PharMolix/UniProtQA huggingface dataset:
Protein: DPO3_LACPL
Sequence: MSLNQQEMFEKLLEQIEMPTGPEFTEAAIDKLTVHQASKVWEFHLHFQHVLPYTQFMTFQNKLQIAFKEIARVTFTIVTDDTEVNGRELAEYWEWIVQHSGIKSPLVQSLCNSNVPTYEDGRVILLAENEVIQNFLTNQALGPIESTYHRLGFPKFSVHTMIDESASQAKIKEFHEQKAKSDQALAQKAEAAIKKANEKRQKQADAPAPIDGPVQLGKQINPQEPAKQMVQITEEERSVVVEGYVFDMEVRTLRSQRQLLILKVTDYSSSMVVKKFSRNADDEAQFAALKPGMWVRVRGSVQEDSFMRDLTINAYDINETSHASRQDTAPADEKRVELHLHSNMSQMDATNSVSDYVKQAAKWGHPAIAITDHSGAQAFPEAFAAGEKNNIKILYGVEANMVDDGVPIAYNDAHVDLKESTYVIFDTETTGLSAIYDRVIELSAVKMVKGNVVDQFEEFIDPGFHLSETTTNLTSITDDMVRGSKSEEEVFKLFREFYGDAIVVGHNVTFDIGFMNTGYARHHMGPITNPIIDTLTLARWLYPNLRGYRLNTLAKKFNVNLEHHHRAIYDAETTGHLNHLFLKDAEDRYQVQFHDQLNDHMNENAAYRHARPFHATLYAQTQAGLKNLFRIISLSNVEYYYRVPRVPRSVLNKYRDGILVGSACSSGEVFTAMMQKGKEEARQKAGYYDFLEVQPKPAYSALIESGLIADTDHLEEIISNMVELGHEMNIPVAATGDVHYLNPEDKIYRKILIHSQPGNPLNRTERPDVHFRSTDEMLKDFDFLGTETAHEVVVDTPRALADQFEIVRPVKDKLYTPRMKGAEAEIEKLTMDRAHAWYGNPLPEIVQKRVDKELKSIIGNGFSVIYLIAQRLVFKSNKDGYLVGSRGSVGSSIVATLSGITEVNPMPPHYRCPNCQYSHFYTNNEYGSGYDLPPKDCPECGTDMVRDGQNIPFETFLGFYGNKVPDIDLNFSGDYQPIAHNYTKVLFGEKNVYRAGTIGTVADKTGYGYVKAYERDTNQTLRSAEVDRLAKGTTGVKRTTGQHPAGIIVVPDYMDIYDFTPVQYPADDQSAAWQTTHFDFHSIHDNILKIDILGHDDPTMIRMLQDLSGVQPESIPPVDPHVMKIFSSPEVLGVTEDQIFSKTGTLGIPEFGTRFVRGMLEETHPSTFNELLQISGLSHGTDVWLGNAEELIKDGTVTLAEVIGCRDNIMTDLIHYGMESDMSFQIMEHVRKGRGIPDEWQQAMKDANVPDWYIESCLKIKYMFPRAHAAAYILMALRVAYFKVYFPLIYYTAYFSVRADDFDLVAMAHGKDAVKASMKAITDKGMDASAKEKNLLTVLELANEMLERGFKFSMVDLDKSDASDWLIDGDTLIAPFRAVPGLGLNVAKQIVAARADKPFLSKEDLSKRGKVSKSLIDFMTENGVLSDLPDENQLSLF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CERS2_MOUSE
Sequence: MLQTLYDYFWWERLWLPVNLTWADLEDKDGRVYAKASDLYITLPLALLFLVIRYFFELYVATPLAALLNVKEKTRLRAPPNATLEHFYQTSGKQPKQVEVDLLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTYYLIAFVAGMAVTVDKPWFYDLRKVWEGYPIQSIIPSQYWYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILLCFSWFANYVRAGTLIMALHDASDYLLESAKMFNYAGWKNTCNNLFIVFAIVFIITRLVIMPFWILHCTMIYPLELYPAFFGYYFFNFMMAVLQMLHIFWAYFILRMAHKFITGKLIEDERSDREETESSEGEETAAGAGAKSRLLANGHPILNNNHPKND
What is the function of this protein?
Ceramide synthase that catalyzes the transfer of the acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward very-long-chain fatty acyl-CoA (chain length C22-C27) (PubMed:15823095, PubMed:18165233, PubMed:20110363, PubMed:23275342).  N-acylates sphinganine and sphingosine bases to form dihydroceramides and ceramides in de novo synthesis and salvage pathways, respectively (PubMed:15823095, PubMed:18165233, PubMed:20110363, PubMed:23275342).  Plays a non-redundant role in the synthesis of ceramides with very-long-chain fatty acids in kidney, liver and brain.  Regulates the abundance of myelin-specific sphingolipids galactosylceramide and sulfatide that affects myelin sheath architecture and motor neuron functions (PubMed:19801672, PubMed:32279995).
What are the official names of this protein?
Ceramide synthase 2, CerS2, LAG1 longevity assurance homolog 2, Sphingosine N-acyltransferase CERS2, Translocating chain-associating membrane protein homolog 3, TRAM homolog 3, Tumor metastasis-suppressor gene 1 protein, Very-long-chain ceramide synthase CERS2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RBFA_STAA8
Sequence: MSSMRAERVGEQMKKELMDIINNKVKDPRVGFITITDVVLTNDLSQAKVFLTVLGNDKEVENTFKALDKAKGFIKSELGSRMRLRIMPELMYEYDQSIEYGNKIERMIQDLHKQDR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNTB_HAEIN
Sequence: MSEGLVQAAYILAALLFIMSLAGLSKHETAKAGCWFGIVGMTIALIATIFGPHSEGTFWIIIAMIIGGAIGVQRALKVEMTEMPELVAILHSFVGLAAVLVGFNSYGLHHEALMPEGLDAAAQAAFVAEQAVLTNIHNVEVFLGIFIGAVTFTGSVVAFGKLSGKINSKALMLPHRHKLNLAALVVSALLMVAFLNNPESIFPVLLMTAIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFILNNDLLIVTGALVGSSGAILSYIMCKAMNRSFVSVIAGGFGNDVQVSSSEEQGEHRETTAEEVAELLKNASSVIITPGYGMAVAQAQYPVADITAKLRERGVNVRFGIHPVAGRLPGHMNVLLAEAKVPYDVVLEMDEINDDFADTDVVLVIGANDTVNPAAMEDPNSPIAGMPVLEVWKAQNVIVFKRSMAVGYAGVQNPLFFKENTQMLFGDAKDRVEDILKAL
What is the function of this protein?
The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.
What are the official names of this protein?
NAD(P) transhydrogenase subunit beta, Nicotinamide nucleotide transhydrogenase subunit beta, Pyridine nucleotide transhydrogenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the PNT beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STEB_SALTY
Sequence: MPISICKHGAPFVVQHENRYGSGASQSSSLSKSIRHISNSHEEIKFISCYSANGACFSNAQMLANASGRPVIGYYGKINKLTASLDNSGRIFRPQHKLAANICYVGNRLLSAPVQLGFGLKHLLTCHSNGNVR
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.
What are the official names of this protein?
Secreted effector protein SteB, Salmonella translocated effector B.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion systems 1 and 2 (SPI-1 and SPI-2 TTSS), and delivered into the host cytoplasm.
Protein: DTD_ALIFM
Sequence: MIALIQRVSEAAVKVDGEVTGEINQGLLILLGVEREDDEAKAKRLMERVLTYRVFEDQDGKMNLNVQQVNGSVLVVSQFTLPADTKKGTRPGFSKGAHPVDAERLYDYFSDLCEEKLHTQRGRFAADMKVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAMK_MAGGM
Sequence: MWIDLLARERSDKMSEGEGQAKNRLFLGIDLGTSHTAVMTSRGKKFLLKSVVGYPKDVIGLKLLGRPYVVGDEAFEMRSYLDLRYPLQDGVLSEISDRDIEVARHLLTHVVKSAEPGANDEICAVIGVPARASGANKALLLKMAQEVVHTALVVSEPFMVGYGLDKLNNTIIVDIGAGTTDICALKGTVPGPEDQVTLTKAGNYLDERLQNAILERHPELQMNTNVACAVKEQFSFVGARGEAATFEFRAAGKPVRCDVTESVKIACEALMPDIIESIEILLRSFQPEYQATVLQNIVFAGGGSRIRGLAAYVKDKLRPFGNADVTCVKDPTFDGCRGALRLAEELPPQYWCQLGDVSGQ
What is the function of this protein?
Protein with ATPase activity which forms dynamic cytoplasmic filaments that are involved in sorting, concatenating and/or correctly positioning of magnetosomes in the cell.  Not absolutely necessary for assembly of short chains (PubMed:20487281, PubMed:22586444, PubMed:27733152).  Filaments grow from the both cell poles towards midcell, and are probably disassembled at the other end of the cell, a process known as treadmilling (PubMed:27733152).  Polymerizes in the presence of ATP, GTP or a non-hydrolyzable ATP analog (PubMed:22586444).  Required for correct segregation and positioning of magnetosomes following cell division (PubMed:22026731, PubMed:27733152).
What are the official names of this protein?
Actin-like protein MamK, Magnetosome cytoskeleton protein MamK.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family. MamK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Tagged protein forms straight lines extending along most of the cell associated with its inner curvature, in the correct position to be filaments that are seen associated with magnetosomes (PubMed:17601786, PubMed:20487281). The exact pattern depends on the N- or C-terminal location of the tag and the length of the linker to the rest of the protein (PubMed:20487281). Individual filaments are 3-6 nm in diameter and 0.5-1 nm in length and occasionally form bundles. Filaments are in close proximity to magnetosome membranes. Most are near midcell, however some extend to nearly the cell pole; they are not seen in a deletion mutant (PubMed:20487281). Filaments do not colocalize with FtsZ-like (also called FtsZm) foci (PubMed:24272781).
Protein: ASSY_XENTR
Sequence: MSQSKGMVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQNEDFEAARKKAVNLGAKKVYIEDMRQQFVEEYIWPAVQANAIYEDRYLLGTSLARPCIAKKQVEIAKKEAAEYVSHGATGKGNDQIRFELTCYALYPEVKIIAPWRMPEFYNRFRGRSDLMEYAKKHNIPVPVTPKDPWSMDENIMHISYEGGILENPKNHAPPGLYLKTKNPATSPNEPDILEIEFKKGVPVKVTNTKEKTQHSSALGLFCYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYQAHLDVEAFTMDREVRKIKQHLSQRFAEQIYNGFWYSPECEFVRSCITKSQEMVEGKVLVSVLKGQVYVLGREAPHSLYNEELVSMDVQGDYDPADACGFIRINALRLKEFHRLQKSKKN
What is the function of this protein?
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals.  Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SUCC_PELUB
Sequence: MNIHEHQAKQILKKYGAVVPEGVFAFTVDELIEKAKSLKTEKFVLKAQIHAGGRGKAGGVKILNTIDELSVAAKELLGKTLVTHQTGPAGREVKRLYVEESSNIDKEFYLSCLVDRASSKIVFISSDQGGMDIEEVAEKTPEKIITTKIDITDEISDADCEKIIAIYALADDAKKQAIALIKSVYKMFLGTDANMVEVNPLILTKEKKIICLDAKVNFDSNALFRHPEIIELRDLNEEDPTEIDASKHDLAYIKLDGSIGCMVNGAGLAMATMDIIKLYGEEPANFLDVGGGASKEKVSAALKIILSDKNVKGILINIFGGIMRCDVLAQGVVDAAKEINISVPLVVRLAGTNFKEGKEILDNSGLKLISAENLDDAAQKIVEAIK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: CC200_HUMAN
Sequence: MGSAYHWEARRRQMALDRRRWLMAQQQQELQQKEQELKNHQEEEQQSEEKLQPHKKLNVPQPPVAKLWTSQEQPQPSQQQPSVQPPSQPPPQPSTLPQAQVWPGPQPPQPQPPPQPTQPSAQARCTQHTSKCNLQDSQRPGLMNPCQSSPIRNTGYSQLKSTNYIQQW
What are the official names of this protein?
Coiled-coil domain-containing protein 200.
Protein: HP1_DROME
Sequence: MGKKIDNPESSAKVSDAEEEEEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEEKSAASKKDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDAEQDTIPVSGSTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQAEMVPSSVANEKIPRMVIHFYEERLSWYSDNED
What is the function of this protein?
Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation.  Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.
What are the official names of this protein?
Heterochromatin protein 1, HP1, Non-histone chromosomal protein C1A9 antigen.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Chromosome. Note=Colocalizes with Arp6 on centric heterochromatin.
Protein: RL25_PSEU2
Sequence: MNEFTLNAEQRSDLGKGASRRLRRLASLVPAVVYGGDKAPESISMLAKEVAKLLENDAAYSHIIELNVGGKKQNVIIKALQRHPAKGHVMHADFVRVIAGQKLTAIVPIHFLNEEAPVKKGGEISHTTTELEVTCLPKDLPEFIEVDLGSLEVGDNVHLSELKAPKGVEFVALAHGTDLAIANVHAPRIVKDEEEGEAEEGAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: LIPM_HALH5
Sequence: METWRFIDSGDRDPAYNMALDEALLNWHSEGLIPPTIRFYGWNPPTLSIGYFQKVQKEINMEMVEKHQLGFVRRPTGGRGVLHDKELTYSVIVTEEHPDMPASVTEAYRIISQGILEGFRDLGLDAYFAVPKTEEEKNALKNPRSAVCFDAPSWYELVVEGRKVAGSAQTRQKGVILQHGSIVLDIDEDKLFDLFNYPSERVRERMQRNFKNKAVPINELRDVPLSMEEVKKAFKDGFEKGLSIKLEPYTLTDAEEAEVKQIAKERYETDEWNFRK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
What are the official names of this protein?
Octanoyltransferase LipM, Octanoyl-[acyl-carrier-protein]:[GcvH] N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipM family.
Protein: POB3_ASPFU
Sequence: MRTAEAFDNIYLDLSKQPGKCKLAESGLGWRPSGGGETFTLDSNNIGAAQWSRAAKGYELKILSRSSGVIQLDGFDQEDFERLSKAFKIWYGINVENREHALRGWNWGKAEFTKAELAFNVQNRPAFEIPYSEISNTNLAGKNEVAVEFALTSDGDANAQPSGSTKNRGRKAAAGPDELVEMRFYIPGTAVKTEKGIKTENDENGEEEEEGEEQNAANLFYETLMEKAEIGDVAGDTFATFLDVLHLTPRGRFDIDMYESSFRLRGKTYDYKIQYASIKKFFLLPKNDEMHTLIVLGLDPPLRQGQTRYPFLVMQLKLDEEISLELNMTEELLESRYKDKLEPRYEEPIHQVVTKIFRGLSGKKVIMPSKDFVSHHGHSGVKCSIKANEGLLYFLDKSLIFVPKPATYVQIENIAVITMSRVGGAVSASRTFDITVTLKAGMGEHQFSNINREEQQPLEEFFKAKNIRFKNEMSDDTSALIAAALDNDDMMSSDEDGGRADRGSADEDEESVDEDFQAESESDVAEEFDSEHESSGSASDAEMDDASDAGDDEEDVDMSEEEERPKKKSKIGK
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
What are the official names of this protein?
FACT complex subunit pob3, Facilitates chromatin transcription complex subunit pob3.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Protein: COBT_DESPS
Sequence: MSLLDRTLLEIFPQDSDSRDAAKARLDNLVMPHWALGDLMDLAIDLAGMQRTIKPLVDKRAIVTMAGDHGVAAEGVSKFPAEVTVQMVHAIIGGSAGVNALARSAGADVFVVDMGVNADLRDLVEQKKLINKKVGLGTGNIAKGPAMSRAMAVRAVEGGIDVAFALSTKYNIIGTGEMGIGNTTPSAAIAAVCTGKTVEEITGRGSGLNDAELQTKIDIIKKSIEINKPNSKDGLDILAKVGGFEIGGIAGLIIGCAAKKIPVVVDGYISTAGALIAAKIEPFVRDYLIFAHRSVEPGHVHMQEFLGCKRPLLDLNFRLGEGTGAAMAMNLVDGAKAILTDMSTFDEIAVTAPEK
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: KAB10_OLDAF
Sequence: GLPTCGETCFGGTCNTPGCSCSSWPICTRD
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Kalata-B10.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: REV_OMVVS
Sequence: MASSKNMPSRITQKSMEPPLRETWQQVVQEMVMRKQRDEEEKQNLVTGLQASSGDPIYTGNSSDRSTRGPGGKTKRRKGWFQWLRKLRAREKNIPSQFYPDMEGNCAGLENLTLGEGMEENPIYDSTAATNTANMDGRNWMEWR
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rev.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: RIMP_BURMA
Sequence: MQLTELIETTVTGLGYELVDLERTGRGMVCVYIDQPAGITIDDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFTRFAGSEAVITLKKPLDGRKTYRGILHAPNGETIGLEFERKKGEAAMLDFTLADIDKARLIPHVDFRSRKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_GLAP5
Sequence: MTPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVVAKKEVNEGQDFFPLTVDYQERTYAAGRIPGGFFKREGRPSEGETLIARLIDRPVRPLFPEGFFNEIQVIATVVSVNPQISPDLVAMIGASAALSLSGVPFNGPIGAARVGFIDNQFVLNPTTSEQRLSRLDLVVAGTDKAVLMVESEADILTEEQMLAAVVFGHEQQQVVIENIKEFVKEAGKPRWDWVAPEPNTDLINKVKALAEARLGDAYRITEKQARYEQIDAIKADVIAQLTAEDETISSGKIVDIITALESQIVRSRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSALFTRGETQALAVATLGTERDAQIIDELTGEKSDRFLFHYNFPPYSVGETGRIGSPKRREIGHGRLAKRGVLAVMPTAEEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDIKIEGITPEIMRIALNQAKGARMHILGVMEQAIPAPRSEISDFAPRIHTMKIDPKKIKDVIGKGGATIRALTEETGTSIDIDDDGTVKIAATDNNAAKRVMERIEEIVAEVEVNAIYKGKVTRVVDFGAFVSILGGKEGLVHISQITDARVERVADYLSVGQDVQVKVVEIERQGRIRLTMKDLNGDATAREVVEEIQELAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX6_DROME
Sequence: MRNLPCLGTAGGSGLGGIAGKPSPTMEAVEASTASHRHSTSSYFATTYYHLTDDECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGSGYEVLSAYALPPPPMASSSAADSSFSAASSASANVTPHHTIAQESCPSPCSSASHFGVAHSSGFSSDPISPAVSSYAHMSYNYASSANTMTPSSASGTSAHVAPGKQQFFASCFYSPWV
What is the function of this protein?
Involved in eye morphogenesis.
What are the official names of this protein?
Paired box protein Pax-6, Protein eyeless.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CS025_XENTR
Sequence: MTSRAKKRIVLPTRPEPPSIEQILQDVHGAIASDPVFICDFSDDSSLSNNATLCEKEKQYWQSCNYVDMNNKLKEALIQLKAKCDVLRSAGEKLEEDIENLREATM
What are the official names of this protein?
UPF0449 protein C19orf25 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0449 family.
Protein: OTUD3_HUMAN
Sequence: MSRKQAAKSRPGSGSRKAEAERKRDERAARRALAKERRNRPESGGGGGCEEEFVSFANQLQALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPFEKHVASLAKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGTEKSSVRELHIAYRYGEHYDSVRRINDNSEAPAHLQTDFQMLHQDESNKREKIKTKGMDSEDDLRDEVEDAVQKVCNATGCSDFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNNRSEAEANTQVTLVKTFAALNI
What is the function of this protein?
Deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys-11'-linked polyubiquitin.  Also hydrolyzes heterotypic (mixed and branched) and homotypic chains (PubMed:23827681, PubMed:35675826).  Important regulator of energy metabolism.  Glucose and fatty acids trigger its nuclear translocation by CBP-dependent acetylation.  In the nucleus, deubiquitinates and stabilizes the nuclear receptor PPARD regulating the expression of various genes involved in glucose and lipid metabolism and oxidative phosphorylation (PubMed:35675826).
What are the official names of this protein?
OTU domain-containing protein 3.
Protein: ACYLT_MYCTO
Sequence: MIAGLKGLKLPKDPRSSVTRTATDWAYAAGWMAVRALPEFAVRNAFDTGARYFARHGGPEQLRKNLARVLGVPPAAVPDPLMCASLESYGRYWREVFRLPTMNHRKLARQLDRVIGGLDHLDAALAAGLGAVLALPHSGNWDMAGMWLVQRHGTFTTVAERLKPESLYQRFIDYRESLGFEVLPLSGGERPPFEVLCERLRNNRVVCLMAERDLTRTGVEVDFFGEPTRMPVGPAKLAVETGAALLPTHCWFEGRGWGFQVYPALDCTSGDVAAITQALADRFAQNIAAHPADWHMLQPQWLADLSESRRAQLRSR
What is the function of this protein?
Catalyzes the transfer of a palmitoyl moiety from palmitoyl-CoA to the 6-position of the mannose ring linked to the 2-position of myo-inositol in phosphatidyl-myo-inositol monomannoside (PIM1) or dimannoside (PIM2).
What are the official names of this protein?
Phosphatidylinositol mannoside acyltransferase, PIM acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LpxL/LpxM/LpxP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Permanently associated with the membrane.
Protein: GATA_RICPU
Sequence: MTELNKLTVADSIKGLKNKDFTSTELIGAHIKQIEKHRNLNAYVTETFDLALKQAEAADQNYAQNNARTLEGIPFAAKDLFCTKGIRTTACSNILKNFIPNYESSVTQNIFDKGGVMLGKTNMDEFAMGSANITSCFGNVISPWKANDDNADLVPGGSSGGSAAAVSGFMASAALGSDTGGSVRQPASFTGLVGFKPTYGRCSRYGMISFASSLDQAGIFTRSVLDSSIMLEAMMGFDEKDSTSIKAEVPELQSAIGSSMKNMKIGVPLSLGEGSIIEPDIMKMWQDTIELLKNAGAEIVDITLPHAKYGVAVYYVIAPAEASSNLSRYDGIRYGLRVERENMTLDEMYEMTRSTGFGEEVKRRIMIGTYVLSSSGMDAYYLKAQKVRRLVANDFNNAFAKVDAILLPAAPTAAFKIGEKQNDPTIMYLNDLFTIPASLAGLPCASVPAGLSARGLPLGIQIIGKQLDEYNVLKVASTIESGVKHIKFEPKGF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.