PharMolix/UniProtQA huggingface dataset:
Protein: RL15_RICCK
Sequence: MKLNELYNNIGAKKRKKRIARGIGSGKGKTGGRGIKGQKSRSGVAIKGFEGGQTPIIKRLPKRGFNCISTKKYNIVNIYNIEVALADGRLSVADIITKEKLIEAGVVNNKNNKKLVKLLSLCSDDFATPLSLKLDAYSSKAKDFIEQAGGKLL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: HXD3_RAT
Sequence: TGRTRAHRARHPRGCTAYTSAQLVELEKEFHFNRYLCRRRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPAGQSPERTPPLGGAAATCLLRPAAAVPAWPTTHPS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D3, Homeobox protein R6.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLS1_HUMAN
Sequence: MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW
What is the function of this protein?
Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane resulting in collapse of the phospholipid asymmetry which leads to phosphatidylserine externalization on the cell surface (PubMed:9218461, PubMed:8663431, PubMed:10770950, PubMed:9572851, PubMed:9485382, PubMed:18629440, PubMed:23590222, PubMed:24648509, PubMed:24343571, PubMed:32110987, PubMed:23659204, PubMed:29748552).  Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with TRPC5 (By similarity).  Also exhibits magnesium-dependent nuclease activity against double-stranded DNA and RNA but not single-stranded DNA and can enhance DNA decatenation mediated by TOP2A (PubMed:27206388, PubMed:17567603).  Negatively regulates FcR-mediated phagocytosis in differentiated macrophages (PubMed:26745724).  May contribute to cytokine-regulated cell proliferation and differentiation (By similarity).  May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes (PubMed:15308695).  Acts as an attachment receptor for HCV (PubMed:21806988).
What are the official names of this protein?
Phospholipid scramblase 1, PL scramblase 1, Ca(2+)-dependent phospholipid scramblase 1, Erythrocyte phospholipid scramblase, Mg(2+)-dependent nuclease, MmTRA1b.
What is the protein family that this protein belongs to?
Belongs to the phospholipid scramblase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor; Cytoplasmic side. Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Localizes to the perinuclear region in the presence of RELT (PubMed:22052202). Palmitoylation regulates its localization to the cell membrane or the nucleus; trafficking to the cell membrane is dependent upon palmitoylation whereas in the absence of palmitoylation, localizes to the nucleus (PubMed:12564925).
Protein: HBB_POTTR
Sequence: VHLSSEEKGLITSLWGKIDIEQTGGEALGRLLIVYPWTSRFFDHFGDLSSAKAVLGNAKVLAHGAKVLVSFGDAIKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVICLAEHFGKDFTIDAQVAWQKLVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS16_BORA1
Sequence: MVVIRLARGGSKKRPFYNLVATDSRNRRDGRFVERVGFYNPVGSEGSENLRIALDRVKYWVDNGAQLSPAVERLVKEHSAKVSAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ACYP_BORAP
Sequence: MYKQQYFISGKVQGVGFRFFTEQVANNMKLKGFVKNLNDGRVEIVAFFNTKEQIKKFENLLKNGNRYSNIENIEKKTLDEKYPFQFNNFKIYY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: VF859_ASFP4
Sequence: MCAGFYVAVHPWLEAQSLHKVGHTGNLAARLHDGSYTTCFTDEWKYCFTLETSTKKDAQKIEAGVLYCAQFFRVKNKELVCLLPEKIKQLAEDVANCLDISYTLCDSPAYEMNDSTIVVEPSLPSDPLISKEKLRHLVITPVEDEEHFADDVLFFSTDETRTAIEDRLYQKEAANMGYQELRRSGRAILQMACRCGKTRVAYLILSNYLQGKVLYLVPGLSLLRQTLEKLYQYGISLKNVLLVGSDQTRIVLNHDNIEMTTNPVFIAKRIREAPSLLVIATYQSSTLLVDDFDLIISDECHRICGEWETRPFTHVLLNFKKGHRLFLTATPRYDTPLSMKNRELFGGVAFRYYLREGIEAGYVNDFELQMVAAPKLAHQPSTKEETTKQIIVKQIIMALAHLKTNITAPKMLVFTRDIKQAKELYAELVDQGVYALIAHSTLPRQVILKTFTEFCSSKEPVILLNCRLFQEGVEVPELNAVFFAAPRHSPRDIIQSICRPLNKQVQKPHATIFLPLEVNTENVCLDRFSSIIPFADALASEDPRFYEHLLNPSEVAYPINWIGAHGSVSELLQLARHAIRYGTQGKIDRLTRSERLPWKAAFAELKRTVEICCRYPKINDGFHFGGATLRFDTWYKWVIKSYLQYKNKEPSSLEPYQVSDLESLQDWTTRGVGGPYPWEESMAFLETWLAQNKGELVAIDIHQGGWIGLDATPMERLSGVLTTVSQRDGRSYGKNKKLRPKKGFMIPPQQAQDLDRIFGKHNLKWRKDRVNGFLKEDEHGNYTGEPTCIQEAYRTFKEYVKTNPEYIEKYWPGYAKGKHKHQELPHIWEKGLAPPRYKAFKDGNKQLIQRSPKKKDIKN
What are the official names of this protein?
Probable helicase A859L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus helicase A859L family.
Protein: OSPG_SHIF2
Sequence: MKITSTIIQTPFPFENNNSHAGIVTEPILGKLIGQGSTAEIFEDVNDSSALYKKYDLIGNQYNEILEMAWQESELFNAFYGDEASVVIQYGGDVYLRMLRVPGTPLSDIDTADIPDNIESLYLQLICKLNELSIIHYDLNTGNMLYDKESESLFPIDFRNIYAEYYAATKKDKEIIDRRLQMRTNDFYSLLNRKYL
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria (By similarity).
What are the official names of this protein?
Protein kinase OspG, Effector protein OspG.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Secreted. Host cell. Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cell.
Protein: DNLJ_PSEA8
Sequence: MTDTQAAAERIAQLRTELDTHNYRYYVLDEPSIPDAEYDRLFRELQALEAEYPQLLTPDSPTQRVSGTPASAFGEVRHEIPMLSLGNAFEEQDLLDFDRRVREGLADLLPGGDLLGGGAEVEYSCEPKLDGLAVSLLYERGQLVRGATRGDGSTGEDITSNVRTIRNVPLKLHGEGWPEILEVRGEVFMSKAGFEALNAKAVETGGKTFANPRNAAAGSLRQLDSKITASRPLEFCAYGFGQVSGTLPDTQVGILEAFRGWGIPISRELRLVKGAQACRDYYDDIGRRRDALAYEIDGVVFKVNRIAFQRELGFRAREPRWAIAHKFPAREELTELLGVEFQVGRTGAVTPVARLKPVQVAGVTVSNATLHNMDEVARLGLRIGDTVVIRRAGDVIPQVMQVVLERRPADAQAIEVPEHCPVCGSAVERTQLVKRSKGKESISEGAIYRCVGRLSCQAQLKQAIIHFVSRRAMDIDGLGDKIVEQLVDRGLVASPADLYTLTYEQVFELEGFAELSTNNLLTAIADSRKPSLARFIFALGIPDVGEETAKLLARSLGSLERIGKALPEVLTYLPDVGAEVAYEIHNFFADEHNRQVIAQLRDAEHGVQLQEEGEVAAEFAACASLAGFIDKLNIPFIAATGAEKLASRFGSLDGIIRADWLDLRQVERLPERAAKSLRDFFDEPANVQRALAIEAQLREFGMHWQSERKAVEGLPLAGQTWVLTGTLEAMSRDVAKDKLEGLGAKVAGSVSAKTHCVVAGPGAGSKLAKANELGVKVLDEDGLLKLFDEHGVAR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PSTA_MYCGE
Sequence: MQKKIKKRLKKENLLRIFSKTLAFLFLVLFISFFVFLLTEATKIGPDFAKSLFNLEFNLGNKQAGIWFPLLVSFIVSIGALIIASYIGVRTSFFLVYRCKPKIRKKLSLIIDILSGIPSVIFGLFASQILSIFFRDILKLPPLSLLNVIAMLSFMIIPIVISLTTNTLTYVNNDLISVVVSLGENKTSAIYKIIKKEIKPQLTVILTLAFARAISETMAVNFVLQSVNYQEVINNNRFFTSDLKTLGSVISTFIFSENGDEQINGVLYIFGIIILILVSLLNFFAIWSANPKTLERYPFLKKISNFIYQVVWFIPNNISALFVDLTSTRQSVKKIKVNNINERSLFFKERLQSVVWIKLNYFLKIFQELICTFLAFGFVLAILLFVFINGSVAINNNGSTVFSFEADSTGRALVNTLVIILITITITFPLALLIAIWLNEYNNSKVVKNVFNFVIDSLSSMPSIIYGLFGLSFFLRVLQLSAGGANGTSLIAGILTISVVILLFLIRTCQQALNNVSWDLRISAFALGISKREVIFKIVLPSALKGLIVALILSINRIIAETAPFFITSGLSSSNLFHLSLPGQTLTTRIYGQLFSINSNAISVMLETSLVSVVFLILLIFFSSYLIPSLFLLNKQKWLVIKSKFQSFKLWKRT
What is the function of this protein?
Could be part of a binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphate transport system permease protein PstA homolog.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OPGG_BRADU
Sequence: MNRRQLLRGSVAVSAAAVLPRAADAQSGTALTFSPSYVRELARALATKPFAAPDEKLPEALKNLNYDQYRSIRFAPEKALWRAEKLPFEVQFFHRGFFYKNRVDIFQVADRSVTPVSYRRDDFSFGEGLGQWPDADLGFAGFRIHAPINKPDYYDELCVFLGASYFRVVAKGQTYGLSARGLAIDTGESKGEEFPVFKAFWLEKPAPSASSMVVHALLDSKSAAASYRFTIRPGQTTVFDVEMALYPRVDLEHAGLAPMTSMFFFGPNDRKDFDDFRPAVHDSDGLSIFNGRGEQLWRPLNNPHDLQVSSFTDVNPGGFGLMQRERNYLAYQDLESSFETRPSLWFEPIGDWGEGAVKLFEIPTKEEVHDNIAALWQPKQPLTAKSEHIFTYRLHWGADAPRADALARFTRTGIGSRGDDSKLFVLELTGDRLKGVDPKTIKGVVTAEKADISNIVTQPNPATGGWRLSFQCSVKGQASIELRAFLAQNDAPVSEVWIYRWTP
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PDXH_ERYLH
Sequence: MQSEESIMTDLATSEIPETDPFALFAEWMEEARASELNDPNAMALATATPDGAPSVRMVLLKDHGPQGFTFYTNAESRKGEEIRANAQTALLFHWKSLRRQIRVEGPVREVAPEVADAYFHSRARESQLGAVASDQSRPLEDRRVFVDRFRAAQERFDEGEVERPAYWTGFTVTPQRIEFWCDRPNRLHDRRLFTLSGAGDALSWTSTLLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: Y1068_FINM2
Sequence: MKIIISPAKTFKIRKLKKENIDCLFENKKNALVSIMKEKSIEELKSMWKCSDKIAEESYKLYKNFDVSPKGCAIRSFDGIQYQYMDVDSLDEDKLEYLEEHLRILSGLYGILRPFDQISKYRLDFEDKFINLYEFWEDEIRNHFEGEEIIDLASKEYGQNIYKYLDKAPVKIEFKEEVLIDGDIKLKTKATPSKILRGRMVNYMARNHIENIEQLKKFSCDGYNYSEKNSDKKKLVFVKSLVSE
What are the official names of this protein?
UPF0246 protein FMG_1068.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RL34_THEBO
Sequence: MKRTWQPNRRKRAKTHGFRARMKTPGGRKVLKRRRQKGRWRLTPKVNA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RRP5_MOUSE
Sequence: MANLEESFPRGGTRKLHKSEKSSQQVVEQDNLFDVSTEEGPIKRKKSQKGPAKTKKLKIEKRKSIKSIKEKFEILSLESLCEGMRILGCVKEVSELELVVSLPNGLQGFVQVTEVCDAYTQKLNEQVAQEEPLEDLLRLPELFSPGMLVRCVVSSLDVTESGKKSVKLSVNPKRVNKVLSADALRPGMLLTGTVSSLEDHGYLVDIGVGGTRAFLSLKKAQEYIRQKNKGAKFKVGQYLTCVVEEVKSNGGVVSLSVEHSEVSSAFATEEQSWNLNNLLPGLLVKAQVQKVTQFGLQLNFLTFFKGLVDFMHLEPKKMGSYSSNQTVKACILCVHPRTRVVRLSLRPIFLHPGRPLTRISYQQLGAVLDDVPVQGFFKNAGAIFRLKDGVLAYARVSHLSDSKKAFNAEAFKPGSTHKCRIIDYSQMDELALLSLRKSIIAAPFLRYHDIKIGTVVKGTVLAIKPFGILVKVGEQIKGLVPSMHLADIMMKNPEKKYSPGDEVKCRVLLCDPEAKKLIMTLKKTLVTSKLSLITCYEGAKPGLQTHGVIIRVKDYGCIVKFYNDVQGLVPKHELSTQHIPDPETVFYTGQVVKVAVLSCEPSKERMLLSFRLLSDSRPKDPGVESSQKKTGAVRIGQLVDVKVLEKTKTGLEVAILPHNTPAFLPTPHLSDHAANGPLLHHWLQTGDTLHRVLCLSQSERHILLCRKPALVSTVEGGQDPKSLSEIQPGMLLIGFVKCIKEYGVFVQFPSGLSGLSPKTIMSDKFVTTPSEHFVEGQTVVAKVTNVDESKQRMLLSLRLSDCSLGDSASTSFLLLCQCLEELQGIRSLMSNQDSVLIQTLADMTPGMVLDAVVHEVLEDGSVVFSSDPVPDLVLRASRYHRAGQEVEPGQKKKVVVLHVDMLKLEVHVSLHQDLVNRKTRKLRKSSRHQGIVQHLEESFAVASLVETGHLVAFSLISHLNDTFHFDSEKLRVGQGVCLTLKTTEPGVTGLILAVEGPASKRTRMPVQRDSETVDDKGEEKEEEEEEEEKEEENLTVKSKKRHSLAIGDKVTGTIKAVKATHVVVTLADGFVGCIHASRILDDVPVGTSPTTTLKAGKKVTARVIGGRDVKTSKFLPISHPRFVLTILELSVRPSELKGSYSALNTHSESPVEKIRQYQAGQTVTCFFKKYNVMKKWLEVDIGPDIRGRIPLLLTSLSFKVLKHPDKKFQVGQAIEATVVDPDVPRAFLCLSLIGPYRLEEGEVAMGRVMKVVPNRGLTVSFPFGKIGKVSMFHLSDSYSEAPLEDFCPQKIVRCYILSTAHRVLALSLRSSRTNRETKNRIEDPEINSIEDVKEGQLLRGYVKCVLPSSVIIGLGPSVLGLAKYSHVSECVPPEKELYNGCLPEGKLVTAKVLRVNPMKNLIELSLLPSDTGRPDVFSPAPEPKQEERSGGAEEGQKRKEKNQKRREEKEEPQKSQRGGRGKRERQESESEQELVNKRPKKSGAAEEDDSGVEVYYREGEDEVGEPKLPPRGKQTKSTEVPRLHLSSGFLWDVGLDSLTPALPLREESSDSEDEQPHQAKKKKGKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKYKEAGELYNRMLKRFRQEKAVWIKYGAFVLGRSQAGASHRVLQRALECLPAKEHVDVIVKFAQLEFQLGDVERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQTAVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSALED
What is the function of this protein?
Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor.  Directly interacts with U3 snoRNA (By similarity).
What are the official names of this protein?
Protein RRP5 homolog, Apoptosis-linked gene 4 protein, Programmed cell death protein 11.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MDAR_SOLLC
Sequence: MAEKSFKYVIVGGGVSAGYAAREFAKQGVKPGELAIISKEAVAPYERPALSKAYLFPEGAARLPGFHVCVGSGGERQLPEWYAEKGISLILSTEIVKADLASKTLVSAAGESFKYQTLVIATGTTVLKLSDFGVQGADSKNIFYLREIDDADQLVEALKAKKNGKAVVVGGGYIGLELSAVLRLNNIEVNMVYPEPWCMPRLFTEGIAAFYEGYYKNKGVNIIKGTVAVGFDTHPNGEVKEVKLKDGRVLEADIVVVGVGARPLTTLFKGQVEEEKGGIKTDAFFKTSVPDVYAVGDVATFPLKMYNEIRRVEHVDHSRKSAEQAVKAIFASEQGKSVDEYDYLPYFYSRAFDLSWQFYGDNVGETVLFGDADPNSATHKFGQYWIKDGKIVGAFLESGSPEENKAIAKVAKVQPPATLDQLAQEGISFASKI
What is the function of this protein?
Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process.
What are the official names of this protein?
Monodehydroascorbate reductase, MDAR, Ascorbate free radical reductase, AFR reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_FRATT
Sequence: MKATQTLIATTKELPKEAVLISHQYMLKAGLIKKLASGIYTWMPLGLKVLQKIQNIVRDEMNKAGASELLLPSILPSELLQETHRWDKFGPELLKLHDRHNRDFCYGPTHEEPIVDMARDTIKSYKQLPLNLYQIQTKFRDEIRPRFGVMRAREFIMKDAYSFHENSQCLRNTYNTMYATYCNILDKIGLAYRPVKADTGAIGGDNSHEFQVLANAGEDIICYSNGSDYAANIELATYAKSDLSKRVNSQNTIEKIHTPNIKTIEKLCKEMSFDIKKTIKTMVIKDAGGNFFALVIRGDHELNETKINKLDQIIAPYTLATKEEIFSIFNANPGSLGIYNCPISIIADYSAIAITDLVCGANEDDYHFTNVNWDRDVTNYQIADIRNVVTGDISPDGKGTLELTNGIEVGHIFELEDVYSKPMNANIIGQDGKSKPMLMGCYGFGVSRVMAAAIEQSHDENGIIWPESIAPYQVAILPINYNKSDKIKEVADKLYQDLLGDGIDVLLDDRGARPGVMFADADLIGYSHHVVIGDRLLEQGLIEYKNRKTQEKQEITIAELIKILK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_NITOC
Sequence: MILLRHGESVWNLENRFTGWTDVDLSANGVEEARLAGKILKNEGYQFDKAYTSVLKRAIRTLWIVEEMMDLVWLPVEKRWELNERHYGNLQGLNKAEMAKQYGAELVHQWRRGYGIEPPPLDNSDPRHPRFDRRYAGLAPEALPASESLKKTLKRVIPCWKQHILPDIAAGKELIIVAHGNSLRALYKHLEGLSDQEVMELNIPTGIPLVFELDSAFRPTAHYYLADSEKSQVVIGDTAH
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: SUCC_ECOLI
Sequence: MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.  Can use either ATP or GTP, but prefers ATP.  It can also function in the other direction for anabolic purposes, and this may be particularly important for providing succinyl-CoA during anaerobic growth when the oxidative route from 2-oxoglutarate is severely repressed.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: FRIH_SHEEP
Sequence: MTTASPSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAERLMKLQNQRGARIFLQDIKKPDRDDWENGLNAMECALCLERSVNQSLLELHKLATEKNDPHLCDFIETHYLNEQVEAIKELGDHITNLRKMGALWIGHGRVPL
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  Also plays a role in delivery of iron to cells.  Mediates iron uptake in capsule cells of the developing kidney (By similarity).
What are the official names of this protein?
Ferritin heavy chain, Ferritin H subunit.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: GLO2_SALPK
Sequence: MNLNSIPAFQDNYIWVLTNDEGRCVIVDPGEAAPVLKAIAEHKWMPEAIFLTHHHHDHVGGVKELLQHFPQMTVYGPAETQDKGATHLVDDGDTIRVLGEKFTLFATPGHTLGHVCYFSHPYLFCGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTLICCAHEYTLANIKFALSILPHDSFINEYYRKVKELRVKKQMTLPVILKNERKINLFLRTEDIDLINEINKETILQQPEARFAWLRSKKDTF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CYC5_AZOVI
Sequence: GGGARSGDDVVAKYCNACHGTGLLNAPKVGDSAAWKTRADAKGGLDGLLAQSLSGLNAMPPKGTCADCSDDELKAAIGKMSGL
What is the function of this protein?
It is unreactive with cytochrome c reductase or oxidase.
What are the official names of this protein?
Cytochrome c5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
Protein: OR2T4_HUMAN
Sequence: MDNITWMASHTGWSDFILMGLFRQSKHPMANITWMANHTGWSDFILLGLFRQSKHPALLCVVIFVVFLMALSGNAVLILLIHCDAHLHTPMYFFISQLSLMDMAYISVTVPKMLLDQVMGVNKISAPECGMQMFFYVTLAGSEFFLLATMAYDRYVAICHPLRYPVLMNHRVCLFLSSGCWFLGSVDGFTFTPITMTFPFRGSREIHHFFCEVPAVLNLSCSDTSLYEIFMYLCCVLMLLIPVVIISSSYLLILLTIHGMNSAEGRKKAFATCSSHLTVVILFYGAAIYTYMLPSSYHTPEKDMMVSVFYTILTPVVNPLIYSLRNKDVMGALKKMLTVEPAFQKAME
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2T4, Olfactory receptor OR1-60.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDC10_HUMAN
Sequence: MRMTMEEMKNEAETTSMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFVSANRLIHQTNLILQTFKTVA
What is the function of this protein?
Promotes cell proliferation.  Modulates apoptotic pathways.  Increases mitogen-activated protein kinase activity and STK26 activity (PubMed:27807006).  Important for cell migration, and for normal structure and assembly of the Golgi complex (PubMed:27807006).  Important for KDR/VEGFR2 signaling.  Increases the stability of KDR/VEGFR2 and prevents its breakdown.  Required for normal cardiovascular development.  Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity).
What are the official names of this protein?
Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the PDCD10 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Partially co-localizes with endogenous PXN at the leading edges of migrating cells.
Protein: PPK25_SCHPO
Sequence: MKPNTTNLRNECWDTFSIPKRSQNIKINQSTKHQRSISDFVGTAGPGRQVGNWIIKKTIGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTVRVQREALLGRLLRHPNICRVIDCIRTPACTYILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNFYSKDDLLRTYCGSLYFAAPELLDAKPYIGPEVDVWSLGVVIYVMVCGRVPFDDVSVPMLHSKIKSGKLEFPSYISEDCCSLIAAMLNVNPRKRCSLEQAAKFPWLKKNSFCLYLPIPLTSIPSTPSIRSHVFKPPFNLKVLQLLHEHGLASIPELKHELYMAYIERKTTSLVCLYLLGVESLAPALRIPTALPPVYSRHQRHHSEILGAMDLTEKITAMQCPP
What are the official names of this protein?
Serine/threonine-protein kinase ppk25.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RPOA_STRT2
Sequence: MIEFEKPIITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLSSLPGAAVTSIKIDGVLHEFDTVPGVREDVMQIILNIKGLAVKSYVEDEKTIELDVQGPAEVTAGDILTDSDIEIVNPDHYLFTIAEGASFQATMTVSTNRGYVPAEENKKDDAPVGTLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIVTNGTIIPEDALGLSARILIEHLNLFTDLTDVAKATDVMKETEKVNDEKLLDRTIEELDLSVRSYNCLKRAGINTVHDLTEKTEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: YOR5_KLEPN
Sequence: MFSTILIVCTGNICRSPIGERYLQQLLPSKNISSAGTQALVDHEADQSAVEVARKNGISLAGHLGRQFTSKLSKEYELILVMEKNHIEQISNIAPEARGKTMLFGHWLEQRDIPDPYRKSEEAFASVFKLIEQSALLWAEKLKA
What are the official names of this protein?
Putative low molecular weight protein-tyrosine-phosphatase, ORF5.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.