PharMolix/UniProtQA huggingface dataset:
Protein: PTG3C_STAAM
Sequence: MRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAIQGEALQHYLPFIQNGGVQNVAKLMTAAGSIIFENLPMIFALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNVTDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDVHLGYTFSGGFIDYVLLGVLPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQSQAVTASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPFNGKIQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQLFEAK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIICBA component, EIICBA-Glc, EII-Glc, EIICBA-Glc 1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 4EBP3_HUMAN
Sequence: MSTSTSCPIPGGRDQLPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTPPTAPLSKLEELKEQETEEEIPDDAQFEMDI
What is the function of this protein?
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation.  In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-binding protein 3, 4E-BP3, eIF4E-binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the eIF4E-binding protein family.
Protein: PM2P3_HUMAN
Sequence: MNTLQGPVSFKDVAVDFTQEEWRQLDPDEKIAYGDVMLENYSHLVSVGYDYHQAKHHHGVEVKEVEQGEEPWIMEGEFPCQHSPEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCGVEEENFEGLISFSSETSHM
What are the official names of this protein?
Putative postmeiotic segregation increased 2-like protein 3, PMS2-related protein 3, Postmeiotic segregation increased 2-like protein 9, Postmeiotic segregation increased protein 5, Putative postmeiotic segregation increased 2 pseudogene 3.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: CCKN_STRCA
Sequence: MYSGICICVFLAVLSASSFGQQTAGSHNGNPLAAELEQSLTEHHRHVRAPSSAGPLKPVPRLDGSIDQRANIGALLAKYLQQARKGPTGRISVMGNRVQSIDPTHRINDRDYMGWMDFGRRSAEEYEYSS
What is the function of this protein?
This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut.  Its function in the brain is not clear (By similarity).
What are the official names of this protein?
Cholecystokinin, CCK.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEXA_SHESR
Sequence: MRPLTPRQAEILELIKRNIAETGMPPTRAEIATRLGFKSANAAEEHLKALAKKGCIEIMPGTSRGIRLPVEEEDNSETGLPLIGQVAAGEPILAQEHVEQYYQVDPSMFHPSADFLLRVKGDSMKNIGILEGDLLAVHKVQQARNGQVVVARVDDDVTVKRFEKKGNLVYLHAENEDYSPIKVDLSFQSLTIEGLAVGVIRNGDWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: HRCA_TRIV2
Sequence: MQVQLTNRQQHILWATVRHYIATAEPVGSKALVEEYDLGVSSATIRNVMGVLEKSGLLYQPHTSAGRVPSDSGYRIYVDQLITPSLRDTTRTEVLAKEVESALQQHLQWEDWSLEILLQGAAQILASLSGCISLITMPQTNTASVRHLQLVQIETGRIMLILVTDSYETHSKLMDLPPARSETKPDPEVIDRELQIVSNFLNSHLRGRSLLEISTLDWSQLDREFQSYGEFLKNSVAELAHRSAAPAATQIMVRGLAEVLRQPEFSQLQQVKTIIQLLEEEQEQLWRLIFEEPELEDTHKSKVTVRIGAENPLEPIRTCSLISSTYRRGGVPLGSVGVLGPTRLDYESAIAVVAAAADYLSEAFS
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: SERP1_PONAB
Sequence: MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPGEKASVGPWLLALFIFVVCGSAIFQIIQSIRMGM
What is the function of this protein?
Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum.  Protects unfolded target proteins against degradation during ER stress.  May facilitate glycosylation of target proteins after termination of ER stress.  May modulate the use of N-glycosylation sites on target proteins (By similarity).
What are the official names of this protein?
Stress-associated endoplasmic reticulum protein 1, Ribosome-attached membrane protein 4.
What is the protein family that this protein belongs to?
Belongs to the RAMP4 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: RBL_PINKR
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEESQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPSYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAINKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVMPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREAAKWSAELAAACEIWKEIKFEFDAIDRL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PIMT_ROSCS
Sequence: MDFTNERRAMIDLLIRRGISDQRVLDAMAQTPRHVFVPAHERSHAYSDQALPIGEGQTISQPYMVALMIEALQLAPTDRVLEIGAGSGYAAAVLSRIVAKVHTIECREALAASAAALLRTLGYDNVTVHVGDGTQGLPDYAPFDAILVSAASPWVPAPLREQLASSGRLVIPVGGRQAQILLRLRRTGDTLRTERLCDVRFVPLIGGHAWTTEHYPER
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANK_VIBCH
Sequence: MRTLAIDIGGTKIALAIVEEGTIIQRYQIATPVVQDVTKFVQAILEKVTEWLPSIDYVGVSTTGYVTPEGITSINPETLNFPVPFPLAQTLEQLTNKPVSILNDAQAAAWFEFVQLKNPSLNMAFITVSTGVGGGIIIDGKLHKGNSGLAGHIGHMSVAIEGPLCGCGQRGCVESMASGNAIQKESEATFTETMSNVELFKQAAFNPKAEAIINRSVQAVATLCCNLKACLDLDIIVLGGGIGLAEGYLERLNKAIQSRPSVFHIPVTPAHGDYDACLLGAAFQFKE
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: IF1_BUCCC
Sequence: MKEKNIEMQGTVIDTLPNTTFKVELENKHIVIAHISGKMRKNYIRILTGDKVTLELTPYDLSKGRIIFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XRN1_HUMAN
Sequence: MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE
What is the function of this protein?
Major 5'-3' exoribonuclease involved in mRNA decay.  Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates.  The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex.  Binds to RNA and DNA (By similarity).  Plays a role in replication-dependent histone mRNA degradation.  May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
What are the official names of this protein?
5'-3' exoribonuclease 1, Strand-exchange protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Discrete foci at the inner surface of the cell membrane.
Protein: P17_ASFM2
Sequence: MDTETSPLLSHNLSTREGIKQNTQGLLAHTIARHPGITAIILGILILLVIILIIVAIVYYNRSVDCKSNMPRPPPSYSIQQSEPHHHFPVFFRKRKNSTSQQAHIPSDEQLAELVHS
What is the function of this protein?
Together with the penton and the other minor capsid proteins (M1249L, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid.  Three copies of p17 encircle each p72 capsomer in the inner capsid shell, anchoring p72 capsomers on the inner membrane.  Required for the assembly of the capsid and icosahedral morphogenesis.  Additionally, inhibits the host cGAS-STING pathway through its interaction with STING1 and subsequent interference of the recruitment of downstream components TBK1 and IKBKE.
What are the official names of this protein?
Minor capsid protein p17.
What is the protein family that this protein belongs to?
Belongs to the asfivirus minor capsid protein p17 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Note=Found in the inner envelope of the virus.
Protein: BHCD_PARDP
Sequence: MLVVAEKEIAGLMTPEAAFEAIEAVFASMARRKAYNFPVVREAIGHEDALYGFKGGFDASALVLGLKAGGYWPNNQKHNLINHQSTVFLFDPDTGRVSAAVGGNLLTALRTAAASAVSIKYLAPKGAKVLGMIGAGHQSAFQMRAAANVHRFEKVIGWNPHPEMLSRLADTAAELGLPFEAVELDRLGAEADVIVSITSSFSPLLMNEHVKGPTHIAAMGTDTKGKQELDPALVARARIFTDEVAQSVSIGECQHAIAAGLIREDQVGELGAVVAGDDPGRGDAEVTIFDGTGVGLQDLAVAQAVVELAKHKGVAQEVEI
What is the function of this protein?
Imine reductase that catalyzes the NADH-dependent reduction of iminosuccinate to L-aspartate.  Is essential for the growth of P. denitrificans in the presence of glycolate and glyoxylate since it functions in glyoxylate assimilation via the beta-hydroxyaspartate cycle (BHAC).  Thereby BhcD regenerates the amino group donor for the first step of the BHAC.
What are the official names of this protein?
Iminosuccinate reductase.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family. BhcD subfamily.
Protein: TBB1_COLGR
Sequence: MREIIHLQTGQCGNQVGTAFWQTIHGEHGLDQDGVFRGSDEQQSERLSVYFTEAAKQKYVPRAVLVDLEPATMDAIRSGPLGDFFRPDNMVYGQSGAGNNWAKGHYTEGAELVDQVLDVVRREAEACDSLQGFQITHSLGGGTGSGMGTLLIAKVREEFPDRMMATFSVLPSAKVSEVVVEPYNATLSIHQLVENSDETFCIDNEALYDICRRTLKQAHPSYGHLNHLVSRVMSGLTTGFRFPGQLNADLRKLAVNLVPFPRLHFFTVGFAPLTSSASFSNLGIAELTQQMFDPKNVMLASDFRDGRFLTCSTMFRGKVSMKQVEEQIQAIKNKNSANFVEWIPNNIQTAHCSVPPKGLDVSSTFIGNSTAIQNSFRRVGDQFSLMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAGMDDEYGEEYEDEAPAEEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CASP6_ORYSI
Sequence: MEHGEISSKAPLVAPVAAGVNRAVAVVDTFLRFIAIIGTIGSAIAMGTTNETLPFFTQFIQFEAKYSDLPSFTFFVAANAVVCTYLVLSIPLSIVHILRPRARYSRLFLVFFDTAMLALLTAGASAAAAIVYLAHKGNVRANWFSICQQFDSFCERISGSLIGSFAAMVLLVVLITLSAFALARRH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 6, OsCASP6.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: OXYR_ECOLI
Sequence: MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELGVMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVGPYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPLFDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTHFRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGSPLRSRYEQLAEAIRARMDGHFDKVLKQAV
What is the function of this protein?
Hydrogen peroxide sensor.  Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA.  OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence.  OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR.  Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto-aggregation ability.
What are the official names of this protein?
Hydrogen peroxide-inducible genes activator, Morphology and auto-aggregation control protein.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: SPEH_PERMH
Sequence: MEKTLGLHILADLYGVEFDKIDHVEDVRELLEGAVKYAGLSKLSSHFHQFYPHGATGVILLEESHISIHTWPEHGYAAIDVYTCGGKEKTFKAMEYILKVLKPKRIDEKVAERGTVPVHKEATHIEKIELETV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: FHKD_DICDI
Sequence: MDEATQRQDPIEETDAEKKVQVVPSLWGRLVSNHPESRHIDLIEHSIFFGRNPKRCQVVLHDPTVSGIHCRIFREEIPCQKYNNNNNNDGDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTKNYITKITDTSSNGTFVKGCILGKDKTTIIQNGDMVSFTSAKLISSLSFTFLDLTNPYIDEPFEEEMNKKYSIQGILGTGNFSVVKRCIRRDTGEVFAVKIIDKKKFWSQTKTRRQMESEVEILQKIKHPNIISIIDIVQSDRYFYIVLELATGGELFEKIKQKGRFSEPEAKDTFKQILEAVSYLHDLNISHRDLKPENILISAVSHGKSSVIKVTDFGLAKIIGEKEMATTLCGTPLYVAPEIIRNCLHGDGGAQVNTGYGKEVDVWSLGCILYILLSGRPPFDFDHTNNFNLKLINQGLYNFSLPVWDVVTENAKDLIKKLLNVDPTKRISTKGALSHDWFNDDDLLRCSTVIANQSPISKSPQRSHGVVQLPVVDVKSKNIPMTLNSTTTNTTSPNNNNNNNNNNNNKNNNKNIIKSLNSNSNNYNNNSVLKKTSQSPKTKSNRPKLQFEQPSPNQHNNNNNNNNNNNNNNNNNNNNNNSSGGKPAIINNNGNLYSKFMATNNDPFDCTPTSTPVKPITNSTTTSTATSMPTSNSVTMGTSSTSIPVSNSITMKSPSILALSDDGDKKRKEKESSSSENVNDVIVINSNNHNNNNNNNHNINNGISSKPPPKRLKGS
What are the official names of this protein?
Probable serine/threonine-protein kinase fhkD, Forkhead-associated kinase protein D.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHK2 subfamily.
Protein: GLND_MYCTA
Sequence: MEAESPCAASDLAVARRELLSGNHRELDPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSDLDVLLLHDGKPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAALGMLEARHIAGDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHTDLPAGSLDGAYRTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSAGRTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARDAEPEHDPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVDRHVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPVCTRLGLSPPDVRTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVMAGESLPQAEPTAPHYLSLAADHGVHVEISPRDGERIDAVIVAPDERGLVSKAAAVLALNSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSDAASLVSARAGDVQAGVPVTRTAAPPRILWLDTAAPAKLILEVRAMDRAGLLALLAGALEGAGAGIVWAKVNTFGSTAADVFCVTVPAELDARAAVEQHLLEVLGASVDVVVDEPVGD
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: CARB_LACH4
Sequence: MPKRTDIHKIMVIGSGPIIIGQAAEFDYSGTQACLALRDEGYEVVLVNSNPATIMTDTTIADKVYIEPLTVDSVSRIIRQEYPDAILPTLGGQVGLNMALALAKTGILDELHIELLGTKLASIEQAEDREKFKELCQKLGEPVPPSKTVKTVEDALAFGDEIGYPIIVRPAFTMGGTGGGICHNHDELAEIAKNGLELSPVTECLIEKSIAGYKEIEFEVMRDSSDNAMIVCCMENFDPVGIHTGDSIVFSPSQTLSDKEYQMLRDCSLKLIRALKIEGGCNVQLALDPNSLDYDVIEVNPRVSRSSALASKATGYPIAKMAAKIAIGMTLDEIKNPVTGTTYAEFEPALDYVVCKIPRFPFDKFPKADRVLGTQMKATGEVMAIGRTAEEAMQKAVQSLEIDEKDLYSAKAHKASDDEIEQKLVRPQDDRLFYLAEAFRRGYSLEDVHELTKINFYFLDVVKHMVEMEKEIEANPDDLDVLRLAKKYGFSDQTIAKLWHEYPDQVRDLRKANGIVPVYKMVDTCAAEFESTTPYFYSTYDGENESRKSGKKSVIVIGSGPIRIGQGVEFDYATVHSVKALQKMGYEAIVINSNPETVSTDFSVSDKLYFEPLTLEDVLNVCDLEQPEGVIVQFGGQTSINLAAGLERHGVKILGTTVKDLDRAEDREEFDQIIKSLHLHQPQGLTATTHEGVMKAADQLGYPVLVRPSYVLGGKAMEIVYSKDELEEYLHDHADIAEDHPILVDDYLDGRECDVDAISDGKTVLLPGIMEHIEHAGVHSGDSMAVYPPQTFSDEVEEKITDVTKKLALALNCKGIMNIQFIVRDGDVYVIEVNPRASRTVPFLSKITGIEMAQVATRVIMGESLEQQGYADGLAPEPEMISVKAPVFSFSKLADVDSYLGPEMKSTGEVMGSDHTFAKALYKAFAGAKMQLPENGNVLLTIEDRDKEKILPIAKRFARIGYRIFATKGTANFLKKNDLHVELVTKVHEDEQADDNILNELRDGKIDLVINTMGHDIEKNSDGFIIRQMAIQQNVPLLTALDTADALLKSLENRSFATDALK
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: KAE1_KLULA
Sequence: MVNLNGIPPRGKRNYYLAIGLEGSANKLGVGIIKHPVLEKHEDSDLSYECDVEILANIRDTYVTPPGEGFLPRDTARHHRNWVVRIIRKALTEAKIDDPTKIDVICFTRGPGMGAPLHCVVIAARTLSLMWDIPLVGVNHCVGHIEMGREITGAKNPVVLYVSGGNTQVIAYSEKRYRIFGETLDIAIGNCLDRFARTLKIPNAPSPGYNIEQLAKQCKNKEKLVVLPYTVKGMDLSMSGILQYIDTLAKDLFKKNLKNKLLFDSRTGEQLVTVEDLCYSLQENLFAMLVEITERAMAHVNSNQVLIVGGVGCNVRLQEMMAQMCKDRSNGQVHATDDRFCIDNGVMIAQAGLLEYRTGHFVKDLSETIVTQKFRTDEVYIAWRE
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1, tRNA threonylcarbamoyladenosine biosynthesis protein KAE1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: STAR5_HUMAN
Sequence: MDPALAAQMSEAVAEKMLQYRRDTAGWKICREGNGVSVSWRPSVEFPGNLYRGEGIVYGTLEEVWDCVKPAVGGLRVKWDENVTGFEIIQSITDTLCVSRTSTPSAAMKLISPRDFVDLVLVKRYEDGTISSNATHVEHPLCPPKPGFVRGFNHPCGCFCEPLPGEPTKTNLVTFFHTDLSGYLPQNVVDSFFPRSMTRFYANLQKAVKQFHE
What is the function of this protein?
May be involved in the intracellular transport of sterols or other lipids.  May bind cholesterol or other sterols (By similarity).
What are the official names of this protein?
StAR-related lipid transfer protein 5, START domain-containing protein 5, StARD5.