PharMolix/UniProtQA huggingface dataset:
Protein: SYV_CLOPE
Sequence: MDNKNISTTYNPKEFEERLYSNWQEKKYFTPVIDKSKKPYTIIMPPPNITGKLHLGHALDNTLQDMLIRFKRMQGYCTLWLPGQDHASIATEVKVENELLKEGLYKKEMGREAFLEKVWEWTDEYRERIREQLKKMGCSADFTREAFTMDENLSKAVRHVFVKLYKEGLIYQGNRITNWCPKCQTALSDAEIEYEEKEGNFWHIKYPVVGSEEFLEIATTRPETLLGDSAVAVNPSDERYAHLVGKMLKLPLTDREIPVIADDYVDVEFGTGAVKITPAHDPNDFEVGKRHNLPQIRVMDDSGVINHLGGKYKGLDRYEARKQMVADLEELGLLVKIKPHTHNVGTHDRCGTVVEPIISKQWYVKMQSLADPAIEVVRNKGTKFVPERFEKTYFNWMENIQDWCISRQLWWGHRIPVFYCKDCGEIMVELEDPTKCCKCGSENIEQDKDVLDTWFSSALWPFSTLGWPDRTDDLEFFYPTSTLVTGYDIIFFWVARMIFSGIHNMGETPFDTVLIHGIIRDAQGRKMSKSLGNGVDPLEVIDEYGADALRFMLVTGNAPGNDIRYIPERVEAARNFANKIWNASRFVMMNLDRELMDKYKDCQEYSLADQWILSRTNSLIKEVTENMEKYELGIALQKVHDFLWTEFCDYYIELVKPVLYGDDEKAKGVVFNVLYTVLNTGLKLLHPVMPFITEEIYTHLSTETESITIATWPTYDEALNNEKAEKDMTFIMEAIRSLRNLRAEMNVPPSRKAKVMAYASEEAKDAFINGGAYLEKLASASEVTFLDNKDNLDNNLVSVVVKGGELFLPLLDLVDREKELERLNKEKTKLEGEILRVEKKLSNERFVSKAPEAVVNEERAKGVKYKEMLEAVLERIEALQ
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSD4_BOVIN
Sequence: MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDWRALMKRKKMKANIKLVGSGFPLPTSDLDDSLTEEIDEKIGFRSDTNFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLESELGQGEKSIHQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKERLRIQKEGHLQ
What are the official names of this protein?
Myb/SANT-like DNA-binding domain-containing protein 4.
Protein: KTHY_STRA3
Sequence: MKKGLMISFEGPDGAGKTTVLEAVLPLLREKLSQDILTTREPGGVTISEEIRHIILDVKHTQMDKKTELLLYMAARRQHLVEKVLPALEEGKIVLMDRFIDSSVAYQGSGRGLDKSHIKWLNDYATDSHKPDLTLYFDVPSEVGLERIQKSVQREVNRLDLEQLDMHQRVRQGYLELADSEPNRIVTIDASQQLDEVIAETFSIILDRINQ
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: CREG1_MOUSE
Sequence: MAARAPELARSLLAALLAPALVALLVSPASGRGGRDHGDWDVDRRLPPLPPREDGPRVARFVTHVSDWGSLATISTIKEVRGWPFADIISISDGPPGEGTGEPYMYLSPLQQAVSDLQENPEATLTMSLAQTVYCRNHGFDPQSPLCVHIMMSGTVTKVNKTEEDYARDSLFVRHPEMKHWPSSHNWFFAKLKISRIWVLDYFGGPKVVTPEEYFNVTLQ
What is the function of this protein?
May contribute to the transcriptional control of cell growth and differentiation.  Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein.  The transcriptional control activity of cell growth requires interaction with IGF2R (By similarity).
What are the official names of this protein?
Protein CREG1, Cellular repressor of E1A-stimulated genes 1.
What is the protein family that this protein belongs to?
Belongs to the CREG family.
What are the subcellular locations of this protein?
Secreted.
Protein: RAD18_YEAST
Sequence: MDHQITTASDFTTTSIPSLYQLDTLLRCHICKDFLKVPVLTPCGHTFCSLCIRTHLNNQPNCPLCLFEFRESLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPTPVPENEEVPGPENSSWIELISESESDSVNAADDDLQIVATSERKLAKRSMTDILPLSSKPSKRNFAMFRSERIKKKSKPNEQMAQCPICQQFYPLKALEKTHLDECLTLQSLGKKPKISTTFPTESNPHNKSSSRFKVRTPEVDKSSCGETSHVDKYLNSMMSAEHQRLPKINFTSMTQSQIKQKLSSLGLSTNGTRQNMIKRYNHYEMLWNSNFCDSLEPVDEAELKRQLLSWDVSHNKTPQNSSNKGGISKLMIMKSNGKSSSYRKLLENFKNDKFNRKGWMVMFRKDFARLIREAKMKIKTGSSDSSGSVGHSNDGDGVEKVQSDQGTEDQQMEKDQDTVINEDRVAGERNLPNEDSTDADLSRELMDLNEYSKDPPGNN
What is the function of this protein?
E3 RING-finger protein, member of the UBC2/RAD6 epistasis group.  Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.  The UBC2-RAD18 complex cooperates with RAD5 and the UBC13-MMS2 dimer to attach mono-ubiquitin chains on 'Lys-164' of POL30, which is necessary for PRR.  The UBC2-RAD18 complex is also involved in prevention of spontaneous mutations caused by 7,8-dihydro-8-oxoguanine.
What are the official names of this protein?
Postreplication repair E3 ubiquitin-protein ligase RAD18, RING-type E3 ubiquitin transferase RAD18, Radiation sensitivity protein 18.
What is the protein family that this protein belongs to?
Belongs to the RAD18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YPJF_ECOLI
Sequence: MNTLPATISQAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDAGITLADAVNFLVEKYELVRIDHRGFSWQQQSPYISVVDILRARRSTGLLKTNVK
What is the function of this protein?
Toxic component of a type IV toxin-antitoxin (TA) system (PubMed:14594833, PubMed:28257056, PubMed:28931012).  Acts as a dual toxin inhibitor that blocks cell division and cell elongation in genetically separable interactions with FtsZ and MreB (PubMed:28931012).  Overexpression results in inhibition of growth in liquid cultures (PubMed:14594833, PubMed:28257056, PubMed:28931012).  Overexpression leads to formation of lemon-shaped cells; inactivated by overexpression of cognate antitoxin YfjZ but not when the 2 genes are coexpressed from the same plasmid (PubMed:28257056).  Also neutralized by overexpression of non-cognate antitoxins YafW and CbeA (PubMed:28257056).
What are the official names of this protein?
Toxin YpjF.
What is the protein family that this protein belongs to?
Belongs to the CbtA/YkfI/YpjF toxin family.
Protein: PSIT2_PSICU
Sequence: MSLERSTSPNPTERTSLLSDTASTISSRDDVEQSSLKQRRTPIPTGQLGGKVSMHSIIINAEGHLWPYINQFVNDIGVSDGNPRNVGFYSGLIESVFACGEVCSIFMLSRLSDRIGRRPVLLPSALGIAVFTALFGLSSSFTMMLTLRVCAGLLAGATPIVHSIVSELTDDTNNALVVPLYGLITPIGFAIGPLIGGTLEHAATKYPNVFGYELFRKYPYFLPSFVPCCMAIVGVTFGYFFLKETLPSLVKSKKRLERQRSSSSISSENSTLYGATEHIRDSTEETAADEEPDSKPKGITELIRDPSIRAIMASGTFLMFLYTSSDVIFSLYCFTAVEDGGVGLPPEKIGYAFSVAGLIAMLMQLCITPWVLRTFDKAKVYHFCMCSFPLVFALMGCLNPLAQTGYSEINKTLHPTTTGLLYAAIAILLLLARVCVMAFPISMMLVKQTADKHSLATANGLVQVAMTLARAFCPTISSSVFAYSTSHNILGGHFWVVVMVFISLVGVWQSTKIARVTKTKEQL
What is the function of this protein?
Major facilitator-type transporter; part of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product (PubMed:28763571).
What are the official names of this protein?
Major facilitator-type transporter psiT2, Psilocybin biosynthesis cluster transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MDTD_SHIF8
Sequence: MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTAIPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSKGTGLSPLAIAGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMAFIIALPAFIFARVPNDTHQNVAISRRKRSAQ
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ST32C_HUMAN
Sequence: MRSGAERRGSSAAASPGSPPPGRARPAGSDAPSALPPPAAGQPRARDSGDVRSQPRPLFQWSKWKKRMGSSMSAATARRPVFDDKEDVNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLVQLFSTVSVQYVPTWSKEMVALLRKLLTVNPEHRLSSLQDVQAAPALAGVLWDHLSEKRVEPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNKSRDNSRDSSQSENDYLQDCLDAIQQDFVIFNREKLKRSQDLPREPLPAPESRDAAEPVEDEAERSALPMCGPICPSAGSG
What are the official names of this protein?
Serine/threonine-protein kinase 32C, PKE, Yet another novel kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: OPDG_PENO1
Sequence: MDHLRDSLLSSLPRDSPSIGAMDYARRDRESTRQSVARGDFEELRQAAFYNRTWVVTSRFCDIGAGVDSVEVHVHSLWYIYYELSRHISSQSPEHEGLVLDILRIQGMGPLNRPARGNSGVDIARTVDGTLWTDLPFLVGDMTSFWIEHGATMSGTHRLNLATFLAKLASARVAKDRMCQIALLLFRNVFETSLELRTGDESDGEDLNRGMRQLEVFHLLPAAVAWLKIAAHNLALLSEVCWSDCPSHISQGGEDFLESELGRRSPAGFSPWRYMFWMKRLHEIQGQAKEAGEKTLEELAADGIEYMSNTIQSRNSEIIRAFKSADSALHQDPHLSCLRNLAGFDDDEPEESQEIARES
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of oxopyrrolidines, polyketide-amino acid hybrid compounds with feature structures of tetramic acid (PubMed:36005526).  Does not seem to play a role in oxopyrrolidines A and B biosynthesis (PubMed:36005526).
What are the official names of this protein?
Oxopyrrolidines biosynthesis cluster protein G.
Protein: HLDD_SHIBS
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLDIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: DNAA_PARXL
Sequence: MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGRIADMARDFWHTPIDVQFVLDPKAGMRAPAAAAPAPASARPASAPGSMGGSAGNGAAVDAAVGAVQAAQTARANGANSANNAMANLNANARAAAEQNANARAAAEDSADLDLPSLDANEAAAARRTWRPGQSAGSNGNGETDSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLYGGVGLGKTHLIHAIGNQLLMDKAGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEFVSLNEDVAFFVAKHLRSNVRELEGALRKILAYSKFHGREITIEVTKEALKDLLTVQNRQISVENIQKTTADFYSIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_NEIMB
Sequence: MAKHEIEERGDGLIEKMVAVNRVTKVVKGGRIMAFSALTVVGDGDGRIGMGKGKSKEVPVAVQKAMDQARRSMIKVPLKNGTIHHEVIGRHGATKVFMQPAKEGSGVKAGGPMRLVFDAMGIHNISAKVHGSTNPYNIVRATLDGLSKLHTPADIAAKRGLTVEDILGVNHG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SYL_PSEPW
Sequence: MHEQYTPRDIEAAAQHFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGKLHMGHVRNYTIGDVIARYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAREVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDPADQTVLANEQVIDGRGWRSGALIEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDQASIGHEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMATQEKKGMPTSLLVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNLPVKAVVRTSAGDEVGSEWQAAYGEHGQLINSGEFDGLDFAGAFDAIEAALIRKELGKSRTQFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLPENVVPDGAGSPLARMPEFYECSCPKCGAAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGLVTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNPADVEIERDAKAKIIGARLKTDGLPVEIGGTEKMSKSKNNGVDPQSMIEAYGADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQGHVNQGLPGKLDLAALNDEQKVIRRAIHTAIKQASTDVGQYHKFNTAIAQVMTVMNVLEKAPQSTEQDRALLQEGLEAVTLLLAPITPHISHELWKALGHEQAVIDACWPVVDESALVQDTVTLVVQVNGKLRGQVEMPAAASREEIEAAARNNENVLRFIDGLTIRKVIVVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_SALPA
Sequence: MNQTLLSSFGTPFERVELALDALREGRGVMVLDDEDRENEGDMIFPAEIMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRVTTVRAAIKDGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIAFAGQHNMAVVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: ASSY_DEHMB
Sequence: MSEKVVLAYSGGLDTSAAVKWLQEKYGMDVIAVTIDVGNEKDFTLIKEKALKVGAKKAYVRDVRKEFAEDYIWKAIKANSMYEGVYPLATALARPLIAKVMVDIALEEGATAIAHGCTGKGNDQVRFDVGINTLAPHLKIIAPARQWGMTREQTMEYAQKWGIPVPISVKNPFSIDENLWGRSIECGLLEDPWNEPIPEVFAWTRPVEETPDEPEYLEVEFEQGVPVAVNGEKLSPLALIQKVHDIASLHGVGRIDHVENRLVGIKSREIYEAPAAVVLIAAHQALEAMTLSKSQLRFKQMVEATYSDIIYNGLWFSALRQDLDAFIDSSQRFVSGTVRLKLSKGSFRVVGRKSPYSLYHKGMATYDKGDQFDPSSAVGFITLWGLQAKLQAQLQPILEEEKGNKS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_STRAW
Sequence: MSDDSRPSPSGARTAAVIPAAGRGVRLGPGAPKALRALNGTPMLIHAVRAMAASRAVSLVVVVAPPDGTAEVKSLLDAHALPERTDFVVVPGGESRQESVKLGLDALPPGIDIVLVHDAARPLVPVDTVDAVIEAVRDGAPAVVPALPLADTVKQVEPAAVPGEPEPVVATPERARLRAVQTPQGFDRDTLVRAHETVTDNVTDDASMVEQLGARVVVVPGHEEAFKVTRPLDLVLAEAVLARRRLNDGF
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: CCME_DEIDV
Sequence: MTRPDSGSSPAPLSEARRRKRNPLPTVLGITALLGLAGFIAFGNLNKSLEYFVTPTEYQQQAAQLKGRPVRIGGLVKAVKYNPQSLELSFTVTDGGASFPVRYRGAVSDLFKENQGVVVRGEFEGQTFQARELIVKHSEQYDVPKTQAELRDLLEQSE
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: AMPA_BACC7
Sequence: MFYVQKELASHEAVIVALFEEEQTSSFVQELDKAFEGQLQVLLEEKELSTKKKAISKVHSLGKTEVKRYYFVGLGKKESYTTETLRSALGKTFKTLQAAKVQDAAILLDSFVTKKLDAIDVAHIAAEVQGLGTYELQTYKSDKKDRVELEKFTAITAEDAQEIEAALTVGYVHGRATNSARTLVNMPPNVLTATKLAEYAVELAEKYDMDYKVLEKEEMEELGMGALLAVNQGSVEPPKMIALIYKGKEEWTDVIGFVGKGITYDTGGYSLKPREGMVGMKGDMGGAAAVLGAMEIIGELRPEQNVIAVIPSTDNVVSGTAFKPDDVITSMSGKTIEVLNTDAEGRLALADGITYAKKLGANYLIDVATLTGGVIVALGNHTTGAMTNNEELFEQVLEASMETDESIWQLPIFDRDKERVRNSKFADLNNSPGREGHAVMAGTFLSEFAEDTPWVHLDIAGTSESSGAHDLGPAGATGAMVRTLATLVERFGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDN1_CANLF
Sequence: MDYFPMIFSLLFVAFQGAPEAAVLGAELSTGPDSRGEKPAPSAPWRPRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHIVPYGLGSPSRSKRSLKDLFITKATDHRKRCQCASQKDKKCWTFCQAGKELREQDSMEKGWNGHKKGKDCSELGEKSKQQQLVAGRKIRRLDAISNSIKTAFRVAKLKAELYRENKVTHNRTH
What is the function of this protein?
Endothelins are endothelium-derived vasoconstrictor peptides (By similarity).  Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity).  Also binds the DEAR/FBXW7-AS1 receptor (By similarity).
What are the official names of this protein?
Endothelin-1, ET-1, Preproendothelin-1, PPET1.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PB2S1_I33A0
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRITEMIPERNEQGQTLWSKMNDAGSDRVMVSPLAVTWWNRNGPVTSTVHYPKIYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTTTKEKKEELQGCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEARNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVNILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKALFQNWGIESIDNVMGMIGILPDMTPSTEMSMRGVRISKMGVDEYSSAEKIVPLHQSKVECSSPH
What is the function of this protein?
May participate in the inhibition of type I interferon induction through inhibition of the host mitochondrial antiviral signaling protein MAVS.  The knockout of PB2-S1 has no detectable effects on laboratory infected mice.
What are the official names of this protein?
PB2-S1.
What are the subcellular locations of this protein?
Host mitochondrion. Host cytoplasm, host cytosol.
Protein: DUSB_PSESM
Sequence: MSAVRIGPYTVHNGLILAPMAGVTDQPFRQLCRQLGAGLVVSEMVTSDMSLWNSRKSRLRMIHAGDPEPRSVQIAGGDAQMMADAARANVELGAQIIDINMGCPAKKVCNKAAGSALLKDEQLVNDILQAVVAAVDVPVTLKIRTGWDRDNRNGLTVAKIAEQAGIQALAVHGRTRADLYTGEAEYDTIAMIKQAVSIPVFANGDIDSPEKARHVLQATGADGLLIGRAAQGRPWIFREIEHYLLTGKTLPALQSSEVERILLEHLAALHVFYGDVMGVRIARKHVGWYLATLPGAREFRALFNRLEDTEAQCANVREFFSQGCKGPDNQNDKEVAA
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
tRNA-dihydrouridine synthase B.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusB subfamily.
Protein: SFXN2_DROME
Sequence: MSQVSTLIDVDKPLFDLSTFAGRFQYFAWMTDPRTVVVSSDRLLEAKAMVERYRKGDQSPPLKPEEVHYNMKLYNSAFHPDTGELQNFCGRMSFQVPGGMLITGGMLAFYRTVPAVVLWQFINQSFNAVVNYTNRNANSPTSVTQLGVAYVSATTSALVAAIGCKNYWSKKATPLFQRFVPFAAVAAANFVNIPLMRQNEIINGIEVKNDDGVVVGQSRLAAIKGIGEVVVSRIAMAAPGMLVLPLIMERLEKLPAYRRIKWINAPFQTLLVGCFLCFMVPTACALFPQQCSLDTSIMRTFEPELYEDLEKKTQGKVPKRVYFNKGL
What is the function of this protein?
Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria.
What are the official names of this protein?
Sideroflexin-2.
What is the protein family that this protein belongs to?
Belongs to the sideroflexin family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: OSTCN_FELCA
Sequence: YLAPGLGAPAPYPDPLEPKREICELNPDCDELADHIGFQDAYRRFYGTV
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: FKB1B_NEUCR
Sequence: MGVNKITHVAGTGPQPEAGQTVVIEYTGWLKDSSQADGKGAEFDSSIGRGDFVTQIGVGRLIRGWDEAVLKMKVGEKATLDISSDYGYGERGFHGHIPPNADLIFDVYLKGLQ
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 1B, FKBP-1B, FK506-resistance protein 3, Peptidyl-prolyl cis-trans isomerase fkr-3, PPIase fkr-3, Rapamycin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_SALA4
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTYKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MT1H_BOVIN
Sequence: MDPNCSCATGDSCACASTCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.  This isoform may play a role in regulating the transport, accumulation, and compartmentation of zinc in the hippocampus.
What are the official names of this protein?
Metallothionein-I, hippocampal, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: RLMD_SHEPC
Sequence: MAQFFKAKPNSSKQLSAKLSLNVDQLDHLGAGIAQYQGKVVFIPGALPDETVTVQLTEQKKNYARAKLIKVDAQSPERVEPECPHYHTCGGCDLQHMSLSGQREHKEAALLDIMAKFAGTEGGALSPALTGEGWHYRRRARLATLFDKNTKHLSLGFRAASSSNVVPISQCQVLAKPLSDLIVPFAKLLNQLSAKASLGHLELIAADNGHFAVLRITKALNDKDLAKLSAFAEQHQIYICLQDNEGQFQGVGVELVLPVYQLLDENAQSDAVSLSFTPGNFVQVNSQINKAMVAQAMDWLAPAPDERILDLFCGMGNFSLPLAKMGADVIGVEGVAEMVSQARVNAKANNLDKLTFYHGDLSADLSLEPWMGKIDKLLLDPARAGAFESLQWLKKMKPRKVLYVSCNPASLARDSTVLLERGYRLQRLGLIDMFPQTHHIEAMALFELTK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: MOBC_ECOLX
Sequence: MVKGSNKAADRLAKLEEQRARINAEIQRVRAREQQQERKNETRRKVLVGAMILAKVNSSEWPEDRLMAAMDAYLERDHDRALFGLPPRQKDEPG
What is the function of this protein?
This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids.
What are the official names of this protein?
Mobilization protein C.
Protein: ALDC_METMA
Sequence: MNIKYFLIFLILLAVTSFTLFSGCTGFAGNTPETSGKNSNVESIENLVPDISNNASDVLYQVSTIDALLLGVYDGVLPVSDLKTHGDFGIGTFDGLEGEMLALDGNYYQIKTDGIAYPVSGEITTPFATVTYFEADETFRLEKSANLSELEDFLDLNLPSENLFYAVKVDGNFSYVKARSVPRQEKPYLQLADAVSSQSVFEFENVSGTLVGFRTPEYVKGVNVPGYHLHFITENRSAGGHVLDLEMEKGDAALDITSIFLMELPASGDFYNAELGQNLQEDLEKVEK
What is the function of this protein?
Converts acetolactate into acetoin.
What are the official names of this protein?
Alpha-acetolactate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the alpha-acetolactate decarboxylase family.