PharMolix/UniProtQA huggingface dataset:
Protein: RL17_FRACC
Sequence: MPTPTKGARLGGSPAHERLLLANLATALFEHGGITTTEAKAKRLRPYAERLVTFAKRGDLHARRRVMRQVRDNSVVHTLFTEIGPRYANRNGGYTRIVKIGNRKGDNAPLARIELVEALTVGQQAVSEAERARGTRFEARRKPTGATVEAAEELAQESPTAAAVAVEAAEPAETPAEGAAGKPTTAQTDDSGIGDDSGAGEQNSAN
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GP13_BPMU
Sequence: MENNKTSYSWLGKFTTVKQECPTCGNESPEYLKECPHCGGLKCNHCDMGDDTACMNCEGE
What are the official names of this protein?
Uncharacterized protein gp13, E14, Gene product 13, gp13.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RIDA_DERFA
Sequence: MSPKRIISTPLAPQPIGPYSQAVQVGNTVYLSGQIGMNVRTNEMVTGPIRDEAQQAFTNMKAVVEASGAKMSDVVKVNIFIRNFNDFPAINDVMKEFFQSPFPARSTVGVAELPKNARVEIESIVVIE
What is the function of this protein?
Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism (PubMed:27539850).  May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components.  It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase (By similarity).  Preferentially digests Leu and Met in cooperation with L-amino acid oxidase, but digests Phe poorly (PubMed:27539850).
What are the official names of this protein?
2-iminobutanoate/2-iminopropanoate deaminase, Allergen Der f 34, Enamine/imine deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHJ_ECO45
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAVSTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MCH_HALHT
Sequence: MTDWTDPDALDLSDGETFDSLLDRADTREKGHFFEFFAEGDELAHDPGLRLSHHGSEQWMGQTLNHDPAYWRADTAQERGFEERPVHPDYLLACVMGITVEDLSEKGGYFLGRDDVEFHQPATAGTPLSVTSTVVDTRTSSSRPKYGIVTWETEGRDRETGETLVSYRRTNMIPRREPAATDGGAVGEQDEGGPAMPDTLLSPDGERFGDFQAALDTAREENAAVAYRHERGRTMDDQLVAGLPLSTLNTARQHHNRDEMADSPSGDIVAYGDVTRSIALAHARSDEATYREQRFADERFHDFVTLGDTVYGFTRVLDCDPDAGPERAGAVTFEHVAFNQEQTPVYSGRRTAHIQRHQ
What is the function of this protein?
Involved in the methylaspartate cycle.  Catalyzes the reversible hydration of mesaconyl-CoA (2-methylfumaryl-CoA) to yield beta-methylmalyl-CoA ((2R,3S)-beta-methylmalyl-CoA) (PubMed:28932214).  Shows also activity with mesaconyl-C4-CoA (3-methylfumaryl-CoA), (S)-citramalyl-CoA and (S)-malyl-CoA (PubMed:28932214).
What are the official names of this protein?
Mesaconyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: TX31E_SCOMU
Sequence: MKSSMAILLVMALIIFTLDKNYSTAKDLPSCEKGIHRKVTCKQCNKRSDNDDDYTKCCNSFDAFLMCGFLLSKES
What is the function of this protein?
Inhibits voltage-gated potassium channels.
What are the official names of this protein?
Kappa-scoloptoxin(03)-Ssm1e, Kappa-SLPTX(03)-Ssm1e, Kappa-scoloptoxin-Ssm1e, Kappa-SLPTX-Ssm1e.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-03 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VSPA1_CROAT
Sequence: VIGGDECNINEHRSLVAIFDS
What is the function of this protein?
Snake venom serine protease that completely cleaves fibrinogen Aalpha chain (FGA), partially cleaves Bbeta chain (FGB) and has no activity on gamma chain.  Is more potent that A2 and A3 alpha-fibrinogenases.  Very active within 5 minutes.
What are the official names of this protein?
Alpha-fibrinogenase A1, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RECF_AGRFC
Sequence: MMTNKVSLSRLKLTDFRNYAAAALVLDERHVVLTGDNGSGKTNLLEAVSFLSPGRGLRRAVLSDVTRVGAEATGFSIFADVDGMDGEVAIGTGIEGDGEVVSRRLRLNGTPVKSVDELTDHLRVLWLTPAMDGLFTGSSSDRRRFLDRLVLSLDPGHGRRASDFEKAMRGRNRLLSEGRFDPVWLDGIEKQMAELGISMAVARYEMLGLLKTLIEGRAGNAAFPSATLSLAGFMDDRLNRPAVDLEDEYGLMLRDGRYRDAAAGRTLDGPHRVDLFVRHAEKNMEAERCSTGEQKALLVGLVLAHAQLTANMTGYAPVLLLDEIAAHLDEGRRAALFDLIHALGGQSFMTGTDAAMFSALGERAQFFNVSHGGITA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AEPH_PECCC
Sequence: MGQEPKGIESRKIQDGHVRKKVGRQQGLWVRTTKKEKFSRMSRDANV
What is the function of this protein?
Involved in the control of extracellular enzymes production.  Stimulates PEL, PEH, CEL, and PRT production.
What are the official names of this protein?
Exoenzymes regulatory protein AepH.
Protein: APOE_ORCOR
Sequence: MKVLWVALVITLLAGCQAEVEPEPEPEVQLGREWPRWQGSQPWEQALGRFWDYLRWVQTLSDQVQEELLSTQVIQELTVLMDETMKEVKAYREELEGQLGPIAQETQARVSKELQAAQARLASDMEDVRSRVAQYRSEVQAMMGQTTDELRGRLASHLRKLRKRLLRDAEDLQKRLAVYRAGALEGSERSVSAIRERLGPLVEQGRVRAATVGTLASQTLRERAEAWHQKLRGRMEEMGTQARDHLEEMREQLEEVRAKVEEQGSQMRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQLAMATSPTSAPIENS
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: SERB_PONAB
Sequence: MVSHSELRKLFYSADAVCFDVDSTVIREEGIDELAKICGVEDAVSEMTRRAMGGAVPFKAALTERLALIQPSREQVQRLIAEQPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVASKLNIPATNVFANRLKFYFNGEYAGFDETQPTAESGGKGKVIKLLKEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNVIRQQVKDNAKWYITDFVELLGELEE
What is the function of this protein?
Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine.  L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator.  May also act on O-phospho-D-serine.
What are the official names of this protein?
Phosphoserine phosphatase, PSP, PSPase, O-phosphoserine phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. SerB family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SPIR_DROME
Sequence: MTEHQAEEQADTPPTKVKATPTPTPSGKFKDAKEDAFLSTSPDSANGDAQHKLPADQLAMSSSAHPQQAGQARPLILQAFHRCSSPEQCVTLHDILDSFKAPLSEDQAWALIHQFAGLYHQVAVQAHTCAADYEAALPTGFELHFHRDGSVHFSGPDQLTPKEQLQQEQIPLPPQHDVIVDQPDHSASSSGDSSVINRAFDNSNHHHHHQHHHPPLVVSHRKIISELAEIVYTALDYNLPEDEECQVSQELENLFNFMTADETDDDCIDEGIDEGDKRWDDESEEERNDTKELEHIIETCRNHIKTTLPENHYRAVCRALVTETIELRVFLQQVLNNEAGAEKLIKASESSATTQQELAKLGFNDWARFWVQVIDELRRGVRLKKSNHERTPIEYELTPYEILMGDIRAKKYQLRKVMVNGDIPPRVKKDAHAMILEFIRSRPPLKKASDRQLGPPRMCEPSPREQLMESIRKGKELKQITPPEAPTLRERVLPSANSTLSRSRQRLIKVDFSKFQDDDLFYDENSISSSHSTAATHQHHPHFAEMHRCSQPKMPPYPFGGYMVPSQARQDCRETASLMRPRRTMEPAKQVPPPEEPSFTKDEYHKFYDTALESYDLATQCESRRASLRRHTIVGCQSNLDETHSMPPTRPESRQSDDVSKETPKRSPAEQTHPSDEGSSTSSLGPWNKSFMDKQTWMERGDDRLSVTLAEIVHIRSVMTKAELEGLPMDVRVKEDVEKRRVCFLCLRTRFSFFGPWGIQCKLCQRTVCAKCYTKMRIPSEHFRNVPLVLISPSLLSSPASSSTPSPSHHAQQAHSSSTGNIMDDQFPKSLIERLLRSESDRKTRSTVGSAPSSPKHQRSNMSTPGISVGPGASSSSAAATGQAVEALHDQATMSSSYSAAMRPSGVHQQQKQHYNNAMSRSMEGPRSLPVHSPAYRPLSNNSTLERKSRFSRGFNLFSSGSHLAQTQEQKENLRGEQVTVCNDCQGLVNEITSSVKQKRSSARNRTIQNLTLDLTPVWK
What is the function of this protein?
Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament.  Promotes dissociation of capu from the barbed end of actin filaments.  Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport.  Required for localization of determinants within the developing oocyte to the posterior pole and to the dorsal anterior corner.  Links Rho family signaling and Jnk function to the actin cytoskeleton.
What are the official names of this protein?
Protein spire.
What is the protein family that this protein belongs to?
Belongs to the spire family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Punctate spots in perinuclear region and cytoplasm.
Protein: HGD_BURO0
Sequence: MTLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFEPYAGAQRLVSEFGDSADVPPTPPNQLRWDPLPMLVEPTDFVDGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGELLIVPQQGRLFIATEFGRLDVEPFEIAVIPRGVRFAVALPDGDARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQAAYEDREGAFELIAKLNGRLWRADIGHSPLDVVAWHGNYAPYKYDLRLFNTIGSISFDHPDPSIFLVLQAQSDTPGVDTIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDATMAFMFETRTLIRPTCYALDTAQLQADYFECWQGIKKHFNPEQK
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: Y281_PYRHO
Sequence: MRIGKRRKMSGELRVRRVSSWEFDLILREAEKYGELSHEFFSIVEGEYRDVYAVNESVWKLVEKLPLKPYSLGTFVGTIRVDDNLVEKFYPNIEFFSLVKVTKNYAVLGPKASFLFTTGKDVPKRAVKKLNWQGSRKILIYNDLGDIIGIGMINPRNDEKFIKNLKDVGEFLRR
What are the official names of this protein?
UPF0113 protein PH0281.
What is the protein family that this protein belongs to?
Belongs to the UPF0113 family.
Protein: CSPL2_LOTJA
Sequence: MKVSAVETGEISQVSAPRKGMIRGLSIMDFILRIVAAIGTLGSALSTGTTRETLPFTTQFVKFRAVFDDLPTFVFFVTSNSIVCGYLVLSLALSFFHIIRRSSAAKSRILLVFLDTVMFGLLTTGAAAAGTIVYVSHYGNVNANWFPFCGQYNHFCERISGSLIGSFIAVVIFMIIILMSAVSISKH
What are the official names of this protein?
CASP-like protein 2, LjCASP2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPB_NYPFR
Sequence: MRTNPTTSSPVVSTLEEKNLGRIAQIIGPVLDVVFPPGKMPNIYNALAVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKFSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRVLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MDTH_YERPG
Sequence: MALVSQARSLGKYFLLFDNLLVVLGFFVVFPLISIRFVDQLGWAALVVGLALGLRQLVQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFALMAMADEPWILWLACALSGLGGTLFDPPRTALVIKLTRPHERGRFYSLLMMQDSAGAVIGALIGSWLLQYDFHFVCWTGAAIFVLAAGWNAWLLPAYRISTVRAPMKEGLMRVLRDRRFVTYVLTLTGYYMLAVQVMLMLPIVVNELAGSPAAVKWMYAIEAALSLTLLYPLARWSEKRFSLEQRLMAGLLIMTLSLFPIGMITHLQTLFMFICFFYMGSILAEPARETLGASLADSRARGSYMGFSRLGLALGGALGYTGGGWMYDTGKTLDMPELPWFLLGIIGLITLAGLYWQFNRRRIESAMLSSS
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS19_ANASK
Sequence: MARSIKKGPFADKHLTKKVEDANKGNKKSVIKTWSRRSTILPDFVGHTFAVHNGRKFVPVFVTENMVGHKLGEFAPTRTFHGHSAEKKAAAAPAPAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GLUC1_PETMA
Sequence: MSDPGFLAAPVLLLLLVSLASASLEQAASRDDDSAERPLSKRHSEGTFTSDYSKYLENKQAKDFVRWLMNAKRGGSELQRRHADGTFTNDMTSYLDAKAARDFVSWLARSDKSRRDGGDHLAENSEDKRHAEDVNALLDRTMAKTFIEWLEKQNSNDQTD
What is the function of this protein?
Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level.
What are the official names of this protein?
Glucagon-1.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARLY_PARL1
Sequence: MSNKMWGGRFGEGPDRIMEEINASIGFDQRFFAQDIRGSKAHCRMLAEKGIISSEDAAQIVAGLDVVLAEIENGTFHFKRELEDIHMNVESRLADLIGAAAGRLHTARSRNDQVATDFKLYIRDTIDHLDEQLADFQRALVDRAEEHAATIMPGFTHLQTAQPVTFGHHCLAYAEMAGRDRGRLADARRRLNESPLGAAALAGTSFPIDRHMTAAELGFDGPTRNSLDSVSDRDFVLETLSAAAIAATHLSRLAEEIVIWSTPGFDFVRLTDGFTTGSSIMPQKRNPDAAELVRAKSGRVIGDLTSLLIVMKGLPLAYSKDMQEDKEAAFDALDALSLSLAAMTGMVRTLTVNETAMRNAASRGFSTATDLADWLVRALGLPFRQAHHATGALVAKAEKKGTDLDGLTLAEMQEVEPGITDEVYSVLGVDNSVASRTSFGGTAPDNIRAAVRRWRDELGS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_LACP3
Sequence: MDLELFDDDQLLDDKHHDLIKKLVAFCGKQLKLPENTEMSITLVGDDEIERINREYRETDRVTDVISFAIEEGEDDLPLLPGMAKNIGDLFIDPLTVRRHAEDYGHSFERELGYTVVHGFLHLNGYDHIKPEDEAVMIPLQKKILAAYGLTR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODO1_RICBR
Sequence: MEENLKKTGFLFGGNAVFIEELYKQYLENPASVDQTWQEFFSSVKDSNQLLNKSTAKIILKAAATEESKTSENPVSTTNNFNVGAMIKNYRKYAHYLAKLDPLGLEVTKTKEDLKLSIENFGFTNDQLSKVIEHKFLEKTYNLGELVNFLDKTYAGSIGVEFEQVENEEEKNWLYSKLESGVISFSSEEKKNILNDLVEVEGFEQYLHTKFPGAKRFSVEGGDASIVAMNKAIDLSLHQGVEEIVIGMAHRGRLNTLTKVVGKPYRAVIAGFISGSVFPDELNVSGDVKYHLGYSSDRVVGDKKIHLSLADNPSHLEAVNPIFAGKVRAKQDMLKDNKRSKVKAILVHGDAAFCGQGVVAESLSMSPLAAYNIGGVLHFVINNQLGFTANAADTRASRYSTEFAKIIAVPILHVNGDDIEAVLKATNIAVEYRQKFGKDVIVEIICYRKYGHNEGDEPMYTQGKMYNIIKSKLTPGNIYANELVKSGVIDNNYFAKLKEQFKAKLDKEYEQAKNYKQEAHFLGGLWQGITRTRTQVAVTGVDKKTLQSLGTKLCEMPKDFAVNPKLVKLFDARKAALTADQPIDWATAEQLAFASLLTSGTNIRLTGQDCGRGTFSHRHSVLHNQVDDTTYIPLNNLSKEQATYEVADSNLSEYAVLGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSETKWLRMSGLVVLLPHGFEGQGPEHSSARLERFLQLAAEDNMYVTYPTTPASIFHLLRRQIIDNVRKPLIVMSPKSLLRHKNVVSKLDELGSNTTFLPVLDEVNKLEASNITKVILCSGKVYYDLFEMRGSNSSIAIIRLEQLYPFEKKVVVELLKKYNKASEFIWCQEEPMNMGAWRYITSHLNNALKEAGINNEFKYIGREESASPAVGSLQAHNKQQEKLLKEALGVK
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: RL22_ASTYP
Sequence: METKKPKAIARKVSIAPRKARLVVDLIRGKNIAQAQAILTFTPKVAAPVILKLLNSAVSNAVNNLKLNREQLYVKEVFVNEGLRLKRMFPRAKGSGDMIKKRTSHITLVITSSTNLQTSKEEEQSGSKN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CE12A_MAGO7
Sequence: MKTSAALLFLVSLASAAPMTPSPAAEAAAVLEGRQIQTLCDQYGYWSGNGYYVNNNMWGKDSGSGSQCTYIDSSSANHVSWRSTWQWSGGQNNVKSYPYSGRTIQRGRTIASINSMPSVVQWNYNNGNIRANVAYDLFTSTDPNRDNTHGDYELMVWLGRYGDVQPIGSQIGNANVGGRNWQLWSGLNNGMRVYSFVTTQGAITYFNADIKQFFTYLQQSQGFPASQQYLTTFQFGTEPFTGGQTTFQVNSFGANVQ
What is the function of this protein?
Endoglucanase that functions in part to hydrolyze 1,3-1,4-beta-glucan during infection and spore formation.  Shows preferential hydrolysis of barley beta-glucan and lichenan.
What are the official names of this protein?
Endoglucanase cel12A, Cellulase cel12A, Endo-1,4-beta-glucanase cel12A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 12 (cellulase H) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SUS1_CRYNB
Sequence: MSHVDVTVDEATINAIRQRMLETGDWERIQKLLRAHLEESGWVDDLKDLAKEKARAQDVPNLENLVKQISESAAGMVSDNVKRDVMLEIESVLDREVDQA
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor SUS1.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, P-body.
Protein: DXR_BUCAI
Sequence: MKKITILGSTGSIGINALSIIQKNPDLFKVIALVANKNFSIMLRQCELFSPDWVAMRDEKSAHILRKKLKHSKINTQVLTGEKDICALAALEETDHVISAIVGMAGLLPTLSAIHAGKTILLANKESLITSGYFFMKALSSSGAKIIPIDSEHNAIFQVLPLEIQKNLGKTTLEKNSIKHLVLTGSGGPFYKFSSSDLSNVTPDQACSHPNWLMGKKISVDSATMMNKGLEYAEARWLFNALESEIKILIHPESIIHSMVQYYDGSLLAQLSVPDIRTSISYAMSWPDRICTEVDYLNFYKINNLTFFEPDFTQFPCLKLAIDAFSQGQASMTVLNAANEIAVSSFLDSKISFTKIYEINMEILMSSCFSEPKCIQDILEIDRKVRILAKNKVSSLIF
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: FPG_SACD2
Sequence: MPELPEVETTRRGILPHLEGKRVKAVSVRNRSLRWPIPADLAQQIQNKTLRTIHRRGKYLLLEFANGHVIWHLGMSGSLRIIKADEPPMVHDHVDIAFGGNLALRYTDPRRFGAVLWTNEAILEHKLLNHLGPEPLTDAFNSAYLFDKSRKRSQSVKTWIMDSKVVVGVGNIYANEALFNSAIHPLKAAGKLSQKQCDIFCSEIKSVLAKAIEQGGTTLRDFVGGDGKPGYFAQELNVYGRGGKACKKCRKPLTEKKLGQRTTVYCTHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: ACKMT_CAEEL
Sequence: MGMNTGLVIAGVAGATALAISAAAIPFVAPALRRVCIPYVPATTEQLANVSRALSLATSSNSNKKGTLIDLGSGDGRVVLQCAREGFNSTGVELNSILVAYSKYRSIREGLGKETRFMRKNIFKTDLNPYQTAVIFGAESLMGDLVPKLSEMRSNTNLLACRFPLPENDAWKLEHQIGEGIDAVWVYKRN
What is the function of this protein?
Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C.  Trimethylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration.
What are the official names of this protein?
ATP synthase subunit C lysine N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ANT/ATPSC lysine N-methyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IOLB_BACVZ
Sequence: MSHLLRKPQADEISQGVNIIHDVTSANSDLKYVGFKVVDLTPGSAYTEDLKKTECCIVAVTGKITVTDYDQTFESIGTRESVFERKPTDSVYVSNDRSFEITAVSGARVALCYSPSEHQLPTKLIKAEDNGVEHRGKLANKRTVHNILPDSDPSANSLLVVEVYTDSGNWSSYPPHKHDQDNLPAESFLEETYYHETDPPQGFVFQRVYTDDRSIDETMTAENENVVIVPAGYHPVGVPDGYTSYYLNVMAGPTRKWKFHNDPAHEWILER
What is the function of this protein?
Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
What are the official names of this protein?
5-deoxy-glucuronate isomerase, 5DG isomerase.
What is the protein family that this protein belongs to?
Belongs to the isomerase IolB family.