PharMolix/UniProtQA huggingface dataset:
Protein: TIM8_CRYNJ
Sequence: MSAPTSIPALDEASKKELESFLEQEQAKAKLQASIHELTNTCWNTCITGGISSKFSKSEAQCLENCVDRFLDSSLYIVRQIEAQKQQI
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM8.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: GPDA_ACIF5
Sequence: MRWAVLGGGHWGTALAVYLLRQRHMVQLWGRRAERLPCQPGRTDLFPVFPECARPEGLHCTVDLAAAVQGGEGIVLAVPSHALRGLLTHLLPCLPSTALFVLASKGLEVPSALRLDQVLREILPEAPLVVLSGPSFAHDLMLGKPLAMTAASTDPTYAQRVAEAFGSAQMRVYTSDDVAGVCLGGAIKNVLAIAAGISDGLGNGDSARAALITRGMAELHRLGTALGGRTETFMGLAGAGDLILTSCSDLSRNRRVGLGLGSGLSLEAVLRGIGEEAEGVRTAQALFQLAQSLGVDMPITEQVYRVLFEGAAPRAASDELMRRALRSELHVSDDGTPGGAARTE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_ECOL6
Sequence: MELTTRTLPSRKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: Y399_RICBR
Sequence: MINYFFIFLVPSLGMVAGLSVAATVTVFLLISLLQNIAAWIPNRHCEEQSDVAISLNILRLLRQLFCNFLAMTIKTELLFAGWCLISCLFAIKPINSLINFVQVFTILFLGFVVSNFKPFQNRPKLKKALIFGTLTGILLFFVEYFSYGFLTRIFKANFNLYMLDRGCALLSITAWVVIAILIYDKKYCPALILYILVLYLLSISDSLASFLGFSLGGIVFILARFIKPIFSKLIIFGLITGSLLFPIIAGQINPKGLSDKYLTTHPSAAHRLFIWHFVANKIAEKPLMINGFNSSKYTQVKDSEMIDYKGEKWHPLPLHPHNNILQITLELGLIGLALFLSLVYKYLKQIGNIGNDNFRASSYACFINYYIIGMISYNVWQIWWIASSIWVLILMKLLVKPDIVIDK
What are the official names of this protein?
Putative polysaccharide polymerase RBE_0399.
What is the protein family that this protein belongs to?
Belongs to the O-antigen polymerase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL18_DEHMB
Sequence: MAKVNAREARIVRHERLRKKVSGTEARPRLCVFRSIENIYTQVINDNCGSTLVQASTKDAELKAELDGKTKTEQAVVIGNLIAKRSLEAGISEVVFDRGGYKYHGRVKALAEAARSGGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL15_AQUAE
Sequence: MVELHDLQPHWGATKEKKRVGRGIGSGHGKTAGRGHKGQKSRSGDRKMPPYFEGGQTPLYMRIPKRGFKNPTRKEYTPVNVGVIDKLFEDGMEITPEVLASKGLCDEKDRVKILGDGELTKKFVIKAHAFSKSAKEKIEKAGGKWEIIS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: YPB3_ECOLX
Sequence: MHEPPVQPDRCALSGNYRLESNPVRHDLSPLAAATGNRISRARYVGGATEFLKWWPNYGYTRRTVFGICALLKPVTFGKRVGSS
What are the official names of this protein?
Uncharacterized 9.4 kDa protein.
Protein: MUTL_XYLFM
Sequence: MPIRQLPEILINQIAAGEVVERPASVVKELVENAIDAGATRVDIELEAAGVRLIRIRDNGHGMAAQELPLAVLRHATSKIASLDDLEAVATLGFRGEALPSIASVSRFTLMSRRATDEHGAVLQIEGGTLGEVIPHAHAPGTTVEVRELFYNVPARRKFLRAERTELGHIEEWARSLALAHPDLELRLSHNGKLSRRYKPGDWYSDARLIEILGEDFAHQALRVDHSGAGLRLHGCIVQPHYSRLNADQQYLYVNGRPVRDRSVAHAVKQAYSDVLYQGRHPAYVLFLELDPARVDVNVHPAKHEVRFRDARLIHDFVYRTVQGTLAQTRAGTPPLAVGVGDVEGEGEGARPPGRHAVSFSGRRGGASHVLGSYSTSTAPLMQGVPSVSVADAPAAYAALYAAPPTQVMDAVPQMQTGLPLAAGAGDVPPLGYAIAQLHGIYILAECADGLIVVDMHAAHERIGYERLKRAHDGIGLRTQPLLVPMTLMVAEREADVAECEAETLASLGFEVTRSGPGSLQVRSIPALLSQAEPEMLLRDVLSDLSEHGHTRRVAEARDTLLATMACHGAVRAHRRLSISEMNALLRDMEATERSGQCNHGRPTWARFSLAEIDRWFLRGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PUL2_KLULA
Sequence: MLADILIPLIKKNWMAFVYFTPVLFVVLYLLKEWRAAYGFNNLGQTVAAPFGYERKTLPYNKENCARTKFLDGKSLSIKNRDQCGDLYLQRSGTYKEIVLTTPKQLMEYYKSNSKNHSKLDSFGAGAFLVALLGECLGFQNGSEWLSMRKVFDSFFTHKAAVENFPVMIDYISEWIKDLDTEQISDIDPLQLVSDLPFTCIAKYLYGSELCSKQFLQALKDLIPMHTELMHYSFLTVAGRFKIFQYFPSKKMKQVSQFQRQFIDLSLKQVELSRQSGQETVVEKLYRHVESGKFTFNNWIQTIDEILFANIEVTSTVMAWALVEMGSNIEEQNRLRCEILKVKEQSSKDDFNKETDPMQRYMKLTDTYLQYCVWETLRMHPLLWFSFPEISSETLFIDGIRISPNTPIVVDQYQINYNSPIWNPSDKPKDFGKKFAPSRFENITLRDALYSQVTFGAGSRKCLGRNFAELLIKSELAYILSKYKVTLTEKVEFSKDTFVVQPKTKIQLTAL
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the PUL gene cluster that mediates the formation of pulcherrimin, a red iron-containing pigment composed of two cyclized and modified leucine molecules that acts as a siderophore, a chelator that binds iron outside the cell for subsequent uptake (PubMed:30297402).  Two leucine molecules are cyclized via a cyclodipeptide synthase, and the resulting diketopiperazine is oxidized by a cytochrome P450 monooxygenase to generate pulcherriminic acid (PA), which can then spontaneously bind iron to form pulcherrimin (PubMed:30297402).  The probable cyclodipeptide synthase PUL1 and the cytochrome P450 monooxygenase PUL2 encode the enzymes responsible for the two-step pulcherrimin biosynthesis pathway (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase PUL2, Pulcherrimin biosynthesis cluster protein 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL6_HELAH
Sequence: MSRIGKRIIEIPSSVQASVEGSKLLFKNNKEKHELETHNRVKITLENNQLSFQPIGEDVQSRAYWGTYGALANNIVIGLSTGFSKTLEVNGVGYKVALGNKTLDLSLGFSHPVKYPIPAGIEMVVEKNTITIKGSDKQKVGQVAAEIRSFRPPEPYKGKGVKYSDEVIIRKAGKTAKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: LTO1_SCHPO
Sequence: MDWEEVTKLEENEYKRGYDEGILKGIEQGYEEAFLFGLEHAYNKYLLAGEIYGRVCFWLKEENSQHPKIKKAHRHLEQLKSLLESLPTNNELEETDAGFDSYWNKITAKAKVVSSLLGTKILPAEKIDANDGFE
What is the function of this protein?
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery.  May be required for biogenesis of the large ribosomal subunit and initiation of translation.
What are the official names of this protein?
LTO1 family protein C191.08.
What is the protein family that this protein belongs to?
Belongs to the LTO1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FARS_MAIZE
Sequence: MDATAFHPSLWGDFFVKYKPPTAPKRGHMTERAELLKEEVRKTLKAAANQITNALDLIITLQRLGLDHHYENEISELLRFVYSSSDYDDKDLYVVSLRFYLLRKHGHCVSSDVFTSFKDEEGNFVVDDTKCLLSLYNAAYVRTHGEKVLDEAITFTRRQLEASLLDPLEPALADEVHLTLQTPLFRRLRILEAINYIPIYGKEAGRNEAILELAKLNFNLAQLIYCEELKEVTLWWKQLNVETNLSFIRDRIVECHFWMTGACCEPQYSLSRVIATKMTALITVLDDMMDTYSTTEEAMLLAEAIYRWEENAAELLPRYMKDFYLYLLKTIDSCGDELGPNRSFRTFYLKEMLKVLVRGSSQEIKWRNENYVPKTISEHLEHSGPTVGAFQVACSSFVGMGDSITKESFEWLLTYPELAKSLMNISRLLNDTASTKREQNAGQHVSTVQCYMLKHGTTMDEACEKIKELTEDSWKDMMELYLTPTEHPKLIAQTIVDFARTADYMYKETDGFTFSHTIKDMIAKLFVDPISLF
What is the function of this protein?
Sesquiterpene cyclase catalyzing mainly the production of beta-farnesene and alpha-bergamotene in equal amounts from farnesyl diphosphate (PubMed:19646721, PubMed:16418295, PubMed:21607717).  Mediates also the biosynthesis of minor sesquiterpene hydrocarbons including alpha-muurolene, beta-bisabolene, zingiberene, sesquiphellandrene, sesquisabinene A, germacrene D, delta-cadinene, alpha-copaene and (E)-beta-caryophyllene (PubMed:16418295, PubMed:19646721).  Involved in indirect defense by producing volatile signals attracting natural enemies of herbivores (PubMed:19646721, PubMed:16418295, PubMed:21607717).
What are the official names of this protein?
(E)-beta-farnesene synthase, (+)-germacrene D synthase, (E)-alpha-bergamotene synthase, Alpha-copaene synthase, Alpha-muurolene synthase, Beta-bisabolene synthase, Beta-caryophyllene synthase, Delta-cadinene synthase, Sesquiphellandrene synthase, Sesquisabinene A synthase, Terpene synthase 10, Zingiberene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2213_SACS2
Sequence: MIKAYFGAETFTLNKDFAYILVIGTTDVSLIPGLTIAGATPELTHFTPAADAEYVILGKCKSINTIPVSPTGIPTPALLTRASLSFTKSLKIVVNAGSRITPKIPYIDLQGEPGKDIRKQALSIEKVNIIIENGIKLGEELSNEYELIMIGESIPAGTTTAMATLLALGYDAMDKVSSASPDNPKELKRKVVEEALRNLPTDPLQRLAKVSDPVLLGVAGISLGFRGKILLAGGTQMTAAAAIVNEFDKSKLKDIIIGTTKWIVEDKSADMLSLAKQVGVKVLASMLDLSISIHEGIRTYEKGYVKEGVGAGGSTIMAFIRGVSNSTLVRKIDELYSELVGSNNLNT
What are the official names of this protein?
UPF0284 protein SSO2213.
What is the protein family that this protein belongs to?
Belongs to the UPF0284 family.
Protein: FCP_ISOGA
Sequence: MMTLASLPSTAIAGLASAAPKVQPRMAANDEFAYGLPGGANILGEFDPAGFLKGKDKLEVYRLREAETTHGRVAMLASLGFVVQEKFHPLFSGDNGPAIEQIPQLPYWLWIVMTIGIGRAELFRIQKGWAKVNPETGKADSALREGYEPGDLGFDPLGLAPSDPDEFRLMQEKELSHGRLAMIAAAGFLAQEAVSGDTWGTYWGDATF
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.  Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
What are the official names of this protein?
Fucoxanthin-chlorophyll a-c binding protein, chloroplastic, FCP.
What is the protein family that this protein belongs to?
Belongs to the fucoxanthin chlorophyll protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=FCPs are probably transported across the endoplasmic reticulum membranes that surround the plastid via a signal peptide, followed by translocation across the thylakoid membrane via a transit peptide.
Protein: CLCA2_HUMAN
Sequence: MTQRSIAGPICNLKFVTLLVALSSELPFLGAGVQLQDNGYNGLLIAINPQVPENQNLISNIKEMITEASFYLFNATKRRVFFRNIKILIPATWKANNNSKIKQESYEKANVIVTDWYGAHGDDPYTLQYRGCGKEGKYIHFTPNFLLNDNLTAGYGSRGRVFVHEWAHLRWGVFDEYNNDKPFYINGQNQIKVTRCSSDITGIFVCEKGPCPQENCIISKLFKEGCTFIYNSTQNATASIMFMQSLSSVVEFCNASTHNQEAPNLQNQMCSLRSAWDVITDSADFHHSFPMNGTELPPPPTFSLVQAGDKVVCLVLDVSSKMAEADRLLQLQQAAEFYLMQIVEIHTFVGIASFDSKGEIRAQLHQINSNDDRKLLVSYLPTTVSAKTDISICSGLKKGFEVVEKLNGKAYGSVMILVTSGDDKLLGNCLPTVLSSGSTIHSIALGSSAAPNLEELSRLTGGLKFFVPDISNSNSMIDAFSRISSGTGDIFQQHIQLESTGENVKPHHQLKNTVTVDNTVGNDTMFLVTWQASGPPEIILFDPDGRKYYTNNFITNLTFRTASLWIPGTAKPGHWTYTLNNTHHSLQALKVTVTSRASNSAVPPATVEAFVERDSLHFPHPVMIYANVKQGFYPILNATVTATVEPETGDPVTLRLLDDGAGADVIKNDGIYSRYFFSFAANGRYSLKVHVNHSPSISTPAHSIPGSHAMYVPGYTANGNIQMNAPRKSVGRNEEERKWGFSRVSSGGSFSVLGVPAGPHPDVFPPCKIIDLEAVKVEEELTLSWTAPGEDFDQGQATSYEIRMSKSLQNIQDDFNNAILVNTSKRNPQQAGIREIFTFSPQISTNGPEHQPNGETHESHRIYVAIRAMDRNSLQSAVSNIAQAPLFIPPNSDPVPARDYLILKGVLTAMGLIGIICLIIVVTHHTLSRKKRADKKENGTKLL
What is the function of this protein?
Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner, and cell adhesion.  Involved in basal cell adhesion and/or stratification of squamous epithelia.  May act as a tumor suppressor in breast and colorectal cancer.  Plays a key role for cell adhesion in the beginning stages of lung metastasis via the binding to ITGB4.
What are the official names of this protein?
Calcium-activated chloride channel regulator 2, Calcium-activated chloride channel family member 2, hCLCA2, Calcium-activated chloride channel protein 3, CaCC-3, hCaCC-3.
What is the protein family that this protein belongs to?
Belongs to the CLCR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Basal cell membrane; Single-pass type I membrane protein. Cell junction. SUBCELLULAR LOCATION: [Calcium-activated chloride channel regulator 2, 109 kDa form]: Secreted. Note=Remains associated to the 35 kDa form until an unidentified event triggers the release.
Protein: Y0811_DICDI
Sequence: MVNNKRKEIDNINEHHEKDYNHDNGNQQEKKKEEQPQQQQKKQCILSFKDVEPVEIYFWKVFRNIFIFKHIFSNFKSKQYGYYDLIGCDEIFFLNGRTNSMEIIIDNIKSNNNHQIIRNESNIIDIIHTFKKNDEKTRSFYNLLFSRYSSGSTSPIQLSSTIRFDENIDKWIQRMIKNVNCTALDQFIKFFKIDSEAIKKVMEIHIKPSFFGYTTYGKLKIYNYLKSINSLPTSHKLLPFINTDLEIFLSFDNKFKKFIKSYKRLIESTNLQEQQEQQEKQGKLKIHPNNKKYYEKLNQKILELNEIQTSQFTNDQLNSTIKNLLNHTTPTSTSITTTTTTTTTNLTIISTESNYNNNNNHNHNNINSNNKINLKDIIKKYYESIYLFFYFTVKPENKGVFRKGLFYYLKFKKESVDKMYERVVNKWNGSSFDHKLFFQSILKDINIEKNEKFELILNVLDNKYVKTFREYDHYIFFKAVFSSNDIELIDYFLKKIKQLQLNQIPEITKYPSIGKLICDYCHLIDKKEILDFYFQNYRDECLLFNDQNENCKYIQLELIEHYEYLTGSIGNRCKLDFIYWYKNLNFLDRLNRAIMKPLVYSIDFGGSSSDFKWLIDSNINNNKENSIINFLSNAQFKQPLDLEILGSSFSPYAAKLLTLIKFLFNNISKESIETKLKVINLKTDNKNFEEKYSKIEFTTTLTTATNLLSPKKSEDVGCLTIGKTESFNFTISITTLLVCLYKLDRVDDIIYLFDKLPEVFLKSYYSSIFTKEYCIYSISSSYYLELFINYFIANLNDTTNYLYHCLCIASEKGYTQIFKNIISSDQNSKYLLKIQTESNQSSLFDSKLLNDIVDKSISSLNFELSNLLIDFIDFSANGQNTLKMKILKLK
What are the official names of this protein?
UPF0746 protein DDB_G0280811.
What is the protein family that this protein belongs to?
Belongs to the UPF0746 family.
Protein: SAHH_PSESM
Sequence: MSAVITPAEFNDYKVADISLAAWGRRETIIAESEMPALMGLRRKYAAEQPLKGAKILGCIHMTIQTAVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIAVYAWKGETEEEYEWCIEQTILKDGQPWDANMILDDGGDLTEIIHKKYPAMLDKIHGVTEETTTGVHRLLDMLAKGELKIPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSAQSLRQEGMIVKVTEVDPICAMQACMDGFELVSPFIDGENDGTEASIDKALLGKIDLIVTTTGNVNVCDSNMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGAGAFDAQNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIFLFDQKYADLAPAKKAERLTVEVLPKKLDEEVALEMVRGFGGVVTKLTKTQADYIGVTVEGPFKPDAYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL4_ORYSJ
Sequence: MSVSAAVAAASTSRTLVLARHRSPPASRVAATSRGRPFSSGPHPLAVSPATRAPAMATDGAAAAAAAGSKKKKEVLIFDAEEDLAVSLAKYTAELSAKLAAERGAFTVVLSGGSLIKNIRKLAEPPYLDSVDWSKWHVFWVDERVVPKDHEDSNYKLALDGFLSKVPIPTGQVYAINDALSAEGAADDYETCLKQLVKNGVIAMSQSTGFPRFDVMLLGMGPDGHIASLFPGHPLVNENKKWVTYIKDSPKPPPERITFTFPVINSSAYVAMVVTGAGKAGAVQKALSDKQTSSDLLPVEMAVLQDGEFTWFTDKPAVSMLQNK
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
Probable 6-phosphogluconolactonase 4, chloroplastic, 6PGL 4.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CTU2_KLULA
Sequence: MVICKRCKLLDATLVSRKEPFCDECFVKFISLKQRKQMMSDDYFQDIFKISYPDKKRGQAEADKQNQDSNVLVPLSLGSSSLAVLDILNDTLLEQKQTHRGKTGFHVEVITICGQAEFEEVRGKIELLKSKYKENSDKILFHIVDRNQFFAVPFDLQEITLYIDNFNTLVRSSNNPSTTVEKVLASAPNKTAKEDLLNIIYTHLIKKFALQRNFKAILWGHSMTKLADEVISLTVKGRGAEIAGYLDDSSLDSKYNTAFRNFHPGRDVLLSEIDAYCHIKGLSQFSHNYVVQDTLFYDKFVDKPTKNVKLIKNMTMNELARQYFDNIEGDYSNVISTVVRTGAKLSNPDNELNQIMHCSICNAIIYKNPVNWLDGITVSKPFVIHNEEELTNYNAWEAANPDKAEKLNKMSDTPAKNVGVCYGCITTLTGMKDRKLEWIRRDDKAELTAVLQEYEIPSDDSEQ
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_SHESM
Sequence: MKFKQDFFTQLPEFYSQVYPQGISNPHWLAWSEDAAKLIDLQQPTDALLQGLSGNAAVEGASYYAQVYSGHQFGGYTPRLGDGRSIILGEALGPQGAWDVALKGGGPTPYSRHGDGRAVMRSAVREFLVSEALHHLGVPTTRALAVIGSDMPVWRESQETAAITVRLARSHIRFGHFEFFCHSERGQADKLTQLLNFTLKQHYPNLSCDLAGYKAWFLQVVQDTAKLIAHWQAIGFAHGVMNTDNMSILGDSFDFGPFAFLDTFQEDFICNHSDPEGRYAFGQQPGIGLWNLQRLAQALTPVIPSDDLIAALNQYQHALVQHYLMLMRVKLGLTERADSTAEQDQQDLELIGRFTVLMEKNQLDYSNTWRRFGQLDPSSAHSSLRDDFIDLNEFDAWYQAYQARLGKVTDIEAWQQARNSVNPKYILRNYLAQEAIIAVEEGNLAPLERLHQVLRQPFAEQVEHEDLAKRPPDWGQGLIMSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: EAR_EBVG
Sequence: MAYSTREILLALCIRDSRVHGNGTLHPVLELAARETPLRLSPEDTVVLRYHVLLEEIIERNSETFTETWNRFITHTEHVDLDFNSVFVEIFHRGDPSLGRALAWMAWCMHACRTLCCNQSTPYYVVDLSVRGMLEASEGLDGWIHQQGGWSTLIEDNIPGSRRFSWTLFLAGLTLSLLVICSYLFISRGRH
What is the function of this protein?
Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus.  Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell (By similarity).
What are the official names of this protein?
Apoptosis regulator BHRF1, Early antigen protein R, EA-R, Nuclear antigen.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Host mitochondrion. Note=also observed in the perinuclear region of the cell.
Protein: ERIP6_HUMAN
Sequence: MAHLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTETPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEESWLQDLSDKVQSRKKASKEKAEPECLASKLREKWVINPEESKLNILYELEFKEDFITLFEPSLRTLPSIGPPSILAYKEESSNLGINFKDEEEETSPKCEFCGSDLRAFFSNVDVSSEPKGHASCCIAFQNLIDYIYEEQIKTKPPKAELIAIDPHAAHGSEVDRLKAKEKALQRKQEQRMARHFAIISREQTHFSEDDSKRLKTISYQLSVDIPEKQIIDDIVFDFQLRNSNMSIICCDSRIACGKVVRNELLEKHYKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVNGFTCIVQEDMPTNPAILAVLDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNSITSSPFVSFKPVFLALNRYIGVRILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASLIKIRRLFHKLEGCVNFPSSQVWEKLKQPSYLSSLSLKLIALCHSSGIKQDIMKTIRNIINEEI
What are the official names of this protein?
Glutamate-rich protein 6, Protein FAM194A.
What is the protein family that this protein belongs to?
Belongs to the ERICH6 family.
Protein: ENGB_CLOBB
Sequence: MRIKQSEFIISAVKPHQYPIDHRNEVAFVGRSNVGKSSLINSLTNRKKLAKVSGTPGKTRLINFFLINNDFYLVDLPGYGYAKVSKSEKDTWGKTIETYLSHREELKRIVCLVDSRHKPTGDDIMMYEWAKHFGYDVVVVATKSDKLKNAEFKKSEKLIRETLNLTKDDKLYFYSSLNKKGTEELIDKLFLEFATDID
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ACDH1_BURL3
Sequence: MKSKAKVAIIGPGNIGTDLMIKVMRHGTHIEMGAMIGVDPKSDGLARAQRMGVAISSDGIDGLLALDVFKEIDIVFDATSAGAHKRHNDVLQAHGVQVIDLTPAAIGPYVIPAINLESENAPNMNMVTCGGQATIPMVAAISRVTKVHYAEIVASISSKSAGPGTRANIDEFTETTRKAIEQLGGASRGKAIIILNPAEPPLIMRDTVFALSDPADQGKIEDSIAQMVASVQAYVPGYRLKQKVQFDVITADKPLNVPGVGLKHGLKTSVFLEVEGAAHYLPSYAGNLDIMTSAALACGDMMARRRMAAGIARGHKEAV
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: MDTJ_SALPB
Sequence: MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKEATRATI
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MOSP_RUMA7
Sequence: MKTQIINGVSLPNIPWQDKPADCKDVIWRYDANPIIPRDQLPTSNSIFNSAVVPYESEKGKFAGVFRVDDKCRNMELHAGFSKDGIHWDINPDRIVFEQAEKSTEEVNQWGYGYDPRVCFIEDRFWVTWCNAYGWKPTIGVAYTFDFKTFYQCENAFLPFNRNGVLFPRKINGKYVMFSRPSDSGHTPFGDMFISQSPDMKYWGEHRHVMGPLRAWESKKIGAGPIPIETSEGWLCFYHGVLESCNGFVYSFSACILDKDEPWKVKYRCAEYLLSPQKIYECVGDVQNVTFPCATLVDADTGRIAIYYGCADTCVSMAFTTVDDVVDYVKSHSSV
What is the function of this protein?
Catalyzes the phosphorolysis of beta-1,4-mannooligosaccharides to mannose 1-phosphate (Man1P) and shorter mannooligosaccharides.  Can also catalyze the phosphorolysis of 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc), but shows higher activity toward longer mannooligosaccharides.  Involved in a mannan catabolic pathway which feeds into glycolysis.
What are the official names of this protein?
Beta-1,4-mannooligosaccharide phosphorylase, RaMP2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 130 family.
Protein: LEUC2_METKA
Sequence: MPSVAERILSEKVGEPVEAGETVYVEPDVIMLHDGSGATALRTLRELGVERVESPEKVVLIFDHSVPPSSVEAANRQNELLEFARRHRIEHVHVDEGVCHQVLVEEGYAGPGRVVFGGDSHTPTSGAASALAFGFGGTDMAFALLYGELWIRVPRTVRVHVEGELEEPATAKDLALTVVGELGAGYADYAVLEYTGLPERMSLGDRMCLCNLATEAGAKSAYVPPKEGPEELRPGDADEVIELDASEVEPVVSVPHRVDDVRPVGDVQGVEVTRVFVGSCTNGRYRDVRVFTEILEELDGPHPDVRIVVVPASRRVLERMTEAGLTLKLIRMGVMIAPPGCGPCLGEHLGVLGDDDVCVSTANRNFPGRMGSRRAEIYLASPVTAAVAAAEGELVDPQDVLG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit 2, Alpha-IPM isomerase 2, IPMI 2, Isopropylmalate isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.