PharMolix/UniProtQA huggingface dataset:
Protein: ZEN1_DROME
Sequence: MSSVMHYYPVHQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGTAAAEKRPMMAVAPVNPKPDYQASQKMKTEASTNNGMCSSADLSEILEHLAQTTAAPQVSTATSSTGTSTNSASSSSSGHYSYNVDLVLQSIKQDLEAAAQAWSKSKSAPILATQSWHPSSQSQVPTSVHAAPSMNLSWGEPAAKSRKLSVNHMNPCVTSYNYPN
What is the function of this protein?
Required for the differentiation of the dorsal-ventral pattern, and does not appear to be involved in the process of segmentation.
What are the official names of this protein?
Protein zerknuellt 1, ZEN-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPORB_IPOBA
Sequence: MKALALLFVLSLYLLPNPAHSKFNPIRLRPAHETASSETPVLDINGDEVRAGENYYIVSAIWGAGGGGLRLVRLDSSSNECASDVIVSRSDFDNGDPITITPADPEATVVMPSTYQTFRFNIATNKLCVNNVNWGIKHDSESGQYFVKAGEFVSDNSNQFKIEVVNDNLNAYKISYCQFGTEKCFNVGRYYDPLTRATRLALSNTPFVFVIKPTDM
What is the function of this protein?
Major tuberous root protein.
What are the official names of this protein?
Sporamin B.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Vacuole.
Protein: AQP4_HUMAN
Sequence: MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGEVLSSV
What is the function of this protein?
Forms a water-specific channel (PubMed:7559426, PubMed:8601457, PubMed:19383790).  Plays an important role in brain water homeostasis and in glymphatic solute transport.  Required for a normal rate of water exchange across the blood brain interface.  Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways.  Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP.  Plays a redundant role in urinary water homeostasis and urinary concentrating ability (By similarity).
What are the official names of this protein?
Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection. Note=Activation of the vasopressin receptor AVPR1A triggers AQP4 phosphorylation at Ser-180 and promotes its internalization from the cell membrane. Detected on brain astrocyte processes and astrocyte endfeet close to capillaries.
Protein: CODY_LISMF
Sequence: MTLLEKTRKINAMLQNAAGKTVNFKEMADTLTDVIEANTYIVSRKGKLLGYSEALPIENDRMKQMLTERQFPEEYTQSLFNVGETSSNLEVSSQYTAFPIENSELFTKGLTTIVPIVGGGERLGTLILSRLESNFTDDDLLLAEYGGTVVGMEILHEKAEEIEEEARSRAVVQMAISSLSYSELEAIEHIFDELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIDSRSLGMKGTFIRVLNDKFLVELEKLKNN
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP70_AJECA
Sequence: MAPAVGIDLGTTYSCVGIFRDDRIEIIANDQGNRTTPSFVAFTDTERLIGDAAKNQVAMNPANTVFDAKRLIGRKFADPEVQADMKHFPFKITDKGGKPVIQVEFKGETKEFTPEEISSMVLTKMRETAEAYLGGTVNNAVVTVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDKKADGERNVLIFDLGGGTFDVSLLTIEEGIFEVKSTAGDTHLGGEDFDNRLVNHFVSEFKRKFKKISPAERARALRRSPTACERAKRTLSSAAQTSIEIDSLYEGIDFYTSITRARFEELCQDLFRSTMEPVERVLRDAKIDKSSVHEIVLVGGSTRIPRIQKLVSDFFNGKEPNKSINPDEAVAYGAAVQAAILSGDTSSKSTNEILLLDVAPLSLGIETAGGVMTPLIKRNTTIPTKKSETFSTFSDNQPGVLIQVFEGERARTKDNNLLGKFELTGIPRARGVPQIEVTFDVDANGIMNVSALEKGTRKTNKIVITNDKGRLSKEEIERMLAEAEKYKAEDEAEASRIRPKNGLESYAYSLRNSLRHSKVDEKLEAGDKEKLKSEIDKTVQWLDENQTATKEEYESQQKELEAVANPIMMKFYAGGEGAPGGFPGAGGPGGFPGGPGAGHASGGGDDGPTVEEVDLKFPMLPLPWQLSVRKMHRPFFLFLLFLIFLIFLILFLFYFFLPVRFNESCFS
What are the official names of this protein?
Heat shock 70 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RR14_CARPA
Sequence: MAKKSLIHREKKRQKLEQKYHLIRRSSKKEISKVPSLSDKWKIHGKLQSSPRNSAPTRLHRRCFSTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFPL_XANCB
Sequence: MKANDIKKGNVVEYNGGIYQIRDIERSSPQGRGGNVRFRFIMYSVPGGAKLDASFDADDNLPEVELLRRQSTYSYKDGEAFVFMDDEDYTPYMLDAEVIGTDAGYITDGLTGIFVQVIDDQPVAVQLPQTVTLEVVETPPELKGGTATKRPKPAKLNTGLEIMVPEYITNGERVLVNTTTGEFAGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: LPTD_SHIFL
Sequence: MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKFLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYHYASPEYIQATLPKYYSTAEQYKNGISQVGAVASRPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: DMRTC_RAT
Sequence: MQRPSGSREVRKAVSAVSASKKEQATRVKKHVVRRQKGTMAAAPKSHVHVKKLTVEEGVRTGKNSVHQLQAQVDTATQQESSQGPVLLSQLPETTSVPYTPETMGQQLTVSLSGEPYGPSAMPSMCPSLILQPCATTDPMLLQPQGSSASNQASVSATLEWQEMLEAAEALLALKNSSQTRHQPCGMPGTAGERGLQLPNPSMPPRPASSGSLPSGHLDCMSLLT
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor C1.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
Protein: ARGE_YERPE
Sequence: MKMKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFAANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIPYPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVGVIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_HELHP
Sequence: MKIIAVLGSSGSGKSALAHRIAMEQNCKIFSLDSLSIYKYLDIASAKPTLLEQSQVCYYALNILEPHQKSNVMIFKDLLLQSIEDIKNNSPHTPLLIVGGSSFFLKSIMEGLSPMPPLEEHEEWVKSLGNISMQYAQLTQIDKTYAQSLSPTDTYRICKALALFKATNTPPSIYFATHKKESLGYDIEIFCLECERDELRERIAKRTKAMIQKGIVEEVQNVLEAYGAQAPALNAIGAKECVNFLQGKVATLQQLEEQIFFHTCQLAKRQRTFNRTQFAQITHLKEKALEAQLIQQIHNNIL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PLSY_SHIFL
Sequence: MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPISWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TYSY_SHV21
Sequence: MSTHTEEQHGEHQYLSQVQHILNYGSFKNDRTGTGTLSIFGTQSRFSLENEFPLLTTKRVFWRGVVEELLWFIRGSTDSKELSAAGVHIWDANGSRSFLDKLGFYDRDEGDLGPVYGFQWRHFGAEYKGVGRDYKGEGVDQLKQLIDTIKTNPTDRRMLMCAWNVSDIPKMVLPPCHVLSQFYVCDGKLSCQLYQRSADMGLGVPFNIASYSLLTCMIAHVTNLVPGEFIHTIGDAHIYVDHIDALKMQLTRTPRPFPTLRFARNVSCIDDFKADDIILENYNPHPIIKMHMAV
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: RENT1_ARATH
Sequence: MDSQQSDLFDTASQPDTVADEYTFLEFNTQGDSEFDYQDFGSPTAWPTPSDSISIADVADRGEGGAAADHHSEASSPSSLSAGAGNGAKVGRGGVGGSGGVSSSSQVDALAAGVGNLNFEETGDDDGFDYGKNDFTEHACKYCGISNPACVVRCNVASCRKWFCNSRGNTSGSHIVNHLVRAKHKEVCLHRDSPLGETILECYNCGCRNVFLLGFISAKTDSVVVLLCRDPCLNVNALKDMNWDLSQWCPLIDDRCFLPWLVKVPSEQEQLRARQISAQQINKIEELWKTNPDATLEDLEKPGVDDEPQPVQPKYEDAYQYQNVFAPLIKLEADYDKMMKESQSKENLTVRWDIGLNKKRVAYFVFPKEENELRLVPGDELRLRYSGDAVHPSWQSVGHVIKLTAQEEVALELRANQGVPIDVNHGFSVDFVWKSTSFDRMQGAMKNFAVDETSVSGYIYHQLLGHEVEAQMVRNTLPRRFGVPGLPELNASQVNAVKSVLQKPISLIQGPPGTGKTVTSAAIVYHMAKQGQGQVLVCAPSNVAVDQLAEKISATGLKVVRLCAKSREAVSSPVEYLTLHYQVRHLDTSEKSELHKLQQLKDEQGELSSSDEKKYKNLKRATEREITQSADVICCTCVGAADLRLSNFRFRQVLIDESTQATEPECLIPLVLGVKQVVLVGDHCQLGPVIMCKKAARAGLAQSLFERLVTLGIKPIRLQVQYRMHPALSEFPSNSFYEGTLQNGVTIIERQTTGIDFPWPVPNRPMFFYVQLGQEEISASGTSYLNRTEAANVEKLVTAFLKSGVVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLYKEIEVASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVLSKQPLWNGLLTHYKEHECLVEGPLNNLKQSMVQFQKPRKIYNDRRLFYGGGAGMIGNDNFGSGNPNADRRGSRGRAGGSYLPSGPPNGARPGLHPAGYPIPRVPLSPFPGGPPSQPYAIPTRGPVGAVPHAPQPGNHGFGAGRGTSVGGHLPHQQATQHNVGTIGPSLNFPLDSPNSQPSPGGPLSQPGYGSQAFRDGFSMGGISQDFLADDIKSQGSHDPYNMADFATQASPGGFAVDYATQGAHGAFPGNFMNQNSQGGYSRFSGINDFMSQEYMAHGGQGLFTQAGFIDSSQDDGQQNPYGVNNPNLQSQGLPNSLYSQPFAHYNTQPLNLSGPQQSQPNQSSQNPKHPYNG
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery.  Eliminates the production of nonsense-containing RNAs (ncRNAs).  Required for plant development and adaptation to environmental stresses, including plant defense and response to wounding.
What are the official names of this protein?
Regulator of nonsense transcripts 1 homolog, ATP-dependent helicase UPF1.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Note=Remobilize from the cytoplasm into processing bodies by SMG7.
Protein: SEB1_SCHPO
Sequence: MSGIAEFDGILDSLEHSKTGISGSKILKLTNLSMENVSENAQFVASVYKYAKRAPVTHKLGALYILDSIVRSFQDGAKKNNESFENPVDASFSGGWCKAAEITDSLVADAIQHAPSAHLPKILKLCDIWEKASTFPPEKLESLRSKLKDAMASTEPVSVDSAAAPSQSTNPEGNGGSVGSQAAAPTSRPVENDAASILEALAAFAQKAPVPSAAEESVSTPPQPAVAPSVSAVVPNLPVHPATAINAQSQSGNPLSNPLFQPSNVPQSIPSGPMGMKTGSVNDTQSQQITLMNVLASQNVPPAQIDSIMKAAFPNYNAPFQPAGVGSVPLPAPTSSQSLRLGSLHRSRSPSPRSGRPRRSPSPSHLSIPSTLPPADGVPKPTPDGFPRRFERDPTIPPDSIKVYSRTLFLGGITRSVREPVLRSMFERFGSVQSLILNHNYRHGFLKMFRRDAAEKAQVAMENVPFADTTIRTKWGVGFGPRECSDFSTGISVIPIRLLTDADRTWLVTAEYGGTGGLPITPGIALDEPDIEIGLGISSKAISKRGKDFAMRRDERFRGRKPYRGGPPIHHGERHFDSGNDWHGNPSTVPPPTNPYNPGYPYMDPNYSSGYVSQPPWQPQ
What is the function of this protein?
Involved in the processing of pol II transcripts.
What are the official names of this protein?
Rpb7-binding protein seb1.
What are the subcellular locations of this protein?
Nucleus.
Protein: QUEC_ZYMMO
Sequence: MTANQTKKSVPSFTSDIRQGVSNEGCLVLYSGGQDSATCLAWALEHFDRVETIGFDYGQRHKVELECRENLKQKLIQNFPDWAAHLGEDHMLDLAVLHQVSDCALTRETEIAFGEDGIPNSFVPGRNLLFFTFAATIAYRRGLRHIVGGMCETDYSGYPDCRDDTIKALQVAINLGLERRLVLHTPLMWLDKASTWQMAEEVGGKELVEIIRQESHSCYLGEREILHDWGYGCGHCPACELRAAGWESYQKSRS
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: IF1A_METM5
Sequence: MRGQQAPQQPTRVRTPRENENEVLGVIEQMLGASRVRVRCMDGKLRMGRIPGKLKRKIWVREDDVVIVTPWEVQSDEKCDVIWRYTKGQVDWLNRKGYLEFMR
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: SYR_NAUPA
Sequence: MKQKVAGKFKDHLGELPPLSKPKNKDFGHFAVPIFKYAKMNKQNPQEFAAALCDALGNCEEFEKVEAVSGFVNITLSDSFLNEFANKVLSEKENFAKGSGKERILLEYISANPTGPLHIGHARGAVFGDAIARIGRHIGYDVVTEYYVNDAGRQITLLGLSVYLAAREILGLDVKWPEEYYRGEYIKDLAAEAIKEFGEDYFKAEIDAENFNDDKLNMWAKDKMLNLIKEDIKALNVTPFDNWVSEKELYKHWDEVRAILEKNGALYEKDGKVWLKSSEYKDEKDRVVVREDGRPTYLAGDIIYHWDKFKRNYDRYINIWGADHHGYIARVKAAIKFLGFDPEKLEILLSQMVKLLKGGEPYKMSKRAGNFILVSDVVKDVGADALRFVFLTKKADTHLEFDVDELNRQDSSNPAYYINYAHARIKSIFRNKEMNLEDTVNIQLKDLSKDEKDLVFLALQFPYVLEEAFINREPHRLTNYLYELASEFHSFYNKNKVIGSEKEEVRLKILAVVASIIKLGLSLLGIEAKERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_CITK8
Sequence: MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASTQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSISGIEGTQMAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_ACIET
Sequence: MTIADIKKTTEAKMDQSIAAFKNNLAKIRTGRANPQLLDTIHVEYYGSMVPLSQVANVALLDARTISVQPWEKNMGAKIEKAIRESDLGLNPASMGDLIRVPMPPMSEERRKEMTKLARSEGEGAKVAIRNLRRDANEGVKKLVKDKLASEDDQKRAEADVQKTTDKHIAEIDALVAAKEQEIMAI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_CHLPN
Sequence: MREETVSWSLEDIREIYHTPVFELIHKANAILRSNFLHSELQTCYLISIKTGGCVEDCAYCAQSSRYHTHVTPEPMMKIVDVVERAKRAVELGATRVCLGAAWRNAKDDRYFDRVLAMVKSITDLGAEVCCALGMLSEEQAKKLYDAGLYAYNHNLDSSPEFYETIITTRSYEDRLNTLDVVNKSGISTCCGGIVGMGESEEDRIKLLHVLATRDHIPESVPVNLLWPIDGTPLQDQPPISFWEVLRTIATARVVFPRSMVRLAAGRAFLTVEQQTLCFLAGANSIFYGDKLLTVENNDIDEDAEMIKLLGLIPRPSFGIERGNPCYANNS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CYSP_HEMSP
Sequence: MAKPKFIALALVALSFLSIAQSIPFTEKDLASEDSLWNLYEKWRTHHTVARDLDEKNRRFNVFKENVKFIHEFNQKKDAPYKLALNKFGDMTNQEFRSKYAGSKIQHHRSQRGIQKNTGSFMYENVGSLPAASIDWRAKGAVTGVKDQGQCGSCWAFSTIASVEGINQIKTGELVSLSEQELVDCDTSYNEGCNGGLMDYAFEFIQKNGITTEDSYPYAEQDGTCASNLLNSPVVSIDGHQDVPANNENALMQAVANQPISVSIEASGYGFQFYSEGVFTGRCGTELDHGVAIVGYGATRDGTKYWIVKNSWGEEWGESGYIRMQRGISDKRGKCGIAMEASYPIKTSANPKNSSTRDEL
What are the official names of this protein?
Thiol protease SEN102.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: ISPH_PSESM
Sequence: MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRSRGAIFVEELEQVPDDVIVIFSAHGVSQAVRTEAAGRGLKVFDATCPLVTKVHIEVARYSRDGRECILIGHAGHPEVEGTMGQYDAVNGGAIYLVEDEADVASLEVRNPESLAFVTQTTLSMDDTSRVIDALRKRFPAIGGPRKDDICYATQNRQDAVKQLADECDVVLVVGSPNSSNSNRLRELAERMATPAYLIDGAEDMQKGWFDGVERIGITAGASAPEVLVRGVIQQLQAWGATGADELAGREENITFSMPKELRVKSLL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MRAZ_MYCCT
Sequence: MLFGTYEHCMDAKQRLTLPAKLRNKLSNPIYLTKGFEADLEIWSKDDFLLQIKEHLNKISDQKDIRDLERIIWSNTVEIGIDNLGRIKIPYNLIQSLNIEKDVFILGLGNRLEIWSKNKYNQHKKELLKENS
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AFVE_ASPFN
Sequence: MSACLRWWSRKFDCEKEYAEAYKQYSKTGKPYATRLKNNDHGIVLPLNSTKEWRTLPHDQLSFLHALSEFADLYMHINMTDRTPLQAVHYCNNTKTLSRFNRLMVDATDRALPLIVGKDTESEWKRANAFHTILSLCSTVAMSVLLGPEFSMDTSLIQTIMMYNTAIMPSCAKRTSYPRILRPFVWRLSPLCRAMKSDLTKTKIKLTPEIKHRIDIARSKKGWLEEGPMSLLDGLIETAFEKGCLSRSSDRGDDDQQVALLAEEIIFYHFELSTPVAFFIIFAVYVIMNNKEYSTPLREEISEALKLSGGSFTLDTLNHAPKLASFVKETCRFFRRVMKPIHLESINLSLKPGTIIMAPGRDVHLDPDYYDNPTTFNGYRFYDASRGTCTPHISTTSPTFLTFSHGISACPARVLATQITRTIFIMFLLKFDVELAHEEMPAYGFANGPAYLPNPSVMMRVRPCQKDVLGV
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aflavarin, a bicoumarin that exhibits anti-insectan activity against the fungivorous beetle C. hemipterus (Ref. 2, PubMed:26209694).
What are the official names of this protein?
Cytochrome P450 monooxygenase afvE, Aflavarin synthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SSRP_BDEBA
Sequence: MSENILIVHENKKARFDYTIVETYEAGLQLMGSEVKSLRNKDVQLKDSYISFKGDEAYLQNAHIAEYKASSYNNHVPERHRKLLMHRNELDEIFEALREKGYSCVPLKIYFKNGRAKLQIALVKGKKTHDKREAIKKRDVSDQIRSSLRRSR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: LPXB_HELP2
Sequence: MPTILVSALEASSNVHLEELRHNLPKDYRFIGVFEGKNALYSPREFSVMGFRDVIGRLGFLLKAHKEMVQLAKQADMVLLMDSSSFNIPLAKKIKKQDPHKKIMYYILPQVWAWKKWRAKSLEKYCDFLGAILPFEVGYYQKKAQYVGHPLLDEIKYYKKDIKGETLVFMPGSRKSEIAKMFPLFVKAAQILEQNEGFKRRVLVVPSFFKGLDLKALYGEDIKLFEISYDAHKSLFEAEFAFICSGTATLEAALIGTPFVLAYRAKTMDFLIARMLVNLHYIGLANIFYNALNNETPGLGESQLHPELIQHFLSVEGLLKAYEEMDRERYFKESLRLREYLASGSTRKIANEMAFLLNLT
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: GATA_RHIWR
Sequence: MTAITDLGLAGLRDGFRAGDFSAREIADAFNGAVAGAKALNAFIIETPDHATAAAEAADRARAAGELLPLSGVPLGIKDLFCTAGHQTTAASHMLGGFTPTYESTVTGKLFAAGAGMLGKLNLDQFAMGSSNETSAYGNVVSPWRRNDGGNAPLAPGGSSGGSSSAIAARIVPAATGTDTGGSIRQPAAFTGIAGIKPTYGRCSRFGIVAFASSLDQAGAMAQDVRDSAILLEAMSGFDPKDSTSLDVAVPKWEANLSSDLKGKKVGIPKEYRVDNMPAEIDALWRQGIEWLRDAGAEIVDVSLPHTRYALPTYYIIAPAEASSNLARYDGVRYGLRDLPEGANLQEMYAATRAAGFGPEVKRRILIGTYVLSAGYYDAYYTKAQKVRALIARDFEEAFRQVDVLLTPTAPSAAFALGEKSADPLEMYLNDVFTVPASLAGVPAMSVPAGLDGQGLPLGLQIIGRPLDEQGVLNAGLAIEQRAGFTAKPQNWWAK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.