PharMolix/UniProtQA huggingface dataset:
Protein: LPTD_NEIG1
Sequence: MARLFSLKPLVLALGFCFGTHCAADTVAAEEADGRVAEGGAQGASESAQASDLTLGSTCLFCSNESGSPERTEAAVQGSGEASVPEDYTRIVADRMEGQSKVKVRAEGSVIIERDGAVLNTDWADYDQSGDTVTVGDRFALQQDGTLIRGETLTYNLDQQTGEAHNVRMETEQGGRRLQSVSRTAEMLGEGRYKLTETQFNTCSAGDAGWYVKAASVEADRGKGIGVAKHAAFVFGGVPLFYTPWADFPLDGNRKSGLLVPSVSAGSDGVSLSVPYYFNLAPNFDATFAPGIIGERGATFDGQIRYLRPDYSGQTDLTWLPHDKKSGRNNRYQAKWQHRHDISDTLQAGVDFNQVSDSGYYRDFYGGEEIAGNVNLNRRVWLDYGGRAAGGSLNAGLSVQKYQTLANQSGYKDEPYAIMPRLSADWHKNAGRAQIGVSAQFTRFSHDGRQDGSRLVVYPGIKWDFSNSWGYVRPKLGLHATYYSLDSFGGKASRSVGRVLPVVNIDGGTTFERNTRLFGGGVVQTIEPRLFYNYIPAKSQNDLPNFDSSESSFGYGQLFRENLYYGNDRINAANSLSTAVQSRILDGATGEERFRAGIGQKFYFKDDAVMLDGSVGKNPRSRSDWVAFASGGIGGRFTLDSSIHYNQNDKRAEHYAVGAGYRPAPGKVLNARYKYGRNEKIYLQADGSYFYDKLSQLDLSAQWPLTRNLSAVVRYNYGFEAKKPIEMLAGAEYKSSCGCWGAGVYAQRYVTGENTYKNAVFFSLQLKDLSSVGRNPAGRMDVAVPGYIPAHSLSAGRNKRP
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RNH2_CHLAB
Sequence: MNTLAMDAEQLFLSKTIFEEEVFHEGFSLIAGIDEVGRGPLAGPVVAGACILPRGKVFAGVNDSKKLTPKERGKIRDILVNDSEVYYGLGVVSVERIDEINILEATKEAMAAAIANLPIHPDFLLVDGLHLPHKIPCKKIIKGDSKSASIAAASILAKEYRDDLMRELHQLYPDYGFDKHKGYGTAAHLAALKAFGPCDCHRKSFAPVRQVF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_METKA
Sequence: MSHVPLDPETARKVTSSLNYRFEIGGEPLVIAIAQDAENGDVLMTAFANEEAVYRTLTTGYAHYWSTSRREVWKKGEESGHVQRVVEVRVDCDKDAVLYVVEQEGGACHTGYRSCFYRRVTRDGSFEVVMDRVFNPDEVYR
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTI_ECOLC
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUON_RHORT
Sequence: MTFQSLILGPALPEILLAVLGLVLLMVGVFRKTDSTGLVGLLAVYGLLMALAVVGLGAAPETPQLAFGGLFIDDGFARYAKALTLLGAVLTLLLSMVWLKRENEGRFEFPILVLFATIGMMMMISANDLIALYMGLELQSLALYVIAAYQRDNLKSTEAGLKYFVLGALASGLLLYGMSLVYGFAGTTRFDGLAQVAAAEGGISTGLLIGIVFIIAGLAFKVSAVPFHMWAPDVYEGAPTPVTAFFAVAPKIAALTLFARVMMGPFAAYADQWQQVIILISILSMLLGGFAAIVQTNIKRLMAYSSIGHVGYALIGIAAGTTEGVRGVLVYLAIYLFMNVGTFTVILAMRQKGRAVEGINDLAGLSKQHPMMAAAMAVFMFSMAGVPPLAGFFGKFYVFMAAVNSGLFALAVIGVLSSVVAAFYYLRIIKLMYFDEATEPLDALSGTTMKVILIGTAAVVALFFLAPSVVVDGAQAAAEALTFASAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UB2V2_CHICK
Sequence: MAGSTVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPTVRFVTKINMNGINNSNGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
What is the function of this protein?
Has no ubiquitin ligase activity on its own.  The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.  This type of poly-ubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  Plays a role in the control of progress through the cell cycle and differentiation.  Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage (By similarity).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 variant 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: ARRS_LITCT
Sequence: MSGDKKSRSVIYKKTSRDKAVSVYLGKRDYVDHIESVDPVDGVVFVDPDLLKGKKVYVTLTCAFRYGNEDIDVIGLTFRKDLFFARTQVYPPVEDVKCLTKVQERLMKKLGNNAYPFVMAFPDYLPCSVSLQPALSDVNKACGVDFEVKAFSASNLEDRYHKKNSVRLLIRKIQYAPDQPGPTPRAETSWQFFMSDKPLHLTASLAKEVFYHGETITVAVTVTNSSEKTVKKISTSVEQTANVVLYSSDFYTKTVAFDESDEKVSPKSTYKHTFTLLPLLAYNREKREIALDGKLKHEDTNLASSTLLKEGIDRTVMGILVDYKIKVTLTVSGLLGDMTSSEVSTELPFILMHPKPDSGAKESEQEEDFVFEDFARDQLKDELQPEEKEEEEEDEK
What is the function of this protein?
Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
What are the official names of this protein?
S-arrestin, Retinal S-antigen, S-AG, Rod photoreceptor arrestin.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: RS19_ACTP7
Sequence: MPRSLKKGPFLDLHLLKKVEKAVESGDKKPIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSDEMIGHKLGEFAPTRTYRGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: TFE_METBU
Sequence: MTDSNDPVVRGYLLQLIGEEGIEMIENMPEGEVTDEQIAEASGVMLNIVRRTLFIMNENNLAVCRRERDSSSGWLTYLWQLDLSDIESHLVKEKKRITKNLEIRYNFEVDSVFYTCPEGCVRFEFKEASKCEFMCPACGEDMMFEDNSVMVKKLRDRLDALEASS
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: MRH4_PICST
Sequence: MFPLRAQSASLGANSTLFFRAYAVSHRKSGSKIQAWKGLKRGANGANRANGTNSSQPESQSSKAVFQSGKFSQLHQPSKKVYEKSSSGLDSISTFEQLRIFPTVRAAMVAEIKSTYNMKGPRYQSKDELVLKPTPIQVAAIRKINQPRLKNNKNVKEEEVSAGRKSAPSTADLVNEEFKKINSLQKLKVFTLAAETGSGKTWAYLSSLLSKLKEDEFGLYESSEEKYRASRNAQMVKSVVLVPTHDLVEQVYSTLERANSIKFDVEKIGANSRLKEFLQLPEQNGSLNLSILKWGSGEAHKKLFDRCLKGRVDVLVTTPGKLASLSKLQNVNRPYRFLNHVEYCVLDEADTLMDESWIETTMPVIEKFKKLRDLIICSATIPKRFQTTLNRIFPTDDSIINIVTPSLHKLPKQIKVSVIDSELSPYHGSKTRALAQALYAITRDGTEPGLVKRVIVFVNKKESVNSLVDTLVNKFSHRPEDVIGITGEDKPEERSEKLEPFIKPAESIEEDPLNSKIKVLVTSDLMARGVNFVGIKNVIIMDIPHNSVDLVHRIGRTGRMNQSGRVILIVDKKKNKAWLSGLPNAVKRGIQMG
What is the function of this protein?
ATP-binding RNA helicase involved in mitochondrial RNA metabolism.  Required for maintenance of mitochondrial DNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase MRH4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. MRH4 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: THO7B_ARATH
Sequence: MSVKARRISGRLETVVTKVNYAFDPVDDDKIIRNRLLTRTTTTRGEPPLKKLQKKFTSFVLEVDKEEENYNDCGRLAKAFLQELSTFEIPLLKSQAVVEANLREKESFNEVKDETERQIMQAKAEIEDLKKQLEESKIDRQHKEECETIRKLISAQPPRSETEKVIYELNKEIAELEAESTASWRLLELRKKQFALLMHVVDELQNTMEDEQKSLVDEIRSASEDQRNITDAMSVD
What is the function of this protein?
Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export.
What are the official names of this protein?
THO complex subunit 7B, THO complex subunit 7, AtTHO7.
What is the protein family that this protein belongs to?
Belongs to the THOC7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSAJ_VITVI
Sequence: MRDLKTYLSTAPVLSTIWFGSLAGLLIEINRLFPDALTFPFFN
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RBFA_ECOSM
Sequence: MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NORR_SALEP
Sequence: MSFSVEVLAGIAIELQRGIGHQDRFQRLITTLRQVLACDASALLRYESRQFIPLAIDGLAQDVLGRRFTLEGHPRLEAIARAGDVVRFPADSDLPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDAMTPEQFEVFSDEELRLVAALAAGALSNALLIEQLESQNMLPGSSGVFEPIKETHMIGLSPAMTQLKKEIEIVAGSDLNVLIGGETGTGKELVAKAIHQGSPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLFVPPLRERGDDVVLLAGYFCEQCRLRLGLSRVVLSPGARRHLLNYGWPGNVRELEHAIHRAVVLARATRAGDEVVLEEQHFALSEDVLPAPSAESFLALPACRNLRESTENFQREMIRQALAQNNHNWAASARALETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: YEJL_SALPK
Sequence: MPQLSRYSDEHVEQLLSELLSVLEKHKAPTDLSLMVLGNMVTNLINTSVAPAQRQAIANSFARALQSSISEDNAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: GLGB_ECOL5
Sequence: MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPIYRQYHHDKLTFGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGAVHSDEIASHGRQHSLSLTLPPLATIWLVREAE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RZ1A_ARATH
Sequence: MSEDPEYRCFIGGLAWTTSDRGLRDAFEKYGHLVEAKVVLDKFSGRSRGFGFITFDEKKAMDEAIAAMNGMDLDGRTITVDKAQPHQGGAGRDNDGDRGRDRGYDRDRSRPSGGRGGGDCFKCGKPGHFARECPSESSRDGGGRFSSKDDRYSSKDDRYGAKDDRYGAKEDRYGAKDDRYSSKDDRYSSKDDRYGSRDGGGSRYGPDRSGERAGGRSRDGGSRGAPGGERHSRAPYDRPRAGGFH
What is the function of this protein?
Binds RNA and DNA sequences with a preference to single-stranded nucleic acids.  Displays strong affinity to poly(G) and poly(U) sequences.  May be involved in tolerance to cold stress.
What are the official names of this protein?
Glycine-rich RNA-binding protein RZ1A, AtRZ-1a.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RISB_RALSO
Sequence: MDHGFYPTNLEGEGLRIGIVQARFNEPVCEALREACVAELEQLGVAGEDVLLVTVPGALEVPLALQKMAESGQFDALIALGAVIRGETYHFELVSNESGAGITRVCLDFNIAIANGILTTDTDAQAHARTREKGRDCARTAIEMANLTAALDGLQDHGQDDENE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CYB_GEOPI
Sequence: MAIMRKSHPLMKIVNHAFIDLPTPPNISGWWNFGSLLGLCLILQISTGLFLAMHYTSDTLTAFSSVTHICRDVNYGWLIRYMHANGASLFFICLYIHIGRGIYYGSYLYTETWNIGILLLFLTMATAFTGYILPWGQMSFWGATVITNLLSAIPYIGQDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPLGIPSDCGKVPFHPYYSTKDFLGVIMLLMLFLTLVLFFPDKLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSVPNKLGGVVALVMSILVLALLPYLHTSKQRSLMFRPLSQTLFWMLVSDLFLLTWIGGQPVEPPFIIIGQVASIMYFSIILLLMPMAGLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MFD_MYXXA
Sequence: MRLLITLGPSGSTHGHSLHTDAGRRRGGRPFAQVVDELRAGQRVRTQGLKGAARGHVLARLHGALRAPLVCVAVDEEAADALAADLSFFLGGQGSLLAPRVLRLPADEVLPYDEVSPDAAAVTERLGALFHLGQGTRFPALVLSVRALHRKVLPLAVMRALAARVAVGQDFDRDSLARRLVRMGYQNSPLVEDVGTFSVRGDLLDVFSPLYDKPVRLEFFGDTIESIRAFDPQSQRTVDALKEVDLVPAREVLLTDETRPRAESAARAVADRINLPTIKLREQLDALREGLPGFGMEGLLPGFFEDGLSTVFDFLRDWSPEAPVIYLDDPLGQDRAADTLWEELERSHGAAEARQELICPPLEHFLSREDVNQRMQSFRVLEGGGLSLAQTERPPVHFSFGGTQDLREAILAHHGEEGALSPLVERLERWRELRVACVVACGTLSQADRLKRLLMDRNVMVKVHTEPLEDAVALYEPSIRAHLFTGEVSHGFVDGPGGLAVLADEEIFGARARRRPKRSKKLDAFGSGFGDLKEGDLIVHTDFGIGRYAGLTKMEVNGVPGDFLVLEYAGRDKIYLPVGRMRLIQKFSGGDPTQVQLDKLGTTSWEKTKKRVKEQLLKMAAELLQIAAARKAHPGHAFSAPDRYFAQFEADFEFEETPDQAKAIEDVLADMQKPEPMDRLVCGDVGYGKTEVAMRAAFKAALDRKQVAVLVPTTVLAQQHFLSFKKRFADYPVTVEVISGLKKAPEVREILKRAKEGKVDILIGTHKLLGGEVAFKELGLMIVDEEQRFGVKQKESLKKWRSQIDVLTLTATPIPRTLHMSMSGVRDMSIIATPPQDRRAIRTFVMKYEDTVVKEAIEREVARGGQVFFVHNRVESLPSIETQLRALVPQVSIGVAHGQMGEGQLEKVMLAFTEKKYQVLLCTSIIESGIDISSANTMIVNRADQFGLAQLYQLRGRVGRSKERAYAYLLVPSRRAVTKDAQRRLEVLQNFTELGAGFSIASHDLEIRGAGNLLGDKQSGAIAEIGFDMYAQLLEEAVAEMQGQPPKVQIEPDVTLPMPALIPDDYVSDVHQRLVFYKRFSQASHPDEVTDLRAELVDRYGEAPDEVDHLSELTLLKIDMRDLRLRGLEVGTTRLVVTLGADALLDGPKVAGLVQRSKGVYRLTPDMKLIARAPQGASGQDLISEAKKVLRDLSHCALPQA
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_LEGPA
Sequence: MSISKTLPYNAIEQIKSYLLQLQNTICVLLESIDGKTRFHEDSWQRAAGGGGRTRIMTNGNVFEKAGVNFSHVSGEQLPASASAHREELAGRHFSALGVSLVIHPQNPYVPTTHANVRFFVAEKEDSEPVWWFGGGFDLTPYYGFVEDCEHWHQTALNACLPFGETIYPKFKRWCDDYFFIKHRNEARGIGGLFFDDYNEISFDHSFELMRSIGDHFILAYEPIVARRKDIPFGNREKAFQNYRRGRYAEFNLVYDRGTLFGLQSGGRTESILMSLPPTVHWEYNWHPEKGSDEEKLYTDFLPAKDWLKKE
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPNA_ACRCH
Sequence: MGSVPVPVANVPRIDVSPLFGDDKEKKLEVARAIDAASRDTGFFYAVNHGVDLPWLSRETNKFHMSITDEEKWQLAIRAYNKEHESQIRAGYYLPIPGKKAVESFCYLNPSFSPDHPRIKEPTPMHEVNVWPDEAKHPGFRAFAEKYYWDVFGLSSAVLRGYALALGRDEDFFTRHSRRDTTLSSVVLIRYPYLDPYPEPAIKTADDGTKLSFEWHEDVSLITVLYQSDVQNLQVKTPQGWQDIQADDTGFLINCGSYMAHITDDYYPAPIHRVKWVNEERQSLPFFVNLGWEDTIQPWDPATAKDGAKDAAKDKPAISYGEYLQGGLRGLINKNGQT
What is the function of this protein?
Isopenicillin N synthase; part of the gene cluster that mediates the biosynthesis of penicillin, the world's most important antibiotic (PubMed:3903520).  IpnA catalyzes the cyclization of the tripeptide N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine (LLD-ACV or ACV) to form isopenicillin N (IPN) that contains the beta-lactam nucleus (PubMed:3903520, PubMed:3839755, PubMed:8076799, PubMed:8557701, PubMed:9418249, PubMed:9703965, PubMed:9826554, PubMed:9530516, PubMed:9841222).  The penicillin biosynthesis occurs via 3 enzymatic steps, the first corresponding to the production of the tripeptide N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine (LLD-ACV or ACV) by the NRPS pcbAB.  The tripeptide ACV is then cyclized to isopenicillin N (IPN) by the isopenicillin N synthase pcbC that forms the beta-lactam nucleus.  Finally, the alpha-aminoadipyl side chain is exchanged for phenylacetic acid by the isopenicillin N acyltransferase penDE to yield penicillin in the peroxisomal matrix (By similarity).
What are the official names of this protein?
Isopenicillin N synthase, IPNS.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: COBT_RHOCB
Sequence: MLQLNSFAEISTLADRLPVADEAARAAALARQNSLTKPVGSLGRLEELALHWAAWRATERPTITKAQALCFAGNHGVCAQGVNVFPQEVTHLMVKNFEMGGAAINQLCRAAGADLQVISLDLDRPTQDFTQGPAMTEAETVAALNVGAGAVDVTADALIIGEMGIGNSTIAAALAAAIYGGTAKDFVGPGTGSDAAGIARKIAAIDKGLALHGGLGGMETLAALGGREIAAMCGAVLGARAARIPVILDGFISTAAVSTLFKVDPRLLDHCVVGHTSAEPGHQKVLTTMGKRALLQMEMRLGEGTGAALALGVVRAALECHNGMVTYAEAGITA
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: GPDA_RICBR
Sequence: MKRFKNIAVYGGGSFGTSLAAIAARVCENVTLFLRDEEIAKEITDKKTNTKYLGNIKLPSNLQATTNLDKIKDFELIIIAVPSYAFDEAIKLLKTHISNDNILLIATKGFARNPTELFSDRLKTLLSNNPIAFLSGPNLAKDLAKGLPASATIASLDIDLANKISYNLSSEAFVASTINDVITLQVAGALKNIFAIKSGIDMAKEQGENAKATLIVSALKEIAILSKALGGMKNNMDILLEAGVVGDLVLTCYSRSSRNTKFGYEFGISKDKQKFLQEYKELVEGREAIKLVLELIERYDLDMPIVSSLGNVIR
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_STRT2
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYVDQANEYREKLIEAVAETDEDLMMKYLEGEEITNDELKAAIRRATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGINPDTGEEETRPASDEAPFAALAFKIMTDPFVGRLTFIRVYSGILQSGSYVMNTSKGKRERIGRILQMHANSRQEIEQVYAGDIAAAIGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKTKADQDKMAIGLQKLAEEDPTFRVETNPETGETVISGMGELHLDVLVDRLKREHKVEANVGAPQVSYRETFRAATQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLEESMANGVLAGYPMVDIKAKLYDGSYHDVDSSETAFKIAASLALKEAAKTAQPTILEPMMLVTITVPEENLGDVMGHVTARRGRVDGMEAHGNTQIVRAYVPLAEMFGYATTLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNSGEA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.