PharMolix/UniProtQA huggingface dataset:
Protein: PLSX_THEP3
Sequence: MRLAIDAMGGDHAPEEIIKGSLEALKHFQDIEIVLIGKEEVLRGLQRKEKRLKLVYASEVIENDEAPVTAVRKKKDSSMIVGLELLKKEEVDAFLSAGNTGALMAGALLTLGRIKGIDRPALAPILPTLNGATVLLDAGSNTNCDAQNLVQFAVMGHVYAQKMFEIERPRVGLFNIGAEEEKGNEVVKKAFEELKKSKLNFIGNVEGRDIPYGVCEVVVCDGFVGNAILKSMEGIASVISQLLKEELTRNIFTKLGALLIMGGLKRITKKMDYTEYGGAPLLGIKKPVIKAHGNSKAKAIFNAIKQAKNFVDNDVLNHIKEEIESMGDELSV
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RS16_POLAQ
Sequence: MVVIRLARGGSKKRPFYSIVATDKRNRRDSNFIERIGYFNPQAAATEQAMRIAQDRLTYWTGVGAQISPTVVRLIKNNPAV
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TM117_HUMAN
Sequence: MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRILKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKSSHLTSENLSSQLNESTSATEADQDPTTSKSTPTN
What is the function of this protein?
Involved in endoplasmic reticulum (ER) stress-induced cell death pathway.
What are the official names of this protein?
Transmembrane protein 117.
What is the protein family that this protein belongs to?
Belongs to the TMEM117 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: F16PA_YERPB
Sequence: MKTLGEFIVEKQLDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGVSNIQGEDQMKLDLFANEKLKAALKARGEVAGIASEEEDDIVIFDGGRAENAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPFGTPITEEDFLQPGTKQVAAGYVVYGSSTMLVYTTGYGVHAFTYDPSLGVFCLSHEKVRYPATGCMYSINEGNYIKFPLGVKKYIKYCQEQDEATKRPYTSRYIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKATDGVNRILDIVPEKLHQRAPFFVGTKSMVEDAEGFIAKFPDEEAK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_BACAA
Sequence: MKIVKISPRGYCYGVVDAMVIARNAALDTSLPRPIYILGMIVHNKHVTDAFEEDGIITLDGPSRLDILDKIDSGTVIFTAHGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEGYHVIYIGKKNHPEPEGAVGIAPDIVHLIERADDLKTLEIPTDKILVTNQTTMSQWDVQHLMEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIAGTKAYRVADVSEIKLEWLQGVENVAVTAGASTPTPITKEVIAFLEQYDPMNPATWERVRKVPLQKILPRVKVKKEQ
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: FABZ_BRUSU
Sequence: MSDDNQTKLEAADIQALLAVLPHRYPFLLIDRIVDIDGDVSATGIKNVTINEPHFTGHFPENPIMPGVLIVEAMAQTAGAISLLQRKTGRPGVVYFMTIDNAKFRRPVVPGDRLLLHVKKIKQRANISKYECVAEVDGVKVAEAEVAAMISVADENL
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_TAMVU
Sequence: MSDQSVPSFRWVQSLKRGLSVWTTPVKADVLNDTRALLSGLDFSKVASVQRMMRRERRDDNDLTNLRDNLKEVDSLMTMRSSQKNMFLKVGSLSKDELMELSSDLNKLKEKVQRSERIIGGSGVYQGNFTTTHLTRRSEILQLVGIQRPGLNRRGGVVKIWDIKEPALLINQFGSTPAVTISCMAEQGGETLNDVVQGLTDLGLLYTAKFPNLGDLEALSNKHSCLKVITQEESQINISGFNLSLSAAVKAGACLVDGGNMLETIKVEESTFTTIIKTLLEIKSKERMFVDITPGQRNPYENLLYKLCLSGEGWPYIASRSQIKGRAWDNTVIEFDVSPRKPPVPIRNGGSPVLTTLKPEVEEQIKRSIESLSVHDTTWIDIEGPPFDPVEMAIYQPDSLKYIHCYRKPNDVKSFKDQSKYCHGILLKDIEFARPGIISAIIKHLPKSMVFTAQGSEDIRRLFDMHGRQDLKIVDVKFTAEQSRVFEELTWKRFEHLCDKHKGIVIKSKKKGTTPASTNAHCALMDCIMFSGVLLGAIPNDKPRRLLPLDILFREPDTTVVL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RL5_BACC7
Sequence: MNRLKEKFQKEITPALMSKFNYKSVMQVPKIEKIVINTGVGDAVSNSKALDNAVEELTQIAGQKPVVTRAKKSIAGFRLREGMPIGAKVTLRGEQMYEFFDKLVSVSLPRVRDFRGVSKKSFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEARELLTQFGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: G1P_BPPHL
Sequence: MLVFNEGVPRAGKSYDAVKNHILPALKKGRRVFARLNGLRFDRIAKHLGMAENDVQHLLVLVDTKDVSKLFACTQDESGKWCIPDEFKDALVVIDEVHEFYVNERKPLAPAVENFWALLGQNGGDAVIMTQWINRLHSAVKARIEKKNTFQKLTAIGMKGRYRVTYFHTTSPGKFEKVGGQTLKYDPAIFPLYDGYAPGAENTEVYEEGGKNVWAAMAVRAAIFLTLGGVGIYFFMHYFTKDRADPNKPMASASQTTKPTHVGAGFANGAPSVPIQPPPPDPLADLTQEQRYVAQLADKGRIRLSARARVGDQDRAWIQWIDASNNVVEELDLSQLRALGYSVSVVTYGVRLSAGKHIMVATAWPWTAPIREKDARLYNMAPDGSGGAAGVATAGSDGGGADRDQVRGGVIEYGPRTQGTFPDNKGYSSSTSTPATTLQM
What is the function of this protein?
Isoform G11P is also involved in phage assembly, probably playing a structural role in the formation of the phage assembly site.
What are the official names of this protein?
Gene 1 protein, G1P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G1P protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: EFTS_METNO
Sequence: MANITAAMVKDLREKTGAGMMDCKSALNETAGDIEAAVDWLRKKGLAKAAKKAGRVAAEGLVAVESAGRHAAVVEVNSETDFVARNDSFQAFVREAAKVALNAEGGVEALEAAHFPGSQTTVKDRLQELIATIGENMTLRRTAKLTVEKGVIATYVHSQVSEGLGKIGVLVALESDGDVGFLSTLGRQIAMHVAATNPLALDATGIDQATIERESNILREKNAGKPDHVLAKIVESGLKSYYKEVTLLEQPFVHDTSKTVSQVLKEAEGKAGGPVKLAGFVRYALGEGIEKEEGPDFASEVAAAAKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXO84_EMENI
Sequence: MDGRGLTLRSKNRRPRPQISAPKPISGPLPQNHQPAASGSGTASSGSGSRDYASSNHATSDLVKRRYSTRFNQVPDFDGAPPVPSVPQVPSAYAGLGPPQPSRKQSAESSGPPEVDLTALRDPSLPVDRYVTNLLANASEDDIREYQQALRKVKNRTSTDLQQNVYQNRTQFIRISQEADKLKGEMKTLRSLMAELTTALGQTAIGDSPNPMSPTLDERASKRSNRSSVANLESMWNVQLQTLWKTVEGSQKFLPMVPGRHIVLETGNWAELDSATWKPRRPVHLVLLNDHLLVAAKKRKRVDQSNPNHRGPVPTKLIAEECWPLQDIDMIDLGANLTGSAREEAEDRGITNAVCVRVGSKPFTYRHDKRNSTAKSELLATFRKTVEDLRRTLRSETEAAGKNGESLGFMSAINSRNSLLCSPKLDLSENTDNPRDRPEVRIDVDGKQQNLRWVDSQVDELDIDIALQRFEEAVSNIDRLRKLARGLKGNAVAQDVINTKVDERAAKLAGILSRSLVDTHGFPVATKTNVVWLTRLGFEDQARESYLKARSDVISKRIRTYQQCFPSVMTSACIKWAKHHLDAFNALLTRQLSSVQRGATVWQNCINIVHEQAGILAEVGVDFTDLVAKELELTEEEKAARPEMTRSESLIMGLADAASFFNMYGH
What is the function of this protein?
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis.  Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis.  Also involved in assembly of the spliceosome (By similarity).
What are the official names of this protein?
Exocyst complex component exo84.
What is the protein family that this protein belongs to?
Belongs to the EXO84 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Cell periphery. The polarization of EXO84 requires actin cables (By similarity).
Protein: Y3026_RHOE4
Sequence: MTTDSAKDSRTMDFLLVTGLSGAGLSTAAKVLEDLGWYVADNLPPELISRMVGLSLTSDPPVDRLAVVIDVRSRLFTGDLGWVLTELEAEPIHTRVLYLEASDDVLIRRFEQVRRSHPLQNDGIDGTLSEGIAAERRQLAVVKAAADLVIDTSALKAHQLRQKIETAFGNDANRTMKVTVQSFGFKYGLPMDADLVCDVRFLPNPHWIPELRPHTGQDADVRDYVLSREGAEDYLDTYRHLVDLTIAGYRREGKRYMTIAVGCTGGKHRSVAMSEALARRLGSEDDISVSIVHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein RER_30260.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: DNAT_ECOBW
Sequence: MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPKRDVNTVSEPDSQIPPGFRG
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: MNME_BURMA
Sequence: MLATDSDPIVAIATASGRGGIGVVRLSLGRAGEAAARALSDALCGARLMPRHASYVPFLDGAGEPLDRGIALYFPAPHSYTGEHVIELQGHGGPIVLQLLLQRCLDAGRAHGLRLAEPGEFTRRAFLNDKLDLAQAEAVADLIEASTEAAARSAGRSLDGAFSRDIHALVDDVIALRMLVEATLDFPEEEIDFLEAADARGKLAHIRERLAHVLGDARQGALLREGLSVVLAGQPNVGKSSLLNALAGAELAIVTPIAGTTRDKVAQTIQIEGIPLHIIDTAGLRETEDEVEKIGIARTWGEIERADVVLHLLDARSGLGPGDEAIAARFPDGVPVVRVLNKTDLTGAPASVTRTGGGAARADVCEVRLSAKRGDGIDLLRGELLRIAGWQAGAESVYLARERHLIALRAAQAHLARAAEHAEQNAQALDLFAEELRLAQERLNSITGEFTSDDLLGVIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTM_PISOC
Sequence: MCDEDVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVFDTGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYTALDFEQEMQTASSSSSLEKSYELPDGQVITIGNERFRCPETLFQPAFIGMESAGIHETTYNSIMKCDIDIRKDLYANTVLSGGTSMYPGIADRMQKEIQALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, muscle.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RAS1_DROER
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLASWNVNNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKDKDNKGRRGRKMNKPNRRFKCKML
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.  Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells.  During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: MTLD_ECO55
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYSLPHKNLIQGIAGAMHFRSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: IMSP6_RUDPH
Sequence: MKLEIALLLLAVTVCVKGGFLQGRSGYDCRRRCGYDRRYVCSTDGTTYDNECMMKCNWAYKSCDGRCPCYRSPAPVVYRPKPAVVYKPRPVVNYEPASVNYEPASVNYEPAAVDYPSVPDYEPIPVYNEPAPVYYDVPVQSDCVCSKDKDYVCTYDGETYDNECEANCDGKAKMCDGQCPCSK
What are the official names of this protein?
Insoluble matrix shell protein 6, IMSP6.
Protein: YC12A_PYRHO
Sequence: MRKGTVKEVLAKIKYDPRENENDYYLIIEHRGDYGNVKKIPVNLIELGHGYFFVGETQIPYHRILKVVRKDGRVIWESRKIRK
What are the official names of this protein?
UPF0248 protein PH1212.1.
What is the protein family that this protein belongs to?
Belongs to the UPF0248 family.
Protein: SYS_COXB1
Sequence: MLDPKILRQNLEHVVEKLRRRGFEMDSDTFLQLENKRKEAQLAIQSFQTKRNQLSKTIGMAKSKGENPEPLMAEVSQLNDELKQEEANFETIQKAFSDFQLAIPNLPHDSVPDGKSENDNREIRQWGAPPGFDFTPKDHTVLGERDNQLDFEAAAKLSGARFVVLRGSLARAHRALAQFMLDLHTDQHGYEEVYVPYLVHEECLYGTGQLPKFREEQFQVAGDRNFFLVPTGEVPLVNLARDEIIEAPALPKKWVAQTPCFRSEAGSYGKDVRGMIRQHQFQKVELVQLVQPENSYQTLEEITRQAEKVLQLLALPYRVVELCAGDLGFAAAKTYDLEVWLPSQNKYREISSCSNCEDFQARRIQARWRNPKTGKPELLHTLNGSGLAVGRTLVAVMENYQQADGHIRVPDALKSYMGGVDYF
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_ARCFU
Sequence: MLAKRIIPCLDVTLDESEARVVKGVEFVNLRDAGDPVELAKRYDEEGADELVFLDITASPEGRRTMIDVIERTAEQVFIPFTVGGGIKSIEDINTILSAGADKVSINTAAVKNPEFVREAADIFGSQCIVVAIDCRRNFDLSKGEYIVELEDGTKAWYEVVIYGGRKPVGIDAVWWAKRVEELGAGEILLTSMNRDGTKDGFDIPITRKISEEVNIPVIASGGAGTKEHFYEGFVEGKADACLAASIFHYREIGIREIKEYLAERGVQVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCNNG_HUMAN
Sequence: MAPGEKIKAKIKKNLPVTGPQAPTIKELMRWYCLNTNTHGCRRIVVSRGRLRRLLWIGFTLTAVALILWQCALLVFSFYTVSVSIKVHFRKLDFPAVTICNINPYKYSTVRHLLADLEQETREALKSLYGFPESRKRREAESWNSVSEGKQPRFSHRIPLLIFDQDEKGKARDFFTGRKRKVGGSIIHKASNVMHIESKQVVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGVSCDARNFTLFHHPMHGNCYTFNNRENETILSTSMGGSEYGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMVTSIGMHLTESFKLSEPYSQCTEDGSDVPIRNIYNAAYSLQICLHSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLHRAFVQEELGCQSVCKEACSFKEWTLTTSLAQWPSVVSEKWLLPVLTWDQGRQVNKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDLPTFNSALHLPPALGTQVPGTPPPKYNTLRLERAFSNQLTDTQMLDEL
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride.  Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells.  Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.  Controls the reabsorption of sodium in kidney, colon, lung and sweat glands.  Also plays a role in taste perception.
What are the official names of this protein?
Amiloride-sensitive sodium channel subunit gamma, Epithelial Na(+) channel subunit gamma, ENaCG, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells.
Protein: IHFA_HAES1
Sequence: MALTKIELKNSLIEQGLNKLEAKKVVEGFFEQIRVSLENGEDVKLSGFGNFELRDKSSRPGRNPKTGEAIPVSARRVVVFRPGQKLRSRVEKTKPKN
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: DHX15_PONAB
Sequence: MSKRHRLDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNAMLISAGLPPLKASHSAHSTHSAHSAHSTHSAHSTHAGHAGHTSLPQCINPFTNLPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRIIAKLQSKEYSQY
What is the function of this protein?
RNA helicase involved in mRNA processing and antiviral innate immunity.  Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.  In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns.  Plays a key role in antiviral innate immunity by promoting both MAVS-dependent signaling and NLRP6 inflammasome.  Acts as an RNA virus sensor: recognizes and binds viral double stranded RNA (dsRNA) and activates the MAVS-dependent signaling to produce interferon-beta and interferon lambda-3 (IFNL3).  Involved in intestinal antiviral innate immunity together with NLRP6: recognizes and binds viral dsRNA and promotes activation of the NLRP6 inflammasome in intestinal epithelial cells to restrict infection by enteric viruses.  The NLRP6 inflammasome acts by promoting maturation and secretion of IL18 in the extracellular milieu (By similarity).  Also involved in antibacterial innate immunity by promoting Wnt-induced antimicrobial protein expression in Paneth cells (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DHX15, DEAH box protein 15.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: GN_SUHVK
Sequence: MVSSAGLSLTLVAALCALVAPALSSIVSTEGPLPLLREESRINFWNAACAARGVPVDQPTAAAVTFYICLLAVLVVALGYATRTCTRMLHASPAGRRV
What is the function of this protein?
Envelope glycoprotein necessary for proper maturation of gM and modulation of its membrane fusion activity.  Also plays a critical role in virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein N.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein N family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host membrane; Single-pass type I membrane protein. Host Golgi apparatus, host trans-Golgi network. Note=When coexpressed with gM, localizes in the host trans-Golgi network.
Protein: KCY_PSE14
Sequence: MKIKAPVITIDGPSGSGKGTVAGLLARKLGWCLLDSGALYRLLAFAARNHGVDLTNEEALKLLAAHLDVQFEATAAGQGQRIILEGEDVTHAIRNEQVGSGASQVASLPAVRDALLLRQRAFQEEPGLVADGRDMGTVVFPDAPLKIFLTASAEERARRRYLQLKAKGDDVSLSSLLDEICARDERDTQRAVAPLKPAHDAIQLDSTELSIEQVLERILSEIALRGIAG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2228_XYLFA
Sequence: MSMPTMTLVNQLLIALPSMPDPHFARGVALICQHDSNGSMGVVLNRPSEYTLGEVLFQMGIETASETLREQVVLAGGPVHPDRGFVIYDSEHVWGPSLLIGDGLYLTTSRDVLTAMAEGSGPSRALVALGCAGWAAGQLELELVENNWLMVPADASLLFDTALEQRWQRAAGRIGVDLFRLTDYTGHA
What are the official names of this protein?
UPF0301 protein XF_2228.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.