PharMolix/UniProtQA huggingface dataset:
Protein: HSL1_CANAL
Sequence: MSTVVNRRSSHQFDSPSNHLDHSSSMNVDKVVQSVTNATKRLSQISTNTNNSNKKRKTQNKIGPWKLGRTLGRGSTGRVRLAKNTTTGQLAAVKIVPKSNFKKLENPKYKRSKEDATRLPYGIEREIIIMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKRGKLQEYEAINYFKQIINGINYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEVKEKLLETSCGSPHYASPEIVAGKNYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKVQSGKFNMPPELSFEAKDLITKMLKVNPRERITIDAILTHPLLAKYPEPTVSYSSTTTLDINSINIKQIESVDKIDKEILKNLSVLFHNCDEKTIISRLLSPNRCPEKMFYYLLMKYRNEHLSNSNSFNSSNDVDSARSLPRSTSYVKTTVTDHATGEKHTTVKKIQQSSSIYSNRSLLKKSTSAKGNVLSNITNRPNTPKQFSASSSFNKKKALHSKTQIYASRSRNASSRSLKSNSSTGRNGNNASVTSVNKIPEITGATVLQPIPSMAMNRGDEQQNKTKKNLTGTFGNKSLLNFQLICEEVFENDKENSKPVSKTPVSQLPPPPPPPIETPTSRTNSVKRGKTWSLARRERELAEQVRQRNEARENKLKAEELARKELEQEKKRIAEEKKRLEQQERELDEKQKLQEKQKAALEKLQKHQSAHDFEGLFASNRRSVTDMAPSSGMSSLDPRAHMVSRANTIGSPNLSSSSVNIDENASKVLHKFGIDVAPSPKRFSRASKTSTSKNLSSFLAPTVSRNLSSQLKTSSSKNLAGYLHGTTDTNGSAIAAKKKDNSTNKALTIEEFNAKERTSMSPSISKASVNKRNSNQSSYYRSMFSDNGNDDNVTKVRTRESHLSVQEEEEMDMENAIDEDISLIPNPRFSRFSFGGLLGSNTVANEEGDWTIMNSTLNHSNTVVRRTHNKSSTMLGLGIKMRDTTTIKEDEEFEDEKPFISVPSSEDDEGNTHKNKRGGLRDSGNYDFDEEHSVASTANTEYSDVASQGQQRPGSHTIHQLETELSNFDLLSYRVADIGKVNKHKPSIVDSKETLLKNHSSDEATIEVKEDNNEHDFNDKIKQHYDDNGDSEEDDEDEDEEEEDDDDDDDARSSFEARPHSHNYSLAEITSESPVGGGYESPSIANDFKKSRHSTGIFSTTQFPRSPYVVNNNGDSNKDENSQQQTKHMLNDGHKGLITSPVQDTFGSKKPVESNSLFRRLSLNPNRAAPKAPAPPPPSAPTSSAAKANISQPLSSPTKGHNRFSRISIGSKNMLQKEDKSTKSNWFKKFFHSLTTPSTKEQSGNSSSKVASKDIKIIDTSLTAAQLIRVIKYQLELKKIEGSISKVDIDEEFGLISGVIPSKFANGRKLKFKIEVIDLINSSSLHVIKMKGNDKGFQSLVNIVTFIIKKEEQDKICRR
What is the function of this protein?
Protein kinase involved in determination of morphology during the cell cycle of both yeast-form and hyphal cells via regulation of SWE1 and CDC28.  Regulates pseudohypha formation, but is not required for septin ring organization or septum formation.  Plays an essential role in virulence in a mouse model.
What are the official names of this protein?
Serine/threonine-protein kinase HSL1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.
What are the subcellular locations of this protein?
Bud neck. Note=In the hyphal cells, localizes at a potent septation site before the completion of septum formation.
Protein: GLGB_BUTFI
Sequence: MSQKVFISEDDEYLFGQGTHYDIYDKLGAHPSEEKGKKGFFFAVWAPNAADVHVVGDFNGWDENAHQMKRSKTGNIWTLFIPGVAIGALYKFLITAQDGRKLYKADPYANYAELRPGNASRTTDLSGFKWSDSKWYESLKGKDMNRQPIAIYECHIGSWMKHPDGTEDGFYTYRQFADRIVEYLKEMKYTHIELIGIAEHPFDGSWGYQVTGYYAPTARYGEPTDFMYLINQLHKHGIGVILDWVPAHFCPDEFGLACFDGTCIYEDPDPRKGEHPDWGTKIFNLAKPEVKNFLIANALYWIRKFHIDGLRVDAVASMLYLDYGKKDGQWVPNKYGDNKNLDAIEFFKHFNSVVRGTYPNILTIAEESTAWPKVTAPPEEDGLGFAFKWNMGWMHDFCEYMKLDPYFRQGAHYMMTFAMSYNDSENYILPLSHDEVVHLKCSMVEKMPGYKVDKYANLRVGYTYMFGHSGKKLLFMGQDFGQEREWSEKRELDWFLLENDLNRGMKDYVGKLLEIYRKYPALYEVDNDWGGFEWINADDKERSTYSFYRRASNGKDNILFVLNMTPMERKGFKVGVPFDGTYTKILDSAKECYGGSGSSVPDKIKAVKGLCDYKDYSIEFDLPPYGAEVFVFQTKKTKN
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RSMF_SALA4
Sequence: MAQHAVYFPDAFLTQMREAMPSTLSFDEFISACQRPLRRSIRINTLKISVADFLALIAPYGWSLTPIPWCHEGFWIERDDEEALPLGSTAEHLSGLFYIQEASSMLPVAALFADDNHPQRVMDMAAAPGSKTTQIAARMGNRGAILANEFSASRVKVLHANISRCGIANTALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNLDIAATQRELLDSAFHALRPGGTLVYSTCTLNRQENEEVCLWLKETYADAVEFLPLDDLFPDADRALTPEGFLHVFPQIYDCEGFFVARLRKISSLPAMPAPGYKVGTFPFTPLKGREALHVTQAANAVGLLWDENLHLWQREKEVWLFPAEIESLIGKVRFSRLGIKLAESHNKGYRWQHEATIALACPTHAHAFELSAQEAEEWYRGRDIYPQTPPAADDVLVTFQRQPLGLAKRIGSRIKNSYPRELVRDGKLFTGNS
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIAF1_DROME
Sequence: MQDPNEDTEWNDVLRAKGIIGPKAKEAEITEDQIQKLMDDAIQRRTDLPLNEGQRDKKIDDMSLDELDELEDSEDEAVLEQYRQRRIAEMRATAEKARFGSVREISGQDYVNEVTKAGEGIWVVLHLYANGVPLCALIHHHMQQLAVRFPQTKFVRSVATTCIPNFPEKNLPTIFIYHEGALRKQYIGPLELRGDKLTAEELEFMLGQAGAVPTEITEDPRPQIRDKMLADLEDKSSDFY
What is the function of this protein?
Modulates the activation of caspases during apoptosis.
What are the official names of this protein?
Viral IAP-associated factor homolog.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAE_BORPE
Sequence: MAAVQVRRRGRALALALWAGFALSVGGGVRARDGLATPPAFEGQAAPAVSWPCPPPADRLDDLALLEAIDLALCHSPALRQGWARIKARSAEVGLARAPYYPSVALSAGRSAQRRSTGLGEDGVRNNVMAVTLAWRLFDSGARSAALRAAQAQLDEAAQAYGAVLQDKLAEVVGAYYEAATARQALHTAVEDTEIARRSASIAARRARAGLDSHGDVLHAQAALERARLAQAQAEGAQARALAGLAQVLGVDPATPIVLAPGPLAPQRIEDRELAQWLRDARQRHPAIKAAQAGLAAATAQVDVARATDMPTVDLSLGHYRNSSENVSVFAGSSRSVSASLNLRIPLFDGFARRHRIQGARAEVQRQEALLDQARLATGAAVARAYADLRAARASHEASLRWLKAARAAYESDLRRYEAGVGGVAELLRAQSDWLSARQRHVLYAAQLRTRALALLAAAGELGRSTIDGDPPKE
What is the function of this protein?
CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).
What are the official names of this protein?
Protein CyaE.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: HIS7_ANADE
Sequence: MTRRAAVKAPRAGAAARRGSVARRTKETDVAVDLRLEPGEASISTGLPFFDHMLDQISRHGGMALTVRAEGDLQVDAHHTVEDVGIGLGEALRQALEDKAGLARYGHAVVPLDEALVEAVVDLSGRPHLTFNAKLPSGKKFIGGYDVDLTQDFLQALVNHARICVHVNVRYGRNLHHVVEAIFKATARALRAATAREGTALPSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_CHLFF
Sequence: MPSRVLITSALPYANGPLHFGHIAGAYLPADVYARFRRLLGDDVLYICGSDEYGIAITLNAERAGLGYQEYVNMYHKIHKDTFDKLKISLDFFSRTTNPFHKALVEDFYTQLKSKGLIENQTSLQLYSEEENRFLADRYVEGTCPRCGFDGARGDECQKCGADYEATDLIHPRSKLSGSELVLKETEHAYFHLERMVEPLLDFIDKSYLPEHVRKFIVDYIKNLRPRAITRDLSWGIPVPDFPNKVFYVWFDAPIGYISGTMDWAASVNNPEAWKDFWLEESTEYVQFIGKDNIPFHAAIFPAMELGQSIPYKKMDALISSEFYLLEGAQFSKSEGNYIDMDAFLDTYSLDKLRYVLAATAPETSDSEFTFLDFKTRCNSELVGKFGNFINRVLAFAEKNGFKELVYSETLLEDKDKKFLDDAQRIVQEAREHYSKYSLRKACSAIMELAALGNIYVNDQAPWKLLKEGLAHRVEAVLFCACYCQKLLALISYPILPGTAWEIWNMLSPKSLDLVNQDKDRVKNLWNSEFFDVSDEVFSLKTPQLLCAIVD
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y914_MYCBO
Sequence: MRALLAQNRLVTLCGTGGVGKTRLAIQIASASELRDGLCFVDLAPITESGIVAATAARAVGLPDQPGRSTMDSLRRFIGNRRMLMVLDNCEHLLDACAALVVELLGACPELTILATSREPIGMAGEITWRVPSMSITDEAVELFADRASRVQPGFTIANHNAAAVGEICRRLDGIPLAIEFAAARVRSMSPLEIADGLDDCFRLLAGGVRGAVQRQQTLRASIDWSHALLTETEQILFRRLAPFVGGFDLAAVRAVAAGSDLDPFSVLDQLTLLVDKSLVVADDCQGRTRYRLLETVRRYALEKLGDSGEADVHARHRDYYTALAASLNTPADNDHQRLVARAETEIDNLRAAFAWSRENGHITEALQLASSLQPIWFGRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLSTWLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECRDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEALELSREITAEAEASNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIGYAAMTYAALAAGDVTAALEASDAARPILRAQPDQVTMHQVLMAQLALAGGDAIAARQFANDAVDATNGWHRMVALTIRARVATARGEPELARDDAHAALACGAELHIYQGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALRQQTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQRGRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQTHLTHVYAKLGLASRVQLVDEAARRGSPS
What are the official names of this protein?
Putative HTH-type transcriptional regulator Mb0914c.
Protein: CT13_RANCI
Sequence: GLFDIIKKVASVIGGL
What is the function of this protein?
Bacteriostatic action for Gram-positive bacteria.
What are the official names of this protein?
Citropin-1.3.
What are the subcellular locations of this protein?
Secreted.
Protein: TF2LX_PONPY
Sequence: MEATADGPAETQSPVEKDSPVKTQSPAQDTSITSRNNADRGRVLALPEHKKKRHGNLPAKSVKILRDWMYKHRFRAYPSEEEKQMLSEKTNLSLLQVSNWFINARRRILPDMLQQCGNDPVIGHKMGKNAHATHLQSTDASVPASSGPSGPDNVQSLPLWPLPKGQMSGEKLPDPESAPSQKLTGKAQPEKKVKFSITSPFSPEPVSPEEYADFSSFQLLVDAAVQRAAELELEKKQDPNP
What is the function of this protein?
May have a transcription role in testis.
What are the official names of this protein?
Homeobox protein TGIF2LX, TGF-beta-induced transcription factor 2-like protein, TGFB-induced factor 2-like protein, X-linked, TGIF-like on the X.
What is the protein family that this protein belongs to?
Belongs to the TALE/TGIF homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BIOB_MARMS
Sequence: MSINNISAPRFDWTHAEIKALFDLPFMDLMFRAQTVHRENFAPNEVQVSTLLSIKTGACPEDCKYCPQSGHYNTELEKEKLMEVQKVLEEAALAKEKGASRFCMGAAWKHPSEKDFPYVLEMIKGVKSLGLESCVTLGSLNDDQAKRLSEVGLDYYNHNLDTSAEFYDSIITTRTYQDRLDTLSRVRDSGIKLCCGGIMGMGEEQKDRVGLLRQLSQMTPHPESVPINMLVKVEGTPLENVDDLDTFEFIRTIAVARILMPKSHVRLSAGRQGMNEQTQALCFMAGANSIFYGEKLLTTGNPEADKDMALFANLGINPEKREEHSDAAVAEAIAAQVVKQEESKLFYEASV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: YIDC_FRATF
Sequence: MKANHIRILLLVTIAIMFISLMGKWEQTFPADNTKQQTSATQNNSHYDNADSSTNTDVTITDAKSSLAKETNFSKYDNAKSITINTVVFKDVKVSLLDGAIISASLKDYSISLDDKTPMSLLTDKSGSEYIAKSTIVVNKQPISVNFEDQGIKIENSKQILTLTGSADGLQITRTYTFDDTKYNISVSQNIKNTTSAPVNVIVDDSFARDFDPAGDSFSLLNAHSYTFTGVAYSTAKDSFRKESFKDISKTNGQPTVINSDGQGWVAFLQHYFVSAWIPQSTNAKIYYKNLNGDVFEAGAFTGATIAPNQSENISSILYTGPIIKANLVDLAPNLEKTLDYGMLSFFSEIIFWVMNHIHSLVGNWGLAIILVTCLIKLIFYPLSAKSYRSMAKMRMLQPRIKRLQETYKDDRQALGKKMMELYKEEKVNPLSGCLPMLIQIPIFISLYWVLLESVELRQAPFIFWIHDLSMKDPYFVLPVLMGLSMFLQQKLSPAPADPMQAKVMMFLPVIFTFLFASFPSGLVLYWLTNNLISISQQWIITRHYQATHKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MLO13_ARATH
Sequence: MAEARSGSLEYTPTWVVAFICFIIVLLSLLAERGLHHLGKCLKRRQQDALFEALQKLKEELMLLGFISLMLTVSQAAIRHICVPPALVNNMFPCKKPLEEHHAPKSSHSIINNARHLLSTGESPDHCAAKGQVPLVSVEALHQLHIFIFVLAVFHVIFCASTMVLGGARIQQWKHWEDWFKKRPSQKGTTRRGHHAHAHELFSANHEFFEMHAGGFWRRSVVISWVRSFFKQFYGSVTKSEYIALRQAFIMSHCRTNPSFDFHKYMLRTLEIDFKKVVSISWYLWLFVVVFLLLNVGGWNTYFWLSFLPLILLLMVGAKLEYIISSLALDVSEKRSRAEEAVITPSDELFWFHRPGIVLQLIHFILFQNSFEIAFFFWILFTYGIHSCIMEKLGYLIPRLVMGVLVQVLCSYSTLPLYALVTQMGSKFKKGIFDNVVQSTLEGWLEDTRNRGESTSEAHRIEMQPTTPESYNVQSENP
What is the function of this protein?
May be involved in modulation of pathogen defense and leaf cell death.  Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity).
What are the official names of this protein?
MLO-like protein 13, AtMlo13, AtMlo20.
What is the protein family that this protein belongs to?
Belongs to the MLO family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HUTH_RUEPO
Sequence: MTALTLTPGSATLEHLARIYFDESPVRLDPACRPAVEAAAARIRAAAAGDVPVYGVNTGFGKLASLKVAPQDTATLQRNLILSHCCGVGAPIPRRMARLMMVLKLLSLGRGASGVRWELITLLQEMLARDVTPVIPVQGSVGASGDLAPLAHMTAVIIGAGEAEYQGQRLPGAEALARAGLTPIALGPKEGLAFINGTQFSTAFALAGLFGAWRAATSSLVTAALSTDAIMGSTAPLQPEIHALRGHRGQIDAAARMRALLDGSEIRESHREGDTRVQDPYCIRCQPQVTGAAMDVLRQAAQTLEIEANAATDNPLVLAEADMIVSGGNFHAEPVGFAADLIALALSEIGAIAQRRVALMVDPTLSFDLPPFLTPKPGLNSGLMIAEVTTAALMSENKHLANPCVTDSTPTSANQEDHVSMAAHGAVRLGRMVENLHYILGVELLCAAQGIEFRAPLQTSTALQAAVARLRAEVPRLEEDRYMAPEIETAARLVGAGALLDVVGIDMGGLRP
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_STRPJ
Sequence: MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAYGHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVEGIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSDRIPREYY
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: TAF6L_HUMAN
Sequence: MSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPMRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYHQVTRAVLGDDPQLMKVALQDLQTNSKIGALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLFRNPHLCLGPYVRCLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQHILLSLQKILADPVRPLCCHYGAVVGLHALGWKAVERVLYPHLSTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGPGGRGCRRLDDLPWDSLLFQESSSGGGAEPSFGSGLPLPPGGAGPEDPSLSVTLADIYRELYAFFGDSLATRFGTGQPAPTAPRPPGDKKEPAAAPDSVRKMPQLTASAIVSPHGDESPRGSGGGGPASASGPAASESRPLPRVHRARGAPRQQGPGTGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTSRPARRWALSDYSLYLPL
What is the function of this protein?
Functions as a component of the PCAF complex.  The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context.  The PCAF complex could be considered as the human version of the yeast SAGA complex (Probable).  With TAF5L, acts as an epigenetic regulator essential for somatic reprogramming.  Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state.  Functions with MYC to activate target gene expression through RNA polymerase II pause release (By similarity).
What are the official names of this protein?
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L, TAF6L, PCAF-associated factor 65-alpha, PAF65-alpha.
What is the protein family that this protein belongs to?
Belongs to the TAF6 family.
Protein: ACDG_ARCFU
Sequence: MKVKSPLEVYNYLPRTNCGECGFDTCMSFAAHILDRSVTPLDCKPLVRDAEKDPKVKKKLEELLELTAPEIAEVVIGVGENAVKIGGEEVLHRHELTFFNPTGFFYDVWDTMDDKALEERCDRVVSYKKFYVGNFLTLDGFAVRCTSGDPKRYREVVKKVASYGKPLILVALDSECMKAALEEVADQRPLMYAATEGNWKEFLKLALEYKVPVTLRAKDLDLLKSMAVTFKQAGVKDIVLDPVTEPLGEGLKGTFERVIQLRRTAIAGQDKDVAYPIMITPIAAWLIEGDDVTKSYWEAVIASIFIVKYGDVMIFRSIDQHVVMPTITLRFNIYTDPRTPVQVEPGLRAINDPGPDDPVFITTNFALTYYTVESDLTSGGIKGWLLVLNTEGLGVEVSVAGGQFTASKVKELIEETKIEEKVNHRYLVIPGLAARLQGAIEDETGWKVLVGPMDSGRIKGWLEKNWPPKE
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit gamma, ACDS complex subunit gamma, 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase, ACDS complex methyltransferase, Corrinoid/iron-sulfur component large subunit.
Protein: TI214_CITSI
Sequence: MIFQSFILGNLVSLCMKIINSVVVVGLYYGFMTTFSIGPSYLFLLRARVMEEGEEGTEKKVSATTGFIAGQLMMFISIYYAPLHLALGRPHTITVLALPYLLFHFFWNNPKHFFDYGSTTRNSMRNLSIQCVFLNNLIFQLFNHFLLPSSMLARLVNIYMFRCNNKMLFVTSSFVGWLIGHILFMKWVGLVLVWMQQKNSIRSNVLIRFNKYLVSELRNSMARIFSILLFITCIYYLGRIPSPIFTKKLKVKETSETEERDVEIEKTFERGGTKQGQEVSAEEDPSPSLFSEEKEDPDKIEETEEIRVNGKEKKKTKHEFHLRFKETCDKNSPVYETSYLDGNQENSKFEIFQLFKEKKEEKYLLWFEKPLVTLLFDYKRWTRPLRYKKNNRFENAVRNEMSHYFFYACRSDGKERISFTYPASLSTFLDMIKKNNYFFATEKLSSDEFSTHWNYTNNQKIKNLSKEFRNRLEGLDKGSLIRDILEKRTQLCNDKTKKKYLPKTYDPLLNGPYRGRIKKFFSPPILNTTYIKNKIRTPWINKIHNLIFINDYHEFEQTIDRFNRKSFSSEEVRSLLTEREREHIDSEDRIKSLNFLFDAVITDPNDQKIRKKAIKEISKRVPRWSYKLIDNVYQELGEYDENVRGKHAFRSRKAKRLVVAVDHQTKGDVSLPHYLEQSDFRRYIIKGSMRAQRRKTVIWKPVQANAHSPLFLDRIDKTLYLSFDISQLMKVILRNWMVKNKNQKLSDYTNAKTRKLDKKEKKKLKGERYQRQEMVRIKQAEGWDKRLLTRILRSSMLVIQSILRKYIVLPLLIIAKNVVRILLFQDPEWSEDFKDWNREIYVKCTYSGVNLSETEFPKNWLIEGIQIKILFPFHLKPWHGSTIQSSHKDPKSEQETDVCFLTIFGLETDMPFGSPQKRRSFFEPIFKELKKKIRKLKTKSFIVLRDFKEGKIKELSKINLREIEKLRETQKNSIISKQMIHEPSIEISSMDWTKLSRTEKKMKDLTNRTSRIRNQIYKITKEKKKGSLTQETNISSNKPTYSVKILDPSKRIWRILKKRNARLIRKSYLFLKFGIEKIYRNIFISTLTIPRINTKPFRESTRKQMKIIEKNIHNNEANPERINKTNKNRIISTIQKLISKTSNKNSKISCNLLSFSQSQAYVFYKLLQVPILNFYNLRPVLQYHGTSLFLKNEIKDFFEKHGIFNYQLRHKPLWNFGRNTRKHCLSGHYQYDLSRIKWARLVPQEWRNRANQHCMAQNKDLIKRDSYEKNGLTHYEKQHFFEADLLRNQKSNFKKHYRYDLLSYKSLNYEDKKDSYIDRSLVQVNNKEEYYSNYNRKKVKLLAMLGSISINNYIGEDDIMDMEKFLYRKYFDWRILNFCLRNKANMEAWVDMDTGTSSNQNTRIGSNNYQKINAINNRVPFYLTIHQDEEINPSTQKGFFCDWMGMNEEILSCPISNPESWFFPEFVLLFNAYRTKPWIIPIKLLLFNFNGNSKKNRTGKKEADLFISPTQKEYFELSNQSKEENELADQGTPRSDAQKQVILGSVLSNQEKDGEENYTGSDMKTRIKKKQSKRETEVQLDFFLKRYLCLQLRWRGAVSFREKILNDMQVYCHLVRLINPSDVAIASIQRGEMSLPILITKKKFALKELTKGGMLIIEPRRLSVKNDGQFFLYQIVGIALVHKNKRKITKRYQEKGYVDKKDFDEFIAKHQKMTGNRNKNHYDLLVPETILLPKRRRELRTLICFNSKNQNGMQKNPVFFNNGKGGGRVLDKNKNLAREKNQLIQLKFFIWANSRLEDLICMNRYWFNTNNGSRFSMVRVHMYPRLKIR
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: ATPD_MESH2
Sequence: MYLYKKNYYGYAESLLDISISENNVEKYINDCFFILSIIQNNQVLILLFKSHFIGKQEKFNIIDKIFSAKIEKILVNFLKVIAKNNLFLYYKQILLKYIKLANSHLSQTWGEIQTAFPISSVMTSSFESILSKKLGKKVHLRHKINSKLISGIRIIVDNQIFENSLFSELKLLKQNLKKHLITKNDL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LOLD_LEPIC
Sequence: MQFVNSGISVTDLRKTFGNSEIIKGVTLDIEDGDYVSLTGKSGSGKSTLLYMISSLDPPSSGTIKIDKKDIYRMNEEEIHEFRNKRMGFIFQFHYLLPEFTAIENVLMPARKAGLLKEYQSYAEHLLEEFDLKDRMNYRINRLSGGQAQRVAIARALVMNPKYIFADEPTGALDSTNTKVVMNILEKVNRETKTTILVVTHDPDFASKTKRQIHLVDGRVVSLKEFEAIKKSAKTAR
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CP52W_CANAP
Sequence: MNINFSDALMLGGISLSFLLASQAIYFYFIYSPRAKKLGCAPPPIFFSFPLGIPDLIRLVNAWFHDDLLEWFTHRFEEFGRRTAFQSVAGQLWIGTIEPENIKTMLATSFKDYSLGFRYNAMYGLLGNGIFTLSGDGWKNSRALLRPQFSREQVSHLESMRTHINMMINNHFKGGQVVDAQVLYHNLTIDTATEFLFGESTNTLDPALAQQGLPGPKGLVTGEQFAEAFTSALELLSVRVMAGAAWFLVWTPKFWRSCKVCHNFIDYFVYKALATPMEKGQDADRYVFIRELTKETSDPRVIRDQALNILLAGRDTTAALLSFTTYYLGAYPEVYDELREAVIADFGSADAEPPTFEQLKQCKVLQNVIREVLRLHPNVPLNFREAIADTTFPTGGGPNGDQPIFVPKGQKVFYATYVMQRNAGIWGPDSTSFRPDRWNEPREALASGWDYIPFNGGPRICLGQQFALTEASYTLVRICQEFSRIEVLHPDVITARNVMKQRMRLPNSSSGGVITRFIR
What is the function of this protein?
Together with an NADPH cytochrome P450 the enzyme system catalyzes the terminal hydroxylation as the first step in the assimilation of alkanes and fatty acids.
What are the official names of this protein?
Cytochrome P450 52E2, CYPLIIE2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane. Membrane; Multi-pass membrane protein.
Protein: GUAA_BACMK
Sequence: MKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFELGLPIFGICYGMQLMTQHFGGKVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAGMSNEGENLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKDEAEGVMKTFSEGFHMNVIKVDAQERFMNKLKGVEDPEQKRKIIGNEFIYVFDDEASKLQGMDFLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGIRVLGEITEEKLEIVRESDAILREEIIKAGLDREVWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPWDVLEKISVRIVNEVKHVNRIVYDITSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: Y4HO_SINFN
Sequence: MLPSGQNVRVWIATGHTDMRCGFPSLALRVQEVLKLNPLDGNLFVFRGRSGSLLKVIWSDGQGSCLFTKRLDRGRFVWPSAEGGAIAISPAQLSYLLSGIDWRHPQETWRPTKVG
What are the official names of this protein?
Uncharacterized protein y4hO.
What is the protein family that this protein belongs to?
Belongs to the transposase 34 family.
Protein: MAMD1_HUMAN
Sequence: MDDWKSRLVIKSMLPHFAMVGNRQEPRKLQESGKKPSWMEEEDLSFLYKSSPGRKHQGTVKRRQEEDHFQFPDMADGGYPNKIKRPCLEDVTLAMGPGAHPSTACAELQVPPLTINPSPAAMGVAGQSLLLENNPMNGNIMGSPFVVPQTTEVGLKGPTVPYYEKINSVPAVDQELQELLEELTKIQDPSPNELDLEKILGTKPEEPLVLDHPQATLSTTPKPSVQMSHLESLASSKEFASSCSQVTGMSLQIPSSSTGISYSIPSTSKQIVSPSSSMAQSKSQVQAMLPVALPPLPVPQWHHAHQLKALAASKQGSATKQQGPTPSWSGLPPPGLSPPYRPVPSPHPPPLPLPPPPPPFSPQSLMVSCMSSNTLSGSTLRGSPNALLSSMTSSSNAALGPAMPYAPEKLPSPALTQQPQFGPQSSILANLMSSTIKTPQGHLMSALPASNPGPSPPYRPEKLSSPGLPQQSFTPQCSLIRSLTPTSNLLSQQQQQQQQQQQANVIFKPISSNSSKTLSMIMQQGMASSSPGATEPFTFGNTKPLSHFVSEPGPQKMPSMPTTSRQPSLLHYLQQPTPTQASSATASSTATATLQLQQQQQQQQQQPDHSSFLLQQMMQQPQRFQRSVASDSMPALPRQGCCHLFAWTSAASSVKPQHQHGNSFTSRQDPQPGDVSPSNITHVDKACKLGEARHPQVSLGRQPPSCQALGSESFLPGSSFAHELARVTSSYSTSEAAPWGSWDPKAWRQVPAPLLPSCDATARGTEIRSYGNDP
What is the function of this protein?
Transactivates the HES3 promoter independently of NOTCH proteins.  HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ.
What are the official names of this protein?
Mastermind-like domain-containing protein 1, F18, Protein CG1.
What is the protein family that this protein belongs to?
Belongs to the mastermind family.