PharMolix/UniProtQA huggingface dataset:
Protein: ADIC_ECOLI
Sequence: MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIYGWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNIAMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALIPIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILMTIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTTIAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD
What is the function of this protein?
Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach (Probable).  Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons (PubMed:12867448, PubMed:14594828, PubMed:19578361, PubMed:21368142).  Probably undergoes several conformational states in order to translocate the substrate across the membrane; keeps the substrate accessible to only 1 side of the membrane at a time by opening and closing 3 membrane-internal gates (Probable).
What are the official names of this protein?
Arginine/agmatine antiporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSTT3_MOUSE
Sequence: MGLELYLDLMSQPCRAVYIFAKKNGIPFQLRTIELLKGQQYTDSFAQVNPLRKVPALKDGDFVLAESVAILLYLSRKYKAPDHWYPQDLQTRARVDEYLAWQHTALRSCCTRAMWQKMMFPVFLGQPVPPEMLASTLAELDGCLQVLEDKFLRNQAFLTGSHISVADLVAITELMHPVSAGCKIFESRPKLAAWRQRVEAEVGESLFQEAHEVVLKAKDMPPLMDPALKEKLKLSVQCLLH
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Shows high activity towards 4-nitrobenzyl chloride (4-NBC).  Also has lower activity towards 1,2-epoxy-3-(p-nitrophenoxy)propane (EPNP), cumene hydroperoxide, 1-chloro-2,4-dinitrobenzene (CDNB), 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl), and ethacrynic acid.
What are the official names of this protein?
Glutathione S-transferase theta-3.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPP_STAAU
Sequence: MKRNFPKLIALSLIFSLSITPIANAESNSNIKAKDKRHVQVNVEDKSVPTDVRNLAQKDYLSYVTSLDKIYNKEKASYTLGEPFKIYKFNKKSDGNYYFPVLNTEGNIDYIVTISPKVTKDSSSSSKYTINVSSFLSKALNEYKDQQITILTNSKGYYVVTQNHKAKLVLKTPRLEDKKAKKTESIPTGNNVTQLKQKASVTMPTSQFKSNNYTYNEQYVNKLENFKIRETQGNNGWCAGYTMSALLNATYNTNKYHAEAVMRFLHPNLQGQQFQFTGLTPREMIYFEQTQGRSPQLLNRMTTYNEVDNLTKNNKGIAILGSRVESRNGMHAGHAMAVVGNAKLNNGQEVIIIWNPWDNGFMTQDAKNNVIPVSNGDHYQWYSSIYGY
What is the function of this protein?
Cysteine protease that plays an important role in the inhibition of host innate immune response.  Cleaves host elastins found in connective tissues, pulmonary surfactant protein A in the lungs, and the chemokine receptor CXCR2 on leukocytes (PubMed:3422637, PubMed:23235402).  Proteolytic cleavage of surfactant protein A impairs bacterial phagocytosis by neutrophils while CXCR2 degradation blocks neutrophil activation and chemotaxis (PubMed:3422637, PubMed:23235402).  Additionally, promotes vascular leakage by activating the plasma kallikerin/kinin system, resulting in hypotension (PubMed:15897280).
What are the official names of this protein?
Staphopain A, Staphylococcal cysteine proteinase A, Staphylopain A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C47 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PADI2_MOUSE
Sequence: MQPPIRENMLRERTVRLQYGSRVEAVYVLGTQLWTDVYSAAPAGAKTFSLKHSEGVKVEVVRDGEAEEVVTNGKQRWALSPSSTLRLSMAQASTEASSDKVTVNYYEEEGSAPIDQAGLFLTAIEISLDVDADRDGEVEKNNPKKASWTWGPEGQGAILLVNCDRDTPWLPKEDCSDEKVYSKQDLQDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRQKLYHVVKYTGGSAELLFFVEGLCFPDESFSGLVSIHVSLLEYMAEGIPLTPIFTDTVMFRIAPWIMTPNILPPVSVFVCCMKDNYLFLKEVKNLVEKTNCELKVCFQYMNRGDRWIQDEIEFGYIEAPHKGFPVVLDSPRDGNLKDFPIKQLLGPDFGYVTREPLFETVTSLDSFGNLEVSPPVTVNGKEYPLGRILIGSSFPLSGGRRMTKVVRDFLQAQQVQAPVELYSDWLTVGHVDEFMTFIPIPGKKEFRLLMASTSACYQLFREKQKAGHGEAVMFKGLGGMSSKRITINKILSNESLTQENQYFQRCLDWNRDILKRELALTEKDIIDLPALFKMDENHQARAFFPNMVNMIVLDKDLGIPKPFGPQVEEECCLETHVRGLLEPLGLACTFIDDISAYHKFLGEVHCGTNVRRKPFTFKWWHMVP
What is the function of this protein?
Catalyzes the deimination of arginine residues of proteins.
What are the official names of this protein?
Protein-arginine deiminase type-2, Peptidylarginine deiminase II, Protein-arginine deiminase type II.
What is the protein family that this protein belongs to?
Belongs to the protein arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_INCNB
Sequence: MLGLTEAEKIKICLQKQVNSSFSLHNGFGGNLYATEEKRMFELVKPKAGASVLNQSTWIGFGDSRTDQSNSAFPRSADVSAKTADKFRSLSGGSLMLSMFGPPGKVDYLYQGCGKHKVFYEGVNWSPHAAIDCYRKNWTDIKLNFQKSIYELASQSHCMSLVNALDKTIPLQVTKGVAKNCNNSFLKNPALYTQEVKPLEQICGKENLAFFTLPTQFGTYECKLHLVASCYFIYDSKEVYNKRGCGNYFQVIYDSSGKVVGGLDNRVSPYTGNSGDTPTMQCDMLQLKPGRYSVRSSPRFLLMPERSYCFDMKEKGPVTAVQSIWGKGRESDYAVDQACLSTPGCMLIQKQKPYIGEADDHHGDQEMRELLSGLDYEARCISQSGWVNETSPFTEEYLLPPKFGRCPLAAKEESIPKIPDGLLIPTSGTDTTVTKPKSRIFGIDDLIIGLLFVAIVEAGIGGYLLGSRKESGGGVTKESAEKGFEKIGNDIQILRSSTNIAIEKLNDRISHDEQAIRDLTLEIENARSEALLGELGIIRALLVGNISIGLQESLWELASEITNRAGDLAVEVSPGCWIIDNNICDQSCQNFIFKFNETAPVPTIPPLDTKIDLQSDPFYWGSSLGLAITAAISLAALVISGIAICRTK
What is the function of this protein?
Binds to the N-acetyl-9-O-acetylneuraminic acid residues on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HEF2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.  Displays a receptor-destroying activity which is a neuraminidate-O-acetyl esterase.  This activity cleaves off any receptor on the cell surface, which would otherwise prevent virions release.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.
What are the official names of this protein?
Hemagglutinin-esterase-fusion glycoprotein, HEF.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: DXS_CLOPE
Sequence: MSEVLQRITDPKEIKDLDEKELEILAEDLREFLIESVSNTGGHFASNLGVIDLTVALFKNFDFSEDRIIWDVGHQSYAYKILTGRKDKFNTLRQYGGLCGFPKRTESEYDFFATGHSSTSLSSAAGMARAQRLLGKDNKVIAVIGDGALTGGMALEALNDIGYRKDNLIIILNDNQMSICKNVGGLATYLNKLRMGVGYNKLKSDIGSTLDTTSLGKRVKNSLSKLKDGIKKIVVPSMYFEDIGLKYFGIVDGHNIRELNEVLSIAKNIKGPVIIHTVTKKGKGYELAEKNPNKYHGVSPFDLGEGVISKFSSRNYSSTFGEEMIKLAKNDDKVVAITAAMPDGTGLKDFREEFPDRFFDVGIAEQHAVTLAAGMAAEGLKPFFAVYSTFLQRAYDQVLHDVCIQKLPVTLCLDRAGLVGEDGETHQGIFDISFLSPMPNMTIVAPKCIDEMEVILKWASNFNAPLAIRYPRGGDIDVNLKPLSKIEYGKWEKVQEGEKIAIVATGKMVQHAMIAAQKIKEEKNIDILIINATFIKPIDKELLNSLSKDGFKIVTIEDNIKKGGFGEGVLEYLNEIGHKEKIVTLAFNDKFIEHGKPDILYKINGLDAEGIKNTLIELL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: LIPB_SALTO
Sequence: MTTTTPDLTIVRAGTLGYEAAWEEQRRLHESVVADERGDAVLLLEHPSVYTAGKRTEPWDRPMDGTPVIDVDRGGKITWHGPGQLVGYPILRLPNPVDVVAYVRRVEQMLIDVCAEFGLVAGRIEGRSGVWVPADDRGPARKVAAIGIRVARGVTLHGFSLNCDCDLTYYDRIVPCGISDAGVTSLAAELGRPVTVADALPVVERHLPTLIEP
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTE1_KLULA
Sequence: MWLTSYVLPRLKNILLLQFHITLPLNYLVLLLLSTVIITYLFLRTRILSNYSQLKDDVSDENNINRKDYMDASSASFLLNREKHKGFTSYLDEFLSAIKIFGYLEKPVFHELTKSMKTEKLQEGEIVLLDDSVGFTIVVEGTLEILHKMDNRHSNPSGDAAANATAFEPPSNDDGYLINGEKFQLLNIVKTGNPLSSLVSIMKLFSNRSTHLNEGTHPSTTNNTPGPGSPNLTGEINSFLDSTLPAKFGSADSANGNHPISPMELESTFDNLSEASENDRSAKIPDIIARAASDCTIAIIPSSSFQRLLVKYPRSASHIIQMILTKLYRVTFKTAHTYLGLTNEIIFTEFQSINKDNLKLPEYFRRSIISYFTNRQDDTGSSASTIQKRPQLHRRDSNNSLNYGSRHVVLNSRDQYNPGDLLSNVPLPRLNPQQRNDLSNTNSSSTLSRADYRPIILNNFSSSQFEETEVSSWRLALVEIIFQQLGITKDTIEPPISDDFSLHDHSLDEKGLVRRSSYSSFTSLSSSIATHSSNHLVTFLPRESQQFSRLNRTGGKMASHSKRLNGSSRSNSRTDRSESFDHFRNENLGGDNQFSDFESVKEDFSKCIKILKFEEGETILCQNSNPQGIYYLVSGEVDVISETKDGNTDESYERTLYTATEGYILGYLSSILGCKSLVTLKVSKGPAYLGLIPYNDLERLCDKYFMIYLKLSEILTNSLSPNLLRLDYFLEWIQLDSSETLFNQGDPANGVYLVLNGRLRQLFYEDADSDIVTQMAELSKGESFGEVEVLTAIHRLNTVVAIRDTELARIPRTLFEFLAVEHPSIMIHVSRMVAKKAMLMNFKSGIGFSGSQPITKLIGDETAMQKRYDFNLNIKSNKSSKKNELISNTVNYKTLTLLPITEGLPVEEFAYKLINALRQCGKTTIGLNQRTTLSHLGRHAFNKLSKLKQSGYFAELEELYEIVVYIADTPVSSSWTQTCISQGDCILLLADATCDPKIGEFERLLLKSKTTARTDLILLHPERYVVPGSTSKWLKNRMWIQSHHHIQFTPMEKVAEPDPIPNIKPLSQLVEKFKENTKKTQENFVKFLPDSIKTTVETLSGKYIDPKPNPKFYTSVDPIKNDFLRLARTLSGQAVGLVLGGGGARGLSHLGIIKALEEQGIPIDIIGGTSIGSFVGGLYAMDYDLVPIYGRVKKFAGRVGSLWRMLSDLTWPVTSYTTGHEFNRGIWKSFRDYRIEDFWISYYCNSTNITESVQEIHSSGFAWRYIRASMSLAGLLPPIVDNGNMLLDGGYVDNLPVTEMTQRGCKIVFAVDVGSVDDRTPMSYGDSLNGFWIVLNRWNPFSKHPNIPNMAEIQMRLGYVASVNALERAKSTPGVVYIRPPIENYATLDFGKFEEIYQVGYAYGHDFLQHLQEKNELPPIAGTTTSAYADKENMLQRRNSI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase NTE1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: UREE_UREPA
Sequence: MTVFKEILDNIANIKNVESYQIENIHLTSDDVLKRVIIISSDQNVEYGIRLEEDKKLMDGDILYKDDYKLVVIRLELSDVLIITAHTIGEMAKIAHNLGNRHMPAQFTETQMIVPYDYLVEEYLQDNKALYERKKIKLKEAFKHCSDAK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPSP_MOUSE
Sequence: MRFFPILCLVLFISHGVASRRHSHSKKKKAKESSVGAVGPPSSKDFAFRLYRALVSESPGQNVFFSPLSVSMSLGMLSLGAGLKTKTQILDGLGLSLQQGQEDKLHKGFQQLLQRFRQPSDGLQLSLGSALFKDPAVHIRDDFLSAMKTLYMSDTFSTNFGNPEIAKKQINNYVAKQTKGKIVDFIKDLDSTHVMIVVNYIFFKAKWQTAFSETNTHKMDFHVTPKRTTQVPMMNREDGYSYYLDQNISCTVVGIPYQGNAIALFILPSEGKMKQVEDGLDERTLRNWLKMFTKRRLDLYLPKFSIEATYKLENVLPKLGIQDVFTTHADLSGITDHTNIKLSEMVHKSMMEVEESGTTAAAITGAIFTFRSARPSSLKIEFTRPFLLTLMEDSHILFVGKVTRP
What is the function of this protein?
Heparin-dependent serine protease inhibitor acting in body fluids and secretions.  Inactivates serine proteases by binding irreversibly to their serine activation site.  Involved in the regulation of intravascular and extravascular proteolytic activities.  Plays hemostatic roles in the blood plasma.  Acts as a procoagulant and pro-inflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin complex.  Acts as an anticoagulant factor by inhibiting blood coagulation factors like prothrombin, factor XI, factor Xa, plasma kallikrein and fibrinolytic enzymes such as tissue- and urinary-type plasminogen activators.  In seminal plasma, inactivates several serine proteases implicated in the reproductive system.  Inhibits the serpin acrosin; indirectly protects component of the male genital tract from being degraded by excessive released acrosin.  Inhibits tissue- and urinary-type plasminogen activator, prostate-specific antigen and kallikrein activities; has a control on the sperm motility and fertilization.  Inhibits the activated protein C-catalyzed degradation of SEMG1 and SEMG2; regulates the degradation of semenogelin during the process of transfer of spermatozoa from the male reproductive tract into the female tract.  In urine, inhibits urinary-type plasminogen activator and kallikrein activities.  Inactivates membrane-anchored serine proteases activities such as MPRSS7 and TMPRSS11E.  Inhibits urinary-type plasminogen activator-dependent tumor cell invasion and metastasis.  May also play a non-inhibitory role in seminal plasma and urine as a hydrophobic hormone carrier by its binding to retinoic acid (By similarity).
What are the official names of this protein?
Plasma serine protease inhibitor, Plasminogen activator inhibitor 3, PAI-3, PAI3, Protein C inhibitor, PCI, Serpin A5.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Note=Localized on the plasma membrane overlying the acrosomal head of spermatozoa of ependymal spermatozoa and ejaculated sperm. Localized at the equatorial segment of acrosome-reacted spermatozoa. Localized in alpha granules in resting platelets and on the external plasma membrane and within the surface-connected cannalicular system in activated platelets (By similarity).
Protein: CYNS_SULTO
Sequence: MIDKKELREISLKKKREKRLTWEEIGKYLGRDKVYAAMLLYGYAQATEEEADKIITLLDLPKELKPAFLDAPMRTPAQPWPPTDPFIYRLYEGVLLYGPVIKDVAHELFGDGIMSMIDVKIYVDKVIENNYPRMVLTFNGKWLYYSKW
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: KCY_META3
Sequence: MIITIGGLPGTGTTTIAKLISEKYNLNHVCAGFIFRDMAKEMGMGLQEFSKYAEENPNIDHEIDRKQVELAKEGNIVLEGRLATWMLKKNSVEPTISIWLRAPSMVRCERISERECEDINTALNKMINRENSEKKRYKELYDINIDDLSIYDIIINSSAWNIEGVFSIIDRAIANKSK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORTL_BPPHC
Sequence: MGFWSALFGRGHSPALDGIEARAWEPYDPSIYNLGAVAASGETVTPHDALQVSAVFASVRLLSETIATLPLSTYSKRGGSRKEIVTPEWLDYPNAEPGGMGRIDILSQTVLSLLLQGNAFLAVRWQGPNIVGLDVLDPTKIHVHMVMVDGLRRKVFEAYDIDADGNEVLLGWFTPRDVLHIPGMMLPGDFVGCSPISYARESIGLALAAQKYGSKFFANGAMPGAVVEVPGTMSEEGLARAREAWRAANSGVDNAHRVALLTEGAKFSKVAMSPDEAQFLQTRQFQVPEIARIFGVPPHLISDATNSTSWGSGLAEQNIAFTMFSLRPWLERIEAGFNRLLFAETADRFRFVKFNLDEIKRGAPKERMELWSLGLQNGIYSIDEVRAAEDMTPLPDGLGEKYRVPLNLGEVGEEPEPEPAPAPPAIEPPAEEPDEEPEPEGKPDDEGATEEDDEDDA
What is the function of this protein?
Forms the portal vertex of the capsid.  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.  Binds to the terminase subunits to form the packaging machine.
What are the official names of this protein?
Probable portal protein.
What is the protein family that this protein belongs to?
Belongs to the phage portal family.
What are the subcellular locations of this protein?
Virion.
Protein: SYI_ONYPE
Sequence: MTTNYKTTLLMPKTDFPMKGNLGKNEINIQKHWQKLDLYQKKLQQNQDNNPFILHDGPPYANGNIHMGHALNKILKDFIVRFRSMQGFYTPLIPGWDTHGLPIEAAVLKKTSKNAFTRKPLLDKCQEFALENVNNQKHQFQRLGILGDWQNPYLTLDKTFVSDQVRIFGQMVDKGLIFKALKPIHWSPTLESALAEAELEYHNHQSPSVYVAFSMKKLDIFDNVALVIWTTTPWTLPANVAIAVHPEKEYQLIEVLQKRYLVGTKNIPFLQKVFAWNKENIKVVATFEGKTLEHLTYQNHLVSKFGKIILSQHVLDGEGTGLVHIAPGHGLDDFLVGQKYNLDVVCSIDKKGMMTDVSKYQGLFYTKANEAIISDLEKDHSLLKADVILHSYPHDWRTKKPVISLALPQWFVSIKKIKSLLLEETQKVKWIPRWGELKMTNMITNREDWNISRQRTWGVPIPIFYTETHQPILDLKLINHVADLFEQHGMDIWYEWDVKKLLPENYINPQSPNNLFTKELDIMDVWFDSGTSYSVFKKRNQVLQSDVYLEGSDQYRGWFNSSLITSVATQNQAPYKTVITHGFVFDGEGKKMSKSLGNVIDPLTVAEQKGADIIRLWVANTNYNLDVRINPSILKQVEDLYRKIRNTFRFMLGNLDNFKKDTNYIAFEQRTFIHQAMMLDFEEVLKNVLHSYDTYNFEGVLRHLFPFITNKISAFYLDFAKDILYIEKEDHKERKMIQSTIYDLLLSLLQVLTPIIPHTTSEVYGFFPFAVEKDIYLEKMPQLKARPTSHLLLEYHKFLTLRKNVLQYLEKARQSGLINSSLQAHITLSLTQEEMHALDVLQIKDQLHQLFIVSKVTLQLKDTFDVKVAKASGYACQRCWNVVITKPLTPLCTRCQNILK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAD_CLOTE
Sequence: MSILIENVMIVTMDEEQDVIKEGYILIKEDKIKEVNLGAYLGNKENLYIINGEGRCAIPGLVNAHTHAGMTIFRGYGEGLPLMRWLNEKIWPIESKLKGEHVKIATELAALEMLRSGTTCFNDMYFYEEQVVKVAKEFNIRGIIGVSIMGDSWEHQLKEAIDIDKKIKEDKSGLLDSMIAPHSPYTLSKEALESIGKEAKLQNKNIHIHISETQDEVNIIKEKYNKTPCEFLQSVGIFNSKVAAAHCVYLTDEDMNILKQNGTSVIYNPQSNMKLASGIAKIAEMIDMDINVCLGTDGTSSNNNLNMIEEMETGTILQKLYYKDATKLSAKKALEMATYNGAKALINNKKLGKIKKDYLADIALLDLNKPNMLPVNDIHSNIVFSANGSEIDYVIVNGSVVMEKGEFKHIDEEKVLYNFKEMCKDIFNN
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: VELB_EMENI
Sequence: MYAVEDRAHSGHHPPPLSMDRIPPPSTMYPSSAGPSAMVSPAGQPEPESLSTVHDGRIWSLQVVQQPIRARMCGFGDKDRRPITPPPCIRLIVKDAQTQKEVDINSLDSSFYVVMADLWNADGTHEVNLVKHSATSPSISTAMSSSYPPPPHPTSSDYPASYQTNPYGQPVGQPVGQPVGYAGVGNYYGGSTQLQYQNAYPNPQAQYYQPMYGGMAQPQMPAAQPVTPGPGGMFTRNLIGCLSASAYRLYDTEDKIGVWFVLQDLSVRTEGIFRLKFSFVNVGKSVSDLPQSDIAEVINKGTAPILASTFSEPFQVFSAKKFPGVIESTPLSKVFANQGIKIPIRKDGVKGQGSRGRHSDEDDGLDNEY
What is the function of this protein?
Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (PubMed:18556559, PubMed:23049895).  The velvet complex acts as a global regulator for secondary metabolite gene expression (PubMed:18556559).  Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (PubMed:21152013, PubMed:24391470).  The velB-VosA complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (PubMed:24391470).  The vosA-velB complex binds to the beta-glucan synthase fksA gene promoter in asexual spores for repression (PubMed:25960370).
What are the official names of this protein?
Velvet complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VelB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=VeA increases the nuclear localization of VelB.
Protein: PSB_KINRD
Sequence: MAGRVREVSHSSDQSGRLPAAFLRPGSSSFTDFVREYSPEILPATRTLPAAAALPGGGPGAGEPPHATTIVALVFADGVVMAGDRRATAGPMIAQRDIQKVFQTDEHSCAGIAGTAGLAVEMIRLFQVELEHFEKLEGTLMSFEGKANRLSTMIRANLGMAMQGLAVVPLFAGYDLDAGRGRIVGYDITGGRSEEHDHHTVGSGSLFARGSLKKLYRPGMSEAETVRVALEALWDAADDDSATGGPDLLRKIWPVVGVTTAEGYRRVPDAELEPVVEAVVAGRRGNPGGNPGISAVHGDGGN
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_PASMU
Sequence: MATKEEKNKALAAALGQIEKQFGKGSIMKLGDTQALDVEAVSTGSLSLDVALGIGGLPMGRIVEIFGPESSGKTTLTLSVIAQAQKEGKTCAFIDAEHALDPIYAAKLGVNVNELLVSQPDNGEQALEICDALVRSGAVDVIIVDSVAALTPKAEIEGEMGDSHMGLQARLMSQALRKLTGQIKNSNCLVVFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGEEVIGNETRVKVVKNKVAAPFRQVDFQILYGQGISKTGELIELGVKHKLVDKAGAWYAYNGEKIGQGKANAMKWLEEHPEEALALETKLRNELLANPEKVLAADIAEKNESSTGLEADY
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHA_RICPR
Sequence: MTKAYNIIHHKFDVVVVGAGGAGLRSAFGMAKEGLNTACITKIFPTRSHTVAAQGGISAALGNMGEDDWRWHMYDTVKGSDWLGDQDAIEYMCKNAPDAILELEHYGVPFSRTVDGKIYQRPFGGMTTEYGKGKAAQRTCAAADRTGHAILHTLYQQSLKHKVQFFIEYFAIDLLMEDGECRGVVAWNLDDGSLHCFRAHNVVLATGGYGRAYFSATSAHTCTGDGGGMVIRAGLPLQDMEFVQFHPTGIYSAGCLITEGARGEGGYLVNANGERFMERYAPAAKDLASRDVVSRAMTIEIREGRGVGEHKDHVFLHLNHLSPEILHRRLPGISETAKIFAGVDVTKDPIPVLPTVHYNMGGIPTNYQGQVIIKDGKNHNSIVNGIMAIGEAACVSVHGANRLGSNSLLDLVVFGRSSALKAAELIKPASPHKPLQKETLEKIINRFDKVRYANGNILVADLRLKMQRTMQSHVSVFRTQKLLDEGVGMISEIRNRYKDIKINDKSLIWNSDLVEALELDNLLDQALVTVCSAAARKESRGAHAREDYPDRNDRDWIKHTLSSIDDSGKVVLDYKPVTLTTLTDAISAIPPVKRVY
What are the official names of this protein?
Succinate dehydrogenase flavoprotein subunit.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YVAS_VACCW
Sequence: MSVISNPSKYKQSNTNKHMLEFLYSFFLCIPKLPNGSGTLCSSTRTISESNTIDVAFLNAFGMYSLR
What are the official names of this protein?
Uncharacterized 7.5 kDa protein.