PharMolix/UniProtQA huggingface dataset:
Protein: POG1_VANPO
Sequence: MGSSTTEPDVGTTSNIETTTTLQNKNVNEVDQNKKSEQSNPSFKEVVLKDIGLGEATDLENVSDDVFNNYLAIRLERERKEIELLKESNLEKLSVIIKNCIECNSFTDETMKRLINLVDNNYNNSVHFSPKSKRRKLESTSPPMSSSSVPNKETNNIQQSNSYQLRNNYDEEQENQKSQTQGSKSLLSRPNIYSFPPKQTQPASQQHVQLAAIVQRQSTLTTPLSSTYGSNSNNSMNTQLPLSDKSLRSNVQEKIVQQGSMSQRDIINGSNMSSQYSSQVYPPGYYQTRYGQQMVVVYPDSDSPQINQTSTIQHQQQLPHTYPPHYHQQQQLHQNQLVPQQHQQLQQQSISKHQLFGQKNPMSPQSHYLPNNESQNLGVINHRRSFSSGTYPVVNSRSKSPDRSMPLTVQKQMNFLIHTPKHPPPT
What is the function of this protein?
Transcriptional activator which promotes cell cycle recovery, after pheromone induced G1 arrest.  May also be involved in stress-resistance (By similarity).
What are the official names of this protein?
Transcriptional activator POG1.
What is the protein family that this protein belongs to?
Belongs to the POG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSN4_DANRE
Sequence: MASGVRQELAQLMNSSGSHKDLAGKYRQILEKALQFTDAEQLEALKAFVEAMVNENVSLVISRQLLTDFCAHLPNLPDDIAKVVCHFTLEKIQPRVISFEEQVASIRQHLATIYEKQEDWRNAAQVLVGIPLETGQKQYNVDYKLDTYLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRKFIEAAQRYNELSYKSIVHETERLEALKHALHCTILASAGQQRSRMLATLFKDERCQQLAAYGILEKMYLDRIIRGNQLQEFAAMLMPHQKATTADGSSILDRAVIEHNLLSASKLYNNITFEELGALLEIPPAKAEKIASQMITEGRMNGFIDQIDGIVHFETREPLPTWDKQIQSLCFQVNNLLEKISQTAPEWTAQAIEAQMSQ
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity).  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 4, Signalosome subunit 4.
What is the protein family that this protein belongs to?
Belongs to the CSN4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
Protein: EM1_ENSMI
Sequence: AGSKSRSRSRSRSRSKSPAKSASPKSAASPRASR
What are the official names of this protein?
Sperm protein EM1.
What are the subcellular locations of this protein?
Nucleus.
Protein: QUEF_ACIAD
Sequence: MSVEQSLLGKETEYPTTYSPSVLFPISRDAAREKYAQIEGISQGKDWWHVFELSWLNSDNIPQVAIGRITLPATSPYLIESKSLKLYFNSLNFHVFASKQELIDLVEKDLSQAANAKVSLELFDVDSLEISKPSGMCIDDLKPERLESHPDASLLKLDANEQHDADVTLYSHLLRSNCPVTGQPDWGTVFIRYTGRKHCYRSILAYIISYRQHNGFHEQCVEQIYADIWKNLQPEKLMVYATYTRRGGLDINPCRVSDLSWMPNPIRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_ECO5E
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEIITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTRWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: YO06_BPL2
Sequence: MQETVLMNKLYAELEVNKLGEHRKFKFIKEHLKDDQKTIDFLVNHLGYKRWQANQIAYSIQHRKNAYYKKKINTSTIDKES
What are the official names of this protein?
Uncharacterized 9.8 kDa protein, ORF6.
Protein: MUTT3_MYCTO
Sequence: MPSCPPAYSEQVRGDGDGWVVSDSGVAYWGRYGAAGLLLRAPRPDGTPAVLLQHRALWSHQGGTWGLPGGARDSHETPEQTAVRESSEEAGLSAERLEVRATVVTAEVCGVDDTHWTYTTVVADAGELLDTVPNRESAELRWVAENEVADLPLHPGFAASWQRLRTAPATVPLARCDERRQRLPRTIQIEAGVFLWCTPGDADQAPSPLGRRISSLL
What is the function of this protein?
May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool.  8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions.  MutT specifically degrades 8-oxo-dGTP to the monophosphate (By similarity).
What are the official names of this protein?
Putative 8-oxo-dGTP diphosphatase 3, 8-oxo-dGTPase, 7,8-dihydro-8-oxoguanine-triphosphatase 3, Mutator protein MutT3, dGTP pyrophosphohydrolase 3.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: PCO5_ARATH
Sequence: MPYFIQRLFNTCKSSLSPNGPVSEEALDKVRNVLEKIKPSDVGLEQEAQLVRNWPGPGNERNGNHHSLPAIKYLQLHECDSFSIGIFCMPPGSIIPLHNHPGMTVLSKLVYGSMHVKSYDWAEPDQSELDDPLQARPAKLVKDIDMTSPSPATTLYPTTGGNIHCFKAITHCAIFDILSPPYSSTHGRHCNYFRKSPMLDLPGEIEVMNGEVISNVTWLEEYQPPDNFVIWRVPYRGPVIRK
What is the function of this protein?
Catalyzes the oxidation of N-terminal cysteine residues (N-Cys), thus preparing the protein for N-end rule pathway-mediated proteasomal degradation, upstream of the N-end rule enzymes ATE1, ATE2 and PRT6 (Probable) (PubMed:29848548, PubMed:33207269, PubMed:32868422).  Controls the preparation of the group VII ethylene response factor (ERF-VII) proteins for degradation via the 26S proteasome N-end rule pathway (Probable) (PubMed:29848548, PubMed:33207269, PubMed:32868422).  Acts as an oxygen sensor that controls the stability of ERF-VII proteins, which are stabilized in flooding-induced hypoxia, and regulate transcriptional adaptation to these adverse conditions (Probable) (PubMed:29848548).
What are the official names of this protein?
Plant cysteine oxidase 5, AtPCO5.
What is the protein family that this protein belongs to?
Belongs to the cysteine dioxygenase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MNMA_PELTS
Sequence: MEKTKVVVAMSGGVDSSVTAALLLEQGFEVIGITMQIWNPGEEAESKGERTCCSLTAIDDARRVADKLGISHYVLNFRSIFEEKVIDYFTSEYLRGRTPNPCIACNRYVKFEALLDRALSIGAEYIATGHYARLGYSGEYGRYTVRRPVDRRKDQTYVLYGMTQRQIARTMMPLGNYTKGQVRKIAEDFGLPVAGKAESQEICFILDDDYRRFLREKAAGIKPGPFLNMKGEVIGRHNGIPFYTVGQRRGLGLAAGERLYVVKIDPENNAITLGPEEAVWGRSLIAADVNLILYESLEEPLEVEAQVRYNARTSPATLVPLPEGRVGVHFHTPQRSITPGQAVVFYRGDYLIGGATIESTGDFFR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FK133_ARATH
Sequence: MSRSAASSVGSITGESPQKKLLQSASSSSSLAILHDEIAVSCFARVPRCYYPAISLVCRNFRRLMASPEIYIERSVIRRTENILYVAIRSEATKTLSWYTLNLKPFGTTEISHRLVPVPSFPSIPGYGTTIISSGSETYVIGGCIDGELVSTVSVIDCRSHTCRFLPNMKEPRKCAAVGLIDGKLYVVGGCNAPSLSWVEVFNFKKRTWESVLSLDNVDMDEQMNFFVMNDKIYRIGQNTMFVYDPKKGRFEEDLALGRLWFNESCPIDNVLYGFYCMNQILAYDLVVGMGTVFWGLEGLPEGLQSCTGRMVNHGGRLAILFKKSPTEIWRTEIAIERAEEGGYISGKFLWSNHVLTLTDSFIIERALAVTV
What are the official names of this protein?
F-box/kelch-repeat protein At4g14905.
Protein: DNB2_ADE41
Sequence: MAGRQREHPTVTPYLQETSPERPPPLPPKKKLRKNLQVPEQVHAPALSPEVVPDSEEDEEVLYHGFSYPGVEVVQKGNGKRQIRRLEKTVIPRDLTPPEEEENNQSGSSKAVTMLITNPQVDPLVSAWEKGMELMNVLMEKYHVENDEKTAFKFLPEQNAVYRKICQTWLNEERRGLSLTFTTQKTFTELMGRFLAAYVETYAGVKHHNWDTTGCAVWAHGCTREEGVLRCFHGREMIQKEQVVEVDVGSENGQRALKEQPSKTKVVQNRWGRSVVQIKNDDARCCAEDVSCGNNMFSSKSCGLFFSEGLKAQIAFKQMQAFLQAEYPQMQRGQQRILVPLRCECLNKKDLVPQLGRQMCKVTPFALSGAEDLKTSEVTDKSALASILHPCVLVFQCANPVYRNSRGSAGPNCDFKISAPDVISALQLVRQFWKENVEDPLPKLIIPEFKWSTRLQYRNVALPTGHGDAEVEPF
What is the function of this protein?
Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers.  Also enhances the rate of initiation.  Released from template upon second strand synthesis.  Assembles in complex with viral pTP, viral pol, host NFIA and host POU2F1/OCT1 on viral origin of replication.  Covers the whole ssDNA genome during synthesis.  The complementary strand synthesis induces its relese from DNA template.  May inhibit cellular transcription mediated by the interaction between host SRCAP and CBP.
What are the official names of this protein?
DNA-binding protein, DBP, Early 2A protein, Early E2A DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E2A DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Accumulates in infected cells.
Protein: MDAR4_ARATH
Sequence: MGRAFVYVILGGGVAAGYAALEFTRRGVSDGELCIISEEPVAPYERPALSKGFLLPEAPARLPSFHTCVGANDEKLTPKWYKDHGIELVLGTRVKSVDVRRKTLLSSTGETISYKFLIIATGARALKLEEFGVEGSDAENVCYLRDLADANRLATVIQSSSNGNAVVIGGGYIGMECAASLVINKINVTMVFPEAHCMARLFTPKIASLYEDYYRAKGVKFIKGTVLTSFEFDSNKKVTAVNLKDGSHLPADLVVVGIGIRPNTSLFEGQLTIEKGGIKVNSRMQSSDSSVYAIGDVATFPVKLFGEMRRLEHVDSARKSARHAVSAIMDPIKTGDFDYLPFFYSRVFAFSWQFYGDPTGDVVHFGEYEDGKSFGAYWVKKGHLVGSFLEGGTKEEYETISKATQLKPAVTIDLEELEREGLGFAHTVVSQQKVPEVKDIPSAEMVKQSASVVMIKKPLYVWHAATGVVVAASVAAFAFWYGRRRRRW
What is the function of this protein?
Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process (PubMed:16146528).  Involved in the detoxification of H(2)O(2) that escapes the peroxisome and causes oxidative damage to oil bodies (PubMed:17449810).
What are the official names of this protein?
Monodehydroascorbate reductase 4, peroxisomal, AtMDAR4.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: Y1539_MYCBO
Sequence: MIPVKVENNTSLDQVQDALNCVGYAVVEDVLDEASLAATRDRMYRVQERILTEIGKERLARAGELGVLRLMMKYDPHFFTFLEIPEVLSIVDRVLSETAILHLQNGFILPSFPPFSTPDVFQNAFHQDFPRVLSGYIASVNIMFAIDPFTRDTGATLVVPGSHQRIEKPDHTYLARNAVPVQCAAGSLFVFDSTLWHAAGRNTSGKDRLAINHQFTRSFFKQQIDYVRALGDAVVLEQPARTQQLLGWYSRVVTNLDEYYQPPDKRLYRKGQG
What are the official names of this protein?
Uncharacterized protein Mb1539.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: UNG_BACAH
Sequence: MKHVLKNDWGPLLAPEFEKEYYRELDVFLKEEYSIHVVYPKIEDIFNALEYTSYENTKVVILGQDPYHGPNQAHGLSFSVQPGVKTPPSLLNMYKELRDEYGYDIPNNGYLVKWAEQGVLLLNTVLTVRQGEANSHKGKGWEHFTDRVIELLNEREKPVIFILWGRHAQAKKKLITNSNHHIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEREIDWEIPNL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1433C_SOYBN
Sequence: MASTKERENFVYVAKLAEQAERYEEMVEAMKNVANLNVELTVEERNLLSVGYKNVVGARRASWRILSSIEQKEEAKGNDVSVKRIKEYRLKVESELSNICSDIMTVIDEYLIPSSSSGEPSVFFYKMKGDYYRYLAEFKSGDERKEAADHSMKAYQLASTTAEAELASTHPIRLGLALNFSVFYYEILNSPERACHLAKQAFDEAISELDTLSEESYKDSTLIMQLLRDNLTLWTSDIPEDGEEQKVDSARADGGDDA
What are the official names of this protein?
14-3-3-like protein C, SGF14C.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: HSPC1_RICBR
Sequence: MKIKAYIPAIAAVILSSNATLANQNQAYNSNHTTSLHQAIELLDNQITNIDNLFKNKLPFYESNSIKSKFITKDKQYIIIMEVPGFDKDHIKIKVNGNKLFVKGNIEDKNKADDSNNYMNKNFNYVISLYEDVDQKNISSSLKNGILTITLPRIEVKEQDAKEIPIN
What are the official names of this protein?
Small heat shock protein C1.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: NUOI_WOLPM
Sequence: MTDTSFKYFMLKKLAWYWSFVELIKGFVITLKYMFKPKVTLRYPMEKGPLSPRFRGEHALRRYPNGEERCIACKLCEVICPAQAIVIEAEEREDGSRRTTRYDIDMIKCIYCGLCQEACPVDAIVEGPNFEFATETREELMYNKEKLLRNGEVWEDAIALRLKKNRPYY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DERL1_HUMAN
Sequence: MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGDQ
What is the function of this protein?
(Microbial infection) In case of infection by cytomegaloviruses, it plays a central role in the export from the ER and subsequent degradation of MHC class I heavy chains via its interaction with US11 viral protein, which recognizes and associates with MHC class I heavy chains.  Also participates in the degradation process of misfolded cytomegalovirus US2 protein.
What are the official names of this protein?
Derlin-1, Degradation in endoplasmic reticulum protein 1, DERtrin-1, Der1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MARK2_RAT
Sequence: MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMLRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRSSDQAVPAIPTSNSYSKKTQSNNAENKRPEEETGRKASSTAKVPASPLPGLDRKKTTPTPSTNSVLSTSTNRSRNSPLLDRASLGQASIQNGKDSTAPQRVPVASPSAHNISSSSGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPFGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLNEPESKDRVETLRPHVVGGGGTDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHERYMLLCVHGTPGHENFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
What is the function of this protein?
Serine/threonine-protein kinase.  Involved in cell polarity and microtubule dynamics regulation.  Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4 and RAB11FIP2.  Phosphorylates the microtubule-associated protein MAPT/TAU.  Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly.  Regulates epithelial cell polarity by phosphorylating RAB11FIP2.  Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX.  Regulates axogenesis by phosphorylating KIF13B, promoting interaction between KIF13B and 14-3-3 and inhibiting microtubule-dependent accumulation of KIF13B.  Also required for neurite outgrowth and establishment of neuronal polarity.  Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.  Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).  Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery.  Essential for the asymmetric development of membrane domains of polarized epithelial cells.
What are the official names of this protein?
Serine/threonine-protein kinase MARK2, ELKL motif kinase 1, EMK-1, MAP/microtubule affinity-regulating kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Lateral cell membrane. Cytoplasm, cytoskeleton. Cytoplasm. Cell projection, dendrite. Note=Phosphorylation at Thr-539 by PRKCZ/aPKC and subsequent interaction with 14-3-3 protein YWHAZ promotes relocation from the cell membrane to the cytoplasm.
Protein: YBDG_SHIFL
Sequence: MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIILHWVVLRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTCAQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLLIGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGAVIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRFLDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEYLRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEEFGLRLHQSPTGNDIRSLAGAFKQ
What is the function of this protein?
Mechanosensitive channel of miniconductance that confers protection against mild hypoosmotic shock.
What are the official names of this protein?
Miniconductance mechanosensitive channel YbdG.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMB_LEUMM
Sequence: MHLRSKPWASDWLAEHSDIVIDQDRATAQIGQWQSLFDQEQPIHLEIGSGKGQFILGMALAHPEINYIGMEIQETAIAIAARKSFDQVGTLPNLRYIYGNGNGVETYFEKGEVSKVYLNFSDPWPKKRHESRRLTYKSFLKSYEAVLPEHGEVEFKTDNRHLFEYSMVSFMDYGMRWTPEDYTLDLHADEDKVQGNVETEYEQKFMAKGQPIYKIKAHF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RL24_BURCH
Sequence: MNKIRKGDEVIVVTGKDKGKRGVVLAVGAEHVTVEGINLVKKHVKPNPMKGTTGGVEAKTMPLHISNVALVDANGKASRVGIKVEEGKKVRFLKTTGAVLSA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ATPE_EUCGG
Sequence: MTLNLCVLTPNRIVWDSEVKEIILSTNTGQIGVLPNHAPIATAVDIGILRIRLNDQWLTMALMGGFARIGNNEITILVNDAEKGSDIDPQEAQETLELAEANLRKAEGKRQTIEANLALRRARTRVEAINAIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SSUR_BURCJ
Sequence: MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENLRRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVTFPCYSWHHTVVVPKGHPLVGRENLTLEEIAEYPIITYDQDFTGRSHIDQAFTQAGAVPDVVLTAIDADVIKTYVELGMGIGVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEIAGLLREAV
What is the function of this protein?
Transcriptional regulator that is essential for the utilization of a number of organic sulfur sources of either environmental or human origin (PubMed:21317335).  Required for aliphatic sulfonate utilization (PubMed:16997956).  Binds to DNA at target promoter regions (PubMed:16997956, PubMed:21317335).  Targets include the ssuDBC operon, the tauABC operon, three tauD-type genes and atsA (PubMed:16997956, PubMed:21317335).
What are the official names of this protein?
HTH-type transcriptional regulator SsuR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GLPK_MYCMS
Sequence: MTDSKKYILTLDEGTTSARALITDKQGNIIAVEQSEFTQYFPKEGWVEHDAIEIWNTQRSALVQVLNKSGIDPSQIEAIGITNQRETAVIWNKETGLPIYNAIVWQDQRTADYCQTFDKDTLEMVKQRSGLIINPYFSGTKVKWILDNVPNARQLAKEGKLMFGTINTWLIYRLTGGEVFVTDHTNAQRTLLYNIHTNDWDDELLKLFDIPRNILPEIKSCSEVYGYTFKGLFSKGNEQRIKIASSIGDQQSALFGQLCLEKGQVKVTYGTGCFILTNTGEEIVKSNHGLLTTVAYSFKDKVYYALEGSVMIAGAAVQWLRDNLRIVYNAIETEWYADQVKDDRRVYVVPSFTGLGSPYWDSFSRGAIFGLDRGTRREHIVRATLEAIVYQANDVVDAMRKDMKKPIEIFKVDGGAANNKFLMQFQSNISQSKVIKPTNVETTAMGAAFMVGLAVGYWENAEELKKTYKVHFELTPELSKPEVDKLIKGWKVAVQRTFKWVEEIE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: MNHF1_STAAW
Sequence: MNHNVIIVIALIIVVISMLAMLIRVVLGPSLADRVVALDAIGLQLMAVIALFSILLNIKYMIVVIMMIGILAFLGTAVFSKFMDKGKVIEHDQNHTD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit F1, Mnh complex subunit F1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AT_BPPAM
Sequence: MIVVRKALPEEHKEILQVAKQSKYTKDFSNQVMFSSEAAYNKGWIHVAEHEGEIRGFYCIREKVRAPETVLYFIGVAQEAKGLGLGKKLIEHIMATTRHRRLTLNVNKQNEEARAFYDRLGFTVAGESLGGEGLALFKEW
What is the function of this protein?
Acetylates 5-aminomethyl-2'-deoxyuridine (5-NmdU) to produce 5-acetylaminomethyl-2'-deoxyuridine (5-AcNmdU) on DNA as a step in the pathway leading to thymidine hypermodifications in the viral genome (PubMed:34522950).  As a final result of the pathway of hypermodification, 5-acetylaminomethyl-2'-deoxyuridine (5-AcNmdU) substitutes for a subset of thymidines in the viral DNA (PubMed:34522950).  These modifications probably prevent degradation of viral genome by the host restriction-modification antiviral defense system (PubMed:34522950).
What are the official names of this protein?
5-NmdU N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: HHEX_DANRE
Sequence: MQFQHPHAPLYAPAPAPPAHPTPFYIEDILGRTGSSSGPVVPTPTLPSPNSSFTSLIPSYRTPIYELTPIHPVLSQYASMYPFQRSVGDFAHALIRHDPLGKPLLWSPFIQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPPSTGKREAEDSDTRRLSDAAARARELESGASTDSEELLDIEDEHQFTL
What is the function of this protein?
Recognizes the DNA sequence 5'-ATTAA-3' (By similarity).  Transcriptional repressor.  Regulates the differentiation of both endothelial and blood cells.  Plays a role in embryonic dorsoventral patterning by regulating bmp expression.  May establish anterior identity.  Functions in the embryo to regulate liver development.  Functions extraembryonically to generate organ chirality.
What are the official names of this protein?
Hematopoietically-expressed homeobox protein hhex, Homeobox protein hex.
What are the subcellular locations of this protein?
Nucleus.