PharMolix/UniProtQA huggingface dataset:
Protein: COPZ1_BOVIN
Sequence: MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMTVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLLR
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).
What are the official names of this protein?
Coatomer subunit zeta-1, Zeta-1-coat protein, Zeta-1 COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: HSLV_SHISS
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOSSC_TAEGU
Sequence: MAANPSGQGFQNKNRVAILAELDKEKRKLLMQNQSSTNHPGASIALTRSPLNKDFRDHAEQQHIAAQQKAALQHAHAHSSGYFITQDSAFGNLILPVLPRLEAE
What is the function of this protein?
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint.  The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability.  Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) (By similarity).
What are the official names of this protein?
SOSS complex subunit C, INTS3- and NABP-interacting protein, Sensor of single-strand DNA complex subunit C, Sensor of ssDNA subunit C, SOSS-C, Single-stranded DNA-binding protein-interacting protein 1, SSB-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the SOSS-C family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to nuclear foci following DNA damage.
Protein: RPOB_CAUSK
Sequence: MAQSFTGKKRIRKSFGRIPEAVQMPNLIEVQRSSYEQFLQREVRPGVRKDEGIEAVFKSVFPIKDFNERAVLEYVSYEFEEPKYDVEECIQRDMTFAAPLKVKLRLIVFETEEETGARSVKDIKEQDVYMGDIPLMTDKGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHASGKLLFAARVIPYRGSWLDFEFDAKDVVYVRIDRRRKLPATTFLYALGMDGEEILTTFYDVVPFEKRTAAGAEGWATPYKPERWRGVKPEFALIDADSGEEVAAAGTKITARQAKKLADNGLKTLLLAPEALTGRYLARDAVNFETGEIYAEAGDELDVTSIEALAAQGFSTIDVLDIDHVTVGAYMRNTLRVDKNAVREDALFDIYRVMRPGEPPTVEAAEAMFKSLFFDAERYDLSAVGRVKMNMRLELDASDEMRVLRKEDVLAVLKLLVGLRDGRGEIDDIDNLGNRRVRSVGELLENQYRVGLLRMERAIKERMSSVDIDTVMPHDLINAKPAAASVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATHARVNKYGFIESPYRRVADGKPLEEVVYMSAMEESKHVIAQSNIKVLNGEIVDDLVPGRINGEPTLLQKEQVDLMDVSPRQVVSVAAALIPFLENDDANRALMGSNMQRQAVPLVQSDAPLVGTGMEAVVARDSGAVVIAKRTGVVEQIDGTRIVVRATEETDAARSGVDIYRLSKFQRSNQSTCINQRPLVKVGDKISAGDIIADGPSTELGELALGRNALVAFMPWNGYNFEDSILISERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVGEEALRNLDEAGIVAIGAEVQPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVAGTIVDVRVFNRHGVDKDERALAIERAEIDRLGKDRDDEFAILNRNISGRLRELLIGNVALSGPKGLSRGQITAEGLAEVQPGLWWQIALEDEKAMGELESLRRLFDENRKRLDRRFEDKVDKLQRGDELPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVISRILPIEDMPFLADGTHVDVVLNPLGVPSRMNVGQIFETHLGWACAGLGKQITTLLEDWQAGGQKQALIDRLTEIYGPDEELPETEEELVELARNLGKGVPIATPVFDGARIGDIEDHLRMAGLDPSGQSILYDGQTGEQFKRPVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ORN_MYCA1
Sequence: MRDELVWIDCEMTGLDLGSDKLIEIAALVTDAELNVLGDGVDVVIHADDAALAAMGEVVTEMHSRSGLIDEVKASTVDLATAEEMVLDYIRTHVKAPKTAPLAGNSIATDRAFIVRDMPALDSYLHYRMIDVSSIKELCRRWYPRIYFGQPVKGLTHRALADIHESIRELQFYRRTAFVAPPGPSTSEIEAVAAALDEGKDAPGPSDSASAPPTG
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_BACC0
Sequence: MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQNAKEKFSSYGEQFITVKSNFRYLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQDAPLTAYDVVNSWSYEQLVRIFFQYGEEKFSKQIARKIEAYRENKAIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVITFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRARSAKLRIAEKR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAQ_BACSU
Sequence: MLRHSPQFSVYRIALTLFFMMLSLLYLFPIFCLLLGSLKPSSELLRVGLNLDIDPKVMSFDNYTFLFNGGSIYFKWFFNSLVLGLFTTVLTLFFSSMIGYGLAVYDFKGRNIIFVLVLIIMMVPLEVMMLPLFKLTVGLHLIDSYTGVILPFIVSPVAVFFFRQYALGLPRDLLDSARMDGCTEFGIFFRIMAPLMKPAFGAMIILQSLNSWNNFLWPLIVLRSKEMFTLPIGLSSLLSPYGNNYDMLISGSVFAILPVIIIFLFFQKYFISGLTVGGVKG
What is the function of this protein?
Part of the ABC transporter complex AraNPQ involved in the uptake of arabinooligosaccharides.  Transports alpha-1,5-arabinooligosaccharides, at least up to four L-arabinosyl units (PubMed:20693325).  Responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Arabinooligosaccharides transport system permease protein AraQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PACA_BPP7
Sequence: MTWDDHKKNFARLARDGGYTIAQYAAEFNLNPNTARRYLRAFKEDTRTADSRKPNKPVRKPLKSMIIDHSNDQHAGDHIAAEIAEKQRVNAVVSAAVENAKRQNKRINDRSDDHDVINRAHRTLRDRLERDTLDDDGERFEFEAGDYLIDNVEARKAARAMLRRSGADVLETTLLEKSLSHLLMLENARDTCIRLVQEMRDQQKDDDEGTPPEYRIASMLNSCSAQISSLINTIYSIRNNYRKESREAEKHALSMGQAGIVKLAYERKRENNWSVLEAAEFIEAHGGKVPPLMLEQIKADLRAPKTNTDDEENQTASGAPSLEDLDKIARERAASRRADAALWIEHRREEIADIVDTGGYGDVDAEGISNEAWLEQDLDEDEEEDEEVTRKLYGDDD
What is the function of this protein?
Necessary for recognition and cleavage of the phage packaging site (pac), together with the pacB protein.  Both are probably the two major subunits of the phage PACase (By similarity).
What are the official names of this protein?
Terminase A protein, DNA-packaging protein A, PACase A protein.
Protein: RECN_HELPY
Sequence: MRDFNNAQITRLKVRQNAVFEKLDLEFKDGLSAISGASGVGKSVLIASLLGAFGLKESNASNIEVELIAPFLDTEEYGIFREDEHEPLVISVIKKEKTRYFLNQTSLSKNTLKALLKGLIKRLSNDRFSQNELNDILMLSLLDGYIQNENKAFSPLLGALEEKFTRLEKLEKERRLLEDKKRFQKDLEERLNFEKMKLERLDLKEDEYERLLEQKKLLSSKEKLNDKIALALEVLENTHKITHALESVGHSAEFLKSALLEASALLEKEQAKLEECERLDIEKVLERLGMLSGIIKDYGSIMHAKERLGHVKNELHNLKEIDSHCETYHKEIERLKTECLKLCEEISGFRKEYLAGFNALLSAKAKDLLLKSPSLVLEDAPMSEKGAQKLVLNLQNSQLETLSSGEYSRLRLAFMLLEMEFLKDFKGVLVLDEMDSNLSGEESLAVSKALETLSSHSQIFAISHQVHIPALAKNHILVFKENHKSLAKTLNNEERVLEIARMIGGSENIESAISFAKEKLKAQE
What is the function of this protein?
May be involved in recombinational repair of damaged DNA.
What are the official names of this protein?
DNA repair protein RecN, Recombination protein N.
What is the protein family that this protein belongs to?
Belongs to the RecN family.
Protein: FAAH1_PIG
Sequence: MVQEELWAAFSGPSGVALACCLVAAALALRWSSRRMARGAAARARQRQQAALETMDKAAQRFRLQNPDLDSEMLLALPLPQLVQKVRSGELSPEAVLFSYLQKAWEVNRGTNCVTTYLADCEAQLCQAPGQGLLYGVPVSLKECFSCKGHDSTLGLSRNQGTPAECDCVVVQVLKLQGAVPFVHTNVPQSMFSYDCSNPLFGQTTNPWMSSKSPGGSSGGEGALIAAGGSPLGLGTDIGGSIRFPSAFCGICGIKPTGNRISKSGLKGSVYGQVAVQLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFNEEVYASSRPLRVGYYETDNYTMPTPAMRRALLETKRSLEAAGHTLIPFLPANIPHALEALSTGGLFSDGGKRLLQNFEGDYVDSCLGDLISILRLPKWLKGLLAFMLRPLLPRLAGFLSSLRPRSAGKLWELQHEIEMYRHSVIAQWRALDLDVVLTPMLSPALDLNAPGKATGAVSYTLLYNCLDFPAGVVPVTTVTAEDEAQMEHYKGYFGDIWDKVVQKAMKRSVGLPVAVQCVALPWQEELCLRFMREVERLMAPGRQPS
What is the function of this protein?
Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules (PubMed:10526230, PubMed:12664593).  Also catalyzes the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol) (PubMed:10526230, PubMed:12664593).  FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids (By similarity).
What are the official names of this protein?
Fatty-acid amide hydrolase 1, Anandamide amidase, Anandamide amidohydrolase 1, Fatty acid ester hydrolase, Oleamide hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Note=Seems to be associated with the endoplasmic reticulum and/or Golgi apparatus.
Protein: SYY_YERPA
Sequence: MTSSNLIKQLQERGLVAQVTDEDALAERLAQGPISLYCGFDPTADSLHLGHLVPLLCLKRFQLAGHRPVALVGGATGMIGDPSFKASERKLNTEDTVNEWVEKIRHQVSPFLDFDCGENSAIAANNYDWFGGMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDSGISFTEFSYNLLQAYDFACLNKNHGVALQIGGSDQWGNITSGIDLTRRLHQQQVYGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSLEEINALEEEDKNSGKAPRAQYVLAENVTGMVHGPEGLAAAKRITDSLFSGDLHDMTEADFAQLAQDGMPTVELNRDADLQQALVNAELVPSRGQARTMIGSNAVAINGEKQADPEYVFTDADRLFGRYTLLRRGKKHYCLISWL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_CHLCV
Sequence: MKEDPYLEVKRHLAREAAALVTSGMLLGLGSGSTSREFIKAVAERKKQENLDIRAVASSKESYSLASSLGIPLIDDEEFINTDLAVDGADEIDPQLRMIKGGGGAIFREKILLQSSQRRLILADESKSVKVLGKFGLPVEISPFGRSSIIATLENFGYLGNLRKNPRGGFFITNNGNYIYDIHTPNVYPHPEEDLLKLLQIHGIIEAGFVIENVEVWLGYTNGQIGKKNTGGL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MURC_CLOBB
Sequence: MSFDFIKDRDKKVHFIGIGGISMSGLAAVLLNSGYKVSGSDFKESEILKKLRLSGADIYIGHSEKNIKDVDLVVYTAAIPENNPELIYAKENNIELMNRAEFLGSIMKGHKYNVAISGAHGKTTCTSMLSNITLKANLDPTILVGGELDIIGGNFRIGSSDYFITEACEYKRSFLSFFPYVGVILNIDADHLDYYKDIDEITETFGQFADLIPNDGYLIGYVGDSRVKEILFKAKCNTLSYGFENADVTARNITFNEKGCASFDVYKHNDKLFDLTLSNPGEHNILNALSSICVSLIFDVNYDDIICGLSECKGAHKRFEYKGEVNGVTVIDDYAHHPVEIKATLNTSKKIPHNKTFCVFQPHTYTRTKTLFDEFTDAFFDADEVVLMDIYAAREKDTGLVSSNDLGVALRAKGVKCTNVHSHDEALEYLKNSAKPNDLLLTVGAGDVVIVGEKYLNQGK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_ORYSJ
Sequence: MARGLKKHLKRLNAPKHWMLDKLGGAFAPKPSSGPHKSRECLPLILIIRNRLKYALTYREVISILMQRHVLVDGKVRTDKTYPAGFMDVISIPKTGENYRLLYDTKGRFRLQSVKDEDAKFKLCKVRSVQFGQKGIPYLNTYDGRTIRYPDPIIKANDTIKIDLETNKIVDFIKFDVGNVVMVTGGRNTGRVGVIKNREKHKGSFETIHVEDALGHQFATRLGNVFTIGKGNKPWVSLPKGKGIKLSIIEEQRKRDAAAQAAANA
What are the official names of this protein?
40S ribosomal protein S4, SCAR protein SS620.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_LEGPC
Sequence: MKLLFDFFPIVLFFIVYKFFGIYTATAVAMVASLTQVAFYRLKFQHYEKMHLFSLAIIMVLGGATLFFQNPWFIKWKPTGIYWLSALVFYGSGYIGSKPLIQKMMEANINLTTKIWYRLNLAWTLFFIVMGALNLYVAYHYDTDVWVNFKLFGGVGFTLLFVLIQAFYLTKHTDEKSFEKQ
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL10_PELUB
Sequence: MNKEQKKNYISEMETQFQNNEAVMVTHYQGLTMSQLDELRAQMREHGIKFTITKNRITKIALEKTKCKELSNLFTGATAVAFSNDAIISARILSKFAKTNESLKLLGGIMGNEVLDQAAVQNVANLPTLDEARANLVGILATPASKLVSILLARSEKMSSLSPENS
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: VHED_BPR32
Sequence: MFKRKSTAELAAQMAKLAGNKGGFSSEDKGEWKLKLDNAGNGQAVIRFL
What is the function of this protein?
Binds preferentially to single-stranded DNA and therefore, destabilizes double-stranded DNA.  It is involved in DNA replication, repair and recombination.  Binds ss-DNA as the replication fork advances and stimulates the replisome processivity and accuracy.
What are the official names of this protein?
Single-stranded DNA-binding protein, Gp32, Helix-destabilizing protein.
Protein: XERS_STRPG
Sequence: MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKNDLEAFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQKLFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIISLLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMKL_SHEAM
Sequence: MFNFFAAAPKGFEYALAKELETLGAENVRESVAGVYFSASLAQGYQITLWTRLASRIVLILFTGECQSAEQLYNAAYTIDWPSHFSNRSTFSIDFHGTGGFINNSQFGALKIKDAVVDRFRDDDLSRPDVVKGHPDMRIDAHYGRGKITIGINFSGAALHQRGYRGNTGEAPLKENLAANMLYRSGWADNPVTLLDPFCGSGTVLIEAALMACDIAPGLMRERFGFEHWRRHDQALWQQVIEEAKARASLGKTRCQLKFYGSDIDSRVVALAKRNANSAGVFDFIDFKVANALNLEPPVAEGMVLTNPPYGERLGNVTSLLQLYFQLGEKFKQSYGGWKLGLLCSDMELVSSLKLKADKQMKMYNGALECAFNLYTLHATSTRRDIPVDTTGQGGEIAAPFANRLKKNLKQLEKWAKREGIDSYRLYDADIPEYNVAVDRYLDYVVVQEYAAPSAIPEAVTKRRLTDVLLALPRALGIDPDKIVLKTRERQKGTNQYQKLDGEKLELVTTEYGCSFKLNLTDYLDTGLFLDHRLTRKLVGEKAKNRDVLNLFAYTGSASVHAGKGGAKSVTTVDMSNTYLNWAKDNFMLNGLIGRQYQFEQADCLQWIRDCERQFDLIFIDPPTFSNSKRMEDSFDVQRDHVDLLASLKKLLRPGGEIVFSNNKRKFKMDMEALAAAGLKAVNIDDKVLPMDYARNPQIHNCWVVTHG
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHAM_SALSV
Sequence: MFESKINPLWQSFILAVQEEVKPALGCTEPISLALAAAAAAAELDGTVERIDAWVSPNLMKNGMGVTVPGTGMVGLPIAAALGALGGNAKAGLEVLKDASAKAVADAKAMLAAGHVAVMLQEPCNDILFSRAKVYRGDSWACVTIVGDHTNIVRIETDKGVVFTQADNAQEEEKTSPLGVLSHTSLEEILAFVNAVPFDAIRFILDAARLNGALSQEGLRGSWGLHIGSTLAKQCDRGLLAKDLSTAILIRTSAASDARMGGATLPAMSNSGSGNQGITATVPVMVVAEHVGADDERLARALMLSHLSAIYIHHQLPRLSALCAATTAAMGAAAGMAWLIDGRYDTIAMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHNVEQSISNLCSLACRSMQQTDKQIIEIMASKAH
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: LEU3_AGRFC
Sequence: MTVRSLFLLPGDGIGPEAMTEVRKLIEYMNSAHNAGFTVSEGLVGGSAYDAHGVAISDADMEKALAADAILFGAVGGPKWDGVPYEHRPEAGLLRLRKDLELFANLRPAICYPALAAASSLKPELVEGLDILIVRELTGGVYFGEPKQIIDLGNGQKRGIDTQIYDTFEIERIASVAFELARSRDNRVCSMEKRNVMKSGVLWNQVVTETHAAKYKDVQLEHMLADAGGMQLVRKPKQFDVIVTDNLFGDMLSDVAAMLTGSLGMLPSASLGAPDAKTGKRKAMYEPVHGSAPDIAGKSIANPIAMIASFAMCLRYSFNMVDEATKLEAAIANVLDKGIRTADIMADGCRQVGTSDMGDAVLAEFKALSA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPB_RHIEC
Sequence: MTPKLILASSSPFRRMLMENAGLFFEAHPAEIDERAVEAPLEKAGAKPDTVACVLAKAKAEDVSARFPESLVIGSDQTMSLGDRVFHKPKDIADAANHLRALSGTTHRLNSAIVLVRDGAVLWEHVGHAELTMRPLTEDFIARHLSRVGERALSSVGAYQLEGEGVQLFEKIEGDYFTILGLPMLPLLGKLRELGTIDG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKA_STAA8
Sequence: MKFKRLATIFSAVLVLSGCGSMHSSGKDLNISLPLKTKSIAPYETDVPVKIGAAESLFKTNDQGKIEKALVKSYHQPNDTTLDIELKDNIKFQNGQKLTAEKVKSSLENSMKKSDLVKYSLPISSITAKGQKLTIKTNSAYPELVSELANPFMAIYDTDAKSDVNQTPVGTGPYQIKDYKQSRKISLSNFKDYWQGKPKLDHITVTYQEDGNNRVRNLESQKDDLITDVPVNKVQDIENNQNLKVSKESGFRTSLLMYNHTNKKMTKSVREALDHIIDRQGIADHIYQGYAKPATSPFNDKIPYIKEPKLTKQNIEQAKMLLAKDGYTKEHPLKIKLITYDGRPELSKIAQVLQSDAKKANIEIDIKSVDDIEGYLKDRSAWDATMYSFGTIPRGDTGYFFNQAYKKDGAINKGDYNNSNVDDLINQLNHTVDVKERHNISNDIIKLSSRDVPNSYIAYNDQIVAANSKVKNYKVTPEGIYLIDYRTTIER
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Binds nickel and transfers it to the membrane-bound permease.  Required for full urease activity and plays a significant role in the virulence of S. aureus during urinary tract infection (UTI) (PubMed:20662775).  May bind nickel via a nickel-chelator (PubMed:25611161).
What are the official names of this protein?
Nickel-binding protein NikA, SaNikA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CH60_CYACA
Sequence: MSKRILYKDQARKALERGIDVLAKAVSITLGPKGRNVVIDKKYGAPQIINDGIAIAKEIELKNHMENTGVSLIRQAAAKTNDVAGDGTTTATVLAHAIIKQGLKYVSTGSNPISLKKGIEKASQFIIQKISENSRPIEDVKSIIQVSSISAGNDEEIGSMIANAIQKVGKDGVISLEEGKSAITELEITQGMKFEKGYISPYFITNSEKMEVVLENPYILMTDKKITLVKEDLLPVLTLINKTNRPLLIIAEDVEKEALATLVINKLRGIVNVVAVRAPGFGDRKKALLEDIAILTNGQVISEETGLNLETITLDVLGQARRATILRDSTTIVEDKNQQAVHARCEQLKNQLLIAKSSYEKEKLQERLAKLIGGVAVIKVGAATETEMKEKKLRLEDSINATKAAIEEGIVPGGGTALVHISANLKQWAKINLSSDELLGANIVEQASLAPLHKIAENSGKNGSLIVEALEHKNFEIGYDALSNSLVDMYDAGIIDPAKVTRSAIQNAASIASMVLTTECVIVNRDKKNN
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, chloroplastic, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSBE_GOSHI
Sequence: MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDSLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.