PharMolix/UniProtQA huggingface dataset:
Protein: METAA_BACC7
Sequence: MPIIIDKDLPARKVLQEENIFVMTKERAETQDIRALKIAILNLMPTKQETEAQLLRLIGNTPLQLDVHLLHMESHLSRNVAQEHLTSFYKTFRDIENEKFDGLIITGAPVETLSFEEVDYWEELKRIMEYSKTNVTSTLHICWGAQAGLYHHYGVPKYPLKEKIFGVFEHEVREQHVKLLQGFDELFFAPHSRHTEVRESDIREVKELTLLANSEEAGVHLVIGQEGRQVFALGHSEYSCDTLKQEYERDRQKGLNIDVPKNYFKHNNPNEKPLVRWRSHGNLLFSNWLNYYVYQETPYVL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS18_ARATH
Sequence: MDATRTFFGLPNVHNVPLCLTSNLSLFPQRLLQKHTLPLKPAKKHHLVCVRSTKSSDDLEGSRPSTYFSPSLWGDHFLSVSLDRGEFDELEREIETMKPLVKDMLMSSQSSDKEKIRLIHLLVSLGSSYHFDKEIQDILKHSFTKLDDIIVGEDDLETISIMFEVFRLYGHKMSCDAFDRFRGEDGRFKESLAKDVRGMLQLFEVAHLGTPSEDIMDEASSFAQNHLDSWIGGNVSGATPHLLKHIQNSLYIPRYCNIEVLVAREYISYYEQEEGHNKILLKFAKLNFNFCQFHYIQELKTLTKWWKDLDLASKLPYIRDRLVESHLGGLGPYFEPHYSLGRIIVAKIIMTMVVVDDTYDAHATVPEVAVLTECLQRLNIGADDKLPDYLRTVLESVFEVMGEIEQEMRPKGRSYGVKQVLERFKNVAKADKQLTEWARTGDVPSFDEYMKVGLVTAGMDGYAGYCFIGMEDVSEKEAFEWLSSNPLIIQALNVMFRLANDVGTYETEINRGEVANGLNCYMKQYGVTKEEASQELRKIYSNNKKVVMEEFMNSHDHVPRQVLLRCLNFARLFDVMYTEGDGYSEPKGKIEHFMTSLYVHPIPLS
What are the official names of this protein?
Terpenoid synthase 18, AtTPS18.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TP4A1_MOUSE
Sequence: MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
What is the function of this protein?
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis.  May play a role in the development and maintenance of differentiating epithelial tissues (By similarity).
What are the official names of this protein?
Protein tyrosine phosphatase type IVA 1, Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1, PRL-1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Early endosome. Endoplasmic reticulum. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Nucleus. Note=And mitotic spindle.
Protein: CST12_MOUSE
Sequence: MLWKSVLSVALIVLGIHDCSFKFLEIDKNEEEFAISVEHVVFHFNENQDDDFAYKFLRVRRSLRQKYTLKYLVDLEMGRTLCGKYDEDIDNCPLQEGPGERKVRCTYIVETEAWVTKFTILNSTCVQT
What is the function of this protein?
May play a specialized role in spermatogenesis.
What are the official names of this protein?
Cystatin-12, Cystatin TE-1.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TOIP2_RAT
Sequence: MSQTLKSQDTNMSDSGYRDPVEDSQNVLGNDPSVNSQAQDPIVTPSNTVEAQTLHPTSDLKEDHHEIGAKGQEHADTGDRAESSEEPALEKPPLDKAELERSPSSQDTEQRHHPYSEHVGGDTLVLDPNYSQSDLGGRADAHLESSSAAPTEGAGEGGEAGAHLESSCAALPVGADEGGRANAHLESSSAAPTEGAGEGGEADVHLESSSAVPPEEAHLESSSAAPSEGAGEGGEADAHLESSSAAPSEGAGEGGETAQNLLAVDSTDAQSPCHSSAGPGSQDSLRRRLPVTEAERHEEETQLVTEKEEVAQETLRKTEKKSLWTYGSMFLGCLIVAVVLSSVNSYYSSPAQQVPQNPALEAFLAQFSQLREKFPGQSAFLWQRGRKFLQKHLNASNPSEPATVIFTAAREGKETLKCLSYHVANAYTSSQKVTAVSIDGAERALQDSDTVKLLVDLELSYGFENGHKAAVVHHFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEETLEASVSPRETEEKVRDLLWAKFTDSGTPSSFSHMDSDKLSGLWSRISHLVLPVQPVKNIEERGCLL
What is the function of this protein?
Required for endoplasmic reticulum integrity.  Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope as well as induces TOR1A, TOR1B and TOR3A ATPase activity (By similarity).
What are the official names of this protein?
Torsin-1A-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the TOR1AIP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus envelope.
Protein: SYL_YERPA
Sequence: MQEQYRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDREIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEKLSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMATMEKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKPVILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILPEDVVMDGISSPIKADPEWAKTTVNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHAIMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVERDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEMTLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTDDVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQALGGEGDIDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO2_LACJO
Sequence: MTVYVEKVRALEIFDSRGNPTVEVHAYLSDGTVAKAEVPSGASTGEKEAVELRDGGNRLQGKGVTQAVTNVNGPINDALKGLSPYNQAEIDRTMIKLDGTLNKAKLGANAILGTSMAIARAAARSKDEPLYRYLGGCELEMPQTFHNVINGGKHADNGIDIQEFMITPVAKNSFRDGFEKIVNTYHALKAVIEEAGFETGLGDEGGFAPNLNSSEEALKMLRKAIIKAGYKPRKDIAIAFDAAASSFYNTEDGKYHFEGHIWNGEEMLQYYDKLLKEFPEIISCEDPFDENDWENFEKFTAKFGSTHQVVADDNVCTNPKLVRKAIKDKLCNSILIKLNQIGTITETLETIRLARKNNMTTMVSHRSGETGDTFIADFTVATNAGQLKSGAPARSERVEKYNRLLEIENQIGVENERLNHFPNNVDFD
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 2, 2-phospho-D-glycerate hydro-lyase 2, 2-phosphoglycerate dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GPMA_CORGB
Sequence: MTNGKLILLRHGQSEWNASNQFTGWVDVNLTEQGEAEAKRGGELLVEAGVLPGVVYTSLLRRAIRTANIALNAADRHWIPVIRDWRLNERHYGALQGLDKAATKEKYGDDQFMEWRRSYDTPPPELADDAEYSQANDPRYADLDVVPRTECLKDVVVRFVPYFEEEILPRAKKGETVLIAAHGNSLRALVKHLDGISDADIAELNIPTGIPLVYEIAEDGSVVNPGGTYLDPEAAAAGAAAVANQGNK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: MRAZ_AGRRK
Sequence: MNRFLSNATNRIDAKGRVSVPAAFRSVLTERNIQELYCFQDFVFPAISVGGLDLLDRFERQIAADDPFSPAANQMSLLIHGGGVFVRLDAEGRLMVTDFIRDFTGITNEVTFVGRADHFQLWQPEAFQALQAQAREERKLAGRRSE
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: OSTC1_SOLSE
Sequence: MKTLSVLVLCSLAVLCLTSDASFSSQPAVDTPAQEGLFVEQEQASSVVRQAPKELSLSQLESLREVCELNLACEDMMDTSGIIAAYTTYYGPIPF
What is the function of this protein?
Binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin 1, SseOC1, Bone Gla protein, BGL, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: YTGA_ECOLI
Sequence: MSIIILATISTTQENK
What are the official names of this protein?
Protein YtgA.
Protein: IF2_LIMF3
Sequence: MAKERIYELAKELKMPSKDLVNLAKKEGMDVKTHMSSVTSDEANKLRSMAKGAGKPAAVKPAPKVQEHQSAPAKKEASRPANQGSQNNQNRNNRGNRNNNGNNNRHNSNNGSANANGNGGNQKRNQKRNQNNNNQGGQAANRNNNNGQGQGAHWFKKGKKNNKKKNRNKGNQRLRDTAPKAPTQRKDRPLPDVLEYTNGMNAQDLGKILHRSPAEIIKKLFMLGVMVNQNQSLDADTIEILAADYGIGAKEKVQVDVADLDHFFDERINNDANLADRPPVVTVMGHVDHGKTTLLDKIRHSHVTEGEAGGITQAIGAYQVKYNDKLITFLDTPGHAAFTEMRARGANITDITVLVVAADDGVMPQTIEAINHAKAAGTPIIVVVNKIDKPGANPDHVTEQLTEYGLIPEDWGGDTIYVKVSAKFGKNIDELLDMILLQAEVMELKANPGQNAAGAVVEARLDQGKGSVATLLVQQGTLHVGDPIVVGDTFGRVRTMTNENGRRIKDATPSTPVEITGLNGVPEAGDHFVVFDDEKTARAAGEERAKRAEDEKRRRTSHVTLDNLFDTMKKGEMKSLPIIIKADVQGSVEALAQSLQKIQVDGVRVDIIHKAVGAISESDVTLAEASNAIIIGFNVRPTPLAKSEAETNNIDIRLHRVIYNAIEEVEDAMKGMLEPVYEEEVLGQVEVRQLYKASKIGTIAGGMVVSGKITRDAKVRLIRDGVVIYEGELGSLKRFKDDAKEVKMGFECGLTIKNFNDVKENDVIEAYHMKEVPVK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAL_SCHPO
Sequence: MTKNIQVLFVCLGNICRSPMAEAVFRNEVEKAGLEARFDTIDSCGTGAWHVGNRPDPRTLEVLKKNGIHTKHLARKLSTSDFKNFDYIFAMDSSNLRNINRVKPQGSRAKVMLFGEYASPGVSKIVDDPYYGGSDGFGDCYIQLVDFSQNFLKSIA
What is the function of this protein?
May contribute to dephosphorylation of 'Tyr-15' of cdc2.
What are the official names of this protein?
Low molecular weight phosphotyrosine protein phosphatase, Low molecular weight cytosolic acid phosphatase, PTPase, Small tyrosine phosphatase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF3_GRVMC
Sequence: MDTTPASRGQWPVGIMSSVINVFASGKSCNSGGAPRSSVRRGHRAGAARDKSRGFDAPPRRPKGGVHPATTSKDPNKDIRGPPAPTPHKKYRGPAIPGEGRSGVHTTRPRRRAGRSGGMDPRQLVAQPQQRWAKTEIPTERRAEIDGLLPSLLNTLDGQIQGDAALLRYCVGAIKRELRRRWESVQPAHHVAASSGKPSPQLFNEAAQNAEDLSGDGKGCAGQSVQQEVLHSGSGVPPVCADCGKPAANKW
What is the function of this protein?
Protects and provides long-distance movement to viral RNA.  Self associates and binds viral RNA and fibrillarin to form filamentous ribonucleoproteins (RNPs) protected from RNase.  ORF3 protein actually fulfills functions that are usually provided by capsid protein, which is absent from umbraviruses' genome.
What are the official names of this protein?
Long-distance movement protein, ORF3 protein.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus, host nucleolus. Note=Passes through Cajal bodies to the nucleolus and exits back into the cytoplasm (PubMed:17410203). This journey is absolutely required for the formation of viral RNPs particles (PubMed:17410203). In the cytoplasm, forms in large cytoplasmic inclusions (PubMed:12584328).
Protein: AROC_MYCSJ
Sequence: MLRWTTAGESHGRALVAVLEGMVAGVSLTTEDIGAQLRRRRLGYGRGARMKFEQDEITMLGGVRHGVTLGGPIAIQIGNTEWPKWETVMAADPVDPAELAEIARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTVARAFLRQALGVEVVSHVISIGASTPYDGPPPQPADLTAIDDSPVRAFDEAAEKSMIAEIEAAKRDGDTLGGVVEVVVSGLPVGLGSFTSGDNRLDSQLAAAVMGIQAIKGVEIGDGFETARRRGSVAHDEIYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDMTTGDEAVAIHQRSDVCAVPAAGVVVETMVALVLARAALQKFGGDSLTETRTNVESYLRAVAAREPATAQRAQASG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: D42E1_MACFA
Sequence: MDPKRSQKETVLITGGGGYFGFRLGCALNQKGVHVILFDISSPAETIPEGIKFIQGDICHLSDIEKAFQDADITCVFHIASYGMSGREQLNRNLIEEVNIGGTDNILQACQRRRVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEKKVLEANGTPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGSRDSECFIWDGLLVFLLIIAVLIWLPSSVILSL
What are the official names of this protein?
Short-chain dehydrogenase/reductase family 42E member 1.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LCV1_ARATH
Sequence: MANRERDRELLIPVADFGDKDDGSSSKPSSSSSASSSHQSGHETLSLFIRGWASKKFMTGCVILLPIAVTFYTTWWFIHFVDGFFSPIYALLGINIFGFGFLTSIAFIFLVGVFMSSWLGASVLNLGEWFIKRMPFVRHIYNASKQISTAISPDQNTQAFKEVAIIRHPRVGEYAFGFITSTVVLQNYPTEEELCCVYVPTNHLYIGDILLVNSNDVIRPNLSVREGIEIVVSGGMSMPQILSTLDKPLASIGNES
What are the official names of this protein?
Protein LIKE COV 1.
What is the protein family that this protein belongs to?
Belongs to the plant COV1 protein family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNLJ_AZOPC
Sequence: MNIKQKIDNLRQEIDNWNYRYYVIYQPIVSDFEFDKKLKELEKLEAQYPEYYDYYSPTQRIGNDINNNFAQINHIYPMLSLSNTYSWEGINDFYNRIKKILNENFVIACELKYDGVSISLIYESGLLLRAVTRGDGTTGDDVTTNIRTVKSIPLKLYGNNYPRFFEIRGEIVFPWAAFNKINKERIENSEPPFANPRNAAAGTLKTLNPQVVSQRNLDAYLYQLLGDNLSSDSHYENLQLAQGWGFKVSNIIKCCKTIDEIENFINYWGKWKKSLPFAVDGVVLKVDSIRQQSLLGRIAKSPRWAIAYKFQSETVKTTLHSVDFQVGRTGIITPIANLEPVLLSGTIVKRASLHNEDIINALDLHIGDQCYVEKGGEIIPKITGINKEARLTFGNKAVNFPKNCPACNTPLIRFQNETAYYCPNYTQCKPQIKGMITHFASRKAMNINVGEETIETFYRAGLVRDIADLYEIKIDDILQLKRWAEKSAINFVESVQQSKQVPYERVLYGLGIHFVGEVVAKRLAKAFPTIEQLSIANNEQLTTIDGIGNQIAQSVIQYFSNENNLQLIRRLKLYGLQLFTIQKIFIDNKLAGKTFIISGIFRKYSRDKYKELIENNGGKNVSSLSAKTDFILSGVNMGPVKLIKAQRFGIKIISEDEFLKMIE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: F16PA_BURMS
Sequence: MSITRRTTLSKYLIEQQRETHNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGQQATEQSFLQPGTEQVAAGYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNLRIPEDTREYAINASNARHWYEPVKRYIDELNAGAEGPRGENFNMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGLKRILDVQPTGLHQRVPVILGSKNEVERVARYHEQAQS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_SHEPC
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMASSLVRHEIIKTTVAKAKELRRVVEPLITLAKSDSVANRRLAFARTRDAEVVGKLFTELGPRYQERPGGYTRILKCGLRAGDKAPMAYIELVGRPEAAQAVDVEAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HEM1_STRAW
Sequence: MSLLVVGLSHRSAPVSVLERATLTADAQVKLLQDTVAAEPATEAAVLATCNRIELYADVDKFHAGVAELSTLLAQHSGVGLEELTPYLYVHYEDRAVHHLFSVACGLDSMVVGEGQILGQIKDALATAQELHTAGRLLNDLFQQALRTGKRAHSETGIDRAGQSLVTFGLEQLSAGTAVEAWAKGKRALVIGAGSMSSLAAATLARAGVAEVVIANRTPDRAERLAQILTEGDDTDVLARAVPMDAVPAELTRADVAVSCTGATGLVLTAEAVAAAVEGRTGTPVAVREETPASAAGGLAPAGTDEGCPLDLSAVQGATGFSVMGEAAVAGMDAATLEQHAAWVDRGTVDRRDSRRTPEVEAELITALAATVAAGGRLPERRRPEPVVEAPRPAPALALLDLAMPRDIDAAVHRLLGVRLVDIESLAEASADAPMAADVDLVRRIVADEVAAFGAAQRAAHITPTVVALRTMAADVVANEIARLDGRLPGLDEKQRGEITQTVRRVVDKLLHAPTVRVKQLAAEPGGAGYADALRTLFDLDPETVAAVSRADDRDTSDSTENAKNRGRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PPE10_MYCTU
Sequence: MTSPHFAWLPPEINSALMFAGPGSGPLIAAATAWGELAEELLASIASLGSVTSELTSGAWLGPSAAAMMAVATQYLAWLSTAAAQAEQAAAQAMAIATAFEAALAATVQPAVVAANRGLMQLLAATNWFGQNAPALMDVEAAYEQMWALDVAAMAGYHFDASAAVAQLAPWQQVLRNLGIDIGKNGQINLGFGNTGSGNIGNNNIGNNNIGSGNTGTGNIGSGNTGSGNLGLGNLGDGNIGFGNTGSGNIGFGITGDHQMGFGGFNSGSGNIGFGNSGTGNVGLFNSGSGNIGIGNSGSLNSGIGTSGTINAGLGSAGSLNTSFWNAGMQNAALGSAAGSEAALVSSAGYATGGMSTAALSSGILASALGSTGGLQHGLANVLNSGLTNTPVAAPASAPVGGLDSGNPNPGSGSAAAGSGANPGLRSPGTSYPSFVNSGSNDSGLRNTAVREPSTPGSGIPKSNFYPSPDRESAYASPRIGQPVGSE
What is the function of this protein?
Plays a major role in the integrity and stability of the capsule.
What are the official names of this protein?
PPE family protein PPE10.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: ZN277_DROME
Sequence: MEHEVAVSGGDSSLEEITGSSKLKPSKNTAIKCLKCDKVYIFPSDKDDCLAHLYMEHRLVIADVEDIALLEDYLQYWEKEFHTHEFEQYCTTMFLDQLPDGKYAKNEKYYLLCDILPQDYELRRRLKEKRLSEALERHQFELTDRTFSKECLFCRAIIKGLRADYLDHLFDKHFLLVGKPEKLVYVDELLDHLEENLNRLMCLYCEKIFRDRPTLKEHMRKKGHKRINPNRREYDKYFLINYNRVPTAPTPRKQHLQKRRRETASVSTVADPETGSVDFDKHFARPDSDGEHDSDWSDWAADGEPSSIKCLFCHHLGDNFTALKKHMHEVHRLDFEKATSSLNFYQRVKVVNYLRRQMCLLRCVTCDLQFDEEELLVEHMAQESHHGIGDKESWDKPEFFFPYIENDGLLCVLDDSGGDDPDVDTVRIISEDSLAQINKDAERLSLENFKLL
What is the function of this protein?
DNA binding protein which is involved in the positive regulation of both basal and inducible transcription (PubMed:33456983).  Mainly localizes to active promoter sites and interacts with components of various transcription and replication regulatory complexes, such as the ORC, SAGA, THO, TFIID and SWI/SNF complexes (PubMed:30713769, PubMed:33456983).  It may therefore regulate transcription by promoting the association of these complexes to their binding sites (PubMed:30713769, PubMed:33456983).
What are the official names of this protein?
Zinc finger protein 277.
What is the protein family that this protein belongs to?
Belongs to the ZNF277 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly localizes to the cell nucleus (PubMed:30713769). Associates with chromatin (PubMed:33456983).
Protein: AGLE_RHIME
Sequence: MKRSLLIGVAAFALLAGTAGLAGTAGAADLKFKPGEDSRFNWASLEEFKKGHDLKGQTLTIFGPWRGEDEALFKSVYAYFVEATGVELKYSSSENYEQQIVIDTQAGSPPDVAILPQPGLIADLAAKGLLTPLGDETKQWLLDNYAAGQSWVDLSTYNGKDGTSALYAFPYKIDVKSLVWYVPENFEDAGYEVPKTMEELKALTEKIAEDGEKPWCIGLGSGGATGWPATDWVEDLMLRTQPAETYDKWVKNEIPFTDAAVTGALEEFGWFARNDAFVDGGAAAVASTDFRDSPKGLFSSPPKCYLHHQASFIPSFFPEGKVVGEDADFFYMPPYESKKELGNPVLGAGTLAMITKDTPAARAFIEFLKTPIAHEVWMAQTSFLTPYKSVNVDVYGNPPLKKQGEILLNATTFRFDGSDLMPGKIGAGAFWTGMVDFVGGKSSADVAAGVQKAWDSIK
What is the function of this protein?
Part of the binding-protein-dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose.
What are the official names of this protein?
Alpha-glucosides-binding periplasmic protein AglE.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: EFC11_RAT
Sequence: MFLSEAGARPRAGEISASERRKWVEVFKACDEDNKGYLSREDFKVAIVMLFGYKPSKIEADAVMSSANPDTSGVSLEGFLNVVQRKKEAQLYRNEIRHIFTAFDVHYRGFLTLEDFKRAFSQVAPKLPSRTVLEVFREADQDSDGHVSFRDFEYAMNHGKAK
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 11.
Protein: RUVB_THEMA
Sequence: MSEFLTPERTVYDSGVQFLRPKSLDEFIGQENVKKKLSLALEAAKMRGEVLDHVLLAGPPGLGKTTLAHIIASELQTNIHVTSGPVLVKQGDMAAILTSLERGDVLFIDEIHRLNKAVEELLYSAIEDFQIDIMIGKGPSAKSIRIDIQPFTLVGATTRSGLLSSPLRSRFGIILELDFYTVKELKEIIKRAASLMDVEIEDAAAEMIAKRSRGTPRIAIRLTKRVRDMLTVVKADRINTDIVLKTMEVLNIDDEGLDEFDRKILKTIIEIYRGGPVGLNALAASLGVEADTLSEVYEPYLLQAGFLARTPRGRIVTEKAYKHLKYEVPENRLF
What is the function of this protein?
Promotes Holliday junction (HJ) branch migration in conjunction with RuvA.  Subunits can be free, ADP- or ATP-bound; nucleotide binding changes during the reaction cycle (PubMed:11478862).  Has a DNA-dependent ATPase activity; dsDNA and supercoiled DNA but not ssDNA stimulate activity (PubMed:8626340, PubMed:11478862).
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: QUEF_ALIFM
Sequence: MTKYTNADELKSLTLGQKTEYKHTYEPELLQAVPRSLNRDDLALGDELPFVGCDVWTLYELSWLNQNGLPQVAVGEVALPATSPNLVESKSFKLYLNSFNQTKFTSWDEVKETLVKDLSACAGETVKVDVFPVQRYSQQPIVDMQGECIDDQDIIIDDYEFNAAYLESSTSDAEIEETLHSHLLKSNCLITNQPDWGSVEIQYKGKKIDREKLLRYLISFRQHNEFHEQCVERIYTDIMKYCAPESLTVFARYTRRGGLDINPFRSSHLLAPKDNLRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_BUCAT
Sequence: MIQEQTILHVADNSGARSAMCIKVLGGSRRRYAAIGDVIKITIKEAIPRGKVKKGEVLKAVVVRTKKGVRRSDGSVIRFDTNACVVLNNNEQPIGTRIFGPVTRELRTEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: COBD_SINSX
Sequence: MSETILLILALALVIDRVVGDPDWLWARVPHPVVFFGKAIGFFDARLNREDLEDSARKFRGVVAILLLLGISAWFGHLLHRLFAVLGPLGFLLEAVLVAVFLAQKSLADHVRRVAGGLRQGGLEGGRAAVSMIVGRDPKTLDEPAVCRAAIESLAENFSDGVVAPAFWYAVAGLPGLLAYKMLNTADSMIGHKSPKYLHFGWASARLDDLANLPAARLSILLISAGALIHRGASAAKDALTVALRDHGLHRSPNSGWPEAAMAGALDLQLAGPRIYGGVKVSEPMINGPGRAVATSEDIDAGIAVFYGACTVMAGFVLAIAMI
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y107_CAUVN
Sequence: MTEASAPLIDVDPRLLEVLVCPVTRGPLEYDRAKGELISRAAKLAYPIRDGVPIMLPEEARELEG
What are the official names of this protein?
UPF0434 protein CCNA_00107.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: MINE_SALPA
Sequence: MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.