PharMolix/UniProtQA huggingface dataset:
Protein: OST4_CANLF
Sequence: MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNPKKQE
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.  Specifically involved in maintaining stability of STT3A-containing OST complexes.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the OST4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: RLMH_CLOP1
Sequence: MNITVISVGKLKEKYLKQAIDEYSKRLSRYCKLEIIELPDEKTPDNASEKEELQIKEKEGKLILSKIKDNMHVIAMDLKGNEITSEKFSKYIENCGVMGNSNITFVIGGSLGLSQEVIKRADYKLCFSKMTFPHQLFRVMLLEQVYRAFRIMKNEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_BRUO2
Sequence: MRCPYCQSEDTQVKDSRPAEDGAVIRRRRVCSVCGGRFTTFERVQLRDLMVVKKSGRRVPFDRDKLTRSIEVALRKRDVDSERVERAISGIVRQLESAGEAEVTSDEIGRLAMDALKGIDDIAYIRFASVYRNFSKAVDFHNVIDELTVSETGDNLET
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ENSA_MOUSE
Sequence: MSQKQEEENPAEETGEEKQDTQEKEGILPEKAEEAKLKAKYPSLGQKPGGSDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAGADKNLVTGDHIPTPQDLPQRKSSLVTSKLAGGQVE
What is the function of this protein?
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.  When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase.  Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents (By similarity).
What are the official names of this protein?
Alpha-endosulfine, ARPP-19e.
What is the protein family that this protein belongs to?
Belongs to the endosulfine family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_STRP8
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y1906_YERPA
Sequence: MIVYLHGFDSNSPGNHEKVLQLQFIDPDVRFISYSTLHPRHDMQYLLKEVDKAIQQGGDEKSLICGVGLGGFWAERIGFLCGIRQVAFNPNLYPQENMSGKIDRPEEYIDIASKCIDGFREKNRDRCLVVLSRHDEMLDSQRTAGDLHPYYEIVWDDKQNHKFKDLSPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YPA_1906.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: ETFR1_SALSA
Sequence: MANPLRSEVRQLYKNLLFLGREYPKGADYFGERLKRAFMKNKDVTDPKEIKKLVDRGEFVIKELEALYYLRKYRAMKKRYYEEELSTMLNIG
What is the function of this protein?
Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of etfa and etfb).
What are the official names of this protein?
Electron transfer flavoprotein regulatory factor 1, LYR motif-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MURQ_LISMC
Sequence: MLENLATEERNEKTIDLDTLSPKEILAVMNEEDLTVPIAIKKVLPQIELIVSGVISCFQKGGRLIYLGAGTSGRLGVLDAAECVPTFGVSKEQVIGLIAGGEKAFVAAIEGAEDSKILGENDLKQIKLTANDFVIGIAASGRTPYVIGALDYAKSVGAKTGAISCNANAKISAHADIAVEVVTGAEILTGSTRLKAGTAQKLVLNMISTASMVGIGKVYKNLMVDVLPTNKKLEERSKRIIMEATEADYETANKFYEAAEKHVKVAIVMILTNSTKEIALEKLSEAKGFVRNTIQK
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: CCG3_RAT
Sequence: MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGLCVAASEFHRSRHSVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRARSHSELLKKSTFARLPPYRYRFRRRSSSRSTEPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKLTMGTLLNSDRDHAFLQFHNSTPKEFKESLHNNPANRRTTPV
What is the function of this protein?
Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization.  Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.  Thought to stabilize the calcium channel in an inactivated (closed) state.
What are the official names of this protein?
Voltage-dependent calcium channel gamma-3 subunit, Neuronal voltage-gated calcium channel gamma-3 subunit, Transmembrane AMPAR regulatory protein gamma-3, TARP gamma-3.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Displays a somatodendritic localization and is excluded from axons in neurons.
Protein: OBG_STREM
Sequence: MFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFKVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAETGKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKILADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGLIEGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLMERPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPMIFPISSLAHQGLDSLLEATAELLAKTDDFLLYDEADFAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTNLERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_XANOR
Sequence: MSTNDNWYIEHFQPTGSAIGFRISGKLDEVQSLFQKIEIYQTTDWGKLMLIDGAVMLTSRDNFFYHEMISHPALFTHPTPKRVVIIGGGDCGTLREVLKHPGVESATQCDIDEQVTRMSEKYFPELCDSNHDARAELLFDDGVAYMANCPAGSVDIVIVDSTDPVGPAEGLFNKAFYESCFKALKDDGLLVQQSESPLALLDLIKEMRTEMGKAGFQSFKTLPFPQPCYPTGWWSVTMASKQAKADFAFRQGAAQAKGFETLYYTAHLHTGVLVAPPFVAKALGE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF76_SACHY
Sequence: MKKILFSMFYSILVGEEPDSVFLKKEGKQNQVKMIWIAPSSCAKDLTISEGTGATFLFNFHSRVSICFHALFLRPRNMKWTNSFS
What are the official names of this protein?
Uncharacterized protein ycf76.
What is the protein family that this protein belongs to?
Belongs to the ycf76 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYK_VIBCH
Sequence: MTDAVQNEINQEQIAQEENKLIAERRSKLDHIRKNCKANGHPNSFRRDSLAGDLQKKFGEKSKEELEALNHVVSIAGRVMAKRGPFLVIQETSGRIQAYASKEVQQELKDKYQGLDIGDIIGVQGALHKSGKGDLYVNMEQFQLLTKALRPLPEKFHGLTDQEMRYRQRYVDLIVNENSRNAFIVRSKVMSAIRNFMISKQFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGGFDRVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEELLSSVALEVLGSTSMPYGEHTVEFGGKYARMSMFDAIKHYNPNHAQIQALTEEDIQNRDLMVSIAKSVHVDVEPFWTCGQLLEEIFGETAEPKLMQPTFITGYPADISPLARRSDDNPFFTDRFEFFIGGREVANGFSELNDAEDQDARFKAQVEAKESGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVMLLTNTHTIRDVILFPAMRPQQ
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH2_CALS4
Sequence: MEVLEGLYYSKDHEWVKVEGDKVYIGITDYAQHSLGNIVYVELPEVGSELSAGDVLGVVESVKAASDVYTPVDIKVLEVNNSLVEDPSLINNDPYGSWMVIAELKDKSQLDKLMKADEYRKFLEEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein 2.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: ATPE_ARATH
Sequence: MTLNLCVLTPNRIVWDSEVKEIILSTNSGQIGVLANHAPIATAVDIGILKIRLANQWLTMALMGGFARIGNNEITILVNDAEKNSDIDPQEAQQTLEIAEANLRKAEGKRQTIEANLALRRARTRVEALNTI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: M148_CTEON
Sequence: ITFSKIYRSCKSNSVCGNQKCVRGRCV
What is the function of this protein?
Not toxic to mice by intracerebroventricular injection.
What are the official names of this protein?
U18-ctenitoxin-Co1b, U18-CNTX-Co1b, Venom peptide M14-8.
What is the protein family that this protein belongs to?
Belongs to the u18-CNTX family.
What are the subcellular locations of this protein?
Secreted.
Protein: MSRB_BURM1
Sequence: MSHDADDKTYPYRKDDAELRRRLTPLQYEVTQHAATERAFTGEYTDKEDDGIYKCVVCDTPLFESGAKFHSGCGWPSYFKPLNGEVIDEKIDYSHGMVRVEVRCNHCGAHLGHVFEDGPRDKTGLRYCINSAALNFESRPEND
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: CARB_XYLFA
Sequence: MPKRTDLRTILIIGAGPIVIGQACEFDYSGAQACKALRAEGFRVVLVNSNPATIMTDPDMADAVYIEPIHWRTVEKIIAKEKPDALLPTMGGQTALNCALDLADHGVLEKYGVELIGAKREAIRMAEDRELFRVAMQEIGLECPKAEVAKSLERALEIQAKVGFPTIIRPSFTLGGTGGGITYNRQEFEEIIKRGLELSPVHEVLVEESVLGWKEFEMEVVRDASDNCIIVCSIENLDPMGVHTGDSITVAPAQTLSDKEYQRLRDASIAVLRKIGVDTGGSNVQFGIDPQTGRVVVIEMNPRVSRSSALASKATGFPIAKIAAKLAVGYTLDELKNEITGGKMPASFEPSIDYVVTKIPRFAFEKFPQADARLTTQMKSVGEVMAMGRTFAESLQKAVRGLETGKVGLEPTGLDLSSEDDLVVLKRELKAPGAERLFYVADAFRAGFAVADVYALSYIDPWFLDQIEEIVAAEGRLVTDGLGSIDGARLRQLKRIGFSDARIAQLTGTNEVAVRALRRVLKVKPVYKRVDSCAGEFATGTAYLYSTYEEECEAAPSDRRKIMILGGGPNRIGQGIEFDYCCVHAALALREDGFETIMVNCNPETVSTDYDTSDRLYFEPLTLEDVLEIVEVEHPVGVIVQYGGQTPLKLAKALEANGVPVIGTSPESIDLAEDRERFQKLVQQLGLRQPPNCTARTAEEALVLAREIGYPLVVRPSYVLGGRAMEIVYGEADLARYVRDAVKVSNDSPVLLDRFLDNAVEVDVDIIADREGQVLIGGVMEHIEEAGVHSGDSSCSLPPYSLSAATQDDLRRQVIRLAQALNVIGLMNTQFAIQSNDDGSDIVYLLEVNPRASRTVPFVSKATGVPLAKIAARCMTGKTLVEQSVTCEVVPAYYAVKEAIFPFAKLQGVDPILGPEMRSTGEVMGVGRSFAAAFARAQEAGDIRAPQPGRAFVSVRDPDKKRVLPVVLALVERGFGVVATAGTYAWLQQNGVACEVVNKVAEGRPHVVDLIKNGEIVYIINTTEGRAAIADSFSIRREALQHCVTYSTTIAGAKALVNSLEFRGTGPVWSLQELHKELQV
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: MUTL_CROS8
Sequence: MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGAGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASISSVSRLTLTSRTADQQEAWQAYAEGRDMEVTIKPAAHPVGTTLEVLDLFYNTPARRKFMRTEKTEFTHIDEVVRRIALARFDVTINLSHNGKMMRQYRAVQGNAPRERRLGSICGPAFLEHALAIEWQHGDLALRGWVAEPKGTTAALAEIQYCYVNGRMMRDRLINHAIRQACEDKLGIDQQPAYVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVVSVLQQQAANPLSLNEPAEDAPRFQPENRVAAGKNQFADPAPRERVSARENDAPRYSSGGASAGSNAGRSAASNGGWPHATPGYQKQQGALYKQLLETPAVTPPPAAPSVTSAREVMPSAPALDGHSHSFGRVLTLVSENVALLERDGKLMLLALSVAERYLKQAQLLPHDEAPCAQPLLIPVRLKISGDERDIMTRAQPQLARLGIEIVLDGHHVTIRAVPLPLRQQNLQILIPELIGYLAQQPNADDAAIAGWLARHLVIAQPWSVAQAIATLAELERLCPQMVKTPPGGLLQPIDLQPAMNALTHE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MVP_PEMVM
Sequence: MASITFGNACTVVFGQVRKEEVTAGPVAVNLNEGTRMVVVPTAAQMATPTPSVSIKIINRWSNKAVSSYERQVEDVFANFFAKKERSDELLTRYYGKVVQKGNKLMVKRAPLHVARVLEKQRLQDIEDEKAFLQYRDAGVHVAGSVKFTDTRSRGQTVSFRTEHYKPTGKIVQKKKAQKQRANADVDHLIDEVMKICSADCKQVEFISMGKRRLTAKFKLFGKSVIPCIHLAHEQGRRLRRELDPRIHEQVIAHLVTGRKVRELIKDDMVTYGWSGAILNKNLFKRTPFRWDEVVIRGRLYGKLVDARSKLSECSKDKIHQYSSFEAQFWKGWKNKFDTLHPHNKDHICEPTINNEKCGEIVATIFQAIHPVIKVSCSTCRERLTKASNEELNEYLATNLACHKATFDDMRQQHATVNTVLNKIEQTSLANPNLKDSMEIVRLLQNLNQTQARQLMKVNNTLLKGNVATSEEFSDATTQLLEVTRWYAKHLSLVDEGSISSFRNKATSKSLINPSLLCDNQLDRNGNFVWGERGRHSKRFFENFFEEVVPGGGYKKYQIRNSPNCTRKLAIGNLIVPMSLERARNALIGESVERLPVTEACVSRVNGAFMHVASCVTSDNGSAHFSPLYSPTKRHLVVGTTGDSKYIDLPATESDKMYVAKEGYCYINIFLAMLVNVNEDSAKDFTKMIRDTIVPMLGTWPSMMDVATACYILTVFHPETKSAELPRILVDHTNKTMHVIDSFGSISTGYHILKAGTVSQLIHFASNELVSEMKHYVVGGEAPHARRMRMEKALIQGIFKPKQLVYLIEEDPYILMMSLVSPTLLINLFNVGGLEVAMKHWIKKEMNIGLIFSMLSSLAQKVSRADLVNEQITMIDANAAQFIETLAGIDVENPMRNELVSALTMMLARSDVDSTLNKTGFTGFSDTLLEMREKNYWRRAQQGMVRAKLVGKIFFNHFLEASAKAYYGTFAKHKATRYRRQVCNLMYLVTWKDQGPIQWSKKCNIRSV
What is the function of this protein?
Allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding (By similarity).
What are the official names of this protein?
P3N-PIPO polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae P3N-PIPO polyprotein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma.
Protein: PSCF_PSEAE
Sequence: MAQIFNPNPGNTLDTVANALKEQANAANKDVNDAIKALQGTDNADNPALLAELQHKINKWSVIYNINSTVTRALRDLMQGILQKI
What is the function of this protein?
Major component of the type III secretion needle structure that plays an essential role in translocation of effector toxins into host cells, facilitating the establishment and dissemination of infection.
What are the official names of this protein?
Type III needle protein PscF, Pseudomonas secretion protein F.
What is the protein family that this protein belongs to?
Belongs to the MxiH/PrgI/YscF family.
What are the subcellular locations of this protein?
Secreted. Cell surface. Note=Secreted via type III secretion system (TTSS).
Protein: UPK2_HUMAN
Sequence: MAPLLPIRTLPLILILLALLSPGAADFNISSLSGLLSPALTESLLVALPPCHLTGGNATLMVRRANDSKVVTSSFVVPPCRGRRELVSVVDSGAGFTVTRLSAYQVTNLVPGTKFYISYLVKKGTATESSREIPMSTLPRRNMESIGLGMARTGGMVVITVLLSVAMFLLVLGFIIALALGSRK
What is the function of this protein?
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells.  May play an important role in regulating the assembly of the AUM (By similarity).
What are the official names of this protein?
Uroplakin-2, UP2, Uroplakin II, UPII.
What is the protein family that this protein belongs to?
Belongs to the uroplakin-2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Heterodimer formation with UPK1A is a prerequisite to exit out of the endoplasmic reticulum (ER).
Protein: A8043_ARTBC
Sequence: MEILLIVLGAVVAGLLCPVQTAAEATITLTGSDIPTSISIHHGTRTPTSSGELSQSTFSSSSTNSSDSFYTTTSASYTLLVGSHTTSTVTANETTLSGNATATETSREPQPTNTRPCNGYAEFCARSYGNITQVAAHNSPFVRPGNIASNQELDVVTQLNDGIRMLQFQTHLVNGTIYLCHSSCDLLNAGTLESYLKKVADWLRDNPYDVVSLLIGNGDFVGVKNFTAPIQSSGLIDHVYTPKNHSIALDDWPTLSEVILSGKRAMVFMDYEANHGEVPYILDEFTYIWETPFSPTDRNFPCDIQRPPGLNEADARKRMYMANHNLNLEISIAGATILVPNTVLLNETNAVSGFGSMGAMAGNCTEKWNRPPNFLLVDYYNIGNVNGSVFQVAAKLNNVTYNGKCCGRTTSLASESVLGRLSGKLEMIYSMIVINILVMTIL
What are the official names of this protein?
Uncharacterized secreted protein ARB_08043.
Protein: GLGA_PROMM
Sequence: MRVLFAAAECAPMVKVGGMGDVVGSLPPALAKLDHDVRLIMPGYGKLWSLLDIPTDPIWRGQTMGNEFAIYETSHPSNGLPLYLVGHPVFDPERIYGGEDEDWRFTFFASATTEFAWNVWKPQVLHCHDWHTGMIPVWMHQDPEISTVFTIHNLKYQGPWRWKLDRMTWCPWYMQGDHTMAAALLYADRVNAVSPTYAREICTSEYGESLDGLLNYISGKLRGILNGIDLQDWDPGNDKSLPATFNADDLSGRAVNKQALQQRMGLEVNPDTYLLGMVSRLVDQKGVDLLLQVTERLLAYTDSQIVVLGTGERGLESGLWQLAIQNPGRFSVFLTYDDDLARLIYGGSDAFLMPSRFEPCGISQLLAMRYGSVPVVRKVGGLVDTVPSYDPIHQTGTGFCFDRFEPVDFYTALVRSWEAFRHRDCWRELQQRGMTQNYSWDRSALDYEQMYRDVCGFKEPSPDAAVVEQFSLGQGSDPSRQNQDSNAKKRTRRKKKGND
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RAD54_DROME
Sequence: MRRSLAPSQRGPLRPESRHSFTPPLLKKNKRSCQQELEREQELDRRRLGALRDASNTSELPLPIRFTANSEYELAIAKVLARKFKVPMDNYVPDYGGKRVLGVRRCISRRPLHDPMACNALVLFHPPAYTEHERMGMDPTKVLVHVVVDPLLSNILRPHQREGVRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGTPVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTLKKICSHPDLIYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIIDNNESAEKHFTRDDLKDLFTFDANILSDTHDKLKCKRCVQNIQMKPPPEDTDCTSHLSQWYHCSNNRGLPDNILAQAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEEKPESRKRSSTPASDDSADEDFRGF
What is the function of this protein?
Involved in mitotic DNA repair and meiotic recombination.  Functions in the recombinational DNA repair pathway.  Essential for interhomolog gene conversion (GC), but may have a less important role in intersister GC than spn-A/Rad51.  In the presence of DNA, spn-A/Rad51 enhances the ATPase activity of okr/Rad54.
What are the official names of this protein?
DNA repair and recombination protein RAD54-like, DmRAD54, Protein okra, RAD54 DNA repair protein.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3448_SHEDO
Sequence: MDIQQQTRGFRYFYISVWRFILHLKARLIDDQINIRAGHLAYVTLLSLVPMIAVTMSMLSAFPVFKGIRVNIESLVYSYFLPAAGDSAQVYINEFVNNASKGTFVGIIALLVVAILLISAIDKALNNIWRTTEKRSLVVSFSMYWMVLTLGPVLMGSSLVATSYVVSLELFSQSELSGLLPWLVERLPMLFSVASILLLYMVVPTQKVRFFHALLGAVVAALLFEAGKRAFAYYVTQFPSYEAIYGALATIPILFVWVYLSWMIVLVGAEITAALPEYLDDPFEKDGTKATTALTENKEVDESEPNQGNDTIA
What are the official names of this protein?
UPF0761 membrane protein Sden_3448.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBP_SACS2
Sequence: MSNSAVSYKPIVNIENIVATVTLEQSLDLYAMERSIPNIEYDPDQFPGLIFRLEQPKVTALIFKSGKMVVTGAKSTEELIKAVKRIIKTLKKYGIKIVGKPKIQIQNIVASANLHVNVNLDKAAFLLENNMYEPEQFPGLIFRMDDPRVVLLIFSSGKMVITGAKREDEVSKAVKRIFDKLAELDCVKPIEEEEELEL
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: DGGGP_METS5
Sequence: MNPFLKLVRIHNVIGAGLGAFTGYVASSMWKIDPTELILAVLVVALVDAGGNAINDVYDVEIDRINKPDRPIPSGAVSLRTATSLSYGLMGVGVILSALQGYLQFLVALLTSVALIFYARDLKRTGIYGNLVVATATALSLFYGGLSYHEGDWLQRIWIPVLYTFLLTLSREIVKGIEDYRGDLANHVNTLATTRGIASAWRVARVALIITEVTSPLPLFLGYNILYGIVLVPFLYITTKAVLAETSEEGASKARSLLKGSAFLGMVAFALGSLPFQFLFHYLP
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP).  This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Digeranylgeranylglyceryl phosphate synthase, DGGGP synthase, DGGGPS, (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase, Geranylgeranylglycerol-phosphate geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL36_MACCJ
Sequence: MKVRPSVKPICEKCKVIRRKGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.