PharMolix/UniProtQA huggingface dataset:
Protein: CINES_PICXS
Sequence: MALVSGAPLASRSCLNKSLISSTHELKPLRRTILPTLRWKSATPSINMCLTTSNSVDAVQRRIANHHSNLWDDDFIQSLSTPYEAPSYRERAERLIGEVKEMFESMGPNNDLLQRLSMVESVERLGIDRHFKNEIKSALDYVYSHWNEKGIGCGRDSVVSDLNSTALALRTLRLHGYPVSSDVLEHFKDQKGRFACSSIKTEGEIRSLLNLFRASLVAFPNEKVMEEAEIFSTTYLKEAVQKIPVSSLSRQIEYNMEYGWHTNLPRLEARNYMGDMIHEMSYMNAEKLLELAKLEFNIFHSLQERELKHLSRWWKDSGFSQLNFVRHRHVEYYTLASCIDIDPKHSAFRLGFAKMCHLITVLDDIYDTFGTMDELKLFTAAIKRWDPSATEWLPEYMKGVYMVVYETVNEMAGEAKKSQGRDTINYARQAWEAYIDSYMKEAEWISSGCLPTFEEYYENGKVSFGYQISVLQPILTLDVPLPHHILQEIIFPSRFNGLASGILRLKGDTRCYQADRARGEEASCISCYMNDNPGATEEDALNHIHAMVNELMKEFNWELLKPDNNVPVSSKKHAFDITRAVHHGYKYRDGYSVANNEIKNLVITTVLEPVPL
What is the function of this protein?
Terpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens (PubMed:21385377).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to 1,8-cineole (PubMed:21385377).
What are the official names of this protein?
1,8-cineole synthase, chloroplastic, Terpene synthase TPS-Cin, PgxeTPS-Cin.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ZAPA_ENT38
Sequence: MSAQPVDLQIFGRSLRVNCPPEQRDALSQAADDLNQRLQDLKERTRVTNTEQLVFIAALNISYELTQEKAKTRDYAASMEQRIKMLQQTIEQALLDQGRTPERPGQKFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: MCM10_MOUSE
Sequence: MDVEEDDLCLLTSLLEENEAVLPCSSEKDKSLSLGDGDPDEFDELFDADGDGESYTEEAGSGEEGKTGNQEERLATLFGDVEDLTDDEVATSKVGNSGPPPAPSQEKTSEELQDELKKLQEQMKSLQEQLKAASIKQPPGTAPLQEPPDSSLQPLLKEKRIRRIQESACFSAELDVPTLPKAKRVARKPKTPAESSSRMRTPAQPLQVSSSFLEPNHSSSSRSSTPSPQAVPGNKCSRTIRNQNTVSPGNSGDRPQQVSQVSVEAFSGLRLRRPRVSSTEMSRKMAGRKLIRLPQIKEKMATENLEETDWVTFGVILRKVTPQSATSGQTFSIWKLNDLHDLTQCVSLFLFGDVHKDLWKTEQGTVIGLLNANPMKPKDGLKEVCLSIDHPQKVLIMGEAMDLGACKAKKKNGEPCTQTVNLHDCEYCQYHIQAQYKKLSAKRTDLQSTFSGGRIPKKFRKGTSLKERLCQDGFYYGGVSSESFAASRAAAIAPKKKVQTTLTNLVVRGTNSIIQETKQKLGIPQKSLSCSEEFRELMALPTFGARNLQKHLARAKASGSSKPAIQSISASALLKQQKQQMLEMRKRRSEDIQKRFLQSSSEVQSPAVPSSSRQAAAQSPRTGAEFPRLEGTATPRMPKLGRGISEGDDVLFFDDSPPPRPKLSAAAEAKKLAAIAKLRAKGQILTKVDPNNTVRKQMDGRAMLGVKERVENSNTVSPEEELEPARKKRREQLAYLESEEFQKILKAKSKHTDILKEAEAELQKSYFEPLVKKEQMEEKMRATREVKCRVVTCRTCTYTHFKPLETCVSEQHNLHWHDGVKRFFKCPCGNRTISLDKLPNKHCRNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
What is the function of this protein?
Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.  Additionally, plays a role in preventing DNA damage during replication.  Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability; acts as a direct target of transcriptional repression by ZBTB38 (By similarity).
What are the official names of this protein?
Protein MCM10 homolog.
What is the protein family that this protein belongs to?
Belongs to the MCM10 family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with ORC2 in nuclei foci. Associated with chromatin in S phase (By similarity).
Protein: UPPP_CALS4
Sequence: MKMELLIKAFIMGIVEGLTEFLPISSTGHLIIVGSFIKFTGKFATMFEIVIQLGAILAVVYYFKDKILSSLKALKPGEWGFNLWYKTFIAFLPAAIIGILTHHYIEEHLFSPFTVAIALIVGAIMMIVIEDIFGKKYKIDNMDKVSTSKAFWIGVAQVMSLFPGMSRSASTIMGGMLVGLSVRAAAEFSFFLAIPTMLAATGFELVKNITSMSLLEWEALAVGFIMSFITALIVVDKFLAYLKRHVLKPFAYYRLLVGVLMLFLIAQKIVK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATA_HUMAN
Sequence: MLGRSLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYKNGQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSGGSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDAAIVLGALAGPDPRDSTTVHEPINKPFMLPSLADVSKLCIGIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGLQYGHRCDIDVSTEAMYAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNAFNSGVDVLLTPTTLSEAVPYLEFIKEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEKQVQFPVIQLQELMDDCSAVLENEKLASVSLKQ
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A, Glutaminyl-tRNA synthase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: WCAK_ECOLI
Sequence: MKLLILGNHTCGNRGDSAILRGLLDAINILNPHAEVDVMSRYPVSSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVLRRRYQHQVLLSRVTDTGKLRNIAIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCTFMAKKPLFMIGHSVGPFQDEQFNQLANYVFGHCDALILRESVSFDLMKRSNITTAKVEHGVDTAWLVDHHTEDFTASYAVQHWLDVAAQQKTVAITLRELAPFDKRLGTTQQAYEKAFAGVVNRILDEGYQVIALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLEMGKILGACELTVGTRLHSAIISMNFATPAIAINYEHKSAGIMQQLGLPEMAIDIRHLLDGSLQAMVADTLGQLPALNARLSEAVSRERQTGMQMVQSVLERIGEVK
What are the official names of this protein?
Colanic acid biosynthesis protein WcaK.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide pyruvyl transferase family.
Protein: PROQ_ECOLU
Sequence: MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQKPVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRL_SALPK
Sequence: MTLPSGHPKSRLIKKFTALGPYIREGQCEDNRFFFDCLAVCVNVKPAPEKREFWGWWMELEAQEKRFTYRYQFGLFDKEGNWTVVPINETEVVERLEYTLREFHEKLRDLLISMELALEPSDDFNDEPVKLSA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK2_LAXSS
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, LaxSp-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: I5P1_CANLF
Sequence: MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENFKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYKKVTGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFVRTRWCVADCAFDLVNIHLFHDASNLVAWETSPSVYSGIRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVMLQLEKKLFHYFNQEVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDSGQGRQYMNTRCPAWCDRVLMSPSARELILKSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIAPGAGKPHAHVHKCCVVQ
What is the function of this protein?
Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate (PubMed:8198557).  Plays a crucial role in the survival of cerebellar Purkinje cells (By similarity).
What are the official names of this protein?
Inositol polyphosphate-5-phosphatase A, Type I inositol 1,4,5-trisphosphate 5-phosphatase, 5PTase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cell projection, dendrite.
Protein: NIKR_ECOBW
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: Y2028_VIBC3
Sequence: MAELISIDDTIDTAYDIFLEMAPDNLEPADVILFTAQFDDRGAAELVDVGDDWDDQVGFEVDKEIYAEVRIGLVNEENDVLDDVFARMLISRDPDQKFCHMLWKRD
What are the official names of this protein?
UPF0263 protein VC0395_A0828/VC395_1327.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: NODS_BRADU
Sequence: MTQDENHQLLERELAVDDPWRLDTSAFEQQRYAQMLRMSRRDGDAASALEVGCAAGAFTEMLAPLCERLTVVDVMPQAIERTRLRTGKWSHISWVTCDIQRFSTTEQFDLIVVAEVLYYLRDVVEMHAAIRNLVSMLAPDETLIFGSARDEICQRWGHAAGAETVIALFNESLSEIERRHCCTGSASEDCLIVRFLKPGGASAQSNAGH
What is the function of this protein?
SAM-utilizing methyltransferase involved in nod factor synthesis.
What are the official names of this protein?
Nodulation protein S.
What is the protein family that this protein belongs to?
Belongs to the NodS family.
Protein: RHAT_SALPB
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKQVKQWSWETMWSVGGIVSWLILPWTISALLLPDFWAYYGQFNLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLIHTEGGRMTLLGVFVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLLLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGALVNLGFCFIRLAKVQNLSIKADFSLARPLIISNILLSALGGLMWYLQFFFYAWGHARIPAQYDYMSWMLHMSFYVLCGGLVGLVLKEWKNAGRRPVAVLSLGCVVIIIAANIVGLGMAS
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BIOB_SYNY3
Sequence: MVLASSRPPSPTNSPADRQGTLQAWLTGLSQRIIDGDRLTREEALQLAAIEGEENILLLCEAANRIREACCGNVVDLCSIINVKSGNCSENCGFCSQSSHHPDPNSPIYGLKTEAEILEQARAAAAAGAKRFCLVSQGRGPKYHSPKDREFEQILATVRQIIQETNIKPCCALGEVTPEQAQQLKEAGVTRYNHNLEASATYYDKIVSTHTWQDRVDTVKNLKAAGIQACTGGILGMGETWEDRIDLALALRELEVESVPLNLLNPRPGTPLGEQQKLNPYDALKAIAIFRFILPQQIIRYAGGREAVMGELQDLGLKAGINAMLVGHYLTTLGQPPERDQKLLASLGLEGGEAPIPGEYQS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RUVA_ANAMF
Sequence: MIGTLSGTVEEVVCSNRIILCVGGVGYLVQLPGRVLSGCQHGDHVRLYIETYVGRDGVSQLYGFANREEQNCMRMLIKVSGVNYKTAMAILDVLTPEQVFSAIVSEDRAALKVGGVGEKLISRIISELTPQVQKFELNRFAATTRTDSEAVAALLSLGYERTAALGALQKVGVCDSTEDAVRRALLELSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MLCR_PENCI
Sequence: MSLPHATIPTNLRRRAFRRSCDRCHAQKLKCTGSNANLVRAQCQRCQQAGLRCVYSERLPKRNLHKEAAAGTTRATETSQPMTATSSTVFSSLAETPPPYCSPPTHIGTSALKETLSEPSAATLQFYDTSINFDDPESFPGGWPQPNTFRDDANSNESSGIPDLGYDFEGPLDATAPVSPSLFDLEVEGNSSSGQSNTSNTQRDLFESLSDVSQDLEVILHGVTVEWPKQKILSYPIGDFLNAFGRLLLHLQERVITSSNSSMLDGCLQTKNLFMAVHCYMLSVKIMTSLSQLLLSEVMKAQPCGQKQSTRMDWYWSGSTTRNDNGRAEALPSFHSNLHIGELISHLDPFMHALSSACTTLRVSLRLLSEIETALGIAQEHGAAASIRLVLSDMPSTSWQILGAENKTITPASRLLSVLWSDEAGDEEPKSTKASGKTINVLRRCYKEIFALAKKHNIA
What is the function of this protein?
Transcription factor that regulates the gene cluster that mediates the biosynthesis of compactin, also known as mevastatin or ML-236B, and which acts as a potent competitive inhibitor of HMG-CoA reductase (PubMed:12172803, PubMed:12242508, PubMed:12436257).  Binds to the consensus-binding motif 5'-WCGG-N(6)-TCGG-3' of target genes (PubMed:18667169).
What are the official names of this protein?
Transcription factor mlcR, Compactin biosynthesis protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDPC_BACC4
Sequence: MEKKQSILSPIIRITFTFLVLCGLVYPLIVTGIAQAVMKDNADGSLIYNDKNEVIGSKLIGQNFTDPRYFQGRVSSIEYKAEASGSNNYAPSNPDLAKRVEKSIADWKEKNPAVPVTEIPIDLVTNSGSGLDPDISPKAASVQVDRISKLTNIPKEKLNQLIKDQTEGAALGLFGETRVNVLKLNLALQKLMK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: 3API_HETMG
Sequence: RGICLEPKVVGPCKARIRRFYYDSETGKCTPFIYGGCGGNGNNFETLHACRGICRA
What is the function of this protein?
Serine protease inhibitor that inhibits trypsin (Ki=50 nM) and probably also chymotrypsin (Kd=1. 6 nM).  Has an anti-inflammatory effect in LPS-activated macrophages in vitro, specifically reducing release of TNF and IL6 but not nitric oxide and reducing expression of IL1B precursor.
What are the official names of this protein?
PI-stichotoxin-Hmg3a, PI-SHTX-Hmg3a, Kunitz-type serine protease inhibitor HMRG1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
Protein: HLAB_HUMAN
Sequence: MLVMAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSDVSLTA
What is the function of this protein?
Allele B*67:01: Displays peptides sharing a common signature motif, namely a Pro residue at position 2 and Leu anchor residue at the C-terminus.
What are the official names of this protein?
HLA class I histocompatibility antigen, B alpha chain, Human leukocyte antigen B, HLA-B.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: NADA_SALG2
Sequence: MSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAASTLLVSGVRFMGETAKILSPEKNILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPYAALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHEIQVDAALREGALLPLNRMLDFVATLRA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_TROWT
Sequence: MAKKDGVIELEGSVLEALPNATFRVELSNGHKVLAHISGRMRQHYIRILPEDRVVVELSPYDLARGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADM_PYRHO
Sequence: MIRGLFVGRFQPVHKGHIKALEFVFSQVDEVIIGIGSAQASHTLKNPFTTGERMEMLIRALEEAGFDKRYYLIPLPDINFNAIWVPYVESMVPRFHVVFTGNSLVAQLFKERGYKVVVQPMFKKDILSATEIRRRMIAGEPWEDLVPKSVVEYIKEIKGVERLRNLATNLESSEKELQAPIRVPEY
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFS_CITK8
Sequence: MTFPIEKVRADFPVLTREVNGLPLAYLDSAASAQKPNQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKQASLFINARSAEELVFVRGTTEGINLVANSWGPENVRAGDNIIISEMEHHANIVPWQMLCARTGAELRVIPLNTDGTLQLDTLPSLFDERTRLLAIAHVSNVLGTENPLPEMIALAHQYGAKVLVDGAQAVMHHAVDVQALDCDFYVFSGHKLYGPTGIGVLYVREELLQDMPPWEGGGSMIATVSLTEGTTWTKAPWRFEAGTPNTGGIIGLGAAIEYVCALGLAEISEYEQNLMHYALEQLADVPELTLYGPANRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMTYYNVPAMCRASIAMYNTHEEVDRLATGLKRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_ALIFM
Sequence: MYSLDIIPGKLSLKQLREVSRHPTKLSLDPNALPDMLISADVVAQVIKEDKTVYGINTGFGLLANTRIAEKDLETLQRSIVLSHAAGIGEFMDDATVRLMIILKINSLSRGYSGIRPLVIDALIQLVNSEVYPCIPKKGSVGASGDLAPLAHMSTVLLGEGEARYQDKIISGKEALDIAGLTPITLAPKEGLALLNGTQASTAFALEGLFAAEDLYASATVCGAMSVEAALGSRKPFDPRIHRVRGHRSQMDAALAYRHLLAQSSEIGLSHQCCERVQDPYSLRCQPQVMGACLQQIRNSADILEIEANSVSDNPLVFADDGDIISGGNFHAEPVAMAADNLALAISEIGSLSERRMALLIDSGLSKLPPFLVDNGGVNSGFMIAQVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATFAGRRLGDMAENTRGILAVELLAAAQGLDFRAPNKSSDRIEIAKSLLRERVDFYDKDRYFAPDIAKANSLLKEATYNHLMPETLLPSL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAJ_ECOLI
Sequence: MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMISYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDIRDEAKGNLREQFHFLRSPAPWLIFAATMFGNAGVFAWFSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFNLGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADTPVLAKPLG
What is the function of this protein?
May be involved in either the transport or processing of arabinose polymers.
What are the official names of this protein?
Putative transporter AraJ.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ERA_LEUCK
Sequence: MAESTFKSGFVAIIGRPNVGKSTLLNRIVGEKIAIMSDKAQTTRNKIQGIYTTDNAQVVFIDTPGVHKPQNSLGNFMVKSAFSALHEADAIWFVVDASMPRGRGDDFIISRLNEVTETPIYLLINKVDLIAREELLAIIESYQVDAPTWTEVFPISATEGDNVPELLDNVVSHLDEGPQYFDADQLTDHPERFVIGELIREKVLQLTRQEVPHSVAVVIDKIAREDEEKIHIQASIIVERPTQKNIIIGKQGTMIKNIGTRARKDIERLMGDKVFLETWVKVEPRWRDRPQALQTLGYNEENY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: GATB_STAAS
Sequence: MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAYPGVLPVVNKRAVDWAMRAAMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGENGYIDIEVDGETKRIGITRLHMEEDAGKSTHKGEYSLVDLNRQGTPLIEIVSEPDIRSPKEAYAYLEKLRSIIQYTGVSDVKMEEGSLRCDANISLRPYGQEKFGTKAELKNLNSFNYVRKGLEYEEKRQEEELLNGGEIGQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIVPLYIDDAWKERVRQTIPELPDERKAKYVNELGLPAYDAHVLTLTKEMSDFFESTIEHGADVKLTSNWLMGGVNEYLNKNQVELLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPELAAKGGNAKQIMEDNGLVQISDEATLLKFVNEALDNNEQSVEDYKNGKGKAMGFLVGQIMKASKGQANPQLVNQLLKQELDKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.