PharMolix/UniProtQA huggingface dataset:
Protein: IF2_MESHJ
Sequence: MKKSQKRISNVSEIKAQLKTVETKVHNGVFLFSGIMTIAELAQKINVSVNQIITYFFHQAKMYNLNHSLSEDEIAEICLEFGLDFKKEVQIDASNFMEEVSILDQDKDLSPRPPIITVMGHVDHGKTTLLDYIRKTNIAKNEKGGITQHTGAYQVVFQGHIINFIDTPGHEAFTQMRARGAKVTDIIVLVVAADDGVMPQTKEAINHAAAANVPIIVFVNKMDKPNKDVDRIKNELSALNIVTEEWGGSNIFVYGSALTGQGIDTLFSSILLLAEILELKANKNRYPIGTVIEAKLHHNKGTIATLMVQNGTLMVRDFIVAGYQYGRIRSLENTNGQPIKFAPPGTPVIVTGLNYVPEAGDKFFGFHEEKFAKQLALERKQSEKISKTKVQTKQQTKEKTLNIIIKADVAGIAQALHSTIEKLASKQVHIHILHSGVGIVNKADILLAQTSNSIIYAFNLQIPAAIKAQAKQAQVEIREHTIIYKIVDEIKKQVRGMREIRYELQQIGTAKIIAKFWFSKVGSIAGCSVLSGKFVENCKIELWRNSKLIHSGKIESLQRDKNPVKEVQVGNEFGTHIYKFNDIEIGDELKAFLDVEIEE
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAL1_CAEBR
Sequence: MSVDVKSEFSENDSSSSSSSPTNVNNVAWPNYQMMPFMNAQPLRDKMLQPSFDPQLYGRWPQMGEAGFYGHSDIYSTFALPQLSTNGQILPTAEVVEVKPPLSNGSSSSDSGMYPSPNDLTPFPSTSSGIGASSSSSDLQAAAAAAANYQMRAATCYQQSVWPFMDYQQPFPWKMPLGSAGKERRASSDTKSLPTGPGTNNVRVRTADKYRMVYSDYQRLELEKEFHTSAFITSDRKSQLSTMLSLTERQIKIWFQNRRAKDRRDKQKIRL
What is the function of this protein?
Transcriptional activator.  Interacts with promoter regions for tbx-8. 9, tbx-9, elt-1, hnd-1, scrt-1, and vab-7 genes.  Binds the sequence ATTTATGAC.  Binds to the enhancer region of the hlh-1 gene promoter during embryonic body wall muscle development.  Activates the gene for mab-5 in embryo development.  Necessary for vab-7 expression in C blastomeres in the posterior of embryos.  Required for posterior V6 neuroectoblast cell fate specification during postembryonic neurogenesis (patterning) which generates the characteristic ray lineage during male tail development.  Binds to ced-3 promoter and activated expression which is crucial for tail-spike cell death.  Has a role in E cell specification in endoderm development and body wall muscle development (By similarity).
What are the official names of this protein?
Homeobox protein pal-1, Posterior alae in males protein 1.
What is the protein family that this protein belongs to?
Belongs to the Caudal homeobox family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Chromosome. Note=Localized to condensed chromosomes.
Protein: SSRP_LISMF
Sequence: MPKGDGKLVAQNKKARHDYAIEETFEAGIVLQGTEIKSVRNARVNLKDSYARIDKGEIFLHNMHISPYEQGNRYNHDPLRTRKLLLHKKQISRLIGETKESGYSIVPLKMYIKDGYAKVLIGVARGKKKYDKRQDLKQKEAKRDIERAFKERQQ
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: NMS_RAT
Sequence: MKHPFPQFPPILVIYCFCMLQIPSSGASPPLAGPPDGLDAVDPERLAHFLNQRETCSNQPKESRDVYKRFLFHYSRAWKSTHPVNSEFAPVHPLMRLAAKLPSRRMKRLPRLLHTDSRMATIDFPKKDPTTSLGRPFFLFRPRNGRYTDKVQ
What is the function of this protein?
Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions.  Stimulates the contraction of rectum and elevation of blood pressure.
What are the official names of this protein?
Neuromedin-S.
What is the protein family that this protein belongs to?
Belongs to the NmU family.
What are the subcellular locations of this protein?
Secreted.
Protein: HISZ_NEIG1
Sequence: MQTWQLPEHIADVLPTNARQLESAREQLLALFRVHGYELVQPPLMEYAHSLLTHIDAGLSLKTILVTDRLSGRQLGIRADITPQVARIDAHLLSANQGINRLCYAGPVLHAQPDGLPNMREPLQAGAEMYGFADIRGDIELIDLMLKSMKIADMGKVLLSLGHIGIFRALSDAAHLDAGQSAALLALMQDKDTGSVEAQVKAWKLDGMWAKAFSLLPRLYGGREVLSDARGRLPDLSAVGGALDELQAVCDAFPDNEIHIDLSELRVDNYHTGLLYAAYAADFHDAVARGGRYDGLGGYFGRARPATGFSFDLRSFIGRLPAVERQPAVLVDAEDAEAAREAVEALREQGQCVVIDYGIGHNVSEELAGRLKKTDGVWQVVKR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTN14_HUMAN
Sequence: MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPVHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSVNSLNCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGILHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTVPYGPQGVYSNKLVSPSDQRNPKNNVVPSKPGASAISHTVSTPELANMQLQGSHNYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGTVNKRHSLEVMNSMVRGMEAMTLKSLHLPMARRNTLREQGPPEEGSGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEAPESVPQIPMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQASLPPAMARARVLRHGPAKAISMSRTDPPAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLAALNGLSVARVSGREENRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI
What is the function of this protein?
Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition.  Mediates beta-catenin dephosphorylation at adhesion junctions.  Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner.  May function as a tumor suppressor.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 14, Protein-tyrosine phosphatase pez.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Translocation into the nucleus is associated with induction of cell proliferation. Partially colocalized with actin filaments at the plasma membrane.
Protein: YL688_MIMIV
Sequence: MYLFYQLILEIFQIMSCQNYQSYGCGTYPCVTYGNCYTTCASPCLPYPTNCVQVCTSSQPCPSPCPIPVPCPVTIVEYITTAPTATTIESSPTGMALTPIPVGSTSIPSGTVTVITGYAATPVRSIGGITLNSALGQFTVPLAGSYLITGYIGFSYNAVGIREVYVYKVDGATSVITLISTDSRNTTATNPTYISYSAMDYFNAGDRIFIAAAQNSGSTITTTADNRIAITRMNRQ
What are the official names of this protein?
Uncharacterized protein L688.
What are the subcellular locations of this protein?
Virion.
Protein: MRNCL_FUSNN
Sequence: MDNVDFSKDIRDYSGLELAFLGDAIWELEIRKYYLQFGYNIPTLNKYVKAKVNAKYQSLIYKKIINDLDEEFKVIGKRAKNSNIKTFPRSCTVMEYKEATALEAIIGAMYLLKKEEEIKKIINIVIKGE
What is the function of this protein?
Might be a ribonuclease involved in RNA processing.
What are the official names of this protein?
Mini-ribonuclease 3-like protein.
What is the protein family that this protein belongs to?
Belongs to the MrnC RNase family.
Protein: RL30_STRS2
Sequence: MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNPAILGMVNAISHLVTVEEVK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: CS3HE_THETK
Sequence: MVGRRLDTLVRELSLAWCRSKGEPSCAVREDLLAEQAKAAEVIERSDGVILLKAPTGFGKTEIWTAPFFAQWLRGEWFAPRMYVVEPMHALLRQMKRRMEVYAQAVQGLGLPRLNVAEDHGEVAKPLFLYGGHIVLTTVDSLAYGYLARRVQRWREEGVERGRYSMPAGLLASAYIVLDEAHLIQDEAYLGPRVLGKIVCDLASAGAKVVISTATVPETFLKHIPCLGGRLTLGSGTVRRNVKVERRKGVLKAEEIECGKPTIVIVNTIERARRIYKQVRCGKKAVVHSLMRREDKERQLSKVLADGKVAEDAVLIGTQALEVGLDFSNLRALYTETAPVDALIQRIGRVGRDGDKAEAYIYEAEGDAPYPQTLMRATREALEKELLGGAALTSWEDAQRAVDKVYNEKAVEELMTRGLAWYGQALGYLQELSLFSYPPRGEVRIRPSNYITLVIADVKQDGDKGRYITEDDVERGAMKMSYTSRDDPRINALLQKVSTAYTVRGVATAKDETRYYLSELRRSWDGVEVVVVDRRDVEELYDEAGLDVAQLSGGGQKRKGRGRRRR
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity.  Probably unwinds dsDNA templates, thus providing substrates for CRISPR-associated endonuclease Cas3-HD.  Unwinding is strongly increased in the presence of ATP, implying the helicase uses ATP to unwind substrate (By similarity).
What are the official names of this protein?
CRISPR-associated helicase Cas3.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated helicase Cas3 family.
Protein: SERC_SALGL
Sequence: MAQVFNFSSGPAMLPAEVLKLAQQELRDWHGLGTSVMEISHRGKEFIQVAEEAEQDFRDLLNIPSNYKVLFCHGGGRGQFAGVPLNLLGDKTTADYVDAGYWAASAIKEAKKYCAPQIIDAKITVDGKRAVKPMREWQLSDNAAYLHYCPNETIDGIAIDETPDFGPEVVVTADFSSTILSAPLDVSRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHESCPSILDYTVLNDNDSMFNTPPTFAWYLSGLVFKWLKAQGGVAAMHKINQQKAELLYGVIDNSDFYRNDVAQANRSRMNVPFQLADNALDKVFLEESFAAGLHALKGHRVVGGMRASIYNAMPIEGVKALTDFMIDFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_MYCA1
Sequence: MAVGISPGELRELTDDELTERLRESKEELFNLRFQMATGQLTNNRRLRTVRQEIARVYTVLRERELGLASGPDGKES
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: AIM3_YEAS2
Sequence: MGFWENNKDSITSGLKSAGKYGYQGTKYVAKTGYKASKKHYNNSKARRERKSGKKNSSDEEYDSEDEMEYERKPTDIRSLKDPKSFPPPPLKPGQKTYTGQQQQQMPNGQASYAFQGAYQGQPGAGSMEQSQYAQPQYNQYPQQQLQQGVMPQQQQLQQGVVPQQPPIYGEQVPPYGSNSNATSYQSLPQQNQPQNAIPSQVSLNSASQQSTGFVSQNLQYGTQSSNPAPSPSFQNGLQCHQQPQYVSHGSTNLGQSQFPSGQQQQPTTQFGQQVLPSPAQPQQQQQGQPLPPPRGQVILPAPGEPLSNGFGQQQQQQQQQQQPLNQNNALLPQMNVEGVSGMAAVQPVYGQAMSSTTNMQDSNPSYGASPMQGQPPVGGQPPVPVRMQPQPPQPMQQGNIYPIEPSLDSTGSTPHFEVTPFDPDAPAPKPKIDIPTVDVSSLPPPPTHRDRGAVVHQEPAPSGKIQPNTTSSAASLPAKHSRTTTADNERNSGNKENDESTSKSSILGHYDVDVNIMPPPKPFRHGLDSVPSEHTRKNAPERAVPILPPRNNVEPPPPPSRGNFERTESVLSTNAANVQEDPISNFLPPPKPFRHTETKQNQNSKASPVEMKGEVLPGHPSEEDRNVEPSLVPQSKPQSQSQFRRAHMETQPIQNFQPPPKPFRRSQSSNSSDSSYTIDGPEANHGRGRGRIAKHHDGDEYNPKSENSTENGRLGDAPNSFIRKRAPTPPAPSRSEKLHEGTITSEVDSSKDANKYEKSIPPVTSSIQAQQSTKKAPPPVVKPKPRNFSLKANEYPKELTREATGQDEVLNSITNELSHIKLRKTNVNLEKLGGSKKVKDSSPVPSDLDEKYVSASGSITPPRPPPSRSSPKKVPPVVPKNNDNLKKKPPVVPKKKPLLKSLEPRPIEMERAYSGDISAADDNLNPFERYKRNVVPQEDDRLHKLK
What are the official names of this protein?
Altered inheritance of mitochondria protein 3.
What is the protein family that this protein belongs to?
Belongs to the AIM3 family.
What are the subcellular locations of this protein?
Membrane raft; Peripheral membrane protein. Note=Localizes within detergent-insoluble glycolipid-enriched membranes.
Protein: MUG98_SCHPO
Sequence: MSIPVMQLKHELALKAREEYLRKELPLKVRANTSRMNPGAKTWIPQINHRKSRNHYNRKETCQFPPLYNVEAKINHSYSAFYRPFTKRENGLWYANPYYMQHGPNGNYHHVYY
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 98 protein, mitochondrial.
Protein: Y1907_GEOSW
Sequence: MRVLAITGYKPYELNIFSNNHPAVSYIQLAIRRRLLSLLEEGLEWIVISGQLGVELWAAEIAYDLREEYPQLQVAILTPFLNQEERWNEMNREYYEWIVSQADFVDSITKRPYESPAQFRWKNEWIVRKSDGLLIVYDEEKEGTPKYMLEVAKRKENYAIFPITFSDLQAIIEEAQINETQIDNRFDF
What are the official names of this protein?
UPF0398 protein GWCH70_1907.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: GLPB_ECO81
Sequence: MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYTLLGPQRVLDLACQAQALIAESGAQLQGSVELAHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLKVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWHWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERDGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDEALRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: GPMI_MALP2
Sequence: MKKGPVLLAVLDGYGFSKDTKGNAILNAKTPFMDNLVKEYDHCYIEASGEYVGLPDGQIGNSEVGHLTIGAGRIVYTGLSLINQDIKTKKFDSNKTLLEAINHAKKNNSNIHIMGLLSPGGVHSNEQHIFEMIRIVSENGLKPVIHVFGDGRDVAPQSIISSLERLNDVLKKYPGTIATISGRFYSMDRDKRWERTKQAYDNLLGISNNYFDNPIDYVNKQYSENIFDEFLVPARINDSNVVIKDNDAVIHANFRPDRARQISHLFCGSTVYEEKNDHPLKNLYYAIMMTYEGITPTSILFPTVVVKNTFGEVVANSGLTQLRIAETEKYAHVTFFFDGGVEVDLKNESKILVDSKKVKTYDEVPAMSAVEITDKLIENLDKFDVIVLNFANADMVGHTGKYNEAVLAIEALDSQLARIDQKIKELNGTMFITADHGNAEVMLDDDNNPVTKHTTNPVIFISNNKDVKFNKPGSLGNVAPTILDFMGLEIPADMDKKSLLKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: YL537_MIMIV
Sequence: MAEDKIEAYNKSITRTKYFKMDDAINSPICSKTVFIIANERITKENRIGRYYTVFPSFKKFLKKRDSYPQCHEIIIDHINNKTNIAGRLVFDFDIKITDSSILKDTGLIDKNDNQPIMFNSKTLSITKIPLNFKQQIENTIIETIDQYFHDIDKTILEFIWSTSQNPNKFSKHLTVKNLYFDDWITMSKLFYKLFCKVWDNQYYWISSKDLVDSQIVRNKGSLRMVGSTKINGYPLVFDNKNHTLPDSLIRIYFRNHREKEQLVTRNNINKDIINQFLESNDDIEHHRSIDIIDRHFTKIRNPSYDPIIYQKAFEIYDAIHPNIFKMGKVNGKYLTLIRLKPHTCFLSNKFHEQENAYLYISMSDTTYKISFGCYRFCSKKKMEYLGSLIQGNLMKNSPYIDDTDGTTKKHDFNINIKFLSDSDDESINAPNNIKSLESIKSSKSKKQLKSSKSKKPIKHTKTKNIYVET
What are the official names of this protein?
Uncharacterized protein L537.
Protein: RL21_BACCN
Sequence: MYAIIETGGKQIKVEAGQEIYIEKLDVEAGETVTFDKVLFVGGENVKVGSPVVEGATVTAKVEKHGRAKKIIVFKYKAKKNNRKKQGHRQPYTKLVVEAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RECF_LEUMM
Sequence: MELESLKLDHYRNYSDLTLEFSSGVNVFLGENAQGKTNLLESIYVLALARSHRTSSDKDLVQWQAKEATISGRVKRSISETPLSLHFSNKGKKARVNHLEQSKLSHYIGQLNVILFAPEDLELVKGAPSVRRRFIDMEFGQMNPLYLYNTTQYKRILKERNAYLKRLQLKQTTDTVFLDVLSEQLVDVGSQILIARQEFLNKLELAAQPIHAEISDQREALKLRYMSSVDFASDASLEEVKSVFADALSRQRSREIMQGSTMVGPHRDELQFDVNGNNVAIFGSQGQQRTTALAIKLAEIDLMQQETGEYPVLLLDDVLSELDASRQTHLLLAIQDKVQTFITAPTLSDIARQLIRKPRVFHVKQGVITLENDT
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDE10_CAEEL
Sequence: MSNHRSNFRDYQREGIRANNAGTSGDAVRQNGNPISVAKHVDGKKSVYMLFLRQIGQKKFLTEQGHRYNQNDQADKDIMTRYYHGMCPDLKQKFEREVAEHNGNRGLVIKTKHQRAQRNREMRHRNPDEFQQLRRAHLETLSQTPSVIALPRDINHVLHITEDLDAFCLANRKKAKRIMTSYIAQRSDDPGNPLLCEDYTMQIVSVFPVAYAFKPSINKLSSYPAEISVTTFNLKNGIIQNESRFVKFDAAWFYPDADDIGHEELSRKAMADELGISPNGPADGCEPYEVFEWLQHLLKQHPKSPILCDRAQFNFVYYGIKTLATYTGINAITFFQEVIIPSILSIQDFTSVILEKAPTDVPRVWRDVDICNQFQYHFLIPRTELNLFCSFHENKPSPTKYNCVKAHNARLLDNFFTVIKGNRLQGFVISPPVHEICIQDGSDTSLPQTILARTISRNDAEVYAARQRDTDEQYDVHQEGPSNHDQYEFASEPLDFEEDSDEENYNEQLDVPYSYNDHFISSSSVREPEHPSARSRDVAPNVQQESVVVPAPRRLSPQRAPRPSQNSPNAYSERKSFSAFPSEDPSEDYETPIISHIMNRNEADQYFNILDSVKPGQKYKIIKFDDF
What is the function of this protein?
In complex with rde-11, required in the endogenous and exogenous siRNA pathway for biogenesis and accumulation of secondary small interfering RNA (siRNA) intermediates, such as 22G-siRNAs derived from ergo-1 targets.
What are the official names of this protein?
RNA interference defective protein 10.
What is the protein family that this protein belongs to?
Belongs to the maelstrom family.
Protein: CH60_GARVA
Sequence: MAKIIAYEEDARQGMLAGLDRLANTVKVTLGPKGRNVVLDKSYGAPTITNDGVSIAKEIDLEDPYERIGAELVKEVAKKTDDVAGDGTTTATVLAQSLVHEGLKNVVAGSNPIALRRGIEKASEAIVKELLASAKDVETKDQIAATATISAADPEVGEKIAEALDKVGQDGVVTVEDNNKFGLDLDFTEGMRFDKGYISPYFVTNAEDQTAVLEDPYILLTSGKVSSQQDIVHVAELVMKSGKPLLIIAEDVDGEALPTLVLNKIRGTFNTVAVKAPGFGDRRKAMLQDMAILTGAQVVSDDLGLKLDSIDASVFGHAAKVIVSKDETTIVSGAGSKEDVEARVAQIRAEIENTDSDYDREKLQERLAKLAGGVAVIKVGAATEVEAKERKHRIEDAVRNAKAAIEEGLLPGGGVALVQAAAKVEKSADIVALSGEEATGAAIVFRAVEAPIKQIAQNSGVSGDVVLNKVRELPEGEGFNAATNTYEDLLAAGVTDPVKVTRSALQNAASIAGLFLTTEAVVANKPEKPAAAPQAGAEMGY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_PSEP1
Sequence: MSEPRQILVTSALPYANGSIHLGHMLEYIQTDMWVRFQKLRGNQCIYVCADDAHGSAIMLRAEKEGITPEQLIANVQAEHSSDFADFLVDFDNFHSTHSEENRELSSLIYSRLREAGHIATRSVTQYFDPEKGMFLADRFIKGTCPKCAAEDQYGDNCEKCGATYAPTELKNPKSAISGATPVLRDSQHFFFKLPDFQAMLQQWTRSGTLQDAVANKLAEWLDSGLQEWDISRDAPYFGFEIPGEPGKYFYVWLDAPIGYMASFKNLCARRPELDFDAFWNEGSKAELYHFIGKDIVNFHALFWPAMLEGAGFRKPTAVNVHGYLTVNGAKMSKSRGTFIKARTYLDHLQPEYLRYYYAAKLGRGVDDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNEGVMVGGDAAPELTEAFLAAAPSIAEAYEARDFGRAMREIMALADRANAWIADKAPWSLAKQEGKQDEVQAICAQGINLFRQLVIFLKPVLPVLAADAEAFLNVAPLTWNDHLTRLENHTLNPFKALMSRIEPAKVEAMVAASKEDLLAAEAKAPAGNGELAKDPLSAEIEFDTFAAVDLRVALIVKAEAVAGADKLLQLTLDIGDERRNVFSGIKSAYPDPSKLEGRLTMMVANLKPRKMRFGVSEGMVMAAGPGGEEIYLLSPDSGAKPGQRIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASZ1_HORSE
Sequence: MAAARFRGLAVAGGGESSESEDDGWEIGYLDRAAQKLKEPLPIEEKNETFKRALTAGDVALVEELLDSGISVDSSFRYGWTPLMYAASVSNVDLVRVLLDRGAKASFDKDKQTILITACSARGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHPQVVALLVAHGAEVNTQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKDGKTPSEIAKRNKHLEIFNFLSLTLNPLEGKLQQLTKEETICKLLTTKSDKEKDHIFSSYTAFGDLEIFLHGLGLEHMTDLLKERDITLRHLLTMRKDEFTKNGITNKDQQKILAALKELEVEEIKFGELPEMAKLEISGDEFLNFLLKLNKQCGHLITAVQNIINELPVNSHKIVLEWASPRNFTSVCEELVGKVEDLSEEVCKLKDLIQKLQNERENDPAHIPLMEEVSTWNSRILKRTAITVCGFGFLLFICKLTFQRQ
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: MOAA_AGRFC
Sequence: MNSFSGSLEKAKTLTENNAPMVDPFGRAITYLRVSVTDRCDFRCTYCMSEHMTFLPKKDLLTLEELDRLCSVFITRGVRKLRLTGGEPLVRKNIMSLVRNLGRHVQSGTLDELTLTTNGSQLAKFAAELADCGVRRINVSLDTLDAQKFRQITRWGDIDRVMEGFDAAQAAGIKVKLNAVALKDFNDAEMPELMRFAHGRGMDLTVIETMPMGEIEEDRTDRYLPLSQLRADLERNFTLVDSDYQTGGPARYVTVKETGGRLGFITPMTHNFCESCNRVRLTCTGTLYMCLGQDDAADLRTALRASDSDAYLSAAIDEALLRKPKGHDFIIDRTHNRPAVSRHMSVTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.