PharMolix/UniProtQA huggingface dataset:
Protein: MURD_STAEQ
Sequence: MLNYTELENKNVLVVGLAKSGYEAAKLLLKLGANVKVNDGKDLSQDAHAKDLESMGIEVISGSHPFSLLDDNPIIVKNPGIPYTVSIIEEAAKRGLKILTEVELSYLISEAPIIAVTGTNGKTTVTSLIGDMFQKSVLTGRLSGNIGYVASNVAQEVKSDEYLITELSSFQLLGIEKYKPHIAIITNIYSAHLDYHETLENYQNAKKQIYKNQTKDDYLICNYHQRHLIESENLEAKTFYFSTQQEVDGIYIKDGFIVFNGIRIINTKDLVLPGEHNLENILAAVLASIIAGVPVKAIVDSLVTFSGIDHRLQYIGTNRTNKYYNDSKATNTLATQFALNSFDQPIIWLCGGLDRGNEFDELIPYMENVRVMVVFGETQDKFAKLGNSQGKYVIKATDVEDAVDKIQDIVEPNDVVLLSPACASWDQYHTFEERGEKFIDRFRAHLPSY
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPC_METEP
Sequence: MLNQLRPALVLLVALTAVTGLAYPLAVTGIAGALFPAKAAGSLIERDGRIIGSSLIGQSFTGEGYFHGRPSATNAADPADASKTVPAPYNAASSAGSNLGPTSAALAERVKGDLAALKAENPGRPVPVDLVTTSGSGLDPDISPEAALFQVPRIARARNLPEARLRDLVAGQVQGRTLGLLGEPRVNVLALNLVLDDLAKR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRPA_CHLSY
Sequence: MSRIAETFARLRAAGRIALMPYLTVGFPERTSTLELVPALEAAGASLFELGIPFSDPLADGTTIQRATQRALENGITIADCIATVAELRARRVAAPLLLMGYYNPLLRYGLERACAALAAAGGDGWIIPDLPLEEADDLRQLAAAHQLDLIMFIAPTTPPARISQITAQASGFLYIVSLTGVTGARQTLAGNLTDLIANVRQQTNLPLVVGFGISQPAHIAEVARIADGAIVGSALIDRLERLPPEDRVSGAAAYIRELLSAVARP
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: YMR1_SCHPO
Sequence: MENIKVAKVGNVKFVNKGNELNGTLHLTAYHSIFSISENGKEIWTAYSMINNVKLCSNEKSFCIRIQCRDFMFFCWRFQSTEDAMDVYDTLQELMSINSINMLYAFYYMPSGDEEKLPSSWKSFLLENEYRRMGVGDSTQADGAGGNWRITKINENYSECHSYPQALAVPASISDSVIYYGCKYRSKNRFPTLTYLHKNSFSITRASQPLVGIRQNRSAQDEKLVEAIFATSIIPGKENLIVDARPSTNAMANIAVGAGSENMDHYRFAKKIYLGIDNIHVMRDSLNKIVNALKNTDISAAPPLIELLNRSSWLKHLANILQGAVLIVKTVHFRHAHVLVHCSDGWDRTSQLCALPQLCLDPYYRTIEGFFALVEKDWLSFGHRFAERCCHLPGKRIFTIDSSYSEEPPQSSPSSTLQYTFSTVRSALSGFSIDHSEKMMSPVFHQFLDCVWQIMDQFPNCFEFNERFLRRLLYHLYSCQYGSFLYNSERERAQASVSTHTRCIWDYFLSRKDEFKNPNYVPYDDVIMPDPSSLRWWSASFAQPDENMNIPSPSESPSL
What is the function of this protein?
Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P).  Involved in the control of PI3P-dependent signaling and in the maintenance of endosomal system integrity (By similarity).
What are the official names of this protein?
Phosphoinositide 3-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_STAA3
Sequence: MMENSTTEARNEATMHLDEMTVEEALITMNKEDQQVPLAVRKAIPQLTKVIKKTIAQYKKGGRLIYIGAGTSGRLGVLDAAECVPTFNTDPHEIIGIIAGGQHAMTMAVEGAEDHKKLAEEDLKNIDLTSKDVVIGIAASGKTPYVIGGLTFANTIGATTVSISCNEHAVISEIAQYPVEVKVGPEVLTGSTRLKSGTAQKLILNMISTITMVGVGKVYDNLMIDVKATNQKLIDRSVRIIQEICAITYDEAMALYQVSEHDVKVATVMGMCGISKEEATRRLLNNGDIVKRAIRDRQP
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: VP37B_HUMAN
Sequence: MAGAGSEARFAGLSLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNLLYQPQLDTLKARLTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEEDTENMAEKFLDGELPLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRLPELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQCPPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPGFILQ
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.  Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.  May be involved in cell growth and differentiation.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 37B, hVps37B, ESCRT-I complex subunit VPS37B.
What is the protein family that this protein belongs to?
Belongs to the VPS37 family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein. Note=Recruited to the endosomal membrane in a VPS4A-dependent fashion.
Protein: NG06_SCHPO
Sequence: MDINDPSFSSTENGIYELLSRGYAAIEAATERDLKLPELGDIIGQVHAPEYISQVLSGWKPFYLRSVVNIPDRIFEQYNRTECFTQMGLFAEIQRAWITVDNRLFLWDYLSGQNFQAYEDLSHTIVNVKLVRPKANVFVSEIQHLLVIATSQEMLLLGVTIDEKTGELSFFSTGIQISVQGINVNCIVSSEDGRIFFSGNKDPNLYEFSYQLEEGWFSRRCSKINITGSVFDNFIPSFFSFGTHGDGIKQIAVDDSRSLLYVLRETSSVSCYELTKNGVNRCVFYSFSSMISQAQMLNATSPLLDPRTTQIVSIVPIPAYESQQIYCVAITSTGCRFYMRGGRGPISHYAPSNSTLSSTPPSTLQLTFVRFPPPMQVENYASSRNYPANPFFLQNQSTSQQQPERSSAVKTTPMKCSSLSNIYTSDLFFAISSSNTNEGDVVCCTAPEVGRIANAWQSGTQPSLIESSMYVPIKGFVQDIKCIQNSRERNELVSQFNTPPPTFAILTNTGVYVVVHRRPIDVLASAIRMGPSLSSGIDGQVQLFFESVGRAEGCATCLGIVSGCLDQGDFSHAAANFSGSTTKLAQADLLDIVKKYYIEFGGKAFIDQSRYNNQYDSSSLEFVRLSGCHDGLASSISRIIRNVWKNHVIIAKKMQNKRIHYAPAFNATEILKIQSGLLYLSTFLENNKSFIEGLNSPNTLIGSSNVADEIAVQAEHRALSALLLVLQQIVEGISFLLFLNDTGVSDFHEIVSSTSIDIQKSCSNMTFGEFFTSKRGREVTKELVNSLVNRHLQSGGNIDMVSQLLRKKCGSFCSADDVLIFKAVESLKKAKDTVDIEERQSLIELSYTLFKKAAHVFTPEDLRLAVEEYKSLNAYTTAVNLALHVASARDDRNQALSYLVDGMPENDPRREPFESRTKCYSYIFEILDSLESQMSNDSSAIKVDVYDTIQRSKDELFHYCFYDWYSFKGLTDRLIEIDSPYIQSYLERNSTKDMKIADLLWQYYAKREQYYQASIVLYDLATTHLAFSLEQRIEYLTRAKGFGSCHVPNSLRHKMNKVMLSVLEQLDVASIQDDVLIAIRGDMRIPTSKREELSKQLDGEIIPLSDLFNNYADPLGYGEICLSIFQCADYRGINEILNCWESIIKTTHENAIISPVGSSPVEAVSSTLKNLTLRFSQSENVFPIEQIIDITERYAFDQQGEAVATGWVIDTFLGAGVSHELIFIVLNQLYDRREKPWQGKDRLFFLIKEVTHLLKLWHEVSVRAGVAQTSKPSFDAPLVLEAIEKYKNALGAPDTATKSCKENLISLDSEIRQTY
What are the official names of this protein?
Probable nucleoporin C890.06.
What is the protein family that this protein belongs to?
Belongs to the non-repetitive/WGA-negative nucleoporin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Nuclear rim.
Protein: GCY8E_DROME
Sequence: MYGLLLENLSEYIKSVYGEEKWEDIRRQAGIDSPSFSVHQVYPENLLQKLAKKAQQVLGVSERDFMDQMGVYFVGFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYLKFSYPRMRAPSFICENETKQGLTLHYRSKRRGFVYYTMGQIREVARYFYHKEMHIELVREEILFDTVHVTFQLTFDNRAFTLASLAMTREEKHLPISAHVLFEIFPFCMVFGADMVVRSIGNSLMVILPELLGKKITAWFDLVRPLIAFKFQTILNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGSEPEKSLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDLKDPSTGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIGPNYKIIERGEIDVKGKGTMGTYWLEERENRLPLQLTAALQVHPLSPVPPTPTPKTKAIMPPVSKPLTPMMPVSVSLAASMPTSNVPAVDVMASSSSISGLALTAAAAAHMSLHHQAVVAEALTGASVEVALPSVASGATGAAAGGGAPSDDRNSRIYSPVTFKDVARRSVANSPVRSCAQPDQERRRESRSNSTGHVFMRTPSEIFGSLILDTEEFLEDLQISRSSLANNNNNQSPCGFSPTPPFRIGSAPPKPRPSNPDKFTPEELAAMDQLTPPSTAPARETASCSSASLDRDKATKLKKITFSNSSSLDATTPTALAAVVCPMRTKSPPMAVAPVMHMVQASTSKGDGQRPGSKDSVSSISLHSPPPHRSNSAPARPHSMSKAARKAFLAAKQTKAMEKLDKMIEEVQEVESQSVAKAANMRLALYGHDGGGDLAAGGCPLFLPPPPQQQQQQQQSLMPSSISDSGLCSHGHSHAPSCHHMDPKMTNSQSFQHSPRGGITHQCCSGFGHGNGRHSHRMHSNACRIL
What is the function of this protein?
Heterodimers with Gyc-89Da and Gyc-89Db are activated in response to changing oxygen concentrations, alerting flies to hypoxic environments.  Under normal oxygen concentrations, oxygen binds to the heme group and results in low levels of guanylyl cyclase activity.  When exposed to reduced oxygen concentrations, the oxygen dissociates from the heme group resulting in activation of the enzyme.
What are the official names of this protein?
Soluble guanylate cyclase 88E.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PALC_NEUCR
Sequence: MPYPFVLPTTSSFSFTSCFSCESHPSLPLNASTRRGVVREDLKAFKRTPREHQVAKLPTVVSSLIAYLPYLFAVDAGLSQQAINGEEIAVILKTAPIIEWRPTLSDNAAVAVPGKDPARVKVHSLEYEVFFVLSCLANAHTLQARTALHPLYVLSTAPVGTQQRQVAVSAATKNLLDAASIYDYLALRAEGLSSGYGMAPPCADISPAALRAQCSLAMAEATLLAVLKDDPYPAVVAQDRNKNDTEWMYKAPDIPKVRAHLFARLCLAASEHAAQAYSLCAGLARAEGGAKVTESFLKYLDNLRRTSRAKACRFFGIDSELGGQTGTAIAWLNAGLQELGVERNPSEGGSKRSGGLGRLKEKWTEKREDKKVERGLDWGADAGRLEESRVYEMLWEKWSKQNDTIMTQVVPPSGPLLQQMPMGREIHTLKPFQPPQLDPPTLEAMRAPPERSDDAALYPSSDEDDTMIGATIGAFPGTQGHFRTGTPNYF
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor pacc-1 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palC.
What is the protein family that this protein belongs to?
Belongs to the palC family.
Protein: Y1558_DICDI
Sequence: MVFSLKESSDSISKPSSLKNSTIIENPEILNNNNNNNNSNNIIKSPNFLLSQKQRSINISNEQTQRELNNNGGNLDHRDPNSPKYLTSSHSSVVIPQDNSNNNNNNNIRISTSPILTEISENGLLESPTSPIRTSSTPTTPTSPPFITSPPFITSPKGLNSPRRLVGFFSKSTSYQSLLANNNNNNNNSNNSNNNSNSSNSNISCSNNSNKISRLINNSNTTDSNASIRSSNNNNDDFDNNDDEDLNSINNSSGIGIGVSSDYSLMGSSSSINGNTTTTTTNTYSYNDNDNVNEYSPKGKRLIRHEKSKSSPPLSPITPYYENLVIKGNYTNSNNYNNYNNYYYNNNSSGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNISGNSGYNNSRDDLFKRPFEMNKESSPTNSLIPNVSALKLNRVIKSSNGSTIFTSTSSDIASENDNNKNNENENENENENENENENENDNDSDSENENENDNSIGNKSNKSNSELSIEEQEKKKEKDLENYINMINNSGFITNDSNNNNNNNNSGNNNSFISNGSPFSPIKEESPQPSPTFSPKPTLQRQRSNSKNVLYSPNASPSNSCKIPTPPLLHNISIIDTSNNNNNNSNNIENQNNNNNNIDNNIDNNIDSIDKKLKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNDDDDDDNNIKKTPNNKINTNENPMIITNSVLKRSGNIDYLQINNNYVIPSPSPGTQLSECTNQQMKYNPPVSIVDFTLIEKIGEGGFGQVFLAKKKDTGEIVAIKRMSKELIWSKNKVSHIKNERDILAQGKNHRWIVSLVYSFQDDQYLYLAMEYVPGGDLRSLLSALNSLDEDSARFYMAEMVEAVDSCHRLGYCHRDLKPENFLISRDGHVKLADFGLSKNVVTRYHLRSASADNTINTTTSTPTTSSNINQLSSSMIEHTPMKFGAAANGNGPLNSSVTDFGSFKDLSVAARLAYSVVGSPFYMAPEVLQATRGYGDEVDWWSLGCMFYEFIFGVPPFDGDSPEEVMETVLKWKTMLQRPDGVSDELWDLISGLINDGSTRLGSGEKGVENIKNHIFFNGVPWGKLHDLDPPFVPLLQGDYDTTYFENTEKLDNNFLLQQTQQLSLLPPPLPPPPQTPTQPQQPSLPPQTPNDKMIFDKIRSPVVYTNTHSGNIITSRSRPRNILGFTYPRADDQPLLWNNNNNNNNNNNNNNNNLLKNFEELTILNNNNNKNKNKGNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNKNNSNNKTVTIPISTGRLLNEIDNCNNNNNNDENNINTGNLTPPNSSPFNSGENLNFEKQEPTSPYGSYSKQQQ
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0278845.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Protein: RGA8_SCHPO
Sequence: MISSFSNGFWSKDYATGVKKLFDCLDNGVEENEQVKNLLKLYKEANEEFGEKLQEITKECLKGKKPENTEDGATSNKAFEGLRSEIANQGKQHIRIAKDLETLIIAPFSKMSIDHSQKLQTSQQVLTNQIKSYEKKYYTLKKTKSAYYNKCRNLEDYEEESKESNETTSEAITDLTTVSSPQQQSLLENDDDLIQLGFMEFRPEELKEVLAQVLQEIPLQDYRVPILGTYPNTCSGNIIVSWLQENLPVPTLVAAEAFGQDLIAQGFLRHMGVGGSFVNSTNFHYQWKDKAFQFAGLNSVDSLVENAKALPLVGEYLSDYISHRKLYSSETQSQRLKREVLDANKIYSESVVDLDKCRTLVEETIADHLQFLQKCETDRVLYYKDFFMDLSTIISNFLPSMKLLADQIVVYQEIIQPESDIRYILESAATGPFLPRVEIYEDYYNDIKDQIFGVDVEFLSHRDKKRVPIIVSTILSYLDLLYPTLASDEVRQNIWLVNSPLSSVHQLREALNHSSSVTKEVLSQYTPSVVIGVLKLYFLELPDSIVPSSAFELIRSIYMNHSNDTPYRLRLLQNLLSQLRRVNLATLSAIITHLNRLITLTPNKETFTINLANSLSLCISRPATWNLGIQHDKHPTKFMEDLLTYGPSIFEELRKLNSSKRVSDRVLYQSSATPRSTDVSPTRPDSISSVRSHTAVESPRSSFEELQPSEIPAESEFTLENVPTSLIRSSYALNTRKTRRNFSHSSASNESAAIFIDQDAKIVNEAVASRDSSLSGS
What is the function of this protein?
Acts in signal transduction.  Negatively regulates the pak1/shk1 control pathway.
What are the official names of this protein?
Rho-GTPase-activating protein 8.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the cell ends during interphase and to the septum- forming region during cytokinesis.
Protein: GEX2_ARATH
Sequence: MVGIFNIVIDEENFKVLDSSLHFEVEAGLMYPSVSVVSWMGLANVFEAGMNASILILPKDAFGNNISFSGKKMEFQEFSLSLISENGSFAGVLNSTHIRWIVSGYISIDFVLVTSGKFLLLVEKESQTLNGGPLPLEVNSGPLDVSNCVSIWKSELSTWQIFSKMEILLHQKDRFGNIVSGFYEFDADVVEVETGLSIPVADFQFEYVEPGIQLMSFTLSEPGNFLLTLSDMKHNKSISSMPYVYTVYIGYCDGSRSIVNGSGINASIAGESLGFSVYLKDAYGYPSPVQVDRLQVRIVLEIDSSIILPTIQPREALNGTGSSHQAATPLYEKHGGRASGNLVTQASIFDVTYTPKRTGIYRIFISSGNIVLNGGQPFIKEVYAGEVNVAACSVTQFNGKVPKEIKNEIVVLLLDGFYNPVPSQPSRLKFEITSANTSSFTTWEFVDNNDGTYTGSYLAMEVGTYRMCISFDNKHIQPCPFDVNVYSNGYFPRAYDDPVNVWEDESISFNPLENDYFAGDNASMLGFSQPGHGSLLRDGNLLRYTPMKNFSGNDSFLYTIADINGNLAAATVYIFVLTAPPQFVSFSGGLQATEDLISPRYGGFSGLEISYSDLLENISVMVQALSGSVILSPMLMQFRPPGSGKLSVSNGGEDRRVLILEGQVGVINPALQSIQYLGNENFAGVDSLRLSTKNKNGINHLDVPVFVEPVNDPPFINVPQYIMLESNGSESLIFHPERDKFNFSVGDPDLVNFPGGESHFLVTFSLEVTDGFLLTNLPSELINSTELKFKNLFQWQPIQTYAAISKHVNVKASGIRFRGTIRQCNDLMQQLLHRGGENGAVLTLKLSDMGNYGCFLDCTERISLPLHAEARVNLIRKRPLSSLGAHGTFMKYLVVVPFSFFSIKLFSLLMVLIG
What are the official names of this protein?
Protein GAMETE EXPRESSED 2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ILVC_YERPB
Sequence: MANYFNTLNLRQQLAQLGKCRFMARDEFADEAGYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVAYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSAVVKAVQPLMKEGAALGYSHGFNIVEVGEQVRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVSEGTDAAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGAFSSGMMADWANDDVKLLNWREETGRTAFENAPQFEGKISEQEYFDHGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANAAVPLLKEKFMDSLQAGDLGKSIPGSAVDNAQLRDVNEAIRNHPIEAVGHKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RUVA_PROMA
Sequence: MISWLNGLKIEIWENGTRKGVLISCSGVGYEVQLLSRSLQLLNTSKELILWVHEVHREDGSQLIGFLNKLERDLFRKLISVSGVGPQLAISLLEKNPAEQLISAITKKKIAQLTSCPGVGKKTAERLVIELQNKLSDLIGSSLKKTNNHLELEYETNVADEVRSTLLNLDYKNSEIEKAFLEFETSSKSIRSKAQESFEVSKGLDFETLLKETLIRINTESG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: GUAAB_NATPD
Sequence: MVEPTAFIDEKIAEIADDVGDANAVIALSGGVDSSTAAALAYEAIGDQLTPVYVDTGLMRKGETDQIRDTFDYMDSLRIIDARDRFLDALSGITDPEEKRHAIGEQFIREFETVARDVDADYLVQGTIYPDRIESEGTIKSHHNVGGLPEVVDFEGIVEPMRDLYKDEVREVARELDLESIIAERMPFPGPGLAIRVLGEVTDEKLAVAREANHVVEEELEEYEPWQALAAVLGKATGVKGDNRVHGWVVSVRSVESRDGMTARAQELDWETLQRIQSRITGENENVARVVYDVTHKPPATIEYE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: CA112_CONBU
Sequence: MFTVFLLVVLATTVVSFSTDDESDGSNEEPSADQAARSAMNRPPGCCNNPACVKHRCGG
What are the official names of this protein?
Conotoxin Bu1.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SULA_YERPN
Sequence: MRTQSLKPYHANYHSLTTNDSPTRVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: F117B_MOUSE
Sequence: MSQRVRRNGSPTPAGALAGGAVGPPGGPGSRLQPMRATVPFQLKQQQQHGSPTRGGGGGGNNGGNGGASGPSGGGGSGGPRTASRSTSPTRGGGGSAAARTSPTVATQTGASVTSTRGTSPTRGTAPGARSSPPRPQPPPPLLGTVSSPSSSPTHLWPSEVIAAPPSARVRHRRRSPEQGRPSAEKRSPSAPVCKAGDKTHPPSSSSSSIIRRTSSLDTLAAPYLAGHWPRDIRGQAAPCMRDKATQTESAWAEEYEKKKGSHKRSSSWGSTEQLKEIAKLRQQLQRSKHSSRHHRDKERQSPFHGNHAAINQSQAPAPKSTLVPAGPITKSSGSRFRNSVEGLNQEIEIIIKETGEKEEQLIPQDIPDGHRAPPPLAQRSSSTRSIDTQTPGGADKGSNNSSRSQSVSPTSFLTISNEGSEESPCSADDLLADPRDKENGNNSPLPKYATSPKPNNSYMFKREPPEGCERVKVFEECSPKQLHEIPAFYCPDKNKVNFIPKSGSAFCLVSILKPLLPTPDLTLKGSGHSLTVTTGMTTTLLQPISMASLSTNTEQERVSRGTSTVLPSASLHAPPEPIEEAEG
What are the official names of this protein?
Protein FAM117B, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein homolog.
Protein: BCHN_RHOPS
Sequence: MTVHVSNCAATAEDPVSREIRTESGQREVFCGLTGIVWLHRKIQDAFFLVVGSRTCAHLIQSAAGVMIFAEPRFGTAIMEEKDLAGLTDANIELDRIVTQLLTRRPDIKLLFLVGSCPSEVIKLDLSRAALRLSQRFSPGVRILNYSGSGIETTFTQGEDACLASLVPELPAAQDEKSSLLVVGSLADVVEDQFMRMFDALGIGPVQFFPPRKSTALPSVGPNTKILMAQPFLPDTVRALQERGAKRLAAPFPLGVEGTTGWLRAAADAFGVDPAHFDKVTGPNRARAERALAAYRTELADRRIFFFPDSQLEIPLARFLSRELSMKLVEVGTPYLHREHLAEELKLLPAGVAITEGQDVDLQLDRCRLARPDIVVCGLGLANPLEAEGITTKWSIELVFTPIQGYEQAADLAELFARPLVRRAKLVA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: QUEF_BRUA1
Sequence: MSENTIYSGLKQLGSHTDIPLTPEEAVLERVANPQEGTPYCVRFTAPEFSSLCPMTGQPDFAHLVIDYVPGKWLVESKSLKLFLFSFRNHGAFHEDCTVTIGKRLVDLLEPEWLRIGGYWYPRGGIPIDVFYQTGAAPLNVWIPEQGVANYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_MYCBO
Sequence: MSKSSRGGRQIVASNRKARHNYSIIEVFEAGVALQGTEVKSLREGQASLADSFATIDDGEVWLRNAHIPEYRHGSWTNHEPRRNRKLLLHRRQIDTLVGKIREGNFALVPLSLYFAEGKVKVELALARGKQARDKRQDMARRDAQREVLRELGRRAKGMT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL18_YERPP
Sequence: MDKKAARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEILVAASTVEKAINEQLKYAGNKDAAAAVGKTIAERALEKGITKVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: FPG_PROM9
Sequence: MPELPEVETVRRGLEQKLNNFIIKKVEVCRNSTVAFPTEKEEFIKGLQNSLLYKWDRRGKYLIAELKKIENENIKFPLKKLRQNNGFLVVHLRMTGYFKFIDNSTQPCKHTRIRVFDKKNNELRYIDVRSFGQMWWIKEGLSPNKIIKGLGSLGPEPFSKNFDEKYLKKVISKRKKSIKAILLDQTIVAGIGNIYADESLYSAGISPFRAAKTIKKNELINLKESIVNVLKKSIGSGGTTFSDFRDLEGENGNFGLQTNVYRRTGKECRKCGNLIEKQKIAGRSTHWCPNCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: Y6555_BACAN
Sequence: MTKVDKVKEKIIETSLYLFNTNGITRTSIQDIMTATELPKGSIYRRFKNKEEIVLAAYDKSGEIMWSHFHKAMENKKTAIDKILAIFLVYQDAANNPPIAGGCPLLNSAIESTGVFPELQKAAAKGYDDTVMLMASLIKEGIEKQELKEDIDIISLASFLASSMEGAIMASRVSNDNIHHQYFIEQIKHHLYSYSK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator pXO2-48/BXB0055/GBAA_pXO2_0055.