PharMolix/UniProtQA huggingface dataset:
Protein: OBG_NEIMB
Sequence: MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGSVWAEADENTNTLVEYRFVKRYQAKNGEKGHGSDRYGAGADDIVLKMPVGTLIRDLDTGETVADLTYHGQRVCLAKGGKGGLGNIHFKSSVNRAPKQSTPGEEGEARSLQLELKVLADVGLLGMPNAGKSTLITAVSAARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLIEGAAEGAGLGHRFLKHLSRTGLLLHVVDLAPFDETVNPAEEALAIINELRKYDEELYGKPRWLVLNKLDMLDEEEAQTRTAAFLEAVGWDYPKPDDRFQFDMETPRLFQISALTHQGTQELVHQINQYLTEKKRIEAEKAEAEKAAANVEIIEQQPKTDTGVFKPE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA_I97A1
Sequence: MEDFVRQCFNPMIVELAEKTMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRAMAWTVVNSICNTTGVDKPKFLPDLYDYKENRFTEIGVTRREVHIYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFKPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWREPNIIKPHEKGINPNYLLAWKQVLAELQDIENEDKIPKTKNMKKTSQLMWALGENMAPEKVDFEDCKDIDDLKQYHSDEPELRSLASWIQNEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRRTNLYGFIVKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGEMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSIKEKDMTKEFFENRSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYSSPQLEGFSAESRKLLLIVQALRDNLEPGTFDLEGLYGAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: AROC_STUS1
Sequence: MSGNTYGKLFTVTTAGESHGPALVAIVDGCPPGLELSLDDLQRDLDRRKPGTSRHTTQRQEADEVEILSGVFEGRTTGCPIGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLATLGIQVRGYMSQLGPIEIPFKTWDSVEQNAFFSPDPDNVPELEAYMDQLRRDQDSVGAKITVVAEGVPPGLGEPIFDRLDAELAHALMSINAVKGVEIGAGFASVAQRGTEHRDELTPQGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTPGRSIDVNGEAVDVITKGRHDPCVGIRATPIAEAMMAIVLLDHLLRHRAQNADVQVTTPVLGQL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: KORA_METTM
Sequence: MTEEYFIQGNDACARGAISAGCRFFAGYPITPSTEIAEEMAVLLPGEGGVFVQMEDEIGALGAVIGAVWGGVKGMTATSGPGFSLMQEHVGYAAMTETPLVIVDVQRGSPSTGQPTMASQSDMMQARWGSHGDYEIIALSPSSVQECFDFTVRAFNLAEEYRVPVVVLSDEIVGHMREKITIPDKVEIRKRKSPTSPPGEFIPFKPQGDFVPEMPAFGDGYRVPVTGLTHDERGYPDASNPEGHEKLVKRLCDKILNHRDKIVDVQKGWTDDADITVISYGAPSRSVATAVKMARSEGVRAGYIKINTPWPFPETEIREAAESSRKLLVVEMNLGQMFYEVQRVASGMAEVELLPKIGGEIHRPDEILNKIMGMK
What are the official names of this protein?
2-oxoglutarate synthase subunit KorA, 2-ketoglutarate oxidoreductase alpha chain, KOR, 2-oxoglutarate-ferredoxin oxidoreductase subunit alpha.
Protein: TIG_VIBCM
Sequence: MQVTVETLEGLQRRLNITVPAANIEDAVAAELRNIAKNRRFDGFRKGKVPMKMVAKMYGKAVRQDVLGEVMQRHFIEAIVKEKINPAGAPTFAPVEIGEGKDLVFTATFEVYPEVELKGLENIAVEKPAAEVTDADVAEMLETLRKQQATWKEVDEAAENGKRVSIDFVGSIDGVEFEGGKAENFPLEMGAGRMIPGFEDGIVGKTKGMEFVIDVTFPEDYHAENLKGKAAKFAIKVNKVEARELPELNDEFVARFGVAEGGVDALKAEVRKNMERELKQAIKARIKEQAIEGLVKENEIQVPSALIDQEINVLRQQAAQRFGGNVEAAAQLPRELFEEQAKRRVVVGLLLGEVIRTHELKADEEKVKALITEMATAYEDPSEVVSYYEQNQQLMNNMRNVALEEQAVDAIIAKAKVTEKAISFSELMNPVAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RK14_BUXMI
Sequence: MIQPQTYLNVADNSGARKLMCIRIVGASNRRYAHIGDVIVAVIKEAVPNMPLERSEVIRAVIVRTCKELNRGNGMIIRYDDNAAVVIDQEGNPKGTRVFGAIARELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AP1G2_MOUSE
Sequence: MVVHSLRLQDLIEEIRGAKTQAQEREVIQKECAQIRASFRDGDPLQRHRQLAKLLYVHMLGYPAHFGQMECLKLIASPRFTDKRVGYLGAMLLLDERHDSHLLITNSIKNDLSQGNQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILTAVHMIRKDPELSGIFLPPCTKLLRERHHGIQLGTVTLITELCERNPAALRHFRKVVPQLVQILRTLVTTGYSTEHSISGVSDPFLQVQILRLLRILGRNHEESSETMNDLLAQVATNTDTSRNAGNAVLLETVLTIMAIHSAAGLRVLAVNILGRFLLNNDKNIRYVALTSLLQLVQSDHSAVQRHRSTVVECLQETDASLSRRALELSLALVNSSNVRAMMQELQAFLESCPPDLRADCASGILLAAERFAPSKRWHIDTILHVLTTAGAHVRDDAVANLTQLIGEAEELHTYSVRRLYSALAEDISQQPLVQVAAWCIGEYGDLLLEGNCEETEPFQVEEEDVLALLEKVLQSHMSLPATRGYAITALMKLSTRLRGDNNRIRQVVSIYGSCVDLELQQRAVEYNTLFQKYDHMRAAILEKMPLVERGDPHVKEGGKEKQTEAQPLEVTAPAPTEPQATKLLDLLDLLGDTSEPLSSGHAQHLPPQTPSPGEALIHLLDLPCTPPPPAPIPSVRVFEREGLQLDLSFMRPLETPALLLVTATTTNSSKEDVTHFVCQAAVPKSFQLQLQAPSGNTIPAQGGLPITQVFRILNPNQAPLRLKLRLTYNHSGQPVQEIFEVDNLPVETWQ
What is the function of this protein?
May function in protein sorting in late endosomes or multivesucular bodies (MVBs).  Involved in MVB-assisted maturation of hepatitis B virus (HBV).
What are the official names of this protein?
AP-1 complex subunit gamma-like 2, Gamma2-adaptin, G2ad.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Mainly localized to perinuclear vesicular structures. Colocalizes with HBV major surface antigen L and HBV core protein C in CD63-containing compartments. Colocalizes with HBV major surface antigen L to cis-Golgi-like structures.
Protein: NPTN_HUMAN
Sequence: MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLRQRNTN
What is the function of this protein?
Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK.  May also regulate neurite outgrowth by activating the FGFR1 signaling pathway.  May play a role in synaptic plasticity (By similarity).  Also acts as a chaperone for ATP2B1; stabilizes ATP2B1 and increases its ATPase activity (PubMed:30190470).  Promotes localization of XKR8 at the cell membrane (PubMed:27503893).
What are the official names of this protein?
Neuroplastin, Stromal cell-derived receptor 1, SDR-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Postsynaptic density.
Protein: TRPB_PHOV8
Sequence: MKTYQVNKEGYYGEFGGAYIPEILHRCVEELQNAYSKVLESEGFKQEFHQLLRDYVGRPSPLYLANRLSKKYGCKIYLKREDLNHTGAHKINNAIGQVLLAKRMGKKRIIAETGAGQHGVATATVCALMNMQCIVYMGKTDVERQHINVEKMKMLGAEVRPVTSGNMTLKDATNEAIRDWCCHPADTYYVIGSTVGPHPYPDMVARLQSVISEEIKKQLKEQEGREYPDYLMACVGGGSNAAGTIYHYIDDERVQIVLAEAGGKGIDTGFSAATIQLGKMGIIHGAKTLVIQNEDGQIEEPYSISAGLDYPGIGPMHANLAKQQRALVLAINDDEAIRAAFELTRLEGIIPALESAHALGALDKMRFKPTDIVVLTVSGRGDKDIETYLKESGTRTSLQ
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: Y2700_PHOLL
Sequence: MNLNDIALTGLIVLMLAFAVYDEFVVNFLKGKTHLQIKLKRKHKIDALIFIILILIVVYNNITVYGSRLTTYLLLFTILVTIYIAYIRSPKLFFKNNGFFYANTFISYSRIKTMNLSEDGILVIGLENKKLYISVSQIDDLERIYKFLIENR
What are the official names of this protein?
UPF0266 membrane protein plu2700.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IOVO_PENJC
Sequence: FAPVNVDCSDHPKPACLQEQKPLCGSDNKTYDNKCSFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: HXA2_MOUSE
Sequence: MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGVGGRPKSSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALPPAAASTGPACLGHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKFKNLEDSDKVEEDEEEKSLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQTFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDSPEAIEVPSLQDFNVFSTDSCLQLSDALSPSLPGSLDSPVDISADSFDFFTDTLTTIDLQHLNY
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A2, Homeobox protein Hox-1.11, Hox1.11.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Proboscipedia subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14_DECAR
Sequence: MAKLALINREEKRRKLVAQYAKKRAALEAIITNVSLSDEERYEARLKMQALPRNSSPSRLRNRCQLTGRPRGVFRKFGLCRHKIRELAFNGEVPGVVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: SECA_AZOC5
Sequence: MLGGLARKIFGSANDRRVRGYRPSVEAINKLEPELETLTDEQLRERTVMFRQQLAEGKTLDDLLVPAFATVREAAKRVMGMRHFDVQLIGGMVLHDAGIAEMRTGEGKTLVATLPVYLNALAGKGVHVVTVNDYLARRDAEWMAKVYGFLGLTTGIIVHGLDDDQRRAAYACDVTYATNNELGFDYLRDNMKYERAQMVQRPHYFAIVDEVDSILIDEARTPLIISGPLDDRSDFYNTIDKFIPRLSKGDYEVDEKQRSVAMTEAGMEKMEQMLTEAELLKSGSLYDIENVSIVHHVNQALRAHSLFQRDKDYIVRNDEVVIIDEFTGRMMPGRRYSEGLHQALEAKERVTVQPENQTLASITFQNYFRLYERLGGMTGTAATEAAEFADIYKLDVVEIPTNRKVQRIDDDDEVYRTNREKFDAIVKLIQECAARKQPVLVGTTSIEKSELLAERLKQAGMRQKDFSDRAAFTGSSDGKSFAVLNARYHEQEAFIVAQAGVPGAVTIATNMAGRGTDIQLGGNAEMRISEELADLPAGPEREAAEAKIREEIAALKQEALAAGGLFVLGTERHESRRIDNQLRGRSGRQGDPGHSKFFLSLEDDLMRIFGSDRLEGMLKRLGLQEGEAIIHPWINRALEKAQQKVEARNYDMRKNVLKYDDVLNDQRKVVFEQRLELMNDEDVAETVVDMRHDVITDLVAKYIPVNSYPEQWDVKGLDFAVRDVLTLALPIEDWAKEEGIAGPEVTERIIQKADEWMASKSAQYGPELMRYVEKSILLQTLDHLWREHIAMLDHLRQVIGLRGYGQRDPLQEYKSEAFQLFSAMLGRLREIVTAQLMRVEIVSTPQPTELPPMEAHHIDASTGEDELASAGAALSARPELALATEVPAADRDPNDPSTWGKVGRNEPCPCGSGKKFKHCHGRFA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MURQ_LACLM
Sequence: MIDLSTLTTERRNDETFNLDQMTVKEALVKMNNEDKKVAYAVEEALPNIEPVISSAIEAFNKGGRLIYMGAGTSGRLGVLDAAECVPTFGVPATQVVGLIAGGDKAMTVAVEGAEDSLELGRQDLIDLNLSENDLVLGIAASGRTPYVIGALDYAKEIGAKRASLSCNLNAEISKHAEFPIEVDCGPEFLTGSTRLKSGTAQKLILNMISTISMIGIGKVYNNLMVDVKPTNEKLVERSKRIIMQATDCTYEEAEEKFNEANQDVKLAIVMLLTDCAAEEGKTKLVKANGFVKNTLN
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: RS3_PYRAE
Sequence: MSAPQRRLPVYKKILEENKKKWMIKEFLEYRLSKYGYIDSEILKTPLGTRIVIYAERPSRIIGRKGAIVKEISNILTTKLGVENPQIDVIDISKIEAPEMFPKVVAYRIANAMAKGVRFRRVMFVAIRQLMEAGAKGFEIVVSGKLSTERARFEKQTYGKLYKIGYDAKNRVRRAVVHVLLKPGIYGIEVRIAPATLQYSDEYKIKPPVRPEAVQQQS
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TEX22_MOUSE
Sequence: MDSRQQRPQRKTLQWQLAQEQRQQSPPQGLAVASSQPDTKSKPQDDLQTQDWVCEPQELRRPGSRWNISIDERRRLALQRMQERTDTARAPSGDPLGLHPEGQQTETSPSTQSVPTPPLQACETMADPLQDIAHVLAELMSEGVERDVLISQPLRSTENSNAFQDFLAQDAPLWKDENFEAQTSRWPHS
What are the official names of this protein?
Testis-expressed protein 22, Testis-expressed protein of 22 kDa.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Localizes in the acrosomal region of early elongating spermatids. During late stages of elongating spermatids, no longer detected in the acrosomal region, while it mainly localizes in the cytoplasm. Incorporated into the midpiece of spermatids and is also present in the mitochondrial sheath of mature spermatozoa.
Protein: PSAJ_NYMAL
Sequence: MRDIKTYLSVAPVLTTLWFGSLAGLLIEINRLFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HS110_CAEEL
Sequence: MSVLGFDIGNLNCYIGVARQGGIEVITNDYSLHATPACVSFGPKDRSMGVAARQAVTTNIKNTVINFKHLIGRKFSDPVAQRFIPFIPCKVVKLPNDDIGVQVSYLGEPHTFTPEQVLAALLTKLRTIVESQLSDVKKVSDCVLAVPSYFTDVQRRAVLSAIQYAGLNSLRIVNETTAIALAYGIYKQDLPEEDAKSRNVVFLDIGHSSTQASLVAFNRGKLQMVNTSYDLESGGIWFDALIREHFRKEFKTKYGIDAATSPRPWLRLLDECERVKKQMSANQTPIPLNIECFMEDKDVTGKMQRQEFEDLAAPIFNRIKQVLINLFADGVSIKPEEIDEIEIVGGSSRIPMIREIVKDLFGKEPKTTMNQDEAVARGAAMQCAILSPTFRVREFAIKDTQPYRIRLSWNSTGENGGENDVFSPRDEVPFSKLVSLLRSGPFNVEAHYAQPNVVPHNQVHIGSWKVNGARPGADGGNQKVKVKVRVNPDGIFTIASATMYEPRIVEEVPAEAMEVDGDAKTEAPAEPLEPVKKTKLVPVDLEVIESIPVSYDVQKFHNLELQMQESDAREKAKADAKNSLEEYVYEMRDKVSDQYAEFITPAAADEFRSVLTSTEDWLYDEGEDAERDVYEKRLSELKAVGTPVVERYRESETRKPAFDSFDQSIMRVRKAYEDYANGGPTYAHLDSKEMEKVINAIEDKKKWLDEARHKQETRSKTDAPVVFTEEILQNKNVFENVVNPILNKKKPAAPAPPKKEEPQPAAGDQPQSQPGEMDVD
What are the official names of this protein?
Heat shock protein 110.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NU155_MOUSE
Sequence: MPSVLGSMMVASTSAAASLQEALENAGRLIDRQLQEDRMYPDLSELLMVSAPNSPTVSGMSDMDYPLQGPGLLSVPSLPEISTIRRVPLPPELVEQFGHMQCNCMMGVFPPISRAWLTIDSDIFMWNYEDGGDLAYFDGLSETILAVGLVKPKAGIFQPHVRHLLVLATPVDIVILGLSYANVQTGSGILNDSMCGGMQLLPDPLYSLPTDNTYLLTITSTDNGRIFLAGKDGCLYEVAYQAEAGWFSQRCRKINHSKSSLSFLVPSLLQFTFSEDDPIVQIEIDNSRNILYTRSEKGVIQVYDLGHDGQGMSRVASVSQNAIVSAAGNIARTIDRSVFKPIVQIAVIESSESLDCQLLAVTHAGVRLYFSTCPFRQPLARPNTLTLVHVRLPPGFSASSTVEKPSKVHKALYSKGILLMTASENEDNDILWCVNHDTFPFQKPMMETQMTTRVDGHSWALSAIDELKVDKIITPLNKDHIPITDSPVVVQQHMLPPKKFVLLSAQGSLMFHKLRPVDQLRHLLVSNVGGDGEEIERFFKLHQEDQACATCLILACSTAACDREVSAWATRAFFRYGGEAQMRFPATLPTPSNVGPILGSPMYSSSPVPSGSPYPNPSSLGTPSHGAQPPTMSTPMCAVGSPAMQAASMSGLTGPEIVYSGKHNGICIYFSRIMGNIWDASLVVERVFKSSNREITAIESSVPVQLLESVLQELKGLQEFLDRNSQFSGGPLGNPNTTARVQQRLVGFMRPENGNTQQMQQELQRKFQEAQLSEKISLQAIQQLVRKSYQALALWKLLCEHQFSVIVGELQKEFQEQLKITTFKDLVIRDKEVTGALIASLINCYIRDNAAVDGISLHLQDTCPLLYSTDDAVCSKANELLQRSRQVQSKTERERMLRESLKEYQKISNQVDLPSVCAQYRQVRFYEGVVELSLTAAEKKDPQGLGLHFYKHGEPEEDVVGLQTFQERLNSYKCITDTLQELVNQSKAAPQSPSVPKKPGPPVLSSDPNMLSNEEAGHHFEQMLKLAQRSKDELFSIALYNWLIQADLADKLLQIASPFLEPHLVRMARVDQNRVRYMDLLWRYYEKNRSFSSAARVLSKLADMHSTEISLQQRLEYIARAILSAKSSTAISSIAADGEFLHELEEKMEVARIQLQIQETLQRQYSHHSSVQDAISQLDSELMDITKLYGEFADPFKLAECKLAVIHCAGYSDPILVHTLWQDIIEKELNDSVALSSSDRMHALSLKLVLLGKIYAGTPRFFPLDFIVQFLEQQVCTLNWDVGFVIQTMNEIGVPLPRLLEVYDQLFKSRDPFWNRVKSPLHLLDCIHVLLTRYVENPSLVLNCERRRFTNLCLDAVCGYLVELQSMSSSVAVQAITGNFKSLQAKLERLH
What is the function of this protein?
Essential component of nuclear pore complex.  Could be essessential for embryogenesis.  Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.
What are the official names of this protein?
Nuclear pore complex protein Nup155, 155 kDa nucleoporin, Nucleoporin Nup155.
What is the protein family that this protein belongs to?
Belongs to the non-repetitive/WGA-negative nucleoporin family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing back into a punctate nuclear surface localization at the end of mitosis.
Protein: CAPSD_HBVF1
Sequence: MDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTASALYRDALESPEHCTPNHTALRQAILCWGELMTLASWVGNNLEDPAARDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSPASQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TIG_LISMF
Sequence: MSVKWEKQEGNVGKLTFEIEQEKVKEGLDRAFVKVRKTLNVPGFRKGKVPRQIFNQRFGEEALFQDALDILLPEVYSAAIDEAGIDPVDTPQVNIESMEKGETWVLTAEVTVKPEVKLGDYKGLEVEKRETELTTEELEAELKQLQERQAELVVKEDAPAENGDTVILDFEGFKDGVAFEGGQAENHSLELGSGQFIPGFEEKLVGLKAGDEADIELTFPEEYHAEDLAGQPVVFKVKLHEIKTKEVPALDDELAKDIDEEVETLDELKEKISKRLQEAKEESVAQAKQEEVIAKAVENAEVDIPHAMVHHEADHLMNHFAQDLQAQGLTPELYYQFTGQTEEAMHAQMEKDAEKRVKMNLVLEAIAEAENIEPTEEAIDEEISTLAEKYGMEKDAVRAALGDMSELKSDLKIRKAIDVLLDSAVEK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RS12_BACLD
Sequence: MPTINQLVRKGRVSKVETSKSPALNKGYNSFKKEHTNVSSPQKRGVCTRVGTMTPKKPNSALRKYARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVENRAQGRSKYGTKRPKKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.