PharMolix/UniProtQA huggingface dataset:
Protein: DOHH_RAT
Sequence: MVTEQEVEAIGKTLVDSTQPLQARFRALFTLRGLGGPDAISWISRGFEDSSALLKHELAYCLGQMRDPRAIPVLVSVLQDRNQEPMVRHEAGEALGAIGNPKVLGLLKQYSTDPVVEVAETCQLAVRRLEWLQQHPGEATCAGPYLSVDPAPPAAEGDVGRLRETLLDEAQPLFERYRAMFALRNVGGKEAALALAEGLKCGSALFRHEVGYVLGQLQHEAAVSELAATLARTTESPMVRHECAEALGAIARPACLAALREYITDPERVVRESCEVALDMYEYENGQDFQYADGLERLRPPP
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A.  This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine.  Hypusination is unique to mature eIF-5A factor and is essential for its function.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
Protein: NQRD_VIBVU
Sequence: MSSAQNIKKSILAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTLAVTFVTALSNFFVSLIRNHIPNSVRIIVQMAIIASLVIVVDQILKAYLYDISKQLSVFVGLIITNCIVMGRAEAFAMKSAPVPSLIDGIGNGLGYGFVLITVGFFRELFGSGKLFGMEVLPLVNNGGWYQPNGLMLLAPSAFFLIGFMIWAIRTFKPEQVEAKE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: URE3_NOCFA
Sequence: MRLSPHEQERLLLSYAAELARRRQARGLKLNHPEAVALITDHVLEGARDGRSVAELMASGRTVLTRDDVMTGVPEMIHDVQVEATFPDGTKLVTVHQPIA
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP261_YEAST
Sequence: MLFLDSYSLLIQFQRFKNWESPRRFSSSFPLLLFVFKPIFAAKLLKEICSSGVLSYSLSFLKIPLSVMRVILGPLPDDKKLKNDAKYSFMNYFIITCIGIIM
What are the official names of this protein?
Uncharacterized protein YPL261C.
Protein: NRX3B_MOUSE
Sequence: MHLRIHPRRSPPRRPAWTLGIWSLFWGCIVSSVWSSSNVASSSSSSPGSHSQQEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERLQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSVSGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTGRSDKSLSTSIFEGGYKAHAPKWESKDFRPNKVSETSRTTTTSLSPELIRFTASSSSGMVPKLPAGKMNNRDLKPQPDIVLLPLPTAYELDSTKLKSPLITSPMFRNVPTANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQASSKSGHKKQKNKDKEYYV
What is the function of this protein?
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.  May mediate intracellular signaling (By similarity).
What are the official names of this protein?
Neurexin-3-beta, Neurexin III-beta.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: AAEA_KLEP3
Sequence: MKTLTRNILRTAITVILVILAFVAIFRAWVYYTASPWTRDARFSADIVAIAPDVSGLISQVNVKDNQLVKKDQVLFVIDQPRYQKALAEAEADVAYYQTLAQEKRVEAGRRNKLGIQAMSREEIDQANNVLQTVEHQLAKAVASRDLARLDLERTEIRAPADGWVTNLNVYTGEFITRGSTAVALVKENTFYVMAYLEETKLEGVRPGYRAEITPLGSSKTIKGTVDSIAAGVTNASSSSDSKGMASVDSNLEWVRLAQRVPVRIRLDQQQGNLWPSGTTATVVITGKEDRDTSRANFFQKLAMRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DABA_DINSH
Sequence: MTHTATLISVDTLTAAQAGAVQAIPPAFPLSATVAVNPFLGQAGHSLPDTAAVLGKTAGCATTAPRSWFAAEIAAGRITKPAVAEALAAAGLDWPVDKVISAASRQRPAPQALPTVADLAGASEAPGWPAQAEARIAAWVAGHFDQGQALWAAGAPSGTYADWLAFATTDMTPDLAGLPGFRAWLKALPSDPTEALLAAVNTLGLTEAALPLYFHRLAMSLGGWAQAARYRLWQAELAGQTDTTLAELIVIRAVWDAGTLATRPALAAQWDTARAAFAAPVTPSEDDLIDAVLQDAAERSTQADLAQAFAPVAKAEARPALQAAFCIDVRSEVIRRALETCDPGIETLGFAGFFGLTAAHTPTGSCNSEARLPVLLTAGVTSKASGDHDAARITTRVTRAWGRFRQAAVSSFAFVEAAGPFYAGKLVRDTLGLGKADAIPGKPVFDPPLPEEAQIDAAATILNAMSLKSNFAPLVVIAGHGSHVNNNAHASALQCGACGGYGGDVNARLLADLLNQPHVRAGLAARGIAVPEDTIFVAALHDTAQDAITLYADDLSEAHRAAATASLAQARQWCAEAGRLARSERQPSLPGATERDGIAARAQSWAETRPEWGLAGCKAFVVAPRTQTAPAQLDGRVFLHSYDWAQDEGFGVLELILTAPVVVASWISLQYYGSVVAPEVFGGGSKQVHNVTGGMGVLDGGTGALRIGLPIQSVHDGGSFVHDPLRLTIVVNAPQEAITDILARHDGVRALFDNGWLKLLRLEADGTISERYTGDLTWEAFAPGTEAAQAA
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNH2_SYNJA
Sequence: MVGSGVGGVDKVVQPSLKWEGSLWQQGMRRVAGVDEVGRGALAGPVVAAAVILPAHLDPEALSGVRDCKQLRPPQRAHWAERIAQVALAVGIGSASAAEIDQLNIRQATLLAMQRALAQVGEVEHILLDGLPLAELGSRQTALVKGDQLSLSIAAASIVAKVWRDTLMQSWDHQYPGYGWRTNVGYGTQEHRLALQRLGPSPQHRRSFAPLRDLQAGEIGG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCP2_MOUSE
Sequence: MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHAGIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVEAYKTIAREEGIRGLWKGTSPNVARNAIVNCAELVTYDLIKDTLLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYHSAGHCALTMLRKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAAYQSREAPF
What is the function of this protein?
Antiporter that exports dicarboxylate intermediates of the Krebs cycle in exchange for phosphate plus a proton across the inner membrane of mitochondria, a process driven by mitochondrial motive force with an overall impact on glycolysis, glutaminolysis and glutathione-dependent redox balance.  Continuous export of oxaloacetate and related four-carbon dicarboxylates from mitochondrial matrix into the cytosol negatively regulates the oxidation of acetyl-CoA substrates via the Krebs cycle lowering the ATP/ADP ratio and reactive oxygen species (ROS) production (By similarity).  Proton transporter activity is debated, but if it occurs it may mediate inducible proton re-entry into the mitochondrial matrix affecting ATP turnover as a protection mechanism against oxidative stress.  Proton re-entry may be coupled to metabolite transport to allow for proton flux switching and optimal ATP turnover (PubMed:12011051, PubMed:11756659) (By similarity).  Regulates the use of glucose as a source of energy.  Required for glucose-induced DRP1-dependent mitochondrial fission and neuron activation in the ventromedial nucleus of the hypothalamus (VMH).  This mitochondrial adaptation mechanism modulates the VMH pool of glucose-excited neurons with an impact on systemic glucose homeostasis (PubMed:26919426).  Regulates ROS levels and metabolic reprogramming of macrophages during the resolution phase of inflammation.  Attenuates ROS production in response to IL33 to preserve the integrity of the Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages (PubMed:34644537).  Can unidirectionally transport anions including L-malate, L-aspartate and phosphate (By similarity).  Does not mediate adaptive thermogenesis (PubMed:11101840).
What are the official names of this protein?
Dicarboxylate carrier SLC25A8, Mitochondrial uncoupling protein 2, UCP 2, Solute carrier family 25 member 8, UCPH.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: RS30_PLAF7
Sequence: MGKVHGSLARAGKVKNQTPKVPKLDKKKRLTGRAKKRQLYNRRFSDNGGRKKGPNSKA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (Probable).  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable).  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable).  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable).
What are the official names of this protein?
40S ribosomal protein S30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS30 family.
Protein: RLMN_CERSK
Sequence: MTANAPITQDVMTLPRKLPEGGPVNIVGLTREELLAALVAAGTPERQAKMRAGQVWQWVYHWGVRDFAQMTNLAKDYRALLAEHFAIVLPEVVTRQISADGTRKYLIRIAGGHEVETVYIPEEGRGTLCVSSQVGCTLTCSFCHTGTQKLVRNLTAAEIVGQLMLVRDDLGEWPERGAPKDETRLVSNLVLMGMGEPLYNFENVRNAMKVVMDGEGLSLSRRRITLSTSGVVPEIARTAEEIGCQLAISFHATTDEVRDILVPINKRWNIRTLLDSLRDYPRLSNSERITFEYVMLDGVNDTDADARRLVKLISGIPSKINLIPFNEWPGAPYRRSTPERIAAFADIIYKAGYASPIRTPRGEDIMAACGQLKSATERARKSRAQIAAETGL
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPP1_ASPFU
Sequence: MLGFRSPIRLCKLSALGSTRLLPISRPKLFSTAVARYAADMETVNTTKRLARLRQLMQEHKIDVYIVPSEDSHQSEYIAPCDGRREFISGFSGSAGTAIVSMTKAALSTDGRYFNQASKQLDSNWELLKRGVENVPTWQEWTTEQAQGGKVVGVDPALITASGARSLEETLKRNGSSLVGISQNLVDLVWGKDRPAPPREKVRVHPDKFSGKTFQEKIADLRKELEKKKTAGFVISMLDEIAWLFNLRGSDIPYNPVFFAYAIITPTKAELYIDDDKITPEVVAHLGQDVVIKPYNSIFADAKALSEARRKEAGETASKFLLSNKASWALSLSLGGEEHVEETRSPIADAKAIKNEVELAGMRACHIRDGAALIEYFAWLENELVNKKTVLDEVDAADKLEQIRTKHDLFAGLSFDTISSTGPNGAVIHYKPEKGTCSIIDPDAIYLCDSGAQYLDGTTDVTRTFHFGKPTELEKKAFTLVLKGLIAIDTAVFPKGTSGFALDALARQYLWKEGLDYLHGTGHGVGSYLNVHEGPIGIGTRVQYTEVPIAPGNVISDEPGFYEDGKFGIRIENVIMAREVQTTHKFGDKPWLGFEHVTMAPIGRNLIEPSLLSDLELKWVNDYHAEVWDKTHHFFENDEFTRSWLQRETAPITK
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: RL2_RICRO
Sequence: MALKNFNPITPSLRELVQVDKTSLWKGRPLKSLTKGISKTGGRNNQGRITSWHRGGGHKKLYRIIDFKRNKIDVSAIVERIEYDPNRTAFIALIKYEDGEYSYILAPQKLSVGDRVISSQDADIKIGNCLPLKCIPIGTTLHNVEMKVGKGGQIARSAGTSVDLVGKDSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRNRWLGWRPHVRGVAMNPVDHPHGGGEGKTSGGRHPVTPWGFPTKGKKTRKNKRTSKFIVKKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: MPS1_MAGO7
Sequence: MSDLQGRKIFKVFNQDFIVDERYTVTKELGQGAYGIVCAAVNNQTSEGVAIKKVTNVFSKKILAKRALREIKLLQHFRGHRNITCLYDMDIPRPDNFNETYLYEELMECDLAAIIRSGQPLTDAHFQSFIYQILCGLKYIHSANVLHRDLKPGNLLVNADCELKICDFGLARGFSVDPEENAGYMTEYVATRWYRAPEIMLSFQSYTKAIDVWSVGCILAELLGGRPFFKGRDYVDQLNQILHILGTPNEETLSRIGSPRAQEYVRNLPFMAKKPFPTLFPNANPDALDLLDRMLAFDPSSRISVEQALEHPYLHIWHDASDEPDCPTTFNFDFEVVEDVGEMRKMILDEVYRFRQLVRTAPGAGGHGAPHAPQVPIPAGAGQGQWKAEDPRPQEYVGQMNDLEAELAGGLDQRR
What is the function of this protein?
Mitogen-activated protein kinase; part of the MCK1-MKK2-MPS1 MAP kinase (MAPK) signal transduction cascade that is essential for cell wall integrity and plant infection, but not for plant defense responses (PubMed:9770551, PubMed:18344407, PubMed:22321443, PubMed:28799700, PubMed:28424497).  Beside its role in pathogenesis, the MPS1 cascade is active in conidiation and cellular stress responses (PubMed:9770551).  Targets downstream of the MPS1-MAPK pathway include transcription factors MIG1 and SWI6, as well as GSK1 and MPG1 (PubMed:18344407, PubMed:22321443, PubMed:28424497).
What are the official names of this protein?
Mitogen-activated protein kinase MPS1, MAPK MPS1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: RECR_PARUW
Sequence: MRYPEHLLKLIHILKKFPGVGHKSAERFAFHLLNWPMEHLIELSETVKNTKDKIKQCLNCGCLTDEAACYFCDINQRDSQIICVTAFPRDVFSIEETHEYRGLYHVLGGVLSPLENRGPEHLSISRLKHRIQDLQIKEVVIALDSTLEGDATALFLKQELAADDIQISRLAFGLPMGSSLDYVDGGTLARALAGRSRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: KDSB_DESVH
Sequence: MSAPRTCYGIIPARYASSRFPGKPLAEILGRPMFWHVYDRARRCAAFDEVALATDDARIADAANVLGVPCVMTAEHHPSGTDRVHEAAMRLGVPDDAVVVNIQGDEPALDPRMLDQLVAPFADASVRVATLAMALSAQEAQSPDRVKVVVAANGDALYFSRADIPFVRDGDVGGDTAGRLGHIGLYAFRMEALRRFTQLPPSRLEQTEKLEQLRLLENGIAIRVVPTTYRTHGVDRPEDIDVIINLLRENDG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_SODGM
Sequence: MAQQTPLYEEHHASGAKMVDFHGWMMPLHYGSQLDEHHQVRRDVGMFDVSHMTIVDLAGPRTRDFLRHLLANDVAKLTVPGKALYTGMLNASGGVIDDLIVYFLSEIEFRLVVNSETRDKDVEWITRHAEPYQVTVTVRDDLALIAVQGPQAQSKTQTLFSSQQRQAVSGMKPFFGVQANELFIATTGYTGEAGYEIALPATQAADFWRQLLAAGVKPCGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTITWRPEGRDFIGREALEAQRAAGDGEQLVGLVMTEKGVLRNGLPVHFTDAAGNMQQGIITSGSFSPTLGVSIALARVPAGIGQQAIVLIRNREMPVKVTKPGFVRAGKAVAQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: 6PGL_SALTI
Sequence: MKQTVYTASPESQQIHVWSLNHEGTLTLVQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHHGRFVFVGSYNAGNVSVTRLQDGLPVELVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTLSDDGHLVAQEPAEVNTVEGAGPRHMVFHPNRQYAYCVNELNSSVDVWQLKNPHGEIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSVEGFQPTEAQPRGFNIDNSRKYLIAAGQKSHHIAVYEITGTQGLLTEKGRYAVGQGPMWVVVNAY
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: VPS27_NEOFI
Sequence: MAGWFSSTSLLDEQVERATSSSLEDIALNLEISDLIRSKSVQPKEAMRSLKRRLENRNPNVQIATLKLTDTCVKNGGSHFLAEIASREFMDNLVSLLTTEGAPLNTDVKEKMLELIQDWAMAAQGRMDLNYLGETYRRLQSEGFRFPPKNEISGSMLESSAPPEWIDSDVCMRCRTPFSFMNRKHHCRNCGNVFDAQCSSKTLPLPHLGILQPVRVDDGCYAKLTSKSSLPSNLSDRSAFKNHSITKANAMEPRGARAEGGFDDDLRRALQLSLEEAQNKGSSGYVPSTRINDEPAKTTTQANHEEEEDADLKAAIEASLRDMEEHKKKHAAALKSNAAATDSSARDTTAATPLPKNPYELSPVEVENIHLFAALVDRLQHQPPGTILREPQIQELYESIGALRPKLARSYGETMSKHDTLLDLHAKLSTVVRYYDRMLEERLSSAYSQHSLGYGTVPGGSPYPNMYPTMPSHVPEGKTGAENFYYGNPVADRAPPVNNTYGYPQSSRDIREPAAAPSGPISSGMYNQPSQAVPQNPPWNGNAPSVASPQPSAPSTPFPNNPSGYPGPSASTQYYASAPHPEQDPNAYSSPRPGETDISHQPSPIMRRDSYYQSAGAPVTARASAPEQSPPTDQGQSPAYMQYGDSHPVQSTGQPTPQYQPTAPPPQSYYFQHQPQQSAPLPTHSQTPGAPHGTYPGGDVSPISAPAHAVHYQQVAPTKPAVEESLIEL
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 27.
What is the protein family that this protein belongs to?
Belongs to the VPS27 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1296_HAEIN
Sequence: MINRKILLTSLLLIFTVLSACSREKNTCRVVKISDGDTLTCLTKGNKSIKVRLAEIDAPEKSQAFGQKSKKTLSDLVYQKNVRLARKGKDRYQRTLAVVYYQKQNINLEMVKQGMAWAYKQYSHDPIYLQAQENAQAKGIGLWADNNPIEPSQWRRQEKINMAFDYQTFPSSISLFPT
What are the official names of this protein?
Uncharacterized endonuclease HI_1296.
What is the protein family that this protein belongs to?
Belongs to the thermonuclease family.
Protein: NRDR_BURO0
Sequence: MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELNLPAVVKKDGSRTEFDRRKIVASMQLALRKRPVAADAIDAAVARIEYQLLATGEREVRSEKLGELVMNELRGLDTIAYVRFASVYRRFEDVSEFADVIEEFRRASPAKTPRKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: TFAX_ECOLI
Sequence: MLPQHSDIEIAWYASIQQEPNGWKTVTTQFYIQEFSEYIAPLQDAVDLEIATEEERSLLEA
What is the function of this protein?
Might play a role in cell growth during glycolysis.
What are the official names of this protein?
Protein TfaX.
What is the protein family that this protein belongs to?
Belongs to the tfa family.
Protein: APAG_SHIF8
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: ISPD_YERPS
Sequence: MSNFAVSLPEVIAVLPAAGIGSRMLADCPKQYLTVGGKTIIEHAIFSLLHHPRIQRVIVVIHPQDTQFSRLSVAQDPRISTVYGGDQRANSVMAGLQLAGQAEWVLVHDAARPCLHLDDLSRLLSITECSQVGGILAAPVRDTMKRAEPGIQAIAHTVDRQDLWHALTPQLFPLELLKLCLSRALREGVAVTDEASALEYCGYHPILVTGRSDNIKVTRPEDLALAEFYLTQRQSLNNDSL
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: G3P_SALTI
Sequence: MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDAEYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGIFLTDETARKHITAGAKKVVLTGPSKDNTPMFVKGANFDKYEGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFAH_ECOL5
Sequence: MAYSQPSFALLCRNNQTGQEFNSGDTSFRVNVSPVVQYDKSISVLDLSQLVSCQNEDSTGQNYDYLKILKGSGFSPALDTKTYGRLDFTSRPTGYARQLPLQFDLQVTEAFYQYGVWKPFPAKLYLYPEPGVFGKVINNGDLLATLYVNKFSTKGQEAGERNFTWRFYATNDVHIQTGTCRVSSNNVKVDLPSYPGGPVTVPLTVRCDQTQSVSYTLSGPVTGSGNTVFANTAASGAGGVGVQLSDKAGPVPAGQPRSLGQVGSSPVSLGLKASYALTGQASLTPGAVQSVINVTFSYN
What is the function of this protein?
A minor fimbrial subunit.  This protein is necessary for full expression of S-specific binding.  S-fimbrial adhesins enable pathogenic E. coli causing urinary-tract infections or newborn meningitis to attach to glycoproteins terminating with alpha-sialic acid-(2-3)-beta-Gal.
What are the official names of this protein?
S-fimbrial protein subunit SfaH.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: CECB_SPOLT
Sequence: ILSFVFACLLALSAVSAAPEPRWKVFKKIEKMGRNIRDGIVKAGPAIEVLGSAKALGK
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-B.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPPH_BURVG
Sequence: MLDREGFRPNVGIILLNARNEVFWGKRLREHSWQFPQGGIKYGETPMQAMYRELHEETGLHPEHVKIIGRTRDWLRYEVPDKFIKREVRGHYRGQKQIWFLLRMVGRDCDICLRATDHPEFDAWRWNEYWVPLDAVIEFKRDVYQLALTELSRFLRRPAQRAEKPRGPRPLRYPRIGGAPAQQTLTIVDTSVVCSEIEVEARTLDEMPPRVIIGK
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RL24_NEIM0
Sequence: MNKIIKGDRVVVIAGKDKGKQGQVVRVLGDKVVVEGVNVVKRHQKPNPMRGIEGGIITKEMPLDISNIAILNPETNKADRVGIKLIENEGKVKRVRFFKSNGSIIGA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.