PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_SHEPA
Sequence: MKHIRNFSIIAHIDHGKSTLSDRLIQECGGLTDREMAAQVLDSMDIERERGITIKAQSVTLDYLANDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTALEMDMDVVPVLNKIDLPQADPDRVAEEIEDIVGIEATDAVRCSAKTGIGIKDVLEVIVEQIPPPEGDPEGPLQALIIDSWFDSYLGVVSLVRIKNGILKKGDKFKVMSTGQNYNADRVGIFTPKQTDTTELKTGEVGFVIAGIKEIHGAPVGDTLTHSKHGAETPLAGFKKVKPQVYAGLFPISTDDYENFRDALNKLSLNDASLFFEPETSSALGFGFRIGFLGLLHMEIIQERLEREYNLELITTAPTVVYEIVQTNGETIYVDNPSDLPAVNNIAEMREPIVETNILVPKEYLGNVITLCIEKRGVQTNLVYHGNQVALTYELPMAEVVMDFFDRLKSTSRGYASLEYNFIRFEPADMVRLDILINGDRVDALAMIIHKGLIRSKGLALVNKMKELIPRQMFDIAVQAAVGSQIIARSSIKAMRKDVTAKCYGGDVSRKKKLLNKQKEGKKRMKQVGNVEVPQEAFLAVLKLND
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AB48G_ORYSJ
Sequence: MAAAPSASGRRSMSWGSSISQSFRQAEADDPFGRAASQQGHDDDEENLRWAALEKLPTYDRMRRGVIRTALLHHDGGGDGGGAAAAAKDGRMELVDIQKLAAGNLGRALLDRVFQDDSERFLRRLRDRIDMVGIELPTIEVRYEQLSIQAEVFVGSRALPTLTNAATNVLQGLIGRFGSSNKRTINILQDVSGIIKPSRMTLLLGPPSSGKSTLMRALTGKLDKNLKVSGDITYCGHTFSEFYPERTSAYVSQYDLHNAEMTVRETLDFSGRCLGIGARYDMLAELARRERNAGIKPDPEIDAFMKATAVQGHKTNITTDVTLKALGLDICADIIIGDEMIRGISGGQKKRVTTGEMLTGPARALFMDEISTGLDSSSTFEIVKYIGHLVHVMNETVMISLLQPPPETYNLFDDIILLSEGYIVYHGPRENILEFFENAGFRCPERKGIADFLQEVTSKKDQQQYWYHDQERYRYVSVPEFAQRFKSFHVGQKMQKEMQIPYDKSSTHPAALTTTKYGLSSWESLRAVMSREWLLMKRNSFIYIFKVTQLIILAFMSMTVFLRTKMPSGTISDGTKFLGALTFSLITILFNGFAELQLTIKKLPVFYKHRDFLFFPAWTFGVANILLKVPVSLVEAAVWVVLTYYVMGFAPSAGRFFRQFIAFFVTHQMAMAMFRFLGAILKTMVVANTFGMFVLLIVFIFGGFLISRNDIKPWWIWGYWASPMMYSQQAISINEFLASRWAIPNTDATIDEPTVGKAILKSKGLITSDGGFWISIGALIGFLVVFNILYILALTYLSPGGSSNTIVSDEDSEDKTDMKTRNEQQMSQIVHNNGASNTSATSSIPMSGSRSTNQQSRSQIVLPFQPLSLCFNHVNYYVDMPTEMKEQGFTESRLQLLSDISGVFRPGVLTALVGVSGAGKTTLMDVLAGRKTSGVIEGDITLSGYPKKQETFARISGYCEQTDIHSPNVTVYESILYSAWLRLSSDVDTNTRKMFVDEVMSLVELDVLRNALVGLPGVSGLSTEQRKRLTIAVELVANPSVIFMDEPTSGLDARAAAIVMRTVRNTVNTGRTVVCTIHQPSIDIFESFDELLLLKRGGQVIYAGELGRHSHKLVEYFEAVPGVPKITEGYNPATWMLEVTSPIAEARLNVNFAEIYANSELYRKNQELIKELSTPPPGYQDLSFPTKYSQNFYSQCIANFWKQYRSYWKNPPYNAMRYLMTLLNGLVFGTVFWQKGTKISSQQDLFNLLGATYAATFFLGAANCITVQPVVSIERTVFYRERAAGMYSSLSYAFAQACVEVIYNILQGILYTIIIYAMIGYDWKADKFFYFMFFIVASFNYFTLFGMMLVACTPSAMLANILISFVLPLWNLFAGFLVVRPLIPIWWRWYYWANPVSWTIYGVVASQFGKNGDVLSVPGGSPTVVKQFLEDNLGMRHSFLGYVVLTHFGYIIVFFFIFGYAIKYFNFQKR
What is the function of this protein?
May be a general defense protein.
What are the official names of this protein?
ABC transporter G family member 48, OsABCG48, Pleiotropic drug resistance protein 3, OsPDR3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYP_BRASO
Sequence: MRLSRFFLPILKENPKEAEIVSHRLMLRAGMLRQEAAGIYAWLPLGFKVLKKIEQIVREEQNRAGALELLMPTLQLADLWRESGRYDAYGPEMLRISDRHKRELLYGPTNEEMITEIFRAYVKSYRNLPLNLYHIQWKFRDEQRPRFGVMRGREFLMKDAYSFDLDEAGARRAYNKMFVAYLRTFARMGLKGIPMRAETGPIGGDLSHEFIVLAETGESGVYCDRNVLDLPIPSASVDYDGDLTPIIKEWTSLYAATEDVHDGARFEAEVPAERRVHTRGIEVGQIFYFGTKYSEPMKALVAGPDGAEVTIHGGSYGVGVSRLAGAIIEACHDDAGIKWPEEVAPFRAVILNLKQGGSDTDAACEQLYRDLLAKGVDVLYDDTEQRAGGKFATADLIGIPWQIMVGPKSLAEGKVEVKTRSDGAREMMSPADIVARLGAGTAAS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WZA_SALTY
Sequence: MMKSKMKLMPLLASLSLISGCTVLPGSNMSTMGKDVIKQQDADFDLDRMVNVYPLTPRLVEQLRPRPNVAQPNMSLDQEIASYQYRVGPGDVLNVTVWDHPELTTPAGQYRSSSDTGNWVQPDGTMFYPYIGKVSVVGKTLSEIRSDITGRLAKYIADPQVDVNIAAFRSQKAYISGQVNKSGQQAITNVPLTVLDAINAAGGLTDMADWRNVVLTHNGKEQRISLQALMQNGDLSQNRLLYPGDILYVPRNDDLKVFVMGEVKKQSTLKMDFSGMTLTEALGNAEGIDLTTSNASGIFVIRPLKGEGGRGGKIANIYQLDMSDATSLVMATEFRLQPYDVVYVTTAPVARWNRLINQLLPTISGVRYMTDTASDIHSW
What is the function of this protein?
Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium.
What are the official names of this protein?
Putative polysaccharide export protein wza.
What is the protein family that this protein belongs to?
Belongs to the BexD/CtrA/VexA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: ARCA_STRP1
Sequence: MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD, Streptococcal acid glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_ECOL5
Sequence: MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLREAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAATPAPTKEEVLLTEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MMP1_LITCT
Sequence: MLSGLWSSILALLGVFLQSVGEFRAETQEQDVEIVQKYLKNYYNSDKRNSGLVVEILKQFFGLKVTGKPDAETLVMKQSTCGVPDVGEYVLTPGNPRWENTHLTYRIENYTPDLVSPLTFTKVSEGQADIMISFVRGDHRDKYPFDGPGGNLAHASQPGPGIGGDAHFDEYERWTKNFQDYNLYRVAAHELGHSLGLSHSTDIGALMYPTYLRGDVQLSQDDIDGPSGNPVQPRGPQTPQVCDSKLTFDAITTVRGELMFFKMRTNRFYPEVELGLQAAYEMADRDEVRFFKGNKYWAVSGQDVLYGYPKDIHSSFGFPTGVAHECWSYDEYKQSMDTGYADEFPGDAVFQKFFHGTRQYQFDLKTKRILTLQKANSWFNCRKN
What is the function of this protein?
Cleaves collagens of types I, II, and III at one site in the helical domain.  Also cleaves collagens of types VII and X.
What are the official names of this protein?
Interstitial collagenase, Matrix metalloproteinase-1, MMP-1, TC1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL11_CHLTE
Sequence: MAKKITGFIKLQIPAGGANPAPPVGPALGQKGVNIMEFCKQFNAKTQSEAGMIIPVVITVYSDKSFTFVTKTPPAAVLLLKEAKLQKGSGEPNRNKVGTVTMDQVRKIAELKRPDLNSIDLEGATQMVIGTARSMGIVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PTGDS_HUMAN
Sequence: MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ
What is the function of this protein?
Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation (PubMed:20667974).  Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes.  Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter.  Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier.  It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system (PubMed:20667974, PubMed:9475419).  Involved in PLA2G3-dependent maturation of mast cells.  PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity).
What are the official names of this protein?
Prostaglandin-H2 D-isomerase, Beta-trace protein, Cerebrin-28, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, L-PGDS, Prostaglandin-D2 synthase, PGD2 synthase, PGDS, PGDS2.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum. Nucleus membrane. Golgi apparatus. Cytoplasm, perinuclear region. Secreted. Note=Detected on rough endoplasmic reticulum of arachnoid and menigioma cells. Localized to the nuclear envelope, Golgi apparatus, secretory vesicles and spherical cytoplasmic structures in arachnoid trabecular cells, and to circular cytoplasmic structures in meningeal macrophages and perivascular microglial cells. In oligodendrocytes, localized to the rough endoplasmic reticulum and nuclear envelope. In retinal pigment epithelial cells, localized to distinct cytoplasmic domains including the perinuclear region. Also secreted.
Protein: RS17_CHLTR
Sequence: MASDVRGRRKTKIGVVVSSKMEKTVVVRVERVYSHPQYAKVVRDSSKYYAHNELDVKEGDTVRIQETRPLSKTKRWRVVGRVN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS21_CAMC5
Sequence: MPGIKVHPNESFDEAYRKFKKQVDRNLIVTEVRARRFFEPMTEIRKKQKISARKKMLKRLYMLRRYESRL
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RPOE_STRA3
Sequence: MELEVFAGQEKSELSMIEVARAILEQRGRDNEMYFSDLVNDIQTYLGKSDSAIRESLPFFYSDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDGAPKRKKKRVNAFMDGDEDAIDYNDDDPEDEDFTEETPSLEYDEENPDDEKSEVESYDSEINEIIPDEDLDEDVEINEEDDEEEEEEEEV
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: CREM_CANLF
Sequence: MSKCSRKKYIKTNLRQMTMDTMESQQDGSVTDSVAENESAHMQNQTGQNSIPTLTQVSVAGSGTGRGSPAVTLVQLPSGQTVHVQGIIQTPQPSVIQSPQIQTVQVATIAETDESAESEGVIDSHKRREILSRRPSYRKILNELSSDVPGVPKIEEEKSEEEGTPPNIATMAVPTSIYQTSTGQYIAIAQGGTIQISNPGSDGVQGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFVPGSQVVVQDEETELAPSHMAAATGDMPTYQIRAPTTALPQGVVMAASPGSLHSPQQLAEEATRKRELRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKAE
What is the function of this protein?
Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters.  Isoforms are either transcriptional activators or repressors.  Isoform Tau is a transcriptional activator.  Plays a role in spermatogenesis and is involved in spermatid maturation (By similarity).
What are the official names of this protein?
cAMP-responsive element modulator.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPT7_YEAST
Sequence: MTERIPIKNYQRTNAKALLKLTEKLFNKNFFDLYLTSQQLVVLEYLLSISSEEDKLKAWDYFLKGNIALNVEKSFPLTQEEEHHGAVSPAVDTRSDDVSSQTIKDNNNTNTNTSISNENHVENEIEDKGDNAIANEDNFVNNDESDNVEEDLFKLDLEDLKQQISGTRFIGNLSLKIRYVLWQCAIDYIYCDRNEFGDENDTEYTLLDVEEKEEEEIGKNEKPQNKEGISKFAEDEDYDDEDENYDEDSTDVKNVDDPPKNLDSISSSNIEIDDERRLVLNISISKETLSKLKTNNVEEIMGNWNKIYHSFEYDKETMIKRLKLEESDKMIEKGKKKRSRSDLEAATDEQDRENTNDEPDTNQKLPTPEGSTFSDTGNKRPKQSNLDLTVNLGIENLSLKHLLSSIQQKKSQLGISDYELKHLIMDVRKNRSKWTSDERIGQEELYEACEKVVLELRNYTEHSTPFLNKVSKREAPNYHQIIKKSMDLNTVLKKLKSFQYDSKQEFVDDIMLIWKNCLTYNSDPSHFLRGHAIAMQKKSLQLIRMIPNITIRNRADLEKEIEDMEKDKDYELDEEEEVAGSGRKGLNMGAHMLAKENGKVSEKDSSKTVKDEAPTNDDKLTSVIPEGEKEKDKTASSTVTVHENVNKNEIKENGKNEEQDMVEESSKTEDSSKDADAAKKDTEDGLQDKTAENKEAGENNEEEEDDDDEDEDEDMVDSQSYLLEKDDDRDDLEISVWKTVTAKVRAEICLKRTEYFKNGKLNSDSEAFLKNPQRMKRFDQLFLEYKEQKALESYRQKIEQNSIMKNGFGTVLKQEDDDQLQFHNDHSLNGNEAFEKQPNDIELDDTRFLQEYDISNAIPDIVYEGVNTKTLDKMEDASVDRMLQNGINKQSRFLANKDLGLTPKMNQNITLIQQIRHICHKISLIRMLQSPLSAQNSRSNPNAFLNNHIYNYTIIDDSLDIDPVSQLPTHDYKNNRELIWKFMHKNISKVAMANGFETAHPSAINMLTEIAGDYLSNLIKTLKLHHETNSLNRGTNVEMLQTTLLENGINRPDDLFSYVESEFGKKTKKLQDIKQKLESFLRALLRPTLQELSERNFEDESQSFFTGDFASELTGEDFFGFRELGLEKEFGVLSSSVPLQLLTTQFQTVDGETKVQAKKIQPEESDSIVYKKITKGMLDAGSFWNTLLPLLQKDYERSKAYIAKQSKSSANDKTSMTSTEDNSFALLEEDQFVSKKTATKARLPPTGKISTTYKKKPIASAFILPEEDLENDVKADPTTTVNAKVGAENDGDSSLFLRTPQPLDPLDMDDAFDDTNMGSNSSFSLSLPRLNQ
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK.  SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8).  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  SALSA an altered form of SAGA, may be involved in positive transcriptional regulation.  SLIK is proposed to have partly overlapping functions with SAGA.  It preferentially acetylates methylated histone H3, at least after activation at the GAL1-10 locus.  SPT7 is transcriptional activator of TY elements and other genes.
What are the official names of this protein?
Transcriptional activator SPT7.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3860_BREBN
Sequence: MFEVRRLQINYKTLEEFQKFREFGLEELSMKEDLEANIVENDSESPFYGIYDNDLLVARMSLYKIDGKYDRYFQPAQDYYELWKLEVLPDYRSKDYGTALVNHAKSFGAPIKTNSRCRADDFWLKMGFTPVKYNLMRDRGENPYVWLPESVELQD
What are the official names of this protein?
Uncharacterized N-acetyltransferase BBR47_38600.
Protein: HXK2_DROME
Sequence: MRKSTRLLTHSLFGPVFKILFHNKTVCGGCNRKMPSLVNTEIEAAVKGFLIDQEKMTEVVERMTKEIKMGLAKDTHARAVIKCFVSHVQDLPTGKERGKYLALDLGGSNFRVLLVNLISNSDVETMSKGYNFPQTLMSGSGKALFDFLAECLSEFCHSHGLENESLALGFTFSFPLQQQGLSKGILVAWTKGFSCEGVVGKNVVSLLQEAIDRRGDLKINTVAILNDTVGTLMSCAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQTSPKPSMIINCEWGAFGDNGVLEFVRTSYDKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITDMIAKGFMFHGIISEKIQERWSFKTAYISDVESDAPGEYRNCNKVLSELGILGCQEPDKEALRYICEAVSSRSAKLCACGLVTIINKMNINEVAIGIDGSVYRFHPKYHDMLQYHMKKLLKPGVKFELVVSEDGSGRGAALVAATAVQAKSKL
What is the function of this protein?
Catalyzes the phosphorylation of various hexoses to hexose 6-phosphate.
What are the official names of this protein?
Hexokinase type 2.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
Protein: SIRT2_DROME
Sequence: MDKVRRFFANTLHLGGSSDAKEEVKVEKVIPDLSFDGFAEHWRVHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAPFFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCIKCRKEYDMDWMKAEIFADRLPKCQKCQGVVKPDIVFFGENLPKRFYSSPEEDFQDCDLLIIMGTSLEVQPFASLVWRPGPRCIRLLINRDAVGQASCVLFMDPNTRSLLFDKPNNTRDVAFLGDCDAGVMALAKALGWDQELQQLITSERKKLSGSQNSEELQQGKEKPQSDPDKMTSGDRDKKDASL
What is the function of this protein?
NAD-dependent protein deacetylase (By similarity).  May be involved in the regulation of life span.
What are the official names of this protein?
NAD-dependent protein deacetylase Sirt2, Regulatory protein SIR2 homolog, SIR2-related protein.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
Protein: GLR26_ARATH
Sequence: MSLFNHLLSRALPLWLLFFINFLVLLGKSQQEVLQVQVGIVLDTNATLAALSLRAINMSLSEFYNTHNGFKTRIVLNIRDSKRTVVGAAASALYLIKKREVVAIIGPGNSMQAPFLINLGNQSQVPIISFSASSPVLDSLRSPYFIRATHDDSSQVHAISAIIESFRWREVVPIYADNEFGEGILPYLVDAFQEINVRIRYRSAISVHSTDDLVKKELYKLMTMPTRVFIVHMLPDLGSRLFSIAKEIGMMTKGYVWIVTNGIADQMSVMGESSLENMHGVLGVKTYFSRSKELMYLETRWRKRFGGEELNNFECWGYDTATALAMSIEEISSNVNMSFSQTKRNTSRDDTGTDLDDLSFALSGPKLLQALATVSFKGVAGRFQLKNGKLEATTFKIVNIEESGERTVGFWKSKVGLVKSLRVNQTGIKISHSSHRLRPIIWPGDTIFVPKGWEFPTNAKKLRIAVPKKDGFNNFVEVTKDANTNAPTITGFCIDVFDTAMRQMPYAVPYEYIPFETPDGKPRGSYDEMVYHVFLGEFDGAVGDTTILANRSTYVDFALPYSETGIVVVVPVKDEREKGKWVFLKPLTRELWFLTAASFLYIGIMVWIFEYQASGDFRKQSIINKISNVFYFSFSTLFFAHMRPSESIFTRVLVVVWCFVLLILTQSYTATLTSMLTVQELRPTVRHMDDLRNSGVNIGYQTGSFTFERLKQMGYKESRLKTYDTPQEMHELFLKKSSNGGIDAAFDEVAYVKLFMAKYCSKYTIIEPTFKADGFGFAFPLGSPLVPDLSRQILNITEGETMKAIENKWLLGEKHCLDSTTSDSPIRLDHHSFEALFTIVFVVSMLLLLAMLVCRRYRQESKSGEINANNSPTDGNMRAPPNQPTDDNMRAPTSPPIDDQVLEPPGPALNEADDQDQLLNDEVNVGDRNEVDIIVEVDPTLVHRRNLITSKTIPTRRAALFSRIKSA
What is the function of this protein?
Glutamate-gated receptor that probably acts as non-selective cation channel.  May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
What are the official names of this protein?
Glutamate receptor 2.6, Ligand-gated ion channel 2.6.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL4_BARQU
Sequence: MDLVIRTLDGNEAGRLKVSESIFGLVPREDILQRVVRWQLARHQQGTHHSQGRSDVSRTGAKMFKQKGTGRARHSSARAPQFRGGGKAHGPVVRSHAHDLPKKIRVLGLRLALSAKLKANDLIIVDELNVKEAKTKMLVSCFSKLGFKNALLVGGKEIDINFSRAASNIPNIDILPIQGINVYDILRRSKLVLSKAAVEALEERFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: MIAA_LEPBA
Sequence: MILPILGGPTGSGKTSLTQVLDPKRFEIVSFDSRQVYRDLPVGTTAPTPEECSTIRHWLIGFLNANESINANQFSLLARNAIADIQSRGKIPFLLGGTGFYLRAFLLGMYPVPTVPKETKDYVFTLPLEEARSQLLAKDPKAMESLSDQDGYRIKRALEVVLTGVLWSDVSKETVGGFWKDNPEVKIVGHWLDWPREILYQRINTRVETIIRGMLEETKEVLSKYGPDCPGLRTLGYNFALAFLNGMIDSNTFIEQLAQSHRNYAKRQITWFKKESFLSPISYDAAVQLYTNIEQR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MCD4_YEAST
Sequence: MWNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKNVIIQDKTKKTQ
What is the function of this protein?
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.  Ethanolamine phosphate on the alpha-1,4-linked mannose is essential for further mannosylation by GPI10 and is necessary for an efficient recognition of GPI lipids and GPI proteins by the GPI transamidase, for the efficient transport of GPI anchored proteins from endoplasmic reticulum to Golgi and for the physiological incorporation of ceramides into GPI anchors by lipid remodeling.  Also involved in non-mitochondrial ATP movements across membrane and participates in Golgi and endoplasmic reticulum function, Also required for the incorporation of BGL2 into the cell wall.
What are the official names of this protein?
GPI ethanolamine phosphate transferase 1, Morphogenesis checkpoint-dependent protein 4, Supersecretion of u-PA protein 21.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: TRPB_LEGPA
Sequence: MIKKELPDEFGHFGPYGGMFVADTLVHALKQLEHAYTKYRNDQDFLSELHTELKDYVGRPNPLYHAVHLSKKIGGAQIYLKREDLNHTGAHKINNTIGQALLAKRMGKTRVIAETGAGQHGVATATVAAKFGFQCVVYMGSEDIKRQSSNVYRMKLLGAEVVPVTSGSKTLKDALNEALRDWVSHVDDTFYIIGTVAGPHPYPQMVRDFQAIIGVEARAQHMEKTGRLPDALVACVGGGSNAIGLFYPFLNDQSVMIYGVEAGGKGIETGEHSASLIAGKPGVLHGNRTYLLCDEYGQVKDTHSVSAGLDYPGVGPEHAYLKDTGRVIYKAINDSEALDAFRLLTHTEGIIPALESSHAVAYAIQLAKTMSKEQSIIVNLSGRGDKDMHTVAAIDGITI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PG115_VACCA
Sequence: MDIFIVKDNKYPKVDNDDNEVFILLGNHNDFIRSKLTKLKEHVFFSEYIVTPDTYGSLCVELNGSSFQHGGRYIEVEEFIDAGRQVRWCSTSNHISEDMHTDKFVIYDIYTFDSFKNKRLVFVQVPPSLGDDSYLTNPLLSPYYRNSVARQMVNDMIFNQDSFLKYLLEHLIRSHYRVSKHITIVRYKDTEELNLTRICYNRDKFKAFVFAWFNGVSENEKVLDTYKKVSNLI
What is the function of this protein?
Late protein which is part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.
What are the official names of this protein?
Core protein OPG115, 27 kDa virion core protein.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG115 family.