PharMolix/UniProtQA huggingface dataset:
Protein: DTNB_HUMAN
Sequence: MIEESGNKRKTMAEKRQLFIEMRAQNFDVIRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIYYQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYTEHSVRTCFPQQRKIMLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNYQLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTREPPHPVFPEQPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYVARLQHCARVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQATGSPHTSPTHGGGRPMPMPVRSTSAGSTPTHCPQDSLSGVGGDVQEAFAQGTRRNLRNDLLVAADSITNTMSSLVKELHSAEEGAEEEEEKMQNGKDRG
What is the function of this protein?
Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids (By similarity).  May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation (PubMed:27223470).  May be required for proper maturation and function of a subset of inhibitory synapses (By similarity).
What are the official names of this protein?
Dystrobrevin beta, DTN-B, Beta-dystrobrevin.
What is the protein family that this protein belongs to?
Belongs to the dystrophin family. Dystrobrevin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Postsynaptic density. Cell projection, dendrite. Basal cell membrane. Postsynapse. Nucleus. Note=Localized at inhibitory synapses on the dendrites of cerebellar Purkinje cells.
Protein: NOMT2_NARAP
Sequence: MGASIDDYSLVHKNILHSEDLLKYILETSAYPREHEQLKGLREVTEKHEWSSALVPADEGLFLSMLLKLMNAKRTIEIGVYTGYSLLTTALALPEDGKITAIDVNKSFFEIGLPFIQKAGVEHKINFIESEALPVLDQMLQETKEEDLYDYAFVDADKSNYANYHERLVKLVRIGGAILYDNTLWYGSVAYPEYPGLHPEEEVARLSFRNLNTFLAADPRVEISQVSIGDGVTICRRLY
What is the function of this protein?
4'-O-methyltransferase converting norbelladine to 4'-O-methylnorbelladine (By similarity).  4'-O-methylnorbelladine is a precursor to all Amaryllidaceae alkaloids such as galanthamine, lycorine and haemanthamine, and including haemanthamine- and crinamine-type alkaloids, promising anticancer agents (By similarity).
What are the official names of this protein?
Norbelladine 4'-O-methyltransferase 2, NpN4OMT2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: RL2_BUCBP
Sequence: MAIIKCKPTSPGRRHAIKVVNPSLYKGKPISSLIRKNSKSGGRNNCGRITTRHIGGRHKRFYRIIDFKRNKDNIPAIVERLEYDPNRSSNIALILYSDGDRRYILASKGLMVGSKIVSGFNAEIKIGNALPMKNIPIGTVIHNVEIKPGKGGQIARSAGTYVQLISRENSYVTIRLRSGETRKLESKCRATIGEVGNSESMLRVLGKAGASRWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVSPWGLQTKGKKTRKNKRTEKFIIRHRHK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: METAS_SHEB8
Sequence: MPVRIPDHLPAAEVLESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHTSIDHMNTFYRDFEAVRHKNYDGLIITGAPLGQIDFEDVVYWDHIREIIDWSQEHVTSVLFLCWAAHAGLYHLYGLNRKILQQKRSGVFVHRRTSQHFPLLRGFDDEFFAPHSRFAEMDVEEIRQHPQLQLLAESDEAGAYLVLSRNNRNLFVMGHPEYQKSTLNEEYQRDLSQGLDPNVPQNYYRNDDPKADAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMTAMTPWESR
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_HAES1
Sequence: MQFSKMHGLGNDFVVVDAVTQNVYFPTEVIKRLADRNRGIGFDQLLVVEPPYDPDLDFHYRIFNADGSEVSQCGNGARCFARFVVLKGLTDKKEIAVSTAKGKMMLRVKDDDMVCVNMGEPIWEPNKIPFNANKFEKNYIIRTDIQTLLCGVVSMGNPHCVTQVEDIQHANIEILGPLLESHERFPERVNAGFMQIINRNHIKLRVYERGAGETQACGSGACAAVAVGIMQGVLDNNVQVDLPGGRLMIEWQGKGHPLYMTGEATHIYDGVIRL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTF3_CANCA
Sequence: IQSTSMDQGILTEDSMNSFIRTLIQAGIWKNKLPKQTARTKDGMQTTVKRTEAEADAMASKGFQPIVSVDAELLRQQRRFSSPRVLLSENAPLEPPPLYLTEEPLVQNRTSRRKREGKRHRGEYSVCDSESRWVTDKSSAVDIRGHQVTVLGEIRMGPS
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_METBF
Sequence: MFLELKAQATSILKDAIQKAGLEIEDSELYFETSSYADLASRAAFRLASLYRQNPKELATRIVSAVEIPDGSYIGKVSASGPYINFHASRRYMDKTVATVLEEKEKFGCGAPKDKILLEHTSANPNGPLHVGHIRNSIIGDTLARILRRAGYDVEVQYYVNDMGRQIAVVSWACERFELDLSRKSDSAIADVYIKANVELDKNPEYVKEIDALMEKVEAGDVKTIDSFYKAVSLAISGIKETLLRLNVVHDKFVSESTFLKSGAVHDIVERIKATGRTKTDKGALVVDLSDYGFKKTLVIQRSNGTSLYTTRDLAYHEWKAGQADRIIDIFGADHKLISGQLRATLNSIGVKEPEVVIFEFVSLPEGSMSTRRGQFISADELFDRVTEAALEQVETRRPETSEEFKKQVAEMVGIGAVRYDIVRVSPEKSTVFNWKEALDFEKQGAPYIQYSHARACSILEKAKEEAAWNSSAEIDPSLLVEDTEIDLIKKMASFDRVIDLAARELKPHVLAIYARELADAFNQFYRFVPVIAAEDEKVRASRLALVNCARIVLANSLDTLGIAAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_COXB1
Sequence: MAEKLHISVLCGGQSTEHEISIQSAKNIVNTLDAAKYLISLIFIDHVGRWYLIDQPEMFLAHSPDHLVKEGSARPITIAFGDAAKPWQSLNGDGRRYSADCVFPMVHGTQGEDGALQGLLELLNLPYVGANVQSSAVCMEKDLTKTVLRAGGIPVVDWHTLSPRDATEGVYQRLLDRWGTSELFVKAVSLGSSVATLPVKTETEFTKAVKEVFRYDDRLMVEPRIRGREIECAVLGNGAPKASLPGEIIPHHDYYSYDAKYLDPNGATTTTSVDLSESVTKQIQQIAIDAFKMVHCSGMARVDFFVTPNNKVLVNEINTIPGFTNISMYPKMWEASGLPCPNLLDQLIELAIDRHQEQQKLIRCYEVKARSL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBPC_ECOLI
Sequence: MPRLLTKRGCWITLAAAPFLLFLAAWGADKLWPLPLHEVNPARVVVAQDGTPLWRFADADGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSRLRPDRWPERAEAARNKVLERMAVQGVWSREQVKESREEPIWLAPRQMPQLAPLFSRMMLGKSKSDKITTTLDAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRFGHVDMVNSIRSPGSVLKPFVYGLALDEGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEALVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILGGAGAKLEDMAAAYTAFARHGKAGKLRLQPDDPLLERPLMSSGAAWIIRRIMADEAQPLPDSALPRVAPLAWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNILLSRSANLPEDPRPNSVTRGVICWPGGQSLPEGDGNCRRRLATWLLDGSQPPTLLLPEQEGINGIRFPIWLDENGKRVAADCPQARQEMINVWPLPLEPWLPASERRAVRLPPASTSCPPYGHDAQLPLQLTGVRDGAIIKRLPGAAEATLPLQSSGGAGERWWFLNGEPLTERGRNVTLHLTDKGDYQLLVMDDVGQIATVKFVMQ
What is the function of this protein?
Cell wall formation.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional.
What are the official names of this protein?
Penicillin-binding protein 1C, PBP-1c, PBP1c.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: Y983_CAMJE
Sequence: MKKGIFLSIGIAVLFSACGNSIDEKTVKKYENQLNQTVKQEIASLSQDSGIKIEFSDFKCNADGDFIACLSPNFKTLTKDNNDEYQELFQAKNIKIRSNEIYKGKANASISIKEYYNDLFKNQKSIQSNLVFEDFKLGEKVVSDINASLFQQDPKISSFINKLSSDSYTLSFDNSINKQENNYLDNLDIKFYNAKLNFNTNLNINLKEDLLNYLDSKGIKFNTQTLVMDKQAINELLNIANYEQASDFSNTIQKYIILNNFKIDSTLKTEGVFSSYIATAKENLQTLKAQSQNEEQALIFDKALAILNNITQNDDYKLNLDLKFKNIPVSDYSTQGIDSIEKLSINNQDATEALKIILPFIMFSMLMGGASF
What are the official names of this protein?
Uncharacterized lipoprotein Cj0983.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SECB_SHEB5
Sequence: MAEVANNEQQAPQFNIQRVYTKDVSFETPNSPAVFQKEWNPEVKLDLDTRSAKLADDVYEVVLSLTVTAQNGGDTAFLCEVQQAGIFSITGLTEPQLAHSLGAYCPNFLFPYARETVGSLVGRGTFPQLNLAPVNFDALFAQYVQQRQAAATAPAAEEANA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_HAEIG
Sequence: MKIGILALQGAFAEHAQMLEKLGIESVELRNLKNFQQHYSDLSGLILPGGESTAIGKLLRELYMLEPIKQAISSGFPVFGTCAGLILLAKEITSQKESHFGTMDIVVERNAYGRQLGSFYTEADCKGVGKIPMTFIRGPIISSVGKKVNILATVNNKIVAAQEKNMLVTSFHPELTNNLSLHKYFIDICKVA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DCD_ERYLH
Sequence: MAILSDKWIREAAQTRGMIEPFEEAQRRDGCISYGLSSFGYDARVAPEFKIFTNVNSAVVDPKDFDGDSLVDRETEVCIIPPNSFALARTVEYFRIPEDVLVICLGKSTYARCGIIVNVTPLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFLFLQGNERPEVTYADRAGKYMGQRGVTLPRL
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PNP_CITBB
Sequence: MVHTVQAECCGKTITIETGKIAKQASGAVMIKSGDTMVLVTAVAMKSAKEGQGFFPLTVNYQEKAYAGGRIPGSFFKREGRPSDNETLTCRLIDRPIRPLFPENFLNDTQIMATVVSADKDNDPGILSMIGASAALMVSDVPFAGPIAGVKVGRVDGQFIANPTAEQEEKSDLEIVIAASQDAILMVEGSACEVSEDDLLEAIFFGHKAVQPVLAAQLELAKKVGTSKREIPAPVVNEALKARVSALAKEGMKQAVRIKTKVERHLAIDAIADETVAALSAEFEGSEKEIKGFIEDLEYDLVREHIIKDGQRIDGRDTKTIRAISTEVSLLPRAHGSALFTRGETQSIVAATLGTSVDEQRIDSLYGDSRKKFMLHYNFPPYSVGETSFRLAPGRREIGHGMLAERALQQVLPKHDDFPYTIRIVSDITESNGSSSMATVCGGSLSMMDAGIPIKAPVAGIAMGLIKEGDDFAILSDILGDEDHLGDMDFKVAGTAEGVTALQMDIKIGGVTREIMSAALAQAKAGRIHILGEMAKTIGASRGDLSAFAPRITTIWVKVDKIRDVIGSGGKNIRSVTEATGVSIDIDDTGKINIASTNKEACDLAIKMIRNLTAEAEEGKLYMGTVKKIMEFGAFVEIFPGTDGLVHVSELDTERVKNVSDILKEGDKVLVKCIGIDKQGKIKLSRKEALGLTFTE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSPH_PROJR
Sequence: MVLVRVLANLLMLQLSYAQKSSELIIGGDECNINEHRFLVALYTFRSRRFHCSGTLINEEWVLSAARCDRKNIRIQLGMHSTNVINEDVQTRVPKEKFFCLSSKTYTKWNKDIMLIRLKKPVNNSTHIAPVSLPSNPPSLGSVCRVMGWGTISATKETHPDVPYCANINILDYSVCRAAYARLPATSRTLCAGILEGGKDSCLTDSGGPLICNGQFQGIVSWGGHPCGQPRKPGLYTKVFDHLDWIKSIIAGNKDATCPP
What is the function of this protein?
Snake venom serine protease homolog (PubMed:18590752).  May act in the hemostasis system of the prey (Probable).
What are the official names of this protein?
Snake venom serine protease homolog, TjsvSPH, Serine proteinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KYNB_CUPTR
Sequence: MTAPNPDPRRLWDISPPLSPATPVWPGDTPFQQQPAWQIDAQCPVNVGRITLSPHTGAHADAPLHYAADGAPIGAVPLAPYLGRCRVIHCIGAAPLVQPHHVEHALDALPPRVLLRTYRQAPLAQWDPDFCAVSPDTIALLAAHGVQLVGIDTPSLDPQDSKTMDAHNAVRRHGLAILEGIVLDQVDAGDYELIALPLRFAALDASPVRAVLRSLD
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: PPK1_BRASB
Sequence: MDTEQAIEIQEKDPVSSPPAEIASSPERFINRELSWLHFNRRVLEESVNPRHPALERVRFLSISANNLDEFFMVRVAGIRAQVREGIAERSPDGLTPLEQLKVINESVSQLAIDQQAIWRDLRKFLAELGIVLVDGQDVTKSERAWIEDHFLASIFPLLTPLAIDPAHPFPFIPSLGFTVALQLMRTSDGRPMNALIRMPGKIDRFIRFPGSKDGVIRLITLEQATSLFIGRLFPGYTVKGQGAFRIIRDSEIEIEEEAEDLVRLFETALKRRRRGSVIRLEIEANMPEELRAFVQDALSTTDDEVFVVDGVLAMNELSQLTRVDRPDLEFAPYVPRHPERVRDHGGDIFAAIRQKDLIVHHPYESFDVVVQFLQQAARDPDVVAIKQTLYRTSNNSPIVRALAEAAEAGKSVTALVELKARFDEEANIRWARDLERAGVQVVYGFLQLKTHAKLSMVVRREGGGLTTYVHTGTGNYHPVTARIYTDLSYFTSDPVIGRDVTRVFNYITGYAEPIDIEKMAVSPLTLRKRMIEHIHGETSFARQGKPAVIWMKMNSLVDPDIIDALYEASQAGVSIDLIVRGICCLRPGLPGLSENIRVKSVIGRFLEHGRIYCFGMGQGLPSAKAAVYISSADMMPRNLDRRVEVLCPLQNPTVHQQVLEQIMVANLKDTEQSWQLLPDGSSTRMKAAKGEEPFNLHNYFMTNPSLSGRGKSLKESSPRRLTRRNERNPS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: RS4_THESM
Sequence: MGDPKRQRKRYETPSHPWIKERLDRERVLVQKYALKNKKELWKHETQLKNFRRRARRLLAARGKQAEIERAQLLQRLARLGILPEGAHLDDVLSLTIDDILERRLQTLVFKKGLARTIKQARQLIVHGHIEVNGQIIRSPSYLVLKEEEDGITYGRASPFANSQHPERMVIEEVQKGEAQ
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RPOA_POPTR
Sequence: MVREKVRISTRTLQWKCVESRADSKRLYYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRAKSKKIPHEFSTITGIQESIHEILMNLKEIVLRSNLYGTHDASICVKGPGCVTAQDIILPPSVEIIDNTQHIASLREPIDLHIGLEIERNRGYCMKPPKNFQDGSYSIDAVFMPVRNANHSVHSYGNGNEKQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHAEEENFHLEKNQHKITLPLFAFHDRLAKLRKNQKEIALKSIFIDQLELAPKIYNCLKRSNIHTLWDLLKNSQEDLMKIEHFRIEDVKHIFGILKIEKHFTINLPKNKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HETR_NOSS1
Sequence: MSNDIDLIKRLGPSAMDQIMLYLAFSAMRTSGHRHGAFLDAAATAAKCAIYMTYLEQGQNLRMTGHLHHLEPKRVKIIVEEVRQALMEGKLLKTLGSQEPRYLIQFPYVWMEQYPWIPGRSRIPGTSLTSEEKRQIEHKLPSNLPDAQLVTSFEFLELIEFLHKRSQEDLPPEHRMELSEALAEHIKRRLLYSGTVTRIDSPWGMPFYALTRPFYAPADDQERTYIMVEDTARYFRMMKDWAEKRPNAMRALEELDVPPERWDEAMQELDEIIRTWADKYHQVGGIPMILQMVFGRKED
What is the function of this protein?
Controls heterocyst differentiation; increased expression leads to more heterocysts than usual (PubMed:1840555).  Has protease activity (PubMed:9560210).  Binds the promoter regions of hetR, hepA and patS and is required for their expression.  Dimerization is required for DNA-binding, DNA-binding is inhibited by the PatS6 peptide (PubMed:15051891).  In Nostoc filaments, approximately every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation (PubMed:8412673, PubMed:10692362, PubMed:15051891).
What are the official names of this protein?
DNA-binding transcriptional activator HetR, Heterocyst differentiation control protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S48 family.
Protein: HC2B_CHLTH
Sequence: MLGVQKKRSTRKTAARKTVVRKPAAKKTAAKKAPVRKVAAKKTVARKTVAKKTVAARKPVAKKATAKKAPVRKVAAKKTVARKTVAKKTVAARKPVAKRVASTKKSSVAVKAGVCMKKHKHTAACGRVAASGVKVCASAAKRKTNPNRSRTAHSWRQQLMKLVAR
What is the function of this protein?
Might have a role in establishing the nucleoid structure of elementary bodies.
What are the official names of this protein?
Histone H1-like protein HC2, HC2 nucleoprotein.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family. HCT subfamily.
Protein: SIAT2_XENTR
Sequence: MKPNLKQWKQFMLFGICAWGLLFLVIFVYFTDSNSVEPVPSAFSYVESKKHFPLQGKQRAIMGAHQDQLFSYAIDDQDLLKEGILDSFIVGPGSMKKMAGADNYFESEQEFIMSKKTQKSTSNNHEDDDDEIYLHKNIDSVSGKKAPAYGKRYYHDTQRQHKKIRRNMQRKKQHMIEDSYDWNGFSSSMSKSFLQKLWKGNVSSKMLTPRLQKARREYLRANKLGVNFNGKQNSRKLNPQELLCVLKDRAQVKTLDGKDAPFSSLGWEKYFPKIALNKLYPHGFSTCAVVSSAGAILNSSLGAEIDSHDAVLRFNSAPTRNYEKDVGNKTTLRIINSQILTNPNHHFTDSSLYKDVTLIAWDPSPYYADLHMWYHKPDYNLFPPYEKHRKRNPDQPFYILHPKFTWELWKIIQENSNEKIQPNPPSSGFIGILIMMSMCRTVHVYEYIPSYRQTDLCHYHEQYYDAACTLGAYHPLLYEKMLIQRINQGTEDNLLRKGKVILPGFSSIHCPIKDHIT
What is the function of this protein?
Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.
What are the official names of this protein?
Beta-galactoside alpha-2,6-sialyltransferase 2, Alpha 2,6-ST 2, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2, ST6Gal II, ST6GalII, Sialyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: DIT21_ARATH
Sequence: MESFALHSLSTTATSTLLSHHHHHHPSRLSLLRRTSSRSPPSTISLRSLSVQPLSFPLLKPIPRFSTRIAAAPQDNAPPPPPPSPSPSPSPQGAKLIPLILSISVGLILRFAVPVPEGVTPQGWQLLSIFLSTIAGLVLSPLPVGAWAFIGLTASIVTKTLSFSAAFSAFTSEVIWLIVISFFFARGFVKTGLGDRIATYFVKWLGKSTLGLSYGLTLSEALIAPAMPSTTARAGGIFLPIIKSLSLSAGSKPNDSSSRKLGSYLIQSQFQCAGNSSALFLTAAAQNLLCLKLAEELGVVISNPWVSWFKAASLPAIISLLCTPLILYKLYPPETKDTPEAPGIAATKLKQMGPVTKNEWIMVGTMLLAVTLWICGETLGIPSVVAAMIGLSILLVLGVLNWDDCLSEKSAWDTLAWFAVLVGMAGQLTNLGVVTWMSDCVAKVLQSLSLSWPAAFGLLQAAYFFIHYLFASQTGHVGALFSAFLAMHIAAGVPGILAALALAYNTNLFGALTHYSSGQAAVYYGAGYVDLPDVFKIGFVMATINAIIWGVVGTFWWKFLGLY
What is the function of this protein?
Glutamate/malate translocator involved with DIT1 in primary ammonia assimilation and in the re-assimilation of ammonia generated by the photorespiratory pathway.  Exports the end product of ammonia assimilation, glutamate, from plastids to the cytosol.  The precursor for ammonia assimilation, 2-oxoglutarate, is imported from the cytosol by DIT1.
What are the official names of this protein?
Dicarboxylate transporter 2.1, chloroplastic, AtpDCT1, Glutamate/malate translocator.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: GREA_BORBU
Sequence: MSNVTTIEKLDSILQEDKWTRIVVNNYSLAKIKELDDLINNIIDEGLTEDVLDICGRHLKDVKKSIAGLYISGMLIYSRRPLNDMNLLAVIDLFSQNLKWALVEHICNEMLLISENKHALYTLAKIYAQNNENDKLPGIWTRIVEADIDDTVFVRQLATYYETIDLQKSIFYFRKAIYRFIDKKQMSGIREVWAKLIHYVSDDFDSFLLILQKIEKDLGFKKAIVLYEDLFDHYSLTDNVDETIEILKGILKLDNKNHKARENLVKFLRERYKDVKNIEDYLVKSDIENLDKNFVDVYLDFEKYLFFAKGNFVYHQTWSVGIVRDVNDNGITVDFVSKRGHFIGFDMAMSALSPLSREDIRVLKAVTPKEELADRVKKDIEWAIKVIIKSYKAIDLKGIKKELVPSLMTQSSWNSWSLKAKQILKDNPHFVMDSGKLDCYIYNERSSNLNEKMYDKFKIEKDFYKRYEIFINYCNVKGIVKDLHIEEEMLNYFLIYVNNFTKVDHHVVSSYVILKSLGNFSEELSSKVNIEKDVNLESLLKEYPKGIVDLFDSILNAEIKKELVVLIKEELSNWILYYKELFPHSVNKRLVESLYKEDPREVEKLFNYVIKNYKIYKDAYIWILKHCKAYSIELSYSDSDLLSNLIKILTDSVIKINNKNNSVASKRIYKMVINLLVKDGYLKSVLEVVRDEELAKRVYMTCFYVKDFPPKDLLEIKSIIRQLFDSVEFEDEKMQLAGERMEIGFLTILSSLNKKQKELKYLKEVEIPENSKEIGKARELGDLKENAEYHSAKEKQQFLTKRLNSLMLEIENAKVIDTKDLQSSVVGFGTKVVILNEVTGKDESYLILGPWESNPDEGIISYKSPFGENLLDSREGDSLNFVINNTNFKYFVKKIEPIKFS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides (By similarity).
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: VPK2_VACCP
Sequence: MGVANDSSPEYQWMSPHLNYFKNFNKETLLKIEENDYINSSFFQQKDKRFYPINDDFYHISTGGYGIVFKIDNYVVKFVLEAIKLYSPMEIMAELTVPKFLYNNLKGDEKKLIVCVWAMGLNYKLTFLHTLYKRVLHMLLLLIQTMDGQELSLRYSSKVFLKAFNERKDSIKFVKLLSHFYPAVINSNINVINYFNRMFHFFEHEKGTNYEYERGNIIIFPLTLYSADKVDTELAIKLGFKSLVQYIKFIFLQMALLYIKIYELPCCDNFLHADLKPDNILLFDSNEPIIIHLDKKFVFNERIKSALNDFDFSQVAGIINKKIKNNFKVEHNWYYDFHFFVHTLLKTYPEIEKDIEFSTALEEFIMCTKTDCDKYRLKVSILHPISFLEKFIMRDIFSDWINGGN
What is the function of this protein?
Essential serine-protein kinase involved in the early stage of virion morphogenesis.
What are the official names of this protein?
Serine/threonine-protein kinase 2, Vaccinia protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.
Protein: RF3_NITEU
Sequence: MTIDHEVKRRRTFAIISHPDAGKTTLTEKLLLFAGAIHIAGSVKARKASRHATSDWMEIEKQRGISVASSVMQMEYRDCVINLLDTPGHQDFSEDTYRVLTAVDAALMVIDAANGVESQTLRLLQVCRARNTPIITFVNKLDREVREPLDLIDEIERTLGMDVIPFTWPVGSGKRFHGVYDLRHKLMRVFRAGMDRVEQEETAIITNLEDPAISERFGANLEQARQEIELITGAAPEFDQTAFLAGQQTPVFFGSAINNFGVQEVLDTLVELAPPPGSRKAIQREIQPAEKKFSGVVFKIQANMNPAHRDRIAFVRICSGEFRRGMNLKVVRSGKDVRTSTVVSFLSQRRELLETAYAGDIIGIPNHGTLQLADTLTEGDHLQFTGLPFFAPEIFQTVEIADPLRSKQLKLGLAQLGEEGAIQVFRPHIGSMLLLGAVGVLQFEVVTHRLKHEYGVEARIAPAKYQLARWVTAETPQELQRFIDANAHRIAYDAVNAPTFLASFSAEISVAEENWPGIRFHKMREHAGLMFQTAG
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.