PharMolix/UniProtQA huggingface dataset:
Protein: SPZ2_DROME
Sequence: MKAGRAFGCLFWALLYCVLYLDLVSGNSADDELMDFDFADSNDAAMEDWQLDDLEEAKKAEQAEKKLESNMLDFSVDLDEPEPEKQLPPFDWRERVLRNALAKALADEGLRQKFAEVLPILRMLSSQQRLALSALISAQMNAKKGHELKFEQVRMMFGNEKKLLLPIVFDIANLIKSSTRKYINLGSDLASSALYHTPINRREDDLTPEESQQDDQLGTIAVEVEPKKVSTEEVQLESLEDFFDEMGSEVLDPQMINEALTGDLHDNKTKTFKPENHGQRVRRSANEFVHKLTRSVPASVTEQQLLGGIAGRTIKLNTTAFQQPSSQEEEKMASSNGGQSYSEVEDLAFAGLNGTEIPLSADERLDLQRNSAEETEEPLPSPEELIAGPRYRLGKRPLPGQKSGSPIKRKRVTSSLRGRPKTAASSHKPVVTPPNKKCERFTSNMCIRTDDYPLEQIMGSIRRHKNAMSALLAEFYDKPNNNLEFSDDFDDFSLSKKRREDEGSAGGMCQSVVRYARPQKAKSASGEWKYIVNTGQHTQTLRLEKCSNPVESCSYLAQTYRSHCSQVYNYHRLLSWDKVRGLHVDIFKVPTCCSCQVDGYRQQFPPLSSIQAKDYSPQSPVINHSHNGYSTINEEDLDYAEESEEDELGLRYPSFNNRETNELYSSSNKVRVKLPGISSSVGPYLSPPDDDEDRYGGYKSSSSSSKKYYSQVSRRRPQHSEARLDLDLAPSETHSDQEPPPPQHHQHHHLQYHRPQEELPSAYDFHRPQVYQPEREQLPLVRDPALSPVSAPVLASPAPPLPMPPMPIKQVPSHHQAHHQQPHHHLHQSTGKVAANRDPASMHHQPPRRPTQQWLPGQRRPFRPSAPLSGSGISRRHYHNRRQSIQ
What is the function of this protein?
Neurotrophin which may function as a ligand for the Toll-related receptors Toll-7 and Tollo (PubMed:22022271, PubMed:23892553).  Binds to Toll-7 and probably acts as its ligand in promoting motor axon targeting and neuronal survival in the central nervous system (CNS) (PubMed:23892553).  Involved in synaptic targeting of ISNb/d motorneurons and also some SNa motorneurons (PubMed:19018662).  In larvae, involved in the negative regulation of the tracheal immune response to bacterial infection perhaps by acting as a ligand for the Toll-related receptor Tollo (PubMed:22022271).  May be involved in the normal development of specific neurons at the neuromuscular junction (PubMed:24124519).
What are the official names of this protein?
Neurotrophin 1, Neurotrophic factor 1, Protein spaetzle 2, Protein spatzle 2.
Protein: PUN1_YEAST
Sequence: MRNFFTLFFAAIFSLGALILAIVACAGSTKNYSPINKIYCAELDLSQMKVSTVLPSLSSATLSSLGLPSYINIGLWSYCTVDSSHNIQSCSSPHGIQNFNLSSLVYDNINNNEALELMDSVASVVLPEKLKSKMTYYNNLVKCMFITILIGIVLTFVNLVFNVLRWIIHIRPLTWFGAFFSFFAFAALLVSIGSCLGTYSYIKYILKHNYSDYGISMSIGRNYQGLMWGAVVGALLNFILWCSVRSRPTVIYANAPIEEKPLI
What is the function of this protein?
Contributes to the wild-type cellular response to nitrogen stress through signaling pathways that regulate the expression of genes involved in amino acid biosynthesis.  Required for wild-type filamentous growth, cell growth, and cell-cell adhesion.
What are the official names of this protein?
Protein PUN1, Plasma membrane protein up-regulated during nitrogen stress 1.
What is the protein family that this protein belongs to?
Belongs to the SUR7 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to punctate patches in the plasma membrane that show extensive colocalization with SUR7.
Protein: CH10_LEPBL
Sequence: MASIKPLGDRVLVEPRQEAEEKIGSIFVPDTAKEKPQEGKVVEIGSGKYEDGKLVPLEVKVGDTVLYGKYSGTEIKSEGKEYLIIRESDILAVVKK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPX_HAEIN
Sequence: MNDSILEPKHRGNVREIAAIDLGSNSFHMIVARIVNGSIQVLSRLKQKVKLAEGLDENAVLNQEAITRGVNCLALFAERLQGFPMENVNVVGTYTLRRAVNNDEFLRQAAKVFPYPINIISGQTEAKTIYAGVCHTQPEKGRKLVIDIGGGSTEMIIGDDFTPLMAESRHMGCVSFATQFFTDGIISPENFQRARQSAVNKIEDLGLEYRKLGWQSVLGSSGTIKTVAQVIATNLDPNGTITAERLNALIEQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFHIQQMRYSDGALREGVIYSLEKNFQVADIRASTA
What is the function of this protein?
Degradation of inorganic polyphosphates (polyP).  Releases orthophosphate processively from the ends of the polyP chain.
What are the official names of this protein?
Putative exopolyphosphatase, ExopolyPase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YMH1_CAEEL
Sequence: MIGSVRVLVLLLAFIVTASAIGYSGGGYQPHSCDGDWPEKFPEAPKGFQFRCKCPCKCPPKSPTTTSISTSTVSTTPERLTKPYEETDTPIPTHSSPSTSTSTSTSTSTSTSTSRSTSTVTPTTRSSTTTTATSTPTSSSKATTTSAQITQPEIPQAAPGTVLKGEEFPVKQDGLGDGGVVHGPGTTFWIRSPTPPNIPLLVGGQSRLATVRPDSPYASDAALNPLNGGAGDMEFGIKNVGTPKTPRAVINPDA
What are the official names of this protein?
Uncharacterized protein F58A4.1.
Protein: FLIE_ECO8A
Sequence: MSAIQGIEGVISQLQATAMSARAQDSLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: CBPA3_RAT
Sequence: LMGVIYSTLAIAPVQFDREKVFRVKLQDEKQASILKNLTQTIELDFWYPDAIHDIAVNMTVDFRVTEKESQTIQSTLEQHKMDYEILINDLQEEIDKQFDVKEEIAGRHSYAKYNDWNKIVSWTEKMVEKHPEMVSRIKIGSTVEDNPLYVLKIGRKDGERKAIFMDCGIHAREWVSPAFCQWFVYQAAKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTKDRMWRKNRSKNPNSTCIGTDLNRNFDVSWDSSPNTDNPCLSVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLFPYGYTIKLPPNHQDLLKVARIATDVLSSRYETRYIYGPIASTIYKTSGSSLDWAYDLGIKHTFAFELRDKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKHTS
What are the official names of this protein?
Mast cell carboxypeptidase A, Carboxypeptidase A3, R-CPA, RMC-CP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
Protein: COBQ_GRABC
Sequence: MIQGTGSSVGKSLLVAGVSRALTRRGLVVRPFKPQNMSNNAAIAADGGEIGRAQALQARACRISPSHHMNPVLLKPQSEIGAQIVVQGKVHGQATARAYQAMKPQLLGTVLESFGILRKQADIVLVEGAGSASEINLRAGDIANMGFARAANVPVVIAGDIDRGGVIAALVGTKTVLDPDDAAMVRGFLVNRMRGDPSLFAEGMRLIEQQTGWEALGLVPHCEAARALPAEDAADLLRGLSAPTRSGNTVIAVPMLPHIANFDDLDPLAAEDSVTLVMVPPGQPLPVADAIIIPGSKTVIADLAALRHHGWDIDILAHRRRGRSIIGLCGGYQMLGRAIHDPQGFEGPAGSAAGLGLLEIETVLEPHKILTSRSGHLFNHDVPVSGYEMHMGITTGSGLRRPLLSLGPDAPEGCVSADGVVMGTYLHGLFHGGAFRRHLLATLDVSSHGGDHEDAVEHALDALADHMEAHVAIDRLLALSA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: GTRP_LOTGI
Sequence: MKVLVTALIISFSTAVLTVPVSIITAPLSVETIPGSSLDSTKVLGKLEAAYAQYGADSTSFKNSLQNIINAYMSIAADYEAQAGILEVRADIAEAAKNDVLATELEIKGDALEALAEGYTKTAEMLQEFLKLISEHEHKLSVVFREVKSGMIGTAAMESRLRPQATSSLPATGGQPSTGGKPTTGGQPTTGGQPSTGGQPSTGGQPTTGGQSITGGQPTTGGQPTTGGLPTTGGQPSTGGQPTTGGQPTTGGQPSTGGQPSTGGHQQLGVNQPEETPAPNRQLKMFRHYSKVCWQI
What are the official names of this protein?
Glycine and tyrosine-rich protein, Uncharacterized shell protein 7, LUSP-7.
Protein: NOX4_MOUSE
Sequence: MAVSWRSWLANEGVKHLCLLIWLSLNVLLFWKTFLLYNQGPEYYYIHQMLGLGLCLSRASASVLNLNCSLILLPMCRTVLAYLRGSQKVPSRRTRRLLDKSKTLHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFLELNAARYQNEDPRKLLFTTIPGLTGVCMVVVLFLMVTASTYAIRVSNYDIFWYTHNLFFVFYMLLLLHVSGGLLKYQTNVDTHPPGCISLNQTSSQNMSIPDYVSEHFHGSLPRGFSKLEDRYQKTLVKICLEEPKFQAHFPQTWIWISGPLCLYCAERLYRCIRSNKPVTIISVINHPSDVMELRMIKENFKARPGQYIILHCPSVSALENHPFTLTMCPTETKATFGVHFKVVGDWTERFRDLLLPPSSQDSEILPFIHSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTPFASILNTLLDDWKPYKLRRLYFIWVCRDIQSFQWFADLLCVLHNKFWQENRPDFVNIQLYLSQTDGIQKIIGEKYHTLNSRLFIGRPRWKLLFDEIAKCNRGKTVGVFCCGPSSISKTLHSLSNRNNSYGTKFEYNKESFS
What is the function of this protein?
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox.  Regulates signaling cascades probably through phosphatases inhibition.  May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity.  May regulate insulin signaling cascade.  May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
What are the official names of this protein?
NADPH oxidase 4, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, Superoxide-generating NADPH oxidase 4.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, focal adhesion. Cell membrane. Note=May localize to plasma membrane and focal adhesions.
Protein: RS19_SHESR
Sequence: MPRSLKKGPFIDLHLLKKVEKAMEAGDKKPIKTWSRRSMIIPNMIGLTIAVHNGRQHVPVFVTDEMIGHKLGEFSPTRTYRGHAADKKAKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SYC1_TROW8
Sequence: MTLNLYDTLSRRIVTLDCRDRVELYVCGPTVQSPPHIGHMRSGVVYDCLRRWLEYKGLPVLYVRNITDIDDKILASARSTETGETWWQIAYRVSGLFNEAYKALFVKPPDYEPLVTAHIPDIIKAIEILIQKNVAYRAMDGSGNVFFSIDKHPSYGELTDQKDLLIDDCITPGKRDPRDFTLWKEKKDTDPDLAFWESPWGPGRPGWHIECSVMATKYLGTRFAIHGGGVDLRFPHHENELAQARALGAHFADIWMHTGAVNVEGIKMSKSFGNSVLVQDALSKVSPSALRYYFLTAHYRSTLNYTENSLSQACNTWNKLQGCIYRVYDYLEREGYENDFCVSQLNTDFSTSLDNDLNIPEALAIVHNKVREMNRLVDTQADMQYLGNTLSEVVEMLSILCPIDHKITYTSGAQDNSKALLQVLLEARDRARSKGDFYTSDLLRELLAEADISVSDGHVSYGSPRG
What are the official names of this protein?
Cysteine--tRNA ligase 1, Cysteinyl-tRNA synthetase 1, CysRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATL1_CHLAE
Sequence: MNPTFILAALCLGIASATLTFNHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHSFTMAMNTFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVADNGGLDSEESYPYEATEESCKYNPEYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFMFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNSKYWLVKNSWGEEWGMGGYIKMAKDRRNHCGIASAASYPTV
What is the function of this protein?
Thiol protease important for the overall degradation of proteins in lysosomes (By similarity).  Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling.  Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity).  In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin peptide neurotransmitter (By similarity).  In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound peptide ligands presented by cortical thymic epithelial cells.  Also mediates invariant chain processing in cortical thymic epithelial cells.  Major elastin-degrading enzyme at neutral pH.  Accumulates as a mature and active enzyme in the extracellular space of antigen presenting cells (APCs) to regulate degradation of the extracellular matrix in the course of inflammation (By similarity).  Secreted form generates endostatin from COL18A1 (By similarity).  Critical for cardiac morphology and function.  Plays an important role in hair follicle morphogenesis and cycling, as well as epidermal differentiation (By similarity).  Required for maximal stimulation of steroidogenesis by TIMP1 (By similarity).
What are the official names of this protein?
Procathepsin L, Cathepsin L1, Major excreted protein, MEP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Apical cell membrane; Peripheral membrane protein; Extracellular side. Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Secreted, extracellular space. Secreted. Note=Localizes to the apical membrane of thyroid epithelial cells. Released at extracellular space by activated dendritic cells and macrophages.
Protein: PANC_XANOM
Sequence: MIQTLTDLSALRALVNGWKREGLRVALVPTMGNLHVGHYSLVMLARQYADRVVSSVFVNPTQFGPNEDFACYPRTPEADLRGLEDAGCDALWLPDVDTMYPLGTALATPIHAPGVSDVLEGECRPGHFDGVCTVVARLFNQVQPDVAAFGKKDYQQLAVIRQMVADLAFPIEILGGSIVREADGLAMSSRNQYLSAEERPTSANIHKVLLQMRDSYAVGTPRAQVEDAASHALEQAGFRVDYAVVRLPDLSEPGDGHTGAHVALIAARLGSTRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP1_XYLFA
Sequence: MPKHLLIVESPAKAKTINKYLGKDFTVLASYGHVRDLVPKEGAVDPENGFAMRYDLIDKNEKHVEAITKAAKTADSIYLATDPDREGEAISWHISEILKERGLLKDKPMQRIVFTEITPRAIKEAIQKPRMIASDLVDAQQARRALDYLVGFNLSPVLWRKVQRGLSAGRVQSPALRMIVEREEEIEAFITREYWSIHAECAHPAQHFSAKLIKLDGQKFEQFTITDSDTAAAAQRRIQQVAQGRLHITDVTNKERKRRPAPPFITSTLQQEASRKLGFTTRKTMQIAQKLYEGIALGEEGSVGLITYMRTDSVNLSLDALSEIRDIIARDYGTNALPDKPNVYTTKSKNAQEAHEAVRPTSALRTPTQVAPYLSNEEHRLYELVWKRAVASQMIPAILNTTSVDLAAGNEHVFRATGTTVVVQGFLAVYEEGKDNKNAEDDDEGRKLPVMKTGENVPLERILTEQHFTQPPPRYTEAALVKALEEYGIGRPSTYASIIQTLLFRKYVDMEGRSFRPTDIGRAVSKFLASHFTRYVDYDFTAHLEDELDAISRGEEEWIPLMKKFWVPFKELVEDKKDSLDKTDAGSVRLLGIDPTSGKEVSGRIGRFGPMVQIGTVDDEEKPRFASLRPNQSIYSISLEEAIELFKMPRVLGEDQSQQVSVGIGRFGPFAKRGSTYVSLKSEDDPYTIDLARATFLINEKEEIARNRIIKNFENSQIQVLNGRFGPYISDGKLNGKIPKDREPASLTLEEAQQLLIDTGKPARKNFSTKKTATKNETRKQTTKKRTTDAKATKKVSDKPVKKQIKKRIAPNITE
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: RPOA2_FRATW
Sequence: MALENLLHPTNIKIDEYAKNATKFSFEALERGVGYTLGFALKQTMLYSIAGACVTSIKINDGKVTSLEDVIPCDETVADIILNVKSLPVTLAEGVETGTITFELSGSEEEIFSEEAKLSEGLAITEEVFICSYNGGKKLKIEAKVEKGVGFRPAQDNFKDGEFLLDATFSPVVFCDFEIKDARVGRRTDLDKLELNIKTNGNVNCEEALRLAATKIQNQLRNIVDIEEINKGIFVEDPTKDINPILLKHVEELNLTARSSNCLKAVNIRLIGELVQKTENELLKAPNFGKKSLTEIKDKLSELGLSLGTLIENWPQDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha 2, RNAP subunit alpha 2, RNA polymerase subunit alpha 2, Transcriptase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SP2AB_GEOTN
Sequence: MRNEMHLQFSARSENESFARVTVAAFVAQLDPTIDELTEIKTVVSEAVTNAIIHGYNNDPNGIVFISVVIEDGIVHLTVRDEGVGIANIDEARQPLFTTKPELERSGMGFTIMENFMDEVVVESEVNKGTTVYLKKHIAKSKALCN
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: HTPG_BACLD
Sequence: MAKREFKAESKRLLDIMINSIYSQKEVFLRELISNASDAIDKIYYKALTDDSLTFNKDDYYIKISADKENRTLTIADTGIGMTKEELEEHLGTIAKSGSLAFKQENELKDGHDIIGQFGVGFYAAFMVADTVTVITKAHGSDEAHQWESAGADGYTIEPAAKESAGTDVILKLKENTDDENYDEYLDVHRLKAIIKTYSDFIRYPIKMDVAVNKPKEGAENEFEEVQEEQTVNSMVPIWRKNKSELKDEDYEAFYKEKHYGFDKPLAHIHTSVDGAVRYHAILFIPENIPFNYYTKEFEKGLELYSNGVLIMEKCPDLLPDHFSFVKGMVDSEDLSLNISREMLQHDRQLKLIAKNISKKIKNELKSLLKNDREKYESFYQSFGRQLKFGVYNDFGAHKDLLKDLLLFYSSKEKKLVTLEEYVSRMPEDQKYIYYASGDSYDRIEKLPQTELVSEKGYEILYFTEDIDEFAIKMLANYQEKEFKSVSSGDLGIENDDEQNQSDGDDSQYKDLFEEMKKTLDGKVKSVRASKRLKTHSVCLAADGEVTIEMEKILNAMPDNQHVKADKVLEINTNHEVFKTLQNAFDNDKDKFKLYTGLLYNQALLIEGLPIEDPVEFTNDICKVMA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_CAUSK
Sequence: MSNTWDVIVIGGGHAGCEAASASARAGARTLLLTHKRETVGEMSCNPAIGGLGKGHLVREIDALDGLMGRIGDKAGIQYRLLNRSKGPAVRGPRSQIDRKLYREAMQAELFSHVNLDVVAIAVEDLIVEDGVVAGAIDGEGAIYRAPRVVLTTGTFLKGVIHQGEIRISAGRVGDAPSIGLADRLYALGFDMGRLKTGTPARLDGKTIAWDRLEMQAADEQPEPFSFLTTRIDVPQIQCGITYTTAETHKIIAERLGESAVYGGRATGIGPRYCPSIEDKVVRFADKTSHQVFLEPEGLDDDTVYPNGVSTSVSAETQLLFLRTMPGLENVEVIRYGYAIEYDYVDPRELYPTLETKRLPGLYLAGQINGTTGYEEAGAQGLMAGLNAALAVQGREPAVFARDEAYIGVMIDDLVTRGVTEPYRMFTSRAEFRLILRADNADQRLTDRGLALGCVGSVRAEAWAAKKAELEAVRAFARSVTLTPAEANRTGFKVNHDGQRRDVLAMLALPEVTLDRLATVWPQISTWSPMAREQIAIEAAYAGYLDRQRDDVEAFRREEDLRLPADLDYGLVGSLSNEVREKLARVKPLTLGQAARIEGVTPGALTALLAHVRRAKAA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP8_BRALA
Sequence: MPQLNPIPWVFLFFLVWLVLGFLGLQKFTSVVTTTLDDSSEEVEVKSKEYSWPW
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: MIAA1_BACFR
Sequence: MTAKTLIVLIGPTGVGKTELSLRIAEYFKTSIISSDSRQLYAELKIGTAAPTPEQLKRVPHYFVGTLQLTDYYSAAQYETEVMSVLEQLFQQHHVVLLTGGSMMYVDAICKGIDDIPTVDAETRELLLHKYDTEGLDNLCAELKLLDPEYYKIVDLKNPKRVIHALEICYMTGKTYTSFRTQQKKERPFHILKIGLTRDRAELYDRINRRVDQMMNEGLLEEARSVYAHRELNSLNTVGYKEIFKYLDGEWDLDFAIEKIKQNSRIYSRKQMTWFKRDEEIRWFHPEQEKEILSYLQASIK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 1, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 1, DMAPP:tRNA dimethylallyltransferase 1, DMATase 1, Isopentenyl-diphosphate:tRNA isopentenyltransferase 1, IPP transferase 1, IPPT 1, IPTase 1.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HOKE_ECOLI
Sequence: MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYEPKK
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system; if it expressed it could be neutralized by antisense antitoxin RNA SokE.
What are the official names of this protein?
Toxic protein HokE.
What is the protein family that this protein belongs to?
Belongs to the Hok/Gef family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ESO1_SCHPO
Sequence: MELGKSKFSWKDLQYCDKAGTQNSPLRVVAHIDQDAFYAQVESVRLGLDHSVPLAVQQWQGLIAVNYAARAANISRHETVTEAKKKCPELCTAHVKTWKAGESEAKYHENPNPNYYKTCLDPYRHESVKILNIIKKHAPVVKKASIDECFIELTSDVKRIVLEEYPYLKIPSEDSNVALPQAPVLLWPAEFGMVIEEEVVDRTKEDYERDWDDVFLFYAAKIVKEIRDDIYLQLKYTCSAGVSFNPMLSKLVSSRNKPNKQTILTKNAIQDYLVSLKITDIRMLGGKFGEEIINLLGTDSIKDVWNMSMDFLIDKLGQTNGPLVWNLCHGIDNTEITTQVQIKSMLSAKNFSQQKVKSEEDAINWFQVFASDLRSRFLELEGMRRPKTICLTVVSRFLRKSRSSQIPMNVDISTQFIVEATSKLLRQLQQEFDVYPISNLSISFQNIIEVDRNSRGIEGFLKKSNDEIYMSTSVSPSIEGRAKLLNENMRENNSFELSSEKDIKSPKRLKRGKGKGIFDMLQQTAVSKPTENSADETYTCEECEQKITLSERNEHEDYHIALSISRKERYNNLVPPSHDKPKQVKPKTYGRKTGSKHYAPLSDETNNKRAFLDAFLGNGGNLTPNWKKQTPKAISNSSDNMTQLHLDLANSTVTCSECSMEYNSTSEEDILLHSRFHSRVLGGVTVSFQCSPIYRVNYGLSSDCIYSINSESSLIDQRKAEEALSFVNNELSSEPIETIGVDKYTTFLFISDKKCVGLLLAERISSAYIVDELELNNNNSTSSAVYIKNENLRKGFVLGISRIWVSASRRKQGIASLLLDNALKKFIYGYVISPAEVAFSQPSESGKQFIISWHRSRNNGSSKSLRYAVYES
What is the function of this protein?
Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together.  In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase.  The relevance of acetyltransferase function remains unclear (By similarity).
What are the official names of this protein?
N-acetyltransferase eso1, ECO1 homolog, Sister chromatid cohesion protein eso1.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROD2_ARATH
Sequence: MANRFLRPNLIHRFSTVSPVGPPTTIIPEILSFDQPKPEVDLDLSDQARLFASVPISTLLRSTAILHATSIGPMVDLGSWLMSSKLMDTTVTRDLVLRIVKGTFYDHFCAGEDAAAAARRVSSVYESTGLKGMLVYGVEHAEDGGACDENIQKFIETVEAAKTLPSSHLSSVVVKITAICPMNVLKRVSDLLRWQYKNPNFKLPWKLNSFPVFSGLSPLYHTTSEPEPLTVEEERELEKAHERLKSVCLRCQESNVPLLIDAEDTILQPAIDYMAYWSAIMFNSDKDRPIVYNTIQAYLKDAGERLHLALRESEKMNVPIGFKLVRGAYMSSEAKLADSLGYKSPVHDTIQNTHDCYNDCMSFLMEKASNGSGIAVILATHNTDSGKLGARKASELGINKENGKIEFAQLYGMSDALSFGLKRAGFNVSKYMPYGPVDTAIPYLIRRAYENRGMMSTGALDRQLMRKELKRRVMAW
What is the function of this protein?
Converts proline to delta-1-pyrroline-5-carboxylate.
What are the official names of this protein?
Proline dehydrogenase 2, mitochondrial, Osmotic stress-induced proline dehydrogenase, Proline oxidase.
What is the protein family that this protein belongs to?
Belongs to the proline oxidase family.
What are the subcellular locations of this protein?
Mitochondrion.