PharMolix/UniProtQA huggingface dataset:
Protein: LUXS_YERPG
Sequence: MPLLDSFTVDHTIMKAPAVRVAKTMKTPHGDEITVFDLRFCVPNKEVMPEKGIHTLEHLFAGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVTDQRKIPELNEYQCGTYHMHSLEEAQSIAKDILDRDVRINHNEELALPKEKLTELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RL39_SULTO
Sequence: MSKNKPLGRKLRLARALKSNSPVPAWVIIKTNGKFRYNFHRRDWRRNDLKV
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: FABZ_CLOBH
Sequence: MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDVLKLSIDLTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNTF_PIG
Sequence: MAFAEHSPLTPHRRDLCSRSIWLARKIRSDLTALMEAYVKHQGLNENINLDSVDGVPMASTDRWSELTEAERLQENLRAYRTFHVMLARLLEDQREHFTPAEDDFHQAIHTIVLQVAAFAYQLEELMVLLEHKVPPSEADGTPLSVGGGGLFEKKLWGLKVLQELSQWTVRSIRDLRVISSHQAGVPAHGSHHVAKDKKM
What is the function of this protein?
CNTF is a survival factor for various neuronal cell types.  Seems to prevent the degeneration of motor axons after axotomy (By similarity).
What are the official names of this protein?
Ciliary neurotrophic factor, CNTF.
What is the protein family that this protein belongs to?
Belongs to the CNTF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_ECOL6
Sequence: MAPPLSPGSRALIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AIM24_TALMQ
Sequence: MRLTLGKGATVVYRARAGACATRRHGVRNLRIKAAPLGELTVVNGVNLPISSTPSSASSADAKFHVVGTPYSMLSVSLSASQNLYTRRGTLVGLSGKADNVISTLSVLEPLRRAVFGIPFLYQKISSPSPIKALVSVQSPVTSFAVVHLDGTVDWMIVQRRALLAWTGHSLNIKPRINRHLSVTNWGSSEVTGRGLLALVGRGQVYSIELKAGEQYIAHPSNVVAYTLASMPPQPYRFKSTTLRFQIPGLDIPELLLKSRYIRDFTASDTWKASMRIFHNVRTWARRTIWGDRLFLRFEGPATLLVQSRGARVRDIMSDREVNEIADTPAGTTFNAINKLTGVTKEDKSDYQRAAEEAVSQAPVPSRTVEGLTQELKGVSQAIAIIRDGRVEFETFKSQNDDARK
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRPD_CHLCH
Sequence: MESKQLLQKLLAGEHCSKEEMQDCMNSIMDGEFSDSVIAALLALLQKKGVVANELAGAHASLMAHATTVALSTHAVDTCGTGGDHGGTYNISTTASLIACSAGVRVAKHGNRSVTSSCGSADVLEALGFTLELPPEATISLFKKTGFAFLFAPLYHPSMKRVAHIRRELGIRTLFNMLGPLLNPAQVKRQLVGVFSEELSELYADVLLQTGARHALIVHASTEEGVILDEPSLNGTTFVTEIEKGVVRKHTLRPEEFGIAPAPLAALQGGDKEHNARIIQSIADGSASAAQRDAALYSSAMACYVGGKCACLNDGFIVAKEALESGKTQAKLKEIIAYNQALVTEYHVAKS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CX7A1_SAISC
Sequence: MLAPRVSQALIRSFSSTARNRLKNRVPEKQKLFQEDNGIPVYLKGGVVDHILYRVTMGLCLGGTAYGVYCLAWASFPRNK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7A1, mitochondrial, Cytochrome c oxidase subunit VIIa-heart, Cytochrome c oxidase subunit VIIa-H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIa family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PURA_GLUDA
Sequence: MSNVTVIGAQWGDEGKGKIVDWLASRADIVVRFQGGHNAGHTLVVGSQTYKLSLLPSGLVRGKMGVIGNGVVVDPEALLAEIDRVSAQGLEVSPRTLRIAENVPLILPVHGAIDRAREAARGDRKIGTTGRGIGPAYEDKVARRAIRLCDLAEPETLDWKLDELLLHHNTLLAGLGAETFTKDALLAHLTALAPRVLPYMDTVWDLLDDARRAGRRILFEGAQAVMLDVDHGTYPFVTSSNTIAANAATGSGVGPGSVGFVLGIAKAYSTRVGEGPFPSELHDDMGRTLGERGHEFGTVTGRPRRCGWFDAMLVRRAVRVGGVNGLALTKLDVLDGLPEIRVCVGYELDGQEIRSFPSSPAAQARVKPIYETMEGWTDTTYGARSWADLPAQAIKYVRRIEELVEAPVTLLSTSPERDDTILMRDPFEN
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_AERPE
Sequence: MRRAYTVKQLLESYRAGDTDPVEHVSRVLDALRRWERDVNAFISLEAEEVLIDAAEEAARRWRRGEARRLEGVVVGVKDNISTSFLPTTAGSRMLDGYIPPFNATVVERLLMEGAIIIGKTNLDEFAMGSTGEFSAFGPTRNPWDLSRVPGGSSSGSGACLAYGACDAALGSDTGGSVRLPAAYTATVGLKPTYGLVSRYGLIPYANSLEQISPMARSSEDVMLLLEVIAGGDEYDATSIYSKPTTASREEGLKPEDLSLCIPEELVEHSEEAVRKAFYNTVGKLEGLGARLEYVGLGGAEAYALPAYYTIALAEAASNLARYDGSLYPVRGSSGDYWRQAAEARGIGFGLEVKRRILMGVYVLSEGYKDEYYLAATKLRRVIRDAMLKTVGKCLVATPASPIMPPRIGERVDDPLKLYAMDVYTVLANLSGLPAIALPIEIHGGLPVGLQLIGPRLGERLLAGAANIIEDLTGLAGVVAG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RRF_BORBZ
Sequence: MEDYKAFLDEKMSKVLLSLDNEYKTLRTGRISSNIFDKIFIQYHGQRTPITQVSSIRIPEARLVVIQPWDKTILNKIEQAILNSDLSMNPSSDGSVIRIKVPALTSERRQDIVKHAKKIAEEHKISTRNIRQDLNNKVKKQEKESEITEDSLKRILDDIQKSTDIYIKKIDAILESKIQEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_CHLCH
Sequence: MANPLLCPLLTEKSTGLTEKKGQYVLVVRPDADKLTIKDAIEKKFGVSVTSVRTINYLGKLRAQNTRRGRIIGKKSDWKKAIVTLAEGQSIDYYSGTAQKSEG
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CAPSD_NODAM
Sequence: MVSKAARRRRAAPRQQQRQQSNRASNQPRRRRARRTRRQQRMAATNNMLKMSAPGLDFLKCAFASPDFSTDPGKGIPDKFQGLVLPKKHCLTQSITFTPGKQTMLLVAPIPGIACLKAEANVGASFSGVPLASVEFPGFDQLFGTSATDTAANVTAFRYASMAAGVYPTSNLMQFAGSIQVYKIPLKQVLNSYSQTVATVPPTNLAQNTIAIDGLEALDALPNNNYSGSFIEGCYSQSVCNEPEFEFHPIMEGYASVPPANVTNAQASMFTNLTFSGARYTGLGDMDAIAILVTTPTGAVNTAVLKVWACVEYRPNPNSTLYEFARESPANDEYALAAYRKIARDIPIAVACKDNATFWERVRSILKSGLNFASTIPGPVGVAATGIKGIIETIGSLWV
What is the function of this protein?
Membrane-permeabilizing peptide produced by virus maturation, thereby creating the infectious virion.  After endocytosis into the host cell, peptide gamma is probably exposed in endosomes, where it permeabilizes the endosomal membrane, facilitating translocation of viral capsid or RNA into the cytoplasm (By similarity).
What are the official names of this protein?
Capsid protein alpha.
What is the protein family that this protein belongs to?
Belongs to the peptidase A6 family.
What are the subcellular locations of this protein?
[Capsid protein beta]: Virion. SUBCELLULAR LOCATION: [Peptide gamma]: Virion. Note=located inside the capsid.
Protein: YAFD_ECODH
Sequence: MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERIRILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFVLPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNFSLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTDDQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK
What are the official names of this protein?
UPF0294 protein YafD.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_SHEON
Sequence: MEDLQLVLFVLGAIAIVAVLVHGFWSIRRQQPKSLKDSPMGNFYKKQAERGEAAPAPKRVDAEGFDSDGIGAVRVRKASESQTPEAPAVNPYLKQEAKVEPQIEPKPQFKQEPSMAQPDFSLQSPSVDEPHRGTKASRQEPVLKSNTAHLNQEHAGQSHAAMVAQKVAEEQRAQVQKPTQTALFDDEVYQEQQPQAVEEAPETEESLGEPRDVLVLHVVAKEGQQLNGAELLPCFLTLNFKYGDMNIFHRHVDNAGNGKVLFSIANMVKPGVFDPDNMEQFSTLGVVFFMTLPCYGDALMNFSIMLNSARQLADDIDAVVLDGQRQPWGEFTKQDYLHRIRANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: WDR46_MOUSE
Sequence: METAPKPGRGVPPKRDKPQAKRKKPRRYWEEETTPAAVATSPGPPRKKARTGESRPPRSKSAHIAQKSRFSKKPPISKTAPDWKKPQRTLSGAQDPFPGPVPAPLEEARKFCRIDKSKTLPHSKPKTQSKLEKAEAQEEEASVRAARAELLLAEEPGFLVGEDGEDTAKILQTDIVEAVDIASAAKHFDLNLRQFGPYRLNYSRTGRHLALGGRRGHVAALDWVTKKLMCEINVMEAVRDIHFLHSEALLAVAQNRWLYIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATTSETGFLTYLDVSVGKIVTALNVRAGRLSVMAQNPYNAVIHLGHSNGTVSLWSPAVKEPLAKILCHRGGVRAVAVDSTGTYMATSGLDHQLKIFDLRGTFQPLSSRTLPQGAGHLAFSQRGLLVAGMGDVVNIWAGQGKASPPSLEQPYLTHRLSGHVHGLQFCPFEDVLGVGHSGGFTSMLVPGAAEPNFDGLENNPYRSRKQRQEWEVKALLEKVPAELICLNPRALAEVDVVTLEQQKKERIERLGYDPDAKAAFQPKAKQKGRSSTASLVKRKKKVMDQEHRDKVRQSLEQQQQKKKQDMAMPPGARPSALDRFVRRAREGGLQVDP
What is the function of this protein?
Scaffold component of the nucleolar structure.  Required for localization of DDX21 and NCL to the granular compartment of the nucleolus.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
WD repeat-containing protein 46, WD repeat-containing protein BING4.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RECG_BORBU
Sequence: MFLHEFEYELKGIGGLGEKGVERLNNLQIFNVKDLIEFFPVKYEDRQNIQTFPDFSKVKSCDMMTVFTVLGHKKFGDSSKKNLKLTVKSINEEPFEILLFNRAFLENVFKIDKKFYIYSKFTYNDYSGLWSCSNFDSEVYSDKPERFKKILPVYSLTEGLTSKKISLYVKEALEYFFKFGQTDIPRFLIEKYSLLSLSDALKEIHFPSSLEMLEKAKKTLIYREIFLLQFFSRYRSSKILFREKKDLSKDLLEKVVSSLPFELTEDQKISIDEIFFDLNSSKPMNRLLQGDVGSGKTLVALLSGLPLIEAGYQVAFMAPTDLLARQHYDNLSNILAPFNISMTLLTGSLRKKDKEQALESIRNGTSGLIVGTHAIFYESTEFKRLAYVIIDEQHKFGVVQREELKNKGEGVDMLLMSATPIPRSFALTLFGDLEVSFIKTLPKGRLPITTYLARHGNEDKVYEFLRKELLKGHQVYFVYPLISSSEKFELKDVNNMCLKLKEVFGEYVVDMLHSKLPSDLKEEIMKNFYSKKVDILVATSVIEVGIDCPNATCMVVEHAERFGLSTLHQIRGRVGRSNLQSFFFLLYKEPLTSAGKFRLKTIKENLDGFKIAEEDLRLRGPGNLFGLEQAGYLKLKIANFVDDREIIVLVREELDLFFYDNSAYDKLDIDLLDNLFCSYLNAGRSI
What is the function of this protein?
Critical role in recombination and DNA repair.  Helps process Holliday junction intermediates to mature products by catalyzing branch migration.  Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity.  Unwinds branched duplex DNA (Y-DNA) (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase RecG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.
Protein: FABZ_CHLAD
Sequence: MLSIQEIMALIPHRYPFLLVDRIVELEPGVRAVGEKLVSANEPYFQGHFPGNPIMPGVLILEALAQTGAVAALSLPEHAGKLVLFAGIDGARFKRVVRPGDTLRLEVQLERMRRGIGKGQARATVADQLACEAELLFAVTDPTK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_ROSCS
Sequence: MVNDVLREAESRMKKATEALRNHLATIRTGRASPALVEHLHVEAYGATLPLNQLATITVPEPRMLVIQPFDANTVKAISKAIMNSELGITPTDDGRLIRLAIPQLTEARRKELTKLVRARVEESKVALRNIRREALEDLRDLEHEKMISEDEHRRAQEKLQELTDRYVRELDHIGATKEAEVMEI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM24_DEBHA
Sequence: MKANIAMASKQLQFIRSLIISQPPTIALPNQSSNISKIENIKGNDLPNQKTLNDPEFQSLGQPASVLAINSPPSVPIYIRKNSLLSIYGIDNSFVNSIKGSVEFINPLKRFIYGGYVSKYQKIISTVPFSLLVSSSSKNFRLRTNRQKSFATLLLDGTNDWAVLNNTALQAYTGGTLNVSMFRIPKNISKTLASLLKITNATETGLFRWNNLGYALLTGRGQVGLVGNGAIYNINLKENEEVLISRKNLLSISVNGPYDLQNCIVKYSFPVTKPETGTIGSTKEAPVQLNKDDVIPANNFNHYWNIIKGYSRHIINFFKRSQRLTYNFLVGNEDFVRVIGPRNLLLQSNSVGSHSTSSSELPKPNLSNIKANIEKKSSDFLNYVTIEPGRGAVFKSTPNFRESVQKIEKKSS
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CS4F1_MYXXD
Sequence: MSVVVTRYRGGGPQYMNASSTSPKPVVGEPSIRTHALHALAYCERLFYLEEVEELRVADAAVFAGRRLHVQLQEEGEHVELELASEALGLHGRVDAVKTREGTLVVYEHKRGRHAPGGDAPEAWPSDRLQAGAYALLVEERFPGAPVECRVRYHQTDTTVRFPLDAALRGAVVAAVARARLLRASRERPPVTQEERKCAKCSLAPVCLPEEERQVVGEERPRLFPEDDVRQVLHVATPGTRVGRAAEELVVTPPEGEGAPSRQPGRMVSALIAHGAVQVSAQALAYCVENDIGVHWFTSGGRYLGGLGGGAGNVHRRLRQFEALRQASVCLGLARRLVAAKLEGQLRFLLRASRGDSESRQVLASAVRDLRALLPKCEEAPSLEVLLGLEGAGAARYFGALPYLQGEDVDTRLRFEGRNRRPPRDRFNAVLGFLFGLVHREVEAAIRAVGLDVAFGFYHQPRGTAGPLGLDVMELFRVPLADMPLVASVNRRAWDADADFEVTSEHVWLSKAGRAKAIELYERRKRETWKNNVLGYSLSYARLVELEVRLLEKEWTGKPGLFATFRLR
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).  The Cas4 region acts as a ssDNA exonuclease, while the Cas1 region acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
What are the official names of this protein?
CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: UREE_YERPS
Sequence: MILIEHILGNVKKDPVWREKLKDATFDLLILDQREAQKSRCRKSSTQGLDLGISLDRNVVLADGDVLAWDEETNVAVVVQINLRDVMVIDLSELKSRSPDELIKTCFELGHALGNQHWKAVTKHNEVYVPLTVATTMMDSVMRTHGFQHLPFRFVKGAEILPLLTNSEARLLFGGAEDTDTHVHVASPLDEPHGSGLHIHGIHSHGEGHSHGDHDHDHSHSHGDHDHDHKH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPA1_ORYSJ
Sequence: MLTKFETKSNRVKGLSFHPRRPWILASLHSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFTLHGHLDYIRTVQFHHEYPWIVSASDDQTIRIWNWQSRTCVAVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDILRLTQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAWEVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRIWDATKRTGIQTFRREHDRFWILSAHPEMNLLAAGHDSGMIVFKLERERPAFSVSGDTVFYVKDRFLRFFEFTTQKEVQLAPIRRPGSVSLNQSPKTLSYSPTENAVLICSDVDGGSYELYIVPKDSAGRADYLQDAKKGAGGSAVFVARNRFAVLEKSSNQVLVKNLKNEIVKKSPLPIATDAIYYAGTGNLLCKAEDRVTIFDLQQRLILGELQAPSVKYVVWSSDMESVALLSKHAVVIANKKLVHRCTLHETIRVKSGAWDENGVFIYTTLNHIKYCLPNGDSGIIKTLDVPIYITRVIGNNIFCLDRDGKNKLVTVDASEYIFKLALLRKRYDHVMSMIKNSQLCGQAVISYLQQKGFPEVALHFVKDEKTRFNLALESGNIQIAVASAKEIDDKDHWYRLGIEALRQGNVGIVEYAYQRTKNFERLAFLYLITGYMDKVGFMCKIAGQNNNLMGQFHNALYLGDALKRVEILENAGQLPLAYITATTHGLTEIADRLAAELGENIPSLPEGKARSLLIPPAPLTASGDWPLLRVMHGIFEGGLDATGKAELEEDDEAAGADWGDEDLDMVDASEAMANGGDGFDAEEGEANEEDGEEGGWDLEDLELPPEAETPKNAGNARSAVFVAPPPGMPVSLIWTQKSSLAGEHAAAGNFDTAMRLLSRQLGIKNFAPLKPLFVDLHMGSHSYLRALATAPIIPIAVEKGWSESASPNVRGPPALVFTFPQMEDRLKAAYKATTDGKFPEALRQFLSILHTIPLIVVDSRREVDEVKELIEIVREYVLGLRMELKRKELRDDVNRQQELAAYFTNCKLQRVHMRLVLGSAMGLCYKQKNFATAEHFARMLLENNPNEAQARRARQVQQQCSGKKDSSELNYDYRNPFVVCGATYVPIYRGQKDVSCPYCGSRFVPSIEGQLCTICELAVVGADASGLLCSPTQSR
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit alpha-1, Alpha-coat protein 1, Alpha-COP 1.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: RL13_LISMO
Sequence: MRTTYMAKPGEVERKWYVIDATGVSLGRLSSEVASILRGKNKPQFTPHIDTGDFVIIINAGKIGLTGKKATDKIYYRHSQYPGGLKSRTAGEMRTNNPEKLLELSIKGMLPKNSLGRQLFKKLHVYGGSEHEHAAQQPEVYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: DNLJ_SYNWW
Sequence: MEVSSRIKELREEMQKHDYHYYILDAPLISDSGYDRLMQELKKLEEEYPQYITADSPTQRVAGKASEKFSPVRHRFPLLSLDNAFSYQDLLEFDRRIGRVARTLSYMAELKIDGVSIALVYENGVLLNAATRGDGLVGEDVTANIRTIKTIPLRLRHSLPRLEVRGEVFMPKQEFIRLNEEKEEKGERVFANPRNAAAGSLRQLDPRVTAGRALSAFVYDIIYMEGQTLAEQQEAWHFMQELGLPVNPEVRFCADINAVLAFTEEYAEKRHELPYEIDGVVVKLNTLAEREELGATARSPRWAMAYKFPAEEKETRLLGVEINVGRTGIIAPTALLEPVFLAGTTVSRASMHNFDLIKEKDLRIGDMVLLHKAGDIIPEIIASLPEKRSGEERVITPPENCPACDSKVARFAGEVAYRCENINCPARLKESLIFFASRGAMDIDGLGSAVIEQLVNKDMVKRIDDLYRLREEEITALERMGPKSAANLIKAINESKSRPLSRLLTALGIRHIGARSAKILSRHIHDIDDFYKLGVENLTSIPEIGPKMAESMVNFFAEPRNRETIEDLKDLGVNTREEAIEAGEQLLQGKTFVLTGTLPSLTRQQASEMIESRGGKVSSSVSKKTSYVVAGDDPGSKLDKALQLELTILDEAGFLNLLGLS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MDH_RHOBA
Sequence: MRRAKITIVGAGNVGATCAHWCAAAELGDVVLLDIPRTEDMPRGKALDLMQASPIMGFDSNIVGTTDYADTADSDVIVVTAGLPRKPGMSRDDLLATNAKIVTSVAEEIKATSPNAVIIVVSNPLDAMVQQMFKVTGFEPAKVIGQAGVLDTARYRTFLAMELGVSVEDISALLMGGHGDTMVPVPSCTSVGGIPVTQLISKERLDEIVDRTRKGGAEIVSLLKTGSAYYAPAAACAQMVEAIVKDKKRVIPVAAYCDSEYGVGGYYVGVPVVLGSGGVERIIELSLTDEETKAFQNSVDAVKSLVSTMDGLLAE
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: Y833_DESVH
Sequence: MVDARHATGQHGEDEAAALLQRTGHRIIARNWRHGGLELDIICETGDTIVFVEVKTRAAHGLTSPTDALTHQKRHRLIRAARAWLAAADAWDRACRFDLVCVTQRGATCTLEHITDAFDLTETLGGGDTSWQPW
What are the official names of this protein?
UPF0102 protein DVU_0833.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.