PharMolix/UniProtQA huggingface dataset:
Protein: PVK1_AUSRA
Sequence: EAAGLLPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
CAPA-Periviscerokinin-1, CAPA-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TGT_LEPIC
Sequence: MIFQTTSEDTLTKARTGILNLNGIELKTPVFMPVGTRGVVKTLSADDLEELEYSLILGNTYHLYLRPGTSVLDRFGGLKKFSTWKKALLTDSGGYQVFSLNSLFKYEQDGVRFQSHIDGSRHYFTPNSVIDIQRSIGSDIMMVLDDCAPFDSGPERLKQSLDRTHRWAEMSVQYWEKNKNSQHLFGIFQGGIDLDFRLESLNTITSLPFDGIAIGGLSVGEPRKDFIRILDGISAHTDRNRPLYLMGVGTVPDILDGVKNGVDMFDCVLPTRNARNGQVFTTLGKINLRNEKWKSSDTPMDPNCTCKVCKRYSIGYIRHLHHVGEITAFSLSTYHNLHFMKNFLTEIQNSIQKGEFLEIYAKWKNLYEKPEFSG
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RK12_CYAPA
Sequence: MSSKTDEILEQLKGLTLIEAADLVKAIEEAFGVDASAPVGGGMVMMAPAAGGGADAAEEKSAFDLVLEEVPADKKIAVLKVVRSLTNLGLKEAKDLVEATPKVVKEGASKDELKQLKKNLKQLEQK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L12, cyanelle.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: RL5_METS3
Sequence: MNPMNEVQISKATVSIGVGEAGEKLSRAITLLEQMFDQTPVKTFSKVTNPEFGIRKRQPIACKLTLRGEKADKAIEMVLEGINKNIKPTQFDAQGNLSFGIKEHIDIPGMKYNPDIGIFGMNVSVTFEKPGYRIAKRRIQQKKVPAKHRISKEETMKYMEDNFNVNYVTE
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MINE_SALCH
Sequence: MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: ATPB_IPOWR
Sequence: MRINPTTSGSEVSAVEKKNLGRIVKIIGPVLDVAFPPGKMPNIYNALVVQGRDNEQTNVTCEVQQLLGNNRVRAVAMSDTDGLMRGMGVIDTGAPISVPVGGSTLGRIFNVLGQPVDNLGPVDTNTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYLEMKESGVINEENIPESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLKT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PSBH_STAPU
Sequence: MATQIIKDANSKGRRTALGDILKPLNSEYGKVAPGWGTTVLMGVFMALFAVFLVIILELYNASVVLDGIPVSWQ
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL32_THEAC
Sequence: MNRLLDENQRRLLKIKNVMARKRVEFHRQEWFRYKKLGDAWRKPRGKHSKLREHLARRPPVVDAGFRSPSAVRGMHPSGYYEVLIHNVNELESVDPRFQAVRIASSVGSRKRQEIIKRSEELNLKVLNGR
What are the official names of this protein?
50S ribosomal protein L32e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: IFA1_CAEEL
Sequence: MMEITRETMSFTSTTPSARAPLGGRTTGNVTSQDRMLKIVTEMRSGAGSGLSPFGQNAASTIRDSREREKKEMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNIRNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDALLVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQVQTLLEEIDFLRRVHDNEIKELQTLASRDTTPENREFFKNELSSAIRDIREEYDQVNNVHRNDMESWYRLKVQEIQTQSARQNMEQGYAKEEVKRLRTQLSDLRGKLADLESRNSLLEKQIQELNYQLEDDQRSYEAALNDRDSQIRKMREECQALMVELQMLLDTKQTLDAEIAIYRKMLEGEENRAGLKQLVEQVVKTHAITQETDTETMRVVKGETASRQSFQRSAKGNVSIHEASPDGKFIVLQNTHRAKDEAIGEWKLKRRIDGKRENVYTLPRDFVLRAGKTLKIFARNQGVASPPDQLVYDAEDSFGSGNNVQTILFNKEGEERATHIQRQSTA
What is the function of this protein?
Cytoplasmic intermediate filaments make up the structural component of the cytoskeleton providing mechanical strength to cells.  Essential protein required during embryogenesis especially for survival past the L1 larva stage, involved in intestine morphogenesis.
What are the official names of this protein?
Intermediate filament protein ifa-1, Cel IF A1, Intermediate filament protein A1, IF-A1.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT12_HELAN
Sequence: MPTLNQLIRHGREEKRRTDRTRALDQCPQKQGVCLRVSTRTPKKPNSALRKIAKVRLSNRHDIFAYIPGEGHNLQEHSIVLIRGGRVKDLPGVKFHCIRGVKDLLGIPDRRKGRSKYGAEKPKSR
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS5_LEPCP
Sequence: MAKFQPKVADEGRDDGMREKMIQVNRVTKVVKGGRIMAFATLTVVGDGDGRVGMGKGKAREVPVSVQKAMESARRGLVKIPLRNGTVPHNATGEHGAAKVLLAPAPAGTGIIAGGPMRAVFEVLGITDIVAKSLGSSNPYNMVRATFDALSRMTTASQVAAKRGLTIEQIFN
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: TX36A_PHONI
Sequence: MKVAILFLSILVLAVASESIEESRDDFAVEELGRATCAGQDQPCKETCDCCGERGECVCGGPCICRQGYFWIAWYKLANCKK
What is the function of this protein?
Toxin that is known to potentiate erectile function (PubMed:18397797).  It binds voltage-dependently to sodium channels (Nav), inhibits the inactivation of the activated channels and decreases the peak inward current (PubMed:19231838, PubMed:26119670).  The toxin delays inactivation of Nav1. 2/SCN2A, Nav1. 3/SCN3A, Nav1. 4/SCN4A and Nav1. 8/SCN10A, slows the inactivation process and decreases the sodium peak amplitude of Nav1. 5/SCN5A and Nav1. 6/SCN8A (PubMed:26119670).  In vivo, it enhances erectile function by inducing the release of nictric oxide (NO): it slows the sodium current, leading to depolarization, which leads to an increase in calcium influx (probably via activation of N-type calcium channels) which in turn activates neuronal NO synthase (nNOS/NOS1), inducing nitric oxide (NO) production (PubMed:20722794, PubMed:21975567).  In a final step, NO activates soluble guanylate cyclase (GUCY1A1/GUCY1B1) which in turn increases cGMP formation, resulting in penile erection (PubMed:23583324).  It is noteworthy that the toxin does not provoke erection by inhibiting phosphodiesterase type 5 (PDE5A), an enzyme that hydrolysis cGMP (PubMed:23583324).  In vivo, it also causes scratching, lacrimation, hypersalivation, sweating and agitation followed by spastic paralysis of the anterior and posterior extremities and death at dose levels of 0. 79 mg/mouse (PubMed:1397265, PubMed:16278100).  It is insecticidal to the larval and adult forms of the house fly (PubMed:1397265).  The toxin also improves cavernosal relaxation in different models where erectile dysfonction is observed, such as deoxycorticosterone-acetate (DOCA)-salt hypertensive rats, mice models for type-1 diabetes, as well as elderly rats (PubMed:18397797, PubMed:21975567, PubMed:22925420).
What are the official names of this protein?
Delta-ctenitoxin-Pn2a, Delta-CNTX-Pn2a, Delta-CNTX-Pn1c, Neurotoxin Tx2-6, PnTx2-6.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PVK2_SCHGR
Sequence: GLLAFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, Lom-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUD_FRATN
Sequence: MQAFKKLTSSAIPLWLSDIDTDMIIPANFLTQTTKDGYGKSLFHNLKEKDSSFVFNNPDYSNSEILIAGDNFGCGSSREHAVWALTQAGIKVIIAPSFSDIFFNNAAKNGLLLISLDKDTVKELCDKAEDPKFSMTIDLQEQTVSADGSIYSFDYDPFRKDCLIRGLDDMTYLIEHLDIIKQFEQSQRG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PEF1_DANRE
Sequence: MSYQYGQGYSGPGGNAPQWQQPPRAPYAGGPAAGQYGSPYGSAPPGQQYGGGSPYGSYGQPGPRAPYGGGQAPGGPYGGYGQPQGGPYRQQGSAGNVPPGVNPEAYQWFSTVDSDQSGYINAKELKQALMNFNNSSFNDETCIMMLNMFDKTKSGRVDVFGFSALWTFLQQWRAAFQQFDRDRSGSINTNEMHQALSQMGYNLSPQFIQELVNRYSVRGGTGVLQLDRFIQVCTQLQSMTQAFREKDTGMTGNVRMSYEDFLSSAITRLM
What is the function of this protein?
Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium.  Acts as a negative regulator of ER-Golgi transport (By similarity).
What are the official names of this protein?
Peflin, PEF protein with a long N-terminal hydrophobic domain, Penta-EF hand domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein.
Protein: LLDP_SALTI
Sequence: MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVVIALAVALLFYKMPVDHALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFNPLYAAGLCLIVNTAPVAFGAMGIPILVAGQVTDLDSFEIGQMVGRQLPFLTIIVLFWIMAIMDGWRGVKETWPAVMVAGGSFAIAQYLSSNFIGPELPDIISSLVSLVCLTLFLKRWQPVRIFRFGDMGASQVDQTLARTRYTTGQIVRAWSPFLFLTATVTLWSIPPFKALFAPGGALYDWVINVPVPYLDKLVARMPPVVHEATAYAAVYKFDWFSATGTAILFAALLSIVWLKMKPSAAIQTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGSAFTFFSPFLGWLGVFLTGSDTSSNALFASLQATAAQQIGVSDVLMVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP
What is the function of this protein?
Uptake of L-lactate across the membrane (By similarity).  Can also transport D-lactate and glycolate (By similarity).  Seems to be driven by a proton motive force (By similarity).
What are the official names of this protein?
L-lactate permease.
What is the protein family that this protein belongs to?
Belongs to the lactate permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GNL1_PONAB
Sequence: MPRKKPFSVKQKKKQLQDKRERKRGLQDGLRSSSNSRSGSRERREEQTDTSDGESVTHHIRRLNQQPSQGLGPRGYDPNRYRLHFERDSREEVERRKRAAREQVLQPVSAEVLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQEYLGKIHGAYSSEKLSYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTGELGLALVLVLNKVDLAPPALVVAWKHYFHQHYPQLHVVLFTSFPRDPRTPQDPSSVLKKSRRRGRGWTRALGPEQLLRACEAITVGKVDLSSWREKIARDVAGATWGNGSGEEEEEEDGPAVLVEQQTDSAMEPTGPTRERYKDGVVTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPSLLPRQLQVLAGIYPIAQIQEPYTAVGYLASRIPVQALLHLRHPEAEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFHPPGYSEQKGTWESHPETTELVVLQGRVGPAGDEEEEEEEELSSSCEEEGEEDRDADEEGEGDEDTPTSAPGSSLAGRNPYALLGEDEC
What is the function of this protein?
Possible regulatory or functional link with the histocompatibility cluster.
What are the official names of this protein?
Guanine nucleotide-binding protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family.
Protein: SELA_HELHP
Sequence: MQHLLKSLPKVDTLLAHNELKMFQKSTLLPLIQSHLSLLRENICSNTLSPKELESALNEIIPVIKKKAIEATKPTLTRVINATGVVIHTNLGRSVLSPQILDEITPFLRSYHTLEYDLAKGKRSERYTHTKQILCEMFGCEDALLVNNNAAAVLLILNTFAAHKEVIISRGELVEIGGSFRIPEVMKSASSILCEVGATNKTHLKDYENAINEQSAMIMKVHQSNFKQIGFVKQCHIKEIIHLAQKHHLIDYFDLGSGHIGALPLADEPSVREICKYKPSLLSFSGDKLLGGPQVGIIIGKSQLIAQLKHNQLLRALRVDKFSILALQATLKAYQNKEYHKIPTLAMLAFTPKELESKAKNLKKRILASSIASELEVEVIPLHSLAGGGSVPHLSFDSFGISLQAKHLQVQDFEFALRALGLISCIQGEKILLDVRTLLEGDEERIMEILGEVLSS
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_PARD8
Sequence: MKSIVLLRHGESIWNKENRFTGWTDVDLTEKGVAEAYRAGNLLKEKGYVFNKAYTSYLKRAVKTLNCVLDRMDQDWIPVEKSWRLNEKHYGSLQGLNKSETAQKYGDEQVLIWRRSYDIAPLPLSEDDPRNPRFDIRYKDVPDKELPRTESLKDTVERILPYWKEVIFPTLRTADQILVAAHGNSLRGIIKYLKNISDEEIVHLNLPTAVPYVFEFDDDLKLVNDYFLGDPEEIKKLMEAVANQGKKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: EFP_ACIAC
Sequence: MKIAQEIRAGNVIMHGKDPMIVLKTEYARGGRGAATVRMKLKALLNNMGTEVVFKADDKIDNVILDKKECTYSYFADPMYVCMDAEYNQYEVEAENMGDALNYLEDGMAVEVVFYDGKAISVELPTSVEREITWTEPAVKGDTSGKVLKPAKIATGFEVAVPLFVNQGDRIEIDTRTGEYRKRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_MYCPA
Sequence: MTGQRATPQPTLDDLPLRDDLRGKSPYGAPQLAVPVRLNTNENPHPPSRALVDDVVRSVARAAADLHRYPDRDAVQLRSDLARYLTAQTGVQLGVENLWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTRTEWLQAARADDFSLDVDAAVAAVTERTPDVVFVASPNNPSGQSVSLSGLRRLLDAAPGIVIVDEAYGEFSSQPSAVQLVGEYPTKLVVTRTMSKAFAFAGGRLGYLIATPAVIEAMLLVRLPYHLSSVTQAAARAALRHADDTLGSVAALIAERERVSTALTGMGFRVIPSDANFVLFGEFTDAPASWQRYLDAGVLIRDVGIPGYLRATTGLAEENDAFLRASAQLAATELAPVNVGAIANAAEPRAAGRDRVLGAP
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: GCH1L_STRPQ
Sequence: MKAKTLIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLDIRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNIDIVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTVRLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAVDPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: LIPA_SHEPC
Sequence: MNRPERLQPGVKLRDADKVSRIPVKIVPSERDTMLRKPDWLRVKLPASNQRILDIKQALRSNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPLKPDAEEPVKLAQTIRDMKLKYVVITSVDRDDLRDGGAQHFADCIREIRKLNPAIKIEILVPDFRGRIDAALDILATEPPDVFNHNLETAPMHYRKARPGANYQWSLDLLKRFKERHPNVPTKSGLMMGLGETNEEIAQVLRDLREHKVEMLTLGQYLQPSKFHLPVERYVPPAEFDELKALADELGFTHAACGPLVRSSYHADLQAQGKEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIF_ECOLI
Sequence: MNMKTIEDVFIHLLSDTYSAEKQLTRALAKLARATSNEKLSQAFHAHLEETHGQIERIDQVVESESNLKIKRMKCVAMEGLIEEANEVIESTEKNEVRDAALIAAAQKVEHYEIASYGTLATLAEQLGYRKAAKLLKETLEEEKATDIKLTDLAINNVNKKAENKA
What are the official names of this protein?
Protein YciF.
Protein: RUVC_ACTP2
Sequence: MPIILGIDPGSRVTGYGVIRQTGRHLEYLGSGAIRTSVDDLPTRLKRIYAGVTEIITQFHPDMFAIEQVFMAKNADSALKLGQARGTAIVAAVNHDLPVFEYAARLVKQTVTGIGSADKIQVQDMVTRMLQLSSKPQADAADALAIAITHAHSIQHSLIVAKQSDQKVGSDKEQILALMKTRYSRGRFRLKG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NOP9_YEAST
Sequence: MGKTKTRGRRHQDKQRKDEFEPSSNSAKEHIQQEESTYNDEAEIKETQPQMFFGVLDREELEYFKQAESTLQLDAFEAPEEKFQFVTSIIEEAKGKELKLVTSQITSKLMERVILECDETQLKDIFQSFNGVFFGLSCHKYASHVLETLFVRSAALVERELLTPSFDNNEKEGPYVTMENMFLFMLNELKPHLKTMMNHQYASHVLRLLILILSSKTLPNSTKANSTLRSKKSKIARKMIDIKDNDDFNKVYQTPESFKSELRDIITTLYKGFTNGAESRSDISQSTITKFREYSVDKVASPVIQLIIQVEGIFDRDRSFWRLVFNTADEKDPKEESFLEYLLSDPVGSHFLENVIGSARLKYVERLYRLYMKDRIVKLAKRDTTGAFVVRALLEHLKEKDVKQILDAVVPELSMLLNSNMDFGTAIINASNKQGGYLRDDVIAQLIQKYYPEKSDAKNILESCLLLSASTLGNTRDDWPTAEERRRSVFLEQLIDYDDKFLNITIDSMLALPEERLIQMCYHGVFSHVVEHVLQTTRVDIIKRKMLLNILSKESVNLACNVYGSHIMDKLWEFTAKLTLYKERIARALVLETEKVKNSIYGRQVWKNWKLELYVRKMWDWKKLIKEQEFEIFPNSKPLQPKPEKHSRERNNSKEGSAFKKQKHYR
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Component of the 90S pre-ribosome involved in production of 18S rRNA and assembly of small ribosomal subunit.  Component of the pre-40S ribosome required for release from the nucleolus.
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y501_CITK8
Sequence: MEMTNAQRLILSNQYKMMTMLDPTNAERYRRLQTIIERGYGLQMRELDREFGELKEETCRTIIDIMEMYHALHVSWTNLKDAQTIDERRVTFLGFDAATEARYLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHSCPRQYHLSSNEINQIINA
What are the official names of this protein?
UPF0304 protein CKO_00501.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: OR71A_DROME
Sequence: MDYDRIRPVRFLTGVLKWWRLWPRKESVSTPDWTNWQAYALHVPFTFLFVLLLWLEAIKSRDIQHTADVLLICLTTTALGGKVINIWKYAHVAQGILSEWSTWDLFELRSKQEVDMWRFEHRRFNRVFMFYCLCSAGVIPFIVIQPLFDIPNRLPFWMWTPFDWQQPVLFWYAFIYQATTIPIACACNVTMDAVNWYLMLHLSLCLRMLGQRLSKLQHDDKDLREKFLELIHLHQRLKQQALSIEIFISKSTFTQILVSSLIICFTIYSMQMSPVLQDLPGFAAMMQYLVAMIMQVMLPTIYGNAVIDSANMLTDSMYNSDWPDMNCRMRRLVLMFMVYLNRPVTLKAGGFFHIGLPLFTKTMNQAYSLLALLLNMNQ
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity).
What are the official names of this protein?
Putative odorant receptor 71a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPMA_SHIFL
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.