PharMolix/UniProtQA huggingface dataset:
Protein: XPT_BACTN
Sequence: MQLLKKRILQDGKCYEGGILKVDGFINHQMDPVLMKSIGVEFVRRFAATNVNKIMTIEASGIAPAIMTGYLMDLPVVFAKKKSPKTIQNALSTTVHSFTKDRDYEVVISADFLTPNDNVLFVDDFLAYGNAALGILDLIEQSGAKLVGMGFIIEKAFQNGRKILEEKGVRVESLAIIEDLSNCCIKIKDQ
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_BORA1
Sequence: MTILQEVARRRTFAIISHPDAGKTTLTEKLLLFAGAIQIAGSVKARKASRHASSDWMEIEKQRGISVASSVMQMEYRDCVINLLDTPGHQDFSEDTYRVLTAVDAALMVIDAANGVEPQTIRLLQVCRARNTPIITFINKMDREVREPLELLSEIESHLGMDAVPFSWPVGMGKSFGGVFDIRRDRMRLFRPGQERRNDDDEFIDGLSNPQIAERFGQAFEQASGEIELINEAAPAFDHAAFLAGKQTPVFFGSAINNFGVQEVLDALVDLAPQPGARQALEREVKPEEPKFTGVVFKVQANMDPAHRDRVAFVRVSSGRFERGMRLKVARTNKEMRPNNVVSFLSQRRELLDEAYAGDVIGIPNHGVLQLGDVLTEGESLRFTGLPFFAPELFQAVEVKDPLRTKQLRVGLTQLGEEGAIQVFRPEVAGGSLLLGAVGQLQFEVVAHRLKTEYGVEARMLPSRYTMARWITSENPKALRKFMDANAAHIAYDVVDAAAFLIGSSAQLRVAEELYPEVKFHAMREHGGKVFGDTL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_I68A3
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILEEESDEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHIDEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNEDGRPPLPPKQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: LIPA_KORVE
Sequence: MAPELIQIDLEPRKPAPKPSWLRAKAPMGENYHDLKKLARGMNLHTVCESAQCPNIGECWNHKTATFMLLGNLCTRRCGFCAVPKGRPEPIDFDEPRRVAEAVATLGLNFAVVTSVNRDDDNVGAAQVFAQTIEQIREQKPGCRVEVLIPDFQGNDESLRIVLAAKPEILNHNTETVPRLYRAVRSGARYERTLNLLRRAKEINPAQVTKTGVMVGLGETTEELLHVYRDLARQNVDILTIGQYLRPSKDHAPMTRYYTPEEFLFMKEEAMKMGFRHVESGPLVRSSYHAHEQANSTKQPLVTI
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPM8_RAT
Sequence: MSFEGARLSMRSRRNGTLGSTRTLYSSVSRSTDVSYSESDLVNFIQANFKKRECVFFTRDSKAMESICKCGYAQSQHIEGTQINQNEKWNYKKHTKEFPTDAFGDIQFETLGKKGKYLRLSCDTDSETLYELLTQHWHLKTPNLVISVTGGAKNFALKPRMRKIFSRLIYIAQSKGAWILTGGTHYGLMKYIGEVVRDNTISRNSEENIVAIGIAAWGMVSNRDTLIRNCDDEGHFSAQYIMDDFMRDPLYILDNNHTHLLLVDNGCHGHPTVEAKLRNQLEKYISERTSQDSNYGGKIPIVCFAQGGGRETLKAINTSVKSKIPCVVVEGSGQIADVIASLVEVEDVLTSSMVKEKLVRFLPRTVSRLPEEEIESWIKWLKEILESPHLLTVIKMEEAGDEVVSSAISYALYKAFSTNEQDKDNWNGQLKLLLEWNQLDLASDEIFTNDRRWESADLQEVMFTALIKDRPKFVRLFLENGLNLQKFLTNEVLTELFSTHFSTLVYRNLQIAKNSYNDALLTFVWKLVANFRRSFWKEDRSSREDLDVELHDASLTTRHPLQALFIWAILQNKKELSKVIWEQTKGCTLAALGASKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSSDEDLAEQLLVYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFIIPLVGCGLVSFRKKPIDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLMDFHSVPHTPELILYALVFVLFCDEVRQWYMNGVNYFTDLWNVMDTLGLFYFIAGIVFRLHSSNKSSLYSGRVIFCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAVWMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDSTTYDFSHCTFSGNESKPLCVELDEYNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGIVQENNDQVWKFQRYFLVQEYCNRLNIPFPFVVFAYFYMVVKKCFKCCCKEKNTESSACCFRNEDNETLAWEGVMKENYLVKINTKANDNAEEMRHRFRQLDTKLNDLKGLLKEIANKIK
What is the function of this protein?
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius.  Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH.  Involved in menthol sensation.  Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.  Temperature sensing is tightly linked to voltage-dependent gating.  Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves.  The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials.  Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
What are the official names of this protein?
Transient receptor potential cation channel subfamily M member 8, Cold menthol receptor 1.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM8 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft. Note=Localizes to membrane rafts but is also located in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts.
Protein: ARGA_VIBCH
Sequence: MKIRSTALVKGFRQSAPYVNAHRGKTMVVMLGGEAIADKNFPNIISDIALLHSLGVKVVLVHGARPQINQILEKNQRDTPYHKGVRITDESSLGLVMQAAGQLQHAITARLSMSLNNTPMAGTQLNVVSGNFIISQPLGIDEGVDYCHSGRIRRIDVEGINRMLDLGSIVLLGPIASSVTGECFNLLSEEVATQVAIKLKADKLIGFCPQQGIIDTKGNAIAELFPSDVERLVKSMEQECAPDDEECFSTMRFLRAALKACRAGVPRSHLVSYKEDGALIQELFSFDGIGTQIVMASAEQIRQATIDDIGGIFDLIRPLEEQGILVRRSREQLEQEIHKFTIIDKDGLVIGCSALYPYPEERMAEMACVAIHPEYRDGHRGLHLLVHSKHQAKQMGIRHLFVLTTHSTHWFREQGFNEVDVEALPMAKKSLYNYQRRSKILMLQL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGES2_MOUSE
Sequence: MAQAARLSWVLVSSRCALTEGLLTRPWQPLSAQSRAGFTRVAAGSRGAAVRKGSPRLLGAAALALGGALGLYHTVRWHQRSQDLRAERSAAQLPLSNSLQLTLYQYKTCPFCSKVRAFLDFHSLPYQVVEVNPVRRTEIKFSSYRKVPILVAQEGDSLQQLNDSSVIISALKTYLVSGQPLEEVITYYPPMKAMNDQGKEVTEFCNKYWLMLDEKEAQQMYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPAEALASFDYIVREGKFGAVEAAMAKYVGAAAMYLISKRLKSRHHLQDDVRVDLYEAANKWVTAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLEAFDDLMRHSHIQPWYLRMERAIEEAPSVHHVNPSCKD
What is the function of this protein?
Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro).  The biological function and the GSH-dependent property of PTGES2 is still under debate (By similarity).  In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA) (By similarity).  May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear (PubMed:12050152).
What are the official names of this protein?
Prostaglandin E synthase 2, GATE-binding factor 1, GBF-1, Microsomal prostaglandin E synthase 2, mPGES-2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein. Nucleus. Note=According to PubMed:12050152, some fraction may be nuclear. SUBCELLULAR LOCATION: [Prostaglandin E synthase 2 truncated form]: Cytoplasm. Note=Synthesized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form.
Protein: EF1A_EIMBO
Sequence: GTSQADVALLVVPADQGGFEGAFSKEGQTREHALLAFTLGVKQMIVGINKMDATTPDKYSETRFNEIQAEVSRYLKTVGYNPEKVPFVPISGFMGDNMVERSSNMPWYKGKILVEALDNVEPPKRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGILKPGMVVCFAPTGLQTEVKSVEMHHTQLEQAVPGDNVGFNVKNVSVKDVKRGHVASDSKNDPAKAAASFQAQVIVLHHPGQINPGYSPVVDCHTAHIACKFAVLEKRLDRRSGKALEDDPKFIKTGDAAIIKMEPSKPMCVESFIEYPPLGRFAVRDMKQTVAVGVIKGVEKKEAGGKVTKSAQKATGKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_SALPB
Sequence: MQQLQNVIETAFERRADITPANVDTVTREAVNQVISLLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIDGAESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTKIYDRETGEVHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK2_STRGG
Sequence: MHLAYPAVLAALLFCVGLYGVLARRNAILVLMSVELMLNAVNLNLVAFDVWLRDTLHSGQALTLFTIAIAAAEIGIGLAIVLAVYRNRGTSAIDRLRDTAETDAAETLPDDAGTGPSGTDAAPNGDTTTATGRPGDNAGKNKKAEATR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 2, NADH dehydrogenase I subunit K 2, NDH-1 subunit K 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: S1PR3_HUMAN
Sequence: MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
What is the function of this protein?
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P).  S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.  When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
What are the official names of this protein?
Sphingosine 1-phosphate receptor 3, S1P receptor 3, S1P3, Endothelial differentiation G-protein coupled receptor 3, Sphingosine 1-phosphate receptor Edg-3, S1P receptor Edg-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PID6_FUSVN
Sequence: MLVDTGLGLISELRARLGWAALLQIVPVTVVAYNLLWFIYTSFFSSLRKIPGPFLARISRVWEIKKAATGNIHEIVMDLHRCHGPIVRIGPNRYDFDTMEALKIIYRIGNALPKADYYIPFGLPSSPNLFDVQNPARHSAMKKQVASLYTMTALLSYEAGVDGQTIILKEQLQRFCDQKQVIDLPQFLQYYAFDVIGVITVGKSMGMMETNSDTNGACGALDAMWHYSSMMAFIPHMHAWWLRLSSLLPIDVPIKGLTEYVEQRIIQYRLKAAEFGDDDALKGENNFLAKLILMERQGTVTSTETQQAVGLNIGAGSDTTANALSSILYFLYTNPRTLRRLREELDTHVKEDPIRFQQSQSMPYLQAVIKEALRLHPGVGTQLTRVVPKGGLVIEGQFFPEGAEVGVNGWALYHNKAIFGNDASVFRPERWLETKGNLNIGGSFAFGAGSRSCIGKNISILEMSKAIPQIVRNFDIEINHGDMTWKNECWWFVKPEYKAMIKPRAA
What is the function of this protein?
Can detoxify the phytoalexin pisatin from garden pea.  Pisatin is an antimicrobial compound produced by pea in response to infection by plant pathogens.
What are the official names of this protein?
Pisatin demethylase, Cytochrome P450 57A2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: HRP1_MYCTU
Sequence: MTTARDIMNAGVTCVGEHETLTAAAQYMREHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGLDPNTATAGELARDSIYYVDANASIQEMLNVMEEHQVRRVPVISEHRLVGIVTEADIARHLPEHAIVQFVKAICSPMALAS
What is the function of this protein?
Unlike some other CBS-domain containing proteins does not seem to bind AMP.
What are the official names of this protein?
Hypoxic response protein 1, HRP1.
What are the subcellular locations of this protein?
Secreted. Note=Not seen to be associated with the cell wall.
Protein: ATPO_IPOBA
Sequence: MAMTGRARSMGFSILQKALSSAQRSNAHRSILCPTLSNSELLRNYATASASKEQKIKVPLTMYGVSGNYASALYLAAVKSNTLEKVESELYDLVEASKKSPTFSQFMRDPSVPVDTRVNAIKEICAQAKFGDTTQNFLLILAENGRLKHIDRIVKRFKELTMAHRGEVKATVTTVIPLPADEEKELKATLQEMVGQGKSVQIEQKIDPTILGGLVVEFGQKVFDMSIRTRARQMERFLREPLNF
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
What are the official names of this protein?
ATP synthase subunit O, mitochondrial, Oligomycin sensitivity conferral protein, OSCP.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: RL10_FRATO
Sequence: MALRIEDKKAIVAEVAEQVSSALSAAVADYRGLTVNQMTSLRKQARESGVYLRVVRNNLARLAIKGTEFECLADALKGPLVLALSKDEPGAAAKLFKNFQKDHNAFEVKNLAMSGELFGPEKLDDFAKLPTREEALATLLNIMQAPVTKFVRTLNEIPSQAVRVFAAVGDSK
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GXCDD_DICDI
Sequence: MQPKDYMSSSHANWENIQIDSFTSWINQHLSERGLSVKDLSVDFQDGVLLLNLLEILSGKKIARYVRSPKFLQHKIDNIMIAFNFMEKAFDIKVFGCNAKDIVDGNLKQTMGVIFLLIQKIKVNLHLDHLQEQQGETTGTTTTITSTNTTTTPTKPRFYRASMQVNAANRFSHISPNKDQSSSTVATTTTTSTSVVQPQPQPTTATPTTTTATTLTPPVASQQPVSTAPATVTPSTVIPTVTPLNTTTTTTTATSTSTNVPTATTNVPPTATTTTTGTRISPTTGVSVSTIRSKFLFEGGTGNTTGGNEKYNTYSPGSGNTSGVVGPSTSSSLNISSERVLKRTESGYLISGGLSLSGSGSGGIHEPLQRTVSLIEIKLNDHQSKFYDLKKIIFMQSVIRGYLVRSKWRNVLEKYKQHLNEYKKHFMNNKKAYRGLIRVQAIVKGKIQRKKLFKMFPLYRRNEIVKEILSTEDKYVTSLAMVTTHYLKPSEAFLSTQQVRSIFSQIEIIHRYNSLILEKLVSRNKIWYSSGQKIGDIFIEMSAFLKVYTIYVNNYNNSIQTITECMEIPKFASLLEKNRNQFGLDLSAFLIAPIQRIPRYILLLQDLLKNTKESHPDHQDLSLALKKMKDVAEYVNEKKREAENLNQVLTIQSSLTGKFNNLAEPHRRYVKKGTLISNDKIHLYFLFNDLLVKTENKIVSKIRDSARLSNNNSSDKNSKSTFHSPKEIINEGKSKYLNSYFLAGSSLVDSNPDGFTFQIIGVGDANELNSQINNQINNQNNNQNNNQNNNLNNNNDDSPILSFSPFSSSFASTITNSLSSIGNSNNVNNNNNTSSNSGFVNSSNNNINIVNSNGSSPLTNSGHGLNSSFGISSNNNNNLTMPTTSIQLEALSLNEKMTWMGELDECIFQLLEKSKSKKRSLITDADELTTVPFDISVVKDSEFSNVLEKKHSEISWRSKKFYLKNTHLYYHRYSSTESPKEPTKIKCINLILCSVKLAQVVDHPHCFQLITPSRIYFFSCEDSTVLFQWISLIRLSIKKKLESLKDENNNINNFTSIASATSPTSSSSNTTPIVVPIASHSNATGSLSASLGSSFLNQQQRSLEQQQHLNTSNSNLTPLALSSQVLYHINNFISTSTSTSASQSQSQSPSPSPSHSINQKQKIRKLSFYQSRSNTLININNDEDRLNSFPTSTLSVSCLLNNDNHGNNDFDGKSFTNNIDITTTTTTNDDNNNNTTTTQVKKGKDLSCSKELNCSISHDDNSKGSSGYGNNSCGDNINNDESNNNCAECGASDPSWVSINYGVVVCLDCSSIHKNLPEGNVKSVRSLSVAFSDIVKKQEGNIKANNKYEKNIPSGLTKPNPKDSYEIKLSWIKAKYINNNNNNNNSQNGDSTTPTPTPTSTTIHVNNDSTPTSPNLNSQSSPPPTATTTQTENVKLDNGRSSPTPTPTQTENNNNNVLTPTTTTTNTTTSTTTGSRPTTPTILNNEEEHIQGINLKDSTDTSNGKGTWSRGSSHAITERKTSFLDKPRVPVKKEHQGYLFKTSSPTSNNSSDWKKYLFVYKNDVLTYYKVSKKNKRKEKGIIDLFHSVKQESRPKQKYSFTLVTSQRLYFLASETEEEMKIWLDVLSSHTTH
What is the function of this protein?
GTPase-activating protein for Rac involved in streaming and development.
What are the official names of this protein?
Guanine exchange factor for Rac 30.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasmic vesicle, phagosome membrane; Peripheral membrane protein. Note=Accumulates in cortical regions of the cell and on phagosomes.
Protein: RHAT_YERPG
Sequence: MNNAIILGIIWHLVGAASAACFYAPFKQVKKWSWETMWSIGGLVSWLILPWTVSYLLLPDFWQYYGSFSIATLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIIGTLMTPILQGRFDVLLGTPGGRMTLLGVFVALIGVAIVSYAGLLKERAMGIQAEEFNLKKGLILAVMCGIFSAGMSFAMDAAKPMHEAASALGINSLYVALPSYVIIMGGGAIINLSYCFIRLATLKNLSVKADFSVAKPLLITNILFSALAGLMWYLQFFFYAWGHAKIPQQYDYMSWMLHMSFYVLCGGIVGLLLKEWKCSTKKPVAVLCIGCLVIILAANIVGLGMAA
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRET_SALTY
Sequence: MPQQNYLDELTPGFTPLLAIKEASRCLLCHDAPCSQACPAQTDPGKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQRGCTRSGIDKPIDIARLQRFITDFEQQTAMQIYQPGSKTRGKVAIIGAGPAGLQASVTLTHLGYDVTIYEKQPQPGGWLRHGIPAFRLPQSVLDQEIARIVEMGVNIKCNCEVGGSLSLAQLKAEYRAVLMTVGMSCGSGLPLFEQASHVEIAVDFLQRARQADGDISVPRSALIIGGGDVAMDVASTLKILGCPSVTCVAREELAEFPASEKEFTSTQALGVSIIDGFTPVAVSGNKVTFHHVRHSGELTLEAENIILAVGQHARLDTFAEIKAQHNIIDTHNYQTDDPAIFAAGDIVKGDKTVVYAVKTGKEAAQAIHHYLEEACSC
What is the function of this protein?
Involved in pyrimidine base degradation.  Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate.  It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT) (By similarity).
What are the official names of this protein?
NAD-dependent dihydropyrimidine dehydrogenase subunit PreT, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
Protein: DXR_RUTMC
Sequence: MKNITLLGATGSIGKSTLSVVDLHSDKFNIFTLSANTNWQLMLELCNKYQPNYAIMVDESSAEKLSTIITTDTQILSGTQALDKVVAHQDTDFVMAAIVGTAGMSSALCAVKAGKRIMLANKESLILAGDIFMKAVEEFNAELIPVDSEHSAIFQCLQSGRSGLNKIQLTASGGPFLHTPISKFKYITPNQACAHPNWSMGRKISVDSATMMNKGLEVIEAYYLFSLTPEQIDVVVHPQSIVHSSVYYKDGSTLSQLGKPDMRTVISYAMSYPQRINSGVTALDLTNTPALEFYQPDFEKFTCLKLAFETLNKGGNAMITMNAANEIAVEYFLNHQINFLDIPKIIDQTLSAMKHTTPNSLEEVVNNDLVAREMTREIIKQYG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RS3A2_ARATH
Sequence: MAVGKNKRISKGRKGGKKKAVDPFSKKDWYDVKAPGSFTNRNVGKTLVSRTQGTKIASEGLKHRVFEVSLADLQNDEDNAYRKIRLRAEDVQGRNVLTQFWGMDFTTDKLRSLVKKWQTLIEAHVDVKTTDGYTLRMFCIAFTKRRANQVKRTCYAQSSQIRQIRRKMSEIMVKEASSCDLKELVAKFIPEAIGREIEKATQGIYPLQNVFIRKVKILKAPKFDLGKLMEVHGDYTAEDVGVKVDRPADETMVEEPTEIIGA
What are the official names of this protein?
40S ribosomal protein S3a-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5M_CRYPA
Sequence: MYLSIIILPVLGSIVAGFFGRKLGVRGAQIITCSCVIVTTILALLAWVEVGFNNIPVTINLFRWIDSEWFNIIWGFQFDSLTVSMLLPVLIISSLVHIYSISYMSGDPHNQRFFSYLSLFTFMMIILVTGNNYLLMFVGWEGVGVCSYLLVSFWFTRIAANQSSISAFLTNRVGDCFLTIGMFAILWSLGNLDYATVFSLAPYINENIITIIGICLVIGAMAKSSQVGLHVWLPMAMEGPTPVSALIHAATMVTAGVYLLMRSSPLIEYSSTVLLICLWLGAITTVFSSLVGLFQQDIKKVIAYSTMSQLGLMVVAIGLSSYNIALFHLVNHAFYKAALFLGAGSIIHAVADNQDFRKYGGLREFLPLTYSIILIASLSLAAFPFLTGFYSKDLILESAFGQFTFSGVSVYAISTIGAIFTTLYSVKVIYLTFLANPNGSLMTVRHAHEGDIFLTLPLVILAIFSIFFGYLTKDIFIGLGSSFFVDNSLYVHPVHEILIDTEFGVPTVFKILPFIFTVLFSILAILLSEFIPGSVFNFKLSRFGYNLFGFFNQRFLIEMFYNNYITNLVLTLGSQTTKVLDKGSVELIGPFGLEKGLMNFSKSLTKLSTGVVTSYALYILLGLISFIIILYLSQISSSLIVLLIILTLFSLNFNKQ
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARGC_PSEE4
Sequence: MIKVGIVGGTGYTGVELLRLLAQHPQAEVAVITSRSEAGVAVADMYPNLRGHYDGLTFSVPDSKTLGACDVVFFATPHGVAHALAGELLAAGTKVIDLSADFRLQDAAEWGKWYGQPHGAPELLKDAVYGLPEVNREKIRQARLIAVPGCYPTATQLGFLPLLEAGLADPARLIADCKSGVSGAGRGAAVGSLFCEAGESMKAYAVKGHRHLPEISQGLRLAAGKDVGLTFVPHLTPMIRGIHATLYATVADTSVDLQALFEKRYANEPFVDVMPAGSHPETRSVRGANVCRIAVHRPQGGDLVVVLSVIDNLVKGASGQAVQNLNILFGLDERMGLAHAGLLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.