PharMolix/UniProtQA huggingface dataset:
Protein: RES1_SCHPO
Sequence: MYNDQIHKITYSGVEVFEYTINGFPLMKRCHDNWLNATQILKIAELDKPRRTRILEKFAQKGLHEKIQGGCGKYQGTWVPSERAVELAHEYNVFDLIQPLIEYSGSAFMPMSTFTPQSNRKPTEAYRRNSPVKKSFSRPSHSLLYPYTSSNNMTSTSRMSGIHDALSLQSDFTRSPDMPSDSFTGSLHDIKASPFSSNNYAQSLLDYFLLPNTTQPPDFVYDRPSDWDVNAGIDEDGHTALHWAAAMGNLEMMHALLQAGANVVAVNYLQQTSLMRCVMFTMNYDLQTFEVVSELLQSAICMNDSFGQTVFHHIALLASSKSKMEAARYYMDILLQNLTATQSVDVAAQIINLQDDHGDTALLICARNGAKKCARLLLSFYASSSIPNNQGQYPTDFLSSKDMSFPENDDSPLNSKIEDNLIDNLKYPQSLDDHLSSKKPISYFSNKLTHQTLPNVFTQLSELSKCHEASLAEKQLTYNLAMEALEQTVRETETCQRLWNERTNNDENYLVNQREDLIHQCKKFLHTLKTARYYLETVQLHQLKKYVTYFSQIWSTDELADISETKNLVGHDTKTNRSSLSSKHEVDLFTAENEAAREKLVEQLCSLQAQRKQKINEILNLLSMGMYNTINTDQSGS
What is the function of this protein?
Acts as a positive regulator of the mitotic cell cycle and as a negative regulator of sexual differentiation.  May be involved in the transcriptional regulation of the cdc22 and cdt1 genes.  Is an integral component of the DSC1-like complex.
What are the official names of this protein?
Cell division cycle-related protein res1/sct1, p72sct1.
Protein: PERR_STAAS
Sequence: MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
What is the function of this protein?
Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins.  May act as a hydrogen peroxide and organic hydroperoxide sensor (By similarity).
What are the official names of this protein?
Peroxide-responsive repressor PerR.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODBA_BOVIN
Sequence: MQGSAKMAMAVAVAVARVWRPSRGLGRTGLPLLRLLGARGLARFHPHRWQQQQHFSSLDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEKVLKFYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDDTDLVFGQYREAGVLMYRDYPLELFMAQCYGNVSDLGKGRQMPVHYGCRERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGILSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHHLQSRGWWDDEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLIFSDVYQEMPAQLRKQQESLARHLQTYGEHYPLDHFEK
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial, Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain, BCKDE1A, BCKDH E1-alpha.
What is the protein family that this protein belongs to?
Belongs to the BCKDHA family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SPED_ECO5E
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: MNMA_CLOBB
Sequence: MGLTKKKVLVGMSGGVDSSVAAYLLKEQGYEVIGATMQIWQEDKEVEEREGGCCSLSAVEDARRVCDKLDIPFYVLNFRDSFKKKVIEPFIQEYIDGRTPNPCIECNKHLKFDELLRKAQGIGVDYIATGHYAKIDKKDDRYMLIRSDDDRKDQTYALYNFTQDQLAHTLMPCGEYTKDRIREIAKEIGLAVHNKKDSEEICFISDNDHGKYILNAKPGAVKSGNFVDKSGNILGKHKGIVYYTIGQRKGLGLSVGRPVFVTDINPKTNEVVIGAEEDIFKTELIAGDLNFITFDKLEKEIEVEAKIRYSARPGKATIVPLKDGRVKVVFNEKQRAITKGQSVVFYNGNIVIGGGVIEAII
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTN1_HUMAN
Sequence: MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT
What is the function of this protein?
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response.  Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK.  May play an important role in CKII- and p60c-src-induced signal transduction cascades.  May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion.  May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Interacts with EPHA3 at the cell membrane.
Protein: RS14_ERYLH
Sequence: MAKLSSINKNEKRKKLVKQYAAKYEKLKAIANDKSLDETERLIARLKMAEIPRNANPTRVRNRCATTGRPRGYYRKFGINRIELRDLGNKGLIPGLTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TTGV_PSEPT
Sequence: MNQSDENIGKAGGIQVIARAASIMRALGSHPHGLSLAAIAQLVGLPRSTVQRIINALEEEFLVEALGPAGGFRLGPALGQLINQAQTDILSLVKPYLRSLAEELDESVCLASLAGDKIYVLDRIVSERELRVVFPIGINVPAAATAAGKVLLAALPDETLQAALGEQLPVLTSNTLGRKALVKQLSEVRQSGVASDLDEHIDGVCSFATLLDTYLGYYSLAIVMPSSRASKQSDLIKKALLQSKLNIERAIGRASKKAP
What is the function of this protein?
Represses the expression of the ttgGHI and ttgVW operons.  Binds to the ttgGHI / ttgVW intergenic region, probably preventing binding of RNA polymerase; ttgV dissociates from this region in the presence of 1-hexanol.
What are the official names of this protein?
HTH-type transcriptional regulator TtgV, Toluene tolerance pump ttgGHI operon repressor.
Protein: RF3_CUPTR
Sequence: MSSLVSEIARRRTFAIISHPDAGKTTLTEKLLWFGGAIQVAGEVRARKADRHATSDWMELEKQRGISVTSSVMQFPYSRESADGKAQENIVNLLDTPGHEDFSEDTYRTLTAVDSAVMVIDSVNGVEAQTIKLLNVCRLRDTPILTFINKLDREGRSPIELLDEIEDVLQIQCAPMTWPIGMGKAFRGVYHLIDDKVQLFDPHGDKGTAAILDGLDNPELDRILGSQAEELRIEIELVRGASHTFDKAAFLNGKQTPVYFGSAINNFGVQSLLDALCELSPPPLARNTESRVVEPQEPKFTGFVFKIQANMDPRHRDRIAFVRVCSGRFERGMKLLHVSAGKTVAINNAITFMAQDRNTTEEAYAGDIIGVPNHGTIRLGDVFTEGEPLKFTGIPSFAPEFFRRARLNNPLKVKQLQKGLQQLAEEGATQMFRPLASNDLVLGAVGILQFDVVAHRLEHEYGVDAIFESHECATARWLKGTPAEIEKLIAKAGHNVALDGAGDHVYLAPSMVNLRLTQERFPELQFLETREIV
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P20D1_CHICK
Sequence: MAGGCGRRRVVVCAVALGLSAAVLALTAVVLLRAYVLRSPAIPRLWARRGSTAAFSASERRELKEALRGAVRIPTVSLSSEDFNTTAMAEFGDYIRKAFPAVFSSKFIQHEIIGEYSHLFTVQGSDSEMMPYMLLAHMDVVPAPPEGWDFPPFSAAEHEGFIYGRGTLDNKNSAIGILQALEFLLRRNYRPRRSFYVGIGHDEEVFGQKGALKIAALLESRGVKLSFLLDEGSAILDGIIAGVKKPVALIAVTEKGLMTLNFTVEKEPGHSSFPPKETSIGILATAVSRLEQNPMRSLFGRGPELMTMEHLASEFNFPLNLIMSNLWLFSPIVSRVLAWKPSTNALIRTTTAVTMFNAGIKFNVIPPSARATVNFRIHSGEKAKEVLETVRNTVADDRVKIDVIEALDPLPISPWDDQTFGVHVFQRTILDTFPNVDSVVPGTCIGNTDSRHFTNVTNAIYRFNPVLLKSDDLPRIHGLNERISVESYEKQVEFLFQLIKNCDVDKLPEPHANSHEL
What is the function of this protein?
Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase.  It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction.  Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1-independent manner.  Thereby, this secreted protein may indirectly regulate whole body energy expenditure.  PM20D1 circulates in tight association with both low- and high-density (LDL and HDL,respectively) lipoprotein particles.
What are the official names of this protein?
N-fatty-acyl-amino acid synthase/hydrolase PM20D1, Peptidase M20 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVC_RHIE6
Sequence: MQNTIRIVGIDPGLRRTGWGIIDTLGNSLRFVASGTVTSDGDMDLASRLCQLHDGLAEVVHAYKPDEAAVEQTFVNKDAVATLKLGQARGIAMLVPARAGLHVSEYAPNAVKKAVIGVGHGEKHQIHMMLKILMPKVEFKGDDAADALAIAICHAHNRGSNRMRQALAG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: HIS5_PROMT
Sequence: MTKIGLIDYGMGNLFSVQQAFKRFNQPLDIISDIKTLQSCDALILPGVGAFDPAMMNLRKTELVPSIIDWVNNGKPLFGICLGLQLLFEASDEGTSEGLGVIKGHIRRLPQEKDERIPHIGWSPIYKTNECPILENYPGSNWMYFVHSYSACPLEPKHTVAVTKFGKTDVSSMVWHKNTGACQFHPEKSGVAGQKIIFNWINWLKKNKF
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARN_XENLA
Sequence: MEITRSNFKDTLPKVYKAIEEADFLAIDGEFSGISDGPSVSTLTNGFDTPEERYTKLKKHSMEFLLFQFGLCTFNYDNTEAKYLMKSFNFYIFPKPFNRNSPDKKFVCQSSSIDFLANQGFDFNKVFRNGIPYLNQEEERVLRDQYEDRRSQSNGASTMSYISPNSSKTPVSIPDEQKGFIDKVVERVEDFLKNEQKSMNVEPCTGYQRKLIYQTLNWKYPRGIHVETVESEKKERYIVISKVDEEERKRMEQQKQAKEREELDDAVGFSRIIQAISSSGKLVVGHNMLLDVMHTIHQFFCQLPDELNEFKEVTNCVFPRVLDTKLMASTNPFKEIIYNTSLAELEKRLKEAPFKPPKVDSAEGFQSYNTASEQLHEAGYDAYITGLCFISMANYLGSFLSPPKDYVSCRSKIVRPFFNKLFLMRIMDIPYLNLEGPDLQPKRDNVLHVTFPKEWKTSDLYQLFSAFGNIQVSWIDDTSAFVSLSQPEQVQIAVNTSKYAESYRIQTYAEYIEKKNDESQTKRKWAEDGWKDLERKRLKTQYNSYIPQNPVFYGNCFAPSFAVKRSMSPIQEEAASDDTEEVHTHENDPSNPGATEQGKKPKNHKRQKIDSAPPETSDGGSSVLFEVPDTW
What is the function of this protein?
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails.  Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs.  Required during meiotic maturation to silence certain maternal mRNAs translationally.  Does not require an adenosine residue at the 3' end, however, the addition of 25 non-adenylate residues at the 3' terminus, or a 3' terminal phosphate is inhibitory.  Involved in dormant mRNAs regulation during oocyte maturation by counteracting polyadenylation mediated by papd4/gld2nt in immature eggs.  During maturation it is excluded from the ribonucleoprotein complex, allowing poly(A) elongation by papd4/gld2nt and activation of mRNAs.
What are the official names of this protein?
Poly(A)-specific ribonuclease PARN, Deadenylating nuclease, Deadenylation nuclease, Polyadenylate-specific ribonuclease, parn-A.
What is the protein family that this protein belongs to?
Belongs to the CAF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PGXC_ASPFN
Sequence: MLITKTAFLAFLLSSVPLAHGAGGNSSSPDARGRRCVVRSSNGTADDSPEVSRVFAQCATNSVIVFQEGVDYNIFQPIKATNLSNVEIQMHGNLHLPQNISAVRDIVNAGTSTWFTLEGPRVDWTGPEDVNNGWIKSYGQAWWDANPPNGTGISGRPHLMSYKTSQATIKYFRSGKPIAWNMKLHGEDIAVSHAIVDASSTGSFPFNTDAFDVQGTNIRISDSIMYNGDDAIAVGSDSHNIVFERNTIGYQSHGMSIGSLGKDASAFANITNLRFEDVTVIDALYAARFKSWTGGQGLVKNVTWKNIRVYNVTFPIFVTQSYYDQSVSRDGVDTESSVMMEDFTWEDFSGSINSYQPGDGSCATDPCWYNAGLPNLKHTEALVIECNTDKSCKNFVTKNIQLYPQVLEPASVICMKATAELNPNLGFNCSNGTFTSA
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Probable exopolygalacturonase C, Galacturan 1,4-alpha-galacturonidase C, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BEPC_BRUSU
Sequence: MRYTVFKACKELVAAAVLLSGTVLTGQAALSETLTGALVKAYKNNAPLNSSRAGVRIQDENVAIAKSAYRPQITGSYNISRGKTPATDYRTTGTVGIQLNQMLFDGFQTRNNVAAAETQVFAQRENLRNDEQNTLYQAVAAYMDVYQLRQIAALREKNLAAMNEQVRAARARLDVGEGTRTDVAQAEASRSTAIAALNAARADVKTAEATYMQVVGSLPDKLTPASAARHLPQSPSQAYASALASHPGILATKYAVNAAGYNVKAKEGALLPTIGLTASASQLDTIAGTDMGDGNTASIGVGVNIPIYTGGRTSAQIRQSKEQLGQARIEVDVVQDKVRQAISSAWSQLEAARASVAANRDGIAAAQLALDGVIEERKVGQRTTLDVLNAQNDLVAVQIALVQAEHDVVVASYALLNATGRMTADQLGLQVAQYKPEEHYKAVKDKWFGLRTPDGR
What is the function of this protein?
Involved in the efflux of toxic and relatively hydrophobic compounds.  Influences survival inside the host.
What are the official names of this protein?
Outer membrane efflux protein BepC.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS19_BREBN
Sequence: MGRSLKKGPFVDDHLMKKVDEQNEKNEKRVIKTWSRRSTIFPDFVGHTFAVYDGRKHVPVYVSEDMVGHKLGEFAPTRTFKGHVDNDKKSKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CYB_FOSFO
Sequence: MTNIRKSHPLIKIINESFIDLPAPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGMYYGSHTFSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGLTSDSDKIPFHPYYTIKDILGLLLLILILMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVTALVLSILILAILPLLNTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASILYFLTILILMPISGMIENQLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YAII_ECOBW
Sequence: MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATIRERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG
What are the official names of this protein?
UPF0178 protein YaiI.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: ERR2_RAT
Sequence: MSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGMALGTHANGLDSPPMFAGAGLGGNPCRKSYEDCTSGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSENSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPDDVPEGDIKALTTLCDLADRELVFLISWAKHIPGFSNLTLGDQMSLLQSAWMEILILGIVYRSLPYDDKLAYAEDYIMDEEHSRLVGLLELYRAILQLVRRYKKLKVEKEEFVMLKALALANSDSMYIENLEAVQKLQDLLHEALQDYELSQRHEEPRRAGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV
What is the function of this protein?
Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcription activity (By similarity).  Plays a role, in a LIF independent manner, in maintainance of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways.  Upon FGF signaling pathway activation, interacts with KDM1A by directly binding to enhancer site of ELF5 and EOMES and activating their transcription leading to self-renewal of trophoblast stem cells.  Also regulates expression of multiple rod-specific genes and is required for survival of this cell type (By similarity).  Plays a role as transcription factor activator of GATA6, NR0B1, POU5F1 and PERM1 (By similarity).  Plays a role as transcription factor repressor of NFE2L2 transcriptional activity and ESR1 transcriptional activity (By similarity).  During mitosis remains bound to a subset of interphase target genes, including pluripotency regulators, through the canonical ESRRB recognition (ERRE) sequence, leading to their transcriptional activation in early G1 phase.  Can coassemble on structured DNA elements with other transcription factors like SOX2, POU5F1, KDM1A and NCOA3 to trigger ESRRB-dependent gene activation.  This mechanism, in the case of SOX2 corecruitment prevents the embryonic stem cells (ESCs) to epiblast stem cells (EpiSC) transition through positive regulation of NR0B1 that inhibits the EpiSC transcriptional program.  Also plays a role inner ear development by controlling expression of ion channels and transporters and in early placentation (By similarity).
What are the official names of this protein?
Steroid hormone receptor ERR2, Estrogen receptor-like 2, Estrogen-related receptor beta, ERR-beta, Nuclear receptor subfamily 3 group B member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome.
Protein: RS2_SALSV
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKISARKGKILFVGTKRAASEAVKEAANSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVSLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RED1_YEAST
Sequence: MEGLKKKIFGVCLKNDLAQTRNETKGIHYGLMTLETSKQLQEFLHLLVIKREVIQNFELLFHIINVAVKITDSNLPSDDIWHFILKLRFSSEINIDEDSKVLNYLLETGIAMENPVSWKCLAVISSILSSVPQSKKIITNLIETEHAKKIGQLFDNIQDLQQGNFLVEILSNCFKKSASNSKKVEKIPQLWQSRSKNKFFFENEFYPFSSKNGSLQTCQFLCNNFMSTLSFTGILRQVSYSGSETLKNLRIFKKKDDENSYFIQCIYNKIYLWLDEKAPLEFERKKIRITKNLKNKIQIKLRQPFHECVRTTADKTALLFNKTKGFQLEFEDEKLGETFFHNVNNIPKISEVQNFLVLDYIEEEPENEGEEEEQIGRADEQKEDEEEESLDELSTPMVYPIKSSIPHNHNEKVQLVTPDRSVSIRSDEWDLKSNTEDEEGNVLADLKISSTKETKRQTDYVHIDSEDQSPVVSAQMRKMRRESTKTLEILRQEFKDKDVQNKEDQSEQIQNPFVNTSSLVVGKSCLVNPKEKPNIDQTVVGITELKSNSSIKKRDINILDTIFGQPPSKKQKQFHKKEKKKQQKKLTNFKPIIDVPSQDKRNLRSNAPTKPKSIKVSKLRTDKKVTGEKSSPETAAEKVDDQTVRSNDEQAMSRATKEKCFPDVNEGKEITKDDAKVSLESKKNNETFVDSSVVEKHTPPDKDCNNCNITDILESTTVIDLQSPHGLSAPGQNTFTNKLQEQIYSSINHFSNELVRKISIINQELNKKILKELSEKYQKLFSELQDNFQNDTNEMLKFMGEIKDMMNLPEDQLVHAIRTRKFDNNKR
What is the function of this protein?
Probable constituent of the synaptonemal complex during meiosis.  May interact with HOP1.  Required for meiosis I chromosome segregation.
What are the official names of this protein?
Protein RED1, Reductional division protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: YQGF_CHLAB
Sequence: MSNPQVAKVFLGVDYGERRIGLAYAAYPLGISLPIGFIATGKTLEATAKLLVGIIQERRVSTVVLGNPLPMQKGQKSALQEDILKLSSLLQESCPVEVILWDERLSSAQAERMLKGDCGLSRKKRKGKTDSIAATLILTSFLEHSPRLPS
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WFD12_PANTR
Sequence: MGSSSFLVLMVSLTLVTLVAVEGVKEDIEKAGVCPADNVRCFKSDPPQCHTDQDCLGERKCCYLHCGFKCVIPVKELEEGGNKDEDVSRPYPEPGWEAKCPGSSSTRCPQK
What is the function of this protein?
Antibacterial protein.  Putative acid-stable proteinase inhibitor (By similarity).
What are the official names of this protein?
WAP four-disulfide core domain protein 12.
What are the subcellular locations of this protein?
Secreted.
Protein: IDH_HELPY
Sequence: MAYNPKILQKPKEGEEITIKDNKLHVPNHPIIPFIEGDGIGSDITPAMIKVVDSAVQKAYKGEKKIAWYEVFVGEKCYQKFKDYKELSPEEQWLLPDTIEAINHYKVSIKGPLTTPIGEGFRSLNVALRQKMDLYVCLRPVRWYGSPSPVKEPQKVDMVIFRENSEDIYAGIEWQEGSAEAKKLIHFLQNELKVKKIRFPESSGIGVKPISKEGTERLVRKAIEYAIDNDKPSVTFVHKGNIMKYTEGAFMKWGYALAQKEFNAQVIDKGPWCSLKNPKNGKEIIIKDMIADAFLQQILLRPSEYSVIATMNLNGDYISDALAAMVGGIGIAPGANLNDTVGMFEATHGTAPKYAGLDKVNPGSIILSAEMMLRHMGWVEAADLIVSAMEKAIKSKKVTYDFARLMDGAKEVKCSEFASVMIENM
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: RS19_FRASN
Sequence: MPRSLKKGPFVDDHLLKKVDVQNEKGTKHVIRTWSRRSTVIPDMLGHTIAVHDGRKHVPVFITEGMVGHKLGEFAPTRTFRGHVKEDRRSRRG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.