PharMolix/UniProtQA huggingface dataset:
Protein: RS18_SHEAM
Sequence: MARYFRRRKFCRFTAEGVAEIDYKDIATLKNYITESGKIVPSRITGTSAKYQRQLARAIKRARYLSLLPYTDLHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SYGA_GLOC7
Sequence: MSITFQSIIAKLHEFWSARGCLIAQPYDTEKGAGTMSPHTFLRAIGPEPWSVAYVEPCRRPTDGRYGENPNRFQHYYQYQVLIKPSPDNIQEIYLDSLRSLGIHPEDHDIRFVEDNWESPTLGAWGVGWEVWLDGMEITQFTYFQQCGGIDCRPVSIEITYGLERLAMYLQNVDAITKIQWNDQVNYGEIFLQNEIEQSTYNFEASTPDLLFNLFSLYEQEAKQLIERGLVIPSLDYVLKCSHSFNLLDARGVIAVAERTRYIGRIRNLAREVAQLYLQQRENLGFPLEPVQAALING
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_HISS2
Sequence: MRLIPLKTAQQVSKWAAKYIVDRINTFAPTAERPFVLGLPTGGTPLQTYKELIKLYQAEEVSFKYVVTFNMDEYVGLPKEHPESYHSFMYNNFFNHIDIQPQNINILDGNTDDHDEECRRYEEKIKSYGKINLFMGGVGVDGHIAFNEPASSLASRTRIKTLTEDTLIANSRFFDNDVTKVPKYALTIGVATLLDAEEVMLLVTGHNKALALQAGVEGNVNHFWTISALQLHRHAIFVCDEPATQELKVKTVKYFTELEQRAIHSVLD
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: NUOB_RICCK
Sequence: MKNSFYQEDEILNNKLSNRGFLLTKVDDVIGWARANSLWPMTFGLACCAVEMMQAAASRYDMDRFGMLFRPSPRQSDLMIVAGTLTNKMAPALRKVYDQMAEPKWVLSMGSCANGGGYYHFSYSVVRGCDRIVPVDIYIPGCPPTAEALIYGLMQLQKKIKRTTGFKYDSRQTY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MINE_SHEAM
Sequence: MSLLDYFRSNKKASSASLAKERLQIIVAHQRTERGAPDYFPQMKQEIIEVIRKYVYISEEQVSVQLEQNDDNLSVLELNVTLPER
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: CO1A1_MEGJE
Sequence: GGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGRPGASGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGPPGPKGNSGEPGAPGNKGDTGAKGEPGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGPGFQGLPGPAGPPGGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGSNGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGAPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGPPGPIGNVGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKEGGETGPAGRPGEVGPPGGSPGADGPAGAPGTPGPQGISGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGSSGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGPKGDRGETGPGPPGAPGAPGAPGPVGPAGKNGDRGETGPAGPAGPAGPAGARGPAGPQGPRRGFSGLQGPAGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRTGDAGPVGPPGPPGPPGPPGPP
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: FMT_ANAMM
Sequence: MKVIFMGSSEFSVPTLEFLIGSQHEVLAVYTKAPKPAGRGHLLTKTPVHAYADAHNVPVRSPASLSSDSERDIIEKYMPDAIIVASYGMILPRWMLEVPRFGCINVHPSLLPRWRGAAPMQHAILSGDAVTGVTIMQLNERLDAGDIFLQESTPIGSRENIVALSERLSSMGGRMLLKVLDNLDTMRSVSQDDAGATYAAKPSEFCVNFNDAADYICRQVRAFYPRMFFFLDGKRVKLLEADNYELAGAQIGDVVNDELHIQCGNGTVLAPKIVQPESKKPCDIRSFLRGFRGCVSNVLQR
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RLMH_METC4
Sequence: MRLLVVAIGRLKNGPERDLAARYRERAVALGKGLGVTACDLTEIPESRARRSADRIAEEAAAILALVPADAAVIACDERGRSDWPSERIADKIGAWRDAGRSTLVLVVGGADGLHETVRGRADHILAFGAATLPHGLVRVLALEQVYRALTILAGHPYHRGDPEA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACRBP_HUMAN
Sequence: MRKPAAGFLPSLLKVLLLPLAPAAAQDSTQASTPGSPLSPTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYENHGLVPDGAVCSNLPYASWFESFCQFTHYRCSNHVYYAKRVLCSQPVSILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNEIYDENSYWRNQNPGSLLQLPHTEALLVLCYSIVENTCIITPTAKAWKYMEEEILGFGKSVCDSLGRRHMSTCALCDFCSLKLEQCHSEASLQRQQCDTSHKTPFVSPLLASQSLSIGNQVGSPESGRFYGLDLYGGLHMDFWCARLATKGCEDVRVSGWLQTEFLSFQDGDFPTKICDTDYIQYPNYCSFKSQQCLMRNRNRKVSRMRCLQNETYSALSPGKSEDVVLRWSQEFSTLTLGQFG
What is the function of this protein?
Acrosomal protein that maintains proacrosin (pro-ACR) as an enzymatically inactive zymogen in the acrosome.  Involved also in the acrosome formation.
What are the official names of this protein?
Acrosin-binding protein, Acrosin-binding protein, 60 kDa form, Cancer/testis antigen 23, CT23, Cancer/testis antigen OY-TES-1, Proacrosin-binding protein sp32.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein: DXS_RUEPO
Sequence: MSDRPHTPLLDQVTRPADLKRFSDAQLTQLAGELRAETVSAVSVTGGHLGAGLGVVELTVALHAVFDTPRDKVIWDVGHQCYPHKILTERRDRIRTLRMKDGLSGFTKRSESPYDPFGAAHSSTSISAALGFAVARDLGGVTPEGLGDAIAVIGDGSMSAGMAFEAMNNAGHLKKRLIVILNDNEMSIAPPVGALSNYLSRLYAEEPFQELKAAAKGAVSLLPEPFREGAKRAKEMLKGMAVGGTLFEELGFSYIGPIDGHDMGQLLPVLRTVKARATGPILLHVLTKKGKGYAPAERARDRGHATAKFDVVTGEQKKAPSNAPSYTAVFGKALVDQAARDDKIVAVTAAMPDGTGLNLFAERYPSRCFDVGIAEQHGVTFSAALAAGGLKPFCAMYSTFLQRGYDQVVHDVAIQRLPVRFAIDRAGLVGADGATHAGSFDIAYLANLPGMVVMAAADEAELVHMVATAAAHDDGPIAFRYPRGEGVGVEMPELGKVLEIGKGRMIQKGARVALLSFGTRLTEVQKAAEALAARGITPTIADARFAKPLDRDLILNLAHDHEALITIEEGAVGGFGSHVAQLLADEGVFDHGLKFRSMVLPDIFIDQSSPADMYAVAGMNAPQIEAKVLDVLGIGRIGEKRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: AUSM_ASPCI
Sequence: MSDTSATKTEIRVIIVGGSVAGLTLAHCLAKANISHVVLEKRAEISPQEGAFLGIWPNGGRIFDQLGVYADLEQCTVPIHTMRVRFPDGFSFSSELPRCVQERFGYPIVSLDRQKVLEILHDRYPAKSNIHINKRVTEIRQTEREAQVVTDDGAVYKGDLVVGADGIHSAVRAEMWRQAKGLVGRRDGQAFAVEYACVFGISTPIPGLESGEHVNSYSDGLCVITFHGKDGRIFWFILIKLHKRFVYPKTPRFSASDAAKVCAEYASVPVWGEICVRDLWRNKTSASMTALEEGLLKTWNFKRVVLLGDSIHKMTPNIGQGANTAAEDAAVLASLLQRLSTSASSTTSGTIDAVLREYVSLRYKRVKSTYQRAYFGARLHTRDNVLKCFVGRYIFPRFSQQVLERTSQAIAGAPLVDFLPTPKRSGAGWSDYAGSPEVGAPTVPWLVISLPVLASVLCYLMFA
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of calidodehydroaustin, a fungal meroterpenoid (PubMed:28233494, PubMed:29076725).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:28233494).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:28233494).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (By similarity).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (By similarity).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (By similarity).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (By similarity).  The cytochrome P450 monooxygenase ausG modifies austinolide to austinol (By similarity).  Austinol is further acetylated to austin by the O-acetyltransferase ausP, which spontaneously changes to dehydroaustin (PubMed:28233494).  The cytochrome P450 monooxygenase ausR then converts dehydroaustin is into 7-dehydrodehydroaustin (PubMed:28233494).  The hydroxylation catalyzed by ausR permits the O-acetyltransferase ausQ to add an additional acetyl group to the molecule, leading to the formation of acetoxydehydroaustin (PubMed:28233494).  The short chain dehydrogenase ausT catalyzes the reduction of the double bond present between carbon atoms 1 and 2 to convert 7-dehydrodehydroaustin into 1,2-dihydro-7-hydroxydehydroaustin (PubMed:28233494).  AusQ catalyzes not only an acetylation reaction but also the addition of the PKS ausV diketide product to 1,2-dihydro-7-hydroxydehydroaustin, forming precalidodehydroaustin (PubMed:28233494).  Finally, the iron/alpha-ketoglutarate-dependent dioxygenase converts precalidodehydroaustin into calidodehydroaustin (PubMed:28233494).
What are the official names of this protein?
FAD-dependent monooxygenase ausM, Austinoid biosynthesis cluster protein M.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RRP1B_HUMAN
Sequence: MAPAMQPAEIQFAQRLASSEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFYCMWVQDEPLLQEELANTIAQLVHAVNNSAAQHLFIQTFWQTMNREWKGIDRLRLDKYYMLIRLVLRQSFEVLKRNGWEESRIKVFLDVLMKEVLCPESQSPNGVRFHFIDIYLDELSKVGGKELLADQNLKFIDPFCKIAAKTKDHTLVQTIARGVFEAIVDQSPFVPEETMEEQKTKVGDGDLSAEEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDTGPLLQFDYKAVADRLLEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQGKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAAPSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSPRAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTPAWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASLKKRKKMRVMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPKPLFFRRAKSSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFDPEQKPLHGVLKTPTSSPASSPLVAKKPLTTTPRRRPRAMDFF
What is the function of this protein?
(Microbial infection) Following influenza A virus (IAV) infection, promotes viral mRNA transcription by facilitating the binding of IAV RNA-directed RNA polymerase to capped mRNA.
What are the official names of this protein?
Ribosomal RNA processing protein 1 homolog B, RRP1-like protein B.
What is the protein family that this protein belongs to?
Belongs to the RRP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Note=Predominantly located in the nucleolus with a small amount found in the nucleoplasm (PubMed:20926688). Associates with the perichromatin region during metaphase and with cytoplasmic foci during telophase before reaccumulation in the nucleolus during G2 (PubMed:20926688). Associates with heterochromatin and euchromatin (PubMed:19710015). SUBCELLULAR LOCATION: Nucleus, nucleoplasm. Note=(Microbial infection) Following infection by influenza A virus, partially translocates from the nucleolus to the nucleoplasm.
Protein: ACTPC_ACTFR
Sequence: SADVAGAVIDGAGLGFDVLKTVLEALGNVKRKIAVGIDNESGKTWTAMNTYFRSGTSDIVLPHKVAHGKALLYNGQKNRGPVATGVVGVIAYSMSDGNTLAVLFSVPYDYNWYSNWWNVRVYKGQKRADQRMYEELYYHRSPFRGDNGWHSRGLGYGLKSRGFMNSSGHAILEIHVTKA
What is the function of this protein?
Pore-forming toxin (PFT) that consists of a crown-shaped octamer or nonamer that forms cation-selective hydrophilic pores of about 1. 5 nm (inside) and 13 nm (outside) (PubMed:21300287, PubMed:25716479).  It causes cardiac stimulation and cytolysis (EC(50)=1. 6 nM on erythrocytes) (PubMed:19563820, PubMed:31295915, PubMed:25759390).  Interestingly, the Phe-16 is crucial for hemolysis (PubMed:25759390).  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers (PubMed:19563820, PubMed:25716479).  It is probable that a dimeric form is an assembly intermediate before the complete oligomerization (PubMed:25716479).  The formation of stable pores occurs only in vesicles composed of DOPC/SM (there is no oligomerization when the PFT is treated with vesicles of DOPC or SM alone) (PubMed:25716479).  The transmembrane pore displays 8 lateral perforations, one at each subunit-subunit interface, partially occupied by the acyl-chain region of a bridging lipid (PubMed:25716479).  Each pore contains 24 lipid molecules, firmly bound to each subunit, that is, 3 lipids (L1, L2, L3, L4 and/or L5) are associated to each subunit (PubMed:25716479).  Lipid L1 bridges 2 subunits, whereas lipids L2 and L3 bind to sites at single subunit (PubMed:25716479).
What are the official names of this protein?
DELTA-actitoxin-Afr1a, DELTA-AITX-Afr1a, Alpha-helical pore-forming toxin, PFT, Cytolysin, Fragaceatoxin C, fraC.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey (PubMed:19563820,PubMed:21300287,PubMed:25716479).
Protein: NADK_ACIET
Sequence: MKPIFRRVAVIGKYPGPGAVSASDSARQIIESIAQFVTQQDCELTLEAETAAHTGLTQYHTLDVEGIGRQCDLCLVVGGDGTMLGVGRRLAGYGTPLVGINQGRLGFITDIPLEGYQDALTPILHGDYEEDVRPLMQACVMRGGECVFEALALNDVVVNRGSTSGMVELRVEVDGVFVSNQRADGLIVASPTGSTAYALSAGGPMLHPSIPGWVLVPIAPHTLSNRPIVLSDATEVAIEVAGGRDISANFDMQSLASLQHGDRILVRRSAHRVCFLHPRGWSYFATLRKKLGWYEGGS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_ECOLC
Sequence: MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSTB1_MAGSA
Sequence: MAIIDSFVGSSKISARDLNVHYGEKQALFDVNLDIPVGQVTALIGPSGCGKSTFLRCINRMNDLVEIARVSGSLFLDGIDIQDAAMDVVQLRARVGMVFQRPNPFPKSIYENVAFGPRLHGLAAGADELDEIVISSLDKAGLWGEVKDRMGETGTSLSGGQQQRLCIARAIAVAPEVILMDEPCSALDPIATAAVEELIDELRGSYTIVIVTHSMQQAARVSQRTGFFHLGKLIEMGETESMFTSPQHPLTQGYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LHX9_HUMAN
Sequence: MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
What is the function of this protein?
Involved in gonadal development.
What are the official names of this protein?
LIM/homeobox protein Lhx9, LIM homeobox protein 9.
What are the subcellular locations of this protein?
Nucleus.
Protein: CPLN2_XENLA
Sequence: MSVTPVLDPEWQRSPEGLDYLSRVLRHNKRKFFGLIERPVLPPHLPADVAAYKVFVCGKSGVGKTSFIAKLSGLAVPSMHHETAGIQTTCMYWPVRPSGSARPVIFRFQFWDCGEGALRKFDHILPACKEKADAVLFLFSFTDRSSFEDVPALISRTLDQDEDVTRVVIGTKLDQYMHTDVTEDDLRDFQRTWQLPVMRVRSVNGPRMTDGRDLDGRAGLAECAPVLNGLAEILWHRDQVIAGLVGGAE
What is the function of this protein?
Potential effector of the planar cell polarity signaling pathway.  Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes.  Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia.  More generally involved in exocytosis in secretory cells.
What are the official names of this protein?
Ciliogenesis and planar polarity effector 2, REM2- and Rab-like small GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: YCC1_YEAST
Sequence: MMIIIFIELCRIADSLLWIPKSSRRTSSISTYLILLPYKKWNPNNYIKIHVLFIWIPKSSRRIYNIVCIHNIIASNDNGILTIIKLPPVPQKDPCIIFIITALLTSNHECSQINLLE
What are the official names of this protein?
Putative uncharacterized protein YCL021W.
Protein: ANM12_ARATH
Sequence: MTSTENNNNGSDETQTTKLHFEDADESMHDGDDNNADVADDITSADYYFDSYSHFGIHEEMLKDVVRTKSYQDVIYKNKFLIKDKIVLDVGAGTGILSLFCAKAGAAHVYAVECSQMADTAKEIVKSNGFSDVITVLKGKIEEIELPVPKVDVIISEWMGYFLLYENMLDTVLYARNKWLVDGGIVLPDKASLYVTAIEDAHYKDDKVEFWDDVYGFDMSCIKRRAITEPLVDTVDGNQIVTDSKLLKTMDISKMAAGDASFTAPFKLVAQRNDHIHALVAYFDVSFTMCHKKMGFSTGPKSRATHWKQTVLYLEDVLTICEGETITGSMTIAQNKKNPRDVDIKLSYSLNGQHCNISRTHFYKMR
What is the function of this protein?
Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in a glycine and arginine-rich domain.  Type I arginine methyltransferase active on both histones and non-histone proteins.  Mediates the methylation of MED36A.
What are the official names of this protein?
Probable protein arginine N-methyltransferase 1.2, AtPRMT12.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: METK_STAA3
Sequence: MLNNKRLFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVDIPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEATGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYDENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLADQCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQPIYKQTAAYGHFGRTDVLFPWEKLDKVEELKDAVK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4LH_SINFN
Sequence: MVRYNAVEDPLCYPGTHVLRNRANIPDQNELDEFEQLMFDSRAREALPDGDLDFAHYRALHRHFFQDVYEWAGQTRIIRTGKGENWFCYPEYIEREANRLFAELAARDHLARTESKEAFAKGASWFLAEINAIHPFREGNGRTQLVFLTMLTRYAGYELDESKLEPKRFLDAMIRSFSGDLAPLAAEIRRMI
What is the function of this protein?
Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
What are the official names of this protein?
Probable protein adenylyltransferase y4lH.
What is the protein family that this protein belongs to?
Belongs to the fic family.
Protein: ARPC3_CAEEL
Sequence: MPAYHSKFDTELKVLPLGNTNMGKLPIRTNFKGPAPQTNQDDIIDEALTYFKPNIFFREFEIKGPADRTMIYLIFYITECLRKLQKSPNKIAGQKDLHALALSHLLPIPGENGFPLNSMYKAPQSKPDEDEMRAYLQQIRQEIGARLCDLAFPDPQDRPSKWWLCFARRRFMDKGLVGQGVNL
What is the function of this protein?
Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
What are the official names of this protein?
Probable actin-related protein 2/3 complex subunit 3, Arp2/3 complex 21 kDa subunit, p21-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.