PharMolix/UniProtQA huggingface dataset:
Protein: METK_AROAE
Sequence: MSKEYLFTSESVSEGHPDKVADQVSDGVLDAILATDPQARVACETLVSTGLVVISGEITTTAHPNYREIAQEVIRRIGYDNSDIGFDYKSCAVLAAINRQSADIAQGVNEGEGLDLDQGAGDQGLMFGYACNETPSLIPLPIYYAHRIMQRQSELRKDGRLNWLRPDAKSQLTVRYVDGKPVAIDTVVVSTQHSPEVSHAQITELVIEEIIKPVLPSALMQGEVRYLINPTGRFVIGGPHGDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSAAYAGRWVAKNIVAAGLADRCEVQVAYAIGVARPVSMMIETFGTGRITDEKIVELVQRHFDLRPKAIIQELNLLRPIYGKTAAYGHFGRDEPEFTWEATDKAAALRADAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_BORPE
Sequence: MSIKSDRWIRRAAEAGMIEPFEPGQVRTAGGNRIVSYGTSSYGYDVRCADEFKIFTNINSTIVDPKQFDEKSFVDFKGDVCIIPPNSFALARTVEYFRIPRSVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKVYAGEGCAQMLFLESDEVCETSYRDRGGKYQGQRGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: YCFP_SALTY
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLVSYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVVFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRHDEALDSQRSAQALHPFYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: GPX1_BOVIN
Sequence: MCAAQRSAAALAAAAPRTVYAFSARPLAGGEPFNLSSLRGKVLLIENVASLUGTTVRDYTQMNDLQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNCLKYVRPGGGFEPNFMLFEKCEVNGEKAHPLFAFLREVLPTPSDDATALMTDPKFITWSPVCRNDVSWNFEKFLVGPDGVPVRRYSRRFLTIDIEPDIETLLSQGASA
What is the function of this protein?
Protects the hemoglobin in erythrocytes from oxidative breakdown.  In platelets, plays a crucial role of glutathione peroxidase in the arachidonic acid metabolism.
What are the official names of this protein?
Glutathione peroxidase 1, GPx-1, GSHPx-1, Cellular glutathione peroxidase.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAW_BACC1
Sequence: MESTIGIDAGGTLTKIAYLNEKMQLAFEKFYSNEQNKIIDWLKQNTGKKQICITGGKAKQLQQLLSNSYKIVELNEFEATLIGVRYILKEEKYDINNFILTNIGTGTSIHYVYNDQYIRAGGTGVGGGTIMGLSKLLTNLEHFEDVIPLTKVGSRKELDITVGDIYGGILSPIDNSLTASNFGKAATIESNYNSSDILATVQGLVGEVVTALSLQFAETKNIDHIIYIGSTLCNNIHLQNIISSYTKYQNKIPIFLQDGGNSGAIGALLHVANKKS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type II pantothenate kinase, PanK-II, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type II pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSM4_MOUSE
Sequence: MRQKEVLAKSFQGPAAVCRTPNSHVYMFNNGSGDSGDSSEEESHQVVLRPRGKEHQKNSSQRPGAGTMVLLQRELAQEDSLNKLALQYGCKVADIKKANNFIREQDLYALKSIKIPVRNHGILTETHQELMPLGASSSETRVTLVDLPEDEDAGGATTQGNQLTDFFKGIDENIERAVHSDVFHGDSCCVEAPDQLLLPITQKPVADGADCGIQWWNAVFLMLLIGIVLPVFYLVYFKIQATGEPSNGLNATVVPNGSMTLSPVPGQAPRLAIPVPTLPASDSQVSPTTQAGA
What are the official names of this protein?
LysM and putative peptidoglycan-binding domain-containing protein 4.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RRF_PROMA
Sequence: MLTQEVELNMQKSVEACQRNFNTIRTGRANTSLLDRLTVEYYGADTPLKSLATISTPDSQTLAIQPFDLGSLGLIEKAISISDLGFTPNNDGKIIRINIPPLTEERRKQFCKLASKYAEEAKISLRNIRRDAIEKIKGSEKDGEFSEDQSRDQQDSIQKITNKYINEIEKNLSGKEEEILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACE_THETS
Sequence: MNLINFSYLNLLFGAGLFSVLESATILNTESDAKKWLTTYNDEAGKYIYDATEAEWNYNTNLTDHNLGISIKKSNDLATFTEQKAIEANKKFVWKNFTDPLLKREFSKITDIGTASLSDEDFQKMSGLNSDLTKIYSTAKVCNKPNDPSGKCYPLDPDLSDIISKSNDLEELTWAWKGWRDASGKHMPDKYDEFVQLLNKAANINGYEDNGDYWRSWYESPTFRKDCEDLWQEIKPFYEQLHAYVRRKLQKKYPQIAFPKEGHIPAHLLGNMWAQSWENIEYLLRPAPDLPSMDITEELVKQNYTALKLFQLSDTFFKSLGLIQMPQPFWEKSMIEKPADRDVVCHASAWDFYNRKDFRIKQCTVVDMHWFMTTHHEMGHIEYYLHYKDQPISFRSGANPGFHEAIADIASLSVATPEYMQSVSLLPNFTDDPNGDLNFLMNQALTKVAFLPFGYLIDQWRWDVFSGDTPRPKYNSKWWHNRCKYQGVYPPVIRSEQDFDAGSKFHVPNNTPYIRYFVAHIIQFQFHEALCKAANNSRPLHRCNIANSKEAGKKLAELMKSGSSIPWPKVLENLTGSEKMSAKSLMAYYKPLIDWPEKRKPRAENWMGGKMSSWIV
What are the official names of this protein?
Angiotensin-converting enzyme, Dipeptidyl carboxypeptidase I, Kininase II, TtACE.
What is the protein family that this protein belongs to?
Belongs to the peptidase M2 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: TX1B3_RAT
Sequence: MSYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQSMLS
What is the function of this protein?
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.  Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway.  Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization.  May play a role in the Rho signaling pathway (By similarity).
What are the official names of this protein?
Tax1-binding protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cell membrane by interaction with membrane proteins.
Protein: CYB_IDIMA
Sequence: MANLRKTHPLAKIFNNSFIDLPTPSNISSWWNFGSLLGLCLIIQIMTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYMLLETWNIGILLLFTTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNIVEWIWGGFSVDKATLNRFFTFHFILPFIITALAMIHLLFLHETGSNNPSGLSSESDKIPFHPYFTIKDILGGMLLIMLLMLLVLFFPDILGDPDNYIPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVIALIMSILILAIIPTIHNSKQRSLTFRPIGQIAFWSLIADLATLTWIGGQPIEHPFMMIGQLASTIYFLILLVLMPATSLLENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RR8_CHAGL
Sequence: MTSDVIANMITSIRNANLRKIKVIELPATKITKSIGKILLQEGFIDNLREREENNKNFLILTLRSQRRKHKASITTIRRISKPGLRIYSNHQEIPKVLGGIGIVILSTSQGIMSDRQARQNRIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS11_ALKOO
Sequence: MAKVAKKRTTRTRRRERKNIERGQAHIQSTFNNSIITLTDMQGNALSQASAGQLGFKGSRKSTPYAAQMAAETAAKAAMEHGLKTVEVYVKGPGAGREAAIRSLQAAGLEVNLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: YC07_KLEPN
Sequence: MNVIHIAETVKGGVATVINNLTENNEIDSHVICPESQSKEIYCAQKTLFSRTGRNISSLSSLFLVIIKTLKYNKFDVIHLHSSFAGFIVRALFAFKLINKKKYKVIYTPHCFSFIMDTKKWKKKVYIYIERILAKQTDCIIANSYYEYKCAVDAGISKNKIKVVYNAVSLDGQEKLERIKKCNENEVQKEKINILFVGRFDKQKGYDYLLNVIKVADVSKYTFNIIGDSVHDVFEKIEKENVVYYGWVDNKELPAYFCENDVLLMPSRWESFGLVAVEAQLYGVPVIANNVASLPEVISDGLTGMLVNFEDANKVVEIMDSHTIHFWNEKKEACREFASNKFRKSDMVNSYVQIYKSY
What are the official names of this protein?
Uncharacterized 41.2 kDa protein in cps region, ORF7.
Protein: CYAY_YERPE
Sequence: MNDSEFHQLADQLMLYIEETLDSFTGDSDIDYETNGGVMTLTFENGSKIVINRQEPLHQVWLATKAGGYHFNYRDGHWYCSRSGEEFLAKLSEAASAQAGENVSFG
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: ACNA_MYCTU
Sequence: MTSKSVNSFGAHDTLKVGEKSYQIYRLDAVPNTAKLPYSLKVLAENLLRNEDGSNITKDHIEAIANWDPKAEPSIEIQYTPARVVMQDFTGVPCIVDLATMREAIADLGGNPDKVNPLAPADLVIDHSVIADLFGRADAFERNVEIEYQRNGERYQFLRWGQGAFDDFKVVPPGTGIVHQVNIEYLASVVMTRDGVAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFRLTGEIQPGVTATDVVLTVTEMLRQHGVVGKFVEFYGEGVAEVPLANRATLGNMSPEFGSTAAIFPIDEETIKYLRFTGRTPEQVALVEAYAKAQGMWHDPKHEPEFSEYLELNLSDVVPSIAGPKRPQDRIALAQAKSTFREQIYHYVGNGSPDSPHDPHSKLDEVVEETFPASDPGQLTFANDDVATDETVHSAAAHADGRVSNPVRVKSDELGEFVLDHGAVVIAAITSCTNTSNPEVMLGAALLARNAVEKGLTSKPWVKTTIAPGSQVVNDYYDRSGLWPYLEKLGFYLVGYGCTTCIGNSGPLPEEISKAVNDNDLSVTAVLSGNRNFEGRINPDVKMNYLASPPLVIAYALAGTMDFDFQTQPLGQDKDGKNVFLRDIWPSQQDVSDTIAAAINQEMFTRNYADVFKGDDRWRNLPTPSGNTFEWDPNSTYVRKPPYFEGMTAKPEPVGNISGARVLALLGDSVTTDHISPAGAIKPGTPAARYLDEHGVDRKDYNSFGSRRGNHEVMIRGTFANIRLRNQLLDDVSGGYTRDFTQPGGPQAFIYDAAQNYAAQHIPLVVFGGKEYGSGSSRDWAAKGTLLLGVRAVIAESFERIHRSNLIGMGVIPLQFPEGKSASSLGLDGTEVFDITGIDVLNDGKTPKTVCVQATKGDGATIEFDAVVRIDTPGEADYYRNGGILQYVLRNILKSG
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  The apo form of AcnA functions as a RNA-binding regulatory protein which binds to selected IRE-like sequences present within the UTRs (untranslated regions) of 3' trxC and 5' IdeR mRNA (PubMed:17384188).  Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate (By similarity).
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, Iron-responsive protein-like, IRP-like, Probable 2-methyl-cis-aconitate hydratase, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: TGL1_YEAST
Sequence: MYFPFLGRLSITDYIIVVLVYIESIISSVLKLIPQPMINLFEWLINFSTSSDDNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNKVVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNKFWDFSIDEFAFFDIPNSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLNRKVSHFIAIAPAMTPKGLHNRIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTLFNLCIDIANKILFNWKSFNILPRQKIASYAKLYSTTSVKSIVHWFQILRSQKFQMFEESDNMLNSLTRPYQIANFPTRTNIKIPILLIYGGIDSLVDIDVMKKNLPFNSVFDVKVDNYEHLDLIWGKDADTLVIAKVLRFIEFFNPGNVSVKTNQLLPSASLVEELPSTTWKTTHPTHGLSYRTHSADRSPLSVQADEADEVHNADNSRFLRRVFSTSAIDEDNENEHQDDTEDQIHKEQQRRLSAYLESSKDLRQLDANSSTTALDALNKE
What is the function of this protein?
Mediates the hydrolysis of steryl esters (SE) (PubMed:10515935, PubMed:14640980, PubMed:15713625).  Preferentially hydrolyzes ergosteryl and zymosteryl esters (PubMed:19111628).  Required for mobilization of SEs from lipid particles/droplets, thereby playing a central role in lipid metabolism and sterol homeostasis.  Sterol intermediates stored in SE and set free by SE hydrolases are recycled to the sterol biosynthetic pathway and converted to the final product, ergosterol, in the endoplasmic reticulum.  Has also weak lipase activity toward triglycerides at neutral pH, however, the physiological relevance of this activity is unclear (PubMed:15922657, PubMed:19111628, PubMed:28866104).
What are the official names of this protein?
Sterol esterase TGL1, Triglyceride lipase-cholesterol esterase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Single-pass membrane protein. Note=Partially retained in the endoplasmic reticulum in cells lacking triacylglycerols and consequently lipid droplets.
Protein: CHEB_SHEFN
Sequence: MAIKVLVVDDSSFFRRRVSEIVNQDPDLEVVAVAVNGKEAVEMAAKLKPQVITMDIEMPVMDGITAVREIMANNPTPILMFSSLTHDGAKATLDALEAGALDFLPKRFEDIATNKDDAILLLQQRIKALGRRRMYRSSSLTPTSTIESRRSTIAAPETNTPRRPLSSRLASTTTPVATRSSLSTTSADRHSANPTTSSISSIRASGKQYKLLLIGTSTGGPVALQKVLTAFPANYPHPIVLIQHMPAAFTPAFAARLNTLCKIEVKEAENGDVMRPGCAYLAPGGMQLMIERSGISGRLKVISGTQEMNYKPCVDITFASASKAFGGDVLAVVLTGMGADGREGARMLKSVGATIWAQDEASCVVYGMPQAVASTGISTHSISLDNMAEAILKESSRG
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTM2_MORBO
Sequence: MLEINKIHQMNCFDFLDQVENKSVQLAVIDPPYNLSKADWDSFDSHNEFLPFTYRWIDKVLDKLDKDGSLYIFNTPFNCAFICQYLVSKGMIFQNWITWDKRDGMGSAKRGFSTGQETILFFSKSKNHTFNYDEVRVPYESTDRIKHASEKGILKNGKRWFPNPNGRLCGEVWHFSSQRHKEKVNGKTVKLTHITPKPRDLIERIIRASSNPNDLVLDCFMGSGTTAIVAKKLGRNFIGCDMNAEYVNQANFVLNQLEIN
What is the function of this protein?
A beta subtype methylase that recognizes the double-stranded sequence 5'-GAAGA-3', methylates A-5 on the top strand, and protects the DNA from cleavage by the MboII endonuclease.  It is not known if the cytosine of the complementary sequence TCTTC is also methylated by this enzyme.
What are the official names of this protein?
Type II methyltransferase M1.MboII, M1.MboII, Adenine-specific methyltransferase MboII, DNA MTase MboIIA, Modification methylase MboII, M.MboII.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: TTCA_PSEF5
Sequence: MGTLTVNQNKLQKRLRRQAGEAVADFNMIEEGDKVMVCLSGGKDSYTMLDVLLHLQKVAPIKFEIVAVNMDQKQPGFPEHVLPAYLKELGIEYHIVEKDTYSVVKELIPEGKTTCSLCSRLRRGTLYTFADEIGATKMALGHHRDDIVETFFLNMFYNGSLKAMPPKLLADDGRNVVIRPLAYCSEKDIQAYSDLKQFPIIPCNLCGSQENLQRQVVKEMLQEWERKTPGRTESIFRGLQNVIPSQLADRNLFDFTSLRIDDSATPRFVNVVNL
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_SULSY
Sequence: MKIKASVKPRCEKCRIIRRNGRVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RL10_SHEAM
Sequence: MALRLEDKKAIVAEVNEAAKGALSAVVADSRGVTVGAMTTLRKTARANGVYVRVVRNTLARRAVEGTAFECLNEVFTGPTLIAFSNEHPGAAARLLKDFAKEQAKFEVKGAAFEGNFIPAADIDRLAKLPTYEEALAQLMMTMKEASAGKFVRTLAALRDQKQEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GCSH_XYLF2
Sequence: MSDIPGDLKFLKSHEWVRIEDNNRAIVGVSDHAQNLLGDLVYVELPNIGDHLDAGATAAVIESVKAASDIYSPVTGKVIEVNTTLSDKPETINEDPYGEGWIMVIEMQAPEEISNLLSPDDYTEVLESDEH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: SCOT1_HUMAN
Sequence: MAALKLLSSGLRLCASARGSGATWYKGCVCSFSTSAHRHTKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIAN
What is the function of this protein?
Key enzyme for ketone body catabolism.  Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate (acetoacetate), and produces acetoacetyl-CoA.  Acetoacetyl-CoA is further metabolized by acetoacetyl-CoA thiolase into two acetyl-CoA molecules which enter the citric acid cycle for energy production (PubMed:10964512).  Forms a dimeric enzyme where both of the subunits are able to form enzyme-CoA thiolester intermediates, but only one subunit is competent to transfer the CoA moiety to the acceptor carboxylate (3-oxo acid) and produce a new acyl-CoA.  Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity).
What are the official names of this protein?
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial, SCOT, 3-oxoacid CoA-transferase 1, Somatic-type succinyl-CoA:3-oxoacid CoA-transferase, SCOT-s, Succinyl-CoA:3-oxoacid CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UGTK5_MANES
Sequence: MGSLASEIPPHAVLVPYPAQGHVNPLMQLGKLLHSRGFYITFVNTEHNHRRLIRSRGQEFIDGLPDFKFEAIPDGLPYTDRDATQHVPSLSDSTRKHCLAPFIDLIAKLKASPDVPPITCIISDGVMAFAIDAARHFGIPEIQFWTTSACGFMAYLHHIELVRRGIVPFKDESFLHDGTLDQPVDFIPGMPNMKLRDMPSFIRVTDVNDIMFDFMGSEAHKSLKADAIILNTYDELEQEVLDAIAARYSKNIYTVGPFILLEKGIPEIKSKAFRSSLWKEDLSCIEWLDKREPDSVVYVNYGCVTTITNEQLNEFAWGLANSKHPFLWIVRPDVVMGESAVLPEEFYEAIKDRGLLVSWVPQDRVLQHPAVGVFLSHCGWNSTIECISGGKPMICWPFFAEQQTNCKYACDVWKTGVELSTNLKREELVSIIKEMMETEIGRERRRRAVEWRKKAEEATSVGGVSYNNFDRFIKEAILQHKTK
What is the function of this protein?
UDP-glucosyltransferase catalyzing in planta synthesis of cyanogenic glucosides.  Able to glucosylate acetone cyanohydrin and 2-hydroxy-2-methylbutyronitrile, forming linamarin and lotaustralin.  Accepts also to some extent, a wide range of potential acceptor substrates, including simple alcohols, flavonoids, isoflavonoids and other hydroxynitriles such as p-hydroxymandelonitrile, mandelonitrile, (E)-4-hydroxy-2-methylbut-2-enenitrile and (E)- 2-(hydroxymethyl)but-2-enenitrile.
What are the official names of this protein?
Linamarin synthase 2, Cyanohydrin UDP-glucosyltransferase UGT85K5.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: ZFAN3_XENLA
Sequence: MGDTGSERSNAPSLPPRCPCGFWGSSKTMNLCSKCFADFQKKQPDEDTAPSTSSSQSDLFPSETDSDNGNTSIPTPTVNPTQQLPTELNVDSPSKEDCGPCTDSAHVSLTTPSKRSCDSDSQSEDDTSPMKRPRLLDSGDRPDNSSRSKQKSRRRCFRCQIKLELVQQELGSCRCGYVFCMLHRLPEQHDCTFDHMGRGREEAIMKMVKLDRKVGRSCQRIGEGCS
What are the official names of this protein?
AN1-type zinc finger protein 3 homolog.
Protein: PHOSP_HIRRV
Sequence: MSDNEGEQFFDIPKNALDRVEARTMCPREDGKVVRKQAPLKEEPRLEAEQKRSPKKQEKPRGMLPLEQLVLKYVVVVCSLDALREFGGLIAQIRQSHQADMTRHLEAVATEHRANLQALTKSQQEHEKVSKEILSAVISIRSNLNENSSPRHKPLDLDQVNAERALGFGVGYRTALNVFGKLRGITPEEAGSQEVKNMAIREAEEDEYEGSRSFFKKVLDMVKKTMR
What is the function of this protein?
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication.  Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the novirhabdovirus protein P family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: AROE_HAHCH
Sequence: MDMYAVVGNPVSHSKSPKIHGMFAQQTGESLEYTAIQAPLDGFRETVESFFIGGGKGLNVTVPFKEQAWNIVSERSHRAELAGAVNTLLQRDGRLFGDNTDGEGLVRDICVNQGVALSGKKILLVGAGGAVKGVMAPLLDEGPASIVVANRTVSKAEDLARIFGRNGVVCARAFADLEGPFDVIINGTSASLAGDIPPLPDAVIASHTFTYDMMYSLRDTAFVAWAKARGAAHCCDGLGMLVEQAAAAFYLWRGVRPDTAPVLAGLRQGD
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: SYME_ECO57
Sequence: MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESELMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
What is the function of this protein?
Involved in the degradation and recycling of damaged RNA.  It is itself a target for degradation by the ATP-dependent protease Lon.
What are the official names of this protein?
Endoribonuclease SymE.
What is the protein family that this protein belongs to?
Belongs to the SymE family.
What are the subcellular locations of this protein?
Cytoplasm.