PharMolix/UniProtQA huggingface dataset:
Protein: OTC_DESVV
Sequence: MPKHFTRIRDLGFEGAWKVLERAKEMKDTGYRGRTLEGKVATLIFEKASTRTRISFEVAVRHLGGTTIFMTPAESQLGRSEPLRDTARVISRYTDCMIVRTFGQAKIDELASFGSIPVVNALTDEGHPCQVMSDVLTMYERTPDLSQVRVAWIGDGNNMANSWIEAAMYFPFELFMAFPEGYEPDRQLLGLALEAGAKIFLTRDPHMAIDGAHYVNTDVWASMGQEEEQKRREAAFKGFCIDGALMGRAHPDAKFMHCLPAHRGEEVTDEVMESPASIVWDQAENRLHMQKAILEWVFTE
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_SYNFM
Sequence: MRIIETVSEMQQQADDWRRAGKRIGFVPTMGYFHEGHLMLMRKVRGEADMVVASIFVNPAQFGPNEDLATYPRDLDRDLRLAGEVGVDVAFVPQVGEMYPDGYQTYVEVTKVTAPLCGRSRPLFFRGVATVVVKLFHIVKPHVAVFGEKDYQQLVTIRRMVKDLNLDIEILGHPIVREPDDLAMSSRNKYLTPEQRPLALRLSRALKAARARVALGERNGSVILKEVKELLDAGGEVRIDYAELRDPATMEEVGSMDGPSLLALAVFVGTTRLIDNCILRPAA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_PARXL
Sequence: MARGKFITFEGIDGAGKTTHLSWFRERLEQKVASTGRSVVMTREPGGTPLGEQIREIVLHQKMDLETEALLMFALRRQHLAEVIEPALARGDWVLSDRFTDATFAYQGGGRGLPRDKLETLERWVQGGFQPDLTVLFDLDPEVASERRSAARDPDRFESESEAFFSRTRAEYLRRAEEAPYRFAIIDSAQSIAQIQRRLEELIAIL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NADK_PYRHO
Sequence: MKFGIVARRDKEEALKLAYRVYDFLKVHGYEVVVDKETYEHFPHFKEGDVIPLDEFDVDFIVAIGGDGTILRIEHMTKKDIPILSINMGTLGFLTEVEPSDTFFALNRLIEGEYYIDERIKVRTYIDGENRVPDALNEVAILTGIPGKIIHMKYYVDGGLADEVRADGLVVSTPTGSTGYAMSAGGPFIDPRLDVILIAPLLPLPKTSVPMVIPGSSRIDIRMLTDREIILAIDGQYYEHLPPNVEITVVKSPRKTKFIRFTREIYPKYTIRIKERH
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.  It can use ATP and other nucleoside triphosphates (GTP,UTP) as well as inorganic polyphosphate (poly(P)) as a source of phosphorus.  NAD is the preferred substrate for the kinase, but NADH can also be used as phosphoryl acceptor.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase, Poly(P)-dependent NAD kinase, PPNK.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_LEPVR
Sequence: MIFSILEHILTHISFSVVSIVLTIYFLTLVVNLDEIIGFFDSSDKGIVITFFGITGLLFTRWIYSGHFPLSNLYESLIFLSWAFSIIHMVSYFNKKHKNHLNAITAPSAIFIQGFATSGLLNKMPQSAILVPALQSQWLMMHVSMMILGYGALLCGSLLSIALLVITFRKVRPTFWKKNIKTKFLLNELFSFDVLYYINERNSILLQQNSNFSFSRNYYRYQLIEQLDFWSFRIISFGFIFLTVGILSGAVWANETWGSYWNWDPKETWAFITWTIFAIYLHIKTNRNVRGINSAIVASIGFLLIWICYFGVNLLGIGLHSYGSFTPN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: S12A8_XENLA
Sequence: MGMIEPNRSVLLNGSMNGSENIKDLFHEDAQVSQLQSRPWWKIQLFVWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGIVLVSFVILVALVTVLSGIGVCERCSIGSGGVYSMVSTVLGGKVGGTIGVLYIFGQCVAGAMYITGFAESISDLLNLENMWVVRGISLAVLVGLLGINLAGVKWIIRLQLLLFLLLAVSTLDFVIGSFTHLDPENGFVGYSEELLRNNTFPDYTPGESFFTVFGVFFPAATGVMVGFNMSGDLQRPSINIPLGSLAAIGTSWFLYVVFVFLLGAICTREFLRYEFMIAEKVSLVGGLFLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPALSFLGRGKGPNKTPVAAIFITGLLTMAFVFIGQVNVLAPIVTINFMLTYSAVDYSYFSVTMSYKMQHSPKKNGRPNSRVMSSTQPLILNKSTSYGSNGTLLEFTKDMNQLFKPNHTEAPESTSSQEKDPKMFKFSKPRKPAKQTLQDSFQLDLHQGPEHGLESRLLVTDLAENESQNSKAEITEDKNQGVDPTESDEPDSEEDVDIQQPTEEQKGDSTVAQKVPEFEIQELSTSFYAKFCNHWVAFLGAILSIVIMFVIQWIYALVNLGVAIILYLYIGRVNPGLNPGAAANFSFFAWIRQGARTLCRKPHPKEQFVVTPSLLSVGMETTQLTEENEDFASRGRYHHSSIITQGQFIDRYN
What is the function of this protein?
Cation/chloride cotransporter.
What are the official names of this protein?
Solute carrier family 12 member 8.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y2060_ARATH
Sequence: MVAAKENKFLTVAPFECAWSDDLKFREAGRGCVAFDAFAHNDVTVVFRENVGTQHYHYKKDNSPHYIVIIGSNRNRRLKIQVDGKSVVDEEASDLCRCSLEFQSYWISIYDGLISIGKGRYPFQNLVFKWQDPKPNCNVQYVGLSSWDKHVGYRNVSVFPVTHNHILLWKQVDCREVRGDESGDEKVVEEGTGYDYEQWGLGNFLESWQLSDTVFLVGEEEMDVPAHKVILQASGNFPLRSSDGDVIQLRGVSYPILHALLQYIYTGRTQILESELAPLRDLSSKFEVMSLVRQCEESIDHFKLSKTAFDSCRKVKLLCPISHPLSGFMFPSAFPVDVGKLVKLYSTGEYSDIKIYLSDHSLTFQSHKVILSLWSVAFAKMFTNGMSESHSSTIYLTDVSPEAFKAMMNFMYSGELNMEDTVNFGTELIHLLFLADRFGVVPLHQECCKMLLECLSEDSVCSVLQVVSSISSCKLIEEMCKRKFSMHFDYCTTASLDFVLLDQTTFSDILESADLTVTSEEKILNAVLMWCMKAEESHSWGVIDEMMNYADPKSLFKERLQSLDDLLPHVRFSLLPYELLKRLENSNLSKEIPVFNRLLKEAASFLTSGLISPGNEPISRFQHRRSSFKELQYIRDGDSNGVLHFVGTSYGSHQWVNPVLAKKINITSSSPTSRFTDPKALASKAYAGTSFAGPRMEDGHISSWWVVDLGEEHQLMCNYYTFRQDGSRAFTRFWKFQGSMDGKTWTDLRVHEDDQTMCKAGQFASWPITAANALLPFRFFRLVLTGPTADTSTPWNFCICYLELYGYFR
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At2g30600.
Protein: KYNU2_EMENI
Sequence: MSNHVNGVNGVNGVNGVKPVFPENAASKEYAKALDAADPLASFRDKFIIPSKANIQSKRLAKPNISADPCIYFCGNSLGLQPKATAKYMEAHLDTWASIGVNGHFTKIEDSPLDPWWVMAEQAAGSMSKLVGAAPEEVIAMGTLTSNLHLLLASFYKPTATKHKILLDWKAFPSDHYAIESHIAWHDGLDPKKSMVLIGPDEGEYEIPTQKILSIIDEHADEAALILLPGIQYYTGQYFDINTITEYAHSKGLMVGWDLAHAFANVELKLHEWDVDFAVWCTYKYANAGPGSMGGLFVHEKHGKVDYSQGEDSPQFRHRLAGWYGGDRSVRFKMDNKFRPIPGAGGFQLSTSSATDLTCLNASLSIFDQTSISELRRKSVQLTAYLEYLLLKDTTDETRPFRIITPSNPEERGAQLSLLLKPGLLQRVADKLQSASIVCDKREPGVVRVAPAPLYNTYSEVWQFVEQLKAAFQE
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase 2, Biosynthesis of nicotinic acid protein 5-2, L-kynurenine hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_LEPIN
Sequence: MARIAGIDLPREKRIVVGLTYIFGIGNSLSKLILKKAGIDESIRVKDLNESQEAAIRKTLEETAKVEGDLRSEIQLNIKRLMDIGCYRGLRHRRGLPVNGQRTRTNARTRKGGKKTVANKKKVTK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: LUTC2_BACMK
Sequence: MTGLIQNRESFLDNIAKELGRARKTEGVERPAWKSNVNVETLKDYSQEELLEVFKKQCTNIHTTVVETTNDRLREDIQKVIVENGGGPIILSADERFDSYGLTSLFKEELPKQNVEVNVWDPEKKEENMRIAEKANIGIAFSDYTLAESGTIVVQSHKGQGRSLHFLPTVYFAIIPRETLVPRITQAVQDMNSRVEKGEAVASCINFITGPSNSADIEMNLVVGVHGPLKAVYFIV
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein C 2.
What is the protein family that this protein belongs to?
Belongs to the LutC/YkgG family.
Protein: MOAA_BRUAB
Sequence: MRNVQDQPLVSPTEPMIDPFGRAVTYLRVSVTDRCDFRCTYCMAEHMTFLPKKDLLTLEELDRLCSVFIEKGVRKLRLTGGEPLVRKNIMHLIGNLSRHLKSGALDELTLTTNGSQLARFAGELADCGVRRINVSLDTLNPEKFRTITRWGDLSRVLEGIDAAQKAAIHVKINAVALKDFNDAEIPELIRWAHGRGMDVTLIETMPMGEIEFDRTDQYLPLSQVRADLASQFTLADIPYRTGGPARYVTISETGGRLGFITPMTYNFCESCNRVRLTCTGMLYMCLGQNDDADLRKALRESESDEHLSQAIDEAISRKPKGHDFIIDREHNRPSVARHMSLTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: YAB4_ORYSI
Sequence: MSSSSSSSAVFPLDHLAAPSPTEQLCYVHCNCCDTILAVGVPCSSLFKTVTVRCGHCANLLSVNLRGLLLPAPAPAPANQLHFGPSLLSPTSPHGLLDEVAFQTPSLLMEQAASASLSSITGRSSSSCASNAPAMQMPPAKPVQQEPELPKNAPASANRPPEKRQRVPSAYNRFIKDEIQRIKAGNPDISHREAFSAAAKNWAHFPHIHFGLMPDQGFKKTFKPQDGSEDILLKDSLYAAAAAAAAAAANMGVTPF
What are the official names of this protein?
Protein YABBY 4, OsYAB7, OsYABBY4.
What is the protein family that this protein belongs to?
Belongs to the YABBY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APT_BRAHW
Sequence: MELKDYIRNIQDYPKKGILFRDITTLLQNKDAFKYAIDKMAEQISSEKIDYIVGAESRGFLIGSALAYKLNCGFIPVRKKGKLPYKTISEEYALEYGTDTLYMHEDAIKKGERVLIVDDLIATGGTALAMIKMVEKLEGIVVGSSFLIELKELNGRKEIEKYPVNVLIEY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_BIGNA
Sequence: MGLPWYRVHTVVLNDPGRLIAVHLMHTSLVSGWAGSMAFYELALFDPSDPILNPMWRQGMFVLPFMTRIGITQSWSNWSISGDSVVNPGIWSYEGVAASHIILSGLLFMAAIWHWVYWDLELFIDKRTMFPVLDLPKIFGIHLLLSGILCFGFGAFHVTGLFGPGIWVSDPYGLTGKVQQISPAWGADGFDPFNPGGVASHHIAAGILGIIAGLFHLSVRPSQRLYDALKMGNIETVLSSSIAAVFWAAFVVAGTMWYGSAATPIELFGPTRYQWDQGYFQQEIERRVQANIDNGNSIDKAWSLIPEKLAFYDYIGNNPAKGGLFRVGAMNSGDGIAVGWLGHPIFKDKLGNELFVRRMPTFFETFPVLLVDENGIVKADIPFRRAESKYSIEQVGVSATFYGGELNNATFTDPATVKKYARRAQLGEIFEFDRTTLKSDGVFRSSPRAWFTFGHLIFALLFFFGHIWHGARTLFRQVFAGIDPDLDEQIEFGTFLKLGDTSTRRQSV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FER_THAWE
Sequence: MATYKVTLISEEHDINTTIDCNDDVFVLDAAEEAGIDLPYSCRAGACSTCAGKVTEGTIDQSEQTFLDDDQMGAGFVLTCIAYPKSDCTILVHQEDELY
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FA10A_DANRE
Sequence: MAFSGTWQVYAQENYEEFLRAISLPEEVIKLAKDVKPVTEIQQNGSDFTITSKTPGKTVTNSFTIGKEAEITTMDGKKLKCIVKLDGGKLVCRTDRFSHIQEIKAGEMVETLTVGGTTMIRKSKKI
What is the function of this protein?
Binds hydrophobic ligands, such as cholate, in the cytoplasm.  May be involved in intracellular lipid transport (By similarity).  Binds one cholate per subunit.
What are the official names of this protein?
Fatty acid-binding protein 10-A, liver basic, Zf-FABP10, Zf-Lb-FABP, Fatty acid-binding protein, liver, Liver bile acid-binding protein, L-BABP, z-L-BABP, Liver-type fatty acid-binding protein, L-FABP, Liver-type FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_BRUC2
Sequence: MKETIRIIGIDPGLRRTGWGIVESLGNSLHFIGSGTVTSNAEMDLASRLCQLHEGLSKVLHEFMPHEAAVEHTFVNKDATATLKLGQARGIALLAPAQAGLPVAEYAPNAVKKAVIGVGHGEKQQIHMMVKVLMPRASFDTSDAADALAIAICHAHHRQSIVSARRMQALLAG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NDK_TREPS
Sequence: MAFETTFVMLKPGVLQRRLVGEVLSRFERKGLVLTALRLLCVDTATAELHYAEHREKPFYPSLIAYITSAPVVALAFKGENAISLVRTLCGSTRVEHAQPGTIRGDFALRTTTNIVHASDSPESAARELALYFSAQDFVEWRDGNYDFF
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBV_SINSX
Sequence: MGFVGDFCDDVARSIGFLSRIPMPARHFEGYDGRLSRAVRAFPFAGLAIALPSAAVAMALMALQVSSLFAAFVVVAIQALVTGALHEDGLGDTADGFGGGRDREAALAIMKDSRIGTYAAVALILSFGLRVSAFASILPLFSPLGAAMAILGAACLSRAAMVWHWSSLPPARSSGVAASAGEPEPAATRFALAFGLLVAMLLFYLAQVPALGVIAALVAFLATVKGFARLAMRKIGGQTGDTIGATQQLTEIAVLGALALTV
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YO83_BPP2
Sequence: MSIRIEIGERYVVTSDSFQFILHEKKRAESGKNAGQEWLAVVGYYPKLSQLVSGLMHHDILTGSAKSFADLNVQVEQLSKRCSEAFGSYGR
What are the official names of this protein?
Uncharacterized 10.2 kDa protein in GpA 5'region, ORF4.
What is the protein family that this protein belongs to?
To phage 186 CP83.
Protein: CSTN3_PONAB
Sequence: MTLLLLPLLLASLLASCSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGRIRAKEPMDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSQIYWFNGTQAVQVPLGGPSGLGSGPQDSLSDHFTLSFWMKHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVHGCRIAFLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYTDGISFDPALIHDNGLIHPPRREPALMIGACWTEGKNKEKEKGDNSTDTTQGDPLSIQRYFHGYLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILLSGTAHFARPAVDFEGTEGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPERESLLLDTTSLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQFLHRGHQPPPEMAGHSLASSHRNSMIPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWDDSALTIIVNPMESYQNRQACVTGAVGGQQEDEDSSDSEVADSPSSDERRIIETPPHRY
What is the function of this protein?
Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation.  Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with both neurexin-alpha and neurexin-beta proteins at the presynaptic membrane (By similarity).  Regulates the balance between excitatory and inhibitory synapses by inhibiting formation of excitatory parallel-fiber synapses and promoting formation of inhibitory synapses in the same neuron (By similarity).  May also be involved in ascorbate (vitamin C) uptake via its interaction with SLC23A2/SVCT2.  Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation (By similarity).
What are the official names of this protein?
Calsyntenin-3.
What is the protein family that this protein belongs to?
Belongs to the calsyntenin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Golgi apparatus membrane. Postsynapse. Cell projection, dendrite. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with both axodendritic and axospinous localization.
Protein: C82C3_ARATH
Sequence: MDTSLFSLFVSILVFVFIALFKKSKKPKYVKAPAPSGAWPIIGHLHLLGGKEQLLYRTLGKMADHYGPAMSLRLGSSETFVGSSFEVAKDCFTVNDKALASLMTAAAKHMGYVFWLEMRKIAMIELLSNRRLQMLNNVRVSEISMGVKDLYSLWVKKGGSEPVMVDLKSWLEDMIANMIMRMVAGKRYFGGGGAESSEHTEEARQWRKGIAKFFHLVGIFTVSDAFPKLGWLDLQGHEKEMKQTRRELDVILERWIENHRQQRKVSGTKHNDSDFVDVMLSLAEQGKLSHLQYDANTCIKTTCLALILGGSETSPSTLTWAISLLLNNKDMLKKVQDEIDIHVGRDRNVEDSDIKNLVYLQAIIKETLRLYPAAPLLGHREAMEDCTVAGYNVPCGTRLIVNVWKIQRDPKVYMEPNEFRPERFITGEAKDFDVRGQNFELMPFGSGRRSCPGPSLAMQMLHLGLARFLHSFEVKTVLDRPVDMSESPGLTITKATPLEVLINPRLKRELFV
What are the official names of this protein?
Cytochrome P450 82C3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SM41_HEMPU
Sequence: MKGVLFIVASLVAFATGQDCPAYYVRSQSGQSCYRYFNMRVPYRMASEFCEMVTPCGNGPAKMGALASVSSPQENMEIYQLVAGFSQDNQMENEVWLGWNSMSPFFWEDGTPAYPNGFAAFSSSGMAPPRPGAPPSRAWPVNPQNPMSGPPGRAPVMKRQNPPVRPGQGGRQIPQGVGPQWEAVEVTAMRAFVCEVPAGRNVPIGQQPGMGQGFGNQQPGFGNQPGMGGRQPGFGNQPGMGGRQPGFGNQPGMGGRQPGFGNQPGVGGRQPGFGNQPGMGGRQPGFGNQPGVGGRQPGFGNQPGMGGQQPGVGGRQPGFGNQPGMGGNQPGMGGQQPGMGGRQPGVGGRQPGMGGQQPGMGGRQPGMGGQQPNNPNNPNNPNNPNNPNNPNPRFNRPRMLQEADALA
What is the function of this protein?
Major matrix protein of the sea urchin embryo spicule which directs crystal growth in certain orientations and inhibit growth in others.
What are the official names of this protein?
41 kDa spicule matrix protein, HPSMC, HSM41.
What is the protein family that this protein belongs to?
Belongs to the SM50 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROC_MACMU
Sequence: EKWELDLDIEEVFIHPNYTKSTTDNDIALLRLAQPATLSQTIVPICLPDSGLAERELTQAGQETLVTGWGYHSSREKEAKRNRTFILNFIKIPVVPRNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGV
What is the function of this protein?
Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.  Exerts a protective effect on the endothelial cell barrier function.
What are the official names of this protein?
Vitamin K-dependent protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Endoplasmic reticulum.
Protein: IF2_STAA9
Sequence: MSKQRIYEYAKELNLKSKEIIDELKSMNIEVSNHMQALEDDQIKALDKKFKKEQKNDNKQSTQNNHQKSNNQNQNKGQQKDNKKNQQQNNKGNKGNKKNNRNNKKNNKNNKPQNQPAAPKEIPSKVTYQEGITVGEFADKLNVESSEIIKKLFLLGIVANINQSLNQETIELIADDYGVEVEEEVVINEEDLSIYFEDEKDDPEAIERPAVVTIMGHVDHGKTTLLDSIRHTKVTAGEAGGITQHIGAYQIENDGKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTIEAINHAKEAEVPIIVAVNKIDKPTSNPDRVMQELTEYGLIPEDWGGETIFVPLSALSGDGIDDLLEMIGLVAEVQELKANPKNRAVGTVIEAELDKSRGPSASLLVQNGTLNVGDAIVVGNTYGRIRAMVNDLGQRIKTAGPSTPVEITGINDVPQAGDRFVVFSDEKQARRIGESRHEASIVQQRQESKNVSLDNLFEQMKQGEMKDLNVIIKGDVQGSVEALAASLMKIDVEGVNVRIIHTAVGAINESDVTLANASNGIIIGFNVRPDSGAKRAAEAENVDMRLHRVIYNVIEEIESAMKGLLDPEFEEQVIGQAEVRQTFKVSKVGTIAGCYVTEGKITRNAGVRIIRDGIVQYEGELDTLKRFKDDAKEVAKGYECGITIENYNDLKEGDVIEAFEMVEIKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_COXBN
Sequence: MAAKVLKFSHEVLHAMSRGVEVLANAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELEDKFENMGAQMVKEVASRTSDDAGDGTTTATVLAQAILVEGIKAVIAGMNPMDLKRGIDKAVTAAVAELKKISKPCKDQKAIAQVGTISANSDKSIGDIIAEAMEKVGKEGVITVEDGSGLENALEVVEGMQFDRGYLSPYFINNQQNMSAELENPFILLVDKKISNIRELIPLLENVAKSGRPLLVIAEDIEGEALATLVVNNIRGVVKVAAVKAPGFGDRRKAMLQDIAVLTGGKVISEEVGLSLEAASLDDLGSAKRVVVTKDDTTIIDGSGDAGDIKNRVEQIRKEIENSSSDYDKEKLQERLAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALIRVLKSLDSVEVENEDQRVGVEIARRAMAYPLSQIVKNTGVQAAVVADKVLNHKDVNYGYNAATGEYGDMIEMGILDPTKVTRTALQNAASIAGLMITTECMVTEAPKKKEESMPGGGDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGTL1_VIBPA
Sequence: MSFELHSLWQERHDDEHKIRRDDHRSPYQRDRARILHSAAFRRLQAKTQVHGNSLEDFHRSRLTHSLEAAQLGTGIVAQLKKKQSEFKELLPSDSLIDSLCLAHDIGHPPYGHGGEVALNYMMRDHGGFEGNAQTFRIVTKLEPYTEHFGMNLSRRTLLGLIKYPALISQTRSVKLPNPAEHQRRLKAKEWSPAKGIYDCDKDLFDWVIAPLSENDKSLLSQMRYRPDSDLEHSKTRFKSLDCSIMELADDIAYGVHDLEDAIVLGMVTRQQWQEGAASQLADCGDPWFEEHIGSIGQMLFSGKHHQRKDAIGGMVNALLTSISIKVVDEPFQNPLLAWNACLEPHMAKALDVLKHFVSQYVIQVPQVQIVEYKGQQIIMDIFEALSADPERLLPIHTKELWQSATSDSGKMRVIADYISAMTDGHAQKLHRQLFSSIVL
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: Y12K_BPPHH
Sequence: MARLNRHPQSNIAYAVRSLRSKGQLITNSAPTQNASTDALAVNIDHRAILTVPSYRSSVRVFQRSPCLHRAEGLLSPYCNRGSERTNQGNRGSAPSKILLPRTIADPFRGGPE
What are the official names of this protein?
Uncharacterized 12.3 kDa protein in repressor 5'region.