PharMolix/UniProtQA huggingface dataset:
Protein: PRPC_ECOLI
Sequence: MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHYRGYDILDLAKHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPAASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERIQPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSDMYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPVYTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNMMGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRPFVALDKRQ
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA.  Also catalyzes the condensation of oxaloacetate with acetyl-CoA to yield citrate but with a lower specificity.
What are the official names of this protein?
2-methylcitrate synthase, 2-MCS, MCS, (2S,3S)-2-methylcitrate synthase, Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: DPS_SERMA
Sequence: MSTAKLVKTKSSDLLYTRNDLDEKVKLAAIKALNHQVVQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTAIIEHQDTFAERVVQLGGVALGTVQVVNDRTPLKSYPTNIHSVQEHLKALADRYGAVANDIRKAITEVEDEDTADMFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_PROM9
Sequence: MPNNFRLAKVSSLLKKEITLILQNDLENDLIRDYFVNISKIDLSGDLQHCKIYITSTAKETVRKEIVANLNTAKSFIRNNLGKRIEMRRVPEIIFKEDIVLDKGLSVLKLLDELKNKHQDKNYEDKDANS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_RHIWR
Sequence: MAKLSKKQKNQAASVDSQKLYGVDEAIALAKQNATSKFDETIEVALNLGVDPRHADQMVRGVVTLPKGTGKDVRVGVFARGAKADEAKAAGAEVVGAEDLLETIQGGTVDFDRCIATPDMMGLVGRLGKILGPKGLMPNPKLGTVTMNVAEAVKAAKGGQVEFRVEKAGIIHSGIGKASFPAEDLRANFDAFVDAIVKAKPTGAKGKYLKKAAVSSTMGPGVKIDVADVAGA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CLPX_LEVBA
Sequence: MFENTETEGPVTCSFCGKTQDQVQKIVAGPGVYICNECIDLCKEIIDEEFNQTAAQETLEVPTPADIVKTLNQYVIGQTEAKRTLSVAVYNHYKRVNEMAQETDDDGPELQKSNIAVIGPTGSGKTYLAQSLAKILNVPFAIADATTLTEAGYVGEDVENILLKLLQNADYDVDRAEKGIIYIDEIDKIAKKAENVSITRDVSGEGVQQALLKILEGTIANVPPQGGRKHPQQEFIQIDTTNILFIVGGAFDGIEGIVKRRLGDQTIGFGADSQEQHVLSSGDSLMQHVIPEDLLEFGLIPEFIGRLPILTALEKLDENDLVRILTEPKNALVKQYEKLLALDNVDLQFQPAALREMAKLAIARNTGARGLRSIIEDVMRDIMFDLPSRTDVAKVVITPETVTEHAEPELVLKDQKAS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ANLN_HUMAN
Sequence: MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVESTSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKAASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPESLVSTPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSEDRDLLYSIDAYRSQRFKETERPSIKQVIVRKEDVTSKLDEKNNAFPCQVNIKQKMQELNNEINMQQTVIYQASQALNCCVDEEHGKGSLEEAEAERLLLIATGKRTLLIDELNKLKNEGPQRKNKASPQSEFMPSKGSVTLSEIRLPLKADFVCSTVQKPDAANYYYLIILKAGAENMVATPLASTSNSLNGDALTFTTTFTLQDVSNDFEINIEVYSLVQKKDPSGLDKKKKTSKSKAITPKRLLTSITTKSNIHSSVMASPGGLSAVRTSNFALVGSYTLSLSSVGNTKFVLDKVPFLSSLEGHIYLKIKCQVNSSVEERGFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQIEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQKLNQVLVDIRLWQPDACYKPIGKP
What is the function of this protein?
Required for cytokinesis (PubMed:16040610).  Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression.  Plays a role in bleb assembly during metaphase and anaphase of mitosis (PubMed:23870127).  May play a significant role in podocyte cell migration (PubMed:24676636).
What are the official names of this protein?
Anillin.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cell projection, bleb. Note=Mainly found in the nucleus during interphase. Colocalizes with cortical F-actin upon nuclear envelope breakdown in mitosis and subsequently concentrates in the area of the prospective contractile ring in anaphase. This pattern persists until telophase, when the protein becomes concentrated in the midbody.
Protein: RS8_ACAM1
Sequence: MAANDTIGDMLTRIRNANLARHQTTQVMSTRMTRSVASVLKDEGFITSFEESGEGVERRLVITLKYRGKNRQPIINTLQRISKPGLRVYSNRRDLPRVLGGIGIAIISTSSGIMTDRDARQTGVGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: YOAH_ESCF3
Sequence: MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRANHSGERIVARFEDEDE
What are the official names of this protein?
UPF0181 protein YoaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: NSG1_HUMAN
Sequence: MVKLGNNFAEKGTKQPLLEDGFDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYEPDRKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDRACPDGFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLSEQETEAAEKSA
What is the function of this protein?
Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway.  Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity).  Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity).  In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage (PubMed:20599942, PubMed:20878061).
What are the official names of this protein?
Neuronal vesicle trafficking-associated protein 1, Neuron-enriched endosomal protein of 21 kDa, Neuron-specific protein family member 1.
What is the protein family that this protein belongs to?
Belongs to the NSG family.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane. Endosome membrane. Cell projection, dendrite. Early endosome membrane. Late endosome membrane. Lysosome lumen. Recycling endosome membrane. Cytoplasmic vesicle membrane. Golgi apparatus, Golgi stack membrane. Endosome, multivesicular body membrane. Endoplasmic reticulum membrane. Note=Endocytosed from the cell surface, thus enters into early endosomes, trafficks to late endosomes and degradates in lysosomes (By similarity). Endoplasmic reticulum targeting is essential for apoptosis (PubMed:20599942). Found in both stationary and motile endosomes. A previous study supports a type I membrane protein topology (By similarity).
Protein: ASP_THECC
Sequence: MKTATAVVLLLFAFTSKSYFFGVANAANSPVLDTDGDELQTGVQYYVLSSISGAGGGGLALGRATGQSCPEIVVQRRSDLDNGTPVIFSNADSKDDVVRVSTDVNIEFVPIRDRLCSTSTVWRLDNYDNSAGKWWVTTDGVKGEPGPNTLCSWFKIEKAGVLGYKFRFCPSVCDSCTTLCSDIGRHSDDDGQIRLALSDNEWAWMFKKASKTIKQVVNAKH
What are the official names of this protein?
21 kDa seed protein.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: KLF1_HUMAN
Sequence: MATAETALPSISTLTALGPFPDTQDDFLKWWRSEEAQDMGPGPPDPTEPPLHVKSEDQPGEEEDDERGADATWDLDLLLTNFSGPEPGGAPQTCALAPSEASGAQYPPPPETLGAYAGGPGLVAGLLGSEDHSGWVRPALRARAPDAFVGPALAPAPAPEPKALALQPVYPGPGAGSSGGYFPRTGLSVPAASGAPYGLLSGYPAMYPAPQYQGHFQLFRGLQGPAPGPATSPSFLSCLGPGTVGTGLGGTAEDPGVIAETAPSKRGRRSWARKRQAAHTCAHPGCGKSYTKSSHLKAHLRTHTGEKPYACTWEGCGWRFARSDELTRHYRKHTGQRPFRCQLCPRAFSRSDHLALHMKRHL
What is the function of this protein?
Transcription regulator of erythrocyte development that probably serves as a general switch factor during erythropoiesis.  Is a dual regulator of fetal-to-adult globin switching.  Binds to the CACCC box in the beta-globin gene promoter and acts as a preferential activator of this gene.  Furthermore, it binds to the BCL11A promoter and activates expression of BCL11A, which in turn represses the HBG1 and HBG2 genes.  This dual activity ensures that, in most adults, fetal hemoglobin levels are low.  Able to activate CD44 and AQP1 promoters.  When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.
What are the official names of this protein?
Krueppel-like factor 1, Erythroid krueppel-like transcription factor, EKLF.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with SUMO1 in nuclear speckles.
Protein: LPAR1_HUMAN
Sequence: MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
What is the function of this protein?
Receptor for lysophosphatidic acid (LPA) (PubMed:9070858, PubMed:19306925, PubMed:25025571, PubMed:26091040).  Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents.  Activates downstream signaling cascades via the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins.  Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels (PubMed:26091040).  Signaling triggers an increase of cytoplasmic Ca(2+) levels (PubMed:19656035, PubMed:19733258, PubMed:26091040).  Activates RALA; this leads to the activation of phospholipase C (PLC) and the formation of inositol 1,4,5-trisphosphate (PubMed:19306925).  Signaling mediates activation of down-stream MAP kinases (By similarity).  Contributes to the regulation of cell shape.  Promotes Rho-dependent reorganization of the actin cytoskeleton in neuronal cells and neurite retraction (PubMed:26091040).  Promotes the activation of Rho and the formation of actin stress fibers (PubMed:26091040).  Promotes formation of lamellipodia at the leading edge of migrating cells via activation of RAC1 (By similarity).  Through its function as lysophosphatidic acid receptor, plays a role in chemotaxis and cell migration, including responses to injury and wounding (PubMed:18066075, PubMed:19656035, PubMed:19733258).  Plays a role in triggering inflammation in response to bacterial lipopolysaccharide (LPS) via its interaction with CD14.  Promotes cell proliferation in response to lysophosphatidic acid.  Required for normal skeleton development.  May play a role in osteoblast differentiation.  Required for normal brain development.  Required for normal proliferation, survival and maturation of newly formed neurons in the adult dentate gyrus.  Plays a role in pain perception and in the initiation of neuropathic pain (By similarity).
What are the official names of this protein?
Lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor Edg-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell surface. Cell membrane; Multi-pass membrane protein. Endosome. Note=Prior to LPA treatment found predominantly at the cell surface. Internalized after LPA treatment. Colocalizes with RALA in endocytic vesicles after LPA treatment.
Protein: C71AJ_AMMMJ
Sequence: MKMLEQNPQYLYFFSLFLVTIFLYKWLTLKKTPLKNLPPSPPQYPIIGNLHQIGPDPQASLRDLAQKYGPLMFLKFGTVPVLVVSSADAAREALKTHDLVFADRPYSSVANKIFYNGKDMVFARYTEYWRQVKSICVTQLLSNKRVNSFHYVREEEVDLLVQNLENSHSKVANLTELLIEVTGNVVCRVSVGSGDKVDSYKILILEIMDMLGYSRSIEDFFPLLGWVDWLTGLRGKVAEAAKGVDTFLEGVLKEHLSTTGSKYNDFVSILLEIQEADAGSSMDNECIKSLIWDMLGAGTETISTALEWTLAALIKNPDAMFKLQNEVREIGKGKSKISEADLVKMNYLQAVMKESMRLYFTAPLLVPREARQDIKFMGYDISSGTQVLINAWAIARDPLLWDKPEEFRPERFLNSPIDYKGFHYEFLPFGAGRRGCPGIQFAMCINELVVANLVHKFNFELPDGKRLEDLDMTAASGITLRKKSPLLVVARPHV
What is the function of this protein?
Involved in linear furanocumarin (psoralen) biosynthesis.  Converts marmesin to psoralen.
What are the official names of this protein?
Psoralen synthase, Cytochrome P450 CYP71AJ1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: MCPB_TRIEQ
Sequence: MVAYRFLTLISLGLGSHCASALQYGYNQVSTHKDSAVVAGAFPAINGTHLQSPAFTSPGTVPRGFSDGTSGPTRDETMEGFMRRLARSNSWMTYHKANFKSEEGRKFPYMYLSASKSSIEKPSSHKLRVWLQGGVHGNEPAGDQSMLALLGDLAANQKWAAKLLEKMDILVLPRYNPDGVFYFQRYLATNFDPNRDHIKLARQQTRDIKELFARFSPHIATDMHEFTAGRAFGPKKDIIYAADALFSSAKNLNIDEGIRQLSEKLFAKRMGKDIEAAGLRWDPYITQGESSSSKLLLREAGTDAKIGRNAMGLSQCVVFLCETRGIGIADQHFERRTLSGLVMVKSILQTAVDNFDEVYNTIERGIRRFTNSRNDIVLTDRSPIMERTFGMLNTTDATLFDYPIDFATTTPAQAVLTRSRPRAYLIPPSWPDIVKRLEVFGVKADKLPYSYVGPVEALNVTSVTFDKEYYEGVVTTTVETKLVERNIRLPAGSYLVKTNQKNAALAFVALEPENIDSFASFGVIPVSTGDQYPIFRLK
What is the function of this protein?
Extracellular metalloprotease that contributes to pathogenicity.
What are the official names of this protein?
Carboxypeptidase 2, Carboxypeptidase M14B, Carboxypeptidase MCPB.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS10_CYAP4
Sequence: MANLQQQKIRIRLKAFDHRLLDTSCEKIVDTAKRTSASAVGPIPLPTRRRIYCVLRSPHVDKDSREHFETRTHRRIIDIYQPSPKTIDALMKLDLPAGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: KCJ10_RAT
Sequence: MTSVAKVYYSQTTQTESRPLVAPGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELGPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVAYHNGKLCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYVADFSLFDQVVKVASPGGLRDSTVRYGDPEKLKLEESLREQAEKEGSALSVRISNV
What is the function of this protein?
May be responsible for potassium buffering action of glial cells in the brain.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Can be blocked by extracellular barium and cesium.  In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules (By similarity).
What are the official names of this protein?
ATP-sensitive inward rectifier potassium channel 10, ATP-sensitive inward rectifier potassium channel KAB-2, BIR10, Brain-specific inwardly rectifying K(+) channel 1, BIRK1, Inward rectifier K(+) channel Kir4.1, Potassium channel, inwardly rectifying subfamily J member 10.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ10 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Basolateral cell membrane. Note=In kidney distal convoluted tubules, located in the basolateral membrane where it colocalizes with KCNJ16.
Protein: ATPB_STRLI
Sequence: MTTTVETATATGRVARVIGPVVDVEFPVDAMPEIYNALHVEVADPAKEGELKTLTLEVAQHLGDGLVRTISMQPTDGLIRQAPVTDTGAAISVPVGDFTKGKVFNTLGEVLNVDEQYTGERWPIHRKAPNFDELESKTEMFETGVKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMIYRVANNHDGVSVFAGVGERTREGNDLIDEMSESGVIDKTALVFGQMDEPPGTRLRVALAGLTMAEYFRDVQKQDVLFFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPNLADEMGLLQERITSTRGHSITSMQAIYVPADDLTDPAPATTFAHLDATTVLSRPISEKGIYPAVDPLDSTSRILDPRYIAAEHYNAAMRVKNILQKYKDLQDIIAILGIDELGEEDKLVVHRARRVERFLSQNTHVAKQFTGVDGSDVPLDESIAAFNAICDGEYDHFPEQAFFMCGGIEDLKNNAKELGVS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FM522_ASPTN
Sequence: MTAAAVFGCTGAVGSQILATLLASDAFSSVATVSRKLPTAESPKLQAIEEGDTSKWGTTIASLSPKPSVVFNAVGTTRAAAGGIQNQWKIDHDLCIEIAKAAKEAGVKTYVFISSGGTRGFLSRHVPYSKMKIGVEDAIKELGFEHAIILRPGMIIGREKSKAPLFEAIVGHLNKLGQGVQDRIGQDQLIIGRAAVAAARLAEDGKAPSKFWAVEMSDIVRLGRDEWKE
What are the official names of this protein?
Protein fmp52-2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP52 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein.
Protein: MRAZ_CERS1
Sequence: MAEAFRGEYNQKVDAKARVSIPAPFRRVIEAGDPKFSGGRSSFVLVYGGDRSYVECYTISEMERIEERIRSLPMGTPKRRYLERNMITLALNMELDEDGRIVLPPKGREKLGISPDELKGGTEATFAGTLNKFQIWKADTYAAELAAEEEVLLPPGADMLSLLEETGL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL5_PSET1
Sequence: MAKLHEVYKDKVVAELQEKFGFSSVMQVPLIEKITLNMGVGEALADKKILDNAVADLAAISGQKPLITKARKSVAGFKVREGYPIGCKVTLRGERMWDFFERLVSIAIPRIRDFRGVSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGMDITITTSAKSDEEGRALLEAFNFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DUS3_ASPCL
Sequence: MDSTPLAQPLVVDTDNKTPKHDLENGASTADTIEEHPAKKPRLENAPVTEKEEADAAPKRVKGIAPVKAEFIVQKSARPQPVEADNTVDADDAAEAASHQQRESEQKGKKKTSGQNKGRDFGQHNDAKGLCPSRAFSPEFSPKECKFGDRCRFEHDVRTYLKEHKRADLTTFGGICPLWEAKGRCPYGYKCRFVGSHMTERETADGRKELVLVEDETRKKAQPLVPHASEDGIVNAVSMEDKVAVARRKIKTPRSDAYLTWLDKTSKALEKNLHGRHFDDDAEGEVGADVKVSLEDVRAAYVEPPFLPSEKRRLYFGPETPALAPLTTQGNLPFRRLCTDLGAQFTYSEMAMGMSLIQGQKSEWALMKAHETEAIPPTISSGANIVQGYDNSQDLKFGAQIAANKPWHAIKATELLGRLTPHLRVIDLNCGCPIDQVYRDGAGSALLDHQSKLEKILRGMNAVSEAIPITVKIRTGTRDASPNALKLIERLTLGGHESSMLNIGPPGVAAITLHGRTRQQRYTKQADWSYIAECAALIKRLNEKTDEVTDTVREPDARTLPNGGKVYFLGNGDCYSHKDYEDHINNAGVDAVMVGRGAIIKPWVFEEIQTGQYLDKTATERLAYVEKFAKYGLDTWGSDEHGVGTTRRFMLEWLSFTQRYVPIGLLDYLPPNIQDRPPAWRGRNELETLLGSPNYKDWIKITEMFLGPAHKDFKFEPKHKSNAYEPQG
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase dus3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COAA_MYCA9
Sequence: MPRLSEPSPYVEFDRKQWRALRKSTPLVLTEEELIGLRGLGEQIDLTEVAEVYLPLARLIHLQVAARQRLFAATATFLGDQHPDRLVPFVIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELSRRNIMHRKGFPESYNRRGLLRFVTEVKSGAREVTAPVYSHLLYDIIKNEKHVVQQPDILILEGLNVLQTGPTLMVSDLFDFSIYVDARIEDIEQWYISRFLAMRSTSFANPSSHFHHYAKLSDKQATLAAQEIWHSINLPNLLENILPTRPRATLVLRKDADHSINRLRLRKL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.