PharMolix/UniProtQA huggingface dataset:
Protein: GLGB_SYNS3
Sequence: MTSAVLDWMVQDSRRLAECRHDHPFSLLGPQQLESGQWVVRAWVPEAETVELILDGERLSMQTPHHPWVFEAECSRDPGHHYKLQIRRGGIEHEQFDPWAFRHEWMGEMDRHLFAEGNHHHIWRRMGAHRCQQGGIQGVMFCLWAPNALTVSVIGNLNSWDGRYHPMQQRLGGIWELFVPELEEGHFYKYEIRTQDGHCYQKADPYGFQHEVRPDTSSIVSHLDGFQWNDDAWINSRDRRNPLDQPISVYEMHLGSWIHASADDPFIEADGTPRPPVPAADLKPGARLLTYPELADRLIPYVKEQGFSHIELMPITEHPFDGSWGYQVTGWYAPTSRYGTPDEFRAFVDRCHAEGIGVIIDWVPGHFPKDSHGLAFFDGCHLYEHADPRIGEHKEWGTLIFNYSRNEVRNFLVANLVFWFDQFHIDGIRVDAVASMLYRDYLRPDGEWLANEHGGRENTEAVRFLQQANHVLFEHFPGALSIAEESTTWPMVTQPTENGGLGFNLKWNMGWMHDMLDYFELDPWFRQFHQNNITFSIWYTYTENFMLALSHDEVVHGKSHLLHKMPGDDWQKYANTRALLAYMWTHPGKKTIFMGMEFGQRAEWNVWGDLQWDLLNYEPHAGVHRMVKELNALYKQEPALWQDDFDQYGFQWIDCNDNRHSVISFMRRESTSGSWLVVVANFTPQSHSHYKVGVPISGFYEEIFNTDAAKYGGSNLGNLGGKPSDEWGIHGYENSLDLCLPPLSLMVFKHDPKKSLAEVTNKERA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: LEUD2_THEMA
Sequence: MVVKIKGKVFVFGDNVNTDEIIPARYLNTSDPQELAKYCMEDARPGFGRRDDIKGSIIVAGENFGCGSSREHAPVAIKAAGISCVIAKSFARIFFRNAINIGLPIVELKEADEFEEGDIAEVDLENGVVRNLTKGKEYRIRPYPEFLMKIMEAGGWLEYCLKEVGE
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit 2, Alpha-IPM isomerase 2, IPMI 2, Isopropylmalate isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: NADD_LEPBL
Sequence: MTSPILTGIFGGSFDPPHEGHSGILKSFFREVPDCREIFLIPNRQNPLKGEKFSSSENILEMLNLFVSEFSETIRILDLELNHPGPSYTIETIQKLKTLHPNREFVLLIGEDNYSNFHKWRNYEKILDEVRKVFVFRRFSEVVPRNSKLFSQFQFLKNPLIPASSTDLRQSFFQSTIPDRIPKKVLDYILRNRLYSK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: HISZ_RHIE6
Sequence: MPLINLPEFSAELLSEFDARKAERIDTPVIQPAEPFLDIAGEDLRRRIFMTESETGASLCLRPEFTIPVCLRHIETATGTPKRYAYLGEVFRQRRDGANEFYQAGIEDLGDINIPSADARAIGDATGILARLLPGRRLSVTLGDQAVFEAVVQALGLPLGWQKRLIHAFGNMTQLEALLAGLVSPQFVTGLDDDIARLIAAGDEQALIAHIEQEMQATGYSTNASRSPPEIARRLKEKLVLSETRLDDAAFHVLEEFLSLHVPLVNASAALAGFADAAGLKLGNALSRFNGRVGALADAGVDLSCLDYRAAFGRPLDYYTGLVFEVTAEGSSAVLAGGGRFDRLLTFLGATDRIPAVGFSFWLDRIETERAAA
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_YERPG
Sequence: MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIGLSASLLLALLAERGLSQALLEQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAEALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLATAGIGTAIGVLLRAHQQGNLRQVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGDVANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHCQWAPEDAAVYNPAFDVTPAALISGWVLDSGVITPEQVAAGFFQPHR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: UVRA_RICCN
Sequence: MIMNQEYIKVRGAKEHNLKNINVNIPRNKFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSSYARQFLHLQNKPNVESISGLSPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLYARVGIPYSPATGLPIHSQTVSEMVDIINELPKGTKIYLLAPIVRGHKGEFKREIMDLKKQGFQKLIVNGEVCEIDDLPKLDKNKKHNIEVIVDRIVLDESLGNRLADSLESSLNLAEGITYLEIVELPPAVKSEFEKNQRITFSEQYSCPVSGFQLTEIEPRIFSFNSPFGACPKCEGIGKEFFFDRDLIVPDQRIAIKDGAIVPWGSTASKFILETLKALADHYKFSIEVPFVSLSQNVKDILFEGSGEEAIKFEFHDGSKTQIIKQPFAGIIPSLQEKDRTIESVLIKEELAKFKSEHKCTACSGFRLKDEALCVKIANLHIGEVAGMSIAALQKWFSHLEEKLNKKQLFIAERILKEITERLKFLMNVGLDYLTLSREAGTLSGGESQRIRLASQIGSGLSGVLYVLDEPSIGLHQRDNTRLIETLKRLRDLGNTVLVVEHDEETIYEADHIIDIGPGAGIHGGRVIAEGNVEEIKNFEESITGRYLSGRQTIKVPSETRVGHDNRAIELLGAVSNNLDNVDIKIPLGTFTAITGVSGSGKSSLMIHTLYKAALKHLEPTSKVFPGKYRELKGLEYIDKIIDINQSPIGRTPRSNPATYTGAFTHIRDWFVELPESKARGYKVGRFSFNVKGGRCEACQGDGLIKIEMHFLPDVYVKCDICNGHRYNRETLEIKYKGKSIADILMMTVEDAMQFFEKIPLIYEKLITLNEVGLGYIKIGQSATTLSGGEAQRVKLAKELSRRSTGKTLYILDEPTTGLHIDDINKLLKVLHKLVDMGNTVLVIEHNLDVIKTADYIIDVGPEGGDKGGKIVVCGTPADIAACEESHTGRYLKQYLV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOMPA_CHLPS
Sequence: MKKLLKSALLFAATGSALSLQALPVGNPAEPSLLIDGTMWEGASGDPCDPCATWCDAISIRAGYYGDYVFDRVLKVDVNKTFSGMAATPTQATGNASNTNQPEANGRPNIAYGRHMQDAEWFSNAAFLALNIWDRFDIFCTLGASNGYFKSSSAAFNLVGLIGFSATSSTSTELPMQLPNVGITQGVVEFYTDTSFSWSVGARGALWECGCATLGAEFQYAQSNPKIEVLNVTSSPAQFVIHKPRGYKGASSNFPLPITAGTTEATDTKSATIKYHEWQVGLALSYRLNMLVPYIGVNWSRATFDADTIRIAQPKLKSEILNITTWNPSLLGSTTTLPNNGGKDVLSDVLQIASIQINKMKSRKACGVAVGATLIDADKWSITGEARLINERAAHMNAQFRF
What is the function of this protein?
Permits diffusion of specific solutes through the outer membrane.
What are the official names of this protein?
Major outer membrane porin, MOMP.
What is the protein family that this protein belongs to?
Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: MURC_RHOPS
Sequence: MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASESANVNRLREKGIAISVGHKADNIAGADVLVVSTAIKRDNPELLAARAQRIPVVRRAEMLAELMRLKSCIAIAGTHGKTTTTSMVAALLDAGDVDPTVINGGIINAYGTNARLGAGDWMVVEADESDGTFLKLPADVAVVTNVDPEHLDHFKTFDAVQDAFRIFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGENPQADARLLDLKPSGAGSTFKVAFRDRKAGTAHEITDLMLPMPGPHNALNAVAAIAVAHELGLSDDTIRKALAAFGGVRRRFTKTGEWNGVTIIDDYGHHPVEIAAVLKAARQSTSAKVIAVVQPHRFTRLQSLFEEFCTCFNDADTVIVADVYPAGEAPIAGIDRDHFVLGLRAHGHREVIPLQDSASLAGVVAGVARSGDYVVCLGAGNITQWAYALPGELKALG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_GEOMG
Sequence: MKRTFQPSNTSRKRTHGFRVRMSTKNGRLVIKRRRARGRKRLAVTIAGK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: MLTF_VIBCH
Sequence: MTPFAYKLPIRALWLGLLSLLLVGCQIDSEPKSELEKIRERGVLRVGTLNNPLSYYIGPDGPTGLDYELAREFAKELGVKLEMKPAYRLSSLFPALKNGEVDIIAAGLSQSEERLKDFRAGPAYYYVSQQVVYKKGDWRPRSFKQLVERQQTLLKDNPELAFFSVVDDSHFEHTLLAKQQKYPDFQFHVDSNSDVNDLLKKVSQGELLFTMADSVEVSLSQRIYPELAAAFELTEDQPISWFIRRSDDESLYALMIEFFGNLKQSGYLASLEEKYIGHIGAFDYVDTRAFIRALDTRLPRWTPLFQKYSAEFDWRLVAALAYQESHWNPYAKSPTGVRGLMMLTLPTARSVGVSDRLDPEQSIRGGVEYLRRMMERVPDSISEHEKIWFALASYNIGYGHMMDARRLTKSQGADPDSWADVKDRLPQLQQKKYFTQTRYGYARGDEARNYVENIRRYYQSIIGHLEQRQLATGDESIEDLTVIALDEEFFNEEANREILDEEAEALESESLENSESSAEPSAKPSTESKN
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: KDSB_SYNC1
Sequence: MSITAVIPARYASSRFPGKPLARILGKTMIQRVYERTAQAACIDRVVVATDDSRIADVVSGFGGEVQMTRADHATGTDRLAEVTARIDTQLIVNVQGDEPLIDPHMIEAAVAPLSEDPAIPMGTLKTPLLNWQEYRDPNVVKVVTDRRGFALYFSRAPIPHPRELAVDDSAVSPASMGLFRHIGLYVYRKDFLLTFAGLPESPLERLEKLEQLRALENGYAIRVVETDRVSLGVDTPEDLVRVEAHLRGL
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGT1_LACTC
Sequence: MSASRRESEPKEAETSPEAGGAASDRRRSKTSRACDQCREKKTRCDFSDERPICSACQRMGKTCTFERVPMKRGPTKGYTRNSEPPEGFDTSRRGSRKRSSSDVFKGDAGRPRADPVSLPPLAQYLPQSGSQPRLQPLLAPGAQPQQQFWKVPYYEYQHQRRGSIDSLGSDVSNRNGSEQLAYLPSNASSGSQFYPASQAQYASQLPSDVEGANPEDCRGSLSLPAIQKFQQPPSGYYLQYPYSQFSMLPQQQQQQQQQNAQQSYFTSQYVPPAAPPGAEHFKEFDEGFHSRKGSDVSVAVSPSSPVQVTRTQQAGLNSESRDTNTATAVSPKPLPKPSKPQMQTERSSSKSDGNHNGPRKQKRKNSNRNKPGSQSSIESIASSSHASIIYGKIPDKQLIDIYFEFIHPNFPVIPINKETLTDDLLLVNTQPISPVHELNTYILHWFRNSLELLVRVALKKPSGSGQAYSDGAVDILDSQATFINALNECFQRIVDIHPGLRENEKLLSLKTKFIYLATFSILNYILAFVGYDNSFVLGMSVTIYNECKLYRYLMYDELPSNDTEASENEDEAGAGDAHASGTPERGKSAKHDLGHQVLFKRLYVLLVVFDSLQSCAFGVPKLISVPLAELTEETFKFSTGKWCVERDPQRFETIRQSLVLGQVLSWLSISRKSVRRNSLQAAPQDASWKDEKSDSVSSSLFAKFLVQKHEMMEDFLLLAPLENSSHLLTFDLLSKSSTAICGLISSMHRLLALLMKINPTNSVDPNNRPPLRQGDFVHTDTEIQSESSNPPAATAAPDSCDADKFDVYRKLLGLNGGQERHVAQGTISPFVISIVVEIRNVLELVKHLPTSIIGVVVNLLPNGEGENYQKRSHRLVMSLSNAMNELVQITSLISLLKPFKMFDHTLRSNRPSAKVSTKLLRQKFAPESVKTPSSQPPSSSPGPNSDGSNNTSLSQNTVMHAILDAAWDLMDGEELGWL
What is the function of this protein?
Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose.  In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator.  In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription (By similarity).
What are the official names of this protein?
Glucose transport transcription regulator RGT1, Restores glucose transport protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDS1/RGT1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RSGA_LEUMM
Sequence: MKTGRIIRSLSGYYDIQLPSGDIQRTRARGEFRKSKQKPLVGDFVDFESENDEGFIWAIHERENFLVRPPIANIDIAVIVTAAKEPDFAPNLLDRQLVALEAANVRPLIYFSKMDLLEKSEHEKINHVANYYQSIGYDVIFSDSKSAFEALKMMLKDHVSVFMGQTGAGKSTLLNHLSPQLGLETGEVSKALSRGKHTTRQVTLIEVDEALIADTPGFSSYEVFDFPVEELDDYFPEFVEKRQDCRFRGCLHLNEPGCAIKEAVAVGTITQSRYNSYKAFYELIKAQKPKYKTDN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EYA1_HUMAN
Sequence: MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGTEVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAYGQTQFTTGMQQATAYATYPQPGQPYGISSYGALWAGIKTEGGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL
What is the function of this protein?
Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (By similarity).  Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1.  'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19234442).  Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis (By similarity).  Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity).  Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity).  Together with SIX1, it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2 (By similarity).
What are the official names of this protein?
Eyes absent homolog 1.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. EYA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: DCXR_BOVIN
Sequence: MDLRLAGRRALVTGAGKGIGRSIVKALHAAGARVVAVSRTQADLDSLVRECPGVETVCVDLADWEATEQALGGVGPVDLLVNNAAVAFLQPFLEVTKEAYDMSFSVNLRAVIQVSQIVARGLIARGAPGVIVNVSSQASQRGLTNHSVYCSTKGALDTLTKVMAVELGPHKIRVNAVNPTVVMTPMGQAAWSDPQKAKAMLDRIPLGRFAEVENVVDTILFLLSDRSSMTTGSTVPVDGGFLAT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose.  Participates in the uronate cycle of glucose metabolism.  May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules (By similarity).
What are the official names of this protein?
L-xylulose reductase, XR, Dicarbonyl/L-xylulose reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Probably recruited to membranes via an interaction with phosphatidylinositol.
Protein: SPIC_BOVIN
Sequence: MACAEQDKLGQAFEDAFEVLRQHSTGDFQYSSDYKNYLAFINHRSHIRGNSNSYGVQPAEEPIYNWRTVINSATDLYFEGNIHQSLQNIPENQLVQPALLQQKGGKGRKKLRLFEYLHESLCNPEMASCIQWIDQTKGIFQFVSKNKEKLAQLWGKRKGNRKTMTYQKMARALRNYGRTGEIIKIRRKLTYQFSEAILQRLSAPYFLEKEIFYSQYVQPDQGYLSLNNWNANYNYTYANYHELSHPDC
What is the function of this protein?
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis.  Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer.  Regulates VCAM1 gene expression (By similarity).
What are the official names of this protein?
Transcription factor Spi-C.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLTOP_HUMAN
Sequence: MATNYSANQYEKAFSSKYLQNWSPTKPTKESISSHEGYTQIIANDRGHLLPSVPRSKANPWGSFMGTWQMPLKIPPARVTLTSRTTAGAASLTKWIQKNPDLLKASNGLCPEILGKPHDPDSQKKLRKKSITKTVQQARSPTIIPSSPAANLNSPDELQSSHPSAGHTPGPQRPAKS
What is the function of this protein?
Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells.  Regulates basal body docking and cilia formation in multiciliated lung cells.  Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.
What are the official names of this protein?
Protein Flattop, Cilia- and flagella-associated protein 126.
What is the protein family that this protein belongs to?
Belongs to the Flattop family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Apical cell membrane. Cytoplasm, cytoskeleton, cilium axoneme. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells (By similarity). Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme (By similarity).
Protein: DTD_THEAB
Sequence: MRAVIQRVKNAKVEVEGKTVGKIENGLLVLLGVGKDDNKEDIKYLAEKIINLRIFDDENGKMNLSLLDINGELLIVSQFTLYGDCRKGRRPSYSESAPPDIAKKLYEEFVNACKNYNLKVETGEFGAHMQVSLVNDGPVTLLLDSKKVF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_STAAB
Sequence: MPAVTYEHIKTCKQSGARLGIVHTPHGSFETPMFMPVGTKATVKTMSPEELRQIEAKIILGNTYHLWLQPGNDIIKHAGGLHKFMNWDGPILTDSGGFQVFSLSNLRKITEEGVEFRHHTNGSKLFLSPEKSMQIQNDLGSDIMMAFDECPPMPAEYDYVKKSIERTTRWAKRCLDAHQRPEDQALFGIIQGGEHEDLREQSAKDLVELDFPGYAIGGLSVGEPKPVMYKMVEHTEQFMPKDKPRYLMGVGSPDALIECSIRGMDMFDCVLPTRIARNGTCMTSQGRLVIKNAKFADDLRPLDENCDCYTCQNYSRAYIRHLIKAEETFGIRLTTIHNLHFLLKLMEDIRQAIREDRLLDFKEEFFEQYGLNVENPKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RODZ_PECAS
Sequence: MNTETTQDTTEAKLPGERLREARERLGLTQQTIAERLCLKITTVRDIEDGTTPADLAPTFLRGYIRSYAKLVHLPEDNLLPIMDKQAVPKAISVSPMQSFSLKKSRKKRDGWLMIITWLVVLVVLGLTGAWWWQNHQAQQAEINSMVDHASSMQSQTEGQSVPLMDNSAPQETSTAGSAATPPSTPVDLSATIAATPSTPPSSTTASSAAPSSQSPSQANATQSQAAGNALLGAGAVAPAATVADSNPVSAAHALVMTFTADCWLEVTDVSGKKLFSGMQRNGSTLNLDGQSPYQLKIGAPAAVQIKFQGKPVDLSRFVRSSQVARLTLTAE
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: SECA_CAMHC
Sequence: MIQKALGKIFGTKNDRIVKAYAKRVAKINALEPTYEKLSDDELKDKFSKLKEQVLAQKLTLDDALYDVFAIVREASKRVLKMRHFDVQLIGGMVLHDGNIAEMKTGEGKTLVATLPVVLNAMNKKGVHVVTVNDYLAKRDAADMGVLYNFLGFSVGVILGGNYDDKARKEAYNCDITYGTNNEFGFDYLRDNMKFRKEDKVQRGHNFVIVDEVDSILIDEARTPLIISGPTNRTLDGYIKANEVAKQMKCGEPADPLDKNSKATGDFTLDEKNRAVMITEAGISKAEKLFGVDNLYSLDNAVLSHYLDQALKANYLFEKDVHYVVKDGQVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVKIQEESQTLADITFQNYFRLYDKLSGMTGTAQTEATEFSQIYKLEVISIPTNLPVKRIDQNDLIYKTEKEKFDAVIAQIKYLHAKGQPVLVGTASIEKSEKLHELLTKEKINHSVLNAKNHEKEAQIIANAGDKGAVTIATNMAGRGVDIKINDEVRALGGLYILGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLEDNLLRIFGSDKIKHIMERLGLKEGESIESRLVTKAVENAQKKVESLHFESRKYILEYDDVANEQRKVIYRYRNELLEADFDLHDKIISNREDYIANVLDRLEIFDGDSKENFDIQKITSIIKSETTEILDENKLSKAEDYKELKEEIIKELRDFYEEKMAPVDNEQRKSIEKMLYLQIVDRDWREHLYQMDILKTGIGLRGYNHRDPLTEYKKESYNLFVELVMRLKSDSIRTLHSIRFKTQEEIEAERRAIAELQAKLQEEEQKKLKMSGADKGGEDLEETKNVPYRAPKKIGRNEPCPCGSGKKYKDCHGKSGPKKGLFANND
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CM32_CONLT
Sequence: MLKIGVVLFTFLVLFPLATLQLDADQPVERYAENKQDLNPNERMKMIMSALGQRRCCISPACHEECYCCQ
What are the official names of this protein?
Conotoxin Lt3.2, Lt3b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.