PharMolix/UniProtQA huggingface dataset:
Protein: SUVH2_ARATH
Sequence: MSTLLPFPDLNLMPDSQSSTAGTTAGDTVVTGKLEVKSEPIEEWQTPPSSTSDQSANTDLIAEFIRISELFRSAFKPLQVKGLDGVSVYGLDSGAIVAVPEKENRELIEPPPGFKDNRVSTVVVSPKFERPRELARIAILGHEQRKELRQVMKRTRMTYESLRIHLMAESMKNHVLGQGRRRRSDMAAAYIMRDRGLWLNYDKHIVGPVTGVEVGDIFFYRMELCVLGLHGQTQAGIDCLTAERSATGEPIATSIVVSGGYEDDEDTGDVLVYTGHGGQDHQHKQCDNQRLVGGNLGMERSMHYGIEVRVIRGIKYENSISSKVYVYDGLYKIVDWWFAVGKSGFGVFKFRLVRIEGQPMMGSAVMRFAQTLRNKPSMVRPTGYVSFDLSNKKENVPVFLYNDVDGDQEPRHYEYIAKAVFPPGIFGQGGISRTGCECKLSCTDDCLCARKNGGEFAYDDNGHLLKGKHVVFECGEFCTCGPSCKSRVTQKGLRNRLEVFRSKETGWGVRTLDLIEAGAFICEYAGVVVTRLQAEILSMNGDVMVYPGRFTDQWRNWGDLSQVYPDFVRPNYPSLPPLDFSMDVSRMRNVACYISHSKEPNVMVQFVLHDHNHLMFPRVMLFALENISPLAELSLDYGLADEVNGKLAICN
What is the function of this protein?
Histone methyltransferase family member that plays a central role in gene silencing (PubMed:15775980, PubMed:16384625, PubMed:19043555, PubMed:24463519, PubMed:27171427).  Together with MORC6 and SUVH9, regulates the silencing of some transposable elements (TEs) (PubMed:27171427).  According to PubMed:15775980, it is required for normal methylation of 'Lys-9' and 'Lys-27' of histone H3, 'Lys-20' of H4, and cytosine, but PubMed:19043555 see no significant effect on histone methylation when the gene is mutated.  According to PubMed:19043555, the protein does not bind S-adenosyl-L-methionine and lacks methyltransferase activity.  Instead, it may function downstream of DRM2 in RNA-directed DNA methylation, binding to methylated DNA and recruiting DNA-directed RNA polymerase V to chromatin (PubMed:24463519, PubMed:27171427).
What are the official names of this protein?
Histone-lysine N-methyltransferase family member SUVH2, Cytosine-HMTase 2, H3-K27-HMTase 2, H4-K20-HMTase 2, Histone H3-K9 methyltransferase 2, H3-K9-HMTase 2, Protein SET DOMAIN GROUP 3, Suppressor of variegation 3-9 homolog protein 2, Su(var)3-9 homolog protein 2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associates with centromeric constitutive heterochromatin.
Protein: DCNL2_MOUSE
Sequence: MHKLKSAQKDKVRQFMACTQASERTAIYCLTQNEWKLDEATDSFFQNPEAFHRESMKSSVDQKKLEQLYSRYKDPQDENKIGIDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSKKEFVDGMTELGCDSTERLKALLPRLEQELKDPAKFKDLYQFTFTFAKNPGQKGLDLEMAVAYWKLVLSGRFKFLDLWNTFLLEHHKRSIPRDTWNLLLDFGNMIADDLSNYDEEGAWPVLIDDFVEYARPVVTGGRRSPF
What is the function of this protein?
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and plays an essential role in the regulation of SCF (SKP1-CUL1-F-box protein)-type complexes activity.
What are the official names of this protein?
DCN1-like protein 2, DCNL2, DCUN1 domain-containing protein 2, Defective in cullin neddylation protein 1-like protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DIDA_AGKPI
Sequence: MIQVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKITPLPKGAVQPKNPCCDAATCKLTPGSQCAEGLCCDQCKFIKAGKICRRARGDNPDYRCTGQSGDCPRKHFYA
What is the function of this protein?
Inhibits fibrinogen interaction with platelets.  Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) on the platelet surface and inhibits both ADP-induced platelet aggregation and platelet aggregate dissociation in human platelet-rich plasma.
What are the official names of this protein?
Disintegrin piscivostatin-alpha, PVS-alpha.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACAD8_MOUSE
Sequence: MAMLRSGYRRFGCLRAALKSLAQTHHRSITFCIDPSLGLNEEQKGFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYVRTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKQQGDHYILNGSKAFISGGGESDIYVVMCRTGGSGAKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGTEGQGFLIAMKGLNGGRINVASCSLGAAHASVILTQEHLKVRKQFGAPLARSQYLQFQLADMATKLVASRLMIRTAAVALQEEREDAVALCSMAKLFATEECFAICNQALQMHGGYGYLKDYAVQQYMRDSRVHQILEGSNEVMRMLISRNLLQD
What is the function of this protein?
Isobutyryl-CoA dehydrogenase which catalyzes one of the steps of the valine catabolic pathway.  To a lesser extent, is also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA.
What are the official names of this protein?
Isobutyryl-CoA dehydrogenase, mitochondrial, Acyl-CoA dehydrogenase family member 8, ACAD-8.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SPEFL_HAEIN
Sequence: MLFRTYIHRYVHTKALRFLRFNPIKGRSLMAHIRRTRHIMMPSYRSCFSYSLFASQNKPSNRAL
What is the function of this protein?
A small protein (arrest peptide) encoded upstream of inducible ornithine carboxylase gene (speF) that controls expression of downstream genes (usually speF and potE) by transcriptional and translational attenuation.
What are the official names of this protein?
Leader peptide SpeFL, Arrest peptide SpeFL.
What is the protein family that this protein belongs to?
Belongs to the speF operon leader peptide family.
Protein: COF_YERPG
Sequence: MYRLAAFDMDGTLLMRDHKIGSITLNALHQLADAGVTLTFATGRHYLDMKGILSHSGLNGYLITGNGTRVCDAEGNPLYGMDLPAELVEFVLRTPWQTNASIHLFRDDGWFTDRNDPDLLIAHTTSGFHFQLTEWDELPLTGNHKFCFIASHQELVELKAQLEQQMGGEADFCFSATDCLEVLPRGCNKGVALEKLSHHLDLTLADCMAFGDAMNDKEMLSRVGRGLVMGNALPQLKQELPQLQIIGRCEQQGVAHYLHHWLSSPHLTYSPEF
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: CKX_WHEAT
Sequence: FLPKSLFTLVTDKSL
What is the function of this protein?
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group.  Substrate preference is 2-(2-hydroxyethylamino)-9-methyl-N(6)-isopentenyladenine >> isopentenyladenine > cis-zeatin = isopentenyladenosine = zeatin >> zeatin riboside.
What are the official names of this protein?
Cytokinin dehydrogenase, Cytokinin oxidase, CKO, CKX.
What are the subcellular locations of this protein?
Membrane. Note=Might be located on membranes.
Protein: CHM1B_ARATH
Sequence: MGNTDKLMNQIFDLKFTSKSLQRQSRKCEKEEKAEKLKVKKAIEKGNMDGARIYAENAIRKRSEQMNYLRLASRLDAVVARLDTQAKMTTITKSMTNIVKSLESSLATGNLQKMSETMDSFEKQFVNMEVQAEFMENAMAGSTSLSTPEGEVNSLMQQVADDYGLEVSVGLPQPAGHAIPTKTEEKVDEDDLSRRLAELKARG
What is the function of this protein?
Involved in ESCRT-dependent multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  Mediates the MVB sorting of the auxin carriers PIN1, PIN2 and AUX1.  Required for embryonic axis establishment and seedling growth (PubMed:19304934).  Required for autophagic degradation of plastid proteins.  Promotes the efficient sequestration of cargo from plastids into autophagosomes.  Mediates the efficient delivery of autophagic plastid bodies to the vacuole, but not into the cytoplasm (PubMed:25649438).
What are the official names of this protein?
ESCRT-related protein CHMP1B, Protein CHARGED MULTIVESICULAR BODY PROTEIN 1B, Protein CHROMATIN MODIFYING PROTEIN 1B, Vacuolar protein-sorting-associated protein 46.2.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: PYRD_LEGPC
Sequence: MYSLLRPLLFRLDAEKAHSLTLSLLHYLPGFYFRKIAGQPVHAMGLVFPHQVGLAAGLDKNGEHLDALAKLGFSFIELGTVTPKGQAGNPKPRLFRIAEANAIINRMGFNNSGVDVLVENVKRANYKGILGINIGKNKETNLNQAAEDYLYCFRKVYDHASYVTINISSPNTPDLRQLQQGDYFAELLTQLQKEQIKLADQYGRHVPLVVKVSPDETDETLKQMTDIILQYGIEGIIATNTTCSREMVKNLPCSEEQGGLSGRPLMELSTRCLRLLKQYVGNDVTLIGVGGIDSLESAKDKINAGASLLQVYSGLVYKGPELIHDIVSGLNAI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YN36_YEAST
Sequence: MKASKISDSRLRGIDGTVDSPCRHCIARVVILAFLDWQANTKGSAKSGCLSSSSKLCTLFNISMDLSLAWRMVEFLLFDSEDKERNSASSCLCMESNPPVFMAI
What are the official names of this protein?
Putative uncharacterized protein YNL296W.
Protein: CCL20_BOVIN
Sequence: MMCSSKNLLLAALMSVLLLHFCSKSEASNFDCCLRYTERILHPSILVGFTQQLANEACDINAVVFYTRKKLAVCADPKKKWVKQVVHMLSQRVKRM
What is the function of this protein?
Acts as a ligand for C-C chemokine receptor CCR6.  Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions.  The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and autoimmune diseases.  CCL20 acts as a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes.  Involved in the recruitment of both the pro-inflammatory IL17 producing helper T-cells (Th17) and the regulatory T-cells (Treg) to sites of inflammation.  Required for optimal migration of thymic natural regulatory T cells (nTregs) and DN1 early thymocyte progenitor cells.  Positively regulates sperm motility and chemotaxis via its binding to CCR6 which triggers Ca2+ mobilization in the sperm which is important for its motility.  May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells.
What are the official names of this protein?
C-C motif chemokine 20, Macrophage inflammatory protein 3 alpha, MIP-3-alpha, Small-inducible cytokine A20.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LFTR_SALTI
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQHGIFPWFSPGDPILWWSPDPRAVLWPEKFHLSRSMKRFHNASPYRVTLNYAFDRVIDGCANHRDEGTWITRGIEEAYRRLHELGHAHSIEVWRDRELVGGMYGVSQGALFCGESMFSRQENASKTALLVFCAEFTRHGGKLIDCQVLNSHTASLGAIEIPRRDYLDHLAALRQQPLASRFWVPRTLFLPRK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAX82_MESMA
Sequence: MSRLYAIILIALVFNVVMTITPDMKVEAATCEDCPEHCATQNARAKCDNDKCVCEPK
What is the function of this protein?
This toxin inhibits rKv1. 1/KCNA1 (100% inhibition at 3 uM), Kv1. 3/KCNA3 (human, mouse and rat) (IC(50)=269-467 nM), shaker IR (60% at 3 uM) and activates the mouse capsaicin receptor TRPV1 (EC(50)=132 uM, at 20 degrees Celsius), a non-selective cation channel expressed by sensory neurons of the pain pathway (PubMed:26389953, PubMed:20889474).  In vivo, intraplantar injection of this toxin in WT mice hind paw shows significant acute pain, whereas no pain is observed when the toxin is injected into TRPV1 KO mice (PubMed:26389953).  In addition, subcutaneous injection into mice (185 mg) produces an excitation of the animal, but no lethality, whereas injection into cockroaches does not provoke lethality as well (PubMed:9151979).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 8.2, Neurotoxin BmP01.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 08 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LUTA1_BACMK
Sequence: MKVSIFITCVADVFYPEVGKDVVEILEDLGCEVDFPKTQTCCGQPAYNSGYVKETKTAAKHMIEAFASSEYVVAPSGSCAMMVHEFSSLFSESEADWKKKATELGNKTYEFTQFLVEVLGKEDLGAELHKKATVHTSCHMSRLMGIKEPPQKLLKCVKGLEVVSLPHNYDCCGFGGTFSVKMPEISEQMVEEKVKHIMETGAELLIGMDCSCLMNIKGRLTRNGYPIDVKHIAQVLNEDRKQGGI
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A 1.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: SIHH_METAC
Sequence: MTEQELVESGNMKMEWARNHMPVIAIIREKFEKEKPLKGLKVGMALHVEAKTAVLVETLAAGGAQVAISGCNPLSTQDDVARALDTRKNISCFARYGCCTSEYYEAIDKVLDIEPDITIDDGADLIFKLHKERTDLLPKILGGCEETTTGVHRLHAMEKEGALKMPVIAVNDAMTKYLFDNRYGTGQSAWDGINRTTNLLVAGKNVVVGGYGWCGRGVAMRAAGLGANVIVTEVDPIRALEARMDGYRVMRMADAARLGEIFVTTTGNRDILTAEHFKVMPDGAVLANSGHFNVEIDMEALTSLAKSVKTVRHNIKEYDIGDRRINVIAEGRLVNLAAGDGHPAEVMDMSFANQALCVRYIAENTLLNGVHGVPRGIDTYVAKLKLESMGISIDELTSKQECYMTGWECGT
What is the function of this protein?
Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  Can also catalyze the reverse reaction in vitro, i. e.  the synthesis of SIH from Hcy and inosine.
What are the official names of this protein?
S-inosyl-L-homocysteine hydrolase, SIHH.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODC_ZANAE
Sequence: MVKAVAVLTGSEGVQGTVFFAQEGEGPTTITGSLSGLKPGLHGFHVHALGDTTNGCMSTGPHFNPAGKEHGAPEDGNRHAGDLGNVTVGEDGTVNFTVTDSQIPLTGLNSVVGRAVVVHADSDDLGKGGHELSKTTGNAGGRLACGVIGLQA
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPFG_KLEOX
Sequence: MKVNHTTACGTQPFDKTYSLGYQVHHEDWSPYPRVNRLRQAFLDRPYDIDVERLRLVTEAYQKHEDAPRKLKCARAFENILLNTKLYIYDEDLILGEIAAPAKASPIYPEFSVNWIINEILHSPFEERANDQFYIRNDEERKEIVELCRYWEGKTVDDLINSRLEIDQTKGSEVGEKIFQTNLYHYAGAGHLAIDYARLMAVGYNGLIDNAQAGLEKLSKRDPEYGDKRDFYTAMIIELEAAKKYIARYAKLAQESAEKEENPQRKQELETMALNCQQIAGGVPQTFWQALQLFNFATTLIQIESNGHSISYGRMDQWLYPWFAADMKNNTITKEFALELIEVQYVKMNNPTKLKDKGTVAVRNGRGFGGESLTLGGVDREGNDATNDLTMLMLEGSAHTRMMNPWVCVRMHENTPYELKIKTVECIRAGYGHPKLFNDAPSIKGMMRKGMTLEEARDYCVVGCVELDLAGKEYGWHDAAYVNTPKMMEMVVNGGRSLSTGEQLGPDTGSLDTYKSFDEVLASVDQQFEYWTDQMCSSLNIIDNAHRELKPVPYVSAFYEDCMISGKDLTEGGAKYNGIAPQAAGMATCADSLATIKQLVFDEKRYSGAEMLQAVKDNWVGHEKLYALVNSSKVRHYGNDDDYADDLFKFMFECYCRHISGRKTPRGGEFSPGVYSVNANVGMGLNTNASIDGRKKFEPISDNMGPVHTDGGSHDICGPTALVNSLTKVDHSLATNGTLMNLRFPQEAVAGVEGRDNLLSFIDEYIAKQAMHVQFNIMSSATMRAAQKKPEDYKDMLVRVAGYSAYFVELGKPLQKDLIQRTELHF
What is the function of this protein?
Involved in the degradation of the organosulfur compound 2(S)-dihydroxypropanesulfonate (DHPS) (PubMed:32571930).  Catalyzes the radical-mediated dehydration of DHPS to produce 3-sulfopropionaldehyde (3-oxopropane-1-sulfonate) (PubMed:32571930).
What are the official names of this protein?
(2S)-3-sulfopropanediol dehydratase, (S)-DHPS dehydratase.
What is the protein family that this protein belongs to?
Belongs to the glycyl radical enzyme (GRE) family.
Protein: KITH_DICTD
Sequence: MEIVSGASGWIEVICGGMYSGKSEELIRRVRRAQIAKQKVQVFKHSLDIRYDKDYVASHTGLKIEAIPVSSSADIERLVKDDTQVVAIEEGQFFDMGLVKVCQRLADRGKRVIVAGLDQDFRGEPFGPMPYLMAVAEYVDKLHAICMKCGNVASRTQRIIDGKPAYYDDPIILVGAFETYEARCRHCHVVLRREEDEK
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISOA_PSEUM
Sequence: MKCPKILAALLGCAVLAGVPAMPAHAAINSMSLGASYDAQQANITFRVYSSQATRIVLYLYSAGYGVQESATYTLSPAGSGVWAVTVPVSSIKAAGITGAVYYGYRAWGPNWPYASNWGKGSQAGFVSDVDANGDRFNPNKLLLDPYAQEVSQDPLNPSNQNGNVFASGASYRTTDSGIYAPKGVVLVPSTQSTGTKPTRAQKDDVIYEVHVRGFTEQDTSIPAQYRGTYYGAGLKASYLASLGVTAVEFLPVQETQNDANDVVPNSDANQNYWGYMTENYFSPDRRYAYNKAAGGPTAEFQAMVQAFHNAGIKVYMDVVYNHTAEGGTWTSSDPTTATIYSWRGLDNTTYYELTSGNQYFYDNTGIGANFNTYNTVAQNLIVDSLAYWANTMGVDGFRFDLASVLGNSCLNGAYTASAPNCPNGGYNFDAADSNVAINRILREFTVRPAAGGSGLDLFAEPWAIGGNSYQLGGFPQGWSEWNGLFRDSLRQAQNELGSMTIYVTQDANDFSGSSNLFQSSGRSPWNSINFIDVHDGMTLKDVYSCNGANNSQAWPYGPSDGGTSTNYSWDQGMSAGTGAAVDQRRAARTGMAFEMLSAGTPLMQGGDEYLRTLQCNNNAYNLDSSANWLTYSWTTDQSNFYTFAQRLIAFRKAHPALRPSSWYSGSQLTWYQPSGAVADSNYWNNTSNYAIAYAINGPSLGDSNSIYVAYNGWSSSVTFTLPAPPSGTQWYRVTDTCDWNDGASTFVAPGSETLIGGAGTTYGQCGQSLLLLISK
What are the official names of this protein?
Isoamylase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: PA2A_CROAD
Sequence: MRTLWIVAVLLLGVEGSLVQFETLIMKVAKRSGLLWYSAYGCYCGWGGHGRPQDATDRCCFVHDCCYGKATDCNPKTVSYTYSEENGEIVCGGDDPCGTQICECDKAAAICFRDNIPSYDNKYWLFPPKNCREEPEPC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 beta, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HC173_ARATH
Sequence: MVGSIVGSNMAATDARFLSSNFGNSFSINTRIHRFHDRSQIVIPRAQSSSSPSPSPPSDKKKTKTRPGTITTKESEETVAKKLDVAPPSPQSPPSPPTLKLDDVNPVGLGRRSRQIFDEVWRKFSGLGQMSRTTRPDEQETLDSLLIREGPMCEFAVPGAQNVTVLVVGATSRIGRIVVRKLMLRGYTVKALVRKQDEEVMSMLPRSVDIVVGDVGEPSTLKSAVESCSKIIYCATARSTITADLTRVDHLGVYNLTKAFQDYNNRLAQLRAGKSSKSKLLLAKFKSAESLDGWEIRQGTYFQDTTASKYDGGMDAKFEFTETERAEFSGYVFTRGGYVELSKKLSLPLGTTLDRYEGLVLSVGGNGRSYVVILEAGPSSDMSQSKQYFARISTKAGFCRVRVPFSAFRPVNPEDPPLDPFLVHTLTIRFEPKRQRPVDGLAGAQQDLRSFSLVFEYIKALPAGQETDFILVSCTGSGVEANRREQVLKAKRAGEDSLRRSGLGYTIIRPGPLKEEPGGQRALIFDQGNRISQGISCADVADICVKALHDSTARNKSFDVCHEYVAEQGIELYELVAHLPDKANNYLTPALSVLEKNT
What is the function of this protein?
Auxiliary factor required, together with HCF244, for the biogenesis of photosystem II (PSII), especially for the synthesis of the reaction center proteins (e. g.  D1), via the regulation of the corresponding mRNA (e. g.  psbA) translation initiation (ribosomal loading) and stabilization.
What are the official names of this protein?
Protein HIGH CHLOROPHYLL FLUORESCENCE PHENOTYPE 173, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Plastid, chloroplast stroma. Note=Predominantly present at thylakoid membranes.
Protein: FUT9_RAT
Sequence: MTSTSKGILRPFLIVCIILGCFVACLLIYIKPTNSWVFSPMESASSVLKMKNFFSRKTDYFNETTILVWVWPFGQTFDLTSCQAMFNIQGCHLTTDRSLYNKSHAVLIHHRDISWDLTNLPQQARPPFQKWIWMNLESPTHTPQKSGIEHLFNLTLTYRRDSDIQVPYGFLTVSTSPFVFEVPSKEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQAFGEYVNDKNLIPTISTCKFYLSFENSIHKDYITEKLYNAFLAGSVPVVLGPSRENYENYIPADSFIHVEDFNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal lactosamine unit of a glycoprotein or a glycolipid-linked polylactosamine chains through an alpha-1,3 glycosidic linkage and participates in particular to the Lewis x (Lex)/CD15 epitope biosynthesis in neurons which allows cell differentiation, cell adhesion, and initiation of neurite outgrowth (PubMed:11020213, PubMed:11675393).  Also fucosylates di-, tri- and tetraantennary N-glycans linked to glycoproteins and the inner lactosamine unit of the alpha2,3-sialylated polylactosamine resulting in sLex (CD15s) epitope synthesis.  Furthermore, it is capable of synthesizing Lewis a (Lea), although to a lesser extent than Lex and Lewis y (Ley) and to confer SELE-dependent, but not SELL- and SELP-selectin-dependent, cell rolling and adhesion by enhancing Lex and sLex synthesis (By similarity).  May also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE.
What are the official names of this protein?
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, Fucosyltransferase 9, Fucosyltransferase IX, Fuc-TIX, FucT-IX, Galactoside 3-L-fucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Golgi apparatus membrane.
Protein: ATF6A_MOUSE
Sequence: MESPFSPVLPHGPDEDWESTLFAELGYFTDTDDVHFDAAHEAYENNFDHLNFDLDLMPWESDLWSPGSHFCSDMKAEPQPLSPASSSCSISSPRSTDSCSSTQHVPEELDLLSSSQSPLSLYGDSCNSPSSVEPLKEEKPVTGPGNKTEHGLTPKKKIQMSSKPSVQPKPLLLPAAPKTQTNASVPAKAIIIQTLPALMPLAKQQSIISIQPAPTKGQTVLLSQPTVVQLQSPAVLSSAQPVLAVTGGAAQLPNHVVNVLPAPVVSSPVNGKLSVTKPVLQSATRSMGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGSLKRQLDEVVSENQRLKVPSPKRRAVCVMIVLAFIMLNYGPMSMLEQESRRVKPSVSPANQRRHLLEFSAKEVKDTSDGDNQKDSYSYDHSVSNDKALMVLSEEPLLYMPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNSQQKARILQGALEQGSNSQLMAVQYTETTSISRNSGSELQVYYASPGSYQGFFDAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININDNVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDHQRNQTSTFFGSPPTTTETTHVVSTIPESLQ
What is the function of this protein?
Transcription factor that initiates the unfolded protein response (UPR) during endoplasmic reticulum stress by activating transcription of genes involved in the UPR.  Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3').  Binding to ERSE requires binding of NF-Y to ERSE.  Could also be involved in activation of transcription by the serum response factor.  May play a role in foveal development and cone function in the retina.
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha, Activating transcription factor 6 alpha, ATF6-alpha.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Translocates from the endoplasmic reticulum to the Golgi, where it is processed. SUBCELLULAR LOCATION: [Processed cyclic AMP-dependent transcription factor ATF-6 alpha]: Nucleus. Note=Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus (PubMed:22682248). THBS4 promotes its nuclear shuttling (PubMed:22682248).