PharMolix/UniProtQA huggingface dataset:
Protein: ADH_STAAN
Sequence: MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMEKGTITGRMVIKF
What are the official names of this protein?
Alcohol dehydrogenase, ADH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: ARLY_ROSDO
Sequence: MTDTQNPKSSNQMWGGRFADGPDAIMEAINASIGFDKRMAAQDIAGSRAHAAMLGATGIVEPSDAQAMGEGLLTVLSEIEAGNFPFSTALEDIHMNVEARLKEIIGEPAGRLHTGRSRNDQVATDFKLWVRDQLDACEAGLLALIRALLDQAEAGADWVMPGFTHLQTAQPVTWGHHMMAYVEMFGRDLSRVRDARARMNESPLGAAALAGTSFPIDRHMTAQALGFDRPAANSLDAVSDRDFALEFLSTASICAMHLSRFAEELVIWSSAQFRFVALSDRFSTGSSIMPQKKNPDAAELIRAKVGRIFGANTALMMVMKGLPLAYSKDMQEDKEQVFDAADNLMLALAAMTGMVSDMTANRESLAQAAGSGFSTATDLADWLVRVLGLPFREAHHVTGALVALAEAKHCDLPDLTLEDMRGVHAGITGDVFDVLGVENSVQSRISYGGTAPVRVREQIARWRALL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_LYCSM
Sequence: MFITRWLFSTNHKDIGTLYLLFGAWSGLIGACLSILMRMELTQPGSLLGSDQIFNVLVTAHAFIMIFFMVMPIMIGGFGNWLIPLMIGAPDMAFPRMNNMSFWLLPPALLLLLSSSYVEAGAGTGWTVYPPLSGNLVHSGPSVDLAIFSLHLAGASSILGAINFITTCINMKPKSMPMFNMPLFVWSVLITAIMLLLALPVLAAAITMLLTDRNLNTSFFDPCGGGDPVLFQHLFWFFGHPEVYILILPGFGIISSIITFYTGKKNTFGYTSMIWAMMSIAILGFVVWAHHMFTVGLDIDSRAYFTAATMIIAIPTGIKVFGWLATLAGGQIKWQTPIYWALGFIFLFTVGGMTGIILANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGLTHWFPLFTGYTLNQTMTKTQFWVMFVGVNMTFFPQHFLGLSGMPRRYSDFPDAFTLWNTMSSIGSTISMVAVLMSLFIVWEALTCKREVQMPLGKKTHVEWFFGSPPPYHTHTEPSFMLNNTYAPIRNLISYMEWPWPEK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y111_NPVAC
Sequence: MDNYSVQNFYNNDRKPLKPTTLHDGNIKKSVYEDVTYIRKLMCKEIMPGEHDHKFYNYGYNKENKYK
What are the official names of this protein?
Uncharacterized 8.2 kDa protein in HE65-PK2 intergenic region.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae 8 kDa protein family.
Protein: UREF_CITK8
Sequence: MTDARQRLRLMQLASSSLPVGSFTWSQGLEWAVEIGWVKNAEDFAHWQTQQLEQNFFTVDLPIFARLYHACERNDVTAARRWSAYLLACRETRELREEERSRGAAFTRLVVDWVPDCPQTWRPLFANSQLCGMAWLGVRWRIPLTDLALSLGYSWLESAVMAGVKLVPFGQQAAQQLILSLCDHYAQGMAQALARPDADLGSSTPLAAIASARHETQYCRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_THEMA
Sequence: MMAYLVFLGPPGAGKGTYAKRLQEITGIPHISTGDIFRDIVKKENDELGKKIKEIMERGELVPDELVNEVVKRRLSEKDCERGFILDGYPRTVAQAEFLDGFLKTQNKELTAAVLFEVPEEVVVQRLTARRICPKCGRIYNLISLPPKEDELCDDCKVKLVQREDDKEETVRHRYKVYLEKTQPVIDYYDKKGILKRVDGTIGIDNVIAEVLKIIGWSDK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNN2_HUMAN
Sequence: MVTSSFPISVAVFALITLQVGTQDSFIAAVYEHAVILPNKTETPVSQEDALNLMNENIDILETAIKQAAEQGARIIVTPEDALYGWKFTRETVFPYLEDIPDPQVNWIPCQDPHRFGHTPVQARLSCLAKDNSIYVLANLGDKKPCNSRDSTCPPNGYFQYNTNVVYNTEGKLVARYHKYHLYSEPQFNVPEKPELVTFNTAFGRFGIFTCFDIFFYDPGVTLVKDFHVDTILFPTAWMNVLPLLTAIEFHSAWAMGMGVNLLVANTHHVSLNMTGSGIYAPNGPKVYHYDMKTELGKLLLSEVDSHPLSSLAYPTAVNWNAYATTIKPFPVQKNTFRGFISRDGFNFTELFENAGNLTVCQKELCCHLSYRMLQKEENEVYVLGAFTGLHGRRRREYWQVCTLLKCKTTNLTTCGRPVETASTRFEMFSLSGTFGTEYVFPEVLLTEIHLSPGKFEVLKDGRLVNKNGSSGPILTVSLFGRWYTKDSLYSSCGTSNSAITYLLIFILLMIIALQNIVML
What is the function of this protein?
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine (PubMed:11491533).  Involved in the thymus homing of bone marrow cells.  May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.
What are the official names of this protein?
Pantetheine hydrolase VNN2, Glycosylphosphatidyl inositol-anchored protein GPI-80, Protein FOAP-4, Vascular non-inflammatory molecule 2, Vanin-2.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: KAD_MESH2
Sequence: MKSNKKILFIGAPGSGKGTISKILVEKYKLVHISTGDLFRKKISEDSRFAAQIQNYLSSGSYVPDEITNKLVADFIKKIPKNQGYILDGYPRTLQQLEFMIKNGINLDCVFYLKIKNETIISRLSQRLFCQKCQKSYNLLLAKPKNGLKCDLDNTDLITRNDDRPEIITHRIEKFNNSVIPIVEFFKKSGIIYYLDAEQTLEETVIEIEKWL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_GEOKA
Sequence: MNYDRILIRYGEMTTKGKNRNIFVRRLKNNIARKLQAFERIQIEYMRDRMYILLNGEPHEPIIEKLKTVFGIHSFSLAMKCENDLDAIKETALAAVRQLPYKGKTFKVSARRVDKQFPYRSDELNYEVGAHILRQTDGLRVNVREPDIDVRIEVRQDGTYVTCRDIFGAGGLPVGTSGKAMLMLSGGIDSPVAGYLAMKRGLEIEAVHFFSPPFTSERAKQKVIDLVRKLTTYGGRIKLHIVPFTEVQQAIYQGVPNEYSLISTRRAMLRITDALRRRQRALAIVTGESLGQVASQTLESMYVINEVTNTPILRPLVSMDKLEIIELAKQIGTHDISILPYEDCCTIFTPRAPKTKPKKEKVFHYESQLDLAPLLEKAVNDTETLVIDEETGQGDEFAELF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_THEYD
Sequence: MIKRRQTRRIYVGGVSIGDGAPVRVQSMTKTDTRNIKATIRQIKQLELAGCEIVRVAVPDITAAKVLGEIKKRIKIPMIADIHFNYKLALEAIKQGVDGLRINPGNIGAKWKVREVITAAKDRKIPIRIGVNAGSLPKDLIEKYGHPTHEAMVEAAERHIEILEELDFHDIKVSLKASDVMKTVEAYRLFSSKHDYPLHIGITETGPVPEGVVKSSIGIGLLLLEGIGDTIRVSLTDSPVVEVNVAYEILRVTGFREKGVEIISCPTCGRCEVNIKKMVKQVKNALRNVKEPIKVAVMGCSVNGPGEAKEADFGIAGGKGQGIVFVKGKILKTVKETELVNALIEEIRK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GNAO_BOVIN
Sequence: MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSPELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGSNTYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The G(o) protein function is not clear.  Stimulated by RGS14 (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein G(o) subunit alpha, GTP-binding protein G39.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Cell membrane. Membrane; Lipid-anchor.
Protein: ILVC_LISMC
Sequence: MTKVYYEDAVKNNALEGKTVAVIGYGSQGHAHSQNLRDNGNNVIIGIREGKSAESARNDGFDVYSVSEAAEKADVIMILLPDETQGETYENEIKPNLKAGNALVFAHGFNIHFDVINPPSDVDVFLVAPKGPGHLVRRTFVEGGAVPSLFAIYQDATGNARDTALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGATHLIQAGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMEKMRHSISNTAEYGDYVSGPRVVTADTKKAMKEVLTDIQNGNFAKSFIDDNKNGFKEFHRMRKEQQGHQIEKVGAELREMMPFVKPQH
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: XERC_ECOLU
Sequence: MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIL_RAT
Sequence: MEGVGAVRFWLVVCGCLAFPPRAESVCPERCDCQHPQHLLCTNRGLRAVPKTSSLPSPQDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEIGRLSRGSFEGLESLVKLRLDGNVLGALPDAVFAPLGNLLYLHLEANRIRFLGKNAFTQLGKLRFLNLSANELQPSLRHAATFVPLRSLSTLILSANSLQHLGPRVFQHLPRLGLLSLSGNQLTHLAPEAFWGLEALRELRLEGNRLNQLPLTLLEPLHSLEALDLSGNELSALHPATFGHQGRLRELSLRDNALSALSGDIFAASPALYRLDLDGNGWTCDCRLRGLKRWMGNWHSQGRLLTVFVQCRHPPALRGKYLDYLDDQLLQNGSCVDPSPSPTAGSRQWPISTAPGEGMTPPAGLAQELPLQPQPQPQQRGRLLPGVAWAGAAKELVGNRSALRLNRRGPGLQHQSPSAAAASGSAPQSLDLHEKPERGRPTRANLPQTEPTPTSEPASGTPSARDSWQRAAKQRLASEQQGRAVQYDSGVGLPPLVSDPCDFNKFILCNLTVEAVSANSASVRWAVREHRSPRPQGGARFRLLFDRFGQQPKFQRFVYLPERSDSATLHELRGDTPYLVCVEGVLGGRVCPVAPRDHCAGLVTLPEAGGRGGVDYQLLTLVLLAINALLVLLALAAWGSRWLRRKLRARRKGGAPVHVRHMYSTRRPLRSMGTGVSADFSGFQSHRPRTTVCALSEADLIEFPCDRFMDSSGGGTGGSLRREDHLLQRFAD
What is the function of this protein?
Component of the TLR4 signaling complex.  Mediates the innate immune response to bacterial lipopolysaccharide (LPS) leading to cytokine secretion and the inflammatory response (By similarity).
What are the official names of this protein?
TLR4 interactor with leucine rich repeats, Leucine-rich repeat-containing protein KIAA0644 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y890_VIBC1
Sequence: MGLFSKRQIGNQYETLAKQYLQRQGLRFLDQNFLTKVGEIDLIFQQGETIVFVEVKYRKNDSFGSAAEMVTRAKMRKLVKTAQIWLSQQKRSAYNIDYRFDVVAIHDSGRDINWIQNAISEG
What are the official names of this protein?
UPF0102 protein VIBHAR_00890.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: GUNF_ACET2
Sequence: MKKILAFLLTVALVAVVAIPQAVVSFAADFNYGEALQKAIMFYEFQRSGKLPENKRNNWRGDSALNDGADNGLDLTGGWYDAGDHVKFNLPMAYAVTMLAWSVYESRDAYVQSGQLPYILDNIKWATDYFIKCHPSPNVYYYQVGDGALDHSWWGPAEVMQMPRPSFKVDLTNPGSTVVAETAAAMAASSIVFKPTDPEYAATLLRHAKELFTFADTTRSDAGYRAAEGYYSSHSGFYDELTWASIWLYLATGDQSYLDKAESYEPHWERERGTTLISYSWAHCWDNKLYGSLLLLAKITGKSYYKQCIENHLDYWTVGFNGSRVQYTPKGLAYLDRWGSLRYATTQAFLASVYADWSGCDPAKAAVYKEFAKKQVDYALGSTGRSFVVGFGKNPPRNPHHRTAHSSWSALMTEPAECRHILVGALVGGPDGSDSYVDRLDDYQCNEVANDYNAGFVGALAKMYEKYGGEPIPNFVAFETPGEEFYVEAAVNAAGPGFVNIKASIINKSGWPARGSDKLSAKYFVDISEAVAKGITLDQITVQSTTNGGAKVSQLLPWDPDNHIYYVNIDFTGINIFPGGINEYKRDVYFTITAPYGEGNWDNTNDFSFQGLEQGFTSKKTEYIPLYDGNVRVWGKVPDGGSEPDPTPTITVGPTPSVTPTSVPGIMLGDVNFDGRINSTDYSRLKRYVIKSLEFTDPEEHQKFIAAADVDGNGRINSTDLYVLNRYILKLIEKFPAEQ
What is the function of this protein?
This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
What are the official names of this protein?
Endoglucanase F, EGF, Cellulase F, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
Protein: MURI_LISMH
Sequence: MKQAIGFIDSGVGGLTVVREVLKQLPHEQVYYLGDTARCPYGPRDKEEVAKFTWEMTNFLVDRGIKMLVIACNTATAAALYDIREKLDIPVIGVIQPGSRAALKATRNNKIGVLGTLGTVESMAYPTALKGLNRRVEVDSLACPKFVSVVESGEYKSAIAKKVVAESLLPLKSTKIDTVILGCTHYPLLKPIIENFMGDGVAVINSGEETASEVSALLDYHNLLDSTDEEIEHRFFTTGSTQIFKDIAKDWLNMPDMTVEHIKLGK
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: VATA_SULIL
Sequence: MNNGRIVRINGPLVVADNMKNAQMYEVVEVGEPRLIGEITRIEGDRAFIQVYEDTSGIKPNEPVYRTGAPLSIELGPGLIGKIFDGLQRPLDSIKELTKSPFIARGIKVPSVDRKTKWHFIPKVKKGDKIEGGDIIGIVNETPLVEHRILVPPYVHGTLKEIVAEGDYTVEDPIAVVDMNGDEVPIKLMQRWPVRIPRPFREKLEPTEPLLTGTRVLDTIFPIAKGGTAAIPGPFGSGKTVTLQSLAKWSAAKIVIYVGCGERGNEMTDELRQFPSLKDPWTGRPLLERTILVANTSNMPVAAREASIYVGITMAEYFRDQGYDTLLVADSTSRWAEALRDLGGRMEEMPAEEGFPSYLPSRLAEYYERAGRVKTVGKPERFGSVTVASAVSPPGGDFTEPVTSQTLRFVKVFWPLDVSLAQARHYPAINWLQGFSAYVDLVANWWNTNVDPKWREMRDMMVRTLIREDELRQIVRLVGPESLAEKDKLVLETARLIKEAFLKQNAYDDIDAFSSPQKQARVMRLIYLFNTHASRLVERGIPTKKIVDSMGQLLPEIIRSKAAIKNDELNKYDELERKLISVFENLEKEAGT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RL16_RICAH
Sequence: MLAPKKQKFRKAHKGRVASKAKAGTMLAFGSFGLKSIDGWRVTARQIEAGRKAATRCMKRQGRLWIRIFPDVPVSKKPAEVRMGKGKGSPEFFAVRVSPGKIMFEIEGVEENIALRALELASAKLPVRTRIVRRYE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ASIP_PANPA
Sequence: MDVTRLLLATLLVFLCFFTANSHLPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKKSKQIGRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRNSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: CPK1_CRYNJ
Sequence: MTIDQSQINFNVPSTYKLEEIVGEGAYGLVVAGTHLPSGTQVAIKRITPFDHTMFCQRTLREIKLLRHFHHENIISILDLIQPESYEVFNEVYLVQELMETDLHRVIRSQELSDDHCQYFVYQTLRGLKALHSADVLHRDLKPSNLLLNANCDLKICDFGLARSSAKPPPGTSDGGQGFMTEYVATRWYRAPEVMLSFQEYTKAIDLWSVGCILAEMINGKPLFPGRDYHHQLSLILQVLGTPTMDDFNEITSQRSKDYLRALEFTRRQDFSAICPKAKPAAVDLLKQTLTFSPSKRITVEEALMHSYVEAYHDPHDEPNAEPLKPGFFDFEFHQEKLSRDQWKRMIYDEVQDPVPTILSQWTESH
What is the function of this protein?
Responds to activation by environmental stress by phosphorylating downstream targets.
What are the official names of this protein?
Mitogen-activated protein kinase CPK1, Stress-activated protein kinase CPK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: VATE_DICT6
Sequence: MSLERIVERLETEKRTKIEEIKNKKEKEFQEFVAKKEKELEEWKEKQKRSLKEKLNREENTLAAQLKLKYNAEKLRIESDAIAKVKNLVLERLKSSSNEVYNKIWENLLERESIKSGEMILTKNEDKIDVDYFCKKYSLTLSKDRMEGNGGFVIQKDNLVIDLTVDTIIEELVNKNILEIAQILHGER
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: PGMC2_ARATH
Sequence: MVSFKVSLVSTSPIDGQKPGTSGLRKKVKVFKQPNYLENFVQATFNALTTEKVKGATLVVSGDGRYYSEQAIQIIVKMAAANGVRRVWVGQNSLLSTPAVSAIIRERVGADGSKATGAFILTASHNPGGPTEDFGIKYNMENGGPAPESITDKIYENTKTIKEYPIAEDLPRVDISTIGITSFEGPEGKFDVEVFDSADDYVKLMKSIFDFESIKKLLSYPKFTFCYDALHGVAGAYAHRIFVEELGAPESSLLNCVPKEDFGGGHPDPNLTYAKELVARMGLSKTDDAGGEPPEFGAAADGDADRNMILGKRFFVTPSDSVAIIAANAVGAIPYFSSGLKGVARSMPTSAALDVVAKNLGLKFFEVPTGWKFFGNLMDAGMCSVCGEESFGTGSDHIREKDGIWAVLAWLSILAHKNKETLDGNAKLVTVEDIVRQHWATYGRHYYTRYDYENVDATAAKELMGLLVKLQSSLPEVNKIIKGIHPEVANVASADEFEYKDPVDGSVSKHQGIRYLFEDGSRLVFRLSGTGSEGATIRLYIEQYEKDASKIGRDSQDALGPLVDVALKLSKMQEFTGRSSPTVIT
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Probable phosphoglucomutase, cytoplasmic 2, PGM 2, Glucose phosphomutase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MARK1_MOUSE
Sequence: MSARTPLPTVNERDTENHTSVDGYTETHIPPAKSSSRQNLPRCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYSEPELDLSDAKRIDIMVTMGFARDEINDALVSQKYDEVMATYILLGRKPPEFEGGESLSSGSLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWGKDTARRLGSTTVGSKSEVTASPLVGPDRKKSTASPSNNVYSGGSMARRNTYVCERSTDRYAALQNGRDSSLTEMSASSMSSAGSTVASAGPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGAAQRVPAASPSAHSISASTPDRTRFPRGSSSRSTFHGEQLRERRSAAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRRDPSEGEASGRADTARGSSGDPKERDKDEGKEAKPRSLRFTWSMKTTSSMDPNDMLREIRKVLDANTCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
What is the function of this protein?
Serine/threonine-protein kinase (By similarity).  Involved in cell polarity and microtubule dynamics regulation.  Phosphorylates DCX, MAP2 and MAP4.  Phosphorylates the microtubule-associated protein MAPT/TAU (By similarity).  Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly.  Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX.  Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
What are the official names of this protein?
Serine/threonine-protein kinase MARK1, ELKL motif serine/threonine-protein kinase 3, MAP/microtubule affinity-regulating kinase 1, PAR1 homolog c, Par-1c, mPar-1c.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Cytoplasm. Cell projection, dendrite. Note=Appears to localize to an intracellular network.
Protein: SLYX_PSEAB
Sequence: MELDARMDDLECRQAFQDDTLQALNDVVVEQQRSIERLQLQVAALIKRLEDVQGLVGEAGEDEAPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: ACD_METJA
Sequence: MWGRDYELKYISYPKSVAIIGASKTEGKVGYAIMKNLKDFNGKIYPINPKYDEIFGIKCYKSVLDVEDDIDLAVIVVPNIVVPKVLEECGKKGVKGAVIITAGFSEVGNYELENKIKEIAKRYNIRIIGPNCLGIMNTHINLNATFAKVFPPKGGVSIISQSGAVLNAILDIAPLLNIGFSKVVSIGNKADIQESDLLEYFLDDEDTKIVVLYIEGLKDKRFLKVAKKLSKKKPIIALKSGRTEVGKKAAKSHTGSLAGEDVIYEAAFKEAGIIRAYTFEELVDLIHLFSTQPTISSNEIGIITNAGGFGVLAADSCVDYNMKLSNFEKSTIEKLKNILPPTANISNPLDIIGDATPERYKKVIEVLAEDSNVKGLLVILTPQEMTKPLEVAKSIIEVKNSHKEFKNKPLITSFVGGVSVKGAKSYLRKNGIPAYITPENGVKALSHLYKYSLMKVKEDYDEYLENIKEEFIKITEENKEIIKELLSNPNEYTAKKLLSIYGLPVPKGYLAKNEDEALEYCKKLGKCVMKIVSPQIIHKTEAGGVIINPKNPKEAFKKLIENAKEYAKRMGIDNLIIEGVLVEEFIEKDMMEIIIGAKRDDIFGSVVMVGLGGVFVEVLKDVSFGISPITRDFAHEMLRELKSYKVLEGVRGRPKRDINFIVDTLIKIGVFMDIHKEIKELDLNPVFVFNEKEGGCIGDARIIK
What is the function of this protein?
Catalyzes the formation of acetate and ATP from acetyl-CoA by using ADP and phosphate.  Can also use butyryl-CoA, but not phenylacetyl-CoA.  Cannot catalyze the reverse reaction.
What are the official names of this protein?
Acetate--CoA ligase [ADP-forming], ADP-forming acetyl coenzyme A synthetase, ACS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the acetate CoA ligase beta subunit family.