PharMolix/UniProtQA huggingface dataset:
Protein: RL29_YERE8
Sequence: MKAQELREKSVEELNTELLNLLREQFNLRMQAASGQLQQTHLSKQVRRNIARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ERA_DESVV
Sequence: MNQTTHRCGWVALIGPPNAGKSTLLNALIGQKVAIVTSKPQTTRNQIVGILSRKDAQVVFMDTPGIHQLRGRLNKMLLQTAWQSMNAADALIVMLDGDLYIRKPDLLDRDIAPLVEPIAAETRPVVVVVNKIDLFRDKSKMLPLLERLSAMWPKAEVFPASALNKDGMDHLLRLIVGYMPEGPALYPEDQISTLPVRFMTAEIVREKVFNKLRQELPYSTAVDIEQWEEEEGRDQVIVNAVIYVARPSHKSMVIGKGGATIKEIGIEARKDIQELLEKRVHLELWVKVREGWTEDLGFMRSLGLSPDE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: FLGN_YEREN
Sequence: MVVERLQTNLGQQLELLESLKTVVAQEQQLLCSGRIQGIVLQGVTEQKSSILATLAYLDQTRLTTEKNINIQAPYSNVPALAERWQRILELAEGLRYSNLHNGLLLQQHIEHNTQALAVLNTRHGQSLYGPDGHAKGASLLGRKIGI
What is the function of this protein?
Required for the efficient initiation of filament assembly.
What are the official names of this protein?
Flagella synthesis protein FlgN.
What is the protein family that this protein belongs to?
Belongs to the FlgN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_ECOHS
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGATGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: THIM_SALCH
Sequence: MQPDLHCRTLAAHTLKHFRALSPLTHCMTNDVVQTFTANTLLALGASPAMVIDPVEARPFAAIANALLVNVGTLTASRADAMRAAVESAYDAKTPWTLDPVAVGALEFRRRFCLDLLSLRPAAIRGNASEILALSGMALGGRGVDTTEAALAALPAAQALAHQIDCIVVVTGEIDYVTNGQRTLSIPGGDPLMTRIVGTGCALSAVVAASCALPGAALDNVASACCWMKLAGQAAAERSEGPGSFIPAFLDALYHLDVEAANEEN
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: DIVIB_LIMRS
Sequence: MLDDRSAIEHHKYSQRLTELERRSAAAQQRQQKKKPPKMHVGNKIRGIKIKRYVSNGERVLKLVVLFSAILLFMLYIISPLSKITTLHVTGNHDLTKEQVEKNANIYPGRFIWGVYLARHQLTKQAIRKNPQIKDLRIKVTGPQSLQISVKENALLGIAVMNNDTYAVLADGQLQRTKNADNGIAYKRFDGHKKVLATTAAQLGKLKLAIRNGISSVSYQPTKEYPDRVIIYMRDGNTVYGDLNTIGDKMGYYPAIAASMKNKGIIDLQVGAYSYDYGSKDK
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: 5DNU_ECO55
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T1SX_MYCPN
Sequence: MTPKLKLNTNSNWTKKTLGSLFELKKGEMLEKELLAPDGKYEYFNGGIKASGRTNEFNTFKNTISIIIGGSCGYVRLADKDYFCGQSSCTLTVLDPLEIDLKFAYYALKSQEEKITSLASGTTIKNIRLSDLKDLPIPLVKSIQDQRTIAHALSVFDLRIEHLNELIEVNRKLRDEYAHKLFTLDPDFLTHWNLHELHEQMGEISLGEVFHLKSGKYLKADERFEDGKFPYYGAGIESTSFVNEPNTKGDTLSMIANGYSIGNIRYHTIPWFNGTGGIAMEALKPNKTYVPFFYCALKYMQKDLKERFKRDESPFISLKLAGEIKVPFVKSFALQRKAGKIIYLLDKTLEECKEEAKSLISIRDNLLGKLFPTLS
What is the function of this protein?
The specificity (S) subunit of a type I methyltransferase (MTase); this subunit dictates DNA sequence specificity.  The single R subunit has multiple frameshifts and is probably not expressed.
What are the official names of this protein?
Putative type I specificity subunit S.MpnORF638P, S protein, S.MpnORF638P.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: NDBW1_LYCMC
Sequence: MKCKKQLLVIFFAYFLVVNESEAIFGSLFSLGSKLLPSVFKLFSRKKQRALMKRDLEDIMDPYQKNLKLDRYLRRLAMD
What is the function of this protein?
Broad spectrum of activity against both Gram-positive and Gram-negative bacteria and S. cerevisiae.  Has insecticidal and hemolytic activities.
What are the official names of this protein?
Ponericin-W-like 32.1.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Medium-length antimicrobial peptide (group 3) family. Ponericin-W subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: METK_CLOPS
Sequence: MRRLFTSESVTEGHPDKICDQISDAVLDAIFAKDPNARVACETAVTTGLVMVMGEITTNCYVDIPKIARETIKNIGYDRAKYGFDCETCSVMTTIDEQSSDIAMGVDEALESRAGEKIDIDAVGAGDQGMMFGFATNETEEFMPAPIAMAHRLSRRLTEVRKNGTLPYLRPDGKTQVTVEYENDKPVRIDAIVISTQHGPEVSQEQIQADLMEHVIKAVIPAELLDENTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYGRHGGGAFSGKDPTKVDRSAAYAARWVAKNLVAAGIADKLEVQVAYAIGVAKPVSIIVDTFGTGKISDEEIVNIINKVFDLRPGAIIRDLDLRRPIYRQTAAYGHFGRTDLDLPWENLNKVEEIKKYL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAC1_TRAMX
Sequence: AVGPVADNTITDAATSPDGFSRQAVVVNGVTPGPLVAGNIGDRFQLNVIDNLTNHTMLKTTSVHWHGFFQQGTNWADGPAFINQCPISPGHSFLYDFQVPNQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPHASRYDVDNDDTVITLADWYHTAAKLGPRFPAGADATLINGKGRAPSDTSAELSVIKVTKGKRYRFRLVSLSCDPNFTFSIDGHNLTIIEVDSSNSQPLSVDSIQIFAAQRYSFVLNANQAVDNYWIRANPNFGNVGFNGGINSAILRYDGAPAVEPTTNQTTSVKPLNEVNLHPLVSTPVPGSPSSGGVDKAINMAFNFNGSNFFINGASFVPPSVPVLLQILSGAQTAQDLLPSGSVYVLPSNASIEISFPATAAAPGAPHPFHLHGHTFAVVRSAGSTVYNYSNPIFRDVVSTGTPAAGDNVTIRFLTNNPGPWFLHCHIDFHLEGGFAVVQAEDVPDVKATNPVPQAWSDLCPTYDANAPSDQ
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase, Benzenediol:oxygen oxidoreductase, Diphenol oxidase, Urishiol oxidase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: Y049_SIFVH
Sequence: MVRALLFHVITYTKFIVPVVKLLIMSAIAGVIAGAFGGGIGGVGDAIGTIIGDLERAIARFGGSIVNAFKTVIDKILTLAVRIGRIIEKYFRIAVHYIVLFLRLAYRYMYSFYTEFQKDPWRSLQFVGSMAILLNNSLFP
What are the official names of this protein?
Putative transmembrane protein 49.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: LIGA_TRAVE
Sequence: VTXPDGKNTATNA
What is the function of this protein?
Depolymerization of lignin.  Catalyzes the C(alpha)-C(beta) cleavage of the propyl side chains of lignin.
What are the official names of this protein?
Ligninase A, Diarylpropane peroxidase, Lignin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Ligninase subfamily.
Protein: LKTA_BIBTR
Sequence: MGTKLTLSTLSNGIRSTLTATRGGLNRAGQSLTQAGQTLKNGAKKIILYIPKDYKYDSGSGNGLQDLVKAAEELGIEVQKEEGNDIAKAQTSLGTIQNVLGLTERGIVLSAPQLDKLLQKNKVGQALGSSESIAQNFSQAKTVLSGVQSILGSVLAGMDLDEALQNESDQLTLAKAGLELTNSLIENIANSVQTLDAFSEQISQFGSKLQNVKGLGALGDKLKNIGGLDKAGLGLDVISGLLSGATAALVLADKDASTAKKVGAGFELANQVVGNITKAVSSYILAQRVAAGLSSTGPVAALIASTVALAISPLSFAGIADKFDRAKSLENYAERFKKLGYEGDSLLAEYQHGTGTIDASVTAINTALAAIAGGVSAAAAGSVVASPIALLVSGITGVISTILQYSKQAMFEHVANKIHNKIVEWEKNNGGKNYFENGYDARYLANLQDNMKFLLNLNKELQAERVIAITQQQWDSNIGDLAGISRLGEKVLSGKAYVDAFEEGQHLKADKLVQLDSAKGIIDVSNTGEAKTQHILFRTPLLTPGTEKRERVQTGKYEYITKLHINRVDSWQIKDGAASSTFDLTNVVQRIGVELDHAENVIKTKETKIVATLGDGDDNVFVGSGTTEIDGGEGYDRVHYSRGNYGALTIDATKETEQGSYTVNRFVESGKALHEVTSTHTALVGNREEKIEYRHSNNQHHAGYYTKDTLKAVEEIIGTSHNDIFKGSKFNDAFNGGDGVDTIDGNDGNDRLFGGKGDDIIDGGNGDDFIDGGKGNDLLHGGKGDDIFVHRQGDGNDSITESEGNDKLSFSDSNLKDLTFEKVNHHLVITNTKQEKVTIQNWFREAEFAKTIRNYVATRDDKIEEIIGQNGERITSKQVDELIEKGKGKIDKSDLSQVVDNYQLLKYSRDASNSLDKLISSASAFTSSNDSRNVLASPTSMLDPSLSSIQFARAA
What is the function of this protein?
Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture.  The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca(2+) and lysis of the host cell (By similarity).  This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis.  It has also weak hemolytic activity.
What are the official names of this protein?
Leukotoxin, Lkt.
What is the protein family that this protein belongs to?
Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein.
Protein: NDK_HELAH
Sequence: MKQRTLSIIKPDALKKKVVGKIIDRFESNGLEVIAMKRLHLSVKDAENFYAIHRERPFFKDLIEFMVSGPVVVMVLEGKDAVAKNRDLMGATDPKLAQKGTIRADFAESIDANAVHGSDSLENAHNEIAFFFATREF
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_DROYA
Sequence: MGILGLSKLIADLAPQAIRESEIKNFFGRKVAIDASMCLYQFLIAVRSEGAQLATVNGDPTSHLMGMFYRTIRLLDNGIKPVYVFDGKPPDLKSGELAKRAERREEAEKALKAATDAGDDAGIEKFNRRLVRVTKEHANEAKELLTLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTFGSTKLLRYLTYSEARKMPVKEFSYEKLLEGLSINSREFIDLCILLGCDYCESIKGIGPKRAIELINNYRDIETILDNLDSSKYTVPENWNYKVARELFIEPEVANADNIDLKWVEPDEEGLVKFLCGDRQFSEERVRNGAKKLMKSKQAQTQVRLDSFFKTLPSTPNATNAAKRKAEEAKKSANNKKAKTSGGGGGRGRRPK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: PB2_I45A0
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMIPERNDQGQTLWSKMNDAGSDRVMVSPLAVTWWNRNGPMTSTIHYPKIYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELKDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDIDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEMSMRGVRVSKMGVDEYSSAERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKVTKRLTVLGKDAGTLTEDPDEGTAGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: ISPE_SHEB8
Sequence: MPAAISRNWPAPAKLNLFLHINGRRADGYHELQTLFQFIDCCDMLDFKVTETPELILHSNMSGVVADSDNLILRAAKSLQQTTGFNGGAEIWLDKRLPMGGGLGGGSSDAATTLVALNKLWHTQLSTEELAKIGLKLGADIPVFIHGFAAFAEGVGERLQAVNPGEPWYLVIAPDAHVSTADVFQDPLLPRDTPKLAIDTLMSQPWANDCQKLVVSKYPQVAKALGWLLEYAPSRMTGTGACVFGEFTQQQQALAALAKLPSEMQGFVAQGMNLSPLITRLSHP
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: YFKA_BACSU
Sequence: MTQNTKLRPITPEFDPWEAYMDVDQYGDMQLTNVEFTTTTLCNMRCEHCAVGYTLQPKDPNALPIDLLLKRLEEIPRLRSISITGGEPMLSLKSVKEYVVPLLKYAHERGVRTQINSNLTLDIERYEWIIPYLDVLHISHNWGTVEDFAEIGFAMMDRKPTFEQRARYFEKMIENSRTLVDAGVMVSAETMLNKRTLPHIEHIHRQITEDMKCQRHEVHPMYPSDFASALESLSLKEMRQAIHRLLDIRDENTWMLFGTLPFYACSPDEDDQKLLRRLRAAKNVTVRNDPDGRSRLNVNIFDGNIIVTDFGDTPPLGNIQTDSLPSAYEKWRETKLAKELSCHCPNVRCLGPNVLVKNSYYQDTDFTKRQARS
What are the official names of this protein?
Putative protein YfkA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily.
Protein: YL697_MIMIV
Sequence: MDQMELFDDYLLYCVGCCNKGEIESRLSKPKGVCRMKLDKGKKITVEYVPEDNYIYIDLENAIQFIKFISKHNYFCYEIDGDYHKCKMDKYIHRYIMFVITNNMEDHIEIIFSRLLPAYKNFKGTHTTDFIKLLISGITKYNSEQLVKTIIDNYPYNDYSLLFEKVIEGNADKDLIEYTIDAYRKKLFRYIKKNKNILPKVDLEDILFQFIITNDVDMFNFVVNSFMDISNDFQELKINDKQQKKIDDLTKLFDYEKFSHSLISAAIENNSYKIISQLIDDSVGLDYFDYRSLRYIMKEEKFEVFDVVLEKVIKHDKKMINRLFLKSYHYEIPIIDSLISYGANYNKYGHTVIFLAKLNDYTEVVEFLKKIINGQ
What are the official names of this protein?
Uncharacterized protein L697.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L17x/L18x family.
Protein: SEL10_CAEBR
Sequence: MWPRNDVQMDEGSMTPEDQEPEPAIDQDMEFDVNLEENSYSNGSGSSYNADKLSSSSPLQHKLDLSASPTQNNEANPRVEHLVALFKDLTVAEQMEAFARLVQESNMSNIRQMRAIIEPHFQKDFLSCLPVEIGIKILQNLNSTDLMKVAQVSKNWKMLSEVEKVWKSLEDRGFKNLLEPSDRTRGAWEATAVIPGVNIPDHVNQCEINIHRLVKLLKYGPIYERSADKSRYLRGEKIEKNWHSRPIMGSAILRGHEEHVITCMQIHNDLLVTGSDDNTLKVWSIDDGEVKHTLNGHSGGVWTSQISQCGRYIVSGSTDRTVKVWRAEDGFLLHTLQGHTSTVRCMAMANTTLVTGSRDCTLRVWDIETGLHVRTLQGHQAAVRCVQFDGNIVVSGGYDFTVKIWDAFSGKCLRTLIGHSNRVYSLLYESERSIVCSGSLDTSIRVWDFSRPEGQELIAFLSGHTSLTSGMQLRGNILVSCNADSHVRVWDIYEGTCIHILSGHRSAITSLQWFGRGLVATSSDDGSVKLWDIERGVLIRDLVSLNSGGNGGCIWRLCSTQTMLACAIGSRNNTEETKVILLDFDANHP
What is the function of this protein?
Probable substrate recognition component of SCF (SKP1-CUL-F-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Regulates synapse elimination in early development in the motor neuron HSNL.  Cell autonomous negative regulator of lin-12/Notch-mediated signaling, with respect to lin-12 activity in cell fate decisions and tumorigenesis.  May target the intracellular domains of lin-12/Notch proteins for ubiquitin-dependent degradation.  Involved in sex determination by promoting female development.  Potential regulator of presenilin.  May have a role in egg laying.  Regulates zyg-1 levels (possibly redundantly with lin-23) to control centrosome duplication during mitosis.  Negatively regulates lin-45 activity and protein stability, probably by targeting it for ubiquitination and proteasomal degradation.
What are the official names of this protein?
F-box/WD repeat-containing protein sel-10, Suppressor/enhancer of lin-12 protein 10.
What are the subcellular locations of this protein?
Cell projection, axon. Cytoplasm. Note=Expressed throughout the axon throughout development.
Protein: NEP1_PYRAB
Sequence: MSEKKRLHLIIADAELETVPEQILDHPAIVNYAKRRKRKPEKIILDSTYHHAALKQLEDGERRGRPDIVHICLLNALDSILNKEDRLRVYVHTRNDYVIYIKPETRLPRNYNRFIGLMESLFEKGAVPEDLELLRLERKTLQELINEINPDAVFVMHEEGELMIPKNFGKLLDKFKKPAVIIGGFPHGDFRSRVEGVKISLYKEPLMAWTIVNEVIVSYEWEVIKKFSTKFI
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA (By similarity).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: SYP_BAUCH
Sequence: MRTSQYLLSTIKEIPLDAEVISHQLMLRAGIIRQLASGLYTWLPTGLRILRKVENIVREEMNNIGAIEVSMPIVQPANLWLESGRWGQYGPELLRFTDRSTRQFLLGPTHEEVITDLIRNEVKSYKQLPLNLFQIKTKFRDEVRPRYGVMRSREFIMKDAYSFHTSQQSLQATYDLMYYTYNTIFNRIGLDVRTVQADPGSIGGHLSHEFLALVSNYEDQMLLIDASHKATERNLPSENLQLVDAPGIYTLTELVKLFNLPIEKIAQIIIVHAQQNALYPLVALMVRGDHSINYAQVEKLPQVASPLVFATEDEIRLAIGVGSSSLGPINLPLPLIIDHSVAVMSDFVAGANIDGKYFFGINWERDLSLPEVANLTNQNISVSQPQRLHRTNWIEVGHIFQLGSKYSKVMKATVQGEDGNNMIMTMGCYGIGITRVVAAAIDKYNDKQGLLLPVSIAPFQVAIIPINLHKSLLVQTVAEQLYNQLSIRKIDVLLDDRKERPGVMFADIELIGIPHIIIIGDRNLAVQKIEYKNRSNGEKKLMNLSIIVDWIVAKLNS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIPL1_ARATH
Sequence: METLWTLLYLLEPAPATLIVTAVTVTFASAFRALNYGKEMERNRDFSEASITLDSSQALMIPVMSSCSLLLMFYLFSSVSQLLTAFTAIASVSSLFYWLSPYAVYMKTQLGLSDPFLSRCCSKSFTRIQGLLLVACAMTVVAWLISGHWVLNNLLGISICIAFVSHVRLPNIKICAMLLVCLFVYDIFWVFFSERFFGANVMVAVATQQASNPVHTVANSLNLPGLQLITKKLELPVKIVFPRNLLGGVVPGVSASDFMMLGLGDMAIPAMLLALVLCFDHRKTRDVVNIFDLKSSKGHKYIWYALPGYAIGLVAALAAGVLTHSPQPALLYLVPSTLGPVIFMSWRRKDLAELWEGPALSNPIEKSHEIEI
What is the function of this protein?
Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.
What are the official names of this protein?
Signal peptide peptidase-like 1, AtSPPL1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22B family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: EX7S_ALKMQ
Sequence: MAKIKFEEGIKKLEEIINQLENKEQGLDDALELFQEGVRLYRICNEKLTEAEEKISVMIEEGNQLVERPFEGGEE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_PSYWF
Sequence: MSNVPSELKYVASHEWLRLEDDGTVTVGITDHAQEALGDIVYVELPDVGDTVAVDDEVAVVESVKAASDVYAPLTGEVVAINEALEDDPEVINTDPYGEGWMYRIKPDNADDFESLLSAEEYQAEL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: IFI75_MUSCR
Sequence: MFTLTKALEKALLQHFIYMKVNIAYAINKSFPFFETLRDNSFITERMYKESLEACQNLVPLSKVVHNILTSLEQTFQPSVLLTLFSQVNLREYPSLVAIFRSFRNVGYTYEEKNRPPPTLLEDLANPAEGCSLQTLLPPPRPQLSLPSHLSSAPRVCDPRATAQPITEILDEQPSPSPQAVPLPGCIQEGKTIPVSSRDHQRKDKEDSREMPHSPSGPESVVKDDSPAANDLEMAQEVLCTPANKKARRKKRLNWSNSKRGRQKKKPRQDEMMGVASPGHGVQEKIKAVVSRRTLWKDDSSTNVKEVTKILRARMRCAQTSNSQEISKEASKTSGRKRHGKRTSTAGKTTQVPGKTKNDAVDFLSPTFPVTCGKANGTLFQEKLKQGVSKKCIQNEAGDWLTVKEFLNEGRRATSKDWKKAIRCNGETLRQLEQKGLLFCTKSKPQKKGA
What are the official names of this protein?
Interferon-induced protein 75.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAB_ANASK
Sequence: MSDLVPLSRKPAPAAGGPAPSPAAPPRKVYVHTFGCQMNESDSDRMVELLGRHAYARAASADEADLILLNTCAVREKAEQKLLSALGRYREVKARRGALIAVSGCVAQQEKDRLLARVPYVDFVFGPDNIGRLPEMVERARDERFAETGWMDSEEYVFPRADPEAARGRVTAFVTAMKGCDNVCAFCIVPHTRGREVSRPFPDVVAECAALAGVGVREVTLIGQNVNSYTGGCTFADLLRRVAAVPGIDRIRFTTSHPHDLSDALVEVFRDEPKVMPHFHLPVQSGSDAVLRRMRRDYSVAEYLDRFDRLRAARPGIAITTDFIVGFPGETDADFEASLALLERARFEQSFSFVFSPRPHTVAAVRLGSAPEWRDVPREAAVARLERLLAAQRRIAGEILAGELGKVVEVLVEGPSDEPGERLGRTPENRVVHLAADEAAAPAGARVAVRITRAGGSSLSGTLA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.