PharMolix/UniProtQA huggingface dataset:
Protein: AROB_PROM4
Sequence: MNQNSIRIKIKLAHNPYEVVIKKNGLARIGEELKKIGFKKATKVLVVTNKDVSVHYGKEFIHNLSDNGFNPTLIEIKAGEERKNLATISDIHNAAYTSRLERGSLMIALGGGVIGDMTGFAAATWLRGVSFVQVPTTLLAMVDASVGGKTGVNHPKGKNLIGAFHQPKLVLIDPITLKTLPEREFKAGMAEVIKYGVISDKKLFRKLEDAPRLDKLETLTDRFLLEIIQRSVQTKAHIVELDEREGGIRAVLNYGHTFGHAIEALCGYGTWLHGEAVSMGMIAIGQLALERNIWNISDLERQRKVLCQAGLPTIWPRVCAEDVIEILKSDKKVKDGEINFIVPTEIGKVEIIKNFTVNEIKQALQKLASK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM311_CONRE
Sequence: DQPVERHAENKRHLIPAVMRAMTMNADRRVQCCRIEFCDEDCGCCYH
What are the official names of this protein?
Conotoxin reg3.11, Rg3.11.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUC_STAAW
Sequence: MTEYLLSAGICMAIVSILLIGMAISNVSKGQYAKRFFFFATSCLVLTLVVVSSLSSSANASQTDNGVNRSGSEHPTVYSATSTKKLHKEPATLIKAIDGDTVKLMYKGQPMTFRLLLVDTPETKHPKKGVEKYGPEASAFTKKMVENAKKIEVEFDKGQRTDKYGRGLAYIYADGKMVNEALVRQGLAKVAYVYKPNNTHEQLLRKSEAQAKKEKLNIWSEDNADSGQ
What is the function of this protein?
Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
What are the official names of this protein?
Thermonuclease, TNase, Micrococcal nuclease, Staphylococcal nuclease.
What is the protein family that this protein belongs to?
Belongs to the thermonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: CSPLA_PHYPA
Sequence: MSTVAQDSAPGGGKIQDAMEQGAPGASSAAVVPEGGHYTQTPSPAFQAVKKNINHMSAFSLGLRVAEFVLSVIAFSLMASADQNGAVYSTFTSYSFVLAVNVLVVFYTIGQIIMSVLLLVSGSTPKKIYLFITFGCDQLSAFLLMAAGAAGASVALIINRGGVTDAYGNGCIDGKITSFCSHAQASVAFTFLSFFCMVISSLLGVYSLAPYLIL
What are the official names of this protein?
CASP-like protein UU5, PpCASPLUU5.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCDB_FRASN
Sequence: MLLSDRDIRAEITAGRVRLDPYDEGLIQPSSVDLRLDRAFRVFQNHRYSHIDPAVEQEDLTELVAPEGDEPFVLHPGEFVLGSTLEVVTLPEDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHVTLELSNVATLPIKLWPGMKIGQLCLFRLSTPAEHPYGSAIYGSRYQGQRGPTPSRAYRDFTRAAVPEIPNGSHGA
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ARGR_ECOLU
Sequence: MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y545_STRE4
Sequence: MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSVRHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES
What are the official names of this protein?
UPF0291 protein SEQ_0545.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_METFK
Sequence: MNKLRLFRSFFAFLLPFGMATGAAHGALTVEIVGGAAQQIPIAVVPFAQQGVIPGQQDTIANVIGADLRRSGLFRVLETRGVANQPSDISQVNYQDWAAIQAQALTIGNIETLPGNRLKVSFRLLDVYKQSQLVGMEYNITPSQLRLTAHKIADVIYQKLTGEQGVFATRIAYVSKSGGRYALQVADSDGYNPQTVVSSAEPIISPVWSPDGTKLAYVSFEKKKPIIYVQSLVSGQRTVLANFKGNNSAPAWSPDGKRLAIVLTHAANSQIYSINADGTGLQQLTRTTAIDTEPTWSPDGRYIYFTSDRGGSPQIYRMPSSGGEASRMTFEGSYVVSPRLSPDGKSLAYIRRDGGQFRVALQDLQTGQVQVLSDGPKDESPSFAPNGRMLLHATRVGGRGALAAVSADGRVKQRLSESGGDVREPAWGPIISQ
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y1246_THEAB
Sequence: MSGHNKWANIKHRKAAQDAKKSKIFTKLIREIIVAAKEGGGDPETNPRLRAVLERARAANMPKDTIEKSIKKGTGELEGVDYQEIIYEAYAPAGVALYIYAMTDNKNRTAQELRHLLSKHGGSLAESGSVAWLFERKGIIEIPKEKIADFEEFAMVAIDAGAEDIIEDDPIQVITAPDMLTEVKDKLAENGFEGEAKVTFIPKNTVKVTGADAEKVLKLVSVLEDNDDVQEVYANFEIDDKELEEIMSKLEG
What are the official names of this protein?
Probable transcriptional regulatory protein THA_1246.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_SALDC
Sequence: MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQEAVEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVEEAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPLKRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLPVDRLPSAAMTFTPHDGRGSRLEALAARWRTLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAZA2_PONAB
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: RISC_RAT
Sequence: MELSRRICLVRLWLLLLSFLLGFSAGSALNWREQEGKEVWDYVTVREDARMFWWLYYATNPCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDTRLKPRNTTWLQWASLLFVDNPVGTGFSYVNTTDAYAKDLDTVASDMMVLLKSFFDCHKEFQTVPFYIFSESYGGKMAAGISLELHKAIQQGTIKCNFSGVALGDSWISPVDSVLSWGPYLYSVSLLDNKGLAEVSDIAEQVLNAVNKGFYKEATQLWGKAEMIIEKNTDGVNFYNILTKSTPDTSMESSLEFFRSPLVRLCQRHVRHLQGDALSQLMNGPIKKKLKIIPDDVSWGAQSSSVFISMEEDFMKPVIDIVDTLLELGVNVTVYNGQLDLIVDTIGQESWVQKLKWPQLSRFNQLKWKALYTNPKSSETSAFVKSYENLAFYWILKAGHMVPADQGDMALKMMRLVTQQE
What is the function of this protein?
May be involved in vascular wall and kidney homeostasis.
What are the official names of this protein?
Retinoid-inducible serine carboxypeptidase, Serine carboxypeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCST_SALPK
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQLDEHHAVRTDAGMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKTGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPYAIDITVRDDLSLIAVQGPNAQEKAATLFTDQQRHAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIAMPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTIAWEPADRDFIGREALEMQREKGHEQLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPAGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: CHO_ECO57
Sequence: MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIADEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPLLSGNYEITELDPANDQRAS
What is the function of this protein?
Incises the DNA at the 3' side of a lesion during nucleotide excision repair.  Incises the DNA farther away from the lesion than UvrC.  Not able to incise the 5' site of a lesion.  When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA.  Then UvrC makes the 5' incision.  The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity).
What are the official names of this protein?
Excinuclease cho, Endonuclease cho, UvrC homolog protein.
Protein: PUR9_CLOB1
Sequence: MIKRALISVFDKTGILDLAKFLESRDVEIISTGGTYKHLKENGVKVIDIEEVTGFPEMLDGRVKTLNPLIHGGILAIRDNEEHMKVIEEKGINPIDMVVVNLYPFFNKVEENLSFDEKVEFIDIGGPTMIRAAAKNFKDVVVLTDTKDYENVINEIKENNQVNIQTRKKLAGKVFNLMSAYDAAISNFLLEEEYPEYLTLSYKKNMDLRYGENPHQTAAYYTSTVGKYPMKNFEKLNGKELSYNNIKDMDIAWKTVCEFEEVACCALKHNTPCGVAIGDTVQEAYTKAYECDPISIFGGIVAFNRKVDKETAENLAKIFLEIVVAPDFDEDALEVLKNKKNLRVIKCEEKSTEGKDMAKVDGGILVQKSDNKLLEDTKVVTEKSPTEQEMKDLIFGMKVVKYVKSNAIVVVKDGMAKGIGGGQVNRIWAAKEALDRAGDGVVLASDAFFPFGDVAEEAAKWGIKAIIQPGGSIRDEESIKVCNEKGISMVFTGIRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CAPAR_DROME
Sequence: MNSSTDPTFSELNASFTNTPDTLFATSVSSDPSHGFGEEDYACGTFNCSPKEFVAFVLGPQTLPLYKAVLITIIFGGIFITGVVGNLLVCIVIIRHSAMHTATNYYLFSLAVSDLLYLLFGLPTEVFLYWHQYPDLFGMPFCKIRAFISEACTYVSVFTIVAFSMERFLAICHPLHLYAMVGFKRAIRIITALWIVSFISAIPFGLLSDIQYLNYPLDHSRIEESAFCSMSPKIVNEIPVFEVSFCIFFVIPMILIILLYGRMGAKIRSRTNQKLGVQQGTNNRETRNSQMRKKTVIRMLAAVVITFFVCWFPFHLQRLIFLYAKNMDNYLDINEALFSIAGFAYYVSCTVNPIVYSVMSRRYRVAFRELLCGKAVGAYYNSGFARDHSSFRESSAYDRVHSVHVRASQHPNKFETDSSSANRVLIKKTYSLPLPKNADSTVLSTTDIVIVLENSHTVCEEPKVENDIWIENEETCI
What is the function of this protein?
Acts as a receptor for the neuropeptides CAP-1 and CAP-2, but not CAP-3.  Probably a component of signal transduction pathway that leads to Malpighian tubule fluid secretion in response to these ligands.
What are the official names of this protein?
Neuropeptides capa receptor, Cap2b receptor, Capability receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXB_LEGPL
Sequence: MNILADALLPGLDSAFPPPFTVTLYHKADEIPELLHHKDVLLCRSTLKINGDLLKHHQIKVVATATSGTDHIDFPFLESQNISIIDAKGCNATSVADYVVACLAYLDKQQLIQGKTAGIIGLGQVGTKVYERLNAAEFQLCLYDPPKATRDTSFQSCSLEDLLECDFLCVHAELHSNAPYPSLNLINRDFLKELKPGCIIINASRGGIINEEALLHLGSAILYCTDVYNNEPHIDNRIVSRATLCTPHIAGHSLEAKFAAVAIVSRKLHQMLGLPYPQFATPEKPYRLNDDSNWRELALSIYNPIHETLELKHAGNLSSAFLTLRKNHHHRHDFTTYFDSDSIKKYPLLG
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHO2_YEAS6
Sequence: MSSCKTTLSEMVGSVTKDRGTINVKARTRSSNVTFKPPVTHDMVRSLFDPTLKKSLLEKCIALAIISNFFICYWVFQRFGLQFTKYFFLVQYLFWRIAYNLGIGLVLHYQSHYETLTNCAKTHAIFSKIPHNKDANSNFSTNSNSFSEKFWNFIRKFCQYEIRSKMPKEYDLFAYPEEINVWLIFRQFVDLILMQDFVTYIIYVYLSIPYSWVQIFNWRSLLGVILILFNIWVKLDAHRVVKDYAWYWGDFFFLEESELIFDGVFNISPHPMYSIGYLGYYGLSLICNDYKVLLVSVFGHYSQFLFLKYVENPHIERTYGDGTDSDSQMNSRIDDLISKENYDYSRPLINMGLSFNNFNKLRFTDYFTIGTVAALMLGTIMNARFINLNYLFITVFVTKLVSWLFISTILYKQSQSKWFTRLFLENGYTQVYSYEQWQFIYNYYLVLTYTLMIIYTGLQIWSNFSNINNSQLIFGLILVALQTWCDKETRLAISDFGWFYGDFFLSNYISTRKLTSQGIYRYLNHPEAVLGVVGVWGTVLMTNFAVTNIILAVLWTLTNFILVKFIETPHVNKIYGKTKRVSGVGKTLLGLKPLRQVSDIVNRIENIIIKSLVDESKNSNGGAELLPKNYQDNKEWNILIQEAMDSVATRLSPYCELKIENEQIETNFVLPTPVTLNWKMPIELYNGDDWIGLYKVIDTRADREKTRVGSGGHWSATSKDSYMNHGLRHKESVTEIKATEKYVQGKVTFDTSLLYFENGIYEFRYHSGNSHKVLLISTPFEISLPVLNTTTPELFEKDLTEFLTKVNVLKDGKFRPLGNKFFGMDSLKQLIKNSIGVELSSEYMRRVNGDAHVISHRAWDIKQTLDSLA
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RADI_CHICK
Sequence: MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVRKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQSKYGDYNKEIHKLGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLRQIEEQTMKAQKELEEQTRRALELDQERKRAKEEAERLEKERRAAEEAKAALAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEASEWQHKAFAAQEDLEKTKEELKSVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSSDGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRGKYKTLRQIRQGNTKQRIDEFEAM
What is the function of this protein?
Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
What are the official names of this protein?
Radixin.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Protein: XXT5_ARATH
Sequence: MGQDGSPAHKRPSGSGGGLPTTTLTNGGGRGGRGGLLPRGRQMQKTFNNIKITILCGFVTILVLRGTIGVGNLGSSSADAVNQNIIEETNRILAEIRSDSDPTDLDEPQEGDMNPNATYVLGPKITDWDSQRKVWLNQNPEFPSTVNGKARILLLTGSPPKPCDNPIGDHYLLKSVKNKIDYCRLHGIEIVYNMAHLDKELAGYWAKLPMIRRLMLSHPEVEWIWWMDSDALFTDILFQIPLARYQKHNLVIHGYPDLLFDQKSWIALNTGSFLLRNCQWSLDLLDAWAPMGPKGPIRDEAGKVLTAYLKGRPAFEADDQSALIYLLLSQKDTWMEKVFVENQYYLHGFWEGLVDRYEEMIEKYHPGLGDERWPFVTHFVGCKPCGSYADYAVERCLKSMERAFNFADNQVLKLYGFSHRGLLSPKIKRIRNETVSPLEFVDKFDIRRTPVETKPQN
What is the function of this protein?
Probable xyloglucan xylosyltransferase involved in the biosynthesis of xyloglucan in roots.  May act in association with XXT1 and XXT2 (PubMed:18557833).  Associates with other xyloglucan-synthesizing enzymes to form multiprotein complexes for xyloglucan synthesis in the Golgi (PubMed:25392066).
What are the official names of this protein?
Probable xyloglucan 6-xylosyltransferase 5, Putative glycosyltransferase 5, AtGT5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 34 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: PBPX_STRPN
Sequence: MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDIKKITLTLGD
What is the function of this protein?
A transpeptidase that forms peptide cross-links between adjacent glycan strands in cell wall peptidoglycan (PG).  Part of the divisome machinery that synthesizes the septal cross wall.  Beta-lactams inactivate the PBPs by acylating an essential serine residue in the active site of these proteins.
What are the official names of this protein?
Penicillin-binding protein 2x, PBP-2x, PBP2x.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CATA_STAES
Sequence: MSKQDGKLTGLFGAPVSDRENSMTAGQRGPLLMQDVYYLEQISHFDREVIPERRMHAKGSGAFGTFTVTNDITQYTNAKIFSEVGKQTEMFARFSTVSGERGAADLERDIRGFALKFYTEDGNWDLVGNNTPVFFFRDPKLFISLNRAVKRDPRTNMRSAQNNWDFWTGLPEALHQVTILMSDRGMPKGFRNMHGFGSHTYSMYNDKGERVWVKYHFRTQQGIENYTDEEAAKIVGMDRDSSQRDLYNAIENGDYPKWKMYIQVMTEEQAKNHPDNPFDLTKVWYKKDYPLIEVGEFELNRNPENYFLDVEQAAFTPTNIVPGLDYSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGVENLCPFSRDGQMRFLDNNQGGGPHYYPNNQGIYESQPEHKKPPFPTDGDGYEYNYRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMDGVSKDVKVRHIRHCYKADPEYGKGVAKALGIDINQIDLETNQDETYENFK
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: ILVY_SALTY
Sequence: MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLGQPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTLDQQGPSLSGELHIFCSVTAAYSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSMLENLAVVLIAPALPCPVRNQVSVDKPDWSTVPFIMADQGPVRRRIELWFRRHKISNPQIYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCAQKKRLHEPLIDAFWKILPN
What is the function of this protein?
This protein activates the transcription of the IlvC gene in the presence of acetolactate or acetohydroxybutyrate.  IlvY is also a negative regulator of its own expression.
What are the official names of this protein?
HTH-type transcriptional activator IlvY.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKN1_CALS4
Sequence: MIGRMLGNRYEILEKIGEGGMAKVYKAKCHLLNRIVAIKILRPEFAADENFVKKFKRESQAAASLSHPNIVGIYDVGQEGDIYYIVMEYVKGRTLKELIRENGGPLEVKRAVEIASQVCRALDHAHKNKIIHRDIKPQNILVTDEDVVKVTDFGIARAANGATITYTGDVIGTAYYFSPEQAKGSIVDERTDIYSLGIVLFEMLTGKVPFEGDSPISVALKHIQEDILPPSRLNEKVPEELDKIVLKATQKDPNLRYQTASEFLKDLDTFLKNPKDLKFEEKDFEKTKVMPSREAEELKRAALKREREKKRKEIRKKVGIVLLVLLLLASLSYGTVYVLNNFFKVNDVVVPNVVGLSLSQASKVLSEHNLKMEISEERYSDKPENTILEQDPPQGALVKPGTTVYVVISKGRQMVIVPNVIGRDYLEAKNVLENAGLKVNIIENYNEQYQKGYVFDQNPRYGVQVEYGTTIDVYVSKGPKPSIVPNVVNMNLDEAKASLESAGLTLGKVIYKEADNVPENTVLEQSVPPDTEVQKGSPIDLIVSKLPQNSLQQQTKNVIINLPNKDGPMKVEVYVIQDGQKNLVYSGEHTSSDSPLTVPVTAHKGKAVIEVDIDGQVYSRVEARF
What are the official names of this protein?
Probable serine/threonine-protein kinase Sps1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: OR1A_DROME
Sequence: MSKLIEVFLGNLWTQRFTFARMGLDLQPDKKGNVLRSPLLYCIMCLTTSFELCTVCAFMVQNRNQIVLCSEALMHGLQMVSSLLKMAIFLAKSHDLVDLIQQIQSPFTEEDLVGTEWRSQNQRGQLMAAIYFMMCAGTSVSFLLMPVALTMLKYHSTGEFAPVSSFRVLLPYDVTQPHVYAMDCCLMVFVLSFFCCSTTGVDTLYGWCALGVSLQYRRLGQQLKRIPSCFNPSRSDFGLSGIFVEHARLLKIVQHFNYSFMEIAFVEVVIICGLYCSVICQYIMPHTNQNFAFLGFFSLVVTTQLCIYLFGAEQVRLEAERFSRLLYEVIPWQNLPPKHRKLFLFPIERAQRETVLGAYFFELGRPLLVWIFRTAGSFTTLMNALYAKYETH
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Involved in the behavioral responses to butanal, heptanal, and 2-heptanone.
What are the official names of this protein?
Odorant receptor 1a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or1a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACYP_CHLAA
Sequence: MDLVRAHVFISGRVQGVSFRAYTRDRAREAQVKGWVRNLSDGRVEAVFEGTRPAVQKLISWCYSGPSQAQVERVEVHWEEPTGKEGIFTIVW
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: 3SA12_DABRR
Sequence: LECNKLVDIAYITCPAGKNL
What is the function of this protein?
This three-finger cytotoxin shows cytotoxicity and direct nephrotoxicity.  The cytotoxicity has been observed on B16F10 melanoma cells (EC(50)=2. 56 uM) (PubMed:16997639) and on kidney proximal tubular epithelium LLCPK1 cells (EC(50)=4. 79 uM); it is due to necrotic cell death and not to apoptosis.  Direct nephrotoxicity has been deduced from binding to LLCPK1 cell line and to kidney membranes.  In addition, after intravenous injection into mice tail vein, the toxin principally accumulates in kidney, but only minimally in blood, liver and brain (PubMed:17499831).
What are the official names of this protein?
7.2 kDa cytotoxin RVV-7.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: PDXA2_CUPNH
Sequence: MSDYLPVIGITMGDATGIGPEVIVKSLAHDSVRAQCRPLVIGDVRRLEVAGRLVGSPLKLRAIQAPEEARFQSGTIDCIDLGLIPEGLPFGKLSAVAGDAAFRYIERAVALTRDEKIDAICTAPLNKEALHAGGHKFPGHTEMLAYLTGTPEVSMMLVAPKLRVIHVTTHIGLLDAIRKIEPGLVQRTIERGHQTLQRAGIAAPRIGVCGINPHAGENGLFGHGEEEEKIIPAVEALRARGRDVEGPLPADTLFYRAGRGDFDLVVAMYHDQGHGPVKVLGLEAGVNITVGLPVIRTSVDHGTAFDIAGKGIADERSLLEALRQGAELATRRA
What is the function of this protein?
Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).  Can also use 4-hydroxy-L-threonine 4-phosphate as substrate.
What are the official names of this protein?
D-threonate 4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family. PdxA2 subfamily.
Protein: PAR6B_HUMAN
Sequence: MNRSHRHGAGSGCLGTMEVKSKFGAEFRRFSLERSKPGKFEEFYGLLQHVHKIPNVDVLVGYADIHGDLLPINNDDNYHKAVSTANPLLRIFIQKKEEADYSAFGTDTLIKKKNVLTNVLRPDNHRKKPHIVISMPQDFRPVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRTSGSSGQSTDNSLLGYPQQIEPSFEPEDEDSEEDDIIIEDNGVPQQIPKAVPNTESLESLTQIELSFESGQNGFIPSNEVSLAAIASSSNTEFETHAPDQKLLEEDGTIITL
What is the function of this protein?
Adapter protein involved in asymmetrical cell division and cell polarization processes.  Probably involved in formation of epithelial tight junctions.  Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly.  The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
What are the official names of this protein?
Partitioning defective 6 homolog beta, PAR-6 beta, PAR-6B.
What is the protein family that this protein belongs to?
Belongs to the PAR6 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Cell junction, tight junction.