PharMolix/UniProtQA huggingface dataset:
Protein: ACCD_IDILO
Sequence: MSWIERILAKPKINKRRGVPEGVWSKCTACGNIIYKADLERSLNVCPKCDHHMRVTGRSRLDIFLDKDNREEIGTDLEPKDVLRFKDSKKYKDRIAAAQKSTGENDALIAEKGTVKGVPLVAVAFDFNFMGGSMASVVGAKFVLAAEVCLKHRIPLVCFSASGGARMQEALMSLMQMAKTSAALARMSEEGLPFISILTDPTMGGVSASLAMLGDIHIAEPKALIGFAGPRVIEQTVRQTLPEGFQRAEFLLEHGAIDMITDRRDMRDTVARLLAKMQNLPSTEATEVSVNE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXC1A_XENLA
Sequence: MQARYSVSSPNSLGVVPYLSGEQSYYRAAAAAAAAGGGYTGMAAPMSMYSHPAHEQYQAGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKDATKEDKERLLKEHHGSQSAAAQQQRQQQQSQAQAEQDSNSQPVRIQDIKTENGTSSPPQSMSPALSAVPKIESPDSSSSMSSGSPHSIPSNRSMSLEAAESHHPHHQQHSQGFSVDNIMTSLRGSPQGSAELPSPLISSSRTGIAPSLSLSYSPGQGSIYSSPCSQGTSSGGGAGTYHCNMQAMSLYSGDRSGHLTPANTPAATTVEETLPDYSISTTSAQSHGNQEHPHQGRLPSWYLNQTGELGHLAGATYPGQQQNFHSVREMFESQRLALNSSPVNGNSSCQMSFPPSQSLYRTSGAFVYDCSKF
What is the function of this protein?
DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development.  Acts either as a transcriptional activator or repressor.  Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes.  Upon DNA-binding, promotes DNA bending.  Required for cell viability and resistance to oxidative stress in the eye.  Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1-mediated signals.  Involved in epithelial-mesenchymal transition (EMT) induction by increasing cell proliferation, migration and invasion.  Involved in chemokine-induced endothelial cell migration.  Plays a role in epidermal keratinocyte terminal differentiation.  Essential developmental transcriptional factor required for mesoderm-derived tissues formation, such as the somites, skin, bone and cartilage.  Plays a role in the development and maintenance of mesenchymal niches for haematopoietic stem and progenitor cells (HSPC).  Plays a role in corneal transparency by preventing both blood vessel and lymphatic vessel growth during embryonic development in a VEGF-dependent manner (By similarity).  Plays a role at the gastrula stage for expression of several mesodermal and endodermal genes (PubMed:17705306).  At the late neurula stage, regulates expression of adhesion genes to maintain cell adhesion in the mesodermal germ layer (PubMed:17705306).
What are the official names of this protein?
Forkhead box protein C1-A, FoxC1, Fork head domain-related protein 11, XFD-11.
What are the subcellular locations of this protein?
Nucleus.
Protein: FYV10_PICST
Sequence: MSEPSLNFHIQSHSTQFRIPTELIKKNFKTIQKLVEKQKKQMTDDVAKIKKNPNIPTAMKLAMVRKSIKSFEGFQKKLQASIAKDEELRSRLIARIEHLALISEYCITQDKTKTQVEKPSQPQSQNEDTEEKEHSTKDDNDKYLDLHNPNLITWYRDQTNLLIIDYLIKSNTRTDHNIGLLLLKSLSESNPKYMKLIDYDLFESFNKVYVSIMEDHDLTLVIAWFNENRNFLKKANSNLEFEINYCRFLSLIEKGDVNEAIKFSSINLSPYGNVSNYQDTDRANHEHNLNRLKEIGGLLVYMAINEEKRTRNDKIAFSSNLLINSPRFHEYEKLLSDERWDSLSMCFVENFTKLYGISKNYPIFIYLSAGLASLKTKSCYHNTENTIFRENQEINVTDESIYKKDLTVLTDKKYRGSNQYYKLLNKINNCPVCSPELYKLSRNLPYAQLITSIFNNPFKLPNGNIYPFDKLLNPSEKYLSEKNTLLRMGKIKDPLTREIFLIDTCIRVYPA
What is the function of this protein?
Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
What are the official names of this protein?
Protein FYV10.
What is the protein family that this protein belongs to?
Belongs to the FYV10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DLDH_STAAW
Sequence: MVVGDFPIETDTIVIGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALLHASHRFVEAQHSENLGVIAESVSLNFQKVQEFKSSVVNKLTGGVEGLLKGNKVNIVKGEAYFVDNNSLRVMDEKSAQTYNFKNAIIATGSRPIEIPNFKFGKRVIDSTGALNLQEVPGKLVVVGGGYIGSELGTAFANFGSEVTILEGAKDILGGFEKQMTQPVKKGMKEKGVEIVTEAMAKSAEETDNGVKVTYEAKGEEKTIEADYVLVTVGRRPNTDELGLEELGVKFADRGLLEVDKQSRTSISNIYAIGDIVPGLPLAHKASYEAKVAAEAIDGQAAEVDYIGMPAVCFTEPELATVGYSEAQAKEEGLAIKASKFPYAANGRALSLDDTNGFVKLITLKEDDTLIGAQVVGTGASDIISELGLAIEAGMNAEDIALTIHAHPTLGEMTMEAAEKAIGYPIHTM
What is the function of this protein?
Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of pyruvate complex, Membrane-bound ribosome protein complex 50 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: ASK6_ARATH
Sequence: MMIKGMAEDDCADNGIPLPNVTSKILLLVIEYCKKHVVESKEEDLKKWDAEFMKKMEQSILFDVMMAANYLNIQSLLDLTFSNCR
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity).
What are the official names of this protein?
SKP1-like protein 6, AtSK6.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROC_MYCPA
Sequence: MGPVLRWITAGESHGRALVAVLEGMVAGVEITSTDISEQLARRRLGYGRGARMSFERDAVSVLSGVRHGLTLGGPIAVEIGNTEWPKWETVMATDPVDPAQLADSARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTIARSFLRQALGVEVLSHVIAIGPSAPYEGPPPGPGDLPAIDASPVRAYDEAAEQAMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSFTSGDNRLDGQLAAAVMGIQAIKGVEIGDGFATARRRGSQAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDMATGDEAVAIHQRSDVCAVPAAGVVVEAMVALVLARATLQKFGGDSLAETRRNIDAYRRAVAEREAPAARGTA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ATPD_HAEI8
Sequence: MSELTTIARPYAKAAFDFAIEQSAVEKWTEMLGFAAAVAEDETVKAYLSSSLSAQKLADTVISICGEQLDQYGQNLIRLMAENKRLSAIPAVFEEFKHHVEEHQAIAEVEVTSAQPLNATQIEKIAAAMEKRLARKVKLNCNVDNALIAGVIVRTEDFVIDGSSRGQLTRLANELQL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PXPA_RUEPO
Sequence: MTRVDLNADMGESFGPWKMGDDDSLLKIITSANIACGFHAGDPDVMAKTMALAAENGVGIGAHPGFPDLQGFGRRNMKVPHDSLRNLVRYQLGAALGMARAVGTQVRHLKLHGALANMCSVDQDMARACYQGALDVDPDIIIMVLAVTKQEQAVRELGCKWVGEIFADRAYNDDGTLVDRALPGAVIHDPDLAGPRMLKMVRAGAIITESGKHLETSVDTICLHGDGPTAVQIARSVRACLEEGGVSVTAFER
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: Y2597_MYCTO
Sequence: MGNLLVVIAVALFIAAIVVLVVAIRRPKTPATPGGRRDPLAFDAMPQFGPRQLGPGAIVSHGGIDYVVRGSVTFREGPFVWWEHLLEGGDTPTWLSVQEDDGRLELAMWVKRTDLGLQPGGQHVIDGVTFQETERGHAGYTTEGTTGLPAGGEMDYVDCASAGQGADESMLLSFERWAPDMGWEIATGKSVLAGELTVYPAPPVSA
What are the official names of this protein?
Uncharacterized protein MT2673.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PYRR_HAEIN
Sequence: MEKIIIDHDRFLRTISRISHEIIEKHQTLDDLVIVGIKRRGAEIAELLQRRVEELSSINLPSMELDITFYRDDLTLVDQEDKMPVYSGSSQYLNIQDKTVILVDDVLFTGRTIRAAMDALTDFGRAAKIELVIFVDRGHRELPIRADYVGKNVPTSRDELVQVRTEKQDGCYEVAILGK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: G6PI_HALSA
Sequence: MRIDIGAALDATATPGVPPDALDRLDDRVAHAHDRITAGMDGDEFGYAALNLPRTVDVDAITAAADAVADADTLVTVGIGGSALGAATLVDALGDDDLDYHALDNVDPAHVTRLLDRIDLSTSAVHVVSRSGTTAETLANFLVVRDAMDDAGVDWTARTLVTTGDDGPLRALADTHDLPVLDAPRGVPGRFAALSTVALPAAAIAGVDVGELVAGAADGRAALAGSLEDCSAYAYGATAYALDQRGAGVNAMLPYAERLETFAEWFAQLWAESLGKDGVGQTPARALGATDQHSQLQLYRAGPRDKLVTMLRPASRPDCAIPEAELADIDYLTGGDLGALLDAEFEATAASLAASGVPTVRVEVPAVDARSVGRLLFDFEAACVLAGELYGVETFTQPAVEWGKNAARELLRGEDPLPETETHIVE
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Probable glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP1M_CAEEL
Sequence: MATSAMFILDLKGKTIISRNYRGDIDMTAIDKFIHLLMEKEEEGSAAPVLTYQDTNFVFIKHTNIYLVSACRSNVNVTMILSFLYKCVEVFSEYFKDVEEESVRDNFVVIYELLDEMMDFGFPQTTESRILQEYITQEGQKLISAPRPPMAVTNAVSWRSEGIKYRKNEVFLDVIESVNMLASANGTVLQSEIVGSVKMRVYLTGMPELRLGLNDKVLFEGSGRGKSKSVELEDVKFHQCVRLSRFDTDRTISFIPPDGAFELMSYRLTTVVKPLIWIETSIERHSHSRVSFIIKAKSQFKRRSTANNVEIIIPVPSDADSPKFKTSIGSVKYTPEQSAFVWTIKNFPGGKEYLLTAHLSLPSVMSEESEGRPPIKVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGEYEMRMK
What is the function of this protein?
Component of the adaptor complexes which link clathrin to receptors in coated vesicles (Probable).  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (Probable).  Required for many aspects of development and behavior, including negative regulation of vulval differentiation (PubMed:8288128).  Required for the dendritic localization of potassium channel kvs-4 in the cholinergic motor neuron DA9 (PubMed:26762178).
What are the official names of this protein?
AP-1 complex subunit mu-1-I, Clathrin assembly protein complex 1 mu-1-I medium chain, Clathrin coat assembly protein AP47, Clathrin coat-associated protein AP47, Golgi adaptor AP-1 47 kDa protein, HA1 47 kDa subunit, Mu1-I-adaptin, Uncoordinated protein 101.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, dendrite. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex (By similarity). Association with kvs-4, targets kvs-4 to dendrites (PubMed:26762178).
Protein: HLDE_HYPNA
Sequence: MSSRLSGLLDRAAGKRVLCIGDVMLDRFIYGVVDRISPEAPVPVLRHSREASMPGGAANVARNLASLGLEPVLIGACGDDDAGRELLSIFDQDLSLSVRLVTAKGRPTTLKCRFVAGGHQLLRVDTENVAPVSEATEEELIGILSREAPGSAAILISDYAKGLLTDRLLKAVTKLAADLNIPLIADPKGRDFARYGAVDILKPNAFELSAAVHRSISTDEEAALALREALDTLPAKAIIVTRAARGISYIGQDGNVHHEAGRAREVFDVSGAGDTSLAALATAIAGGGTLSDAVHLAIAASGIAVGKAGTATVSAEEIKAALSVAGPVGRAGLLPMDAMIGQVERWRAAGLKIGFTNGCFDILHPGHIRVIEQARAHCDRLVVGLNSDNSVKRLKGPLRPINNEQARADVLSALSAVDGVIIFDTDTPLDAIAALNPDVLVKGGDYTRESIVGADIVEARGGEIVIVPLVAGHSTTAIIARSETGK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RL6_METS3
Sequence: MVVAAAIREEIEIPEGVEVIINNNEVTVKGPNGEDSRKFTYPNVDITEVENNVVLETSFPRKKDKAMIGTTKAHISNMITGVTDGFEYHMKIVFAHFPMTVKVNKDVVVIDNFLGERHPRTAKVVGSAKVVVKGDEVTITGINKEHVGQTMANLEQATKIKGRDPRVFQDGIYLISKE
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: NDUS8_NEUCR
Sequence: MLTTTASSAAAVARQLTTRRVIAPSFVSQAIRTYATPAGPPPKGFRIPTPKTWDQEEEHVLDKNGRYFLLTEMFRGMYVAMEQFFRPPYTIYYPFEKGPISPRFRGEHALRRYPSGEERCIACKLCEAVCPAQAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQESCPVDAIVESPNAEYATETREELLYNKEKLLSNGDKWEPELAAAIRADSPYR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.  May donate electrons to ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial, Complex I-23kD, CI-23kD.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NANP_RAT
Sequence: MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEVICDKVQVKLSKECFHPYSTCITDVRTSHWEEAIQETKGGADNRKLAEECYFLWKSTRLQHMTLEEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAIVVGGEQKEEKPAPSIFYHCCDLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKSGGVPLTSSPMPHYMVSSVLELPALLQSIDCKVSMSV
What are the official names of this protein?
N-acylneuraminate-9-phosphatase, Haloacid dehalogenase-like hydrolase domain-containing protein 4, Neu5Ac-9-Pase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. NANP family.
Protein: ATP6_BOSMU
Sequence: MNENLFASFITPMILGLPLVTLIVLFPSLLFPTSDRLVNNRFVTLQQWMLQLVSKQMMSIHNPKGQTWTLMLMSLILFIGSTNLLGLLPHSFTPTTQLSMNLGMAISLWAGAVITGFRNKTKTSLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVRLTANITAGHLLIHLIGGATLALMSISATTALITFIILILLTILEFAVAMIQAYVFTLLVSLYLHDNT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BETA_ECOLI
Sequence: MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNALDLDNWAQEPGLENWSYLDCLPYYRKAETRDMGENDYHGGDGPVSVTTSKPGVNPLFEAMIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRTHAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAELLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGGTGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSPSRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISPGVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIMPQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPVRAKK
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CYBP_HUMAN
Sequence: MASEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAKGDTEF
What is the function of this protein?
May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins.  Probably serves as a molecular bridge in ubiquitin E3 complexes.  Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
What are the official names of this protein?
Calcyclin-binding protein, CacyBP, hCacyBP, S100A6-binding protein, Siah-interacting protein.
Protein: AROE_NITMU
Sequence: MSDLYAVIGNPVAHSKSPLIHAGFARQSGQDVRYEAILAPLDGFVETVAAFRQRGGKGANVTVPFKLEAHTLSSCLTERAKAAGAVNTLVFGADDILGDNTDGAGLVRDVAVNLGYALDDRRVLLMGAGGAARGVIRPLLEHEPAALVIANRTPQKADDLQRLFASSGNVLSAAYEDLRGQEFDLVINATSASLQGDLPPLPKGIFAGASLAYDMMYGKGLTSFLQFAQQQGAARLADGIGMLVEQAAESFFLWRGIRPETEPVIGMLRSSLGSP
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: F13B_MOUSE
Sequence: MMTLRHLPFILLLILSGELYAEEKQCDFPTVENGRIAQYYYTFKSFYFPMSVDKKLSFFCLAGYATESGKQEEQIRCTAEGWSPNPRCYKKCLKPDLRNGYVSNDKVLYKLQERMSYGCSSGYKTTGGKDEEVVHCLSAGWSSQPSCRKEQETCLAPELEHGNYSTTQRTFKVKDIVAYTCTAGYYTTTGKQTGEAECQANGWSLTPQCNKLMCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFGWYPESPICEGRRNRCPPPPVPLNSKIQPHSTTYRHGERVHIECELNFVIQGSEELLCENGKWTEPPKCIEEKEKVACEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRGSSTITCNRGRWTLPPECVENIENCKPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGSETSRCEQGAWSSPPVCLEPCTIDVDHMNRNNIQLKWKYEGKILHGDLIDFVCKQGYNLSPSIPLSEISAQCNRGDVRYPMCIRKESKGMCASPPVIRNGDIVSSAARTYENGSSVEYRCFDNHFLQGSQNVYCVDGVWTTPPSCLEPCTLSFVEMDKNYLQLKWNFDNRPLILHGEYIEFMCKRDAYISETSIAGSVLRVQCDRGRLKYPKCTPRDRRLSFQEALRTRRQMEKR
What is the function of this protein?
The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin.
What are the official names of this protein?
Coagulation factor XIII B chain, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain.
What are the subcellular locations of this protein?
Secreted.
Protein: ALYS_ENTFA
Sequence: MKKESMSRIERRKAQQRKKTPVQWKKSTTLFSSALIVSSVGTPVALLPVTAEATEEQPTNAEVAQAPTTETGLVETPTTETTPGTTEQPTTDSSTTTESTTESSKETPTTPSTEQPTADSTTPVESGTTDSSVAEITPVAPSATESEAAPAVTPDDEVKVPEARVASAQTFSALSPTQSPSEFIAELARCAQPIAQANDLYASVMMAQAIVESGWGASTLSKAPNYNLFGIKGSYNGQSVYMDTWEYLNGKWLVKKEPFRKYPSYMESFQDNAHVLKTTSFQAGVYYYAGAWKSNTSSYRDATAWLTGRYATDPSYNAKLNNVITAYNLTQYDTPSSGGNTGGGTVNPGTGGSNNQSGTNTYYTVKSGDTLNKIAAQYGVSVANLRSWNGISGDLIFVGQKLIVKKGASGNTGGSGSGGSNNNQSGTNTYYTVKSGDTLNKIAAQYGVSVANLRSWNGISGDLIFVGQKLIVKKGASGNTGGSNNGGSNNNQSGTNTYYTIKSGDTLNKIAAQYGVSVANLRSWNGISGDLIFAGQKIIVKKGTSGNTGGSSNGGSNNNQSGTNTYYTIKSGDTLNKISAQFGVSVANLQAWNNISGSLIFAGQKIIVKKGANSGSTNTNKPTNNGGGATTSYTIKSGDTLNKISAQFGVSVANLRSWNGIKGDLIFAGQTIIVKKGASAGGNASSTNSASGKRHTVKSGDSLWGLSMQYGISIQKIKQLNGLSGDTIYIGQTLKVG
What is the function of this protein?
Hydrolyzes the cell wall of E. faecalis and M. lysodeikticus.  May play an important role in cell wall growth and cell separation.
What are the official names of this protein?
Autolysin, Beta-glycosidase, Peptidoglycan hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 73 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RRP3_NEOYE
Sequence: MEIKNLSKFTLKVLWLENNIAIAIDQIVGNGTSPLTSYFFWPRNDAWEELKAELESKPWIAERDRIELLNKTTEVINYWQEEGKKHSLAKAQARFPRIYFFG
What is the function of this protein?
Probably a ribosomal protein or a ribosome-associated protein.
What are the official names of this protein?
Probable 30S ribosomal protein 3, chloroplastic, PSRP-3.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cS23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PHNX_VIBVU
Sequence: MNKSPIQAVIFDWAGTIVDFGSFAPTSIFVEAFKQGFDFEIDLEEAREPMGLGKWDHIQAVGRIPAVDKRWNEKFGRSMISEDIDAIYAAFMPLQKAKVADHAEPILNAIEVVNGLKDKGIKIGSCSGYPREVMDVLIPVAADYGYQPDYVVATDDLPQGGRPAPFMALKNVIELGVSDVKACVKVDDSAPGIFEGHNAGMWTVGLLLSGNEAGLTFEEYQAADEATLEKAREKARAKLLKSSPHYLIDTIADFPEVVADIERRLAAGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: KCY_CLOD6
Sequence: MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYKCLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKEVRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKGYNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHA_METJA
Sequence: MEFKIVNTICPYCGVGCGLGLVVKDGRVIGIHPNKRHPINEGKLCAKGNYCYQFIHSKDRLTKPLIKKESGFVETTWNKALEVIAENLKTYKDEIGFFSSARCTNEDNYILQKFARVALKTNNIDHCARLUHSATVTGMSACFGSGAMTNSIEDIELADCILIIGSNTFEQHPLIARRIMRAKDKGAKIIVIDPRRTITAKNSDIYLQIIPGTNVALINAMINVIIKENLIDKEFIKNRTEGFEKLKEIIKKYTPEYASKICGVDKELIIESAKIYGNAERASIIYCMGVTQFTHGVDAVKALCNLAMITGNIGKEGTGVNPLRGQNNVQGACDMGALPNVFPGYQKVEDGYKLFEEYWKTDLNPNSGLTIPEMIDESGKNIKFLYIMGENPIVSDPDVKHVEKALKSLDFLVVQDIFLTETAKLADVVLPAACWAEKDGTFTNTERRVQLIRKAVNPPGEALEDWIIIKKLAEKLGYGDKFNYNKVEDIFNEIRKVTPQYRGITYKRLKIDGIHWPCLDENHSGTKILHKDKFLTDNGRGKIFPVEYREVAELPDKDYPFILTTGRIIFHYHTGTMTRRCKNLVEEINEPFIEINPDDAKSLKIENGDLVKVISRRGEITAKARITEDIKKGVVFMPFHFVEANPNVLTNTALDELCKIPELKVCAVKIERI
What is the function of this protein?
Catalyzes the oxidation of formate.
What are the official names of this protein?
Formate dehydrogenase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.