PharMolix/UniProtQA huggingface dataset:
Protein: KDM5D_HUMAN
Sequence: MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLSKIVIEEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHPFDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPEEKEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCLSEVEACIAQVLGLVSGQVARMDTPQLTLTELRVLLEQMGSLPCAMHQIGDVKDVLEQVEAYQAEAREALATLPSSPGLLRSLLERGQQLGVEVPEAHQLQQQVEQAQWLDEVKQALAPSAHRGSLVIMQGLLVMGAKIASSPSVDKARAELQELLTIAERWEEKAHFCLEARQKHPPATLEAIIRETENIPVHLPNIQALKEALTKAQAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKALGLYQCDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLAPSLMASSPTSICVCGQVPAGVGVLQCDLCQDWFHGQCVSVPHLLTSPKPSLTSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVTALLRQLAELRQQLQAKPRPEEASVYTSATACDPIREGSGNNISKVQGLLENGDSVTSPENMAPGKGSDLELLSSLLPQLTGPVLELPEAIRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLDRIRTLLELEKFEHQGSRTRSRALERRRRRQKVDQGRNVENLVQQELQSKRARSSGIMSQVGREEEHYQEKADRENMFLTPSTDHSPFLKGNQNSLQHKDSGSSAACPSLMPLLQLSYSDEQQL
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'.  Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'.  May play a role in spermatogenesis.  Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8.  Suppresses prostate cancer cell invasion.  Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks.
What are the official names of this protein?
Lysine-specific demethylase 5D, Histocompatibility Y antigen, H-Y, Histone demethylase JARID1D, Jumonji/ARID domain-containing protein 1D, Protein SmcY, [histone H3]-trimethyl-L-lysine(4) demethylase 5D.
What is the protein family that this protein belongs to?
Belongs to the JARID1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DER_THEVB
Sequence: MALPIVAVVGRPNVGKSTFVNRLAGERDAIVHDEPGVTRDRTYRPAFWQDREFLVVDTGGLVFDDDSDFLPLIRQQAELALQEATAAIFVVDGQAGPTALDYEIAAWLRQLSLPVLVAVNKCESRQMGQVQAAEFWSLGLGEPYPISSIHGSGTGELLDQLITYLPAGETLPEAPEIQVAIAGRPNVGKSSLLNALIGSDRAIVSPISGTTRDAIDTVIEHGGTQYRFIDTAGIRKRTHVAYGPEMFSVHRAFKAIHRSDVVLLVLDALEEITEQDQRLAGHIADQGRACVLIVNKWDAVLDKDTYTINAYRDRLYQRLHFLEWADALFVSAHTGQRLEKIFAAVDAAVEQHRRRVTTAVVNDVIQEALHWHTPPATRQGRQGKIYYATQVATQPPTFAIFVNDAKLFKENYRRYIESQIRQQLGFRGTPIRLLWRSKKPREAAELVAR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RR14_DRIGR
Sequence: MARKSLIQRERKRQKLEQKYHLIRRSSKKEISKVSSLSDKWEIHGKLQSPPRNSAPIRLHRRCFSTGRSRGNYRDFGLSGHILRERFHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PDXT_METLZ
Sequence: MRIGVLALQGAFIEHIRMLERLGVETFEIRNLSDLKEIPDGLILPGGESTVMSKLLQDLGLFEKLRSLIMTGTPVMGTCAGLILLAKYIEGGSPSLGTMDITAVRNAYGRQLGSFQATAPFAGAGNIQMTFIRAPMITHVGKNVKVLAEVDGVVVAAREDNQLVLSFHPELGEDTFVHQYFLEMIAGTN
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: ZPT71_CAEEL
Sequence: MRLQLVALLFALVFNAFSHEHSHEHHHEGDGSEILTKVGWNDHSEELHDHHEHDHDHHDEQLIRKNHTSHREIQHSRLSTLKVWVFSLSAVVGISLAPCTLLFFIPAQHANGPFLKILLAFGAGGLLGDALLHIIPHSLSPHDHSHDHHDHNHSHKEHDHSHDHSNQLRVGTFVIAGILVFMMVEQLVRIIKGGHCHSHENGHIVADEHRHLNEHDHEHSEEKKQQVEGLKDVKASAYLNLVADFVHNVTDGLAIGASFSAGNTLGWITTLTVLLHELPHEVGDFAILVQSGFSKYQAIRLQAVTALGAITGCVFSLLVSNPGSLNNDADTSAIMPFTAGGFIYIATVSVVPELLESGDHNNLSKVAKMAQSLVHVLAICMGVGMMYIVSLVE
What is the function of this protein?
Zinc transporter which regulates intracellular zinc levels (PubMed:29879108).  Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function (PubMed:29879108).  Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm (PubMed:29879108).  The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable of fertilization (PubMed:29879108).
What are the official names of this protein?
Zinc transporter zipt-7.1, Histidine-rich membrane protein KE4 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Localizes to membranous organelles.
Protein: EX7L_SYNS3
Sequence: MSAESLPSYSVRELNNAIGVLLERGFAPRFVIQATVSRPQVKKGHLWLTLSDGEASITAVAWASKLKQLDFVPADGDGVTVIGKLNFWSARASLAVQVLDMRPSLTTVLRRFETVKAQLLEEGVIDPSRHRKLPAYPNRLAVLTSVPSSALADMLRTAQDRWPLSELLVVPIPVQGEVAPIICGVLNRLAETHHQLGLDAIVIARGGGSREDLMVFDDAEVCRKLATFPLPVVTGLGHEDDLTVADLVADHRAATPTAAMVTLMPSRESAQQTITQRRSRLSEYKRWRLEQANSRLRDRHLLLDALRPEVTLQRRRDQWQQRQQLLRALSPQRWLNRGFAMLNTTNGQPIQSINDISLNEQLQILLKDGVIQAVAKTIQANETSNSKTSP
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_LIMRD
Sequence: MAKISKIEAQKRKGRYNIYLDGKYAFPVAESVLIQFRLMKGTELDEKQIAAIATADQQAKAYSRMLDYLSYQMRTESDIVKKLKEIDTPEEFVESILKKLRGQQLIDDHAYAASYVRTMINTDLKGPGVIRQHLRQKGIGENDIDDALTQFTPEVQAELAKKLAEKLFRRYRNQPERRREQKVQQGLMTKGFSSSVYEMIKDEVVPQPDLEQENDLLAKEAAKQWRRVRCYQGYEREQHFKQAMYRKGFDLDDVQSWLDAQDFQ
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BXB8_BOMMO
Sequence: MKTSVIFVLIVLNLMWSGEAQEVARTYCGSHLADTLADLCFGVVKRGGAQYAPYFWQKAYLGSRGKRGVVDECCFRPCTLDVLASYCG
What is the function of this protein?
Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects.
What are the official names of this protein?
Bombyxin B-8, BBX-B8, 4K-prothoracicotropic hormone, 4K-PTTH.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SKIT9_MOUSE
Sequence: MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS
What is the function of this protein?
May act by engaging a cell surface molecule on immature T-cells in the embryonic thymus.
What are the official names of this protein?
Selection and upkeep of intraepithelial T-cells protein 9, Skint-9.
What is the protein family that this protein belongs to?
Belongs to the SKINT family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GYRA_FIBSS
Sequence: MSEEMVPGSQFKSLVEQDMQDCYLRYSMSVIVARALPDARDGFKPVHRRVMYSMHKLGVVPNKGTVKSARIVGDVIGKYHPHGDVAVYDTLARMAQDFSLRYPLVFGQGNFGSIDGDSPAAMRYTEAKMNNLGALMLEDLEKETVDMGPNYDESLEEPLVLPSALPNMIVNGTSGIAVGMATNMAPHNLREVGAAIHALAENPDLTGEDLMEYVKGPDFPTGAIVCGRSGIREAYLTGHGRVRVRARTEIETDAKGKPRIIVTEIPYMVNKAELCKKIADLVRDKRIDGITDIRDESSRDIRIVIELRRDAVGEVVLNNLFKYTQLQTTFSIYNLALVNNLPKLLTLKDLLQVYIDHRLDVITRATQFDLKKAAARLHIIEGLRIATQNIDEVVKIIRQSKTTEIAKQSLQDRFSLDEIQSQAIVDMRLAQLVGLNIEKLEAEYNELIATVADLKDILEKRERRVAIMLQKLDAVVDKYGDERRTTIGEAIDDSDDEDLIAEEEQVITLSKEGYIRRLPIDTFKAQNRGGKGIIGAGLKDEDNVEQIFTASTHSYLLVFTNKGRVYWTKVYRLPEGARNGKGRPIVNFVALTEGEKVQAIVPVRKFGGYFCLVFATKKGIINKMDLTLFSRPRKAGVNAISLDEDDELVKVQLVGMSAEEYEASKNASDDDSAEAVENAAEAQAAEAAIAEESESGDAEDFANRPIPKDLLMIATKNGQAVTFPISCFRAMGRGTHGVKGITLAEGDEVISLLWLKAGNKILTITEKGYGKRSEPGSYRVTRRGSKGVRNLNVTDKIGAAVFVESVADDYDLIITSKDGQVIRIKAADIRLTGRNAQGVKAITLRDGDVVKDATALPSVEDIEQDSADAKETFDKVKGVEVDDDSVVKDDAEKQEIGPTETEE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_NEIMA
Sequence: MKCPFCTHPDTRVADSRLMEERNAVRRRRHCPNCGKRFGTLETAELKMPAVIGPDKKRSPFNAQRLRNDLTAAARKSALTPEQIDETVRLTEHRLYTSGQRDIPSAALADMVLKELLRQDTEAAVRFAALHKRFDNPADFASWLAQAVKTGGKA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: BIOB_MYCTU
Sequence: MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: AMPA_LEGPC
Sequence: MNYGLTHTPSLTMSECLVLGVFSDLALPDFATAIDNEQKGLIKKLCQRVPEPGNTVWQTDVEGHSLLIIQCGKKEEFSANSLQKRVGEITEALIKQRFSSATVCLPRLNQESAEWQLEQMIVQIDNLRYQLLDFKTKHAKSHKLESVIFHLPGATEKSLEMAKAIVTGVEFCRDLANMPANICTPTYLGEQAISLSKQFDQISCQVMGPEEIKEMGMGALLAVAQGSDQPPRLIDIHYHGNKNSTPVILVGKGITFDSGGLSIKPANAMDEMKYDMSGAASVLGVIKACALLKLPINLIGIIASAENLISGSAVKSGDIVTTMSGQTVEIINTDAEGRLVLADALTYAERYNPDFVIDIATLTGAIIVALGNIATGYMTRDEQLAKSIERAANESQDKVWRMPLDEAYQDALESPLADMINAGFDRSAGSITAACFLSRFTEKYRWAHLDIAGTAWISGKKRNATGRPVPLLIQLLRHVANSR
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GVPA_CERSK
Sequence: MAIEKSVASASIAEVIDRILDKGVVIDAFVRVSLVGIELIAIEVRAVVASIETWLKYAEAVGLTVDPATT
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  GvpA type proteins form the essential core of the structure.
What are the official names of this protein?
Gas vesicle structural protein, GVP.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: SYA_PSE14
Sequence: MKSAEIREAFLGFFEEQGHTRVASSSLIPGNDPTLLFTNAGMNQFKDCFLGQEKRAYTRAVTSQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAITYAWTFLTSEKWLNLPKEKLWVTVYATDDEAYDIWTKEIGVPAERMVRIGDNKGAPYASDNFWTMGDTGPCGPCSEIFFDHGPEIWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERVSAVLQHVHSNYEIDLFQSLLAASAKAIGCSNDNQASLKVVADHIRSCGFLIADGVLPSNEGRGYVLRRIIRRACRHGNKLGAKGSFFYQIVAALVAEMGSAFPELVQQQSHIERVLKGEEEQFAKTLEQGLKILEQDLADLKGTVVPGEVVFKLYDTYGFPMDLTGDIARERNLTLDEAGFEREMDAQRVRARSASSFGMDYNSLVKVDVATQFTGYSATTGSASVVALYKEGQSVTHLNEGEEGVVILDTTPFYAESGGQIGDSGFLHAGDVRFDVSDTTKTGGAFLHHGVVASGSLSVGAQVETQVADEVRDATKLNHSATHLLHAALRQVLGEHVQQKGSLVDSQRLRFDFSHFEAIKPEQLRALEDIVNAEIRKNTEVMTEETDIDTAKKKGAMALFGEKYGDSVRVLSMGGEFSVELCGGIHASRTGDIALFKIVSEGGVAAGVRRIEAVTGAAALAWLNAAEDQLKEAATLVKGNRDNLLDKLTAVLERNRLLEKQLEQLQAKAASAAGDDLSAAALDVKGVKVLATRLDGQDGKALLALVDQLKNKLGRAVILLGSVHEDKVVLVAGVTKDLTGQLKAGDLMKQAAAAVGGKGGGRPDMAQGGGVDAGALDSALALAVPFVEQGI
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y479_STAAM
Sequence: MRGGGNMQQMMKQMQKMQKKMAQEQEKLKEERIVGTAGGGMVAVTVTGHKEVVDVEIKEEAVDPDDIEMLQDLVLAATNEAMNKADELTQERLGKHTQGLNIPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SAV0479.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ARLY1_ANAPL
Sequence: MASEGDKLMGGRFVGSTDPIMQMLSTSISTEQRLSEVDIQASIAYAKALEKAGILTKTELEKILSGLEKISEELSKGVIVVTQSDEDIQTANERRLKELIGDIAGKLHTGRSRNEQVVTDLKLFMKNSLSIISTHLLQLIKTLVERAAIEIDVILPGYTHLQKAQPIRWSQFLLSHAVALTRDSERLGEVKKRINVLPLGSGALAGNPLDIDREMLRSELEFASISLNSMDAISERDFVVEFLSVATLLLIHLSKMAEDLIIYSTSEFGFLTLSDAFSTGSSLMPQKKNPDSLELIRSKAGRVFGRLASILMVLKGLPSTYNKDLQEDKEAVIDVVDTLTAVLQVATGVISTLQISKENMEKALTPEMLATDLALYLVRKGMPFRQAHTASGKAVHLAETKGIAINNLTLEDLKSISPLFSSDVSQVFNFVNSVEQYTALGGTAKSSVTTQIEQLRELMKKQKEQA
What is the function of this protein?
Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles.  Despite possessing the necessary catalytic residues, this protein does not function as an enzymatically active argininosuccinate lyase.
What are the official names of this protein?
Delta-1 crystallin, Delta crystallin I.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
Protein: FMT_NITOC
Sequence: MAAPPHILFAGTPVFAAIILRRLLEAKYHIGAVYTQPDRPSGRGRRPTPSPVKDIAITHQLPLYQPATLKDKGSQAQLAALAPDLMVVAAYGLILPATVLQIPPLGCINVHASLLPRWRGAAPIQRALLAGDKVTGISIMQMDAGLDTGPVVHTARYPIHPKDTAATVHDQLAELGAEALLQCLPSLLEKKANIATLQDESQACYAPKIRKEEAWLDWSQPAVLLERQVRAFNPWPVAQTQIGGKTLRVWSAAALAQTANALPGTLLAVHKTGIDVATGNGTLRLLEVQLAGKRVMTVQDYLNAHTLTPGIVLVKNPGKAKSP
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SPA3C_MOUSE
Sequence: MAFIVALGLVITGICPGVLCFPDGTLERDTLFHKDKENGTQLDSLTLASINTDFAFSLYKKLALKNPDTNIVFSPLSISAALAIVSLGAKGNTLEEILEGLNFNLTETPEADIHQGFGHLLQRLSHPGEQVQISTGSALFVEKHLQILAEFQEKARALYQAEAFTADFQQPLEATKLINDYVSNQTQRKIKGLISDLDTDTLMVLVNYIYFKGKWKMPFNPRDTFESEFYLDVKRSVKVPMMKIKTLTTPYFRDEELSCTVVELKYKGNASALFILPDQGRMQQVEASLQPETLRKWKNSLRPRKMGELYLPKFSISTDYSLKNILPELGIKEIFSKQADLSGITGTKDLIVSQMVHKAVLDVAETGTEGVAATGVNFRILSRRTSLWFNRTFLMVISHTDVQTTLFIAKITHPKRA
What are the official names of this protein?
Serine protease inhibitor A3C, Serpin A3C, Kallikrein-binding protein, KBP.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMA_I87A3
Sequence: MKTTIVLILLTHWVYSQNPTSGNNTATLCLGHHAVANGTLVKTITDDQIEVTNATELVQSISIGKICNNSYRVLDGRNCTLIDAMLGDPHCDVFQYENWDLFIERSSAFSNCYPYDIPDYASLRSIVASSGTLEFTAEGFTWTGVTQNGRSGACKRGSADSFFSRLNWLTKSGNSYPTLNVTMPNNNNFDKLYIWGIHHPSSNNEQTKLYIQESGRVTVSTKRSQQTIIPNIGSRPWVRGQSGRISIYWTIVKPGDILMINSNGNLVAPRGYFKLRTGKSSVMRSDAPIDTCVSECITPNGSIPNDKPFQNVNKVTYGKCPKYIRQNTLKLATGMRNVPEKQIRGIFGAIAGFIENGWEGMVDGWYGFRYQNSEGTGQAGDLKSTQAAIDQINGKLNRVIERTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDAEMNKLFEKTRRQLRENAEDMGGGCFRIYHKCDNACIGSIRNGTYDHYIYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLICVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: SYK_CUPMC
Sequence: MTEPTRAQAATPTTEGLAVDENKIIAERREKLQALRQQGVAFPNDFQPTHQAGALHAQYGETDQATLEASPVEVSIAGRMMLKRVMGKASFATVQDGSGQIQFYITRDKVGEDVYAAFKHWDLGDIISARGELFRTNKGELSVQVRELRLLSKALRPLPDKFHGLADQETKYRQRYVDLIVSPETRSTFRARTQAISSIRRHMADAGFMEVETPMLHPIPGGAAAKPFITHHNALDMQMFMRIAPELYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTENLIRQAAIDARGSATVTYQGRELDLSKPFHRLTICGAIQKYAPEYTDAQLADADFLRAELKNKFKINTSAPQFLNAGLGTLQLVLFEETAEAQLWEPTYIVDYPVEVSPLARGSDTQPGITERFELFITGREIANGFSELNDPEDQAERFRKQVEQKDAGDEEAMYFDADYIRALEYGMPPTGGCGIGIDRLVMLLTDSPNIRDVILFPHLRRED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_CLOPS
Sequence: MNRVKSREYLLQLAYQMEITSETALETFNSFMENEDISKDDLDLAYIKSGLLGIEENKEKLDSLIESQLVKWKLNRISKVNLSILRISTYEILFAEDVPGKVSINEAIELCKKYSDNKSVSFINGVLDKVYKNIK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CH601_BRASB
Sequence: MAAKDVKFAGDARDRMLRGVDILANAVKVTLGPKGRNVVIEKSFGAPRITKDGVTVAKEIELEDKFENMGAQMLREVASKTNDLAGDGTTTATVLAQAIVREGAKAVAAGMNPMDLKRGIDTAVAAVIKDIEKRAKPVASSAEVAQVGTISANGDAAIGKMIAQAMQKVGNEGVITVEENKSLETEVDIVEGMKFDRGYLSPYFVTNAEKMTAELDDVYVLLHEKKLSGLQAMLPVLEAVVQSGRPLLIIAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLEDIAILTGGQLISDDLGMKLENVTIKMLGRAKKVVIDKENTTIVNGAGKKADIEARVGQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEIEVKEKKDRVEDALNATRAAVQEGIVPGGGVALLRAKKAVGRITNPNSDVQAGINIVLKALEAPVRQIAENAGVEGSLVVGKILEEKSETFGFDAQSEDYVDMVAKGIIDPAKVVRTALQDASSVAGLLVTTEAMVAELPKEAAPAMPAGGGMGGMGGMGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLCC_RICBR
Sequence: MLPPKTFFEKVKEIIWPIERKELKLFIPMALMMLCILFNFGALRSIKDSLVVPSMGAEIISFLKLWLVLPACVIFTILYVKLSNKFNFEYVFYIIVGSFLLFFLFFAYIIYPNQEAYHPNNEIINSLITSYPNFKWFIKIASKWSYGLMYIFAELWSAVVINLMFWQFANHIFDTNKAKRFYPVLGMVGNIGLILAGSVLVFFSGNKIIDPELLPNSFDASVNLTSQTTEMLQPIMSIIVAAGVISMLLFRIINKSILTDSINVLDSKKVKAKTKTKLSVLESIKLVINSKYIGRIALLIICYGLLINIVEGPWKAKVKELYPSTIDYVHFMGRFNILMGISCVTFMIIGSNILRRLGWFFSALLTPIMLSITGLMFFIFIIFIEEIGSCFGNFNLLYAAIIVGAIQNILSKSSKYSLFDSTKEMAYIPLSLELRTKGKAAVEVIGTKFGKSLGAFIQSLIFIIIPTATFDSIIIYLLVIFIVMISLWIWDVVKLNKEYTELCK
What is the function of this protein?
Provides the rickettsial cell with host ATP in exchange for rickettsial ADP.  This is an obligate exchange system.  This energy acquiring activity is an important component of rickettsial parasitism (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein 3, ADP/ATP translocase 3.
What is the protein family that this protein belongs to?
Belongs to the ADP/ATP translocase tlc family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.