PharMolix/UniProtQA huggingface dataset:
Protein: STRH_STRPN
Sequence: MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTENQPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEVSSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEAKAEADKPATEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVAFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYTAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKREVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQGLKPAVTHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGLAPTTEVKPRLDIQEEEIPFTTVTCENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGKEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAEESKVLPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED
What are the official names of this protein?
Beta-N-acetylhexosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: DEF_BUCCC
Sequence: MSIRKILQFPDYRLRLLSKPIKIINKKTKKIIYDMFDTMYANNGIGLAAPQINILKQIIVISSLKPTMSELVLINPVILKKNKKYINTIEGCLSIPKKTAKIKRSSCIKIQAINTYGKSFTLTAKSLLSICIQHEIDHLIGKLFIDYIN
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: MURC_BACC4
Sequence: MTVYHFVGIKGTGMSSLAQILHDMKHTVQGSDYEKRFFTQTALEKRSISILPFDKNNVEEGQVIIAGNAFPDTHEEIVAAKELNIPVHRYHHFLGDLMSQYTSVAVTGAHGKTSTTGLLAHVMQGAHPTSYLIGDGTGHGVENSKYFVFEACEYRRHFLSYNPDYAIMTNIDFDHPDYFADINDVFSAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGTIFDVFVRNTYYDTFKITGYGNHSVLNALAVIALCHYENVDVEAVKHQLTTFEGVKRRFNEKPMGEQVIIDDYAHHPTEINATIEAARQKHPEREIVAVFQPHTFSRTEKFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDVLKKHKNGVLIFMGAGDIQKFEAAYVKEVQVAEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNQ_ECOLI
Sequence: MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGPLRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGNPQVLIKNPPSQRLQEFLQHVS
What is the function of this protein?
Part of the binding-protein-dependent transport system for glutamine.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Glutamine transport ATP-binding protein GlnQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UPPP1_PSET1
Sequence: MSIIEIIVLALIQGFTEFLPISSSAHLILPSQILGWEDQGLAFDVAVHVGTLIAVVIYFRKEVSSILSAWFKSFGAQGSTDDSKLGWWIILGTIPAAILGLLLKDMIELYLRSAWVIAVTTIIFGLLLWYADAKGKQIKTIYQLNWKTALIIGLAQAVAMIPGTSRSGITMTAGLMLGMNKQSAARFSFLLAIPIISMMGLYYTVELALGDHLVDWSTLLLGVVLSFLSAYVCIYMFLKVIERMGMLPFVIYRLLLGVGLIVFLTL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 1, Bacitracin resistance protein 1, Undecaprenyl pyrophosphate phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENGB_GEODF
Sequence: MLIKYVEFIKSATRAAHYPPGDLPEIAFAGRSNVGKSSLINVLVNRKSLVRTSSTPGRTQLINFFDVNGQFTLVDLPGYGFAKVPLAVKKQWGPMMENYLAKRANLRGVILILDIRRTPVAEDIQMLHWLQAYSIKPILVITKCDKVSKNERGKQSRIIAQTLGVETEELNFFSALNREGKDLIWRRIEEVLPAETAGSAGEAPKAT
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: IMEP_STRNI
Sequence: MVRKRALGLAGSALTLVLGAVGFTAPAQAAPSCPAGSLCTYSGTGLSGARTVIPASDMEKAGTDGVKLPASARSFANGTHFTLRYGPARKVTCVRFPCYQYATVGKVAPGAQLRSLPSPGATVTVGQDLGD
What is the function of this protein?
Inhibits microbial metallo-proteinases, such as thermolysin, but not serine, thiol, or carboxyl proteinases.
What are the official names of this protein?
Metalloproteinase inhibitor.
Protein: PO13_NASVI
Sequence: VDAFADDLLLLVQGNRRNELEQSASEALSVVYRYGTNIGVEVSDSKTVCMMLKGSLNMLNRVVHVSTNGMDDKRIRCVDRVRYLGVNVGIGMDFSVHIDGMKRRLTTAIMRLRGVLRKSWGLKRGVVSMVVKGLFLPAVMYGASVWYEQLHKRKLRGSRRLSEELVSCQRVVLYACTRVCRTVSTEAMQILFGSLPWDIECFRRANCTKSKGPAMNESDLVTDEDLYELSLHECRELVDQRALAAWQDRWEATSNGRVTYEWIRDVGFSGRSMKYFGAEPEGLLRLTGHGSMNSFLFSRNLSNSPACACGTEREDWIHVLCECDMYAAFRDLDSIGVRRTEVGWDVSGVLLDRASMSVCVPLSSCAFRMRELIVQRMRENEES
What are the official names of this protein?
Retrovirus-related Pol polyprotein from type-1 retrotransposable element R1 3, Retrovirus-related Pol polyprotein from type I retrotransposable element R1 3.
Protein: ATAT_CULQU
Sequence: MEFRFNCHPLFRQRIVRINNSLLPTGFTAPCRRTALDATAQISEIINFIGQLSAQAQGLSNPVTTSQKLRNSDHHIYLMFEPNEKHGLVVGILKVGHKSLYVFDQNGETVNVTAPCVLDFYVHESRQRGGLGRELFEHMLNEEKIQPQSLAIDRPSGKLLGFLQKHYGLYNKIPQMNNFVVYEGFFSSKQNGSDIDGRRMHITASTSSSTNNHHAPPSASTNNNEYENNHATSHDLEEPAAPQEESPQDNEDVPEEVLSANLQNLNMADASDYVDYHHHHQLQHAKSGHEVTFADDYGEIPEPTADPDPYTFHPHHLELQNQQEQQKQMMINRENSASPQSISQQHTPEHPGPRKPIRYTKQHTGLKNMSSGVGAAVTPSAKMEFDQEENEGFGSVKINRPIGKSNTRNSLHSGDDNESVHSKGSDSSHMTEHGHFDLKFYHNKLW
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase, Alpha-TAT, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
Protein: RL17_SHIB3
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: VPC15_MYCTU
Sequence: MIVDTSVWIAYLSTSESLASRWLADRIAADSTVIVPEVVMMELLIGKTDEDTAALRRRLLQRFAIEPLAPVRDAEDAAAIHRRCRRGGDTVRSLIDCQVAAMALRIGVAVAHRDRDYEAIRTHCGLRTEPLF
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Degrades total E. coli RNA, which is partially inhibited by cognate antitoxin VapB15 (PubMed:25450593).  Upon expression in M. smegmatis inhibits colony formation, which is neutralized by coexpression with VapB15 (PubMed:20011113).
What are the official names of this protein?
Ribonuclease VapC15, RNase VapC15, Toxin VapC15.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: YQZE_BACSU
Sequence: MKTNDYVKYMTQQFVKYIDTPRDERKERKEVRKETKTPVSQQWFGILPYGFRLWLKRKK
What are the official names of this protein?
Uncharacterized protein YqzE.
Protein: PSBT_SPIMX
Sequence: MEALVYTFLLVGTLGIIFFAIFFREPPKLPEASKSKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NTPP_RICPU
Sequence: MKQNRKNLPIILASSSPARIELLNRIKIIPSQIIPADIDETPNLRELPAPLAIRLAYEKAIKIASQIEESAIIIAADTVAAVGRRILPKATTYEEVKNCIKMLSGRRHRVYTGLCIIKKENDQLTVRQKIVQTIVKFKKLSDEEINFYCSLDEGIDKAGGCKISGYAEAFISFISGSYSNVMGLPLFETVNALTSLGFRCSSIMPAKMNYCHSAT
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_LACDA
Sequence: MELLEERIKKDGVVLPGNVLKVNSFLNHQIDPQLMMTLGQEFARLFKDAGVTRVLTAEASGIAPGIMAAYCLGVPMVFARKKKPSTVTDAVYTAEVFSYTKQVTNTISVEAKFLDANDRILVIDDFLANGEAAKGLISLAEQAGAEVVGVGVVVEKAFQGGHDWLVNHGYHLEALASIKEFADGQVIFN
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOPA_SALT1
Sequence: MKISSGAINFSTIPNQVKKLITSIREHTKNGLTSKITSVKNTHTSLNEKFKTGKDSPIEFALPQKIKDFFQPKDKNTLNKTLITVKNIKDTNNAGKKNISAEDVSKMNAAFMRKHIANQTCDYNYRMTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLSLQATSSPSSPADWAKKLTDAVLRQKAGETLTAADRDFSNADFRNITFSKILPPSFMERDGDIIKGFNFSNSKFTYSDISHLHFDECRFTYSTLSDVVCSNTKFSNSDMNEVFLQYSITTQQQPSFIDTTLKNTLIRHKANLSGVILNEPDNSSPPSVSGGGNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTIDSLPDKYSQEKVQAMEDLVKSLRGGRLTEACIRPVESSLVSVLAHPPYTQSALISEWLGPVQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMTGVDCTDGTRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSDTAMMLSTDTLLTMLNPTPDTAWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQATQRRFGELIDIILSTEEHGELNQQFLAATNQKHSTVKLIDDASVSRLATIFDPLLPEGKLSPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALMQKAWELSPAIFPSSEQFTEWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLAWA
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway.  For instance, prevents host innate immune response by ubiquitinating and thus sending to degradation host E3 ubiquitin ligases TRIM56 and TRIM65.
What are the official names of this protein?
E3 ubiquitin-protein ligase SopA, HECT-type E3 ubiquitin transferase SopA, Salmonella outer protein A, Secreted effector protein SopA.
What is the protein family that this protein belongs to?
Belongs to the SopA E3 ligase family.
What are the subcellular locations of this protein?
Secreted. Host cell. Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cell.
Protein: EXBD_SYNY3
Sequence: MASSPKAPKSHRKFQSIYHPTRPLSLWQDNQHDQGEVRIEIIPLIDVVFCILTFFILGAVGLSRQQAISLDLPRASTGAPQMREMFMVSLDDLGQLYVEKQPVSQEQMVSALQNYHQYNPSGLIVLHASRNASYNDVVQLLDTLRTVGGDRVALATLPGDGQTPSGMNPNSFNNPNLGLPGMTPGNAFPNGANPGMSNFNNSNPGGSGAGVPNFSNTPLPGMPDANGNVSPNPGMNPGFPGGGAMSPDPNSQSPNLPGMGNTVPSAPQQ
What are the official names of this protein?
Putative biopolymer transport protein ExbD.
What is the protein family that this protein belongs to?
Belongs to the ExbD/TolR family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: NHAA_ERWT9
Sequence: MNLFLKKLLKNDATGGVVLIVAAAFAMFLANNDSTRHAYQAMLTLPVQFRFGALDINKDLLLWINDALMALFFLMIGLEVKRELMMGSLKGRERAMFPLIAALGGMLAPGLIYAAFNHQDAQAIHGWAIPTATDIAFALGILALLGSRVPAALKMFLMALAVIDDLGAIVIIALFYTSELSLISLTVAAASIAVLAVLNGCGVRKTSVYLAVGMVLWVAVLKSGVHATLAGVIVGLFIPLKKQEGHSPAIELAHGLHPWVSWLILPLFAFANAGISLSGVSLNGLFSAVPLGITLGLFIGKPLGITLICWLAVKLKIAALPENTRLIDIAAVGVLCGIGFTMSIFIASLAFDGAHEELVTLAKLGILSGSVISALVGYTLLRVKLR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATN1_SCHOC
Sequence: MTPSIGYVDEDENGQKSKFLRSSDDPYRLSIEEVIEKFETHLENGLSDEQAKSKLAKVGLNNLGADEKISISKILAHQIFNAMVLVLIISLIIALAIKDWISGGVIGFVVFINIFVGFIQELKAEKTMGSLRSLSSPMARALRNGVDSNINAEEVVPGDIIHIKVGDTIPADLRLVDCMNLETDEALLTGESLPVAKDHEEIYDYGAPIPVGDRLNMAFSSSIVAKGRGTGIVVATGLDTEIGKIAKSLKNNDDAVVVKVDKSLNPSTKDYLIAVIKTTKNIIFNVLGTNVGTPLQRKLSWLAILLFWVAVLFAIVVMASQEMRVNRNVAIYAICVALSMIPSSLVVVLTITMAIGAQVMVTKNVIVRKLDSLEALGGINDICSDKTGTLTMGKMIARKVWIPNVGSYLVQNSNEPFNPTVGDISFNENSPKFIKETDDELDFIPHLPSPTPILFEKWLHIATLANIASLNQIQNEMDGSIEWEAHGDATEIAINVFTTRLGYTRDKLIGDSLEHLNEFPFDSSIKRMSTVYKDKDGNSTVYTKGAVERVLSCCKYWYNPELTALSEEDKLLIESNMNALSSEGLRVLAFAQREINISKENVSNREVVESNLIFLGLIGIYDPPRPESAKSVKLCHKAGINVHMLTGDHPGTAKAIAQEVGILPHNLYHYREEVVKVMVMIANEFDSLSDDEIDNLPVLPLVIARCAPQTKVRMIEALHRRGKFVAMTGDGVNDSPSLKKADVGIAMGLNGSDVAKDASDIVLTDDNFASILNAIEEGRRMSSNIQKFVLQLLAENVAQALYLMIGLAFIDKSGYSVFPLSPVEVLWIIVVTSCFPAMGLGQEKASHDILEQPPNATIFTWEVIIDMIAYGFWMAVCCLVCFVCIVYGKGDGSLGENCNEGSDTGCNLVFRGRSGAFAAFTWCALLLAWECIHLRLSFFKMRPELENPWWKQLAIDLWDNQFLFWSVMGAIVSVFPVVYIPVINNKVFLHAPIGYEWGLAVAFTILFLIGAEGWKWFKRVYYRKSNANNPEYDLERNDPFKEYSSFSKSNTMEIV
What is the function of this protein?
Catalyzes the hydrolysis of ATP coupled with the export of sodium and potassium from the cell (PubMed:9430707).  May be an inefficient potassium exporter (PubMed:9430707).  May transport other cations such as lithium (By similarity).  Sodium/potassium efflux ATPases are involved in salt tolerance and maintaining the membrane potential across the plasma membrane in high salinity (Na+) or alkaline (K+) environments (PubMed:9430707).
What are the official names of this protein?
Sodium/potassium exporting P-type ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.
Protein: PTKB_ECOLI
Sequence: MKRKIIVACGGAVATSTMAAEEIKELCQNHNIPVELIQCRVNEIETYMDGVHLICTTAKVDRSFGDIPLVHGMPFISGIGIEALQNKILTILQG
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.  The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport.  It can also use D-glucitol.
What are the official names of this protein?
PTS system galactitol-specific EIIB component, EIIB-Gat, Galactitol-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_NEIMB
Sequence: MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKGLFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMPEGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLDNGEYDAIILAAAGLQRLKLDGRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGGSCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGARELIGAVLNTEN
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: MRNC_ENTFA
Sequence: MRDYKQLNGLALAYVGDAIYEIYIRDYLVSLGQTKPNVLHRMATHYVSAKAQASLMQAMLAGEMLTEEEEVMYKRGRNAKSHTFAKNADVTTYRVATGFESLMGYLHLTQQKERLEELINWCIKKVGETNEK
What is the function of this protein?
Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor.  Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.
What are the official names of this protein?
Mini-ribonuclease 3, Mini-3, Mini-RNase 3, Mini-RNase III, Mini-III.
What is the protein family that this protein belongs to?
Belongs to the MrnC RNase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4CA_SINFN
Sequence: MRLHHLGPDFPEALVDELLEGNVVFLCGAGVSAPQLPNFRDLVLNVYNRLGEERTPAEDHAFQASRYEEVLGALSRRLVRSEDVIDAAAAELQVPANPDTAHHDVILRLSRDQVGRPIIVTTNFDTLFERSLMVSHSAAFATQESAAGQDIPAPGSARFTGVVHTHGRLTDDELNLSQTELVLTSAQYGEAYLRAGWAARFLFDLMRCRTLVLVGYTANDAPVRYILNVLEGDRERFTDLRRVYALSSSNGDPQAAAAPWQALAVEPLLFDPEGGNPYGPLWSSLEGLANLVENPDVRRREMIAAIVSGPVSETTDHDIRTLKWALGARADLFEHFITRCEDAAWFDTLAVVIRAFGERARAWMLARWFARGWDDKVRYLTAIKHLGRGSQEFSDAVFRELDQNRPQDAIWEKAWRLLAEAAAAASHDSLRDYQLRHRLNRGPVVESDLGHLVNAIGPRLTIEAPFRDEDPSEHPNQLSDIARFSMESEHQEFLRDVLASPAGNAENILRLLERGSQRLSCQLRTARDAELIGQVRDVTDFGVPSVVNHQQNQHRRGFVPLTVFITSALPMAAQANLEGTKRVVGGWRAEPFNLTTRLWMHALTHQALFTADEAIEALATSNEAAFWSFALEFVAIVRARIAQASGEAVERLVRRLLVEGPQRYADREQNADGIDWQDRARDRDIWVRLTAISEHVVLPQEAETLLHEIRERRTYLSREIDERDLFRTWSSGVRAVRGRTAQIVSAQPSERLTIADRLEESSDIEDREGWVEYCREDPVGAYAALRSHPLEIGVVARWATWLEIIPSRANMTSPEWLRVIQEAVELLGEADDEIVIALVGPLARIAEHSRQLQLALPANWWDRLWQAAEGEPDVDWGDDVETYDRVINSTGGSLAEALLQAISSQRENGDDVNAADFQRLQRMIVSMTYSGEMARAACVRYLSFVFSVSNEIALDHLRPFIAADNDEGRRLRGVLVEYNSFVADTEISFADLILQGVRESRQKDVSAANAASHLVRAVVASFDEPNVVRGISPQQARQTLREAAADIRVGALKIMTNWLEENPDDERAAAWTDLYGPTFQAIWPRDRSYLSNDVSKEVFSLATAAGTAFEAAVEALLPYVSTFEDDWLSLHDLERNNAELATRFPVAALRLVWAACGPPCKGRTSDIAAILDAVAAANPALAVDRRMHKLRLLAVSH
What are the official names of this protein?
Uncharacterized protein y4cA.
Protein: DIR_SINHE
Sequence: MGGEKAFSFIFLLFLCFFLANLSASSAHPPRQKLKQRIPCKQLVLYFHDVVYNGHNKANATASIVGAPQGADLVKLAGENHFGNVVVFDDPITLDNNFHSPPVGRAQGLYVYDKKDTFHSWLSFSFTLNTTMHQGTLIFMGADPILIKNRDITVVGGTGDFFMARGIATIATDSYEGEVYFRLKVDIKLYECW
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism (By similarity).  Also involved in the biosynthesis of etoposide, a chemotherapeutic compound of the topoisomerase inhibitor family (PubMed:26359402).
What are the official names of this protein?
Dirigent protein, PhDPO.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: HIS7_ALKCK
Sequence: MARSYELTRTTGETDISLRLNLDGEGKADIETGVPFMEHMLDLFAKHGQFDLFVKASGDIEVDAHHTTEDLGICIGQAVKEALGTKEGIKRYGNAFVPMDETLAQVVVDLSNRPHLEFRADFPSQKVGTFDTELVHEFFWKLALEARMNLHIIVHYGHNTHHIIEAIFKACARALDEATAIDPRIKGILSTKGLL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COF_SALTY
Sequence: MARLAAFDMDGTLLMPDHHLGRETIATLARLRERDITLTFATGRHVLEMRHILGTLSLDAYLITGNGTRIHSLEGDVLHRQDLDPQVADTVMHHAWDTRASMHVFNDNGWFTGQEIPALLQAHVYSGFRYQVIDIKSIPAHQVTKICFCGDHDDLIRLRIQLNEALEERAHLCFSAVDCLEVLPLGCNKGSALAVLSNHLGLSLADCMAFGDAMNDREMLGSVGRGLIMGNAMPQLIAALPHLSVIGHCGNQAVSHFLTHWLDNPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: ARLY_STRSV
Sequence: MVNHKLWGGRFEASLEDWVEEFGASIGFDYRLAPYDLQGSLAHVKMLGQTGIIAPEEAAAIQAGLEKLLVRYQAGELEFDVRNEDIHMNMEALLTEEIGPVAGKLHTARSRNDQVATDMHLYLKDQIGQIADKLLNLRQVLLNLAEEHVETIMPGYTHLQHAQPISFAHHLLAYYQMFSRDSQRFAFNLEHTNLSPLGAAALAGTTFSIDRELTADLLGFKGIYHNSLDAVSDRDFILEFLSNSSILIMHLSRLCEELINWCSYEYGFVSLSDTFSTGSSIMPQKKNPDMAELIRGKSGRVYGHLFSLLTVMKSLPLAYNKDLQEDKEGMFDTVDTIQKSLDIMAGMLSSMTVNKEKMLVSTQQDFSNATELADYLAKKGLPFREAHEIVGKLVLECSKAGYYLQDIPLSRYQEVSSLIEEDIYQALESQTAVQKRNSLGGTGFAQIRQELERAKRQLEK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKAP2_RAT
Sequence: MPNPGSTSSPGSIPEEIRNLLADVETFVADTLKGENLSKKAKEKRDSLIKKIKDVKSVYPQEFQDKGDAEEGDEYDDPFAGPPDTISLASERYDKDDDGPSDGNQFPPIAAQDLSFVIKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIEGYDVRMNNTLRKDAKKDCCFEICAPDKRIYQFTAASPKDAEEWVQQLKFILQDMGSDVIPEDEDEKGDLYDDVDHPVPVSSPQRSQPIDDEIYEELPEEEEDTASVKMDEQGKGSRDSVQHPSGDKSTDYANFYQGLWDCTGSLSDELSFKRGDVIYILSKEYNRYGWWVGEMQGAIGLVPKAYLMEMYDI
What is the function of this protein?
May be involved in B-cell and macrophage adhesion processes.  In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation.  May play a role in src signaling pathway (By similarity).
What are the official names of this protein?
Src kinase-associated phosphoprotein 2, SKAP55 homolog, SKAP-55HOM, SKAP-HOM, SKAP55-HOM, Src family-associated phosphoprotein 2, Src kinase-associated phosphoprotein 55-related protein.
What is the protein family that this protein belongs to?
Belongs to the SKAP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI_YERPY
Sequence: MRKQSLVTLLMVLLSLVWLPASAERIRDLVTVQGVRDNALIGYGLVVGLDGSGDQTMQTPFTTQSLSNMLSQLGITVPPGTNMQLKNVAAVMVTAKLPAFSRAGQTIDVVVSSMGNAKSIRGGTLLMTPLKGVDNQVYALAQGNVLVGGAGAAAGGSSVQVNQLAGGRISNGATIERELPTTFGTDGIINLQLNSEDFTLAQQVSDAINRQRGFGSATAIDARTIQVLVPRGGSSQVRFLADIQNIPINVDPGDAKVIINSRTGSVVMNRNVVLDSCAVAQGNLSVVVDKQNIVSQPDTPFGGGQTVVTPNTQISVQQQGGVLQRVNASPNLNNVVRALNSLGATPIDLMSILQAMESAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: Y1708_MYCTO
Sequence: MPAGLPGQASVAVRLSCDVPPDARHHEPRPGMTDHPDTGNGIGLTGRPPRAIPDPAPRSSHGPAKVIAMCNQKGGVGKTTSTINLGAALGEYGRRVLLVDMDPQGALSAGLGVPHYELDKTIHNVLVEPRVSIDDVLIHSRVKNMDLVPSNIDLSAAEIQLVNEVGREQTLARALYPVLDRYDYVLIDCQPSLGLLTVNGLACTDGVIIPTECEFFSLRGLALLTDTVDKVRDRLNPKLDISGILITRYDPRTVNSREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSAGALAYRALARELIDRFGM
What is the function of this protein?
May play a role in septum formation.
What are the official names of this protein?
Uncharacterized protein MT1749.
What is the protein family that this protein belongs to?
Belongs to the ParA family.