PharMolix/UniProtQA huggingface dataset:
Protein: ATPF_EXIS2
Sequence: MNLTYRAAEGVAESNHLLLANMIVTIVVFLLLLILLKKFAWGPLVNMMKAREEHVASEINSAEKSRKDAEVYVEQQQAELNKARTEARDLLEASRRQAEAEQARAMEQARVETELSKEEARRAIERERAEAQAALKNDVALQAIAAARHVMKTQLATDEAAQRALVDQFLADTKGTN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SPH31_ARATH
Sequence: MKILSVFLFVFSIYIFGHVSGTGIRIVNELKSHKNLWMRCYSKNDVIGPKIIPVGYDYVNSFRANIWGTTRFMCTLKQRPNYRHYQNFTAFKQYTAYDNGADWDWRAREDGIYLKKEGGLKKSVDMNKVYDWIN
What are the official names of this protein?
S-protein homolog 31.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTL_CLOTE
Sequence: MKRINILDECTFNKIAAGEVVERPFSVVKELVENSIDAEAKNITVEVKNGGQDLIKVSDDGAGIYADDIQKAFLTHATSKILNIDDIFSLNTMGFRGEALPSIASISKILLKSKPLSETSGKEIYMEGGNFISFNDVGMNTGTTIKVTDLFYNVPARLKFLKSSSRESSLISDIIQRLSLANPDIAFKLINNGKTVLNTYGSGNLEDAIRVIYGKKTLENISYFESHSDIISVYGYIGNAELSRGSRNNQSIFVNKRYIKSGLITAAVENAFKSFLTINKFPFFVIFIDIFPEYIDVNVHPTKTEIKFKEDKIVFSFVFKTVHESIKKSLYKEFNEQIKEDVKEDNKEIIKENPSLFQNVEKVQIPIDLKSASMDIERKSLVNSVLCNENNIVKDNINKNIYIDTKENLSENKLKNILKENTEDMVSKLPDMKIIGQFDNTYILAESVKNLYIIDQHAAHEKILFETYRDKIKKDEVKSQLLLQPIVLELDSEDFSYYVDNKELFYKTGFNIEVFGENTINIREVPFIMGKPDINNLFMDIINNIKAMGSGETIEVKYDSIAMLACKSAVKAHDKLSKEEMEALINDLRFAKDPFNCPHGRPTIIKITSLELEKKFKRIQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ATP6_MYCGE
Sequence: MSPREIVLKETNQIDFISNQSIFDISPISGWKPFAPTDQILGIFIVFVLLLTFFIFYKLKLKKADSLKNNSYFLLLFQMLFVWVQDTTADLLGEENKKFAPYFLMLLLYIVSSNLVSLLGGISPPTSSLTFTFSLGLATFIGIVVMGIRYQRWNFFKEFAFGITVKGKKYSTFIPNPFSILSGFAPLFSISLRLWGNILAGTVILALFYNFWIFIFSSINNQPLALSLGTVFAGLITPVLHIYFDVIAGVLQGYVFVMLTYNYWAKMRNQGLENNNASELHFKGIKVIQENI
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURB_RHOPB
Sequence: MALFPDLVPELKAAMPQLRGRLLGNEPLAPLTWFRVGGPAQVLFTPADADDLGYFLAALPRDIDVTVVGVGSNLIVRDGGLPGVVIRLGGRGFGETGTDGDVVSAGSAALDKRVAEAAAAAGLGGLEFYHGIPGTIGGALRMNAGANGRETKDVLIDASAIARDGTLHRLSNAEMGFSYRHSGADPALIFTSARFRGEPMDRAAIRARMDEVQRHRETAQPVREKTGGSTFKNPPGHSAWKLIDAAGCRGLRVGGAQVSEMHCNFLINTGSATAQDIETLGDTVRARVKEHCGIELQWEIKRIGRALD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBL_METTM
Sequence: MKRFSDKRTQIKTVMATGTFDIIHPGHGFFLEEAKKLGGENARLVVVLARDSTVRARKRTPIIGEKQRLEVVMMLKPVDEAYLGSETDMFEIVHRLKPDIIAIGPDQKFDIDELRDELRRRGLECEVKRVGKYRRSELDSTCKIIKKIRKMEFDEDALKNC
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: ILVE_MYCLE
Sequence: MTSGFLEFTVSLSAHPVTDAERESILAEPGFGKYHTDHMVSIDYIDGRGWHDARVIPYGPIQLDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPDANAARLRSSARRIAIPELPDELFIDSLCQLIAVDNAWVPRVGGEEALYLRPFIFATEPGLGVRPAKQYRYLLIASPVGAYFKGGINPVTVWVSMEYVRASPGGTGAAKFGGNYAASLLAQTEAAANGCDQVVWLDAVERRFVEEMGGMNIFFVLGSGGSARLVTPELSGSLLPGVTRASLLQLAIDAGFSVEERKIDIDEWQKKAAAGEITEVFACGTAAFITPVSRVKYGDTEFTIAGGAPGEVTMALRDTLTGIQRGTFADTHGWMARLG
What is the function of this protein?
Acts on leucine, isoleucine and valine.
What are the official names of this protein?
Probable branched-chain-amino-acid aminotransferase, BCAT.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: CBSX1_ARATH
Sequence: MDAVLYSVPLSFTPLRASSSPSSPYLLLPRFLSVQPCHKFTFSRSFPSKSRIPSASSAAGSTLMTNSSSPRSGVYTVGEFMTKKEDLHVVKPTTTVDEALELLVENRITGFPVIDEDWKLVGLVSDYDLLALDSISGSGRTENSMFPEVDSTWKTFNAVQKLLSKTNGKLVGDLMTPAPLVVEEKTNLEDAAKILLETKYRRLPVVDSDGKLVGIITRGNVVRAALQIKRSGDRNA
What are the official names of this protein?
CBS domain-containing protein CBSX1, chloroplastic, CBS domain-containing protein 2, AtCDCP2, Protein LOSS OF THE TIMING OF ET AND JA BIOSYNTHESIS 2, AtLEJ2.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CPGS_PYRFU
Sequence: MKLALIDGEHYPDVNRWAIEKIKPCCAVFVGGTEKIGSIRDIEKALNIKVYHSPNIFEALSKAISENNITEVIDLSDEPVLTPNLRFRIASYLLKLGITYKGADFEFRAKEWKKIDIPSISIIGTGKRVGKTAIGGFVGRTLKELYKVVIVTMGRGGPEKPEVIRGDLMEITPEFLLKVSEEGKHAASDHFEDALTAGVITVGCRRCGGGLAGFSFFDIIDEGIEIAKSLNPDIIVFEGSGPTFPNVLADGFITITSAIHGTEKIEQYFGPLRIGLADIVVVTMADSVSEEKLKRITQAIREINPEADIHLTRFVPRLIGEVDGKAIIATTNPQSAKKFSEELEKMGIEVVYYTGNLAKRNILKDELAKVNYDDTAIVELKAGAVDVVIRHAFSRGKRVVFLDNEPKNIDGKDLKEAVINLARRIVNDKGN
What is the function of this protein?
Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
What are the official names of this protein?
Cyclic 2,3-diphosphoglycerate synthetase, cDPGS.
What is the protein family that this protein belongs to?
Belongs to the cyclic 2,3-diphosphoglycerate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPIIA_MAGO7
Sequence: MKYSVGITALLATLAQGAAVMSKRDIPLDVKIQVVNNSEVKASITNSGSSSIKVVKTGSILDSADVEKSVIMAGENKVAFDGIRYQVATAGLPAEAFQIIEAGETIEVSFNVASTHDFAQGGDFDIAALGTFSVAESDSGDIFSAMAFESNHIKAHIDGTEAAKVRRSYLAKRTMVQSDCTGTRLTQTTNAINSCRSLAQRAASAAQSNSAKMNEYFKSTSSSAVNTVVTTFNRIASECNPSGGASRQYCTDQIGACSPGVIAYTVPSQSIMVNCPTFFTMPTTSNACRAQTQDNTILHEVTHLSQVKGTQDYNCYGYTCMRQLTSAQNLNHADTYTLFAQAIKVGC
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog MGG_10927, Deuterolysin MGG_10927.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNC_CERS4
Sequence: MKLSADLKAFEGRIGHQFREPERLLRAVTHSSLSSVTRSDNQRLEFLGDRVLGLVMAEALLAADRAASEGQLAPRFNALVRKETCAAVAREVALGDVLKLGRSEMMSGGRRKEALLGDALEAVIAAVYLDAGFEAARQLVLRLWGARIAQVERDARDAKTALQEWAQARGLPPPTYEAVDRSGPDHAPIFTVEVRLGNGETDRAAAGTKRVAEQAAARALLARMEARHD
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_SHEDO
Sequence: MTQLTQSSCWQALIADAAKLPHMRDLFAQNPQRFEQMSLNACGLFLDYSKNRADETTLKLLFSLAKEAKLTEKIAAMFNGDIINTTEQRAVLHTALRSKACQDIRVDGVNIVPEVQQTLDKMAQFVDSVQTGQCKGYTGKRITDIVSIGIGGSFLGPKIVSQALRPYWKAGLNCHFVANVDASSICEKLKLLNAETTLFVMSSKSFGTQETLTNTLSAKDWFLDQGATQADIAKHFVAVTSNVTKATEFGMDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRLLLDGAHQMDEHVKAAPLEQNMPVIMALLSVLYTNFHGAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGTQVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFIMPLQSHNPLGEHHAQLASNCFGQTQALMQGRTFEEAMAELSQSSLNEADKTLIAKHKVMLGNKPSNTLLMDKLTPQTLGSLIALYEHRTLVQGAIWQINSFDQWGVELGKQLGNDVLARIGAAHNATELDSSSNALINRFRQGKI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_GEOSE
Sequence: MKRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEGQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHERTYVIEVMGRHAGDIALWSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGVGSGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEALANKHTIDQRMYALSKELSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_CLOPE
Sequence: MDFILKMKDKSLKNIKLTREEGLRLFNSNLEELIKEANNIRKEIHGDGIDLCSIINGKSGRCGEDCAFCAQSKYHKTNISEYPLLDYEKIKKVAKENEDEGVHRFSIVTSGRGLYGEEFERVITYYSNLNKELKINLCASHGIINKESLIKLKKAGVKRYHHNLETSRNYYDKICKTHSYEERVKTIKNAKEAGLEVCSGGIIGLGETILDRIDLAITLRELEIKSIPINVLSAIKGTKLQNMIPLNEEEILRTIAVFRFINPEAKIRLAGGRYLLKNFGENAFKAGANATITGNLLTTCGNKIKDDKRLIENIGMRIF
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: KDPA_GEOKA
Sequence: MWHVFSQYTLIFLLLIVIAVPLGKYLYVAFFEKGKIDRFFSPIEAVIYRLSGIRSLEEMTWKSYCTALLIVNAALLGISYGLLRIQHYLPLNGAKVENMEPTLTFNTVVSFMTNTNLQHYSGESGLSILSQMLFVTMMMFTSAATGLTVATALIRALSKKGKTIGNFYQDFVRANVRVLLPLSVIVTILLVAFGVPQTFLARMAVSTLEGGTQTLALGPVASLESIKHLGTNGGGFFGANSSHPFENPHPFTNVIEMLSMWCIPAALPFTYGHAVKNRKQGWVLFATMFVLFVMMLGVVYNAEQSGNPLVGKSGFAADQGNMEGKEVRFGIPLSSLFTAITTAATTGSVNNMHDSLTPIGGLVPLALMMLNNVFGGDGVGFVNIMMYAMIAVFLSGLMVGRTPEFLGRKIEPKEMKLIVIALLLHPLIILAPSAIALMTHMGTEAISNPGFHGISQVVYEYTSSAANNGSGFEGLKDNTAFWNISTGVVMLLGRYVSIIAMLAVAGSLVGKQPVPETIGTFRTDTATFGVILFGTVFIIGALTFFPVLILGPVAEYLTIR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRCA_ACTP7
Sequence: MIKGVQITESSNSNLVNSFWLLDEEKNEARCIAAKGDVYKEDQVIAISELGQIAYREVPVNVAPTIKVEGGQHLNVNVLRRETLEDAVKNPEKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: RS10_CLOBL
Sequence: MAKQKIRIRLKAFDHSLLDQSALKIVETAKTTGAKVAGPVPLPTEKDIVTILRAPHKYKDAREQFEIRTHKRLIDIISPSPKTVDALMRLDLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RSMA_PSEPF
Sequence: MTEQYQHKARKRFGQNFLHDAGVIDRILRSINAKAGDRMLEIGPGQGALTAGILNSGAQLDVVELDKDLIPILNQQFAGKSNFNLHQGDALKFDFNSLNAAPNSLRVVGNLPYNISTPLIFHLLNNAGIIRDMHFMLQKEVVERLAAGPGGGDWGRLSIMVQYHCRVEHLFNVGPGAFNPPPKVDSAIVRLVPHAVLPHPAKDHRLLERVVREAFNQRRKTLRNTLKQLLSNAEIEAAGVDGSLRPEQLDLAAFVRLADKLAEQPAKAPEAD
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI17A_HUMAN
Sequence: MEEYAREPCPWRIVDDCGGAFTMGTIGGGIFQAIKGFRNSPVGVNHRLRGSLTAIKTRAPQLGGSFAVWGGLFSMIDCSMVQVRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAGILLTRFASAQFPNGPQFAEDPSQLPSTQLPSSPFGDYRQYQ
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ALLC_PSEA7
Sequence: MNADHAPFRHYLDLADARLGSQVVAVSDEWFAPASRMLQAGEPVWKEGVFDDSGKWMDGWETRRKRFEGHDQAVIRLGVSGVLKGVDIDTRFFTGNHPPAASLDGCFCAEGDPDDGTSWSEVLPSVELQGDRHHYHAIDDERPWTHLRLNIYPDGGIARLRVYGVPYRDWRSQTPGTALDLAAAINGGRALACSDQHFGPMVNLLKPGRALNMGDGWETGRRRTPGHDWAIIALGHPGSIEAAVVDTLHFKGNYPESCSIQAAFVEDGNEARIEAQSLFWRELLPAQKLEMHHEHRFERQLNALGPVSHVRLNIFPDGGVSRLRLFGRPQLP
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: RB11A_BOVIN
Sequence: MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDYTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKVQCCQNI
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  The small Rab GTPase RAB11A regulates endocytic recycling.  Acts as a major regulator of membrane delivery during cytokinesis.  Together with MYO5B and RAB8A participates in epithelial cell polarization.  Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.  Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells.  Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane.  Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane.  Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes (By similarity).  May also play a role in melanosome transport and release from melanocytes (By similarity).
What are the official names of this protein?
Ras-related protein Rab-11A, Rab-11.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Recycling endosome membrane; Lipid-anchor. Cleavage furrow. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle membrane. Note=Translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. Localizes to the cleavage furrow. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB8A in apical membrane initiation sites (AMIS) during the generation of apical surface and lumenogenesis.
Protein: OCE1_LEPPU
Sequence: MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKDAGKQLVAHAMGKIAEKV
What is the function of this protein?
Has antibacterial activity against Gram-negative bacterium E. coli ATCC 25922 (MIC=300 uM) but not against S. pneumoniae ATCC 700603, S. choleraesuis ATCC 14028 or Gram-positive bacterium S. aureus ATCC 29313.  Shows virtually no hemolytic activity and no cytotoxicity.
What are the official names of this protein?
Ocellatin-PT1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ocellatin subfamily.
Protein: SHE1_YEAS7
Sequence: MNDKLQEEHNEKDTTSQINGFTPPHMSIDFHSNNNSNIIETIGVSKRLGNSVLSELDSRASSKFEFLKDQSEQQYNGDKNNEPKSGSYNINEFFQAKHDSQFGQMESLDTHYTLLHTPKRKSQHAIPQDRSDSMKRSRPSRSIPYTTPVVNDITRRIRRLKLRNSLVNGNDIVARARSMQANSNINSIKNTPLSKPKPFMHKPNFLMPTTNSLNKINSAHRNTSSSSTASSIPRSKVHRSTSIRDLHAKTKPVERTPVAQGTNSQLKNSVSVFDRLYKQTTFSRSTSMNNLSSGTSAKSKEHTNVKTRLVKSKTSGSLSSNLKQSTATGTKSDRPIWR
What is the function of this protein?
May have a role related to the spindle integrity function of the DAM1 complex, which is essential for proper chromosome segregation.  Causes growth arrest when highly overexpressed (By similarity).
What are the official names of this protein?
Mitotic spindle-associated protein SHE1, Sensitive to high expression protein 1.
What is the protein family that this protein belongs to?
Belongs to the SHE1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Bud neck.
Protein: RL21_YERPA
Sequence: MYAVFQSGGKQHRVSEGQTIRLEKLDIATGETIEFDQVLMIANGEEINIGAPLVDGGKIKAEIIAHGRGEKIKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: DAPA_SYNE7
Sequence: MPQPYPFGRVITAMITPFNAEGQVAYDIAQSLAVHLVEQGSDGLVICGTTGESPTLTWEEELQLFRAVKEAVGDRAAVIAGTGSNCTREAIAATQSAATLGLNGSLQVVPYYNKPPQEGLYAHFRAIAEACPDLPLMLYNIPGRTGQSLQPETVARLASLPNVVAIKAASGNVEEVSALRQLLPDSFAIYSGDDSLTLPMLAVGAQGVVSVASHLVGPQLQALIQAFEAGNVARAQQLHHQLYPLFKALFLTTNPIPVRAAMELLGWSIGLPRLPLVPASAEIRQALASCLTELGLYTA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_RENSM
Sequence: MQVHVGRIGKPHGIRGEVTVEVLTDTPQERFSAGAVFSTEPTSAGPLTVETARWNKDILLLGFEEVNDRNRAETLRGTRLIFETDSVASDESESDSWYEHELIGLEARVGDQTVGKVSALNPMPAQDLLVITTAAGEEVLVPFVAEIVPEVDIAAGFIRLVPPGGLFDINRKDAE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLPA_METBF
Sequence: MPEVKRLSDGIFEVIKDKKQLATKNLDPGKTVYGEKLIAVEGVEYRTWDPRRSKLGAMVLKKFNIPLTKNSKVLYLGAASGTTVSHVSDIVSEGAVYAVEFAPRSMRDLIGLASRRKNIHPILADAGKPDSYSHLVEPVDLIFQDVAQPNQAEIAARNAVRFLKREGYLLLSIKARSIDTVAKPKEVFKAEVKKLEQAFEPRFEILNAKDLMPYHEDHLGVLAKLK
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: CTR4_MOUSE
Sequence: MARGLPSTACLARFCQKLNRLKPLEESSMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHLGVWQVPFLAHYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISLIVILFIIVLGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLSLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQVFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLLAYTFVATSIIVLRFQKASPPSSPCLASPGPTAKKYDSFSDHIQLVGAEQTSMSEPGQLRPALKPFLGFLDGCSPGTAVAWALGILVASAISLACVLVFGNSDLHLPQWGYVLLLVISGAVFLSSLLVLGAHQQQKKQDTFQIPLVPLTPALSILLNTCLMLKLSYLTWLRFIFWLLVGLVVYFGYGIWHSKENQREPLELTTAHYVVFPSGSLEETVQAVQPSSQSPVRESGCTE
What is the function of this protein?
Involved in the transport of the cationic amino acids (arginine, lysine and ornithine).
What are the official names of this protein?
Cationic amino acid transporter 4, CAT-4, CAT4, Solute carrier family 7 member 4.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPD_IDILO
Sequence: MKSESESHAQSQIDSLMAVIPAAGSGSRMQANIPKQFLMVANRTLLEYSIEAVLKDARVEQVFVAVSDSNAEYLIELKKSLPTKVHFVTGGNSRAESVLAGVKVAVSQGATHVLVHDAARPCLPKKALTAVINTGLKDPQGAILAIPVRDSLKRAVISVNDETGVTHIESSVDREALWQAQTPQVFNAERLQQAIEHMGALNPQLTDEASAMQWCGFQPALIPGSIRNLKVTHPEDFECVRDWLLADNNDHKN
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.