PharMolix/UniProtQA huggingface dataset:
Protein: CATH_BOVIN
Sequence: MWAVLPLLCAGAWLLGAPACGAAELAANSLEKFHFQSWMVQHQKKYSSEEYYHRLQAFASNLREINAHNARNHTFKMGLNQFSDMSFDELKRKYLWSEPQNCSATKSNYLRGTGPYPPSMDWRKKGNFVTPVKNQGSCGSCWTFSTTGALESAVAIATGKLPFLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYRGQDGDCKYQPSKAIAFVKDVANITLNDEEAMVEAVALHNPVSFAFEVTADFMMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEEKGIPYWIVKNSWGPNWGMKGYFLIERGKNMCGLAACASFPIPLV
What is the function of this protein?
Important for the overall degradation of proteins in lysosomes.
What are the official names of this protein?
Pro-cathepsin H.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: OMH4_SCHPO
Sequence: MLGWNKHVFFSESRINFRCLLRKKLKKRCPLSARFVLVLLLIVLIFILKMGYKQLIYKLNHPPLRRIDERNDPLFSNGCKNVHLEAQLHPRMNATFVMLARNSDLPGVVSSINSLEKHFNRHFNYPYTFLNDEPFDEKFKETILKLTSANVEFGTLEKDTFGFPGNVDVDAAREAIASQGDRGIMYGDTESYHHMCRFFSGFFYKHPLLLKYQWYWRVEPDVAFTCDISYDPFYYMEENGKIYGYVVALKELEDTVPNLFRYTSAYRRNNNLTSNMWKFFLDAPKKENYDISRKDPTVGLSFSSHLNAMIDSSYSAETSSMEGESYNMCHFWSNFEIANFKFFRNEQYENFFRTMDATGGFWTERWGDAPFHSLAAGLFLSKEQVHYFRDLGYRHSDIHHCGQSLGCNCECIPELSEIESTSGGCVTQWVNLIGDGFLDE
What is the function of this protein?
Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins.  Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
What are the official names of this protein?
O-glycoside alpha-1,2-mannosyltransferase homolog 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 15 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: CYB_TARRO
Sequence: MINIRKTHPLMKIINHSFIDLPAPSNISAWWNFGSLLGVCLTIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIMAMVIVHLLFLHETGSNNPTGIDPNSDKIPFHPYYTIKDILGLMFMLLTLLLLALFSPDMLGDPDNFTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILVLLIIPLLHTSNQRSLIFRPISQMLFWMLTANLFILTWIGGQPVEQPYIIIGQLASIMYFLLIIILIPAASILENYLLNPK
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CWP04_ARATH
Sequence: KVPVDDQFRRVNNGGATDTR
What are the official names of this protein?
54 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: TMM69_XENTR
Sequence: MSYLRRCLPLAQQITLLNQPAAPVYSICRQRLFSTSSRSFTKTYLFTLDRPILQSTTSTLSGQHKIHTSAHHFKKRKIQEETQKHELDLLRYDIKALKDAPKPALYLGLAGLIPFVSAPLLMNVTGCYYPEVAFAQVAYGASILSFLGGVRWGFAIPENSPAKPDWMNLTNSTVPALLAWLALLFRDNITEAAVLVIMGLGIALHYDLALLPTYPSWFKALRAILTVVAVFSLVGSLINSSVYPHKSLVSQEP
What are the official names of this protein?
Transmembrane protein 69.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PAX_I02A5
Sequence: MEDFVRQCFNPMIVELTEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERSESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFIPDLYDYKENRFIEIGVTRREVHTYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVNPREAKRQLKKNLKSLEPCADLPTKVSHRTSPALKTLEPMWMDSNRTAALRASFLKCQKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: AMY_BACLI
Sequence: MKQQKRLYARLLTLLFALIFLLPHSAAAAANLNGTLMQYFEWYMPNDGQHWKRLQNDSAYLAEHGITAVWIPPAYKGTSQADVGYGAYDLYDLGEFHQKGTVRTKYGTKGELQSAIKSLHSRDINVYGDVVINHKGGADATEDVTAVEVDPADRNRVISGEHRIKAWTHFHFPGRGSTYSDFKWHWYHFDGTDWDESRKLNRIYKFQGKAWDWEVSNENGNYDYLMYADIDYDHPDVAAEIKRWGTWYANELQLDGFRLDAVKHIKFSFLRDWVNHVREKTGKEMFTVAEYWQNDLGALENYLNKTNFNHSVFDVPLHYQFHAASTQGGGYDMRKLLNSTVVSKHPLKAVTFVDNHDTQPGQSLESTVQTWFKPLAYAFILTRESGYPQVFYGDMYGTKGDSQREIPALKHKIEPILKARKQYAYGAQHDYFDHHDIVGWTREGDSSVANSGLAALITDGPGGAKRMYVGRQNAGETWHDITGNRSEPVVINSEGWGEFHVNGGSVSIYVQR
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase, BLA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUB_METMP
Sequence: MELIVKEESKTDYNYGSDPYNRDIKTLLNTGLVVIDKPSGPTSHEVAAWVRNMLNLVKAGHGGTLDPKVTGALPVALGNTTKCVPIWHIPPKEYVCLMHLHDDAELVDIENIFKEFTGRIHQRPPLKAAVKRSLRIRKIYEIEILEIDGRDILFRTKCQSGTYLRKLVDDMGEALGTSAHMQELRRTISGPFYENEAVYLQDLLDAYIFWKEDGNEEELRKIVKPLEYGLQHLKKIIIKDSAVDAVCHGATLYSSGISKIEKGLGTDEVVLIETLKGEAVAVGKPLMNTKDMLKTEEGEVVEITRVIMEPGIYPRIWKKRNKNDKSKPELKKK
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: Y2290_MYCSJ
Sequence: MSGHSKWATTKHKKAIIDARRGKNFAKLIKNIEVAARTGGGDPGGNPTLYDAIQKAKKSSVPNDNIERARKRGAGEEAGGADWQTITYEGYGPNGVAVLIECLTDNRNRAAGEVRVAMTRNGGNMADPGSVSYLFSRKGVITLEKNGLSEDDVLMAVLEAGAEEVTDLGDSFEIISEPTDLVAVRTALQDAGIDYDSADASFQPSVTVPLDAEGARKVMKLVDALEDSDDVQDVYTNADIPDEILAQLEE
What are the official names of this protein?
Probable transcriptional regulatory protein Mjls_2290.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3A_ANOGA
Sequence: MSRYVQRPENALKRANEFIDVGKKARALDTLQEVFRAKKWNYNWSESIIEPVMFKYLDLCVELKKSHIAKEGLFQYRNMFQLVNVGSLENVIRGYLKMAEERTEQAQQQSSQATVDIDDLDNLATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLKVNSHCETLYHDIARMAFQFCLKYNRKMEFRKLCEKLRKHLEDICKVSSQTANVTISKPETQQLNLETRLHQLDSAIQMELWLEAYKAIEDIHGLMQLSKKTPLPKTMALYYTKLAMVFWKAGNQLFHASALLKLFQLSRDMKKNVTAEEIQRMTTHVLIATLAIPLPSAHPEFDRFIETDKSPMEKAQRLAFLLGLQQSPSRALLLKELIRLNVLQLAAPQFRHLYQLLEVEFDPLNLCDQVQKIVDEIEADPNSVYGQYIQALKDVTLVRLVRQISQVYQTIEFPRLLELAKFADYHHLERILVDCVRHNDMQITIDHRNECVHFGTDLSESQREDHPDGPTLQSMPSEQIRSQLVNMSVVLHRAIATINPNRKKAERERLRAQMVHQYEENADKEHQRILQRQKKIEDRKEYIERMNQEREEEELRLQEEQVRMQKLAEQRRLEAENEERERKRHENELQMMKERNMKEKIEQIKQTATGQKLLKKLDEEEIRKLNTEEIAAREAEERLKERKAHENNLKTQEKKIDYFERAKRLEEIPLIEKYLQDRSVQDKEFWEKQEAARIEAAIAERKNAEACQERLKRMLPDRDVYWQQLKNERGNQFAEKLKQFNQALEEERKRRLADRVVKRREERRMKWLKEKEEERRRIEEELRKQKEEADRIERERRAEERRIQDEKNRQLAEKQLAIAEEVERRRREELEQMKEADGRRERRPAAGPAEPKPEESWRKGPAAAAPANPAADEPKKNVWQGSGRYGPGPRERGGETGPKDKWRTGPEDHEKDGGGAGGMRRGGDMRRGQDDRGPIRRGGGEERGEREDRGPIRRGGGPGDAPAGTGTPRRDDRPGGWFNRDRRDDRRDDRRDDRRDDRRGDDRGPRGGGERGNTWRRGPADNADDNRRGPRDEGRQDTWRNTRQDAAPKQKEDRPQREARPAQENVPPRSNAGPDEEGWTDVKHR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAC_STAAR
Sequence: MAKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_CLOK1
Sequence: MGSIVKIRDVKLGEGIPKIAVPLVGSNEEEIMEEIAGVKTTKLDIVEWRIDYYKYVEEVEKVKKLLQKMRKNLNNIPILVTFRTAKEGGKREISLEYYIELNKAIAATGNTDMIDIELFAAEDEAVKKIVEELHEYNIKVIMSNHDFHKTPHKDELISRMCRMQQLGADIAKIAVMPCSTKDVLELLSATCEMKCKHNDTPIITMSMGTLGVITRLAGETFGSALTFGSAKAASAPGQLEVNELYKVLKLISAYR
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: KUP_MYXXD
Sequence: MLQARVQLKRGFVKATTTGVPGGEDVKKGPDTFKRSALLALGALGIVYGDIGTSPLYALRECFTGAHGIPPTPANVLGVLSLIFWSLIIVVSVKYLLLVMKADNRGEGGILAMMALVMQRQRAQPSHRSRPMLITLGIFGAALLYGDGIITPAITVLSAVEGLHVATAVFDPYVIPIALVILVALFLVQRHGTADIGAVFGPVMCIWFLTLAGLGVKELVHNPAVLGALSPWHAVELFRHNHLHGFLVLGGVFLVVTGCEALYADMGHFGRKPIQLAWFSMVLPALMLNYLGQGALLLRDASAARNPFFLLAPSWLLYPLVALATVAGVIASQALIAGVFSLTRQAMQLGYSPRMEVVHTSAEEMGQIYLPGLNWALLVGVVALVLGFRSSSALASAYGIAVSTAMVITTLMAYVVARELWGVRRWVAIPVVGLFLSVELAFFGANAVKVADGGWFPLLMAVVVFTLMTTWKRGRDILAAKLRASSIPLKVLLGSFGDHPPVRVPGTAIFMTGNAEGTPPALLHNLKHNKVLHEQVVLLTILSEELPHVPHSERVEVEPLEQGFVRVVARYGFMENPGIPDVLKRCREKGLQFQLMGTSFFLGRETLIPTKRPGMAVWREALFAWMSRNARSATAYFRIPPNRVVELGAQVEL
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBP4_ASHGO
Sequence: MPHIQESRVWCRSISQLSHLAEQFVTENGTESTDMKLLLQQCVDTLSNYQDECKKIKSVSKPVPSKELYDLYETAYVYFKIVSLIVLNKIPKLEEYARAKSDAVDRTGKQLLEIYNMLVNRLVKDDRIAEIKRFVKENSRRDPEAKNEQIGVESGKSIPATLLRNLLMGPSASGTVLLVDVRPRLDFMRCHIKSSSIICIEPVSFKESYTDIDLGKKSMITSPDAEIALFQDRDKFDYIVVYTQDSEKNKHNVQQQQLLVDLLINRSFEKALDRTKVFILAGGFSEWSNAHPDFCVSSQGDSVYLNGDTSGLSLQLMPQTTPQKQYNNMFQTMLSGPTDVHGIIRNPHNFPTQQKSKLKRVPSFRDYFRSSSSSSNINERPGSVPPQLSNGSTIYPETPKLMTNDEYMKSLPQLSPITARAITSPSRALSAVGVSKSSASNSISSLLANSGSASPMKPPDTPLPFTDSIKTLGQQNLTVAVSNLNFSVGLVNCGNSCYMSCIIQCLLGTQELCTMFLNNSYQNHINLNSRLGSKGLLARYFSQLIHQMYQYGKDIRKKMGNEKTAVIPTQFKIACGSINSSFKDNTQQDCQEFCQFLLDGLHEDLNQCGNNPPLKELSEEAEKMREMMPMRLASAIEWERYLTTDFSVIVDLFQGQYASQLQCKVCQRTSTTYQPFSVLSVPVPSTRTCTLTDCFTEFTKIETLEQEEQWSCPSCKKRQPSTKKITITRLPRNLIIHLKRFDNMLNKNNVFVSYPSVLDLTAFWANDYDKKVTNNNVELPSRGQVPPFNYQLYGIACHDGTLRAGHYTAYVNKGAVLGWCYYDDTNWRQIRSAREYITQNAYVLFYHRIHST
What is the function of this protein?
Ubiquitin thioesterase that acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole.  Removes also ubiquitin from soluble proteins targeted to proteasomes.  Is essential to maintain a normal level of free ubiquitin.  Required for promoting coordination of DNA replication and avoids DNA overreplication (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 4, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Late endosome membrane; Peripheral membrane protein.
Protein: DFB11_RAT
Sequence: MRTLCSLLLIGCLLFSYDTPVVGFLRRSVSGFQECHSKGGYCYRYYCPRPHRRLGSCYPYAANCCRRRR
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 11, BD-11, Defensin, beta 11.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARCA_MYCGI
Sequence: MTDAPLGCNSEVGTLRAVILHRPGAELQRLTPRNNDTLLFDGLPWVARAQQEHDAFADLLRSRGVEVLLLGDLLTEALDKSGAARMQGISAAVDARRLGAPLAQELSAYLRTLEAAPLARILMAGMTFDELPFGENELSLVRRMHHGGDFVIDPLPNLLFTRDSSFWIGPRVAITSLSMHARVRETSLTDLIYAHHPRFLRVRRAYESRSAPIEGGDVLLLAPGVVAVGVGERTTPAGAEALARSLFDDDLAHTVLAVPIAQERAQMHLDTVCTMVDTDAVVMYPNIQDSLTAFPIRRKSGGVTIDRAAPFVDAAADAMGIGKLRVIDTGLDPVTAEREQWDDGNNTLALAPGVVVAYERNTETNARLADSGIEVLPIAASELGTGRGGPRCMSCPAGRDPL
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_STRZJ
Sequence: MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYADSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFFPDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPRA_MYCTU
Sequence: MRPYYIAIVGSGPSAFFAAASLLKAADTTEDLDMAVDMLEMLPTPWGLVRSGVAPDHPKIKSISKQFEKTAEDPRFRFFGNVVVGEHVQPGELSERYDAVIYAVGAQSDRMLNIPGEDLPGSIAAVDFVGWYNAHPHFEQVSPDLSGARAVVIGNGNVALDVARILLTDPDVLARTDIADHALESLRPRGIQEVVIVGRRGPLQAAFTTLELRELADLDGVDVVIDPAELDGITDEDAAAVGKVCKQNIKVLRGYADREPRPGHRRMVFRFLTSPIEIKGKRKVERIVLGRNELVSDGSGRVAAKDTGEREELPAQLVVRSVGYRGVPTPGLPFDDQSGTIPNVGGRINGSPNEYVVGWIKRGPTGVIGTNKKDAQDTVDTLIKNLGNAKEGAECKSFPEDHADQVADWLAARQPKLVTSAHWQVIDAFERAAGEPHGRPRVKLASLAELLRIGLG
What is the function of this protein?
Transports electrons between ferredoxin and NADPH.  May supply electrons to P450 systems (PubMed:12071965).  The enzyme can use both NADPH and NADH as a reductant, but the catalytic efficiency is two orders of magnitude higher with NADPH (PubMed:12071965).
What are the official names of this protein?
NADPH-ferredoxin reductase FprA, NFR.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
Protein: FC9_PHOAM
Sequence: MIELGQSYSTIQAMTKQKPLKSLRQRVKENQTPPNRSQNHLGILRPSFSQHSRERKMLHSTSWLDGLRGISATCVVVHHCTLQWFGWHIHEPWFPGQSFLKLPVIRLLISGSPHVYIFFVISGYSLSYKPLKLSRQGRFDEAASVLSSSIFRRHARLFVPTTIVTFFCAIMTQLNWYGKAEHMPGVAVPAWEPPHLDNIWAQLNNFAWNELLFMDPVGRTVAKGDPGEQVKQLHNPYDYVLWTLPVEFNSSMVLLMFLMAFSRVESRARMAFCLAMAVLFQCFFIYWALFLFFSGMLICDLRLELGEALSTRAPSKDTRSWSKHLFVRAIGVGCFVLSLCALSTPHLAFGGREAPGFVTLASMIPERFGDQLLMPIAAIGLVLTLDHHPFLQVLFTNSFAQYMGRISFALFLVHGPLLNTLGHALGRRFIALIGGDTEERYLVAISLTAMVFWLMTILLADFVYQYVDLASVQVSKWAYQRLLRTEEQPGKYEWKSR
What is the function of this protein?
O-acetyltransferase; part of the 2 gene clusters that mediate the biosynthesis of fusicoccins, diterpene glucosides that display phytohormone-like activity and function as potent activators of plasma membrane H(+)-ATPases in plants by modifying 14-3-3 proteins and cause the plant disease constriction canker (PubMed:22870285).  The first step in the pathway is performed by the fusicoccadiene synthase PaFS that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylgeranyl diphosphate (GGDP) and successively converting GGDP into fusicocca-2,10(14)-diene, a precursor for fusicoccin H (PubMed:17360612).  The second step is the oxidation at the C-8 position by the cytochrome P450 monooxygenase PaP450-2 to yield fusicocca-2,10(14)-diene-8-beta-ol (PubMed:22870285).  The cytochrome P450 monooxygenase PaP450-1 then catalyzes the hydroxylation at the C-16 position to produce fusicocca-2,10(14)-diene-8-beta,16-diol (PubMed:22870285).  The dioxygenase fc-dox then catalyzes the 16-oxydation of fusicocca-2,10(14)-diene-8-beta,16-diol to yield an aldehyde (8-beta-hydroxyfusicocca-1,10(14)-dien-16-al) (PubMed:21299202, PubMed:22870285).  The short-chain dehydrogenase/reductase fc-sdr catalyzes the reduction of the aldehyde to yield fusicocca-1,10(14)-diene-8-beta,16-diol (PubMed:21299202, PubMed:22870285).  The next step is the hydroxylation at C-9 performed by the cytochrome P450 monooxygenase PaP450-3 that leads to fusicoccin H aglycon which is glycosylated to fusicoccin H by the O-glycosyltransferase PaGT (PubMed:22870285).  Hydroxylation at C-12 by the cytochrome P450 monooxygenase PaP450-4 leads then to the production of fusicoccin Q and is followed by methylation by the O-methyltransferase PaMT to yield fusicoccin P (PubMed:22870285).  Fusicoccin P is further converted to fusicoccin J via prenylation by the O-glucose prenyltransferase PaPT (PubMed:22287087).  Cytochrome P450 monooxygenase PaP450-5 then performs hydroxylation at C-19 to yield dideacetyl-fusicoccin A which is acetylated to 3'-O-deacetyl-fusicoccin A by the O-acetyltransferase PaAT-2 (PubMed:22870285).  Finally, a another acetylation by the O-acetyltransferase PaAT-1 yields fusicoccin A (PubMed:22870285).
What are the official names of this protein?
O-acetyltransferase PaAT-1, Fusicoccin A biosynthetic gene clusters protein 9.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SC6A2_MOUSE
Sequence: MLLARMNPQVQPELGGADPLPEQPLRPCKTADLLVVKERNGVQCLLASQDSDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHSWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCVVTISTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYTYPPWANWVGWGIALSSMILVPAYVIYKFLSIRGSLWERVAYGITPENEHHLVAQRDVRQFQLRHWLAI
What is the function of this protein?
Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (PubMed:16269905).  Can also mediate sodium- and chloride-dependent transport of dopamine (By similarity).
What are the official names of this protein?
Sodium-dependent noradrenaline transporter, Norepinephrine transporter, NET, Solute carrier family 6 member 2.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL11_THEVO
Sequence: MAQSVKTMVEGGKATTGPPIGPALGPLGLNVAQVVKEINEKTKEFQGMQVPVTVTVIDPETKKYEITVGVPPTSALLKKELGLEKGASKKKEAVAGNATLEQIKNVAIKKMPSMLAKDLKSAVLEVLGTCVAMGINVEGKDPKEVQKLIKSGQIKIEQ
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: MIAA_CUTAK
Sequence: MRKNEYVNLPVICLVGPTASGKSGLAVRVCRRLYVDEHPAEIINTDSMVVYRGMDIGTATPTLREQRTVVHHLVSILDVTVPSSLVLMQTLARDAVEDCLSRGVIPVLVGGSALYTKAIIDEMSIPPTDPEVRARWQEKLDAEGPRVLHDELARRDPKAAESILPGNGRRIVRALEVIDLTGSFTATIPDGTLHWPKTVQMGLELSRKDIDQRIADRVDQMWAYGFVDEVRSLANVGLREGLTASRALGYRQVLEYLNGDYDEDEARRRTIIGTRRFARKQLMWYRRDDRIEWFNALAPDLDDRVVARVLTALTTDEED
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CH10_CAUSK
Sequence: MKFRPLGDRVLVKRVEEETKTKGGIIIPDTVKEKPQEGEVVAVGPGARNDKGDIVALDVKAGDRILFGKWSGTEVKVDGQDLLIMKESDVLGIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.