PharMolix/UniProtQA huggingface dataset:
Protein: NSP1_CHATD
Sequence: MSFTFGQPSTSGASGQSNTSTAPASGGLFGSTTGSSTPAFSFGNTSGTQSGSLFGGATTGQKTSLFGNTSSTTPAGTPATSLFGQSTSSSSGPSLFGNASKPSGNLFGNTSTSAAGSSTPAGTPSLFGSKTATTSAGASSTTPAATAGSGSLFGSTTATTQGSSTPTSTGLFGGSSTASKSLFGSTTTPATGTSGSQTTPAKPLFGSFGSTTPAGAPPTDATKTAGLFGNLSKPATTGTSTPTLFGSTSATTQGQSSTPLFGAKPAETSTTTAASGAATPATSAPASTTPTLFGGATLTSSAPAASTSTSTATASTPAATKPLFGATATTSAPGSSTTTATPGLFSTTPATTAAAGSSTATSTLFGTKPATTTAAAASSTPAATSTPSLFGSKPASTTAPASGTPTTTTAPASTSAPATTTAAPTSGASATASTTTAGQDAKTTTAGLGASTVGPQSQLPRLKNKTMDEIITRWATDLAKYQKEFKEQAAKVMEWDRLLVENGEKIQKLYTSTYEAERASNEIERQLSNVESQQEELTAWLDRYERELDELYAKQMGSAAGEQAAGPDQERERTYKLAEKLTDQLDEMGKDLAKMIKEINDMSNTLSKGSKPDDPLTQIVRVLNGHLAQLQWIDTNAAALQAKVAAAQKAAGSMGANVPGTETDAAESFYRSYRGGLK
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm).  NSP1 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, pre-ribosome, signal recognition particle (SRP), and protein transport.
What are the official names of this protein?
Nucleoporin NSP1, Nuclear pore protein NSP1, Nucleoskeletal-like protein.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin NSP1/NUP62 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Protein: NOCQ_AGRFC
Sequence: MDLTLLQWGDAGWGDELARGAMMTVVVAACSYFFGIIFGSLFAAAKLSRFWSLRLLGDVYTTVVRGVPELLIIFLVFFGGGTLLRTIANGLFGYEGYIEPPIFVIGVLCISVSAGAYATEVIRAAVLAVPPGQIEAAKSIGMGPWLRLRRVLIPQAARFALPGLGNVWQFTLKDTSLISVVGLVEIMRTAAMGAGSTKQPFTFYITAFVIFLLLSSVSNRGFLKAEKWANRGVRSQ
What is the function of this protein?
Component of the nopaline active transport system probably consisting of four subunits: Q, M, P and T.  This system is also capable of transporting octopine provided that catabolic functions are induced with nopaline.
What are the official names of this protein?
Nopaline transport system permease protein NocQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCGS_BACSU
Sequence: MKRRVETITFDGGTLEYSVTGKGTPILVMHGGHSNCYEEFGYTALIEQGYSIITPSRPGYGRTSKEIGKSLANACRFYVKLLDHLQIESVHVIAISAGGPSGICFASHYPERVNTLTLQSAVTKEWLTPKDTEYKLGEILFRPPVEKWIWKLISSLNNAFPRLMFRAMSPQFSTLPFQRIKSLMNEKDIEAFRKMNSRQRSGEGFLIDLSQTAAVSLKDLQAIICPVLIMQSVYDGLVDLSHAHHAKEHIRGAVLCLLHSWGHLIWLGKEAAETGSILLGFLES
What are the official names of this protein?
Uncharacterized hydrolase YcgS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: CHST4_MOUSE
Sequence: MMLLKKGRLLMFLGSQVIVVALFIHMSVHRHLSQREESRRPVHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFTSSTAWKLHMAVRDLLRSVFLCDMSVFDAYMNPGPRKQSSLFQWEQSRALCSAPVCDFFPAHEISSPKHCKLLCGQQPFDMVEKACRSHGFVVLKEVRFLSLQALYPLLTDPSLNLHVVHLVRDPRAVFRSREHTTIELVVDSHIVLGQHLETIKEEDQPYYAMKIICKSQVDIVKAIQTLPEALQQRYLFLRYEDLVRAPLAQTTRLYKFVGLDFLPHLQTWVHNVTRGKGMGQHAFHTNARNALNVSQAWRWSLPYEKVSQLQDACGEAMDLLGYLQVRSQQEQGNLSLDLLSSSHILGQVFREG
What is the function of this protein?
Sulfotransferase involved in SELL/L-selectin ligand biosynthesis pathway.  Catalyzes the transfer of the sulfate group from 3'-phospho-5'-adenylyl sulfate (PAPS) onto the hydroxyl group at C-6 position of the non-reducing N-acetylglucosamine (GlcNAc) residue within O-linked mucin-type glycans (PubMed:10435581, PubMed:16227985, PubMed:15319280, PubMed:16227986, PubMed:14597732, PubMed:15111310).  Contributes to generate sialyl 6-sulfo Lewis X determinant (also known as MECA-79 epitope) for SELL recognition, a prerequisite for continuous lymphocyte homing into peripheral lymph nodes and antigen immune surveillance.  Transfers the sulfate group primarily on core 2 GlcNAcbeta1-6(Galbeta1-3)GalNAcalphaSer/Thr and extended core 1 GlcNAcbeta1-3Galbeta1-3GalNAcalphaSer/Thr based O-linked glycans on CD34 and GLYCAM1 peripheral node addressins (PNAds) expressed on the lumenal side of high endothelial venules (HEVs) (PubMed:10435581, PubMed:16227985, PubMed:15319280, PubMed:16227986, PubMed:15111310, PubMed:14593101).  The recognition of PNAds by SELL initiates a multistep process comprising tethering and rolling of blood lymphocytes on HEVs against the blood flow, followed by chemokine signaling, integrin-mediated lymphocyte adhesion onto endothelial cells and lymphocyte transendothelial migration.  Modulates rolling velocity and differential T and B lymphocyte recruitment into peripheral lymph nodes, with a major role in B lymphocyte homing (PubMed:16227985, PubMed:15319280, PubMed:16227986, PubMed:14597732, PubMed:10435581).  Might be redundant in sulfation of MADCAM1 and lymphocyte trafficking to mesenteric lymph nodes (PubMed:10435581, PubMed:11520459, PubMed:16227986).  Can also sulfonate core 3 GlcNAcbeta1-3GalNAc-R based glycans as well as GlcNAcbeta1-3Galbeta1-Glc, GlcNAcbeta1-6ManOMe and GlcNAcbeta1-2Man oligosaccharides, which might be ectopically expressed during tumorigenesis (By similarity).
What are the official names of this protein?
Carbohydrate sulfotransferase 4, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3, GST-3, High endothelial cells N-acetylglucosamine 6-O-sulfotransferase, HEC-GlcNAc6ST, L-selectin ligand sulfotransferase, LSST, N-acetylglucosamine 6-O-sulfotransferase 2, GlcNAc6ST-2, Gn6st-2.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: HEM3_CAMC1
Sequence: MKEIKIATRKSILALWQSEHIKARIEAQHKGMKVVLEGMKTKGDVILDTPLAKIGGKGLFTKELEDSMLKGETDIAVHSLKDVPVVFPEGLRLAAICSREDTRDAMISEKFAKFSDLPHGAKVGTTSLRRKMQLLIMRPDLEIISLRGNVQTRLRKLKEGEFDAIILAMAGINRLNIKAEVAHIYTFGFDEMIPAMGQGALGIEARDEKQILDETSFLNDENAVIETTIERDFVSVLEGGCQVPIGISARLKGDEISIDAIVGLPDGSEYIKDSLKTSKDKFQSVGKELAHKFIEKGARELLKRAEEMA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RS19_MYCLB
Sequence: MPRSLKKGPFVDDHLLKKVDVQNEKNTKQVIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTEAMVGHKLGEFAPTRTFKGHIKDDRKAKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: YA9D_SCHPO
Sequence: MFQLPMIVEANDMKIKYYKRRNCYTLLIFKYKESKKINVYKRKKSDEVVEDCNKLKCTFFMIEEWHLLAILYDKSKYIKIIICSVLLKLNTTVIIRRNTHTKVYVMNKFYQKLKK
What are the official names of this protein?
Uncharacterized protein C13G6.13.
Protein: PSBC_PINKO
Sequence: MKTLYSLRRSYPVETLFNGTIALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEIVDTFPYFVSGVLHLISSAVLGFGGIYHALIGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGVGAFLPVLKALYFGGVYDTWAPGGGDVRKITNPTLNPSAIFGYLLKSPFGGEGWIVSVDNLEDVIGGHVWLGSICIFGGIWHILTKPFAWARRAFVWSGEAYLSYSLAALSLFGFIACCFVWFNNTVYPSEFYGPTGPEASQAQAFTFLVRDQRLGASVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDLRAPWLEPLRGPNGLDLSKLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KRFJ_COTJA
Sequence: MSCYSPCQTVACGPAPLANSCNEPCVLRCADSSVAIQPPPVVVTLPGPILSSFPQSTAVGSTASAAVGSSLSAGSVPVGARGSLGLGGFGWSGLGRGLCGTLGRGNVFC
What are the official names of this protein?
Beta-keratin-related protein.
What is the protein family that this protein belongs to?
Belongs to the avian keratin family.
Protein: RPCH_PENMO
Sequence: MVRAVVATLLVVLVVASCVSAQLNFSPGWGKRAAAGGEGTGMHPPAGAVVPPPSSLAGESCGTIPVTTVMHIYRLIRAEATRLVQCQDEEYLG
What is the function of this protein?
This hormone adapts the animal to light backgrounds by stimulating concentration of the pigment of its red body-chromatophores.
What are the official names of this protein?
Red pigment-concentrating hormone, PmRPCH, RPCH.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYV_ACTP2
Sequence: MTQNLQMADRFDSSAVEQALYKHWEEQGYFKPTENPSLPSYCIAIPPPNVTGSLHMGHAFQQTLMDTLIRFNRMEGNNTLWQTGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFINKIWDWKAYSGGTISQQMRRLGNSIDWDRERFTMDEGLSNAVKEVFVRLHEEGLIYRGKRLVNWDPKLHTAISDLEVENKESKGSLWHFRYPLANGAKTADGKDYLVVATTRPETVLGDTAVAVHPEDERYQSLIGKTVVLPLANREIPIVADEYVDREFGTGVVKITPAHDFNDYEVGKRHGLPMVNVMTMNADIRAEAEIIGTDGKPLTTYEAKIPADYQGLERFAARKKVVADFEALGLLDEIKPHDLKVPYGDRGGVPIEPMLTDQWYVSVKPLAEVATKAVEDGEIQFVPKQYENLYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVARSEEEVRQKHNLPADLALRQDEDVLDTWFSSGLWTFSTLGWPEQTKELKMFHPTDVLITGFDIIFFWVARMIMFTMHFVKDENGKPQVPFKTVYVTGLIRDEQGQKMSKSKGNVLDPIDMIDGISLEDLLEKRTGNMMQPQLAEKIAKATRKEFENGIAAHGTDALRFTLAALASNGRDINWDMKRLEGYRNFCNKLWNASRFVLTNDKLDLSAGEVEYSLADRWIESKFNRTVGEFREALSQYRFDLAANAIYDFTWNEFCDWYLELTKPVFANGTEAQKRGASQTLVRVLEKLLRLAHPIMPFITEEIWQKVKGFAGIDADTIMLQPFPKVVKSELDESAEMQIGWIKELIIAVRNIRAESNIAPSKGLEFLVRNVSDEQRKILAENDRLLKAMAKLDSVQVLSADENAPLSVAKLVGNVEVLIPMAGFINKEAELARLTKEIEKMRGEITRIENKLGNEAFVAKAPEAVIAKEREKMQEYQNGLEKLQTQYQAIENL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRF_HUMAN
Sequence: MRLPLLVSAGVLLVALLPCPPCRALLSRGPVPGARQAPQHPQPLDFFQPPPQSEQPQQPQARPVLLRMGEEYFLRLGNLNKSPAAPLSPASSLLAGGSGSRPSPEQATANFFRVLLQQLLLPRRSLDSPAALAERGARNALGGHQEAPERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK
What is the function of this protein?
Hormone regulating the release of corticotropin from pituitary gland (By similarity).  Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).
What are the official names of this protein?
Corticoliberin, Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone.
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_STRPB
Sequence: MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIKEHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: LSPA_METPP
Sequence: MARTTTLGRGGLLTWLGVALIVIVLDQLTKTLILGHFQYGDARHVTGFFNIVRVHNTGAAFSFLAGASGWQRWFFVGLGLVAAGFIVWMLRSQGHQRLFAWALSLILGGAIGNVIDRLLHGYVVDFLDVHWAGWHFPAFNIADSAITVGAALLILDELRRVRRG
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KRA65_MOUSE
Sequence: MCGYYGNYYGGRGYGCCGCGGLGYGYGGLGCGYGSYYGCGYRGLGCGYGYGCGYGSRSLYGCGYGCGSGYGSGFGYYY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 6-5, Keratin-associated protein 16-8, Keratin-associated protein 16.8.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 6 family.
Protein: RL10A_DICDI
Sequence: MSKISSDQVRSIVSQLFKEAQESKRGFLETVELQINLKNYDTKKDKRFSGQIKIGTVTKPKLSVCVFADQQHCDEATKIGAEFMDIEALKKIGPKNKKAIKKLSKKYDAFLASESILRQVPKLLGPGLNKVGKFPTLLTHSEDMASKINDVKSTVKFQLKKVLCLAVAVGHIELTEREVATNIIQSINFLVSLLKKGWQNIKTLYVKTSMGPSHRVY
What are the official names of this protein?
60S ribosomal protein L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PKNF_MYCTU
Sequence: MPLAEGSTFAGFTIVRQLGSGGMGEVYLARHPRLPRQDALKVLRADVSADGEYRARFNREADAAASLWHPHIVAVHDRGEFDGQLWIDMDFVDGTDTVSLLRDRYPNGMPGPEVTEIITAVAEALDYAHERRLLHRDVKPANILIANPDSPDRRIMLADFGIAGWVDDPSGLTATNMTVGTVSYAAPEQLMGNELDGRADQYALAATAFHLLTGSPPFQHANPAVVISQHLSASPPAIGDRVPELTPLDPVFAKALAKQPKDRYQRCVDFARALGHRLGGAGDPDDTRVSQPVAVAAPAKRSLLRTAVIVPAVLAMLLVMAVAVAVREFQRADDERAAQPARTRTTTSAGTTTSVAPASTTRPAPTTPTTTGAADTATASPTAAVVAIGALCFPLGSTGTTKTGATAYCSTLQGTNTTIWSLTEDTVASPTVTATADPTEAPLPIEQESPIRVCMQQTGQTRRECREEIRRSNGWP
What is the function of this protein?
Phosphorylates the FHA domains of the ABC transporter Rv1747, the heat-shock protein GroEL 1, and Rv0020c.  May play a role in the regulation of glucose transport, cell growth and septum formation.
What are the official names of this protein?
Serine/threonine-protein kinase PknF.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GCSH_MARN8
Sequence: MSEIPSDLKYIETHQWVRVDADGTATVGITDFAQEQLGDVVYIGVPEMGATVNGGEEAGVAESVKSASDVFSPVTGEVIEINEKLEDEPEIVNEDPYGDGWMFKVKLADEGELEGLMDAAAYAEHVAAEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: THII_TREPA
Sequence: MVNGSTQYLAHVGELSLKKGNRRQFEVQLERNLTLMLRSINPHVTVRAGRLYLSVPASFEAQTTAEQALSYLLGITGWAAATACPKTMEAITRCAHAEATLAAREGKRTFRIEARRADKRFCRTSSEIAREVGAVIHQSGALSVDLHHPDVVIFIEVREREAFLYGARRRGLRGLPCGVSGRGLLLLSGGIDSPVAGYRMLSRGMHIDCLYFHSYPYTPPEAQKKVEDLAKVLARYGLSTTLTVVSLTDIQKQLQTHAPAPSLTLLLRMCMMRIAEHVAREQRARCLITGESLAQVASQTLENLTVTSACTHLPIFRPLIGADKEDIIRTATEIGTYAISIRPYEDCCTLFAPKHPVLRPEVEEMQKQYQSLMLGPLLEDAFRTRKRTRIYGNYGVQESGE
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_XANCB
Sequence: MAKPAEKKTKKKIKRVITDGVAHVHASFNNTIVTITDRQGNALSWATSGGAGFRGSRKSTPFAAQVAAEKAGRAALDYGVKSLEVRIKGPGPGRESAVRSLNNVGYKITNIIDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SC5A8_XENLA
Sequence: MVTPGNIGSFTVWDYLVFALMLLISAVIGIYYAFAGGGQKTSKDFLMGGRSMTAVPVALSLTASFMSAVTVLGTPAEVYRFGAMFIIFAFSYTIVVIISSEVFLPVFYRLGITSTYEYLELRFNKFVRLLGTILFIIQTVLYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTMGGLKAVVWTDVFQVGIMVAGFTSVIIRAVVVQGGIGPILNDSYYGDRLNFWDFDPNPLKRHTFWTIVVGGTFTWTGIYGVNQAQVQRYIACKTRFQAKMSLYVNLIGLWAILACAVLSGLAMYSIYKDCDPWTAKFVSAPDQLMPYLALDILRDYPGLPGLFVSCAYSGTLSTVSSSINALAAVTVEDLIKPYIRSLSEKKMSWISKGTSLLYGAICIGMAGIASLMGGLLQAALSIFGMVGGPLLGLFSLGILFPFVNSLGAVIGLLSGFAISLWVGIGSQIYAPSPSSSLPKPLSLEGCNFTSIESNWTSTVMPMMTTLIPETQVSSRPELADSWYSLSYLYFSTIGTIVAVLVGVIVSLLSGGLKQNVNREFLLTSEDFSYLNVLFSPCKEKGQEEKVEVLNWKARRTDNDMEQGTDNPAFNNMEMTSTEKGEKTNGITA
What is the function of this protein?
Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1.  Catalyzes passive carrier mediated diffusion of iodide.  Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane (By similarity).
What are the official names of this protein?
Sodium-coupled monocarboxylate transporter 1, Electrogenic sodium monocarboxylate cotransporter, xSMCTe, Sodium solute transporter Vito, Solute carrier family 5 member 8.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: BCHL_RHOCB
Sequence: MSPRDDIPDLKGFDGDGEGSVQVHDSEDIGLDVGGARVFSVYGKGGIGKSTTSSNLSAAFSLLGKRVLQIGCDPKHDSTFTLTGRLQETVIDILKQVNFHPEELRPEDYVTEGFNGVMCVEAGGPPAGTGCGGYVVGQTVKLLKQHHLLEDTDVVVFDVLGDVVCGGFAAPLQHADRALIVTANDFDSIYAMNRIIAAVQAKSVNYKVRLAGCVANRSRETNEVDRYCEAANFKRIAHMPDLDSIRRSRLKKRTLFEMDDAEDVVMARAEYIRLAETLWRSTGEPGLTPEPLTDRHIFELLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: PCNA_HUMAN
Sequence: MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS
What is the function of this protein?
Auxiliary protein of DNA polymerase delta and epsilon, is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (PubMed:35585232).  Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities.  Has to be loaded onto DNA in order to be able to stimulate APEX2.  Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways (PubMed:24939902).  Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion (PubMed:24695737).
What are the official names of this protein?
Proliferating cell nuclear antigen, PCNA, Cyclin.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.