PharMolix/UniProtQA huggingface dataset:
Protein: NAA25_ANOGA
Sequence: MQQEDLAYERKLRPIWESIEIGNYKKALQDVEKMLKKKPTLQCARALKAWAYQRLGRTEDSAPLIAALEEEQPIEATTLHALTLYYKETQRLDKICTLFSNAVRQVPGSEELLSQLFIAYMRIDDFKALQSVALQLYKLRPRNSYYFWAVMSVVLQALRGPDAHNAQKAQLLLVLAQRMVDKFIAENKLEGAQEAQLYLQILQEQHKYSEAYDFLQGALCQKLYPGAPVYLRIDLLKQLNKWGELNRLLKELLLQEQDRWDYYQDYINSTFELIRAGEKPDGADYTVEMCHEFLCDIIEAQPKKFRGPYLARLELNRRMVEQRYAAEQLFGKMSDMLAEYFELFADKPCCALDMKLFLEFVKPAHERRTLATKLMNGLGLSSATLPASKEQMQRHICTLQIARYSGAHAIVSEELLHAIYTSLSLHYEHGYNAYGQGLLVTDMGPSDAYALLAAQIMYERAYRMQRSEPAIEALCLLNHLLGNSVNNFHGKLLALQLYHRLGLTQAAQSAYETLDIKHIQLDSLGYLHCAQLANAGFPALAKATYEQTLYFFLNDIDANSEFPKALYNFGTFSKLVEIVDFRSRLANSYHFMLVTVETLLLMVVSSGGTLSQLLAAYRQTRRKPAEDRIRWDKLHDNRDLTIFVSWDPPSDEEEQEEKKDKPMDNGTGGEKEAPVVAAVTKPVGATLEERRERLQKRSYEQDYDLLRLRTGLSKMLFSLVELHLSRTSVECSAAQQLRDDWVTVAADIRSKQHAPISGRYLVNLLPSRLHLYLSLPYERVFTQLADFVLDLWKGYSIEQLTLAADKCSGDVTAIHETMKRAIETYHQSADLLWHWKMTHELVNGCIEMISLMVFLLAVCYDKYLHAPTSQAQPSAGKKVKKGPENSAPNTATTTNASNDASSVVPERERLVLVTKVLRELKQTINAMDLLLASWKPPLVEDSLSAAIERMSLNPKCASTVQSTIAENALTEVRDLRKLLKDKLKLMSKAI
What is the function of this protein?
Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of proteins beginning with Met-Asp or Met-Glu (By similarity).  Has 2 roles in the larval immune response: required both for the phagocytic degradation of internalized bacteria and for the induction of Defensin in the fat body.  Within the phagocytic blood cells, has a role in detection of infection and activation of the humoral immune response (By similarity).
What are the official names of this protein?
Phagocyte signaling-impaired protein, N-terminal acetyltransferase B complex subunit MDM20 homolog, N-terminal acetyltransferase B complex subunit NAA25 homolog.
What is the protein family that this protein belongs to?
Belongs to the MDM20/NAA25 family.
What are the subcellular locations of this protein?
Lysosome. Note=Blood cell lysosomes.
Protein: GRE1_YEAST
Sequence: MSNLLNKFADKLHGNDHDERYEDDNDDQTRQQRHEKHQQREFRNQGSKADPYGEENQGNFPQRQQPQSNLGGNTQFGGNDFQQQTTDYTAGTGGGTYTQTYRETNTQGQLDDDEDDDFLTSGQQQKQGRTRGAQSNRYQSSNIGSGRRDLSGSGNDEYDDDSGNQGVW
What are the official names of this protein?
Protein GRE1, Genes de respuesta a estres protein 1, Hydrophilin.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPH_STAA8
Sequence: MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKPFYEAYGSQFEDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQASEVQDTKKEIVAALRKLND
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: YCB1_SINSX
Sequence: MSLTETIEKKLIEAFHPERLEVINESHQHTGHQPGFDGTGESHMRVRIVSSAFAGMSRVARHRAINDLLKPELDAGLHALAVEPAAPGEPTRW
What are the official names of this protein?
Uncharacterized protein in cobS 5'region, ORF1.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
Protein: Y6560_BRADU
Sequence: MLGWVVTFLVIALIAGILGFGGIAGASIEIAKIIFFIAVVLFLVSAVVGLARGRTRI
What are the official names of this protein?
UPF0391 membrane protein bsl6560.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROC_OLEA2
Sequence: MSGSTFGRVFRLTTYGESHGAGLGGVVDGCPAGIALTEAMIQAELDRRRPGQGGPAATARKEPDRVRLLSGVFEGRTTGTPVAFHVENTDQRSRDYGDIMHVYRPGHADVTYDAKYGRRDYRGGGRSSGRETLSRVAGGAVAQALLAECGITVNAFTVELGGVPARPEDPAGAQDRPFFAPEEDIVAQWDALVRNVKGRGDTVGGIVQVEAYGVPAGLGEPVFDRLDARLACALMSVGAVKGVEIGAGFAAARLTGSSNNDAMTARGYAGNNAGGILGGISSGQTVVARAAVKPIPSVAQEQHTVDDSGREVILRVGGRHDISAIPRIVPVLKAMTALTLADMLLMQRRMTAVRA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: KDPC_POLNA
Sequence: MKNILRPALVLFFVLTLLTGVAYPLAVTGAAQLLFPAQAAGSLILRDGKPVGSSLIGQNFTDPGHFWGRPSATGPMPYNASASGGSNLGPLNPALLDAVKGRIDALRAADPGNAAAVPVDLVTASASGLDPHISPAAASYQAARVARVRGLPLEKVRQLVAQETETPWLGLLGEARVHVLKLNLALDALKPVNAPG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: KTHY_ACTP7
Sequence: MRGKFIVLEGLEGAGKTTAHQVILAQLEKAGKNVVQTREPGGTPLAEKLRHLIKHETEEAVSDKAELLMLYAARIQLVENVIKPALAEGKWVLGDRHDMSSQAYQGGGRQIDRHLLETLKETVLGNFEPDLTIYLDIDPAVGLARARGRGELDRIEQQSLDFFYRTRQRYLELTQNNEKAVIINAEQSIEQVAADIQQAVENFLKIAK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PDXS_STAAC
Sequence: MSKIIGSDRVKRGMAEMQKGGVIMDVVNAEQARIAEEAGAVAVMALERVPSDIRAAGGVARMANPKIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADEEYHLRKDQFTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNSEVSRLTVMNDDEIMTFAKDIGAPYEILKQIKDNGRLPVVNFAAGGVATPQDAALMMELGADGVFVGSGIFKSEDPEKFAKAIVQATTHYQDYELIGRLASELGTAMKGLDINQLSLEERMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: Y1636_STRPQ
Sequence: MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGKQSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNLHAGGSAQMAAFQLMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAHVTALASRPKLIGGARADYNMDIIRKS
What are the official names of this protein?
UPF0340 protein SPs0230.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: GLGA_CLOAB
Sequence: MKILFASSESYPFIKTGGLGDVSYALPKALRKIGIDARVIIPKYSDIPEYFRYNTHHIASFGVPVGWRSQYGGLEYYEYDGVPFYFIDNDYYFKRSGLYGYYDDGERFAYFSRGVLQAITYMQDFNPDIIQCNDWQTAIIPVLLKDHYRNYRNYNHIKTIFTIHNLKYQGVFGKSVLGELLCLNEGYYNENALKFYDGISFMKGGILFSDKLSTVSRTYAEEIKDPYYGEHLDGLLRSRSYDLWGIVNGIDYDILNPETDKDLFFNFDSSTLYNKTKNKIELQKMLNLPVSENIPMIGIVSRLVSQKGLDLISCVLEDLLQDGIQLVVLGTGDAKYENMFKYFAWKYPNKLSANIQFNNSLAQKIYGASDMFLMPSKFEPCGIGQLIALRYGSLPIVRETGGLKDTVRPFNPITGEGNGFSFTNYNAHDMLHVIRNAEYFYYNEKYNWNKLVQTAMNDDNSWSKSAEIYRNLYMSVL
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RS6_STAA9
Sequence: MRTYEVMYIVRPNIEEDAKKALVERFNGILATEGAEVLEAKDWGKRRLAYEINDFKDGFYNIVRVKSDNNKATDEFQRLAKISDDIIRYMVIREDEDK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: EXOC4_DROME
Sequence: MDAPPPTKPPRGVKYGKDESAGCGFLVNVIKSLGFSETTEERQKEKQKIEAEFKRSDLRLNELVSRHDQQLTQVLPLFSQVSSEVTASRERIHAVKENLGVCKRLLQCRRDELRKMWMDAVQHKYVLEMLEQIQELRKVPQRVVGYTAKRQYLHASKALTDALTTLNGPLQAVEGLSDLRTDLQTRRQQLYQRLHEELVTQVYTNSANEALSSFQRTNSSRLNSSFTRGIGARRSTDRIEANARVRKALAEMAQSFDLDKAEVIEDADLIYPELSMSYFVAIIVESFGMLHKVPDSLETLRVQIQTELLNVVRHTTHQLSVSGATADTNPLLSLLEVIFKQFKAIAKTHSLLLKNYLSVGQKYSVVGPQPYDLTDFWAQAQSVLQLLLTDYLDIQNAAADESAQTGFSEPTSNINSYFLRRKVPSTKRSMFKFDKSSHVGTSNNSDAFKEHRRNASDASVDDNLAGQLGGSGKGSTSGLFPHEKKQREKILICTPDQSIITKVYLPLMGYIKEIENFMKCKPGQPCSLHDFLDNYIKDTFLTKGHNRNLQLTIESLSKNQDAWRTIISPEEIKALNLSRPLLQSTVMVERRLMETKNLIQDLPCYSEDLLKMVCALLKAYREICQAAYRGIVQPDSEDKRIYSVAWLKDEDISRFLKTLPNWTDLKTYSQKSRHNRKLHRGSFEPSEEESPLQVQQRNIREAEMLTSNLGEGGITQQEILVEISVLKELAILQESMEWFSCRVSEFANDLRRPLVNGLNAVPAECGADIAVKDGTIKVMTNLALEFDELANTCLLVLHLEVRVQCFHYLRSKSSVRTNSYVGSKDDILEPDRQVQVLTKRLSEMDEAFSATLHPRKTRYIFEGLAHLASRILIQASNYLEHIDQITVQRMCRNAIALQQTLSNITASREVALDQARHFYELLCMEPDEILNALLERGTQFSEMQLLNALQLSCKSFGITDANLLASYQQKLSDILGAKPSKGVVV
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.  Involved in regulation of synaptic microtubule formation, and also regulation of synaptic growth and glutamate receptor trafficking.  Does not appear to be required for basal neurotransmission.
What are the official names of this protein?
Exocyst complex component 4, Exocyst complex component Sec8.
What is the protein family that this protein belongs to?
Belongs to the SEC8 family.
Protein: SCTC_RALSO
Sequence: MAAALLLWTAGTVCAAPIPWQSQKFEYVADRKDIKEVLRDLGASQHVMTSISTQVEGSVTGSFNETPQKFLDRMAGTFGFAWYYDGAVLRVTSANEAQSATIALTRASTAQVKRALTRMGIADSRFPIQYDDDSGSIVVSGPPRLVELVRDIAQVIDRGREDANRTVVRAFPLRYAWATDHRVTVNGQSVNIRGVASILNSMYGGDGPSDSGTAPRAQDRRLDSVAPGEASAGRAGTRALSSLGGGKSPLPPGGTGQYVGNSGPYAPPPSGENRLRSDELDDRGSTPIIRADPRSNSVLVRDRADRMAAHQSLIESLDSRPAVLEISASIIDISENALEQLGVDWRLHNSRFDLQTGNGTNTMLNNPGSLDSVATTAGAAAAIAATPAGGVLSAVIGGGSRYLMARISALQQTDQARITANPKVATLDNTEAVMDNRQNFYVPVAGYQSADLYAISAGVSLRVLPMVVMDGGTVRIRMNVHIEDGQITSQQVGNLPITSQSEIDTQALINEGDSLLIAGYSVEQQSKSVDAVPGLSKIPLVGALFRTDQTTGKRFQRMFLVTPRVITP
What is the function of this protein?
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells.  Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
What are the official names of this protein?
Type 3 secretion system secretin, T3SS secretin, Hypersensitivity response secretion protein HrpA.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. T3SS SctC subfamily.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ARKA_DICDI
Sequence: MSIKLPLSNINSGGNSNNSSSSNSTSNNNININIGNGIPTNIEKMTFEDSETQKLNIKQQSNNNTSTSVCVSSIHSSSPISSPTSHQVNKSSGSLPPVIKRSPTTTHHHNSSGSNSSSSSSGSNNNNNQIKTSNGMNKPNPTGFLFGSKPRENSQNKIDDNKGVNLAVSTSNSSNNFHKSHSESNIININAPPVETVNMEEIYNNIPSSISMENIRENENNNNSSNNNSNNNNNNNNNNNNSNNINNVNGNKSSLASSTSSISSLSSVSTLSTSNAATNTNTNANTTSTTKTTSTVRSTSPTQFKPRVEFDENNPNAIILSRQRCKSISSPSDFRLNPPSNVHMPTSSLSTSTSTTNVNGLLLPNGVGGVSMSFTPSGLPMTPPTNSSQVDTLQMSTESITIQPSSLDSSSESVSDGLQSVSGSPVTASPSPTISNNTNATTTNNNNNTNTNNNNNNNNNQHNHHHHQHSHSQQHDVYQIKKENFPSSPTSPTLLPSETHDFSSEYSSNPGGKCAICRKPLWSFPISDKSRRCRDCSLVVHRACVPLATECPSAKKSPSKLSVPNGNQSNSSSSSSSSSSSSSSSNSSSSNTKGHSRTPSSPSVSSIPGFQLTSNASQNLHVNSHTLSLLVNGATIDSNHYKRNKKSLEAGARDFHFIFRGCGIPLDEFPLDSYVCGLYSYFAHGRLYLTESYVCFYDGFVFDRTKERTKIIKVSNIASIEKRSSGLNPSAIKIKTFDDQSFIFTHFMHREVAFDDLEGLLIHQESLHFAHSIVANNFPGMNEAIRGQTKRLLSRARLDGHYQIHSKIRCPMPSKEILLMSAIKNNNLDMVVTLLNYYCQVNSDEINSVDSKGYTPLHNAVFSECSDQIFMHLLNQKEVRVRERNMDGNTPLHYFCQKFKSPECQRIVQAMIEKGANINEQNYNGETPLHKAIFNHSVRLLMVYILLKNNANVNIVNNAGESPLHYAVRLGRLDVAKMLLAAGADPTIISLRDRKTALALAVDYDVCPEISDLLRRLDTITTSLEMYELEKFQASLVVEELQKENVVARLDEKLLDKIGCTDKEERRKFLSLKSNRLLIHHPARTQGAKIILKEMETMDIKNGKLIISETELEYTEKIGSGASGKVFKGIYRGRVVAIKVLKSADDEMTREDFLKEFGVLASLESHTIVGLYGVVLEPKICLVMEYCSNGSIYHSIRKNPPSWERFFSFVQQMLAGINALHQSTPQVLHRDIKTLNFLVNHNNKVKVADFGLSRFNTESNQETLNKTRGTSVYCAPEVFEGKEYNERSDMYSMGIVMWEIVYCVVYGCYMIPYQEYNKMFNAFQVALLVNSSKRVLRPTIPIGVPQVLKDLIYCLWDHDVSSRPTATEAMTALAVCEKEYKQNKAQWELVITKKEPTPLPRVAPLPAFPGYRQFYEQNLDIKPIPEEEQIYQEAMEKQRRNQEASANRNQKNKELLNNNN
What is the function of this protein?
Involved in the development of the fruiting body.  Overexpression phenocopies the spnA null phenotype.
What are the official names of this protein?
Ankyrin repeat-containing protein kinase A, Ankyrin repeat-containing protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Membrane. Nucleus. Note=Localized in the subcortical region of the cell with some enrichment in cell protrusions. In developed cells, colocalized with spnA. May translocate to the nucleus in response to a regulatory signal.
Protein: GREA_RUTMC
Sequence: MENIPMTVFGAKVLEAELLKLKNVSRPRIIENIVTARAHGDLKENAEYHAAKEEQGFIEGRIKEVESKLSRMQVIDVTKLNQDGRCVFGTTITLMNIEDDSETTYKIVGEDEADIILGKISCHSPIASALMGNEEGDEVTVKAPKGDIVYEVLSVEYI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: Y5813_SACEN
Sequence: MTGRQREREQRPQPQTGDQGHPRRWLILVALCAALLVIVIDNTVLNVAIPEIGRTFDASTGELQAVLDSYVVVCGGLLVAAGALSDRCGRRRVMVAGLVVFGLTSAGAALAPSVWWLIGMRAAMGVGAALVMPATLAIMVRVFPPHERPKAFAAWTAVGSVALGLGPLLGGALVDLWSWAGIFLVNLPFVAVALAGVVRLVPESRDPAAGAPDLPSTVLVTTGMVALVWAVIAVPERGALATPVLAATALAVVSLAWFGVRQRRASAPMVDFGLYRDRRFAGASSAIALIAVATGSTLFVLSQYLQLVRGHSAVVAGMAALPLAAGSVVGSALGARAPARIGYRACIVTGFAVTAAGFGVLAALGPDSGQPHIAFGLLLCGFGTGFAGPAATSTALGAVPADRAGMGSALNDTHQQLGIAFGVAVLGGLLSTAYRAFLPTGVPHDASTSLAATLSFADERTSAALADAARLAFTQAQSATMTAGLACALAGAAVAMLSLRSGRRAPSR
What are the official names of this protein?
Uncharacterized MFS-type transporter SACE_5813.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IKBA_HUMAN
Sequence: MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL
What is the function of this protein?
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals.  On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
What are the official names of this protein?
NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3.
What is the protein family that this protein belongs to?
Belongs to the NF-kappa-B inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Protein: PLIN1_MOUSE
Sequence: MSMNKGPTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYNSTKEAHPLVASVCNAYEKGVQGASNLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKGTISTRLRSARNSISVPIASTSDKVLGATLAGCELALGMAKETAEYAANTRVGRLASGGADLALGSIEKVVEFLLPPDKESAPSSGRQRTQKAPKAKPSLVRRVSTLANTLSRHTMQTTAWALKQGHSLAMWIPGVAPLSSLAQWGASAAMQVVSRRQSEVRVPWLHNLAASQDESHDDQTDTEGEETDDEEEEEESEAEENVLREVTALPNPRGLLGGVVHTVQNTLRNTISAVTWAPAAVLGTVGRILHLTPAQAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPSAEAERKGSGARPASPESTPRPGQPRGSLRSVRGLSAPSCPGLDDKTEASARPGFLAMPREKPARRVSDSFFRPSVMEPILGRAQYSQLRKKS
What is the function of this protein?
Modulator of adipocyte lipid metabolism.  Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL).  Its absence may result in leanness (By similarity).  Plays a role in unilocular lipid droplet formation by activating CIDEC.  Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer.  May modulate lipolysis and triglyceride levels.
What are the official names of this protein?
Perilipin-1, Lipid droplet-associated protein, Perilipin A.
What is the protein family that this protein belongs to?
Belongs to the perilipin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Lipid droplet. Note=Lipid droplet surface-associated.
Protein: PNU1_SCHPO
Sequence: MSSNLIKSFGLIAIGAISGVTFTHFYYKGYQGSDVPDLTPRYTKFDSAGRALESIYDFNATKFFQYGIPGPVADQRVNHGYMSVFDRRTRNPFYTAETITQESLNQRKGNRRYSEFVPDDNIPEMFQAKLGDYRGSGYDRGHQVPAADCKFSQEAMNETFYLSNMCPQVGDGFNRNYWAYFEDWCRRLTSKYGSVTIMTGPLYLPKKNERGQWEVQYRVIGNPPNVAVPTHFFKVIIAEKSGEPTSSPSVAAFVLPNKPIADNFPLKNFAVPVEVVERASGLEILSNVPKGNRKQLCSEVVCQLNVKEFVESVKQKQKNQGK
What is the function of this protein?
This enzyme has both RNase and DNase activity.  It degrades single-stranded DNA and RNA.
What are the official names of this protein?
Nuclease 1, mitochondrial, SpNUC1.
What is the protein family that this protein belongs to?
Belongs to the DNA/RNA non-specific endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: RS2_LACLM
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMKPYIFTERNGIHVIDLQKTVKLVDDAYNYVKNASQEGAVVLFVGTKKQAAEAVKEEALRAGQYYVNHRWLGGMLTNWNTIQTRVTRLKEINKMEEEGTFEVLPKKEVVLLNKERERLEKFIGGIADMPRIPDVMYIVDPHAEQIAVKEAKTLGIPVVAMVDTNADPEPIDVVIPANDDAIRAVKLITAKMADAIIEGRQGEDAAEDFVAEEAASEESLEELAEIVEGK
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RSMH_STRT1
Sequence: MTNEFHHVTVLLHETVDMLDIKPDGIYVDATLGGAGHSSYLLSQLSEKGHLYCFDQDQKAIDNAQVRLKDYIDKGMVTFIKDNFRNLKSNLEALGVSEIDGILYDLGVSSPQLDERERGFSYKQDAKLDMRMNEEASLTAYDVVNTYPYNDLVRIFFKYGEDKFSKQIARKIEQARQVKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQEALDLLAVDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPFIPEDLQPKVALVNRKPILPSQEELEANNRSHSAKLRVAKKIRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAP1_ORYSJ
Sequence: MLGHLVGLVKVRVVRGVNLAVRDLRSSDPYVIVRMGKQKLKTRVIKKTTNPEWNDELTLSIEDPAVPVRLEVYDKDTFIDDAMGNAELDIRPLVEVVKMKIEGVADNTVVKKVVPNRQNCLAEESTIYISEGKVKQDVVLRLRDVECGEIELQLQWVDIPGSKGV
What is the function of this protein?
Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity (By similarity).  Stimulates the GTPase/ATPase activities of YCHF1, and regulates its subcellular localization (PubMed:19086295, PubMed:20876569, PubMed:23550829).  Binds phospholipids in a Ca(2+)-independent manner (PubMed:20876569).  Promotes tolerance towards salinity stress by limiting the accumulation of reactive oxygen species (ROS) (PubMed:19086295, PubMed:23550829).  Promotes resistance to bacterial pathogens, such as Xanthomonas oryzae pv.  oryzae and Pseudomonas syringae pv.  tomato strain DC3000 (PubMed:19086295).  Binding to YCHF1 is required for its role in stimulating defense responses and the ability to alleviate salt stress (PubMed:26286751).
What are the official names of this protein?
GTPase activating protein 1, OsGAP1, G-protein binding protein 1, OsGPBP1.
What is the protein family that this protein belongs to?
Belongs to the plant CAR protein family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Cytoplasm, cytosol. Note=Localized mainly in the cytosol under NaCl treatment, but translocates to the plasma membrane upon wounding.
Protein: RNC_YERE8
Sequence: MNPIVINRLQRKLGYTFQQQELLLQALTHRSASSKHNERLEFLGDSILSFVIANELYRRFPRVDEGDMSRMRATLVRGNTLAEMAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGIFLDSDIHTIERLILAWYHSRLEEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLNEPVIGTGSSRRKAEQAAAEQALKQLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARY1_RAT
Sequence: MDIEAYFERIGYKNSVNKLDLATLTEVLQHQMRAVPFENLSMHCGEAMCLGLEATFDHIVRKKRGGWCLQVNHLLYWALTKMGFETTMLGGYVYITPVNKYSSEMVHLLVQVTISDRNYIVDSAYGSSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQDVPNQEFVNSDLLEKSKYRKIYSFTLEPRTIEDFEYVNTYLQTSPASVFVSTSFCSLQTSEGVCCLIGSTLTSRRFSYKDNVDLVEFKSLTEEEIEDVLKTTFGISLEKKFVPKHGELVFTI
What is the function of this protein?
Participates in the detoxification of a plethora of hydrazine and arylamine drugs.  Acetylates both arylamines and arylalkylamines.
What are the official names of this protein?
Arylamine N-acetyltransferase 1, Arylamide acetylase 1, N-acetyltransferase type 1, AT-1, NAT-1.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAG_META3
Sequence: MMIEIGTTKYVIYAKVIVDGYVEKHDIIGAIFGQTEGLLGSDLDLRDLQKSGRIGRIDVELENINGKSYAKLIFPSSLDRVETAIIAATIETLDRVGPCIATIKVLNIEDIRIKKRQYITDRAKELLKSIVDTTIDTYEIAEEIKEFVRSEEIIEMGNEKLPSGPNVEDSDTIIIVEGRADVLNLLRCGIKNAIAVGGTSIPESIIELSKKKTTTIFTDGDRGGELILKEAIQTCDIDYVARAPKGREVEELTKKEVVKYLRSKIPIEQYIQFHSNKCNELLKKSKEYRSNTINNNNDSGKISIDSIISENATNDIGELPVSKTSKNERNNTKVIDENIEKNNQNIKEDNNIEIKQSDISEILKKDCSEQWEYIESLLNDISNTDNIKIITNDNIIKTIHYSELDKIDKSDIQMVMSDMPITQKITDLFHECSPIIIGRDINITKKPAKLKVFSHDMLKNMVCL
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.