PharMolix/UniProtQA huggingface dataset:
Protein: NACA_EMENI
Sequence: MADPRIEELPDEEVPKTNVEDAADSSESEAGEEPTIPGGAAVTIHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKNILFVINQPDVYRSPSSNTWIIFGEAKIEDLNSQAQASAAQQLAAAEAAGEHAGHDHDHDKGKGKAPETEAKKEEEEDDGEEVDETGLEPKDIDLVMAQANVSRKKAVKALRENDNDIVNSIMALSI
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  Egd2 may also be involved in transcription regulation (By similarity).
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: SC2B2_HUMAN
Sequence: MRVTSATCALLLALICSVQLGDACLDIDKLLANVVFDVSQDLLKEELARYNPSPLTEESFLNVQQCFANVSVTERFAHSVVIKKILQSNDCIEAAF
What are the official names of this protein?
Secretoglobin family 2B member 2, Secretoglobin-like protein.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GEOB_CASDE
Sequence: MTIDHQHIFVGGQWIAPKSTQRSNILNASTEELVGSVPKCNNEDMDRAVAAAREAMRSLAWAGLDGKGRAQHLRRFADAVERRGQQLARSVSLQNGMPINVADQLESAFVVSLLRYYASLAENLVEEEARPSPTGSTTLVRRDPVGVVGAIIPWNFPVALSIFKIAPALAAGCAVVVKPSSGTVLDSYVLAEAAAEAGLPPGVINWVPGDRGIGSHLVSHPGVDKVAFTGSTSAGRIIAEACARLLRPVTLELGGKSAAIVLEDADLDALIRSLPMSSVLNNGQACFSCTRILAPAGRYDEVVDAIAGAVSAYSVGDALDRATVVGPMASAAHRDSVQRYIELGTGEARLVVGGGRTSQDRGWFVQPTVFADVDNRSRIAREEIFGPVLSIIRYEGEDEAVEIANDSEYGLGGTVWSTDHDHAVTIARRMETGTVGINGYMPDLNAPFGGVKSSGMGRELGPESIGAYQRYKSVYLLG
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of geranial to geranic acid.  Is involved in the anaerobic degradation of the monoterpene beta-myrcene.  Seems to be specific for the trans-isomer geranial, since it does not act on the cis-isomer neral.
What are the official names of this protein?
Geranial dehydrogenase, GaDH, Geraniol oxidation pathway protein B.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: CDC42_PIG
Sequence: MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
What is the function of this protein?
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.  In active state binds to a variety of effector proteins to regulate cellular responses.  Involved in epithelial cell polarization processes.  Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase.  Regulates cell migration.  In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity).  Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons.  Facilitates filopodia formation upon DOCK11-activation (By similarity).  Upon activation by CaMKII, modulates dendritic spine structural plasticity by relaying CaMKII transient activation to synapse-specific, long-term signaling (By similarity).  Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups (By similarity).
What are the official names of this protein?
Cell division control protein 42 homolog.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, dendrite. Note=Localizes to spindle during prometaphase cells. Moves to the central spindle as cells progressed through anaphase to telophase. Localizes at the end of cytokinesis in the intercellular bridge formed between two daughter cells. Its localization is regulated by the activities of guanine nucleotide exchange factor ECT2 and GTPase activating protein RACGAP1. Colocalizes with NEK6 in the centrosome. In its active GTP-bound form localizes to the leading edge membrane of migrating dendritic cells.
Protein: OSMY_ECOLI
Sequence: MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVDSSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEAVKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRHVKVETTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK
What are the official names of this protein?
Osmotically-inducible protein Y.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL18_ANAMM
Sequence: MEPAMSLCDLKRATRRKRRVRLKLRSLSSVRLSVFKSNRHFYAQLIDDEKGATLAAASTLEPDVLATAKRRVNSEAARVVARLFAGRLDGLDANYRKFVLDRGSCRYIGVVAAFADELRSLGFEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PDC2_YEAST
Sequence: MLSIQQRYNICLMAERHPKWTQLELAKWAYETFQLPKIPSQGTISRLLARKSTYMNCKEHEKDANRLRKPNNLLVRKILQEWISQSLWNGIPITSPIIQDTAQAVWHRIPAEHREGNGSFSYKWISNFLSKMDVNISVLDEELPKTPKVWTFEERDVLKAYFSKIPPKDLFTLDEAFLSYNLPLDYAQYEASSIQRRIEVATVMLCSNLDGSEKLKPVVVGKYDSYKSFRNYFPNEPNDPVSQSMLGTKMAKKFDISYHSNRKAWLTSNLFHNWLVRWDKRLVAVNRKIWIVLDDSCCHRIINLRLQNIKLVYTSSNSKFLPFNWGVWDEFKTRYRIQQYQALIDLQNRISKNIQNKNKSERNECIPNGKKCLISFEQSQLTMSNAFKFIKKAWDDIPVDAIKANWKSSGLLPPEMIHLNENVSMAFKKNEVLESVLNRLCDEYYCVKKWEYEMLLDLNIENKNTNFLSTEELVESAIVEPCEPDFDTAPKGNEVHDDNFDVSVFANEDDNNQNHLSMSQASHNPDYNSNHSNNAIENTNNRGSNNNNNNNGSSNNINDNDSSVKYLQQNTVDNSTKTGNPGQPNISSMESQRNSSTTDLVVDGNYDVNFNGLLNDPYNTMKQPGPLDYNVSTLIDKPNLFLSPDLDLSTVGVDMQLPSSEYFSEVFSSAIRNNEKAASDQNKSTDELPSSTAMANSNSITTALLESRNQAQPFDVPHMNGLLSDTSKSGHSVNSSNAISQNSLNNFQHNSASVAEASSPSITPSPVAINSTGAPARSIISAPIDSNSSASSPSALEHLEGAVSGMSPSSTTILSNLQTNINIAKSLSTIMKHAESNEISLTKETINELNFNYLTLLKRIKKTRKQLNSESIKINSKNAQDHLETLLSGAAAAAATSANNLDLPTGGSNLPDSNNLHLPGNTGFF
What is the function of this protein?
Essential for the synthesis of pyruvate decarboxylase.  May be important for a high basal level of PDC gene expression or play a positive role in the autoregulation control of PDC1 and PDC5.
What are the official names of this protein?
Protein PDC2.
Protein: RL29_HAES1
Sequence: MKAQELRTKTVEELNAELVNLLGEQFKLRMQAATGQLQQTHQLKQVRRSIAQVKTVLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CBPC5_RAT
Sequence: MELRCGGLLFSSRFDSGNLAHVEKVETVPSDGEGVGGAATAPTSGSASSPDYEFNVWTRPDCAETEYENGNRSWFYFSVRGGTPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPSRPRWERIRERPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQDLLSQLDQRFPENYSAHSSPLDSIYYHRELLCYSLDGLRVDLLTITSCHGLRDDREPRLEQLFPDVGTPRPFRFTGKRIFFLSSRVHPGETPSSFVFNGFLDFILRPDDPRAQTLRRLFVFKLIPMLNPDGVVRGHYRTDSRGVNLNRQYLKPDAVLHPAIYGAKAVLLYHHVHSRLNSKNPSNQQPSSLHLPPEVPLSDLEKANNLHNELHLGQSPDGENHDRWTETEPTEEKTDPVWIMPQPIPELEEPAPDAIPPKESGVAYYVDLHGHASKRGCFMYGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFSEKNMYARDRRDGQSKEGSGRVAIYKASGIIHSYTLECNYNTGRSVNSIPAACHDNGRASPPPPPTFPSRYTVELFEQVGRALAIAALDMAECNPWPRIVLSEHSSLTNLRAWMLKHVRNSRGLTSTANVGLNKKRGSRTPPKSNNGLPVSCSENALSRARSFSTGTSTGGSSSQQNSPQMKNSPSFPFHGSRPAGLPGLGSSTQKVSHRVLGPVREPRCPDRRRRQQQQQQQQQQQQQQQQQPLNQRSTTSSLAPSPTLASASPTSSRNMGSCLLPNSLSLSGSSCPFSSSGDKPEAVMVIGKSLLGAGARIPCIRTRLQTCQRRVSARRGPGFPRLGPGWAGAHRRLAEG
What is the function of this protein?
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins.  Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin.  Cleaves alpha- and gamma-linked polyglutamate tubulin side-chain, as well as the branching point glutamate.  Also catalyzes the removal of alpha-linked glutamate residues from the carboxy-terminus of alpha-tubulin.  Mediates deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation.
What are the official names of this protein?
Cytosolic carboxypeptidase-like protein 5, ATP/GTP-binding protein-like 5, Protein deglutamylase CCP5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody. Note=Mainly cytoplasmic. Slight accumulation in the nucleus is observed. Colocalizes with alpha-tubulin in the mitotic spindle and with midbody microtubules in the intercellular bridges formed during cytokinesis.
Protein: FCPE_PHATR
Sequence: MKFVVFASLLASAARFAPAQQSARTSVATNMAFENELGAQPPLGFFDPLGLVADGDQEKFDRLRYVEIKHGRISMLAVAGYLVQENGIRLPGDIDYSGTSFESIPNGFAALTTISGAGIAQIVAFIGFLELAVMKDITGGEFVGDFRNDFIDFGWDSFDEETKMQKRAIELNQGRAAQMGILALMVHEQLGVSLIPN
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.  Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
What are the official names of this protein?
Fucoxanthin-chlorophyll a-c binding protein E, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fucoxanthin chlorophyll protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein. Note=FCPs are probably transported across the endoplasmic reticulum membranes that surround the plastid via a signal peptide, followed by translocation across the thylakoid membrane via a transit peptide.
Protein: PSAC_ANTAG
Sequence: MAHSVKIYDTCIGCTQCVRACPTDVLEMISWDGCKANQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGSETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn (By similarity).
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: UBIE_SALA4
Sequence: MVEDSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRMVGETGKVILADINDSMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTEKEKALRSMFRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHILPRIGSMVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PHS_XANOR
Sequence: MTDLIPLEQAHCLPRKGSDHKLGEARLAELLPQVPGWELAEAGMALTRTFRFADYYHTLAFVNALAWIAHREDHHPDLGVHYDRVVVRYSTHDVGGLSENDFICAAKTARLYDQGITA
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: MNMG_CERS4
Sequence: MRVFHVKHFDVVVIGGGHAGCEAAAAAARMGVQVALFTLRKSGLGVMSCNPAIGGLGKGHLVREIDALDGIMGRAADEAGIQFRLLNRKKGPAVQGPRAQADRRLYREAVQRLLAAQPGLTVIEGEVVDLQVNGGRVQGVSLADGTSVWAGRVILTSGTFLNGIIHIGDQRRPGGRMGDDPSQRLAAVLGELSLARGRLKTGTPPRLDGRTIRWTELEMQPGDEDPVVFSFLNRAPKARQIACGITHTNARTHQIVRDNLSRSAMYGGHIEGVGPRYCPSIEDKIVRFADKEAHQVFLEPEGLDDDTVYPNGISTSLPAEVQEAYVRTIAGLEDVRILQPGYAIEYDYFDPRELRPTLEVKALGGLYFAGQINGTTGYEEAAAQGLAAGLNAALSIREREPLHFSRSGSYLGVMIDDLTSRGVTEPYRMFTSRAEFRLSLRADNADQRLTPIGLDLGCVSDARRESFNRKRELLEKGRALLEGSSFTPSQLNELGIQVSQDGMRRTAFAVMAFGEEAASAVARGVEGYGDLPEEIRQQLAKDGLYAQFILRQEEEAAALKRDEAIRIPADFDYAPLSGLSSELKSKLMRARPSTIAQAAQLEGMTPSALTLILARLRRAGRDAAAV
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_VIBCM
Sequence: MAKLNAYFGEFGGQFVPQILVPALDQLEQAFIDAQQDDAFRAEFMSLLQEYAGRPTALTLTQNITKGTKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKHEIIAETGAGQHGVATALACALLGLKCRVYMGAKDVERQSPNVFRMRLMGATVIPVHSGSATLKDACNEALRDWSASYETAHYLLGTAAGPHPFPTIVREFQRIIGEETKNQILAREGRLPDAVIACVGGGSNAIGMFADFIEEESVRLIGIEPAGKGIHTHQHGAPLKHGKTGIFFGMKAPLMQDEHGQVEESYSVSAGLDFPSVGPQHAYLNAIGRAEYESITDDEALDAFQALARNEGIIPALESSHALAHAIKMAYAEPDKEQLLVVNLSGRGDKDIFTVHKLLEDKGAL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: IML2_MAGO7
Sequence: MSLRSWFRGSGTTTPKSSAGPSRATTPPSGVQGTVMTAEQQELADLSDAMQAMAHIMNDDPESAEAHLRQRKDPSSFHLLGLGVSIFMRSILGFEKDVMAEASKCIADCETRSWNDKVKGERREPATDGRLFPNGSEFAIVYAQALLMNAVVSVLHESLTDALKAFYKLRKAMAVMSSISAAEEKIMKEQGASSARGNPFEQASTASGSGNLAAEDEDSDLEFVDADEKVSPEAPIHVTYDGHTSTKDSTSQPATDAATLEGKLQALEIPDDSDTKSHLSKSAVESQVPSLSASRAPSPGPPPQLTDAASDGSLFTHPIDIFIHSAINMCYGSLMLVLSMVPPAFSRLLGIIGFRGDRDKGLHMLWQSAAHPNMNGAVAGLLLLGYYHGLLAFADVLPSERDVAELAEPDEIVGYPRGRCIELLRVMRERYPASGLWRMEQARVLIGEKKLKEGIEMLEKCGDAKMRQVTALSTFELAVSSICYLDWPRMHSSFVRMVELNDWSHALYYFIAGCAHLEMYRDAVHELGGLSELSEDGSESEKEVKAGDVKVTATKDRLDVEDIRKKELISNARKYKKSAETLFRKAPTTAGRKRFMARQMPFEVFVMRKVAKWEERATALKLDLADAIGPSPAAEMIYLWNGGKRMNLELIEKAMTILEWDRCTSSATVAKVKEEHDEVAIHGVGQAALLRHAGRGDEAKGILLDISAYDRATCKGGNKDDYILASATYELAMLAWDDVCRPERWPTDADEVEEFRRKKTEECYTLLETVAKWETYVLDARFGMRVQTGLDTVRWLSKKKGWTL
What is the function of this protein?
Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins.  Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
What are the official names of this protein?
Inclusion body clearance protein IML2.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized exclusively in cytoplasmic inclusion bodies under protein folding stress conditions.
Protein: MYCT1_HUMAN
Sequence: MRTQVYEGLCKNYFSLAVLQRDRIKLLFFDILVFLSVFLLFLLFLVDIMANNTTSLGSPWPENFWEDLIMSFTVSMAIGLVLGGFIWAVFICLSRRRRASAPISQWSSSRRSRSSYTHGLNRTGFYRHSGCERRSNLSLASLTFQRQASLEQANSFPRKSSFRASTFHPFLQCPPLPVETESQLVTLPSSNISPTISTSHSLSRPDYWSSNSLRVGLSTPPPPAYESIIKAFPDS
What is the function of this protein?
May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator.  Does not seem to significantly affect growth cell capacity.  Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).
What are the official names of this protein?
Myc target protein 1, Myc target in myeloid cells protein 1.
What is the protein family that this protein belongs to?
Belongs to the MYCT1 family.
What are the subcellular locations of this protein?
Nucleus. Note=Expressed in nuclei of hepatocellular carcinoma cell line BEL-7402 cells.
Protein: RL34_LACLS
Sequence: MKRTYQPHKKSRKTTHGFRSRMATKNGRRVLAARRRKGRASLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NPL1A_XENLA
Sequence: MANIDNKGQTELDQQDMEDVEDVEEEETGEDANSKARQLTAQMMQNPQVLAALQERLDDLVGTPTGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHELERKYAALYQPLFDKRSDIINATYEPTEEECEWKVEEEDISGDLKEKAKLEEEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMLQEHDEPILKHLKDIKVKFSDAGQPMSFTLEFYFEPNEFFTNEVLTKTYKMRSEPDESDPFSFDGPEIMGCTGCLIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVPNDSFFNFFTPPEVPENGELDDDAEAILTADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEADDEEGEEEADEDNDPDYEPKKGQNPAECKQQ
What is the function of this protein?
Acts as a chaperone for the linker histone to facilitate deposition of histone B4 onto linker DNA (PubMed:14550533, PubMed:15811954, PubMed:15928086, PubMed:16982648).  Required for both remodeling of sperm chromatin into nucleosomes, and linker histone binding to nucleosome core dimers.  Plays a role in tissue-specific gene regulation.  Required for primitive hemopoiesis, acting upstream of tal1/scl (PubMed:14550533, PubMed:15811954, PubMed:15928086, PubMed:16982648).
What are the official names of this protein?
Nucleosome assembly protein 1-like 1-A, xNAP1L-A, Nucleosome assembly protein 1, NAP-1, NAP1, xNAP-1, xNAP1.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic prior to the midblastula transition, becoming predominantly nuclear subsequently.
Protein: ATG21_KLULA
Sequence: MALKLLGFNQDATCFSVISSNKGVTIYNCDPFGKCFELEKSTSNDEELDFLVEMLFSTSLIAVVDKTIGASKRKKLKIVNTKRKATICELTFPHEIMDVIMNRKIICVVLKSDQIFVYDISCMKLLRTIDVRGEKLKSTSKFRNSEAVGDIGVRVSLSTDNNSILCYSSYSKSDKENAPLNDIVVFDALKCIQINVLPAVHQSNIVCIACSPDGMLMATASEKGTIIRVFKTIDTENDEPILVNEFRRGSRPSRISEMKFNHDNTLLACVGESDTIHIFALPVTTTEADANEDDTLQQSSHSLSSSINGLQYISKGLANRFGKIIVSKIPTQSQQRHVAYIKIPENAKYRIGFPKDTTNTIHICGEDGNYLVYSIPRNEVGPCTLVKSNTFD
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) vesicles formation and mitophagy.  Involved in binding of phosphatidylethanolamine to ATG8 and in recruitment of ATG8 and ATG5 to the pre-autophagosomal structure.  Protects ATG8 from ARG4-mediated cleavage (By similarity).
What are the official names of this protein?
Autophagy-related protein 21.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=Vacuolar and perivacuolar punctate structures.
Protein: RL3_STRP1
Sequence: MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETDGYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEAGDVVDVTGISKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAGRMGGNRVTVQNLEIVQVIPEKNVILVKGNVPGAKKSLITIKSAVKAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MNTH_STAA2
Sequence: MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURG_LACPL
Sequence: MRLMISGGGTGGHIYPALALIDALKAHDPEAQVQFVGTHRGLESRIVPERGIDFKTIKIQGFKRSLSLQNVKTVYLFLKSVVTARKYIKAFKPDVVVGTGGYVSGAVVFAASQMHIPTVIHEQNSVVGVTNKFLSRFVDKIAISFESARSQFPAQKVVMTGNPRAQQVANIKKSGALAQFDLDPDIPTALIFGGSRGAARINAAAVAAIPELNKRDYQTLFVTGQVHYEKIRNGLSATALAPNVKIEPYIKNMPAILPEVAVILGRAGATSIAEITALGIPSILVPSPYVTNDHQTKNAQSLVNAGAAELIKEADLTGTSLVAALDGLLQSTTHRETMAANAKKLGMPDAADQLLHVLETVIK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSMH_SHEON
Sequence: MSQEFAHLSVLLEETVGGLNIKDDGIYIDGTFGRGGHSRQVLQRLGEKGRLIAIDRDPQAIEAAKQFADDPRFQIVHGGFGQLADYVEDLGLVGKIDGVLLDLGVSSPQLDDAERGFSFLRDGPLDMRMDNSQGETAAQWLARAEIEDMAWVFKTYGEEKNARHIARCIAADRDKTPFLRTKDLADLIARITKNKERNKHPATRVFQAIRIYINSELDQIDQALEGALTVLAPQGRLSIISFHSLEDRIVKRFIRRHSQGESVPHGLPITEDQINKSRKLRAIGKAIMPSDEEIERNARARSSVLRIAERLDY
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.