PharMolix/UniProtQA huggingface dataset:
Protein: 2A5D_YEAST
Sequence: MMRGFKQRLIKKTTGSSSSSSSKKKDKEKEKEKSSTTSSTSKKPASASSSSHGTTHSSASSTGSKSTTEKGKQSGSVPSQGKHHSSSTSKTKTATTPSSSSSSSRSSSVSRSGSSSTKKTSSRKGQEQSKQSQQPSQSQKQGSSSSSAAIMNPTPVLTVTKDDKSTSGEDHAHPTLLGAVSAVPSSPISNASGTAVSSDVENGNSNNNNMNINTSNTQDANHASSQSIDIPRSSHSFERLPTPTKLNPDTDLELIKTPQRHSSSRFEPSRYTPLTKLPNFNEVSPEERIPLFIAKVDQCNTMFDFNDPSFDIQGKEIKRSTLDELIEFLVTNRFTYTNEMYAHVVNMFKINLFRPIPPPVNPVGDIYDPDEDEPVNELAWPHMQAVYEFFLRFVESPDFNHQIAKQYIDQDFILKLLELFDSEDIRERDCLKTTLHRIYGKFLSLRSFIRRSMNNIFLQFIYETEKFNGVAELLEILGSIINGFALPLKEEHKVFLVRILIPLHKVRCLSLYHPQLAYCIVQFLEKDPLLTEEVVMGLLRYWPKINSTKEIMFLNEIEDIFEVIEPLEFIKVEVPLFVQLAKCISSPHFQVAEKVLSYWNNEYFLNLCIENAEVILPIIFPALYELTSQLELDTANGEDSISDPYMLVEQAINSGSWNRAIHAMAFKALKIFLETNPVLYENCNALYLSSVKETQQRKVQREENWSKLEEYVKNLRINNDKDQYTIKNPELRNSFNTASENNTLNEENENDCDSEIQ
What is the function of this protein?
Multicopy suppressor of ROX3 and HSP60.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, PP2A, B subunit, B' delta isoform, Protein RTS1, Protein SCS1.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MATK_ASPLU
Sequence: MEELQGYLEKDRSGQQHFLYPLLFQEYIYALAHDHGLNSSIFYEPVEIFGYDNKSSLALVKRLITRIYQQNFLISSVNDSNQNRFLEHNRFFYSQFYSQIISESVAIYVEIPFSRRLVSFFXEKEIPKYHNLRSIHSIFPFLEDKLSHLNYVSEILIPXPXHIGILGQILQCQIQDVPFLHLLRFFLDEYHNWNSLFITQNKSIYVFSKENKRLFRLLYNSYVFECEFFLLFFRKQSYYLRLTSSEIFLERTHFYRKIEQLRIELEHFVVVCRNYFHRTLWFLKNPFMHYVRYQRKAILASRGTHFLMKKWKYYFVNFWQYYFHFWSRPYRININHLSNYSFYFLGYFSSLLKNSLAVRNQMLENSFLIDTITKKFDTRVPVILLIGSLSKAKFCTVSGHPISKPIWADLSDSDIIDRFGRICRNLSHYHSGSSKKQDLYRIKYILRLSCARTLARKHKSTVRTFLRRLGSGLLEEFFTEEEQVLSLIFSKTTPFTLHGXHRARIWYLDIIRINDLVNHSXLS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y4EN_SINFN
Sequence: MKFLIDECLSPELAKMAIEKGHGETSHVVWMKLGGLKDWELKPIILEGDWTFVTKNSVDFRGPKDKPGTKGQYADVAIHAGLICLNGHPAWTSTCRSSCLSRR
What are the official names of this protein?
Uncharacterized protein y4eN.
Protein: Y1534_SYNY3
Sequence: MSSLPKNFLQPLPLQPGDRLTVVSPSGSLRELADLQKGVDIWRSWGYEVIFSQGYHNRFGYLAGTDQQRRQDLLHAWLDPQCKGILCSRGGYGSARLLEDWQWPAISQPKWVLGFSDVTGILWSLLKSGIISLHGPVLTTLSDEPDWALERLRGHLQGLPLAPLTGNSWQKGMARGRLVAGNLTVATHFLGTEWQPDFENVILAIEDVTESPYRIDRMVTQWRASGNLSQVAGIALGRFSECEAPAGFPSWTVEEVLGDRLGDLGIPVVADLPFGHGGVNAILPVGSKAELDGDAGTLSFL
What are the official names of this protein?
Putative carboxypeptidase slr1534.
What is the protein family that this protein belongs to?
Belongs to the peptidase S66 family.
Protein: ILVC_CHRSD
Sequence: MRVYYDKDCDLSLIQAKNVTIVGYGSQGHAHAHNLKESGVDVTVALRPGSSSVAKAEAAGFKVASVPDACKTADVLMLLAPDENQKAIYEQDIAPNLKQGATLAFAHGFNIHYNQVTPRADLDVIMIAPKAPGHTVRSEFVRGAGVPDLIAVQQDATGQAKELALSYAAGVGGGRSGIIETTFKDETETDLFGEQAVLCGGAVELVKAGFETLTEAGYEPEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPEVINEQSREAMRNALKRIQNGEYAKMFISEGNSNYPSMHARRRLNAEHPVEQVGEKLRGMMPWIAANQLVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CISY_BARTA
Sequence: TYIDGNKGILLYRGYPIDQLAERGDFLESCYLLLYGELPTKQEKHDFDRCIMQHTMVHEQFARFFHGFRRDSHPMAVMVACLGAMSAFYHDSIDITDPQQRMIASVRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANFLRMCFSVPCEGYNINSVLTRAMDRIFTLHADHEQNASTSTVRLAGSSGANPFACIAAGVACLWGPAHGGANEACLKMLQEIGSVERIPEFIARAKDKNDPFHLMGFGHRVYKNYDPRAKIMQKTCHEVLKELNIQDDPLLDIAMELEKIALNDEYFVEKKLYPNVDFYSGITLKALGFPTE
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: DAPD_PASMU
Sequence: MSLQHIIEAAFEKRAEITPKTVDAQTRAAIEEAIEGLDSGKYRVAEKIDGEWVTHQWLKKAVLLSFRINDNELVAGSETNYYDKVPMKFAEYDAARFQQEGFRVVPPAAVRKGAYIAKNTVLMPSYVNIGARVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIYDRETGEVTYGRVPAGSVVVSGSLPSKCGKYSLYCAVIVKKVDAKTLGKVGINELLRTIDE
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_GRVMC
Sequence: MATIRHIMDWLRPTFTPLAGVKSRQECIAHYGDDWALMITQSRMTLSAEAQVNAWYEGGAEVNGSIPSVEGNAAAPQAAAVVAEPPHPSPAENEGEDASWVAALPAPPTYEVVQGRAPTLEEIHGASRLQIVPYTGRARVIGEDEVLPSPVLSSIWRATRCPGRILRVLGTLLKPGACQRHLEDLREVQPQVCVGNPCEVKLQEEGAPMAYMNAQSIAMELRAMFGWQAATPANRELGNRVARDILRDGCGATREQIWYMSSLALHMWFQPTLCDLAIKAGAQNFLVGEVYARSGVETKTRPKILSPQIKVKLAARPRPVKRVSYNVDVLGPSADYGVHNNSLNNLVRGVNERVFYTNNQGKLPLAPAAGAYQQIDCAALKQFRVTPWSLDDVWMSYKGSQRVRYKQAVDSLGMRPLSKSDARVSTFIKAEKVNFRAKPDPAPRVIQPRDPRFNAVFAKYIKPLEPLLYKALGKLYKYPCVAKGFNAVETGEIVAKKWKMFANPVCVGLDASRFDQHVSVDALRFTHGVYRRFVKSSEFDKLLRWMYTNRCRGAAKDGFVKYTVNGCRMSGDMDTALGNCVLMVLMTRHLLMSLGIPHELLDNGDDCIVIMDQEHLAKFNDAVKPYYSNLGFTMKVEEPVYSLERVDFCQTRPVYDGKKWRMVRHITSVAKDCCTVINWEQLPSWLSAIGECGIAVAGGIPVHNSFLRYLMRVGGTKGGIENHLLWKNEGLSWYRMGMDLSHEKVVSDEARLSFQTAFGISPTMQRALEDLYDGLGAPTVNGCDYRTVKTRDCREIECMPPRHYNHYFIDCGMQPAGSQEQYVNPGYTIFEAAALWAQC
What is the function of this protein?
RNA-dependent RNA polymerase replicates the viral genome.
What are the official names of this protein?
RNA-directed RNA polymerase, RdRp.
Protein: PGAM5_RAT
Sequence: MAFRQALQLAACGLAGGSAAVLFSAVAVGKPRAGGDADTRTTEPLAWTGARPGHGVWDSNWDRREPLSLINLKKRNVEFGEDELASRLDHYKAKATRHIFLIRHSQYNVDGSMEKDRTLTPLGREQAELTGIRLASLGLKFNKIVHSSMTRAVETTDIISKHLPGVCRVSTDLLREGAPIEPDPPVSHWKPEAVQYYEDGARIEAAFRNYIHRADAKQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRLSLNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS
What is the function of this protein?
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase.  Has apparently no phosphoglycerate mutase activity.  May be regulator of mitochondrial dynamics.  Substrate for a KEAP1-dependent ubiquitin ligase complex.  Contributes to the repression of NFE2L2-dependent gene expression (By similarity).  Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
What are the official names of this protein?
Serine/threonine-protein phosphatase PGAM5, mitochondrial, Phosphoglycerate mutase family member 5.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: DEF_BAUCH
Sequence: MSLLPILYYPDHRLRQISKPVNKINNSIYRIVYDMFDTMYHKNGIGLAAPQVNINLNIIVIDVSENKEQRLVLINPELLAKSGETGIHEGCLSIPEQHGFVPRAKNIKVRALDLNGNSFNLETNDLQAICIQHEMDHLVGKLFIDYLSPLKRQRLLKKMKQLIRNLD
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: UVRC_THEFY
Sequence: MTVRPTLRPKPGSIPTDPGVYRFRDEHGRVIYVGKAKNLRARLSSYFQDFSALHPRTQTMISTAADVDWTVVNTEVEALQLEYSWIKEYSPRFNVRYRDDKSYPYLAVTLNEEFPRVQVMRGARRRGVRYFGPYSYAWAIRDTVDLLLRVFPVRTCSAGVFKRARSSGRPCLLGYIDKCSAPCVGRIGVEEYRALAEDFCAFMAGETGRFLRQLEAEMKQAAAAQEYERAARIRDDIQALRTVMEKQAVVLGDSTDCDVIAIAEDQLEAAVQVFYVRGGRIRGERGWVVDKVEDVSTGKLVEQFLAQTYGGADDEESTTAIPREVLVSAEPADRDAVVAWLSKRRGAAVDVRVPQRGDKRALMETVLKNAEQTLARHKSQRASDLTTRSKALAEIAEALGLAEAPLRIECFDISTLQGEHTVASMVVFEDGLARKSEYRRFSIRGAEGADSDVAAMYEVISRRFTRYLEESQRVGELDTLGESGAPQGAERKAPRFAYPPNLVVVDGGRPQVAAAQRALDDLGIEDVAVCGLAKRLEEVWLPGEEDPIILPRTSEGLYLLQRVRDEAHRFAISYHRRKRAKALTASVLDDIPGLGPVRRAALLKHFGSVRRLAQATAAEIAEVPGIGERTAQTIYERLTSVEGGQRTQPENSKADE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF369_IIV3
Sequence: MGIKNLTQFLKKYKVYETIDVAELKYSKICIDTPMFLYKFVSQYPNSNEWLGCFVTLITWLRKWNIHPTFVFEGKAPPEKNQTQEARKESRQKIVSKTDAIEQDLRTYLKSGTITPLLLDTWQKIRSKSTKSLLVKRPLNLIVKNFINVDEIRLEIDRRRKYEFSITFAHVNLLKELLDLMGVGYIQSKGEAEADCVSLWYNNAVDYIVSEDTDVLAYTFAGGAPGTSTPKKVPNTTDLKVITGFNVGESSATIISKQRVLSTLKMTAESFKDFCIMCGTDYNKNIFRVGVEKAYKYISDYKVIENVPLDTSVLDHHNVRKIFRVKKSIKYADKVQWSKYPSDNFVEVLNTFIWTHAGGTVDSDHVFRVLTDPALDIVFE
What is the function of this protein?
Probable endonuclease.
What are the official names of this protein?
Probable RAD2-like endonuclease 076L.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PSMD5_HUMAN
Sequence: MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREKTTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDIVRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKVFEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIRCLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTAIANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLRLRTYLSEGPYYVKPVSTTAVEGAE
What is the function of this protein?
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC).  In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 5, 26S protease subunit S5 basic, 26S proteasome subunit S5B.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5B/HSM3 family.
Protein: SYP_STRPC
Sequence: MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLPLANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNSDFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPARTDLDRWVVLDKSIASMDDIPKEVLEEIKAELAAWMISGEDTIAYSTESSYAANLEMATNEYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVGNDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLTNAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFKLGTRYSDSMGATILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRYAWGVNFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLTAKGYDVLTDDRNERVGSKFSDSDLIGLPIRVTVGKKAAEGIVEIKIKATGASIEVNAENLIETLEILTKEH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_TERTT
Sequence: MAKEKFERSKPHVNVGTIGHVDHGKTTLTAALTRVCSEVWGGAAVAFDGIDNAPEEKERGITIATSHVEYDSPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCGATDGPMPQTREHILLSRQVGVPYIVVFLNKADLLAEDCGGVGTDEYNEMLELVEMELRELLDTYEFPGDDTPIIPGSALMALNGEDDNELGTSAVRKLVETLDEYIPEPERAIDQPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEIEIVGINATTKTTCTGVEMFRKLLDEGRAGENVGVLLRGTKRDEVERGQVLAKPGTITPHTVFQSEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGACELPEGVEMVMPGDNIQMTVTLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDD_AZOSB
Sequence: MIIVTGGAGFIGSNIVQGLNDRGITDILVVDDLRDGRKCLNLADADIRDYMDMDDFLARIQTGEDLGRVEAVFHEGACSSTTEWDGRFVMRVNYEYTKALLAWCTQRKIPLIYASSASVYGMGPTFREAREFEQPLNMYAYSKFLFDCHLRAQQGIESQVVGLRYFNVYGPREQHKGSMASVAYHFNNQLNESGRVRLFEGSDGYGPGEQRRDFIHVDDVVAVNLWLFDNPQVSGIYNLGTGRAQSFNDVARAAIKWFRAQGEDGGRERGGIDYIPFPDHLKGRYQSFTEADMGALRAAGYDRPFMDVETGVPAYLSWLASQDKR
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: VP33B_RAT
Sequence: MAFPHRLDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKLTLSSNEQLCFLVRPRIKTMRYIANLVNADKLAGRVRKYKIILSPQKFYACEMVLEEEGVYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRCTKMSYDLWRKLEEEEDSETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFSEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQASGDTLTAVENKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLDRRSWQGLDEVVRLLNCSDFAFTDMAKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAVTNSARLMEAMSEVKS
What is the function of this protein?
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.  Mediates phagolysosomal fusion in macrophages.  Proposed to be involved in endosomal maturation implicating VIPAS39.  In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity.  Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 33B, r-vps33b.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Recycling endosome. Note=Colocalizes in clusters with VIPAS39 at cytoplasmic organelles. Colocalizes with RAB11A and VIPAS39 on recycling endosomes. Colocalizes with AP-3, clathrin, Rab5 and Rab7b.
Protein: ARGP_SALAR
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVASKPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEQELESGELINLTPGLLQRRMLYWHRFAPESRMMRKVTDALLEYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: 3SIYL_DENAN
Sequence: MKTLLLTLVVVTIVCLDLGYTLTCVTGKSIGGISTEECAAGQKICFKKWTKMGPKLYDVSRGCTATCPKADEYGCVKCCKTDRCNK
What are the official names of this protein?
Synergistic-like venom protein.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Aminergic toxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YETS2_HUMAN
Sequence: MSGIKRTIKETDPDYEDVSVALPNKRHKAIENSARDAAVQKIETIIKEQFALEMKNKEHEIEVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGSKTCDTMVFNHPAIKKFLESPSRSSSPANQRAETPSANHSESDSLSQHNDFLSDKDNNSNMDIEERLSNNMEQRPSRNTGRDTSRITGSHKTEQRNADLTDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDCIYPQSSESDISDAPPSLPLTIPAPVKASSPIKQSHEPVPDTSVEKGFPASTEAERHTPFYALPSSLERTPTKMTTSQKVTFCSHGNSAFQPIASSCKIVPQSQVPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHVKQGTAGSVINNPYVIMDKQPGQVIGATTPSTGSPTNKISTASQVSQGTGSPVPKIHGSSFVTSTVKQEDSLFASMPPLCPIGSHPKVQSPKPITGGLGAFTKVIIKQEPGEAPHVPATGAASQSPLPQYVTVKGGHMIAVSPQKQVITPGEGIAQSAKVQPSKVVGVPVGSALPSTVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKAQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQTLKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTKTSGQQQVCVSQATVGTCKAATPTVVSATSLVPTPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQSFSTSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNYVIKIDHLETIQQLLTAVVKKIPLITAKSEDASCFSAKSVEQYYGWNIGKRRAAEWQRAMTMRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQIDSEPECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKFYLPPTPGSEFIGDVTQKIGITLQPVALHRNVYASVVEDMILKATEQLVNDILRQALAVGYQTASHNRIPKEITVSNIHQAICNIPFLDFLTNKHMGILNEDQ
What is the function of this protein?
Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (PubMed:18838386, PubMed:19103755, PubMed:27103431).  YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) (PubMed:27103431).  Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:27103431).
What are the official names of this protein?
YEATS domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ITF2_CANLF
Sequence: MFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQSLLGGDMDMGTPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGSSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGAHREDGVALRGSHSLVPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM
What is the function of this protein?
Transcription factor that binds to the immunoglobulin enhancer Mu-E5/KE5-motif.  Involved in the initiation of neuronal differentiation.  Activates transcription by binding to the E box (5'-CANNTG-3') (By similarity).  Binds to the thyroglobulin promoter.
What are the official names of this protein?
Transcription factor 4, TCF-4, Immunoglobulin transcription factor 2, ITF-2, Thyroglobulin promoter transcription factor TFE.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROE_CHRSD
Sequence: MSDDRYCVFGNPVAHSRSPRIHALFAEQCGQAMTYEAIEAPREDFAGAWHAFVAAGGCGANVTVPFKEDAFRLADVLSQRARRAGAVNTLVRGRDGRTYADTTDGVGLVRDLEAHGVTLEGARILILGAGGAVRGVLDPLLAKAPSCLHIANRTASKAVRLAEEASPEGRVTGGGYSELDGAFDVVINGTSASLGGELPPLPDTLLAADGVAYDMMYAAEPTVFLQWAAAHGGRGIDGLGMLIEQAAESFFLWRQVRPDTAPVRETLRREL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RS14_BORBR
Sequence: MAKLSLINRDIKRAKLADKYAAKRAELKAIIDDQSKTDEERYQARLKLQQLPRNANPTRQRNRCVVTGRPRGVFRKFGLTRHKLREMAMKGEVPGMTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RIMP_GLOC7
Sequence: MTHPLIPQIIDLATPIAEKLGLEIVEVVFQTNKRPPVLRLDIRNLSSDTGLDDCEQMSRSLEATLDATELIPGSYVLEISSPGISRQLTSDREFIAFKGFEVIVKTYTPYENQKEWRGNLQGRDEQAVYLNKKGRAIAIPRQLVAKVQLNDQRTT
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M6B_STRPY
Sequence: MAKNNTNRHYSLRKLKKGTASVAVALSVIGAGLVVNTNEVSARVFPRGTVENPDKARELLNKYDVENSMLQANNDKLTTENNNLTDQNKNLTTENKNLTDQNKNLTTENKNLTDQNKNLTTENKELKAEENRLTTENKGLTKKLSEAEEEAANKERENKEAIGTLKKTLDETVKDKIAKEQESKETIGTLKKTLDETVKDKIAKEQESKETIGTLKKTLDETVKDKIAKEQESKETIGTLKKILDETVKDKIAREQKSKQDIGALKQELAKKDEGNKVSEASRKGLRRDLDASREAKKQVEKDLANLTAELDKVKEEKQISDASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDAKPGNKVVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN
What is the function of this protein?
Mediates the attachment of S. pyogenes to skin epithelial cells through the binding of the human membrane cofactor protein CD46.  Also binds to the factor H and factor H-like protein 1.  These interactions could contribute to the fact that the M6 protein protects the bacterium from the phagocytosis by regulating the complement activation on the bacterial surface.
What are the official names of this protein?
M protein, serotype 6.
What is the protein family that this protein belongs to?
Belongs to the M protein family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.