PharMolix/UniProtQA huggingface dataset:
Protein: PSAA_CHLAT
Sequence: MTISPPEQEASVKIVVDRDPVKTSFERWAKPGHFSRTLAKGPNTTTWIWNLHADAHDFDSHTNDLEDISRKVFSAHFGQLAVIFIWLSGMYFHGARFSNYEAWLSDPTHIKPSAQVVWPIVGQEILNGDVGGGFQGIQITSGFFQLWRASGITSELQLYSTAIGGLVMAGLMLFAGWFHYHKAAPKLEWFQNVESMLNHHLAGLLGLGSLSWAGHQIHVSLPINKLLDAGVDPKEIPLPHEFLVNRDLTAQLFPSFAKGLTPFFTLNWAEYSDFLTFKGGLNPVTGGLWLTDTAHHHLAIAVLFLVAGHMYRTNWGIGHSIKEILEAHKGPFTGAGHRGLYEILTTSWHAQLAINLALFGSLSIIVAHHMYAMPPYPYLATDYGTQLSIFTHHTWIGGFCIVGGAAHAAIFMVRDYDPTNNYNNLLDRVIRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHYLAPNLTAPNALAPTSATWGGDVVAVGGKVAMMPISLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKVNLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSLSIAIFHFSWKMQSDVWGSVTAKGVSHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSALSAYGLMFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIIQGRAVGVAHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NTRB_RHILP
Sequence: MTKDTTSPPDQAGGTVAMAVLNAIQNPVVMVDESGFIAFANWEAEAFFGAAFASGALPDLDIHSFGSPLLALVDQVRTQGSPVNEYRVDLSSPRLGQDKLVDLYVAPVLSEPGGVVIVFQERSMADKIDRQLTHRAAARSVTGLASSLAHEIKNPLSGNRGAAQLLEQSVIDDDRALTRLICDETDRIVSLVDRMEVFSDERPVRRMPVNIHSVLDHVKRLAQSGFARNIRITESYDPSLPAVYANRDQLVQVFLNLVKNAAEAVGDRPDGEIMLTTAYRPGIRLSVAGTREKISLPLEFCVHDNGPGVPADLLPHLFDPFITTKTNGSGLGLALVAKIIGDHGGIIECDSQNSRTTFRVLMPASKDASLEDASSASSTGPSR
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Under conditions of nitrogen limitation, NtrB autophosphorylates and transfers the phosphoryl group to NtrC.  In the presence of nitrogen, acts as a phosphatase that dephosphorylates and inactivates NtrC.
What are the official names of this protein?
Sensory histidine kinase/phosphatase NtrB, Nitrogen regulation protein NR(II), Nitrogen regulator II, NRII.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_STAEQ
Sequence: MIYGIGIDLIEIERIKNLQNQTKFIERILTIEERDKLNQYTHEQRRLEFLAGRFTVKEAFSKALGTGLGKSVSFQDINCYNDALGKPCIDYPGFYTHVSITHTENYAMSQVILEKNE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_SHESH
Sequence: MKFYLVGGAVRDNLLNLTVKDRDHMVVGATPQQMLEMGYRQVGKDFPVFLHPETGQEYALARTERKTGVGYGGFSCHASPDVTLEEDLLRRDLTINAIAQDEEGQLYDPYGGVDDINNRVLRHVSDAFVEDPLRVLRVARFAARFHRQGFTIADETLAMMTQISHSGELEALTAERVFLELDKALATDSPQVFIHVLNQCDALAILFPEIHALFGVPQPVKWHPEIDTGIHTLMVLEQAAKLCDDNSVRFAALVHDLGKALSPKEHLPKHHGHGQKGLALIKVLCARVRVPNDYRDLALLVSDLHQNIHQIEELRPDTLVKIFDKADLWRKPERLEQIALACEADAKGRLGQEEWSYPQADYFKQCFMAANKVAVKPIIEAGFKGAEIKAQLQLKRIEAVAEIKQNLNQTDSP
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: FUMC1_PSEAE
Sequence: MSRTETDSLGTIEVPDDAYWGAQTQRSLENFAIGGQRMPLAVIHALALIKKAAARVNDHLGELPPEVARLIEQAADEVLAGRHDEHFPLVVWQTGSGTQTNMNVNEVIAGRANELAGNPRGGKSPVHPNDHVNRAQSSNDSFPTAMHIAAAKAVHEQLLPAIAELSGGLAEQSARHASLVKTGRTHLMDATPITFGQELSAFVAQLDYAERAIRAALPAVYQLAQGGTAVGTGLNAPKGFADAIAAEIAAESGLPFVAAPNKFAALAGHEPLVILSGALKSLAVALMKIANDLRLLGSGPRAGFAEVKLPANEPGSSIMPGKVNPTQCEALSMLACQVMGNDSTISFAASQGHLQLNVFKPVIVYNLLESIRLLADGCRNFNKHCVAGLEPDAQRMADLLERGLMLVTALNPHIGYDKAAEIAKKAYAEGTTLRAAALQLGYLDEAQFDEWVRPEQMLEAGHHG
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II 1, Fumarase C 1, Aerobic fumarase 1, Iron-independent fumarase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPPA_YERPS
Sequence: MMLSSTSLYAAIDLGSNSFHMLVVREVAGSIQTLARIKRKVRLAAGLDNQNHLSQEAMERGWQCLKLFSERLQDIPLDQIRVVATATLRLASNADEFLRTATEILGCPIQVISGEEEARLIYHGVAHTTGGPEQRLVVDIGGGSTELVTGNGAQANILVSLSMGCVTWLERYFGDRHLAKENFERAELAAHEMIKPVAQRFREHGWQVCVGASGTVQALQEIMVAQGMDELITLAKLQQLKQRAIQCGKLEELEIPGLTLERALVFPSGLSILIAIFQELSIESMTLAGGALREGLVYGMLHLPVEQDIRRRTLRNLQRRYLLDTEQAKRVSCLADNFFLQVEKEWHLDGRCREFLQNACLIHEIGLSVDFKHAPQHAAYLIRNLDLPGFTPAQKLLLSALLQNQSDTIDLSLLNQQNALPADMAQHLCRLLRLAIIFSSRRRDDTLPAVRLRADNNALYVLVPQGWLEQHPYRAEALEQESHWQSYVQWPLLLEELS
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: HBEAG_HBVA2
Sequence: MQLFHLCLIISCTCPTVQASKLCLGWLWGMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGNNLQDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.  This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein, p25.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: VF424_ASFP4
Sequence: MSNYYYYYGGGRYDWLKTVEPTNFLKIGLPYQAHPLHLQHQATTPPSILEKFKRADILLNEVKAEMDPLMLQPETEKKLFQILSSIDMFKGLRKKVEFTYNAQIVTNAWLKMYELLNTMNFNNTSQAFCNCELPGGFISAINHFNYTMMHYPTFNWVASSLYPSSETDALEDHYGLYQCNPDNWLMQSPLLKKNMDYNNGDVTIASNVKNLALRATQRLTPIHLYTADGGINVGHDYNKQEELNLKLHFGQALTGLLSLSKGGNMILKHYTLNHAFTLSLICVFSHFFEELYITKPTSSRPTNSETYIVGKNRLRLFTPKEEQVLLKRLEFFNDTPLVDLSLYQNLLESVYFAVETIHLKQQIEFLNFGMKCYRHFYNKIKLLNDYLAPKKKIFQDRWRVLNKLYVLEKKHKLKLCAASQGSVA
What are the official names of this protein?
Probable methyltransferase EP424R, pEP424R.
What are the subcellular locations of this protein?
Virion.
Protein: ANMK_CHESB
Sequence: MEPAWAIGLMTGTVLDGNIDIAMIRTDGEKVDAFGPYKLAPYPPELPILLGRALEEAAKWRFQGQEPAIFREAEAALTQAQALAVCDFLRENGLSPGDIKAIGFHGQTVLHIAPKDGRRGHTRQLGDGPLMAKIVGADVVYDFRTADVEAGGQGAPLVPIYHRALLDRIGGGCETAMLNLGGVGNISWFDGDQMVAFDTGPANAPINDWVKRHGRGNFDTDGRIALSGTVDEARLSRLLDHPYLNAPYPKSLDRNSFTADMAEGLSLENGAATLTAFSAAAVGRALDLLPERPNRLLVCGGGRKNPALMAQLRRRANVQAMDVDQFGMRGDAIEAECFAFLAVRSIRGLPISFPQTTGVSKPMSGGRLAPASARNAA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RIR2_MYCPN
Sequence: MANTKKYFLESVSPLEYAQKKFQGNLRSVNWNLVDDEKDLEVWNRITQNFWLPEKIPVSNDIPSWKQLSKEWQDLITKTFTGLTLLDTIQATIGDIKQIDYALTDHEQVIYANFAFMVGVHARSYGTIFSTLCTSEQITEAHEWVVKTESLQKRAKALIPYYTGKDPLKSKVAAALMPGFLLYGGFYLPFYLSSRKQLPNTSDIIRLILRDKVIHNYYSGYKFQRKVEKMSKEKQAEMKRFVFDLMYELIELEKAYLKELYEGFGIVEDAIKFSIYNAGKFLQNLGYDSPFTEEETRIKPEIFAQLSARADENHDFFSGNGSSYVMGISEETEDKDWDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit beta, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: DUT_SALAR
Sequence: MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDGAVELAPGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL7A_THEAC
Sequence: MEKSYVKFETPEDVSQKALDLVESSYRTGKVKKGTNEVIKSIERGESKLVVIAEDVNPPEVVYYLPSLCEDKKVPYVYVKKKADLGSKVGIASAASVSIVDYGKNEELYKSIVSALEQIKK
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_MESM1
Sequence: MEKIYNHKIVEKDKNEKWIKKEYFSTHDLTKKPFSILLPPPNVTGKLHIGHAWNTTLQDFLIRLKRLQGYDVLWLPGTDHAGIATQAKVEKRLLDQKIFKSDLTKEELFEKAMDWKNEYANEIKKQWSKLGLALDYKKERFTLDELSNKAVNDIFVMLYKDGYIYRGNRAIYYDTFLQTSLSNIEVINVEKESKMYYLKYFLENSNSEYVLVATTRPETLASDVALIINPNDKKNSHYLGKNFVNPLTKKIIKMHSDDYAIMNFGSGIVKISAHDMNDFDVIKRLNLEVIETIDKFGKMTNAIPEFENMSSLEARENIVLKLKKENLIDKIENIKSNIIMSERSNTVAEVLVMPQWFIKMEPFSKMILKKIQNENEDDKKVLFFPKKFENILKIWMQEAHDWNISRQLWWGHKIPAWYDEKGNIKVQTTSPGSNWTQDQDVLDTWFSSGIAPFSFLNWPQKSEFLKRYYPTSVIVTAYDIIFFWVARMYFMGIYSMKNIPFKKALIHGLIRDEQGRKMSKSLGNGIDPMDLIEKYGADSLRWFLMTNSTPGQDIRFNYDKIESAWSLINKIWNISRYIKMLDSDKKEIIPEEIEQNANSWILEKFENLKILIYEKSETFEFSVIGKEIFKFINEDFSSVYIEIIKGTDSKEFISKIWSNFLILLHPFLPFLTDHLYFELNKKELLESDFFELKSRKNNLFIDETIEIISTLREYRTRFNLSHKIDLNYNLVSINNSNQCDFNLDLKKYLIKKMANANFSENGQIFFKLNNYELRLQIPEEVKKEEETIRIKRILFLESEIKRSQSILSNEKFINNASEIKVKEEKEKLEKYIKEFEEIK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
Protein: RSC7_YEAST
Sequence: MSDSEGGLASEVEHEKRSRSTSNRPNYAIDTEDLDIDENDENEDDDYREEEANEGVNEEEISDEEEQINKSGRNKRRHVDEEEDLSEDKGVTRSRNRSKFKKPVFPGIDDAEENLNPLKVVNEEYVLPDDPEGETKITADGDLLGGREFLVRTFTLTEKGNRKFMLATEPARIVGFRDSYLFFQTHPNLYKFILNQTQKNDLIDRGVLPYSYRNRQIALVTARGVFKEFGAKIIRGGKHITDDYYASELRTKGNVIEGKLAGDPIDKSARALETMMYPASENGINPAKNQVEFFEHRPHGHMSNSNIIASGSKLSSTNWLYQHSAACSRFNSDLFYDRVKVLLVDQQGLRDAYTNILHIPESTQSTTVLGWRRSKNDSPSDTSIVYETVIHDNDLNKPKTGLSEIPKEIYEDVVDEDVLRAITEQQNFEKCNEYI
What is the function of this protein?
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA.  The reaction requires ATP and involves an activated RSC-nucleosome intermediate.  Remodeling reaction also involves DNA translocation, DNA twist and conformational change.  As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.  Together with HTL1, LDB7, RSC3, RSC30 components, defines a fungal-specific module within the RSC complex that plays a role in many cellular functions including the maintenance of cell wall integrity.  Acidic protein important for nuclear protein localization.
What are the official names of this protein?
Chromatin structure-remodeling complex subunit RSC7, Nuclear protein localization protein 6, Remodel the structure of chromatin complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the RSC7/SWP82 family. RSC7 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPNP_PSEPK
Sequence: MFQVNEYFNGTVKSIAFSGEEGPATVGVMAPGEYEFGTAKREIMHVVSGALTVKLPGSDNWETFNAGDKFNVPADSKFQLQVKVDTAYLCEYRD
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: TRMB_PSET1
Sequence: MSESSNTNLEQAKQEGKYIRTIRSFVKREGRLTKGQAAAIEKCWPIMGLEHKNGMLDLSEVFGNNNDVVLEIGFGMGKSLVEMAKNAPHLNFIGIEVHRPGVGACLMDADEAGITNLRIFEHDAVEVLADCIADESLTTLQLFFPDPWHKKRHHKRRIVQGEFVEKLRSQLKMGGVFHMATDWENYAEHMLEVMQAAPGFKNQSTTNDYVPRPDLRPLTKFEQRGHRLGHGVWDLMFERTK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RS16_HERAR
Sequence: MVVIRLARGGAKKRPFFNIVATDSRNRRDGRFIERIGFYNPVASGAEESVRIAQDRLAYWQGVGAQLSPTVARLVAQAGKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TRUD_YERP3
Sequence: MDMENLTWLHGKPTASGILKANPEDFVVVEDLGFEPDGEGEHLLVRIRKNGCNTQFVADYLARFAKLHPRLVSYAGLKDRHAVTEQWFCLHLPGKEAPDLATFELEGCEVLEAVRHKRKLRIGSLKGNAFTLVLRHITDRQDVEQRLQQIAAQGVPNYFGSQRFGRGGNNLVQARLWANNEIRVKERSKRSFYLSASRSAMFNLISSHRLAQQLSTTVLEGDALQLSGRGSWFVAQADELATLQQRVTAGELNITAPLPGDSELGTHGEALAFEQACLAEQTELLSLIKRERVEGSRRAVLLKPQNMISNWWDDVTLELSFWLPAGSFATSVVREIMNQDRADDTDIIE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: ILVD_ANASK
Sequence: MRSDRIKKGFERAPHRSLLRATGLNDGDFEKPFIGIANSHIDIIPGHYYLQEYGRIAKDEIRKAGGVPFEFNTIGVDDGIAMGHEGMKYSLPSRELIADSIETVMNAHQLDALVCIPNCDKIVPGMLMGALRVNVPTVFVSGGPMKAGHLHDGTPIDLNTAFEAVGKRAQGQLTDAELYEIECQACPSGGSCSGMFTANSMNVLCEAMGVALPGNGTVLALTPEREALVRRAARRAVEIAADERFKLRNIANRDAIHNAMVVDMAMGGSSNTVLHMLAISREAGAPLSLRDIEEIAGKVAHIAKIAPSLATVHMEDIHRAGGVPAVLREAARRGGSVREGALTVTGETVGERIRDARTADPELIRPLENAYSPVGGLAVLFGNLAAEGAVVKTAGIQPSMRRFTGAAICFDSQDEAIAGIMGGKVKPGHFVVIRYEGPKGGPGMQEMLSPTSLIMGMGLGESVALVTDGRFSGATRGACVGHVSPEAAEGGVIGLVQDGDRITIDVEARALTVDVPDAELARRREGFRPKRRDPGSSWLRRYAHLVTNAANGAVLRSTDL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: HYPA_GEMAT
Sequence: MHELSIAQSIVDVAGAEARRLGASSVRVVYLAIGRLSGIEPGALLFSYELVAADTPLAGSRLVIEDIPIAIHCAPCAAIHELPGVNRFRCPVCDTPSGDIRRGRELDITGLEIDDGASTDFDSIDHDTSALGASQAPEIPA
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: RS12_SHESR
Sequence: MATVNQLVRKPRAPKVDKTNVPALNACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCAGVTSRRQSRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS18A_YEAST
Sequence: MSLVVQEQGSFQHILRLLNTNVDGNIKIVYALTTIKGVGRRYSNLVCKKADVDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQNDITDGKDYHTLANNVESKLRDDLERLKKIRAHRGIRHFWGLRVRGQHTKTTGRRRA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S18-A, Small ribosomal subunit protein uS13-A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHBA_ANETH
Sequence: MKNKALFLDRDGVINVEKNYVHKIEDFEFMDGIFETLRYFQEKGYLLIIITNQAGIGRGYYTEEQFHILNDWMLSEFEKEGIYITKVYYCPYHPEHGIGKYKRDSFDRKPNPGMILKSQKEFNIDLSKSILVGDKESDIQAGKRAGVNVNIIFSNNKNGDELDCCKKINSLSELVSLIL
What is the function of this protein?
Converts the D-glycero-alpha-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
What are the official names of this protein?
D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the GmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSIB_BACSU
Sequence: MADNNKMSREEAGRKGGETTSKNHDKEFYQEIGQKGGEATSKNHDKEFYQEIGEKGGEATSKNHDKEFYQEIGEKGGEATSENHDKEFYQEIGRKGGEATSKNHDKEFYQEIGSKGGNARNND
What is the function of this protein?
Involved in an adaptive response to nutrient deprivation other than sporulation.
What are the official names of this protein?
Glucose starvation-inducible protein B, General stress protein B.
Protein: PHYIP_BOVIN
Sequence: MELLSTPHSIEVSNITCDSFRISWTMENSDLERVTHYFIDLNKKENKNSNKFKHRDVPTKLVAKAVPLPMTVRGHWFLSPRTEYSVAVQTAVKQSDGEYLVSGWSETVEFCTGDYAKEHLAQLQEKAEQIAGRMLRFSVFYRNHHKEYFQHARTHCGNMLQPYLKDNSGSHGSPTSGMLHGVFFSCNTEFNTGQPPQDSPYGRWRFQIPAQRLFNPSTNLYFADFYCMYTAYHYAILVLAPKGSLGDRFCRDRLPLLDIACNKFLTCSVEDGELVFRHAQDLILEIIYTEPVDLSLGTLGEISGHQLMSLSTADAKKDPSCKTCNISVGR
What is the function of this protein?
Its interaction with PHYH suggests a role in the development of the central system.
What are the official names of this protein?
Phytanoyl-CoA hydroxylase-interacting protein, Phytanoyl-CoA hydroxylase-associated protein 1, PAHX-AP1, PAHXAP1.
What is the protein family that this protein belongs to?
Belongs to the PHYHIP family.
Protein: OMPH_PASMU
Sequence: MKKTIVALAVAAVAATSANAATVYNQDGTKVDVNGSVRLLLKKEKDKRGDLMDNGSRVSFKASHDLGEGLSALAYAELRFSKDVKNKDGEVIKQPIGNNVHAKRLYAGFAYEGVGTLTFGNQLTIGDDVGVSDYTYFLGGINNLLSSGEKAINFKSAEFNGLTFGGAYVFSDDFDKNGLRDGRGFVVAGLYNRKIGDVGFAFEAGYSQKYVKQEVASVLPPPPGSVTVYKDEKEKAFMVGAELSYAGLALGVDYAQSKVTNVDGKKRALEVGLNYDINDKAKVYTDFIWAKEGPKGATTRDRSIILGAGYKLHKQVETFVEGGWGREKDANGVTTKDNVVGVGLRVHF
What is the function of this protein?
Structural rigidity of the outer membrane of elementary bodies and porin forming, permitting diffusion of solutes through the intracellular reticulate body membrane.
What are the official names of this protein?
Major outer membrane protein, MOMP, Outer membrane protein H.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: GATD_HALWD
Sequence: MSPHPGDRVRVERADVTNEGILMPSSTSDHLVIKLDGGYNVGIDRADASIDLVTSDAYDIGGTQTDIGSSAGAGADTEADKTESDITSKSAASAVAFDESLPTVSLISTGGTIASTVDYRTGAVTAQFDAEDVLRAVPDLAGRANYRGRVVRNILSENMTPAVWQDLAAAVADEIRAGADGVVVMHGTDTMQYSASALSYMLDTPVPVVFTGSQRSADRPSSDNVMNAVCAVEAATADISGVFVCMHASTADDTCALHRGTRVRKNHTSRRDAFKTVGATPIGKIEYDTETVSFHRDHAARESTELNLTSELNEDVMLLTFTPGMNIDRQTAFLTDSTPDGLIIAGTGLGHVHTEFIPTVAELVADGVVVAMTSQCIEGRVCDRVYDTGRDLLEAGVVEAGDTLPGTAKVKLMWALANHPDPTNAMRKSLAGELQHRSVPWE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit D, Glu-ADT subunit D.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family. GatD subfamily.