PharMolix/UniProtQA huggingface dataset:
Protein: S22AG_HUMAN
Sequence: MGSRHFEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWSLEDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESENESKSSKLLLTTNNSGLEKTEAITPRDSGLGE
What is the function of this protein?
High affinity carnitine transporter; the uptake is partially sodium-ion dependent.  Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa.  Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin.  The uptake of TEA is inhibited by various organic cations.  The uptake of doxorubicin is sodium-independent.
What are the official names of this protein?
Solute carrier family 22 member 16, Carnitine transporter 2, CT2, Fly-like putative transporter 2, FLIPT2, Flipt 2, Organic cation transporter OKB1, Organic cation/carnitine transporter 6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Protein: GET3_DANRE
Sequence: MAASVEDEFEDAPDVEPLEPTLKNIIEQKSLKWIFVGGKGGVGKTTCSCSLAVQLAAVRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETERLIQELAKCRIDTHNIIVNQLVFPDNERPCKMCEARHKIQSKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSKQLLEPYSPPKK
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1/WRB and CAMLG/GET2, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-CAMLG receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Guided entry of tail-anchored proteins factor 3, ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: PYRF_SALPK
Sequence: MTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLKVGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASGGARMMAAARDALAPFGKDAPLLIAVTVLTSMETSDLRDLGVTLSPAEHAERLARLTQQCGLDGVVCSAQEAVRFKQVFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKDINASLKREA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CG121_USTMA
Sequence: MESISLPWTLPEPLQQVHLAHFSNLDPATQSAAIIDRIISASRLPSASPEQAQQADEERVKLDFAFLDPTKLCSKLHLLSAVTQAAVVCARSWDDDRQVFREGEASIGGMKSKTPHSEVIYMLNPGNNVGESLKRFGLSPTSSSLLLVKFSSPTADKQAILQSMIDLVSPSNLTSPPTAEAHTPIDIDHAIRYGSYPTTPSTTAQVTDWKQLNKIYKLQIPSTLLNNKQDNQWYEKYQDIICTSVAMKLVAA
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.  CGI121 is not required for tRNA modification (By similarity).
What are the official names of this protein?
EKC/KEOPS complex subunit CGI121.
What is the protein family that this protein belongs to?
Belongs to the CGI121/TPRKB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: RSMG_BRUMB
Sequence: MSADIRFDSLKTIVPAVSRETADRLIAFEDLFRKWSKAINLASPSTLADLWNRHILDSAQLFPLAKEATRWLDIGSGGGFPGIVTACFLAERSGGCIDLVESAGKKAAFLRTAAGHLHVPARVHSARIESMWEKIETPQVVTARALASLGDLFTLAEPWLSDGAKALFQKGRDYQREIDESRVGWSFDLVKHPSAIDQASVILEISNLRRKTD
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_HELPY
Sequence: MRVKTGVVRRRRHKKVLKLARGFYSGRRKHFRKAKEQLERSMYYAFRDRKQKKREFRSLWVVRINAACRMHNTSYSRFMHALKVANIELDRKVLADMAMNDMQAFTSVLESVKEHL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RS9_CHLP8
Sequence: MKEVIDTVGRRKTSVARVFMSPGKGKIVVNKLPVEEYFKDEFKRSQALKPLVTAEKQDEFDIKVNVKGGGLTGQSGAVCLAIARALVEFDESIRPTLRTERLLTRDPRMVERKKYGKKKARKSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RL9_MYCLE
Sequence: MKLILTADVDHLGSVGDTVEVKDGYGRNFLLPHGLAIVASRGAQRQADEIRRARETKAMRDREHANEIKVAIEALGSVSLPMKTVADSGKLFGSVTAGDVVAAIKKAGGPNLDKRIVRLPKTHIKAVGTHPVSVHLHPEVDVVVLLDVVAAR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: APT_SHESM
Sequence: MAMNTETLSLIKQSIKTIPNYPKEGILFRDVTSLLENAAAYKATIDLLVEQYRNKGFTKIVGTEARGFLFGAPLALELGIGFVPVRKPGKLPRATISQSYELEYGHDSLEIHTDAITANDKVLVVDDLLATGGTIEATVKLIRQLGGEVQDAAFVISLPDLGGEARLTALGLELVKLCEFEGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORC_PYRAB
Sequence: MIEIRFHGRGGQGAVTAANILAEAAFIEGKYVQAFPFFGVERRGAPVTAFTRIDEKPIRIKTQIYEPDVVVVLDPSLLETVDVTAGLKEDGIVIVNTEKSKEEVLEKLKRKPKKLALVDATTIALETLGLPITNTAILGAVAKATGLVKIESVETAIKDTFSGELGEKNAKAAREAFEKTQIFEV
What are the official names of this protein?
Pyruvate/ketoisovalerate oxidoreductases common subunit gamma.
Protein: KDPC_BACMK
Sequence: MAKKQSILSPIIRITFTFLVLCGLVYPLIVTGIAQAVMKDNADGSLIYNDKDEVVGSKLIGQNFTDPRYFHGRVSSIEYKAEASGSNNYAPSNPDLAKRVEKSIDDWKKQNRAIPVTEVPIDLVTNSGSGLDPDISPKAASVQVDRISKLTNIPKEKLDQLIKDQTEGAALGLFGEDRVNVLKLNLELQKLMK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SH2D3_HUMAN
Sequence: MTEGTKKTSKKFKFFKFKGFGSLSNLPRSFTLRRSSASISRQSHLEPDTFEATQDDMVTVPKSPPAYARSSDMYSHMGTMPRPSIKKAQNSQAARQAQEAGPKPNLVPGGVPDPPGLEAAKEVMVKATGPLEDTPAMEPNPSAVEVDPIRKPEVPTGDVEEERPPRDVHSERAAGEPEAGSDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGSSKPASPVSPSGPKGSHMKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAPEGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEPAVRSSEL
What is the function of this protein?
May be involved in the BCAR1/CAS-mediated JNK activation pathway.
What are the official names of this protein?
SH2 domain-containing protein 3C, Cas/HEF1-associated signal transducer, Chat-H, Novel SH2-containing protein 3, SH2 domain-containing Eph receptor-binding protein 1, SHEP1.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Cell projection, axon. Cell projection, ruffle membrane. Note=Associated with the membrane when EGF-stimulated (By similarity). Expressed at the cortical actin ring in B cells (By similarity). SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane; Peripheral membrane protein.
Protein: YNF8_SCHPO
Sequence: MASIRQAFVKSLRFYDIGYNATDPVFRGIYHEKLKHPDDFDSIISRAKAVGVEKMMITGDNVENSEEALNLATNYECFTSTVGVHPCQAQCFLRHSEGPEDYLVKLEALANKGKASGKVVAFGEFGLDYDRLHYAPADVQKMYFEEQLKVAVRVQLPLFLHSRNAENDFFAILEKYLPELPKKGVVHSFTGSIDEMRRCIEHGLYVGVNGCSLKTEENLEVVRAIPLEKMLLETDAPWCEVRPSHAGHQFLKTKLPFDSCKKERFKEGCMIRGRNEPCNTYIVAEIVAALKDISLEELSEQIWENSINLLSK
What is the function of this protein?
Has both endo- and exonuclease activities.  Incises double-stranded DNA without obvious specificity via its endonuclease activity and excises the DNA from the 3'-to 5'-end by its exonuclease activity.  May have a role in apoptosis (By similarity).
What are the official names of this protein?
Deoxyribonuclease Tat-D.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NADK_SULIY
Sequence: MRVKIVSKPTSQLNNIIEKIKNISTKLGFEVVDKDFDYVIAVGGDGTLLRAVKQNKPVIAVKAGRRGLLMDVPVDKFEEALLRLKKGDYEEEEYMLLEMIYNDKVELGFNEVGILYDRPEAIKVGISFDTERVSVEGDGVLVSTPQGSSGWGMSATNSLLYKDLSAIEIIFVNPIFYYLRSVVIPPKPLTLRLEDKGYPQTARAVVDGEVVTLIKTNQEITVRVSQRKAKILRFFKLDLIGEVLHAYHI
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_STRPD
Sequence: MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEAAFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: DEN2D_MOUSE
Sequence: MEGQGVGRTLRLLRNRLPRLRAGQSQNNPGEAVTEPERIQEHSPSSFAGGQHFFEYLLVVSLKKKRLGDDYEPTITYQFPKRENLLRGQQEEEDRLLSAIPLFCFPDGNEWAPLTEYPRETFSFVLTNVDGSRKIGYCRRLLPAGPGPQLPKVYCIISCIGCFGLFSKILDEVEKRHQISMAVIYPFMQGLREAAFPAPGKTVTLKSFIPDSGTEFISLTRPLDSHLEHVDFSVLLHCLHLEQIIQIFASAVLERKIIFLAEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRFLQEVMDSPMEEVLLVNLCEGTFLLSVGDEKDILPPKLQDDILDSLGQGINELKTSEQINEHVSGPFVQFFVKTVGHYASYIKREASGQGHFQERSFCKAVTSKTKRRFVKKFVKTQLFSLFIQEAEKSRNPPAGYFQKKILEYEEQKKQKKSRERL
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity).
What are the official names of this protein?
DENN domain-containing protein 2D.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_DECAR
Sequence: MLILNQRTQQLATDSVALAYDERKRSRLKVTLASGAEAGIFLERGDHLHGGDKLAAEDGSAVVEILAAPEKLIEAIADSPLLFARAAYHLGNRHVPVQILPTENGGKLRFQTDHVLAEMVRGLGCSVSDAEAPFQPESGAYGGGHHHGDESATDLHNPGHGPHRSVPKIHEFKPR
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPNS2_HUMAN
Sequence: MMCLECASAAAGGAEEEEADAERRRRRRGAQRGAGGSGCCGARGAGGAGVSAAGDEVQTLSGSVRRAPTGPPGTPGTPGCAATAKGPGAQQPKPASLGRGRGAAAAILSLGNVLNYLDRYTVAGVLLDIQQHFGVKDRGAGLLQSVFICSFMVAAPIFGYLGDRFNRKVILSCGIFFWSAVTFSSSFIPQQYFWLLVLSRGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQAAGDWHWALRVSPVLGMITGTLILILVPATKRGHADQLGDQLKARTSWLRDMKALIRNRSYVFSSLATSAVSFATGALGMWIPLYLHRAQVVQKTAETCNSPPCGAKDSLIFGAITCFTGFLGVVTGAGATRWCRLKTQRADPLVCAVGMLGSAIFICLIFVAAKSSIVGAYICIFVGETLLFSNWAITADILMYVVIPTRRATAVALQSFTSHLLGDAGSPYLIGFISDLIRQSTKDSPLWEFLSLGYALMLCPFVVVLGGMFFLATALFFVSDRARAEQQVNQLAMPPASVKV
What is the function of this protein?
Lipid transporter that specifically mediates export of sphingosine-1-phosphate (sphing-4-enine 1-phosphate, S1P) and sphinganine-1-phosphate in the lymph, thereby playing a role in lymphocyte trafficking (PubMed:19074308, PubMed:23180825, PubMed:21084291).  S1P is a bioactive signaling molecule that regulates many physiological processes important for the development and for the immune system (PubMed:19074308, PubMed:23180825).  Regulates levels of S1P and the S1P gradient that exists between the high circulating concentrations of S1P and low tissue levels that control lymphocyte trafficking (PubMed:19074308, PubMed:23180825).  Required for the egress of T-cells from lymph nodes during an immune response by mediating S1P secretion, which generates a gradient that enables activated T-cells to access lymph (By similarity).  Also required for the egress of immature B-cells from the bone marrow (By similarity).  In contrast, not involved in S1P release from red blood cells (By similarity).  Involved in auditory function (PubMed:30973865).  S1P release in the inner ear is required for maintenance of the endocochlear potential in the cochlea (By similarity).  In addition to export, also able to mediate S1P import (By similarity).
What are the official names of this protein?
Sphingosine-1-phosphate transporter SPNS2, Protein spinster homolog 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Protein: SERC_LACLS
Sequence: MIYNFGAGPSVLPKEVLKKVQEELLDFEKSGMSVMEISHRSKSFQEVIDEAQSNLRDLMSIPQNYKILFLQGGASTQFSMIPMNLALGKKAYYAISGAFGKKAYDEAVKLSQTLDFEAISLGSTQSEHYNHLLKIDKSKVDEKMAAYLHITTNNTIEGTTIFPENLPEVNSVPLIADMSSNILAVDYDVSKFGLIYAGAQKNLGIAGLTIVIIREDLLNQKESLSSMMDYRILAQNGSMYNTPPTFAIYLAGLVFKWVKEQGGVKKLEAINRQKARMLYDLIDQSDFYQSPVLNEAERSICNVVFTSPSKELDALFVQKAEEKGFKSIKGHRSVGGMRASIYNAFPIEGVLELVKFMKEFEEENK
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKB_VIBVY
Sequence: MIERGKYQSLTMVNWNGFFARTFDIDGLVTTLSGGNGAGKSTTMAAFITALIPDQSLLHFRNTTEAGSSQASRDKGLYGKLQPGACYAALDVVNSRNQRLLFAVKLQQVAGRDKKVDIKPFVIQGLPSHVKPTDVLIESVSATQARVRQINEVKESVAQYEGVQFKSFSSIVDYHAQMFEFGVIPKKLRNSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPQNGGVKKAFQDMESALRENRMTLEAIKTTQADRDLFKHLITESTNYVAADYMRHANERHKKLEQSLSLRSELFSSRETLIEQNRLLNQVQQELEMLVESESALEQDYQGASDHLQLVQNALRQQEKIERYQEDLEELNERLEEQSMVVEEAQERVLMAEEQSTVAENEVDSLKTQLADYQQALDVQQTRALQYQQAVQALEKAKVLLSDSTLTAESAQALVAQLTQSEAEQTQALLALKHKLDMSSAAAQQFENALKLVHSIAGQVERAEASRYAKAAIQQARSAQQVVQNENQWRAQHRDLERSLNQQNQAQALVAEYQKAHQVTLDDEVMFEQERERHHAQLDSLEIALEENRELRSEQRRQEQDLQSDITQLQAIAPKWIAANDALEKLREQSGAELADSQSVMSQMQQVLEQEKQLSQAKDKLAERRSQLESEIERLASPGGSNDPRLKGLADTLGGVLLSEIYDDITIDDAPYFSAMYGPARHAIVVSDLSGIEEKLVELDDCPEDLYIIEGDVDAFDDSSIKAEELEGAVCVRLNDRQMRYSRFPVIPLFGRAAREQRLELLRSEREEVVEKHAKAAFDAQKMQRLFQAFNQFVAEHIQVAFAADPEQALVIARDKRNQLTRTLAELEAKEQQMRSQIQNSKQALTMLDKLAPMMAVISDDTIGERFAELEEKIAQLADAKQFLNAHAKAVEQLESQLAVLDADPEQFDALEAQYQSADSQLQALKKQIFALSDLVERRHYFAYADSVDLLSKSSELSEQLKAKLVEAERTRSRYRDELKQQQEQMNQYNQVLASLKSSYQAKLETVQEFKQELAEFGVSADEGALERAIRRRDELHERLHTSRSRKSEYERTLTSTELGMKELAKRLKKVQKEYVELRTFVVAAKAGWCSVLRLARENDVERRLHKRELAYLSAGELRSMSDKSLGALRLAVANNDDLRDALRLSEDNARPERKVLFYIAVYQHLRERIRQDIIHTDDPVEAIEEMEVELARLTEELTMRENRLAISSESVASIIKKTIQREQNRIRMLNQGLSNISFGQVKGVRLNVKVRESHEVLLNGLATQQEQHKDLFETARYTFSEAMAKLFQRVNPHIDMGQRSPQVLGEELLDYRNYLELSIEVNRGSDGWLQAESGALSTGEAIGTGQSILLMVVQSWEEESRRLRSKDIVPCRLLFLDEAARLDAKSISTLFELCDRLDMQLLIAAPENISPEKGTTYKLVRKVFKDHEHVHVVGLRGFGQEQKPKSEAQQMIEEFEA
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: FENR_STRTD
Sequence: MAEEKIYDITIIGGGPVGLWAAFYAGLRGMTVNIIESLSELGGQPAILYPEKKIYDIPAFPQTTGAELIENLLIQLKRFEDRVSIHLKEEVQTFKKTDGIFTIATSKGQHLSKAIVIACGNGAFAPRPLGVDNEEDFANNNLLYNVHSLDQFAGKKVVIAGGGDSAVDWANHLDGVAESVTLIHRRDAFRAHEHSVELLYQSSVNVMTPYVPLEIKGENGHAQSLTVQRVKSDEVVELPIDALIVSFGFSTNNKNLRNWNVDYKRSSITVNAQFETSQEGVYAIGGAAEYDGKIDLIAVGMGEAPIAINQAIQYIEPDGKNRPVHSTSLIEE
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: S39A6_MOUSE
Sequence: MATDLSVIMILTFALWVTSPLHELQSTAAFSQTTEKINSNWEPGVNVDLAVTMQRHHLQQLFYRYGENDSLSVEGFRKLLQNIGIDKIKRVHIHHDHEHHADHEHHSDHEHHSDHEHHSDHEHHSDHEHHSDHEHHSHRSHTVAGKNNRKAFCPDLDSDNSGKNPRTSLGKGSRPAEHMNGRRNIKESASSSEVTSAVYNAVSEGTRFVETIETPKPGRRTKDVNPSTPPSITEKSRVGRLSRLARKKSNESVSEPRKSFMYSRNTNDNIQECFNTTKLLTSHGMSIQALLNATEFNYLCPAIINQIDARACLIHTASEKKAEIPPKTYSLQIAWLGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSFLVALAVGTLSGDALLHLLPHSHASHQHSHSHEEPAMEMKRGPLFSHLSAQNIEESSYFDSTWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDEDVESKKQLSKYDSQLSSNEEKVDPGERPESYLRADSQEPSPFDSQQPTMLEEEEVMIAHAHPQEVYNEYVPRGCKNKCHSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGIATLAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCSRWGYFFLQNAGILLGFGIMLLISIFEHKIVFRINF
What is the function of this protein?
May act as a zinc-influx transporter.
What are the official names of this protein?
Zinc transporter ZIP6, Endoplasmic reticulum membrane-linked protein, Ermelin, Solute carrier family 39 member 6, Zrt- and Irt-like protein 6, ZIP-6.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Found in the endoplasmic reticulum when overexpressed.
Protein: SPCS2_PONAB
Sequence: MAAAAAQGGRSGGIGGCIGAGGASNCGTGSGRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLAIERKIK
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 2, Microsomal signal peptidase 25 kDa subunit, SPase 25 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ADEC_META3
Sequence: MIILKNANIVGVRNGTIVNGSIGINGDKIAFVDYIDYNNHNNDNIYNKNENTQEIRRKQRFNTRSEAPVKIIDLKGKFVCPTFIDAHIHIESSHITPSEFEKYALKYGVSKVIIDPHEIANVVGVNGIKFMLNDAKLLDVYCMVPSCVPATELETNGAPITSKDIEELFKQNNYRILGLGEVMNYIGVINKDKNIIDKINMAKKYNKLIDGHAPQLTREDLINYVNMGIMSDHECTTEDEALEKLQLGLKLMVREGTASKNIYLLKIIDILKRKGTYNKLFKNIMLVSDDISVKDLKEGYLINTLKKAVKYVSPIEAIQMITINPANYFGLDMEIKPDNYADLIIFDDLEEFKINSVIIKGKFLNELNKYNKNNNIKNNKNNNDNLINKSINYNYKTENDFLIDGIDGGGAPISTNSKVRIIEPIGSSLITNEIMLNIDDAKTKLKNNEINRIFVLERHRNTNKIGKGLIKYLKTGTIASSYAHDSHNVIVIGNNLKDIAIAVNHLKDMGGGFVAVKDGKIIEQVKLNMGGIMGADGEYIYKKINDIENKTKNWSIIENNNLFLSMSFLSLSVIPNLKITDFGLIKNNKIVNLVEL
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.