PharMolix/UniProtQA huggingface dataset:
Protein: ATP5J_PONAB
Sequence: MILQRLFRFSVIRSAVSVYLRRNIGVTAVAFNKELDPIQKLFVDKIREYKSKRQTSGGPVDAGPEYQQELEKELFKLKQMFGNADMNTFPAFKFEDPKFEVIEKPQA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.  Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes (By similarity).
What are the official names of this protein?
ATP synthase-coupling factor 6, mitochondrial, ATPase subunit F6, ATP synthase peripheral stalk subunit F6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase subunit F6 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: HS90B_XENLA
Sequence: MPEVAHNGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNRLERTLTMIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVKVDTGEPIGRGTKVILHLKEDQTEYLEEKRVKETVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKEEKKEEEGENDKPKIEDVGSDEEEEGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFVRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFCELAEDKENYKKFYEGFSKNLKLGIHEDSTNRKKLSELLRYHTSQTGDEMASLTEYVSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKTMEENKTKFESLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPEHPIVETLRQKADTDKNDKAVKDLVVLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDAPIEEASPSVPDDIPPLEGEEDASRMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.  Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself.  Recruitment of ATP and co-chaperone followed by client protein forms a functional chaperone.  After the completion of the chaperoning process, properly folded client protein and co-chaperone leave HSP90 in an ADP-bound partially open conformation and finally, ADP is released from HSP90 which acquires an open conformation for the next cycle.
What are the official names of this protein?
Heat shock cognate protein HSP 90-beta.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle.
Protein: RL10_SODGM
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLMRRVVEGTPFECLKDTFVGPTLIAFSNEHPGAAARLFKAFAKDNANFEVKAAAFEGEVISASQIDRLATLPTYEEAIARLMSAMKEASAGKLVRTLAALRDQKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CAPSD_TTVA1
Sequence: MAYGWWRRRRRRWRRWRRRPWRRRWRTRRRRPARRRGRRRNVRRRRRGGRWRRRYRRWKRKGRRRKKAKIIIRQWQPNYRRRCNIVGYIPVLICGENTVSRNYATHSDDTNYPGPFGGGMTTDKFTLRILYDEYKRFMNYWTASNEDLDLCRYLGVNLYFFRHPDVDFIIKINTMPPFLDTELTAPSIHPGMLALDKRARWIPSLKSRPGKKHYIKIRVGAPRMFTDKWYPQTDLCDMVLLTVYATAADMQYPFGSPLTDSVVVNFQVLQSMYDKTISILPDEKSQREILLNKIASYIPFYNTTQTIAQLKPFIDAGNVTSGATATTWASYINTTKFTTATTTTYAYPGTNRPPVTMLTCNDSWYRGTVYNTQIQQLPIKAAKLYLEATKTLLGNTFTNEDYTLEYHGGLYSSIWLSPGRSYFETTGAYTDIKYNPFTDRGEGNMLWIDWLSKKNMNYDKVQSKCLISDLPLWAAAYGYVEFCAKSTGDQNIHMNARLLIRSPFTDPQLLVHTDPTKGFVPYSLNFGNGKMPGGSSNVPIRMRAKWYPTLFHQQEVLEALAQSGPFAYHSDIKKVSLGMKYRFKWIWGGNPVRQQVVRNPCKETHSSGNRVPRSLQIVDPKYNSPELTFHTWDFRRGLFGPKAIQRMQQQPTTTDIFSAGRKRPRRDTEVYHSSQEGEQKESLLFPPVKLLRRVPPWEDSQQEESGSQSSEEETQTVSQQLKQQLQQQRILGVKLRLLFNQVQKIQQNQDINPTLLPRGGDLASLFQIAP
What is the function of this protein?
Self-assembles to form an icosahedral capsid with a T=1 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins.  The capsid encapsulates the genomic DNA.  Capsid protein is involved in attachment and entry into the host cell (By similarity).
What are the official names of this protein?
Capsid protein.
What is the protein family that this protein belongs to?
Belongs to the anelloviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ATPL_MICAN
Sequence: MNPTVAAASVIAAALAVGLAAIGPGVGQGTASGEAVSGIARQPEAEGRIRGTLLLSLAFMESLTIYGLVIALVLLFANPFA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RS16_BARBK
Sequence: MALKIRLSRGGSKKRPYYHIVVADARSPRDGRFLERVGAWDPMLPKDKPRVKLNEDRIQHWLNQGAQPTDRVLRFLDAAGLKKRPARNNPHKGEPGKKAQERIAAAKQAAEDAKAAEASA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TRUB_THET2
Sequence: MALYAVDKPLHLTSHDVVEEARRRLSTRRVGHTGTLDPLATGLLLLVTNESTKLVPFLSGEDKEYIAWVSFGATTPTLDAEGPISEEAPARFDRKDLEAALPRFLEVREQVPPLYSAIKVGGKRAYEAAREGKPLALGPRPVRYLEVELLAFDPEPIPHPIAPSARGWRLAERRGRPVRLPRPLGAYPTAVVRLVVGPGTYVRAFARDLGEMLGTKAFLSGLVRTRVGRVGLERAVALSDLSPEKAIPELDVLPFPVVELSHTEARRVLEGMPLPIPAMGYVTLVDSKRRLLAIAEGDGFKLKIRRVFAKEA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: TCTP_BRUMA
Sequence: MLIFKDAFTDDELASDSFPMKLVDGLIWEFKGRQVVRREGEIQLAGANPSAEGEDGDEGSEECVERGIDFVLNHRLQEMNCYEDLVTFKSYCKSFMKKVVELMQKNGKSEAEISEFKRKIPAWVVSLLSKDRFKQLQFFIGERMAEGQGEGQVAVVEYRDEEDGEVPYLMLVKEALIEEKQ
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP, TPH-1.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_CITK8
Sequence: MDKFRVQGPTTLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDIDTTMKLLSQLGTKVERNGSVWIDASQVNIFCAPYELVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTANFLVTLGAKISGQGTDRITIEGVERLGGGVYRVLPDRIETGTFLVAAAISGGKIVCRNAQPDTLDAVLAKLRDAGADIETGEDWISLDMHGQRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETIFENRFMHVPELIRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTLVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_VIBVY
Sequence: MTTASNTPLPSGLRKPLDQFYEYLRAEKGLSLHTQRNYKQQLETMAEHLHSMGLKAWPQVDAGWVRQLAGKGMREGMKASSIATRLSSLRSFFDFLILRGILTANPAKGVSAPRKKRPLPKNLDVDEVNQLLEVNEDDPLAIRDRAIMELMYGAGLRLAELVDIDVRDVHLRSGEIRVIGKGNKERKVPFAGMAVEWVGKWLKVRSGLADPSEPALFVSKLGTRISHRSVQKRMAEWGQKQAVASHITPHKLRHSFATHILESSNNLRAVQELLGHENISTTQIYTHLDFQHLADVYDQAHPRARKKSSQHKEEDE
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK19_TRICV
Sequence: MLSLNTQKTIDNLHNVFTKKNIPPIRIGDNVKVGVRIIEGNKERVQFYEGTVIAKKNSSINTTLTVRKVLQGIGVERIFLIHSPKVDSIEVLRSSKVRRSKLYYLRNLKGKASRLKQQFR
What are the official names of this protein?
50S ribosomal protein L19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AROA_LEGPL
Sequence: MLNFISKPVGCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSMGVRIEGPDKQRVIIHGVGKYGLKQPQNIIDCGNSGTSMRLLAGLLAAQQFDSQLTGDESLLKRPMLRISRPLSQMGADVTTQDGKPPIVIKGGKKLNGVHYVMPEASAQVKSCLLLAGMYAEGQTKITENAVSRDHTERMLRTFSYPVQIQDGTIVIDRNGECHGTRLNIPGDISSAAFFIVAASITPDSDVLIRNVGINPTRTGIIHILTEMGADIRILNQRAYGEEPVADLHIRYSQLKGIDIPVSMVPLAIDEFPVIFIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVHAEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVASAPVTIKNCANVATSFPSFVTTANMLHFQIEEYS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_FRACC
Sequence: MGTEAGSAPVVRGRGLKVHHLRPAPGAHKSKIRVGRGEGSKGKTAGRGTKGSKARKQVPARFEGGQMPLHMRLPKLKGFRNRFRVEYQVVNVATLAELFPQGGEVTKADLAARGAVRGKSPVKVLGNGDINVALHVSADAFSASAKEKIAAAGGSVTQS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PSUG_SOLUE
Sequence: MHLKIDPEVRRALQGKRPVVALESTIITHGMPYPENLATARSLESQVRAGGAVPATIAVIGGVICVGLSDKELEWLAGAKNVLKLSRNDLPYAIATQKIGATTVAATMIAANLAGIRIFATGGIGGVHRGAETTFDISADLEEFARTSVAVVCAGAKAILDLPKTLEYLETRGVPVIAYGTDEFPAFWSRQSGLKAPLRLDTPAEIARFLEVKWSLNLTGGAVICNPVPAEDEIPFHEMRTFIDSAVDEAERYGIKGKAVTPYILARIVELTGGRSLRTNMALAQNNARLAAELATHLQ
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: MEPA_YERPS
Sequence: MKNWIVGMVALVTMVPVMAATPWQKITHPVAGSPQSIGGFANGCVIGAQPLPLESADYQVMRSDQRRYFGHPDLLNFIHRLSAQAHQQQLGTVLIGDMAMPAGGRFSSGHASHQSGLDVDIWLQLPKQRWSQQQLLKPQPIDLVAVDGKRVIPALWQPQIESLIKLAAKDNDVTRIFVNPAIKKQLCLDAGADRQWLHKVRPWFAHRAHMHVRLRCPANSLECVDQDTPPPGDGCGAELESWFQPPPPSAKPGKTLPPPLPPSCQALLDNHFATE
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: BGLT_THEMA
Sequence: MRIAVIGGGSSYTPELVKGLLDISEDVRIDEVIFYDIDEEKQKIVVDFVKRLVKDRFKVLISDTFEGAVVDAKYVIFQFRPGGLKGRENDEGIPLKYGLIGQETTGVGGFSAALRAFPIVEEYVDTVRKTSNATIVNFTNPSGHITEFVRNYLEYEKFIGLCNVPINFIREIAEMFSARLEDVFLKYYGLNHLSFIEKVFVKGEDVTEKVFENLKLKLSNIPDEDFPTWFYDSVRLIVNPYLRYYLMEKKMFKKISTHELRAREVMKIEKELFEKYRTAVEIPEELTKRGGSMYSTAAAHLIRDLETDEGKIHIVNTRNNGSIENLPDDYVLEIPCYVRSGRVHTLSQGKGDHFALSFIHAVKMYERLTIEAYLKRSKKLALKALLSHPLGPDVEDAKDLLEEILEANREYVKLG
What is the function of this protein?
Hydrolyzes cellobiose 6'-phosphate into glucose 6-phosphate (Glc6P) and glucose.
What are the official names of this protein?
6-phospho-beta-glucosidase BglT.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 4 family.
Protein: YHAM_ECO45
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAISDAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVTEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGNWGLHIGATLEKQCARGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: AOX_PODAS
Sequence: MISSKTSNRICLCSPQQTARITGIVVSSRPAYLTGLGYPVSLRLSSAVSQSSSQHTRSFSSTRAAHLKDFFPVKETAYIRKTPPAWPHHGYTEEEMLAVVPQHRKPGSLSDWLAWKLVRLCRWGTDIATGIKPEQQVDKSNPTTAVAAQKPLTEAQWLVRFIFLESIAGVPGMVAGMLRHLESLRRLKRDNGWIETLLEESYNERMHLLTFMKMCEPGWFMKTMILGAQGVFFNAMFLSYLISPRITHRFVGYLEEEAVHTYTRCIREIEQGDLPKWSDPNFQIPDLAVTYWKMPEGKRTMRDLILYIRADEAVHRGVNHTLSNLNHKEDPNPFVSDYKCDADHQRPNPALKPTGFERSEVIG
What is the function of this protein?
Catalyzes cyanide-resistant oxygen consumption.  May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity).
What are the official names of this protein?
Alternative oxidase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the alternative oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: MOAA_CROS5
Sequence: MNRVDYLRISLIDRCNFRCQYCMPEGAELDYILRQELLTHEELITLLKEVFIPLGFSKFRLTGGEPLLRPGIVDLVQDIASLPATEDLSMTTNGFLLSSLAEDLYQAGLKRINISLDSLNPDTFQTIIGHKKANMWQQTWLGIQTAYEVGFDPLKLNVVVIPGVNENEIEALAELSIHKNWHIRFIEFMPIGNPELFSDLEEIRFAGRAWVASEEIREKIRQKWGLIESNIKGNGPADVFKIPGAKGTVGFISQMSECFCDRCNRMRLSADGWLRPCLLNETGQIDLKTLLRSGISATNIRDKVAHLLTIKPDINYKQRDSGNDTGIYERTMSQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: FETP_FRATF
Sequence: MTKVFCKKYHQELDAIPFQPLPGELGKKIHNEISNKAWQAWLAHQTILINEYRLNLIEPKAKEFLKEEMYKFLFEGKEEKPEQFSEI
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: NCBP2_CULQU
Sequence: MTSVHTPSVALSKYRDQHFKGSRHEQERLLRNSSTLYIGNLSFYTTEEQIHELFSRCGDIRRIVMGLDKFKKTPCGFCFVEYYARIDSEYAMRYINGTRLDDRIVRVDWDAGFVEGRQYGRGKTGGQVRDEYRQDHDLGRGGYGKMVAMGQLGAPNMRES
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing.  Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires Cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPE_YERPE
Sequence: MICPVIELAQQLIKRPSLSPSDAGCQEIMIQRLAAIGFTIEPMNFGDTLNFWAWRGEGETLAFAGHTDVVPTGDESHWHSPPFEPTIRDGMLYGRGAADMKGSLAAMIVAAERFVAAHPDHKGRLAFMITSDEEAKATNGTVKVVEALMARHERLDYCLVGEPSSTDRVGDIVKNGRRGSITANLRIHGVQGHVAYPHLADNPVHRAMPALNELVATQWDEGNAFFPATSMQIANLQAGTGSNNVIPGEFYVQFNFRFSTELTDSLIKQRVAALLDRHQLDYTLEWVLSGQPFLTAKGALVDAVVNAVKHYTEITPQLLTTGGTSDGRFIALMGAQVVELGPVNATIHKVNECVSAADLQLLSRMYQKIMEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: HRCA_STRZJ
Sequence: MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDMAELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLEDILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQFLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFEHIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADGQESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYRYLSSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: DELE1_RAT
Sequence: MWRLTGILGRALPRLLGPGFRGITPKPTSSDGPQTTSTTLPLPRVNFDRSGSHGSKRNRDPKCCGWKEAFHWMSAHVSPNTLRDAVSWGTLAVLALHLARQIHFHAPLVAGPQSAERCSWHSPLYRFLSSSWWHPHSSLRRHVLPSPDCPAPRNTGLREPRLGQEEPAARSQGLPSDSSLKPGLLNLPEEEPSDFGFLNASRDFTSQAKAAEAGPPGGKNEQDKPKALPLEEAVTSIQQLFQLSVAIAFNFLGTENIKTGDYTAAFSYFQKAADRGYSKAQYNVGLCLEHGRGTPRDLSKAVLFYHLAAVQGHSLAQYRYARCLLQSPGSMSDPERQRAVSLLKQAADSGLTEAQAFLGVLFTKEPHLDEQKAVKYFWLAASNGDSQSRFHLGICYEKGLGVQRNLGEAVKCYQKSAAMGNEPAQERLRTLFNVEAAGPSHLAIGLKSFSSPSLCSLNTFLAGASGLPHASSTGNLGLLCRSGHLGTSHGAPSRAMPSLERSLVRLGFG
What is the function of this protein?
Protein kinase activator generated by protein cleavage in response to mitochondrial stress, which accumulates in the cytosol and specifically binds to and activates the protein kinase activity of EIF2AK1/HRI.  It thereby activates the integrated stress response (ISR): EIF2AK1/HRI activation promotes eIF-2-alpha (EIF2S1) phosphorylation, leading to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, the master transcriptional regulator of the ISR.
What are the official names of this protein?
DAP3-binding cell death enhancer 1, DAP3-binding cell death enhancer 1, long form, DELE1(L), Death ligand signal enhancer.
What is the protein family that this protein belongs to?
Belongs to the DELE1 family.
What are the subcellular locations of this protein?
[DAP3-binding cell death enhancer 1]: Mitochondrion. Mitochondrion inner membrane. Note=Associates with the mitochondrion inner membrane in response to mitochondrial stress, leading to its proteolytic processing by OMA1, and generation of the AP3-binding cell death enhancer 1 short form (DELE1(S) or S-DELE1). SUBCELLULAR LOCATION: [DAP3-binding cell death enhancer 1 short form]: Cytoplasm, cytosol. Note=This short form is generated by proteolytic processing by OMA1 in response to mitochondrial stress, leading to translocation to the cytosol.
Protein: RL31_COXB2
Sequence: MKENIHPPYKQIKVTCSCGNTFMTGSTLDRELHLEICSACHPFYTGQQKMVDTAGRVERFRKKYAKRRAANASPEDEKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: M3F_CONTE
Sequence: MSKLGVLLTICLLLFPLTALPLDGDQPADQAAERMQAEQHPLFDQKRRCCKFPCPDSCRYLCCG
What are the official names of this protein?
Conotoxin Tx3.5-a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_LEPIC
Sequence: MSTEALLEQIGKLTLVEAADLVKKMEDKFGISAAAPVAVAAVGAAPAGAGAAEEASTFNVILKGFDSAKKIEVIKLVREITGLGLADAKGLVEAGGKAVKEGVAKAEADDLKKKFEGAGAQIELKAS
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: KDSB_HAEI8
Sequence: MSFTVIIPARFASSRLPGKPLADIAGKPMIQHVFEKALQSGANRVIIATDNENVADVAKNFGAEVCMTSVNHNSGTERLAEVVEKLAIPDNEIIVNIQGDEPLIPPVIVRQVADNLAKFNVNMASLAVKIHDAEELFNPNAVKVLTDKDGYVLYFSRSVIPYDRDQFMNLQDVQKVQLADAYLRHIGIYAYRAGFIKQYVQWAPTQLENLEKLEQLRVLYNGERIHVELAKEVPAVGVDTAEDLEKVRAILAAN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.