PharMolix/UniProtQA huggingface dataset:
Protein: TM239_MOUSE
Sequence: MQQPRVESDIIGAGEGPQRAVPWSAWIIRQDWVRWWVCHIPRSWTQWWNTSGWRQPLQRMLWGLEGTLYLLLALMLCHALFTTGSYLLSSLWPVVAVMWSHLLPAILLLVLSALPALLFAASFLLLFSTLLSLVGLLTSMTQPGYAQDLDQ
What are the official names of this protein?
Transmembrane protein 239.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL7_SYNS9
Sequence: MSAKTDEILESLKSLSLLEASELVKQIEEAFGVSAAASAGVVMAAPGAAGGGEAAEEKTEFDVILESFEASAKIKVLKAVREATGLGLGDAKALVEAAPKLVKEGASKDDAEALKKAIEEVGGKVTIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: DBP3_YEAST
Sequence: MTKEEIADKKRKVVDEEVIEKKKSKKHKKDKKDKKEKKDKKHKKHKKEKKGEKEVEVPEKESEKKPEPTSAVASEFYVQSEALTSLPQSDIDEYFKENEIAVEDSLDLALRPLLSFDYLSLDSSIQAEISKFPKPTPIQAVAWPYLLSGKDVVGVAETGSGKTFAFGVPAISHLMNDQKKRGIQVLVISPTRELASQIYDNLIVLTDKVGMQCCCVYGGVPKDEQRIQLKKSQVVVATPGRLLDLLQEGSVDLSQVNYLVLDEADRMLEKGFEEDIKNIIRETDASKRQTLMFTATWPKEVRELASTFMNNPIKVSIGNTDQLTANKRITQIVEVVDPRGKERKLLELLKKYHSGPKKNEKVLIFALYKKEAARVERNLKYNGYNVAAIHGDLSQQQRTQALNEFKSGKSNLLLATDVAARGLDIPNVKTVINLTFPLTVEDYVHRIGRTGRAGQTGTAHTLFTEQEKHLAGGLVNVLNGANQPVPEDLIKFGTHTKKKEHSAYGSFFKDVDLTKKPKKITFD
What is the function of this protein?
ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis.  Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP3, DEAD box protein 3, Helicase CA3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: N8DT2_SOPFL
Sequence: MGFVLPASFPGASSITTGGSCLRSKQYAKNYYASSYVTTLWHKKGKIQKEYCAVIFSRHNLKQHYKVNEGGSTSKECEKKYVVNAISEQSFEYEPQARDPKNIWGSVNDALDTFYKFCRPYAIFSVVLGATFKSLVAVERLSDLSLAFFIGWLQVVVAVICIHIFDVGLNQLCDIEIDKINKPDLPLASGNLSFRNVVIITASSLILGLGFAWIVGSWPLFWTVFICCMFAAAYNVDLPLLRWKKYPVLTAISFIANVAVTRSLGFFLHMQTCVFKRPTTFPRPLIFCTAIVSIYAIVIALFKDIPDMEGDEKFGIQSLSLRLGPKRVFWICVSLLEMAYGVTILVGATSPILWSKIITVLGHAILASVLWYHAKSTDLTSNVVLQSFYMFIWKLHTAEYCLIPLFR
What is the function of this protein?
Involved in the biosynthesis of sophoraflavanone G (SFG).  Can use flavanones (naringenin, liquiritigenin and hesperetin) as substrates, but not flavonols or isoflavones.  Shows a strict specificity for dimethylallyl diphosphate.
What are the official names of this protein?
Naringenin 8-dimethylallyltransferase 2, chloroplastic, SfN8DT-2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: AMPA_BACCQ
Sequence: MFQVQKELASHEAVIVALFEEEETSSFVQELDKAFEGQLQVLLEEKELSTKKKAISKVHSLGKTEVKRYYFVGLGKKESYTTETLRSALGKTFKTLQAAKVQDAAILLDSFVTEKLDAIDVAHIAAEVQGLGTYELQTYKSDKKDRVELEKFTAITAEDAQEIEAALTVGYVHGRATNSARTLVNMPPNVLTATKLAEYAVELAEKYDMDYKVLEKEEMEELGMGALLAVNQGSVEPPKMIALIYKGKEEWTDVIGFVGKGITYDTGGYSLKPREGMVGMKGDMGGAAAVLGAMEIIGELRPEQNVIAVIPSTDNVVSGTAFKPDDVITSMSGKTIEVLNTDAEGRLALADGITYAKKLGANYLIDVATLTGGVIVALGNHTTGAMTNNEELFEQVLEASMETDESIWQLPIFDRDKERVRNSKFADLNNSPGREGHAVMAGTFLGEFAEDTPWVHLDIAGTSESSGAHDLGPAGATGAMVRTLATLVERFGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_PENEL
Sequence: MTNIRKTHPLMKIINNAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHIGRGLYYGSYMFQETWNIGVLLLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVAVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGALLLILALLTLTLFTPDLLGDPNNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILIFIPMLQTSKQRSMMFRPFSQLLFWTLIADLLTLTWIGGQPVEHPYIIVGQLASILYFLLILVLMPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS7_BURP1
Sequence: MRVAQVVRNTSETQISVKIDLDGTGRQKLATGVPFLDHMLDQIARHGLVDLDIEANGDTHIDDHHTVEDVGITLGQAVAKAVGDRKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARIGTFDVDLSIEFFRGFVNHAGVTLHIDNLRGVNAHHQLETVFKAFGRALRMAVELDERAAGQIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_PSEMY
Sequence: MDLSPREKDKLLIFTAGLVAERRLARGVKLNYPEAMAYISAALLEGARDGQTVAELMHFGTTLLSREQVMEGVPEMIPEIQIEATFPDGTKLVTVHQPIA
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMC_BUCAP
Sequence: MIFSKNSQLILRHQKIFKNKIVFFSGNIEDELPINLLTIKTKIHLQKSQNFLKINNNKNITFYRKLLVSQDTVQDCNILIYYWPKNKSEARFQLFNILSFLPIKSEIFIVGSNSSGVKSAKLILEESIKLKKIDNANHSILMSGILINKTKFKLEKFFKIHIWKNLIIKSLPGVFGHKKIDEGSKFIASTFSEKINGKILDVGCGSGFLSVSILRKSPKCVVTMIDRKLSALESSKATLDANFFKGEVLSSNIYSNIFKKFNMIVSNPPLHDDLKINFDITKKIIFNSKKHLKKNGELRFVTNHCFSYDFYLKKVFSEFHIMKKDNKYKVYQAFLK
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_EHRCJ
Sequence: MGIKNLNSVTASLRGTVLLDKSMLWKGKPEKSLVSYKISCGGRNSRGVITVRHRGRGHKRLYRIIDFKRNKVGVSATVERLEYDPNRTAFIALLSYDDGEKSYIIAPNGLKKGDVVISGEGSDILPGNCLMLKSIPVGTFVHNVELRPGNGGVIARSAGTYAQLMSKDGVYVLLRLSSGEIRKVLSDCRATIGIVSNLDNQNVKLGKAGRNRWLGIRPTVRGVAMNPIDHPHGGGEGKTSGGRNPVTPWGVPTKGKKTRKRNKSSNKYIKRVSDKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: THOC2_MOUSE
Sequence: MAAAAVVVPAEWIKNWEKSGRGEFLHLCRILSENKSHDSSTYRDFQQALYELSYHVIKGNLKHEQASSVLNDISEFREDMPSILADVFCILDIETNCLEEKSKRDYFTQLVLACLYLVSDTVLKERLDPETLESLGLIKQSQQFNQKSVKIKTKLFYKQQKFNLLREENEGYAKLIAELGQDLSGNITSDLILENIKSLIGCFNLDPNRVLDVILEVFECRPEHDDFFISLLESYMSMCEPQTLCHILGFKFKFYQEPSGETPSSLYRVAAVLLQFNLIDLDDLYVHLLPADNCIMDEYKREIVEAKQIVRKLTMVVLSSEKLDERDKEKDKDDEKVEKPPDNQKLGLLEALLKVGDWQHAQNIMDQMPPYYAASHKLIALAICKLIHITVEPLYRRVGVPKGAKGSPVSALQNKRAPKQVESFEDLRRDVFNMFCYLGPHLSHDPILFAKVVRIGKSFMKEFQSDGSKQEDKEKTEVILSCLLSITDQVLLPSLSLMDCNACMSEELWGMFKTFPYQHRYRLYGQWKNETYNGHPLLVKVKAQTIDRAKYIMKRLTKENVKPSGRQIGKLSHSNPTILFDYILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEALANPEKERMKHDDTTISSWLQSLASFCGAVFRKYPIDLAGLLQYVANQLKAGKSFDLLILKEVVQKMAGIEITEEMTMEQLEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKDALLDHDLALPLCLLMAQQRNGVIFQEGGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYIKRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQQHKVHKYITSCEMVMAPVHEAVVSLHVSKVWDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKVQMKAIDDNQEMPPNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKSTKNETITKFLQLCIFPRCIFSAIDAVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIYTVASCTENEASRYGRFLCCMLETVTRWHSDRATYEKECGNYPGFLTILRATGFDGGNKADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQALERRVNKICQEEKEKRPDLYALAMGYSGQLKSRKSHMIPENEFHHKDPPPRNAVASVQNGPGGGTSSSSIGNASKSDESGAEETDKSRERSQCGTKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKVKEKEKEKKEKTPATTPEARALGKDSKEKPKEERPNKEDKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPIVESKSTQEREREKEPSRERDVAKEMKSKENVKGGEKTPVSGSLKSPVPRSDISEPDREQKRRKIDSHPSPSHSSTVKDSLIDLKDSSAKLYINHNPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDITKRRKEENGTMGVSKHKSESPCESQYPNEKDKEKNKSKSSGKEKSSSDSFKSEKMDKISSGGKKESRHDKEKIEKKEKRDSSGGKEEKKHHKSSDKHR
What is the function of this protein?
Required for efficient export of polyadenylated RNA and spliced mRNA.  Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA.  TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.  Plays a role for proper neuronal development.
What are the official names of this protein?
THO complex subunit 2, Tho2.
What is the protein family that this protein belongs to?
Belongs to the THOC2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: NNRE_PEDHC
Sequence: MVRYLSQQEAIDIDQELFNVYKYSVDQLMELAGLSCSIAIYKCYSKLKKILVCCGPGNNGGDGLVAARHLKLFGFEPSVYYPKRTEKPLYQNLTHQCLAMKIDFLNDIPDAKEMSNNYELIVDALFGFSFKPPVRPEFEKVMNVLGKSKVPICSIDIPSGWDVENGCPENGILPDMLISLTAPKKCAKFFNGRFHYLGGRFVPPDLERKYDLKINSEYSGTECCVQLK
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: EFTU_NOSS1
Sequence: MARAKFERTKPHVNIGTIGHVDHGKTTLTAAITMTLAALGQAVAKGYDQIDNAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLAKQVGVPKLVVFLNKEDMMEDAELLELVELELRELLTEYEFDGDDIPIVRGSGLQALEVMTKNPKTQRGENPWVDKIYELMDAVDSYIPDPERDIDKPFLMAVEDVFSITGRGTVATGRIERGKVKVGDVVELVGIRDTRNTTVTGIEMFKKSLDEGMAGDNAGVLLRGIQKADIERGMVLAKPGSITPHTQFEGEVYVLTEKEGGRKTPFFAGYRPQFYVRTTDVTGTIKAFTSDEGETVEMVMPGDRIKVTVELINPIAIEQGMRFAIREGGRTIGAGVVSKIVK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_CHLPB
Sequence: MLTKTRAVVLKEVKFREQSKICSLYTRDFGRISVILKGGRNLKSRLSGLFCTGSLLEVVLYNRSNRDLQLVSEARIIRSPMTAEPSMERFSAIYRLIEILKISTGNEEKNIRLFNALERTLEKLCAPCRNADAAVAWFMLKLISESGFEPSIEQCVTTGKSILPMLQEGSADDLCLTYDPGGVSLPVPAAQKGPPGQRLPVQVYLLMRTLNRLDIRSIDEIDIPADNSRLLCDILQNYCSLHNNYNPSSKNRRIISRILYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RS7_CLOK5
Sequence: MARKGHIGKRDVLPDPVYNSKVVTKLINNIMKDGKKGVAQKICYGAFDIIEQKTSKEPMEVFEEAMNNIMPLLEVKARRIGGATYQVPIEVRPERRQTLGIRWLLVASRKRGEKYMRERLAAELMDAANNTGTAVKKREDTHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: UPPP2_BACLD
Sequence: MNIWDIIVAIILGIVEGLTEYAPVSSTGHMIIVDDVWLKSKELLTPEAANTFKVVIQLGSILAVAFVFKDRILNLLGMKKNITEEQKSGNRLSIAQIAVGLVPAAVLGFLFEDYIDQYLFSVRTVAVGLIAGAVLMLAADWINRRKDTTDSVDRMTYKQALGMGLFQCLALWPGFSRSGSTISGGVILGLSHRAAADFTFIMAIPIMMGASLLSLIKNWAYLSADLLPFFIAGFISAFIVALFVVRFFLRLINKIKLVPFAIYRIVLGLLLFILFL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 2, Bacitracin resistance protein 2, Undecaprenyl pyrophosphate phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL6_CLAM3
Sequence: MSRIGRLPIDVPAGVDVAVDGQHVTVKGPKGELSLTIAQPIRAEVQDGQVLVTRPDDERESRSLHGLTRSLIANNIVGVTTGYTKGLEIVGTGYRVAIKDKGVEFALGFSHPVYVEAPAGISFTVEGVNKMTVVGIDKQLVGETAANIRKIRKPEPYKGKGVRYAGENVRRKAGKSGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: Y1191_ALKOO
Sequence: MVSKEKINRINELARIAKERVLTKLEEEEQQILRKEYIEAFRKSFRKQLDNIELVD
What are the official names of this protein?
UPF0291 protein Clos_1191.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT51A_CONMR
Sequence: MRCVPVFVILLLLIASAPSVDARLKTKDDMPLPSSHANIKRTLQIHRNKRCCPGWELCCEWDEW
What are the official names of this protein?
Conotoxin mr5.1a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSB_NEIM0
Sequence: MKWVTVVLSFALVCCQYSLWFGKGSIGRNSSLREQIAVQEEKNQTLALRNHSLAAEVYDLENGQEAISEIARVELGYIQDGETFYRLIRHNR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: VTC1A_DANRE
Sequence: MTEFWLISAPGEKTCQQTWDKLMTATTRTNNLSTNNKFNIPDLKVGTLDVLVGLSDELAKLDAFVESVVKKVAQYMADVLEDSRDKVQENLLANGVDLVTYVTRFQWDMAKYPIKQSLKNISEIISKQVSQIDNDLKARASAYNNLKGNLQNLERKNAGSLLTRSLADIVKKDDFVLDSEYLITLLVVVPKTNYTDWQRTYETLAEMVVPRSTNLLFEDHDSGLFTVTLFRKAIDDFRHKARENKFTVRDFQYNEEEMKADKEEMTRLSTDKKKQFGPLVRWLKVNFSEAFIAWVHIKALRVFVESVLRYGLPVNFQAMLLQPNKKNMKKLREVLYDLYKHLDSSAAAIIDQSAMDIPGLNLSQQEYYPYVYYKIDCNLLDFK
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit C 1-A, V-ATPase subunit C 1-A, Vacuolar proton pump subunit C 1-A.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase C subunit family.
Protein: FOLD_HAMD5
Sequence: MSAKIMDGKSIAQQIKNEVAHGVQKRLKQGKRAPGLAVILIGENSASQIYVANKRKACEEVGFVSHCYPLPETTSKAELVSLIKQLNQDPEIDGILVQLPLPERFDSANMLEQIRPDKDVDGFHPYNIGSLCQRIPKLRPCTPLGIMTLLARYDLDPCGLNALVVGASNIVGRPMSLELLLAGCTTTVAHRFTQHLQQHVENADLLVVAVGKPSFIPGTWIKPGAIVIDVGINRLQNGRVVGDVEFDMAATRAAWITPVPGGVGPMTVASLLQNTLKACMERT
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HXD11_HUMAN
Sequence: MNDFDECGQSAASMYLPGCAYYVAPSDFASKPSFLSQPSSCQMTFPYSSNLAPHVQPVREVAFRDYGLERAKWPYRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGSPCTKATPGSEPKGAAEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D11, Homeobox protein Hox-4F.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDZD9_MACFA
Sequence: MQKASRKNKKERGVSIKVKTSVHNLSKTQQTKLTVGRLGLGLIIIQHGPYLQITHLIRKGAAANDGKLQPGDVLISVGYANVLGYTLREFLQLLQHITVGTVLQIKVYRDFINIPEEWLEIYDLIPEAKFPVTSTPKKMELAKDESFTSSDDNENVDLDRRLQYYRYPWSTAHHPARRPISISRDWHGYKKKNHTISVGKDIDCDVMIHRDDKKEVKAPSPYWIMVKQDNETSSSSTSSTSDAFWLEDCAQVEEGKAQPVSKFG
What are the official names of this protein?
PDZ domain-containing protein 9.
Protein: RLMN_DESOH
Sequence: MSRNLYYTGPPKFIIKGIMNSTALPQEIQNLTRARFADWLNAHNIAPYRADQVFKWLFVHRAESFDQMTNISKPVRTLLAESFIIGRLKIARTQQSADGTRKYLFELSDGEHIESVLIPEEDHFTLCVSTQVGCAQGCAFCMTAKKGFVRNLTPAEITGQVLGALKTLAPEERLTNIVLMGMGEPLANYDNVITSLDTICDGDCGLQFSTRRVTLSTSGLVPRMAPLGLATTVNLAVSLNATDNKTRDMLMPINKTYPIEVLLEACRTYPLSNRRKITFEYILMAGVNDSEKDALRLVKLLRSIKAKVNLIPFNEHEGAAFKRPDDAAIERFKQILHDRQYTVMTRQSKGADISAACGQLAADIKKYGQNK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LON_WOLPP
Sequence: MSIGRAVNFNSTVLPVLPLRDVVIFPNIMLPLFVGREKSVHALEYAISSSSHQNEIFLIAQKDGSIDNPEPENLYEVGVLANIIQPLIKLPDNAVKVMIHGVRRGRVIEYISSHTLLQARVALDGHYEYGENEDNIDLEALRRSVIDAFDNWCKLSKKSRPEIIIDPIDQVKEVNQIVDMIASHLNIKVSDKQNILEVYNPKERLKKVFALIEREISILSAQNRLYKTIKSQVESTQKVYYLNEQLKAIQKELGEFENGDEGNILNEFEKKINETKLSEEAKEKAITDLKRYKKMNPISPEATVISSYLHWLLDLPWGKYKDAKINLNAAKKILDENHYGIEKVKDRIIEFLAVLKRVKEIKGPILCLVGPPGVGKTSLAKSMAKAVGRDFVRISLGGIRDESEIRGHRKTYIGSMPGKIIQHMKKANSCNPLFLLDEIDKMGSDSRGDPASALLEVLDTEHNKHFTDHYLEVEFDLSSVMFVATANSLNLPHPLRDRMEIIQLSGYTEDEKISIATHHLIPKLKKEHGLHQKEWEITNEALYELIRLYTRESGVRSMERELAKLMRKAVKAILTDKNKKISVETGNLQDYLGVRKYTFGIAENESLVGIVTGLAYTETGGDILMIESVLIPGKGEIKYTGKLGEVMQESIKAAYSYVRSNCLFFGIKPEKFQNNDIHLHVPEGAVPKDGPSAGSAVCTSIVSLMTNIPVNKSVAMTGEVTLRGRVLAIGGLREKLLAALRGSIKTVIIPSENEKDMQEIPANIKEEINVIFAENIDEVIKVALMHPITSIDDNNEISVSTSIENKDNTFPSSETLKH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSC_SALEP
Sequence: MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: G3PT_MOUSE
Sequence: MSRRDVVLTNVTVVQLRRDRCPCPCPCPCPCPCPVIRPPPPKLEDPPPTVEEQPPPPPPPPPPPPPPPPPPPPQIEPDKFEEAPPPPPPPPPPPPPPPPPLQKPARELTVGINGFGRIGRLVLRVCMEKGIRVVAVNDPFIDPEYMVYMFKYDSTHGRYKGNVEHKNGQLVVDNLEINTYQCKDPKEIPWSSIGNPYVVECTGVYLSIEAASAHISSGARRVVVTAPSPDAPMFVMGVNEKDYNPGSMTIVSNASCTTNCLAPLAKVIHENFGIVEGLMTTVHSYTATQKTVDGPSKKDWRGGRGAHQNIIPSSTGAAKAVGKVIPELKGKLTGMAFRVPTPNVSVVDLTCRLAKPASYSAITEAVKAAAKGPLAGILAYTEDQVVSTDFNGNPHSSIFDAKAGIALNDNFVKLVAWYDNEYGYSNRVVDLLRYMFSREK
What is the function of this protein?
May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon.  Required for sperm motility and male fertility.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific, Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2, GAPDH-2, Spermatogenic glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSTCN_HORSE
Sequence: YLDHWLGAPAPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGPV
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.