PharMolix/UniProtQA huggingface dataset:
Protein: PETL_ANGEV
Sequence: MLTLLSYFGFLFAILTLTSVLFIGLNKIQLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PSBL_SYNSC
Sequence: MERNPNPNNLPVELNRTSLYLGLLFVFVTGVLMSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: HISX_BRUME
Sequence: MVTTLRQTDPDFEQKFAAFLSGKREVSEDVDRAVREIVDRVRREGDSALLDYSRRFDRIDLEKTGIAVTEAEIDAAFDAAPASTVEALKLARDRIEKHHARQLPKDDRYTDALGVELGSRWTAIKAVGLYVPGGTASYPSSVLMNAMPAKVAGVDRIVMVVPAPDGNLNPLVLVAARLAGVSEIYRVGGAQAIAALAYGTETIRPVAKIVGPGNAYVAAAKRIVFGTVGIDMIAGPSEVLIVADKDNNPDWIAADLLAQAEHDTAAQSILMTNDEAFAHAVEEAVERQLHTLARTETASASWRDFGAVILVKDFEDAIPLANRIAAEHLEIAVADAEAFVPRIRNAGSIFIGGYTPEVIGDYVGGCNHVLPTARSARFSSGLSVLDYMKRTSLLKLGSEQLRALGPAAIEIARAEGLDAHAQSVAIRLNL
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: DRE2_OSTTA
Sequence: MRVVVVDLDGVDGADLALERAYERAAALDDGATPATTYARDVRAPGAADGFIGDGATAAMASRTCARAWTALRAGGTVIARGGDAARDAAVLAGFADVVVDATRGVVRGTKPAWARGTAFSLKSRAVRVVTADAGWGADADVDDELIDESALLTELDVNSTAVKYDDCDVGAGKKACKNCTCGRAEAEAAEESANAKSEETFVSACGNCALGDAFRCAGCPYLGQPAFKDTDAVGTKVELDLGDDL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: CCA_LACDA
Sequence: MTNIRITEVFTQAMPVLEKLEEAGFEAYFVGGCVRDLLLERPIHDVDIATSAYPEEVKETFAKSIDTGIQHGTVTVLYGGSSYEITTFRTESGYQDFRRPDKVTFVQNLDEDLKRRDFTINALAMNRQGEIIDLFDGLGDLKRRVIKAVGVAEDRFHEDALRMMRAVRFMSQLSFSLEEKTRQAIINNHELLSKISVERIREEFVKLALGKDSRQAFKDFLATGLSEECPGLAGKKDQLSVLTDLKAGPDDEAVFWSLIAVLINLPADKISPFMRAWKNSNAMNQQVRQIVAAFDLLSRGEESDFDLFEIGQENLEAALKLAGLLGKPLSSQVLLDRYNRLPIKAAGELAIDGQWLIKEGIKPSPELGQLLRKALEGVVSGQVENSQAAIAEFLAI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: EFP_XANAC
Sequence: MATVGMNDVKNGMKILVNNEPAVITETEYVKPGKGQAFTRMKYRFIKSGRVVEMTMKATDDVEVADVVDTDMRYLYSDGEYWHFMDPDTFEQVQTDKAGMGGADKWLKGEEDCIVTLWNGTPIWVQPPNFVELKITETDPGVRGDTSGGGGKPATLETGAVVRVPLFVNQDEIIKVDTRSGEYSARVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRBD1_PONAB
Sequence: MSSLPRRAKVQVQGVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPQVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLNTVQTLKTAKTKRKCAAQPHAVRRTKKLKVDEETSKASYLEGESNSSETPSTSTVWGGTCKKEENDDEFTFGQSPLKKIKTETCPQGQPVKFPANANHIKEEVEMNWDIVQVLSERTNIEPWVCTNTIRLFNDDNTIPFIIRYRKELINNLDADSLREVQQTLEELRAVAKKVHSTIQKIKKEGKMSECLLKAMLNCKTFEELEHVSAPYKTGSKGTKAQRARQLGLEGAARALLEKPGELSLLSYIRPDVKGLSTLQDIEIGAQHILADMIAKDKGTLDFIRNLCQNRHVCIQSSLAKVSSKKVNEKDVDKFLLYQHFSCNIRNIHHHQILAINRGENLKVLTVKVNISDGVKDEFCRWCIQNRWRPRSFARPELMKILRNSLNDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLMGVDPGYKHGCKLAIISPTSQILHTDVVYLHCGQGFREAEKIKMLLLNFNCSTVVIGNGTACRETEAYFADLIMKNYFAPLDVVYCIVSEAGASIYSVSPEANKEMPGLDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIQTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTVANVLLKPNPLDQTCIHPESYDIAMRFLSSIGGTLYEIGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKRSIVCLKDLQVGTVLTGKVENATLFGIFVDIGVGKSGLIPIRNVTEAKLSKTKKRRSLGLGPGERVEVQVLNIDIPRSRITLDLIRVL
What are the official names of this protein?
S1 RNA-binding domain-containing protein 1.
Protein: MOC2B_SCLS1
Sequence: MASSKELIEENCYVALTHEHLDAKVMMDKVRSPKAGAIVLFAGTTRDNFGGKPVKELQYTSYEPRALQSMLSICKTILHKHSLTSIAMIHRLGVVPIGEESILITVSSPHRQAAWRAGEEALEECKEKVEVWKKEEFGGEEGGIWRANRDGAVGERVDEDEEKKKPDMGPHGPILRPSRPGERGHGPVVRNHQLGS
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Common component for nitrate reductase and xanthine dehydrogenase protein H, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_EHRCR
Sequence: MTLVPMVVEQTSRGERAYDIYSRLLKERIIFITGPIEDQMASLIVAQLIFLESENPEKEICMYINSPGGVVTAGLSIYDTMQYIKPKVSTLCLGQAASMGSLLLAAGEPGMRYALPNSRIMIHQPSGGFQGQATDIEIHAKEILDIKGRLNDIYVKHTGRDLSEVVANMERDNFMRAEKAKDFGIIDKVIEKRLDIGVE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_ANOGA
Sequence: MATWANLGLQDSSSPLMEQLNFFHDHTLLILTMITILVGYIMGMLSFNKFTNRFLLHGQTIEIIWTVLPAIILMFIAFPSLRLLYLMDEINTPSITLKSIGHQWYWSYEYSDFLNLEFDSYMVPTNELETNGFRLLDVDNRVVLPMNNQIRILVTATDVLHSWTVPSLGVKVDATPGRLNQLNFLINRPGLFFGQCSEICGANHSFMPIVIESIPMNYFIKWITSMTN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DYR_BPT4
Sequence: MIKLVFRYSPTKTVDGFNELAFGLGDGLPWGRVKKDLQNFKARTEGTIMIMGAKTFQSLPTLLPGRSHIVVCDLARDYPVTKDGDLAHFYITWEQYITYISGGEIQVSSPNAPFETMLDQNSKVSVIGGPALLYAALPYADEVVVSRIVKRHRVNSTVQLDASFLDDISKREMVETHWYKIDEVTTLTESVYK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: HEM6_PSEU2
Sequence: MSTRTEAVKAYLLDLQDRICTALEQEDGSAHFMEDAWTRPAGGGGRTRVIENGTVIEKGGVNFSHVFGSNLPPSASAHRPELAGRGFEALGVSLVIHPHNPHVPTSHANVRFFIAEKEGEEAVWWFGGGFDLTPYYGVEEDCVHWHRVAERACAPFGEDVYPRYKAWCDSYFHLKHRDEPRGIGGLFFDDVNQWDFDTSFAFIRAIGDAFINAYLPIVRRRKAAAYTVQQREFQEFRRGRYVEFNLVYDRGTLFGLQSGGRTESILMSLPPQVRWGYDWKAAPGSEEARLTEYFLTDRDWLAEN
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_CORDI
Sequence: MAAQPNAPESAWPVRELNSKVKSWIERLGHLWVEGQITQLNMKPSWKFSYITLRDPEAEASVQLTCATSLLHSLPSRLQDGDRVVVYGKPAFYEGRGSFSLWVTDIRPVGVGELLARIERLRQQLASEGLFDPALKKPLPFLPHTIGLITGRGSAAERDVLAVAHSRWPEVKFNVINTAVQGARAVPEIIEALQRLDADPSVDVIIIARGGGSVEDLLPFSEEALQRAVVAAHTPVVSAIGHEPDNPVLDNVADLRAATPTDAAKKVVPDVAAERQLIAELRSRSAAALRGWVHKERQQLAAVRSRPALADPVRAITLHREEIARSISSIRRDMRYMLSTERATVASLRQQVAALGPSATLARGYAVVQVVPRDGSAPEVVTTIGMSPPGSQLRIRVADGSITAAAMQTTPAD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROP_STAAR
Sequence: MDFNKENINMVDAKKAKKTVVATGIGNAMEWFDFGVYAYTTAYIGANFFSPVESADIRQMLTFAALAIAFLLRPIGGVVFGIIGDKYGRKVVLTSTIILMAFSTLTIGLLPSYDQIGLWAPILLLLARVLQGFSTGGEYAGAMTYVAESSPDKRRNSLGSGLEIGTLSGYIAASIMIALLTFFLTDEQMASFGWRIPFLLGLFLGLFGLYLRRKLEESPVFENDVATQPERDNINFLQIIRFYYKDIFVCFVAVVFFNVTNYMVTAYLPTYLEQVIKLDATTTSVLITCVMAIMIPLALMFGKLADKIGEKKVFLIGTGGLTLFSIIAFMLLHSQSFVVIVIGIFGLGFFLSTYEATMPGSLPTMFYSHIRYRTLSVTFNISVSIFGGTTPLVATWLVAKTGDPLAPAYYLTAISVIGFLVITFLHLSTAGKSLKGSYPNVDNEQDRAYYVEHPKEALWWVKERKD
What is the function of this protein?
May be a proton symporter involved in the uptake of osmolytes such as proline and glycine betaine.
What are the official names of this protein?
Putative proline/betaine transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTH_CHLPN
Sequence: MAKLIVAIGNPRHGYANTRHNAGFLLADRLVEELQGPPFKPLSKCHALMTLVESSSGPLVFIKPTTFVNLSGKAVVLAKKYFNVALSHILVLADDVNRSFGKLRLCFNGGSGGHNGLKSITASLGSNEYWQLRFGVGRPLEEGVELSNFVLGKFSEEENLQLGSIFVEASTLFTEWCSKF
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_MYCA9
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGSVQWVVRYQGGNNAGHTVVLPNGENFALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELAGLEERGIDTSGLILSADAHLLMPYHVAIDKVTERYLGSKKIGTTGRGIGPCYQDKVARIGIRVADVLDEESLRQKVHAALEFKNQVLVKIYNRKALDPDQVVDGVLEQAEGFKHRIADARLQLNQALERGETVLLEGSQGTLLDVDHGTYPFVTSSNPTAGGASVGSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLQTVPICVGYEVDGKRTNEMPMTQSEIYRATPVYEELPGWWEDISGARQFEDLPAKAQDYVLRLEELAGAPMSCIGVGPGRDQTIVRRDILSRS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_BUCAT
Sequence: MLQKKKYQKKSSKIIINKKAYYNYFIEKVFQSGLVLEGWEIKSIRSGKVNISESYIINDRNEMYLCNCLIEPLQMSSNRFSCDPTRKKKLLLHKNEIDFLSLKKKNTGYTMVSLSLFWKKSWCKLEFGLAKGKTAQDKRINLKKREWEQEKLKILKKTKETY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: TIM13_MOUSE
Sequence: MDSGFGSDFGGTGGGKLDPGAIMEQVKVQIAVANAQELLQRMTDKCFRKCIGKPGGSLDNSEQKCIAMCMDRYMDAWNTVSRAYNSRLQRERANM
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim13.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: KAX19_CENLM
Sequence: HFIDVKCTTSKECWPPCKAATGKAAGKCMNKKCKCQ
What is the function of this protein?
Potent selective inhibitor of Kv1/KCNA voltage-gated potassium channels.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 1.9, Hongotoxin-2, HgTX2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ALKL2_MOUSE
Sequence: MRVSGRPMLLALLLLLSTVGDRGRAQSRGPADRQTLLRLLVELVQELKKFHIGDSKRLQLLGESDFALGRREATDYGADQEEQRVEIVPRDLRMKDKFLKHLTGPLYFSPKCSKHFHRLYHNTRDCTIPAYYKRCARLLTRLAVSPMCMER
What is the function of this protein?
Cytokine that acts as a physiological ligand for receptor tyrosine kinases LTK and ALK, leading to their activation.  Cytokine-binding is sufficient to activate LTK.  In contrast, ALKAL2-driven activation of ALK is coupled with heparin-binding to ALK.  Stimulation of ALK signaling is involved in neural development and regulation of energy expenditure.
What are the official names of this protein?
ALK and LTK ligand 2.
What is the protein family that this protein belongs to?
Belongs to the ALKAL family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Following interaction with receptor tyrosine kinase ALK, associates with the cell membrane, membrane-binding is required to activate ALK.
Protein: MURG_CLAMS
Sequence: MTVYLLAGGGTAGHVNPLLAVADELRAREPGSTILVLGTREGLESRLVPARGYELLTIARLPFPRRPNGAAVRFAPAFTRAVGQIRRMIAERGVDVVVGFGGYAAAPAYLAARRSGVPVVVHEANASPGLANRLGARVATAVGITFPGTALGPRAEVVGMPLRREIATLDRDAVRDAARAELGLDADRPTLLVTGGSTGARSLNRTVVQVAERITATGAQILHIVGGAQEFTDPGVERYHVVGYSDRMELAIAAADLVVSRAGAGALSELTAVGIPAVYVPYPVGNGEQAVNVRGVVAAGGGIVVADADFTPDWVLAHVVPLLSDPAALARMSEAAASVGTRDGAARMADLVRDAVASRPSRPAVRR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PIANP_RAT
Sequence: MWPAQLLSQLLPLWPLLLLPLSLPAQGSSHRSPPAPARPPCVRGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSVNPGFLPLDYGFAAPHGLATPHPNSDSMRDDGDGLILGETPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPTPTPDHEEPRGGPRPGMPQPKGAPAFQLNR
What is the function of this protein?
Acts as a ligand for PILRA in neuronal tissues, where it may be involved in immune regulation.
What are the official names of this protein?
PILR alpha-associated neural protein, PILR-associating neural protein, Paired immunoglobin-like type 2 receptor-associating neural protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SYE1_RUEST
Sequence: MSQPVVTRFAPSPTGFLHIGGARTALFNWLFARGRGGKFLLRIEDTDRARSTPEATAAILQGMAWLGLDHDGEVVSQFEGAERHAEVAHQLLAEGKAYKCFSTQEEIAAFREAAKAEGKSTLFHSPWRDTPESEHPDAPFAIRIKAPKDGETVIRDQVQGDVTIKNAQLDDMILLRSDGTPVYMLAVVVDDHDMGVTHVIRGDDHLMNAARQMMIYEAMGWDVPVYAHIPLIHGSDGKKLSKRHGALGAQEYQAMGYPAAGMRNYLARLGWSHGDDEFFTDEQAKDWFDLDGIGKSPARFDTKKLENLCGQHIAIADDAALRQEIEAYLDAAGQPALNDVQSQGLERAMYCLKDRAKTFPELLEKAHFVLTSRPLERDAKAEKALDPVSIGILNELTPHLQNASWSRDELEAALNEFAAAKDTKFGKLAGPLRAVLAGRAVTPSVFDMMICLGREETLARLKDVTG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPT1_TRIV2
Sequence: MATINDNYLKLKAGYLFPEIARRVNAFAEANPDAKIIRLGIGDVTEPLPEACRTAMIQAVEEMGDRSSFKGYGPEQGYAWLREKIATQDFQARGADVDASEIFISDGSKCDTGNILDIFGDNNIIAVTDPVYPVYVDTNVMAGHTGVANDKGEFEGLVYLPVTAENNFTAEIPSQKVDLIYLCFPNNPTGATATKEHLQAWVDYAKAHNSIIFFDAAYESYITDPSLPHSIYEIEGAREVAIEFRSFSKNAGFTGTRCALTVVPKTLKAKAADGSDVELWKLWNRRQSTKFNGVSYIVQRGAEAVYSEAGQAQVKALVSFYLDNAKIIREKLTAAGLSVYGGVNAPYVWVKTPNGLSSWDFFDKLLQTVNVVGTPGSGFGAAGEGYFRISAFNSRENVEEAMQRITEKFKL
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase 1, DAP-AT 1, DAP-aminotransferase 1, LL-DAP-aminotransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: URED_VIBPH
Sequence: MFDMSSSSSGWVAEIYLRYQLKRGITRLIERKQVGPLMVQRPFYPEHGSSHTYLLHPPGGVVAGDLLSINVVVEEGAHSLITTPGATKFYRSIGEVARQAQNLRVEEDAFLEWLPLENIFFPSAAAILETNISLKVSSRFIGWDMLCFGRPMLNETFESGNVIGQTKIFVDDKLILADSLCVDSTKFKAAGMREFPMLGAMYIYPASEALKELVHRSIQDYLMQTKESLEIGLTDVDGLLTVRALGHQTEEIMGCLVLIWKTCRKLWLGYVPDIPRIWAT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.