PharMolix/UniProtQA huggingface dataset:
Protein: ZKSC1_PONAB
Sequence: MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSSLQDTPPPDPEIFRQRFRRFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHFKHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEEWGCQNLARRNLSRDNKQENYGSAFPQGGENRNENEESTSKAETAEDSASHGETAGRFQKEFGEKRDQEGKTGERQQKNPEEKTGKEKRDSGPATGKDKKTITGERGPREKGKGLGRSFSLSSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASEYSPASLDAFGAFLKSCV
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein with KRAB and SCAN domains 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MES17_ARATH
Sequence: MAEENQEETLELKPSRKPPHFVLIHGMSLGSWCWYKIKCLMEVSGFTVTCIDLKSSGIDSSSVDSLTTFDQYNQPLIDFLSSFPEQEQVILVGHSAGGLSLTSAIQRFPKKICLAVFIGASMLKNGLQTDEDMKDGVPDLSEHGDVYELGFGLGPENPPTSAIIKPEYRRKLLYHMSPQQECSLAALMMRPAPILALTTAKLEEEEKEKGQEEQVPRVYIKTLLDRVMKPEQQDAMIRRWPPSQVYELESDHSPFFSNPFVLFGLLIKAAVSVGSI
What is the function of this protein?
Methylesterase that efficiently and specifically hydrolyzes methyl indole-3-acetic acid (MeIAA) to IAA (auxin).  MeIAA is believed to be an inactive form of auxin that needs to be demethylated to exert a biological effect.
What are the official names of this protein?
Methylesterase 17, AtMES17, Methyl indole-3-acetic acid esterase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Methylesterase family.
Protein: AAS_ECOSE
Sequence: MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGILLGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQITLHILPPTQVEMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGK_BACAH
Sequence: MNKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLVEQGAKVILASHLGRPKGQAVEELRLTPVAARLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFYAGEEKNDAELAKEFAALADIFVNDAFGAAHRAHASTAGIADYLPAVSGLLMEKELEVLGKALSNPERPFTAIIGGAKVKDKIGVIRHLLDKVDNLIIGGGLAYTFVKALGHEIGLSLCEDDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATTKIVGIDSIPSNWEGVDIGPKTREIYADVIKNSKLVVWNGPMGVFEMTPFAEGTKAVGQALADAEGTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLEFMEGKELPGVVCLNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKP1B_DICDI
Sequence: MSLVKLESSDEKVFEIEKEIACMSVTIKNMIEDIGESDAPIPLPNVTSTILEKVLDYCRHHHQHPSPQGDDKKDEKRLDDIPPYDRDFCKVDQPTLFELILAANYLDIKPLLDVTCKTVANMIRGKTPEEIRKIFNIKNDFTPEEEEQIRKENEWCEDKGGN
What are the official names of this protein?
SCF ubiquitin ligase complex protein SKP1b, Glycoprotein FP21 isoform B.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: METK1_CATRO
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRSIGFVSDDVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKRPEEIGAGDQGHMFGYATDETPEFMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNENGAMVPVRVHTVVISTQHDETVTNDQIAADLKEHVIKPVIPEKYLDERTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVANGLARRCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKENFDFRPGMIAINLDLKRGGSGRFLKTAAYGHFGRDDPDFTWEVVKPLKWEKAAN
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_ALKMQ
Sequence: MALVPVVVEQTSRGERSYDIFSRLLKERIIFLGDEINDVTASLLVAQLLFLEAEDPDKDIQIYINSPGGSITAGMAIYDTMNYIKPDVSTICVGMAASMGAFLLAAGAKGKRFALPNAEVMIHQPLGGTRGQAEDIRIHAERIVKLRDTLNKILVERTGQPLERVQKDTDRDFFMEAKEAKEYGIIDEVISSRK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO3_METAC
Sequence: MTMEVDILELSDRSAKFVLSNVSTAFANGIRRAMVADVPTLAIEYVNLYDNTSVLYDEQLALRLSLIPLATDIETYLPQAECDVCGGEGCPACEVSLTLSAEGPGTVYSRDLISSDPKIQPADPNVPIVELKKGQKLVLEAIAHMGYGRDSVKWQAGVACGYKNMPVITIENCDACGHCAAECPKGIISVEEAGAKIAEEDIMKCSICRLCEQVCDINAIKVDFYENSFVFTMESDGSYTAKDLVLNAANVIKGKAEEMLAILDQL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo3, DNA-directed RNA polymerase subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUP3_MOUSE
Sequence: MKLLLPLLLLLCLELTLVCIHAEESSSMERNFNVEQISGYWFSIAEASYEREKIEEHGSMRAFVENITVLENSLVFKFHLIVNEECTEMTAIGEQTEKAGIYYMNYDGFNTFSILKTDYDNYIMIHLINKKDGKTFQLMELYGREPDLSLDIKEKFAKLCEEHGIIRENIIDLTNVNRCLEARE
What is the function of this protein?
Binds pheromones that are released from drying urine of males.  These pheromones affect the sexual behavior of females.
What are the official names of this protein?
Major urinary protein 3, MUP 3, Non-group 1/group 2 MUP15.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SECY2_STRPA
Sequence: MLRKLQKYWKKSIIFQRFTWMIGIVFIYMLGRQIPIPTVGVDKVVVGNASDSQLLENFGAITGIQFSNMTLFSLGIGPTMTMMILWRFLITFKLIGSWTSNKVNRLQFLLTLAIALLQSFGITNDSKFLLIFGYSHSTLRIITIILLTTGTFILNWLCKINSERGIGGMTVVILVNMILTFQSNIIRYFSVQQFKFSSLIQYGLVFFVALSILIWFNILLYKGEYRIPIQRVGLNTPYHASSYLPIRVTPAGAMPFMYGMTLMMLPPYIFVVLLHIFPGNQILEYLSVHIGLSQLPGVICYIFLLYFLSIGFAYYNYDPYEISKNMRNNGDYISGKKPGEETIKYIQYVVNSFAQFGAFTVIIFGGLPMLAVLLQGQGKNSVSIALLISNAYIIVSLLLGVIEQVDTMNSWKKYKNLI
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required for correct glycosylation and export of Fap1, a serine-rich fimbrial adhesin.  Potentially the central subunit of a protein translocation channel.
What are the official names of this protein?
Accessory Sec system protein translocase subunit SecY2.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TM241_MOUSE
Sequence: MNVRRSLLGLTFCTCYLASHLTNKYVLSVLKFTYPTLFQGWQTFIGGLLLHMSWKLGWVELHSSPRSDVLIWLPASALFVGIIYAGSKALSRLAVPVFFILHNVAEVLTCGYQKCVWKEKTSLSKICSALFLLAAAGCLPFQDSQFDPDGYFWALIHIFCVGSYKILRKSRKPTVLSDIDQQYLNYIFSMVLLAFASHPTGDLFGALDFPFLYFYRFHGSCCASGVLGFFLMLSTVRLRSILAPGQCAAWILCAKVVTAGLSMLLFDMALTKATVGCFLLGGLGEALLVFSERRSSS
What are the official names of this protein?
Transmembrane protein 241.
What is the protein family that this protein belongs to?
Belongs to the TMEM241 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GCH1_RICTY
Sequence: MNKPTREEAKEAVRTLLRFIGEDPTREGLLKTPDRVINSYMEIFSGYGKDVQEILNTKFYDTYNFQDLISLEGIKFTSFCEHHILPFNGTVHIAYIPDNCIIGVSKLARIVNIFSRRLQIQEKMTVQIAESIQESLKPLGVAIKISAFHSCMSMRGVMHDNSVMNTMYYTGIFAEQQKYRHEFLNFIAKR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CBRB_DICD3
Sequence: MSHAVIPTGRRIAPGQVLAGGGVCLLALAVLSLMVGPVWIAPSQVLGALWHPDPLNVSHILVTSTRLSRTLIAIVVGAGLAVAGALMQVLTRNPLASPGLFGINAGAMFFLIVCVSLFPKVAMSVWLWSAFAGAAVAGCLVWLIGTMGKGSLNPLRMVLAGAAITAMFAAFSQAMLVVNQEGLDTVLFWLAGSVADRELATVLPLMGYCLAALVGALLLSGQVNVLNAGEAIARGLGQRTGRIRLLMSLLVVALAGGAVAMAGSIGFVGLIVPHMARKLLPADHRWLLPGCALLGACLLLLADILARVVIVPQEVPVGVMTALFGAPFFIFLLRRGGRYG
What is the function of this protein?
Part of the binding-protein-dependent transport system CbrABCD for uptake of the siderophore achromobactin.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Achromobactin transport system permease protein CbrB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_MYCS2
Sequence: MANIKSQIKRIRTNERRRLRNQSVKSSLRTAIRGFREAVDAGDKDKASELLHATSRKLDKAASKGVIHPNQAANKKSALALALNKL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: YDAF_ECOLI
Sequence: MQKIDLGNNESLVCGVFPNQDGTFTAMTYTKSKTFKTETGARRWLEKHTVS
What are the official names of this protein?
Uncharacterized protein YdaF.
What is the protein family that this protein belongs to?
To E.coli YdfA.
Protein: FUS6_GIBF5
Sequence: MASAKDAQPAPEKSLSSDPQPEPSKKGARFWLIFVAISLTTFLAALDTSIISTALPTITADLGSESLYVWIIDAYLLASTATIPIFAQAANIYGRRSLTLIAVCIFTLGSGLCGGAHNTAMMVGGRAVQGIGGGGILTMSEIVVCDMVSIRERGMYAGIIGGVWAIAAVVAPVMGGAFAQNISWRWIFYINLPIAGVSLVALGLFLKLSRPPSGTFKEQMSRIDWGGSVLLIGSVTSIVLALSWGGSEHPWSGWQTIVPLVIGLLALVAFFAYQGAPWLREPTMPLRLFSNRTSSTLLVISFIHSLLLYWICYFLPVYFQAVKEASPTRSAVMLFPIACTSAPAGVAAGITITKTGKYRVWHFTGFVLMSIACGLFTLLDAQSSTGRWVGFQILFGVGTGTVFTSTLPPILASLPDSDVATATGAWTFIRNFGSIWGVAIPAAVFNNHVNHAAPKISDSSVKSLLVDGGAYEHATQHFIKSLSPNPDLKTQVIQVYLEGLKVVWQVSLAFCLLGFILCFFVRSLTLRDELNTEFGLKEEKPNSNNMSSEEGVVRD
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C (PubMed:23932525).  Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (PubMed:23932525).  The other FUS cluster members are not essential for fusarin C biosynthesis (PubMed:23932525).
What are the official names of this protein?
Efflux pump FUS6, Fusarin biosynthesis protein 6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PTEN_XENLA
Sequence: MTAIIKEFVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTNKFSCRVAQYPFEDHNPPQLELIKPFCEDLDQLLSENENVAAIHCKAGKGRTGVMICAYLLHRGKFPRAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNSLEYRPVPLLFHKIEFETIPMFSGSTCNPQFVVYQLKVKIFTSTAGPKRAEKLMYFDFPQPLPVCGDIKVEFFHKQNKVMKKEKMFHFWVNTFFIPGPEEYSEKVENGTLVGEQELDGIYSTERSDNDKEYLTLALTKNDLDKANKDKANRLFSPNFKVKLFFTKTVEESSNSEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQITQITKV
What is the function of this protein?
Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins.  Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
What are the official names of this protein?
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog.
What is the protein family that this protein belongs to?
Belongs to the PTEN phosphatase protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body.
Protein: BEPG_BRUSU
Sequence: MLSSVFINRPRLAIVIAIVITLAGLIAVTRIPVAQFPDIVPPQVSVTATYPGASAETVEAAIAQPIEAQVNGVDDMIYMSSTSGNNGTYTLTVTFKVGSDPNLNTVNVQNRVRLAEANLPQEVTRLGVTVKKQSSSFLQIITLLSPDSRYDELFLNNYGVINVVDRLARVPGVGQAQSFGTFNYSMRIWFNTDALTSLNLTPNDIVNAISSQNVQAAVGRLGAPPMTDQQQIQLTLTTQGRLTDAKQFENIIIRANPDGSSVRLKDVARVELAAQSYDTIGRLNGKPASVIAVYQAPGSNAVAAAEGVRNVMEQLKQSFPAGLDYKITYDTTVFVSSTIHEVIKTLLEAFVLVVVVVFIFLGNFRATLIPTLAVPVSLIGTFAVLLVLGFSANTISLFAMILAIGIVVDDAIVVVENVERVMAETGLPPKEAAKQAMQEITAPIIAITLVLLSVFVPVAFIPGITGALYAQFALTVSVAMLISAINALTLSPALCGVFLKPHQGRKKSLYGRTMDKLSSGIEKISDGYAHIVRRLVRMAFLSIVLVAGLGAGAYFLNTIVPTGFLPEEDQGLFFVQVNLPPAASQSRTAAVVSEIEADITKMAGVADVTSVTGFSFIDGLAVSNAGLMIVTLKPLEERLKDNITVFDVIAEVNRRTAAIPSAVAITMNLPPILGLGSSGGFQYQLEDQEGQSPQQLASVAQGLVMAANQNPKLSRVFTTFATDTPQLNLNIDRQKALSLGVSPNNIIQALQSTLGGYFVNNFNTLGRTWQVIIQGEQQDRKTVEDIYRINVRSSHGDMVPLRSLVSVEERLGPLYITRYNNYRSASIQGNAAPGVSSGEALAAMAQVSKTTLPSGYGYEWTGTALQELQAAGQTSMILALAVLFAYLFLVALYESWTIPVGVLLSVTAGLAGAMLALWITGLSNDIYAQIGIVVLIALASKNGILIVEFAKERREEGVPLEQAAIIGARQRFRPVMMTSFAFILGLVPLVIAVGAAAASRRAVGTSVFGGMIAASAVGIFLIPMLYVVLERVREWGHARILRKPLYEEEKQEKADGDASGPTVPPTQPEDRGLS
What is the function of this protein?
May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE.
What are the official names of this protein?
Efflux pump membrane transporter BepG.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEU1_LYSSC
Sequence: MRKIDIFDTTLRDGEQSAGINLNTAEKIEIAKQLERLGVTIIEAGFPASSPGDFDAVHRIAETVKNSVVTGLARCIQKDIDTTWEAIKGAQQPHIHIFLATSPIHMEYKLKKSPEQVIEQAVEAVKYAKKYFPLVQWSAEDAFRSDREFLVRIMNEVVTAGATTINVPDTVGYASPYEYGALFKYLLENVKGADKVKFSAHCHDDLGMATANTLAAIENGAAQVEGTINGIGERAGNVALEEIAVALHIRKDYYQVETGIQLQEIKRTSQLVSKLTNVVIQPNKAIVGRNAFAHESGIHQDGVLKNPETYEIISPALIGEGEIPLVLGKHSGRAAFRDRAETLGFDLSDEKLNKAFVEFKKLADRKKEITEEDLLTLLTEQQIQLEDVPLFELKMVQVQYGTENIPTATAIVLTPEGLEKTVVATGAGSVEAIFNTLEQLVPNAVHVIDYRVTSVGKGRDALGEAVVNIRYDHVSTTGRNSSQDVLEASAKAYLNAINRHLIKESLRAHPV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RL33_TRIEI
Sequence: MAKGVRIIITLECTECRTNPNKRSQGVSRYTSTKNRRNTTSRLELKKFCTHCNRHTVHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PURA_ECOHS
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UN13C_HUMAN
Sequence: MVANFFKSLILPYIHKLCKGMFTKKLGNTNKNKEYRQQKKDQDFPTAGQTKSPKFSYTFKSTVKKIAKCSSTHNLSTEEDEASKEFSLSPTFSYRVAIANGLQKNAKVTNSDNEDLLQELSSIESSYSESLNELRSSTENQAQSTHTMPVRRNRKSSSSLAPSEGSSDGERTLHGLKLGALRKLRKWKKSQECVSSDSELSTMKKSWGIRSKSLDRTVRNPKTNALEPGFSSSGCISQTHDVMEMIFKELQGISQIETELSELRGHVNALKHSIDEISSSVEVVQSEIEQLRTGFVQSRRETRDIHDYIKHLGHMGSKASLRFLNVTEERFEYVESVVYQILIDKMGFSDAPNAIKIEFAQRIGHQRDCPNAKPRPILVYFETPQQRDSVLKKSYKLKGTGIGISTDILTHDIRERKEKGIPSSQTYESMAIKLSTPEPKIKKNNWQSPDDSDEDLESDLNRNSYAVLSKSELLTKGSTSKPSSKSHSARSKNKTANSSRISNKSDYDKISSQLPESDILEKQTTTHYADATPLWHSQSDFFTAKLSRSESDFSKLCQSYSEDFSENQFFTRTNGSSLLSSSDRELWQRKQEGTATLYDSPKDQHLNGGVQGIQGQTETENTETVDSGMSNGMVCASGDRSHYSDSQLSLHEDLSPWKEWNQGADLGLDSSTQEGFDYETNSLFDQQLDVYNKDLEYLGKCHSDLQDDSESYDLTQDDNSSPCPGLDNEPQGQWVGQYDSYQGANSNELYQNQNQLSMMYRSQSELQSDDSEDAPPKSWHSRLSIDLSDKTFSFPKFGSTLQRAKSALEVVWNKSTQSLSGYEDSGSSLMGRFRTLSQSTANESSTTLDSDVYTEPYYYKAEDEEDYTEPVADNETDYVEVMEQVLAKLENRTSITETDEQMQAYDHLSYETPYETPQDEGYDGPADDMVSEEGLEPLNETSAEMEIREDENQNIPEQPVEITKPKRIRPSFKEAALRAYKKQMAELEEKILAGDSSSVDEKARIVSGNDLDASKFSALQVCGGAGGGLYGIDSMPDLRRKKTLPIVRDVAMTLAARKSGLSLAMVIRTSLNNEELKMHVFKKTLQALIYPMSSTIPHNFEVWTATTPTYCYECEGLLWGIARQGMKCLECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDKTQTIITAMKERMKIREKNRPEVFEVIQEMFQISKEDFVQFTKAAKQSVLDGTSKWSAKITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFYFECHNSTDRIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLKINVEIKGEEKVAPYHIQYTCLHENLFHYLTEVKSNGGVKIPEVKGDEAWKVFFDDASQEIVDEFAMRYGIESIYQAMTHFSCLSSKYMCPGVPAVMSTLLANINAFYAHTTVSTNIQVSASDRFAATNFGREKFIKLLDQLHNSLRIDLSKYRENFPASNTERLQDLKSTVDLLTSITFFRMKVLELQSPPKASMVVKDCVRACLDSTYKYIFDNCHELYSQLTDPSKKQDIPREDQGPTTKNLDFWPQLITLMVTIIDEDKTAYTPVLNQFPQELNMGKISAEIMWTLFALDMKYALEEHENQRLCKSTDYMNLHFKVKWFYNEYVRELPAFKDAVPEYSLWFEPFVMQWLDENEDVSMEFLHGALGRDKKDGFQQTSEHALFSCSVVDVFAQLNQSFEIIKKLECPNPEALSHLMRRFAKTINKVLLQYAAIVSSDFSSHCDKENVPCILMNNIQQLRVQLEKMFESMGGKELDSEASTILKELQVKLSGVLDELSVTYGESFQVIIEECIKQMSFELNQMRANGNTTSNKNSAAMDAEIVLRSLMDFLDKTLSLSAKICEKTVLKRVLKELWKLVLNKIEKQIVLPPLTDQTGPQMIFIAAKDLGQLSKLKEHMIREDARGLTPRQCAIMEVVLATIKQYFHAGGNGLKKNFLEKSPDLQSLRYALSLYTQTTDALIKKFIDTQTSQSRSSKDAVGQISVHVDITATPGTGDHKVTVKVIAINDLNWQTTAMFRPFVEVCILGPNLGDKKRKQGTKTKSNTWSPKYNETFQFILGKENRPGAYELHLSVKDYCFAREDRIIGMTVIQLQNIAEKGSYGAWYPLLKNISMDETGLTILRILSQRTSDDVAKEFVRLKSETRSTEESA
What is the function of this protein?
May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway.  May be involved in the regulation of synaptic transmission at parallel fiber - Purkinje cell synapses (By similarity).
What are the official names of this protein?
Protein unc-13 homolog C, Munc13-3.
What is the protein family that this protein belongs to?
Belongs to the unc-13 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Presynaptic cell membrane; Peripheral membrane protein. Note=Localized to presynaptic structures.
Protein: KPRS2_LISMO
Sequence: MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSNIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Putative ribose-phosphate pyrophosphokinase 2, RPPK 2, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 2, Phosphoribosyl diphosphate synthase 2, Phosphoribosyl pyrophosphate synthase 2, P-Rib-PP synthase 2, PRPP synthase 2, PRPPase 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDX49_DROME
Sequence: MQRKEANPFQILGLRPWLVKQLTKLGLKGATPIQQKCIPAILAGQDCIGAAKTGSGKTFAFALPILERLSEEPVSHFALVLTPTHELAYQISEQFLVAGQAMGVRVCVVSGGTDQMVESQKLMQRPHIVVAMPGRLADHLTGCDTFSFDNLKYLVVDEADRMLNGDFDESLSIIERCLPKTRQNLFFSATMKDFIKESSIFPIASDCFEWSQDSDVATVETLDQRYLLCADYDRDMVLIEALRKYREENENANVMIFTNTKKYCQLLSMTLKNMEIDNVCLHGFMRQKERVAALSRFKSNQIRTLIATDVAARGLDIPSVELVMNHMLPRTPKEYIHRVGRTARAGRKGMSISIFRFPRDLELLAAIEEEINTKLTEHPIDQRMVERIFMQVNVTRRESEMQLDNNDFDERAQNYRRKTWIMEGKDPDQMEALYRKKQKDKLREIRRKRKLQHAEPAASEEGKALLQDERFKSVDSARFEKKGKGRSRATQEDTPTKPLKRLNKEKPVAQKGRADVKKDKA
What is the function of this protein?
Probable ATP-binding RNA helicase.
What are the official names of this protein?
Probable ATP-dependent RNA helicase Dbp45A, DEAD box protein 45A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
Protein: YZ10_CAEEL
Sequence: MPVEQDGLTGGRGVPHPNSAAGQALSGKTGGSSVPHPNSAAGQALSGGMTGGSAVPHPNSAAGQELTNKNLEEKSVLEGGTQVKPWLKNQPDLANIREQNHQ
What are the official names of this protein?
Uncharacterized protein F08B12.4.
Protein: ACADS_HUMAN
Sequence: MAAALLARASGPARRALCPRAWRQLHTIYQSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLLRSYRS
What is the function of this protein?
Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats (By similarity).  The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (By similarity).  Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains (PubMed:21237683, PubMed:11134486).
What are the official names of this protein?
Short-chain specific acyl-CoA dehydrogenase, mitochondrial, SCAD, Butyryl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.