PharMolix/UniProtQA huggingface dataset:
Protein: RS18_MALP2
Sequence: MEKKTTKKATASKTTTTKKAAAEKTEIKETKKTTTTKTSTAKKATTASVEKTEVKETKKSSDNKKEFNPQDRPFAKYNRGYPNKQGRRKKFCKLCAKGQEHVDYKDVELLYKYLTPNLKIASRKITFACSKHQTRVSNAIKRARIVALIPFVRD
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: YL872_MIMIV
Sequence: MEYKLNKYIHKINTDPKSIYLNKIAKYYDSSIPIQVGGLRLNDFDSLVKFLKQAYDKAPTETSNKYLVILYGPPASGKSISRYIASYWIQELFKETESIENIYKSFIDTGIDEITYDIETPTGKRIIDLLKENIDNKLGNDKSIENAKKNISLLASSSWDIYRTNRPDYVSELLYYFAIFLNKNIFLETTGSSIPYLERIINLLSFYGYIPIVVYPFINDVSILYNRSIQRGLKEGRFLRCDTSFGLASQMQISLANYPKIKNIVSQYKNYLIYQYNSNFSNEITKNIYSFNFSSLGDYMLEFKCKIETIDDKITQNNIIDITSNNYDKALNLNLNCGEN
What are the official names of this protein?
Uncharacterized protein L872.
What are the subcellular locations of this protein?
Virion.
Protein: MED4_CHAGB
Sequence: METNLDGCFERVEKTLGSMIDSLAKNNPSQKLAEELLAAEAELSKSLKLLETHQNNNARLQQLRQETSLHDTQLKDIMSSLWNMRRELKAVPTTSNPPPGPKHQFTTSELLAYARRISRNTLPLPGVTNGVDMTPTQFSASLTEPEDSFRLQFQPTQTQTPTNSFNLSFNGTVSTPIGLSAPTPTTTNDTQPSTQLPPSQQPPPKTAPADDKLPAHLKPAVNPLHDAAFHPWPTEGQIRTGALAALQRLVDAGIEPRGYDPAEQERRRVAEEKARREAEERARLEREEAERKGREERERMAREREAARLRNAGGADGDGERRESVAVARPKPKQFTFLGADDDEDDEDEDD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 4, Mediator complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYR_IGNH4
Sequence: MYVLSETKSNFLKLIAEALKRRGLEVEEEELERLAGRPPSPEMGDLGVSLFRYAKKLGLRPEELTSELKGEIEGRLAGVKEVKAIGGFLNVELEPSWLAERALREASREDYGKWSFSGRLVVEHTSANPVHPLHVGHARNMFLGDSLVRILKNWGADVQSRFYINDMGRQVAVLVYGLLKLGRLEPPEGEKPDHWYGKVYSVANALVELNSPSKGDDEKKEWEEVLKELESKWPEIVREMKEKFDDEDPEAKVSELMKKYEEGDPEVKETFRKVVNEVLKGFKETMERVGVNVDKWDWESDLVWSGEVDKIINMAKEKGLVIEKDGALVMVFKNLNDEVRRRLRIPKGLQIPPLVLKRSDGTTLYTTRDIAYTIKKFEEFRADRVINVIAAEQRLPQIQLRLALWELGFKEYAENLIHYAYEMVNVPGMKMSGRRGRMITLDWLLDEAERRVRELVEGRSEAEDVDEVVKKVAVGAVKFAMVSVSPEKPITFKWEEVLNFERNSAPYLQYTYARAVGILRKGGEPDLERADYSKAEKYKDMILSIAEFPEVARKAAEDLKPDLIATYLLSLADKFNEFYHKEPVAKEPDEGLRNLKLALVKAVANTIRRGLWLLGVEAPARM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y879_MYCTO
Sequence: MSVENSQIREPPPLPPVLLEVWPVIAVGALAWLVAAVAAFVVPGLASWRPVTVAGLATGLLGTTIFVWQLAAARRGARGAQAGLETYLDPK
What are the official names of this protein?
Uncharacterized protein MT0902.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMM_LISMC
Sequence: MEKMYNVGKIVNTHGLIGEIRVIATTDFPEERFQVGNTVYLFEKNSKKPEKLIIRSHRKHKNFDLLMFEGFTGIHQVERMKEGVLKIKEAQLTDLEENEFYFHEIIGCIVVTTDGKELGEITEILTPGANDVWVVKGSDKKEKLIPYIADVVKEININDKKITIEVMEGLLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_NITEC
Sequence: METSVVLRSVRLSAQKGRLVVNQIRGLQVDQAIKLLTFSPKKGAVIILKLLESAVANAEHNEGADIDELKVARVFIGQGSSLKRVSPRAKGRGNRISKPTCNIFLTVCNR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: COBM_RHOER
Sequence: MTVYFIGAGPGAADLITVRAQRIIAASPVCLYAGSLVPQELLAECPEGARVIDTARLSLDEIVALLIEADAAGQDVARLHSGDPSIFSAVAEQVRRLESAGVAYQVVPGVPAFTAAAASLGRELTVPGVSQSIVLTRVSTLSTAMPEGEDLRSLGRSGATMVVHLGAHRIDQIAEELIEDYGRDCPAAVVAFASRPDEIVLRGTLATIADQVKAAGVTKTAVVIVGRVLAAEGFPDSYLYSATRERTTH
What is the function of this protein?
Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5.
What are the official names of this protein?
Precorrin-4 C(11)-methyltransferase, Precorrin-3 methylase.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: SYY_METTH
Sequence: MDDSLKTITRDVLEVITPEELMDVLKKDEPVVYTGYEPSGRIHLGHALTVRKLRELQDAGFRVKILLADYHAYLNGKGSMERIRELADYNQKCFLALGLSPERTEFILGSSFQTEPEYTDLVYRLALITTLLRAKRSMAQITRESRDHKVAEVIYPLMQVIDMVYLGVDVALGGMEQRKIHMLARENLPRLGFDAPVCIHTPLLHGTDGSEKMSSSKGNFIAVDDSPDEIREKVKKSYCPMGETEGNPIIEIVKYFIMPEYGMMTIRRPEKFGGDLELELDELLEMYSSSELHPLDLKNAVSDYLVDMLEPVREYMEGV
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_RICPU
Sequence: MNKLIPLPREFFARDTNVVSTELIGKTLYFQGKTAIITETESYIGQNDPACHAARGRTKRTDIMFGPAGFSYVYLIYGMYYCLNFVTEAKGFPAATLIRGVHVISPENLYLNGPGKLCKYLGINISHNKCDLINNNAFFVGDIGLKLPYSTTARIGITKGTDKLWRYVVTDITNLISQYNVQP
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RHAA_ECO8A
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRTDLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPTGSEWLESVRAYEKAILSQRG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAC1_CARRO
Sequence: KWCFRVCYRGICYRRCR
What is the function of this protein?
Significantly inhibits the growth of Gram-negative and Gram-positive bacteria.
What are the official names of this protein?
Tachyplesin-1, Tachyplesin I.
What is the protein family that this protein belongs to?
Belongs to the tachyplesin/polyphemusin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAMT2_PETHY
Sequence: MANNGENGRHQEVGHKSLLQSDALYQYILDTSVYPREPEPMKELREITAKHPWNIMTTSADEGQFLSMLIKLINAKNTMEIGVFTGYSSLATAMALPDDGKILAMDINRENYEIGLPVIEKAGLAHKIEFKEGPALPVLDQMIEDGKYHGSYDFIFVDADKDNYLNYHKRLIDLVKVGGLIGYDNTLWNGSVVAPPDAPLRKYVRYYRDFVLELNKALAADPRIEICQLPVGDGITLCRRIS
What is the function of this protein?
Involved in the production of floral volatile phenylpropanoids in flowers of fragrant cultivars (e. g.  cv.  Mitchell and cv.  V26) from cinnamic acid, a common precursor with the anthocyanin biosynthesis pathway involved in flower pigmentation (By similarity).  Methylates caffeoyl-CoA to feruloyl-CoA, also able to methylate 5-hydroxyferuloyl-CoA (PubMed:26620524).
What are the official names of this protein?
Caffeoyl-CoA O-methyltransferase 2, PhCCoAOMT2, 5-hydroxyferuloyl-CoA O-methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CDC61_ARCFU
Sequence: MNIFDNILSSATIFKNRDVLRHSYTPEKLPHREEQINQLALLLSPMLRGGTPSNIFIYGKTGTGKTATVLFVARQLEEASRKAKLNVAVHYINCEIVDTAYRVLASLARKFGSNVPMTGWPTDQVYEEVKKALERRGTRVVVILDEIDKLVKKAEEALYGLTRINSELENSSICIVGISNNLKFKEYLDARILSSLSEEEIVFPPYNAEQLEDILQQRAKLAFEDGVLEDGVIQLCAAIAAQEHGDARKALDLLRVSAEIAERERDSMVRVEHVKKAVRKIETDYMIETVRTLPVHSKILLYSMSLISENSPKFTTGEVYCVYKKLCGKVGVDPLTQRRISDLISELDMLGILNSVVISKGRYGRTREMKLEADEKVLRKALEEDYRLQNLRKFEGELKKLANLNLFQF
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 1.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: RL22_STAA9
Sequence: MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTNKASSPVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSDGKEEAKEA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: NUOC_DECAR
Sequence: MSAKLETLSQNLQEHFGDKLKSLKLALGEITIEVAAADYFCVMTALRDEAAFGFEEMIDLCGVDYSTYGDGTWQGARFAVVVHLLSVANNWRLRVRVFAEDEGFPSVASITTVWASANWFEREAFDLYGIAFVGHDDLRRILTDYGFIGHPFRKDFPISGHVEMRYDPDQARVIYQPVTIEPRENTPRIVREDTFGDTAHG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARGR_LACLS
Sequence: MKRDKRLEIIKEIVTNNKISTQEELQSLLLERGVEVTQATLSRDIRKLNIIKKRDKGESFYSFLTSGNSKINSDLQLYFYNFVISAKSVGALVVIRTKLGEADVLANALDDERDSRTDILGTIAGADTLLVICASEKAANILTAEIKYILLG
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_ROSDO
Sequence: MGIQAAEISAILKDQIKNFGQEAEVAEVGRVLSVGDGIARVYGLDNVQAGEMVEFPGGIQGMALNLESDNVGVVIFGSDRDIKEGDTVKRTNSIVSVPTGDELLGRVVDGLGNPIDGKGPIKTKTTSVADVKAPGIIPRKSVHEPMATGLKAVDSMIPIGRGQRELIIGDRQTGKTAVALDAILNQKSYNDAAGDDESKKLYCVYVAIGQKRSTVAQLVKKLEETGAINYSIVVAATASEPAPMQFLAPYSATAMAEHFRDNGRHALIVYDDLSKQAVSYRQMSLLLRRPPGREAYPGDVFYLHSRLLERSAKLGDDAGNGSLTALPIIETQGGDVSAFIPTNVISITDGQIFLETELFYQGIRPAVNTGLSVSRVGSSAQTSAMSSVAGPVKLSLAQYREMAAFAQFGSDLDASTQQLLARGARLTELMKQPQYSPLTNAEIVCVIFAGTNGFLDKVDVKDVGRFEEALLNHMRSKHSDVLDWITNEDPKIKGDAADKLKAAISEFASDFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NIRF_PSEAE
Sequence: MNLRPLAPLLLTLLAGCSQQPPLRGSGDLGVLIERADGSVQILDGTAKTSLARVEGLGDLSHASLVFSRDQRYAYVFGRDGGLTKLDLLAQRIDKRLIQGGNSIGGAISQDGRLVAVSNYEPGGVKVFDSRTLELVAEIPATRLPGQDRNSRVVGLVDAPGQRFVFSLFDSGEIWIADFSQGDTPHLTRFRDIGKQPYDALISPDGRYYMAGLFGEDGMAQLDLWHPERGVRRVLGDYGRGQRKLPVYKMPHLEGWTIASDQAFVPAVGHHQVLVLDARDWKQTDAIDVAGQPVFVMTRPDDRQIWVNFAYPDNDKVQVIDSETHEVIETLRPGPGVLHMEFSGRGDQVWISVRDADQLQVWDPYRLKRIGSLPARSPSGIFFSHRAQHIGL
What is the function of this protein?
Required for the biosynthesis of heme d1 of nitrite reductase.  Could have a dehydrogenase activity yielding sirohydrochlorin from precorrin-2 or dehydrogenation of propionate side chain C17.
What are the official names of this protein?
Protein NirF.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_MESH7
Sequence: MTMNLINKKNLNIYLCGPTVYSDVHIGNLRTIIIFDAIFECLKNKGFSINFLHNITDIDDKIIEKAQELGISEAELTEKYTNEYFKILEIFNIKKPTKIVRVTEKIEKIIEYIKLLEKKGFTYYNKNNDLVFDILKIPNYGIISGQKIESLLDKNTKKTKSNNDFVLWKKTQKGLFFKSLFGLGRPGWHTECAALIYDYFQKKSLDLHGGGVDLIFPHHENENAQHFALTGNPIAENWFRSGFVNLNGKKMAKSLNNVLLAKDFSHKYNPDIIRSIFLSINPTVPINLTEELIKNHKKLIEKYQKICFEWYFDKKNEKTEKVEQVLNLFIEGKFAKANFLIMELIKQKENSTIRKIFLNLRFNFTKMRLDPESQEKIKNWNKLIMDKNYSEADKIREELWKIFKNS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP46_CRYNB
Sequence: MSTSLETPSGTSAGPSIVASGLPPLADLVRAGSKRTRVVYGAETSAVEDDGLARANKIKLATKLAIEYKDVQTLPPILQAQQTGPAGPKRPTQPSIAASATAGPNVKLIGGPEAEKASSSTPQAVAEPRSLVKFRHQEGFAAEGGQATSRLSQALMRKKEAREVKPEYHPEWKLTRVISGHMGWVRAVAMDPGSQWFATGAGDRVIKIWDLASGELKLSLTGHISTIRGLAVSDRHPYLFSCAEDKMVKCWDLETNKVIRHYHGHFSGVYSLSVHPTLDVLVTGGRDASVRVWDMRTRANIFTLTGHTSTVGDVKTQDSDPQIISGSMDSTVRLWDLAAGKCMNTLTHHKKSVRALAIHPTEYSFASASSGGNNIKKWKCPEGIFVNNFVGHEAIINTLSINSENVLFSGADNGTLTLWDYKTGLPFQHLKDIPQPGSLDAEAGVFCSTFDKTGTRLITGGADKTIKVYSEQA
What is the function of this protein?
Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
What are the official names of this protein?
Pre-mRNA-splicing factor PRP46, Pre-mRNA-processing protein 46.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRL1/PRL2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: P6_TNVA
Sequence: MAACRCCDTSPGITLFPYFAILILILAILVVGTPNQQYHHSPSTYEYKTQHISIAK
What are the official names of this protein?
Uncharacterized protein p6.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TREA_SALTI
Sequence: MIPPEIRRSVLLQKAIKLALAGTLLTFASFSATAADPSSDTETPQPPDILLGPLFNDVQNAKLFPDQKTFADAIPNSDPLMILADYRMQRNQSGFDLRHFVDVNFTLPKAGEKYVPPAGQSLREHIDGLWPVLTRSTKNVEKWDSLLPLPESYVVPGGRFREIYYWDSYFTMLGLAESGHWDKVADMVANFGYEIDAWGYIPNGNRTYYLSRSQPPFFAFMVELLVQHEGDDALKEYLPQLQKEYAYWMEGVETLQPGQQNQRVVKLEDGSVLNRYWDDRDTPRPESWVEDIATAKSNPSRPATEIYRDLRSAAASGWDFSSRWMDNPQQLSTIRTTTIVPVDLNALLYQLEKTLARASAAAGDRAKASQYDALANARQKAIEMHLWNNKEGWYADYDLQNNKIRDQLTAAALFPLYVNAAAKDRAAKVAAAAQAHLLQPGGLATTSVKSGQQWDAPNGWAPLQWVAAEGLQNYGQDDVAMEVTWRFLTNVQHTYDREKKLVEKYDVSSTGTGGGGGEYPLQDGFGWSNGVTLKMLDLICPQEKPCDSVPSTRPASLSATPTKTPSAATQ
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Putative periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NEUR3_RAT
Sequence: MEEVSSCSLRSTLFQQEEQNRITYRIPALLYIPPTHTFLAFAEMRTSSRDEDAVYLVFRRGVMKGCSVEWGPQQPLMEATLPGHRTMSPCPVWEKNTGRVYLFFICVQGHVSERWQLLWGRNAARLCFLYSEDSGCSWGEVKDLTEEVVGSEMKHWATFAVGPGHGIQLQSGRLLIPAYAYLISCWFLCFPCSVKPHSLMFYSDDLGVTWHCGKFIKPQVTGECQVAEVPGKAGNLVLYCSARTPNKFRAEAFSTDSGDCFQKPTLNQQLCEPRGGCQGSVVSTRPLKMPYTCQDSSGKDVPSTQKCPLMDRSLEVEEGAGAPSGTWLLYSHPTNKKKRMNLGIYYNQNPLEVNYWSRPWILNRGPSGYSDLAVVEGQGLFACLFECGERHEDEKIDFCLFSDQEVLSCDDCTSPSSN
What is the function of this protein?
Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides.  Displays high catalytic efficiency for gangliosides including alpha-(2->3)-sialylated GD1a and GM3 and alpha-(2->8)-sialylated GD3.  Plays a role in the regulation of transmembrane signaling through the modulation of ganglioside content of the lipid bilayer and by direct interaction with signaling receptors, such as EGFR.  Desialylates EGFR and activates downstream signaling in proliferating cells.  Contributes to clathrin-mediated endocytosis by regulating sorting of endocytosed receptors to early and recycling endosomes.
What are the official names of this protein?
Sialidase-3, Ganglioside sialidase, Membrane sialidase, N-acetyl-alpha-neuraminidase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Membrane, caveola. Early endosome membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Note=Associates with the external leaflet of the plasma membrane (By similarity). S-acylated NEU3 likely spans the lipid bilayer with a portion of C-terminus exposed to cytosol and the catalytic region facing the extracellular space (By similarity).
Protein: METXA_CYCMS
Sequence: MNLQSPHLTIEMTQEIFYCQEALSLESGESFPEFQLSFTTQGQLNANKDNVIWVLHALTGDANPHEWWSGLIGEDKFFDPSKYFIVCANFLGSCYGSTQPLSNNPNNGKPYYYDFPNITTRDIASALDKLRIHLGLEKINTVIGGSLGGQVGLEWAVSLGEKLENAIIVASNAKASPWIIGFNETQRMAIESDSTWGKTQPEAGKKGLETARAIGMLSYRHPMTFLQNQSETEEKRDDFKISSYLRYQGLKLANRFNAMSYWILSKAMDSHDIGRGRGGTPVALSNIKCKVLSIGVDTDILFTSEESRYISKHVPKGTYREISSIYGHDAFLIEYEQLQYILKSFYLENNG
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIT_SALTY
Sequence: MTSTVEFINRWQRIALLSQSLLELAQRGEWDLLLQQEVSYLQSIETVMEKQTPPGITRSIQDMVAGYIKQTLDNEQLLKGLLQQRLDELSSLIGQSTRQKSLNNAYGRLSGMLLVPDAPGAS
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GATB_DESVV
Sequence: MASYEAVIGLEVHAQLRTRSKLFCSCSTAFGADPNAHVCEVCAGMPGVLPVLNEKAVEFAARMGIAVGCTVNRTSVFARKNYFYPDLPKGYQISQYEQPICEHGHLDISVGDAVKRIGITRIHLEDDAGKNIHSAGENVSYVDLNRTGVPLIEIVSEPDLRSAEEAVAYLKALRAIVVHLGICDGNMEEGSFRCDANVSLRPRGAAEFGTRAELKNLNSFRHVQRAIEYEISRQADLLDDGDKVVQETRLYDSVKNITVSMRGKEEAHDYRYFPDPDLIPIHIDEARLAEWQATLPELPQARLERFMSSFGLSAQDAEVLTAERDHAEFFEAAVKLYDQPRKIANMMLGPLQRELNQRGTSLAVSAMRPEALAELVRIIDAGLISAKIGNDVFGELFENGAMPEAFVRERGLVQISDTSAIEQAVDEVIAENPAEVEAYRGGKTKLVSFFVGQVMRKTRGKANPALVNELLASKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: MURC_BIFLO
Sequence: MSQDQPIVLDPTYASFDAAARPADLGATHFIGIGGAGMSVLAEMLHAEGVAVDGSDRAHSAKTDRLETLGITVEFGQRAENVAQAETVVYSSAIKPDNPEIVAAHAAGKRIVHRSDILALLMNGKRAVTVAGAHGKTTTSSMLSHILVNAGADPSYAIGGFIQGPDGTTLDGGHAGKGDILVAEADESDGSFAKYHPTIAIITNCEADHLDHYGDEAHYRAAFVAHAGRATGHVIISIDDPDGLAVLEALPADVKSHTVAYGTTARESLPDLGGAAYVWIASESETAGSGVEQLTLHLPAAVTAGEPVSQSVALKVPGVHNARNAAAAISAAVLLGVSPADAAKAAGTFLGAARRFQVRGTVKQVTVVDDYAHHPTEIAALLDAARRRYPDSTIRVIFQPHLFSRTKFFAHQFAKSLAKADDVIITGIFPAREKQADFPDISPSTIVDAAAGLKDASAGTWIQPVEDMCLAAKMMAMRAHHGDVIFTVGAGDITDMDQVLLTALEAHRESCE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPAC_BURMA
Sequence: MNRIFKSIWCEQTRTWVAASEHAVARGGRASSVVASAGGLEKVLKLSILGAASLIAMGVVGPFAEEAMAANNAGVCLTYNGSSNNTSGTGGWFADGCKSAGWVQGMVTNSKTDWVGLTADDTQIVLDGSAGSIYFRTGGINGNVLTMSNATGGVLLSGLAAGVNPTDAVNMSQLTSLSTSTATGITSLSTSTATSIASLSTSMLSLGVGVVTQDASSGAISVGANSPGLTVDFAGGQGPRTLTGVAAGVNATDAVNVGQLASLSTSTAAGLSTAASGVASLSTSLLGAAGDLASLSTSASTGLATADSGIASLSTSLLGTADNVTSLSTSLSTVNANLAGLQTSVDNVVSYDDPSKSAITLGGAGVATPVLLTNVAAGKIAATSTDAVNGSQLYTLQQEFSQQYDLLTSQVSSLSTSVSGLQGSVSANTGTASGDNSTASGDNATASGTNSTANGTNSTASGDNSTASGTNASASGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASATGENSTATGTDSTASGSNSTANGTNSTASGDSSTASGTNASATGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASATGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASATGENSTATGTDSTASGSNSTANGANSTASGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASATGENSTATGTASTASGSNSTANGANSTASGAGATATGENAAATGAGATATGNNASASGTSSTAGGANAIASGENSTANGANSTASGNGSSAFGESAAAAGDGSTALGANAVASGVGSVATGAGSVASGANSSAYGTGSNATGAGSVAIGQGATASGSNSVALGTGSVASEDNTVSVGSAGSERRITNVAAGVNATDAVNVGQLNSAVSGIRNQMDGMQGQIDTLARDAYSGIAAATALTMIPDVDPGKTLAVGIGTANFKGYQASALGATARITQNLKVKTGVSYSGSNYVWGAGMSYQW
What is the function of this protein?
Involved in virulence.  Mediates adherence to human respiratory epithelial cells.
What are the official names of this protein?
Autotransporter adhesin BpaC, Type 5 secretion system autotransporter BpaC.
What is the protein family that this protein belongs to?
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
What are the subcellular locations of this protein?
Cell surface. Cell outer membrane. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface.
Protein: YFJF_SALTI
Sequence: MPDKLVVEVAYALPEKQYLQRVTLEEGATVEEAIRASGLLELRTDIDLAKNKVGIYSRPVKLTDTVQDGDRVEIYRPLIADPKALRRQRAEKSAGR
What are the official names of this protein?
UPF0125 protein YfjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.