PharMolix/UniProtQA huggingface dataset:
Protein: YA11B_YEAST
Sequence: METFTGYLKSTCFHQISPYPPSIMSIQVKVHANILILSFIECLRMPMHRQIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKLRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMNTWDTDKYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDTGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Truncated transposon Ty1-A Gag-Pol polyprotein, TY1B, Transposon Ty1 TYB polyprotein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPOC_GLUDA
Sequence: MRRMNELMKILGQTGQAMTFDQIKIQLASSEQIRSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKFRGIICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRIGLMVDMTLKDLEKILYFESYVVLEPGTSPLKQFSLLTEDQYLDVMDEHGDDGIEVGIGAEAIKKVLERIDCKADKERLRQELKDTTSEAKRKKLVKRLKLIEAFADSESRPEWMIMDLIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRAITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSKLEKYGHATTIKAAKRMVEKERPEVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILSPANGKPIIVPSQDIVLGLYYLSLETPEFLATPDRNEYDAEGRLTVTGASSFATIGEVEYALSAGAIKLHDKIVARFDTVDAEGKPVRQTVITTPGRMLIAQILPRHPAIPFSLINKQLTKKNVSDVIDAVYRHCGQKECVIFCDRMMGLGFRHAAKAGISFGKDDMIIPAEKKVLVERTAAEVKEFEQQYQDGLITAGERYNKVVDAWSRCTDEVQAAMMKEISRQEVGKVTNSVWMMSHSGARGSPAQMKQLAGMRGLMAKPSGEIIEQPIIANFKEGLSVLDYFTSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIIVEDDCGSERGLTVRAVMDGGEIVSSLSERILGRTVAADILDPATGEVLFKRDTLIEEAQAEKIEKAGVESVLIRSVLTCESRVGVCGLCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQRGAEQSMVEASRDGHVTINNRTIVHNSQNVPIVMSRNCEIVLTDDKGVERARYRVPYGARLLVEEGAAVTRNQKLAEWDPYTLPIITEHSGTVEYLDLIDSITLVERMDEVTGLTSKVVVDYKQAAKGVDLRPRLQLKDANGHVIKLSNGNDARYFLSPDSLLSVENGAQVSAGDVLARIPREGSKTRDITGGLPRVAELFEARRPKDHAIISETDGRVEFGKDYKAKRRIIVKNDETGEETDYLIPKGKHVSVQEGDFVRVGDPLVDGPRVPHDILKVLGVEALSDYLVNEIQDVYRLQGVKINDKHIEVIVRQMLQKVEILEPGDTTYLIGETVDRIEFETENTKRLNMGERPAQAMPVLQGITKASLQTQSFISAASFQETTRVLTEAATAGKKDTLNGLKENVIVGRLIPAGTGSVMNKLRAIAAGQDRQRLAQARPVVSKAD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: LYSM5_ARTBC
Sequence: MLSSVLFPAMRTLLLLKYVFSLISLSAICCQTVSAIPVVSREGLPMTLSDKCAEALISDVACDPNVLDFKPGYYYSPEILQRACTDTCKSALDSYLDRVKSSCGTETIVGPFDLEVSALIVPGMRKDLFQKTCLQDNGRYCNNVAATAAVIADPGVSRFNYLSSVPPGTVPPDPCDIQHVCLYVDDQSMRNIWATIDYYSYWVLYIINAGCYNMHRLNGTELCISAPGQKFVPGDATDLPGATVTTPVPAPSDAASGSNRYCGRWYGVKKGDYCNLIVLKFGITMDNFIFLNPALNSNCTNLYAEESYCVLPVGDINTYSGKPGYVSTPTGSETTATGIRFEDLPDATENPYPRPPPGPPIAEGTRDDCNYYFDGAEFQYNVTNTYWNSNCQIPPPQVYRVDPESFESWNAGLGNISRPECSFKPGFRYCGRYYALSDDSDEPTPTTPITTSDDPTSTSATPTTPTTSSKPSPGAPTMTGQPSACNKWHTVTNGESCTVIPKTFGITLEQFLAWNPTVKSDCTENFWAGYAYCVGVKTLGPS
What is the function of this protein?
Might have a role in sequestration of chitin oligosaccharides (breakdown products of fungal cell walls that are released during invasion and act as triggers of host immunity) to dampen host defense.
What are the official names of this protein?
LysM domain-containing protein ARB_00327.
What are the subcellular locations of this protein?
Secreted.
Protein: PPX2_MYCTU
Sequence: MALTRVAAIDCGTNSIRLLIADVGAGLARGELHDVHRETRIVRLGQGVDATGRFAPEAIARTRTALTDYAELLTFHHAERVRMVATSAARDVVNRDVFFAMTADVLGAALPGSAAEVITGAEEAELSFRGAVGELGSAGAPFVVVDLGGGSTEIVLGEHEVVASYSADIGCVRLTERCLHSDPPTLQEVSTARRLVRERLEPALRTVPLELARTWVGLAGTMTTLSALAQSMTAYDAAAIHLSRVPGADLLEVCQRLIGMTRKQRAALAPMHPGRADVIGGGAIVVEELARELRERAGIDQLTVSEHDILDGIALSLAG
What is the function of this protein?
Degradation of inorganic polyphosphates (polyP).  Releases orthophosphate processively from the ends of the polyP chain.  Prefers long-chain length polyphosphates as substrates (By similarity).  Can also hydrolyze ATP and ADP substrates, but lacks GTPase activity.  Cannot hydrolyze pppGpp to ppGpp (PubMed:22880033).
What are the official names of this protein?
Exopolyphosphatase 2, ExopolyPase 2.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family.
Protein: HTPG_XANOR
Sequence: MTVDTDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPELLEGSGELRIRVDYDKDARTVTIDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDANLIGQFGVGFYSAFIVADQVDVYSRRAGLPAREGVHWSSRGEGEFEVASVDKPERGTRIVLHLKDGEDTFADGWTLRGILKKYSDHIGLPIEMRKEHYGEAADKPAEPEWEAVNRASALWTRPKSEIKDEEYQEFYKHIAHDAGNPLAWSHNKVEGKLEYTSLLFVPGRAPFDLYHRDSAKGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSSDLSLNVSREILQSGPVVDSMKSALTKRSLDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREKIAGLMRFSSTHDTTGAQSVGLADYVSRLAEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTEFDGKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGEDVAEVRVSHRLTDSPAILAIGQGDLGLQMRQLLEASGQAVPESKPVFEFNPTHPLIEKLDAEQDMDRFCDLSQVLFDQAALAAGDSLKDPAGYVKRLNKLLLELSV
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_DECAR
Sequence: MIRFDCITLFPEMFAAVTESGITRRALEEQRWQWQGWNPRDFAENAWRRVDDRPFGGGPGMVMQPGPLEKAIAAAKSQQREAGLAKSRVIYLSPQGAPLTHERVMQLATGDEGLILLCGRYEGIDERLIERCVDEEISIGDFVLSGGELPAMVLIDAVVRQLPGVLGDAASAVEDSFVGGLLDCPHYTRPEVYEGVSVPETLMSGDHKRIRRWRLKQSLARTRKRRPDLLAHRVLSAEETQLLTEISGEEQCGE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYNT_STRTR
Sequence: XXFENFLNANXAYVNLD
What are the official names of this protein?
Putative carbonic anhydrase, Carbonate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family.
Protein: NUCS1_HALSA
Sequence: MPRTLTDPTADRAAAFATDAAADGLTVSLIGSCVATLTGRSQRDLAAGVRTLLWKPDDTVVVHGASGRDPDAWASGGPVTVDAADGLTVACDGGHTAGALRVRFDAVHTATAFDAAGADATTVSGTEAALKDRVLDTPDLVEPGFQPLATERDTPAGPIDIYGRDADGTVTAVELKNVRAGPAAASQLQRYVAALRRTLHADATVRGILVAPAVTAKTRRLLADRGLTFSPVSPPGSRDR
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS 1.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM44_HUMAN
Sequence: MAEVGRTGISYPGALLPQGFWAAVEVWLERPQVANKRLCGARLEARWSAALPCAEARGPGTSAGSEQKERGPGPGQGSPGGGPGPRSLSGPEQGTACCELEEAQGQCQQEEAQREAASVPLRDSGHPGHAEGREGDFPAADLDSLWEDFSQSLARGNSELLAFLTSSGAGSQPEAQRELDVVLRTVIPKTSPHCPLTTPRREIVVQDVLNGTITFLPLEEDDEGNLKVKMSNVYQIQLSHSKEEWFISVLIFCPERWHSDGIVYPKPTWLGEELLAKLAKWSVENKKSDFKSTLSLISIMKYSKAYQELKEKYKEMVKVWPEVTDPEKFVYEDVAIAAYLLILWEEERAERRLTARQSFVDLGCGNGLLVHILSSEGHPGRGIDVRRRKIWDMYGPQTQLEEDAITPNDKTLFPDVDWLIGNHSDELTPWIPVIAARSSYNCRFFVLPCCFFDFIGRYSRRQSKKTQYREYLDFIKEVGFTCGFHVDEDCLRIPSTKRVCLVGKSRTYPSSREASVDEKRTQYIKSRRGCPVSPPGWELSPSPRWVAAGSAGHCDGQQALDARVGCVTRAWAAEHGAGPQAEGPWLPGFHPREKAERVRNCAALPRDFIDQVVLQVANLLLGGKQLNTRSSRNGSLKTWNGGESLSLAEVANELDTETLRRLKRECGGLQTLLRNSHQVFQVVNGRVHIRDWREETLWKTKQPEAKQRLLSEACKTRLCWFFMHHPDGCALSTDCCPFAHGPAELRPPRTTPRKKIS
What is the function of this protein?
Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
What are the official names of this protein?
Probable tRNA (uracil-O(2)-)-methyltransferase, Methyltransferase-like protein 19.
What is the protein family that this protein belongs to?
Belongs to the TRM44 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_BARHE
Sequence: MVTFFENELSAKKRNQRRGFLFILSSPSGAGKSTLSRLLLKDGKLELSISMTTRQKRPSEVDGLHYHFISKKEFKRKRDGNEFIEWAEVHGNYYGTLRESVENVLSTGRDMLFDIDYQGTKQLQKKMPGDTVSVFILPPSMKELISRLYRRAEDSQDIINLRLKNARTEMQHWRSYDYVIINENLNQSVSLIKSIYLAETVKRERCFFLEPFINGLIAEKID
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS28B_CANAL
Sequence: MDAKTPVTLAKVIKVLGRTGSRGGVTQVRVEFLEDASRTIVRNVKGPVRENDILCLMESEREARRLR
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S28B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: RS6_STRPJ
Sequence: MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWEKRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RL32_BARQU
Sequence: MAVPKRKTSPSKRGMRRSADALKAPTYIEDKNSGELRRPHHIDLKTGMYRGRSVLPPKD
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ATPE_RICRS
Sequence: MNATILVKIITPLSIALEKQAKIVTMSGEEGMFGVLPSHVPMIVSLKAGLVQVYIDDMHKSENTYLISGGVTEVTANYINIATETAINVTNLSEAEIATKLLDLQKTLSDQH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DNLJ_GRABC
Sequence: MTNPDSPSLSLTPPEALSPAEARAELERLASRIAELDDAYYRDDAPLVTDADYDALRQRNAEIERLFPDAILKNSPANRVGTAPSSAFAKIRHRVPMLSLDNVFDTEEFAEFCARARRFLNLPASPRFVAEPKIDGLSISLTYENGILTRAATRGDGMEGEDVTANVRTLRDVPQTLHGEAPAFIEIRGEVFMSKAAFLELNETQARLGQKIFANPRNAAAGSLRQLDASVTANRPLALFAYAQGESSAPVAETHWDYLTRLKDWGFVVNPLSQLIEDENAAAAFTTRIAAGRSTLPYDIDGVVFKIDDLSLQRRLGFVGRAPRWATAWKFPAEQATTVLEKIDIQVGRTGALTPVAHLQAVNVGGVLVTRATLHNEDEIARKDVREGDTVILQRAGDVIPQIVSVVLEKRPDGARPFAPLEHCPVCGSLAIRPPGEVVRRCTGGLTCEAQVVERLIHMVSRPAFDIDGLGEKSILEFHRDGLVSGPADIFRLPAREDEIARRDGWGSLSARNLSQAIEARRSIPFDRFLYALGIRRIGETNARLLARHYGSFTEWRTQMLAARQIGSDERLALGSITGIGPTIAEELVDFFAEPRNIDTLDELAGMLTITAPSGGLSSAALDSPLNGKIIVFTGTLQAMTRPEAKARAESMGAKVTDSVSKKTDFVVTGADAGSKAKKAAELGIRTLSEEEWLALAGGG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DLD_ARATH
Sequence: MAFASKFARSKTILSFLRPCRQLHSTPKSTGDVTVLSPVKGRRRLPTCWSSSLFPLAIAASATSFAYLNLSNPSISESSSALDSRDITVGGKDSTEAVVKGEYKQVPKELISQLKTILEDNLTTDYDERYFHGKPQNSFHKAVNIPDVVVFPRSEEEVSKILKSCNEYKVPIVPYGGATSIEGHTLAPKGGVCIDMSLMKRVKALHVEDMDVIVEPGIGWLELNEYLEEYGLFFPLDPGPGASIGGMCATRCSGSLAVRYGTMRDNVISLKVVLPNGDVVKTASRARKSAAGYDLTRLIIGSEGTLGVITEITLRLQKIPQHSVVAVCNFPTVKDAADVAIATMMSGIQVSRVELLDEVQIRAINMANGKNLTEAPTLMFEFIGTEAYTREQTQIVQQIASKHNGSDFMFAEEPEAKKELWKIRKEALWACYAMAPGHEAMITDVCVPLSHLAELISRSKKELDASSLLCTVIAHAGDGNFHTCIMFDPSSEEQRREAERLNHFMVHSALSMDGTCTGEHGVGTGKMKYLEKELGIEALQTMKRIKKTLDPNDIMNPGKLIPPHVCF
What is the function of this protein?
Catalyzes the stereospecific oxidation of D-lactate to pyruvate.  Involved in the detoxification of methylglyoxal and D-lactate, but probably not involved in the metabolization of glycolate.
What are the official names of this protein?
D-lactate dehydrogenase [cytochrome], mitochondrial, AtD-LDH, D-lactate ferricytochrome C oxidoreductase, Glycolate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GREA_FLAJ1
Sequence: MSKVSYYTADGLKKLKDELEHLKSVMRPKASQDIADARDKGDLSENAEYDAAKEAQGLLEMRIAKLEEVYANARLIDESQLDVSKVLVLSNVKIKNQSNGMEMKYTLVAESEADLKTGKISVTSPIGKGLLGKSVGEIAEITVPNGTLKFEILEITRE
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: DEOC2_VIBVY
Sequence: MSDLKAAALRALKLMDLTTLNDDDTDAKVIALCHDAKTPVGNTAAICIYPRFIPIAKKTLREQGTPEVRIATVTNFPHGNDDIEIAVAETKAAVAYGADEVDVVFPYRALMAGDEKVGFELVKQCKEACGDILLKVIIETGELKEEALIKKASQICIEAGADFIKTSTGKVPVNATPEYARMMLEVIRDMGVAEKVGFKPAGGVRTAEDAAAYLAMADDILGSEWADNMHYRFGASSLLTNLLNTLEVTDQVADPAAY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase 2, DERA 2, 2-deoxy-D-ribose 5-phosphate aldolase 2, Phosphodeoxyriboaldolase 2, Deoxyriboaldolase 2.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_THEPA
Sequence: MKFEGLFLVFNSVSGNHKIIGISYLWLAYWFGMIGFYMSVLIRTELSMSGLKIITMDTLEIYNLLFTLHGLIMVFFNIMTGLFGGIGNYLYPVLLGYCDVVYPRVNLYSLLFQPIGFVLVVSSIYLEIGSGTGWTLYPPLSTSLSNVGIDFIIFGLLAAGIASTLSSVNFITTFTSVKTIGFVIDRISPAAWSIVLTSFLLLLSLPVVTAVFLMVFLDRHYNTMFFESSNSGDPVLYQHLFWFFGHPEVYIMILPGFGIISLLLSTYTTKEMFGNQTMILAMGFNSFVRLFGLGTSYVHIRFGSRYSRYFTTVTILIALPTGNKIFNWVTTLQCVESIKSLGLVLFTVLFIVNFVIGGTTGVVLGNAGIDLALHDTVYVVGHFHFVLSIGAIISMICFIIYIQRMLLFGIILSNRLSSLIAPIFMISVLLTFLPMHFTGFSPLPRRIPDYPDEMWGWNFICTLGATMMLVLKLAILFIISL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GCSH_ECO55
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: SPRM_HALRO
Sequence: MAAINVIFISGAIALFALTGSCSESTNPFTNKPYATQNPYSPPQTNQPTKRPYQPGPAPTPAPYIPQKTNPPTKRPLNPTPSPTAKPPSENSESENSEGPVLIEEDHFTVDANFKCGIPPVEPDLKKGKIVGGAEAVPNSWPYAAAFGTYDISGGKLEVSQMCGSTIITPRHALTAAHCFMMDPDIDQTYYIFMGLHDETTYKGVRPNKIVGVRYHPKTNVFTDDPWLVYDFAILTLRKKVIANFAWNYACLPQPKKIPPEGTICWSVGWGVTQNTGGDNVLKQVAIDLVSEKRCKEEYRSTITSKSTICGGTTPGQDTCQGDSGGPLFCKEDGKWYLQGIVSYGPSVCGSGPMAAYAAVAYNLEWLCCYMPNLPSCEDIECDESGEN
What is the function of this protein?
Trypsin-like protease with a narrow substrate specificity.  Preferentially hydrolyzes substrates with Pro in the P2 position and Val in the P3 position.  Plays a role in fertilization.
What are the official names of this protein?
Spermosin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Localized on the sperm head. Released into the surrounding seawater in response to the sperm reaction, a large proportion remains associated with the sperm cell surface.
Protein: RLMG_PHOPR
Sequence: MKPALTLHDRTLKLNRFPIRKIETLQAWDAADEYLINHTHDMELDPQRPILILNDSFGALSCWFAERANVTTVTDSFVAKQGCIANLTANQLPSVNIIDCLAELPKNPQLVLIKLPKNNRLLTWQLQQLCHLLPEDCRVIGAAKVKDIHTSTLKLCDKYLGETKTSLAVKKARLVFIKPNASLAKPMPEAKAWDVPEHGIRLSNHANVFSGESLDIGARLLLNHIPQDFKYKDIIDLGCGNGVIGIKAARRNPQAKITCVDESFMAAASCTENAKQNLEAPEQLTAIVTDCLADIEHSSADLVLCNPPFHQQTTITDHIAWQMFCDAKQVLRPKGELIVIGNRQLGYDDKLKRLFGNVEIIAQNDKFIVYQSVK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRA_HAEIN
Sequence: MENIDIRGARTHNLKNINLTIPRNKLVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDSIEGLSPAISIEQKSTSHNPRSTVGTITEIYDYLRLLFARVGEPRCPDHNVPLTAQTISQMVDKVLSLPEDSKMMLLAPVVKNRKGEHVKILENIAAQGYIRARIDGEICDLSDPPKLALQKKHTIEVVVDRFKVRSDLATRLAESFETALELSGGTAIVAEMDNPKAEELVFSANFACPHCGYSVPELEPRLFSFNNPAGACPTCDGLGVQQYFDEDRVVQNPTISLAGGAVKGWDRRNFYYYQMLTSLAKHYHFDVEAPYESLPKKIQHIIMHGSGKEEIEFQYMNDRGDVVIRKHPFEGILNNMARRYKETESMSVREELAKNISNRPCIDCGGSRLRPEARNVYIGRTNLPIIAEKSIGETLEFFTALSLTGQKAQIAEKILKEIRERLQFLVNVGLNYLSLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLRNLGNTVIVVEHDEDAIRAADHIIDIGPGAGVHGGQVIAQGNADEIMLNPNSITGKFLSGADKIEIPKKRTALDKKKWLKLKGASGNNLKNVNLDIPVGLFTCVTGVSGSGKSTLINDTLFPLAQNALNRAEKTDYAPYQSIEGLEHFDKVIDINQSPIGRTPRSNPATYTGLFTPIRELFAGVPEARARGYNPGRFSFNVRGGRCEACQGDGVLKVEMHFLPDVYVPCDQCKGKRYNRETLEIRYKGKTIHQVLDMTVEEAREFFDAIPMIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKLATELSKRDTGKTLYILDEPTTGLHFADIKQLLEVLHRLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGQIIATGTPEQVAKVTSSHTARFLKPILEKP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_ANADF
Sequence: MSSQTAPRRRVTIHELRRMKDAGEKIAVVTAYDATAARLADAAGVDVVLVGDSLGMVVQGHESTLPVTLEHMIYHSAAVRRGLARSSGRAHLVGDMPFGSYQASADEAVKSAMRLVAEGGVESVKLEGGAEFVEVIRRIARAGVPVMGHIGLTPQAVHRMGGYVVQGKDSEKAQQLLRDARALELAGCYAIVLECIPAELARIISSQLRIPTIGIGAGLHCDGQVLVLNDLLGMDDAFTPKFVKRFGEIGQAISTAVGAYVGEVKRRVFPDDAHSFHSSTVRLVPAAPVDEDDGEPSGGVMGAPV
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_SALDC
Sequence: MNIIKANVAAPDARVAITIARFNQFINDSLLDGAVDALTRIGQVKDDNITVVWVPGAYELPLATEALAKSGKYDAVVALGTVIRGGTAHFEYVAGGASNGLASVAQDSGVPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.