PharMolix/UniProtQA huggingface dataset:
Protein: MNMC_PSEA7
Sequence: MSDFQHAQLDWDENGQPLSRVFGDVYFSRHSGLDETRHVFLATNRLAERFAALGDGEALCIGETGFGTGLNFLCAWQLFERVAPPGARLEFVSVEKFPLAAADLRRALALWPELAPWSEPLLGQYLALHPGFQRLAFAGGRVGLTLLLGDALECLPQLDARIDAWFLDGFAPAKNPDMWSPALFAELARLSAPQATLGTFTSAGFVRRGLIEAGFAMQRVPGYGQKREMLGGTYQGPPASAGKPWYARPAPHAGRRAALVVGGGLAGCASAASLAARGWQVTLIERHPGLAREASGNPQGVLYLKLSAHGTPLSRLVLSGFGHTRRLLERLRRGHDWDACGVLQLAFDAKEAQRQAQLAAAFPADLLHGLDREQAERLAGVALPAGGLFYPEAGWVHPPALCQALATTPGITLLSGRAVRLRREGDDWCAYAGDECLARAPLAILATAADIRDFPPAAELPLKRIRGQVTRLPATAQSRALRTVVCAEGYVAPPRGDEHTLGASFDFKSEDLAPTLAEHQGNLELLREISPDLLQRLGADDLPLERLEGRAAFRCTSPDYLPLVGPLAERAAFDEAYAVLARDARQVPERACPWLPGLYLNSGHGSRGLISAPLSGELLAAWICGEPLPLPRAVGEACHPNRFLLRDLVRGQRG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_PICTO
Sequence: MARSKISVIGAGAVGATVAQTLAIRQTGDIYIFDIVDGLAEGKALDILEGAPHWGYDLDIKGFCTADESKYAEMKGSDVIVVTAGLARKPGMSRDDLLLKNIGIMKSVGEAIKKYSPESKIVVVTNPADIMAYAIYKASGISPERIIGLGGSLDSTRFRTFLAQELNVSFEDVNAFVIGGHGDDMVPFIRYSNVSGIPIEDLLPREKIDEIVKRTRFGGGEIVNLYKTGSAFYAPGISIAVMVESIVNDRKRVIPCAAYITGEHSKTYLVNNLFIGVPIKIGKNGVEKIYDLKFNEDELEAWKKSVESVKKNSAIADDYFAKNQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: LYS1_CRAVI
Sequence: MNGLILFCAVVFATAVCTYGSDAPCLRAGGRCQHDSITCSGRYRTGLCSGGVRRRCCVPSSSNSGSFSTGMVSQQCLRCICNVESGCRPIGCHWDVNSDSCGYFQIKRAYWIDCGSPGGDWQTCANNLACSSRCVQAYMARYHRRSGCSNSCESFARIHNGGPRGCRNSNTEGYWRRVQAQGCN
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacteria L. garvieae, M. luteus and Enterococcus sp. , and the Gram-negative bacteria E. coli and V. vulnificus.  Weak antibacterial activity against the Gram-negative bacterium A. hydrophila.  No antibacterial activity detected against the Gram-positive bacterium S. iniae or against the Gram-negative bacterium E. ictaluri.  Shows some chitinase activity but no isopeptidase activity.
What are the official names of this protein?
Lysozyme 1, 1,4-beta-N-acetylmuramidase 1, Invertebrate-type lysozyme 1, cv-lysozyme 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family. Type-I lysozyme subfamily.
Protein: TATA_GEOMG
Sequence: MFGIGMPELIVILVIVLVVFGAGRLPEIGGALGKSIRNFKKASDGKDEIEIKPEKKDDPSK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PURNU_STAAW
Sequence: MNDNFKKQPHHLIYEELLQQGITLGITTRGDGLSDYPKNAFNMARYIDDRPYNITQHQLQLAEEIAFDRKNWVFPIQTHENKVACITKDDIGTNIDTLTDALHGIDAMYTYDSNVLLTMCYADCVPVYFYSTKHHFIALAHAGWRGTYTEIVKEVLKHVNFDLKDLHVVIGPSTSSSYEINDDIKNKFETLPIDSANYIETRGRDRHGIDLKKANAALLNYYGVPKENIYTTAYATSEHLELFFSYRLEKGQTGRMLAFIGQQ
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase MW1070, Adenosine deaminase MW1070, S-methyl-5'-thioadenosine phosphorylase MW1070.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: RIMM_AQUAE
Sequence: MMEEYVVIGKVLDTFGLEGELKVRPYAPPEVFENLEKVYLKRKGGDWVPFEVEWVDFIDDKVIIKFKGYDSIDEVEQFKGAKLFLPKEELPELGEEEYYAYELVGMEVETDKGKKLGKVERVQDMGPYDALVLDKENLLVPFVSDIVLKVDKENKKIIVKEELLPV
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_RHOE4
Sequence: MALTTEEKKVVLGEYGLHETDTGSPEAQVAMLTKRITDLTEHLKTHKHDHHSRRGLLLMVGRRRRLLKYVAKTDVARYRTLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MTPS2_PINBN
Sequence: MALVSAVPLDSRLCLCRTLFGLTHELKAIRRTIPNLGMCRGGKSIAPSMSMSSTTFVSSEDGVPRRIGGHHSNLWDDDSIDSLSTSYEAPSYRERADRLIGEVKDMFHLISVEDGVSTSPLNDLHHRLWMVDSVERLGIDRHFKNETNAGLDHVYSYWTEKGIGRGRESGATDLNSTALGLRTLRLHGYMVSSHVLDHFKNEKGQFTCSAIQTEGEIRDVLNLFRASLIAFPGEKIMDAAEIFSTMYLKDALQKIPPSGLSQEIEYLLEFGWHTNLPRMETRMYIDVFGEDTTFETPYLIRERLLELAKLEFNIFHSLVKRELQSLSRWWKDYGFPEITFSRHRHVEYYTLAACIANDPKHSAFRLGFAKICHMVTILDDIYDTFGTMEELELLTAAFKRWDPSSIECLPDYMKGVYMAVYDNINETAREAQKIQGWDIVSYARKSWEALFDAHMQEAKWISSGYLPTFEEYLENGKVSFGSRLTTLEPMLTLGFPLPPRILQEIDFPSNFNELICAILRLRGDTQCYKADRARGEEASSVSCYMKDHPGITEEDAVNQINALVNNLTKELNSELLRPDSGVPISYKKFYFDIWRVFHYGYKYRDGFSVASIEIKNLVTITVVETVPL
What is the function of this protein?
Monoterpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens.
What are the official names of this protein?
Monoterpene synthase like 2, chloroplastic, PbTPS-mono2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2874_CLOAB
Sequence: MKQIKVISIFGTRPEAIKMAPLVRRLNENKNVESKVCVTAQHRQMLDQVLNLFDINPDFDLNIMKTKQTLTGITARVLEGLDKIFADENPDIVLVHGDTTTTFAAALAAFYKKIAVGHVEAGLRTYNKYFPFPEEMNRKLTGAVADLHFAPTLGSKKNLLREAVNEKNIFITGNTVVDAMNHTVEKDYVFENDELNKLDYKNKKVIMVTAHRRENWGKGIENICTALRRIAEENEDVEIVYLVHLNPVVKDVVYNNLNGMKGVHLLPPLDTKETHNLMNKCFMVMTDSGGLQEEAPHLGKPVLVLRDVTERPEAVEAGTVKLVGTDIKKIVDEAYKIMKDEEEYEKMSKAINPYGDGKASDRIVDAILYHFGVLKDRPDEFSPKK
What are the official names of this protein?
Putative UDP-N-acetylglucosamine 2-epimerase, UDP-GlcNAc-2-epimerase.
What is the protein family that this protein belongs to?
Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_STAAW
Sequence: MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFDVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVDGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQTSDVYRKIRNTLRFMLGNINDFNPDTDSITESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH_RICTY
Sequence: MAEFTPITIAYGDGIGPEIMDAVLYILRQAEARISLETIEVGEKLYKKHYTSGISEESWNVIQRTGIILKAPITTPQSGGYKSLNVTIRKTLQLFANIRPAVSFHPFTRTLHPNLNLTIIRENEEDLYSGIEYRQTHNMYESLKLISHTGCKKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGIFHRVFNEIAKEYPQIDNEHYIIDIGTAKLATTPEIFDIIVTSNLYGDIISDVAAEISGSVGLAGSANIGQHYAMFEAVHGSAPDIAGKGIANPSGLLNAAIMMLVHIGQGDIASLIENAWKKTIEDGVHTFDIYSEHSSSKKVCTKEFAEEVIKRLGQLPMTLPKASYPLIVKKQESKIEYKIDTTEVKKLVGTDIFINIHVFSAHDIADKINKLDIGNFELKTISSKGLKLWPHDLRFEIISDHWCCRFMNKDGTEIKHLDIIILLQALSKANIDFIKVENLFEFDGVACYSLAQGE
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: NUON1_NITOC
Sequence: MSSLDFTALLPLILITLASLTLTLIVAGYRQHRLTMVATLIALVLCLAVIPLAAAVSPQHVPPLFIIDRYALFYMGLIFTAALAITLLAYGYMKGLVDQPEEFYVLLLLASLGAAILAASNHFASLFLGLEILSVSLFALLAYPRRFQLSLEAGVKYLILSSASSALLLFGMALIYAETGALGFGQLSTLLSTGALSSEIFFLAGLALIMTGLGFKLSWVPFHLWAADVYQGAPAPVTAFLATVSKGAVFALLLRLFVQVDGPQHHTLIVLLSFIAVATILAGNLLALLQNNIKRILAYSSIAHLGYLLVALLASGNLGVEAVTFYWVAYFIMNLGAFGVVTVLSSPTQEKENLEDYRGLFWHRPGLAGIFTFMLLSLAGIPLTVGFIGKFYIFAAGVEATLWLLLFTFVMGSILGLFYYLRIIIALYQTPTIEKEALASPSSLPLMGSLTLALLTLLLIWWGVYPDPLMRIIQAVAMALI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 1, NADH dehydrogenase I subunit N 1, NDH-1 subunit N 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSLO_COLP3
Sequence: MSQFNVLNRYLFTDAHARGELVQLSSSFESIIKNHNYPVGVEKLLGELLCATCLLTATLKFEGDITVQLQGDGPVGYMSVSGNNKQQMRGIAKMAEETSADTLQTLIGKGTMIITIRPNAGEAYQGVVALDEESLADCLAHYFDVSEQIPTKIWLFCDTEQQLAAGALVQLLPDGDGSTENKEQQQSDFEHLCQLTNTIKSEEVFSLEAEALLYRLYHQEQVNIFEPQMVSYLCGCSADKCLSAISQIEPSEIKAILAEHGKISMTCDYCITTYDFDELSLKSFISKVNH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGP5_ARATH
Sequence: MASKSVVVFLFLALVASSVVAQAPGPAPTISPLPATPTPSQSPRATAPAPSPSANPPPSAPTTAPPVSQPPTESPPAPPTSTSPSGAPGTNVPSGEAGPAQSPLSGSPNAAAVSRVSLVGTFAGVAVIAALLL
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.
What are the official names of this protein?
Classical arabinogalactan protein 5.
What is the protein family that this protein belongs to?
Belongs to the classical AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: MED10_USTMA
Sequence: MSSTAGTRRPRQITPTSPSPSPEPQPGATNGSSSTINVAVPSASAPAQVAPSQVAAAAATPVDAAEAVRINLETRVRSVVDLLYQLAVCSADVQEGSQHLVANKVNECIQALAALDATKDELHRAHMMIPQDVLEMLDTGKNPDIHTRNFVNRLASENQYSYGQHRAVERYKATLDAALDQAFPELKAAQAESTETK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 10, Mediator complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL28_CAMLR
Sequence: MSRICQITGKGPMVGNNVSHANNKTKRRFLPNLRTVRITLEDGTTRKVRVAASTLRTLKKQSSK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DHAA_MYCBO
Sequence: MTAFGVEPYGQPKYLEIAGKRMAYIDEGKGDAIVFQHGNPTSSYLWRNIMPHLEGLGRLVACDLIGMGASDKLSPSGPDRYSYGEQRDFLFALWDTLDLGDHVVLVLHDWGSALGFDWANQHRDRVQGIAFMEAIVTPMTWADWPPAVRGVFQGFRSPQGEPMALEHNIFVERVLPGAILRQLSDEEMNHYRRPFVNGGEDRRPTLSWPRNLPIDGEPAEVVALVNEYRSWLEETDMPKLFINAEPGAIITGRIRDYVRSWPNQTEITVPGVHFVQEDSPEEIGAAIAQFVRQLRSAAGV
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: DPO1_SALTY
Sequence: MVQIPENPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQYQPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLLAVSGVEADDVIGTLAREAEKVGRPVLISTGDKDMAQLVTPNITLINTMTNTILGPDEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLTFRGAKTMAGKLAQNKDVAYLSYKLATIKTDVELELTCEQLEVQQPIADELLGLFKKYEFKRWTADVESGKWLQAKGAKPAAKPQETVVIDESPSEPAAALSYENYVTILDDVTLESWIEKLKKAPVFAFDTETDSLDNIAANLVGLSFAIEPGVAAYVPVAHDYLDAPDQISRQRALELLKPLLEDEKVRKVGQNLKYDRGVLQNYGIELRGIAFDTMLESYILNSVAGRHDMDSLSDRWLKHKTITFEDIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPELQQHKGPLNVFENIEMPLVPVLSRVERNGVKIDPAVLHKHSEEITLRLAELEKKAHDIAGEAFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYLIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLDSVTGEQRRSAKAINFGLIYGMSAFGLSRQLNIPRKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLEGRRLYLPDIKSSNAARRAGAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDLDAVAKRIHQLMENCTRIDVPLLVEVGSGENWDQAH
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.  It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: NRAM_I02A1
Sequence: MNPNRKIITIGSICMVIGIVSLMLQIGNIISIWVSHSIQTENQHQAEPISNTNFLTEKAVASVTLAGNSSLCPISGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPHRTLMSCPVGEAPSPYNSRFESVAWSASACHDGTSWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQASYKIFKMEKGKVVKSVELDAPNYHYEECSCYPDAGEVTCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGVFGDNPRPNDGTGSCGPMSLNGAYGVKGFSFKYGNGVWIGRTKSTNSRSGFEMIWDPN
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane (By similarity).
Protein: KDSA_VEREI
Sequence: MKLCGFDVGLEQRLFLIAGPCVIESAQLQMDVAGQLREITARLGMPFIFKSSFDKANRSSGSSYRGPGRDKGLEILARVRRELALPVLTDVHTEDDIAAAAQVVDVLQTPAFLCRQTDFISAAARCGKPVNIKKGQFLAPHEMHNVIDKARAAARQAGLSEDRFMACERGASFGYNNLVSDMRSLAIMRASGAPVVFDATHSVQLPGSQGSRSGGQREMVPVLARAAVAAGVAGIFMETHPDPDRALSDGPNAVPLKHMQALLETLVALDGVTKRHGFLENRFGA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NH154_CAEEL
Sequence: MTTFEEFESPSTSFNFQTFDRYQPDFKMIDYSHQQATHEYHLPDQEVFQNQNEFSASPPDISSPFADEKIYKSLPRNKCPSKCLVCRNPAIGYHYDVPSCNGCKTFFRRTIITGRKFTCAKQKKCMDGTEPVDMSKRLCRACRFAKCVEVGMNPMAIQAEVKTDEGKVLRSEVLNQRESLGVVSSLIVTEEDLLSRMIEKLTFVESKVEPLHRSGMPPGYRDIRKLEEILDSKPVLVVTDIPNLKFCPSPCANEKRPRRHFTNYVHTSYLASLESSKMFEFSSQLDLESRILLMKHATLICSNMMNAFFSINEMKSDILRHPDGSMSGHMRKFDRENDVMTDHVKLIQKTLITFLNHKVDKIEYLLFKAIMLCNPAVPGLDSWNQEIIEKERNQYVKALLNYCLLQHGKLQGPTRFATILAMAPIIENQSKNQKDFHVYIKAKHFQKHKKMGTTFRKCISCMFDQIMET
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-154.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KATG_BURMS
Sequence: MSNEAKCPFHQAAGNGTSNRDWWPNQLDLSILHRHSSLSDPMGKDFNYAQAFEKLDLAAVKRDLHALMTTSQDWWPADFGHYGGLFIRMAWHSAGTYRTADGRGGAGEGQQRFAPLNSWPDNANLDKARRLLWPIKQKYGRAISWADLLILTGNVALESMGFKTFGFAGGRADTWEPEDVYWGSEKIWLELSGGPNSRYSGDRQLENPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGAEPEAAGIEAQGLGWKSAYRTGKGADAITSGLEVTWTTTPTQWSHNFFENLFGYEWELTKSPAGAHQWVAKGADAVIPDAFDPSKKHRPTMLTTDLSLRFDPAYEKISRRFHENPEQFADAFARAWFKLTHRDMGPRARYLGPEVPAEVLLWQDPIPAVDHPLIDAADAAELKAKVLASGLTVSQLVSTAWAAASTFRGSDKRGGANGARIRLAPQKDWEANQPEQLAAVLETLEAIRTAFNGAQRGGKQVSLADLIVLAGCAGVEQAAKNAGHAVTVPFAPGRADASQEQTDVESMAVLEPVADGFRNYLKGKYRVPAEVLLVDKAQLLTLSAPEMTVLLGGLRVLGANVGQSRHGVFTAREQALTNDFFVNLLDMGTEWKPTAADADVFEGRDRATGALKWTGTRVDLVFGSHSQLRALAEVYGSADAQEKFVRDFVAVWNKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: IRAM_SALPA
Sequence: MEWKVVDTVISPSTGVSFSCIHSLKNLRLTLWYQADVYMPPGSIIIPFNKGVLINDKLYPVTVYNVTRFNPVLWKSLKENSHCPGNCNPKPEACSYPFECLVSVCPFGLTRNIQIDNKKV
What is the function of this protein?
Involved in the stabilization of the sigma stress factor RpoS.
What are the official names of this protein?
Anti-adapter protein IraM, Sigma S-regulator RssC.
What is the protein family that this protein belongs to?
Belongs to the IraM/RssC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y932_PSEPW
Sequence: MPQASPTSAGHAAENQALEFLQGQGLRLLTRNWRCKGGELDLVMLDTDTVVFVEVRYRLHAGFGGALGSIDGRKQKRLVHAASLFLLKESCWANHPCRFDVVALQGSHHAGRPLQWLKNAFEC
What are the official names of this protein?
UPF0102 protein PputW619_0932.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: HSLV_SALPK
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELGAREIAEKALDIAGDICIYTNHFHTIEELTAKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_ALKMQ
Sequence: MKTNELRDMTDVELNQKLSDLKSELFNLRFQLATGQLENPLRIRNVRKDIARLKTILRENELKQVRA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.