PharMolix/UniProtQA huggingface dataset:
Protein: PHR_NEUCR
Sequence: MAPSKRKASAPPQTSHVNGNPSADKKRKTTTDAPPTNPNTSSDPLRAPHPFYKDSETHGIVLRKFYPHEMSNARAQAYNDNELPRPIETLSAALAETAALRKSLPVRQAVVHWFKMDLRLHDNRSLWLASQKAKEAGVPLICLYVLSPEDLEAHLRAPIRVDFMLRTLEVLKTDLEDLGIPLWVETVEKRKEVPTKIKELMKSWGASHLFCAMEYEVDELRREAKLVKLLAEGEKGEKMAADVVHDTCVVMPGALQSGSGGQYAVYSPWFRAWIKHIEENPECLEIYEKPGPNPPGTKEKHENLFACSIPEAPEGKRLRDDEKARYHSLWPAGEHEALKRLEKFCDEAIGKYAERRNIPAMQGTSNLSVHFASGTLSARTAIRTARDRNNTKKLNGGNEGIQRWISEVAWRDFYKHVLVHWPYVCMNKPFKPTYSNIEWSYNVDHFHAWTQGRTGFPIIDAAMRQVLSTGYMHNRLRMIVASFLAKDLLVDWRMGERYFMEHLIDGDFASNNGGWGFAASVGVDPQPYFRVFNPLLQSEKFDPDGDYIRKWVEELRDLPELKGGKGGEIHDPYGRGSEKVKKKLEEKGYPRPIVEHSGARDRALDAYKRGLARDL
What is the function of this protein?
Involved in repair of UV radiation-induced DNA damage.  Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
What are the official names of this protein?
Deoxyribodipyrimidine photo-lyase, DNA photolyase, Photoreactivating enzyme.
What is the protein family that this protein belongs to?
Belongs to the DNA photolyase class-1 family.
Protein: PCY1_CAEEL
Sequence: MFIHKQEKMPQRKRTMDSPQEEDVEVKKKATEVEYVVRSLASDEPAPFSDEALAITTREAVDYSKKITLAMAEANEAGRPVRIYADGIYDLFHHGHANQLRQVKKMFPNVYLIVGVCGDRDTHKYKGRTVTSEEERYDGVRHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVAPGEEDLYEKFRREGMFLETERTEGVSTSDVVCRIIRDYDKYVRRNLQRGYSPKELNVGFLAASKYQIQNKVDSLKSKGIELLSTWKSKSDDIIRDFIDTFHKDGGLNAFGGRLKGIMSMSRSPSPSPHEGSPTGIEHHLETQDEEEEEEALEEEKVVEQKIVEKKEVVKKRSSRNKAKTPLEY
What are the official names of this protein?
Putative choline-phosphate cytidylyltransferase, CTP:phosphocholine cytidylyltransferase, CCT, CT, Phosphorylcholine transferase.
What is the protein family that this protein belongs to?
Belongs to the cytidylyltransferase family.
Protein: RL16_HELPS
Sequence: MLMPKRTKYRKQMKGRNRGKAHRGNSIAFGDIAIKAIEHGRIDSRQIESARVAMTRHIKRAGKVWIRVFPDKPLTAKPLETRMGKGKGSVEKWVMNIKPGRIVYEMLGIEEGLAREALALAQSKLPFKTKIVTCESENEIY
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: C71BM_ARATH
Sequence: MSISLYFLLLLPLFLIFFKKLSPSKGKLPPGPLGLPIIGNLHQLGKSLHRSFHKLSQNYGPVMFLHFGVVPVVVVSTREAAEEVLKTHDLETCTRPKLTATKLFSYNYKDIGFAQYGDDWREMRKLAMLELFSSKKLKAFRYIREEESEVLVNKLSKSAETRTMVDLRKALFSYTASIVCRLAFGQNFHECDFVDMDKVEDLVLESETNLGSFAFTDFFPAGLGWVIDRISGQHSELHKAFARLSNFFQHVIDDHLKPGQSQDHSDIIGVMLDMINKESKVGSFQVTYDHLKGVMSDVFLAGVNAGAITMIWAMTELARHPRVMKKLQQEIREILGDNKEKITEQDLEKVHYLKLVIEETFRLHPPAPLLLPRETMSDLKIQGYNIPKNTMIEINTYSIGRDPNCWENPNDFNPERFIDSPVEYKGQHYELLPFGAGRRICPGMATGITIVELGLLNVLYFFDWSLPDGMKIEDIDMEEAGAFVVAKKVPLELIPTPHQW
What are the official names of this protein?
Cytochrome P450 71B22.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GATB_PSEPK
Sequence: MQWEVVIGLEIHTQLATQSKIFSGSATTFGSEPNTQASLVDLGMPGVLPVLNEQAVRMACMFGLAIDAEIGKRNVFARKNYFYPDLPKGYQISQMDLPIVGKGHLDIALEDGTIKRIGVTRAHLEEDAGKSLHEDFSGSTGIDLNRAGTPLLEIVSEPDMRSAKEAVAYVKAIHALVRYLGICDGNMAEGSLRCDCNVSIRPKGQTEFGTRCEIKNVNSFRFIERAINSEIQRQIDLIEDGGKVVQETRLYDPNKDETRSMRSKEEANDYRYFPDPDLLPVVIEDSFLETIRAGLPELPPQKVERFQTQYGLSAYDANVLASSREQADYFEEVVKIGGDAKLAANWVMVELGSLLNKLGVEIDQAPVSAAQLGGMLLRIRDNTISGKIAKTVFEAMAAGEGDADSIIESKGLKQVTDTGAIDKMLDEMLAANAEQVEQYRAADEAKRGKMFGFFVGQAMKASKGKANPGQVNQLLKAKLEG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: MTLD_CROS8
Sequence: MKALHFGAGNIGRGFIGKLLADAGVGLTFADVNQTVLDALNARHSYQVRVVGEQEQIDTVSGVDAVNSTSEDVVTLIATVDLVTTAVGPVVLERIAPAIAKGLVLRKAQGNERPLNIIACENMVRGTSQLKTHVFNALEEGDKAWVESHIGFVDSAVDRIVPPSASAAHDPLEVTVETFSEWIVDKTQFKGELPTIAGMELTDNLMAFVERKLFTLNTGHAITAYLGKQAGHQTIRDAILDEKIRLVVRGAMEESGAVLIKRYGFDDAKHAAYIEKILSRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHQNLVLGIAAAMHFRSEDDPQAQELAQLIADKGPQAALAQISGLDANSDVVASAVNAYNATA
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: CAIT_SHIDS
Sequence: MKNEKRKTGMEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGGRIASDVPSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWSVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRGGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine.
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOK_PSEP1
Sequence: MGAIPLEHGLAVAGILFCLGLVGLMVRRNILFVLMSLEVMMNASALAFVVAGARWVQPDGQVMFILVISLAAAEASIGLAILLQLYRRFHTLDIDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRAB_IDILO
Sequence: MSRDLNDLLTQSEETVQALIADGAETELLYEIEHHLASQDFTKLEKAAVELVKQGYHVDDADEFEDERGKRWFAFMAVTDAELDNDILNRQVREIAAIADECEVEYDGWGTLIEDEELDDEDLDDGEE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity B.
What is the protein family that this protein belongs to?
Belongs to the RraB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STEA1_PIG
Sequence: MESRQDITNQEELWKMKPRKNLEDDYLNEDSRENSMPKRPMLVHLHQTAHFDEFDCPPELQHKQELFPKWHLPIKIAAIVSSLTFLYTLLREVIHPFVTSHQQYFYKIPILVINKVLPMVSITLLALVYLPGVIAAIVQLHNGTKYKKFPHWLDRWMVTRKQFGLLSFFFAVLHAVYSLSYPMRRSYRYKLLNWAYQQVQQNKEDAWIEHDVWRMEIYVSLGIVTLAILALLAVTSIPSVSDSLTWREFHYIQSTLGIVSLLLGTIHALIFAWNKWVDIKQFIWYTPPTFMIAVFLPTVVLICKVILLLPCLRRKILKIRHGWEDVTKINKTEMSSQL
What is the function of this protein?
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+).  Uses NAD(+) as acceptor.
What are the official names of this protein?
Metalloreductase STEAP1, Six transmembrane endothelial antigen of PAEC, Six-transmembrane epithelial antigen of prostate 1.
What is the protein family that this protein belongs to?
Belongs to the STEAP family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: GLNA_MOUSE
Sequence: MATSASSHLNKGIKQMYMSLPQGEKVQAMYIWVDGTGEGLRCKTRTLDCEPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRKDPNKLVLCEVFKYNRKPAETNLRHICKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWIARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRGASIRIPRTVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCLLNETGDEPFQYKN
What is the function of this protein?
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity).  Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (PubMed:25870278).  Essential for proliferation of fetal skin fibroblasts (By similarity).  Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development (PubMed:30158707).  Involved in angiogenesis by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation (By similarity).  May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (By similarity).  Plays a role in ribosomal 40S subunit biogenesis (By similarity).
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Palmitoyltransferase GLUL.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Microsome. Mitochondrion. Cell membrane; Lipid-anchor. Note=Mainly localizes in the cytosol, with a fraction associated with the cell membrane.
Protein: Y288_METJA
Sequence: MKKFSAIFGLLSVIFVIMAISQVSGLSGAITPPKIDIMVNASNGLPQDINSIIYVKNPNSFPVKVEMVTTGDLNNSKKVEVKIMKNNFTLKPGETVGVNITFTVKEKDNYEGDILTKISPVDYGDDKKGVNLKASVVLPTKVAIMVVGNEIHTKELVITAVLIISILGLGAMLIRRHL
What are the official names of this protein?
Uncharacterized protein MJ0288.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: M5_STRP5
Sequence: MARENTNKHYWLRKLKKGTASVAVALSVLGAGLVVNTNEVSAAVTRGTINDPQRAKEALDKYELENHDLKTKNEGLKTENEGLKTENEGLKTENEGLKTEKKEHEAENDKLKQQRDTLSTQKETLEREVQNTQYNNETLKIKNGDLTKELNKTRQELANKQQESKENEKALNELLEKTVKDKIAKEQENKETIGTLKKILDETVKDKIAKEQENKETIGTLKKILDETVKDKLAKEQKSKQNIGALKQELAKKDEANKISDASRKGLRRDLDASREAKKQLEAEHQKLEEQNKISEASRKGLRRDLDASREAKKQLEAEQQKLEEQNKISEASRKGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDTKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN
What is the function of this protein?
This protein is one of the different antigenic serotypes of protein M.  Protein M is closely associated with virulence of the bacterium and can render the organism resistant to phagocytosis.
What are the official names of this protein?
M protein, serotype 5.
What is the protein family that this protein belongs to?
Belongs to the M protein family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: KCMA1_XENLA
Sequence: MATWNASQIILNSMSNIIESPQSKPRPVMASNGASLFIPVTMEVPCDQGTRMWWAFLASSMVTFFGGLFIILVWRTFKYLWTVCCHCGGKNKEAQKVVNVASSQVTDGDYKPTDDKEEVGVAEVGWMTSVKDWAGVMISAQTLTGRVLVVTVFALSIGALMIYFIDSSNPIESCQNFYKDFTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFENSQDLSYWECMYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKKHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKDGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEYKSEKGESRILINPGNHMKIKEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCACKRLEDEQPSALSPKKKQRNGGMRHSPNTSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELKHIVFVGSLDYIKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPLHGVARQASITTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALVAEENALRGGYSTPQTLANRDRCRVAQLALYDGPFADLGDGGCYGDLYCKALKTYNMLCFGIYRLRDAHISTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNASQSRASLSHSSHSSHSSSKKSSSVTSILHTASANRQNRVKARDSRDKQKMGQAEKKWYTDETENNYPRNIQIKPMSTHMANQINQYKSTSSLIPPIREVEDEC
What is the function of this protein?
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+).  It is also activated by the concentration of cytosolic Mg(2+).  Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane.  It therefore contributes to repolarization of the membrane potential.  Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity.  In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential.  In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map.  Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX) (By similarity).
What are the official names of this protein?
Calcium-activated potassium channel subunit alpha-1, BK channel, BKCA alpha, Calcium-activated potassium channel, subfamily M subunit alpha-1, K(VCA)alpha, KCa1.1, Maxi K channel, MaxiK, Slo-alpha, Slo1, Slowpoke homolog, Slo homolog, xSlo.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PRMA_PSYWF
Sequence: MDWQQLHLQCAKQDVDLAESLLLEEGALSISLEDAGDQPLFEPLPGQSPLWDEVILTGLFTADTAQDIESMAQTLAAQVNARRVWTTALADTDWEREWMSHYVPIECTNNLWIVPKWMTPPNPDAVNIMMDPGLAFGTGYHATTRLCLDWLTDQDLSDKVIIDYGCGSGILGIAALLLGAKQVYSVDIDPQAVLATKQNAERNDVTHALEVYLPEDFAKAFAAGDIPKADIITANILAKPLMELAPYLATLIKPKGGIVLAGLISEQLEDMVRAYEPWFNLDTRHSYEKSDDHDDSHWHRLSGTFTG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_PROM2
Sequence: MVALRLIPCLDVANGRVVKGVNFVNLRDSGDPVELACRYSDEGADELVFLDIRASVENRNTLVNLVSRTAKSVKIPFTVGGGIDSVSSINDLLRAGADKVSLNSSAVINPDLISESSREFGNQCIVIAIDARRKVDKVGEWEVYVKGGRENTGIDVLSWAKKVEELGAGEILLTSMDGDGTQNGYDLHLTESVANIVDIPVIASGGAGSLEDIYDVFKEGRASAALLASLLHDKKLTLKEIKTFLLEKKLPIRPYE
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPB8_HUMAN
Sequence: MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQDSQEVTCT
What is the function of this protein?
Displays temperature-dependent chaperone activity.
What are the official names of this protein?
Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock.
Protein: RL6_CLOAB
Sequence: MSRVGKQPVEIPSGVTVTVTPDNVVTVKGTKGQLEKAMHKDMKIAVEDNKVVVTRPSDSKNHKALHGLTRALINNMVIGVTEGFSKTLQLVGVGYKAQLKGKSLILNLGYSHPIEVASIEGVTFEIPDANTVVVKGINKELVGSVAADIRTFRKPEPYKGKGIKYSDEVIRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PURA_MYCMM
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPSGENFALHLIPSGVLTPGVTNVIGNGVVIDPGVLLSELKGLEDRGVDTSKLLISADAHLLMPYHVAIDKVTERYMGSKKIGTTGRGIGPCYQDKVARMGIRVADVLDTDQLAHKVEAALEFKNQVLVKIYNRKALDPDQVVESLLEQAEGFRHRIADARLLLNNALEAGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAVGSGIGPTRIRTVLGILKAYTTRVGSGPFPTELFDESGEYLSKTGGEFGVTTGRRRRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPVCVGYEIDGKRTSEMPMTQSDLCRAKPVYEELPGWWEDISAAREFDDLPAKARDYVLRLEEIAGAPVSCIGVGPGRDQTIVRRDILQERA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTEN1_ARATH
Sequence: MGLKLSRGPVKEKSPLEFTRVHILTYFTTNSYLRNLVSKKRRRLIIGGYDLDMSYISDKLLAMSFPAERMRAVYRNPLWQVKSVLDMRHPDHYKVYNLCIEESYDPDNFYGRVERFPFDDNHVPSLKMIQLFCESVHSWLSLDPKNIAVVHCMAGKGRTGLMVSAYLVYGGMSAEEALEMYASRRTTNNNGVSIPSQRRYVKYWSDLLSFSKKGPPEVKLPQEHSRELLRIRLYDTANVDSVFFVVSELQEVPNEMYRPSVELARGCCRQFKKGYCRSSSPRYYISHVNCDSEEDEEVTDGEEPHLVVQMDTESSIIDEKTCLDFYFDKPVRVSGDIRITFYQKMIGSRLFYTCFNTAFITNGLLQFSIGELDKVGGNGRSISGPDFSLELLFGPACSKFGKFLSRDDLSLS
What is the function of this protein?
Protein tyrosine phosphatase that exhibits also lipid phosphatase activity.  Can use phosphatidylinositol substrates such as PtdIns(3,4,5)P(3) as substrate.  Pollen-specific phosphatase required for pollen development.
What are the official names of this protein?
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1, Protein PHOSPHATASE AND TENSIN HOMOLOG 1, AtPTEN1.
What is the protein family that this protein belongs to?
Belongs to the PTEN phosphatase protein family.
Protein: RPOB_MARN8
Sequence: MTYSYTEKKRIRKDFSKLPSVMEVPYLLSIQLDSFRDYLQMETAPEDRRETGLHAAFKSVFPIVSYSGNAALEYVSYRIGEPVFDVKECQLRGVTYAAPLRVKVRLIIYDKESSNKAIKDIKEQEVYMGEMPLMTENGTFVVNGTERVIVSQLHRSPGVFFDHDKGKTHSSGKLLYSARVIPYRGSWLDFEFDPKDAVFVRIDRRRKLPASILLRGLGYTSEQMLEMFFETSKFSLGAEVCKLELVPSRLRGDIATFDIKDNDGNVIVEEGRRITARHIKQLEKAGITELEVPTEYLYGRVLAKDMIDQSTGEVLVECNTELTEEVVTKILDAGVKDIETLYTNDLDCGPFMSDTLRIDPTRTPLEALVEIYRMMRPGEPPTKESAENLFNNLFFSEERYDLSAVGRMKLNRRLGREESTGEGTLTHDDIIDVLKTLIAIRNGQGQVDDIDNLGNRRVRCVGEMAENQFRVGLVRVERAVRERLSLAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLATYARSNSYGFLESPYRKVVDGVVTDEVVYLSAIEESNYVIAQASAATDEGKRLTDELVTVRHQNEFTVAPPEAVNFMDVSPRQVVSVAASLIPFLEHDDANRALMGANMQRQAVPTLKSQVPLVGTGVERTVAQDSGVCVTARRGGVIESVDAARIVVRVNNEETEAGDAGVDIYNLTKYTRSNQNTCINQRSIVRQGDVIARGDVLADGPSVDLGELALGQNMRIAFMPWNGYNFEDSILISEKVVQEDRLTTIHIQELTCVARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVGPGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSQRVPTGTRGTVIDVQVFTRDGIEKDARALSIEKEQLDKYRKDLKDEYRIVEGATFERLMAALKGQEVISGPGLKKGAKLEEAYLAELPRADWFKLRMKDEALNELLEKSEQGLEDRKKEHEARFDDKKGKLQQGDDLAPGVLKIVKVYLAIKRRIQPGDKMAGRHGNKGVISAVMPIEDMPYDEFGNTVDIVLNPLGVPSRMNVGQVLETHLGAAAKGLGERISRMLDEQRKVAELRKLLDEIYNHSDEVFKVDLDSLTDKEIFELCNNLRGGVPMATPVFDGAKEAEVKRMLELAGLDTTGQTKLYDGRTGDAFDRPVTVGYMYILKLNHLIDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLVKEIRSLGIDIELESE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: F1142_BOVIN
Sequence: MSNKDDLETAVITEATPIREDENCEPVKNFESVDQSAKSESKSEPVASTRKRPESKPSSDLETEVLPVQASQAAGKETVSKDVPQSGWGYWGSWGKSLLSSASATVATVGQGISNVIEKAETSLGIPSPSEISTEVQYATGETSAKENGNSSPMSGPFGVFSTISTAVQSTGKSVISGGLDALEFIGKKTMDVIAEGDPGFKRTKGLMNRTSTLSQVLREAKEKEELWTSNEVTMETDKKTHYGLLFDEFQGLSHLEALEMLSRESEIKVKSILNSLSGEELETLKLELEQLKEAFSLAELCEEEEEEKKGGEDFTKEITELFSQLHVSSKPEKLARARNTAYEWIRTSLAKPLKEKEEGEKQLEAENTEQINNKSIEDIHAFAIRSLAELTACSIELFHKTAALVLHGRKQEVTTIERSRALCQMTVLLCKELSCLSKEFTTCLTTAGVKEKADVLNPLITAVFLEASNSASYIQDAFQLLLPVLEISFIENKTELPEA
What are the official names of this protein?
Protein FAM114A2.
What is the protein family that this protein belongs to?
Belongs to the FAM114 family.
Protein: P85A_BOVIN
Sequence: MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEAKPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGPSKTEADSEQQASTLPDLAEQFAPPDVAPPLLIKLVEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDTASLDLEMFDVHVLADAFKRYLLDLPNPVIPVAVSSELISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSELFSPLLFRFPAASSENTEHLIKIIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNETEIQRIMHNYEKLKSRISEIVDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
What is the function of this protein?
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.  Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.  Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB.  Likewise, plays a role in ITGB2 signaling.  Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).
What are the official names of this protein?
Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha.
What is the protein family that this protein belongs to?
Belongs to the PI3K p85 subunit family.