PharMolix/UniProtQA huggingface dataset:
Protein: STXB3_MOUSE
Sequence: MAPPVSERGLKSVVWRKIKTAVFDDCRKEGEWKIMLLDEFTTKLLSSCCKMTDLLEEGITVIENIYKNREPVRQMKALYFISPTPKSVDCFLRDFGSKSEKKYKAAYIYFTDFCPDSLFNKIKASCSKSIRRCKEINISFIPQESQVYTLDVPDAFYYCYSPDPSNASRKEVVMEAMAEQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKGLIKGKTQSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAVLEEDDDLWVRVRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQISKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQRVKDSMLVLLPVLLNKNHDNCDKIRAVLLYIFGINGTTEENLDRLIHNVKIEDDSDMIRNWSHLGVPIVPPSQQAKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSRCPAVWNGSGAVSARQKPRTNYLELDRKNGSRLIIFVIGGITYSEMRCAYEVSQAHKSCEVIIGSTHILTPRKLLDDIKMLNKSKDKVSFKDE
What is the function of this protein?
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
What are the official names of this protein?
Syntaxin-binding protein 3, MUNC-18-3, Mammalian homolog of Unc-18c, Munc-18c, Protein unc-18 homolog 3, Unc18-3, Protein unc-18 homolog C, Unc-18C.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated (By similarity).
Protein: IDIA_THEVB
Sequence: MEKVGRRVFLGMGAAATAYVTHHLWNQNAESSYAQQSSGGVINVYSARHYDTDKALYNTFTQQTGIRVNIIEAEADALIERIRSEGSRTPADVLITVDAGRLWRAQEAGILQPIQSRVLNSVVPANLREPQGHWFGLSRRVRVLIYNKSRVNPSQLSTYEDLANPKWRRQILTRSSSNIYNQSLTGSLLAIHGAQKTEQWARGLVQNFARPPEGNDTAQIRACAEGVGSVAIANHYYLARLIASDKEQDRAVAAKVGLFFPNQRDRGAHVNISGAGVVAGAPNRQGAIRFLEYLVSPKAQEMFAMANFEYPVRAGVPVHPIVKQFGNFRGQNVNAAVFGRNNAEALRIMDRAGWR
What is the function of this protein?
May also be part of a periplasmic ABC transporter complex involved in iron import.
What are the official names of this protein?
Iron deficiency-induced protein A.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: Y973_SYNJA
Sequence: MALWIYVVPPLAGLVIGYFTNDIAIKMLFRPYRAYRIFGWRIPFTPGLIPQNQPRLAKQIAKTIMGSLLTPEELHNLARKLLRTERMQAGIRWLLGVALDRLQNPEQQQQTAQVLARILADLFNESLPRLVKVLARQETFLEGPINQLFDQVLLELRLNAEQARQLSEWILKQALPPKVLRQNLVDFLTDRNIEALDEEFRERATGSYWLVANLFGLKNALLRLRTYCLEEPEGAEAILEDLLKDINAPRRLTEILQNLSLQNLPVSAVRQLRRALRDGIQDYLRSQGPEVIKGLGESIDWEKVASLVLGRLRNSKALIASIDQISADLALILERYLERDLESLMMQVIPVLNLDQVIADKVNATSPAELEQAIQQIVRQELQAIVNLGGLLGFLVGCVQVLFLLR
What are the official names of this protein?
UPF0754 membrane protein CYA_0973.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: O3621_CONAE
Sequence: MSRLGIMVLTLLLLVFIVTSHQDAGEKQATQRNAINFRWRRSFTRRAATEECEEYCEDEEKTCCGLEDGEPVCATTCLG
What are the official names of this protein?
Conotoxin ArMSGL-0121.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O3 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAB_RICAH
Sequence: MSKNLYIKTYGCQMNVYDSVKMQDLLYPFGYEPTENIEEADVIILNTCHIREKAAEKTYSELGRIKKLQDTRKKQGLNSAIIVVAGCVAQAEGEEIFTRTPYVDIVVGPQSYYNLPELISKIVRHAKHLIDLDFVEEAKFDNLPEQLYPQGASSFISVQEGCDKFCTFCVVPYTRGAEFSRNVEQVYREALQVVSGGAKEIMLLGQNVNAYNWKGSADKIFSLADLLKHLAQIPNLERLRYMTSHPIDMTDDLIQLHGTEPKLMPFLHLPVQSGSNKILKAMNRKHDREYYFDIINRLREARPDIVLSSDFIVGFPGETDEDFEDTLDLVRRVKYGQCYSFKYSPRPGTPGATRTDQIPEHIKSERLTILQKELMDQQLACNESCVGSTIKVLFDRSGKFDDQIIGKTIYMQSVYIQNPNKSLLGKIIDVKITKASLNSLTGEIL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDL1_ARATH
Sequence: MAPSTKVLSLLLLYVVVSLASGDESIINDHLQLPSDGKWRTDEEVRSIYLQWSAEHGKTNNNNNGIINDQDKRFNIFKDNLRFIDLHNEDNKNATYKLGLTKFTDLTNDEYRKLYLGARTEPARRIAKAKNVNQKYSAAVNGKEVPETVDWRQKGAVNPIKDQGTCGSCWAFSTTAAVEGINKIVTGELISLSEQELVDCDKSYNQGCNGGLMDYAFQFIMKNGGLNTEKDYPYRGFGGKCNSFLKNSRVVSIDGYEDVPTKDETALKKAISYQPVSVAIEAGGRIFQHYQSGIFTGSCGTNLDHAVVAVGYGSENGVDYWIVRNSWGPRWGEEGYIRMERNLAASKSGKCGIAVEASYPVKYSPNPVRGNTISSV
What is the function of this protein?
Probable thiol protease.
What are the official names of this protein?
Germination-specific cysteine protease 1, RD21A-like protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: MINC_GEOTN
Sequence: MAKQKQQYVTIKGTKDGLTLYLDDRCSYDDLMKEIEERLVKRSSVAANSPLVSVHLKVGNRYLTPAQEEELRALIRRSKNLVVDSIESNVISKAEAIEWVQKTEIVTVSRIVRSGQVLHVEGDLLLLGDVNPGGTVIAGGNIFILGALRGIAHAGYAGNKEAIIAASVMKPMQLRIGDVMNRAPDYKTDERNEMECAYINEHNQIVVDRLQLLMHLRPNLTRLERRM
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: CSTP1_RAT
Sequence: MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENKEDISQYGIARFFTEYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLESVAAIYQDLLSGKNPNTVIVPTSSSGQHRQRPALGDAGMLDGVEASLFCQRLENLCDRHKYSCPPPALVKEILSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLLVQVPGLVNSITATSEASCLPSRTPPRVGSPWKPLHRSRKLDAESDGSTEETDESET
What is the function of this protein?
Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly.  Regulates the assembly and stability of the TPGC and thereby modulates polyglutamylation of the microtubule, which antagonizes MAP4 binding.
What are the official names of this protein?
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1.
What is the protein family that this protein belongs to?
Belongs to the CSTPP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Protein: RHAB_ECOL5
Sequence: MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQNGYVTWNVDRLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTIYQLRALTEQQPELIPHIAHALLIPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINPNDDRFINPDEMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHIVGGGCQNALLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: TRHBN_SYNY3
Sequence: MSTLYEKLGGTTAVDLAVDKFYERVLQDDRIKHFFADVDMAKQRAHQKAFLTYAFGGTDKYDGRYMREAHKELVENHGLNGEHFDAVAEDLLATLKEMGVPEDLIAEVAAVAGAPAHKRDVLNQ
What is the function of this protein?
Forms a very stable complex with oxygen.  The oxygen dissociation rate is 0. 011 sec(-1).
What are the official names of this protein?
Group 1 truncated hemoglobin GlbN, Truncated Hb, trHbN, Cyanoglobin, Hemoglobin, Hb, SynHb.
What is the protein family that this protein belongs to?
Belongs to the truncated hemoglobin family. Group I subfamily.
Protein: MSRA_XANC5
Sequence: MLGIGAFKQRMPRPGEALPGREQALPLHNTHLVNGHPLRGEFIGLAQVQFGLGCFWGAERKFWNVPGVYTTAVGYAGGQTPNATYSEVCSGQTGHTEAVLVVFDEQAVSFAQLLRTFWESHDPTQGMQQGNDVGTQYRSAIYCTTQAQYDAALASRDAYQQQLTAAGYGAITTEIRFPAPTFYYAEDDHQQYLAKHPNGYCGLGGTGVSCPIGLDA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: AROB_XYLFT
Sequence: MTTPTPLRSVTVNTPPPYTIAIGPGLLHDPPRLAATIRGRHALILSDSEVAPRYAAQLHETLLRARPDLHLNVFTLPAGETSKSLENFGAAIAQLATLGATRDACLFALGGGVIGDLAGFTAACWMRGIDYVQVPTTLLAMVDSSVGGKTAVDIPQGKNMVGAFHPPRAVIADTDTLATLPLRELRAGLSEVIKYGAIRDPVFFHWLQTTREALLARDPAALAQAIARSCEHKADIVGRDPLEKGERVLLNLGHTFGHAIETTQGYSTPGSNNLNHGEAVAVGMVLAARLSNTLGLAPAEDTETLKNLLDAYGLPTVLPSGLTPEMLLERMRLDKKNIAGRLRLVLWRGIGHAEAVPDVDEAAVRQILAN
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYC_CANLF
Sequence: MDLLRRVETPAAAMPLNVSFANRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVASFSPRGDDDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPSPARGPGGCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKPCASPDSAAFSPSSDSLLSSAESSPRASPEPLALHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQPPAKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRARLDSGRVLKQISNNRKCASPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLLSEKDLLRKRREQLKHKLEQLRNSGA
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: RNH3_STRP6
Sequence: MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y120_FRAP2
Sequence: MNFDMSKLMQQAQKMQEQMKKAQQERENMEVIGESGAGLVSVTMTGKYDVKKVTIDDSLMSEDKEMLEDLIAAAVNSAVKKVEDSSSSADIGKMAKEAGIDLPNGFNFPFK
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Fphi_0115.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PLPP2_MOUSE
Sequence: MERRWVFVLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTITHGLMAGVIITATVILVSLGEAYLVYTDRLYSRSNFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDPDWSQVNCSGYVQLEVCRGSPANVTEARLSFYSGHSSFGMYCMLFLALYVQARLCWKWARLLRPTVQFFLVAFAIYVGYTRVSDHKHHWSDVLVGLLQGALVACLTVRYVSDFFKSRPPQPCQEDEVPERKPSLSLTLTLGDRP
What is the function of this protein?
Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P.  Has no apparent extracellular phosphatase activity and therefore most probably acts intracellularly.  Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound.  Through dephosphorylation of these bioactive lipid mediators produces new bioactive compounds and may regulate signal transduction in different cellular processes (By similarity).  Indirectly regulates, for instance, cell cycle G1/S phase transition through its phospholipid phosphatase activity (By similarity).
What are the official names of this protein?
Phospholipid phosphatase 2, Lipid phosphate phosphohydrolase 2, PAP2-gamma, PAP2-G, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c, PAP-2c, PAP2c.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y1227_ARCFU
Sequence: MIKSYLLKTGEELREHGDVPAEYRELFSILIENEFKNAVLILNGEALYFESNSVSGLVEVDRKHIGAAKILLRRVAKEAKKVDLSSIEEAFEFAEQLEKADLDGIAKFLR
What are the official names of this protein?
Uncharacterized protein AF_1227.
Protein: COX3_TRAOR
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTFGLIMWFHFNSTALLMLGLTTNMLTMYQWWRDIIRESTFQGHHTPVVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGHRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RSMD_HAEIN
Sequence: MKKIQTPNAKGEVRIIAGLWRGRKLPVLNSEGLRPTGDRVKETLFNWLMPYIHQSECLDGFAGSGSLGFEALSRQAKKVTFLELDKTVANQLKKNLQTLKCSSEQAEVINQSSLDFLKQPQNQPHFDVVFLDPPFHFNLAEQAISLLCENNWLKPNALIYVETEKDKPLITPENWTLLKEKTTGIVSYRLYQN
What is the function of this protein?
Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase D, 16S rRNA m2G966 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmD family.
Protein: CMOB_PHOPR
Sequence: MFSFSEFYKLIAQHETLRPWLNTLPKQLSDWEEAEHGDMGRWIRALKKFPTDKPDIIDIKNEVSVRYEDGIANGEQKRLESLLRLLHPWRKGPYNMHGIHIDTEWRSDWKWDRVLPHISPLQGRSVLDVGCGNGYHMWRMLGEGAALTVGIDPSNLFLIQFEAIRRLMGDDNRAFLLPLGIEQLPELKAFDTVFSMGVLYHRRSPLDHIIQLKNQLRKDGEVILETLVIEGDENAVLVPTGRYAQMHNVYFFPSAKALKVWMEKCGFVDVRIVDESVTTTDEQRSTDWMTNNSLPEYLSPDDPTKTIEGYPAPKRAILVARNPD
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: MURD_STRP3
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTQATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPYK_HYPJE
Sequence: MSQISRTQSIMATTAQEHLETGGRINWLASLNTAFTPARNFRRTSIICTIGPKTNSVEALNKLRDAGLNVARMNFSHGSYEYHQSVIDNVRASVAAHPGRPVAIALDTKGPEIRTGNTAGDVDIPISAGTVMNFTTDEKYATACDTQNMYVDYKNITKVIQPGRVIYVDDGVLAFDVLSIKDDQTVEVRARNNGFISSRKGVNLPNTDVDLPALSEKDKADLRFGVKNNVDMVFASFIRRAQDIKDIRDVLGPEGKQIQIIAKIENRQGLNNFAEILEETDGVMVARGDLGIEIPAAEVFAAQKKMIAMCNIAGKPVICATQMLESMIKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGNYPAESIHEMHEASLKAENTIPYVSHFEEMCTLVKRPVSTVESCAMAAVRASLDLGAGGIIVLSTSGDSARLLSKYRPVCPIFMVTRNPTTSRFSHLYRGVYPFLYPEQKPDFDTVNWQEDVDKRIKWAVTRAIELKTLTAGDTVVVVQGWKGGMGNTNTLRIVRADPDHLGIGQME
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: RL11_NEIMF
Sequence: MAKKIIGYIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAATQGMEPGLPIPVVITAFADKSFTFVMKTPPASILLKKAAGLQKGSSNPLTNKVGKLTRAQLEEIAKTKEPDLTAADLDAAVRTIAGSARSMGLDVEGVV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: M2DH_EMENI
Sequence: MPPLKLNSKNLAAILNAGKGQIKVPTYPRNGAVKEGIVHIGVGGFHRAHLAVYIDRLMQNHGVTDYAIAGVGLTPFDKKMRDILRSQDHLYTVIERSAKGSFANVVGSINSFLFAPDDREAVVAKMAHPDTHIVSLTITESGYYYNENTHELVSEHPDIQFDLDPANEKTPRTTFGFLYAALARRFKQGLNPFTVMSCDNMQKNGAITRHMLESFARLRNPEIAEWISKKGHFPNAMVDRITPQTAPADITALANDFGIQDDWPVVTEPFMDWVIEDHFCDGRPPFEKVGVKVVKDLRAVEEYEKHKLRLLNGSHSAIGYAGQLAGFQYVHEVLQNDTYKKFLWQMMQEEVKPLLPEIPGVDIDEYCRTLIERFSNPTIKDQLPRICLNASGKIPQFIMPSIAEAIWVTGPFRRLCFVAAAWFRYLHGVDDAGNKFDIEDPMLEELQAKAKAGGLEPHEILSIKSLFGDDLRGDKRFLQEITTAMQLIDRDGVLKTMPKYVD
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol 2-dehydrogenase, M2DH, MDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: SSRP_STRGC
Sequence: MAKGEGKVVAQNKKARHDYTIVDTIEAGMVLTGTEIKSVRAARINLKDGFAQIKNGEAWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTGMTLVPLKVYLKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARQMKNFNTR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y356_SIRV1
Sequence: MQKTIFYVYPQHHDVSFKFVAQEHVKMLREKYIVYEIPTLSFYQFTPFRYPISIIHPLFYSMWKWGKIEFSFFEQYRTRVSALLGVEVADTDKIAKQYIEYANNFTDGMILNSEWSVNAFKNSGLKVPAYKVFHNFKDRLLAKNEELKLDDQILYIEKLKKEKNFKLIFISLWHSDYRKGADIFHVIAKELQKERNDIYFLVKSGLPRTDFQDLKMFNIFGNTSFDNIVKMYRISDLYLLTSRGGSFELNGLEAFISKIPALATKGGAWEDYYPPNLKDLLIDSCENPQIFPDNPIHIGNGVQMCIGKAIDKILEVLDNYDNYKAKIEENYNFWIENFSYNAVKKQLLEVMEKYSN
What are the official names of this protein?
Uncharacterized protein 356.
Protein: DPH6_RAT
Sequence: MRVAALISGGKDSCYNMMRCIAEGHQIVALANLRPDDNQVESDELDSYMYQTVGHHAIDLYAEAMALPLYRRTIRGRSLETGRVYTRCEGDEVEDLYELLKLVKEKEEIEGVSVGAILSDYQRVRVENVCKRLNLQPLAYLWQRNQEDLLREMIASNIEAIIIKVAALGLDPDKHLGKTLGEMEPYLLELSKKYGVHVCGEGGEYETFTLDCPLFKKKIVVDTSEAVIHSADAFAPVAYLRLSGLHLEEKVSSVPGDDETTSYIHNS
What is the function of this protein?
Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.  Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor eEF-2 (EEF2) to diphthamide (By similarity).
What are the official names of this protein?
Diphthine--ammonia ligase, ATP-binding domain-containing protein 4, Diphthamide synthase, Diphthamide synthetase, Protein DPH6 homolog.
What is the protein family that this protein belongs to?
Belongs to the Diphthine--ammonia ligase family.