PharMolix/UniProtQA huggingface dataset:
Protein: IFNG_CALJA
Sequence: MKYTSYILAFQLCVVLGSLGCYCQDPYVKEAENLKKYFNAGDSDVADNGTLFLDILRTWREEGDRKIMQSQIISFYFKLFKNFKDNQSIQKSMETIKEDMNVKFFNSNKRKQDDFERLTNYSVNDLNVQRKAIHELIQVMAELSPAPKIGKRRRSQTLFRGRRASQ
What is the function of this protein?
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.  Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation.  Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes.  Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription.  Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits.  In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading.  Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference.  Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity).  Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).
What are the official names of this protein?
Interferon gamma, IFN-gamma.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZNF70_HUMAN
Sequence: MEVPPATKFGETFAFENRLESQQGLFPGEDLGDPFLQERGLEQMAVIYKEIPLGEQDEENDDYEGNFSLCSSPVQHQSIPPGTRPQDDELFGQTFLQKSDLSMCQIIHSEEPSPCDCAETDRGDSGPNAPHRTPQPAKPYACRECGKAFSQSSHLLRHLVIHTGEKPYECCECGKAFSQSSHLLRHQIIHTGEKPYECRECGKAFRQSSALTQHQKIHTGKRPYECRECGKDFSRSSSLRKHERIHTGERPYQCKECGKSFNQSSGLSQHRKIHTLKKPHECDLCGKAFCHRSHLIRHQRIHTGKKPYKCDECGKAFSQSSNLIEHRKTHTGEKPYKCQKCGKAFSQSSSLIEHQRIHTGEKPYECCQCGKAFCHSSALIQHQRIHTGKKPYTCECGKAFRHRSALIEHYKTHTREKPYVCNLCGKSFRGSSHLIRHQKIHSGEKL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 70, Zinc finger protein N27C7-1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ETR1_CUCSA
Sequence: METCYCIEPQWPADELLMKYQYISDFFIALAYFSIPLELIYFVKKSAVFPYRWVLVQFGAFIVLCGATHLINLWTFTMHSRTVAVVMTTAKVLTAVVSCATALMLVHIIPDLLSVKTRELFLKNKAAELDREMGLIRTQEETGRHVRMLTHEIRSTLDRHTILKTTLVELGRTLALEECALWMPTRTGLELQLSYTLHQQNPVGYTVPINLPVISQVFSSNRAVKISPNSPVASLRPRAGRYVAGEVVAVRVPLLHLSNFQINDWPELSTKRYALMVLMLPSDSARQWRVHELELVEVVADQVAVALSHAAILEESMRARDPLMEQNVALDLARREAETANHARNDFLAVMNHEMRTPMHAIIALSSLLQETELTPEQRLMVETILKSSNLLATLINDVLDLSRLEDGSLQLDIGTFNLHAVFKEVLNLIKPVTLVKKLSLTLHLGLDLPVFAVGDEKRLMQAILNVVGNAVKFSKEGSISISAIVAKAETFREIRVPDFHPVPSDSHFYLRVQVKDTGSGISPQDIPKLFTKFAQTTVGPRNSCGSGLGLAICKRFVNLMEGHIWLESEGLGKGCTATFIVKLGIAEQSNESKLPFTSKIHENSIHTSFPGLKVLVMDDNGVSRSVTKGLLVHLGCEVTTAGSIEEFLRVVSQEHKVVFMDICTPGVDGYELAIRIREKFAKCHERPFMVVLTGNSDKVTKESCLRAGMDGLILKPVSIDKMRSVLSELIERRVLFETS
What is the function of this protein?
May act early in the ethylene signal transduction pathway, possibly as an ethylene receptor, or as a regulator of the pathway.
What are the official names of this protein?
Ethylene receptor 1, CS-ETR1.
What is the protein family that this protein belongs to?
Belongs to the ethylene receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: POGK_HUMAN
Sequence: MESTAYPLNLSLKEEEEEEEIQSRELEDGPADMQKVRICSEGGWVPALFDEVAIYFSDEEWEVLTEQQKALYREVMRMNYETVLSLEFPFPKPDMITRLEGEEESQNSDEWQLQGGTSAENEESDVKPPDWPNPMNATSQFPQPQHFDSFGLRLPRDITELPEWSEGYPFYMAMGFPGYDLSADDIAGKFQFSRGMRRSYDAGFKLMVVEYAESTNNCQAAKQFGVLEKNVRDWRKVKPQLQNAHAMRRAFRGPKNGRFALVDQRVAEYVRYMQAKGDPITREAMQLKALEIAQEMNIPEKGFKASLGWCRRMMRRYDLSLRHKVPVPQHLPEDLTEKLVTYQRSVLALRRAHDYEVAQMGNADETPICLEVPSRVTVDNQGEKPVLVKTPGREKLKITAMLGVLADGRKLPPYIILRGTYIPPGKFPSGMEIRCHRYGWMTEDLMQDWLEVVWRRRTGAVPKQRGMLILNGFRGHATDSVKNSMESMNTDMVIIPGGLTSQLQVLDVVVYKPLNDSVRAQYSNWLLAGNLALSPTGNAKKPPLGLFLEWVMVAWNSISSESIVQGFKKCHISSNLEEEDDVLWEIESELPGGGEPPKDCDTESMAESN
What are the official names of this protein?
Pogo transposable element with KRAB domain.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASTA_YERPB
Sequence: MMKVRPVERRDLADIFELAGKTGVGMTSLPQNEQHLAARIERALNTWQGSLDPGEQGYLFVLEDSEQQKVVGVSAIEVAVGLNDPWYNFRVGTLVHASKALNVYKSVPTLFLSNDHTGYSELCTLFLDPDYRKDKNGPFLSKVRFLFIAAFRQYFSRKVIAEMRGYTDEQGRSPFWESVGRHFFSIEFAKADYLSGTGQKAFIAELMPKHPLYVDFLAEEARAVIGQVHPHTAPARAVLETEGLQYQGYVDIFDGGPTLEANTDDVRAVRDSSKRTVVIKDYDIEDYDIDPNGRLYLVANDHYHHFRAILMNTHLSDERLRLTPESAEALGVAAGDSVRIVSLFAPETKR
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: RPP2B_ARATH
Sequence: MAFASSSSSIVLSKCEFDVFVSFRGADTRHDFTSHLVKYLRGKGIDVFSDAKLRGGEYISLLFDRIEQSKMSIVVFSEDYANSWWCLEEVGKIMQRRKEFNHGVLPIFYKVSKSDVSNQTGSFEAVFQSPTKIFNGDEQKIEELKVALKTASNIRGFVYPENSSEPDFLDEIVKNTFRMLNELSPCVIPDDLPGIESRSKELEKLLMFDNDECVRVVGVLGMTGIGKTTVADIVYKQNFQRFDGYEFLEDIEDNSKRYGLPYLYQKLLHKLLDGENVDVRAQGRPENFLRNKKLFIVLDNVTEEKQIEYLIGKKNVYRQGSRIVIITRDKKLLQKNADATYVVPRLNDREAMELFCLQVFGNHYPTEEFVDLSNDFVCYAKGLPLALKLLGKGLLTHDINYWKKKLEFLQVNPDKELQKELKSSYKALDDDQKSVFLDIACFFRSEKADFVSSILKSDDIDAKDVMRELEEKCLVTISYDRIEMHDLLHAMGKEIGKEKSIRKAGERRRLWNHKDIRDILEHNTGTECVRGIFLNMSEVRRIKLFPAAFTMLSKLKFLKFHSSHCSQWCDNDHIFQCSKVPDHFPDELVYLHWQGYPYDCLPSDFDPKELVDLSLRYSHIKQLWEDEKNTESLRWVDLGQSKDLLNLSGLSRAKNLERLDLEGCTSLDLLGSVKQMNELIYLNLRDCTSLESLPKGFKIKSLKTLILSGCLKLKDFHIISESIESLHLEGTAIERVVEHIESLHSLILLNLKNCEKLKYLPNDLYKLKSLQELVLSGCSALESLPPIKEKMECLEILLMDGTSIKQTPEMSCLSNLKICSFCRPVIDDSTGLVVLPFSGNSFLSDLYLTNCNIDKLPDKFSSLRSLRCLCLSRNNIETLPESIEKLYSLLLLDLKHCCRLKSLPLLPSNLQYLDAHGCGSLENVSKPLTIPLVTERMHTTFIFTDCFKLNQAEKEDIVAQAQLKSQLLARTSRHHNHKGLLLDPLVAVCFPGHDIPSWFSHQKMGSLIETDLLPHWCNSKFIGASLCVVVTFKDHEGHHANRLSVRCKSKFKSQNGQFISFSFCLGGWNESCGSSCHEPRKLGSDHVFISYNNCNVPVFKWSEETNEGNRCHPTSASFEFYLTDETERKLECCEILRCGMNFLYARDENDRKFQGIRVTDTVERTSSEALVTIRGQSHSRIEERRYGRIRDEIMDMTGSSMIGGPES
What is the function of this protein?
Disease resistance protein that cooperates with RPP2A to confer resistance to Hyaloperonospora parasitica isolate Cala2.
What are the official names of this protein?
Disease resistance protein RPP2B.
What is the protein family that this protein belongs to?
Belongs to the disease resistance TIR-NB-LRR family.
Protein: HIS51_CAMJJ
Sequence: MIALIDYKAGNLNSVAKAFEKIGAINFIAKNPKDLQKADKLLLPGVGSFKEAMKNLKELGFIEALKEQVLVQKKPILGICLGMQLFLERGYEGGVCEGLGFIEGEVVKFEEDLNLKIPHMGWNELEILKQDPLYQGINNKSDFYFVHSFYVKCKDEFVSAKAQYGHKFVASLQKDRIFATQFHPEKSQNLGLKLLENFARL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 1, IGP synthase glutaminase subunit 1, IGP synthase subunit HisH 1, ImGP synthase subunit HisH 1, IGPS subunit HisH 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_STRA5
Sequence: MKLLEERILKDGDVLGENILKVDSFLTHQVDFELMQEIGKVFADKYKEAGITKVVTIEASGIAPAVYAAQALGVPMIFAKKAKNITMTEGILTAEVYSFTKQVTSQVSIVSRFLSNDDTVLIIDDFLANGQAAKGLLEIIGQAGAKVAGIGIVIEKSFQDGRDLLEKTGVPVTSLARIKAFENGRVVFAEADA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_COXB2
Sequence: MPRSTNKGPFVDHHLMKKVDQAQKEGSKRPIKTWSRRSMVVPEMVGLTIAIHNGRQHVPVYISENMVGHKLGEFAITRTFRAHSGDRKAKKEGEK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NIFM_AZOVI
Sequence: MASERLADGDSRYYLLKVAHEQFGCAPGELSEDQLQQADRIIGRQRHIEDAVLRSPDAIGVVIPPSQLEEAWAHIASRYESPEALQQALDAQALDAAGMRAMLARELRVEAVLDCVCAGLPEISDTDVSLYYFNHAEQFKVPAQHKAHILVTINEDFPENTREAARTRIETILKRLRGKPERFAEQAMKHSECPTAMQGGLLGEVVPGTLYPELDACLFQMARGELSPVLESPIGFHVLYCESVSPARQLTLEEILPRLRDRLQLRQRKAYQRKWLVCLLQQNATLENLAHG
What is the function of this protein?
Required for the activation and stabilization of the iron-component (NifH) of nitrogenase.  Probable PPIase.
What are the official names of this protein?
Putative peptidyl-prolyl cis-trans isomerase NifM, PPIase NifM, Rotamase NifM.
What is the protein family that this protein belongs to?
Belongs to the PpiC/parvulin rotamase family.
Protein: RK35_THAPS
Sequence: MPKLKTRKAALKRYKKTGAGNFLRRHAYKGHLLMKKSNAQKRKLSQRVCVSSGDSKPIKLMLPY
What are the official names of this protein?
50S ribosomal protein L35, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CP6T1_DROME
Sequence: MIAVFSLIAAALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWHWRRLGVPFVPAAPFVGNVWNLLRGACCFGDQFRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVEDFAQFSSRFETTDPTCDTMGSQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQLCALFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPKRLLHLFTMFFFPRLSHRVGTHLYSEEYERFMRKSMDYVLSQRAESGENRHDLIDIFLQLKRTEPAESIIHRPDFFAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERTLPEMRFDPKAFVLTAHNGTYLRFVKNSL
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Probable cytochrome P450 6t1, CYPVIT1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: ASNA_BACHK
Sequence: MYQSLMTVRETQIAIKEVKTFFEDQLAKRLELFRVSAPLFVTKKSGLNDHLNGVERPIEFDMLHSGEELEIVHSLAKWKRFALHEYGYEAGEGLYTNMNAIRRDEELDATHSIYVDQWDWEKIVQKEWRTVDYLQKTVLTIYGIFKDLEDHLFEKYPFLGKYLPEEIVFVTSQELEDKYPELTPKDREHAIAKEHGAVFIIGIGDALRSGEKHDGRAADYDDWKLNGDILFWHPVLQSSFELSSMGIRVDSKSLDEQLTKTGEDFKREYDFHKGILEDVLPLTIGGGIGQSRMCMYFLRKAHIGEVQSSVWPDDLREACKKENIHLF
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1636_RHOCS
Sequence: MLYWALIFFVVALVAGVLGFGGISSASAGIAQILFFIFLVIFVVSLIMGLVRRR
What are the official names of this protein?
UPF0391 membrane protein RC1_1636.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LHB1_RHOCA
Sequence: MADKNDLSFTGLTDEQAQELHAVYMSGLSAFIAVAVLAHLAVMIWRPWF
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-870 beta chain, Antenna pigment protein beta chain, LH-2.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: TYSY_BRAHW
Sequence: MQNYLDLLKKVLEEGEETKDRTGVGTRRIFGPQLRFKFEGNKIPIITTKRVFMKGVIIELLWFLQGSTNIKFLLENNVHIWDEWADDMGELGPVYGKQWRAWETKEGNKIDQISNIVNTLRNNPASRRIILNAWNVGEIDQMHLPPCHMMCQFSVNSKGGIITHLYQRSADLFLGVPFNISSYAILTRLLAMHSGLHASELIMTFGDAHIYNNHIEQVKLQLSREPLEQTTELFIDNRPNIFSHVYEDFKLEGYKYYPTIKAEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FYV10_ASPFU
Sequence: MAAELTSTKLNAENHLLLDQPLLRLPHELARRNFKSVQRLVEREREYVIPALKEAANASLSNAQTPDQTLAALDSMLARMQNLKRKMESIQQEEKKVQNQSRKRIQHLEHLHQIPSLADVKYDQWSRIRLDRLVVDHMLRSGYTESAQQLAQEKGIEDLVDLDVFVQCQRIAQSLRRGETKDALQWCNENKAALKKSQFNLEFELRLQQYIEMLRTGDRGKLMDAMAHAKRYLTPYTETQSKEIHRAAGLLAFPQDTKAEPYKLTDLQSMYSFDRWNYLSDLFIRTHHELLSLPSSPLLHIALSAGLSALKTPSCHSAYTSSSSNFLSTTTSVCPICSTELNELARNMPYAHHAKSYVESDPIVLPNGRIYGQQRLLDMSKKLGCVETGKVKDPTTGEIFDKSEMKKVYIM
What is the function of this protein?
Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
What are the official names of this protein?
Protein fyv10.
What is the protein family that this protein belongs to?
Belongs to the FYV10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GCSH_BACAC
Sequence: MSIPNNLRYSEEHEWVKTEGNEVVIGITHFAQNELGDIVFVELPEVGATIEADEPFGSVESVKTVSELYAPVSGKVVAVNEELSDQPELVNESPYEGAWMVKVELSDASQVEKLLTAEKYAEMTNQD
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: YCBK_ECOLI
Sequence: MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNNLHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTRKPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRAGGVGYYPRSNFVHIDTGPARHW
What are the official names of this protein?
Uncharacterized protein YcbK.
What is the protein family that this protein belongs to?
To H.influenzae HI_1666.
Protein: GNAT1_CANLF
Sequence: MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMSDIIQRLWKDSGIQACFERASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYDGPNTYEDAGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
What is the function of this protein?
Functions as signal transducer for the rod photoreceptor RHO.  Required for normal RHO-mediated light perception by the retina (By similarity).  Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO.  The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state.  Activated RHO promotes GDP release and GTP binding.  Signaling is mediated via downstream effector proteins, such as cGMP-phosphodiesterase (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein G(t) subunit alpha-1, Transducin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Cell projection, cilium, photoreceptor outer segment. Membrane; Peripheral membrane protein. Photoreceptor inner segment. Note=Localizes mainly in the outer segment in the dark-adapted state, whereas is translocated to the inner part of the photoreceptors in the light-adapted state. During dark- adapted conditions, in the presence of UNC119 mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light.
Protein: VP5_IBDVC
Sequence: MVSRDQTNDRSDDKPARSNPTDCSVHTEPSDANNRTGVHSGRHPGEAHSQVRDLDLQFDCGGHRVRANCLFPWIPWLNCGCSLHTAEQWELQVRSDAPDCPEPTGQLQLLQASESESHSEVKHTSWWRLCTKRHHKRRDLPRKPE
What is the function of this protein?
Plays a role in the release of virion progenies by disrupting the host plasma membrane.
What are the official names of this protein?
Protein VP5.
What is the protein family that this protein belongs to?
Belongs to the avibirnavirus/aquabirnavirus VP5 protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: RSMH_POLNA
Sequence: MVKGTWTHRTVLLNEAITALQVNPDGHYIDATFGRGGHSRLLLSQLSALGRVTAFDKDLDAIAEAQSIDDPRFSIRHQGFMHLDQMPQASVAGVLMDLGVSSPQIDNPERGFSFRNEGPLDMRMDTTRGQSVAEWLQDASIEAMTEVIRDYGEERFAGLVARAIDRRRQEHGPLQTTAELADVVASAVKTREPGKDPATRTFQALRIFINAELEELQQALQASLKVLQPGGRLVVISFHSLEDRIVKQFIAAHSREVYDRRAPFAAPKVMQLKALGRTKASEEEVAGNPRSRSAVMRVAERTGEAA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYR1_CAEEL
Sequence: MGRLRAFLLFSGTLAVISTVHADFNCSQAPDSDMVQTCHMLQEWDSAARKAIRKRQAFNAGAPGVQGFSPSNPPRFAPSAQGCMNIACICPYMGGRMANGCILPNGQPYLMAYRKEYRMMSDNERQRWHNALIQLKRSGEYDRLSVMHRQVGSASGAHSGPGFLVWHREYMKRMEIALRMIDPGISMPYWDSVLESYLPDPRDSIMFGPQFMGMTDASGQLVSGPFAGFRTLEGRPNIIRRMATEGKMFTEQNINNLMAQNDLVSVMAFTAPQGGCPFRPYFGALEYTHASIHLWMGGDMKPPSTSANDPVFFLHHTFVDFIWEMWRQNHQNRFARENQYPPDIAACANSQHFSYAQMRPWDKINRDGLSNAYTDNLYHYAPRPTCNRNNANCGSQYLFCDTRGNPHCVAKVKPGGLCRGFEGLDSCYMGTCVAGWCRGGQQFQQPAQTTAVATVQQPQQQPQQQQPQQQRPATTPQSNCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNFCTRRRQWMAENCQATCGWCNMNEAQLCASVARQSRRVRRNAKFWLTEPDADDFVDDFMLDYGR
What are the official names of this protein?
Putative tyrosinase-like protein tyr-1.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
Protein: THII_ARCFU
Sequence: MMEKVAVVHYGEIGIKGKNREFFERKLIEAIKRATGMRVRRKYGRIEVEYREGLESRMAKIPGIRYFGVGFKTELNLESIKKAALSVLPESFKTFKVDTSRSNKNFPMNSVEVNRKVGAFIVEKTGKKVDLTNPDVTVWIEICEKEAYVYSKRYEGIGGLPVGVAGKVVALISGGIDSPVAAFMAMKRGCEVVAVHFFNQTMHSPKVREKIRMLAEKLAEYQGKIKLYMVPFKEVQFEIINRVPPKLRMVVYRRSMMRMANLIAEKEGCKAVVTGDSLSQVASQTLDNINVIYSASKLAVLPPLIGMDKEEIVAIAKRIETYEISILPYEDCCSFMVAQHPETRAKIEDVVKYEGFEELERKAVEESEILEVGS
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAEH_ESCF3
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGIGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: TCP9_ARATH
Sequence: MATIQKLEEVAGKDQTLRAVDLTIINGVRNVETSRPFQVNPTVSLEPKAEPVMPSFSMSLAPPSSTGPPLKRASTKDRHTKVEGRGRRIRMPATCAARIFQLTRELGHKSDGETIRWLLENAEPAIIAATGTGTVPAIAMSVNGTLKIPTTTNADSDMGENLMKKKRKRPSNSEYIDISDAVSASSGLAPIATTTTIQPPQALASSTVAQQLLPQGMYPMWAIPSNAMIPTVGAFFLIPQIAGPSNQPQLLAFPAAAASPSSYVAAVQQASTMARPPPLQVVPSSGFVSVSDVSGSNLSRATSVMAPSSSSGVTTGSSSSIATTTTHTLRDFSLEIYEKQELHQFMSTTTARSSNH
What are the official names of this protein?
Transcription factor TCP9.
What are the subcellular locations of this protein?
Nucleus.
Protein: RJ21_FRAAN
Sequence: LQLSYRPRVMIMAVMFVFCINKGYDIY
What are the official names of this protein?
Uncharacterized protein RJ21.
Protein: KPC1B_CAEEL
Sequence: MLFTGTVRVRVLEARQLRPTEWSRRFRQDEAATAAIDSYVNVDWDEYHIGKTQVRPKTNEPRWNEEFTASGVHQGKAIGFSVFHSCVMPPDDFVANTRIAFDQLKIGSANDIWVDLEPHGQLHVVVEMHGTNVEDVHSHNKTRVFKERTNAFNDRQRRGAMRRKIHEVTGHKFMALFLRQPTFCAHCKEFIWGIGKQGYQCQICTVVVHKRCHEDVVWKCPGNKADAVEELGKEIQETGAGRFNINMPHRFSVHSYKRPTFCDHCGSMLYGLINQGLQCSTCKLNVHKRCQRNVANNCGINAKQMAAELAQLGLTGDKMSIRSKKKPSIMTDTSTDISGSSNSENSGYLQQISEDDSGTTSSRSASKVPGGTLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILSLAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQFLHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQEMEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAFMTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSDFTKEEPVLTPSDPAVVRAINQDEFRGFSFINPHFTY
What is the function of this protein?
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins.  PKC also serves as the receptor for phorbol esters, a class of tumor promoters.  Involved in neuropeptide secretion in motor axons.  Likely to act via the extracellular signal-regulated kinase/mitogen-activated protein kinase (ERK/MAPK) pathway in the signaling response to various sensory neurons; temperature, odor, taste, and osmolality.  Its role in regulation differs depending on the neuron in which it is acting; thermosensation in AFD neurons, osmolality in ASH neurons, olfactory perception in AWA and AWC neurons.  Promotes dauer formation mediated by the insulin/IGF pathway.  Required for resistance to antimitotic toxins.
What are the official names of this protein?
Protein kinase C-like 1B, PKC1B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Associated with membranes and the cytoskeleton.
Protein: SPP24_BOVIN
Sequence: MEKMAMKMLVIFVLGMNHWTCTGFPVYDYDPASLKEALSASVAKVNSQSLSPYLFRAFRSSVKRVNALDEDSLTMDLEFRIQETTCRRESEADPATCDFQRGYHVPVAVCRSTVRMSAEQVQNVWVRCHWSSSSGSSSSEEMFFGDILGSSTSRNSYLLGLTPDRSRGEPLYEPSREMRRNFPLGNRRYSNPWPRARVNPGFE
What is the function of this protein?
Could coordinate an aspect of bone turnover.
What are the official names of this protein?
Secreted phosphoprotein 24, Spp-24, Secreted phosphoprotein 2.
What is the protein family that this protein belongs to?
Belongs to the SPP2 family.
What are the subcellular locations of this protein?
Secreted.