PharMolix/UniProtQA huggingface dataset:
Protein: SED2_TRIVH
Sequence: MRLLKFVCLLASVAAAKPTPGASHKVIEHLDFVPEGWQMVGAADPAAIIDFWLAIERENPEKLYDTIYDVSTPGRAQYGKHLKREELDDLLRPRVETSESIISWLTNGGVNPQHIRDEGDWVKFSTNVKTAEKLMNTRFNVFKDNLNSVSKIRTLEYSVPVAISAHVQMIQPTTLFGRQKPQNSLILNPLTKDLESMSVEEFAASQCRSLVTTACLRELYGLGDRVTQARDDNRIGVSGFLEEYAQYRDLELFLSRFEPSAKGFNFSEGLIAGGKNTQGGPGSSTEANLDMQYVVGLSHKAKVTYYSTAGRGPLVPDLSQPSQASNNNEPYLEQLRYLVKLPKNQLPSVLTTSYGETEQSLPASYTKATCDLFAQLGTMGVSVIFSSGDTGPGSSCQTNDGKNATRFNPIYPASCPFVTSIGGTVGTGPERAVSFSSGGFSDRFPCPQYQDNAVKGYLKILGNQWSGLFDPNGRAFPDIAAQGSNYAVYDKGRMTGVSGTSASAPAMAAIIAQLNDFRLAKGSPVLGFLNPWIYSKGFSGFTDIVDGGSRGCTGYDIYSGLKAKKVPYASWNATKGWDPVTGFGTPNFQALTKVLP
What is the function of this protein?
Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.
What are the official names of this protein?
Probable tripeptidyl-peptidase SED2, Sedolisin-B.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: OBG_DESAL
Sequence: MKFVDEATLIVQSGDGGRGCVSFRRERFIPRGGPDGGNGGKGGDVVLVATRAKHTLYHFRYKHRFQAQRGGYGSGANRHGKNGEDLLIEVPVGTIVRDAETSEIIADLSVEEERCIVCHGGRGGKGNKHFTSSTYRAPRFAQDGEEGEEKTLKLELKLLADVGLVGLPNAGKSSLITALTAARPKIGAYPFTTLAPSLGVLQDPYGEPVVIADIPGLIEGAAQGAGLGHRFLRHIERNRLLIHLIDASQVTAEDPLASYQAINKELSSYDQALGEKPQIVVLNKMDLPEAEEGACLFKQSCGNLQVLQISAILGEGLDELIEAIFAQLREPGRRPS
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY1B_CANAL
Sequence: MKYSILAILAHLLTNIKATQEVFTLSDLPPDSCPIDSPISCSKNAQELENVNSCCYESPAGVILLTQFWDYNPATGPDNLFTQHGLWGNMCSYGYPQFCDPSLEINPNGEIIRSIIVDQFGDEELYNNMSYSWKDYHGKDSSFWAHEYNKHGTCFSTIKPSCYLSNTPKNQNLYDFFRIAIGLFNKLPTYDWLAEAGIVPTNSKTYSLSEIQSALNDKFGANVFIKCDYNHAINEIWYYHHVKGSLLQHNFLPIDSVAHTNCPSTGIKYPPKGKVAHPTLTTKTTTGTSTTIHNPTGIPARSYVHLSGKSGCLISNGKWYTSGTCATYHFKKTIDDSNIEIRSSKGICGINGNEEFTCSRAVSGGTDFQIKDGKIGYQDKFDWCFGSTTGSGSTAQTSVKLADGSCDSFQLLI
What is the function of this protein?
Rnase which modulates cell survival under stress conditions.  Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death.  Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration (By similarity).
What are the official names of this protein?
Ribonuclease T2-like 1-B, RNase T2-like B.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Vacuole lumen. Cytoplasm. Note=Is released from the vacuole to the cytoplasm during stress conditions like oxidative stress or stationary phase stress.
Protein: SYFB_NATPD
Sequence: MPVVEVDPDELRSLAAIEDKSDDELKDDLFALGLEFEGESDDGDFELEFAPDRLDRLSVEGIARSLRYQYGHDRGIDVPKTNDAEWTITVDESVPEARPYVTGAVVRGLDLDDTQLDSLIQLQEKLHATMGRNRAKGAIGVHDLTMLKGGGARSDGKPSKSITYRGVDPDGDRFVPLDDDAERTPAEVLDAHPTGETYGHLVDGLDRFPAIYDDIGLFSFPPVINGSRTEVDTGTRDLFIELTGTDQWTIDRMLAIICYALSARGGRIESVAVDYGDRTLTRPDLSTTTKTVSHDRIETTLGVDLAGTDVVDLLERSGLDAEADTEGELTYEVEIPAYRVDVLHPADIVDDVGRAFGFNELEPQYPDVSTVGGRHDRSRLEDAVRNTLVGLGFEDLLNFYMTSETELFDRMSLSPDDNAVGAREPPTITEPYSEDYTVVRTWALPSLLMVLENNTHRAYPQDLAEIGLVAGVDESKPTNVAEHRSVAGVVARTDASYEDAKARLQAIGSAFGVDIKTPPTDHPSFIDGRTAAVVIDGEPAGVIGELHPRVLVEHDLEVPVAGFEFRLDALAD
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5772_ARATH
Sequence: MVLENGFPPYPDFLKIFNSHEDSQLLVIPRSYNRYYPNPLPQTAVLKNPEGRFWNVQWTKSQEVIISLQEGWVKFVKDNGLIDRDFLLFTYDGSRSFWVRIHRNGLPLEPTAPIKIQEISDDEDETNGDGDPHMEEEGDTDENMIVSLSLGSSDEVGDDDDDDYDTAICDEVNKASGSSKKGRVTRKHRDDSLASITPQIFLADPNNPFFISTSSCSRRILVIARQVIKDYGLNFDGTVNLIDGFGELTRKVGKWKDRVVIYKWNEMFTRNKVKQGDVIICEIIREEDVVRSIKVHFVKN
What are the official names of this protein?
B3 domain-containing protein At5g57720.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_STRZP
Sequence: MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTGLPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLEKETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHKTIDVSIKQQLKVVKENLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEU3_CORK4
Sequence: MKLAVIPGDGIGTEVTAEALKVMRAALAGSGESIETTDYDLGARRYLRNGELLTDDDLASLREHDAILLGAVGDPRTVPSGVLERGLLLKMRFVLDHHVNLRPSVLYPGVTSPLSDPGKVDFIVVREGTEGLYAGNGGSIRVDTPHEVANETSVNTRYGVERVVRYAFDRAQERRKKLTLVHKTNVLVYAGGLWQRTVDQVAQEYLDVTVDYCHIDAATIYMVTDPSRFDVIVTDNLFGDIITDLAGAVTGGIGLAASGNIDATGTNPSMFEPVHGSAPDIAGKGIADPTAAILSGALLFRHLGKTDEADAIEAAVRNDVASRDGSIRTEEVGTRIANSLDS
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSCA_YERPE
Sequence: MSQISTKHRTVLFRRWMAIICCLIINIAYLVY
What are the official names of this protein?
Yop proteins translocation protein A.
Protein: ISPG_VIBPA
Sequence: MQHESPIIRRKSTRIYVGDVPIGDGAPIAVQSMTNTRTTDVEATVAQIRALEKVGADIVRVSVPTMEAAEAFKLIKQQVSVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVDCARDKNIPIRIGVNGGSLEKDLQMKYGEPTPEALVESAMRHVDHLDRLNFDQFKVSVKASDVFLAVDSYRLLAKKIDQPLHLGITEAGGARAGAVKSAVGLGMLLSEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEAEVSHLGLAGSNKKSAFYEDGKRQKERFDNNDLVNQLEAKIRAKASMMDSENRIEIKVQD
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: FB291_ARATH
Sequence: MISEDLLVEILLRLPVKPLARCLCVCKLWATIIRSRYFINLYQSRSSTRQPYVMFALRDIFTSCRWHFFSSSQPSLVTKATCSANNSSHTPDCVNGLICVEYMSQLWISNPATRKGVLVPQSAPHQKFRKWYMGYDPINYQYKVLFFSKQYLLSPYKLEVFTLEGQGSWKMIEVENIPSPSTRGICIDGVVYYGAQTAHGLRLVRFYVATEKFGDFIEIPVGASNVYDMNFGYSKLVNYQGKLALLAAKSMSMYDLWVLEDAGKQEWSKVSIVLTREMFSYDLVWLGAVGFVAGSDELIVTAHDRFYQIYLVYVDLKMKRSREVWLGGIRCSDRSSLVLTFTDYVESIMLL
What are the official names of this protein?
Putative F-box protein At5g52610.
Protein: YR578_MIMIV
Sequence: MFSKNRNINQFQYAMESQTEFIMYIPDAINSLIHLLDNGSIIPECFKPNLTDINGFVGNLRHLPNKITSIETGLIRQVYFHGDIMIAGSVMYLKDIETLEFICKNIGFRLSLFVEWLYDNKSLHLLESIALSFPSNDVSYLLESVMQYRQNDTTKLIFNMFPSEYNKEIILRNAVITNNLEMLEFAIEKGAILSETDHLIVQSIRTSNLDLIKYIFSHIDLSKLIKLTDTVYYIYANAVYHYSHDVIVFLIESCIDYPDDLLFKLFASNQDCHETIDYIINLKYPDQNELNNILIHICRHSSQSEKYKSVYNSVEKLIELGADFTIDNYQVVIDILKSYFPNVVEIFVKNGLNPNVNPNILKTSIYCCNNFDITKYLIDNGADIHSDPSLIKTAITSGNLKTATFLMDNGAICDESDCEIITKNRHIFDNNFS
What are the official names of this protein?
Putative ankyrin repeat protein R578.
Protein: SYV_STAAE
Sequence: MEMKPKYDPREVEAGRYEEWVKNGYFKPSEDKSKETYTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGITRYDLGREKFLEQAWDWKEEYASFIRAQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVDLYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGEGFIEIATTRPETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIDFGSGAMKVTPAHDPNDFEIGQRHQLENIIVMDENGKMNDKAGKYEGMDRFDCRKQLVKDLKEQDLVIKIEDHVHSVGHSERSGAVVEPYLSTQWFVRMEDLAKRSLDNQKTDDRIDFYPQRFEHTFNQWMENIRDWTISRQLWWGHQIPAWYHKETGEIYVGEEAPTDIENWQQDEDVLDTWFSSALWPFSTLGWPDLESEDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVLLHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWNGARFSLMNIGEDFKVEDIDLSGNLSLADKWILTRLNETIATVTDLSDKYEFGEVGRALYNFIWDDFCDWYIEMSKIPMNSNDEEQKQVTRSVLSYTLDNIMRMLHPFMPFVTEKIWQSLPHEGDTIVKASWPEVRESLIFEESKQTMQQLVEIIKSVRQSRVEVNTPLSKEIPILIQAKDKEIETTLSQNKDYLIKFCNPSTLNISTDVEIPEKAMTSVVIAGKVVLPLEGLIDMDKEISRLEKELAKLQSELDRVDKKLSNENFVSKAPEKVINEEKRKKQDYQEKYDGVKARIEQLKA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4C2_SYNE7
Sequence: MEIGTFPWLTTIILLPIVAALFIPLLPDRDGKGTTIRWYSLIVGLVDFILLVVAFWTSYDFSNPDLQLVESYAWVPQIGLNWSVGADGLSMPLILLTGFISTLAMLAAWPVTFKTRFFYFLMLAMYGGQILVFAVQDLLVFFFAWELELIPVYLLLAIWGGKRRQYAATKFILYTAGSSLFILVASLAMAFSGDVISFDFQTLAAKEYAIGFQLLLYAGFLIAYGVKLPIVPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALFRMNAGMLPEAHARFAPILVLLGVVNILYAALTSFAQRNLKRKIAYSSISHMGFVLIGLGSFTQLGLSGSMLQMVSHGLIGASLFFLVGATYDRTHTLMLDEMGGVGQKMRKMFAMWTTCAMASLALPGMSGFVAELMVFVGFATSDAYGLPFKVVVISLAAIGVILTPIYLLSMLREIFFGPENKTLTEHETLVDAEPREVYIIACLLVPIIGIGLYPKLTTQVYDATLVQLTERLRSAVPVIAQQAEASRDRLSHFPGQAHRQAPPLG
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4 2, NAD(P)H dehydrogenase I, chain 4 2, NDH-1, chain 4 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: HSCB_YERPA
Sequence: MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQTLKHPLKRAEYMLSLQGFDLGNEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSRRVAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQQVEQLEERLFDDFA
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: MRAY_ALKEH
Sequence: MLYHLAMALEGVYSGFNVFQYLTFRTILGVLTALGIALLVGPAVIQRLVEHQIGQQVRDDGPQSHLSKAGTPTMGGALILVAIAVATLLWSDLTNRYVWVVLLTTLAFGVIGGVDDYRKLALGNSKGLSARAKFFWQTVVALMAAVFLFSTAQSPLETSLIVPLFKDVVLPLGLLFIPLVWLVVVGSSNAVNLTDGLDGLAILPSVLVAGGLAVFAYATGHAVFADYLGIPFVAGAGEVVVFCGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGILAVVVRQELVLLIMGGVFVVETLSVMLQVASYKLTGRRIFRMAPLHHHFELKGWPEPRVIVRFWIITVVLVLVGLAMLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU1M_CAEEL
Sequence: MILVLLMVILMMIFIVQSIAFITLYERHLLGSSQNRLGPTKVTFMGLAQALLDGVKLLKKEQMTPLNSSEVSFLLVPGISFVVMYLEWFTLPYFFDFISFEYSVLFFLCLIGFSVYTTLISGIVSKSKYGMIGAIRASSQSISYEIAFSLYVLCIIIHNNVFNFVSKFNLSLLIIYIPFLIMVIAELNRAPFDFSEGERELVRGFNVEFARVAFVLLFLSEYGSLIFFSVLSSAMFFKFSIFMAFSIFSLLIFIRSSYPRYRYDLMMSLFWFKLLPISLIMLCFYAVIFYY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LIPA_RHIL3
Sequence: MVTILDTINPDAKRVRHPEKAHRPDTEVMRKPDWIRVKAPTSKGYAETRAIVKEHKLVTVCEEAGCPNIGECWDKKHATFMIMGEICTRACAFCNVATGKPNALDMAEPENVAKAVKEMGLSHVVITSVDRDDLEDGGAEHFEKVIWAIRAASPMTTIEILTPDFLKKPGALERVVAAKPDVFNHNMETVPGNYLTVRPGARYFHSVRLLQRVKELDPTMFTKSGIMVGLGEERNEVLQLMDDLRTADVDFLTIGQYLQPTRKHHKVESFVTPDEFKSYETVAYSKGFLMVASSPLTRSSHHAGDDFARLRAAREKKLLMAAE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSA_SHEON
Sequence: MSSQSLYKVSGNIAANALVNNDQYKTMYQESIVNPEGFWREHGKRIDWIKPYTKIKKTTFDDHNLSINWFYDGTLNASANCLDRHLAAHSDRVAIIWEGDNANEQRKITYGELHTQVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFSPDSIASRVIDGKSKIVITSDEGMRGGRAIPLKRNIDDALKHPDVTSVEKVIVLKRTGGKIDWVEGRDVWWHSLVETASEHCAVEEMGAEDPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFDYKPGEIYWCTADVGWITGHSYMVYGPLANGATVLIHEGVPNHPSPARLGEMIDRHKVNILYTAPTLIRALMAEGKQHFDKYNGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWWQTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGATEGNLVLLDSWPGQMRTVYGDHERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVSHELVAEAAVVGYPHDIKGQGIYAYVTLTRGTEESEELRQELRQWVRKEIGALATPDLIQWATGLPKTRSGKIMRRFLRKIAANEVTNLGDASTLADPAVIETLIETRLNRNE
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PFA3_EMENI
Sequence: MATLAMSTPSSPTWPKRRPKAWAMRCERYCCAAASYFPLAFVYSLTTWAVYVEASVGLKPSSSSWIGLPSSILGVVLYLALNISYTTAVFTDPGSPLGARSGGGHPYSALPITELPEYTSYTVNSTGGSRFCKKCQCPKPDRAHHCSTCKRCVLKMDHHCPWLATCVGLRNYKAFLLFLIYTSLFCWVDFGVSAIWIWTEVFNDTRYMDGILPVNVVLLSILGGIIGLVLTGFTAWHISLATRGLTTIECLEKTRYVSPLRKALDRHRYDGLLGTNTGGENQDTFGSRLQNYGNQILDAHANAIPGVTRPEEGEESSDNLTPAQQALSRSYADLERQREHDRYEDYLAELDNEKMPHAFDLGWKRNLLHLFGDRPLHWLVPTPTTTGNGWEWEPSRKFLEAQERVRQQREQVAEQQRQHQRDLYLRNMNNSRAWLGNELPPGWTPDQPLSHSDDVARPATGVSMKTLAPRSPRPRPGEEVYAEDLDKDDFVLEPTRGKGSGNQSSREDDWRDWD
What is the function of this protein?
Palmitoyltransferase specific for VAC8.  Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization (By similarity).
What are the official names of this protein?
Palmitoyltransferase pfa3, Protein fatty acyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA3 subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: PTH_STRT2
Sequence: MTKLVVGLGNPGSKYHETRHNVGFMAIDLMAKELGLTFSEEKTFKAEVASTFLNGEKVYFVKPTTFMNLSGLAVRALLAYYNIPMEDFIVIYDDLDMEVGKLRFRQKGSAGGHNGIKSIIAETGTQEFDRIKIGIGRPQKGMTVVNHVLGKFSEDDYAMILLTLDKVETALHHYLKTNDFEDTMRRYNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESSE_STAA8
Sequence: MKDVKRIDYFSYEELTILGGSKLPLVNFELFDPSNFEEAKAALIEKELVTENDKLTDAGFKVATLVREYISAIVNIRINDMYFAPFSYEKDEYILLSRFKNNGFQIRIINKDIAWWSIVQSYPLLMRQEKSNDWDFKQIDDETLENLNNESIDTIGRVLEIEIYNHQGDPQQSLYNIYEQNDLLFIRYPLKDKVLNVHIGVINTFIRELFGFDTDENHINKAEE
What is the function of this protein?
Component of the type VII secretion system (Ess).  Plays a role in Esx protein secretion.  Plays an essential role in the processing and secretion of EssD.
What are the official names of this protein?
Type VII secretion system protein EsaE.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOA_ERWT9
Sequence: MSNRDTLFSTPVANLGDWTFDERVAEVFPDMIQRSVPGYANIISMIGMLAERFVQEDSQVYDLGCSLGAATLSVRRNIKASGCRIIAVDNSPAMVERCRRHIDAFRADTPVEVIEADIRRVPIENASLVVLNFTLQFLRPEERQQLLNTIWQGLKPGGALVLSEKFSFNDADVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKQRLKLAGFQHAELWFQCFNFGSLVALKAGHA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: GCK3_CAEEL
Sequence: MSSSNLAGNTNTTTTSSAASAAAAHSAANASTITSEYSTTQTTTGTFNTDTLSSIGSTSTLHGSQPSQPPPPPPPQVSSPIAAAAAASAALVAQLNPADRWPTEPSAYKLDESIGVGATATVFTAYCLPRNEKVAIKCINLEKCQTSVDELSHEIQAMSQCNHPNVVSYYTSFIAQEELWVVMRLLNCGSMLDILKRKVKAIGKEQAQFGVLDEVSIATVLREVLKGLEYFHLNGQIHRDIKAGNILLADDGTIQIADFGVSGWLASSGGDLSRQKVRHTFVGTPCWMAPEVMEQVQGYDFKADIWSLGILAIELATGTAPYHKYPPMKVLMLTLQNDPPTLETNAERKDQYKAYGKSFKTLIRDCLQKDPAKRPTASELLKYSFFKKGKDKKYLVHTLIENLASVPVVAHHSSKKVASGKLRKDAHGNWEFEYDSPQESDDDSDLEDEEREKKKKKASASASGAGAAGAAGGATGGAASGAPSAQEGGGATTPCPETLNMVLRVRNQQRELNDIKFDYTKSADTVEGIAHELVTAELIDCHDLVIVAANLQKLIDFAESKSDRRSITFALNSGVHANEIPDERTLTGFAQISLLD
What is the function of this protein?
Plays a role in osmotic stress responses by regulating ion homeostasis and by controlling cell volume via the phosphorylation-mediated inhibition of the chloride channel clh-3 (PubMed:15684092, PubMed:17596296).  In addition, increases gpdh-1 translation upon osmotic stress, likely downstream of wnk-1 (PubMed:23076791).  Involved in several developmental processes including the tubular formation of the excretory canals, the formation of the intestine and the progression through larval stages (PubMed:20595048).  In addition, required for germ line development by controlling meiosis and chromosomal segregation during spermatogenesis.  By controlling clh-3 activity, may regulate the development of the excretory canals and fertility (PubMed:18049475).
What are the official names of this protein?
Germinal center kinase 3, STE20-like serine/threonine kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in the nucleus in intestinal cells.
Protein: SIA7E_MOUSE
Sequence: MKTLMRHGLAVCLVLTTMCTSLLLVYSSLGSQKERPPQQQQQQQQQQQQAATATGSTQLVESSPQPRRTAPAGPRQLEGYLGVADHKPLKMHCKDCALVTSSGHLLRSQQGPHIDQTECVIRMNDAPTRGYGLDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQAYNNLQLLSQVLPRLKAFMITRHRMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRIDVYGMVPPDFCRDPKHPSVPYHYYEPSGPDECTMYLSHERGRKGSHHRFITEKRVFKNWARTFNIHFFQPDWKPESPAVNHAEGKPVF
What is the function of this protein?
Predominantly catalyzes the biosynthesis of ganglioside GD1alpha from GM1b in the brain, by transferring the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the GalNAc residue on the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc sequence of GM1b (PubMed:10601645, PubMed:10521438).  GD1alpha is a critical molecule in the communication and interaction between neuronal cells and their supportive cells, particularly in brain tissues, and functions as an adhesion molecule in the process of metastasis (PubMed:9157980).  Also shows activity towards sialyl Lc4Cer (N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine) generating disialyl Lc4Cer, which can lead to the synthesis of disialyl Lewis a (Le(a)), suggested to be a cancer-associated antigen (By similarity).
What are the official names of this protein?
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5, GD1 alpha synthase, GalNAc alpha-2,6-sialyltransferase V, ST6GalNAc V, ST6GalNAcV, Sialyltransferase 7E, SIAT7-E.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: SYN_STAAN
Sequence: MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEIAQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQYVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAPFPRLLNRLYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMGI_MAIZE
Sequence: MGSSGFSWTLPDHPKLPKGKSVAVVVLDGWGEANPDQYNCIHVAQTPVMDSLKNGAPEKWRLVKAHGTAVGLPSDDDMGNSEVGHNALGAGRIFAQGAKLVDQALASGKIYDGDGFNYIKESFESGTLHLIGLLSDGGVHSRLDQLQLLLKGVSERGAKKIRVHILTDGRDVLDGSSIGFVETLENDLLELRAKGVDAQIASGGGRMYVTMDRYENDWDVVKRGWDAQVLGEAPYKFKSALEAVKTLRAQPKANDQYLPPFVIVDDSGNAVGPVLDGDAVVTINFRADRMVMLAKALEYADFDNFDRVRVPKIRYAGMLQYDGELKLPSRYLVSPPEIDRTSGEYLVKNGIRTFACSETVKFGHVTFFWNGNRSGYFDATKEEYVEVPSDSGITFNVAPNMKALEIAEKARDALLSGKFDQVRVNLPNGDMVGHTGDIEATVVACKAADEAVKIILDAVEQVGGIYLVTADHGNAEDMVKRNKSGKPLLDKNDRIQILTSHTLQPVPVAIGGPGLHPGVKFRNDIQTPGLANVAATVMNLHGFEAPADYEQTLIEVADN
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, PGAM-I.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
What are the subcellular locations of this protein?
Cytoplasm.