PharMolix/UniProtQA huggingface dataset:
Protein: SYD_LEUCK
Sequence: MKRTTYAGLVDEKYLNQTVTLSGWVQKRRDFGDLIFVDLRDREGIVQLTFNATHAEALAVAENMRNEYVISVTGQVVRREASQINNKIHSGQIEIDVIEAEILATSKTPPFYIEDNVNANEELKLQYRYLDLRRPEMQKNLRIRSKIMSSAMHFMDQNDFINIETPILAKSTPEGARDYLVPSRIFPGSFYALPQSPQLFKQLLMGSGFDRYFQIARAFRDEDLRGDRQPEFTQMDVETSFMSADEIRELVNAWVKAMMSDVVNFDLDTTKIPTLTWQESMDRFGTDKPDLRIAYELKDVSETVKSSEFGVFAKAVEAGGVVKAIAVPGGAENYSRKDIDKMAQYIERFGAKGLAWLKVTDEGISGPIAKFFPNHAALLQVTGAKPGDLLLFGAGRNDIVAATLDYLRRQTAKDLNLIDMTNPWAFAWIVDWPLFEYSEDFDRWIAAHHPFTMPNEEDLHYLDDGEDPHQAHAQSYDLVLNGYELGSGSIRIHRMDIQEKMLKALGFTPEAAHEAFGFLLEGMTFGFPPMGGIALGLDRLAMLLAGQENIREVIAFPKNSRATEPMTQAPTRVDHKQVNDLGLFVSDVE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_MYCBT
Sequence: MTAATKATEYPSAVAKARFVRVSPRKARRVIDLVRGRSVSDALDILRWAPQAASGPVAKVIASAAANAQNNGGLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVESRPAKDQRSAKSSRARRTEASKAASKVGATAPAKKAAAKAPAKKAPASSGVKKTPAKKAPAKKAPAKASETSAAKGGSD
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: EOLA1_HUMAN
Sequence: MKFGCLSFRQPYAGFVLNGIKTVETRWRPLLSSQRNCTIAVHIAHRDWEGDAWRELLVERLGMTPAQIQALLRKGEKFGRGVIAGLVDIGETLQCPEDLTPDEVVELENQAVLTNLKQKYLTVISNPRWLLEPIPRKGGKDVFQVDIPEHLIPLGHEV
What is the function of this protein?
May play a role in cell protection during the inflammatory response.  In epithelial cells, negatively regulates IL6 production and apoptosis through the regulation of MT2A expression (PubMed:24916366).
What are the official names of this protein?
Protein EOLA1, Endothelial-overexpressed lipopolysaccharide-associated factor 1, Endothelium and lymphocyte associated ASCH domain 1.
What is the protein family that this protein belongs to?
Belongs to the EOLA family.
Protein: F171B_HUMAN
Sequence: MARLCRRVPCTLLLGLAVVLLKARLVPAAARAELSRSDLSLIQQQQQQQQQQQQQQKQLEEAEEERTEVPGATSTLTVPVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFENIELTPLAAICVKIYSGGKELKVNGSIQVSLPLLRLNDISAGDRIPAWTFDMNTGAWVNHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRGSGINEDSKDITAYHTVFLTAILGGTIVIVIGFFAVLLCYCRDKCGTPQKRERNITKLEVLKRDQTTSTTHINHISTVKVALKAEDKSQLFNAKNSSYSPQKKEPSKAETEERVSMVKTRDDFKIYNEDVSFLSVNQNNYSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPEQLMHIYSQPIAILQTSDLFSTPEQLHTAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPIHSHAQPPDAREEDIILEGQQSLPSQASDWSRYSSSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNELHSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGSGVIMEHPGEESPGRKSTVEDFEANTSPTKRRGRPPLAKRDSKTNIWKKREERPLIPIN
What are the official names of this protein?
Protein FAM171B.
What is the protein family that this protein belongs to?
Belongs to the FAM171 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MTNA_PARBD
Sequence: MPLIAISYSHGKLSILNQLFLPHQTTYDPIYSACDAWHAIHDMRVRGAPAIAIVAALSLAVELYDLIQKGKLSDQAKEVEIFIREKLEYIASSRPTAVNLVEAAGRLGKIVVARSCGEGVTGREVAEEYIRAAEKMLEDDVKDNRGIGEFGAKWIMKQAIDGAEGKGKVAVLTHCNTGSLATAGYGTALGVIRSLHAANSLKHAYCTETRPYNQGSRLTAYELVHDNIPATLITDSMAAALLAHKSAGVGAIVVGADRVAANGDTANKIGTYGLAVLAKHHGVKFLVAAPRTTIDMNTKSGEGIAIEERPRQEMTRIRGPRVGGEQDGLGAMETITVAADGIDVWNPAFDVTPASLIDGIITEIGVVEKDRDGEFHLERVFE
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1979_PARP8
Sequence: MIIVLSPAKSLDYETPPHVKKHTIPDFVDDAAELIGGLRRLSPQDIASLMDISDQLAHLNFQRYADWSPTFDSSNSKQAVLAFNGDVYEGFDAKSLSASDLDYAQQHVRVLSGLYGLLRPLDLLQPYRLEMGTRFENSRGKDLYAFWGARITQALNQQLEKKKGGSRVLINCASTEYFKSVKPKQLSAPVITPVFEDWKGGRYKIISFHAKRARGLMARYLVENRFDTPEQMKAFDSEGYAFDAQASNDSTYVFRRRVAD
What are the official names of this protein?
UPF0246 protein Bphy_1979.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: ESR2_ANGJA
Sequence: MAGSPGNELPLLQLQEVDSSKVGESGGSSGLLPTMYNGALPALSMESHAVCIPSPYTDSSHDYAALTFYSPPILSHGGPAVPESPAARQSLSPSLFWPAHGHHGHVSPLALHFQQPLVYREPAHSPWAEPKPLEHGQAQTSKLAGKRMAESEEGTSSVGGCFAGKGDMHFCAVCHDYASGYHYGVWSCEGCKAFFKRSIQGHNGYICPATNQCTIDKNRRKSCQACRLRKCYEVGMMKCGVRRERCTYRGARHRRMPHIRELAGTGGGARTQRRGEGVVPQTQEAQSSALTPEQLINRIIEAEPPEIYLMKELKKPFTEDSMMMSLTNLADKELVLMISWAKKIPGFVELDLSDQVHLLECCWLEVLMLGLMWRSVDHPGKLIFSPDLKLNRDEGSCVEGILEIFDMVLAATSRFRELKLQREEYVCLKAIILLNPNLCTTSSENREELESRNKLLHMLDSVTDALVWTIAKKGLTFQQQSARLAHLLMLLAHIRHLSNKGMEHLSNMKRKNVVPLYDLLLEMLDANTMHSSRMSASYSSQPSPWSQAAQSQPGPPPSCSGECPCPPKESSTI
What is the function of this protein?
Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
What are the official names of this protein?
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRD_ENT38
Sequence: MYYPFVRKALFQLDPERAHELTFQQLRRITGTPLEALVRQKVQEKPVQCMGLTFKNPLGLAAGLDKNGECIDALGAMGFGSIEVGTVTPRPQAGNDKPRLFRLVEAEGLINRMGFNNHGVDHLIENVKKAHFDGVLGINIGKNKDTPVEQGKDDYLICMEKVYAYAGYIAVNISSPNTPGLRTLQYGEALDDLLSAIKNKQNELQEIHHKYVPVAVKIAPDLSVEELIQVADSLVRHNIDGVIATNTTLDRSLVNGMKHCDEMGGLSGRPVQLKSTEIIRALSAELKGRLPIIGVGGIDSVIAAREKMAAGATLVQIYSGFIFKGPQLIKEIVNHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ISPF_GEOSL
Sequence: MRIGHGYDVHRLVAGRKLIVGGVDIPHELGLLGHSDADVLLHAISDAILGALALGDIGKHFPDTDPRYKGADSRALLRHVMELATRKGFHLGNLDATIVAQRPKMAPHIPLMREHIAADLMADPDRVNVKATTTEELGFAGRGEGIAAYAVVLMEEK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: BPS1_ANAPL
Sequence: QKKGFCAGYCSYSCAKTDEWTFHQTCGKMYCCIPPPKKG
What are the official names of this protein?
Small basic protein 1, Basic protein small 1, dBPS1.
What is the protein family that this protein belongs to?
Belongs to the transferrin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PONF_DICDI
Sequence: MKFIPALIIFVFTIFALTNSETTYSGFKITSADPKNPCSISVPQTDVGTKCIDVCGQGNINIAAVSGETNKYDINGYQATDQCKNSAGQQTLTCGTPVTVGVFSIDCAPDAGATTAAVTTAATTAAVTTAATTAAVTTASTTAAFTTTGTSSTIVIPFALILSLLLSVITL
What are the official names of this protein?
Ponticulin-like protein F.
What is the protein family that this protein belongs to?
Belongs to the ponticulin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: LPXK_LEGPC
Sequence: MSFFVNRIWYGNHFLQWILVPFSWLYRIVIRTRRWYLQRFCQQLYPIPIIVVGNVTVGGVGKTPLVIEIAKKIQQKGLKVGIVSRGYKAAIKHFPYEVKLNDSAELVGDEPLMMARKINCPVVIAPKRNEAVRYLLDKHSVEIIISDDGLQHYKMGRSIEIVVIDGMRKLGNGFCLPAGPLREPDSRLKQVDFVIVNQGAAEGTYSMELIPKNIVRLSTQEEVSNDLFTSEVAAVAGIGNPQRFYSTLSQLGIKFNPYSYPDHHQFKPHDLNDIDLPVIMTEKDAVKCYSFSSDKLYYLPVEAKLNDSFWEAFWSHQQLQGYY
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: GUAC_TOLAT
Sequence: MRIEEDLKLGFKDVLFRPKRSTLSSRSQVELHREFRFRHTQTSWRGVPIIAANMDTVGTFAMAKALASFDVMTAIHKHYTEQEWQTFVQNSSDPLLQYCMVSTGTSNNDFLKLQRILALSPALRFICVDVANGYSEHFADFVKIVRETFPQHVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAIIECADAAHGLGGQIVGDGGCTCPGDVAKAFGGGADFVMLGGMLAAHEESGGNKFERDGKTFMRFYGMSSSTAMEQHAGGIAHYRASEGKTVELPFRGPVSATIQDILGGVRSTCTYVGAAKLKELTKRTTFIRVSEQENPVYGQE
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: AT391_HYAAE
Sequence: MVKCTPLLALTVIVSAGSDALSDPTVKRLAKLATINQAPATQSNSDSKRVLRASDVPDEVAAGESRSPKSLWPWEVEDKLAPLKEKLISTSADDLEAGGSANKNALPMIWRWLWQNQIETKKTPIDEISKEVQTAMDLISSQATHEELNKAGVSVSDYVKALRFTLSDIDVVNRGMEYNIHLGNK
What is the function of this protein?
Secreted effector that acts as an elicitor of hypersensitive response (HR) specifically on plants carrying defense protein RPP39 (PubMed:22359513).  The allele ATR39-1 is recognized by RPP39, whereas the ATR39-2 allele is not recognized (PubMed:22359513).
What are the official names of this protein?
Avirulence protein ATR39-1, Arabidopsis thaliana recognized protein 39-1.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: LEUC_ALIF1
Sequence: MSNAKTLYEKIYDAHVAVAAEGENPILYIDRHLVHEVTSPQAFDGLREKGRKVRQVGKTFATMDHNVSTQTKDINASGEMARIQMETLSKNCEEFGVTLYDLNHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQARAKTMKIDVKGKVAEGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLTMEGRMTVCNMAIELGAKAGLIAPDQTTFDYIAGRKFSPQDADLDAAIEYWSSLKTDDDAEFDAVVTLDASEIKPQVTWGTNPGQVIAVDAPIPAPESFADPVEKASAEKALAYMGLEAGKSLSDYNVDKVFVGSCTNSRIEDMRAAAAIAKGRKVASHVQALIVPGSEQVKAQAEKEGLDVIFKEAGFEWRLPGCSMCLAMNNDRLGPHERCASTSNRNFEGRQGRDGRTHLVSPAMAAAAAIAGHFVDIRTITEQA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: BIOH_BUCBP
Sequence: MNKKLHWKSLGTGTTNLILIHGWGVNSKIWSILVQSQLYQHFKLHFVDLPGFGHSNQLLPMTLNDTAELLSVYIPKNSILLGWSMGGLIASKIALNYPQKIKGIISVCSSPCFIVRPNWPGIPKKIFLKFYNKLNINFDRTISEFITLQSHNTNYLEIKNLKQQILSQPYPTIYTLKKNLETIFKTDLRTKIKKLKIPMLRIYGSLDTFVPKKIREILDILWPKTKSITIAHASHIPFVSHQKEFYESIINFKNYLNTLKITCQK
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIA_CALS4
Sequence: MCRVFMIAGTHSGAGKTTLSLGIMGVLSKKYNVRPFKVGPDYIDTAYHRYVTRNFSVNLDLFMLGEENLKNLFYKNASRADVSIIEGVMGLYDGIDTTSRGSSAHIAKLVNVPVVLVVDASSMAASVSALIMGYIYYDKDVDIRGVILNKVGSERHYTLLKEVIERDLNIEVFGYLPKDVELELPERHLGLLPVYETENLDKKLEKLYGYIENCIDVEKLMNLTVKPPDFIEKEDRVLKEKKVKIAYAYDEAFNFYYKESLETLEEMGAHLIPFSPLDDERLPEGTEGLYIGGGFPEVFAKRLSENESMLREIKEAVEKGMPVYAECGGLMYLSKGIRDLEGNRYSMVGVYDFEVVMTKKLQRFGYVEAEITMDNVLFKKGERIKGHEFHYSRIEGFSQNASYIVNRPGKEEKWECGFVHKNCLASFVHINLYTYKEGVKRFLDRCSSFGRK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: PHNC3_HALH5
Sequence: MIEFKNVSLVYPNGTQGLKDVNLKINEGEFVVIVGLSGAGKSTLIRSMNRLVTPTEGELLIDGENILPYSSRQLRKLRTKVGMIFQNYNLVKRSSVMKNVISGRLGHVGTFASLLNLYPKEDVALAYRSLQRVNIAEKVYQRADQLSGGQQQRVAIARVLTQQPKIILADEPVASLDPPTSHQVMTYLRKINKEDKITTIVNLHFIDMAMEYADRIIGMRAGEVVFDGPASDVSEETFEEIYGRKIREDDLVGGQDNE
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
Protein: HYDN_ECOLI
Sequence: MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRIHVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYGAMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKLEQLSAEKRRRTALMF
What is the function of this protein?
Electron transport from formate to hydrogen.
What are the official names of this protein?
Electron transport protein HydN.
Protein: VATE_ACET2
Sequence: MAGVEKIKERILEEARAQAEANIKRAEEEAAKIIEEAQKEAAAKKAQILEKAKQEAVDVKKRLKAMAELEARKKKLQARQEVVDEAFNKTIEKLNSLPDREYEEIISQMIVNSVESGSEEIILSPKDKQRISPGFIENINKKLSQKGIDGKIKLSEETKNISGGFILKSGDIEINNSFEAIIRMKREEVEAEVIKALF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: CH60_FUSNP
Sequence: MAKIINFNDEARKKLEIGVNTLADAVKVTLGPRGRNVVLEKSYGAPLITNDGVTIAKEIELEDPFENMGAALVKEVAIKSNDVAGDGTTTATILAQAIVKEGLKMLSAGANPIFLKKGIELAAKEAIDVLKDKAKKIESNEEISQVASISAGDEEIGKLIAQAMAKVGETGVITVEEAKSLETTLETVEGMQFDKGYVSPYMVTDSERMTAELDNPLILLTDKKISSMKELLPLLEQTVQMSKPVLIVADDIEGEALTTLVINKLRGTLNVVAVKAPAFGDRRKAILEDIAILTGGEVISEEKGMKLEEATIQQLGKAKTVKVTKDLTVIVDGGGEQKDISARVNSIKAQIEETTSDYDKEKLQERLAKLSGGVAVIKVGAATEVEMKDKKLRIEDALNATRAAVEEGIVAGGGTILLDIIESMKDFNETGEIAMGIEIVKRALEAPIKQIAENCGLNGGVVLEKVRMSPKGFGFDAKNEKYVNMIECGIIDPAKVTRAAIQNSTSVASLLLTTEVVIANKKEEEKAPMGAGGMMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_WOLSU
Sequence: MKTIAIIGKPNVGKSSLFNRLAKERIAITSDVSGTTRDIKKQVIEIEGNEVLLVDTGGIELKETGLFGKVRELALRAAKEADVVLYMVDGKMRPQDDDISLFRALHRENEHLFLVVNKIDNDKEKERGWEFAEFGAEKLLFISVSHNRGVGALQREIADVLGLEAPQEIVLSEDDEEDLEEYLVSLEEEEIEEIEEAPSEIRVGIIGKVNVGKSSLLNALLGSERSVVSDVAGTTIDPVDESMEIEGQKVLFVDTAGIRRRGKIEGIEKYALDRTQKALEKADIALLVLDCSLPFADLDEKIGGLVDKFSLGVIVVLNKWDIRSREFKEVEKEVRHRFKYLEHAPLVTVSAQNGRHIDMLKEKILKVYENFSRRIPTSILNKTIMEASARHPLPSDHGKIVRIYYATQYGVCPPQISLVMNRPNSLHFSYKRYVVNFLRDRFDFEGSPILIRARKRGEKLQDEIEALGED
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL23_MARMM
Sequence: MSAAARHYDTILSPVITEKSTLLSEESKVVFFVPLSANKGEIAEAVEALFKVKVTAVNTIKVHGKTKRFRGIPGRRNDQKKAVVTLAEGHSIDVTTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: FMT_STRPN
Sequence: MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKVIQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMDFAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDEDNVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTNRQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGALSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GUAA_CHLL3
Sequence: MQSVLVLDFGSQYTQLIARRIRELGIYSEILPYSTTPEAIREHDPKAIILSGGPTSVYGESAILPHPGIFSLGLPILGICYGLQAIANHFGGAVESSSKQEFGRAKILVDRTEGHESMLFKDIPDSDVWMSHGDKVTRMPEGFQITASSGNSEMCAIESFGPKAALKIYGLQFHPEVQHTLYGKQLLSNFLINIAGIRPDWSSKSFIEHQIEDIRQRADKGTVICGISGGVDSTVAAVLVSKAIGKQLHCVFVDNGLLRKNEARKVMEFLKPLGLNITLADSADLFLGRLKGVASPEKKRKIIGRTFIRVFEEHINEEKFLVQGTLYPDVIESQSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIPEDILMRHPFPGPGLAVRVLGSLTRERLDILREADEIYIDELKSSGLYQQVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESTDGMTADWAHLPHDFLAKVSNRIINEVRGINRVAYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DBP3_CANAL
Sequence: MSFSSGKFLFVFLFFFFFKNTSCSNQRKYITKQQTMSKDKKEHKDKKRKHDNEDVEIADSKKQRKLEKQEKKDKKDKKDKKEKKEKKEKKHKKEKKHKDSESSPVEPAANDSSSSTNYTQSSKLSSVSQSDIDKFLSDNEITVEDPSSSSLRPILSFDQVQLTSAITSKLSKFDKPTPIQSVSWPFLLSGKDVIGVAETGSGKTFAFGVPAINNIITTGNTKTLSVLCISPTRELALQIYDNLIELTADSGVNCVAVYGGVSKDDQIRKIKTANVVVATPGRLVDLINDGAINLGKVNYLVLDEADRMLEKGFEEDIKTIISNTSNSERQTLMFTATWPKEVRELANNFMNSPVKVTVGDRDELSANKRITQVVEVINKFDKEKKLIQLLRKYNANESSDNKILIFALYKKEASRIENFLKRNRFSVAAIHGDLSQQQRTAALSAFKSGQSNLLLATDVAARGLDIPNVKVVINLTFPLTIEDYVHRIGRTGRAGAKGTAHTLFTEDEKHLSGALCNILRGANQPVPEELLKFGGHTKKKAHSVYGAFYKDVDMTKTAKKIKFD
What is the function of this protein?
ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis.  Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ATTB_HYACE
Sequence: MFAKLFLVSVLLVGVNSRYVLVEEPGYYDKQYEEQPQQWVNSRVRRQAGALTINSDGTSGAVVKVPITGNENHKFSALGSVDLTNQMKLGAATAGLAYDNVNGHGATLTKTHIPGFGDKMTAAGKVNLFHNDNHDFSAKAFATKNMPNIPQVPNFNTVGAGVDYMFKDKIGASANAAHTDFINRNDYSLGGKLNLFKTPTTSLDFNAGWKKFDTPFFKSSWEPSTSFSFSKYF
What is the function of this protein?
Hemolymph antibacterial protein.
What are the official names of this protein?
Attacin-B, Immune protein P5.
What is the protein family that this protein belongs to?
Belongs to the attacin/sarcotoxin-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROQ_YERPE
Sequence: MENQPKLNSSKEVIAFLAERFPLCFTAEGEARPLKIGIFQDLVERVQGEENLSKTQLRSALRLYTSSWRYLYGVKVGAERVDLDGNPCGVLEEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAIAAGETPEPRRPRPAGKKPAPRREAGAAPENRKPRQSPRPQQVRPPRPQVEENQPRPVPVTDISKLQIGQEIKVRAGKSAMDATVLEIAKDGVRVQLSSGLAMIVRAEHLQF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_ENTFA
Sequence: MADDRKVALDAALKKIEKNFGKGSIMKLGEKADQKISTIPSGSLALDVALGVGGYPRGRIIEVYGPESSGKTTVSLHAIAEVQRNGGTAAFIDAEHALDPQYAEKLGVNIDELLLSQPDTGEQGLEIADALVSSGAIDIVVIDSVAALVPRAEIDGEMGASHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPETTPGGRALKFYATVRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKVAEVDIMYGQGISQEGELLDMAVEKDLISKSGAWYGYKEERIGQGRENAKQYMADHPEMMAEVSKLVRDAYGIGDGSTITEEAEGQEELPLDE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YA70_HELPJ
Sequence: MRSCKQIFDKGLKPYYKHSVCLKPFFRFCFLKIHAYQQRYRAFALTLFSCKFFNACKIFIPIIDFKIVFIPILKHQAKLKRVSNAY
What are the official names of this protein?
Uncharacterized protein jhp_0355.
Protein: MRAY_FLAPJ
Sequence: MLYYLFQYLDKYFDFPGAGVFQYITFRSALAIIMSLLISTIFGKRVISYLSRLQVGETVRELGLEGQTQKAGTPTMGGLIIIFSTLLPVLLLAKLNNIYIILLIVTTIWMGAIGFLDDYIKIFKKDKAGLKGIFKVIGQVGLGLIVGTTLYFHQDVTIRENISKNKIEVYSTQKGANTLSSDKKSTATTIPFFKNNEFDYAELLAWTGDGYRNYAWLIFIPIVIFIITAVSNGANLTDGIDGLAAGTSAISVIAIGVFTFVSGNVIFSNYLNIMFIPNSGEMTVFIAAFVGALIGFLWYNSYPAAVFMGDTGSLTIGGIIAVLAIAVRKEMLIPVFCGIFLAENLSVVLQVSYFKYTKKRFGEGRRIFLMSPLHHHYQKKGYHESKIVTRFWIVGILLAIVSIVTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.