PharMolix/UniProtQA huggingface dataset:
Protein: INSY1_RAT
Sequence: MNIRGAPDLGQPSDDPNSGGERERIRQRMKMVIGQLEGILRELKEVAKELREVVSQIDKLTSDFDFELEPDDWTTATVSSTSSSDKAGAGGPFDLGHLDFMTADILSDSWEFCSFLDVSTPSDSVDGPEAPRPGTGPDYQLMNGGLPIPNGPRVETPDSSSEEAFSAGPAKGQVPQRTPGTRERVRFSDKVLYHALCCDDEEGDGEEVEEEEAGLAPELPRVEPHTGPLKPSPAPYKTKRSPLTTRRLGPTLAPEQTRRVTRNSSTQTVSDKSTQTVLPYTATKQKAKGKN
What is the function of this protein?
Component of the protein machinery at the inhibitory synapses, probably acting as a scaffold.  Inhibitory synapses dampen neuronal activity through postsynaptic hyperpolarization.  This synaptic inhibition is fundamental for the functioning of the central nervous system, shaping and orchestrating the flow of information through neuronal networks to generate a precise neural code.
What are the official names of this protein?
Inhibitory synaptic factor 1, InSyn1.
What is the protein family that this protein belongs to?
Belongs to the INSYN1 family.
What are the subcellular locations of this protein?
Postsynaptic density.
Protein: ARREH_SHIFL
Sequence: MRLRHLSDPDSLPALDKSFAIERPALGLAPDAPPVRILLLYGSLRARSFSRLAVEEAARLLQFFGAETRIFDPSDLPLPDQVQSDDHPAVKELRALSEWSEGQVWCSPERHGQITSVMKAQIDHLPLEMAGIRPTQGRTLAVMQVSGGSQSFNAVNTLRLLGRWMRMFTIPNQSSIAKAFQEFDAAGRMKPSPYYDRIADVMEELVRFTALVRPHREALTDRYSERKAAGHVIDEATDLSSIAIAPQPLPESETS
What is the function of this protein?
Has NADPH-dependent FMN reductase activity and very low azoreductase activity.  No activity with NADH.
What are the official names of this protein?
NADPH-dependent FMN reductase ArsH, Arsenical resistance operon protein ArsH.
What is the protein family that this protein belongs to?
Belongs to the ArsH family.
Protein: IHFA_ECO5E
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MSRA_METBU
Sequence: MERATFAAGCFWGVEAAFSKVEGVISTKVGYTGGTLKDPTYKDVSTGSTGHAESIDIIFDESVITYGELLEVLWNTHDPTTKDSQGPDHGSQYRSAIFYHDDAQREAALRSREQLERSGKYDSTIKTEIVKASEFSPAEDYHQKYFQKLQFKR
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: NESD_DROME
Sequence: MEVFTFEKSYLERLKEAEAVLSWEGAVMPASQVRSEWKSYVELKIEPAGWQAIWKIPRVICEDLKLRYPTIVYGYVEQVIFDELKAVFVVTAVQDSDVHLPESNEVSLVELWPTVQQENAALNVDTTAECIDRLRFFYTHVWMPWDKDYDDDRDWVQQHLQARIQLVCDLSKNRLPRPLALHMRTLLAEAKYIQQRLDYLELDLSDAESDDEAVELNDSVAEPARKQSKAGSANGCLNVSSLPVTDLMCLHLRMAIIRSEFEILENPEMRRAYSELQSNSLKRLRCSSGRTRQSEDLLVERNSISHVVTLPGKLQQQLELLKLAQTLVKPESKVQLSNTLQDVLSICQSNDDILLSPGEHTIKFLEHLNDNGSLRGLTQPEAILSPAADLSLLPVVCSSDEDSTLLVIDGDYTLSELVLDCRHVRRGILLRNGTLTMRGCRLLGDGSSSTQEGIVCMPGASVELKSCLIENFAVGVSMRPKSSAELGSVQFKTCKTGLELLEKSASVNLQGSKCSFENCALGILADGFVLGEQRTEKVLVLNKFSELQRYNEDNLLGNCSFYNCKKNVRVFNESGQLLAQRSHQQLLEDELGGENKENIQLV
What is the function of this protein?
Required during male meiosis for completion of spermatocyte cytokinesis and possibly also required in female germline cells.  Also involved in ring canal formation in male and female germline cells.  Not essential for cleavage furrow ingression but is required for contractile ring stability and the attachment of the furrowing membrane to the actomyosin ring in late telophase.  Displays high binding affinity for beta-galactosides.
What are the official names of this protein?
Protein nessun dorma.
What are the subcellular locations of this protein?
Midbody. Note=Detected in the midbody in late cytokinesis. Also detected in ring canals in testis and ovary and in the fusome.
Protein: OAF_DROME
Sequence: MILKEEHPHQSIETAANAARQAQVRWRMAHLKALSRTRTPAHGNCCGRVVSKNHFFKHSRAFLWFLLCNLVMNADAFAHSQLLINVQNQGGEVIQESITSNIGEDLITLEFQKTDGTLITQVIDFRNEVQILKALVLGEEERGQSQYQVMCFATKFNKGDFISSAAMAKLRQKNPHTIRTPEEDKGRETFTMSSWVQLNRSLPITRHLQGLCAEAMDATYVRDVDLKAWAELPGSSISSLEAATEKFPDTLSTRCNEVSSLWAPCLCNLETCIGWYPCGLKYCKGKGVAGADSSGAQQQAQPTNYRCGIKTCRKCTQFTYYVRQKQQCLWDEXRRGELQLMQMRCARRRNGSEFGDDASATCPGGETRAATTTATITGGGAGGSGKDTTAATTTTTNKLRQLLLLVQQQMPFALWSFPVHHISQSHHQSQSQHKPSRQQKQHQHHSQVAPTSHHQSSSSTPPTPSTSSSPPSSSSSSSSSAMAAIVA
What is the function of this protein?
Vital for proper neuronal development and hatching.
What are the official names of this protein?
Out at first protein.
What is the protein family that this protein belongs to?
Belongs to the OAF family.
Protein: POTA_ONYPE
Sequence: MKTLIILKDLTKVFDNQLILRGINLEIKQNEFVTLLGPSGCGKTTILRILGGFENPSSGEVLFQEKSILNVAAHKRPINTVFQKYALFPHLNVFENVAFGLRLKDFNSKIKANLSLNKTHYQTNKANLSKTFHQELTKDLTQEKTTQITHNFNNQIETLTKDFETKQTALKCKKINKKEQEEQIQKEVLKYLKIMGLQGLEKRTIEQLSGGQQQRVAIARALINKPQVLLLDEPLSNLDLKLKQEMQYELKEIQKNSGITFLFVTHDQEEAFTMSDKVVVMNHGEIQQIGSPEDIYNEPANRFVAQFVGESNLIKGVMKDDFLVHFDNQTFNCVDKGFRKEENVDIVIRPEDIDIVSQGKGLITGIVQSIIFKGVHWEIDVKTAQRTYTIHTTDHVELNKQVDITFNPEDIHVMEIW
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NAGZ_PSEA8
Sequence: MQGSLMLDIGGTWLTAEDRQILRHPEVGGLIIFARNIEHPAQVRELCAAIRAIRPDLLLAVDQEGGRVQRLRQGFVRLPAMRAIADNPNAEELAEHCGWLMATEVQAVGLDLSFAPVLDLDHQRSAVVGSRAFEGDPERAALLAGAFIRGMHAAGMAATGKHFPGHGWAEADSHVAIPEDARSLEEIRRSDLVPFARLAGQLDALMPAHVIYPQVDPQPAGFSRRWLQEILRGELKFDGVIFSDDLSMAGAHVVGDAASRIEAALAAGCDMGLVCNDRASAELALAALQRLKVTPPSRLQRMRGKGYANTDYRQQPRWLEALSALRAAQLID
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAR1_DANRE
Sequence: MATYGNETVDNYLYSSYNPYYYKYPKFKGWRQKAYFTNYGEGETYFDNHHRAQLKSILSQINPNLTPRLRKANTKDVGVQVNPKTDASIQCSLGPRTLLARKRDALRRRRQEVQTPGSPVSSGGVRFPRTQAVYSPVESRRLVSLFREEGEEEEDTDLEVTETVDSAEKLESAEKNVRKQGKKSAKQPLSPEKNINKQTETNEENTNEPVKTEQDDLKSKARVRFQSLEQKYGFYHCKDCNLRWESAYVWCVQGTNKVYFKQFCRTCQKSFNPYRVEDIACQTCKKARCTCSVKSRHVDPKRPHRQDLCGRCKGKRLSCDSTFSFKYII
What is the function of this protein?
mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation (PubMed:27913641).  Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (By similarity).  Binds to the 3'-UTR of zona pellucida mRNAs, inhibiting their translation (PubMed:27913641).
What are the official names of this protein?
Zygote arrest protein 1.
What is the protein family that this protein belongs to?
Belongs to the ZAR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_PROMA
Sequence: MKNISAGHNALMVLGTSSGAGKSIITTAICRSLLRKGEVPIPFKGQNMSNNAWVDINNGEMAYSQAVQAWAAGIEPICAMNPVLLKPQGDCTSEVIHLGKSVGVVQAANYYEDWFSSGWEAIQKGLNDIATSYKKHRLILEGAGSPVEINLQHRDLTNLKLAKHLNAKCVLVADIERGGVFAQIIGTLALLKPDEKALIQGIIINRFRGDISLFEKGRQWIEEESKIPVLGIMPWLNEIFPPEDSLDLLERKHKKTKAEIQIAVIKLPSLSNFADLDPLEAEPTIQLNWIQPGDYLGNPNAVIIPGSKQTLKDLQSLQSSGLGNQIKEFASSGGTVFGICGGLQILGEKLEDPLGIEQSFLETSISELEGLSLIPIKTIFHSKKSLTKKDVISKWPDESRIMGFELHHGESTPTNSQKVKVKDLCNETSLGWVNEECNPIKAAGTYLHGIFDNGTWRRLWINQIRKKANLYELPLLEENHDAKREKVINRLTDVFEENINLEYLLKT
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: SYR_AQUAE
Sequence: MKELVKEKVLKALKELYNTQVENFKVEKPKEEAHGDLASNVAFLLARELKKPPVNIAQELADFLSKDETFKSVEAVKGFINFRFSEDFLKEEFKKFLLSGEAYFKEDLGKGLKVQLEYVSANPTGPLHLGHGRGAVVGDTLARLFKFFNYDVTREYYINDAGRQVYLLGISIYYRYLEKCPERDEETFKEIKEIFEKDGYRGEYVKEIAERLRKLVGESLCKPEEANLKEVREKILKEESIELYYTKKYEPKDVVDLLSNYGLDLMMKEIREDLSLMDISFDVWFSERSLYDSGEVERLINLLKEKGYVYEKDGALWLKTSLFGDDKDRVVKRSDGTYTYFASDIAYHYNKFKRGFEKVINVWGADHHGYIPRVKAALKMLEIPEDWLEILLVQMVKLFREGKEVKMSKRAGTFVTLRELLDEVGKDAVRFIFLTKRSDTPLDFDVEKAKEKSSENPVYYVQYAHARISGIFREFKERYKKDVSVEELINYVQHLEEEAEIKLIKKVLFFKDELVDITLKREPHLLTYYLIDLAGDFHHYYNHHRILGMEENVMFSRLALVKGIKEVVRLGLNLMGVSAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_MYCTO
Sequence: MSRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDGDSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSIVVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLADVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEAVR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_MYCMM
Sequence: MLLAIDVRNTHTVVGLLSGAKQHAKVVQQWRIRTESEVTADELALTIDGLIGEDSERLTGATGLSTVPSVLHEVRIMLEQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAYQQFAKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAGLVDGLVARIREDVKGFSADDDVAVVATGHTAPLLLPELHSVEHFDEHLTLHGLRLVFERNREAQRGRLKPAR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAZ1_HUMAN
Sequence: MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
What is the function of this protein?
RNA-binding protein that plays an essential role in spermatogenesis.  May act by binding to the 3'-UTR of mRNAs and regulating their translation.  Promotes germ-cell progression to meiosis and formation of haploid germ cells.
What are the official names of this protein?
Deleted in azoospermia protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM DAZ family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
Protein: ATPE_NEIMB
Sequence: MSIMQVEVVSSEQKIYSGEATFIVVPTVQGELGIYPRHEPIMSLVRPGALRLTVPGEDKEVLVAVSGGVLEVQPDKVTVLADVAVRSAEMDRARAEEAKKAAEAGISQAKDDKALAEAHKVLAAAIAQLKTLDYIRSHKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PR99C_DROME
Sequence: MGRKRGRKEYCPPIYKRQKVARVTNNGYLNFMTEYKKRFYGLSPQDMVHYAAKQWTQLSMAEKEAFKSKKPSTITLKSPAQYVACEMKSDVAGGQQSSCQRQSPSARLRESERRSSRSKTLCRSAKNRQRGKPKPQQSKRRLSHMGSAVAYIHFLRKFQRKNTELRTIDLLKTATRLWCRLPERHRHAFERPLWIVTIGKS
What is the function of this protein?
Regulates chromatin compaction in spermatid nuclei and is essential for male fertility.  Functions in parallel with other chromatin-condensing proteins such as ProtA, ProtB and Mst77F.
What are the official names of this protein?
Protamine-like protein 99C.
What is the protein family that this protein belongs to?
Belongs to the UPF0771 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Expressed in mature sperm chromatin.
Protein: TRPC_BRUA1
Sequence: MSTDILRKIEAYKREEIAAAKARLALDELKARTRDQSAPRGFLKALEAKRAAGQFALIAEIKKASPSKGLIRPDFDPPALAKAYEEGGAACLSVLTDTPSFQGAPEFLTAARQACSLPALRKDFLFDPYQVYEARSWGADCILIIMASVDDDLAKELEDTAFALGMDALIEVHDEAEMERALKLSSRLLGVNNRNLRSFEVNLAVSERLAKMAPSDRLLVGESGIFTHEDCLRLEKSGIGTFLIGESLMRQHDVAAATRALLTGAEKL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: SYGA_HELPG
Sequence: MQDFSSLLLKLQEYWKNQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQVVIKPSPSNIQELYLKSLEVLGINLNEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIACSPIPVEITYGLERLAMYVQKVENILEIEWAKNNHDSVRYAQVHLESEYQFSKYHFEVASVTRLLEMFKNAQAEALHCLKNKLPLPAYDLVMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCTILYKEQEEEREERLKNALTKA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTBP1_RAT
Sequence: MSGVRPPIMNGPMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGAAYSRYPPGVVSVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHTTDQL
What is the function of this protein?
Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6.  Has dehydrogenase activity.  Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex.  Functions in brown adipose tissue (BAT) differentiation.
What are the official names of this protein?
C-terminal-binding protein 1, CtBP1, 50 kDa BFA-dependent ADP-ribosylation substrate, BARS-50, C-terminal-binding protein 3, CtBP3.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Synapse, synaptosome.
Protein: PROB_SHIFL
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRRNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_LEUMM
Sequence: MTLAKRIVPALDIKNGRVVKGVNFVNLREVGDPVESAKAYQAAGADELVFLDITATLEERDTIMSVVDAVSREVFIPLTVGGGIRTTEDMGRLIKAGADKIFVNSEAVKNPALITDGAKIFGSQAIVGAIDAKWDESAGIYRVYVSGGSKPTSLDAIEWAFELVARGAGELLVTSMDADGTKKGYDIQLYDQLADAVNVPVVASGGAGSTQDFVNLFEKTKIDAALAASVFHFGEIKIPNLKRTLKDDGVEIRI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4A_YEAST
Sequence: MARGPKKHLKRLAAPHHWLLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNRLKYALNGREVKAILMQRHVKVDGKVRTDTTYPAGFMDVITLDATNENFRLVYDVKGRFAVHRITDEEASYKLGKVKKVQLGKKGVPYVVTHDGRTIRYPDPNIKVNDTVKIDLASGKITDFIKFDAGKLVYVTGGRNLGRIGTIVHKERHDGGFDLVHIKDSLDNTFVTRLNNVFVIGEQGKPYISLPKGKGIKLSIAEERDRRRAQQGL
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S4-A, RP5, S7, Small ribosomal subunit protein eS4-A, YS6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMEDA_YEAST
Sequence: MQVLQLWLTTLISLVVAVQGLHFDIAASTDPEQVCIRDFVTEGQLVVADIHSDGSVGDGQKLNLFVRDSVGNEYRRKRDFAGDVRVAFTAPSSTAFDVCFENQAQYRGRSLSRAIELDIESGAEARDWNKISANEKLKPIEVELRRVEEITDEIVDELTYLKNREERLRDTNESTNRRVRNFSILVIIVLSSLGVWQVNYLKNYFKTKHII
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.  Possesses a C-terminal dilysine motif that interacts with COPI coat subunits.  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum.
What are the official names of this protein?
Endoplasmic reticulum vesicle protein 25.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Protein: FENR_EHRCR
Sequence: MTDYVTDIAVIGAGPVGIFTVFQAGMLKMRCCVIDALSEIGGQCLALYPEKPIYDIPGYPVINGKELIDSLKKQSEPFNPQYLLGQVAEKIEDYSDYFLIRTTTGIVVQSKVIIIAAGAGAFGPNRLPIDNILDYENKSVFYQVRKVSDFCDKNIMIAGGGDSAADWAVELSKVAKQLYVVHRRKNFRCAPNTALQMDNLSQSGKIKIIVPYQVKKLCGENGKLHSVIVKNITNHEEMALQVDYLFPFFGTSANLGPILNWGMEVKNYQILVNAETCLTNRNRIYAVGDIATYPGKLKLILTGFSEAAMACHHIYHVIYPNSPLNFQYSTSKGIPENC
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: LAC1_YEAS7
Sequence: MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDSGLAFFSFAIFVVAWIYLRHYINLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILKDDRSDSESDEESDESSTTPTDSTPTKKDI
What is the function of this protein?
Component of the ceramide synthase complex required for C26-CoA-dependent ceramide synthesis.  Redundant with LAG1.  Facilitates ER-to-Golgi transport of GPI-anchored proteins (By similarity).
What are the official names of this protein?
Sphingosine N-acyltransferase LAC1.
What is the protein family that this protein belongs to?
Belongs to the sphingosine N-acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ZNUC_WOLPM
Sequence: MSHINVEKKLNFVNKLNNVNNRVLKIENLALAYDGKRILDNINMFMERGDIITILGPNGGGKTSLVKAIAGINKNYTGNIVLAENTKISYMPQNFSISNLMPITVEYFLLNSSFKRLKKNQSIITETIELAGIGNILKNQVLEISAGQTQLLLLARCLIAEPDLIILDEPVSAMDINARAKFYDIINKIAKKRLVSILMTSHDLNSALPSSDYIICINNTIYCQGKPDEIMKNRTLNEIFSSYAAK
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GGN5_GLARU
Sequence: MFTLKKSLLLLFFLGTISLSLCEEERNADEEEKRDVEVEKRFLGALFKVASKVLPSVFCAITKKC
What is the function of this protein?
Has a non-hemolytic activity.  Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.
What are the official names of this protein?
Gaegurin-5.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UREG_STAAN
Sequence: MANPIKIGIGGPVGAGKTQLIEKVVKRLSKEMSIGVITNDIYTKEDEKILVNSGVLPESRIIGVETGGCPHTAIREDASMNFAAIDELLERHDDIELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASLEQMAEDTKVFRGKRPFTFTNLKTDEGLDEVIDWIERDTLLKGLS
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.