PharMolix/UniProtQA huggingface dataset:
Protein: S35E4_RAT
Sequence: MCRCPLEHHEVRMTSAEAIAVAGSAQEHGRPKWPPDKPQVLGQPALARVVVAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLAAAVACHWGAQRPVPHSIHRRVLLLSLTFGTSMACGNVGLSTVPLDLAQLATTTTPLFTLALSALLLGRRHHPLQFAAMGPLCLGAACSLAGELRAPPAGCGFLLVATCLRGFKSVQQSALLQEERLDAVTLLYATSLPSFCLLAGAALVLEAGAAPPLPPTDSRLWACVLLSCFLSVVYNLASFSLLALTSALTVHVLGNLTVVGNLILSRLLFGSHLSALSYVGIALTLSGMFLYHNCESVASWATRRGLWNRDQPGKGL
What is the function of this protein?
Putative transporter.
What are the official names of this protein?
Solute carrier family 35 member E4.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35E subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IPYR_THEVB
Sequence: MSIDLSRIPAQPKPGVVNVLVEIAGGSRNKYEFDKEMKVFALDRVLYSAVVYPYDYGFIPNTLADDGDPLDGLVMMDEPTFPGCVIPARPIGMLEMIDSGDRDEKILCVPVDDPRYAEVKSLKDIAPHRLEEIAEFFRTYKNLQKKVTEILGWQDVDAVQPLVEKCIKAYKG
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBT1_YEAST
Sequence: MVSYGSHSSEVSKVLKTPKFVLRYGNVSSKQRFALKRKINYKLRESKYQEYLNEYNTFVLYDWENSGAGSLVDSSYNLPSLWKEFITEGISKGAINDKLPTVFMKRKLTNSALGHCLGLDFLTDPSESEHEYRCMFQTVQDIPSLSQLILFNSMPNVPVRLKLHTIGININFGCKRSLISNGGDQDTEMSEAVSYIQPLLEESSRMYRNLNYWKLLKIARNNKKDEPLDQSTRIKSQVKLLLSQLATNRITSPSVTDHGGHNWLIFTRRRL
What is the function of this protein?
Involved in 5'-end processing of mitochondrial COB, 15S rRNA, and RPM1 transcript.  May also have a role in 3'-end processing of the COB pre-mRNA.
What are the official names of this protein?
Cytochrome b termination protein 1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DRE2_BABBO
Sequence: MAFRILAVGANREDMEKHVRFSSFLSKYSSITSSLLKLDSVLFPSVTRLELSKKDYDYMSISAVFEYGNKPCTYDHVVLATDSTFCRTGSDASPLLEKLHEALTPNGTIVIILPHSNPNENVVKKECMYTGFVELTFFEHNNFKWIVGKRPNWAPAQRSLTRGTLKVVSLDDYIPSAPAAESCDTKPRPCANCNCGRAERVNTDAKESTVNADGPTSSCGKCYLGDAFRCANCPYRGMPAFAPGDKIRLE
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: KTHY_RALSO
Sequence: MTGKFITFEGIDGAGKSTHLAWFAQQLEARLAPQGRKVVVTREPGGTPLGERLREVLLHERMHLETEALLMFASRREHIAEVIQPALERGDWVISDRFTDATFAYQGGGRGLAIERLEALEQWVQQGLQPTRTLLFDLAPEVAAARLADARTPDKFEAESAQFFVRTRAEYLRRAAAEPGRFVVIDAARARDDIRKDLEKLLASL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SYP_TRIL1
Sequence: MRYTQFFIPTLKETPSDAEVVSHQLMMRSGMIRKIAAGIYTYMPLGLRSIRKFEQIVREEMNRAGAIELLMPGVQPAELWIESKRWAQYGKELLRFKDRKDNEFCMGPTHEEIITDIARREVKSYRQMPVNFYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFDVDSSAADLSYDKMYQAYNRIFERCGLNFRAVEADTGSIGGSASHEFMVLASSGEDAIVSCNACRYAANVEKAEGVRQQQGGAGQQALTKVHTPDKKTIAEVAEFLGLPQSGTVKALVLSNGEGQFVMALVRGDHELNELKLKNRLGWDEIQMATDDEILRFTGSPPGFLGPLGLKAELQVVADYAVETMADFVIGANETDQHYTGANTGRDFQISQIADIRLIGAGDPCPRCSGGTLEVWRGIEVGHVFKLGTKYSSSMNATYLDKDGKEQIIFMGCYGIGIGRTVAASIEQNHDENGVIWPLPLAPFHCSVVAINAQKDEAVMAAAQDIHDRLEAAGVEVLLDDRDERPGVKFKDHDLIGIPLRIVVGGKNLAEGNVEFKQRAGGEMQLLAPEQAIESVIAKVRESCGGSR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_PSEMY
Sequence: MSSGRIVQIIGAVIDVEFPRDQVPNVYEALKVQGAETTLEVQQQLGDGVVRTIAMGSTEGLKRGLDVNSTGKAISVPVGKATLGRIMDVLGNPIDEAGPIGEEEQWEIHRAAPSYAEQAGGNDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKKGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPNVIGQEHYETARGVQYVLQRYKELKDIIAILGMDELSEDDKLLVARARKIQRFLSQPFFVAEVFTGAPGKYVSLKDTIAGFSGILKGDYDHLPEQAFYMVGGIDEAIEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RR15_SPIOL
Sequence: MKKNSFISVISDEKKEENKGSVEFQVFCFTNKIRRLTLHLELHKKDYSSQRGLRKTLGKRQRLLAYLLKINGVRYKELISKLNIRELKTR
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic, Chloroplastic small ribosomal subunit protein uS15c.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOY_HALH5
Sequence: MIYKIFYQKDFDQVPVRENTDSLYVEAESEADVRKKLSEKNYNLEFITPISGEFLAYEQQKEHFTVEKL
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: TSAD_THEMA
Sequence: MRVLGIETSCDETAVAVLDDGKNVVVNFTVSQIEVHQKFGGVVPEVAARHHLKNLPILLKKAFEKVPPETVDVVAATYGPGLIGALLVGLSAAKGLAISLEKPFVGVNHVEAHVQAVFLANPDLKPPLVVLMVSGGHTQLMKVDEDYSMEVLGETLDDSAGEAFDKVARLLGLGYPGGPVIDRVAKKGDPEKYSFPRPMLDDDSYNFSFAGLKTSVLYFLQREKGYKVEDVAASFQKAVVDILVEKTFRLARNLGIRKIAFVGGVAANSMLREEVRKRAERWNYEVFFPPLELCTDNALMVAKAGYEKAKRGMFSPLSLNADPNLNV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPB3_BOVIN
Sequence: MAKIILRHLIETPVRYEQEFEARGLEDCRLDHALYALPGPTTVDLGKARAAQAPPVDAAEMPPQRGESRFQVLLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGIETKDLSAILCHDGILVVEVKDSAGTK
What is the function of this protein?
Inhibitor of actin polymerization.
What are the official names of this protein?
Heat shock protein beta-3, HspB3.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock.
Protein: FRDD_SALTY
Sequence: MINPNPKRSDEPVFWGLFGAGGMWGAIIAPVIVLLVGIMLPLGLFPGDALSFERVLTFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTAIGVITL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MYL1_MOUSE
Sequence: MAPKKDVKKPAAAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQEDFKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFEQFLPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALLAGQEDSNGCINYEAFVKHIMSV
What is the function of this protein?
Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.
What are the official names of this protein?
Myosin light chain 1/3, skeletal muscle isoform, MLC1/MLC3, MLC1F/MLC3F, Myosin light chain alkali 1/2, Myosin light chain A1/A2.
Protein: GAR1_DEBHA
Sequence: MNRGRGGFRGGRGGRTGPSQFQQGPPDTVLEMGAFMQSCEGDIVCRSINVKIPYFNAPIYLENKTQVGKVDEILGPVNEVFFTIKPSEGVQADSFKDGDKFYIGPDKLLPLERFLPKPKEFGTKPKKKSAGGAGRGGFGGRGGARGGRGGFGGRGGSRGGFGDRGGRGGSRGGFGGRGGSRGGFGDRGGFGGRGGSRGGFGDRGGRGGGFRGGRF
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit GAR1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ALDH_STAAC
Sequence: MRDYTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADVDKAVEAADDVYLEFRHTSVKERQALLDKIVKEYENRKDDIVQAITDELGAPLSLSERVHYQMGLNHFVAARDALDNYEFEERRGDDLVVKEAIGVSGLITPWNFPTNQTSLKLAAAFAAGSPVVLKPSEETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGSGPTGSKIMEKAAKDFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQVCTAGTRVLVPNKIKDAFLAELKEQFSQVRVGNPREDGTQVGPIISKKQFDQVQNYINKGIEEGAELFYGGPGKPEGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYNDLDEAIQIANDTKYGLAGYVIGKDKETLHKVARSIEAGTVEINEAGRKPDLPFGGYKQSGLGREWGDYGIEEFLEVKSIAGYFK
What are the official names of this protein?
Putative aldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: ENCAP_BRELN
Sequence: MNNLYRELAPIPGPAWAEIEEEARRTFKRNIAGRRIVDVAGPTGFETSAVTTGHIRDVQSETSGLQVKQRIVQEYIELRTPFTVTRQAIDDVARGSGDSDWQPVKDAATTIAMAEDRAILHGLDAAGIGGIVPGSSNAAVAIPDAVEDFADAVAQALSVLRTVGVDGPYSLLLSSAEYTKVSESTDHGYPIREHLSRQLGAGEIIWAPALEGALLVSTRGGDYELHLGQDLSIGYYSHDSETVELYLQETFGFLALTDESSVPLSL
What is the function of this protein?
Shell component of a type 1 encapsulin nanocompartment.  Assembles into proteinaceous shells 23-24 nm in diameter with 2-2. 5 nm thick walls.  Cargo protein DyP (dye-decolorizing peroxidase) is targeted to the interior via its C-terminal extension; probably only 1 DyP hexamer is incorporated into each shell.  Empty shells can be isolated in the absence of cargo.
What are the official names of this protein?
Type 1 encapsulin shell protein, Linocin M18, M18 encapsulin.
What is the protein family that this protein belongs to?
Belongs to the encapsulin family. Family 1 subfamily.
What are the subcellular locations of this protein?
Encapsulin nanocompartment.
Protein: RSMH_CLAMS
Sequence: MALDDIHTPVLLERCLELLAPALQGEGAVLVDATLGMAGHSEAFLDALPGLRLVGLDRDPDALAIAGERLARFGDRVHLVHTVYDGIGRALDGLGIGEVQGVFFDLGVSSLQLDRVERGFSYSQDAPLDMRMDGTAGLTAAQVVAEYDELELRRIFYDYGEEKLAPRYASRIVQAREVEPITTSARLVEIIQQATPAAVQRAGHPAKRVFQALRIEVNQELSVLARAMPAAIDRLAVGGRVVVESYQSLEDRIVKRELRVRSTSTAPVGLPVELPEHRPELKLLVRGAELADQHEIAQNPRAASVRLRAAERARRRHA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPLJ_ARATH
Sequence: MRSPHAFRNGESPTLRDHTHFHSTVTAQKLRRFNSLILLLRLASFSFSLASAVFMLTNSRGSASPHWYDFDAFRFVFVANAIVALYSVFEMGTCVWEFSRETTLWPEAFQVWFDFGHDQVFSYLLLSAGSAAAALARTMRGGDTCTANKAFCLQSDVAIGLGFAAFLFLAFSSCFSGFRVACFLITGSRFHLYS
What are the official names of this protein?
CASP-like protein 4C1, AtCASPL4C1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPG1_YEAST
Sequence: MFYLSDIEEEASAGAEPTYNFWEVLLFSNTQENLVTVVGELHTLTDRVVHYKIEPESREVTATTLPSLLALLLEKRNQARRLYRDVLSMKMSELDWDIDDLFTQLQEELTRTDDTLSMYPRRRFYH
What is the function of this protein?
Gamma subunit of a guanine nucleotide-binding protein (G protein).  G proteins are involved as modulators or transducers in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.  Involved in the determination of the cAMP level according to nutritional conditions, most probably as a regulator of cAMP phosphodiesterase.  Required for the control of pseudohyphal and haploid invasive growth.
What are the official names of this protein?
Heterotrimeric G protein gamma subunit GPG1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCZ1_ASHGO
Sequence: MDFIAVYNPAVYAKEADSEAWRQLLLYHSFKEDAEEPTPQNEKLSLIGMIQGIWQFAHNFSEPETRGSVRYVDTQLERRRVIAVEVEDGHFMAFGVEDGKRYGCEYYVRELLQSYHVFRLHCGSMSEFADRGELTDRLNEHVVGYWQALKLVPEAIYASTLASVCWHDGYKVSELELRDRAWESYIKNEILLDSESFLGLKDMCIYKLPRDGRRSAAEYGLLRSFAPEFLSLPELSNWVYHLDRLFETALSSHVLAGHVRLSIGGDEQEEEGELRHDSQPASDVGARMWRNVTMPISMTYDTMSEVGNLTGINTLMSGLNSLTSGFSSMTSRLVRRADRQNSDTASLSLHVDHGFLISPLALEALPESYRYRRFQLRFSTDEPQWYRLLFWYYKDYLCIFIFHENFDKIWDPDYLQAIDAKLYDAMLQLEGSVVTEDNKPGRFAYGVFNKTTKRIECSLPLLRFSDKRSDEKSRQPLKMVVAGIDETLQFLTAGTFATNMATSRTNDEHMGPSATNTLRMPEPTDAPSSSWTLDITKLNLFQGLNENLRLEKMADTDSGTFLDSLSSEKLLQLNVELCRLYTGIRRSEYNKAGIQEEQLLRLNNGILFYISTSPTEDVLILKNWFMDDKYTKAENKRSTSASLLHSLGGDVRRWWNARTNREQ
What is the function of this protein?
In complex with MON1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.  The CCZ1-MON1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking.
What are the official names of this protein?
Vacuolar fusion protein CCZ1.
What is the protein family that this protein belongs to?
Belongs to the CCZ1 family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: PROA_STRZP
Sequence: MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEILAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLENGLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTALKKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPVIETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQMLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVSHIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQKLHARGPMGLKELTSYKYVVTGDGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_PROMA
Sequence: MHTINSDLRNTDPDISFLINQELLRQQTHLELIASENFASEAVMEAQGSVLTNKYAEGLPNKRYYGGCEHIDAIEQLAITRAQTLFNAEWANVQPHSGAQANFAVFLALLNPGDTIMGMDLSHGGHLTHGSPVNVSGKWFNAIHYGVDQTTKVLNFEQIRQVALKNRPKLIICGFSAYPRTIDFKAFRSIADEIDAYLLADIAHIAGLVACGAHPNPVPYCDVVTTTTHKTLRGPRGGLILCRDKEFGKRFDKAVFPGNQGGPLEHVIAAKAVAFGEALKPEFKTYTFQVISNAKALAKRIQERGISIVSEGTDNHIVLLDLRSIEMTGKKADSLISEVNITANKNTVPFDPESPFVTSGLRLGTAALTTRGFTEKAFIEVADVIADCLLNPEDLSIKEQCKAKVIDLCNRFPLYNSNQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABV_SHELP
Sequence: MIIKPKTRGFICTTTHPVGCEANVLEQINITKAKGPVANGPKKVLVIGSSSGYGLSSRIAAAFGSGAATLGVFFEKPGTETKPGTAGWYNSAAFDKFAKQGGLYSKSLNCDAFSHEAKQKAIELIKQDLGQVDMVVYSLASPVRKLPDSGELIRSSLKPIGETYKSTAVDTNKDLIIETSVEPATEQEIEDTVTVMGGQDWELWINALAEAGVLTPDCKTVAYSYIGTELTWPIYWHGALGKAKMDLDRAAHALNDKLSATGGSANVAVLKSVVTQASSAIPVMPLYIAMVFKKMREEGLHEGCQEQINRMFHERLYRADGAAPAVDDANRLRLDDWELRDEIQQHCRDLWPTITTENLSELTDYREYKEEFLKLFGFGIESVDYDADVNPEVNFDVEQF
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: SMG_COXBR
Sequence: MKDESVLNVLMYLFKNHMQENCTLDLGEKKLLVQLEELGFHRTVIDQALSWLNNLSYSGREPMQLPQKNSFRVFSDYECDLLDTECRRFLITLEQQAILNPHTRELVINQALELSCEGIDVSLLKWVTLMVLFNQSSEKEALASMELLVLDDTVGGIH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: SYQ_ECO5E
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRSDFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOXK_CYBSA
Sequence: MKVSLVYGLTCFLDATSSALPSAMAAANSESSALEKRNDGYLVMCKNCDPNSGSCDWKQNWNTCVGIGSNVHWMVTGESNGQQGCAIIWEGSGCTGRSTTMCCPGDTCCNINTGFYIRSYRRVE
What is the function of this protein?
This toxin kills sensitive strains of yeast.
What are the official names of this protein?
Killer toxin.
What are the subcellular locations of this protein?
Secreted.
Protein: ACYP_POLNA
Sequence: MQSDKDKTFDSWLVKAIGRVQGVGYRDACIRYARAQDITGWVRNRVDGSVELMLQGSKEQLADMCRWLRDGIPAAHVEKLEVSKVPPPSPRLNRFDRLPNL
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: GUAA_ALCBS
Sequence: MTDIHAQRILILDFGSQYTQLIARRVREIGVYCEIRAFDMTAEELAEFAPKGIILSGGPESVTAAQTPRAPQAVFEAGIPVLGICYGMQTMAEQLGGKVIAGEKHEFGYARVEKAEPNALLDGIVDHEEQGKEFLDVWMSHGDRVGEMPAGFVATATTGSCPIAGMANDEKRFYGIQFHPEVTHTLQGGRLLERFIRELCECEALWTPSNIISDAIDTIREQVGTDEVILGLSGGVDSSVVAALLHKAIGDQLTCVFVDNGLLRHQEGDQVMEMFADNMGVKVIRVDAEDNFLGKLAGEADPEKKRKIIGNTFIDIFDDEASKLQNANWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPEDMKLKLVEPLRELFKDEVRKIGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADTLRLADHIFIEELRAAGLYHKTSQAFAVFLPVKSVGVVGDARRYEYVVALRAVETIDFMTARWAHLPYDFLELVSSRIINEIPGISRVTYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL10_STREM
Sequence: MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRRSLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAKTAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAESKEGAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL3_SALAI
Sequence: MDRQVKGILGAKLGMTQVWDNNRVVPVTVVQAGPCVVSQVRSHQKDGYAAVQLAYGAIDPRKVKKPISGHYTKADVAPRRHIVELRTTDAAEYSLGQEVTVEQFPAGISVDVTGKTKGKGYAGPMKRHGFHGLRASHGVERKHRSPGSIGGCATPGRVFKGTRMAGRMGGVRYTVQNLTVQAVDTENNLLLVRGAIPGPKGALVLVRTAAKAKKGGAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.