PharMolix/UniProtQA huggingface dataset:
Protein: TRT6_ASPTN
Sequence: MLEPVSTAQSLWSFGLWILVILSPVLFFASRELGILNAKKRFAKNGFEEVLAGLRKSDVFGLMTINGPKIVLAPKFAQEIRSNPALSVSAFSSSELHAHIRGFDVFRQGEADDILQDTVRSKITQSIGDLIQPLSEECSLTLKPKWTDSPEWHEVCPHTTILDIIARLSSRAFIGDELCRNPKWLRLTVDFTVDSFRAAEALNWWPYALRPLVARFLPSCLKLHKYIQDADNMMKPVLESRRQAQAKDPQKSYPDTIQWFEETAQGRPYDPVRLQLTLAFASIHTTADLVIQTILDLCSAKNWDELCRSLREEIISSFREEGWRKPLLAKLKIMDSALKESQRLKPVSIVGMGRIAKEAVKLSNNTIIPKGTRLLVSNTAMWDPEIYPDPRTYDPYRFLRLREASENESAGQLVSLSPTHLSFGLGKHACPGRFFAAAEVKIILCHILLKYDIKLADGCKPKPLRAGTNLVADPTAKLLVRRRQEEVAL
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of terretonin, a fungal meroterpenoid that acts as a mycotoxin (PubMed:22549923, PubMed:23116177, PubMed:25671343).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase trt4 (PubMed:22549923, PubMed:23116177).  DMOA is then prenylated into farnesyl-DMOA by the polyprenyl transferase trt2 (PubMed:22549923, PubMed:22782788, PubMed:23116177).  Methylation by the methyltransferase trt5 then leads to farnesyl-DMOA methyl ester which is further subject to epoxidation by the FAD-dependent monooxygenase trt8 to yield epoxyfarnesyl-DMOA methyl ester (PubMed:22549923, PubMed:22782788, PubMed:23116177).  Cyclization of epoxyfarnesyl-DMOA methyl ester by the terpene cyclase trt1 leads to a tetracycle intermediate which is in turn converted to preterretonin (PubMed:22549923, PubMed:22782788, PubMed:23116177).  Dehydrogenase trt9 comes next to transform preterretonin to preterrenoid (PubMed:22549923, PubMed:23116177).  The FAD-dependent monooxygenase trt3 is then required for the C-hydroxylation at C16 of preterrenoid to yield terrenoid (PubMed:22549923, PubMed:23116177).  The cytochrome P450 trt6 catalyzes three successive oxidations to transform terrenoid into an unstable intermediate, which then undergoes the D-ring expansion and unusual rearrangement of the methoxy group to afford the core skeleton of terretonin (PubMed:25671343, PubMed:28759016).  Trt14 catalyzes the D-ring expansion of terretonin involving intramolecular methoxy rearrangement as well as the hydrolysis of the expanded D-ring and the methyl ester moiety (PubMed:25671343, PubMed:28759016).  Finally, the nonheme iron-dependent dioxygenase trt7 accomplishes the last two oxidation reactions steps to complete the biosynthesis of terretonin (PubMed:25671343).  Terretonin C is produced via spontaneous decarboxylation of the terretonin precursor (PubMed:23116177).  Another shunt product of the terretonin biosynthesis is dihydrofarnesyl-DMOA, derived from epoxyfarnesyl-DMOA through hydrolysis of the epoxide (PubMed:22549923, PubMed:22782788, PubMed:23116177).
What are the official names of this protein?
Cytochrome P450 monooxygenase trt6, Terretonin synthesis protein 6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NTF3_LICTR
Sequence: IQSTSMDQGILTEDSMNSFIRTLIQAGIWKNKVPKQTARTKDGMQTTVKKTEAEADAMASKDTRLGFQPVVSVDAELLRQQRRFSSPRVLLSENTPLEPPPLYLTEEPMVLNRTSRRKREGKSHRGEYSVCDSESRWVTDKSSAVDIRGHQVTVLGEIRMGSS
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_CAMVS
Sequence: MAESILDRTINRFWYNLGEDCLSESQFDLMIRLMEESLDGDQIIDLTSLPSDNLQVEQVMTTTEDSISEEESEFLLAIGETSEEESDSGEEPEFEQVRMDRTGGTEIPKEEDGEGPSRYNERKRKTPEDRYFPTQPKTIPGQKQTSMGMLNIDCQTNRRTLIDDWAAEIGLIVKTNREDYLDPETILLLMEHKTSGIAKELIRNTRWNRTTGDIIEQVIDAMYTMFLGLNYSDNKVAEKIDEQEKAKIRMTKLQLCDICYLEEFTCDYEKNMYKTELADFPGYINQYLSKIPIIGEKALTRFRHEANGTSIYSLGFAAKIVKEELSKICDLSKKQKKLKKFNKKCCSIGEASTEYGCKKTSTKKYHKKRYKKKYKAYKPYKKKKKFRSGKYFKPKEKKGSKQKYCPKGKKDCRCWICNIEGHYANECPNRQSSEKAHILQQAEKLGLQPIEEPYEGVQEVFILEYKEEEEETSTEESDGSSTSEDSDSD
What is the function of this protein?
Self assembles to form an icosahedral capsid, about 50 nm in diameter, nm, composed of 420 subunits of the viral capsid protein.  The capsid encapsulates the genomic dsDNA.  Following virus entry into host cell, provides nuclear import of the viral genome.  Virus particles do not enter the nucleus, but dock at the nuclear membrane through the interaction with host importins (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LAMB2_YERPE
Sequence: MKTSLRTLSVALAAALVSPSVLAIEKIDFHGYMRAGVGVSSDGGLAEWQKTMVGRLGNESDTYGEIGLGAEVYKKEDVSFYLDSMVSMLSDGSNDSETTIGDDAQFGLRQLNLQIKGLIPGDKEAVIWGGKRYYQRHDLHIIDTKYWNISGSGAGIENYTVGPGAVSVAWVRGDANDVDTRITGDSDVNINYIDVRYAGFKPWAGSWTEVGIDYAMPNPTKQQKEYGGLYDADNAVMLTGEISQDMFGGYNKLVLQYANKGLAQNMISQGGGWYDMWHKTDEAKGYRVINTGLIPITDKFSFNHVLTWGSANDITEYTDKTNLISLVGRAQYQFTQYVRAIGEVGGFYQKDTYHNGSNYKQGGEKYTIALGLAEGPDFLSRPELRVFASYLNDSENGKPFEDGTSNDTWNFGVQVEAWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin 2, Maltose-inducible porin 2.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: Y1614_BACC4
Sequence: MKVIAVTGYKPFELGIFKNDHPGVECIKKALHRKLLTFVEDGLEWVIISGQLGVELWAAEVVFEMQVEYPDLKLAVFTPFLEQEENWKEDNREYYEFILSQADHVDSITKRKYESPEQFKLKNQFFIEKSDALLAVYDEEKPGSPKYIVESAKKKGEIENYHSYFILFSDLQDIIEEEQWNNAE
What are the official names of this protein?
UPF0398 protein BCB4264_A1614.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: PIN1_MOUSE
Sequence: MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGGSTVGGSSKNGQGEPAKVRCSHLLVKHSQSRRPSSWRQEKITRSKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGPFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
What is the function of this protein?
Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs (PubMed:29686383).  By inducing conformational changes in a subset of phosphorylated proteins, acts as a molecular switch in multiple cellular processes.  Displays a preference for an acidic residue N-terminal to the isomerized proline bond.  Regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity.  Down-regulates kinase activity of BTK.  Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation.  Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation (By similarity).  Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner (PubMed:17828269).  Acts as a regulator of JNK cascade by binding to phosphorylated FBXW7, disrupting FBXW7 dimerization and promoting FBXW7 autoubiquitination and degradation: degradation of FBXW7 leads to subsequent stabilization of JUN (By similarity).  May facilitate the ubiquitination and proteasomal degradation of RBBP8/CtIP through CUL3/KLHL15 E3 ubiquitin-protein ligase complex, hence favors DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR) (By similarity).  Upon IL33-induced lung inflammation, catalyzes cis-trans isomerization of phosphorylated IRAK3/IRAK-M, inducing IRAK3 stabilization, nuclear translocation and expression of pro-inflammatory genes in dendritic cells (PubMed:29686383).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Colocalizes with NEK6 in the nucleus. Mainly localized in the nucleus but phosphorylation at Ser-73 by DAPK1 results in inhibition of its nuclear localization.
Protein: ARP2_MOUSE
Sequence: MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR
What is the function of this protein?
ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.  Seems to contact the pointed end of the daughter actin filament.  In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation.  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
What are the official names of this protein?
Actin-related protein 2, Actin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Protein: RSMA_DESVV
Sequence: MPPRAKKSLGQNFLKDRNIAARIAAQLHIGPDDWVIEIGPGPGALTRHIHAAGPARLFLLEKDHHWAREHHLHPLAGTPEAQVVLTDALLFPWERLDAAHPWKVIGNLPYNVASPLMWDICSRAPGLVRASFMIQKEVGERIVAAPGSRQYGALSVWLQCFTKPEWCFVVPPHVFTPRPKVDSAVLAFTPRTDRPDAVQSKRLAHVLRLCFQQRRKQLQGILRPHVGGDASALLAELGIDPAARPETLSPERFIALGEAVAMSAIA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGR2B_XENLA
Sequence: MESVLKSLFVLLVATSFTLAKEIPAKVSKPQTLSRGWGDNLEWVQTYEEGLYKAKAENKPLMLINHRNDCPHSLALKKAFAEHQGIQKLAEEFILLNVVYDPTDKNLQLDGQYVPKIIFVDPSLVVRADLPGKYSNHQYTYEPADIDHLFENMKKALVLLKTEL
What are the official names of this protein?
Anterior gradient protein 2-B.
What is the protein family that this protein belongs to?
Belongs to the AGR family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum.
Protein: CB13_SOLLC
Sequence: MATQALISSSSISTSAEAARQIIGSRISQSVTRKASFVVRAASTPPVKQGANRQLWFASKQSLSYLDGRLPGDFGFDPLGLSDPEGTGGFIEPKWLAYGEVINGRFAMLGAAGAIAPEILGKAGLIPQETALAWFQTGVIPPAGTYNYWADNYTLFVLEMALMGFAEHRRFQDWAKPGSMGKQYFLGLEKGLGGSGDPAYPGGPLFNPLGFGKDEKSMKELKLKEIKNGRLAMLAILGYFIQALVTGVGPYQNLLDHLADPVNNNVLTSLKFH
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein 8, chloroplastic, LHCI type III CAB-8.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: POMT1_RAT
Sequence: MGNRSMGREDTLGVLPSLLFCKMLRFLKRPLVVTIDINLNLVALTVLGLLTRLWQLSYPRAVVFDEVYYGQYISFYMKRVFFLDDSGPPFGHMLLALGGWLGGFDGNFLWNRIGAEYSSNVPVWSLRLLPALAGALSVPMAYQIVLELHFSHCTAMGAALLMLIENALITQSRLMLLESILIFFNLLAVLSYLKFFNSQTHSPFSVHWWLWLMLTGVSCSCAVGIKYMGIFTYLLVLSIAAVHAWHLIGDQTLSNICVLSHLLARAVALLVVPVFLYLLFFYVHLMLLYRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGSQVTLKSVSGKPLPCWLHSHKNTYPMIYENGRGSSHQQQVTCYPFKDINNWWIVKDPGRHQLVVNNPPRPVRHGDIVQLVHGMTTRLLNTHDVAAPLSPHSQEVSCYIDYNISMPAQNLWKLDIVNRESNQDTWKTILSEVRFVHVNTSAILKLSGAHLPDWGFRQLEVVGEKLSLGPHESMVWNVEEHRYGRGHEQKERELELHSPTQHDISRNLSFMARFSELQWKMLTLKNEDLEHQYSSTPLEWLTLDTNIAYWLHPRTSAQIHLLGNIVIWTSASLATVAYTLLFFWYLLRRRRNICDLPEDAWSHWVLAGALCIGGWALNYLPFFLMERMLFLYHYLPALTFQILLLPIVMQHASDHLCRSQLQRNVFSALVVAWYSSACHVSNMLRPLTYGDTSLSPGELRALRWKDSWDILIRKY
What is the function of this protein?
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.  Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient.  Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins.
What are the official names of this protein?
Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: 5HT1F_RAT
Sequence: MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINCLVITAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQGLCDLWLSVDIICCTCSILHLSAIALDRYRAITDAVEYARKRTPRHAGITITTVWVISVFISVPPLFWRHQGNSRDDQCIIKHDHIVSTIYSTFGAFYIPLVLILILYYKIYRAARTLYHKRQASRMIKEELNGQVLLESGEKSIKLVSTSYMLEKSLSDPSTDFDRIHSTVKSPRSELKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNICEKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRN
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various alkaloids and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity.
What are the official names of this protein?
5-hydroxytryptamine receptor 1F, 5-HT-1F, 5-HT1F, Serotonin receptor 1F.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHID1_XENTR
Sequence: MRLLSTLLFLVAATCPLIHATLSKTDSKKAASKAPETKTRLSDTLVQTRGLVSTDVKAKDIVLEHRSYCAKKLKERHVSADVLGYVTPWNGHGYDIAKTFAAKFTLISPVWLQIKRKGKEAYHITGLHDVDQGWIKDIRKTSKSTQIVPRILFDGWSYQDFESVFSSEDEIEELAGAMVQTAKDERFDGFVVEVWSQLGGQKRQELVHLLTHIGEALRLAKLRFILVIPPALAPGTDHLGMFGRKEFDQLAPVVDSFSLMTYDYSSPQRPGPNSPITWVQACIQLLDPESKWRKKILLGLHFYGMDYSALGASGEPILGNRYIEILKEHKPKLLWDQQIAEHYLEYKKNKGGKHAVFFPTLKSIQVRLDLAEELGTGISIWELGQGLDYFYDLL
What are the official names of this protein?
Chitinase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Secreted. Lysosome.
Protein: PRL1_LEIMA
Sequence: MEVNATLIDCCDPQKPSRVLFHFLILDAPSPSNLPTYIKELQHRGVRHLVRVCGPTYDATLVKSRGIDVHSWPFDDGAPPTRAVLDSWLKLLDTELARQQEDPSVPPPTIGVHCVAGLGRAPILVALALVEYGNVSALDAIALIREKRKGAINQTQMHWITKYKRRHQGAGCVIM
What is the function of this protein?
Has protein tyrosine phosphatase activity and may act as a virulence factor to support intracellular survival in host macrophages.
What are the official names of this protein?
Protein tyrosine phosphatase PRL-1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion matrix, kinetoplast. Secreted, extracellular exosome. Secreted. Note=Enriched around the kinetoplast.
Protein: TYDP2_HUMAN
Sequence: MELGSCLEGGREAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVEESALERRPETISEPKTYVDLTNEETTDSTTSKISPSEDTQQENGSMFSLITWNIDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFTAIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNVSGNELCLMTSHLESTRGHAAERMNQLKMVLKKMQEAPESATVIFAGDTNLRDREVTRCGGLPNNIVDVWEFLGKPKHCQYTWDTQMNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLLGLEKLDCGRFPSDHWGLLCNLDIIL
What is the function of this protein?
(Microbial infection) Also acts as a 5'-tyrosyl-RNA phosphodiesterase following picornavirus infection: its activity is hijacked by picornavirus and acts by specifically cleaving the protein-RNA covalent linkage generated during the viral genomic RNA replication steps of a picornavirus infection, without impairing the integrity of viral RNA.
What are the official names of this protein?
Tyrosyl-DNA phosphodiesterase 2, Tyr-DNA phosphodiesterase 2, hTDP2, 5'-tyrosyl-DNA phosphodiesterase, 5'-Tyr-DNA phosphodiesterase, ETS1-associated protein 2, ETS1-associated protein II, EAPII, TRAF and TNF receptor-associated protein, Tyrosyl-RNA phosphodiesterase, VPg unlinkase.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Nucleus, nucleolus. Cytoplasm. Note=Localizes to nucleolar cavities following stress; localization to nucleolus is dependent on PML protein. SUBCELLULAR LOCATION: Cytoplasm. Note=(Microbial infection) In case of infection by picornavirus, relocalizes to cytoplasmic sites distinct from those containing viral proteins associated with RNA replication or encapsidation.
Protein: MURE_CHLMU
Sequence: MHLDQLLRDIPAKIYGKVESIPVRNLTRDSRCTGVGDIFIARQGQMCNGNDYSGQAVENGAIAILSSLYNPFLSVVQIVTEDLTALEACLAARFYNDPSKRLDVIGVTGTNGKTTVSALARELMEYKGRCTGLVGTIEHILGEHRIIDSFTTPDAILLQKYFAEMVKQNLSSAVVEVSSIGLALGRVRETEFLAGVLTNVSLDHLDFHGSFEEYVVAKKQLFVSLPEHGVAVVNSDCEYAQSFLEISPARGVSYAVHQEADYRAVNLKFSSLGSTFDILYQGNVFSCETSLVGEHNVYNVLAALSVVHQILGGDFAELVHYVRYLSAPKGRLEPVLSGPCPIYIDYAHTPDALDNVCKILSQLLPADGRLIIVFGCGGDRDHSKRPIMAKVAETYGFSVVTSDNPRTEDPDQIIADICSGFSTDRYVIESDRRLAIVKAISMALDKDIVLVAGKGHEVYQIFKHQTIVFDDREVVCEALASIY
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFE_ECO45
Sequence: MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDKSPQNSIQGCQSQVWIVMRQNAQGIIELHGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_ALKOO
Sequence: MEAKLKALEEKAKLEISQADSTAVLEQARVHYLGKKGELTEILRGMGALSAEERPLVGKIANLVRENIEAALEEAKATVKSKELEKKLMAETIDVTMPGKAIKLGKKHPLTQAMDDLKEIFISMGFKVVEGPEIETVYYNFDGLNAAKNHPSRDMSDTFYFNENTILRTQTSPVQVRTMEKSKPPIRIVSLGRCFRNDTPDATHSPMFHQIEGLVVDEGITMGDLKGTLEVFAKNFFGEDTKIKFRPHNFPFTEPSAEVDATCFKCGGKGCGVCKGNGWIEVLGAGMVHPNVLRNCGIDPEIYSGFAFGMGIDRLTMQKYGIDDIRLLFENDMRFIDQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_XANAC
Sequence: MSALVGNARTSDPAAFGRVAVLLGGTSSEREVSLNSGGNVLDALRARGVDAQPVDGIPALAKALVAQQFDRVFNVLHGHNGGGEDGIVQGLMEAFGVPYTGSDVLGSALSMDKIRTKQVWLSLGLSTPRYARLAAGASAEDIHAAARQIGLPIIVKPANEGSSVGVSRVFDQAQLEEAVTLAARYDGALLMEQLIEGDELTVAVLGDTALPSIRIVPKGQWYDYNAKYIADDTQYLCPGLEGEAEAQIRQLALDAFRAAGCRGWGRVDVMRDGSSGQLYLLEVNTAPGMTSHSLVPKAARQLGIDFETLVWRVLEQTL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB_SYNS9
Sequence: MTKESADKQQSTAENIAVSMQNVTISYGKSAAVKDVFCEISTGKVTAFIGPSGCGKSTLLRSINRMNDLIEGCTLKGRVLFDGVDLYDAAVDPVEVRRRIGMVFQQPNPFPKSIYENVAFGARINGYTGNMDELVERSLRQAAVWDECKDKLKDSGCSLSGGQQQRLCIARTIATQPEVILMDEPCSALDPISTLKIEETMHELKKSFTIVIVTHNMQQAVRVSDETAFFNAETVENRSGKVGYLVEFNDTQSIFNSPQQQATQDYVSGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BOP1_DROWI
Sequence: MAKKQDRKRKVKDEATNDGASGSDQSDNAEEEEDLLQTVKEPGEDSTDDEGIDQEYQSDSSEDLEFESDEEGNYVGRKGGQQESSDEEEVDEEEEDDDDDDDEEEGGKVEDKPTTSSKAETNNEVAPLPALPARDPSKQEYEDSDTSDEEDIRNTVGNIPMHWYDEYKHIGYDWDGNKIIKPIKGDQIDDFLRKIEDPDFWRTVKDPQTGQEVVLSDADIALIKRINSARIPNAEHEEYEPWIEWFTSEVEKMPIKNVPDHKRSFLPSVSEKKRVSRMVHALKMGWMKTTEEVEREKQQKRGPKFYMLWETDTGREQMRRIHDPVSAPKRDLPGHAESYNPPPEYLFDEKETKQWLKLKDEPHKRKLHFMPQKFKSLREVPAYSRYLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPRDLQPFPTVESLVYRGHTDLVRSVSVEPKGEYMVSGSDDKTVKIWEIATGRCIRTIETEDVVRCVAWCPNAKLSIIAVATGSRLLLVNPKVGDKLLIKKTDDLLAEEPSNQDIIDNERIKTAVQWSTAEAAEQEKGVRVIINHFKPIRQVTWHGRGDYLATVMPEGANRSALIHQLSKRRSQIPFSKSKGLIQCVLFHPVKPCFFVATQHNIRIYDLVKQELIKKLLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDLSTKPYQTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVSHGMVYNDLLQNPLIVPLKKLQTHEKRDDFGVLDVCWHPVQPWVFSTGADCTIRLYT
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: RL32_MYCTA
Sequence: MAVPKRRKSRSNTRSRRSQWKAAKTELVGVTVAGHAHKVPRRLLKAARLGLIDFDKR
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.