PharMolix/UniProtQA huggingface dataset:
Protein: AX7A_TERSU
Sequence: MSALKFVLICGLVLLLIETIPGVSLNLMRATNRHQCDTNDDCEEDECCVLVGGNVNNPGVQTRICLACSRK
What is the function of this protein?
Elicits an uncoordinated twisting syndrome when injected into C. elegans, but has no effect on mice.
What are the official names of this protein?
Augerpeptide-s7a, Agx-s7a.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOB_HELHP
Sequence: MQESLNSNDFKEYAAKKAKHITSAKNIAPLLECIASLPTIPSHFYSDNGIHIVAQDKTLAQKYHKAIYTLATQLKPWRKGPFFLFDIHIDSEWQSFMKWQLLAPHCNLEGKYIADVGCNNGYYMFEMLLQGKKLYKKIIGFDPSGIFKCQFDFINHFINAPIEFELLGVEDLLAYSQAHNQSFDVIFCLGVLYHRFDPINTLKILSQSLNKGGELILDTLIYESNEEICLCPAQSYAKMSNVYFIPSIPTLKGWCERANLYDFEVINLTPTTTQEQRQSAWVDSQSLSAFLNETQTRTIEGYQAPLRGYFKLKKR
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: HEMA_INBNA
Sequence: DRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPKCLNCTDLDVALGRPKCMGTIPSAKASILHEVKPVTSGCFPIMHDRTKIRQLPNLLRGYEHIRLSTHNVINAETAPGGPYKVGTSGSCPNVTNGNGFFATMAWAVPKNDNNKTATNPLTVEVPYICTEGEDQITVWGFHSDNEIQMVKLYGDSKPQKFTSSANGVTTHYVSQIGGFPNQAEDGGLPQSGRIVVDYMVQKSGKTGTITYQRGILLPQKVWCASGRSKVIKGSLPLIGQADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RHLB_ALIFM
Sequence: MKKTHITEQNFADLGLQPQVIDGLNAKGFIKCTPIQAKALPVLLAGQDIAGQAQTGTGKTLAFLTATFNHLLTTPAPEGRKITQPRAIIMAPTRELAIQIFNDAESLIASTGLKAALAYGGERYEKQQQVIEQGVDILIGTTGRIIDFYKQGHIDFKMIQAVVLDEADRMFDLGFIKDIRFIFRRMPAPTERLNMLFSATLSYRVQELAFEHMQEPEHVVVEPEQKTGHRIKEELFYPSNDHKMALLQTLIEEEWPDRAIIFANTKHKCESVWGHLAADKHRVGLLTGDVPQKKRERILEEFTQGNVDILVATDVAARGLHIPQVTHVFNFDLPNEAEDYVHRIGRTGRAGASGNSISFACEEYAINLPAIEEYIEHSIPQSDYDASALLEDLPAPLRLQRRPQQNRRNNNGQRQGGNRKHSRPRQPRNTQS
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITA7_RAT
Sequence: MARIPRCDFLGLPGICYLLSFLLAGLLLPRASAFNLDVMGAIRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDRGANVQKESKENQWLGVSVRSQGAGGKVVTCAHRYESRQRVDQVLETRDVIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAATFSPDSHYLIFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLTGPAGDLTLNSYLGFSIDSGKGLMRSEELSFVAGAPRANHKGAVVILRKDSASRLIPEVVLSGERLTSGFGYSLAVTDLNSDGWADLIVGAPYFFERQEELGGAVYVYMNQGGHWADISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVTKPSQVLEGEAVGIKSFGYSLSGGLDVDGNHYPDLLVGSLADTAALFRARPVLHVSQEIFIDPRAIDLEQPNCADGRLVCVHVKVCFSYVAVPSSYSPIVVLDYVLDGDTDRRLRGQAPRVTFPGRGPDDLKHQSSGTVSLKHQHDRVCGDTVFQLQENVKDKLRAIVVTLSYGLQTPRLRRQAPDQGLPLVAPILNAHQPSTQRTEIHFLKQGCGDDKICQSNLQLAQAQFCSRISDTEFQALPMDLDGTALFALSGQPFIGLELTVTNLPSDPARPQADGDDAHEAQLLATLPASLRYSGVRTLDSVEKPLCLSNENASHVECELGNPMKRGTQVTFYLILSTSGITIETTELKVELLLATISEQDLHPVSVRAHVFIELPLSISGVATPQQLFFSGKVKGESAMRSERDVGSKVKYEVTVSNQGQSLNTLGSAFLNIMWPHEIANGKWLLYPMRVELEGGQGPEKKGICSPRPNILHLDVDSRDRRRRELGQPEPQEPPEKVEPSTSWWPVSSAEKRNVTLDCAQGTAKCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYMSVKSLEVIVRANITVKSSIKNLLLRDASTVIPVMVYLDPVAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKLGFFKRAKHPEATVPQYHAVKILREDRQQFKEEKTGTIQRSNWGNSQWEGSDAHPILAADWHPELGPDGHPVSVTA
What is the function of this protein?
Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers.  During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation.  Involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity.  Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells (By similarity).  Acts as Schwann cell receptor for laminin-2.  Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation.
What are the official names of this protein?
Integrin alpha-7, H36-alpha7.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: BIOB_STAAM
Sequence: MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: FMT_TRIL1
Sequence: MTGWRIIFMGTPEFACPTLQTLLDRTENVVAVFTQPDRPKGRGQKLQPPPVKELALRHGIPVHQPPKVRTPEVIEQIRALQPDLIVVIAFGQILPKALLEIPPQGCVNVHASLLPRYRGAAPLNWCIVNGETETGVTTMLMDVGLDTGPMLLKKTTPIAPDEDIQSLHDRMSQLGAELLGETLDGLKTGRIVPEAQDDSQSCYAPLLKKEHGLIDWQKPAVTIHNQIRGLSAWPGAVTSLGGAPLKLYRSSIGQGAGTPGTIIATGKNGIEVACGHGSLIIHELQAAGSKKMDAASFLAGHPLALGTLLMPHEVTA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: HPRK_STRP4
Sequence: MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGKLSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: YCGR_THISH
Sequence: MNETPAVPPSPEVEGSLNEQISHRRRILAVLDAMKDGRALLSARIENQRGYFNTTLLKIDAEKGYVFLDELAPADGHEKIAVGQTLHLYGFYNNLPAHFAIEVIHVGEHEGIAFYAGPLPKLIHYQQKRAHFRAYVGLGKELKVRLRKGDGAQISGRLQDISLGGFGALMPADSVFEDLEIVEVEALELPDHHAIACSAEIRHSHPTQGRVHIGARFTQLAPQAERQLLQAIVELEREQLRKQSRD
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  Binds 1 c-di-GMP dimer per subunit.  Increasing levels of c-di-GMP lead to decreased motility.
What are the official names of this protein?
Flagellar brake protein YcgR, Cyclic di-GMP binding protein YcgR.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: DAPE_XANOP
Sequence: MNDVLDLTCDLIARASVTPEDAGCQALLAGRLTAAGFACEHLRLGEVDNLWATHGSGAPVLVLLGHTDVVPPGPREAWTSDPFDPQIRDGVLYGRGVADMKGSVAAFVVAAEQFVAAHRAHAGTLAVLLTSDEEGDAIDGVRRVANLFRERGQAIDWCITGEPSSTERLGDLLRVGRRGSLSGTLTVKGVQGHVAYPHKARNPIHLAAPALAELVARQWDDGFESFPPTSLQVSNIHAGTGANNVIPGELQVAFNLRYTPHWDAPRLETEITALLDRHALDYALRWHRSGEPFYTPEGRLRSVAREVLGAFAGAPPEESTGGGTSDARFIAPLGAQCIEVGPVNASIHQVDEHVRVADLQALPALYRTLIERLLVE
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: YBAQ_ECOLI
Sequence: MKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSALINNNRKLTTEMAFRLAKVFDTTVDFWLNLQAAVDLWEVENNMRTQEELGRIETVAEYLARREERAKKVA
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YbaQ.
What is the protein family that this protein belongs to?
Belongs to the VapA/VapI family.
Protein: G6PI_PROMS
Sequence: MNGDLNSWDKFCNYLWFDKKLNIWLDISKINFTSKEIKNLEDKFKDVFSSIKELENGAISNIDENRQVGHYWLRNPSISPSSKIGEEIRADINSISEFGKQILNGDIKNKNNQQYTDVLWIGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEKLEELSEKLSTTLFVVVSKSGGTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKGSKLFKKATSENWLKIFNLQDWVGGRTSITSSVGLLPLALINENISEFIRGASLMDETTRIRDFKNNPAALLSSAWYLTGDGIGKRDMVVLPYRDRLQVFSKYLQQLVMESLGKKFNRNGQVVNQGISVFGNKGSTDQHAYVQQLRDGIDNFFCIFIELLDSPSTNIFDEKENPKEYLSGFLQGTRSALSSENRQSITITLEKLNCFSLGALIALFERAVSFYAELVNINAYDQPGVEAGKKAAANIIEYQQKVSHLLDEGGEYSINDITSLFDNSVSEPIFFILREMCFGNDNYLVKGDWSNPNSLVIQKINS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_ANAMM
Sequence: MLGAVGPGALWGFEREIMNLVPMVVEQTSRGERAYDIYSRLLKERIIFITGTVEDNMASLIVAQLVFLEAENPEKDISLYINSPGGVVTAGLSIYDTMQYIKPKVSTLCLGQAASMGALLLAGGEPGMRYALPNSRIMVHQPSGGFRGQATDIEIHAREILEIKRRLNEIYVKHTGKSLEEIESSMERDNFMVAEKAKDFGIVDKVIDKRGGEQI
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWI2_SCHPO
Sequence: MNVNKKQESIPVNTGSESISSNDNERFEQGKGVGSNLGSHFFEPVEYYYSDGKPMNQTEASQMKGTFSRDFSLNEMNNEFITDSFFCTTTPDPKTESPSFVKYNAHCDDHPEISGHVSSNDKDFAYFEDKSENQPLVTLPNENNQVIEPLSSQSCKSQLSTQNYSESDFGWNQLCDLDPIFKSLAFTDDTNLFPAFADSEAALIMLKKREMTRVKHRAGRPRKYSYVNKDLNFEEGLPRRRGRPTGWRKYPEKEEIYPTLSPRIKKPRKVFDAVVIPVTIKPSIYTEPSLPHHIDWNNGCSEEFDFEPSREDEDFPDLTSDSTGQDPLSSEPTIFDISPLPSDMEPTFSENSLITINKMAIEERKQSRRLEQPLAESQHQEDLLNPYGVDQDFDETCINESEQQATHIPNSSIKFNYDYTPPKSATSHKHKRVDLLASRKENVWTGLYGKVQTEMVSNRGEAVLNENNSKNRTNVTKPNSYKNSVLSIGNNHSNHSNIIKPNTYKNTILSNENNTPNYSNVCLSTSLINRSLPSLKSTMHPGVNKDLITRPFKNVNKMSVRKALIKPFHPPISKISRTRLTVSSPERLYCAKPISMATAPSETDSKLINRIRNLELEIGGLKEQLSVVELALDTDKNSKQIQVVERKIQNWRKSAQLAVEVLFPVFSLKFTTMLQEVPQSVLRTSANDLRTKPCSIGTYLEQLQIPFHLLQYNSETESWDLE
What is the function of this protein?
Required for normal mating-type switching.
What are the official names of this protein?
Mating-type switching protein swi2.
Protein: NOL12_PONAB
Sequence: MGRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTATTISDLDLSGARLLGLTPPEGGAGDESEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRQAQDSKKPPRATRTSKAQRRRLTGKAQHSRE
What is the function of this protein?
May bind to 28S rRNA.
What are the official names of this protein?
Nucleolar protein 12.
What is the protein family that this protein belongs to?
Belongs to the RRP17 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YHFL_ECO57
Sequence: MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISISKIIGGCGPTAQ
What are the official names of this protein?
Uncharacterized protein YhfL.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PETL_CYAPA
Sequence: MVEYLVILSGMFGLALACFFGLRSIKLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Single-pass membrane protein.
Protein: LIPB_SHEB5
Sequence: MQDTTLHIRHLGKQDYESVWHAMQHYTDTRDSESHDELWIVEHPPVFTQGQAGKSEHILNAGDIPVIQVDRGGQVTYHGPGQLVVYPLLDIKRSKVGVRQLVTHIEQSIVDMLAKYDINAYAKADAPGVYVDERKIASLGLRIRKGCSFHGLALNVDMDLAPFRRINPCGYAGLEMVQCKALGGPQTVIEAGEQLTITFSQLLGYQHLVHHQGLAAS
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C1QA_MOUSE
Sequence: METSQGWLVACVLTMTLVWTVAEDVCRAPNGKDGAPGNPGRPGRPGLKGERGEPGAAGIRTGIRGFKGDPGESGPPGKPGNVGLPGPSGPLGDSGPQGLKGVKGNPGNIRDQPRPAFSAIRQNPMTLGNVVIFDKVLTNQESPYQNHTGRFICAVPGFYYFNFQVISKWDLCLFIKSSSGGQPRDSLSFSNTNNKGLFQVLAGGTVLQLRRGDEVWIEKDPAKGRIYQGTEADSIFSGFLIFPSA
What is the function of this protein?
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.  The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
What are the official names of this protein?
Complement C1q subcomponent subunit A.
What are the subcellular locations of this protein?
Secreted.
Protein: RET4_PANTR
Sequence: MKWVWALLLLAALGSGRAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL
What is the function of this protein?
Retinol-binding protein that mediates retinol transport in blood plasma.  Delivers retinol from the liver stores to the peripheral tissues.  Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane.
What are the official names of this protein?
Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TCR3_ECOLX
Sequence: MKSNNALIVILGTVTLDAVGIGLVMPVLPGLLRDIVHSDSIASHYGVLLALYALMQFLCAPVLGALSDRFGRRPVLLASLLGATIDYAIMATTPVLWILYAGRIVAGITGATGAVAGAYIADITDGEDRARHFGLMSACFGVGMVAGPVAGGLLGAISLHAPFLAAAVLNGLNLLLGCFLMQESHKGERRPMPLRAFNPVSSFRWARGMTIVAALMTVFFIMQLVGQVPAALWVIFGEDRFRWSATMIGLSLAVFGILHALAQAFVTGPATKRFGEKQAIIAGMAADALGYVLLAFATRGWMAFPIMILLASGGIGMPALQAMLSRQVDDDHQGQLQGSLAALTSLTSITGPLIVTAIYAASASTWNGLAWIVGAALYLVCLPALRRGAWSRATST
What is the function of this protein?
Resistance to tetracycline by an active tetracycline efflux.  This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells.  This protein functions as a metal-tetracycline/H(+) antiporter.
What are the official names of this protein?
Tetracycline resistance protein, class C, TetA(C).
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G3P_STAAU
Sequence: MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFC_HAEIE
Sequence: MADVLSRFNSGKLWDFKGGIHPPEMKSQSNSQPLRHLPLGTDFYIPLKQHLGTTGNLLIKEGDYVLKGQALTKGDGLRMLPVHAPTSGTIKSIKPYVATHPSGLDEPTIHLQSDGLDQWIERNPIDDFSTLSPEQLIHKIYQAGIAGLGGAVFPTAAKIQSAEQKVKLLIINGAECEPYITCDDRLMRERADEIIKGIRILRYILHPEKVVIAIEDNKPEAISAIRNALQGANDISVRVIPTKYPSGATKQLIYLLTGIEVPSGERSSSIGVLMQNVGTMFAIKRAVINDEPLIERVVTLTGNKIAEKGNYWVRLGTPISQILSDAGYQFDKHFPIFAGGPMMGLELPNLNAPVTKLVNCLLAPDYLEYAEPEAEQACIRCSSCSDACPVNLMPQQLYWFARSEDHKKSEEYALKDCIECGICAYVCPSHIPLIQYFRQEKAKIWQIKEKQKKSDEAKIRFEAKQARMEREEQERKARSQRAAQARREELAQTKGEDPVKAALERLKAKKANETESTQIKTLTSEKGEVLPDNTDLMAQRKARRLARQQAASQVENQEQQTQPTDAKKAVVAAAIARAKAKKLAQANSTSEAISNSQTAENEVEKTKSAVEKTQENSTALDPKKAAVAAAIARAKAKKLAKTQTTLENNQE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rnf electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NTPPB_PARXL
Sequence: MSDSLNRPPRLILASSSPYRRELLQRLRVPFDVAVPAIDETPLAGETPEVTALRLAQAKARAVAGGLGAGVAALVIGSDQVATYDGLQIGKPGTHANALAQLQAMRGREVQFHSALCLFDSRSGTVQAVDVVTRVQFRDLPDAALEAYLLAETPYDVAGSAKSEGLGIALLEAIHSDDPTALVGLPLIALSRMLLAVGYPLLGAQ
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBR4_RAT
Sequence: MDKVCAVFGGSRGIGKAVAQLMAQKGYRLAIVARNLEVAKATASELGGIHLAFRCNIAKEGDVHSTFEEMEKHLGPVNFLVNAAGINRDSLLVRTKTEDMLSQLHTNLLGTMLTCRAAMRTMIQQGGSIVNVGSIIGLKGNVGQAAYSATKGGLIGFSRSLAKEVARKKIRVNVVAPGFIHTDMTKHLKEEHFKKNIPLGRFGEALEVAHAVVFLLESPYITGHVLIVDGGLQLTA
What is the function of this protein?
Component of the heterotetramer complex KAR (3-ketoacyl-[acyl carrier protein] reductase or 3-ketoacyl-[ACP] reductase) that forms part of the mitochondrial fatty acid synthase (mtFAS).  Beta-subunit of the KAR heterotetramer complex, responsible for the 3-ketoacyl-ACP reductase activity of the mtFAS, reduces 3-oxoacyl-[ACP] to (3R)-hydroxyacyl-[ACP] in a NADPH-dependent manner with no chain length preference, thereby participating in mitochondrial fatty acid biosynthesis.  The homotetramer has NADPH-dependent quinone reductase activity (in vitro), hence could play a role in protection against cytotoxicity of exogenous quinones.  As a heterotetramer, it can also reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase, 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit, KAR beta subunit, Carbonyl reductase family member 4, CBR4, Quinone reductase CBR4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.