PharMolix/UniProtQA huggingface dataset:
Protein: PSB1_RHOER
Sequence: MTADRPALRTGDRDTRLSFGSNLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.  The R. erythropolis proteasomes are able to cleave oligopeptides after Tyr, Phe and Leu, very poorly after Arg but not after Glu.  Thus, displays chymotrypsin-like activity, low trypsin-like activity but no caspase-like activity.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PrcB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSDMA_HUMAN
Sequence: MTMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLLDVLEPGSSPSDPTDTGNFGFKNMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLEVQTLSVAPKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEACFSLPFFAPLGLQGSINHKEAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEALPKDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTKAS
What is the function of this protein?
Pore-forming protein that causes membrane permeabilization and pyroptosis (PubMed:17471240, PubMed:27281216, PubMed:35110732, PubMed:35545676).  Released upon cleavage by S. pyogenes effector protein SpeB, and binds to membrane inner leaflet lipids (PubMed:27281216, PubMed:35110732, PubMed:35545676).  Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis (PubMed:27281216, PubMed:35110732, PubMed:35545676).  Pyroptosis triggers the elimination of the infected skin cell, depriving the pathogen of its protective niche, while inducing an inflammatory response (PubMed:35110732, PubMed:35545676).  This ultimately prevents bacterial penetration of the epithelial barrier and a subsequent systemic dissemination of the pathogen (PubMed:35110732, PubMed:35545676).  Binds to cardiolipin and other acidic phospholipids, such as phosphatidylserine, which mediate its targeting to the inner leaflet membrane (PubMed:27281216, PubMed:35110732).
What are the official names of this protein?
Gasdermin-A, Gasdermin-1.
What is the protein family that this protein belongs to?
Belongs to the gasdermin family.
What are the subcellular locations of this protein?
[Gasdermin-A]: Cytoplasm, perinuclear region. Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Gasdermin-A, N-terminal]: Cell membrane; Multi-pass membrane protein.
Protein: RLA12_ARATH
Sequence: MSTVGELACSYAVMILEDEGIAITSDKIATLVKAAGVEIESYWPMLFAKMAEKRNVTDLIMNVGAGGGGGGAPVSAAAPAAAGGAAAAAPAKEEKKDEPAEESDGDLGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P1-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: RLIP_DROME
Sequence: MDFDSPEEKEFPGLYASEAADAKSRKSKEESDFSEDHDHSKKDLLIGRRKDKKEKGKDRGYAALEGESSPEEELDTKSPSKSKKSKTFKFTSSKSKEKREKSRDKSEKDSKHAEEEPSVSHKVKEKERDKEKDRDEPKKKDKEEKRKEKDKKADKKDKKDKKSKQLSQQQDDVSAAEEVLALGYPVFGVSVSLATERSRCHDGVDIPLVVRDCIDFLQDHLKCEQIYKIEPIKTRLMHFKRLYNNREHDSAVDELNLPTACSLLKLFLRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQQERHNKLNAQSLAMLLSPTLQMSHRLMVALLCHCNNLFADVQLIKYVPPLTSTSPKLPDTPEDIQTELRKQDSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLKRKLRTFEKKQEKTAEEVDNSSSAPPAVASEDTTDSKPAGTPAVSTNNSISQEEPKTDTLTPKDAPNDFTIDPSTGFILLPKSNPHRENLLRLQIEYDELMEWQNELKARIVAERNEVYRLKQLYEQQSINSQMASLASGSQAPPESDYERIIEHYTRENALLEHKKNMLGMELKEERRACIALQVELRLQQF
What is the function of this protein?
Participates in receptor endocytosis during interphase, is also involved in mitotic processes when endocytosis is switched off.
What are the official names of this protein?
RalA-binding protein 1, RalBP1, Ral-interacting protein 1.
Protein: RPOS_VIBCH
Sequence: MSVSNTVTKVEEFDFEDEALEVLETDAELTSDEELVAVEGASEDVREEFDASAKSLDATQMYLSEIGFSPLLTAEEEVLYARRALRGDEAARKRMIESNLRLVVKISRRYSNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERALMNQTRTIRLPIHVVKELNIYLRTARELSQRLDHEPTPEEIALELDRPVDDVTKMLRLNERISSVDTPIGGDGDKALLDILPDSHNADPEFSTQDDDIRESLLNWLDELNPKQKEVLARRFGLLGYEPSTLEEVGREINLTRERVRQIQVEGLRRLREILVKQGLNMEALFNVEYDN
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response (By similarity).  May be required for the persistence of V. cholerae in aquatic habitats.
What are the official names of this protein?
RNA polymerase sigma factor RpoS, Sigma S, Sigma-38.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_DEHMB
Sequence: MADVRPENNESFESMLKRFNRKVQQDGILSEARRRTRFERPPTRRKRKDAAKRRLAIKAARKAT
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: TL17_ARATH
Sequence: MASLPVQFTRNQISSPFFSVNLRREPRSLVTVHCSAGENRENGEGVKKSLFPLKELGSIACAALCACTLTIASPVIAANQRLPPLSTEPDRCEKAFVGNTIGQANGVYDKPLDLRFCDYTNDQTNLKGKTLSAALMVGAKFDGADMTEVVMSKAYAVEASFKGVNFTNAVIDRVNFGKSNLKGAVFRNTVLSGSTFEEANLEDVVFEDTIIGYIDLQKICRNESINEEGRLVLGCR
What are the official names of this protein?
Thylakoid lumenal 17.4 kDa protein, chloroplastic, P17.4.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: BAZ2A_XENLA
Sequence: METQNHLSCTGQTPLTNASGLKLLPQSVEPVYTNSTLTSFSQHGKVLNYDLPVNGLISPSLSNNAHGTLLSNEHITHNSASNNFDYLWKKPKSSVHKDSHVSNQFLVNGSTCPITNGPSIKRSPQETLGNCTSNQTASFNVSSHSVCSPNEANVKMVTAANGAHYGFYEASLPVSVSASNMQSVSGDNLVKERTVEENEAGATEERNHTPELAEALEPSDTQTDLNICEYKESVLDPVIQSTPNPLLPPDVSNLDDPSQLPSQLGDSHLLNEDSLEPFGADLIQDPISSTMYDLEELEVGSTKQKDPQLDTSSLDCPTYSLSAAFPLVAEDTNDSSVLFNASSASPVLGDSVMQESASEMGEDPEGSKAEEPVSGPENVSQDEMTIENTSPEPCVAAEHEEEELEPGEVKGTISRRRIATPEQVCFPLQHGWRREVRIKKGSHRWQGETWYYAPCGKRMKQFPEVIKYLSKNAGPFVRREHFSFSPRMPVGDFYEERNTAEGLQWVLLNSEEIPSRIIAITGKRGRPRNLEKAKAKEQKAKRGRGRPPKVKMIDLLSKADAKLLRKLENQDILSDSEKVQLCKLKKKMRRKARNQEAKLEAAKKLKEIKEKEEKKQKIQKAKNQEKAKNQEKKRTRRQPKQKAPVVQKPDRKLLAQQRRLEERKRQQFILEELKKPTEDMCLPDHQQLPDFPCVPGLFLPSCAFSDCLTTVEFLHSYGKVLGLDEAKDIPSLCTLQEGLFNVGDSLGEVQDLLVKLLQAAMINPGLPPYCQSLKILGEKVSEIVLSRENVSEPLRIFLEAYGGDIELCDSLRSHPFQAHAPHIKTAILAFIVNELNASSLIISEIDKTLENMSHYRKHKWIIEGKIRRLKFALSKRKSSEESQITTTEVSLRRRSERNAEENDELDSIDESAIQKDYVQEEVDIPPSTSVVELERQIEKLTKRQMFFRKKILGSSQRLRTVCLGQDRYRRCYWMLPHLGGIFIEGLPESAEPTEEAALGNDIEASSVKTEDKSFGSLCKTSGHPRNSTAEPEQNSTSCHCSDSKDKEPSGVTDQFPNSVPLTNNQQDLSQSVFLSWLTKNQTSIMDSTVLTPESSPPHSESTPIISSEATEKPEQWLPLISRTPCRNHNQGLSTHSSNRLSPPSPTAATSVKQVNEFTEEAQTFATSLPSNSTPCHVCYNSGKSSTASHEITLTSNILHDSEKEKRRGRRPSKLLKQIEQKYYNQLIERPIPAGVRQKWWWIKDPAMLESLLKALHPRGIREKTLHKHLTKHLQHLKEMCARPASDALFKFTPVDGHRVSQETLDRWSVTDLTFQVDLSALQWVEDLEQRVMLSDLQQRGWSPSAPDSVRTDLKYYEHQLEPADDITVKVKREDCRLYRESSNPLDLAVLRILCLEENVERKYLKEPLWLFSEVQHEKVVITNPEDPLSTTEIEYSITSRLRLWRQTVERCRSAAQLSLCLQQLERSIAWERSLNKVTCLYCRKGDNDELLLLCDSCDRGCHTYCHRPRMNEIPEGDWFCPTCISLQSESEFLRSSGSSKRIRKCTVRFTEDSPSKPSRRREHPTASQFSPGESPASKKRRMGTRSQSPDLTFCEIILMELESHEDAWPFLEPVNPRLVPGYRKIIKNPMDFSTMRHKLLNGNYSRCEEFAEDAELIFSNCQLFNEDESDVGKAGLILKKFYDARWEEFSQERNQISL
What is the function of this protein?
Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing.  In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription.  Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac), leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac.  Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity).
What are the official names of this protein?
Bromodomain adjacent to zinc finger domain protein 2A, Transcription termination factor I-interacting protein 5, TTF-I-interacting protein 5, Tip5.
What is the protein family that this protein belongs to?
Belongs to the WAL family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YPTC4_CHLRE
Sequence: MSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLASWLEDARQHANPNMTIMLIGNKCDLTHRRAVTTEEGEQFAKEHGLIFLETSARTAHNVEEAFINTAKEIYKKIQDGVFDVSNESYGIKVGYGGGNAGPQTVKPGEGGAAKSSSCC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
GTP-binding protein YPTC4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: VMA21_DANRE
Sequence: MQNYDKKEVGSVPGAMPDFRGNDGSLVSVLKTLLFFTILMITLPIGLYFTSKSLLFEATLGYSSNDSYFYAAILAVLAVHVVLALFVYVAWNEGSRQWREGKQD
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein vma21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: Y1377_STRT2
Sequence: MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHAARVLPGYEPDNKIKLLQEFKDQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKFNELNIYVGSVVITQYSGQPAADAFRNQLEKNGITSYIHYPIKGYPTDINHIISPEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCLSNMYHDQINGIKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLETYGKTTVNYNRDIEIFPVLKRMLERILGESPYASPTDMGVNMVGFAITDDEAAKEASKQEIIRRYYQTVLDFKNERVPETAVKKIELLMNDLGITPEDRQVVVAARAKAEETGGSALALELPNGQIVTGKNSELFGPTAAALINAIKTSAGIDKDTRLIEPEVVKPIQDLKIDHLGSRNPRLHSNEILIALAITAANNADAARAMKELSNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDKLYRK
What are the official names of this protein?
UPF0371 protein stu1377.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: ISPD_VIBPA
Sequence: MSENVSSHIAIVPAAGVGSRMKADRPKQYLLIDGKTVLEHTVEKLLAHPQIAKVVVAVTEGDPYYPELSIALHPDVIRVAGGKERADSVLSGLNYVSAQLPCEWVLVHDAARPCVTLNDIDRLIDVCCAHPTGGILASPVRDTMKRANKENNIDHTVDREALWHALTPQMFKTQQLTRALADALQQGVAITDEASALEWLGETPALVQGSANNIKITQPEDLALAEFYLSRERG
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: HSLV_PSELT
Sequence: MEWKSTTVLVVSRNGKTVMAGDGQVTYGNTVMKHGARKIRKIGDGQVLAGFAGSVADAMALFDRFESKLKEWGGNLTKAAVELAKDWRTDRVLRRLEALLLVADRDNVLIISGTGEVVQPDDNVAAIGSGAPYAIAAARALIRNTDLDAREIVEKSMQIASEICIYTNGNITIEEI
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_CHESB
Sequence: MADILRKIEAYKREEIAAAKQALPLAEQAARARDAAPIRGFAAALRSKHAAGQFALIAEVKKASPSKGLIRADFDPPTLAKAYEDGGAACLSVLTDRPSFQGAPEFLTAARAATNLPALRKDFMFEPYQVFEARAWGADAILIIMASVSDDEAINLSETAGELGMDILLEVHDEAELERALKLPSPLIGINNRNLRTFETTLETSERLAPLVPEDRVIVGESGIFTHADCLRLKKVGISTFLVGESLMRQNDVEAATRSLLGLQRNIEAVS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: GR6_HUMAN
Sequence: MKEALHQIVVRCSELVSSTSLPRLSVSRLQGPPDSQPLGTLGQGGWKLLGIVGSLAPETLGGLGTEFGPCTHPLPFDMVRERERDDELRQGWLLQCPQCARTLLCHCGPFLTPPSQTSSSGFQLCSLKPSGSLVTATEPLSNFAFSYFP
What are the official names of this protein?
Protein GR6.
Protein: VKT34_CYRHA
Sequence: MGTARFLRAVLLLSVLLMVTFPALLSAEHHDGRVDICRLPSDSGDCLRFFEVWYFDGTTCTKFVYGGYGGNDNRFPTEKACMKRCAKA
What is the function of this protein?
Dual-function toxin that inhibits both serine proteases and voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hhn1c, U15-TRTX-theraphotoxin-Hhn1c, Kunitz-type serine protease inhibitor HNTX-0314934.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCDA2_ORYSJ
Sequence: MAARPVSSTTSTCRPCRPAQAAASKPSTSSSPGTGVLVGVPRERGSSVSKAAIRGARLEAAARCSLVRQRPMLLATVAVGSLVAAGAANATEIGDSLLGSSGLALADLSIGDWFGNLLYSAGQQANEAVQDQLSALSFTSLAVIFGAGLVTSLSPCTLSVLPLTLGYIGAFGSGKDRSEVVGNSVAFSLGLATTLAILGVAASFAGKAYGQVGQGLPVAASGLAVIMGLNLLEVIELQLPSFFSDYDPRAAAANLPSSVQAYLAGLTFALAASPCSTPVLATLLGYVATSRDPIVGGSLLLTYTTGYVAPLLIAASFAGALQSLLSFRRYSAWINPISGAFLLGGGVYTLLDRLFPATSMVM
What is the function of this protein?
Probably involved in the transfer of reducing equivalents from stroma to thylakoid lumen and required for the biogenesis of the plastid cytochrome b6f complex.
What are the official names of this protein?
Cytochrome c-type biogenesis ccda-like chloroplastic protein 2, Cytochrome b6f biogenesis protein CCDA2.
What is the protein family that this protein belongs to?
Belongs to the DsbD family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SADA_DICDI
Sequence: MKSQKIGSMILLIGILLAIFNFAYSDDDIERFSINPEKPISFTSDQPGFPTSADFPIGSILANSFYSFGGDVNYFQLNISLMEEFSKDGNTGSQATWNQYTSVPVSPISSAVTANRVYTMSIGSLNRVKKGDITSMESTDFLNDEKYSSLVTTLNGGVSYGDDVFFLSSKSATGEAVLIHINDTATGTFGTSSYDEILLDAAINDPSSITVDSKLGLAFIGDSDGDILVFNMTLKAKIAIYSNSSIANLRSSGVVDEERQLLYICGQAGGMNSYITQVDIFHYSATDITLLHSFTILGSLCPSAGIDVKGGQLFFSTTTSSGSQLIGTDTSGGNTGSLSENIANTQSVAISVDSITKTISVFYPDSVFYGTFKSICPSDCSGHGECNYGTCVCDHNYQGQGCEEELCLTLNNCTGTDNGKCENGFCYCSSEWEGAQCEIRRCKDSCNGYGTCNTANYTCVCDSAHMGETCNELVPPPPCTYYTDSESCLSRTTCGWCEVDGLCKEGDRYGPFEGFCRTWFFDTNVETGVIALACIFIAFVGILYIIDIGTTVPIDIKRAKDYAEENKSGQFPKATHEEASVLWWRDQRSHKAWTFMDQFQLISLVSHIGVVFPSRFISFTEYLDWSNLGIPLPPSINPPQIWSVPTDWTSNTARTILSMAQYENSLGSGDLYLLPNILFWFGLLLGVFLVPLLLAYAIISFMESLIHWKEVVTNRLIHVLVRILTFGYIGVLIAASFAMVTPLHDYRIIIPGAIIFVLYGIGLPIAIWFLLAVPEARLHNPTFKQRFGCLYVHYKPKTDHRFVVFMFIKRFIMAVIIGILSFKPMTNYPLTGTDLAVPIVQVVVIDIALIGYAVLLFIRKPYFDHYQLWLEYLLTAINIVTVSLSLTHIKSPSAAGELIACLIQALALVACIAAYVVAWLQMRSSFIKKVKKYLCCCCKSSKSSGEIDLSKK
What is the function of this protein?
Involved in substrate adhesion, myosin-independent cytokinesis, organization of actin cytoskeleton, and phagocytosis.
What are the official names of this protein?
Substrate-adhesion molecule.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL13_BRUMB
Sequence: MATFSQKPAEVVKKWVLIDAEGLVVGRLASLVANRLRGKHKATFTPHVDDGDNVIIINADKVVLTGKKYTDKKYYWHTGHPGGIKERTARQILEGRFPERVLEKAIERMIPRGPLGRRQMKNLRVNVGPNHQHEAQQPEVLDVAALNRKNKGNA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: HEM3_BLOFL
Sequence: MQAKILRIATRKSPLAICQACYVCNKLKHYHPHIQTELIPIITTGDTSLHTVSKTNKIKKGAFIKELEYALIEHRADIAVHSMKDVTVLLPKELIIPVLCKRHDPRDAFVSIQYPNIHSLPTGSIIGTSSLRRQCQIRAQRSDLILHDLRGNINTRIKKLHQGQYNAIILAVAGLTRLKLTKYIQTYIDPSELLPAMGQGVIAIECRINDINTISLLSPLYHKETSLCIKSERAVTTYLESYCRLPIASYAEIQNNQIWLRALIGLPDGSIIIRTEGIASLDKAEELGLNLAKDLLIQFKKNTHFDINSIK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PUR5_STRFR
Sequence: IRAGDAVIAMASSGLHSNGYSLVRHVLFDGAGYALDREIPEFGRTLGEELLEPTRIYSLDCLALTRTTEVHAFSHITGGGLANNLARVIPDGLHATVDRATWTPAPVFGLVGSAGSVERTELEKTLNMGVGMIAVVAPEGADAALATLADRGVDAWICGEITDRGESGEHAEAVALTGDYAV
What are the official names of this protein?
Putative phosphoribosylformylglycinamidine cyclo-ligase, AIRS, AIR synthase, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACES_NAJOX
Sequence: SELKVATQTGFVRGLSLPVLAGHVSAHLGVPFAEPFLRPEPVKPGAEMWNPNLNIWVPSGRVGAFXFLTVTLFGESAGAASVGMXLLSTQRAILQSGAPNAPWAQVQPAESRFPFVPVIDGEFFPLGVNKDEGSFGVPGFSKXXESLINQAVPHANDIYTDWQDQDNGGLPLTGNPTXPHN
What is the function of this protein?
In venom, its toxic role is unclear: it could result in less musculatory control by rapidly hydrolyzing acetylcholine, or that it works synergistically with alkaline phosphatase (ALP) in paralyzing prey through hypotension.  In muscle, it terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.  In liver, its function is unclear: it could serve as a safeguard against any diffusion of acetylcholine from synapses into the circulation.
What are the official names of this protein?
Acetylcholinesterase, AChE.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Synapse. Secreted. Cell membrane; Peripheral membrane protein.
Protein: PLSY_COXB1
Sequence: MAFIISIIIAYLLGSLSFAVIVAKLMKLPDPRTTGSGNAGATNMLRVGGRQAAFYVLLGDAAKGLIAVLIARFLNVQGVSLAFVGLVAVLGHLFPVYFKFRGGKGVATMMGVLLGLSFWIGLFVIATWVIVVSIFRYSSVAALVSAVAAPIYTIIAGRTDYLFPVLIIAILIIWKHWENFQRLRKGTEDKVKL
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYF_SYNY3
Sequence: MRNPDTLGLWTKTMVALRRFTVLAIATVSVFLITDLGLPQAASAYPFWAQETAPLTPREATGRIVCANCHLAQKAAEVEIPQAVLPDTVFEAVVKIPYDLDSQQVLGDGSKGGLNVGAVLMLPEGFKIAPPDRLSEGLKEKVGGTYFQPYREDMENVVIVGPLPGEQYQEIVFPVLSPDPAKDKSINYGKFAVHLGANRGRGQIYPTGLLSNNNAFKAPNAGTISEVNALEAGGYQLILTTADGTETVDIPAGPELIVSAGQTVEAGEFLTNNPNVGGFGQKDTEVVLQNPTRIKFLVLFLAGIMLSQILLVLKKKQIEKVQAAELNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MATRX_RABVD
Sequence: MNFLRKIVKKRKDEDTQKPSPVSAPPDDDDLWLPPPEYVPLKEFTSKKNMRNFCINGEVKVCSPNGYSFRILRHILRSFDEIYSGNHRMVGLVKVVIGLTLSGAPVPEGMNWVYKLRRTLIFQWADSRGPLEGEELEHSQEITWDDDTEFVGLQIRVSARQCHIQGRIWCINTSSRACQLWSDMSLKTQMSEEDKDSSLLLE
What is the function of this protein?
Plays a major role in assembly, budding and uncoating of virion after membrane fusion.  Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form.  Inhibits viral transcription and stimulates replication.  Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons.
What are the official names of this protein?
Matrix protein, Phosphoprotein M2.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus matrix protein family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein. Host cytoplasm.
Protein: HISZ_ALBFT
Sequence: MSAWVLPDHIADVLPSEARHIEELRRSLLDTARCYGYELVMPPLLEHLESLLTGAGAALDLQTFKLVDQLSGRMMGLRADSTPQVARIDAHLLNRPGVTRLCYCGPVLHTRPGAPHASREPLQFGAEIYGHAGLEADLEILMLALDCLKVVKVASPSVDLADARIVHALLKGVPVEIALAEQIYAALAAKDASELAVLTKKFPSSSRQGLLALVQLYGDEKVLLEAEKALQPLPAITESLSNLKWLASQLDGAKVSFDLADLRGYAYYTGTRFSIYAAGASDALVRGGRYDEVGAVFGRNRPAAGFSLDVKALVGVLPARPLRAAIRAPWREAADLRVAIASLRAQGETVVCVLPGHESEVDEFRCDRELVPRNGQWIVASI
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_BURO0
Sequence: MARFQEFYKEKVVPGLIEKFGYKSVMEVPRITKITLNMGLGEAIADKKIIENAVGDLTKIAGQKPVVTKARKAIAGFKIRQGYPIGAMVTLRGQAMYEFLDRFVTVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIDYDKIDALRGLNISITTTAKTDDEAKALLASFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: HILS1_MOUSE
Sequence: MAQMVAGDQDAGTLWVPSQSESQTESDISTQSLRKPTMSYVILKTLADKRVHNCVSLATLKKAVSITGYNMTHNTWRFKRVLQNLLDKGMIMHVTCCKGASGSLCLCKERALKSNHRAKRCQDRQKSQKPQKPGQRESEPCQLLLSSKKKNDQLFKGVRRVAKGNRHCHY
What is the function of this protein?
DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa.
What are the official names of this protein?
Spermatid-specific linker histone H1-like protein, TISP64.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.