PharMolix/UniProtQA huggingface dataset:
Protein: KBAZ_SALAR
Sequence: MKHLTNMVEQHKRGKANGIYAVCSAHPLVLESAIRYAHANHTPLLIEATSNQVDQFGGYTGMTPADFRDFVCQLADSLGFPQSELILGGDHLGPNRWQNLPATQAMANADDLIKSYVAAGFKKIHLDCSMSCADDPVPLTDEIVAERAARLAKVAEETCQQHFGKSDLVYVIGTEVPVPGGAHETLTELEVTTPEAARATLEAHRYAFEKQGLDAIWPRINALVVQPGVEFDHTQIIDYQPQKATELSKMVETYDMLVFEAHSTDYQTPQSLRQLVKDHFAILKVGPALTFALREALFSLAAIEEELLPAKACSGLRHVLESVMLDRPEYWQNHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFERLVRNLADEPIPLPLISQYLPLQYVKVREGDLNATPRELIISHIQDILQQYHAACYGTTFYNE
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of KbaY.  When expressed alone, KbaZ does not show any aldolase activity.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. KbaZ subfamily.
Protein: MGLA_YERPE
Sequence: MADINTAQPRDWLLEMSNIDKSFPGVKALDNVNLKVRPYSIHALMGENGAGKSTLLKCLFGIYKKDSGSIIFQGQEIEFKSSKEALEQGVSMVHQELNLVLQRTVMDNMWLGRYPTKGFFVDQDKMYKETKAIFDELDIDIDPRDKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKARGCGIVYISHKMEEIFQLCDEITILRDGQWITTQPLDGLTMDQIISMMVGRSLSQRFPDRLNKPGEVILEVKNLTSLRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKVTGTIKLHGKNINNHSANEAINHGFALVTEERRSTGIYAYLDISFNSLISNIRNYKNKFGLLDNTRMKSDTQWVIDAMRVKTPGHRTNIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLMTELAKKDKGIIIISSEMPELLGITDRILVMSNGQVAGIVDTKQTTQNEILRLASLHL
What is the function of this protein?
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Galactose/methyl galactoside import ATP-binding protein MglA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VE8E2_HPV57
Sequence: MAIRRWLLERQKSTQAATSDDDTLSPLRSAAAAVTATATATTAVPPTLQDSAQAPSSPPPKRQRVIVGQQWQQPDSTRKVREGQVECQNDRSIRNPDSTDPRRGHSDLDAVPVIHLQGEANCLKCFRYRVQKHKDVLFVKASSTWHWACGNGDKTAFVTLWYKSQEQRAEFLTRVHLPKGVKALPGYMSAFV
What is the function of this protein?
Plays a role in limiting the replication of viral DNA in keratinocytes.  Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.
What are the official names of this protein?
Protein E8^E2C.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E8^E2C protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: GCST_BACCN
Sequence: MITLQRTPLFDVYAKYGGKTIDFGGWELPVQFSSIKEEHEAVRTAAGLFDVSHMGEVEVTGADSLAFLQRVVTNDVSTLKVGGAQYTAMCYENGGTVDDLLIYKRGEEDYLLVINASNIEKDYEWLASHVIGDTKVVNVSNEIAQLAIQGPKAEGILQKVVSEDLKEIKFFKFKNDVLVDGIPALVSRTGYTGEDGFEIYCKSEDAIKIWEKLLEVGEEDSLKPCGLGARDTLRFEATLPLYGQELSKDITPIEAGIGFAVKTNKEADFFGKEVLKEYKENGAPRKLVGIEVIERGIPRTHYPVYVGEEKIGEVTSGTQSPTLKKSIGLALIDVKYAAIDTEVEIEIRKKRVKAVVVPTPFYKRSK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: Y246_MYCGE
Sequence: MDNIKVLFLGDVYGKAGRKIISDHLPIIKKKYQLNLIIANAENTTNGKGLSWNHYQILKQAGIDYITMGNHTWFQKQDLELVLNQVDVIRPLNLMQDFNYFQLGKGSYLFSLNGLKIRITNLLGTSINLPFAITNPFVELKKLVLTKDCDLHIVDFHAETTSEKNAFCMVFDGYVTAILGTHTHVPSNDLRITPKGSVYITDVGMCGPGFGSVIGANPKQSIKLFCTGERQFFEVSNCGAQLNGVFFEVCSKTNQVVKIEQIRIVLDDEKYLANDYFNLVE
What are the official names of this protein?
Putative phosphatase/phosphodiesterase MG246.
What is the protein family that this protein belongs to?
Belongs to the YmdB-like family.
Protein: MNME_STAAT
Sequence: MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVIEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSA_ECOUT
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LBP_RENRE
Sequence: PEVTASERAYHLRKMKTRMKRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLAPGVRISVEEAAVNATDSLLKMKAEEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQAVGPDITDDKAITCFNTLDFNKNGQISRDEFLVTVNDFLFGLEETALANAFYGDLL
What is the function of this protein?
This Ca(2+)-dependent protein binds to luciferin.  The luciferin of LBP is capable of reacting with luciferase and O(2) only when calcium is bound.
What are the official names of this protein?
Luciferin-binding protein, LBP.
Protein: QUEC_ECOLU
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: KTHY_BRUA1
Sequence: MSGLFITFEGGEGAGKSTQIALLASHLRNHGFDPVITREPGGSPGAEAIRHVILSGNAETYGPAMEALLFAAARADHVDQLIRPTLAEGRIVLCDRFIDSSRAYQGVTGNLDATYMAAIERIAIDGAMPDLTLVLDICAERGLSRAGKRRGSDTADRFEKEDIAVHEARRQAFLEIARQEPARCKVIDADRSQEKIADEIRSVVDTILTEKGLL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TX405_LYCSI
Sequence: MKVLVLFSVLFLTLFSYSSTEAMDEFDSDAEEDMLSLMANEQVRAKACTPRLHDCSHDRHSCCRGELFKDVCYCFYPEGEDKTEVCSCQQPKSHKYIEKVVDKARTVVG
What is the function of this protein?
Enhances the high-affinity desensitization of human P2RX3 purinoceptors.
What are the official names of this protein?
U4-lycotoxin-Ls1d, U4-LCTX-Ls1d, Toxin-like structure LSTX-C5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 05 (U4-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PA1B2_RAT
Sequence: MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDIDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
What is the function of this protein?
Alpha2 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF (PubMed:9660828).  The activity and substrate specificity of PAF-AH (I) are affected by its subunit composition.  The alpha2/alpha2 homodimer (PAFAH1B2/PAFAH1B2 homodimer) hydrolyzes PAF and 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylethanolamine (AAGPE) more efficiently than 1-O-alkyl-2-acetyl-sn-glycero-3-phosphoric acid (AAGPA).  In contrast, the alpha1/alpha2 heterodimer(PAFAH1B3/PAFAH1B3 heterodimer) hydrolyzes AAGPA more efficiently than PAF, but has little hydrolytic activity towards AAGPE (By similarity).  May play a role in male germ cell meiosis during the late pachytenestage and meiotic divisions as well as early spermiogenesis (By similarity).
What are the official names of this protein?
Platelet-activating factor acetylhydrolase IB subunit alpha2, PAF acetylhydrolase 30 kDa subunit, PAF-AH 30 kDa subunit, PAF-AH subunit beta, PAFAH subunit beta, Platelet-activating factor acetylhydrolase alpha 2 subunit, PAF-AH alpha 2.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VVHA_VIBVU
Sequence: MKKMTLFTLSLLATAVQVGAQEYVPIVEKPIYITSSKIKCVLHTSGDFNATRDWCNAGASIDVRVNVAQMRSVQSATSDGFTPDAKIVRFTVDADKPGTGIHLVNELQQDHSWFQSWANRRTYIGPFASSYDLWVKPVSGYTPKKARDLPQNENKNYQHRDTYGYSIGINGKVGAEVNKDGPKVGGEVSGSFTYNYSKTLVFDTKDYRINNRSSLSDFDISFEREFGECDELRRQELGCYFTAAHWGSGWVFDKTKFNPISYSNFKPNYDVLYEAPVSETGVTDFEMGVKLNYRARFGTVLPSALFSVYGSAGSSTNSSTVKQRIRIDWNHPLFEAEAHVTLQSLSNNDLCLDVYGENGDKTVAGGSVNGWSCHGSWNQVWGLDKEERYRSRVASDRCLTVNADKTLTVEQCGANLAQKWYWEGDKLISRYVDGNNTRYLLNIVGGRNVQVTPENEANQARWKPTLQQVKL
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.
What are the official names of this protein?
Cytolysin.
What is the protein family that this protein belongs to?
Belongs to the HlyA hemolysin family.
Protein: ALBA_METS5
Sequence: MSGTSPTPSNVVLVGKKPVMNYVLAALTLLNQGVPEIIIKARGRAISKAVDTVEIVRNRFLPDKIEIRAIGVGSQVVTSQDGRQSRVSTIEISIKKKA
What is the function of this protein?
Binds double-stranded DNA tightly but without sequence specificity.  It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture.  However, it does not significantly compact DNA.  Binds rRNA and mRNA in vivo.  May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
What are the official names of this protein?
DNA/RNA-binding protein Alba.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: SUCC_BACP2
Sequence: MNIHEYQGKEILRKYGVSVPNGKVAFTPDEAVKASEELESSVYVVKAQIHAGGRGKAGGVKIAKTKDEVKGFAEELLGKTLVTHQTGPEGREIKRLLIEEGCDIQKEYYVGLVLDRATSRIVLMASEEGGTEIEEVAEKTPEKIVKVVIDPAIGLQGYQAREVAFKINIPTKLVGQAVKFMTSLYNAFIEKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRQKDILEYRDLDEEDPKEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGDPANFLDVGGGATAEKVTEAFKIILSDQNVKGIFVNIFGGIMKCDVIAEGVVEATKQVGLTLPLVVRLEGTNVELGKKILSDSGLNITSAESMADGAEKIVSLVK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RS8_AZOC5
Sequence: MSINDPIGDLITRIRNAQMRRKDKTSTPGSRLRASLLDVLRDEGYIRGYTTTDHGNGRTEFEIELKYFDGQPVIREITRVSKPGRRVYASVKALPRVANGLGIAVLSTPQGVMADHDARDKNVGGEVLCTVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RSMH_STRP1
Sequence: MTKEFHHVTVLLHETVDMLDIKPDGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIKDNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLTAYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKKIRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_EHRRG
Sequence: MIMMTRFAPSPTGYLHVGNVRTALICWLYTRSKQGRFLLRFDDTDLQRSKDDYRNEIANDLKWLQMDWDFDVRQSSRFDRYDEIFNYLLKEELIYPCYESKEELDFKRKMQLKLGLPPIYDRSALKLTQDEKNKYSEQDVYFRFKIDQSQLISWDDEIRGKVSFNAANISDPIVKRADGTYTYMLPSVIDDIDFDITHIVRGEDHISNTAIQIQMFNALRASVPTFSHLSLLYCDDNKISKRVGGFSIKDMQFYELEPMAINSYFAKIGTSDPIVVHTKIQDLIYNFDITKFNQAPTQFNIDDVIKLNPKVLHKMSFSDVKHRLSELNITSPDLWDFVSGNVQKFSDIQEWIKICGQSTVPVINESDQDFIKMALSVFPNGEINQDTWKTWVANIKEKTDRKSKDIFIPLRLALTGISTGPELAKLLPILGRAEIIRRLGYSSRC
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_HALLT
Sequence: MAGTIEALVPGGQATPGPPLGPELGPTPVDVQDVVAQINDETAAFDGMEVPVTVEYDDDGSFTIEVGVPPTAELIKDEAGFETGSGEPQVDFVADMSIEQVKKVAEQKSTDLLAYDVKNAAKEVGGTCASLGVTIEGEDARTFDDRVDAGDYDDVLDE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: LGT_BACAN
Sequence: MLLGSVPQLDRVAVQLGPFPVYWYGIIIGTGVLLGLWLATREGERLGIPKDTFVDLVLIAVPIAILFARMYYVIFEWEYYAQNPSQIINIRQGGLAIHGGLIGAVVTGILFAKRRGVSFWKLADIAAPSILLGQAIGRWGNFMNQEAHGDEVTRQFLEGLHLPDFIINQMYIDGVYYHPTFLYESLWNFAGVILLLALRKVNLRRGELFFTYLIWYSIGRFFVEGLRTDSLMLGPLRIAQVMSIGLVVISIIFIIVRRKMGQADKRYSEN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1604_PSEE4
Sequence: MDTKLLDILACPITKGPLKLSADKTELISKGAGLAYPIRDGIPVMLESEARTLTDEERLDK
What are the official names of this protein?
UPF0434 protein PSEEN1604.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: GUAA_STRPS
Sequence: MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHKISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGGKVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSADCPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKKIRKTVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLGGKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHIVWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: METE_SULIN
Sequence: MSKLPLLPTTVIGSYPRPKWLRESIRLHKAGKISDEDLQEAFSDAVIAVLKDHYNAGVDVPTDGEVRRDEMVEFFAERIKGFKFYGPVRVWGTAYYRKPSVVSKIEYKKPMLVDEFTFAKSVSYTDNLKITITGPYTIAEWSYNEYYKNKKDLVFDLAKAINQEIKNLVEAGAKIIQIDEPALHTRREDVSWGVEAVNEAVKGVNAKLVMHICYGEYSFVAPYLNELKVDQINFAFKIYNYKPLELLKRYGFDKELGAGVIDVHNRRIETSEEVANDIRKILEYFTPEKVWINPDCGLKLLSRKIAYQKLVSMVEGTKVVREELKRKGYSVD
What is the function of this protein?
Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation.  The physiological methyl donor is unknown.
What are the official names of this protein?
Methionine synthase, Homocysteine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal MetE family.
Protein: RL6_THEMA
Sequence: MSRLAKKPIVLPQGVTVEIKDNVVKVKGPKGELSQEFLPYVKIEVEGNEVWVRPNEEQIIRKSDWRKVKMFQGTYWSLIRNMVVGVTEGYKKELEIVGIGYRAQLQGNTLVMNLGYAHPVVYEIPSDVKIEVPAPNRIIVSGIDKQRVGQVAAEIRAFRPPNVYTGKGIRYVGEVVRQKEGKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: NTP1_MSEPV
Sequence: MHSIEHIVARHFNYALEKTKDLPKSINNEITNEIIILKDYQYLVSRIFIGLSELNSLLLFWDTGYGKTLTSVYIMKHLKLVFPQWFFVIFIKKSLYVDPWLNTLSKLGMKGQNIKFVLYDSSSSLKQFNVLYRTIISSINTKNRILIIIDEVHQVISRTIEKSSSTQRNFLSIFNKIVKLANSENNKLLCMSATPITNNVLEFKYLINLLRPKIIEFKEDFIVNNTLKNHEQLKNGLISITSYQKISEADSFTNTSYTEGFASKNIFYHNVTMTPEQSNIFNIADKHDKKSALGGLKTMRRLVSSFAFYDIKIKGSMSQIEYNKMVSEKLNEFKSIIGNFKFSNEFIDIFRNNDSFSNAKSSEIEIFDKIKQYSCKYIEACKIILNSNGKVLLYEPLVSFEGISTLKIYFNIFNISYVEYSSKTESTRDYNIDIFNKYDNLYGNKIKVCIFSAAGSEGISFSSINDIIILDLPWKESDIKQIIGRSIRLNSHEELPIEKRYVNVHFIIASTIDGKSVDKEIFDLIKSKQDKINVLNSFMKVISIEQIHSKYKYAEPVENEYIFNNIRHTKIDDVNENNVITKIIVSPIYYCSEDNLNIIYNGYLDKKTGIIYSNNIPIAKLILDENNIYKFFIKDDKLVYITKSIYE
What is the function of this protein?
DNA-dependent ATPase required for providing the needed energy to achieve the termination of early transcripts.  Acts in concert with the RAP94 subunit of the virion RNA polymerase and the capping enzyme/VTF to catalyze release of UUUUUNU-containing nascent RNA from the elongation complex.  NPH-I must bind ssDNA in order to exhibit ATPase activity (By similarity).
What are the official names of this protein?
Nucleoside triphosphatase I, NPH-I, Nucleoside triphosphate phosphohydrolase I, NPH I.
What is the protein family that this protein belongs to?
Belongs to the helicase family. NPH I subfamily.
What are the subcellular locations of this protein?
Virion. Note=Virion core enzyme.
Protein: CIMA_ARCFU
Sequence: MQVKILDTTLRDGEQTPGVSLSVEQKVMIAEALDNLGVDIIEAGTAIASEGDFQAIKEISQRGLNAEICSFARIKREDIDAAADAGAESIFMVAPSSDIHINAKFPGKDRDYVIEKSVEAIEYAKERGLIVEFGAEDASRADLDFVIQLFKRAEEAKADRITFADTVGVLSPEKMEEIVRKIKAKVKLPLAIHCHDDFGLATANTIFGIKAGAEEFHGTINGLGERAGNAAIEEVVIALEYLYGIKTKIKKERLYNTSKLVEKLSRVVVPPNKPIVGDNAFTHESGIHTSALFRDAKSYEPISPEVVGRKRVIVLGKHAGRASVEAIMNELGYKATPEQMKEILARIKEIGDKGKRVTDADVRTIIETVLQIKREKKVKLEDLAIFSGKNVMPMASVKLKIDGQERIEAAVGLGPVDAAINAIRRAIKEFADIKLVSYHVDAITGGTDALVDVVVQLKKDNKIVTARGARTDIIMASVEAFIEGINMLF
What is the function of this protein?
Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
What are the official names of this protein?
Putative (R)-citramalate synthase CimA.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: ANS4B_MOUSE
Sequence: MSTRYHQAASDSYLELLKEATKRDLNLSDEDGMTPTLLAAYHGNLEALEIICSRGGDPDKCDIWGNTPLHYAASNGHTHCISFLVNFGANIFALDNDLKSPLDAAASREQKECVALLDKAATVQNTMNPKRVTRLKEQALKNARKQMKECERLQERHQNKMARTYSKEDSGTISSSHSTLSRSFLSTTSAGRFGSLSKGIKDTFKIKSKKNKDTTEQLEKDGRSGQRPVMEVFREEEEDSFPKDFKEKLHFSVEEDDDVQHESILNRPGLGSIVFSRNRVLDFEDISDSKRELGFKMPSELFQRQGAAGTVEEEEEEEEEEEEEKREANGTAGDLPWDEEEVEWEEDAVDATPLEVFLQSQHLEEFLPIFMREQIDLEALLLCSDEDLQNIHMQLGPRKKVLSAIDKRKQVLQQPGQLVDTSL
What is the function of this protein?
As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length.  Plays a role in assembly of the complex (By similarity).  May play a role in cellular response to endoplasmic reticulum stress (PubMed:22589549).
What are the official names of this protein?
Ankyrin repeat and SAM domain-containing protein 4B, Harmonin-interacting ankyrin repeat-containing protein, Harp.
What are the subcellular locations of this protein?
Cell projection, microvillus. Note=Localizes at the tip of microvilli (PubMed:26812018). May associate with endoplasmic reticulum membranes (PubMed:22589549).
Protein: NU4M_AGKCO
Sequence: PIAGSMVLAAILLKLGGYGIIRMMQILPTTKTDMFLPFVVLALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIIIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILILTRGLHNILPMATTWWLLTNLMNIAVPPTMNFTGELLIMSALFNWCPTTIIMLGLSMLITASYSLHMFLSTQMGPTLLNNQTEPTHSREHLLMILHLIPLMMISMKPELVI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SUB4_TRIVC
Sequence: MVCLKTLSVFLAAFAAADARAVFKTQGHKNSEMIPDNYIVVMKDGVSQDDFKAHISSVASIHSTNKAKRGTNTQGMKREFDIMNWRGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRSAPSWGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDNADRHGHGTHTASTFAGTAYGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQDAQQRGILGKAAMNLSLGGGFSQANNDAVTRAQNAGIFVAVAAGNDNRDARNYSPASAPAVCTVASSTINDSKSSFSNWGPVVDIYAPGSDIIAARPGGGSTTMSGTSMASPHVAGMGAYMIGMGADPRQVCDRLKQLATAAIRNPGSSTTNRLLYNGSGQ
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.