PharMolix/UniProtQA huggingface dataset:
Protein: TXB1B_DANRE
Sequence: MALFLEGTAASSAMETSNFAHVIFQNVGKSYLPHGALECHYTLTQFIKPHPKDWVGIFKVGWSTARDYYTFLWSPLPDNYTEGTAINRSVVFQGYYVPNDDGEFYQFCYVTHKGEIRGASTPFQFRANSPTEEELLTMEDEGGSDILVVTTKASYLEQKMEQIQQEKKELLENLDLLQKERDELIDEKNRLEKEYEQERESSAQLRKDVQELQLSAQSLQEEREEVKRRMEESTARLLQLEEDLIGVTQKGLQKETELDCLKDRVKKLNLEKEALEGQLKNEKDEKELYKIHLKNRELENTKLSAELQMLKSVDVNKENTIAQLKDELARVKSCLAEKEKQHRQLLANSSPSGESKALREQLRQKEEQLQATQQQANMLKAELRDSSNARDRSMAELYRIRVEAETLKKGQADARAECSRLEQQLEEMKSSTQQEAQCKESDVLAVAELQREVEDLRLRLQMAAEHYKDKYKECQKLQKQVVKFNEQQGVKRSPGSDAAAGPLSASPEASAPGSPSTSDAVLDAIIHGRLKSSSKELDKNDKYRKCKQMLNEERERCSMITDELTKMEVKLREQMKTNESLRMQLAAEEDRYKSQVAEKGRELKELKDSLFVLTKEKEKLEGQLQKSVNREEEQKDSNLDVQSVFLQYPMPYAQDDPSPLLVPQRPTDLLFGNPYSSTDSRDGADGEFSDDQMPRLPPVGPPSWDSNVVCIQPARNLSRPDGLEEPEEPQSTQNDDEPAAPEPAEFLNDGQMPFCFEPTGEQKRCPLCEVIFPPHYDQSKFEEHVESHWKICPMCSEQFPLDCDQQLFEKHVLTHFDSNVLNF
What is the function of this protein?
May have anti-apoptotic activity.
What are the official names of this protein?
Tax1-binding protein 1 homolog B.
Protein: GUF1_SORBI
Sequence: MAGAAVLRRSARRIYRHLAAAPAFSRSVLQQPKRLLSSQSSPEHGARGAVSGSELALYPPERVRNFSIIAHVDHGKSTLADRLLELTGTIQKGHGQPQYLDKLQVERERGITVKAQTATMFYRHVSASQDSDTPKYLLNLIDTPGHVDFSYEVSRSLAACQGALLVVDAAQGVQAQTIANFYLAFESNLSIIPVINKIDQPTADPDNVKDQLKRLFDIDPSEALLTSAKTGQGLEQVLPAVIERIPSPPGKCDAPVRMLLLDSYYDEYKGVICHVAIVDGALRKGDKIASAATGRAYEVLDVGIMHPELKPTGVLYTGQVGYVISGMRSTKEARIGDTLHQAKSTVEPLPGFKPAKHMVFSGLYPADGSDFEALSHAIEKLTCNDASVSITKETSNALGMGFRCGFLGLLHMDVFHQRLEQEYGAQVISTIPTVPYIFEYGDGSKVQVENPAALASNPGKRVAACWEPTVIATIIIPSEYVGPVIMLCSERRGEQLEYTFIDAQRALLKYQLPLKEIIVDFYNELKGITSGYATFDYEDSEYQQSDLVKMDILLNGQPVDAMATIVHNQKAQRVGKELVEKLKKFIERQMFEITIQAAIGSKVIARETLSAMRKNVLAKCYGGDITRKKKLLEKQKEGKKRMKRVGSVDIPQEAFHELLKVSNSK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: YMFJ_BACSU
Sequence: MSVLENWDSWKNFLGDRLNYAQDKGMSQDTITDLATEIGSYLANEVESKNEQEKVLADLWSVASKDEQHAIANMMVKLVENNSTH
What are the official names of this protein?
Uncharacterized protein YmfJ.
Protein: LUTB_BACLD
Sequence: MAMKIGTQKFKERVSDGLDNEFMRGAVSSAQERLRARRLEAAKELGNWEEWRSLAEEIRQHVLENLDYYLEQLAENVAKKGGHVFFAQTAEEATGYIRDVVKKKNGKKIVKSKSMVTEEINMNEALESDGCEVVETDLGEYILQIDDHDPPSHIVAPALHKNKEQIRDVFKERIGYRNTEKPEELVMHARAVLRKKFLEADIGITGCNFAIADTGSVSLVTNEGNGRLVTTIPKTQITVMGMERIVPSFDEFEVLVGMLTRSAVGQRLTSYITALTGPRLPGEADGPEEFHLVIVDNGRSNILGTEFQSVLQCIRCAACINVCPVYRHVGGHSYGSIYSGPIGAVLSPLLGGYDDYKELPYASSLCAACSEACPVKIPLHELLLKHRQRIVEKEGRAPISEKLAMKAFGLGTSAPSLYKMGSKWAPAAMKPFKEDGKITKGPGPLKQWTQIRDFPAPNKSRFRDWFEDRRKEKGEDK
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  Has probably a role as an electron transporter during oxidation of L-lactate.
What are the official names of this protein?
Lactate utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the LutB/YkgF family.
Protein: SECA_PSYA2
Sequence: MLSKIIGSVVGTKNERELKRMHKVVSKINAYEATIQALSDEQLQQKTEEFKARHQNGESLDALLPEAFAVCREASLRVNGMRHYDVQLIGGITLHEGKIAEMKTGEGKTLMGTLAMYLNAISGKGVHLVTVNDYLAARDAELNRPLFGFLGMNVGVIYSQQPPQEKVAAYQADITYGTNNEYGFDYLRDNMVFSLREKKQRPLNFCIIDEIDSILIDEARTPLIISGQAEDSSRMYALINTIIPVLIRSKDEEANKNNEEEDFWIDEKNRQIEISEKGYEKIERFLIEVGELGENESLYSPSRLPLLAHVQAAIRAHHVFVKNIHYIVDDGEVVIVDENTGRTMPGRRWSEGLHQAVEAKENVEIQAENQTLATTTFQNFFRLYDKLSGMTGTADTEAAEFKSTYDLDVIVIPTHEPIARIDMDDQIFLTKLGKYKGIIREIQEIQAKGAPVLVGTATIEASEELSYLLDQEGVKHNVLNAKQHEREAEIIAQAGSPKSVTIATNMAGRGTDIILGGNWQSFIEDIDSVSPEEMQRLKAQWQIKHDQVVAAGGLHIIGSERHESRRIDNQLRGRAGRQGDPGMSRFFLSLEDDLMRIFAGDRVVNMMRAMGLKEDEAIEHKMVSKSIENAQGKVESRDFDARKNLLKYDDVANDQRKVIYGQRDDLLAEMDLLQAIKIMHQEVYNAMINQFIPPGSIDDQWNVDGLEDELENEFKIAMPINDWLDEDRRLDEEGLRAKLIQTALDRYDNRREQMGEKEAAQLERHFMLQSLDKHWKEHLTQMDQLRKGIHLRGYAQKNPEQEYKRESFELFQMMLGAIKSETVQDLSRVHIPTKEELAALEVQQRENAAHMQMQFEHSDIDNMDGGVERAAVQGRNVVAGAAGAGVAGAMAGNGNNDNEPNPYAGMNISRNAPCPCGSALKYKQCHGKI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: APAG_SERP5
Sequence: MIDSPRVCIQVQSVYVESQSIPEEERYVFAYTITIRNLGRFNVQLLGRYWLITNSNGRQTEVQGEGVVGEQPLIPPGGEFQYTSGAILETPLGTMEGHYEMVDHQGQPFQTAIPVFRLAIPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: MURE_ECO57
Sequence: MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKGEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQDATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEDRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21A_YEAST
Sequence: MGKSHGYRSRTRYMFQRDFRKHGAVHLSTYLKVYKVGDIVDIKANGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L21-A, Large ribosomal subunit protein eL21-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_SALEP
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDSDFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDKIIKLDLVDAMIQGADPKVSDDQSNQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELDRAGLLNCNVKNVLGLTLPQTLEQYDITVTQDEAVKKMFRAGPAGIRTTQAFSQDCRWDSLDDDRAAGCIRSLEYAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVEGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGTIALIEDGDTIAIDIPNRSIQLQLNEAEIAARREAQEARGDKAWTPKNRQRQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: HFLD_AERS4
Sequence: MSDKFQDRTMAFAGICQAAYLVQKVARDGTCDEASLRESLQSVLVTDPKQPLEVFGNHLAIRDGYRALVEQLGSDGSQKNAELTRYVVSLIALERKLAKRKDILNMLGERISQIGRQQQHFDLLDEQILANMASIYSDLISPIGPRIQIAGTPLFLQQPLVQHKVRALLLAGIRACVLWRQLDGSRTQIIFARKKMVELAKRF
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYA_STRP6
Sequence: MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSGVATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRDEAIEWGFELLTSPEWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEIGAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYDPDGDNMSFKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTVGQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGKDIFKLYDTYGFPVELIEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNETLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVADTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKNHTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIWNALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGLFKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALSDSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWKQKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGSDASKIAELLAAVAETV
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_CYTH3
Sequence: MTEIRNNWTKEEISAIYNSPILDLMYRGATVHREFHDPQEVQVCTLLSIKTGGCPEDCSYCPQAARYHTDVKVEKLMDVKDVLNSALEAKESGSTRFCMGAAWREVRDNKDFDKVIDMVKGVSTMGMEVCCTLGMLTPEQADKLKDAGLYAYNHNLDTSAEHYDKVITTRTYDDRLETLDNVRNAKISVCSGGIIGMGESHGDRVGMLHTLANMVEHPESVPVNALVPVEGTPLEDQPRVSVWEMVRMIATARIIMPKAMVRLSAGRVRMNTEEQALCFLAGANSIFAGDKLLTTPNPEVNADKEMFQVLNLKPRQSFKNGDAPKIKFEQIPSALVK
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: DNLI4_CHICK
Sequence: MASAPVLQPSPKRTVASHVPFADLCSTLERIQTCKSRPEKTKYFKDFLDSWRKFHSALHQKEKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPKDGKDAVKLLNYRTPTGSRGDAGDFAMIAYFVLKPRSPKRGRLTVEQVNELLDAIANNNAAKNKGLVKKSLLQLITQSTALEQKWLIRMIIKDLKLGVSQQTIFSIFHPDAAELHNVTTDLEKVCRQLHDPSVSLSDVSIMLFSAFKPMLAAIADVQQIEKQMNNQVFYIETKLDGERMQMHKDGDVYKYFSRNGFDYTQQFGASPVDGSLTPFIHNVFKSDIQNCILDGEMMAYNPETQTFMQKGNKFDIKRMVEDSDLQTCFCVFDVLMINDQKLAHESLSKRYKILSNVFTPLTGRIHVVHKKSARTRKEVIDALNEAIDNREEGIMVKDPMSTYKPDKRGEGWLKIKPEYVNGLMDELDLLIVGGYWGKGSRGGMMSHFLCAVAETPAPNEKPTVFHSICRVGSGYTMKELYDLGLKLAKHWKPYNRKDPPCNILCGTEKPEMYIEPCNSVIVQIKAAEIVNSDMYKTDCTLRFPRIEKIREDKEWYECMTLDMLEHLRSRAEGKLASKHLYIDEYDEPQEKKRRTVPKVKKVIGIAEQFKAPDLSNVNKVSSMFEDVEFCVMTGMGRYSKSELESRIAECGGSVVQNPGPDTYCVIVGAENVRVKNIIASNKYDVVKAEWLLQCFQSKMLVPWQPAFMIHMSPETREHFAREYDCYGDSYTADTDVAQLKEVFSRVKDNKKMPLDLIAELEERYSWNSCKLCIFRGNTIYVDYYAIINKPSTKIHGTRLSIRALELRFYGAKVVPLLEEGVSHVVIGEDHSRVKEMKALRRMFGKKFKIVSELWVTESVKEGVPKNETQFLI
What is the function of this protein?
DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair and V(D)J recombination.  Catalyzes the NHEJ ligation step of the broken DNA during DSB repair by resealing the DNA breaks after the gap filling is completed.  Joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction.  LIG4 is mechanistically flexible: it can ligate nicks as well as compatible DNA overhangs alone, while in the presence of XRCC4, it can ligate ends with 2-nucleotides (nt) microhomology and 1-nt gaps.  Forms a subcomplex with XRCC4; the LIG4-XRCC4 subcomplex is responsible for the NHEJ ligation step and XRCC4 enhances the joining activity of LIG4.
What are the official names of this protein?
DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPX2_RAT
Sequence: MAYIAKSFYDLSAIGLDGEKIDFNTFRGRAVLIENVASLUGTTTRDYTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRHGGGFQPTFSLTQKCDVNGQNQHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVSWNFEKFLIGPEGEPFRRYSRTFQTINIEPDIKRLLKVAI
What is the function of this protein?
Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides.  Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors.
What are the official names of this protein?
Glutathione peroxidase 2, GPx-2, GSHPx-2, Glutathione peroxidase-gastrointestinal, GPx-GI, GSHPx-GI.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MIAA_ECO5E
Sequence: MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLGGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: COAD_PROM5
Sequence: MKILYPGTFDPLTNGHLDLIQRAEKLFGNVVVAVLENTSKKPTFELSRRLIQINNAISHLSKISVISYEGLTVDCAQDVNANLILRGLRAMSDFEYELQIAHTNKSLNSEIETIFLSTNTNFSFLSSSLVKEVAKFGGEINHMVPEAVERDLKEYFKKN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEZ6_BOVIN
Sequence: MRPAALLLLPSLLALLVHGLSLEAPTEGEGQAPGLEEMDGELTAAPTPEQPEPGVHFVTTAPTLKLLNHHPLLEEFLQEGQEKDELRPDPPTASPLPRLANQDSRPVFTSPTPVMVAAPTQPQSREGPWSLESEPPALRITVALPPGPGMAVPTPGPGERPNTPPPSGAWTPTPEGPGDIGRPWAPGVMSQTTGLGMEGTVATSTASGDDEETTSTSTIITTAVTTVQPPGPCSWNFSGPEGSLDSPTASNSPPDVGLDCFYYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGAVTVTSLHPGGSARFRCATGYQLKGARLLTCLNATQPFWDSQEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSSRHFFVELSTDSSGVAAGMALRYEAFQQGHCYEPFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGETTDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDVRVLRIGTGDVLTFYDGDDLTARVLGQYSGPRGHFKLFTSMADVTIQFQSDPGASVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCLDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLTGSALLTCHDRQASSPKWSDRTPKCLLEQLKPCHGLSAPENGARSPEKRLHPAGATVHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYSGRSLDVAKVPAASSTLDAAHLAAAIFLPLVAMALLVGGVYLYFCRLQGNSPLQLPRTRPRPYDRITVESAFDNPTYETGSLSFAGDERI
What is the function of this protein?
May play a role in cell-cell recognition and in neuronal membrane signaling.  Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor.  Involved in the development of appropriate excitatory synaptic connectivity (By similarity).
What are the official names of this protein?
Seizure protein 6 homolog, SEZ-6.
What is the protein family that this protein belongs to?
Belongs to the SEZ6 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localized on dendrites and in the synaptic and postsynaptic fraction.
Protein: RL33_BRUMB
Sequence: MAKATTIKIKLLSTADTGFFYVTKKNSRTMTEKMTKTKYDPIARKHVEFKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RLMH_STAAM
Sequence: MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAA_METBA
Sequence: MSEFTLKTRLLAALEGKPVDKVPVCSVTQTGIVELMDEVGAAWPEAHTNPELMAKLAIANYELSGLEAVRLPYCLTVLGEAMGCEINMGTKNRQPSVTASPYPKNLDGAAVPADLLQRNRIPAVLEAIKIVREKVGPDVPIIGGMEGPVTLASDLISVKSFMKWSIKKTDLFEQALDISTEAAIAYANAMVEAGADVIAIADPVASPDLMSPDTFRQFLQSRLQKFSASVNSVTVLHICGKVNAILSDMADCGFEGLSVEEKIGDAAEGKKVIGDRARLVGNISSPFTLLPGPIDKIKAEAKVALEGGIDVLAPGCGIAPMTPLENIKALVAARDEYYA
What is the function of this protein?
Methyltransferase involved in methanogenesis in the methanol pathway.  Catalyzes the transfer of the methyl group from the methylated corrinoid protein MtaC to coenzyme M, forming the substrate for coenzyme-B sulfoethylthiotransferase.  MtaC can be substituted by free cob(I)alamin in vitro.
What are the official names of this protein?
Methylcobamide:CoM methyltransferase MtaA, Methylcobalamin: Coenzyme M methyltransferase, Methylcobamide:CoM methyltransferase II isozyme M, MT2-M, [Methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family. MtbA/mtaA subfamily.
Protein: GYRA_STAAW
Sequence: MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGKIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTENGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGDDQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDIQQSSDEE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFDB_METTH
Sequence: MELPQNVQHQLAQFQQLQQQAQAISVQKQTVEMQINETQKALEELSRAADDAEVYKSSGNILIRVAKDELTEELQEKLETLQLREKTIERQEERVMKKLQEMQVNIQEAMKGAGINPGMGN
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HETR_TRIV2
Sequence: MSNDIDLIKRLGPSAMDQIMLYLAFSAMRTSGHRHGAFLDAAATAAKCAIYMTYLEQGQNLRMTGHLHHLEPKRVKIIVEEVRQALMEGKLLKTLGSQEPRYLIQFPYVWMEQYPWIPGRSRIPGTSLTSEEKRQIEHKLPSNLPDAQLVTSFEFLELIEFLHKRSQEDLPPEHRMELSEALAEHIKRRLLYSGTVTRIDSPWGMPFYALTRPFYAPADDQERTYIMVEDTARYFRMMKDWAEKRPNAMRALEELDVPPERWDEAMQELDEIIRTWADKYHQVGGIPMILQMVFGRKED
What is the function of this protein?
Controls heterocyst differentiation.  Dimerization is required for DNA-binding.  Has both a protease and a DNA-binding activity.
What are the official names of this protein?
DNA-binding transcriptional activator HetR, Heterocyst differentiation control protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S48 family.
Protein: GPX5_MOUSE
Sequence: MVTELRVFYLVPLLLASYVQTTPRPEKMKMDCYKDVKGTIYDYEALSLNGKEHIPFKQYAGKHVLFVNVATYCGLTIQYPELNALQEDLKPFGLVILGFPCNQFGKQEPGDNLEILPGLKYVRPGKGFLPNFQLFAKGDVNGENEQKIFTFLKRSCPHPSETVVMSKHTFWEPIKVHDIRWNFEKFLVGPDGIPVMRWFHQAPVSTVKSDIMAYLSHFKTI
What is the function of this protein?
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.  May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
What are the official names of this protein?
Epididymal secretory glutathione peroxidase, Epididymis-specific glutathione peroxidase-like protein, EGLP, Glutathione peroxidase 5, GPx-5, GSHPx-5, Major androgen-regulated protein, arMEP24.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Secreted.