PharMolix/UniProtQA huggingface dataset:
Protein: DEFB2_SHEEP
Sequence: MRLHHLLLVLFFVVLSAGSGFTHGVTDSLSCRWKKGICVLTRCPGTMRQIGTCFGPPVKCCRLK
What is the function of this protein?
Has bactericidal activity.
What are the official names of this protein?
Beta-defensin 2, BD-2, sBD2.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NFI_YERP3
Sequence: MFDTKALQAEQRQRASEISLHDGIDNQFVRFIAGADVGFEQHGEITRAAIAILRYPSLALVEYQVARVATSLPYIPGLLSFREYPALLAAWAQLQQRPDLILVDGQGIAHPRRLGVASHFGLLVDVPTIGVAKSRLCGDFLPLHQDVGAVQPLFDNDEQLGWVWRSKIRCNPLFISPGHRVSVGSALAWVQRCMAGYRLPEPTRWADAIASNRPQFQRWLRKNPDFLGKRRDMI
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_STRPB
Sequence: MDKIIKSIAQSGSFRAYVLDSTETVALAQEKHNTLSSSTVALGRTLIANQILAANQKGDSRITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATGEVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNVLLDENDKVKVAGGFMVQVLPGASEEEVARYEKRLQEMPAISHLLASKNHVDALLEAIYGDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQFNESDLEAIINDKA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_NOSP7
Sequence: MSENLRSQVVTQGVQRSPNRAMLRAVGFKDEDFNKAIVGIANGYSTITPCNMGINQLAQRAEAGIKTAGAMPQIFGTITISDGISMGTEGMKYSLVSREVIADSIETACTGQSMDGVLAIGGCDKNMPGAMLAIARMNIPAIFVYGGTIKPGHYNGRDLTVVSSFEAVGQYSAGKIDDKELLEVESRACPGAGSCGGMFTANTMSSAFEAMGMSLPYSSTMAAEDAEKADSTEKSAFVLVEAIKKQILPRQIITRKSIENAISVIMAVGGSTNAVLHFLAIARAANVELTLDDFETIRARVPVLCDLKPSGKYVATDLHKAGGIPQVMKMLLAHGLLHGDSLTISGQTIAEILADIPEEPSANQDVIRAWNNPMYAQGHLAILRGNLATEGAVAKITGVKKPVITGPARVFESEEASLDAILAGKIQAGDILVIRYEGPKGGPGMREMLAPTSAIIGAGLGDAVGLITDGRFSGGTYGMVVGHVAPEAAVGGAIALVEEGDSITIDAPARLLQLNISEEELARRRANWQPPAPRYTKGVLAKYAKLVSSSSIGAVTDLDLF
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SCP41_VERDV
Sequence: MRTETASLLLLAALSVAEELTPNDVPLACANMCGPIVELSYKCDVDGTDELRKLKRRKLFSPQQQQQQQQQQQQSAPKAKRQADPEPQAPAPVPSSTNNQQAADVIFIPGSIGKFKTIPTPLPPADTGVPSMAVTPAAPAPTLPVLDLRPTTTPTNLNPNLPILATPILPSVPASTPLATASSTQVPLPVGNEADAGDGVDAGPAPSNSLNGNVGDMVDDAGNLWPGQKGRQAASDLETACICSNTSFNVRRVAGLCGDCLEQVSGDQGPMRAILASCNFTTERYEPEKESLVANVRVEATKPSFTQTAAASYSWRVSGPTWAVVVGAGMLLGMGW
What is the function of this protein?
Effector that binds transcription regulators in the host plant to suppress the host's innate immune response (PubMed:29757140).  Inhibits the host plant transcription regulators CBP60G and SARD1 (PubMed:29757140).
What are the official names of this protein?
Effector SCP41, Cysteine-containing protein 41, VdSCP41.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: CCMF_PSEAE
Sequence: MIPELGHLALILALCLALVQSSLPLVGAWRGDRQWMSLARPAAWGQFAFLAFAFGCLTWAFLRDDFSVAYVAGNSNSALPWYYKFSAVWGAHEGSLLLWALILGGWTFAVSIFSRQLPEVMLARVLAVMGMISTGFLLFLIITSNPFSRLLPQTPMDGNDLNPLLQDVGLIVHPPMLYMGYVGFSVAFAFAIAALLGGRLDAAWARWSRPWTLVAWAFLGIGIVLGSWWAYYELGWGGWWFWDPVENASFMPWLVGTALIHSLAVTEKRGVFKSWTVLLAIAAFSLSLLGTFLVRSGVLTSVHAFASDPERGVFILAFLLLVVGGSLTLFALRAPVVKSQVGFALWSRETLLLLNNLVLVVAASMILLGTLYPLLLDALSGAKLSVGPPYFNAMFLPLMAALMAALAVGVLVRWKDTPSRWLLGMLTPVLAASAVLAAAGSMYFGDFNWAVLAVFLLSAWVVLAGFRDFLDKTRHKGVLAGARSLTRSYWGMQLAHLGIAVCAIGIVLSSQYSAQRDLRMSPGDTVELGGYHFLFDGAKHHEGPNYTSDKGSIHVSRDGKEIATLHPEKRLYTVQSSMMTEAGIDAGFTRDLYVALGEPLENGAWAVRVHVKPFVRWIWFGGLLMGLGGALAALDRRYRVKVKTRVREALGLAGQGA
What is the function of this protein?
Required for the biogenesis of c-type cytochromes.  Possible subunit of a heme lyase (By similarity).
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmF.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IFNB_RAT
Sequence: MANRWTLHIAFLLCFSTTALSIDYKQLQFRQSTSIRTCQKLLRQLNGRLNLSYRTDFKIPMEVMHPSQMEKSYTAFAIQVMLQNVFLVFRSNFSSTGWNETIVESLLDELHQQTELLEIILKEKQEERLTWVTSTTTLGLKSYYWRVQRYLKDKKYNSYAWMVVRAEVFRNFSIILRLNRNFQN
What is the function of this protein?
Type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli.  Signals via binding to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptor, activating the canonical Jak-STAT signaling pathway resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response, such as antiviral proteins, regulators of cell proliferation and differentiation, and immunoregulatory proteins (By similarity).  Signals mostly via binding to a IFNAR1-IFNAR2 heterodimeric receptor, but can also function with IFNAR1 alone and independently of Jak-STAT pathways.  Elicits a wide variety of responses, including antiviral and antibacterial activities, and can regulate the development of B-cells, myelopoiesis and lipopolysaccharide (LPS)-inducible production of tumor necrosis factor.  Plays a role in neuronal homeostasis by regulating dopamine turnover and protecting dopaminergic neurons: acts by promoting neuronal autophagy and alpha-synuclein clearance, thereby preventing dopaminergic neuron loss.  IFNB1 is more potent than interferon-alpha (IFN-alpha) in inducing the apoptotic and antiproliferative pathways required for control of tumor cell growth (By similarity).
What are the official names of this protein?
Interferon beta, IFN-beta.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: TULP1_AEDAE
Sequence: MEAYIRQKRATPGMVQASDMQLVRPMSAVNRNGREVHAYDGPMQFMMSPNNPDQILTSTGNASVTTTPTSPYSDAPLEKLTPSSQDSEDEESTPVDILPSSNSFDSTRHSADHLLTHSAPISPALMNNNGGSHHDSSSGKSVEHSSPQASGHNDTEGDVVGPIEQWVTQPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKKVFCLAGRKRKKSKTSNYIISCDPTDLSRQADGFVGKLRSNVFGTTFFVYDSGKKEDHGNPRLDLAVVIYDTNILGFKGPRNMTVLLPGMTEDDQRVKISSADSQQGLLDSWKSKNMDNVVELHNKTPIWNDETQSYVLNFHGRVTQASVKNFQLVHDSDPDYIVMQFGRTSDDIFTMDFRYPLCAFQAFAIALSSFDGKLACE
What are the official names of this protein?
Protein king tubby 1.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LSPA_PORGI
Sequence: MASFLSRLPQGKVVAALIVLLLVVDQVIKIWVKTTMVLGQSHVVAPWFQIHFVENPGMAFGIELGSKLFLSLFRIVAMGFCIYLLAKLVRKREHTLAFLSCLSLIIAGGIGNIIDSIFYGVIFSGSHGQIAQLFPSGGGYETWFHGRVVDMFYFPLIEGVFPSWLPFWGGEEFVFFHPVFNFADSCISIGLILLLVCYPRTVSLLLDGKKTLPEGTTEDSEPTKRE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IHFB_GLUDA
Sequence: MTKSELIAELAAANPHLLSRDVELIVQTIFSEISAALARGDRVELRGFGAFTVKKRDARTGRNPRTGEMVAVDEKVVPFFKAGKELRERVNNGAPAED
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: UVRC_THEAB
Sequence: MLDKSVLYNVSEKPGVYIFKNGSEYIYIGKAKNLKRRLNSHFSLKEEKSRLIVEESNSLEVIIVKNEKEALLLEATLIFKHKPKYNIMLKEGERYPYIRISDDEYPYVEVTRSRKSSGIFFGPFTNITFTRLLLEILQKIFGVRTCKKDLSKIKKPCIEYHLKTCLAPCKFENKNIYMSAINNLKKVLSGDFEFVKDYIEQKMNYHSKMLDFENAAKYRDLLLSFEKLLNTQGVILNDKRCVDYIAYSKKVFLVLKVRGGVLLSKLFYEANLSFEEFLYQFYYGMKSDLPTKIVTFESSNLNKIEFDIPINVSLDDSDRYLLEIAYENLKEHFKAKRLRRDTLKKIKEILGLKKIPYRIEGTDISHRNGKFTVASLVVFENGVPKPEEYRRYKLGDILDDFESIRMFIRKRYTKHEAPDLIFVDGGRGQVNAAIEAFNELGLDVDVVGIAKKEEIIVTKNKEFKLKENDEVLRTLISIRDETHRVANSFSGSLKLKNYTLSKLDDIPGIGPKRKKILLKKYKSIENIKNAPLEELSKIVGNKIALRLKEYL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNU_HUMAN
Sequence: MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEKRGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.  Has a preference for the L-3-hydroxy form.  Also has cysteine-conjugate-beta-lyase activity.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: END4_VIBVY
Sequence: MTNSKNRFGNKFIGAHVSAAGGVDNAPLRAREIGANAFALFTKNQRQWVAKPLEEKTISAFKANCALLGFSPQQILPHDSYLINLGAPEAEKLEKSRLAFIDEMERCQLLGLNLLNFHPGSHLEKISEKACLYLIAESINLAHQAVPDVVAVIENTAGQGSNLGWRFEHLAEIIEQVEDKSRVGVCLDTCHTFAAGYDLRTPEACEATFAEFERVVGMHYLRAMHINDSKVKLASKVDRHHALGKGEIGWDCFEYIAKDSRFDSIPLILETIEPELWPQEIEQLRKYHLSSIA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: FBD10_ARATH
Sequence: MDRISNLSDDLLLKIVSSLPTKDVVVTMLLSKRWKFLWMMVPKLRFDDEFELEPSYYGRFLKYVDKSMVLNRAQVLETVKFNVGPCCSSEDIATWIRIGMVRNMRELEISHCEGYFREHRSIKLPKSLYTYEKLEVLKLASTVVLNVPIDVCFPSLKSLHLVCVEYKTKKSHRRLLSGCPVLEELVLDKSYNSFHVRSFYVEIPTLQSLSILDTSGELYGDFTFVVNAPALKYFNFVDFYGDLCLRDNMPEVVDVNIKVIYRNPKKLLGPLKSVKRLSLCLSPSTTLHNHMEFYQLVHLELCGDALMWWDLLTWMLQSSPKLQVLKIYECKCEEHDYLDDPIEEHWEEPSSVPQCLLFHLNIFEWKYYNAGDEEKKVVAYILKNARQLKTATFSAASYLYPKEERSRELNELVYMARASSSCQLLLD
What are the official names of this protein?
Putative FBD-associated F-box protein At3g50710.
Protein: VP4_ROTEL
Sequence: MASLIYRQLLGNSYAVDLSDETQEIGASRNQNVTVNPGPFAQTNYAPVSWGPGEVRDSTTVEPLLDGPYQPTTFNPPVDYWMLLAPTDRGVVVEGTNNTNRWLAIILVEPDVPTEERTYTLFGQQAQITVANDSQLKWKFIVVSKQTLDGAYAQYGPLLSATKLYAVMKHSGRIYTYSGETPNATTAYYSTTNYDTVNMKAYCHFYIIPRTQESKCTEYINTGLPPIQNTRNVIPVSITSRDIQYTRAQVNEDILISKASLWKEMQYNRDIIIRFQIANSIVKSGGLGYKWSEISFKPANYQYSYIRDDEEVTSATTCSVNGVNEFSYSGGSLPTDFAVSKYEVIKENSFVYVDYWDDSQAFRNMVYVRSLAANLNSVMCTGGDFSFALPVGHYPVMTGGAVTLHSAGVTLSTQFTDFVSLNSLRFRFSLSVEEPPFSIIRTRVSGLYGLPATKPNNSQEYYEIAGRFSLISLVPSNDDYQTPIMNSVTVRQDLERQLSELRDEFNSLSQQIAMSQLIDLALLPLDMFSMFSGIKSTIDAAKSMVTNVMKKFKKSSLANSVSTLTNSLSDAASSVSRSSSIRSIGSTASAWTDVSITASDVSTATNSIATQTSTISKRLRLKEMATQTDGMNFDDISAEMLKTKIDKSTQITADTLPEMITEASEKFIPNRTYRIINNDEVFETSIDGKYFAYRVDTFEEIPFDVQKFADLVTDSPVISAIIDFKTLKKLNDNYGITKEQAFNLLRSDPKVLREFINQNNPIIKNRIENLIMQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: GATC_DICDI
Sequence: MLSIPEDKVEQYCDDLGGFLNSVESIQSVNTENVRPLHSILEDTQLTLHFEQTTVNQDHEHILDHSNNVQGGFFTVPKQISSHTNSQKSNKNNSIDDEF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial, Glu-AdT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL15_PYRAE
Sequence: MVRRFKRGTKYRRGSRTHGWGRVGQHRKSGGSGGKGMVGFHKHKWSLVMKYGESGTGWPFYGKHGFKQPPPISIEWRPINVGTLAELVKELKAEGKVREEGGKYVINLLELGFNKLLGGGTIDLPVIVYTPIASRTAVEKIEKAGGEVRIIHVIHR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: LGUL_NEIMA
Sequence: MRLLHTMLRVGNLEKSLDFYQNVLGMKLLRRKDYPEGRFTLAFVGYGDETDSTVLELTHNWDTERYDLGNAYGHIAVEVDDAYEACERVKRQGGNVVREAGPMKHGTTVIAFVEDPDGYKIEFIQKKSGDDSVAYQTA
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
What are the official names of this protein?
Lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: IF2A_SULIN
Sequence: MIYSRSRLPSEGEILIATVKQVFDYGSYVTLDEYGGLQAFLPWSEVSSKWVKNIRDVLKENRKVVVKVIRVDRRKGTVDVSLKKVTDDERRKKNLQWKKIQRLDKILELVSQQLKLSEKDAWEQVAWKLEAKYGDPISAIERAVKEGEKILIDAGVPEIWIKPLLEEAAKHTEEKKVKMSGLITVKTSEPLGVQKIKEVMSKALENIEQDYESILNVKIYTIGAPRYRVDVVGTNPKDASEALNQIISNLIKIGKEENVDISVVKK
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit alpha, aIF2-alpha, eIF-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
Protein: SYY_STRGG
Sequence: MTDIVDELKWRGLFAQSTDEDALRKALADGPVTFYCGFDPTAASLHVGHLVQVLTMRRLQQAGLKPLALVGGATGQIGDPRPTAERTLNDPETIAAWVQRLRGQIEPFLTFEGPNAATMVNNLDWTAGMSAIEFLRDIGKHFRVNKMLTKDSVARRLESQEGISYTEFSYQLLQGMDFLELYRRHGCTLQQGGSDQWGNLTAGIDLIHRLEPGAVVHALATPLMTKADGTKFGKSESGAVWLDPEMTTPYAFYQFWLNVDDRDVSRYLRILSFKSREELAELEKLTEERPQARNAQRALAEELTTLVHGGEQCAAVIAASKALFGQGDLAELDEATLSAALSEVPHATVAELGPLVDLLVEVGLAPSKSGARRTVKEGGAYVNNVKVVDGEVAPDAGELLHGRWLVLRRGKKNLAAVEVGPVG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_PSEPG
Sequence: MLQPKRTKFRKQMTGHNRGLALRGSKVSFGEFALKAVARGRLTARQIESARRALTRHVKRGGKIWIRVFPDKPISKKPLEVRMGKGKGSVEYWVAQIQPGKVLYEIEGVSEELAREAFALAAAKLPLATSFVKRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MNME_TREPS
Sequence: MRAHEYALDDDIVAIATALSPAALGIVRTSGSSSIERVASFFSRAQALTRARAHTFLHGWILDGKTRVDEVVLLVYRAPHSFTGEHAVEIICHGGVRTVQAVYRLCLAQGFRAAQRGEFSFRSFFHGKRDLTRIEAIQSLVDARTCAAQQQAVLHLSGALQQEIAALTRALLAFSATLQGEIEYPEDEETRVHDIDMRELEPLVERLRRLRACWQERALQRTGVRIVLGGCPNAGKSSLFNALLGQDRAIVSSVPGTTRDWLEADLDLSGIPVRLCDTAGLRVTDNPIEAQGVVRSEQLLQGADCVFYIINGRAGVQAADCAFLSDCAVPLVVVVTHNDLMSMSERIQVCQAVQPFISAPVLSCARSQDARGAGEQCLAGGKNGEVRDRAPRAFVCVSAKTHAGLDALRAQTLHLLHGGQVPYEELSLGSERQYVLVDAAVQALEHAQEAYARGFGLDAVVHDLEEALYHCGALTGEVHSEDILDALFEKLCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UDG_RHIME
Sequence: MKITMIGAGYVGLVSGVCFADFGHDVVCVDKDEGKISALKKGQIPIFEPGLDHLVASNVASGRLNFTDDLKTAVAASDVVFIAVGTPSRRGDGHADLSYVYAAAREIAANLQGFTVVVTKSTVPVGTGDEVERIIRETNPAADVTVVSNPEFLREGAAIEDFKRPDRIVIGVDGSDGRAREVMTEVYRPLYLNQSPLVFTTRRTSELIKYAGNAFLAMKITFINEIADLCEKVGANVQDVARGIGLDGRIGSKFLHAGPGYGGSCFPKDTLALVKTAQDHDTPVRLVETTVAVNDNRKRAMGRKVIAAAGGDIRGSKIAVLGLTFKPNTDDMRDSPAIAVVQALQDAGARVTGYDPEGMENARKLIEGLDCARDPYEAAAEADALVIITEWNEFRALDFDRLKSTMKTPLLVDLRNIYRKDEVAKHGFRYASIGRPD
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: YEBV_ECOLI
Sequence: MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAWDAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA
What are the official names of this protein?
Uncharacterized protein YebV.
Protein: ZAT2_ARATH
Sequence: MSNTSNSDPNSDIPFASSNVTLPSYNQNPRRKRTKLTNNEVGSSSSSPRPKPVTQPDPDASQIARPCTECGKQFGSLKALFGHMRCHPERQWRGINPPSNFKRRINSNAASSSSSWDPSEEEHNIASCLLMMANGDVPTRSSEVEERFECDGCKKVFGSHQALGGHRATHKDVKGCFANKNITEDPPPPPPQEIVDQDKGKSVKLVSGMNHRCNICSRVFSSGQALGGHMRCHWEKDQEENQVRGIDLNVPAATSSDTTLGCSLDLRLGL
What is the function of this protein?
Mediates the regulation of male germ cell division by DUO1.
What are the official names of this protein?
Zinc finger protein ZAT2, Protein DUO1-ACTIVATED ZINC FINGER 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: KHPA_CLOPE
Sequence: MKELVEIIAKSLVDKPEDVHVNEVLGEESIILELKVSPEDMGKVIGKQGRIAKAIRTVVKAAAIKENKKVVVEII
What is the function of this protein?
A probable RNA chaperone.  Forms a complex with KhpB which binds to cellular RNA and controls its expression.  Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
What are the official names of this protein?
RNA-binding protein KhpA, KH-domain protein A.
What is the protein family that this protein belongs to?
Belongs to the KhpA RNA-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_LACE2
Sequence: MRYITIALAKGRLAKKAMEIFEQIGIPCEEMKDEKTRKLIFTNEELGFRFFLSKPSDVPTYVEYGAADIGIVGKDTILEEGRSLYEVYDLQMGKCRMCVCGPESAREKLQHHELIRVASKYPNIAKDYFNNIKHQTVEIIKLNGSVELAPIVGLAEVIVDIVETGATLRENGLEVLEEVCPLSARMVVNQVSMKMEQERINKLINDVKKYIETQGR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_MYCMM
Sequence: MAELNVEIVAVDRKIWSGAGTFLFTRTTVGEIGILPNHIPLVAQLVDDAMVRVERDGDKDLRIAVDGGFMSVTDAGVSILAESAEFESEIDEAVARQDSESDDPRTAARGRARLRAVGAID
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYRH_ROSDO
Sequence: MTTPEPQAAFKRVMLKISGEALMGDQGFGLHPPTVERVAREVQSVHALGVEICMVIGGGNIFRGLQGSAQGMERTTADYMGMLATVMNALAMQSALEGLGIHTRVISAITMNEVAEPYIRRRAVRHLEKKRVCIFAAGTGNPYFTTDTAATLRANEMSCEAIFKGTKVDGVYDKDPAKFADAKRYDTVTYDDVLAKRLGVMDASAIALARDNNLPIIVFSLDEPGGFRGILAGEGTYTRVQD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.