PharMolix/UniProtQA huggingface dataset:
Protein: AIF1_YEAST
Sequence: MTINTKNIVVVGAGVFGVSVANHLYRELGGTYAIKLVTASNYVYFLPSAVRLTVSKDYTKSILPLKNVLDSGIEVIKDTAASFDDKEVVLGSDRAIKFDILVLATGSKWADPIGSTYTFGDNYKEYFEREASRISDADHILFLGGGFVNCELAGELLFKYLEEIRSGKKRISIIHNSDKLLPDSGLYNDTLRKNVTDYLSKNGITLYLNTVGASLDTSPKRIFLGEGSSKYIDADLIYRGVGISPNVPVNSISDLCDKKGFIQVEKNFRVKAVEAGNVFAIGDVTNFRYHGLVKRDNWVDVLTRNVISSLQEGTEASLVDADCLETGHAPSGVSLGPNAGFGQFPLPLLGTINIPSFLISRAKSKNLFSDKMEPLFKK
What is the function of this protein?
Putative FAD-dependent oxidoreductase involved in the resistance to cercosporin and other singlet oxygen-generating photosensitizers.  Translocates from mitochondria to the nucleus under apoptotic conditions, where it degrades DNA and induces apoptosis.
What are the official names of this protein?
Apoptosis-inducing factor 1, Cercosporin and photosensitizer-detoxification protein 1.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Nucleus. Note=Translocates from mitochondrion to the nucleus upon apoptosis induction.
Protein: TYLN_STRFR
Sequence: MRIALLTMGSRGDVQPFVALGTGLRARGHEVVLGAPEALRPLVEQAGLEYRATPGDPDGFFTMPEVVETLRRGPAMRDLMKALPPAPEEYDQEVLDRIERAGEGVDLVVHAPLTVTTALGEPSTPWLSVNWWPNTSTWTFPAVESGQRRMGPLTPLYNRLTHWRAEREDWGWRRAEVNEFRGRRGLPPFGKSSPLRRLGHPRPHLYPFSPSVLPKPRDWPGQCHVTGYWFWDQPGWRPSPELEDFLADGEPPVLLTLGSTWPVHRQEEMVEYAVAAARGARRRLLLVGGPEGALPGDALRVPSADYSWLMPRTAAVVHHGGFGTTADAVRAGVPQVLVPVFADHPFWAARLRRMGTAARPVPLARMNREALAASVRTAVTDPAMAVRARRLGEAVAAERGVENACVLIEEWAETRTTAHTPG
What is the function of this protein?
Involved in the biosynthesis of the macrolide antibiotic tylosin derived from the polyketide lactone tylactone.  Catalyzes the transfer of 6-deoxy-alpha-D-allose from dTDP-6-deoxy-alpha-D-allose to O-mycaminosyltylonolide (OMT) to yield demethyllactenocin.
What are the official names of this protein?
O-mycaminosyltylonolide 6-deoxyallosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
Protein: PRX9_PENRF
Sequence: MNASKLPLGSFVGTTLLLFILYKLVKLAYYVGQAKKTGLPYTLVPVLETEFLGKLLTPLIRPLFTSRLSRGEGWPRWIRFSILDWAWEEKRRVHEELGDVFLLVSPEGLICYTADADMCWDVMNRRNEFLKPRDKYKVLEPYGPNVATTEGKAYNFHVRITAPPFNDGSGANDLVWNEASDQARALMESWSQENTTRDLSLDINRLTLAVISYTGFGKRLDFETEVSDLRNKIPPGYKMSLHHALHLVTTFMVKILLIPKWIMKMTSMKEIAIAHGELEKYMREMIRTETAKLSKDSEYQSADAKGNLLTSVLRASAFEAKAAGRKQAFSEDEVLGNLFLYLLAGYETTANAMTYGFITLALRQDLQDRIIQEVDGVYAEAAAEGRTSLNYTDDFEKFQYTYGFMYEVFRLYPGVCIITKMVPKDTTITVYPENNSPQQHVLPAECRVYLNVNAVHYHERYWPDPWALKPDRWMGTIGVTPNSRPNKKVVAQDKSRQVRGTLMTFSGGARACLGRKFTQSEYISVLATVLGKYRIVLGEGMDAKVVKQEIDHLAAGTVTLAPLKYVKLALKKRTDVKTG
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin (PubMed:24239699, PubMed:27921136).  The first step of the pathway is catalyzed by the aristolochene synthase which performs the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene (PubMed:8440737, PubMed:15186158, PubMed:24239699).  Following the formation of aristolochene, the non-oxygenated aristolochene is converted to the trioxygenated intermediate eremofortin B, via 7-epi-neopetasone (PubMed:24239699, PubMed:26274339).  This conversion appears to involve three enzymes, a hydroxysterol oxidase-like enzyme, the quinone-oxidase prx3 that forms the quinone-type-structure in the bicyclic nucleus of aristolochene with the C8-oxo group and the C-3 hydroxyl group, and the P450 monooxygenase ORF6 that introduces the epoxide at the double bond between carbons 1 and 2 (PubMed:24239699, PubMed:27921136).  No monoxy or dioxy-intermediates have been reported to be released to the broth, so these three early oxidative reactions may be coupled together (PubMed:24239699).  Eremofortin B is further oxidized by another P450 monooxygenase, that introduces a second epoxide between carbons 7 and 11 prior to acetylation to eremofortin A by the acetyltransferase ORF8 (PubMed:16345540, PubMed:24239699, PubMed:27921136).  The second epoxidation may be performed by a second P450 monooxygenase (PubMed:24239699).  After the acetylation step, eremofortin A is converted to eremofortin C and then to PR-toxin (PubMed:24239699).  First the conversion of eremofortin A to eremofortin C proceeds by oxidation of the side chain of the molecule at C-12 and is catalyzed by the short-chain oxidoreductase prx1 (PubMed:16345540, PubMed:24239699).  The cytochrome P450 monooxygenase ORF6 is probably also involved in this step (PubMed:27921136).  The primary alcohol formed at C-12 is finally oxidized by the short-chain alcohol dehydrogenase prx4 that forms PR-toxin (PubMed:16345540, PubMed:24239699).
What are the official names of this protein?
Cytochrome P450 monooxygenase ORF6, PR-toxin biosynthesis cluster protein 6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PETN_HORVU
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y3039_METPP
Sequence: MPSFDTVLEPNLVEVRNAVDQSSKEIGTRFDFKGSSARVELKDKDITLYADSDFQLSQVMDILTLKLTKRSVDARFLDSSAKIEKIGGDKVKQVLKVKEGIDSETAKKIQQLIKASKMKVQAAIQGDAVRVTGAKRDDLQAAMALIRKDVADVPLSFNNFRD
What are the official names of this protein?
UPF0234 protein Mpe_A3039.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: FAR7_YEAST
Sequence: MSDQINVLSMQQQQQQQQQQQQVYMSPQAENLNHMYLLVNKLVKQLRENQAEKAKILRNIDILSGSLNKYETSEEPHDTTENIALFNRFLEQRGKAPITEKEQLSNNLDENAKDDVMLGVLKRQNSMLRKSLQESKQVTLESMDLLSYSEDSLNYIVAQLRGNILMHHKETIKLIRQKFQTETIPLEDEEFKMYLENVNGLQKLTDISHTYRLLLRLHAQD
What is the function of this protein?
Participates in the control of the reentry into the cell cycle following pheromone treatment.
What are the official names of this protein?
Factor arrest protein 7.
Protein: TUSC_ECOBW
Sequence: MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGVFQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHJ_SYNP2
Sequence: MAEENQNPTPEEAAIVEAGAVSQLLTENGFSHESLERDHSGIEIIKVDADLLIPLCTALYAFGFNYLQCQGAYDLGPGKELVSFYHLLKVGDNVTDPEEVRVKVFLPRENPVVPSVYWIWKGADWQERESYDMYGIVYEGHPNLKRILMPEDWIGWPLRKDYVSPDFYELQDAY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J, NDH-1 subunit J, NDH-J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EABN1_BACSU
Sequence: MKKKKTWKRFLHFSSAALAAGLIFTSAAPAEAAFWGASNELLHDPTMIKEGSSWYALGTGLTEERGLRVLKSSDAKNWTVQKSIFTTPLSWWSNYVPNYGQNQWAPDIQYYNGKYWLYYSVSSFGSNTSAIGLASSTSISSGGWKDEGLVIRSTSSNNYNAIDPELTFDKDGNPWLAFGSFWSGIKLTKLDKSTMKPTGSLYSIAARPNNGGALEAPTLTYQNGYYYLMVSFDKCCDGVNSTYKIAYGRSKSITGPYLDKSGKSMLEGGGTILDSGNDQWKGPGGQDIVNGNILVRHAYDANDNGIPKLLINDLNWSSGWPSY
What is the function of this protein?
Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall.  Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1,5-alpha-L-arabinan and of branched sugar beet arabinan.  It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan, wheat arabinoxylan and p-nitrophenyl-alpha-L-arabinofuranoside).  The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substituted.
What are the official names of this protein?
Extracellular endo-alpha-(1->5)-L-arabinanase 1, ABN, Endo-1,5-alpha-L-arabinanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KR194_MOUSE
Sequence: MSYYNSYYGGLGYGSGGYGGLGYGYGCGCGSFRRLGYGCGFGGYGGFGYGSGYGGFSSGSGYGGFGYGYRRPLSYGGYGFSTFY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 19-4, Keratin-associated protein 16-4, Keratin-associated protein 16.4.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 19 family.
Protein: CD81_BOVIN
Sequence: MGVEGCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDRPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAIVDDDANNAKAVVKTFHETLNCCGSNTLMTLTTSVLKNSLCPSSGNVITNLFKEDCHGKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY
What is the function of this protein?
Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling.  Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells.  Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production.  In T cells, facilitates the localization of CD247/CD3 zeta at antigen-induced synapses with B cells, providing for costimulation and polarization toward T helper type 2 phenotype.  Present in MHC class II compartments, may also play a role in antigen presentation (By similarity).  Can act both as positive and negative regulator of homotypic or heterotypic cell-cell fusion processes.  Positively regulates sperm-egg fusion and may be involved in acrosome reaction.  In myoblasts, associates with CD9 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity).  In macrophages, associates with CD9 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (By similarity).  Also prevents the fusion of mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity).  May regulate the compartmentalization of enzymatic activities.  In T cells, defines the subcellular localization of dNTPase SAMHD1 and permits its degradation by the proteasome, thereby controlling intracellular dNTP levels (By similarity).  Also involved in cell adhesion and motility.  Positively regulates integrin-mediated adhesion of macrophages, particularly relevant for the inflammatory response in the lung (By similarity).
What are the official names of this protein?
CD81 antigen.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Associates with CLDN1 and the CLDN1-CD81 complex localizes to the basolateral cell membrane.
Protein: DTXR_CORDW
Sequence: MKDLVDTTEMYLRTIYELEEEGVTPLRARIAERLEQSGPTVSQTVARMERDGLVVVASDRSLQMTPTGRTLATAVMRKHRLAERLLTDIIGLDINKVHDEACRWEHVMSDEVERRLVKVLKDVSRSPFGNPIPGLDELGVGNSDAAAPGTRVIDAATSMPRKVRIVQINEIFQVETDQFTQLLDADIRVGSEVEIVDRDGHITLSHNGKDVELLDDLAHTIRIEEL
What is the function of this protein?
Iron-binding repressor of the dipheteria toxin gene expression.  May serve as a global regulator of gene expression.  Represses ripA under iron excess (By similarity).
What are the official names of this protein?
Diphtheria toxin repressor, Iron-dependent diphtheria tox regulatory element, Tox regulatory factor.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL15_MARHI
Sequence: MRISKPHLRITSIQCYVCLLLNTHFLTEAGIRVFILGCISAGIPKTEANWEDVRKDLQKIENLIQSLHMDATLYTESDVHPRCKVTTMNCFLLELEVISHESRDGDIEETVKNLILLANSSLSSNGNITESGCKVCEELEEKNITEFLESFKHIVQMFINPP
What is the function of this protein?
Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems.  Stimulates the proliferation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines.  In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection.  Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits.  Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5 (By similarity).  In mast cells, induces the rapid tyrosine phosphorylation of STAT6 and thereby controls mast cell survival and release of cytokines such as IL4 (By similarity).
What are the official names of this protein?
Interleukin-15, IL-15.
What is the protein family that this protein belongs to?
Belongs to the IL-15/IL-21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPP_STRPC
Sequence: MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKQNAQQEPAVTDLARMSYKTAFFIGCFQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSLLAIRFLTHYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAL_CLONN
Sequence: MKIFIDTANVEEIKRISKWGILDGATTNPSLIAKEGRQLKEVVEEICSIVDGPISAEVISLNCDAMVKEARDLAKIHKNIVIKIPMCEEGIKAVNILSKEGIRTNVTLIFSPQQALIAAKAGASFVSPFVGRLDDIGMDGVSSIKDIAEIFKIYDIKTEIIAASIRHPMHVLEVAKAGSHIATVPYKVLMQMIKHPLTDIGIEKFLEDYNKSK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ID3_RAT
Sequence: MKALSPVRGCYEAVCCLSERSLAIARGRGKSPSAEEPLSLLDDMNHCYSRLRELVPGVPRGTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELTPELVISKDKRSFCH
What is the function of this protein?
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity.  Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation.  Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation.  Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer.  Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer (By similarity).
What are the official names of this protein?
DNA-binding protein inhibitor ID-3, Inhibitor of DNA binding 3, Inhibitor of differentiation 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSL_DROME
Sequence: MRSWPGLFWLLTLALLADGGRRESQLRIGKAINIFLRYGYLGISMRVIPLNDNSEPDRWVFKEPTKNIYRNLSGLAESHEDTTPGIFHGDFHMEFCENRRQLFQAYFRDFSIERMDKPWEAFTGGWFPDNAAKKLGINTSFIQGDYSYVLVRVVRFRETGRLNAEIPVHQPLEPDVRSRMDQLQIGNITSAVRFMEDVGTHYVNSYTTGNSLYQVFVYSRKNYSMIKERIKSKGLNGLSKLDLYNYFAPWFAAHLGQIRSASANATVERWARRKLQYEYYVVKYVTLLKLHGNSTLLRSLDSLLGNDAILQLDLKSLKPIFREEPEKESWYHEVLDNNVKLWELNMPQSHPTR
What is the function of this protein?
Probable ligand that binds to the torso receptor.  Implicated in a receptor tyrosine kinase signaling pathway that specifies terminal cell fate.
What are the official names of this protein?
Torso-like protein.
What are the subcellular locations of this protein?
Secreted. Note=Is a component of the vitelline membrane (VM, the inner layer of the eggshell).
Protein: HXB8_CHICK
Sequence: YTDCKLAASGLGEEAESSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSR
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B8, Homeobox protein Hox-2.4, Chox-2.4.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HARS1_PONAB
Sequence: MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQSKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKVRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELEDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLCIC
What is the function of this protein?
Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP).  Plays a role in axon guidance.
What are the official names of this protein?
Histidine--tRNA ligase, cytoplasmic, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_BRUA2
Sequence: MAGVNEIRSTFLDYFRKNGHEVVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGLEHRSYNRATTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEDAISFAWNLITREFGLPKDKLLVTVYHTDDDAANFWKKIAGLSDDRIIRIPTSDNFWAMGDTGPCGPCSEIFYDHGDHIWGGPPGSPEEDGDRFIEIWNLVFMQFEQQTPELRIDLPRPSIDTGMGLERIAAVLQGVHDNYDIDLFKALIRASEEATGVKAEGDFRASHRVIADHLRASSFLIADGVLPSNEGRGYVLRRIMRRAMRHAQLLGAKEPLMWRLLPALIREMGQAYPELIRAESLISETLKLEETRFRKTLERGLGLLSDASENLAEGDRLDGETAFKLYDTYGFPLDLTQDALRQRGIAVDTEGFNVAMERQKAEARANWTGSGEAATETIWFGIKDKVGATEFLGYETESAEGVIASLVRDGVEVPSVREGETISVVVNQTPFYGESGGQQGDTGTISGEGFVIAVKDTQKKGEGVFVHIGEVTEGTAKAGDVVELKVDSARRTRIRSNHSATHLLHEALRETLGTHVAQKGSLVAPDRLRFDFSHPKPISAEELEAVENLANEIILQNAPVTTRLMAVDDAIAEGAMALFGEKYGDEVRVVSMGTAKHGSKAGKAYSVELCGGTHVRQTGDIGLVRIISEGGVAAGVRRLEALTGEAARLYLEEQDERVKAIASALKTTSADVLDRVNALIDERKKLERELADARKKLALGGGSSDGGSAVEAVNGVNFLGKIVTGVSPRDLKPLADEGKKQVGSGVVLFIGVGEDGKASAVAAVTEDMVGRFSAVDLVRAASAALGGAGGGGRPDMAQAGGPDGAKAADAIAAVKALIA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_HALLT
Sequence: MSTSDFEERVVTVPLRDANDKPIQERADFAMKIVREHLAQHFSVDEAEVVLDTTVNEAVWANGRQNPPSKVRVRAARFVEDGEPVVEAEYAE
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: RS4_YERPE
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQPPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGANLLQLLEGRLDNVVYRMGFGATRAESRQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAVKMEGVFKRIPERTDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: INSA4_ECOLI
Sequence: MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTYTASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHLKNSGRSR
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element IS1 4 protein InsA, IS1d.
What is the protein family that this protein belongs to?
Belongs to the IS1 elements InsA family.
Protein: ARGB_PROMT
Sequence: MNKEIQQAKHSKNINKPFTDKDSIRVSVLSEALPYIQRFANKRIVIKYGGSAMADKTLQNAVFRDLALLSSVGVQIVVVHGGGPEINQWLEKLGIKPVFLDGLRITDTETMDVVEMVLTGRVNKQIVSGINNHGRLAVGLCGIDGGLIEARTLGGGSHGLVGEVAKVNTKILSPLLEEGYVPVISSVANSSDGKSHNINADTVAGELAAALGAEKLILLTDTPGILRNENDPSSLIEKIRLSEARELIDKGIVKAGMKPKVECCIRSLAQGVNAAHIIDGRTPHSLLLEVFTDAGIGTMVMGRG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.