PharMolix/UniProtQA huggingface dataset:
Protein: FER_NEOYE
Sequence: MADYKIHLLCEEEGIDVTFNCAEDTYILDAAEEEGIELPYSCRAGACSTCAGKVTEGTVDQADQSFLDDDQLLAGYVLTCIAYPSSDCTISTHVEQELY
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: G6PT1_HUMAN
Sequence: MAAQGYGYYRTVIFSAMFGGYSLYYFNRKTFSFVMPSLVEEIPLDKDDLGFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFAWSSTVPVFAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLGPILATILAQSYSWRSTLALSGALCVVVSFLCLLLIHNEPADVGLRNLDPMPSEGKKGSLKEESTLQELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQEKGQSALVGSSYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPRHGLLLFMMAGMTVSMYLFRVTVTSDSPKLWILVLGAVFGFSSYGPIALFGVIANESAPPNLCGTSHAIVGLMANVGGFLAGLPFSTIAKHYSWSTAFWVAEVICAASTAAFFLLRNIRTKMGRVSKKAE
What is the function of this protein?
Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum.  Transports cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction (PubMed:33964207).  Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis.  Hence, it plays a central role in homeostatic regulation of blood glucose levels.
What are the official names of this protein?
Glucose-6-phosphate exchanger SLC37A4, Glucose-5-phosphate transporter, Glucose-6-phosphate translocase, Solute carrier family 37 member 4, Transformation-related gene 19 protein, TRG-19.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
Protein: EX7S_STAAC
Sequence: MTKETQSFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSAACDTTLKNAEKKVNDLIKEEAEDVKNDESTDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANXA2_RAT
Sequence: MSTVHEILCKLSLEGDHSTPPSAYGSVKPYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELPSAMKSALSGHLETVMLGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGEFRKLLVALAKGKRAEDGSVIDYELIDQDARELYDAGVKRKGTDVPKWISIMTERSVCHLQKVFERYKSYSPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKSLYYFIQQDTKGDYQKALLYLCGGDD
What is the function of this protein?
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids.  It binds two calcium ions with high affinity.  May be involved in heat-stress response.  Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
What are the official names of this protein?
Annexin A2, Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome. Note=In the lamina beneath the plasma membrane.
Protein: RS16_AFIC5
Sequence: MSVVIRLARAGTKKRPVYHVVVADSRFPRDGRFIERLGYFNPLLPKDNEARLKLDMDKVKAWLAKGAQPSDRVMRFLDAAGVAKRAPRNNPEKAVPRKERKAAAEAAAKA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TPIS_STRPN
Sequence: MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAPALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVAASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASLEAESFLALLDFVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_CAMLR
Sequence: MLNSQSGNRLRIDFSNVPQQIDIPNLLQLQKKSFDYFLNIDAKNSESGIEKVFKSIFPIHDPQNRLSLEYVSSEVGKPKYTIRECMERGLTYSVNLKMKIRLTLHEKDEKTGEKIGIKDIKEQEIYIREIPLMTDRISFIINGVERVVVNQLHRSPGVIFKEEESSTVANKLVYTAQIIPDRGSWLYFEYDAKDVLYVRINKRRKVPITILFRALGYKKQDIIKLFYPIQTIHVKKDKFLTEFNPNDFLDRVEYDLKDEKGNIIHQAGKRMTKKKAEQLVKDGIKWVEYPVEILTNRYLANPIINKETGEVLFDSLTLLDESKLAKIKEQKTFDIANDLANGVDAAIINSFIQDNETLKLLKQTENIDDENDLAAIRIYKVMRPGEPVVKDAAKAFVNDLFFNPERYDLTKVGRMKMNHKLGLDTPEYVTVLTNEDIVKTAKYLIKVKNGRGHIDDRDHLGNRRIRSIGELLANELHVGLAKMQKAIRDKFTALNTDIDKVMPYDLINPKTITVTIMEFFTGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKERAGFEVRDVHATHYGRICPVETPEGQNIGLINTLSTYAKVNDLGFVEAPYKKVENGKVSNEIVYLTATQEEGLVIAAASTKIDEKGSIVEEFVEARQDGETILARREEVHLIDLCSGMIVGVAASLIPFLEHDDANRALMGSNMQRQAVPLLTAQAPIVGTGMEKIIARDAWEAIKAKRAGIVEKVDNKNIFILGEDENGPFIDHYKMEKNLRTNQNTTFTQHPIVKKGEFVQVGQIIADGPSMDQGELAIGKNALIAFMPWHGYNYEDAIVISEKILREDTFTSVHIYEKEVEARELKDGVEEITKDIPNVKEDDLAHLDESGIAKIGTHIKPGMILVGKVSPKGEVKPTPEERLLRAIFGEKAGHVVNKSLYATASMEGVVVDVKIFTKKGYEKDARAIKAYDEEKLNLEKEHHDRLLMMDREETLRVCSLLSKSALNSDEEINGQKYKKGAKVDIKELEKINRFALNSLVKAYSKDVQKEYEDLKNHFQNEKKKLKSEHDEKLEILEKDDILPSGVVKLVKVYIATKRKLKVGDKMAGRHGNKGIVSNIVPEVDMPYLPDGRPIDIALNPLGVPSRMNIGQILESHLGIVGMRLGDQIQEIFDKKQKDFIKQLRTKILEICSVSRLTLEKKFVESLNDEQLISYARDWARGVKFATPVFEGVTVEEFSKLFEMAKIAMDGKSELYDGRTGEKMAERVHVGCMYMLKLHHLVDEKVHARSTGPYSLVTQQPVGGKALFGGQRFGEMEVWALEAYGAAHTLREMLTIKSDDVEGRFSAYKALTKGENVPATGIPETFFVLTNELKSLALDVEIFDKDENNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PA23_BOTMT
Sequence: DLWELAKMILKETGKNPLPSYGAYGCYCGWGG
What is the function of this protein?
Snake venom phospholipase A2 that shows high myotoxic activity, slight neutrophil activation (demonstrated by activation induction of IL-1beta production), slight cytotoxicity against Jurkat (leukemia T) and SK-BR-3 (breast adenocarcinoma) tumor cell lines, and slight antiparasitic activity against promastigote forms of Leishmania amazonensis.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 BmatTX-III, svPLA2, Asp49 PLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LFTR_KLEP3
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPEQFHLSRSMKRFHQRSPYRVTLNHAFGEVIEGCASDRDEGTWITSSIVRAYHQLHELGHAHSIEVWQENTLVGGMYGVAQGALFCGESMFSRAENASKTALLVFCQAFTQSGGKLIDCQVLNNHTASLGAVDIPRRDYLDYLSVLRGYRLPELFWVPRVLFPGAQ
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCE1_WOLCO
Sequence: MASSSRFAALLLLALPALALPPSQVVPRAACATPSTVPGYNNDRLPDPFLFDDGTAVTSSADWDCRRSQIAAVVQGYEAGYLPPQPPIVSATFSSSDGTGTLTVTAGLSSDNTISFSEPITYPSGTAPAAGWPLVIAYDVLSIPVPDGIAVMVYNNDDIAQENDLSSRGVGLFYDLYGTDATASAMTAWVWGVSRIIDALETTPAANINTAKIAVTGCSRDGKGALMAGAFEPRVALTIPQESGSGGDTCWRLSKYEQDSGDVVQQATEIVTENVWFSTNFDNYVNNLSVLPYDHHELAAMVAPRPLLSYENTEYEWLSPLSAYGCMSAAHTVYEALGIPDYHGFVQVGNHSHCYFPDTLDDSLYAFFDRFLLDEDDVSTDYFTTNYQFNGTVWNASYWINWTTPQLD
What is the function of this protein?
Glucuronoyl esterase which may play a significant role in biomass degradation, as it is considered to disconnect hemicellulose from lignin through the hydrolysis of the ester bond between 4-O-methyl-D-glucuronic acid residues of glucuronoxylans and aromatic alcohols of lignin.  Can hydrolyze benzyl glucuronic acid (BnGlcA), allyl glucuronic acid (allylGlcA) and to a lower degree methyl glucuronic acid (MeGlcA) in vitro.
What are the official names of this protein?
4-O-methyl-glucuronoyl methylesterase 1, Glucuronoyl esterase 1, GE1.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 15 (CE15) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYW_NEIMA
Sequence: MSKKRVLTGVTTTGIPHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEPEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNWILTCITAKGLMNRAHAYKAAVQANAENGQEDPDFGVEMGLYSYPILMTADILMFNAHEVPVGRDQIQHVEMARDIAGRFNHRFRELFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKKPDESPLFEIYKAFSTPSETAEFTKMLADGLAWGEAKKLLAAKINAELAEPRERYNELTADPSQIEEILQAGAQKARKEARELLGKVRDAVGIRPLK
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_PLAOC
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREACKWSPELAAACEVWKEIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YAT1_SYNP1
Sequence: MSYPLHLFWHRRDLRLADNLGLYAARQHTPTVVGVFCFDPALLQGQDVAAVRVAYLLGCLQALKEAYQQRGGCLLMVQGDPRQVIPEVATTLKATAVHWHEDVEPYARERDRVVAATLNDLGIAVHRQWDQLLHPPSAVQTQQGQPYTVYTPFWRNWSALPKAAPVPPPPDFAPLEATEIASIPLPSTHDLGFDWSGELILAPGEAAAAQQLAHFSQHAIYEYGEQRNYPGRPGTALLSPALKFGVIGIRTVWAASEAALEHARSDEARASIRTWQQELAWREF
What are the official names of this protein?
Uncharacterized 31.6 kDa protein in atpI 5'region, URF1.
Protein: COAD_ACET2
Sequence: MSVFVYPGSFDPVTNGHMDIIQRAAKLCDKLVVAVLVNSSKNPVFTLEERVDLLKCAVKGIDNVEIESFSGLLIDFMRKKNSKVIIKGLRAVSDFEYELQMALLNKNLDSDIETLFMMTNINYSFLSSSSVRELARHNGNIDGLVPDCIKDKIMDKFRR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_EHRRW
Sequence: MFMKDILQSSECIEDQQNISMRPNLLDEFIGQSSVVSNLKIFIDAAYERKEPIDHILLYGPPGLGKTTLAHIIAKELKVNFRSTAGPLLSKAGDLAAILTNLQARDVLFIDEIHRLNRNIEEILYSAMEDFSLDIIVGEGCGARTLRVDIPPFTLIGATTRIGLLSNPLRDRFGIPMHLEFYSTEELTKVIKRAAKVIHTNISNNGAEEISLRSRGTPRIALRLLRRIRDFISVTKQDTITHEFADQALLRLGIDKLGLDRQDIKYLQFIYEANNPIGIDTISSALSEDTGNIEETIEPYLIKINFIQRTPRGRVITQKAISYLNEQTYNM
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: Y070_MYCPN
Sequence: MKVIKKLNLLNELTMLVCIFFFVCTISLIGIGIMYDLINRTSLSAPRRDPIFRNLNTVLIVLGVLEILLMVAQLVMSNMAANIINEVAENVEQKFAKALKWSRFLPFGLLQLYCYHKIKLVTQTDNI
What are the official names of this protein?
Uncharacterized protein MG055.2 homolog.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTRR_BOVIN
Sequence: MRRFLLLYATQRGQAKAIAEEISEKAVTYGFSADLHCISESDKYDLKTETAPLVMVVSTTGNGDPPDTARKFVKAIKDKTLPPDFLAHLRYGLLGLGDSEYTYFCNGGKVIDKRLQELGAQRFYDTGHADDCVGLELVVEPWINGLWAALEKHFLSNRGREDTSETLTMASHASRDAVTPELLHVESQVGLLKLDDSGGKAAKVLEQNAVNSNQSSTLIVDFEASLTHSVPPLSQASLNIPSLPPEYLEVHLEEALGQEESHASVSLVDPVFHVPVSKAVQLTTNDAIKTTLLIELDISKTDFSYQPGDAFNVICPNSDSEVQFLLQRLQLADRREHHVAVTIKADTRKKGAALPQHVPERCSLQFLLTWCLEIRAVPKKAFLRALADHTGDSAERRRLQELCSRQGAADYTRFVREAGACLSDLLRAFPSCQPPLGLLLEHLPKLQPRPYSCASSSLFHPGKLHFIFNIVEFLSNTTEVILRRGVCTGWLATLVESILQPYMCANHVDGKKALAPKISISPRTTNSFHLPDDPSVPIIMVGPGAGVAPFIGFLQHREKLQEQHPGGHFGATWLFFGCRHKERDYLFRDELRHFLKCGVLTHLEVSFSRDVAVGEEEGPAKYVQDSLQRHSKQVAGVLLQDSGYVYVCGDAKNMAKDVHDALVEIISRETGVEKLEAMKTLATLKEEKRYLQDIW
What is the function of this protein?
Key enzyme in methionine and folate homeostasis responsible for the reactivation of methionine synthase (MTR/MS) activity by catalyzing the reductive methylation of MTR-bound cob(II)alamin.  Cobalamin (vitamin B12) forms a complex with MTR to serve as an intermediary in methyl transfer reactions that cycles between MTR-bound methylcob(III)alamin and MTR bound-cob(I)alamin forms, and occasional oxidative escape of the cob(I)alamin intermediate during the catalytic cycle leads to the inactive cob(II)alamin species.  The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine (By similarity).  Also necessary for the utilization of methyl groups from the folate cycle, thereby affecting transgenerational epigenetic inheritance (By similarity).  Also acts as a molecular chaperone for methionine synthase by stabilizing apoMTR and incorporating methylcob(III)alamin into apoMTR to form the holoenzyme.  Also serves as an aquacob(III)alamin reductase by reducing aquacob(III)alamin to cob(II)alamin; this reduction leads to stimulation of the conversion of apoMTR and aquacob(III)alamin to MTR holoenzyme (By similarity).
What are the official names of this protein?
Methionine synthase reductase, MSR, Aquacobalamin reductase, AqCbl reductase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLR89_PLAVT
Sequence: MTSVVIVVSVAVLLGVLVITDSSWPCVFNSTAKWSLQHIESVTLERPRWSRVKKPSSSKWRHLRTILQWWQERRKQAHLLDTWQKQAMDMDECLTRYRDAKHDDICVISE
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 89.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm.
Protein: HIS2_ROSDO
Sequence: MTLDALFATILDRKTADPASSWTAQLLSKGPEKCAEKFGEEAVEAIIEAVKGDRDALTGEAADVLYHLLVMLAACDVDLKDVLAELERRQNTSGIAEKQGRFKAP
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABPH_HUMAN
Sequence: MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
What are the official names of this protein?
Fatty acid-binding protein, heart, Fatty acid-binding protein 3, Heart-type fatty acid-binding protein, H-FABP, Mammary-derived growth inhibitor, MDGI, Muscle fatty acid-binding protein, M-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAEHP_ARCFU
Sequence: MEFRIGEALIGEGFEVAHVDLIIGTKDSPAGIAFANALANLSAGHTPLLAVLRPNLITKPPAVIVPKVTVKDMHQAELIFGPAQAAVAKAVADAVEEGIIPRERADEYVVVASVFIHPNAKNKHKIYYYNYGATKLAIKRAMQNFPDVDTVLYEKDRSFHPFVGRKLTKLWDPPYLQIAIDIPDLGEVLKVLEQIPDSDHIVFEVGTPLAKRYGCEVILKLREVKPDAFYILDLKTLDVGNLEARMAADATANAVVISGLAPTSTIVKGIREAEKTGILSYVDMMNVDDPIKRLEEIQKAGVLPNVVELHRAIDSEDKEPPWMLAGKIKEKFSVLVAVAGGIRPENVEEVIAAGADIIVVGRAVTKARDVEGAVRKFMSHMKPDTDQFRIMTDF
What is the function of this protein?
Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate.
What are the official names of this protein?
Bifunctional enzyme Fae/Hps.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
Protein: GKAP1_HUMAN
Sequence: MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQCR
What is the function of this protein?
Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase.  Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane.  Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.
What are the official names of this protein?
G kinase-anchoring protein 1, cGMP-dependent protein kinase-anchoring protein of 42 kDa.
What is the protein family that this protein belongs to?
Belongs to the GKAP1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: DNAB_ECOL6
Sequence: MAGNRPFNKQQTDNRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE
What is the function of this protein?
Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.
What are the official names of this protein?
Replicative DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DnaB subfamily.
Protein: MNME_SALRD
Sequence: MSQSDTIAAIATARGRAALAVVRTSGPAAIEIVDRCFRGDALTDADSHTAHVGVLTDEAGTDIDQVVATVFRAPNSATGEHVVEVSCHGGDLAPKMALQSLLDHGARMAEPGEFTERAFLNGKMDLAQAEAVADLIDATSTKAHQASLTHLKGRYSDLLGDLREELLNLCSLVELEIDFSDEDVEFADRERLEDLLDETEEILGDLLDTYPTGEKLKDGVQVVIGGRPNAGKSTLLNALVGHDRAIVSETPGTTRDEIEAEAEIEGVLFRFVDTAGLRDTADEIEAEGVRRATESIEEADVLFYLYDLTVGLDSQEIAFLQDLADDGSDVQPVVIGNKADRAPDLPVATLDGLTSLKLSALEAREDADEVQPLLDHLTDTVAEHLSRAEASPVVMNQRHRQHLRDALDAVQQAREALDAGVSGDMLTLDLRAALQELGAITGEITNEDVLDQIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNJ1_STAES
Sequence: MKQLHSNEVGVYALGGLGEVGKNTYAVEYKDEIVIIDAGIKFPDDNLLGIDYVIPDYTYLEQNQDKIVGLFITHGHEDHIGGVPFLLKQINVPIYGGPLALGLIRNKLEEHHLLRTTELHEIDESSVIKSKHFEISFYLTTHSIPEAYGVIVDTPEGKIVHTGDFKFDFTPVGEPANIAKMAQLGHEGVLCLLSDSTNALVPDFTLSEREVGQNVDKIFRNCKGRIIFATFASNIYRVQQAVEAAIKYNRKIVTFGRSMENNIKIGMELGYIKAPPETFIEPNKINSVPKHELLILCTGSQGEPMAALSRIANGTHKQIKIIPEDTVVFSSSPIPGNTKSINRTINALYKAGADVIHSKISNIHTSGHGSQGDQQLMLRLIQPKYFLPIHGEYRMLKAHGETGVQCGVDEDNVFIFDIGDVLALTHDSARKAGRIPSGNVLVDGSGIGDIGNVVIRDRKLLSEEGLVIVVVSIDFNTNKLLSGPDIISRGFVYMRESGQLIYDAQRKIKGDVISKLNSNKDIQWHQIKSSIIETLHPYLYEKTARKPMILPVIMKVNEDK
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J 1, RNase J1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYBF_SHIFL
Sequence: MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAVRFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPLCHGERLRVDTGDSLIVKSIEVE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HybF.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family. HybF subfamily.