PharMolix/UniProtQA huggingface dataset:
Protein: APOE_MACMU
Sequence: MKVLWAALLVTFLAGCQAKVEQPVEPETEPELRQQAEGQSGQPWELALGRFWDYLRWVQTLSEQVQEELLSPQVTQELTTLMDETMKELKAYKSELEEQLSPVAEETRARLSKELQAAQARLGADMEDVRSRLVQYRSEVQAMLGQSTEELRARLASHLRKLRKRLLRDADDLQKRLARLGPLVEQGRVRAATVGSLASQPLQERAQAKLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQISLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGASTAPVPSDNH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: PA2_APIDO
Sequence: IIYPGTLWCGHGNVSSSPDELGRFKHTDSCCRSHDMCPDVMSAGESKHGLTNTASHTRLSCDCDDKFYDCLKNSSDTISSYFVGEMYFNILDTKCYKLEHPVTGCGKRTEGRCLNYTVDKSKPKVYQWFDLRKY
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2, PLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AZOR_SHEB9
Sequence: MSKVLILKSSILGGYSQSAVLIDHLASHWETQGAAITVRDLGGKDVLPMVDGEIASGLRGGAELSARQQEMLALSDTLVAELKANDTIVIAAPMYNFTIPAQLKNWIDFIARAGVTFTYTETGPKGLVEGKRAVLVTTRGGAHKDGPTDHVVPYLKTVLGFIGITNVEVVYAEALNMGPEAHDKGMSEAKHSIDQLKA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: FCTA_ECOL6
Sequence: MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPSVGDVTRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAIDHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPPLVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIPCAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQELGYSDDEIAAMKQNHAI
What is the function of this protein?
Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR).  Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (By similarity).
What are the official names of this protein?
Formyl-CoA:oxalate CoA-transferase, FCOCT, Formyl-coenzyme A transferase, Formyl-CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. Frc subfamily.
Protein: KDGD_METRJ
Sequence: MASMTPAEMARVLGSGLLSFPVTHFRDDLSFDETAYRDNLGRLADYKVSGLFAAGGTGEFFSLTPAEIDRVLRAAVEETRGRTPVIAPAGQGTALAVEMARAAEAAGADGILLLPPYLVGSEQAGLAAHIEAVCRATALGIIVYNRANAQLDERTLAGLCERCPNLVGFKDGVGDVELMTRVYAALGDRLTYIGGLPTAETFALPYLEMGVTTYSSAIFNFLPEWALSFYDSVRRRDRDAVYRELRDFVLPYIAIRNRKRGYAVSIVKAGMSAVGRHAGPVRPPLTELDAAERAELTALIGDRR
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: TSAE_RICCN
Sequence: MHTLNSEEETKKLAKLLAQSLKPNDIVLLNGDLGAGKTFFCREIIKYFCGENTSIISPTFNLLQTYKASNFTIYHYDLYRLKSPEEIYELGFEEALNGNLILIEWSEIIKHLLTPPLIEVNLEALDNNKRLCSIITNHKENSQESSLIDFLQDSPLFDTKLDIQRDKSPTRKVKL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB.  TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE.
What is the protein family that this protein belongs to?
Belongs to the TsaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_ERYLH
Sequence: MRHGISQRKLSRKSGHRKALFRNMSAALIKHEQIVTTLPKAKELRPYVEKLITLAKRGGLSNRRLAMGRLQDETQLKKLFDELADRYSDRDGGYTRIVKAGYRASDSAQLAVIELVDRDEDAKGQDSGPVMVDEDDFAEA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ATPD_PARP8
Sequence: MAELATIARPYAEALFGVAEAGDIAAWSTLVQELAQVARLPDVLSIASSPKVSRAQISDLLLAAVKSPLKDNAQAKNLVQMLVDNHRLPLLPEIATQFEELKNAREGAADALIVSAFPLEGAQLDGLVASLERKFKRKLKPTVQVDSSLIGGVRVTVGDEVLDTSVRARLASMQTALTA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MUC24_BOVIN
Sequence: MSGLSRPLLLAVGCLAALCVITAAGNTTLAPNVTTASSPPPTTTTVPVSPTTLSPLPVTTPAPDICGSRNSCVSCVDGNATCFWIECKGKSYCSDNSTAGDCKVVNTTGFCSVPTTTPTPTNSTAKTTTLPSTTTTSTTATTSGTTNTTLSPTIQPTRKSTFDAASFIGGIVLVLGVQAVIFFLYKFCKSKERNYHTL
What is the function of this protein?
Sialomucin that may play a key role in hematopoiesis.  May be involved in cell adhesion.  Promotes myogenesis by enhancing CXCR4-dependent cell motility.  Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity).
What are the official names of this protein?
Sialomucin core protein 24, MUC-24, Endolyn.
What is the protein family that this protein belongs to?
Belongs to the CD164 family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.
Protein: RL24_AERS4
Sequence: MAAKIRREDEVIVLTGKDKGKRGKVTQVLVTEGKVLVEGINLVKKHQKPVPALGQAGGIISKEAPMDVSNVALFNSAAGKADRVGFRIEDGKKVRFFKSTGELVK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: YCIB_PECCP
Sequence: MKQLLDFIPLVVFFAAYKLYDIYIASGALIAATALSLAVTWMMYRKIEKMTLVTFAMVVVFGSLTLVFHNDLFIKWKVTIIYALFAVALLVSQFVMKQTLIQKMLGKELTLPQSVWGKLNFAWAMFFLVCGLVNIYIAFWLPQSVWVNFKVFGLTGVTLLFTLICGVYIYRHLPGDQEKPEEEKSEQP
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLD_HAES1
Sequence: MNRLLICQNITKHYQEGSLQTQVLKEVSFSMQEGELIAIVGSSGSGKSTLLHMLGGLDQPTSGEVFIHGQSLQRATQDELAKLRNQYLGFVYQFHHLMADFTALENVMMPMLISHKNKTEAKDRAENILSAVGLAKRILHKPSALSGGERQRVAIARSLVNNPKLVLADEPTGNLDHKTTESIFELIQKLNQEQKIAFLLVTHDLQLAEKLGRRLVMQDGILRESNS
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBP26_HUMAN
Sequence: MAALFLRGFVQIGNCKTGISKSKEAFIEAVERKKKDRLVLYFKSGKYSTFRLSDNIQNVVLKSYRGNQNHLHLTLQNNNGLFIEGLSSTDAEQLKIFLDRVHQNEVQPPVRPGKGGSVFSSTTQKEINKTSFHKVDEKSSSKSFEIAKGSGTGVLQRMPLLTSKLTLTCGELSENQHKKRKRMLSSSSEMNEEFLKENNSVEYKKSKADCSRCVSYNREKQLKLKELEENKKLECESSCIMNATGNPYLDDIGLLQALTEKMVLVFLLQQGYSDGYTKWDKLKLFFELFPEKICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLARLLFFKDTYNIEIKEMLLLNLKKAISAAAEIFHGNAQNDAHEFLAHCLDQLKDNMEKLNTIWKPKSEFGEDNFPKQVFADDPDTSGFSCPVITNFELELLHSIACKACGQVILKTELNNYLSINLPQRIKAHPSSIQSTFDLFFGAEELEYKCAKCEHKTSVGVHSFSRLPRILIVHLKRYSLNEFCALKKNDQEVIISKYLKVSSHCNEGTRPPLPLSEDGEITDFQLLKVIRKMTSGNISVSWPATKESKDILAPHIGSDKESEQKKGQTVFKGASRRQQQKYLGKNSKPNELESVYSGDRAFIEKEPLAHLMTYLEDTSLCQFHKAGGKPASSPGTPLSKVDFQTVPENPKRKKYVKTSKFVAFDRIINPTKDLYEDKNIRIPERFQKVSEQTQQCDGMRICEQAPQQALPQSFPKPGTQGHTKNLLRPTKLNLQKSNRNSLLALGSNKNPRNKDILDKIKSKAKETKRNDDKGDHTYRLISVVSHLGKTLKSGHYICDAYDFEKQIWFTYDDMRVLGIQEAQMQEDRRCTGYIFFYMHNEIFEEMLKREENAQLNSKEVEETLQKE
What is the function of this protein?
Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome (By similarity).  Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 26, Deubiquitinating enzyme 26, Ubiquitin thioesterase 26, Ubiquitin-specific-processing protease 26.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH60_WIGBR
Sequence: MAAKDVKFGNDARSKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGSPMITKDGVSVAREVELEDKFENMGAQMLKEVASKANDAAGDGTTTATVLAQSIVNEGLKAVAAGMNPMDLKRGIDKAVIGAVAELKKLSVPCSDSKSIAQVGTISANADKTVGTLIAEAMEKVGKEGVITVEEGSGLQDELDVVEGMQFDRGYLSPYFVNKPEARSVELDNPFILLSDKKISNIREMLPILESVAKAGKPLLIIAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTSGTVISEEMGLDLEKSTLEDMGQAKRVVITKDTTTIIDGTGNKSMISSRVSQINQERDEATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVANRIVNLRGENEDQNVGIRVARRAMEAPLRQIVANAGEEPSVIANKVKAGEGNTGYNAATEVYGNMIDMGILDPTKVTRSALQYAASIAGLMITTECMITDLPKEEKPDLSGAGAGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASATR_DROME
Sequence: MFWHLLCVPNDENASAPDDGNQSCQPSSKQDQYLSPNRNCQKNLLRLYPPPPSKPPPLVGAILQTRLLHQISPSAIADADADLNAVGELLYPNVLQRSATLPAKHNRLGVRSRVTFKVPSSNLPAQDSYSHQPRNQVAVAAKDGILVDVKAKESVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNPSIPIKSDYMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDPLNIKEKVDKNCNATSLAQPAKGSGEPMVQHGNAANNQNITSKGLQQQSTLTNSQVAIANIQSAPSMIEREDVQYTKLEEGAPTKFITMKPNGECDNVDIAAKCIFEQKHVEANDDIVGRASLSGVEQHYKSQIKKHNSPEIANKQIQRTGTVTNDKTSEVNRSTEEQKSTFGRLRVLTAPPMSVHDLPSGGGHSHQVSDLSGKQDPYAATSNAAPIGINSSSTKFGSQHGQIFGLAAMPPINRRSATSTNLRPSSSASQRINSGSTIGGAVGNGSNTARSSVAGDHSVTQFALIDDENVSALQQVTKGGALTLASQWKSQFDDSEDTTDNEWNREHQLQPNLEQLIKLDISLPLNEAKPFPQHGVAGTGKLINPPGEAKGRPKRYTLNITGIENYEALRISIPNCWSEPAMGNVLRKGLEPPAVQQAAFDDTVYRMDIARNVCVRETYSEITHLARPSTSSVLRNRLPSPFKKDSALQLNSTNDSLDKSRHRNSLPNVSVNDIFDDLQMKLNLDLGSAIQENNCCISGRLEIRVIPKDTSHPDDSVYYDAMGAVKNTPTANEGHDHSDQAVNNCDEMEATSAVIAFPNKSISKIMSPPGRDATEERTGASLCSLYSAGVNKLKLNGNTAPRTQFKKGSTDGFGENESEFDFPLLNPSKIPVRQSKCASWAGADFISASKPLESAEVPQEIPYHPQSDTTYSVIDSIPVRKTTYSIALECPPNISDLTPGLSYFYCNIVVPLRLFSILLTES
What is the function of this protein?
Probable serine/threonine protein kinase.
What are the official names of this protein?
Tau-tubulin kinase homolog Asator.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Cytoplasm. Note=Found in the cytoplasm during interphase. Localizes to the mitotic spindle in dividing cells.
Protein: MURI_STRPN
Sequence: MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGPRPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASAAIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSVTKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLLNYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: LEU1_CAMJR
Sequence: MKDNKIIIFDTTLRDGEQALGSSLGINQKLQIALALENLGVDVIEAGFPVSSQGDFKAVQKIASKVKNSTICALSRALDKDIDMAYEALKVAKHFRIHTFIATSTLHMQDKLKKDFDEILSMAKRAIIRARSYTDDVEFSCEDAGRTPIDNLCFMVENAIKAGAKTINIPDTVGYTLPSEFANIIKILFNKVPNIDKAIISVHCHNDLGMATGNSLSAILQGARQIECTINGLGERAGNCALEEVVMAIKTRKDYLKGFYTDIKCENIFKTSKLVSAITNESIPSHKAIVGSNAFSHSSGIHQDGVLKNRQTYEIISPSAIGIHDNRMLMTARSGRAMIKTCLENLGYDENTYNLDDVYERFLRLADKKGQVYDYDLEALMFLSYENEEENEFVIEKLSVISGNIPTACVCMRIKEELKTEACTGNGPVEAVFNCIARITNLKPVLKAYSINAKSSGVDAQGQVDVDLEFKGRKFHGKGLSTDVIEASAQAFASAYNAIYRSLKVEERKMA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: Y415_HELPY
Sequence: MRLLLWWVLVLSLFLNPLRAVEEHETDAVDLFLIFNQINQLNQVIETYKKNPERSAEISLYNTQKNDLIKSLTSKVLNERDKIGIDINQNLKEQEKIKKRLSKSINGDDFYTFMKDRLSLDILLIDEILYRFIDKIRSSIDIFSEQKDVESISDAFLLRLGQFKLYTFPKNLGNVKMHELEQMFSDYELRLNTYTEVLRYIKNHPKEVLPKNLIMEVNMDFVLNKISKVLPFTTHSLQVSKIVLALTILALLLGLRKLITWLLALLLDRIFEIMQRNKKMHVNVQKSIVSPVSVFLALFSCDVALDIFYYPNASPPKVSMWVGAVYIMLLAWLVIALFKGYGEALVTNMATKSTHNFRKEVINLILKVVYFLIFIVALLGVLKQLGFNVSAIIASLGIGGLAVALAVKDVLANFFASVILLLDNSFSQGDWIVCGEVEGTVVEMGLRRTTIRAFDNALLSVPNSELAGKPIRNWSRRKVGRRIKMEIGLTYSSSQSALQLCVKDIKEMLENHPKIANGADSALQNVSDYRYMFKKDIVSIDDFLGYKNNLFVFLDQFADSSINILVYCFSKTVVWEEWLEVKEDVMLKIMGIVEKHHLSFAFPSQSLYVESLPEVSLKEGAKI
What are the official names of this protein?
Uncharacterized MscS family protein HP_0415.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UTP25_PODAN
Sequence: MSLVDSDSDEEEDATSAQPYVNLMKRLIETNPQKAKRRKLDHAPAEDNQPEAAPAPESGDEDERDDEQEEQRDVDEVEEAEEDTADIQPEDLFDEDDDLDETDPFETHISNPDENTVPPRVRAAQNGKWKMQRQPFESTRAYWSYPQTEDGQELPLPAPITSVSNLHLKKRLKEVMEFKRSTFGVVEKTVAPFLFNYRDMLYCDRTVGSSQDLRNLAALHALNHLYKTRDRVIKNNARLAKADANEDLELRDQGFTRPKVLMLLPTRQSCVKMVDSILSVCQPDQQENRKRFEDGYIEKLSKFSDDKPEDFRDLFSGNDDDMFRLGMKFTRKSVKYFSQFYNSDIIFASPLGLRMAIGSEEERKVDFDFLSSIELVIVDQADALLMQNWEHVEFIFEHLNIQPKDAHGCDFSRVRSWYLDDQAKYFRQTVVFSAFNTPELAELMRAHCHNWAGKVRLQQECPGTIQYLPVKARQTFSRFDAPTVAADPDARFNYFTKAIVPLLTKRNAKDANSTLIFIPSYLDFVRVRNFFANNPIVEAVTFGTISEYADIPEASRARSHFLTGRHKVLLYTERAHHFRRYQIKGVKRVIMYSLPDNPLFYREIAGGYLQKSEQSLMVEHGQGVVRVMFSKYDLMKLERIVGTSRVGKMIKEQGDTFDFV
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NUOB_WOLTR
Sequence: MIGQVLSNDDWNRYKKEGFLVTKFGSLIDYVINWARSGSLWPMTFGLACCAVEMMHTASSRYDLDRYGIMFRASPRQADVMIVAGTLTNKMAAALRKVYDQMADPKYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGMLCLQNKIKRTQNI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GPDA_SALPK
Sequence: MNQSNASMTVIGAGSYGTALAITLARNGHQVVLWGHDPKHIATLEHDRCNVAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFSDVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTDETFADDLQQLLHCGKSFRVYINADFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVKGAQDKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKEELSRH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_SHESM
Sequence: MAELTTIARPYAKAAFDVAVEHNAVDTWAEMLTFAALVSENETMQPLLTGSLASTKLAALFISVCGEQINEQGQNLIKVMAENGRLKVLPAVSELFAQYRNEWAKEVEADVVSAAELSSEQKQQISISLEKRLARKVKLNCSTDAALIAGVIIKAGDLVIDGSVRGKLSRLSEKLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y0825_DICDI
Sequence: MDSINMTEKEKMTKGLMYDSFDEELCKDRTEARELIHRFNNSMDKLERKDITKQLFGSTGEKIYIEPTLRVDYGYNIHVGENFFANFGTIFLDTCPITIGKNAMLAPNVQFYSATHPIDPTERNSGLELGRPITIGDNVWIGGGVIILPGVELGDNVVVGAGAVVTKSFGSNVVIAGNPAKIIKQIPVKSE
What are the official names of this protein?
Putative acetyltransferase DDB_G0280825.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: SECB_BARHE
Sequence: MAESEINNNDGEPVFAVLTQYLKDLSFENPSAPRSLRPREKAPQIDININVNANPIGDDNYDVVLSLSVKASDDSETLFHVELIYGGVFHIKNIPQEHVMPLVFIECPRLLFPFARQIISDATQNGGFPPLWIDPIDFAALFQKRVAEEQKNSQTLSS
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y754_ACTP7
Sequence: MTMSTNLCAIYKSPKREGMFLYVAKRDQFDSVPEALRQMFGKPQFVMLFNLNGEKQLKRSKNEEVLQAIQTQGFFLQMPPPPENLLKTFLEQNRGEA
What are the official names of this protein?
YcgL domain-containing protein APP7_0754.
Protein: ASPA_SERMA
Sequence: MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNSKISDVPEFVRGMVMVKKAAAMANKELKTIPRKIADVIIQACDEVLDKGKCMDQFPVDVFQGGAGTSLNMNTNEVLANIGLELMGHQKGEYQYLNPNDHLNKCQSTNDAYPTGFRIAVYASNQKLIDAINQLREGFDRKAKEFETILKMGRTQLQDAVPMTLGQEFHAFSVLLNEETRNLHRTATLLLEVNLGATAIGTALNTPEGYQPLAVQKLAEVSGLPVVPAEDLIEATSDCGAYVMVHSALKRLAVKLSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTCVTMAAEAGQLQLNVMEPVIGQAMFESIHILTNACYNLLEKCINGITANKEVCEHYVFNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSVENLMHPAYKAKRYTDENEQ
What are the official names of this protein?
Aspartate ammonia-lyase, Aspartase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.
Protein: PYRH_SYNS3
Sequence: MAYARALLKLSGEALMGNQGYGIDPEIVQAIARDVAEVVATGTQLAIVVGGGNIFRGLKGSAAGMDRATADYVGMLATVMNAITLQDGLERAGIPTRVQTAIEMQEVAEPYIRRRAMRHLEKGRVVVFGAGCGNPFFTTDTTAALRAAEISADVVFKATKVDGVYDKDPHQFPDAVRYDSLTFQQVLSGELAVMDSTAIALCKDNNIPIVVFNLFEPGNIGKAVAGEPIGSRISN
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.