PharMolix/UniProtQA huggingface dataset:
Protein: HP4_ELSFA
Sequence: MDRSQALYYPWDSFCLLSRCSIFILSTTLEDSRTLLSHLGLQNPHEVQGTFVPEARVPGVRLEATAGHQSLSEPSGWVYYRHKHSDLVDPADLHLQGASYRRSTIRSYLMVKKVLYLVSSAP
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of elsinochromes, pigments consisting of at least four interconvertible tautomers (A, B, C and D) that have a core phenolic quinone to which various side chains are attached and which play an important role in fungal pathogenesis (PubMed:18957608).  The non-reducing polyketide synthase PKS1 was proposed to iteratively catalyze decarboxylation between acetyl-CoA and malonyl-CoA subunits for polyketide chain elongation.  The released polyketide undergoes cyclization to form an aromatic ring, and proceeds via serial modification steps to produce the heptaketide back- bone of elsinochrome.  As elsinochrome has a symmetrical structure, two identical heptaketides are fused to form a core 1,2-dihydrobenzo-perylene ring structure, which can then be successively modified to produce the various derivatives of elsinochrome.  Some of these reactions may be cooperatively carried out, at least in part, by the products of RDT1, OXR1 and PKS1.  PRF1, embedded within the elsinochrome cluster possibly functions to stabilize some of the biosynthetic enzymes required for elsinochrome production.  As prefoldin is a hexamer containing 2 a and 4 b subunits, additional prefoldin subunits, whose coding genes may not immediately link to the elsinochrome biosynthetic gene cluster, are required to fulfill the chaperone function.  In addition, no methyltransferase-coding gene exists within the biosynthetic gene cluster, even though elsinochrome has four methyl groups at positions C3, C7, C8 and C12.  Apparently, the identified gene cluster does not contain the entire entourage of genes responsible for elsinochrome biosynthesis.  Once elsinochrome is synthesized, it must be exported outside the fungal cells, which is probably accomplished by the ECT1 transporter, to avoid toxicity (PubMed:21199563).
What are the official names of this protein?
Elsinochromes biosynthesis cluster protein HP4.
Protein: GUAA_FRASN
Sequence: MNESPRASYGSTGAHPGYDPVLVIDFGAQYAQLIARRVRECHVYSEIVPWDMPVAEILARRPAALILSGGPKSVYSPGAPRVDPALFAAGVPVLGICYGHQVMAQALDGTVARTGTAEYGATRLRVDDPGVLFDGLPTSQQVWMSHGDSVTAAPPGFRVTASTPSTPVAAFEDPTRRLYGVQFHPEVVHSERGMDVLRHFLLVGAGCRPSWTMINIVEEAVTAVRAQVGNGRLICGLSGGVDSAVAAALVQRAVGDTLTCVFVDHGLLRAGEAEQVERDFVASTGVDLVHVKAADRFASALAGVTDPEQKRKIIGREFIRVFEESARELDARAEAEGTHIGFLVQGTLYPDVIESGSPTAAKIKSHHNVGGLPDDLQFDLVEPLRTLFKDEVRRLGEELGLPEDIVWRQPFPGPGLAVRIIGEVTPERLEIVRAADAVVRDEIRRAGLDREIWQVFAVLLADVRSVGVQGDERTYGFPVVLRAVTSEDAMTADWARLPYDLLERISNRVVNEVGQVNRVVYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: CH10_ECO55
Sequence: MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: Y1816_PARMW
Sequence: MASTSSFDVVSDFDRQELVNTLDQVRRDVGNRYDLKDSNTEIQLEETELVITTASDMTLQAVEDVLRAKATKRNLSLKIFDFQTPESVGGNRVKQVVKLRKGLSQEIAKKLSKIVRDELKKVTVAIQGESVRITGKSKDDLQAAIQLVKSKEDELDVPLQFENYR
What are the official names of this protein?
UPF0234 protein SYNW1816.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: TELL_STAA8
Sequence: MTENKSFKESHPLDDFISDKELSNTTIQKEKLTIEQQKQVDTISKQINPLDNEGLLAFGSDLQKQMSQFSHQMLDEVQSKDVGPIGDTLSDLMSKLKSVNPNELNTDKPSMLKRIFSRAKSSINEIFSRMQSVSAQVDRITIQLQKHQTHLTRDIELLDTLYDKNKQYFDDLSLHIIAAQQKKLQLENEKLPQLQQQAQQSTNQMDIQQVADMQQFIDRLDKRIYDLQLSRQIALQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTLMRQRNAVAAQRAVTDTTNDLLTANAEMLKQNAIETATENERGIVDLDTLKRTQRNIIETIEETLIIQQHGREERQLAEKELQQLEQDLKSHLVNIKGPNKQS
What are the official names of this protein?
TelA-like protein SAOUHSC_01408.
What is the protein family that this protein belongs to?
Belongs to the TelA family.
Protein: RNH2_SACS2
Sequence: MRVGIDEAGRGALIGPMIVAGVVISDTKLKFLKGIGVKDSKQLTRERREKLFDIVANTVEAFTVVKVFPYEIDNYNLNDLTYDAVSKIILSLSSFNPEIVTVDKVGDEKPVIELINKLGYKSNVVHKADVLFVEASAASIIAKVIRDNYIDELKQVYGDFGSGYPADPRTIKWLKSFYEKNPNPPPIIRRSWKILRSTAPLYYISKEGRRLW
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGLR_RALSL
Sequence: MNHRYTLLALAAAALSAGAHATGTSVTAPWGEVAEPSLPADSAVCKTLSASITPIKGSVDSVDGNPANSQPDASRIQSAIDNCPAGQAVKLVKGSAGESGFLSGSLKLKSGVTLWIDTGVTLFASRNPADYDNGLGTCGTATTSNDKSCNALIVARDTAGSGIVGAGAIDGRGGSLVTSGPNANRLTWWDIAYLNKTKGLNQQNPRLIQTYNGSAFTLYGVTVQNSPNFHIVTTGTSGVTAWGIKIVTPSLAYAVAGYKCPSGSTPDKVTPATCFTPETVKNTDGFDPGQSTNVVLAYSYINTGDDHVAVKASSGPTRNLLFAHNHFYYGHGLSIGSETNTGVSNMLVTDLTMDGNDSSAGNGLRIKSDASRGGKVTNIVYDGICMRNVKEPLVFDPFYSSVKGSLYPNFTNIVVKNFHDLGSAKSIKRTMTFLGYKANKQKNPLTITLDNVVFDGTLPAFEGSHYGGPASPNGVHFTFGGTGPVSFADAIVTSSTTDVTVTGTPGTAAAVDCSKAFVPLKSVAPTSPI
What is the function of this protein?
Contributes to the wilt disease production on tomato.
What are the official names of this protein?
Polygalacturonase, PGA, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YBAK_HAEIN
Sequence: MTPAIDLLKKQKIPFILHTYDHDPNNQHFGDEAAEKLGIDPNRSFKTLLVAENGDQKKLACFVLATANMLNLKKAAKSIGVKKVEMADKDAAQKSTGYLVGGISPLGQKKRVKTVINSTALEFETIYVSGGKRGLSVEIAPQDLAKVLGAEFTDIVDE
What is the function of this protein?
Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity.  Probably compensates for the lack of Cys-tRNA(Pro) editing by ProRS.  Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs.  Does not cleave Pro-tRNA(Pro).
What are the official names of this protein?
Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK.
What is the protein family that this protein belongs to?
Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2539_KLEP7
Sequence: MSKSLTIIWQYLRAFVLIYACLYAGIFIAGLLPITIPGSIIGMLILFVLLALQIMPPQWVNPGCNILIRYMALLFVPIGVGVMQYWDLLRAQLGPVVISCAISTLVVFVVVSWSSHLVHGERKVIGQKGKEE
What are the official names of this protein?
UPF0299 membrane protein KPN78578_25390.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y477_MYCTU
Sequence: MKALVAVSAVAVVALLGVSSAQADPEADPGAGEANYGGPPSSPRLVDHTEWAQWGSLPSLRVYPSQVGRTASRRLGMAAADAAWAEVLALSPEADTAGMRAQFICHWQYAEIRQPGKPSWNLEPWRPVVDDSEMLASGCNPGSPEESF
What are the official names of this protein?
Uncharacterized protein Rv0477.
What is the protein family that this protein belongs to?
To M.leprae ML2452.
Protein: GCY23_CAEEL
Sequence: MRRELFIFLLLLGECANVKVKVGHIGAVGSMRNAEKILQLSKEQLTQEGVLGNDFDIEILNQMGCGESYEGVAVGADMYHVQGVRAFIGPYCNAELDAVAKMATFWNIPVVGYMASSNSFADKTIFKTLARVSLRTTNSLAEAAAALIKHYGWNKVAIATNTGAVAFERVQSFEEVFHQRGINVVRKIMLEEYTNAKAIMNSGLLQELENSARVVVCAFSSTRDMNKEFMQAVTLSGMNNANYAWILPWLQLETKDMAPWLGENGEYQQNVKDHFANSFIIDDVNGFDNTLVTPFKERLEASGYSTDDLEMKNIYGYIHLYDALRLYALAVRATMNETGNENSYLNGKEVWNHMRRITFPGLVSNAGVTSGTVMMDDIAERAPVYAAFYVPPNSDTVRKVCELEPVMLTNCDGTKTGNGCYELQVTDLSTGFWPSIDGSLPADEPACGFRNEKCDYTTLIIGGCIVLLIILLIICFFILSRVCENRALANTPWRIYRDDFRTIQENEMKSMLSIGSSKTKMSNMSMFVKHHAVVGTNTHASFHLYPQRRPIVFNRQDLQLLNQMKQAVHDNLNPFLGMSFNEKEEMVVLWKFCSRGTIQDMIYNQEVSLDSKFHGAFIRDITLGLEYLHSSIIGYHGSLTPWSCLIDRNWMIKLTDYGIANPLERWEKLGLISTETLKEGDDKSGSAQKTSLLYQPPEMLKNKESNRTRRMDQSWVKQSQARRQMGDIYAFGMVMHEILFRALPFPNGTNVSEVMDYIRDGTKTFRPTVHDRTQIHPDLVALLLDCWNENPEVRPSIRRVRLNTENYLKVKGSLVDQMMRMMEQYANNLEKLVAERTGMLEEANVRADKLLGQLLPKYVANELKMGRSVPAKTFDMATVMFSDIVGFTTICSSSTPLEVVSMLNSIYSKFDDAINKHGSYKVETIGDAYMIVSGIPEENGNEHIRNICNTALELMLLLKTYEIPHRRNVKLRIRLGIHTGTVAAGVVGLTAPRYCLFGDTVNVASRMESTSEPEKIQMSQEARDFCVRYYSEFQITLRGTVEAKGKGPVTSYWLLGKQSESQMQQQNFSQLGI
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).  Regulates thermotaxis responses in AFD sensory neurons.  May regulate AFD neuronal activity such as calcium responses to temperature gradients (PubMed:16415369).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-23.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, cilium. Note=Localizes exclusively to the sensory ending, known as cilium, in AFD neurons.
Protein: HEM1_XANOR
Sequence: MTLWVLGLNHQTAPVDLRERAAFAGDALPRALESLRALPQVSEAALLSTCNRTELYAMADEARSLVNWLETHAPGLSGYLYQHQEAEAVRHLFRVATGLDSMVLGEPQILGQVKDAWAVARAHGALGSGLDRLFQQTFSVAKRARTDTRVGANPVSVASTAVRLAQESFARLNESTVLLIGAGETIELAAKHLSEGRVRRLLIANRTLAHAQTLASQHGGYALPLTDLERHLAEADVVFSATAAREPLVTRVQVEQALRARKRKPMLLFDLAVPRDIEASVDELSDAYLYTVDDLERAVEDNRRGRREAADQAEAIIDLQVARYVETLQATTRQAPLKRLRAFGDSTRDELLAKARQQLHNGKPTDEVLEQLAHALTNRLLHPPTAALRDAALNNDLELTTAADRLFPEKPGYQHPPIATPIVRTDDADPAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: THRC_METAC
Sequence: MYHLKCIECGAEYSRDEVIYTCSKCDGLLDVIYDYSSIKIDMEKLKTECPSVWKYAKLLPVEREPVTIQEGGTPLYKCDRLAEKIGIKKLYVKHEGMNPTGSFKDRGMTVGVTKALELGMNTVACASTGNTSAALAIYGAKAGIPVVVLLPAGKVALGKVAQALMHGAKVLSIRGNFDDALALVRTLCSQEKIYLLNSINPYRLEGQKTIGFEIADQLDFKVPDRIVLPVGNAGNITAIYKGFREFKILGITDSLPKMTGIQAEGSCPIVKAIKSGAPAITPEENPETVATAIRIGNPVNATKALSAIRESGGTAESVTDEEILAAQKDLARLEGIGVEPASAASVAGLRKLVDMGVIGRDETVVCITTGHLLKDPQTVIDVCEEPTVVDANIDAIREAIFGKAK
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.  Does not catalyze the conversion of O-acetyl-L-homoserine into threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: Y4189_MYCPA
Sequence: MTRTHDDEWDLASSVGATATMVAAGRAMATKDPRGLIDDPFAEPLVRAVGVDFFTKMMDGELDLDAIENATPVRIQSMVDGMAVRTKYFDDYFVDATDAGVRRVVILASGLDSRAYRLPWPAGTVVYEIDQPRVIEFKSNTLAEVGAEPTATRRTIPIDLRGDWPAALSAAGFDPAAPTAWLAEGLLIYLPPEAQDRLFDNITALSAPGSTIATEFVPGIVDFDAERVREMSGSFRQHGVDIDMASLVYAGERNHVIDYLNGLGWRAEGVTRTELFHRHGIEVPAPENDDPLGEIIFISATRTR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_4189c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: CION_CIOIN
Sequence: MGSNIVIYFSIIVIVTLNVNGVPASDLFKSVSQYHIPRSKVINKETVTKPLQFQRAICRLLQKLGEETFARLSQSELEAKQLDLIKTCYQANSFGDNENQGHMQRMDRNYYGWMDFGKRAIEDVDYEY
What are the official names of this protein?
Cionin.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CSPL6_PTEAA
Sequence: MEVSHPAVHPVAVPPVLTEPPARVRMKDYQGMPGTLGGLALRLGQLGFAVLSFSIMVSTPDFSQVTAFCYLVAATVLQTLWSSITAVVDIYALSVRRSLHHSLLVGLFAVGDGVTSTLTFAAACATAGITVLIDNDLDECGQNHCGRFEAAAAMAFLSWIMAAPSFLLAFWSFGNKIVCF
What are the official names of this protein?
CASP-like protein 5A1, PaCASPL5A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURL_RHORT
Sequence: MSQSASTPATPITAKIVAEHGLTEAEYAKVLAIMGREPNLVELGIFSVMWSEHCSYKSSKKWLKTLPTTAPWVIQGPGENAGVIDIGDGLTAIFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVANLNALRFGDPSDPRTRHLISGVVAGIGGYGNCVGVPTVGGEVNFHASFNGNNLVNAMTVGVARADRIFYSAAAGIGNSVVYVGSKTGRDGIHGATMASAEFSEDSEEKRPTVQVGDPFTEKLLIEACLELMNTDAIVAIQDMGAAGLTSSCFEMASKGGMGVDLALDRVPMREEGMTPYELMLSESQERMLMVLKPGKEDMARALFEKWELDFAIIGTLTDSGRMVLTWHGEVVGDLPIDPLAAASPEYDRPWEPTPMAAAADLSGAEDTPWSEALLRLIGCPDVASRRWIWEQYDHLVMGNTLQRPGGDAAVIRLDEAPGKGLAMTTDCTPRYVHADPVEGGKQAVAEAWRNLTAVGARPLAITDNMNFGNPEKPRIMGQFVGACQGISEACLALDFPVVSGNVSLYNETNGQAILPTPTIGGVGVLDNVEASVSIALKAAGEAILVAGGFHGSTGAWLGQSLFLREILGREEGAPPPVDLAAERKVGDFVRGLILGASVTACHDLSDGGLLVALAEMAMAGDLGAELTLEGHPDNGRLFGEDQGRYLLTVAEGDRDAVVAAAEAAGVPLRVVGTTGGDALVVNGFVGPSVAALRKVHEEWLPTYMAG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLMA_SHIF8
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLASQILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: OSTCN_BOVIN
Sequence: MRTPMLLALLALATLCLAGRADAKPGDAESGKGAAFVSKQEGSEVVKRLRRYLDHWLGAPAPYPDPLEPKREVCELNPDCDELADHIGFQEAYRRFYGPV
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL_HYOLA
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIETVVGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPSYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVCARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREMTLGFVDLLRDDFIEKDRSRGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFDPVDKLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UCDH_STRP1
Sequence: MARPLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLNMDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSFLDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTPESREAALKAADKLVQRYQDKGGFIQAWGELGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASAYHTFYFDPETGDPVKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGMTHYFLNRLPKDQVSYWDLIFGDGSEQSRDSSATAIAVCGIHEMLKTLPDHDPDKKTYEAAMHSMLRALIKDYANKDLKPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFYKDWNPYW
What is the function of this protein?
Catalyzes the hydrolysis of unsaturated hyaluronate and chondroitin disaccharides.  Also degrades unsaturated heparin disaccharides.  Releases 4-deoxy-4,5-didehydro D-glucuronic acid or 4-deoxy-4,5-didehydro L-iduronic acid from chondroitin disaccharides, hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1->3) and (1->4) bonds.  Prefers sulfated glycosaminoglycans compared to unsulfated glycosaminoglycans.  Probably required for mammalian cells invasion through the degradation of extracellular sulfated glycosaminoglycans such as chondroitin and hyaluronan.
What are the official names of this protein?
Unsaturated chondroitin disaccharide hydrolase, Unsaturated glucuronyl hydrolase, SpyUGL.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 88 family.
Protein: SYGA_BORPE
Sequence: MLTFQQIILTLQDYWDKQGCALLQPYDMEVGAGTSHTATFLRAIGPEPWRAAYVQPSRRPKDGRYGENPNRLQHYYQYQVVLKPAPPEILDLYIGSLKALGIDPTQHDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLDCTPTTGEITYGLERLAMYLQDVESVYDLVWTEGANGNRVYYRDVFHQNEVEQSTYNFEHASADMLFAHFNDYEAEAKRLMDVPLALPAYEAALKAAHTFNMLDARGAISVTERAAYIGRIRNLSRAVAQAYYDSRERLGFPMLAGRKAAGEAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_BURO0
Sequence: MSNSRQHQGHFARKRFGQNFLVDHGVIDSIVATIGPARGQRMVEIGPGLGALTGPLIERLATPESPLHAVELDRDLIGRLQQRFGALLELHAGDALAFDFRSLAAPGDKPSLRIVGNLPYNISSPLLFHLMTFADAVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVMEKMLDVPPESFQPPPKVDSAIVRMIPYEPHELPDVDPVLLGEIVTAAFSQRRKMLRNTLGDYRETIDFDALGFDLARRAEDVSVAEYVGVAQALAALRKAG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
Protein: SOX9_XENTR
Sequence: MNLLDPFMKMTEEQDKCMSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGDPELKKETEDEKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRIQHKKDHPDYKYQPRRRKSVKNGQSEQEDGAEQTHISPNAIFKALQADSPHSASSMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGKPDLKREGRPLQESGRQPPHIDFRDVDIGELSSEVISTIETFDVNEFDQYLPPNGHPGVGSTQAPYTGSYGINSTPSATPGAGPAWMSKQQQQQQQQPQPPQHSLSTINSEQSQSQQRTHIKTEQLSPSHYSDQQQQHSPQQLNYSSFNLQHYSSSYPTITRAQYDYTEHQGSNSYYSHASGQNSGLYSNFSYMNPSQRPMYTPIADTTGVPSIPQTHSPQHWEQPVYTQLTRP
What is the function of this protein?
Transcription factor that plays a key role in chondrocytes differentiation and skeletal development.  Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including COL2A1.  Plays a central role in successive steps of chondrocyte differentiation.  Absolutely required for precartilaginous condensation, the first step in chondrogenesis during which skeletal progenitors differentiate into prechondrocytes.  Together with SOX5 and SOX6, required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes, the second step in chondrogenesis.  Later, required to direct hypertrophic maturation and block osteoblast differentiation of growth plate chondrocytes: maintains chondrocyte columnar proliferation, delays prehypertrophy and then prevents osteoblastic differentiation of chondrocytes.  Also required for chondrocyte hypertrophy, both indirectly, by keeping the lineage fate of chondrocytes, and directly, by remaining present in upper hypertrophic cells.  Low lipid levels are the main nutritional determinant for chondrogenic commitment of skeletal progenitor cells: when lipids levels are low, FOXO transcription factors promote expression of SOX9, which induces chondrogenic commitment and suppresses fatty acid oxidation.  In addition to cartilage development, also acts as a regulator of proliferation and differentiation in epithelial stem/progenitor cells (By similarity).  Unlikely to play a role in sex determination but may function during testicular and ovarian differentiation (PubMed:18692165, PubMed:18816826).
What are the official names of this protein?
Transcription factor Sox-9, Xt-sox9.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Restricted to the nucleus of Sertoli-like cells in the testis, but localizes to the cytoplasm of previtellogenic oocytes in the ovary before being translocated into the nucleus of vitellogenic oocytes.
Protein: BET_FFV
Sequence: MASKYPEEGPITEGVEEDFNSHSTSGLDLTSVGKNPEHPRRILLVLQHLIAYAEATIKKQDVPGPLLPILSPYVMAWDNPQNVVTRLVNLGESWKKYLLSPGWKDCGERDLTMLTRELLVPGIGLVQIAATLTKTYVLMCNGRCITGSRTDPDCDPLFCKLLCWKQNIQDPRECNLEEWCLYSLDPEHDPLWDPKMIVRRHRNLLPYCMRPFLIWMNYISHNPLTQQCIMMKTLNMLWRAQADDPSDVASLYPRVKVFKASHFDIFGSASGNSEERVSWAKENSHRGEYSLLPSSDDEEEEMSEREELLCHINQCQQKLFYPGGTTDVLGMESNVWLTKFVNIKFPKGTKVILPDGRKFIACDPELKPLLQELKFLDRATSESSDSE
What is the function of this protein?
May be implicated in the establishment and/or maintenance of viral persistance.  Bet is required for viral replication.
What are the official names of this protein?
Protein Bet.
Protein: VATF_HALLT
Sequence: MSQEIAVVGSPEFTTGFRLAGVRKFENIPDDEKDERLDDAVERTLDDEGTGIIVMHTDDLDHLSRGTREAVEGSIEPVLVTLGGSGAGSGGLRDQIKRAIGIDLMEEDD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.