PharMolix/UniProtQA huggingface dataset:
Protein: RM02_YEAST
Sequence: MWNPILLDTSSFSFQKHVSGVFLQVRNATKRAAGSRTSMKDSAGRRLGPKKYEGQDVSTGEIIMRQRGTKFYPGENVGIGKDHSIFALEPGVVRYYLDPFHPKRKFIGVALRRDLKLPSPHFEPTVRRFGRFELTNKRAAYKEENSISRKDYLAKPNILKQLEVRESKRKELQDKLSKVLRDELKLDIKDIELATSYLIRVRASLKNGYPIEDARFNSRYYLKEEERLKARRESWTNEKLSESLSKIDECSDLLNSSTSFNNKLELHQYISEQEKQALKAKLLEDLEKSQHLETKKDKNYIKALFKDACNFLTLSEEVHLRRKYLKSVFPETDSTVETKSGKKSIVSRRFDYTKNKVEVIARSRRAFLSKL
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L2, mitochondrial, Mitochondrial large ribosomal subunit protein bL27m, YMR6, YmL2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: YBOE_SCHPO
Sequence: MSFNPAAGLLGKLKKLWNDTKNDYLEWERSQQGQISESVVKNHSPSKRKRRPSKEPSLSPKRRKNILNDQKKDEESIPNAGTQSQNFTHLSASKIRISDEDRIKPLVDLNQDHSFDMAYLTPASAPPPRFRFVPPKSDAKSHSAPRSLEGVTSLSDSHFNSLEANLKAISKDSNNKAHNNRYDESSLTNPEFSILVERLKSIEENLQSLQERISHCERSVSLSPSFAPPSNVKSPVQQHRSFVSSSARAKKNWGRQSNSPNSNKKTDHAYPGASMNTERGLIQNLEDSDDIHEESSDTLEEPLLINELNRTSFLNSNNNLKLNEAEENQNLLNLRSPKSSGKADNLTIKSSSNIDKVTSNDLYLDNNLQSHFKVTESQPTNLGRKEYSNSPFSIRARKDAATTSSSFESYHNTQTIQSPMKFTKATPLKDNESASVDESKVNVLSENQSLQADTATLEQLTPIPKARWNQLANKHPSLSNSAASPPVSSPGLRRSHIPVHEGLKHTRDGVAETKDALAKLREKMQERLKNHTS
What are the official names of this protein?
Uncharacterized protein C2G2.14.
Protein: RS9_METNO
Sequence: MATLQSLADLGQANKAALATADTEAPVHVQKLDAQGRAYATGKRKDAVARVWIKPGAGTITVNDRPVDTYFARPVLRMILQQPLHVANRVDQYDIVVTVTGGGLSGQAGAVRHGLARALTYYEPELRSPLKREGFLTRDPRVVERKKYGRKKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: OPSD_SCYCA
Sequence: MNGTEGENFYIPMSNKTGVVRSPFDYPQYYLAEPWKFSVLAAYMFFLIIAGFPVNFLTLYVTIQHKKLRQPLNYILLNLAVADLFMIFGGFPSTMITSMNGYFVFGPSGCNFEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSNFRFGSQHAFMGVGLTWIMAMACAFPPLVGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFSIPLTIIFFCYGRLVCTVKEAAAQQQESETTQRAEREVTRMVIIMVIAFLICWLPYASVAFFIFCNQGSEFGPIFMTIPAFFAKAASLYNPLIYILMNKQFRNCMITTICCGKNPFEEEESTSASASKTEASSVSSSQVAPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: COAA_CLAM3
Sequence: MPDTATGHPTSHGNVSPFVEIARADWAALAPATHLPLRETELVQLRGIGDRLDMHEVEDVYLPLSRLLNLYVTGTKKLHRDTSAFLGERAKSTPFIIGVAGSVAVGKSTVARLLREMLARWDDTPRVELVTTDGFLHPNAELQRRGLMERKGFPESYDRRALLRFVTQVKSGVPEVRAPFYSHLAYDIVPGAEVVVRQPDVLIIEGLNVLQPAASGAKLAVSDLFDFSIYVDARTHDIAQWYEERFLSLQRGAFSNPRSYFHRYAELSPAEAVARARGIWSAINEPNLEQNIRPTRSRATLVLRKDADHSVANVLLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y319_BORPE
Sequence: MTDSHRPDADDIPDDDELSTDFSNQFLLAMPGVVEGSLAGTVIYICEHTRRGALGLVINRPTDLTLATLFERIDLKLEIGPVKDEMVFFGGPVQTDRGFVLHAPAGDYTSSINLGELALTTSRDVLQAVADGNGPARMLVTLGYAGWGAGQLESEMAQNSWLSVGADSHIIFDVAPEDRYPAALKLLGVDPVMLAGGAGHA
What are the official names of this protein?
UPF0301 protein BP0319.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: YETK_BACSU
Sequence: MKKRLSLDRRFLPYIKKAGGVLVKKQMGAYVSLAAAMAIVGSSVVVGKLMVERIPVFLSSGLRFLIASVVLLMLLFCIEKGFPALTKKDVFVLLVQSFTGVFLFSICLLYGVQYTTGTESGILTSTTPMLIGILSFFLLREKIEKKTLIGILLAVCGVMAINLFGAGSQDGTPHALFGNMLIIAAVIGEALFTLMAKLLSPHISALAISTFVSLFGFLFFLPFALFEASSFDYSVPTVLDWSYVLYYALFVTVLAFYLWYSGVTKVPAGVSGIFTSVLPVSAVILSGVILKEPFEFVHFIGIACVIGGIFVTVIKKKQPDAYPAAEEKTL
What are the official names of this protein?
Uncharacterized transporter YetK.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DDL_METCA
Sequence: MEKRIQQASKFGKVAVLMGGSAAEREISLKSGKAVLEALRSGGIDAEGIDVGRDLIAPLLERRFDRVFNVIHGRGGEDGVLQGALACLRVPCTGSGVLASALSMDKLRTKLCWTGAGLPTPPWLRLDSPDDLERCRQALGFPVIVKPAEEGSSIGMSRAATAEELAQAWERASGYGCAVFAERWIDGVEYTGGMLKGVPLPLIRLETPHAFYDFDAKYRADTTRYHCPCGLDTGREAELQALVLRACQIVGVSGWGRVDLLVDRSGQPWLIEVNTVPGMTDHSLVPMAAKAAGIDFQELVWHILETSFA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPX_STRAW
Sequence: MIPPHRCLTDPLLQGSWPGYLPPMPKRARRMRLTTWRSPVTAVIAALLAAFLTPAAAHGAPRESAPVYSYENAIRESVWVDTRLDGDGDGKTDRVAVDVVRPRELARQGRKIPVIMDASPYYSCCGRGNESQKKTYDANGDVVRMPLFYDNYFVPRGYAFVGVDLAGTNRSDGCVDVGGRSDIQSAKAVIDWLNGRAHGYTSRTGTARAKATWTNGRTGMIGKSWDGTVANGVAATGVKGLKTIVPISAISSWYDYYFAKGAPLYDSGPDWLSDYVDSPDARTKCAAVQRKLVDEAPRTGDWTSLWTERDYVKDASKVRASVFLVHGMQDLNVRAKNFGQWWSALAKNGVERKIWLSQTGHVDPFDFRRTAWVDTLHRWFDHELLGYDNGVDREPTADIERHPDQWVTSTLWPPRGTDAVTLRPGTGTQAGVGTLGLRTGSGTETFTDDPRLSETDWAAHIDESTASKAGFVTAPLAGDVRLSGSSKVTVTATPTTSTAHLSAVLVDLGPDTIRDYADGGEGITTLTDRTCWGASTAGDSACFKNTRATTAAVDYTVLSRGWADLGNHASARKGVPLTPGKAYTITLDLAATDHVVPKGHRLALIVAGTDKDLIDPPSSTPTLTLDLARTSARVPLVGGAAAFTRATAQSGTAADATVLDGVREPHTAHRVPGGGL
What are the official names of this protein?
Putative Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
Protein: KAD2_PICGU
Sequence: MSDDLKQVVNQLQDRITQLEKKAGIVPNVPKSIRMVLIGPPGAGKGTQAPNLKEKFCACHLATGDMLRAQVTAKTELGVQAKKIMDQGGLVSDEIMVNMIKSELENNKECSQGFILDGFPRTIPQAEKLDSMLEDRKTPLQKAVELKIEDQLLVDRITGRLVHPASGRSYHKLFNPPKKEMTDDQTGEPLVQRSDDNEEALKKRLGTYHKQTEPIVEYYKKSGIWSGIDASQKPSKVWTDILKCLGQ
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: TRMB_JANSC
Sequence: MTDPHPNRPHRNFYGRRKGHDLRDSQERYLAEDLAKLSPGAVDWDVNPDRTPLDLKERFGGKDIWLEVGFGGGEHLVHQAASNPDVAIIGCEPYINGVAMLLGKIRAAGVGNLAVYPGDARDLFDVLPKGSVAKAFLLYPDPWPKARHHRRRFVTTEHLEPLHRAMRPGAEFRVATDIEDYVRQTMEEVPKAGFEWLAEAASDWREPWCDWVSTRYEQKALREGRVPHYMTFQKRSL
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ABAF_ACIBT
Sequence: MTTTLKKVVAASMVGSVAEWYEFFLYGTASALVFGELFFQQTGNAIDGILAAFALYAVGFLARPLGGLVFGHYGDKIGRKKLLQISLIIVGITTFLMGCIPTFHQIGYWAPTLLVILRLIQGFAFGGEWGGAVILVSEHSPDDRRGYWASWPQTGVPLGNLVATLVLLLLSKNLSPEQFLDWGWRCAFWFSAVVVLIGLWIRKNVDDAEVFKEAQAKQQLLEKQQLGIIEVLKYHKKSVIAGIGARFAENILYYMVVTFSISYLKLVVHKDTSQILLLMFGAHLIHFFIIPFMGHLSDIFGRKPIYLIGAVLTAFWGFVGFPLMDTGNDWLIMLAIVLGLFIESMTYSPYSALMTELFPTHIRYTALSFCYQVAPIMAGSLAPLIALTLLKEFNSSIPISLYLVAASLISIVSILLVKETKGRSLAFKD
What is the function of this protein?
Efflux pump that mediates resistance to fosfomycin (PubMed:27650185).  Probably also involved in the secretion of biofilm matrix that contributes to the pathogenicity (PubMed:27650185).
What are the official names of this protein?
Fosfomycin resistance protein AbaF, Acinetobacter baumannii fosfomycin efflux.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURC_PELPB
Sequence: MELGKTKSVHIVGVGGAGMSAIAELLLKSGFRVTGSDLSSGEVTEKLAEHGAIIYKGHRAEQVAGSDVVVYSSAIRAEDNIELIAAEKAGIPVIKRDEMLGELMRYTYGICIAGTHGKTTTTAMIATMLIESDESPTVMIGGISDYLKGSTVVGEGKYMVIEADEYDRAFLKLTPTIAVVNSLESEHMDTYGTLDELKEAFVAFANKVPFYGRVICCVDWPEIRKIMPKMNRLCTTFGIDEPADVMAFDIVLDNQHTTFSIKAFGQEYRDVSLQVPGRHNVLNALAAFSTGLELGILPERLIAGLGRYSGMRRRFQVKYDNGHGLMVVDDYAHHPTEVKATVRAAKSGWRDSRIVAVFQPHLFSRTREFAHEYGWALSHADMVYVADIYPAREKGVDYPGVDGELIADAVRKAGGKHVEFVADMQNLFTALKEWSVNGNMLLFMGAGDITHLATRVANFCREGVAVQGNEDSQSGFAAS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDKG1_ORYSI
Sequence: MAAGSHGGYRGYEVAREREHDVGVSRRSKEHYHHRHPSRHRDSERRRDGGRSGGRELSNGYSHRRDSPRPPPRRRPSEGRTEDREPGEVSGGSGSERSGERPMKTREPRENGVTRVSKEEAKMSPSKKRKQSPVIWDRNGSQRQARDPVRGIREVDAVVAEIIMHQSHSLPVMSSLSSIGDGHSPMILDVSVDKVQEYEKNRIVDEEEEGYPTMRNILTSRWADAGDEEENVFVPKKKKSVSPVDSIERGSTKKVTSPESGEVLVYNSVRSSSRSSDSGVLQGSANRDLEVEKGDNIDVEKAADDDYPAGHLLDSDFEGEDCRSETPECTRSPRRCINMLQGCRSVDEFERLNTINEGTYGVVFRVRDKRTGEIVALKKVKMEKEREGFPLTSLREMNILLSFHHPSIVEVKEVVVGSNDRDIFMVMEYMEHDLKGVMETMKQPYSQSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNRGELKICDFGLSRQYGSPLKPYTQLVVTLWYRAPELLLGAKDYSTAIDMWSLGCIMGELLSKGPLFNGKSEIDQLDKIFRTLGTPDENIWPGYSKLPGATVKFGKQTHNRLRDKFRAVSFTGGPMLSEAGFDLLNRLLTYDPEKRISAEDALNHEWFRELPLPRSKDFMPTFPALNEQDRRFKKHMKSPDPLEEQWMKEQGNNGDRGLFG
What are the official names of this protein?
Cyclin-dependent kinase G-1, CDKG;1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: RLMN_BIFLO
Sequence: MTTQHPDTPETGITPGGTSGAFRDVLSKDHARRGKPPLHFVDMTPEQRVEKAAELGLPKFRVKQLANHYFGHFDVNAAEFTDFPAAKRSEAAAAFFPQLITEVTRQVADEGTTIKTLWKLFDGSLIESVLMRYPTRTTLCISSQVGCGMDCPFCATGKLGLTRNMSTGEIIEQVRVAAKMMRDGEVAGGEGRLSNIVFMGMGEPMGNYNSVLSAVRQISAMPPEGFGISARNITVSTVGVVPGIKKLTAEGIPVRLAVSLHAPSDELRDELVPMNKRFNTKQVLDAAHDYWLASKRRVSIEYALMRGINDQAEHAQLLAKRLNHYGDNWAHVNPIPLNPIEGSKWTASKPEDEQRFLEILHRAGITATLRDTRGQDIDGACGQLAAKER
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL53_ARATH
Sequence: MESDPNPSAWNQYINPRDCTQGLCSTFCPQWCTYINFSPPPISYEQFLNDGVASNPNLSPLVIAIFGIFATAFLLAAYYTLVSKYCANDTTNEAASESGRSDIILDVNSPERGDQDDPFALESSTAGLDDTLIKKIGFFKLKKHQNGFKINGTDCSICLGEFNEDESLRLLPKCNHTFHVVCIDRWLKSHSNCPLCRAKIIVPTTQQPEHHVVVMNLDRFTSNVGSAEGNVVVDDHREEVSVSISSHHPSWFSAADIVLRISRDGEEEEGNYDLENGNREKLVDLKRSFSSGGLVLGTQGRTRRSLNICP
What are the official names of this protein?
Putative RING-H2 finger protein ATL53, RING-type E3 ubiquitin transferase ATL53.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FOLD_XANC5
Sequence: MTASAPAASASARLLDGRRIAEELLDGLKLRVDARLAAGKARPGLAVVLVGGDPASSVYVRNKRRAAEKVGIEAFDYDLPQGTSEAQLASLIDELNADPKIHGILIQLPLPGIPDANRLIQRIDPRKDVDGFHPQNVGHLALREFGLRPCTPRGIVTLLGHTDQPVRGRNATIVGVSNHVGRPMGLELLIAGCTVTSCHKFTPPDVLEASVRNADILVVAVGRPGLIPGEWVKPGAVVIDVGINRLDDGRLVGDVGFDAAAQRAAWITPVPGGVGPMTVATLMQNTIEAADAAESGDSGLGIG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RN138_HUMAN
Sequence: MAEDLSAATSYTEDDFYCPVCQEVLKTPVRTTACQHVFCRKCFLTAMRESGAHCPLCRGNVTRRERACPERALDLENIMRKFSGSCRCCAKQIKFYRMRHHYKSCKKYQDEYGVSSIIPNFQISQDSVGNSNRSETSTSDNTETYQENTSSSGHPTFKCPLCQESNFTRQRLLDHCNSNHLFQIVPVTCPICVSLPWGDPSQITRNFVSHLNQRHQFDYGEFVNLQLDEETQYQTAVEESFQVNI
What is the function of this protein?
E3 ubiquitin-protein ligase involved in DNA damage response by promoting DNA resection and homologous recombination (PubMed:26502055, PubMed:26502057).  Recruited to sites of double-strand breaks following DNA damage and specifically promotes double-strand break repair via homologous recombination (PubMed:26502055, PubMed:26502057).  Two different, non-exclusive, mechanisms have been proposed.  According to a report, regulates the choice of double-strand break repair by favoring homologous recombination over non-homologous end joining (NHEJ): acts by mediating ubiquitination of XRCC5/Ku80, leading to remove the Ku complex from DNA breaks, thereby promoting homologous recombination (PubMed:26502055).  According to another report, cooperates with UBE2Ds E2 ubiquitin ligases (UBE2D1, UBE2D2, UBE2D3 or UBE2D4) to promote homologous recombination by mediating ubiquitination of RBBP8/CtIP (PubMed:26502057).  Together with NLK, involved in the ubiquitination and degradation of TCF/LEF (PubMed:16714285).  Also exhibits auto-ubiquitination activity in combination with UBE2K (PubMed:16714285).  May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway (PubMed:16714285).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF138, Nemo-like kinase-associated RING finger protein, NLK-associated RING finger protein, hNARF, RING finger protein 138, RING-type E3 ubiquitin transferase RNF138.
What are the subcellular locations of this protein?
Chromosome. Note=Recruited at DNA damage sites (PubMed:26502055). Localizes to sites of double-strand break: localization to double-strand break sites is mediated by the zinc fingers (PubMed:26502055, PubMed:26502057).
Protein: RBL5_ARATH
Sequence: MGKRPPIPPDIENGPPPPARPHFRPPIPVPWVAWLVPLILAANFVTFATTMYVNDCPARSDECLLFDVLGRLSFQPIKENMLLGPSIPTLRKLGALERRLVEEGERWRLISCIWLHGGFLHLMANMISLMCIGMRLEQEFGFMRIGALYVISGLGGSLVSCLTDSQGERVSVGASGALFGLLGAMLSELITNWTIYENKCTALMTLILIIVLNLSVGFLPRVDNSAHFGGFLAGFFLGFVLLLRPQYGYVNPKYIPPGYDMKHKKSKHKCYQHIFRFTSLAILLAGFIAGYTKLLREHTIQSMPFRDFN
What is the function of this protein?
Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.  May function in reproductive organs maturation.
What are the official names of this protein?
RHOMBOID-like protein 5, AtRBL5.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LGT_CLOTE
Sequence: MKPVLFELFGLKIYGYGAMIALGILAAVILLDKRSKKRGYNEDHIFNMAIVGIIGGILGGKLLYIIVDIKNIIDNPEILKDLGNGFVIYGAIIGGAISVYLYCKKKNWDVLKMLDLVVPSVALAQGFGRIGCFLAGCCYGKPTKLPIGVMFTNSPFAPSNIHLHPTQIYSSIFDFLLAFFLLWYSRKAEKSGRVFSLYVIIYGVGRVIVEFLRGDPRGNVSMLSTSQFISLFTIIIGIFVFNIDRFRKQ
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SECA1_MYCBP
Sequence: MLSKLLRLGEGRMVKRLKKVADYVGTLSDDVEKLTDAELRAKTDEFKRRLADQKNPETLDDLLPEAFAVAREAAWRVLDQRPFDVQVMGAAALHLGNVAEMKTGEGKTLTCVLPAYLNALAGNGVHIVTVNDYLAKRDSEWMGRVHRFLGLQVGVILATMTPDERRVAYNADITYGTNNEFGFDYLRDNMAHSLDDLVQRGHHYAIVDEVDSILIDEARTPLIISGPADGASNWYTEFARLAPLMEKDVHYEVDLRKRTVGVHEKGVEFVEDQLGIDNLYEAANSPLVSYLNNALKAKELFSRDKDYIVRDGEVLIVDEFTGRVLIGRRYNEGMHQAIEAKEHVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELHEIYKLGVVSIPTNMPMIREDQSDLIYKTEEAKYIAVVDDVAERYAKGQPVLIGTTSVERSEYLSRQFTKRRIPHNVLNAKYHEQEATIIAVAGRRGGVTVATNMAGRGTDIVLGGNVDFLTDQRLRERGLDPVETPEEYEAAWHSELPIVKEEASKEAKEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDELMRRFNGAALETLLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRKNVLKYDEVMNQQRKVIYAERRRILEGENLKDQALDMVRDVITAYVDGATGEGYAEDWDLDALWTALKTLYPVGITADSLTRKDHEFERDDLTREELLEALLKDAERAYAAREAELEEIAGEGAMRQLERNVLLNVIDRKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQREGYDMFMAMLDGMKEESVGFLFNVTVEAVPAPPVAPAAEPAELAEFAAAAAAAAQQRSAVDGGARERAPSALRAKGVASESPALTYSGPAEDGSAQVQRNGGGAHKTPAGVPAGASRRERREAARRQGRGAKPPKSVKKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: SUH_MOUSE
Sequence: MPSGFPQSPRTSPRARPKTRITGALPMDYSEGLSAEERPAHAPSAGKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEQNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPSNESNTNSEGNYTNASTNSTSVTSSTATVVS
What is the function of this protein?
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations (PubMed:7566092).  Acts as a transcriptional repressor when it is not associated with Notch proteins.  When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes (By similarity) (PubMed:18381292).  Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively.  Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.  Binds specifically to methylated DNA.  Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen) (By similarity).  Negatively regulates the phagocyte oxidative burst in response to bacterial infection by repressing transcription of NADPH oxidase subunits (PubMed:26194095).
What are the official names of this protein?
Recombining binding protein suppressor of hairless, J kappa-recombination signal-binding protein, RBP-J kappa.
What is the protein family that this protein belongs to?
Belongs to the Su(H) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear, upon interaction with RITA1, translocates to the cytoplasm, down-regulating the Notch signaling pathway.
Protein: TOM70_SCHPO
Sequence: MSGISNAENGKAIVSSGVLNSVSAFVRRHRTFVYTIGAVAVFATVGGVYHVQQKKASHKRSKKLKAHQDKAESKVNEGKNEAAKVVKEEDLKSSETGKDVETAAAAAAAAKKKKKNKKKVKAKKVGDSSVDKIATEESVKSMTKEERAKLAAELKTLGNKAYGQKEYANAIDYYTQAITCSHDPIFFSNRAACYAAIGDFEQVIKDTSEALSLDSSYVKALNRRSAAYEQLGKLDEALMDSTVSCIFDGFANESMTATVERLLKKVAEKKSSALLKERPPKLPAASFIQTYLDSFHAQPKPLFDNKFDGDAALAEAYEYLEKGEYQLSYDKAKESCLGSFSSPSVNARTHNLVGTFKFVSGDSKGSMENFNAAIKLDRKFIQPYIRLSAAYLDENDNEKMWKVLNDAESVDKTDSDLYYHRAQVRFVSGEFAEAISDYQKSIALDDSFIYSHIQLGVAQYKTHAIAESMKTFEDCKKRFPNSSEVYNYFGEILLDQQKFDDAVKNFDHAIELEKREHLTIMSAMPLINKALAVFQWKKDISQAENLCRQALSADPECDIAIASMAQFLLQQGKAREALEYFEKSAQLARTESEMVNAFSYAEATRTQIALTEKYPQLVGRLSNPM
What is the function of this protein?
Component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with tom20 and tom22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the tom40 translocation pore.
What are the official names of this protein?
Probable mitochondrial import receptor subunit tom70, Translocase of outer membrane 40 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the Tom70 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: RS18_MYCSS
Sequence: MAKSNKRRPAPEKPVKTRKCVFCSKKGQDIDYKDTALLRTYISERGKIRARRVTGNCVQHQRDIAVAVKNAREVALLPFGSSTR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PYRH_MYCGA
Sequence: MQKPNIIIKISGASLQDKNSNDCYSYQRINSLADQLKSLAKKYNIGLIVGGGNIFRGKLAKDFGVEINKADYIGMLATVINSTLLESKLQSLGLKTKVLSALEVKGLTNEINPKSLAEVFSDCQIAFFSGGTGNSHFTTDTATVLRAIQINAQLVLIGKDGVDGVYTDDPKKNKKAKFIEQITYQQALNDQLRVMDLTAFSLAKDHNLKLLIFNIEAEQSIIKTIENKNKHTKITN
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.