PharMolix/UniProtQA huggingface dataset:
Protein: TSP2_BOVIN
Sequence: MLWPLLLLALWAWPSAQAGDQDEDTAFDLFSISNINRKTIGAKQFRGPDPSVPAYRFVRFDYIPPVSAEHLGRITEAMRRKEGFFLTASMKQDRRSRGTLLALEGPGATHRQFEIVSNGPADTLDLTYWVDGTQHVISLEDVGLADSQWKNVTVQVTGETYSLYVGCDLMDSFALDEPFYEHLQTERSRMYVTKGAARESHFRGLLQNVYLVFENSVEDLLSKKGCQQSQGAETNAISENTETLHLSPMVTMEHVGPSAEKSPEVCEHSCEELGSMIRELSGLHVIVNQLHENLRKVSNDNQFLWELIGGPPKTRNVSACWQDGRFFAENETWVVDSCTKCTCKKFKTVCHQISCPPATCADPWFVEGECCPSCVHDGEEGWSPWAEWTECSATCGSGTQQRGRSCDVTSNTCLGPSIQTRACSLGRCDHRIRQDGGWSHWSPWSSCSVTCGVGNVTRIRLCNSPVPQMGGRSCKGSGRETKACQGPPCPVDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQHGGKDCVGGAKEQQMCNRKSCPIDGCLSNPCFPGAECSSFPDGSWSCGSCPGGFLGNGTHCEDLDECAVVTDVCFATSKAHRCVNTNPGYHCLPCPPRYKGNQPFGVGLEAARTEKQVCEPENPCKDKTHSCHRHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNKNLVCATNATYHCVKDNCPLLPNSGQEDFDKDGIGDACDDDDDNDGVSDEKDNCQLLFNPRQFDYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDEDGHQNNQDNCPHIPNANQADHDRDGQGDACDSDDDNDGIPDDRDNCRLVANPDQEDSDGDRRGDACKDDFDNDSIPDIDDVCPENNAISETDFRNFQMVHLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTEGQVRTLWHDPKNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDV
What is the function of this protein?
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.  Ligand for CD36 mediating antiangiogenic properties (By similarity).
What are the official names of this protein?
Thrombospondin-2, Corticotropin-induced secreted protein, CISP.
What is the protein family that this protein belongs to?
Belongs to the thrombospondin family.
Protein: RSMJ_LEGPH
Sequence: MNRIKAVGYENNELKEKAQLLADQLNLQLDQNADTCLFVTPEKLTLKIRNFSLMFADFSAMTWSKRRGEGKRQGLIRACKPTKGIKILDATAGWGKDAAILATFGADVVMLERHPVMAALLADALSRRNEADIQKMCLSLIASDAISFLHSLQEKDYPDIIYIDPMHPERNKSALVKKEMQVLQQLIGTDHDAMELIELSLSHVKSRVVVKWPQKVKPLLPPDASIDGKTVRFDIYMAQFSSN
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFD_METTM
Sequence: MPFELFGVDAEIPDRKKHIYVKKQGDPEGDIPACNTTTIPGCMTERGCAFAGAKGVITGAIKDALHVIHSPVGCTAYGYGTKRYPTSQEMPDGSMFPIEKFNLKYITGTDLSESDVVFGGMDKLKRCILEAVREFPEANAVYTYATCTTGLIGDDIDAISREVSEEIGKDVVAINAPGFAGPTQSKGHQVANYTLFEDLVGTAEPPRTTEYDVNLIGEYNIDGDLWVLKKYFEEMGINVLSTFTGDCCHDEIKWMHRAKLSLVRCQRSANYIAKLLEERYGVPYMKVDFFGIEYCRKNLMAIGEYFGIPERAERVIEDRMKKIGPEIQYFKDKLRGKRVWVFSGGPKNWHLPRPLEDELGMEVVAVSTMFEHEDGYEKIKKRVREGTVIVDDPNSLELEEIIEKYRPDIILSGIKEKYLAHKLGVPCILIHSYENGPYIGFEGFLNLARDMYAAIYNPVWDLLEFEEDVN
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein alpha chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: HEM1_HELP2
Sequence: MELETHLSKYFTLAFTHKSMSLEMREKLAINSSTTLKEFLQTIKTHCPNIKECMVLSTCNRFEIYASLKHGANTNEQKNALLKILAQNKKMSVSDLEKCVLMNTDESAVHHVFSVCSSLDSLVVGETQITGQMKNAYKFAFEEKFCSKDLTRLLHFAFKCAAKVRNLTGISKQGVSISSVAVKEALNIFEKERIKDKKALVIGLGEMAQLVIKHLLNKQFEVLILGRNAAKFEDFVKELEEPKKVSFQNIENLNAYINEYELLFCATSSPHFIVQNRMLKETIFRRFWFDLAVPRNIEKPVLDNIFLYSVDDLEPMVRENVENRQESRTKAYEIVGLATMEFYQWIQSLEVEPVIKDLRELARISAQKELQKALKKRYVPKEYESNIEKILHNAFNTFLHHPTIALKKNAQKEESDVLVGAIKNLFNLDKSTTCHAQNLNLYKCEYYEE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RL18_CAMJ8
Sequence: MRANVLKRKLTLRIKRKKRIRAKISGCENFPRISVFKSNRTLYIQAIDDVKAVTLAAVDGRKLGVKANKEGAKKIAAEFAKTLKAKKIEQAVFDRNGYVYHGVIAALAESLRENGIRL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL21_HAMD5
Sequence: MYAVFQSGGKQHRVTEGETVRLEKLSNVTGEKINFNQVLMISDGETIKVGAPLINGGLVQAEVMAHGRADKIKIIKFRRRKHYRKQQGHRQWFTDVKIIGIIS
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SYY_SALSV
Sequence: MASSNLIKQLQERGLVAQVTDEDALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVAKIRKQVAPFLDFDCGENSAIAANNYDWFGSMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDQGISFTEFSYNLLQGYDFACLNKLHGVALQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMDIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLVAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDAELQPSRGQARKTIASNAVTINGEKQSDPEYIFNDEDRLFGRYTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_EMENI
Sequence: MGDSPKCLRDSLREALRRREDKLCRRKLTILPSSSVDFSSNDFLSLSTSPAYRARFLDILQQAPPLHPFASGGSRLLDGNSAYAEELENFIAAFHNAPSGLLFNSGYDANVGVFSSIPQPGDLIVYDELIHASAHEGMRLSRAGKRIKFPHSSPDGLRAVLQAEITADPRLLQGRRNVFIAFESVYSMDGDVAPIREFVEIVDQLLPYGNGYFLVDEAHATGVFGPRGSGVVQELGLEDRMFVRVHTFGKALASHGAIVLCCADTRDYLINYARSLIYTTALGFPFLASIRAAYELLVEGKTEQLQHKLGQLIAHFRTGLDNLNHKDSSTFEVEHFTNSPIFSLRSSVPRVLASVCQEQGYTVRAIMPPTVPAGKERVRVCLHAGNTVEEVDGLLETIATWLQRMEKQKARL
What is the function of this protein?
8-amino-7-oxononanoate synthase; part of the cluster involved in the biosynthesis of biotin (also known as vitamin B8 or vitamin H), a water-soluble vitamin that functions as a prosthetic group of many carboxylases, such as acetyl-CoA carboxylase and pyruvate carboxylase (PubMed:20713166).  Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON) (By similarity).
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: DPOE2_ARATH
Sequence: MSGRRCDRRLNVQKVSAADELETKLGFGLFSQGETRLGWLLTFASSSWEDADTGKTFSCVDLFFVTQDGSSFKTKYKFRPYLYAATKDNMELEVEAYLRRRYERQVADIQIVHKEDLYLKNHLSGLQKKYLKVSFDTVQQLVEVKRDLLHIVERNLAKFNALEAYESILSGKREQRPQDCLDSVVDLREYDVPYHVRFAIDNDVRSGQWYNVSISSTDVILEKRTDLLQRAEVRVCAFDIETVKLPLKFPDAEYDQIMMISYMVDGQGFLITNRECVGKDIEDLEYTPKPEFEGYFKVTNVTNEVELLRKWFSHMQELKPGIYVTYNGDFFDWPFIERRASHHGIKMNEELGFRCDQNQGECRAKFVCHLDCFSWVKRDSYLPQGSQGLKAVTKVKLGYDPLEVNPEDMVRFAMEKPQTMASYSVSDAVATYYLYMTYVHPFVFSLATIIPMVPDEVLRKGSGTLCEMLLMVEAYKANVVCPNKNQADPEKFYQGKLLESETYIGGHVECLQSGVFRSDIPTSFKLDASAYQQLIDNLGRDLEYAITVEGKMRMDSVSNFDEVKEVIREKLEKLRDDPIREEGPLIYHLDVAAMYPNIILTNRLQPPSIVTDEVCTACDFNGPEKTCLRKLEWVWRGVTFKGNKSEYYHLKKQIESESVDAGANMQSSKPFLDLPKVEQQSKLKERLKKYCQKAYSRVLDKPITEVREAGICMRENPFYVDTVRSFRDRRYEYKTLNKVWKGKLSEAKASGNLIKIQEAHDMVVVYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGVVTYTGAKIIQNARLLIERIGKPLELDTDGIWCALPGSFPENFTFKTIDMKKFTISYPCVILNVDVAKNNSNDQYQTLVDPVRKTYNSRSECSIEFEVDGPYKAMIIPASKEEGILIKKRYAVFNHDGTIAELKGFEMKRRGELKLIKVFQAELFDKFLHGSTLEECYSAVAAVANRWLDLLEGQGKDIADSELLDYISESSTMSKSLADYGQQKSCAVTTAKRLADFLGDTMVKDKGLRCQYIVAREPEGTPVSERAVPVAIFQTDDPEKKFYLQKWCKISSYTGIRSIIDWMYYKQRLHSAIQKVITIPAAMQKVANPVLRVRHPYWLEKKVCDKFRQGKIVDMFSSANKDHSTTQDNVVADIEEFCKENRPSVKGPKPVARSFEVDRNHSEGKQQESWDPEFHDISLQNVDKNVDYQGWLELEKRKWKMTLTNKKKRRYSSSLFGFDLEQNINKKVCKGRVGVGSYFRRPEEALTSSYLQIIQLVQSPQSGQFFAWVVVEGLMLKIPLTIPRVFYINSKASIAGNFTGKCINKILPHGKPCYNLMEVNIQEDQFIKESKKLAALLADPEIEGIYETKMPLEFSAICQIGCVCKIEDTAKHRNTQDGWKLGELHRITTTECRYLENSIPLVYLYHSTSTGRAVYVLYCHASKLMSVVVVNPYGDKELLSSALERQFRDRCQELSPEPFSWDGILFQVEYVDHPEAATKFLQKALCEYREENCGATVAVIECPDFNTTKEGVKALEDFPCVRIPFNDDDNSYQPVSWQRPAAKIAVLRCASAIQWLDRRIAQSRYAHVPLGNFGRDWLTFTVDIFLSRALRDQQQVLWVSDNGVPDLGDINNEETFLADETSLLFPGAYRKVSVELKVHRLAVNALLKSDLVSEMEGGGFLGVNSRGSSLNDNGSFDENNGCAQAFRVLKQLIKRLLHDACNSGNIYADSILQHLSWWLRSPSSKLHDPALHLMLHKVMQKVFALLLTDLRRLGAIIIYADFSKVIIDTGKFDLSAAKTYCESLLTVMGSRDIFKLILLEPVHYWHSLLFMDQHNYAGIRATGDEISGNEVTIEPKWSVARHLPEYIQKDFIIIVATFIFGPWKFALEKKRGSAESLEAEMVEYLKEQIGTRFISMIVEKIGNIRSHIKDINVSDASWASGQAPKGDYTFEFIQIITAVLALDQNVQQDVLVMRKILLKYIKVKECAAEAEFIDPGPSFILPNVACSNCGAYRDLDFCRDSALLTEKEWSCADPQCVKIYDKEQIESSIIQMVRQRERMYQLQDLVCNRCNQVKAAHLTEQCECSGSFRCKESGSDFHKRIEIFLDIAKRQKFRLLEECISWILFATSC
What is the function of this protein?
DNA polymerase II, which participates in chromosomal DNA replication (By similarity).  Involved in the determination of cell fate during plant embryogenesis.  Contributes to the flowering time repression.
What are the official names of this protein?
DNA polymerase epsilon catalytic subunit B, DNA polymerase 2 b, AtPOL2b, DNA polymerase II subunit b, Protein TILTED 2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPIB_NEUCR
Sequence: MFSLRRLLLAATLFLGAMLLFAQSAEAAKGPKITHKVYFDIEQGDKPLGRIVMGLYGKTVPKTAENFRALATGEKGFGYEGSTFHRVIKQFMIQGGDFTKGDGTGGKSIYGDKFPDENFKLKHSKKGLLSMANAGKDTNGSQFFITTVITSWLDGKHVVFGEVLEGYDVVEKIENTKTGPRDAPAEPIKIAKSGELEVPPEGLEGQSEWASPAYANEDEKPAAPVPVTDAKPPAHDSIPAATADDDDTGAPLFAKVLFFGVLVLGLVLYIRLRRAPKGTYGKGME
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B, PPIase B, Rotamase B.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
What are the subcellular locations of this protein?
[Isoform Long]: Membrane; Single- pass membrane protein. SUBCELLULAR LOCATION: [Isoform Short]: Endoplasmic reticulum lumen.
Protein: Y1828_MYCTU
Sequence: MSAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEGLVTPRRASSGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQPDGELPPFGSPYVLPRLVPVAGDSAGGVGSDTASVSLTGIRLSREDLLERSEVADELLTALLKAGVITTGPGGFFDEHAVVILQCARALAEYGVEPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSAVRDVLHR
What is the function of this protein?
Transcriptional regulator that binds to its own promoter and thus may play a role in the regulation of the cotranscribed genes Rv1827 and Rv1828.  Can also bind several promoter regions of genes that are essential, including ftsZ.  Binds to the imperfect everted repeat sequence CTCAA through its winged-HTH motif.
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator Rv1828.
Protein: HIS1_SPHAL
Sequence: MCATLMPEPIIFAIPKGRILDEALPLLARVGIEPAADFFDKKSRALVFGTNQSHISLIRVRAFDVATFVAHGAAQLGIVGSDVVDEFDYSELYAPVDLGIGHCRLSLAGPEGGAPPGLGESHIRVATKYPATTRRWFAAQGIQAECIKLNGAMEIAPKLGLASHIVDLVSTGRTLVENALAEQKIISEVSARLIVNRAAFKLNSAEVPALVERFRQAVGDAAA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RX1_DANRE
Sequence: MHLSLDTMNMVDDSCLSPSNFHDMVKAGGAVVGTRVHSIDVILGFNKDQDSLLNPGDNAVAHKVGGESLGEPGKLDQRVQPYGHLPPLRDGSEQPTFHDADMFSNKCDGDLGDLRKAIESDSKSPDSADGEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWRRQEKIDASTMKLHDSPMLSFNRPSMHPTVGPMNNSLPLDPWLPSPLSSATPVHSIPGFMGPTQGLQTGYPGHSFLSPPQPMAQSMQPMAPPPYQCPPPFTDKYPLEDVDQRSSSIAALRMKAKEHIQSMDKTWQPMC
What is the function of this protein?
Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.
What are the official names of this protein?
Retinal homeobox protein Rx1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: URH2_ORYSJ
Sequence: MDLQEAAMEARNGHRIPPTEEKVIIDTDPGIDDSVAIMMAFEAPGVKVVGLTTIFGNCTTSHATRNALILCDRAGRPEVPVAEGSAEPLKGGKPHVADFVHGSDGLGNTSFPDPTTTNKVEQSAAEFLVDKVSESPGEISVLALGPLTNIALAMKKDSSFASKVKRIVVLGGAFFAAGNATPSAEANIHSDPEAADIVFTSGADIYVVGLNITTQVYFTDKDMLELRNSKGKHAQFLCDICKFYRDWHVHSYGVDALFLHDPVSFTALVHPEYFTFKKGVVRVETQGICKGHTSMDMGLKKWNSDNPWTGYSPISVAWTVDVPKVLAYAKELLFNAQ
What is the function of this protein?
Involved in pyrimidine breakdown.
What are the official names of this protein?
Probable uridine nucleosidase 2, Uridine ribohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the IUNH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THI4_ASPFU
Sequence: MSPPAAIFEPAVAPSPSLKAKVLVPETVPASGTSQTHLLDHFGGKWDDFKFAPIRESQVSRAMTRRYFQDLDKYAESDIVIVGAGSCGLSTAYVLAKARPDLKIAIIEASVSPGGGAWLGGQLFSAMVLRRPAEVFLNEIGVPFEEDPANPNFVVVKHASLFTSTLMSKVLSFPNVKLFNATAVEDLVTRPSASGDAKDTQIAGVVVNWTLVTLHHDDHSCMDPNTINAPVVISTTGHDGPFGAFCAKRLVSMNTVDKLGGMRGLDMNSAEDAIVKNTREVAKGLIIGGMELSEIDGFNRMGPTFGAMVLSGVKAAEEALKVFDQRQRECAE
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MURD_BORBR
Sequence: MNTTETSRAAAPLVLILGLGETGVAAARWCARQGSPLRVADTRAQPGGLAALQAALADATVEYRLGCGEQFPPDLLDGVAQIVLSPGLVPHESPTRELLEQARERNVEVVGEIELFARALAGLAESREYRPRVLAITGTNGKTTVTALTRQLIEAGGMSARAAGNISPAALAALIDALDQDDLPQVWVLELSSFQLETTRTLAPDAAVVLNVTQDHLDWHGDMQAYAQAKARILKPARLAIVNRDDPLTVAMVESLQALNVRSFGRDVPALVGDMGLELGQGVAWLTACESNDFDEPAPAPRRKKDAPPPTRAGGRMSRLMPVDALRIRGVHNALNALAAMQLARSLDLGWGPMLRTLRDYAGEPHRAELVRSIGDVDYINDSKGTNVGATVAALEGLGQQVVLIAGGQGKGQDFSPLVPVVRRHARAVVLIGVDGAAIGKVLEPTGVPCVAAADMREAVRRAAELAQPGDAVLLSPACASFDMFRNYPHRGEVFAAEVQELALDRGEVA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAGG_BACSU
Sequence: MNDLLRILREQITSFPLILRLAAYETKSKYQMNYLGVLWQFLNPLIQMLAYWFVFGMGIRKGGPVTTGAGEVPFIIWMLAGLIPWFFISPTILDGSNSVFKRINMVAKMNFPISSLPSVAIASNLFSYMIMMVIYIIVLLVNGVFPSVHWLQYIYYFICMIAFMFSFSLFNSTISVLIRDYQFLLQAVTRLLFFLLPIFWDVNAKLGQSHPELVPVLKLNPLFYIIEGFRNSFLDGAWFFHDMKYTLYFWLFTFLLLLVGSILHMKFRDKFVDFL
What is the function of this protein?
Part of the ABC transporter complex TagGH (TC 3. A. 1. 34. 1) involved in exporting the two types of intracellularly synthesized teichoic acids.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Teichoic acid translocation permease protein TagG.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOB_STRP4
Sequence: MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHGLKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVRNTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVGRYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKIVYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYFLNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIVWLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQYNGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIADGPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDTKLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQEVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: NSP1_ROTHJ
Sequence: MATFKDACYHYKRINKLNNNSLKLGVNDTWRPSPPTKYKGWCLDCCQHTDLTYCSGCTMYHVCQWCSQYGRCFLDNEPHLLRMRTFKNEVTKDDLKNLIDMYETLFPMNHKIVCRFINTARQHKCRNECMTQWYNHLLMPITLQSLSIELDGDVYYVFGYYDNMNNINQTPFSFINLVDIYDKLLLDDVNFTRMSFLPASLQQEYALRYFSKSRFINEQRKCVNDSHFSINVLENLHNPSFKIQITRNCSELSFDWNEACKLVKNVSAYFDMLKTSHIEFYSVSTRCRIFTQCKLKMASKLIKPNYITSNHKTLATEVHNCKWCSVNNSYTVWNDFRIKKIYDNIFNFLRALVKSNVNIGHCSSQEKIYEYVKDVLNVCDDERWKTSIMEIFNCLEPVELDDVKYVLFNHEINWDVINVLVHSIGKVPQILTLENVITIMQSIIYEWFDIRYMRNTPMVTFTIDKLRRLYTGLKTVEYDSGISDIE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.  Recognizes the host NF-kappa-B regulator BTRC through the presence of a DSGXS motif in the C-terminal substrate recognition domain.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: TXF18_LYCSI
Sequence: MNSKIFAVLLLLGLLSCVLSDQYCPKSSITACKKMNTRNDCCKDDDCTGGSWCCATPCGNFCKYPTDRPGGKRAAGGKSCKTGYVYY
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
U15-lycotoxin-Ls1h, Toxin-like structure LSTX-N18.
What is the protein family that this protein belongs to?
Belongs to the venom protein 11 family. 01 (wap-1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LYTR_STAAW
Sequence: MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
What is the function of this protein?
Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis, programmed cell death, biofilm formation and cell wall metabolism.  Participates also in sensing and responding to host defense cationic antimicrobial peptides (HDPs).  Upon phosphorylation by LytS, functions as a transcription regulator by direct binding to promoter regions of target genes including lrgA and lrgB, to positively regulate their expression.
What are the official names of this protein?
Transcriptional regulatory protein LytR, Sensory transduction protein LytR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_PSEAB
Sequence: MSAITITEAAQAYLAELLEKQSTPGIGIRIFITQPGTQYAETCIAYCKPGEEKVEDTAIALKDFTAWIDAVSEPFLEDAVVDYATDRMGGQLTIKAPNAKVPMVNEDSPITERINYYLQTEINPGLASHGGQVSLVDVVEDNIAVLRFGGGCQGCGMVDMTLKDGVEKTLIERIPELKGVRDVTDHSNKENAYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: DEFI_APICA
Sequence: MKIYFIVGLLFMAMVAIMAAPVEDEFEPLEHFENEERADRHRRVTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKGVCICRKTSFKDLWDKRFG
What is the function of this protein?
Found in royal jelly and in hemolymph, potent antibacterial protein against Gram-positive bacteria at low concentration.
What are the official names of this protein?
Defensin-1.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KUP3_RHOPA
Sequence: MVLAGVAQRPWIKSCDRAFYGSMALSAATTEAPEQTGFWALTLGGIGVVFGDIGTSPLYAFREAVAGAAGGAPASRVLVLGVLSLILWALLIVVTAKYVLLLLRADNNGEGGTLSLMALGRRALGRRSLFLLVLGVIGASMFIGDSMITPAISVLSAIEGLKIAAPALEHYVVPLTVLVLVLLFGVQSHGTAIVARFFGPVMLVWFATLAAMGAMHIMDDPSVLAAINPWYAAQFLASHGTIGLVTLGAVFLAVTGGEALYADLGHFGRRPIQTAWLGFVLPALLINYFGQGALVLSNPAALENPFYKMVPEALVLPLTLMATAATVIASQAVITGAFSLISQAVQLGLLPRFEVRYTSETNAGQIYLPRVNALLLIGVLLLVLLFQTSSRLASAYGIAVSTTMVVDGIMGFVVIWKLWRWSWPAAALVILPLVLVDAMFFSANLLKLLDGAWVPLLFGLAMAVVIWTWRRGVALLMIKSRRAEVPLDDLIGSLEKHPPHIVKGTAVFLTADAEFVPPALLHNLKHNKVLHEHNVILTIETMHTPRVEAADRIRLVKVSEKFSKVALRFGFMETPNVPKALVLARKLGWEFDIMSTSFFVSRRSLKPAAQSEMWRWQTKLFVALAKSANDATDYFQIPTGRVVEVGAQVTI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 3.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.