PharMolix/UniProtQA huggingface dataset:
Protein: RHAB_MANSM
Sequence: MTILNIAAVDLGASSGRVMLASYSTENHKISLEEIHRFKNQFVSQNGHECWDLAYLENEIVNGLRKISNSGRTLHSIGIDTWGVDYVLLDQNGEVVGPTYAYRDHRTDGVMQKVQAELGKEVIYRKTGIQFLTFNTLYQLKAMTDENPAWLSQVKDFVMIPDYLNYRLTGVINREYTNATTTQLVNVNIDSWDTALLDYLGLPASWFGRIRHPGHQVGLWENRVPVMSVASHDTASAVISAPLSDENAAYLCSGTWSLMGLDTTTPCTDECAMNANITNEGGIDGHYRVLKNIMGLWLFNRLCTERDVTDIPALVKQAEAELPFQSLINPNAECFLNPSSMVEAIQQYCREHNQVIPKTTAQLARCIFDSLAMLYRKVALELAGLQGKPISALHIVGGGSQNAFLNQLCADLCGIDVFAGPVEASVLGNVGCQLMALDQIHNAAEFRQLVVKNFPLKQFKKRPHFMPASDFEEKWCEFCALN
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: PANB_OLEA2
Sequence: MSTHAETRAITAADIRAAKNTRRLAMLTAYDYPTASIADEGGMDMLLVGDSLAMVVLGHEDTLSVTLDEMIHHCRAVTRGASRALVVGDLPFMTYEQGPDQAMHSAARLFREGGVRAVKLEGGKEVAPQVEALVKAGIPVMGHIGLTPQRVAALGGFKVQGRSAAAARSLAEDARILEDAGCFALVLEAIPAPVAAHITRTSGIPTIGIGAGAQCDGQVLVVHDMLGLFDRFTPKFVKRYAELRGHAVKAVQQYGDEVRQGEFPAAQHSFGMPEDEQRRWEENVSGADD
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCF1_ZYGRC
Sequence: MSGLPSSFDSKEASVDELPFLEKVKFHCKQQPLVPLGTLLTTGAVALAAQNVRTGNKKKAQVWFRWRVGLQAATLVALVAGSFIYGSSLKEKKSEEEKMREKAKMRELLWIQELERRDQETQYRRKRAELARQKMQENEAAVSRLQKELKDLESHIKNEK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SYS_NATTJ
Sequence: MLDVKYIRNNPDEARKACVQKGEDDHVDEILKYDEQRRKILTDLEVLKNKRNTVSKEIGQLKKEGHDAQDKIAEMKEVSDKVKEMDDELKKVDEQLNYHLLCIPNIPNPDVPVGDDDEDNQVVKQVGEPVKKDYFKPHWEVAENLNLLDFKRAGKVTGTRFVNYVGDAARLERALIDFMIDVHVTEHGYVEMMPPFIANRDSMTGTGQLPKFEDDMYKLEDMEYFLIPTAEVTLTNLYRDEILPGDFLPRYLVAFTPCFRKEAGAHGRDTRGLIRQHQFNKVEMVKFVEPEKSYQELDSLVANAERVLQLLELPYQISLMCTGDLGFAAAKKYDLEVWLPSYDTYREISSCSNFEDFQARRANIRYRPEEGEKARFVHTLNGSGLAVGRTLAAILENYQNPDGTVTIPEVLKPYFNGRDVIS
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP5_MOUSE
Sequence: MHWTVFLLRGIVGFLWSGWVQVGYAKGGLGDNHVHSSFIYRRLRNHERREIQREILSILGLPHRPRPFSPGKQASSAPLFMLDLYNAMASEDNPEEYLVRVSLAGEAKETRKGYPASPNGYAHRLHLPPRTPLTTQSPPLASLHDTNFLNDADMVMSFVNLVERDKDFSHQRRHYKEFRFDLTQIPHGEAVTAAEFRIYKDKGNHRFENETIKISIYQIIKEYTNRDADLFLLDTRKTQALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETGDGRSINVKSAGLVGRHGPQSKQPFMVAFFKASEVLLRSVRAASKRKNQNRNKSNSHQDPSRMPSAGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGCH
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cartilage and bone formation or neurogenesis (PubMed:7958439, PubMed:29321139).  Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2.  In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.  Can also signal through non-canonical pathway such as MAPK p38 signaling cascade to promote chondrogenic differentiation (By similarity).
What are the official names of this protein?
Bone morphogenetic protein 5, BMP-5.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: YNFA_SALNS
Sequence: MLKTTLLFFVTALCEIIGCFLPWLWLKRGASVWWLLPAAASLALFVWLLTLHPAASGRVYAAYGGVYVCTALLWLRVVDGVRLTVYDWCGALIALCGMLIIVVGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UXAB_BACTN
Sequence: MKALNKETAPKVQRPERIIQFGEGNFLRAFVDWIIYNMNQKTDFNSSVVVVQPIDKGMVDMLNAQDDLYHVNLQGLDKGEVVNSLTMIDVISRALNPYTQNDEFMKLAEQPEMRFVISNTTEAGIAFDPTCKLEDAPASSYPGKLTQLLYHRFKTFNGDKTKGLIIFPCELIFLNGHKLKETIYQYIDLWNLGNEFKTWFEEACGVYATLVDRIVPGFPRKDIAAIKEKIQYDDNLVVQAEIFHLWVIEAPQEVAKEFPADKAGLNVLFVPSEAPYHERKVTLLNGPHTVLSPVAYLSGVNIVRDACQHEVIGKYIHKVMFDELMETLNLPKEELKKFAEDVLERFNNPFVDHAVTSIMLNSFPKYETRDLPGLKTYLERKGELPKGLVLGLAAIITYYKGGVRADGAEIVPNDAPEIMNLLKELWATGCTKKVTEGVLAAEFIWGEDLNKIPGLAAAVKADLDSIQEKGMLETVKGIL
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: HSLO_CROS8
Sequence: MAQHDQLHRYLFENYAVRGELVTVSETWKQILENHDYPMPVKTLLGELLVATSLLTATLKFAGDITVQLQGDGPMTLAVINGNNRQQMRGVARVQGDVPADADLKTLVGNGYLVITITPEEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGEAQGQPAAGGMLLQVLPAQDAQTDDFNHLATLTETIKADELFTLPANDVLWRLYHEEEVTVYDPQAVEFKCTCSRERCADALRTLPDEEVAQILEEDGEVDMHCDYCGTHYVFDAMDIAGIRKNASPADPQVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBC12_MOUSE
Sequence: MMGPEDAGACSGRNAELLPVPGPMGQDGKTVPATSGFSGGAVAAEPPEEAGEEEAPPPRQLLQRYLAAAAGPLKPGLGGAEAEEAAAAAVPAARGSGMTNGDSGFLLRQDRRGPEEARRRRTCGRPCLLEPADEGVDGAGGLDDWAAPLEDPLRSCCLAAGDTDDPDPAAATPAGRAVESAEPSLGLPDARFGSRNTFEVSRRQSAGDLLPSAGPSAPLPAAEQGPGGTTARARRSGGFADFFARNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTCKAAPQSSRRKSFALEPLSTTALILEDRPPNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEESIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSESSSENDTEGLSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVAKDIKEGDKNTSPALKS
What is the function of this protein?
RAB11A-binding protein that plays a role in neurite outgrowth.
What are the official names of this protein?
TBC1 domain family member 12.
What are the subcellular locations of this protein?
Endosome.
Protein: KCNH2_HUMAN
Sequence: MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
What is the function of this protein?
Has no channel activity by itself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.
What are the official names of this protein?
Potassium voltage-gated channel subfamily H member 2, Eag homolog, Ether-a-go-go-related gene potassium channel 1, ERG-1, Eag-related protein 1, Ether-a-go-go-related protein 1, H-ERG, hERG-1, hERG1, Voltage-gated potassium channel subunit Kv11.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPF_BACFN
Sequence: MSLLLPDSGLIFWMLLSFGIVFAVLAKYGFPVIIKMVEGRKTYIDESLEVAREANAQLSRLKEEGEAIVAAANKEQGRIMKEAMQEREKIIYEARKQAEIAAQKELDEVKRQIQIEKDEAIRDIRRQVALLSVDIAEKVIRKNLDDKQEQMGMIDRMLDEVLTKN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PHLA2_MOUSE
Sequence: MASKIVMSSKTVKTSDEILCEGELEKRSDSLFQVWKKKRCVLTADRLRLFSGKTSPAKELFFHSILKVDCVEHTSKYVYFTIVTNYYKEIDFRCTVESCWNAAITMALIDFQNRRALQDFPRYRYQRSESEMPSEPGEQSALGP
What is the function of this protein?
Plays a role in regulating placenta growth.  May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.
What are the official names of this protein?
Pleckstrin homology-like domain family A member 2, Imprinted in placenta and liver protein, Protein 50C15.
What is the protein family that this protein belongs to?
Belongs to the PHLDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: PUR7_LEPIC
Sequence: MNPSYKGKVRDIYDLGDKLILSSSDRISAFDVVFPQLVPDKGKVLNRISVSWFEFFKDVPNHILETDVKYFPIPFQNHPDLEGRSVLVKKCKRIDYECVVRGYISGSGWKEYKNDGTLAGIKLPSGFKESQKLPEPVFTPAVKNDQGHDENISEKEMENRIGKELFNILKEKSISIFLRASEVVDKAGIILCDTKFEFGILDGQVILIDELLTPDSSRYWSTDTYSVGISPPSLDKQILRNYLETTSWNKMPPAPNLPAELIQELREKYQKIEDLILSCTSQKSK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PRIB_PHOLL
Sequence: MTTNRLVLSGTVCKVPIRKVSPAGIPHCQFVLEHRSQQQEAGLSRQAWCRMPVIASGQLLQVLTHSITVGSRLTVSGFISCHQGRNGLNKLVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: KATG_CLOBB
Sequence: MTENKCPVTGKMGKATAGSGTTNKDWWPNQLNLNILHQNSQLSNPMSKDFNYAEEFKKLDFQALKVDLYMLMTDSQIWWPADYGNYGPLFIRMAWHSAGTYRVGDGRGGGSLGLQRFAPLNSWPDNINLDKARRLLWPIKKKYGNKISWADLLILTGNCALESMGLKTLGFGGGRVDVWEPQEDIYWGSEKEWLGDEREKGDKELENPLAAVQMGLIYVNPEGPNGNPDPLGSAHDVRETFARMAMNDEETVALIAGGHTFGKCHGAASPSYVGPAPEAAPIEEQGLGWKNTYGSGNGDDTIGSGLEGAWKANPTKWTMGYLKTLFKYDWELVKSPAGAYQWLAKNVDEEDMVIDAEDSTKKHRPMMTTADLGLRYDPIYEPIARNYLKNPEKFAHDFASAWFKLTHRDMGPISRYLGPEVPKESFIWQDPIPLVKHKLITKKDITHIKKKILDSGLSISDLVATAWASASTFRGSDKRGGANGGRIRLEPQKNWEVNEPKKLNNVLNTLKQIKENFNSSHSKDKKVSLADIIILGGCVGIEQAAKRAGYNINVPFIPGRTDAIQEQTDVKSFAVLEPKEDGFRNYLKTKYVVKPEDMLIDRAQLLTLTAPEMTVLIGGMRVLNCNYNKSKDGVFTNRPECLTNDFFVNLLDMNTVWKPKSEDKDRFEGFDRETGELKWTATRVDLIFGSNSQLRAIAEVYACDDNKEKFIQDFIFAWNKIMNADRFEIK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: ACP_KLEP7
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y225_MYCGE
Sequence: MGQINRKFSEKQFLLFVVNYIAGFGFIATAISLFRLGPFSWLIFLLVSLVSLIVTLSFARLSSIDSQNYGGPYLWAKKAVDKEKIAGRMFSFFTGWNNFIIGPLSAATAPLFILNSFSGIDGIRGNLVNTWILIAIGFSFYVLLAFISTKGTSLNKKLIALFASVKWIVILSALIVAIYVIARDGNGYSQNNNLESGFFGRREISFAQIATVFITFFYSYAGVEDISVMTPDVKTNNFRKILIVSFIAVFLFYFIGIIILNGLQNIAQRGGEANSIGNVADIFKKAAGLGTLIFYGVGALFNNVSTRLSTIIANSRKILPLAYDNYLPSFFYKQNKKGEFQNAIWFTFGTTLIAMTLLVFIPLVASNFDFDNATEYAASVGSAATLLQYIFVFFIIFKFIYKKEPLYQKKWVKTTEELLFCLGTIVIVLMLLVYLFPVIDGFSKWETKHTLTIVLYGVLSLIGLVLFLLQEYKHKNKQNANKQTTQTTV
What are the official names of this protein?
Uncharacterized protein MG225.
What is the protein family that this protein belongs to?
To M.genitalium MG226.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: A2012_HUMAN
Sequence: MKEMYENAEDKVNNSTGKWSCVEERICHLQHENPCIEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMNECDHLKESLFQYEREKAERVVVVRQLQQEAADSLKKLTMLESPLEGISHYHINLDETQVPKKKLFQVESQFDDLMVEKEAVSSKCVNLAKENQVFQQKLLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAQYKKQLEQLNKDIIQLH
What are the official names of this protein?
Putative ankyrin repeat domain-containing protein 20A12 pseudogene.
Protein: PLPP3_MOUSE
Sequence: MQSYKYDKAIVPESKNGGSPALNNNPRKGGSKRVLLICLDLFCLFMAALPFLIIETSTIKPYRRGFYCNDESIKYPLKVSETINDAVLCAVGIVIAILAIITGEFYRIYYLKEKSRSTTQNPYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCDPDFSQINCSEGYIQNYRCRGEDSKVQEARKSFFSGHASFSMFTMLYLVLYLQARFTWRGARLLRPLLQFTLLMMAFYTGLSRVSDYKHHPSDVLAGFAQGALVACCIVFFVSDLFKTKTSLSLPAPAIRREILSPVDIIDRNNHHNMV
What is the function of this protein?
Independently of this phosphatase activity may also function in the Wnt signaling pathway and the stabilization of beta-catenin/CTNNB1, thereby regulating cell proliferation, migration and differentiation in angiogenesis or yet in tumor growth (PubMed:12925589, PubMed:27125875).  Also plays a role in integrin-mediated cell-cell adhesion in angiogenesis (PubMed:16099422).
What are the official names of this protein?
Phospholipid phosphatase 3, Lipid phosphate phosphohydrolase 3, PAP2-beta, Phosphatidate phosphohydrolase type 2b, Phosphatidic acid phosphatase 2b, PAP-2b, PAP2b.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
Protein: MIIP_HUMAN
Sequence: MVEAEELAQLRLLNLELLRQLWVGQDAVRRSVARAASESSLESSSSYNSETPSTPETSSTSLSTSCPRGRSSVWGPPDACRGDLRDVARSGVASLPPAKCQHQESLGRPRPHSAPSLGTSSLRDPEPSGRLGDPGPQEAQTPRSILAQQSKLSKPRVTFSEESAVPKRSWRLRPYLGYDWIAGSLDTSSSITSQPEAFFSKLQEFRETNKEECICSHPEPQLPGLRESSGSGVEEDHECVYCYRVNRRLFPVPVDPGTPCRLCRTPRDQQGPGTLAQPAHVRVSIPLSILEPPHRYHIHRRKSFDASDTLALPRHCLLGWDIFPPKSEKSSAPRNLDLWSSVSAEAQHQKLSGTSSPFHPASPMQMLPPTPTWSVPQVPRPHVPRQKP
What is the function of this protein?
Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1.  Exhibits opposing effects to IGFBP2 on cell invasion.
What are the official names of this protein?
Migration and invasion-inhibitory protein, IGFBP2-binding protein, Invasion-inhibitory protein 45, IIp45.
Protein: RS20_BRASB
Sequence: MANTTSAKKATRKIARRTIINKSRRTQMRGAVRSVEDAIKKGDREAALKAMANAEPQLMRAAQRNIIHKNNASRKVSRLTHQIAKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: 14332_ORYSJ
Sequence: MSAQAELSREENVYMAKLAEQAERYEEMVEFMEKVAKTVDSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEDRVTLIKDYRGKIETELTKICDGILKLLESHLVPSSTAPESKVFYLKMKGDYYRYLAEFKTGAERKDAAENTMVAYKAAQDIALAELPPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAISELDTLSEESYKDSTLIMQLLRDNLTLWTSDISEDTAEEIREAPKRDSSEGQ
What is the function of this protein?
Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.
What are the official names of this protein?
14-3-3-like protein GF14-B, G-box factor 14-3-3 homolog B.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LRPC_BACSU
Sequence: MKLDQIDLNIIEELKKDSRLSMRELGRKIKLSPPSVTERVRQLESFGIIKQYTLEVDQKKLGLPVSCIVEATVKNADYERFKSYIQTLPNIEFCYRIAGAACYMLKINAESLEAVEDFINKTSPYAQTVTHVIFSEIDTKNGRG
What is the function of this protein?
Transcriptional regulator with a possible role in regulation of amino acid metabolism.  Plays a role in the growth phase transition.
What are the official names of this protein?
HTH-type transcriptional regulator LrpC.
Protein: ARFRP_PONAB
Sequence: MYTLLSGLYKYMFQKDEYCILILGLDNAGKTTFLEQSKTRFNKNYKGMSLSKITTTVGLNIGTVDVGKARLMFWDLGGQEELQSLWDKYYAECHGVIYVIDSTDEERLAESKQAFEKVVTSEALCGVPVLVLANKQDVETCLSIPDIKTAFSDCTSKIGRRDCLTQACSALTGKGVREGIEWMVKCVVRNVHRPPRQRDIT
What is the function of this protein?
Trans-Golgi-associated GTPase that regulates protein sorting.  Controls the targeting of ARL1 and its effector to the trans-Golgi.  Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver.
What are the official names of this protein?
ADP-ribosylation factor-related protein 1, ARF-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus. Golgi apparatus, trans-Golgi network. Note=Located in the trans-Golgi in the GTP-bound active state.
Protein: Y1009_STAAC
Sequence: MRLYINEIKIKDDILYCYTEDSIKGLSEVGQMLVDSDNYAFAYTLDDGKAYAYLIFVQETWTMLHENMTKKIIINDELELTEFHQELTYILDNIKGNNNYGKEFVATVEETFDIE
What are the official names of this protein?
UPF0738 protein SACOL1009.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: BRK3_PHYSA
Sequence: VPPGFTPFR
What is the function of this protein?
May produce in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle.  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
[Val1,Thr6]-bradykinin.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: GRAPL_HUMAN
Sequence: MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNNRAQRGPCLGPKSHSRLG
What are the official names of this protein?
GRB2-related adapter protein-like.
What is the protein family that this protein belongs to?
Belongs to the GRB2/sem-5/DRK family.
Protein: SYL_BRUME
Sequence: MAAERYNPRVAEAHWQKVWEENRTFETDNSDSREKYYVLEMFPYPSGRIHMGHVRNYAMGDVVARYKRAKGFNVLHPMGWDAFGMPAENAAMQNKVHPKEWTYQNIATMKRQLKSMGLSLDWSREFATCDVEYYHRQQMLFIDLYEKGLVTRKTSKVNWDPVDNTVLANEQVVDGRGWRSGALVEQRELTQWFFKITDFSEELLAGLDTLDQWPEKVRLMQRNWIGKSEGLQVRFALAAGTAPAGFSEVEVYTTRPDTLFGAAFVAISADHPLAKKLSEGNAALSSFIEECHQQGTSLAALETAEKKGFDTGIKVKHPFDDNWELPVYVANFVLMEYGTGAVFGCPAHDQRDLDFANKYKLKVTPVVLPKGEDAASFSIGETAYTDDGVMINSRFLDGMTPEAAFNEVASRLEKTDLVGRPQAVRKVQFRLRDWGISRQRYWGCPIPMIHCESCGVNPVPRADLPVKLPDDVEFDRPGNPLDRHATWRHVKCPKCGGDARRETDTMDTFVDSSWYYTRFTAPWENEPTDRKAADHWLPVDQYIGGIEHAILHLLYSRFFTRAMKVAGHVGVDEPFKGLFTQGMVVHETYKANGQWVSPADIRIEEIDGKRVATMLDSGAPVEIGSIEKMSKSKKNVVDPDDIIASYGADTARWFVLSDSPPERDVIWTEAGAEGAHRFVQRIWRLVAEAAPALKDVAPKAGTQGEALGVSKAAHKAVKAVGDDIEKLAFNRGVARLYELVNTLSGALQQAADGKADAEMKGALREATEMLVLMTAPMMPHLAEQCLAELGGKVAGKETLVARAPWPVFDPALVVENEIVLPVQINGKKRGDLTIARDADQASIQQAVLELDFVKAALNGGSPKKIIVVPQRIVNVVA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_ENT38
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQSGGKDPLVPEENDKTTVIALREIEEGLITNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ACO13_HUMAN
Sequence: MTSMTQSLREVIKAMTKARNFERVLGKITLVSAAPGKVICEMKVEEEHTNAIGTLHGGLTATLVDNISTMALLCTERGAPGVSVDMNITYMSPAKLGEDIVITAHVLKQGKTLAFTSVDLTNKATGKLIAQGRHTKHLGN
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16934754, PubMed:19170545).  Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates (By similarity) (PubMed:16934754, PubMed:19170545).  Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro) (By similarity) (PubMed:16934754, PubMed:19170545).  May play a role in controlling adaptive thermogenesis (By similarity).
What are the official names of this protein?
Acyl-coenzyme A thioesterase 13, Acyl-CoA thioesterase 13, Hotdog-fold thioesterase superfamily member 2, Palmitoyl-CoA hydrolase, Thioesterase superfamily member 2, THEM2.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During interphase, found both in the nucleus and in the cytoplasm. At mitosis, localizes to the spindle. Colocalizes with tubulin.