PharMolix/UniProtQA huggingface dataset:
Protein: OXLA_BOTPI
Sequence: ADDKNPLEEFRETNYEVFLEIAKNGLKATSNPKRVVIVGAGMAGLSAAY
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:16809041).  Is highly active on L-Phe, L-Tyr, L-Trp, L-Leu, L-Met, and L-Ile, is moderately active on L-Val, and L-His, and is no or weakly active on L-Ala, L-Arg, L-Pro, L-Thr, L-Ser, L-Glu, L-Gly, and L-Lys (PubMed:16809041).  Exhibits diverse biological activities, such as edema, antibacterial (E. coli, and P. aeruginosa) and antiparasitic activities against leishmania (as a result of enzyme-catalyzed hydrogen peroxide production), induction of platelet aggregation as well as cytotoxicity on S180 tumor, human breast (SKBR-3), acute T cell leukemia (Jurkat) cancer, and Erlich ascitic tumor (EAT) cell lines (PubMed:16809041).  Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation.  These different effects are probably due to different experimental conditions.  This protein may also have activities in hemorrhage, hemolysis, and apoptosis.
What are the official names of this protein?
L-amino-acid oxidase, BpirLAAO-I, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBN_SALCH
Sequence: MELIFLGTSAGVPTRSRNVTAILLHLQHPTQPGVWLFDCGEGTQHQMLNTAFHPGKLERIFISHLHGDHLFGLPGLLCSRSMAGNPHPLTVYGPQGVREFIATTLRLSGSWTDFPLQIEEISAGDILDDGLRKVTAFRLEHPLECYGYRVVEHDKPGALNARALKAAGVTPGPLFQALKAGKTVTLADGRQINGADYLAPAVAGKSVAIFGDTAPCEAALALAQGVDVMVHETTLDASMEEKANARGHSSTRQTATLAREAAVGRLIMTHISSRYDDKGCQRLLAECRAIFPATELAYDFSVFPV
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.
Protein: TRPD_STRPS
Sequence: MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALKMKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGGIHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKYIMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVAGPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLSVLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ATPG_THISH
Sequence: MAGAKEIRTQIKSIKNTQKITKAMEMVAASKMRKAQDRMLATRPYAEKIRQVIGHVAMAKAEYKHPYLEEREVKRVGMIIISTDRGLCGGLNINLFKKAVLAMREWHDKGVEVDLCLVGNKALGFFKRLGGNVVGKVNQLGDQPRMNDLIGTIKVMLDAYDEGRIDRLVLVENEFVNTMTQKPRATTLLPLVPSEEDELKHHWDYIYEPDAKPVLDTLLTRYIESVVYQGVVENVACEMAARMVAMKSASDNAGDLIKELQLVYNKARQAAITQEISEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS2_PHYAS
Sequence: MAVVTMKQLLESGTNFGHSTRKWNPKMKKYIFTSRNGIHIIDIKKTSEKIEEAYQELSKIVNQGGKVLFLGTKKQIQTSIMEESKRCGQYYVNHRWLGGILTNFHTILKRIQLLHDLHKQEEDGVWKKLPKKEVVQLKRKRDKLEKFLGGIKDMKELPQALFVVDLEKEKNAVAEARKLNIKVFSMVDTNCDPDLVDYIIPANDDAIRSVKLITWIIANACIEGSGGVAEKPEQFDAKNVLKPKLPYQPNRRPYQETVKK
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ELP6_DANRE
Sequence: MFPELNSLLNASPDTFKPGDFILLSDRQADASFLIHHYLSFYLRAGCKVCFLGLVQSFSHYSAVGQRLGVSLTQAREKGQLVFLEGLKDSIGAILKEDTSEGTQALSYLRSPRAGLEGLFRFVESSLCQSGDDGPPVLIIDDLSVLLSLGVSAGAILDFTLYCRATVCSELQGNMVILVRCEEEDADDDEEGLNLLQRGLVHQCHLALHVEGLPTGYCRDIHGQMEVWWRQGENDAYNQRKIFQFKVHDKGASFFTRGTSRAVL
What is the function of this protein?
Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity).  The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).
What are the official names of this protein?
Elongator complex protein 6, Protein TMEM103.
What is the protein family that this protein belongs to?
Belongs to the ELP6 family.
Protein: NU5C_AETCO
Sequence: MEHTYQYSWIIPFIPLPVPILLGGGLLLFPTATKNLRRTWSFLSIFLLSIVMIFSLYLSIQQIIISCIHQNVWSWTINNDLSFEFGYFIDPLTCIMLILITTVGILVLIYSDNYMSHDQGYLRFFAYMGFFNTSMLGLVTSSNLIQIYFFWELVGMCSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGLYWVTGSFEFQDLFEIFNNLILNNRVNLLFLTLCAFLLFMGPIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFIVIPSIMYIISLIGIITILLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSIIHSMEAIVGYSPDKSQNMILMGGLTKHVPITKTAFLLGTLSLCGIPPLACFWSKDEILTDSLLFSPIFAIIACSTAGLTAFYMFRIYLLTFEGHLNTYFLNYSGKKSSSFYSISLWGKEDEKKINRNFCLVPLLTMNNKKGASFFSKKTYKINNNVRNKTLITVANGALNKRTFYYPHESDNTILFPMLVLLLFTLFIGAIGIPLNQEGFDILSKLFTPSINLLHKNSTNFVDWYEFFRNATFSVSIAFFGIFIAYCLYKPFYSSLLNLTLLNSFQKWSSNPICWEKLINCLYNWSYNRAYIDTFYKKSLTESIRRLAKQIHFFDKRIIDGITNGVGITSFFVAEFTKYIGGSRISSYLFLYLSYVFLFFLFLKILN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AGRB3_HUMAN
Sequence: MKAVRNLLIYIFSTYLLVMFGFNAAQDFWCSTLVKGVIYGSYSVSEMFPKNFTNCTWTLENPDPTKYSIYLKFSKKDLSCSNFSLLAYQFDHFSHEKIKDLLRKNHSIMQLCNSKNAFVFLQYDKNFIQIRRVFPTNFPGLQKKGEEDQKSFFEFLVLNKVSPSQFGCHVLCTWLESCLKSENGRTESCGIMYTKCTCPQHLGEWGIDDQSLILLNNVVLPLNEQTEGCLTQELQTTQVCNLTREAKRPPKEEFGMMGDHTIKSQRPRSVHEKRVPQEQADAAKFMAQTGESGVEEWSQWSTCSVTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAESRECYNPECTANGQWNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQCEGTGEEVRRCNEQRCPAPYEICPEDYLMSMVWKRTPAGDLAFNQCPLNATGTTSRRCSLSLHGVAFWEQPSFARCISNEYRHLQHSIKEHLAKGQRMLAGDGMSQVTKTLLDLTQRKNFYAGDLLMSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDEENKEKWEDAQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVLTDINFPMKGRKGMVDWARNSEDRVVIPKSIFTPVSSKELDESSVFVLGAVLYKNLDLILPTLRNYTVINSKIIVVTIRPEPKTTDSFLEIELAHLANGTLNPYCVLWDDSKTNESLGTWSTQGCKTVLTDASHTKCLCDRLSTFAILAQQPREIIMESSGTPSVTLIVGSGLSCLALITLAVVYAALWRYIRSERSIILINFCLSIISSNILILVGQTQTHNKSICTTTTAFLHFFFLASFCWVLTEAWQSYMAVTGKIRTRLIRKRFLCLGWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCGVVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQGFVIVMVHCILRREVQDAFRCRLRNCQDPINADSSSSFPNGHAQIMTDFEKDVDIACRSVLHKDIGPCRAATITGTLSRISLNDDEEEKGTNPEGLSYSTLPGNVISKVIIQQPTGLHMPMSMNELSNPCLKKENSELRRTVYLCTDDNLRGADMDIVHPQERMMESDYIVMPRSSVNNQPSMKEESKMNIGMETLPHERLLHYKVNPEFNMNPPVMDQFNMNLEQHLAPQEHMQNLPFEPRTAVKNFMASELDDNAGLSRSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQELNQKFQTLDRFRDIPNTSSMENPAPNKNPWDTFKNPSEYPHYTTINVLDTEAKDALELRPAEWEKCLNLPLDVQEGDFQTEV
What is the function of this protein?
Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity).  Promotes myoblast fusion through ELMO/DOCK1 (PubMed:24567399).
What are the official names of this protein?
Adhesion G protein-coupled receptor B3, Brain-specific angiogenesis inhibitor 3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KUP2_AERHH
Sequence: MNGNHKQALSGVTLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVEPASILGFLSLIFWLLILVVSVKYLSFVMRADNAGEGGILTLMSLATRNTPAKWTPLLIILGLIGGSFFYGEVVITPAMSVMSAIEGLNIAAPSLDPYIVPLSVLVLTLLFAIQKHGTATVGKLFAPIMLTWFITLAVLGLNSIFQHPEVLGALNPVWALRFFAKYQTASFFALGAVVLAITGVEALYADMGHFGKSPIRRAWFMVVLPSLVLNYFGQGALLLAHPEAITNPFFLLAPKWALLPLLLLATLATVIASQAVISGVFSLTRQAVRLGYLSPIRIVHTSEQESGQIYIPVINWMLYISVVIVIMSFEHSSNLAAAYGIAVTGTMVLTSILSCSVARHSWHWNKYLVAALFVALLAIDVPLFAANLAKIFSGGWLPLTLGAVMFTVMTSWKSERFQLIRRLNEHGNSLEPMIASLEKSPPTRVAGTAVYMSRVVNVIPHALLHNLKHNKVLHERIILLTLRVEEVPYVHNVRRVCIEQLSPTFWRVVASYGWRETPNVEEIFHRCNAEGLSCRMMETSFFMAHESLIMKERPWYLYLRGKLFMLLQRNALRAPDQFEIPPNRVIELGSQVDI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSLV_BACCQ
Sequence: MGNFHATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEMFEGKLEEYNGNLQRAAVEMAKQWRGDKMLRQLEAMLIVMDKTTMLLVSGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLTAKQIAKASLNIAGDICVYTNHNIIVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP416_ARATH
Sequence: MLRRWNIVIESLRRVHSSDLENLISASLYNRTLCTASESLNHGVVDESYVLAELSSLLPISSNKTSVSKEDSSSKNQVAIDSFLSAEDKLRGVFLQKLKGKSAIQKSLSSLGIGLSIDIVADVLNRGNLSGEAMVTFFDWAVREPGVTKDVGSYSVILRALGRRKLFSFMMDVLKGMVCEGVNPDLECLTIAMDSFVRVHYVRRAIELFEESESFGVKCSTESFNALLRCLCERSHVSAAKSVFNAKKGNIPFDSCSYNIMISGWSKLGEVEEMEKVLKEMVESGFGPDCLSYSHLIEGLGRTGRINDSVEIFDNIKHKGNVPDANVYNAMICNFISARDFDESMRYYRRMLDEECEPNLETYSKLVSGLIKGRKVSDALEIFEEMLSRGVLPTTGLVTSFLKPLCSYGPPHAAMVIYQKSRKAGCRISESAYKLLLKRLSRFGKCGMLLNVWDEMQESGYPSDVEVYEYIVDGLCIIGHLENAVLVMEEAMRKGFCPNRFVYSRLSSKLMASNKTELAYKLFLKIKKARATENARSFWRSNGWHF
What are the official names of this protein?
Putative pentatricopeptide repeat-containing protein At5g43820.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: F16PA_ACIAC
Sequence: MAQRISLTRYLVEQQRVDGLIPSQLRLLLEVVARACKHISHAVNKGALGGVLGSASSENVQGEIQKKLDIIANEVLIEANEWGGHLAAMASEEMDSIYVVPNRYPQGEYLLLFDPLDGSSNIDVNVSIGTIFSVLKKPEGHPGVTTEDFLQAGSSQVAAGYCIYGPQTTLVLTVGDGVAMFTLDREQGSFVLVEENVKIPADTREFAINMSNMRHWDAPVKRYIDECLAGTEGPREKDFNMRWIASMVADVHRILTRGGIFLYPWDKREPNKPGKLRLMYEANPMSWLIEQAGGAATNGKERILDIQPKQLHERVSVILGSKNEVERVTRYHSGI
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_LACPL
Sequence: MEVHNVELVMSAVAPSQYPTTGFPEIGLAGRSNVGKSSLINVLINRNSYARTSSQPGKTQTLNFYKVEDQLYFVDVPGYGYAKVSKKEREKWGQMIETYLTSRETLRGVVILVDARHAPTKDDVAMYEWMRYYEMPLLVVATKSDKIPRGKWNKQESLIKKTLNFQAEDDFIAFSAKTKEGKDAVWQWIEAHTVGGN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NIFA_RHILE
Sequence: MIKPEARLHILYDISKELISSFPLDNLLKAAMNALVEHLRLRDGGIVIHGSGGEPWINVRAPIGDDVRSRSLTIEQADAINRVIASGEKHFGKNSVVLPVKVNRKAIGALWIDFAQKSGAQDESLLAMIAVLIGLTCQRDRELCSDGGSVAEEQQAGQIPKIKPKPHPTQLDKIDWIVGESPALKRVLATTKIVAATNSAVLLRGESGTGKECFARAIHALSIRKSKAFIKLNCAALSETVLESELFGHEKGAFTGALLQRAGRFELANGGTLLLDEIGDVSPQFQAKLLRVLQEGEFERLGGTKTLKVDVRVICATNKNLEVAVLRGEFRADLYYRINVVPIILPPLRQRDGDISLLAQVFLEQFNNANDRNCDFGPSAIDILSKCAFPGNVRELDNCVQRTATLASSNTITSSDFACQQDQCSSALLRKADGDGIGNDAMNGLNSRDTMSGGLCAHAGTPSGAAATIEAAGLTERDRLIKAMERAGWVQAKAARILGKTPRQVGYALRRHRIDVKKE
What is the function of this protein?
Required for activation of most nif operons, which are directly involved in nitrogen fixation.
What are the official names of this protein?
Nif-specific regulatory protein.
Protein: 3AHD_EGGLE
Sequence: MGIYVITGATSGIGAKTAEILRERGHEVVNIDLNGGDINANLATKEGRAGAIAELHERFPEGIDAMICNAGVSGGKVPISLIISLNYFGATEMARGVFDLLEKKGGSCVVTSSNSIAQGAARMDVAGMLNNHADEDRILELVKDVDPAIGHVYYASTKYALARWVRRMSPDWGSRGVRLNAIAPGNVRTAMTANMLPEQRAAMEAIPVPTHFGEEPLMDPVEIANAMAFIASPEASGINGVVLFVDGGTDALLNSEKVY
What is the function of this protein?
Involved in the modification of secondary bile acids into iso-bile acids (3beta-bile acids) via epimerization of the 3-OH group through a 3-oxo-intermediate.  Catalyzes the oxidation of deoxycholate (DCA) and lithocholate (LCA) to yield 12-alpha-hydroxy-3-oxo-5-beta-cholan-24-oate (3-oxo-DCA) and 3-oxo-5-beta-cholan-24-oate (3-oxo-LCA), respectively.  Is also able to catalyze the oxidation of cholate (CA) and chenodeoxycholate (CDCA) into 3-dehydrocholate (3-oxo-CA) and 7-alpha-hydroxy-3-oxo-5-beta-cholan-24-oate (3-oxo-CDCA), respectively.  Can also catalyze the reverse reactions in vitro.  Prefers NADH to NADPH as cosubstrate.  The conversion of the abundant bile acid DCA into isoDCA by the gut bacterium E. lenta favors the growth of the keystone commensal genus Bacteroides, since isoDCA is less cytotoxic than its parent compound, DCA; iso-bile acids have thus a potential role in modulating gut community composition.
What are the official names of this protein?
3alpha-hydroxysteroid dehydrogenase, 3alpha-HSDH, 3alpha-hydroxycholanate dehydrogenase (NAD(+)), NAD-dependent bile acid 3alpha-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: GLGA_THEP1
Sequence: MKVVFVSYEVFPFAKVGGLADVAGTLPKYLKKHGVDVTIVMPKHRIVEKNAEKFGYEIKKVAEGLSVSHVKTDQKFDIYESVLPGSDVKTYFVANDYYFSAEDVYAGPDLGEQAIFFCAATLDLVKHLDLKPDIVHVNDWQTALIPVYLKTVYRDDPYFSRTATVLTIHNLGYQGVFDPKYLSFAGLPDYVFTIDGLEFYRQLNFLKGGIVFSDVINTVSPTYAEEIQTEEYGEKLEGVLRMRSKDLYGILNGIDYELYNPATDRYIYVNYDVNRLELKWENKVKLQEELGLPVNKETAVAGLISRLVPQKGLDLLVDVMDYLMLFDLQIVVLGTGDEQYENAFRKFQERYPDKVSANIKFDVELAQKIYAGADIFLMPSRYEPCGLGQMFSMRYGTIPVVRYTGGLADTVKEYDPQSMEGTGFGFKKYDSAHLLKAVSKALHFYYREKDHWRRIMTNAMNTDLSWDRSAKEYVDLYKKALAKVGR
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: YTHD3_HUMAN
Sequence: MSATSVDQRPKGQGNKVSVQNGSIHQKDAVNDDDFEPYLSSQTNQSNSYPPMSDPYMPSYYAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFLGQHGFNFFPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLSKVPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQTIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPRNRGAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEKLKAINNYNPKDFDWNLKNGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSGHFCGVAEMKSVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRERNRNKQ
What is the function of this protein?
Has some antiviral activity against HIV-1 virus: incorporated into HIV-1 particles in a nucleocapsid-dependent manner and reduces viral infectivity in the next cycle of infection (PubMed:32053707).  May interfere with this early step of the viral life cycle by binding to N6-methyladenosine (m6A) modified sites on the HIV-1 RNA genome (PubMed:32053707).
What are the official names of this protein?
YTH domain-containing family protein 3, DF3.
What is the protein family that this protein belongs to?
Belongs to the YTHDF family. YTHDF3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, P-body. Cytoplasm, Stress granule.
Protein: RL3_SULIY
Sequence: MGHRKLASPRRGSAGLRPRKRSSELLPTPRTWPQINSPNPKLLGFVGYKVGMSHVFMIDDWPNSPTNGKEIYMPVTVLEVPPIIPLALRAYAVDGKGEPNVITEYWSPSSLQFLDITRRIHSLSSFLKNDESKKKFEEKFGSKLDLIKSNLDRIVYFRLLVATQPRKIPSLGKKVPDLVEIQIGGGEKKAQLDYALNVLGKEISIKDVFKEGQLIDVVGVTKGKGFAGVIKRYSVVELPRWHKHRKGSRKIGTRGPSLGTPSYTPQPGQLGFHRRTEYNKRIIKIGDDPKEINPAGGFVRYGIVRNTYILLEGSILGSKKRPIFLREAVRPSYVFENAPKITYVNLLSKQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL35_PHOLL
Sequence: MPKIKTVRGAAKRFKKTASGGFKRKRANLRHILTKKSTKRKRHLRPKGMVSKGDLGLVVACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CTR9_XENTR
Sequence: MSRGSIEIPLRDTDEVIELDFDQLPEGDEVISILKQEHTQLHIWIALGLEYYKQVKTEDFVKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKELITQATLLYTMADKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAGVRLGMGHCFVKLNKLDKARLAFGRALDLNPTCVGALVGLAVLELNNKEADSIKNGVQLLSKAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFAAASFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASDDQEKRDIAKSHLKKVTEQYPDDVEAWIELAQILEQTDIQNALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTTYNLARLYEGLCEFHESEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQNDTYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDSKNLYAANGIGAVLAHKGYVREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVLLYLARALFKCGKLQECKQILLKARHVAPNDTVLMFNVALVLQRLATLVLKDEKSNLKAVLNAVKELELAHRYFNYLSKVGDKMRFDLALAASEARQCSDLLSQAQYHVARARKQDEEEKELRAKQEQEKEILRQKLIKEQEEKRLKEIEEQKKLLEQRAQYVEKTRNLLNFTGEMETPKEKKQRGGGGGGGGRRSKKNGEFDEFVNDDSDEDLAPRKKKRKKGGGSSGSGGEQGEGGEEGEGGEKKKKKRRKRPQKGGDGSDDDEDQAPQPKKRQPKKREKPAKFERTPPSMKGKIKSKAIISSSEDDSDEDKLKIADEGHGRGSNSDSDEGPRTQAKKRIMSDSDSDNANKSGSGAGSPQKSPQSDGDSDNNAWARKRRRQDSGSDNDSAQSRRSSGGSDNESRAASRSPESQRGSDRGSDNEGSARASPNESEQEASNNEKSDRGSDDSD
What is the function of this protein?
Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II (By similarity).  PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity).
What are the official names of this protein?
RNA polymerase-associated protein CTR9 homolog, SH2 domain-binding protein 1.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: CAH7_MOUSE
Sequence: MTGHHCWGYGQDDGPSNWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELFYEACMSLSITNNGHSVQVDFNDSDDRTVVSGGPLEGPYRLKQLHFHWGKKRDMGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAAAAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKDTKAQFSCFNPKCLLPTSRHYWTYPGSLTTPPLSESVTWIVLREPIRISERQMEKFRSLLFTSEDDERIHMVDNFRPPQPLKGRVVKASFQA
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase 7, Carbonate dehydratase VII, Carbonic anhydrase VII, CA-VII.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_NEIM0
Sequence: MLNITLPDGSVRQYESPVTVAQIAASIGAGLAKAAVAGKVNGKLVDACDPITEDSSVQIITPKDQEGIEIIRHSCAHLVGHAVKQLYPNAKMVIGPVIEEGFYYDIATEKPFTPEDVAAIEARMKELIAQDYDVVKIMTPRAEAIKIFQERGEEYKLRLIDDMPEVEAMGMYHHQEYVDMCRGPHVPNTRFLKNFKLTKLAGAYWRGDSNNEMLQRIYGTAWATKDELKAYIQRIEEAEKRDHRKLGKQLDLFHLQDEAPGMVFWHPKGWALWQVIEQHMRKELNAAGYKEVKTPQIMDKTFWEKSGHWDNYKDNMFVTSSEKREYAVKPMNCPGHVQIFNNGLRSYRDLPMRLAEFGSCHRNEPSGALHGLMRVRGFVQDDAHIFCTEDQIVSEARAFNELLVRIYKQFGFHDVSVKLSLRPEKRAGSDDVWDKAEQGLREALTACGVEWGELPGEGAFYGPKIEYHVRDALGRSWQCGTLQLDFVLPERLGAEYVTENNDRARPVMLHRAILGSLERFIGILIENHAGSFPLWLAPVQLVIMNITENQADYCREVAAKLQAAGFRAELDLRNEKIGYKIRDNSQYRFPYQIVVGDKEKQENKVAVRRKAEDLGSLDLDDFIAQLQQEITDALVNH
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_METCA
Sequence: MAFTAAEKSVIVQEFQRAPGDTGSPEVQVALLTNRINYLTPHFVKHKKDFHSRRGLLRLVNQRRKLLDYLKNTDNERYRTLIERLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PROA_NITHX
Sequence: MTASLKATCASADLPVLMNGLATQARSAARVLGLASTAQKDQALDAMARAIRAAAAAILNANAEDVADARAGGATSAFVDRLTLTQARIDAMADGVKVVRAIDDPVGKVTERWQRPNGMTIERVRVPLGVVAVIFESRPNVCADAGALCLKSGNAVILRGGSDSFRSCRAIHECLVQGLREAGLPEAAITLVPTRDRAAVGLLLSGLDGGIDVIVPRGGKSLVARVEAEARVPVFAHLEGVNHVYVDGAADLAMAKAIVLNAKMRRPGVCGAAETLLVDRAGAPNTLKPLVDMLIDAGCEVRGDAAVQAVDARVKPATDDDWDTEYEDAIIAARVVDGVGEAIDHIQRHGSHHTDAIVTDDSNTAARFLDEVDSAIVLHNASTQFADGGEFGFGAEIGIATGKFHARGPVGAEQLTSFKYRVHGTGQTRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOP4_YEAS7
Sequence: MFSQIVLLLSAFIYVVSATARRGTIKGRLDLAASNITGFVSTRTSFKLYQIGNFSTEYPYTSTTMFQDDEGNFEFANLPLNDGVNETTYYVMYPASMDFNLKPNRILIEFKNLENGTLQLNAFKNFFGREYFPSKDITYPEKLQSMKVHPYITVELLHKAPIRSYLQARNVSIFSTGIVGNILNSRWKLAGVITLIALVVFPIIVEKLDPETARAIREEAKRKQREKYAAVASK
What is the function of this protein?
Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles.
What are the official names of this protein?
Protein SOP4, Suppressor of PMA1-7 protein 4.
What is the protein family that this protein belongs to?
Belongs to the SOP4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.