGLAFSSYLRGLLLSASLDNTIKLTSLETNTVVQTYNAGRPVWSCCWCLDEANYIYAGLANGSILVYDVRNTSSHVQELVAQKARCPLVSLSYMPRAASAAFPYGGVLAGTLEDASFWEQKMDFSHWPHVLPLEPGGCIDFQTENSSRHCLVTYRPDKNHTTIRSVLMEMSYRLDDTGNPICSCQPVHTFFGGPTCKLLTKNAIFQSPENDGNILVCTGDEAANSALLWDAASGSLLQDLQTDQPVLDICPFEVNRNSYLATLTEKMVHIYKWE
What is the function of this protein?
E3 ubiquitin-protein ligase required for the repair of DNA interstrand cross-links (ICL) in response to DNA damage (PubMed:21504906, PubMed:21558276, PubMed:26474068, PubMed:28575657, PubMed:28575658).  Plays a key role in RPA-mediated DNA damage signaling and repair (PubMed:21504906, PubMed:21558276, PubMed:26474068, PubMed:28575657, PubMed:28575658, PubMed:28691929).  Acts by mediating ubiquitination of the RPA complex (RPA1, RPA2 and RPA3 subunits) and RAD51 at stalled replication forks, leading to remove them from DNA damage sites and promote homologous recombination (PubMed:26474068, PubMed:28575657, PubMed:28575658).  Also mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint (PubMed:20173098).  May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome (PubMed:20173098).  In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53 (PubMed:20173098).
What are the official names of this protein?
E3 ubiquitin-protein ligase RFWD3, RING finger and WD repeat domain-containing protein 3, RING finger protein 201.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Cytoplasm. Note=In undamaged cells, found both in the cytoplasm and in the nucleus, partially associated with PML nuclear bodies (PubMed:21558276). In response to replication block, such as that caused by hydroxyurea treatment, or to DNA damage caused by ionizing radiations or doxorubicin, recruited to the nucleus, to stalled replication forks or to sites of DNA repair (PubMed:21504906, PubMed:28575657). This recruitment depends upon RPA2 (PubMed:21504906).
Protein: AIM44_LACTC
Sequence: MIRTPTRTKTLSFAGPQVDFHFPSPESAPNGSLDNYHMSNHHLLNDAVARSPSQNSSGTSNGVDSAHYSFANISDNTTGVRNAGNGKRSSQAPSWSSGSGSCRRYPVTLAPITNASALARPGDSGAADVRKNDTAAFLRRKRSPEDCALHSISTSAYTIPTADNISFQITFGSSDKSHSLGSLRRSPSFGRRLPSRRTAGSSNNAPVSASLPARAASVKSTQSTLKRSQAVRCKGGLLQFFMQVGVRAKNRIRRWRLAVRKKLFTYKAKRLAKKNKKQTTSHLKRGNGYVSNIQRSISSASLRNSQRKNSDSASKETPATVARSGTLPNPLETPPKTTRKSLRRSPSSIKRAASILTRANSSGTITQGTAEKNNAGENIPRTKLVRSGPSLSLSSIARQPSIVVNNKVIPLTSLNEDTKDFTIEEEDEDEYVIDTDCMKKSVRGYSQSSSGSSNSGKSSDETYHDSLENPTPDESLLPDEKVSRALDAWNHYLRAVVAQRVLMRLQIRRFQESGGDPECQELIDAIISDYEENSSSHCDSDLRSDSTSLTSVSDCEGRVSSSVASDVSVGITGSIFSARPFQQTMKNSVKRSLTLPVGFRV
What are the official names of this protein?
Altered inheritance of mitochondria protein 44.
What is the protein family that this protein belongs to?
Belongs to the AIM44 family.
What are the subcellular locations of this protein?
Bud neck.
Protein: ACCD_STAAW
Sequence: MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNNMRQTLSEILKIHQEVTK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBGP9_SOLMC
Sequence: MKTFVLHIFIFALVAFASASRDSARKIGSQYDNYATCLAEHSLTEDDIFSIGEVSSGQHKTNHEDTELHKNGCVMQCLLEKDGLMSGADYDEEKMREDYIKETGAQPGDQRIEALNACMQETKDMEDKCDKSLLLVACVLAAEAVLADSNEGA
What is the function of this protein?
Colony queen number, a major feature of social organization, is associated with worker genotype for Gp-9.  Colonies are headed by either a single reproductive queen (monogyne form) or multiple queens (polygyne form).  Differences in worker Gp-9 genotypes between social forms may cause differences in workers' abilities to recognize queens and regulate their numbers (By similarity).
What are the official names of this protein?
Pheromone-binding protein Gp-9, PBP, Putative odorant-binding protein Gp-9.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
What are the subcellular locations of this protein?
Secreted.