PharMolix/UniProtQA huggingface dataset:
Protein: NOS_LYMST
Sequence: MGSLSQQAHGPPDAPRSKEELLIHAKDFINQYFTSFQMNKTRAHFHRLGEINDLIEKSGTYDLTMAELTFGAKHAWRNAPGCIGRSQWSKLQVFDAREIGTPREMFEALCSHIRYATNEGKIRSTITIFPQRKEGRPDFRVWNTQLISYAGYKLGDGKVIGDPANVEFTEMCVEMGWKPKHGMFDLLPLVLSAAENSPEYFELPTELVLEVTLKHPEYPWFAEMGLKWYALPTDSGMLLDCGGLEFPSCPFNGWFMGTMIGSRNLCDPHRYNMLEPIGLKMGLNTETASSLWKDRVLIEVNVAVLYSFESANVTIVNHHDASTDFISHMDKEIKLRGGCPSDWVRMVPPMSGSTLEVFHQEMLLYNLHPAFVRQDVKPWKKHVWKSDQSVPINSCNPKRKLGFKALARAVEFSASLMSKALSSRVKCSIFYATETGRSERFARRLSEIFKPVFHSRVVCMDDYAVETLEHESLVMVITSTFGNGEPPENGKQFAQSLLDMKRKYDCDLGFLESCSSISTCIKSSILTEGPLAADVIGDRQSLAMGTGPLCNVRFAVFGLGSKAYPYYAAYGKYIYLMLQELGAERLVNYCAGDALYGQEQSFRAWSEEVFKASCEAFCLDNRNDAPGPQTKGDCSKVRIVPVENCQEPDLCQVLRNIHGKEVMPLILAERIQLQAKDSDQQTILIKLDAHNATDLKYAPGDHVAIFPANSPEIVDAILVRLDTSKGPSPDQVVKTEISTQLGTNDTWRSHLPICTSRTAFSFLLDVTTPPSQEILQVLATQASSDMDKHKLEQLASNSEAYEKWRLDLSPNILEILDEFPSLKIPPSLLLTQLPLLQPRYYSISSSQQKNPNEVHATIAVVRFKTQDGDGPVHEGVCSSWLNRSPIGTVVPCFLRSAPHFHLPEDPSLPIIMIGPGSGIAPFRSFWQQRLGEIENTMPSCENTMLSCETTIPSCENSMPSCENTMPSCENTMPSCENTIPSCENTIPSCENTMPSCENTIPSWERTMQPCQIILPSQTKKHFGEMVLYTGCRTAKHMIYAAELEEMKRLGVLSNYHVALSREAALPKMYVQDIIIKNAAAVYEIVMKKGGHFYVSGDVSMAHDVTRALELVLCQQGGREASQQVMSLRDENLFHEDIFGSFVRKAGGQRSEDE
What is the function of this protein?
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
What are the official names of this protein?
Nitric oxide synthase, NOS type I, Neuronal NOS, N-NOS, nNOS.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
Protein: OTOP1_HUMAN
Sequence: MLEGLGSPASPRAAASASVAGSSGPAACSPPSSSAPRSPESPAPRRGGVRASVPQKLAEMLSSQYGLIVFVAGLLLLLAWAVHAAGVSKSDLLCFLTALMLLQLLWMLWYVGRSSAHRRLFRLKDTHAGAGWLRGSITLFAVITVILGCLKIGYFIGFSECLSATEGVFPVTHSVHTLLQVYFLWGHAKDIIQSFKTLERFGVIHSVFTNLLLWANGVLNESKHQLNEHKERLITLGFGNITTVLDDHTPQCNCTPPTLCTAISHGIYYLYPFNIEYQILASTMLYVLWKNIGRKVDSHQHQKMQFKSDGVMVGAVLGLTVLAATIAVVVVYLIHIGRSKTKSESALIMFYLYAITLLMLMGAAGLAGIRIYRIDEKSLDESKNPARKLDSDLLVGTASGSWLISWGSILAILCAEGHPRYTWYNLPYSILAIVEKYIQNLFIFESIHREPEKLSEDIQTLRVVTVCNGNTMPLASSCPKSGGVARDVAPQGKDMPPAANGNVCMRESHDKEEEKQEESSWGGSPSPVRLPRFLQGNAKRKVLRNIAAFLFLCNISLWIPPAFGCRPEYDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAASLFEVYCKI
What is the function of this protein?
Proton-selective channel that specifically transports protons into cells (PubMed:29371428).  Proton channel activity is only weakly-sensitive to voltage (By similarity).  Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes (PubMed:29371428).  In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration (By similarity).  Probably acts by maintaining the pH appropriate for formation of otoconia (By similarity).  Regulates purinergic control of intracellular calcium in vestibular supporting cells (By similarity).  May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol (By similarity).  Also involved in energy metabolism, by reducing adipose tissue inflammation and protecting from obesity-induced metabolic dysfunction (By similarity).
What are the official names of this protein?
Proton channel OTOP1, Otopetrin-1, hOtop1.
What is the protein family that this protein belongs to?
Belongs to the otopetrin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Detected in the gelatinous membrane overlying the inner ear macular epithelium.
Protein: FER2_RICBR
Sequence: MSKTIKVTFVINNGEEKIIEAPLGLSILEVAHSNSIDLEGACEGSLACATCHVILEEEFYNKLEKPKEEEEDMLDLAFGLTDTSRLGCQIILTEKLDGIKVRLPSATRNIK
What is the function of this protein?
Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
2Fe-2S ferredoxin, Adrenodoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
Protein: BGLH_ASPCL
Sequence: MTAKFDVDHVLNSISEDDKIALLSGTDFWHTYSIPEHNVPPIRTTDGPNGVRGTKFFAGVPAACLPCGTALGATWDRDLLHKAGVLLGQECLAKGAHCWLGPTINMQRSPLGGRGFESFAEDPHLSGTMAKSIILGCESTGVISAVKHYVGNDQEHERRAVDVMVTPRALREIYLRPFQIVARDAHSGALMTSYNKINGKHVVENPAMYDIIRKEWKWDPLIMSDWLGTYTTIDSLNAGLDLEMPGPSRYRGKYIESAVQARLVKQSTIDQRARKVLEFAARASQAPASAVESGRDYPEDRALNREICGNSIVLLKNEDTLLPLPKKIKKIALIGSHVKTPAISGGGSASLQPYYAVSLYDAIIEVLPDTEIIYETGAYAHKMLPVIDRMLSNAVIRFYNEPADKERTLLSTEPVNNTAFQLMDYNTPGLNRTLFWATLDGEFTPDVSGLWDFGLTVFGTATLYIDDEMVIDNTTQQTRGTAFFGKGTIQEVGAKELTAGRTYKIRIEFGSANTSPIKAIGVVHFGGGAAHLGAFLHMDPEQMVRDAVKAASEADYTILCTGLNRDWESEGFDRPDMDLPPRIDALISAVLDVAGDKTIIVNQSGTPVMMPWSDRARAIIQAWYGGNETGHGIADVLFGDVNPCAKLPLSWPADVRHNPAYLNSLSVGGRMLYGEDIYVGYRFYEKIGQVTLFPFGHGLSYTLFEVSPKVTVSPTAFTVETPLSATVRIKNTGPVAGAQILQLYVAAPTSATPRPVKELQGFSKVFLQSGEEKTVVISVDKYATSFWDGIEDMWKSEAGVYQVLIGTSSQDIVARGEFTVDETTFWTGV
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase H, Beta-D-glucoside glucohydrolase H, Cellobiase H, Gentiobiase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD_WOLWR
Sequence: MCFGLPNINREGYSFIVVSFIVTCIAFSISWGFGVTCLFPTLLCTYFFRDPARAVPNNKNLILSPADGVISKIEEVNYPLSAENGEEKKFTLVSIFLSVLNVHVNRIPISGTIKEMSYKKGKFVSAMSNRSSNENEKQVIVIEYEKGKEIIVEQIAGLIARRIVCNLGISQNVKAGERFGIIRFGSRVNIYVPADTEVRVSEGQTVIGGETIIANLNKENVQEKLTFDVI
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y415_SYNY3
Sequence: MRFRCYLIFSIFSDSLLGAGFFQGGKRAMVVSTPIAAEEKPPIQANVVETWEISKIYRTGFWMNQKVESLKPLSIAVQQGETFGLLGPNGAGKTTLLKILLGVIRASGGRGTLLGKPIGDRQTKQRVGYLPENAYFYDFLTAWEFLDYIGSLFQIGKQERQRRILAMCDLVGLAQKTAKKKQLRQYSKGMLQRVGMAQALINDPEVVFLDEPMSGLDPLGRYQVREIILSLKEQGKTIFFNSHILADVEQICDRIAILARGELLCSGSLAEVLGNDEGYEVVLKGGEEEALGKYLANLSQEQDVWHGHYQGDVQALVDALPSLNARLISMNLARPSLEDYFIRQLRERGITTSQ
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein sll0415.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: FLHD_BORPE
Sequence: MKTADSSLLADIREVNLSYLLLAQRMLRDDYAASMFRLGFSNEVADILMRLSPAQLVKLANSSSLLCRFRFDDYSLLSALTQDVLGGALQQAHATILLARQPVEELA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_CLOP1
Sequence: MRYNAGSYDIVVIGAGHAGCEAGLAAARMGCKTLVCTLTLDSVAMMPCNPNIGGTAKGHLVREIDALGGEMGVNIDHTFIQSKMLNTSKGPAVHSLRAQADKKKYQERMKKVLETQENLHLRQLEVVSVEVEDGKVKGVLTKNGAFFECKAVIMTSGTYLQSRIIIGDVSYSQGPNGLSNANELSKSLIDLGIDLRRFKTGTPARINKRSVDFSKMIEQPGDEEIIPFSFISGNIDRDQVSCWLTYTNEETHKVIQENIHRSPMYNGSIKGVGPRYCPSIEDKVMRFQDKDRHQIFIEPEGDDTEEMYVGGMSSSLPEDVQVQMIKTVPGLENAEIMRTAYAIEYDCIDPTQLKASLEFKNIDGFFSAGQINGSSGYEEAGAQGIVAGINAALKVQGKDPMILTRSDGYVGVLIDDLITKGTNEPYRMMTSRAEYRLLLRQDNADFRLTEIGHNVGLVTEERWSKFQERKQNLERELERLKELQITNKTENNEKIVELGSTELKKPIRMYELIKRPELDYFSLACLDPERPDLPKDIGDQINIIARYEGYIQTQLEQVAQFKKFEKKVLPEDLDYNDVNSLRIEAIQKLNKIRPLNIGQASRISGVSPADISVLLIFLEHYRKTGKNTDN
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_DEIRA
Sequence: MTTADQPQAVRDDAVFDLIAQEAERQRTGLELIASENFTSAAVREAQGSVLTNKYAEGYPGKRWYGGCEVVDQVEQLAIDRVKQLFNAEWANVQPHSGSSANLAVYNALIQPGDTVLGMDLSHGGHLTHGNKANFSGMRYQMVAYQLDRETERIDMEEVRRLAHEHKPKMIIAGASAYSRVIDFAAFREIADEVGALLFADIAHIAGLIAAGEHPNALPHAHVVASTTHKTLRGPRGGIILANDPEIAKQLDRTVFPGYQGGPLEHVIAAKAVAFGEALRPEFKDYARQIIKNAQALAGEFQQKGYRVVSGGTDNHLFLLDLRPQGLNGTKATRLLDANHITISKSTLPYDTEKILHGGGIRIGTPAVTTRGMTEAHMTQVADLIDRALKGEDVQAKVHDFAGGFPLP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2904_NOVAD
Sequence: MSADSAPQRILLVTGLLGAGKTTALRTLEDMGWEAIDNFPIRLLDRLLETEPGSARMEPGAPMAIGFDTRTRGFDPSRTIELVKKLSQRSDLQITTLFLDCAGTELERRYNETRRRHPMSEDKPAATGIAAERELLEPLRRWADVVITTTSFTTNDLQQAIRDQFGGEIATPTTITISSFGFSRGMPPLADLVFDMRFLANPHWVDDLRPQTGRDKAVGEYIRKDPAFDEAFERIRDLLLLLLPRYQEQGKAYVHIAFGCTGGRHRSVFMAEQIASALREAGFSPTLLHRNLSSRAADLLEGVKG
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Saro_2904.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CAT7_MOUSE
Sequence: MTPTVFLSILCLGVALAAPAPDYNLDAEWEEWKRSNDRTYSPEEEKQRRAVWEGNVKWIKQHIMENGLWMNNFTIEMNEFGDMTGEEMKMLTESSSYPLRNGKHIQKRNPKIPPTLDWRKEGYVTPVRRQGSCGACWAFSVTACIEGQLFKKTGKLIPLSVQNLMDCSVSYGTKGCDGGRPYDAFQYVKNNGGLEAEATYPYEAKAKHCRYRPERSVVKVNRFFVVPRNEEALLQALVTHGPIAVAIDGSHASFHSYRGGIYHEPKCRKDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGERWGENGYMKLPRGQNNYCGIASYAMYPAL
What is the function of this protein?
Involved in trophoblast cell proliferation and differentiation probably by affecting mitotic cell cycle progression.  Proteolytic activity and nuclear localization are essential for its role in cell cycle progression.
What are the official names of this protein?
Cathepsin 7, Cathepsin 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Endosome. Lysosome. Cytoplasm, perinuclear region. Golgi apparatus. Nucleus. Secreted, extracellular space.
Protein: VIRB5_BRUME
Sequence: MKKIILSFAFALTVTSTAHAQLPVTDAGSIAQNLANHLEQMVKFAQQIEQLKQQFEQQKMQFDALTGNRGLGDILRDPTLRSYLPHNWRDLYEAVMSGGYLAAAGETANLLRKSQVYDPCASISDKDQRIACEAKVVKPVQDKVMTSKAYDATDKRLQEIESLMQEINKTGDPKAIAELQGRIESENAMIQNEDTRLHLYQQMAEAQDKLLDERQHELDAKDNARRGYPQPKALEAAY
What are the official names of this protein?
Type IV secretion system protein virB5.
What is the protein family that this protein belongs to?
Belongs to the virb5 family.
Protein: RS7_DESA1
Sequence: MSEMQTREMLIGEIKLFNKWSYDFIEVRDPSLKKYICLKPVYLPHSGGRHEHKRFGKALVPIVERLINNVMRPGRNMGKKHLAYNIVKKSFELIYLKTGENPLQVLVRAIENAAPREETTRIMYGGITYHVSVDIAPLRRIDLALRHLTEGARLKAFHNPISIEEALAEEIALAASNDPKSYAVQKKEEIERIALSSR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SLE1_STAES
Sequence: MQKKYITAIIGTTALSALASTHAQAATTHTVKSGESVWSISHKYGISIAKLKSLNGLTSNLIFPNQVLKVSGSSSRATSTNSGTVYTVKAGDSLSSIAAKYGTTYQKIMQLNGLNNYLIFPGQKLKVSGKATSSSRAKASGSSGRTATYTVKYGDSLSAIASKYGTTYQKIMQLNGLTNFFIYPGQKLKVPGGSSSSSSSNNTRSNGGYYSPTFNHQNLYTWGQCTWHVFNRRAEIGKGISTYWWNANNWDNASAADGYTIDYRPTVGSIAQTDAGYYGHVAFVERVNSDGSILVSEMNWSAAPGNMTYRTIPAYQVRNYKFIH
What is the function of this protein?
Peptidoglycan hydrolase involved in the splitting of the septum during cell division.
What are the official names of this protein?
N-acetylmuramoyl-L-alanine amidase sle1.
What are the subcellular locations of this protein?
Secreted. Cell surface.
Protein: CLPP2_PROMP
Sequence: MPIGTPSVPYRLPGSQYERWVDIYTRLGVERILFLGQEVNDGIANSLVAQMLYLDSDDNTKPIYLYINSPGGSVTAGLAIYDTIKYVKSDVVTICVGLAASMGAFLLGAGTKGKRVALPHSRIMIHQPLGGTSQRQASDIEIEAREILRIKDMLNHSMSDMTGQSFEKIEKDTDRDYFLSAEEAKNYGLIDRVISHPSEAS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4336_PSEF5
Sequence: MLIPHDQLEVDTLTRLIEDFVTREGTDNGDETPLETRVLRVRQALTKGQAVIVFDPDSEQCQLMLKHDVPKELFD
What are the official names of this protein?
UPF0270 protein PFL_4336.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: ACP_DEHMB
Sequence: MATVFERVKKVSVEQLGAEEKDVVLTASFADDLGADSLDQVELIMALETEFGTPETKFEIPDTDAEKLKTVQAVVDYLKSKGIKDS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX10B_MANRB
Sequence: MRLSYISLTLAIIFVMAIVHAPETEAKAYPEADAVAEAIAVGEADAVGVADPGIKDALAKIWKILKAEVPTVAAAIENKVG
What is the function of this protein?
Induces paralysis after injection into blowflies (L. caesar), and then death within 24 hours (PubMed:32182430).  May have antimicrobial properties, like most ant linear peptides (By similarity).
What are the official names of this protein?
U10-myrmicitoxin-Mri1b, U10-MYRTX-Mri1b.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YADA1_YEREN
Sequence: MTKDFKISVSAALISALFSSPYAFADDYDGIPNLTAVQISPNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENTNKRSAELLANANAYADNKSSSVLGIANNYTDSKSAETLENARKEAFAQSKDVLNMAKAHSNSVARTTLETAEEHANSVARTTLETAEEHANKKSAEALASANVYADSKSSHTLKTANSYTDVTVSNSTKKAIRESNQYTDHKFRQLDNRLDKLDTRVDKGLASSAALNSLFQPYGVGKVNFTAGVGGYRSSQALAIGSGYRVNENVALKAGVAYAGSSDVMYNASFNIEW
What is the function of this protein?
Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface.  Promotes initial attachment and invasion of eukaryotic cells.  Also protects the bacteria by being responsible for agglutination, serum resistance, complement inactivation and phagocytosis resistance.
What are the official names of this protein?
Adhesin YadA, Type 5 secretion system autotransporter YadA.
What is the protein family that this protein belongs to?
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
What are the subcellular locations of this protein?
Cell surface. Cell outer membrane. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface.
Protein: UH105_ALTSL
Sequence: MNHTKLKLSAVALTLALGLSACSGESPEKQVQSAESEQMKAVDVDKSMPMQSIESTAKRIGESAANWQIAQFGNLDYIPESHRAKSENAKFWIQASFYIGLTRWIDATDDKQLESFVKQVAEKENYELILERPYHADDHAIAQTYLWLAERAGVQEAYMPTKEVFDMILSKPPQVGLNMGDSESSSGKYHLEGNCQLRWCWADALFMAPRAWAQMTKVTSDPKYLEYGNKEFWAAADYLFSDEYGLFFRDSRYFDAKSDNGEPVFWGRGNGWVFAAIPMIIEELPEGHPSKDRYIELYKKHAEGLMALQKEDGYWPASLMDPDKVRTPEVSGTGFITFGLAWGVNNGILTDQRSKDVVEKGWSAITKAVTDDGRVNWVQHVGKSPDPVKESDSQLYGTGAVLLAASEMLIWNK
What is the function of this protein?
Glucuronyl hydrolase involved in ulvan degradation.  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl).  Unsaturated 3S-rhamnoglycuronyl hydrolase works together with ulvan lyases to fully degrade the ulvan polymer, catalyzing specifically the cleavage of the unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) of the deltaUA-oligosaccharides deltaUA-Rha3S, deltaUA-Rha3S-IduA-Rha3S and deltaUA-Rha3S-Xyl-Rha3S, the end products of the ulvan lyase reaction.
What are the official names of this protein?
Unsaturated 3S-rhamnoglycuronyl hydrolase, Ulvan hydrolase, Unsaturated beta-glucuronyl hydrolase, UGL.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 105 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DPP5_PORG3
Sequence: MNKKIFSMMAASIIGSAAMTPSAGTNTGEHLTPELFMTLSRVSEMALSPDGKTAVYAVSFPDVKTNKATRELFTVNLDGSGRKQITDTESNEYAPAWMADGKRIAFMSNEGGSMQLWVMNADGTERRQLSNIEGGITGFLFSPDEKQVLFTKDIKFGKRTKDIYPDLDKATGRIITDLMYKHWDEWVETIPHPFIANATDGMITTGKDIMEGEPYEAPMKPWSGIEDFSWSPDGQNIAYASRKKTGMAYSLSTNSDIYIYNLTSGRTHNISEGMMGYDTYPKFSPDGKSIAWISMERDGYESDLKRLFVADLATGKRTHVNPTFDYNVDMIQWAPDSKGIYFLACKEAETNLWEITLKTGKIRQITQGQHDYADFSVRNDVMLAKRHSFELPDDLYRVNPKNGAAQAVTAENKAILDRLTPIACEKRWMKTTDGGNMLTWVVLPPDFDKNKKYPAILYCQGGPQNTVSQFWSFRWNLRLMAEQGYIVIAPNRHGVPGFGQKWNEQISGDYGGQNMRDYLTAVDEMKKEPYVDGDRIGAVGASYGGFSVYWLAGHHDKRFAAFIAHAGIFNLEMQYATTEEMWFANWDIGGPFWEKDNVVAQRTYATSPHKYVQNWDTPILMIHGELDFRILASQAMAAFDAAQLRGVPSEMLIYPDENHWVLQPQNALLFHRTFFGWLDRWLKK
What is the function of this protein?
Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.  Prefers Ala and hydrophobic residues except Pro at the P1 position, and has no preference for P2 residues.  Shows high dipeptidyl peptidase activity toward the synthetic substrates Lys-Ala-, Gly-Phe-, Met-Leu-, and Ser-Tyr-methylcoumaryl-7-amide (MCA), and slowly hydrolyzes Val-Tyr-MCA.  Is likely involved in amino acid metabolism and bacterial growth of asaccharolytic P. gingivalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.
What are the official names of this protein?
Dipeptidyl-peptidase 5, DPP5, MER034615.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FUT2_HUMAN
Sequence: MLVVQMPFSFPMAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation (PubMed:7876235, PubMed:8018146, PubMed:12692541).  Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs (By similarity).  Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition (PubMed:22068912, PubMed:21625510, PubMed:24733310).  Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway (PubMed:7876235).
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 2, Alpha(1,2)FT 2, Fucosyltransferase 2, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2, SE2, Secretor blood group alpha-2-fucosyltransferase, Secretor factor, Se, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single- pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: WHIA_CORJK
Sequence: MALSADVKAELNRVLVTRHDVMTAEVASLLRYTAALHLVGKKIVVESEVDSAETARRLTDMVEQLYKIEPEHQIIGAGNLRRRPRHVLRWTEGGMELARRTELIDRVGRPVRGLPRFIIGGTKDQCVAAWRGAFLAHGYITDPGRSSALEVQTPSNEAALALVGAARRIDVTAKTKEARGVNRVVIRDGDSIGRLLMLMGAQDTREVWEKQRRTRENRAKANRLANFDDANLRRSARAAVAAAARVERALEILDNDVPQHLAHAGQLRVEHKEASLEELGRLAEPPMTKDAVAGRIRRLLSMADKRAEELGLPDTHSAVTSELFNDVD
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RL3_BURM9
Sequence: MSLGLVGRKVGMTRIFTAEGDSIPVTVLDVSDNRVTQIKTVETDGYTAVQVAFGSRRASRVTKPLAGHLAKAGVEAGEILKEFRIEADKAAELSNGAVIGPDLFEVGQKVDVQGVSIGKGYAGTIKRYNFGSGRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHMGDETVTVQNLEIARIDADRKLLLVKGAVPGAKGGKVFVTPAVKTRAVKGAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RS12_ANAMM
Sequence: MPTINQLVRRPRRPRESANKAPALQHNPQKRAVCVKVYTTTPKKPNSALRKVARVRIAGYGSEVIAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDAKGVQGRKKARSKYGVKRGV
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: FABPH_BOVIN
Sequence: MVDAFVGTWKLVDSKNFDDYMKSLGVGFATRQVGNMTKPTTIIEVNGDTVIIKTQSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHVQKWNGQETSLVREMVDGKLILTLTHGTAVCTRTYEKQA
What is the function of this protein?
MDGI reversibly inhibits proliferation of mammary carcinoma cells.
What are the official names of this protein?
Fatty acid-binding protein, heart, Fatty acid-binding protein 3, Heart-type fatty acid-binding protein, H-FABP, Mammary-derived growth inhibitor, MDGI.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion matrix.