PharMolix/UniProtQA huggingface dataset:
Protein: PRIL_METAR
Sequence: MDAVGFAKYPFTQEALSYVRDRNYSMEDILQKPAYGQVRLRAKKRVLNSIKGDVQADDLLPDPERELLSYPVARMLVAMTEDQYLMKRFALWESKRAYTLLLDESDTGLMDVGRDFGITARAKDREFIIHFTDYLRYAAGLRNLEWKLINRKVVAGMVYVSRETFTRLLEEAVREKIQAGFGAKVPAEMKPVLEPYLAEIRESLDKLKSEKGLSGDGEVTQDSFPPCMKNLLADLQKGINLPHTARFALTSFLANIGLDKDAIMDLYRMAPDFREDLTHYQVQHITGGSGTEYTCPGCKTMMTYGNCIGKNKLCEYVTHPLSYYRKSQRRRAKEMAAAQAFKGSKDKAVDTVAENVHVETGNSPGN
What is the function of this protein?
Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase large subunit PriL.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase large subunit family.
Protein: RS12_LACP3
Sequence: MPTINQLVRQGRKSISTKSDSPALNFGYNSKKKSLTNNPAPQKRGVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVDGRMQGRSKYGAKRPKKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DCUP_ANADE
Sequence: MTHRFLAACRREPVDRVPVWMMRQAGRYQPSYRAVRQKVSFLELCRSPELIAQVTVAPIDEFGFDAAILFSDILVHLPAMGLDLTFEKGEKGKGDGGPKIGNPVRTRADVDALRVPVPKKDLPYVLDGVRAIRTALADRVPLIGFVGGPFTVASYAVEGGSQGFTRLKTMLYAEPATAHALFEKLTQAAIVQIEEQVAAGAQAAQIFESWLGELAREDLEEFSFPYLARIAEAVRKTGVPSIIFSTGTTAHLERMAKLGYDVVSVDWRIPIDEARARLPGVAVQGNYDSTLLLGPREVAVARAQQLLRAAGPTPGYIFNLGHGIQVGTPTENVKAVVDAVHAFGWK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_BORPA
Sequence: MTTPIPLARGWLPAAPSTLDPLRKYWLFRPGALTAGLRQLGHVRLRVLAEYPTGAPRDEADGMRIAAQSPVWVREVLMSIDGVDSVVARSLTPLRASHGVWQGMRRLLTRPLADMLYHDPGIHRSVFVCRRLAAGVPFHATAIARAPAGGPEPALWARRSAFWRAGQPLLVAECFLPAFWSLARAPVAPR
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_MACGI
Sequence: VHLTAEEKNAITSLWGKVAIEQTGGEALGRLLIVYPWTSRFFDHFGDLSNAKAVMANPKVLAHGAKVLVAFGDAIKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNIIVICLAEHFGKEFTIDTQVAWQKLVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: G6PI_LEPCP
Sequence: MNTPRCDQTAAWAALAAHHQGAGRQFDLRTAFGADAGRFDAFSLQAPEVFADLSKNHWDATTRGLLLGLARQCQIESRRDAMLAGEPINHTEGRAVLHTALRAPRGAAPFSDDVHGVLDAMLAYVEQVRDTATSGIKHVVNIGIGGSDLGPQMVVPALDAYAQRGLQLHFVSNVDGHDIAPVLRDLNPRETLVIVASKTFTTQETMANAQVARTWFLAGYGEGGEAAIAKHFAASTTNVAAAAKFGITTTFGFWDWVGGRYSLWSAIGLPIALAVGAENFRALLAGAHAMDRHFATAPLESNLPIQLGLLDVWYRNFLGYTSRSIAPYHQGLRRLPAYLQQLEMESNGKCVDLDGASLPYGTCPVVWGEAGTNGQHAYFQMLHQGTDVIPVEFIAVKTPNHGPDVADELKAGLADQHVKLLANCLAQSQALMLGKTTDDALTDKAPTASTALDALTVARHRTFPGNRPSSTLVLDRLSPASLGALIALYEHRVYTSGALWGINSFDQWGVELGKALCNQLLPRFASGESAGLDASTAGLLARLRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_THIDA
Sequence: MIKQRTLKTPVKATGVGLHSGVKVEMTLRPAAPDSGIVFRRVDLEPPAELKADPYLVTDTRLCSMLESGAAKVSTVEHLMSALAGLGIDNLLVDLTGPEIPIMDGSSAPFVFLLQSAGIVEQNAAKRYVRITRPIEVRDGDKWARFVPHHGFKIEFTIDFKHPVFDKSGKTVTIDFADTAYTKEVARARTFGFMHEVEYLRNQGLALGGSLDNAIVMDEYRVLNQDGLRYDDEFVKHKVLDAIGDLYLLGHPIIGAFEAYKSGHALNNALLRELLQHREAWEFVSFEHDEDVPSAFLRLHPLAA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: CYNS_PSEAE
Sequence: MQHSQVSPNARQQLAETVVLNKARLGLSWQDLADGTGLALTFVTAALLGQHALPEAAARKVAAQLGLDDDAVLLLQSIPLRGSIPGGIPSDPTIYRFYEMLQVYGSTLKALVHEQFGDGIISAINFKLDIKKVEDPEGGSRAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: PAGP_SHIF8
Sequence: MNVSKYVAIFSFVFIQLISVGKVFANADERMTTFRENIAQTWQQPEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGLSRWDEKGNWHGLYAMAFKDSWNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGPVTFQMTYIPGTYNNGNVYFAWMRFQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: GDNF_DANRE
Sequence: MKLWDILATCLLLLSSVSTRPLFHKLQPSKRAVVRSESPALDPIIDSQPETSNPKQASMEEQYDLTGLYPEQFEDVMDFIEATLGRLRRSSDVEPQMKRDRVRQKAAANTEKSGGRGRGERKRSRGRARSRDDRVKGQGRGCLLKEIHLNVTDLDLGYRTKEELIFRYCSGPCHDAETNYDKILNNLTHNKKLDKDTPSRTCCRPIAFDDDISFLDDSLEYHTLKKHSAKKCACV
What is the function of this protein?
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake (By similarity).  Essential for the development of the enteric nervous system, but appears dispensable for the development of the kidney and primary motor neuron.
What are the official names of this protein?
Glial cell line-derived neurotrophic factor, zGDNF.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family. GDNF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CBID_BRUAB
Sequence: MNDETTPANKNPEKAELRCGWTTGACATAATKAALTALITGEFPDPVGIILPKGEVPYFQLAYEGLGEGYAMAGIVKDAGDDPDVTHGATIISTVYPAPPGTGIIFRAGEGVGTVTREGLAIPPGEAAINPVPRRMMTEICEAICAEYGLPADLVITISVPGGEEIAQKTWNPRLGIIGGISILGTTGVVHPFSCSAWIHSIHRGIDVARAAGQKHVLGATGSTSEDAAQALYNLPDFAILDMGDFAGGVLKYLREHPIDRLTIAGGFAKLTKLAQGALDLHSSRSQVDKGFLWQIAERAGAPAGMKERILLANTAMEVLELTQSIGIDIAGPIALEARQTALKTLRGAPVEVEIIVTDRKGNILARV
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: ACPS_PARL1
Sequence: MIIGIGNDIIDIRRVQKTLDRFGDRFIERIFTEVEKAKSEGRRMRAASYAKRFAAKEACSKALGTGMRRGVFWKDMGVVNLRGGQPTMALTGGALERLKEMTPEGTEAVIHLTITDDHPQAQAFVIISVVPKP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH_RICBR
Sequence: MAEFTPITIAYGDGIGPEIMEAVLYILRKAEARIRLETIEVGEKLYVKHYSSGISEQSWESIERTGVILKAPITTPQGGGYKSLNVTIRKTLQLFANIRPSVSFYPFTKTLHPNLNLTIIRENEEDLYAGIEYRQTHNMYESVKLISRTGCEKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGIFHKVFNEIAKEYPQINNEHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGSANIGEHYAMFEAVHGSAPDIAGQDIANPSGLLNAAIMMLVHIGQGDIATLIENAWKKTIEDGMHTADIYNKDHSTKKVGTKEFAEEVVKRLGQKPEKLAKADYPLVTKKQESNTTYKINTKEVKKLVGTDIFVGMNVASAHDIADKVNKLDIGNFELKTISSKGLKLWPRDTRFETISDHWCCRFMAKDGVELKHLDITKLLETLSKANIDFIKVENLFEFDGAAGYSLAQGE
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: MPP8_HUMAN
Sequence: MEQVAEGARVTAVPVSAADSTEELAEVEEGVGVVGEDNDAAARGAEAFGDSEEDGEDVFEVEKILDMKTEGGKVLYKVRWKGYTSDDDTWEPEIHLEDCKEVLLEFRKKIAENKAKAVRKDIQRLSLNNDIFEANSDSDQQSETKEDTSPKKKKKKLRQREEKSPDDLKKKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEELKESKKPKKDEVKETKELKKVKKGEIRDLKTKTREDPKENRKTKKEKFVESQVESESSVLNDSPFPEDDSEGLHSDSREEKQNTKSARERAGQDMGLEHGFEKPLDSAMSAEEDTDVRGRRKKKTPRKAEDTRENRKLENKNAFLEKKTVPKKQRNQDRSKSAAELEKLMPVSAQTPKGRRLSGEERGLWSTDSAEEDKETKRNESKEKYQKRHDSDKEEKGRKEPKGLKTLKEIRNAFDLFKLTPEEKNDVSENNRKREEIPLDFKTIDDHKTKENKQSLKERRNTRDETDTWAYIAAEGDQEVLDSVCQADENSDGRQQILSLGMDLQLEWMKLEDFQKHLDGKDENFAATDAIPSNVLRDAVKNGDYITVKVALNSNEEYNLDQEDSSGMTLVMLAAAGGQDDLLRLLITKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAFVNVQQSNGETALMKACKRGNSDIVRLVIECGADCNILSKHQNSALHFAKQSNNVLVYDLLKNHLETLSRVAEETIKDYFEARLALLEPVFPIACHRLCEGPDFSTDFNYKPPQNIPEGSGILLFIFHANFLGKEVIARLCGPCSVQAVVLNDKFQLPVFLDSHFVYSFSPVAGPNKLFIRLTEAPSAKVKLLIGAYRVQLQ
What is the function of this protein?
Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416).  Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2 (PubMed:26022416, PubMed:28581500).  Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592).  Mediates down-regulation of CDH1 expression (PubMed:20871592).  Also represses L1 retrotransposons in collaboration with MORC2 and, probably, SETDB1, the silencing is dependent of repressive epigenetic modifications, such as H3K9me3 mark.  Silencing events often occur within introns of transcriptionally active genes, and lead to the down-regulation of host gene expression (PubMed:29211708).  The HUSH complex is also involved in the silencing of unintegrated retroviral DNA by being recruited by ZNF638: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed (PubMed:30487602).
What are the official names of this protein?
M-phase phosphoprotein 8, Two hybrid-associated protein 3 with RanBPM, Twa3.
Protein: TPIS_DROME
Sequence: MSRKFCVGGNWKMNGDQKSIAEIAKTLSSAALDPNTEVVIGCPAIYLMYARNLLPCELGLAGQNAYKVAKGAFTGEISPAMLKDIGADWVILGHSERRAIFGESDALIAEKAEHALAEGLKVIACIGETLEEREAGKTNEVVARQMCAYAQKIKDWKNVVVAYEPVWAIGTGQTATPDQAQEVHAFLRQWLSDNISKEVSASLRIQYGGSVTAANAKELAKKPDIDGFLVGGASLKPEFVDIINARQ
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: RS15_ROSDO
Sequence: MSITAEEKARVMKEFATKEGDTGSPEVQVAILSSRIATLTEHFKTHKKDNHGRRGLLKMVATRRKLLDYTKAKDEARYQDLIKRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TPIS_HAHCH
Sequence: MRKKLIAGNWKSNGSLERNKALLEGIVNAKALGSVDVVVCPPFPYLQSVESAVSDSMIELGSQNCSATEDGAYTGEVSAKMCADMKCSWVILGHSERRALYAENDEVIACKVKRAVESGLAPILCVGETLADRESGRAEEVTLKQLDAVFMSVQPDDSWVVAYEPVWAIGTGKTASPEDAQSMHKALRNNIRKHFPQIADKIRILYGGSVKSSNAKELFSMPDVDGALVGGASLVSEEFVSIIEAAVE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKT2_VIBPA
Sequence: MDRKYLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPSNPEWADRDRFVLSNGHGSMLIYSLLHLSGYELSIDDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAMAEKALAAQFNKEGHDIVDHFTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKADPRPTLICTKTIIGFGSPNKSGSHDCHGAPLGAEEIAATRKELGWEHGPFEIPQEVYAEWSAKETGAAKEAAWNEKFAAYEAAYPELAAEFKRRVNGELPAEWEEKASQIIADLQANPANIASRKASQNALEAFGALLPEFMGGSADLAPSNLTMWSGSKSLEANDFSGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKIQNIQVYTHDSIGLGEDGPTHQPVEQIASLRLTPNMNTWRPCDQVESAVAWKLAIERKDAPTALIFSRQNLAQQPRSAEQVADIAKGGYILKDSEGKPELILIATGSEVELAVKAAEQLTAEGKKVRVVSMPSTDAFDKQDADYREAVLPSDVTARIAIEAGIADFWYKYVGFDGRIIGMTTFGESAPADQLFEMFGFTVENVVNTAKELLA
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase 2, TK 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: PDXH_PSEF5
Sequence: MTQSLADMRRDYTRDGLSEAQAPAEPFALFHQWFADAVKTEQPPVEANAMTVATVDTDGRPHCRILLLKGLDEQGFTFFTNYESAKGQQLAARPFAAMTFFWPTLERQVRIEGRVVKVTPQESDAYYQVRPLGSRLGAWASPQSRVIADRDELQELLKATEARFSDSQPDCPEHWGGYRLLPERIEFWQGRPSRLHDRLNYRLQGQEWVRERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: SPSA2_ORYSJ
Sequence: MAGNDNWINSYLDAILDAGKAAIGGDRPSLLLRERGHFSPARYFVEEVITGYDETDLYKTWLRANAMRSPQERNTRLENMTWRIWNLARKKKEFEKEEACRLLKRQPEAEKLRTDTNADMSEDLFEGEKGEDAGDPSVAYGDSTTGSSPKTSSIDKLYIVLISLHGLVRGENMELGRDSDTGGQVKYVVELAKALSSSPGVYRVDLLTRQILAPNFDRSYGEPTEMLVSTSFKNSKQEKGENSGAYIIRIPFGPKDKYLAKEHLWPFIQEFVDGALGHIVRMSKTIGEEIGCGHPVWPAVIHGHYASAGIAAALLSGSLNIPMAFTGHFLGKDKLEGLLKQGRHSREQINMTYKIMCRIEAEELSLDASEIVIASTRQEIEEQWNLYDGFEVILARKLRARVKRGANCYGRYMPRMVIIPPGVEFGHIIHDFEMDGEEENPCPASEDPPIWSQIMRFFTNPRKPMILAVARPYPEKNITSLVKAFGECRPLRELANLTLIMGNREAISKMNNMSAAVLTSVLTLIDEYDLYGQVAYPKHHKHSEVPDIYRLAARTKGAFVNVAYFEQFGVTLIEAAMNGLPIIATKNGAPVEINQVLNNGLLVDPHDQNAIADALYKLLSDKQLWSRCRENGLKNIHQFSWPEHCKNYLSRILTLGPRSPAIGGKQEQKAPISGRKHIIVISVDSVNKEDLVRIIRNTIEVTRTEKMSGSTGFVLSTSLTISEIRSLLVSAGMLPTVFDAFICNSGSNIYYPLYSGDTPSSSQVTPAIDQNHQAHIEYRWGGEGLRKYLVKWATSVVERKGRIERQIIFEDPEHSSTYCLAFRVVNPNHLPPLKELRKLMRIQSLRCNALYNHSATRLSVVPIHASRSQALRYLCIRWGIELPNVAVLVGESGDSDYEELLGGLHRTVILKGEFNIPANRIHTVRRYPLQDVVALDSSNIIGIEGYSTDDMKSALQQIGVLTQ
What is the function of this protein?
Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate.  Involved in the regulation of carbon partitioning in the leaves of plants.  May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf.  Plays a role for sucrose availability that is essential for plant growth and fiber elongation (By similarity).
What are the official names of this protein?
Probable sucrose-phosphate synthase 2, Sucrose phosphate synthase 2F, OsSPS2F, UDP-glucose-fructose-phosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family.
Protein: MSRA_ACIC5
Sequence: MAKATFGAGCFWGVEASFRQLHGVQDVAAGYEGGKLDNPTYRDVCTDLTGHAEVVEIDFNPDEIRFEQLLEAFFGLHDPTQLNRQGPDWGTQYRSVIFYHSPEQQTVAQAFIDRLTAEKRFPRPIVTQVVPAATFWRAEEYHQRYLEKRGLATCHI
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: G6PI_XANCI
Sequence: MTQTNGFDALHAHAQRLRGAAIPALLAAEPERPTQYARQVGPLYFNFARQKYDRAALDALFAIARERDLSGAFQRLFRGEQVNVTEQRAALHTALRGDLTDAPVASEAYATAEEVRQRMGSLIQQLEATDVTDIVSVGIGGSDLGPRLVADALRAPSGARFRVHFVSNVDGAAMQRTLATLDPARTAGILISKTFGTQETLLNGSILHAWLGGSERLYAVSANPERAAKAFDIAPGRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQFDAHVLNTPLEENVAVLHGLTAVWNRNLLGSATHAVMTYDQRLALLPAYLQQLVMESLGKRVKLDGSAVDSDTVSVWWGGAGTDVQHSFFQALHQGTSVVPADFIGTVHNDDPYAENHTALMANVLAQTEALANGQDSSDPHRSYPGGRPSTVILLDALTPQALGALISMYEHSVYVQSVMWGINAFDQFGVELGKQLASQLLPALKGESVDVADPVTRELLNKLRG
What is the function of this protein?
Required for pathogenicity.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_PSESM
Sequence: MNLHEYQGKQLFAEYGLPVSKGYAVDTPEAAAEACDKIGGTEWVVKAQVHAGGRGKAGGVKLVRSKEDAAAFAQQWLGKRLVTYQTDANGQPVTKILVESCTDIAKELYLGAVVDRSSRRIVFMASTEGGVDIEKIAHDTPEKILKATIDPLVGAQPFQGRDLAFQLGLEGKQVTQFAKIFTGLAKLFQDHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKGFHDPSQDDPREAHAAKFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDTNVAAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKIPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MTSA_STRSA
Sequence: MKKLGFLSLLLLAVCTLFACSNQKNASSDSSKLKVVATNSIIADITKNIAGDKIDLHSIVPVGKDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVKNANKEENKDYYAVSDGVDVIYLEGQSEKGKEDPHAWLNLENGIIYAQNIAKRLIEKDPDNKATYEKNLKAYVEKLTALDKEAKEKFNNIPEEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKSLVEKLRKTKVPSLFVESSVDDRPMKTVSKDTNIPIHAKIFTDSIADQGEEGDTYYSMMKYNLDKISEGLAK
What is the function of this protein?
Part of an ATP-driven transport system for manganese.  Also acts as an adhesin which is involved on adherence to extracellular matrix.  It is an important factor in the pathogenesis and infection.  It may contribute to the formation and accumulation of dental plaque.
What are the official names of this protein?
Manganese ABC transporter substrate-binding lipoprotein, Adhesin B, Saliva-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GLO2_SHIDS
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTLVCCAHEYTLSNMEFALSILPHDLSINDYYRKVKELRAKNQITQPVILKNERQINVFLRTEHIDLINVINEETLLQQPDERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: ATPE_PROM4
Sequence: MSLTLRVLAPDKNVFDGIAEEVILPSTTGLLGILPGHISMVTAIDTGVLRVRTNGNWDSIALMGGFAEVESDEVTVLVNAAELASEINASDAESEFEQAKTEFGQLEGQENSTQKIKAKEMLNRARARVQATKSA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: TGT_STRPF
Sequence: MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSIGGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSEGRLVVKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIRLTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.