PharMolix/UniProtQA huggingface dataset:
Protein: ARS_HEMPU
Sequence: MKSAPFLFLLGLLGLVTAQTQDPALLDLLRENPDLLSLLLQSNEHRAPLVKPNVVLLVADHMGSGDLTSYGHPTQEAGFIDKMAAEGLRFTNGYVGDAVCTPSRSAIMTGRLPVRIGTFGETRVFLPWTKTGLPKSELTIAEAMKEAGYATGMVGKWHLGINENSSTDGAHLPFNHGFDFVGHNLPFTNSWSCDDTGLHKDFPDSQRCYLYVNATLVSQPYQHKGLTQLFTDDALGFIEDNHADPFFLYVAFAHMHTSLFSSDDFSCTSRRGRYGDNLLEMHDAVQKIVDKLEENNISENTIIFFISDHGPHREYCEEGGDASIFRGGKSHSWEGGHRIPYIVYWPGTISPGISNEIVTSMDIIATAADLGGTTLPTDRIYDGKSIKDVLLEGSASPHSSFFYYCKDNLMAVRVGKYKAHFRTQRVRSQDEYGLECAGGFPLEDYFDCNDCEGDCVTEHDPPLLFDLHRDPGEAYPLEACGHEDVFLTVKSTVEEHKAALVKGTPLLDSFDHSIVPCCNPANGCICNYVHEPGMPECYQDQVATAARHYRP
What is the function of this protein?
May be a structural component of the extracellular matrices involved in cell movement during morphogenesis.
What are the official names of this protein?
Arylsulfatase, AS, Aryl-sulfate sulphohydrolase, ARS.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted, extracellular space, extracellular matrix.
Protein: Y363_CHLTA
Sequence: MGSGYAKKKKEAKLMERQFMEMEASLEQKRFSGEAGNGLVSVTINGKCDLVDVRIKPDCLDPEDPEVVADLFRAAFKAAKAALDSEMSAMQMGMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CTA_0363.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RRF2M_KLULA
Sequence: MQHTMSFRIFLRRYATKHDLSKVRNIGIIAHIDAGKTTTTERMLYYSGKINRIGDVDQGDTITDYLPQERSRGITIQSAAISFNWKKDYKINLIDTPGHADFTFEVIRSLKVLDSCVTILDSVAGVEAQTEKVWKQSSGLPKICFLNKMDRVGAGFSRTVKELVVKMNTRALLINTPIFQVDPVTNESKFSGVLDLIYGKQLIWDTNDPDKINVTDVDENHDCYEYLVRGREALVETLGETDESIVEHFFNDADGEYLNVSPEVLNASIRKATISLSATPVLCGASFRNIGVQPLLDAIANYLPSPSEARPPELNHKNVPITQNPLTGLVLNKNPNLCVALAFKVITDAIRGTMIFIRVYSGVLRSNHTVYNTTTGTKFKIGKLVRMHANVPEEVNELYPGDIGVLTGSNVSEHIRTGDTIVTHVTKKDGLRSFDKNVELTLKINPIEIPPPVFNAAIEPKTLGNKKPMEQALSQLTREDPSLVVTHDEETGQTLLSGMGELHLDIARDRLLNELNAQVDVERVIVSYKETLNHSTQEKTLETDDGYKITAVIEPLDEEMKAKAKKDEEWFSLANDNNFMIMEKHTKYDPDKNWPFQVPYVAVVNALLPSSLVALQRGGKIGGFPLSSCVIRIKNDWDLPIDAPSISPLLTLSRQLFTQILLGEDQSNYSVLEPVMNVDVTVQQQDMGPVIQDLSSARKANILSIEDENTNTVSESNIRFQHIADKMWLPEDPTLEFAKLGKEGQAPKMVKAQAPLKEMVAYNNKIRSITQGRGSFNMYYHGMQPVTHDRLQSVLADYHQ
What is the function of this protein?
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.  Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
What are the official names of this protein?
Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NOP58_ASHGO
Sequence: MAYVLTETAAGYALLKASDKKIYKSSSLVQDLKSSENVLKQFKVAAFSKFASAANALEEANSVIEGKVSSQLEKLLAEAKSDKKSTLVVSETKLANAINKLGLNFNVVCDAVTLDIYRAVKEYLPELLPGMTDGDLSKMSLGLAHSIGRHKLKFSADKVDVMIIQAIALLDDLDKELNTYAMRCKEWYGWHFPELAKIVTDSVAFARIILTMGVRSNAAETDMSEILPEEIEERVKSAAEVSMGTEITQVDLDNIKSLAEQIVEFAAYREQLSNYLSSRMKAIAPNLTQLVGELVGARLIAHAGSLVSLAKAPASTIQILGAEKALFRALKTKHDTPKYGLLYHASLVGQATGKNKGKIARVLAAKAAVSLRYDALAEDRDDSGDIGLEARAKVESRLSQLEGRDLRTTPKVSRDAKKIEISEARAYNADADAATAPADSTPADSDDEEEEEKKVKKDKKDKKRKREEDAEEEDSKKSKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKK
What is the function of this protein?
Required for pre-18S rRNA processing.  May bind microtubules (By similarity).
What are the official names of this protein?
Nucleolar protein 58.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL24_AQUAE
Sequence: MAAAKIKKGDTVLVVRGKEKGKQGKVLKVYERVKRRDKQGNPVYVRHFVIVEGVRLIKKHVKPIEGVREGGIIETEGPIDISNVMLICPNCNKPTRVGFRIVEEGNVRRKYRYCKKCNENIDLVSEKVIKGG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: AL4A1_DANRE
Sequence: MLRARSAVSQSWKGFKTFSCVAVEVKNEPVLEFKEGSKERAELEEALRNLKGKTEEIPCVIGNEEVWTKDIRFQLSPFNHSHQVAKFCYADKDLLNKAIEASVAARREWDLKPVSDRAQIFFKAADIISGPKRAEVLAKTMIGQGKTVVQAEIDAAPELIDFFRFNAKHAIELEDQQPLDSDGSTNTMLYRGLEGFVAAVAPFNFTAIGGNLAGTPALMGNVVLWKPSDTAMSASYAVYKILRESGLPPNIIQFVPADGPVFGDTVTSSEHLAGINFTGSVPTFKRLWKQVAQNLDIYKNFPRVAGECGGKNFHFVHKSADVRSVVTGTIRSAFEYGGQKCSACSRMYVPDSLWPQIRQGLLDVYKQIKVGDPVEDFSTFFSAVIDDKSFSRIKGWLEHARSSPHLKIIAGGNCDDKKGYFVEPTIIETTDPQEKIMNEEIFGPVLTVYVYPENDYKKVLHLIDNTSPYALTGAIFPQDKSVIEEAGKALRNAAGNYYINDKSTGSIVAQQPFGGARASGTNDKPGGPHYVLRWTSPQVVKQTHVPLTEWKYPYMS
What is the function of this protein?
Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate.  This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity).
What are the official names of this protein?
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, P5C dehydrogenase, Aldehyde dehydrogenase family 4 member A1, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: UVRB_CLOBL
Sequence: MNQFKVISKFNPTGDQPKAIKSIAKGIEKREKFQTLIGVTGSGKTFTMANIIEKVQKPTLVLAHNKTLAAQLCSEFREFFPNNAVEYFVSYYDYYQPEAYVAQSDTYIEKDASINDEIDKLRHSATSALFERKDVIIVASVSCIYGLGNPEEYKKLTISLREGMEKDRDEIIKKLVEIQYERNDIDFSRGTFRVKGDVLDIFPASSSSKAVRVEFFGDEIDRIKEFDVLTGETITKLKHISIFPASHFATSKDRLEVAIKDIEEELEERVKELVSQDKILEAQRLKQRTNFDIEMMREVGYCTGIENYSRVLDGRAKGTPPQTLLDYFPQDFLLFIDESHVTLPQVKAMQAGDKSRKDSLVEYGFRLPCAYDNRPLTFKEFENKLNQVVFVSATPAKYELEYSTNTAEQVIRPTGLLDPEIIVKPVKGQIDDLYTSIQETIKRGFRILVTTLTKKMAEDLTDYLKEMGVKTRYLHSDIDTIERMKIIHDLRKGEFHVLVGINLLREGLDIPEVALVTILDADKEGFLRSETSLIQTVGRAARNSESKVIMYGDVITKSMEKTIKETNRRRKIQMEYNEEHGIVPKTIIKDIREVIQISDIAEERKEYDNLNEALKSYNNDIDKLIEKYEEEMKEAAQNLQFEKAAHLRDVIYKLKKDKETEL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG172_MONPV
Sequence: MMMKWIISILTMSIMPVLTYSSSIFRFHSEDIELCYGNLYFDRIYNNVVNIKYIPEHIPYRYNFINRTFSVDELDDNVFFTHGYFLKHKYGCSLNPSLIVSLSGNLKYNDIQCSVNVSCLIKNLATSTSTILTSKHKTYSLYRSMCIAIIGYDSIIWYKYINDRYNDIYDFTAICMLIASTLIVIIYVFKKIKMNS
What are the official names of this protein?
Protein OPG172.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG172 protein family.
Protein: GPMA_LISMF
Sequence: MKLVLIRHGQSEWNKLNLFTGWHDVDLSQEGVVEAMTAGKRIKEAGLEFDVAFTSVLTRAIKTLNYVLEESDQMWVPVHKSWRLNERHYGALQGLNKQETAEKYGADQVQKWRRSYDTLPPLLEENDERQAKNDRRYQLLDTHAIPAGENLKVTLERVIPYWMDTIAPEIKEGRRVVIAAHGNSLRALVKFLEGIGDDEIMDLEIPTGVPLVYELNDDLKPVNKYYLDK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: AROC_CROS5
Sequence: MGNTFGHLFRITTFGESHGGGVGVIIDGCPPRLDLSESDIQGDLDRRRPGQSKITTPRKETDTCEIISGVFQGKTLGTPIAILVRNKDARSQDYNEMSVKFRPSHADATYEAKYGIRNWQGGGRSSARETIGRVAAGAIAKKILKQVANVEIVGYVKRIKDLEGNVNPDTVTLEEVESNIVRCPDADMAEKMIDLIDQTRRDKDSIGGVVECVARYVPRGLGEPVFDKLEADLAKAVMSLPASKGFEIGSGFAGTLLTGSEHNDEFYIDDNGNIRTKTNRSGGIQGGISNGEHIIIRVAFKPTATIGKEQKTVTSESEETTLAAKGRHDPCVLSRAVPMVEAMVALVLCDHLLRWQGQCQVLT
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SET6_CAEEL
Sequence: MERSRTGGSSTYSMSTANVPIITISDDDDELTIWEEPRKSPISSNSYSDERNHSLSSTSNSSVERSIIITISDDESEATERNQQEVVDRAISNNLTEKRRRSVESFHRLHSKERKLEVKSRKKSRTSSSSMEASTSCTFPARQTKTKRHKRKTYSTISSFAPHHSTICAELRNVNPARIADFRHPSIFEYSDMSLNERREHWKKEMKVIKKHNDIRLMHEEAVRFDDIIELDPTLNGYYRRFMGAEQSTRALFMAVRCLATFGRNFYEEPERDHGEEEIPEELDRYFEKLIYVAPRTRIRITDDIHLSNDTHRIPVYTDAKGETLKTVKIPNPLLYDHIINNMVDKVKEPLLYEAIKIAGSSENVIRCKCCSQDPVVNCFDNKDCPCFIANQFLQSRNKTTDTNEKLKFHTFQPLMYNDGNPTYYNTVGFACSPKCACKGACTNNATYLIQKKLYSIEIYRADPQIGFGIRSTLFIPAGTPIIEYCGELVDGERLHSSLENYSYQLTDCEGDKHLYNLLREKYKNNPEYYDVLDELSKHHFHLDAKMQGSVGRFANHSCTPNMEPLRLFKEGFTPANMRMIFFTLKDIFPGEPLTLDYGSEYKVFRRQRCLCRTFACRSGPHYEKFSNLDGKLIASCFVRLHHASRIRYSVDLQLIERFYSVGKVEEVRVDPCVSFSKYNLKWRRQLSTATCERLENVIEIELSDEDS
What is the function of this protein?
Histone methyltransferase that specifically di- and trimethylates 'Lys-9' of histone H3 (H3K9me2 and H3K9me3, respectively); involved in positively modulating the rate of age-related behavioral deterioration (PubMed:32103178).  May repress the expression of mitochondrial function-related genes by occupying their promoter regions, working in concert with probable chromatin reader protein, baz-2 (PubMed:32103178).  Involved in modulation of the mitochondrial unfolded protein response (UPR) (PubMed:32103178).  Regulates level of expression of bas-1, a serotonin (5-HT) and dopamine synthesizing enzyme (DOPA decarboxylase) (PubMed:32103178).  Negatively modulates levels of endogenous 5-HT and dopamine with aging (PubMed:32103178).  Involved in modulating longevity, probably as a result of enhanced stress resistance via mechanisms related to dietary restriction and mitochondrial function (PubMed:32103178).
What are the official names of this protein?
Histone-lysine N-methyltransferase set-6.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: AFS1_MALDO
Sequence: MEFRVHLQADNEQKIFQNQMKPEPEASYLINQRRSANYKPNIWKNDFLDQSLISKYDGDEYRKLSEKLIEEVKIYISAETMDLVAKLELIDSVRKLGLANLFEKEIKEALDSIAAIESDNLGTRDDLYGTALHFKILRQHGYKVSQDIFGRFMDEKGTLENHHFAHLKGMLELFEASNLGFEGEDILDEAKASLTLALRDSGHICYPDSNLSRDVVHSLELPSHRRVQWFDVKWQINAYEKDICRVNATLLELAKLNFNVVQAQLQKNLREASRWWANLGIADNLKFARDRLVECFACAVGVAFEPEHSSFRICLTKVINLVLIIDDVYDIYGSEEELKHFTNAVDRWDSRETEQLPECMKMCFQVLYNTTCEIAREIEEENGWNQVLPQLTKVWADFCKALLVEAEWYNKSHIPTLEEYLRNGCISSSVSVLLVHSFFSITHEGTKEMADFLHKNEDLLYNISLIVRLNNDLGTSAAEQERGDSPSSIVCYMREVNASEETARKNIKGMIDNAWKKVNGKCFTTNQVPFLSSFMNNATNMARVAHSLYKDGDGFGDQEKGPRTHILSLLFQPLVN
What is the function of this protein?
Sesquiterpene synthase catalyzing the production of (E,E)-alpha-farnesene, the predominant terpene produced during storage of fruits.  Produces all six isomers (E,E)-alpha-farnesene, (Z,E)-alpha-farnesene, (E,Z)-alpha-farnesene, (Z,Z)-alpha-farnesene, (E)-beta-farnesene and (Z)-beta-farnesene from a mix of isomeric forms of the farnesyl diphosphate precursor.  Able to convert geranyl diphosphate to the monoterpenes (E)-beta-ocimene, linalool and beta-myrcene.  Has also a prenyltransferase activity producing alpha-farnesene directly from geranyl diphosphate and isoprenyl diphosphate.
What are the official names of this protein?
(E,E)-alpha-farnesene synthase, MdASF1, Prenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_AZOVD
Sequence: MGNAFDGAAFLAHCSSHPGVYRMLDAKGELLYVGKAKNLRKRLSSYFRTSGLAPKTAALVARIAQVETTITANETEALLLEQTLIKEWRPPYNILLRDDKSYPYVFLSDGAFPRLGIHRGAKQRKGRYFGPYPSAGSIRESLGLLQKAFQVRQCEDSYFRNRTRPCLQHQIRRCKAPCVGLVEPAEYAEDVRHSVMFLEGRSNALAEELSAAMERAAVHLDFERAAELRDQIALLRRVQDQQSMEGGSGDVDVLAAVVKPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVGDVLAAFLGQYYLANPERDLPGEIIVNATHEDFPALVLALTEQRSRELHIRHRVRATRARWQQLAIANAEQALSARLAHRQHLAARFEALAEALDLDAPPLRMECFDISHSSGEATVASCVVFGPEGALKGEYRRYNIEGVTAGDDYAAMQQALTRRFGKLREGEGKLPDILLVDGGKGQLAIAQEVLRELAVPDLILLGVAKGVTRKPGLETLYLNDAVHEFTLPADSPALHLIQQIRDEAHRFAITGHRARRGKARRTSSLEEVAGVGPKRRRELLKFFGGLQELSRASIDEIAKAPGISKKLADSIYAALHSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARA_CALS4
Sequence: MKGYLKLEDGSIFEGELISKNKKGYGEVVFTTGMTGYQEAITDPSYAGQIVVMTYPLIGNYGINKYDFQSEKPHIRGFVVREYCDKPSNFQSEESLLSYLDNHNIPVLSGIDTRALTKKLRENGTMRGIITYNPEDNIEFDQTNLLEEVSTKKPYRIAGIGPKLAFIDLGTKKGILKMLNSVGFDIYVFPYNASYDDVMQINPDAIFLSNGPGDPKDAVDAIELTKHFIGMKPVLGICLGHQIIALALGCNTVKMKFGHRGANQPVKDLLTNKDYITSQNHGYAVEEESIDKDKITVTHINLNDGTVEGIMHKFLPVFSVQYHPEACPGPRDSTDIFDKFMDIVMVYKRRFYFAEV
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: RF1_BACCN
Sequence: MLDRLQAVEDRYEKLNELLSDPAVINDSNKLREYSKEQSDIQETVEVYREYKDVREQLQDAKAMLEDKLDAEMREMVKEEVSDLEVQEKELSDRLKILLVPKDPNDDKNVIVEIRGAAGGDEAALFAGDLYRMYSRYAEMQGWKTDIIEASYTELGGYKEIIFMINGKGAYAKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEAEEVEIDIHEKDIRVDTFASSGPGGQSVNTTMSAVRLTHLPTGVVVSCQDEKSQIKNKEKAMKVLRARIYDKFRQEAQAEYDQNRKQAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILQGKLDDFINALVMEDQAKKMEAAE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIRB2_BARHE
Sequence: MTDTISRNIIFIIIMLLLTALVVSDPSYAAAATGSASGLGNVDNVLQSIVTMMTGTTAKLIATICVAAVGIGWMYGFIDLRKAAYCLIGIGIVFGASALVSKLTSAS
What is the function of this protein?
The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function.  VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a pro-inflammatory activation by nuclear factor NF-kappa-B, inhibition of early and late events of apoptosis, leading to an increased cell survival, and, at high infection doses, a cytostatic or cytotoxic effect, which interfers with a potent VirB-independent mitogenic activity.  These changes of HEC require the T4S coupling protein VirD4 and at least one of the effector proteins BepA-G.  VirB2 seems to constitute the major pilus component.
What are the official names of this protein?
Type IV secretion system protein virB2.
What is the protein family that this protein belongs to?
Belongs to the virB2 family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: FIEF_YERPN
Sequence: MDPQYARWVKAAALSATALASILLIIKIFAWWHTGSVSLLAALVDSLVDLAASLTNLFVVRYSLQPADEEHTFGHGKAESLAALAQSMFISGSALFLFLTGFRHLASPEPLQDPSIGIGVTLVALFSTLILVTFQRWVVRKTHSQAIRADMLHYQSDVLMNGAILIALALSWYGFRRADALFALGIGVYILYSALRMGYEAVQSLLDRALPDDERQQIIDIVTSWPGVIGAHDLRTRRSGQTRFIQLHLEMEDMMPLMEAHVLAEQVEHALLYRFPGADVLIHQDPCSVVPKERHAHWEL
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTLY_BACLD
Sequence: MKKLISIIFIFVLGVVGSLTAAVSAEAASALNSGKVNPLADFSLKGFAALNGGTTGGEGGQTVTVTTGDQLIAALKNKNANTPLKIYVNGTITTSNTSASKIDVKDVSNVSIVGSGTKGELKGIGIKIWRANNIIIRNLKIHEVASGDKDAIGIEGPSKNIWVDHNELYHSLNVDKDYYDGLFDVKRDAEYITFSWNYVHDGWKSMLMGSSDSDNYNRTITFHHNWFENLNSRVPSFRFGEGHIYNNYFNKIIDSGINSRMGARIRIENNLFENAKDPIVSWYSSSPGYWHVSNNKFVNSRGSMPTTSTTTYNPPYSYSLDNVDNVKSIVKQNAGVGKINP
What is the function of this protein?
Cleaves unsaturated oligo-galacturonides from pectin.  The major product is trigalacturonate; digalacturonate and tetragalacturonate are also produced.  Activity on methylated pectins decreases with an increasing degree of methylation (By similarity).
What are the official names of this protein?
Pectate trisaccharide-lyase, Exopolygalacturonate lyase, Pectate lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYY_STAAE
Sequence: MTNVLIEDLKWRGLIYQQTDEQGIEDLLNKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPIVLIGGGTGMIGDPSGKSEERVLQTEEQVDKNIEGISKQMHNIFEFGTDHGAVLVNNRDWLGQISLISFLRDYGKHVGVNYMLGKDSIQSRLEHGISYTEFTYTILQAIDFGHLNRELNCKIQVGGSDQWGNITSGIELMRRMYGQTDAYGLTIPLVTKSDGKKFGKSESGAVWLDAEKTSPYEFYQFWINQSDEDVIKFLKYFTFLGKEEIDRLEQSKNEAPHLREAQKTLAEEVTKFIHGEDALNDAIRISQALFSGDLKSLSAKELKDGFKDVPQVTLSNDTTNIVEVLIETGISPSKRQAREDVNNGAIYINGERQQDVNYALAPEDKIDGEFTIIRRGKKKYFMVNYQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADPRH_RAT
Sequence: MGGGLIERYVAAMVLSAAGDTLGYFNGKWEFLRDGEKIHRQLAQMGDLEAIDVAQWRVSDDTIMHLATAEALMEAGSSPDLPQLYSLLAKHYRDCMGDMDGRAPGGACMQNAMQLDPDRADGWRIPFNSHEGGCGAAMRAMCIGLRFPHPSQLDTLIQVSIESGRMTHHHPTGYLGSLASALFTAYAVNGKSPRQWGKGLMEVLPEAKAYVTQSGYFVKENLQHWSYFEKEWEKYLELRGILDGKSAPVFPKPFGVKERDQFYIEVSYSGWGGSSGHDAPMIAYDALLAAGDSWKELAHRAFFHGGDSDSTATIAGCWWGVMHGFKGVNPSNYEKLEYRQRLEEAGRALYSLGSKEDTILGP
What is the function of this protein?
Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.
What are the official names of this protein?
ADP-ribosylhydrolase ARH1, ADP-ribose-L-arginine cleaving enzyme, [Protein ADP-ribosylarginine] hydrolase, ADP-ribosylarginine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
Protein: 3S11_CRYNI
Sequence: MKTLLLTLVVVTIVCLDLGYTMTCCNQQSSQPKTITTCAESSCYKKTWKDHHGTRIERGCGCPPRKPLIDLICCETDECNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 1, SNTX-1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CARB_RHILO
Sequence: MPRRTDIKSILIIGAGPIVIGQACEFDYSGTQACKALKEEGFRVILVNSNPATIMTDPELADATYIEPITPEVVAKIIAKERPDALLPTMGGQTALNTALSLRRMGVLDRYNVEMIGADATAIDKAEDRALFREAMSKIGLETPKSMLANATDVKNADRKTHEAERAALKAEKPDNLDAELDALETRWNLGEGDRKQRYISHAMAIAAQALDHVGLPAIIRPSFTMGGTGGGIAYNRAEFYDIVQSGLDASPTTEVLIEESVLGWKEYEMEVVRDKADNCIIVCSIENIDPMGVHTGDSITVAPALTLTDKEYQMMRNASIAVLREIGVETGGSNVQFAVNPADGRLVVIEMNPRVSRSSALASKATGFPIAKIAAKLAVGYTLDELENDITGGATPASFEPSIDYVVTKIPRFAFEKFPGAEPVLTTAMKSVGEVMAIGRTFQESLQKALRGLETGLTGLDEIEIPGLGHGATVANHADDRNAIRAALGTPTPDRLRMVAQAIRMGTSLEDVHAMCKIDPWFLEQIAGILAMEARIREHGIPQDAVNLRMLKAMGFSDARLASLTRTDAEVVTKIREKLDVHPVYKRIDTCAAEFASPTAYMYSTYEVPFAGALANEAQVSSRKKVVILGGGPNRIGQGIEFDYCCCHAAFALRDAGYEAIMINCNPETVSTDYDTSDRLYFDPLTAEDVLEILRAEQASGELLGVIVQFGGQTPLKLADALEKAGIPILGTSPDMIDLAEDRDRFQKLLHKLGLSQPKNGIAYSVEQARLVAGELGFPLVVRPSYVLGGRAMQIIHDESMLQSYLLDTVPGLVPEDIKQKYPNDKTGQINTLLGKNPLLFDTYLSGAIEVDVDCLCDGKATFVSGILEHIEEAGIHSGDSACSLPVHSLPSELVDELERQTAALARALNVGGLMNVQYAIKDGTVYVLEVNPRASRTVPFVAKTIGRPIAKIAARIMAGETLEDAFAHYGAMPDPRNPGHIAVKEAVFPFARFPGVDILLGPEMRSTGEVMGLDRDFALAFAKSQLGAGVDLPRSGTLFVSVRDEDKKGILPAVKRLAGLGFKVLATSGTQRFLAENGVVAEKINKVLEGRPHIEDAIRNRQVQIVFNTTDGQKAVSDSKSLRRATLMQKVPYYTTLSGAAAVAEAIAALKAGSLEVRPLQEYFA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: SEC1_YEAST
Sequence: MSDLIELQRNYLIGVLNQIETKNNLKFLIIDKTVETILSYLFLTPQELLNNVTSVDLIDSPTRKGQSSIEAIYILEPTKYNINCIDADFMVRPPKYRRCHIRFLPGLTNPIFQFFQSKRYIAQNLESFKPIELGFFVKESQFFETLQMEHSLQVFFNNNCKALIPTNVRKIVGSLVSLCVITGEYPIVRYSVSNPVEEEDARNGNAVVNANSLTRSIANAFQIAIDTYARNNPDFPPQNTERPRSILIITDRTLDPFAPILHDFSYQAMAYDLVANVDTQKDIYHYSAENEAGEQEEKVSKLVDLYDPDWIDLKHQHIMDANEYIQGRIKELIAKNPLLVDRSNVKNTTDLLSVVAHLKDFDEERRRLILHKTLVDECLGENAERKLADISAIEQNLSGFGMDFSGEKIKHIIDDLLPALAMKEPTILDKLRYIIAYALFRGGIIELDFIKLLNFIGVTHEHENFQQYLKIFRNYDLIDFKLIKDKPKDKPFQKEWFHDTLVNDPNIYHTSRFVPAVGNILSKVIANPLLLSEQYFPYLKDKPIELLNEEEFQAGLANTSANSSSSLRNPRHKAAWTTKSSNIKKNIPRQRFFYYVIGGISIPEIKAAYDQSNLKNRDIFIGSDEILTPTKFLDEVERLQNPREFFKFKEDQRQQVNPPDFLLREMKPVAQPVSHVHLKSQDNSPKSGTSSPKAAGSLKSEPPEKEKKRSKFSRFLKRKSHHDK
What is the function of this protein?
Involved in the final stage of protein secretion.
What are the official names of this protein?
Protein transport protein SEC1.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.