PharMolix/UniProtQA huggingface dataset:
Protein: RLMN_BRASB
Sequence: MARTAGLREPAAPLEKTPLETYVPPAKPSLIGLSRAELAARLGDVGVPERQQKMRVQQLWHWIYFRGARSFDEMSSVSKDTRTALAERFTVDRPEVVAEQISNDGTRKWLLRLPSGDDLQKAHEVECVYIPETDRGTLCVSSQVGCTLNCAFCHTGTQRLVRNLTAGEIVGQVMVARDRLNDWADRETPHGNRLITNIVMMGMGEPLYNFDAVRDALLIVSDNEGIGISRRRITLSTSGVVPNIKRAGEEIGVMLAISLHAVRDELRDELVPLNRKYPIAELLQACRDYPGASNARRITFEYVMLKGVNDSLDDARLLVKLLKGIPAKINLIPFNPWPGSAYECSDWEQIEKFSEYVFNAGYSSPVRTPRGRDILAACGQLKSETEKLSARERQALRAMAMTD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI_NITWN
Sequence: MSGLGFTGVVRIAVMALLALAFLGAPAHATSRIKDLANIEGVRQNQLIGYGLVVGLNGTGDTLNNIPFTKQSLQAMLERMGVNIRGATIRTGNVAAVMVTGNLPAFATQGTRMDVTVSAMGDARSLQGGTLLVTPLLGADGNVYAVAQGSLAIGGFSAEGAAASVTKGVPTNGRIANGAIVEREIEFALNRMPNVRLALRNGDFTTAKRIAAAVNDFLGTKTAEPIDPSTVQLSIPAEFRGNVVALLTEIEQLQVEPDITAKIIIDERSGIIVMGRDVRVATVAVAQGNLTVSISESPQVSQPNPLSNGRTVMTPRTDVGVTENGNKLALVKNGVSLQELVDGLNGLGIGPRDLIGILQAIKAAGAIEADIEVM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: CLPP_SHEB8
Sequence: MHNASDIQSALVPMVIEQTAKGERSYDIYSRLLKERIIFLVGQVEEHMANLIVAQLLFLESESPDKDIFLYINSPGGSVTAGMAIYDTMQFIKPNVSTVCIGQAASMGAFLLAGGEKGKRHCLPNSRVMIHQPLGGFQGQASDIAIHAKEILGIKNKLNQMLAEHTGQPLEVVERDTDRDNFMSATQAVEYGLVDSVMTKRG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLTP2_ACTDE
Sequence: TVSCGQVDTALTPCLTYLTKGGTPSTQCCSGVRSLKSMTGTKVPDRQAACNCLKQAAARYQGIKDAAAALSQKCGVQLSVPISRSTDCSKIS
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).
What are the official names of this protein?
Non-specific lipid-transfer protein 2, LTP2.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: MRAY_ENTFA
Sequence: MEWTQIFIPIVVSFAITVSVMPLFIGYFQMKKQGQVTREDGPTWHSVKTGTPTMGGVVFLVASLITSLAMGLFFHQFTPSLLIILFILVLYGLLGYLDDFIKVFKKRNMGLNSRQKLIGQIFGGLVFYFVYRSEGFSDTLDLFGVAEVPLGIFYGVFIIFWLVGFSNAVNLTDGIDGLVAGLGTISFGTYAIIAWKQQQFDVVIICLSVIGGLIGFFPYNRKPAKIFMGDVGSLALGGLLAAISIILHQEWTLLLIGLVYVCETASVILQVASFKLFGRRIFKMSPIHHHFEMCGWSEWKIDFVFWSVGLICSGITLWILF
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPT_ECO81
Sequence: MKRISTTITTTITITTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: Y525_PSEAE
Sequence: MAFAVELEEWVGAHWHRFITRHASGEFEAARVTLESMRRPLGMLFRALGGAPGVALEATPARRLLLRRTWLQRVAGTCEQAPVSWFNGDSLRLPESLAVYPQAELNRELYRWLALLAASAGPLRHWAQDNQRWARQLLDAYPALRPRYARLVAAHLRQRPSLDDCPAADAELEIALRRALAEPGSVERFPRVERAPWPVPLWLYPGERWTPSASAEDGEEAAAGAGKRQVARSGARKRAERIEERNSERNLLLFRLESLLSWSEHLALDRCSDDEDDPDGARVAEDLDYLSLSRQRTQKGGGLRLDLDLPAADYDDLPLGPGLKLPEWDYRQQRLLSDHVLLQPMRPRGATSASLPAHLEKTALHLRRQFACLRDGRQRLRQQPQGDEIDLDAWLDFQVERRRGGSTQPGLFLEQRPRRRDLACLLLADLSMSTEAYLDDQRRVIDSIVDSLLLFGEALQALGDPFALYGFSSVRRQQVRWQVLKDFDEGYGGEVRGRVLALSPGYYTRMGAAIRRASQVLGGQPQKRRLLLLLSDGKPNDLDRYEGRYGIEDTRQAVIEARSQGLVPFCITIDKEAADYLPYLFGADGFALVERAGQLPERLLQLYRRLRR
What is the function of this protein?
Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification).  Function unknown, but essential for the denitrification process.
What are the official names of this protein?
Uncharacterized protein PA0525.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIZ2_ORYSJ
Sequence: MALDPADDPLLADCKYKLNHFRIKELKDVLHQLGLPKQGRKQELVDKIIAVLSDQQEQDSRLNGLPNKKMVGKETVAKIVDDTFAKMNGSTNAVPASRNQTDSGHIVKPKRKSDDSAQLDVKVRCPCGYSMANDSMIKCEGPQCNTQQHVGCVIISEKPADSVPPELPPHFYCDMCRITRADPFWVTVNHPVLPVSITPCKVASDGSYAVQYFEKTFPLSRANWEMLQKDEYDLQVWCILFNDSVPFRMQWPLHSDIQINGIPIRVVNRQPTQQLGVNGRDDGPVLTAYVREGSNKIVLSRSDSRTFCLGVRIAKRRSVEQVLSLVPKEQDGENFDNALARVRRCVGGGTEADNADSDSDIEVVADSVSVNLRCPMTGSRIKIAGRFKPCVHMGCFDLEAFVELNQRSRKWQCPICLKNYSLDNIIIDPYFNRITALVQSCGDDVSEIDVKPDGSWRVKGGAELKGLAQWHLPDGTLCMPTDTRSKPNIRIVKQEIKEEPLSEETGGRLKLGIRRNNNGQWEINKRLDSNNGQNGYIEDENCVVSASNTDDENSKNGIYNPEPGQFDQLTSNIYDLDSSPMDAHFPPAPTEQDVIVLSDSDDDNVMVLSPGDVNFSSAHDNGNAFPPNPPEASGICGEQPRGAGPDVTSFLDGFDDLELPFWESSSSQDAAGTQVTDNQCEMQNFIVNHQFLHEPILGVNLGGTAASNTLECEHDGALQACQSSDQDGDQNQTCHDGHSGDLTNLSIISTQDSLTNGKNASQKRTNCEDGTAGLDGSVVRSANGLRGEMPPLGQEQDRTVRQKLILTIESDSD
What is the function of this protein?
Probable SUMO E3 ligase that may regulate Pi starvation responses.
What are the official names of this protein?
E3 SUMO-protein ligase SIZ2, E3 SUMO-protein transferase SIZ2.
What is the protein family that this protein belongs to?
Belongs to the PIAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEF_PSET1
Sequence: MATLEVLRFPDERLRTIAQEVAHVDDQVRVIIKDMLETMYDENGIGLAATQVNIHQRIVVIDVSEERNEPLVLINPQIIKKDGTTVSEEGCLSVPNSYAKVDRAETVTVAALNEQGEEFVLDADELLAICIQHELDHLQGKLFIDYLSPLKRQRIRKKLEKEAKFAE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: D2HDH_HUMAN
Sequence: MLPRRPLAWPAWLLRGAPGAAGSWGRPVGPLARRGCCSAPGTPEVPLTRERYPVRRLPFSTVSKQDLAAFERIVPGGVVTDPEALQAPNVDWLRTLRGCSKVLLRPRTSEEVSHILRHCHERNLAVNPQGGNTGMVGGSVPVFDEIILSTARMNRVLSFHSVSGILVCQAGCVLEELSRYVEERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGTLGIITTVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAVCMQLVGRHLHLASPVQESPFYVLIETSGSNAGHDAEKLGHFLEHALGSGLVTDGTMATDQRKVKMLWALRERITEALSRDGYVYKYDLSLPVERLYDIVTDLRARLGPHAKHVVGYGHLGDGNLHLNVTAEAFSPSLLAALEPHVYEWTAGQQGSVSAEHGVGFRKRDVLGYSKPPGALQLMQQLKALLDPKGILNPYKTLPSQA
What is the function of this protein?
Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate (PubMed:15070399, PubMed:15609246, PubMed:16037974, PubMed:20020533, PubMed:33431826).  Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC) (PubMed:33431826).  Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC (PubMed:33431826).
What are the official names of this protein?
D-2-hydroxyglutarate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS9_MESHJ
Sequence: MNQPELSYYGTGRRKSSVARVTLKHGNGQFKINNRVAKEYLKSDILIKDALQPLSITNTVSEFNIRVNAHGGGISGQAGAIRLGIARALLKVSADYRPGLKVAGMLTRDARAKERKKFGLRKARRARQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: PHR_SYNP6
Sequence: MAAPILFWHRRDLRLSDNIGLAAARAQSAQLIGLFCLDPQILQSADMAPARVAYLQGCLQELQQRYQQAGSRLLLLQGDPQHLIPQLAQQLQAEAVYWNQDIEPYGRDRDGQVAAALKTAGIRAVQLWDQLLHSPDQILSGSGNPYSVYGPFWKNWQAQPKPTPVATPTELVDLSPEQLTAIAPLLLSELPTLKQLGFDWDGGFPVEPGETAAIARLQEFCDRAIADYDPQRNFPAEAGTSGLSPALKFGAIGIRQAWRAASAAHALSRSDEARNSIRVWQQELAWREFYQHALYHFPSLADGPYRSLWQQFPWENREALFTAWTQAQTGYPIVDAAMRQLTETGWMHNRCWMIVASFLTKDLIIDWRRGEQFFMQHLVDGDLAANNGGWQWSASSGMDPKPLRIFNPASQAKKFDATATYIKRWLPELRHVHPKDLISGEITPIGRRGYPAPIVNHNLRQKQFKALYNQLKAAIAEPEAEPDS
What is the function of this protein?
Involved in repair of UV radiation-induced DNA damage.  Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
What are the official names of this protein?
Deoxyribodipyrimidine photo-lyase, DNA photolyase, Photoreactivating enzyme.
What is the protein family that this protein belongs to?
Belongs to the DNA photolyase class-1 family.
Protein: AUR44_RANAE
Sequence: GLLQTIKEKLKELATGLVIGVQS
What is the function of this protein?
Has no antimicrobial or anticancer activity.
What are the official names of this protein?
Aurein-4.4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Aurein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GCST_BURCJ
Sequence: MTALNHTPLNAAHRALNARMVDFGGWDMPVNYGSQIEEHAAVRTDAGMFDVSHMCVVDFTGSRVRAFFEHAIANNVGKLKTPGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTADKDIAWFNQLNEQGGYGLTIAPRRDFAIVAVQGPNAREKVWATVPSARAATSELKPFNAAQVAGTPFGDLTIARTGYTGEDGFEVIVPAVHVEVLWNALQQHGVRPCGLGARDTLRLEAGMNLYGQDMDDTVSPLDAGLAWTVDLAAPRDFVGRAALEANGTRAAFVGLILQKENGKAGGVLRAHQKVVTPHGEGEITSGTFSPSMQESIAFARVPAAVQIGDTVQVQIRDKNLPARVVKLPFVRNGKVLAA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RAB4A_DANRE
Sequence: MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDDSNHTIGVEFGSKIISVVNKFVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAESIQECGC
What is the function of this protein?
Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (By similarity).  Involved in protein transport.  Plays a role in vesicular traffic.  Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (By similarity).
What are the official names of this protein?
Ras-related protein Rab-4A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm. Early endosome membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Note=Generally associated with membranes. Cytoplasmic when phosphorylated by CDK1.
Protein: SYL_HAEIG
Sequence: MQEQYRPDMIEPKVQQYWVENKVFKAIKDESKEKYYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPFGWDAFGLPAEGAAIKNKTAPAKWTYENIAYMKKQLQLLGFGFDWDREIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLGGLDTLPQWPDMVKTMQRNWIGRSEGVEITFDVANTNEKVAVYTTRPDTFYGVSYLGIAAAHPLASLAAQNNPELAAFIQEAKNAKVAEADLATMEKKGMATGLFAIHPLTGEKLPIWVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYSLPIKQVIAPLADEEIDLTKQAFVEHGKLVNSAEFDGKDFDGAFNGIADKLEKLGVGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVPAPMEDLPIILPEDVVMDGVKSPIKADPNWAKTTLNGTPALKETDTFDTFMESSWYYARYTCPQYQNGMLDAEEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSEEPADKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLERDEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYQYQQNPAKTSLDITALSAEQKVLRREVHKTIAKVSDDIGRRQTFNTAIAAVMELMNKLTKAPLDSEQDRAVMAEALSAVVRMLYPITPHICFELWQALGNESAIDTAEWVKADEAAMVEDEKLIVVQVNGKVRGKVTVAADADEDTVKTIAFADENVKKFIDNQHIVKVIYVVGKLLNVVVKP
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_XANOR
Sequence: MNFHEYQSKQLLAEYGIPVPSGKVAATPDEAVDVATSLGKGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTKMSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHGRDFGFKLGLNAKQAGQFASIMVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDETEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MIAA_BORPE
Sequence: MTPRAIICLAGPTAAGKSASTLALAQRWPLEIINVDSATIYRGMDIGTAKPSAAERAQVPQHLLDIRDPAQSYSAAEFRADALRLIAEIHARGRIPLLAGGTMLYYKALREGLDDLPQADPALRAELEARAARLGWPALHAELALLDPATAARLSPNDSQRIQRALEICRLAGQPMSALLQGERRGDAPSPYRYVTLSLEPSERAALHARIAQRFDAMLAAGLVEEVRGLHARPDLHPGLPSVRCVGYRQMWSYLDGDIDLDTAREQGVAATRQLAKRQLTWLRAQPERVIIDCLAGDAVARTVDAMARALPD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MB12B_HUMAN
Sequence: MRSCFCVRRSRDPPPPQPPPPPPQRGTDQSTMPEVKDLSEALPETSMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDIKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNSTRTDYEYQHSNLYAISAMDGVPFMISEKFSCVPESMQPFDLLGITIKSLAEIEKEYEYSFRTEQSAAARLPPSPTRCQQIPQS
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.  Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
What are the official names of this protein?
Multivesicular body subunit 12B, ESCRT-I complex subunit MVB12B, Protein FAM125B.
What is the protein family that this protein belongs to?
Belongs to the MVB12 family.
What are the subcellular locations of this protein?
Endosome. Late endosome membrane; Peripheral membrane protein.
Protein: RECA_SALDC
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPVYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGDNVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYNGEKIGQGKANATTWLKENPATAKEIEKRVRELLLSNQNATPDFAVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UGT2_PUEML
Sequence: MKDTIVLYPNIGRGHLVSMVELGKLILTHHPSLSITILILTPSTTPSTTTFACDSNAQYIATVTATIPAITFHHVPLATLPSNTPSLPPHLVSLELARHSTQNVAVAFQTLAKASNLKAIIIDLLNFNDPKTLTQNLNKNIHTYFYYTSGASTLALLLHYPTIHETLTKNYVKDQPLQIQIPGLRANITTDDFAKDSKDPSNYSSQAFLKIAETMRGSFGIIINTFEAIEEELIRALSEDGTVPPLFCIGPVISAPYGEDDKGCLSWLDSQPSQSVVLLCFGSMGSFSRTQLKEIAVGLEKSEQRFLWVVRAELDCADSVDEQPSLDELMPGGFLERTKEKGLVVRDWAPQVQILSHDSVGGFVTHCGWNSVLEAVCEGVPMAAWPLYAEQRVNRVIMVEDMKVALAVNEDKAGFVSATELGDRVRELMESDKGKEIRQRTFKMKISAAEAMAEGGTSRVALDKLAKLWKES
What is the function of this protein?
Glycosyltransferase that possesses isoflavonoids 4'-O- and 7-O-glucosyltransferase activities (PubMed:27066037).  Shows a successive glucosylation toward the acceptors producing their corresponding 4',7-O-diglucosides (PubMed:27066037).  Can use genistein, formononetin, daidzein, liquiritigenin and naringenin as substrates (PubMed:27066037).  Shows also a 3'-O-glucosylation activity in vitro (PubMed:27066037).
What are the official names of this protein?
UDP-glycosyltransferase 2, PlUGT2, UDP-glucose:isoflavone 4' 7-O-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: MED18_ASPFU
Sequence: MHELLLFASVPAHQHHELLQQLAGLTAMQPQHRLERRLVFKAYRKPGLVNVRVGASQDLQGAELQRLNKMLNGGMFYTQVVGPVSEADFGAPASPVADQDAHMSGTDEKSSVRPHYYDYENQPWKLEFRDIPEAATRSAVTTRLMASASLPKGDVTVPMNAWGYNFVTEYAVEGDIFIHNDIVIFLHRVLHYPTESQEPRRQLPALNEMTPLDRSGGYVLQAAITVQDGSNQETMKIASQHLFGLREQLKSAVRLEQADRLSLDTRAK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NAGZ_PECAS
Sequence: MGPVMLDVASYELDAEDREVLEHPLVGGVILFTRNFHDVAQLRELVRQIRAASHERLVVSVDQEGGRVQRFRDGFTRLPAAQAFAALNSVSEAQRLAEEGGWLMAAEMIAMDIDISFAPVLDIGHQSAAIGERSFHEQPEMALAVAQSFIRGMHSAGMKVTGKHFPGHGAVSADSHKETPRDPRPLAEIRAHDMLIFKALIQSQQLDAIMPAHVIYTEADPHPASGSSYWLKTVLREELGFDGIIFSDDLSMEGAAVMGSYPERAQAALQAGCDMILVCNHREGAISVLDNLSPVKAEQLTRLYHQGSFSRRELLDSPRWKLANQALTSLSERWQAHKNGEK
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STP1_HUMAN
Sequence: MSTSRKLKSHGMRRSKSRSPHKGVKRGGSKRKYRKGNLKSRKRGDDANRNYRSHL
What is the function of this protein?
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals.  In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
What are the official names of this protein?
Spermatid nuclear transition protein 1, STP-1, TP-1.
What is the protein family that this protein belongs to?
Belongs to the nuclear transition protein 1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids.
Protein: POLG_VESVA
Sequence: MAQTLSKISNKENASSGLRPKRFKPHQPIPTWMVRCEPLDHDSRRGRDPVRASPQAKRVRTPTPYPRHLKPAASAVVRSGNNPSHLKPASTDVVRSGPQPLCCEAKDGGVVRSCKTYNLKPAHESKAVAFSLPKTDGPTGNEPEFIAEACPSCALYDTCPNCTSKVINDDGSTDGTIPSWDQIETTPAFLSLLSNTDEEMSADELTNLAAHLRKAFETGSHPANVDYSKDQLQGLLEMAEAAVPPARRQTLPFYQQRLEARRTWREKIFNQPLEEINKILTTSKDRFQRCAAWKVILEKAVLAKEYGEEAYAYAQQALKNINSFDVNLVLKMAAATFIDHIRMMTVDNPDLVSYIPKLIVKLKPLTLKMIIDNHENTKEGWLVTLTSLAELYGMVEVAIDFVPTVVGKLFDLLMKTTSKMYSMFKSVVLATFTSESLDFTNPFWYAIAAILCFLITGAIPHNGKMKIHKNILSNATGIVAGIKAIQALAAMFSTWSNERLVNDLSSRTIALTELNNPTITADIDAVINLQRLAEVLRDEVKSHTLNPLMQPYNPILRNLMSALDKVISCCTRRKAIATKRTAPVAVILTGPPGCGKTTAAFALAKRLSQQKPSIISLDVDHHDTYTGNEVCIIDEFDSSDKVDYANFVVNMVNTNPMVLNCDLIENKGKTFTSKYVIMTSNTETPVKPTSRRAGAFYRRVMIVDVTNNAVDKWKSDNPGKAVPKWCFNKDFSHLSLSLRGTEPYSKEYVLDPTGRNHQSRRAPPPQQITLEQLAQKMVVQHTTNTSEFVTQAGDVPVFGFVCQNNEIDTVYNLLAAVKARYGANFNLYKGMVRTAHENSGCGAHVHVISREDNFRGKAFTVNRSRLESVPHLEGDSFRRSLGVVMSDKDVTTMFYYIKGKVINDQVSLTELPANQHVVTVHTVYDMAWALRRHLKWSGQWQLIKAAYEIMCYPDTAACALRNWMDSTDFSEEHVVTQFIAPGGTIILESCYGARMWATGQRLIRAGGLTEAGGPQGGVRFAGLGARNVPWSEILREFMTLISHIWSQIKGATVVLTALTFYLKRFRPRVEAKGKNKNKGPRKNTGVALTDDEYNDWKQSKAEKNLDLTVKDFLQLRHRAAMGADNTDAVKFRYWYSKKQKIYHDLENFPIIGRGGLKRELIRKGPLRPRGNDFYDEPDDWYSEGVIDGVTHKNAIVSVDDVDGMHKGYAIHIGHGVYISLKHVLTGNARILSEEPKGITISGELATFRLNNILPTAVPVGTNKPIKDPWGNPVSTDWQFKNYNTTSGNIYGACGSSCSLTRQGDCGLPYVDDHGVVVGLHAGSGGDKCPSRKLIVPYVKVDMRIRDTCTKESPTKTHKPTFSYRGLLGKETGEPRTIMKGTRLHVSPAHVDDYEECTHQPASLGAGDPRCPISLTGIMVNNLQPYTEASPGPDTATLNRVSKMLTSHMEGYVPKVHKTEEDSISAFYMLNHDTLCGPYIGARKKDHVKDGVLDKNLLDLLSSKWNRAKLGLALPHEYALGLKDELRPKDKVAVGKRRLIWGCDVGVSTVCAAAFKRVSESIMANHALGFIQVGINMDGPAVEDLFKRLERPKHDRYCVDYSKWDSTQPPKVTSQSIDILRHFTDKSPIVDSACATLKSNPIGIFNGVAFKVAGGLPSGMPLTSIINSLNHCLMVGSAVVKALEDSGVRVTWNIFDSMDLFTYGDDGVYIVPPLISSVMPKVFANLRQFGLKPTRTDKSDAEITPIPADEPVEFLKRTIVRTENGVRALLDRSSIIRQFYYIKAENTENWTVPPKRIDTPSRGQQLYNACLYASQHGEEFYTSKIVPLIERAVKLEGLHIEVPEFHQAVAAYNGYFNGTEGQPNQIAHASGGLGLSGEVFEN
What is the function of this protein?
Protease-polymerase p76 processes the polyprotein: Pro-Pol is first released by autocleavage, then all other proteins are cleaved.  Cleaves host translation initiation factor eIF4G1 and eIF4G2 thereby inducing a shutdown of host protein synthesis.  This shutdown may not prevent viral mRNA from being translated since viral Vpg replaces the cap.  May cleave host polyadenylate-binding protein thereby inhibiting cellular translation.  It is also an RNA-directed RNA polymerase which replicates genomic and antigenomic viral RNA by recognizing specific signals.  Transcribes also a subgenomic mRNA by initiating RNA synthesis internally on antigenomic RNA.  This sgRNA codes for structural proteins.  Catalyzes the covalent attachment VPg with viral RNAs (By similarity).
What are the official names of this protein?
Genome polyprotein.