PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_ECOUT
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_SHEB5
Sequence: MAIERTFSIIKPDAVAKNHIGAIYNRFETAGLKIVASKMLHLTKEQAEGFYAEHSERGFFGALVAFMTSGPIMVQVLEGENAVLAHREILGATNPAQAAPGTIRADFAESIDENAAHGSDAVESAAREIAYFFSAEELCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_CITBB
Sequence: MRLGILGGTFNPIHNAHLRIAEEARDLYQLDRVVFIPAATPPHKPLVGELSFASRLEMVRLAVADNPGFMVSDMEGVRGGRSYSIDTLRELKARYPDDDLFFIVGADSFNDISTWREYEAIFELCNVISVQRPGSTITSLAEALPVAIAGEFCYDPAAKRLNHCSGHAVYALDGVLLDISSSHIRLSVQGGRSIRYLLPDAVEHYIKEQRLYVDAR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: PSBM_GNEPA
Sequence: MEVNILALIAIALFISVPTAFLIIIYVKTISENN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: THIM_SHIFL
Sequence: MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLALGASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKSSQTRWTLDPVAVGALDYRRHFCHELLSFKPAAIRGNASEIMALAGIANGGRGVDTTDAAANAIPAAQTLARETGAIVVVTGEVDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTLENVASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RL33_DELAS
Sequence: MAAKGGREKIKLESTAGTGHFYTTTKNKKTMPEKMAIMKFDPKARKHVTYKEIKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS11_BACC4
Sequence: MARKTNTRKKRVKKNIEAGIAHIRSTFNNTIVTLTDTHGNALSWSSAGALGFRGSRKSTPFAAQMAAETAAKAAMEHGLKTLEVTVKGPGAGREAAIRALQAAGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RISB_BUCBP
Sequence: MKIVQETISTKTKKNIAIIISRYNNFINQHLLDGALDILKRIGQINQKNIPIIHVPGAYEIPIIASIISKQKKYNAIIALGTIIKGHTLHYSHISHAVNSGLTNISITNNIPISIGIITANNIEQAIERAGTKLGNKGSEAALTALEMINIINILAQNK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: DGTL1_RHIEC
Sequence: MTVDRRALGFGGSERAVYAADPWTTRGRLYPEDGSPTRSDFQRDRDRIVHTTAFRRLKHKTQVFIAQDGDHYRTRLTHTIEVAQIARALARALKLDEDLAEGVALVHDFGHTPFGHTGEDALHEVLLPYGGFDHNAQSLRIVTKLERRYAEFDGINLTWESLEGLVKHNGPLLTPEGAGTRGPVPQPILDYCELHDLELATYASLEAQVAAIADDIAYNTHDIDDGLRSGYLTFDMLEEIPFLAGLMAEVRARYPHLEPSRFTHEIMRRQITRMVEDVIGVAQQRLSILRPESAADIRAADRVIATFSDAMAETDRQIKALLFKRIYRNPDIMRIRAGAAQIVTDLFAAYMASPKEMQSHYWVDHIAGLADAPKARHVGDYLAGMTDTYAISAHRRLFDHTPDLR
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: NRDR_PHOPR
Sequence: MHCPFCGANDTKVIDSRLVADGHQVRRRRQCLACNERYTTFETAELVMPRVIKTDGNRDSFNEDKLRGGIQRALEKRPVSADDIERAINTIKSRLRATGEREVPSDMIGNLVMEALKELDKVAYIRFASVYRSFEDIREFGEEIAKLEK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RUVA_THEYD
Sequence: MLDFIKGKVITVKPDKIVIQTGGIGYSVKIPIRVSRYINRDEETQIFTSLIVKEESIEIYGFLESSERDLFEELIKIAGIGPKMAINILSTYDRETLYKIIDHEDIKSLSKIPGIGKKTAQRILLELRGILPSLQYEKDQKYDDILSALLNLGYKRLEAKEVLDKIYNNEKDEATIIRESLSILAGKDGK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MYH16_CANLF
Sequence: MPGGYKGECGDDVDPMPFLAPPEKERIEAMNKPYDIKKSCWVKDEKEGFIAGEIQSEQGDQVTVKTVNNQTVTVKKDDVQQMNPPKFYQASDMADMTFLNEASVLNNLRQRYTNMRIYTYSGLFCVTVNPYKWLPIYGARVANMYKGKKRTEMPPHLFSISDNAYHDMLMNRENQSMLITGESGAGKTENTKKVIQYFANVGGTGKQSSDGKGQGSLEDQIIQANPVLEAFGNAKTIRNNNSSRFGKFIRIHFGTTGKLAGADIESYLLEKSRVISQQAAERGYHIFYQILSNKKPELIESLLLVPNPKEYHWVSQGVTVVENMDDGEELQITDVAFDVLGFSAEEKIGIYKLTGGIMHFGNMKFKQKPREEQAEVDTTEVADKVSHLMGLNSGELQKGITRPRVKVGNEFVQKGQNVEQCNNSIGALGKAIYDKMFKWLVVRINKTLDTKMQRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKREGIEWVFIDFGLDLQACIDLLEKPMGIFSILEEQCVFPKATDATFKAALYDNHLGKSNNFLKPKGGKGKGPEAHFELVHYAGTVAYNITGWLEKNKDPLNETVVGLFQKSSLGLLALLFKEEEAPAGSKKQKRGSSFMTVSNFYREQLNKLMATLHSTAPHFVRCIVPNEFKQSGVVDAHLIMHQLACNGVLEGIRICRKGFPNRMQYPEFKQRYQVLNPNVIPQGFVDNKKASELLLGSIDLDVNEYKIGHTKVFFRAGILAKLEDMRDERLAKIMTMLQCRLRGFLMRIEFKKMLERRIGLKVIQRNTRKFLELRFWGWWKLYNKVKPLLNVARQEEEMKAKEEELRNAMSKTQELLSRVKELEEKMATLSQEKNDLTIQLQAEQENVIDAEERLTQMMKTKMDLESQISDMRERLEEEEGTAASLSATKRKLEGEMSDLKRDLEGLETTLAKTEKEKQALDHRVRTLTGDLSLREDSIAKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKTNSKLSTQIHELEDNWEQEKKIRAEVEKARRKAESDLKMTIDNLNDMERSKLDLEEVVKKRDMEINSVNSKYEDEQSLNSTLQRKLKEHQARIEELEEELEAERSMRAKVEKQRSDLSRDLEDLSDRLEEAGGATSAQIEQNRKREAELLKLRRELEEAALQSEAAASTLRKKHTDSMAELTEHVENLQRVKSKLEKDKQVMKAEIDDLNASMETVQKSKMNAEAHIRKLEDSLSEANAKVAELERNQAEINAVRTRLQAENGELSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEESKSRSAAMVSLANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRTEELEETKRKLAARLQEAEETAEAAQARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRVFDKMLAEWQQKCEELQVEVDSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIKELIDQLGEGGRSVHELQKLKKKLEIEKEELQVALEEAESSLEVEESKVIRIQLELAQVKADIDRRIHEKEEEFEATRKNHQRAIESLQASLEAEAKGRAEALRLKKKMETDLNEMEIQLDHANKNNSELVKTLKRLQQQIKDLQVQMDEDARQHEELREQYNLQERRLSLLQTELEEVRSGLEGSERSRKLLEQEVVEITERHNEVNIQNQSLLVVKRKLESDVQRISSEHEELISEFRSADERAKKAMTDAARMAEELRQEQDHCMHLEKIKKNYEITIKDLQAKMEEAEQLALKGGKRTIMKLEARIKELETELDGEQKQHVETVKTLRKNERRLKELVFQTEEDHKTNQRMQELVEKLQNKLKVYKRQIEEAEEQANQTLARYRKTVHELDDAEERAGMAETALNKLRTRHRVAGKGITSV
What is the function of this protein?
May play a role in masticatory muscles contraction.
What are the official names of this protein?
Myosin-16, Myosin heavy chain 16.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: FIS_SHEB9
Sequence: MFDQTTNTEVHQLTVGKIETANGTIKPQLLRDAVKRAVTNFFAQLDGQEAQEVYEMVLSEVEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: PYRF_KODOH
Sequence: MSYTARAAKHPSPVAQRLLRLMDTKKTNLCASVDVKTTAEFLSLIDKLGPYICLVKTHIDIIDDFSFDGTIKPLLELAKKHNFMIFEDRKFADIGNTVKSQYSGGVYKIAQWSDITNAHGITGAGIVNGLKEAAQETTSEPRGLLMLAELSSKGSLAYGEYTEKTVEIAKSDKEFVVGFIAQRDMGGRDEGFDWLIMTPGVGLDDKGDALGQQYRTVNEVISTGTDIIIVGRGLFGKGRDPEVEGKRYRDAGWKAYQKRLQ
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: BP26_BRUSU
Sequence: MNTRASNFLAASFSTIMLVGAFSLPAFAQENQMTTQPARIAVTGEGMMTASPDMAILNLSVLRQAKTAREAMTANNEAMTKVLDAMKKAGIEDRDLQTGGINIQPIYVYPDDKNNLKEPTITGYSVSTSLTVRVRELANVGKILDESVTLGVNQGGDLNLVNDNPSAVINEARKRAVANAIAKAKTLADAAGVGLGRVVEISELSRPPMPMPIARGQFRTMLAAAPDNSVPIAAGENSYNVSVNVVFEIK
What are the official names of this protein?
26 kDa periplasmic immunogenic protein, 28 kDa cytosoluble protein, 28 kDa outer membrane protein, CP28.
What are the subcellular locations of this protein?
Periplasm.
Protein: RNY_CHLPD
Sequence: MGIFFISLVLIVLASVVFFVGGFFLGRYFLERIGTTKILEAEERAVQIVQEAQKEANEYKELKVSEVNQEWKKKRREFDQEVVIKNNKFNQMQKQVLQKEGQLKKQSQDLRDMERKLQDQRKEIEQTMETVNLRSSELERITLEQNQRLESISNLQADEARQMLVDNMLAKAREEATETIHQIHEEAEQQAERLAEKTLLTAIQRISFEQATENALSVVHIQSDELKGRIIGREGRNIKAFENATGVDIIVDDTPEVVILSCFDPLRRELAKLTLQKLLVDGIIHPVAIEKAYEDAKKEIDDVIMSAGEETISSLQIPDMPAEVVGLIGKMKYHTVYGQNLLQHSREVAMLAGLMASELKLDARVAKRAALLHDIGLVLPESDEPHAIAGRNFLKKFNESAVVLNAVAAHHGDVVKESPIAELVDAANVISLSRPGARGAVTADGNVKRLESLEEIAKGFPGVLKTYALQAGREIRVIVEGDNVSDSQADVLAHDIARKIESEVQYPGQIKVSIIRERRSIAYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GLRX3_RAT
Sequence: MAAGAAEAAEAAVAVVEVGSARQFEELLRLKTKSLLVVHFWAPWAPQCVQMNDVMAELAKEHPHVSFVKLEAEAVPEVSEKYEISSVPTFLFFKNSQKVDRLDGAHAPELTKKVQRHVSSGSFPPSTNEHVKEDLNLRLKKLTHAAPCMLFMKGTPQEPRCGFSKQMVEILHKHNIQFSSFDIFSDEEVRQGLKTYSNWPTYPQLYVSGELIGGLDIIKELEASEELDTICPKAPKLEERLKVLTNKASVMLFMKGNKQEAKCGFSKQILEILNSTGVEYETFDILEDEEVRQGLKTFSNWPTYPQLYVRGDLVGGLDIVKELKDNGELLPILKGEN
What is the function of this protein?
Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (By similarity).  Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (PubMed:16809552, PubMed:18258855).  Required for hemoglobin maturation (By similarity).  Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity (By similarity).
What are the official names of this protein?
Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PICOT, PKC-theta-interacting protein, PKCq-interacting protein, Thioredoxin-like protein 2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cell cortex. Cytoplasm, myofibril, sarcomere, Z line. Note=Under the plasma membrane (By similarity). After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area (By similarity). In the Z line, found associated with CSRP3 (By similarity).
Protein: OUIB_DROME
Sequence: MLNIVCRVCGRQKICEKSLNLFDLVNRKYLKHLHMISGLRLVDLDDVPGFMCLCCQAELRSALAFRKLCIKTQTKWLTIEDDSSSGDEDTNDNSELESEKCAFSDFGKKKEGELVEETFQVLIEEEPMDKTLNRDAKAQLREDGIDEKCVPSQKIIKVSTKLDDQIYICELCGTHATSKPTFQRHMRKHRGERPFGCKDCDARFLSAGELRAHHRVHTGEQPFACRFCEKRYVSYMGRLIHERTHTNDRPYVCEECGKKFTTAYVLKNHMVIHTGERNFRCDICDRSFQRKAHLVTHTRSMMHLQNVKKQKS
What is the function of this protein?
Transcription factor required for ecdysteroid production in the prothoracic gland by activating transcription of the ecdysteroid biosynthesis gene spok.  Binds to the 5'-AGCTTTATTATTTAG-3' DNA sequence in the spok enhancer region.
What are the official names of this protein?
Transcription factor Ouib, Protein ouija board.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_LIMRJ
Sequence: MENRLKAKYENEIRPALIEKFNYSSVMQAPKIDKIVLNMGVGDATTNSKNLDEAVEELGLISGQKPLITKAKKSIAGFRLREGMSIGAKVTLRGERMYDFLDKLVNVALPRVRDFHGVSNKAFDGRGNYTLGIHEQLIFPEIDYDKVNRVRGLDVVIVTTAQTDEESRELLAQLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DNAK_BURL3
Sequence: MGKIIGIDLGTTNSCVAIMEGNQVKVIENSEGTRTTPSIIAYMDDNEVLVGAPAKRQSVTNPKNTLFAVKRLIGRRFEEKEVQKDIGLMPYTIVKADNGDAWVEAHGEKLAPPQVSAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAFGLDKVEKGDRKIAVYDLGGGTFDVSIIEIADVDGEMQFEVLSTNGDTFLGGEDFDQRIIDYIIGEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSSQQTEINLPYITADASGPKHLNLKITRAKLEALVEDLVERTIEPCRIAIKDAGVKVSDIDDVILVGGQTRMPKVLEKVKEFFGKDPRRDVNPDEAVAVGAAIQGQVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMISKNTTIPTKHAQVYSTADDNQGAVTIKVFQGEREMAAGNKLLGEFNLEGIPPAPRGVPQIEVTFDIDANGILHVGAKDKATGKENKITIKANSGLSEAEIDQMIKDAEANAAEDHKLRELADSRNQGDALVHSTKKALTEYGDKLDAGEKEAIEASLKSLEELLKDSSADKAAIDAKVEELGKVSQKLGEKMYADMQAQQAGAAGAAGAAEGAAHAGGAQQAADDVVDAEFKEVKKD
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SECA_BURMS
Sequence: MTTGFLQKIFGSRNQRLVKQYQKTVAAINALETQIETLTDDQLRGKTGEFRQRIAAGESLDKLLPEAFAVCREASRRVLKMRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLAAYLNALAGRGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGINLSGMEHDQKQAAYAADITYGTNNEFGFDYLRDNMVYETDSRVQRPLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMNALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERMLAEWGLIGDGESLYAPQNITLMHHVYAALRAHTLFHRDQHYVVQNDEVIIVDEFTGRLMPGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEAYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRECHERGQPVLVGTTSIENSELLSHLLKQAGLPHEVLNAKQHAREAAIVAEAGRPKRITIATNMAGRGTDIVLGGNVEKQAAFIEADESIPADEKARRIQQLHDEWETLHEQVKTAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDIAETIGAMRHGVISEVVRQFVPAGSIEEQWDLPELEETLRNDWQLDLAIQEMVNESSSINADEILDAVTTAADEHYEAKVALVGRESFSAFERSIMLQTLDRLWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAVKQEVTRIVMNVQIQSPEQLEEAAEQIEEQGGQLGNVEFQHADFAAAAAAATAGGAVVADATAEMVGHAMSHSGPAGEVPRVGRNDPCPCGSGKKYKHCHGKLN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CSL4_YEAST
Sequence: MACNFQFPEIAYPGKLICPQYGTENKDGEDIIFNYVPGPGTKLIQYEHNGRTLEAITATLVGTVRCEEEKKTDQEEEREGTDQSTEEEKSVDASPNDVTRRTVKNILVSVLPGTEKGRKTNKYANNDFANNLPKEGDIVLTRVTRLSLQRANVEILAVEDKPSPIDSGIGSNGSGIVAAGGGSGAATFSVSQASSDLGETFRGIIRSQDVRSTDRDRVKVIECFKPGDIVRAQVLSLGDGTNYYLTTARNDLGVVFARAANGAGGLMYATDWQMMTSPVTGATEKRKCAKPF
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
What are the official names of this protein?
Exosome complex component CSL4, CEP1 synthetic lethal protein 4.
What is the protein family that this protein belongs to?
Belongs to the CSL4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: ATPG_BACCZ
Sequence: MASLRDIKAKINSTKKTSQITKAMEMVSASKLNRAEQNAKSFVPYMEKIQEVVASIAQGSKGINHPMLNARPVKRTGYIVITSDRGLAGGYNSNVLRTVSNVIRERHNMDSNQYSIIVLGRLGRDYLKRRGFNIIDEVVGLSDHPSFTDIKDLASRAIAMFADGAYDELYIYYNHYVSKISQEVTENKILPLTDVASDKPTTAYEFEPSEEEILKVLLPQYAESLVYGALLDGKASEHAARMTAMKSATDNAMEVIDSLTLSFNRARQAAITQEITEIVGGAAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CAPSD_PVXXC
Sequence: MTTPANTTQAVGSTKSTTTTTAGATPANSGLFTIPDGDFFSTAKAVVASNAVATNEDLAKIQEIWKDKKIPSDTMAQAAWDLVRHCADVGSSAQTEMIGTGPYSNGVSRARLAAAIKEVCTLRQFCKKYAPVVWNWMLTNNSPPANWQAQGFKPEHKFAAFDFFDGVTNPAAITPKEGLMRPPSEAEMNAAQTAAFVKITKARAQSNDFASLDAAVTRGRITGTTVAEAVVSLPPP
What is the function of this protein?
Required for genome encapsidation.  Forms ribonucleoprotein complexes along with TGB1 helicase and viral RNA.
What are the official names of this protein?
Coat protein, Capsid protein, CP.
What is the protein family that this protein belongs to?
Belongs to the potexvirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: KATG_JANMA
Sequence: MSSEAKCPFPHAANRSRSNQDWWPNQLRVDVLNQHSNKSNPLGEKFNYAEEFKKLDYKALKADLVKLMTDSQDWWPADFGHYGPQFVRMAWHATGTYRTMDGRGGGGRGQQRFAPLNSWPDNVNIDKSRRLLWPIKQKYGQRISWADLLVLTGNVALESMGFRTFGFAGGRADVWEPDTDVNWGAETTWLGTDKRFSGDRELDENLSATHMGLIYVNPEGPDGSGDYMAAAKDIRATFYRMAMDDEEIVALIAGGHTFGKAHGAAPESHKGAEPEGAPIEAQGLGWVSNFGDGYGKDTVSSGLEVTWTKTPALWSNNFFENLFKYEWEITKSPAGAKQWVAKDAEDIIPDAHIKGKFHKPTMLTTDLTLRFDPEFGKISKRFYEDPQAFAEAFARAWFKLTHRDMGPRSRYLGPEVPKEELIWQDPIPEVDYKLVDAADVTALKAKLLTSGLSVSELVGTAWASASTFRGSDKRGGANGARIRLAPMKDWEVNQPEQLAKVLKTLEGIQADFNQSASGGKQVSLADLIVLAGSVGVEQAAKAAGVNVSVPFAAGRNDARQDQTDVESFAALEPRTDGFRNYVGKKNGVPAEVALIDKAQLLCLSVPELTVLISGLRAININVGGVKHGVLTRTPGVLNNEVLLNLLDMGTQWKPVESDANVFEGRDRKSGEVKWTATRADLVFGSNSILRSVAEVYAESDAKEKFVKDFVAAWVKVMNADRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: GATB_CLOK5
Sequence: MEFEAVIGLEVHVELLTETKIYCGCSTAFGSEPNKHVCPVCLGLPGSLPRLNKKVVEYAIKAGLALNCSINNKSRMDRKNYFYADCPKNYQITQQEIPICREGFIEIRNHLGEKKRIGIERIHMEEDAGKLIHTDEGTLIDYNRAGIPLIEIVSKPDIRTSKEAVSYLEDLRNILKFIGVSDCKMEQGSLRCDCNISIRPKHNLKLGVKTEIKNMNSFKALEKAIQYEYKRQSDLIESGEKVRQETRRWNDAKNVTEVMRSKEYANDYRYFPEGDLTAINISDNYIDNIRKTIPELPDKKIDRFVEEFKISRKEIEILILNMEIGDFFENAAKLSGDPKSVSNWITGDISRLAKETGIPLNNLNFTERDLAELIEFINCGVISNNIGKKVIEEMFYKGKSPRQIIHEKGFVQNSSKEKILKVVKEVMEENPKSIEDYKKGKKKAVKFMIGMVMKKTKGNANPMLVNKLVEEEIGKY
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.