PharMolix/UniProtQA huggingface dataset:
Protein: ADDB_HELMI
Sequence: MSLRFILGRAGTGKSRACLDEIAQELKGSPQGPPLLFLVPEQATFQTERALATMPGLGGTIRAQVFSFRRLAYRVLQEVGGSARIPIGDLGKRMILRNLLEKHKDELRLFHRSAGQPGFADALAGALSELKLYNIDATSLDRCQTEVIERQGAGLLADKLHDLALLYGALKTFLEGKYTDPDDYLHLLAQRIPGSVMLRDAEVWVDGFAGFTPQELSVLAALMSACRRVNVALCLDPTELDEPCDLDDPFFRTRETQAKLLQLAFDRGIVIEKALHLVPAPGQSAPRFQHPELQHLESFYFRRPAPPWLGGTQSLFVCAAANRRSEVEGAAREIIRLCRDQGYRWRDVAVLLRDLESYYDSIESVFSDFGIPLFIDSKRPAPHHPLVELIRSALEAVLRDWAYEPVFRYLKTDLVPLSRGETDRLENYVLAHGIRGRRWRDREPWLFRRRLTLGEDALSEFSDQELAELAEINGARDRARAALASFHKAVVGAKAVRPITAALYQLLVDLKAPEQISCWIAEAEAAGRIEEAHAHRQVWAAVIDLFDQIVESLGETPLDLATYAVVMEAGLDSLKLSLIPPELDQVFVGSLDRSRCPGIRAAFVLGVSEGVLPARPKDDGIFDDKERERIYALTGLELAPGSRRRLFDEEYHIYVALTRASERCYLSYPLADAEGRAQLPSSVIARVRELFPQVTERTWLLEPGSLPTGAGLSGSAFAGAATAETAAMAQTALAARTTKEAAMSAVERELAEEYIVHPARSLSYLIPSLREALARRPVPLVWWAVYSWLAERPAWRELLARVLSGLWHKNREQDLPKPVSRRLFGDPLRASVSRIERFLACPFSHFISHGLRLKERRIFRLAAPDLGEFFHAALKQFGERLRRDRLDWGALPREELFRLTGEVVSDLAPQLQNEILLSTARHRYLTGRLQQTLSRAVIVLGEHARRGQFRPLALEVGFGPEELLPPVQVPLTGGRWMDLVGRIDRIDGFFVGDASWLRVIDYKSNRANLKLADIAHGLKLQLLAYLDVALRHGNRLLQGCALGEDRPSSLSAATACHPGGMLYFGICDPLLSTGGPLTRDEAERAILKEAKMCGHVLADPAVVAAMDGQTRQGYSPLIPVGLKKEGGFYSASSVLTMEQFALLRQYLQSIVARVGEAILDGLVSIRPHRRDDRLACSFCPYKSVCQFDLLLQDNDYRLLIDDPPEKIWEKIAAGPKAIFEGVIR
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: ARCH_DICDI
Sequence: MESYGLGQLKNFEYLDHTADIMFHTWGKDLKEALEQMVLIMNNYMVELDSVELDDSATEQTISVNGHDMDSLLFALLDEFLFVFSTEFIIFKQVQIISFDRENFSIKAIGKGVELDKSKHTTGTEIKAITYSCMKIEENPDKSDIHVIVDI
What is the function of this protein?
Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB.
What are the official names of this protein?
Protein archease-like.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: NIFW_FRAAL
Sequence: MSATTDAGQLAEFNRCSTAEQYFDLLEVDYDPRVVAVNRLHILKHFAGELAKLQDAGADTENPRHLLRDYRDALVRSYEAFTNAGALDHRLFKVLKDRAPQAADFVPTSEITVQRPGSTQPSETSERTEEAR
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: RL10_ACTSZ
Sequence: MALNLQDKQAIVAEVNEAAKGALSAVIADSRGVTVDKMTELRKAAREAGVSMRVVRNTLLRRAVEGTEFECLTDTFTGPTLIAFSNEHPGAAARLFKDFAKANDKFEIKGAAFEGKIQDIDFLATLPTYEEAIARLMGTMKEAAAGKLVRTFAALRDKLQEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SAK_BPP42
Sequence: MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASYFEPTGPYLMVNVTGVDGKRNELLSPRYVEFPIKPGTTLTKEKIEYYVEWALDATAYKEFRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVVIEKK
What is the function of this protein?
Potent plasminogen activator that converts plasminogen into plasmin.  It forms a 1:1 complex with plasmin, which in turn activates other plasminogen molecules.
What are the official names of this protein?
Staphylokinase, Sak42D.
What is the protein family that this protein belongs to?
Belongs to the staphylokinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: C163A_HUMAN
Sequence: MSKLRMVLLEDSGSADFRRHFVNLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAIWQCKHHEWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIFVALFFLTKKRRQRQRLAVSSRGENLVHQIQYREMNSCLNADDLDLMNSSENSHESADFSAAELISVSKFLPISGMEKEAILSHTEKENGNL
What is the function of this protein?
After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.
What are the official names of this protein?
Scavenger receptor cysteine-rich type 1 protein M130, Hemoglobin scavenger receptor.
What are the subcellular locations of this protein?
[Soluble CD163]: Secreted. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Note=Isoform 1 and isoform 2 show a lower surface expression when expressed in cells.
Protein: ARI4B_MOUSE
Sequence: MKALDEPPYLTVGTDVSAKYRGAFCEAKIKTAKRLVKVKVTFRHDSSTVEVQDDHIKGPLKVGAIVEVKNLDGAYQEAVINKLTDASWYTVVFDDGDEKTLRRSSLCLKGERHFAESETLDQLPLTNPEHFGTPVIGKKTNRGRRSNHIPEEESSSSSSDDDEEERKQTDELLGKVVCVDYVSLEKKKAMWFPALVVCPDCSDEIAVKKDNILVRSFKDGKFTSVPRKDVHEITSDTVPKPDAVLKQAFDQALEFHKSRAIPANWKTELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDRGTPINKRPVLGYRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYGFEEYCRSANIDFQMALPEKVLNKPCKDCENKEVKVKEESETEIKEVNVEDSKNVMPKEETPAEDESERKENIKPSLGSKKSLLECIPAQSDEEKEAHITKLEENENLEDKDGGRARTEEAFSTEVDGEEEQARSGDETNKEEDEDDEEIEEEEEEDEEEDEDEDDDDNNEEEEFECYPPGMKVQVRYGRGKNQKMYEASIKDSDVEGGEALYLVHYCGWNVRYDEWIKADKIVRPADKNVPKIKHRKKIKNKLDKEKDRDEKYSPKNCKLRRLSKSPFQSNPSPEMVSKLDLADAKNSDTAHIKSIEITSILNGLQASESSAEDSEQEDERCTQDVDNIGKDESKVEHSTHSRNELISKEEQSSPSLLEENKVHTDLVIAKTVSKSPERLRKDMEAISEDTDFEEEDEITKKRKDVKKDTTDKALKPQTKRGKRRYCSADECLQTGSPGKKEDRTKSKEPLCTENSSNSSSDEDEEEKSKAKMTPTKKYNGLEEKRKSLRTTSFYSGFSEVAEKRIKLLNNSDERLQNNRAKDRKDVWSSIQGQWPKKTLKELFSDSDTEAAASPPHPAPDEGAVEESLQTVAEEESCSPIMELEKPLPASVDNKPIEEKPLEVSDRKTEFPSSGSNSVLNTPPTTPESPSSVTITEASQQQSSVTVSVPLPPNQEEVRSIKSETDSTIEVDSVVGELQDLQSEGNSSPAGFDASVSSSSSNQPEPDNPEKACTGQKRVKDTQGVGSSSKKQKRSHKATVVNNKKKGKGTNSSDSEELSAGESVTKTQTIKSVPTGMKTHNSKSPARVQSPGKGGRNGDKDPDLKEPSNRLPKVYKWSFQTSDLENMTSAERISILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERESAATSSSSSSPSSSSITAAVMLTLAEPSMSSASQNGMSVECR
What is the function of this protein?
Acts as a transcriptional repressor.  May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity).  Plays a role in the regulation of epigenetic modifications at the PWS/AS imprinting center near the SNRPN promoter, where it might function as part of a complex with RB1 and ARID4A (PubMed:17043311).  Involved in spermatogenesis, together with ARID4A, where it functions as a transcriptional coactivator for AR (androgen receptor) and enhances expression of genes required for sperm maturation.  Regulates expression of the tight junction protein CLDN3 in the testis, which is important for integrity of the blood-testis barrier (PubMed:23487765).  Plays a role in myeloid homeostasis where it regulates the histone methylation state of bone marrow cells and expression of various genes involved in hematopoiesis.  May function as a leukemia suppressor (PubMed:18728284).
What are the official names of this protein?
AT-rich interactive domain-containing protein 4B, ARID domain-containing protein 4B, 180 kDa Sin3-associated polypeptide, Sin3-associated polypeptide p180, Histone deacetylase complex subunit SAP180.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHPS_SYNY3
Sequence: MDQLDQLSDYFPPPLPVGQTLFDWGKRTYVMGILNTTPDSFSDGGEFNSLPTAIHQAKTMVQGGAHIIDIGGQSTRPGAETVSLKEELERTIPIIQALRQELDIPISIDTTRAEVARQALQAGADMVNDISGATFEPEILAVAAQHKAPIILMHIRGNPQTMQNLTDYGDLIGEMRQFFSAQVDLARHYGVLPEQIILDPGIGFAKTAEQNITLLRQLPELKRLGFPLLVGPSRKSFIGKILDQPDPKERVWGTGATCCRAIAGGADIVRVHDVEAMAQICKVADALWR
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: AMT4_PELSC
Sequence: MSHILRAAVLAAVLLPFPALADQAGKSPAGVRYHGGDEIILQGFHWNVVREAPNDWYNILRQQASTIAADGFSAIWMPVPWRDFSSWTDGGKSGGGEGYFWHDFNKNGRYGSDAQLRQAAGALGGAGVKVLYDVVPNHMNRGYPDKEINLPAGQGFWRNDCADPGNYPNDCDDGDRFIGGESDLNTGHPQIYGMFRDELANLRSGYGAGGFRFDFVRGYAPERVDSWMSDSADSSFCVGELWKGPSEYPSWDWRNTASWQQIIKDWSDRAKCPVFDFALKERMQNGSVADWKHGLNGNPDPRWREVAVTFVDNHDTGYSPGQNGGQHHWALQDGLIRQAYAYILTSPGTPVVYWSHMYDWGYGDFIRQLIQVRRTAGVRADSAISFHSGYSGLVATVSGSQQTLVVALNSDLANPGQVASGSFSEAVNASNGQVRVWRSGSGDGGGNDGGEGGLVNVNFRCDNGVTQMGDSVYAVGNVSQLGNWSPASAVRLTDTSSYPTWKGSIALPDGQNVEWKCLIRNEADATLVRQWQSGGNNQVQAAAGASTSGSF
What are the official names of this protein?
Glucan 1,4-alpha-maltotetraohydrolase, G4-amylase, Exo-maltotetraohydrolase, Maltotetraose-forming amylase, Maltotetraose-forming exo-amylase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPT_CLOPE
Sequence: MLDFFSKKGNEDSEEIVLIEDKMPKHIAIIMDGNGRWAKKRGLPRTMGHRAGVKTIKTIVKECDKLGVKYLTLYAFSTENWKRPEDEVNALMKLVVEFIKNEIDELHQNGVRVQTIGDLSRFPEEPKKAILWAMEKTKDNTGVVLSLALNYGGRNEIVRGIKSVIEDVKAGKISIDDINEDMFNDYLYTKGMPDPDLIIRPSGEQRLSNFLLWQCAYSEFWYSQINWPDFNGEDLRKAIFDYQNRDRRFGGIK
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: YD1E_SCHPO
Sequence: MFIAKSIVIGLLICVLFFFFFVSRFNDKYELQPLLTLGLLNASLTALSDLLAQALDSYKLLKFRNKRDVSLEKYGNTILLPASTSKLDVHRTIRYAAYGLCLTPIQFRWFVALSNVIQTENPFIAIVLRVALDQFIFAPLGIVFFFLFMGITECKSYERLKSYFRKHYWPTLKANYILWPAVQLFNFTFVPLVLQVIFANAVSMVWTAYLSLKNSSPNADV
What are the official names of this protein?
Uncharacterized protein C4G9.14.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DXR_BEUC1
Sequence: MSARTVVLLGSTGSIGTQALDVVAAAPGRFQVVGLAAGGSDLELLARQAVAHDVPVVAVAAGEQDDVAAAIRAAGGRRTEVLTGPGAAADLAGRGADVVLNGITGSVGLAPTLAALEAGSTLALANKESLVAGAALVRAAQQRADQIVPVDSEHSAIAQALRSGARSEVARLVLTASGGPFRGWSREQMAGVTPEQALAHPTWAMGPVVTTNSATLMNKGLELIEAHVLFDVPVADITVVVHPQSVVHSMVEFVDGSTIAQASPPDMRLPIALGLAWPDRVPGAASPCRWDAATSWTFEPVDDAAFPALDLAREAVKASPLHPAVLNAANEEAVAAFLDGRLPFLDVVGTVARVLGEYPDPPDGALSLEGVQAAEAWARARSRALVADGPSRER
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: TAF1B_HUMAN
Sequence: MDLEEAEEFKERCTQCAAVSWGLTDEGKYYCTSCHNVTERYQEVTNTDLIPNTQIKALNRGLKKKNNTEKGWDWYVCEGFQYILYQQAEALKNLGVGPELKNDVLHNFWKRYLQKSKQAYCKNPVYTTGRKPTVLEDNLSHSDWASEPELLSDVSCPPFLESGAESQSDIHTRKPFPVSKASQSETSVCSGSLDGVEYSQRKEKGIVKMTMPQTLAFCYLSLLWQREAITLSDLLRFVEEDHIPYINAFQHFPEQMKLYGRDRGIFGIESWPDYEDIYKKTVEVGTFLDLPRFPDITEDCYLHPNILCMKYLMEVNLPDEMHSLTCHVVKMTGMGEVDFLTFDPIAKMAKTVKYDVQAVAIIVVVLKLLFLLDDSFEWSLSNLAEKHNEKNKKDKPWFDFRKWYQIMKKAFDEKKQKWEEARAKYLWKSEKPLYYSFVDKPVAYKKREMVVNLQKQFSTLVESTATAGKKSPSSFQFNWTEEDTDRTCFHGHSLQGVLKEKGQSLLTKNSLYWLSTQKFCRCYCTHVTTYEESNYSLSYQFILNLFSFLLRIKTSLLHEEVSLVEKKLFEKKYSVKRKKSRSKKVRRH
What is the function of this protein?
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription.  Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
What are the official names of this protein?
TATA box-binding protein-associated factor RNA polymerase I subunit B, RNA polymerase I-specific TBP-associated factor 63 kDa, TAFI63, TATA box-binding protein-associated factor 1B, TBP-associated factor 1B, Transcription initiation factor SL1/TIF-IB subunit B.
What is the protein family that this protein belongs to?
Belongs to the RRN7/TAF1B family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYWM_CAEEL
Sequence: MIFSGKFTSHLLNYGFKPNNLRLLSTSTHPTIYFTGIQPTGIPHLGNFFGSIEPWTELQNSVDKNILMMLSVVDQHAISLGPLPANELRQNTHQMTASLIACGVDPNRTLLFRQSDVPQIAQISWILGSLQTTSKLARLPQYKEKKERFKKGDIPVGLLTYPLLQAADVLTFKATTVPVGEDQSQHLNLLGGLAYAFNKTYETEIFPIPKQLTRESHARIRSLREPEKKMSKSSGGPRSRIEITDSRSTIIEKCQKAQSDNAGKVTYDKENRLAVSNLLDLYSAVTKTQTSEIDFSNWTTLDLKMNLAEAVDKRLAPIRQKFEELQNTGEVDKVLTENGEKAREIAEKNLEEIRRTIGFL
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, mitochondrial, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: QUEF_RHOBA
Sequence: MSDTASFRDTLEVFENPAPTRNFTIEHHCPEFTSVCPKTGQPDYGTIVFTYVPDRVCVELKSLKMYLQKFRNEGIFYEQVTNRILDDFVAVVQPRKVTVESKWTPRGGLNSNIIVTYPDEA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_HISS2
Sequence: MKYSAKNTALSQIDSNIILAVFEDGELSPTAMQFDQLSQGYLTRLIQVGEVSGKQGQVLILRDIPNCQAQRIFIVGCGKKDKITERQYKQIIQKTIQTILETQASEVVSFLNEIELKNRDIHWNIRFAIETIEASHYQFDTFKSKKTDASLVLDRFIFNVPTELQQNALQAISYAQAIALGVKYAKDIANCPPNVCNPTYLAEQAQSLAKHSNLINVQVLGEKEMAELNMFSYLAVSQGSANEAKMSVIEYRNHPDKNAKPIVLVGKGLTFDAGGISLKPADSMDEMKYDMCGAASVFGVMYALATLQLPLNVIGVLAGCENLPDGNSYRPGDILTTMSGLTVEVLNTDAEGRLVLCDALTYVERFNPELVIDVATLTGACVVALGQHNSGLIATDGKLAEKLLNAAEETTDKAWRLPLSEEYQEQLKSNFADLANIGGRWGGAITAGAFLANFTKNYPWAHLDIAGTAWLQGTNKGATGRPVSLLTQFLINQSK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_PARDP
Sequence: MAIERTLSIIKPDATKRNLTGKINAKFEEAGLRIVAQKRIQLTLAQAGQFYAEHKERPFYGELTEFMTSEPVVVQVLEGEGAILKNREVMGATNPANADEGTIRKEFALSVGENSVHGSDSPEAAAREIAFFFSGLELVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLHA2_CYPCA
Sequence: MFWTRYAGASVLLFLMLIHLGQLYPRNYMNNFGCEECKLKENNIFSKPGAPVYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKEFKQVLVNDIKLVNHTDCHCSTCYYHKS
What is the function of this protein?
Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Glycoprotein hormones alpha chain 2, GTH-alpha, Gonadotropin alpha chain 2.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL11_BORPD
Sequence: MAKKIVGFIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAKTQGMEPGLPIPVVITAFADKSFTFIMKTPPATVLIKKAAGVQKGSAKPHTDKVGTLTRAQAEEIAKTKEPDLTAADLEAAVRTIAGSARSMGITVEGI
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: REV_CAEVC
Sequence: MDAGARYMRLTGKENWVEVTMDGEKERKREGFTAGQQDIQNSKYPDIPTGHSHHGNKSRRRRRKSGFWRWLRGIRQQRNKRKSDSTESLEPCLGALAELTLEGAMEKGPAEAARPSADDGNLDKWMAWRTPQK
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rev, Rev-C.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: SMAKA_MOUSE
Sequence: MGCMKSKETFPFPTTLDIDKLHESEEAFIPDDSSQYRTPSPGEQQQVQEVKKLPEPGAVIGALILEFADRLASEIVEDALQQWACENIQYYNIPYIESEGSDTTIN
What is the function of this protein?
Binds to type I regulatory subunits of protein kinase A (PKA-RI) and may anchor/target them to the plasma membrane.
What are the official names of this protein?
Small membrane A-kinase anchor protein, Small membrane AKAP, smAKAP.
What is the protein family that this protein belongs to?
Belongs to the small membrane AKAP family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: VP4_MPRVN
Sequence: MNRSQVEYQSEIVPDPLEQQIPEQLFEGLQVAENAVALTADTFSPDVFGALVSRFLTVFTDESNTPQGYYPIWDGYETNNLGNPGVFSGFINSILVAGTGNPNFHSDITDLLGDTGPGISSEHGYLLPGYGTRITRRQPIPLDMLEHARGTLVEARTSYGQDGRGPTYQSGNQSYVSALRSMFTGDVASSLIADERGGGHISGALANGLFNVAPVVYKTSEIGDTDTFKRRVSNAPSIGDIKLVINGQSGPDLKSEKDRIYQIPDDDRYVTKITSHCDLDDRKLIVEKVKLNVPRRIKISAHAKADYNTIVADSLRTALVAAFNGKVYDCLQLRSSEDHGPGVVIENMPLHEYPHKSMTLSGETTITAKARDEFVNVKFDTKSTSGTISIPITKMKFVFAGIMKYDPKSATYTYSATNVVTNIFDGDVGVARLRRSPIRVNKRSYDYNDDRNFRPESLKAEISMPYDRRNSGAVIHGLHNVLERYDLERKLETHDPWTGLPFSNSIMSPPGEDDNLLRYSGIEYDDIHAIYTSPSTFNGTILGLTSPSGKEIVERVADMCLHMLLSQHEVDLYGRDIIASTKLSDPKLSQAIKLIKARLQREIYDKSAITSMHDKLWFTNVNESVAPDDRIVVDIMLARYLLSLTHHIVYPISEDTYRSTLLLPPRINKAKYIPVSLSEEGYRVVTPTLSVVYSYFMKEPGSRQLLKQYISKDGNFKQDPQNKLDWLSAINRYEPRNFKELVNNSTQGRIELHAIVRAPLVEVTYESVLDGTYTHCIICDNCKIITLDYLIQSTVYQLCTKSESMDGVQSVLSKVHNNGGKLFVIYDKWFILLFVIPEKTDVPPIVFVQTSTRAARIVPHTKNTNSSLRRADAKYDYEVLMQSAVSCDLLYMSKTIEWSSGRRVGQLLRDRSVKYA
What are the official names of this protein?
Uncharacterized protein VP4.
Protein: RL25_RHOPT
Sequence: MTSVLELKATARPKSGKGAARAERRAGRVPGVIYGDNQSPLPISVEEKELRLRILAGRFLTTVFDVVLDGKKHRVIPRDYHLDPVRDFPIHVDFLRLGAGATIRVSVPLHLKGLEVAPGVKRGGTFNIVTHTVELEAPAENIPQFIEADVSTLDIGVSLHLSDIALPTGVKSVSRDDVTLVTIVPPSGYNEDKAAAGAAPAAAAAPAAAAKAPAAAAKAPAAAAPAAKKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ASNA2_CHLRE
Sequence: MAADMPDPTLQNVVDQKELKWIFVGGKGGVGKTTTSSSLAVALAESGTRNRVLIISTDPAHNLSDAFRQKFTKTPTLVNGFTNLFAMEVDPQPDIGEMEQLEWAQDSFLTELAGSIPGIDEAMSFAEVMKQVQTMDYDTIVFDTAPTGHTLRLLNFPTILEKGLSKLVALKGAMGGMMGQVTRMLGGMAGGGEGAADLPDQLLGKVEGMLDVVRKVSAQFKDPLLTTFVAVCIPEFLSLYETERLVQELAKFEIDCRNIVINQIIFPESVGGSRLLDARVRMQQKYLDQFYELYEDFHILQLPLLEEEVRGPEALKAFAVNLLKPYVPAPPTDAAARQAALVSEVAALKKRVAELEAALAKK
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis (PubMed:28382961).  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity).
What are the official names of this protein?
ATPase ARSA2, Cr-ArsA2, Arsenical pump-driving ATPase 2, Arsenite-stimulated ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum.
Protein: GLB3_LUMTE
Sequence: MLRQLLVLVGLAVVCLADEHEHCCSEEDHRIVQKQWDILWRDTESSKIKIGFGRLLLTKLAKDIPDVNDLFKRVDIEHAEGPKFSAHALRILNGLDLAINLLDDPPALDAALDHLAHQHEVREGVQKAHFKKFGEILATGLPQVLDDYDALAWKSCLKGILTKISSRLNA
What are the official names of this protein?
Extracellular globin-3, Erythrocruorin, Extracellular globin III, Globin C.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TOLB_ALBFT
Sequence: MQMMKKRILLCLLVGMTCLPVLAQFRVEVSGVGLTQLPIAVSAFRGQDSVPQKIAAIVQADLERSGQFRGVDTVGAALDEGTRPDVALWRQKGADSLVTGSVSRLADGRYDVRFRLWDVVRGQDLGGQSYAVTQADLRLSAHRIADFIYEKLTGDKGAFSTRITYVTKAAQRYQLWVADADGENAQSALASPEPIISPAWSPNGSQIAYVSFESRKPVVYTHDVATGKRRLIANFRGSNSAPAWSPDGRTLAVTLSRDGGSQLYAIDAGGGEPRRLAQNSSIDTEPVYAPDGKNIYFVSDRGGAPQIYRMPVTGGGAERVTFTGTYNISPAISPDGRWLAYISRVSGAFKLHVLELASGAVTAITDTTADESPSFAPNSRLIVYATQSQGREALMTATVDGKVKARLAGQNGDIREPGWGPFQKQ
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.