PharMolix/UniProtQA huggingface dataset:
Protein: ZRAR_SALTI
Sequence: MIRGKIDILVVDDDVSHCTILQALLRGWGYNVALAYSGHDALAQVREKVFDLVLCDVRMAEMDGIATLKEIKALNPAIPILIMTAFSSVETAVEALKAGALDYLIKPLDFDRLQETLEKALAHTRETGAELPSASAAQFGMIGSSPAMQHLLNEIAMVAPSDATVLIHGDSGTGKELVARALHACSARSDKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLDEIGDISPLMQVRLLRAIQEREVQRVGSNQTISVDVWLIAATHRDLAEEVSAGRFRQDLYYRLNVVAIEMPSLRQRREDIPLLADHFLRRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAIERAVVLLTGEYISERELPLAIAATPIKAENSAEIQPLVDVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR
What is the function of this protein?
Member of the two-component regulatory system ZraS/ZraR.  When activated by ZraS it acts in conjunction with sigma-54 to regulate the expression of zraP.  Positively autoregulates the expression of the zraSR operon (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein ZraR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPN10_SCHPO
Sequence: MVLEATMILIDNSEWMINGDYIPTRFEAQKDTVHMIFNQKINDNPENMCGLMTIGDNSPQVLSTLTRDYGKFLSAMHDLPVRGNAKFGDGIQIAQLALKHRENKIQRQRIVAFVGSPIVEDEKNLIRLAKRMKKNNVAIDIIHIGELQNESALQHFIDAANSSDSCHLVSIPPSPQLLSDLVNQSPIGQGVVASQNQFEYGVDPNLDVELALALELSMAEERARQEVAAQKSSEETEDKKMQE
What is the function of this protein?
Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation.
What are the official names of this protein?
26S proteasome regulatory subunit rpn10.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OTSB_SINFN
Sequence: MSCQTQLLSASEAALGEDFLSALSTDLDNWALFLDIDGTLLDLAETPDAVAVPPSLPASLDHLSKKLGGALALVTGRGLDYADQLFSPANFPIAGLHGAERRDPDGRVHKAAETADFERLKAELVAATASWAGVLIEDKGAAVAAHYRLAPDRQLELEQLMEWALYRAGPDWAIQHGKMVVEIRPARANKGDAVAAFLGQPPFAGRRAIAIGDDVTDEAMFRTVNRLGGLSIRIGPPVPASEALGSIPSAEALRGIIAALALLNI
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
What are the official names of this protein?
Probable trehalose-phosphate phosphatase, TPP, Trehalose 6-phosphate phosphatase, Trehalose-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: TBD_MACFA
Sequence: MSIVTVQLGQCGNQIGFEVFDALLSDSHSSQGLCCKRENEAYQASCKERFFSEEENGVPIARAVLVDMEPKVINQTLSKAAQSGRWKYGQHACFCQKQGSGNNWAYGYSVHGPRHEESIMDLIRKEVEKCDSFSGFFIIMSMAGGTGSGIGAFVTQNLQDQYSNSLKMNQIIWPYGTGEVIVQNYNSILTLSHLYRSSDALLVHENDAVHKICAKLMNIKQISFSDINQVLAHQLGSVFQPTYSAESSFHYRRNPLGDLMEHLVPHPEFKMLSIRNVPHMSENSLAYSTFTWAGLLKHLRQMLISNAKMEEGIDWHARPPLSGLPSLGKMSLNKDLHFNTSIANLVILRGKDVQSADVEGFKDPALYTSWLEPVNAFNVWKTQRAFSKYEKSAVLVSNSQFLVKPLDMIVRKAWNMFASKAYIHQYTKFGIEEEDFLDSFTSLEQVVASYCNL
What is the function of this protein?
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
What are the official names of this protein?
Tubulin delta chain, Delta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Note=Associated with centrioles. Both cytoplasmic and nuclear. In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head.
Protein: PYRE_LISMF
Sequence: MSIEKQVAEQLLEIKAVFLKPNEPFTWASGIKSPIYCDNRLTLGFPKVRQFIAKSLAEKIKQTFGEVDVVAGTATAGIPHAAWVSDLLDLPMVYVRSKAKEHGKGNQIEGPISKGQKVVVIEDLISTGGSSLKAVEALEEAGAEVVGIAAIFTYGLAKGKQLLEESGTKLVTLTNYDELIEVALNENYVTGEDMETLKEWKKNPENWGK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RLMH_THEM4
Sequence: MKIEVIVPGKISKHLKSAFDFYLDKLKRFCDLKISFVRLGGDINKTSKSVILNNEEKEILNKLKGRSFVLLDLYGKQIDSLEFSSLLKNKLLEGNLCFVIGGPLGISENLRRMSEKRISLSKLTFTHEMALILLLEQLFRGFKIINNEKYHY
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERM_BACIU
Sequence: MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQVLNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYGFAKRLLNTKRSLALFLMAEVDISILSMVPREYFHPKPKVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYKLFNK
What is the function of this protein?
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.
What are the official names of this protein?
rRNA adenine N-6-methyltransferase, Erythromycin resistance protein, Macrolide-lincosamide-streptogramin B resistance protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: UPPP_COREF
Sequence: MNEQTYLLASAVEPVAAENMSWTQTLVLSVVQGLTEFLPISSSGHLRIISELFWGADAGASFTAVVQLGTEAAVLVYFAREIWQILTGWFAGVFNKDRRGRDYKMGWMIIVATIPVVVLGVLGKDLIRDALRNMWITATVLVLFSFVFILAEKVGKKDRGYDELNMRDALVMGFAQCLALIPGVSRSGGTISAGLFMGLNREVAAKFSFLLAIPAVLGSGLYSLPDAFDPSTGQAASGLQLTIGTLVAFLVGYASIAWLMKFVANHSFSWFAAYRIPAGLLVMLLLWLGYLNP
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAA_VIBA3
Sequence: MTEKLPLALFLMGPTASGKTDLAIRLRQKYPVEIISVDSALIYKDMDIGTAKPDAGELALAPHRLIDILDPSEAYSAADFRRDAISEMNKIVAEGKIPLLVGGTMLYYKALLEGLSPLPAADQEIRKQIEAESIEQGWQALHDQLREIDPVSAERIHPNDPQRLSRALEVYRISGKTLTELTQTKGDSLPFRVKQFAIAPKERKELHRRIELRFEKMIEAGFEDEMKALYAREDLHPELPSIRCVGYRQMWDYLDGNCDLDEAVFRGVCATRQLAKRQITWLRSWDDLTWLDSENIEQALETLSDAIASD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: YCB7_SINSX
Sequence: MSTTLPTILMLVVGLSTLALAILRRVQSGRSPVVLTYGDDAEGFAGRLFRLIVAALVIHLLAVAMLPASVDAALGRIPALDTPILHAVGLALMTLGGGLTMLSQWAMRHSWKIGIPEKQDAPLVTSGLYAFSRNPIYVGMVTALIGTVMAVPNVISVALALSAWISISYQIRMEETHLAKVFGDAYGAYCRRVRRWV
What are the official names of this protein?
PEMT/PEM2 methyltransferase family protein, ORF7.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HV374_HUMAN
Sequence: MEFGLSWVFLVAILKGVQCEVQLVESGGGLVQPGGSLRLSCAASGFTFSSYWMHWVRQAPGKGLVWVSRINSDGSSTSYADSVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCAR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 3-74.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: RBSD_ALISL
Sequence: MKKNTLLNAELSYIIASLGHTDEITICDAGLPIPDRSQRIDLALIQGIPTFIDTVKATLAEMQIEGVIVAQEFKTVSPQLHDELMTLVQIEEELRGKPITISYIPHEEFKSHSHQSKAIVRTGECTPYANVIFQSGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMKX_MOUSE
Sequence: MKRWQACQDLRSNTFEDAALTEHYEILTTLGQGTFGEVKLASHLVTQTKVAIKILPKSRKNSLVQPEIEIMKSLDHPHIIKLLHIIDTTRNIFIVLEHAVGGELMSRIEEFGYLAEVECHRLFKQLVYALQYCHEKGIVHRDLKPENILLDHRGNVKLTDFGLGTKIIMGQKLVTFCGTLPYCAPELFEDRGYDGRATDVWSLGVVLYFMATGCLPFNGYSYEAIKQKIIAGKYPRSFSLSPELWEVIAKLLTVNPGERPTVHDIARFKWLKPDNEASPASLGENIESHPDPSIMVLMGVMGYNPGEIRESLREKKFDQVMATYLMLKQQSAWENKTTKKPDPRLCDRMLRSTEPTIKNQTSVRRASSVPTHSTFSLPNESESLEKGKRTTMSHSMPPTRNCFNEETTPLHSICPQLVQKAHYRRSIWGETEISDTSEESSTGESLEHPSLKIHTLQTSMGVSKAGSTYSKSKGSSQCVSSHHTSVEEDQCEGTNISREINPPLSPVSPQENLMGQLHIVTTAGSMDIMNTQVTSPPFSRKEAKGEGPALQQRESRPSSPNTLQGHLHGRRQTVPQAPFQRRVWRTLRNGLIRGLRTLCCCLPIERRVHPTNNRDLAVSQKSHGGSHGIRAFRGTVLPEK
What is the function of this protein?
May play a role in sperm motility, especially in the regulation of flagellar function.
What are the official names of this protein?
Sperm motility kinase X.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Smok subfamily.
Protein: IMAND_OCEGH
Sequence: MKITDAKVFVGGPGKNYVTVKVMTDSGVYGLGDATLNNRETLPAKYLTDYLVPNLIGMDPRRSEDIWQFLYRGAYFRRGPVAMAAFGAIDMALWDIKGKLADMPLYQLFGGKSRDGAMVYGHATGADLEDLMDSIAHYVEQGYKAVRVQCGIPGMPTASYAVPEERGASKHYISDFSGIRPKTEIWDSGKYLRWMPGALMAIRERFGPDLHILHDVHHRLTPREAAQFAKAVEPVDLYWLEDPTPAEDQAALRLVRQHSTTPIAIGEVFNSIWECNKLIEEELIDFIRVAATYAGGITHVKRIVDLAGLHHVRTGFHGAPSHSPLCMAAHAHLNAWAPNFGIQEYLVLGTPDCDALFPSDHRMEDGMVHVSDAPGLGVDFDEAEAARYEYRPGSHPVVRLTDGTMWDY
What is the function of this protein?
Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding.  May have evolved a divergent function.
What are the official names of this protein?
D-galactonate dehydratase family member OG2516_05608.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: KCRM_BOVIN
Sequence: MPFGNTHNKHKLNFKAEEEYPDLSKHNNHMAKALTLEIYKKLRDKETPSGFTLDDVIQTGVDNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGFKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYALPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
What is the function of this protein?
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e. g.  creatine phosphate).  Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
What are the official names of this protein?
Creatine kinase M-type, Creatine kinase M chain, Creatine phosphokinase M-type, CPK-M, M-CK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_DEHMC
Sequence: MLTSRAEIILRSIVRQYITKAVPVSSSSILEDCGLDICSATIRNEVVRLEIEGYILRPHHSAGSIPADKGYRYYVESLKDVELPTNDKFLIRHLFHQVEKEMEEWLNLTVAVLSQRVQSMAVVTMPRQTQGKVHHIELVSLQDNLVLVVLILRGAKVKQQLVNFENVVSQPELTLISNRLNDAYDGLTRFQIEQKPLGLNHDELKVKDSLVKMMRGEDEQESREPFFDGLHYMLEQPEFHQNQRAQEIMQLLEQKKLSKMIVPPMPFNRGVQVYIGQENASAEIRDYSLIVSQYGIPDEAVGTIGVIGPTRMAYERALSAVSYLSLVMSTLVAELYGKAPVDKDE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: GBRL1_CAVPO
Sequence: MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
What is the function of this protein?
Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.  Involved in formation of autophagosomal vacuoles.  While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.  Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover.
What are the official names of this protein?
Gamma-aminobutyric acid receptor-associated protein-like 1, GABA(A) receptor-associated protein-like 1, Glandular epithelial cell protein 1, GEC-1.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle membrane; Lipid-anchor. Cytoplasm, cytoskeleton. Endoplasmic reticulum. Golgi apparatus.
Protein: OM25_BRUME
Sequence: MRTLKSLVIVSAALLPFSATAFAADAIQEQPPVPAPVEVAPQYSWAGGYTGLYLGYGWNKAKTSTVGSIKPDDWKAGAFAGWNFQQDQIVYGVEGDAGYSWAKKSKDGLEVKQGFEGSLRARVGYDLNPVMPYLTAGIAGSQIKLNNGLDDESKFRVGWTAGAGLEAKLTDNILGRVEYRYTQYGNKNYDLAGTTVRNKLDTQDFRVGIGYKF
What are the official names of this protein?
25 kDa outer-membrane immunogenic protein.
What is the protein family that this protein belongs to?
Belongs to the Omp25/RopB family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS8_RICAH
Sequence: MSMTDNVADMLTRIRNAYKSKLINVSFPSSKIKTSILDVLQKEGYIKDYVTTQKNNISYAEVALKYSVNGDASICEIHRVSKPGKRVYSAIKALKGYYNNMGIYILSTPYGVMSDREAHIKNVGGEVICKVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SGSL_TRIAN
Sequence: NEQANLRLSEANSGTYKTFIGRVREELGSETYRLYGIPVLKHSLSNSNRFYLLTLTSNQDESITLAIDVEDMVAVAYQPAGSHESYFFLNAPQIAFHTLFTDTHQNVLNFDNTFKSLENAAGTTRQTIVLGVDPLDFAISNLFNADPKLLPLSFLVIIQMVLEASKFRFIEQSVAYSFKNEKTFLPDLAIVSLEDNWSEISLQIQASTSLQGLFGSVVELYNSNNELIEVDSIYYPIILANVALQLYHCQVSTGDNECLVETRTTRISGRDALCVDVAGALTSDGSRLILYPCGQQVNQKWTFHSDGTVRSLGKCLATNNSKFGNLVVIYDCSKLAAEDISWDVSVGGTIMNPNYEDLALTSNKATRSTNLTMEVNTYSASQGWRVGNYVQPIIGSIVGLDDMCLEATDGNTNMWLEECVPNQREQSWALYSDGTIRVDDNRELCVTASSSTYDNWKVITILNCDGSNNQRWVFLADGSISTPGNQRLAMDVARSDVDLKKIILHRPHGDLNQQWVLFY
What is the function of this protein?
Seed lectin similar to type 2 ribosome-inactivating proteins (PubMed:23897472, PubMed:11375527).  The Aalpha and Abeta chains constitute the rRNA glycosidase domain and the B chain the carbohydrate-binding lectin domain (PubMed:23897472).  Is predicted to have no glycosidase activity and, hence, to be non-toxic, due to small changes in both the nucleotide binding and carbohydrate binding capabilities (PubMed:23897472, PubMed:11375527).  Binds galactose and derivatives with a preference for the beta-anomeric forms (PubMed:8799450, PubMed:10877067).  Binds prophyrins (PubMed:10877067).  Has hemagglutinating activity towards rabbit and human erythrocytes (PubMed:8799450, PubMed:10877067).
What are the official names of this protein?
Seed lectin, SGSL.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the ribosome-inactivating protein family. Type 2 RIP subfamily.
Protein: SYE_LISMF
Sequence: MSETKRVRVRYAPSPTGFLHIGNARTALFNYLFARHNDGDFIIRIEDTDAKRNIADGEESQMTNLKWLGMDWDEGVDVPGKYGPYRQSERQSIYEPLIQQLLDEGLAYKCYCTEEELDAEREKQKANGEMPRYSGKCRHLTKEQQAEKEAQGFKPSIRFKVPANETITFNDMVKDDVSFESNGIGDFVIAKKDGIPTYNFAVAVDDHLMEISHVLRGDDHISNTPKQILIYNAFGWEPPIFGHMTLIVNESRRKLSKRDGSIIQFIEQYRDLGYLPEALFNFIAMLGWSPEGEEEIFSKEEFIKMFDPKRLSKSPALFDNVKLTWVNNQYVKKLPLNDVVELSLPHLQKAGVVSAELDQAELDWVHKLVSLYHEQMSYGAEIVPLSEMFFADAESITFDEEETAVLAEETVPTVISAFKKELEALEVLEAAEVKAAIKRVQKETGVKGKGLFMPIRIVTTGEMHGPELPLAIEVLGREKVLNRLDTWLKNN
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_STRA3
Sequence: MKKTGILNSHLAKLADDLGHTDRVCIGDLGLPVPNGIPKIDLSLTSGIPSFQEVLDIYLENILVEKVILAEEIKEANPDQLSRLLAKLDNSVSIEYVSHDHLKQMTQDVKAVIRTGENTPYSNIILQSGVII
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMS1_HUMAN
Sequence: MKEVVYWSPKKVADWLLENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLCRVSSDNGQRLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIPTPDGSFSIKIKPNGMPNGYRKEMIKIPMPELERSQYPMEWGKTFLAFLYALSCFVLTTVMISVVHERVPPKEVQPPLPDTFFDHFNRVQWAFSICEINGMILVGLWLIQWLLLKYKSIISRRFFCIVGTLYLYRCITMYVTTLPVPGMHFNCSPKLFGDWEAQLRRIMKLIAGGGLSITGSHNMCGDYLYSGHTVMLTLTYLFIKEYSPRRLWWYHWICWLLSVVGIFCILLAHDHYTVDVVVAYYITTRLFWWYHTMANQQVLKEASQMNLLARVWWYRPFQYFEKNVQGIVPRSYHWPFPWPVVHLSRQVKYSRLVNDT
What is the function of this protein?
Major sphingomyelin synthase at the Golgi apparatus (PubMed:17449912, PubMed:14685263).  Catalyzes the reversible transfer of phosphocholine moiety in sphingomyelin biosynthesis: in the forward reaction transfers phosphocholine head group of phosphatidylcholine (PC) on to ceramide (CER) to form ceramide phosphocholine (sphingomyelin, SM) and diacylglycerol (DAG) as by-product, and in the reverse reaction transfers phosphocholine from SM to DAG to form PC and CER.  The direction of the reaction depends on the levels of CER and DAG in Golgi membranes (PubMed:14685263, PubMed:17449912, PubMed:14976195, PubMed:17982138, PubMed:19454763).  Does not use free phosphorylcholine or CDP-choline as donor (PubMed:14976195, PubMed:14685263).  Regulates receptor-mediated signal transduction via mitogenic DAG and proapoptotic CER, as well as via SM, a structural component of membrane rafts that serve as platforms for signal transduction and protein sorting (PubMed:14976195, PubMed:17449912, PubMed:17982138).  Plays a role in secretory transport via regulation of DAG pool at the Golgi apparatus and its downstream effects on PRKD1 (PubMed:18370930, PubMed:21980337).
What are the official names of this protein?
Phosphatidylcholine:ceramide cholinephosphotransferase 1, Medulla oblongata-derived protein, Protein Mob, Sphingomyelin synthase 1, Transmembrane protein 23.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: LAX2_ORYSJ
Sequence: MVPARSLAHPHPHLVRRRRDHAAAAHGATARCDDDDDGVVTPRGPTRYMAQEPINHHQHQHDPPKQPPPREADDDHHRIQEREPLPPPTTTTRNQRLQLQLGGDGHHNHHHHHHQEVAGTSGSSSGGSSSNNGGGGTRDWLRLATGPASPGASAGSDHDLFPSTTTTAPAPQPPTPTPTPTPTPTPRHHHHDVLVLPGMPPPGSFLRPGPAMPGIPQASIPTHMLRAAPPWLPPWSPVAAPPPLLPFPHQHRAFYAAPPTTTPPASSGFDAIRVVLPPSAVAAAAGVWFVLQAAPLQGREPFLPQIPRSYLRIKDGRVTVRLLTKYLVNKLGLEDESEVEITCRGRQLLPILTLQHVRDSIWCRRDAVSPSAAPDIPTADHHQHIMVLQYGRRP
What is the function of this protein?
Involved in the regulation of shoot branching by controlling axillary meristem (AM) formation.  Functions in association with LAX1 to regulate the process of AM formation.  Possesses transactivation activity in yeast.
What are the official names of this protein?
Protein LAX PANICLE 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASB11_PONAB
Sequence: MEDGPVFYGFKNIFITMFATFFFFKLLIKVFLALLTHFYIVKGNRKEAARIAEEIYGGISDCWADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQFEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLLCEGPPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 11, ASB-11.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: PLSX_HELPJ
Sequence: MKIVIDLMGADHGVLPIIEGVSRALENKSFSVVLVGDKDKATPFISKELASKVEMIHTQDYIKMEEAATEAIKRKESSIYLGMDILKNGADALISAGHSGATMGLATLRLGRIKGVERPAICTLMPSVGKRPSVLLDAGANTDCKPEYLIDFALMGYEYAKSVLHYDSPKVGLLSNGEEDIKGNTLVKETHKMLKAYDFFYGNVEGSDIFKGVVDVVVCDGFMGNVVLKTTEGVASAIGSIFKDEIKSSFKSKMGALMLKNAFGILKQKTDYAEYGGAPLLGVNKSVIISHGKSNARAVECAIYQAISAVESQVCLRITQAFESLKSQSFESQSDQQDA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.