PharMolix/UniProtQA huggingface dataset:
Protein: PUB17_ARATH
Sequence: MASAAIFSSLRRRRSPSLEAFLAPVDLSGVALVQTLASISSEVVSCFTSVRFSFQRKNARSLIRKIEIFVVLFEFLVDSNWGSTTTRTRARRRSKSSVSESTALLCLKELYLLLYRSKILVDYCAQSSKLWLLLQNPSISGYFHDLNQEISTLLDVLPVNDLGLSDDIREQIELLQRQSRKARLYIDKNDESLRESFYSFLDGFENGKIPSSVDLRMFFVEKLGIRDSKSCRSEIEFLEEQIVNHDGDLEPTGSVINGFVAITRYCRFLLFGFEEDGMEWWIENNPKKPRKGFVAQEIGDTFITVPKDFVCPISLDLMTDPVIISTGQTYDRNSIARWIEEGHCTCPKTGQMLMDSRIVPNRALKNLIVQWCTASGISYESEFTDSPNESFASALPTKAAVEANKATVSILIKYLADGSQAAQTVAAREIRLLAKTGKENRAYIAEAGAIPHLCRLLTSENAIAQENSVTAMLNLSIYEKNKSRIMEEGDCLESIVSVLVSGLTVEAQENAAATLFSLSAVHEYKKRIAIVDQCVEALALLLQNGTPRGKKDAVTALYNLSTHPDNCSRMIEGGGVSSLVGALKNEGVAEEAAGALALLVRQSLGAEAIGKEDSAVAGLMGMMRCGTPRGKENAVAALLELCRSGGAAVAEKVLRAPAIAGLLQTLLFTGTKRARRKAASLARVFQRRENAAMRSGVYGFVGNTNGNRDGGFTTDVSVPISISISVPVL
What is the function of this protein?
Functions as an E3 ubiquitin ligase.
What are the official names of this protein?
U-box domain-containing protein 17, Plant U-box protein 17, RING-type E3 ubiquitin transferase PUB17.
Protein: FTZ_DROHY
Sequence: MAATNTHYYADSMYNMYHHALPPTYYDNTSSSSSYYQSSQGWQPASYQGSSYAHYSQESYSESCYYANYHHQQQQQQHQDQPLCLPTLDAVPQYQVPTIAEPVIETSSPAPVKSRKRKAEESAADIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTIEHVKKPSKSSSAGELSPCYEQDYAVPTPSTQQTHMSPQRSTGEDVDYLDVYSPRKQAKHGDFITPPPAATTPVDGIGITISTPPQSPAEKSNEINHRIVTAANSSNEFNWSHIEETIASDCKDSKRTRQTYSRYQTLELEKEFHFNRYITRRRRMDIAHALNLSERQIKIWFQNRRMKSKKDRTLEASPDHCTTTGYASLLPPLDATAMPPQTQPQPQPHLQPAAAMPYAAYPAYLPATQQSYDYPQQSPPPPHFAQPYDAQYTPQYHQQTQQQCSYQQQQQQQELNTSNQALYHLP
What is the function of this protein?
May play a role in determining neuronal identity, may be directly involved in specifying identity of individual neurons.  Required during embryogenesis for the process of body segmentation.  Homeotic protein, required in alternating segment primordia, it specifies the correct number of segments (By similarity).
What are the official names of this protein?
Segmentation protein fushi tarazu.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_CLOPE
Sequence: MNRLQERYEKEVVPAMMEKFGYKNIMQVPKIEKVVINMGVGEAKDNPKVLESAVSDLQIIAGQKPVLTRAKKSVANFKIRENMALGCKVTLRKTNMYEFVDKLVSIALPRVRDFRGVSAKAFDGRGNYSLGIKEQLIFPEIEYDKVDKVRGMDIIFVTSANTDEEARELLRFLGMPFAQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: AN32D_HUMAN
Sequence: MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANLPKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDLFTCEVTNLNNY
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32 family member D, Phosphoprotein 32-related protein 2, Tumorigenic protein pp32r2.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
Protein: NRDR_ZYMMO
Sequence: MRCPFCSCENSQVKDSRPTEDGTAIRRRRQCEECGARFTTFERIHMRDIVVIKKDDHRQPFDRSKLIRSVSIACRKRPVSPDQIELLVNSIQQKIEASGESEITAVRLGEMTMEGLRTLDSVAYIRFASVYKDFTEARDFEDFARSVRSVIEAVKE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PRMA_BRUA2
Sequence: MAQSRLFFSADKAEAERTYNILEQAFEDDGFPIAITEIDEDRQIFEVSVYVEDDAEEVAARVDALVGPGLFDTEELPDIDWVTHSLEGLKPVRAGHFFVHGSHDRDKIEPGDIAIEIDAGLAFGTGHHGTTAGCLELIEETVETEHPTNALDLGTGSAVLAIAIARLAPIPILATDIDPIAVTVAAENAAKNGVAEHIVTATAEGFGHPIFRSYSPFDLIVANILANPLIELAPSIKEHLAPGGSIILSGILDSQHDAVLAAYQTQGLTHQKTLHREGWVAIHLT
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_BUCAI
Sequence: MNKKFKKIVTEKKLTDAERIKENSNYLRGTITDDLKNEITNGFTGDNFSLIRFHGMYQQDDRDLRIERNEQKLEPRYAMMLRCRLPGGVIKAKKWLKIDYFASKYTLYGTIRLTNRQTFQFHGILKKNLKDVHKMLHSIGLDSLATANDVNRNVLCTSNPMESLIHQEAYEWARKISNFLLPHTKAYAEIWLDQKKIVTTEKEPILGKTYLPRKFKTTVVIPPYNDVDLYANDMNFVAITKNEKIIGFNILIGGGLSFIHGNKNTWPFLATEIGYISVENTLSIAKAIVTTQRDWGNRTDRANAKTRYTINNFGLNEFKKEIEKRANVNLKPVREYSFISRGDRFGWIKDINNNWSLTLFIQNGRIYDDNDKLFKSGLLKIANIHDGNFRITSNQNIIISEVSEKNKNKIEKIALSSGLINKSTNLRKNSMACVSFPTCPLAMAEAERMLSFFITQLENIMLKYGVEDEVIILRVSGCPNGCGRSLLAEIGLIGKSIGRYNLYIGGNRIGNRIPKIYKENITEQEILIHLKYLIKTWSNERKNKEDFGDFIVRKEFVKEVINPVYDFWS
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: PSAJ_NOSP7
Sequence: MADKGDQSSYLIKFISTAPVAATIWLTITAGILIEFNRFFPDLLFHPLP
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MENE_STAAE
Sequence: MDFWLYKQAQQNGHHIAITDGQESYTYQNLYCEASLLAKRLKAYQQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMKSIDVQLIFCTLPLELRGFQIVSLDDIEFAGRDITTNSLLDNTMGIQYETSNETVVPKESPSNILNTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYHISGLSVLLRAVIEGFTVRIVDKFNAEQILTMIKNERITHISLVPQTLNWLMQQGLHEPYNLQKILLGGAKLSATMIETALQYNLPIYNSFGMTETCSQFLTATPEMLHARPDTVGMPSANVDVKIKNPNKEGHGELMIKGANVMNVYLYPTDLTGTFENGYFNTGDIAEIDHEGYVMIYDRRKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESDISKAQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKLQRNKLYRG
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: SYL_POLNA
Sequence: MQDKYNHLDVERSAQTHWNAADAYRVTEDASRKKYYACSMLPYPSGKLHMGHVRNYTINDMLSRYLRMKGYNVLMPMGWDAFGLPAENAALKNGVPPAQWTYDNIAYMKKQMQAMGLAVDWSREIATCDPSYYKWNQWLFLKMLEKGIAYRKTQVVNWDPVDQTVLANEQVIDGKGWRTGATVEKREIPGYYLKITDYAEELLGSVQHKLPGWPERVKLMQENWIGKSEGVRFAFLHDIKDASGALIGDGQMYVFTTRADTIMGVTFCAVAPEHPLAVHAAASNPALAAFVEECKSGGTTEAELATQEKKGQPTGLFVTHPLTGDKVEVWVGNYVLMSYGDGAVMGVPAHDERDFEFAKKYGLPIKQVTDVKGQAYSLDAWADWYGDKQHGIAINSGKYDGLAFKAAVDAIAADLAALGLGEKKTTWRLRDWGVSRQRYWGTPIPIIHCDEHGAVPVPEKDLPVVLPMDCIPDGSGNPLHKHEGFHAGVVCPVCGKPARRETDTMDTFVDSSWYFMRYCDPKNSEAMVAGGADYWMPMDQYIGGIEHAILHLLYARFWTKVMRDLGLVKVDEPFTKLLTQGMVLNHIYSRRTDKGGKEYFWPHDVEHVLDDTGKIAGARLKNAVGDLPVGTAIDYEGVGTMSKSKNNGVDPQDIIEKYGADTARLYTMFTAPPEATLEWNDAGVEGSYRFLRRVWNFGVKLNAMNSGANGADAACAKGLFDKETKALRLEVHTLLKQVDYDYQRMQYNTVVSGGMKLLNALEDFKGEISAASLAALREGFSVLLRCLYPAAPHLTHALWSELGYAAEAGDLLDTPWPEVDASALQQDEIELMLQINGKLRGSVTVPAGADKAVIEAAALASEAFVKQAAGAPAKKVIVVPGRLVNIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_DESVM
Sequence: MANHKSAIKRHKQSQKRAARNRAAKTRIKNVVKAVRAAVLQKDKDTAAQALTAAMSVLDKAAGKGVIHWKKAARKISRLTKAVGSVE
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PBSS_PENBI
Sequence: MDFLSGAFHYSDSVNPSKYSPRPSDYFGTLPFRTSRFEREAADVTADYLRKWQKAVKADNPERKDLVFHGSTTTLGHFVSWAYPECIPDRVDLCTQICDFGFYWDDVTDSVNVQENAEITQDLALALLSELTLGQRLEPKLEINKIVVQMLWGVLDKDRKSGLEMIKFWKGHLDGQAESAHNNMSFEEYTKHRLSEVGARWAVEVGCWSLGINLSREKKDSVAHFVNKGLLAAALMNDYYSFNKEFDEHQRAGSMDRLQNGLGILMREYGYTETEARSILREEIRKGERAIMDGYIAWRESADSSSESHELNRYIVMIILMIGGITFWSSHASRYHRDDLITTAGDRAMIVGKFQCSMRLLDGYPPPNRWKSATSSNDISGRKRKSWSDSNGVDTHGACYTNGSSNRAKRNGTEAGHKANGHDSMDIYTAPFLKAPSEVCEAPYEYINSLQGKNMRNKFMDALNHWLCVPAPSMQIIKNIVQMLHNSSLMLDDIEDESPLRRGQPVAHTFYGISQTINSANFVYVKSVKETSRLKNPICMEIFTDELSNLHTGQSLDLYWRYHGRCPSINEYIMMVDNKTGGLFRLMLRLMEAESPAASSASLVKLLTLTGRYYQIRDDYLNLTSVEYTSKKGFCEDLDEGKFSLPLLHLLNHTRHPDRITAPLFNRASGARSLAREVKVHIIQAMDEAGTFEYAQGVLKYLHEEIMRTLDEVEADLGRNTEARILLLGLGL
What is the function of this protein?
Bifunctional sesterterpene synthase that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylfarnesyl diphosphate (GFPP) and further converting GFPP into sesterbrasiliatriene.
What are the official names of this protein?
Sesterbrasiliatriene synthase PbSS, Bifunctional sesterterpene synthase PbSS, SS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FPP/GGPP synthase family.
Protein: G3P_LENED
Sequence: MAVKVGINGFGRIGRIVLRNALLNPEVNVVAVNDPFIALEYMVYMFKYDSVHGRFKGTVETKGGKLIVDGKEISVFGEKDAGAIPWSSVGAEYIVESTGVFTTIEKASAHLKGGAKKVIISAPSADAPMYVCGVNLDSYDSQHAVISNASCTTNCLAPLAKVIHDKFGIVEALMTTVHATTATQKTVDGPSNKDWRGGRSVNGNIIPSSTGAAKAVGKVIPSLNGKLTGLAFRVPTLDVSVVDLVCRTEKSATYDEIKAAVKEASKGPLKGILGYTEDHVVSTDFIGDNHSSIFDATAGIQLNKNFVKLIAWYDNEWGYSGRVVDLLVFAAKKDGAL
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_PROM0
Sequence: MVKIGVLLMNLGGPERITDVGPFLYNLFSDPEIIRTPFPVFQKPLAWLISTLRSTTSQQAYLSIGGGSPIRRITEQQARELQSKLREKGFNATTYIAMRYWHPFTESAIADMKADGIDQVVVIPLYPHFSISTSGSSFRELKKLRDSDDEFKKVPMRCVRSWFSQSGYLKSMVELISEQISLCESPSKAHIFFTAHGVPKSYVEEAGDPYKQQIEDCSLLIINELEKCLGYSNPHTLSYQSRVGPVEWLKPYTEEVLADLGRSNVNDLVVVPISFVGEHIETLQEIDIEYKEIAEKAGIKNFRRVKALNTHPTFIEGLSDLVISCLEGPLVNIEEASQLPEKVKLYPQEKWQWGWNNSSEVWNGRVAMIIFLVLFIELISGSGPLHKLGIL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_SALPB
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPAFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKSDTSPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTEFYQRQGRPVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: QRT2_ARATH
Sequence: MYEKIIILSVFLLTFLPSCFSSYPFNHRDDLFMSSNVYYETNRQHQHGHNTRNSHLKNRHGYAPRSSPRSFNVNTFGAKANGNDDSKAFMKAWEAACSSTGIVYIVAPKNRDYMLKAVTFSGPCKSSLIIFKIYGRIEAWENPSDYKERRHWIVFENVNNLRVEGGGRIDGNGHIWWPKSCKINPQLPCLGAPTAVTFVECNNLRVSNIRLENAQQMHLTFQDCKNVKALNLMVTSPADSPNTDGIHVSGTQNILIQDSIVRTGDDCISIVSGSENVRATGITCGPGHGISIGSLGEDNSEAYVSNVVVNKATLIGTTNGVRIKTWQGGHGMAKNIIFQDIIMKNVTNPIIINQDYCDRVEACPEQKSAVQVSNVLYKNIQGTSSRPIAVKFVCSKNIPCRGISMQNVKLVDQTQQDVSKASCSNVKLDTRGNVSPLCT
What is the function of this protein?
Polygalacturonase required for cell type-specific pectin degradation to separate microspores.  Involved in anther dehiscence and floral organ abscission.
What are the official names of this protein?
Polygalacturonase QRT2, AtQRT2, PG QRT2, Pectinase QRT2, Protein QUARTET 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ADD_KLEP3
Sequence: MIDSSLPLTDIHRHLDGNIRAQTILDLGREFNIALPASTLDTLRPHVQVTSLEPDLVSFLAKLDWGVKVLASLEACRRVAYENVEDAARNGLHYVELRFSPRYMAMTHQLPVDGVVEAVIAGVREGSRDFQVDARLIGILSRTFGEAACQEELAALLAHREGITALDLAGDELGFPGALFLNHFNQARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDPALMDYLAEHQIGIESCLTSNVQTSTVASLAQHPLKQFLEHGVLASLNTDDPAVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLTQAFLSEQEKAALIQRVAKG
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: COAE_STAA3
Sequence: MPKVIGLTGGIASGKSTVSELLSVFGFKVVDADKAAREAVKKGSKGLAQVREVFGDEAIDENGEMNRRYMGDLVFNHPEKRLELNAIIHPIVRDIMEEEKQEYLKQGYNVIMDIPLLFENELENTVDEVWVVYTSESIQMDRLMQRNNLSLEDAKARVYSQISIDKKSRMADHVIDNLGDKLELKQNLERLLEEEGYIEKPNYGEED
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRMS1_BOVIN
Sequence: MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQTESEEESSEMDEEDCERRRSECVSEMMDLEKQFSELKEKLFRERLSQLRVRLEEVGAERAPEYTEPLGGLQRSLKIRIQVAGIYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTLQGELQERIQRLEEDRQSLDISSEWWDDKLHARGSSRTWDSLPPNKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARAAVSPQKRKSDGP
What is the function of this protein?
Transcriptional repressor.  Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'.  Promotes HDAC1 binding to promoter regions.  Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B.  Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis (By similarity).
What are the official names of this protein?
Breast cancer metastasis-suppressor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the BRMS1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Protein: RS7_RAT
Sequence: MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for rRNA maturation.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S7, S8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.
Protein: MNMA_CYTH3
Sequence: MSKKGRVLVAMSGGIDSSVAAVMLHEQGYEVIGMTMKTWDYANLGGSKKETGCCSLDSINDARNIAVSLGFPHYIVDIREEFGDYVINHFNKEYLDGRTPNPCVLCNTHIKWDSLLRRADKMDCDFIATGHYAQVRSENNRFVISKGLDENKDQSYALWGISQQSLSRTMFPLGHLHKTDIRAMAAERGFMDLVNKSESYEICFVPDNDYRGFLKRRNPGLEEEVRGGEFVMEDGTVVGKHEGYPFYTIGQRKGLGITLGYPVFVTEIQKENNRVVLGREEGLNRNGMWVDQLIMSKYENLKGIQKQSITKVRYNDDGTSSTIEQVGDEMRVLFHEHVKAIAPGQAAVFYEGNDVIGGGWIKSSFKQD
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBJ_PHAAO
Sequence: MTDTTGRIPLWLIGTLTGILVIGLIGIFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LOLA_HAES1
Sequence: MKKYLNLTALLLVGISNVTWANAVNELQNRLNKIDVLSADYTQQVTDAQGKKIQQGSGKIQLKRPNLFRMDNETPQESQIIADGKTLWFYDPFVEQVTANWVEDTLSDTPFVLLTSNNPSHWQQYIVEQKSDTFIIKPKSKKSTIKQFNIRIEKDGVLKNFSTIENDGQSNLYILRKITNPALNDAIFTFTLPKGVEFDDQRKK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DHMA_MYCPA
Sequence: MHVLRTPDSRFENLEDYPFVAHYLDVTARDTRPLRMHYLDEGPIDGPPIVLLHGEPTWSYLYRTMITPLTDAGNRVLAPDLIGFGRSDKPSRIEDYSYQRHVDWVVSWFEHLNLSDVTLFVQDWGSLIGLRIAAEQPDRVGRLVVANGFLPTAQRRTPPAFYAWRAFARYSPVLPAGRIVSVGTVRRVSSKVRAGYDAPFPDKTYQAGARAFPQLVPTSPADPAIPANRKAWEALGRWEKPFLAIFGARDPILGHADSPLIKHIPGAAGQPHARINASHFIQEDRGPELAERILSWQQALL
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
Protein: TYW1B_HUMAN
Sequence: MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEVTSKNVCVFLVATYTDGLPTESAEWFCKWLEEASIDFRFGKTYLKGMRDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIEANFRAWKTKFISQLQALQKGERKKSCGGHCKKGKCESHQHGSEEREEGSQEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPSLACANKCVFCWWHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLMLVKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCLLIAHRKFKIGGEWWTWIDYNRFQELIQEYEDSGGSKTFSAKDYMARTPHWALFGANERSFDPKDTRHQRKNKSKAISGC
What is the function of this protein?
Probable component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity).
What are the official names of this protein?
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B, Radical S-adenosyl methionine and flavodoxin domain-containing protein 2, tRNA wybutosine-synthesizing protein 1 homolog B.
What is the protein family that this protein belongs to?
Belongs to the TYW1 family.
Protein: URED_METFK
Sequence: MDDVNTKTAAWADKRWQALLALDFSSRAGRTTLIGKRHQGPLVVQKMLYPEGDEVCHGIIIHPPGGVAGGDQLQLQATLEASARALLTTPGAGKWYKANQLSASQAVRFHLAANSCLEWLPQENILFDGSNVHFSSEIDLAEGAVFCGWDILCFGRQARGERWSEGELRQVMQVRREGRLIWNERLFAQPDSLVMRSGIGLKGMPVNGSLVVAAGTVPVEIIEACRAIEARGDAHYGVTALPEILSARYIGASSEAAKEYFERLWQVLRPWYAARPATRPRIWNT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_SHEPC
Sequence: MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKGLFVKELEVAILEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNIYKTISELPLGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLSGRIASFISAEQSLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEGGCQVPIGAFAEINGDEMTLRGLVGNPDGSEIIEGIITGPKTEATQLGVALAEELLSKGAKSILDAVYAKA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: VATE_METMJ
Sequence: MGLEAVVNEIREKGRKEVETIRAETRTDVEEILVDAQTRAAGIKASAQEEADRAVTHIINQEASAANLVVKRQVLNAQKTLLDQVYSASLAAVGDLPAEFQEKALTALLKRAVKEIKKGVVHANERDSPVVEEILSQLKMFSGYTMGAPVDIPGGIIVESNDGELQIDYSYRTFLDEIWESGLKDASDILFT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.