PharMolix/UniProtQA huggingface dataset:
Protein: RL2_RICPR
Sequence: MALKNFNPITPSLRELVQVDKTNLWKGRPLKTLTKGMSKTGGRNQQGRITSWHRGGGHKKLYRVIDFKRKKIDISAIVERIEYDPNRTAFIALIKYDDGEYSYILAPQKLSIGDRVISSQAADIKIGNCLPLKSIPIGTTLHNVEMKIGKGGQIARSAGTSVELVGKDSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRNRWLGWRPHVRGVAMNPVDHPHGGGEGKTSGGRHPVTPWGFSTKGKKTRKNKRTSKFIVKKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: MIAA_CLONN
Sequence: MKQDLFILAGPTAVGKTDISIKLAQKLNGEIISADSMQIYKHMDIGSAKITEAEKEGIPHHLIDFVSPFDEFSVAEFKEKSKNAIKDIASRGKLPMIVGGTGFYIDSLIFNYDFANTYKDEEYREHLKNLASEHGKEYVHELLKDIDEVSYKKLYPNDLKRVIRALEVFKLTGKTISEFNKEQDIFDIPYNVYYFVLNMDRSKLYERINKRVDIMMEKGLIEEVKSLQNMGCTPDMQSMKGIGYKEILYYLDGKLSLDEAVELIKKGSRHYAKRQLTWFRKDNRVNWIDKDQYKDDTEVCNAIEEKFLNLKNNL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: DNAA_BIFA0
Sequence: MNAENLDPATQAQTIWSDTLALIKQNSRLTAREQGWLAGVTAEAVVGTTIILDVENAQTLQVLQTELNEPIIGALEIANGGSPMFPAFKVMPPAQPEPQTTASPEDSGSRAADAQGAAKESVQPDEDSRTPRHSAEQTGDSRPAAAQEREDSAVHMARPDEQTAESHREPEHEPAQQPVTSHYDEAIVQTFEDIDPVAGFGPSVAGTTAPQYPPQSEMQGSFTPGVTGNYRDPVTHLNSNDTFDTFIQGDSNRFARTVALAVAEGSGRDYNPLCIYGGSGLGKTHLLHAIGNYAVQNQKPRPRVLYVTSEEFTNDFIESIRTSGQDNEDPAMEKFYRKYREVDVLLIDDIQFLGGKRGILEQFFHTFNSLYQANKRIVIASDVPPHNLEDFEDRLISRFEQGITVDVKPPNLETRIAILRMLAEQNHIRVPNDVLNLIAERFANNVRELEGALKRVIAMASLNHQPVTRALTERTLQDFFTTDVEVKPTDIIARVAKYFHLTFDDIVGPGRPRSVTLARQIAMYLTRDMTSMSLMNIGQIFGGRDHTTVMHACKHIADKMQEKQEIYNYVNELTVELKQHLND
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSHB2_BACCR
Sequence: MERHVLVVFPHPDDEAYAAGGTIRLLTDQGVPVTYACGTLGQMGRNMGKNVFANRETIPHIRKKELKDACEAMGIKDLRMLGFHDKTLEFEDVDFVADKIEAIIQEVNPSRIITFYPEHGVHPDHNAFGRAVVRAVSRMPKEERPVIHAVAITKNREAVLGEPDVVNNISEVFDHKLTALGAHRSQTEAMLEDTHAKIKNKDAATLKWLQLEQFWTYKWE
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  Catalyzes the second step of the pathway, the deacetylation of N-acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal).  Has weak activity compared with bshB1.
What are the official names of this protein?
Probable N-acetyl-alpha-D-glucosaminyl L-malate deacetylase 2, GlcNAc-Mal deacetylase 2.
What is the protein family that this protein belongs to?
Belongs to the PIGL family.
Protein: ILVC_TREPR
Sequence: MRVLYERDGDVSIIRERVVAVVGYGSQGRAHAMNLRDSGVEVVIGLRPGPSFDAAMSDGFMPRSVQEAVSIADVAMLLTPDECMADVYAKAVRDYLRPGASVAFAHGFNVCYNQIPIGNGVGAFMAAPKAPGHMVRETYIAGWGTPHLVAAKPQCEHLRALAVSYAIANGGGAAGIIETTFVDETETDLFGEQAVLCGGLVELIRAGFDTLVSSGYEPELAYFECMHEMKLIVDVMNRGGVAALNESISNNAEYGEYVSGPRVIGAAVRSAMRRVLNDIRTGRYAKDFIMEGRSNSPTLTACRRAVGEHPIEAVGARLRSRMTCAHGT
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ANGP2_RAT
Sequence: MWQIVFLTFGCDLVLASAYNNFRKSVDSTGRRQYQVQNGPCSYTFLLPETDSCRSSSSPYMSNAVQRDAPLDYDDSVQRLQVLENILENNTQWLMKLENYIQDNMKKEMVEIQQNVVQNQTAVMIEIGTSLLNQTAAQTRKLTDVEAQVLNQTTRLELQLLQHSISTNKLEKQILDQTSEINKLQDKNSFLEKKVLDMEDKHSVQLQSMKEQKDQLQVLVSKQSSVIDELEKKLVTATVNNSVLQKQQHDLMETVNSLLTMMSSPDYKSSVAVPKEEKTTFRDCAEIFKSGLTTSGIYTLTFPNSTEEVKAYCDMDMGGGGWTVIQHREDGSVDFQRTWKEYKEGFGSPLGEYWLGNEFVSQLTSGHRYVLKIQLKDWEGSEAHSLYEHFYLSGEESNYRIHLTGLTGTAGKISSISQPGSDFSTKDSDNDKCICKCSQMLTGGWWFDACGPSNLNGQYYPQKQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADF
What is the function of this protein?
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling.  Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1.  In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression.  In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.  Involved in the regulation of lymphangiogenesis.
What are the official names of this protein?
Angiopoietin-2, ANG-2.
What are the subcellular locations of this protein?
Secreted.
Protein: RBP_BPLSK
Sequence: MTIKNFTFFSPNSTEFPVGSNNDGKLYMMLTGMDYRTIRRKDWSSPLNTALNVQYTNTSIIAGGRYFELLNETVALKGNAVNYIHANIDLTRTANPVSLSAETSNNSNGVDINNGSGVLKVCFDIVTTSGTGVTSTKPTVQTSTLDSISVNDMTVSGSIDVPVQTLTVEAGNGLDLQLTKKNNDLVIVRFFGSVSNIQKGWNMSGTWVDRPFRPAVVQSLVGHFAGRDTSFHIDINPNGSITWWGESIDNTPIATRGNGSYFIK
What is the function of this protein?
Binds to the host phosphopolysaccharides at the onset of infection.  Upon activation by calcium, the receptor binding proteins change their conformation, presenting their binding sites to the host, and a channel opens at the bottom of the baseplate for DNA ejection.
What are the official names of this protein?
Receptor binding protein, RBP, Gene product 18, Gp18.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus receptor binding protein family.
What are the subcellular locations of this protein?
Virion. Note=Part of the baseplate.
Protein: Y1660_BURCH
Sequence: MQVLVDADACPAVIKDMLFRAARRAEICVTLVANQFLRTPPSPFIKAVQVPAGFDVADARIVELAEPGDLVITADIPLAAAVLDKGAHALDPRGNWFSRENIEERLSTRAMMDQLRSAGIDTGGPAPFSARDGKTFASQLDRFLARHAPR
What are the official names of this protein?
UPF0178 protein Bcen2424_1660.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: DEF_PHOV8
Sequence: MILPIYVYGQPVLRKEAEDITPDYPNLKELIANMFETMNRADGVGLAAPQIGLPIRVVTIDLDVMSDDLPEFKDFRRAYINPHILEVGGEEVSMEEGCLSLPGIHEAVKRPDRIHVTYLDEELKEHDEWVEGYLARVMQHEFDHLDGKMFIDHLSALRKQMIKGKLGAMLKGKARCSYKVKTIK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: KXD1_YEAS1
Sequence: MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit KXD1, BLOC-1 subunit KXD1, KxDL homolog.
What is the protein family that this protein belongs to?
Belongs to the KXD1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: ATPG_HAHCH
Sequence: MAVGKEIKTQIASIKSTQKITSAMQLVAASKMRKAQQRMAAGRPYADRIRSVISHIATANPEYRHLYLQEREAKRVGYIVVSTDRGLCGGLNVNAFREMMRSMKEWRDKGAEVDLCAVGQKAISFFRNYGGNVVAALSHLGDDPSLTKIVGSVKVMLDAYAEGKIDRLYLVHNRFVNTMTQKPTVAQLLPLPPAEDDEMIRRHWDYIYEPDAKGLLDGLLTRFIESQVYQAVVENNACEQAARMIAMKSATDNAGGIINELELAYNKARQAAITQEISEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNC_ROSCS
Sequence: MKKPLDELCARLDVTFSDQRLLWQALTHRSFLNERVDERLSLFSNERLEFLGDAIVNFLATTLVFERFPDAGEGYLTAWRAALIRTETLASFARRYDLGSHTLLARGEESSGARQRPSLLADTFEAVVAAIFIDQGLDAVRKFLLPLFEETLATLQEQGLPVDYKSKLQARIQAERGITPRYRMIERSGPEHQPEFTFEALAGDESLGTGRGASKQAAEQDAARDALDRLGGRD
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MERA_PSEAI
Sequence: MTHLKITGMTCDSCAAHVKEALEKVPGVQSALVSYPKGTAQLAIVPGTSPDALTAAVAGLGYKATLADAPLADNRVGLLDKVRGWMAAAEKHSGNEPPVQVAVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPFDGGIAATVPTIDRSKLLAQQQARVDELRHAKYEGILGGNPAITVVHGEARFKDDQSLTVRLNEGGERVVMFDRCLVATGASPAVPPIPGLKESPYWTSTEALASDTIPERLAVIGSSVVALELAQAFARLGSKVTVLARNTLFFREDPAIGEAVTAAFRAEGIEVLEHTQASQVAHMDGEFVLTTTHGELRADKLLVATGRTPNTRSLALDAAGVTVNAQGAIVIDQGMRTSNPNIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEEGSHRLIGVQAVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCCAG
What is the function of this protein?
Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase.  MerA protein is responsible for volatilizing mercury as Hg(0).
What are the official names of this protein?
Mercuric reductase, Hg(II) reductase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Protein: MECP2_HUMAN
Sequence: MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS
What is the function of this protein?
Chromosomal protein that binds to methylated DNA.  It can bind specifically to a single methyl-CpG pair.  It is not influenced by sequences flanking the methyl-CpGs.  Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A.  Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
What are the official names of this protein?
Methyl-CpG-binding protein 2, MeCp-2 protein, MeCp2.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalized with methyl-CpG in the genome. Colocalized with TBL1X to the heterochromatin foci.
Protein: SYK_OCEIH
Sequence: MSEELNEHMQVRRDKLAEHMEKGLDPFGGKFERSHQATDLIEKYDSYSKEELEETTDEVTIAGRLMTKRGKGKAGFAHIQDLSGQIQLYVRKDMIGDDAYEVFKSADLGDIVGVTGVMFKTNVGEISVKAKQFQLLTKSLRPLPEKYHGLKDIEQRYRQRYLDLITNPDSRGTFVSRSKIIQSMREYLNGQGFLEVETPMMHSIPGGASARPFITHHNALDIELYMRIAIELHLKRLMVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMELTENLVAHIAKQVHGSTTITYGEHEINLEPKWTRLHIVDAVKDATGVDFWKEVSDEEARALAKEHGVQVTESMSYGHVVNEFFEQKVEETLIQPTFIHGHPVEISPLAKKNKEDERFTDRFELFIVGREHANAFSELNDPIDQRARFEAQVKERAEGNDEAHYMDEDFLEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDVLLFPQMRTK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEP1_ASPNG
Sequence: LTNKTARFLVNGTSIPEVDFDVGE
What is the function of this protein?
Removes acidic, neutral and basic amino acids as well as proline from the C-terminal position.  Digests preferentially peptides containing a hydrophobic residue in P1' position, as well as arginine, lysine or phenylalanine in P1 position of ester substrate.  Catalyzes also peptide synthesis.
What are the official names of this protein?
Carboxypeptidase 1, Carboxypeptidase I, CPD-I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SODF_METJ
Sequence: AYTLPPLDYAYTALEPHIDAQTMEIHHTKHHQTYINNVNAALEGTSFANEPVEALLQKLDSLPENLRGPVRNNGGGHANHSLFWKVLTPNGGGEPKGALADAIKSDIGGLDTFKEAFTKAALTRFGSGWAWLSVTPEKKLVVESTGNQDSPLSTGNTPILGLDVWEHAYYLKYQNRRPEYIGAFFNVVNWDEVSRRYQEALA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: CH071_HUMAN
Sequence: MATFHRAHATSSVKPRARRHQEPNSGDWPGSYRAGTRCSAIGFRLLHSPQHWRPRSLGAGQGREDPSWEGGALGDLKALWDQPCQPPPWVQLQLSSAYGARQQRWQLSTLPEPPAARTPGQMPQQRLIRAAGPSAAGGGNQWLSPM
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00588.
Protein: RIBB_PSESM
Sequence: MAFDRIEDIIEDYRQGKMVLLVDDEDRENEGDLLLAADCCTAQAISFMAREARGLICLTLTDEHCKSLGLEQMVPSNGSVFATAFTVSIEATTGVTTGISAADRARTVQAAVNPGAVPDDLVQPGHIFPLRARDGGVLTRAGHTEAGCDLARMAGFTPASVIVEVMNDDGTMARRPDLELFAEKHGIRIGTIADLIHYRLSTEHTIVRIGERELPTVHGTFRLFSYEDRIEGGVHMAMVMGDIRREDPTLVRVHVVDPLRDLVGAEYTGPANWTLWAALQRVAEEGCGVVVVLANHESSQALLERIPQLTQPPRQYTRSQSRIYSEVGTGAQILQDLGIGKLRHLGPPLKYAGLTGYDLEVIESIPFPG
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: RNH_SALSV
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFSEGYTLTTNNRMELMAAIVALEALKEHCEVTLSTDSQYVRQGITQWIHNWKKRGWKTAEKKPVKNVDLWKRLDAALGQHQIKWVWVKGHAGHPENERCDELARAAAMNPTQEDSGYQAEA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_MICLC
Sequence: MASKEEILAGLAEIVNEETGLDTAEVQPEKSFTDDLDIDSISMMTIVVNAEDKFGVKIPDEEVKNLKTVQDAVDFIDGAQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_GEOSW
Sequence: MKYDRILIRYGEMTTKGRNRNLFVRRLKDNVAKKLHAFQNIKIEYMRDRMYILLNGEPHEPIIDKLKNVFGIHSFSLAMKCHNELNEIKETALAAVKQLPHEGKTFKISARRVDKQFPYGSSELNYEIGAHILRNTDGLTVNVHDPDIDVRVEVRQEGTYITCHDIPGPGGLPVGSSGKAMLMLSGGIDSPVAGYLAMKRGLEIEAVHFFSPPFTSDRAKQKVIDLVKKLTTYGGKIKLHIVPFTEVQQAIYTQVPNEYSLISTRRAMLKITDALRQRHRALAIVTGESLGQVASQTLESMFVINDVTTTPILRPLVSMDKIEIIDIAKKIDTHDISILPYEDCCTIFTPRSPKTKPKKEKVVHYESFVDLQPLIEKAIANTETMVIDEHSATEDEFEQLF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y686_METJA
Sequence: MELSHDTKNLLDLVKKAYEGEVALPDFQRNFVWTRQDIEELIKSLLENMFIGTFLIQEINPENPPFGTIYIRGAEELNPNITLRKPRILVLDGQQRLTSLFYAIYSPNFPLKNTTKPYAFFIDLNKLVEDDIDNSVFSLSKDCRQYKALLNEDNSFDIEKLKEKRFFPLTFLSNSNKFYKIWYKHFSEIFPEEVFNYMHNILEYKVPTLILGLSYNDKPEQVVVLFERINKTGIKLSPYDLLVARFYKFIKLREKWAEAFENNIRIKNFAGDVEDTKVPYMFIQALALSKGMSIKSRDLIKIDNSILNDESWNRVVDIAENKVFQRIFDISEYGIADIKKWNPYTPTITMMLAFFLKHDIPDMDKVNKWYWSSVFSERYSGSTESKMMKDFKEVSQWIENNNKIPEVVENLKIEIQYGAYSLKKVKSSGSSKYKGVFNLIFKNKPMDFYKPDNIAYYKLEDHHIFPKGFLRNKGISNEYIDSVLNKTPILDETNKKISKKSPSKYVKEMIEIQKNKGLSEDEAVNKVKEILKGHFINEEMFEILRNTDDSLSKDEIEENFNRFIELREKLILEKILELIS
What are the official names of this protein?
Uncharacterized protein MJ0686.
Protein: CAPPA_METS5
Sequence: MRPIPRTMSTQHPDNATVPEWAKGDVIEGEAEVIEAYYAFSRLNVHEVMWDAEGKDVDTHVVRKLFSSFDEYFKNNILGEDIFLTYRLPNPKIEGAERKVFAETMESIPITFDVAERFYGRKVVPVFEVILPFTTNASDIISVARYYERAVAMEENIELQDGVYVRDLVGEIYPKRIEVIPLIEDKDSLLNTRNIIEGYYRAIKPSYMRLFIARSDPAMNYGMLTAVLLAKYALSEAGKLAEELGIPIFPIIGVGSLPFRGHLSPENYQRVMEEYEGVYTFTIQSAFKYDYSEEQVKGAISHINREEVKEPRILGEEEKKVTRDIIETYTLSYQPVIESLANLINTVALHLPRRRARKLHISLFGYARSTGKVMLPRAITFVGSLYSVGLPPEVIGISSLGKLNEMQWNILEENYKFLKNDLQKASEFINPEGLSTLVSYGYLDAEISKKLEEDIKYLESMGVKIGPRSYETKKHALLSQLLMLSLKEKKYNEVKQYAREMAVIRKSIG
What is the function of this protein?
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 2 family.
Protein: HSPB1_MOUSE
Sequence: MTERRVPFSLLRSPSWEPFRDWYPAHSRLFDQAFGVPRLPDEWSQWFSAAGWPGYVRPLPAATAEGPAAVTLAAPAFSRALNRQLSSGVSEIRQTADRWRVSLDVNHFAPEELTVKTKEGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTLVSSSLSPEGTLTVEAPLPKAVTQSAEITIPVTFEARAQIGGPEAGKSEQSGAK
What is the function of this protein?
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state.  Plays a role in stress resistance and actin organization (PubMed:17661394).  Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (By similarity).
What are the official names of this protein?
Heat shock protein beta-1, HspB1, Growth-related 25 kDa protein, Heat shock 25 kDa protein, HSP 25, Heat shock 27 kDa protein, HSP 27, p25.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: RECA_DESPS
Sequence: MVGATAKDKAGSVENAISQIQKQFGKGSIMRLGEQALEAIPVISTGALSLDIALGVGGLPKGRMTEIYGPESSGKTTLALHVVAEAQKLGGIAAFIDAEHALDTAYAEKLGVNIDNLLVSQPDFGEQALEIAEILIRSGGVDIIVVDSVAALTPKAEIDGNVGDVHVGLQARLMSQAMRKFAGVLNRSNTVLIFINQIRMKIGVMFGSPETTTGGNALKFYCSERLDIRRIGAIKDGQEITGNRTRVKVVKNKVAPPFKIAEFDIIYGEGISKIGDMFDLAVGLDIIDKSGSWYSYKNERIGQGRENSKQFLMDTPAICHEIEEKVRSAYGLPDREETKREETAQIPDTEKTKDV
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGTRB_RAT
Sequence: MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
What is the function of this protein?
Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney.  The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.
What are the official names of this protein?
Type-1 angiotensin II receptor B, AT3, Angiotensin II type-1 receptor B, AT1 receptor B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.