PharMolix/UniProtQA huggingface dataset:
Protein: SFL1_YEAST
Sequence: MSEEETVSAPAPASTPAPAGTDVGSGGAAAGIANAGAEGGDGAEDVKKHGSKMLVGPRPPQNAIFIHKLYQILEDESLHDLIWWTPSGLSFMIKPVERFSKALATYFKHTNITSFVRQLNIYGFHKVSHDHSSNDANSGDDANTNDDSNTHDDNSGNKNSSGDENTGGGVQEKEKSNPTKIWEFKHSSGIFKKGDIEGLKHIKRRASSRNNSSINSRKNSSNQNYDIDSGARVRPSSIQDPSTSSNSFGNFVPQIPGANNSIPEYFNNSHVTYENANHAPLESNNPEMQEQNRPPNFQDETLKHLKEINFDMVKIIESMQHFISLQHSFCSQSFTFKNVSKKKSENIVKDHQKQLQAFESDMLTFKQHVMSRAHRTIDSLCAVNAAATAASVAPAPAPTSTSAYAPKSQYEMMVPPGNQYVPQKSSSTTNIPSRFNTASVPPSQLFVQYQPQSQQHVTYAKQPAHVPNFINQPIPIQQLPPQYADTFSTPQMMHNPFASKNNNKPGNTKRTNSVLMDPLTPAASVGVQGPLNYPIMNINPSVRDYNKPVPQNMAPSPIYPINEPTTRLYSQPKMRSLGSTSSLPNDRRNSPLKLTPRSSLNEDSLYPKPRNSLKSSISGTSLSSSFTLVANNPAPIRYSQQGLLRSLNKAANCAPDSVTPLDSSVLTGPPPKNMDNLPAVSSNLINSPMNVEHSSSLSQAEPAPQIELPQPSLPTTSTTKNTGEADNSKRKGSGVYSLLNQEDSSTSSADPKTEDKAAPALKKVKM
What is the function of this protein?
Involved in cell surface assembly and regulation of the gene related to flocculation (asexual cell aggregation).  Mutations in SFL1 causes constitutive cell aggregation.
What are the official names of this protein?
Flocculation suppression protein, Protein SFL1.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRAA_YERPA
Sequence: MKYDTSDLCDIYHEEVNVVEPLFSNFGGRTSFGGKITTVKCFEDNGLLFDLLEENGLGRVLVVDGGGSVRRALINAELAELALKNEWEGIVVYGAVRQVDDLAELDIGIQAMAAIPVGAADEGVGESDIRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTOF_DANRE
Sequence: MALVVHLKTVTELRGKGDRIAKVTFRGLSFFSRVLENCEDEARFEQAFRWPIGSQVDGDEMLEIQVFNYSKVFTNRLIGTFRMVLQKVVEEGHLEVSDTLIDDNNTAIQTTISIEIKYQTMDGSVKVWSDGEFLDIPDDLDGTFQFETDSLLSGRSQSSGTSPGRSIHGIPTFRKAGKGVFSAMKLGKTRTSKDDHKKGDDAAILDAEDLDRKAMRLGGILDPDTISLASVTAVTTNVSNKRSKPDIKMEPSSGRPVDYQISVTVIEARQLVGLNMDPVVCVEIGEEKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKIIKISVIHSKNLLRSGTLVGTFKLDVGTVYTQPEHQFHHKWAMLSDPDDITTGCKGYVKCDIAVVGKGDNIKTPHKASEADEDDIEGNLLLPEGVPSERQWARFYVKIYRAEGLPKMNTSIMANVKKAFIGENRDLVDPYVLVQFAGQKGKTSVQKSSYEPIWNEQVIFTEMFPPLCRRLKVQIRDSDKVNDVAIGTHFIDLRKVSNDGDKGFLPTMGPAWVNMYGSTRNYTLMDEHQDLNEGLGEGVSFRARLLISIAVEILDTTSAEIMSSTEVHMEPVSNISESATGKMEEFFLFGSFLEATMIDRKIGDKPISFEVTIGNYGNQIDGVSKPALAKKKKEGGGESEEEESELIHNSSEEEAEDDGDLTSVPSTPPMKPVITDRNYFHLPYFEKKPCIYIKSWWQDQRRRLYNSNIMDKIADKLEEGLNDVQEIIKTEKAYPERRLRGVLEELSTSCSRFVTLANKDQNLSGRTKLDRERLKSCMREMESMGQQAKTIRTQVKRNTVRDKLKLVLNFLQRLRFLADEPQHSIPDVFIWMISNNKRIAYARIPSKDILYSIVDEEMGKDCGKVKAVFLRLPGKKGFGPAGWTVQAKLEMYLWLGLNKQRKDFLIGLPSGFEENKAVKGIGIQAVPPISLVYNMKQVFQLRAHMYQARSLFAADTSGLSDPFARVFFSTHSQVTEVLSETLCPTWDQLLVFDNVELYGEAGELRDDPPIIVIELYDQDTVGKAEFIGRTFAKPLTKMVDEHYGPPRFPPQLEYYQIYRGNCAAGDLLAAFELLQIGPAGRAALPPIDGPTDSDRGPILPVPLGIRPVLSRYRIEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSALIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYILVGSHAVTTLRKFIYSPPDKTANNWAHTGDIVVNMSPEPNIKKMDTVVKIEATTDAVVKVDLNEDEKEKEKKKKKKKKGEEVEEEEPDESMLDWWSKYFASIETMMENLRAQEAAQAEAEEREDLEIAAESAEIKADDFPMKGTKPKEKSKDKKSTKDKKKNNDGTEKRPPKPKVDELMVYNKELESEFGSFEDWLHTFNLYRGKAGDDDDHNVVDEDRIVGRFKGSLCMYKLPLSEEITREAGFDPNMGMFQSIPHNDPINVLVRIYIIRATDLHPADINGKADPYIVIKLGKSDIRDKENYISKQLNPVFGKSFDIEATFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRYYSKHRATCGIASNYSVHGYNVWRDPQKPAQILAKLCKEGKLDGPHYGPGGRVKVANRIFLGPTEIEDESGLKKQTEEHLALTVLRHWEEIPRVGCKLIPEHVETRPLLNPDKPGIEQGRIEMWVDMFPMDVPAPGPAIDISPRKPKRYELRVIIWNTDEVILEDDDYFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFVFPFDYLMAEEKIVISKKESMFSWDETEYKIPARLTLQVWDADHFSADDFLGAIELDLNKFPRGAKTAKQCSLDMVLKEHELPTISIFKQKRVKGWWPFVAQNENDEFELTGKVEAELHLLTAEEAEKSPVGLGRNDPEPLEKPNRPDTSLMWFMNPLRSIRYFIWHNYRWLILKALALLLLLLLVGLFLYSIPGYLVKKLLGA
What is the function of this protein?
Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion and in the control of neurotransmitter release at these output synapses.
What are the official names of this protein?
Otoferlin, Fer-1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the ferlin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Presynaptic cell membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Note=Detected at basolateral cell membrane with synaptic vesicles surrounding the ribbon and at the presynaptic plasma membrane in the inner hair cells (IHCs) at postnatal day 30 (P30). Colocalizes with GPR25 and RAB8B in inner hair cells.
Protein: SYFA_BACLD
Sequence: MQEELKRLEKEAVEKVEAAGSLKEVNDVRVAYLGKKGPITEVLRGMGKLSAEERPKMGALANEVREKIAAAIAEKNARLEEEEVKRKLKEQTIDVTLPGSPVKTGARHPLTIVIEEIEDLFISMGYSVEEGPEVETDYYNFEALNLPKEHPARDMQDSFYITEDTLMRTQTSPVQTRTMEKHKGKGPVKIICPGKVYRRDNDDATHSHQFMQIEGLCVDRDISMSDLKGTLETVAKKMFGEEREIRLRPSFFPFTEPSVEVDVSCFKCGGKGCSVCKQTGWIEILGAGMVHPNVLEMAGFDSKQYQGFAFGMGVERIAMLKYGIDDIRHFYTNDVRFLSQFKQA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLMA_SHEWM
Sequence: MAASPKINRREHILQCLATMLETNPGQRITTAKLAAEVGVSEAALYRHFPSKARMFEGLIDFIEESLLSRINLIMDEEKDTMKRCQHLLQLLLIFAERNPGISRLLNGDALLGEHDRLRSRIGQIFSKIETHLKQILREKTLREGKGFNLDEAILANLLLAVAEGRISQFVRSEFKQKPTTHFEEQWVFIQQQLLQS
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: OR1S1_HUMAN
Sequence: MKTFSSFLQIGRNMHQGNQTTITEFILLGFFKQDEHQNLLFVLFLGMYLVTVIGNGLIIVAISLDTYLHTPMYLFLANLSFADISSISNSVPKMLVNIQTKSQSISYESCITQMYFSIVFVVIDNLLLGTMAYDHFVAICHPLNYTILMRPRFGILLTVISWFLSNIIALTHTLLLIQLLFCNHNTLPHFFCDLAPLLKLSCSDTLINELVLFIVGLSVIIFPFTLSFFSYVCIIRAVLRVSSTQGKWKAFSTCGSHLTVVLLFYGTIVGVYFFPSSTHPEDTDKIGAVLFTVVTPMINPFIYSLRNKDMKGALRKLINRKISSL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 1S1, Olfactory receptor OR11-232.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VEGFA_PROFL
Sequence: MNFLLTWIHWGLAALLYFHNAKVLQAAPAQGDGDRQQSEVIPFMTVYERSVCRPIETMVDIFQDYPDEVEYILKPPCVALMRCGGCCNDEALECVPTELYNVTMEIMKLKPYQSQHIHPMSFQQHSKCECRPKKETRIIQEKKSKREKGKGQKRKRKRGRYKPQNFHCEPCSERRKHLYKQDPLTCKCSCKFTDSRCKSKQLELNERTCRCEKPRR
What is the function of this protein?
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth.  Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
What are the official names of this protein?
Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_CHRVO
Sequence: MTIHQLINERVQAALAAAGAPDAPAVVQPASKPEFGDYQANGVMGAAKALKTNPRALAEKVVAALDLAGIADKVEIAGPGFINIHLAPEYLARRSEAALKDDKLGIAPVKPLRVMVEYSSPNLAKEMHVGHLRSSIIGDALARVMEYVGHDVVRANHVGDWGTQFGMLVAYLVETRHAGDADLQLSDLETFYRNAKIRFDESEDFANTARDYVVKLQGGDEEVLKLWRQFVDVSLKHCEDVYEKLNVGLKREHVRGESSYNDDLPVIVQELREKGLLTEDDGAQVVFLDEFRTQEDKPMGVIVQKKDGGFIYTTTDIGAVRYRHRELKLDRVIYVVDARQSQHFAQMFTICRKAGFAPEAMKLEHVGFGVMMGDDGKPFKTRSGGTVKLIELLNEAEERAYALVSEKNPDLSDAQKREIANAVGIGAVKYADLSKNRMSDYIFNWDTMLAFEGNTAPYLQYAYTRVQSVFRKAEDYDANARIVITEPAEKQLAAALAQFEDTLNSVVEGCYPHYLSLYLYQIATLFSRFYEACPILKSEGEVRASRLQLAALTAKTLRTGLDLLGIKVLESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHL1_KLULA
Sequence: MGKNFHHPYQPYDIQTQLMEHIYELLNSGKKVGIFESPTGTGKTLSLICSTVTWLREHKLEKLNSKVDNDNLSDSTFSSSDDEPEWVNQFYNDKIMKEKSKSLQEYENYLEGLSMSNIKPVLRQLDIGDRKRKKTVPRHIEIEIEDDETNFLPEPYEQDSVSNQNDYEKGQINDEIQKLLAKIDKGYDVKTENNMELKSPLKIYFSSRTHSQLTQFASQLTLPSFPPSSPTLEKERIKFLPLASRKQLCIHAKVSKLKSDLINDACVETVKRQECQFYTNSRDLISSKQFRDYTFSEISDIEDLVQLGHSLHVCPYYSSRTALEGAEIVTLPYQHILSFEIRESLGINLKDSIVIIDEAHNLMDTITSIYSCEISLSDIKICKKLMKIYLNKFKRKLNGKNRVNIMKLMKLLDILQAFIESHFEKGKEISPQSMFRDSNADLLNIHELVTYMRGSKIAYKIDSYADSKLKSDESNTNSVKQPILFKISKFVLSLSNPSFEGSFFFEEGMIIKYMLLEPNQIFKTIVNDSKCVILAGGTMQPTSEFIENLLPFVPSKDIVQFSCNHIIPESNLDTFIVSEGFNFNYESRNNESVMCKLYDFLLELGCRVPHGIVVFFPSYGYLEHVIKFWQLEEIFEKLSMNKRIFYETPGGSDILPQYSSTILDKKKGAFLFSVVGGKLSEGINFQDNLARAVVMVGLPYPNLYSSELLVKKRHIEQKVISAGGSLKDAKSATIEFYENICMKAVNQSIGRAIRHANDYACIYLVDNRYLNNKVQHKLSEWVRKRVKSELKTSEIFAQTSVFFASNR
What is the function of this protein?
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity).  May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).  Has a specific role in chromosome segregation during meiosis II (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase CHL1, Chromosome loss protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDK_PSEU2
Sequence: MAVQRTFSIIKPDAVAKNVIGEITTRFEKAGLRVVASKLKQLSKAEAEGFYAEHSARGFFGDLVAFMISGPVVVQVLEGENAIALNRELMGATNPKEAAAGTIRADFADSIDANAVHGSDSEAAAAREISYFFAATEVTAR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_CLOPS
Sequence: MVDNKDFNEELKESIQEELDNETKSENPNIDEEVEEVSEDIKADEKVIDFEELKALKEENTMFKSKTKKLENELEALKDRLLRISSEYENYRKRTDKEKERIYTDACEDVLIKMLPVLDNLERALAVDGTVEDLKKGVEMTVRQFEDALEKLQVEEISTENGFDPELHQAMMVVEQEGSEPNQVAQVFQKGYKRGDKVIRHSMVTVTK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PACER_MOUSE
Sequence: MVSQSIGWGDSPVDLCEGSNRAFQDTDQPACQLDVRLLRHKASWINPLCVQQPLQELCPQRPTVQSSENHVVLDTPSPLRLSILSYRDSLAEMPLSENTADVICSNSAHCSGGKEGDFFLATEEQEVHLQQESLLKNPKTVATSPSPKEGSARSESPHLTASTDDGDARSSSRSHAWNFFPLETFMLPADVEKENLHFYAADIIISVIENMKCNLPNQQQPERWDTEDASRLRGTGAEMTFYTHIKQEPGSSASSHTGCEGCAALQVSPVAETLSYCPVAGEACKHDLNKLVMLELGKYNDITKGCRCSYNSSKSATCESNLSPAGCLARELFRGFCKCWMLSEVNCQLPGSPTTASSGVGDEEYAEEDFDSSVDAAREVMLKSRVPGTEDWVLPRCQIILTVHPPIKRDIAVVAQNFFCAGCGTPIQPKFVKRLRYCEYLGKYFCASCHSSAESCIPARILTMWDFRKYQVSDFSKWLLDSVWHQPVFKLLGGHHSLYAKAKELDRVKDLQEQLFHIKKLLKTCRFADSVLKEFEQVPSHLTDECHIFSMDDFLRTKKGLLAPLLKDILRASLAHVDSCELCQGKGFICEFCQSTTVIFPFQTTTCRRCAACRACFHKQCFQSSRCPRCARIIARRQHLESLPTAAT
What is the function of this protein?
Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy.  Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex (By similarity).  Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes (By similarity).  Binds phosphoinositides phosphatidylinositol 3-phosphate (PtdIns(3)P), 4-phosphate (PtdIns(4)P) and 5-phosphate (PtdIns(5)P) (By similarity).  In addition to its role in autophagy, acts as a regulator of lipid and glycogen homeostasis (PubMed:30704899).  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Protein associated with UVRAG as autophagy enhancer, Pacer, Protein Rubicon-like.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Note=Associates with late autophagic structure. Recruitment to autophagosome membrane is promoted by autophagic stimuli.
Protein: AP5B1_MOUSE
Sequence: MGPLGREAWAQRLGAFRASPSAFLAGAEGEDLGRDLLSDLRSEKLSEQTKVSLLTLSLEYSDKLWPDAPAAEAAATSLLDTLVLLPTRPSALRRLLLLAATTALVSGDALGPTSGASCRLLPLLLGLASGRDLGRSFGTPSEQRHLQATACECLGELERCKPGLLAGALGMLRSLPGQTGPIQPVSLLLALVLHDTLVVQSRSGAGLQGLLVAEDFSTGSCPWDWTLAEEWDAHLKPQGPSWPTAGEEERGFPVLEPSPEDARELKAAVAQLLDTSYLLTPVAQAQLLWLLGWALRGLRGQPPVLFKPQLVRLLGTAQLTLLHSVLSLKAAFGEALFTAQDEALLLRRLTLGAQHPALPSPTHLFYLHCILSFPENCPLGPEGEEAAPLLLGPQLCRGLMPSLLHDPTVLLARLHLLCLLCADDEEEEKDQTQGPQWFLQEVLAGLQQRAALDGGPRALATLCFQASYLVTNCLTRHSTVQTFLIRGLAQLYRARPSLAPHFVDLLDQVSPELREPLREVLLQEAVARPGESEALCWHLQMLAKVAEGATQSTTLSFLQAAAVHCTDWGLHQALLRVCRALLRTGGGDGLANLLQELARQLENADGRDHARLYYVLLSHLSSSKLGMALGPSLAAPALASSLMAENQGFSSALMVQETSAPIQLSVGPQQAKGPLPVLCLQVQALDAPVYSLELRFRVEGQLYEPLEAVHIPCLRPGQPAHPLYLLLQPRCPAPARLHVRALYSTSAGLTCHARLPPLSVNFADLFLPFPRLPKGSELRFFDELWNSCLPKGVESRVWCPLGQQGLEALVSQYLEPFVVLAQPPTTYLIAIRLPPASMLLLRLEKAQVDGVPVALRTDDWAVLPLVGDYLRGLAAH
What is the function of this protein?
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.
What are the official names of this protein?
AP-5 complex subunit beta-1, Adaptor-related protein complex 5 beta subunit, Beta5.
Protein: SSB1_LACLA
Sequence: MINNVVLVGRLTRDPELRHTPQNQAVGTFGLAVNRQFKNANGEREADFINCVIWRQQAENLAKFAKKGALIGITGRIQTRNYENQQGQKVYVTEVVADTFQMLESNKTQGQQTSKPQAQNKKPQAPDPFKAPAADPFAGGTEISDDDLPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: RS3_SALPB
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: EX7S_STRE4
Sequence: MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKDLQKTLQAAEKTLVKVMQADGTELEMDA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAG_VILV1
Sequence: MAKQGSKEKKGYPELKEVIKATCKIRVGPGKETLTEGNCLWALKTIDFIFEDLKTEPWTITKMYTVWDRLKGLTPEETSKREFASLQATLACIMCSQMGMKPETVQAAKGIISMKEGLQENKEAKGEKVEQLYPNLEKHREVYPIVNLQAGGRSWKAVESVVFQQLQTVAMQHGLVSEDFERQLAYYATTWTSKDILEVLAMMPGNRAQKELIQGKLNEEAERWVRQNPPGPNVLTVDQIMGVGQTNQQASQANMDQARQICRQWVITALRSVRHMSHRPGNPMLVKQKNTESYEDFIARLLEAIDAEPVTDPIKTYLKVTLSYTNASTDCQKQMDRTLGTRVQQATVEEKMQACRDVGSEGFKMQLLAQALRPQGKAGHKGVNQKCYNCGKPGHLARQCRQGIICHHCGKRGHMQKDCRQKKQQGNNRRGPRVVPSAPPML
What is the function of this protein?
Encapsulates and protects viral dimeric unspliced genomic RNA (gRNA).  Binds these RNAs through its zinc fingers.  Acts as a nucleic acid chaperone which is involved in rearrangement of nucleic acid secondary structure during gRNA retrotranscription.  Also facilitates template switch leading to recombination.
What are the official names of this protein?
Gag polyprotein.
What is the protein family that this protein belongs to?
Belongs to the Ovine/caprine lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Matrix protein p16]: Virion. SUBCELLULAR LOCATION: [Capsid protein p25]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p14]: Virion.
Protein: Y339_METJA
Sequence: MKKRGRCSLTNYANAKALVEKILEDLKNNGIKVKSPLSKIQDFHCEADFSVEIENRVAYVDATFTFDKLPNEDLVEKIEAVMTTYNSYLERIDFESDYTKLEFRSVR
What are the official names of this protein?
Uncharacterized protein MJ0339.
Protein: KPYK_DEBHA
Sequence: MSNASLSWLTKLNTSETPDKVLRRSSIIGTIGPKTNNVDVLVKLRKAGLNIVRMNFSHGSYEYHQSVIDNAKQSEEIYKGRPLAIALDTKGPEIRTGTTIDDKDYPILPNHEMIFTTDEAYAKKCDDKVMFIDYKNITKVIEAGKIIYIDDGVVSFEVLQIVDDKTLKVRSVNSGKICSHKGVNLPGTDVDLPALSEKDKADIKFGVKNGVHMIFASFIRTGDDIKEIRKVLGEEGKDIQIIAKIENQQGVNNFDEILVETDGVMVARGDLGIEIPAPQVFVVQKQLIAKCNLAAKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPFEAVSMMHNTAIIAEKAIAYQPLHNEIRSLANRPTPTTETCAMASVSAAYEQDAKAIVVLSTSGFTSRLVSKYKPNVPVMMVTRNHRAARYCHLYRGVYPFVYEKKTVDNWQEDVENRLRWAVSEAIDLGIIKKGDSIVTIQGWTRGSGHSNTVRVVQA
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: THIC_SALAR
Sequence: MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLISGTKDHPQYEENEAIPVYDTSGPYGDPNIAINIQQGLAKLRQPWIEARADVETLSNRSSAYTRERLTDEGLNALRFTGLLTPKRAKAGHCVTQLHYARNGIVTPEMAFIAIRENMGRERIRSEVLRHQHPGENFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDDAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAWHDETLPHESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMANMSESFRAKGGEIYLKREEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: UCRI_CYAP4
Sequence: MAQLSGTPDVPDMGRRQFMNLLTFGSATGVALGMLYPVVRYFIPPASGGVGGGVVAKDALGNDISVSDFLAKHPANDRALAQGLKGDPTYIVVQDDHTIGDYGLNAVCTHLGCVVPWNISENKFICPCHGSQYDNTGKVVRGPAPLSLALAHAAVSDDKITFTPWTETDFRTGKEPWWT
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, ISP, RISP, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: RL28_BACFN
Sequence: MSKICQITGKKAMIGNNVSHSKRRTKRTFDLNLFNKKFYYVEQDCWISLSLCAAGLRIINKKGLDAALNDAVAKGYCDWKTIKVVG
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PNPH_HUMAN
Sequence: MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS
What is the function of this protein?
Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (PubMed:9305964, PubMed:23438750).  Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine (PubMed:9305964).
What are the official names of this protein?
Purine nucleoside phosphorylase, PNP, Inosine phosphorylase, Inosine-guanosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family.
What are the subcellular locations of this protein?
Cytoplasm.