PharMolix/UniProtQA huggingface dataset:
Protein: YL484_MIMIV
Sequence: MSRYQPRIILNHPEKVVPDDIMEQFFLTIKTGDIDKIRNFVAQNKNKFNIIEKSSKPGGPNKTPIHAVLELDDRIADQETKLTIIKYLDKMGAPMDLPDSDNVWPIHLAAADQDEDIIDYMLKNKVSIDRKDSSNNTPLHYAVYGKQVPCFDKVKVGSIVPPQDIDKLPLNKTLTDTKDYIVELLNNNPQIKNNLIHTVNTIMNIPSMYQATKTEKDLETDIVDIFTEIASNPSYPSQNYANSMSVQQNKLDQLINRMYILINDDLLRGLTNPLKISPNNTGWGPVTPSSSGQPSSIDRILEREHDYVFNELNNKYSSARNTVIDINLASTNKLSRETIPNIMRNINTNYIDRLIFCPDCSNSEYGEKITLTKMLYLLVWSNYKLNYIPDLVRRIMDNMKIMSTPIHSQIVNSNYTAFPLNSNLLVDDDSSLIGYIFSNLLRNKLNPQSQIDLALANVMDQVDPTINAITGGINSCITNQLVPLFTNSDDPNGAVNLFDGVLNSPINNLWSIPEFRSLREDINDLRPAYRDGKISWFQMLFNLIQEIQPNLVTGNTNDVTNNIFIRGRRTPRYILPLTPLPNSTNYGPPPGPPHGTLNNAYTYSEAFRVMDALVQYITSGQINATRYPRVFDQNINDWIPFIDNEFQSDALLQQYPELTFLYKILAVHTQRAIYSVIFNCISILLRNLPVSPEADIVRNYLELIDDAYMYYLLLPSEPNPAEFTQTGTDDTLADLKQHKWDPDNDLVNWFTKYIQRIPTEFIEQLYQLIIQNIDDFNYGNLENIRNHIESSMGDLSNFITPIINNSEFRNSIKKYFGTFNYPASYNGTRIASMQVIPRFNSLIDDIDFEYRFDDYLTLLRNGAITGLTFLTEVYGYFFVDTKKRLQLIDESLVDINAIVADIIANINNETYYYIPQVILPALVKQLITVITNIYAIKDVLSKFTPVKVEFDSLITNSIPEHNQIINLGNDFVSYVQDQLKIIYTNTIDIIKYHNNVIEFLNTHSASQLINATNTATGNNITTTRVFNRNLIPIQIFPSTLSDNPNFTEIETVLRSYSIPEITYYADATDNTDILIDIFDIGSTLNLYHGTISFDRTGIISNSPNVTDNLQINIENDGTVKDIPDPIAGQWLSFDVNHPRGTSYFNAFIAYITRNFQFDKLNGMPSSVFKFLPEYLSFMKQQIIEQVVQFIVDNKDTNAKKIYDELTNLGTQTSYQAIPDVKNYIIIGKLTDDILNKLFEFAIRQSVSSWIYNITSNDPRYRSIIDPLNQTISIINKKDYLRLSLNQINRETISDLLSTNSPYVDYGLAQVETNPNNLSYTNYQNLNKFIYYLYNINYSSDNFQDGNCYYINPTIVSKLIDSYTLEAKNSDGNTPLHLAISMTNPDIVEILLKHGANPFTFRNIRNESPYDLFNDIIRSHLKYDTGNTVSKSIENFYKPFNDLLVSRLLDDKFKNNIIKNITYGIPIELIMYNHMFHLYLENYRYDFTIEMRDSIRRIFQKYFNITDTVYPTDLFEINRDEDLSKILESEFPQNRVKTSVQLLNPKLRDYQKQLAELNNQIINLTKEKRSTINSQQISFINNLIANLEARKSIVQTNISDLEFKQPTSTVDSAMISSFKSSVNSIQNRIGDRSLNLIDFYRLAFGRIGYSQDLYLNIWRLYLEKDILNARSMIFPLLDQVINNHVSLVKENKMTRENKMTRENKQELAVIVDFYSTVKKYIESKKSLPNNLDDNPILQEEHDHIVYLINLILTPTIRNILISQIYQGLAESDLTNTLIADRNVAIRDILNSEYNGHSLDSFIKDILPNLSVKYFTTIYGNQDPNKFITSASDVFQPIIETVKLNRIIQVSDDSILIQNLRDYVIPFFINTYQNFIHHIELSIYAYEKYILNTYQLTKILQIMSNLQIPK
What are the official names of this protein?
Putative ankyrin repeat protein L484.
What are the subcellular locations of this protein?
Virion.
Protein: URK_LACLA
Sequence: MKKTLIIGVTGGSASGKTSVSHAILETFSNERIAMIEHDSYYKDQSHLTFEERTKTNYDHPLAFDTDYLIAQLKELQYGRAVDIPIYDYAKHTRSQETYRQEPVDVLIVEGILVLEDERLRDLMDIKIFVDTDDDVRIIRRIRRDIEERGRTLDSVITQYLDAVKPMYHQFIEPTKRYADVIIPEGVSNTVGVDIITTKIASILND
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA16_CONAA
Sequence: MGMRMMFTVFLLVVLATTVVSFTSYRASDGRNAAAKASDLIALTVRDCCSRPPCRWSHPELCS
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Am1.6.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SBP_SOYBN
Sequence: MGMRTKLSLAIFFFFLLALFSNLAFGKCKETEVEEEDPELVTCKHQCQQQQQYTEGDKRVCLQSCDRYHRMKQEREKQIQEETREKKEEESREREEEQQEQHEEQDENPYIFEEDKDFETRVETEGGRIRVLKKFTEKSKLLQGIENFRLAILEARAHTFVSPRHFDSEVVFFNIKGRAVLGLVSESETEKITLEPGDMIHIPAGTPLYIVNRDENDKLFLAMLHIPVSVSTPGKFEEFFAPGGRDPESVLSAFSWNVLQAALQTPKGKLENVFDQQNEGSIFRISREQVRALAPTKKSSWWPFGGESKPQFNIFSKRPTISNGYGRLTEVGPDDDEKSWLQRLNLMLTFTNITQRSMSTIHYNSHATKIALVIDGRGHLQISCPHMSSRSSHSKHDKSSPSYHRISSDLKPGMVFVVPPGHPFVTIASNKENLLMICFEVNARDNKKFTFAGKDNIVSSLDNVAKELAFNYPSEMVNGVFLLQRFLERKLIGRLYHLPHKDRKESFFFPFELPREERGRRADA
What is the function of this protein?
Plays a role in sucrose transport.
What are the official names of this protein?
Sucrose-binding protein, SBP.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: COBS_SHEB8
Sequence: MSERESWHKEIDLFLVAMGYFTRIPMPKWVEVDSDKLNKASRYFGLVGLLVGLLSAIVFWLTQNWLPAGVSVLLAMLVGVLLTGGFHEDGLADTFDGFGGGWTAEDKLRIMKDSRLGSYGALALILALLLKWQLLVELALYDPVVAGSALIVAHTVSRVVSASIIFSEKYVRDDETSKSKPLSQHQGINELLILIASGVLVLLFLKGLAALSLLLVMIGLRRLIIVIFRRQIGGYTGDTLGAAQQIAEIVCYFVLLVVGNIL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_LIMRJ
Sequence: MLVPKRVKHRKVQRGHMRGEAKGGKTVTFGEFGLQALDSHWISNRQIEAARIAMTRYMKRGGKVWIKIFPQLSYTSKGVGVRMGNGKGAPEGWVAPVKRGKVMFEVGGVSEEVAREALRLAGHKLPVRTKIVQREEVGGQSNEK
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CRGE_MOUSE
Sequence: MGKITFYEDRGFQGRHYECSTDHSNLQPYFSRCNSVRVDSGCWMLYEQPNFAGCQYFLRRGDYPDYQQWMGFSDSVRSCRLIPHSSSHRIKIYEREDYRGQMVEITDDCSHLQDRFHFSDFHSFHVMEGYWVLYEMPNYRGRQYLLRPGEYRRYHDWGAMNARVGSLRRIMDFY
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin E, Gamma-E-crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: INV1_ORYSI
Sequence: MGTRLLALAPWLLLLLLQLAGASHVVHRSLEAEQAPSSVPASIVSPLLRTGYHFQPPMNWINDPNGPLYYKGWYHLFYQYNPKGAVWGNIVWAHSVSQDLINWIALEPAIKPDIPSDQYGCWSGSATILPDGTPAILYTGIDRPNINYQVQNIAFPKNASDPLLREWVKPAYNPVATPEPGMNATQFRDPTTAWYADGHWRMLVGGLKGARRGLAYLYRSRDFKTWVRAKHPLHSALTGMWECPDFFPLQAPGLQAGLDTSVPSSKYVLKNSLDLTRYDYYTVGIYNKVTERYVPDNPAGDYHRLRYDYGNFYASKTFFDPVKHRRILLGWANESDSVTYDKAKGWAGIHAIPRKVWLDPSGKQLLQWPIEELEKLRGKSVSVSDKVVKPGEHFQVTGLGTYQADVEVSLEVSGLEKAEALDPAFGDDAERLCGAKGADVRGGVVFGLWVLASAGLEEKTAVFFRVFKPAGHGAKPVVLMCTDPTKSSLSPDLYKPTFAGFVDTDISSGKISLRSLIDRSVVESFGAGGKTCILSRVYPSMAIGDKAHLYVFNNGEADIKISHLKAWEMKKPLMNGA
What is the function of this protein?
May play a role in sucrose partitioning during seed development and in stress response.
What are the official names of this protein?
Beta-fructofuranosidase, insoluble isoenzyme 1, Cell wall beta-fructosidase 1, Invertase 1, OsCIN1, Sucrose hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Secreted, cell wall. Note=Associated to the cell wall.
Protein: RNFD_SHEB9
Sequence: MAFKIASSPHVTRNLHTSTVMQRVILCLLPGLVVQCAFFGWGTLVQVLLAILVALSCEAAVMKLRNRNIKASLSDNSAMLTAILIGVAIPPLAPWWMIVMGTAFAIVIVKHLYGGLGHNLFNPAMAAYVLLLVSFPVQMTTWIAPSTVALHSPSLVESLQLIFNVGAHVNMEQFRLGIDGMTMATPLDTLKTDLSMGLTTTESLTKAIFDGSTGVGWFWVNLAYLAGGLVLLKLKAIRWHISTGVLLGLFVASSIGFLLSPDTQASPLMHLFSGATMLAAFFIATDPVTAATSPRGRIIFGALIGVLVYIIRTKGGYPDAFAFAVLLANLCAPFIDYYVRPRTYGHSTS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RAD50_DICDI
Sequence: MTSIEKLLVQGIRSFDPREASVIDFYSPLTLIVGQNGAGKTTIIECLKYTCTGEMPPNCSSGQAFIHDTKIAGESEVKAQIKLRFKNPIGKPIVASRSLSLIQKSNKKQEYKQIDASLQSYTSDGQKVSKSFRCSDMDKEIPDLMGVAKPILKHVIFCHQEDSNWPLSESAKLKLKFDEIFSAVKYTKALKSLKDKRKELTTLIKELKLRLETISANIEHCNRIRKELIKAEEIYSNGNKSLEDIKIAIIEKQKTLSTIKIAESKLQELKNEVTVLNARKLEMERVKNQLFNSLTEVYQNETDEELVFMQSEFNRECETMATAEKELLENSEVLLSQKEVINNLIKENSSQKGRLQSLISQQDSILSDRDKQMKELVTRYKMSDFIQIQLPYQKEIVIKFINEITQKFDTLTSGISNYSKTNKQKLNAIQMKINQKRVDSNQFTSSSNEKMSTITLNSKKIQSLDQEIQQHTNSIGEIDTLEKQIQFSQSELSILKSDANLQEIQQSLDNLTTEKLEIEKEIQSLQSSLKLLNLQASSRTRLNIKRKEIQQNQQNINSQLNSQIINSINLILPNEFNNDNNNDDDDDQFRFNIIQRIEPIVPLINKKRLIFTNQLNELKQQFQILQNKKNQIDAQLTSSIEPQLKKKQIELESYEKLINDSKLKQSNLFENVNSNNNNNNNNNNGITVLLFENKINEMKLSLEKLEKSFIVLESEDILYKEYIEKANQDKECSLCKNEMNGNELTSFVHTLETHCNDIPNQLKQLKIEISNSKIQLEKFNKLLPIIVKREELIEKSIPELKESQKNLLEQQLKSNEMVLEKQNQIESLESQSVLYQQVTLVFQYIDQTKQSIQSIESEIQKEEKEIMKQSSDLRTIEEVDKDLEIQQEQLKTIEKEISNFTNKQKNDQIGIFEKERQLISIKNQLTTIKSASGIIDHLRDTKKELQSNNQQLQLEIENLQQSIDQSNNDAKQLENEFQQLEIEFEKKIDAYSKEKNTFSVRLDSINSLQSKILDPSELCKQLNEIQEKNQELESNLSTLSQDYLIGQQHISTIQQNLSSKDITKRAISDNISFRQHKNNVEQIIRQISRKNELIKEMMQSQLEIDSNKLEQEINSLKSKFDQITGQTAVLQSQINSNRQELSKPTYKNIDDVNKDLLIKLQTTETVGKDLDKYYKALDKSLMKYHTLKMDEINRSIKEIWQTTYKGSDIDTIEIRSEESGTANKTINYRVVMIKGDVELDMRGRCSAGQKVLACLVIRLALAENFCSNCGILALDEPTSHLDRANIESFANSLLNIIESRKSQKGFQLIIITHDEEFVQYLSRGNYCDYYWRVTKNANQHSHLERKEIAEL
What is the function of this protein?
Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis.  In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity (By similarity).
What are the official names of this protein?
DNA repair protein RAD50, DNA recombination/repair protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: DDL_POLAQ
Sequence: MSKQEELLIQWGDRVKACLANLDIKSLGRVGVLLGGRSGEREISLMSGNGVLQALLSKGVDAHGFDPGLRNPTELATEKFDRIFISLHGRFGEDGTIQGLLELLELPYTGSGVLASALAIDKIATKQIWISNGLSTPEYEELTAKSDWNAVVKHLGLPLIVKPAHEGSSLGLTKVKSVEELPAAYQLAAGLDKKVIAETCIVGDELTCPLVGQGNSAEALPVIKIIPPQANYDFHNKYFSDETQYLCPTGLTAEINAAVQDLALAAYQTLGCRTWGRADVMLDKKTGKPYLLEMNTSPGMTSHSLVPMAAKAAGVEYADLVLWLLSQTLLQKEGART
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_STACT
Sequence: MHSKNNTILKMIKGEEVTHTPVWFMRQAGRSQPEYRALKEKYSLFEITHQPELCAYVTHLPVDNYQTDAAILYKDIMTPLKPIGVDVEIKSGIGPVISNTIKTVQDVEKLGQIDPKRDVPYVLDTIKLLTEEKLNVPLIGFVGAPFTLASYMIEGGPSKNYHFTKAMMFRDEATWFALMDHLVDMSITYASAQIEAGAELIQIFDSWIGALNAVDFNYYIKPSMERLIKGIKAQHDVPIILFGVNATHLIEEWNNLPIDVLGIDWRTTIKETSDSGVAKTIQGNLDPSLLLAPWDVIQPRLDKILDEGMQHGKHIFNLGHGVFPEVNPDTLKQITAYVHDYTKRK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABG_STAAR
Sequence: MKMTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase FabG, 3-ketoacyl-acyl carrier protein reductase, Beta-Ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RR18_EPIVI
Sequence: MYKFKRSFRRRLSPIGSGNLIYYRNMSLISRFISEQGKILSRRVNRLTLKQQRLITIAIKQARILSLLPFINNEKQFERIESITRVKGFIKK
What are the official names of this protein?
Plastid 30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid.
Protein: MURC_STRGG
Sequence: MAPGIPAAMERPHFIGIGGAGMSGIAKILAQRGAKVAGSDAKESATAESLRALGATVHIGHAAGHLADDASCVVVSSAIRADNPELLRAGELAVPVVHRSDALASLMNGLRAIAVAGTHGKTTTTSMLAVALSSLGLAPSYAIGGDLEGPGTNATHGEGDIFVAEADESDRSFQKYDPEVAIVLNVELDHHANYASMDEIYDSFETFVGKIVPGGTLVVSADQPGAVELTRRVRDLSDLKVVTYGCAEDADVRVHKVTPRGLTSEVTVLLNGKFLTFTVSVPGAHYAHNAVAALAAGVALGIPAHNLASALGSYTGVKRRLQLKGEAAGVQVIDSYAHHPTEMTADLEAMRGAAADARILVVFQPHLFSRTQELGTEMGQALARADASVVLDIYPAREDPIPGITSALIIDAAKEAGAEVTAVHDQADVPAAVAGMAKSGDLVLTMGAGDVTDLGPRILDHLASGR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERRFI_RAT
Sequence: MSTAGVAAQDIRVPLKTGFLHNGQALGNMKTCWGSRNEFEKNFLNIDPITMAYNLNSPAPEHLTTLGCASPSAPGSGHFFAERGPSPKSSLPPLVIPPSESSGQREEDQVLCGFKKLSVNGVCASTPPLTPIQSCSSPFPCAAPCDRSSRPLPPLPISEDPSLDEADCEVEFLTSADTDFLLEDCVPSDFKYDVPGRRSFRGCGQINYAYFDSPTVSVADLSCASDQNRVVPDPNPPPPQSHRRLRRSHSGPAGSFNKPAIRISSCTHRASPSSDEDKPEIPPRVPIPPRPAKPDYRRWSAEVTSNTYSDEDRPPKVPPREPLSRSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSSKALQRQSSEGSAKAPCILPIIENGKKVSSTHYYLLPERPPYLDKYEKYFREAEEANPSTQIQPLPAACGMVSATDKLASRMKMDVGGHGKRKHLSYVVSP
What is the function of this protein?
Negative regulator of EGFR signaling in skin morphogenesis.  Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4.  Inhibits EGFR catalytic activity by interfering with its dimerization.  Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4.  Important for normal keratinocyte proliferation and differentiation.  Plays a role in modulating the response to steroid hormones in the uterus.  Required for normal response to progesterone in the uterus and for fertility.  Mediates epithelial estrogen responses in the uterus by regulating ESR1 levels and activation.  Important for regulation of endometrium cell proliferation.  Important for normal prenatal and perinatal lung development (By similarity).
What are the official names of this protein?
ERBB receptor feedback inhibitor 1, Gene 33 polypeptide, Mitogen-inducible gene 6 protein homolog, MIG-6, Receptor-associated late transducer, RALT.
What is the protein family that this protein belongs to?
Belongs to the MIG6 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Note=Associated with the plasma membrane of basal skin keratinocytes. Translocates into the nucleus of differentiating suprabasal keratinocytes (By similarity).
Protein: FTSB_PSEA6
Sequence: MKVVPILLFVLLAALQYRLWFGKNSIPEYVAMEKSVAEQAEQNTELLQRNNLLKADIQDLKVGLEAVEERARNELGLIKQGETFYRILPSEE
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: SHH_MOUSE
Sequence: MLLLLARCFLVILASSLLVCPGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLRPGDRVLAADDQGRLLYSDFLTFLDRDEGAKKVFYVIETLEPRERLLLTAAHLLFVAPHNDSGPTPGPSALFASRVRPGQRVYVVAERGGDRRLLPAAVHSVTLREEEAGAYAPLTAHGTILINRVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDGGGGGSIPAAQSATEARGAEPTAGIHWYSQLLYHIGTWLLDSETMHPLGMAVKSS
What is the function of this protein?
The dually lipidated sonic hedgehog protein N-product (ShhNp) is a morphogen which is essential for a variety of patterning events during development.  Induces ventral cell fate in the neural tube and somites (PubMed:11430830, PubMed:24863049).  Involved in the patterning of the anterior-posterior axis of the developing limb bud (PubMed:15315762).  Essential for axon guidance (PubMed:12679031).  Binds to the patched (PTCH1) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes (By similarity).  In the absence of SHH, PTCH1 represses the constitutive signaling activity of SMO (By similarity).
What are the official names of this protein?
Sonic hedgehog protein, SHH, HHG-1, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, ShhNC.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
[Sonic hedgehog protein]: Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Co-localizes with HHAT in the ER and Golgi membrane. SUBCELLULAR LOCATION: [Sonic hedgehog protein N-product]: Cell membrane; Lipid-anchor. Note=The dual-lipidated sonic hedgehog protein N-product (ShhNp) is firmly tethered to the cell membrane where it forms multimers (PubMed:24522195). Further solubilization and release from the cell surface seem to be achieved through different mechanisms, including the interaction with DISP1 and SCUBE2, movement by lipoprotein particles, transport by cellular extensions called cytonemes or by the proteolytic removal of both terminal lipidated peptides.
Protein: F16A1_POLNA
Sequence: MSPKISLTRYLVEQQRIDGHIPPELRLLIEVVARACKSISQAVNKGALGDVMGSAGSENVQGEIQKKLDIIANEVLIEANEWGGHLAAMASEEMDDIYVVPNRYPQGEYLLMFDPLDGSSNIDVNVSIGTIFSVLKKSEDDRGVEESDFLQAGNQQVAAGYCVYGPQTTLVLTVGDGVAMFTLDREQGSFVLTEENVTIPDDTQEFAINMSNMRHWDEPVKRYINECLEGKDGPRGKDFNMRWIASMVADVHRILCRGGVFLYPWDKREPEKAGKLRLMYEANPMSWLIEQAGGAATNGKQRILDIQPTKLHERVSVILGSKNEVERLTAYHSGL
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 1, FBPase class 1 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTF_PYCSU
Sequence: QVNFSPGWG
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, PycSu-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_SALRD
Sequence: MATGDRVQVILECTEEPGTSRYHTTKNRKNTSDRLELMKYNPVLQKHTLHREKK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: REDA_DICDI
Sequence: MKSVILKPKNLVLLGAGVTTTYYLYKFFSAPSVSKDEGDKFGFNAPDPAALARAAVKEKKERFVKPSDNVCPILILYGTEYGLSAEVAKKLEESINSKLEGFWARIIDMEEYEIIEFEKEQIVLIITSTYGDGVPPTTARPFFDYLEANRLNLSHIQFSVLALGDRSYPHYCAAGKTLDKQFEEMGAKRFRDRIEVDQEDWTCFDRYIDTVCGLVPTLGGVEKREGQDYLYEKAKLFALSQGKYNKKKPYSSKLLVKRVLTKGDKVGIHLEFELGDSELKYVPGDALAILPDNAASEVSAIISLLKLSPSFKVSTPGWHYQEGEQPNPSQITLTHILTKCFDIHNCKPELLQLLKDNVKNQQEKEKLTNLLAQGTGKSNTQLVEFLENHHLIDILKMFSSARPPIDDLLAQLAKLLPRYYSIASSMSENKLAVSLCVAVVKYDLHGSERVGIASTHMADRMNVGDRVSIFINNNPDFRLPEDPTTPILMVGPGTGIAPFVSFIQERKALGHTGENHLYFGCRRSDEDFLYSKELQQYHNDGLIKLYTAFSRETSQKVYVQNRLLENSQQICDLINAGGHIYICGDAKSMAPQVHETLSLIITKHMSIDEADAQALLHKLEKEKRYQKDVWF
What is the function of this protein?
Probable NADPH oxidoreductase that controls development beyond the mound stage.
What are the official names of this protein?
NADPH oxidoreductase A.
Protein: DIM1A_ARATH
Sequence: MAGGKIRKEKPKASNRAPSNHYQGGISFHKSKGQHILKNPLLVDSIVQKAGIKSTDVILEIGPGTGNLTKKLLEAGKEVIAVELDSRMVLELQRRFQGTPFSNRLKVIQGDVLKTELPRFDICVANIPYQISSPLTFKLLFHPTSFRCAVIMYQREFAMRLVAQPGDNLYCRLSVNTQLYARVSHLLKVGKNNFRPPPKVDSSVVRIEPRRPGPQVNKKEWDGFLRVCFIRKNKTLGSIFKQKSVLSMLEKNFKTLQAVLASLQNNGEPALNTTSMDLGDQSMGMEDDDNEMDDDDMEMDEGEGDGGETSEFKEKVMNVLKEGGFEEKRSSKLSQQEFLYLLSLFNKSGIHFT
What is the function of this protein?
N6-adenine methyltransferase which modifies the AA dinucleotide at the plant nuclear 18S rRNA nucleotides A1785 and A1786 (PubMed:22829145).  Required for generating appropriate patterns of gene expression during root development, including the cell-specific expression of transcriptional regulators involved in root hair and non-hair cells patterning (PubMed:22829145).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase, 18S nuclear rRNA (adenine(1785)-N(6)/adenine(1786)-N(6))-dimethyltransferase, Adenosine dimethyl transferase 1A, Dimethyladenosine transferase 1A.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: KAP2_BOVIN
Sequence: MSHIQIPPGLTELLQGYTVEVLRQRPPDLVDFAVDYFTRLREARSRASTPPAAPPSGSQDFDPGAGLVADAVADSESEDEEDLDVPIPGRFDRRVSVCAETYNPDEEEEDTDPRVIHPKTDQQRCRLQEACKDILLFKNLDPEQLSQVLDAMFERTVKVDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNHGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKVYKDGERIITQGEKADSFYIIESGEVSILIKSKTKVNKDGENQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSMDLIDPGQ
What is the function of this protein?
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.  Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase (By similarity).
What are the official names of this protein?
cAMP-dependent protein kinase type II-alpha regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Colocalizes with PJA2 in the cytoplasm and the cell membrane.
Protein: PKND_MYCTU
Sequence: MSDAVPQVGSQFGPYQLLRLLGRGGMGEVYEAEDTRKHRVVALKLISPQYSDNAVFRARMQREADTAGRLTEPHIVPIHDYGEINGQFFVEMRMIDGTSLRALLKQYGPLTPARAVAIVRQIAAALDAAHANGVTHRDVKPENILVTASDFAYLVDFGIARAASDPGLTQTGTAVGTYNYMAPERFTGDEVTYRADIYALACVLGECLTGAPPYRADSVERLIAAHLMDPAPQPSQLRPGRVPPALDQVIAKGMAKNPAERFMSAGDLAIAAHDALTTSEQHQATTILRRGDNATLLATPADTGLSQSESGIAGAGTGPPTPGAARWSPGDSATVAGPLAADSRGGNWPSQTGHSPAVPNALQASLGHAVPPAGNKRKVWAVVGAAAIVLVAIVAAAGYLVLRPSWSPTQASGQTVLPFTGIDFRLSPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYVADRGNNRVVKLAAGSKTQTVLPFTGLNDPDGVAVDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAGTVYVTEHNTNQVVKLLAGSTTSTVLPFTGLNTPLAVAVDSDRTVYVADRGNDRVVKLTS
What is the function of this protein?
Key microbial factor required for central nervous system tuberculosis.  Required for invasion of host brain endothelia, but not macrophages, lung epithelia or other endothelia.
What are the official names of this protein?
Serine/threonine-protein kinase PknD.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS19_CHLTB
Sequence: MSRSLRKGPFVDHHLLKKVRDMNALEKKTPIKTWSRRSMITPEMIGHTFEVHNGRKFLTVFVSETMVGHKLGEFSPTRMFKSHPVKKG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.