PharMolix/UniProtQA huggingface dataset:
Protein: DNAA_BUCA5
Sequence: MSLCLWKQCLDRLQDELPNTEFSMWIRSLKAKLNNNILEIYAPNKFVLEWVKDKYLNHLKKILQDYCGTNSPLIKFEIYQIYKENKLKKNIENNNNNKNEKLIWSNIPKFKNLSYRSNINKRYNFQNFVEGKSNQLARSAAFQAARNPGNSYNPLFLYGATGLGKTHLLHAIGNEILSYKYDIKIIFMNSECFVQDMVKALKNNAIEKFKLYYRSVDALLIDDIQFFAHKERSQEEFFHTFNTLIEGNQQIILTSDRYPKEINGVEDRLKSRFSWGLTIAIDPPEIETRVAILIKKADQNNVILSNEVAFFIAKHLRSNVRELEGALNRVILNSRFTHRAITVDFAREALQDILAVQEKIITIDNIQKTVAKYYKIKVSDLLSKKRSRSIARPRQMAMAMAKKLTNHSLPEIGEAFSGRDHTTVLHACCKIEQLRKENHDIKKDFLNLIRTLSK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRNQL_STAEQ
Sequence: MNKNTWIIGFTLFAMFFGAGNLIFPTQLGLESGHFFWPAILAFALTGIGLPLLGVVVGALDKHGYIGSFNKISPRFSLIFLIIIYLTIGPLFAIPRTASTSFEMTVTPIAHNSGNLALFIFTVIYFLIVLYLCLNPNKMIDRIGSLLTPLLLITIVAMIIKGFVDFGGHSSNYGMTNAYHSNLSGFSQGFTQGYLTMDAIASIAFSMIVVNAIKTTGIQHADKIFKQTIIAGLIAAIALVFIYISLGYIGNHINIPSDTLKELKAKDQNIGTYLLTTMATKGFGTFGKYLLGIIVSLACLTTACGLIVSVSEYFHRIIPKIPYKVFVVFFILVSFILANQGLNSVIKMSVPVLSVIYPVAITVILLILIARFIPTKRIAQQIPLIIVAIESILSLITTQGWIRISLIDSLPLKEYSLEWFPIAVVATLVGYMISYFVKQSNIVYQKE
What is the function of this protein?
Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine), which is coupled to a proton motive force.
What are the official names of this protein?
Putative branched-chain amino acid carrier protein SERP0977.
What is the protein family that this protein belongs to?
Belongs to the branched chain amino acid transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPX_STRPN
Sequence: MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVDGTDKPILETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: AIMP1_HUMAN
Sequence: MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
What is the function of this protein?
Non-catalytic component of the multisynthase complex.  Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase (PubMed:10358004).  Binds tRNA.  Possesses inflammatory cytokine activity (PubMed:11306575).  Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation (By similarity).  Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels (By similarity).  Promotes dermal fibroblast proliferation and wound repair (PubMed:16472771).  Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum (By similarity).  Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations (PubMed:12237313).  Induces maturation of dendritic cells and monocyte cell adhesion (PubMed:11818442).  Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (PubMed:19362550).
What are the official names of this protein?
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43.
Protein: FTHS_SYNFM
Sequence: MPYDATKMMDWQISEEAEKDMPSPWQWQEKLGLLKEEILPMGRLCKLDFLKIMNRLKDKPDGKYIEVTAITPTPLGEGKSTTSVGLMEGLGKRGVNVGGCLRQPSGGPTMNIKGTAAGGGNALLIPMTEFSMGLTGDINDIMNAHNLAMVALTARMQHERNYTDEQLDRLTKMRRLHIDPTRVEMGWIMDFCAQALRNIIIGIGGRQDGYMMQSKFGIAVSSELMAILSIVKDLPDLRKRLNEITVAFDRRGNPVTTGDLEVGGAMTAFMRNTINPTLMCTAEYQPCMVHAGPFANIAVGQSSIIADRIGLKMFDYHVTESGFAADIGFEKFWNVKCRYSGLKPHVSVLTTTIRALKMHGGGPKVVAGLAMPEEYTKENLKLLEKGIVNMVHHINTIRKSGMNPVVCINAFHTDTKDEIALVRKHAEAAGARCALSEHWAKGGEGALEFADAVIDACKQESQFKFLYPLEMKLRDRVSTVAREVYGADGVSWTPDAEAKAKMLENDPKYDDYATMMVKTHLSLTHDPSVKGVPKGWVLPIRDVLIYSGAKFLCPCAGTISLMPGTSSNPAFRRIDVDVNTGKVKGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RAD14_YEAST
Sequence: MTPEQKAKLEANRKLAIERLRKRGILSSDQLNRIESRNEPLKTRPLAVTSGSNRDDNAAAAVHVPNHNGQPSALANTNTNTTSLYGSGVVDGSKRDASVLDKRPTDRIRPSIRKQDYIEYDFATMQNLNGGYINPKDKLPNSDFTDDQEFESEFGSKKQKTLQDWKKEQLERKMLYENAPPPEHISKAPKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYFLTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGLDEEWQRREEGKAHRREKKYEKKIKEMRLKTRAQEYTNRLREKKHGKAHIHHFSDPVDGGIDEDGYQIQRRRCTDCGLETEEIDI
What is the function of this protein?
Involved in nucleotide excision repair.  Binds specifically to damaged DNA.  Required for the incision step.
What are the official names of this protein?
DNA repair protein RAD14.
What is the protein family that this protein belongs to?
Belongs to the XPA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEXA_LIMF3
Sequence: MPRNSTNKQMAVLSFIHKQVDAHGYPPTVREICGAVGLSSTSTVHGHINRLIKKGYLKKDPSKPRALEITPAGLEVLGITPKQTQIPLLGVVAAGEPILAVQDATDFFPIPPSIPDHDDLFMLTIQGTSMINIGILNGDKVIVRRQETANNGDIVIAMTSDNEATCKRFFKEQGHIRLQPENDTLAPIILDDVTILGKVVGLFRDDIF
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SYA_ALBFT
Sequence: MNSTVAPASVADIRKIFLDFFASKGHTVVPSSPLVPGNDPTLMFTNSGMVQFKDVFLGTDKRSYVRAASVQACLRAGGKHNDLENVGYTARHHTFFEMLGNWSFGDYFKRDSLKWGWELLTKVYKLPADKLWATVYIDDDEAYNIWTQEIGLPPERVVRIGDNKGAKYASDNFWMMADTGPCGPCSEIFYDHGPAIAGGPPGSPEQDGDRYIEIWNHVFMQYDMQPDGSVKPLPAPCVDTGMGLERLAAILQHVHSNYEIDIFDALIKAAARETGCTDLGNKSLRVIADHIRATAFLVSDGVLPSNEGRGYVQRRIIRRAIRHGYKLGQKAPFFYKLVPDLVTLMGEAYPGLATQAERIAQVLQAEEERFFETLANGMQILDETLTGDAKVLPGDVAFKLHDTFGFPLDLSADVCRERGVEVDEAGFHAAMEKQKAQGRAAGKFRMDRALEYSGDGNDFVGYERLTEVTKIVALYADSTPVSELKAGQAGVVVLAATPFYGESGGQVGDQGAIFSDGAMFDVADTQKIKADVFGHHGVLKSGALKIGDVVTAHVNASLRAATQRNHSATHLMHKALREVLGAHVQQKGSLVNAERTRFDFAHNAPVTDEQIREVEARVNSEILSNAATQSRVMDIDAAQETGAMMLFGEKYGESVRVLDIGASRELCGGTHVARTGDIGLFKVVAESGVASGVRRIEAVTGQNALSYLQDLEDTVTQVAGTLKAPVVEINERVAGVLDHLKSLEKEIAALKGKLASAQGDELVTQAVDVKGIKVLVAMLEGADTKTLRDTMDKLKDKLKSAVIVLAAVEGDKVQIAAGVTSNSVGKVKAGELVNFVASQVGGKGGGKPDMAMAGGTEPAKLPAALASVMAWVSAKL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_ACIAD
Sequence: MFSILLRLSLVTKIFIAIILGFVVAFLFPNMTPYFSIFGEIFIKALKAVAPILVFVLVISSIANFNVEQSAKNFKPILFLYIVSMLFAAFSAVIADLLFPTTLVLASSADQAFQPPGSLNDVLKNLILSFVSNPVVALSEANFIGILAWAIILGTAFRHSTQATKTVLQDCADAIGKVIHLVISFAPIGIFGLVAVTFAHSGIETLKSYSHLLLVLLGTMFFMALIVNPIMVACVIKKNPYPLVFKCLRESGITAFFTRSSAANIPVNLDLARRCGVDESTSNVIIPLGSTVNMCGAAITITVLTLATVNTLGISVDIWTMLILCVVASISACGASGVAGGSLLLVPVACSLFGISSDIAMQVVAIGMVISVLQDSTETALNSSTDVLFVIAVDQASKT
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOB_AGRFC
Sequence: MGMSQNNSTLVAPQPKGIIDPATGKPVGSNDAYFTEINDELADKGFLVTSTDELITWARTGSLMWMQFGLACCAVEGLMQASGPRYDMERFGVAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYAVVRGCDRVVPVDIYVPGCPPTAEALLYGVLLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NCAP_I75A2
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRRDGKWMRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMVKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVVPRGQLSTRGVQIASNENMETMDSSTLELRSRYRAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PRDX6_RAT
Sequence: MPGGLLLGDEAPNFEANTTIGHIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIALSIDSVEDHFAWSKDINAYNGAAPTEKLPFPIIDDKDRDLAILLGMLDPAEKDEKGMPVTARVVFIFGPDKKLKLSILYPATTGRNFDEILRVVDSLQLTASNPVATPVDWKKGESVMVLPTLPEEEAKQLFPKGVFTKELPSGKKYLRYTPQP
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (PubMed:15004285).  Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides (By similarity).  Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity) (PubMed:8999971, PubMed:15004285, PubMed:17652308).  These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH (By similarity).  Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis (By similarity).  Exhibits acyl-CoA-dependent lysophospholipid acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (PubMed:26830860).  Shows a clear preference for LPC as the lysophospholipid and for palmitoyl CoA as the fatty acyl substrate (By similarity).
What are the official names of this protein?
Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, Acidic calcium-independent phospholipase A2, aiPLA2, Antioxidant protein 2, Glutathione-dependent peroxiredoxin, Lysophosphatidylcholine acyltransferase 5, LPC acyltransferase 5, LPCAT-5, Lyso-PC acyltransferase 5, Non-selenium glutathione peroxidase, NSGPx, Thiol-specific antioxidant protein.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Lysosome. Note=Also found in lung secretory organelles (lamellar bodies).
Protein: ELF2_MOUSE
Sequence: MASAVVDSGGSALELPSDGGENQEGGDTGPDCPAVIVEPVPSARLEQGYAAQVLVYDDETYMMQDVAEEQEVETENSETVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEVFVPPCISTPEFIHAAMRPDVITETVVEVSTEESEPMDASPIPTSPDSHEPMKKKKVGRKPKTQQSPVSNGSPELGIKKKAREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVIDDDKSETCPEDLAAAADDKSLERVSLSAESLLKAATAVRGGKNSSPLNCSRAEKGVARVVNITSPTHDGSSRSPTTTAPVSAAAAPRTVRVAMQVPVVMTSLGQKISAVAVQSVNAGTGSPLITSTSPASASSPKVVIQTVPTVMPASTENGDRITMQPAKIITIPATQLAQCQLQAKSNLTGSGSINIVGTPLAVRALTPVSIAHGTPVMRLSVPAQQASGQTPPRVISALLKGPEGKSEAKKQEHDVKTLQLVEEKGADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK
What is the function of this protein?
Probably transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.
What are the official names of this protein?
ETS-related transcription factor Elf-2, E74-like factor 2, New ETS-related factor.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAA_SPIKU
Sequence: MKTTNKIIILDFGSQYTQLIARRIRDLEVYCEVWPYNTALEKIKTTSMKGIILSGGPASVYEEDAFLIDKQLFELKVPVLGICYGMQIISHLHEGTVQRATKQEFGFSELIIDNQEDLFANIPVKSQVWMSHADYIEGMPTNFIQIAHSENSISAIKHSEKKIYGLQFHPEVTHTLIGQQLLSNFVFNICGCQPKWKITEFISAAITEIKNKVGTDNVVLALSGGVDSSVCAVLLHKAIGKQLTCIFVDTGLLRQNSGWNDLQKFQEKFKLNIIKINAQERFLTALKGVTNPEEKRKIIGNLFIEIFNEEAIKIQNVKWLGQGTIYPDVIESVSVKGPSATIKSHHNVGGLPKDLPFQLIEPLRELFKDEVRRTGEALGIDFKFVYKHPFPGPGLAVRIIGEITAEKIALLQAADQIFIDELYQANLYDQVAQAFVVLLPVQSVGVMGDVRTYGYTAVVRSVDTTDFMTANWSRLPFELLEKVSARIVSEVHGINRITYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL1_SALTO
Sequence: MQHSKNYRKAAAAIDRSKLYTPAEAVKLAKETTSVKFDATVEVAMRLGVDPRKADQMVRGTVNLPHGTGKTARVIVFAAGAKAEEAVAAGADEVGTDELVARIQGGWLDFDAAIATPDQMAKIGRIARILGPRGLMPNPKTGTVTMNVTKAVADIKGGKIAFRVDKHSNLHLIIGKASFSESQLVDNYAAVLDEILRAKPSAAKGKYLRKVTLTTTMGPGVPIDPNVVKNLRENSAEG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: FLBD_CAUVC
Sequence: MRLLVVGKLNGQLSVAVKMAMNAGAKVSHVETTEQATNALRAGQGADLLMVDYVLDIAGLIAANEAERMRVPVVACGVDADPMRAANAIKAGAKEFIPLPPDAELIAAVLAAVTDDEKPMVVRDPAMEQVIKLADQVAPSEASILITGESGSGKEVMARYVHGKSRRAKAPFISVNCAAIPENLLESELFGHEKGAFTGAMARRIGKFEEADGGTLLLDEISEMDVRLQAKLLRAIQEREIDRVGGSKPVKVNIRILATSNRDLAQAVKDGTFREDLLYRLNVVNLRLPPLRERPADVISLCEFFVKKYSAANGIEEKPISAEAKRRLIAHRWPGNVRELENAMHRAVLLSAGPEIEEFAIRLPDGQPMAPAPDVAVARGAQMAADAASRAFVGSTVAEVEQQLIIDTLEHCLGNRTHAANILGISIRTLRNKLKEYSDAGVQVPPPQGGVGAAA
What is the function of this protein?
Activation of sigma-54-dependent flagellar gene promoters and strong negative autoregulatory effects on its own promoter.  The synthesis and function of FlbD in C. crescentus is controlled by an internal cell-cycle clock.
What are the official names of this protein?
Transcriptional regulatory protein FlbD.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRLB_ACHLY
Sequence: MKKISKAGLGLALVCALATIGGNAARRATAQRRGSGVFYDEMFDFDIDAHLAKHAPHLHKHSEEISHWAGYSGISRSVDRADGAAERAVTPSARRIVRSASWRAPTASARRPARSRWRCASRCTSAIPTRQGAGDAGPRQSAAGAVRAFRRQRAGGRAARRRRVPAGLRPPVQRTAPGQGGFGPLRQGRPGRAAVSPNGLLQFPFPRGASWHVGGAHTNTGSGNYPMSSLDMSRGGGWGSNQNGNWVSASAAGSFKRHSSCFAEIVHTGGWSTTYYHLMNIQYNTGANVSMNTAIANPANTQAQALCNGGQSTGPHEHWSLKQNGSFYHLNGTYLSGYRITATGSSYDTNCSRFYLTKNGQNYCYGYYVNPGPN
What are the official names of this protein?
Beta-lytic metalloendopeptidase, Beta-lytic protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M23A family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACH91_ONCMY
Sequence: MKTVVLLTWISCWIDVCTSAQGRYAQKLLNDLMENYSSALRPVEDTDKTLNVTLQITLSQIKDMDERNQVLTTYLWIRQTWFDAYLKWDKEEYDGLEVIRIPSNLVWRPDIVLYNKADEEASGPADTNVVLRYNGEITWDMPAITKSSCVVDVSYFPFDWQWCNLTFGSWTYNGNQVDIAMGMDSGDLSDFVENVEWECHGMPAVRNVIMYGCCSDPYPDITYTLHLKRRSLFYIFNLLLPCFLISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMPPSESVPYIGKYYIATMTMITASTSLTIFIMNIHFCGAEAKPVPHWAKVLIIDYMSKILFVYEVGENCTTPESERTPLYSEEPMSGNSALARNHYHDDLYHDGGCYQDDCHRLRPYQYGNGHLQNHHSTHQNHLDNCRYANGGHRDDHYSNRSNQNHHSNRSQTSKGEGGEEKREPLRHYHHIGREELDYQAPPPGNLQNGGLNEPLPYPKEKHLNPASAPACSCPCPHHKQVVYNIQYIANCFREQRATCAKGAEWKKVAKVMDRFFMWIFFIMVFLMSILIIGKAT
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-9-I, Nicotinic acetylcholine receptor subunit alpha-9-I, NACHR alpha-9-I.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: O164_CONLT
Sequence: MKLTCVPIVAMLFLMACQLITADYSREKHGYSAEKSSDKIQDSFYSKLTKRCTDEGGDCDPGNHNCCRGSCLVLQHKAVCGILYTMVSR
What are the official names of this protein?
Conotoxin Lt6.4, Lt6d.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPE_BURO0
Sequence: MTDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARVTDVPGVPEESDLVVRAANLLKAHTGTAHGVDVEIDKILPMGAGLGGGSSDAATTLLALNRLWQLDLPRAELQSLAVKLGADVPFFIFGKNAFAEGIGEELAEVELPTRWFLVVTPRVHVPTAEIFSDELLTRDTKPVTIADFLAQQTSDAEWPDSFGRNDMQEVVTRKYAEVAQVVKWLYDVTPARMTGSGASVFAAFHSKHEAEAAKAKLPASWNGAVAESLNEHPLFAFAS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: NRDR_CUPMC
Sequence: MKCPFCGHSSTQVLDSRVSEDGDTVRRRRRCEACDRRFTTYERIELFFPAIVKKNGSRVDYARAKLKDSMRLALRKRPVSAEAIDEAITRIEEKLLALGEKEIPSSQVGELVMRELRKLDKIAYIRFASVYRSFEDVSEFREMLDEFSSSTPRKG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PRMA_SALTI
Sequence: MPWIQLKLNTTGANAEELSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMKDVVAILEQHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDIPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEAMKADVVVANILAGPLRELAPLISVLPVEGGLLGLSGILASQAESVCDAYAELFTLDPVVEKEEWCRITGRKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FER_COLES
Sequence: ATYKVKLVTPSGQQEFQCPDDVYILDQAEEVGIDLPYSCRAGSCSSCAGKVKVGDVDQSDGSFLDDEQIGEGWVLTCVAYPVSDGTIETHKEEELTA
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1054_STAA8
Sequence: MTKYTFKPKDFKAFNVEGLDARMEALNEYIRPQLRELGEYFSDFFTSQTGETFYPHVAKHARRSVNPPKDTWVAFATNKRGYKMLPHFQIGMFEDQLFVMFGIMHEAKDKATRAKVFERKFKAIQQLPDDYRVCLDHMKPDKPFIKDLTDDDLIEAIQRAINVKKGEFFIARAITPQDKRLKSDKAFIAFLEETFDQFLPFYSA
What are the official names of this protein?
UPF0637 protein SAOUHSC_01054.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: DUS3_NEOFI
Sequence: MEPTTQTEPMAVTPKHELENGAAVAANNEEHPSKKQRLESVSITEQEVSDGAPKRMKGVAPIKAEFLVQKSARSQPVEESVVSLSADDAAEAAHYQEREGEQKGKKRASGQNKGRDFGRSEDAKGLCPSRAFSPEFSPKECKFGEKCRFEHDVRTYLKEHKREDLTTFGGICPIWDAKGRCPYGFKCRLVRSHMTERDTSDGRKELILLEDEERKKTARPVVPYASEDGLVNIVSNEDKIAVARRKTTTPRSDAYLTWLDKTSKALEKNLHGRHLEEGGADKGAGAQTKDQVEENRAAYVEPPFLPSEKRRIYFGPETPALAPLTTQGNLPFRRLCIDHGCQFTYSEMAMGMSLIQGQKSEWALMKAHESEALPPTISSTADVVQGYDNSKDLKFGAQIAGNKPWHAIKATELLGRLTPNLRVIDLNCGCPIDQVFREGAGSALLDHPSKLEKMLRGMNAVSEMIPITVKIRTGTRDNSPNATKLIERLVLGGHESSMLNIGPPGVAAITLHGRSRQQRYTKSADWSYIAECAALIKRLNEKKDDVTDTVREPDERMLPNGGKVFFLGNGDCYSHHDYDDHINNAGVDAVMVGRGAIIKPWVFEEIQAGQYLDKSATERLAMVEKYAKYGLDTWGSDEHGVGTTRRFMLEWLSFTYRYVPIGLLEYLPPHIQDRPPAWRGRNELETLLGSPNYKDWIKITEMFLGPAHKDFKFEPKHKSNAYEPQG
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase dus3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.