PharMolix/UniProtQA huggingface dataset:
Protein: LSRR_SALTI
Sequence: MSDNTLVSDYGMCEEEQVARIAWFYYHDGLTQSEISERLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYENALRNHFALQNIRVLPALPDADIGLRLGIGAAHMLMESLRPQQLLAVGFGEATMTTLKRLSGFISAQQIRLVTLSGGVGPYMTGIGQLDAACSVSIMPAPLRASSQEIACTLRNENSVRDVMLTAQAADAAIVGIGAINQKDQASILKSGYITQGEQLMIGRKGAVGDILGYFFDAHGEIIPDIKIHNELIGLKLNSLSTIPTVIGVAGGEQKAEAIIAAMRGNYINALVTDQKTAGKIIQLIEK
What is the function of this protein?
In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription.  In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes (By similarity).
What are the official names of this protein?
Transcriptional regulator LsrR.
What is the protein family that this protein belongs to?
Belongs to the SorC transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_YERPY
Sequence: MACLTLALDAMGGDFGPCVTVPASLQALASNPQLKLLLVGNPDTITPLLANADSLLLERLQVIPAEHVIASDAKPSQAIRASRGTSMRVALELVKNGEAAACVSAGNTGALMGLAKMMIKPLEGIARPALMTVIPNQRRSKTVVLDLGANVECDSTMLVQFAVMGSVMAEEVVGIVEPRVALLNIGEEENKGLDNIREAAAVLKNTPAINYIGYLEGNDLLTGKTDVMVCDGFVGNVTLKTMEGVIRMFLSLLKPSGEGSKQSWWLKLIGRWLQKRVAKRFGHLNPDQYNGACLLGLRGIVIKSHGAANQRAFAVAIEQAVQAVQRQVPERIAARLEAVLPKSD
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: NS1_I66A0
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIGTATRAGKQIVERILEEESDEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQTVAGSLCIRMDQAIMDKNIILKANFSVTFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGGLIGGLEWNDNTVRVSETLQRFAWRSSNEDGRPPLPPKQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: OPN4_HUMAN
Sequence: MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKGLIPSQDPRM
What is the function of this protein?
Photoreceptor that binds cis-retinaldehydes (PubMed:15674244).  Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light (By similarity).  May be involved in the optokinetic visual tracking response (By similarity).  May be involved in the regulation of retinal hyaloid vessel growth and regression (By similarity).
What are the official names of this protein?
Melanopsin, Opsin-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendrite. Perikaryon.
Protein: SEC13_CAEBR
Sequence: MTTIRQRIDTQHRDAIHDAQLNIYGNRLATCGSDRLVKIFEVRPNGQSYPLIELSGHNGPVWKVSWAHPKYGGLLASASYDKKVIIWQEVNGRWQKTYEWETHEASVTSVAFAPHQFGLMLASSSADGTIGILRFDAQTQQWQSSRIQNCHDQGVNSVSWAPGTADPAGKKRFVSAGNDKLVKIWLLNEELNEWTCEKAIHCHKDFVREAAWCPVTNKGQHSIVSCGLDGNLVLYRIADIETAEWKSKLLEQAPCALYHASFSPCGSFLSVSGDDNMITLWRENLQGQWIKIPRENKEREGMGQQR
What is the function of this protein?
As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway.
What are the official names of this protein?
Protein SEC13 homolog, CeSEH13R, GATOR complex protein SEC13, Nuclear pore complex protein 20.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Lysosome membrane.
Protein: CHL1_SCLS1
Sequence: MDLTDDSPDGEVKIHKKDFHHPYTPYPIQEKFMQTVYDVLEQGKIGILESPTGTGKSLSLICGSLTWLRDFKRKEFEGILNDGFENSEEPEWMIEAAKVRKKRELIGRREEMERKLGRIRERERCERDRMSGNGNGNMRGGKRRKVGGDGEGDLVGGSNGSNEDEFLLEDWESDGEIGGSGKKKTGDEAIFSKETLELKKSIGMWKFPSPMPLEEFPSKTTEKDKDNLHEHLRHLPLGSRKNLCINPKVNKLNSVTAINERCAELQQSSTPKEHKCPHLPNKDNKPLVSTFRDHALATIRDIEDMGALGKEISICPYYASRSAIKPAEIVTLPYPLLLQKSAREALGISLKGHVVIIDEAHNLMDAIAGIYGTEMSLKELKLAKEMLGNYFMKFAKRLKGKNRIYVAQAIRVVDSLMGYLMKRLEGTEIDGVVDQKELLAGKGADQIDLFKLIRYLQESKLARKVESYTEHTRNIKQASTIPHNNKETPKSTTPILHTLTSLLLALTHPTTEGQLFFLKSTSTSPSPSPDLITLKFQLLNPAPHFESIVSSARAIILAGGTMSPFSDYTSILFPSIPSHKITTLSCGHVIPKTHLFASTVSRGPTGIPFKWTFANRGNTDMMDELGRVLLNVCTIVPDGVVVFFPSYNFLSTILYRFSIPSSGTGSATATATGTEKGKGKTILERLSEKKPIFQESKEESVETILAAYAKSIAEGKGALLFSVVGGKLSEGINFSDALGRCVMIVGLPFPNMHTAEWKRRLRFIEESAVERLTSFYQEKESNNKDGNGNEEEGNGKKKENREKIQRDQILQQAKGEARDYFENVCMRAVNQCVGRAIRHRGDWAGILLLDERYKGERVVGKLAGWIREGVLRGEGMGMGDAGGFGRLMGGLGRFCRGRREVL
What is the function of this protein?
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity).  May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).  Has a specific role in chromosome segregation during meiosis II (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase CHL1, Chromosome loss protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HCHA_ECOHS
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNL3_HUMAN
Sequence: MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV
What is the function of this protein?
May be required to maintain the proliferative capacity of stem cells.  Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein-like 3, E2-induced gene 3 protein, Novel nucleolar protein 47, NNP47, Nucleolar GTP-binding protein 3, Nucleostemin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus.
Protein: UVRC_STRPG
Sequence: MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCFYYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIDNLGHLLGINKPVRIEAFDNSNIQGTSPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHPL3_HUMAN
Sequence: MPGAAAAAAAAAAAMLPAQEAAKLYHTNYVRNSRAIGVLWAIFTICFAIVNVVCFIQPYWIGDGVDTPQAGYFGLFHYCIGNGFSRELTCRGSFTDFSTLPSGAFKAASFFIGLSMMLIIACIICFTLFFFCNTATVYKICAWMQLTSAACLVLGCMIFPDGWDSDEVKRMCGEKTDKYTLGACSVRWAYILAIIGILDALILSFLAFVLGNRQDSLMAEELKAENKVLLSQYSLE
What are the official names of this protein?
LHFPL tetraspan subfamily member 3 protein, Lipoma HMGIC fusion partner-like 3 protein.
What is the protein family that this protein belongs to?
Belongs to the LHFP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRPC_THEMA
Sequence: MRRLWEIVEAKKKDILEIDGENLIVQRRNHRFLEVLSGKERVKIIAEFKKASPSAGDINADASLEDFIRMYDELADAISILTEKHYFKGDPAFVRAARNLTCRPILAKDFYIDTVQVKLASSVGADAILIIARILTAEQIKEIYEAAEELGMDSLVEVHSREDLEKVFSVIRPKIIGINTRDLDTFEIKKNVLWELLPLVPDDTVVVAESGIKDPRELKDLRGKVNAVLVGTSIMKAENPRRFLEEMRAWSE
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ATPE_STRPD
Sequence: MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAPLQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLRAEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS13_THEP3
Sequence: MARIAGVDLPRDKRVEIALTYIYGIGRSRSNEILAKAGVNPDTRVKDLTEEEVSRLREIIDKEYKVEGDLRKEVAMNIKRLMDIGCYRGIRHKRGLPVRGQRTRTNARTRKGPRKTVAKKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RK32_ADICA
Sequence: MAVPKKRTSASMKKIRNHSWKIKSVEKSLKSFSLAQSVLSGRSKSFYYGTEKKPFQKN
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EPT1_YEAST
Sequence: MGYFVPDSHIENLKSYKYQSEDRSLVSKYFLKPFWQRFCHIFPTWMAPNIITLSGFAFIVINVLTVFYYDPNLNTDTPRWTYFSYALGVFLYQTFDGCDGVHARRINQSGPLGELFDHSIDAINSTLSIFIFASETGMGFSYNLMLSQFAMLTNFYLSTWEEYHTHTLYLSEFSGPVEGILIVCVSLILTGIYGKQVIWHTYLFTITVGDKVIDVDTLDIVFSLAVFGLVMNALSAKRNVDKYYRNSTSSANNITQIEQDSAIKGLLPFFAYYASIALLVWMQPSFITLSFILSVGFTGAFTVGRIIVCHLTKQSFPMFNAPMLIPLCQIVLYKICLSLWGIESNKIVFALSWLGFGLSLGVHIMFMNDIIHEFTEYLDVYALSIKRSKLT
What is the function of this protein?
Catalyzes the final step in the CDP-ethanolamine route leading to phosphatidylethanolamine (PE).  Can also catalyze the formation of phosphatidylcholine (PC) from CDP-choline, but does not substantially contribute to PC biosynthesis.  Preferentially uses CDP-dimethylethanolamine and CDP-propanolamine as aminoalcohol substrates.  Shows highest activity toward di-unsaturated diacylglycerol species as lipid substrates.  The CDP-ethanolamine pathway may play a role in maintaining the proper PE species distribution.
What are the official names of this protein?
Choline/ethanolaminephosphotransferase 1, ETHPT, Ethanolaminephosphotransferase 1, Aminoalcohol phosphotransferase EPT1.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: JOSL_ARATH
Sequence: MADSESKIYHERQRLQFCLLHCLNNLFQDKDAFTKESLNSIAEKLETNDPNKETWTPLSFVLKPHHNTITGNYDVNVMITALEGKGKSVVWHDKRIGASSIDLDDADTLMGIVLNVPVKRYGGLWRSRHWVVVRKINGVWYNLDSDLVVPQLFRDDDEVRGFLDQNLSLDVIGLIWNLPYNANQLPLASNYRVVITHWSDLNGMFSHVTNYPLDFDVYPQVSSKVSAIYKATGTKRFNANTRPVTPGKQSSVKGPYYKNPGCTTSCGLRLPRKTECTAARLIKDLSCKFVMGLRLVVMRKKKKKRSPPLKKASSSGISQPSVISVVNDNNHRSAAIEDCIQFINSSSSFTRSNSTCGSKS
What is the function of this protein?
May act as a deubiquitinating enzyme.
What are the official names of this protein?
Josephin-like protein.
Protein: DSRB_SHIF8
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVALEDYPLGIWFFNEAGHQDGIFVEKAE
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: MUTL_CHLTR
Sequence: MSLSPSRIRLLDSVTVNQISAGEVIENAASVVKELIENSLDAGADEIHIETLGGGRGQIVVRDNGVGMDPEEVPVALQRHATSKIAHFADIFSLASYGFRGEALPSIASISKMEIHTARAGGLGSKTLIEKGEPVCCEPAPRQQGTTIAVHSLFYNVPMRQSFQKSPQMDRLAIRRLLENSVLSSEGIGWTWISECRQELYVAKKQGFIERVALVLGESFVQEAFFIDKQQGDLRVLGFLGSPNQHRSTRQGQRLFINNRAVESSFISKKVAEAYAWMIPAQRYPIFVLKLFLPPMWCDFNVHPQKTEVRLLQEGQISNLLVEAISEALLRRSPSLEETVLKVPTEKIPIENEGISVPSIRPAIVSAPLSCPTFSQQPYLKTEMATIVSRDSASSSLSVVEKVRFLTSLGKVLLVEDSEGVHVVFVQAARKHLFYVSLLSERLESRLACQTFLLPSSVQMTKLEADFLQMRLEALTALGIELSRISPDSFAIESAPPFIQEEELKEWIVALAQEGALHVGESFEQLVENTVQKLVFSRNARAFDYAWLDILWKLGKPEKAFDGEMIRRLVLDDDFM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ACSA1_NOVHA
Sequence: MPEVRSSTQSESGMSQWMGKILSIRGAGLIIGVFGLCALIAATSVTLPPEQQLIVAFVCVVIFFIVGHKPSRRSQIFLEVLSGLVSLRYLTWRLTETLSFDTWLQGLLGTMLLVAELYALMMLFLSYFQTIAPLHRAPLPLPPNPDEWPTVDIFVPTYNEELSIVRLTVLGSLGIDWPPEKVRVHILDDGRRPEFAAFAAECGANYIARPTNEHAKAGNLNYAIGHTDGDYILIFDCDHVPTRAFLQLTMGWMVEDPKIALMQTPHHFYSPDPFQRNLSAGYRTPPEGNLFYGVVQDGNDFWDATFFCGSCAILRRTAIEQIGGFATQTVTEDAHTALKMQRLGWSTAYLRIPLAGGLATERLILHIGQRVRWARGMLQIFRIDNPLFGRGLSWGQRLCYLSAMTSFLFAVPRVIFLSSPLAFLFFGQNIIAASPLALLAYAIPHMFHAVGTASKINKGWRYSFWSEVYETTMALFLVRVTIVTLLSPSRGKFNVTDKGGLLEKGYFDLGAVYPNIILGLIMFGGLARGVYELSFGHLDQIAERAYLLNSAWAMLSLIIILAAIAVGRETQQKRNSHRIPATIPVEVANADGSIIVTGVTEDLSMGGAAVKMSWPAKLSGPTPVYIRTVLDGEELILPARIIRAGNGRGIFIWTIDNLQQEFSVIRLVFGRADAWVDWGNYKADRPLLSLMDMVLSVKGLFRSSGDIVHRSSPTKPSAGNALSDDTNNPSRKERVLKGTVKMVSLLALLTFASSAQAASAPRAVAAKAPAHQPEASDLPPLPALLPATSGAAQAGSGDAGADGPGSPTGQPLAADSADALVENAENTSDTATVHNYTLKDLGAAGSITMRGLAPLQGIEFGIPSDQLVTSARLVLSGSMSPNLRPETNSVTMTLNEQYIGTLRPDPAHPTFGPMSFEINPIFFVSGNRLNFNFASGSKGCSDITNDTLWATISQNSQLQITTIALPPRRLLSRLPQPFYDKNVRQHVTVPMVLAQTYDPQILKSAGILASWFGKQTDFLGVTFPVSSTIPQSGNAILIGVADELPTSFGRPQVNGPAVLELPNPSDANATILVVTGRDRDEVITASKGIAFASAPLPTDSHMDVAPVDIAPRKPNDAPSFIAMDHPVRFGDLVTASKLQGTGFTSGVLSVPFRIPPDLYTWRNRPYKMQVRFRSPAGEAKDVEKSRLDVGINEVYLHSYPLRETHGLIGAVLQGVGLARPASGMQVHDLDVPPWTVFGQDQLNFYFDAMPLARGICQSGAANNAFHLGLDPDSTIDFSRAHHIAQMPNLAYMATVGFPFTTYADLSQTAVVLPEHPNAATVGAYLDLMGFMGAATWYPVAGVDIVSADHVSDVADRNLLVISTLATSGEIAPLLSRSSYEVADGHLRTVSHASALDNAIKAVDDPLTAFRDRDSKPQDVDTPLTGGVGAMIEAESPLTAGRTVLALLSSDGAGLNNLLQMLGERKKQANIQGDLVVAHGEDLSSYRTSPVYTIGTLPLWLWPDWYMHNRPVRVLLVGLLGCILIVSVLARALARHAARRFKQLEDERRKS
What is the function of this protein?
Bifunctional protein comprised of a catalytic subunit and a regulatory subunit.  The catalytic subunit of cellulose synthase polymerizes uridine 5'-diphosphate glucose to cellulose in a processive way.  The thick cellulosic mats generated by this enzyme probably provide a specialized protective environment to the bacterium.  The regulatory subunit binds bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
What are the official names of this protein?
Cellulose synthase 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AcsB/BcsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VSX1_HUMAN
Sequence: MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAVAPCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLNSAEGGLLGSCAPWLLGMHKKSMGMIRKPGSEDKLAGLWGSDHFKEGSSQSESGSQRGSDKVSPENGLEDVAIDLSSSARQETKKVHPGAGAQGGSNSTALEGPQPGKVGAT
What is the function of this protein?
Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster (PubMed:10903837).  May regulate the activity of the LCR and the cone opsin genes at earlier stages of development (PubMed:10903837).  Dispensable in early retinal development (By similarity).
What are the official names of this protein?
Visual system homeobox 1, Homeodomain protein RINX, Retinal inner nuclear layer homeobox protein, Transcription factor VSX1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROB_SYNP2
Sequence: MPQTIVVKIGTSSLTDPKTGMLALATIGTLVETLTRLKQKGHRVILVSSGAVGVGCGVLKRSERPKKIAEKQAIAAVGQGRLIRLYDDLFTSLQQAIAQVLLTRRDLVDRTSYLTVQEALNAMLDLSVIPIVNENDTVAVDELKFGDNDTLSALVASLVNADWLVLLTDVDRLYSADPRQNPDARPIPLVSSSELFNLQVDAGSSGSQWGTGGMQTKLTAARIATSAGVRTVITQGKTPQNLLKIVAGEDIGTHFEAQPQADNARKRWIAYGLVPQGILTLDDGATQALLKNGRSLLAAGIVAVEGEFTINDPVELRTQTGQAIARGLVNYNHQDIEKIQGQHSTQIRQILGYGSADTVIHRDNLALLIAAEGI
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CYPCA
Sequence: MASLRKTHPLIKIANDALVDLPTPSNISAWWNFGSLLGLCLITQILTGLFLAMHYTSDISTAFSSVTHICRDVNYGWLIRNVHANGASFFFICIYMHIARGLYYGSYLYKETWNIGVVLLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYMGDMLVQWIWGGFSVDNATLTRFFAFHFLLPFVIAAATIIHLLFLHETGSNNPIGLNSDADKVSFHPYFSYKDLLGFVIMLLALTLLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLMVVPLLHTSKQRGLTFRPITQFLFWTLVADMIILTWIGGMPVEHPFIIIGQIASVLYFALFLIFMPLAGWLENKALKWAC
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VAM10_YEAST
Sequence: MLFEVFGEVLASYIVSSKTKGELAFPVNNAPPDSLVAINCVVLFLRSAIGSCSGAKELIRSSALELSCSSSCGLPATDKPGSFHSGALSKSILSANEAVVSKSSLSFLSSFVDI
What is the function of this protein?
Required for vacuolar fusion.  Involved in the early steps of the fusion pathway.
What are the official names of this protein?
Vacuolar morphogenesis protein 10.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: RL19_BORBU
Sequence: MDLIRKIEAQNKKNEAFVFNVGDTVRVVYKIIEGSNERLQSFEGIVISFQNKGIGKTFLIRKISSGIGVEKIFPVYSPIIEKVEVLRRGKVRRAKLYYMRNRIGKAAMKIKERLTIKKVKH
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.