PharMolix/UniProtQA huggingface dataset:
Protein: VE8E2_HPV16
Sequence: MAILKWKLSRCYSSNEVSSPEIIRQHLANHPAATHTKAVALGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCTLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
What is the function of this protein?
Plays a role in limiting the replication of viral DNA in keratinocytes.  Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.
What are the official names of this protein?
Protein E8^E2C.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E8^E2C protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: TTC9C_BOVIN
Sequence: MEKRLQEAQLYKEKGNQCYREGKYRDAVSGYHRALLQLRGLDPSLPSPIPNLGPQGPALTPEQENLLHTTQTDCYNNLAACLLQMEPVNYERVKEYSQKVLERQPDNAKALYRAGVAFFHLQDYDQARHYLMAAVNRKPKDANVRRYLQRTQLELSSYHRKEKQLYLGMFG
What are the official names of this protein?
Tetratricopeptide repeat protein 9C, TPR repeat protein 9C.
What is the protein family that this protein belongs to?
Belongs to the TTC9 family.
Protein: RPPH_CERS5
Sequence: MERVIDPEALPYRPCVGIVLINREGLIFAGQRIDSPVPAWQMPQGGIDADEKPRQAALRELQEETGIPEDLVEFVAKAPEWVTYDLPPDLLGRVWGGKYRGQRQKWFLFRYLGTDEQIGIATEHAEFSCWRWIGAEEMVASIVPFKRPVYERVVAMFREHLS
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: HISZ_PSEPW
Sequence: MATVDRWLLPDGIEEVLPPEAARIEIARRQVLDLFQSWGYELVVTPHIEYLESLLTGAGQDLDQRTFKVVDPQSGRLMGFRADFTPQVARIDAHTLRREGPSRLCYAGSVLHAQPRALSTSRSPIQLGAELYGDASPTSDVEVISLMLATLQLTDVADVHMDLGHVGIYRGLARAAGLSGAVEQQLFDALQRKSVDEVQALTADLPKDLGNMLRALVELCGGREVLAEARVRLGRAPASVLAALDDLLAIADRLASRYPELPLYFDLGELRGYNYHTGVVFAVFVPGEGQSIAQGGRYDDIGADFGRARPATGFSTDLKTLVTLGRAEVVLPAGGIWMPDSGDAALWQQVCQLRNEGQRVVQALPGQPLSAALEADCDRQLIQQDGRWQVLPLTH
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK18_THAPS
Sequence: MKFSKRVLLRLKNKNKKLKPDKYKKLKRESVRGLIKGTVERPRLSVFRSNENIYAQIIDDTTAKTLVFCSTLDRDIKLNSENGRTCDASRLMGQKLAKLSIKKNITKIVFDRGPYLYHGRIKALADGARAGGLQF
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GRFIN_GRISQ
Sequence: SLTHRKFGGSGGSPFSGLSSIAVRSGSYLDXIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDYIDNISFETNMGRRFGPYGGSGGSANTLSNVKVIQINGSAGDYLDSLDIYYEQY
What is the function of this protein?
Mixed specificity lectin with anti-HIV activity.  Binds to HIV envelope glycoproteins, including exterior membrane glycoprotein gp120, and inhibits viral entry into cells.  Binding to gp120 is dependent on gp120 being glycosylated, and is inhibited by mannose, glucose and N-acetylglucosamine.
What are the official names of this protein?
Griffithsin, GRFT.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: ATPL1_CERS1
Sequence: MGKFIGAGLATIGLGGAGIGVGHVAGNFLAGALRNPSAAPGQMANLFVGIAFAEALGIFSFLIALLLMFAV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c 1, ATP synthase F(0) sector subunit c 1, F-type ATPase subunit c 1, F-ATPase subunit c 1, Lipid-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y5670_DICDI
Sequence: MIIDIEIWIQLFFFNNYNNYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0283779.
Protein: RL27_STAAM
Sequence: MLKLNLQFFASKKGVSSTKNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RL21_ALKEH
Sequence: MYAVIKTGGKQYKVSEGDVLRVEKLAGEAGASVEFDQVLMVGEGDDVKVGAPTVEGGKVTAEVLGQGRARKIEIQKFKRRKQYRRFAGHRQQFTEVKITGISAG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: DDL_STRU0
Sequence: MSKQTIVLLYGGRSAEREVSVLSAESVMRAINYDKFHVKTYFISQAGDFYKTQEFTVQPSESEKLMTNASLDASLKIKASDIYEDKAVVFPLLHGPMGEDGSIQGFLEILKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVNYTVYIEGNDLEDCITETLETLSFPIFVKPANMGSSVGISKAESIEGLREAIALALKYDSRILIEQGVVAREIEVGLLGNTKVASTLPGEVIKDVAFYDYQAKYIDNKISMAIPATIDEGITSQMRYFAEQAFKAIGACGLSRCDFFLAEDGNLYLNELNTMPGFTQWSMYPLLWDNMGLSYSDLIEELVSLAEEMFQKRESHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_PSESM
Sequence: MSLTEARFHDLVDATQQNIEDVFDESGLDVDLENSAGVLTVKFEGGSQLIFSRQEPLRQLWLAAKSGGFHFDYDEEESRWACDTSDELLSEMLARMTFEQAGADLDFSEI
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: TRM13_ASHGO
Sequence: MEASSLVAERPTGGEQDPGHARCAFYLPRKRRSCGMAPKAGARFCAEHQPGDSGTAARVPCPLDPRHTVAKAQLRSHLARCNRTKQDQALRAEREHMPWYEAGVNSAARPAAAAADEATLQAAVMRAIPVLAQIAEAEFRAPLRVAVLSNAQVEHVRFPQLPSNRKHALQQSSLIQHLREAGLWVAPERPVAYVEFGCGRGELSRYINQAAVLEQLERGGPAAPPAFVLVDRACPRMKFDSKFAEDVAELHARFCPSVPPDERPAPAVTRKKIDIRDLRLAALLSPGLEHIAVSKHLCGVATDLTLRCLAAGPRASLCGALIAMCCRHACNPAEYANPAYVEALLARHAPDMSYDLFFLALMKMASWAVSGRRPGVPDTEVGGHFSGLAIAERERLGHLARRLVDEGRRQYFADLGYDAELLVYCERDTSREDIALLVRRPA
What is the function of this protein?
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
What are the official names of this protein?
tRNA:m(4)X modification enzyme TRM13, tRNA methylase 13.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase TRM13 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: PFF1_CANDC
Sequence: MPQEEVHDTSSVSDDNLTNTGGGGSNYYNSHNQPNVFVRAIRSIFGYRKTSLTLFVILTIIFTIALSLYDNNLDLTIELPTNKLENEILKSSWLDLQNIARYPHTYGSRANDRVHDYLESRIHDIIKENPYTEYNNDGEKVLYESAKSIVSYYESNNLLVRINGSDASLPALLLSAHYDSVPSSFGVTDDGMGIASLLGVLRFFAQNEQPRRTVIFNFNNDEEFGLYGAQAFVSHPWFKQIGFFLNLEGTGAGGKAILFRGTDYGIVKYFNKVRYPYATSIFQQGFNNHLIHSETDYKVYKEAGLRGLDLAFYKPRDIYHTAEDNIKNINLKSLWHMLSNSIDFANFVSNQKINDSGKDEFAVYTSFLGYFFSSPISALVTINSVLIVLFPILSGPLLFITVRYKKWKIGTSNFLSLPLAIVLTVAIVMIVVNQGFQIANPFLPSSHPLLLVATTTSISLLIYYVFLNGVNWVSPSGDQKLITIIEISFIYWLILIYVTHGLSQNKIGDDHTGEFPFTVLFFLEATASLFGLIGWTFSRSIKQSSNDGSDEPLLTGTAERYGSDDTDEDEQEEFRHHDGNTVKHLMQHFGYDWSLQYLLIVPISSLIIFNSGWLVLDGINKSIQESFAAENLIYLLIQLFSQFWILPILPFVYKLNRFIVFGLTIFAISGVALISFLDPFNQENPLKLRFIQKVDLNKSQDSFVEVYGRKGIFSDILSDMPSVKETHTKVECEALSDGLEACSYKSALAPNVIPGKSLKDYVNVEIVNSSKIESYGLLSGEIIITAPENRMCTLYFTKKKVKAVVIYNKSKSVNNFKSIPDGFSRDSKGNYIYKDVAGIDQLVLNKLDWNKNYHIGFDWLPNIDDEVNTLSVDVECYWADLAPGIGGGDNATNAELAIPAYNELVHYSPNWVTWANREKGLVSVSLKIEV
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RL1_HAHCH
Sequence: MAKLTKRQKAIREKVQAGKAYSVEEAVALLTELSAPVKFKESIDVSVNLGVDARKSDQVVRSSTVLPNGTGKTVRVAVFTQGANADKAKAAGADIVGMDDLAEEVKKGNLDFDVVIATPDAMRVVGQLGQILGPRGLMPNPKVGTVTADVEAAVNNAKAGQIRYRTDKNGIIHAPLGNVEFSAEHIKQNLEALIADLKKIKPSSAKGVYLKKVTLSSTMGPGLLIDQNSLAV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PYR7_ASPFU
Sequence: MSVQTTYSPVNQDEQVHDGLASRHVSCEGAPSDDSPYALSSLDHNPLGINVSFLLCFHAAQPEEGIRVLEDGINQLLKAHPFLAGDVTRPTRLSQRTNTMQIEPDAPESLLKIPMLQIRHHPATSIEELESKRLLPGAEEQEIIRQLAPLPIDMDLSLPQRPVLRFQANIMRDGVILAMTFHHAAMDGAGAARVLGLLADYCRDPAAPSVGVIPDRQLRSQIDRLATGCSPSASRADFSQHYCGLGDWAALLAENWPGFLQARATELVTWRLTIPGFKVQYLKGACNALLQGQTSALAGGTLTPTILSNNDIVSALMAMILRQAGQLAGKSTELSIAVDMRPSFHAPAFNNYLGNMVLLTYTPIPAAKDQAPVDGPRPPTELRQEDLEELTGIAARIRQSLLKVDAEYIQGVLSHLHSQTDWANIGFRGVPIPLSSFRNFEMIGLDFGETLGSQPRGFQLHLPVLGGMCFVLPKRQDRTEPWDLHLTLHRDDVSRIANDPLFRWAAGEHF
What is the function of this protein?
O-acetyltransferase; part of the gene cluster that mediates the biosynthesis of pyripyropene A, a specific human acyl-coenzyme A:cholesterol acyltransferase 2 inhibitor (PubMed:20861902).  The first step of the pathway is the synthesis of nicotinyl-CoA from nicotinic acid by the nicotinic acid-CoA ligase pyr1 (PubMed:20861902).  Nicotinyl-CoA is then a substrate of polyketide synthase pyr2 to produce 4-hydroxy-6-(3-pyridinyl)-2H-pyran-2-one (HPPO) which is further prenylated by the polyprenyl transferase pyr6 to yield farnesyl-HPPO (PubMed:20861902).  The next steps consist of an epoxidation of farnesyl-HPPO to epoxyfarnesyl-HPPO by FAD-dependent monooxygenase pyr5 and a cyclization of the terpenoid portion by the terpene cyclase pyr4 to yield deacetyl-pyripyropene E (PubMed:20861902).  The 2 cytochrome P450 monooxygenases pyr3 and pyr9, and the 2 acetyltransferases pyr7 and pyr8 are involved in the conversion of deacetyl-pyripyropene E into pyripyropene A through several cycles of oxidation and acetylation steps (PubMed:20861902).  Pyr7 acetylates deacetyl-pyripyropene E to pyripyropene E which is oxidized to 11-deacetyl-pyripyropene O by pyr3, which is in turn acetylated into pyripyropene O by pyr8 (PubMed:21224862, PubMed:26019565).  Pyripyropene O is then oxidized to deacetyl-pyripyropene A by pyr9 (PubMed:21224862).  Deacetyl-pyripyropene A is finally acetylated to pyripyropene A by pyr8 (PubMed:26019565).
What are the official names of this protein?
O-acetyltransferase pyr7, Pyripyropene synthesis protein 7.
What is the protein family that this protein belongs to?
Belongs to the fumigaclavine B O-acetyltransferase family.
Protein: EUTB_ECO57
Sequence: MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase large subunit, EAL large subunit.
What is the protein family that this protein belongs to?
Belongs to the EutB family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: EFEB_YERPN
Sequence: MRDKTGPKFGPYQPDDEAVSPSRRRLILGMGMVSGALVLGGAKTAQAADCRSPDVAGTQDERWQKQPFYGQHQAGVLTPQQAAMMLVAFDVLATDKTSLIRLFKLLTERLAFLTTGGRAPSVNAKLPPLDSGIMGPEIYPDNLTVTVSVGNALFDERFGLQGQKPLRLQRMTRFPNDSLDAGLCHGDVMLQICANTNETVIHALRDIIKHTPDLLSVRWKREGFISAHAARSKGQDTPINLLGFKDGTANPKISNKPLINNVVWVSNNAGEPAWAVGGSYQVVRIIRFKVEFWDRTPLQEQQTIFGRDKNSGAPLGMQHEHDEPNYAKDPEGKVIPMDAHIRLANPRTIETQRNLMLRRGYSYSLGVSNSGQLDMGLLFVCYQSDLAQAFLTVQERLNGEALEEYVKPIGGGYFFTLPGVADANHYLAQSLLEA
What is the function of this protein?
Involved in the recovery of exogenous heme iron.  Extracts iron from heme while preserving the protoporphyrin ring intact.
What are the official names of this protein?
Deferrochelatase, Peroxidase EfeB.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family. EfeB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: LON1_THET2
Sequence: MKDFLRLELPVLPLRNTVVLPHTTTGVDVGRLKSKRAVEEALSADRLLFLVTQKDPEVDDPAPEDLYAVGTLAVVKQAMRLPDGTLQVMVEARSRARLLSYVAAPYLRAVGEAIPEPPLKDPELARVLVNEVQEAFERYLQNHKTLRLDRYQQEAVKSTRDPAILADLVAHHATWTLEEKQTILETPEVEERLKRVLALLLRDLERFELDKKIAARVKEQMDQNQREYYLREQMKAIQKELGGGEDFLTEIEELRERIEKKGMPEPVKEKALKELKRLERMQPGSPEATVSRTYLDWLLEVPWTEADPEVLDISVTKRVLDEDHYGLKEVKERILEYLAVRQLTQGKEVKGHAPILCFVGPPGVGKTSLGKSIARSMNRRFHRISLGGVRDEAEIRGHRRTYIGALPGKIIQGMKQVGVVNPVFLLDEIDKLSSDWRGDPAAALLEVLDPEQNHTFTDHYLDVPYDLSKVFFITTANTLSTIPRPLLDRMEVIEIPGYTLHEKRAIARYFRWPFQVKEAGLEGRLEITDRAIERIVQEYTREAGVRNLDRELSKVARKAAKDYLEKPWEGVRVVDAEDLEAYLGVPKYRPDRAEKEPQVGAAQGLAWTPYGGTLLTIEAVAVPGTGKVNLTGNLGEVMKESAHAALTYLRAHREEWGLPEGFHKDYDLHIHVPEGATPKDGPSAGITIATALASALTGRPVRMDIAMTGEITLRGRVLPIGGVKEKLLAAHQAGIHRVILPKENAAELKEVPEEILKDLEIHFVEEVGEVLKLLLLPPPPPPAVQPDRPQPGVGA
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease 1, ATP-dependent protease La 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_BACMK
Sequence: MENIHIQTKSKEYDVHVGREALSHLTTLIQKMNPAVSNIMIISDEAVASLHLQTAVDALQVEQKVFSFVVPSGEKEKSFENFYEAHTSALENKLDRNSLIIALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLHSLPEKEWRSGYAEVIKHALIGDVELYHWLKEEVQTLTDLRDEKLIHILTKAIPVKANIVSQDETEKGIRAHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAMFLSEQVYKVDLSYEEMKQWFLKYGYPKMPSDLNVERLVQLMKQDKKANAGTIHMVLMQEYGGVNVVSISDETVHIALEAFQKDMV
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_METTH
Sequence: MRNIIVEPLNQTPIEDQKVEIVERKGIGHPDSISDGIAESVSRALCNAYLDRFGAIMHHNTDEVQITAGESAPQFGGGEVIKPMEILLTGRGIAEVDGEKIGLDRIAISAAKEYLRENILNLDVETCAVVECKIGHGSGDLRDVFARKGRAPLSNDTSFGVGFAPFSETERIVMEAENLLNSPEFKKKHPAVGEDIKVMGLRENDNITLTVACAMVDRYVSDLEEYLEVKNVVRDEVFKIASKLTDRNLEVFVNTADRCEDDEPSVYITVTGTSAEMGDDGSVGRGNRANGLITPNRPMSMEATSGKNPINHVGKIYNLLSNQMAGDIVESVEGVKQVHIMILSQIGKPIDHPKAATAQVILEDGYTMDEVTGKVSGVMDAWLEDIPSITEMLVKGQLRTF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: SCPB_CLOBJ
Sequence: MNKDHEEQLEINEVSQKNKYKSIIESLLFMSGEPINIKDLATILNCKQDKVSSLLNEMKNSYVGKDRGIKILIHNRAVQLVTKPENSIYVEKLLKTNIRQSLSQAALETLSIIAYKQPITRVAIDEIRGVKSDRAIYTLLEKNIIKECGRLDVPGKPILYGTTEEFLKFFGLDSIEAIPNLEDLLKEFSKEEN
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: KI2S1_HUMAN
Sequence: MSLTVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVMFEHFLLHREGMFNDTLRLIGEHHDGVSKANFSISRMKQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVIIGLYEKPSLSAQPGPTVLAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAGTKVNGTFQANFPLGPATHGGTYRCFGSFRDSPYEWSKSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQEVSYA
What is the function of this protein?
Receptor on natural killer (NK) cells for some HLA-C alleles such as w6.  Does not inhibit the activity of NK cells.
What are the official names of this protein?
Killer cell immunoglobulin-like receptor 2DS1, CD158 antigen-like family member H, MHC class I NK cell receptor Eb6 ActI.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Y1624_CLOAB
Sequence: MEKIALITDSTSDVDKDMIEKYDIKVLPLRIIYKDKEYIDRVTISPREVYDNLHIEVPSTSLPSMGDMESLYEKLEAEGYTHVIGVTISSNLSGTYNSLKLVSEGHENIKSFIFDSRSITMGEGAIIKECGEMILQGKNFDYIVEKMPKMRENIKVYYIVDTLKYLIKGGRIGKVSGTVGQLLDIKPIISINEEGVYYTHCKAKGKKQAIKKLIEILRRTLSEKHCDIWVMHGGAYDEIDKLKDLVSGIENINNLNSGEISPVAGVHTGPGLLGVVIFKK
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein CA_C1624.
Protein: RS2_STRPQ
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLTNWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVMYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLADAIIEGRQGEDADVAFEADTQADSIEDIVEVVEGDNA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MCCC7_ECOLX
Sequence: MRTGNAN
What is the function of this protein?
Antibacterial peptide, active against enterobacteria including species of Klebsiella, Salmonella, Shigella, Yersinia and Proteus, and strains of E. coli.  Inhibits protein translation by blocking aspartyl-tRNA synthetase function and inhibiting production of aminoacetylated tRNA-Asp.
What are the official names of this protein?
Microcin C7, MccC7, Microcin C51, McC, MccC51, Microcin C.
Protein: RSMG_MYCMS
Sequence: MFSNWDIFLNYKNFTINQEIKNKLDLYYQILIQENQKYNLTRITELNEVFEKHFLDSLLFVEQFQIIDQKIADIGTGAGFPGIVLKIFFPNIKLTLIESNNKKANFLKYLVQKLELNNVEILNKRAEELNEYKEHLI
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNGA4_HUMAN
Sequence: MSQDTKVKTTESSPPAPSKARKLLPVLDPSGDYYYWWLNTMVFPVMYNLIILVCRACFPDLQHGYLVAWLVLDYTSDLLYLLDMVVRFHTGFLEQGILVVDKGRISSRYVRTWSFFLDLASLMPTDVVYVRLGPHTPTLRLNRFLRAPRLFEAFDRTETRTAYPNAFRIAKLMLYIFVVIHWNSCLYFALSRYLGFGRDAWVYPDPAQPGFERLRRQYLYSFYFSTLILTTVGDTPPPAREEEYLFMVGDFLLAVMGFATIMGSMSSVIYNMNTADAAFYPDHALVKKYMKLQHVNRKLERRVIDWYQHLQINKKMTNEVAILQHLPERLRAEVAVSVHLSTLSRVQIFQNCEASLLEELVLKLQPQTYSPGEYVCRKGDIGQEMYIIREGQLAVVADDGITQYAVLGAGLYFGEISIINIKGNMSGNRRTANIKSLGYSDLFCLSKEDLREVLSEYPQAQTIMEEKGREILLKMNKLDVNAEAAEIALQEATESRLRGLDQQLDDLQTKFARLLAELESSALKIAYRIERLEWQTREWPMPEDLAEADDEGEPEEGTSKDEEGRASQEGPPGPE
What is the function of this protein?
Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs).  CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation.  By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity).
What are the official names of this protein?
Cyclic nucleotide-gated cation channel alpha-4, Cyclic nucleotide-gated channel alpha-4, CNG channel alpha-4, CNG-4, CNG4.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA4 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YO42_CAEEL
Sequence: MTSRRIINREQRQCSQIRPYLYVSGLAALSPRVLSRFCVCINLIPGFRLSAPPHMKVVHLPLQDNETTDLSPHWANVYKEIEEARKGAGRALLLCAMGISRSATFGIAYVMQYEKKTLHDSYKAVQLARNIICPNVGFFQQLIDLEQKLRGKVSCKIIEPLPGCKVPDVIWQELYDEMIMSMSQDDRHSLASCNLSARSTTNDTMSLRSLNMVNDTSRSLASFHLTHRPIGASPTLLVPSSSSSSSVRGPIPLQRAHTEPPKEASILPKSALRDKSKSGEKKKKWRLSFHKDVV
What are the official names of this protein?
Uncharacterized protein ZK757.2.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: 3SIM4_DENAN
Sequence: LTCVTSKSIFGITTENCPDGQNLCFKKWYYIVPRYSDITWGCAATCPKPTNVRETIHCCETDKCNE
What is the function of this protein?
Binds to the muscarinic acetylcholine receptor (CHRM).
What are the official names of this protein?
Muscarinic toxin 4, MT4.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Aminergic toxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THIO1_CHLTE
Sequence: MAQTLDDLIRTSELPVFIDFWADWCGPCKMVAPSVKQLASEFKGRLIVVKVNVDQQPDAAARFQVQGIPALMLFVGGQLKWRTAGAIPYQQMRQEVLKAIG
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin 1, Trx-1.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.