PharMolix/UniProtQA huggingface dataset:
Protein: IMA3_MOUSE
Sequence: MADNEKLDNQRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDQAETIANLIEECGGLEKIEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDPSLVPESVQGGTFGFNSSTNVPTEGFQF
What is the function of this protein?
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1.  Binds specifically and directly to substrates containing either a simple or bipartite NLS motif.  Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
What are the official names of this protein?
Importin subunit alpha-3, Importin alpha Q1, Qip1, Karyopherin subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRE_ACIAD
Sequence: MTTPSSFNPQAFIELALSRGVLKFGEFTLKSGRVSPYFFNAGLLNDGEALSLLAQGYADQLMQCQHVDVIFGPAYKGIPFVAATAVALSQLHAKSVPWGFNRKEAKDHGEGGVLVGASVEGKKVWIIDDVITAGTAIREVVTILKNAGATIAGVLVALDRQERGQGQLSAIQEVQQELEIPVHALITMKDLMNYLDAKGETQALAKMEDYRLKYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CD11A_HUMAN
Sequence: MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPGEARPAPAQKPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
What is the function of this protein?
Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis.  The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7.  The p58 isoform may act as a negative regulator of normal cell cycle progression.
What are the official names of this protein?
Cyclin-dependent kinase 11A, Cell division cycle 2-like protein kinase 2, Cell division protein kinase 11A, Galactosyltransferase-associated protein kinase p58/GTA, PITSLRE serine/threonine-protein kinase CDC2L2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GPDA_STRTD
Sequence: MKKQKIAVLGPGSWGTALAQVLNDNGHEVRIWGNIPEQIDEINEKHTNTRYFKDVILDENIKAYKELSEALDSVNAILFVVPTKVTRLVAKQVAELLDHKVVVMHASKGLEPGTHERLSTILEEEIPSEMRSEIVVVSGPSHAEETIVRDITLITAASKDLETARYVQGIFSNSYFRLYTNSDVIGVETAGALKNIIAVGAGALHGMGYGDNAKAAIITRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSIHSRNWRAGYALGRGEKLEDIERNMGMVIEGISTTKVAYEIAQELGVYMPITTAIYKSIYEGADIKESILDMMSNELRSENEWDKK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSPF_SHIBS
Sequence: MPIKKPCLKLNLDSLNVVRSEIPQMLSANERLKNNFNILYNQIRQYPAYYFKVASNVPTYSDICQFFSVMYQGFQIVNHSGDVFIHACRENPQSKGDFVGDKFHISIAREQVPLAFQILSGLLFSEDSPIDKWKITDMNRVSQQSRVGIGAQFTLYVKSDQECSQYSALLLHKIRQFIMCLESNLLRSKIAPGEYPASDVRPEDWKYVSYRNELRSDRDGSERQEQMLREEPFYRLMIE
What is the function of this protein?
Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases p38, phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3.  This epigenetic modification results in inhibition of the transcription of a specific subset of pro-inflammatory genes, and ultimately to a reduced immune response against the invading pathogen.  The diminished immune response enhances the bacterium's ability to disseminate and multiply within the host (By similarity).
What are the official names of this protein?
Phosphothreonine lyase OspF, Effector protein OspF.
What is the protein family that this protein belongs to?
Belongs to the phosphothreonine lyase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system (TTSS). Localizes in the nucleus of the infected cell (By similarity).
Protein: RL31_CAMJR
Sequence: MKKEIHPEYVECKVSCACGNTFTTKSNKAELRVDICSNCHPFFTGSEKIVDAAGRVEKFKKKYAMQ
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RS10_STAAC
Sequence: MAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPTEKSVYTIIRAVHMYKDSREQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GSPG_KLEOK
Sequence: MRRQSQRGFTLLEIMVVIVIMGILASLVVPNLMGNKDKADRQKVVSDIVALESALDMYKLDNSRYPTTEQGLQALITKPSVPPEARYYPQDGYIRRLPQDPWGGDYQLVSPGQHGQIDIFSSGQDGVPGTDDDIGNWTLSKK
What is the function of this protein?
Core component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm (PubMed:8809775).  Pseudopilin (pilin-like) protein that polymerizes to form the pseudopilus.  Further polymerization triggers pseudopilus growth (PubMed:15491357).
What are the official names of this protein?
Type II secretion system core protein G, T2SS core protein G, General secretion pathway protein G.
What is the protein family that this protein belongs to?
Belongs to the GSP G family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CYSA1_RHIME
Sequence: MEVRVESLRKEFGRFPALVDVTLDILSGELIALLGPSGSGKTTLLRLIAGLESPTEGMIFFGDEDASKRTVQERNIGFVFQHYALFRHMTVLDNVTFGLKVRPANRRPPAAEIRRRALDLIDLVQLSGLEKRYPAQLSGGQRQRVALARAMAVEPSVLLLDEPFGALDAQVRKELRRWLREIHDRTGYTTLFVTHDQEEALELADRVVVMSKGAIEQVGTPDEIYDHPVSPFVYGFIGQSNCLNVTLANGEIWFEGRPIGLRAANEPDGQATLFFRPHDVELIEGGSGCLAGRVTASRRVAGTRHLELDLGKTQSSIEVELPPELASSADRTRIALRPTKWKLFCGE
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA 1, Sulfate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS7_ANADF
Sequence: MKQASPRAGGAKARRGQVARKTKETDVSVELRLEPGESSIATGLPFFDHMLDQIARHGGLTLSVQAKGDLQVDAHHTVEDVGIGLGEALRQATADKAGLARYGVAVVPLDEALVEAVVDLSGRPHLTFNAKLPSGKRFIGAYDVDLTQDFLQAFVNHARICLHVNVRYGRNLHHVVEAIFKATARALRAATAREGTALPSTKGLL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_LEUCK
Sequence: MVVSVQEIGQRAKTAATDVAGLTITTRNDLLRQMSQALLDNQSAIMAANKEDIAAYANTLSQPMIKRLTLDQPTIKAIATSLLAVVALPDPLAGPFDTWQTHVDLKIVKRVVPLGVVAMIYEARPNVTIDAAALTLKSGNAVILRGGKEAIHSNTVLANILRDVLRDNALNPDIIQLITDTSHESVNVLLNMRDYVDVLIPRGSAKFIDFVVANATVPVIETGAGNTHIFVDQSADQKQAIAIIHNAKTQKPAVCNAAEKLLVHVAIAAEFIPKITEKLVRAHVELRGDQASHQLDPRISLASEQDWDTEYNDLIMGIKIVSGTNDAIDWINNHTTHHSETIISKSSENVAQFMNQVDAAVVYQNASSRFTDGFEFGFGAEIGISTQKLHARGPMGLPALTTIKYEVFGQGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_BRUME
Sequence: MNIFADFDARIKKTLQDIDLKPKDGGELDLSRIGVEPPRDASHGDIATNAAMVLSKAVGQNPRELAARIAEALKADEDVESVDVAGPGFINLRLKASYWQRELLVMLNEGTDFGRSRLGAGKKVNVEYVSANPTGPMHVGHCRGAVVGDVLANLLKFAGYDVVKEYYINDAGAQIDVLARSVMLRYREALGESIGEIPAGLYPGDYLVRVGQELAGEFGTKLLEMPEAEALAIVKDRTIDAMMAMIRADLDALNVHHDVFYSERKLHVDHARAIRNAINDLTLKGHVYKGKLPPPKGQLPEDWEDREQTLFRSTEVGDDIDRPLMKSDGSFTYFAGDVAYFKDKYDHGFNEMIYVLGADHGGYVKRLEAVARAVSDGKAKLTVLLCQLVKLFRNGEPVRMSKRAGEFITLRDVVDEVGRDPVRFMMLYRKNDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQAADQLGLVDLDRVAMGSHFEKLTDESEIALVRKLAEYPRLIESAAIHQEPHRLAFYLYDLASSFHSQWNRGAENPDLRFIKVNDPDLSLARLGLVQVVSDVLTSGLTIIGADAPTEMR
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_ERYLH
Sequence: MRILLTNDDGIHAPGFEVLEDIARELSDEIWVCAPAEEQSGAGHSLTLHHPVRLRQLGERRYSVTGTPTDSVMLALRTVLEDKQPDLILSGVNRGANLGDDITYSGTASAAMEGALGGIKSIALSQVYKRDAEHELFDAARTYGADVIRKLIDAPFGDRTLININFPPLPADKVRGIRAVRQGFHDYSRGSVVKGRDPRGLEYYWFGLYAIEHTLDHGTDLEAIDEGFVSVTPLQLDLTQHSLLSVIGERFE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INHBE_RAT
Sequence: MGLSNVQLWTILLWALAWVQSTRSACPSCGAPTLTPQGERALVLELAKQQILEGLHLTSRPRITRPLPQAALTRALRRLQPRSMVPGNREKVISFATSIDKSTSTYRSVLTFQLSPLWSHHLYHARLWLHVPPSFPATLYLRIFGCGTTRCRGSRTFLAEHQTTSSGWHALTLPSSGLRSEESGVTKLQLEFRPLDLNSTTARLPRLLLDTAGQQRPFLELKIRANEPGAGRARRRTPTCESETPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAGSSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS
What is the function of this protein?
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.  Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.  Inhibins appear to oppose the functions of activins.
What are the official names of this protein?
Inhibin beta E chain, Activin beta-E chain.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEXA_YERPA
Sequence: MKALTTRQQEVYDLVRDHLAQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLMEEEEGLPLIGRVAAGEPLLAQQHIEGHYKVDPSLFKPGADFLLRVNGMSMRDIGILDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNIVHLLPENSEFQPIVVDLREQSFTIEGLAVGVIRNGDWI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CRP4_LIMPO
Sequence: MKTFHGPTFGTAVFLYLLLFLTSALEEGEITSKVKFPPSSSPSFPRLVMVGTLPDLQEITLCYWFKVNHLKSTLTIFSYNTAKNDNELLTSLEKQGAFHMNVHGAPQLKVQCPNKIHIGKWHHVCHTWSSWEGEATIGVDGFHCKGNATGIAMGVTLSQGGLVVLGQEQDSVGGEYDAEQSLEGELSELNLWNTVLNHEQIKHLSKCAHPSERHIHGNIIQWDKTQFQAYDGVVLSPNEICA
What is the function of this protein?
Might serve the role of immunoglobulins.
What are the official names of this protein?
C-reactive protein 1.4.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NEU1B_MOUSE
Sequence: MGNTVHRTLPDSSPPARLLATRPCYGPGPERRAVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESTFADTLTPLRLGQARLSACPPPGSHDAANFDNNELENNQVVAKLGHLALGRPDAAVPCVARERPRPASSPALLDAELRFHATRGPDVSLSADRRLACAPRPDGGRTLVFSERPLRPGESLCVEVGRPGLAAPAAVAFGITSCDPGALRPSELPADPAALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLAVNGRPRGRLLCVDTSQALWAFFAVRGGVAGQLRLLGTLQSSSETMTPSGSFSGSQDDSDSDMTFGVNQSSSASESSLVTAPSSPLSPPVSPAFSAPEPTGSRNGECTVCFDSEVDTVIYTCGHMCLCHGCGLRLRRQARACCPICRRPIKDVIKIYRP
What is the function of this protein?
E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands.
What are the official names of this protein?
E3 ubiquitin-protein ligase NEURL1B, Neuralized-2, NEUR2, Neuralized-like protein 1B, Neuralized-like protein 2, Neuralized-like protein 3, RING-type E3 ubiquitin transferase NEURL1B.
Protein: TRMD_BACAA
Sequence: MKIDILTLFPDMFTGVFGSSILKKAQEKEAVELRVVNFRDYTTSKHNSVDDYPYGGGAGMVLTPQPIFDAVEDLTKETERKPRVVLMCPQGERFTQKKAEELAEEEHLIFVCGHYEGYDERIREHLVTDEISIGDYVLTGGELASMVITDSVVRLLPGVLGNHASQVEDSFSTGLLEHPHYTRPADFRGMKVPDVLMSGNHKNIDEWRHKESLRRTYTRRPDLLEERELSKQEKKWLEQIKEGK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM79_RAT
Sequence: MTEPETLALLDMKDTEISEKSPPQASVLQPEEEGGTESPGAESLRVGSSVGSPTVREGPEDGPDSTISEAATLPWGTDPHPSAPLPDPPGWRDIGPELLESEAPIKSEEPLKEDANLLPEKTVRAFVPIDLQCIERKPQEERIKHREAGPGELRNFLPARLSHPEPPERKWAEAVVRPPGRSCGGCGSCGGREALRAVASVVAALIFFPCLLYGAYAFLPFDAPRLPTMSSRLVYTLRCGVFATFPIVLGLLVYGLSLLCFSALRPFGEPRREVEIHRQYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAISRLIYWLTFAVGRSFRGFGYGLTFLPLLAMLVWNLYYMFVVEPERMLSASESRLDYPDHVRSVSDYRPRSWG
What is the function of this protein?
Contributes to the epidermal integrity and skin barrier function.  Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial cell formation (By similarity).
What are the official names of this protein?
Transmembrane protein 79, Mattrin.
What are the subcellular locations of this protein?
Lysosome. Golgi apparatus, trans- Golgi network. Membrane; Multi-pass membrane protein. Note=Colocalized with TGOLN2 in the trans-Golgi network. Colocalized with LAMP1 in the lysosome (By similarity).
Protein: RECA_SINMW
Sequence: MAQNSLRLVEDKSVDKSKALEAALSQIERAFGKGSIMKLGAKDSVVEIETVSTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLALQTIAEAQKKGGICGFVDAEHALDPIYARKLGVDLENLLISQPDTGEQALEITDTLVRSGAIDVLVVDSVAALVPRAEIEGEMGDSLPGMQARLMSQALRKLTASISKSNCMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGSVKEREEVVGNQTRVKVVKNKMAPPFKQVEFDIMYGEGVSKTGELIDLGVKAGIVEKSGAWFSYNSQRLGQGRENAKLFLRDNPELLREIETALRQNAGLIADRFLENGGPESEGDEAADM
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INV2_ARATH
Sequence: MSAPKFGYVLLLIVLINISNNGVDAFHKVFKKLQSKSTSLESVSPLHRTAYHFQPPRHWINDPNAPMLYKGVYHLFYQYNPKGAVWGNIVWAHSVSKDLINWEALEPAIYPSKWFDINGTWSGSATHVPGKGPVILYTGITENQTQIQNYAIPQDLSDPYLKTWIKPDDNPIVKPDNGENGSAFRDPTTAWFNKKDGYWRMLVGSKRKNRGIAYMYKSRDFKKWVKSKRPIHSRKKTGMWECPDFFPVSVTDKKNGLDFSYDGPNAKHVLKVSLDLTRYEYYTLGTYDTKKDRYRPDGYTPDGWDGLRFDYGNYYASKTFFDDKTNRRILWGWANESDTVQDDTVKGWAGIQLIPRTILLDSSGKQLVFWPIEEIESLRGKNVQMTNQKMEMGQRFEVQGITPAQVDVDVTFNVGNLEKAEKFDESFATKPLELCNLKGSNVNGGVGPFGLITLATSDLEEYTPVFFRVFKDAASNKPKVLMCSDAKPSSLKKDTGTDAKERMYKPSFAGFVDVGLLDGKISLRSLIDHSVVESFGAKGKTVITSRVYPTKAVGEKAHLFVFNNGSQPVTVESLNAWNMQKPLKMNQGAK
What are the official names of this protein?
Beta-fructofuranosidase, insoluble isoenzyme CWINV2, Cell wall beta-fructosidase 2, AtbetaFRUCT2, Cell wall invertase 2, AtcwINV2, Sucrose hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Secreted, cell wall. Note=Associated to the cell wall.
Protein: DNAJ_XANOR
Sequence: MSKRDYYEVLGVARGASDEELKKAYRRCAMKHHPDRNPGDAAAEAAFKECKEAYEVLSDGNKRRAYDAHGHAAFEHGMGGGGGGPGSPDMGDIFGDIFGNIFGGGAAGPRAARRGADVGYVLELDLEEAVAGIERRIEIPTLIECVSCHGSGSEDGKVQTCGTCHGRGQVRIQRGIFAMQQSCPHCDGRGTLIQNPCKTCHGAGRVEENKVLSIKVPAGVDTGDRIRLAGEGEAGPAGTPPGDLYVEVRVREHAIFQRDGDDLHCEVPIRISQAALGDTVRVATLGGEAEIRIPAETQTGKLFRLRGKGVRSVRSRSEGDLYCRVVVETPVNLTADQRELLQQFEATFTGEDARKHSPKSATFIDGVKGFWDRMTS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_KINRD
Sequence: MPTPTKGPRLGGGPAHEKLILANLATALFEHRSITTTEAKAKRLRPHAEKLISFAKKGDLASRRQVMKTIRDKSVVHFLFTEIGPAMAERNGGYTRIVKIGPRKGDNAPMAVIQLVMEPVSAKQGVVREAERAAAVSAPAADEVVVGDEAPAAESTDAAQVEAGGVEQPDTLPDADAPATADEGVEVDAAEVDPSDEKKDQA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: APGM_THEKO
Sequence: MKKRKGLLIILDGLGDRPIKEFGGKTPLEYANTPNMDRLAKMGILGQQDPIKPGQPAGSDTAHLSIFGYDPYKVYRGRGFLEALGVGLDLNEDDLAFRVNFATIENGIITDRRAGRISTEEAHELAKAVQENVKLPVDFIFVGATGHRAVLVLRGMAKGYRVGENDPHEAGKPPQEFTWEDEESKKVAEILEEFVQKAHEVLDKHPINEKRRKEGKPPANYLLIRGAGTYPDIPMKFTEQWKVKAGAVIAVSLVKGVARAIGFDVYTPEGATGEYNTDVMAKAKKTVELLKDYDFVFLHFKPTDAAGHDNNPKLKAEMIEKADRMIGYILEHIDLEDVVIAITGDHSTPCEVMNHSGDPVPLLIAGGGVRPDHTESFGERECMRGGIGRIKGHDIVPIMMDLMNRSEKFGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: RN114_RAT
Sequence: MAAAQPESRDGAAQSAKPASETDPLSRFTCPVCLEVFEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAAELERQIESIETSCHGCRKDFVLSKIRAHVASCSKYQSYIMEGVKATTKDASLQQRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLTHSTDTKSVVCPICASMPWGDPSYRSANFMEHIQRRHRFSYDTFVDYDVDEDDMINQVLQRSIIDQ
What is the function of this protein?
E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates.  In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity.  Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3.  May promote the ubiquitination of TRAF6 as well.  Acts also as a negative regulator of T-cell activation.  Inhibits cellular dsRNA responses and interferon production by targeting MAVS component for proteasomal degradation.  Ubiquitinates the CDK inhibitor CDKN1A leading to its degradationand probably also CDKN1B and CDKN1C.  This activity stimulates cell cycle G1-to-S phase transition and suppresses cellular senescence.  May play a role in spermatogenesis.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF114, RING finger protein 114, RING-type E3 ubiquitin transferase RNF114, Zinc finger protein 313.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TUAB_BACSU
Sequence: MPSITKQIMSGAKWTSISTMCITIIQIVQFALLGNMMTLTEFGLVGMITTVTVFAQIVLDMGFGAALIQRDDATERQLSTLYWLNIMTGVLLFVLLYVSSPVIAGFYQREELVFLVRILAIMFLIAPIGQQYQYMLQKQLHFNTLSKIEIFSNVLSFGYLAIAVFMMDAILAYVISQVLLQSSKGILYWAVYRKKWHPAFVFDLRGMKDFFSFGAFQLSSRLVNRLGANIDMILIGRFIGAEALGIYNLAYQIVTIPVLKINPIVTRVAFPIFAKNKYENSVIREGFLNMTKMLALVSFPLLIGLVSVSDAFITAVFGEKWLAAVPILNVLAIVGILRVLMNPNGSVLLAKGRADLAFYWDSGVLLLYGLSLFAAVQTGSLLTVAWVYAIISVVNFLIGRWLLAYVIKLNLSAYFQSIMKPFLITAAMGIIAFGVSLSTEHFSMQAEMRLAISVAAGALCYLFLLVKAYPQTKSKLLRKGRLS
What is the function of this protein?
Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane.
What are the official names of this protein?
Teichuronic acid biosynthesis protein TuaB.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.