PharMolix/UniProtQA huggingface dataset:
Protein: PRMB_RHOJR
Sequence: MAPRPLRRHPPLHHSFHESRRDPVADKHRINFEPVDIEMEVGEDEYILDAAFRQGIHLMHGCREGRCSACKSFVLEGDIQMEDYSTFACNDAEVDEGHVLLCRSTAYSDCTIELLNFDEDELLGGVPIQDVRTRVTRIEPMTKDIVSLRLAPVEPAGYEFKPGQYSDLHIPGTEEHRSFSMATTRSTPGHVEFLIKKYPGGKFAGLLEDGISVGDEIALTGPYGSFTIKEGHVLPMVFIGGGAGMAPLLSLLRHMSETGNTRQVHFYYGARTPQDLFYVDEILELGRGLTDFTFVACLSESMDPPPVGAIAVEDGNVTDVVGRREPDIGRAEVYLCGPPPMVDAALELLEANGTPKDQIFYDKFTSPAFE
What is the function of this protein?
Reductase component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane.  Reductase catalyzes the transfer of electrons from NADH or NADPH to monooxygenase (Probable).
What are the official names of this protein?
Propane 2-monooxygenase, reductase component, PrMO.
What is the protein family that this protein belongs to?
Belongs to the TmoA/XamoA family.
Protein: PANC_BURVG
Sequence: MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQNENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFAGVCTVVTKLMSCVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIIAAETVRDEDGLALSSRNRYLTADERTEAPELVKTLQRVRESVLGGERDLGKLEQHARAHLAERGWAPDYIAIRRRANLIAPSAAELEAGEPLVVLAAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_KLEP7
Sequence: MNPIVINRLQRKLGYTFHHQELLQQALTHRSASSKHNERLEFLGDSILSFVIANALYHRFPRVDEGDMSRMRATLVRGNTLAEIAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQNVERLILSWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENT7_ARATH
Sequence: MTNPEDIPSRIEGKNVARLVCCFLGVGSLVAWNAMLTITDYYYQLFPKYHPSRVLTIVYQLVANVFIITLATKEAKLNTRLRNIFGYSLYTAGTFCLIILDLASHGSGSVVAYVLLCLIVALFGLADAFVQGAMVGDLSFMSPDFIQAFMAGLGIAGALTSVLRLITKAIFDNSPDGLRKGALLFIGIATLIELACVFLYTLVFAKLPIVKYYRAKAGKEGAKTVSADLAAAGLQEQAEQVHQMDESKIQKLTKKQLLRENIDLGINLSLIYVVTLSIFPGFLYENTGEHRLGDWYAPVLVAMYNGWDAISRFIPSIKPLAMESRKWITVCVVARLLLVPAFYFTAKYADQGWMLFLTSFLGLSNGYLTVCIFSTAPKGYNGPEANALGNLMCVFLLGGIFAGVCLGWLWLIGNDSF
What is the function of this protein?
Nucleoside transporter that can mediate uptake of adenosine, uridine, guanosine or cytidine when expressed in a heterologous system (yeast).
What are the official names of this protein?
Equilibrative nucleotide transporter 7, AtENT7, Nucleoside transporter ENT7.
What is the protein family that this protein belongs to?
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Plasma membrane.
Protein: PSBA_CHLVU
Sequence: MTAILERRESASLWARFCEWVTSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSNAIGLHFYPIWEAASLDEWLYNGGPYQLIVCHFFLGICSYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFIIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAVVEAPAVNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARLY1_ALKCK
Sequence: MVGRLKESPSQEMIDLLFKPSIRSDLKHHYSYLLKINSVHLFMLKSEGIISDEAASKIHSVLTHLQVTGKEALSINPALEDLYFNVEAYIIEQTGPEIGGQMHTGRSRNDILATVTRMRIREEMLEIYELVCTLRRTLIDLATEHTSTLMTGYTHLQPAEPITFAHYLSALLHGFERDFTRLYNCYAHINKSPLGSCALASTTFSINRKFTMELLGFADLLENSLDGIASRDYALEALSALSIFSNSLSRFAQDLYTWCSYEFGYLEVGHSVAVISSIMPQKKNPVTLEHIKAKAGHIQGALVSSLSVLKNTLYSHSRDTSMESMKYTWEAINETKAAIRLMIKTLQTLTVHKDNMAATTRQNFSTVTELANALVRHYHFSFRTAHHIVAEIVNETLNQGLGSDKIEASTVERAIKQVTAKTVSVTKEFVEQALDPERNISLRTVRGGSAPVEVARQLQQLEQTLASDHQKISDLKQALQSADQLYKHYAAELERGAQ
What are the official names of this protein?
Argininosuccinate lyase 1, ASAL 1, Arginosuccinase 1.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_SHIB3
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MINE_SALSV
Sequence: MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: NDK_XYLF2
Sequence: MVLERTLSIIKPDAVAKNVIGDIYSRFEKAGLKIVAAKYKQLSRREAEGFYAVHRDRPFFNALVEFMISGPVMIQVLESENAVARHRELLGATNPKDAAPGTIRADFAESIEANAAHGSDSVENAAIEVAYFFAATEIILR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCND_OSTTA
Sequence: MNRSRTSSFSTDRSASTVALAPDGDYERERVSALASWPEYAVDALRSEQDFIVHQSAALWTHRTPALHDPDSQETQLDVAKGLLARERETHGSFVFDARAAHHCAFRSQLVEWILDVCAGERFGPTTADVAIAYTDRVLSKTVVPKTSLHLVALCCLHIAVKYEEIEERVPTMSKLRSWTSNMYSPEIIRKMELAVLIELGWDLGVLTPAHFLESFLALTNGGISDGDDIEHGDAYKERYREELRYFVCQLYSLCVQDTSLLNQPPSQIASAVIATARVHLGVKPMCSPELRAAGNVTPQQIYPLVAHMLKLWDEACAEDEAMDEVETSAEFNSLTIQVPKPIGHDIVSKMGYEHRVTENASPTCPFDMQWDEE
What are the official names of this protein?
Cyclin-D.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
Protein: THIC_CLOPS
Sequence: MNYTTQMDAAKKGIITKEMQVVAEKEGINIETLMNLMAEGKIVIPANKNHKSISAEGVGQGLKTKINVNLGISKDCANIELELEKVKKAIDMNAESIMDLSNYGKTYDFRKRLVEVSTAMIGTVPMYDVVGFYDKELKDITVDEFFDVVEKHAKDGVDFVTIHAGLNRETIETFRRNKRLTNIVSRGGSLLFAWMELNNRENPFYEYFDRLLDICEKYDLTLSLGDACRPGSIADATDAVQIKELITLGELTKRAWERNVQVIIEGPGHMAMNEIEANVLLEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAMAASYGADFLCYVTPAEHLRLPNLEDVREGIVATKIAAHAADIAKGISGARDIDNKMSDARKRLDWDEMFSLAIDSEKAIRYRKESTPEHKDSCTMCGKMCSIRNMNKILEGKDINLLRED
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: GUDD_ACIAD
Sequence: MAASTPIIQSVRAIPVAGHDSMLLNLSGAHAPYFTRNLLVIEDNSGNIGVGEIPGGEKILATLNDAKSLILGQPIGEYKNLLKKIHQTFADRDSGGRGNQTFDLRTTVHVVTAYESALLDLLGKHLNVNVASLLGDGQQRDEVEVLGYLFFIGDRKQTSLDYATSTHLNHDWYQVRHEKALTPEAIQRLAEASYDRYGFKDFKLKGGVLHGEQEAEAVTAIARRFPDARVTLDPNGAWYLDEAIGLGKHLKGVLAYAEDPCGAEQGYSSREIMAEFKRATGLPTATNMIATDWREMSHSIQLQAVDIPLADPHFWTLEGSVRVSQLCNMYNLTWGSHSNNHFDVSLAMFTHVAAAAVGNVTAIDTHWIWQEGTDHLTKQPLEIKGGKIQVPSVPGLGVELDWDNINRAHELYKAKGLGARNDADAMQFMVPNWKFDHKKPCLVR
What is the function of this protein?
Catalyzes the dehydration of glucarate to 5-keto-4-deoxy-D-glucarate (5-kdGluc).
What are the official names of this protein?
Glucarate dehydratase, GDH, GlucD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.
Protein: YOP1_ASHGO
Sequence: MAEIAGNLQRILQSLDRQFAGNKYLQEFERKTGFPKSYAIAGAGVAYLFIIFINVGGVGEILSNFLGFVLPCYYSLHAIKTTTTADDTELLTYWIVFAFFSVIEFWSKAILYWVPFYWFFKTIFLIFIALPQLGGASLIYHRVIAPLTDPYIAAGSQRKASGISSKMEQAAKGASARATGAASHQSSD
What is the function of this protein?
Required to generate and maintain the structure of the tubular endoplasmic reticulum network and the vacuole.  Induces high curvature in membranes and causes membrane tubule formation.  Involved in membrane/vesicle trafficking.
What are the official names of this protein?
Protein YOP1.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: DLTA_STRZT
Sequence: MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDSLAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEVAEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTTGKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGTLFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDGEELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADSPTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGTMTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLLAYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKGLINEVNKR
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNPO_HUMAN
Sequence: MTCWLRGVTATFGRPAEWPGYLSHLCGRSAAMDLGPMRKSYRGDREAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRRGLPTGDSPLGPMTHRGEEDWLYERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine-5'-phosphate oxidase, Pyridoxamine-phosphate oxidase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: PURQ_THERP
Sequence: MRFAVVTFPGSNGDHDALMAIRLGLGHAAELVWYTETDLSRFDCIIIPGGFSYGDYLRAGALARFAPVMSAVAREAEAGKPILGICNGFQILTEARLLPGALLRNASLEFVCDWVWVRVEQTRTPWTSQLAPGTLLRLPIAHGEGRYYVEAEELVALETNGQVVFRYVDADGLPTADANPNGSVANIAGVCNERGNVVGLMPHPERAYDRFVGGDDGLRILASVLSVGLEVAHSPR
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_NOSS1
Sequence: MIQTHSEVKRVEELRRLLQQASYAYYVSDAPIMEDAVYDQLYRELQQLEIQHPELVTPDSPTQRIGERPATQFLSVRHNIPLYSLENAFNVEELQAWDQRWRRQVAPTEAEYVAELKIDGSAIALTYQNGILVRGATRGDGVTGEDITQNVRTIRSIPLRLNFDGIEKVEKVEVRGEAFLPLEVFKQINEERQKAGEQLFANPRNAAAGTLRQLDSRIVARRRLDFFAYTLHISGMDDASIANTQWEALELLQKMGFRVNPNHKLCQSLAEVADYYKYWDTERLNLPYMTDGVVLKLNSFKLQEQLGFTQRFPRWAVALKYPAEEAPTRVENIAVNVGRTGALTPLAQMRPVQLAGTTVSRATLHNSDRIAQLDIRIGDTVIVRKAGEIIPEVVRVIKELRPADTQPFIMPTHCPVCGQPVVRETGEAVTRCVNASCPAILKGSIEHWVSRDALDIKGVGEKLVYQLVDKGLVHSVADLYDLTTERLFALERMGEKSAQKLIEAIAQSKNQPWSRVLYGLGIRHVGSVNAQLLSEKYRAVAELSSAKQSDIEGIYGIGAEIAQSVYQWFRINANQSLIERLQAAGLKLANTEEIPVMNNGILKLNGKTFVVTGTLPTLKRDEVKALIQKAGGKVTDSVSKKTDYLVVGEDAGSKLEKAQALGIAQLTETQLLEILEE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ATP8_BOSIN
Sequence: MPQLDTSTWLTMILSMFLTLFIIFQLKISKHNFYHNPELTPTKMLKQNTPWEAKWTKIYLPLLLPL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: ARGC_CAMC5
Sequence: MPAINVGIIGVSGYTGFELIRLLLAHPNFKMSYLAASSEAKIDEIFPSLRGVLDLDVHRADAKEAAKRCEVVFLALPHQEAMRYAKQLLSLGVKVVDLSADYRLSRELYEKNYCEHLDVQNLARAVYGLVELNRERIKGANLVANPGCYPTASILAVLPFLKFIDLDFGVVIDAKSGVSGAGKKLSASSHFVSVNENANAYNPINHRHADEIKFHLSNAAGSDISTLFVPHLLPITRGMLVSAYARLVKDIKPLEVLGEFYKNERFIRVRDEAVQIKNVAGTHFCDITAFAHEGKIFINSAIDNLLRGASSQAIANANLMCGLDENLALPMISQFC
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_BURTA
Sequence: MIRTDAKDGALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVRDALKRRFPQWSHKLGDDHMIDLSVLGAISDTAMTRAIEIETASNGLPNTFVPGRNLLFMTIGAAIAYRRGLRALVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRFVLETPLMWLDKADTWRLAEQLGGKPLVELIRVETHTCYVGERSELHDWGFGCGECPACKLRKRGFEAYLRGESVTQAPV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RSGA_LACJO
Sequence: MKKAEGTIISAISGYYDVEIDNKVVRTRARGVFRDRKQKPLVGDRVVVQLDDQGMNYLIEILPRINEIGRPAVANVSRVLLVISAVEPDFSLELLDRYLTFFAWKNVGVVIYLSKSDITSSERLKDIQTELEYYQRIGYPVFEDAEKLENELPKMIDKDQIWTLAGQSGAGKSTLLNQLESEAKQVTGAISTALNRGKHTTRQVTLFKYGSGFIADTPGFSAIDLFKIKVDDLRNYFYDLKEASANCKFRGCQHIKEPGCEVKKLVEEGKIARSRYESYLKIRQEISDNRMPEYLKK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBL_NEUCR
Sequence: MSTPNSDSPAAQAAKKVFSRLDLDGHNLPPSPAPSSPHNGRRYALATELVYTETKDQYGASSIPIYQSATFKQSSSNGGSEYDYTRSGNPTRTHLERHLAKIMNANRCLSVSSGMGALDVITRLLKPGDEVITGDDLYGGTNRLLTYLKNNQGVIVHHVDTTNVESVRQIISPKTTMVLLETPTNPLIKICDIPTIARITHEANEKAVVVVDNTMLSPMLFNPLDVGADIVYESGTKYLSGHHDIMAGVIAVNDTELGDKLYFTINATGCGLSPNDSFLLMRGVKTLAIRMEKQQANAQRIAEFLESHGFKVRYPGLKSHPQYDLHWSMARGAGAVLSFETGDVALSERIVEAARLWGISVSFGCVNSLISMPCRMSHASIDAKTRAERQMPEDIIRLCVGIEDADDLIDDLSRALVQAGAVTLTVDGFHANTAEGAAAAAAGSEAAETTTTAAPSL
What is the function of this protein?
Involved in de novo synthesis of methionine.
What are the official names of this protein?
Cystathionine beta-lyase, Cysteine-S-conjugate beta-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACYP_LACPL
Sequence: MRAVTLKATGRVQGVGFRWATKVAADKCGVNGIVRNLMDGSVFIEAEGEDQRVQVFIDVVRQSPTDFGKVKHLEVHEVEPQNYHDFRITN
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: Y2048_YERP3
Sequence: MKHNLNAHEARVIGCLLEKQVTTPEQYPMSLNGLTLACNQKTSRDPVMELSESQVQQTLDFLLKKHLIRSQSGNRVMKYEHRFCNSEFGDLKFSPAEVAVITLLLLRGAQTPGELRTRTNRMYEFADVAETEETLKTLSLREDGPFVVRLAREPGKRESRFMPLFSGDVASSLLAAGEAEENNHTLEANPRETHSFENIALEKTALEARVAQLEQQVIQLSRRLDDVLIQLDD
What are the official names of this protein?
UPF0502 protein YpsIP31758_2048.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: DER_CHLCV
Sequence: MLRIAILGRPNVGKSSLFNRMCKRSLAIVNSQEGTTRDRLYGEIRGWSVPVQVIDTGGVDKDSEDHFQKHIYKQALAGANEADILLLVVDIRCGITEQDAELAKMLLPLNKPLILVANKADTFKDEHRIHELYKLGISEILAVSASHDKHIDKLLQRIKTLGNVPEVVEEFSEEEVEEEAVPSMELLSKEPLSDYEEEEIPFSTTSAPDKPLKIALIGRPNVGKSSIINGLLNEERCIIDNVPGTTRDNVDILYSHNDRSYLFIDTAGLRKMKSVKNSIEWISSSRTEKAIARADVCLLVIDAQHHLSSYDKRILSLISKHKKPHIILVNKWDLIEGVRMEHYIRDLRATDVYIGQSRILCISAATKRNLRHIFSSIDELYETVSSKVPTPVVNKTLASTLQKHHPQVINGRRLRIYYAIHKTATPFQFLLFINAKSLLTKHYECYLRNTLKSSFNLYGIPFDLEFKEKTKRTN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: DF108_ARATH
Sequence: MTSLIAFLFTVLVIVSSVHCRMTTASTPGYGIKQEDRLCIQGQEGTKLCSSGTSRDCLNFCLIRGYAGGSCYAYTLDQCCCRIPPPKLK
What are the official names of this protein?
Defensin-like protein 108, Low-molecular-weight cysteine-rich protein 51, Protein LCR51.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIOX1_HUMAN
Sequence: MDGLQASAGPLRRGRPKRRRKPQPHSGSVLALPLRSRKIRKQLRSVVSRMAALRTQTLPSENSEESRVESTADDLGDALPGGAAVAAVPDAARREPYGHLGPAELLEASPAARSLQTPSARLVPASAPPARLVEVPAAPVRVVETSALLCTAQHLAAVQSSGAPATASGPQVDNTGGEPAWDSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRVPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRWEAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLEEPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKGLLLTKMPLALN
What is the function of this protein?
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase (PubMed:23103944).  Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity).  Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2) (By similarity).  Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity).  Also catalyzes demethylation of non-histone proteins, such as CGAS: demethylation of monomethylated CGAS promotes interaction between CGAS and PARP1, followed by PARP1 inactivation (By similarity).  Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216', thereby playing a role in ribosome biogenesis (PubMed:23103944).  Participates in MYC-induced transcriptional activation (PubMed:17308053).
What are the official names of this protein?
Ribosomal oxygenase 1, 60S ribosomal protein L8 histidine hydroxylase, Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, Myc-associated protein with JmjC domain, Nucleolar protein 66, hsNO66, Ribosomal oxygenase NO66, ROX.
What is the protein family that this protein belongs to?
Belongs to the ROX family. NO66 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Granular part of nucleoli. Nucleoplasm, nucleoplasmic foci, some of them associated with nucleoli.
Protein: AROQ_NITEU
Sequence: MAANILVIHGPNLNLLGRREPAVYGQTTLEDINRNLTVKAQAAPVALSIFQSNAEHELIDRVQGAMSDGTDFIIINPAALTHTSIALRDALAATSLPFVEIHLSNVYARESFRRTSYFSDIAVGVISGLGAAGYELALQFALTR
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.