PharMolix/UniProtQA huggingface dataset:
Protein: YBY8_YEAST
Sequence: MEKDQIQPRVLESVDTNSLSLLSSNTSSNMNSNTNNKLSIIASDISTGSVLSRPLTPPVVQDIENNSMLQWQFEKKEFIFDSNSTPSKQAKPLQRNSPYQGNSQSENQNQQLLNVRKRRSQLIGAKPKIPSKLYQSVSKLDLIDDKSFTSLPIAPPCNIETNEDDSGNNEYNNNKKRPRLNPVNELRVHNNKRNRYVSYGPSLDTKNYELTENTSQDIPPLVLVEDYIPYTQSKSTKKMVSISDLKSKLSKRRDNHIPLRVKNSYSEINKETNRNSFEPNSLTLIPHILRNTEENRDESNNPLDFIKEEIEISDISIPNSIENMVVNLVNIPSSNKSYDDLYLSELNVHSQLRKCVICEKALYEISSRLLNSGYYKEIVCEQCTVRYEEAAKIFENCEFESSMDESNLSSGTFSDLENSAEPFHLSTDVPKKINRHIEDNKIDLKKEISKKKDSFSKELIERLQLQLLENDKSIKHHFNKDAMGSKSMNWFLEARRKLKWKWRINGLLPHFLRNQNSDRLNFQP
What are the official names of this protein?
Uncharacterized protein YBR138C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_XANCB
Sequence: MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVSLYGFLREGERRLFRDVQKVTGIGAKIALAVLSGVTVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQLGYKPAEAARMAREAGAEGDEVATVIRKALQAALR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RDRP_TMVB
Sequence: MAYTQTATTSALLDTVRGNNSLVNDLAKRRLYDTAVEEFNARDRRPKVNFSKVISEEQTLIATRAYPEFQITFYNTQNAVHSLAGGLRSLELEYLMMQIPYGSLTYDIGGNFASHLFKGRAYVHCCMPNLDVRDIMRHEGQKDSIELYLSRLERGGKTVPNFQKEAFDRYAEIPEDAVCHNTFQTCEHQPMQQSGRVYAIALHSIYDIPADEFGAALLRKNVHTCYAAFHFSENLLLEDSYVNLDEINACFSRDGDKLTFSFASESTLNYCHSYSNILKYVCKTYFPASNREVYMKEFLVTRVNTWFCKFSRIDTFLLYKGVAHKSVDSEQFYTAMEDAWHYKKTLAMCNSERILLEDSSSVNYWFPKMRDMVIVPLFDISLETSKRTRKEVLVSKDFVFTVLNHIRTYQAKALTYANVLSFVESIRSRVIINGVTARSEWDVDKSLLQSLSMTFYLHTKLAVLKDDLLISKFSLGSKTVCQHVWDEISLAFGNAFPSVKERLLNRKLIRVAGDALEIRVPDLYVTFHDRLVTEYKASVDMPALDIRKKMEETEVMYNALSELSVLRESDKFDVDVFSQMCKSLEVDPMTAAKVIVADMSNESGLTLTFERPTEANVALALQDQEKASEGALVVTSREVEEPSMKGSMARGELQLAGLAGDHPESSYSKNEEIESLEQFHMATADSLIRKQMSSIVYTGPIKVQQMKNFIDSLVASLSAAVSNLVKILKDTAAIDLETRQKFGVLDVASRKWLIKPTAKSHAWGVVETHARKYHVALLEYDEQGVVTCDDWRRVAVSSESVVYSDMAKLRTLRRLLRNGEPHVSSAKVVLVDGVPGCGKTKEILSRVNFDEDLILVPGKQAAEMIRRRANSSGIIVATKDNVKTVDSFMMNFGKSTRCQFKRLFIDEGLMLHTGCVNFLVAMSLCEIAYVYGDTQQIPYINRVSGFPYPAHFAKLEVDEVETRRTTLRCPADVTHYLNRRYEGFVMSTSSVKKSVSQEMVGGAAVINPISKPSHGKILTFTQSDKEALLSRGYSDVHTVHEVQGETYSDVSLVRLTPTPVSIIAGDSPHVLVALSRHTCSLKYYTVVMDPLVSIIRDLEKLSSYLSDMYKVDAGTQXQLQIDSVFKGSNLFVAAPKTGDISDMQFYYDKCLPGNSTMMNNFDAVTMRLTDISLNVKDCILDMSKSVAAPKDQIKPLIPMVRTAAEMPRQTGLLENLVAMIKRNFNAPELSGIIDIENTASLVVDKFFDSYLLKEKRKPNKNVSLFSRESLNRWLEKQEQVTIGQLADFDFVDLPAVDQYRHMIKAQPKQKLDTSIQTEYPALQTIVYHSKKISAIFGPLFSELTRQLLDSVDSSRFLFFTRKTPAQIEDFFGDLDSHVPMDVLELDISKYDKSQNEFHCAVEYEIWRRLGFEDFLGEVWKQGHRKTTLKDYTAGIKTCIWYQRKSGDVTTFIGNTVIIAACLASMLPMEKIIKGAFCGDDSLLYFPKGCEFPDVQHSANLMWNFEAKLFKKQYGYFCGRYVIHHDRGCIVYYDPLKLISKLGAKHIKDWEHLEEFRRSLCDVAVSLNNCAYYTQLDDAVWEVHKTAPPGSFVYKSLVKYLSDKVLFRSLFIDGSSC
What is the function of this protein?
Is a methyltransferase active in RNA capping and an RNA helicase.  Methyltransferase displays a cytoplasmic capping enzyme activity.  This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus.  Helicase region probably exhibits NTPase and RNA unwinding activities (Potential).  It also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  May mediate silencing suppression through either inhibition of HEN1-mediated siRNA or siRNA demethylation (By similarity).
What are the official names of this protein?
Replicase large subunit, 183 kDa protein, RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: RSMH_LACAC
Sequence: MKFKHTSVLLHETIDNLKPKNDGLYVDATFGGGGHAKYLLSKIDTGTLIGFDQDEYAIKSAELNFANLLKPDSEPKLQLVHDNFSNLEENLVKLGYTDGIDGIYYDLGVSSPQFDQADRGFSYRYNARLDMRMNQDQDLDAYQLVNTLSQKELADILYQYGDEKFSRQIAHKIVEKRKEKPIVTTFELVDIIKDAIPAYARRTGGHPAKKSFQALRVAVNHELDVLQASLEEAIKVLRPGGRISVITFQSHEDKIVKKIFKKYSEVEVPRGMPFIPDDMKPTLKLVNRKPIVASDSELENNNRSHSAKLRVAEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAPB_NEOGA
Sequence: MRSQDPSRRLSRRLWTLFALALCLVTGTVALAQTVPQLSGRPSPMQNTGADPLPRWIVDDIQKMRNYPDQPPVIPHSIEGYQLSVNTNRCMSCHRRELTEGSGAPMISVTHYMNREGQMLADVSPRRYFCTACHVPQADTRPLVDNTFKDMSELGFKPAGSGQ
What is the function of this protein?
Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm.  Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor.
What are the official names of this protein?
Periplasmic nitrate reductase, electron transfer subunit, Diheme cytochrome c NapB.
What is the protein family that this protein belongs to?
Belongs to the NapB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GPX1_SYNY3
Sequence: MTAQANNTIYGFSANALDGSPVALRDFEGKVLLIVNTASQCGFTPQYQGLQALYNRFGDRGFTVLGFPCNQFGQQEPGGSGEIKNFCETRYGVTFPLFEKVEVNGPNAHPLFKFLTAASPGMAIPFLGGAEDIKWNFTKFLVDRQGKVVKRYGSIAKPDEIAADIEKLL
What is the function of this protein?
Hydroperoxy fatty acid reductase essential for the removal of lipid hydroperoxides under normal and stress conditions, leading to the protection of membrane integrity.
What are the official names of this protein?
Hydroperoxy fatty acid reductase gpx1.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: Y5934_DICDI
Sequence: MQEEKNKEILLKDIENQIPYSKPFGVYDQLKKRIFRFILGVILLGVIIESITLLVVYFKDKK
What are the official names of this protein?
Putative uncharacterized transmembrane protein DDB_G0287865.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FLHD_SALTY
Sequence: MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMANTLGALTLPQMVKLAETNQLVCHFRFDDHQTITRLTQDSRVDDLQQIHTGIMLSTRLLNEVDDTARKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways (Probable).
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_CALBD
Sequence: MNKVTTKTLFEKKQKGEKITMITAYDYTFAKIFDSCSVDILLVGDSLGMVILGYDSTIPVTMDDMEHHVRAVSRGAKYSMVVADMPFLSYHTTIEEAVKNAGRLIRAGAYAVKMEGCDDVYDKIEAVIKAQIPVMGHLGLTPQSVNIFGGYDLRAKEEAEAKKLVEDAKKLEKAGVFAIVLEKVPSHVAKEVQRSLNVPVIGIGAGPYCDGQVLVCYDMLGMYEDFKPKFVKRYAEVGNMIKDAVTRYIEEVKKGEFPGKEHSY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLMA_IDILO
Sequence: MAEQKRNRREEILQALAAMLETSPGQRITTAKLAANLGVSEAALYRHFPSKARMFEGLIEFVEDTLLTRINMIMDEEKNTLSRCHAILQLLLTFAERNPGITRVMTGDALMGEHDRLRGRMEDLFNRIESSIKQILREKAMREQQRFIVDEAVLANLLLSYADGKISQFVRSNFKRLPTEHFSAQWQVMEQQLISA
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NP106_SCHPO
Sequence: MESKEAKEKGVNTSDSKGSQIESSISDLREKSQHLFGVLLEPQVPVIQYGLNQLEEKARNLESKVLLTRDGDTKAHYLLAESGMNAEQTRQKIYSIHIHSPWDQLELDKKSLYEQPHTKLYNGQNVVASIENGYQSNVYEFQLRLMKNNGIAWENTKTEFMEDVGKLLHSKDNSGLGTSISMSLRPNLARPLLTASSVKSQSVRSLREVGSNLPIPTGSLTKIDGLNNQLSNDLTRSQTTNIFGFAEKASSFAAAVHKLNEARIRNQACHVWSLFASVSQMVNTEVIQLFDAWSLLAHMIDETRYGMGDFEARHLALDSSSAALAVEKNCIEGSLKYLENQFLSLIDLHLSDAGHITTVNSVEKVIAYSKLRFYKNGSWIKSTVSVVNDVPLWVVLFYLMRSGQLDAALQFVNTYSDDFEKLGRSFPLYFYSYAKNPSLPLPKQLRDRLQAEYGQLMKYAPEDPFKHAIYKLLGNCEPHRVSLPEVCVTSEDYMWIQLMFCRVNQNDVIDSNGGQSTNSLFNLYQLEKKIVAFGPRYFNPKNNTPTNYFLALLMCGEFERAISFLHTNYPVEATHFAVAMAYYGLLRTKNYEKNENILIYEADDVKINFPQLIIAYLKHLEYVDAAVYLDYIACIPLVPAYQACSINLTKILLLQSHEFSKFLGDIKPDTERTTGLLDLYLRLIPFDHDSLQKLYLEGAREADDDGRFGDSIILYHLLGDYDTVIGVAIKNLSQSIVSRGLWSIDSKESKNMHISSNVVASEAPDALAANLLAMYESNPKKSAKVSATNKKALKVLLKVVKVQKLYGQEKWDEVLQLIEHLDLLPINEVQAEFEPNEQIPPISARLRRRAFEFSTFQDEVLSVIPSLMYISMSSIKALYRTISKLPVVNEESKKKLQRLQFKGSMLVMFSTMIESRLSPQILEYLQAEQLTLL
What is the function of this protein?
Has a role in promoting mRNA export from the nucleus.
What are the official names of this protein?
Nucleoporin npp106, Nuclear pore protein npp106.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin interacting component (NIC) family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex.
Protein: TRUA_MESFL
Sequence: MFKFLITLEYDGSDFHGWIEQPKTSTIQGELNKAINRVTKNAVFKTIGASKTDTGVHAIDQKVLLDLGFNPKLDLFKKAINKALPETIKVRSIEEVKQDFNIRDVLYKEYSYTINDKEYNILSNRFELNWDFEEIDIDKLQNIFNLFIGEHEFKLFSGLNHKELDSNKITTIREIESIDVKRALDKVVITFKAKGFIRYQIRMIVQSALNCYLNKKISADEIKEKLQGKGNKPPFNAPAKGLKLNKIVFKS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MURD_MYCBP
Sequence: MSGLPRSVPDVLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAVRAVIR
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB6_GUITH
Sequence: MGKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCIGGITFTCFIIQVATGFAMTFYYRPTVAEAFASVEYIMTEVNYGWLFRSMHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVTLAVVTVSFGVTGYSLPWDQVGYWACKIVTGVPEAIPVVGSLLVELLRGSVSVGQATLTRFYSAHTFVLPVAAAVLMLTHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CPFC_LIMRD
Sequence: MKKNGLLLVNLGSPDTPTTPDVKRYLKEFLSDRNVIEMPPALWQPLLRGIILPTRSWRSATFYRNCWTKDGSPLIVYTERLVAKVQGLMPEWVVKMAMTYGKPKISDTITGMKKECQNITVLPLFPFFTKSTTQTVIDKVKDADPEAKIIDRFSAEEDYLDLLAKQIQTAWDRGKYDKLLISYHGIPTAMVNHGDPYRDETEAATAELIKRLDIPEKQIKMAYQSKFGPMPWLKPYLRNTLLNEAQLGHRDVLVVAPSFVADCLETLEEDQVQNYQVFRENGGNNLVMVPSLNDSPEFAQFITDLVQRKG
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_PROM0
Sequence: MGHKIHPSGLRLGITQEHRSKWFATSKTYPILLQEDFKIRTFIQKKYGAAGISDVLIARKADQLELELKTARPGVIVGRQGSGIEELRSGIQKTIGDRTRQVRINVVEVERVDADAFLLAEYIAQQLEKRVAFRRTIRMALQRAQRAGVLGLKIQVGGRLNGAEIARTEWTREGRVPLHTLRAEIDYATREANTTYGVLGIKVWVFKGEVLPKEEQTIPVGASPKRKASRRPQQFEDRSNENS
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MIAB_STRAW
Sequence: MSSIDRSQPVGVKTYEVRTYGCQMNVHDSERLSGLLEDAGYVRAPDGSDGDADVVVFNTCAVRENADNRLYGNLGRLAPMKTKRPGMQIAVGGCLAQKDRDTIVTKAPWVDVVFGTHNIGKLPVLLERARVQEEAQVEIAESLEAFPSTLPTRRESAYAAWVSISVGCNNTCTFCIVPALRGKEKDRRTGDILAEIEALVGEGVSEITLLGQNVNAYGSDIGDREAFSKLLRACGQIDGLERVRFTSPHPRDFTDDVIAAMAETPNVMPQLHMPMQSGSDTVLKAMRRSYRQDRYLGIIEKVRAAIPHAAITTDIIVGFPGETEEDFEQTMHAVREARFTQAFTFQYSKRPGTPAATMENQIPKEVVQARYERLVALQEEISWDENKKQVGRTLELMVAEGEGRKDGATHRLSGRAPDNRLVHFTKPDEEVRPGDVVTVEVTYAAPHHLLAEGPVLNVRRTRAGDAWEKRHIEKTAEAAKPAGVMLGLPKIGAPEPLPVATGSGCGCD
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRI_PYRHO
Sequence: MPELKVSAIKEGTVIDHIPAGKGLKVIEILGLSKLSNGGSVLLAMNVPSKKLGRKDIVKVEGKFLSEEEVNKIALVAPTATVNIIRNYKVVEKFKVEVPEVIEGILKCGNPNCITNYEYVTTKFYVISKNPLKVRCHYCERTMEEEEILANL
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: TRPB_LISMC
Sequence: MTYQAPDENGFYGKFGGRFVPETLMKAVKELDEAYRASKTDPAFQKELNYYLKEYVGRETPLYFAEQLTAHAGGAKIYLKREDLNHTGAHKINNTIGQALLARQMGKQKVVAETGAGQHGVATATVAALFNMECTIFMGEEDVKRQSLNVFRMELLGAKVVSVKAGSRTLKDAVNEALRFWVANVEDTHYIMGSVLGPHPFPEIVRDYQSVIGIEARKQHLEKEGKLPDAIVACVGGGSNAMGLFYPFVDDVSVQMHGVEAAGHGLETEFHAATISKGEIGILHGAMMDVLQDENGQILEAFSISAGLDYPGIGPEHSFFRDLGRAAYHSVTDDEAVEAFQLLCRTEGIIPALESSHAISYAVKLASQMRPEESMVVCLSGRGDKDVNQLKERLEGQIND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: XPOT_MAGO7
Sequence: MDAQIENAIQIAWDPQSDPSLKSQAFEFLQQLRADPSAWHICSTLFTKSPRSADVVRLVSLEIVNLAVQVQQLDAASLAFLKDSLLDYVRRTYGPGAQDEPDVPSLQNKLTQTLTYLFARLYKSGWETFLSDFLALTASSEGNPRQRDNVRGVTLYLRILGSVHDEIADNMLARQGNEGKRNAELKDAIRERDMRMVVESWQDLLSQYTGRDDAILEHTLKVMAKWVSWIDISLVITQDMLNLLFPLIGCVNPQGGADMVRDAAIEAFTEIAGKKMKPVDKTELISFLNLRQIISELVASPPLSQFRGTHRYDSDLAESVAKLVNVVVTDVVKVLEDGSVGEESRAKAGQHLQDFLPLLLRLFSDEYDEVCSTVIPSLTDILTFLRKVPELPDSYREMLRPIMDAIVAKMRFDETSHWFEGEEAEEEADFLELRKRLQNLQKSVAAVDENLFIDVMSNLVATTLQNLDERGAQMDWRDIDLALHELLQFGELALPNQGLAAKSQPSSNAAERLNVIMRKLVESSIADFPHPAVLLQYMEVCVRYCVFFETNHSYIPRVLENFVRLVHYDLTRFRVRSWYLFHRFVKQLRAQVGNVAETIIQSIADLLPIKAEVSAEDGSEDDMSSDQTDNSADAIFNSQLYLFEAIGYISSTSATPVDKQALYARSVMEPLFRDMENHLEKAKSGDAQAILQIHHVIMALGTLAHGFGDHAKPGHQRQAPDKLVSAEFARAAEAILIALGQLNSRMDIRAACRSAFSKLLNVLGSAVLPQLPQWIEGLLSQSSSKDEMAMFLRLLDQVVYGFKTEISDVLNLLLTPLLQRVFGGLAEPINGTDDEIQLGELRREYLTFLQIILDNDLGAVLVSETNQGFFESIISSVVTLAKTGGHVNMVASRLAFCTLYRIVGVWGGPDVANISANPSAPTGTPTPAIPGFDQFMIERFHPVCFEVLQDPQFNPSKDAQSKQVLNEIAALEQAIYVKTGNSFISHLQSSLFPALGIDGTEFLRCMTTSTDKKTFGNYLQNLIKNRR
What is the function of this protein?
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.  Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).
What are the official names of this protein?
Exportin-T, Exportin(tRNA), Karyopherin-beta, tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: CLPP4_PROM9
Sequence: MENYFVNSEKKHLIQSSISSYESIHKTIGAVPTVIEQSGRGERAFDIYSRLLRERIIFLGSGINDQVSDSLVAQLLFLEAEDPEKDIQIYINSPGGSVTAGMAIYDTMQQISPDVVTICFGVAASMGAFLLSGGAKGKRLALPNSRIMIHQPLGGAQGQAVEIEIQAKEILFLKKTLNSLLAEHTGQPLEKINEDTERDYFLSPSEAVEYGLIDKVIKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 4, Endopeptidase Clp 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_ECOLU
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_YERPN
Sequence: MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEANLSAKDIDAVAYTAGPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDDAAGEAFDKTAKLLGLDYPGGPMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFEDAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLRSNLNSELSVSVRPRWPLSELPKV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_SULIM
Sequence: MTSNEELLQNYCSILFTYKTIGISNLHLYYFRETEIKSLRQLINAEFAILQTCNRVEIYLYSNTNTISEINKMIQYLNNVHNEPIGNQARVICGKDSIKHLFLVASGADSLSIGEYEILSQIRSTIDMFKKLGFSGKYLQILFERAIKVGRKVREETSISKGKVGIYSLAIDEAKRQFNNFYDRKIVIVGAGEMGQKIANMLYNEGVKNVTIMNRTVEKAKQLALKFGYNYEKLDLDKLGSFDIAFISISHENLRLENKWNTLIVDITVPPLFTGNNVITLEELEKISKLNFKAREEELVKINKLVEDGIDELIYDYKKEIYSEFMSKIMKRVETIRENEIVRAYKELEKLGINNQQVKEILDLMTRSIIKKSFQPLFDNVRSLVFDGENSINYINFLIDIFKDGNIPIFETKKIKKKQISKRSSS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: BIOD_CLONN
Sequence: MSNGIFIVGTDTDIGKTFVTGGILYLLRKNGVNASYFKAALSGAIKVNERLIPGDTKFVSDLSGLNEEYSFLTPYVFETAVSPHLASKIENIPINLEVIKSSYLKVKEKYDYIVAEGSGGIVCPMVHNEKSTILLEDIIKLLDLDTLLVASAGLGSINHTVLTVKYIENAGLNIKGIIVNGYDENNICHRDNVKMIKKLTSKDIIALIPRIKDNNNHKEIKKVFDDLDYKKIKKCIGA
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELAD_ECO24
Sequence: MMVTVVSNYCQLSQKQLSQTFAEKFTVTEELLQSLKKTALSGDEESIELLHNIALGYDKFGKEAEDILYHIVRNPTNETLSIIRLIKNACLKLYNLAHTATNFPLKPTGPDNSDVLLFKKLFSPSKLMTIIGDEIPLISEKQSLSKVLLNDENNELSDGTNFWDKNRQLTTDEIDCYLQKIAANAKNTEVNYPTGLYVPYSTRTHLEDALNENIKSDPSWPKAVQLFPINTGGHWILVSLQKIVNEKNNTQQIKCVIFNSLRALGHDKENSLKRVINSFNSEFMGEMSNNNIKVHLTEPEIIFLHADLQQYLSQSCGAFVCMAAQEVIEQRESNSDSAPYTLLKNYADRFKKYSAEEQYEIDFQHRLVNRNCYLDKYGDARINASYTQLEIKHSQPKNRASGKRVS
What is the function of this protein?
Protease that can act as an efficient and specific deubiquitinating enzyme in vitro.  Does not possess desumoylating and deneddylating activities.  The physiological substrate is unknown (By similarity).
What are the official names of this protein?
Protease ElaD, Deubiquitinase, Deubiquitinating enzyme, DUB, Deubiquitinating protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C79 family.