PharMolix/UniProtQA huggingface dataset:
Protein: RS16_METCA
Sequence: MVSIRLARGGAKKRPFYHVVVAESRSKRDGRYIERVGFFNPIARGQEERLRLDESRIAYWIGTGAKPSDRVVSLIKEFKKQQQV
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MDH_RHIWR
Sequence: MARTKIALIGAGNIGGTLAHLAASKELGDVVLFDVVEGVPQGKALDLSQCGPVEGFDAKLKGTNDYADIAGADVIIVTAGVARKPGMSRDDLLGINLKVMKSVGEGIKANAPDAFVICITNPLDAMVWALREFSGLPHNKVVGMAGVLDSARFATFLAEEFNVSVQDVTTFVLGGHGDTMVPVVEYSTVAGIPIPDLIKMGWSTQERIDAIVQRTRSGGGEIVALLKTGSAFYAPATSAIAMAESYLKDKKRVLPCAAYLSGEYGVDDLYVGVPVIIGANGVEKIVEINLSDSAKANLQVSVDAVKELLVACKGIDSSLA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: KU70_YARLI
Sequence: MEWISHLENDDDVLEIEDYKVRKDALLIAIQVTQNAINNGTLHKALEAAFDAVTDRIVISPQDYTGVMLFGASMQSEDDGDEFDDESDTHFILKLGLPTAAQIKRLKRLAEDPDLGERFKVQEEPHLMDVFFDMNRHFINMAPNFASRRIIYITDDDTPTTNEDDINKTRVRIEDLSHLKVKVEPLLINPSEDKTFDSSKFYALVFNEDTSVEPVEAIDLKQFINKRNVLNRSLFNVKMEIGEGLVVGVRGYLLYAEQKATSTTRKAWVYTGGEKPEIAKLESQAVTIESGRSVDKADLRKTFKFGNDYVPFTEEQLTQIRYFGEPIIRILGFHNSSDFSELFIHSVRSSMFLYPTDEKLVGSIRAFSALYQSLKNKDKMALAWVIVRKGAKPILALLIPSTKEIEGLHMVFLPFTDDIRQEPKTELVSAAPELVDATKNIFTRLRMPGGFESQRYPNPRLQWHYRVVRAMALQEEVPKVPEDKTTPKYRSIDTRVGDAIEEWNKVLQSSSKRPAEDICKAEKKVKSSDAGPPSNEQMQNMVENDIVGKLTVAELRAWGAANNVEPNGSKLKKDWVEVVKKYYGK
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit Ku70.
What is the protein family that this protein belongs to?
Belongs to the ku70 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: PYRH_PARL1
Sequence: MSDKPLYSRVLLKVSGEALMGPAQYGIDLDTVDRVARDIKQAIDAGVQVCLVIGGGNIFRGLSGAAKGMERASADYMGMLATVMNALAMQTALEAIGVPTRVQSAIPMMTVCEPYIRRRAVRHMEKGRVVIFAAGTGNPFFTTDTAAALRAVEMGCDALLKGTQVDGVYSADPHKVANAERYDRLTYMDVLARDLKVMDASAIALARENAIPIIVYSIDEPGGFAEVLTGAGRCTIISDAA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGMG3_BURCH
Sequence: MAMPRNLPGQAAHDEADQEILRLDGIRKRFPGVLALDGIRLDLRRGEVHAVCGENGAGKSTLMKIISGQYLPDEGAVHYRGAPVRFRSASEAQAAGISIIHQELNLVPHLSVAENLFLAREPRRGPFVDTKRMNAEAARCIARIGLNVAPTTKVGVLSIAQQQMVEIAKALSHDARVLIMDEPTSSLTEAETVQLFRIIEELRADGVAILYISHRLDEMAQIVDRVTVLRDGRHISTDDFADVSIDDIVARMVGRTLDDAYPSRQSVPTDDVLLDVRDLRRDGVFGPVSFALRRGEILGFAGLMGAGRTEIARAIFGADRPDGGTIALHGRPVTIRSPREAIRHGIAYLSEDRKKEGLALPMPVAANLTLANVRGIASRFGFLRFDDEIDVARRYVQDLAIRTPSVHQRVRNLSGGNQQKVVIGKWLYRGSKILFFDEPTRGIDVGAKFAIYGLMDRLAADGVGVVLISSELPELLGMTDRIAVFHEGRMTAILDTKHTSQEEIMHYASGRSHA
What is the function of this protein?
Part of an ABC transporter complex involved in carbohydrate import.  Could be involved in ribose, galactose and/or methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Putative ribose/galactose/methyl galactoside import ATP-binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NU6M_BRACM
Sequence: MILSVLSSPALVSGLMVARAKNPVHSVLFPIPVFRDTSGLLLLLGLDFFAMIFPVVHIGAIAVSFLFVVMMFHIQIAEIHEEVLRYLPVSGIIGLIFWWEMFFILDNESIPLLPTQRNTTSLRYTVYAGKVRSWTNLETLGNLLYTYYSVWFLVPSLILLVAMIGAIVLTMHRTTKVKRQDVFRRNAIDFRRTIMRRTTDPLTIY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: BLC2_SALTM
Sequence: MMTQSIRRSMLTVMATLPLLFSSATLHAQANSVQQQLEALEKSSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKQSESDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGPDKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRAQLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQPEQKAESRRDILAAAAKIVTHGF
What is the function of this protein?
Has cefotaxime-hydrolyzing activity.
What are the official names of this protein?
Beta-lactamase CTX-M-2, Cefotaximase 2.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: ATPL_STRPN
Sequence: MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLMFLGVAFIEGTFFVTLVFSFIIK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURQ_BACP2
Sequence: MKFAVIVLPGSNCDIDMYHAIQDELGEQVEYVWHDETSLDGFDGVLVPGGFSYGDYLRCGAIARFSNIMPAVKKAAAEGKPVLGVCNGFQILQELGILPGAMRRNKDLKFICRPVELIVENNETQFTSGYQKGESISVPVAHGEGNFYCDEDTLAKLIENNQIAFTYGDDINGSVNRIAGITNEEGNVLGMMPHPERAVDSLLGSADGLKLFQSIVKNWRDTHVTTA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADB_PHOLL
Sequence: MLYQSETIQVSWLKDGIAELVFNAPAAINKLDTKTVASLDKAIASLEQQTGLKGVLLRSEKTAFIVGADITEFLSLFDSPVEKLQEWLNFSNSIFNRIEDLPVPTISAINGYALGGGCECVLSTDFRVASPDIRIGLPETKLGIMPGFGGSVRLPRLIGTDNALDIIAAGKDIGAEEALKNGLIDAVVPKEKLVDSAVSMLEQAIAGNLDWKAARQPKLEPLKLNETERGMSFSVAKGMVMKVAGPHYPAPITAVKSIEKAATFGRDEALKQETASFIPLAQTNVARALVGIFLNDQYVKGLAKKHLKEVTIPEYAAVLGAGIMGGGIAYQSARKGIPVMMKDISQQSLELGMNEAAKLLNKQFERGRLDAIKMARTLSSIQPTLNYAGIEQAQIVVEAVVENPKIKAAVLSETETLVNEDCVLASNTSTIPISELAKSLKRPENFCGMHFFNPVHRMPLVEVIRGEKTSEKTISTVVAYASKMGKTPIVVNDCPGFFVNRVLLPYLLGFGLLLRDGGDFRQIDKIMEKEFGWPMGPAYLIDVIGLDTAHHSQSVMAQGFPDRMHRDYKDAIHVLYDNQRYGQKNGLGFYKYTQDKKGKPKKEQDEQTDQLLATICQQKSNFSGEEIIARTMIPMINEVVRCLEEGVIASPAEADMALVYGLGFPPFHGGVFRYLETMGTAAYVKMAENYAHLGALYQVPPGLKAKAERNESYYSTAATIAVSTGKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: F6CGT_GENTR
Sequence: MGSLTNNDNLHIFLVCFIGQGVVNPMLRLGKAFASKGLLVTLSAPEIVGTEIRKANNLNDDQPIKVGSGMIRFEFFDDGWESVNGSKPFDVWVYINHLDQTGRQKLPIMLKKHEETGTPVSCLILNPLVPWVADVADSLQIPCATLWVQSCASFSAYYHYHHGLVPFPTESEPEIDVQLPGMPLLKYDEVPDYLHPRTPYPFFGTNILGQFKNLSKNFCILMDTFYELEHEIIDNMCKLCPIKPIGPLFKIPKDPSSNGITGNFMKVDDCKEWLDSRPTSTVVYVSVGSVVYLKQEQVTEMAYGILNSEVSFLWVLRPPSKRIGTEPHVLPEEFWEKAGDRGKVVQWSPQEQVLAHPATVGFLTHCGWNSTQEAISSGVPVITFPQFGDQVTNAKFLVEEFKVGVRLGRGELENRIITRDEVERALREITSGPKAEEVKENALKWKKKAEETVAKGGYSERNLVGFIEEVARKTGTK
What is the function of this protein?
UDP-glucose-dependent glucosyltransferase involved in C-glycosylflavone biosynthesis.  Has a strict stereo selectivity and shows a preference for apigenin and luteolin as substrates, but could not recognize flavonols, anthocyanins and xanthones as glucosyl acceptors.  No activity with orientin (luteolin 8-C-glucoside) and luteolin 4'-glucoside.  Can use UDP-galactose instead of UDP-glucose as a sugar donor, but not UDP-glucuronic acid.
What are the official names of this protein?
UDP-glycosyltransferase UF6CGT1, GtUF6CGT1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: STRAP_DICDI
Sequence: MRQPLICSGHSRPVSDLSFSNENSDGSFIVSACLDGSPMLRNGENGDWIGTFEGHKGAVWSSRFNSTASQALTASADYTVKLWDTLNGSEILSIEHQSIVKTADFSNNNSRVVTGGSEKILRIFDLERPNDPLLQISGHTNTIKTATWSVHNDDIVLSGGLDEVIRIWDLRSGTQVSLCAKSSITSMEFSKDRRFLVTTAGNEVTFWDAQSFYPLKVYSLPFDVNCASLHPDNSKFIAGGSDFWVHVYDFSTGNEIEVNKGHHGPVNCCRFSPDGASFASGSLDGTIRLWKGM
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP.  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate.  Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP.  STRAP may play a role in the cellular distribution of the SMN complex (By similarity).
What are the official names of this protein?
Serine-threonine kinase receptor-associated protein, WD40 repeat-containing protein strap.
What is the protein family that this protein belongs to?
Belongs to the WD repeat STRAP family.
Protein: MTNA_THENN
Sequence: MKLKTKTMEWTGNSLRLLDQRKLPFIEEYVECKTHEEVAHAIKEMIVRGAPAIGVTAAFGYVLGFREYRSGDLKEWMKQVKEVLSRTRPTAVNLFWALNRMEKVFLENLKNENLGEILEEEAMKMAQEDIETNRAIGRNGAELIEDGSTILTHCNAGALATVDYGTALGVIRAAVEAGKRVRVFADETRPYLQGARLTAWELMKDGIEVYVITDNMAGWLMKRGMIDAVVVGADRIALNGDTANKIGTYSLAVLAKRNNVPFYVAAPISTIDPTIKSGDEIPIEERRAEEVTHCGGNRIAPEGVKVLNPAFDVTENSLITAIITEKGVIKPPFEENIKKILGV
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: DLTA_STAAT
Sequence: MTDIINKLQAFADANPQSIAVRHTTDELTYQQLMDESSKLAHRLQGSKKPMILFGHMSPYMIVGMIGAIKAGCGYVPVDTSIPEDRIKMIINKVQPEFVFNTTDESFESLEGEVFTIEDIKTSQDPVIFDSQIKDNDTVYTIFTSGSTGEPKGVQIEYASLVQFTEWMLELNKSGNEQQWLNQAPFSFDLSVMAIYPCLASGGTLNLVDKNMINKPKLLNEMLTATPINIWVSTPSFMEMCLLLPTLNEEQYGSLNEFFFCGEILPHRAAKALVNRFPSATIYNTYGPTEATVAVTSIQITQEILDQYPTLPVGVERPGARLSTTDEGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKFENGQWFIQGRIDFQIKLNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKNIKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKIDRKKIAEVING
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARND_SHIFL
Sequence: MTKVGLRIDVDAFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIEAKEAFHLRYNSDCRGAIPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVVRGNIAGREGWLGCQQIAGSR
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: ECPR_ECOHS
Sequence: MTWQSDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKDFVFINLNTDSLSEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAGLSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMQPKSIARIENCSVKTVYTHRRNAEAKLYSKIYKLVQ
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition.  Positively regulates the expression of the ecp operon (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator EcpR.
What is the protein family that this protein belongs to?
Belongs to the EcpR/MatA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOTB_DROYA
Sequence: MNFNMSMICFALLLIVTLCSAYSVQQRQADSLRVAEIIRTSQDENTKINRIQELLTIYNRMAPSLRPAERARLDKFISEHTQEVLIDGVPTQGGSRMKIIRKALTPAAKDVATGFFTELGASIASIFTNWFKSSTEPSH
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot B.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
What are the subcellular locations of this protein?
Secreted.
Protein: TF2B_XENLA
Sequence: MASTSRIDALPKVTCPNHPDALLVEDYRAGDMICSECGLVVGDRVIDVGSEWRTFSNDKAAADPSRVGDAQNPLLSGGDLTTMIGKGTGSASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITNMSDRINLPRNIIDRTNNLFKQVYEQKSLKGRSNDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETNVDLITTGDFMSRFCSNLGLTKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPADFKFDTPVDKLPQL
What is the function of this protein?
General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II).  Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA.  Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex.  Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle.  Associates with chromatin to core promoter-specific regions.  Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner; these IIB-recognition elements (BREs) are localized immediately upstream (BREu), 5'-[GC][GC][GA]CGCC-3', and downstream (BREd), 5'-[GA]T[TGA][TG][GT][TG][TG]-3', of the TATA box element.  Modulates transcription start site selection.  Exhibits also autoacetyltransferase activity that contributes to the activated transcription.
What are the official names of this protein?
Transcription initiation factor IIB, General transcription factor TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Non-acetylated form colocalizes with DNA in the G0/1, S and G2 phases of the cell cycle, but not during mitosis. Acetylated form colocalizes at transcriptionally silent mitotic chromatids during mitosis at metaphase, anaphase, and telophase phases of the cell cycle.
Protein: ZN697_MOUSE
Sequence: MEQEDNQGVCEYQTSEDRGMDSDLENSEDREGDPEERGMGSNPWDTEDRGHLEQEVDSNPQDDDLRGDSRERDRASTVCSEGRLSEEERAILREEEDDQPGVADMALFPGLSESDSISRSPRGEEDEEEEDEEEESAGENRLIEEEDPLPTPVLPWRRHLSLGGRHRGDKPAHRRFHRLHHPMAMDLGELDSLMASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAVASLEPFGLAGECGGVVGMMGMGMGVGMGVAGGFGAGPTLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSWRADLLKHRRLHTGEKPYPCPECGEAFSLSSHLLSHRRAHAAAGGGAGSAGSAAALRPFACGECGKGFVRRSHLANHQRIHTGEKPHGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSVSSHLFTHKRTHSGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFGCGQCEKRFSDFSTLTQHQRTHTGEKPYTCLECGKSFIQSSHLIRHRRIHTGNKPHKCAGCGKGFRYKTHLAQHQKLHLC
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 697.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCDX_ECO57
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIAEFADL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: M3K11_RAT
Sequence: MEPLKNLFLKSPLGSWNGSGSGGGGGSGGVRPEGSPKATAAYANPVWTALFDYEPNGQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGGQVGIFPSNYVSRGGGPPPCEVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAREWHKTTQMSAAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLPIPSTCPEPFAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMPRDSFHSMQEGWKREIQGLFDELRAKEKELLSREEELTRAAREQRSQAEQLRRREHLLAQWELEVFERELTLLLQQVDRERPHVRRRRGTFKRSKLRARDGGERISMPLDFKHRITVQASPGLDRRRNVFEVGAGDSPTFPRFRAIQLEPAESGQTWGRQSPRRLDDSSNGERRACWAWGPSSPKPGEAQNGRRRSRMDEATWYLDSDDSSPLGSPSTPPALNGNPPRPSPEPEEPRRSGPTERGNSSGTPKLIQRALLRGTALLASLGLGRDLQPPGGLSRERGESPTAPPPAQMASPCPPDLPSTPLIHLSQATPDARGPLTPAPLLLDLGVSSGQPSAKSPRREETRGRTVSPPPGISRSAPGTPGTPRSPPLGLISRPRPSPLRNRIDPWSFVSAGPRPSPLPSPQPAPRRAPWTLFPDSDPFWDSPPANPFRGGSQDCRTQTKDVGAQAPWAPEAGP
What is the function of this protein?
Activates the JUN N-terminal pathway.  Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7.  Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly.  Influences microtubule organization during the cell cycle (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Location is cell cycle dependent.
Protein: PANB1_ZYMMO
Sequence: MNQHGRSAEPGVASEGIAPYGDAHRGIAAKRKKTTTARISQMRVDGEKIAVLTAYDATFAAAADAAGVDCIMVGDSLGMVCQGRTTTVGVSLEDMLYHTRCVSQGIARADGSALIIADLPFGSYQQSNEQAIASAVQLMQAGAHMVKLEGGDWWTVDIVEFLVQRGIPVCAHLRLTPQTVSALGGYRVQGRSEEAAEKLRVDAGALDNAGASMMVLEMIPTELATSITSEMKSCATIGIGAGSGTAGQVLVMHDMLGINLGRMAKFVRNFMRDAEDVPTAFAAYVAAVKDGSFPDDKLHGFL
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 1, Ketopantoate hydroxymethyltransferase 1, KPHMT 1.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQC_XANAC
Sequence: MTALLGPDQLEADLRAIGARLYHDQHPFHALLHHGKLDRGQVQAWALNRFEYQRCIPLKDAAILARMEDPALRRIWRQRILDHDGNSASDGGIARWLHLTDALGLDRTLVESGRALLPGTRFAVQAYLHFVREKSLLEAIASSLTELFAPNIIGQRVAGMLKHYDFVSSEALAYFEHRLTEAPRDSDFALDYVKQHADTVEKQALVKAALHFKCSVLWAQLDALHVAYVAPGIVWPDAFVPDRDASRVAA
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: TPPC1_DICDI
Sequence: MIYNIYIFNKDGTCIYYEDWNKKKQSQNQSEDQKLLFGMLYSLKAFITSSSPKKIDDKTGFHCYKTSTYKLHYYETLSCIKFIIMSDPNVPDLRDDLKKIYSQIFVEYVIKNPIYKHGTTVKCDTFINQLNLYLKQMPSFSS
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET5 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.