PharMolix/UniProtQA huggingface dataset:
Protein: B1V_SICPE
Sequence: MGHMVDDLKMVDYYVGKGANGLELDVTFNSNGVAEYTFHGVPCDCFRSCTRYENINTYLDYVRQLTTPGDPKFQEKLIFLIMDLKLKNSPSSYAQFNAGINIADKLSQYYWKDDGKARAYFLISVPYVSQTAFIRGFQHRFEEKGLEKYYEKIGWDFSANEDLNSIRAAYQKLNITGHIWQSDGITNCLTRGDTRLKEAISKRDTPGWHINKVYTWSLDKVNSIKYALNLGVDGVMSNYAETLVTILSEDPFKQKFRLATYEDNPWETFKP
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin SpeSicTox-betaIF1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPB_ALKEH
Sequence: MSSGKIVQVIGAVVDVEFPQDQVPKIYDALIVDERGLTLEVQQQLGDGVVRTIAMGSSDGLKRSEKVSATGKPISVPVGKGTLGRIMDVLGEPVDEKGAVETEERWGIHRSAPSFAEQAGGAELLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMMELIRNIATEHAGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEYFRDEGRDILMFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLARGIAELGIYPAVDPLDSTSRQLDPLVVGEEHYNVARGVQGVLQRYKELRDIIAILGMDELSEDDKLTVARARKIQRFLSQPFFVAEVFTGAPGKYVPLKDTIASFKAILDGEYDHLPEQAFYMVGTVDEAAEKAKNL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CAPSD_MEVA
Sequence: MCFFIGLVPPGYKYLGPGNSLDQGEPTNPSDAAAKEHDEAYAAYLRSGKNPYLYFSPADQRFIDQTKDATDWGGKIGHYFFRAKKAIAPVLTDTPDHPSTSRPTKPTKRSKPPPHIFINLAKKKKAGAGQVKRDNLAPMSDGAVQPDGGQPAVRNERATGSGNGSGGGGGGGSGGVGISTGTFNNQTEFKFLENGWVEITANSSRLVHLNMPESENYKRVVVNNMDKTAVKGNMALDDTHVQIVTPWSLVDANAWGVWFNPGDWQLIVNTMSELHLVSFEQEIFNVVLKTVSESATQPPTKVYNNDLTASLMVALDSNNTMPFTPAAMRSETLGFYPWKPTIPTPWRYYFQWDRTLIPSHTGTSGTPTNIYHGTDPDDVQFYTIENSVPVHLLRTGDEFATGTFFFDCKPCRLTHTWQTNRALGLPPFLNSLPQSEGATNFGDIGVQQDKRRGVTQMGNTDYITEATIMRPAEVGYSAPYYSFEASTQGPFKTPIAAGRGGAQTDENQAADGDPRYAFGRQHGQKTTTTGETPERFTYIAHQDTGRYPAGDWIQNINFNLPVTNDNVLLPTDPIGGKTGINYTNIFNTYGPLTALNNVPPVYPNGQIWDKEFDTDLKPRLHVNAPFVCQNNCPGQLFVKVAPNLTNEYDPDASANMSRIVTYSDFWWKGKLVFKAKLRASHTWNPIQQMSINVDNQFNYLPNNIGAMKIVYEKSQLAPRKLY
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1.  The capsid encapsulates the genomic ssDNA.  Capsid proteins are responsible for the attachment to host cell receptors.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis.  Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s).  VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity).
What are the official names of this protein?
Capsid protein VP1, Coat protein VP1.
What is the protein family that this protein belongs to?
Belongs to the parvoviridae capsid protein family.
What are the subcellular locations of this protein?
[Capsid protein VP1]: Virion. SUBCELLULAR LOCATION: [Capsid protein VP2]: Virion.
Protein: HEM3_YERPN
Sequence: MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKGLFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVTICEREDPRDAFVSSHYAHLDDLPAGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLENRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEGGCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAREILAAVYLDNPAR
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ATM1_SCHPO
Sequence: MLERCPWKLISSPRNIPARSFLNSRGTYLVLRKSNILPLQHILRFSNFASKQCFPLRNGNNSASKALWNNKSKEKEPLNTSVKLASDVPDDKNVTGQMIVKDMLQYIWPKGKTNLKVRVVSALALLVAAKILNVQVPFYFKSIIDTMNTTLVQEVGALWSTVGAVVLGYGFARIFSTVFQELRNSVFAIVSQSAIRSVSSNVYQHLLNLDMNFHLSKQTGSITRAMDRGTKGISFILSSMVLHIIPITLEIAMVSGILTYKYGPSFSAIAATTVALYALFTVRTTSWRTVFRRQANAADSKASAAAIESLINYEAVKTFNNESYEMSRYEKHLSAYEKANVKVASSLAFLNSGQAIIFSTALTLMMYMGCRGIVTSNLTVGDLVMINQLVFQLSIPLNFLGSVYREMRQAFTDMEQLFSLKRINIQVKEAPDARDLVLKGGSIQFDNVHFSYNPNRPILNGCSFNIPAGAKVAFVGASGCGKSTILRLLFRFYDTDSGKILIDNQRLDQITLNSLRKAIGVVPQDTPLFNDTILYNIGYGNPKASNDEIVEAAKKAKIHDIIESFPEGYQTKVGERGLMISGGEKQRLAVSRLLLKNPEILFFDEATSALDTNTERALLRNINDLIKGSHKTSVFIAHRLRTIKDCDIIFVLEKGRVVEQGSHEQLMAKNSVYTSMWHSQESPFGESNKSGDA
What is the function of this protein?
Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by nfs1 and other mitochondrial proteins (PubMed:16306692).  Hydrolyzes ATP (By similarity).  Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity).
What are the official names of this protein?
Iron-sulfur clusters transporter atm1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CENPU_KLULA
Sequence: MDALKQRHLKLLYRQRGSASRTIDYDVVIEPELREDGDLVTDSQLTEQDDQSFPDIQVPSPDRVDDFDLNQGDGLMDKATANEDDIDHVIGDEVAAVNAPVETSDLVIDTTQFDSMTLSQLSTPLTSMATIDVLRRLLETVILVTIEERTSQFNRAGSARLRLKLKLEIKILTWFLHQSKEDLITISELNLSNNDLLYRLKQISLLKNSLSRSLLDVRSAISSYEGPNNALSEEQVALQNFKRINELILSQRIDTIINNNLPPDTSTFDTESKKGLLPTLKTLNESLQNTIG
What is the function of this protein?
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis (By similarity).  Component of the inner kinetochore COMA subcomplex, which connects centromere-associated proteins and the outer kinetochore (PubMed:29046335).  COMA interacts with other inner kinetochore proteins to form the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (By similarity).
What are the official names of this protein?
Inner kinetochore subunit AME1, CENP-U homolog, Constitutive centromere-associated network protein AME1.
What is the protein family that this protein belongs to?
Belongs to the CENP-U/AME1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: CHEB2_LEPIN
Sequence: MNYEAIVIGVSAGGINAMKTILPTLPTQFGIPIVIVQHIGARSDGEWFRILEKLCNIKIKEAEEKEEIKSGMVYVAPPNYHLLIEKDKTFSFSIGERVNFSRPSIDVLFETASEVYEDKLIGVILTGANSDGAQGLKKIKENGGLAVVQDPLTAEIALMPRSAIEATSVDYVLSLEKIAELFIRLDQNNLEQR
What is the function of this protein?
May be involved in chemotaxis.
What are the official names of this protein?
Putative protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RP07_FOWPN
Sequence: MVFPLVCSTCGRDLSEARYRLLVEQMELKKVVITYSRKCCRLKLSTQIEPYRNLTVQPSLDIN
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase 7 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 7 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: NS8A_SARS
Sequence: MKLLIVLTCISLCSCICTVVQRCASNKPHVLEDPCKVQH
What are the official names of this protein?
ORF8a protein, Accessory protein 8a, Protein non-structural 8a, ns8a.
Protein: PSTS_PSEAE
Sequence: MKLKRLMAALTFVAAGVGAASAVAAIDPALPEYQKASGVSGNLSSVGSDTLANLMTMWAEEYKRLYPNVNIQIQAAGSSTAPPALTEGTANLGPMSRKMKDVELQAFEQKYGYKPTAVPVAVDALAIFVHKDNPIKGLTMQQVDAIFSATRLCGSKQDVKTWGDLGLTGDWAKKPVQLFGRNSVSGTYGYFKEEALCKGDFRPNVNEQPGSASVVQSVSQSLNGIGYSGIGYKTASVKTVALAKKEGAAFVEDNEQNALNGTYPLSRFLYVYVNKAPNKPLDPLEAQFLKLVLSKTGQQVVVKDGYIPLPAKVAEKAIKELGL
What is the function of this protein?
Binds 1 inorganic phosphate per subunit with a KD of 0. 34 uM (PubMed:6436026).  Required for phosphate transport (Ref. 5).  In strain PAO1 implicated in host cell adhesion; in some virulent strains (e. g.  MDR25 which expresses very high levels of this protein) antibody fragments against this protein decrease host cell adhesion and increase transepithelial resistance of human epithelial cell monolayers.  Its ability to bind phosphate may allow it to acquire phosphate from its host (PubMed:18282104).
What are the official names of this protein?
Phosphate-binding protein PstS.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Periplasm. Secreted. Note=In some strains (e.g. non-MDR PAO1 and virulent clinical strain MDR25) forms long appendages distinct from flagella or pili on the cell surface: cell surface expression depends on type II secretion effector hxcR (PubMed:18282104).
Protein: 3MGH_NATTJ
Sequence: MKLDYEFFQRDAVSVAKDLIGKLLVRNLNGEELICRIVDTEAYCGPEDKGCHAYQNKRTNRTEVMYKSGGYVYVYLIYGLHYCFNVVVSKQDRPEAVFIRAGEPISGLKTMRDNRNIKSNKKTELTNGPGKLSQAMAIDKSLNGQDLVASKEIYLRHACDSQSYQIIPAKRVNIDYAEEYTDKLWRFYIRDNPFVSIN
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: Y921_STRPS
Sequence: MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEVSRFLEEHASFSFNLGDFDSIWQEYLEH
What are the official names of this protein?
UPF0346 protein SPCG_0921.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: PAAT_RAT
Sequence: METAIEDAGLDRGPTLTSSWDAACGALTQSLFLTRTGPRAQDLDFEQLLAPPAQGPDLVSLKSSLSPRDENPCFIYLKCGPNGGEEILSVGILSSARNMEVYLGEEYCGTSRGKNVCTVLDNSEHEKILLYKKYLKLESPTHACKIKLLSFGEEQCVLISKVVVHLRPRSAKPSPSSPALGSRIDLDNIQTIMESMGSKLSPGAQQLMDMIRFQQQNCLPIRDQLQSVLGTAGHKHLMALQSSPSSGVVDKASSTPFPFRTGLTPSAITENLKALIDKSTQPSGEGNTTNHNECHLMPQNHSLESDLKNAVSSFLPKKASGSSSVPNSELLPFLQNLCSQVNHLRVGHNARWQENVSKPREGTVGVPLEEQPVCSYLEKILSKNMEVMEKKLMKHIDERIYQLQEHIDAKMALLVDLLRSPNSPSPGMPLRHYDSRERLSNGER
What is the function of this protein?
ATPase that regulates mitochondrial ABC transporters ABCB7, ABCB8/MITOSUR and ABCB10.  Regulates mitochondrial ferric concentration and heme biosynthesis and plays a role in the maintenance of mitochondrial homeostasis and cell survival.
What are the official names of this protein?
ATPase PAAT, Protein associated with ABC transporters, PAAT.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: RRF_PARUW
Sequence: MSIVDQTKTKMITAIEHLKNDLKNIRTGRANPGMVEHVMIEVYGSPMRLKDVASISAPEARQLLITPFDPQNAGSIGKGIEKANLGLMPIVDAHSVRIKIPPMTEEIRKKMAKICHEEKEKTKVSIRNIRRDANELARKQKSEGIIAEDVLKKLEKNIQELTDKFCKEADEIAEKKEKEISTI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRK29_ARATH
Sequence: MEHVRVIFFFACFLTLAPFHAFAQVDSYEFDPDFNCVDRGNFTANSTFAGNLNRLVSSLSSLKSQAYGFYNLSSGDSSGERAYAIGLCRREVKRDDCVSCIQTAARNLTKQCPLTKQAVVWYTHCMFRYSNRTIYGRKETNPTKAFIAGEEISANRDDFERLQRGLLDRLKGIAAAGGPNRKYAQGNGSASAGYRRFYGTVQCTPDLSEQDCNDCLVFGFENIPSCCDAEIGLRWFSPSCNFRFETWRFYEFDADLEPDPPAIQPADSPQSAARTERTGKGKGGSKVIIAIVIPILLVALLAICLCLVLKWRKNKSGYKNKVLGKSPLSGSIAEDEFSNTESLLVHFETLKTATDNFSSENELGRGGFGSVYKGVFPQGQEIAVKRLSGNSGQGDNEFKNEILLLAKLQHRNLVRLIGFCIQGEERLLVYEFIKNASLDQFIFDTEKRQLLDWVVRYKMIGGIARGLLYLHEDSRFRIIHRDLKASNILLDQEMNPKIADFGLAKLFDSGQTMTHRFTSRIAGTYGYMAPEYAMHGQFSVKTDVFSFGVLVIEIITGKRNNNGGSNGDEDAEDLLSWVWRSWREDTILSVIDPSLTAGSRNEILRCIHIGLLCVQESAATRPTMATVSLMLNSYSFTLPTPLRPAFVLESVVIPSNVSSSTEGLQMSSNDVTVSEFSPR
What are the official names of this protein?
Cysteine-rich receptor-like protein kinase 29, Cysteine-rich RLK29.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AP5M1_MOUSE
Sequence: MALRAVWLIRHEPGTPLGGTVRFSRRYPTVEKRAKAFNGMTYVPVPEDGPFLRALLFQLRLLDDDKDFMERRDGCSRINKTSIYGLSVGGEELWPVIAFLRDSMIYASVPLVEQALSPRPPLISISGVSQGLELLLGIQDFLYSSQKNDTDLHTKLSQLPDLLLQACPLGTLLDANLQNSLNSINSVSVTQPQKQPAWKVGAYKGKAQISISITETVKCMQYGKQDIADTWQVAGTVACKCDLEGVMPAVTISLSLPTNGSPLQDIIVHPCVTSLDSAILTSSSIDTMDDSAFSGPYKFPFTPPLESFNLCHYTSQVPVPPILGSYHMKEEGVQLKVTVNFKLHESVRNNFEVCEAHIPFYNRGPITHLEYKASFGQLEVFREKSLLVWIIGQKFPKSMEISLSGTLTFGVKGHNKQPFDHICIGNTAYIKLNFRIADYTLTGCYADQHSVQVFASGKPKISAYRKLISSDYYIWNSKAPAPVTYASLLP
What is the function of this protein?
As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport.
What are the official names of this protein?
AP-5 complex subunit mu-1, Adaptor-related protein complex 5 subunit mu-1, Mu5, Mu-2-related death-inducing protein, MuD.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=May cycle on and off membranes.
Protein: RL9_PSEMY
Sequence: MEVILLEKIANLGNLGDKVNVKAGYGRNFLLPQGKATAATAENVAAFEARRAELEKLAAEKKASAEARAAQLAELEVTITATAGDEGKLFGSIGTHDIADALTASGVEVAKAEVRLPNGTIRQVGEYDVALHLHTDVEATVKVIVVAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NLA_ARATH
Sequence: MKFCKKYEEYMQGQKEKKNLPGVGFKKLKKILKRCRRNHVPSRISFTDAINHNCSRECPVCDGTFFPELLKEMEDVVGWFNEHAQKLLELHLASGFTKCLTWLRGNSRKKDHHGLIQEGKDLVNYALINAVAIRKILKKYDKIHESRQGQAFKTQVQKMRIEILQSPWLCELMAFHINLKESKKESGATITSPPPPVHALFDGCALTFDDGKPLLSCELSDSVKVDIDLTCSICLDTVFDPISLTCGHIYCYMCACSAASVNVVDGLKTAEATEKCPLCREDGVYKGAVHLDELNILLKRSCRDYWEERRKTERAERLQQAKEYWDYQCRSFTGI
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates E2-dependent protein ubiquitination (PubMed:17355433).  Plays a role in salicylic acid-mediated negative feedback regulation of salicylic acid (SA) accumulation (PubMed:18753285).  May be involved in the overall regulation of SA, benzoic acid and phenylpropanoid biosynthesis (PubMed:18753285).  Involved in defense response (PubMed:35839945).  May act as negative regulator of resistance to the necrotrophic fungal pathogen Plectosphaerella cucumerina by modulating the accumulation of the phytoalexin camalexin and the salicylic acid- and jasmonate- dependent defense pathways (PubMed:35839945).  Controls the adaptability to nitrogen limitation by channeling the phenylpropanoid metabolic flux to the induced anthocyanin synthesis (PubMed:17355433, PubMed:18552353).  Involved in the regulation of inorganic phosphate (Pi) homeostasis in a nitrate-dependent fashion (PubMed:21455488).  Directs the ubiquitination and subsequent degradation of the plasma membrane-localized inorganic phosphate transporters PHT1-1 and PHT1-4, to maintain phosphate homeostasis (PubMed:24122828).  The ubiquitination of PHTs triggers their clathrin-dependent endocytosis and trafficking to the vacuole through the endosomal pathway for degradation (PubMed:24122828).  Functions cooperatively with UBC24/PHO2 to regulate the abundance of PHT1-1, PHT1-2 and PHT1-3 in different subcellular compartments (PubMed:24122828).  Regulates Pi homeostasis by mediating, cooperatively with UBC24/PHO2, polyubiquitination of PHT1-4 and its targeting for degradation (PubMed:24474629).  Directs the polyubiquitination and subsequent degradation of the plasma membrane-localized nitrate transporter NPF2. 13/NRT1. 7, to help plants to adapt to nitrogen deficiency by regulating the source-to-sink remobilization of nitrate (PubMed:28032637).  Regulates leaf senescence during nitrogen deficiency by mediating, cooperatively with UBC24/PHO2, polyubiquitination of NAC92/ORE1 and its targeting for degradation (PubMed:30374089).
What are the official names of this protein?
E3 ubiquitin-protein ligase NLA, Protein BENZOIC ACID HYPERSENSITIVE 1, Protein NITROGEN LIMITATION ADAPTATION, RING-type E3 ubiquitin transferase BAH1.
Protein: ZGPAT_DROMO
Sequence: MDEYEAQLLVVKQALLVTSDEQQRDELIALQTNLEELLALTRGSEPEATSDTKTPETSDNIDDELQRFQSELIDLEHQQADPGEDQQRLEELRTKYNGLLGEKCSAPHEHSWGALSYHNALICGVDDELIVDKNGILDVRLRVLFTNPTHREMLPCNYFLEGECRFDEVRCRYSHGALVPGSSIKDYKAPDFHRLARNCSVLAKLQDRLWHRGRVLCVNFVEQQCRVRLDGQEHKERERDFPFEELFPLVTAEDDDLTSESEESNETDGSDAGNDSDMDDFEAARQARMVELSLFTFKPTERLGAWEQYTRGIGSKLMANMGYIHGTGLGSDGRGIVTPVSAQILPQGRSLDACMELREAANGDKDYFSVERKLKRAQRRQEAANEKAYERASKRTDVFAFLNTSVLGQGSQQTENANKKTKPNNLQQHSNKTLNVETVRIADDIRRKQRDIAKVQQSLARNATDAQLQKRLNVQLQAQKQELATLQAQETSLCKEQQTRKSKNKMFEF
What is the function of this protein?
Transcription repressor.
What are the official names of this protein?
Zinc finger CCCH-type with G patch domain-containing protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL8A_YEAST
Sequence: MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGKSKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIVKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDKRAKNSDSA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L8-A, L4, L4-2, L7a-1, Large ribosomal subunit protein eL8-A, Maintenance of killer protein 7, RP6, YL5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_NEIG1
Sequence: MKALLLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQAEAMVEAGVGLDAVVEIDVSDSVIVDRMSGRRVHLASGRTYHVTYNPPKTEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTEVLVDFYSKLEGEHAPKYIKVDGTQAVEAVKAEVLGALGK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWET1_MOUSE
Sequence: MEAGGVADSFLSSACVLFTLGMFSTGLSDLRHMQRTRSVDNIQFLPFLTTDVNNLSWLSYGVLKGDGTLIIVNSVGAVLQTLYILAYLHYSPQKHGVLLQTATLLAVLLLGYGYFWLLVPDLEARLQQLGLFCSVFTISMYLSPLADLAKIVQTKSTQRLSFSLTIATLFCSASWSIYGFRLRDPYITVPNLPGILTSLIRLGLFCKYPPEQDRKYRLLQT
What is the function of this protein?
Mediates sugar transport across membranes (By similarity).  May regulate the expression of RAG1 a gene involved in V(D)J recombination.
What are the official names of this protein?
Sugar transporter SWEET1, MmSWEET1, RAG1-activating protein 1, Solute carrier family 50 member 1.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=May also localize to the endoplasmic reticulum.
Protein: PSBZ_EUGGR
Sequence: MLLFTFTFQALVLALIIFSFILVLTLPVIFASPKGWENNKSRIWLACRFWFFLVFLIGILDGIFL
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: DCUP_LEGPA
Sequence: MFDLNQSLFLRALRRQPVERTPIWIMRQAGRYLPEYRKVREHAGDFLNLCKNPELACEVTLQPLRRYALDAAILFSDILTIPDAMGLGLYFAEGEGPCFTNPLQDTKAIHALKIPSIPESLSYVFDAARLIRQEMPKELPLIGFSGSPWTLACYMVEGGSSRDFKRILNLIYTEKEAAHLLLNKLAVSVTAYLTEQIKAGVNAVMIFDTWGGVLTPQNYKDFSLAYMHQIVQQLKNEYPDIPVILFTKNGGQWLEWMAETGCDALGVDWTCDLASARKRVGGKVALQGNLDPAVLLTAKNCIRREVGSVLASYGYGTGHIFNLGHGITPDVPPENVAIMIEAVHEISPQYHL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.