PharMolix/UniProtQA huggingface dataset:
Protein: RADA_MYCBO
Sequence: MANARSQYRCSECRHVSAKWVGRCLECGRWGTVDEVAVLSAVGGTRRRSVAPASGAVPISAVDAHRTRPCPTGIDELDRVLGGGIVPGSVTLLAGDPGVGKSTLLLEVAHRWAQSGRRALYVSGEESAGQIRLRADRIGCGTEVEEIYLAAQSDVHTVLDQIETVQPALVIVDSVQTMSTSEADGVTGGVTQVRAVTAALTAAAKANEVALILVGHVTKDGAIAGPRSLEHLVDVVLHFEGDRNGALRMVRGVKNRFGAADEVGCFLLHDNGIDGIVDPSNLFLDQRPTPVAGTAITVTLDGKRPLVGEVQALLATPCGGSPRRAVSGIHQARAAMIAAVLEKHARLAIAVNDIYLSTVGGMRLTEPSADLAVAIALASAYANLPLPTTAVMIGEVGLAGDIRRVNGMARRLSEAARQGFTIALVPPSDDPVPPGMHALRASTIVAALQYMVDIADHRGTTLATPPSHSGTGHVPLGRGT
What is the function of this protein?
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks.  Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster.  Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB.  Does not have RecA's homology-searching function.
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: LPXH_COXBN
Sequence: MRHTLFISDLHLEEETPSITAHFLYFLKHQAPKADAIYILGDFFEAWIGDDNQTPFNRKIIESLQTLARTKPTYFMRGNRDFLIGQRFAAMTGVSLLEDPSVIQLYNKPVLLMHGDSLCTLDHKHQAYRRKIMKPWVQKLMLSLPLSLRRKLAKKFREQSRRHNRTLSYGIKDVTPEEVNRVMKEQNVELLIHGHTHRPAIHDLTINGNPTKRIVLGAWHHGGSVLRYAQDGSFELQAFKIDL
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNH2_VIBPA
Sequence: MVAKAKTTKAKVELPPFEYPQGYQLIAGVDEVGRGPLVGDVVTAAVILDPNNPIEGLNDSKKLSEKKRLALLPEIKEKALAWAVGRCSPEEIDELNILQATMVAMQRAITGLKVQPDLALIDGNRCPELPMDSQAVVKGDLRVAEISAASIIAKVVRDQEMEELDKQYPQFGFAKHKGYPTKAHFEAIEQHGVISEHRKSFKPVKKALGLD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_PSEPG
Sequence: MTTLMVQGTTSDAGKSTLVTALCRWLLRQGVGVVPFKPQNMALNSAVTADGGEIGRAQAVQAQACRLAPHTDMNPVLLKPNSDTGAQVIIHGRAVTSMNAVAYHDYKATAMQAVLASHQRLSAAYPVVMVEGAGSPAEINLRAGDIANMGFAEAVDCPVILVADINRGGVFAHLVGTLELLSPSEQARVKGFVINRFRGDIALLQPGLDWLEQRTGKPVLGVLPYVTDLHLEAEDGIDVRQGAKLARVLKVIVPVLPRISNHTDFDPLRLHPQVDLQFIGPGQPIPAADLIILPGSKSVRGDLAQLRERGWDKAIERHLRYGGKLIGICGGLQMLGRQVHDPLGLEGAAGSSQGLGLLDYATVLEAEKQLRNVAGTLNLEAAAVAGYEIHAGVTSGPALERPAVQLADGRCDGAVSADGQILATYLHGLFEGSQSCAALLRWAGLEDVQAIDYEALRERDIERLADLVEKHLDTALLRQLCGVA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: TP1_LITPI
Sequence: FLPIVGKLLSGLL
What is the function of this protein?
Antimicrobial peptide with activity against Gram-positive bacterium S. aureus.
What are the official names of this protein?
Temporin-1P.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KV16_RABIT
Sequence: IVMTQTPSSKSVPVGDTVTINCQAAQSVYSNNRLSWFQQKPGQPPKGLIYYASTLASGVQQDPSRFKGSGSGTQFTLTISDVQCBBAATVYYCQGYKSSDTRAFGGGTEVVVKG
What are the official names of this protein?
Ig kappa chain V region AH80-5.
Protein: JAP1_RANJA
Sequence: FFPIGVFCKIFKTC
What is the function of this protein?
Antibacterial activity against the Gram-negative bacterium E. coli and the Gram-positive bacterium S. aureus.
What are the official names of this protein?
Japonicin-1.
What are the subcellular locations of this protein?
Secreted.
Protein: MHPB_ECOLI
Sequence: MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPELVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSGIDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGRFTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVISAAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWVAAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: TRES_THETH
Sequence: MDPLWYKDAVIYQLHVRSFFDANNDGYGDFEGLRRKLPYLEELGVNTLWLMPFFQSPLRDDGYDISDYYQILPVHGTLEDFTVDEAHGRGMKVIIELVLNHTSIDHPWFQEARKPNSPMRDWYVWSDTPEKYKGVRVIFKDFETSNWTFDPVAKAYYWHRFYWHQPDLNWDSPEVEKAIHQVMFFWADLGVDGFRLDAIPYLYEREGTSCENLPETIEAVKRLRKALEERYGPGKILLAEVNMWPEETLPYFGDGDGVHMAYNFPLMPRIFMALRREDRGPIETMLKEAEGIPETAQWALFLRNHDELTLEKVTEEEREFMYEAYAPDPKFRINLGIRRRLMPLLGGDRRRYELLTALLLTLKGTPIVYYGDEIGMGDNPFLGDRNGVRTPMQWSQDRIVAFSRAPYHALFLPPVSEGPYSYHFVNVEAQRENPHSLLSFNRRFLALRNQHAKIFGRGSLTLLPVENRRVLAYLREHEGERVLVVANLSRYTQAFDLPLEAYQGLVPVELFSQQPFPPVEGRYRLTLGPHGFALFALKPVEAVLHLPSPDWAEEPAPEEADLPRVHMPGGPEVLLVDTLVHERGREELLNALAQTLKEKSWLALKPQKVALLDALRFQKDPPLYLTLLQLENHRTLQVSLPLLWSPQRREGPGLFARTHGQPGYFYELSLDPGFYRLLLARLKEGFEGRSLRAYYRGRHPGPVPEAVDLLRPGLAAGEGVWVQLGLVQDGGLDRTERVLPRLDLPWVLRPEGGLFWERGASRRVLALTGSLPPGRPQDLFAALEVRLLESLPRLRGHAPGTPGLLPGALHETEALVRLLGVRLALLHRALGEVEGVVGGHPLLGRGLGAFLELEGEVYLVALGAEKRGTVEEDLARLAYDVERAVHLALEALEAELWAFAEEVADHLHAAFLQAYRSALPEEALEEAGWTRHMAEVAAEHLHREERPARKRIHERWQAKAGKA
What is the function of this protein?
Catalyzes the reversible interconversion of maltose and alpha,alpha-trehalose by transglucosylation.
What are the official names of this protein?
Trehalose synthase, Maltose alpha-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. TreS subfamily.
Protein: RR14_BRADI
Sequence: MAKKSLIQREKKRQKLEQKYHLIRQSLKKKIRSKVSPLSLSEKTKMREKLQSLPRNSAPTRLHRRCFLTGRPRANYRDFGLSGHVLREMVYECLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLME_COLP3
Sequence: MANKKHKASSQRWLDEHFDDEYVKKAQRLGLRSRAVFKLEEINIKDRLIKPGMKVVDLGAAPGGWSEYAVKVVGDKGQVVACDILPMDAIVGVDFLEGDFREEEVLDALLTRINGKNIDVVMSDMAANMTGNESADSARSMYLVELALDMCSQVLKPNGAFVVKVFQGAGFEDYMKATRAVFKAVKTRKPESSRARSREVYLVATGYKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_ORITI
Sequence: MFNEILKKVDWHGNMLSLSTGKIARNADGAVLASMGNTSVLCTVVFDKNTKKDIDFFPLGVYYREMAYAAGKIPGGFIKKEGKFSEYEVLVSRLIDRSIRPLFDSNFRNDTQVICTVMSYDPRYSPDILAIIGSSAALAISGIPIVKPIGAARVGIVNDEFILNPVIHDNTGVNELDLVVAATFDSVTMIEAQACEIDEEKMLAAIEFGYKSLKPVINAIEEIKSSIRKDIFEVTARPHLRYNDEILKHFSSDIKSALLLQTKNERNQQLQLIQQKVVDYFSSEANDDDAILNIEKALDDVKSKIFRDLVLQDKTRIGNRAIDEIRPIICEAGLFNTVHGSALFTRGDTQSLATITLGSSTDEQIVEQLNKCERQNFLLDYIFLPYSVGEISPLRAASRREIGHGWLAKKAIQLVIPSKDVFPYTIRIVSEITQSDGSSSMATVCSASLSLMEAGVPIKTHVAGIAMGLVLGEGNKFEILSDISGCEDHLGDMDFKVASTKNGITALQLDIKVQGINLSMIESTFRQAKIGINHILNVMNNTISCPKSELSTYAPMVQTLEIQKEKIRDVIGLGGKVIKELCKTFDVEIDISENGEVKVWGNVGENVKKAVQSIENIVFVPQIGDIFDGEVVKVIESGAFIKYVTGRDGFVHISEINDTHIKDINAHVKLGDKVKVKIIGIDHKNRVKLTLRTDKEHCKNKNEQYNDITTTTGSVKKKIKIAPKEAAVISNRKYFD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMIF_BACAN
Sequence: MGSSGSMVKPISGFLTALIQYPVPVVESRADIDKQIKQIIKTIHSTKAGYPGLELIVFPEYSTQGLNTKKWTTEEFLCTVPGPETDLFAEACKESEVYGVFSIMERNPDGGEPYNTAIIIDPQGEMILKYRKLNPWVPVEPWKAGDLGLPVCDGPGGSKLAVCICHDGMFPEVAREAAYKGANVLIRISGYSTQVSEQWMLTNRSNAWQNLMYTLSVNLAGYDGVFYYFGEGQVCNFDGTTLVQGHRNPWEIVTAEVYPELADQARLGWGLENNIYNLGSRGYVATPGGVKENPYTFVKDLAEGKYKVPWEDEIKVKDGTIYGYPVKKTIHS
What is the function of this protein?
Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.
What are the official names of this protein?
Formamidase, Formamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: Y784_TREPA
Sequence: MRIRLLFAPVSCLLLVCCADSSALRWIQQPSATRNTPTIAFFQVTFDRYNTHLLETRLHAQTLEFYHHDQTWTARDIHFTRYDGNGRASVRGHAGVLLTDCEGTVFYLGKKVDCFFPHEGLRLEGRAFRWENTRALFTSDHFSPVRISDASGAVVTGVGLCVNARTKRFVFQNGVHIDVDLDSFAKTRASRYAAPNLSP
What are the official names of this protein?
Uncharacterized protein TP_0784.
Protein: MDH_PSYA2
Sequence: MSMKQPVRVAVTGAAGNISYAMLFRIASGEMLGKDQPVILQLLEIAPALDALKGVVMELEDCAFPLLAGIVQTDDATVAFKDVDYALLVGSRPRGPGMERKDLLEANAAIFSAQGKALNDVASRDVKVLVVGNPANTNALIAQRNAPDLDPRNFTAMTRLDHNRAMAQLAGKTDSTVNDVKKMIIWGNHSSTQYPDLTASTVNGKLALDLVDRTWYEGTYIPEVQQRGAAIIKARGASSAASAANAAIAHMRTWVLGTDENDWVSMGVYSNGEYGIAKGLIYSFPCTCTNGDWSIVDGVDVSSAFSKEKMAATEQELSEERDAVAHLLP
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: Y855_RICPR
Sequence: MIKINLFMKNISDSIKLHFLTKLKIFSFKREKIVVLLGNKGVFLSTFLNNKLLDQLFIPTQGQIDLTPYKNFLSKFPKSDVYFLLDGSECKMRYDQIPILQSIVKIDPIEQFIEGYFNKEDIIAHCVYEITTKPSEIWSTLIMSCPFETPLSDIISCIIDKRSLDLKGIHFLTLELKVIINKIVQNIQNDKYNDYFQVCVYVSQTSGIKFIIKHKNNIITIRNLDYPFDKTTNYVQGIIEQEIHDFFILFKNYISNLDQRVCIILIVDDELKSLLESTNFEDRNVIFIPVDNILNKQTLEKERFIDANISRLFLEYKSFPAYNNNLKSIKKLVTIKDLTFKLYTTLLIVLLLIVCIIKYNTKQNYKDINSINEKYYATNQEYDSIKYKYPYIKNTTSLADLYVIEKLLETPVPLPFDLLERLIINLNPAFKLEEIKWELTNIDNILLISKRQLIIKLILKYHTNNLSIDESLKLLDDHMQNIKNKLSHLQIDYVIYKDKILDIFGKLVIPLSVNVVDYKT
What are the official names of this protein?
Uncharacterized protein RP855.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CLPB_HELHP
Sequence: MNLFEKLTNQMKETLDSAASLALHSSNQEISLAHIYWALLSNHQSVLNQALNKMNIDKTALELQARSEVDKLPKSSQVQKENLSISKELSSALNLAQGEAIKNGDSFIAVDMFLIANLKESTFVAIFKPLVDIAEFKKTLLSLRGESKIESQSGDDNLESLSKFGIDLTQKALENTLDPVIGRDDEINAMMQILIRKSKNNPILLGEPGVGKTAVVEGLAQRIVAKAVPTSLQNKKLIALDMSALIAGAKYRGEFEERLKNVVDEVKKAGNIILFIDEIHTIVGAGASEGSMDAANILKPALARGELHTIGATTLKEYRKYFEKDAALTRRFQPINVNEPSINEALQILRGIKPNLEAHHNVNITDAALVAAAKLSSRYITDRFLPDKAIDLIDEAAAELKMQIESEPLELSKIKKHIANLEVEKQALNMEKTNVNEARVLEIDKELENLREEKMSLEGKFEQEKSVFTRIATIKAELDSLKRESELAKRSGDYNKAAEIDYGKIPDIQAQEAALHKQWEEMQQNGTLLKNAVTQESIAGVVSRWSGIPIKKMLQSQKERILGIESELAKSVVGQDDAIKAIARAIKRNKAGLNDASRPIGSFLFLGPTGVGKTQCAKTLAEFLFDNAKSLVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGVLTEAIRRKPYSIVLFDEVEKAHPDVFNILLQVLDDGRLTDSKGVSVDFSNTIIILTSNIASDKIMEIGDKQERQKAVKEALKMYFKPEFLNRLDDVVVFNPLGLADITQIVDIMFKSLAKRALEKGINVTLSQEAREHIAQVGFDSVYGARPLKRALYEEVEDRLADLILRDEIKEGDRVNFALKNGEICTHIEKE
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_STAAW
Sequence: MDKSLFEQARPILEQIQDNGFEAYYVGGSVRDYVMGRNIHDIDITTSATPDEIESIFSHTIPVGKEHGTINVVFNDENYEVTTFRAEEDYVDHRRPSGVTFVRDLYEDLQRRDFTMNAIAMDTAYKLYDYFDGQQDINNRIIRTVGIAEERFQEDALRMIRCLRFQSQLSFDIATETFEAMRIQMADIKFLSIERIVIELTKLMRGINVEKSFNHLKSLKAFNYMPYFEHLDMNQINVTEAIDLELLIAIVSVKFDINYSLKPLKLSNRQVKDINQYIQIMNALPSIITKEQLKMFVYDYDTHLIKNVMVAADVIKANDIQGHEPLIVNLQTIDETLHRLPMHNRKDMMVNGGVLMAHLNAKSGPWLKDVLRQIEIAIVTGKVSNEETEILKWVDNHVKI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: SYA_ECOLI
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNTQIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGSTIIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ
What is the function of this protein?
Attaches Ala to transfer-messenger RNA (tmRNA, also known as 10Sa RNA, the product of the ssrA gene).  tmRNA plays a major role in rescue of stalled ribosomes via trans-translation.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TWF_ANOGA
Sequence: MSHQTGIKANAELLKFFGKCKDGKTRVLKVSIENEELRLVSHSDVKRDWEKDYDTLVRPLIEESTPCYILYRLDYKIPTGYAWLLMSWVPESATVRQKMLYASTKATLKLEFGSGHIKEELNATSKEETTLQGYQKHKVDFNTPAPLTSREEELAELRKTEVKTDFGIDTKQQTLGGINCPIADAVAQALHDMRRGGYNYLQFRIDLEEEKIHLVKADNIELTGLPAQIPTDHARYHLYIFKHHHEGNYLESVVFVYSMPGYSCSIRERMMYSSCKGPFSATIEKHGIQVAKKLEIDNGAELTEEFLHEELHPRKLNLRPQFSKPKGPPSRGAKRLTKPQAVE
What is the function of this protein?
Actin-binding protein involved in motile and morphological processes.  Inhibits actin polymerization, likely by sequestering G-actin (By similarity).
What are the official names of this protein?
Twinfilin.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Protein: OPD_BREDI
Sequence: MQTRRVVLKSAAAAGTLLGGLAGCASVAGSIGTGDRINTVRGPITISEAGFTLTHEHICGSSAGFLRAWPEFFGSRKALAEKAVRGLRRARAAGVRTIVDVSTFDIGRDVSLLAEVSRAADVHIVAATGLWFDPPLSMRLRSVEELTQFFLREIQYGIEDTGIRAGIIKVATTGKATPFQELVLKAAARASLATGVPVTTHTAASQRDGEQQAAIFESEGLSPSRVCIGHSDDTDDLSYLTALAARGYLIGLDHIPHSAIGLEDNASASALLGIRSWQTRALLIKALIDQGYMKQILVSNDWLFGFSSYVTNIMDVMDRVNPDGMAFIPLRVIPFLREKGVPQETLAGITVTNPARFLSPTLRAS
What is the function of this protein?
Has an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates.  All of the phosphate triesters found to be substrates are synthetic compounds.  The identity of any naturally occurring substrate for the enzyme is unknown.  Has no detectable activity with phosphate monoesters or diesters and no activity as an esterase or protease.  It catalyzes the hydrolysis of the insecticide paraoxon at a rate approaching the diffusion limit and thus appears to be optimally evolved for utilizing this synthetic substrate.
What are the official names of this protein?
Parathion hydrolase, Phosphotriesterase, PTE.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NRDI_ECO81
Sequence: MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCGVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: SRBS2_HUMAN
Sequence: MSYYQRPFSPSAYSLPASLNSSIVMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTPYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKGGDDSKICPSLCSYSGLNGNPSSELDYCSTYRQHLDVPRDSPRAISFKNGWQMARQNAEIWSSTEETVSPKIKSRSCDDLLNDDCDSFPDPKVKSESMGSLLCEEDSKESCPMAWGSPYVPEVRSNGRSRIRHRSARNAPGFLKMYKKMHRINRKDLMNSEVICSVKSRILQYESEQQHKDLLRAWSQCSTEEVPRDMVPTRISEFEKLIQKSKSMPNLGDDMLSPVTLEPPQNGLCPKRRFSIEYLLEEENQSGPPARGRRGCQSNALVPIHIEVTSDEQPRAHVEFSDSDQDGVVSDHSDYIHLEGSSFCSESDFDHFSFTSSESFYGSSHHHHHHHHHHHRHLISSCKGRCPASYTRFTTMLKHERARHENTEEPRRQEMDPGLSKLAFLVSPVPFRRKKNSAPKKQTEKAKCKASVFEALDSALKDICDQIKAEKKRGSLPDNSILHRLISELLPDVPERNSSLRALRRSPLHQPLHPLPPDGAIHCPPYQNDCGRMPRSASFQDVDTANSSCHHQDRGGALQDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQPARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL
What is the function of this protein?
Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton.  Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1.  May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503).  Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.
What are the official names of this protein?
Sorbin and SH3 domain-containing protein 2, Arg-binding protein 2, ArgBP2, Arg/Abl-interacting protein 2, Sorbin.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Apical cell membrane. Cell junction, focal adhesion. Cell projection, lamellipodium. Note=Found at the Z-disk sarcomeres, stress fibers, dense bodies and focal adhesion. In pancreatic acinar cells, localized preferentially to the apical membrane. Colocalized with vinculin and filamentous actin at focal adhesions and lamellipodia of pancreatic cells.
Protein: ZIPA_HAES1
Sequence: MDLNAILIILGVIALIILVAHGIWSNRCEKSQYFENSKNFTREARIREPQENQQYQTADQSQSDFQRNLLETDNDCFSSESAHNSHQPLYHYSEQSAVQSVDQIKIRLPDSEPNYVMQERFSPKHTDYASMSIEELEKSIDLDEGINSSSQHLRQELAQISGQSIADDKVNIEEHMFTESTISFVEPQTNTESQQVVEKTKSGNSSFIMLYVVASENQGFSGLQLTKTLDELGFIFGKKQIYHRHVDLSITSPVLFSVANIEQPGTFDLTNIADFYTVGIALFMQSPSYGNATANLRMMIRAAKTIAQDLDGVVVTEQQEIFDEQAERDYLARVS
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: PG170_VACCW
Sequence: MYSLVFVILMCIPFSFQTVYDDKSVCDSDNKEYMGIEVYVEATLDEPLRQTTCESKIHKYGASVSNGGLNISVDLLNCFLNFHTVGVYTNRDTVYAKFASLDPWTTEPINSMTHDDLVKLTEECIVDIYLKCEVDKTKDFMKTNGNRLKPRDFKTVPPSNVGSMIELQSDYCVNDVTTYVKIYDECGNIKQHSIPTLRDYFTTKNGQPRKILKKKFDNC
What is the function of this protein?
May interact with several cellular chemokines to interfere with chemokine-glycosaminoglycan (GAG) interactions at the cell surface to alter chemotaxis of nearby responsive cells.
What are the official names of this protein?
Protein OPG170.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG170 family.
Protein: C13AA_BACTU
Sequence: MTCQLQAQPLIPYNVLAGVPTSNTGSPIGNAGNQFDQFEQTVKELKEAWEAFQKNGSFSLAALEKGFDAAIGGGSFDYLGLVQAGLGLVGTLGAAIPGVSVAVPLISMLVGVFWPKGTNNQENLITVIDKEVQRILDEKLSDQLIKKLNADLNAFTDLVTRLEEVIIDATFENHKPVLQVSKSNYMKVDSAYFSTGGILTLGMSDFLTDTYSKLTFPLYVLGATMKLSAYHSYIQFGNTWLNKVYDLSSDEGKTMSQALARAKQHMRQDIAFYTSQALNMFTGNLPSLSSNKYAINDYNVYTRAMVLNGLDIVATWPTLYPDDYSSQIKLEKTRVIFSDMVGQSESRDGSVTIKNIFDNTDSHQHGSIGLNSISYFPDELQKAQLRMYDYNHKPYCTDCFCWPYGVILNYNKNTFRYGDNDPGLSGDVQLPAPMSVVNAQTQTAQYTDGENIWTDTGRSWLCTLRGYCTTNCFPGRGCYNNSTGYGESCNQSLPGQKIHALYPFTQTNVLGQSGKLGLLASHIPYDLSPNNTIGDKDTDSTNIVAKGIPVEKGYASSGQKVEIIREWINGANVVQLSPGQSWGMDFTNSTGGQYMVRCRYASTNDTPIFFNLVYDGGSNPIYNQMTFPATKETPAHDSVDNKILGIKGINGNYSLMNVKDSVELPSGKFHVFFTNNGSSAIYLDRLEFVPLDQPAAPTQSTQPINYPITSRLPHRSGEPPAIIWEKSGNVRGNQLTISAQGVPENSQIYLSVGGDRQILDRSNGFKLVNYSPTYSFTNIQASSSNLVDITSGTITGQVQVSNL
What is the function of this protein?
Endotoxin with nematicidal activity.
What are the official names of this protein?
Pesticidal crystal protein Cry13Aa, 88 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryXIIIA(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: RS15_HAEDU
Sequence: MSLSVEAKAKIVSEFGRDAKDTGSSEVQIALLTAQINHLQTHFATHKKDHHGRRGLLRMVSRRRKLLDYLKRTDLAKYSETIARLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.