PharMolix/UniProtQA huggingface dataset:
Protein: FIMC_ECOLI
Sequence: MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEAGVALGATRVIYPAGQKQEQLAVTNNDENSTYLIQSWVENADGVKDGRFIVTPPLFAMKGKKENTLRILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPPDQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGTRVLENALVPPMGESTVKLPSDAGSNITYRTINDYGALTPKMTGVME
What is the function of this protein?
Required for the biogenesis of type 1 fimbriae.  Binds and interact with FimH.
What are the official names of this protein?
Chaperone protein FimC.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: H2A1_CANGA
Sequence: MSGGKGGKAGSAAKASQTRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKPSASQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HDT1_SOLCH
Sequence: MEFWGAEVKSGEPLTVQPGDGMVLHLSQASLGELKKDKSESVCLSVNIDGKKLVLGTLNSEKVPQQQFDLVFDRDFELSHNLKSGSVYFFGYKATNPFEEEEDDEDDYDESDEDIPLTLANSGKPEPKEAGKSNAGKDSASGKQKVRIVEPTKDDEDESSDDDDSDMGEDEDDSDDSEEETPKKAEPAKRRKADSATKTPVTDKKAKLTTPQKTDGKKGGGHVATPHPSKQASKTPKSAGSHHCKPCNRSFGSEGALDSHSKAKHSAGK
What is the function of this protein?
Mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity).
What are the official names of this protein?
Histone deacetylase HDT1, Histone deacetylase 2a, HD2a, ScHD2a.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase HD2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYL_CORDI
Sequence: MTMTNPSGNTPDTSAGPAFRYTAELAGEIERSWQQYWIDNGTFNAPNPVGDLAVSGDKLPEDKLFVQDMFPYPSGAGLHVGHPLGYIATDVFARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIANMQRQLGALGLGHDPRRSVATTDPEFYKWTQWIFLQIFNAWFDTKQQKARPISELIPLLESGEVALPEGFEGSADSYSELDAVEKAKVVDEFRLVYRSHSMVNWCPGLGTVLANEEVTADGRSERGNFPVFRKKLSQWMMRITAYSDRLIDDLDLLDWPDKVKSMQRNWIGRSRGAEVDFDALGHTITVFTTRPDTLFGASYMVLAPEHELVDALVAAGTNSYEGIDPRWTFGQATPAEAVKAYRASIAAKSDLERQENKEKTGVYLGVNAVNPVNGESIPVFIGDYVLTGYGTGAIMAVPAHDTRDYEFATEFGLPIREVVAGGNIAEAAYTESGAAVNSANDQGLDINGLDKQEAIAQVIEWLVDKQKGSEKIQYKLRDWLFARQRYWGEPFPVVYDENGLAHALPESMLPVELPEVEDYKPVSFDPDDADSEPHPPLAKATEWTQVELDLGDGLKKYTRDTNVMPQWAGSSWYQLRYIDPTNSEAFCDIENERYWTGPRSAEDSGGVDLYVGGVEHAVLHLLYSRFWHKVLFDLGFVTSREPYRRLFNQGYIQAFAYTDSRGVYVPAEEVEEKDGKFYYQGEEVNQEYGKMGKSLKNAVAPDDICRDFGADTLRVYEMAMGPLDTSRPWSTKDVIGAHRFLQRLWRLVVSEDDGSIVVTDAALTDDDLKQLHRTIAGMRDDYEGLRINTVVAKAIEYVNYLTKAYGSTGAPRAAVEPLVIMVAAVAPHIAEELWKRLGHNDTITFVPFPEYEDKWLVDDEVEMPVQINGKVRARIMVPADASQDQISEIALASEAVATHIEGKNVIKKIVVSGRMVNLVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPGDS_RAT
Sequence: MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYPRLVSLRNKVQAIPAISAWILKRPQTKL
What is the function of this protein?
Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates.  Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
What are the official names of this protein?
Hematopoietic prostaglandin D synthase, H-PGDS, GST class-sigma, Glutathione S-transferase, Glutathione-dependent PGD synthase, Glutathione-requiring prostaglandin D synthase, Prostaglandin-H2 D-isomerase.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Sigma family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIL1B_ORYSJ
Sequence: MMGGGLVMDQGMMFPGVHNFVDLLQQNGGDKNLGFGALVPQTSSGEQCVMGEGDLVDPPPESFPDAGEDDSDDDVEDIEELERRMWRDRMKLKRLKELQLSRGKDPAGGVVGDPSKPRQSQEQARRKKMSRAQDGILKYMLKMMEVCRAQGFVYGIIPEKGKPVSGASDNLRGWWKEKVRFDRNGPAAIAKYQADNAVPGFESELASGTGSPHSLQELQDTTLGSLLSALMQHCDPPQRRYPLEKGVPPPWWPTGDEEWWPELGIPKDQGPPPYKKPHDLKKAWKVSVLTAVIKHMSPDIEKIRRLVRQSKCLQDKMTAKEISTWLAVVKQEEELYLKLNPGARPPAPTGGITSAISFNASSSEYDVDVVDDCKGDEAGNQKAVVVADPTAFNLGAAMLNDKFLMPASMKEEATDVEFIQKRSASGAEPELMLNNRVYTCHNVQCPHSDYGYGFLDRNARNSHQYTCKYNDPLQQSTENKPSPPAIFPATYNTPNQALNNLDFGLPMDGQRSITELMNMYDNNFVANKNLSNDNATIMERPNAVNPRIQIEEGFFGQGSGIGGSNGGVFEDVNGMMQQPQQTTPAQQQFFIRDDTPFGNQMGDINGASEFRFGSGFNMSGAVEYPGAMQGQQKNDGASEFEELE
What is the function of this protein?
Transcription factor acting as a positive regulator in the ethylene response pathway (PubMed:19798512).  Involved in wound signaling by binding specifically to the DNA sequence 5'-ATGTACCT-3' found in the promoter of some wound-inducible genes (PubMed:19798512).  Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling (PubMed:30002253).
What are the official names of this protein?
Protein ETHYLENE-INSENSITIVE 3-like 1b, EIN3-like protein 1b, OsEIL1b, OsEIL1.
What is the protein family that this protein belongs to?
Belongs to the EIN3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3479_RHOPA
Sequence: MLVCIPEVLPKSEVAEFRRLMDAADWEDGRSTAGAQSAMVKRNEQLPPDSDLARALGRRIVSALTGNPKFVSAAVPLQIFPPLFNRYAASGGHHFGIHVDNAVRGDHLTGLRIRTDLSVTLFLAEPDEYDGGELVIEDTYGSHEVKLAAGDAVLYPSTSLHMVTPVTRGARVASFFWLQSMIRDAQARSMIYDLDNAIQALVERLGRDDPETVKLTGIYHNLIRYWAEV
What are the official names of this protein?
PKHD-type hydroxylase RPA3479.
Protein: NU4M_CERSI
Sequence: MLKIIIPTLMLIPLTWLSKNSMIWINTTAYSLLISFISLPLLSQFNENSLNMSLTFFSDPLSAPLLVLTTWLLPLMIMASQHHLSKEPLARKKLYITMLITLQTFLIMTFTATELIFFYILFEATLIPTLIIITRWGNQTERLNAGFYFLFYTLTGSLPLLIALTHIQNLTGSLNLLLIQYSTQTLPSSWSNAFLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAILLKLGGYGMLRITMILNPLTSYMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAVLIQTPWSYMGATALMIAHGLTSSVLFCLANSNYERTHSRTMILARGLQTLLPLMAMWWLLASLTNLALPPTINLVGELFVVMSSFSWSNITIILMGTNIIITALYSLYMLITTQRGKYTHHINNIKPSFTRENTLMALHLLPLLLLSLNPKIILGTLY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LIPA_CHLL3
Sequence: MKDHSPRKPEWLKQRLSAGDGFGALQRLLSSKGIHTVCRSAKCPNLQECWSEGTATFLLLGNVCTRTCRFCAIDTSRTPAAPETDEPERVAAAARTMALQFVVLTSVTRDDLPDGGAAHWVETIRAIRKASPRAGIECLIPDFAGNEAALDLVCKERPDVLNHNIETVPRLYEKVRPEARYRRSLDLLQRAASLFGLTTKSGMMVGMGESFEEVGEALQDLARHGCRMITIGQYLQPSARHIPVERYVTPEEFAGFRDLALSLGFSSVQSGPFVRSSYHAAASSAACTPVP
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_LACDB
Sequence: MSVVSMKQLLEAGVHFGHQTRRWDPKMKPYIFTQRNDIYIIDLQKTIKMLDDAYNYVKAVAQDDGVFLFVGTKKQAQEAIAEEATRAGQYYVNQRWLGGTLTNWTTIQSRVKRLKDLKKMAEDGTFDVLPKKEVSLLTKEMDKLQKFLGGIEDMPRIPDVMFVVDPKKEKIAVHEANKLGIPVVAMVDTNTDPTPIDVIIPSNDDAIRAIRLIAGTMADAVIEGKQGADNADVEKELSESVEENSAEEVDDAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PURA_PICTO
Sequence: MISVVVGMQFGDEGKGKITDYLCSNYDDVVRFNGGNNAGHTVVIDGKKIKFHLIPSGAMQAGTVVLGNGMVIDPLKLLDEIKQLKLAKDNIKIVISGRAGVVTELHRILDKKEEELRSNSSIGTTSQGIGPAYEDKYGRLSIKMYDLNSIKKIKDKLNQLIAMKGLLTGPVDIDRVSNELYSAGSELYEYIGDASEFLEDEYRLGKNILFEGAQGAMLDIDFGTYPFVTSSNTVAGSVSTGSGFSFRRVEDVIGVFKAYTTKVGSGIFPTEIGSDDLRIAGNEYGTTTGRPRRTGWLDLPILRYAAYLNDVNRLAITKLDILGKLNQIKVGTSYIIDGKDYERFPDKIDPESEITVNYETFETWGDISSRISGYLGSGYDALPYNMRKYIEFIEDSLNCSIDIISLGEDRKSTIVK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S13_MICSU
Sequence: LICYSQMYNEIIKTCENGETTCYSKTWRDHRGTRLEKGCGCPPVKYDMIVKCCKTDRCGN
What is the function of this protein?
Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site.  Binds to and inhibits the endogenous nicotinic acetylcholine receptors (nAChR) in human rhabdomyosarcoma TE 671 cell line with an IC(50) of 346 mM.  This neurotoxin is lethal to mice by intraperitoneal injection and to zebrafish by injection at the back of the dorsolateral region.
What are the official names of this protein?
Three-finger toxin MS3, Short neurotoxin MS3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: QOR_PONAB
Sequence: MATGQKLMRAVRVFEFGGPEVLKLQSDIAVPIPKDHQALIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGGNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSAHVKAGESVLVHGASGGVGLAACQIARAYGLKVLGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDVIIEMLANVNLNKDLSLLSHGGQVIVVGSRGTIEINPRDTMAKESSIIGVTVFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL
What is the function of this protein?
Does not have alcohol dehydrogenase activity.  Binds NADP and acts through a one-electron transfer process.  Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro).  May act in the detoxification of xenobiotics.  Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability.  NADPH binding interferes with mRNA binding (By similarity).
What are the official names of this protein?
Quinone oxidoreductase, NADPH:quinone reductase, Zeta-crystallin.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_DICNV
Sequence: MFTGSLVALVTPMHIDGSIDWQALEALINWHIASQTQAIVVAGTTGEAATLTLDEHKAIMRFCVDIANDRIPIIAGAGANATARAIELTLAAYHCGCAASLQVTPYYNRPPQRGLYAHFAKIAAAAPLPMILYNVPTRTACDIALETVTALAKITHIIGIKEATPHARLAQIRQLFPKNQSFKIYGGEDALCAQAACEGLIDGVISVTANVAPEAMQNMMHCALNGDLKQAQAINQRLAALHESLFCETNPIAVKWALQRMGKIAAGIRLPLMPLDERWHESLTAALVAAGITIQTH
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUAC_GORGO
Sequence: MELVQVLKRGLQQITGHGGLRGYLRVFFRTNDAKVGTLVGEDKYGNKYYEDNKQFFGRHRWVVYTTEMNGKNTFWDVDGSMVPPEWHRWLHSMTDDPPTTKPLTARKFIWTNHKFNMTGTPEQYVPYSTTRKKIQEWIPPSTPYK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12, Complex I-B17.2, CI-B17.2, CIB17.2, NADH-ubiquinone oxidoreductase subunit B17.2.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA12 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: BIOB_SYNR3
Sequence: MSALIRHDWDLAEIEALLELPLVDLLWHAQQVHRDAHPAGYHVQLASLLSVKTGGCEEDCAYCPQSMHHSSDVTAQPELQLQVDGVLQQARSARDAGAHRFCMGWAWREIREGAPFDAMLAMVRGVRELGMEACVTAGMLTDSQAERLAQAGLTSYNHNLDTSPEHYDQIISTRTYQERLDTLQRARDAGLSLCCGGIIGMGESRRDRASLLQVLAGLNPHPESVPINGLVAVEGTPLEDQEPWEPLELVRMVAVARILMPEARVRLSAGRERLSQEAQILCLLAGADSIFYGDSLLTTSNPAVQADQALLAAAGVSSSLEGVAAA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: PUS10_PICTO
Sequence: MDLKELFDLNLCLRCTGRIFAAVDTGLTNEERGARLYFAYKSIYGERDVPESCYLCNGVFKKFDEFFNILMSKLNNYEFNSILVGSTFDENIIEMEKDIQSRFGSKGESIKKEFNREFGKYLSKRLGKPFSKDADLTIEVDALYENVNIIVKPVYIYGVYIKKSRDISQTRWIHKTGESIESIIGNELRSMTGCENYYLHGSGREDVDVMMLGNGREFVIEAAMPKRRYIDLYELQLRVNASGILFIYNLSYSSKATVRRIKSELHEKLYIAEVTGDLNKDIKKACSKFNNLIIEQRTPLRVINHRSDLVRRKKINYINIISIMNGRALLKICAEAGTYIKELVNGDNGRTVPSLSSVYGSQLQVSSLDVVKIYRDD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase Pus10, tRNA pseudouridine 54/55 synthase, Psi54/55 synthase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase Pus10 family.
Protein: Y396_HAEIN
Sequence: MTALSSVDFCLPEHITPEIFLRDYWQKKPLVIRNGLPEIVGQFEPQDIIELAQNEDVTARLVKTFSDDDWKVFFSPLSEKDFQKLPEKWSVLVQNLEQWSPELGQLWNKFGFIPQWQRDDIMVSYAPKGGSVGKHYDEYDVFLVQGYGHRRWQVGKWCDASTEFKPNQSIRIFDDMGELVIDEVMNPGDILYIPARMAHYGVAEDDCLTFSFGLRYPNLSNLIDGISKGFCHQDPDLNLSEFDLPLRLSQSEQRTGKLADENIQAMKQLLLDKLAHSEAFDTLFKQAVASAVSSRRYELLVSDEMCDPDEVRSILEEDGAFLSQDNNCKLLYTENPLRIYANGEWLDELNIIESEVLKRLSDGESLDWAFLSDLANKTEDPETSMDLLLDSICNWVDDGWALIE
What is the function of this protein?
Oxygenase that catalyzes the hydroxylation of a ribosomal protein.
What are the official names of this protein?
Probable ribosomal oxygenase HI_0396, ROX.
What is the protein family that this protein belongs to?
Belongs to the ROX family.
Protein: LUXS_ECOK1
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: DAPE_PSESM
Sequence: MTAPADLSPTLQLACDLIRRPSVTPVDADCQTVMMQRLGDAGFKLEPMRIEDVDNFWATHGTREGPVLCFAGHTDVVPTGPVQDWQNDPFDALIDEHGMLCGRGAADMKGSLAAMLVAAERFVADHPDHKGSVAFLITSDEEGPAHHGTKAVVERLAARNERLDWCIVGEPSSTTLVGDVVKNGRRGSLGAKLTVRGKQGHVAYPHLAKNPIHLATPALAELAAEHWDNGNDFFPPTSFQISNLNSGTGATNVIPGDLVAVFNFRFSTESTVEGLQQRVAAILDKHELDWHVDWALSGLPFLTEPGALLDAVSSSIKSVTGRDTKASTSGGTSDGRFIATLGTQVVELGPVNATIHQVNERILASDLDVLTEIYYQTLVKLLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: ZIPA_ECO45
Sequence: MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPRQPVQQPPEAQVPPQHAPRPAQPVQQPVQQPAYQPQPEQPLQQPVSPQVASAPQPVHSAPQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: LIPL_ANOFW
Sequence: MMSELLQQQTWRVIDHTSLGPSFDAKQSFAFDDALCESVGSGQSQPVVRLWVHHQTVVLGIQDTKLPYIEKGLAYLHEQGWRTIVRNSGGLAVVLDEGVLNVSLIFPDTKKGIDIDRGYEAMATLIAHMLPEAHVQTGEVVGSYCPGSFDLSINGKKFAGISQRRIRGGVAVQVYICVNGSGAERAGWIREFYERSLAGEQTKFTYPTIVPHTMASLSELLSKEMTVSALVIRLYEALQAFGSRLEPSSLTPAEWERYYMYFQRMIDRNETMLPT
What is the function of this protein?
Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
What are the official names of this protein?
Octanoyl-[GcvH]:protein N-octanoyltransferase, Octanoyl-[GcvH]:E2 amidotransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipL family.
Protein: HSLO_ENTFA
Sequence: MEDYLVKALCYKGSIRAYAISATETVSEAQRRHDTWSSSTAALGRTLIGALLLGATLKGDDKLTVKVQGNGPAGAIIVDSNGRGETKGYIKNPHVSLKLNATGKIDVRGAVGNEGIFTVIKDLGLKETFSGQTPIVSGEIGEDFTYFMAVSEQVPSAIGLGVLVDTDESVKAAGGFMIQVMPGADESTIDFIEQRLAEVPPISQLLENGETPEQVLYRLLGEDEVEILEKMPVQFKCDCSKEKFATALIAVGIDELNAMIDEDHGAEAVCQFCNNKYHYSEEELIELRDEAIRNTKQK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_NEIM0
Sequence: MSLIEFLFGRKQKTATVARDRLQIIIAQERAQEGQAPDYLPTLRKELMEVLSKYVNVSLDNIRISQEKQDGMDVLELNITLPEQKKV
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RL35_CYTH3
Sequence: MPKVKTKSGAKKRFKLTGSGKIKRKSAYHSHILTKKSTKRKRNLVHAHLVSAADESNVRAMLKI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PGK_GEOMG
Sequence: MAIRYIDEIESLKGKKVFIRVDFNVPLDEHQNITEDTRIRAVLPTINFALDAGAKVILASHLGRPKGERKPKYSMAPAAKRLSRLLNKEVQLAPDCIGDEVKKMIDAMKPGEVLLLENVRFYEGEEKNDADFAKALANDCEIYINDAFAVSHRAHASVEAITKFFPVVAAGFLMNNEINYFEKAMQKPIRPLVAILGGAKVSGKLEVLESLVNKVDKIIIGGGMAFTFLKALGYNVGKSLVEEELLEIALTTYTKAREKGVKFYLPVDCVAADRFNPEAETKVTTIQEIPEEWMALDIGPATVTLFTEALQNAKTIIWNGPMGVFEMDAFSRGTFAMVSAVANSYALTIVGGGDTDSAVHRAGEYAKISYISTGGGAFLELLEGKHLPGIKVLEENGK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_NITEU
Sequence: MRKIYNFSAGPAVLPEEVLEQAREEMLDWHGSGMSVMEMSHRGKEFMSIADETESALRELAGIPDHYKVLFLQGGASSQFAMVPMNLLGKKGKADYVNTGQWSAKAISEAKNYGSVQIAASSESDGFNSVPPLAQWHISPDAAYVHYASNETIGGVEFQWTPDLSAVAGDNKNIPLVADMSSNFLSRPFDVSKFGLIYAGAQKNVGPAGLVVVIVREDLLDIPPLAGTPAMFRYKTHADNASMYNTPPTYAIYIMGLVMEWLKKQGGLTAIEQRNIAKAKLIYDLIDVSSFYHCPVNQADRSRMNVPFTLSDPGLDDAFLKQAQAHGLIQLKGHRSVGGMRASIYNAMPLEGVQTLVTFMREFEKNHA
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOW_METRM
Sequence: MKLMMYSIKMRSAKGGPHEEGGKHISGAERILREDEIEEELINVYRRAITHEKGKPDFINLKIEAIDEDKILYKKRLNIIQHKVSSKEEGLKLAKELLIKNTVSEEAAKEGISSIQKLKESIHGAMLLDKDSGKRIDDKGIKGVRVTGIASADIKKYKESLKRDGREGLHLEEALILASKIASCKAIVAELCWSDDPSYVIGYVGTKENYHRIPILKDKGNPVGGRVFFVDTSQLNDNYTLEDLIDYLEKQIVLIE
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.