PharMolix/UniProtQA huggingface dataset:
Protein: CG121_NEUCR
Sequence: MALETLQIEHVPSDHHVYAALFRDVQNVDFLQAQLIGKNPEFEYAFIDASVIISRTHLFAAIFRALNTLTEGTLQTPNVHSDIVIGLSPTNNISESYRRYGLTPSKTRDVLVIKIVYPKLSSENSTITSEQQPTPESIWQHLTTHIQGTPVPLTNEELAKSTDWAKVRKYYKLNGVPGVERIDKADEEGRRKEMEGLVISGIALRGL
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Cgi121 acts as an allosteric effector that regulates the t(6)A activity of the complex.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.  Cgi121 is not required for tRNA modification (By similarity).
What are the official names of this protein?
EKC/KEOPS complex subunit cgi121.
What is the protein family that this protein belongs to?
Belongs to the CGI121/TPRKB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: RL14_ACIB3
Sequence: MIQTETMLDVADNSGARRVQCIKVLGGSHRRYASVGDIIKVTVKEAIPRARVKKGDVMNAVVVRTKFGIRRPDGSVIRFDDNAAVILNNNKAPIATRIFGPVTRELRTEQFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL5_PSE14
Sequence: MARLKEIYRKEIAPKLKEELKLSNVMEVPRVTKITLNMGLGEAIGDKKVIEHAVADLEKITGQKVVVTYARKSIAGFKVREGWPIGVKVTLRRDRMYEFLDRLLSISLPRVRDFRGLNAKSFDGRGNYSMGVKEQIIFPEIDYDKIDALRGLDITLTTTAKNDDEGRALLRAFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ERA_STRPZ
Sequence: MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTLIKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNEKEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: ATPD_BUCAP
Sequence: MSVLDTIARPYAKAIFELAIENQSIEKWKKTLIFINEIIRSKKIEKFLSGSLSPSYLSSFFIFVAGDHIDKDARNLIKLLAENQRFKIFNNILRQFLKLETSYQGNTIIELISAYSLQEHEIIDIRCILQKIFLSKIKFIYKIDHQILDGIIIKKADTVFDFSVRSYLKQLSDVLNF
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPOZ_RICAE
Sequence: MARITAEDCNKIIPDRFRLVVLATRYAKLLNYKVETNQIKKEKRDKPPVIALRRIAAGKVSVAQLEQDLINSLRTRTMIEPLVNQDESEAVEEKFEYLPEVYIGEDYSDLDDQIFIDENGEDYETDK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RPOB_BURL3
Sequence: MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADVLAAQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYALSAPAFNIKECQQRGLTYCSALRAKVRLVILDKESPNKPVVKEVKEQEVYMGEMPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMDEGAQLEFVPERLRGEVARFDITDRDGKVIVQKDKRINAKHIRDLEAAKTKFISVPEDYLLGRVLAKNVVDGDTGEVIASANDEVTESVLEKLREAGIKDIQTLYTNDLDQGPYISSTLRVDETTDRTAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEEAYDLSKVGRMKFNRRVSRDEITGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYMIAQANAAIDENGQLIDELVSSREAGETMMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPVVGTGIERTCAVDSGTTVQAFRGGVVDYVDAGRIVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPIVKMGDKVSRGDVLADGASTDLGELALGQNMLIAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGDAFQRLARMLVGKVANGGPKKLAKGTKIDQAYLEDLDHYHWFDIRLADDEAAAQLEAIKNSIEEKRHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPLGVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQAKIEEMRVFLTKIYNDSGRQEDLESFTDEEILELAKNLREGVPFATPVFDGATEEEMGKMLDLAFPDDIAEQLGMNPSKNQVRLYDGRTGEMFERRVTLGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLDRN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CJ090_HUMAN
Sequence: MLKLSGEGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLANRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPALANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDKSLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGACPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFLPIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSPAAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYDNLPEVKKKKEEQRKRVILQSNRLRAEVFKKQLLDQLLQRNAV
What is the function of this protein?
Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage.  Acts as a p53/TP53 activator by inhibiting MDM2 binding to p53/TP53 and stimulating non-proteolytic polyubiquitination of p53/TP53.  Exhibits ubiquitin ligase (E3) activity and assemble ubiquitin polymers through 'Lys-11'- (K11-), 'Lys-29'- (K29-) and 'Lys-63'- (K63)-linkages, independently of the ubiquitin-conjugating enzyme (E2).  Promotes p53/TP53-dependent transcription of CDKN1A/p21, leading to robust checkpoint response.  Mediates CDKN1A/p21 protein stability in a ubiquitin-independent manner.  Interacts with HDAC1 and prevents binding of HDAC1 to CDKN1A/p21 and facilitates the acetylation and stabilization of CDKN1A/p21 (By similarity).  May have a role in the assembly of primary cilia (Probable).
What are the official names of this protein?
(E2-independent) E3 ubiquitin-conjugating enzyme FATS, Centrosomal protein C10orf90, E2/E3 hybrid ubiquitin-protein ligase FATS, Fragile-site associated tumor suppressor homolog, FATS.
Protein: FABZ_DICNV
Sequence: MGIEEIRRYLPHRYPFLLIDRIIALETQNYIHALKNVTANEPFFQGHFPNKAVMPGVLVVEAMAQAAGILGVKSAKAAAGLPDEPEEDGIYFFVGIDKARFRKTVVPGDQLILEVKLLRSRRGIWSFDARATVDDAVVCTAEIMCTSAGKGAA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCP41_ARATH
Sequence: MAIVSLRDVAMVMVTVQVFARGYPETDLVVRLPGQPKVVFRQYAGYVDLDLNAGRSLFYYFVEAEKHPDTKPLTLWLNGGPGCSSVGGGAFTELGPFYPTGYGRGLRINSMSWNKASNLLFVDSPAGVGWSYSNRSSDYNAGDKSAASDMLVFLLRWFDKFPELKSHDLFLTGESYAGHYIPQLADAILSYNSRSSGFKFNIKGIAIGNPLLKLDRDIPAVYEFFWSHGMISEVVGRTIKIQCDFSHYTYAYPHNVSDACNDAIREAGDITTEYVNTFDVLPDLCYPSIALQELRLKQMATKMSMGVDVCMNYERQFYLNIPEVQMALHANRTNLPYSWSLCSNLLNYSAIDVNTNMLPTLKRIIQNKIPVRIFSGDQDSVVPFLGTRTIVGELANDLNFKTTVPYGVWFHKRQVGGWAIEYGNLLTFATVRGAAHAVAYTQPSRALHLFSTFLRGQRLPNKTDIAMHD
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 41.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LSM6_CRYNJ
Sequence: MSSPEPQGEPQPVSGSPSEFLRNIVGKRVKVRIGSGVDYTGLLTCLDGYMNVALEQAEEWAGEVKTAAYGDCFLRGNNVLYISALEDL
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates.  Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.  Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6. U5 tri-snRNP, and free U6 snRNP).  It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm6.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SPTC1_DICDI
Sequence: MFLFDIYNNILYYTKEFIVTSTSPNLFIHGLMAVFIIYLLTKRPFKPRQNDTLTKAEEDELIREWSPIPLTPKSNPLEVLNQTELIIQESEGTHVTINNKKYLNLARSNYLGLINNPEINKISENAIRKYGVGSCGPRGFYGTIDVHLDLEKKTASFMKTPEAVLYSSAYATISSAIPSFSKIGDIIIVDRGVSQPVQVGVSLSRSRIYYFNHNDMDDLQRVLEQTQFKGSKAKIVRKFVVIEGLYYNSGTIAPLPQILKFKEQYKFRLIMDESHSVGVLGSTGRGLTEHYNIDTNLVDILTGSYGNSFSSGGGFCCGSPEVVYHQRLNGVGYVFSASLPPFLACSSTKAIEMLEENPKMLEMLHSNIGELYQGLNKSGALNGLLEITSLPISPVIHLSLLDSKSNKSNRINDELLLQKIVDKAMDYGLLLTRAKYVSAEKFIPKPSIRISVSSNLSSDQIKQSIEIIKKCTSFVLESN
What is the function of this protein?
Component of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmitoyl CoA to form the long chain base 3-ketosphinganine.
What are the official names of this protein?
Serine palmitoyltransferase 1, Long chain base biosynthesis protein 1, LCB 1, Serine-palmitoyl-CoA transferase 1, SPT 1, SPT1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ISPF_SALRD
Sequence: MRIGFGYDVHRLVEGRPLILGGVQVPHDRGLAGHSDADVLLHAVADALLGAAALGDLGAHFPDTDAKWKDADSQALLRRVVERVQHAGYAPHNVDATVLLERPKLRPHVDEMRTNIARALSFPRDAVSVKATTTEGIGFVGREEGVAAQAACTIQSA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RL35_BORHD
Sequence: MSKMKTCKSARKRYAFTSKGKVKYKKQNLRHILTKKSSKRRRKLGKSGLVSSSETKRIKTLLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CTTB2_PONAB
Sequence: MATDGASCEPDLSRAPEDAAGAAAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGDKEKKPVCTNPLSILEAVMAHCKKMQERMSAQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKQVVLMLVKECKQLSGKVIEEAQKLEDVMAKLEEEKKKTNELEEELSTEKRRSTEMEAQMEKQLSEFDTEREQLRAKLNREEAHTTDLKEEIDKMKKMIEQLKRGSDSKPSLSLPRKTKDRRLVSISVGTEGTVTRSVACQTDLVTESADYMKKLPLTMPVKPSTGSPLVSANAKGSVCTSATMARPGIDRQASHGDLIGASVPAFPPPSANKIEENGPSTGSTPDPTSSTPPLPSNAAPPTAQTPGIAPQNSQAPPMHSLHSPCANTSLHPGLNPRIQAARFRFQGNANDPDQNGNTTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAGAPSRPGVPPTGDVGTHPPVGRTSLKTHAVARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIIDSSRASNTGAKVDNKTVASPPSSLPQGNRVINEENLPKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWPAATPGLSQPACSDSSLVIPTTIAFCSSINPVSASSCRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLIAYDANINHAADGGQTPLYLACKNGNKECVKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPARGNSFNEEESESSVFDLDGGEDSPEGISKPVIPADLINHANREGWTAAHIAASKGFKNCLEILCRHRGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIEPSNYGSDDLECENTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDVTCNNTTDSNIGLSARSIRSITLGNVLWSVGQSFVQSPWDFMRKNKAEHITVLLSGPLEGCLSSVTYASMIPLQMMQNYLRLVEQYHNVIFHGPEGSLQDYIVHQLALCLKHRQMAAGFSCEIVRAEVDARFSKEQLLDLFISSACLIPVKQSPSKKKIIIILENLEKSSLSELLRDFLAPLENRSTESPCTFQKGNGISECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFKGQAPSPCDPVCKIVDWALSVWRQLNSCLARLGTPEALLGPKYFLSCPVVPGHAQVTVKWMSKLWNGVIAPRVQEAILSRASVKRQPGFGQTTAKRHPSQGQQAVIKAALSILLNKAVLHGCPLPRAELDQHTADFKGGSFPLSIVSSYNSCNKKKGESGAWRKVNTSPRRKSGRFSLPTWNKPDLSTEGMKNKTVSQLNCNRSASLSKQKSLENDLSLTLNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRMFDSSGNNPVLSATINNLRMPVSQKEVSPLSSHQTTECSNSKSKTELGVSRVKSFLPVPRSKVTQCSQNTKRSSSSSNTRQIEINNNSKEENWNLHKNEHLEKPNK
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: SYDND_HELMI
Sequence: MMIDMFTGLKRSHRGGDLRIDHAGQTVTLMGWVQRRRDHGGLIFVDLRDRSGLVQVVFSPEVGKEAFTKAEDVRNEYVLAVTGDVRPRPEGTVNANLPSGQIDVYARQLWVLNSAKTPPFYIEDGVDVDETVRLKYRYLDLRRPEMQRNLIIRHKTAKAMRDFLDRNGFLEIETPMLTKSTPEGAREFMVPSRIHPGEFFVLPQSPQLYKQILMVAGMERYFQIVRCFRDEDLRADRQPEFTQLDIEMSFTQMDDLLTLMEEMVAHIFKEALGKEISTPFRRIPYAEAMGRFGSDKPDLRFGLELIDLTETVKDVEFKVFASVVKGGGEVKAINAKGCAHFSRKEIDDLTKGVAVYGAKGLAYIQMTEEGPKSPIAKFFTDEQLNAVLDRLGAEKGDLLLFVADKPSVVAASLGFLRQELARRLNLIDSEKLEFAWVVDFPLVEYDPEEKRYNAIHHPFTAPKDEDLDLLDKEPGKVRAKAYDLVLNGVELGGGSLRIYRRDIQEKMFAILGLTAEEAYQKFGFLLDAFDYGTPPHGGIAFGLDRMIMLMTGRDTIRDVIAFPKTQSASDMMVDAPSAVTPRQLKELHIKLDLPVKAPKAEPAKK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_AROAE
Sequence: MPVNLIAVQPSDLLPVPGVRVGVAEAGIRKANRRDLTLIELAAGSRVAGVFTLNRFCAAPVQLCKQHIAGGDVRALVINTGVANAGTGEQGLADAHATCVAVGRTLGVAPEQVLPFSTGVILEALPVDRLIAGLPAAHADLREDGWFDAAHAIMTTDTLAKAVSRQVEIGGRTVTLTGISKGAGMIKPNMATMLGFLACDAAVSQALLDALTKEAADLSFNSITVDGDTSTNDSFIVVATGQAGNAEIADPLGSDFHALRDAVIDVSIRLAQAIVRDGEGATKFMTIAVEGGLDVVECRKVAYAIGQSPLVKTAFFASDPNLGRILAAIGYAGIQDLDVGGLRVWLGTAAEEVLVAELGGRAPTYREEDGVRVMKEAEITVRVDLGRGRARATVWTCDFSYDYVKINADYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRX5_DICDI
Sequence: MNSYLFRIGSKTSGFLRSTQFVRSYSKHVKSESYKKALEDVETQVAESPCILYMKGIPERPECGFSNTAVRILQAEGAVFTSYNVLKNNDMREAVKEFGDWPTIPQLYVKGQFIGGADILMGLYKSGELSKLLNEAGVVKKDE
What is the function of this protein?
Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer (By similarity).  Receives iron-sulfur clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion (By similarity).
What are the official names of this protein?
Monothiol glutaredoxin-5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. Monothiol subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RF1_CAMC1
Sequence: MFADKLHPFLDRYDEISTLLSDPNIANDIEKMTKLSKEQSSIEPVATAATKYLQILNDIEENKALLEDAELGELAKEELKSLEISREKLEEEIKILLLPKDPNDDKNIFLEIRAGTGGDEAALFAGDLFNAYIRYAELRGYKFEIVSQSEGNTGGFKEIIVLIKGKGAYSRLKFEGGTHRVQRVPETESQGRVHTSAVTVAIMPEVEDSEIEINPNDIRVDVMRSSGHGGQSVNTTDSAVRITHIPTGLVVTNQDGKSQHKNKEAAMKVLKARLYEMQEQERLAKETSERKSQVGTGDRSGRIRTYNYPQNRISDHRINLTLYRLDAIMAAGLFDEIIEPLITHYQAEAMLEAGI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF_YERPY
Sequence: MTRIKLSYFTIGLVALLLALALWPNIPWRNGQEGQLDQIKARGELRVSTISSPLIYSTEKDTPSGFDYELAKRFADYLGVKLVIIPHHNIDDLFDALDNDDTDLLAAGLIYNRERLNRARTGPAYYSVSQQLVYRLGSPRPKSFSDLKGQVVVASGSAHMTTLKRLKQTKYPELNWSSSVDKSGKELLEQVAEGKLDYTLGDSATIALLQRIHPQLAVAFDVTDEEPVTWYFKQSDDDSLYAAMLDFYSEMVEDGSLARLEEKYLGHVGSFDYVDTKTFLSAIDNVLPSYQHLFEKHAGDIDWKLLAVIAYQESHWNPQATSPTGVRGLMMLTRATADGLGVKDRVDPEESIRGGAIYLQRLMKKLPETIPEDERIWFALAAYNLGYGHMLDARRLTKNQNGNPDSWVDVKMRLPMLSQKRYYPSTTYGYARGHEAYNYVENIRRYQVSLVGYLQEKEKKAAQHAAIEAELGKSNPVVGPGWSIGD
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: VRAC_STAA1
Sequence: MQHYLLDSNQRLNVSFSKDSVAAYYQCFNQPYRKEVPPLMCASLWPKFDLFKKYANSELILTKSAINQTQKIEVDTIYVGHLEDIECRQTRNITRYTMALTLTKNDQHVITVTQTFIKAMK
What are the official names of this protein?
Protein VraC.
Protein: XERD_CHLTE
Sequence: MPEREEPWRKTLETFLNYLTLERNFSGNTRASYLNDLGRYLAWLHECGVKPEEAAPGDIRKFIQELHEIGLEASSIARNISAIRSFHKFLLTERLATMNPAENIHQPKLARYLPSVLTIEEMATLLDAPLKRHPTSTFMLRDKAMLEFLYATGVRVSELLGLSRLNLHMDDGFVRVFGKGSKERLVPVGQTAISWMKRYLDELRPGMMSATSHDTIFLNSRGGPLSRMAAWNIVREHAVIAGIEKPISPHTFRHSFATHLLEGGADLRVVQEMLGHSSIIATQIYTHIDRSFIKEVHKTFHPRG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELU_ECOLU
Sequence: MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQRWLHEAGIDYPLVDGGYKALRQTAIQATIELSQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQELRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: P33MX_PONAB
Sequence: MASRQPEVPALEASGPLGKMSLPIGIYRRALSYDDTLEDPAPMTPPPSDMGSVPWKPVIPERKYQHLAKVEEGEASLPSPAMTLSSAIDSVDKVPVVKAKATHVIMNSLITKQTQESIQHFERQAGLRDAGYTPHKGLTTEETKYLRVAEALHKLKLQSGEITKEERQPASAQSTPSTTPHSSPKQRSRGWFTSGSSTALPGPNPSTMDSGSGDKDRNLSDKWSLFGPRSLQKYDSGSSTTQAYRGVQKPSPLELIRAQANRMAEDPAALKPPKMDIPVMEGKKQPPRAHNLKPRDLNVLTPTGF
What is the function of this protein?
Potential NADPH-dependent oxidoreductase.  May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth (By similarity).
What are the official names of this protein?
Putative monooxygenase p33MONOX.
What is the protein family that this protein belongs to?
Belongs to the P33MONOX family.
What are the subcellular locations of this protein?
Cytoplasm.