PharMolix/UniProtQA huggingface dataset:
Protein: TACY_STRP8
Sequence: MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSELTTEKAGQKTDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTPVDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHRGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYGSITYK
What is the function of this protein?
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes.  After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex.  Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus.  Can be reversibly inactivated by oxidation.
What are the official names of this protein?
Streptolysin O, SLO, Thiol-activated cytolysin.
What is the protein family that this protein belongs to?
Belongs to the cholesterol-dependent cytolysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Probably secreted as soluble protein by the accessory Sec system (By similarity). It then inserts into the host cell membrane and forms pores formed by transmembrane beta-strands (By similarity).
Protein: WDR91_BOVIN
Sequence: MAEAVERTDEMVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAALRDYWNYLERRLFSRLEDVYRPTINKLKTSLFRFYLVYTIQTNRSDKAQEFFAKQASELQNQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNFDAECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQPEEEEALVQHKLPPYVSNMDRLGDSELAMVCSQRNASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQTQSSAKKESFGSQTTKGREPAGAPKDGKSLFGGLAPGESSWSQHRQRRLQDHGKERKELLSMTLQCAEKKPEAGGPEAEPCPEPHVEALETLTRVPTAGPEGGGVRPEQPFIVLGQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDDMPRILSLACSPSGASFVCSAAASSLTAHVDVLAPDIGSRGTNQVPGRLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWKAHCGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKVSEYGLPADATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGVIYKLGGDDKVLESCVSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKV
What is the function of this protein?
Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex.  By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport.  It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome.  May play a role in meiosis.
What are the official names of this protein?
WD repeat-containing protein 91.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR91 family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein. Late endosome membrane.
Protein: NDHI_TRIEI
Sequence: MFKFLKQVSDYAKETFQSAKYIGQGLSVTFDHMSRRPVTVQYPYEKLIPSERFRGRIHFEYDKCIACEVCVRVCPINLPVVDWEFNKETKKKKLKHYSIDFGVCIFCGNCVEYCPSNCLSMTEEYELAAYDRHELNYDNVALGRLPYKVTNDPMVTPMRELAYLPKGVIDPHTVPHTSRRAGLRPEEILEQIEAEKTAAEKTAAEITDK
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: O16B_CONMR
Sequence: MKLTCMMIVAVLFLTAWTLVMADDSNNGLANHFLKSRDEMEDPEASKLEKRACSKKWEYCIVPILGFVYCCPGLICGPFVCV
What is the function of this protein?
MuO-conotoxins are gating-modifier toxins that inhibit sodium current by trapping the domain II voltage sensor in the closed position to prevent opening of the sodium channel.  This toxin has a preference for Nav1. 4/SCN4A over Nav1. 2/SCN2A sodium channels.  It blocks Nav channels by interacting mainly with the C-terminal part of the pore loop of domain-3.  It also blocks fast-inactivating calcium current.  Blocks Nav1. 8/SCN10A sodium channels and has potent and long-lasting local anesthetic effects.  It can also block propagation of action potentials in A- and C-fibers in sciatic nerve as well as skeletal muscle in isolated preparations.
What are the official names of this protein?
Mu-conotoxin MrVIB, CGX-1002.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: H8A18_CYRHA
Sequence: MVNTKASMFLTFAGLVLLFVVCYASESEEKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCSGYVCSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1a 18, U3-TRTX-Hhn1a, Hainantoxin-VIII.18, HNTX-VIII.18, Peptide F4-27.90.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HUTH_BRADU
Sequence: MTEQDAAIVVKPGTVSLDDLARVLAGQPVVLDPSFWPRVEAAAAIVAKAAQADTPVYGINTGFGKLASKRIPPDQTALLQRNLIVSHCCGVGPATPEPIVRLMMALKIISLGRGASGVRREVIEQLQGMLARRVCPLVPQQGSVGASGDLAPLAHMTAVMIGEGQAIVDGKTVSGGEALAAAGLAPLTLGPKEGLALINGTQFSTAYAISGVLRGFHLARAALVTGALSVDAAMASTAPFRPEIQALRGHAGQIAAAATLTALLDGSDIRLSHLEGDERVQDPYCLRCQPQVAGAALDLITQTARALIVEANAVTDNPLVLVETGEIVSGGNFHAEPVAFAADTIALALSEIGAISERRIATLVDPALNFGLPPFLTPDPGVNSGFMIAEVTAAALYAENKQRAAACSIDSTPTSANQEDHVSMAAHAARRLADMADNLAAILGIELLVAAQGITLRAPHATSAPLVAVIAALREQVPALGADRYMAGDLAKAAALVEADALPAAAIGVLPSDPFPRLA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AV262_PHYSO
Sequence: MLPVAVVLVVFAVAVTSAESIHQVNPLPRRRRLKGTEEKGHHTNVNDEERVISLESASDLISKLKVKINAKLLAGDSAKPATLSKAQVASVAKEVVKEVKKTPKVWPPPMIKKGVRRGAGGVR
What is the function of this protein?
Effector that suppresses plant defense responses during the early stages of pathogen infection.  Suppresses cell death induced by effectors and PAMPs in plant hosts (PubMed:21653195, PubMed:27256489).  Avh262 stabilizes endoplasmic reticulum (ER)-luminal binding immunoglobulin proteins (BiPs), which act as negative regulators of plant resistance to Phytophthora.  By stabilizing BiPs, Avh262 suppresses ER stress-triggered cell death and facilitates Phytophthora infection (PubMed:27256489).
What are the official names of this protein?
RxLR effector protein Avh262, Avirulence homolog protein 262.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host endoplasmic reticulum.
Protein: HTPX_SULSY
Sequence: MANQLKTVLLLGVLTGLFLAIGHLVAGKQGMIIAFVVALFMNFFSYFFSDKVALAMYGAREIMYEEAPWLHEMVEDLAKRAGIPKPKIYLAPIAVPNAFATGRDPNHAAVAVTSGILQILDKDELRGVLAHELGHVKNRDILISSIAATIGGAISMLANMAYYTAFLGGNDRENNNPIASIIGSIILFIVAPLAATLIQMAISRSREFVADEAGAKISGCPLCLANALRRLEEIAHNPQIQEIASQEINPGTAHMMIVNPLSGDFIMKLFSTHPPTEERIRRLEELARKMQPGYGF
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYA_SPHAL
Sequence: MTSTNDIRRSFLDYFGGAGHHIEPSAPLVPYNDPTLMFVNAGMVPFKNVFTGLEKRPYSTAASSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEQAIHHAWTLITQTWGLAPEKLTATVYHTDDEAFDLWKKIAGLPDERIIRIPTSDNFWSMGDTGPCGPCSEIFYDHGDHVRGGPPGSPEEDGDRFVEIWNLVFMQYEQLPGGERVDLPRPSIDTGMGLERVAAVLQGVHDNYDTDTFKALIEASVELTGVRADEAHRASHRVIADHLRASSFLVADGVLPSNEGRGYVLRRIMRRAMRHAHLLGAKDPLMHRLLPSLTAEMGAAYPELIRAQPLIAETLEREEVKFRQTLDKGLRLLDEATADMGRGDTLVGDVAFKLYDTYGFPYDLTEDALRSKGISVDRAGFDAAMAQQKAAARAAWKGSGQKASEEIWFDLAETHGSTEFTGYTSTSGEATVIALVRDGQPVEEARAGDEVIVLTNQTPFYGESGGQMGDAGMIATLEGAKASVSDTGKPLGRLHTHQAKLEAGTLKVGDTVQLTVDAERRDRIRANHSATHLLHAALRNRLGGHVTQKGSLVAADRFRFDFSHPKALTAAEIADIEADVNAQIRGNEPVTTRLMTPDDAIAAGALALFGEKYGDEVRVLAMGKADDRNYSVELCGGTHVRALGDIALFKIVSESAVSSGVRRIEALTGEAARQWLNGRDEALKAAAAALKTSPDEVPARVAQLAEQLKKAERELADAKKALALGGSGGDGGAAAGPAVEQVGDVAFLAQVVDGLDPKELRGTVDGLKKQVGSGVAMLVAVNDGRASVAVGVTDDKTGHHSAVDLVKAAVVALGGQGGGGRPDMAQGGGPNGGAANDAVAAVKAALA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4LR_SINFN
Sequence: MVKIAEACLNVLYQHGLSSAQFQFWFERAKHDLLADGMACDAIVAEVMQSMDDHPDAATLFGLLLDEARMGIENDSPYGKAFLENAEKAIRARIAADAFEPLHRLKIAGLYRRAGLPVPDILMLDPEGEGAADEIAMPDLGGVLAVLAAEVEAEGGGAYEFFSGLDEMTAGMPEGAKAGFIHHLMSLDNPFLERCALYWLVSGAALTREAVADGLRERLMRGELQPETASYLPIIRGWLPASAARAAIDDIGKLSRRQGLADASNQNRAEPIVSDIMATTADGVGAQGLTIVGKLQARTFVAMILLKTGYGIKDAFVIRCRSKSEATNIVSYARQEANSVKIDRMTAELLLEAALADGMKNGHPPAPGFIDVIEACSLSQLRPQERDLQALLEHVDPQKEIQNATAAELNRMLRNASALDALVPFTDSWFEDTGETRGIIQGSRSVRTVEKRIWAFLEGRRDIWARRFLQTAIILKSAKKERMSKALAAAAFAVMHKHPLQDIPLMKDIAMTTLDAGGGSPW
What are the official names of this protein?
Uncharacterized protein y4lR.
Protein: FABG2_BRANA
Sequence: MATTSIAGPRLTSLKTAAGKLGYREICHVRQWAPVHSPMPHFGMLRCGSRRPFATSSSTVVQAQAQATAAEQSTGEEEAVPKVESPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKEAEQVSKQIEAYGGQAITFGGDVSKEADVDAMMKTAVDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPGFIASDMTAKLGEDMEKKILGTIPLGRYGQPEDVAGLVEFLALSPAASYITGQAFTIDGGIAI
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase 2, chloroplastic, 3-ketoacyl-acyl carrier protein reductase 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid. Note=And non- photosynthetic plastids.
Protein: Y4HR_SINFN
Sequence: MEIDEDKIDDAVLALLWLTLHNERCAWKGFDWATTDRLHERGLICDPVNKSKSLVLTDEGLRRSEELFRRLFTR
What are the official names of this protein?
Uncharacterized protein y4hR.
Protein: SPUD_PSEAB
Sequence: MMKRFGKTLLALTLAGSVAGMAQAADNKVLHVYNWSDYIAPDTLEKFTKETGIKVVYDVYDSNEVLEAKLLAGKSGYDVVVPSNSFLAKQIKAGVYQKLDKSKLPNWKNLNKDLMHTLEVSDPGNEHAIPYMWGTIGIGYNPDKVKAAFGDNAPVDSWDLVFKPENIQKLKQCGVSFLDSPTEILPAALHYLGYKPDTDNPKELKAAEELFLKIRPYVTYFHSSKYISDLANGNICVAIGYSGDIYQAKSRAEEAKNKVTVKYNIPKEGAGSFFDMVAIPKDAENTEGALAFVNFLMKPEIMAEITDVVQFPNGNAAATPLVSEAIRNDPGIYPSEEVMKKLYTFPDLPAKTQRAMTRSWTKIKSGK
What is the function of this protein?
Putrescine-binding protein probably required for putrescine uptake into cells.  Binds putrescine with high affinity, spermidine with relatively low affinity.  Does not bind cadaverine or spermine.  Putrescine binding induces large inter-domain conformational changes.
What are the official names of this protein?
Putrescine-binding periplasmic protein SpuD.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein PotD/PotF family.
What are the subcellular locations of this protein?
Periplasm. Secreted. Note=Could be present extracellularly due to cell outer membrane leakage.
Protein: SYR_UREP2
Sequence: MITQKISEELNKALAKMGIHDTQETKILVDKTKNIKFGDFYTNIAMILSKKNNKSSLEIAKEIANNFEQDLFLEVNLQPPGFLNFKLKAKDHENLLKQIYYEKDRFGQFSKKNITYNIEYVSANPTGYLHIAHAANAIYGDILANLLKIYGYDVETEYWINDAGNQIDKLAMSVLVRYLQLQNINIQLPADAYHGQEIHLVAQTLYQTYKNQFINVRLNEKYEIDDDIANQEIKNFAVKYLLNEIKNDLASINTFIDTYTSENWIRNSGRILEVLSKIKPYTYTLDGALWLKTTTFGDDKDRVLIKSDGSYTYFTPDIAYHDYKFNKTNTTKLIDVWGTDHLGYIARLKAAMNALGYDPNNLEIVCAQVMKLVKNNQEFKLSKRSGQSLTIKDLVEIIGKDALRWFLGSSSMNSHVIIDVDIALSKNNNNPLYYVQYAHARANQVLNKQVYELDFKTDLLTETRERELLNQLHFYKQTIANAANNREPHRISNYLYDLAQIFHNYYANVKINNDNNKVLSAQRYTLVWCVKQVLANGLAIMKITPYDQMY
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_COXB2
Sequence: MTTITPIMVKELRERTGAAVMACKKALQETNGDMEAAIDLLRKAGDAKAAKRAGKTAAEGVIVIAISKDQKKGFMAEVNSETDFVARDTNFMAFASKVAERGLAEGVSDVAATLALPIEPNSSSTIEDERKALVNRIGENIQIRRVASLSSDGVVGHYSHGGRIGVLLALDVPNPELAKGLAMHVAAFNPQAVSANQVSTEFVEKEKEIFLARAQETGKPANIIEKMVKGQVEKLLKEVSLEGQSFVKDPEKLVGDLLKAEKAKVLAFLRFEVGEGVEKESQNFADEVMAQVQGNR
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBIX_ECO45
Sequence: MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSALYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPESYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGESEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.
Protein: PLSY_ALISL
Sequence: MTPLALIMIIIAYLLGSISSAVLICRLRGLPDPRTSGSQNPGATNVFRLGGKGAAGLVLLCDILKGMLPVWGGYFLESNPLLLGIIAIAACLGHMYPLFFHFKGGKGVATALGALAPIGLDLTGLLFGTWVVIVLITGYSSLASMATALLAPLFTWLVKPQYTLPVAMLSCLIVLKHHENIRRFFAGKEKKIW
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COXX_ANADE
Sequence: MTVATAQARTAPQPLAYLKDLVLLSKPRLSGLVMITCAGGMWLAPGQIGAARAVLTVLATAVVVGAANALNCYLERDIDARMRRTRDRPLPAGRVDPFVALGLGIAAPAFAIPILSLAANGLTALLALVALLTYVLVYTPMKQRSATALFVGAVPGAIPPLMGWTSVTGGVDAGGLALFGLLFAWQLPHFLAISLYLREDYQRGGLRMFASVHGERATRLWMALTTILLLPASLALVPLGLAGTGYAITAAVLGLALSAYAISGIGREGGRWARTFFLGTLVHLTVLFVALFLSR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ILVD_PELPB
Sequence: MRSDTIKTGFEKAPHRSLLKATGSIVSNNDFKKPFIGICNSYNELIPGHSHLQELGRIAKEEVRKAGGVPFEFNTIGVCDGIAMGHIGMRYSLASRELIADSVETVAQAHCLDGLVCIPNCDKITPGMMMAALRINIPVIFVSGGPMKAGHTPSGQTVDLISVFEAVGQFSAGKIGNEELESIEESACPGCGSCSGMFTANSMNCLSEALGFALPGNGTILAIDPRRNELVREASRRIIDLVKKDIKPRDILSRNALLNAFALDFAMGGSTNTILHTLAIANEAELDFNFSELNALSAKTPYICKVSPATMAVHIEDVDRAGGVSAILHELSRIDGLLDLSTLTVTGKTLGENIADAEILDYTVIRSIDEPYSATGGLAVLFGNLAPQGAVVKTGAVAPEMMKHTGPAKIYDCQDDAIKGIMGDDVKAGDVVVIRYEGPKGGPGMPEMLSPTSAIMGRGLGESVALITDGRFSGGSRGACIGHISPEAAERGPIAALHNGDLITIDIPSRSISVNLTEETINERLAALKPFEPKIKKGYLARYAQMVTSANTGAILKNPVSCEPK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: ARGB_CHLPM
Sequence: MDHQACNDTTPARKAPQAAIGQVLIEALPYIRKFEGKTFVIKYGGSAMKDECLKNSFAQNVTLLRKVGINVVLVHGGGDAITKTAEKMGIKSTFVHGKRVTDSDMITIVQMTLAGKVNQDIVRLISEHGGKAVGVSGLDADTIQAVPCHNAETLGLVGEVAAINTAYIDLLCNAGLIPVIAPIGFDDEGHVYNINADDAASSIAIALKAEKLIYVSDVAGIQAHDAILRTISKTQAADFIEQHVITGGMIPKVISAFQTLDGGVGKIHLIDGKCIHSILLEIFTHEGVGTQFIAEQGNDDNQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE_SHEPA
Sequence: MAKQIALPRSQTSPLFQWRAYYEMTKPKVVALMLLTVLVGMCLAVPGTVPLVPLIAGMAGIGMMAGSAAAFNHLIDRRIDGLMARTYNRPLPKGRISIIKAISFASILGTLGFIILYALVNPLTAWLTFASLIGYAVVYTAYLKRATPQNIVVGGLAGAMPPLLGWTAVTGEFHGNALLLVIIIFAWTPPHFWALAIHRKAEYAKVDIPMLPVTHGVEFTKTCIFLYTVLLAIACLLPVLVGMCGPVYLVSSTLLSAGFIYKAWQLKFHETPGLAMNVFKFSIYHLMLLFIALLVDHYLWV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLID2_PSEAE
Sequence: MAGISIGVGSTDYTDLVNKMVNLEGAAKTNQLATLEKTTTTRLTALGQFKSAISAFQTALTALNSNAVFMARTAKSSNEDILKASATQSAVAGTYQIQVNSLATSSKIALQAIADPANAKFNSGTLNISVGDTKLPAITVDSSNNTLAGMRDAINQAGKEAGVSATIITDNSGSRLVLSSTKTGDGKDIKVEVSDDGSGGNTSLSQLAFDPATAPKLSDGAAAGYVTKAANGEITVDGLKRSIASNSVSDVIDGVSFDVKAVTEAGKPITLTVSRDDAGVKDNVKKFVEAYNTLTKFINEQTVVTKVGEDKNPVTGALLGDASVRALVNTMRSELIASNENGSVRNLAALGITTTKDGTLEIDEKKLDKAISADFEGVASYFTGDTGLAKRLGDKMKPYTDAQGILDQRTTTLQKTLSNVDTQKADLAKRLAALQEKLTTQFNLLSAMQDEMTKRQKSITDNLASLPYGSGKKT
What is the function of this protein?
Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament.  Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.  Essential for motility.  Responsible for adhesion to mucin, which is the initial event in colonization by this organism of the airways of cystic fibrosis patients.
What are the official names of this protein?
B-type flagellar hook-associated protein 2, HAP2, Filament cap protein, Flagellar cap protein.
What is the protein family that this protein belongs to?
Belongs to the FliD family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RBFA_YEREN
Sequence: EFSRSQRVSQEMQKEIALILQREIKDPRVGMATVSGIELSRDLAYAKVFVTFLNVLTDNADPDTAKNGIKALQDASGYIRTLLGKAMRLRIVPELTFAYDNSLIEGMRMSNLVTNVIKNDVERQVNPGSDEEK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUMC_RICCN
Sequence: MKNYRTESDSFGEIQIEEKFYWGAQTQRSLENFKIGKQKMPEILIRALAILKKCAAQVNHEFGDLEAKIAISIDKATDRILEGEFEDNFPLVVWQTGSGTQTNMNMNEVIASIANEELTGKKGGKSPVHPNDHVNKGQSSNDSFPTAMHIATVLATKQQLIPALNNILTSLQDKSKDWDKIIKIGRTHLQDATPLTLKQEFSGYITQIEYALERIENALQKVYLLAQGGTAVGTGINSKIGFDIKFAEKVAEFTKQPFKTAPNKFESLAAHDALVEFSGTLNTIAVSLMKIANDIRLLGSGPRCGLGELHLPENEPGSSIMPGKVNPTQVEALTMVCSQVMGNHVTVTIAGSNGHLELNVFKPVIIYNILQSIELLSDSVNSFVTHCVKGLEPNIARINDLRDKSLMLVTALNPHIGYDNAAKIAKEAHKHGITLKEAAKKLNLLSEAKFDKIVVPEKMVSQS
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_CARRU
Sequence: MTLNQILKFKRKKSVKKKKTPALLSSPQKKGICIKVYTTTPKKPNSALRKVCRVKLSNKNEITAYIPGEGHNLQEHSNVLVRGGRVKDLPGVKYHIIRNVYDLSGVINRKTSRSKYGKKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MDTB_SALA4
Sequence: MQVLPPGSTGGPSRLFILRPVATTLLMAAILLAGIIGYRFLPVAALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPIYSKVNPADPPIMTLAVTSNAMPMTQVEDMVETRVAQKISQVSGVGLVTLAGGQRPAVRVKLNAQAVAALGLTSETVRTAITGANVNSAKGSLDGPERAVTLSANDQMQSADEYRRLIIAYQNGAPVRLGDVATVEQGAENSWLGAWANQAPAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSQQSLRKQNRFSRACERMFDRVIASYGRGLAKVLNHPWLTLSVAFATLLLSVMLWIVIPKGFFPVQDNGIIQGTLQAPQSSSYASMAQRQRQVAERILQDPAVQSLTTFVGVDGANPTLNSARLQINLKPLDARDDRVQQVISRLQTAVATIPGVALYLQPTQDLTIDTQVSRTQYQFTLQATTLDALSHWVPKLQNALQSLPQLSEVSSDWQDRGLAAWVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTASTPGLAALETIRLTSRDGGTVPLSAIARIEQRFAPLSINHLDQFPVTTFSFNVPEGYSLGDAVQAILDTEKTLALPADITTQFQGSTLAFQAALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALIIAGSELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIFQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIAMVGGLLVSQVLTLFTTPVIYLLFDRLSLYVKSRFPRHKEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.