PharMolix/UniProtQA huggingface dataset:
Protein: DGGGP_SACS2
Sequence: MSLKSYMQLVRIHNVIGAALGAIMGFLVSSQWYLELKGILLSALVVGLIAAGGYVINDVYDVEIDKINKPYRPIPSGKISVNKAKALSIALFIIGIALSILLNIYALVIALVTAIGLIYYAKDLKKTGFYGNLLVATTTALSIFYGGLAFFSDNWLLRIIIPTLYAFFLTLIREIVKGIEDYNGDSLNNVKTLATTLGINKSWRIAKILLVLLLIISPLPFFIGFNLIYLILLILVFIPFTILSIIQKETIEGASKARTYLKISAISGIIAFLLGSLPFFKG
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP).  This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.  Cannot use other prenyl donors, i. e.  farnesyl diphosphate (FPP) and phytyl diphosphate.  Moreover, 4-hydroxybenzoate, 1,4-dihydroxy 2-naphthoate, homogentisate, and alpha-glycerophosphate do not function as prenyl acceptor substrates.
What are the official names of this protein?
Digeranylgeranylglyceryl phosphate synthase, DGGGP synthase, DGGGPS, (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase, Geranylgeranylglycerol-phosphate geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAE_BORGP
Sequence: MGRNPLIIGITGRIASGKDAASKIISNKYGFYEISADKLGHLVLHEKKEELVKIFGQKILNTRNEIDRLLIRNLVFNDNKELKKLESISHPIIFNKIKKILIQNQSTKIIINAALLFKINLEKLCDYIIVVKAKAPIIKNRLSYSMPSIDSNIINKILEIQKDIFFKKNIINLKIINIINNKNYAYLEKEIEKKMQEIINYERFE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD1_HAEIN
Sequence: MSSFFVAGTDTNVGKTTAARAMIQALQGQGVQVVGYKPIACCGEESIYPVAQSENTSDYDHFVNADVLTLMHSTKENVSYQDINSYTFSHCAPMLTQDKMRIKLDKINCDLTRLNQTYQSVVVEGSFGLMTPMAEGKSFADWIAQQKMPVVLVVGIKDGCVNHALLTVKVIQQLGVPLLGWIANRINPLLSHYAEIVDLLVEHIDAPLLGKIPYLHKPEEQELGHYLTNIDRLMYMQTEFIK
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD 1, DTB synthetase 1, DTBS 1, Dethiobiotin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1301_ARATH
Sequence: MGLVTVGELKPAFTGKRGFRLNSTIRHASEWPISDVSSDLTVQVGSSSFCLHKFPLVSRSGKIRKLLADPKISNVCLSNAPGGSEAFELAAKFCYGINIEINLLNIAKLRCASHYLEMTEDFSEENLASKTEHFLKETIFPSILNSIIVLHHCETLIPVSEDLNLVNRLIIAVANNACKEQLTSGLLKLDYSFSGTNIEPQTPLDWWGKSLAVLNLDFFQRVISAVKSKGLIQDVISKILISYTNKSLQGLIVRDPKLEKERVLDSEGKKKQRLIVETIVRLLPTQGRRSSVPMAFLSSLLKMVIATSSSASTGSCRSDLERRIGLQLDQAILEDVLIPINLNGTNNTMYDIDSILRIFSIFLNLDEDDEEEEHHHLQFRDETEMIYDFDSPGSPKQSSILKVSKLMDNYLAEIAMDPNLTTSKFIALAELLPDHARIISDGLYRAVDIYLKVHPNIKDSERYRLCKTIDSQKLSQEACSHAAQNERLPVQMAVQVLYFEQIRLRNAMSSSIGPTQFLFNSNCHQFPQRSGSGAGSGAISPRDNYASVRRENRELKLEVARMRMRLTDLEKDHISIKQELVKSNPGTKLFKSFAKKISKLNSLFSFSSLKPSLSGKASSESRFLFQRKRRHSVS
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At1g03010.
What is the protein family that this protein belongs to?
Belongs to the NPH3 family.
Protein: PLSY_PROMS
Sequence: MNILIIFTSYLLGSLPTGFLIGKYLKNIDLRTIGSGSTGATNVLRNVGKWPALFVFIIDVGKGLIAVKIAQYYTDQGLIEVIAGISAISGHIWPIWLRGKGGKAVATGLGMFLALSWKVGLASLGIFLIVLTKTKFVSLSSISAAILLPIFMFFYLGKFIHSYFFISLIVALLVIWKHRTNIKRLIKGEESKINQNQ
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPO22_YEAST
Sequence: MSDHNVNSTFRKTLVELCETATWITSQVYAAKNLEKNDLITVDNKISALYPIAEKYDRSFRTTTVILDEELILKLENAASSLWNSLTIAMKAEKASDKYFNEVFCKCKIFATKLLSIHEALFRTNTNLLRNFKCYISSFKSASEYRFDDLITNTQQHSEKYLQIINENVESFSNEEKTEFKKLTFEFYLVNFQLYLSENDLDTANIYTAKVNITDNSKYMDADLLIELCRMIYNSTVMLKEINNPETQLVDVNIISFLKDVEKYLELPVENLKSHTDYSNLKYSVLIFMANCLVEGHPQASELEQCDHYLSLLQNEYPNKVDPFILAINLTKRRNIVNPAETIEEILMRMIMSVDVISNFQAVIASINDLSKMNTKFSIVCLDYLLINKLNSKNDSKFLGKAICSRFLITTQSKTMNDSEIAESLENFSTQMERIVSEPLTKHAISCIITLLWNTGKKLEKMEKYVVSIRFYKLALKDIISQNYSDRGKIQRALQVVYNKIEDYSNTVRVYQDMDEVDRQSPLCQLLMLQSFLADDKTEEALTCLQKIKSSEDEKSTDALILAVAECKRKTDLSVQGLLMIFDKLQSKSNSQTISSTSSSQTLSILRYTLQMIVKVSEEEPLETFINYLPTVQKLLQKAVEFLKTVKLLNQLPPDVEKEAIYQQSVAVNEIEWFASFSYNVAVKCLVDQSCESISEFPQYCIQFIDLIPVQDFTFPKMYHFTYWRFKATILQLIIAKEKAKQDQHQKDWDIYEKSEELVNSINVMKKSSEFKDGSSLEDRNTLHECFLEALTIHLESALMMPDQTRILDILKKTELYQDSRVDALLIDISSNMEDLPKGVLIEILETVLKRNMGPEVKERELCSWLRILLENAINLNHEVELRILDRVLKILNINQSSLQDTDGVLQTELETIATYCWNIGVNYIIKDNKSNGIVWCKHSMGFANMVNEGLQEQLYSLWESLASSANIDINSIAK
What is the function of this protein?
Involved in chromosome segregation during sporulation.
What are the official names of this protein?
Sporulation-specific protein 22.
What is the protein family that this protein belongs to?
Belongs to the SPO22 family.
Protein: RELCH_XENTR
Sequence: MAAPAAGSGPGGSSGGITGGAGGSLGVVGPSTSTSSVNPFLSDSEEEEDGGEEEEEEEEDDNEEDDEDVSPLNERPAASLASRYLQDEADSTLLPSAGPRLCLQPGEPGRVPLDAVAAQLLRDQLLLTALELHTELLESGRELPRLRDYFSNPGNFERATAAPPGFGGNTTASTGGQLNRAGSISTLDSLDFARYSDDGNRETDERVAENEVPLQERKNYKSSPEIQEPIKPLEKRALNFLVNEYLLKNNNKLTSITFSDENDDQDFELWDDVGLNTPKPPDLLQLYRNLSNHQTVSKDVADIAVGVIEGDLEPIQAVKQIAPDSHISQQAAIIKELEDKIILCNNEKAALLEQIGNLERQIESLQKENSASGVCSAAPPTSDRLQSQTSEESDHYIDIQITDSDAKCEGTEERLPFQQSECEPVCQVSEDIPPSPELAKIRKTTLLSAPPSKAGVHFDKPNRKLSPAFHQALLSFCRMSADSRLGSEVSQIADSENGVMKMLGRCLPHIVPNVLLAKREELIPLILCTACLHPESKERDQLLHILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAESCGDLAPYLPKEIRSSLVLAMLQQMLMEDKADMVREAVIKSLGIIMGYIDDPDKYSQGFELLLTALGDPSERVVSATHQVFLPAYAAWTMELGNLQSHLIPTLLSKIEKLLKEGEHGLDEHKLHMYLSALQSLIPSLFATVLQNAPFTSKAKLQGEVPQIEVTRFPRPVSPLQDVATIIGSREQLAVLLQLYDYQLEHEGTTGWESLLWVVNQLLPQLIEIVGRITVTSTASVHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSTAGNGVLTKATVPIYATGVLTCYNQEEDRKLLVGFLEDVMTMLSLSHAPLDSLKASFVELGTNPAYHELLLTVLWYGVVHTSALVRCTAARMFELLVKGVNETLVAQRVVPALITLSSDPEISVRIATVPAFGTIMETVTQRELLERVKMQLASFLEDPQYQDQHSLQTEIIRTFGRVGPNAEPRFRDDFVLPHLHKLSFVNNQQSVDSKRLDIATHLFEAYSALSCCFISEELMMNHFLPGLRCLRTDMEQLSPEHEVILSSMIKECEQKVENKTVQEPQGSMSIAASLVSEDTKTKFLNKMGQLTTSGAMLANVFQRKK
What is the function of this protein?
May regulate intracellular cholesterol transport.
What are the official names of this protein?
RAB11-binding protein RELCH homolog, LisH domain and HEAT repeat-containing protein KIAA1468, RAB11-binding protein containing LisH, coiled-coil, and HEAT repeats.
What are the subcellular locations of this protein?
Recycling endosome. Golgi apparatus, trans-Golgi network.
Protein: LEPA_VIBC3
Sequence: MKHIRNFSIIAHIDHGKSTLSDRLIQVCGGLSDREMAEQVLDSMDLERERGITIKAQSVTLDYTAKDGQTYQLNFIDTPGHVDFAYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMDLEVVPILNKIDLPAAEPERVAEEIEDIVGIDAIDAVRCSAKTGVGVDEVLEKIVSAIPAPQGDPDAPLQALIIDSWFDNYLGVVSLVRIKNGSLKKNDKIKVMSTGQTWGVDRLGIFTPKQVDTDSLDTGEVGWVVCGIKDIMGAPVGDTLTLAKNGCEKALPGFKKVKPQVYAGLFPVSSDDYDNFRDALGKLSLNDASLFYEPETSAALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPTVVYEVLKTNKEIVYVDSPAKLPAINDIEEIREPIARCNILVPADYLGNVITLCIEKRGTQVDMVYHGNQVALTYDIPMAEVVLDFFDRLKSTSRGYASLDYGFQRFEMSHMVRVDVLLNGDKVDALAIITHRDNSQTRGRQLVEKMKEFIPRQMFDIAIQAAIGNHIIARSTVKQLRKNVLAKCYGGDVSRKKKLLKKQKEGKKRMKQIGNVELPQEAFLAILHVGKD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MYOC_FELCA
Sequence: MPATQLLLLACLVWGLGARTAQLRKANDRSGRCQYTFSVASPNESSCPEQGQAMSAIQDLQRDSSAQRADLESTKARLRSLESLVHQLTLDEAAGPSATQEGLQRELGALRREREQLESQNRELEASYSNLLRDKSALEEEKRRLREENEDLARRLDSSSQEVARLRRGQCPQARGTPQDVPSGSREVSKWNVETVNFQELKSELTEVPASRILKESPSGHPRSEEGDPGCGELVWVGEPLTLRRAETITGKYGVWMRDPKPAYPYTQETTWRIDTVGTDIRQVFEYDLSSQFLQGYPSKVHVLPRPLESTGAVVYWGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDETGLWVIYSTQEAKGAIVLSKLNPESLELERTWETNIRKQSVANAFIICGRLYTVSSYSAPDATINFAYDTGTGRSRALTVPFKNRYKYSSMVDYNPLEKKLFAWDNFNMVTYDLRLSEM
What is the function of this protein?
Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration.  Promotes substrate adhesion, spreading and formation of focal contacts.  Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction.  Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways.  Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling.  Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling.  Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling.  Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex.  Involved in positive regulation of mitochondrial depolarization.  Plays a role in neurite outgrowth.  May participate in the obstruction of fluid outflow in the trabecular meshwork.
What are the official names of this protein?
Myocilin.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Cytoplasmic vesicle. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Secreted, extracellular exosome. Mitochondrion. Mitochondrion intermembrane space. Mitochondrion inner membrane. Mitochondrion outer membrane. Rough endoplasmic reticulum. Cell projection. Cell projection, cilium. Note=Located preferentially in the ciliary rootlet and basal body of the connecting cilium of photoreceptor cells, and in the rough endoplasmic reticulum. It is only imported to mitochondria in the trabecular meshwork. Localizes to the Golgi apparatus in Schlemm's canal endothelial cells. Appears in the extracellular space of trabecular meshwork cells by an unconventional mechanism, likely associated with exosome-like vesicles. Localizes in trabecular meshwork extracellular matrix. SUBCELLULAR LOCATION: [Myocilin, C-terminal fragment]: Secreted. SUBCELLULAR LOCATION: [Myocilin, N-terminal fragment]: Endoplasmic reticulum. Note=Remains retained in the endoplasmic reticulum.
Protein: NPS3A_PONAB
Sequence: MLLLRSALTRALASRTLAPQVCSSFATGPRQYDGIFYEFRSYYLKPSKMNEFLENFKKNAHLRTAHSELVGYWSVEFGGRMNTVFHIWKYDNFAHRTEVRKALAKDKEWQEQFLIPNLALIDKQESEITYLVPWCKLEKPPKEGVYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKLVGVFHTEYGALNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPTSFSPLK
What are the official names of this protein?
Protein NipSnap homolog 3A, NipSnap3A.
What is the protein family that this protein belongs to?
Belongs to the NipSnap family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=May be part of some vesicular structure distinct from lysosomal vesicles.
Protein: RL3_STACT
Sequence: MTKGILGRKIGMTQVFGENGDLIPVTVVEAGQNVVLQKKTEEVDGYNAIQVGFEDKQAYKKDSKSNKYANKPAEGHAKKAGTAPKRFIREFKNINVDEYEVGQEVSVDTFEAGDIIDVTGVSKGKGFQGNIKRHGHARGPMAHGSHFHRAPGSVGMASDASKVFKGHKMPGRMGGNTVTVQNLEVVQIDAENNVILVKGNVPGPKKGLVEIKTSIKKGNK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DNAJ_SHIDS
Sequence: MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEVGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNEKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMP3_SCHPO
Sequence: MFKNRKYAIIYTFLLILRFWFSQGSSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIRSVVPLNVMLLPIFLLCRCICKSNCSPYPILLFTRLYMCLISLLIDLSIWNIVPLNARWSALLLYSSSFMATTFQTHTFTNSIETIFFFLTILFLSKLNSVPLNKKISYLYTFLLAIVSVLGFFTRITFLAFVIAPYIYFSVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACILEDYKFYGVFVITFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPLLCGPLIFVPKLWDVRKPATWLWLLPVFILSLFPHQEPRFLLPAASIFIVNSGCLVRSYWIKFLFVMYAVVLAVFFGIMHQNGVIPAVLEVKNIIEQRNVTTMENCNLYFNPEMPTTIYFWKIYSAPTWMLARPKFSQINTSHLYNYSTKQMISKFWETYYEEVKVVNLPEENTTEFQASTLLVCPVAMLQTSSYLQNLTMLHYIPYHVDLDDTDELPLAELIMNHGIGIFTAKEICENNTITNELPTVLRSVG
What is the function of this protein?
Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly.  The presence of a fourth mannose in GPI is essential in fungi (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 4, GPI mannosyltransferase IV, GPI-MT-IV.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NIFH1_RHOCB
Sequence: MGKLRQIAFYGKGGIGKSTTSQNTLAALVEMGQKILIVGCDPKADSTRLILNTKLQDTVLHLAAEAGSVEDLEVEDVVKIGYKGIKCTEAGGPEPGVGCAGRGVITAINFLEENGAYDDVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMALYAANNIAKGILKYANSGGVRLGGLICNERKTDRELELAEALAAKLGCKMIHFVPRNNVVQHAELRRETVIQYDPTCSQAQEYRELARKIHENSGKGVIPTPITMEELEEMLMDFGIMQSEEDREKQIAEMEAAMKA
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein 1, Nitrogenase Fe protein 1, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RECA_STRPD
Sequence: MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPQLFDEIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_AERS4
Sequence: MTPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQAKLGELEFIVVDTGGIDGTEEGIELKMAEQSLLAIEEADVVLFMVDARAGLTAADQAIAAHLRKTHKKVFLVANKTDGIDGDSAVSEFYCLALGDVYQIAAAHGRGVLSLLELALAPHLETLVDAAAEEDAQDEEEEDFDEEALLRMVAAGDLDTREDTKETPFADLPIKFAIVGRPNVGKSTLTNRMLGEDRVIVYDMPGTTRDSVYVPMERDEQKYVVIDTAGVRRRGKVHETVEKFSVIKTLKAIEDANVCLLVIDAQETITDQDLSILGFVLHSGRSVVLVVNKWDGLDQKVKEDVKNELDRRLGFIDFARVHFISALHGSGVGHLFESIQEAYQSATRRTSTAMLTRIMQMAQEDHQPPMVNGRRVKLKYAHAGGYNPPRIVIHGNQLNDLPDSYKRYLINYFRKSLKIMGSPIRVEFQESANPFEGRKNTMTLSQERQRKRLLKAKTKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TSA4_GIAIN
Sequence: MFGRFLLAIVILQLARTACTQEADDGKCKTCGVTIGQDTWCSECNGANYAPVNGQCVDVNAEGPSKTLCPQHSAGKCTQCGGNSFMYKDGCYSSGEGLPGHSLCLSSDGDGVCTEAAPGYFAPVGAANTEQSVIACGDTTGVTIAAGGNTYKGIADCAECSAPDATAGAEAGKVATCTKCGVSKYLKDNVCVDKAQCNSGSTNKFVAVDDSENGNKCVSCSDNLNGGVANCDTCSYDEQSKKIKCTKCTDNNYLKTTSEGTSCVQKDQCKDGFFPKDDSSAGNKCLPCNDSTDGIANCATCALVSGRSGAALVTCSACTDGYKPSADKTTCEAVSNCKTPGCKACSNEGKENEVCTDCDGSTYLTPTSQCIDSCAKIGNYYGATEGAKKLCKECTAANCKTCDDQGQCQACNDGFYKNGDACSPCHESCKTCSAGTASDCTECPTGKALRYGDDGTKGTCGEGCTTGTGAGACKTCGLTIDGASYCSECATTTEYPQNGVCAPKASRATPTCNDSPIQNGVCGTCADNYFKMNGGCYETVKYPGKTVCISAPNGGTCQKAADGYKLDSGTLTVCSEGCKECASSTDCTTCLDGYVKSASACTKCDASCETCNGAATTCKACATGYYKTASGEGACTSCESDSNGVTGIKGCLNCAPPPNNKGSVLCYLIKDSGSTNKSGLSTGAIAGISVAVIVVVGGLIGFLCWWFLCRGKA
What are the official names of this protein?
Major surface-labeled trophozoite antigen 417.
What is the protein family that this protein belongs to?
Belongs to the Giardia variant surface protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PNP_SYNWW
Sequence: MIVKKYQMEVAGRPLIVEIGQVAQQANGAALMRYGDTVVLVTATAAKQPREGIDFFPLTVDYEEKQYAVGKIPGGFIKREGRATAQATLSARLIDRPIRPLFPKGFRNEIHVVATILSVEKDNAPDVTAITGASVALSISDIPFAGPVAAVIVGLVDGELIINPTVEQHQKSDLHLAVAGTKEAIMMVEGGANEVPEETMRDAIFFAHEEIKKIVDFQENIIREVGLSKMQVEIPILDEEIKKAVVEFATPLFEEAVKNPDKKTREDQMDSSQKSVLQHFTESYPEEEKLIADVSDETMKAVVRKMALEEGERVDGRKLDEIRKVSCEVGFLPRPHGSGLFTRGQTQVLSVTTLGAISEEQRLDGLGIEEKKRYIHHYNFPPYSTGETKPMRGPGRREIGHGALAERALLAVIPSEEEFPYTIRVVSEVLESNGSSSMGSVCGSTLSLMHAGVPIKAPVSGIAMGLVKEGERFAIMSDIQGIEDALGDMDFKLAGTEKGVTALQMDIKITGVNREIVEAALKQAREGRMFILKKMLEAIDKPNEELSPYAPQMIRMQIDPDKIREVIGPGGKTIHKIVDETGCKIDIEDDGSLFIMATDEEAAKKARFFVESIVAEVEVGKTYMGTVKRIMDFGAFVEIIPGVLGTSGKEGLVHISQLAEERVNKVRDVVDIGDQILVKVTEIDRQGRVNLSRKAVLKSAVKK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_CHLPD
Sequence: MSEIYRFGVSLDKSLIEAFDRHIQSRHYHNRSEALRDLIREELVRKKWTEGGTVAGAVIMTYDHHKRELVNRLLDIQHDFQKTIIASSHVHLDHDHCLEVIAVKGNAADVEQLSLKLKSLVGVKHLSLSISSAE
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: LEC2_DABRR
Sequence: NQDCRPGWSFYEQNCYKVF
What are the official names of this protein?
C-type lectin domain-containing protein 2, CLP2.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR9_YERPA
Sequence: MQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSILAAYERAYQTDPTSAFGGIIAFNRELDAATASAIISRQFVEVIIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAADLRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHSIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CA198_MOUSE
Sequence: MASMAAAIAASRSAVMSGNRPLDDRERKRFTYFSSLSPMARKIMQDKEKIREKYGPEWARLPPAQQDEIIDRCLVGPRAPAAAADAGDVRDPARFPGLRGPTGQKLVRFGDEDITWQDEHSAPFSWETRSQMEFSISSLSIQEPSAATVTSDARSLAKAPQGTQGSKPAQSSRSSSLDALGPARKEEEAPFWKINAERSREGPEAEFQSLTPSQIKSMEKGEKVLPACYRQEPTTKDREAKPVPQEQQTLPSVSAEQEVPQPVQAPASLLPKATPTESPEKPPPPAVQRDEDDDALFSEPALAQISSSNVLLKTGFDFLDNW
What are the official names of this protein?
Uncharacterized protein C1orf198 homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SHIDS
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSSSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.