PharMolix/UniProtQA huggingface dataset:
Protein: PBPC_BACSU
Sequence: MLKKCILLVFLCVGLIGLIGCSKTDSPEDRMEAFVKQWNDQQFDDMYQSLTKDVKKEISKKDFVNRYKAIYEQAGVKNLKVTAGEVDKDDQDNKTMKHIPYKVSMNTNAGKVSFKNTAVLKLEKTDDEESWNIDWDPSFIFKQLADDKTVQIMSIEPKRGQIYDKNGKGLAVNTDVPEIGIVPGELGDKKEKVIKELAKKLDLTEDDIKKKLDQGWVKDDSFVPLKKVKPDQEKLVSEATSLQGVTRTNVSSRYYPYGEKTAHLTGYVRAITAEELKKKKEGTYSDTSNIGIAGLENVYEDKLRGTTGWKIYVPQTGEVIAEKKAKDGEDLHLTIDIKTQMKLYDELKDDSGAAVALQPKTGETLALVSAPSYDPNGFIFGWSDKEWKKLNKDKNNPFSAKFNKTYAPGSTIKPIAAAIGIKNGTLKADEKKTIKGKEWQKDSSWGGYSVTRVSERLQQVDLENALITSDNIYFAQNALDMGADTFTKGLKTFGFSEDVPYEFPIQKSSIANDKLDSDILLADTGYGQGQMQMSPLHLATAYTPFVDNGDLVKPTLIKKDSQTADVWHKQVVTKEGAADITKGLKGVVEDERGSAYQPVVKGITVAGKTGTAELKTSKDDKDGTENGWFVGYDYENKDLLVAMMIQNVQDRGGSHYVVEKAKKQFQSN
What is the function of this protein?
Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis (Probable).  Probably required for both cortical and vegetative peptidoglycan synthesis (Probable).  Although not usually required for cell division, in the absence of PBP 2B (pbpB) it becomes essential.  Confers resistance to oxacillin and cephalexin (PubMed:28792086).
What are the official names of this protein?
Penicillin-binding protein 3, PBP 3, PSPB20, Penicillin-binding protein C.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Forespore inner membrane; Single-pass membrane protein. Forespore outer membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein. Note=Localizes at mid cell; localization requires FtsZ and PBP 2B (pbpB) (PubMed:28792086). Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion (PubMed:20713508, PubMed:22882210).
Protein: MURD_BACAN
Sequence: MKTVTEFQNKNILVLGIAKSGYAAATLLQKLGANVIVNDGKPLAENVLAAELQAKGMDVVCGGHPLELLERNISLVVKNPGIPYSNPILVAAKEKQIPIVTEVELAYRISEAPFVGITGSNGKTTTTMLTFEMLKEGQKHPVIAGNIGTVACEVAQDAKENEVVVTELSSFQLMGVELFQPKIAAFLNLFEAHLDYHGTKKEYGLAKANIFKNQTENDYSVINADDADVMALSAYSKGQKVLFSTTKEIEDGACIKDNALYFKAEKVVEVDDIVLPGQHNLENILAAMSIAKLLGVSNEAITAVLKRFTGVKHRLEYVTTINNRKFYNDSKATNMLATEKALSAFTQPTVLLAGGLDRGNEFDDLIPYFKNVKAIVTFGQTAPKLVRAAEKAGLDTIESVDTLDEAVVKAYAHSTDGDVILLSPACASWDQFKTFEERGDIFIQAVHKLI
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP062_YEAST
Sequence: MIELDYVKGEDTIVEATSTSPWLMRSPLARAAEKRGSGLFFDINEGHGQHRDVIVAYGVSKPKRRSPHPHGNKAADKRKTTEKEPERKKRVGAPRTCKKICIQLLYRFNFTVLGIGNVCNIDLLLGTVSATNAI
What are the official names of this protein?
Uncharacterized protein YPL062W.
Protein: KRBX4_HUMAN
Sequence: MAMSQESLTFKDVFVDFTLEEWQQLDSAQKNLYRDVMLENYSHLVSVGYLVAKPDVIFRLGPGEESWMADGGTPVRTCAGEDRPEVWQVDEQIDHYKESQDKLPWQAAFIGKETLKDESGQESRTCRKSIYLSTEFDSVRQRLPKYYSWEKAFKTSFKLSWSKWKLCKKER
What are the official names of this protein?
KRAB domain-containing protein 4, KRAB box domain-containing protein 4.
Protein: Y401_METMA
Sequence: MNKISKVVLVFIVILTIVILIKQSHEVKVAALFIQFENETTEPEVEAILENYDIPVNYTIDCNSNISRGKYYIKADEDKINELRKDENWTSVVELKKGNYNIIMLSAEFVPDENFLTVLEKNNLQLKKAVVCYIHFGNGSPDRVVGKNCVLEKDAIRIKNELEKNEKVLIVGLDYIQG
What are the official names of this protein?
UPF0228 protein MM_0401.
What is the protein family that this protein belongs to?
Belongs to the UPF0228 family.
Protein: CHEB_ECOL6
Sequence: MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAIDFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGERVLPGHAYIAPGDRHMELARSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAVGVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVSQQMLAKISAGQAIRI
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_METCA
Sequence: MAKHSQHSSPPRKLFDTLNDLWQRAKSEAGLSAEGPEGTRRRNNLILYLLLVLSTLYLLNGYQTLRNEEIPYSEFLKAVAEGRVEQAVVTEQTISGTLKPEAEGESTRPFITVPLWNHELAAELEKKGVKYTVRYGSNWFSSLIFNWIVPIVLLTLFWTWMARRMTGGRGFLSIGKKTRIQADTAAKVTFGDVAGADEAKQELRETIEFLQNPTRIQSLGGRMPKGVLLVGPPGTGKTLLARAVAGEAGVPFFNISGSEFIELFVGVGAARVRDLFEQARQNAPCIIFIDELDAIGRSRGGPVVMGGHDEREQTLNQLLTEMDGFDPSVGVAVMAATNRPEILDKALLRSGRFDRQIVVDKPGLEDRVSILKLHTRKMKLAADVDLRVVAQRTPGFVGADLANAANEAAIIAVRANKAAIGMADFEAAIDRILAGPEKKSRLLNDAEKHRVAVHESGHALVAEIVPTGQPVHKVSIIPRGAAALGFTLQLPVEEKFLSTEQELKDQIAILLGGRTAEELVFGESSSGAQNDLEKASEIARTMVCSLGMSKVLGPLTYGRRQQLAYLSVEGAEERNFSEETARLIDNEVRKLIEEGLQRVREILTHHRVTLDRLAALLREKEVVSGEDVKAVIREAAS
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: PURA_STAAC
Sequence: MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELDGLNERGIPTSNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLKSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTNVRTLEELPENARKYLERISELCNVQISIFSVGPDREQTNLLKELW
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTFA_ECO27
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVALAERFLQQKRLVPLQGFELNSLRSCRIALLFCLPVLKLGLEWLDGFHEVLIYPAPFVVDDEWEDDVGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFISLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_PHOPR
Sequence: MTLDISKYPHLALANTPDELRLLPVESLPEVCDELRTYLLNSVSQSSGHFASGLGAVELTVALHHVYNTPFDHLIWDVGHQAYPHKILTGRRDQMSTIRQKDGIHPFPWRGESEYDVLSVGHSSTSISAGLGMAIAANKEGLGRKVVSVIGDGAITAGMAFEAMNHAGDVHSDMLVILNDNEMSISENVGALNNHLARLLSGSLYTTIREGGKKVLAGAPPIKELVKRAEEHIKGMVVPGTMFEELGFNYIGPVDGHDVTELVKTLKNMRNLKGPQFLHIMTKKGKGYAPAEADPINYHAVPKFDLSQNPLPKAANAKPTFSKIFGDWLCDMAAEDEKLMAITPAMREGSGMVRFSKEYPSQYFDVAIAEQHAVTLASGMAIGGYNPIVAIYSTFLQRGYDQLIHDVAIMELPVMFAIDRGGLVGADGQTHQGAFDLSFMRCIPNIVIMAPSDENECRQMLYTGHKHQGPSAVRYPRGNGLGAEIQKEMTALEIGKGIIRRQGEKIAILNFGTMLEYALEAAEKLNATVADMRFVKPLDEELILELAANHDVLVTVEENAIAGGAGSGVIEFMMKSKCLKPVLNIGLPDRFVEQGTQQELHTALEIDAAGIEKKIRDYIA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: WDR13_MOUSE
Sequence: MAAVWQQVLAVDARYNAYRTPTFPQFRTQYIRRRSQLLRENAKAGHPPALRRQYLRLRGQLLGQRYGPLSEPGSARAYSNSIVRSSRTTLDRMEDFEDDPRALGARGHRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSVAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIREIPDPDGAELLCCTFQPVNNNLTVVGNAKHNVHVMNISTGKKVKGGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTKAKRLVVHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGALQLKRSFPIEQSSHPVRSIFCPLMSFRQGACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRREQK
What are the official names of this protein?
WD repeat-containing protein 13.
What are the subcellular locations of this protein?
Nucleus.
Protein: BPD_BP186
Sequence: MITGMTIDAGTSLAPAFMLTLNSQDITSNFSDRLISLTMTDNRGFEADQLDIELDDTDGKVELPLRGAVLTLWLGWQGSALLNKGDFTVDEIEHRGAPDILTIRARSADFRGTLNSRREESWHDTTIGELVSTIAKRNKLTASVADSLKKIPVPHIDQSQESDAVFLTRLADRNGATVSVKAGKLLFLKAGSAMTASGKPVPQMTLTRNDGDRHQFAIADRGAYTGVTAKWLHTKDPKPQKQKVTLKRKPKEKHLRALEHPKAKPVSKKTKAKKEPEAREGEYMAGEADNVLALTTVYASKAQAMRAAQAKWDKLQRGVAEFSITLALGRADLFPETPVRVSGFKRVIDEQAWLISKVTHNLNNSGFTTGLELEVKLSDVEYNAESDDE
What is the function of this protein?
Putative baseplate hub protein.
What are the official names of this protein?
Probable baseplate hub protein, Gene D protein, GpD, Late control gene D protein.
What is the protein family that this protein belongs to?
Belongs to the P2likevirus baseplate hub protein family.
What are the subcellular locations of this protein?
Virion.
Protein: KAD_RICPR
Sequence: MIVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTSTSEAELINNYVKQGALIPNEIVNQVIKVFLLSSKYKNGYILDGYPRNLEQAKFFEAFIQKPQIKIIYFDVADELLIKRVLGRYSCKNCGKIYNIHFLQPKIEHVCDVCSSSVFDYRKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIVNANKNEQEIENDIQKILKIN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_CLOBL
Sequence: MLNISIAIDGPAGAGKSTIAKIIGNKLNIMYINTGSMYRAVTLMALKNNIEPYDIESLKALINSMNISFNGNNIIVNGKDLEEDIRMPIINNNVSKYAAVEEVRELLVSMQQNISKKYNVVMDGRDIGTVVLKDAPYKFFITASAEVRAKRRLKELEEKGINISFQDVLKEIKERDYIDSNRKVNPLKQSKDAILIDTSNFTIEEVVDKICNIIKRD
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK4_ATRNU
Sequence: MAAAVDTFLFTSESVNEGHPDKLCDQISDAVLDACLAQDPESKVACETCTKTNLVMVFGEITTKANVDYEKIVRQTCRDIGFVSADVGLDADNCKVLVYIEQQSPDIAQGVHGHLTRRPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNENGAMVPIRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIARQAAKSIVAAGLARRCIVQISYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKETFDFRPGMIAINLDLLKGGSRYLKTAAYGHFGRDDADFTWETVKPLKWEKPQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate (By similarity).  May be involved in the synthesis of betain in response to abiotic stress such as high salinity (PubMed:15695433).
What are the official names of this protein?
S-adenosylmethionine synthase 4, AdoMet synthase 4, Methionine adenosyltransferase 4, MAT 4.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_LACSA
Sequence: MIFSTLEHIFTHISFSIVSIVIIIHLITLLGNEIIKPYDSSEKGMIVTFLCLTGLLITRWIYSGHFPLSDLYESLIFLSWSFSLIHIVPYFKIRKNYLTEITASSTIFTQGFATSGLLTEIRKPTILVPALQSEWLIMHVSMMILSYAALLCGSLLSVALLVITFRKIFYSYKSNNFLKLNESFSFGEIQYKNERNNILKKNYFLSAKNYYKAQLIQQLDYWSYRVISLGFIFLTIGILSGAVWANEAWGSYWSWDPKETWAFITWIVFAIYLHIRTNKNFQGANSAIVATLGFLIIWICYFGVNLLGIGLHSYGSFTLTSS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PAP1_FOWPN
Sequence: MERSRQVYYIINEYLGRHPSSTEYQVLKHQVEKISKINNFNKETFFFLLKKNKNKFFKDLELSDDLLKKRIDEYFSKQKHAKRLGNLFAIMELQKILISSFTKTIGILTTKVPEYYHSTIKLEYSSMEKIADDILDSYNVVEPSKEVKGRHKVSDLVGHVYKIMEEYLRRHSNSCLCYGSYSLHFLNNKIEYGDIDVLQTNARTFLINIAFLIKFITGRRIVLLKVPFLKNYVIMHDEETNHVMDTFNIREKTMNMIPKIMIDNMYIVDPCIQLLNMIKMLSQIDRLEELQAKFEKLSVRLGTLLEYTRYRYSIPLDSESILEVRAKLDKDKRKITVDFKKYKLNYIKCYFYLDEVELKKFISKNSGLDEYEDFEAVTNSEYAIRNKTMYTYFSNTALMRSENEIHPITINALTSHALLYHVITRKFYDDLLGDLVRSLMIVEKVPVFKIIPRDKKQGRHTIIDIEKDIIFH
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.
What are the official names of this protein?
Poly(A) polymerase catalytic subunit, Poly(A) polymerase large subunit, PAP-L, VP55.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family.
Protein: CATA_BRUME
Sequence: MTDRPIMTTSAGAPIPDNQNSLTAGERGPILMQDYQLIEKLSHQNRERIPERAVHAKGWGAYGTLTITGDISRYTKAKVLQPGAQTPMLARFSTVAGELGAADAERDVRGFALKFYTQEGNWDLVGNNTPVFFVRDPLKFPDFIHTQKRHPRTHLRSATAMWDFWSLSPESLHQVTILMSDRGLPTDVRHINGYGSHTYSFWNDAGERYWVKFHFKTMQGHKHWTNAEAEQVIGRTRESTQEDLFSAIENGEFPKWKVQVQIMPELDADKTPYNPFDLTKVWPHADYPPIDIGVMELNRNPENYFTEVENAAFSPSNIVPGIGFSPDKMLQARIFSYADAHRHRLGTHYESIPVNQPKCPVHHYHRDGQMNVYGGIKTGNPDAYYEPNSFNGPVEQPSAKEPPLCISGNADRYNHRIGNDDYSQPRALFNLFDAAQKQRLFSNIAAAMKGVPGFIVERQLGHFKLIHPEYEAGVRKALKDAHGYDANTIALNEKITAAE
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS7_DESVH
Sequence: MPRKGPVPRREILPDPLYNSRLVARFINRLMYDGKKGAAEKIFYSALDTLAQKTGEEPLKAFEKAIENVKPHLEVKARRVGGATYQVPMEVRPDRQVSLSLRWLIAYSRSRGEKGMVSKLSAELLDAFNNRGGAVKKKEDTHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SYGB_LISMF
Sequence: MSKDFLLEIGLEEMPAKYVTSSVLQLEKRVTDWLKDNQIEFKEIKTYSTPRRLTVLVEEMAEEQANRVEEAKGPAKKIALDDEGNWSKAALGFAKSQKVAPEDLTFREIKGVEYIYIKKEVIGEKTTALLPSLEKVVTSMTFPVSMHWGSNDLRYIRPIKWLIAMFGEEIIPFEITGVSTSNTSRGHRFLGKTATINQPSDYPNALLEQFVVVNASERKQAIVEQLRELETMENWQIREDDDLLEEVTNLVEYPTVLAGNFEKEYLELPEEVLITTMKEHQRYFPVFSQEGELLPHFVTVRNGNHENLDTVARGNEKVLRARLSDADFFYQEDLKITIDEAVAKLQNIVFHEKLGTLTEKMKRVQKVALMLADYLNWQEEDKQDIIRLTNIYKFDLVTNIVGEFPELQGLMGEKYALLQGEKPAIATAIREHYLPSSAEGDLPQTDLGSLIAIADKLETLIGFFCVNIAPTGSADPFGLRRSAFGAVRIIQANGWDIPMLEVVSRIVDMERAEGATELPSSDVIKEVQTFLKNRLRVILQGHHIRHDIIDAVIGGDPNMIPQLIDRAQILNKHADAEWFRPTIEALTRVVNISKKYEDGVEVDPSLFENEYEQALFDKLEKLKFDFAGLKIVDRLKAFADLRTTIDAYFDNTLVMTDNDELKNNRLALLFELASFIKEFAQMDEINVK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_ALBFT
Sequence: MSIFNKVTKTFQWGQNTVTMETGEIARQASGAVLLDMDGTVVLATVVAKTEGKAGQDFFPLTVDYLEKTYAAGKIPGSFFKREGRPSEFETLTSRLIDRPIRPLFPEGFFNEVHVVVHTLSLNPEVDADIAALIAVSAALSVSGIPFSGPIGAARVGYINGEYVLNPGQTARKDSVMDLVVAGTEAAVLMVESEAQQLSEEIMLGAVVFGHEQGNIAINAIHELVRDAGKPVWDWKAPAKDEPLIAKVGALAAHKLEAAYQIRNKQARTRACREAYAVVMADLKLDGVAFDSVAVEGMLFDIEAKIVRSQILAGEPRIDGRDTRTVRPIEIRNSVLPRTHGSALFTRGETQALVVTTLGTERDAQRIDALSGDYEDRFMLHYNMPPFATGETGRVGTPKRREIGHGRLAKRALMAVLPSKEEFPYTMRVVSEITESNGSSSMASVCGGCLSLMDAGVPMKAHVAGIAMGLIKEENRFAVLTDILGDEDHLGDMDFKVAGTTNGITALQMDIKIQGITKEIMQVALAQAKEARMHILGKMQEAMAEAKTEVSTFAPRLFTMKINPDKIRDVIGKGGSVIRALTEETGTQINIDEDGTITIASADPAKAEEAKRRIQQITAEVEIGKIYEGPITKILDFGALVNLLPGKDGLLHISQIAHERVEKVTDYLSEGQIVKVKVMETDEKGRIKLSMKVLLDRPGQGGPEHV
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_GLOVI
Sequence: MMQPYLRPDLDRLQAYHAPHFPEADKLDANELPHDLPEWLKNKLAFLLEQGVRTNRYPEGDPLALKAAIAEYCGVTSEMVCVGNGSDELIRSLITATCLGGRGTVASAEPTFSMYRILAETLAVPYIGVARTANYGVDADVLEAAVGANGVRVLFLANPNSPTGNLLSDEIIERLGSLPVLVVLDEAYYEFSRFSAVPLLWERPNLVILRTFSKAFRLANFRVGYALANPEIAAVLEKVRLPYNLPGLSQLAAFAALEHRDVLLAAIPEILAERRRIERFLADFEQLELFPSDANFLFVRPRIADPEAVRVALAGRGSLVRGAAGGLRVTVGTPEQNDRLIANVAALFTPEMR
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: HELQ_HUMAN
Sequence: MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLPVEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFIAQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGAVASSTDKA
What is the function of this protein?
Single-stranded 3'-5' DNA helicase that plays a key role in homology-driven double-strand break (DSB) repair (PubMed:11751861, PubMed:19995904, PubMed:21398521, PubMed:24005041, PubMed:24005565, PubMed:34316696, PubMed:34937945).  Involved in different DSB repair mechanisms that are guided by annealing of extensive stretches of complementary bases at break ends, such as microhomology-mediated end-joining (MMEJ), single-strand annealing (SSA) or synthesis-dependent strand annealing (SDSA) (PubMed:34937945).  Possesses both DNA unwinding and annealing activities (PubMed:34937945).  Forms a complex with RAD51, stimulating HELQ DNA helicase activity and ability to unwing DNA (PubMed:34937945).  Efficiently unwinds substrates containing 3' overhangs or a D-loop (PubMed:21398521, PubMed:34937945).  In contrast, interaction with the replication protein A (RPA/RP-A) complex inhibits DNA unwinding by HELQ but strongly stimulates DNA strand annealing (PubMed:34937945).  Triggers displacement of RPA from single-stranded DNA to facilitate annealing of complementary sequences (PubMed:34316696, PubMed:34937945).
What are the official names of this protein?
Helicase POLQ-like, Mus308-like helicase, POLQ-like helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to sites of DNA damage; localizes to damaged replication forks.
Protein: BASS3_ORYSJ
Sequence: MAAAVAASSSSSSSSCAAVGVATASHPHRHRQARFVVSPPAPASPAALLWRRPRRVAPTTFCSAPSLGRVGWPRREGAAWLLSFRAGPVSSPSSAAAGDPSQALSALLPLVVAATAVAALGNPATFSWVSKEYYAPALGGIMLSIGIKLSIDDFALAFKRPVPLTIGYMAQYIVKPLMGVLIARAFGMPSAFFAGFVLTCCVSGAQLSSYASFLSKGDVALSILLTSCSTISSVVVTPVLTGLLIGSVVPVDGIAMAKSILQVVLVPVTLGLLLNTYAKAVVNVIQPVMPFVAMLCTSLCIGSPLAINRSKILSSEGFLLLLPIVTFHIAAFIVGYWISKLPMLRQEEPVCRTISVCTGMQSSTLAGLLATQFLGSSQAVPAACSVVIMAIFGLTLASYWGNGLRIRDIGSRFVPQASAGVSS
What is the function of this protein?
May function as sodium-coupled metabolite transporter across the chloroplast envelope.
What are the official names of this protein?
Probable sodium/metabolite cotransporter BASS3, chloroplastic, Bile acid-sodium symporter family protein 3.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Protein: HBEAG_HPBDC
Sequence: MWNLRITPLSFGAACQGIFTSTLLLSSLTVPLVCTIVYDSCLYMDINASRALANVYDLPDDFFPKIDDLVRDAKDALEPYWKSDSIKKHVLIATHFVDLIEDFWQTTQGMHEIAESLRAVIPPTTAPVPTGYLIQHEEAEEIPLGDLFKHQEERIVSFQPDYPITARIHAHLKAYAKINEESLDRARRLLWWHYNCLLWGEANVTNYISRLRTWLSTPEKYRGRDAPTIEAITRPIQVAQGGRKTSSGTRKPRGLEPRRRKVKTTVVYGRRRSKSRERRAPSPQRAGSPLPRSSSSHHRSPSPRK
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted.