PharMolix/UniProtQA huggingface dataset:
Protein: TIM50_KLULA
Sequence: MLSIARVSLLRNARMVPVHAMQMRPVVVRRSLHNGSLLLQKKNEKNEAPKSILDDDMLARAGVEVEGNEAGSKDKSGRAGEAGESAEQDDSTGDKGSGKKKRSRKSSTDIKRERYANWFYILSLLGLASGALSMARDWDSDESEELKKEIPNGYTPALMYKRMKRRWESIFTFFQEPPFPDLLPPPPPPPYQRPLTLVLSLEDLLVHSEWTQQSGWRTAKRPGVDYFLGYLSQYYEIVLFSSNYMMYAEKIAEKLDPIHAFITYNLFKEHCLYKDGVHIKDLSKLNRDLGKVLIIDTDENSFKLQPENAIYLEPWDGKADDRLLRLIPFLEYLATQQVSDVRPILKSFPDNKNIPEAFEKRVQVLKEKFERDERVKNDKNLFLKLLGIGLIGTKPKFPLDLIREEGEKNYVRFMKLVEEEKEKIKLQQQAMGQQTFTLKDYVEGNIPTPEEQLKLQMEKQQEIEAQFEEQKKLKAQQGSK
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM50.
What is the protein family that this protein belongs to?
Belongs to the TIM50 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: Y3407_METJA
Sequence: METTIMVVAMDRLTYYKLTSRYLYYFCLDRLLSCHRLDLDRDRKINWRHPKYWNYNNIPKGEKPYLRHIDLWDYRGNFKDWIIENLRSIYCSPYYFESPRYELEYPAIDYNYWDWVIDIDFKGNFKKSKEIAKEVREIFKDYGVKDIHIKFSGSKGFHIWINARYLPNEILNKGYVEGSTILTNFLNFKLRKLLDFVGKEGDTGIDLSIYKENMTVTAPFSLYYADIEGKTPISIPFPINKVEKFKPIYLQNVKPYFIRKLTKYYENFGEIRGDLTDFVDDALRYYQATKKVNNDIKIDLEINTNKKAKPKVEHSKREYIKTTIGDKEVVLNKVKLESYLNELINSNWEDGKMRGCYYLTSLCKLLGYGRDKTIKLLNRWASKYGNKYIKHIDYEVRYLYDRNGKVCSIKWLKENIPEAKTQIEIYKKYYELDKNNYLVKK
What are the official names of this protein?
Uncharacterized protein MJECS07.
Protein: SYS_BACAN
Sequence: MLDIKFLRTNFEEVKAKLQHRGEDLTDFGRFEELDTRRRELLVQTEELKSKRNEVSQQISVLKREKKDAEALILEMREVGEKVKDLDNELRTVEEDLERLMLSIPNIPHESAPVGETEDDNVVARTWGEVKEFAFEPKPHWDLATDLGILDFERAGKVTGSRFVFYKGAGARLERALISFMLDLHTDEHGYEEVLPPYMVNRASMTGTGQLPKFEEDAFRIESEDYFLIPTAEVPVTNMHRDEILNKEQLPIRYAAFSSCFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYEELEKLTNDAERVLQLLELPYRVMSMCTGDLGFTAAKKYDIEVWIPSYGTYREISSCSNFEAFQARRANIRFRREPNGKPEHVHTLNGSGLAIGRTVAAILENYQQEDGTIIIPEVLRPYMGGKTVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_ACIAD
Sequence: MNILIANDDGVFAPGIQALAHALKPLGRVVIVAPESERSGYSSALTLDRPLRPIQISEDVWAVNGTPADCVYLSMNGLFDFEFDLVVSGINSGANLGDDVLYSGTVGAAFEGRLMKQPAIAVSLAGSNVRSYEHAHDYAVAAKWVHDFIQKGLPNLPPRHILNINIPDVAALKGERVTYQGLRAQSKPITSHVDPRGRQVYWIGLAGEAVTDPKKTSSHIQSDFFAVANGYVSITPIQMDATNYDILEDLQTYIG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_SULSY
Sequence: MHQLIREIEQKYLPQDIPEFKVGDTVRLHLKVKEGEKERTQIFEGLVIRVRGSGTGKTFTVRKVSYGVGMERIFPIACPSIQKIEVVKRGKVRRAKLYYIRNLKGKAAKIKELKEWEIKKRQAESQASKENNG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: INSI2_XENTR
Sequence: MGETDNAPRGPPSFLPHKMNLLLRGLLLFLIGVFLALVLNLLQVQRNVTLFPPDVLSSLFSSAWWVPLCCGTAAAAIGLLYPCIDRHLGEPHKFKREWSSVMRCVAVFVGINHASAKVDFANNTQLSLTLAALSIGLWWTFDRSRSGLGLGIGISFFATVVSQLLVYNGVYEYTAPDFLYVRSWLPCIFFAGGITMGNIGRQLEMYERLALVEKSHRD
What is the function of this protein?
Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of scap and degradation of hmgcr.  Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs).  Binds oxysterol, including 22-hydroxycholesterol, 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol, regulating interaction with scap and retention of the SCAP-SREBP complex in the endoplasmic reticulum.  In presence of oxysterol, interacts with scap, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing scap from escorting SREBPs to the Golgi.  Sterol deprivation reduce oxysterol-binding, disrupting the interaction between insig2 and scap, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBPs.  Also regulates cholesterol synthesis by regulating degradation of hmgcr.
What are the official names of this protein?
Insulin-induced gene 2 protein, INSIG-2.
What is the protein family that this protein belongs to?
Belongs to the INSIG family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DTD_CLOPS
Sequence: MRVVVQRVNKSSVKVDNEIVGSINKGFNVLVGIGKEDTIEDLKYMKDKVLNLRVFEDEEDKMNLSLKDVCGELLLISQFTLYGDCRKGRRPNFMNALGGDEAKKLFDEFVSMCREEGIKVETGVFGAHMVVDIENDGPVTLILDSKKNF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_CUPMC
Sequence: MATLTPRQQQIFDLIRDTIRNTGFPPTRAEIAAEFGFSSPNSAEEHLRALARKGVIELTPGASRGIRLKVTRSDSERPDQFSLPMPGVLQLTLPLVGRVAAGSPILAAEHIDRQYQVDASVFDERPDYLLRVRGLSMRDAGILDGDLLAVKKASEAANGKVVVARLGDDVTVKRLKKRGDTIELIAENPDFQNIVLHAGRDEFSLEGIAVGLIRSSGF
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SEC13_ASPFU
Sequence: MTRGTNLVGPFLQHDAGLDYYGRRLATCSSDKTIKIFEIEGETHRLIETLKGHEGAVWCVAWAHPKFGTILASSSYDGKVLIWREQHQNATSPVAGSTWTKVFDFSLHTASVNMVSWAPHESGCLLACASSDGHVSVLEFRDNSWTHQIFHAHGMGVNSISWAPAASPGSLISSNPGPGQQRRFVTGGSDNLLKIWDYNPESKTYNLSQTLEGHSDWVRDVAWSPSILSKSYIASASQDKTVRIWTSDASNPGQWTSQQLEFDTVLWRVSWSPSGNILAVSGGDNKVSLWKENLKGQWEKVKDIEE
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein sec13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: NGFV_BUNMU
Sequence: MSMLCYTLIIAFLIGIWAAPKSEDNVPLGSPAKSDFSDTNCAQTHEGLKTSRNTDQHHPTPKKSEDQELGSAANIIVDPKLFQKRRFQSPRVLFSTQPPPLSRDEQSVKFLDTEDTLNRNIWANNENHPVHNQGEHSVCDSISVWVTNKTKATDIKGNTVTVMVDVNLNNEVYKQYFFETKCRNPNPVPSGCRGIDSRHWNSYCTTTDTFVKALTMEGNRASWRFIRIDTACVCVISRKTENF
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor, v-NGF, vNGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: NCCB_ALCXX
Sequence: MMTKNERRQPSWPMIAGVAAAAALVGFGAARGLGSPSGAEVSKLAAAPEKAAASAPAAEPAEVRIPGEYLAAANIAVEPVSAGGVGSVLLAPASVAAVPGSEAVIASRAAGAVLRIQRKLGDAVRAGDVLALVDSPEAAAMAAERKVAQARADLARKTYERESSLFQQGVTPRQEMESARIALDVAQAEVQRAATVAQAAKVSSDGRSVAVVSPIAGRITAQSVTLGAYVAPQAELFRVAGSGAVQVEAYVTAADTSRIAAGSDATIVLANGAPLAGRVQAVTPTVSGSARAATVVVTPVDANSGLIVGEGVQVRLHTKAADANAMSVPEDAVQNLDGRDVVFVRTQQGFRPKSVLVGSRSGGVAQILSGVKPGEQVATRNAFLIKAEMNKAGGDDE
What is the function of this protein?
Component of the NCC cation efflux system that confers resistance to nickel, cobalt and cadmium.
What are the official names of this protein?
Nickel-cobalt-cadmium resistance protein NccB.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PRXV_COROI
Sequence: MGIPADNLQSRAKASFDTRVSAAELALARGVVPSLANGEELLYRNPDPENGDPSFIVSFTKGLPHDDNGAIIDPDDFLAFVRAINSGDEKEIADLTLGPARDPDTGLPIWRSDLANSLELEVRGWENSSAGLTFDLEGPDAQSIAMPPAPVLTSPELIAEIAELYLMALGREIEFSEFDSPKNAEYIQFAIDQLNGLEWFNTPAMLGDPPAEIRRRRGEVTVGNLFRGILPGSEVGPYLSQYIIVGSKQIGSATGGNKTLVSPNAADEFDGEIAYGSITISQRVRIATPGRDFMTDLKVFLDVQDAADFRGFESYEPGARLIRTIRDLATWVHFDALYEAYLNACLILLANRVPFDPNIPFQQEDKLDNQDVFVNFGDAHVLSLVTEVATRALKAVRYQKFNIHRRLRPEATGGLISVNKIAAEKGESVFPEVDLAVEELEDILEKAEISNRKQNIADGDPDPDPSFLLPQAFAEGSPFHPSYGSGHAVVAGACVTILKAFFDSNFQIDQVFEVDKDEDKLVKSSFKGTLTVAGELNKLADNIAIGRNMAGVHYFSDQFESILLGEQVAIGILEEQSLTYGENFFFNLPKFDGTTIQI
What is the function of this protein?
Catalyzes the halogenation of organic substrates in the presence of hydrogen peroxide.
What are the official names of this protein?
Vanadium-dependent bromoperoxidase, Vanadium haloperoxidase.
What is the protein family that this protein belongs to?
Belongs to the vanadium-dependent haloperoxidase family.
Protein: Y4248_SHEON
Sequence: MAIKDWPEGEGPRDKLLLKGASHLSDAELLAVLLRNGLSGLNAVDLARSLIQEFGGLRSLLCAPKHQVCRLPGVGPVKYAQLQAAAELARRVAQENLQRGQVLTNPDLTRDYLMRQLADRSYEVFAILLLDSQHRVIQFVELFRGTIDSASVYPREVVSLVLEKKAAAVIVCHNHPSGIAEPSQADRRITERLKNALATIDVSLLDHMVVGDREIVSFAERGWIN
What are the official names of this protein?
UPF0758 protein SO_4248.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: HRPN_ERWAM
Sequence: MSLNTSGLGASTMQISIGGAGGNNGLLGTSRQNAGLGGNSALGLGGGNQNDTVNQLAGLLTGMMMMMSMMGGGGLMGGGLGGGLGNGLGGSGGLGEGLSNALNDMLGGSLNTLGSKGGNNTTSTTNSPLDQALGINSTSQNDDSTSGTDSTSDSSDPMQQLLKMFSEIMQSLFGDGQDGTQGSSSGGKQPTEGEQNAYKKGVTDALSGLMGNGLSQLLGNGGLGGGQGGNAGTGLDGSSLGGKGLQNLSGPVDYQQLGNAVGTGIGMKAGIQALNDIGTHSDSSTRSFVNKGDRAMAKEIGQFMDQYPEVFGKPQYQKGPGQEVKTDDKSWAKALSKPDDDGMTPASMEQFNKAKGMIKSAMAGDTGNGNLQARGAGGSSLGIDAMMAGDAINNMALGKLGAA
What is the function of this protein?
Elicits the hypersensitive response (HR) in the plant upon infection.  Harpin elicits HR in non-hosts and is also required for pathogenicity in host plants.
What are the official names of this protein?
Harpin HrpN, Harpin-Ea.
What is the protein family that this protein belongs to?
Belongs to the harpin HrpN family.
What are the subcellular locations of this protein?
Secreted. Note=Via the HRP secretion pathway.
Protein: IF2_BORPA
Sequence: MSSNTVAQFATELKMPANVLLEQLRAAGVDLKSVDDAVTDSDKAKLLESLRRAHGATEGKKITLTRRQTSEIRQADATGRSRTIQVEVRKKRVFVKRDPAEPVRAEPAVETAAKPVEPPVAEAPAEPVAAPAAEPQPEQPAQAEAQPEPTPAAQAEPEPQPEPQPEAAPAQAVAEPVEPAKNVSVTETEAEQARPEPVVHAQTELTSQTPAPVAQPSAPAESPKSAKAEPAAAPKTTAKPGEIRRAAAPAAPDRAREEARRAAEAEAAALREMLSRPRKVLRAPEPEPQAGALSGTLHKPAGKPATTAAPKKDAKPGAPGAKKTIKTAEVSSTWSDDSARKKPADNKPAVTTRDGWRAGGKGGRGGRNSRNQHQDRRHEQVQQEFIAREIHVPETISVADLAHKMSVKAAEVIKQLMKLGQMVTINQVLDQETAMIVVQEFGHTAIAAKLDDPEAFLDETAAVTEAEAEPRAPVVTVMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETGRGVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTREAIHHAKAGGVPLVVAVNKIDKPEANPERVKQELVAEEVVPEEYGGDVPFVPVSAKTGAGIDDLLENVLLQAEILELKAPIEVPAKGLVIEARLDKGRGPVATILVQSGTLKRGDVVLAGASFGRVRAMLDENGKQIQTAGPSIPVEIQGLTEVPAAGDELMVLSDERKAREIALFRQGKFRDVKLARQQAAKLESMFDNLGEGTQTLALIVKTDVQGSQEALVSSLTKLSTDEVRVQVVHAAVGGISESDVNLAIASNAVVIGFNVRAEQSAKKLAETNGIDLRYYNIIYDAVDEVKAAMSGMLAPEKREEVIGLVEVREVYTISRIGTVAGCMVLDGVVRRDSQVRLLRNNVVQWTGHLDSLRRFKDDVKEVKSGFDCGLTLRGNNDLQLGDQLEVFEIKEIARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLR3_PLAVT
Sequence: MRASTILFVLGAAILAVIGVTTALDSGEIDKSTQENHRLLRSGSMEQEPDEERKFIKVPSFMNKAAREAKKAKKKAEIANLVWLKLQKYSDSYALNYVDDMVKSGRSADDEIKFLKKHMKVSNNLQRVIEGHFRSHAELGRVLAKPKYK
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 3.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm.
Protein: RL27_RHORT
Sequence: MAHKKAGGSSRNGRDSEGRRLGVKKFGGEIVVSGNIILRQRGTKYHPGANVGLGKDHTIFATTPGNVKFHKGFRGRMFVSVVAEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: 25KD_SARPE
Sequence: MMDWNNKNVVYVGGFSGFGYQVCQMMMKKPMKHLIVCSRMENVEMLKKLQAINTSVKVMFVQMNIADYASIVKGVKQVIGHVGHVDVLINGVGGLADKDVETTVAVNLTGLINTTLMFMPYMDKTQSGHGGMVVSISSVYGLEPGPAFSVYSAAKHGGIGFTRSMADEHLYHKTGVAFMCICPAMTSTELMMNKRDMNWMKWVPHSEEMWKMVMDAKMQTPEECAVNMMTAMEQAKNGAIYICSTSGMKEITPTVYMH
What are the official names of this protein?
Development-specific 25 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ISPD_CHLT3
Sequence: MQAIAIIAASGVGKRMKLPSGKTKQYLKLGVYPVIYYALSAFQQASSVEAIFVATLPSHIAYLQKMARRYGFHKVKFVIEGGKERQDSIFNCVEKIREVYGDDGALQDKVILIHDGVRPFIQPNEIDEIAELSKSFGACVPATKPKDTIKYIDGDDNRFFGETLDRSKLLQVQTPQGFRADLIMSAHQKAQSDSFYATDDAALTEAYFPEQKIKIFEMGYHNIKITTPEDMDLGKAILKRLRQSK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: METK_CAMSI
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDQDSKVACETCTKTNMVMVFGEITTKAAVDYEKIVRDTCRTIGFVSDDVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKRPEEIGAGDQGHMFGYATDETSELMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNEKGATVPIRVHTLLISTQHDETVTNDEIAADLKEHVIKPVIPDKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVANGLARRCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKESFDFRPGMIAINLDLKRGGNSRFLKTAAYGHFGRDDPDFTWESGEAPQVGQTSS
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_PROM3
Sequence: MTLPVWVAAAARAATEALLGRPFSAFQLLELPDRDEPFAVSVTSAAVLAGGEQALSISHCDPGPGLDLTRGLEIWVCVQWQELVVGVDDELNVHSEAWLNLVAGKGVGTLGSGGEACVSRFARELLSRNLYPLVPSGRGLRLEVVLPRGRDLAARTSNAAFGVVDGLALIGTQADVQVSASPDQLQQTIEQLRRQSAASDFCGAMTLVIGENGLDLARQLGLAVQPLLKIGNWLGPVIVAAAEAGVEQLLLLGYHGKLVKLAGGIFHTHHHLADGRLEVLAAMAVREGLPLDLIRQLGQADSMEAALKMLEAQDPELVRKLWYRLAATVEHRSAAYLARYGSWSIAIGAALFDRQRRLRWAGPQGSQQLAVLGVTPEDSPISLSLP
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: LOLD_METFK
Sequence: MSDSTILQCVDLQKTYTGLDVAVLNGISLQVDAGEQIAIVGTSGSGKSTLLHLLGGLDEPSAGSVQVMGKSLAALSEAERGTLRNRALGFVYQFHHLLPEFTALENVALPLMIRRLSRDEALGRAKDVLMQVGLGHRLEHMPGELSGGERQRAAVARALVTNPRCVLADEPTGNLDRHTAQGVFDLLLALNRDQGVALVVVTHDLELAARMQRQYRLQDGRLHTI
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YCIH_SALTI
Sequence: MSDSNSRLVYSTQTGRIEEPKTAPVRPKGDGIVRIQRQTSGRKGKGVCLITGIEMNDAELTKLAAELKKKCGCGGAVKEGIIEIQGDKRDLIKSLLEAKGMKVKLAGG
What are the official names of this protein?
Uncharacterized protein YciH.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: NA291_NEMVE
Sequence: MASFKIVIVCLALLVAVASARRRDMMSDDELDYHFSKRGIPCACDSDGPDIRSASLSGIVWMGSCPSGWKKCKSYYSIVADCCNQ
What is the function of this protein?
Binds to site 3 of voltage-gated sodium channels and inhibits the inactivation process (PubMed:18538344).  Is highly active on DmNav1/TipE (drosophila) and is only extremely weakly active on rat Nav1. 4-beta-1/SCN4A-SCN1B, and on human Nav1. 5-beta-1/SCN5A-beta-1 (PubMed:18538344).  This reveals high specificity for arthropod over mammalian channels (PubMed:18538344).  In vivo, when released into the medium, this recombinant toxin induces impaired swimming, paralysis and death of the crustacean A. nauplii within several hours (PubMed:22048953).  Also causes paralysis of cherry shrimps immediately after injection at very low doses (PubMed:29424690).  Its effect on zebrafish (D. rerio) larvae is also rapid, since it induces tail twitching accompanied by impaired swimming after 20 minutes and complete paralysis within 45 minutes (PubMed:22048953).  It has also been observed to cause death of zebrafish larvae within 1 hour (PubMed:31134275).
What are the official names of this protein?
Putative N.vectensis toxin 1 9, Nv1, Neurotoxin Nv1-3391.7.1, Putative delta-edwarditoxin-Nvc1a, Delta-EWTX-Nvc1a.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NNRD_NEUCR
Sequence: MSSESSTGPEMSATTKQMLARVRQMVPPMLEKFHKGQLGRVAVIGGSEDYTGAPYFSAMASARLGADLSHVICTPNAAQVIKTYSPNLMVHPLMRSSPPALSSSDSGSSPSRTKSAPDTDPSQIAAQIIPMLDRLHVLVIGPGLGRDPLMQETCAKVITAAREKGIPMVLDADALLLVTKDPSLIKGYDNAVLTPNVVEFGRLTKALGVDEEVEKAEETAGETAKVEALAKALGGVMVVQKGAKDYLSDGKVTLTVDLKGGLKRSGGQGDTLTGSIATFLGWRRAYLEDLWDHGHKLNKEELIGLAVFGGSAITRECSRLAFAKKGRSLQASDLTDEVHTAFLNLFGEVDAKL
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_CHLPM
Sequence: MKQEKTVSATLVNNPALTGRGTCCDDDECLNDPAQLPAEIMESMSESVYTLLEGVGEDPEREGLLKTPERVARSLAFLTRGYRQDPEEMLKKAVFTESYDEMVLVKDIDIFSMCEHHMLPFFGKAHVAYIPDGKIVGLSKLARVVEVFARRLQVQERLTQQIRDAIQDVLHPKGVGVVIEAKHMCMVMRGVEKLNSVTTTSAMSGEFISSESTRGEFLRLIRP
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RPOE_MACCJ
Sequence: MKISEYTKEMMDENSFIDLAYMALSEKGKEVNLYELIDEFKAIGNYSDEEVETRVVQFYTDLNTDGRFLSTGEYMWGLRDWYSVDDIEEKIAPTVQKFDILDEEDEDSPKIALLGEDEVEDELDLLPSDGDEENVDTEDEEVEDELDEAGLVVEPDEEFEDEEDEFDDEEEEE
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.