PharMolix/UniProtQA huggingface dataset:
Protein: EED_BOVIN
Sequence: MSEREVSTVPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
What is the function of this protein?
Polycomb group (PcG) protein.  Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene.  Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark (By similarity).  The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity).
What are the official names of this protein?
Polycomb protein EED.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ESC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIG_PROMA
Sequence: MNNNSSSLSIGNKLFKSRLLIGTGKYQTLNQMQESIINSECEIVTVAVRRVQSSESSHKGLMEAIDWKKLWMLPNTAGCTNSEEAIRIAKMGRELAKLSGQEDNNFVKLEVIPDNRYLLPDPFGTLEAAEALIKEGFVVMPYINADPLLAKRLENIGCSCVMPLGSAIGSAQGIRNESNIRIIIENSNVPVIVDAGIGVPSHAAEAMEMGADAVLINSAIALAKDPKSMAEGMCKGVHAGRKAFLAGRLVEQPLANPSSPCTEISKSSYVQ
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_LISMO
Sequence: MAKEKIVLAYSGGLDTSVAIQWLVESGYEVIACCLDVGEGKNLDFIKEKAITVGASESYTIDAKEEFAEDFALIALQAHAYYEGKYPLISALSRPLIAKKLVEVARQEGASAIAHGCTGKGNDQVRFEVAIHALAPDLKVVSPVRDWKWSREEEINYAKEHDIPVPIDLDNPFSIDQNLWGRSNECGVLENPWTTPPEAAYDLTVSLEDAPDTADIVEITFDAGIPISLNGENMSLANLILTLNEIAGKHGVGRIDHIENRLVGIKSREVYECPAAVTLITAHKELEDLTFVREVAHFKPIIEQKISETIYNGLWFSPLTEALVAFLKSTQKFVNGTIRVKLFKGHAIVEGRKSPNSLYDENLATYTSSDTFDQDAAVGFIKLWGLPTKVNAEVNSKVTITTEV
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAL1_XENLA
Sequence: MAKATTIKEALAKWEERTGQKAGEAKEVKLYAQIPPLEKMDASLSTLVNCEKLSLSTNCIEKIANLNGLKYLKILSLGRNNIKNLNGLEAVGETLEELWISYNLIEKLKGIHVMKKLKVLYMSNNLVKDWAEFSKLGELPLLGDIVFVGNPLEEKHTAEGNWMEEAVKRLPKLKKLDGNPVIKQEEEEGDES
What is the function of this protein?
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity).  Component of the outer arm dynein (ODA).  May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity).
What are the official names of this protein?
Dynein axonemal light chain 1.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain LC1-type family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: HUTI_MYCS2
Sequence: MTTLLIDNIGSLVTNDPTLDAGPLGVLRDAAVVVEDGRIAWYGATSAAPAADTRLDAAGRAVIPGFVDSHAHLVFAGDRSEEFAARMSGTPYQAGGIRTTVTATRDATDATLKSTVTRLAAEALRSGTTTLECKSGYGLTVEQELRSLQVAAEITDEVTFMGAHVVPPEYAETPDDYVELVCTAMLDACAPAAKWVDVFCERGAFDLDQSRAILQAGIARGLQPRVHANQLGPGPGVQLAVECNAASADHVTHVSDADIAALAGSNTVATLLPAAEFSTRAAYPDGRRLIDAGVTVALSPDCNPGSSFTTNMPFCIAVAVREMHLTPDEAVWAATAGGARALRRDDVGHLAVGARADLALLDAPSHIHLAYRPGVPLVAAVLRNGEIVWQTKEVTS
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_YERPS
Sequence: MLTRLFVTGTDTAVGKTVVSRALLQALSQNGRTAVGYKPVATESKETSEGLRNQDALILQASSSIELNYQEVNPYPLQGDVIHACTDTLINYEKMTEGLQCLSAKADTVIVEGCGGWKVMMNDQRFYSDWVVQEQLPVILVVGIKLGCINHALLTAQAIINDGLPLLGWVANRINPGLAHYAETIAMLRDRLAAPQLGQLPYLPRPEEKPLAKYLDLTAISG
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_EHRRG
Sequence: MSDHVKITPMTLNFGPQHPAAHGVMRLVLEMGGEVIERIDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSPMAQEHAYSLCVEKLLKCEVPIRAKYLRVIFCELTRILNHLLNISSQALDIGAMTPLLWMFEEREKILNFYERASGARFHSAYIRPGGVAADIPEDLIHDIFQFVNTFPKFMDDVDSLLTENRIWKQRNVDIGVVSKKQALNWGFSGPMLRACGIPWDLRKSQPYEIYDELEFKIPIGEKGDCYDRYLVRMAEIRESISLVEQCLNRIPDGPVKTDDRKIAPPKRSEMKKSMEALIHHFKLYSEGYIVPAGETYMAVEAPKGEFGVYIVSDGTNKPYRCRIRAPGFAHLQAIDMMAKGHMLADLTAIIGSLDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MADS3_ORYSJ
Sequence: MGRGKIEIKRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRLYEYANNSVKSTVERYKKANSDTSNSGTVAEVNAQHYQQESSKLRQQISSLQNANSRTIVGDSINTMSLRDLKQVENRLEKGIAKIRARKNELLYAEVEYMQKREVELQNDNMYLRSKVVENERGQQPLNMMGAASTSEYDHMVNNPYDSRNFLQVNIMQQPQHYAHQLQPTTLQLGQQPAFN
What is the function of this protein?
Probable transcription factor involved in the development of floral organs.  Acts as C-class protein in association with MADS58.  Involved in the control of lodicule number (whorl 2), stamen specification (whorl 3) and floral meristem determinacy (whorl 4), but not in the regulation of carpel morphogenesis.  Plays a more predominant role in controlling lodicule development and in specifying stamen identity than MADS58.
What are the official names of this protein?
MADS-box transcription factor 3, OsMADS3, Protein AGAMOUS-like, RMADS222.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y478_RICPR
Sequence: MKKILIIILFIIIFIVLIYSGLWFVIMFSLSHSINQKYSGVHLNIGKGNNNPHQQYLVKFSKVQPYGFPFKLGIMVINWQEESINRAIEFTKPINIGYDLLGQKLFINFSGEALGKFKPVQRGFGVKFYNENCILSAKIPLNLKLFKMVLLKKNLFEFLNLIENIKFISDKTQIFDLVDNQKLYEEDHTILTMLVDKRQYYTSKQDFLNNIPQKLEFYYETEIIQSNLEDRIIPAGLLLYRPAWNNNFKFSGNFLISTSSLHFKDIAKDLTIKVNNAKINSNNFENNMNLLYKGKLNDFGNSNIHLSIESQFKLKPGFIIGFLEFLKKNYDKQTYLLKFSDNKIYKNFNNELVYILNNNKPYNFSILEDRPYHFNFNINLVTELKKLTRVQINTLSLYSNTSGFNITNETIINDLKDSYTKGIIVINNYSKIIEILSFYIYGVGSFKNLSKESQIVHIEALQSFLKTISDHPNSSNLIDTSIKYEFNLSDLNKAKIGNIDDINKLIPLYYLSLYQAAVKKMEPGANVKEKILELIPSINQKILEECVLSDIVTQ
What are the official names of this protein?
Uncharacterized protein RP478.
Protein: NAA35_MACFA
Sequence: MVMKASVDDDDSGWELSMPEKMEKSNTNWVDITQDFEEACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAIKDGTIKIKDLTLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANSVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAVFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHNSLHHGIQAQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVSYFARLIDRIKTVCEVVNLTNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCYLYNNHQAKDCIDSFVTHCVRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLNKYSPPPQSPELYVAASKHFQQAKMILENIPNPDHEVNRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSAHKYFPVVKLV
What is the function of this protein?
Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.  Involved in regulation of apoptosis and proliferation of smooth muscle cells.
What are the official names of this protein?
N-alpha-acetyltransferase 35, NatC auxiliary subunit, Protein MAK10 homolog.
What is the protein family that this protein belongs to?
Belongs to the MAK10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_LEIXX
Sequence: MPRKGPAPKRPVVADPVYGSPVVSQLVNKILLDGKKGLAERIVYDALEGVSSKSGNDAVATLKKALDNIRPTLEVRSRRVGGSTYQVPVEVKPHRANTLALRWLTSYAKGRREKTMTERLANEILDASNGLGAAVKRREDTHKMAESNKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: F16PA_SHESA
Sequence: MQTLAQHLTSKAVNESLSQLILTLADTSKAISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRGLASEEEDHVVEVCANGQYLVCFDPLDGSSNIDINSLVGTIFSVLPAPQGELTETSFLQSGRNQLAAGYVLYGPSTMLALTTGQGVQLFTLHPETNEFLLTNAAMSISPDTQEFAINMSNQRFWEAPMQTYIADLLLGKIGPREKSFNMRWIAAMVGDVHRVLSRGGIFTYPTDNKDPKKPYKLRLMYEANPMALLVEQAGGKASTGYETILDIQPTQIHQRVAVILGSANEVDACLSYHGLDYSEEPSLD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEGTB_XENLA
Sequence: MRNCCRERGFSVGRLEPETSFSCASDVKSSPDMDSVSSQDSLYLPNSIGASLEDQNLWTQFHQEGTEMIITKSGRRMFPQCKIRLFGLHPYTKYMLLVDFVPLDNFRYKWNKNQWEAAGKAEPHPPCRTYVHPDSPASGAHWMKDPICFQKLKLTNNTLDQQGHIILHSMHRYKPRFHVVQSDDMYNSPWGLVQVFSFPETEFTAVTAYQNEKITKLKINHNPFAKGFREQERSHKRDDVLKTLQQSPSKSQKRKKWEDSPEADISDFPKATRIKEESIMDPAGVYQNWVSDHEANQGLTPHSPESEGVNQEQQVPTSSSNFYIKSQYRRSSQHLSSPYDLGEPSSRRLTPDVATVPDSDPDSLAVLHVIPTQNSAQERTCSMNFSMETPMKQPLRGAIYSPYGTEQWMVPAQGPYQPVSYTAYPTDLSAQGAVAHPHSGMSDWSQYSLFPYSCW
What is the function of this protein?
Transcription factor required for both mesoderm and endoderm formation in the embryo; signaling determinants and concentration levels may determine which germ layer is formed.  Acts together with beta-catenin to activate genes that are responsible for mesoderm induction including wnt-8, eomes t/bra, siamois, mix1 and sox17.  Directly binds to promoter DNA.  Patterns the mesoderm along the dorsoventral and posterior axis.  Activates siamois gene transcription when alone or in combination with beta-catenin, but inhibits siamois transcription in combination with pou5f1. 1/oct-25.
What are the official names of this protein?
T-box protein VegT-B, Xenopus optomotor blind, Xombi.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEPA_RUEST
Sequence: MTELSKIRNFSIVAHIDHGKSTLADRLIQSTGTVQDRDMKEQLLDAMDIERERGITIKANTVRIDYEADDGERYVLNLIDTPGHVDFAYEVSRSMRAVEGSLLVVDSTQGVEAQTLANVYQAIDADHEIVPVLNKIDLPAADCDRVAEQIEDVIGIDATDAIRVSAKTGIGIKDTLEAIVKRLPAPTGERNAPLKAMLVDSWYDAYLGVIVLVRIMDGVLKKGDQIKMMQTNARYGVDRIGVFRPAMQVVDELGPGEIGFITASIKQVRDTKVGDTITHDKKGAETALPGFKPSVPVVFCGLFPVDSSEFEDLRDAIEKLALNDASFSYEMETSAALGFGFRCGFLGLLHLEVIRDRIEREYNIELITTAPSVVYHIFMKDGEMLELHNPADMPDLSKVDHLEEPRIKATILVPDEYLGDVLKLCQDRRGIQQDLSYAGSRAMVVYDLPLNEVVFDFYDRLKSVTKGYASFDYQMIGYRADNLVKMSVLVNDEPVDALSTMVHRDRAEQRGRAMCEKLKDLIPRHMFKIPIQAAIGGKVIARETLSALRKDVTAKCYGGDATRKRKLLEKQKAGKKKMRQFGRVEIPQEAFISALKMDD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NUB1_BOVIN
Sequence: LGLRACDGNVDHAAVHIANRREELDQIKKEEREKKKRRLENINHLKGMGYSMRAARQALHQAAGNLEEALKILLHNPQLWWLNDSAPESNNRQQSPSQEKIDQLVYMGFDAVAAKAALRVFRDNVQLAAQTLVHNGGRLPPDLQLSAEDSSSTPSTSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVENIKSAAKKN
What is the function of this protein?
Specific down-regulator of the NEDD8 conjugation system.  Recruits NEDD8 and its conjugates to the proteasome for degradation (By similarity).
What are the official names of this protein?
NEDD8 ultimate buster 1, Negative regulator of ubiquitin-like proteins 1.
What are the subcellular locations of this protein?
Nucleus. Note=Predominantly nuclear.
Protein: TLP8_ORYSJ
Sequence: MSFRSIVRDVRDSFGSLSRRSFEVTLAGLSGLTGHHRGKSQSTVHELCDADLIIQESRWASLPPELLRDVIRRLEASESTWPSRKDVVSCAAVCKAWREMCKEIVLSPEFCGKLTFPLSLKQPGPRDGMIQCFIKRDKSKSTYHLYLCLSTAVLADSGKFLLSAKRHRKTTCTEYVISMDADNISRSSSTYIGKLRSNFLGTKFIIYDTQPSYNGAVIPPVGRSSRRFNSKKVSPKMPSGSYNIAQVTYELNVLGTRGPRRMHCVMHSIPASSVEPGGIVPGQPEQIVPRAFEESFRSTTSFSKSSIMDRSMDFSSSRDFSSARFSDIAGGTINGDEEGQNKERPLVLRNKAPRWHEQLQCWCLNFRGRVTIASVKNFQLIAAPAQPPAGAPTPSQPAPPEQDKIILQFGKVAKDMFTMDYRYPLSAFQAFAICLSSFDTKLACE
What are the official names of this protein?
Tubby-like F-box protein 8, OsTLP8, Tubby-like F-box protein 1, OsTLP1.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
Protein: AROB_BACSU
Sequence: MKTLHVQTASSSYPVFIGQGIRKKACELLTSLNRPLTRIMFVTDEEVDRLYGDEMLHLLQEKWPVKKVTVPSGEQAKSMDMYTKLQSEAIRFHMDRSSCIIAFGGGVVGDLAGFVAATFMRGIDFIQMPTTLLAHDSAVGGKVAVNHPLGKNLIGAFYQPKAVLYDTDFLRSLPEKELRSGMAEVIKHAFIYDRAFLEELLNIHSLRDITNDQLNDMIFKGISIKASVVQQDEKEEGIRAYLNFGHTLGHAVEAEYGYGQITHGDAVALGMQFALYISEKTVGCEMDRKRLVSWLKSLGYPSQIRKETETSVLLNRMMNDKKTRGGKIQFIVLNELGKVADHTFSRNELESWLNKWRLEETS
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_LISMH
Sequence: MKLITNKQGLVGAITVPGDKSMSHRSIMFGAIAEGKTVIRHFLRADDCLGTIKAFKALGVKIEETEEEIIVHGTGFDGLKQADGPLDIGNSGTTIRLMMGILAGRDFDTVILGDESIAKRPMNRVMLPLQQMGAKMHGKDGSEFAPITINGKQSLKRMEYHMPVASAQVKSAIIFAALQAEGETIIHEKEKTRDHTEHMIRQFGGEIEMDGLTIRVKGGQTFTGQEMTVPGDVSSAAFFIVAGLITPGSEIELTHVGLNPTRTGIFDVVEQMGGSLVVKDSSRSTGKLAGTVVVKTSDLKGTEIGGDIIPRLIDEIPVIALLATQAEGTTIIKDAAELKVKETNRIDAVATELNKMGADITPTEDGLIIRGKTPLHAANVTSYGDHRIGMMLQIAALLVEEGDVELERAEAVSVSYPTFFEDIRSLLK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADD_CLOAB
Sequence: MNIKEQIINLPKVELHCHLDGSLRPETVLDLCLKENINIPYENPEDFKSSLKISKNCSSLKEYLEKFYFPIRVMQKKENIYRVTMELLEDSKKDGIEYTEIRFAPFQHTEQDLNENDVVEAALEALQDGESKLGIHSNLILCSLRHDPVERSIDLVNLANSYNEGVCAVDLAGNESDFPPELHKEAFDLAYDNGIKITIHAGETGIAENILKSIKLLHADRIGHGIFAYKSEEILQYVIENQVPLEMCPKSNVDTKAVKNYKNHPFKKYFDLGVKVTLNTDNRTVSNVSLVDEYLNLANIFDFGIEEIKTVIRNGISASFATEEFKVNLLKKLD
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: DAPD_RALSO
Sequence: MSQQLQSLIEQAWEDRANLSPKAAPNDVRAAVANVIDQLDQGALRVAEKKDGQWIVNQWVKKAVLLSFRLEDNAPMTAGGFTHFYDKVPSKFASYTADDFARGGFRVVPPAVARRGSFIGKNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVHYGRVPAGSVVVPGNLPSKDGTYSLYCAVIVKKVDAQTRAKTSLNELLRGD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AUSU_EMENI
Sequence: MTIIPKRSYNVLTTCKAVFRDVGDYWLTTGNLRTTKPQSPAQGFHRDTLLYPVLQYQPATSPSLIVTLLVSMTDATVANGATRVILSSQNGRLLNTIGGPGRASRAKRWGHAGNPSAAAARWWEAYESGTEYKTNATNFLHKMLASCS
What is the function of this protein?
Iron/alpha-ketoglutarate-dependent dioxygenase; part of the gene cluster B that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids (PubMed:22329759).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:22329759).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:22329759).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (PubMed:22329759).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (PubMed:22329759, PubMed:23865690).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (PubMed:22329759).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (PubMed:22329759).  Finally, the cytochrome P450 monooxygenase ausG modifies austinolide to austinol (PubMed:22329759).  Austinol can be further modified to dehydroaustinol which forms a diffusible complex with diorcinol that initiates conidiation (PubMed:22234162, PubMed:22329759).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end products of the Emericella nidulans austinoid biosynthesis clusters are austinol and dehydroaustinol, even if additional enzymes, such as the O-acetyltransferase ausQ and the cytochrome P450 monooxygenase ausR are still functional (PubMed:29076725).
What are the official names of this protein?
Iron/alpha-ketoglutarate-dependent dioxygenase ausU, Austinoid biosynthesis clusters protein U.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: SSUB1_NOCFA
Sequence: MSTEPIAVSITGLRKSFGDKTVLDGVDLTIRRGEFVVLLGPSGTGKTTLLRLLTGLEVPDAGEVLVPGRRTTVYQEPRLIPSKRVLANVLVGLRRTRSNRAAGLAALAEVQLDGKADQWPATLSGGEAQRAALARALVREPELLLLDEPFAALDALTRLRMQDLVGDLVARHRPAVLMVTHDVDEAVRLADRVIVLDRGRFAVDTAITAPRPRERADPDILRYQTEFLAHLGVGGSDRRPIRSAS
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PNP_NOVAD
Sequence: MFDVKTVSLEWGGKTLTLETGRIARQADGAVLATYGETVVLCAVTAAKSVKEGQDFFPLTVHYQEKYSAAGRIPGGFFKRERGATEKETLVSRLIDRPVRPLFPEGFYNEINVIAQVLSYDGETEPDIVAMIAASAALTISGVPFMGPIAAARVGFIEGEYVLNPKQDVALADGRLDLVVAATDTAVMMVESEAKELSEDEMLGAVLFAHDEIKKVIGAIIQLAEKAAKDPWDIDLSDNTADIKKKLKDLVGKDVAAAYKLTDKSARSNALNEARAKAKAAFAEEGAQTQMVAMKTMKKVEADIVRGAILKDGQRIDGRTTTQVRPIEAIVGFLPRTHGSSLFTRGETQAICTTTLGTKDAEQMIDGLEGLRYENFMLHYNFPPYSVGEVGRFGAPGRREVGHGKLAWRALHPVLPTKEEFPYTIRILSDITESNGSSSMATVCGGCLSMMDAGVPVKRPVSGIAMGLILEGDKFAVLSDILGDEDHLGDMDFKVAGTSEGITTMQMDIKVAGITREIFEVALRQASEGRAHILGEMTKALGEARTELSAHAPRIETLQIDKSKIRDVIGTGGKVIREIVATTGAKVDIDDEGLIKISSSDLTQIEAAKNWILGIVEEAEVGKIYKGKVVNIVDFGAFVNFMGGKDGLVHVSEMKNERVEKPTDVVKEGQDVYVKVLEIDQRGKVRLSMRVVDQETGAELEDTRPPREPREPRGDRGDRGDRGDRRGPRGDRGPRREGGDRGPRREGGDRPRRDRDDGPAPDHMPAFLKSDD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM39_YEAS6
Sequence: MWGLCKNHFPSNKIQVQERNKALKPKKSGSEHKTKQLFPVFNCKKKEKGVMIRFAILRNANTSLLSARSICLFTQAPTYCHVRLNTLNKSITTKRNSLTESKRHVHDGKHFFTTPHQQQQTKLGEIEEGHSPNIKGEDLRSIGQAITHQRNKRRKQIWSAIFGGIFGVILGYSLIYRVIYLKEQSFLPLFPSSKIRKLSTRDLKKVDVNQVQKLSKLRVLEILSGHDMIKEQYGVPLLDKDGNSPTLNEFSMWCEDQDPCVTGIVMEPDDKRDSSHTWYRIPFVCKWRITHRPISIRGTIDDLLNRIGLETADLFEIISPERVYGSFKYEYPLQGDSHALHLWFHGEIELDDDSLIVYNGKYHVDVKLQEIDLFRREKNGQLIQYVLYKNEAGDK
What are the official names of this protein?
Altered inheritance of mitochondria protein 39, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM39 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.