PharMolix/UniProtQA huggingface dataset:
Protein: TRMD_STRZP
Sequence: MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKARHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQVYAEDLAQEEELIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSHQDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLLEHYQLTVEEEKMLAEIKENKE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STHA_YERE8
Sequence: MQQHFHFDAIVIGSGPGGEGAAMGLVKQGARVAVIERYNNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDNARTISSSFSDILNHADRVINQQTRMRQGFYDRNHCQMFSGDASFIDANTINVRYADGTNDTLRADNIVIATGSRPYRPANVDFTHERIYDSDTILQLSHEPQHVIIYGAGVIGCEYASIFRGLSVKVDLINTRDRLLAFLDQEMSDALSYHFWNNGVVIRHNEEFEQIEGTVDGVIVHLKSGKKVKADCLLYANGRTGNTSGLGLEKIGLEADSRGLLKVNSMYQTALSHVYAVGDVIGYPSLASAAYDQGRIAAQAMIKGEANTHLIEDIPTGIYTIPEISSVGKTEQDLTAMKVPYEVGRAQFKHLARAQIVGMDTGSLKILFHRETKQILGIHCFGERAAEIIHIGQAIMEQKGEGNTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAE_NOSS1
Sequence: MKSVLPSTPIVTLKPKIEDSFAITFAPLSLEEIHALADDSANGAVVVMSGMVRNQTDGKPVVSLEYQAYEPMALRVFYQIAADIRSAWPAVNRVVIHHRIGRLQVGQISVLVAIGCPHRSEAFAACRYAIDTLKHNAPIWKKEHWQDGSSTWVSIGACEQSGQNC
What is the function of this protein?
Converts molybdopterin precursor Z into molybdopterin.  This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.  The sulfur is provided by MoaD (By similarity).
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, MPT synthase subunit 2, Molybdenum cofactor biosynthesis protein E, Molybdopterin-converting factor large subunit, Molybdopterin-converting factor subunit 2.
What is the protein family that this protein belongs to?
Belongs to the MoaE family.
Protein: RL28_NITWN
Sequence: MSRRCELTAKAPLVGHKVSHSNIKTKRRFLPNLVNVTFVSETLSSSVRFRVSTHALRSVDHRGGFDAFLLKARDSELSPKAIELKRQIQKKQAAKAG
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RNPA_BORDL
Sequence: MKKRNINIKSRLEIQELFKKGQFVKIEGINIFYRFTSLAISRILITFPRVFKGAVKRNRVRRVFKECFREYFTLLKDGCADFIFVVYPQKANINYHEVKTILKNMIVYVIKRKV
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: MURG_RUTMC
Sequence: MSKKILIMAGGTGGHIFPALAIANELKNHSTHIQWLGSNVGIENEIVPKHNIKLHTVNSVGLRGKSVVSLIKALFLLSYATLQIMGIFLKFKPNIVLGMGGFTSGIGGLVACIFRIPLVIHEQNSISGTTNKILNKIAKKTFQAFDDTFIKSATTSGNPIAFSSVDKQTNNKKLNLLIIGGSLGSKPINDISTQLNININIWHQTGRLHFDAVKAQYKNNVVKVTEFIKDMANAYAWADVVLCRAGAMTVSELMLSATPSILIPLPHAIDNHQFYNAKILADSNAGILIEQKDLTIELLEKTLLNINKNQIKQMSTNALKLAKPNAAKQIVNYLLSFD
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2172_STRP8
Sequence: MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVGYVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK
What are the official names of this protein?
UPF0297 protein spyM18_2172.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: ARCC1_ENTFC
Sequence: MGKKMVVALGGNAILSNDASAHAQQQALVQTSAYLVHLIKQGHRLIVSHGNGPQVGNLLLQQQAADSEKNPAMPLDTCVAMTQGSIGYWLSNALNQELNKAGIKKQVATVLTQVVVDPADEAFKNPTKPIGPFLTEAEAKEAMQAGAIFKEDAGRGWRKVVPSPKPIDIHEAETINTLIKNDIITISCGGGGIPVVGQELKGVEAVIDKDFASEKLAELVDADALVILTGVDYVCINYGKPDEKQLTNVTVAELEEYKQAGHFAPGSMLPKIEAAIQFVESQPNKQAIITSLENLGSMSGDEIVGTVVTK
What is the function of this protein?
Catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP.  Can also catalyze, although with low efficiency, the phosphorylation of bicarbonate, leading to the formation of carboxyphosphate, an unstable intermediate found in the reactions catalyzed by carbamoyl-phosphate synthase and biotin carboxylase.  Can also use acetate.
What are the official names of this protein?
Carbamate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CF163_BOVIN
Sequence: MIRNPNYTNFVCCAVCNKIIPPAPFGETFKRIHEYKPFKTRFYTHKDILDIGKDILNKEEQFQEDALKERIAQAEADIWAKADERQRQAVKKALEEANDMYKMQIQFLKEEHEKELKEMATRTKMQLHKNLEEELQREHLAAEQRMVHRIQRIMMECHREKVQAVQEAREQERLMAQEEIQSQRRKAMEELMSSGVTVVKDQKKNVNQLIKEKQHEMNLYYCMTQRQKQEEVQEVLQEAEKTHQAKLGSVMDKLVNTQGELLSIAKQLGIMTNWKDFLEEELQETRAAFQKYINYTFPKLSPGHADFILPERKKTPSNLIIPENQTTPD
What are the official names of this protein?
Uncharacterized protein C6orf163 homolog.
Protein: YBEY_PARXL
Sequence: MSRTPKLTLNLQFPAAKAWPEHKALLPRAAVAGWIKAALFADGELTVRFVDAEEGRTLNRTYRGKDYSTNVLTFAYAESEDDPVTGDLILCCPVVEKEAAEQGKPLVAHYAHLLVHGTLHAQGYDHEVEEEAEEMEAIETEILGKLGFPDPYQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPB4_KLULA
Sequence: MSKSLSWDDLKCEIQPWIRTAIESMGFETMTPVQASTIPLFSGNKDVVVESVTGSGKTIAFVIPILERLIKEEANSAKFKKSHFHSLIISPTRELASQIHDVIEDFLKYYPDNLYPIRSQLLVGTSSASVRDDINSFTDNRPQILVGTPGRVLDFLQKTNVKTASCGTVVLDEADKLLDLNFQKDVETILKMLPKQRRTGLFSATIESAGAQIFKTGMRNPVKVAVKSNSSAPSSLSINYIVIPPKDKLQLLLTLLNNYRFKKCIVYFPTCISVTYFYAFINHLKELNLIQDDLKLFSLHGKLQTQSRMKTLDSFTSNLTDAVLFTTDVAARGIDIPDVDLVIQLDPPTDADIFIHRCGRTGRANRIGKALVFLNEGREEDYVPFLEVKNVKLEEESVELKGVENLTKIFHDWILHDRARFDHSVRAYVAFIKYYSKHTASSIFRFHSMDFIGVANFYGLLRLPRMPEITRYAADQIPEEGWLVSPPVNLDTFAYLDKQKEKARLQELQNLKQISDKKKLKSELKKKNMAWSDKTLTKEAKAERRAAMAIKRKAIEEKLLRGDEESEDEVEQDWKDLVRQNKKKKHNSMQGSFDDL
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase SPB4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YCIC_SALG2
Sequence: MSITAKSVYRDAGNFFRNQFITILLVSLLCAFITVVLGHAFSPSDAQIAQLSEGEHLAGSAGLFELVQNMTPEQQQILLRASAASTFSGLIGNAILAGGIILMIQLVSAGHRVSALRAIGASAPALPKLFILIFLTTLLVQIGIMLIVVPGIIMAIVLALAPVMLVEEKMGVFAAMRSSMRLAWANMRLVAPAVIGWLLAKTLLLLFAPSFAVLTPNVGAVLANTLSNLISAVLLIYLFRLYMLIRQ
What are the official names of this protein?
UPF0259 membrane protein YciC.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBFA_BACAN
Sequence: MKLRANRVGEQMKKELGDIISRKIKDPRVGFVTVTDVQVSRDLQIATVYISVLGDEEQKENTLKGLAKAKGFIRSEIGQRIRLRKTPEISFEFDESIGYGHRIDTLLHEINKEGKREE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS25A_SCHPO
Sequence: MAPKKKWSKGKVKDKAQHATVFDKSIIDRINKEVPAFKFISVSVLVDRMKINGSLARIAIRDLAERGVIQKVDQHSKQAIYTRVPAATA
What are the official names of this protein?
40S ribosomal protein S25-A, S31-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: DAPB_GEOMG
Sequence: MVKIAVCGAAGRMGQRIIVAAKEAGCTVSGALERPGHELVGQDAGLIAGCGALGVAISDDLNAVVDGCDVLIDFTTPKVSLKNLEACALKKKAIVIGSTGFTPEERALAAELAKDIPAVLAPNMSVGVNVCFKILKDVAKTLGDDFDVEIVELHHNKKKDAPSGTAVRMGEVVAEALGRDYNKVANYHREGICGERTKEEIGMQTVRGGDIVGEHTVYFIGMGERIEISHRAMTRDMFSRGSVRAAQWVVGKAPGLYDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOD3_SCHPO
Sequence: MEEWRNFLDIKVINESSLVTVDNLSLQLDISSEKAQEYLNMFYQGNDFLYPIYLIHGQPIDDEINLEIDEESQPISNFPVLQYILCDKSSLQEKQSRLKSGYKTVIFALSSAPLSDFDELLPAVYEIREKDVLYKKEDADKYGFIFNENSVPRVLKKAPSTHSPQLSVPSKTSTIDKTDTRSTEKTKGKDIFSNARNQKGNSSRKNKKAPLENHKEKEPLLPKEEKLSEQAKRERDDLKNIMQLEDESVSTTSVHDSEDDNLDSNNFQLEIGTEAKSAAPDEPQEIIKSVSGGKRRGKRKVKKYATTKDEEGFLVTKEEEVWESFSEDENISTGTSNVVRNKPTTVNIATKKKNTAQSKPQQKSIMSFFGKK
What are the official names of this protein?
DNA polymerase delta subunit 3, Cell division control protein 27.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDTH_EDWI9
Sequence: MSLVLQARRSGKYFLLIDNLLVVLGFFVVFPLISIRFVDQLGWAALIVGIALGLRQLLQQGLGIFGGAIADRVGAKPMIISGMLLRAAGFATMAVASEPWILWASCTLSALGGTLFDPPRTALVIKLTRPHERGRFYSLLMMQDSAGAVIGALIGSWLLAYDFHYVCWAGAALFVLAAAWNAWLLPAYRISTIRAPVREGMLRVVRDRRFLTYVLTLTGYYMLAVQVMLMLPIMVNDIAGGPGAVKWMYAIEAALSLTLLYPIARWSEKRFRLEQRLMFGLLLMTLSLFPLGLSTTLQSLFALICCFYLGSIIAEPARETLSASLADARARGSYMGFSRLGLALGGALGYTGGGWMYDMGRSMNMPELPWALLGIIGMLTLALLYWQFSLQVPCATHQPRSS
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TMUB1_XENTR
Sequence: MIEGLGDEVTVAVGLFILLLAITLAWLSTYVAEGSDPLLGSLIPTGRRDPLLVLSNPVPASPEPQRPAEAQAEKPEEGEQDPGGEQEAGSENANLDQMLDIQGVSKRSHAVPPLREEDGTEQDVTQEDDKEAESPLIVGRKIEQEEEKPLAKEGMTREKPEEALMTVRLKFLNETEEVAMVRPNDTIGMLKSKYFPGQEQQMKLIFQGQLLHDSSQTLCSLHITDNCVIHCHRSQATTPTSSSSPESGGSSQEHTGLTPPIGNLMIPVFVVMLALIWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYGR
What is the function of this protein?
May contribute to the regulation of translation during cell-cycle progression.  May contribute to the regulation of cell proliferation (By similarity).  The membrane form is involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR.  May be involved in centrosome assembly.
What are the official names of this protein?
Transmembrane and ubiquitin-like domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm. Nucleus.
Protein: INO1_BOVIN
Sequence: MEAATEFVVESPDVVYSPETIEAQYEYRTTSVSREGGVLKVHPTSTRFTFRTARQVPRLGVMLVGWGGNNGSTLTAAVLANRLRLSWPTRTGRKEANYYGSLTQAGTVSLGLDAEGKEVFVPFSSLLPMVAPDDLVFDGWDISSLNLAEAMRRAQVLDWGLQEQLWPHMEAMRPRPSVYIPEFIAANQSARADNVIPGTRAQQLEQIRRDIRDFRFSAGLDKVIVLWTANTERFCEVIPGLNDTAENLLRTIQLGLEVSPSTLFAVASILEGCAFLNGSPQNTLVPGALELAWQRRVFVGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGQNLSAPPQFRSKEVSKSSVVDDMVHSNPVLYSPGEQPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDSLLAAPIMLDLALLTELCQRVSFCTDVDPDPQSFHPVLSLLGFLFKAPLAPPGSPVVNALFRQRSCIENILRACVGLPPQNHMLLEHKMERPGLKRVGPLATTSPVLCKKGSAPTAPNGCTGDANGHSQAEAPQMPTT
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner (PubMed:885873).  Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity).
What are the official names of this protein?
Inositol-3-phosphate synthase 1, IPS 1, Myo-inositol 1-phosphate synthase, MI-1-P synthase, MIP synthase.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_BRUA1
Sequence: MTASQDFVVKDISLADWGRKELDIAETEMPGLMAAREEFGKSQPLKGARISGSLHMTIQTAVLIETLKVLGAEVRWASCNIFSTQDHAAAAIAATGTPVFAVKGETLEEYWTYTDQIFQWPDGEPSNMILDDGGDATMYILIGARAEAGEDVLSNPQSEEEEVLFAQIKKRMAATPGFFTKQRAAIKGVTEETTTGVNRLYQLQKKGLLPFPAINVNDSVTKSKFDNKYGCKESLVDGIRRGTDVMMAGKVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAASTADIVVTTTGNKDVITIDHMRKMKDMCIVGNIGHFDNEIQVAALRNLKWTNVKPQVDLIEFPDGKRLILLSEGRLLNLGNATGHPSFVMSASFTNQVLGQIELFTRTDAYKNEVYVLPKHLDEKVARLHLDKLGAKLTVLSEEQAAYIGVTPQGPFKSEHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3421_MYCTO
Sequence: MSRVQISTVLAIDTATPAVTAGIVRRHDLVVLGERVTVDARAHAERLTPNVLAALADAALTMADLDAVVVGCGPGPFTGLRAGMASAAAYGHALGIPVYGVCSLDAIGGQTIGDTLVVTDARRREVYWARYCDGIRTVGPAVNAAADVDPGPALAVAGAPEHAALFALPCVEPSRPSPAGLVAAVNWADKPAPLVPLYLRRPDAKPLAVCT
What are the official names of this protein?
Uncharacterized protein MT3530.
What is the protein family that this protein belongs to?
To M.leprae ML0378.
Protein: VIM2_CARAU
Sequence: GFSLQDELDFLKKLHDEELADVQAQIQDQQVQVDMDMAKPDLTAALRDVRLQYENLATKNIQESEDWYKSKFADMTEAANKSNEALRLAKQEANEYRRQVQALTCEVDALKGTNESLERQMREIEENFAIESSSSQDNIARLEEDIRNMKDEMAKHLREYQDLLNVKMALDIEIATYRKLLEGEESRITTPLPNLSSFNLRDAILETKPILENTFSKKVLIKTIETRDGEVINESTQNHDDLE
What is the function of this protein?
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.  Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
What are the official names of this protein?
Vimentin A2.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: Y2809_CLOBM
Sequence: MRFVIVTGLSGAGKTQAIRSLEDLGFFCVDNLPPTLIPKFAEACYQTEGKIKKIALVIDIRGGKFFDDLFESLKYLKEEGYKYEILFLDASDEVLIKRFKESRRKHPLSPDGRILNGISMERNRLREVKDRADNIINTSELATRELREAINEIYGEQDQIENQLVITVLSFGFKYGIPLDSDLVFDVRFLPNPYYIKELKQYSGKDKKVSDYVMSFDVTNKFVNRLEDMLDFLIPNYFKEGKRQLIISIGCTGGRHRSVAIANAIYEGLKSKGHEVNIDHRDINEDIHKGGKKL
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein CLK_2809.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: MDTO_ECOLI
Sequence: MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVILISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEPLIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCIVVGLYPTLLMTLIGVLWFPSRAISQMHQALNDRLDDAISHLTDSLAPLPETRIEREALALQKLNVFCLADDANWRTQNAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKLASEINKLQHAVAEGQCWQSDWRISESEAMAARECNLENICQTLLQLGQMDPNTPPTPAAKPPSMAADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVGSSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERSSYIGTQMVVTFALATLENVFGPVYDLVEIRDRALGIIIGTVVSAVIYTFVWPESEARTLPQKLAGTLGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVALERQLDSEERALLIERSQTVIRQGRDLLHAWDATWNSAQALDNALQPDRAGQFADALEKYAAGLATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPATEQAQGATQ
What is the function of this protein?
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
What are the official names of this protein?
Multidrug resistance protein MdtO.
What is the protein family that this protein belongs to?
Belongs to the MdtO family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INV1_PEA
Sequence: MAISSIFLLSLFSLIYVIPIEATHHVYQTLETLSSHHSSKSNHQPYRTAYHFQPLKNWINDPNGPMRYGGFYHLFYQYNPKGAVWGNIVWAHSVSKDLVNWTPLDHAIHPSQPSDIKGCWSGSATILPGGKPAILYTGIDPNNHQVQNIAIPKNMSDPLLREWKKSPKNPLMEPTIANKINSSSFRDPTTSWLGKDGFWRVLIGSKIDTKGMAILYKSKNFVDWVEAKHPLHSAEGTGMWECPDFYPVLDKNLLRTGVDTSRNGDDDVRHVLKVSLDDTKHDHYLIGSYDVVKDVFVPENGFEDNGFVLRYDYGKYYASKTFFDDGKNRRILLGWVNESSSVADDVKKGWSGIHTIPREIWLHESGKQLVQWPVKEIENLRMNPVNWPTKVIKGGERISITGVDSVQADVEISFEISDLGKVESLRKWIDPQLLCSQKGAGVKGGVGPFGLLVFASQGLKEYTAVFFRIFKYQDKNLVLMCSDQSRSSLNKDNDMTSYGTFVDVDPLHEKLSLRTLIDHSVVESFGGEGRACVTARVYPTLAIHDKAMLKLTSEY
What are the official names of this protein?
Beta-fructofuranosidase, cell wall isozyme, Acid invertase, Sucrose hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: Y4721_BACC7
Sequence: MISQSTLFLFILLIIGLIAKNQSLTVAIGVLFLLKFTFLGDKVFPYLQTKGINLGVTVITIAVLVPIATGEIGFKQLGEAAKSYYAWIALASGVAVALLAKGGVQLLTTDPHITTALVFGTIIAVALFNGVAVGPLIGAGIAYAVMSIIQMFK
What are the official names of this protein?
UPF0756 membrane protein BCAH187_A4721.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THEM4_XENLA
Sequence: MLRSCARLIYKGITLPRQQQNLHSLPCSYTAPKFYSQEAPRDYGVPNTTWSKNLLDLYNKYMEGSKSGTWKRIPSYNATVHYIKGVPPVRNREKRLFTRNLDQDGVGFEYCMFYNKAERRMVCLFQPGPYLEGPPGFTHGGCIATMIDSTTGAGAVYLCGGVMTANLTVDYKNPIPLGCVVIIDSKVEKIEGRKVFTSCQIRSHDDSMLHTEATALFIKLCP
What is the function of this protein?
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism.
What are the official names of this protein?
Acyl-coenzyme A thioesterase THEM4, Acyl-CoA thioesterase THEM4, Thioesterase superfamily member 4.
What is the protein family that this protein belongs to?
Belongs to the THEM4/THEM5 thioesterase family.
What are the subcellular locations of this protein?
Cell membrane. Cell projection, ruffle membrane. Cytoplasm. Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space. Note=Released from the mitochondria into the cytosol in response to apoptotic stimuli.
Protein: ISPT_PARMW
Sequence: MSRPLATSHDTTPSQLCPPELDGDRLPVHVAVIMDGNGRWAEARGLPRMMGHRAGVEALKSTLRLCSDWGIAALTAYAFSTENWSRPGDEVNFLMTLFERVLQKELRTLEEEQVRIRFLGDLDALPLKLQELIGDATERTAANDGIHFNVCTNYGGRRELVRAAQRLARQAANGDLMPEDIDENSLAAELFTAGEQDPDLLIRTSGEHRISNFLLWQLAYAEIHVTDVFWPDFNAEALKRALLDFQSRSRRFGGLDPLTP
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: DCA12_DROME
Sequence: MFNGMVRTIRDSVVGTYPSCHVSSRLEERRAKQRAMRQERRRKPDKPDDFVTYEDSGSDEETPQQQEEVLNTSYNLCDYLRSRESGLRDRRSVNVEYTSRYVLTHDMLRETQISLGYINKVFCSKWLSSRQVVFGTKCNKLLVYDVNMRRVDAIPTLSNSRANHPEVQGGLHAIELSPSRSFLATGARNSSDIAVYRLPTLDPVCVGEGGHRDLIMGMCWLDDQFLVSGSKDSRMALWRINEDHMEFPDGGEEACPTFATIHPLSVKEVRTAQRIRSLCFNKEFKEIAALSLNGYIHIFNAETFKQTLSRKLPNCQDNVSIAYHSDGLYAVGCRSYTILLDARTLQTIKKITSRYSGCGIRATSFEGNLLTVGTGLGMLLFYDIRAGKYLESSVNASRTVALKCSKGIVYPEDEMDGFQQVKYVPAIYTHCYDSTRMRLFAAGGPLPATLVGNYAGVWQ
What is the function of this protein?
Substrate-recognition component of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation (PubMed:30670470, PubMed:31857346).  Required for synaptic function and plasticity at larval neuromuscular junctions (NMJs) by promoting neurotransmitter release (PubMed:30670470).  The DCX(DCAF12) complex catalyzes ubiquitination and degradation of yorkie (yki), thereby regulating the Hippo/SWH (Sav/Wts/Hpo) signaling pathway (PubMed:31857346).  Acts as a regulator of tissue growth during development: required for the apoptotic elimination of supernumerary cells during metamorphosis (PubMed:26972874).
What are the official names of this protein?
DDB1- and CUL4-associated factor 12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF12 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Presynapse. Note=Mainly localizes to presynapses in larval neuromuscular junctions.
Protein: NU4LM_EUBGL
Sequence: MTLIHMNIIMAFSMSLVGLLMYRSHLMSALLCLEGMMLSLFVLAALTILNSHFTLANMMPIILLVFAACEAAIGLALLVTISNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYSC_SHEB9
Sequence: MTNIVWHQHPVDQAARAEQKGQNPVLLWFTGLSGAGKSTLAGALERALFEAGFHTYLLDGDNVRHGLCKDLGFTVEDRDENLRRVGEVAKLMVDAGLVVLSAFISPTREERDSIRARFPVSQFIEVHVSTPLSVCEQRDPKGLYVKARSGEISNFTGISSPYEAPLAAELTIDTSKGDLVTQVRALIDYLTAINVINADKAKALA
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: FLGH_BRUME
Sequence: MNKAILAVAMVLLLAGCATKPEEIGRAPDLSPVAAHLGMQNNPQFNGYPARPGKASYSLWDQRSSNFFKDPRAATPGDVLTVIISINDRANLDNKTDRERVSKGIYGGGGSFATSSITGAAAGGDMDASVNTHSDSKSKGKGTIERSEDIRLQIAAIVTDTLPNGNLIIRGSQEVRVNNELRVLNVAGVVRPRDISGNNTISYDKIAEARISYGGRGRLSEIQQPPYGQQILDQFSPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.