PharMolix/UniProtQA huggingface dataset:
Protein: GSA_NITSB
Sequence: MLSKSEAAYKEALRYIPGGVDSPVRAFKSVGGVPPFIDRGEGAFLYDIDGNRYIDYVQSWGPLIFGHADKETLEAVCEQAQKGLSFGTPTLLETELAREIVELFDNIDKIRFVSSGTEAVMSAIRLARGYTGRDDIVKFEGCYHGHSDSLLVSAGSGAATFGNPSSPGVPADFTKHTLLARYNDIESVKRCFQASDNIACVIIEPIAGNMGLVPAEEEFLQDLRKLCDEHGALLIFDEVMSGFRASLKGAQGFTSVVPDMVTFGKVIGGGMPVGAFGARAEIMAHLSPEGPVYQAGTLSGNPVAMVAGLSVIRRLKNDPSIYEVLEARAKGLVGGFKKIADSFGVPLQVDVRGSMFGFFFNEKPVKNFDDAKQSDLEFFAKFHQEMIKRGIYFACSQFEAGFICTPLDEKLIDETLEKIEEGLKKIV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_STRPC
Sequence: MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKERKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQMKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVEQGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTEWSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDVTVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFARHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAYNNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYHPELQSRPNRPEELYTAFVTAAIKNSN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: AAGAB_PONAB
Sequence: MAAGVPCALVTSCSSAFSGDQLVQHILGTEDLIVELTSNDAVRFYPWTIDNKYYSADINLCVVPNKFLVTAEIAESVQAFVVYFDGTQKSGLDSVSSWLPLAEAWLPEVMILVCDRVSEDGINRQKAQEWCIKHGFELVELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGSADPCHPEQPHLPAADRTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDVENFERLFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDEEH
What is the function of this protein?
May be involved in endocytic recycling of growth factor receptors such as EGFR.
What are the official names of this protein?
Alpha- and gamma-adaptin-binding protein p34.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: XPOT_EMENI
Sequence: MEEQVANAIEIAGNPTSDSTLKAQAFDYLNQLRTDPSGWQVCLSLFTKDPPQSHFIRHVSLEVVNSAAQAGLIDLRSLGFVRDRLLAYLRQVYGREGSNPDPPNIQNKIAQTITFLFSALYGNGWESFFDDLLSLTHKSPSSTTRDNPLGIIFYLRVINSIHDEIGDVLVSRSRAEQERANALKDLIRVRDMQKIASSWQEILSQWMDGDDLIVEMSLKAVGSWVSWIDIGLVVNQTMLDLLFQQLGRAQKAELREGEDKVRDAAVDVFTEIIGKKMKAEDKIDMIAFLNLDNVVGQISSSPPLYANRFTSKYDTDLAETVAKLVNTTVTDIVRALEQETVSAQCKEKANGLLQVFLPHILRYFSDEYDEVCSTVIPCVSDLLSYLRKMAKSNPSIASQHSSILLPILKAIIQKMRYDETASWGDDDDQTDEAEFQELRKRLGTLQQIVAAVDERLYMEAVSEVVATTFENMRQSGAQLDWRDLDLALHEMYLFGDSATKSGSLYNKGQPSGPSAERLVEMMLRMVESDIRSFTHPATQLQYMEICVRYSSFFHTHTHLIPGVLESFLQLAHHPMKKVKTRAWYLFQRLVKQLRAYIDNVAQTVVEALGDLLVIQAELPSESSDGDEMSSEDHEGSTDAVFNSQLYLFEAVGIICSIPTIPADKQVLYAQSVLSPVFVDMEKNLGSAKSGDARAVLQIHHDIMALGTLARGFSDWQPGTSSPATQLPAPEVSEAFSQVSEATLVALESLKASFDIRTASRFAFSRLIGVLGSRILPQLPRWIDGLLTQTSSRDEMALFLRLLDQVIFGFKGEIYNILDALLMPFLQRVFSGIADPTSGTDDEIHLAELKREYLNFLLAVLNNDLGAVIISERNQPMFDTVITTIEHFAKDAEDFTTAKMAFSVLSRMGSAWGGPDIAPAASNGPSTSQVALPGFGQFMITRFSPLCWALPATPSFNAKDAQAKQVLAEAGGLQRTIYSKMGMEYIEYLRDRELPGMGMGADLVEEYVGTLSRLDLRGFRQFFPQFIQRLSA
What is the function of this protein?
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.  Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).
What are the official names of this protein?
Exportin-T, Exportin(tRNA), Karyopherin-beta, tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: GLYA_STRA3
Sequence: MIFDKDNFKEFDQELWQAIHDEEIRQQNNIELIASENVVSKAVMAAQGSVLTNKYAEGYPSHRYYGGTDCVDVVESLAIERAKTLFNAEFANVQPHSGSQANAAAYMALIEPGDTVLGMDLAAGGHLTHGASVSFSGKTYHFVSYSVDPKTEMLDYDNILKIAQETQPKLIVAGASAYSRIIDFEKFRQIADAVDAYLMVDMAHIAGLVASGHHPSPIPYAHVTTTTTHKTLRGPRGGLILTNDEAIAKKINSAVFPGLQGGPLEHVIAAKAVALKEALDPSFKIYGEDIIKNAQAMAKVFKEDDDFHLISDGTDNHLFLVDVTKVIENGKKAQNVLEEVNITLNKNSIPFERLSPFKTSGIRIGTPAITSRGMGVEESRRIAELMIKALKNHENQDILTEVRQEIKSLTDAFPLYEN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOVD_ASPTN
Sequence: MGSIIDAAAAADPVVLMETAFRKAVKSRQIPGAVIMARDCSGNLNYTRCFGARTVRRDECNQLPPLQVDTPCRLASATKLLTTIMALQCMERGLVDLDETVDRLLPDLSAMPVLEGFDDAGNARLRERRGKITLRHLLTHTSGLSYVFLHPLLREYMAQGHLQSAEKFGIQSRLAPPAVNDPGAEWIYGANLDWAGKLVERATGLDLEQYLQENICAPLGITDMTFKLQQRPDMLARRADQTHRNSADGRLRYDDSVYFRADGEECFGGQGVFSGPGSYMKVLHSLLKRDGLLLQPQTVDMMFQPALEPRLEEQMNQHMDASPHINYGGPMPMVLRRSFGLGGIIALEDLDGEDWRRKGSLTFGGGPNIVWQIDPKAGLCTLAFFQLEPWNDPVCRDLTRTFEHAIYAQYQQG
What is the function of this protein?
Monacolin J acid methylbutanoyltransferase; part of the gene cluster that mediates the biosynthesis of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR) (PubMed:10334994, PubMed:12929390, PubMed:21495633).  The first step in the biosynthesis of lovastatin is the production of dihydromonacolin L acid by the lovastatin nonaketide synthase lovB and the trans-acting enoyl reductase lovC via condensation of one acetyl-CoA unit and 8 malonyl-CoA units (PubMed:10334994, PubMed:10381407, PubMed:19900898, PubMed:22733743).  Dihydromonacolin L acid is released from lovB by the thioesterase lovG (PubMed:23653178).  Next, dihydromonacolin L acid is oxidized by the dihydromonacolin L monooxygenase lovA twice to form monacolin J acid (PubMed:12929390, PubMed:21495633).  The 2-methylbutyrate moiety of lovastatin is synthesized by the lovastatin diketide synthase lovF via condensation of one acetyl-CoA unit and one malonyl-CoA unit (PubMed:19530726, PubMed:21069965).  Finally, the covalent attachment of this moiety to monacolin J acid is catalyzed by the transesterase lovD to yield lovastatin (PubMed:10334994, PubMed:17113998, PubMed:18988191, PubMed:19875080, PubMed:24727900).  LovD has broad substrate specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptopropionate (DMB-S-MMP) as the thioester acyl donor, and can also catalyze the reverse reaction and function as hydrolase in vitro (PubMed:19875080).  LovD has much higher activity with LovF-bound 2-methylbutanoate than with free diketide substrates (PubMed:21069965).
What are the official names of this protein?
Monacolin J acid methylbutanoyltransferase, Lovastatin biosynthesis cluster protein D, Lovastatin hydrolase, Simvastatin synthase LovD, SV synthase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: MELB_SALTY
Sequence: MSISLTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLVGTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLTNSLVLFLLFSAHLFEGTAQVVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPFPRFFASLAGFVTAGITLPFVSYVGGADRGFGFQMFTLVLIAFFIASTIVTLRNVHEVYSSDNGVTAGRPHLTLKTIVGLIYKNDQLSCLLGMALAYNIASNIINGFAIYYFTYVIGDADLFPYYLSYAGAANLLTLIVFPRLVKMLSRRILWAGASVMPVLSCAGLFAMALADIHNAALIVAAGIFLNIGTALFWVLQVIMVADTVDYGEFKLNIRCESIAYSVQTMVVKGGSAFAAFFIALVLGLIGYTPNVAQSAQTLQGMQFIMIVLPVLFFMMTLVLYFRYYRLNGDMLRKIQIHLLDKYRKTPPFVEQPDSPAISVVATSDVKA
What is the function of this protein?
Mediates the transport of melibiose and other galactosides by a symport mechanism (PubMed:21148559, PubMed:24389923, PubMed:29054867, PubMed:34110360).  Can use sodium, lithium and protons as coupling cations, with a preference for sodium and lithium (PubMed:21148559, PubMed:24389923, PubMed:29054867).  The use of Na(+) as coupling ion for sugar transport is based not on ion selectivity but on competitive binding under physiological conditions, because of a much higher Na(+) concentration under physiological conditions (PubMed:29054867).
What are the official names of this protein?
Melibiose permease, Melibiose carrier, Melibiose transporter, Melibiose/cation symporter, Na+ (Li+)/melibiose symporter, Thiomethylgalactoside permease II.
What is the protein family that this protein belongs to?
Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TSE5_PSEAE
Sequence: MSGLPVSHVGEKVSGGVISTGSPTVHVGSSAVGLADRVSACVPLVGKPVNPMLGSKLLPEEVDFALAAPDTFTFARGYLSSNPRIGRLGRGWWLPGESMHLELSEDACVLVDAQGRRIGFPALAPGAQHYSGSEELWLRRGGSSGGEAQAWRGRWAAVPAELQTQEGSVLVLSGHSYLHFQRCPDGIWRLQASFGRAGYRTEFRWSGRGLLTGVRDSAGRSYALVYQQACEPSEGDDGLRLFGVILASHDGPPPDYIDPQSPGLDWLVRYQFSDSGDLIAVRDRLGQVVRVFAWREHMLVAHGEPGGLEVRYEWDVHAPHGRVVKQIEAGGLTRTFRYLRDATEVSDSLGRVERYEFAGEGGQRRWTALVRADGSRSEFDYDLFGRLVAMRDPLGRETRRRRDGQGRMLEEESPGKARYRKRVDEETGLLVELEDAMQRRWTFERDERGNATTVRGPAGSTRYAYEDPRLPDRPTRIVDPRGGERRLEWNRFGLLAALTDCSGQVWRYDYDNEGRLVASSDPLGQLTRRRYDPLGQLIGLELADGSALSYEYDALGRQTRIADAEGHATLFSWGHGDLLARVSDAGGGELSYLHDEAGRLVALTNENGVQAQFRYDLLDRLVEETGFDGRRQRYRYNAADELIAREDADGRETTYAYDRDGRLASIRVPATEHAPALVERYRWLADGRLASAGGADCEVRYTYDEVGNLRLESQVHADGWVYSVEHSHDALGVRQTSRYGDAPPVAWLTYGPGHLHGALVGAVELAFERDALHREVRRDARRDGQDDALFTQERQHAPLGRLQRSRLRLAGGFDWQRGYRYDGLGQLVGIDDNQYPSVRYEYDLGGRLLASRRAGAAASTYRYDAAGNRLEGVGEHAREDARQAFAENELYRSGFSRSETRASQAGEGPARWAGNRVERIAGNRYRFDALGNLVERIGADGERLRLAYDGAQRLVHLTRDYADGTRLEARYRYDALSRRIAKVVLRDGVEQQVRFGWDGDRQCAEAFARELRTTVHEPGGFVPLLRLEQACEPDPPELLQLRQAFAAEGQPLPAQCVPALGEARIAFFHTDHLGTPLQLSDERGQLRWQGVPDDWRAVAPERQPGAQPIRFQGQYHDEESGLYYNRYRYYLPEAGRYASQDPLGLGGGPNPYAYALNAPTLAYDPTGLIIPLVVIGAFAARAAIGAALGAGIELGMQTGKQVLGQMKDNWDSDRDLTDIKWKCIDINWKHVGASAAIGTVAPGMLSTGKTVVQSAKAIRTLSGQAANTANRAAKLAARKAAHADTIKKAVATQAAWQTGKQIVKCPLKDEEEECPPQ
What is the function of this protein?
Toxin secreted by the H1 type VI (H1-T6SS) secretion system that acts on bacterial target cells.  The producing bacterium is protected by a cognate immunity protein.
What are the official names of this protein?
Toxin protein Tse5.
Protein: PER2_HORVU
Sequence: STLISSFANRSLDVADLVSLSGAHTFGVAHCPAFEDRSSRVRHNPAIDGKFATALRNKCSGDNPSGTLTQKLDVRTPDVFDNKYYFDLIARQGLFKSDQGLIDHPTTKRMATRFSLNQGAFFEQFARSMTKMSNMDILTGTKGEIRNNCAVPNRRVRTSRPPSPARGDRR
What is the function of this protein?
Involved in defense response to powdery meldew fungus.
What are the official names of this protein?
Peroxidase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
Protein: PSBN_BASHY
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ATP6_OCEIH
Sequence: MDHENPIVHDIFGIPGANLNLSNLMMTFIVCLIVFVFCVWGSRKLQMKPKGIQNFMEWAVEFVRGIIQDNMDWKTGRIFLPLGLTLIFYILVSNLIGVATVGVVEHDLWWKSPTADAVMTLTLSTMIIALTHYYGIKLRGTKAYLKTYVSPVPLMLPFKIVEEFTNTLTLGLRLFGNIYAGEILLSLLVGLATTSIFGFFGAALPMLAWQTFSVFIGAIQSYVFVMLTMVYMSHKVSSDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LCK5_RHYMA
Sequence: GSGFSSWG
What is the function of this protein?
This cephalomyotropic peptide stimulates contractile activity of cockroach protodeum (hindgut).
What are the official names of this protein?
Leucokinin-5, Leucokinin V, L-V.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPF_FRATW
Sequence: MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDEKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: AROQ_DESAP
Sequence: MRVLVLHGPNLNLLGRRETGIYGNETLADIDARLQELASELGVDLECFQSNSEAALIERLHGAPGTVDAVVFNPAGFTHYSIALRDAVAAVGLPVVEVHLTNIHAREEFRHRSVIAPVAAGQISGFGTAGYLLGLRAAVELVSRGKMSRA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: MEP3_TRIEQ
Sequence: MHGLLLAGLLALPMNVLAHPAEQHASNVLSRRGVDIESFRLPLKAKYMDSDAAAQKIQAMSFSKDDDYVSTATKLVKSTFPKSTFRVVDDHYTGTNGIGHVHFKQTAHGLDIDNSDFNVNIDRDGKVFSFGNSFFTGEIPKENPMVKRAFSDPVKALKGAVKALNLPVKSDNAKAKTTAGKESFEFMGTTGALSAPKANLVYLQKEDGTLALTWRVETDVGDNWLLTYVDAHNSETVHNVVDYVASAEFKVFAWGLNDPTEGNPTSIRDPWTDSSPYTWHSDGMTKYPTTRGNNAIAQDNPTGGSTYINNYRPQSPNLIFNYPWSPTATPPSSYKDFSITQLFYTTNRFHDLLYSFGFNEAAGNFQVNNGNKGGRGNDFAIVNAQDGSGTNNANFATPPDGSPGRMRMYNWTTARPNRDGCLEAGIVIHEYAHGLSNRLCGGPANSGCLNALESGGMGEGWGDFYATAIRLKPRDTKDTNYSMGAWAANNPKGIRAYLYSTNLQTNPYMYTSVNSLREVHQIGTVWATMLYDLMWALIEAHGGTYSANPVFRNGVPQDGRHLAMKLVMDGMALQPCNPNFVQARDAILDADRALTNSANKCTIWKAFAKRGLGYGAKYDARNRTGSNRLPPGC
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 3, Fungalysin MEP3.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_RICPR
Sequence: MSNIDKERAIAAALAQIEKSYGKGSVMKLGQRPNVDIEAISTGSLGLDIALGIGGVPKGRIIEIFGPESSGKTTLTLHLIAESQKKGGTCAFIDAEHALDPAYAKKLGVNIDELIISQPDTGEQALEIADTLIRSGGIDMIIIDSVAALVPKSEIEGEMGDAQMASQARLMSQALRKLTASINRTNCITVFINQIRMKIGVMFGSPETTTGGNALKFYASVRIDIRRIGSIKDKEEVIGSQTKVKVVKNKVSPPFKTADFDIMYGSGISKEGEIIDLGVKLEIIEKSGSWFSYNKIRIGQGRENVKQYLKEHPQISNEIEKIIREKSSAITNINLDQTEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_VIBVY
Sequence: MEAIINKLYLQESLTEQESQQLFDTIIRGELDPILMASALTALKIKGETPDEIAGAAKALLANAQPFPRPDYDFADIVGTGGDGHNTINISTTAAFVAAACGLKVAKHGNRSVSSKSGSSDLLDSFGINLAMSAEDTRSAVDSIGVAFLFAPQYHSGVKHAMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSQELVRPIAETMLKMGMKRAAVVHGSGLDEVAIHGDTLVAEIKDGVIHEYTLTPADFGVNTHPLEAIKGGDPEENKAIITHLLTGKGTEAQLSAVAVNVALLMRLFGHEDLKANTQQAIDVMNSGKAYQLVEKLAQHA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: BUK_PHOV8
Sequence: MKIFVINPGSTSTKIALFIDEKPVWAAGAHHTADDLSEFHHVNEQYAYRKDFVLRLLAEADIPLDFDAVIARGGLLKPTPGGVYAINEQMKHDLLNARMEHACNLGALIADEIARECHCPAYIADPEVVDELQPAARLTGIPEIERISIFHALNSKAVSRKYAASIGKHYEELNLIVVHLGGGISVGAHCKGRVIDVNNALNGEGPFSPERAGTIPADQLAELCFSGKYTLKQIKKMLNGKGGLTAHLGMNDVVTIARKASEGEEPYKGVLDAMLYTVAKQAGAMYVTLRGQVDAIILTGGIAHSDYCVGILKEQIDYLAPVVLMPGEDEMGSLAYNALGALKGELPLQVYRPE
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSX1_CALJA
Sequence: MAPSADMTSLPLGVKVEDSAFGKPAGGGSGQAPGAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESSLAASESAQAAGGLAQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
What is the function of this protein?
Acts as a transcriptional repressor.  May play a role in limb-pattern formation.  Acts in cranofacial development and specifically in odontogenesis (By similarity).
What are the official names of this protein?
Homeobox protein MSX-1, Msh homeobox 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMA_SALDC
Sequence: MNNRVHQGHLARKRFGQNFLNDRFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDKLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELSAQLGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPYPVKDIRVLSRITTEAFNQRRKTIRNSLGNLFSVETLTEMGIDPAMRAENISVAQYCQMANYLSENAPLKES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBBP9_MOUSE
Sequence: MASPNKAVIVPGNGGGDVATHGWYGWVKKGLEQIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHQVYALVLVSAYTSDLGDENERASGYFSRPWQWEKIKANCPHIVQFGSTDDPFLPWKEQQEVADRLDAKLYKFTDRGHFQNTEFHELISVVKSMLKGPE
What is the function of this protein?
Serine hydrolase whose substrates have not been identified yet.  May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation.  May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1.
What are the official names of this protein?
Putative hydrolase RBBP9, B5T-overexpressed gene protein, Protein BOG, Retinoblastoma-binding protein 9, RBBP-9.
What is the protein family that this protein belongs to?
Belongs to the RBBP9 family.
Protein: DSG1_BOVIN
Sequence: MNWPFFRAAVVLFIFLVVLEVNSDFRIQVRDYNTKNGTIKWHSLRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSLGQDLEKPLELRVRVLDINDNPPVFSMSTFVGEIEENSNANTLVMVLNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRYTGEIRTMNNFLDREQYGQYSLAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMELPTQSISIEENSLNSNLLQIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDFEAMNNLQLSLGVRNKAEFHQSIMSQYKLTATAISVTVLNVVEGSVFRPGSKTFVVNSNMGQNYKIGEYVAWDLDANRPSTTVRYVMGRNPTDLLAIDSKTAIITLRNKVTMEQYKILGGKYQGTILSIDDALQRTCTGTIVINLENGGWKTERPNVNGSTTSAYGLTSGGVTTNGYTTGGGVGTVTFAVGTNGYGVGTGVYQPLRDNVHFGPAGIGLLIMGFLVLGLVPFLLMCCDCGGAPGGGAAFEPVPECSDGAIHSWAVEGAQADPGVLANSAVPCIPVTNANVIEYVDNSGVYTNEYGAREMQDLGGGERTTGFELTDGVKMSGGPEICQEYPGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGAGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKDVEPFPDSDPSWPPKSTEPVCPPQGTEPTGGGHPPISPRFGTTTVISENTYPSGPGVQHPTPIPDPLGYGNVTVTESYTSSGTLKPSVHIHDNRHASNVVVTERVVGPISGADLQGMLEMPDLRDGSNVIVTERVIAPSSSLPTTLTIPDPRQSSNVVVTERVIQPTSGIVGNLSMHPELSNTHNVIVTERVVSGSGITGSSSLLGSAGGGSGGGIGLGSLGGGGGLSSSLGGAATIGHLRGSAEHHFSNTLGSASPTTTRSRITKYSTVQYTK
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
What are the official names of this protein?
Desmoglein-1, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: RL17_MARMS
Sequence: MRHRKSGRHLNRTSSHRKAMFKNMAASLFEHEVIKTTLPKAKELRRVAEPLITLAKVDSVANRRLAFARTRSKDAVGKLFSELGPRYQARPGGYVRILKCGFRSGDNAPMAYVELVDRPVAEAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RABL6_BOVIN
Sequence: MFSALKKLVGSEQAPGRDRNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALWHRLQGKKFVEEYIPTQEIQVTSIHWSYKTTDDVVKVEVWDVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDVLDHLDRPPGSSYFRYAESSMKNSFGLKYLHRFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYDIFLEMMEARSRGHASPLTTSGQSPSSGSQSPVVPPSTVSTGSSSPSTPQPVLQPPLQAPPAPPAPAEAPPLPAAPPRRSIIARLFGSTPATEAAPPPPEPTPAAEASQKVQNVEDFVPEDSLDGSFLEDTVPAKDEKRLGARGPQDSDSDRETQAGNPMVAGFQDDVDLEDKPPSRPLPPTGPVPSEDITLSSEEEAEEGAGHPKAAVLAPQKCPEPETRRSSTKALGPPRDAAPRAAKPRPEGPSGKLEEGTDKPVSSESDAEGPIAAQMLSFVMDDPDFESDSDAQRRAGEFPVREDLSDLTDEDAGPVQPPAPPKPLAPSFRLKDDSDLFGLGLEEPGREDSSEQDKEGRPPAKEKKKKKKKGREEEDKAAKKRSKHKKSRERADDKGRDERRRRPRGPQRTALDELEAFLGGGAPSGPLRGGGDYEAL
What is the function of this protein?
May enhance cellular proliferation.  May reduce growth inhibitory activity of CDKN2A (By similarity).
What are the official names of this protein?
Rab-like protein 6, GTP-binding protein Parf, Rab-like protein 1, RBEL1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly cytoplasmic.
Protein: RNM52_LIGS5
Sequence: MINRIKISQVIVAEGRDDTTNLKRYFDVETYETRWSAINDQDIERIQRLHELHGVIVFTDPDFNDERIRRMIITVIPTVQHVFLKRDEAVPKSKTKGRSLGIEHASYEDLKTALAQVTEQFKNENEFDISRSDLIRLGFLAGADSRKRREYLGEQLRIGYSNGKQLLKRLELFGVTLAEVKEAMTKYSI
What is the function of this protein?
Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor.  Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
What are the official names of this protein?
Ribonuclease M5 2, RNase M5 2, Ribosomal RNA terminal maturase M5 2.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease M5 family.
What are the subcellular locations of this protein?
Cytoplasm.