PharMolix/UniProtQA huggingface dataset:
Protein: PRO_BPLSK
Sequence: MKLITNSAEIKVTENEDGSKSFQGIGSEVGVENRNGIVLTPNCIEFARERYPLLYEHGAGSSEVIGDAKVYYDLASNKYLTDFTLYDNAPNINKAVENGAFDSLSIAYYITDYEFNENDALVVNKAQFKEISLVSVPADPNAKFIQNALGEELTEERNKIIESRNALKEIEDIKKKYE
What is the function of this protein?
Probable capsid maturation protease.
What are the official names of this protein?
Probable capsid maturation protease, Gene product 5, gp5.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus capsid maturation protease family.
Protein: RHAB_ECO5E
Sequence: MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLMPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALISATQALPACRFIINPNDDRFINPETMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVARIHSTRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: VM2AB_AGKCO
Sequence: MIQVLLVTLCLAAFPYQGSSIILESGNVNDYEVLYPQKVIALPKGAVQPKYEDTMQYEFKVNGEPVVLHLEKNKGLFSKDYSETHYSSDGRKITTNPPVEDHCYYHGRIQNDADSTASISACNGLKGHFKLQGETYLIEPLKLPDSEAHAVYKYENVEKEDEAPKMCGVTQTNWKSDKPIKKASQLNLTPEQQGFPQRYIELVVVADHRMFTKYNSNLNTIRIWVHELVNTMNVFYRPLNIRVSLTDLEVWSNRDLINVQPAAADTLEAFGDWRETVLLNRISHDNAQLLTAIELDGETIGLANRGTMCDPKLSTGIVQDHSAINLWVAVTMAHEMGHNLGISHDGNQCHCDANSCIMSEELREQLSFEFSDCSQNQYQTYLTDHNPQCMLNEPLRTDIVSTPVSGNELLETGEESDFDAPANPCCDAATCKLTTGSQCADGLCCDQCKFMKEGTVCRRARGDDLDDYCNGISAGCPRNPFHA
What is the function of this protein?
Inhibits platelet aggregation in human platelet-rich plasma induced by ADP.  Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIe sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPE_ANAMF
Sequence: MQGVMSKYQINAPAKINLFLHVVGKSTSGYHVLESVFAFIKLYDTLEIEIGSKNRGVEFVQFSGISKHDNTVQRAIGHLVRRCAPGVAKNVYVKVTKNIPVSAGLAGGSADAAAIIRLLGKNWGISEAGMNGVAASVGSDVPVCLQSRTAFVCGMGENVKLLPHARLPNYVVLVRPNDVYLSTRSVFDAYACKEFSKSIGNPPEASDGLLSLVMQSRNDLTDTAILLVPEVKKILAELQSLGGCILSRMSGSGATCFALFEDGEAASDGVRYLKGRHPEWWVYETEISQ
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RS17_BACLD
Sequence: MSERNQRKVYQGRVVSDKMDKTITVVVETYKKHSLYGKRVKYSKKFKAHDENNQAKIGDIVKIMETRPLSATKRFRLVEVVEEAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DC121_HUMAN
Sequence: MAQQQTGSRKRKAPAVEADAESSPSQGLAAADGEGPLLLKRQRRPATYRSMAHYLKVREVGGWGPARLQGFDGELRGYAVQRLPELLTERQLELGTVNKVFASQWLNSRQVVCGTKCNTLFVVDVESGHIARIPLLRDSEARLAQDQQGCGIHAIELNPSKTLLATGGENPNSLAIYQLPSLDPLCLGDRHGHKDWIFAVAWLSDTVAVSGSRDGTVALWRMDPDKFDDTVAWHSEVGLPVYAHIRPRDVEAIPRAIINPSNRKVRALACGGKNQELGAVSLDGYFHLWKAGSALSRLLSIRLPYFRDNVCLTYCDDMSVYAVGSHSHVSFLDLRQDQQNIRPLCSREGGTGVRSLSFYRHIITVGTGQGSLLFYDVRAQKFLEERASATLESSSGPARRKLRLACGRGWLNHNDFWVNYFGGMEVFPNALYTHCYNWPEMKLFVAGGPLPAGLHGNYAGLWS
What are the official names of this protein?
DDB1- and CUL4-associated factor 12-like protein 1, WD repeat-containing protein 40B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF12 family.
Protein: RS6_BURCM
Sequence: MRHYEIVFIVHPDQSEQVPAMIERYKTTITTHGGQIHRVEDWGRRQLAYMIEKLAKAHYVCMNIECDQTTLDELEHAFKFNDAVLRHLIVKMKKAETGPSPMMKEVQREEAKKAAAAQPTEAQA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TATA_MYCTO
Sequence: MGSLSPWHWAILAVVVIVLFGAKKLPDAARSLGKSLRIFKSEVRELQNENKAEASIETPTPVQSQRVDPSAASGQDSTEARPA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PYRG_STAAN
Sequence: MTKFIFVTGGVVSSLGKGITASSLGRLLKDRGLNVTIQKFDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKFSNVTAGKVYSHVLKKERRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIESLPFIEAIRQIRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELRGLGIQPDLIVVRTEYEMTQDLKDKIALFCDINKESVIECRDADSLYEIPLQLSQQNMDDIVIKRLQLNAKYETQLDEWKQLLDIVNNLDGKITIGLVGKYVSLQDAYLSVVESLKHAGYPFAKDIDIRWIDSSEVTDENAAEYLADVDGILVPGGFGFRASEGKISAIKYARENNVPFFGICLGMQLATVEFSRNVLGLEGAHSAELDPATPYPIIDLLPEQKDIEDLGGTLRLGLYPCSIKEGTLAQDVYGKAEIEERHRHRYEFNNDYREQLEANGMVISGTSPDGRLVEMVEIPTNDFFIACQFHPEFLSRPNRPHPIFKSFIEASLKYQQNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NAGK_RALSP
Sequence: MGRPVDKSVEQAFYFTKSPQTLVESGATVAYPPRTSNYHYEMELVLAIGKPGFRVSEDQAHELIYGYAAGLDMTRRDLQLVARDKGRPWDTGKDIEEGSVCSEIVPMQGVVVEQGAIALEVNGQTKQSSNVDKLIWNVREIIADLSTYYHLQPGDLIYTGTPEGVGAVVAGDKIIGRVEGIAEISLTVGPAE
What is the function of this protein?
Involved in the catabolism of gentisate (2,5-dihydroxybenzoate) a key intermediates in the aerobic pathways for the metabolism of a large number of aromatic compoun such as naphthalene.  Catalyzes the hydrolytic cleavage of fumarylpyruvate to form fumarate and pyruvate.
What are the official names of this protein?
Fumarylpyruvate hydrolase, Naphthalene degradation protein K.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: RS13_STRP8
Sequence: MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIRVKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNTKNNARTRKGKAVAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RS8_STRP8
Sequence: MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREGFVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLGIAIISTSEGLLTDKEARQKNVGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PYRB_SYNS3
Sequence: MSGWSHRHVLDLASFSRDDYATVLELAHRFRSMPVTGARKLPALQGRLVATLFFEPSTRTRSSFELAAKRLSADVQSFSPSSSSLSKGESLLDTARTYVAMGADVLVIRHRCTDVPAQLASELDQAGERTVVLNGGDGQHSHPSQGLLDLYTLAHHFDPRNSQLDALQGKRIVIVGDVVHSRVARSNLWALSACGADVVLCGPPSLVPDAFAAFLDAPPPGQASDPVRERGTVQISRSLDDCLSGADAVMTLRLQKERMTDHLLTNLDRYHRDFGLTHERLRRCAFSGPVLHPGPVNRGVEMSGGLLDDRSICLVEDQVRNGIPIRMALLYLMAASDPVAESSRASAPS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GUMK_XANCP
Sequence: MSVSPAAPASGIRRPCYLVLSAHDFRTPRRANIHFITDQLALRGTTRFFSLRYSRLSRMKGDMRLPLDDTANTVVSHNGVDCYLWRTTVHPFNTRRSWLRPVEDAMFRWYAAHPPKQLLDWMRESDVIVFESGIAVAFIELAKRVNPAAKLVYRASDGLSTINVASYIEREFDRVAPTLDVIALVSPAMAAEVASRDNVFHVGHGVDHNLDQLGDPSPYAEGIHAVAVGSMLFDPEFFVVASKAFPQVTFHVIGSGMGRHPGYGDNVIVYGEMKHAQTIGYIKHARFGIAPYASEQVPVYLADSSMKLLQYDFFGLPAVCPNAVVGPYKSRFGYTPGNADSVIAAITQALEAPRVRYRQCLNWSDTTDRVLDPRAYPETRLYPHPPTAAPQLSSEAALSH
What is the function of this protein?
Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid-beta-mannose linkage.  Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P-polyisoprenyl repeating unit of xanthan.
What are the official names of this protein?
UDP-glucuronate:glycolipid 2-beta-glucuronosyltransferase, UDP-GlcA:glycolipid glucuronosyltransferase, D-man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphosphoundecaprenol 2-beta-glucuronyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 70 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FAU1_SULIM
Sequence: MKGRVRIRGIYATALTSIFSSLSYEIVQQSVEIAERFMREVNNLPADITIKDFEYDRGKIIVMGNGTIEEDLHDVFKYSFHWKSPIKLYSVIEADESCTYGNFKVEPCLEEGIVIKPPYDGKIVLSETKAVSKYAMVWRGKGVTTFSEHINNEEERLRLLTLSSPLNRKGYNVKWRSNAKYATLNELKEDLERLVLRYENREFRDQGEDFYLITLSLPDKLHLDEVRKSIVNTVKYHHMLKLSYNREVDSLEKDKEGSPVKLLEALISDFMKIEHIKADGKAIYLRGGKVIEKEVNNDGYRITLRREINGNGVLDGIGKRIENGDYDIVEYNSDKWYQIHRYYSGIDNSLKGIYINISTPPELLKGKIRYLDLEIDIAIRDSEIIVLDEDELNKKSIYMHSSLVNKAKEVANYLIDCIQQNKLI
What is the function of this protein?
Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs.  Binds to RNA in loop regions with AU-rich sequences.
What are the official names of this protein?
Probable ribonuclease FAU-1, RNA-binding protein FAU-1.
What is the protein family that this protein belongs to?
Belongs to the FAU-1 family.
Protein: ISPE_THEP1
Sequence: MVENIGNGSAELVSYAKLNLYLDVLGKRSDEYHEIVGLFQTISLHDTLTVEICDGGFYLESNVALPSDNTIKRAWEMFRKNTGEEFGLKVTLKKKVPVGSGLGGGSSNAAAILRYLGEVFKIPLEDLLNIAAQVGSDVPFFLYGGTALVRGRGEIVEKLEDIEGYSVNLFFPGIHSSTKEMYLSLTPEMYRKGPGRVEELHRAYLERDYEKIRKLSYNVFEKVFLEKHPEVMYGLRNFGDGSIVKMMTGSGSAFFALYPLDEGNYPFVGGV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: LBH_XENTR
Sequence: MSVFYPIHCTDYLRSAEMTEVIMNTQPMDEIGLSPRKDSYQIFPDPSDFERCCKLKDRLPSIVVEPTEGDVESGELRWPPEEFVVDEDKEGSCDQTKKENEQ
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Protein LBH.
What is the protein family that this protein belongs to?
Belongs to the LBH family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RF1_SALPB
Sequence: MKPSIVAKLEALHERHEEVQALLGDAGIIADQDRFRALSREYAQLSDVSRCFTDWQQVQDDIETAQMMLDDPEMREMAQEELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSMSEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPEAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAETAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDETMEGKLDMLIEPIVQEHQADLLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EME1_PONAB
Sequence: MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAPGLLSPPVPDIAETVTQTQPVRLLSSGSEDEEEFIPLAQRLKCKFLTHKQLSPEDSSSPIKSVLDHQNNEGASCDWKKQPFPKIPEVPLHDTLERSAADNKDLILDPCRQLPACLSTCPGQSSSLAVTKTNSDILPPQKKTKRSQKVQGRGSHGCRQQRQARQKESTLRRQERKNAALVARMKAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQSMECRCVIEAQAVPCSVTWRRRAGPSEVLWQDGEDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITARTAGKALSLVIVDQEKCFSAQNPPRRGKQGANKQTKEKQQRQPEASIGSMVSRVDAEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEVPFKKLRDETTFSFCVESDWAGGVKVDRAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYRQCFSEQERQNLLADIQVRRGEGVTSTSRRVGPELSRRIYLQMTTLQPHLSLDSAD
What is the function of this protein?
Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions.  May be required in mitosis for the processing of stalled or collapsed replication forks (By similarity).
What are the official names of this protein?
Crossover junction endonuclease EME1.
What is the protein family that this protein belongs to?
Belongs to the EME1/MMS4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Recruited to regions of DNA damage in S-phase cells.
Protein: SUB4_ARTBC
Sequence: MVCLKTLSVFLAAFAAADARAVFKTQGHKNSEMIPDNYIVVMKDGVSQDDFKAHISSVASIHSTNKAKRGTNTQGMKREFDIMNWRGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRSAPSWGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDNADRHGHGTHTASTFAGTAYGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQDAQQRGILGKAAMNLSLGGGFSQANNDAVTRAQNAGIFVAVAAGNDNRDARNYSPASAPAVCTVASSTINDSKSSFSNWGPVVDIYAPGSDIIAARPGGGSTTMSGTSMASPHVAGMGAYMIGMGADPRQVCDRLKQLATAAIRNPGSSTTNRLLYNGSGQ
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSTT2_RAT
Sequence: MGLELYLDLLSQPSRAVYIFAKKNGIPFQLRTVDLLKGQHLSEQFSQVNCLKKVPVLKDGSFVLTESTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTKVLGPLIGVQVPEEKVERNRNSMVLALQRLEDKFLRDRAFIAGQQVTLADLMSLEELIQPVALGCNLFEGRPQLTAWRERVEAFLGAELCQEAHNPIMSVLGQAAKKTLPVPPPEAHASMMLRIARIP
What is the function of this protein?
Catalyzes the inactivation of reactive sulfate esters in carcinogenic arylmethanols (PubMed:2114406).  Highest activity towards ethacrynic acid and cumene hydroperoxide (PubMed:2114406).
What are the official names of this protein?
Glutathione S-transferase theta-2, GST 12-12, GST class-theta-2, Glutathione S-transferase 12, Glutathione S-transferase Yrs-Yrs.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: ACSA_BRADU
Sequence: MSEKIYDVPAEWAKRAWVDQAKYKEMYARSISDPNGFWAEQAKRIDWMKAPTKIENVSFAPGNVSIKWFEDGVLNVAHNCIDRHLHKRANQTAIIWEGDDPSQSRHITYKELHDEVCRMANILRTRNVKKGDRVTIYLPMIPEAAYAMLACARIGAIHSVVFAGFSPDSLAQRINDCQSKVIITADEGLRGGKKVPLKANVDAALAKADGVDWVVVVKRTGGKIDMNPTRDLWYHEAAAMVTTECPVEHMHAEDPLFILYTSGSTGQPKGVLHTSAGYLVYAAMTHQYVFDYHDGDIYWCTADVGWVTGHSYILYGPLANGATTLMFEGVPNYPDNSRFWNVIDKHKVNTFYTAPTAIRALMQGGDEPVKKTSRASLRLLGSVGEPINPEAWEWYHRVVGEDRCPIVDTWWQTETGGILITPLPGATKLKPGSATQPFFGVVPEIVDADGKVLEGETTGNLCLTRAWPGMMRTVYGDHARFEQTYFSTYKGKYFTGDGCRRDADGYYWITGRVDDVINVSGHRMGTAEVESALVAHEKVSEAAVVGFPHDIKGQGIYAYVTLMAGVQPTEDLRKELVTWVRKEIGPIASPDQIQFAPGLPKTRSGKIMRRILRKIAEDEPGSLGDTSTLADPAVVDDLVKNRQNKKSA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ATP6_ORITB
Sequence: MLANPLSQFLIKPIIPLKALGYNISITNSAVAMIFVSIAASLLLIIAFVNSKLVPSRWQAFGEILYESNIKLVHSIIGPQGKVFFPLILTLFLFISLGNIIGMVPHAFTFTSHIIVTFSLAMIVFTTTLVYGIYRHKLGFFSLFLPKNIPLWLAPIMVIIELCVFISKPISLSLRLTANMVAGHILLKIIAWSIVSLTWFFKPLPIALVIVLIGFELFISILQAYIFTILSCVYLRDVVNLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATA_METMA
Sequence: MEVKGEIYRVAGPVVTAIGLDAKMYDLCKVGNEGLMGEVIQIVGDKTIIQVYEETGGVRPGEPCVTTGMSLAVELGPGLLSSIYDGVQRPLHVLLERTGGFIGRGVTADGLDHKKLWEFKPVVKKGDRVIGGDVIGVVQETVNIEHKIMVRPDISGTVADIKSGSFTVVDTICTLTDGTELQMMQRWPVRKPRPVKRKLTPEKPLVTGQRILDGLFPVAKGGTAAIPGPFGSGKTVTQQQLSKWSDTEIVVYIGCGERGNEMADVLWEFPELEDPQTGRPLMERTILVANTSNMPVAAREASVYTGMTLAEYFRDMGYDVSLMADSTSRWAEAMREISSRLEEMPGEEGYPAYLSARLAEFYERAGVAETLCGEKGSITAIGAVSPPGGDFSEPVTQNTLRIVKVFWALDAKLSQKRHFPAINWLNSYSLYKEDLNDWFTENVAPDYVPMRERAMDMLQTESELQEIVQLVGSDALPEEQQLLLEITRMIREIFLQQNAFHPIDTYSPFEKQYKIMKAIMKWGDAAMDALKSGVLSSEILKMQSKDELPKVKFEEDFEGSLNAVLAKMDKEFAALGGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: GUF1_ASPCL
Sequence: MRGCLQLARWLSAAPKGTAASLTRAPFGLANATRFFTNSAARAGSRATASKPVTDLENRISAIPIERYRNFCIVAHVDHGKSTLSDRLLELTGTIQPGSNKQVLDKLDVERERGITVKAQTCTMIYNHNGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGVQAQTVANFYLAFAQGLELIPVINKVDLPSAEPQRALDQMKHTFELDTENAVMVSAKTGLNVEQLLPTVVDKIPAPIGDCKKPLRMLLVDSWYDSYKGVICLVRIFDGELRAGQQVVSFATGLKYYVGEVGIMYPNETAQSVIRAGQVGYIYFNPGMKRSQEAKIGDTFTKVGSEKAVQPLPGFEEPKAMVFVAAYPVDADHFEHLEDSINQLVLNDRSITVQKESSEALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPSVPVKVIWTDGKEEIITSPVRFPDDEEVRNKIAEIQEPYVLATLTFPEEYLGKVIELCEANRGEQKTLEYFTATQVILKYELPLAQLVDDFFGKLKGSTKGYASLDYEESAWQPGHIVKLQLLVNKAPVDAVARIMHSSQVDRLARQWVTKFKQHVDRQLFEVVIQAAVGRKVIARETVKPYRKDVLAKLHASDVSRRRKLLEKQKEGRKRLRAVGNVVIEHKAFQAFLAK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor guf1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase guf1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SAHH_ACISJ
Sequence: MSAVLKSPADSAIADISLADWGRKEIRIAETEMPGLMAIREEFAAKQPLKGARITGSLHMTIQTAVLIETLKALGADVRWASCNIFSTQDHAAAAIAATGTPVFAIKGETLVDYWDYTHRIFDFGPKGSEGEGPNMILDDGGDATLLMHLGKRAEKDASVLAHPGSEEERILFAAIKAKLAEDSTWYSRKSAQIIGVTEETTTGVHRLKEMSAKGTLLFRAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKVAVVAGYGDVGKGSAQALRALSAQVWVTEIDPINALQAAMEGFKVVTMEWAADKADIFVTTTGNRDVITFEHMKAMKDQAIVCNIGHFDNEIQVAKLEEHCQWEEIKPQVDHVIFPDGKRIILLAKGRLVNLGCGTGHPSFVMSNSFANQTIAQIELFTHPEGYDVGKVYVLPKHLDEKVARLHLKKVGAMLTELSDEQAAYIGVPKQGPYKPDTYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTHB2_ONCMA
Sequence: MLGLHVGTLISLSLCILLEPVEGSLMQPCQPINQTVSLEKEGCPTCLVIQTPICSGHCITKEPVFRSPFSTVYQHVCTYRDVRYEMIRLPDCPPWVDPHVTYPVALSCDCSLCNMDTSDCTIESLQPDFCITQRVLTDGDMW
What is the function of this protein?
Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Gonadotropin subunit beta-2, GTH-II-beta, Gonadotropin beta-II chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_BRUO2
Sequence: MAQLIDGKKLAEDVVSTVKTETEKLVAATGVVPGIAVVIVGEDPASQVYVASKSRKAKECGFHSVQHDLPETASEQELLNLIEGLNNDPAIHGILVQLPLPGHIDSGRVIQTIAPEKDVDGFHFINVGKLGTGEVETAFVPCTPAGAMIMIERVHGRDLSGLNAVVIGRSNIVGKPMFNLLLAANATVTVAHSRTKDLPAIARNADILVAAVGRPQMVKGDWVKPGATVIDVGINRIPAPERGEGKTRLVGDVDFAEAEKVAGAITPVPGGVGPMTIAMLMANTLTAACRSAGMKKPVF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ISPF_KLEP7
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLRKADK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SFSA_SULTO
Sequence: MIVYSFPTLYEEIVKARINRFTVVTESEKICHLHDPGRLKELIYPGNKILIRNVNGKRKTNCQVTAAWSGKEWVVTDSSIHNEIARRFLPSDAKSEVTVGKSRIDFAFDNTYVEVKGCTLARDGIALFPDAPTKRGKRHLDELIELRRNGYSVLLMILVFRTDVVCFSPNFDTDRDFSNTFIKALKEGVNVEVKVFQLDKENIVYKGEIPVCHQILEKSTNFSLP
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.