PharMolix/UniProtQA huggingface dataset:
Protein: FABH_CLOPS
Sequence: MENAKIIGFGLYTPKNLVENERLQEFLETSDEWIRSRTGIERRYISLDENTSDLAVEASKKALNQAGLSAEEIDLIIVATVTPDNFTPSTACIVQDKLGAKNAWAFDINAACTGFIYALKLGRSLIRSGEAKNALIIGAETLSKALNWEDRGSCVLFGDGAGAIVLTSTEEDCGIKCVNVKSDGSKGDSLVIQGLPLNSPFKDGREVSKNYINMNGREIFKFATKVMEESIVEILEKENIKIEDISAIIPHQANLRIIDYVVKRLGIPREKFVTNLQNYGNTSGASIPIALCESINEGNLKKGDNIIMVGFGGGLTWGAALIKL
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_ECOBW
Sequence: MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3037_DESAL
Sequence: MTHIIQESLAGQFLIAMPALNDPNFALSVTYICVHNQDGAFGLVINQSFDSVTGKTLFDQMDMPAVKAAENQTVHIGGPVHQGYVFVLHGRPMEWKASLQISDTVAMSNSTDILQAIASGVGPDPCMIFLGCAGWAPGQLEAELAENSWLTCPGNDDLLFRTPLEERWEKAAQSIGVDLNLLSGVAGHA
What are the official names of this protein?
UPF0301 protein Dalk_3037.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: USTP_ASPFN
Sequence: MANVQSRYNHLFPSPAAAFSGMYTGGLWTNNLGSWPGKANQTVEFSNGTKMTVETTASVMLDRGLDFSSGESLFQTACMPNKKSRPPDPRPSLAVGKPPYSIPLGGPSMYPDPIIHHKKDFVRGYYLHEERLEDVAVLQLPTFRLIGESPVSLARVAVQFLERARKDGKEKLIIDLSNNMGGDINLGFNLFRILFPDKPIYTATRFPSTELIGLMGRVFSTSQGNEAVEHDNTLDLPLVFQNAVTPDHRHSFGSWEKLFGPVEIAGQNMSHLHATYNFTTASTEDNPISGYGGIEFGPSTQLFHAENIIIMTNGICASTCTILARLLKQQGVRSIVFGGRPRAAPMQLLGGSKGGQYWSLVTISHYIKKAREIAVNASGAGSPILSEDELARFLELAPPPLTGFPIRIDSRGGSGVNFRNEYDEKDPTTPLQFVYEAADCRLFWTAENYVFPESSWVAAADAMFGDASCVEESDGHHITP
What is the function of this protein?
Peptidase S41 family protein; part of the gene cluster that mediates the biosynthesis of the secondary metabolite ustiloxin B, an antimitotic tetrapeptide (PubMed:24841822, PubMed:27166860, PubMed:26703898).  First, ustA is processed by the subtilisin-like endoprotease Kex2 that is outside the ustiloxin B gene cluster, at the C-terminal side of Arg-Lys, after transfer to Golgi apparatus through the endoplasmic reticulum (ER) (PubMed:24841822).  Cleavage by KEX2 generates 16 peptides YAIG-I to YAIG-XVI (PubMed:24841822).  To process the precursor peptide further, at least two peptidases are necessary to cleave the N-terminal and C-terminal sides of the Tyr-Ala-Ile-Gly core peptide which serves as backbone for the synthesis of ustiloxin B, through cyclization and modification of the tyrosine with a non-protein coding amino acid, norvaline (PubMed:24841822).  One of the two peptidases must be the serine peptidase ustP; and the other pepdidase is probably ustH (PubMed:24841822).  Macrocyclization of the core peptide derived from ustA requires the tyrosinase ustQ, as well as the homologous oxidases ustYa and ustYb, and leads to the production of the first cyclization product N-desmethylustiloxin F (PubMed:27166860, PubMed:26703898).  For the formation of N-desmethylustiloxin F, three oxidation steps are required, hydroxylation at the benzylic position, hydroxylation at either the aromatic ring of Tyr or beta-position of Ile, and oxidative cyclization (PubMed:27166860).  UstQ may catalyze the oxidation of a phenol moiety, whereas the ustYa and ustYb are most likely responsible for the remaining two-step oxidations (PubMed:27166860).  N-desmethylustiloxin F is then methylated by ustM to yield ustiloxin F which in turn substrate of the cytochrome P450 monooxygenase ustC which catalyzes the formation of S-deoxyustiloxin H (PubMed:27166860).  The flavoprotein monooxygenases ustF1 and ustF2 then participate in the modification of the side chain of S-deoxyustiloxin H, leading to the synthesis of an oxime intermediate, via ustiloxin H (PubMed:27166860).  Finally, carboxylative dehydration performed by the cysteine desulfurase-like protein ustD yields ustiloxin B (PubMed:27166860).
What are the official names of this protein?
Peptidase S41 family protein ustP, Ustiloxin B biosynthesis protein P.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
Protein: MGST2_HUMAN
Sequence: MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGSPEFERVFRAQQNCVEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGYSEAAKKRITGFRLSLGILALLTLLGALGIANSFLDEYLDLNIAKKLRRQF
What is the function of this protein?
Catalyzes several different glutathione-dependent reactions (PubMed:8703034, PubMed:9278457, PubMed:23409838, PubMed:26656251, PubMed:26066610).  Catalyzes the glutathione-dependent reduction of lipid hydroperoxides, such as 5-HPETE (PubMed:9278457, PubMed:23409838).  Has glutathione transferase activity, toward xenobiotic electrophiles, such as 1-chloro-2, 4-dinitrobenzene (CDNB) (PubMed:23409838, PubMed:8703034).  Catalyzes also the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (LTC4) (PubMed:23409838, PubMed:26656251).  Involved in oxidative DNA damage induced by ER stress and anticancer agents by activating LTC4 biosynthetic machinery in nonimmune cells (PubMed:26656251).
What are the official names of this protein?
Microsomal glutathione S-transferase 2, Microsomal GST-2, Glutathione peroxidase MGST2, Leukotriene C4 synthase MGST2, Microsomal glutathione S-transferase II, Microsomal GST-II.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi- pass membrane protein.
Protein: SYI_AERPE
Sequence: MGSVPRVLEGERYDQFALESFVKSYWEENSIYRKVKEKSSRAPRKFYFLDGPPYASAKSIHIGTAWNKVVKDVVLRFYRMTGYNVWDKPGYDTHGLPIEVKIEQSLGVRVKREIEEKVGVENFIAACKRFVDENMEAMTRQFKEIGVFMDWENPYVTYRDEYIESGWWLVKKAWEKGLLYKGYRVLHWCPRCETTLADYEVSEYRELEDPSIYVKFPVEGREGEYLLVWTTTPWTLPANAFVMAHPDMEYVKVRVGRDTLILAKARLDHVMREAGVSEYEVLEVLKGSQLEGLRYRHPLEDVVDAQRELSKWHKVVMAPEAVTPHEGSGLVHSAPGHGTIDYEIAQRIGAPVVSLVDERGFMTEAAGKYSGLYFRGEANKAIVEDLRARGALFHAATIVHRYPVCWRCKTPLLLRATTQWFVAVTRLKNQLMREAEKVEWQPGWAKTRFMNMLRELRDWVISRQRYWGIPLPVWRCSSCGYEHVVGSVEELESMGGRRPENLHRPWVDRVELKCPRCGGSMKRVPDVLDVWFDSGIAFYASLGYPRDRETWERLKPVDFIVEGHDQIRGWFFSLLRSGVIGFGETPYRRVLVHGFALDEQGREMHKSLGNYVDFEELIAKVPRDVVRFWVLQNTVWEDLRFSWKGLDLMRRDFNVIWNVYAFASIYMGLDRFDPRRTSLSSVEDSLEVEDRWILSRLASLKRRYLTAMEDLRIHDAARALRSFIIEDVSHWYLRIIRRRVWEEVDTPSKRAAYATLYKVLWEWLLMAAPLIPYTAEYLYIKVFREAEERPEESIHMLDMPEPEDHLIDSTLEEDMEKARMVLEAILSARNEAGLKLRRPVRRVIIAASNPGVEGSLRRLEGLIRLMANAKEIEFAPASALEATRIYRVEPDYGRLGPKYKRDMPKVLRLIEEKGGEIGRVLAEKGVYEGEYEGLPVKLTLEDVSLKAEYPEWLKVRDTPLGLVAVDTRLTKEEVLEGLARDIVRRIQAMRKEAGYSVEDYVEVWIQGGEDVVEAVNALKEYIKRETRALKLEVGEPPSGVEVLREWELDGEKVVIALKRAAASG
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CR064_HUMAN
Sequence: MVPAPPFLGVLENPVPQWDLSILGSIRIRVSHTEVQGSGSSRSPEALRKESLEVEWTLVLLAIPPRIQPSQQDGGPPKCCDLLRAALLGRHCPLCVPAGEVFSQKRDNEQDRSEFIGQTLKLLVKRNVSLELSCR
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC01387.
Protein: RS17_SYMTH
Sequence: MTAERNLRKTRVGVVTSDKMDKTVVVAVETLVQHPLYKKRVRRTKKFKAHDEHNQCKVGDKVRIMETRPLSKEKRWRVVEIIESAPDYKSAPEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RECA_BACAH
Sequence: MSDRQAALDMALKQIEKQFGKGSIMKLGEQAERKVSTVSSGSLALDVALGVGGYPRGRIIEIYGPESSGKTTVSLHAIAEVQRQGGQAAFIDAEHAMDPVYAQKLGVNIDELLLSQPDTGEQGLEIAEALVRSGAVDIIVIDSVAALVPKAEIEGDMGDSHVGLQARLMSQALRKLSGAINKSKTIAIFINQIREKVGVMFGNPETTPGGRALKFYSTVRLEVRRAEQLKQGNDIVGNKTKVKVVKNKVAPPFRVAEVDIMYGEGISREGEILDMASELDIVQKSGAWYSYNEERLGQGRENSKQFLKENTDLREEIAFFIREHHGISEDSGAEGMEDPNLLD
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUR1_YEAS2
Sequence: MGSNDLINEAYDDSEVVGEERESKSAWMKRWYQLLTSPLDLQLVINEKLEMINWDAYAKSLAKPLGNFLTILFFIIRLLQDNLIKPNYYKLNVKSGAFDLSKSNKLKEFDYLWEISSSFQNSNQFYAFQSWYFVTLRFLNNLFRFTIFILLSLNLYVSCKFMFGYFKTYNLFHLKKEFNSPNLTKHNLKDLSKEYYEDIYKQSLWSMLKHFFRGSRDDGPHVNQNEVEIFFQLRKWIPTNFIINLFVSFSPTAIVFLSFSDVSFTSAIAIVFHQYILDYIITKRFQRSVDDDLILSSAALQEYEDKHIMARINQCSNIDTLSSAMGTRSKTPRIFTTHSLCGEEIREVYNYEKREFEALPKMTESVPGSRETRIKDYGGISQVSDNQSHPIGFHYSPRMSPYYRDKVLDNNLAQSSSNENLEKGGAFLPNQDQNRPSKSLSPLRKTPLSARQKRFEGSEFNVLNKNDINSILRSPKKKKNYHKR
What is the function of this protein?
Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability.  Required for rDNA repeat stability (By similarity).
What are the official names of this protein?
Nuclear rim protein 1.
What is the protein family that this protein belongs to?
Belongs to the NUR1 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein.
Protein: YD2_MDBVW
Sequence: MADNKKSMSRAISEDSNLYNKISGTKRAYSDLHHSNSSIYSAKSFGSSVTIYCAVGNDQQTALVNQNDQFYKNQFMIRASSYPTLVSPVSTENQLSQQLRPHISEAAEVLHQYIAKRSRKN
What are the official names of this protein?
Uncharacterized protein D2.
Protein: FK114_ARATH
Sequence: MNSEVERPSFLSLPDEIILSCLARISRSYYPKLSLVCKTFRTLLISNELIVARLHLKTHETFCHVCLKFPDKPNPSMFTLWIKPGTILTNQLEKNKRSTRDTRLVQIPSSYYYNVPFYLVMVGSEVYGLSQRNDPSSNMFVRNKGDIFLCKAPNMTVARAKASAVVFNGKIYVMGGCMADESVNWGEVFDIKTQTWEALPDPGPEFRFSSIRKIDVFQEKLYVRSNEKKDSVYDPKEEWRVVKGLDMLNRNLGCGTIEIVHYGGKLLILWDKVDLSHDKDIWCAVIALEKRHGSDEVWGNIEWADIVLTVPSSYVFVNSLETGF
What are the official names of this protein?
Putative F-box/kelch-repeat protein At5g28160.
Protein: AQP3_PIG
Sequence: MGRQKELVTRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILVAGQVSGAHLNPAVTFAMCFLAREPWIKLPVYTLAQTLGAFLGAGIIFGLYYDAIWAFANNQLIVSGPNGTAGIFATYPSGHLDMVNGFFDQFIGTASLIVCVLAIVDPNNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTAIAGWGSEVFTTGRHWWWVPIASPLLGSIAGVFVYQLMIGCHLEPPPPSTDEENVKLSQVKHKE
What is the function of this protein?
Water channel required to promote glycerol permeability and water transport across cell membranes.  Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content.  Involved in skin hydration, wound healing, and tumorigenesis.  Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.  Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells.  It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
What are the official names of this protein?
Aquaporin-3, Aquaglyceroporin-3.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: AGRB_LISW6
Sequence: MSNFTVKVPLSERMADVLISKDRWKDDEEGYLKVKYGLEIILINVMKFAIVYGISLATGLLLQTVTVHMSYLWLRRYSFGLHATKTLNCTLISLAMFVLAPFVFQNIPSNNWIVLGTFAFILLNMFLFAPADTESLPLIGEKHRKTLKRKAMIGTLILTGIALLIPFAEMKTLIMVGSLFQVISINPLSYKLLKRRYRNYEKYE
What is the function of this protein?
May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.
What are the official names of this protein?
Putative AgrB-like protein.
What is the protein family that this protein belongs to?
Belongs to the AgrB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GAG_HV1Z2
Sequence: MGARASVLSGGKLDAWEKIRLRPGGKKKYRLKHLVWASRELERFALNPGLLETSDGCKQIIGQLQPAIRTGSEELRSLFNTVATLYCVHERIEVKDTKEALEKMEEEQNKSKNKKAQQAAADAGNNSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIAWMTSNPPIPVGEIYKRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKGWMTETLLVQNANPDCKTILKALGPQATLEEMMTACQGVGGPSHKARVLAEAMSQATNSAAAVMMQRGNFKGPRKTIKCFNCGKEGHIAKNCRAPRRKGCWKCGKEGHQLKDCTERQANFLGKIWPSHKGRPGNFLQSRPEPTAPPAESFGFGEEITPSQKQEQKDKELYPSTALKSLFGNDPLLQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: NUDI_ECOLI
Sequence: MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWAISGGGVEPGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSANREVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: KAE1_ENCCU
Sequence: MIAMGLEGSANKLGVGIMRDDEILANERLTYAPPPGEGFIPVKTAEHHRSRILGLVAVSLEKAGVDLDDVDIFCYTKGPGMGLPLSVVATVARTLSLYCNKPLVPVNHCIAHIEMGRFITKASNPVILYASGGNTQIIAYHNRRYKIFGETLDIAVGNCIDRFARALKLPNFPAPGLSVERYAKLGKNYIELPYVVKGMDVSFSGILSNIKRKIAEDEQVKRDLCYSLQETVFSALVEVTERAMAFSSSKEVLIVGGVGCNLRLQEMMGIMARERGGVCYATDERFCIDNGVMIAYVGMLMAKSGAAFKLGECFVTQRYRTDSVEVTWRDY
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1, tRNA threonylcarbamoyladenosine biosynthesis protein KAE1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNMA1_THEPX
Sequence: MKKNNRVVVGMSGGVDSSVSAYLLKEQGFDVIGVTMQIWQDKDEEAVRVEGGCCSLSAVNDARRVANKIGIKYYVMNFKDVFKEKVIDYFVDEYLRGRTPNPCIACNKYIKFEELLKRAWMIDAYYVATGHYAVKEYDEERGRYLLKKSVDTSKDQTYVLYNLTQTQLEHILFPLGKYKKDEVRELAKNLGLPVASKPDSQEICFVTDNDYGKFIRENAKEEIKPGEFRDTRGRFLGYHKGIIHYTIGQRKGLGISVGKPLYVVDIDAENNVVVLGYGDEVFGDELISYNNNFISIDKLEREMRVKAKIRYNAKEQDAVIRPLEDGKVFVKFDNPQRAITPGQSVVFYDGDIVVGGGTIERKVR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 1.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y738_METTH
Sequence: MRFRVTPYHGNLLGDHERLAAFREAISSRARGLTYDLGAGSGILSFFASEYADRVIAIERDPKIAACAGENLSGLDNVSVVNEDALHYEFSAADTIICEMLDTALIDEEQVPVLRRALKFLRNDGTVIPQAVFNAAEPVTVNFENIMYDENLSQPSSGPMRVYDRVEFRGNLPEIFRGSLKLQASSPFNAIRIISFTLTAPGIICGPTPMMNPPLIIPLEETGDKGEVEIKLSYRMGGGLDSVEASII
What are the official names of this protein?
Uncharacterized protein MTH_738.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1452.
Protein: Y1653_METJA
Sequence: MTTKLYVDFGGYSAIEKGNLIIPRDNILNKEDFDSIEIGEVVDIYSKRGKFLGRGFKNPKEVRIMTLRKEDLDENYIREKIIKANEYRLKLGFKDTYRMVYTQSDWLNGLVIDKYNDIATVQIFNYGIEKMKDVVVETLLDLGIDSIYEKSSGRNRKRAGLPEVEGILAGEKTETIIQEGEAKFKVTFDGQKTGFFLDQRENRLELEKFIKEGDRVLDICCYTGGFSVHAAIRGAEVVGVDLSKKALKLAEENMELNNIPKDRYEFIEGNAFKVMEEFIEDGEKFDVVILDPPAFAQSKKALKSAIKGYHMLNRFGAKLADRLLVTCSCSQPLEPDAFKALVIDACLKAKKWAKIIKYGSQSPDHPITSKGTEYLKCLFLSVEEI
What are the official names of this protein?
Putative ribosomal RNA large subunit methyltransferase MJ1653.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRC1_MOUSE
Sequence: MRLLLLLAFISVIPVSVQLLDARQFLIYNEDHKRCVDALSAISVQTATCNPEAESQKFRWVSDSQIMSVAFKLCLGVPSKTDWASVTLYACDSKSEYQKWECKNDTLFGIKGTELYFNYGNRQEKNIKLYKGSGLWSRWKVYGTTDDLCSRGYEAMYSLLGNANGAVCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDKDKLFGFCPLHFEGSERLWNKDPLTGILYQINSKSALTWHQARASCKQQNADLLSVTEIHEQMYLTGLTSSLSSGLWIGLNSLSVRSGWQWAGGSPFRYLNWLPGSPSSEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNNTLNPFIIPSASDVPTGCPNQWWPYAGHCYRIHREEKKIQKYALQACRKEGGDLASIHSIEEFDFIFSQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLPGEPSHENNRQEDCVVMKGKDGYWADRACEQPLGYICKMVSQSHAVVPEGADKGCRKGWKRHGFYCYLIGSTLSTFTDANHTCTNEKAYLTTVEDRYEQAFLTSLVGLRPEKYFWTGLSDVQNKGTFRWTVDEQVQFTHWNADMPGRKAGCVAMKTGVAGGLWDVLSCEEKAKFVCKHWAEGVTRPPEPTTTPEPKCPENWGTTSKTSMCFKLYAKGKHEKKTWFESRDFCKAIGGELASIKSKDEQQVIWRLITSSGSYHELFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPGMSWNDINCEHLNNWICQIQKGKTLLPEPTPAPQDNPPVTADGWVIYKDYQYYFSKEKETMDNARAFCKKNFGDLATIKSESEKKFLWKYINKNGGQSPYFIGMLISMDKKFIWMDGSKVDFVAWATGEPNFANDDENCVTMYTNSGFWNDINCGYPNNFICQRHNSSINATAMPTTPTTPGGCKEGWHLYKNKCFKIFGFANEEKKSWQDARQACKGLKGNLVSIENAQEQAFVTYHMRDSTFNAWTGLNDINAEHMFLWTAGQGVHYTNWGKGYPGGRRSSLSYEDADCVVVIGGNSREAGTWMDDTCDSKQGYICQTQTDPSLPVSPTTTPKDGFVTYGKSSYSLMKLKLPWHEAETYCKDHTSLLASILDPYSNAFAWMKMHPFNVPIWIALNSNLTNNEYTWTDRWRVRYTNWGADEPKLKSACVYMDVDGYWRTSYCNESFYFLCKKSDEIPATEPPQLPGKCPESEQTAWIPFYGHCYYFESSFTRSWGQASLECLRMGASLVSIETAAESSFLSYRVEPLKSKTNFWIGMFRNVEGKWLWLNDNPVSFVNWKTGDPSGERNDCVVLASSSGLWNNIHCSSYKGFICKMPKIIDPVTTHSSITTKADQRKMDPQPKGSSKAAGVVTVVLLIVIGAGVAAYFFYKKRHALHIPQEATFENTLYFNSNLSPGTSDTKDLMGNIEQNEHAII
What is the function of this protein?
Mediates the endocytosis of glycoproteins by macrophages.  Binds both sulfated and non-sulfated polysaccharide chains.  Acts as phagocytic receptor for bacteria, fungi and other pathogens.
What are the official names of this protein?
Macrophage mannose receptor 1, MMR.
What are the subcellular locations of this protein?
Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single- pass type I membrane protein.
Protein: YHY5_SCHPO
Sequence: MNDDSSSSSSGDSSDGSSGTTIVQTNSYPWSAYGRWVVVIICIAALIFFFFIIGIINRRRTKKGQATIPFTNFYPLTAPPPYTAEPEARYNSTIHNPMPPMSQAYRPPPTEPPTVPAYETSSEFPPPAYPEAAATSDAAFRKYDGYAKLG
What are the official names of this protein?
Uncharacterized protein C19C7.05.
Protein: ACPS_STRTD
Sequence: MIFGHGIDLQEISAVKKAYDRNPRFAKKVLTPKEWERFESLSGERQMSFLAGRWAGKEAFSKAWGTGIGAVGFKDIEILNNDKGAPVVTQSPFEGNVFISISHSGDFVQASVILEKNKR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TENSH_CAEEL
Sequence: MAAAALCCASRKSNKYNNEAGYEVYTISEDQLRLKQKMKDRKEGVQVEYITSRLIVLSCTSETSERKFVESLLKASQQIQNAHNKHIRVWNVSQRRHDISSSLDAIPFGWPSETAPSLEKLCTICKNLDQWMLEHPLNIAVIFCKGGLERCAIVVNAFMRFNAISATDDSVDDRFSMQRFSERFLGPDGPPSYKRYLGYFSSLLSGRISVNSDPLYLHNIILTFFEPINVFLKIYERLVPVYQSKTVALNKSSKFEMDGSLKLRGDIFFKCIVAASSPGSSTRCLFTCQLNTCALELHPINSEGYSVVRLHKEELDLIFNDKKIDNRVTVELVVSHTSGPTTIATAAVQSVHSLLPRNNSYETFELAQDDETNRSRLEVEYSEIRKKSTKSSKSANPINNNQEEEMPVGPPVPPKPSTPIMNGERLGEYGVGGHIGNGDVVPERRGILPASLREKINQKKELEGRATPSIEPDLVGRDRYDKASRCFSYVPAKSMQEAFERPRRTSFSRAIEKRENSVENVSQEEVARTEIPQSYQQNDISTPAKWDEQVEDAKQSALLEELARAPSAMQHNYWGNGEVDNVQVVDQAQRAVITPTSTLQRRPKPPARSGSYRTLNDDAYCSDMDELCDPEYYLNYNSNTAPLPPPRRQEQHAGTRSVQLPRKKMNFDAVTDPLDDVLESTKRLGSAYSVGDVRGGQQQQQEQHNASNDFNFSNTLNNTPTDYRQHYRNRNCQSVTTPRNHHFSTPSREQEADAADTWLSGKLKKVRSKRDIDPDIVRRRTQEKMLLEELKDSAANNDENQHNLPNGHARGAGLQNIDPLAEFRREEERLRNTRSPYGEERWRGRMRGKPPTPPPRESSASPVNSLPRGTPAHHMDRQRHNQSVPLPMHHRQFDEDFDVNSLFNFSHDPRQQSTTLERGGRSLSRGARIQDAYYASQQDLSANNRFNSGQERVAAAIYRAETAHRDMYASGTINRAETPGRYFPENSAVLERSSTPSFPVSRATPLPFHPLLYNNGERGGSGHAAGGGGGGHNGYSTMNNRSASPRLFGGSSTLSRRSSVNSVDTSEIIHHHPLFVKDTSKYWYKPTISREQAINMLRDKPPGTFVVRDSNSFPGAFGLALKVSTPPPGVNPGDGSELVRHFLIEPSPKGVKLKGCNNEPVFGSLSALVYQHSITALALPTKLVLPDFDPAATPEHLSATQALLEQGAACNVVYVGSVDVESLTGNECVKRSIATCSQRAINGDSRAVSVHFKVSSQGVTLTDNTRKVFFRRHFNVQSVIFAGMDPIERRFENTRALGFHDGCIAQARLFAFVARIPSSSENACHVFAELEPEQPGSAVVNFINKVMLAQKNRS
What is the function of this protein?
Not involved in axon regeneration after injury.
What are the official names of this protein?
Tensin homolog, C1 domain-containing phosphatase and tensin homolog, Suppressor of vhp-1 deletion lethality protein svh-6.
What is the protein family that this protein belongs to?
Belongs to the PTEN phosphatase protein family.
What are the subcellular locations of this protein?
Cell projection, axon. Note=Localizes to punctate structures along the axon in motor neurons.