PharMolix/UniProtQA huggingface dataset:
Protein: ATL_VIBPQ
Sequence: MDQFLVQIFAVIHQIPKGKVSTYGEIAKMAGYPGYARHVGKALGNLPEGSKLPWFRVINSQGKISLKGRDLDRQKQKLEAEGIEVSEIGKIALRKYKWQP
What is the function of this protein?
Involved in DNA damage recognition.  Binds DNA containing O(6)-methylguanine (PubMed:20212037).  Binds to the damaged base and flips the base out of the DNA duplex into an extrahelical conformation, which allows processing by repair proteins (By similarity).
What are the official names of this protein?
DNA base-flipping protein, Alkyltransferase-like protein ATL, vpAtl.
What is the protein family that this protein belongs to?
Belongs to the MGMT family. ATL subfamily.
Protein: HELB_MOUSE
Sequence: MARQDRLRELLGPLHPYKSDDEEEDCAQEEEGEQEEEFVDAEELCSGGIKAGSLPGRARVSIPDEYTKEKCTVYGRFPLKGPWWRVKVQVLKPQRSRSYQVQGFPAYFLQVDMSPPDQKQICSLFLKECNLASERIQEFLKWVEKVSSFENLHFENLWETLRLFYRETEKKDKKLSTPREQQGEEMRVEKSFAFISAMVALQFPKVMEFLPSLFPRHFKRLISSSSDWVLGCIEDVLGTQPWKLGFRRITYREMKLVRCEASWTAFSQCPSLLQLMTPLQKNALVIYSKLRQTCREDGHTYIEVKDLTSGLSEHMSFEEACQSLAFLKDIDVVIYEKDYVFLSELYEAEQDIASSICELMSRPPWHLKVDVKNVLASIRGAKPNDPGSAEAVEGSKPEEVGSEQGDSVLDAQDGDDHVRSNGEHVANAEINDVPLDQDQVVALETICANAVTVLSGKGGCGKTTIVSRLFKHMEHLEETEVQQACEDFEQDQEASEEWLDCPKQSPAGVDKAVEVLLTAPTGKAAGLLRQRTDLPAYTLCQVNYSFYMWKTKNEVDKPWKFSTVRVLVVDEGSLVSVGIFKSVLQLLCKHSKLSKLIILGDVRQLPSIEPGNMLQDVFETLKSRQCAIELKTNHRTESQLIVDNATRISRRQFPKFDAELNICGNPTLPLSIQDKTFIFVRLPEEDSRSQSSKGEHRSNLYTAVKTLLQGKDFCSFESSKTSQFIAFRRQDCDLINDCCCKHYTGHLIKDHEKKLIFAVGDKICCTRNAYLSDLLPDKDQEAEGKGYGDAPDDDAKIKQDFESSTRLCNGEIFFITRDVTDVTFKRKRLLTINNEAGLEVTVDFSKLMANCQIKHAWARTIHTFQGSEENTVVYVVGKAGRQHWQHVYTAVTRGRSRVYIIAQESELRSATRKRGFPRQTRLKHFLQKKLSGSCAPSTGFASQPSSPRVGGRPDTQPPASHLCRTPDNKATADSARGDERWLSASVNDDVDTDEESAQLRGSKRIGDGFPFDEESPSKFRMVEAPSPQVSSVFQNMRLNTLTPRQLFKPTDNQDTGTAGVADDANDPSNQEMEM
What is the function of this protein?
5'-3' DNA helicase involved in DNA damage response by acting as an inhibitor of DNA end resection (PubMed:26774285).  Recruitment to single-stranded DNA (ssDNA) following DNA damage leads to inhibit the nucleases catalyzing resection, such as EXO1, BLM and DNA2, possibly via the 5'-3' ssDNA translocase activity of HELB (PubMed:26774285).  As cells approach S phase, DNA end resection is promoted by the nuclear export of HELB following phosphorylation (PubMed:26774285).  Acts independently of TP53BP1 (PubMed:26774285).  Unwinds duplex DNA with 5'-3' polarity.  Has single-strand DNA-dependent ATPase and DNA helicase activities.  Prefers ATP and dATP as substrates.  During S phase, may facilitate cellular recovery from replication stress (PubMed:11557815, PubMed:7596831, PubMed:7794903).
What are the official names of this protein?
DNA helicase B.
What is the protein family that this protein belongs to?
Belongs to the RecD family. HELB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=Predominantly nuclear. Phosphorylation at Ser-942 by CDK2 during the G1/S transition results in its nuclear export into the cytoplasm as cells approach and progress through S phase. Following DNA damage, recruited to sites of double- strand breaks by the RPA complex.
Protein: RL30_MAGMM
Sequence: MADMIKVKLVRSFVGRPDKQRRICASLGLHKMNRVKELPDNAAIRGQINKVCHLVSVVD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: MOBA_PYRHO
Sequence: MKLIAAVLAGGKSRRFGEDKLLFEINGKPLILHTIDRLEKCNLIKRVVIVASSHNEKVMREFGYEVIVDELEIGPISGLYSALSLGEVLVVGGDMPSLIPEFIDYIIKEFNNSRKIACVPRWSNGYLEPLHAAYSREFREILGERIRKGKYKLGDAIREIPNVCYISIEKLPVEWRESFFNVNRKEDLHIIT
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHBA_STRGG
Sequence: MRDDETTVIGALVHRAVEGDAQATHDLLAHVHPLALRYCRSRLNRLPGDARHFVEDLAQEVCVAVLMALPRYKDTGRPFEAFVFAIAGHKVADLQRAAMRHPGSTAVPSDEMPERPDDSLGPEERALLSSDAAWAKKLLANLPENQRELLVLRVAVGLTAEETGQMLGMSPGAVRVAQHRALSRLRALAEQ
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released (Probable).  This alternative sigma factor governs the transcription of the principal sigma factor HrdB (SigA) throughout growth.  Acts by binding to the promoter region (PubMed:23347076).
What are the official names of this protein?
ECF RNA polymerase sigma factor ShbA, Sigma factor for hrdB.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: RSSA_LEIMA
Sequence: MSAVESGSKVLRMKESDAQKLLAMRCHIGTRNQSSAMKKYIYGRTAEGSHIIDVHMMWEKLILAARVIAAVENPKDVCVCSSRLYGTRAIYKFSQHVGTSFHGGRFIPGTFTNQIQKKFVQPRVLVVTDPRTDHQAIREASLVNIPVIALCDTDAPLEYVDIAIPCNNRGIKSIGMMYWLLAREVLRLRGTIVRSVPWEEKVDLFFYRDPNEAAEEKAAAAAAAPAAEAEEGFGWVERNDDNAWEA
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRVPA_NAJHH
Sequence: DVDFNSESTRRKNKQKEIVDLHNSLKKTV
What are the official names of this protein?
Cysteine-rich venom protein 25-A, CRVP-25h-A.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y580_STRR6
Sequence: MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIGKESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPTLHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHAHVTALTSRPKLIGGARAHYPQDAIRKF
What are the official names of this protein?
UPF0340 protein spr0580.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: PUR5_XANOM
Sequence: MTYRDAGVDIDAGNALVERIKPLVKRSFRPEVMGGLGGFGALFDLSGKYKEPVLVSGTDGVGTKLKLAQQLGRHDTIGIDLVGMCVNDVLVQGAEPLFFLDYFATGKLDVDTAAAVVGGIARGCALSGCALIGGETAEMPDMYPPGEYDLAGFTVGAVEKSQLLDGAQVRDGDVLIGIASSGPHSNGYSLIRKIYERAGAPAEHVLDDGTKLIDALMAPTALYVKPVLALLKSHGQAIHAMAHITGGGLTENIIRVIPDGLGLDIDASAWTLPPVFAWLQREGAVADAEMWRTFNCGIGFVLIAAPAEAAALEQALDAQSLAHWRIGQVVPAHGDERVRID
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TROPG_TALSN
Sequence: MVKFFQPKISPLPDGIDLKGSTAVVTGASAGMGLELTRQLLQLNISTVILAVRNVAKGENVVKQLRGDPHIRTYNGNATLKVMELDMDKYDSVQRFAKHLRDEIPIVNFLILNAGIGLLKHDRSPSGHDRTLQVNYYSNALLIAELLPYLKASAERTTIPTRITWVGSRAFETTSLQKTPLQPNERVLEHMDKKEFFAPFQRYGDSKLLCLLFMCSLARQIDPKKVIINMLCPGMVNTNMSDVLPVYLRAVINVVKAIRARPVEVGVWIILNAALVAGPDSHGKFLIDKDIASESQYISSPAGQEVQKKIWEETIEELSRLTTLPPEVN
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of the tropolone class of fungal maleic anhydrides (PubMed:22508998, PubMed:24863423).  The pathway begins with the synthesis of 3-methylorcinaldehyde by the non-reducing polyketide synthase (PKS) tropA (PubMed:22508998).  3-methylorcinaldehyde is the substrate for the FAD-dependent monooxygenase tropB to yield a dearomatized hydroxycyclohexadione (PubMed:22508998, PubMed:24863423).  The 2-oxoglutarate-dependent dioxygenase tropC then performs the oxidative ring expansion to provide the first tropolone metabolite stipitaldehyde (PubMed:22508998, PubMed:24863423).  Trop D converts stipitaldehyde into stipitacetal which is in turn converted to stipitalide by the short-chain dehydrogenase/reductase tropE (PubMed:24863423).  The next steps involve tropF, tropG, tropH, tropI and tropJ to form successive tropolone maleic anhydrides including stipitaldehydic, stipitatonic and stipitatic acids (PubMed:24863423).
What are the official names of this protein?
Short-chain dehydrogenase/reductase tropG, Tropolone synthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: YOBQ_BACSU
Sequence: MLMDSLQEIICEKRTYTRLYHSHKHAYSQFLFPLEGSIDLETEGRQVKLNPDHFLYIPPQCEHRFRSIGRNECLVLDVPLHAMKIDEYRAGSGIEAALDPFWSSIRYLLTEEAKAGTANSLHMLVQYIKEKLQSHSYASIAYIHSHLFERLTIKKLAEIEHYHPAYYSSWFKKQTGKSPQNYIADLRLEEAKRMLMERNETLTVVSEALGFQNLSSFTRWFTKSTGMPPRLYRNTLYSDKK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YobQ.
Protein: ATPF_SHEDO
Sequence: MNFNATLIGQSVAFLIFVWFCMKFVWPPLMNAIEERQKRIADGLADADRAVKDLELARSKATDQLKEAKATANEIIEQANKRKAQIVDEAKAEADAERAKIIAQGKAEIEAERNRVKEDLRKQVATLAILGAEKILERSIDPAAHSDIVNKLVAEI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SOX13_XENTR
Sequence: MDNLQGELVSFPASQQECRISAKIPVSPSEGIEGHCFKVEEDYEEPALQSGTPPFFTKQDYESPPQDTNDLCELQADSSGSGRKEENLQLSKTVRDAMPALEKLLSNDWREILLGTKESLAEKELQLLFMIHQLTRLRDQLLSAHSEHRNMAAMLFEKQQQQMELARQQQEQIVKQQQQLIQQQHKINLLQQQIQHVNMPYVMIPAFPPAQTVTADPQMSLPIQPIPCKPVEYPMSLLHNSTTRGSVSAKRQETSQPLNLTAKPTDQVPNSRSSPKYRMSPVGSQGGSSMDSASSPQKANLPLGFLGEGDAITKAIQEACQLLHGQNTSPEHHQQKYRKELLDTLPEKEVQDGASLQHTEESVLGCNMDIDGSRGSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMSNAEKQPYYEEQARLSRQHLERYPDYKYKPRPKRTCIVEGKRLRVGEYKALMKNRRQDTRQGYVITSIGALQCPPSPSGFSSQSLLDNLSQLPSSDHYNPQDCNIQVVKSHLLVSHEPHGAIPMAKDICSDSEDSGKSDGELVVITD
What is the function of this protein?
Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'.
What are the official names of this protein?
Transcription factor Sox-13.
What are the subcellular locations of this protein?
Nucleus.
Protein: METE_CAMJ8
Sequence: MKNSIISYPRIGANRELKFAIEKYFKNQSSKEELLKSAKDLRIRHWQEIQKAGIDFIPSNDFSLYDNVLDAAVLFNIVHTKYKNLNLDALDEYFAQSRGYQGENGDVTALAMKKWFNTNYHYLVPECDNADIIALTGDKIFKEYLEAKELGIESKPVLIGIFTLFKLIAFKDEKTQKLAKEKLLNAYIELFDKLNELKVTWLELDEPYLVYDLSKEDIALFEEFYQELLNHKKDLKILLQSYFGDLRDIYPKLLESKFDALGLDFIEGKQSLALIQKYGFAKDKILFAGLINGKNIYANDYAKSLKLIKELQKYTQNIVLNTSCSLLHVPYSTEFESKLDSSYLKLFAFAKEKLQELKDLKEILNSSEENPLFRANQELFKNIPERLDEKVKARLKALKKEDFTRTPSFKERALIQKEFLKLPLLPTTTIGSFPQSADVRSNRLAFKQEKISAQNYTEFNQQKIKECIQIQEEIGLDVLVHGEFERNDMVEYFGENLKGFLFTQNGWVQSYGTRCVKPPVIWGDVSRTKPITLAWSKFAQSLSQKIVKGMLTGPVTILNWSFPREDISLKESTEQIALAIRDEVLDLENAGIKIIQIDEAALREKLPLRKSDWHSEYLDWAIPAFNLVHSGVKAKTQIHTHMCYSEFSDILKEIDAMDADVISFEASRSNLSLLDTLKAIRFKTEVGPGVYDIHSPRVPSVEELSLTIEKILNKLPKEQIWINPDCGLKTRAYEEVIASLKNLVTATQKIREQL
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: CAP4_ARATH
Sequence: MGSSKFKRAIGAVKDQTSVGLAKVNGRSASLSELDVAIVKATRHEEFPAEEKYIREILSLTSYSRSYINACVSTLSRRLNKTKCWTVALKTLILIQRLLGEGDQAYEQEIFFATRRGTRLLNMSDFRDVSRSNSWDYSAFVRTYALYLDERLDFRMQARHGKRGVYCVGGEADEEEQDQAAADLSTAIVVRSQPIAEMKTEQIFIRIQHLQQLLDRFLACRPTGNARNNRVVIVALYPIVKESFQIYYDVTEIMGILIERFMELDIPDSIKVYDIFCRVSKQFEELDQFYSWCKNMGIARSSEYPEIEKITQKKLDLMDEFIRDKSALEHTKQSKSVKSEADEDDDEARTEEVNEEQEDMNAIKALPEPPPKEEDDVKPEEEAKEEVIIEKKQEEMGDLLDLGNTNGGEAGQAGDSLALALFDGPYASGSGSESGPGWEAFKDDSADWETALVQTATNLSGQKSELGGGFDMLLLNGMYQHGAVNAAVKTSTAYGASGSASSMAFGSAGRPAATMLALPAPSTANGNAGNINSPVPMDPFAASLEVAPPAYVQMNDMEKKQRMLMEEQMMWDQYSRDGRQGHMNLRQNQNQPYSYTPQY
What are the official names of this protein?
Putative clathrin assembly protein At1g03050.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin in the Golgi area.
Protein: RS9B_YEAST
Sequence: MPRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKREIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAAEEAEDEE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  uS4 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (PubMed:15590835).
What are the official names of this protein?
40S ribosomal protein S9-B, RP21, S13, Small ribosomal subunit protein uS4-B, YP28, YS11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: PUR9_PROM4
Sequence: MARIALISVSNKDGLIPFAKTLTTLHGFEIISSGGTARALKEANIPVKTVSDYTGAPEILGGRVKTLHPRIHGGILAKQGNSSHQFDLEKENIKNIDLVVVNLYPFQETISDPDVTWDNAIENIDIGGPAMIRAAAKNHESVSILTNPNQYDAFLEKLEAGEISTTIKAKLALEAFEHTASYDIAISQWLSKQIESKYSPYLTSQPIKQTLRYGENPHQNANWYSAVNQGWGQAEQLQGKELSTNNLLDLEAAVATIREFGYDLGNKGNSCEKAAVIIKHTNPCGVAVSNNLSNAFNLALECDSISAFGGIVALNCNLDAATAKELSSLFLECVVAPDYDANALEILSTKKNLRIIKLSHSSIKSSERKYIRSILGGILVQEVDDKLIEPNEWKVPTKLQMSIEDKADLAFAWRVVRHVRSNAIVVASAGQTLGIGAGQMNRIGAAKIALEAAGEKAQGAVLASDGFFPFDDTVHLASRYGIKSIIQPGGSIRDQSSIDACNQLGLSMIFTGKRHFLH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PTGCB_SALTY
Sequence: MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVVSHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLHLPAEEIAAKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLAAIFTGVVLSFVWPPIGTAIQAFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPFQMQIGEYTNAAGQVFHGDIPRYMAGDPTAGMLSGGFLFKMYGLPAAAIAIWHSAKPENRAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDGTSFSHGLIDFIVLSGNSSKLWLFPIVGAGYAIVYYTVFRVLIKALDLKTPGREDTTDDAKAGATSEMAPALVAAFGGKENITNLDACITRLRVSVADVAKVDQAGLKKLGAAGVVVAGSGVQAIFGTKSDNLKTEMDEYIRNS
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of PtsG and Crr is involved in glucose transport.  Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration.  It can also phosphorylate mannose, methyl alpha-glucoside and 2-deoxy-glucose.
What are the official names of this protein?
PTS system glucose-specific EIICB component, EIICB-Glc, EII-Glc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LFTR_KLEP7
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPEQFHLSRSMKRFHQRSPYRVTLNHAFGEVIEGCASDRDEGTWITSSIVRAYHQLHELGHAHSIEVWQENTLVGGMYGVAQGALFCGESMFSRAENASKTALLVFCQDFAHSGGKLIDCQVLNNHTASLGAVDIPRRDYLDYLSVLRGYRLPERFWVPRVLFPGG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG9_DICDI
Sequence: MSHEDRGGDYYPMMDDPEDRNFIQAKYPNSTGHMSSGGGSNHMSFDDNHGIEMLRDDEHSLLHESPVSIPAIHNLDSFLTDVYNYFRGKGFMCIFFNDLFELVSSLFVVLFFTFLVCFVDYSKLFSEQMPPPALRESVNFSAPIPIWLMVFLVIFSLYWLSKLFSFFSSIKTNWEISSFYKNTLKINEDDIQTIEWREVVSKIVLVPRLCIVKENMNALDIANRIMRKENYIIGLINQRILNLSIPFPFLRNLTFITKTLEWSLMYSLFNYIFDENGIIKSEFQDPTQRKRLSRGLSRRFMTIGILGLFTTPFIFFFLLINFFFEYAEELKNRPGSLFSREWSPLARWEFRELNELPHYFQNRLNLSYSHANQYVESFPSQMLSTIAKFISFLFGSVLAVFIVLGIVSDHFIMNYQIFDRTPIWYIGILGTIVAITRSLIVDENQVFQPAKHMARTVQNTHYLPMSWVGKTHTHKVRDEFLVLFEYRIVDFVRDIFSVLFTPFILIFSLPKSSQAIIDFFGNNTVVLEGVGPICQLGDFSNIRKLGDNSFGSLNHSQNKISLTNNAKLEKSIINFKCLNPEWNTDNNELLQNLNEFSKIKNNNNNNNNNGSNNHIGNHSQLPTTSVDDFQFIHDSHYIPHEIIDAVLGTHHHSQQSNNNAPRFKTGRVDQNILNAVNDLHQSFYESQYKHKNDNFVNSI
What is the function of this protein?
Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion (By similarity).  Required for lipopolysaccharide (LPS)-enhanced bacterial clearance through the autophagic pathway (PubMed:12626495, PubMed:22575510).
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: ENO_THET2
Sequence: MTTIVGVRAREVLDSRGFPTVEAEVELEGGARGRAMVPSGASTGTHEALELRDGGKRYLGKGVRRAVENVNERIAPELVGMDALDQEGVDRAMLELDGTPNKANLGANAVLAVSLAVARAAAEALGLPLYRYLGGVQGVTLPVPLMNVINGGKHADNRVDFQEFMLVPAGAGSFAEALRIGAEVFHTLKAVLKEKGYSTNVGDEGGFAPDLRSNEEAVELLLLAIERAGYTPGQEVSLALDPATSELYRDGKYHLEGEGKVLSSEEMVAFWEAWVEKYPIRSIEDGLAEDDWEGWRLLTERLGGKVQLVGDDLFVTNPERLRAGIERGVANAILVKVNQIGTLSETLEAIRLAQRSGYRAVISHRSGETEDSFIADLAVAVNAGQIKTGSLSRSDRLAKYNQLLRIEEELGRAARFLGYAAF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CAPP_CHRVO
Sequence: MSEHDKDLPLRADLACLDRLLSEVVGEQEGAVVSGAVQAIALRRGDERSHPLPQLAPEAAASLLRACGLYAQLFNIAEDLHHNRRRRAHQLAGSAPQQGSLPRALQRLRQDGVSFHALHQLLSHAKVGAILTAHPTEVQRQSVLDGHRAVRRFLSQLNAADLTPEEREALEAKLKRAILALWQTSEIRHFKMTVRDEITNGVAYHPLAFFEALPALYRRLEREIGQLWGEEARLPSFIRVGSWIGGDRDGNPNVDAGLLRHAVTRQSQQAFEYYLQELKSLYRELSLSSRLVEAGAEVLALAEQSPDQAVSRGEEPYRRALATMQGKLRATARLRGVELACRWDERAPYRDHRELIQDLASLSASLRAHGSALLADGRLSRLIRSVDVFGFFLMPLDLRQHAAVHEGVVAELFSAAGLEEYRALDEAARVRVLIRELATPRLLFSPYLRYGEQAEKELAIFREAAAIQRDFGVEAIGQCIISNCASVSDILALALLCKEAGLIRLEDGQPRASVNLVPLFETIADLENSEAVMRALFALPWYKQLLDSRERVQEVMLGYSDSNKDGGYLTSQWQLWQAETRLVKVFADAGARLQLFHGRGGSVGRGGGPSYEAIVAQPAGSVAGRIRITEQGEVITAKYSDPAIAGRNLEALVAATLEASLGNIPGGEVDTALFDELSASAFAAYRALVETPGFMQYFLEATPVTAIARLNIGSRPASRKSLSSIGDLRAIPWVFSWSQSRLMLPGWFGVGSAVAAYVQKHGDAGLAKLQHLYRHSPFFQVMLSNMEQVLAKADLGIARRFSELVADRELAARLFGAIEAEWRKTHDAFFAITGQAELLEGNPTLRRSLETRLPFLDALGLLQADLLARLRAEPDDEDTLYAIHLTINGTSAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: CLC1_ARATH
Sequence: MATFDDGDFPAQTHSPSEHEDFGGYDNFSEAQQPPTQHQSGGFSSFNGDPASPNGYGFGASSPNHDFSSPFESSVNDANGNGGGSGGDAIFASDGPILPDPNEMREEGFQRREWRRLNTIHLEEKEKKEKEMRNQIITEAEDFKKAFYEKRDKTIETNKTDNREKEKLYWANQEKFHKEVDKHYWKAIAELIPREVPNIEKKRGKKDPDKKPSVNVIQGPKPGKPTDLGRMRQIFLKLKTNPPPHMMPPPPPAKDAKDGKDAKDGKDAKTGKDGKDAKGGKDAKDLKDGKPADPKVTEEKRPSPAKDASVETAKPDAAASGEGEKPVAVTEAEGTKAE
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
What are the official names of this protein?
Clathrin light chain 1.
What is the protein family that this protein belongs to?
Belongs to the clathrin light chain family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Protein: GCST_SHESH
Sequence: MANKTVLFNKHLESDAKMVDFHGWDMPLNYGSQIEEHNAVRQDAGMFDVSHMTVVDVTGTDACAFLRKLLANDVAKLKVPGKALYGGMLDHNAGVIDDLITYYLTDTHYRVVVNSATREKDLAWIAEQVKGFDVEIVERPELAMIAVQGPNAKAKAATVFNDAQNAAVEGMKPFFGVQADSLFIATTGYTGETGYEIIVPEDEAQALWQGLLEAGVKPCGLGARDTLRLEAGMNLYGLDMDETVNPLAANMGWTIAWEPQDRDFNGREALAAIKAAGTEKLVGLIMEAKGVIRPGMSVFFTDGEGVEQQGTITSGTFSPTLGYSIAMARVPRSIGDTAEVEMRKKRVSVKVVAPSFVRNGKQAF
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RL10_LEPBL
Sequence: MANQEKVEAVALLKGKLEEKNNFILACYSGLTVEEITGLRAQLRKEGSEMKVLKNNLFLRALKESGAHKDKNISFGPEYQGPLAAIFAKDNLPTVAKVCKDFAKVNKNLIVRAGYMDGSVLDANGVEAIAGLPSREQLLAMIAGGINAPARTIASGINQIVASLARAIQATAEKNNA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GMHA_PSEPW
Sequence: MDMQSRIRRLFQASIDTKQQAMDILAPHIEQASLVMVNALLNEGKMLACGNGGSAGDAQHFSSELLNRFERERPSLPAIALTTDSSTLTSIANDYSYNEIFSKQIRALGQPGDVLLAISTSGNSANVIQAIQAAHDREMIVVALTGRDGGGMASLLLPEDVEIRVPSTVTARIQEVHLLAIHCLCDLIDSQLFGSEE
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.