PharMolix/UniProtQA huggingface dataset:
Protein: ATPE_STRTD
Sequence: MAQMTVQVVTPDGLKYDHHASFIHAVTKDGQIGILPGHINLIAPLEVDELKVRRVDDESHVDWIAVNGGIIEVKDDFITIIANSAERDRDIDVSRAERAKQRAERVLEEETKRVLEEATKSDRNDDVQRAQIALRRALNRINVGTKIR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TEC1_YEAST
Sequence: MSLKEDDFGKDNSRNIESYTGRIFDVYIQKDSYSQSALDDMFPEAVVSTAACVKNEAEDNINLIDTHPQFELVNTGLGAKSDDLKSPSAKATFTDKQRKNEVPNISVSNYFPGQSSETSSTTESWTIGCDKWSEKVEEAFLEALRLIMKNGTTKIKIRNANFGRNELISLYIKHKTNEFRTKKQISSHIQVWKKTIQNKIKDSLTLSSKEKELLHLIEHGAEQTTENSNLFYDIFEEIIDSLPSVSDSGSLTPKNLYVSNNSSGLSVHSKLLTPITASNEKKIENFIKTNAASQAKTPLIYAKHIYENIDGYKCVPSKRPLEQLSPTELHQGDRPNKASFSNKKAILESAKKIEIEQRKIINKYQRISRIQEHESNPEFSSNSNSGSEYESEEEVVPRSATVTQLQSRPVPYYKNNGMPYSLSKVRGRPMYPRPAEDAYNANYIQGLPQYQTSYFSQLLLSSPQHYEHSPHQRNFTPSNQSHGNFY
What is the function of this protein?
TEC1 is involved in the activation of TY1 and TY1-mediated gene expression.  It is not involved in mating or sporulation processes.
What are the official names of this protein?
Ty transcription activator TEC1.
What is the protein family that this protein belongs to?
Belongs to the TEC1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2212_AERHH
Sequence: MFGKGGMGNLMKQAQQMQERMQKMQEQLAQMEVVGEAGAGMVKVTMAGSHSVRRIEIDPSLMEDDKEMLEDLVAAAVNDAVRRVEEQNKSKMGELTGGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein AHA_2212.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RECR_CERSK
Sequence: MAEAPGDIERLIELMARLPGLGPRSARRAVLLMLKKRGAVMAPLAQAMAEVATSARDCVRCGNITNADLCGICRDERRATGELCVVEDVADLWALERAGAFRGRYHVLGGVLSALDSVGPEELRIPRLAERVREEGISEVILALNATVDGQTTAHYIADVLEPSGVQVTSLAQGVPIGGELDYLDDGTIGAALRARRRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RLMF_PSEPK
Sequence: MTPNKPTLHPRNRHQGRYDFPSLIKAHPDLARFTITNPHGKPSIDFANPEAVRVFNRALLKAQYGIQHWDIPADYLCPPIPGRADYIHVAADLLADDNAGDVPRGAQVRALDIGVGANCIYPLLGYSDYRWRFLGSDIDPVALASAKAIVQANGLGKAITLRQQANRAHILSGLLQEGERFDLTLCNPPFHASRDEATRGSQRKWKNLGKQDPKRKLPVLNFGGQNNELWCEGGEIRFVTQLIGESVQYAERVLWFTSLVSKASNLPGIEAALKKSGAKAVRIIEMGQGQKQSRMVAWSFLDDAARQAWHAQRKSQA
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_CORGL
Sequence: MTNTQTEIINELKVSPAIDVAKEVEFRVQFLVDYLRASHTKGFVLGISGGQDSTLAGRLTQLAVERIRAEENSTDYVFYAVRLPYAIQADEDDAQVALEFIAPDKSVTVNVKDATDATEATVAAALELPELTDFNRGNIKARQRMVAQYAIAGQLGLLVIGTDHAAENVTGFFTKFGDGAADLLPLAGLSKRQGAAILEHLGAPSSTWTKVPTADLEEDRPALPDEEALGVSYADIDNYLENKPDVSEKAQQRIEHLWKVGQHKRHLPATPQENWWR
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: KDPB_YERPY
Sequence: MTHKQRAIFEPTLVRTALLDAVKKLDPRVQWRNPVMFVVYLGSWLTTLIWLAILSGHTTGSAMFTGSIALWLWFTVLFANMAEALAEGRSKAQAASLRGVKKTSWAKKLSEARVDAPQEKVSADSLRKGDLVLIEAGDTVPCDGEVLEGGASVDESAITGESAPVIRESGGDFSSVTGGTRVLSDWLVVECRVNPGETFLDRMIAMVEGAKRRKTPNEVALTILLVALTIVFLLATATLYPFSVFSVEASQAGSPVTITVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFLPAPGVTEQQLADAAQLSSLADETPEGRSIVVLAKQRFNLRERDLHSLNATFIPFSAQTRMSGVNVQERMIRKGAVDAIRRHVESNQGHFPPAVDDLVASVARTGGTPLVVAEGSRVLGVVALKDIVKGGIKERFAELRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMQLHSPSSAILSAVIFNALVIVFLIPLALKGVSYKAMSAAALLRRNLWIYGLGGLLVPFVGIKLIDLLLTALNMG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL35_XANAC
Sequence: MPKIKTNRAAAKRFRKTASGKYKCGHANRSHILTKKATKRKRNLRQTNHVRAEDAGRLDRMLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: OBG_CAMHC
Sequence: MFVDNVKFHTKAGKGGAGCVSFRREKFILFGGPDGGDGGDGGNVYFKADKNSHTLSKYKGKKLLKAENGAGGEGRKKFGKKGADLVLIVPPGTSIYDDKTGELLFDLKEDGEKVLALKGGKGGLGNVHFKSPVNQRPEYAQPGLSGEEKDIRLELKLIADVGLVGFPNVGKSTLISTISNAKPEIANYEFTTLTPKLGMVEVDEFSGFVMADIPGIIEGASEGRGLGIKFLKHIERTKILLFMIDMSNYRTLKEQFNALKEESTKFSKNLANKLYAIALTKADTVENTDKMLTEFCDEFGFGSRQIPNEKGEFDKTKPVFVMQISSAANKNIKELKFALLEILKAQN
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAI2_ARATH
Sequence: MGVVEEAHNVKVIGSGEATIVLGHGFGTDQSVWKHLVPHLVDDYRVVLYDNMGAGTTNPDYFDFDRYSNLEGYSFDLIAILEDLKIESCIFVGHSVSAMIGVLASLNRPDLFSKIVMISASPRYVNDVDYQGGFEQEDLNQLFEAIRSNYKAWCLGFAPLAVGGDMDSIAVQEFSRTLFNMRPDIALSVGQTIFQSDMRQILPFVTVPCHILQSVKDLAVPVVVSEYLHANLGCESVVEVIPSDGHLPQLSSPDSVIPVILRHIRNDIAM
What is the function of this protein?
Involved in seed germination and seedling development.  Essential for plant responses to karrikins, a class of butenolide compounds, structurally similar to strigolactones, released from burning vegetation that stimulate seed germination and enhance seedling photomorphogenesis.  KAI2 is not required for strigolactone-mediated responses, but MAX2 is necessary for responses to karrikins and strigolactones (PubMed:20864454, PubMed:22357928, PubMed:23142794, PubMed:23301669).  Lacks detectable hydrolase activity against karrikin (PubMed:23613584).  Karrikin binding induces a conformational change (PubMed:23613584).
What are the official names of this protein?
Probable esterase KAI2, Protein DWARF-14-like, Protein D14-like, Protein HYPOSENSITIVE TO LIGHT, Protein KARRIKIN INSENSITIVE 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Note=Weak expression in the cytosol.
Protein: HSY1_SOLLC
Sequence: MISFFRAFFLIIIISFLIFVGAQARTLLGNYHDDEMLIELKLESGNYGRTPYKTPPPPTSSSPTHQEIVNGRHDSVLPPPSPKTDPIIGQLTTITTTPHHDDTVAAPPVGGRHDYVASPPPPKPQDEQRQIIITSSSSTLPLQASY
What is the function of this protein?
Activates a lipid-based signal transduction pathway in which linolenic acid is converted to jasmonic acid, a potent activator of defense gene transcription.  Induces synthesis of proteinase inhibitors I and II in leaves when supplied through cut stems.
What are the official names of this protein?
Hydroxyproline-rich systemin, Defense-signaling glycopeptide hormone.
What are the subcellular locations of this protein?
Secreted.
Protein: NASP_MOUSE
Sequence: MATESTAAAAIAAELVSADKIEDAPAPSTSADKMESLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNVDEEAREELREQVYDAMGEKEAKKAEGKSLTKPETDKEQESEVEKGGREDMDISEPEEKLQETVEPTSKQLTESSEEAKEAAIPGLNEDEVASGKTEQESLCTEKGKSISGAYVQNKEFRETVEEGEEIISLEKKPKETSEDQPIRAAEKQGTLMKVVEIEAEIDPQVKSADVGGEEPKDQVATSESELGKAVLMELSGQDVEASPVVAAEAGAEVSEKPGQEITVIPNNGPVVGQSTVGDQTPSEPQTSAERLTETKDGSSVEEVKAELVPEQEEAMLPVEESEAAGDGVETKVAQKATEKAPEDKFKIAANEETPERDEQMKEGEETEGSEEEDRENDKAEETPNESVLEKKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYIQAVEEFQACLSLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFGKSIDVIEKRMAVLHEQMKEAEGSFTEYEKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPSGAGASVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVSSGKEVSENMEAEAENQAESQTAEGTVESAATIKSTAC
What is the function of this protein?
Required for DNA replication, normal cell cycle progression and cell proliferation.  Forms a cytoplasmic complex with HSP90 and linker H1 histones and stimulates HSP90 ATPase activity.  NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.
What are the official names of this protein?
Nuclear autoantigenic sperm protein, NASP.
What is the protein family that this protein belongs to?
Belongs to the NASP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y768_THEKO
Sequence: MKFIKETKEGVLIMIYVQPKAKKNAIEGVDGWRGRLKVRIAAPPVEGKANKEVVKFFSKLLGAEVNIVRGETSREKDLLVKGLSVEEVRKKLGV
What are the official names of this protein?
UPF0235 protein TK0768.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RL37_METAC
Sequence: MSKGTSSMGKRQKRTHAKCRRCGSVSFNVHTKQCTSCGFGKTSRMRTYKWQAKCKY
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: EF1A2_HUMAN
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha 2, EF-1-alpha-2, Eukaryotic elongation factor 1 A-2, eEF1A-2, Statin-S1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPX_JANSC
Sequence: MASNSGNDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREETKSAGLKSDDGVPTPQEICGVLDDYVIGQAHAKRVLSVAVHNHYKRLNHSDKSDIELAKSNIMLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASEYNVERAQRGIVYIDEVDKITRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDKIIAQRGKGSAMGFGADVRDPDSKSVGEYFKDLEPEDLLKFGLIPEFVGRLPVIATLEDLDEDALVTILTGPKNALVKQYQRLFELEDVKLTFTDDAMSAIAKRAILRKTGARGLRSIMEDILLDTMFDMPGAEGVEEVVVNEEAVNSDTQPLMIYAERKADEPASAS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YD306_YEAST
Sequence: MANKSRPKKIKAPYRKYVAGEGFSSTRNDNKAKEFTITIPEDAELIETPQGSYYYDETNDTIVKLTRLSNEKKDKKGRKQSPSSSSTSSSKGEKNGKVIESEEARMHSVSVKMVLPWEIQHRIIHYLDIPEKEEKLNKTANGKKTTTGINMNYLLVCRNWYAMCLPKLYYAPALTSKNFNGFVDTIIINKKKNLGHYVFELNLSTILQSGRNSFVSKLLRRCCSNLTKFIAPQTSFGYAPLISLKSCHDLKFLDLGLVSETVKLKELFSAIKNFTKLTHLSFPRSSIDCQGFQDIQWPQNLRYLKLSGGITNEFVIDTKWPTTITTLEFSYCPQITELSIYSLLSQIGDNLKHLFFHYPMPSLAENSLDHVFTYCANLISLQLMVDYCSKWCFSEFMLSKLVEYDRPLKTLYLECSGSLGLASKIHPDDLTIAILESRLPCLKNICVSPKLGWNMKSDEVADLVVSLEDQDGSLYLNY
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Probably recognizes and binds to phosphorylated target proteins (By similarity).
What are the official names of this protein?
F-box protein YDR306C.
Protein: FMT_PORGI
Sequence: MKKEELRLIFMGTADFAVPALRALVENGYQVKAVVTMPDKPMGRGHKVSPSMVKLYAQELGLPILQPDNLNEESFLDELRTYQPHLQIVVAFRMLPRSVWQMPPMGTINLHGSLLPMYRGAAPINHAIRHGDTETGVTTFRLRHEIDTGEVLLQEKLPIGHEETFGELYERMATLGASVLVHTVDLFLEGEPVSIPQEQLPGYVDARPAPKIFKDDCRIDWDKPAEEVHNFIRSISPAPTAWTKLHRPRMESIVLKIYRTQVIEREPRHRGRFGSIIWDKKNLDVMTRKGVIRILSLQMPGKKQMDAASFLNGFALSSDMYIE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Y1601_STAAE
Sequence: MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
What are the official names of this protein?
UPF0173 metal-dependent hydrolase NWMN_1601.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: WCAF_SHIFL
Sequence: MQDLSGFSVPKGFRGGNAIKVQLWWAVQATIFAWSPQVLYRWRAFLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYAWVGDDVNLYTLGEITIGAHSVISQKSYLCTGSHDHASQHFTINATPIVIGEKCWLATDVFVAPGVTIGDGTVVGARSSVFKSLPANVVCRGNPAVVIRERVETE
What are the official names of this protein?
Putative colanic acid biosynthesis acetyltransferase WcaF.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: GUAC_BACCR
Sequence: MMENVFDYEDIQLIPAKCIVNSRSECDTTVTLGKHKFKLPVVPANMQTIIDERIATYLAENNYFYIMHRFQPEKRISFIRDMQSRGLIASISVGVKEDEYEFVQQLAAEQLTPEYITIDIAHGHSNAVINMIQHIKKHLPESFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTHGDVAKSIRFGATMVMIGSLFAGHEESPGETIERDGKLYKEYFGSASEFQKGEKKNVEGKKMFVEHKGSLEDTLIEMEQDLQSSISYAGGTKLDAIRTVDYVVVKNSIFNGDKVY
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: DXR_PROM5
Sequence: MKYITVLGSTGSIGTQTLEIVRELPNKFKVVALSAGRNIDLLTEQVSQHKPEVIAIDDENLLTDLKNNINNLGISNPPIVLGGREAINSVAAWDSADTVITGIVGCAGLIPTMSAIKASKNIALANKETLIAAGSVVIPALKENKSRLLPADSEHSAIFQCIQGLPNYENADFVTGQIPNGLKAIHLTASGGAFRDWAVEDLKNVTVEDATSHPNWSMGRKITVDSATLMNKGLEVIEAHYLFGTPYQNIEIVIHPQSIIHSMIEMEDSSVLAQLGWPDMKLPILYAMSWPERFRTNWKRFNLTEIGQLTFKKPDEVKYPCMGLAYSAGKCSGTMPAVLNAANEMAVDQFLKEKISFQEIPTFINKTCEAHINKLNLNPNLEDILEVDNWARIFVQEEIKKGKKYINVE
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: PGM_KOMXY
Sequence: MPSISPFAGKPVDPDRLVNIDALLDAYYTRKPDPAIATQRVAFGTSGHRGSSLTTSFNENHILSISQAIADYRKGAGITGPLFIGIDTHALSRPALKSALEVFAANGVEVRIDAQDGYTPTPVISHAILTYNRDRSSDLADGVVITPSHNPPEDGGYKYNPPHGGPADTDITKVVETAANDYMAKKMEGVKRVSFEDALKAPTTKRHDYITPYVDDLAAVVDMDVIRESGVSIGIDPLGGAAVDYWQPIIDKYGINATIVSKEVDPTFRFMTADWDGQIRMDCSSPYAMARLVGMKDKFDIAFANDTDADRHGIVSGKYGLMNPNHYLAVAIEYLFNNRENWNASAGVGKTVVSSSMIDRVAKEIGRKLVEVPVGFKWFVDGLYNGTLGFGGEESAGASFLRRAGTVWSTDKDGIILGLLAAEITARTKRTPGAAYEDMTRRLGTPYYARIDAPADPEQKAILKNLSPEQIGMTELAGEPILSTLTNAPGNGAAIGGLKVSAKDGWFAARPSGTENVYKIYAESFKSAAHLKAIQTEAQDAISALFAKAAQKNAG
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase, PGM, Glucose phosphomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ZIPA_SERP5
Sequence: MMQDLRLILIVVGAIAIIALLLHGLWTSRKERSSLFRDRPAKRSKKEREQSPIDELDEGVGEVRVRSAHPEDEPSFGHFDAAREEPVVAPKPAPAAEPAPRAVQPAAHQTPPPLSQRPDYDDILLDNYAQEEDDEPQQPAPRREPRVDDLPPVAPAAEPAFHAEPAHQPQPEVKPAVAHEPQPAPAAIKPAKLKETVLVLHVTAHQGGVIGGEILLQSVLQAGFQFGEMGIFHRHISPAGSGPVLFSLANMVKPGSFDPEMMSDFSTPGVSMFMMVPSYGDANQNFKLMLQSAQRIADDVGGVVLDDERRMMTPQKLETYKARLREVLENNA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: RL10_YERP3
Sequence: MALNLQGKQAIVAEVKEVAKGALSAVVADSRGVTVDKMTELRRAGREAGVHMQVVRNTLLRRIVEGTPFECLKDTFVGPTLIAFSAEHPGAAARLFKAFAKDNAKFEVKAAAFEGELIPAAQIDRLATLPTYEEAIARLMGTMKEAAAGKLVRTLAALRDQKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: LIP1_YEAST
Sequence: MSQPTPIITTKSAAKPKPKIFNLFRVCFISLLLIAAVEYFKYGTRINYEWFHCTPIKEPQSGSVIKLWARGGPSCDKRGEYKTIVKRITRDYEPNDEHLSFCIIENDNVPPVHYPIHEDKGEPGYVAYVGYDTDSELVQELCADSTIYHM
What is the function of this protein?
Component of the ceramide synthase complex required for synthesis of ceramides.
What are the official names of this protein?
Ceramide synthase subunit LIP1, LAG1/LAC1-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the LIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: KAPCB_BOVIN
Sequence: MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCGKEFCEF
What is the function of this protein?
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs.  PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, and differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.  Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.  Phosphorylates GPKOW which regulates its ability to bind RNA.
What are the official names of this protein?
cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Membrane; Lipid- anchor. Nucleus. Note=Translocates into the nucleus (monomeric catalytic subunit). The inactive holoenzyme is found in the cytoplasm.
Protein: PROB_RHOBA
Sequence: MNESSEANDLAIRRQIIDETKCVVVKVGTRVLTTSDGKLDLERVDRLAEQLCRIADTGRQTIMVSSGAVGAGVAKLGLPQRPTDLKSLQAIAAIGQADLIGAYEKSLQKRGRHAAQVLLTRNDLRRRSGYLHVRNALNGIDELGAIAVVNENDSVAVSELKTTFGDNDRLAAQVAGLFNDVMLILLTDVSALYDGHPDEKDSQPIHMVHDVDDGVMALVDDQVSTVSKGGMGGKLRASKLANSHGHPTIIGSGTEEFVLDRIFAGDAVGTLFVPPKRSLKGRRRWIGSSANVAGTLFLDQGAVDAIQKHGRSLLAIGIQRVEGTFAHGNVVRLVGPNGEEFGRGLSNYRSHEVARIAGKPSEQIEWILGHRPYENVIHRNNLVLRIVPE
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_ERWT9
Sequence: MQKFDTKTFQGLILTLQDYWARQGCTIIQPLDMEVGAGTSHPMTCLRALGPEPTAVAYVQPSRRPTDGRYGENPNRLQHYYQFQVIIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQSLLALEKPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNNKK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_CULQU
Sequence: MMLTRLTRLVTGTNTAPSLHCRWYAAATAEKSALATLRKKTGYTFANCKKALEMHGNDLAKAEQWLKEQAQTLGWSKATKLEGRNTSQGLVGVLVRDNIGAMVEVNCETDFVARNQSFQSFVQAASAACVRYVAQLETDANLTKHGLNSEALKQIKLEDGKSLGDHLALMIGTVGENASLNRAICYRAPAEVKLTGYVHPAPADDSTPDVPAFGKYGSLLAFRHTAVAEDSNGEAVARKVCQHVVGMKPTRLGDKARDEPAADKDDETCLIYQEYLADPSYTVGEVLEANQLEVVDFQRFECGEKVKAEEENVRATN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.