PharMolix/UniProtQA huggingface dataset:
Protein: PA2BA_BUNCA
Sequence: NLYQFKEMIRYTIP
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini and exhibits indirect hemolytic activity against human erythrocytes.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 T1-1 A chain, svPLA2, Phosphatidylcholine 2-acylhydrolase T1-1 A.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDUF7_DICDI
Sequence: MFRSITQRVIRNNCYKQSTKSITSSTSFINNSLSYTTTSNENDIKDKNEEHDHRAKGKGRELLLSFDKSGLAQFPKQVFKNRKYPITDFEKYLQDITKVRGPMSIDTFIKEVLTNPKYGYYMNKDVFGKGGDFITAPEVSQLFGEMIGIWCVATWEAMGKPKKLQIVEMGPGRGTLMKDILRSTKVFKEFYDSISVHLVEASPANKKTQKQNLLYFKDKAINFDHKTIGETPNGIKVTWVGKLEEVPTDIPTLFLAQEFFDALPIHVFRFSREKNDWCEVLVDEDITEHGEYYLRFVQSKGPTLMTTAVKHLLPEFGLDGYQVELGLAGLAISQQIANRIDKSGGAALIIDYGYDKIVKSSLQAIRDHEFVDILDKPGTADLSVWVDFQTIRKTVKLLKNKSTAIGPVDQGIFLKEMGIEHRLAQIGRKLDSNEKFEELVMGYKKLVDPKEMGTNYKVITICDKNITPIGFSTSKTYDDEDLMI
What is the function of this protein?
Involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (PubMed:16507593, PubMed:20406883).  Acts as an arginine methyltransferase and probably acts by mediating arginine methylation of ndufs2 (By similarity).
What are the official names of this protein?
Protein arginine methyltransferase NDUFAF7 homolog, mitochondrial, Mitochondrial dysfunction gene A, NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the NDUFAF7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MSHA_MYCSK
Sequence: MRLATDQLGRPPQRVAVLSVHTSPLAQPGTGDAGGMNVYVLQSALHMARRGVEVEIFTRATTSADPPVVRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFTAGVLRAEATHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAEGDSPEPPLRAVGEQQVVDEADRLIVNTELEAEQLVSLHNADPSRIDVVHPGVDLDTFTPGDRAAARAALGLDPRETVVAFVGRIQPLKAPDILLRAAAKLPDVRVLVAGGPSGSGLAAPDNLVALADELGISERVTFLPPQSREDLVRVYRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGVTGALVDGHDVGDWAHTIDSLLSRGPATMRRAAVEHAATFSWAHTVDDLLASYGRAISDYRDRHPHADETLSRRTARRFSRRRGVRA
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: QUEA_SORC5
Sequence: MRCELLDYELPEALIASRPPEERDGARLLLVDRGRRAGEVEHAAIRDLDRYIERGALVIVNDTKVVPARLFGRKRGTGGQVELFLLHRLDGAPAGAEDLGGGPQESAPRSERWRAMGRASKPIRPGSVLDIERDGALVAEVLERAEDGVLTVQLSSPAGLSVAAAIDAYGHVPLPPYLGRGDDASDRERYQTIFARVPGAVAAPTAGLHLSPGLVERLRANGVEIASVTLHVGLGTFQPVTVDDLDLHPMHAEVYSIPDATAGAIAGARARGAPVIAIGTTVVRALESAADPARAGLVQAQSGETRLLIQPGYRFRVVDALLTNFHLPRSTLLALVFAFAGRERTLLAYRAAIDAGYRFYSYGDAMLIRGVDAP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPX_CHLMU
Sequence: MGKTKKRKQSITLIEMMVVITLIGIISGALAFNMRGSLQKGKVFQTEQNCARVYDVLMMEYASGNLSLKEVIANKETLLDNSAWCKEGKKLLKDAWGEDLIVKMNDRGDDIVVLSKKLKSEQRG
What are the official names of this protein?
Putative outer membrane protein TC_0858.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: RL36_AQUAE
Sequence: MKVRSSVKKRCAKCKIIRRKGRVMVICEIPSHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RECX_CHLL2
Sequence: MADHSKNEAAAYALKLLSLRSHSRFELAGKMLRKGYRKELVEEVLDYLVQKQLIDDEAFAKELIGSRSRRKPVGKRKMQFDLIRKGVPENIADALLKEYDGAELCYRAGVRKAAALKGRDESERKKKLEVFLRNRGFDWPVIKETITRLFQTGPECEND
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_SALPA
Sequence: MVSLEKNDRVMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCLNSGIRRIGVITQYQSHTLVQHIQRGWSLFSEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIKEATAFGVMAVDESDKIIDFVEKPANPPAMPGDASKSLASMGIYVFDADYLYELLAADDKDDASSHDFGKDIIPKITREGMAYAHPFPLSCVQSDPQAEPYWRDVGTLEAYWKANLDLASVTPELDMYDQNWPIRTHMESLPPAKFVQDRSGSHGMTLNSLVSGGCIISGSVVVQSVLFPRVRINSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACIIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLQVKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: Y183_TOLAT
Sequence: MAICDWPEDERPREKLLQRGASALSDAELLAIFLRTGVAGCNAIELARNLLQEFGSLRALLGAEQAQFCQAHGLGPAKYVQLQAVLEMSNRYLSECLQRGDSLTSPQLVRRYLQAQLRDRPREVFAMLLLDNQHRVLRFCELFFGTIDAASVYPREIVQTVLKHNAAAVILCHNHPSGVAEPSHADRHITERICDALRLIDVRVLDHFVIGDGDPVSFAERGWL
What are the official names of this protein?
UPF0758 protein Tola_0183.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: CETZ5_HALVD
Sequence: MKVLCFGMGQAGGNVLDALLRYEQRTNADYVVDAVAYNTASADLRGLDLVPEENRILFGADEVSGHGVGADNELAAELAERDSRQLLRGTDGAPTSTADAFLIFAGLGGGTGSGAAPVLAKHLNRIYEQPIYGVGILPAADEGALYSRNAARSLKALVDVTDHVFAFDNGAWAESGEDVAQAHDTMNEVLVRRLGILFASGEVAESGTVAESVVDSSEVINTLRGGGISTIGYAASELPESDGGGGFSIKGLLGGDSSSTDELDSINRITTQTRKAVLGQLTLPCDVDSASRGLVVVSGPPEWLNRKAVERSRTWVEEQTGSMEVRGGDYPLSESNHVGVLVLLGDVSRSDRVAEIRSTAVEAEQNRRERIASDAADREDGTEAVVDDRLDSLF
What is the function of this protein?
Involved in cell shape control.
What are the official names of this protein?
Tubulin-like protein CetZ5, Cell-structure-related euryarchaeota tubulin/FtsZ homolog 5.
What is the protein family that this protein belongs to?
Belongs to the CetZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTH7_DROME
Sequence: MRLPWVIFCTVLLLIFTNNSNADIPGCNYYDTVDISYIERQNDSYLYDDIEIPASLTGYYEFRQFGDGSITPIEKHLRACVCSVRPCIRICCPAKNFLANGKCDDGLKEELARFKPYIYFTYMDLQARVPLTDMAIIRDEFFDCDEMIYISDFNYFLEEVSIQIFNKCGLIVWFQDGKFWVTVDLFMEKQDYCLYRHNFDSDFPKSMWIIRHRCTSHISPGSLEILIITMICFVLTIAVYLYIKKLRNVTGKCIVCCIVSRFIQCLIMILDHLNLLNGICSPAGYSSHFFRMASNLWLSVISYHTWKVLTSLNRVDPNYRFLRYNAFVWSTAAIMTGSIYIVNQIWENDPSKWNWLPLVGFIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQTYLQFLRLSIVMGLTWIFNVIPYSARLHIFWEWVGIISEYFHSAFGIVLFVLLVLKRSTWTLMMDS
What are the official names of this protein?
Probable G-protein coupled receptor Mth-like 7, Protein methuselah-like 7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Mth subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3660_MYCTO
Sequence: MLTDPGLRDELDRVAAAVGVRVVHLGGRHPVSRKTWSAAAAVVLDHAAADRCGRLALPRRTHVSVLTGTEAATATWAAAITVGAQHVLRMPEQEGELVRELAEAAESARDDGICGAVVAVIGGRGGAGASLFAVALAQAAADALLVDLDPWAGGIDLLVGGETAPGLRWPDLALQGGRLNWSAVRAALPRPRGISVLSGTRRGYELDAGPVDAVIDAGRRGGVTVVCDLPRRLTDATQAALDAADLVVLVSPCDVRACAAAATMAPVLTAINPNLGLVVRGPSPGGLRAAEVADVAGVPLLASMRAQPRLAEQLEHGGLRLRRRSVLASAARRVLGVLPRAGSGRHGRAA
What is the function of this protein?
May play a role in septum formation.
What are the official names of this protein?
Uncharacterized protein MT3760.
Protein: TOMT_PROCO
Sequence: MGTPWRKRKGITQVGTMSPAIALAFLPLVVTLLVRYRHYFRLLVGTVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSHCEYLSHMGPVKGQILMRLVEEKAPACVLELGTYCGYSTLLIAQALPPGGRLLTVERDPRTAAVAEKLIRLAGFDEHMVELIVGSSEEVIPCLRTQYQLSRADLVLLIHRPRCYLRDLQLLEAHALLPAGATVLADHVLFPGAPRFLQYAKSCGRYRCRLYHTGLPDFPAIKDGIAQLTYAGPG
What is the function of this protein?
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity).  Required for auditory function (By similarity).  Component of the cochlear hair cell's mechanotransduction (MET) machinery.  Involved in the assembly of the asymmetric tip-link MET complex.  Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells.  The function in MET is independent of the enzymatic activity (By similarity).
What are the official names of this protein?
Transmembrane O-methyltransferase, Catechol O-methyltransferase 2, Protein LRTOMT2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Endoplasmic reticulum. Note=Localized to the cell body of the cochlear hair cells, but is not present in the stereocilia. Present but not restricted to the apical cistern, Hensen's body and the subsurface cistern.
Protein: PRIM_HHV2H
Sequence: MGTEDCDHEGRSVAAPVEVTALYATDGCVITSSLALLTNCLLGAEPLYIFSYDAYRSDAPNGPTGAPTEQERFEGSRALYRDAGGLNGDSFRVTFCLLGTEVGVTHHPKGRTRPMFVCRFERADDVAVLQDALGRGTPLLPAHVTATLDLEATFALHANIIMALTVAIVHNAPARIGSGSTAPLYEPGESMRSVVGRMSLGQRGLTTLFVHHEARVLGAYRRAYYGSAQSPFWFLSKFGPDEKSLVLAARYYLLQAPRLGGAGATYDLQAVKDICATYAIPHDPRPDTLSAASLTSFAAITRFCCTSQYSRGAAAAGFPLYVERRIAADVRETGALEKFIAHDRSCLRVSDREFITYIYLAHFECFSPPRLATHLRAVTTHDPSPAASTEQPSPLGREAVEQFFRHVRAQLNIREYVKQNVTPRETALAGDAAAAYLRARTYAPAALTPAPAYCGVADSSTKMMGRLAEAERLLVPHGWPAFAPTTPGDDAGGGTAAPQTCGIVKRLLKLAATEQQGTTPPAIAALMQDASVQTPLPVYRITMSPTGQAFAAAARDDWARVTRDARPPEATVVADAAAAPEPGALGRRLTRRICARGPALPPGGLAVGGQMYVNRNEIFNAALAVTNIILDLDIALKEPVPFPRLHEALGHFRRGALAAVQLLFPAARVDPDAYPCYFFKSACRPRAPPVCAGDGPSAGGDDGDGDWFPDAGGPGDEEWEEDTDPMDTTHGPLPDDEAAYLDLLHEQIPAATPSEPDSVVCSCADKIGLRVCLPVPAPYVVHGSLTMRGVARVIQQAVLLDRDFVEAVGSHVKNFLLIDTGVYAHGHSLRLPYFAKIGPDGSACGRLLPVFVIPPACEDVPAFVAAHADPRRFHFHAPPMFSAAPREIRVLHSLGGDYVSFFEKKASRNALEHFGRRETLTEVLGRYDVRPDAGETVEGFASELLGRIVACIEAHFPEHAREYQAVSVRRAVIKDDWVLLQLIPGRGALNQSLSCLRFKHGRASRATARTFLALSVGTNNRLCASLCQQCFATKCDNNRLHTLFTVDAGTPCSRSAPSSTSRPSSS
What is the function of this protein?
Essential component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA primase family.
What are the subcellular locations of this protein?
Host nucleus. Note=Requires the presence of the primase associated factor to properly localize in the host cell nucleus.
Protein: RL35_BRUSU
Sequence: MPKMKTKSAAKKRFKITGTGKVKAAAAGKRHGMIKRSNKFIRDARGTMVLADADAKIVKQFLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GLR_HUMAN
Sequence: MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
What is the function of this protein?
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis.  Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis.  Plays an important role in mediating the responses to fasting.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Promotes activation of adenylate cyclase.  Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Glucagon receptor, GL-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Is rapidly internalized after ligand-binding.
Protein: OSTF1_CHICK
Sequence: MSKPPPKPAKPGQVKVFRALYTFEPRTPDELYFEEGDIIYISDMSDTNWWKGTCKGRTGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNQVGVNGLDKAGNTALYWACHGGHKDIVDVLFTQANLELNQQNKLGDTALHAAAWKGYADIVEMLLAKGARTDLKNNEKKLALDMATNAACASLLKKKQTAGTARTFK
What is the function of this protein?
Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
What are the official names of this protein?
Osteoclast-stimulating factor 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_SALHS
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVIKSNDVREPFNEDKLRSGMLRALEKRPVSADDVEMALNHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKDFGEEIARLQD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CH10C_PEA
Sequence: ATVVAPKYTAIKPLGDRVLVK
What is the function of this protein?
Seems to function only as a co-chaperone, along with cpn60, and in certain cases is essential for the discharge of biologically active proteins from cpn60.
What are the official names of this protein?
20 kDa chaperonin, chloroplastic, Chaperonin 10, Ch-CPN10, Cpn10, Protein Cpn21.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNY_CLOBK
Sequence: MGPTKYIIIAVVIIIICVILGLYVVDKKAKEKLSEASKEARRLKEEAERDAEAKKKEAILEAKEESHKLRAEVERENRERRNEVQRLERRIIQKEEALDKKSEALENKEEALNKKQQKIEDVETHMEELHEKQRTELERISGLTTEQAKEFLLEQVRKEVKHETAVMIKEIETKAKEEADKRAREVITYAIQRCAADHVAETTVHVVNLPNDEMKGRIIGREGRNIRTLETLTGVDLIIDDTPEAVILSGFDPIRREVARIALEKLIVDGRIHPARIEEMVEKAKKEVEVSIKEEGEQATFETGIHGLHIELIRLLGRLKYRTSYGQNVLKHSIEVSHLAGLMASELGIDPTLAKRVGLLHDIGKAVDHEVEGPHAIIGSEIAKKYRESALVVNAIGAHHGDMEPQSLEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANECEGVEKSYAIQAGREIRIMVKPEVLDDTGCIEMARNIVKQIESELEYPGQIKVNVIRETRAIEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: VPU_HV1VI
Sequence: MSYLLAIGIAALIVALIIAIVVWTIVYIEYKKLVRQRKINKLYKRIRERAEDSGNESEGDAEELAALGEMGPFIPGDINNL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: Y3494_YERPS
Sequence: MSQRDTGAHYENLARRHLERAGLVFQAANVAFRGGEIDLIMRDGDAWVFVEVRFRRNDLFGGAAASITPRKQQRLHLAAAVWLAQRGASFATTSCRFDVVAITGNQLEWLPNAFNTD
What are the official names of this protein?
UPF0102 protein YPTB3494.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: COAE_METCA
Sequence: MLVVGLTGGIGAGKSTVARMFAARGVEVFEADEVAHRLLEPGQPALKAVARAFGSDILGADGRLDRAALRRRVFAESKARKRLEGIVHPLVYAELARLVLGAAGSYCVLSVPLLLETGRRRFVDRLLVVDCPESLQIERVVRRSGLRPEEVRAIMAAQVSRSERLAAADDVIVNAADTAGLEAEVDALHRRYSLLAAA
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANT_ECOBW
Sequence: MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLACGFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSAGKRWPTGVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYNPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL23_HELAH
Sequence: MADIMDIKSILYTEKSLGLQEKGVLVVQTAQNMTKNQLKEVFKTYFGFEPLKINSLKQEGKVKRFRGKLGQRKSFKKFYVKVPEGASIVALGA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: P3C2G_MOUSE
Sequence: MAYSWQTEPNRTEPQEDGSDTQQFHHTNQHLSSRQVRLGFDQLVEEINNKTPLSESEKEEDTYFVPDAPNLGSKWPSIYETHPRYFSEFTSQSPDSSQLRFGKLSAIGFNPAVLPTHQLIHEGASWRNPSGKYHGIEYPRFDALPPSSTGQGECNPQGQSGTKHHNYCGEHEGNLPHHHSSYSIDSIPNREKRRSGDVNLVEPSLEFSKDSFLPRTSENVSVESTEPIGCPIEIVEVPQGSNKNLASFCNKVKKIRESYHASDINSNSGKIWAITTAYPSRLFADTKFRVKISIDNSAQLLLLMPHANYLVKDLIAEILLLCANEPLSPKEYLLSVCGSEEFLQMDHSLGSHKIFQKNKSVIQLHLQKNRDTPGKLSRKSEDDHSPFHLNQLLEFTHIWKISRQCLSTVMKKYNLHVEHLLKPQKDMEEKHLSSMVSGNQHTSQPHVNNVLEEVKNICSVLGCIETKQVSDAVKELNLILQRPSQNFHQNSETSKKGFIERVTAELSRSIYQLIDVYCSSFCTDFQPVHTPGGVSHVHAGLQSHLSFTVCSLHNVPETWAHSYKAFSFSCWLTYAGKKLCQVKSCRPLPVTKSFSLLVNWNEIINFPLEIKSLPRESMLVIKLFGIDSATHSTNLLAWTCLPLFPRQESVLGSRLFSVTLQSEPPIEMIAPGVWDGSQPSPLTLQIDFPDAGWEYLKPESEENRTDHEEPPRECLKHIAKLSQKKSPLLLSEEKRRYLWFYRLYCNNENSSLPLVLGSAPGWDEETVSEMHAILRRWTFSHPWEALGLLTSRFPDQDIREVAVQQLDTLLTDELLDCLPQLVQAVKFEWNLESPLVELLPRRPLQSIRVAHCLYWLLRDAQGEAYFKSWYQELLAALQFCAGEALNEELSKEQKLVKLLGDIGEKVKSASDPQRKDVLKKEIGSLEEFFKDIKTCHLPLNPALCIKGIDRDACSYFTSNASPLKITFINANPMGKNISVIFKAGDDLRQDMLALQIIQVMDNAWLQEGLDMQMITYGCLSTGRAQGFIEMVPDAVTLAKIHLHSGLIGPLKENTIKKWFSQHNHLKEDYEKALRNFFYSCAGWCVVTFILGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGGKNIQHFQDFVELCCRAYNIVRKHSQLILSLLEMMLHAGLPELRGIEDLKYVHNNLRPQDTDLEATSHFTKKIKESLECFPVKLNNLIHTLAQMPALSLAKPAPQTLLQESCILNKTRTIQRVTILGFSKTHSNLYLMEVTCSDNRRSLTKKSFEQFYRLHSQMQKQFSSLALPEFPHWWHLPFTDSDHKRIRDLSHYVEQVLRGSYEVANSDCVLSFFLSEHIQPTLEDSPFVDPGENSLDKSPKVQLLMTYEDSRLTILVKHLKNIHLPDGSVPSAHVEIYLLPHPSEVRRKKTKCVPKCTDPTYNEIVVYDEVLGLQGHVLMLIVKSKTVFVGAVNIQLCSVPLNEEKWYPLGNSII
What is the function of this protein?
Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers (PubMed:9514948).  May play a role in SDF1A-stimulated chemotaxis.
What are the official names of this protein?
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma, PI3K-C2-gamma, PtdIns-3-kinase C2 subunit gamma, Phosphoinositide 3-kinase-C2-gamma.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: YDFD_BACSU
Sequence: MSFPEEKKMKKLPKYRQIVHFIKEKIGNGEWPIGSKIPSQRTLAKDFQVNRSTVITALEELMADGLIEGTMGKGTVVINNTWTLMAKNSAPDWDQYVTSGIQMPSRKIVQEINQSESNTDLIQLSKGELSAEIFPLAVMKEMMGKVSQHMEAFGYEEPKGYLPLREALSNYLKTIGINVSSSSILIVSGALQALQLISMGLLQRGSTVYLDQPSYLYSLHVFQSAGMKLTGLPMDNEGLLPENVHLTRGERGRAILYTNPCFHNPTGILMSKKRREEILAVSENTQLPIIEDDIYRELWIDEIPPYPIKTIDKNGHVLYIGSLSKTLSPGLRIGWIVGPEPVIERLSDIKMQTDYGSSSLSQRVAAEWFTSGHYQQHVEKVRQQLKVRRELALSALETHLKEVATWNIPKGGFFVWIKILPSISMKLLYTKALSKGILINLGSIYAQEKGNYIRLSYAYASLEDLQKGIYELGLMIKELASR
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YdfD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: MIC60_AJECH
Sequence: MLRTSIASSRPLLPSSVCPKAPAQWLCTSRARRVNTATRRYHALARKSNAGRRCPLTPNTATTSQFFQKAASSTSTKPPGPSDADVRSPASPSSRFSLRPESIPKTPQSPPVQGQTSPGSEVLPPDHESSTPPPPLEGPKSSRLRKLLYLFLTAGLAYAGGVWYSLRSDNFYDFFTEYIPYGEEAVLYLEERDFRNRFPHVTKQINRRVTVPKDEGAQVTIPSGSGLSWKVAEEQQEATDMTKKGRRMGTAHANEPTKDIKVAEKAKEEVKSKSAAKKEDVAANIPIQEALEPQPAKAEEKNLEAPRQPAVPAVTAIERLVQDKVDEPVVQDLVKVFNDVISVISADESASKFAGPIAKAKEELQRIGDRIVALKKDAQESAQEEIRNAHAAFDKSAAELIRRIDEVRTQDAAEFREEFESEREKIARSYQEKVNTELQRAHEVAEQRLRNELVEQAIELNRKFLSDVKTLVENEREGRLSKLAELSANVAELERLTAGWSDVVDINLKTQQLQVAVDAVRTTLENSDVPRPFVRELAAVKELASNDEVVAAAIASISPAAYQRGIPSAAQLVDRFRRVASEVRKASLLPENAGITSHAASLVLSKVMLKKQGLPTSDDVESILTRTANFLEEGNFDEAAREMNSLQGWAKLLSKDWLADVRRVLEVKQALEIIETEARLRCLQVE
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.