PharMolix/UniProtQA huggingface dataset:
Protein: H3_ASHGO
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GATC_STAAU
Sequence: MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDSADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RL1_PROMM
Sequence: MPKLSKRITGLLAKVEDRVYQPLEAIQLVKENATAKFDETIEAHVRLGIDPKYTDQQLRTTVALPQGTGQSVRIAVISRGEKLAEAKTAGAELAGDDDLVESIGKGQMDFDLLIATPDMMPKVAKLGRVLGPRGLMPNPKAGTVTTDLAAAIKEFKAGKLEFRADRAGIVHVRFGKASFSADALLENLKTLQETIDRNKPSGAKGRYWKSLYITSTMGPSVEVDVTALQDLEEDA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RL14_NEIG2
Sequence: MIQMQTILDVADNSGARRVMCIKVLGGSKRRYASVGDIIKVAVKDAVPRGRVKKGDVYNAVVVRTAKGVRRPDGALIKFDNNAAVLLNNKLEPLGTRIFGPVTRELRTERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CELA_KOMXY
Sequence: MIKPLKKAVLPVAGLGTRFLPATKCVPKEMLTVVDRPLIQYAIDEAREAGIEEFCLVSSRGKDSLIDYFDISYELEDTLKARKKTSALKALEATRVIPGTMLSVPPAGTAGPWHAIWCAREFIGNDPFAILLPDDVVQSKKSCIGQLVEVYNKTGGNVLAVTEVPREQTGSYGILDVGKDDGKTVEVKGLVEKPDPKDAPSTLSVIGRYVLTADVLKHLAKLEKGAGGEVQLTDAMAKTIGHVPFHGYRYEGKRFDCGSKIASWKPRSPLRWSVRNWLPACVNS
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, Alpha-D-glucosyl-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, Uridine diphosphoglucose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: RL15_AZOSB
Sequence: MRLNTIKPGAGSKSAGKRVGRGIGSGLGKTCGRGHKGQKSRAGGFHKVGFEGGQMPLQRRLPKRGFVSLTRGRCAEVRLSELAQLPVEDVDLLVLKQAGVIAADALSAKVVLSGAISKKVVLRGIAATAGARAAIEAAGGSCGE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: MFSD1_PONAB
Sequence: MEEEDEEARALLAGGPDEADRGAPAAPGALPALCDPSRLVHRLLVLLLMCFLGFGSYFCYDNPAALQTQVKRDMQVNTTKFMLLYAWYSWSNVVLCFFGGFLIDRVFGIRWGTIIFSCFVCIGQVVFALGGIFNAFWLMEFGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYSKIEALLGSAGHTTLGITLMIGGVTCILSLICALALAYLDQRAERILHKEQGKTGEVIKLTDVKDFSLPLWLIFIICVCYYVAVFPFIGLGKVFFTEKFGFSSQAASAINSVVYVISAPMSPVFGLLVDKTGKNIIWVLCAVAATLVSHMMLAFTMWNPWIAMCLLGLSYSLLACALWPMVAFVVPEHQLGTAHGFMQSIQNLGLAIISIIAGMILDSRGYLFLEVFFIACVSLSLLSVVLLYLVNRAQGGNLNYSARQREEIKFSHTE
What is the function of this protein?
Lysosomal transporter which is essential for liver homeostasis.  Required to maintain stability and lysosomal localization of GLMP.
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: Y1808_PYRHO
Sequence: MERNELVNFVEGILKRIGFRTMKLEFRGGCFDLVATRQLLLLFIKALANIDKFSEEQAEDLKKLAKLFKASPLLVGLRSKNAELEDGVVYERFGIYAITPGTLYSMFAEGEPPLIIAERGGFYVRIDGKKLKALREEHGYSITELAGILGISRKSLQRYEKGESVVSLEVALRLEEVFDEPLVKPIDVLRARLKDVTLTSEPDNILEKEVFEKLRKLGMSVVKIKTAPFNAITKEEEDDIELLTGIDERKTGRTLKRAELVSQMAEVVGSDGVFVVKKARMEVVRNVPILPKKLLEEIKDADELLELIRDLKFKS
What are the official names of this protein?
Putative HTH-type transcriptional regulatory protein PH1808.
Protein: DXR_GLOC7
Sequence: MKKISVLGSTGSIGTQTLDIVAQYPDQFQVVGLAAGNNVELLSAQVHQFRPEIVAICNLDHLEVLKESLSSLDYSPIILGGEQGIVEVAGYGDAQSVVTGIVGCAGLLPTIAAIKAGKDIALANKETLIAGGPVVLPLIEKHGVKLLPADSEHSAIFQCLQGVPEKGLRKILLTASGGSFRDLPVEKLSTVTVQDALKHPNWSMGRKITIDSATLMNKGLEVIEAHYLFGLDYDRIEIVIHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYALSWPERIYTDWETLDLVKVGSLTFREPDHHKYPCMKLAYAAGRAGGAMPAVLNAANEQAVALFLEERIGFLDIPRLIETVCDRFTTHNQAHPTLDDIISADQWARGEVIRANEVIEKSDRIVSVR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MTNA_YERPY
Sequence: MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIGLSASLLLALLAERGLSQALLEQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAEALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLATAGIGTAIGVLLRAHQQGNLRQVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGDVANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHCQWAPEDAAVYNPAFDVTPAALISGWVLDSGVITPEQVAAGFFQPHR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: PRSA1_STRP6
Sequence: MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSDFYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQSSLTPETFKRQIRSSKLVEHAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEETAKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGISDVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIANALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSSAEEPTETEAQTQEPAAQ
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 1.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: UF01_MOUSE
Sequence: WIGRW
What are the official names of this protein?
Unknown protein from 2D-PAGE of fibroblasts, P19.
Protein: DAPB_HELPH
Sequence: MKIGVYGASGRIGKLLLEELKGGYKGLALSSVFVRQKCETDFSHFSHSPLVTNDLKAFVRACECVIDFSLPKGLDHLLEALLECPKILVSGTTGLEKETLEKMQQLALRVPLLHAHNMSLGIMMFNQLAFLASLKLKDADIEIVETHHNLKKDAPSGTALSLYETCAKARGYDEKNALTTHREGLRSKESIGIAALRGGDVAGKHTIGFYLEGEYIELSHTATNRSIFAKGALEVALWLKDKAAKKYEINEMFG
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA1_CAMJE
Sequence: MNNIVHKLKTLVLNEAFGGVLLIVCTLLALLVQNGSFSEHYREFLNLKVGFSVGEFELNKPFLLWINDGLISIFFFAIGLELKKEFLHGDFKNPKNIVLPFMAALGGILIPAMLFALVNIGDAYTLKGWAIPTATDTAFALAILMMCGKHIPSSLKIFLLSLAIFDDVGAILIIAIFYTTKLSIAAFVIAGLAILVMLILNLLGITRKSFYFICSVILWISVLKSGVHATLAGIVTAFFIPMQTKNGEAFLEEIYESLKFWIAFIILPLFAFANAGVNLSNIDIGAIFSGVSIGIFLGLFVGKQVGVFLFSYLAIRFKFAALPQGSNLKQLYGVCILTGIGFTMSLFIDGLAYEVSDIFNYADNLAILIASFCSGIWGFIYLKFFTTRS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS10_EXISA
Sequence: MANEKIRIRLKAYDHRVLDQSAEKIVDTAKRSGAKVSGPIPLPTEKSIYTILRAVHKYKDAREQFEMRTHKRLIDIVNPTPKTVDALMRLELPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: BOA16_BOTFB
Sequence: MALEAAKALQQLRTGDLNAFNFVYISGEGATSNPGPFTPLFGRVKGETETGLMKIQSKVANFRLFIVRPSHVDSKGHKAIAPYIPQPTVLLRAANLALGPALRGFLKPYNSPTAPLGEFLVDLATGAQQGRLHGDGVECRGASTIISNVGFRRLMGLS
What is the function of this protein?
Part of the gene cluster B that mediates the biosynthesis of botcinic acid and its botcinin derivatives, acetate-derived polyketides that contribute to virulence when combined with the sesquiterpene botrydial (PubMed:21722295).  Botcinic acid and its derivatives have been shown to induce chlorosis and necrosis during host plant infection, but also have antifungal activities (PubMed:21722295).  Two polyketide synthases, BOA6 and BOA9, are involved in the biosynthesis of botcinins.  BOA6 mediates the formation of the per-methylated tetraketide core by condensation of four units of malonyl-CoA with one unit of acetyl-CoA, which would be methylated in activated methylene groups to yield a bicyclic acid intermediate that could then either be converted to botrylactone derivatives or lose the starter acetate unit through a retro-Claisen type C-C bond cleavage to yield botcinin derivatives (PubMed:23203902).  The second polyketide synthase, BOA9, is probably required for the biosynthesis of the tetraketide side chain of botcinins (Probable).  The methyltransferase (MT) domain within BOA6 is probably responsible for the incorporation of four methyl groups (Probable).  The trans-enoyl reductase BOA5 might take over the enoyl reductase function of BOA6 that misses an ER domain (Probable).  The monooxygenases BOA2, BOA3 and BOA4 might be involved in further hydroxylations at C4, C5 and C8, whereas BOA7, close to BOA9, could potentially be involved in the hydroxylation at C4 in the side chain of botcinins (Probable).
What are the official names of this protein?
Botcinic acid biosynthesis cluster B protein 16.
Protein: RNB_EDWTE
Sequence: MFQDNPLLAQLKQQLHSQTPRVEGVVKGTDKGFGFLEVDAQKSYFIPPPQMKKVMHGDRVRAAVQVDKEREIAEPEELLEPFLTRFVGRIQKKENDERLSIIPDHSLLKDAIGCRPARGLDRAFRQGDWVLAEMRRHPLKGDRSFFAEITAFITDGSDHFAPWWVTLTRHDLARSAPQWQAGTLLEEGLAREDLCALPFVTIDSASTEDMDDALHVRENADGSLCLTIAIADPTAYVSADSPLDAEARHRAFTTYLPGFNIPMLPRDLSDDLCSLREGQRRPVLACEVTLDADGSLRDDIRFFSGWIESKAKLVYDRVSDWLEGRGDWQPPSDDIAAQIRLLHRVANARTQWRQQHALVFRDRPDYRFVLDDHGDVTDIVAEPRRVANRIVEECMITANVCAALVLRERLGFGIYNVHTGFDPALVEQAVSLLNANDVAANAEALLTLDGFCTLRRHLDSLPSTFLDSRIRRFQTFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMVNHRLLKALIAGAPATRPDPAMTLQLAERRRQNRMAERDVGDWLYARFLKDKVNAPTPFNAEIIDISRGGMRVRLLENGAVAFIPASFIHAVRDEMVCSQENGTLQVKGSVVYRQGDTVPVTLSEVRLDTRSLIARPFSA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_RUBXD
Sequence: MARYTGPRGRRDRRAGVMLSSMRKNPLEKKPYPPGEHGRDRQRQTEYGLRLMEKQKARWYYGVSERQFRRAYEEAIRQPGVSGENLLRLMELRMDNVVYRMGFATSRPQARQLVVHGHFLLNGRKHNIPSATLKPGDVITVRDKSRRLQPIQEAVEQVVAVPAWLEADHENFTGRVLHTPSRDEIDAPVEEQLIIEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: NANE_OCEIH
Sequence: MLDQIKNSLIVSCQALPDEPLHSSFIMSKMALAAKQGGAKGIRANTKEDIIQIKEEVNLPVVGIVKRDYKDSEVFITATYKEIDELLESNCEMIAIDATTRNRPQDIKLQDLVDYTKRLNSEVELMADIATLEEAKIAEKLGFDCISTTLHGYTSNTSNHKIYDNDFSFLKNLLSEVKIPIIAEGNILTPEMFKRCIELGAHACVVGGAITRPQEITKRFIG
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: SYFA_LEPBJ
Sequence: MNLSEELDSIYQEAIQKIGSSISEEDLDKNKNDFIGKKGKLTAVLKNVALLSIEEKKTIGQKANELSKKLENFVVETKSSLKKKLFETQAASEFFDSLRPLPNASNGSLHPITQIQYEIEDIFTSMGFSIMDGPEIETDTNNFGALNFTDDHPAREMQDTFYLENGNLLRTHTSAIQVRTLRKLKPPFRIIAPGRVFRYEEVDASHEHTFYQIEGMVVGKDISAANLIDTMQVLLSRIFEKEIKTRLRPGYFPFVEPGFELDINCLVCEGKGCPVCKQSGWLELLPCGLIHPNVLSHAGLDPKEWTGFAFGLGLDRLVMMRYGIHDIRYFQSGNLRFLKQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTHP_BACSU
Sequence: MTNLLEASIEQAGYTSRKKVLTDVFLEVRKGELVGLIGANGAGKSTAIKAILGLSEDFKGHIAWNDCSFAYIPEHPSFYEELTLWEHLDLISTLHGIEESEFAHRAQSLLQTFSLDHVKHELPVTFSKGMQQKLMLIQAFLSKPDMYVIDEPFIGLDPISTKRFVDMLKAEKERGAGILMCTHVLDTAEKICDRFYMIEKGSLFLQGTLKDVQDKTGLEGQSLLDCFYKAVQGDRL
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YthP.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: RL22_MYXXD
Sequence: MESTAHLRFLRMSPRKISTVAELIRGKPVEAALNILKFTKRAAAKPVEKLIKSAVANATDKSKGQVDVDTLYVKTISVDQGPTQRRFMPRAMGRATPIKKKTAHVHVVLAEAKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: METXS_BORPD
Sequence: MTTPVPVPNGGPAPAAVPAAAEPGSVGIVTPQLIRFDTPLPLASGQSLQSYELAVETYGTLNAGRTNAVLVCHALNASHHVAGLAADDPNDVGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPASINPATGHPWGAAFPVLTVEDWVHAQARLADHFGIERFAAVMGGSLGGMQALSWAITCPERVAHCIVIASTPRLSAQNIGFNEVARRAIITDPDFHGGDYYAHNTVPRRGLSVARMIGHITYLSDDDMAEKFGRTQREPAEGGAYRYGYDVEFEVESYLRYQGEKFSRYFDANTYLLITRALDYFDPARGTGGDLARALKPAQADFLLVSFSTDWRFPPERSREIVRALLKNGSPVTYAEIDAPHGHDAFLLDDARYHAVVRGYYERIARELGLDEPAAGAAPAAAEPACAEGCAA
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.  In vitro, has also serine succinyl transferase activity.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENPL_BOVIN
Sequence: MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPAEEEEAAKEDKEESDDEAAVEEEEDEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDMTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKSKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVSDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETTEDTAEDTEQDEEEEMDAGTDEEEQETAEKSTAEKDEL
What is the function of this protein?
Molecular chaperone that functions in the processing and transport of secreted proteins.  When associated with CNPY3, required for proper folding of Toll-like receptors.  Functions in endoplasmic reticulum associated degradation (ERAD).  Has ATPase activity.  May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (By similarity).
What are the official names of this protein?
Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen. Melanosome.
Protein: SODL_VAR67
Sequence: MAVCIIDHDNIRGVIYFEPVHGKDKVLGSVIGLKSGTYNLIIHRYGDISRGCNSIGSPEIFIGNIFVNRYGVAYVYLDTDVNISTIIGKALSISKNDQRLACGVIGISYINEKIIHFLTINENGV
What is the function of this protein?
Superoxide dismutase-like protein with no enzymatic activity.
What are the official names of this protein?
Cu-Zn superoxide dismutase-like protein OPG175.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Accumulates predominantly in cytoplasmic viral factories.
Protein: TGON3_RAT
Sequence: MQFLVALLLLSVAVARALPSASKPNNTSSENNPPIQPSTPLPPGVDISQQVKTNRPTDQRLESDKEGQDKTVARTSASVSSGVESATNLNLDDSKKHPETADAKLKETLQQLLPVDPKQEKSGQKFTKDSGSPTGGDSDNTTGGDSNKTTGVDSDKTSGGDSNKPTGSDNDKPTGGDSNKPTSKVPSNTETPKIDKVQLTEKGQKPTLISKTESGEKLAGDSDFSLKPEKGDKSSEPTEDVETKEIEEGDTEPEEGSPLEEENEKVLGPSSSENQEGTLTDSMKDEKDDHYKDNSGNTSAESSHFFAYLVTAAVLVAVLYIAYHNKRKIIAFALEGKRSKVTRRPKASDYQRLNLKL
What are the official names of this protein?
Trans-Golgi network integral membrane protein TGN38.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass membrane protein.
Protein: ACKA_STAAE
Sequence: MSKLILAINAGSSSLKFQLIRMPEEELVTKGLVERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_ECOSE
Sequence: MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLLGAISGLVFMVLQAWCGVPLAALFSVLVLALMTGGFHLDGLADTCDGVFSARSRDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRHRYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQLLKRTLGGQTGDTLGAAIELGELVFLLALL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPB_SHIB3
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TSPY8_HUMAN
Sequence: MRPEGSLTYWVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYLDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS
What is the function of this protein?
May be involved in sperm differentiation and proliferation.
What are the official names of this protein?
Testis-specific Y-encoded protein 8.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIBBA_ALKCK
Sequence: MFESIDEAITQLKAGGMILVVDDEDRENEGDFLALAETASPETINFMATHGRGLICVPLTEEQAERLQLGQMVSHSTDPHGTAFTVSVDHSHTTTGISAFERAETVRALADANAQPSDFKRPGHVFPLVAKNGGVLRRAGHTEAAVDFAKLCGAKPAGVICEVMNEDGSMARVPELRIIADQHNLPLVTIKDLIAYRRKTEKVVTREVAISLPTEYGDFKAVGYTNTIDGKESVALVKGDVGNGEPVLVRVHSECLTGDVFGSKRCDCGPQLHAALKQIEAEGRGVLLYMKQEGRGIGLINKFRAYKLQEEGYDTVEANERLGFPADLREYGIGAQILRDLGIRDMRLLTNNPRKIAGLEGYDLNIVERVPLQMEAVAENERYLHTKREKLGHMLNL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.