PharMolix/UniProtQA huggingface dataset:
Protein: CAPSD_TMGMV
Sequence: MPYTINSPSQFVYLSSAYADPVQLINLCTNALGNQFQTQQARTTVQQQFADAWKPVPSMTVRFPASDFYVYRYNSTLDPLITALLNSFDTRNRIIEVDNQPAPNTTEIVNATQRVDDATVAIRASINNLANELVRGTGMFNQAGFETASGLVWTTTPAT
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: DPO3X_BUCAI
Sequence: MNYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGIGKTTIARLLAKSLNCQNGITSDPCRQCIICKEIEKGLCLDVIEIDGASRTKVEEMREILDSIYYSPIKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFVLATTDVDRIPKTIISRCLYFKLQIISEEKIFKFLKYILIKESIDTDEYSLKKIAYHAHGSIRDALNLLEHAINLGNGHVNIKNVTDMLGLLPEKYSFLLTDAVLKKDSKKTMLLLNKISSIGVEWEEILIEMLRFLYHISTSQSFPLVWEKIFTEKYKNQIQKIAQNNKKTNIQLCYQILLNGRKELKFAPSQKIGVEMSLLRVISAI
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the DnaX/STICHEL family.
Protein: SOSSC_DROER
Sequence: MAFPTTSAQQAETNRKILEEIQTKKQLLAGGIINLGLSPANQMPAPQLLGQPTTVNPDFQAGVGIATNATSTARSAFNPTSSTTLGFFIPQDSYFGNSFIPVLPRLEPLPSPATTPTTPNAPPSHNISK
What are the official names of this protein?
SOSS complex subunit C homolog.
What is the protein family that this protein belongs to?
Belongs to the SOSS-C family.
Protein: AZOR3_BURL3
Sequence: MFKLLQIDSSPMGDASISRRLTQEYARNWLRAHPDGRVVERDLCRIAMPPIDAAWIAANFTPPDRRTAQQNEMLALSTTFTTELRDADEYVIGVPMHNWGPSAHFKLWLDHIVRQGETVETTPSGPRGLLGGRRATFVIAAGWRYGPDAERAQRNFLEPWLRTLFGFLGVEDMRFVMADGAADVFTGKADSAVFLAPHVDAVRALFA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 3, Azo-dye reductase 3, FMN-dependent NADH-azo compound oxidoreductase 3, FMN-dependent NADH-azoreductase 3.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: LDH_SELRU
Sequence: MNNRRKIVVIGASNVGSAVANKIADFQLATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIKFHLGDYEDCKDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLDVATYVVSTQFDYPRNLILGTGTMLETYRFRRILADKYQVDPKNINGYVLGEHGNAAFVAWSTTGCAGFPIDDLDEYFHRTEKLSHEAVEQELVQVAYDVINKKGFTNTGIAMAACRFIKSVLYDEHTILPCSAVLEGEYGIKDVALSIPRMVCADGIMRSFEVHLTDDELEKMHKAAQSVRSALDGAGIK
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4103_ARATH
Sequence: MACFLNCVRFDVSKTITDKPTSQGSGVTCYNSWDDVETLTSNFSRLIGSGGYSSIYMARFSGSDKAALKVHVSSHRLYQVFRLELDILLRLQHPNIVKLLGYFDDSEENGALLLEYLPQGNLQEKLQSNSKQVLQWRNRVAIALQLVQAIEHIHEKCSPQIVHGDIKSSNVLLDKNFDCKLCDFGSAKVGFSSMVQPPTMSPRSRQVKMVGSPGYTDPHYLRTGIASKKMDMYGFGVVVLELVSGKEAFSAERGEMLVHIAAPLMNEILDSSVDISEDKVRQFLDPRLLRDSLDIDEVKTMLSVAAVCISSKLSLRPSAAQVADTLIKEIPSLSFLGCGKGV
What are the official names of this protein?
Probable receptor-like protein kinase At4g10390.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: MRAY_LACP3
Sequence: MQLAQMLIPMVSAFAITIMFMPLFIGYMRYKKEGQVIREEGPSWHEKKSGTPTMGGLIFIAAIIVSAIWVGIWQHQLTLSVWVSLFILVLYGLLGFYDDFEKLVHHRNEGLKAWQKLAGQILGAIIFLIAYFHEGFDHTLWVPIIGNVSAAWFYVLFVIVWLVGFSNAVNLTDGLDGLVAGQTTISFGTYAIIAAHDGRTDVLIVCLVTIGAMLGFLMFNHKPAQIFMGDLGSLALGGMLAVVAILLHREWSLLLIGIIYVTETASVILQVGSFKLTGKRIFLMSPIHHHFEMKGWSEWQIDLTFWLVGLIGSGIYLAFFL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPE18_MYCTU
Sequence: MVDFGALPPEINSARMYAGPGSASLVAAAQMWDSVASDLFSAASAFQSVVWGLTVGSWIGSSAGLMVAAASPYVAWMSVTAGQAELTAAQVRVAAAAYETAYGLTVPPPVIAENRAELMILIATNLLGQNTPAIAVNEAEYGEMWAQDAAAMFGYAAATATATATLLPFEEAPEMTSAGGLLEQAAAVEEASDTAAANQLMNNVPQALQQLAQPTQGTTPSSKLGGLWKTVSPHRSPISNMVSMANNHMSMTNSGVSMTNTLSSMLKGFAPAAAAQAVQTAAQNGVRAMSSLGSSLGSSGLGGGVAANLGRAASVGSLSVPQAWAAANQAVTPAARALPLTSLTSAAERGPGQMLGGLPVGQMGARAGGGLSGVLRVPPRPYVMPHSPAAG
What is the function of this protein?
Could be a crucial virulence factor for intracellular survival of M. tuberculosis (PubMed:23300718).  Favors development of Th2-type response, and down-regulates the pro-inflammatory and Th1-type response (PubMed:19880448, PubMed:21451109).  Specifically interacts with the human Toll-like receptor 2 (TLR2), leading to an early and sustained activation of p38 MAPK, which induces IL-10 production and activates Th2-type immune response (PubMed:19880448).  Also inhibits pro-inflammatory cytokines IL-12p40 and TNF-alpha production.  Acts by up-regulating the expression as well as tyrosine phosphorylation of suppressor of cytokine signaling 3 (SOCS-3), leading to the inhibition of phosphorylation of I-kappa-B-alpha, thereby preventing nuclear translocation of the NF-kappa-B/REL subunits and expression of NF-kappa-B regulated genes like IL-12 and TNF-alpha.  Induction of SOCS-3 probably depends on the activation of p38 MAPK (PubMed:21451109).
What are the official names of this protein?
PPE family protein PPE18.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell surface.
Protein: K1A_STIME
Sequence: MKSQVIAAVLLIAFCLCVVVTARMELQDVEDMENGFQKRRSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC
What is the function of this protein?
Inhibits voltage-gated potassium channels (Kv) with higher potency for Kv1. 1/KCNA1 and Kv1. 3/KCNA3.
What are the official names of this protein?
Kappa-stichotoxin-Smt1a, Kappa-SHTX-Smt1a, Kappa-stichotoxin-Sm1a, Kappa-SHTX-Sm1a, Potassium channel peptide toxin sm-k, SmK.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1a subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CFI2_ARATH
Sequence: MPLPSVTPLHVDAFTFPPAVESPASHKRLFLGGAGKFVIVTVIGVYLEAMALPSISAKWKGKNAKELTESVPFFRQLVTGEFEKLARVTMKKRLTGIQYSEKVVENCEEIMKASGKYTRSEAKAIDQFLMVFKNQDFPPGSSIIFAICPKGSLTIAFSKEERVPKTGKAVIKNKLLGEAVLESMIGKNGVSPATRKSLAERLSKLMNKKDPYNEANVNVATKN
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase 2, Chalcone isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: GCH1_SHELP
Sequence: MALSEAAKQVQTALLERGLETPMVPCGLSSEARKEKIEHHMREILTLMSLDLRDDSLVETPKRIAKMYVDEIFSGLDYENFPKITVIENKMGFDEMVKVNDISLTSTCEHHLVTIDGVATVAYLPRKNIIGLSKINRIVRFFAQRPQVQERLTQQVLVALQTLLETKDVAVKMDAVHYCVKSRGVMDSTSTTTTTALGGIFKSNPATRAEFLSN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CPSF2_HUMAN
Sequence: MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSMDIIDSLRKHVHQIDAVLLSHPDPLHLGALPYAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTPGTLARFLIDNPSEKITEIELRKRVKLEGKELEEYLEKEKLKKEAAKKLEQSKEADIDSSDESDIEEDIDQPSAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGDEPMDQDLSDVPTKCISTTESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDSEMQVEAPSDSSVIAQQKAMKSLFGDDEKETGEESEIIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV
What is the function of this protein?
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.  Involved in the histone 3' end pre-mRNA processing.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor 100 kDa subunit, CPSF 100 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRB_STRPF
Sequence: MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDHQKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALGTDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGLKIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELDVLMLLRVQHERHDGHQSFSKESYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADSLVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y1431_ACTP7
Sequence: MEAVERIENPYGIRLRIFLQPKASRDQIVGLHDSELKIAITAPPVDGAANAHLLKYLSKLFKVPKSSIVLEKGELQRHKQLFVPEPKLIPKEIEALL
What are the official names of this protein?
UPF0235 protein APP7_1431.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: APT_MASNA
Sequence: MSEPELQLVARRIRSFPDFPIPGVLFRDISPLLKDPDSFRASIRLLASHLKSLHGGKIDYIAGLDSRGFLFGPSLAQELGVGCVLIRKRGKLPGPTLSASYALEYGKAELEIQKDALEPGQRVVIVDDLLATGGTMCAACELLNQLRAEVVECVSLVELTSLKGRERLGPIPFFSLLQYD
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_DEHM1
Sequence: MPGYYLWTIGCQMNQAESERLGRLFELWGYSLADKAEDAELVLVNSCVVREHAENKVINRLHILRKLKDKNPRLKIALTGCLVGQDIASVRKKFPFVDYIFQPGALPDWGEIPEGFILPLKPPVSASITIMQGCDNFCTYCIVPYRRGREKSRSISELCCEAAELVRRGSREVVLLGQNVDSYGHDLPEKPCLADLLYALSDIPGLLRIRFLTSHPKDISQKLIDAMASLHKVCHSLSLPVQAGADTILAAMRRGYTSEQYRELVGRLKTAMPDISLQTDLIVGFPSETAEQFDQSYKLMSDIGYDAIHVAAYSPRPQTAAARDMADDVPVAEKKRRLKLIEDLQKETVSKANSALVDTFAEVLVEGRQKNKWQGRTLGGKLVFLESDLPLEGCLINVKIFKASPWSLQAKLVKILES
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2EB_YEAST
Sequence: MSKNRDPLLANLNAFKSKVKSAPVIAPAKVGQKKTNDTVITIDGNTRKRTASERAQENTLNSAKNPVLVDIKKEAGSNSSNAISLDDDDDDEDFGSSPSKKVRPGSIAAAALQANQTDISKSHDSSKLLWATEYIQKKGKPVLVNELLDYLSMKKDDKVIELLKKLDRIEFDPKKGTFKYLSTYDVHSPSELLKLLRSQVTFKGISCKDLKDGWPQCDETINQLEEDSKILVLRTKKDKTPRYVWYNSGGNLKCIDEEFVKMWENVQLPQFAELPRKLQDLGLKPASVDPATIKRQTKRVEVKKKRQRKGKITNTHMTGILKDYSHRV
What is the function of this protein?
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH.  Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity).
What are the official names of this protein?
Transcription initiation factor IIE subunit beta, TFIIE-beta, Factor A 43 kDa subunit, Transcription factor A small subunit.
What is the protein family that this protein belongs to?
Belongs to the TFIIE beta subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LV1B_MESMA
Sequence: MVKMQVIFIAFIAVIACSMVYGDSLSPWNEGDTYYGCQRQTDEFCNKICKLHLASGGSCQQPAPFVKLCTCQGIDYDNSFFFGALEKQCPKLRG
What is the function of this protein?
The monomer edited version, named BmKITx, similar to alpha-toxins, may modulate voltage-gated sodium channels (Nav) and may block voltage-gated potassium channels (Kv).
What are the official names of this protein?
HMG-CoA reductase inhibitor bumarsin, JCH2, Lipolysis-activating peptide 1-beta chain, BmLVP1-beta, LVP1-beta, Neurotoxin KITx, BmKITx, Putative toxin BmKTXLP2.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ENPP1_CAEEL
Sequence: MRRSFYASSTENTPMMMTQARVLSTGTTDNGTIRYDEVDETKRWFNRRFCFLTVIGIAVLLLAMVVIVVIVLLLTQLKAANSNAQNAMSSSKVQLEELTRKLSQPLEQLGPTLERLSNMPGFPMGPSPTTQTPPGVPPISPIVTGPNTTPESPRRSPKARYEWKGCQNLGKCELSGYTKPPLVILSLDGFAREYVDRNIVQTLNHIADCGVKADKVYPSYPSKTFPNHYSIVTGLWPESHGITDNSVFDPTISPVLESMKSTKYEKFFEGEPIWSVYKRKTGKKANCLFWVGCAYNNSGYAPDVAPAYNQELPFRNRIDTVVEWLKLPVDERPGLITAYLHEPDNAGHYQVDEEDVDEKLAEIDENLDYLMSRLSEEKLLECINFAILSDHGMQLIDKTYYFQDYLDLKGLITAKGVVGRVYINDTTISVNDVVDKFRCKIDTVKTNTRSDVPTRKHYSRDPRVGEVLLEGRAGVTFYKSKADDYELSGDHGYDYFNPKMHTIFYARGPSFKQNTTISPYQNIQYMNLWMNLLGIEGAVETNGTIGFFDNILTNPPRRDNPTNVIGECPMIAFPSVLKCSGNVSAETLNQLSVKLTNCAFSPTNIPLYSDNHCFQNYCDNSVIVSRKGNDARRAIIEVLSRDEASNPSNFTFLNAKYQSNCPSHIPTGSLTIRQNSQLSSMVDERIDVPNNFLLKVLDPLQAKSMEYLNKFGKMYVISGTATDINHDGIADSNGSVITHIYRIMLICNSTWLLMNPPLCTDSDSMDTLSFIFPITEQSTIDCMSSDDILLDYTATIFDVERISGFQFGIGALSQNQNTIIRRKISTKLW
What is the function of this protein?
Probable phosphodiesterase.
What are the official names of this protein?
Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: ANMK_BACAC
Sequence: MYIAGVMSGTSLDGIDVALVRIEGSGVESKVELIHFTTVPFCNDIKSEIQQALSIENSNVQLICSLNFKLGLCFANAVKEVCKEANFSLEQLDLIGSHGQTIYHQPKQDGNRIPSTLQIGEPAVIAYETNTTVISNFRTMDMAAGGQGAPLVPYSEVILYRDPSKNRLLQNIGGISNVTVIPNQQSDQNVIAFDTGPGNMIIDEVCQRLFQLSYDQNGEIAKQGRVVDEILTYCMSHPFLKMNPPKSTGREQFGEKFASELLKRFEKHSKENILTTVTMFTANSIVHHYKKFILPYYEIDEVILGGGGSYNSTLVEMLRNGLKDENCAIFIQEDIGYSSEAKEAIAFAILANETHHCNPSNVPSATGAKQSVVFGNITFPPV
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ITR4_LUFAE
Sequence: ICPRILMPCSSDSDCLAECICLENGFCG
What is the function of this protein?
Inhibits trypsin.
What are the official names of this protein?
Trypsin inhibitor 4, TGTI-I, Trypsin inhibitor I.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: IHFA_LEGPL
Sequence: MNALSKAIMAETLCDELKLNKPVAKEMVENFFEELRHALENGQHVKLSGFGNFTLRDKPQRPGRNPKTGEEIPVEARRVVTFKPGLKLKTKIEKIGK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: Y222_TREPA
Sequence: MWKRGVGALLWGMVLLRSFVAYADSQAATGGLLKEIMGEVASIRLESNMLKQQLRERHAESAALKKALQTLDVKLEKAAKALEESEHALSESKELIETLRSELEILRQRVNALNMRLRRLEITNNVLIGVAVVCGVAAIGAGIYAAVK
What are the official names of this protein?
Uncharacterized protein TP_0222.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACYP_BORBU
Sequence: MYKQQYFISGKVQGVGFRFFTEQIANNMKLKGFVKNLNDGRVEIVAFFNTKEQMKKFEKLLNGNKYSNIKNIEKIVLDENYPFQFNDFKIYY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RL27_AQUAE
Sequence: MASKASGGSTRNGRDSISKRLGVKRYDGQFVKAGNIIVRQRGTRIYPGKNVGMGSDYTLFALKDGYVYFETRRKKKFVSVLSPEEWEKVMAQKNGKVH
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: HP27_TAMSI
Sequence: MYEAGKRASFMGGAGIWILALSVLMHVVCSETQGNPESCNVPGPQGPPGMRGPPGTPGKPGPPGWNGFPGLPGPPGPPGMTVNCHSKGTSAFAVKANELPPAPSQPVIFKEALHDAQGHFDLATGVFTCPVPGLYQFGFHIEAVQRAVKVSLMRNGTQVMEREAEAQDGYEHISGTAILQLGMEDRVWLENKLSQTDLERGTVQAVFSGFLIHEN
What is the function of this protein?
Plasma proteins HP-20, HP-25, HP-27 and HP-55 form a 140 kDa complex via disulfide bonds in the plasma and are hibernation specific.
What are the official names of this protein?
Hibernation-associated plasma protein HP-27, Hibernator-specific blood complex 27 kDa subunit.
What are the subcellular locations of this protein?
Secreted.
Protein: HPRK_GEOSW
Sequence: MPKVRTKDIIEKFQLELVSGAEGIHRPITTSDLSRPGIEMAGYFTYYPAERIQLLGKTELSFYETLSLEEKKMRMERLCTDITPGIIISRGLEVPPELIEASERQSVPVMRSTMKTTRLSSRLTNYLESKLAPTTAVHGVLVDVYGVGVLITGKSGVGKSETALELVKRGHRLVADDCVEIRQEDEGVLVGSAPELIEHLLEIRGLGIINMMTLFGAGAVRTHKRISLVIDLELWDPNKQYDRLGLEEEKVKILDTELTKLTIPVRPGRNLAVIVEVAAMNFRLKRMGVNAAEEFSARLTDAIEDGEHDYE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue.  Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: AMPN_HAEIN
Sequence: MLAKAKYRKDYKQPDFTVTDIYLDFQLDPKHTVVTAITKFQRLNNEATSLCLDGHSFQFSSIKFNGEPFSDYQQDGESLTLDLKDKSADEFEIEIVTFLVPAENTSLQGLYQSGEGICTQCEAEGFRQITYMLDRPDVLARYITKITADKTKYPFLLSNGNRIASGELEDGRHWVEWNDPFPKPSYLFALVAGDFDLLQDKFITKSGREVALELYVDRGNLNRATWAMESLKKAMKWDEDRFNLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKFVLANPQTATDDDYLAIESVIAHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDTGSRAVNRINNVKFLRTVQFAEDASPMSHPIRPEKVIEMNNFYTVTVYEKGAEVIRMLHTLLGEQGFQKGMQLYIAENDGKAATCEDFVSAMERANNLDLNQFRRWYSQSGTPELLISDAYDEKTHTYRLTVSQSTPPTADQMEKVNLHIPLKVALYDANGTKQMLQHNGELLSDVLNVTEKDQVFEFHGIYGRPIPALLCDFSAPVKLDYDYKTEQLLGLLKFADNQFIRWDAAQMLFAQELRRNVVRFQQGEALEISPEILTALSYVLNHYEKDIELATLILTLPKEMEFAESFKTIDPDGISAARAFMQAQIAESLKDDFLRVYTHIRLNDYQVTQQDIALRVMRNLCLTYLAYTNLGNNLVQKHYNNANNMTDTLAALSVATKAALLCRDVLLADFEQKWQHDGLVMDKWFALQATRPDDNVLEIIQLLMDHPSFNFNNPNRLRSLVGSFANHNLKAFHNVSGSGYRFLTDVLIRLNESNPQVAARLIEPLIRFSRFDAQRQTLMKRALERLSVVENLSKDLFEKIEKALQ
What is the function of this protein?
Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.
What are the official names of this protein?
Aminopeptidase N, Alpha-aminoacylpeptide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NUCB2_RAT
Sequence: MRWRTIQARYCFLLVPCVLTALEAVPIDVDKTKVHNVEPVESARIEPPDTGLYYDEYLKQVIEVLETDPHFREKLQKADIEEIRSGRLSQELDLVSHKVRTRLDELKRQEVGRLRMLIKAKLDALQDTGMNHHLLLKQFEHLNHQNPDTFESKDLDMLIKAATADLEQYDRTRHEEFKKYEMMKEHERREYLKTLSEEKRKEEEAKFAEMKRKHEDHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNNDGFLDEQELEALFTKELDKVYNPQNAEDDMIEMEEERLRMREHVMNEIDNNKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEEELKEYESIIAIQESELKKKADELQKQKEELQRQHDHLEAQKQEYQQAVQQLEQKKFQQGIAPSGPAGELKFEPHT
What is the function of this protein?
Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner.  May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
What are the official names of this protein?
Nucleobindin-2, DNA-binding protein NEFA, Prepronesfatin.
What is the protein family that this protein belongs to?
Belongs to the nucleobindin family.
What are the subcellular locations of this protein?
Golgi apparatus. Endoplasmic reticulum. Nucleus envelope. Membrane; Peripheral membrane protein. Cytoplasm. Secreted. SUBCELLULAR LOCATION: [Nesfatin-1]: Secreted.
Protein: RL10_GLUOX
Sequence: MKAGLTRRQVLDRTEKRAFVEFLADVFGSTSMVVVTQNKGLTVADVTELRRRIRAAGATYKVAKNRLASRALDGTQFDGIAPLLKGPTALAWSEDPASVAKVIVEFAKTNDKLVVLGGALGSQALGVDGIKALAELPSLDELRAKLVGMINTPATRIAGVVQAPAGQLARVFGAYAKAGEAEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CIS1_ASHGO
Sequence: MEPFVITASECDCNSAHSSRVSKDGYALSDELSNETMFLTQVKYIFEGEEDHIDDNTMQEINTDIVNVVIVELDETLEIKNVELISDEYQLLGFSNDADNDLNLTILSEFPADVSPGTRDLGKLVTRYQHQNKHLKHMLQEL
What is the function of this protein?
Plays a role in starvation-induced autophagy.  Involved in mitophagy.  Functions with ATG17 and ATG29 at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions.  May be involved in microtubule function, such as chromosome segregation and karyogamy (By similarity).
What are the official names of this protein?
Autophagy-related protein 31, Protein CIS1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Preautophagosomal structure.