PharMolix/UniProtQA huggingface dataset:
Protein: ATC9_SCHPO
Sequence: MASPKMIRSKRSTSSIASKNSLNSYLASSLMSHDSIFDGPGLGTSIPSSVSSFHHQTLRPSSDASVSQFSMDYLQSEYNLNRYNDGESIAASRDYQSLLRDNGSGVYSDEEEITEMMLEELNIHPVLRRESVGEAAGLSEDGCCQILYLVEEDLEVGIAGYKTNKSRYRLYQAICLLTLGLAYLIFRWLPKYFIRFVGTREPLATADWLTIETQWGELSKLDIQIQPYENSLSSIFGASIRVAAPEGTENDPFIENFRYVNYRYMKLIFHPLLDRFLIQQDWKDPRWIRDTSVVKEGLERDAINDRLCIFGENLIDLELKSVSQLLIDEVLHPFYIFQVFSIILWSMDSYYYYAICILIISVVSILGSLIETRKTLRRMREMSRFTCPVRVYRDGFWTSISSTDLVIGDVFEISDPELTIFPADALLLSGDCIVNESMLTGESIPVSKIPATDQSMKELFSFSKNIPASLCKHFLFSGTKIIQVRKPFVNEKEEGASLAMVVRTGFNTTKGALVRSMIFPKPTNFSFYRDSFRFITAMFIIALIGFVFSSINLLTLGVPIATIIIRALDLITIVVPPALPATLTIGTTFAISRLRKQGIFCISPQRVNVSGKLDLISFDKTGTLTEDGLDIMGVSVIEGSELGDLRSNSGNLCSKDLLSNDSPSNLLYTMATCHMLRYVDGELVGDPLDIKMFKFTHWSYSEENFLNKKMSSEQAEDAAYVRTQQLIPPTVSPPWNSPSNNYTESDLELGIVRTFEFVSQLRRMAVIVKHGKFKKMDAYVKGAPEIMPSICKPESFPANYQEVLDYYTHNGFRVIACASKQLENCTWAKAQRMKREQVECDLDFCGFIVFENKLKSTTATVIRELNDARIRTVMCTGDNVLTSICVGKRCGMLPEDGYVFLPRFDEESESADEASRQLVWQAIENNEIFLDPHTLRPNVDFADHEPVSIELARLKDFHIALTGDVFRWLVDYAPLNVFHHILLKAQIFARMSPSEKNELVSCFQNLNYCVGFCGDGANDCGALKAADVGISLSEAEASVAAPFTSKWFEITCVLDVIKDGRAALVTSFSCFQYMALYSAIQFITVSILYTTNSNLGDFQFLFIDLVIILPIAVFMGRSRPYHRLAHKRPTANLVSKRILSPLIGQIVLICIIQYITLRIVRREPWYIPPPANSSDTNITNSDVTALFLISCFQYIFIGVVLSIGPPYREKVWRNYSFTAVVVVLLILTVKLIRLQNHKNFFMKLFQLTPTSKSFQNFLIFAGVIYYLLAASGQNYIFISMTNFISHLNNRLLNRRTKVSKKLYKRLFADLQNEQV
What are the official names of this protein?
Probable cation-transporting ATPase C1672.11c.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EFTU_PELUB
Sequence: MSKEKFVRNKPHCNIGTIGHVDHGKTTLTAAITITLAELGGGKAVAYDQIDKAPEEKERGITISTAHVEYETEKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVNAADGPMPQTREHILLGRQVGIPAIVVYLNKVDQVDDKDMIELVEEEIRELLTSYKYPGDKTPIVKGSALAAVEGRDEEIGKNSIIELMKAVDEFIPQPTRDIDKPFLMPVEDVFSISGRGTVATGRIESGVIKTGEEVEIVGVTATKKSVCTGVEMFRKLLDSGEAGDNVGILLRGVERDDIQRGQVLCKPASITPHTKFEAQAYVLKKDEGGRHTPFFTKYRPQFYFRTTDVTGEVTLPAGTEMVMPGDDAKFTVTLITPIAMSEKLNFAIREGGRTVGAGVVTKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_BLOFL
Sequence: MFRVLLINGPNLNLLGIREPEVYGYKNLSDIIISLKKTAVSLNIILNHFQSNAEHELINCIHNSYKNVDFIIINPAALTHTSIVLRDALLAVNINFIEVHLSNIYKREKFRHHSYFSDIATGFICGFGIEGYHFALHMAYKYLTIN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: KDSA_YERPE
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQQFGVKVITDVHEASQAQPVSEVVDVIQLPAFLARQTDLVEAMARTGAVINVKKPQFVSPGQMGNIVEKFKEAGNDQVILCDRGSNFGYDNLVVDMLGINVMVQATGGHPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPEPNSAKCDGPSALPLDKLEPFLVQMKAIDDLVKSFPALDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_DICDI
Sequence: MVLILDNDLKPLYFTLAIISASFLVKRAYQSTNIYDFFNIKKKCNPFPQSQSELVDLLHYQKRMVLNKTIVETLKFVDRKLFLENKNVENPYYDEPKPIGYNATISAPHMHALMLDLLADRIPMSNGVALDIGSGSGYVTACLGHLMGCTGRVIGVEHIPELIERSIESIKRLDSTLLDRIQFLVGDGIKGWKQLKYDIIYLGAAIESLQVARELIDQLKNGGRIVMPVGKSNDFHELMVVDKNEDGIVSIKSLGVVRFVPLTSKENQLNPKNKPNATKVTNINGEKTLIRCEIIPAPDSNSNNNIKEFENLINKK
What is the function of this protein?
Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins.
What are the official names of this protein?
Probable protein-L-isoaspartate O-methyltransferase, PIMT, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: BPT_BORPE
Sequence: MPDMSQLKELPFSTLQFYATAPYPCSYLPGRQARSQVAAPGHLINAGTYSQLVEQGFRRSGLFTYRPHCDNCHACVPVRVDAARFEPNRTQRRAWRSHQALRAFVAELAWSPEHYDLYTRYQQGRHPGGGMDEDSRTQYAQFLLTTRVNTRLVEFRAPQGQLAMISIIDVLDDGLSSVYTFYDPDMAGSLGTYSILWQIEQCRTLDLPWLYLGYWIADSRKMAYKANFRPLQMHVDGAWRETPP
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIDA_SCHPO
Sequence: MTEPLDLAIIGFGPASLSFLIALHDHSEEPLKNKKIRVFEKLPTFSWHEGMLIPGSNMQISFVKDLATPRDPTSYFTFLNYLHSHGQERLSGFLNMSTLEPSRYEYHDYLCWAASHFSKFVEYNANINKLHYDAATDLYIVGHGDTQWQAKNIIITTGCQPYIPPLYKSVDSPLIVHSSKFMSDHSQKLLRNSKHGILVVGCGQSAAEIWKHCHYSLDPKTPLAMCFRNLAPVPSDSSPFVNSLYFDSHNSHWWYNLPTEARLKGLSVGRTTNYSVVKESLLEEMFKECYLQKLRYGQEFHQIMGDTDIQSIKNEGDHLVVQLTSQMDKSKKPETRKIDVLYVATGYDHESFDVLMSSLFPNSQGAQISEEYCVLNAPSKQGKVYVAGITSNQHGIGETLLSWAAIRAGGLAKELFGPSKPTARVPASYLN
What is the function of this protein?
Catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as ferrichrome.
What are the official names of this protein?
L-ornithine N(5)-monooxygenase, OMO, L-ornithine N(5)-oxygenase.
What is the protein family that this protein belongs to?
Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VAPB2_METJA
Sequence: MEIVVDAIYEKGVLKLKKSINLPEGCEVEIKIIPKKISEKTFGILKLSDKEIKEILEEIENGGE
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC2 (Potential).
What are the official names of this protein?
Putative antitoxin MJ0975.
What is the protein family that this protein belongs to?
Belongs to the UPF0165 family.
Protein: DABA_STAA1
Sequence: MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNVDVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTYFSIDQEDYQAYVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAIRLVVEQLLVGDEFKSVTKDCESRSENWFKQTVASLCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQVGTSTKAQIAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETTVFAAAEHHTSTDTLAWVYVPDTLSALALDAYESLNDAMPMISEQANRERLDKLPTIGRVNHPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGKLLNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRTMYHSPIRLLVVIQAPDYVVARLFANNEHFARKVSNHWLRLMSVNEEGRFKSWI
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y743_MYCGI
Sequence: MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALINDPYAKVLVEGAGAGAWRFIADEDLVAKASESDTEVGALFEHMKNYQAVRTHFFDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDYKSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLLMYLPADAQDRLFAQITELSAPGSQVAAESMGVHAPDRRERMRERFASIASQIDIEPMDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRRLDRYVEVADSDGQSFSTFTTGTKL
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mflv_0743.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: RS7_MYCSJ
Sequence: MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLDGKKSLAERIVYGALEQARDKTGTDPVVTLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSVTLALRWLVSFSKARREKTMVERLANEILDASNGLGAAVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: FOLD_LEPBL
Sequence: MDPILLDGKKLSEKIRNEIRREIEERKTKNLRIPKLATILVGNNPASETYVSMKIKACHGVGMGSEMIRLGEQTTTEELLSVIDKLNADPNVDGILLQHPSPSQIDERAAFDRISFRKDVDGVTTLSFGKLSMGVETYLPCTPYGIVLLLKEHGINVSGKNAVVVGRSPILGKPMAMLLTEMNATVTLCHSKTQNLPEIVRLADIVVGAVGKPEFIKADWISKGAVLLDAGYNPGNVGDIEISKAKNHSSFYTPVPGGVGPMTIAVLLLQTLYSSKEHFTPPVQ
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TRPA_GEOTN
Sequence: MRLPVNRSLFIPFIVAGDPSADLTVDLALALQDAGADVLELGVPYSDPLADGPTIQRAAARALAGQMTLPKAIQLVADMRKKGVKIPIIIFTYYNPVLQLGEESFFALAQENGADGVLIPDLPFEESGPLLELSERFGLPLISLVAPTSKQRIEQIASAAQGFLYCVSSLGVTGVRETLPESLGHFLGEVKRHSRVPVVVGFGISTPEQVAMLKDACDGVVVGSALVQKIEQLLERLQTLEEKNAAIAEFASYARSLAAPLREPCSSR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: FABZ_LACPL
Sequence: MSVLEASEIMQLIPNRYPILFMDRVDELNPGESIVVTKNVTINESFFQGHFPGNPVMPGVLIIEALAQAASILILKSEKFAGKTAYLGAIKDAKFRKIVRPGDVLKLHVQMVKQRSNMGTVSCQAMVGDKAACTTDLTFIVGATDSK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_SYNJA
Sequence: MNWLETALSTSSLKEAPAVAVLHLGCEKNRVDTEHMLGLLAQAGYRVEGDEDSADYVIVNTCSFIEAARRESVSTLMELAVQGKKIIIAGCLAQHFQEELLREIPEAVAIVGTGDYHQIVQVIQRAERGERVNAVTSSLDYIADETVPRYRTTHAPVAYLRVAEGCDYRCSFCIIPHLRGKQRSRPIESILREAEQLAAEGVQELILISQITTNYGLDLYGEPRLAELIRALGQIPIPWIRMLYAYPTGITPAVVEAIQETPNFLLYLDLPLQHSHPAILKAMNRPWQGQVNDRLIERLRQALPKAVLRTSFIVGFPGETEEHFQHLLEFVQRHQFDHVGVFTFSPEEGTPAYHLPQQVPEPLKEERRARLMQLQQGIAFRRNREQVGQVVPVLLEQENPRTGEWIGRSPRFAPEVDGVVYVRGPGSLGSLVPVQITRAEPYDLFGQVVEAPAGFSWSGR
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_PROMT
Sequence: MDSSTLIKRLETAKSSFQNLELQLADPDVASDPKQLETIARERSRLEPLVNDYLKLQIIEKECLEAKGLVKESRDDKEMELLAREELQNLELSKNELIQKLTLALLPKDPRDERSVMLEIRAGAGGNEACLWAGDLARMYERYGQKLGWNVKPISSTEADMGGFREMIISVKGESVYSQLKFEAGVHRVQRVPSTESQGRVHTSTATVAVMPEADPVEVKIESTDLEISTARSGGAGGQNVNKVETAIDLFHKPSGIRVFCTQERSQMQNRERAMEILRAKLLELELAEANAKERSARLSQVGTGDRSEKIRTYNYKDNRTTDHRLGVNFPLEQVLSGQLEDVIGACIAEEQKRQMEELSNQSED
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTGL_PSEF5
Sequence: MISNAPMHLWQGRIDLAEGLAARRWHQWVQPWAEQQPAGIALLGLACDEGVKRNQGRTGASQGPAALRAALANLAWHGTGPLYDAGDVTCTDHHLESAQKRYAERLGLLLEQGHLVLGLGGGHEIAFASFSGLADHLRRQQPCPRIGILNFDAHFDLRHAPQSSSGTPFRQIAEYCRQAGMPFEYCCLGVSELSNTQALFEQARELDVRYLLDRQMQGWNLPAVEACLDAFLDGIDVLYMTLCLDVLPASQAPGVSAPSAHGVDVQVVEHLVRRARASGKLRVADIAELNPGLDQDQRTARVAARLLASLIH
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: KPRS_VIBVU
Sequence: MPDMKLFAGNATPELAQRIADRLYISLGDATVSRFSDGEVAVQINENVRGSDVFIIQSTCAPTNDNLMELVVMIDAMRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSNVGVDRVLTIDLHAEQIQGFFDVPVDNIFGTPVLLEDMHARGLEDPVVVSPDLGGVVRARATAKALGDIDIAIVDKRRPRANVSEVMNLIGDVEGRDCVIVDDMIDTGGTLCKAAEALKERGAKRVFAYATHAVFSGNAAKNIKNSVLDQVIVTDSITLSKEMAATGKVTQLTLSGMLAEAIRRISNEESISAMFN
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_LYSSC
Sequence: MNNFSHWNEAGRPKMVDISEKEITTRTAIARSTITLSNEVYQAIQQGGIKKGDPTQVAQIAGIMGAKKTADIIPMCHPIMLQGTDLQFDYEKIDNGYALHIQATVKCNGKTGVEMEALTAVSIAALTFYDMCKAVDKTMVIKETYLVEKTGGKSGTFTHK
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: YCIB_EDWI9
Sequence: MKQLLDFLPLVVFFVCYKLYDIYVASGALVAATAVALVLTWLKYRRVEKMTLITFIMVAIFGTLTLVFHNDLFIKWKVTVIYTLFALALLISQVVLKKPLIQRMLGKELQLPDSVWSRLNAAWALFFLGCGLANIYVAFWLPQSVWVDFKVFGLTALTLVFTLLSGIYIYRNMSEEQKHS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPX_METEP
Sequence: MSKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGVPTPKEIRRVLDDYVIGQDFAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLERIISQRGKGTSIGFGASVQAPDDRRTGEVFRSVEPEDLLKFGLIPEFVGRLPVLATLEDLDEEALKKILQEPKNALVKQYQRLFEMENVELTFQDEALSLVARKAIERKTGARGLRSILETILLDTMYDLPGLESVEQVVIGPEVVEGKSRPLFIHGDRNKEAPASVSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: DCC1_DANRE
Sequence: MRTLEEVQGTLQIAKVKEEDLQPVTYCLSFGDNVSSGDYCLMEVDENLCKHIESGKSLIIRGDKDEHAVLCSEDKTYDLKIADTSNLLLFVPGCKTPDQLSDIPASPQLMHTQIWGFSNCYWELRRQRPRLKKLKKLLMENPYDGPPVGMQEEAPGLKYSMEDLLERIQASKEELEAHLGNVHACEIDGFWRILDFDYEMKLLGHVTQLVDSESWSFSKVPLSVCLEELGSLEPKAMIEHCLNCYGRRHSDEDNQVMYALDEDKVCRATAQLLLQNAVKFNLSEFQEVWQQSVPEGMGTRLDQLRGLALIDRSSKPETISLLRVEDLPEDTLERFNSLFSLREKWTQDDIEPYIQDLCGEKQTTGALLTKHARSSMQNGIKVYNSRRPVAT
What is the function of this protein?
Loads pcna onto primed templates regulating velocity, spacing and restart activity of replication forks.  May couple DNA replication to sister chromatid cohesion (By similarity).
What are the official names of this protein?
Sister chromatid cohesion protein DCC1, Defective in sister chromatid cohesion protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the DCC1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VPS33_SCHPO
Sequence: MTTDVKEKATFKLLDLIDSVTGKKSLLLERDLSGILGQIVTTNTLQEHGIPQVYWFNENIPNDIEKKTIYLCRPTYENAKLVATHVRQFQRDMLRIESTVIVLPTSNILFETVLQEEGVFGELLVTEWPLHAVPLDKDLLSLELGPEKLEESLLQRSTDALIDFERTHGRFPRVSGRGPYAAKMLELLEKTYQEEATINFGKVEGEISALYDSVLLVDRSLDRITPFLTQLTYFGFLDEILGIQQMNVKLPSSLVNRNEASNTGPMKKFSLSSSSSQITKEIRDINFNCIGPYLSKIARKLSSDFEGRRQAKTVNQIRDFVSKLGSLQSEHTSLNIHTGLAETLVQHTKNNYFQKLLQLQHLLVSHADSFTQFNLLDEIIYAEAPVEEVFRVLCLASITTNGLRRKDIDHYRREITQTYGYYHLLTFQALIDAGLLRLRQSTNISLQKSLSYSTWLNTYPLVKDEVDEQNPEDIAYTYSGYGPLSVHIAYDILKGRDNEEKILKLQNMPGTYVDKWTLDQEKVMPKNLKTNVPGKRRVLVFFIGGCTYTELAAFRLLQEKEDLYEFTFMTTGMVTGSSLIRAFIPNIESLNE
What is the function of this protein?
Essential for vacuolar biogenesis, maturation and function.  Involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 33.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
Protein: VWA1_BOVIN
Sequence: MLPWTVIGLALSLRLARSGAERGLPASALQGDLLFLLDSSASVSHYEFNRVREFLGRLAALLPVGPGALRASLVHVGSRPHTEFPFGQHSSGSAVQDAIRAAAQRMGDTNTGLALAYAKKQLFAKAAGARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNLLELSAAASAPAEKHLHFVDVDDLHIITQALRGSILDAMWPQQLHASEVTSSGFRLAWPSLLTADSGYYVLELAPSTDPGAARRQQLPGNATGWAWTGLDSDTDYDVALVPESNVRLLRSQHLRVRTLPEETGPELIVVSHTRPRSLRVSWAPALGPDAALGYHVQVGPLRGGAAQSVEVPAGENSTTLQGLAPGTAYLVTVTAAFRSGRERALSAKACTPEGERSRAPRPQPQRTGGREP
What is the function of this protein?
Promotes matrix assembly (By similarity).  Involved in the organization of skeletal muscles and in the formation of neuromuscular junctions (By similarity).
What are the official names of this protein?
von Willebrand factor A domain-containing protein 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: NSP4_ROTH2
Sequence: MEKLTDLNYTLSVITLMNSTLHTILEDPGMAYFPYIASVLTVLFTLHRASIPTMKIALKTSKCSYKVVKYCIVTIFNTLLKLAGYKEQITTKDEIEKQMDRVVKEMRRQFEMIDKLTTREIEQVELLKRIYDKLMVRATDGIDMTKEINQKNVKTLEEWKSGKNPYEPKEVTAAM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: MENC_ENTFA
Sequence: MNIQSIETYQVRLPLKTPFVTSYGRLEEKAFDLFVITDEQGNQGFGELVAFEQPDYVQETLVTERFIIQQHLIPLLLTEAIEQPQEVSTIFEEVKGHWMGKAALETAIWDLYAKRQQKSLTEFFGPTRRKIPVGISLGIQEDLPQLLKQVQLAVEKGYQRVKLKIRPGYDVEPVALIRQHFPNLPLMVDANSAYTLADLPQLQRLDHYQLAMIEQPFAADDFLDHAQLQRELKTRICLDENIRSLKDCQVALALGSCRSINLKIPRVGGIHEALKIAAFCQENDLLVWLGGMFESGVGRALNLQFASQPTFSFPGDISATERYFYEDIITEPFILEQGTMTVPQGLGIGVTLSQTNLLKYSQYQKIM
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24872444).  Also acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of N-succinyl-L-phenylglycine (PubMed:24872444).  Since the gene is encoded in a menaquinone synthesis operon, OSB synthase is probably the physiological activity.  A pathway that requires NSAR activity has not been identified in this species, so whether NSAR is also a biological activity is unknown (PubMed:24872444).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, N-succinylamino acid racemase, NSAR, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
Protein: G1091_SHESA
Sequence: MHNIHRRHFLKAAGAVTAGLVTANIALNANASSVAPKPRVGKSVIGLIAPKMELVRVGFIGVGERGFSHVEQFCHLEGVELKAICDTHQAVIDRAVEHIVKQNRPKPAVYTGNDLSYRELLNRDDIDIVIISTPWEWHAPMAIDTMESGKHAFVEVPLALTVEECWQLVDTAERTQKNCMMMENVNYGREELMVLNMVRQGVFGELLHGEAAYIHELRWQMKEIDHKTGSWRTYWHTKRNGNLYPTHGLGPISQYMNINRGDRFDYLTSMSSPALGRALYAKREFPADHERNQLKYINGDMSTSLIKTVKGRTIMVQHDTTTPRPYSRHNLIQGTNGVFAGFPNRIAVEHGGFGKSYHEWDMDMQKWYDKYDHPLWQRIGKEAEINGGHGGMDFVMLWRMVYCLRNGEALDQDVYDGAAWSVVNILSEQSLNNRSNSVNFPDFTRGAWEHATPLGIVGA
What is the function of this protein?
Glycosidase.
What are the official names of this protein?
Glycosyl hydrolase family 109 protein 1.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
Protein: YG27_YEAST
Sequence: MIYAQPLCYPRLSRLTHSYEALERRRRTFHCRNTCLFKNTLTVGTTISIKLICGLHYATQHTGSFTRHLLHCTSFAFAKLNVARCNYYTVHPSSPFLNFTFSLDFTHRTYKVTFINIEINYR
What are the official names of this protein?
Putative uncharacterized protein YGR064W.