PharMolix/UniProtQA huggingface dataset:
Protein: USB1_DROME
Sequence: MALVDYGGSSSSASEDEDCTENIQTPALITLKRPALPKAATLLGPKKPKPEEFVEDVVDDPAEHGGRMRSFKHERGNWATYVYVPATACVDQLEEFQTEAIARLEPHLELQPNESLHLSLSRTVVLQYHQIDEFSRSLQSALNSSAGFAATLQGLRIYTNEERTRTFIAAPLDAAFVEKMTAILQPIDQVMLDYRLQQFYDPASFHVSLLWCVGDQETLLNEKLTELKELLDDQDKLCLAVNEVHLKCGNKDFTYSLK
What is the function of this protein?
3'-5' RNA exonuclease that trims the 3' end of oligo(U) tracts of the pre-U6 small nuclear RNA (snRNA) molecule, leading to the formation of a mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.  Participates in the U6 snRNA 3' end processing that prevents U6 snRNA degradation.
What are the official names of this protein?
U6 snRNA phosphodiesterase 1, 3'-5' RNA exonuclease USB1.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. USB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOZ_LISMC
Sequence: MMLYPSIDNLLLKIDSKYSLVTVAAKRARYMQLENDKGVLPSYQSDKFVGKALEEIHAGKLVLQNDDK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: Y7151_DICDI
Sequence: MENSGLLFNNDETIINKKIKKIIYENQYDKPLFYDIDLRKNNKKLIYLLDWFCVVVLLVIGSILLLKVPVRGRLFRLNDESISYPKLEEIIPLGLLIPLVTAVPFAMILLISIIFKRDINDFHHSLLGFLQSISVTILLTGSFKVFIGGLRPSFLEFCKPTKESIVAGNPPVGYGAIYYDRSICTESEFIVNDGLSAYPSGHSSIAASCFGFLALYLLARLKCFDNRGHIIIYLLIIGCLITAGLIGISRVADYRHTFLNVLAGWSIGLLISLSCYRLNFSSLFGRDNHISIHSHWLTYWDYHNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNKKDNINNNSTKTQNNFESYQSPNGIPLNELQN
What are the official names of this protein?
PA-phosphatase related-family protein DDB_G0271516.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YOHO_SALTY
Sequence: MRVAKIGVIALFLLMAIGGIGGVMLAGYSFILRAG
What are the official names of this protein?
UPF0387 membrane protein YohO.
What is the protein family that this protein belongs to?
Belongs to the UPF0387 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: IF3_STRPM
Sequence: MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_FRAT1
Sequence: MGRSRHHNKLKEGIFEAEITALSHDGRGIAKVDGKTTFIPFTLPGEVVKFEYTFTKAKFDEAKVVEYVKKSSNRVNPPCDHFQICRGCSLQHMSTDAQIEHKQQTLINQLKYIGNGVEPENILPPLRTSNTEGYRNKARLGVRYVSKKGKILVGFRERNGRFLADIDKCIVLNPLVGDKITEISSFIETLSIYQHIAQLEIAIDDTRPAMIVRHLEPFTNEDLEKLRSFAQENNYWIYLQSKGPDTIFRLYPQGDVEPKKLSYQPAAGIDIGFEPNDFTQVNNDINKKMIKRAIELLDISENDSIIDLFCGLGNFTLPISQHAKTVIGVEGEPTMVKRAKETADNNNITNVNFYAANLFESFEDKEWFNNFEYNKMLLDPPRAGAQEVCNNIEKFNVKRIVYVSCDTAALARDAGILVNTKGYKLISAGVMDMFPHTMHVESIAVFEKI
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: HFQ_VIBC3
Sequence: MAKGQSLQDPFLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARPVSHHSGDRPASDRPAEKSEE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: DAPA_EXISA
Sequence: MFTGVATALATPFQENGQLNLEAWAALIEDQIKEGVTGLVIGGTTGEGMTITDDEFETLLVRAVEVANGRAVIIAGTGSNNTAVSIEKTKRAAELGAEMAMVVTPYYNKSTQAGLIAHFTAIADASPIPLMLYNVPSRTGVALAPETVGELAEHPRITALKEASGDISVMAQMMAHIPEGFTVYCGNDDQILPYMAWGAQGVVSVLSNVYPGATVALAEALLAGDLQTARTWQIRLLPVIDELFAEVNPIPVKAALQARGFEVGAPRLPLVPMSATAEAKLLSAMEQFNEVRQ
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGH_DICD3
Sequence: MNKSTSTLEYIEKLPLPAEQAEALREKFSASQDLSSLHQALSDGSVVTMQSPDDIPLVSVPRRLELAWEDGLNGGKQLGKDREGRTALQAMPRITRASMFPDAWQTNPMVRWWDMINGRSKPLRHHDKTAEENEAENRWRRVGTLRRYVLLLLTLFQTAIATWYMKTILPYQGWALIDPFAMVHQDVWRTIMQLLPYVLQSGILILFAILFCWVSAGFWTALMGFLQLLIGKDKYSISSTTTGNEPLNPEHRTALIMPICNEDVERVFAGLRATYESVEATGELDHFDIYVLSDSNDPDICVAEQKAWMDLCREVGGAGRIFYRRRRRRVKRKSGNIDDFCRRWGNQYSYMVVLDADSVMSGECLTSLVRLMDANPRAGIIQSAPRASGMDTLYARCQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHTLMEPQYFLQPRQLFPVWPQWRPELAIALFSTTLVLLFLPKLLSVILVCAKGAKSYGGVAKLFISLLVEMLFSVLLAPVRMLFHTVFVVSAFLGWSVQWKSPQRDDDATPWSEAFARHGSQLLLGLVWAGGMAWLDLRFLWWLAPIVFSLILSPLVSVLSSRAGLGLACKRAKLLLIPEESDPPRELVATDEYFRRNRERKLDHGFMHAIFDPSINALTSAMATARHRFSRPIEDMREQRVNDALSRKPQDVDCNLRLALMSDPVTLARLHHRVWSQPDTHSDWRSHYQTLAAPVIKSAQ
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).  Seems to be required for pathogenicity.
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NAGS_SCHPO
Sequence: MQKPSLSQDLIWILKSVQSRRSTKGFLQKHSSLKDGSPNKKSFAQPISSSFLNRISITKIDDVDSLSDNTLYGIGRSINSLARLGIQSVIVPTSNPIGMTSPFKYLENGTVVAKKRKLSIFEELQQQQNRVIRVSEIFSKAGVLTRPSYSSVCQLGPEGPSVENVQGIFQALSSLYTVIVPSSILMPNVIEVPIDGNEVLAGLTYSLHKPNFGFWVDRIVILDKNGGMPCSKRQTGSSHVLINLAQEFDELAKTLPPYHRKNLILVRRCLKMLPDDASALITTPEDAMLTNPVLDKNPLIHNVLTDRSIISCSLPRDRSPITKTTVLRSGVPVYTFLGPKCLTDGSVSWERLWVLINDSFKRTLDMDAYLDRLKNSLAAVIIAGDYLGTAIVTYEQPDGTTNEKVPYLDKLAVSQGAQGSAAISDVMFNVMTDLFPKELIWRSRLTNPVNKWYFERSVGSLKSSKTPWKLFWTGDSHVRNLDRVNQYMSVIDKIQPTWLN
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 6, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: ARLY_MYCA1
Sequence: MSTREGSLWGGRFADGPSDALAALSKSTHFDWVLAPYDIVASRAHTVILYRAGLLSEEQRDGLLAGLDSLAEDVADGSFTPLVTDEDVHAALERGLIDRVGPDLGGRLRAGRSRNDQVATLFRMWLRDAVRRVAAGALDVVGALVAQAAAHPEAIMPGKTHLQSAQPVLLAHHLLAHAHPLLRDVDRIVDFDKRAAVSPYGSGALAGSSLGLDPDAIAAELGFASAADNSIDATASRDFAAEAAFVFAMIGVDLSRLAEDVILWSSTEFGYVKLHDAWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLKAQPLAYNRDLQEDKEPVFDAVAQLELVLPAMAGLVGSLTFDVQRMAALAPAGYTLATDIAEWLVRQGVPFRSAHEAAGAAVRAAEQRAVGLDELTDDELAAISPALTPQVREVLTIEGSVSSRDARGGTAPARVVEQIDTVAATAARLRERLGGPA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAT8_ARATH
Sequence: MAGDGVENAKPPQKQEDLQPHPVKDQLYGITYCLTSPPPWPETILLGFQHYLVMLGTTVLIPTMLVSKIDARNEDKVKLIQTLLFVSGINTLFQSFFGTRLPAVIGASYSYVPTTMSIVLAARYNDIMDPQKRFEQIMRGIQGALIIASFLHILVGFSGLWRNVTRFLSPLSAVPLVAFSGFGLYEQGFPMLAKCIEIGLPEIILLVIFSQYIPHLMQGETCSNFFHRFAVIFSVVIVWLYAYILTIGGAYSNTEINTQISCRTDRAGIISASPWIRVPHPIQWGGAPTFNAGDIFAMMAASFVSLVESTGTYIAVSRYASATPIPPSVLSRGIGWQGFGILLCGLFGAGNATSVSVENAGLLAVTRVGSRRVIQVAAGFMIFFSILGKFGAIFASIPAPIVAALYCLFFSYVGAGGLSLIQFCNLNSFRTKFILGFSIFMGLSIPQYFYQYTTLETYGPVRTSATWFNNIINVPFSSKAFVSGILAFFLDTTLPPKDKTTKKDRGLVWWKRFKSFQSDNRSEEFYSLPLNLSKYFPSH
What are the official names of this protein?
Nucleobase-ascorbate transporter 8, AtNAT8.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FBIB_STRAW
Sequence: MPGLPEVAPGDDLAKLIAAVEPGLVDGDVLLVTSKIVSKAEGRIVRADDREAAIDAETVRVVARRGALRIVENRQGLVMAAAGVDASNTPSGTVLLLPEDPDASARAIRDGLRDTLGVDVGVVVTDTFGRPWRTGLTDVAIGAAGVRVLDDLRGGTDAYGNPLSATVVATADELAAAGDLVKGKAAGLPVAVVRGLPHVIAGDDEAGARAMVRGGRDDMFRLGTSEAVREAVTQRRTVRAFTDEPVDPGAVRRAVAAAVTAPAPHHTTPWRFVLLESAESRTRLLDAMRDAWIADLRGDRKTEESIAKRVRRGDVLRNAPYLVVPCMVMDGSHSYGDARRDAAEREMFVVATGAGVQNFLVALAGERLGSAWVSSTMFCRDVVRRALGLPESWEPMGAVAVGHAAEEPRDRPARDAGAFIEVR
What is the function of this protein?
Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
What are the official names of this protein?
Bifunctional F420 biosynthesis protein FbiB.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the CofE family.
Protein: TTC36_DANRE
Sequence: MASAHDRAVLQAIFNPTSPIGDVPGLNQEEELMDDDSAFDPELVKQVKDLELQGVSSAESGDLPAALQHFNQAISVLPQRASAYNNRAQTKRLLGDTKGAVEDLEHAISLSNGKGRSACQALVQRGLLLRLSGHDEEARLDFERAAALGSEFARQQAVILNPYAALCNRMLSEVISKLRNPEVSEMQ
What are the official names of this protein?
Tetratricopeptide repeat protein 36, TPR repeat protein 36.
What is the protein family that this protein belongs to?
Belongs to the TTC36 family.
Protein: METAS_SALPK
Sequence: MPIRVLDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDARESRNTPAEHLNNFYCNFDDICDQNFDGLIVTGAPLGLVEFNDVAYWPQIRQVLEWAKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAHTLAGEYFRDVEAGLNPEVPYNYFPKNDPQNIPRATWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTI1_COPCI
Sequence: MKFTTLATLALGAVSALAAPVTELESRQLFCRDVYVFFARGTGEVGTLGTVVGPGLSAAVKLAVRDSVEFEGIDYPALVSGYLAGGDRGGARTMANKVSQTASRCPNAKIFISGYSQGAQVTHLAARQLSAADQARVTGVVTFGDPYRDDALPGGLQSRRKTYCNVGDLICAGLPTLLAPHFTYGSDTPDAARWIAARV
What is the function of this protein?
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (PubMed:19201950, PubMed:19739639).  Degrades cutin, a macromolecule that forms the structure of the plant cuticle (PubMed:19201950).  Also degrades suberin, a specialized macromolecule found in the cell wall of various plant tissues (PubMed:19201950, PubMed:19739639).
What are the official names of this protein?
Cutinase CUT1, CcCUT1.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
Protein: RL9_PSET1
Sequence: MQVILLDKIANLGGLGDQVVVKSGFARNFLFPQGKAVPATKANIETFDARRAELEAKIADQLVAAQARADKLEALAEVTLVSKAGDEGKLFGSIGTRDIADAISAVGVEVAKSEVRLPLGTIRETGEFDVSIAVHSEVTATIKVIVIAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RECF_KLEP3
Sequence: MSLTRLLIKDFRNIESADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEAGFFTAWSNLKRLVKQRNAALRQVSRYAQLRPWDLELIPLAEQISRWRAEYSAAIVEDMADTCQQFLPEFTLTFSFQRGWEKETDYAEVLERNFERDRMLTYTAHGPHKADFRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRVSGRRCLYLIDDFASELDDARRGLLSSRLKATQSQVFVSAISAEHVMDMSDKNSKMFRVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_XANC5
Sequence: MADRNDQILTPSQLNSLARDLLEGSFPLVWVEAELSSVTRPASGHLYFTLKDARAQIRCAMFKPKSTWLKFQPREGLRVLARGRLTLYEARGDYQLVLDHMEEAGEGALRRAFDELRARLAAEGLFDAERKQALPAHVQRLAVITSPSGAAVRDVLSVLARRFPLLEVDLLPSLVQGDSAAAQITSLLQRADASGRYDVILITRGGGSLEDLWAFNDERLARAIAAAQTPVVSAVGHETDFSLSDFVADVRAPTPSVAAELLVPDQRELVARVRRAQARMTQLQQHALGNAMQRADRLALRLRAQSPQARLQLLHRRQQDAGRQLRARMMQVLERLQARVQQGQAQLQAHNPQRQLAGLQQRLRALHPQAAMQRRLQHDQLQLRSIARSLEAVSPLATVARGYAIVTRPADGSVVRSAAEVVTGERLRAQLADGSIQVRVESGES
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEOC_SALPC
Sequence: MASLIQVRDLLALRGRMEATQISHTLHAPQPMIDAMLNQLEIMGKAVRIPEEADGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: ZWIP2_ARATH
Sequence: MTDPYSNFFTDWFKSNPFHHYPNSSTNPSPHPLPPVTPPSSFFFFPQSGDLRRPPPPPTPPPSPPLREALPLLSLSPANKQQDHHHNHDHLIQEPPSTSMDVDYDHHHQDDHHNLDDDDHDVTVALHIGLPSPSAQEMASLLMMSSSSSSSRTTHHHEDMNHKKDLDHEYSHGAVGGGEDDDEDSVGGDGGCRISRLNKGQYWIPTPSQILIGPTQFSCPVCFKTFNRYNNMQMHMWGHGSQYRKGPESLRGTQPTGMLRLPCYCCAPGCRNNIDHPRAKPLKDFRTLQTHYKRKHGIKPFMCRKCGKAFAVRGDWRTHEKNCGKLWYCICGSDFKHKRSLKDHIKAFGNGHGAYGIDGFDEEDEPASEVEQLDNDHESMQSK
What is the function of this protein?
Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth.  In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712).  May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580).  Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392).
What are the official names of this protein?
Zinc finger protein WIP2, Protein NO TRANSMITTING TRACT, WIP-domain protein 2, AtWIP2.
What is the protein family that this protein belongs to?
Belongs to the WIP C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALB1_ASHGO
Sequence: MPSKNSINRPKQKLNLQHRVQKNAAKRSARERAGLLAPPRSSDQSQSGRAKSIPLDLFRGERVDQGPITTKTLSKKRAKKIERNLRYVEQRKLLVDVQAARESGMDIDVETAVSTKAKTQQTGPLQKVKESIWSALEDVAAQEMIVQTGAGTTLGGQFFP
What is the function of this protein?
Involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.  Accompanies the pre-60S particles to the cytoplasm (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein ALB1.
What is the protein family that this protein belongs to?
Belongs to the ALB1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ERIE_HERER
Sequence: MSAPINGTVEKSYVPGAELWCQEDETAITEPYTYVNSMPGKDVRGRFIEAANHWLHVEPEPLAVICKIVAMLHNASLVIDDIEDNSQLRRGQPVAHKIYGLAQAINSANYVYFLALKEADQLKPYQREGYNSHEIILGALTSVSDFAAQDLLYSVFSDELVNLHRGQGLELVWRDSLRCPTEEQYIDMVNKKTGGLFRLAIKLLTACSSNPSTIDYVPLFNLFGVFFQIRDDLMNLDDNEYEKNKGFAEDLTEGKFSFPVIHGITAQKDNSVLINVLQKRPTTPPLKLHAIHHLRNNTGSFKYTETILNSLETRLRGEIDALGGNPGLLKLVDLLSVRK
What is the function of this protein?
Geranylgeranyl pyrophosphate synthase; part of the gene cluster that mediates the biosynthesis of erinacines, cyathane-xylosides that show unique biological activities, including leishmanicidal activity, stimulating activity for nerve growth-factor synthesis, and agonistic activity toward the kappa opioid receptor (PubMed:31535864).  The geranylgeranyl diphosphate (GGPP) synthase eriE catalyzes the first step in erinacines biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:31535864).  GGPP is then substrate of the diterpene cyclase eriG for the production of cyatha-3,12-diene (PubMed:28371074).  EriG is unable to use geranyl diphosphate (GPP) or farnesyl diphosphate (FPP) as substrates (PubMed:28371074).  The cytochrome P450 monooxygenase eriI then hydroxylates cyatha-3,12-diene at C-14 of the seven-membered ring to produce erinacol, which is further hydroxylated at C-15 by the cytochrome P450 monooxygenase eriC to yield cyathadiol (PubMed:31535864).  The cytochrome P450 monooxygenase eriA then catalyzes C-11 hydroxylation in the presence of the short chain dehydrogenase/reductase (SDR) eriH, which leads to the production of cyathatriol (PubMed:31535864).  The acetyltransferase eriL converts cyathatriol into 11-O-acetyl-cyathatriol (PubMed:31535864).  The SDR eriH catalyzes further oxidation of 11-O-acetyl-cyathatriol into 1-O-acetylcyathin A3 (PubMed:31535864).  Finally, the glycosyl transferase eriJ tranfers xylose from UDP-xylose onto C-14 of 11-O-acetyl-cyathatriol to form eracine Q (PubMed:31535864).  EriJ is also able to convert 11-O-acetyl-cyathatriol to eracine Q2 by using UDP-D-glucose as cosubstrate, but at a lower rate (PubMed:31535864).  In the absence of eriL and eriJ, the SDR eriH is able to convert cyathatriol to cyathin A3; this is likely a switching mechanism in the biosynthesis of cyathins (C-14 ketogroup)and erinacines (C-14 glycosylated group) (PubMed:31535864).  The roles of the SDR eriB, the polyprenyl transferase eriF and the dehydrogenase eriK have still to be identified (Probable).
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase AN1592, GGPP synthase, GGPPSase, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Erinacine biosynthesis cluster protein E, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: PRGR_CANLF
Sequence: MTERTGKDARAPHVAGGAPSPAPAAEPESRRRDGGRLRASQTSDAPRVAAAAAAAAAAASAAPSAPSDRLLFSRRGQGADPGGKAQDAQPRPDVARADPRLEAASGAGADSPGPPRQDRGPLHGAPSTALRPAGPGQGRSSPAWEPRSPRCPSGPEPPEDPRGARSSQGAACPLMSRPEGKAGDGCGTAGAHKGPPRGLSPSRQPLPLCPGAHAWPGAAGKAATQPAALGVEDEGGFAAEGSPGPLLKGKPRPPAGPAAAAGAAPAAPGTAPGGTAPVPKEDSRLPAPKGSLAEQDAPAPGCSPLATTMMDFIHVPILPLGSAFLAARTRQLLEAETYDAGAFAPPRGSPSAPCAPLAAGDFPDCAYPSDAEPKDDAFPLYGDFQPPALKIKEEEEGAEAAARSPRPYLAAGPHSCVFADAPPALPALPPLPPRAPSSRPGEGAPAAAAAAGCSASSASSPGPALECVLYKAEGAPPPQGPFAAAPCRVPGAGACLLPRDGAAAAASAGAAGASPALYQPLGLGALPQLGYQAAVLKEGLPQVYQPYLNYLRPDSDASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRTLDAVALPQPVGIPNESQALSQRISFSPSQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQNQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: PLSY_THIDA
Sequence: MIHLLLVVAAYLLGSLSFAVIVSRAMGLPDPRSFGSGNPGATNVLRTGRKTAAILTLLGDALKGWVAVVAARGLAAQFGLDDDIVLLCALAAFIGHLFPVFFGFQGGKGVATALGILVALDPWLGLACLATWVAMALVFRISSLSALVTAVLAPVYAGLLLGWNDSATTVLVIALLLVYRHKANLLKLVTGQEARIGKRS
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CADH7_HUMAN
Sequence: MKLGKVEFCHFLQLIALFLCFSGMSQAELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNVIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLADMYGTGQESLYS
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
What are the official names of this protein?
Cadherin-7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.