PharMolix/UniProtQA huggingface dataset:
Protein: RBKTP_AZOC5
Sequence: MSVMGSGLFFFVVGPSGSGKDTLIEGAKAALGPTGRYVFARRAITRPADAGGEAHEALSVDQFDAVLAQGGFLIHWEAHGLKYGLRATLLDDMAAGRHVIANGSRAMVAALAERVPHLVVVEITAPEAVLAERLKGRGREGAENIAARLERKVPPFPESVTVIQVPNDSTPRAGIEKFVAALVAQTARLRLVRMAIETGRRNVAFLARGNTVVAAPDYLGPGRVDLIGEGRSIRAEVALVGDALLPSDAVGLSSEAFGALGLPEGAELVLTRTPVPESRAALRRKIQGATLDEGAYAQVVGDIVEGRYPDSEVAGFLVAADRSLSDDEVLALAKVRAKFASRITWDEPMVVDKHSMGGIPGSRITMIVVPIVAAHGLAIPKTSSRAITSAAGTADAMETLARVDLDSAEVRRTVERARGCIAWNGRLSHSALDDVMNAITRPLGLDSTRWSVASILSKKLAAGSTHVVIDLPFGARARVKGAGEAHEMARLFEQVGAGLGLTVEAIPTDGSAPIGRGIGPALEVRDVLWVLEDHSEAPPDLKEKALFFASRILAWDPAVGPDRARARAEELLASGAARAALERIVEAQGRWSEPVRPARLTHTVTAQNDGQVSDIDGFAVAGIARLAGAPLDKGAGIDLKARVGDVVRAGDPLFVIHASTAADLEAAAGAALAFDGYGIMMDGKAFRRINPER
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Bifunctional ribose 1,5-bisphosphokinase-thymidine phosphorylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: TRPD_BUCA5
Sequence: MRNILLKIYDSKFLNQEESYQLFTLISSGKITDIKLASILTAMKIRGESIEEITGAIKAFLDKMKYFPKPDYIFSDIVGTGGDAKNTINISTMSAFVAATCGLKIIKHCNQRISSKSGSSDILEKFNINLNASPEKSRKTLDQLNICFLFAPKYHDGFKYSNNVRTDLKTKTIFNFLGPFLNPATPPLSVIGVYNKNLINIAVNILKNLQYKRAIVLHSDNTDEVTLYGTTYVSELLNKKIISYQLQPESFGLKMHPKKILKINSLEENYHIIKEIMKGKGSKLYEELIAVNVAMLLKVFGYENLKENTKLALNKIRSGDVYKHIRNVANMLKEDNHARHNT
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CSTOS_MOUSE
Sequence: MVAPSGAMSDSENSSSSSSDAEELARCREAATPAWGLEQRPGAAERPEAGAADKQAPTPQPSRRHEVNQHEEDGNDLRTTPEFRAHVAKKLGALLDSSIAIAEVWKKSQKAKMQQVAKEEDGFRLFFTSIPGGHKKEASPRPCRKRQPPSSSEDSDEELQRCREAAVSASDILQESAIHCPAKAEEKKKLKKKAKKKVDNADLAAAPGLEQVKEAGVVNGDPVSLGIQKKRKKKAKKSREAPLCPPAECAAAKPEN
What is the function of this protein?
Plays a role in the regulation of Wnt signaling pathway during early development.
What are the official names of this protein?
Protein CUSTOS.
What is the protein family that this protein belongs to?
Belongs to the CUSTOS family.
What are the subcellular locations of this protein?
Nucleus envelope.
Protein: DCLK_DROER
Sequence: MEFDEIKKHSLNCNADVLSSLQASAPASSPHTVTLKVNAVAEATITEKRNQQQNVQKDFDSHNRDCDSPVSSTSELEKEFDDLRNLHTSSLTNSVVLGKSIGSLNGDYSVTSASSRTKTLENVVTIDSASGSTCLAIASPVDHIKKRIPNSRTPTRKALRIKFYRNGDRFYPGITIPVSNERYRSFERLYEDLTRLLEENVKIPGAVRTIYNMCGKKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLTLTNNSRSNNQRLAKCRPASPLKNGLLTGISPLPASGGGTGNGSPLIASRLSDRVSVVHPRIVTLIRSGTKPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGISVVQLSDFFGSDDVFFAYGTERINYAEDFKLEAEEYRAINVIRKTMRTAGTTCKGPKPKMPIKSKKVYPPLVDSEVLKAATSPEDDSHATLLTSTGIEINELPLNIRNTYTLGRIIGDGNFAIVFKIKHRQTGDSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSESQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQSDPDVRFTSEDILDHYWTIGNKGNDL
What are the official names of this protein?
Serine/threonine-protein kinase GG21441, Doublecortin-like and CAM kinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: NSRR_ALIF1
Sequence: MQLTNFTDFGLRALIYLGSLPEGELTSITVVTETFDVSRNHMVKIINKLGQEGYVKTIRGKNGGICLGKPADQIIIGDVIRAIEPLQVVNCAPEFCHITPACRLKGALAKAKQAFLDELDKHTIQDMLTDNSELLILLKRI
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: ATPA_WOLTR
Sequence: MKNSINTSEIVNIIREKVEAFDNPIKKENIGEVISVTDGIALVYGLEKAKFGEKVFFTSGVEGIVLDLDHDTAGIVVLGNDRDVKEGDTVKCSGDVMQVPVGHELLGRVVNALGHSIDNSGEIRSKNRMDMESKAPGIIDRKSVHEPLQTGIKIIDLLIPIGRGQRELVIGDRQIGKTTIALDTIVNQKKINDEVDENQKVYCVYVAIGQKISTVAKVVNKLKESGALEYTTVVVASASDCAPMQFLAPYAGCTIGEFFRDNGMHCLVVYDDLSKHAVAYRQMSLLLRRPPGREAYPGDIFYVHSRLLERAAKMSDEKGRGSLTALPIIETQAGDVSAYVPTNVISITDGQIFLESELFHKGFRPAVNIGLSVSRVGSAAQLKSVKKVAGSIKLSLAQYRELEDFAKFGSDLDASVQLSLNKGKYLVELLKQKQHLPMPVEEQVVLMYIFSNLYDQLSRIQISDINKFKYDLINYFHTTYPEVLKKLSDSMSDDIKDDIFNIVSNFVAQFNGV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PR8A9_RAT
Sequence: MELPLSQAQFSGTFLMLAVSNMLLWEKVSSIPACLAEEGGCWNPIVETFNSAMQRGETLRNLADQLYTELYHNQFSSEQFLALNSKLIRRDKTAVRAGTYCHSTLSNSPDGETKHADVETEKYLKMLINFVGAWISPLYHLVIELSAMQDVPETILSKAKDIEENKRELLDDLKWILTKVYPTAEMKEEFPSWEHLSFLKSSNKDSKFLAMFNLSKCIYNETYYILFYLRTLKCHITGKDC
What are the official names of this protein?
Prolactin-8A9, Placental prolactin-like protein C2, PLP-C2, PRL-like protein C2, Prolactin-like protein C-beta, PLP C-beta.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSP1_PETXA
Sequence: MARYRHSXSRSRSRYRRRRRRRSRYRSRRRRYRGRRRRRSRRGRRRRGYSRRRYSRRRRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: OTC_YERPS
Sequence: MNQFYKRHFLRLLDFTPAEIIALLDLATELKKDKKSGCEQQKLVGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPGGSQIGHKESIKDTARVLGRMYDGIQYRGYGQRVVETLAEFAGVPVWNGLTNEFHPTQLLADLLTMREHLPNKSLNKMTLAYLGDTRNNMGNSLLEAAALVGMDLRLVAPKACWPEEAFVISCQALAQKTGGKITLTEDIAEGVNGADFLYTDVWVSMGEPKEVWQERITLLKPYQVNMRVLTLTGNPQVKFLHCLPAFHDDQTTIGKQMAEQYDLPGGMEVTEEVFESAHSIVFDQAENRLHTIKAVMVATMSKI
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPS1_YEAST
Sequence: MVLLHKSTHIFPTDFASVSRAFFNRYPNPYSPHVLSIDTISRNVDQEGNLRTTRLLKKSGKLPTWVKPFLRGITETWIIEVSVVNPANSTMKTYTRNLDHTGIMKVEEYTTYQFDSATSSTIADSRVKFSSGFNMGIKSKVEDWSRTKFDENVKKSRMGMAFVIQKLEEARNPQF
What is the function of this protein?
Required for maintenance of normal mitochondrial morphology (PubMed:16754953, PubMed:26071601).  Required for PCP1-dependent processing of MGM1 (PubMed:16754953).  The UPS1:MDM35 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space (PubMed:26071602, PubMed:26071601, PubMed:26235513).  Phosphatidic acid release requires dissociation of the UPS1:MDM35 complex (PubMed:26235513).  Phosphatidic acid import is required for cardiolipin (CL) synthesis in the mitochondrial inner membrane (PubMed:26071602).  With UPS2, controls the level of cardiolipin in mitochondria (PubMed:19506038).  Cardiolipin is a unique phospholipid with four fatty acid chains and is present mainly in the mitochondrial inner membrane where it stabilizes the electron transport chain supercomplex between complexes III and IV through direct interaction of their subunits.
What are the official names of this protein?
Protein UPS1, mitochondrial, Unprocessed MGM1 protein 1.
What is the protein family that this protein belongs to?
Belongs to the slowmo family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Mitochondrion intermembrane space. Note=Lacks the two major intermembrane space-targeting signals, bipartite presequences and cysteine motifs, and import is mediated by another IMS protein, MDM35.
Protein: IOLC2_BACCZ
Sequence: MNPLIFKEDCPLDLIAVGRLCVDLNANETQRPMEATRTFTKYVGGSPANIAIGATRLGLQTGFIGKVSDDQMGRFITRYLQDNNINTDQICIDRTGAVTGLAFTEIKSPEDCSILMYRDNVADLNLDPTEVSEDYIKQSKALLISGTALAKSPSREAVFLALEYARKHDVVVFFDVDYRPYTWQSEAETAVYYNLAAEKSDVIIGTREEFDMMEKLLNYEESNDQVTAERWFSHHAKIVVIKHGGDGSIAYTRDGQSHRGGIFKTKVLKTFGAGDSYASAFIYGLMQGLEIPQAMRLGGASASIVISKHSCSDAMPTRAEISAFMEIAEEIV
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase 2, 2-deoxy-5-keto-D-gluconate kinase 2, DKG kinase 2.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: RL27_LISMC
Sequence: MLKFDIQHFAHKKGGGSTSNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGTNVGRGGDDTLFAKTDGVVRFERMGRDKKKVSVYPEVQEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RNH2_HELP2
Sequence: MILGIDEAGRGCLAGSLFVAGVACNDQTALELLKMGLKDSKKLSLKKRFFLEDKIKTHGKVKFFVVKKSANEIDNLGLGACLKLAIQEILENNRSLANEIKIDGNTAFGLNKRYPNIQTIIKGDETIAQIAMASVLAKAFKDREMLELHALFKEYGWDKNCGYGTKQHIEAITKLGATPFHRHSFTLKNCILNPKLLEVEQRLI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_CALBD
Sequence: MAQPKRRWSKQRTHKHRANWKLEIPNLTECPQCHEMKLPHRVCPNCGYYRNRKVVNQD
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: TRX2_HHV7J
Sequence: MDSIYCTFDQKLTLSDIGTLCKLTNAVIPIPSHRHLIGNTNLGLYTVLSTTTDYIQIRDILKTMVLTILQKVEGNQLILIRPKIGHQYEIKNTGPFPLEKGDQLSLLPPFLKPSQQLLVLPNWELILPLLIPTDVATEINVRMLCISLLSIHRKYEEVQIIIDELRTLQYRDVTIKLPDVINDCKSTFSMKTACISFSMIATMAPDIVQTYIERLSLEDQSMLLIKCQELLAKKNFSQEPSSFKATEIKTELQKIKTVFTMINQINSLTQEKTFFIVADVSADNRLATCIFKE
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PG065_VACCW
Sequence: MSKIYIDERSNAEIVCEAIKTIGIEGATAAQLTRQLNMEKREVNKALYDLQRSAMVYSSDDIPPRWFMTTEADKPDADAMADVIIDDVSREKSMREDHKSFDDVIPAKKIIDWKGANPVTVINEYCQITRRDWSFRIESVGPSNSPTFYACVDIDGRVFDKADGKSKRDAKNNAAKLAVDKLLGYVIIRF
What is the function of this protein?
RNA-binding protein that plays a role in the inhibition of multiple cellular antiviral responses activated by double-stranded RNA (dsRNA), such as inhibition of PKR activation, necroptosis, and IFN-mediated antiviral activities (PubMed:1681618, PubMed:18604270, PubMed:24257616, PubMed:25740987).  Recognizes and binds Z-RNA structures via its Z-binding domain and dsRNA via its DRBM domain: RNA-binding activity is required to escape host ZBP1-dependent necroptosis (PubMed:29073079, PubMed:34192517).  Mechanistically, the Z-binding domain binds Z-RNAs that are produced during vaccinia virus infection, thereby competing with Z-RNA detection by host ZBP1, suppressing ZBP1-dependent necroptosis (PubMed:34192517).  Acts as a key inhibitor of the interferon response by blocking the phosphorylation and subsequent activation of IRF3 and IRF7 kinases that are required for interferon-alpha gene expression (PubMed:22419806).  Inhibits NF-kappa-B activation and the ubiquitin-like protein ISG15, which is an early antiviral protein (PubMed:18604270, PubMed:24257616).  The binding with host ISG15 subsequently blocks host ISGylation (PubMed:18604270, PubMed:24257616).
What are the official names of this protein?
RNA-binding protein OPG065, RNA-binding protein E3, p25.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG065 family.
Protein: NTPP_MYCLE
Sequence: MTRLVLGSASAGRLKVLRQAGIDPLVAASGVDEDLVTAGLGSDTSPRDVVSTLARAKATQVAAALSHAVADDCVVISCDSQLSIDGRLYGKPQSVANARQQWQSMAGRAGQLYTGHCVIRLLNNETTYSVDETSMTTICFGNPSAEDLEAYLACGESLQVAGGFTLDGLGGWFIDAVYGDPSTVVGIGLPLTRSLLSRAGLSIAAMWAANPVI
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_GEOSW
Sequence: MATNEEHLRKPEWLKIKLNTNENYTGLKKLMRENRLHTVCEEAKCPNIHECWAVRRTATFMILGNVCTRACRFCAVKTGLPTELDWQEPERVAESVRLMNLKHVVVTAVARDDLKDGGAAVFAETVRAIRRKNPFTTIEVLPSDMGGVYENLKTLMDARPDILNHNIETVRRLTPRVRARATYERSLEFLRRAKELQPDIPTKSSIMVGLGETKEEIIEAMDDLRANHVDILTIGQYLQPTKKHLKVVKYYHPDEFRELKEIALSKGFTHCEAGPLVRSSYHADEQVNAASAARQMKA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YH73B_YEAST
Sequence: MYFHSFLDTFSKYLGSTSCPLLRLSR
What are the official names of this protein?
Uncharacterized protein YHR073C-B.
Protein: CYB_AKOML
Sequence: MKXLRKNHPLFKIINHSFIDLPTPSNISSWWNFGSLLGMCLMIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYVLSETWNIGIILFLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGSTLVEWIWGGFSVDKATLTRFXAFHFILPFIITAFVLVHLLFLHETGSNNPSGLNSNSDKIPFHPYYTIKDLLGILFLLTALMILALFFPDILGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILMAFPLLNTSKQHGLIFRPITQTIYWILIANLLVLTWIGGQPVEYPFTMIGQIASITYFAIILILMPVSNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PANC_PSEMY
Sequence: MNTVKTLRELRAAVAQARAEGKQIGFVPTMGNLHAGHASLVQIAAQRADFVVASIFVNPLQFGAGEDLDKYPRTLAADQERLLAAGCHLLFHPDAAEMYPHGMGDQTRVTVPGVSEGLCGASRPGHFEGVATVVTKLFNMVQPDLAVFGEKDYQQLAVIRALVQDLNMPIQIIGAPTQRAEDGLALSSRNGYLSAEQRAVAPALYRSLQSIAEALHHGARDYARLIETAQTQQREAGFTPDYLEIRNALNLRPAQLDDRHLVVLTAAHLGSTRLIDNLLVELAGQ
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CHOCR
Sequence: MRFIKRPLISIVNDHLIDYPTPINIHYAWNFGFLSSICLIVQILTGIFLAMHYTPHVDLAFASVEHIMRDVNYGWLLRYIHTNGASMFFIVVYIHIFRGLYFGSYIKPRHWVWVIGVLILLLMILTAFIGYVLPWGQMSLWGATVITNLVSAVPFIGDSIVTWLWGGFSVDNATLNRFFSLHYLMPFVIAAVSLVHLAILHQDGSGNPLGIDSNVDKVSMFPYFIVKDFLGMVIFIIFFSIFVYFSPNVLGHPDNYIEANPMVTPAHIVPEWYFLPFYAILRSIPHKLGGVTAMISAIAILAFLPWIHSTEIRSSRFRPLYRLFYWVMISCCLILGWIGGMPVENPYVIIGQIASIYYFIYFIILLPVLGRIEKFLLEFKI
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACPS_ACIF2
Sequence: MIVGMGTDIVAVERMARLHARFGERLTERLLGPLEVADMPVEAAAGAAFLARRFAAKEATFKALGSGMTNGMRWMDVQVGHDSGGRPQLVLGGRAQQLLRGLGDGVRSWLSISDERRYAMAVVVLERGG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR14_MARPO
Sequence: MAKKSLIQREKKRQNLEKKYKILRNSLKKKITETSSLDEKWEFQKKLQSLPRNSAPTRLHRRCFLTGRPKANYRDFGLSRHLLREMAHACLLPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YHIY_ECOLI
Sequence: MMTTLLPVFTKPSPLALNALRAGRICRFLLIPDGRIR
What are the official names of this protein?
Protein YhiY.
Protein: CAH5A_MOUSE
Sequence: MLRRDPRKPLAILRHVGLLCATGPQRWRFQHSCAEEHSNCARHPLWTGPVSSAEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGYFFQVEFDDSCEDSGISGGPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGLAVIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGPFDPSCLLPACRDYWTYPGSLTTPPLAESVTWIVQKTPVEVSPSQLSTFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFRLDRTKMRS
What is the function of this protein?
Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3 (PubMed:7937950).  Mitochondria are impermeable to HCO3, and thus this intramitochondrial carbonic anhydrase is pivotal in providing HCO3 for multiple mitochondrial enzymes that catalyze the formation of essential metabolites of intermediary metabolism in the urea and Krebs cycles (By similarity).
What are the official names of this protein?
Carbonic anhydrase 5A, mitochondrial, Carbonate dehydratase VA, CA Y, Carbonic anhydrase VA, CA-VA.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y4JN_SINFN
Sequence: MLSATDLANRKFGSGDRIHVGGKAAARYGYDLSSSRSAHVAAADHLIGWFLAGFRQRIHKPFMLRTVQCDRIYVLAGPNLEAQWDVVAWTKLVHEPAYAVGLVSRWVLMTSHHMSCVVQGSRLGNRPRKCVMQRFSVAMRNIVRVG
What are the official names of this protein?
Uncharacterized protein y4jN.
Protein: CRFR1_MOUSE
Sequence: MGQRPQLRLVKALLLLGLNPVSTSLQDQQCESLSLASNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHIAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEVHQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
What is the function of this protein?
G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin).  Has high affinity for CRH and UCN.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase.  Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.  Inhibits the activity of the calcium channel CACNA1H.  Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress.  Plays a role in the response to anxiogenic stimuli.
What are the official names of this protein?
Corticotropin-releasing factor receptor 1, CRF-R-1, CRF-R1, CRFR-1, Corticotropin-releasing hormone receptor 1, CRH-R-1, CRH-R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome. Note=Agonist-binding promotes endocytosis.
Protein: HIS4_BUCAI
Sequence: MIIPAFDLINGRTVRLYQGDYSNQKNYNVNLFNSLEVYKSKGIEIVHLVDLDGAKNSANRQIELFKKIVSHTTVPVQVGGGIRTTKDISTLLDLGVKRVVIGSSIVSNKKQVKQWLNFYGPDAIVLALDVHVDGSNKKEISIDGWQKKTNFILEEIIEYFLSSGLKHVLCTDISRDGTLLGPNFKLYKEICSNFKNINFQASGGVASLQDIIFLKKTGVKSIIIGRSLLEKKFTIEEAVKCWQRES
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPB_PASMU
Sequence: MPMQIMLSTQVADEAWGKNALLSFHQAQATIHVTDYSARNTVQKAARKLRGQGIKDVVLAGENWDLETCWAFYQGFYSAKQDYAVEFPTLDDAPQAELLARIQCGDFVREMINLPAEVITPVELARRAAHFIEEQAEEYGDKSAVSFNIISGEELKAQNYQGIWNVGRGSANPPAMLQLDFNPTGNPDAPVLACLVGKGITFDSGGYSIKPSDNMSTMRTDMGGAALLTGSLGLAIARGLTQRVKLYLCCAENLVSSNAFKLGDIITYSNGVTAEILNTDAEGRLVLADGLIEADKQQPKMIIDCATLTGAAKMAVGNDYHSVLSMDDALVAALFKSAETEQEPFWRLPFAELHRSQISTAFADIANTGTVPVGAGASTATAFLSYFVKNYQQHWLHIDCSATYRKTASDLWAVGATGIGVQTLANLLLNPVKG
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.