PharMolix/UniProtQA huggingface dataset:
Protein: RPOC1_AGRST
Sequence: MIDQYKHQQLQIGLVSPQQIKAWANKNLPNGEVVGEVTRPSTFHYKTDKPEKDGLFCERIFGPIKSGICACGNSRPSGAENEDERFCQKCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKGLPSYIANLLDKPLKKLEGLVYGDFSFARPSTKKPTFLRLRGLFEEEISSCNHSISPFFSTPGFATFRNREIATGAGAIREQLADLDLRIIIENSLVEWKELEDEGYSGDEWEDRKRRIRKVFLIRRMQLAKHFIQTNVEPEWMVLCLLPVLPPELRPIVYRSGDKVVTSDINELYKRVIRRNNNLAYLLKRSELAPADLVMCQEKLVQEAVDTLLDSGSRGQPIRDGHNKVYKSLSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHQCGLPLEIAIKLFQLFVIRDLITKRATSNVRIAKRKIWEKEPIVWEILQEVMRGHPVLLNRAPTLHRLGIQAFQPTLVEGRTISLHPLVCKGFNADFDGDQMAVHLPLSLEAQAEARLLMFSHMNLLSPAIGDPICVPTQDMLIGLYVLTIGNHRGIYANRYNSCENYPNQKVNYNNNNSKYTKDKEPHFSSSYDAMGAYRQKLISLDSPLWLRWKLDQRVIGSREVPIEVQYESLGTYHEIYAHYLIVGNRKKEIRSIYIRTTLGHISFYREIEEAIQGFSQAYSYTI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CASPC_MACMU
Sequence: MADKKPSKEDPVNMVKLLTRNVLDGIFDDLMENNVLNTEELRNLGKGLNFMVNNAGNLVDNITEKAQMVGKILKDRLLSHPKQLSLEYQHESEDQESEESSASSSSSTESEEENEESKDEERAASAHSMAVPPTAPLEIQGAQPSGRLKLCPHAHFRELKTKRADEIYPVMEKEGRTRLALIICSKEFHYLLNRNGSELDLLGMQDLLENLGYSVVIEENLTAQEMETALRQFAARPEHQSSDSTFLVFMSHGILNGICGTKHWDQEPDVLHDDTIFEIFNNRNCRSLRDKPKVIIMQACRGSGAGIVWFTTDSGKASADTHGQLLQSSICNDAVTKAHVEKDFIAFKSSTPHNVSWRHEMSGSVFISQIIYYFKEYSWSHHLEEIFRKVQRSFETPNVVTQLPTIERLSMTRYFYLFPGN
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.
What are the official names of this protein?
Caspase-12, CASP-12.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
Protein: PHNX_SALPB
Sequence: MNRIHAVILDWAGTTVDFGSFAPTQIFVEAFRQAFDVEITLAEARVPMGLGKWQHIEALGKLPAVDARWQAKFGRSMSAADIDAIYAAFMPLQIAKVVDFSSPIAGVIDTIAALRAEGIKIGSCSGYPRAVMERLVPAAAEHGYRPDHWVATDDLAAGGRPGPWMALQNVIALGIDAVAHCVKVDDAAPGISEGLNAGMWTVGLAVSGNEFGATWDAYQTMSKEDVAVRREHAASKLYAAGAHYVVDSLADLPEVIAHINARLAQGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: FRI4_SOYBN
Sequence: MLLRTAAASASSLSLFSPNAEPPRSVPARGLVVRAAKGSTNHRALTGVIFEPFEEVKKELDLVPTVPQASLARQKYVDESESAVNEQINVEYNVSYVYHAMFAYFDRDNVALRGLAKFFKESSEEEREHAEKLMEYQNKRGGKVKLQSIVMPLSDFDHADKGDALHAMELALSLEKLTNEKLLNLHSVATKNGDVQLADFVETEYLGEQVEAIKRISEYVAQLRRVGKGHGVWHFDQMLLHEGGDAA
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
What are the official names of this protein?
Ferritin-4, chloroplastic, SFerH-4.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YQ23_CAEEL
Sequence: MRKTEKMKRPHNSSHVKQEERADDSHSNSPASSKSIKQENLLKCELCSTVCSSISQLQSHTLSEHVPEKKPSISTSNSAPSTKRVACQQCEDTFEDFAQFAIHMKSHLSSVTSQLFFCPICPVGTPFRDKKSQLEHLTTQHLQIQVTQHICSICDSAFPSPQAQSVHFAEAHKKYSCTNCDFETENEKTFKEHSKQHSRQLIMYGCALCATSYPSQLHLITHVQMSHDQETFYPPSLPIPTPPSPKSTPKQRVLQCSVCDESVLGEDGLDEHRLRKHCKVRFADKCADCQEPLLNETSFVEHCLRHSKDHAHHCPVCRQSLRSDSQIHAHCAYHMSHQDSTSSTSSSPITNGFSFVCPICGEKLDDGFALIEHTKIHL
What are the official names of this protein?
Putative zinc finger protein C09F5.3.
What are the subcellular locations of this protein?
Nucleus.
Protein: GTE9_ARATH
Sequence: MTERNGGFPGDYCFEAPGGDYDEGSDSPRVSEGSNCSKRKVGETFGVSKMVLPLSGLSSSDRKELIRRLRQELEQIRVFQKNFELSRTVALTSSSASGLTRVKSFGMSRCSTGPGKTVNPISAASKPTPVTTAVMLLMKQCEALLKRLMSHQYGWVFNTPVDVVKLNILDYFNVIEHPMDLGTVKNKLTSGTYSCPSEFAADVRLTFSNAMTYNPPGNDVYVMADTLRKFFEVRWKTLEKKLSGTKVHTEPSNLDAHKEKHIVIPVPMAKKRKTTAVDCENVVDPAKRVMTDEDRLKLGKDLESLTEFPAQLINFLRDHNSNEGGIGDDEIEIDINDLSDHALFQLRDLLDEHLREIQNKKSSVEPCEIELLHGSVPGNSSMQHCDGSELDDEVVDIGENEHPTSSISPVTIEKDLVLGNSNGNSLGSVSGDPKMSSLPRASKGLGTIDLEPMLDGATSASPTRGSSVGGLDQLESASPEKISSVEADCQQDGNSAQNEKQLPPEKSYRAAILKNRFADIILKAREKPLNQNDTRDPEKLQREREELELQKKKEKARLQAEAKAAEEARRKAEAQAAAEAAAEAKRKLELEREAARQALMEMEQSVELNENAKFLEDLELLKTVDTDHLTNTIEEEDGPDVGLRSFSFGGSNPLEQLGLFMKQDEDEEEADPLTSPAPEIDIEEGEID
What are the official names of this protein?
Transcription factor GTE9, BROMODOMAIN AND EXTRATERMINAL DOMAIN PROTEIN 9, AtBET9, Bromodomain-containing protein GTE9, Protein GLOBAL TRANSCRIPTION FACTOR GROUP E9.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMB_AROAE
Sequence: MTFPSHNPPETGHPSAAPDEALPAAEAPVPGDPEARFSSRSIRSFVLRQGRMSVAQQRHLDETLPKVGIPYRVAPLDLDAAFGRAAPKIVEIGFGMGETTAKIAAALPDKDFLTIEVHGPGVGSLCKLIAEGVLDNVRIVQHDAVEVLRDMIPERALAGVHVFFPDPWHKKRHHKRRIIQPDFVALIASRLAPGAYLHCATDWEEYAQWMLEVLAAEPALENTADGYAPRPAYRPLTKFENRGLKLGHGVWDLVFRRRG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RL6_BURP1
Sequence: MSRVGKSPIALQGAEVKLADGAITVKGPLGTITQAVNPLVNVANNDGTLNLSPVDDSREANALSGTMRAIIANAVHGVTKGFERKLTLVGVGYRAQAQGDKLNLSLGFSHPVVHQMPEGIKAETPTQTEIVIKGIDKQKVGQVAAEVRGYRPPEPYKGKGVRYADEVVILKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TTCA_KLEP7
Sequence: MQENQELTKKEKYNIDKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQKSAPISFSLVAVNLDQKQPGFPEHILPAYLEQLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIERFSQAKGFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLSDVNLFDFKGITHGSEVVDGGDLAFDREDIPLQPAGWQPEEEDARLDELRLNVVEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H4_STYPL
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTALDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YCDA_BACSU
Sequence: MFQKKTYAVFLILLLMMFTAACSGSKTSAEKKESETEKSSDIAQVKIKDVSYTLPSKYDKSTSDDQLVLKVNVAVKNTGKDPLNVDSMDFTLYQGDTKMSDTDPEDYSEKLQGSTINADKSVEGNLFFVVDKGKQYELNYTPESYGDKKPKSVTFKIDGKDKKILATADKLQDSAKALSAYVDVLLFGKDNADFEKITGANKNEIVNDFNESAKDGYLSASGLSSTYADSKALDNIVNGIKEGLSKNSSIQAKTTSISKDEAIVEATVKPVDASSLSDRIEDKVKDYYSKNSSASYEEAVKYALQVYPEEFKKLGPASSEKTVEVKMKKNDIDQWQLDMDDYRAAELVEAFIKE
What are the official names of this protein?
Uncharacterized lipoprotein YcdA.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane raft. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: HIS4_CLOB6
Sequence: MIILPAIDLKEGKCVRLYQGDFKASKVVAEDPIEVALKFKENGAEYIHIVDLDGALTGQIKNLSIISSIIKTINIPVELGGGIRNLNTIDMLIDAGIERVILGTAALNNRGLVKEAVKKYDRKIAIGVDAKNEKVAINGWLNVSSTNYIDFAKEMENIGVRNIIFTDISKDGTLKGPNLNQLKKLNESVSCNIIASGGIKDIEDLKVIKEMDIYGAIVGKAIYSGNIDLNEAIKIINKESSR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIP1_HUMAN
Sequence: MMPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPGIQPSCGMIKRFSGLLHGSPKTTSLAASAASTETLTPTPERNEGVYTAIAVQEIQGNPASPAQEYRALYDYTAQNPDELDLSAGDILEVILEGEDGWWTVERNGQRGFVPGSYLEKL
What is the function of this protein?
Involved in regulation of the actin cytoskeleton.  May regulate WAS actin-bundling activity.  Bridges the interaction between ABL1 and PTPN18 leading to ABL1 dephosphorylation.  May play a role as a scaffold protein between PTPN12 and WAS and allow PTPN12 to dephosphorylate WAS.  Has the potential to physically couple CD2 and CD2AP to WAS.  Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymerization required for synapse induction during T-cell activation (By similarity).  Down-regulates CD2-stimulated adhesion through the coupling of PTPN12 to CD2.  Also has a role in innate immunity and the inflammatory response.  Recruited to inflammasomes by MEFV.  Induces formation of pyroptosomes, large supramolecular structures composed of oligomerized PYCARD dimers which form prior to inflammatory apoptosis.  Binding to MEFV allows MEFV to bind to PYCARD and facilitates pyroptosome formation.  Regulates endocytosis and cell migration in neutrophils.
What are the official names of this protein?
Proline-serine-threonine phosphatase-interacting protein 1, PEST phosphatase-interacting protein 1, CD2-binding protein 1, H-PIP.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Cell projection, uropodium. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, lamellipodium. Cleavage furrow. Note=Mainly cytoplasmic in T-cells (PubMed:9857189). Colocalizes in cluster with CD2 near the cell surface membrane in activated T-cells (PubMed:9857189). In monocytes, forms a branched filamentous network in the cytoplasm (PubMed:19584923). In transfected cells, forms relatively straight filaments radiating out from the nucleus (PubMed:19584923). Filament formation requires an intact tubulin cytoskeleton (PubMed:19584923). In migrating neutrophils, colocalizes with PIP5K1C and DNM2 to the trailing edge of the uropod in a actin-dependent manner (PubMed:18480402). Colocalized with PTPN12 in the cytoplasm and the perinuclear region. During interphase, colocalizes with F-actin in the cortical cytoskeleton, lamellipodia, and stress fibers. In dividing cells, colocalizes with the F-actin rich cytokinetic cleavage furrow. Colocalized with CD2AP and WAS in the actin cytoskeleton within the cytoplasm. Colocalized with CD2, CD2AP and WAS at the site of T-cell:APC contact (By similarity).
Protein: MURC_BURM1
Sequence: MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTDRLAALGARIAIGHDAANIEGANAVVVSTAVRSDNPEVLAARAQRVPIVQRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGTGDFIVAEADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCVDDPNVRQIIPFISKPVVRYGLSPDAQVRAEDIDARDGRMHFTVIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVSDDAIQQALAEFNGVGRRFQRYGDVPTADGGRYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAAIATANGDALSRALRAAGKVEPVFVETVDALPEALAKVAQDGDVVITMGAGSIGGVPAKIVQNTQQKG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCRA_STAAC
Sequence: MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVLSSDWNVGDKVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED
What is the function of this protein?
Essential helicase.
What are the official names of this protein?
ATP-dependent DNA helicase PcrA, DNA 3'-5' helicase PcrA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: KITH_FOWPN
Sequence: MSSGSIHVITGPMFSGKTSELVRRIKRFMLSNFKCIIIKHCGDNRYNEDDINKVYTHDLLFMEATASSNLSVLVPTLLNDGVQVIGIDEAQFFLDIVEFSESMANLGKTVIVAALNGDFKRELFGNVYKLLSLAETVSSLTAICVKCYCDASFSKRVTENKEVMDIGGKDKYIAVCRKCFFSN
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
Protein: ASSY_BACC7
Sequence: MEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKALSVGAIKSYMIDVQEEFANEYALMAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGATAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKENDVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTLALEDTPNKPEFVEIGFEAGVPTTLNGTAYPLSELIKTLNAFAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLTLVKEVAHFKPMIEQKITELIYNGLWFSPLKQALHAFLQETQKNVTGMVRVKLFKGHAIVEGRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKVYSQVNQKKVEA
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_STRPC
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTRLEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVEAERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTN6_HUMAN
Sequence: MAEKTQKSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQALIINAYPDNITPDTEDPEPKPMIIGTNNVFEVGCYSQAMKMGDNNVIESKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVIYGADCLRRVQTERPQPQTLQLDFLMKILPNYHHLKKTMKGSSTPVKN
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Dynactin subunit 6, Dynactin subunit p27, Protein WS-3.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore.
Protein: YE98_SCHPO
Sequence: MRVITLSGITLFLLASLASAIELTFKLENQEKQCYYLDSFHTGEKTHFTYAVQSGGSFDVDYMIKAPSQKTVALGKKRRQADVFFTLEEKGEYEFCFDNHMSTFTDKIVTMEITMENELSLPALTRDEAKDYKKDSMQSTVLEISTALSEIDRVQNYFKTREHRNYSTVKSTQARIFWFSLAESIMVVALSALQVFIVKTFFKRSGRRGV
What are the official names of this protein?
Uncharacterized membrane protein C17A5.08.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: KHSE_ECOBW
Sequence: MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPETAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_CAMJE
Sequence: MKELVNILDFLPEELGEKIKPMFRVKQIYQWIYQKYANNFSDMSSLPKDLRLELARNFHFSPVKCVKNEQSKDGSIKYLFELIDGLRVESVLLPMKEEKIDAEGKRISHARYTICVSSQVGCKSGCSFCLTAKGGLKRNLSAGEIVGQILWIKKQNNIPYERRVNIVYMGMGEPLDNLKNVSKAVKILAQNEGLAISPRRQTISTSGLAKQIKELGQMNLGVLLAISLHAVNDELRTELMPINKAYNIAAIMDAVREFPIDQRKRVMFEYLLIDGINDKLEHAKELVKLLNGIKAKVNLILFNPHEGSLYKRPSLENAIKFQDLLSNKGVTCTIRESKGLDISAACGQLKERAKEQ
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASE2_ACRSP
Sequence: AYVSQSGAPWGLGRISHK
What is the function of this protein?
Subtilisin-like serine protease.  Cleaves prothrombin at 151-Ala-|-Met-152, 271-Arg-|-Thr-272 and 316-Tyr-|-Ile-317 to produces meizothrombin(desF1)-like molecules.  Degrades fibinogen.  Inhibits plasma coagulation.
What are the official names of this protein?
Subtilisin-like serine protease AS-E2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: GMHA_ACTSZ
Sequence: MYLDQIKTELLEAQDVLQKFIADENNIKLIQQAALLISDSFKQGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHLSCVSNDFGYDYVFSRYVEAVGKPGDVLFGLSTSGNSKNVLNAIQAAKQKDMKVIAMTGKDGGEMAGLADVEIRVPHFRYADRIQEIHIKVIHILMMLIEFEMAKDV
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED21_AEDAE
Sequence: MADRLTQLQDTVNQQAEHFCNSIGILQQCSVPSKFPGFERTGSQTPQQNQQEDYAQLFSTLISRCAKDIDTLIESLPSEESSIELQVQALKRLEIENQESAEKLEEVVRKGELLLEKIQAALSDIAQSQLDMQYSSSPKKQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, Mediator complex subunit 21.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RFC5_ORYSJ
Sequence: MLWVDKYRPKTLDKVTVHDQVAQNLKKLVAEQDCPHLLFYGPSGSGKKTLVMALIKQMFGAGADKVKMENKTWKIDTGSRNIEIELAMLSSAHHVEMNPSDAGFQDRYVVQEVIKEMAKNRPIDAKGKRAFKVLVLNEVDKLSREAQHSLRRTMEKYSASCRLILCCNSSSKVTEAVRSRCLNVRVNAPSEDQIVQVLEFIGKKENLQLPFGFAARIAAQSNRNLRRAILFFETCKVQQYPFTSNQVAPPLDWEQYVSEIAADIMKEQSPKRLFAVRQKFYELLVNCIPPESILKKLLAELLKKLDSDLKHEICHWAAHYEHKMRLGSKAIFHLEAFVAKFMSIYKEFLVSTFG
What is the function of this protein?
May be involved in DNA replication and thus regulate cell proliferation.
What are the official names of this protein?
Replication factor C subunit 5, OsRFC5, Activator 1 subunit 5.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL16_BORPE
Sequence: MLQPSRRKYRKEQKGRNTGLASRGTHVSFGEFGLKATGRGRLTARQIEAARRAINRHIKRGGRIWIRIFPDKPISQKPAEVRMGNGKGNPEYWVAEIQPGKVLYEMEGVSEELAREAFRLAAAKLPISTTFVARHIGA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: EF105_ARATH
Sequence: MASSHQQQQEQDQSALDLITQHLLTDFPSLDTFASTIHHCTTSTLSQRKPPLATIAVPTTAPVVQENDQRHYRGVRRRPWGKYAAEIRDPNKKGVRVWLGTFDTAMEAARGYDKAAFKLRGSKAILNFPLEAGKHEDLGDNKKTISLKAKRKRQVTEDESQLISRKAVKREEAQVQADACPLTPSSWKGFWDGADSKDMGIFSVPLLSPCPSLGHSQLVVT
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF105.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYT_UREP2
Sequence: MYKFDQKLNHSAAHLLAMALTKFYPNLSLAIGPTIDEGFYYDFNLNDPNTSITPLDLLKIEKEMKKITTQALTFDYEQVTYEKAKELFKHNKYKLDIIEQNKNNSLSIYHSGKWFDLCKGPHVQNTKEIKAIKLLNIAGSYWRGDANNDQLIRIYGVAFSDQDQLDAYLKDLQERKERDHRKIGKDLNLFTFNNLAGQGLPIWLPNGTIIKNQVQKFINEVEFQFNFDTVITPILGSIDLYKTSGHWDHYKDNIFSPVQIDNEILVLRPMTCPHHTLVYSNELRSYRSLPIRLSEHSILHRYESSGGLTGFERVREMILEDCHVFCRFDQIEHEVINAFKMIQEAQEGLGIKTFEIHLSLNDPNDKEKYYDDPQMWEQSQNVLRKMLKDHNIPYKEMVGEAAFYGPKIDFQVKTVLNRIITVSTIQLDFLLPNRFNLTYINESNEQSVPVMIHIGIIGTYERLLAILLEQTKGILPLWLSPIQVVIIPVNENLHTDYVKELNIKLRKHLIRSNVDLRNERLSKKIREAQIQKIPYQIVIGDEEIKNNKMVTYRCYGSEKTTTVSITDFINMLENKIRLKK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.