PharMolix/UniProtQA huggingface dataset:
Protein: GSPI_PECCC
Sequence: MRRQKGMTLVEVLVALSVFALAGIAVLQTTARQASSLSRLEEKTFAGWVAENQQVQLRLEQRWPEASWVRGETQFAGLRWHWRWQGVETGDPQTKALDVEVRRNKDAFAADASLRTYVVKQ
What is the function of this protein?
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
What are the official names of this protein?
Type II secretion system protein I, T2SS minor pseudopilin I, General secretion pathway protein I, Pectic enzymes secretion protein OutI.
What is the protein family that this protein belongs to?
Belongs to the GSP I family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HMGC2_MOUSE
Sequence: MGNLPSAAKHCLNYQQLLREHLWSGDSVAGALDAAQEASQLPGLPEYVKIVEVGPRDGLQNEKVIVPTDIKIELINQLSQTGLSVIEVTSFVSSRWVPQMADHAEVMRGIRQYPGVRYPVLTPNLQGFQHAVAAGATEIAVFGAASESFSKKNINCSIEESMGRFQEVISSARHMDIPVRGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKMMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGMGLNTGVDLYKVMEAGEFICKAVNKTTNSKVAQASFNARLE
What is the function of this protein?
Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic, 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA lyase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: RL33_MYCLB
Sequence: MASSTDVRPKITMACEVCKHRNYITKKNRRNDPDRMELKKFCRNCGKHQSHRETR
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS16_OENOB
Sequence: MSVKIRLHLMGTKKRPFYRIVVADSRARRDGRFIEEVGYYNPITKPAEIKLNDDQIFNWLMKGAQPTNTVRNFLSDAGLMKKLHEAKLAAKKESKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL13_BACCR
Sequence: MRTTFMAKANEVERKWYVVDAEGQTLGRLASEVASILRGKNKPTFTPHVDTGDHVIIINAEKIHLTGNKLNDKIYYRHTNHPGGLKQRTALEMRTNYPVQMLELAIKGMLPKGRLGRQVSKKLNVYAGAEHPHQAQKPEVYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ANR10_MOUSE
Sequence: MSAGAGAAVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKLECLMQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECITALVGSGAHTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCHNGTLSGGHESILPTHVSLGTNRKRCLEDSESLGVKKARTRVPSLDHAMPLANGEAEDDADRMHVDRECAAVSDMKNSSSVLNTLTNGSVVNGHLDFPCANQLNGMESRSHPCLTGSNGVSNGQPLSSGQASVSANGTEEPEKTMGINPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHTSCVRVEQRYDSAVLGAMQLHHGS
What are the official names of this protein?
Ankyrin repeat domain-containing protein 10.
Protein: RUAP_SOYBN
Sequence: MSTKFKVFREFTSDDSFLNQVIPENITEFQVTLSLARDYDGNNSTNGKFIPYWDTEKVTPEVIKKFKKKYEPTALRVKVLVSIGNKNKQFPFTIGSDSNSEAWVSEATASLKSIIKTYNLDGIDVSYEDIAANEADFVNSVGGLVRNLKQNKLITVASFATSADAANNKFYNLLYAEYATFFDTVVFLSWVGFTPSRANPVASLEEKILAVANEYKAVKAFLVAYSTVAEDWANFSPPIFFITLHGLLGNSAVKGASIKVISDATASFPAKWIPEILLLAASK
What are the official names of this protein?
RuBisCO-associated protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
Protein: T2R50_PANTR
Sequence: MITFLYIFFSILIMVLFVLGNFANGFIALVNFIDWVKRKKISSADQILTALAVSRIGLLWTLLLNWYLTVLNPAFYSVELRITSYNAWVVTNHFSMWLAASLSIFYLLKIANFSNLIFLHLKRRVRSVILVILLGTLIFLVCHLLVANMDESMWAEEYEGNITGKMKLRNTVHLSYLTVTTLWSFIPFTLSLISFLMLICSLCKHLKKMQLHGEGSQDLSTKVHIKALQTLISFLLLCAIFFLFLIISVWSPRRLRNDPVVMVSKAVGNIYLAFDSFILIWRTKKLKHTFLLILCQIRC
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 50, T2R50.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MED26_BOVIN
Sequence: MTAAPPSPQQIRDRLLQAIDPQSNIRNMVAVQEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEAALRGLAGAPGSANGGAHNCRPEAGAAGPPKSVHDLKYRNDMPRLCGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDSLVPNSSPLPTNGISGSPESFPSPLDSSGHVGPEGNRLEHGENDKHSGKIPVNAVRPHTSSPGLGKPPGPCLQTKAVVLQQLDKVDETPGPPHPKGPPRCSLGSRNSRHEGSFARQRSPYTYKGSLPSPSPRPQSLDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLAGLGCKAGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPRTELDKPEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKPHVLVPHGPPTDFPGLSREVTRDDLDKIQAHQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 26, Cofactor required for Sp1 transcriptional activation subunit 7, CRSP complex subunit 7, Mediator complex subunit 26.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 26 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM4_SCHPO
Sequence: MKTALLLKTKSQPFDPYVEAFEKYGRDTAFIPVLRHKRVHEEQLRDKLKNVRKTYCGLIVTSQRVSETLDEALKQEDETERQKILMETPIFTVGPATDDSIRRLGFQQTHGKDCGRGEVLADLIEEWYTTTKQHKPLLFLVGEKHRDIIQRKLGDDRVDSLIVYATQELENTETQIKDTIRKHPTIDWIVAFSPTSICSLLNTFELKIATIGPTTGDYLKKLGTQPNVVSPAPNPESLASSIVAFDEENSS
What is the function of this protein?
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
What are the official names of this protein?
Uroporphyrinogen-III synthase, UROIIIS, UROS, Hydroxymethylbilane hydrolyase [cyclizing], Uroporphyrinogen-III cosynthase.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen-III synthase family.
Protein: HOA_PECAS
Sequence: MAKKILLCDPTLRDGNHAVRHQLTRESFAAYCQAAEAANVPVVEVGHGNGLGASSMLVGECLLSDEDIFTISREHLHKSRMAIHLIPGFCTIKKDLTRALELGVDLFRVASHCTEADITDRHIHFVRNSGKEAWGILMMSHMTSPAVLLEEARKMESYGAEAIVIMDSAGAYFPDDVKERISTLVNGLTVPVGFHGHNNLGMSVINSVVAVQEGATIIDGTIRGFGAGAGNTQLEVLVAVFERLGYETGIDLYKILDAADIAEKGFNPVAPSISPLSIVSGLAGVFSGFAKPVAKAAKDYNVDPRDIFFGLGERKAVAGQESLIYEVARDLAKRNENSVEKGQ
What is the function of this protein?
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde.  Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: GPN2_MOUSE
Sequence: MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANDGLPYECAVDVGELVGLGDVMDALRLGPNGGLLYCMEYLEANLDWLRAKLEPLRGHYFLFDCPGQVELCTHHTALRSIFSQMAQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHINLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLEHLASDPFFRRYRQLNEKLVQLVEDYSLVSFIPLNIQDKDSIQRVLQAVDKANGYCFGVQEQRSLEAMMSAAMGADFHFSSTLGIQEKYLAPSEQTAEQEAMQL
What is the function of this protein?
Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 2, ATP-binding domain 1 family member B.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: RS18_SALCH
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CYSH_ESCF3
Sequence: MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_FRAT1
Sequence: MEVQAKLKFARISAQKCRLVADQIRGLPVEQAINLLTFSNKKAAVLIKGVLNSAVANAEHNDGMDVDSLVVSTIFVDEGPTMKRFEARAKGRGNRILKRTSHITVKVAEKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SSPH_ALKMQ
Sequence: MDKTRAQEIISSPNMISVTYNGKEIYIENVNENTQTANIHLLNKPDKKQEVPLNNLVEH
What are the official names of this protein?
Small, acid-soluble spore protein H, SASP H.
What is the protein family that this protein belongs to?
Belongs to the SspH family.
What are the subcellular locations of this protein?
Spore core.
Protein: SCAM2_HUMAN
Sequence: MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSETNAATTVPVTQLPGSSQPAVLQPSVEPTQPTPQAVVSAAQAGLLRQQEELDRKAAELERKERELQNTVANLHVRQNNWPPLPSWCPVKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFSGNSSKGVDFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIPGLGDSGWIAALSTLDNHSLAISVIMMVVAGFFTLCAVLSVFLLQRVHSLYRRTGASFQQAQEEFSQGIFSSRTFHRAASSAAQGAFQGN
What is the function of this protein?
Functions in post-Golgi recycling pathways.  Acts as a recycling carrier to the cell surface.
What are the official names of this protein?
Secretory carrier-associated membrane protein 2, Secretory carrier membrane protein 2.
What is the protein family that this protein belongs to?
Belongs to the SCAMP family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein.
Protein: TX90A_PHORI
Sequence: ACIPRGEICTDDCECCGCDNECYCPIGSSLGIFKCSCAHANKYFCNRKKEKCKKA
What is the function of this protein?
Antagonist of L-type calcium channels (Cav1/CACNA1).  In vivo, causes paralysis in posterior limbs, and gradual decrease in movement and aggression during 24 hours after intracerebroventricular injection in mice at dose levels of 3 ug per mouse.
What are the official names of this protein?
Omega-ctenitoxin-Pr2a, Omega-CNTX-Pr2a, Neurotoxin PRTx23C2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 09 (Tx3-6) family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEA_BRUSU
Sequence: MRVDLFDFDLPEERIALRPVEPRDHAKLLHVRPGEPFEDRHVYDLPDLLQPGDALVFNDTKVIPAQLEGMRERTGNISQVSATLHMRVGPDRWKAFLRPAKRVKEGDRIRFGHSGTSCFLGTLDATVAEKGDSGEALLVFDLSGAVLDEAIAAVGHIPLPPYIASKRPEDERDRKDYQTVYAREEGAVAAPTAGLHFTPDLLEKIKARGIEEHFVTLHVGAGTFLPVKADDTGDHKMHAEIGHVSQRTASALNAVHERGGRIICVGTTSLRLIESATGEDGVVRPWSGATDIFITPGYRFRAVDLLMTNFHLPRSTLFMLVSAFSGLDTMHAAYNYAIADGYRFYSYGDASLLERIDHDRHSA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF2_SYNE7
Sequence: MNAWMILAAEAVQEAEGGLFDLDATLPLMAVQILVLVFLLNAVFYKPFGKVLDDRDQFVRGGRQDAKARLAEVKALTAQYEQELAATRKQSQALIAEAQTEAGRIAAQQLAEAQREAQAQREQAQQEIDQQKAVALQALDQQVDALSHQILDKLLARA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', ATP synthase F(0) sector subunit b', ATPase subunit II, F-type ATPase subunit b', F-ATPase subunit b'.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ODPA_RICBR
Sequence: MDIKLGKYKPVKEEYIKSFKDMLLLRRFEEKCGQLYGMGEIGGFCHLYIGQEAVISAVDMVKQKEDSMVTSYRDHAHIILAGTEPKYVLAELMGRATGCSKGKGGSMHLFDVPNKFYGGHGIVGAQVPIGTGLAFAEKYNGTNNICFTFLGDGAVNQGQVYEAFNMAALWGLPVVYIIENNEYSMGTSVARSTFMRDLYKKGESFGIKGFQLNGMDFEEMYDGVKQAAEYVRENSMPLILEVKTYRYRGHSMSDPAKYRSKEEVETYKERDPITEIRKIILENNYASEADLKEIEQSVKEIVKEAVEFSENSPLPNEEELYTQIYV
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha.
Protein: VGCR_ELHVK
Sequence: MDVLNLFNETIKVGAFNATQLVEAYVISIFSLTTFVGLAITLYLGIAYLYKKPADQVVGLVCCDVLIVNAVCLITLPLWVYQAATKKWFGGEFMCKFAGMFYTMNVYMSVWSCVIVTFDRWYCMMCKNLQAVTVLGRTIRTNQVVTILTLLVTFIGLFSLTETSIVDKKCYLYSGDSLLSFVNAALGYTVPWLAIAIMIVHIILRTSRLDYDPKWLNTNILMWMMFTLLVTQGPYYSLSAYMGNFKSFVEKNMTHHSNKVTASYFHGDASHSIQVAMLVCTHALAITRMFSVPLILSTLAGYEPLYVWKRITRCCCMRVEYENLEDESQSKLLRGEENPNYDYSPKSVRIKPLKSPGGGDNSSLKDEGYDEESQNGFSIG
What are the official names of this protein?
G-protein coupled receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: PHAS_MYCTU
Sequence: MGLGSAASGTGADRGAWTLAEPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGRTVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSATGVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKVVLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTNVHAVVEQAPQTEAQPHAASTPPTGTPALFTLSASSADALRQTAQRLTDWIQQHADSLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWLFSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPTIFAMQVALAATMAAYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIAGSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVLARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADNLRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPLGLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVHPLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGEQSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSGECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEVALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGSGLLVPLGVRRVRAYAPVRTARYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEWHQRELPEMDPSGAGKWLLISDCAASDVTATRLADAFREHSAACTTMRWPLHDDQLAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVPRMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLLATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAFHRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHKVGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAGDTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQIRRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFYAVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKLVLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQPTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDATLANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWLDAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEALLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSSNGSGTSKFRVELNELPRDEWPARLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSATVRGLADHLYEQLAPDDAPAAALSSQ
What is the function of this protein?
Involved in sulfolipid-1 biosynthesis (PubMed:11278910, PubMed:12724526).  Catalyzes the synthesis of the hepta- and octamethyl phthioceranic and hydroxyphthioceranic acids, the methyl-branched acyl constituents of sulfolipids (PubMed:11278910).
What are the official names of this protein?
Phthioceranic/hydroxyphthioceranic acid synthase, Polyketide synthase pks2.
Protein: MUTS2_CALBD
Sequence: MNQKTLKALEYDKIVEILKNMAKSTPAKEYFENLIPSTNVADIENELNKVDESYRYVLKYGNLPTLEFENILPSLKKSKLGATLNPHEILQIGKVLKLSYEMRTYLSFTQDFSFLESMKKRLVNLKEVISRIDQTFLTPDEILDTASSKLKEIRDKIRKLENKIRDELNSMIRDPKIQRFLQEPIITIRGEKLLLPVKAEFRNEVKGIVHDQSATGATLFVEPFVCVEISNQIKILKNQEKEEIERILQEISSLIASYCEVIETSFYALVELDIVFTKAIWAKEMNASKPIINASGIINLKKARHPLIQKDKVVPIDIHLGKDFDVLIITGPNTGGKTVTLKTVGLFCLLCQSGIFIPADEGSELCIFQKIFADIGDDQSIVQSLSTFSAHMKNIIEITKNADDKTLVLLDEIGAGTDPEEGAALAKAILKYLSEKGSKVIATTHYGELKIFAQQEDRFENASCEFDVKTLKPTYRLLIGIPGRSNALVISSNLGLDKGIVEMARGYLSQKTIDLDRIINEMEQKRKEAEENLELAQKLKHEAQALKAAYEEEKKRFETERERIRKKAINEAKEIVESSQYEIENLFKDLRKLAENLKEKEVLKELEEKKREYERLIQSISQQVKQEAESKTKKTIQNLRLGQKVYVRSFDAEGFVESLPDSKGNLTVQIGIMKINVNLSDIEEVEGQDSKIYQIASRNVIIKEKNIDMSIDVRGKTSDDAILEVDKYLDDAYTAGLKQVTIIHGKGTGVLRQAIRNFLRRHPHVKSFRDGTYGEGEQGVTVVELKD
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: NOC4_ARATH
Sequence: MASILSKKQKKNEKYTLKELKSLGHDLLTSRSHINNLPLLLTFVSPESPPQFVVESLLSLQSFFTPLLSQLPPTSSSPSSTKTEDPEVVFKAWLRSKFDEFVKLLLDVLVSQQSEDSLRGIVLGTLMEFVKLLNAGRFHSSIYHRLLDAIIHSEVDIEIFLDILTSKYFKYIDVRYFTYISMEKFVKTLEASVSADRTVIENNEAESDSKESLELSVRKIYQVLSQIPPPEKQAEKSQHEMWSGSDESISEKPTDKKKKTEKGDSTLLSPATISKRMKLKFTKAWISFLRLPLPIDVYKEVLASIHLTVIPHLSNPTMLCDFLTKSYDIGGVVSVMALSSLFILMTQHGLEYPFFYEKLYALLVPSVFVAKHRAKFLQLLDACLKSSMLPAYLAASFTKKLSRLSLSIPPAGSLVITALIYNLLRRNPTINHLVQEIVENADEANTEAGEHNESQPKTIKKRKLGIDYFNNQESDPKKSGALKSSLWEIDTLRHHYCPPVSRFISSLETNLTIRSKTTEMKIEDFCSGSYATIFGDEIRRRVKQVPLAFYKTVPTSLFADSDFPGWTFTIPQEEGTC
What is the function of this protein?
Essential protein required during embryogenesis (PubMed:15266054, PubMed:23382868).  Involved in nucleolar processing of ribosomal RNA (rRNA) 40S and 90S ribosomal subunits and ribosome assembly; early in ribosome biogenesis, especially required during the maturation of 5. 8S rRNA (PubMed:23382868).  Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
What are the official names of this protein?
Protein NUCLEOLAR COMPLEX ASSOCIATED 4, AtNoc4, Protein EMBRYO DEFECTIVE 2762.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Nucleus, nucleolus.
Protein: MPI_MOUSE
Sequence: MASPRVFPLSCVVQQYAWGKVGSKSEVACLLASSDPLAQISEDKPYAELWMGTHPRGDAKILDNRISQKTLGQWIAENPDCLGSKVKNTFNGKLPFLFKVLSVDTALSIQAHPNKELAEKLHLQAPEHYPDANHKPEMAIALTSFQGLCGFRPVEEIVTFMKKVPEFQLLIGDDATAQLKESVGGDTEAMASALRNCFSHLMKSEKKVVVEQLNLLVKRISQQVFDGNNMEDIYGKLLLQLHQQHPGDIGCFAIYFLNLLTLKPGEAMFLDANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLNYTPSPSNNRLFAPAQSQDDPYLSIYDPPVPDFTVMKMEVPSSVTEYKVSTLDSASILLMVQGTVTAIIPSAHAEIPLYRGGVLFIAANESVLLKITVPKDLLIFRACCLL
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
What are the official names of this protein?
Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYW_RICPR
Sequence: MKKTVLSGVQTTGALHLGNYLGSIRNWIKMQEEYNCFFFLADLHAITIDIKTSELNDAIMEVLAIYLAAGLNPDKVTIFAQSMVKEHVELSWLLNCVTPLGWLKRMTQFKDKAGSAQCKACLGLFAYPILMAADILIYKADIVPVGEDQKQHLELTRDIAEVINRRFDKEILKVPDILISETGTRIMSLRNGLKKMSKSDISDFSRINLKDSNDLIHQKIKKAKTDHLSFISYNKKTRPEISNLLDIYKSFSKESIEKIIDNYQNQGFAKFKEDLAEIIITNLQPIRNKCLELMNDKEYLLKILHKGAQKARIRASETVNEVKKQFGFII
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODF_BORPE
Sequence: MAHTLPPLPYALDALAPRISKETLEFHYGKHHQTYVTNLNNLIPGTEFENLSLEEIVKKSSGGVFNNAAQVWNHTFYWNSLSPNGGGEPSGALADAIKAKWGSVDAFKEAFNKSAAGNFGSGWTWLVKKADGTLDIVNTSNAATPLTTADKALLTCDVWEHAYYIDYRNARPKYLENFWALVNWEFAAKNFA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: AADH1_MALDO
Sequence: MAIQIPSRLLFIDGEWREPVLKKRIPIINPATEEIIGHIPAATAEDVELAVEAARRALSRNKGRDWASAPGAVRAKYLRAIAAKIGERKPEIAKLEAIDCGKPLDEAAWDIDDVSGCFEYYAELAEGLDAQQKAPISLPMEQFKSHVLKEPIGVVGLITPWNYPLLMATWKVAPALAAGCAAILKPSELASVTCLELADVCREVGLPPGVLNILTGLGHEAGAPLVSHPHVDKIAFTGSTMTGSKIMTAAAQLVKPVSLELGGKSPIVVFDDVDIDKAAEWTAFGCFWTNGQICSATSRLILHENIATEFLDRLLKWCKNIKIADPLEEGCRLGPVVSGGQYEKILKSIETAKSEGARVLSGGDRPEHLKKGFFIEPTIITDVTTSMQIWREEVFGPVLCVKTFSSEDEALELANDTHYGLGAAVISKDLERCDRFSKGLQAGIVWINCSQPCFCQAPWGGNKRSGFGRELGKWGLDNYLTVKQVTEYVSDDPWGWYTSPSKL
What is the function of this protein?
Dehydrogenase that catalyzes the oxidation of several aminoaldehydes (PubMed:26296314).  Metabolizes and detoxifies aldehyde products of polyamine degradation to non-toxic amino acids (Probable).  Catalyzes the oxidation of 4-aminobutanal and 3-aminopropanal to 4-aminobutanoate and beta-alanine, respectively (PubMed:26296314).
What are the official names of this protein?
Aminoaldehyde dehydrogenase 1, peroxisomal, MdAMADH1, Aminobutyraldehyde dehydrogenase AMADH1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.