PharMolix/UniProtQA huggingface dataset:
Protein: TRPA_ECO55
Sequence: MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLVALKVFVQPMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: FTO_PONAB
Sequence: MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTMHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDTVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLAPQNVRDDVENDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEAVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDVSMPLPFDLTDIVSELRGQLLEAKP
What is the function of this protein?
RNA demethylase that mediates oxidative demethylation of different RNA species, such as mRNAs, tRNAs and snRNAs, and acts as a regulator of fat mass, adipogenesis and energy homeostasis.  Specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes.  M6A demethylation by FTO affects mRNA expression and stability.  Also able to demethylate m6A in U6 small nuclear RNA (snRNA).  Mediates demethylation of N(6),2'-O-dimethyladenosine cap (m6A(m)), by demethylating the N(6)-methyladenosine at the second transcribed position of mRNAs and U6 snRNA.  Demethylation of m6A(m) in the 5'-cap by FTO affects mRNA stability by promoting susceptibility to decapping.  Also acts as a tRNA demethylase by removing N(1)-methyladenine from various tRNAs.  Has no activity towards 1-methylguanine.  Has no detectable activity towards double-stranded DNA.  Also able to repair alkylated DNA and RNA by oxidative demethylation: demethylates single-stranded RNA containing 3-methyluracil, single-stranded DNA containing 3-methylthymine and has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine.  Ability to repair alkylated DNA and RNA is however unsure in vivo.  Involved in the regulation of fat mass, adipogenesis and body weight, thereby contributing to the regulation of body size and body fat accumulation.  Involved in the regulation of thermogenesis and the control of adipocyte differentiation into brown or white fat cells (By similarity).  Regulates activity of the dopaminergic midbrain circuitry via its ability to demethylate m6A in mRNAs (By similarity).
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase FTO, Fat mass and obesity-associated protein, U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO, U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO, mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO, m6A(m)-demethylase FTO, mRNA N(6)-methyladenosine demethylase FTO, tRNA N1-methyl adenine demethylase FTO.
What is the protein family that this protein belongs to?
Belongs to the fto family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Localizes mainly in the nucleus, where it is able to demethylate N(6)-methyladenosine (m6A) and N(6),2'- O-dimethyladenosine cap (m6A(m)) in U6 small nuclear RNA (snRNA), N(1)- methyladenine from tRNAs and internal m6A in mRNAs. In the cytoplasm, mediates demethylation of m6A and m6A(m) in mRNAs and N(1)- methyladenine from tRNAs.
Protein: BM2_INBLE
Sequence: MLEPLQILSICSFILSALHFMAWTIGHLNQIKRGVNLKIQIRNPNKEAINREVSILRHNYQKEIQAKETMKKILSDNMEVLGDHIVVEGLSTDEIIKMGETVLEVEELQ
What is the function of this protein?
Forms presumably a highly low-pH gated proton-selective channel.  Trp-23 may function as a minimalistic gate that opens and closes the pore.  When the environmental pH is lower than a threshold, the BM2 channel would be activated and selectively transport protons across the membrane from the extracellular side to the cytoplasmic side.  Crucial for the uncoating process.  When the virion is internalized into the endosome, the channel acidifies the virion's interior, promoting the dissociation of matrix protein 1 (M1) from the ribonucleoprotein (RNP) thus allowing the transport of the RNP from the virion into the cell's nucleus.  Also plays a role in viral protein secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation (By similarity).  Plays a crucial role in virion assembly.  Expressed in the late phase of the infection (By similarity).
What are the official names of this protein?
Matrix protein 2, BM2.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type III membrane protein. Host cell membrane; Single-pass type III membrane protein. Note=Transported to the plasma membrane through the trans Golgi network.
Protein: EPIP_STAEP
Sequence: MNKFKFFIVFLILSLVFLQNEYAFGSSLNEELSYYSVEYDNAKTFKESIKQKNIELTYKIPELHTAQIKTSKSKLNSLIKSNKNVKFVNPTCSTCVVEKSVKTGKNLNNKKNGSHDLFDRQWDMRKITNEGKSYKLSPDRKKAKVALVDSGVNSSHTDLKSINKIVNEVPKNGFRGSENDESGNKNFEEDKLNHGTLVAGQIGANGNLKGVNPGVEMNVYRVFGSKKSEMLWVSKGIIDAANDDNDVINVSLGNYLIKDNQNKKKLRDDEKVDYDALQKAINYAQKKGSIVVAAVGNDGINVKKVKEINKKRNLNSKTSKKVYDSPANLNNVMTVGSIDDNDYISEFSNYGNNFIDLMTIGGSYKLLDKYGKDAWLEKGYMQKQSVLSTSSNGRYIYQSGTSLAAPKVSGALALEIDKYQLKDQPETAIELFKKKGIEKEKYMDKKHYGNGKLDVYKLLKE
What is the function of this protein?
Protease which cleaves the matured lantibiotic from the modified prepeptide.
What are the official names of this protein?
Epidermin leader peptide-processing serine protease EpiP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: MGSA_SALPK
Sequence: MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYATGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RNH2_HALMA
Sequence: MRFGVDEAGKGPVLGSMFAAAVRADPAALPGGVGDSKDIRPERRERLAKEIRESADAVGIAEISVERIDADETDMNTLTVEGQAEALSAVARDGLSGTVDAGDTDAARFGRRVADAVDTDVAVTAEHGADETDSLVGAASIIAKVARDTHVAELAAEYGDVGSGYPSDPTTRTFLADYVDRHGELPACARRSWSTCDDVLAAASQSTLSDF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_ECO7I
Sequence: MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCOB_AMYS7
Sequence: MTFAVSVGGRRVDCEPGQTLLEAFLRGGVWMPNSCNQGTCGTCKLQVLSGEVDHGGAPEDTLSAEERASGLALACQARPLADTEVRSTADAGRVTHPLRDLTATVLEVADIARDTRRVLLGLAEPLAFEAGQYVELVVPGSGARRQYSLANTADEDKVLELHVRRVPGGVATDGWLFDGLAAGDRVEATGPLGDFHLPPPDEDDGGPMVLIGGGTGLAPLVGIARTALARHPSREVLLYHGVRGAADLYDLGRFAEIAEEHPGFRFVPVLSDEPDPAYRGGFPTDAFVEDVPSGRGWSGWLCGPPAMVEAGVKAFKRRRMSPRRIHREKFTPAS
What is the function of this protein?
Part of a two-component P450 system that efficiently O-demethylates diverse aromatic substrates such as guaiacol and a wide variety of lignin-derived monomers.  Is likely involved in lignin degradation, allowing Amycolatopsis sp.  ATCC 39116 to catabolize plant biomass.  GcoB transfers electrons from NADH to the cytochrome P450 subunit GcoA.  Highly prefers NADH over NADPH as the electron donor.
What are the official names of this protein?
Aromatic O-demethylase, reductase subunit, NADH--hemoprotein reductase.
Protein: PCYOX_RAT
Sequence: MGRFAATLVGSLFGLGLLLCGLGRLASAEPRAPPEKIAIVGAGIGGTSSAYYLRKKFGKDVKIDVFEREEIGGRLATLKVQGHDYEAGGSVIHPLNLHMKRFVKELGLSSVPASGGLVGVYNGKSLVFEESSWFIINVIKLVWRYGFQSLRMHMWVEDLLDKFMRIYRYQSHDYAFSSVEKLMYAIGGDDYVRLLNQTLRENLKKAGFSETFLNEMIAPVMKVNFGQSTDLNAFVGAVSMTAADSNLWAVEGGNKVVCSGLLQASNSNLISGSVMSIEKTRTKQTGTPPKMYEVVYKTGSEIHSDFYDIVLVAAPLNRKMSNITFRNFDPPIEEFNDPYQQLVTTLIKGELNSTLFSSRHKDQFGLSAILVTDDSDMFINSLSIVASVSHKEGPPPAVDGMHVWKTFSKDILTKEQISKLFLSYDYAVRKPWLSYPYYNPPQKCPSIILHDRLYYLNGIEFAASCMEMSAIAGYNAALLAYHRWNGNEDMIDQDDLYEKLKTEL
What is the function of this protein?
Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (By similarity).  Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides (By similarity).  Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded (By similarity).
What are the official names of this protein?
Prenylcysteine oxidase 1, Chloride ion pump-associated 55 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the prenylcysteine oxidase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: ARGB_METMP
Sequence: MEDYTKAEILIEALPYICKFHDQKILIKYGGHAMVNEQAKNWIAKDLVLLKYVGINPIVVHGGGPEINRAMEKMGKTPEFIHGLRVTDEETLDIVKMVLIGKINGDIVSKLERYGGKSVGLSGKSGQLIKAKKKIQYLMKDSQKIEVDLGMVGEVEHVDTKLIDILVEKRYIPVISPIGVDHQGNDLNLNADIAAGDIAGAMNAQKLIMVTDVDGIMDDVNDPSTLHRRLTIPQIEDMIEKGLITGGMIPKIEACVNALDKGVQSVHIVNGKTPHAVLLEIFTEDGVGTMVVRE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHE10_YEAST
Sequence: MGKLIKLITTLTVLVSLLQYCCEFNSGSISCERTQTLCHYTNPRVWNTYFSRNCELYKNKVSPGFDIVARKYDTAVKPVIDDATVKVNKVAIQPAFKVIHSQCKKWNCGKYYQLVRSPMVKTRRFFFAKYNAFVKPNLDKFFTAEFRSHLKERILKYKNIGHYYFTITSRCIKSKYDFIVGNTEEKLMGKFKNKDTHGIHGSVTREPSSEDMVLTVSTMESDEEELTTTSTQTVVETITLDQEEASAVANHAHDDEASTDVEGSTDVNVNEQALLQEDFDMWSETILQKTQDVIQLFEKDVSKYINGKLVEEANHFKAKFQSLDDKSKKFFSKISLAINDIECVEGIDSETGKKIFFDKSGSTEISQYITRELVREYFNETRSTLDELTNAMEKDLSEITDEIEKKVNAIREENVEVFEEWGDIIVNEWSKRMAYVDVINAHMGADDDTTLDEEKAKSSVNWKKFLKGKKQIIESRDKLAHHSADLSRVNAFRQKVQKKILSFTQESGEFLYILRSKANLQFQERERKERERKEREKAAAEEFQRQQELLRQQEEEDEEDVSYTSTSTITTTITMTL
What is the function of this protein?
Involved in spore wall assembly (PubMed:23966878).  May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria (PubMed:20086051).  Causes growth arrest when highly overexpressed (PubMed:7762298).
What are the official names of this protein?
Outer spore wall assembly protein SHE10, Sensitivity to high expression protein 10.
What is the protein family that this protein belongs to?
Belongs to the OSW/SHE family.
Protein: TRPG_HELPY
Sequence: MKIFFIDNFDSFSYNLVYELECLGYEVAVYQNDIDPSYLMDLMNEESKTPLLFISPGPGNPNSSGNLLKIIAMAKKKFPILGICLGLQALAQSYGAKIIRSKEIVHGKATAIALKKHAVFKGLGESMVVGRYHSLMASGLPKNLEVIAEHDNIPMAIVNEEDKILAYQFHPESIMTLQGRALLEQSVGFLEGLL
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 2, AS, ASII, Anthranilate synthase, GATase component, Anthranilate synthase, glutamine amidotransferase component.
Protein: PURT_XANCB
Sequence: MTTLGTPLSPSATRVLLLGSGELGKEVAIELQRFGVEVIAADRYANAPAMQVAHRSHVLDMLDPQALRALIAQEQPHLIVPEIEAIHTETLVALEHEQGQKVIPTARAARLTMDREGIRRLAAETLGLPTSPYRFVDTAAEYREAIATVGLPCVVKPVMSSSGKGQSTLRSEADIDAAWDYAQTGGRAGAGRCIVEGFIDFDYEITLLTVRHAGGTSFCDPIGHWQKDGDYRESWQPQPMSAAALRRSQEIAQAITDELGGWGLFGVELFVKGDEVWFSEVSPRPHDTGLVTLVSQELSEFALHARAILGLPVGAENGGVIRQSGPSASCALLAHGNGVPVFDNVAEALRDPDTALRLFGKPRVDGHRRVGVTLARAGSIDAAREKARVAAAALTIQLRD
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: UBE2S_DROAN
Sequence: MSSQYSNVENLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGIFRVKLTLNKDFPQTPPKAYFLTKIFHPNVAANGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGKMLLERYDDYSQRARMMTEIHAQPAKCAAGAAGDSKDDDGPSTKKHAGLDKKLQDKKKEKLLKEKKRMLKRL
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.  Acts by specifically elongating polyubiquitin chains initiated by the E2 enzyme vih/UbcH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 S, E2 ubiquitin-conjugating enzyme S, Ubiquitin carrier protein S, Ubiquitin-protein ligase S.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: IOLG_BURVG
Sequence: MTLQIGVIGCGAIGQDHIRRLTRTLSGARVVAVNDIDPQQARDAVTKYGLDAEIYGDGHDVVAAADVQALLVTSWGPTHEAFVLDAIAHGKPVFCEKPLAVTADGCMRIVEAEVAHGKRLVQVGFMRPYDEGYRALKRVIDSGEIGAPLMLHCAHRNQSVGERYTTDMAITDTLIHELDVLRWLLGEDYASAQVVYPKKTRHASAHLADPQIVLLETVSGVRIDVEIFVNCQYGYDIQCEVVGENGIAKLPDPPAVGLKHAARQSVEIMTDWKERFIASYDVELQAFIDGVRAGALTGPSAWDGYAAAVAADACVRAQRSAAVEPIAMAERPAFYRG
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: SYL_PROMA
Sequence: MASKISQTPEKQPSTAYDPLSIETRWQQSWKEQGLYKTKEPTKSQKTFYALSMFPYPSGTLHMGHVRNYVITDVIARLHRMKGDSVLHPMGWDAFGLPAENAAIERGIPADIWTYKNIEDMRNQLNRLGLSIDWDKEVTTCKEEYYKWTQYIFLELYEAGLAYQKSATVNWDPIDKTVLANEQVDANGRSWRSGALVEKKKLKQWFLKITDFADELLEDIELLSGWPQNVKTMQQNWIGRSNGTEIDFYIKGKNNIFITVFTTRPDTLHGTEYLVLAPDHELINSIIDKNKITELEQFRTEISILTDQERTSDGNNKRGMFLGCHAINPINKKIIPIWVGEYVLSSYATGAVMGVPAHDKRDYKFAKKYSLPIQYVIKSPSQEASDLEASSAYVKEGIMINSGEFNGINSKEAGFMITKLGVKQGWAKNKVTYKLRDWLISRQRMWGCPIPIIYCPDCGSVPVKREELPVKLTNPSVIGKSQENKNNIPIMKCSKCNKDSILETDTMDTFMCSSWYFLRYIDVENNKLPFTKTEVDKWLPVDQYVGGIEHAILHLLYSRFLIKALRNRGLLNIKEPFSNLLTQGMVQGVTFKNPKTSKYISPDHINDINTPLDPETGEPLDVLYEKMSKSKYNGVDPASVIDKYGTDTARMFILFKAPPEKDLEWDESDVEGQYRFLNRLWRIVIYSIETKDINISNCTQEILLNDLSDKERKLIKVLNNTIKEVTNDLVNDFQFNTAISELMILCNSIYENIDDCGDYIVTETFKKLTLLLAPFAPHIAEEFWIKLKGKGSVHENSWPTYDPKALLEDSYKLIIQINGKVRGNISVNHEDSELELKNKALACETTQKWLNGIEPKRIIIVKGKIINIVF
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_LIMRD
Sequence: MTLLQNADLMTAIVTPFDDEENIDYGRLEYLTNYLIEHGSNGFVIGGTTGETPELTHDEKIELYQHFGEIVNGRVPVIAGTGSNNTKETIAFTNEVAQINGIDYALVVVPPYNKPNQRGMVAHFTAVADSVDLPIIIYNIPGRTGVKMAQETVVELSHHQNIAAVKQCTSLEELEYIVEHRDPDFAVFTGEDAQALTARVLGANGVISVASHTYVDQMRQMYDSLYRGDYQTAGKLQRWLTPRMAALFMFPSPSPVKAVLNAQGFNVGSCRLPILPLNEEEKRKLETALSLPTNSLTAKNLPLNLGE
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_MYCGA
Sequence: MLKLIKDSLGKFNLTLTDKQIEDIAFFLEEIYHSNQLFNLTGYKTKELIAEMLGVKTILLAQSLSYIFSNQSLNVIDIGTGAGIPGLIIKIIYPQLNVYLVDSNAKKITFINEVIKKLNFTGVFAILSRVEDNFFLKKYHGYFDYVFSQAVSKIAVLNELGTQLLKINGQIIHFKSRDYQEEIEFAKKHLSDLGLAFNNLYHYQFNSYFLVNVFYNKKAIAPQKYPREWSKIKRELIDDAKH
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase, Glucose-inhibited division protein B.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_THEKO
Sequence: MFIVLEGIDGAGKSTQAKLLAEWFENRGYEVVLTKEPTDTPFGKLIRRLVLTGGKEGIIDGAKISHEAEALLFAADRAEHVDKLIKPSLEAGKVVISDRYFYSSLAYQWARGLDLEWLIDLNRFAVKPDIVFLLDLPVKESMNRIRSRKVKSEFDKIFELQRKVRENYLKLAEMFPEMKIINAMEDVETVHNQIIALIETLLGEE
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: YHCT_BACSU
Sequence: MNQKGRGLEILINEKQDGQWLFSVLKTALKASKPVIQDWMSHQQIKVNHESVLNNMIVKKGDRVFIDLQESEASSVIPEYGELDILFEDNHMLIINKPAGIATHPNEDGQTGTLANLIAYHYQINGETCKVRHVHRLDQDTSGAIVFAKHRLAHAILDQQLEKKTLKRTYTAIAEGKLRTKKGTINSPIGRDRSHPTRRRVSPGGQTAVTHFKVMASNAKERLSLVELELETGRTHQIRVHLASLGHPLTGDSLYGGGSKLLNRQALHANKVQAVHPITDELIVAEAPFPADMKNLCRTYFS
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase YhcT, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: H17B1_CYRHA
Sequence: MTTVGVSLFRRSPEKITMKIATFLGLSFLLIASYVLICEAQHPGFQELLILEENMRDPENSKERSCAKPRENCNRMNILCCRGECVCPTFGDCFRYGD
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XVII-2, HNTX-XVII-2.
What is the protein family that this protein belongs to?
Belongs to the hainantoxin family. 17 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_STRP2
Sequence: MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEHYADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGDWGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLMA_MARN8
Sequence: MTNQKPSRRESILQALVELLQSDPGARITTAGLAKTVGVTEAALYRHFPSKRKMFEALIEFAEEAVFSRCQVILQEQEDVRVRLQQLSHLVLVFAERNPGLCCVLTGDALMGEDESLRKRASQFFERLETQIRQALKEGEIRQGLRPRTTAARGADFVMVFVEGRIQRFVRSSFLRLPTSDFDEAWGLVSEAVWG
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YIDD_LIGS1
Sequence: MTILKNQINKGIIFLIRCYQKYISPMFPPTCRYYPTCSNYAIDAIKKHGIVKGIIMGIFRILRCNPFVEGGVDVVPEKFTIFRNDDK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Z280C_HUMAN
Sequence: MDDDKPFQPKNISKMAELFMECEEEELEPWQKKVEETQDEDDDELIFVGEISSSKPAISNILNRGHSSSSSKGIKSEPHSPGIPEIFRTASQRCRDPPSNPVAASPRFHLVSKSSQSSVTVENASKPDFTKNSQVGSDNSSILLFDSTQESLPPSQDIPAIFREGMKNTSYVLKHPSTSKVNSVTPKKPKTSEDVPQINPSTSLPLIGSPPVTSSQVMLSKGTNTSSPYDAGADYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSERPCDEDKTDSETGKLIMLVNEFYYGRHEGVTEKEPKTYTTFKCFSCSKVLKNNIRFMNHMKHHLELEKQNNESWENHTTCQHCYRQYPTPFQLQCHIESTHTPHEFSTICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSSTFSDVEAHFRAAHENTKNLLCPFCLKVSKMATPYMNHYMKHQKKGVHRCPKCRLQFLTSKEKAEHKAQHRTFIKPKELEGLPPGAKVTIRASLGPLQSKLPTAPFGCAPGTSFLQVTPPTSQNTTARNPRKSNASRSKTSKLHATTSTASKVNTSKPRGRIAKSKAKPSYKQKRQRNRKNKMSLALKNIRCRRGIHKCIECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPGKRFCIFKKHSGTLRGITLVCLKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVSKSTSTSEPTTGCSLK
What is the function of this protein?
May function as a transcription factor.
What are the official names of this protein?
Zinc finger protein 280C, Suppressor of hairy wing homolog 3, Zinc finger protein 633.
What are the subcellular locations of this protein?
Nucleus.