PharMolix/UniProtQA huggingface dataset:
Protein: UVRC_BURP0
Sequence: MTSPDAPESRFEPKPILAQLPHLPGVYRYYDAQDAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMITRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHRFPRMAYYRGAVDKKNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCSAPCVGAIGEEDYARDVDNASRFLLGRQGEVMGELERKMHAFAAELKFEQAAAVRNQMSSLAKVLHQQAIDVGGDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPAHVETALALAGDIEALAGEGAGDGVQAAAQPAQAPLATDADATDAAATEAKTVTAAAAARAGARTAQAAGARAAASAEGDVERRAEGETHARADAREAAALPDGAAAAQEADADVDAAPLETEVLEAFIAQHYLGNRVPPVLVVSHAPANRELIDLLVEQAGHKVAVVRQPQGQKRAWLTMAEQNARLALARLLSEQGSQQARTRSLADVLGYESDDLAQLRIECFDISHTMGEATQASCVVYHHHRMQSSEYRRYNIAGITPGDDYAAMRQVLTRRYEKMVEEAAAEASADEAAGIDGNAVHAAASAGRLPNVVLIDGGRGQVEIARQVFSELGLDISMLVGVAKGEGRKVGLETLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASVDELASVEGISRALAEQIYRQLH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_METMJ
Sequence: MARMYARRRGTSSSVRPYRKEAPEWSNTDATEIEKIVVDLRKDGMSTSQIGLVLRDRYAVPDVKLATGKRIGEILREKGLESEIPEDLRNLMEKALGIRKHLAENNKDVHNKRQLQIAESKVRRLVKYYVRSGRMPKGWTYKPETAEILLTR
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CJ067_HUMAN
Sequence: MMALVRDRRAHYVMSIVIRWVHCFSSSLRGTFGTRWEAMKAKATELRVCCARRKREAREFKPPQMRGSTRLNISDDLKIGFFSTDHATQTDSSEILSVKELSSSTQKLAQMMKSLQVDFGFLKQLLQLKFEDRLKEESLSLFTILHDRILEIEKHYQQNEDKMRKSFNQQLADAIAVIKGMYQQFFEVEEENVSLQDASTVKTNILLRKLKEKEEVIKELKEELDQYKDFGFHKMESFAKETSSPKSNLEKENLEYKVENERLLQIISELEEEIQINLKENSGLEDELISMKEMAEKDHKTIQKLMDSRDRLREELHYEKSLVQDVINKQKEDKEMRKKYGSLSVKVARSAKGREASLSPWPKSPPSTTALRPHSATMSVSSAGAQKAKMPKKALKEDQAVVEDKHGLESQIEALKANLENEKKKVERFRKEADRLNKSWEKRFFILRNSFHVLKNEMFTRHTLFRQFAVLADTSFNYIKVKPLLVQSRTTMTAISSSSHCTSSIDGKHVDVVSDQAALQLSPKGKLSESPKEESLEEPSMRQSSPAETVD
What are the official names of this protein?
Uncharacterized protein C10orf67, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NADK_HAHCH
Sequence: MEQFRNIGLLGRMGSVQVVETLKRLKNYLVGEGYAVILEEATAAVLPGHNVQVSSKKMLGEICDLVIVVGGDGSLLGAARALAGCNVPVLGVNRGRLGFLTDITPTEMEPQLAEVLSGKYVEESRFLLDAYVKRNGEPVGYGCGLNDIVLHPGKSTRMIGFDLYIEGQFVNSQRSDGLIVSTPTGSTAYALSAGGPIMHPRLDAIVLVPMFPHTLSSRPIVVDGNSEIKIIIGDYNQTYPHVSCDGQTHVTCAPGDTVTICKKPQKLRLIHPMNHNFYQICRDKLGWSSSRDQGGQ
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_BRUSU
Sequence: MNSRLIVTGTDTGIGKTVFSAALCHALGAAYWKPVQSGLEEETDSEIVARLAQASPQRILPEAWRLNTPASPHLSARLDGVEIRPEEMHIPATSLPLVIEGAGGLLVPLNDKTLFADLFAIWRIPAILCARAALGTINHTLLSLEAMRSRDIPVLGVAFIGEANEDTETTIAHLGRVKRLGRLPLLDDLSPEKLHHSFARNFHIDDFAGVAR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3235_METAC
Sequence: MTSSRFIITVIGSDRVGIVARITTVMASYNVNIVDISQTIMQGIFTMIMLAEAPKENFDLAAFQHAMDAEGKSLGVEVKVQHEDVFRFMHRI
What are the official names of this protein?
UPF0237 protein MA_3235.
What is the protein family that this protein belongs to?
Belongs to the UPF0237 family.
Protein: DSVA_MEGG1
Sequence: WKDDIKIDQEAVKAYVGGEFKPNAGAHAGRDWGKFDIEAEVVGLCPTGCMTYESGTLSIDNKNCTRCMHCINTMPRALKIGDERGASILVGAKAPVLDGAQMGSLLIPFIAAEEPFDEVKEVIENIWEWWMEEGKNRERLGETMKRVGFQKLLEVTGTKAVPQHVSEPRHNPYIFFKEEEVPGGWSRDISDYRKRHMR
What is the function of this protein?
Part of the complex that catalyzes the reduction of sulfite to sulfide.  The alpha and beta subunits may have arisen by gene duplication.  They both bind 2 iron-sulfur clusters, but the alpha subunit seems to be catalytically inactive, due to substitutions along the putative substrate access channel, and because it binds sirohydrochlorin (the dematallated form of siroheme) instead of siroheme.
What are the official names of this protein?
Sulfite reductase, dissimilatory-type subunit alpha, Desulfoviridin subunit alpha, Dissimilatory sulfite reductase subunit alpha, dSiR alpha, Hydrogensulfite reductase subunit alpha.
Protein: OBP69_ANOGA
Sequence: MDRLLLVLLSSASLLLTVYGIKHHIVTKSWSEAQSDCLQYLRVESPGRYLSHRYRDNQTSKQLIFCIILNLRIYDPTQNVLRLKAMGQFFNPDKTDTLYVNRTNACLLRVKVPPLVDSSEDSQLYSGVMGTLYEVFRCFYHCYGNINAIAPKLPPTVLELEKIQQECARMVGVSERLLDGGLQLSSHPRYSKLPRCIMLRSGGSVDYLTHRNNSSRRFKLKKNVENDTL
What is the function of this protein?
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
What are the official names of this protein?
General odorant-binding protein 69.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: NCAP_IBVK
Sequence: MASGKATGKTDAPAPVIKLGGPKPPKVGSSGNASWFQAIKAKKLNSPPLKFEGSGVPDNENLKTSQQHGYWRRQARFKPSKGGRKPVPDAWYFYYTGTGPAADLNWGDSQDGIVWVAAKGADTKSRSNQGTRDPDKFDQYPLRFSDGGPDGNFRWDFIPLNRGRSGKSTAASSAASSRAPSREGSRGRRSGAEDDLIARAAKIIQDQQKKGARITKAKADEMAHRRYCKRTIPPGYKVDQVFGPRTKGKEGNFGDDKMNEEGIKDGRVTAMLNLVPSSHACLFGSRVTPKLQPDGLHLKFEFTTVVSRNDPQFDNYVKICDQCVDGVGTRPKDDEPKPKSRSSSRPATRTSSPAPRQPRPKKEKKTKKQDDEVDKALTSDEERNNAQLEFDDEPKVINWGDSALGENEL
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the gammacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: CH10_WOLPP
Sequence: MSSVNLNVLDDNVLIKPITEEKQGGIVLPSSAEKKPTKGEVIAIGSGSRNSSGERIALTVKTGDKVFYRQWAGTEVEHDNEKYVVMKESDLLAVIK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP7_GIBZE
Sequence: MADDGMLLNFDLGSGPVKPQVKFKGGRWRDRKQAEKSARIASGKQSQPKSSTDGPDDGRSSKRQRTDDGDFDNGFDYKSANRFGSRPKHFDNDGHGGASGQSRSHQSDGKSKQVISRLFSFNPAQKTEADEKQGEWTAPEATNAPLSDVANFGTLTISARLVDELGKMGLERPTGIQNKVIPHMLTSSSDAFVQAETGSGKTLAYLLPILHRVLLLSVKGGAQIHRDSGAFAIIVAPTRELAKQVHTVLEKLIRPFPWLVSTAITGGESKKAEKARIRKGVNFLVATPGRLADHIDNTKALNLSIVRWLILDEGDRLMDLGFEDDLKKVITALKAVDVSDTLPDGTPLKALPERRVTVLCSATMKMNVQKLGEMSLADATFLAAKKEDMELDVQKSEMKAPAQLHQYYSVVPAKLRLVTLISYLKSTFSRRGKTMKAIIFISCADSVDFHYELLRDPNTTEAPVAASKEAESISKTVSKAAYITSPASPEVVLHRMHGSLSQPIRTATLKSFSACKSPSLLITTDVSSRGLDIPSVDLVIEYDPAFSFADHIHRVGRTARAGKPGDALLFLLPGTEEGYIELMKGSTTPTSQSYDSILQKGMMTKLEFPVETTAKPEDGHSFHDKAESLQLHIEQRLLEDTKRLELARNGFKSHIRAYATHTKEERKHFDISELHLGHTAKSYGLREAPGGIGQGVERKTKKRTNKGVEKDPEQAAGDERQNQNIIRKKSMMLMNSAADEFNIG
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP7.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ZNUC_SHIFL
Sequence: MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDILPALKRVQAGHLINAPMQKLSGGETQRVLLARALLNCPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFGPRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: THIG_GLUDA
Sequence: MLFYGTELKSRLMLGTAQYPSPEILSDAVRAAEAGVVTVSLRRESAGQRAGQAFWSMIRDLGVPVLPNTAGCHTVKEAVTTAHMAREVFDTDWIKLEVIGESDTLQPDMFGLVEAARILSRDGFKVFPYMTEDLVGAERLLQAGCEVLMPWGAPIGSGKGLNNVFGLRALRAHFPDVPLVVDAGIGLPSHAAQAMELGYDAVLINTAVAKAGDPVRMARAFRLAVEAGLIAREADPIEERDMAAPSTPVLGRAMLA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_BORPE
Sequence: MPYSYTEKKRIRKSFAKREDVQNVPFLLATQLQSYLTFLQADTATSDRVNEGLQAAFSSIFPIVSHNGMARLEFVSYALGEPVFDVKECQQRGLTYASPLRAKVRLVLLDREVSKPTIKEVKEQEVYMGEIPLMTGTGSFVINGTERVIVSQLHRSPGVFFEHDRGKTHSSGKLLFSARVIPYRGSWLDFEFDPKDVLFFRVDRRRKMPVTILLKAIGMTPESILAHFFDFDNFELKSEGGMMEFVAERWKGEMARFDIADRDGKVIVEKDKRINAKHLRDLAAGGIQRVSVPEDFLYGRVLAKNIVDPDTGEVVAHANDEITESVLNAMRAANVRDIQTLYTNDLDRGPYISQTLRADETADQMAARVAIYRMMRPGEPPTEEAVEALFQRLFYSEETYDLSRVGRMKVNSRLGRGDDSTGPMTLTNEDILETIKVLVELRNGRGQIDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAETENLMPHDLINSKPISAAIKEFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSMALYARLNEYGFLETPYRKIIDGKVSDQIDYLSAIEESHYVIAQANAALDDEGRFVDDLVACREAGETMLTAPGNVHYMDVAPSQIVSVAASLIPFLEHDDANRALMGANMQRQAVPCLRPEKPLVGTGVERTVAVDSGTTVQALRGGVVDHVDADRVVIRVNDEENVAGEVGVDIYNLIKYTRSNQNTNINQRPIVARGDKVAKGDVLADGASTDLGELALGQNMLIAFMPWNGYNFEDSILISERVVADDRYTSIHIEELTVVARDTKLGPEEITRDISNLAETQLNRLDDSGIVYIGAEVSADDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMTGTVIDVQVFTREGIVRDKRAQSIIDDELRRYRQDLNDQLRIVENDQFDRIEKMLVGKTVNGGPRKLAKGATLTKAYLADLDRWQWFDIRLADEQHAVVLEQAKESLEQKRHQFDLAFEEKRKKLTQGDELPPGVLKMIKVYLAVKRRLQPGDKMAGRHGNKGVVSRITPVEDMPHMADGTPADIVLNPLGVPSRMNVGQVLEVHLGWAAKGVGYRIADMLRDERTAQAKSVRGYLEKVYNTTGSSAHIDSLTDEEVLELANNLKKGVPFATPVFDGATEEEIGKMLELAYPDDVAARMRLTASRSQAWLYDGRTGEQFERPVTIGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLTVKSDDITGRTKVYENIVKGDHVIDAGMPESFNVLVKEIRSLALDMDLERN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: COAE_LATSS
Sequence: MTYFLGLTGGIATGKTTVSQMLAQQGIPIIDGDQVAHQVLANNQSVQAQIQATFGKQLVQDGQVDRAALGKLVFGNQAALAQLNAITAPVIRETIMTEMVQAKAHQVPLVVLDLPLLYEQHYETVCDGVLVVYLPVEKQLARLMARNQLSREDALKRINSQASLAEKRDRADFVIDNQGSLDQLKAQLKTVLEGVCHKSGMS
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDKB_MERHU
Sequence: MEQTFVAIKPDGVQRGLCGEVMKFIQPMKHYLDLKDMPFYAGLCKYMSSGPVFAMVWEGEGIVKMMLGETNPADSKPGSIRGDFCINIGRNIIHGSDTVENAKMEVGLWFKPEEFVAYAEKAKAWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.
What are the official names of this protein?
Nucleoside diphosphate kinase B, NDK B, NDP kinase B.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, lamellipodium. Cell projection, ruffle.
Protein: GBRA2_BOVIN
Sequence: MKTKLNSSNMQLLLFVFLAWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLPGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREPVLGVSP
What is the function of this protein?
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:2842688).  Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity).  The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity).  The alpha2/beta2/gamma2 receptor exhibits synaptogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Cell projection, dendrite.
Protein: YNS4_YEAST
Sequence: MKRVTLIVLPRRQFPFLKFHSKEALESAVNLQLIRRKKSVNIQIDSVTFCIYFCLLYFRTLEYHRGTISLHNVTGSKKRDSKANSRSRPSGTITSRGARIGLQGYKSH
What are the official names of this protein?
Uncharacterized protein YNL184C.
Protein: RUVC_COXBN
Sequence: MDNPRRIIIGIDPGSRITGYGIIWSQGSKQGCIAFGQIKTDNDSLNFRLHQIERELRDLILIHRPHEAAIEQVFTFHNHQSALKLGQARGAALVATAACALPVAEYSARQIKQAVVGYGAATKAQVQHMVHLLLQLEKAPPADAADALAIALCHATSSRLSEKLMQAKGTLT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PYRDB_BACFR
Sequence: MADLSVNIGKLQMKNPVMTASGTFGYGEEFADFIDITRIGGIIVKGTTLHKREGNPYPRMAETPSGMLNAVGLQNKGVEYFSNHIYPRIKDIQTHMIVNVSGSAIEDYVKTAEIINELDKIPAIELNISCPNVKQGGMAFGVTTKGVSEVVQAVRSAYKKTLIVKLSPNVTDIAEMARAAEANGADSVSLINTLLGMAIDAERKRPILSTVTGGMSGAAVKPIALRMVWQVAKAVNIPVIGLGGIMNWKDAVEFMLAGASAIQIGTANFIDPAITIKVIDGINDYLERHGCKSVSEIIGALEV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERM1_CLOPF
Sequence: MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIPYHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTVTYEQVLSIFNSYLLFNGRK
What is the function of this protein?
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.
What are the official names of this protein?
rRNA adenine N-6-methyltransferase, Macrolide-lincosamide-streptogramin B resistance protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: UBIE_RICRO
Sequence: MNQTNFGFKKVDYTKKQGLVNNVFSNVADKYDLMNDLMSLGLHRLWKDEFIRQIPNLNSHILDVASGSGDIALKLAKKARDRVNNISLTLSDINEEMLKQAKKKAIDLNLFQNLKFTVASAEELPFPDDSFDYYTIAFGIRNVPDINKALKEACRVLKPMGKFICLEFSKVKEGYIKDFYKFYSFNIIPSIGQMIAGNKEAYEYLVESIDLFPSQDEFRIMIKDAGFEEVGYKNLSGGIVAIHSAYTR
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: COG2_SCHPO
Sequence: MTEKDADSGSDLVDAFLSDAYLNTEELRKDGPFSPDEFLVSKRFLGLDGLVNELSRLFEQVNNELMLLVKDNYQDFVHLGSRMKSGNTKVSTLISSIHRSEEQLKNSKQSLIGHSTEIQNNLKHKQDVENEKLIASNLLLLDQILKFLKSNDSSHPLWLESLNNAQRLCDTYKDHPWVQSISPTLINYIKH
What is the function of this protein?
Required for normal Golgi morphology and function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 2, COG complex subunit 2, Component of oligomeric Golgi complex 2.
What is the protein family that this protein belongs to?
Belongs to the COG2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus.
Protein: HTPG_PSEMY
Sequence: MSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFEALAKPELLEGGAELKIRLSFDKDAKTVTLEDNGIGMSRDEVIAHLGTIAKSGTADFLKNLSGDQKKDSHLIGQFGVGFYSAFIVADKVDVFTRRAGLSAAEGVHWSSKGEGEFEVATVEKAERGTRIVLHLKSGEEEFADGWRLRNIVKKYSDHIALPIELPKEHYGEEKDKPAEVEWETVNRASALWTRPRAEVKDEEYQEFYKHVAHDFENPLTWSHNKVEGKLEYTSLLYVPGRAPFDLYHREAPKGLKLYVQRVFIMDQADEFLPLYLRFIKGVVDSNDLSLNVSREILQKDPVIDSMKSALTKRVLDMLEKLAKDKPEEYKAFWKAFGQVLKEGPAEDFANKEKIAGLLRFASTAGEGDEQSVSLADYLGRVKDGQDKIYYLTGESYAQIKNSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTEFDGKQFVDVARGDLDLGKLDSEEDKKAQEEVAKAKEGLIERLKGALGEQVKEVRVSHRLTDSPAILAIGEQDLGLQMRQILEASGQKVPESKPIFEFNPSHPLIERLDAEADEDRFVDLTHILFDQAALAAGDSLKDPAAYVQRLNKLLVELSA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_VIBC1
Sequence: MKVGIIGAMEQEVTILKEAMTNCQTVSKAGCTFFSGQINGVDVVLLQSGIGKVAAAVGTTILLDEYQPDVVINTGSAGGFDSSLNLGDVVISTEVRHHDTDVTAFGYEMGQMAGQPAAFKADEKLMDLAEKALAQMENTHAVRGLICTGDAFVCTAERQEFIRKHFPSVIAVEMEASAIAQTCHQFNTPFVVVRAISDVADKESPMSFEEFLPLAAKSSSEMVCKMLELTK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: GCH1_ACTP2
Sequence: MSIISAEAQKVREALIAKGIETPTVQLTKDKDSRRAEIQQHMRSVLELLGLDLQDDSLEETPHRLAKMYVDEIFSGLDYATFPKITNIENRMKVSEMVLVDDITLTSTCEHHFVTIDGKVAVAYYPKKWVIGLSKINRVVQFFAQRPQVQERFTEQILTAFQTILETDDVAVFVKATHFCVKCRGVKDTNSYTVTSAFGGVFLEDRETRKEFLGLINK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: FADI_YERPY
Sequence: MSKPLPLVTRQGDRIVIVNGLRTPFAKQATAYHGVPAVDLGKIVVSELLARSGISSELIDQLVFGQVVQMPEAPNIAREIVLGTGMSVHTDAYSVSRACATSFQAVANVAESIIAGSVDIAIAGGADSSSVLPIGVSKALARTLVDANKARSLSQKLKLFSRLRLRDLLPVAPAVAEYSTGLRMGDTAEQMAKTYGISREDQDALALRSHQLAAEAWQQGWLHDEVMTAYIPPYREAIIEDNNIRKDSTLAQYAKLRPAFDRQHGSVTAANSTPLTDGAAAVLMMSESKAKALGLPPLGYLRSFAFSAIDVWQDMLLGPSYATPLALDRAGITLADLTLIDMHEAFAAQTLANLKMFASDTFAREKLGRSQAIGEVDMSKFNVLGGSIAYGHPFAATGARMITQTLNELRRRGGGLGLTTACAAGGLGAAMILEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.