PharMolix/UniProtQA huggingface dataset:
Protein: LARP7_XENTR
Sequence: MTAIETDTPSNKVKEDESTDLRKDREKKKRSRVKQLLADIAKQVDFWFGDVNLHKDRFLREQIEKTRDGYIDISLLASFNKMKKITTDSKLIARAVKNSSVVEINLSGTKIRRRFPLGEKPQDVDSRTVYVELLPKNVTHSWIERVFGKYGMVVYVSIPRYKSTGDPKGFAFIEFETQEQAAKAIEVLNNPPEEAPRKAGMFPKTVKNKHLPPVEVTEHSITEGCGTEEKKKKKKKKSKARKDSVEKAEEDTKEQDMDIISEGVPKRRKTVSESSVPDVQEADKQTAKKEKKKKERAESFDQSEKVRQGKRKCSSSEEHDCSSAKQKKSDTKDLPQDEKPMVTQEVLQECKELSTEEEKDAVDKKEISVPKVKRKRKKKHKERHRVGEEVIPLRVLSKTEWLVLKAEYLTLQRASMASLKKSMSEMNHISEEEMQTQPSMQSFDIKNGKVETVKNEPLGPQFVCGVIGKITSSDPLQGRKYVKDAFSGVCEVVYVDMLEGDTECHVRFKSPEDAQTAVKTRSDLQGKHNWKLQILAGDNEQRYWQKILVDRQAKLNRPREKKRGTEKLIAKAEKMRLAKTQEASKHIRFSDGF
What is the function of this protein?
RNA-binding protein that specifically binds distinct small nuclear RNA (snRNAs) and regulates their processing and function.  Specifically binds the 7SK snRNA (7SK RNA) and acts as a core component of the 7SK ribonucleoprotein (RNP) complex, thereby acting as a negative regulator of transcription elongation by RNA polymerase II.  The 7SK RNP complex sequesters the positive transcription elongation factor b (P-TEFb) in a large inactive 7SK RNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (By similarity).  The 7SK RNP complex also promotes snRNA gene transcription by RNA polymerase II via interaction with the little elongation complex (LEC).  LARP7 specifically binds to the highly conserved 3'-terminal U-rich stretch of 7SK RNA; on stimulation, remains associated with 7SK RNA, whereas P-TEFb is released from the complex.  LARP7 also acts as a regulator of mRNA splicing fidelity by promoting U6 snRNA processing.  Specifically binds U6 snRNAs and associates with a subset of box C/D RNP complexes: promotes U6 snRNA 2'-O-methylation by facilitating U6 snRNA loading into box C/D RNP complexes.  U6 snRNA 2'-O-methylation is required for mRNA splicing fidelity (By similarity).
What are the official names of this protein?
La-related protein 7, La ribonucleoprotein domain family member 7.
What is the protein family that this protein belongs to?
Belongs to the LARP7 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: NATD1_DANRE
Sequence: MAQAAQINVLDISTRLRVEHDKKRRQFSIRLNGSHDKAVLLYEYVGKKTVDLQHTEVPEAYRGREIAKHLAKAAMDFVVEEDLKAHLTCWYIQKFVKENPHPQYLERILH
What are the official names of this protein?
Protein NATD1, N-acetyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the NATD1 family.
Protein: RBFA_STRA5
Sequence: MKKGLIMANHRIDRVGMEIKREVNEILRLRVNDPRVQDVTITDVQMLGDLSMAKVFYTIHSTLASDNQKAQIGLEKATGTIKRELGKNLTMYKIPDLQFVKDESIEYGNKIDEMLRNLDKKD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSNA_ECOLI
Sequence: MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDASFKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPDFISTLKNLWWRLDRALDEESLYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRDAFLKVGLRAMTCFETTDRNNGIKELQEGVEENIRFARLIDEAKKATSEPYLVEAHIGAHAPFTVPDAGLEMLREAVKATGRGLHIHAAEDLYDVSYSHHWYGKDLLARLAQFDLIDSKTLVAHGLYLSKDDITLLNQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFEEMKFAFFKHRDAGGPLWPDSFAKALTNGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIAFGMGSGSVHSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA
What are the official names of this protein?
Putative aminohydrolase SsnA.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
Protein: NAGB_BACFR
Sequence: MRLIIQPDYQSVSQWAAHYVAAKIKAANPTPEKPFVLGCPTGSSPLGMYKALIDLNKKGIVSFQNVVTFNMDEYVGLPKEHPESYYSFMWNNFFSHIDIKPENTNILNGNAADLDAECARYEEKIKSYGGIDLFMGGIGPDGHIAFNEPGSSLSSRTRQKTLTTDTIIANSRFFDNDINKVPKTSLTVGVGTVLSAREVMIIVNGHNKARALYHAVEGAITQMWTISALQMHEKGIIVCDDAATAELKVGTYRYFKDIEADHLDPQSLLK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: Y653_METJA
Sequence: MKIACDIPVSEVMSFPVIKATKNMSIYDIANIMTENNIGAVVIVENNKPIGIVTERDIVKRVVSKNLKPKDVLAEEVMSKKIITIPQNASITEAAKIMATHGIKRLPVVKDGELVGIVTQSDIVRVSPELLEIVIEYASITPEEKEVISLDTDEFSEEYINGICENCGYQGRVRLYQGRYLCDECIEEFEEKEE
What are the official names of this protein?
Uncharacterized protein MJ0653.
Protein: ACCD_BACAC
Sequence: MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPKCKKIMYTKEVLKNLKVCVNCGYHHPMNAWERLDSILDEGSFREYDKEMVSLNPLEFPNYEEKLESDRKKTELNEAVVTGEGTIDDMLVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFIIFTASGGARMQEGILSLMQMAKTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVREKLPEDFQTAEFLLEHGQLDAVVHRDDMRESLRKILEVHQGGEMAVWQS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_COXBR
Sequence: MLRLKNDRFIRALLRQPVDRTPVWIMRQAGRYLPEYRQLREKVPNFMAFCKTPELACEATLQPLRRFPLDAAIIFSDILTIPDAMGVDLHIAPTVGPVIRNPVRSAQDVNRLQMPAVEEALSYLFDAIRLTVKALDHRVPLIGFAGSPWTLACYMTEGQSSKTFLTARAMLYQQPDVFHTLLQKLTTLTIAYLNAQIKAGADVVMLFDTWGGLLTPSLYRQFSLDYLSQIAAEVVRQKNGRKIPLIFFTKNGGQWLESIANSGCDAVGLDWTTDIGQARRRVGDRVALQGNLDPAILLSNPESISTAAVDILKSYGQGSGHVFNLGHGIDPSTPIENVAALVEAVQNFSIKNEKPISSYYR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSDME_HUMAN
Sequence: MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPKYQFLSLTLGDVLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETALGKVKLNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCALGREHS
What is the function of this protein?
Pore-forming protein produced by cleavage by CASP3 or granzyme B (GZMB), which converts non-inflammatory apoptosis to pyroptosis or promotes granzyme-mediated pyroptosis, respectively (PubMed:27281216, PubMed:28459430, PubMed:32188940, PubMed:33852854, PubMed:35594856).  After cleavage, moves to the plasma membrane, homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, allowing the release of mature interleukins (IL1B and IL16) and triggering pyroptosis (PubMed:28459430, PubMed:32188940, PubMed:33852854, PubMed:35594856).  Binds to inner leaflet lipids, bisphosphorylated phosphatidylinositols, such as phosphatidylinositol (4,5)-bisphosphate (PubMed:28459430).  Cleavage by CASP3 switches CASP3-mediated apoptosis induced by TNF or danger signals, such as chemotherapy drugs, to pyroptosis (PubMed:27281216, PubMed:28459430, PubMed:32188940).  Mediates secondary necrosis downstream of the mitochondrial apoptotic pathway and CASP3 activation as well as in response to viral agents (PubMed:28045099).  Exhibits bactericidal activity (PubMed:27281216).  Cleavage by GZMB promotes tumor suppressor activity by triggering robust anti-tumor immunity (PubMed:21522185, PubMed:32188940).  Suppresses tumors by mediating granzyme-mediated pyroptosis in target cells of natural killer (NK) cells: cleavage by granzyme B (GZMB), delivered to target cells from NK-cells, triggers pyroptosis of tumor cells and tumor suppression (PubMed:32188940, PubMed:31953257).  May play a role in the p53/TP53-regulated cellular response to DNA damage (PubMed:16897187).
What are the official names of this protein?
Gasdermin-E, Inversely correlated with estrogen receptor expression 1, ICERE-1, Non-syndromic hearing impairment protein 5.
What is the protein family that this protein belongs to?
Belongs to the gasdermin family.
What are the subcellular locations of this protein?
[Gasdermin-E, N-terminal]: Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Gasdermin-E]: Cytoplasm, cytosol.
Protein: POM33_CHATD
Sequence: MAPPPPSADVPLAERLQRLASTLQFAWFSGHALLLLCVFRYAFSWIRFNYYSGMARFCYRFAFIAAAATYGIVVYKTWRARQKTGVKTSGIKDYLRDENIQYLVLALVWLFMPQYPLALLPYGIYSVFHVATYVRANLIPTLVPPQRINAPAGASPNAKPQYTQHPASEAIGVFVKKYYDSSMSMVARLEIMLWLRLILSVILFQRRSWILFAIYTTFLRTRFSQSIHVQNAFALLEARIDNLIGAQGTPPQARQVWDNVKTAARQFYAVTDLNKYESGVAAPKKSS
What is the function of this protein?
Contributes to proper distribution and/or efficient assembly of nuclear pores.
What are the official names of this protein?
Nucleoporin POM33, Nuclear pore protein POM33, Pore membrane protein of 33 kDa.
What is the protein family that this protein belongs to?
Belongs to the PER33/POM33 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Nucleus, nuclear pore complex.
Protein: RL25_SALA4
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGSEAPIAIELDHDQVMNMQAKAEFYSEVLTLVVDGKEVKVKAQAVQRHAYKPKLTHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: AHLLM_AGRFC
Sequence: MTDIRLYMLQSGTLKCKVHNIKMNQGNGADYEIPVPFFLITHPAGHTVIDGGNAIEVATDPRGHWGGICDVYWPVLDKDQGCVDQIKALGFDPADVKYVVQSHLHLDHTGAIGRFPNATHIVQRSEYEYAFTPDWFAGGGYIRKDFDKPGLKWQFLNGAQDDYYDVYGDGTLTTIFTPGHAPGHQSFLVRLPNSKPLLLTIDAAYTLDHWEEKALPGFLASTVDTVRSVQKLRTYAEKHDATVVTGHDPDAWANFKKAPEFYA
What are the official names of this protein?
N-acyl homoserine lactonase AttM, AHL-lactonase AttM.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: DER_MYCBP
Sequence: MTQDGTWVDESDWQLDDSEIAESGAAPVVAVVGRPNVGKSTLVNRILGRREAVVQDIPGVTRDRVCYDALWTGRRFVVQDTGGWEPNAKGLQRLVAEQASVAMRTADAVILVVDAGVGATAADEAAARILLRSGKPVFLAANKVDSEKGESDAAALWSLGLGEPHAISAMHGRGVADLLDGVLAALPEVGESASASGGPRRVALVGKPNVGKSSLLNKLAGDQRSVVHEAAGTTVDPVDSLIELGGDVWRFVDTAGLRRKVGQASGHEFYASVRTHAAIDSAEVAIVLIDASQPLTEQDLRVISMVIEAGRALVLAYNKWDLVDEDRRELLQREIDRELVQVRWAQRVNISAKTGRAVHKLVPAMEDALASWDTRIATGPLNTWLTEVTAATPPPVRGGKQPRILFATQATARPPTFVLFTTGFLEAGYRRFLERRLRETFGFDGSPIRVNVRVREKRAGKRR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CRVP2_PSEPL
Sequence: MIVFILLSLAAVLQQFVADVNFESESPRRTEKQTEIVDMHNSFRRSVNPTARNMLKMEWYPEAADNAERWAYQCIYDHSANSERVIGGIQCGENIYKSSNPRAWTEIIQSWYDEIQNFEYGVGANPPGSVIGHYTQIVWYKSYRIGCAAAYCPSYPYNYFYVCQYCPTGNMEGLTATPYTSGPTCADCPSHCDDGLCTNPCPITNTFTNCDSLLQQNSCEDSYIKTNCGASCFGQDK
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein ENH2, CRVP, Cysteine-rich secretory protein ENH2, CRISP-ENH2.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: PELO_SULIN
Sequence: MRILEFDEKRQAAKLHIESEDDLWILHLILEKGDKVVAKTTRDIGLGKESRRIPMTIVLKVDYTEFQEFTNRLRIHGIIEDAPERFGIRGAHHTINLDIGDEIIIIKQQWNKYALDKLKKQADKRSKIIIALVDFDEYLIAIPFEQGIKILSEKSLRSLNEEEGIIEQNALEVATELAEYVKQYNPDAILLAGPGFFKEEVAKKVNNILKNKKVYIDSVSSATRAGLHEILKRDIIDKIMSDYEIAIGAKKMEKAMELLAKQPELVTYGLEQVKNAVEMGAVETVLLIEDLLSSNNQERLAIERILEDIENKRGEIILVPKESPIYFELKNLTGILAILRFRIN
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_STAES
Sequence: MSYKIVALPGDGIGPEILSGTLELLKLISEKYHFEYHLESHHFGGVSIDYYGTPLTNETLQSCKNADAILLGAIGGPKWTDPNNRPEHGLLKLRKSLNLFANIRPTFVTKGASHLSPLKQDIVEGTDLVIVRELTSGIYFGEPSYVKKTEALDSLKYSSQEIERIVRIAFNLANRRRKKLTSVDKENVLSSSKLWRQIVNDVKKDYPEVEVNHMLVDACSMHLITQPTQFDVIVTENLFGDILSDEASVIPGSLGLSPSASFGQTGTRLYEPIHGSAPDIANEDKANPFGMVLSLALCLRESLNQNDAANELESIVYSFIQSNKTTADLGGQYRTSKIFKLLKEKYL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_NITEC
Sequence: MTNKLTFTRPDDWHLHLRDGKAMQSVLPDTARRFARAMIMPNLKLPVVTTEQAAAYRARILSALPQELVGQFEPLMTLYLTDTTTPEEISRAKASGIVQAVKLYPAGATTHSDAGVTDIDRCKATLAMMEKLDMPLLVHGEVVDPAVDIFDREKIFIDRVLIPLLQRFPGLRVVFEHITTREAVEFVQSISNRIAATITAHHLMLNRNALFTGGLQPHHYCLPVLKREIHRQALVAAATSGHSRFFLGTDSAPHPLKDKESACGCAGIYSAHAAIEFYAEIFEQAGRLDRLEAFASFYGPDFYGLPRNTDQISLSKESWQIPGEVEFGGDRLVPLRAGEQVCWRL
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: U6D_CONCL
Sequence: GDACSLLNGDDCGPGELCCTPSGDHQGTCETSCW
What are the official names of this protein?
Conotoxin Cl6d, Cal6.17b.
What are the subcellular locations of this protein?
Secreted.
Protein: RUFY2_MOUSE
Sequence: MATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKGRKSFLSYNKTIWGPLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRELLSEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLDSQVGVIDFSMYLKNEEEIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENELILMRTRQHLEVTKVDVETELQTYKHSRQGLDEMYNDARRQLRDESQLRQDVENELSVQVGMKHEMELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQRLQGSEDGLKEKNEIIARLEEKTNKITTAMRQLEQRLQQAEKAQKEAEAEDEKYAQECLSQSDSLQRQISQKEQQLVQLETDLKIEKEWRQTLQEDLQKEKDVLSHLRHETQKVISLKKEFLNLQDENQQLKRIYQEQEQALQELGSKLCESKLKIDDIKEANKALQGLVWLKDKDATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPSSPKPVRVCDSCHAMLIQRCSSNMP
What are the official names of this protein?
RUN and FYVE domain-containing protein 2, Leucine zipper FYVE-finger protein, LZ-FYVE.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBT_ASACA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPXILTKKTK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL19_PHEZH
Sequence: MNVIEQLRKEEADRLLAQRKVPEFRPGDTVRVNVRIKEGDRERVQAYEGVCIARAGQGVDENFTVRKISFGEGVERVFPILSPMIESIEVKRRGVVRRAKLYYLRDRRGKSARIAERQMTAASKEEPAEKSEA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ASTC_ECOLI
Sequence: MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNALLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECARVMTVGTHGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTINHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAAACEHFVSRGSS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.  Is involved in the utilization of arginine as a nitrogen source, via the AST pathway, and seems also to play a role in ornithine catabolism (PubMed:9696779).
What are the official names of this protein?
Succinylornithine transaminase, SOAT, Carbon starvation protein C, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: FLIE_RHILO
Sequence: MIVNGIGALNLKPGLGDTATDLIQGGVAPATSGNLGTSFAEAVSQAASKTVNTLQNAEQVSLQALKGDADTRQVVDAVMSAQQALQTAVAIRDKVVSAYLEVSRMGI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: NFI_BACVZ
Sequence: MKIHQIHDFDLNDESDFIRTQQSLIHKINLSPVIHPDSVNTCAGVDLAYWEQDGEPYGVCSIIVIDADTKEVIEKVHSMGKISVPYVSGFLAFRELPLIIEAAEKLEAEPDVFLFDGNGYLHYNHMGVATHAAFFLGKPTIGIAKTYLKIKGCDFEMPENEVGAYTDILIDGEVYGRALRTRRDVKPIFLSCGHNIDLESSYQITMKMINRDSRLPIPVRLADLETHVLRTFYRKNHV
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y885_CHLPN
Sequence: MSTMQNCPHFGVCGGCSFPQSNYSDSLKKKEELLHQLFAPLVPSDMIAPIIPCSPSLRGRNKMEFSFFQTYEGEKSLGFISSTKPKKGIPVTTCLLIHEQTMDILKLTREWWDKHPELMAYFPPKNKGSLCTLTVRTGSPQQNFMVILTTSGTPEYRVNEACIDEWKEILLSSSLNIASIYWEEKVAARGISTYYETKLLYGAPSIQQKLSLPSDGNSASFSLRPRSFFQPQITQAAKIIETAKEFINPEGSETLLDLYCGAGTIGIMLSPYVKNVIGVEIIPDAVASAQENIKANNKEDCVEVYLEDAKAFCKRNENCKAPDVIIIDPPRCGMQSKVLKYILRIGSPKIVYISCNPKTQFQECADLISGGYRIKKMQPIDQFPYSTHLENIILLEREIDL
What are the official names of this protein?
Uncharacterized RNA methyltransferase CPn_0885/CP_0981/CPj0885/CpB0914.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: KAD_AGRRK
Sequence: MRLILLGPPGAGKGTQAQRIVEKHGIPQLSTGDMLRAAVAAGTEVGKRAKAVMDAGKLVSDDIVNAIVSERIDQPDCARGFILDGFPRTLVQADATEAMLKAKGLELSAVIEIKVDDAVLADRISGRYTCANCGAGYHDENLRPKVEGVCDRCGSTHFKRRADDNRETVVERLQVYYKETSPLIGYYYAKGKLQSVDGMADIEHVTANIEAILSKL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTSR_STAAC
Sequence: MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY
What is the function of this protein?
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
What are the official names of this protein?
Transcriptional regulator CtsR.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: CYB_RICPR
Sequence: MNKEIIHKKSNGIIEWIDYRLPIFSFLKHFSYYQTPKNLNYLWNLGSIAGIALVIQIITGVILAMHYTPHVDHAFESVERIMRNVNYGWLLRYTHAVGASMFFAAIYLHIARGLYYGSYKTPRELLWHIGIIIFLIMMATAFMGYVLPWGQMSYWGATVITNLFSAIPLVGEPIVIWLWGGFSVDNPTLNRFFALHYLFPFIIVVLVILHLVALHQHGSNNPKGIDVKSTKDTIPFHPYYTVKDFVGFGVYFIIFAYFIFYAPNYLGHPDNYIPANPLVTPAHIVPEWYFLPFYAILRAVPSKLGGVFLMFGSIVVLFLLPWLDTSKIRSGNYRPIYRIAFWIFMADCLFLGYLGSKPVSEPYITISRFAVCYYFCHFLLVLPLIGKYEKPLPLPKVL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Cytochrome b.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TIG_SHEWM
Sequence: MQVSVETTQGLERRLTISVPAEQIEKAVNDSLKNEAKRARIPGFRPGKVPVSVINKRYGKAIRQDITGEVMQRNFVEAIIAEKLNPAGAPTFVPGESDAENFQFVATFEIYPEVELKGLEDIAVEQPTSDVTDADVDTMIETLRKQHATYEAVERAAADGDKAKINFVGSIDGEEFEGGKAEDFELQLGSGRMIPGFESGVEGHKAGEEFDIEVTFPEDYHAENLKGKVAKFAITLNEVQAANLPEVNDEFATLFGVAEGGLEALKAEISKNMGRELEQALKANVKEQVLNGLLEQNEIELPASLIAGEVEVLRKQAMQRFGDQAANMPELPADLFTEQAERRVKVGLLLGEVIKTNELKAEEERVQGLIASMASAYEDPSEVVEYYNGNQEMMQNMRNVALEEQAVEALLKTAKVTEKAVNFEEFMNKATQQG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PEPT_STAEQ
Sequence: MKKQIIERLTRYVKIDTQSNPDSKTTPSTNKQWDLLNLLEEELQSLGLKTDMDEHGYLFATLESNINYNVPTVGFLAHVDTSPDFNASHVNPQIIEAYNGQPIKLGESQRILDPDVFPELNKVVGHTLMVTDGTSLLGADDKAGVVEIMEGIKYLIDHPDIKHGTIRVGFTPDEEIGRGPHQFDVSRFNADFAYTMDGSQLGELQFESFNAAEVTVTCHGVNVHPGSAKNAMVNAISLGQQFNSLLPSHEVPERTEGYEGFYHLMNFTGNVEKATLQYIIRDHDKEQFELRKKRMMEIRDDINVHYNHFPIKVDVHDQYFNMAEKIEPLKHIIDIPKRVFEALDIVPNTEPIRGGTDGSQLSFMGLPTPNIFTGCGNFHGPFEYASIDVMEKAVHVVVGIAQEVANSHQSYK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.