PharMolix/UniProtQA huggingface dataset:
Protein: GLNE_RHOPT
Sequence: MIFSAITADLDNTALAARFGAGPRLYDPVLAAERWAGWLVDLAPEQADAIAALGNAFPDLQIALQSIAEASPYLFDLIRGDPVRLLRVLRGAPEQRLAKLLEDAETFVAAASAEDEVMAALRRLKAEAALLIALCDIGGIWPVMQVTQALTDLAGRSVQMALRFLLRLEAGRGRIVPPNPDCPEQGSGLIVLAMGKMGAGELNYSSDIDLIVFYELDAPTLAPDIEPQPFFVRVTQGLSRILQQRRGDGYVFRVDLRLRPDPASTPVALSTVSALDYYEREGRTWERAAMIKARPCAGDLVAGDALLSEIAPFVWRKHLDFAALSDVHDMKRQMQTYRGQTEIAVEGHNVKVGRGGIREIEFFAQTQQLIAGGRHPELRVRPTLEALEILAARNWITIQARDELTEAYLFLRKVEHRVQMIADEQTHALPDTVEAIERFSRFLGYDSRDSFARDLLGYLERVQGHYAKLFEGDPTGTAKLPPVDYGAGPEDTRLLDHLLSLGYKKPLMIATTLQQWMTGGYRVLKVETTQRAFREFVPALIEELARAEQPDDAVNAFDRLLQALHRGGRLISLLSQNRELLTLVALVLGAAPRLGDMLARQPQILDGLIDPRFFGAMPDQAELSARLAVTLADAGSYEEFLDRLRLFGQESLFLIGTRILSGTVPTQQAAVAFADVAEGIVGTVHGLVSEQFASTYGRVKGQQTAILAMGKLGSREMTASSDLDLILIYDFDDDQPDSDGERSLHGAQYFARFTQRLISAFTTRTNYGVLYDVDMRLRPSGRAGPVASRLDAFAAYQEQEAWTWEHLALTRARVISAPPEFRSRIEQVIRAVLTRPRDAAIIANDVAEMRRAIAQEKGEDDVWDLKYAAGGMVDIDFIAQYLQLVHAHEAPDILHVNTLSALDNATRLGLLAQADAEVLRPAARLYQNLTQILRLCVSEKFNPDTAGDDLLRVMVRAGDAPDFSSLQARVKETQSDVRAIFNRLIGGEDA
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: Y782_STAAS
Sequence: MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
What are the official names of this protein?
UPF0337 protein SAS0782.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: EARP_SHEON
Sequence: MSTSSNASHWDIFCTVVDNYGDIGVTWRLAKQLVNEYHIPIILWVDDLNSFSHILPTLNPKLVSQCFNGVIINHWTTPLAVPYLPGKVLIEAFACELPDEVKLQLATLHKTAPQAVPLWLNLEYLSAEDWVDGCHGLPSMQVSGIKKYFYFPGFTPKTGGLICERELFAERDAWQQDPANKLQLFESLGLKDIQAQDSVFSIFSYETDSLPALCELWQARAKNDAKIHALLPKGRSLNSLQHLLPCPVDALMPGQQIKLGDLTLHILPMTDQQGFDRLLWSCDVNIVRGEDSFLRAQWAAKPFIWHIYPQEDDYHLIKLEAFIRLYCDNLAPDIADTWSKLNFAFSQGQQSAVKTHWQNLNPVSLPLLQHAKEWPIDAINAADLATRLVQFVKKS
What is the function of this protein?
Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.
What are the official names of this protein?
Protein-arginine rhamnosyltransferase, EF-P arginine rhamnosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 104 family.
Protein: Y434_ALIFM
Sequence: MNLKNHFLVAMPSMKDPFFQRSVIYICEHDSDGTMGLRINEPVQISLKGMLDQIELDNPSPIIFPQTLSQPVLNGGPVSDDRGFVLHSNKDNYLSSIQVTDELSVTTSKDILATLGTEYQPYKYLVALGYSGWEGGQLEKELSENTWLTLEADPSVIFDTPIPDRWRKALQLLGINPANLSSEIGHA
What are the official names of this protein?
UPF0301 protein VFMJ11_0434.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: YI002_YEAST
Sequence: MTRDTPEDVSTAGAKDILDVLNLLKGGEEKISEVELKLDEMEKKMDSLLVQLEDLHRDNNDLAKSSSQK
What are the official names of this protein?
Uncharacterized protein YIL002W-A.
Protein: RM10_BOVIN
Sequence: MAAAVAGMLRGGLLPQAGRLPTHQFIRYGSKAVTRHRRVMHFERQKLMAVTEYIAPKPVVNPRCLPPPPSPPQEETGLIRLLRREIAAVFRDNRMIAVCQNVAMSAEDKLLMRHQLRKHKILMKVFPNQILKPFLEDSKYQNLLPLFVGHNLLLVSEEPKVKEMVRILKSVPFLPLLGGCIDDTILSRQGFINYSKLPSLALAQGELVGGLTLLTARTHSLLQHHPLQLTALLDQYARQQHEGDPVVPASAQPDPPNPVQDS
What are the official names of this protein?
39S ribosomal protein L10, mitochondrial, L10mt, MRP-L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: COFE_METTH
Sequence: MGISLIGVEGMPLVGAGDDIAYLIISALNEGGEDLLDGDIIVIAETIVSKAEGNIISLEEIKPSPEALDIAERTGKDPSLVEAILGESSEIIRVGHDFIVSETRHGFVCANAGIDESNVDDGLATPLPRDPDGSAEKILRTLQEATGRELAVIISDTQGRPFREGAVGVAVGVAGLSPIWDRKGERDLYGRSLETTRVAVADELAAAASLVMGQADEGVPAVIIRGYPWGHLRSDGGVKPLLRPRELDVFRG
What is the function of this protein?
Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
What are the official names of this protein?
Coenzyme F420:L-glutamate ligase, Coenzyme F420-0:L-glutamate ligase, Coenzyme F420-1:gamma-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the CofE family.
Protein: THIG_BACFN
Sequence: MEKLIIAGREFNSRLFLGTGKFSSNEWMEQSILASGTEMVTVAMKRVDMESTEDDMLKHIVHPHIQLLPNTSGVRNAEEAVFAAQMAREAFGTNWLKLEIHPDPRYLLPDSVETLKATEELVKLGFVVLPYCQADPVLCKQLEEAGAATVMPLGAPIGTNKGLQTKEFLQIIIEQAGIPVVVDAGIGAPSHAAEAMEMGASACLVNTAIAVAGNPIEMAKAFKQAVEAGRTAYEAGLGMQAIGFVAEASSPLTAFLNE
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_SHEPA
Sequence: MTQITLLTPDDWHLHFRDGDMLQETVPATARLFQRAIVMPNLLPPVTDAKMVTEYRERILAARPAGSTFEPLMTIFLTNNTTEQDIIDAKAAGVVAAKLYPAGATTNSDAAVKALDALFPVFEAMAKHGMLLLVHGEVTESHIDIFDREAMFIERYLARIVAAFPTLKVVFEHITTKDAADFVMSAADNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRSTHQEALRAAVATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDDLGALDKLEGFASKHGPDFYGLPRNTSTVTLVKEKWTVPSEIILPNGNPIVPFFAGEEINWKVKTA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: GCH1_RHOP2
Sequence: MDAKIKPLRAGKSADARTDFQPAELDPSEFLAAAVQPDQPRPSRAEAEAAVKTLLSYIGENTEREGLLDTPRRVVEAYDELFQGYHQCPAEVLDRTFGETAGYDDFVLVRDISFTSHCEHHVMPFYGKAHIAYTPVERVVGLSKLARLVEIFARRLQTQEHLTAQIAAAIDEVLKPRGVAVMIEAEHTCMSVRGIGKQGASTFTSRYTGMFRDNPAEQARFMSMIRNRG
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RECF_STRPC
Sequence: MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIYFLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQAKLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQRNSYLKSAQQIDAAFLAVLDEQLASYGARVMEHRIDFINALEKEANTHHQAISNGLESLSLSYQSSVVFDKKTNIYQQFLYQLEKNHQKDFFRKNTSVGPHRDELAFYINGMNANFASQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQTFITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_LACCB
Sequence: MLVPKRVKHRREFRGKMRGAAKGGRNVDFGEYGLEALESHWITNRQIEAARVAMTRYMKRGGKVWIRIFPHKSYTSKGVGVRMGNGKGAPTGWVAVVKREKIMFEVGGVSEAVAKEALRLASNKLPIRTKIVSREEVGGQSNEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: IF4H_MOUSE
Sequence: MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGGSRESRGGWDSRDDFNSGYRDDFLGGRGGSRPGDRRAGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
What is the function of this protein?
Stimulates the RNA helicase activity of EIF4A in the translation initiation complex.  Binds weakly mRNA (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 4H, eIF-4H, Williams-Beuren syndrome chromosomal region 1 protein homolog.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: RPOC_CAUVC
Sequence: MNQEVLNIFNPVQAAPTFDQIRISLASPEKIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPTKDYECLCGKYKRMKYKGIICEKCGVEVTLARVRRERMGHIELASPVAHIWFLKSLPSRIAMMLDMPLKDIERVLYFEYYIVTEPGLTPLKQHQLLSEDDYMRAQEEYGDDSFTAEIGAEAIQNLLKAIDLEKEAERLREELSGTVSDMKQKKFSKRLKILEAFQESGNRPEWMVLTVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQESVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHECGLPKKMALELFKPFIYARLDAKGLSGTVKQSKRMVEREQPQVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILSPANGRPIIVPSQDIVLGLYYLSVARDGEPGEGKIFADLGEIEAAMDAGVVSLHAKIKARHTEMTPEGVLLRKVIDTTPGRMKIAALLPHHPQIGHRLIEKALTKKEIGNLIDIVYRHCGQKATVIFADKVMGLGFKEAAKAGISFGKDDIIIPVRKTAIVEETRKLAEEYEQQYADGLITKGEKYNKVVDAWAKATDRVADEMMAELQMKHKDENGREKEINAIYMMAHSGARGSQAQMKQLGGMRGLMAKPSGEIIETPIVSNFKEGLTVQEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIIVEEDCGTTKGITLRAVVEGGDVLVSLGSRVLGRFTAEDVKDPGTGELVVPADTYIDENIADAIEAAVVQSVKVRSVLTCEAKIGVCGACYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGTAQVAEQSFFEASNEGTVRVIGPTVVGSDGALVIMSRNTSVSVLVDGKERETYKPPYGARLRVKDGDLVKRGQRLGDWDPYTTPIITEVAGKIRAEDLVDGLSIREEVDEATGIAQRVVADWRTSARGSDLRPAMGVLSEDGSYKRLSNGGEARYLLSAGAILSVADGDEVKPGEVIARIPTEGAKTRDITGGLPRVAELFEARRPKDCAVIAEMDGRVEFGKDYKNKRRIKITPDVDADGNQPEAVEFLIPKGKHIAVHDGDYITKGEYIIDGNPDPHDILRILGVEALANFLVDEIQEVYRLQGVPINDKHIETIVRQMLQKVEILEPGDTGLIKGDHLDKPEFDKEQEKAIARGGRPAVTQPVLLGITKASLQTKSFISAASFQETTRVLTEASVHGKTDTLEGLKENVIVGRLIPAGTGSYLRSLQRVAAKRDEQLAQQREDAMEPLPAEIALSDAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: UPP_CAMJE
Sequence: MKNIHCINHPLIEHKLGILRAKETKPFQFRMLIDEISSFLLFEASKDFSLKEIEISTPIQKTTVKKLDEKIMICPILRAALGMLESVFKMIPDASVGFLGFVRNEETLKADFYFQKLPKDAKKRTAIVIDPMFATGGTAIDACNFLKSQGVKKIKFISILAAPQGLKKFSQMHDDVEVFVACIDEGLNEKGYIIPGLGDAGDRVFNTL
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: Y154_PETMO
Sequence: MITLLTKPTVFLITGLSGAGKTLLLQSLEDEGYYTVDNIPPHLIESFLNILCTSNVKKLAIVSDIRWKDPQKLIELFKNVESLAKCTMEIHKVFLKADKSELINRYKKTRRTHPLGLSLENAIDEEIKVMSEIESSCDIVIDTSSTEPTEFKKRFFQMIKEDMKKLKLNFISFGFKNGIPPISDYVFDVRYLPNPFYFPEMYELTGLDMKVMEFLEKFKETHETVDKIANLAKFIQDKYSESGRIEAYFCIGCTGGQHRSVYIAQKVYEILKKEGREVSIDHRDIER
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Pmob_0154.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: KA23K_BUTOS
Sequence: MQKLFIVLLLFCILRLDAEVDGRTMSHCNQSECQEKCKKKNKNGRCITEFEMNYVYNRCRCN
What is the function of this protein?
May block potassium channels.
What are the official names of this protein?
Potassium channel toxin alpha-KTx Tx308.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 23 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SIL1_MOUSE
Sequence: MAPQHLPSTRMASPGMLLGLLLTSCLTLCLSCQNSNNFALTNPEKSIHQESDTKETREEEELDTEILEVFHPTQEWQTLQPGQAVPAGSHVRMNLQTGVNEVKLQQEDKFQNNLKGFKRGRRLDINANTYTSQDLKSALAKFKEGTEMENSKDELARQATVKQLFRPIEELKKEFDELNVVLETDMQIMVRLINKFNSSSSSLEEKVAALFDLEYYVHQMDNAQDLLSFGGLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATNQPLPAKKKVLFALCSLLRHFPYAQQQFLKLGGLQVLRSLVQEKSAKVLAVRVVTLLYDLVTEKMFAEEEAELTQDSSPEKLQQYRQVQLLPGLQEQGWCEITAQLLALPEHDAREKVLQTLGALLTTCRDRYRQDLQLSRTLGRLQAEYQALASLELQEGEDDGYFRELLASINSLMKELR
What is the function of this protein?
Required for protein translocation and folding in the endoplasmic reticulum (ER).  Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.
What are the official names of this protein?
Nucleotide exchange factor SIL1.
What is the protein family that this protein belongs to?
Belongs to the SIL1 family.
Protein: Y039_LYSSC
Sequence: MRGMGNMQGMMKKMQKMQKEMMEAQEALNAEQFEGVAGGGMVKVTVSGQREVVSVNLDESVVDPEDIEMLQDLIVIATNEALKKVEEKTNSTMGKFTQGLNLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Bsph_0039.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HEM1_LEGPA
Sequence: MVFVACGLNHKTAPIHVREKVALQPAMQDSLLSSLLDLPEVNEAAILSTCNRTEIYCDTNTPEVLGNWLAHEHQLSEELLSQFLYIHQGKEGIKHTLRVASGLDSMMIGEPQILGQMKQAYQHACRLGTVKTQLRPVFEYIFRASKRIRTRSGIGANPVSIAYAAVQLIGQLFKNYHSLSVFLIGSGETASLVAKYLHQHGVHRFLIASRTLENAQKLAETFGGKTLSIGDIPQYLPLADVVISATACPLPFINKSLVEHALEQRNHAPMFLLDLAVPRDIEGNVNELEQVHLYNVDDLQSMIEKGMDERRNAALQAEQLIESELDNYIRWHRSLRAKDVICDYRNQMHTLAQQELQRALKKISAGQNQQDVLNEFSMRLVNKLTHNPTIGLRQIAWDNREDLLDLARYLFDTTANQSLYEEIS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ASR_SERP5
Sequence: MKKVLALIVAATMGLSSVAFAADAVAPAAAAPAATTTAAPAAAATKAPAKATHHKKAHKKAPAQKAQAAKKHHKATKKAPAQKAQAAKKHHKATKAAPAQKAQAAKKHHKATKPAAAQKAQAAKKHHKATKKAAPAAK
What is the function of this protein?
Required for growth and/or survival at acidic conditions.
What are the official names of this protein?
Acid shock protein.
What is the protein family that this protein belongs to?
Belongs to the Asr family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MOAA_CLOBM
Sequence: MLDKHGRKINYLRVSVTDRCNLRCVYCMPPEGIVKKEHDNIMRYEEIFKVVKSASLLGVNKIRFTGGEPLILKNIDKLIYNTSKISSIKDIAMTTNAILLEDRVEELKKAGLKRVNISLDSLKEDRFKSITRGGDINKVFKSIEKSLSIGMRPIKINTVIMKGINDDEIDDFMNLTKEYPISIRFIELMPIGEGRKLYKDGYISSEEIISRHSDLIPVETDKSSTALLYKFKESKENIGFISPMSCKFCSGCNRVRLTSEGTLKPCLHSEKEVNLKNYVGNSQALLSKINEAIYNKPLEHHMIEEKESKSKKMMYQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: SPA3M_MOUSE
Sequence: MAFIAALGILMAGICPTVLCFSDDTWGIDILLHKNQESGTPDDSLTLASINTDFAFSLYKKMALKNPDKNIVFSPLSISAALALVSLGAKGNTLEEILEGLKFNLTETSEADIHQGFGHLLQRLSQPEDQDQINIGNAMFIEKDLQILAEFHEKTRALYQTEAFTADFQQPTEATKLINDYVSNQTQGMIKKLISELDDRTLMVLVNYIYFKGKWKISFDPQDTFESEFYLDEKRSVKVPMMKMKFLTTRHFRDEELSCSVLELKYTGNASALFILPDQGRMQQVEASLQPETLRKWWKSLKTRKIGELYLPKFSISTDYNLKDILPELGIKEIFSKQADLSGITGTKDLSVSQVVHKAVLDVAETGTEAAAATGFIFGFRSRRLQTMTVQFNRPFLMVISHTGVQTTLFMAKVTNPK
What are the official names of this protein?
Serine protease inhibitor A3M, Serpin A3M.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_CAUVN
Sequence: MSKLEKLVEELSTLSVLEAAELSKLLEEKWGVSAAAPVAVAAAGGAAAAPAEAAEEQTEFTVVLVDGGDKKINVIKEVRGVRPDLGLKEAKDLVEGAPQNVVENVSKQQAEEISKKLTEAGAKIQIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: YNC3_CAEEL
Sequence: MESPNMRKRLIEMESSLEVKKTATTVKQEPLETSSPLLASMISTAPNPPPTSPHALNYLTLLAAFRQFLHGYIQAGGDENLANTLGNYVAALPMPPNSLNPIGPLNAPKSPFKQQQKFHSIIKAVKREPVSEPAQNAGSGDSSVTLSSALGEDAVPQNRGSCTSMKPVPRFVMLPVVAAQSASPSASGPTSEIQQLREAAFGRYKNVLCVICNEWICSRNRKNHIEAHLNYRPYKCSACSYARRREIFVDQHIRTQHKGVEGVVMLSDVDLHVAMEVDRLAEECVTRTRKIIDTMQEKKDGDFGENKDFDEKALQMMLAEEAENKVVVIESVSQVRPKVANYHRRQRTKVLKKIYDTDVAKQTELKIVKDEEGGVPTMSIKLEEGFEINLEDLMKMVGAGSSITDSNEPGPSEIKKELAEV
What are the official names of this protein?
Putative zinc finger protein R05D3.3.
What are the subcellular locations of this protein?
Nucleus.
Protein: XACH_HALVD
Sequence: MATHDNTEHVSDATDEAVGWESKLRYFLNSDFVRSAPYWGIPFVLMSIAVYGGTGYNFAISFTDYEGLGTPDYSTLDLEMYAQALSSDAFIAAAQNNLVLLVGFTTICLVLGLFLAILLDHGIRFSEKFQTVYLLPMSLSFVVTAQLWLWMFNVESGILNLVVTTLGFNPVDWLGNPSIALGAVILALIWQFSGYTMVVYLAGLQSIPDDQFEAARVDGASITRTYLRIIVPQLKEASVSAAVVLMVFALKAFTFLYALVGRYRPPNGTDILATLMVRRAFKFGEWAYSAAIATMLLIMALGVIGPYLYYQYKQGGL
What is the function of this protein?
Part of the ABC transporter complex XacGHIJK involved in the uptake of xylose and arabinose (PubMed:31089701).  Responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Xylose/arabinose import permease protein XacH.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAE_ACIAD
Sequence: MFIVGLTGGIGSGKSAASQWFEKQGIQVVDADIVAREVVDVGQPALKEIATAFGDWVLQADGSLNRRALREHIFQSPESRHTLEAITHPIIRKSIIEQLNAATSPYVILVSPLLFETNQHELTDRNLLIDASEEIQIARASQRDGQSIQQIQKIIAAQMPRAEKQQRADDIVLNDGHLKHLYQQLIALHENYLNH
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAP4_YEAST
Sequence: MTAKTFLLQASASRPRSNHFKNEHNNIPLAPVPIAPNTNHHNNSSLEFENDGSKKKKKSSLVVRTSKHWVLPPRPRPGRRSSSHNTLPANNTNNILNVGPNSRNSSNNNNNNNIISNRKQASKEKRKIPRHIQTIDEKLINDSNYLAFLKFDDLENEKFHSSASSISSPSYSSPSFSSYRNRKKSEFMDDESCTDVETIAAHNSLLTKNHHIDSSSNVHAPPTKKSKLNDFDLLSLSSTSSSATPVPQLTKDLNMNLNFHKIPHKASFPDSPADFSPADSVSLIRNHSLPTNLQVKDKIEDLNEIKFFNDFEKLEFFNKYAKVNTNNDVNENNDLWNSYLQSMDDTTGKNSGNYQQVDNDDNMSLLNLPILEETVSSGQDDKVEPDEEDIWNYLPSSSSQQEDSSRALKKNTNSEKANIQAKNDETYLFLQDQDESADSHHHDELGSEITLADNKFSYLPPTLEELMEEQDCNNGRSFKNFMFSNDTGIDGSAGTDDDYTKVLKSKKISTSKSNANLYDLNDNNNDATATNELDQSSFIDDLDEDVDFLKVQVF
What is the function of this protein?
Acts a component of the CCAT-binding factor, which is a transcriptional activator and binds to the upstream activation site (UAS2) of the CYC1 gene and other genes involved in mitochondrial electron transport and activates their expression.  Recognizes the sequence 5'-CCAAT-3'.  HAP4 encodes a regulatory subunit of the DNA-bound complex and seems to provide the principal transcriptional activation domains.  Does not bind DNA directly, but augments the binding of HAP2 and HAP3.
What are the official names of this protein?
Transcriptional activator HAP4.
What are the subcellular locations of this protein?
Nucleus.
Protein: APDC_EMENI
Sequence: MIPPKQQTALKITPEGRIAAVSSPLPSLQDNELLVCVKSIALNPFDAKSAEMSPTIGATLGCDFAGKIVATGSNANDFNFSIGDRVCGCVFGNNPNRLDNGAFAEYVAVPADLLLRIPEHMDYNEAATLGVGLATVGMSLYHCLRLPMKPEQAGKSPSGYAAITTCSPHNFNLVKSLGATAAFDYHSPTCGRQIRDFSSGNLWYALDCITDTRSMAVCYEAIGPSGGRYLSLDPFPIRGHTRRSVKPNWVLSVTMYNQPIPWKRPFKRDACPQDLEFAKSWFQIAQRMIDAGEIRPHTSDVKAGGWNGIPGGLELLQKGEVSGRKLVYEVASH
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of aspyridones (PubMed:17369821, PubMed:20828130, Ref. 5).  The polyketide-amino acid backbone preaspyridone A is first assembled by the PKS-NRPS hybrid apdA (PubMed:17369821, PubMed:20828130).  The assembly of preaspyridone A is initiated by loading of malonyl-CoA onto apdA, followed by decarboxylation to yield the acetyl starter unit (PubMed:20828130).  The growing polyketide chain then elongates into a tetraketide (PubMed:20828130).  The adpA PKS module catalyzes three Claisen condensations, as well as beta-keto processing and methylation (PubMed:17369821, PubMed:20828130).  Alpha-methylation step during polyketide synthesis is a prerequisite and a key checkpoint for chain transfer between PKS and NRPS modules (PubMed:25494235).  The downstream NRPS module contains the condensation (C), adenylation (A), and thiolation (T) domains and catalyzes the incorporation of tyrosine via the formation of the L-tyrosinyl-thioester and the amide linkage between L-tyrosinyl-thioester and the tetraketide (PubMed:20828130).  The bimodular assembly line is terminated with a reductase (R) domain that facilitates formation and release of the tetramic acid product (PubMed:20828130).  Because apdA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase apdC (PubMed:17369821, PubMed:20828130, Ref. 5).  ApdC appears to operate with different stereoselectivity in different PKS cycle (Ref. 5).  Combined with apdC, apdA is proposed to synthesize preaspyridone A via about 20 enzymatic steps (PubMed:20828130).  A number of oxidative steps performed successively by the cytochrome P450 monooxygenases apdE and apdB are required for the conversion of preaspyridone A to aspyridone A (PubMed:17369821).  The cytochrome P450 monooxygenase apdE is responsible for the oxidative dephenylation of preaspyridone A (Ref. 5).  Finally, the predicted FAD-dependent monooxygenase apdD and the acyl-CoA dehydrogenase apdG may be involved in the transformation of aspyridone A into aspyridone B (PubMed:17369821) (Probable).
What are the official names of this protein?
Trans-enoyl reductase apdC, Aspyridones biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: ISPG_FUSNN
Sequence: MERNTRVVKVANLKIGGNNPIIIQSMTNTNSADVEATVKQINNLEKVGCQLVRMTINNIKAAEAIKEIKKKVSLPLVADIHFDYRLALLAIKNGIDKLRINPGNIGSDENVKKVVEAAKEKNIPIRIGVNSGSIEKEILEKYGKPCVDALVESAMYHIRLLEKFDFFDIIVSLKSSNVKMMVEAYRKISSLVDYPLHLGVTEAGTKFQGTVKSAIGIGALLVDGIGDTLRVSLTENPVEEIKVAKEILKVLDLSDEGVEIISCPTCGRTEIDLIGLAKQVEEEFRTKKNKFKIAVMGCVVNGPGEAREADYGIAAGRGIGILFKKGEIIKKVSESNLLEELKKMISEDLENKKD
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.