PharMolix/UniProtQA huggingface dataset:
Protein: THNS2_MOUSE
Sequence: MWYTSTRGMAPRVNFEGALFSGYAPDGGLYMPEELPRLDEETLRHWSTLSYRSLVKELCALFIGLELIPRHDLNDLIDRAFSRFRHRNVVHLCKLKNGLNILELWHGVTYAFKDLSLSCTAQFLQYFLEKKKKHVTIVVGTSGDTGSAAIESVQGSKNVDIIVLLPKGHCSKIQELQMTTVLKENVHVFEVEGNSDELDEPIKAVFADVAFVQRHNVMSLNSINWSRVLVQMAHHFFAYFQCTPSLDTHPLPTVEVVVPTGAGGNLAAGCIAQKMGLPICLVVAVNRNDIIHRTVQKGDFSLCEVLRTTLASAMDIQVPYNMERIFWLLSGSDSQTTRALMEQFERTQSLQLPKDLHNKLSEAVTSESVTDEAITQTMARCWEENQYLLCPHSATAVNYHYQQTDSGQSSIRCCLASASAVKFPEAVQAAGLTPETPAEILALEHKETRCIPMRRGDDWTQMLRVTIEGLSQRWKDCVVNPSE
What is the function of this protein?
Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates.  Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate.  Also degrades O-phospho-homoserine (PHS), but this is not its physiological substrate.
What are the official names of this protein?
Threonine synthase-like 2, TSH2, mTSH2.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: ATPH_STAPU
Sequence: MNPVISAASVIAAGLAVGLASIGPGIGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MAF1_CANGA
Sequence: MKFIDELDIERVNQVLNFETIDCKIVGGCDIFTTKAVASDRKLYKTIDHHLDTILQDNESYNLALQQQIALDAEDKNERSMSPGGQRRDSSSFWEQKRRMSVSDSPIYLQHINGNLNESNGAQGEIVADLVPPIIKTSKLNDHNLKELVSNYEAGYSSSSSVESLTHKNKERRTSSLSSTGGKVDKLRADSSTANDITARSVLNDTSRTLNLGPFGPINEPSSRRTFAYLIAILNASYPDHDFSLLEPTDFKRSSIKSFIAKFENSMYSLGRKPEEWIWEVINSHMTLSDCVLYQYCPTQSFLDDEPGHLWSLIGFFFNKKRKRVAYVYLLASRLQLAVNNAIGTPDEMQNEDGTFRNNNTTSFDNNNTQFEGEYDLTYEENAIVDDDDEE
What is the function of this protein?
Mediator of diverse signals that repress RNA polymerase III transcription.  Inhibits the de novo assembly of TFIIIB onto DNA (By similarity).
What are the official names of this protein?
Repressor of RNA polymerase III transcription MAF1.
What is the protein family that this protein belongs to?
Belongs to the MAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPPP_ECOK1
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MVP_PEMVC
Sequence: MATSVIQFGSFVCNLPKSQPLCTTVHCPKQSMSTNIVRPSDPFAELEKHLEPYLQKRMDATIRQTKGGTLVYKHMSEAKRARKLRKKQREEEEVRLFMNAAPYIVSNITIGGGEVPSKMEEVSIKRPLNKTPSRKIKKSLTPVTFRDGHMNKFLRELRDCATRNSMTVHLIGKRKTELAFKRRASLNAVYATLHHMRGVDRKRDIVLEEWMNDYVLNLSKVSTWGSLFHAESLKRGDSGLILNARALRGKFGRCSRGFFIVRGKSDGVVLDARSKLSMATVTHMEQYSTPEAFWSGLEKKWSVVRKPTAHTCKPTYSVSNCGEVAAIIAQALFPCHKLTCGECSKEICDLTSNECVQELYKNTSLALERMNNLHPEFQHIVKVLSVVRQLTEASNHGTETFDEIFKMIGSKTQSPFTHLNKLNEFMLKGNENTSGEWLTARQHLRELVRFQKNRTDNIKKGDLASFRNKLSARAQYNLYLSCDNQLDKNASFLWGQREYHARRFFLNFFQQIDPSKGYLAYEDRTIPNGSRKLAIGNLIVPLDLAEFRKRMNGIDTQQPPIGKYCTSQLDGNFVYPCCCTTLDDGQPIRSAVYAPTKKHLVVGNTGDTKYINLPKGDTEMLYIALDGYCYINIYLAMLVNISEEEAKDFTKKVRDIFMPKLGKWPTLMDLATTCAQLRIFHPDVHDAELPRILVDHNTQTCHVVDSYGSISTGYHILKAATVSQLVLFADDNLESEIKHYRVGGIVENHKVQIDNQPSRCGVSEFHAIRMLIKGIYRPSVMYELLSEEPYLLVFSILSPSILIAMYNDRAFELAVQIWLEKEQSIPLIATILTNLAAKVSVATTLVQQLQLIELSADQLLNVTCDGFRVSFAYQSALTLLTRMRDQAKANSELISGGFNEYDQDLAWTLEKKLSRPLTRPMERIKLAGKISLLLVLKKAKDSFAVKYQKQKFARCQRNIQFITETIYGKGFLPHESRSSVHQARN
What is the function of this protein?
Allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding (By similarity).
What are the official names of this protein?
P3N-PIPO polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae P3N-PIPO polyprotein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma.
Protein: UPP_CALS4
Sequence: MYENVFVIDHPLIQHKISLIRDENTGSKEFRELVGEIAMLMAYEVTRDLPLEEIEVKTPIAVAKTKVIAGKKLGIIPILRAGLVMADGMLKLIPTAKVGHIGIYRDPETLKPVEYYCKLPSDIAERDLIVVDPMLATGGSASAAIHFLKERGAQSIKLVNLIAAPEGIKAVHKDHPEVPIYVASIDQGLNEHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: N4BP1_CHICK
Sequence: MAARWAAHGPGPGLDEFTVPAEKRRFLEGSRGRIQGLFEVRLAVLEAQGDWRPALPPPGQPPPAARIWVQLAGGGKAVRSAKEYIKGLCEPELEEKEYYPKDMHCIFVGAQNMFLNSLIQDTCADITVLEIGLLSIKGGAEAVVMAQSQVQQFVKLFENNESLSSECESDIKKQFRQFVEAHADKYTMDLLILPSSLKRELLTLMQTECCESRGAIIDLTGSKSPAELLQDKTSKVILTSRDGKMGDEEERNNAGTPVTELTKQMDNVFSDAPETSFVPINVVPPLEAMTSKERQSCKRRFSDAEESLPKKQLSLENDQEVKSVSHNDSSKRDAVIDLISDSSGELDDPSYCIKEGDDISEEIEYKILVNFFRTMGYSQSIVEKVIGVLGQSVEPLTLLEEIEKENLRFQKEQEWSSKTPKTTNLRLGSNANSSHKLEDEDISCKKNPLKTTHTSNETRTERHKARDMPSTQVDAEDKMHVSVCKPVSPDKSSAICYKKTDIYCPGKNHNSTSSDAETDGFVPLSPPQAGAPKDVDFVARGSSDVRCTSAKSKTAVHQKSAGPSPVQNSHSVVEDQLGHCSSYQVRSPNQHTSQMSNFENPTQAHVLSSEIHSANPDREVSGSHRRHIDPSITGVQRFLESLKKPYRLELKNEPGKPYLKHIIIDGSNVAISHGLRKFFSCRGIAIAVDYFWKRGHRNITVFVPQWRTRRDPSITEQDFLTQLEDVGILSLTPSRMVLGARIASHDDRFLLHLADKTGGVIVTNDNFREFVTESLAWREIIQKRLLQYTFAGDIFMVPDDPLGRNGPRLDDFLQSEGCSRDFLSAQKALQSREQYSSETPLFMHVPNPASSSQQPKNRAHGDHSAAWLPLDTNMKACLSIPPQRSASETVWLREALIKIFPDYEQRQKIDKILADHPFMRDLNALSAMVLD
What is the function of this protein?
Potent suppressor of cytokine production that acts as a regulator of innate immune signaling and inflammation.  Acts as a key negative regulator of select cytokine and chemokine responses elicited by TRIF-independent Toll-like receptors (TLRs), thereby limiting inflammatory cytokine responses to minor insults (By similarity).  Has ribonuclease activity (By similarity).
What are the official names of this protein?
NEDD4-binding protein 1, N4BP1.
What is the protein family that this protein belongs to?
Belongs to the N4BP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Nucleus, nucleolus. Nucleus, PML body. Note=Primarily localizes to the nucleolus. Also localizes to the PML nuclear bodies, when desumoylated.
Protein: RL6_CAMLR
Sequence: MSRIGKQPVAIPSGVEVKLEGNLLKFKKGNLAKELDTKANVNVEIKEGQILFSPKGEDRQSRAYWGTYRALTQNIIIGLTDGFSKTLEINGVGYKAALKGKVLELALGFSHPINYAIPEGIEITVDKNNIIVKGSDKQVVGQVAAQIREFRPPEPYKGKGVKYSTERIIRKAGKTSKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: KATG_SALTI
Sequence: MSTTDDTHNTLSTGKCPFHQGGHDRSAGAGTASRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYSALKGDLKALLTDSQPWWPADWGSYVGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAAAASHVGADPEAAPIEAQGLGWASSYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPDIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKARYIGPEVPKEDLIWQDPLPQPLYQPTQEDIINLKAAIAASGLSISEMVSVAWASASTFRGGDKRGGANGARLALAPQRDWEVNAVAARVLPVLEALQKTTNKASLADIIVLAGVVGIEQAAAAAGVSISVPFAPGRVDARQDQTDIEMFSLLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTVLVGGMRVLGTNFDGSQNGVFTDRPGVLSTDFFANLLDMRYEWKPTDDANELFEGRDRLTGEVKYTATRADLVFGSNSVLRALAEVYACSDAHEKFVKDFVAAWVKVMNLDRFDLL
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PGK_MYCUA
Sequence: MTIHSLEDLPAEGVSGRGVLVRSDLNVPLDENGVITDAGRITASVPTLKALLDGGAKVVVAAHLGRPKDGPDPKLSLEPVAAALGEQLGRHVQLAGDIVGTDALARAEGLTDGDVLLLENIRFDKRETSKDDGERLAFAKQLAELVSPEGAFVSDGFGVVHRKQASVYDVATLLPHYAGRLVADEIRVLEQLTSSTERPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFLAAQGYSVGTSLLEKEMIDTCRRLLDTYHDVLRLPVDVVVTEKFAADPPPQTVAADAIPADTMGLDIGPGSVKRFAALLSNAKTIFWNGPMGVFEFPAYATGTRGIAEAIVAATGKGAFSVVGGGDSAAAVRALGISEGSFSHISTGGGASLEYLEGKTLPGIEVLGRPQPGQTEGGGPA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPUB_NEIMC
Sequence: MPIPFKPVLAVAAIAQAFPAFAADPAPQSAQTLNEITVTGTHKTQKLGEEKIRRKTLDKLLVNDEHDLVRYDPGISVVEGGRAGSNGFTIRGVDKDRVAINVDGLAQAESRSSEAFQELFGAYGNFNANRNTSEPENFSEVTITKGADSLKSGSGALGGAVNYQTKSASDYVSEDKPYHLGIKGGSVGKNSQKFSSITAAGRLFGLDALLVYTRRFGKETKNRSTEGNVEIKNDGYVYNPTDTGGPSKYLTYVATGVARSQPDPQEWVNKSTLFKLGYNFNDQNRIGWIFEDSRTDRFTNELSNLWTGTTTSAATGDYRHRQDVSYRRRSGVEYKNELEHGPWDSLKLRYDKQRIDMNTWTWDIPKNYDLRGINSEVYHSFRHIRQNTAQWTADFEKQLDFSKAVWAAQYGLGGGRGDNANSDYSYFVKLYDPKILTSNQAKITMLIENRSKYKFAYWNNVFHLGGNDRFRLNAGIRYDKNSSSAKDDPKYTTAIRGQIPHLGSERAHAGFSYGTGFDWRFTKHLHLLAKYSTGFRAPTSDETWLLFPHPDFYLKANPNLKAEKAKNWELGLAGSGKAGNFKLSGFKTKYRDFIELTYMGVSSDNPNKPTYAPLSDGTALVSSPVWQNQNRSSAWVKGLEFNGTWNLDSIGLPQGTHAGVNVSYIKGKAKQTNGQETPINALSPWSAVYNLGYDAPSKRWGINAYATRTAAKKPSDTVHSNDDLNNPWPYAKHSKAYTLFDLSAYLNIGKQVTLRAAAYNITNKQYYTWESLRSIREFGTVNRVDNKTHAGIQRFTSPGRSYNFTIEAKF
What is the function of this protein?
Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex and is required for heme uptake.
What are the official names of this protein?
Hemoglobin-haptoglobin utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: DNBI_HHV7J
Sequence: MADDNETVVSAPICTAAWLYILPKEQKLIEILTTLSLMEKRKSVVISPLLLNLTVENDFFPTVKTPIINYGGTVITKITSFMPVCFFFHGTDVFLKEAEDHGNLDKLCKQTREKFNLQEFVVNGNRKSVDIGKICESVGRNADDVLCHIVVGNGFKELLFAGLLIPCVEEQIQVQVGECLAIKIPLYSATLFESEETLCIDTCTEFIQENGFYAPQISEVLFYLIFTSWGMTLRFNNTLELIKAGLKQFIQDTEQTVKLAPNKTYHGIPGQKLSPIEKDHLMLVDAVITELTFSYTAEYLDSIYENNQIMNFSEWPIIKSAETHEEKIVELKKLRLHLSSHVAALVFAANSILYSNKLAYISNTKQAFNSAITQETLLRSIQFCNSLSSLNEDFYNDARKLIKCNSSPCKEDKFSAFHLAYACATCPQILSHIIWNLNRMSIYNTNCGNSEIYNHIVNCSSNLCEFCEGKCCHSCIGTALIRINSRLPQISKTTKKEPIVMTMFSRFYADVDVLGSFGKKGVNESKDPMKEAQTTPSLDRFKFLGMIHDYCKKNNLIDAITGEDNLNFKSQNDFVNMINDLIQCIEEAVSKCISEMRKTQTSREQIENCLQSFNIDTTPLSLAFSPFFVFTYYKVILIVLQNLALIIGTGYVVDRPCTGNLISKWLMQQYQSLYGAFYNSHFKKGFLNMKTVKIASNVDMEQYIDFNLFKSGKYAKTSIQAKLCRLSMQCLKDFRVKNRPFNKPNKNTQNNPFFKKVKQKKNPLSGCLSFLLFKYHERLFPNLKISCLEFWQRILLNNMPKTIDIGNVEDMRSFIKFTFRVTNSYDEIDLLDIQPECLLSFIEYYFHNKLLSVLGYRDYLTSLHALTSKLVPQNPMLFPVFLKEHPTFSSVQEYVMHVKKLVGNGLKEPMTASLTKEPNFGSIFTGRSIITFGLMIEKFVSVASRDYFHFGQLGWIAGSGVDRNLNPPSSGLQDFRFMRQKFVIATKLCDIIVKKVKREAIVYDVEVIRGKVLNIIESLSNSVNPELLILAEVMKDRDSKPTMDDMLFYVDGREPLAKSVMNKIQHLTDLNVHDFSLSTLLSVFEEQVEDSAAIYDFSELLVEGNEQGFGILKCEETEHENEEPSLKKARL
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework- associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Protein: MUTS_MACCJ
Sequence: MSKPTPMMTQYLQMKEQYKDCILFFRLGDFYEMFYEDAELTAKELEITLTRRDKKNNIPMCGVPHHSAKVYIERLIEKGYKVAIAEQMEDPKQVKGMVKREVVKIITPGTVMDDMISENESNYIASIHHEEGFTLAYSDVSTGELKVTQLNEDEMLNELSSVNPKEIITNIDLNEVLINKIKMITDVISRFEVNDTFKQADGVDQSLQPAVNLLLSYIQYTQMRALAHIDEAVYYEPVHYMRLDMYAKRNLELTESIRHKNKKGTLLSIFNQCKTPMGNRLVKEWIERPLLNRQEIEERHNGVELFNDNFILRHQLREALTHVYDIERLAGRVQFGNVSAKDLVQLKYSLEQLPMIQSLLKEHDEVIRTLDNIDALQPLYDMLEASLLDEAPTSIKDGGIFKDGFNNDVDELRYASKNGKQWLNELQAKERERTGVKSLKIGYNKVFGYYIEISKANLVNLDVDAFGYTRKQTLSNAERFITEELKEKESLILGAEEKLMNLEYELFIQLRDFVKTFILNLKQQAKNIAVLDCLQNFSEVATKHQYIKPIISGTKVLNIEDARHPVVETVMERDQYVANDCKLDDHTFIYLITGPNMSGKSTYMRQVALISIMAQMGAFVPASYAEVPIFDQIFTRIGAADDLVSGQSTFMVEMLEAKNALQNATDNSLIIFDEIGRGTSTYDGLSLAQSMIEYVHNKIGAKTLFSTHYHELVDLEQTLDGLNNIHVAAKEYNGELIFLHKVMPGAVEHSYGIHVAKLAQLPAEIIERSSELLDEFEHNEKVRKGDSNKIIQPSFNLFEIENENTNKYNANHEHDLIIQQIKDISIDELTPIEALLKLQEIKSRIK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: SYI_ECO5E
Sequence: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPDEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVDQDALKAKFGVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKDLVESVMQRIGVTDYTILGTVKGAELELLRFAHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAWWDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGLADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYTEPELAAKLTALGDELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKVAEHAEICGRCVSNVAGDGEKRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN2A_RANAR
Sequence: GLLDVVKGAAKNLLASALDKLKCKVTGC
What is the function of this protein?
Has antibacterial activity against the Gram positive bacterium L. lactis.
What are the official names of this protein?
Ranatuerin-2AVa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: DDX56_HUMAN
Sequence: MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFRMEEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPPALRGLVRPHKKRKKLSSSCRKAKRAKSQNPLRSFKHKGKKFRPTAKPS
What is the function of this protein?
(Microbial infection) Plays a positive role in EMCV replication by interrupting IRF3 phosphorylation and its nucleus translocation.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX56, ATP-dependent 61 kDa nucleolar RNA helicase, DEAD box protein 21, DEAD box protein 56.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: VRAA_STAAR
Sequence: MDVILEQLETHTQNKPNDIALHIDDETITYSQLNARITSAVESLQKYSLNPVVAINMKSPVQSIICYLALHRLHKVPMMMEGKWQSTIHRQLIEKYGIKDVIGDTCLMQNIDSPMFIDSTQLQHYPNLLHIGFTSGTTGLPKAYYRDEDSWLASFEVNEMLMLKNENAIAAPGPLSHSLTLYALLFALSSGRTFIGQTTFHPERLLNQCRKISSYKVAMFLVPTMIKSLLLVYNNEHTIQSFFSSGDKLYSSIFKKIKNQANDINLIEFFGTSETSFISYNLNQQAPVESVGVLFPNVELKTTNHDHNGIGTICVKSNMMFSGYVSEQCINNDEWFVTNDNGYVKEQYLYLTGRQHDMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQIGVLLYSGDVTLTHKNVKQFLNKKVKRYEIPSMIHHVEKMYYTASGKIAREKMMSMYLRGEL
What are the official names of this protein?
Putative long chain fatty acid-CoA ligase VraA, Acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL32_XYLFA
Sequence: MAVQKSRVTPSRRGQRRSHDALTAKKLSIDPTSGEVHIRHHVTADGYYRGKKVIAIKASVVEED
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: GDF8_BOSIN
Sequence: MQKLQISVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACLWRENTTSSRLEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLLELIDQFDVQRDASSDGSLEDDDYHARTETVITMPTESDLLTQVEGKPKCCFFKFSSKIQYNKLVKAQLWIYLRPVKTPATVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPEPGEDGLTPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGEGQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPA_BEUC1
Sequence: MLPAANRMRRSDEFARTFRRGTRRGTRRLVVHAATTDAGEPPRVGFVVSKAVGGAVVRNRVKRRLRAVLMHRVTDLLPGTLVVVRALPPSANATSAELERDVDGSLTSLGLRAKVVPAR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: MALF_KLEAE
Sequence: MDAVKKKHWWQSPQLTWSVIGLLCLLVGYLVVLMYAQGEYLFAIMTLILSSVGLYIFSNRKAYAWRYVYPGLAGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQQVLMDRSFQAGKAYNFSLYPAGDEWQLALTDGESGKNYLSEAFKFGGEQKLALKEADALPQGERANLRVITQNRAALNQLTAVLPDESKVIMSSLRQFSGTQPLYALANDGTLTNNQSGVKYRPNADIGFYQSINADGSWGNEKLSPGYTVTIGWDNFTRVFQDEGIQKPFFAIFVWTVVFSVLTVILTVAVGMVLACLVQWEALKGKAIYRVLLILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGIKPAWFSDPTTARTMIIIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVSYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Maltose/maltodextrin transport system permease protein MalF.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CP51_SORBI
Sequence: MDLADIPQQQRLMAGLALVVATVIFLKLLLSFRSGGGKKRLPPTIPGAPVVGGLVKFMRGPIPMIREQYAALGSVFTVPIITRRITFLIGPEVSAHFFKGNEAEMSQQEVYRFNVPTFGPGVVFDVDYSVRQEQFRFFTEALRANKLRSYVDQMVAEAEEYFSKWGESGTVDLKYELEHLIILTASRCLLGREVREKLFDDVSALFHDLDNGIQPISVLFPYLPIPAHKRRDKARARLAEIFATIIKSRKASGQSEEDMLQCFIDSKYKNGRPTTEGEVTGLLIAALFAGQHTSSITSTWTGAYMLRFKQYFAEAVEEQKDVMKRHGDKIDHDILAEMDVLYRCIKEALRLHPPLIMLLRQSHSDFTVTTKEGKEYDIPKGHIVATSPSFANRLPHIYKNPDSYDPDRFGPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWTHLLRNFEFELVSPFPENDWNAMVVGIKGEVMVNYKRRKLVVDN
What is the function of this protein?
Catalyzes the 14-alpha demethylation of obtusifoliol to 4 alpha-methyl-5 alpha-ergosta-8,14,24(28)-trien-3 beta-ol.
What are the official names of this protein?
Obtusifoliol 14-alpha demethylase, CYPLI, Cytochrome P450 51, Cytochrome P450-LIA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LCIA_LACLC
Sequence: MKKKQIEFENELRSMLATALEKDISQEERNALNIAEKALDNSEYLPKIILNLRKALTPLAINRTLNHDLSELYKFITSSKASNKNLGGGLIMSWGRLF
What is the function of this protein?
Imparts immunity to lactococcin-A to naturally sensitive host strains.
What are the official names of this protein?
Lactococcin-A immunity protein.
Protein: FMT_ANADE
Sequence: MRIAFLGTPAFAVAALDALDRAGHALVAVVAQPDRPAGRGQALREPATKAWARAHGVAVLQPEKVRDGTLAAALRALAPDALVVAAYGRILGKDLLTLAPHGAINVHGSLLPRWRGAAPIQWAVAEGERETGVTIMQMDEGLDTGDILLQRALELREDDTSETLAPRLAALGGEALAEALRLLEAGAIVPVRQDPAQATLARILEKEDGRVAWESPARRVADRLRGFTPWPGAFTTLEGRTLKVLEARPAADLAAPAGEPGEAEVVAGRGLAVACGGGTALLVTRVQLEGRPAQSALDLANGLRRKRFRLGT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.