PharMolix/UniProtQA huggingface dataset:
Protein: COBQ_BURVG
Sequence: MIQGTTSDAGKSTLVAGLCRLARRAGARVAPFKPQNMALNSAVTADGGEIGRAQALQALAAGVAPHTDFNPVLLKPTSDRGAQVIIHGAARMNLDARAYHDYKPVAFDAVLESYARLRAGYDTVIVEGAGSPAEINLRDGDIANMGFAERVDCPVVLVADIDRGGVFAHLVGTLACLSDSERARVRGFVINRFRGDIGLLEPGLDWLRAQTGKPVFGVLPYLHGLLLDAEDMLPRQARSAATRDGAGVLRVVVPALPRISNHTDFDPLRAHPQVEFTYWKSGPVPAADLLILPGSKSVQRDLQWLRDAGWDTVIRRHLRYGGKVIGICGGMQMLGRTLDDPLGLEGAPGSVPGLGLFDFDTTLLPHKTLKNVTGQLALPGAPAVRGYEIHMGDTRGPALAAPALQLAADDAAGGSRADGALSADGQLLATYVHGLFDTPAACAALLAWAGLDGGERIDYPALREASIERLADSFAEHLDLRALYAEFR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: CATIP_HUMAN
Sequence: MSSKVYSTGSRAKDHQPSGPECLPLPEANAEAIDFLSSLHKEELQMLFFSETLAMVSDTGEPQGELTIEVQRGKYQEKLGMLTYCLFVHASSRGFLDKMLCGNSLLGYLSEKLELMEQHSQDFIKFLILPMERKMSLLKQDDQLAVTRSIKEGEEVKTGVTSFPWSSIKGFISEAANLVLLRVMAWRRMVPSNARFLTLDTEGKLCYLTYQNLGFQTIQVDHQQAEVFIVEQTVHAEEGIPMSCQYYLLSDGHLAKRIQVGSPGCCIITKMPILREEDEIEPRPVFEKKPLVWEEDMELYSKFLDRKEELRLGHASYLRQHPEAHALISDFLLFLLLRQPEDVVTFAAEFFGPFDPWRPSSPALGSSHRPNPFRSLEPEGDARSGAA
What is the function of this protein?
Plays a role in primary ciliogenesis by modulating actin polymerization.
What are the official names of this protein?
Ciliogenesis-associated TTC17-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the CATIP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton. Note=Colocalized with TTC17 at F-actin rich zones and at dynamic plasma membrane protrusions.
Protein: GAG_MLVDE
Sequence: MGQTITTPLSLTLEHWRDVQCIASNQSVDVKRRRWVTFCSVEWPSFDVGWPLDGTFNLDIILQVKSKVFCPGPHGHPDQVPYIVTWEALAYHPPPWVKPFVSPKPFPLSTLPFSPPGPSAHPPSRSDLYTALIPSIKTKPPKSRVLPTNGGPLIDLLTENPPNLGEQGPPLPKGPVKKRRPPPPRYSPPGPMVSRLRGNRDPPAADSTTSRAFPLRLGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVNSAFPLERPDWDYTTPEGRNHLVLYRQLLLAGLQNAGRSPTNLAKVKGITQGPSESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAEKIFNKRETPEEREERIRRETEEKEERRRAEDEQREKERDRRRHREMSKFLATVVTGQRQDRQGGERRRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLGD
What is the function of this protein?
Involved in the packaging and encapsidation of two copies of the genome.  Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome.  This binding is dependent on genome dimerization.
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p10]: Virion.
Protein: RL7_RICPR
Sequence: MADLAKIEEQLSSLTLMQAAELVKMLEEKWGVSAAAPITVASAGVAAPLAEAVTEKTEFEVVLTATGDKKVEVIKIVKDITGLGLIEAKKLVDEAPKSIKNNVKKAEAEEIKSKLEAAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: UDG_STRPY
Sequence: MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIVSCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIINVLKEQESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFGRD
What is the function of this protein?
Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis.
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: CP17A_CAPHI
Sequence: MWVLLGVFLLTLAYLFWPKTKHSAAKYPRSLPSLPLVGSLLFLPRRGQQHENFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGRPKVATLDILSDNQKGIAFADHGAHWQLHRKLVLNAFALFKDGNLKLEKIINQEANVLCDFLATQHGQSIDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQNVNDGILEVLSKEILLDIFPALKIFPSKAMEKMKGCVETRNELLNEILEKCQENFTSDSITNLLHILMQAKVNADNNNAGPDQDSKLLSNRHMLATIADIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDSIDQNIGFNRTPTISDRNCLVLLEATIREVLRIRPVAPMLIPHKAIIDSSIGDLTIDKGTDVVVNLWALHHNEKEWQQPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDDGKLPSLEGNPSLVLQIKPFKVKIEVRQAWKEAQAEGSTS
What is the function of this protein?
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.  Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways.  A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage.  The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol.  Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione.  Has 16-alpha hydroxylase activity.  Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA.  Also 16-alpha hydroxylates androgens, relevant for estriol synthesis.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Microsome membrane.
Protein: HRH1_GORGO
Sequence: MSLPNSSCLLEDKMCESNKTTMASPQLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINGSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLHCFPLDIVHMQTAAEGSSRDYVAVNQSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSRTDSDTTTETASGKGKLRSGSNTGLGYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRILHIRS
What is the function of this protein?
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
What are the official names of this protein?
Histamine H1 receptor, H1R, HH1R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DSBB_SHEDO
Sequence: MSKLVTFSQQRSAWLILMFSALGLEASALYFQYVMLLDPCVMCIYIRVAVLGLILAGLVGSIAPRFWIVRFLGMSLWGVSSAWGAKLSFELYQMQANPSPFSTCSFYPEFPTWMPLDAWMPSIFMPTGMCSDIPWTMMSLSMTQWTLIAFVGYSIAFLLFIYPGLLYKKPTNPYS
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPH_BIFLO
Sequence: MTADSCNPCLTLENTIDVQEVPMTKSVVLADPRGFCAGVDRAILTVQTILKAAEASGKRTREDGLPPVYVRRQIVHNKHVVEDLAGQGAVFVQELAEIPDAAAQAGIPVVFSAHGVSPVVKAEAERRGMHVVDATCPLVGKVHREVLRFVREGYEIVYIGHKGHDEAVGVVGESPEHVHLIEHESDVDSLDFAPDTKLVLLSQTTLSVDETADTIAALKAKFPWIQEPPSSDICYATSNRQAAVKLVAQQSDCVVIVGSANSSNSVRLMEVAQEGLGERGKAYRVDDASELDPAWFEGLESVGISSGASVPDELVSGVIDALQNLGFTGMKSVETIKENMHFVLPAELRRKK
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: TDA2_YEASL
Sequence: MQIEIKDGRSDNSPLPERKLVTLIQESYDSLKDDNEINLSTESTSNLLIKLVLEKLEKHSSLYKYIASVTTLNIEGLNEENANFSLKNDIGASWESKKDGIFNYKLEDKNSNECYLITILWLHK
What are the official names of this protein?
Topoisomerase I damage affected protein 2.
What is the protein family that this protein belongs to?
Belongs to the TDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Note=Concentrates at cytoplasmic punctate structures and localizes at the mating projection tip.
Protein: YNQ3_STUST
Sequence: MSASKILVGCWLGLAVLSVSTVLLGNAGATLALAAGVLLAAFGKAWLITDGFMELRHAPPAWRLLLLGWPLLMAIGVLLTLL
What are the official names of this protein?
Uncharacterized 8.5 kDa protein in nirQ 3'region, ORF82.
Protein: Y5073_MYCS2
Sequence: MASSAEAIVTHAERSISEDAIVAAARERADDIGAGAVTPAVGALLSVLARLTGGRAVVEVGTGAGVSGLWLLSGMRDDGVLTTIDVEPEHQRIAKQGFSEAGVGPGRTRLISGRAQEVLTRLADESYDLVFIDADPVDQPQFVVEGVRLLRSGGAIVVHRAALGGRAGDADARDAEVTAVREAARLIAEDERLTPVLIPLGDGLLAAVRD
What are the official names of this protein?
Putative O-methyltransferase MSMEG_5073/MSMEI_4947.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: CAPP_NEIMA
Sequence: MQLHILNNPKDAALAADAEFLKQSLFNLLHEEASPLVVETVKLLSTSDDSAALIEKVLPQLDEQQTHDLTLACGLFAQILNIAEDVHHERRRQIHEEAGRGGAEGSLTETVRRLKAGKADGKSVQRQLDNTSVTAVLTAHPTEVQRQTVLNFNRRIRALLPQRERCTNADALARLRREIDTILLGLWQTSETRRHKLSVNDEINNGVSIFPMSFFEALPKLYRKMEHDFQTAYPDVRVPDILKIGGWIGGDRDGNPFVSAETLRFAFRRHADAVFRFYRGELDKLYRELPLSIRRVKVNGDVMALSDKSPDEETARAEEPYRRAIAYIMARAMGKARALGLGMGCKFGFLEPYASAQEFLDDLKKLQHSLIDNGSRLLAEGRLADLIRSVSVFGFHMMPLDLRQHAGKHADVVAELFQHAGLEDYNSLNEEQKQAALLRELSHQRPLYSPFITYSDHTRHELAIFNEARKIKDEFGEDAVTQSIISNCEQPSDLLALALLLKETGLLAVENGKPKSRINIVPLFETIEALENACPVMETMFRLDWYGALLESRGNIQEIMLGYSDSNKDGGYVTSSWCLYQAELGLVELFKKYDVRMRLFHGRGGSVGRGGGPSYQAILAQPAGSVAGQIRITEQGEVITAKYADPGNAQRNLETLVAATLEASILPDKKDPDAKLMQDLSDVSFKYYRELITHPDFIDYFLQTSPIQEIATLNLGSRPASRKTLARIQDLRAIPWVFSWMQNRLMLPAWYGFGSAVETLCEGNPDTLAALREHAQSNPFFQAMLSNMEQVMAKTDITLAENYAGLSESPDKAKVIFGMIKEEYRRSRKALLDLLQTEELLRDNRSLARSLALRIPYLNALNGLQVAMLKRLRKEPDNPHALLMVHLTINGVAQGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: LEXA_LACJO
Sequence: MTEPHANKQLEILRFIYDTVEERAFPPTVREICSAVDLSSTSTVHGHLARLEKKGYILKDATKPRAIEVTEKGREALGIKPKDIPVVGVVTAGQPILAVQDIDEYFPLPPDLENDAGELFMLRVHGESMINAGILNGDHVIVRKQSSANNGEIVVAMTEDNEATVKRFFKEDGYYRLQPENDTMDPIILPVVQILGKVVGLYRNNID
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: APOC2_SAIBB
Sequence: MGTRFLLALFLVLLVLGFEVQGAPLPQQEESAGPALLTQMRESLSGYWDSAKAAASSLYQKTYLPAVDEKLRDMYSKSTAAVSTYAGIFTDQVLSMLRGEE
What is the function of this protein?
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma.  Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.  Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase.
What are the official names of this protein?
Apolipoprotein C-II, Apo-CII, ApoC-II, Apolipoprotein C2.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4658_STRAW
Sequence: MGIEEYGGGQGPHSDVLVVTTNDVPGYRVQHVIGEVFGLTVRSRHLGSQIGAGLKSMIGGELKGLTKTLVETRNQAMERLVEQARVRGGNGILMMRFDVTEAADVGTEVCAYGTAVVLVKA
What are the official names of this protein?
UPF0145 protein SAV_4658.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: ATP6_BRUMB
Sequence: MANDPIHQFQVSRWIPIDVGGVDLSFTNVSAFMVATVVLASGFLYLTSSGRGLIPTRLQSVSEMAYEFVATSLRDSAGSKGMKFFPFVFSLFMFVLVANFIGLFPYFYTVTSQIIVTFALSLLVIGTVIFYGFFKHGFGFLKLFVPSGVPGIIVPLVVLIEIISFLSRPISLSVRLFANMLAGHITLKVFAGFVVSLSSLGALGIGGAVLPLLMTVAITALEFLVAFLQAYVFTVLTCMYINDAVHPGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IBP4_BOVIN
Sequence: MLSLCLMAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCALGKGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLVHGQGVCMELAEIEAIQESLQPSDKDEGDHPNNSFSPCSAHDRKCLQKHLAKIRDRSTSGGKMKVIGAPREEARPVPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSFRE
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.
What are the official names of this protein?
Insulin-like growth factor-binding protein 4, IBP-4, IGF-binding protein 4, IGFBP-4.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1244_SULIA
Sequence: MSYLVVTIKVILITGMPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGERLMDFAKRLREIYGDGVVARLCVEELGTSNHDLVVFDGVRSLAEVEEFKRLLGDSVYIVAVHSPPKIRYKRMIERLRSDDSKEISELIRRDREELKLGIGEVIAMADYIITNDSNYEEFKRRCEEVTDRVLKNG
What are the official names of this protein?
UPF0200 protein M1627_1244.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: ZN605_HUMAN
Sequence: MIQSQISFEDVAVDFTLEEWQLLNPTQKNLYRDVMLENYSNLVFLEVWLDNPKMWLRDNQDNLKSMERGHKYDVFGKIFNSSINIVHVGLRSHKCGTGEKSLKCPFDLLIPKNNCERKKIDELNKKLLFCIKPGRTHGGIKYCDCSTCRKSSNEEPWLTANHITHTGVYLCMECGRFFNKKSQLVIHQRTHTGEKPYQCSECGKAFSQKSLLTVHQRTHSGEKPHGCSECQKAFSRKSLLILHQRIHTGEKPYGCSECGKAFSRKSQLKRHQITHTIEKPYSCSECGKAFSQKLKLITHQRAHTGEKPYPCSHCGKAFFWKSQLITHQRTHTGKKPYGCGECQKAFSRNSLLIRHQRIHTGEKPYECNECGEAFIRKPQLIKHQITHTGEKNYRCSDCEEAFFKKSELIRHQKIHLGEKPYGCIQCGKTFFGKSQLLTHHRTHTGEKPYECSECGKAFTQKSSLISHQRTHTGEKPYECSECRKTFSEKSSLIHHQRTHTGEKPFECSECRKAFAWKPQLLRHQRIHTGEKPYECSECGKAFVQKVQLIKHQRNHTGEKTYGCSDCAKAFFEKAQLIIHQRIHTGERPYKCGECGKSFTRKSHLMRHQRIHTGDKYYGCNECGTTFNRKSQLMIHQRNHII
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 605.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DRS1_ASHGO
Sequence: MGTKKVNQFKDFVPTISDSEEDIPDLDASDDEYETAGKVKSRKKTKKGRKGGAVIADDEDAHADLNPEFHFNDEGAEGTTDFSGWDFVGDGERAEQKDVDLDGIIRRKGGLVQLAGVEESEEEVEEAESAAGASDDEELALDGFGMGAVAQREAAGAADESDSESDKDSDNSAEEAVELDGVEFGDEQEEAREEDTAEEMAQFYAPSNEGEEAKNVVHSTFNSLSLSRPVLKGLAALGYTKPSPIQGATIPIALLGKDVIAGAVTGSGKTAAFMIPIIERLLYKPAKIASTRVLVLTPTRELAIQVADVGKKLGKFVSGLTFGLAVGGLNLRQQEQALKLRPDIVIATPGRIIDHIRNSASFSVDSVEVLVIDEADRMLEDGFQDELNEIMSLIPSKRQTLLFSATMNSRIKQLISLSLKKPVRIMIDPPKQAANKLTQEFVRLRKREHLKPALLYHLLRKLDSTGQKRIVVFVARKEVAHRLRVILGLLGMKAGELHGSLTQEQRLQSVNNFKSLDVPVLVCTDLASRGLDIPKIEVVINYDMPKTYEIYLHRVGRTARAGREGKSVTLVGESTQERSIVKDAIKSVDGSKGSGRACGRVVDWKQVEEIHKLVQAKEDVIGEILEEEKQEKEILRAEMEIRKGENMLKFKEEINARPRRTWFQSESEKKNSSILQALSKNKKVTNSKKRKREEAQQEVGSRQYKKTQKDRTTNQELAFRKQKKGGNKKKKVRK
What is the function of this protein?
ATP-binding RNA helicase involved in ribosome assembly.
What are the official names of this protein?
ATP-dependent RNA helicase DRS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RNH2_BRUSI
Sequence: MKRSASDSPLLFDLPLAPDFSQEQQLMKRGLKHIAGIDEAGRGPLAGPVVAAAVVLDQNDLPEGLDDSKRLTAARREALYEIILTKAITVSVASLSARSIDASDIHKAALEAMRRAVIGLTLKPCHALVDGRDVPPGLPCPGSALVKGDQRSVSIAAASIVAKVTRDRMMIRAGAAHPPYGLEIHAGYATQKHRAAIESEGPVPGLHRYTFAPIKGRFDC
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_PSEA8
Sequence: MTYPERPLLHLLTRTSLVGQIIVGLIAGLLLASFFPAAALKVGFIGKVFVSALKAVAPVLVFVLVMASIANHRQGQQTHIRPILLLYLVGTFSAAVVAVIASFAFPSSLVLASHPGEMSPPGGIAEVLQSLLLSVVDNPVNALISANFIGILAWAIGLGIAFRHASDTTRNLLSELSNGVSLIVKVVIRFAPLGIFGLVASTFAESGVEALKGYAHLLVVLLGCMLFVAFVVNPLIVFLKIRRNPYPLVLTCLRESGMTAFFTRSSAANIPVNLQLCERLGLHEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIAVDVPTAILLSVVASICACGASGVAGGSLLLIPLACSLFGIPSEVAMQVVAVGFIIAILQDSAETALNSSTDVLFTAAACEAEERKASAA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APAG_SHISS
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: SECB_YERE8
Sequence: MSEQNNTEMAFQIQRIYTKDISFEAPNAPQVFQQDWQPEVKLDLDTASSQLAEDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIDGTQLAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAEGEGAEQRQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4981_PSEPK
Sequence: MLKKTFAALALGTALLSAGQAMAAEYKIDKEGQHAFVDWKISHLGYSFIHGTFKDFDGNFSWDSAKPEASKISVDLKTASLWSNHAERDKHIASADFLDVKKYPDAKFVSTSVKSTGDKTADVTGDLTMHGVTKPVTFKATFNGEGKDPWGGERAGFNATTTLNLNDFGIKGPGATSQTLDLDISVEGVKQK
What are the official names of this protein?
UPF0312 protein PP_4981.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y1873_ANOFW
Sequence: MTPEVAINFRERAYSLLQADAEKIVKLIQVQMDHLTMPQCPLYEEVLDTQMFGLSREIDFAVRLGLVDEKDGKAILDRLERELSALHEACTKKKKK
What are the official names of this protein?
UPF0358 protein Aflv_1873.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: PG050_VAR67
Sequence: MSKILTFVKNKIIDLIKNDQIKYSRVITIEESDSLLSVNEVYANHGFDCVEMIDENIINENLEQYKTDSFLQ
What are the official names of this protein?
Protein OPG050, Protein F6.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG050 family.
Protein: SCPB_MYCPN
Sequence: MDATIKVTKPVLKQKDSSAANLVAAIYGLLFVSGEKGLTLAELNRVLRKVGLEKIKAALVQLERKLSLDDESGIEIKKFGHSFRLVTKMEIKDFIHRYLPNKIKNPLNSKTMEVLAIIAYNQPCTRPRINEIRGADSFQIVDDLLEKELIVELGRKDTPGRPFIYEVSPKFYDLFGINSLDELPKVENFDLDKFRQGSFFDSNRYGDD
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: TPIS_PHOV8
Sequence: MRKNIVAGNWKMNKNLQEGIALAKELNEALAADKPNCDVVICTPFIHLASVTPIVDKAVIGVGAENCADKVSGAYTGEVSAEMVASTGAEYVILGHSERRAYYHETVEILEEKVKLALANNLKPIFCIGEVLEEREANKQNEVVAAQLASVFSLSAEDFSKIILAYEPVWAIGTGKTATAEQAQEIHAFIRSLIADKYGKEVADNTSILYGGSCKPSNAKELFANPDVDGGLIGGAALKVVDFKGIIDAFK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM4_HUMAN
Sequence: MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLIFTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCGNAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC
What is the function of this protein?
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins.  Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).
What are the official names of this protein?
Uroporphyrinogen-III synthase, UROIIIS, UROS, Hydroxymethylbilane hydrolyase [cyclizing], Uroporphyrinogen-III cosynthase.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen-III synthase family.
Protein: DER_HAMD5
Sequence: MIPIIALIGRPNVGKSTFFNRLTQTANALVADFPGLTRDRQYGHAEIENHKFIIIDTGGINGIEGIENIQKHMTHQSFLAIEEADVVLFILDARAGLLPADLEIAKHLRKRKKATFLVANKIDGMNSDTALTDFYSLALGKVYGIAASHGRGVAQLMSSVITPFVPEKPIIELSEEELNSSYWEKQKTEVDKTDFLESKKFLCNPESLPIKLAIVGRPNVGKSTLVNHILAQDRMLVYDIPGTTRDSIYIPLIRNNREYIFIDTAGVRKSAKIKEKVERFSVIKTLKAIENANVVLLVIDANEGVSDQDLSLLSFILNSGRSLVITVNKWDAISSEKRKQIKNSLDLRLGFMDFARTHFISALHGSGVENLFKSIKEAYDCSTKRINTSLLTRIMQLAKEEHEPPLVRGRRVKLKYAHSGGYNPLIVVIHGNQVTAINDSYKRYLMNYFRRSLKIIGAPIRIQFKESENPFASKRNTLTPNQVRKRKRLITHLKKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.