PharMolix/UniProtQA huggingface dataset:
Protein: RSMF_SALNS
Sequence: MAQHAVYFPDAFLTQMREAMPSTLSFDEFISACQRPLRRSIRINTLKISVADFLALIAPYGWSLTPIPWCHEGFWIERDDEEALPLGSTAEHLSGLFYIQEASSMLPVAALFADDNHPQRVMDMAAAPGSKTTQIAARMGNRGAILANEFSASRVKVLHANISRCGIANTALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNLDIAATQRELLDSAFHALRPGGTLVYSTCTLNRQENEAVCLWLKETYADAVEFLPLGDLFPDADRALTPEGFLHVFPQIYDCEGFFVARLRKMSSLPAMPAPGYKVGAFPFTPLKGREALHVTQAANAVGLLWDENLHLWQREKEVWLFPAEIESLIGKVRFSRLGIKLAESHNKGYRWQHEATIALACPTHAHAFELSVQEAEEWYRGRDIYPQTPPAADDVLVTFQHQPLGLAKRIGSRIKNSYPRELVRDGKLFTGNS
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_SHEB2
Sequence: MRILAKWLALAVLLCTTPAKAALDIVITEGVDAARPIAVMPFVWQGPGAAPQAIADVVMSDLVRSGTFKPLDELGLPQRNIGTAAQFQANSWSSVGAEALVLGTVKPYGTDQYLVSFDLIDLVKAQNQALKGPVSATEFLMDSRQTVISAAQFRQYGHRISDIVYEKLTGIRGAFLTRISYVVVNHTQKAPYQLMVADYDGVNEQMLLRSPEPLMSPTWSPDGRRLAYVSFENKKAEIFVQDLYTQVRTKVSSFPGINGAPAFSPDGKSLAITLSKDGQPEIYIIDIATKAIKRITNHYAIDTEPSWYPDGKSLIFTSERGGRPQIYRVELSSGKVSRETFEGEWNLGGSITPDGRSMIFVNRTNGKFNIARMDLSTRFMQVLTSTRLDESPSVAPNGTMVIYGTTYQGKQVLAAVSTDGRFKARLPAGQGEVKSPSWSPFL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NODG_RHIME
Sequence: MFELTGRKALVTGASGAIGGAIARVLHAQGAIVGLHGTQIEKLETLATELGDRVKLFPANLANRDEVKALGQRAEADLEGVDILVNNAGITKDGLFLHMADPDWDIVLEVNLTAMFRLTREITQQMIRRRNGRIINVTSVAGAIGNPGQTNYCASKAGMIGFSKSLAQEIATRNITVNCVAPGFIESAMTDKLNHKQKEKIMVAIPIHRMGTGTEVASAVAYLASDHAAYVTGQTIHVNGGMAMI
What is the function of this protein?
Proposed to modify Nod factor fatty acyl chain.
What are the official names of this protein?
Nodulation protein G, Host-specificity of nodulation protein C.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MUTS2_ANADF
Sequence: MTDRTQRELGWPEILNALAARCRLPAGRNRALALPFQPTAEAAREALALVGEARRLSELALALPLGGVGDVEGHLERASKGGVLEPLALRECAALARAAARTRGLLEARASETPRLWALAEPLSPSAALADRIERAIEPSGAISDRASAELAQARERSRGLHRALKAQVETLLADADMQRHLRDTYFTIRNERYVLPVLASARRAVPGIVHNASQSGQTLFVEPDSMVELGNELSIANAVAAEEEQRILRELTGALMADSGALARDLGILAALDVLEGSALLASDLDAHAPEVLSPFDGLRVGGAGAGFELLSLRHPLLVLQGKKVVPSHVRLDAPARALIVSGPNGGGKTVAITAVGLSALMLRAGLPVAAAEGSRLPFFLEVKAAVDERGDLAKDLSTFTAHLAAVKEMLAGAVPGSLILVDEIAADTDPREGAALAAAILESLVERGAAVLVTTHLDELKALALTDPRYANARVGFDAERLAPTYQLHLGSPGSSSAIEVAARVGLPAPLVERARAALTGHGGALGQALRALDDERARLAEERRAAESARDAARKAEERARAAEEVARRAQREAAARMGEALADELEAARAEVAELLAGLQARPTVKAATDAARQLDAWRATVAQAAKATQARADAGAEALPGGEVRPGVRVRIVSLGQEGEVVEVDGKDALVRAGPLKVRRPVADLVPLLGKAKDAAKLGRSRSEKLQAASEARPSAPPGLERRLDVRGLRVEELLREVERFLDRLYSDGEADCLILHGHGTGALKQALRDHLSASPYVGAFRAGDRHEGGDAVTVVSLRR
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: PANC_LARHH
Sequence: MDIIRTIEEMRSWRQKAGRVALVPTMGNLHEGHLALVREAKKQAERVVVSIFVNRLQFGQGEDFDSYPRTFEADRDKLAAAGVDALFLPDERELYPRIRQDFNVEPPHIQDELCGAFRPGHFRGVATVVTKLFNIVQPDAACFGKKDFQQLHIIQAMVADLNQPVKVVPVDIGRAADGLALSSRNGYLSAGEREEAPRLFRELSRIRENLIDGENDYASLEQDARATLEQHGWRVDYVEIRQADTLELAHAGEKRLVVLAAARIGKTRLIDNVEIFR
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_RHOP5
Sequence: MAQRSQQASPPPNLAADKAAALRLTPVSRETESRLDAYVALLLQWQAKTNLISPATLPQLWTRHIADSLQLLTVAPDARTWLDFGSGGGFPGVVLACAMAELGGSVTLVERNAKKAAFLREALRVSGGVGQVILADIGDSVDRFPPHIDCITARAVAPLHQLIGFAEPLLHRGGKALFLKGQDVEAELTEAAKYWRLQPRLHASLTGGQGWIVELDRIERQSATTINGTRA
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNP1_HALSA
Sequence: MTTITPESLPRHELLGLHARVAADTDQSRVGIAGRVVDETMQTVVLRTASGVAQVPKKGATFEFRLTDEAAAPDNGVGTAFKPAGGETRQTTGESVAYVTVDGGRLLSRPERRSENGVDSKWR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_ERYLH
Sequence: MPGLLLDTLNRTRSDRVPLWLMRQAGRYLPEYRELRARKGGFLELVYDSEAAREVTLQPIRRFGFDGAILFSDILIVPHALGQKLEFLAGEGPHLSPRLADAELEALSTVPERLDAIYETVRQVRAALDPETTLLGFAGSPWTVATYMVAGEGSRDQQAARSMAYTDPGKLQAIVDAIIDLTVEYLVGQIDAGAEAVQLFDSWAGSLAPDQFERWVIAPNAAIVRRLKEARPDALVIGFPKGAGAKLSAYAAGTGVDAIALDETIDPAWAHTVLPDGMPVQGNLDPLQILAGGDAMVERTKAILGALADRPHVFNLGHGIDKHTPIGHVERLVDTVRNWQR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_METMP
Sequence: MAEQVVEILVSGGKATAGPPLGPAIGPLGVNIMQVVQKINNMTKDYEGMSVPVKVIVDTDKRTFEVEVGIPPASALIKKEIGIEKGSQEPKHQVAGNITMEQIVKIAKMKQDAMLAYNLKNASKEVVGTCVSVGISVEGMTPSEAQKAIDAGQFDSYFN
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NCAP_HRSVA
Sequence: MALSKVKLNDTLNKDQLLSSSKYTIQRSTGDSIDTPNYDVQKHINKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTIKILRDAGYHVKANGVDVTTHRQDINGKEMKFEVLTLASLTTEIQINIEIESRKSYKKMLKEMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLTAVIRRANNVLKNEMKRYKGLLPKDIANSFYEVFEKHPHFIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGAGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPHFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKENGVINYSVLDLTAEELEAIKHQLNPKDNDVEL
What is the function of this protein?
Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases (PubMed:23677789, PubMed:19965480, PubMed:31229488).  RNA replication depends on the availability of soluble nucleoprotein (PubMed:9299631, PubMed:22623798).  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication (PubMed:22623798).  Together with the phosphoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway (PubMed:32878896).  May also act as a modulator of the innate immune response by sequestration of host IFIH1/MDA5 and MAVS into IBs (PubMed:22623778).
What are the official names of this protein?
Nucleoprotein, Protein N, Nucleocapsid protein.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Localizes in cytoplasmic inclusion bodies.
Protein: YR527_MIMIV
Sequence: MGVLEFFGTLLRNDITASSIMSDYKNKLPVNHLLMDFNSIVHVASQKIISDVNSFMQNVLTNLYQNRSLNTTLLNEQFTKYKMQHIQKRINNNTDPIEITKLFNNHFDDKFMDRLIITLVISVLLSIIRTYCTNETMKTLLIAIDGVPSKGKMIEQKQR
What are the official names of this protein?
Uncharacterized protein R527.
Protein: NUOK_NITEU
Sequence: MVSLSHYLVLGALLFAIGVVGIFLNRKNVIILLMSIELMLLAVNMNFVAFSHFLQDTAGQIFVFFILTVAAAEAAIGLAILVALFRNLRTINVDDLDELKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PUR1_MYCTO
Sequence: MAVDSDYVTDRAAGSRQTVTGQQPEQDLNSPREECGVFGVWAPGEDVAKLTYYGLYALQHRGQEAAGIAVADGSQVLVFKDLGLVSQVFDEQTLAAMQGHVAIGHCRYSTTGDTTWENAQPVFRNTAAGTGVALGHNGNLVNAAALAARARDAGLIATRCPAPATTDSDILGALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDENTLYACRDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLAIDADGVRSTRFANPTPKGCVFEYVYLARPDSTIAGRSVHAARVEIGRRLARECPVEADLVIGVPESGTPAAVGYAQESGVPYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRGNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVENEDEMLEAVRHAIGADTLGYISLRGMVAASEQPTSRLCTACFDGKYPIELPRETALGKNVIEHMLANAARGAALGELAADDEVPVGR
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPATase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: CYSG_ECOSE
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMSERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: SYW_STRPN
Sequence: MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLADQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLVSLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIEQTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDADTLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLGDVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGAMGLHYFN
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_XANOM
Sequence: MANIKSAKKRAKQTIVRNERNTGQRSMLRTAVKKVIKALDANDAAGAEAAFAVAQPILDRFSARGLIHKNKAARHKSRLTARIKAIKAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RNY_THEP1
Sequence: MLWYIVAGAGGLLIGYLIASYQINQKLRKAKEDAQTIIEKAEKEANEIKKKAIIEGREEVHRLREEFEKERSRREEELRAFEERILKREELLTRKEENLEKREHQIEELKANLEEKMREVEEKEKRIDEELKRLAGMTVEEARELILEEARQRYEHDLAKLYKEMKEQVEEEVEKEAKKVIAFAVQRYAPDYVGEITVSTVSLPSDDMKGRIIGREGRNIRTFEKITGVDLIIDDTPEVVVLSCFNPLRREIARITLEKLVADGRIHPARIEEMYEKAKQEVEKAIKEAGQEATFKAGVMGLHPELVKLLGKLKYRTSYGQNVLNHSIEVALLAGYMASELGLNADKARRGGLLHDIGKAVDQELEGSHTTIGAELARRYGEKEDIINMILSHHGEEEPMTPEAVLVAAADALSAARPGARRESLENYIKRLMKLEEIAKSFKYVEKAYAIQAGREIRVIVEPDKVDDALAEKLAYDISKKIEEELEYPGVLKVVVIREKRSVAYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NDUS8_RECAM
Sequence: MTIINKTAQTLFLTELVKGMSLTLDYFFRKKVTLNYPFEKGPLSPRFRGEHALRRYQTGEERCIACKLCEAICPAQAITIESEPRIDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETHEELLYDKEKLLQNGDRWETEIAANLANEALYR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).  May donate electrons to ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SELO_SPHAL
Sequence: MQFAFDNSFHADMQGFYAPAEAAKPSAPRLLAFNDALAERLGFDRRGVDADELARVFSGEELPEGAAPIALAYAGHQFGHFSPQLGDGRALLLGEIVAPDGARFDIQLKGSGPTAFSRGGDGKAAIGPVLREFLVSEAMAAMGVPTTRALAAVTTGERVERERAHPGAVLTRVASSHIRVGTFQFFAAHFGADHVVQLSDYSIARHFPDLADAANPHLALLDRVIGLQCALIARWLGVGFIHGVMNTDNVAISGETIDYGPCAFMDRFAANTVFSSIDATGRYAYGRQPQIMHWNMARFAEALLPAIHRVSPADVEAAKALVDAIPGRFRAAWHAQVREKLGLSTSAGDDAELIDRLFDELEKHSVDFTTFFRALAMLLRGEGAMMQALLPAPDAMAPWIADWWQRIEQDAANPLDLADAMDAVNPLYIPRNHRVEAALEAAEAGDPAPWLELLEVVRQPFAARAGRERFAEPAPADAAPYTTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: MUP_RAT
Sequence: MKLLLLLLCLGLTLVCGHAEEASSTRGNLDVAKLNGDWFSIVVASNKREKIEENGSMRVFMQHIDVLENSLGFKFRIKENGECRELYLVAYKTPEDGEYFVEYDGGNTFTILKTDYDRYVMFHLINFKNGETFQLMVLYGRTKDLSSDIKEKFAKLCEAHGITRDNIIDLTKTDRCLQARG
What is the function of this protein?
Major urinary proteins (Mups) bind and release pheromones.  They may also protect pheromones from oxidation.  In this context, they play a role in the regulation of social behaviors, such as aggression, mating, pup-suckling, territory establishment and dominance.  Acts as a kairomone, detected by the prey vomeronasal organ and inducing fear reactions in mice.
What are the official names of this protein?
Major urinary protein, MUP, Allergen Rat n I, Alpha(2)-euglobulin, Alpha-2u-globulin, alpha-2u globulin PGCL1.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
[15.5 kDa fatty acid-binding protein]: Cytoplasm, cytosol. Note=It is probably taken up from the urinary lumen by endocytosis. SUBCELLULAR LOCATION: Secreted.
Protein: COX8A_MACSL
Sequence: MSVLTSLLLRGLTGSARWLPVPRAKVHSMPPEVELGIMEKAIGLTSCFVSLFLPAGWILSHLEDYKRPE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8A, mitochondrial, Cytochrome c oxidase polypeptide VIII-liver, Cytochrome c oxidase subunit 8-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DNCH_MICAN
Sequence: MPYERLIYLADTDAAGVVYFAHLLSICHEAYEFSLAQFGINIKDFFKDSPVALPITQAEIQFFRPLFCGDRIQIDFTVRSLSENEFQLQYKIYLAEIMVAKAKTRHVCIAPTARKRIPLPESLKHWLGYLSTLEETGI
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Protein: DCUP_STAAM
Sequence: MVHNKNNTILKMIKGEETSHTPVWFMRQAGRSQPEYRKLKEKYSLFDITHQPELCAYVTHLPVDNYHTDAAILYKDIMTPLKPIGVDVEIKSGIGPVIHNPIKTIQDVEKLSQIDPERDVPYVLDTIKLLTEEKLNVPLIGFTGAPFTLASYMIEGGPSKNYNFTKAMMYRDEATWFALMNHLVDVSVKYVTAQVEAGAELIQIFDSWVGALNVEDYRRYIKPHMIRLISEVKEKHDVPVILFGVGASHLINEWNDLPIDVLGLDWRTSINQAQQLGVTKTLQGNLDPSILLAPWNVIEERLKPILDQGMENGKHIFNLGHGVFPEVQPETLRKVSEFVHTYTQR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_ECO24
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS10_CAUSK
Sequence: MDRQNIRIRLKAFDHRVLDHSTREIVNTAKRTGATVRGPIPLPTLIEKFTVNRSPHVDKKSREQFEIRTHKRVLDIVDPTPQTVDALMKLDLSAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RPOC_AQUAE
Sequence: MSEARRGIFPFSKIKLMLASPEDIRSWSHGEVKRPETLNYRTLKPEKDGLFCAKIFGPIKDYECLCGKYRGKRYEGKICEKCGVEVTTSYVRRQRFGHIELAAPVVHIWFLKSTPSKIGTLLNLTSRDVERVAYFESYLVIEYPNEEEEEKFEKDEHTIPLNDGISTKWVKLHVVNEEEFEEKYAFTIDEKYEHGMGAEILKEVLSKLDLDAYSRKLKEIVKPYSIGFEDLGKEIEQKYKNLYQKLIKVIADDFRAYGVEIKGLEDHGLSLEQAIHRILNEELYLNVETGEISLEDCGDSCLTGRDALKEYYERVREHKKDIPIFEKIKEDIRSTVLREISEARIRKALRTLQLVEGFKKSGNRPEWMILEVLPVLPPELRPLVALDGGRFATSDLNDFYRRVINRNNRLKRLIELNAPDIIIRNEKRMLQEAVDALIDNGKRGNPVKQNGRPLKSLADYLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELQMHQCGLPKIMALELFKPFVYRRLEEKGYATSIKHAKRLVEQKTPEVWECLEEVVKEHPVLLNRAPTLHRPSIQAFEPVLVEGKAIQLHPLVCPPFNADFDGDQMAVHVPLGIEAQLESYILMLSTQNVLSPAHGKPLTMPSQDMVLGTYYITHDPIPGRKGEGKAFGTFEEVLKALELGHVDIHAKIKVKVGNEWIETTPGRVLFNSIMPEGQPFVNKTLDKKGLSKLITELYIRVGNEETVKFLDRVKELGFLRSTLAGISIGVEDLQVPKAKKKIIEEALKKTEEIWNQYVQGIITNKERYNRIIDVWSEATNLVSKAMFEEIEKSKRIENGKEYPGTFNPIYMMAISGARGNRDQIRQLAGMRGLMAKHSGEFIETPIISNFREGLSVLEYFISTYGARKGLADTALKTAFAGYLTRRLVDVAQDITITERDCGTVKGFEMEPIVEAGEERVPLKDRIFGRVLAEDVKDPYTGEIIARRNEVIDEKLAEKITKAGIEKVRVRSPLTCEAKHGVCAMCYGWDLSQRKIVSVGEAVGIIAAQSIGEPGTQLTMRTFHIGGAATAQKVQSFVKAESDGKVKFYNVKLIVNRKGEKINISKDAAIGIVDEEGRLLERHTIPYGARILVEEGQEVKAETKLADWDPFNTYIIAEVGGKVELRDIILDVTVREERDPITGKTASVISFMRPRDAMLHTPRIAVITEDGKEYIYDLPVNAILNIPPEKISLEWRVCPTCSESEETTIQHQYYVVKDLEVQPGDILARIPKETAKVRDIVGGLPRVEELFEARKPKNPAILSEIDGYVKIYEDADEVIIFNPRTGETAKYSIKKDELILVRHGQFVKKGQKITETKVAEIDGQVRIKGRGFKVIVYNPETGLQREYFVPKGKFLLVKEGDFVKAGDQLTDGTPVPEEILRIKGIEELEKFLLKEVQMVYKLQGVDINDKHFEIIIKQMLKKVRIIDPGDSRFLVGEEVDKEELEEEIQRIKLEGGKLPKAEPVLVGITRAALSTRSWISAASFQETTRVLTDASVEGKIDELRGLKENVIIGNIIPAGTGVDEYREVDVIPAEEKVLEEKKEPKEGS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RL22_PYRIL
Sequence: MPQHQNYSLSEEDVIQLVFRKYGVKITSEQIVRAYAPEQKMSWKKSVEVARFIKGMTLRQAKSWLEDVVKMKRPIPIKTFKKKQAHHAVPWSGWPVAKWPVKVAKRFLDLLENLENNAKFRGLDVERVVIVHAAAHKGYRIPNIMPRAFGRATRFDEQTVNVEVIAAELPKEVVPKRYKLNLVKR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PYRH_STRPQ
Sequence: MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSGVQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQTAIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMAKNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMNEAGNIQRVVFGEHIGTTVSNKVCD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.