PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_JANSC
Sequence: MSLFTLFLLALVQGITEFLPISSSGHLILLPNLLGIEDQGQAIDVAVHVGTLGAVILYFWRDVKAAIAGTPRLLTGRIDTPGAKLAFLLIIATIPVIIFGLFLEVTGIYDSLRSIAVIGWTMLIFGLVLYWADQRGGTEKQSDDWSLRDAVTMGLWQAVALIPGTSRSGITITAARFLGYDRESAARVAMLMSIPTIIATGVFAGAEVIATADAQTARDGAIAAALSFLAALAALTLMFRLLKSVSFTPYVIYRVILGVILLVIAYA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIS_ECOLI
Sequence: MQILFNDQAMQCAAGQTVHELLEQLDQRQAGAALAINQQIVPREQWAQHIVQDGDQILLFQVIAGG
What is the function of this protein?
Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.
What are the official names of this protein?
Sulfur carrier protein ThiS, Thiamine biosynthesis protein ThiS.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein ThiS family.
Protein: AI2M_YEAST
Sequence: MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFCAPFRLIYHCIEVLIDKHISVYSINENFTVSFWFWLLVVTYMVFRYVNHMAYPVGANSTGTMACHKSAGVKQPAQGKNCPMARLTNSCKECLGFSLTPSHLGIVIHAYVLEEEVHELTKNESLALSKSWHLEGCTSSNGKLRNTGLSERGNPGDNGVFMVPKFNLNKVRYFSTLSKLNARKEDSLAYLTKINTTDFSELNKLMENNHNKTETINTRILKLMSDIRMLLIAYNKIKSKKGNMSKGSNNITLDGINISYLNKLSKDINTNMFKFSPVRRVEIPKTSGGFRPLSVGNPREKIVQESMRMMLEIIYNNSFSYYSHGFRPNLSCLTAIIQCKNYMQYCNWFIKVDLNKCFDTIPHNMLINVLNERIKDKGFMDLLYKLLRAGYVDKNNNYHNTTLGIPQGSVVSPILCNIFLDKLDKYLENKFENEFNTGNMSNRGRNPIYNSLSSKIYRCKLLSEKLKLIRLRDHYQRNMGSDKSFKRAYFVRYADDIIIGVMGSHNDCKNILNDINNFLKENLGMSINMDKSVIKHSKEGVSFLGYDVKVTPWEKRPYRMIKKGDNFIRVRHHTSLVVNAPIRSIVMKLNKHGYCSHGILGKPRGVGRLIHEEMKTILMHYLAVGRGIMNYYRLATNFTTLRGRITYILFYSCCLTLARKFKLNTVKKVILKFGKVLVDPHSKVSFSIDDFKIRHKMNMTDSNYTPDEILDRYKYMLPRSLSLFSGICQICGSKHDLEVHHVRTLNNAANKIKDDYLLGRMIKMNRKQITICKTCHFKVHQGKYNGPGL
What are the official names of this protein?
Putative COX1/OXI3 intron 2 protein.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RBP10_DANRE
Sequence: MAELGAGSLLTGDPAFNYQEHELNERLKRLYPAVNEEETPLPRSWSPKDKYSYIGLSQNNLRVHYKGHGKNHKDAASVRATHPIPAACGIYYFEVKIVSKGRDGYMGIGLSAQGVNMNRLPGWDKHSYGYHGDDGHSFCSSGTGQPYGPTFTTGDVIGCCVNLINNTCFYTKNGHSLGVAFTDLPPNLYPTVGLQTPGEIVDANFGQQPFVFDIEDYMSEWRAKIHSMIARFPIGERLGDWQAVLQNMVSSYLVHHGYCATAMAFARATETMIQEDQTSIKNRQRIQKLVLAGRVGEAIDATQQLYPGLLEHNPNLLFMLKCRQFVEMVNGTDSEVRCFSVRSPKSQDSYPGSPNMSPRHGATNPHLHSTGADSPTCSNGVTPPNKNKSHNKYTGISSASSSPSSSPSSVNYSESNSTDSTKSQPHSATSNQETSDSEMEIEAEHYSNGVTESSTRIMNGTYKHQEILQADDNSVDDTCSSRQLCGGNQAATERMIQFGRELQTLSEQLCRQYGKNATHKKMLQDAFSLLAYSDPWNCPVGQQLDPMQREAICSALNSAILESQNLPKQPPLMLALGQATECVQLMARVRSGSCSFARVDNFLH
What is the function of this protein?
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways.
What are the official names of this protein?
Ran-binding protein 10, RanBP10.
What is the protein family that this protein belongs to?
Belongs to the RANBP9/10 family.
Protein: ATPF_ARATH
Sequence: MKNLTDSFVYLGHWPSAGSFGFNTDILATNPINLSVVFGVLIFFGKGVLNDLLDNRKQRILNTIRNSEELREGAIQQLENARARLRNVETEADKFRVNGYSEIEREKLNLINSTYKTLKQLENYKNETILFEQQRTINQVRERVFQQALQGAIGTLNSCLSNELHLRTINANIGMFGTMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MDTJ_YERPS
Sequence: MIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHVVMYFMITGSYVMLSLAVKKVALGVAYALWEGIGILIITIFSVMWFGETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNRHRGNRPPSVQGLKTQTTGHHKGVAVESGEHHAAA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RISB_BURCJ
Sequence: MEIGQYQPNLEGDGLRIGIVQSRFNEPVCNGLADACVEELERLGVTGEDVLLVSVPGALEIPLALQKLAESGQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFNLPIANAVLTTENDEQAVARMTEKGRDAARVAVEMANLTMALDQLGDDEDEEEDEDDEEERA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: BTG1_BOVIN
Sequence: MHPFYSRAATMIGEIAAAVSFISKFLRTKGLTSERQLQTFSQSLQELLAEHYKHHWFPEKPCKGSGYRCIRINHKMDPLIGQAAQRIGLSSQELFRLLPSELTLWVDPYEVSYRIGEDGSICVLYEASPAGGSTQNSTNVQMVDSRISCKEELLLGRTSPSKNYNMMTVSG
What is the function of this protein?
Anti-proliferative protein.
What are the official names of this protein?
Protein BTG1, B-cell translocation gene 1 protein, Myocardial vascular inhibition factor, VIF.
What is the protein family that this protein belongs to?
Belongs to the BTG family.
Protein: LEPA_FLAPJ
Sequence: MKHIRNFCIIAHIDHGKSTLADRLLGATQTVTAREEKAQLLDNMDLERERGITIKSHAIQMEYTYQGQEYILNLIDTPGHVDFSYEVSRSIAACEGALLIVDAAQSIQAQTISNLYLALENDLEIIPVLNKVDLPSANPEEVSDDIIDLLGCKLEDIIHASGKTGFGVENILAAIIEKIPHPKGNIEEPLQALIFDSHYNPFRGIEVIFRVKNGQIKKGQKIKFMATGNEYFADEIGTLKLNQVPKNVISAGDVGYLISGIKEAKEVKVGDTLTDAKTPTTNMIVGFEDVKPMVFAGIYPVDTDDYEELRNSMEKLQLNDASLVFAAESSAALGFGFRCGFLGMLHMEIIQERLEREFNMTVITTVPNVSYLAYTKKEPEVGMIVNNPTDLPEPSKLDRVEEPYIKATIITKADFVGNVMGLCIEKRGVITNQTYLTTERVELNFDMPLAEIVFDFYDRLKTVSKGYASFDYSPIGMRTSKLVKLDVLLNATSVDALSALIHESNAYHIGKKMCEKLKELIPRQQFDIPIQAAIGAKIIARETIKALRKDVTAKCYGGDISRKRKLLEKQKKGKKRMRLVGNVEIPQEAFMAVLKLND
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DEAR_HUMAN
Sequence: MTMFKGSNEMKSRWNWGSITCIICFTCVGSQLSMSSSKASNFSGPLQLYQRELEIFIVLTDVPNYRLIKENSHLHTTIVDQGRTV
What is the function of this protein?
Dual endothelin-1/angiotensin-2 receptor that is functionally coupled to a calcium-mobilizing transduction system, responding equivalently to both endothelin-1/EDN1 and angiotensin-2 peptides in a highly specific manner (PubMed:17446437, PubMed:24465725).  Also binds the signal peptide of VEGFA (PubMed:17446437, PubMed:24465725).  May play a role in angiogenesis with a significant role in cardiovascular and neural development (By similarity).
What are the official names of this protein?
Dual endothelin-1/angiotensin II receptor, Dear, Dual endothelin-1/VEGFsp receptor, DEspR protein, FBXW7 antisense RNA 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ARRD3_RAT
Sequence: MVLGKVKSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAGSNTAYTQNYTEEVEYFNHKDILIGHERDDDNCEEGFSTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPSLLSPQAGTKEKTLCCWFCTSGPISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKGKMKEVKQLVANLRGESLSSGKTETWDGKLLKIPPVSPSILDCSIIRVEYSLMVYVDIPGAMDLLLSLPLVIGTIPLHPFGSRTSSVSSQCSMNMNWLGLSLPERPEAPPSYAEVVTEEQRRNNLAPVSACDDFERALQGPLFAYIQEFRFLPPPLYSEIDPNPDQSSEDRPSCPSR
What is the function of this protein?
Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors.  Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation.  May recruit NEDD4 to ADRB2.  Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.
What are the official names of this protein?
Arrestin domain-containing protein 3, Liver regeneration-related protein LRRG00048.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome. Endosome. Early endosome. Note=Associated with plasma membrane, as well as with endosomes and lysosomes during endocytosis.
Protein: SURE_PARUW
Sequence: MSSKPLILVTNDDGVHAKGIRHLWQSIQDLADLIIVAPQQEQSAVSLSITVRRPLHIEKVDWLNAQADVWSVNGTPADCVKLALNVVLPKRPQLIVSGINRGTNAGRNIFYSGTVAAIMEGVMQGIPGIAFSYGDYFNPSYHLIESFIPGIVNYALQNAMQEGTFLNVNFPKTEHGPIKGIRLTTQGKEYWAENPEKRQHPAEQNSYYWLGSKLAEYDEREDSDIFLLRKGFATVVPLHIGDLTNHSHLLKEKLAFETFVN
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_SHEAM
Sequence: MTEHIQDENKLIAERRAKLEHVRKNCPANGHPNTFRRKHKAAELQAQFGDKTKEELEALGFQTAIAGRVMAKRGPFLVLQDVSGRIQAYADKGVQADLKDRYAGLDIGDIIGVEGTLHLSGKGDLYVNMERYELLTKALRPLPEKFHGLTDQETRYRQRYVDLIVNEDSREAFKMRSKVVAAIRNFMIKKEFMEVETPMMHVIPGGASARPFVTHHNALDIEMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLIDLTEEMLSSIAKELLGDTKLPYGEHVIDFGGPYTRMSMLEAIKHYNPDNATIQAMTYEEVKNIDFMRKLAKDVGIETETFWSCGQLLEEIFGETAEPKLMQPTFITGYPADISPLARRSDGNDFITDRFEFFIGGREVANGFSELNDAEDQDNRFKAQVEAKDAGDDEAMFYDADFITALEHGLPPTAGQGIGIDRLVMLFTNTHTIRDVILFPAMRPQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_STRA5
Sequence: MSKTIAINAGSSSLKWQLYEMPEEKVVAKGIIERIGLKDSISTVKFDDKKDEQILDIVDHTQAVKILLEDLTKHGIIKDFNEITGVGHRVVAGGEYFKESALVDDKVVEQVEELSALAPLHNPAAAAGIRAFREILPDITSVCVFDTAFHTTMQPHTYLYPIPQKYYTDYKVRKYGAHGTSHQYVAQEAAKQLGRPLEELKLITAHVGNGVSITANYHGQSIDTSMGFTPLAGPMMGTRSGDIDPAIIPYLVANDPELEDAAAVVNMLNKQSGLLGVSGTSSDMRDIEAGLQSKDPNAVLAYNVFIDRIKKFIGQYLAVLNGADAIIFTAGMGENAPLMRQDVIAGLSWFGIELDPEKNVFGYFGDITKPDSKVKVLVIPTDEELMIARDVERLKAK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUMD_ECO57
Sequence: MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
What is the function of this protein?
In vitro catalyzes the addition of water to fumarate, forming malate.  Cannot catalyze the reverse reaction.  Cannot use the cis-isomer maleate as substrate.
What are the official names of this protein?
Fumarase D.
What is the protein family that this protein belongs to?
Belongs to the FumD family.
Protein: GYRA_STAAS
Sequence: MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGKIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTENGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGDDQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDIQQSSDEE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_QUEPE
Sequence: MEEFQGYLELDIFRQHDFLYPLIFREYSYALGHGHGLNRYMLLENIGYDNKSSLLIVKRLITTMYQQNYLIISANDSKQNPFFGYNKNLHSKILSEGFAIIVEIPFYLRLISSLEGAEIVRFYNLRSIHSIFPFLEEKFPHLNYSADILIPYPAHLEILVQTLRYRVKDASYLHLLRFFLHEYSNCNSLIITNKSISIFSKSNPRFFLFLYNSYICEYESIFLFLRNQSSHLRLTSSGVLFERLCLYRKIEHFAEVFANDFPVIPCFLKDPFMHYVRYQGKSILASKDTPLLMNKWKSYLVNLWQCHFDVWSHAASIRINQLSKHSLDFLSYFSSVRRNPAVVRNQMLENSFLLNNAPNKLDTIVPIIPLIGSLAKAKFCNAVGHPISKLTRADLSDFEIINRFLHICRNLSHYYSGSSKKKNMYRIKYILRLSCVKTLARKHKSTARAFLKRVDSEFFQEFFTEEGGFISLIFPRASFALRRLYSGRVWYLDIIFINGLSNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GPMI_SACD2
Sequence: MSEVKKPLALIILDGFGYSESDKYNAINAAKAPTWRKIWAENPKTTIATSGMAVGLPEGQMGNSEVGHMTLGAGRVVYQNFTRINKAIADGDFYTNPVYTKAVDDAQSQGKAVHVIGLLSDGGVHSHEDHMIAMMELAVKRGAEKVYMHAFLDGRDTPPRSAKAPLQKTEEKLKALGGGKIASIIGRFFALDRDNRWDRVQQAFDLMVDGKAAFTAQSATAGLEAAYERDENDEFVKATAIVDADGKPVTIEDGDAVIFMNFRPDRARQLTNAFVDKNFDGFARARVPALSDFVMTTEYSADIDTSCAYPPEDLVNSFGEVMAKNGKKQLRIAETEKYAHVTFFFSGGQESLYEGEDRILVPSPQVETYDEQPEMSAPEVTAKLVDAIENGGYDAIICNYANCDQVGHTGDFDASVKAVEAVDAALAEVFAALERVGGEALITADHGNVELMYDDEAQQLHTQHTTLPVPLVYVGKRDISLEQGGSLADIAPTMLALLDVPQPTEMNGRNLVKFSK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: YGGE_SHIFL
Sequence: MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDIATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDGKSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKAAIDNAIHQAQELANGFHRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQAAIQFDDQVDVVFQLEPVDQQPAKTPAAQ
What are the official names of this protein?
Uncharacterized protein YggE.
Protein: EFG_FRAT1
Sequence: MPRNTALEKYRNIGICAHVDAGKTTTTERILFYTGLSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWSGMDQQFEKHRINIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWRQANKYGVPRIVFVNKMDRSGADFERVCAQIKTRLKANVVPVQLNIGAEEDFKGVIDLIRMKAIMWNEEDMGLTYELVDIPADLQDRAEELRMEMIEAAAEASEELMEKYLEGGELSEDEIHQGLRARVLNNEIVLAFCGSAFKNKGVQAVLDGVVRYLPAPNQVPAIKCETEDGEPASRPSSDDAPFAALAFKLATDPFVGNLTFIRVYSGVLKSGDAVYNPVKGKKERVGRIVQMHANKRDEIKEVRAGDIAACIGLKDVTTGDTLCDQEDVVILEKMDFPEPVISVAVEPKSKADQEKMSIALGKLAAEDPSFRVKTDEESGQTIISGMGELHLDIVVDRMRREFKVEANVGNPQVAYRETIRSKVEQEAKFVRQSGGRGQYGHVFVRFEPLDEVDENGEAKVFKFVDEVVGGVVPKEYIGSVAKGIEEQLNNGVLAGYPMIGVKATLYDGSYHDVDSSEMAFKIAGSMALKEGAKKANACILEPIMKVEVVTPEDYLGDVMGDLNRRRGIIEGMDENPSGRVINALVPLAEMFGYATNVRSISQGRASFSMEFKKYAEVPNNIADEIIKSHNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2017_LACE2
Sequence: MAKRGGFPGGMPGNMNNLMKQAQRMQRQMEEQQAELENKEFSATAGGGVVEVTVTGKREVSKVKIDPEAVDPDDVEMLEDLIVAATNEALRKCEEESQAQMAKITGGLGGLGGGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein EUBELI_02017.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL16_ROSDO
Sequence: MLQPKRTKFRKQFKGSIKGLAKGGSDLNFGTYGLKAIEPERITARQIEAARRAMTRHMKRQGRVWIRIFPDVPVTAKPIEVRMGKGKGSVDRWAAKVKPGRVMFEIDGVNDDVAREALRLAAMKLPIKTRVVVREDW
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL30_RHILO
Sequence: MAKKATKTITVEQIGSPIRRPKEQRATLVGLGLNKMHKQRTLEDTPSVRGMIAAVQHLVRVVDEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: COX4_YEAST
Sequence: MLSLRQSIRFFKPATRTLCSSRYLLQQKPVVKTAQNLAEVNGPETLIGPGAKEGTVPTDLDQETGLARLELLGKLEGIDVFDTKPLDSSRKGTMKDPIIIESYDDYRYVGCTGSPAGSHTIMWLKPTVNEVARCWECGSVYKLNPVGVPNDDHHH
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of COX2 and heme A of COX1 to the active site in COX1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 4, mitochondrial, Cytochrome c oxidase polypeptide IV.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5B family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RS7_BACHK
Sequence: MPRKGPVAKRDVLPDPMYNSKLVTRLINKMMVDGKKGKSQTILYNAFDIVSERTGKEPMEVFEQALKNIMPVLEVRARRVGGANYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEERLANEILDAANNAGASVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: UNG_STAAT
Sequence: MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKPAQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATA_DROME
Sequence: MAGRDAASNQLIDYKNSQTVSPGAITTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFDRERIPERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAVKFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPESAHQVCILFSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRDLYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFAEVEQIAFSPAHLVPGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVNCPYKVKIENFQRDGAMNVTDNQDGAPNYFPNSFNGPQECPRARALSSCCPVTGDVYRYSSGDTEDNFGQVTDFWVHVLDKCAKKRLVQNIAGHLSNASQFLQERAVKNFTQVHADFGRMLTEELNLAKSSKF
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: BETA_CITK8
Sequence: MHFDYIIIGAGSAGNVLATRLTEDSDTTVLLLEAGGPDYRADFRTQMPAALAFPLQGKRYNWAYETEPEPHMNYRRMECGRGKGLGGSSLINGMCYIRGNAMDLDNWAQEPGLEHWSYLNCLPYYRKAETRDIGPNDYHGGDGPVSVATPKHNNNPLFHAMIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKGRPNLTIITHALTDHILFEGKKASGVEWLEGDSTIPTRAMARKEVLLCAGAIASPQILQRSGVGDASLLKAFDIPLVHHLPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGGTGVGASNHFEAGGFIRSSEAFSWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSPSRGHVHIKSRDPREHPAILFNYMSTGQDWQEFRDAIRITREIINQPALDKYRGREISPGITCQTDEQLDAFVRDHAETAFHPCGTCKMGYDEMAVVDGEGRVHGVENLRVVDASIMPQIITGNLNATTIMIGEKMADAIRGREPLAKSTASYYVAGDAPVRQPPLR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.