PharMolix/UniProtQA huggingface dataset:
Protein: VATH1_CAEEL
Sequence: MVFGENQDLIRTHFQKEADKVRAMKTNWGLFTRTRMIAQSDYDFIVTYQQAENEAERSTVLSVFKEKAVYAFVHLMSQISKDDYVRYTLTLIDDMLREDVTRTIIFEDVAVLLKRSPFSFFMGLLHRQDQYIVHITFSILTKMAVFGNIKLSGDELDYCMGSLKEAMNRGTNNDYIVTAVRCMQTLFRFDPYRVSFVNINGYDSLTHALYSTRKCGFQIQYQIIFCMWLLTFNGHAAEVALSGNLIQTISGILGNCQKEKVIRIVVSTLRNLITSNQDVYMKKQAALQMIQNRIPTKLDHLENRKFTDVDLVEDMVYLQTELKKVVQVLTSFDEYENELRQGSLHWSPAHKCEVFWNENAHRLNDNRQELLKLLVAMLEKSNDPLVLCVAAHDIGEFVRYYPRGKLKVEQLGGKEAMMRLLTVKDPNVRYHALLAAQKLMINNWKDLGLEI
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity).
What are the official names of this protein?
Probable V-type proton ATPase subunit H 1, V-ATPase subunit H 1, Vacuolar proton pump subunit H 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase H subunit family.
Protein: RS16_CUPPJ
Sequence: MVVIRLARGGSKKRPFFNIVATDSRNRRDGRFIERVGFYNPLASEGEEGLRVVADRLAYWQGVGAQLSPTVARLVKQNAAKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SULA_ECO5E
Sequence: MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: TPX_LISMO
Sequence: MTQVTFKHNPVTLVGTERKVGDKAPNFTVVNRDLEEVTLHDYDGKVRLISVVPSIDTSVCSTQTRKFNEEASNLDNTVVLTISVDLPFAQKKWCAAEGLPNAITLSDHRDLSFGEAYGVIMKELRLLARSVFVVNAVGEIVYTEVVPEGSDHPNYEAAIEAAKKA
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: NKAI2_MOUSE
Sequence: MGYCSGRCTLIFICGMQLVCVLERQIFDFLGYQWAPILANFVHIIIVILGLFGTIQYRPRYVTGYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCMVTSVTPAPDWAPEDHRYITVSGCFLDYQYIEVAHSSLQIVLALAGFIYACYVVRCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYMSK
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2, Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 2, T-cell lymphoma breakpoint-associated target protein 1.
What is the protein family that this protein belongs to?
Belongs to the NKAIN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: I1BB_CONRA
Sequence: GPSFCKANGKPCSYHADCCNCCLSGICKPSTNVILPGCSTSSFFRI
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels (By similarity).  Produces excitatory symptoms when injected intracranially into mice and is lethal at higher doses.  Exposure to frog cutaneous pectoris induces spontaneous and repetitive action potentials.  This effect is slowly reversible.  Natural peptide (with D-Phe) is active on nerve, but not on muscle.  Synthetic peptide (with L-Phe) is not active on both nerve and muscle.
What are the official names of this protein?
Iota-conotoxin-like r11b, I-superfamily conotoxin R11.14.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GPDA_STACT
Sequence: MSKVAVFGMGSFGTALANVLAQNGHDVLMWGKNKQSIDEVNQYHSNSRYLNGAQLDKSITATSNLNEAINFSDTYLIALPTKAIREVIKNIDSQLDSKKVFIHVAKGIENATFKRVSEMIEDSLSPEHNGGIGVLSGPSHAEEVVIQQPTTVAASSPDPKVSKLIQDLFMNDYLRVYTNDDLVGVELGGALKNIIAVASGIVAGMGFGDNAKAALMTRGLAEISRLGEELGADPMTFLGLGGIGDLIVTCTSTHSRNYTLGYKIGQGKTVDEALSEMNMVAEGFYTTESVYHLAKQRNIDMPITSALYGVLFKQVPLDESLKLLMGRDKKSE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_PSEU2
Sequence: MKTFTAKPETVKRDWFVVDAAGQTLGRLATEIASRLRGKHKPEYTPHVDTGDYIVVINAEQIRVTGAKTTDKIYYSHSGFPGGIKSINFEKLIAKAPERVIETAVKGMLPKNPLGRDMYRKLKVYAGAVHPHTAQQPQELKF
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MSRB_VIBVU
Sequence: MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNKDSGEYACTCCHAPLFSSVNKYDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCDSHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: THIM_CLAMS
Sequence: MSALRPSTGTITRGTPTSADLLLQLRERQPLVQCITNAVVTGFTANVLLALGAAPAMTDVPTESGPFARIASGVLINLGTPHAEQREAAVEAAHAARDAGTPWVLDPVAVGALPVRTRLAHELVALSPTIVRGNASEIIALATGGAGGRGVDATDEVEAALDAASLLARTYGTVVAVSGAVDHITDGHRLVRVHTGDAWLTKVTGGGCALGAVMTAFASTDPDPLRAAVAATSGYTIAADIAAEGARGPGSFAVGLLDALDAVTPELVAQSERLS
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: KU80_CHAGB
Sequence: MADKEATVYIVDLGESMADCHNGRDESDLDFGMRYVWDKISTTVAASRKTWTLGVVGLNTEETNNAQDSEGLEGYEHISVLQDIGPMTMTQLRELRSSIQTSHTYGGDAISGIVVALAMIELFTKKLKYNRRIILVTNGESPIDDESSEDVANRLNYSNIELIVIGVDFDDADYGFKEEDKSKGKARNEKTLRKLVEQCNNGVFGTMQQAVEELAIPRIKPVRPFKAYDGALTLGDPEKYKSALSIHVERYFKTKRAPAPPASTVVVNSEPGGASQSETLNEDTEMGDAEFSGVKHMRTYRVNDPDAPGGKRDVEFEDLAKGYQYGRTVVPFSESDFSITKLETKKSFTILGFIPFSSYNPFLNLGETGIVVAQKHNEEAELGLSALIHALHELESYAVARYVQKDGAQPQLVLLKPNPAIEDDFECLYDVPLPFAEDLRSYQFPPLDKVLTVTGNIIKEHRLLPSEDLKQAMSDFVDAMDLSGFDVDEDGKPTEYAPIDETYNPTIHRMNQAIRARAVDPDAPIKPPAEILLRFSKPPEKLIEKAKPEIEALIDAAEIKKVPAKAQGRGSRKEPVKPLSGLDIDSLLGESKRTTISLDNAVPEFKQILATAADDATIESAAKQMGQIVRKLIQDSFADLFYARAAENLRVMREELISLEVPGLYNKFLTGLKKSILSGELDGDRREMWFKHIVGGHLSLITQDESEVSEVTAEEAKALCAWSRPNITYRYFRDTA
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 2, ATP-dependent DNA helicase II subunit Ku80.
What is the protein family that this protein belongs to?
Belongs to the ku80 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: FLGH_BURVG
Sequence: MKQVRLLPSATVRAACAVAVAALAGCAQIPRDPIIQQPMTAQPPMPIAMQAPGSIFNPGFAGRPLFEDQRPRNVGDILTIVIAENINATKSSGANTNRQGNTDFNVPTAAFLGGLFAKANLSATGANKFAATGGASAANTFNGTITVTVTNVLPNGNLVVSGEKQMLINQGNEFVRFSGVVNPNTISGANSVYSTQVADARIEYSAKGYINEAETMGWLQRFFLNLAPW
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: ACTZ_HUMAN
Sequence: MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKTF
What is the function of this protein?
Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Alpha-centractin, Centractin, ARP1, Actin-RPV, Centrosome-associated actin homolog.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cell cortex.
Protein: CDX_LINSA
Sequence: PDKYRVVYTDYQRLELEKEFHYSRYITMNRKAELAKSLDLTERQIKIWFQNRRAKERKINKKKDVMVKEP
What are the official names of this protein?
Homeobox protein CDX, Caudal-type homeobox protein, LSCDX.
What is the protein family that this protein belongs to?
Belongs to the Caudal homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIO_DROME
Sequence: MSGNTHGLSWFPHFPDKFVSWGQEIHLYEVRRKDDHSQKSRLPYISVNYLANESRYQYARCVAASYHSDQPIIAVGLADGKVGICNFRDTYDSSWEYTPRQQRMCTCLAWNELDANILAIGHDRHRNDTCITIWDIERGVPKETANFFGVGESANSICWDRNHRTVIAGMSQKMIKLFDLRQSNATCQSIQTKTVQGLSVSPNGNYLCSYVDSVITLWDPRNIKSPLRQIQSSKNHLQIAWCPTRTSLLSSLQRDSSYITLYDIRSVDTDNSGEIYHVKRQISPFPARYQHSGKFSFVNCLSWHSRDFERALLLADALNILDFRLPATLHTAHSNRRKLPLLMQRPLYTPASPTSTAATPTQQQPTSSCSTNSGSSLDFSTPGGSPFNVDLLKPELFELDLVDETRQRALEDYGIKPDNKRFGELHLTPYLRNVWSTLNNVYSEDRLTGLKATLGINLGHTSEALMASSRIESQVLQWPEGINNSNKLICYRSEQRDLALQLCGWAFEQELDRFIDQLYANKEYSRAAMICVFHLKIFHACNILSSAADNMRDPSMYRITVIALSSFNADRCSSTWRNQRSSANMQIHDPHLRAVFSFLTMEKDNFDAVLKEEGVSLSDRMAFACKYLSETKLADYVAQQIQAAIDGGDLNGLLLTGESQDGIDILQSYMDTSFDVQTVALVAINYFRQELFEDKRIQYWIASYLDHLNSWGLWEKRAELDIKIESIRPSSRSSRTVFLSCNFCGKSVSNALLDEPRPRSTTTSTNRLSSCPSCRKPLPRCSLCLMHMGTMVNMSNGETPTTTPDVPGWQTKPFSKWFSWCQTCRHGGHTEHIMQWFKQNSECPVSSCNCRCFDMDGTKPNTLRDIS
What is the function of this protein?
An essential component of the GATOR subcomplex GATOR2 which functions as an activator of the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:27166823, PubMed:23723238).  The two GATOR subcomplexes, GATOR1 and GATOR2, regulate the TORC1 pathway in order to mediate metabolic homeostasis, female gametogenesis and the response to amino acid limitation and complete starvation (PubMed:27166823, PubMed:23723238).  GATOR2 activates the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex, controlling the switch to cell proliferation and growth under nutrient replete conditions and during female oocyte development (PubMed:21521741, PubMed:25512509, PubMed:14973288, PubMed:23723238).  This component is required for activating TORC1 specifically in germline cells to promote cell growth and maintain the oocyte fate (PubMed:27166823, PubMed:21521741, PubMed:23723238).  GATOR1 and GATOR2 act at different stages of oogenesis to regulate TORC1 in order to control meiotic entry and promote oocyte growth and development (PubMed:21521741, PubMed:25512509, PubMed:14973288, PubMed:23723238).  After exactly four mitotic cyst divisions, the GATOR1 complex members (Iml1, Nprl2 and Nprl3) down-regulate TORC1 to slow cellular metabolism and promote the mitotic/meiotic transition (PubMed:25512509).  At later stages of oogenesis, the mio and Nup44A components of the GATOR2 complex inhibit GATOR1 and thus activate TORC1 to promote meiotic progression, and drive oocyte growth and development (PubMed:21521741, PubMed:25512509).  In addition to its role in the regulation of the TORC1 complex, functions independently of TORC1 to prevent the inappropriate accumulation of autolysosomes in germline tissues (PubMed:27166823).
What are the official names of this protein?
GATOR complex protein MIOS, Missing oocyte protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat mio family.
What are the subcellular locations of this protein?
Nucleus. Lysosome. Note=Accumulates in pro-oocyte nuclei in early prophase of meiosis I (PubMed:14973288). In egg chambers, detected in lysosomes and autolysosomes of both fed and starved females (PubMed:25512509).
Protein: RHLB_SALA4
Sequence: MSKTHLTEQKFSDFALHPQVVEALEKKGFYNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIDDRKVNQPRALIMAPTRELAVQIHADAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPAAQRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIESYIGHSIPVSKYNPEALMNDLPKPLRLTRSRPGNGPRRAGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBC_EUGGR
Sequence: METLFNKKLTVGGRDQESTGFAWWAGNARLINVSGKLLGAHVAHAGLIVFWTGAMNLFEVAHFVPQKPMYEQGLILLPHLATLGFGVGFDGIVLDTYPFFVCGVLHLISSAVLGFGGVFHSLAGPDTLEESFRFFGYTWKRKKKLAAILGIHLCFLGLGALLLAWKAMYGGGVYDTWWPGGGDVRSITNPTLNPFIIFGYLVKSPFGGEGWIVSVDSMEYVIGGHIWIGILLVSGGFWHICSRPSPWVVRTFVWSGEAYLSYSLGAVATMGFIAVPMVWFNNTVYPSEFYGPTGPEASQAQAFTFLIRDQRLGTNIASAQGPTGLGKYLMKSPTGEIIFGGETMRFWDFRGPWLEPLRGPNGLDLNKLKNDVQPWQERRAAEYMTHAPLGSLNSVGGVATEINAVNFVNPRSWLATSHFVLAFFFFVGHLWHAGRARAAAIGFEKGIDRSREIARKLKPLD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: H16A8_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLGQADKDENRMEMQKKTEQGKSYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1a, U11-TRTX-Hhn1a, Hainantoxin-XVI.8, HNTX-XVI.8, Peptide F4-19.87.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UTP25_CLAL4
Sequence: MKRPGSNKRPAKSKDGAESRPKRANRGRQQLRTITRTARRDVDAPVEETPESSESEAEEAAPEEKKFEQGKAYDALLTLLQSEHPEKSDKKKTASRHEEDDVAGVNLEEDDDDDDEEEEEEENDEVEDDANEHGDPFEVHFGVDDEAVAAKAALLSARWPVAHKAKVGAYAVTTHASPGEKTAACEAPRAQTLGAPVKKRVADAFAARHPAPFSPLEQELAHHIFSYRDVLYASRTYDNTVHRKLYAAHVLNHVFKTRDRVLKNNDVLKNYHSAQQQGKATGPEPEPRDQGFTRPKVLILLPTRNAAYEVVEQLIGMSGAAQQENRRRFKAQFHADGGPPDSKPADFRAMFHGNSNDFFSIGLKFTRKSVKLYASFYGADILVASPIGLAMILEDPKQAKREYDFLSSIEVLVVDRANELEMQNWDHVHTVLRYINKIPKDFHGADFSRIRMWAINDHARLLRQTLVFCDFLTPSVSNVITHSQNIAGKTRFRPETTAQTCVMNSVGLRLKQIFQRFDAPDPQSSVDARFRFFVNSVLPSLSKQTSYDDGLLIYVPSYFDYVRLKAHMKTHTKLDFSAIDEYSSRAKITRARHFFSTGKTKLLLYTERLHHYRRFELAGVKNIVLYGPPENPLFYKELLRFVGKSVFKGDADTDLSFIKTIYCKWDAAALERICGAEKAAVLCNSVNEMFEFR
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACEK_COLP3
Sequence: MKDELALTIANTIINGFERHFAIFTEITQSARNRFQQCQWNEIHRSARARTNFYDERVKETFNDIKEDFNISSLDDALWQRVKAVYSDLLINHKQPELAETFYNSVFCHLFERKYYHNDYIYVESTAHRLDDKTQPEIYTSYQPKELGLKQTICDIMNSHRTVIPFEDLDRDVDALINTFRRKAHKTRVKLEDLKFDILNFTFYRNKGAYLIGRVLSPAGETPFIIAVLNNEKGGLYIDALLTSSESMAVVFGFARAYFFVDCEHPYALVNFLQGLMPHKTKADLYSAIGFHKQGKTQFYRDFLNHLDSSDDQFELAAGIKGMVMSVFTLPSYPYVFKIIKDKFSPSKNITKKDVKGKYRLVKLHDRVGRMADTMEYSEVAFPKSRFNDELLAELQKVAPSIIRYEGEGEEALIIIEHLYIERRMVPLNLYLMDALKNKAQQKIDDALFGYGQAIKQLISADIFPGDMLLKNFGVTRHGRVIFYDYDEIAYMNEINFRVKPKAVTEEQLYAAEPWYSVMPGDMFPEELATFALANPSYLKAFKIHHEDLLTAAYWQQCQQDVANGIYKDVFPYPDKYRFCNLSFGSIKR
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B_MAGO7
Sequence: MPPKAADKKPASKAPATASKAPEKKDAGKKTAASGDKKKRTKTRKETYSSYIYKVLKQVHPDTGISNRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSTK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: AUX1_ARATH
Sequence: MSEGVEAIVANDNGTDQVNGNRTGKDNEEHDGSTGSNLSNFLWHGGSVWDAWFSCASNQVAQVLLTLPYSFSQLGMLSGIVLQIFYGLLGSWTAYLISVLYVEYRARKEKEGKSFKNHVIQWFEVLDGLLGSYWKALGLAFNCTFLLFGSVIQLIACASNIYYINDHLDKRTWTYIFGACCATTVFIPSFHNYRIWSFLGLGMTTYTAWYLAIASIIHGQAEGVKHSGPTKLVLYFTGATNILYTFGGHAVTVEIMHAMWKPQKFKYIYLMATLYVFTLTIPSAAAVYWAFGDALLDHSNAFSLMPKNAWRDAAVILMLIHQFITFGFACTPLYFVWEKVIGMHDTKSICLRALARLPVVIPIWFLAIIFPFFGPINSAVGALLVSFTVYIIPSLAHMLTYRSASARQNAAEKPPFFMPSWTAMYVLNAFVVVWVLIVGFGFGGWASVTNFVRQVDTFGLFAKCYQCKPAAAAAHAPVSALHHRL
What is the function of this protein?
Carrier protein involved in proton-driven auxin influx.  Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex.  Unloads auxin from the mature phloem to deliver the hormone to the root meristem via the protophloem cell files.  Coordinated subcellular localization of AUX1 is regulated by a brefeldin A-sensitive (BFA) vesicle trafficking process.  Involved in lateral root formation, trichoblast polarization and root hair elongation.  Required for gravitropism and thigmotropism, especially in roots, by modulating responses to auxin, ethylene and cytokinins such as benzyladenine (BA).  Needed for ammonium-mediated root-growth inhibition.  Confers sensitivity to the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D, auxin analog), and to polar auxin transport inhibitors such as N-1-naphthylphthalamic acid (NPA) and 2,3,5-triiodobenzoic acid (TIBA).
What are the official names of this protein?
Auxin transporter protein 1, Auxin influx carrier protein 1, Polar auxin transport inhibitor-resistant protein 1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.1) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=In S2 columella cells, a dynamic cytoplasmic to membrane localization seems to occur during early stage of gravity signal transduction. In roots protophloem cells, asymmetric repartition in the upper plasma membrane.
Protein: OB57C_DROME
Sequence: MLKLWLICILTVSVVSIQSLSLLEETNYVSDCLASNNISQAEFQELIDRNSSEEDDLENTDRRYKCFIHCLAEKGNLLDTNGYLDVDKIDQIEPVSDELREILYDCKKIYDEEEDHCEYAFKMVTCLTESFEQSDEVTEAGKNTNKLNE
What is the function of this protein?
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
What are the official names of this protein?
General odorant-binding protein 57c.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
Protein: RIMM_ECO45
Sequence: MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLEEGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLDGQVIKKVDLTTRSIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.