PharMolix/UniProtQA huggingface dataset:
Protein: SPSA_SPIOL
Sequence: MAGNDWINSYLEAILDVGGQGIDASTGKTSTAPPSLLLRERGHFSPSRYFVEEVISGFDETDLHRSWVRAASTRSPQERNTRLENLCWRIWNLARKKKQIEGEEAQRLAKRHVERERGRREATADMSEDLSEGERGDTVADMLFASESTKGRMRRISSVEMMDNWANTFKEKKLYVVLISLHGLIRGENMELGRDSDTGGQVKYVVELARALGSMPGVYRVDLLTRQVSAPGVDWSYGEPTEMLSSRNSENSTEQLGESSGAYIIRIPFGPKDKYVAKELLWPYIPEFVDGALSHIKQMSKVLGEQIGGGLPVWPASVHGHYADAGDSAALLSGALNVPMVFTGHSLGRDKLDQLLKQGRLSREEVDATYKIMRRIEAEELCLDASEIVITSTRQEIEEQWQLYHGFDLVLERKLRARMRRGVSCHGRFMPRMAKIPPGMEFNHIAPEDADMDTDIDGHKESNANPDPVIWSEIMRFFSNGRKPMILALARPDPKKNLTTLVKAFGECRPLRELANLTLIIGNRDDIDEMSTTSSSVLISILKLIDKYDLYGQVAYPKHHKQSDVPDIYRLAAKTKGVFINPAFIEPFGLTLIEAAAYGLPIVATKNGGPVDIIGVLDNGLLIDPHDQKSIADALLKLVADKHLWTKCRQNGLKNIHLFSWPEHCKNYLSRIASCKPRQPNWQRIDEGSENSDTDSAGDSLRDIQDISLNLKLSLDAERTEGGNSFDDSLDSEEANAKRKIENAVAKLSKSMDKAQVDVGNLKFPAIRRRKCIFVIALDCDVTSDLLQVIKTVISIVGEQRPTGSIGFILSTSMTLSEVDSLLDSGGLRPADFDAFICNSGSELYYPSTDYSESPFVLDQDYYSHIDYRWGGEGLWKTLVKWAASVNEKKGENAPNIVIADETSSTTHCYAFKVNDFTLAPPAKELRKMMRIQALRCHAIYCQNGTRLNVIPVLASRSQALRYLFMRWGVELSNFVVFVGESGDTDYEGLLGGVHKTVILKGIGSNTSNFHATRAYPMEHVMPVDSPNMFQTGGCNIDDISDALSKIGCLKAQKSL
What is the function of this protein?
Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate.  Involved in the regulation of carbon partitioning in the leaves of plants.  May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf.  Plays a role for sucrose availability that is essential for plant growth and fiber elongation.
What are the official names of this protein?
Sucrose-phosphate synthase, UDP-glucose-fructose-phosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family.
Protein: ILVC_THEP3
Sequence: MAKMYYDKDADLNLLKNKKIAIIGFGSQGHAHALNLKDSGLDVVVGLYEGSKSKERAEKEGLRVYTVEEAAKVADIIMILIPDEKQAKVYKESIEKNLTEGKALAFAHGFNIHFKQIVPPKNVDVFMVAPKGPGHLVRRVYQEGKGVPNLVAVYQDYTGKAFDLALAYAKGIGGTRAGVIETTFKEETETDLFGEQAVLCGGVTELMKAGFETLVEAGYQPEIAYFECVHEMKLIVDLIYEGGFSYMRYSISDTAEFGDYMTGKRIITEETRKEMKKVLSEIQSGKFAKEWLLENQVGRPQYNAIKDKEANHLIEKVGKGLREMMAWIKKE
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: 092R_FRG3G
Sequence: MSLHLTLVLSGKNLKIVVESINVVTARSERSSLLDCKRCCKRPNIPHTETVDFVWGFNVETRLIAAETQSDFGRKHPGR
What are the official names of this protein?
Uncharacterized protein 092R.
Protein: YBEY_BIFA0
Sequence: MSVEVANETEWQLDPKVFSELGLWVMHQMRVSTQSELTITFVDPEPIAELHERWMDLQGPTDVMSFPMDELRPGDERNEPEGMLGDIVICPWVAQQQAQAAGHSTMEEMMLLTIHGVLHLLGYDHHTREQERQMFGLQRQLLLTFFALHHGTAWSATLPSGSVNELEVYERKYGTNRELGH
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_PROMM
Sequence: MSNSPKPLADTDTQSWWTKGSTSASLLGIVIFAASFTSDRFIANSLLSLPLMISTLISVLIASWGIPKLRALKMGQVIREDGPQTHQRKSGTPTMGGLLVVPVGLIIGSFVSVNGESSEQLLALSWITLAYMLIGGFDDWRSLTRGTNTGLTPRGKLLLQTAASLIFLAWAGWQHWIDSSIALPLGISIQMGFMIWPLALFVFLAESNATNLTDGLDGLASGCGALVFTGLAVQLMLRGNDGNPVLAGFCMAMAGAWLGFLMHNRNPAQVFMGDTGSLAMGAALSGVAILSNSLWPLLVMGGVFLAESLSVIIQVWVFKATKGPDGVGRRVFRMAPLHHHYEIGGTDEQMVVRRFWLSTGGLVLLGLLLRPTA
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YIDD_ECO8A
Sequence: MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CLPX_NOSP7
Sequence: MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVDLCNEILDEELLDTNGAAAQPTPRAEPPQKRRTQSSSISFNQIPKPREIKKYLDEHVIGQDEAKKVLSVAVYNHYKRLAVIQSKATGKAAADDAVELQKSNILLIGPTGCGKTLLAQTLAKILDVPFAVADATTLTEAGYVGEDVENILLRLLQVADLDIEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTIANVPPQGGRKHPYQDCIQIDTSNILFVCGGAFVGLEKVVDQRVGKKAIGFVQPGEGQTKEKRAADTLRHLAPDDLVKFGMIPEFIGRVPMVAVVDPLDEEALMAILTQPRSALVKQYQKLLKMDNVQLDFKPDALRAIAQEAYRRKTGARALRGIVEELMLDVMYELPSRKDVTRCTVTREMVEKRSTAELIIHPSSLPKPESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: UBP16_XENTR
Sequence: MVKKRGKNLPAQDSLDAEPVCKHLRKALDEGSVKKALVNVEWTVCQECQADNKEKNNSDDELVEDPSVWLCLKCGHRGCGRNSASQHALNHYNTPRSEPHCLVLSVDMWSAWCYLCDNEVPYNRSSRLGQLVDYLQRKAKAKSKSTDSAALDEEVKAEIVAENEVKIEDQEEKPKGQAKWDKASSTQNNSTEPTVKGLSNLGNTCFFNAVMQNLSQTPAVRELLNEAKTLKKPVTVPLPDSSSPTNVEVHLEQQPGPLTLAMWQFLTEMQETKKGVVTPKEVFSQVCKKAIRFKGYQQQDSQELLRYLLDGMRGEEIQRVSLAMSKSLQNTLDEEEIKKIVKDSEKRRTIPNFVDHLFGGELTSTIMCEECHTVSLVHEPFLDLSLPVLDDVIVKKNSQKSSAPAPERKEEEENDDGYIKERDEASPGASKHLQKKAKKAAKKQAKNQRRQLKMQGKTVLLTDVAKQECSEDEEEIAPNNTESEANTRPDDEVPIADGLNTMKSDLSALENGSETIESAMERVTEDTDLDTSGHNTESVEMNAMELVRNMENNNNNNTDVNKTLERTEGSGVDSMEATAAVDNGNADTVCVDDTEAANGLLDCSAASMDNELTNSLNRLKLSSDIEPTQVEIEILPDQQQPHTQIYEVINEDPKTAFSTLSERKDLPLDGYSVLSCLYQFTHKETLTGNNKLLCNVCTRKQASRLNNSNKGEKTFVYTNAKKQMLVSDPSPILTLHLKRFQQNGFNLRKINRHIKFPEVLDLAPFCTSKCKNIPAGESRLLYSLYGVIEHSGSMRSGHYTAFVKLRRPNQQLCEMVLKGVIPEVSGSEPGQGSWYHISDSHVQAVSLSRVLSSQAYLLFYERML
What is the function of this protein?
Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator.  Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis.  Regulates Hox gene expression via histone H2A deubiquitination.  Prefers nucleosomal substrates.  Does not deubiquitinate histone H2B.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 16, Deubiquitinating enzyme 16, Ubiquitin thioesterase 16, Ubiquitin-specific-processing protease 16.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP16 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LRRF2_RAT
Sequence: MGTPGSGRKRTPVKDRFSAEDEALSNIAREAEARLAAKRAARAEARDIRMRELERQQRESSSKDITGTHWSRASTPKRRDMMYDSIKDRSSRVSSLLDEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMDELKEGLRQRDELIEKHGLVIIPESTPNGDVNHEPVVGAITAVSQEAAQVLESAGEGPLDVRLRKLAEEKDELLSQIRKLKLQLEEERQKCSRNDGMSGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDIATLEQSISRLEGQVLRYKTAAENAEKIEDELKAEKRKLQRELRTAQDKIEEMEMTNSHLAKRLEKMKANRTALLAQQ
What is the function of this protein?
May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin.  Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity).
What are the official names of this protein?
Leucine-rich repeat flightless-interacting protein 2, LRR FLII-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the LRRFIP family.
Protein: RL19_SHIDS
Sequence: MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: O16B_CONVC
Sequence: MKLTCMMIVAVLFLTANTFVTADDSGNGMENLFPKAGHEMENLEASNRGKPCHEEGQLCDPFLQNCCLGWNCVFVCI
What are the official names of this protein?
Conotoxin Vc6b, Vc6.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ENV_HV2EH
Sequence: MAHVNNYLLVTLLLISIYGYMGKNFVTVFYGIPAWKNASIPLFCATRNRDTWGTVQCLPDNDDYTEIQLNITEAFDAWDNTVTDQATKDVWSLFETSIKPCVKLTPLCVTMKCNKTWSSASKETTTSSASLRSSTQTLLNEDSKCIQNDSCAGIGLEEMIDCQFKMTGLKRDESKQYKDTWYKQDLVCEKGTRSNESKCYIKTCNTSIIQESCDKHYWDSLRFRYCAPPGFALLRCNDTKYSGFMPNCSKVVVSLYRMMETQTSTWFGFNGTRAENRTYIYWHGKDNRTIISLNSYYNLTMHCKRPGNKMVVPIRTVSGILFHSQPINKRPKQAWCWFKGNWTEAIQEVKETIKNHPRYSGTTNISQIRLAEHARSSDPEVRYMWTNCRGEFLYCNMTFFLNWVENRTGLKRNYASCHIRQIVNTWHKIGRNVYLPPREGELSCNSTVTSLIANIDWIDKNLTNITVSAEVSELYKLELGDYKLVEITPIGFAPTSIKRYSSVTPRNKRGVLVLGFLGFLATAGSAMGAASLTLSAQSRTLLAGIVQQQQQLVDVVKRQQELLRLTVWGTKNLQARVTAIEKYLKDQAQLNSWGCAFRQVCHTTVPWVNESLKPDWNNMTWQQWERQVRFLDANITKLLEEAQIQQEKNMYELQKLNQWDIFSNWFDFTSWMAYIRLGLYIVIGIVVLRIAIYIIQMLARLRKGYRPVFSSPPSYTQQIPIRKDRGQPANEETEEGGGNNEGYRSWPWQIEYIHFPIRQLRDLLIWLYSGCRTLLSKTFQTLQPVLQPLRLPPAYLRYGISWFQEAIQAAARAAGETLASAARTSWGVLRRAAGEIIAIPRRIRQGAELALL
What is the function of this protein?
The gp120-gp41 heterodimer allows rapid transcytosis of the virus through CD4 negative cells such as simple epithelial monolayers of the intestinal, rectal and endocervical epithelial barriers.  Both gp120 and gp41 specifically recognize glycosphingolipids galactosyl-ceramide (GalCer) or 3' sulfo-galactosyl-ceramide (GalS) present in the lipid rafts structures of epithelial cells.  Binding to these alternative receptors allows the rapid transcytosis of the virus through the epithelial cells.  This transcytotic vesicle-mediated transport of virions from the apical side to the basolateral side of the epithelial cells does not involve infection of the cells themselves (By similarity).
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: AROL_ECOL6
Sequence: MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_PICGU
Sequence: MAVGKNKRLSKGKKGLKKRVVDPFTRKEWFDIKAPTTFENRAVGKTLINKSTGLKNAADGLKGRVIEVNLADLQGSEDHAYRKVKLRVDEVQGKNLLTNFHGIDFTSDKLRSLVRKWQSLVEANVTVKTADDYYLRVFAIAFTKRQPNQVKKTTYAQSSKLREIRKKMMEIMQREVSNSTLAQLTQKLIPEVIGREIEKSTQTIFPLQNVHIRKVKLLKQPKFDLGNLMSLHGEGASEEKGKKVSSGFKDVVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMI1_HUMAN
Sequence: MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKSSVNGSSATSSG
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:15386022, PubMed:16359901, PubMed:26151332, PubMed:16714294, PubMed:21772249, PubMed:25355358, PubMed:27827373).  The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A (PubMed:21772249, PubMed:25355358).  In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (PubMed:15386022, PubMed:26151332, PubMed:21772249).
What are the official names of this protein?
Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: DAPF_PSEAE
Sequence: MLLRFTKMHGLGNDFMVLDLVSQHAHVQPKHVKLWGDRNTGIGFDQLLIVEAPSSPDVDFRYRIFNADGSEVEQCGNGARCFARFVQDKRLTVKKSIRVETKGGIIELNIRPDGQVTVDMGPPRLAPAEIPFQAEREALSYEIEVNGQRVELAAVSMGNPHGVLRVENVDSAPVHSLGPQLEVHPRFPKKANIGFLQVLDPHHARLRVWERGVGETQACGTGACAAAVAGIRQGWLQSPVQIDLPGGRLHIEWAGPGQPVMMTGPAVRVYEGQVRL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPT_HAEIE
Sequence: MISQIDKTELLERFLHYVSFHTQSKPNAKHSPSSVGQMKLAMQLQKELIQFGLENVEVSKYAVVTAFLPANDPNLTKTIGLVAHLDTSPQCSGKNVRLEVIEEYRGGDIALGIGEEFISPVYYSFMQKLVGQTLIVTDGTTLLGADNKAGIAEIMTALSILQKENIPHCNIRVAFTPDEEIGLGIHYFPMEKFSCDWAYTIDGGEVGELEYENFNAATAKVRFFGRNIHTGYAKGKMLNALTLACEFQQVFPVDEVPEKTDGKAGFYHLEDFFGDIEQVELTYLIRDFDEQNFAQRKAFIKNQVEKFNAKKGLKKPIELEIQDSYQNMYDVVKNVPQSIELADRAMKAVGIKPNHKPIRGGTDGAFLASKGLACPNIFTGGYNFHSKHELVSLQGMENTVQVIIEMLKCKDL
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_RHOP2
Sequence: MFAVIKTGGRQYRVVPEDVLEVGKIEGDVGTIVQLGEVLMLGGDTPLIGLPTVAGASVAAEVLDHKRGPKVISFKKRRRKNSKRKRGYRDEITVLRITEILADGKSPSVGPRPKRVKAEPAPAADAAE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: VP3_ROTH7
Sequence: MKVLALRHSVAQVYADTQIYTHDETKDDYENAFLISNLTTHNILYLNYSVKTLQILNKSGIAAVEIQKMDELFTLIRCNFTYDYIEDIVYLHDYSYYTNNEIRTDQHWVTKTNIEDYLLPGWKLTYVGYNGSDTRGHYNFSFKCQNAATDDDAIIEYIYSNELDFQNFILKKIKERMTTSLPIARLSNRVFRDKLFKTLVSDHSKVVNVGPRNESMFTFLDHPSIKQFSNGPYLVKDTIKLKQERWLGKRLSQFDIGQYKNMLNVLTTLYQYYDMYHEKPIIYMIGSAPSYWIYDVKQYSNLKFETWDPLDTPYSDLHHKELFYISDVTKLKDNSILYVDIRTDRENMDWKTWRKIVEEQTINNLNIAYRYLSTGKAKVCCVKMTAMDLELPISAKLLHHPTTEIRSEFYLIMDIWDSKNIKRFIPKGVLYSYINNVITENVFIQQPFKLKTLRNEYVVALYALSNDFNNREDVIKLVNNQKNALITVRINNTFKDEPKVGFKDIYDWTFLPTDFETNESIITSYDGCLGMFGLSISLASKPTGNNHLFILSGTNKYFKLDQFANHMSISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYSFDLKRWIYLHSTNKASIEGGRYYEHAPIELIYACRSAREFARLQDDLTVLRYSNEIENYINKVYSITYADDPNYFIGIKFKNIPYEYDVKVPHLTFGVLNISNSMVPDVVAILKKFKSELFRMDVTTSYTYMLSDEIYVANVSGVLSTYFKLYNAFYKEQITFGQSRMFIPHITLSFSDKKVVRIDSTRLNIDFIYLRKIKGDTVFDMAE
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: AWAT2_MOUSE
Sequence: MFWPTKKDLKTAMEVFALFQWALSALVIVTTVIIVNLYLVVFTSYWPVTVLMLTWLAFDWKTPERGGRRFTCVRKWRLWKHYSDYFPLKMVKTKDISPDRNYILVCHPHGLMAHSCFGHFATDTTGFSKTFPGITPYMLTLGAFFWVPFLRDYVMSTGSCSVSRSSMDFLLTQKGTGNMLVVVVGGLAECRYSTPGSTTLFLKKRQGFVRTALKHGVSLIPAYAFGETDLYDQHIFTPGGFVNRFQKWFQKMVHIYPCAFYGRGLTKNSWGLLPYSQPVTTVVGEPLPLPKIENPSEEIVAKYHTLYIDALRKLFDQHKTKFGISETQELVIV
What is the function of this protein?
Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters (PubMed:15220349).  Shows a preference for medium chain acyl-CoAs from C12 to C16 in length and fatty alcohols shorter than C20, as the acyl donor and acceptor, respectively (PubMed:15220349).  Also possesses acyl-CoA retinol acyltransferase (ARAT) activity that catalyzes 11-cis-specific retinyl ester synthesis (PubMed:28096191).  Shows higher catalytic efficiency toward 11-cis-retinol versus 9-cis-retinol, 13- cis-retinol and all-trans-retinol substrates (By similarity).
What are the official names of this protein?
Acyl-CoA wax alcohol acyltransferase 2, 11-cis-specific retinyl-ester synthase, 11-cis-RE-synthase, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, Diacylglycerol O-acyltransferase 2-like protein 4, Long-chain-alcohol O-fatty-acyltransferase 2, Wax synthase, mWS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PGK_STRCO
Sequence: MKTIDELLSEGVAGKRVFVRADLNVPLDGTTITDDGRIRAVVPTVKALADAGARVIVASHLGRPKGAPDPAFSLAPAAARLGELLGADVAFAEDTVGSSAEAVVTGLADGGVAVIENLRFNAGETSKDDAERAAFADKLAGLADVYVGDGFGAVHRKHASVFDLPKRLPHYAGYLIATEVGVLKKLTDEVKRPYVVALGGAKVSDKLAVIDQLLGKADRLLIGGGMAYTFLKAKGYEVGISLLQEDQIPAVKEYIERAEKNGVELVLPVDVLVAPEFPDLKTKAPANPTTVAADAIPADQEGLDIGPETRKLYASKLADAGTVFWNGPMGVFEHPDYAEGTKAVAQALVDAPGFTVVGGGDSAAAVRTLGFDENAFGHISTGGGASLEYLEGKTLPGLAALED
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_ECOBW
Sequence: MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: WSB1_MOUSE
Sequence: MASFPPRVNEKEIVRSRTIGELLAPAAPFDKKCGGENWTVAFAPDGSYFAWSQGYRIVKLVPWSQCRKNFLLHGSKNVTNSSCLKLARQNSNGGQKNKPPEHVIDCGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHIEMVRDLTFAPDGSLLLVSASRDKTLRVWDLKDDGNMVKVLRAHQNWVYSCAFSPDCSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYVWDPHNGDLLMEFGHLFPSPTPIFAGGANDRWVRAVSFSHDGLHVASLADDKMVRFWRIDEDCPVQVAPLSNGLCCAFSTDGSVLAAGTHDGSVYFWATPRQVPSLQHICRMSIRRVMSTQEVQKLPVPSKILAFLSYRG
What is the function of this protein?
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Recognizes type II iodothyronine deiodinase/DIO2.  Confers constitutive instability to HIPK2 through proteasomal degradation (By similarity).
What are the official names of this protein?
WD repeat and SOCS box-containing protein 1, WSB-1.
Protein: PSIE_YERE8
Sequence: MAKNSRSQWIAKNLQRLLNVGLIALAAILVVFLIKETFHLGKVLFVNNQDASSYMLIEGIVIYFLYFEFIALIVKYFESGYHFPLRYFIYIGITAIIRLIIVDHENPIDTLIYSGSILLLVVTLYLANTERLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2885_MYCTU
Sequence: MMARLKVPEGWCVQAFRFTLNPTQTQAASLARHFGARRKAFNWTVTALKADIKAWRADGTESAKPSLRVLRKRWNTVKDQVCVNAQTGQVWWPECSKEAYADGIAGAVDAYWNWQSCRAGKRAGKTVGVPRFKKKGRDADRVCFTTGAMRVEPDRRHLTLPVIGTIRTYENTRRVERLIAKGRARVLAITVRRNGTRLDASVRVLVQRPQQRRVALPDSRVGVDVGVRRLATVADAEGTVLEQVPNPRPLDAALRGLRRVSRARSRCTKGSRRYCERTTELSRLHRRVNDVRTHHLHVLTTRLAKTHGRIVVEGLDAAGMLRQKGLPGARARRRALSDAALATPRRHLSYKTGWYGSSLVVADRWFPSSKTCHACRHVQDIGWDEKWQCDGCSITHQRDDNAAINLARYEEPPSVVGPVGAAVKRGADRKTGPGPAGGREARKATGHPAGEQPRDGVQVK
What is the function of this protein?
An RNA-guided dsDNA endonuclease.  When guided by an RNA derived from the right-end element of its insertion sequence element (IS), cleaves DNA downstream of the transposon-associated motif (TAM).  Cleaves supercoiled and linear DNA in a staggered manner 15-21 bases from the TAM yielding 5'-overhangs.  Binds reRNA, an approximately 150 nucleotide base sRNA derived from the 3' end of its own gene, the right end (RE) of the insertion sequence (IS) plus sequence downstream of the IS.
What are the official names of this protein?
Putative RNA-guided DNA endonuclease Rv2885c.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transposase 35 family.