PharMolix/UniProtQA huggingface dataset:
Protein: LSPA_STRA3
Sequence: MRKIIIPIITILLIALDQLSKLWIVKHIELNQIKEFIPNIVSLTYLRNYGAAFSILQNQQWLFTLITIFVVCVAIIYLMKHINGSYWLLISLTLIISGGLGNFIDRLRLGYVVDMVHLDFINFAIFNVADSYLTIGIICLMIALWKEESNGNHN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RR4_HYMLI
Sequence: RFKKIRRLGALPGFTSKRPRSGSDLKNPLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLRYVQIARKAKGSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKDKQRSKALIQNSIASAPREELPNHLTIDSFQYKGLVNQIIDSKWIGLKIN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PROA_CLOK1
Sequence: MDIYDCILEKAKNANRAARTLSNMSTDIKNAALIKMAEELNKNKDDILKANMLDLEDAKSSGKNDAFIDRLTLNENRIESMASGLMKVASLPDPIGEVTRMWKKSNELNIGRVRVPLGTIGIIYEARPNVTVDAAALCVKSGNSVILKGGKEAINSNLAIYNAINKGAIEAGLPAGTIEFINMTERKAVEVLMKLNEYVDVLIPRGGSGLIKSVVENSTVPVIETGIGNCHVYVDSSADLTMAENIVINAKTQRPGVCNAMETLLVHEAVAEKLIPHLTETLSKMGVEIRGCLKTKRLIPDIRLATAEDYAQEFLDLILAVKVVSSLDEALDHIYKYGTKHSEAIITNDYTSSQRFLREVDAAAVYVNASTRFTDGEEFGFGAEIGISTQKLHARGPMGLNELTTIKYIVYGEGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFNC_METJA
Sequence: MLSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGKTHYTDSRGILELREKISELYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQNPCYPCYKNFIRFLGAKPVFCDFTVESLEEALSDKTKAIIINSPSNPLGEVIDREIYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKTILINGFSKLYAMTGWRIGYVISNDEIIEAILKLQQNLFISAPTISQYAALKAFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEVNNPIGAYYVFPNIGEDGREFAYKLLKEKFVALTPGIGFGSKGKNYIRISYANSYENIKEGLERIKEFLNK
What is the function of this protein?
Catalyzes the transamination reaction between 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) and alanine to produce pyruvate and 5-(aminomethyl)-3-furanmethanol phosphate (F1-P), the precursor for the furan moiety in methanofuran.
What are the official names of this protein?
(5-formylfuran-3-yl)methyl phosphate transaminase, 4-HFC-P:alanine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_NEIMF
Sequence: MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVADENITVATVPGALEIPIALMNLASSEKFDALIAIGVVIRGETYHFELVSNESGAGVSRVALDYNIPIANAVLTTENDAQAIERIEEKASDAAKVAVECANLVNLLLEEQFEDEE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: AMPA_ACIET
Sequence: MNFELKTLSLAAAAAYKCDLLVVLVPEGFLPGSDVLSTLTAHALKQGDLEVKPGKLLQCYAPAGVAARRVVLLGCGAADAHAVRQAMQALAPSFKLPSVKRVALVFGTSAQRGAIGAAVRAVSDGSYVYTATKTKAEPRALLRVTLGVPDAGAAQPEFATATAVAAGVEFAREWANRPANHATPTLVANAAKTLAKYPGVQCQVLGPTEVAKLGMGAFLAVAQGSDQPLRLVELRYNGAARTQAPVVLVGKGITFDTGGISLKPAAEMDEMKFDMGGAASVLGVFRALAELRPAINVVGLIPACENMPDGKAVKPGDVVTSMSGQTIEILNTDAEGRLVLCDALTYAARFKPAAVVDIATLTGACVVALGGLRSGLFASDDLLAEQLLSAGDAALDPCWRMPLDDEYAEGLKSNFADMANVAGRAGGSITAAKFLQRFVGDTPWAHLDIAGTAWKGGAAKGATGRPVGLLVHYLLERATVSTVKPKQKTRSRKSVA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPP_SALTY
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILDRVETIRKLSKSSRAGNEANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPDLNDATIKKAVESLSLELVLTAHPTEITRRTLIHKMGEINNCLKQLDNTDIADYERHQVMRRLRQLIAQSWHTDEIRKQRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVDFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIHVLVSELSMVDATPELLALVGEEGASEPYRYLMKKLRARLMATQSWLEARLKGEKLPKPAGLLTQNEQLWEPLYACYQSLQACGMGIIANGELLDTLRRVKCFGVPLVRIDIRQESTRHTEALGEITRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWEPSNDTREVLETCKVIAEAPKGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNADDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEVTVSSLSLYTSAILEANLLPPPEPKDSWRHIMDELSVISCETYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFSKADLWLADYYDQRLVAKTLWPLGKELRDLLEEDIKVVLAIANDSHLMADLPWIAESIQLRNVYTDPLNVLQAELLYRSRLTEEQGKSPDPRVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: Y3556_DROME
Sequence: MLSLSSPPWLLLLVLFFFANGSATVVSLAENVTLATLPSTSPISVSFSTTSSVVAPISTELENQTASSSNLNTNNEASDEQTGNSNSNTSSHSRNINGLPSSNSNIDNANSNSSSVSSLSTTTSAISGVDQQESLILATPTALNGSGTPPEHQTIGQAPPTKGEQEAILRALDWLKEKRASDYGWGNDTHVVILAKELSGGRDPNDSVDGHVQVIQELEDTLSVKEMEIEILAMLDRHHTLPKPLDLDKLARYVLALGSLCKDPKHFHGHDLVATLQHHEPAQDIEFALTTLSACSSAAHVRKRQIRRLLDIASGVTDQSVDAIAMVILALRCIVTDHRHRHLQHFVRRPARGLATLQDQRGSFGSLRSTALAMQALQDLEYDPAGHWNRTAASRYILSRQRADGGWSEEPLQDGQEPDIGVGLTADIILALGWKGLGAVRALQCDHVIRESSDPTENGEPKLAVPFGLSSSAEESDAKNISYTYTLWVGSNVTESFSLSLVSPKNTSFFKAMTQAAEMDPRFIFEAREWPNGHYVHTLYGKKEEPRGYHYWLLYRLPELPDPNNTPGNQLIAPVGVDELMVEDGEHYLYWYKKL
What are the official names of this protein?
Uncharacterized protein CG3556.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRH_LEGPL
Sequence: MMNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGGNLFRGKALSQAGVGRVTGDHMGMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYHRRKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGADIVLKATKVDGVYSADPLKNPDAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTIVGANHDQ
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WEE2_HUMAN
Sequence: MDDKDIDKELRQKLNFSYCEETEIEGQKKVEESREASSQTPEKGEVQDSEAKGTPPWTPLSNVHELDTSSEKDKESPDQILRTPVSHPLKCPETPAQPDSRSKLLPSDSPSTPKTMLSRLVISPTGKLPSRGPKHLKLTPAPLKDEMTSLALVNINPFTPESYKKLFLQSGGKRKIRGDLEEAGPEEGKGGLPAKRCVLRETNMASRYEKEFLEVEKIGVGEFGTVYKCIKRLDGCVYAIKRSMKTFTELSNENSALHEVYAHAVLGHHPHVVRYYSSWAEDDHMIIQNEYCNGGSLQAAISENTKSGNHFEEPKLKDILLQISLGLNYIHNSSMVHLDIKPSNIFICHKMQSESSGVIEEVENEADWFLSANVMYKIGDLGHATSINKPKVEEGDSRFLANEILQEDYRHLPKADIFALGLTIAVAAGAESLPTNGAAWHHIRKGNFPDVPQELSESFSSLLKNMIQPDAEQRPSAAALARNTVLRPSLGKTEELQQQLNLEKFKTATLERELREAQQAQSPQGYTHHGDTGVSGTHTGSRSTKRLVGGKSARSSSFTSGEREPLH
What is the function of this protein?
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1/CDC2 and acts as a key regulator of meiosis during both prophase I and metaphase II (PubMed:29606300).  Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry.  Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
What are the official names of this protein?
Wee1-like protein kinase 2, Wee1-like protein kinase 1B, Wee1B kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NQOR_ACIET
Sequence: MSKVLVLYYSTYGHLETMAQAVAEGARSAGATVDVKRVPETVPQEIARSAHFKLDQSAPVATVTELENYDAIIVGAPTRFGRMPSQMGSFLDQAGGLWARGALNGKVGAAFTSTATQHGGQETTLFSIITNLLHFGMVIVGLPYSFQGQMTLDEVVGGAPYGATTIAGGQGQRQPSATELDGARFQGRLVAETANKLFGG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: TVA11_HUMAN
Sequence: MWGAFLLYVSMKMGGTAGQSLEQPSEVTAVEGAIVQINCTYQTSGFYGLSWYQQHDGGAPTFLSYNALDGLEETGRFSSFLSRSDSYGYLLLQELQMKDSASYFCAVR
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 1-1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: HDA_ECO27
Sequence: MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: AROC_METRJ
Sequence: MSHNTFGHLFRVTTFGESHGVALGCVVDGCPPGLPLEAEEIQAELDRRKPGQSRFTTQRREPDQVKILSGVFADDRTGGRQLTTGTPIALMIENTDQRSKDYSEIRDSYRPGHADYTYDVKYGIRDYRGGGRSSARETAARVAAGAVARKVIPGVTIRAALVQMGPHAIDRSRWDWDAVGNNPFFCPDAERASFYETYLDGLRKDGSSVGAVIEVVAEGVPPGLGAPVYGKLDADLAAAMMSINAVKGVEIGDGFAAATLRGEDNADEMRAGNGGRPRFLANHAGGILGGISNGEPVVVRFAVKPTSSILTPRRSVTRDGAEVDLVTKGRHDPCVGIRAVPVAEAMMACVLADHYLRHRGQTAGGG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: LYVE1_HUMAN
Sequence: MARCFSLVLLLTSIWTTRLLVQGSLRAEELSIQVSCRIMGITLVSKKANQQLNFTEAKEACRLLGLSLAGKDQVETALKASFETCSYGWVGDGFVVISRISPNPKCGKNGVGVLIWKVPVSRQFAAYCYNSSDTWTNSCIPEIITTKDPIFNTQTATQTTEFIVSDSTYSVASPYSTIPAPTTTPPAPASTSIPRRKKLICVTEVFMETSTMSTETEPFVENKAAFKNEAAGFGGVPTALLVLALLFFGAAAGLGFCYVKRYVKAFPFTNKNQQKEMIETKVVKEEKANDSNPNEESKKTDKNPEESKSPSKTTVRCLEAEV
What is the function of this protein?
Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane.  Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS).  May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes (PubMed:10037799).  Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium (PubMed:26823460).
What are the official names of this protein?
Lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE-1, Cell surface retention sequence-binding protein 1, CRSBP-1, Extracellular link domain-containing protein 1, Hyaluronic acid receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans- Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface. Localizes at cell-cell junctions.
Protein: Y319_MYCPN
Sequence: MSHQEQLHKPNRQQFSEKQFIAFAFNYVAGFGFISVVLTMFKLGPFSYLILGLAALGILGVMLSFSRLSIICGSKAYGGSYLIAKKALGVKTITARFFTFLSGWNVSLTGPFNGLIVPAVLVLSFADIKAVKDNNGALIGLLVGGFVLFGALNFISLFGLKMNKNAILFFAIVKWVVVLGGLILGIYLIGTNHGHGFVENNTLGEHIEDLSFLKVISTTVGMLVAFAGTEDLTAITPDVKSKNIRKCFLLMFGAVTLLYLIGFVIISGISGLNGYGLDGKEKNEKAINTFGSIYFQAGGKYLGIPLLVIFGLGFLLNSLASRLGMTITTARKYVALAQDGFLPSFINEQNKHHEYHKAVWASNIMTLAVMVLMIIVPFLPNDENPGKQLVMFDAISVLVEVAIELAVLISLIQYFITYIFFFMILAKKEGSASVSWWEIASYGVSFAIITVLLFVNLFPITAWKNTNTFKLSILAAFFALGIGFFIHSEIKHKGQLVKSVECN
What are the official names of this protein?
Uncharacterized protein MG226 homolog.
What is the protein family that this protein belongs to?
To M.genitalium MG225.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ECTC_VIBA3
Sequence: MIVRTLDECRNSERRIVSDNWESTRMLLKDDNMGFSFHITTIYEATETHIHYQNHLESVYCMSGEGEIEVVGGETYPIKPGTLYILDKHDEHYLRAYKYKEMVMACVFNPPITGAEVHDENGVYPLVD
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: HMX_STRPU
Sequence: MDSSRELSGEEPRSPSPRHETSKMRLSPDRPSHHPARPPASLASQPLRPAHYQDDDDSYRTHTPPPSQPRTKGFSIESILSPTDKHRKSPRSPPMSPSSPSMSSNGYSEGPIYGSTRHPLSATVPGLGRAALDELAAHRAAALHIPSAALPFSHLAHNPAFYAWMHGASFLHYHGMPAFNSHPPIAQPLTNSSRLAMAKDISPRPTQSHSSFGEEGGEKDSRGRESPDSEHRRNNGHEEDDDDDDDQSPQKKKKKTRTVFSRSQVFQLESTFEVKRYLSSSERAGLAANLHLTETQVKIWFQNRRNKWKRQMAAELESANLAHAAQIRAQANLAQVSAVHVHAYAQRMVRVPILYHENHPTTGSSLHSPNILPFPMPYPGSYHQISSSTSSTSSARSPTSTSIVT
What is the function of this protein?
May be a cell-type-specific regulator of pigment cell differentiation.
What are the official names of this protein?
Homeobox protein Hmx, SpHmx, H6-like.
What is the protein family that this protein belongs to?
Belongs to the HMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AXE1_TALPU
Sequence: MKSLSFSFLVTLFLYLTLSSARTLGKDVNKRVTAGSLQQVTGFGDNASGTLMYIYVPKNLATNPGIVVAIHYCTGTAQAYYTGSPYAQLAEQYGFIVIYPQSPYSGTCWDVSSQAALTHNGGGDSNSIANMVTWTISQYNANTAKVFVTGSSSGAMMTNVMAATYPELFAAATVYSGVGAGCFYSSSNQADAWNSSCATGSVISTPAVWGGIAKNMYSGYSGSRPRMQIYHGSADTTLYPQNYYETCKQWAGVFGYNYDSPQSTLANTPDANYQTTNWGPNLQGIYATGVGHTVPIHGAKDMEWFGFSGSGSSSTTTASATKTSTTSTTSTKTTSSTSSTTTSSTGVAAHWGQCGGSGWTGPTVCESGYTCTYSNAWYSQCL
What is the function of this protein?
Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone.
What are the official names of this protein?
Acetylxylan esterase A, AXE I, Acetylxylan esterase 1.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 1 (CE1) family. AxeA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: STCG_EMENI
Sequence: MEPLDLTCDLTSLNGKSAFITGGASGLGLATARKWAEAGVYITIADIQPPTSPVQPGLAHCFHYVYCDVTSWESQVAAFKSALRFSPSGALDIVACFAGTALAPGNQIDHVLAAGVPSLEVDPPRPSSSVRNIEVNLVGSYFTSWLGLYYLRIPGTGTDPELPSNKCLLFCASIAAYMDSPKASTYPASKFGVRGLFRSTRSQTKQLGVRCNLLAPWFFDSPLIAPIKHAMAARGVDMAKVLTFTSIDACVDAATYCVASPEIHGRALAVQPEGTFDLKDDLEDGWGGNQLRPIMQRRRDAGFDV
What is the function of this protein?
5'-hydroxyaverantin dehydrogenase; part of the gene cluster that mediates the biosynthesis of sterigmatocystin (ST), a polyketide-derived furanocoumarin which is part of the most toxic and carcinogenic compounds among the known mycotoxins (PubMed:8643646).  The first step in the biosynthesis of sterigmatocystin is the production of hexanoate by the fatty acid synthase (FAS) units stcJ and stcK (PubMed:8962148).  The polyketide backbone is assembled by the non-reducing polyketide synthase stcA by condensation of the starter hexanoyl-CoA and 7 malonyl-CoA extender units followed by cyclization and release of norsolorinic acid (By similarity).  Norsolorinic acid is the first stable intermediate in the biosynthesis of sterigmatocystin and is converted into averantin (AVN) by the ketoreductase stcE which reduces the hexanoate ketone to an alcohol (PubMed:8643646) (Probable).  Averantin is then oxidized into 5'-hydroxyaverantin (HAVN) by the cytochrome P450 monooxygenase stcF (PubMed:10618248).  5'-hydroxyaverantin is further converted to 5'-oxyaverantin (OAVN) by the 5'-hydroxyaverantin dehydrogenase stcG (PubMed:24957370).  The next step is the conversion of OAVN into averufin (AVF) which is catalyzed by a yet to be identified enzyme (PubMed:24957370).  The cytochrome P450 monoxygenase stcB and the flavin-binding monooxygenase stcW are both required for the conversion of averufin to 1-hydroxyversicolorone (PubMed:10618248).  The esterase stcI probably catalyzes the formation of versiconal hemiacetal acetate from 1-hydroxyversicolorone (PubMed:24957370).  The oxydoreductase stcN then probably catalyzes the biosynthetic step from versiconal to versicolorin B (VERB) (PubMed:24957370).  The next step is performed by the versicolorin B desaturase stcL to produce versicolorin A (VERA) (PubMed:8999832).  The ketoreductase stcU and the cytochrome P450 monooxygenase stcS are involved in the conversion of versicolorin A to demethylsterigmatocystin (PubMed:7486998).  The Baeyer-Villiger oxidas stcQ and the reductase stcR might be involved in the biosynthetic step from versicolorin A to demethylsterigmatocystin (PubMed:24957370).  The final step in the biosynthesis of sterigmatocystin is the methylation of demethylsterigmatocystin catalyzed by the methyltransferase stcP (PubMed:8900026).
What are the official names of this protein?
5'-hydroxyaverantin dehydrogenase stcG, HAVN dehydrogenase, Sterigmatocystin biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RL2_SHEDO
Sequence: MAVIKCKPTSPGRRHVVKVVNTDLHKGKPFAALLAKKSKSGGRNNTGRITVRHVGGGHKQHYRLIDFKRNKDGIPAKVERIEYDPNRTAHIALVLYADGERRYILAAKGMKSGDPIQSGVGSEIKTGNSMPLRNIPVGSVVHAVEMKPGKGAQIARSAGAYVQVIARDGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGVPTKGYKTRSNKRTDKYIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NAAA_BRASZ
Sequence: MAGSNDVAKVMKTLDGMREGLIQTAVELGSIEAPTGREGAAGDYVYEWMARNGFGPERVGVFDDRFNVVGRLRGTGGGASLSFNSHLDTIMAREDTARFADANDRIYHEAWHEEGRIYGYSVVNCKGPMACWLIAAKALKEAGAALKGDVVLTAVCGEIDCEPVDEFQGHDYLAEDIGARYAISHGAISDYALVAEATNFKPAWVEAGKVFLKVTVFAGPSRYTPYVPRPVAALDSPNAIVRMAKLVEALEEWADNYEKRYTREYGGGTVVPKVAIGAIRGGVPYKIYRFPELCSIYMDIRLNPDTNPLVVQREVEAVVSKLGLKAEVKPFLFRRGYEAQGIEPLQNALEVAHREVVGRPTERPGSPECSMWRDTNPYNELGIPSLTYGCGGGAGGGNTYFLVDDMLKAAKVYAMTAMDLCNRTP
What is the function of this protein?
Catalyzes the deamination of 5-nitroanthranilate (5NAA) to 5-nitrosalicylate (5NSA), the first step in biodegradation of 5-nitroanthranilate.
What are the official names of this protein?
5-nitroanthranilic acid aminohydrolase, 5-nitroanthranilic acid degradation protein A, 5NAA deaminase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: RL31B_STRPN
Sequence: MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.