PharMolix/UniProtQA huggingface dataset:
Protein: MOAA_HELPJ
Sequence: MLVDSFNRVIDYIRVSVTKQCNFRCQYCMPTTPLDFFDDEELLPLDNVLEFLKIAIDEGVKKIRITGGEPLLRKGLDEFIAKLHAYNKEVALVLSTNGFSLKKMAKGLKDAGLSRVNVSLDSLKSDRVLKISQKDALKNTLEGIEESLKVGLKLKLNTVVMKGVNDDEILELLEYAKNRSIQIRYIEFMENTHAKSLVKGLKEKEILDLIAQKYKIMGMEKPKQGSSKIYTLENGYQFGIIAPHSDDFCQSCNRIRLASDGKICPCLYYQDAIDAKEAIINKDTKMMKRLLKQSIINKPEKNMWNDKNGGTPTRAFYYTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RM08_SCHPO
Sequence: MTKTLYYRKLGRTSAHRQALLRNLVTSLVKHESIQTTWAKAKEAQRFAEKLITMAKRANPQNNRKGLAEGMVFEKETTLKKVFDVLVPRYNGRRCGYTRLLKLPPRSTDNAPMGVLEFVDGPKDIRFHMTAKTVGICLAQQKALTPITRKNIHKVLLFRKNGKAEFDQLVQKEKESEHARLKEDHEDEKTVKKDWKRGDPIPRPTYI
What are the official names of this protein?
54S ribosomal protein L8, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LON_AZOBR
Sequence: MKEAQSMFEIPRGALYPVPPLRDIVVFPHMIVPLFVGREKSVRALEDVMKDDKQILLVTQKNAAQDDPTPADIYSVGTVGTVLQLLKLPDGTVKVLVEGGQRASITKFAENEDFFQAHADLVEEKVGESQELEALGRAVVSQFEQYIKLNKKIPPEVLVSINQIEEPGKLADTVASHLALKIPEKQQLLECATVSERLERVYAFMEGEIGVLQVEKRIRNRVKRQMEKTQREYYLNEQLKAIQKELGETEDGRDESAELEEKINKTRFSKEARDKALAELKKLRSMSPMSAEATVVRNYLDWMLSIPWKKRTKVKKDLKLAQKILDADHYGLEKVKERILEYLRVQNRMNKVKGPIQSLVGPPGVGKTSLGKSIAKSTGRNFVRMSLGGVRDEAEVRGHRRTYIGSMPGKVIQGMKKAKSSNPLFLLDEIDKLGADWRGDPSSALLEVLDPEQNGTFNDHYLEVDYDLSDVMFVCTANTMRMPQPLLDRMEIIRVAGYTEDEKVEISKRHLIEKQVEANGLKKGEFAISDDALRDLIRYYTREAGVRSLEREIANLCRKAVKEILMKGSAGAKVSVTRRNLDKYAGVRRFHFGEAELEDLVGVTTGLAWTEVGGELLSIEAVSLPGKGRVTTTGKLGDVMKESVQAAESYVKSRATAFGIKPTLFEKRDIHVHVPEGATPKDGPSAGVAMITSIVSVLTGIAVRKDVAMTGEITLRGRVLPIGGLKEKLLAALRGGLKHVLIPKDNEKDLAEIPDNVKRGLEIIPVSTVDDVLKHALVREVEPIEWKEPEAVEPAVAKPQTDGGGEVLRH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner (By similarity).  Involved in iron uptake.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_OLILU
Sequence: MSNNVYERNRIKNDRYESGVIPYAKMGYWDANYSVKDTDLLALFRLTPQPGVDPVEAAAAVAGESSTATWTVVWTDLLTACDVYRAKAYRVDPVPSAADQYFAYIAYECDLFEEGSLANMTASIIGNVFGFKAVAALRLEDMRIPYAYLKTFQGPATGIIVERERLDTFGRPLLGATVKPKLGLSGKNYGRVVYEGLRGGIDFLKDDENINSQPFMRWRERFLYCMEGINRASAASGEVKGSYLNVTAATMEEMYERADYAKAVGSVIVMIDLVIGYTAIQSMAIWARKNDMILHLHRAGNSTYARQKNHGINFRVICKWMRMAGVDHIHAGTVVGKLEGDPLMVKGFYDVLRETELSINLPQGIFFEMDWASLRKCCPVASGGIHCGQMHQLVYYLGDDVVLQFGGGTIGHPDGIQAGATANRVALEAMILARNEGRDYVSEGPEILRDIAKLCGPLKTALDLWKGITFNYTSTDTADFVETATSNP
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y833_METJA
Sequence: MFMKSLIKLIVFIVLCSLFLHSICGERTIAEMSITYKLTGEITNTNPYSIFVAVPSNITFEEKTLPKPEDFLDVSTSVTQTSGIVFYKTIFNGKEGFWIPPYTTVKINIYHYTPITYDIKIDESQENYDVVGPAVVNKVNVIDLNKLFPDAKYEGIKIGKFKLYVSGYIVKGNDTESLSIIVPAPLVIDNYDEFHKFGDDNVDIWISSYNEWYKNQMERENIHIDNNDPLIPKMDNDVLGDDTHFKFKIFDVPAMAFTTSSNQPIRFYYIIYYKYNN
What are the official names of this protein?
Uncharacterized protein MJ0833.
Protein: PNPH_PLAFA
Sequence: MDNLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNGAKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLIHGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYPNKIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGILIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKLATKYA
What is the function of this protein?
As part of the purine salvage pathway, catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (PubMed:11707439, PubMed:30602534).  Preferentially acts on inosine and guanosine, and to a lesser extent on 2'-deoxyinosine and 2'-deoxyguanosine (PubMed:11707439).  Also catalyzes the phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine; MTI is produced by adenosine deaminase (ADA)-mediated breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis (By similarity).  Generates hypoxanthine from both the purine salvage pathway and from polyamine metabolism which is required for nucleic acids synthesis (By similarity).  Has no activity towards adenosine (PubMed:11707439).
What are the official names of this protein?
Purine nucleoside phosphorylase, S-methyl-5'-thioinosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family.
Protein: ISPG1_STRCO
Sequence: MTAIPLGLPGVPVRPIAERRVSRRIQVGPVAVGGGAPVSVQSMTTTRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALPVIARKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNIKQFDDKVKEIAKAAKDHGTPIRIGVNAGSLDRRLLQKYGRATPEALAESALWEASLFEEHDFRDIKISVKHNDPVVMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSQGIGDTIRVSLSTPPVEEIKVGIQILESLNLRQRGLEIVSCPSCGRAQVDVYKLAEEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVVKTVPESKIVETLIEEAMRIAEQMEKDGASGAPAVTVS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) 1, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SCF_RAT
Sequence: MKKTQTWIITCIYLQLLLFNPLVKTQEICRNPVTDNVKDITKLVANLPNDYMITLNYVAGMDVLPSHCWLRDMVTHLSVSLTTLLDKFSNISEGLSNYSIIDKLGKIVDDLVACMEENAPKNVKESLKKPETRNFTPEEFFSIFNRSIDAFKDFMVASDTSDCVLSSTLGPEKDSRVSVTKPFMLPPVAASSLRNDSSSSNRKAAKSPEDPGLQWTAMALPALISLVIGFAFGALYWKKKQSSLTRAVENIQINEEDNEISMLQQKEREFQEV
What is the function of this protein?
Ligand for the receptor-type protein-tyrosine kinase KIT.  Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.  KITLG/SCF binding can activate several signaling pathways.  Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1.  KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1.  KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.  KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.  KITLG/SCF acts synergistically with other cytokines, probably interleukins.
What are the official names of this protein?
Kit ligand, Hematopoietic growth factor KL, Mast cell growth factor, MGF, Stem cell factor, SCF, c-Kit ligand.
What is the protein family that this protein belongs to?
Belongs to the SCF family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium. Cell projection, filopodium. SUBCELLULAR LOCATION: [Soluble KIT ligand]: Secreted.
Protein: YGER_ECOLI
Sequence: MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTVKRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSITRKSTAKSTTKTASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYAAGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGSTDAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC
What are the official names of this protein?
Uncharacterized lipoprotein YgeR.
What is the protein family that this protein belongs to?
Belongs to the peptidase M23B family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor. Note=Slightly enriched at the septal ring.
Protein: LEXA_HERAR
Sequence: MIKLTARQEQILNLIRDAIENTGFPPTRAEIAAELGFRSANAAEEHLQALARKGAIEISPGTSRGIRLRDMGGTRSDRSGAQLSLPHPALMQLNLPLVGRVAAGSPILAQEHIEATYNVDKSLFSAKPDFLLKVRGMSMRDAGILDGDLLAVKKIDSAKNGQIVVARLGDDVTVKRYKKTGSLIELLPENPDFQPIRVDLEHDDFALEGLAVGLMRTWN
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SNR27_DANRE
Sequence: MGRSRSRTPPRRERRRSRSSSRDRERRRRERERSRSRDRDRRRSRSRSPHRRRSRSPRRHRSSSLSPLRQKDRRDDDRKDVKEKPAKVHQISAEDMQGKTEEEIEMMKLMGFGSFETSKGKKKDGSIKAFAVNVSQKRKYRQYMNRKGGFNRPLDFIA
What is the function of this protein?
May play a role in mRNA splicing.
What are the official names of this protein?
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein, U4/U6.U5 snRNP 27 kDa protein, U4/U6.U5-27K, U4/U6.U5 tri-snRNP-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the SNUT3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROE_LEGPH
Sequence: MLRRFAVIGHPIAHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLNVTLPYKKRAYELAKIRTQRCTLAGAANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKKILILGAGGAARGIIFPLLEAKPLQLIVANRTLEKAEELQRQFPQINVTSFAELTEFFDLIINATSTSLSGQVIVLPEEVLSHKPFCYDLAYNQKTSTAFVQYARNGGCEAVDGLGMLVEQAAEAFFTWNKVMPSTQKILEHLRSF
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MURB_THEM4
Sequence: MKLIDTLLKLGNDVHINEKMKCHVSFKIGGPVRLFIIPYTVDMFLETLNVLDNVKILGNGTNVLPKDEYMDFNVISTEKLTGIFVENDTIICESGLSLKKLCLYAAKEGFSGFENAYGIPGSVGGAAYMNAGAFGWETAEMIEFVDVYDGKKVLRLDRTEMKFSYRNSIFKENEDLIILRVGFRIIKGDSYNIFSRMKQVMIKRVEKQPLEFPSAGSVFKRPRKGFYVGSAIEKIGLKGFRIGGAMISEKHAGFIINYNNAKSSDVKDMIELVKDKIYKNFGVKLETEIEIW
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQY22_YEAS7
Sequence: MSNESNDLEKNISHLDPTGVDNAYIPPEQPETKHSRFNIDRDTLRNHFIAAVGEFCGTFMFLWCAYVICNVANHDVALTTEPEGSHPGQLIMIALGFGFSVMFSIWCFWWGFEPSRFSLFVFGQSHLTSQMCSDVVSSDHCWDGCWWCR
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes.  Involved in freeze tolerance, osmotolerance and cell flocculation in liquid cultures.  Is non-functional in most laboratory strains (By similarity).
What are the official names of this protein?
Aquaporin-like protein 2, Truncated aquaporin-2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: MAM2_ARATH
Sequence: MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
What is the function of this protein?
Catalyzes only the first methionine chain elongation cycle.
What are the official names of this protein?
Methylthioalkylmalate synthase 2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ESR2_STUVU
Sequence: MSLCTSSHKDFSQLLPLQDIGCNKTEIKNSPAGVISPAPYSCNQSTLTAEHSPVYIPSSYMESRHEYSTMAFCSPAMVNYNIASNFGDPEAVAARQTSSPGALWSAPGHLSPLSLHCQSSLLYAEQPKSLWCEARPMEPVLPGSRETLKRKTNGNDCTSPIANNPGSKKDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMMKCGSRRERCGYRILRSHRGAEERVHCLGRARRYSEAATRVKEILLSTVSPEQFVLTLLEAEPPHVLVSRPSKPFTEASMMMSLTKLADKELVHMIGWAKKIPGFIDLSLYDQVRLLESCWMEVLMIGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLAMTSRFRELKLQHKEYLCVKAMILLNSSMFPLSAEEPESNRKLHHLLNVVTEALVWVIAKSGIPSQQQTTRLANLLMLLSHVRHASNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRGQRKPLATHPEFGPLEQMEPGESLRKGEPQ
What is the function of this protein?
Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.  Locally synthesized estrogens may act via ER beta, in addition to ER alpha, to mediate seasonal or developmental effects on nearby song nuclei.
What are the official names of this protein?
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLO2_SYNP2
Sequence: MEIIRLPAFNDNYIFLLVDRATGDCAVVDPGDAKVVLEYLSKEDLTLKTILITHHHADHVGGNRQLLSHFPAAAVYGSEIDLQKRRIPGQTVSLKAGNHLDLFNRTVEILFVPGHTQGHIAYYFPPLQPEDSGDLFCGDTLFANGCGRLLEGTPAQLFASLQQICDLPDNTNIWCAHEYTLKNIKFSLTVDPENEALQRRFQQVQTQRQRQKPTIPTVLALEKQTNPFLRCSDRQLQANLKTTDPLRVFTKLRGKRDLF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: METN_BORPA
Sequence: MIHIENLSKTYATPHGRFEALRGINLHIQQGEVFGIIGPSGAGKSTLVQCINLLERPDQGSIAIGGQALVGLGEAQLRNQRRRIGMVFQGFNLLARRTVYGNVALPLEIAGVARAEIPARVERLLALVGLEHLRDRYPSQISGGQKQRVGIARALANDPDVLLSDEATSALDPETTHNILALLRDINRKTGVTVVMITHQMEVVREICDRVAVLSHGEVVELGSTREVFAAPRHEVTRAMVSAATASDLSEATLAAVKQRIDALAAAEPGRAVRLWRLSLKGVAAGEPLWSDLAREFALDVSLVQARVEDIQGVAVGTLFVLAQGAPHAVKDALAALAAREITVEEIAHEPATDRSAYHVAA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CMOA_TRIEI
Sequence: MTEPLETELYLSSEKDELFEKGPWPKPFAFNAEVVKVFDNMVCRSVPLYREVVAGAVHWTRAYYQPKTRIIDIGCSTGTFLELLGRFLKQPAILVGIDNSSDMLDKAKEKLAQVEQIHQIELICESAENCSFEKSSVVVMNYTLQFLSLPQRQKLLRAIYQGLVPGGLLFISEKIRSDCPQFQETITHHYEAFKAKNGYAQNEIERKKEALENVLIPLSEAEQLQMLKQSGFSYIESLIKLHNFVSFVAFKSD
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: FBID_AFIC5
Sequence: MARSDAFVILPVKAFVGAKSRLAPLLSVGERTMLARVMLNDVLDAAIAAVGPQSVSVVTSADDVADHARRAGVGVIDDEGARGTNAAVKVGFARIAARRRGAVLTLSSDIPGLIPSDIVALISAAERSRVALAPACDDGGTNALACDVVGRIPLCFGPGSFARHIAAANAADVRPAVLLNQRLGLDLDEPHHLMQFLDRGTSTQTDAYLRVLRLKERKGHSFVVAAQQATGARRLAV
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of (2R)-3-phosphoglycerate (3PG) as 3-[(R)-glyceryl]-diphospho-5'-guanosine, via the condensation of 3PG with GTP.  It is involved in the biosynthesis of a derivative of the hydride carrier cofactor coenzyme F420, 3PG-F420.
What are the official names of this protein?
3-phospho-D-glycerate guanylyltransferase, 3PG guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: RNAS1_CHLAE
Sequence: MALDKSVILLPLLVLVLLVLGCLGRESRAKKFQRQHMDSGSSPSSNSTYCNQMMKRRSMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQTNCFKSKSSMHITDCRLTNGSRYPNCAYRTSPKERRIIVACEGSPYVPVHFDASVEDST
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDPA_BACCZ
Sequence: MIWVAVVITMLLFILVAKPTGIYLEKAFQGSKKLDKVFGPFEKLIFKITGVKEYNQTWKQYALSLVLLNGFMIVVVYFIFRLQGVLPLNPAHIEGMEPTLAFNTAISFMADTNLQHYSGENGLSYLSQLIGITFLMFAAPATTLALVMAFIRGLAGKELGNFFIDFTRALTRVFLPIAFMAALVFVAFGVPQTLDGAVTAQTIDGAKQSILRGPVASFVAIKELGNNGGGFFGANSTHPFENPGQMSNILQMMLMMLLPTALPFTYGRMVGNKKQGRILFVSLFMVFLLGFITITTSELNGNPALNGMGIEHVQGSTEGKEVRFGTVFSSLYATVTTAAETGAVNTMHDTLTPIGGLVPLVNMMLNTVYGGVGAGFVNIIMYAIIAVFISGLMVGRTPEFLGKKIEGKEMKLIAVTILFHPLLILGFSALALSTSLGTDAISHSGFHGLTQVVYEYTSSAANNGSGFEGLGDNTPFWNITTGLVMFLGRYFSLITMLAVAASLKEKTVVPETVGTFRTDNSLFGGIFIGTIVIVGALTFFPMLVLGPIAEFLTLK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSF2_CRYNB
Sequence: MALPKTLHPALTPDELAFLAEHDHISIVPLFSMTRVRLISGIYGPFRPPSASRVPLWLGLSLKKKRKCRIVPPEWLSAERLQAFLRDEKENSEGFERLPRRFMEISKVLLDIASDDLSQPTLLRSLLKDIREVRQAKIRMGLQSEDVLQNDYLQVMPFSSLCPVALRRHLTRYGIGDQSHSLGTV
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.  Has a role in chromosome segregation (By similarity).
What are the official names of this protein?
DNA replication complex GINS protein PSF2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KPRS_CALS4
Sequence: MARYTNSLKIFTGNSNPKLASEIAEHLGLKLADSEVGTFSDGEISVRIGESVRGASVFVIQSTCAPVNNNLMELLIMIDAFKRASAAEINAVIPYYGYARQDRKAKARDPITAKLVADLITAAGAHRVVTMDLHAPQIQGYFNIPVDHLLGGPILAKYFMDKELGDDVVVVSPDHGSVTRARYFAEKLNAPLAIIDKRRPKANVAEVMNIIGDVKGKKAILVDDLIDTAGTLVQAAEALLDHGAVEIYACATHGVLSGPAIERLKESPIKEVVITDTIPLPEEKKIDKIKVRSVAPLFAEAILRIHEGMSVSKLFT
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_GEOMG
Sequence: MTQYEWLQTTLFLVLLLAVVKPMGAFMAKVFQGERTMLSPLLVPCENLLYRICGVNRDEEMDWKRYAVAVLLFNLALFVSLFAILMLQHLLPLNPQKFPAYTWQLALNTAISFVTNTNWQAYSGESAASYFTQTVGLAVHNFVSAATGIAVAIAVIRGFARRRTSMLGNFWVDMTRCTLYVLLPISLIGALILVSQGVIQNFSDYKTVPLVQPITYDKPKADGKGNPVTGRVTVKDITIPMGPVASQEAIKELGTNGGGFFNANSAHPYENPTPISNMVEIFLILLIPFALTSTFGVMVGNTRQGWAILGVMLLMMAISFAVLQGVETSGNPLVAKLGVHGVNMEGKEVRFGLAGASLFTVATTGTSCGAVATMHDSLTPLGGMIPLGLILLGEIAPGGVGSGLYTMLAFVVIAVFVAGLMIGRTPEFLGKKIEVREMWMSIITVLAAGVVVLILSGVAMITPQAVASKANPGAHGLSEVLYAFASMANNNGSAFAGLNANVDFYTILGSLAMLVGRFAPAVAVLAMAGSLAEKKYVPPSLGTLPTDKVPFALWLMLVILIVGALTFFPALSLGPLVEHLTMLGGK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MISSL_HUMAN
Sequence: MSDEFSLADALPEHSPAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMPGGPHSYH
What are the official names of this protein?
MAPK-interacting and spindle-stabilizing protein-like, Mitogen-activated protein kinase 1-interacting protein 1-like.
What is the protein family that this protein belongs to?
Belongs to the MISS family.