PharMolix/UniProtQA huggingface dataset:
Protein: ABHD5_PIG
Sequence: MAAEEEEMDSTDACERSGWLTGWLPTWCPTSTSHLKEAEEKILKCVPCIYKKGPVRISNGNKIWTLKLSHNISNKIPLVLLHGFGGGLGLWALNFGDLCTNRPVYAFDLLGFGRSSRPRFDTDAEEVENQFVESIEEWRCALGLDKVILLGHNLGGFLAAAYSLKYPSRVSHLILVEPWGFPERPDLADQERPIPVWIRALGAALTPFNPLAGLRIAGPFGLSLVQRLRPDFKRKYSSMFEDDTVTEYIYHCNVQTPSGETAFKNMTIPYGWAKRPMLHRIGKMNPDIPVSVIYGARSCIDGNSGTSIQSLRPHSYVKTIAILGAGHYVYADQPEDFNLKVKEICDTVD
What is the function of this protein?
Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfert of an acyl group on a lysophosphatidic acid.  Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1-stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor.  Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors (By similarity).  Functions in phosphatidic acid biosynthesis (By similarity).  May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2 (By similarity).  Involved in keratinocyte differentiation (By similarity).  Regulates lipid droplet fusion (By similarity).
What are the official names of this protein?
1-acylglycerol-3-phosphate O-acyltransferase ABHD5, Abhydrolase domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Lipid droplet. Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity).
Protein: NAGB_GEOSW
Sequence: MKLIEAANYEEMSQKAADIIIAQVKEKPDSVLGLATGSTMLGTYKQLVEDHRQNGTSYRNVRTVNLDEYIGLSPDHPNSYRYYMNQHLFSHIDIPLSQTYIPNGASDDVEAECRRYEQLIESLGGIDLQLLGIGRNGHIGFNEPGTSFSAPTHVVELAPSTRQANARFFPSFNDVPRQAITMGIATIMKSRHILLLASGTAKAPIMAKLFEETVTTDVPASVLHTHPNVTVIADQDALSLVPDEKRKVYAK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: LDH_HALH5
Sequence: MAITKGNKIVLVGTGAVGSSYAYALMNQGISDELILVDLNEEKAKGDVLDLNHSIVYAPSPMEIKFGSYEDCKDAALVVICAGAAQKPGETRLDLVHKNVGIFESIVGNIMKSGFNGIFLVATNPVDILAYATWKFSGLPKERVIGSGTVLDTARFRYLLGEEMNAAPTSVHGYIIGEHGDSQLPVWSSATIAGTPIAPRLTDEKKQEIAENVRDAAYKIIEAKGATYYGIATGLARITRAILKNENVVLPVGTLLEGENGHDDVYIGVPAIINREGVRQVVELSLNDEEKEKFARSVETLKDIQAAIWS
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
Protein: ADH_DROYA
Sequence: MAFTLTNKNVVFVAGLGGIGLDTSKELVKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDVTVPIAETTKLLKTIFAQLKTIDVLINGAGILDDHQIERTIAVNYTGLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAHPTQPSLACAQNFVKAIELNQNGAIWKLDLGTLEAIQWSKHWDSGI
What are the official names of this protein?
Alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SBNO_CAEEL
Sequence: MDDILSAALAESGLDFLCQQSSPTPSTSGSIHDDAGQSFSNNTHTPSVSQFFDETSNDSHSSSAYYTPMATPFVSTEDGGVPTSFFGMDEEDGGCTIMTTAGTSGSNNIDGIEDAGGGMYYPHVKVIPRKHTAPTVNQSEPSTPTVTIVPKKEDPLFETNTADSPTPSGDTSTTASYEGNDGLEDQETTSDRQNPMFVQTARSTDGRLDTPSTSATVSPHITSSLTQRSHTSSPASSASEGTVVPPRKKGLPITTGSIVKRTVQTKDGLQTQYLKAFVNENGEKIYKLLSPVAASAVARGTLPPGMGRGGSTIGRGGTMVNKNGERLMVVKNHVGPNGQMLVKRMVSPAGTRIVANGGQGRGQPIYRAVDGSNGPTHLLRRTTTTGQPTRGAPVGMAARHAVRGGTVYGGGNGYRVNLVGRGTGGSTMVHHQPLNRISSQRSVAPVGRVLNRGALRNGAQQPLHVSTSSPAFHYMEEQPSPTTNGMVIQAKTPGAGVIQARHMQSQQSFPSGGPARVLMNRSSTNAGLSRMVGGGYDQQLPTAPNGRLMIPSTAVRVPGSGMASPRLQTTPQPLTKSQKAKDEMKMAYQVGREEALQQRRNDLEDDEENLGYAETYSEYTPAKLRSGMAHPDSVVESASLSSVSPPDVKYQISIPEYLIDMGHISALQLEAVIYACQMHERRMPSGERYGYLIGDGAGVGKGRTVACIIFENYLQGRKRAIWLSVSSDLKFDAERDLRDCGAPNIPVYALNKMKYAKISGKENGSIKKGVMFATYTSLIGECRGAKSRKYRSRISQLIQWFGQDYDGVIILDECHRAKNLVPTAGAKPTKTGRMVLELQKALPNARVVYASATGATEPRNMAYMTRLGLWGERQAFPEFHDFISAVERRGVGAMEIVAMDMKQRGLYLARQLSFRGVSFAVQEVQLSSEFVKMYDAAVKLWMEARRQFQTVIETMDEEERSTCKTVWGQFWACHQRFFKYLCIAAKVDTCVQLSREAIKAKKCVVIGLQSTGESATLETLEEMGGELNEFVSTAKTVLYGLIDKHFPTDASFSMGDRDIFKDFDDFERPAKRRKTRETLSFLGDVGFDTWTGVTTGMGGRVGDGVTKNITRGLSGIGRSSMSSSTGNTNNEDANSTTSESSDGSDDEVENDMISENGGESGDLESAREEAEGARTLEDGEQDEWVKALLAEAESSSDDSDEEVVKDEDEDEEAESKSGETHEQEEEFNPFMCDFTNDDPWAHNQQIVEDTPQKDRKAKKRKRDEEEAERLREKVRKREERREKKRRRAIRRAEREKQRRNEELQARGSATDFITSSRICGNGSGEQDDINPMLIKTELLAAVERLAPSLPANTLDQLIDEMGGPEYVAEMTGRRGHMVTSETGDVMYQRRNANAEVSLELINMEEKEKFMRGEKLIAIISEAASSGISLQSDRRAINKRRRVHITLELPWSADKAIQQFGRTHRSNQVSGPEYVFLISELAGEKRFASIVAKRLESLGALTHGDRRATETRDLSQFNMDNKYGRVALDTLLKTVIGQAGTPLIDPPKDYKAGEFFEDMRLYMEGVGLLAKNKTGQYTIEKEAATIPKFLNRILGLPVHAQNSLFHYFSEIVAELIAQSKHDGTYDTGIMDLGTGDDQVRKLETRVFTGRVDNGSFRVEIHKIGVERGVSWEEAMELHKEHSNDDDGFYICHPGGANTANTKKVAALVYGIGKIRMDNGARLYAITRPSTGRSPKLMTMADLSKRFHKVSIDEAKEVWKQQYDSAANMCQHNYVYGKCRTESNGTYCEVGRRTRTYFVLSGSVLSVWPIVEEVLAGSDRKSSRMQVIRVRTEQDQKIVGLLVLPTHVRHLVQQLETHCGRSYVKTEP
What is the function of this protein?
Transcriptional activator that functions upstream of the let-60/Ras and let-23/EGFR signaling pathways to positively regulate lin-3 expression and thereby promote vulval induction (PubMed:20230814).  Plays a role in excretory duct development (PubMed:20230814).  Plays a role in male tail development (PubMed:20230814).
What are the official names of this protein?
Protein strawberry notch homolog, Lethal protein 765, Notch signaling pathway homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SBNO family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDRP2_LISIN
Sequence: MENPVIIYVISDAIGETAQHIIRAVTAQFSLNKPADIRRHAFIRDENALLETLEEAKAADGIVVQTLVQSKLADYASNFCVKNHLQNVDLLHTLTAAVEAKTGLKSKQDPGNMRRLDSNYFDRIAAIEFAVKYDDCKDPRGLLDADIVLVGVSRTSKTPLSSYLANQNWKVANVPLVPEIPIPDELFQIPAERIIGLTTTPEKLAQIRKVRLKSIGLDEASSYSSEKRILEELEYGYATFKKLGCQVIHVEDKAIEETAALITEIITSYH
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 2, PPDK regulatory protein 2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RS6_BACC7
Sequence: MRKYEIMYIIRPGVEEEAQKALVERFAGVLTNNGAEIINTKEWGKRRLAYEINDLREGFYMILNVNANAEAINEFDRLAKINEDILRHIVVKEEEK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RL2_HELPG
Sequence: MAIKTYKPYTPSRRFMSVLDSKDITAKSSVKGLLTKLKATAGRNNNGRITSRHKERGAKKLYRIIDFKRNKYNIEGKVAAIEYDPYRNARIALVVYPDGDKRYILQPSGLKVGDSVIAAEGGLDIKVGFAMKLKNIPIGTVVHNIEMHPGAGGQLARSAGMSAQIMGRENKYTILRMPSSEMRYILSECMASVGVVGNEDFINVSIGKAGRNRHRGIRPQTRGSAMNPVDHPHGGGEGKTGTSGHPVSPWGTPAKGYKTRKKKASDKLIISRKKHK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CATJ_RAT
Sequence: MTPAVFLVILCFGVASGAPARDPNLDAEWQDWKTKYAKSYSPVEEELKRAVWEENLKMIQLHNKENGLGKNGFTMEMNAFADTTGEEFRKSLSDILIPAAVTNPSAQKQVSIGLPNFKDWRKEGYVTPVRNQGKCGSCWAFAAVGAIEGQMFSKTGNLTPLSVQNLLDCSKSEGNNGCRWGTAHQAFNYVLKNKGLEAEATYPYEGKDGPCRYHSENASANITGFVNLPPNELYLWVAVASIGPVSAAIDASHDSFRFYSGGVYHEPNCSSYVVNHAVLVVGYGFEGNETDGNNYWLIKNSWGEEWGINGFMKIAKDRNNHCGIASQASFPDIF
What are the official names of this protein?
Cathepsin J, Cathepsin L-related protein, Cathepsin P, Catlrp-p.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RXLRA_PHYIT
Sequence: MRCYYVLIAIAAVLSGIATAAADSRHNKLAAVDSDKTTDRVELFLRRNDELDAENTDERIVAGAIPLNARIIKRLVKLEKKMVDPKLADDLLEGTTLKTELDAALPYAGRTQVFERWHAQGLDPSSITKAVNIHPAIEKKYRIVYMMYELFVKSADKKRLAKLKRKRTND
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves, which suggests that PITG_22798 contributes to P. infestans infection (PubMed:28216607).  Triggers cell death in Nicotiana benthamiana.  PITG_22798-triggered cell death is dependent on SGT1-mediated signaling but not HSP90, and is suppressed by the P. infestans avirulence effector 3b (AVR3b) (PubMed:28216607).
What are the official names of this protein?
RxLR effector protein PITG_22798.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Lovalization to host nucleus is require to induce cell death.
Protein: SSTT_ACTP2
Sequence: MSNPSLSSKLLGGNLVLRIAIGLVLGACLALVNPDWAKNVGVLGQFFVKSLRAIAPILVFVLVLSAIANKEVGSDSKLKPILVMYVLGTFVAALTAVVLSFMFPTTLELVSNPDNLNPPQGIGEIIKTVVFNLVDNPLQALANANFIGILAWAIGLGIALRHAAPSTKTFLNDFAEAVSFVVKVVIAFAPIGVFGLVAETIATNGADAFVGYARLLGVLLGAMVIVAFVLNPLIVFWKIRRNPYPLTLTCLRESGVTAFFTRSSAANIPVNMNLAKRLGVRDEIASVAIPLGATINMAGAAITVTVLTLAAAYTQGIQPDFATALLLSIVASVCACGASGVAGGSLLLIPLACSLFNIPNDIAAQVIGVGFIIGVIQDSAETALNSSTDVLFTAAVSQAEDQKA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OPSB_ARTBC
Sequence: MRGDSFIWSLATAIPLLSTAVESLQVVKRDNPSVLGFDIERFQVAKPIHRDIIAKRASTKTISQDLDNQKNLYFCNLTLGTPPQTIRAHIDTGSSDLWVNTAESRFCSSRRAPCSQGGTYDSSSSSTYQLVNNDFNISYVDGSGATGDYVTDVINVGGIKLKDFQFAIGHTSSSPLGVLGIGYEAGEAQVTRSGDQSYPNLPAALVKAGHIRSNAYSLWLNDLSASRGQILFGGIDTGKFQGKLQTVPVLHTSRGDYTSLVVALTGVGIRTGSDGSIDTFPSQPVAVAMDSGSSLSYLPDALAAKVYNSVDAVFDPANNLAFVPCSMANDKRKLVFTFSSPQIAVGMDELVIDLGPDANGNEATFRDGSKACVFGIAPAGSSISILGDTVLRSAYLVYDLDNNEISIAPTRFNSTETNILEIGTGENSVPDATGVPNAVTSAQVTQATGLPGVETGVPGSRPPSSKAAGQAKRPDFVLGVAAVGLAGAGMLFAAM
What is the function of this protein?
Probable GPI-anchored aspartic-type endopeptidase which contributes to virulence.
What are the official names of this protein?
Probable aspartic-type endopeptidase OPSB.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: RL25_PHOPR
Sequence: MKFNAVVRTDLGKGASRRLRLTEKFPAIIYGGEAAPVAIELLHSDVINQMDKPEFYEGIILVIDGQEVAVKPQDIQRHVFKPKVEHMDFKRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: Y528_METMP
Sequence: MLKKLYSKKGQVSMEMGILVASAVAVAAIASYFYAVNVKYSDTHAGETAKNTSNALINVTENVCGNISEITIP
What are the official names of this protein?
UPF0333 protein MMP0528.
What is the protein family that this protein belongs to?
Belongs to the UPF0333 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DCUP_SALTO
Sequence: MARWATMSTETTGTGARDEGPRPGDPADSPFVRACRRKPGPHTPVWFMRQAGRSLPEYRKIRASVAMLESCRRPELITEITLQPVRRHGVDAAILFSDIVVPVAAAGVALDIVPGTGPVVNDPVTTAADVDRIRPISREDVPYVDEAVRMLVGELGATPLIGFAGAPFTLASYLIEGGPSRNHTKTKALMYGDPDLWHALASRLAEVTLAFLKVQIDAGVSAVQLFDSWAGALSEADYRRYVQPHSQAVLAGLADAGVPRIHFGVGTGELLAAMGEAGADVVGVDWRTPLDVATRRVGSERAVQGNLDPCLLFAPWPVIEAEVRRVLAQGRAAPGHIFNLGHGVLPETDPDVLTRVVALIHELTARPNARS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRCH4_MOUSE
Sequence: MAAAVAGPLAAGGEEAAASVSLPGSPGLPGSRSAERALEEAVATGTLNLSNRRLKHFPRGAARSYDLSDITQADLSRNRFPEVPEAACQLVSLEGLSLYHNCLKCLNPALGNLTALTYLNLSRNQLSSLPPYICQLPLRVLIISNNKLGALPPDISTLGSLRQLDVSSNELQSLPVELCSLRSLRDLNVRRNQLSTLPDELGDLPLVRLDFSCNRISRIPVSFCRLRHLQVVLLDSNPLQSPPAQICLKGKLHIFKYLTMEAGRRGAALGDLVPSRPPSFSPCPAEDLFPGRRYDGGLDSGFHSVDSGSKRWSGNESTDDFSELSFRISELARDPRGPRQPREDGAGDGDLEQIDFIDSHVPGEDEDRSAAEEQLPSELSLVAGDVEKPSSSRREEPAGEERRRPDTLQLWQERERKQQQQSGGWGSPRKDSVLKRGIRAAGAGASAPSTQATCNGPPKSSTTQLGVSGGQGAPTPPPTSQDPLPVSGPVTAPVPRPLGSIQRPNSFLFRSSSQSGSSPSSPESVLRPRPFPQEKELISQLRQVLESRLQQPLPEDLAEALANGVLLCQLANQLRPRSVPFIHVPSPAVPKLSALKSRKNVESFLEACRKMGVPEADLCSPSDLLRGTAQGLQTVLEAVILVGGKAPLPVQPSSGLGGFLLFYVVFMLLLYVVYTRLLGS
What are the official names of this protein?
Leucine-rich repeat and calponin homology domain-containing protein 4.
Protein: YHE5_SCHPO
Sequence: MECPIIALSVGFSNNSQPYVEAIIKAGGCPIVIYPGLQRNSIPPNIDGIILAGGESVHPNRYGEDFDPNAPKSVDVIRDSTEWGMIDFALKKKIPILGICRGCQVLNVYFGGSLYQNVSSCGFRDIHRPSKPRHYLAHKVMAKPGKLKNILGSNVIDVNSIHDQGIKTLGMGLQSTVISDDGLCEGIESKDGLIIGVQWHPEAIIDKQPHSLKLFQYFINRSKWHMKQSNIFSNVPHESSFYRNSIISIPIAP
What are the official names of this protein?
Putative glutamine amidotransferase PB2B2.05.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: A1AT3_MOUSE
Sequence: MTPSISWGLLLLAGLCCLVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIVEAVKKLDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDESTTVKVPMMTLSGMLDVHHCSTLSSWVLLMDYAGNATAVFLLPDDGKMQHLEQTLSKELISKFLLNRRRRLAQIHFPRLSISGEYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSQAVHKAVLTIDETGTEAAAVTVLLAVPYSMPPILRFDHPFLFIIFEEHTQSPLFVGKVVDPTH
What is the function of this protein?
Inhibitor of serine proteases.  Can inhibit trypsin and chymotrypsin; relatively ineffective against elastase.
What are the official names of this protein?
Alpha-1-antitrypsin 1-3, Alpha-1 protease inhibitor 3, Alpha-1 protease inhibitor 6, Alpha-1-antitrypsin 1-6, Serine protease inhibitor 1-3, Serine protease inhibitor 1-6, Serine protease inhibitor A1c, Serpin A1c.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCD1_YEAST
Sequence: MILSQRRMLSSKQLIENLIRYKFHKTPYTRSSIWPFKRNSAVIILLFIGMKGELRVLLTKRSRTLRSFSGDVSFPGGKADYFQETFESVARREAEEEIGLPHDPEVLHKEFGMKLDNLVMDMPCYLSRTFLSVKPMVCFLYKDKLEKHEDKYKVPLDIRKFFGKLNPGETSSLFSVPLNDLVIHLLPEADEDVKSYQAEYFERKEYKLNWGGIKWLIMHYHFHVANNNEMPWLQTIEDLSSSDEDGVDGGIFRFRDLWGLTCKILFDVSCIANGLMDEKLKGELGHEDLIVGLHDYGNQMQPNGRSEWEIGMINGDRNLKYSDVIPEYYMKHLLECRSLW
What is the function of this protein?
Coenzyme A diphosphatase which mediates the cleavage of CoA into 3',5'-ADP and 4'-phosphopantetheine.  Has a strong preference for oxidized CoA disulfide (CoASSCoA) as substrate.  May be required to remove potentially toxic oxidized CoA disulfide to maintain the capacity for beta-oxidation of fatty acids.  Can degrade 8-oxo-dGTP in vitro; however, such activity may not be relevant in vivo.
What are the official names of this protein?
Peroxisomal coenzyme A diphosphatase 1, peroxisomal.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: LEUD_ANADF
Sequence: MEPIRTIESRTVVIPRENIDTDQIIPGRFLKVTDKKGLGKALFSDWRYDAGGGPRADFVLNGPAAEGCTVLVAGDNFGCGSSREHAPWALVDYGIRAVVSTRVADIFRNNALKNGLLPIVLDPASHAKLLAAPGASVRIDLASQTISLPDGSTASFPLDGFAKYCLMNGVDELGFLLSQEESIAAFETRSKV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: LHTL8_ARATH
Sequence: MDERPETELISIPATPRVSTPEILTPSGQRSPRPATKPSSATWTPTSFISPRFLSPIGTPMKRVLVNMKGYLEEVGHLTKLNPQDAWLPITESRNGNAHYAAFHNLNAGVGFQALVLPVAFAFLGWSWGILSLTIAYCWQLYTLWILVQLHEAVPGKRYNRYVELAQAAFGERLGVWLALFPTVYLSAGTATALILIGGETMKLFFQIVCGPLCTSNPLTTVEWYLVFTSLCIVLSQLPNLNSIAGLSLIGAVTAITYSTMVWVLSVSQPRPATISYEPLSMPSTSGSLFAVLNALGIIAFAFRGHNLVLEIQSTMPSTFKHPAHVPMWRGAKISYFLIALCIFPISIGGFWAYGNLMPSGGMLAALYAFHIHDIPRGLLATAFLLVVFSCLSSFQIYSMPAFDSFEAGYTSRTNKPCSIWVRSGFRVFFGFVSFFIGVALPFLSSLAGLLGGLTLPVTFAYPCFMWVLIKKPAKYSFNWYFHWGLGWLGVAFSLAFSIGGIWSMVTNGLKLKFFKPPN
What is the function of this protein?
Amino acid transporter.
What are the official names of this protein?
Lysine histidine transporter-like 8, Amino acid transporter-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DTD_STRSY
Sequence: MKIVLQRVSQASVTIEGSIHGQIEQGLLLLVGVGPDDSQEDLDYAVRKIVNMRIFSDEAGKMNKSVQDVAGKILSISQFTLFADTKKGNRPAFTGAAAPALASQLYDAFNQALSAFVPVEVGVFGADMAVSLVNDGPVTIVLDTKNK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_NEIMA
Sequence: MKDCFPQGLNGKKTAVALSGGLDSVVLLHLLVRAGKKGGFIPDALHIHHGLSPRADDWADFCQNYCDMLGVGLETVKVCVEKNGLGIEAAARQKRYAAFAEKGFDVLALAHHRDDQIETFMLAVARGGGLRALAAMPAVRPFGEKGIIWRPLLPFSRQDIWDYAQKHGLPNIEDESNTDTAYLRNRFRHRILPELSAQIPHFGRHVLNNVRALQEDLALLDEVVVQDCRWVCGAGYFDTARWLTFSPRRKTHILRHFLKENGIPVPNQNALADIARVLTEAKTGRWNLQGFELHHYAGRLFVFRLEKTDKLRFLKDRQISGNLREILTGQGFVLKRHPFGLPEHLLEQDGILRTVAASDTLAMGGIHKDVKKILQGKRVLPVLRPIWPLVADSGNRPLALANCCADFQYSVSDGILPVHPDFPILF
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_SALRD
Sequence: MTGHLPRLLSPFSPDRLPVMDAPVIEAQPRETGSKAAREIRNNDRVPCVLYGRTVESTPLQIPIAALNKLIYRRSAPVAEVEMNGDTWNCILKDYDLHPLTDRPLHADFQALEEGDEVTLTVPLNYTGIPVGQQNGGDTQQIARELTISVLPENIPAQIEVDIGELVIGDSLHVYDLETDYEIKTSRDQTLVTVVAPQIETAPTTEAEEEEEELTEEEIAEEGEAVDTEEGEPAEGEEAAGEGGADEEYQ
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: UHMK1_MOUSE
Sequence: MAGSGCAWGAEPPRFLEAFGRLWQVQSRLGSGSSASVYRVRCCGTPGSPPGALKQFLPPGTTGAAASAAEYGFRKERAALEQLQGHRNIVTLYGVFTIHFSPNVPSRCLLLELLDVSVSELLLYSSHQGCSMWMIQHCARDVLEALAFLHHEGYVHADLKPRNILWSAENECFKLIDFGLSFKEGNQDVKYIQTDGYRAPEAELQNCLAQAGLQSDTECTSAVDLWSLGIILLEMFSGMKLKHTVRSQEWKANSSAIIDHIFASKAVVNAAIPAYHLRDLIKSMLHDDPGRRIPAEMALCSPFFSIPFAPHIEDLVMLPTPVLRLLNVLDDDYLENEDEYEDVVEDVKEECQKYGPVVSLLVPKENPGRGQVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYKRGYLYQTLL
What is the function of this protein?
Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase.  May be involved in trafficking and/or processing of RNA (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase Kist, Kinase interacting with stathmin, PAM COOH-terminal interactor protein 2, P-CIP2, U2AF homology motif kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Note=Mostly nuclear.
Protein: CNBL4_ARATH
Sequence: MGCSVSKKKKKNAMRPPGYEDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQLALFRNRNRRNLFADRIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELKEMVVALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSLNPSLIKNMTLPYLKDINRTFPSFVSSCEEEEMELQNVSS
What is the function of this protein?
Acts as a calcium sensor involved in the regulatory pathway for the control of intracellular Na(+) and K(+) homeostasis and salt tolerance.  Binding of a CBL protein to the regulatory NAF domain of a CIPK serine-threonine protein kinase lead to the activation of the kinase in a calcium-dependent manner.  Operates in synergy with CIPK24/SOS2 to activate the plasma membrane Na(+)/H(+) antiporter SOS1.  Involved in salt stress responses by mediating calcium-dependent microfilament reorganization.  The CBL4/CIPK6 complex mediates translocation of AKT2 from the endoplasmic reticulum to the plasma membrane.  Both myristoylation and S-acylation are required for AKT2 activation.
What are the official names of this protein?
Calcineurin B-like protein 4, Protein SALT OVERLY SENSITIVE 3.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cytoplasm. Nucleus. Note=The cell membrane localization is S-acylation dependent.
Protein: VAPB1_MYCTU
Sequence: MATIQVRDLPEDVAETYRRRATAAGQSLQTYMRTKLIEGVRGRDKAEAIEILEQALASTASPGISRETIEASRRELRGG
What is the function of this protein?
Antitoxin component of a possible type II toxin-antitoxin (TA) system.  The cognate toxin is VapC1.
What are the official names of this protein?
Putative antitoxin VapB1.