PharMolix/UniProtQA huggingface dataset:
Protein: ARX_DANRE
Sequence: MSSQYDDDSRDRSECKSKSPTVLSSYCIDSILGRRSPCKVRQLGAQSLPAPVRPDHEMTTEVTSKENSFDSDMHLPPKLRRLYGPGGKYLDSGRGFHEHLEKGERERLLDQACESLKISQAPQVSISRSKSYRENAPFSQSDEGQSPEHMAQELVELSTLKFEEDVVKEEACGDNSLSPKDEESLHNDGDVKDGEDSVCLSAGSDSEEGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGVQAHPTGLPFPGPLAAAHPLSHYLEGGPFPPHPHPALESAWTAAAAAAAAFPGLAPPPNSSALPPATPLGLGTFLGTAMFRHPAFIGPTFGRLFSSMGPLTSASTAAALLRQTAPPVESPVQPSAALPEPPSSSSSTAADRRASSIAALRLKAKEHSAQLTQLNILPSGTAGKEVC
What is the function of this protein?
Transcription factor (By similarity).  Appears to be indispensable for the central nervous system development.  May have a role in the neuronal differentiation of the ganglionic eminence and ventral thalamus.  May also be involved in axonal guidance in the floor plate.
What are the official names of this protein?
Aristaless-related homeobox protein, ARX.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL112_ARATH
Sequence: MASEKKLSNPMRDIKVQKLVLNISVGESGDRLTRASKVLEQLSGQTPVFSKARYTVRSFGIRRNEKIACYVTVRGEKAMQLLESGLKVKEYELLRRNFSDTGCFGFGIQEHIDLGIKYDPSTGIYGMDFYVVLERPGYRVARRRRCKTRVGIQHRVTKDDAMKWFQVKYEGVILNKSQNITG
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11-2, L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: BURPE_ORYSJ
Sequence: MAPPRHARLVAATIAVLLCHLPRSAASPSWSDAAVSPPSPSPQLCPMMQQRSVLPPRVSELPASPFTAKAAFVRYWNRKVHSNRPHPAFFFAKLSPLSAPDAAAFSTLAAAGQLGSRIRAFCAAASLLCPTTPGSSWSKSSSDGDGAAAAAAPAGGGGGGGGGGDGGAAPFKNYENGNFSSYGNSGGGGADQFAVYSSGQSNGGGGGGGGVDSFRRYGKGSQGRNDSFTSYEAGGNVGTSSFTSYNGDATGGAGGFSSYAGDANTVAVSFGNYDHTGNGRSREFSEYTQDANTGEESFAAYGKTANGAAESFRTYGNHSNSIATGFDNYGDRANGAADAFSSYGASGNTPENTFKSYASGSNAGVDDFKGYRDDANVGNDSFTSYASNANGAAAGFESYGKSVNPGSVTFKGYGLGSNPNHRIGFARYSGDNTTFKAYSNDGVEFKEYQNMSKMEVSKIEAAARRPPLRWSPEPGKFFRERDLVAGNRMPMPDIADRTPPRAFLPRDIAAKIPFDAAAVSALFGAAPGTAMRQVVSSTVAECARPPSRGETKRCATSAEDVVDFAVEMLGDNVVARATESTAGGGGDVRLGRVAGVPAGGNVTRSVSCHQSLFPYLVYYCHSVPTVRVYEADILAVDSNQKINHGVAICHLDTSDWSPNHGAFIALGGKPGEMEVCHWIFQGDMTWTVAN
What are the official names of this protein?
BURP domain-containing protein 14, OsBURP14.
Protein: SAHH_LEPBJ
Sequence: MSATTQEKGLNYKVKDLSQAEWGRQEIILAEKEMPGLMALRQEYKGKKPLAGARIAGSLHMTIQTAVLIETLTELGAEVRWSSCNIFSTQDHAAAAIAKAGVPVFAWKGETEEEYWWCIEQTLFFGDKGPNMILDDGGDLTAYVHEKYPKLLSEIRGISEETTTGVKSLYKLLKKGELKVPAFNVNDSVTKSKFDNLYGCRESLADGIKRATDVMLAGKVALVCGFGDVGKGSAASLRNFGARVIVTEIDPICALQASMEGYQVLRVEDIIEQVDIVVTATGNDDIITLEHMKAMKDGAILCNIGHFDTEIQMSRLNSEKGVTKKEIKPQVDKYTFPDGKSIVVLAEGRLVNLGCATGHPSFVMSCSFTNQVLAQIELYNNKYELGVYTLPKHLDEKVAALHLEQLGVRLTKLNQKQADYLGVPLNGPFKPENYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_PELPD
Sequence: MESSAKLTSVRLSPRKTRLVVDLVRGKVIQEALNTLRFLPQPSAKLVSKLLQSAVANAEQKGVSDVDALYVKTIYVDGGSVLKRFLPRAMGRASKIRKPTSHISVTLSDSK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ARI3A_HUMAN
Sequence: MKLQAVMETLLQRQQRARQELEARQQLPPDPPAAPPGRARAAPDEDREPESARMQRAQMAALAAMRAAAAGLGHPASPGGSEDGPPGSEEEDAAREGTPGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEMEEDLGEDEEEEEEDYEDEEEEEDEEGLGPPGPASLGTTALFPRKAQPPQAFRGDGVPRVLGGQERPGPGPAHPGGAAHVAPQLQPPDHGDWTYEEQFKQLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMSIRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP
What is the function of this protein?
Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.
What are the official names of this protein?
AT-rich interactive domain-containing protein 3A, ARID domain-containing protein 3A, B-cell regulator of IgH transcription, Bright, Dead ringer-like protein 1, E2F-binding protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm.
Protein: RS12_METLZ
Sequence: MGQGKFAARNLVRTAKKFRWSDSVYSRRALKLKLKADPLEGAPIGRAIVLEKVGVEAKQPNSAIRKCVRVQLIKNGRQVTAFAVGDGAINFIDEHDEVTICGIGGRAGRSMGDIPGVRFVVSGVNGVSLNELVIGRAEKARR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PAT_SALCH
Sequence: MNRLPSSASALACSAHALNLIEKRTLNHEEMKALNREVIDYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSIFRRPFMPLLPGFRHVPFGNIDAMSMAFSEGKKTGDEIAAVILEPIQGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDTLLDGFRQLAREYPNLVHDARGKGMLMAIEFVDNETGYRFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIELCEQVLKSARNALAAMQVSVEEV
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: P5F1B_HUMAN
Sequence: MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
What is the function of this protein?
Shows weak transcriptional activator activity.
What are the official names of this protein?
Putative POU domain, class 5, transcription factor 1B, Oct4-pg1, Octamer-binding protein 3-like, Octamer-binding transcription factor 3-like.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUD_CAMJ8
Sequence: MNLEEENTIFKPLYSLKHSPINAYFSKNSDDFVVRERPLYEFSGKGEHLILHINKKDLTTNEALKILSETSGVKIRDFGYAGLKDKQGSTFQYLSMPKKFESFLSNFSHPKLKILEIFTHENKLRIGHLKGNTFFIRLKKVLPSDALKLEQALMNLDKQGFANYFGYQRFGKFGDNYKEGFEILRGKKMKNVKMKEFLISAFQSELFNRYLSKRVELSHFANDFSEKELIQIYKISKEEAKELKKQEQFFKLLKGEVLGHYPFGKCFLCEDLSAELERFKARDISAMGLLIGAKAYETGEGLALNLENEIFKDALEFKAKMQGSRRFMWGYLEELKWRYDEEKAHFCIEFFLQKGSYATVVLEEILHKNLFE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: NRDR_MICAN
Sequence: MQCPHCQHTDSRVLESRSSENGQSIRRRRECLQCKYRFTTYERIEFVPITVIKKDGKRESFDRCKLLRGIVRACEKTGIPPSRLEAIVNDIESRLQQDSKREVTSQEIGQLVLEYLRQESEVAYVRFASVYGNFQGIRDFIAALALLQSSEIERAHPSWSQVEEASVITSS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CXCR4_MACFA
Sequence: MEGISIYTSDNYTEEMGSGDYDSIKEPCFREENAHFNRIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQKPRKLLAEKVVYVGVWIPALLLTIPDFIFASVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
What is the function of this protein?
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation.  Involved in the AKT signaling cascade (By similarity).  Plays a role in regulation of cell migration, e. g.  during wound healing.  Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels.  Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity).  Involved in hematopoiesis and in cardiac ventricular septum formation.  Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells.  Involved in cerebellar development.  In the CNS, could mediate hippocampal-neuron survival (By similarity).
What are the official names of this protein?
C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Fusin, Leukocyte-derived seven transmembrane domain receptor, LESTR, Stromal cell-derived factor 1 receptor, SDF-1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction. Early endosome. Late endosome. Lysosome. Note=In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated (By similarity). In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation cluster (SMAC) (By similarity).
Protein: ALR1_SALTY
Sequence: MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITQPILLLEGFFDAADLPTISAQCLHTAVHNQEQLAALEAVELAEPVTVWMKLDTGMHRLGVRPEEAEAFYQRLTHCKNVRQPVNIVSHFARADEPECGATEHQLDIFNAFCQGKPGQRSIAASGGILLWPQSHFDWARPGIILYGVSPLEHKPWGPDFGFQPVMSLTSSLIAVRDHKAGEPVGYGGTWVSERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPNAQDNAGDPVVLWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYID
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  Provides the D-alanine required for cell wall biosynthesis.
What are the official names of this protein?
Alanine racemase, biosynthetic.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: HSP60_AJECA
Sequence: MQRALSSTSRASVLSSAPTRAPVSRFRSAGLSLQQQRFAHKELKFGVEGRAALLKGIDTLAKAVCTTLGPKGRNVLIESSYGSPKITKDGVTVAKAVTLQDKFENLGARLLQDVASKTNEVAGDGTTTATVLARAIFSETVKNVAAGCNPMDLRRGIQAAVEAVVEYLQANKRDITTTEEIAQVATISANGDTHVGKLISNAMEKVGKEGVITVKDGKTIEDELEVTEGMRFDRGYVSPYFITDTKAQKVEFEKPLIVLSEKKISAVQDIIPALEASTTLRRPLVIIAEDIEGEALAVCILNKLRGQLQVAAVKVPGFGDNRKSILGDIGILTNATVFTDELDMKLEKATADMLGSTGSITITKEDTIILNGDGSKDSIAQRCEQIRGVIADPTTSDYEKEKLQERLAKLSGGVAVIKVGGASEVEVGEKKDRVVDALNATRAAVEEGILPGGGTALLKAAANGLASVKPTSSDQLRRISSLVSAITRPARTIVENAGLEGSVIVGKLTDEHASDFNRGFDSAKGEYVDMIASGIVDPLKVVRTALVDASGVASLLGTTEVAIVEAPEEKGPAGPPGGMGGMGGMGGGMF
What is the function of this protein?
May participate in assembly and/or disassembly of proteins imported into the mitochondrion.  HSP60 are ATPases and have affinity for unfolded proteins.
What are the official names of this protein?
Heat shock protein 60, mitochondrial, Antigen HIS-62.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSRP_CITK8
Sequence: MDNVVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYQQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPGNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPTSLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPCLNSTNYSVEEIATKILDIMGLNRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: MLTF_AERS4
Sequence: MPIFSTRVLTYLRCIFRLFIGLMLLLTLVGCDFYTPSSQLEQIRQRGEIRVGTIYGSTSYYQRDDLAQGFDYELAKSYADWLGVKLTIVPVYSIAELVELLEKGKLDLAAAAIVVTPERRALFRFGPGFYQVSPKLVYRYGSPKPKDIGDLKGSIVVPAGSTGEDLLRELAKEYPGLKWSTNRDADVEELLKQVADGKIDYTVVQDTVLARTQRYYPELTEGLTLSKNQTVAWAMTKLPDDSLYASIIDFFGQRFMDGAIAKLDEKYFGHVQNFDFVDTRTFLQRAKSLLPKYQDLFKTHARMVDWRLLAAISYQESHWDPQARSYTGVRGMMMLTEPTAKAMGVKDRTHPAESIEGGARYLQHMMEKVPASVPTDEKVWFALTAYNIGYGHMMDARRLTKELGKNPDAWSDVKEVLPLLQQARWHRKVRYGYARGGEARNYVNNVRQYYQSLLWLDNEQQKAHRREELDEDDSSEPQSTERPTVIAEVVKQITLR
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: NU6C_POPAL
Sequence: MNLPGPIHDFLLVFLGLGLILGGLGVVLLTNPIFSAFSLGLVLVCISLFYILSNSHFVAAAQLLIYVGAINVLILFAVMFMNGSEYYKDFNLWTVGNGLTSLICTSLFVLLITIISNTTWYGIIWTTRANQIIEQDLVSNGQQIGIHLSTDFFLPFEFISIILLVALIGAIATARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GSTA2_RAT
Sequence: MSGKPVLHYFNARGRMECIRWLLAAAGVEFEEKLIQSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEFDASLLTSFPLLKAFKSRISSLPNVKKFLQPGSQRKPAMDAKQIEEARKVFKF
What is the function of this protein?
Catalyzes the conjugation of glutathione to a large variety of electrophilic compounds.
What are the official names of this protein?
Glutathione S-transferase alpha-2, GST 1b-1b, GST A2-2, Glutathione S-transferase Ya-2, GST Ya2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXA_CHLL3
Sequence: MNRGMKPINELISPDTKHYSFTEPFQTELGATLPSVEVAYRTWGTLNEARDNVILICHALTGSADADQWWGGLFGEGCGFDATRDFIICSNVLGSCYGTTGPLSPNPATGRHYGPDFPLITIRDMVHVERHLLRHLGIERVKLVVGASLGGMQVLEWGALYPEVALALMPMGISGRHSAWCIAQSEAQRQAIMADALWKDGWYEEDAPPARGLGAARMMAMCTYRSFRNFEEKFGRQRQEDGTFKAVSYMHHQGGRLVERFDANTYITLTRAMDMHDLGRGRSGYEEAVCAMTQPVEILSIDSDVLYPKSEQQELACLLPNSKILYLDEPYGHDAFLIDVERVSRMVRDFLQAISRKG
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_RHIME
Sequence: MVSLGGFARKLFGSANDRRVRGYKGRVDAINALEAEMKALSDEALAAKTAEFRRELADGKTLDDILVPAFAVVREAALRVLGLRPFDVQLIGGMILHERAIAEMKTGEGKTLVATLPVYLNALAGKGVHVVTVNDYLAQRDAGMMGRIYGFLGMTTGVIVHGLSDEQRRDAYACDVTYATNNELGFDYLRDNMKYERGQMVQRGHFFAIVDEVDSILVDEARTPLIISGPLDDRSDLYNTINEFIPLLSPEDYEIDEKQRSANFSEEGTEKLENMLREAGLLKGESLYDIENVAIVHHVNNALKAHKLFTRDKDYIVRNGEIVIIDEFTGRMMPGRRYSEGQHQALEAKEKVQIQPENQTLASITFQNYFRMYDKLAGMTGTAATEAEEFGNIYGLEVLEVPTNLPIKRIDEDDEVYRTVGEKFKAIIDEIKSAHERGQPMLVGTTSIEKSELLADMLKKSGFSKFQVLNARYHEQEAYIVAQAGVPGAVTIATNMAGRGTDIQLGGNPDMRIQQELADVEPGPEREAREKAIREEVQKLKEKALAAGGLYVLATERHESRRIDNQLRGRSGRQGDPGRSKFYLSLQDDLMRIFGSDRMDGMLQKLGLKEGEAIVHPWINKALERAQKKVEARNFDIRKNLLKYDDVLNDQRKVIFEQRIELMDAESVTDTVTDMRNEVIEEIVAKRIPERAYAEKWDAEGLKADVQQYFNLDLPIAEWVAEEGIAEDDIRERITAAVDKAAAERAERFGPEIMQYVERSVVLQTLDHLWREHIVNLDHLRSVIGFRGYAQRDPLQEYKSEAFELFQALLGNLRQAVTAQLMRVELVREAPEEPQPLPPMQAHHIDPLTGEDDFAQAGETLLAVAPANRDPADPSTWGKVARNEACPCGSGKKYKHCHGIYEA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PYRE_PYRHO
Sequence: MKMKDELINLIINEGCIKFGHFVLTSGKESNYYIDIKSLITNPKALRIIAKLIKEKAEELNLNYDKIAGPELGAVPIATALSLETNKPLLIVRKKKKEHGTGKVIEGNVQKGDKVLLVEDVTTTGGSVIRAAKILREHGADVVGIFVVVDREEGAKENIEKEGFKFYPLVLVSELFKAAGISKDQS
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RNH2_BACMK
Sequence: MQKMTIHEAECLLQEIMNEEDERFQMLVKDERKGVQKLILKWYKQKELAQKEREKFLEMSKYENELREKGLTYIAGIDEVGRGPLAGPVVTAAVVLPEDFYIPGLNDSKKLSEAKRERFYDEIKDHAIAIGVGIISPQVIDEINIYQATKQAMLDAVANLSCTPEYLLIDAMKLPTSIPQTSIIKGDAKSVSISAASIIAKVTRDRMMKELGGKYPAYGFEQHMGYGTKQHLEAIEVHGVLEEHRKSFAPIKDMIQK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP125_RHOJR
Sequence: MGSFPCPQKIEQVLLSGQGLNELSFASRPACASMLVERVPHHGVVYGLGQETAVAQPNLPEGFDFTDPDVYAERIPYQEFAELRKTAPIWWNPQPPEIGGFHDDGYWVVSKLEDVKEVSRRSDVFSTHENTAIVRFADDIPRENIEMQRFILINKDAPEHTKLRKLVSRGFTPRAINSLREELTERAEKIVKEAAESGAGDFVTQVACELPLQAIAELLGVPQEDRLKVFDWSNQMTGYDDPELDIDPQAASMEILGYAYQMADERKKCPADDIVTTLIEADIDGNELSPEEFGFFVILLAVAGNETTRNAITHGMMAFLDHPDQWELYKKERPKTTADEIVRWATPVNSFQRTALEDTELGGVQIKKGQRVVMLYGSANFDEDAFENPEKFDIMRENNPHVGFGGTGAHFCLGANLARLEIDLIFNAIADHLPDISKLGDPRRLRSGWLNGIKEFQVDYKTASGGCPVRH
What is the function of this protein?
Involved in the utilization of cholesterol as the sole carbon and energy source by degrading the side chain.  Primarily catalyzes the sequential oxidation of the terminal methyl of cholest-4-en-3-one into (25S)-26-hydroxycholest-4-en-3-one (alcohol), (25S)-26-oxocholest-4-en-3-one (aldehyde), to finally yield the carboxylic acid (25S)-3-oxocholest-4-en-26-oate.  Also able to sequentially oxidize cholesterol itself, not only cholest-4-en-3-one.
What are the official names of this protein?
Steroid C26-monooxygenase, Cholest-4-en-3-one 26-monooxygenase, Cholest-4-en-3-one C26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming], Cholesterol C26-monooxygenase, Cholesterol C26-monooxygenase [(25S)-3beta-hydroxycholest-5-en-26-oate forming], Cytochrome P450 125, Steroid C27-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RECX_SHIF8
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.