PharMolix/UniProtQA huggingface dataset:
Protein: FTN_HELPJ
Sequence: MLSKDIIKLLNEQVNKEMNSSNLYMSMSSWCYTHSLDGAGLFLFDHAAEEYEHAKKLIIFLNENNVPVQLTSISAPEHKFEGLTQIFQKAYEHEQHISESINNIVDHAIKSKDHATFNFLQWYVAEQHEEEVLFKDILDKIELIGNENHGLYLADQYVKGIAKSRKS
What is the function of this protein?
Iron-storage protein.
What are the official names of this protein?
Bacterial non-heme ferritin.
What is the protein family that this protein belongs to?
Belongs to the ferritin family. Prokaryotic subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2S1_STRAL
Sequence: MINADKPHRWNDDVQASVRLYNQWFLDAAPKAYRDTRQLTIDEVEQAFQRTANMTSITPEVLKAHPKTLATLRMSTAPPIARDRLVGLSHGSKSLLDTMEKGKLPPRMKGDVLDTHLAKMCAVLTDLLDLDLFHWYPTGEPAEPRQRELAATVVADRLCGAIADPIVRNAQERRQLALIEEWLLARGYTKKTHSASLPLNTMQPGTFSFRQNVVVGSDLPVNIPVDAVIQPHTPHSHKLPILIEAKSAGDFTNTNKRRKEEATKIHQLQLKYGNEISLTLFLCGYFNTGYLGYSAAEGLDWVWEHRIDDLEAAGA
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GTCGAC-3' and cleaves after G-1.
What are the official names of this protein?
Type II restriction enzyme SalI, R.SalI, Endonuclease SalI, Type-2 restriction enzyme SalI.
Protein: NU4LC_CITSI
Sequence: MMLEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINFVTFSDFFDSRQLKGDIFSIFVIAIAAAEAAIGSAIVSSIYRNRKSTRINQSTLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DDX56_MOUSE
Sequence: MEDQEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQSLLHKKATGPVMEQAVRGLVLVPTKELARQAQAMIQQLAAYCARDVRVANVSAAEDSASQRAVLMEKPDVVVGTPSRVLSHLQQNTLKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLPRIYQAFLMSATFNEDVQTLKELVLHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKALLFVNTLERGYRLRLFLEQFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIATDAEILGPQVKGKRRGRGSKGNKASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTARANNPGIVLTFVLPAEQPFLGKIEDLLSGEGEAPILLPYQFQMEEIESFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPAALRGLVHPRKKRRKVPFSRKAKKVKAQNPLRDFKHRGKKPKPAAKPS
What is the function of this protein?
Nucleolar RNA helicase that plays a role in various biological processes including innate immunity, ribosome biogenesis or nucleolus organization.  Plays an essential role in maintaining nucleolar integrity in planarian stem cells (PubMed:32703285).  Maintains embryonic stem cells proliferation by conventional regulation of ribosome assembly and interaction with OCT4 and POU5F1 complex (PubMed:32703285).  Regulates antiviral innate immunity by inhibiting the virus-triggered signaling nuclear translocation of IRF3.  Mechanistically, acts by disrupting the interaction between IRF3 and importin IPO5.  May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits.  Has intrinsic ATPase activity (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX56, ATP-dependent 61 kDa nucleolar RNA helicase, DEAD box protein 56.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACACA_SHEEP
Sequence: MGEPSSLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLSDLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIARRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLCVDWHENDFSKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLARMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLSAHTLLNTVDVELIYEGEKIVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVLRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVEGLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDSLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSSQAFLPPPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPDGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVYSSVPLLNSKDPIDRVIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSARERKELESKLKEREEFLLPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST
What is the function of this protein?
Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis.  This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA.
What are the official names of this protein?
Acetyl-CoA carboxylase 1, ACC1, ACC-alpha.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RIBF_SYNY3
Sequence: MVLRQVMDFAQAVEHLLHPAVVSFNPHPRSFFSGRTQPLLTPLPEKAAQLTAIGIEQLVLLPFTEKLANLSPKQFVQSILVEQLQAKFISVGQDFCFGHQRRGNVQDLQNLGQEFGITVAIAQLEQTDTERISSSRIRRALKEGKLAMANHLLGRPYALRGTVVQGQQLGRKLGFPTANLCLPADKLWPKYGVYAGWVNLNALDVPIPAVINLGDRPTVNGQEPSAEVHLLQWSGDLYGQGLEVALTHYLRPETKFAGLDQLKNQIAQDCQQAEKLLNLDGAIP
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
What are the official names of this protein?
Bifunctional riboflavin kinase/FMN adenylyltransferase, Riboflavin biosynthesis protein RibF.
What is the protein family that this protein belongs to?
Belongs to the RibF family.
Protein: LFTR_XYLFA
Sequence: MHSPPYLLSPAPNTPFPPAEYALREPNGLLAIGGDLTPQRLLAAYRNGIFPWFTEGQPPLWWSPDPRTVFRSDSIHLSRRFRRNLRTSTWTVRADTMFAAVIDACASTPRRGQDGTWITANMREAYLTLHQHSYAHSVEVFDGTMLVGGIYGVALGRMFFGESMFSTRNGASKIALASLAHFLHTHSAPLIDAQVENQHLLNLGAERWPRKDFLAYVRRLITQTDLPACWSVLFGEQLSRELV
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_DEIGD
Sequence: MSGQDKASQRVLCAMSGGVDSSVTAALLKDAGYQVIGAMMRFWPDDKRVDTFDTCCSPDAAYEARRVAEQVGVPFYLLDYREQFQHHIVGPFLSEYAQGRTPNPCVNCNTKVKFDELVKKAKMLGCRYVATGHYVKRVEREDGSVEFHRGDDPRKDQTYFLWGTPREALPFILFPVGELEKPRVREIAAEKGLLTARKPESQNICFVPGKVQDFVAEHLPQRQGLIREIRTGEVVGEHLGTQFYTLGQKKGLGLYQTHRVRHVVHLDPETNTVWVGDYEDCLWTGLKAEGANYLLDLAELPREVEVQVRYRTKPVRATVLHADEHGFELQFEEPQFAVAPGQSAVLYAGTRLLGGGLIADHARNLPVVPADQAAQPVPVSG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y344_STRPS
Sequence: MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHAARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKFNELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYASPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVSEAAVKKIELLMNDLGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKSADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEELGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK
What are the official names of this protein?
UPF0371 protein SPCG_0344.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: GCST_EXIS2
Sequence: MSQTTLKRTPLFDIIAPTGKMVDFAGFEMPVLFSSIKEEHTAVRERVGMFDVSHMGELFVSGSDALAFLQQTLSNDISKIAIGQAQYNVLCQEDGGTVDDLLVYRLDEQDYLLVVNASNIEKDEAHLRQYLTGDVLLENQSDAYGQIAVQGPKAVEVLQELTALKLEDIKFFRFAQGELAGVEMLVSRSGYTGEDGFELYMPSADASAVWNALLEADVVPCGLGARDTLRFEACLPLYGHELSATISPIEAGMGFAVKPQVKSFVGSEVLVKQKEDGPRRQLIGLELTDKGIARQDAPVLVNGETIGFVTTGTLPPTIGKAIALALVPTEYATEETFEIEVRGKKLAAKRIDTPFYRRSK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: SSRP_GLOVI
Sequence: MAGEKTRKILVDNRKARFEYEILETYSAGLALLGTEVKAIRAGRANLNDAFARIHHGEVLLYNMNISPLQTAGAFAHDPLRTRKLLLKRREIHKLTGRVEEKGLTLIPLKLYLEGSWVKLDLGLARGKKLYDKREDIKKRETKRDIERAMRR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HTH_DROME
Sequence: MAQPRYDDGLHGYGMDSGAAAAAMYDPHAGHRPPGLQGLPSHHSPHMTHAAAAAATVGMHGYHSGAGGHGTPSHVSPVGNHLMGAIPEVHKRDKDAIYEHPLFPLLALIFEKCELATCTPREPGVQGGDVCSSESFNEDIAMFSKQIRSQKPYYTADPEVDSLMVQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDTTKPPELGSANGEGRSNADSTSHTDGASTPDVRPPSSSLSYGGAMNDDARSPGAGSTPGPLSQQPPALDTSDPDGKFLSSLNPSELTYDGRWCRREWSSPADARNADASRRLYSSVFLGSPDNFGTSASGDASNASIGSGEGTGEEDDDASGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVYTPHPGPSGYGHDAMGYMMDSQAHMMHRPPGDPGFHQGYPHYPPAEYYGQHL
What is the function of this protein?
All isoforms are required for patterning of the embryonic cuticle.  Acts with exd to delimit the eye field and prevent inappropriate eye development.  Isoforms that carry the homeodomain are required for proper localization of chordotonal organs within the peripheral nervous system and antennal identity; required to activate antennal-specific genes, such as sal and to repress the leg-like expression of dac.  Necessary for the nuclear localization of the essential HOX cofactor, extradenticle (exd).  Both necessary and sufficient for inner photoreceptors to adopt the polarization-sensitive 'dorsal rim area' (DRA) of the eye fate instead of the color-sensitive default state.  This occurs by increasing rhabdomere size and uncoupling R7-R8 communication to allow both cells to express the same opsin rather than different ones as required for color vision.
What are the official names of this protein?
Homeobox protein homothorax, Homeobox protein dorsotonals.
What is the protein family that this protein belongs to?
Belongs to the TALE/MEIS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PIMT_PARL1
Sequence: MNEETSMDEGEQEKIELIMGLRRQGIRDKRVLSALERVPREKFISATFRKQAYEDHALPIECGQTISQPYIVAYMTEQLHVGERMKVLEVGTGSGYQAAVLSRLCRRVYTIERYRTLLKDAVKRLEDLHIHNVTAKVGDGAQGWPEQAPFDRIIVTAAAPSVPQKLVDQLKEGGLMIVPVAVSGARGEQKLVRIERTGDGVKREELLPVRFVPLVEGVAKES
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G1091_BACFN
Sequence: MFKHLNALFIGLALFACTSGAVAQTIKPIETPVPVRPAGQKDVVGLTTPKLDVVRVGFIGLGMRGPGAVERFTHIPGTQIVALCDLIPERVAGAQKILTKANLPEAASYSGSEDAWKKLCERKDIDLVYIATDWKHHAQMAIYAMEHGKHVAIEVPSAMTLDEIWALINTSEKTRKHCMQLENCVYDFFELTTLNMAQQGVFGEVLHTEGAYIHNLEDFWPYYWNNWRMDYNQNHRGDVYATHGMGPACQLLDIHRGDKMNYLVSMDTKAVNGPAYIKKTTGKEVKDFQNGDQTSTLIRTEKGKTILIQHNVMTPRPYSRMYQVVGADGYASKYPIEEYCMRPTQIASNDVPNHEKLNAHGSVPADVKKALMDKYKHPIHKELEETAKKVGGHGGMDYIMDYRLVYCLRNGLPLDMDVYDLAEWCCMADLTKLSIENSSAPVAIPDFTRGAWNKVKGYRHAFAK
What is the function of this protein?
Glycosidase (By similarity).  Has no alpha-N-acetylgalactosaminidase activity.
What are the official names of this protein?
Glycosyl hydrolase family 109 protein 1.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: G1PDH_METB6
Sequence: MSPDAIKLLKEKVFDKSKWMQLPRDVVIGHDVLGQIAPVCEDLKLGRSALLISGKNTMDRAGKTVQDVIGKTCDVMVYISDEISPAVIKDAEKAAKDVDFVIGVGGGRVIDTAKIVSYNLDRQFVSVPTAASHDGIASARASVPTGEGNVSLEAHPPIAIIADTCIIASAPHRLLAAGCADVISNYTAILDWEMAHRIKGEPMSEYAVALSKMTAEILVKNADLIRPNQEQSAWFVTKALVSSGVAMSIAGSSRPASGGEHKFSHALDRLAPNKALHGESCGIGTIISMYLHGGDWRGIRQSLRTIGAPVTPTDVGIADEIAVEALLMAKTIRPERFTIFDMGITRDSAEKLIQMLYAD
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_PETMO
Sequence: MSVVSMKQLLEAGAHFGHRTRRWNPKMQPYIFTARKGIHIIDLQKTLKSIDEAYDFLKNSVMEKKRVLFVGTKKQAQQIVADEARRCGEFFVNNRWLGGLLTNFKTIKSRIDKLEQLTEYVESEEFSKLPKKEQATIRRNLEKLEKNLGGLRGMKKIPDILFIIDPKKEEIAVKEANLLKIPIIATVDTNCDPDVIDYVIPANDDAIRTIMLIVSKMADAIIEGKEGRIETLEESSEVEEEEEEKDEVIDEVDEKLEAEEKYASYAEEVEEVEEEFIPSEIEDEDEKF
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: H2B_ASPCL
Sequence: MPPKAAEKKPSTGGKAPAGKAPAEKKEAGKKTAAAASGDKKKRGKTRKETYSSYIYKVLKQVHPDTGISTRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ISPD_DEHMC
Sequence: MFLNEKVGAVIVAAGQSRRMEGQDKIFALLAGKPVLAHTLSVFQESPQVDDIALVMAEHNIEKAKELVKEYNFSKVIAICSGGTLRQDSVRSGLSALCDCGWILIHDGARPLLEPDSIPEGLEAAKLCGSAIAAVPLKDTIKEISPEGLVEKTLPRERLISVQTPQVFRADIIQKAYQRVGIIATDDAQLVEKLKLPVRIFSGACANIKITTPEDLLMAEILLKKGR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: EFTS_RHIL3
Sequence: MSEITAAMVKELREKTGAGMMDCKKALAETAGDMEAAIDWLRAKGIAKADKKSGRTAAEGLIGVSSQGTKAVVVEVNSETDFVARNDAFQELVRGIAKVAVSTDGTVDAVAAATYPASGKSVSDTIKDAIATIGENMNLRRSVALSVEDGVVATYIHNAVSDGLGKLGVLVALKSTGDKEALNAIGRQVAMHIAATAPLAIRPEEVDAAVAERERNVFIEQSRASGKPDNIIEKMVDGRMRKFFEEVALLSQAFVINPDLTVAAAIKEAEKAVGAPIEVAGMARLLLGEGVEKEETDFAAEVAAAVKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAAA_META3
Sequence: MIVILNNGGQYVHRIHRSLRYLKIPSKIIPNSTPLAEIEENKEIKGIILSGGPDIEKASNCLDIALNSKLPILGICLGHQIIAKAYGGEIGRAESEEYAHSKIFVKEENDLFKNVPKEFTAWASHKDEVVGAPLNFEILAYSNICEVEAMKHKEKPIYGVQFHPEVSHTENGAEILKNFCKVCGLLGE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: Y4PF_SINFN
Sequence: MGASWHQTIRALGSAHHVEVDGSQRHRMCQNEFVEVLNRGKPSVEQIIRIGMDTSKSVFQLHGVNAVEQPILRKKLSRREMVKFFEKTPPTIIALEACGGSHHWARLLSSFGHEVKLIAPQLAKPYVKRGKNDAADAEALCEAMSRPTMRFVPMKTADQQAALMLVGMRERLIRNRTQLANAIRGFAMEFGIVAAKGMCRIEALLERIAADPSLPELAQDLFALHGQEYRELACQIKTLDEKLMKLHRADECSKRLAEIPGVGPIGASLLLMKTPDPRMFKSGRDFAAWIGLTPKDHSTAGKVRLGVITRAGDEMLRSILVVGATSLLQQVRTGRSRHASAWLMGLLQRKRPKLVAVALANKLARIAWKLMTSGESYRQAEGQAQTS
What are the official names of this protein?
Putative transposase y4pF/y4sB.
What is the protein family that this protein belongs to?
Belongs to the transposase 20 family.
Protein: VP2_FCVF9
Sequence: MNSILGLIDTVTNTIGKAQQIELDKAALGQQRELALQRIGLDRQALNNQVEQFNKILEQRVQGPIQSVRLARAAGFRVDPYSYTNQNFYDDQLNAIRLSYKNLFKI
What is the function of this protein?
Minor structural protein present in one or two copies per virion.  Does not seem to play a role in capsid assembly, but is essential for production of infectious virus (By similarity).
What are the official names of this protein?
Protein VP2, Minor capsid protein.
What is the protein family that this protein belongs to?
Belongs to the vesivirus VP2 protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: MLC1_MOUSE
Sequence: MTREGQFREELGYDRMPTLERGRQDAGRQDPGSYTPDSKPKDLQLSKRLPPCFSYKTWVFSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAGSCIPSAIVSFAVGRRNVSAIPNFQILFVSTFAVTTTCLIWFGCKLILNPSAININFNLILLLLLELLMAATVIISARSSEEPCKKKKGSISDGSNILDEVTFPARVLKSYSVVEVIAGVSAVLGGVIALNVEEAVSGPHLSVTFFWILVACFPSAIASHVTAECPSKCLVEVLIAISSLTSPLLFTASGYLSFSVMRVVEIFKDYPPAIKSYDVLLLLLLLLLLLQGGLNTGTAIQCVSFKVSARLQAASWDPQSCPQERPAGEVVRGPLKEFDKEKAWRAVVVQMAQ
What is the function of this protein?
Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.
What are the official names of this protein?
Membrane protein MLC1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum.
Protein: SPT20_SCHPO
Sequence: MERNNGLGDYTYRYHGKELSLDDFQNKQGIESSDDAFLSKIYENVSNFNVPRKLHDIEHKFSKEEPSLILHIHKFHFRFEQQDGAFTYNGPVKSILQYIRMELIPPDCLEVFRNSDVKFYDGCLTVRIIDHRQSPSADQTVQPQPGSTNQQQQNNTNPINNQPEDTKPNTNSPPVYHTVLRPTPETLWQDLCLLSESFANSLSDEAVLTLESNILLASEAPLFLTPAKSKAEMIQFMNQLADSAPPCTRKKPQGSAQLADEEAERLEKENLLLLMDDQRKRDFQPTFQRLQFIENVRRKRAILQQRQMQMQQQQKAQQQQSPKAQQPPAHLVQSAPVQRKTTPKIQRLPPSSIQIPPPKPMQKFPANAASSESPPNATGNFLPSGPVPANEPMLKRESVDLIKIRQLAILFQQRASQLKARGATREQITEILNRQAIAAGTDLATVMTVARNLHFQQLQMRQQQQQQQMKAER
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).
What are the official names of this protein?
SAGA complex subunit spt20.
What is the protein family that this protein belongs to?
Belongs to the SPT20 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.