PharMolix/UniProtQA huggingface dataset:
Protein: QUEA_CROS8
Sequence: MRLTDFSFELPESLIAHYPQAQRSACRLLSLDGPTGDLTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDHRVLAHIRASKAPKPGAELLLGDDESVNATMTARHDALFEVQFNDARPVLDILNSIGHMPLPPYIERPDEEADRELYQTVYSQKPGAVAAPTAGLHFDEPLLERLRAKGIEMAFVTLHVGAGTFQPVRVESIEDHVMHSEYAEVPQEVVDAVLAAKARGNKVVAVGTTSVRSLESAAQAAQDALIAPFFGDTQIFIYPGYQYKVIDALVTNFHLPESTLIMLVSAFAGYKHTMNAYREAVKAEYRFFSYGDAMYITYNPQAINERPGE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTA_PSARE
Sequence: EDCLGWFSRCSPKNDKCCPNYKCSSKDLWCKYKIW
What is the function of this protein?
Gating-modifier toxin that both inhibits the peak current of human Nav1. 1/SCN1A, rat Nav1. 2/SCN2A, human Nav1. 6/SCN8A, and human Nav1. 7/SCN9A and concurrently inhibits fast inactivation of human Nav1. 1 and rat Nav1. 3/SCN3A.  The relative rank order potency for Nav modulation is Nav1. 3 (inactivation EC(50)=45 nM) > Nav1. 7 > Nav1. 2 > Nav1. 1 (inactivation) > Nav1. 1 > Nav1. 6 > Nav1. 3 (IC(50)=8 uM).  The DII and DIV S3-S4 loops of Nav channel voltage sensors are important for the interaction of this toxin with Nav channels but cannot account for its unique subtype selectivity.  It is the variability of the S1-S2 loops between NaV channels which contributes substantially to the selectivity profile observed for this toxin, particularly with regards to fast inactivation.  This toxin may bind the channel in the resting state (Probable).
What are the official names of this protein?
Beta/delta-theraphotoxin-Pre1a, Beta/delta-TRTX-Pre1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_BORAP
Sequence: MSKKGKKYIEAFSKVDKSKFYSIEDAISLLKEIKFVKFDETIDISVNLNLKKNHTVRDTIVLPNQFMKPKRILVFAKGDRADEARAFGATYVGDDDLINKIKSGWDEFDIVVATPDMMKDVGRLGPILGKRGLMPNPKTQTVTNNLKDAINSLKKGRTEFRANKNGVISFSFGKSSMDNEKIKENYEEFIKEVVKKRPSDLKGTFIDSIYISSTMGPSIRVEFVWR
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: BIOD_ALIF1
Sequence: MIDAFFIAGTDTDVGKTVASKAILDALNMKGLRTAAYKPVAAGSEDKGEGVQNSDAIHLRAVANVELRYEEVNPYALLMPASPHIAAEAENVVIDYSVLSEGLASLKEKSDVVLVEGAGGWRVPVSKDDCLSTWVQQEKLPVVLVVGIKLGCLSHAMLTAEAIQHDGLEIIGWVANRVNPGTENYAEIIKMLEDKMPAPKLGEIPYMPSVKRKNMGKYIHLEALDN
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PO210_MOUSE
Sequence: MARASLVQPALWALLLLQVVGPAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWSSTRPEVASIEPLGSSEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHGIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFDWTIVKDTEANGFSDSHNALRILTFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLILENILLNPAYDVYLLVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPDPQGDPARPVAILTQDTSRVTAMQMGQSNLVLGHRSIRMQGASRLPNSTIYVVEAGYLGFTVYPGDRWVLETGHLYAITIEVFDRSSNKVYPSDNIRIEAVLPAEFFEVLSSSQNGSYHHIRAIQSGQTAISATLTSVVDQDGGVHVLQVPVWNQQEVDIHIPITLYPSILTFPWQPKTGAYQYTIKAHGGSGNFSWSSSSSMVATVTVKGVMTTSGDTGLSVIRAHDVQNPLHFGEMKVYVIEPSSMEFAPCQVEARVGHTLELPLTISGFMPGGGSEVVTLSDCSHFDLVVEVENQGVFQPLPGRLPPGPEHCSGVKVKADAQGSTTLLVSYTHGHVHLDAKITLAAYLPLKAVDPSSVAVVTLGSSKEMLFEGGPRPWVLEPSKFFRNVTSEDTGSISLSLLGPPASRNYQQHRVLMTCQALGEQVIALSVGNRPSLSNPFPAVEPTVVKSICAPPSRLTLMPVYALPQLDLSCPLLQQNKQVVPVSSHRNPLLDLGAYDQQGRRFDNFSSLSIQWESSRPLLASIELDQPMQLVSQDDGNGQKKLHGLQTVSVHEASGTTAISATATGYQQSHLSEARVKQPHDPLVPVSASIELILVEDVRVSPEEMTIYNHPGVQVELYITEGSGYFFLNTSTQDIIKVAYQDTRGVALVHPLLPGSSTVMVHDLCLAFPAPAKAIIHVSDIQELYVRVVDKVEIGKAVKAYVRVLDFYKKPFLAKYFTFMDLKLQAASQIITLVTLDEALDNYTATFLVHGVAIGQTSLSASVTDKSGQRVSSTPQQIEVFPPFRLIPRKVTLIIGAMMQITSEGGPQPQSNILFSINNESVAAVSSSGLVRGLMVGNGSVLGVVQAVDAETGKVIIVSQDLVEVEVLQLQAVRIRAPITRMRTGTQMPVFVTGITSNQSPFSFGNAVPGLTFHWSVTKRDVLDLRGRHHEVSIRLPPQYNFAMNVYGRVKGRTGLRVVVKALDPTAGQLHGLGKELSDEIQIQVFEKLRLLNPEIEAEQILMSPNSFIKLQTNRDGAAILSYRVLDGPEKAPIVHTDEKGFLVSGSGIGVSTLEVIAQEPFGTNQTILVAVKVSPVSYLRISMSPVLHTQHKEALTALPLGMTVTFIVHFHDSSGDIFHAHNSVLNFATNRDDFVQIGKGATNNTCIIRTVSVGLTLLHVWDVEHLGLSDFVPLPVLQAITPELSGAVVVGDILCLASVLTSLGGVSGTWSSSASHVLYVDPKTGVAIARDAGSVTVYYEIAGQLKTFKEIVVGTPQKIVARRLHSAQTSIQEATASKVTVSVGDRSSNLLGECSPAQREAIEALHPESLISCQLQFKQDVFDFPACDVFTVEPGFDAALGQYLCSVTMRRLTDKQLKHLNMKKTSLAVTASIPSSYTSVEKVGAEVPFSPGLYANQAEILLSNHYTSSEVKVFGAVESLENLEVKSGSPAVLAFVKEKSFGLPSFITYTVGVLDPTAGSQGPLSTALTFSSPATNQAITIPVTVAFVLDRRGPGPYGASLLSHFLDSYQVMFFTFFALLAGTAVTIIAYHTVCAPRELASPLALTPRASPQHSPHYLASSPAAFNTLPSGRKASPPSGLWSPAYASH
What is the function of this protein?
Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.
What are the official names of this protein?
Nuclear pore membrane glycoprotein 210, Nuclear pore protein gp210, Nuclear envelope pore membrane protein POM 210, POM210, Nucleoporin Nup210, Pore membrane protein of 210 kDa.
What is the protein family that this protein belongs to?
Belongs to the NUP210 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single- pass type I membrane protein.
Protein: DNAJ_SALNS
Sequence: MAKRDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDAQKRAAYDQYGHAAFEQGGMGGGFGGGFNGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMDLTLEEAVRGVTKEIRIPTLEECDVCHGSGAKAGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCHKCHGHGRVEKSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVMLKVPSETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLSEKQKQLLKDLQESFGGPTGEKNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXZ05_LYCSI
Sequence: MMKVLVVVALLVTLISYSSSEGIDDLETDELLSLMANEQTRAKACTPRYYDCSHDRHSCCRSSMFKDVCTCFYPEGGDNKEVCTCQQPKHLKYMEKATDKIKNLFG
What are the official names of this protein?
Toxin-like structure LSTX-D5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 02 (D7) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y175_HELPY
Sequence: MKKNILNLALVGALSTSFLMAKPAHNANNATHNTKKTTDSSAGVLATVDGRPITKSDFDMIKQRNPNFDFDKLKEKEKEALIDQAIRTALVENEAKTEKLDSTPEFKAMMEAVKKQALVEFWAKKQAEEVKKVQIPEKEMQDFYNANKDQLFVKQEAHARHILVKTEDEAKRIISEIDKQPKAKKEAKFIELANRDTIDPNSKNAQNGGDLGKFQKNQMAPDFSKAAFALTPGDYTKTPVKTEFGYHIIYLISKDSPVTYTYEQAKPTIKGMLQEKLFQERMNQRIEELRKHAKIVINK
What are the official names of this protein?
Putative peptidyl-prolyl cis-trans isomerase HP_0175, PPIase HP_0175, Rotamase HP_0175.
Protein: Y443_STAAW
Sequence: MDSHFVYIVKCSDGSLYTGYAKDVNARVEKHNRGQGAKYTKVRRPVHLVYQEMYETKSEALKREYEIKTYTRQKKLRLIKER
What are the official names of this protein?
UPF0213 protein MW0443.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: ATPB_ASPND
Sequence: IGKAHGGVSVSGGVGERTREGNXLYMEMKESKVINEQNISESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTSAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPWIVGEEHYDTAQGVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVRLSETIKGFQMILSGELDXLPEQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits (By similarity).
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: UT1_SHEEP
Sequence: MDDNPTAVKLDQGGNQAPQGQGRRRLPKALGYITGDMKEFANWLKDKPQALQFVDWVLRGISQVVFVSNPISGILILVGLLVQNPWCALNGCVGTVVSTLTALLLNQDRSAITAGLQGYNATLVGILMAIYSDKGNYFWWLLFPVSAMSMTCPIFSSALNSVLSKWDLPVFTLPFNMALSMYLSATGHFNPFFPSTLVTPVTSVPNVTWPDLSALQLLKSLPVGVGQIYGCDNPWAGGIFLGAILLSSPLMCLHAAIGSLLGIIAGLSLSAPFENIYAGLWGFNSSLACIAIGGMFMALTWQTHLLALACALFTAYLGASMSHVMAVVGLPSCTWPFCLATLLFLLLTTKNPNIYKMPISKVTYPEENRIFYLQSTKRTVQGPL
What is the function of this protein?
Mediates the transport of urea driven by a concentration gradient across the cell membranes of erythrocytes and the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism (By similarity).  Facilitates water transport in erythrocytes (By similarity).
What are the official names of this protein?
Urea transporter 1, Solute carrier family 14 member 1, Urea transporter B, UT-B, Urea transporter, erythrocyte.
What is the protein family that this protein belongs to?
Belongs to the urea transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Restricted to the basolateral membrane in various portions of the urothelium.
Protein: TBP_METTL
Sequence: MEPEIKIVNVVVSTQIGTDIDLEYAADILDNAEYEPEQFPGLVCRLSDPKVALLIFRSGKLNCTGAKSKEDAEIAIKKIIKELKDAGMDIIDNPEVNVQNMVATADLGIEPNLDDISTLEGTEYEPEQFPGLVYRLSDPKVVVLIFGSGKVVITGLKKKDDAYLALDKILSTLKELEEEYY
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor, aTBP.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: HISZ_GLOVI
Sequence: MYQPPTGVRDLLPLDVSQKLWIEQRLQRVFTRWGYQRIITPTLERMETLQASGSVDLQAILQLRDAEGVSLGLRPDPTPSLARAVATRLADAPLPVRLSYQMNVFRSTTQPQEFYQAGVELIGAGGVLADAEVLLVLAECLAELAPPDWTLILGAVAFTRSWLAQVAEPARHRLRRAMAELDRVAILAEAGIDEAVRSQLLLLFDLRGEPEMVLSKASSLPMSDAQRAELAELETLTGWLRGRSVPVVLDLSLVEAFDYYTGLIFEVSAGGRLIGRGGRYDHLLGSYGKPAPGAGFALNLEALQQVLLPTGKLPGRTVGGGFLVVPDGPDAWEAALAEADKLRCAPGERVEIELLGRTGEEAIAHGRALGAAVVRWVHPDGSTTDCDLAVIQ
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_RHIME
Sequence: MSIAAKDIEPADIPGNLQGGEYSPYHVFSAEEWSRFRADTPLTLTADEVQRLRSLNDPVDLDEVRRIYLSLSRLLSAHVEASQILFRQRTRFLSMSNETKTPFVIGVAGSVAVGKSTTARILAELLARWPSSPKVDLVTTDGFLYPNAVLQRENLMDRKGFPASYDIGALLRFLSAIKAGRPNVKAPTYSHLTYDVIPDQFQVIDRPDILIFEGINVLQSRDLPADGKIVPMVSDFFDFSIYIDAEESLIHSWYVNRFMRLRETAFQSPQSFFHRYATISEDAARAIAEGLWHNINLKNLHQNILPTRPRADLILQKGPNHLTQTVALRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_BRUSU
Sequence: MAQLIDGKKLAEDVVSTVKTETEKLVAATGVVPGIAVVIVGEDPASQVYVASKSRKAKECGFHSVQHDLPETASEQELLNLIEGLNNDPAIHGILVQLPLPGHIDSGRVIQTIAPEKDVDGFHFINVGKLGTGEVETAFVPCTPAGAMIMIERVHGRDLSGLNAVVIGRSNIVGKPMFNLLLAANATVTVAHSRTKDLPAIARNADILVAAVGRPQMVKGDWVKPGATVIDVGINRIPAPERGEGKTRLVGDVDFAEAEKVAGAITPVPGGVGPMTIAMLMANTLTAACRSAGMKKPVF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HISJ_ECOLI
Sequence: MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNSQGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQEIAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIVSYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTGMGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG
What is the function of this protein?
Part of the histidine permease ABC transporter.  Binds histidine.  Interacts with HisQMP and stimulates ATPase activity of HisP, which results in histidine translocation (By similarity).
What are the official names of this protein?
Histidine-binding periplasmic protein, HBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: BPT_JANMA
Sequence: MTHPKELPFSTLQFYATAPYPCSYLDGRQARSQVATPSHLINADVYSELVKSGFRRSGIFTYRPYCDGCQACTPVRIKVADFIPNRSQRRAQAKHSDLQTSVTKLTYLAEHYDLYLRYQTARHAGGGMDQDSREQYAQFLLQSKVNTRLVEFREDDGTLRMVSIIDVLDDGLSSVYTFYDPEPPNASYGTYNILWQIAQAKALQMPYIYLGYWIKESPKMSYKTNFQPLEALQQGEWTPLPVVDPAATR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_SHIB3
Sequence: MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVRDPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRVRFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGRFYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_METC4
Sequence: MNGQNIRIRLKAFDHRILDASTKEIVSTARRTGAQIRGPIPLPTHIEKFTVNRSPHIDKKSREQFEMRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NITR_PSEU2
Sequence: MKEPLKVACVQAAPVFLDLDATVDKTITLMEQAAAAGAGLIAFPETWIPGYPWFLWLDAPAWNMPLVQRYHQQSLVLDSVQARRISDAARHLGLYVVLGYSERNKASLYIGQWIIDDHGETVGVRRKLKATHVERTMFGEGDGASLRTFETPVGVLGALCCWEHLQPLSKYAMYAQNEQIHVAAWPSFSLYRNATSALGPEVNTAASRVYAAEGQCFVLAPCAIVSPEMIEMLCDSDAKRSLLQAGGGHARIFGPDGSDLATPLGEHEEGLLYATLDPAALTLAKVAADPAGHYSRPDVTRLMFNPNPTPCVVDLPDLPISSESIELLRPDIALEV
What is the function of this protein?
Arylacetonitrilase which is capable of hydrolyzing indole-3-acetonitrile (IAN) to the plant hormone indole-3-acetate (IAA), and allows the plant pathogenic bacterium to use IAN as a sole nitrogen source.  Is also able to hydrolyze phenylpropionitrile (PPN), allowing the use of this compound as a sole nitrogen source.  This enzyme may represent an additional mechanism for IAA biosynthesis or may be used to degrade and assimilate aldoximes and nitriles produced during host plant secondary metabolism.
What are the official names of this protein?
Nitrilase, Arylacetonitrilase, Indole-3-acetonitrile hydrolase, IAN hydrolase, Indole-3-acetonitrilase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: LEA17_ORYSJ
Sequence: MASRQDRREARAEADARRAAEEIARARDERVMQAEVDARSAADEIARARADRGAATMGADTAHHAAGGGGILESVQEGAKSFVSAVGRTFGGARDTAAEKTSQTADATRDKLGEYKDYTADKARETNDSVARKTNETADASRDKLGEYKDYTADKTRETKDAVAQKASDASEATKNKLGEYKDALARKTRDAKDTTAQKATEFKDGVKATAQETRDATADTARKAKDATKDTTQTAADKARETAATHDDATDKGQGQGLLGALGNVTGAIKEKLTVSPAATQEHLGGGEERAVKERAAEKAASVYFEEKDRLTRERAAERVDKCVEKCVEGCPDATCAHRHGKM
What is the function of this protein?
Involved in abiotic stress responses.  May function as chaperone and contribute to prevent the formation of damaging protein aggregates.
What are the official names of this protein?
Late embryogenesis abundant protein 17, OsLEA17, Late embryogenesis abundant protein 1, OsLEA3-2.
What is the protein family that this protein belongs to?
Belongs to the LEA type 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TM208_CHICK
Sequence: MAPKGKAGTKGKKQIFEENRETLRFYLRIILGASAVYAAVNLVVFYPAASAWTWLAFAFSSAVYGASYRSMSSMARPAFADDGSLADGGIDLNMEQGWQSECPHPHEPRHLKDVILLTAMVQVLSCFSLYVWYFWLLAPGRALYLLWVNILGPWFTAESSAPGQEPNEKKQRRTGTPPE
What is the function of this protein?
May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
What are the official names of this protein?
Transmembrane protein 208.
What is the protein family that this protein belongs to?
Belongs to the TMEM208 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FLGH_RHILO
Sequence: MIRRTLILCAVAALSGCGTNLREVGKEPSLSPVGSGIDGGNTSALYKYPEPPRAPVKKFSLWDDRQSRLFTDPRALSQGDILTVRIKINDRANFKNQNDRSRTANRKLGFDLSAQWDKWSTAGKGAGALNSATDTTADGEIKRSETLELNVAAIVTDVLPNGNLMITGSQEVRVNAELRVLTIAGIVRPADIGAENTIPYERIAEARISYGGRGRISEIQQPAYGQQVLDQVLPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: ENV_NPVLD
Sequence: MSPLALIVLLAWHATAFKSTDTIEVIPLPHTSGFYYQPINRMQFVEDVWHFIIEVDHGVIFQELDELYRDTLHLLNHTRSSKFVSANCTTNAIIESEINTYILKRILYLVQQHNTIDDKIKANAEGDAPDSRWELNTKDPLAPRRKRGVLNFVGTVDKFLFGVMDSNDARELHDLAKTSNALNEQIKEVTDELVNIAKFEEHKQCLERQRDDLCGYATAKMALITEQLTQLDLLYTNLDRAVDDALDNRINSLIMTPQRLYEEMTNVTVHVPTKLTWPVPLKKTNMHDLINDKIVKTHVFKLERRKLIFILEVPLIDDQNYDVYQVIPIPLCGGDGKCAVIVPDSKYLGVSTNKRNYVRLEDDAPKACKMTSKNLLCFKPKVVHVSSEATLCDIKILLHYENSYENVQRDCDVRVGKFDPEIFHLISDYNNWLYVLQRDTELTMDCADASSASNVIRIAAGTGIIRGRNVTRSCNLMTKSKQLALHQLKNSLFSVSAVPLSTSFNLSAALGDLDRLEIESMKNNADLDHKHLQGATQRLIDLRKRMNNNSVFHGAELEGEASDGWFCWLVGWLNIKCATAEAVVACVVLFLVALLLFRIYRFCCPGTCSAMFSCCRFDALSSVPRRRNKTKSSVIRVNSQLQYLDGGGGGEKSHEETPMVMFNNRARDPNVVFKNI
What is the function of this protein?
Envelope glycoprotein which mediates the fusion of viral and host endosomal membranes leading to virus entry into the host cell.
What are the official names of this protein?
Envelope fusion protein.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: NUOK_MYCTO
Sequence: MNPANYLYLSVLLFTIGASGVLLRRNAIVMFMCVELMLNAVNLAFVTFARMHGHLDAQMIAFFTMVVAACEVVVGLAIIMTIFRTRKSASVDDANLLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTF3_XENUN
Sequence: IQSTSMDQGSLSEDSMNSFIRTFIQAGIWKNKVPKQAARTKDGTQTTAKKTEAEPEATANKDFQLGFQPVVSVDAELLRQQRRFSSPRVLLSENTPLEPPPLYLMEEPMVLNRTSRRKRFAEGKSHRGEYSVCDSESRWVTDKSSAVDIRGHQVTVLGEIRMGPS
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: BECN1_XENLA
Sequence: METSKSSTMQVSFVCQRCSQPLKLDTSFKILDKVTMQELTAPLVTTAAVKPGDIQEVDSNIEETFAENRTDGVSRRLIPPARMMSTESATSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNITENECQNYKRCLEILERMNEDDKEKLEAKLKELAEDEERLIQELEEVERNRELVAKDIEKVREEAERLEQEEARYQKEYSEFKRQQLELDDDLKSVENQMRYAQIQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLQFQRYRLVPFGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGDTGFCLPYRMDVDKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
What is the function of this protein?
Plays a central role in autophagy (By similarity).  Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis (By similarity).  Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity).  Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms (By similarity).  Involved in endocytosis including endosome formation in neuronal cells (By similarity).
What are the official names of this protein?
Beclin-1.
What is the protein family that this protein belongs to?
Belongs to the beclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome.