PharMolix/UniProtQA huggingface dataset:
Protein: IMA1B_ORYSJ
Sequence: MSLRPSERAEVRRSRYKVAVDADEGRRRREDNMVEIRKSRREESLLKKRRDGLPAAAAAAAAASPLLAHSSALQQKLEGLPAMVQAVQSDDSAVQLEATTQFRKLLSIERSPPIEEVINTGVVPRFIAFLQREDYPQLQFEAAWALTNIASGTSDNTKVVVESGAVPIFVKLLSSPSEDVREQAVWALGNVAGDSPKCRDLVLASGGLYPLLQQLNEHAKLSMLRNATWTLSNFCRGKPQPNFEQVKPALSALQRLIHSQDEEVLTDACWALSYLSDGTNDKIQAVIESGVFPRLVELLMHPSASVLIPALRTVGNIVTGDDMQTQCVIDHQALPCLLNLLTNNHKKSIKKEACWTISNITAGNREQIQAVINANIIAPLVHLLQTAEFDIKKEAAWAISNATSGGTHDQIKYLVAQGCIKPLCDLLVCPDPRIVTVCLEGLENILKVGEAEKNLGAGDVNSYAQMIDDAEGLEKIENLQSHDNTEIYEKAVKMLESYWLEEEDDAMPSGDNAQNGFNFGNQQPNVPSGGFNFG
What is the function of this protein?
Functions in nuclear protein import.  Binds specifically and directly to substrates containing either a simple or bipartite NLS motif.  Promotes docking of import substrates to the nuclear envelope.  In conjunction with importin beta-1, mediates the nuclear envelope docking, and the subsequent translocation into the nucleus of the constitutive morphogenetic 1 (COP1) protein containing bipartite NLS motif.
What are the official names of this protein?
Importin subunit alpha-1b.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: THRC_BUCBP
Sequence: MKLYNLKKKQDQVNFSKAVKLGLGKNQGLFFPKELPILTKEQLYKLLKMDFLTRSSKILSMFIGDEIHYSELTKRIKNAFSFTTPKIVSISKNIACFELFHGPTLAFKDFGARFMAQILSFLNHDKNDTITILTATSGDTGAAVAHAFFKMKNVRVIILYPKGKISELQEKLFCTLGENIITIAVNGSFDECQKLVKQAFNDDQLRIETGLNSANSINISRLLAQICYYFEAFALLTKKQQKNLVISVPCGNFGNLTAGLLAKALGLPIKSFIASTNSNDTVPRFLKTGFWKPNNTVSTISNAMDISQPNNWPRVEELFKRKFWSLKTLKYGSVSDILTKKSLKKLAFLGYVSEPHAAVAYYTLKNKLKQNEFGLFLGTAHPAKFKKTIEKILQITLFLPSKLRNQIKLPLLSHNIRPDFSKLKKFLLEK
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: GP68_BPT4
Sequence: MLLIPETHELVLENVEALIPEAQGRFDELSSALNKDDINTIVENMLDDETDLAVALASINENMPLNEFIVKHVSARGEITRTKDRKTRERNAFQTTGLSKAKRRQIARKATKTKIANPAGQSRAQRKRKKALKRRKALGLS
What is the function of this protein?
Plays a role in the phage head size determination.  About ten copies of gp68* are found in the mature phage head.
What are the official names of this protein?
Prohead assembly protein gp68, Gene product 68, gp68.
What are the subcellular locations of this protein?
[Protein gp68*]: Virion.
Protein: RIBA_PICTO
Sequence: MIEFYSKARLPSRFGSFEIYVFKNDENKDHAVIVHGDVRGKSDVPVRIHSECLTGDVLGSMRCDCRDQLIESLKYIGSQPYGMLIYMRQEGRGIGLLNKIRAYNLQDQGLDTVEANLEQGLPVDERKYDYAVDVIKYFNIESIQLITNNPEKLKYLEEHGIKITKRIPIIIPPTKFDEFYLETKRERMGHLF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: LPXB_CUPPJ
Sequence: MVDAAIRGTLPAGTGTNASQRGTIAMVAGEASGDLLASLMLGGLKARLGDTVSYAGIGGKRMMTEGFVSQWPMETLSVNGYVEVLGSLREILATRRAIRDSLLANPPLCFIGVDAPDFNFGLEVPLRRAGIPVVHFVSPSIWAWRGGRIRTIARAVDHILCLFPFEPEIYAKAGIPATYVGHPLADVIPMVPDVAGARAALDLPAGCRVVAVLPGSRQSEVRNLGATFFAAMARMHRMDPNLAFVLPAASAPLRAIVEELHQQYPELRLTIVDGNSHQAMEAADVVLLASGTATLEAALYKKPMVISYKVPWLTAQIMKRQGYLPYVGLPNILSGRFVVPELLQDDATPEALARETLLQLNDQGNIAFLYEHFTRMHETLKCNTAQLAADVVVDLMRSRGLV
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: COAD_LISW6
Sequence: MGNKIAVIPGTFDPITNGHLDIIERAAKIFDVLYVAVLNNSSKKPLFTVEERMEMIKQVTAHLPNVAVESASGLTVDYAAKRGATAIVRGLRAVSDFEYEMQIASMNRTLNAEIETFFVMTNTKYSFLSSSMVKEVAQYQGDISELVPEMVNRAIQVKFNK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFTPD_MACMU
Sequence: MLLFLLSALVLLTQSLGYLEADMKTYSQRTAPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGKAGMPGEAGPVGPKGDNGSIGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGPAGPKGDRGVPGERGAPGNAGAAGSAGVMGPQGSPGARGPPGLKGDKGVPGDKGAKGESGLPDVASLRQQVEALQKQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLVCTQAGGQLASPRSAAENAALQQLVIAQNEAAFLSMTDSKMEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCEF
What is the function of this protein?
Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins.  Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response.  May participate in the extracellular reorganization or turnover of pulmonary surfactant.  Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties (By similarity).
What are the official names of this protein?
Pulmonary surfactant-associated protein D, PSP-D, SP-D, Lung surfactant protein D.
What is the protein family that this protein belongs to?
Belongs to the SFTPD family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Protein: PNP_METCA
Sequence: MNPIRKQFQYGAHTVSFETGEIARQADAAVMVDMAGTVVLVTVVGRKDASPHGDFFPLTVNYQEKAYAAGRIPGGFFKREGRPSEKETLTARLIDRPIRPLFPDGFTHEVQVVATVMSLNPEVDPDIPSMLGASAALTLSGLPFKGPIGAARVGFVNGAYVLNPDGSVVEGSELDLVVAGTANAVLMVESEAKILPEEVMLGAVVFGHEQMQTAIRAINELAEEVGVTPWPWEPSAVDAALVAAVDELARAGLGEGYNIADKQLRQQKLKEVRKAVIDALTAEGAHDENAVKRQIEKLEEEIVRSNILHHGKRIDGRDLSTVRPITIRTGVLPRTHGSALFTRGETQALVVATLGTGRDAQLIDALEGEYKENFMLHYNFPPYCVGETGAIGSPKRREIGHGRLAKRGVQAIMPTMDEFPYVIRIVSEITESNGSSSMASVCGSSLALMDAGVPTKGAVAGIAMGLILEGEEFAVLSDIMGDEDHLGDMDFKVAGTRDGVTALQMDIKIDGITPEIMRQALHQAREGRMHILDKMAQALPAPRSEMSDYAPRITSFTIDPSKIREVIGKGGATIRAITEETGTSIDISDDGVVKIASVDKQAGLEARRRIEDITAEVEVGKVYEGKVARLMDFGAFVTILPGKDGLVHISQISDEHVEKVSDKLAEGDMVKVKVLEIDRQGRVRLSMKAVE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR43B_DROME
Sequence: MFGHFKLVYPAPISEPIQSRDSNAYMMETLRNSGLNLKNDFGIGRKIWRVFSFTYNMVILPVSFPINYVIHLAEFPPELLLQSLQLCLNTWCFALKFFTLIVYTHRLELANKHFDELDKYCVKPAEKRKVRDMVATITRLYLTFVVVYVLYATSTLLDGLLHHRVPYNTYYPFINWRVDRTQMYIQSFLEYFTVGYAIYVATATDSYPVIYVAALRTHILLLKDRIIYLGDPSNEGSSDPSYMFKSLVDCIKAHRTMLNFCDAIQPIISGTIFAQFIICGSILGIIMINMVLFADQSTRFGIVIYVMAVLLQTFPLCFYCNAIVDDCKELAHALFHSAWWVQDKRYQRTVIQFLQKLQQPMTFTAMNIFNINLATNINVAKFAFTVYAIASGMNLDQKLSIKE
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.
What are the official names of this protein?
Odorant receptor 43b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ESCO2_MOUSE
Sequence: MMATCTPRKRKRYTLNADNDDSLLTDISSSKLRCAENLFPSPNKKHNYQSSVQKEDKSCSHQLHFPSSPLKTTENSRFSFANHSSLFKPAMSTVSFYSKEKYYLNPLERKLIRECRSICLATESGDKPIPSVTENIQRKPVCTKKNKKKQKSLTAKYQPNYKHIKSKSRNLKNSKPNQVTYKPVVDQENSCFPAKNYPNSPPRVLSQKIKPQVTLQGGAAFFVRKRNSLKKLPLEDKPLLLQKNLPEVPEGAPEAKQIPKSLLVDEKSSVKVQNARSKNEEKLRKNPSGAVVSSKECNLDKHDFPSENSLDENKTISPESVYPIFNVSSVNTKRPEEQSSVGSTACTNFLKQTNVPKNINSRDTNKGGKDQLVIDAGQKHFGTTVCKSCGMIYTASNPEDEIQHLQHHHRFLEGIKFVGWKRERVVAEFWDGKIVLVLPRDPSYAIKKVEDVQELVDLELGFQQTVPVCPDKTKTFLFIDEKRVVGCLIAEPIKQAFRVLSEPSASKECSRAWRCSDVPEPAICGISRIWVFRLKRRKRIARRLVDTVRNCFMFGCFLSTNEIAFSDPTPDGKLFATKYCNTPNFLVYNFHN
What is the function of this protein?
Acetyltransferase required for the establishment of sister chromatid cohesion.  Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together.  In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase.  Acetylates the cohesin component SMC3.
What are the official names of this protein?
N-acetyltransferase ESCO2, Establishment of cohesion 1 homolog 2, ECO1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ECO subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Nuclear in interphase cells, excluded from chromosomes during metaphase but reassociates with chromosomes in telophase.
Protein: MAST_VESCR
Sequence: LNLKALLAVAKKIL
What is the function of this protein?
Mast cell degranulating peptide.  Activates G proteins that couple to phospholipase C.
What are the official names of this protein?
Mastoparan-C.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Mastoparan subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MKAR_PICGU
Sequence: MLRLIDSISDNCTVKTALYGALLLGVYKLTTFALSLVSLVLDLWVLPPVNFAKYGAKKGKWAVITGASDGIGKEYATQLAAKGLNVVLVSRTESKLVALAEEIESKYKVSTKVLAFDVSLDAESSYEDLAATIADLPVTVLVNNVGQSHSIPVPFLETDEKELRNIITINNTATLKITQVVAPKIVHTVASEKKKTRGLILTMGSFGGLLPTPYLATYSGSKAFLQSWSNALSGELQPQGVDVELVISYLVTSAMSKIRRSSASIPNPKAFVKSVLRNVGRRVGAQERFGTTTPYWAHAFMHFGIVNSVGVYSKIANSLNLGMHKSIRSRALKKAARQKKD
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: BAG2_BOVIN
Sequence: MAQARISAKANEGRFCRSSSMADRSSRLLESLDQLELRVEALREAATAVEQEKEVLLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRSPQQQESLKHATRIIDEVVSKFLDDLGNARSHLMSLYSACSSEVPAGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIENADKAIKLLEHSKGAASKTLQQNAEARFN
What is the function of this protein?
Co-chaperone for HSP70 and HSC70 chaperone proteins.  Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release.
What are the official names of this protein?
BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2.
Protein: ATPE_GEOKA
Sequence: MKTIHVSVVTPDGPVYEDDVEMVSVKAKSGELGILPGHIPLVAPLEISAARLKKGGKTQYIAVSGGFLEVRPDKVTILAQAAERAEDIDVLRAKAAKERAERRLQSQQDDIDFKRAELALKRAMNRLSVAEMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ASTD_SALTY
Sequence: MTLWINGDWITGQGERRRKTNPVSAEILWQGNDANAAQVAEACQAARAAFPRWARQPFAARQAIVEKFAALLEAHKAELTEVIARETGKPRWEAATEVTAMINKIAISIKAYHARTGAQKSELVDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTLIFKPSELTPWTGETVIKLWERAGLPAGVLNLVQGGRETGQALSSLDDLDGLLFTGSASTGYQLHRQLSGQPEKILALEMGGNNPLIIEDAANIDAAVHLTLQSAFITAGQRCTCARRLLVKQGAQGDAFLARLVDVAGRLQPGRWDDDPQPFIGGLISAQAAQHVMEAWRQREALGGRTLLAPRKVKEGTSLLTPGIIELTGVADVPDEEVFGPLLNVWRYAHFDEAIRLANNTRFGLSCGLVSTDRAQFEQLLLEARAGIVNWNKPLTGAASTAPFGGVGASGNHRPSAWYAADYCAWPMASLESPELTLPATLSPGLDFSRREAV
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: ATP6_GEOSW
Sequence: MHHEAPLYEFLGLTFNLANVLMITITSVIVFIIAVAATRNLSMKPTGMQNFLEWVVDFVKGIIKSNMDWKTGGRFHLLGMTLIMYIFVANMLGLPFSIVIDGKLWWKSPTADPVITLTLAIMVVALSHYYGIKLRGFQEYAKGFVSPMWILFPLKIIEEFANTLTLGLRLYGNIYAGEILLALLAGGLATGVGGTIAAIIPTIAWQAFSIFVGAIQAFIFTMLTMVYMAHKVSHDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL28_CHESB
Sequence: MSRACELTGKAVMSGNNVSHANNKTRRRFLPNLCDVTLMSEALGQSYRLRVSANALRSVEHRGGLDAFLLKAKSNELSQRARLLKKQVAKKLTEQTEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NU2C1_COFAR
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSSSDQKDIPWLYFIPSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDFITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGVRFVREIPTSLSISEMFGFFKTPWTCRREILSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNGWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVLIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDSLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FIMBG_DICNO
Sequence: MNKQRFLFAAKISGIHFLLSLVVALALAGLIFFVWYPFPYQKIMGSFK
What are the official names of this protein?
Fimbrial assembly protein, serogroup G1.
Protein: RSMG_FRATF
Sequence: MDIMKDKIRQALSELDILATEVQIDQWLDYLKLLEKWNKVYNMTAIKNIDEMLVKHLFDSLAVAKYIKGDSTVDVGTGGGLPGVVLAILYPQHQFTLVDSVGKKIMFLKNVKKSLSLNNINPLNTRIENLEGNFDNIISRAFSSVDTFYELCKHFLTEHNQMLAMKGRDLEERNLESLPLNIEKYSIKVPFLNAERNLIVMRKKL
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAHM6_RAT
Sequence: MEKFKAVLDLQIKHRSALGYGLVTLLTAGGEKIFSTVVFQCPCTATLNLTYGLVFLLVPALALFLLGYALSARTWRLLTGCCSRSASTRSSSGLRSTLVCAQVSAVAALAPLTWVAVALLGGSFYQCAVSGSTRLASYLCKDRNHSCIAKLPQVPCNKQEAEMQEILSQLKAQSQVLGWVLIAAVIFLLLVFKCVSRCFSPVSYLQLKFWEIYLEKEKQILQSQAAEHATQLARENIRSFFECSKPKECNTPSRKDWQQISALYTFNSKNQFYSMLHKYVSRKEVSSSLHSVEGDVVVPVLGFVDDAAMANTHGV
What is the function of this protein?
Pore-forming subunit of a voltage-gated ion channel.
What are the official names of this protein?
Calcium homeostasis modulator protein 6, Protein FAM26F.
What is the protein family that this protein belongs to?
Belongs to the CALHM family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRM1_SACS2
Sequence: MKLKEVTEGKVRIFVPDPTGYMVEGKFDPSWAPVFYNPKMTFNRDLSVIVVSILKPKIIVDALSATGIRGIRYYVESWKSEQLILNDKNPNATSLIQINAKNNGIENAKIYNKDANALLYEVKSDYIDIDPFGSPAPFILSSLNAATRNGIVAFTATDLSPLEGSSPTSCRRKYDAINHKLSSSKELGLRVLIGKIIREAAILEKTVYPLFSFYADYYYRLFVRVENGARKADDNINKHLKYFGECPRCGFQTFVEENCKTKCPVCGEIFSIIGPLYIGPLYSMEFLKRIMDLYSNFNYLTSFNRIQKLLNVIEKEARFKNVFYNISKLASKLKISAIPPIESILECLGDASRTHFAPTGIRTDKEYEEITKCIKSLR
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: HYCC2_MOUSE
Sequence: MLGSERAVVEEWLSEFKALPDTQITSYAATLHRKKALVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELIWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPASSYQSLCRMGSRVCVSGFPRQHEKQWKELCGRIVLDPEFMVQLLTGVYYAMYNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSSQEGQKVLKVEVTPTVPRISRTAITTASIRRHRWRREGAEGLNGGEESLNMNDADEGFSSGASLSSQPHGTKPPSSSQRGSLRKVATGRSAKDKETALAIKSNESPRDSVVGKQFVQQQADLSIDSVELTPMKKHLSLPAGQVVPKTNSLSLIRTASASSSKSFDYVNGGQASTSIGVGTEGVTNLAATNANRYSTISLQEDRLGHAGEGKELLSPGAPLTKQSRSPSFNMQLISQV
What is the function of this protein?
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane.
What are the official names of this protein?
Hyccin 2.
What is the protein family that this protein belongs to?
Belongs to the Hyccin family.
Protein: CH10_PELPD
Sequence: MKLRPLHDRILVKRVEEETKTAGGLFIPETAKEKPQRGEVVAAGNGKKTEDGKVLPLDVKVGDKVLFGKYSGTEVKVDGEDFLMMREDDILAVVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2336_METCA
Sequence: MNSEAEFLANHFLIAMPGLTDPHFAKTVTLVCQHNADGALGIIINRPSELKLSDIMRQMEIDLKVAELGDLPVFFGGPVHPERGFILHEPATVWASTLVVSERLALTTSRDILEAVGRGEGPRRMLLALGYAGWGQGQLEREIIDNSWLNAPSDNAVIFEHPPGRRWKAAADLVGVDISLLTSQAGHG
What are the official names of this protein?
UPF0301 protein MCA2336 2.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: YRA2_YEAS7
Sequence: MDKAFDEIIGNSHTDSSSNHKVTRYRRRDLRNELGPRLGFAPSDAASRSKDRLYREREEPPLPKRIRISKIPLDVSDYTLDDMIKEFGSPIFSKIFDNKEDRTCIYEFEDPEVLEKIVERYNGHELHNAKIEVEIYQPQRKHSRMNAHNRRKQTAQEHGRDRPGSHYRQKPNRVSKKNKGREKNNTPTSVEALDAELDAYMKG
What is the function of this protein?
Involved in export of poly(A) mRNAs from the nucleus.  Recruited to the coding sequences as well as poly-A sites of active genes (By similarity).
What are the official names of this protein?
RNA annealing protein YRA2.
What is the protein family that this protein belongs to?
Belongs to the YRA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAA_THEAB
Sequence: MKYTIISGPTAVGKTDIVLEIASQINANIISVDSRQIYKLMDIGTAKPSKEEKSKVTHYLIDHIYPDEYYNAFLFRQDALKIRDKLVNEGIVPLFVGGTGLYIDSLVRGFFEGVPKDEKLRKELSEMEKNEPGILRSMLEKYDPQAAQKIHPSDIKRTIRALEVYFKTGKKISQLQTQSEYSKDYKILVLDRYRDELYERINLRVDKMIKEGLVDEVKSLLEKYPKDLNAFQTIGYKEIIRYLENTYDLNTAVHLIKKNTRHYARRQIIWLRRYKQAKWINLSEISRKKAIEEIKKFILEV
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PROF1_TOBAC
Sequence: MSWQTYVDDHLMADIEGQQGHHLAAAAILGHDGSVWAQSSTFPKFKPEEITNIMKDFDEPGHLAPTGLFLGGAKYMVIQGEPGAVIRGKKGSGGITIKKTNQALIFGIYEEPVTPGQCNMVVEKIRDYLVDQGY
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-1.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ILVC_BORPD
Sequence: MKVFYDKDCDLSLVKGKTVAIIGYGSQGHAHALNLHDSGVKVVVGLRKGGASWNKAANAGLEVKEVAEAVKVADVVMMLLPDENIAAVYRNEVHANIKAGAALAFAHGFNVHYGQVVPRDDIDVIMIAPKAPGHTVRSTYTQGGGVPHLVAVHQDKSGSARDVALSYASANGGGRAGIIETDFREETETDLFGEQAVLCGGTVELIKAGFDTLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEFGEYETGPKIVTEQTRQAMRDALVAIQTGEYAKKFILENAAGAPTLTSRRRINAESQIEQVGGKLRAMMPWIAANKLVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.