PharMolix/UniProtQA huggingface dataset:
Protein: LYPA2_HUMAN
Sequence: MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV
What is the function of this protein?
Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS (PubMed:21152083, PubMed:28826475).  Deacylates GAP43 (PubMed:21152083).  Mediates depalmitoylation of ZDHHC6 (PubMed:28826475).  Has lysophospholipase activity (PubMed:25301951).  Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G) (PubMed:25301951).  Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide (PubMed:25301951).
What are the official names of this protein?
Acyl-protein thioesterase 2, APT-2, Lysophospholipase II, LPL-II, LysoPLA II, Palmitoyl-protein hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_ACTP2
Sequence: MTAANQNYGTGRRKSSSARVFIKPGNGNITIDQRSLDVYFGRETSRMVVRQPLELVELLDKLDLYITVKGGGISGQAGAIRHGITRALMEYDETLRPALRAAGFVTRDARRVERKKVGLHKARRRPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NNR_THEVB
Sequence: MKPTFPAIVTTAEMQAIEGAMFNGGLPIPALMEKVGQRLSHYLQAHFPTSQYPRVAVLAGPGHNGGDALVVARELWHRGYQVKLWQPFERLKPLTADHARYARFLGLPFVERVEALQEVDVIVDGLFGFGLERELTGELAHAIDEINTWPQPRVSIDVPSGLHSDTGAVLGTAIRADRTLCLGLWKRGLLVEEAQPWVGQGVLIPFDIPSVVIETALASAPRRYCLDDSCWQALPLSRSPITHKYQQGQLLLIGGSGQFGGSILLSALAARCTGVGMLVVAVPQSLKSLVLSRVPDAIVVGCPETPRGAIARLPEGLELGKFSAIACGPGLTPEAVSVVATVLRAETSLVLDADALNILATLSPWPLPSGTILTPHYGEFRRLFPDLVGTAGDRLDQVIAAARWSNAIVLLKGARTAIASARGDLWINPHSTPALARGGSGDVLTGLIGGLLAQQEALRATYGGVWWHAQAALEAEQQATSLGVYPEQLIAHLLPTLRRALAARV
What is the function of this protein?
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity).
What are the official names of this protein?
Bifunctional NAD(P)H-hydrate repair enzyme Nnr, Nicotinamide nucleotide repair protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NnrD/CARKD family.
Protein: HIS6_CELJU
Sequence: MPLAKRIIPCLDVDNGRVVKGVKFLDIRDAGDPVEIAKRYNQEGADEITFLDITATHEGRDTTVHTVEKIASEVFIPLTVGGGIRTVDDIRTMLNAGADKVSINSAAVFNPDFVKAASDRFGAQCIVVAIDAKKVSAEGEMPRWEIFTHGGRKPTGIDAVEWAVKMAGYGAGEILLTSMDGDGTKKGYDLGVTRAISDAVPIPVIASGGVGNLQHLVDGVTLGRADAVLAASIFHFREYTLPQAKEFMRAQGIEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_PSESM
Sequence: MSACQTPVIVALDFPTREAAMRLADQLDPKLCRVKVGKELFTSCASDIVEALRGKGFDVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACREVLEQRTGPQPLLIGVTVLTSMEREDLAGIGLDIDPQVQVLRLAALAEKAGMDGLVCSALEAQALKAAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALAAVVAELA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CU01_ANOGA
Sequence: MAFKFVIFAAVVAVARAGLIASPAVSYAAAPALVAAPVAKVAYAAAPIAKVAYAAQPEEYDANPHYSFSYGISDALTGDSKSQQESRSGDVVQGSYSVVDPDGTKRTVDYTADPHNGFNAVVRREPLAAKTIVAAAPVATKVIAQPAVAYAAPVAKTISYAAPVATKTYVAQPALSYAAPLTKTYVSQPALSYAAPVAKTISYSAPLATKTYVSQPAISYAAPLAKTYVSQPALSYAAPAYAYHH
What is the function of this protein?
Component of the cuticle of African malaria mosquito.
What are the official names of this protein?
Cuticle protein.
Protein: DDL_CUPTR
Sequence: MSFVAHPNIDPRSLGKVGVLLGGRSAEREISLMSGNGVLAALQSRGVDAHGFDPGLQGVAELAAAGFDRVFIALHGRYGEDGTIQGLLEQLGVPYTGSGVLASALAMDKQATKRLWMTHGLATPRFAMLHADTDFDAVVADLGLPLIVKPAREGSSIGLTKVTAADQMRAAFDKAAALDNDVIAETFVDGAELTCPVVGEGDTAEALPVIRIVAPEANYDYQNKYFTDDTQYLCPSGLDAEVERQVQALAVQAYRVLGCRGWARADVMLRADGTPFLLEMNTSPGMTGHSLVPMAARAVGISYEDFVLQVLAAATLDLHPNEHWKPE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C71BL_ARATH
Sequence: MSIFLCFLLLLPLFLVFYKRLLPSKGKLPPGPISLPIIGNLHQLGKSLHRSFYKLSQEYGPVMFLRFGVVPVVVFSTKEAAEEVLKTHDLETCTRPKLSATGLFTYNFKDIGFAQYGEDWREMRKLAMLELFSSKKLKAFRYIREEESELLVKKVTESAQTQTLVDLRKALFSYTASIVCRLAFGQNFHECDFVDMDKVEELVLESETNLGSFAFIDFFPAGLGWAIDRISGQHSRLHKAFARLSNFFQHVIDDHLKPWQSEDHSDIVGVMLDMINKESKVGSFKVTYDHLKGVMSDVFLAGVNAGAITMIWALTELTRHPRVMKKLQQEIRELLGDNKEKITEQDLEKVHYLKLVIQETFRLHPPAPLLLPRETMSDVKIQGYNIPKNTMIEINTYAIGRDPNCWTNPNEFIPERFVDSPIDYKGQHFELLPFGGGRRICPGMATGMTIVELGLLNVLYFFDWSLPYGMAIADINMEEAGAFVIAKKVPLELVPVLHY
What are the official names of this protein?
Cytochrome P450 71B21.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL9_RAT
Sequence: MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQPDE
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_PYRST
Sequence: MVKFLKSGKVVVVLSGRFAGKKAVIVRNFDDGTSSRPYGHALVVGLQKEPRKVTKRQSQKKQAKKSTLKTFIKTVNYNHLMPTRYTLDVDFKGVAAEAQENPTKKVEARKECKKLLEEKFKTGKNRWFFTKLRF
What are the official names of this protein?
60S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL27 family.
Protein: GBRB1_BOVIN
Sequence: MWTVQNRESLGLLSFPVMIAMVCCAHSANEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGAGKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTGVGDPKTTMYSYDSASIQYRKPMSSREGYGRALDRHGAHSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH
What is the function of this protein?
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain.  Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).  Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site.  Functions as ligand-gated chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit beta-1, GABA(A) receptor subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: UTP10_CHAGB
Sequence: MASSLAAQLAQIAANSRTSLNAKALKATHSKSLIWEPRVAAGQTFAEIYQLSYEGFEELCNLDARFAQYGASLFSEQSQEADRIQMNAEENAVLDKRVDSFLHLVGSRLRLMPAIKAIEWLIRRFRSLTAPPRAAIVQQATNRPELLSVISQYTLESCRARQEYPGLVSFWGGVMAEAANGMLDKMRSGRRSIQLENDHILLQQIGPVLSEAMVMKEVPGIQIASYMIVTILAAKGSLNDVALTAFMDQLVHGWNIDTYRPGLVCLCILAQHRAAKQVSSRIAKALIKVQDLVPTLVEISRQHRVDKLANGLALAFIERLSKKGDVRSLPAINSLLSANLLRDKQIKVIYKSMLLAAHKVNDEVDEDGHIRKEIGSSLISLSQTGGDVGDVIRSAIEEVDFNIEELELKLGAAIRPKLAIEQSSEEAGAEEGAMAVENTLSLASTFQELAKLQPSTVSCLSQDSSGLFNDLCAVLLSAAAAESDMEKFDSIPALSRPLATSNPFYLSFYMRVWCGPFPTLAKVAALERVKLRLKESDCADKDFQAIIPYCAVALSDPAKKVRRAAADLIAVLGSLVKEQTRQVWGAKDLYGKVGAPNALDRDTLKALVSSVLVPSLEESVLHEAHVVAVLVSALESSKGSSGTEGGRRHLSHATRLSIFKFICGHVTETPLLAVKIRLLRSLNQIRSISGTSRTDLLLPLLRWWAALGHEEVIELTARESLDEATVDQAVVDVIIANHAAGLETAFELINDPKTALRPHLVQAIFCRVIKMWPSMKSDTKSSTARFMFNITQTLSSSEHGPVITEAVELLRKVELTTDIQLDLIDSLQDQVKLATEKPANKRRRVSTTEQSRSVGLQSNPELKAALNKTTFVLELVQESDPANHPELLPSLFTTLSDLHHLSTLIGSELGYLQNLVLSSLLAMMPAYKDNKNLTIDASVGHGDILATCIQKSSSPAVINAALLLVASLARTAPDVVLQSVMPIFTFMGSSEVIPPLIDTFRRRGRNVVASTKDLLASFVTAYEHIPSHRKHDLFISLVQNLGPEDFLFAILAMFVDRYAATDNMISFTTQMMSSFSVEIQLQTLIKLLDLTSDIFKPKPSLSNVLLGGDGSEHDTQKVATKQLNLLPHLLANKRLKREITQLAERDDMETGKIRDLYATLLESILTLATTVKNKKALYNRCGDALSNLLNLLSIAEFIKSVEALLDRPNVGLRQKVLRALELRVDSESTADPRSREALLAFLPQLTAVIRESDDMSYKHTAVTCVDKISEKYGKKDLDAVAAAAATIAGDYCLGQSSQTLRVMALLCLASLVDVLQDGIVPVLPVAIPKALDYLEQSLVGEEPNAELHNAAYAFVAALAQHIPYMITGSYLDRLLACSNASAAAALDDESSSNRTHCLQFLAKLVDPKVMYNALNQNWASASSCGASAVSEYLDILGMALDKHSKAAVAKNVASLSTIFLSAMDLRRTVVSGQAKTAISPSELGEIETKIGDDALKMIYKLNDAAFRPIFSKLMEWASTGLPKNDASGRTLRLFAVYGFLDTFFGNLKSIVTSYASYIVESAVQVLSSTNFQDADEKELWKWVLRTLGKCFEHDQDGFWQAPAHFGAVAPVLVEQFLNAGAADATEDLIPALVELAAAADSQEHHKELNGTLLKHLRNGQAAVRLAVVQCQQALTVRLGEEWLQALPEMLPYISELQDDDDEVVERENRRWIVEIEEKLGESLDSMLQ
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Involved in ribosome biosynthesis (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 10.
What is the protein family that this protein belongs to?
Belongs to the HEATR1/UTP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RIMM_FRATO
Sequence: MSQDFVEIAKIGATYKLNGELNLYPLANSIETLLSYGDWYIQLPATNVWQQLKGESVLKRADKVYIKLANINNADTAKKYVNALIGVPKRALPQLAEDEVYFKDLIGCSVKNINNDSFGVVVDIIETGANEVLVCKEDNSEYLIPYVKQYIVSEDLNSKKIVVDWEYDY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_STAAE
Sequence: MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFNNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLLNTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: COAX_NOCSJ
Sequence: MPLLCADIGNSHTVLGLVSGGSVLADWRVATDERNTADDWSVLLRGLLGAALEEIDGIAVCATVPAVLHEWREMLTRHFPAVRHVVVEPGVRTGVPVLMDNPREVGTDRIINALAAVHEYGGPAIVVDFGGTATTFDVVSAQGQYVGGSISPGIELSLESLGRRGAQLRKVELLRPRSVIAKNTVEALQSGMVFGVAAQVEGIVDRMIGELGVGATDVQVIATGYLAPVVLDECRCFTHHAPWLTLRGLELVFERNA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1583_ARATH
Sequence: MSKPLKFLLWSSLALLLLQIGSGAICEGKSSEPAVRQTQVKWREGKKFRVEVMNKCPMCPIINLRLKCQGFPQSLVDPTFLRVLSSSAGNCVVNDGLPLSPMQTLSFNYSNTHQFALRPLSWSFQCE
What are the official names of this protein?
Uncharacterized protein At1g05835.
Protein: LCMT1_YARLI
Sequence: MNLRKDKVVQSTDGDALSSKYSAVQKGYLQDEFIDLFVAGSKQAAAQQGPGSARKVVAQFQPKLPLINRGTFVRHHAIDVLVDRFLAAKKPGQRVQIISLGAGSDTRPFSLWSSKPENRDEILYHEIDFAVSVERKRDIIMQDSTLRELVGAQEYDKTTGMHTQRYHLHGIDLRSIGPGFVLPGSDPSLATLIISECCLCYLEPDQAKQVIFWITSEFTNSTIVMYEPLSGQDQFGQVMIENLASRGISIPSMTKFPSLESQIERFKAAGYTEVLATSMDVIHDEWLSPEEQQRIHGLEFLDEREELLLLLKHYCVVWASNLTK
What is the function of this protein?
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
What are the official names of this protein?
Leucine carboxyl methyltransferase 1, Protein phosphatase methyltransferase 1, [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: YAEH_SALPB
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDRGEFFAKSVKFKYPRQRKTVVADGIGQGYKEVQEISPNLRYVIDELDQICQRDRSELDLKRKILDDLRHLESVVANKISEIEADLDKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: SYP_RIPO1
Sequence: MRLSQMLFVTLREDPAEAEIPSHKLLLRAGYIRRIGSGIYAYLPLMWRVLQKVSQIVREEMNAAGAQECLLPQLQPAELWRESGRWETYTKAEGIMFSLIDRRDTELGLGPTHEEVITTIAKEMIRSYRQLPVNLYQIQSKFRDEIRPRFGLMRGREFIMKDAYSFHASEDSLKETYQAMDQAYRNMITRCGLEFRAVQADSGAIGGSASQEFMILAEAGEDEVLYTEDGKYAANVEKAVSLPPDAELSPFTTPEKRETPNTNTIEKLCQFLQCSATAIVKNVLYQAVYDNGKTVLVLVSIRGDQDVNDVKLTNELVRLAPQYQATTLLALQVPDETAQAKWAAKPLPLGYIAPNLEDNYISSIPDITPKFLRLVDKTAVELKNFITGANESGYHQVGANWGQEFVLPSLVVDVRKAMAGDRAVHDPIQTLQTARGIEVGHIFQLGVKYSQAMGATFTNEQGEEKPLIMGCYGVGVSRLAQAAVEQSYDKDGIIWPVAIAPYHAVVVIPNINDAQQVEVAEKLYTELNKVGVETLLDDRDERAGVKFKDAELIGIPYRIVTGRSLQSGKVELVERSTKNSQEIAIDQVVETLKKLINV
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX22_YEAST
Sequence: MPPPSRSRINKTRTLGIVGTAIAVLVTSYYIYQKVTSAKEDNGARPPEGDSVKENKKARKSKCIIMSKSIQGLPIKWEEYAADEVVLLVPTSHTDGSMKQAIGDAFRKTKNEHKIIYCDSMDGLWSCVRRLGKFQCILNSRDFTSSGGSDAAVVPEDIGRFVKFVVDSDVEDVLIDTLCN
What is the function of this protein?
Involved in peroxisome biogenesis.
What are the official names of this protein?
Peroxisome assembly protein 22, Peroxin-22.
What is the protein family that this protein belongs to?
Belongs to the peroxin-22 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: FCERG_MACFA
Sequence: MIPAVVLLLLLLVEQAAALGEPQLCYILDAILFLYGIVLTLLYCRLKIQVRKAAIASYEKSDGVYTGLSTRNQETYETLKHEKPPQ
What is the function of this protein?
Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors.  As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells.  As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils priming T-cells toward effector T-helper 2 subset.  Associates with pattern recognition receptors CLEC4D and CLEC4E to form a functional signaling complex in myeloid cells.  Binding of mycobacterial trehalose 6,6'-dimycolate (TDM) to this receptor complex leads to phosphorylation of ITAM, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes.  May function cooperatively with other activating receptors.  Functionally linked to integrin beta-2/ITGB2-mediated neutrophil activation.  Also involved in integrin alpha-2/ITGA2-mediated platelet activation.
What are the official names of this protein?
High affinity immunoglobulin epsilon receptor subunit gamma, Fc receptor gamma-chain, FcRgamma, Fc-epsilon RI-gamma, IgE Fc receptor subunit gamma, FceRI gamma.
What is the protein family that this protein belongs to?
Belongs to the CD3Z/FCER1G family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: KLH36_RAT
Sequence: MEASKQMRVSRPYKISESSKVYHWPGHSTTVLQRLNEQRLHGLFCDVVLVVEEQQVPAHRNLLAVCSDYFNSMFTLGMREAFQKEVELVGTSYVGLKAVVDFLYSSELELDGSNIDYILETAHLLQIWTVVDFCCEYLEQEVSEDNYLYLQELASIYSLKRLDAFIDSFVLNHFSTLSFTPDFLQTVSVQKLCIYLSSGQVQHTWEYDLLQAALQWLTQQPEREVHTCRVLENIRFPLFPEDILLQRVKLAMCSLLPSEANGEGFVEEAMHYHNSLVAQPVLQTKRTLLRSEECLLFVGGEVSERCLELSDDTCYLDTKNEQWVKETSLPARRSHHCVAVLGGFIFVAGGSFSRDNGGNAASNLLYRYDPRRKQWIKVASMNQRRVDFYLASIEDMLVAVGGRNENGALSSVETYSPKTNSWTYVAGLPRFTYGHAGTIYKDFVYISGGHDYQIGPYRKNLLCYDHRTDVWEERRPMTTARGWHSMCSLGDSIYSIGGSDDHMESMERFDVLGVEAYSPQCNQWTRVAPLLQANSESGVAVWQGRIYILGGYSWESTAFSRAVQVYDREANRWSRGPDLPNAIAGVSACVCALNPRLEEKKKKNKDKRQDRGQ
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Kelch-like protein 36.
Protein: HCP_YERPP
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLVAVLQGLSAWALQARELGIIDSQIDSFAPRAFFSTLTNVNFDSDRIVEYAKDAILLRHSLAVRCRLLDSTITVDHPLAELQLVADDIPSLLQQSQQFALNNDKADVGDDIHGLRMLCLYGLKGAAAYMEHAHVLGQSDEQIYAEYHAYMAWLGTQPRDVDTLLNNAMGIGKMNFNVMAILDQGETQAYGDPQPTSVNVRPVAGKAILISGHDLKDLHMLLEQTQGTGINIYTHGEMLPAHGYPELKRYPHLVGNYGSGWQNQQTEFAKFPGPILMTSNCIIDPNVGNYGDRIWTRSIVGWPGVNHLDGDNFAPVIEQALGMAGFPYSELEHLITVGFGRQTLLNAADTVIDLVASKKLRHVFLVGGCDGSRTERSYFTDFARSVPQDCIIMTLACGKYRFNKLDFGTLEGLPRLLDVGQCNDAYAAIMLAVKLSEKLGCTVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIYTGPTAPGFLTDNLMAILYEKFGMQPITTVEQDMQAILGH
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C97D2_MOUSE
Sequence: MHRVPRLTTPWANRDLQRAWEKTYQDHRKKVQNAQPLVDTHPPQIYSHLCLKFKKLKMEEERLSIIDRNNYLLLQRVASAMKTRGQTDGRNNFTQRRS
What are the official names of this protein?
Uncharacterized protein CFAP97D2, CFAP97 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the CFAP97 family.
Protein: ATL65_ARATH
Sequence: MRFVAPPPRSGDNSPSPSPSSGISEEILSRSSDPPLEFSPPLIAMVVVLAAAFLFVTYSRLISRRFLSPLFRRFRRWRCRRRRLLHLSSASSASTSSSDLRSFSPFPFDSFHYSSYSPYGLDDSVIKTLPLFLYSAAACTGKPAVGKTSAANCRDCAVCLLEFEEGDYVRTLPLCFHAFHLECIDEWLRSHPNCPLCRTAILGSAGVLTPMSPFVPLMAPRIRPSLDDEENNAIIIRGEITPSRSNWNTIAADTTNDQEIRASVEEQSSPAISRFRELKRSYSFECERESESERVTMEPATVSPWRYRRSTWNKRQSPFGNLISKSRVFSFRYYRSTKSPFFRRRSSAGVFYPISERIPATGSSSRRTKSMTSPMFFRTAPHSSSRLRCGDPEALLSPERWRRRDTCRAEM
What are the official names of this protein?
RING-H2 finger protein ATL65, RING-type E3 ubiquitin transferase ATL65.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS14Z_MYCVP
Sequence: MAKKALVNKANKKPKFKVRGYTRCNRCGRPHAVFRKFGLCRICLREMAHAGELPGVQKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RK27_PORPP
Sequence: STKNGRDSNAQRLGVKKYGGETVKPGNILIRQRGTKIYPGHNVGMGK
What are the official names of this protein?
50S ribosomal protein L27, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HUTG_PSEPU
Sequence: MDKVLSFHQGRLPLLISMPHAGLRLSDAVRDGLVEEARSLPDTDWHIPQLYDFARDLGASVVAAEYSRFVIDLNRPDDDKPLYAGATTGLYPATLFEGEPLFKEGLAPSGEERKRYLEQIWRPYHGTLRRELDRLREQFGYALLWDAHSIRSHIPHLFDGKLPDFNLGTFNGASCDPVLAERLQGVCAEATGYSHVLNGRFKGGHITRHYGDPAKHIHAVQLELAQSTYMEETEPFTYREDLAQPTQVVLKQLLQALLAWGAERYQR
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-glutamate to formate and L-glutamate.
What are the official names of this protein?
N-formylglutamate deformylase, Formylglutamate amidohydrolase, FGase.
What is the protein family that this protein belongs to?
Belongs to the N-formylglutamate deformylase family.
Protein: SEQA_SHEWM
Sequence: MKYIEVDEELYRLIASKTERIGESASEILRRLLGLEVEASATQEKDEPEVISQPGLEETADVEDKPRFIDLHSSINKEELAAAKGAVGRFLFILEAVYLASPEQFAQVLKIKGRDRLYFATSKQSLLKASKSANPKEIGQSGYWVTTNNNTAKKRTILTEVLHQYGTVEAQIESITRNI
What is the function of this protein?
Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle.  Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins.  Repression is relieved when the region becomes fully methylated.
What are the official names of this protein?
Negative modulator of initiation of replication.
What is the protein family that this protein belongs to?
Belongs to the SeqA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIP_PELRI
Sequence: HSDAVFTDNYSRFRKQMAVKKYLNSVLT
What is the function of this protein?
VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
What are the official names of this protein?
Vasoactive intestinal peptide, VIP, Vasoactive intestinal polypeptide.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.