PharMolix/UniProtQA huggingface dataset:
Protein: IF1_SALPA
Sequence: MAKEDNIEMQGTVLETLPNTMFRVELENGHMVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_STAAN
Sequence: MATKNEEILRKPDWLKIKLNTNENYTGLKKMMREKNLNTVCEEAKCPNIHECWGARRTATFMILGAVCTRACRFCAVKTGLPNELDLNEPERVAESVELMNLKHVVITAVARDDLRDAGSNVYAETVRKVRERNPFTTIEILPSDMGGDYDALETLMASRPDILNHNIETVRRLTPRVRARATYDRTLEFLRRSKELQPDIPTKSSIMVGLGETIEEIYETMDDLRANDVDILTIGQYLQPSRKHLKVQKYYTPLEFGKLRKVAMDKGFKHCQAGPLVRSSYHADEQVNEAAKEKQRQGEAQLNS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEGS_ECOLU
Sequence: MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKGDAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATSVRIPEALDKALKLAIAGDAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALGGVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALINDGLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQNFHIEILPAALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_MYCBO
Sequence: MVQPADIDVPETPARPVLVVDFGAQYAQLIARRVREARVFSEVIPHTASIEEIRARQPVALVLSGGPASVYADGAPKLDPALLDLGVPVLGICYGFQAMAQALGGIVAHTGTREYGRTELKVLGGKLHSDLPEVQPVWMSHGDAVTAAPDGFDVVASSAGAPVAAFEAFDRRLAGVQYHPEVMHTPHGQQVLSRFLHDFAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAVAAALVQRAIGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSGVSAPEGKRKIIGRQFIRAFEGAVRDVLDGKTAEFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGLPEEIVARQPFPGPGLGIRIVGEVTAKRLDTLRHADSIVREELTAAGLDNQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYEVLERISTRITNEVAEVNRVVLDITSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RIMP_BART1
Sequence: MNEAEKISNLDEPRLFEEDGIEARVAALVIPLLKPLGFRLVRVKLLGQNGLTLQIMVERADGSLTVEDCETVSRTVSPLLDVENVIERKYHLEISSPGIDRPLVRKSDFFHWQGHLAKIETKITIDGRRKFRGTLTNITQDGFILNADKAAYGEAMYTSISFCDIIGAHLVLTDELIRDALKKNKDLSQQFIPEDNPTDSIQTLNFKK
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_LISMF
Sequence: MIVIIDYDTGNTKSISKALDFIGLQNKISSDKTEIAQADGVILPGVGAYPEAMQELTRRGLDKTLKEIATAGKPILGVCLGMQLLLESSNEHSYTKGLGLIPGHVEMLPDESEFAVPHMGWNQLQIKRTTPLTQNIAGEYVYYVHSYYANCPEAYIIATSGYSIDIPGMINNGNIYGAQFHPEKSGQIGLEILKGFKEVIRSCKSSQQ
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QWRF2_ARATH
Sequence: MVAAAISTTDPRNPPRDRPQSLTNNGGQRRPRGKQVPSRYLSPSPSHSVSSTTTTTTTTTTTTSSSSSSSSSAILRTSKRYPSPSPLLSRSTTNSASNSIKTPSLLPKRSQSVDRRRPSAVSVTVGTEMSAATKMLITSTRSLSVSFQGEAFSLPISKKKETTSTPVSHRKSTPERRRSTPVRDQRENSKPVDQQRWPGASRRGNSESVVPNSLSRSLDCGSDRGKLGSGFVGRSMLHNSMIDESPRVSVNGRLSLDLGGRDEYLDIGDDIQRRPNNGLTSSVSCDFTASDTDSVSSGSTNGVQECGSGVNGEISKSKSLPRNIMASARFWQETNSRLRRLQDPGSPLSSSPGLKTSSISSKFGLSKRFSSDAVPLSSPRGMASPVRGSAIRSASPSKLWATTTSSPARALSSPSRARNGVSDQMNAYNRNNTPSILSFSADIRRGKIGEDRVMDAHLLRLLYNRDLQWRFVNARADSTVMVQRLNAEKNLWNAWVSISELRHSVTLKRIKLLLLRQKLKLASILRGQMGFLEEWSLLDRDHSSSLSGATESLKASTLRLPIVGKTVVDIQDLKHAVSSAVDVMQAMSSSIFSLTSKVDEMNSVMVETVNVTAKEKVLLERCQGCLSRVAAMQVTDCSMKTHIIQLSRIPITSSLTPQL
What are the official names of this protein?
QWRF motif-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the QWRF family.
Protein: RS9_SYNWW
Sequence: MAKVQYWGTGRRKEAVARVRLVPGEGNIIINNRSFEDFFPNQTSRLIVQQPLVLTAMQGRFDIICRVNGGGVSGQAGAIQLGIARALLKANPDIKAMLRRSGFLTRDPRMKERKKYGLHKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: XLNR_ASPFU
Sequence: MSTTSLQHFPHSYSPFSSSRSLNRMAQSQTSGLDTLAEGSQYALEQLQMSREAAGSGEATDSVGKPKDQFQVDNDNHHNNHSLSNFKNPSQRDPLVEARSTIRKNSASAPVRRRISRACDQCNQLRTKCDGQNPCAHCIDFGLTCEYARERKKRGKASKKDLAAAAAAAAAAATNSGQPNGSSGKEDAALVGGHTSPDRRPTINGRYDPAFEVPRNLNGSAQHSEASGMVGMQNSQHLPPHSQSSMGGGLEGLPLNGYNGLNDSGRPSMPVPELQSLHMLHNSHTNPRSPSSILPHHRYNGGYNDSAYSLMNPQEPNSTSISHFRLGSSTENPPNSFLGLSPPAQSPGWLPLPSPSPANFPSFSMASFSTTLRYPVLHPVLPHIASIIPQSLACDLLDVYFTSSSSSHLSPQSPYVVGYIFRKQSFLHPTKPRVCTPGLLASMLWVAAQTSDAPFLTSPPSARGRVCQKLLELTIGLLRPLIHGPAPGETSPNYAANMVINGVALGGFGVSMDQLGAQSSATGAVDDVATYVHLATVISASEYKAASMRWWTAAWSLARELKLGRELPPNTPHARPDAERDGDPDADLSKRHPPPLITSMGHGPGNTIINITEEEREERRRLWWLLYATDRHLALCYNRPLTLLDKECEGLLQPMNDDLWQAGDFATYRQAGPPVECTGHSMFGYFLPLMTILGEIVDLQQARNHPRFGLAFRNSAECEAQVLEIARQLDVYAQSLKEFETRYTSSLALGAAETEAAMDGSHPNHVSPSGRSSSTVESRVNESIVHTKMVVAYGTHIMHVLHILLAGKWDPINLLDDNDLWISSESFVAAMGHAVGAAEAAAEILEYDPDLSFMPFFFGIYLLQGSFLLLLTADKLQGDASPSVVRACETIVRAHEACVVTLNTEYQRTFRKVMRSALAQVRGRLPEDFGEQQQRRREVLALYRWTGDGSGLAL
What is the function of this protein?
Transcriptional activator of the xylanolytic system.  Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose (By similarity).
What are the official names of this protein?
Xylanolytic transcriptional activator xlnR, Xylanase regulator.
What is the protein family that this protein belongs to?
Belongs to the xlnR/xlr1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMM_SHESW
Sequence: MKNLFLFCRAGFEKECAAEIQQRAGELNVGGFVKANNNDAYVVYQCFEDDAADTLVKQLPLDSLIFARQMFAASDLLVDLPENDRISPIVAALSDVSKAGEVRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYVGYSYSNNSSPHFMGIPRLKMAADAPSRSSLKLDEAFGQFVPKEEQEERIRSGMNAVDLGACPGGWTYQLVRRGMFVSAVDNGPMDEKLMETGQVKHYREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVTAILETMQTILKENGVTDFKVQCKHLYHDRDEVTVHLWLRPNTAWN
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_YERPG
Sequence: MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGPGFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQVAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLGADRILYYIDSRQHQHLMQAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVERAGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDETSLTLPLVVTEDREATLATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKTLKQGLDTLGIQTVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_MYCS2
Sequence: MTGISLPPELQRVHMVGIGGAGMSGVARILLDRGGLVSGSDAKESRGVVALRARGAEIRIGHDASSLDLLPGGPTAVVTTHAAIPKTNPELVEARKRGIPVILRPVVLAKLMTGYTTLMVTGTHGKTTTTSMLIVALQHSGFDPSFAVGGELGEAGTNAHHGSGTTFVAEADESDGSLLEYTPNVAVVTNIEADHLDFFGSEQAYTAVFDSFVERIAPGGALVVCTDDPGAAALADRTDALGIRVLRYGSTGDNLAGTLLSWEQQGTGAVAHIRLAGEHNPRAVRLSVPGRHMALNALAALLAAREIGAPTDSVLDGLAGFEGVRRRFELVGTAAGARVFDDYAHHPTEVRATLEAARTVVDQNGGRVVVAFQPHLYSRTATFAHEFGAALSVADQVVVLDVYAAREQPMAGVSGATVADHVTAPVTYVPDFSAVAAHVASIARSGDVILTMGAGDVTMLGGEILSELRLKDNRGMPGAGAS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2558_PSET1
Sequence: MITVISPAKNLDYTTPPATDKFTQPELLEHSEALMQVCRELTPAQIGSLMKISDKLSGLNAARFSEWAQPFTTENAKQAVLAFNGDVYGGLDASTLTANQLDYAQSHLRILSGLYGLLKPLDLMQAYRLEMGTKLENSRGKNLYEFWGSVIANKLNEVLKAEDAQYLVNLASNEYFKAVDKKALNAQIITPHFKDCKNGQYKVISFYAKKARGMMARYLIENKVTQLSQLKEFTVAGYYFSAEASVKELEPVFLRDEQS
What are the official names of this protein?
UPF0246 protein PSHAa2558.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: S22AR_MOUSE
Sequence: MSFQELLNQVGSLGRFQILQIVFLLLLNAIVVPHIAMENFTAAIPNHRCWVPILDNDTASDNGSRILSQDDLLRISIPLDSNLRPEKCRRFAQPQWHLLHLNGTFSNVSEPDTEPCVDGWVYDRSNFLSTIVTEWDLVCESQALNSVTKFSFMIGLFIGGIICGHLSDRLGRKFILTCALLQFAITETCVAFAPSFFIYCSLRFLAGLSVEPILVNSHLLMLEWTSPKFLTMMAALLSCAPNIGYMISAGLAFLFRIWHHLQLTMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGDLTMEIVRTSMKAELEAAKTKPSLRDLFHTSILRKRICVLSFMRLFFTVSIFGLAVHLQHLSSNIILLQFLISALAILVSVIGPFVLNHIGRRITYLVLMSLRGIFILIAVFVPQEMQTLRIIMATLAEGISSLCVGVSRLHTNELLPTTLRATAVGVIGFFGNSGSFLSPLFMLLATYYANMPWIFYGGFSIFNAFTVFLLPETKNQPLPDSTHDVGNDWKESRKGKKEDPIIKVTRF
What is the function of this protein?
Sodium-independent organic anion transporter which exhibits high specificity for L-carnitine.  Can also transport salicylic acid and the drug cimetidine.
What are the official names of this protein?
Solute carrier family 22 member 27, Organic anion transporter 9.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DADA_CERS4
Sequence: MRIVVLGAGVVGVTSAYELARAGHEVTVVDRQPAAALETSFANAGEISPGYASPWAAPGIPAKALRWMFMKHAPLVIRPRLDAAQVRFLLAILRNCTPAAYAQNKGRMVRLAEYSRDCLTDLRATTGLAFDERQQGTLQLFRSQKQLDAAARDIEVLRAGGVPFELLDADGCLAAEPGLRAARDRIAGGLRLTGDETGDCFKFTQGLAGLAEEGGVRFRYGTGVERLRVEGGRVTGVETTKGTFLADAVVVALGSHSPALVAPLGLRLPVYPVKGYSITVPIVDADRAPVSTVMDETYKIAITRLGTRIRVGGMAEVAGFSATLPPARRETLAMSVNDLFGGAGDLSRASFWTGLRPMTPDGTPVVGRTPVAGLWLNTGHGTLGWTMAAGSARVLSDLIDGRAPEIESADLGIERYAAPGRRARPAVRLNPARQAG
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: FOLD_NITSB
Sequence: MQILDGKKLSQKIKESIKKEVEELKKEQDIIPGLAVILVGDDPASHTYVKMKARACKDVGIYSIVHEMPESISQKEIEETISMMNKNPNIDGILVQLPLPKHIDTTKILELIDPAKDVDGFHPYNFGRLMQGLDTFAPCTPLGVMELLDEYGIDVKGMNACVVGASNIVGKPMAALLLNRFATVDICHIYTKDLAEHTKKADIIAVGVGKPNLITADMVKERAIVIDIGINKVGNKIVGDVDFENVSKKASYITPVPGGVGPMTIAMLLKNTIKAAKQRKRS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL7A1_ARATH
Sequence: MAPKKGVKVAAKKKTAEKVSNPLFERRPKQFGIGGALPPKKDLSRYIKWPKSIRLQRQKRILKQRLKVPPALNQFTKTLDKNLATSLFKVLLKYRPEDKAAKKERLVKKAQAEAEGKPSESKKPIVVKYGLNHVTYLIEQNKAQLVVIAHDVDPIELVVWLPALCRKMEVPYCIVKGKSRLGAVVHQKTASCLCLTTVKNEDKLEFSKILEAIKANFNDKYEEYRKKWGGGIMGSKSQAKTKAKERVIAKEAAQRMN
What are the official names of this protein?
60S ribosomal protein L7a-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: IGA1_HAEIF
Sequence: MLNKKFKLNFIALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDLGTALPNGIPMIDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVSSEENRYFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYNDQNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYKVNHENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFWAGYNKKSWQEWNIYKSQFTKDVLNKDSAGSLIGSKTDYSWSSNGKTSTITGGEKSLNVDLADGKDKPNHGKSVTFEGSGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVAEGKTVTWKVHNPQYDRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQHAFASVGIVSGRSTLVLNDDKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGARLVNHNMTNASNITITGESLITDPNTITPYNIDAPDEDNPYAFRRIKDGGQLYLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNLNGDLTVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTGNASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKALNSFNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADNSNNVTKYNTLTVNSLSGNGSFYYLTDLSNKQGDKVVVTKSATGNFTLQVADKTGEPNHNELTLFDASKAQRDHLNVSLVGNTVDLGAWKYKLRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNTSMNKNYSSSQYRRFSSKSTQTQLGWDQTISNNVQLGGVFTYVRNSNNFDKATSKNTLAQVNFYSKYYADNHWYLGIDLGYGKFQSKLQTNHNAKFARHTAQFGLTAGKAFNLGNFGITPIVGVRYSYLSNADFALDQARIKVNPISVKTAFAQVDLSYTYHLGEFSVTPILSARYDANQGSGKINVNGYDFAYNVENQQQYNAGLKLKYHNVKLSLIGGLTKAKQAEKQKTAELKLSFSF
What is the function of this protein?
Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.
What are the official names of this protein?
Immunoglobulin A1 protease autotransporter.
What are the subcellular locations of this protein?
[Immunoglobulin A1 protease autotransporter]: Periplasm. SUBCELLULAR LOCATION: [Immunoglobulin A1 protease]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Immunoglobulin A1 protease translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: NDD_BPT6
Sequence: MKYMTVTDLNNAGATVIGTIKGGEWFLGTPHKDILSKPGFYFLVSKLGGPFSSPCVSARFYVGNQRSKQGFSAVLSHIRQRRSQLARTIANNNVPYTVFYLPASKMKPLTTGFGKGQLALAFTRNHHSEYQTLEEMNRMLADNFKFVLQAY
What is the function of this protein?
Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation.  Only the architecture of the nucleoid is affected.  May act on the host chromosomal sequences that determine the structure of the nucleoid.  Binds to dsDNA but not to ssDNA.
What are the official names of this protein?
Nucleoid disruption protein, Nuclear disruption protein.
Protein: FZD1_RAT
Sequence: MAEEAVPSESRAAGRPSLELCAVALPGRREEVGHQDTAGHRRPRAHSRCWARGLLLLLWLLEAPLLLGVRAQPAGQVSGPGQQRPPPPQPQQGGQQYNGERGISIPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERAQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGYRGGYPGGAGPVERGKFSCPRALRVPSYLNYHFLGEKDCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQGGGGVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
What is the function of this protein?
Receptor for Wnt proteins.  Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6 or WNT7A.  Contradictory results have been reported for activation by WNT7B.  Functions in the canonical Wnt/beta-catenin signaling pathway.  The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity).  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
What are the official names of this protein?
Frizzled-1, Fz-1, rFz1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPD_AZOVD
Sequence: MDIKQALARVAERLDLNTAEMQGVMRQIMTGQCSDAQIGAFLMGMRMKSESIDEIVGAALVMRELAAPVTIGVERLVDTCGTGGDGMNIFNVSTAAAFVVAAAGGRVAKHGNRAVSGKSGSADLLEAAGVYLELSPEQVARCVESVGVGFMFAPAHHGAMKHAIGPRRELGLRTLFNMLGPMTNPAGVKRQVLGVFSQALCRPLAEVMARLGSVHVLVVHAQDGLDEISLAAPTHIAELRNGEISEYLVQPEDFGIKSQSLIGLDIEGPQESLALIRDALGRRKTEHGQKAAEMIVLNAGAALYAADQAGSLKEGVALAHDALHTGLARDKLEELASITAVFRQENQA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: YL754_MIMIV
Sequence: MIPMTIVQKMILMEIVQKMILITIIQKMNQIANYTMKKIINAPGIIKLTKKEKIKDNDGNIIEIEVRGTRDPENIFFRVSDVINGFDMPKLYDTITRNNSGYRQNIHYRYFNFKKTTKKGYCMKLFLTFIGMEKVINCSRSIHIQNAMIARKWLSQFSASIKFNSLVLDSSKSSTSNIGYVYCITSEKIDANKIGYWKGTRKDLICRYKTYYGDYVELFCVKTMYPELLEKKCHQHFINYKLSHELYDKSNTDKYKLYLKENKITPTEQDIYEDQQITKTDVKTLFTTHLTTQDQKNKLSSKLMGIPTNIISVDKIKELENEIKELKYQNEIKELKYQNEIKELKYQNEINELKYKNIILEKDLEISNLNKKLKKKN
What are the official names of this protein?
Uncharacterized protein L754.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L5 family.
Protein: ECFA2_ACET2
Sequence: MSIKVTGLTYVYMKGTPYEKKALDNINLSIETGEFVGIIGHTGSGKSTLVQHFNGLLKPTSGSVYINGEELTGQRAKELKKQVGIVFQYPEHQLFEETVYKDIAFGLVRRGEEKDEIYRKVRKTIRLVGLSEDILDKSPFELSGGQKRRVAMAGILVLEPSILVLDEPAAGLDPKGREEIFELVSNLHKNNKMTVILVSHSMEDVAKYVQRVIVMNQGRIEMCGPVRSVFKNTETLEEIGLAAPQITYLMKKLKEKIPQINDDILTIAEAKEELAKYIRKA
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SL1_ECHOC
Sequence: MGRFIFVSFGLLVMFLSLSGTEAGVCCPFGWSGYDQNCYKAFEELMTWADAEKFCTQQHKGSHLLSLHNIAEADFVVKTTVSGLKDGVIWMGLSDVWNECNWGWTDGAQLDYKAWNVASNCFIFKTAENHWSRTDCSGTHNFVCKSPA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 1, C-type lectin 1, CTL-1.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASSY_ERYLH
Sequence: MPDIKRVVLAYSGGLDTSVIAKWLEVERGLEVVTFTADLGQGEELEPARAKAQAMGIPDKHIFIEDLREEFVRDYVFPMMRANARYEGDYLLGTSIARPLISKRLVEIAQETGADAIAHGATGKGNDQVRFELSAYALDPDIKVIAPWREWDLTSRTALIAWAEKHQIQVPKDKRGESPFSTDANLLHTSSEGKVLEDPWEETPDYVYSRTVNPEDAPDEPEFITIDFERGDGIALNGEAMSPANLLTALNELGRKHGIGRLDLVENRFVGMKSRGMYETPGGEIYARAHRGIEQITLDRGAAHLKDELMPKYAELIYNGFWFSPEREMLQAAIDLSQDKVSGTVRLKLYKGNADVVGRKSPNSLYSEAHVTFEDDAGAYDQSDAEGFIRLNALRLKLLGKRDR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP6B_METAC
Sequence: MEIPIAEELAKKQKSISVAEFFEKNRQILGFDSAPRSLITTVKEAVDNSLDACEEAGILPDILVQVERTGQDYVTVIIEDNGPGIVREQIPKVFAKLLYGSRFHALKQSRGQQGIGISAAVLYAQMTAGRHTKILSKTGSNVPAHYYELMINTSTNEPDILMDEVRDWFRPHGTQIELEMKAAYVKGRRQSIYEYLKATAIVNPHARITLIDPDGNEEVFERATDKIPDPAEEILPHPEGIELGTLMKMLHYTERQKLAPFLRYSFCKIGLLTADEICKAAGLDPEIDPHALGRHEARKLIEAFQKVKIMSPPTDCLSPIGEELIYRGLEKETNVDFIATSTRKPAVYSGNPFVVEVGLAYGGNLPKEEKISIMRFANRVPLLYQQGGCVTTHAVEDIRWKQYGLNQPGGGVPIGPVLLLIHVASINVPFTSESKDAIADIPVIKEEVDLAVKEVARKLKHYLSKQSNLKKRREKEIIITKVLPKMAVKVANILEKDVPDINPVVAKIMGNLLVYRKVKSNGDGTADVAIKVKNFGTSAHSFRVHEMLPCKINGAKPEPKVVTMDNDYDYVWDVSAAAGSSKVLSYKIESATVEELRKLPQLIVEGIEEELVTGAKAFRGV
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: FLGH_ECODH
Sequence: MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.