PharMolix/UniProtQA huggingface dataset:
Protein: RAPZ_ECODH
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: MUTS_LISMF
Sequence: MTEYTPMIKQYLEIKDKYQDAFLFFRLGDFYEMFFEDALNASQILEITLTGREGGTKEKIPMCGVPYHSASGYIDTLIEKGYKVAICEQVEDPKTTKGMVKREVVQLISPGTVMDERGLKAKENNYIASLYCYEAKEYGFAYSDLSTGELKSTVIEASEDRLINELTTLSTRELIVSSSEKEVLSDVMKEQLGLTFSVHEEDTIPVENEKLVTRHMSLSEKRAIGKLLHYLKETQKRDLGHLQQAVHYETSNYMKMDYYSKRNLELAESIRGKGRQGTLLWLLDNTQTAMGGRMLKQWIDRPLIDRKKIIDRQNDVSELMAHFFERLELVENLKNVYDLERLAGRVAYGNVNARDLIQLRNSLYQIPRIRATLLSMSSESLTELANQLDPCEELTEKLEEAIMDSAPISIREGGIIKDGYNSQLDTYRDASRNGKTWIAELERKERELTGIKTMKVGFNRVFGYYIEVTRANTHLLPEGRYERKQTLTNAERYITPELKEKEKLILDAEEKSMELEYQLFSEVREMVKDYIERLQKLAKSVSEIDCLQSFADISEKNHFIRPTLSEDGSLHVKQGRHPVVEKVMGAQSYVANDCDLDENREILLITGPNMSGKSTYMRQVALTAICAQVGCFVPAEEAILPIFDQIFTRIGAADDLIAGQSTFMVEMLEARNAIVHATKDSLILFDEIGRGTATYDGMALAQAIIEYIHENVHAKTLFSTHYHELTDLEKELSGLQNIHVSAVEENGKVVFLHKIKEGPADKSYGIHVAELAELPKSLIERASRILEQLENDDKKIIIASVKQPEEVHEEVQLSMFPVEPEKKASSKETKLLKEIASMNIMQMTPMDAMNKLYELQSKIH
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: EF3_PNECA
Sequence: MPGNVVSPKVLMDLIPKLKISMQETDKNEVIKNSEQHSSVSWDPDTCENLYITLEEQIESKDTLAREQALKALLLTLDATNKRVEPYLVRLLPRVLKQVGLEKVAAVRTQASTVAEDIIKTMNPYAVKTILSHVTNSIKTSGKWMEKMCAFRLLDMLVEKAPCQMSYRLPELIPILSESMWDTRTDIKNQARKTMTSVCTLISNPDIDKFIPVLIDCIAQPEKVPETIHTLGATTFVQEVHASTLSIMVPLLYRGLNERETTIKRKSAVIIDNMCKLVEDPYIIAPFLPKLIPTLEHIKETIGDPECRSVVNRSLATLIRVGNVKEGKIPEVLNIAKPENCMETLLSILKGQELVPVSDVYLNYISCIASQLIDEKNNEVVDWDVNISPYLQPIILKADINCIIDQFRKRSISGFHSSSAESEEEEGEDLCNCEFSLAYGAKILLNRTSLNLKRGYRYGLCGPNGSGKSTLLRSIFNGQLEGFPTELKTAYVEHDIDDTESKTSVFDFIANDPSVVVKNKQEVISSLLEHSFTEDMLSIPISNLSGGWKMKLALVRAMLRQVDILLLDEPTNHLDVKNVAWLENFLTSQTHITSIIVSHDSKFLDNVVQAIIHYEHFKLKKYMGNMSKFITLVPSARSYQDISMSEIEFSFPEPGYLEGVKTKQRAICRMRDIEFQYEGTSEPQIKNVSLQVSLSSRIAVIGPNGAGKSTLIKVLCGELIPQKGEVWCHPNLRIAYVAQAAFVHLGSHENKTPSEYIQWRYRTAEDSETIDRASRQLTENDEHLMNKIFKINGTSRKIQGIHSRRKLKNSYEYECSFLVGENVGEKNERWVPLPSMNNEWLPRGELIESHSKMVAEVDMKEALKSGSFRPLVRKEIEKHCESFGLDAEIVTHSRIKGLSGGQKVKLVLAAGSWLKPHVIVLDEPTNYLDRDSLGALSKALKSFEGGVVIITHSVEFTKNLTEEVWSVQNGQMTPSGHNWVQGQGTGPRLQEQEEEDTFDALGNKIEAKKKAKKLTSSELRKKKKERMARRKKGEEVFSDEDD
What is the function of this protein?
Ribosome-dependent ATPase that functions in cytoplasmic translation elongation (By similarity).  Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis (By similarity).  Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied (By similarity).
What are the official names of this protein?
Elongation factor 3, EF-3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGI4_ACET2
Sequence: MNLGVVIKIKRKKAIIVTETGEFKAVNARNGMFLGQKILFDQQDVIENNRNGIGLAYSAAIAGMVAVFVFMFTYFGLHNFNGTFAYVDVDINPSVEFAVNRDGIVVNAEPLNDDGRKVLEELIYKDALLEDVILDLVDKSRKYGFIEDNDRKNIILISAALNSDEQEQRNDFEKKLVDNLMPELENLDVNIEMRFVIASKEQRKKAQENKVSMGKYMIYEMARRQGEKLTLESIMSETLENLLLGQDFGVIETEKTPVNTPVKSTATPTKALAAEITPTKTPEQVVMTPANTPAKPTAAPTKAPAAVAVTSAKTPERATTVPVNTPVKPTDAPTKSPATATATATRAPVKATATPAKTLKPSDTPVKTPDGEQSVKVRFYNNNTLSETGVIYMRINVINTGNAPLDLSDLKLRYYYTIDSESEQRFNCDWSSIGAHNVTGSFGKVNPSRNGADTYVEIGFTKEAGMLQPGESVELNARFSKTDNTQYNKADDYSFNSHYYEYVDWDRITAYISGILKWGREP
What is the function of this protein?
Anti-sigma factor for SigI4.  Negatively regulates SigI4 activity through direct interaction.  Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI4 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI4.
What are the official names of this protein?
Anti-sigma-I factor RsgI4.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SGF11_YEAST
Sequence: MTEETITIDSISNGILNNLLTTLIQDIVARETTQQQLLKTRYPDLRSYYFDPNGSLDINGLQKQQESSQYIHCENCGRDVSANRLAAHLQRCLSRGARR
What is the function of this protein?
Component of the transcription regulatory histone acetylation (HAT) complex SAGA.  SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8).  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  SGF11 is involved in transcriptional regulation of a subset of SAGA-regulated genes.  Within the SAGA complex, participates in a subcomplex with SUS1, SGF73 and UBP8 required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  It is required to recruit UBP8 and SUS1 into the SAGA complex.
What are the official names of this protein?
SAGA-associated factor 11, 11 kDa SAGA-associated factor.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRAM_I76AK
Sequence: MNPNQKIICISATGMTLSVVSLLIGIANLGLNIGLHYKVGDTPGVNVPNENGTNSTTTIINNNTQNNFTNITNIIQTKTEEKTFLNLTKPLCEVNSWHILSKDNAIRIGEDAHILVTREPYLSCGPQGCRMFALSQGTTLRGRHANGTIHDRSPYRALISWEMGQAPSPYNTRVECIGWSSTSCHDGKSRMSICMSGPNNNASAVVWYGGRPATEIPSWAGNILRTQESECVCHNGVCPVVMTDGPANNRAATKIIYFKEGKIQKIEELTGSAQHIEECSCYGAKSVIKCICRDNWKGANRPVITIDPEMMTHTSKYLCSKILTDTSRPNDPIDGDCDAPITGGSPDPGVKGFAFLDGDNSWLGRTISKDSRSGYEMLKVPNAETSTQSGPVSHQVIVNNQNWSGYSGAFIDYWSNKECFNPCFYVELIRGRPKESSVLWTSNSIVALCGSKERLGSWSWHDGAEIIYFK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: LFTR_SHIBS
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_STRMK
Sequence: MHLSLLKTKIHRATVTHSELNYEGSIAIDDNLLAATGIREFEQVHIWDVTNGARFSTYAIRAEAGSGVVSLNGGAARHVQVGDIIIIAAFASMTEQEADSFKPKLVYVDGKNQITHTNDTIPTQAA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1898_SHEB8
Sequence: MAFWQSKTLAQMSATEWESLCDGCGKCCLNKLIDDETEDLYYTNAACLLLDHQTAGCQHYSDRFTHVPQCTVITIDNIHELTWLPDSCAYRRLAAGRELPSWHPLLTGSKEAMHLAGMSIQGKVVDERRVKDIEDHIVLWPLKDVD
What are the official names of this protein?
UPF0260 protein Shew185_1898.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: SLU7_ASHGO
Sequence: MEENKHIPKYIRDKPWYVESGDDDADYLGHHRREPGEGAQDFSVAQQGSVISDRFVAGSAPRAGRGRGRCTNCGANHDRRDCLLRPRKQARGDGGERAFQVRDENALSFEAKRDRWYGFEGPVAPAVAAAAAEPPAAAEDAAAAVERYKLGLDARAARAGVGAPAIRPRHDRARYLDDVRGEETRYDPKSRVYRGDGAAGEAPAAPDRAGRDGSTVDHVISANPTRLELGRQTPERGARQPEGQAQSAAARASLLQRYGNSARSRR
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZSC4C_MOUSE
Sequence: MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD
What is the function of this protein?
Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency.  Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation.  Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells.
What are the official names of this protein?
Zinc finger and SCAN domain containing protein 4C.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: AROA_HELP2
Sequence: MIELDINASDKSLSHRAVIFSLLAQKPCVVRNFLMGEDCLSSLEIAQNLGAKVENTAKNSFKITPPTAIKEPSKILNCNNSGTSMRLYSGLLSAQKGLFVLSGDNSLNSRPMKRIIEPLKAFEARILGREDNHFAPLVIVGSPLKACNYESPIASAQVKSAFILSALQAQGSSTYKENELSRNHTEIMLKSLGADIQDQNGVLMVSPLEKPLEAFDFTIANDPSSAFFFALACAITPKSRLLLKNVLLNPTRIGAFEALKKMGASIEYAIQSKNLEMIGDIYIEHAPLKAINIEQNIASLIDEIPALSIAMLFAKGKSMVRNAKDLRAKESDRIKAVVSNFKALGIECEEFEDGFYVEGLEDISPLKQRFSQKKPPLIKSFNDHRIAMSFAVLTLALPLEIDNLECANISFPQFKRLLNLFKKGSLNGN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALKB6_XENLA
Sequence: MQACHNFPDLDSFLVEKIPLAAYYVPEYISKSEEEYLLRQVYNAPKPKWTQLSGRKLQNWGGLPHSRGMVQEKLPSWLQKYTDQISSLGVFGDHSANHVLVNEYNAGEGIMPHEDGPMYYPTVTTISLGSHTLLDFYVPINKECQETQNQDKVASTEEQRHMLSLLLEPRSLLVVREELYTSYLHGICPRTSDTLSPMVANLGNSTAHAGDTLQRGTRVSLTIRFVPKVLKTSLLLGKGR
What is the function of this protein?
Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron.
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6, Alkylated DNA repair protein alkB homolog 6.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYS_CITK8
Sequence: MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELESLQAEIRDIALTIPNLPADDVPVGKDENDNVEVSRWGTPREFDFDVRDHVTLGEMHAGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDALPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEESMDALEEMTGHAEKVLQLLGLPYRKIVLCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_SALTO
Sequence: MTGDNLVSAYVSDAERDVEASVRPRRLAEFIAQERVRDQLDLLLQGALRRGSPPDHILLSGPPGLGKTSLANIVAAELGTSIRVTSGPAIERSGDLAAILTSLGEGDVLFIDEVHRIARPAEELLYSAMEDFRVDVVVGKGPGATAIPLDVEPFTLVGATTRAGLLTGPMRDRFGFVAHLDFYSPADLETLLNRSARILGVPITADGAAEISGRARGTPRIANRLLRRVRDFAEVRADGVVTRETAQAALTVYDVDALGLDRLDRAVLTALVDLFRGGPVGLSTLAVAVGEQPDTVEEVCEPFLVRAGLLARTPRGRVATEAAWHHLGRTPANGTFGPDVPPARDLFSVEPDQP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PDH1_SCHPO
Sequence: MNHFSKFSVTKRLLILEVLFSAISFGISIYIKVFGRSSIVTFFLLCFHLVPNALFLFPWTIITTSFVDANVFTLLSSILILSVYGVEIERSWGHKEYLLFCQFLTVIPNIAVLIPCFIAYKITDSHYLLVAIIQSTTAIQAGILTAWYQLYSCKKEESSNKFLCPLSKYLIYLFLSIHLFYVFQSFPWTYFCLAVSGTCISELYVLFVHPVVQELFHLESHTQLPI
What are the official names of this protein?
Protein pdh1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1533_PSEAE
Sequence: MMKGGMAGLMKQAQQMQEKMQKMQEELANAEVTGQSGAGLVSVVMTGRHDVKRVSLDDSLMQEDKEILEDLIAAAVNDAVRKIEQNNQEKMSGFTSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PA1533.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYP_RICAE
Sequence: MLLSKYFLPVLKEEPSEAQVTSHKLMLRSGMIRQQAAGIYTWLPLGLKVLKNIENIVRLNMNKAGALEVLMPCIQPAHLWMESGRFDNYGKEMLKFQDRHDNTLLFGPTNEDMITDIFRHNIKSYKDLPKNLYHIQWKFRDEIRPRFGVMRGREFLMKDAYSFDINEENAVKTYNQMYKAYINAFRDLGVFVIPVIADNGPIGGNLSHEFHIIAETGESTIYYDKKFKTLKDNPDIDVEEIKSWYAAAEEKYEVNKLPISEQEITSSKGIEVGHIFYIGSKYSVNMNALINDEYGKLTPIEMSSYGIGISRLVAAIIEANCDEKGIIWPSSVAPFKVSLINLNIHDSKCVELAEMAYKELSDKNIEVLYDDTEARPGSKFATHDLIGSPHQIIIGPKKAANNIVELKDRKSGVIEDIEVGSLMSVL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y065_ALLVD
Sequence: MNTTDSLKTVNEWTNKSVERMTSFGELNVRLFEKLAARQMDAVNLYMDHSMRLMKLATESKGYNDLFKGQVDATKELSERVMAESKATMQFFGDARDEYRVWFEKSLNDVSEDLRKSVAV
What are the official names of this protein?
Uncharacterized protein Alvin_0065, ORF5.
Protein: CILA_LEUMC
Sequence: MKNKVNIDVPDAILEQLDDSVFESTNYGNPEIQRVGPKVRATTGESKVQSSIDDVLSNTLKDGMTISFHHHFREGDFVFNKVMRKIIDMGYQNLTLAPSSLTNVMNDIVIEAIKKGVVTNITSSGMRGTLGDAVSHGILKNPVIFRSHGARARAIESGEIKIDVAFLGVPNSDEMGNANGMNGDAAFGSLGYALIDAQYADKLVLITDTIMPYPNTPASIKQTQVDYVVKVDKVGDPDKIGSGATRFTKDPKELKIAKTVNDVIVNSKYFKNDFSFQTGSGGAALAVTRFLREAMMAQNIMASFALGGITKPTVDLLNEGLVNRVMDVQDFDKGAASSMKLSPNQQEIDASWYADPANKGAMVDKLDVAILSALEVDTNFNVNVMSGSDGVIRGAIGGHQDAATAKLTIISVPLVRGRIATIVPKVNTVITPGDSIDVVVTEVGIAINPKRTDLVEQLKQVPGLPIYSIEELQQKAEKIVGQPAPLKFTDRVVAVAEYRDGSVIDIIKEVAD
What is the function of this protein?
Represents a citrate:acetyl-ACP transferase.
What are the official names of this protein?
Citrate lyase alpha chain, Citrase alpha chain, Citrate (pro-3S)-lyase alpha chain, Citrate CoA-transferase subunit.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNUC_ANAPZ
Sequence: MYSGQHIKEPVTRVAGLQKSVLPMLVVDSITLFYGNRKVIDNVSFSIRPGEIITILGPNGGGKTSLVRVLVGINQDYIGTIHYTKRPIIAYMPQNFKVNSFMPMTVEYLLLSACWGRGISLDLRAVIQYVDISKLLTRQISELSAGEIQLVLLARCMVMKPDLIVLDEPVSCMDVEAKNNFYRLIGKLVSKYNISIIMTSHDLHCVMACSDRVICINRSIRCEGTPEEITESAKFMSVFPENV
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEUD_BUCTS
Sequence: MNIPPIYTGSIVPLDISNIDTDAIIPKEFLQKVTKTGFGKHLFNNWRYTDHNNKILNPDFNLNKPCYRESTILLTRDNFGCGSSREHAVWALLDYGIKIIISSSFSDIFYTNSFNNQLLLITLDKTTIDLFFNLIKKNKINEITVDLIENYVFFEKKRYYFYLSNFHRMCILNGLDEIDFTLQHYKKIKKYGNQIPNFFVYNSIS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: FMT_MARN8
Sequence: MRIVFAGTPDFAATALKTLLNAGYDIVGVYTQPDRPAGRGRKLMPSPVKQVALDTGIPVYQPVSLKPEEAQQELASLQPDVMIVAAYGLILPKAVLNIPTHGCLNIHASLLPRWRGAAPIQRAIAAGDAETGITIMQMDEGLDTGDMLLKLDTPISADDTGGSLHDRLAEMGGKAIVQAMERLAKGDLTGEVQNEAEANYAHKLSKEEGHIDWSRSAQEIERLIRAFNPWPGTFTDLGEQRIRIHQASALKQGSDKGPGTVIARERDGVDVACGTGTLRITSAQLPGSKAQSINDLINGGKQVLLPGQELN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GLO2_BRADU
Sequence: MAAEIRTFSCLNDNFGYLIHDVETKATASIDAPEAGPILKALEREGWQLTDILITHHHGDHVGGVAELKHKYNCRVVAPHDKTTAIANVDLRVANADVVKVGNLLARVVETPGHTLDHISYVFDTEKTVFAADTLFSIGCGRVFEGTYPMMWDSLLKLRALPDDFKLYCGHEYTASNVKFALTVDPDNAALQARAAEVAKLRAENKPTIPSLLGDEKRANVFLRADDPSVAARLHMKGADAAAVFGELRERKNKS
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: PLSY_BACVZ
Sequence: MLIALLIILAYVIGSIPSGLIVGKLAKGIDIREHGSGNLGATNAFRTLGVKAGSVVIAADILKGTLAAALPYLLHVPIHPLLAGVAAVIGHVFPVFAKFKGGKAVATSGGVLLFYAPLLFVTMVAVFFVFLFLTKFVSLSSMLTGIYTIIYCLFVKDPYLLVVVTLLTAFVIYRHRANIKRIINKTEPKIKWF
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIG1_KLULA
Sequence: MQPSFMTMNELIVFALLLTPLLAARQQSVPGLLFSYNLAPGIVKYQDKYDNAQLPQDDFLKVAKDLISQCHSETYVFVNQPGLSRSDFKQHKQSMHKLYNYVLTSSTTVKFEKIDIVQNDDIYEELIAYTMDKCNIDDKIDIGGNVTDRYQPFVEARTRVLRVDFPPLPQQGQYVEGIGTRKDVLQANDEYLRYVMGTLPTPKHTVFYMSLEKSEVPDTETSLSYDIWPEIFTNPQRKVEIDRNDRVAKEMPKLVPYRPRIDTEDDKYLTVLDQEFIDNHYGIIVLIIGVTIAFILLQLGAVKVKKPSKPQITKDVTKEKKTQ
What is the function of this protein?
Required for normal beta-1,6-glucan synthesis.
What are the official names of this protein?
Protein BIG1.
What is the protein family that this protein belongs to?
Belongs to the BIG1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.