PharMolix/UniProtQA huggingface dataset:
Protein: RS19_WOLTR
Sequence: MSRSAWKPPFCHPSVLRLVNRALKQGSINKVIKIHSRASVILPNCLGLKFAVYNGKDYIPVSVNDQNMIGHKFGEFSPTRKFAGHNGDKKAVRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SYA_CHRSD
Sequence: MKSADIRQAFLTFFEEHGHTIVPSSSLVPANDPTLLFTNAGMVPFKDVFLGRDPRPYVRATSAQRCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKRGAIRFAWTFLTERLGLPADKLWVTVHVSDDEAERIWKDEIGIDPARFSKLDEDNFWQMGDTGPCGPSSEIFFDHGPEVAGGPPGSPEEDGDRYIEIWNLVFMQFDRDSAGTLNPLPKPSIDTGMGLERVAAVLQGVHSNYEIDLFQNLLNAASEATGYDDTSAPSLRVIADHIRSCAFLITDDVLPSNEGRGYVLRRIIRRAIRHGHKLGAREPFFHTLVAALDAEMGAAYPELRKARPRIEKVLLKEEEQFARTLDHGMGLLTEALETLDGEVLPGETVFKLYDTYGFPFDLTADVCRERGVTLDEVGFQRELEAQRERARAASQFGADYTAALDLEGETAFTGYERLEDEARVTALVDREGNALAALEAGQHGVVVLDRTPFYGESGGQAGDTGYLEADGMRFQVTDTQKQGGHHLHHGVLVEGRLDVGASVTPRVDASLRAATMRNHSATHLLHEALRQVLGEHVQQKGSLVTAERLRFDVSHFEAMTRAQLDEVERIVNAQILANAATRIEHMTLDEAKAKGAAALFEAKYADSVRVLTIGADDFSIELCGGTHVARSGDIGCFHILSEAGVAAGVRRIEAVTGEGALAYFRDQEAKVARVAEQLKAKPEQVEARLEATLERNRTLEKELERLKAKLASATSGDMLADVREVAGVKLLAKQVEGVGGKELRGLLDQLKNKLGSGVIVLGVAGDEKVSLIAGVTDDLTARLKAGDLVKHVAEQVGGKGGGRADMAQAGGSRPQALPDALASVPSWVEARLGE
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_CAMJJ
Sequence: MRALALDVGLKRIGVALCVDKKIALPLDAVLRKNRNQAANEIKNLLKIHEISLLIVGIPKGGSREEEMTRRIKHFVSLLEFDKEICFVDESGTSKEALGYGVANTRKKDGKLDSLSAFIMIKDYFAL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_CERS1
Sequence: MSRPLTFLGIESSCDDTAAAVVRAEGTRAEILSSVVDGQTALHAAFGGVVPEIAARAHAERLDLCVERALEEAGLGLRDLDGIAVTAGPGLIGGVLSGVMLAKGLAAGTGLPLVGVNHLAGHALTPRLTDGLAFPYLMLLVSGGHCQFLIARGAEEFSRLGGSIDDAPGEAFDKTAKLLGLPQPGGPSVEAEAASGDPRRFAFPRPMLDRPGCDMSFSGLKTALLRARDGLVAEKGGLTRADRADLCAGFQAAVVDVLAEKTRRALAFYAAEGAARPALAVAGGVAANGPIRAALTSVAEAAGVRFLAPPLRLCTDNAAMIAWAGIERFRAGGRDGMELSARPRWPLDRSAPALIGSGRKGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_SHEB8
Sequence: MSKVLILKSSILGGYSQSAVLIDHLASHWETQGAAITVRDLGGKDVLPMVDGEIASGLRGGAELSVRQQEMLALSDTLVAELKANDTIVIAAPMYNFTIPAQLKNWIDFIARAGVTFTYTETGPKGLVEGKRAVLVTTRGGAHKDGPTDHVVPYLKTVLGFIGITNVEVVYAEALNMGPEAHDKGMSEAKHSIDQLKA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: IF2B_METS3
Sequence: MEEYENLLNRAIDQLPPEVFEHKRFKIPKAYSDIQGNRTFIKNFKDVAEDLNRDPQHVLKFLLRELGTAGNLEGSRAILQGKFTHYLINERLEDYVEKYVICHECNRPDTKIIREDRIFILKCAACGAKAPLKPL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: SRB8_CANGA
Sequence: MIPSKYKLAPPDDLHPYSESERAKHKIYPDFDPWKHTKEEDEILLNFVSKGYYSTSKVNFESISARSSLQDSLPKLSSTLSEKFSEVVRIREREINTIKGNSKDGMAASKFTDLCGPDFKLPSRLTLTDHRKELWLQELSSPYTPLHKITSFIPHGLKRRQVLEQCYIKQIPLKRAVWLIKCCYSIEWKTGIAKYANSPQEKDKFNAHLLKEWTDNFVHILEKLIFEMTQHYNDSVKLEAWKTEVSYFLKLVGNCYTLELIDKNTFHFWILQFVSKVENFEYLPLPLHILELFWSGICNTNSTKVNESESNPLYMVTKLTDILLNQYYIILHSKSMINDDKYIINDIKKNNSIKESLLASIQKLICILFKQQSLEVFLFPPTSWEKYKPCLIQITSALYRKSDEVAEIKRKLELISYRNETLKYTPPISENKVKDDLILTTFTENSGSITVVELSQVDTGLTGALDDNATDFDWTSYSDQEISTKIQIIQIILWAIHPSRHSHYEAGQLAAKLLLLKINTMDGFPEYEIEDEIWSLVFKLAKLSDKSKALPAVLEALYSLLNTLIVYGLIKVSTYIRKLISSGILYLTESNDKYIHCRLLINLKMSPLMKSQYNMVLKNVMDQDPEYYNNYNFDQIVSIVEDLKVKLPNGDAIEYSNYPMSVKISLGEWYLTYLCNGKLVNETRESLTEKYVLFAHQLNTNHLYFKWIEFIVYHQLIEDIETLEYLMEVLLRYKKLFSQYINDHVLFIKTFIFIIRRILKERDSIAYSLTSFMDFWKFIMKSYSLEIRADTDLRSEMSAVYEEEKAKKEITEGEKDSWMGLYQNIHPDSTSLDQNHTGFSELFLTNLKTFLSSKQDKQAKKKARYNLLLLMQAKNRDYSKFISIYLKRKDFKTSDLVNLLSSKLLTLDQIKNTYGLKYVLELFDIESESNCVFYEYQKRCYIELNYKSVLSEYNVVSHHEMNRFIFKIVNHSTSAKLKETASALLTKNLEANKDKAIQLFYQLVYYQNNLEFLSSEELQEFAVNNSPQKLYSYLDFTNLWLFQSFTKFYIHETFQNTNEDKVKVGDVIFSIIETTKYNVLCAKIFEDIRDHRVTDLVIELFEQDFFKKIISGEEFKAEFLQMLIEIINHLSMHKGKTNDRSGEQSHTSYELCVQVMAHFQQLSDSELSAKEIELDVFMKIFTVHQNSVFQEILRDTESSSAMIESLFALFERVNFSLRLKLMFYEVLSSLKSYCTYEAGISDEQSRTKLMHKLMCLPPFQVSSFFPEEDDTDCTRDPALSLGLDLGTASANSTSSTTPSEGTHKKRCAIWDKRLHKYTGELQRKPYYCIKNYQDTEDINNCSLNLSLFDARYERNNPR
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROD_LATSS
Sequence: MHLEFTTGQTQTAVSLMPRHLDDCLRELILINQKKDAIDILEWRLDYWQAPAQLLTAAEKIAALDLPLILTVRTTNDGGLASAQDYLTYYAPLIKAHIGQAIDLEWSLAAEQRHQLAELAHQQHYQVLLSHHDTVQTPDNDTLRTQLLAMQADPDADLLKLATTAQSPADTTRLLAATQSFTHQFDKPLTTMAMSEFGVASRIFGGQFGSAISFGYLETPSAPGQLPIEQLKGLLTTNQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: LDH2_BACHK
Sequence: MKKGINRVVLVGTGAVGCSYAYSMINQGVAEEFVLVDVNEAKAEGEAMDLSHAVPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGIFLIATNPVDILTYVTWKESGLPKERVIGSGTTLDSARFRYMLGDYLDVDPRNVHAYIVGEHGDTELPVWSHATIGVQKLETILANNEQYKQEDLDKIFENVRDAAYHIIERKGATYYGIGMSLLRVTKAILNNENSVLTVSAYLEGQYGEKDAYVGVPAVINREGVREIVELELNEEEKAKFAHSVKVLKETMAPVL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_I80A6
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWATNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: SFI1_SCHPO
Sequence: MSKNGAPKYVDGGRKIMDEDLRRDLEILRLILLRLSHAADDTSPLDVFNAYESVLRENGLNPARHRSYIRILYRLISSKKLSWNDEWRNLMRRIGFSQVSSDLNTPLFPLNNTDMENDPFIVNGDDYRSRSNQQKSSQFASEVAQTIKSQTAMFRRADQYRSQKDKILLANSLDFMLEKYRYYKKIDAVYLRKADAVYRAFIMLKYFPRWVQKLRNIQSRIYSAGEAYRLILIGQMVNRWRQKTRERLHQKLRFQKNAFLLDVLLKWSALTVNWNRKHEYMLKRRVFTNWMSKRRRNESLIQKANVFFQHSVLAHSFKTWKANLSIKNAATLYEKKVVFMSFNRWHANYESHVLDLQKAELFSQKAYYSIALHKWKLRIEELSDLMNKADDLYEVNLLQRMLVLWRRKATTYEKIDFWMDGHDVDIVKSAFFKWKNKFIKVDRNFELADTILQNTFLTKWRLAVRVKVVQEKRNKDRLIVTFRFWYYLMKAKSFQHKRDHRLLTIAWEAWKDNYQRRIKLQKEAQELQLTRIQKIAKQYLIKWRISLLDIKELSIRAEKLHTTNEIIGVWNQWVVSYNRKVGMQQNADLFFKRKTLRVVFEHWRYLRETNMLLRLENKVVDFREVQSEKLVLRCWNAWVARLLSVSQMLDTAELSTQKVVVRAYEAWSFRYNHQKEIMSQADQFYNERLMRSAMVFWRYQLRAIKFYFNISDWKRREFNRQTLRNAFDAWHLLMFRVTSLVMQADRFHEQKKNKLLGKYFRKWLQRMQLNQEESSLLEAEATIEGNRTSRYMHTFDTTLPMQNDEFTDESVNFENRWKQELKTPISRFSKFLRPIPPNTR
What is the function of this protein?
Component of the spindle pole body (SPB) half-bridge involved in the initial steps of SPB duplication.
What are the official names of this protein?
Protein sfi1, Suppressor of fermentation induced loss of stress resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the SFI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Spindle pole, half bridge.
Protein: SYR_STAAR
Sequence: MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_HELPH
Sequence: MIDRKLLLQDFDKVALSLKKRNHAMGDELERLREVITHYKKQLIELEGLQAFQNKVSKEFGIKMAQKVDTSDLKKELENNKIKLNELSKSVGELEQQIDLKLSIIPNLVDEKTPLGASEEDNIEIKKILTPRVFTFKPKEHFELAQQNGWIDFESGVKLAKSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLYNDTIIGVENLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHSKESDAMQEHMLESASEILKALELPHRFVQLCSADLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQEDGSIHIPKALEKYL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAX1A_ORYSJ
Sequence: MEAAAAMEAGRKLAARHPHGRSRTAHNMSSSSLRKKSDAALVRKVPVAPLRPLLANLQEVFLATKLAVLFPAVPLAIAAQCFRFDQVWVFALSLLGLIPLAERVSFLTEQIALYTGPTVGGLLNATCGNATELIIALFALLKGKIEVVKCSLLGSVLSNLLLVLGTSLFCGGVVNLGARQPYDRNQSDVSTALLFLAVLCHSAPLLLRYAVAAGEHSVSATSAAASLDLSRACSFVMLASYVAYLFFQLKTHRQLFEPQEVDGGDAGDDDEEPALGFASALFWLALMTAVISVLSEYVVGTIEPTSQSWGLSVSFISIILLPIVGNAAEHAGAIIFALKNKLDITLGVALGSATQISMFVVPLSVLVAWIMGVQMDLDFKLLETGSLFMAVLVTAFTLQDGTSHYLKGILLLLCYIVIGACFFVARQPAGHANSNGALLDVPTGSMSVQAA
What is the function of this protein?
Vacuolar cation/proton exchanger (CAX).  Translocates Ca(2+) and other metal ions into vacuoles using the proton gradient formed by H(+)-ATPase and H(+)-pyrophosphatase.
What are the official names of this protein?
Vacuolar cation/proton exchanger 1a, Ca(2+)/H(+) exchanger 1a, OsCAX1a.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: COBS_AGRVS
Sequence: MTLTAFVDDLARSLGFLSRLPIASRFFQNHSGEMSRTPRAFPLAGAVITAPAGLLLALMLGLGASSMVAAFAAIGLQVLLTGALHEDGFADTADGLGGANRERALDIMKDSRVGTFGVLALVFGVGLRVAALASLVNSLSPINVALVMIGIAAVSRALMVWHWHALPPAKPDGVAASLGKPEDNTLYTALFLGLAVAVVTIAPVTSFHPLAVMLVASGAAAFASNRLVSHRLGGQTGDTIGATQQICEITALASIAMAL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RHAM_MANSM
Sequence: MIRKGFVMQVNPDCHAEYKKRHDEIFPELVEELKSHGAHHYSIFLDKQRNLLFGYVEIENEQRWNDVAKTAACRKWWAFMRDVMPSNPDNSPVSQELEQVFYLD
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_PSEA8
Sequence: MALAKRIIPCLDVDNGRVVKGVKFENIRDAGDPVEIARRYDEQGADEITFLDITASVDGRDTTLHTVERMASQVFIPLTVGGGVRSVQDIRNLLNAGADKVSINTAAVFNPEFVGEAADRFGSQCIVVAIDAKKVSAPGEAPRWEIFTHGGRKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGVKSGYDLGVTRAISEAVNVPVIASGGVGNLEHLAAGILEGKADAVLAASIFHFGEYTVPEAKAYLASRGIVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXPB5_ARATH
Sequence: MASSSLKCFSFIVVLTTFFAISLKPCYCHNKTHWNTAGITWYGDREGPGTTGGACGYGDAVAKHPYRCMVSAGGPSLFKDGKGCGACYRLKCDHPLCTKKPIKVMISDECPGCTKESVHFDLSGKAFGALAKRGKGDQLRNLGELKVSYKRACCKHPKTMIAIHVDAGANPYYMSFAVKFANGDGNFACIEVQPAGGQYMKMEEMRSAVWRLSPGVPLKGPFNIRLTSAVSGKKIIAKGVIPEKWSPGAIYHSKVNFPVQRKQK
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-B5, At-EXPB5, AtEXPB5, Ath-ExpBeta-1.3, Beta-expansin-5.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: MLE_ARGIR
Sequence: MPKLSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRNEDVFAVGGTHKMGEKSLPFEEFLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERLSDEDVDEIIKLTDLQEDLEGNVKYEDFVKKVMAGPYPDK
What is the function of this protein?
In molluscan muscle, calcium regulation is associated with myosin rather than with actin.  Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.
What are the official names of this protein?
Myosin essential light chain, striated adductor muscle, E-LC, Sulfhydryl light chain, SHLC.
Protein: SL9A5_RAT
Sequence: MLRVALLLLPGLPLAGVGATEEPTQEPGPLGEPPGLALFRWQWHEVEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLALGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGVALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTAVKYTMKTLASSAETVIFMLLGISAVDSSKWAWDSGLVLGTLFFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLRVKRSDYHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQGGHVLSSAGLTLPSMPSRNSVAETSVTNLLRESGSGACLDLQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLESFKSTKHNICFTKSKPRPRKTGHKKKDGVANPEATNGKPPRDLGFQDTAAVILTVESEEEEESESSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPRIIPPSPTCAEKELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLESLASPPCTQPPTLTRLPPHPLVPEEPQVPLDLSSDPRSSFAFPPSLAKAGRSRSESSADIPQQQELQPLMGHKDHTHLSPGPANSHWCIQFNRGGRL
What is the function of this protein?
Plasma membrane Na(+)/H(+) antiporter.  Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry.  Responsible for regulating intracellular pH homeostasis, in particular in neural tissues (PubMed:9933642).  Acts as a negative regulator of dendritic spine growth.  Plays a role in postsynaptic remodeling and signaling.  Can also contribute to organellar pH regulation, with consequences for receptor tyrosine kinase trafficking (By similarity).
What are the official names of this protein?
Sodium/hydrogen exchanger 5, Na(+)/H(+) exchanger 5, NHE-5, Solute carrier family 9 member 5.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FRSA_SALG2
Sequence: MTQANLSETLFKPRFKHTETSTLVRRFNRGSQPPMQSALDGKNVPHWYRMINRLMWIWRGVDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWAKQAMDWQQKACQEQDAMRSGRYWLHASTLYNIAAYPHLKGDELAEQAQALANRAYEEAAQRLPGSLREMEFAVPGGSPVTAFLHMPKGDGPFPTVLMCGGLDAMQTDYYTLYERYFAPRGIAMLTLDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLEAPRLKAVACLGPVVHALLSDPQRQSTVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGFWKNDPFSPEEESRLITTSSSDGKLIEIPFNPVYRNFDHALQEITDWINHRLC
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: 194K_TRVSY
Sequence: MANGNFKLSQLLNVDEMSAEQRSHFFDLMLTKPDCEIGQMMQRVVVDKVDDMIRERKTKDPVIVHEVLSQKEQNKLMEIYPEFNIVFKDDKNMVHGFAAAERKLQALLLLDRVPALQEVDDIGGQWSFWVTRGEKRIHSCCPNLDIRDDQREISRQIFLTAIGDQARSGKRQMSENELWMYDQFRKNIAAPNAVRCNNTYQGCTCRGFSDGKKKGAQYAIALHSLYDFKLKDLMATMVEKKTKVVHAAMLFAPESMLVDEGPLPSVDGYYMKKNGKIYFGFEKDPSFSYIHDWEEYKKYLLGKPVSYQGNVFYFEPWQVRGDTMLFSIYRIAGVPRRSLSSQEYYRRIYISRWENMVVVPIFDLVESTRELVKKDLFVEKQFMDKCLDYIARLSDQQLTISNVKSYLSSNNWVLFINGAAVKNKQSVDSRDLQLLAQTLLVKEQVARPVMRELREAILTETKPITSLTDVLGLISRKLWKQFANKIAVGGFVGMVGTLIGFYPKKVLTWAKDTPNGPELCYENSHKTKVIVFLSVVYAIGGITLMRRDIRDGLVKKLCDMFDIKRGAHVLDVENPCRYYEINDFFSSLYSASESGETVLPDLSEVKAKSDKLLQQKKEIADEFLSAKFSNYSGSSVRTSPPSVVGSSRSGLGLLLEDSNVLTQARVGVSRKVDDEEIMEQFLSGLIDTEAEIDEVVSAFSAECERGETSGTKVLCKPLTPPGFENVLPAVKPLVSKGKTVKRVDYFQVMGGERLPKRPVVSGDNSVDARREFLYYLDAERVAQNDEIMSLYRDYSRGVIRTGGQNYPHGLGVWDVEMKNWCIRPVVTEHAYVFQPDKRMDDWSGYLEVAVWERGMLVNDFAVERMSDYVIVCDQTYLCNNRLILDNLSALDLGPVNCSFELVDGVPGCGKSTMIVNSANPCVDVVLSTGRAATDDLIERFASKGFPCKLKRRVKTVDSFLMHCVDGSLTGDVLHFDEALMAHAGMVYFCAQIAGAKRCICQGDQNQISFKPRVSQVDLRFSSLVGKFDIVTEKRETYRSPADVAAVLNKYYTGDVRTHNATANSMTVRKIVSKEQVSLKPGAQYITFLQSEKKELVNLLALRKVAAKVSTVHESQGETFKDVVLVRTKPTDDSIARGREYLIVALSRHTQSLVYETVKEDDVSKEIRESAALTKAALARFFVTETVLXRFRSRFDVFRHHEGPCAVPDSGTITDLEMWYDALFPGNSLRDSSLDGYLVATTDCNLRLDNVTIKSGNWKDKFAEKETFLKPVIRTAMPDKRKTTQLESLLALQKRNQAAPDLQENVHATVLIEETMKKLKSVVYDVGKIRADPIVNRAQMERWWRNQSTAVQAKVVADVRELHEIDYSSYMYMIKSDVKPKTDLTPQFEYSALQTVVYHEKLINSLFGPIFKEINERKLDAMQPHFVFNTRMTSSDLNDRVKFLNTEAAYDFVEIDMSKFDKSANRFHLQLQLEIYRLFGLDEWAAFLWEVSHTQTTVRDIQNGMMAHIWYQQKSGDADTYNANSDRTLCALLSELPLEKAVMVTYGGDDSLIAFPRGTQFVDPCPKLATKWNFECKIFKYDVPMFCGKFLLKTSSCYEFVPDPVKVLTKLGKKSIKDVQHLAEIYISLNDSNRALGNYMVVSKLSESVSDRYLYKGDSVHALCALWKHIKSFTALCTLFRDENDKELNPAKVDWKKAQRAVSNFYDW
What is the function of this protein?
Is a methyltransferase active in RNA capping and an RNA helicase.  Methyltransferase displays a cytoplasmic capping enzyme activity.  This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus.  Helicase region probably exhibits NTPase and RNA unwinding activities (Potential).
What are the official names of this protein?
Replicase large subunit, 194 kDa protein, RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: HEM1_THEVO
Sequence: MLMNIVTLISWDFKRNNESFQRAIINGYDYWSRILDDHGVEKYVILLTCNRVELYYRGDPFDVQEKGYNIISDDMAINHLFHVAAGLDSMSIGENEVLKQVKQAYEKSSSMGKSDKFLSLIFQRAISVGKLVRSKTGIGKGKVSIPSIVYDIVRKNGGNKILLVGNGMLASEIAPYFSYPQYKVTVAGRNIDHVRAFAEKYEYEYVLINDIDSLIKNNDVIITATSSKTPIVEERSLMPGKLFIDLGNPPNIERGNNVITLDEIYEISKKNEMLREEKINQAEILIENEMKATMNKIKDLMIDDIFSQFYRFASVVQTMEIQKFRKMHPEVNENDLEALAHSIINKILNVPVTTLKAVSRSQGNSDFNRLFESFSSNFNDIVSAALQSYEGLRDTQSLRDRTRQLLQKS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.