PharMolix/UniProtQA huggingface dataset:
Protein: CHST_CAEEL
Sequence: MLKWFIISCCLLTAISYSTYYLFTSNSWIKTVKTHTYSRFYQLIKENTKTQLDRLQEEAKLSGKSLIPPFINFDREYAIAPKYNISICRIKKSMSTLMSGVACVLYDTGKFMRNNRSILEVWSHRFCGEKNEYRRMNEVKWRMGDAHHTFKKIVVIRDPIARFISFFSNKCIFEAQKYPDRKQCYNCQGNVTCFLEKQYERFVQHSSDYSRIRPSYEDKHAAPLSWNCEFGKFLKDYKIIKLAVDPKDRKNGLANLMNVLKESNVPNSTLRFIEKSALEGETMHATYDSDAHDVVKKEIENDKKIREWLKRIYYLDFVIFDFDTTFINS
What is the function of this protein?
Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residue of chondroitin.
What are the official names of this protein?
Carbohydrate sulfotransferase chst-1, Chondroitin 4-O-sulfotransferase, Chondroitin 4-sulfotransferase, C4S, C4ST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RPOZ_PORPU
Sequence: MNHHNSLDSSDITYKTEELLEATTNRYKITVQVANRAKRRKYEDVDIIDDPQIKPVIRAILEMVDEITQPEIISD
What is the function of this protein?
May be involved in RNA polymerase activity.
What are the official names of this protein?
Putative DNA-directed RNA polymerase subunit omega, PEP, Plastid-encoded RNA polymerase omega subunit, RNA polymerase omega subunit.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AMPA_TROWT
Sequence: MSDYTNTVTVEITSDDSLVADVIVVPVASGAVPRLPEDSKFRAYEDILQKLGVTGSKDELTRIPLDGSKHVVLAFIGVGKAFSATELMFAAGSAVRQIGARCIQIDFSVTQKDKLSAIVEGAFLGAYRFDKYRSKKSECPEVIRVSHNINGITDSECRQIIARAKVIAGSVGLAKDLVNTTGDDLYPAQFASFVAKDLEGIDHISVESWDEKRLQEKSCGGILGVGRGSNFPPRLVKISYTPGQYKKHLSLVGKGITFDTGGLSLKPASAMLGMKYDMTGAANVFAVLRIVALLRLSVRVTGWLCLAENMLSGSAIRPGDILRTYSGKTVEVTNTDAEGRLVLADGLALAGDERPDVIIDIATLTGAAKVALGESCSGLMGNNPDLLCSLEVAAKSVGEKFLAVPIDDDALQKALKSDIADIVNVPTSNKVPGMQFGAVFLKEFETTNDSGEAIPWAHLDVAGPANASYDTGFNSCGPTGVAVRSLVEFCRCLSSAPERKLF
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_LEPIC
Sequence: MASSTFFSDWNQMLKPRVTSLVLATIIPGLYLASEQSPSGFLIAITLFGTFLMSSASFIFNQVIEKDRDAKMKRTSNRPIPSGRISVVQATLVGIAMMGSSFYVLAVYVNLLTALCAFAALISYVFLYTIFLKPRTTQNIVIGGVAGCVGPLIGYAAIGNSLPVQAWSLFMMIFLWTPAHFWALAIFLKEEYSDADFPMLPVVKGIHQTTKSIFFYTILYSIACVSFYFLESSMGFLYLIVSLIVCIWMGILSYQLIQNPEPQSARKFFFFSILHLFIINITIVVDHLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGE_SHIDS
Sequence: MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKNLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDSLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCA_VIBCM
Sequence: MNRLYVGSEVGQLRRVLLNRPERALTHLTPSNCHELLFDDVLAVEAAGVEHDAFANTLRTQDVEVLLLHDLLEETLAIPEARQWLLNTQISDFRFGPTFARELRHALNHLDDHHLTTLLLGGLAFSELHLESDSMLPKMRQPLDFVIEPLPNHLFTRDTSCWVYGGVSLNPMMKPARQRETNHLRAIYRWHPIFAQHPFIHYFGIDDLHYDNANIEGGDVLVIGKGAVLIGMSERTSPQGVENLAAALFKHGQASKVIAINLPKHRSCMHLDTVMTHMDVDTFSVYPEVMRKDLPTWRLTPKGNNGDMRVEQVPSYLHAIEQALGVDYLKIITTGGNSYEAEREQWNDANNVLTVKPGVVIGYERNVYTNEKYDKAGIKVLTIPGNELGRGRGGARCMSCPIERDGI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TR07_CURCL
Sequence: MKLTVFSAKPYDIEYLGGIATNQNSSPAIEINFLHVPLSSETAAFANGADAVCVFVHDVLDANVLRELYAAGVRAILFRCSGYNNIDLREAERLGFFVANVPSYSPEAVAEFAVALIQTLNRKTHRAYNRVRDGNFNLDGLLGRTLHGKTVGIVGSGRIGLAMAQIVQGFGCKLLAYDPRPTEAFKKYGEYVDLDTLLSQCDIVSLHCPLMDSTQHIINDTTVSKMKRGAMLVNTSRGGLIDTQSVMKALKSKRLGGLALDVYEGERALFYKDHSGDIIHDDLLMRLTTFHNVVVSGHQAYFTEEALTEIAECTLRNLDDWAKGVPTANALVQGRNSNGRRERGLARL
What is the function of this protein?
Probable dehydrogenase; part of the gene cluster that mediates the biosynthesis of KK-1, a novel cyclic decapeptide compound with potent antifungal activity (PubMed:29686660).  The nonribosomal peptide synthetase (NRPS) catalyzes the elongation and cyclization of the decapeptide chain composed of 1 pipecolic acid residue (Pip), 1 alanine residue (Ala), 1 aspartic acid residue (Asp), 1 isoleucine residue (Ile), 1 glycine residue (Gly), 1 tyrosine residue (Tyr) and 4 valine residues (Val) (PubMed:29686660).  The Asp, Ile and 3 Val residues are N-methylated by the 5 methyltransferase domains from the NRPS (found in modules 3, 5, 6, 7 and 9), whereas the Tyr residue is O-methylated, probably by the cluster encoded O-methyltransferase OMT (PubMed:29686660).  The other tailoring enzymes from the cluster may be involved in further modifications leading to the synthesis of KK-1 (Probable).
What are the official names of this protein?
Probable dehydrogenase TR07, KK-1 biosynthesis cluster protein TR07.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: ILKAP_MOUSE
Sequence: MDLFGDLPEPERAPRPSAGKEAQGRPVLFEDLPPASSTDSGSGGPLLFDDLPPAASGNSGSLATSGSQVVKTEGKGAKRKAPEEEKNGGEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITQECNPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDIISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDDKIQTREGKPAVDARYEAACNRLANKAVQRGSADNVTVMVVRIGH
What is the function of this protein?
Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation.  Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling.  Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation (By similarity).
What are the official names of this protein?
Integrin-linked kinase-associated serine/threonine phosphatase 2C, ILKAP.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_THET8
Sequence: MKPKTLSPILTAKGVRLAIAVGRFNERVTKLLLEGALEAYARLGGDPAEVLVAWVPGSFELPLVAKRLAQRPDVDAVVALGAVIRGETPHFEYVAGQAASGLMQAMLQTEKPIVFGVLTTNTPEEAQERAGGKAGNKGAEAVFTAIEMVRLLEAISR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MNTP_XANCB
Sequence: MSPLSIVLLGFAMSTDAFAAAIGKGAAMRRPRWRDAVRAGLVFGCIEAITPVIGWMLGRAASDYLAAFDHWIAFGLLGALGAHMIVAGLRNESEVDEALRDTPKRYGLLALAATGFATSIDAMAVGVSLAFLDVHIGVVAAVVGLCTLSMVTAGVMLGRALGALIGKRTEILGGVILILIGSTILYEHLSGAA
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPP1_ARATH
Sequence: MLTTPTRFVALRIPFRSSNKIPISIAPSPKVFPRKPVIRVPASLRFVATMSTPAAAVNATVTVTDAGRGSITHVIFDMDGLLLDTEKFYTEVQEKILARYNKTFDWSLKAKMMGRKAIEAARLFVDESGISDSLSAEDFIVERESMLQDLFPTSDLMPGASRLLRHLHGKGIPICIATGTHTRHFDLKTQRHRELFSLMHHVVRGDDPEVKEGKPAPDGFLAASRRFEDGPVDPRKVLVFEDAPSGVQAAKNAGMNVIMVPDSRLDKSYCNVADQVLASLLDFKPEEWGLPSFQDSHN
What is the function of this protein?
Acts as a glycerol-3-phosphatase with higher stereospecificity for L-glycerol-3-phosphate than DL-glycerol-3-phosphate (PubMed:17136424).  Can also dephosphorylate in vitro 5-amino-6-(5-phospho-D-ribitylamino)uracil, also known as ARPP (PubMed:27490826).
What are the official names of this protein?
(DL)-glycerol-3-phosphatase 1, mitochondrial, 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase, AtGpp1/PyrP3, 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate phosphatase, ARPP phosphatase, Glycerol-1-phosphatase 1, AtGPP1, Haloacid dehalogenase-like hydrolase domain-containing protein GPP1.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. DOG/GPP family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IF2_STRPN
Sequence: MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAAKIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAAPKASAEKKAEKSEPVKPAVAKEEAKPAEPVTPKTEKVAAKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDITILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAYVMEEIKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_XANOR
Sequence: MDRIALMNAPGTDWSAWPAPAKLNLFLQITGRRADGYHLLQTVFRLLDWGDTIHLRVRSDGQILRIGESLPGVAEDDDLVIRAARLLQSAAGAAAGAEIRVDKRIPAGGGFGGGSSDAATVLVALNALWGLALTADTLAELGLQLGADVPVFVRGRNAWAEGVGEQLTPIALPEAAYLLVDPGVHVPTPVLFRSQELTRDAAPAKITDFASGSLLDNAFEPVLRRREPAVEAVFQALSRVGTPRLTGSGSGCFVEFATRAAAEQALAQLPGSLRAWVVEGAAHSPLLDARDAMKV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: GLSA_STRAW
Sequence: MVIMSASWSSHAFQPVLERIADEIERTPGRGRPADYIPALAACDPRRFGMAVAELDGTVYGVGDWRQPFSTQSITKVFTLALDLAREGDALWEHVGREPSGNPFNSLVQLEYESGIPRNPFINAGALVVTDRLQTQTGDAAGSLLEFLRAESGNPRLTFDQDVAASEAAHGDRNAALGHFMASYGNIDNSVPVLLDQYFRQCSIEASCADLALATGFLARHGIRADGSRLLTQSQAKQVNAVMLTCGTYDAAGDFAYRVGLPGKSGVGGGIIAVVPGRCTLCVWSPGLDERGNSVAGVAALDRFTTLTGVSVF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: CDK5_DROME
Sequence: MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTDSSSSGH
What is the function of this protein?
Probably involved in the control of the cell cycle.  Interacts with D1 and D3-type G1 cyclins.  Possible regulator of neuronal differentiation and/or development (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 5 homolog, Cell division protein kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: AXIN1_HUMAN
Sequence: MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
What is the function of this protein?
Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling (PubMed:12192039, PubMed:27098453, PubMed:28829046).  Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway (PubMed:12192039).  In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B (PubMed:12192039).  Likely to function as a tumor suppressor.  Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7 (PubMed:16601693).  Also a component of the AXIN1-HIPK2-TP53 complex which controls cell growth, apoptosis and development (PubMed:17210684).  Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation (PubMed:17210684).
What are the official names of this protein?
Axin-1, Axis inhibition protein 1, hAxin.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane. Cell membrane. Note=MACF1 is required for its translocation to cell membrane (By similarity). On UV irradiation, translocates to the nucleus and colocalizes with DAAX (PubMed:17210684).
Protein: T2FA_DROME
Sequence: MSSASKSTPSAASGSSTSAAAAAAASVASGSASSSANVQEFKIRVPKMPKKHHVMRFNATLNVDFAQWRNVKLERENNMKEFRGMEEDQPKFGAGSEYNRDQREEARRKKFGIIARKYRPEAQPWILKVGGKTGKKFKGIREGGVGENAAFYVFTHAPDGAIEAYPLTEWYNFQPIQRYKSLSAEEAEQEFGRRKKVMNYFSLMLRKRLRGDEEEEQDPEEAKLIKAATKKSKELKITDMDEWIDSEDESDSEDEEDKKKKEQEDSDDGKAKGKGKKGADKKKKKRDVDDEAFEESDDGDEEGREMDYDTSSSEDEPDPEAKVDKDMKGVAEEDALRKLLTSDEEEDDEKKSDESDKEDADGEKKKKDKGKDEVSKDKKKKKPTKDDKKGKSNGSGDSSTDFSSDSTDSEDDLSNGPPKKKVVVKDKDKEKEKEKESAASSKVIASSSNANKSRSATPTLSTDASKRKMNSLPSDLTASDTSNSPTSTPAKRPKNEISTSLPTSFSGGKVEDYGITEEAVRRYLKRKPLTATELLTKFKNKKTPVSSDRLVETMTKILKKINPVKHTIQGKMYLWIK
What is the function of this protein?
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.  It promotes transcription elongation.
What are the official names of this protein?
General transcription factor IIF subunit 1, Transcription factor 5 large chain, TF5A, Transcription initiation factor IIF subunit alpha, TFIIF-alpha.
What is the protein family that this protein belongs to?
Belongs to the TFIIF alpha subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ECTC_BRADU
Sequence: MIVRSLHDIEATDHFVDWGNSTSHRLLTDKDGMGFSICHTIVRANTVSLLQYRNHLEACFCIGGEGEVEDMDGNVFPIRRGDMYVLDKHDKHLLRGGPDKDMILVSIFNPPLTGTERHKLDDPAGSTY
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: HSLU_EXIS2
Sequence: MHEFTPRQIVEKLNEHVIGQADAKRAVAIALRNRYRRQLLDPSLRDEVTPKNILMIGPTGVGKTEIARRLAKLVRAPFVKIEATKFTEVGYVGRDVESMVRDLVEASLRLVKDEKKEALKERAEAVANERIVDALVGKKASTGLGGGNPFEMLFGGTQKPPEQETANDTADRSVIRQQLFQGQLEDRMIDVDIEERQMDLFSGQQGMEGLANLQDMLGQVMPKKTKKRQLSVKEARPILTAEEAERLLDLNEVHDEAVRRAEQMGIIFVDEIDKIATKGQDSAGVSREGVQRDILPIVEGSTVVTKYGPVKTDHMLFIAAGAFHMAKPSDLIPELQGRFPIRVELDSLTEDDFVKILTEPNQALLKQYKALLGAEQVHVTFTEDAIRQIARIAAQVNDETDNIGARRLYTIMERVLEELSFEAAEMPETDVTITPQYVMDRVGKVADDRDLSQFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_RUEST
Sequence: MSDGRGNLELDVSRETLERLMVFSEVLKKWNPKINLVSRKSIDDLWTRHILDSIQVFDAAPEGGAWLDIGSGGGLPGIIVAILAAEKSPDTRITLMESDLRKCAFLRNAARECGVSVTVKSKRIESAPEENCDVLSARALADLDNLLGFAERHLAENGTAMFPKGANWKKEVDNARKRWRFECDEITSVTEPGAVILKIKGVERV
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAOX_COLLI
Sequence: MKKGYEVLRDPHLNKGMAFTLEERQQLNIHGLLPPCFLGQDAQVYSILKNFERLTSDLDRYILLMSLQDRNEKLFYKVLTSDIERFMPIVYTPTVGLACQHYGLAFRRPRGLFITIHDRGHIATMLQSWPESVIKAIVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVKPHQCLPVMLDVGTDNETLLKDPLYIGLRHKRIRGQAYDDLLDEFMEAVTSRYGMNCLIQFEDFANANAFRLLHKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNRLSDHTVLFQGAGEAALGIANLIVMAMQKEGVSKEEAIKRIWMVDSKGLIVKGRASLTPEKEHFAHEHCEMKNLEDIVKDIKPTVLIGVAAIGGAFTQQILQDMAAFNKRPIIFALSNPTSKAECTAEQLYKYTEGRGIFASGSPFDPVTLPSGQTLYPGQGNNSYVFPGVALGVISCGLKHIGDDVFLTTAEVIAQEVSEENLQEGRLYPPLVTIQQVSLKIAVRIAKEAYRNNTASTYPQPEDLEAFIRSQVYSTDYNCFVADSYTWPEEAMKVKL
What are the official names of this protein?
NADP-dependent malic enzyme, NADP-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBLP_CANAL
Sequence: MADQEVLVLRGTLEGHNGWVTSLATTPAHPDLLLSGSRDKTLIKWKLTGGEDNQYGIPKKSFKGHSHIVQDVTISADGAYALSASWDRTLRLWDLETGETTQRFVGHKGDVLSVSIAKNLRQIVSASRDKTVKVWNTIGECMATLTGHNDWVSAVRISPSDQSSTVISASWDKTVKSWDLADYSVNADFIGHTGYISCITLSPDGSLCASAGKDGVIILWDLNKNKTLYTLEAKAEVHALAFSPNRYWLAAATTSGIKIFKLQERSLLDELKPEFAVGATAKDPEAISLAWSADGQNLFAGYTDNVIRVWQVMTPSA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable).  Located at the head of the 40S ribosomal subunit in the vicinity of the mRNA exit channel, it serves as a scaffold protein that can recruit other proteins to the ribosome (By similarity).  Involved in the negative regulation of translation of a specific subset of proteins (By similarity).  Plays a role in morphogenesis and pathogenesis (PubMed:20929924).
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-like protein, 40S ribosomal protein ASC1, Absence of growth suppressor of Cyp1 protein 1, Cytoplasmic antigenic protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
Protein: CBF5_SCHPO
Sequence: MTDTHPGVDFMIKPEATSASKIDTAEWPLLLKNFDKLLVRTGHYTPIPCGNNPLKRPIAEYVSSGVINLDKPANPSSHEVVAWVKKILRVEKTGHSGTLDPKVTGCLIICNDRATRLVKSQQSAGKEYVCVLRLHDSVEGERNVASAIETLTGALFQRPPLISAVKRQLRIRSIYESKLIEFDNERNLAVFWASCEAGTYMRTLCVHLGLLLGVGGHMQELRRVRSGCLSENDDIVTMHDVLDAQWIYDNTRDESYLRRVIRPLESLLVGYKRIVVKDSAVNAICYGAKLMIPGLLRYEAGIEVNEEIVLITTKGEAIAVGIAQMSTVELSTCDHGVVAKVKRCIMERDVYPRRWGLGPQSMKKKTLKKEGKLDKYGRPNENTPADWSKSYIDYSDPNAEVAKPAPVVAPAAPTVEAEVNGVEDSKKRKSVESSEKDEDEAAKKEEKRRKKEAKKEKKEKKEKKEKKEKKKKSE
What is the function of this protein?
Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs and play a central role in ribosomal RNA processing.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  Catalyzes pseudouridylation at position 93 in U2 snRNA.  Also catalyzes pseudouridylation of mRNAs; H/ACA-type snoRNAs probably guide pseudouridylation of mRNAs.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit cbf5, Centromere-binding factor 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.