PharMolix/UniProtQA huggingface dataset:
Protein: Y1301_DICDI
Sequence: MVNNKRKEIENQENDNNDDNDGLLTYKKFKEDINYDSIRSKELQTIAKSLGLPIIGKKQEIYKRIEGYFLSKKVKSDLINSTTNQLQQQPQQPQQQRYVLLIKDVDQLEIYFWKAFRNMIIFKNIFSNFKSKQFGYHDLIGINENFLKSYSNSLEIIKDNIKGNINHQIIRSVNDILNIIKTLKKKDNETISFYNTLFSAFSSTTTQSIKSLIFQFDENIDLWIQRMILNENLVALDQFIKFFKINSDVLKKSIEMHINPSFFNVVTYNNLKIYNYLKSINAIPTSHIKQRFSNIDLSDSLSFDCKLKRLIKSYKLLVDPTNFKKIQEIHQQEEEEQKQQKLNSDKDYIEKLNQLILELSEIESIHFTNDQLNSTIKNLLNQTTTTTTTTTTTTTTTTPILITNNNNSGDIKDIIKKYYKSIYLFFKIIKEGNLYNRNLMKPIHYYLYFKKEKSLIQLYEIFCGKNYTHYLIFFKSILMDQNLEKNQILELVSNILDIENGVPFQNIGCIYNFNLRSFNSFCKVVFSINDTELIDHLIKTIKKLQLVYDSKTKFPSISEIISTNFQYINKNEIVDFFFENYRNETTLFDDQNQNWYNGHVNIIDHYEKLMESIEKRLRLNIVYYYDWFTNVNKINEKKYNINILLDQLKRAISKPLLYSFFNDSGYYYNKLLIIFGWSLENGNEFLINNILSNEQFKQPFRFSEIIDSVLPPNKMSNSVKLIFNNISKESIESKLYQVKVKFNFSYVHGYYYDDFIPLTSTISTTTTTTTTNSEEVGQFIIGETKSFDFTISPRILFVCLYYLDRVDDIFYLFDKIPEIFNSGYFSNFTQESYLYNICSSYYLGLFINYFIENLNDNTINHLYTCLCVASRKGFIQIFQDILSSNKNSQYLLKVRTKTNQSSLFQSNLLCDMVVNSINSSNFQLSNLLIDFIDFSPKNEKVLRSKIFKSSNNK
What are the official names of this protein?
UPF0746 protein DDB_G0281301.
What is the protein family that this protein belongs to?
Belongs to the UPF0746 family.
Protein: C19L2_DROME
Sequence: MSYIQFESGREKDKARQELREAREAMLQQAKERAELRGQRERQKELRGEADWMLPALAKKLEKPAKKSKKNVSKHKSRSKSKSSKKSRKHRNSSSSSESSTSSSSSFSEDEKERKRRKKKSKRSRKESASEDEWVEAPPPLAADNVTKKEPPQRDDWMTSESLLLKTFSRERKEPAKPNEKAQQIDAYDPAKSGRELNPYWKSNGTGLPGFQKPQDDDERQAKPHSSSSAQGSSRGWRKPGAKAPSPPRRSRSRSKSATSSDEEEEEAVQQPKSRPSCLTDEQINELAGKAIKAELKGKKELAAELNQQLEAARKERAEFIASGESVRNANTRPAKSKASAEHVLLTKVDQSGNVRPLVQSGDPNESYGGRMGPKRGSKKVDTHVDGQRVRYFADDDRYDIKQMFEREKHATAAEVNLQYADIVSKHKNPNDDLDDIFADKVRKQISASDAEKREMQSAIREHEKLVATLDNCERCFDSAKLDKQLLVSLGDKIYLSLPWYMGLQSGHCILTTLQHVPCCTQLDEDAWEEISNFRKALTRMFAARRQDVVFYEIANKLHRRPHLSVHCIPIPASQGEMAPFYFKKAIEESEQEWCINKQLVSLRQKSLRAAIPKGLPYVWVHFGMDSGFAHVIEDEDRFPANFAQEILGGMLELNPNAWRKPRKEANPIGKVKSFAENWKKFDCTQN
What are the official names of this protein?
CWF19-like protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the CWF19 family.
Protein: HEM1_TRIV2
Sequence: MNIAVVGLSHKTAPVEIREKLSIPEPQTESAIAQLTSYPHIDEVAILSTCNRLEIYIVAGETDHGIREVTQFLSEHSKLPVHSLRQHLFVLLHEDAVMHIMRVAAGLDSLVLGEGQILAQVKNTHKLGQQYNGIKTILNRLFKQALTAGKRVRTETSIGTGAVSISSAAVELAQIKAENLAACRVTILGAGKMSRLLVQHLVSKGATQISIVNRSRERAQELAKQFSEHPIRTHLLPEMMTVIAESHLVFTSTSATEPILDRAKLEMVLAPNQPLMLFDISVPRNVHTDVNELANVQAFNVDDLKAVVAQNYESRRKMAQEAERLLEEEIEAFDIWWRSLETVSTISSLRSKIETIREQELEKALSRLGSEFGDKHQEVIEALTRGIVNKILHDPMVQLRAQQDVEARRRCMQTLQMLFNLDVGEQFS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: DPO3B_BACSU
Sequence: MKFTIQKDRLVESVQDVLKAVSSRTTIPILTGIKIVASDDGVSFTGSDSDISIESFIPKEEGDKEIVTIEQPGSIVLQARFFSEIVKKLPMATVEIEVQNQYLTIIRSGKAEFNLNGLDADEYPHLPQIEEHHAIQIPTDLLKNLIRQTVFAVSTSETRPILTGVNWKVEQSELLCTATDSHRLALRKAKLDIPEDRSYNVVIPGKSLTELSKILDDNQELVDIVITETQVLFKAKNVLFFSRLLDGNYPDTTSLIPQDSKTEIIVNTKEFLQAIDRASLLAREGRNNVVKLSAKPAESIEISSNSPEIGKVVEAIVADQIEGEELNISFSPKYMLDALKVLEGAEIRVSFTGAMRPFLIRTPNDETIVQLILPVRTY
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_MYCBT
Sequence: MARAVGIDLGTTNSVVSVLEGGDPVVVANSEGSRTTPSIVAFARNGEVLVGQPAKNQAVTNVDRTVRSVKRHMGSDWSIEIDGKKYTAPEISARILMKLKRDAEAYLGEDITDAVITTPAYFNDAQRQATKDAGQIAGLNVLRIVNEPTAAALAYGLDKGEKEQRILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDQRVVDWLVDKFKGTSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRAEFQRITQDLLDRTRKPFQSVIADTGISVSEIDHVVLVGGSTRMPAVTDLVKELTGGKEPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTRLIERNTTIPTKRSETFTTADDNQPSVQIQVYQGEREIAAHNKLLGSFELTGIPPAPRGIPQIEVTFDIDANGIVHVTAKDKGTGKENTIRIQEGSGLSKEDIDRMIKDAEAHAEEDRKRREEADVRNQAETLVYQTEKFVKEQREAEGGSKVPEDTLNKVDAAVAEAKAALGGSDISAIKSAMEKLGQESQALGQAIYEAAQAASQATGAAHPGGEPGGAHPGSADDVVDAEVVDDGREAK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PSD_CHLFF
Sequence: MKKLQYIDRLTNQRVTEAVCYEKTMTLLYTSRLGKWLSTLLAKTPILSRIYGWIQKRSWTRRKIPGFVKRNHICVQEFKKSLSEFSSFNDFFTRELRPEARPIAQGDNICVAPVDGAYLIYPNIAEFGEFVVKSKHFSLSKLLGDASLVEKYASGSVVFARLALFDYHRFHFPVDCWAGPTRNVNGYLFSVHPMALKDNFNIFCENKRTLTELKTEAFGDVLYLEVGALNVGSIIQTYAPEKRYSKGDEKGFFEIGGSTVIILFQPGTIKFDADLLRNSRMGLETRCLMGQSLGRSLGE
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNBI_TUHV2
Sequence: MEDDLNTLAPLGPAAWLFVCPRQDEWCDVLAALSLCDRSSSVAIAPLLVDLTVDRDFQVAVRTPISRYEGGVLTKVTSMWPAAFVFHNAEAIVSRTEDHGDVGGLCAEARARFGVASYRAEAERADTDFTELWAALGVDGARVVMYAVVGYGLKELLYAGQLVPCVEEARTVLLGAVEAFKLPLYPATLFADGDATADGAAAVGLRSRTPFVDRRGLYVSALSEALFYYVFTALGQALRFGHTEHLIDEGMKQFLQDTQNSVKLAPQKRYYGYLSQKLTPGERDQLLLCDAIACELAFSFASVYFDSAYEPAPLMNYSEWPLVRAAEGHADLLRRLSELKLHLSAHVGALVFSGNSVLYQTRIAFFSAANKVPAGGTAQDGLLKAVQFCNGLTCLTEDALNDACRTVKFEGPGGGGGGRDEQFTPQHLAWACATSPHLMSDLVWYLNRLAIYNTGQNGGSALYEHLVHCAVNLCPACRGRCCQSCYQTAFVRIQTRLPPLPKQLKREPFVLTLFSRFLCDVDVLGTFGKRYAGDAKEPSAASLAAAPGEARKVGDEAGLGAGGGGPGGRLGVNVDRLKYFNQILDYCKRNSLIDPSTGEDTLAVRGRADFMSALSGLNRCVDEAAMALVSEVRMKSNRDEVAGATQAFNLDLNPYAVAFSPLLAHQYYRAFFLIVQNLALVSASSYVVDNPLTVSSLSRWLLQHFQSICGAFASNSARKGLLFTKDAKCSKSVEFERFMDFALYAASGRHVLLSTETKLCKLSVCMLRTCRVKNRPIPRGGKGLPVSVFFKRDVVQRRNPVRGCLAFLLYAFHERLFPGCGLSCLDFWQKVYHNALPKSVAIGKMEEFNAFVKYVLNVTTEYNEHDLIDVPPSNLLSYVEYRFHNKFLCFYGFGDYLSTLHGLSTKLVPQNHLNFPHLLAASPKFASVAEYVLYFKKLKLDGVPPPHVATFSRESLVRSVFENRSLVTVAFGIEKYSTSGGSREVFHFGQIGYFAGNGVERSLNVNSMGGGDYRYMRQRFVLATRLVDLLLRRSRRETVLFDADLLRTRVLAALESHDTQLDPELAAIAEIMDGRGGEPPEYEDVLFFVDGQECLAASIVGKIKELIKKGVEDFSLTALGADAGAGGGPAGSAGGPESGGGAGAAGGEGTYDLSALFLDVENECVVLEGPTAAALDGGGDGDECAFPAKRLRL
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework- associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Protein: Y1207_BARQU
Sequence: MNTVTDQPHSISVNQLRAFIERIERLEEEKKTISDDIKEVYAELKGSGFDSKAVRSIIRLRKKEDHERMEEEAIIQLYKNALGMS
What are the official names of this protein?
UPF0335 protein BQ12070.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: PB1F2_I77AB
Sequence: MGQEQGTPWIQSTGHISTQKGEDGQKTPKLEHRNSTRLMGHYQKTMNQVVMPKQIVY
What is the function of this protein?
May play an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm, host cytosol.
Protein: RNH2_CERSK
Sequence: MEITCPDWTHETAALAEGFTCVVGVDEVGRGPLAGPVTAAAVRLFPGRIPEGLNDSKKLTAPRREMLAAEIHTVAEVSIAHASVEEIDRLNILQASHLAMGRALAGLPSRPDFALIDGHMVPKGLGHRCRAIVKGDALCLSIAAASIVAKVARDRIMVDLEQQHPGYGWRTNAGYGTKDHLQALLNLGPTPHHRRSFKPVHNILYQEASISP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAT1_RABIT
Sequence: MGETVPRRRREDEKSIQSDEPKTTSLQKEVGLISGICIIVGTIIGSGIFISPKSVLSNTQAVGPCLIIWAACGVLGTLGALCFAELGTMITKSGGEYPYLMEAFGPIPAYLFSWSSLLVMKPSSFAIICLSFSEYVATPFYSGCEPPKVVVKCLAAAAIMLITTVNSLSVRLGSYVQNFFTAAKLVIVAIIIISGLVLLAQGNTKNFENSFEGAEVSVGAISLALYNGLWAYDGWNQLNYITEELRNPFRNLPLAIIFGIPLVTVCYILINISYFTVMTPTELLQSQAVAVTFGDRVLYPASWIVPVFVAFSTIGAANGTCFTAGRLVYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIVATIYIIPGDINSLVNYFSFATWLFYGLTILGLIVMRFTRKELERPIKVPIFIPILVTFIAAFLVLAPVITNPAWEYLYCVLFILSGLVFYFLFVYYKFEWAQKISKPITMHLQMLMEVVPPEPDPK
What is the function of this protein?
Mediates the electrogenic exchange between cationic amino acids and neutral amino acids, with a stoichiometry of 1:1 (By similarity).  Has system b(0,+)-like activity with high affinity for extracellular cationic amino acids and L-cystine and lower affinity for intracellular neutral amino acids (By similarity).  Substrate exchange is driven by high concentration of intracellular neutral amino acids and the intracellular reduction of L-cystine to L-cysteine (By similarity).  Required for reabsorption of L-cystine and dibasic amino acids across the brush border membrane in renal proximal tubules (By similarity).
What are the official names of this protein?
b(0,+)-type amino acid transporter 1, b(0,+)AT, 4F2-LC6, Glycoprotein-associated amino acid transporter b0,+AT1, Solute carrier family 7 member 9.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: PB2_I68A4
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPMTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEELLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSVAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMIGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLIPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDEGTSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: WASH6_HUMAN
Sequence: MAFHEMQAHKNALGTSGEQQAADITGPTPHQGGWKQVEQSRSQVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPRHRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQVPEIDVPSYLPDLPSIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKADLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDGSSSASPSVQGAPREVVDPSGGWATLLESIRQAGGIGKAKLRSMKERKLEKKKQKEQEQVRATSQGGHLMSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIPPVPPPQQPQAEEDEDDWES
What is the function of this protein?
May act as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
What are the official names of this protein?
WAS protein family homolog 6, Protein FAM39A.
What is the protein family that this protein belongs to?
Belongs to the WASH1 family.
What are the subcellular locations of this protein?
Early endosome membrane. Recycling endosome membrane. Note=Localization to the endosome membrane is mediated via its interaction with WASHC2.
Protein: LIN7A_HUMAN
Sequence: MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
What is the function of this protein?
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.  Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains.  The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).  This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.  Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin.  Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
What are the official names of this protein?
Protein lin-7 homolog A, Lin-7A, hLin-7, Mammalian lin-seven protein 1, MALS-1, Tax interaction protein 33, TIP-33, Vertebrate lin-7 homolog 1, Veli-1.
What is the protein family that this protein belongs to?
Belongs to the lin-7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane protein. Cell junction. Postsynaptic density membrane; Peripheral membrane protein. Cell junction, tight junction. Note=Mainly basolateral in renal epithelial cells.
Protein: YI7I_SCHPO
Sequence: MFYLRVLCVQRRLVREINKLSSFESNWLFLLFLVRVCRQLKTVTVLIVPVLPVYTNKVLRCSQCDWHEPANLDSIYQRSSHDDDLPTIKGSDASTQQYERKTYITDASPESQNLFLSKSKEEGVIFLCIQVSF
What are the official names of this protein?
UPF0768 protein C977.18.
What is the protein family that this protein belongs to?
Belongs to the UPF0768 family.
Protein: ATP61_CHLL3
Sequence: MHLSGDEIIIWQHGFVKLNLTIATTWALMLVLVGGSAFASRRLSNGMHRPRWQNVLEIIVGMARRQIEEVGLRRSMQYLPYLGTLFIFIAFSNLCTIIPGYEPPTGSLSTTAALAMSVFVAVPLFGIAESGLGGYLSTYVKPTPIMLPFNIISELSRTLALAVRLFGNIMSGSMILAILLTVTPFVFPVLMSVLGLLTGMVQAYIFSILATVYISAATRARKE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 1, ATP synthase F0 sector subunit a 1, F-ATPase subunit 6 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BMT3_CANAL
Sequence: MFESDLSFYSALLILCCPISIVFFKKFPIKGYTGANKVSLFLQCLIAILNLNILYSFINSLTITLGHDGSSANTLTIDPITTTQQQGHVDYTPIKVSGYTFKNQVATKNLQCDSIVYDQDLDLQVSQAVDLNKPEDLKFFRDKLNELRSLNNIYDLFFQDNEDEVEESILERKWYKFCGSAVWLDKYGVYFMVNRIAYSKKGTRNNPTISVLAGQVFDKNWIELTGKKFPFSGLEFPTILPHYIDEGKEAEKVILGAEDPRVILHEYTNENGIRIQEPLIAFNALSTEVDWKRAMHIYRPLHDPHRIIRLSIENYAPREKEKNWAPFIDGNNLNFVYNFPLRILRCNINNGDCQKVSGPDFNDKSHENAGKLRGGTNLVEIPSQSLPKHLRSRKYWFGIARSHITDCGCVGELYRPHLILISRNKKSDQYELNYVSDLIDFNVNPEPWTPGKTTCSDGKSVLIPNSVAFIKDDYMSVTFSEADKTNKLINAKGWLTYITKMLEFTQERLKDESSDPVLESRLLSKCSTFLAQQYCALSKDTMGWDKLSR
What is the function of this protein?
Beta-mannosyltransferase involved in cell wall biosynthesis.  Required for addition of the second beta-mannose residue to acid-stable fraction of cell wall phosphopeptidomannan, and in elongation of beta-mannose chains on the phosphopeptidomannan acid-labile fraction.
What are the official names of this protein?
Beta-mannosyltransferase 3, WRY family protein 9.
What is the protein family that this protein belongs to?
Belongs to the BMT family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: DDL_SHEFN
Sequence: MPKINLLLLCGGGGAEHDISLMSARFFESSLAKSDKFSVLKLVLDKHGHYHTEDGKLCDLTNRREIRFEDNSTPAWSVDYVIPCIHGFPGETGDIQSYFNLIQLPYFGCESEASSNCFNKITAKMWFSALGVPNTPYIFLHQLDDDAIKQTETAFDNWGSVFVKAASQGSSVGCYKVDVKANIANVLKDAFSYAPYVVVEQTIHARELEVAVYQYQGEVVATLPGEIICDSNTFYSFDEKYATNSKARTDVVADNLSPEISQLIRDYAVKAFKGMKLRHLSRIDFFLTADNQILLNEINTFPGLTPISMFPKMLQNHGHNFTEYLIDVIGQQVDLT
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYBA_SHIFL
Sequence: MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDSTLCVGCQACVTKCQDINFPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGVNKDQEENGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVPKYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRLALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPKLDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES
What is the function of this protein?
Participates in the periplasmic electron-transferring activity of hydrogenase 2 during its catalytic turnover.
What are the official names of this protein?
Hydrogenase-2 operon protein HybA.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYR_ALKMQ
Sequence: MSDFKQKVSELLGTQIEGIGQRELLEMIEVPPNSEMGDFAFPCFRLAKTFRKAPQVIAEELVAKIQLTDDFEKVDNTGGYLNFFVNRNTYAKAVIQEVLSKGDQYGSRNLGEGKNICIDYSAPNVAKPFHVGHLRSTVIGNSLYRIYDFLGYNCIGINHLGDWGTQFGKVIVAYKNWGDKAEIEKEPINTLLALYVKFHDEAEKNPDLEDEARGWFTKMEKGDEEALSLWKWFSSETIKELKKIYALLDVHFDHYSGESFYNDKMDVVIDELNKQNLLKESQGANIVDLEEYNMPPCLVQKKDGSTLYATRDIAAAIYRKNTFNFEKCLYVTDYSQNLHFAQWFKVIELMGYDWAKDIEHISFGRVTHEGRRIQSRKGSVVLLEEVLNGAVERISEIIEEKNPNVENKEQVAKDVGIGAIVFNDLSNNRIKDISFSWDTAFSFEGETGPYVQYTHARASSVLRKAEVAITDHINAAHLTDDVTMNVIKTIEQFPQVIVDAQRKNEPSIITRHIVNIAQAFNRFYHDHPILVEDEELKMARLAVVQAVKQVLSVGLSLIGIKAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP3B_ORYSJ
Sequence: MAPTVLMVAEKPSIALSIASALSGGRMSTRKGSTDVHEFDGMFQGSHAFFKVTSVIGHVLSVDFPPAYQNWEGTDPMDLFVAPVLRSECNPKAHIRRHLAQEARGCTYLVLWLDCDREGENICYEVIDCTGIPKSEVGRRIFRAKFSSVTEKDIMDAMNNLVLPSKDEALAVDARQEIDLKVGVAFTRFQTRYFQGKYGNLDSRVISYGPCQTPTLGFCVQRYQQITTFKPEKFWSLKTYVIKDGNEIQLEWDRKKLFDFDVTVMFQKMVASDGILKVTDISVKEECKARPPGLNTVNLLKVASSALGIGPQTAMHLAERLYTQGFISYPRTESTAYPSSFDFRSALAALAHNPLWSNDVRTLLDTGFVKPKQGHDAGDHPPITPMRLATEEALGTDAWRLYQYICQHFIGTVSPDCRYTRTSIEFTSGGETFHCVGNRVTSKGFTSIMPWLAVSENNIPAYKKGDAVSIHKVDIYEGSTTPPDYLSESELISLMEKNGIGTDASIPVHVNNICERNYVQVNSGRRLVPTPLGTTLIRGYQCIDADLCLPDIRRFIEQQITLIAKGEADHLQVVQHVLQQFMKKYSYFVKKIENMDALFEAQFSPLADSGRLLSKCGKCARYMKYISTQPMRLYCVTCEEVYYLPQNGSIKLYKEIICPLDGFELLLFSMVGPDAKSFPLCPFCYNSPPFEGIDKLFGALKLDDTGKVGKGAGMPCFLCLHPTCKQSMITQGVCACPECTGTLILDPVSAPKWRLYCNRCNCIVLLPHAAHKISTTDKKCPTCESTIIEVDFNKKTTPLKDGATLHEGCILCDELLHSLIEMKHGKSFFMRRGRGRGRGRGRGRGSSRGRRGSSRHDDPKMSFRDF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).
What are the official names of this protein?
DNA topoisomerase 3-beta.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: TSAD_RICCK
Sequence: MTKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSNLDKALKSVLKESDTKLTEISAIAATSGPGLIGGVIVGSMFARSLSSALKKPFIAINHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAILGLRKYKILGSTIDDAVGEAFDKVAKMLNLGFPGGSEIETRAKFGNSHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMSLKEINDTVVNDIAASFQFTIGEILSSKLQDAIRAYEQMINNCDKKNIVIAGGVAANKYLQEILSSGAKTYGYQLIYPPIHLCTDNAAMIAYAGLERYNNKLFTPLNFCPKARWNLEEI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.