PharMolix/UniProtQA huggingface dataset:
Protein: RL10_BIFLO
Sequence: MKRPEKEAVVAQLTEEFRNADAVYLTEYRGLTVPQISDLREKLGRDTSYTVAKNTLARIAAKEAGIEGLDEILSGPTAITFVKGDFIEAAKVIRDFAKDNKALVIKGAAADGTVYDAEGAKKLADLKSRPQLLAEFAGDIKASMAKAAYLFNALPTKAVRTIDALREKQEKAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: Y293_MYCTU
Sequence: MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAFCRAVGGSWADVLDGKLPDHKLKSTDFGEHFVNFQGARTKYFDEYFRRAAAAGARQVVILAAGLDSRAYRLPWPDGTTVFELDRPQVLDFKREVLASHGAQPRALRREIAVDLRDDWPQALRDSGFDAAAPSAWIAEGLLIYLPATAQERLFTGIDALAGRRSHVAVEDGAPMGPDEYAAKVEEERAAIAEGAEEHPFFQLVYNERCAPAAEWFGERGWTAVATLLNDYLEAVGRPVPGPESEAGPMFARNTLVSAARV
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Rv0281.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: RNAS2_PANTR
Sequence: MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHQSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
What is the function of this protein?
This is a non-secretory ribonuclease.  It is a pyrimidine specific nuclease with a slight preference for U.  Cytotoxin and helminthotoxin.  Possesses a wide variety of biological activities (By similarity).
What are the official names of this protein?
Non-secretory ribonuclease, Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, RNase 2, Ribonuclease US.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Protein: CG24_YEAST
Sequence: MMLEGYTVQPPQSTLIGDIEIQDENANQEVKNVLYQGVQKGIKRLEKRQRRVALGDVTSQKANKIHNAIHNKFHQTKNNFEIENIRSSALVKEQQRDVRHEDSDYFLIDSSEGSSTDDEQVNEDAIDDLLSRRVNDQQIQADEVYEDFDGEMQDVIEEDVDSQIEPLSPINNDEIQTELDRAFEKYFRSVPNPLDDDTHDVVMVVEYASDIFYYLRELEVKYRPNPYYMQNQVELTWPFRRTMIDWLVQLHFRFQLLPETLYLTINIVDRFLSKKTVTLNRFQLVGVSALFIAAKFEEINCPTLDDLVYMLENTYTRDDIIRAEQYMIDTLEFEIGWPGPMPFLRRISKADDYDFEPRTLAKYLLETTIVEPKLVAAAPSWLAAGAYFLSRTILGSNDWSLKHVFYSGYTSSQIIPLASLILENCKNASRRHHSIWKKYFDQKHYRCSQIVEEWIVSTEA
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.  Interacts with the CDC2 protein kinase to form MPF.  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.
What are the official names of this protein?
G2/mitotic-specific cyclin-4.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: Y1647_STRP1
Sequence: MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVDWFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNKEVLSQFRAVDFVKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLLTFDRLNDMSQS
What are the official names of this protein?
UPF0398 protein SPy_1647/M5005_Spy1353.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: OR2A2_HUMAN
Sequence: MEGNQTWITDITLLGFQVGPALAILLCGLFSVFYTLTLLGNGVIFGIICLDSKLHTPMYFFLSHLAIIDMSYASNNVPKMLANLMNQKRTISFVPCIMQTFLYLAFAVTECLILVVMSYDRYVAICHPFQYTVIMSWRVCTILVLTSWSCGFALSLVHEILLLRLPFCGPRDVNHLFCEILSVLKLACADTWVNQVVIFATCVFVLVGPLSLILVSYMHILGAILKIQTKEGRIKAFSTCSSHLCVVGLFFGIAMVVYMVPDSNQREEQEKMLSLFHSVFNPMLNPLIYSLRNAQLKGALHRALQRKRSMRTVYGLCL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2A2, Olfactory receptor 2A17, Olfactory receptor OR7-11.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_ROSCS
Sequence: MHITLIGVHQRNTPVTVRERLAFSLRELPDALLALRRYVEEGIILSTCNRVEVCAVTHDSVGGDAALKSFLAEQRGVDQAVFVPSLYIYHNEAVVRHLYRLAAGLDSMVLGEDQIVGQIKEALAIAHASGAIGPVLHRVLHGALAAGKRARTHTGIASGHVSVVSVAIDALRQHADLLKQGRALVIGAGHMAELTLKHLIAEGCSAITVINRTETRASALAQRYGVAWRPWGDLSDALAMSDMVVSCTSAPGIVVSWQMVERAAVGRSVPLLLFDLAVPRDIDQRVVEIPGVHLYDVDALEPICVTNRAMRAAEAQRAEAIIDGEVAKFMEWWVAQQAVPTIRALRERAEAIRDAEIRRALARCPELSPQQRETVVALSTAIINKLLHEPIVALRDPEAGSELVSAVRRLFNIDDATVHPSAKVT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: BHE41_HUMAN
Sequence: MDEGIPHLQERQLLEHRDFIGLDYSSLYMCKPKRSMKRDDTKDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHLKALTALTEQQHQKIIALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREPRCVQLINHLHAVATQFLPTPQLLTQQVPLSKGTGAPSAAGSAAAPCLERAGQKLEPLAYCVPVIQRTQPSAELAAENDTDTDSGYGGEAEARPDREKGKGAGASRVTIKQEPPGEDSPAPKRMKLDSRGGGSGGGPGGGAAAAAAALLGPDPAAAAALLRPDAALLSSLVAFGGGGGAPFPQPAAAAAPFCLPFCFLSPSAAAAYVQPFLDKSGLEKYLYPAAAAAPFPLLYPGIPAPAAAAAAAAAAAAAAAAFPCLSSVLSPPPEKAGAAAATLLPHEVAPLGAPHPQHPHGRTHLPFAGPREPGNPESSAQEDPSQPGKEAP
What is the function of this protein?
Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes (PubMed:11278948, PubMed:14672706, PubMed:15193144, PubMed:15560782, PubMed:18411297, PubMed:19786558, PubMed:25083013).  Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop).  Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2.  Represses the activity of the circadian transcriptional activator: CLOCK-BMAL1 heterodimer by competing for the binding to E-box elements (5'-CACGTG-3') found within the promoters of its target genes (PubMed:25083013).  Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2.  Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity.  Inhibits HNF1A-mediated transactivation of CYP1A2, CYP2E1 AND CYP3A11 (By similarity).
What are the official names of this protein?
Class E basic helix-loop-helix protein 41, bHLHe41, Class B basic helix-loop-helix protein 3, bHLHb3, Differentially expressed in chondrocytes protein 2, hDEC2, Enhancer-of-split and hairy-related protein 1, SHARP-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS10_LEPCP
Sequence: MQKQKIRIRLKAFDYKLIDQSAQEIVETAKRTGAIVKGPVPLPTRMQRFDILRSPHVNKTSRDQFEMRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RS19_STRPS
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ERCC1_MOUSE
Sequence: MDPGKDEESRPQPSGPPTRRKFVIPLEEEEVPCAGVKPLFRSSRNPTIPATSAHVAPQTYAEYAITQPPGGAGATVPTGSEPAAGENPSQTLKTGAKSNSIIVSPRQRGNPVLKFVRNVPWEFGEVIPDYVLGQSTCALFLSLRYHNLHPDYIHERLQSLGKNFALRVLLVQVDVKDPQQALKELAKMCILADCTLVLAWSAEEAGRYLETYKAYEQKPADLLMEKLEQNFLSRATECLTTVKSVNKTDSQTLLATFGSLEQLFTASREDLALCPGLGPQKARRLFEVLHEPFLKVPR
What is the function of this protein?
Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.  Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL).  Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure.  Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4 (By similarity).
What are the official names of this protein?
DNA excision repair protein ERCC-1.
What is the protein family that this protein belongs to?
Belongs to the ERCC1/RAD10/SWI10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: R212B_PONAB
Sequence: MDWFHCNQCFRKDGAHFFVTSCGHIFCKKCVTLEKCAVCGTACKHLALSDNLKPQEKMFFKSPVETALQYFSHISQVWSFQKKQTDLLIAFYKHRITKLETAMQETQQALVSQDKELSVLRKENGELKKFLAILKESPSRYQGSRSITPRPVAITSPSQSVTPRPSFQHSSKVVSRSSSVESIPYRDAGFGSLGQGGRGLQGRRTPRDSYNETPSPASTHSLSYRPSSASSGQGIFSFRPSPNGHSGHTRVLTPNNFAQRESRTTLESLPSFQLPVLQTPYQQQRQMGLPSGREAWTTSR
What are the official names of this protein?
RING finger protein 212B.
Protein: IRTA_MYCT3
Sequence: MARGFQGVMLRGLGARDHQATVVDKEYIAPHFVRVRLVSPTLFDEVIVEPTSWLRFWFPDPDGSDTEFQRAYTITESDPETGRFAVDMVLHEPAGPASTWARTVEPGATIAVMSMGSRGFSVPEDPEDRPVGYLLIGDSASTPAINGIIEVVPHDIPIELYLEQHHDDDVLIPLAEHPRLRVHRVSRDDASSLAAALELRDWSNWYCWAGPEAGALKQVRTRLRDEFGFPKREVYAQAYWTEGRAMGSSRGETSTPAKPAAKTAPAKAAAKPAAASGAGTPEHAAAPAAATTGAPQAAPAPGAAQPRTPVRGRWRAEAGSRLLAPLKKPLIVSGVLQALITLIELAPFVLLVELARLLLGGAEAERLWTLGLTAVSLIGLGAVLAAAMTLWLHRVDARFAHELRGRLLTKLSRLPLGWFTRRGSASTKQLVQDDTLALHYLITHAIPDAVAAVVAPVAVLVYLFVADWRVALVLFIPVLVYLVLMSVMTIQSGSKIAQAPRWAERMGGEAGAFLEGQPVIRIFGGAAASRFRRRLDDYIDFLVSWQRPFVGKKTLMDLVTRPATFLWIILVAGVPLVVTGRMDPVNLLPFLLLGTTFGARLLGIGYGLSGIQTGMLAARRIQTVLDEPELVVRDRTGQAGTDHASGDQARPGTVELDRVSFEYRPGVPVIRDVTLTLRPGTVTALVGPSGSGKSTLAALVARFHDVTQGAIRVDGRDIRTLTADELYRRVGFVLQDAQLVHGSVAENIALAEPDAGLERIRTAARDAQIHDRITRMPDGYDSVLGAGSALSGGERQRVTIARAILADTPVLVLDEATAFADPESEYLVQQAINRLTRDRTVLVIAHRLHTITHADQIVVLDDGRIVEVGTHDELLAAGGRYRGLWDSGRYSSPDAGRPVSADAVEVGR
What is the function of this protein?
Part of the ABC transporter complex IrtAB involved in the import of iron-bound mycobactin (Fe-MBT) and carboxymycobactin (Fe-cMBT) (PubMed:32296173).  Has a preference for Fe-MBT over Fe-cMBT (PubMed:32296173).  Mycobactins are then reduced by the siderophore interaction domain to facilitate iron release in the bacterial cell (PubMed:32296173).  Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation (PubMed:32296173).
What are the official names of this protein?
Mycobactin import ATP-binding/permease protein IrtA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Siderophore-Fe(3+) uptake transporter (SIUT) (TC 3.A.1.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRAP_STAAM
Sequence: MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPSIYEVIKEIGEFSEHHFYCAIFIPSTEDHAYQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFERYLYPIKE
What is the function of this protein?
Signal transduction protein, which is a major regulator of staphylococcal pathogenesis.  Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors.  Up-regulates the expression of most toxins and genes known to be necessary for biofilm formation (By similarity).
What are the official names of this protein?
Signal transduction protein TRAP, Target of RNAIII-activating protein.
What is the protein family that this protein belongs to?
Belongs to the TRAP family.
What are the subcellular locations of this protein?
Membrane. Note=Membrane-associated.
Protein: RL1_BRUA1
Sequence: MAKISKRINKIREGVDRNKLYDLSAAIGLVKERAVAKFDETVEIAMNLGVDPRHADQMVRGVVNLPNGTGRTVRVAVFARGDKAEEAKKAGADIVGAEELFEIVNGGKIEFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTTDVAAAVAASKGGAVEFRVEKAGIIHAGIGKVSFDNAKLEENIKAFADAVIKAKPSAAKGEYVKRVSISSTMGVGVKVDPSTVKVVD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RLA0_LITSY
Sequence: MPREDRATWKSNYFLKIIQLLDDYPKCFIVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNSALEKLLPHIKGNVGFVFTKEDLAEVRDMLLANKVPASARAGAIAPCDVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFGLIIQQVYDNGSIYSPEVLDITEDALRARFLEGVRNIASVCLQIGYPTVASVPHSVVNGYKRVLALAVETDYSFPLADKVKAFLADPSAFVVAAPVAETAAAPAASAAPAKEEKEESEESDDDMGFGLFD
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0, 60S ribosomal protein L10E.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ERG1_ORYSJ
Sequence: MAGSGVLEVHLVDAKGLTGNDFLGEIGKIDPYVVVQYRSQERKSSVARDQGKNPSWNEVFKFQINSTAATGQHKLFLRLMDHDTFSRDDFLGEATINVTDLISLGMEHGTWEMSESKHRVVLADKTYHGEIRVSLTFTASAKAQDHAEQVGGWAHSFRQ
What is the function of this protein?
May play a role in plant defense signaling (Probable).  Isoform 2 binds to phospholipids in a Ca(2+)-dependent manner in response to pathogen elicitors (PubMed:14529272).
What are the official names of this protein?
Elicitor-responsive protein 1, OsERG1, 17 kDa phloem protein, Fungal elicitor immediate early-responsive gene 1 protein, FIERG1, RPP17.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocates to plasma membrane upon fungal elicitor or calcium treatment.
Protein: FLIW_CLOK5
Sequence: MKLNTKYHGLLEYDEKNIVVFRKGIPGFEHLKKFILVPAEENNLFYILHSIEDENIGIIVASPFDILKDYEFELNEDKTAELKIENMEDIFIVNTVTLNSVLENITINLKAPIVINIKENIGEQLILDKVEYPIKYPLFKGEVSC
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMK2_ARATH
Sequence: MNHLYKNPFRIYEISFHFCASLLLCFLLFSAQAVAGGGGGGHSWDGIVVTQANYQALQAIKHELIDFTGVLKSWNNSASSQVCSGWAGIKCLRGQVVAIQLPWKGLGGTISEKIGQLGSLRKLSLHNNVIAGSVPRSLGYLKSLRGVYLFNNRLSGSIPVSLGNCPLLQNLDLSSNQLTGAIPPSLTESTRLYRLNLSFNSLSGPLPVSVARSYTLTFLDLQHNNLSGSIPDFFVNGSHPLKTLNLDHNRFSGAVPVSLCKHSLLEEVSISHNQLSGSIPRECGGLPHLQSLDFSYNSINGTIPDSFSNLSSLVSLNLESNHLKGPIPDAIDRLHNLTELNLKRNKINGPIPETIGNISGIKKLDLSENNFTGPIPLSLVHLAKLSSFNVSYNTLSGPVPPVLSKKFNSSSFLGNIQLCGYSSSNPCPAPDHHHPLTLSPTSSQEPRKHHHRKLSVKDVILIAIGALLAILLLLCCILLCCLIKKRAALKQKDGKDKTSEKTVSAGVAGTASAGGEMGGKLVHFDGPFVFTADDLLCATAEIMGKSTYGTAYKATLEDGNEVAVKRLREKTTKGVKEFEGEVTALGKIRHQNLLALRAYYLGPKGEKLLVFDYMSKGSLSAFLHARGPETLIPWETRMKIAKGISRGLAHLHSNENMIHENLTASNILLDEQTNAHIADYGLSRLMTAAAATNVIATAGTLGYRAPEFSKIKNASAKTDVYSLGIIILELLTGKSPGEPTNGMDLPQWVASIVKEEWTNEVFDLELMRETQSVGDELLNTLKLALHCVDPSPAARPEANQVVEQLEEIRPETEVETETTPFGSGGEGGKDLGSNEE
What are the official names of this protein?
Probably inactive leucine-rich repeat receptor-like protein kinase IMK2, Protein INFLORESCENCE MERISTEM RECEPTOR-LIKE KINASE 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NIFU_AZOBR
Sequence: MWNYTDKVKEHFFNPKNAGALDEADDVGEVGSITCGDALKLMMKVNPDQPGHRDANFQTFGCGSAIASLRSALTEMIIGKTVDEALGQVTNRDIAEYLGGLPPEKMDCSVMGAEALPAAIANFKGEGLVDDHEEGELVCKCFGIDAAMIERAVTVNSLTTLEEVTHYTKAGGSCQTCHEKIEEVLEAVLAKTGAVGPAQAPSPTPPARSGWTPSSRWPRRPRHAPAKLTNVQRMQKIMFAIEDWRPQIQRDGGDVELVDIDGKDIYVRLTGACSGCSQSAGTMMGVQAKLVEALGEFVRVKPASLLPVGA
What is the function of this protein?
May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
What are the official names of this protein?
Nitrogen fixation protein NifU.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
Protein: AUR32_RANAE
Sequence: GLFDIVKKIAGHIASSI
What is the function of this protein?
Has antimicrobial activity against L. lactis, L. innocua, M. luteus, S. aureus, S. epidermidis and S. uberis.  Probably acts by disturbing membrane functions with its amphipathic structure.  Shows anticancer activity.
What are the official names of this protein?
Aurein-3.2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Aurein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYT_SALEP
Sequence: MPVITLPDGSQRHYDHPVSPMDVALDIGPGLAKATIAGRVNGELVDASDLIENDATLAIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVVDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHDARETFVKRGETYKVAILDENIAHDDKPGLYHHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHIFCTEEQIRDEVNACIRMVYDMYSTFGFEKIVVKLSTRPDKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVVMNITDSQSEYVNELTQKLQNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVEAGKVAVRTRRGKDLGSLDVNDVIEKLQQEIRSRSLQQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_YERPY
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEVTTNAWVDIEEITRRTIREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRENPLEQGAGDQGLMFGYATNETSVLMPAPITYAHRLVERQAEVRKNGALPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEDINQKDLHEAVMEEIIKPVLPAEWITAHTKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVEAFGTEKIPADQLTLLVREFFDLRPYGLIKMLDLLHPIYRETAAYGHFGREHFPWEKTDKAALLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_DESAH
Sequence: MTYPGILLKKQQLMARKELGQNFLSDPNAARMIVTKAGISDQDRVLEIGPGLGALTIPAAKLARDLVAVEKDTRLAGILMEELKRESIENVELINNDILHQDLNTLFRGEKIIVIGNLPYNISSQVLFMLVENRHLIKRAVLMFQKELTERISASPGGRDYGRLSVVMQYCSTVKKIADLPPHLFFPKPAVDSRVIEVNFFETTPYSGERERFLFKVIKAAFSKRRKTLRNSLAGGELDIDTKVSAKILETAEIDPVRRAETLSVEEYSRLSDALWSMHGSEEV
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_SALDC
Sequence: MSVSAFNRRWAAVILEALTRHGVRHVCIAPGSRSTPLTLAAAENPAFIHHTHFDERGLGHLALGLAKVSQQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQAGMFASHPSQTLSLPRPTQDIPARWLVSTIDNALAMLHAGALHINCPFAEPLYGDMNDTGLVWQQRLGDWWQDEKPWLREARRLASDKQRDWFFWRQKRGVVVAGRMSAEEGKKVAQWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKAVTELQQAQIVVQLGSSLTGKRLLQWQATCEPEEYWVIDNIEGRLDPAHHRGRRLVAKIADWLEMHPAEKRKPWCVEIPRLAELAWQRVVAQRDTFGEAQLAHRIRDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASAKSTLAIVGDLSALYDLNALALLRQVSAPFVLIVVNNNGGQIFSLLPTPQSKRERFYLMPQNVHFDHAAAMFNLRYHRPENWEELESALAGAWRTPATTVIELVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RR18_GUITH
Sequence: MAIFRRKNSPIKKDDFIDYKDVELLSKFLTEQGKILPRRITGLTMKQQSRLTKAVKRARILSLLPFINRDMIL
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSUG_RHILO
Sequence: MSPETARPFIDIHAPVAQALAAGRPVVALESTIITHGMPYPDNGAMAANVEKIISDGGAVPATIAVIGGRIKIGLSDGERESLAMTGDAMKLSRADLGFAVAQGRTGGTTVAATMIAAEMVGIKVFATGGIGGVHKGAEKSFDISADLDELARTPVIVVSAGAKAILDIEKTLEVLETRGVPVVGHGCETMPAFWSRQSPFRAPLTLYKPEEIAHFFRTRVALGLGGGVLVANPVPENHEIPAEEMAGYIEAAQKAAEALNVTGKAVTPFLLGKILELTGGRSLKTNIALVENNARLAAEIAKAL
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: CWLA_BACSU
Sequence: MAIKVVKNLVSKSKYGLKCPNPMKAEYITIHNTANDASAANEISYMKNNSSSTSFHFAVDDKQVIQGIPTNRNAWHTGDGTNGTGNRKSIGVEICYSKSGGVRYKAAEKLAIKFVAQLLKERGWGIDRVRKHQDWNGKYCPHRILSEGRWIQVKTAIEAELKKLGGKTNSSKASVAKKKTTNTSSKKTSYALPSGIFKVKSPMMRGEKVTQIQKALAALYFYPDKGAKNNGIDGVYGPKTADAIRRFQSMYGLTQDGIYGPKTKAKLEALLK
What is the function of this protein?
Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation.
What are the official names of this protein?
N-acetylmuramoyl-L-alanine amidase CwlA, Autolysin, Cell wall hydrolase.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
Protein: H2A17_CYRHA
Sequence: MKVTLIAILTCAAALVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Neurotoxin active on both insects and mammals.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II.17, HNTX-II.17, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.