PharMolix/UniProtQA huggingface dataset:
Protein: AURG_CALAK
Sequence: MGLWLVLANQVGLVGTLVLVVCFTPANSLVRPLLLPGITALVSYGLILNKEAIANAGAWSLVNLNTAGLFLQYLDVGLISRWTYSAYGPTSSRGGQPNASLDLAGRKKPPSSSLLSRLQWGFSTATSWRAPSTVWEAKGTPHFEELPSRGRFLARNAMTLLWSVLVLDVMGLVGGDLDPVANAAHFTWDRVRFLARLGDVSRDEVILRATVVYMRWGAMYFSLQVVYSFLAIVFVMVGLSPVQRWPPLFGSFTEIYTLRNTWGKAWHQLIRQKVSSPAHYTTYSLLGLRKGGIAGRYTCILATFFVSGLLHLFCAEYSYGIQWDQSGTLRFYSIQALGIAMEDAVQATSRRLFAYRSTYWTRAIGYVWVLLWFLWTSPAYFFPLLKYDTEKRPPVLLGPIETWLQSRHVQ
What is the function of this protein?
Acetyltransferase; part of the gene cluster that mediates the biosynthesis of aurovertins, fungal polyketides that exhibit potent inhibition of adenosine triphosphate synthase (PubMed:26340065).  Tha biosynthesis starts with the HR-PKS aurA that selects propionate as the starter unit; synthesizes a hexa-ene chain through the repeated functions of the KR and DH domains in the first six iterations; selectively introduces three alpha-methyl substitutions at C4, C6, and C16 using the S-adensylmethionine-dependent cMET; and shuts off KR and DH in the last three iterations to afford a 1,3,5-triketo portion that can undergo intramolecular cyclization to yield the alpha-pyrone intermediate (PubMed:26340065).  AurE may act as a cyclase and enhances the rate of pyrone formation and product release of aurA (PubMed:26340065).  The methyltransferase aurB then methylates the C17 hydroxyl group (PubMed:26340065).  C17 methylation is required to initiate epoxidation by the downstream monooxygenase aurC (PubMed:26340065).  The monooxygenase aurC and the epoxide hydrolase aurD can iteratively transform the terminal triene portion of the methylated precursor into the dioxabicyclo[3. 2. 1]octane scaffold of aurovertin E.  Epoxidation modifications of the precursor occur in two separate steps; bis-epoxidation of the two terminal olefins takes place first, followed by another epoxidation that occurs at C7-C8 after tetrahydrofuran formation (PubMed:26340065).  The O-acyltransferase aurG converts aurovertin E to aurovertin A (PubMed:26340065).
What are the official names of this protein?
Acetyltransferase aurG, Aurovertin biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the wax synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ELOF1_BOVIN
Sequence: MGRRKSKRKPPPKKKMTGTLETQFTCPFCNHEKSCDVKMDRARNTGVISCTVCLEEFQTPITYLSEPVDVYSDWIDACEAANQ
What is the function of this protein?
Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.
What are the official names of this protein?
Transcription elongation factor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ELOF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECO_FRAP2
Sequence: MQQLYDFYILHQCKYKENSLLVSIFTREFGKISGLIRVNKKTINLYQPLVKLRGQISLAKKSDGLSKIYNVEFVESFYQNTYINLLSLQYMNELIYLLLSYSHEEEFLFEKYGFILKNINEINYKYLLRMFELELLDSLGQGVYVDCDIDGMLIDESLSYSILATGFKKNLSTIPNSIAGKNLLKINQSVSLWTDEDLKAISKVTRAYIDYALAGKQLRSRKLLIDYLNLGKK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TESB_HAEIN
Sequence: MSDILNNLIHLLKLEKIDDLIFRGESQDLGFRQVFGGQVVAQALSAAMQVAPEDRILHSCHAYFLAPGDSQYPIIYDVETLREGRNFSALCVKAIQHKNTICHVTASFQVPEKGFEHQNTMPNVGAPEDFTDENVMLQKVAQTLPEPLNEKFAAERPFEVRTKYLNNPFNGTKLPAEQYSWFKTNGETPLDIKIQQCLLAYFSDFHCILTALHPHEKGFLQKGMKVATIDHSIWFHRPFDLNHWHLHAIESNNAFGGRGLAQGQIFSQDGQLIATTQQEGLIRFSE
What is the function of this protein?
Thioesterase that has relatively broad substrate specificity, hydrolyzing primarily medium- and long-chain acyl-CoA substrates to free fatty acids and CoA.
What are the official names of this protein?
Acyl-CoA thioesterase 2, Thioesterase II, TEII.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
Protein: PUR2_VIBVU
Sequence: MNVLIIGSGGREHALGWKAAQNPNVETIFVAPGNAGTALEPKLENVNIAVEDIAGLVAFAKEKAIELTIVGPEVPLVLGVVDAFYEAGLPIFGPTQAAAQLEGSKAFTKDFLARHQIPTAAYANFTDIEPALAYVREQGAPIVVKADGLAAGKGVIVAMTLEEAEEAIKDMLAGNAFGEAGSRVVIEEFLDGEEASFIVMVDGENVLPMATSQDHKRVGDKDTGPNTGGMGAYSPAPVVTPEIHNRVMQEVIFPTVRGMAAEGNPYTGFLYAGLMIDKDGTPKVIEYNCRFGDPETQPIMMRMESDLVELCLAAIDKKLDQVESKWDPRASIGIVLAAGGYPAAYNKGDVISGLPQVEIEGEKVFHAGTENKEGDIVTNGGRVLCATALGNSVSEAQQRAYELAKQIRWEGMFHRNDIGYRAIAREQQK
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: SOPE_SALTM
Sequence: MTKITLSPQNFRIQKQETTLLKEKSTEKNSLAKSILAVKNHFIELRSKLSERFISHKNTESSATHFHRGSASEGRAVLTNKVVKDFMLQTLNDIDIRGSASKDPAYASQTREAILSAVYSKNKDQCCNLLISKGINIAPFLQEIGEAAKNAGLPGTTKNDVFTPSGAGANPFITPLISSANSKYPRMFINQHQQASFKIYAEKIIMTEVAPLFNECAMPTPQQFQLILENIANKYIQNTP
What is the function of this protein?
Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF).  This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells.  Also activates MAPK8, indicating that it is capable of stimulating signaling pathways that can lead to nuclear responses.  Chaperone InvB is required for secretion and translocation of SopE.
What are the official names of this protein?
Guanine nucleotide exchange factor SopE, Effector protein SopE, Toxin SopE.
What is the protein family that this protein belongs to?
Belongs to the GEF (guanine exchange factor) SopE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS).
Protein: DNAK_BACLD
Sequence: MSKVIGIDLGTTNSCVAVLEGGEPKVIPNPEGARTTPSVVAFKNGERQVGEVAKRQSITNPNTIMSIKRHMGTDYTVEIEGKKYTPQEVSAIILQHLKSYAESYLGETVSKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTEEDQTILVYDLGGGTFDVSILELGDGVFEVRSTAGDNRLGGDDFDQVIIDHLVSEFKKENGIDLSKDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGEAGPLHLELTLTRAKFEELSSHLVERTMGPVRQALQDAGLSASEIDKVILVGGSTRIPAVQEAIKKETGKEAHKGVNPDEVVALGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFSTAADNQTAVDIHVLQGERPMAADNKTLGRFQLTDIPPAPRGVPQIEVSFDIDKNGIVNVSAKDLGTGKEQNITIKSSSGLSDDEIERMVKEAEENAEADAKKKEEIELRNEADQLVFTTEKTLKDLEGKADEAQVKKANEAKDALKAAIEKNDLDEIKAKKDELQAIVQELSMKLYEEAAKQAQAQQDGGAGAKKADDNVVDAEYEEVNDDKDQK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: AROC_HAES1
Sequence: MAGNSIGQLFRVTTFGESHGIALGCIVDGMPPGLALSEDDIQPDLDRRKPGTSKYTTPRREEDKVQILSGVFDGKTTGTSIGMIIKNTDQRSQDYGEIKDRFRPGHADFTYQQKYGLRDYRGGGRSSARETVMRVAAGAIAKKYLREYFGIEVRGYLSQIGEIKIDPQVVADVSKIDWAKVNSNPFFCPDESAVEKFDELIRELKKAGNSIGAKLTIVAEHVPVGLGEPVFDRLDADLAHALMGINAVKAVEIGDGFAVVEQKGTEHRDEMTPEGFCSNHAGGILGGISSGQPIIATIALKPTSSITVVGRSVNLNNEPVDVITKGRHDPCVGIRAVPIAEAMMAIVLLDHLLRFKAQCK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: UL79_ALHV1
Sequence: MSTNPATNSESLDILGRYVSAGPGFSPGVRALLFKLLGGKTLNTLTPEELRFSHLVVSKMYELGLNVFLLREAVANCGVTDAVILERKVPVEFWKILFDGCVALGVKEDMLLSEAGRSQLWLHLNKNPQLLKGLAGYVLRRLGLCQHVKVHPQNLLDGNFLFNLGSVFSCRLLMVAAFCLLFWGRPEVEPWVRTFVTKIYVLYLIIVGALRINFSVFELSTQNGYCGILEAICSDLMAVAGHGGEGSRERQWHAWLDYLFIFNNNVVLHNSNRDG
What are the official names of this protein?
Gene 18 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL79 family.
Protein: MNME_CHLFF
Sequence: MIKNDTIAAIATPPGEGSIAIVRVSGPEAIQITDKIFSGPVPSFASHTAHLGTASHHGRQIDQVLLLIMRAPRSFTGEDVVELQCHGGYFSCSQILEALVSEGARPALPGEFSQRAFLNGKIDLIQAEAIQNLIAADNLDAFHIAQNHFQGHFSQRVQKISSLIIESLAFIEVLADFPEEEQPDMEVPEKRLNEALVIIEDLISSFDEGQRLAQGTSIVLAGHPNAGKSSLLNALTNRNRAIVTDIPGTTRDILEESWTLQGKRIRLIDSAGQRETDNPVEQEGIERAISAMKQAEGILWVMDATQPPPPLPEILFQKPSLLLWNKSDLASPPRIDTSLPQLAISAKTGDGILELKQFIQKWIQKQQLGKNSKVFLVSARHHTILQQIRTYLLSAKEGLLSQLPPELVALELRQALQTTGNLSGSEINETILGEIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_PSEA7
Sequence: MTAVFDASAFLATCSNRPGVYRMFDADAKLLYVGKAKSLKKRLASYFRKSGLAPKTAALVVRIAQVETTITANETEALLLEQTLIKEWRPPYNILLRDDKSYPFVFLSSEDEYPRLSLHRGAKKRKGRYFGPYPSAGAIRESLNLLQKAFLVRQCEDSYFRNRTRPCLQYQIKRCKGPCVGLVGPEEYAEDVRHSVMFLEGRSNALADELNTGMEQAAMRLDFEKAAELRDQVAILRRVQDQQSMEGGNGDVDIVAAIVTPGGACVHLISVRGGRVLGSKNFFPQVAIEEEVGEVLLAFLGQYYLSHQERDLPAELIVNVMHEDFPVLVAAIAEARGRQLEISYRVRGTRARWQQLAVTNAEQALGARLANRQHVAARFEALAEALDLAEPPQRLECFDISHSSGEATVASCVVFGPEGPLKSDYRRYNIEGVTAGDDYAAMHQALTRRFSRLKEGEGKMPDILLVDGGKGQLAMAQEVLQELAVAGLILLGVAKGVTRKPGLETLYLNDAAHEFTLPADSPALHLIQQIRDEAHRFAITGHRARRGKARRTSTLEDVPGVGPKRRRDLLKHFGGLQELSRASIDELAKAPGISKKLAEQIYAVLHSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSP9_PLAFF
Sequence: HYKKRKAQEKGLPEPTVTNEEYVEELKKGILDMGIKLLFSKVKSLLKKLKNKIFPKKKEDNQAVDTKSMEEPKVKAQPALRGVEPTEDSNIMNSINNVMDEIDFFEKELIENNNTPNVVPPTQSKKKNKNETVSGMDENFDNHPENYFKEEYYYDENDDMEVKVKKIGVTLKKFEPLKNGNVSETIKLIHLGNKDKKHIEAINNDIQIIKQELQAIYNELMNYTNGNKNIQQIFQQNILENDVLNQETEEEMEKQVEAITKQIEAEVDALAPKNKEEEEKEKEKEKEKEEKEKEEKEKEKEEKEKEEKEKEEKEEKEEEKK
What is the function of this protein?
During the asexual blood stage, involved in the sialic acid-independent (SAID) merozoite invasion of host erythrocytes by binding to host SLC4A1/Band 3 protein on the surface of the host erythrocyte.
What are the official names of this protein?
Merozoite surface protein 9, 101 kDa malaria antigen, Acidic basic repeat antigen, p101 protein.
What is the protein family that this protein belongs to?
Belongs to the plasmodium ABRA family.
Protein: RK14_LEMMI
Sequence: MIQPQTLLNVADNSGARELMCIRILGASNRRYANIGDVIVAVIKEAVPNMPLERSEVIRAVIVRTRKELKRENGMRIRYDDNAAVVIDQEGNPKGTRVFGAIARELRELNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYGA_FRAP2
Sequence: MLTFQEIILKLHHYWASKGCAIIQPLDMEVGAGTFHPATTLRAIGPEPWTAAYVQPSRRPTDGRYGENPNRTQHYYQYQVVMKPSPDDIQELYLGSLRELGIDPLENDIRFVEDNWESPTLGAWGLGWEVWSNGMEITQFTYFQQVGGLECKPVMGEITYGLERLAMYIQNVDSMYDILWANTQNGPLYYRDVFLQNEIEMSTYNFEEANVEELFKQFDLLEKEGYRLVGKNLPIPAYEFVLKASHTFNLLDARHAISVTERQGYILRVRKLALEVAKEYYSAREKLGFPAFKKNN
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_DELAS
Sequence: MTTLGTPYSPHATKVMLLGSGELGKEVLIALQRLGVETIAVDRYENAPGQQVAHHARTITMSDPAQLKALIEAEKPDLVVPEIEAIATPMLEELEAAGVVTVIPTARAARLTMDREGIRRLAAETLGLATSPYRFCDSQQELQAAIDGTDGQPAIGFPCVVKPVMSSSGKGQSKLDGPDDVAKAWDYAMAGGRVSHGRVIVEGFIDFDYEITQLTVRAKGADGQVQTHFCDPIGHIQQSGDYVESWQPHPMHPAALQKSRDIAKAVTDDLGGLGLFGVELFVKGEQVWFSEVSPRPHDTGLVTLATQWQSEFELHARAILGLPVDASLRNPGASAVIYGGQDAEGLVFDGVDEALAVPGTDLRLFGKPESFVKRRMGVALARAQDVEQARTNAKLAAGKVKPRKP
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: REV_HV192
Sequence: MAGRSGDSDEALLQAVRIIKILYQSNPYPKPEGTRQARRNRRRRWRARQRQIHSISERILSTCVGRPAEPVPFQLPPIERLNINCSESGGTSGTQQPQGNTERVGNP
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: WRT1_CAEEL
Sequence: MMVMNPLTATFLAALIGTAASASCGSSGIPFRFEVLPSGQPVLGCGSPTCFGAENGGRDLRHDSSFMAGADGDDGFFRDGDLARVRVRDPDAPAQMANCPREFSSSSCSNPMTWVGGFKASDNGDLSLQCCHYEGLRFAQEVGRPVVHPGEVYSGGEVLRDGRQTGFDAISNVRKITSGDGTVAYEVTVTRMNCLPNPGEESNEVSFDIQRDIGRILDKVGETAASGVQTNHIEADQRLSPSTDVQSDSYVSPTEADPQEPVEQFVQVGEQVVPVTSAGYYYPVASGVPACFTGNSKVMTPAGEKSMADLSVGDMVMTYEYGKMTYTRVASWLHRLPDTKAAFIKLTTEQGAIIDMTPQHFIYKANCVTEEMELVYAEDMTIGDCLMVKENEKLVMTTISEKSTFYETGVYAPMTETGDLIVDDVYASCHNVVKANTLSHTFLNFATSVQQKMRSVLGSLEETGHLPATSEFFLNIIDVLLPHKY
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.
What are the official names of this protein?
Warthog protein 1.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
[Warthog protein 1]: Secreted. Cell surface. Note=Also secreted in either cleaved or uncleaved form to mediate signaling to other cells. SUBCELLULAR LOCATION: [Warthog protein 1 N-product]: Cell membrane; Peripheral membrane protein; Extracellular side. SUBCELLULAR LOCATION: [Warthog protein 1 C-product]: Secreted, extracellular space. Note=Also secreted in either cleaved or uncleaved form to mediate signaling to other cells.
Protein: NDHM_SYNS3
Sequence: MADTLLKSTTRHVRLFTARVNEGRLVPDPNQLTLDLDPDNEFLWNDSCIQTVQQRFRELVEAHAGQPLNDYNLRRIGSELEGSIRQLLQAGQLSYNPDCRVLNYSMGLPRTPELL
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit M, NAD(P)H dehydrogenase I subunit M, NDH-1 subunit M, NDH-M.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhM subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLMF_ENT38
Sequence: MTAEKPGLHPRNRHRSRYDMNALCQSCPQLQAFIVQTPAGEPSVNFADPLAVKALNKALLAHFYGVTQWDIPEGFLCPPVPGRADYVHHLADLLAEDNAGTIPPQATVLDIGTGANLIYPLIGVAEYGWRFTGSETGKDAYASAQAIVNGNEGLTRAIRLRRQKEASDIFNGIIHKNESYDATMCNPPFHDSAETARAGSERKRRNLGQAEDGALNFGGQQHELWCEGGEVAFIEKMIAESKLFARQVKWFTTLVSRGDNLPPLYRALTAVGAVKVVKKEMAQGQKQSRFIAWTFMDDAKRRKSF
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_RICTY
Sequence: MSKKLYIKTYGCQMNVYDSVKIQDLLYPFGYESTEDIKEADIIILNTCHIREKAAEKTYSELGRIKKLQNTRKQEGLNPAIIVVAGCVAQAEGEVIFTRTPYVDIVVGPQSYYNLPELISKVVRHEKHLIDLDFVEEAKFDNLPEQLYTQGASSFISVQEGCDKFCTFCVVPYTRGAEFSRSVEQVYRESLKVVSNDTKEIILLGQNVNAYHGKGPKDKIFTLADLLKHLAQIPNLERLRYMTSHPIDMTDDLIKLHGTEPKLMPFLHLPVQSGSNKILKAMNRKHDRDYYFNIINRLREARSDIVLSSDFIVGFPGETEKDFEDTLDLVQRVKYGQCYSFKYSPRPGTPGAIRTDQIPEHIKSKRLTILQKELATQQLAFNESCVGSTMKVLFDRDGKFEDQIIGKTPYMQSVYIHNPNKSLLGKIVDVIITKAALNSLTGEIL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF1_PSESM
Sequence: MAILNILEFPDSRLRTLAKPVAMVDDGIRQLVDDMFETMYEAPGIGLAATQVNVHKRVVVMDLSEDRSAPMVFINPEIEKLTDEMDQYQEGCLSVPGFYENVDRPQKVRVKALDRDGKPYELVAEGLLAICIQHECDHLNGKLFVDYLSNLKRDRIKKKLEKQHKLNA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RS4_HISS2
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIDTAPGQHGARKPRLSDYGSQLREKQKVRRIYGILERQFRNYYKEANRLKGNTGENLLVLLEGRLDNVVYRMGFAATRAEARQLVSHKAIVVNGRVVNIPSFQVSVNDVVAVREKSKKQARIKASLELAEQREKPTWLEVEAAKMEGVFKRVPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CWP30_ARATH
Sequence: APQEPNQFQLLKYH
What are the official names of this protein?
33 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: Y318_RICPR
Sequence: MNIYAIYINSTQKNNNFIILEEGFSWIAALFSIFWALYHKMWIVVAITVIANIIATTIIVDFKFIFQIFLILSFGFFAADIRENYLNRNNYQLEDIIIANSRIEAELKFLERSILI
What are the official names of this protein?
Uncharacterized protein RP318.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MIC13_MACFA
Sequence: MVARVWSLMRFLIKGSVAGGAVYLVYDQELLGPSDKSQAALQKAGEVVPPAVYQFSQYVCQQTGLQIPQLPAPPKIYFPIRDSWNAGIMTVMSALSVAPSKAREYSKEGWEYVKARTK
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology.  Required for the incorporation of MICOS10/MIC10 into the MICOS complex.
What are the official names of this protein?
MICOS complex subunit MIC13, Protein P117.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic13 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=Enriched at crista junctions.
Protein: SYS_TREDE
Sequence: MLDYKFIKENVEAVKQNIKNRHMNADADKAVELYDKRTALVTSLQNLQKDRNDNSQSMKQKLSPEERQKLVDQGKAIKEKIAQVEAELAEAEKALHEAVSKIPNMAHPEAPVGKEDSDNLEVKRCGTVPKFDFEPKDHVQLGQDLDLIDFEAGTKVSGVKFYFLKNEAVFLEQALTMYGLNILRKHGFKPFITPDIAKEEILYGIGFNPRGEESNVYSLEGEGTCLVATAEITLGGYHSDEIIKKESLPLKYCGLSHCFRREAGAAGQFSKGLYRVHQFSKLEMFVYCTPEESDALHEELRLIEEEIFNGLGIPFRVVDTCTGDLGAPAYRKWDLEAWMPGRNGGEWGEVTSTSNCTDYQARRLNIRYKDDDGKNKFLHTLNGTALAMSRAMIAVLENYQQADGSIKIPEALVPYCGFDRIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.