PharMolix/UniProtQA huggingface dataset:
Protein: BSND_RAT
Sequence: MADEKTFRIGFIVLGLFLLSLGTFLMSHDRPQVYGTFYAMGSIMVIGGVLWSMCQCYPKITFVPADSDFQGMLSPKALSLLETGLSEVKSPQPPYVRLWEEAAYDQSLPDFTHIQMKVMGYSEDPRPLLAPELKTGTSSAKEGEPHSAQTWMEAAVVVHRELDEKEGEKSRSQSSPPACSQGSAPLASFHDDLDVGSSEGRSPQPSPPDRDEAHLQVPWASRGPLDRFGDFALIDDTPISEDMGLEGQAQEEALPSKQPWSLRMKEETVQAGAEEPEQEEEDLYYGLPDSPGDPLPDKELGFEPDVQG
What is the function of this protein?
Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels.  In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux.  In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
What are the official names of this protein?
Barttin.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral.
Protein: RKD2_PYRCJ
Sequence: MDFPKVLLIRHFTEVLGMKYAGEGGEVLWFEEGLNRVAVGIYFTDLYEEAELYKRVGALMGLGASKVFLAVLPDALAFVDPRYFKANGVGLVVVDPAKGVDGVEVKIFARARPAAVEPLKIDAVKAALHEYLASELKRVEESLFEKVRRYVDQRVEEVKRALQAVEEAKRAAPPVQRAAAESAQEPRGGIGENEWVKILRSKR
What is the function of this protein?
Part of an actin-like archaeal cytoskeleton (PubMed:21414041).  Prevents polymerization of crenactin filaments by binding its C-terminus into crenactin's hydrophobic groove.  May act by competing with the D-loop of the following crenactin subunit for the hydrophobic groove (PubMed:27852434).
What are the official names of this protein?
Arcadin-2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Localizes between segregated nucleoids.
Protein: RLMN_YERPG
Sequence: MSEQLLTASTPIDAAPLSDNTVQTTAPATSKINLLDLNRQQMREFFAEMGEKPFRADQVMKWMYHYCYDDFEQMTDINKGLRAKLQRVAEIRAPEVAEEQRSVDGTIKWAIKVGDQQVETVYIPEADRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIIGSLKSTGTRPITNVVMMGMGEPLLNLNNVVPAMDIMMDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPTDDIRDEIVPINRKYNIETFLAAVRRYLDKSKANGGRVTVEYVMLDHINDSTEQAHQLAECLKDTPCKINLIPWNPFPGAPYGRSSNSRVDRFSKVLMEYGFTTIVRKTRGDDIDAACGQLAGEVIDRTKRTLKKKMAGEPIAIKTV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_METS4
Sequence: MDRAAKADLVASLNEVFSTTSLVVVAHYKGLTVADMQKLRRQMKQAGATVKVAKNRLANIALDGTNVASIKPLLKGPTLLAYSSDPVAAAKVAVDFAKGNDKLVILGGAMGATALNPDGVKALATLPSLDELRAKIVGLVQAPATKIAQVVNAPAAKLARVFGAYADTANKDEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GLPE_PSEPF
Sequence: MSEFKRIPPEQAQALREQGAVVVDVRDPATFAALHISGSKHLDNHSLHAFIQGADLDAPTVVVCYHGNSSQGAAAYLVSQGFSDVYSMDGGFELWRTTFPSETAQGTSE
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGYF1_HUMAN
Sequence: MAAETLNFGPEWLRALSGGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEELQDKEFAAVLQDEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLAGTSRGRGSTRSRGRGRGDSCFYQRSIEEGDGAFGRSPREIQRSQSWDDRGERRFEKSARRDGARCGFEEGGAGPRKEHARSDSENWRSLREEQEEEEEGSWRLGAGPRRDGDRWRSASPDGGPRSAGWREHGERRRKFEFDLRGDRGGCGEEEGRGGGGSSHLRRCRAPEGFEEDKDGLPEWCLDDEDEEMGTFDASGAFLPLKKGPKEPIPEEQELDFQGLEEEEEPSEGLEEEGPEAGGKELTPLPPQEEKSSSPSPLPTLGPLWGTNGDGDETAEKEPPAAEDDIRGIQLSPGVGSSAGPPGDLEDDEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSAAATALPLSHGAARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVPFAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQQFLQLVSSRQLPQCALREKAALGDLTPPPPPPPQQQQQQLTAFLQQLQALKPPRGGDQNLLPTMSRSLSVPDSGRLWDVHTSASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRREEKRRQQQQEEQKRRQEEEELFRRKHVRQQELLLKLLQQQQAVPVPPAPSSPPPLWAGLAKQGLSMKTLLELQLEGERQLHKQPPPREPARAQAPNHRVQLGGLGTAPLNQWVSEAGPLWGGPDKSGGGSSGLGLWEDTPKSGGSLVRGLGLKNSRSSPSLSDSYSHLSGRPIRKKTEEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSATGSLDVPMAVAILKEVESPYDVHDYIRSCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQEAWLSSASLQTAFQANHSTKLGPGEGSKAKRRALMLHSDPSILGYSLHGSSGEIESVDDY
What is the function of this protein?
May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling.  May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1 (By similarity).
What are the official names of this protein?
GRB10-interacting GYF protein 1, PERQ amino acid-rich with GYF domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the GIGYF family.
Protein: ASNA_SALEP
Sequence: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAEVHKQFGLAPFLPEQIQFVHSQELLSRYPDLDAKGRERAIAKELGAVFLVGIGGKLSDGHRHDVRAPDYDDWSSASELGYAGLNGDILVWNPVLEDAFELSSMGIRVDADTLMRQLALTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAQVRESIPAIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_CHLL3
Sequence: MAHKKGGGSTKNGRDSNPKYLGVKAAGGSTVSAGTIILRQRGTVIKPGTNAGIGRDHTIFSLVDGVVTFRNGRNNKKQVDILPS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SIDN_EPIFI
Sequence: LVAQAVKRHATAELPRHMVPDVFMPLNCLPRNQSSKVNRKRLLEVVGREWSMQPMSPVADEQVDPAWCIKHRPLLEKIQGVIKIMPKTLSRSTTLSELGVDSIGAIRLSSRFKNDGHDISAIQVLDSVTIEDLNNHLSVKRQGTSNWKTLLSRYLDHWKPLVSRHLARDPAHFSLVPTTVFQDGMLVETLRDPMLYWASYSWRLPSTVDIARVRQAWQHVSKNHDILKVSFVPTAYFEQEETQSSGPSSMFIQLIDYNASMDWQEIVSDSGDWQQSIQAVCANLQRTQHENNFSSPPWRVTILAQQDQRIMNLTIHHSLCDGEMLRSLMHDVAWAYSTAELPVKRCQVQEAVSRLAVRYSEPEGHKFWGDMLSPLVSQTSLGDATSNSPKAVVRKIRHRTTELQATRSTSKLTGLARRLGASSLSPLFRVTFGIMLTEYYEQQSVLFGEVRSERLLESQLVGAMAPLSATYPVPFRSSGNIKDMVHSQQILVMDSIRYGPPQPSDVRKILKKSRDEALYSAVYVLRQRPEDDGGSLAPWEEFKDIFEIFVDHEFALNVLEGADDTVTISLSVDETLMSSSAQAIFLQQLDALLIAFDKSAPEISLSGLNAHFPLDLLSIASSKVSAQYTSTVPPSHYIETWAKTHPEWKAVEVATGFLGSQKIVTEDWTYKKLNETANQVANLIIHASLHGRAIAVSLDRSLIAFAIIVGIMKSGNTYVPIEAGLPNDRKSFLLRDSRAAMAFVCDNNFDGVELPPETKVLDTKNQSFIENLSTQDTSDILNNYPENLDAYLLYTSGSTGTPKGVRVSRHNLSSFSDAWGKLIGNVAPKSLELGGVGKFLCLASRAFDVHIGEMFLAWRFGLCAVTGERLSMLDDLPRTFRELGVTHAGIVPSLLDQTGLVPEDAPHLVYLGVGGEKMTPRTQQIWSSSDRVALVNVYGPTEVTIGCSAGRILPDSDTRCIGHPLGDSVAHVLAPGSNEHVKKGMAGELVIEGSLVANGYLNRPDAKGFCDINGRKMYRTGDIVRMDADSSILFLGRKDEQVKVRGQRLELGEVSEVIRSLSPTDIDVVTLLLNHPGTSKQFLVSFVASSGAAVRGELRWINENYKEINNSLRQACEQTLPAYMVPDFIIPISFIPLRDTSAKTDAKALEHMFHTLSLGELFGESSSLVNKPTTAPSRDLTSIEKQILTVVKSVVGQDDKRDTRPRSTLFQLGLDSIASVKLSFKLKKLGFSTTVARLLQNPTIEELGRMKNALKESHDAEPSNSESITTRFEELEKKTMNSLKDRETTHIESIRPCMPLQEVLVAHTMSHGSEADNAYVSHMIFELDPAVVVEHVKAAWAAVVKNTELLRTCFIDRENDIVQLVIKENHATPVWKHLSNGTNMLKEELLSCKKEIADDIVTNIDKSPPVRFTLASCDGADETNEMSLFMLSIHHALYDMVSIEMIFQDFEVAYTDSSLPRRPSTLPLLEHIAAQQQNESKAKSYWTTLFDGYDHRIEKISPRTAQTTARTLNASLTTLESLCSQTNMTLSALIQGVFAYVLARTLKRPDLIFGVVLSGRSIDVEGIDAMAAPCISTIPQRLNIGTDGETIAELITTVQDRLFKSMEYQYTSLRSLSRWLEISGPLFSSLFSFTKLSPPEDSGSSKSRILKPTEGEMFLDFELALECEADPGTDTVTLRTRSTMFDKMEELDALLEQMESLVTSFTRGENKAVDGDFGSMLHTRLLPPHGSLQEESDDWSVLEQQIRDVVVAFSGALPNEVKRTTPFIKYGIDSITTIRFSTLLRKNGFWVSGADVLRNPSVAKLATHIQTTSSFNGTAKDSDNEASEPAGIGNWSKALLAGAVSTKVLDDVVAVYPLTPLQAGMISATVMMDPTLYAHHHPFRLPQGTSIDQVRSAWSRLVAKHDILRTSFHEINQPRPQLVGAVHQ
What is the function of this protein?
Nonribosomal peptide synthase required for the biosynthetis of epichloenin A, an extracellular siderophore that plays a crucial role in endophyte-grass symbioses (PubMed:23658520, PubMed:19923209).  SidN assembles epichloenin A by activating and incorporating three trans-anhydromevalonylhydroxyornithine (trans-AMHO), 1 glutamine and 4 glycine moieties (PubMed:23658520).  Trans-AMHO is produced from L-ornithine via 2 steps involving a L-ornithine N(5)-monooxygenase and an AHMO-N(5)-transacylase that have still to be identified (PubMed:19923209).  The third adenylation domain (A3) of sidN incorporates the hydroxamate groups of the siderophore which forms an octahedral iron complex (PubMed:19923209).  The other component amino acids are assembled by sidN adenylation domains A1 and A2 (PubMed:23658520, PubMed:19923209).
What are the official names of this protein?
Nonribosomal peptide synthase sidN, NPRS sidN, Epichloenin A synthetase, Extracellular siderophore synthetase N.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: GLK_CUPMC
Sequence: MTDRAMSYPRILADVGGTNVRFAMETAPMRIGEITAYKVAEHASLEAAMRLYMLTRSGAARPRHAAIGLANPVTGDQVKLTNHNWAFSVEAMRRALDLDTLVAINDFTSLALALPYLPDASLVQVRDGTAVATAPRALIGPGTGLGVSGLIPAPGGAVALAGEGGHIEIMPVTDDEWIAWRAAHDQFGRVSAERLLSGMGLSHIHAALSAEMGTPLEVPLAPAQVTDGAMRAGDPVCRRAFDAFCGMLGSVAADVALVLGARGGVYLGGGIVPRFVDALRASTFAERFVAKGRMGSFLADVPVYVITAEYPALPGLARALADRLEADARRAETSQS
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_HYDS0
Sequence: MKVNVIGAGLAGSEAAYFLANKGIKVRMFEMRPITSHFTSRQDEKTGTHDVRNATQTRPITTTEAHKTDKFGELVCSNTLGSFEITTGAGLLKKEMELLNSLVIKAAKHSYVKAGSALAVDRNEFSDFITKTILSHPNIEVVREEVESLNENELNIVATGPLTSEKFSKYLKNLITDDYLYFYDAIAPIVEASSVDFSKGFWGSRYDKGDDYFNCTMTKEEYDIFYNELLKAEKVPTKDFERVVHFEGCLPIEEIASRGYETLVFGPMSPKGLKHHISKDVYAIVQLRKETKEGEALSLVGFQTKLTYKEQVRVFRLIPCLRNAVFSRLGSMHRNTFLQSNKLLKPTLELRKNPNILFAGQITGVEGYSASAATGIIAGINAWLKLEGKEPTTPPKTTMLGALLDYISSKEGELQPMNPVFGLLPDIEVHKKHKKLLKAYRALFDMKKFIEHHKIYD
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_ACIB5
Sequence: MKISLSLQQDFRSPELELKRAQLKKIIETTLRHVGYKEDCEIGIACVDLEESHQLNLQYREKDKPTNVLSFPSDIPEEVLPMLDALPLGDLVICIPVVLQEALEQKKTAQNHFAHLLVHGVLHLLGYDHETSDEDAEEMEGLEIEILAKLNIANPYQE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_ACTPJ
Sequence: MRGKFIVLEGLEGAGKTTAHQVILAQLEKAGKNVVQTREPGGTPLAEKLRHLIKHETEEAVSDKAELLMLYAARIQLVENVIKPALAEGKWVLGDRHDMSSQAYQGGGRQIDRHLLETLKETVLGNFEPDLTIYLDIDPAVGLARARGRGELDRIEQQSLDFFYRTRQRYLELTQNNEKAVIINAEQSIEQVAADIQQAVENFLKIAK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RIBB_SALCH
Sequence: MNQTLLSSFGTPFERVELALDALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRVTTVRAAIKDGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIAFAGQHNMAVVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: RSMH_BACAH
Sequence: MFNHVTVLLKETVDGLDIKPDGTYVDCTLGGGGHSSYLLSQLTEGGRLIAFDQDEIAIQNAKEKFSSYGEQFITVKSNFRYLSEKLQELGITEVDGILFDLGVSSPQLDTPERGFSYHHDAPLDMRMDQDAPLTAYDVVNSWSYEQLVRIFFQYGEEKFSKQIARKIEAYRENKAIETTGELVELIKEGIPAPARRTGGHPAKRVFQAIRIAVNDELKVFEEALESAIEMVKPGGRVSVITFHSLEDRICKTTFKRNSTTPQLPPGLPIIPDEFKPKLKLITRKPILPSDIELEENNRARSAKLRIAEKR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSPH2_GLOBR
Sequence: MVLIRVLANLLILQLSYAQKSSELIIGGDECNINEHRSLVLMYYDGHQCDGTLINEEWVLTAAHCDGENMEIQLGVHSKKVPNEDVQTRVPKEKFFCDSNKTYARWNKDIMLIRLDRPVSNSAHIAPLSLPSSPPSVGSVCRIMGWGTFSTTQETYPDVPHCANINIHDFEVCQAAYPGLPATNRILCAGILEGGKDTCKGDSGGPLICNGEIQGIVSWGGHLCGNVLEPGIYTKVFDHLEWIRSIIAGNTDATCPL
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease Haly-2, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PG147_MONPV
Sequence: MITLFLILCYFILIFNIIVPAISEKMRRERAAYVNYKRLNKNFICVDDRLFSYNFTTSGIKAKVAVNKNVPIPCSKINEVNNKDVDTLYCDKDRDDIPGFARSCYRAYSDLFFTT
What is the function of this protein?
Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry.  Also plays a role in cell-cell fusion (syncytium formation).
What are the official names of this protein?
Virion membrane protein OPG147.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG147 family.
Protein: PTHR_SHEEP
Sequence: VGVFLLSYSVPSCGRSVEELGRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPAPNTKNHPVRFGSDDEGKYLTQETNKVETYKEQPLKTPGKKKKGKPG
What is the function of this protein?
Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport.  Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth.  Required for skeletal homeostasis.  Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs.  Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion.  BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath (By similarity).
What are the official names of this protein?
Parathyroid hormone-related protein, PTH-rP, PTHrP.
What is the protein family that this protein belongs to?
Belongs to the parathyroid hormone family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted.
Protein: HRTA_STAHJ
Sequence: MALQLKHITKTFGNGDAQTEVLKNINFSVNQGEFIILSGASGSGKSTLLNILGGLLSPSSGDVLYKGENLFSKEVDKTSLRLNDIGFIFQSSHLVPYLTVREQLMIVAKEAGIKRKEAKDKAQRLLNEIGLSHRLDVYPHLLSGGEKQRVAIMRAFMNEPKIILADEPTASLDADRATSVVQMIKAHVQTKNMIGIMITHDKRLFEYADRVIEIQDGKIEL
What is the function of this protein?
Part of the ABC transporter complex hrt involved in hemin import.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative hemin import ATP-binding protein HrtA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. HrtA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FMT_ELUMP
Sequence: MKTIFFGTPEVAVPYLEILNRYTEVVLVVTQPDRPRGRGMVITPCPVKETALKMGLKVLSPEKITDIEADLKAAGADYGIAVAYGQILKQHIIDIPKLGIVNIHFSLLPKFRGAAPVQHTLFAGETKTGVTAFWIDKGMDTGPVFAYKETDILPSEDAKTLFTKLISLGGILLEDVIEYIRLGQIVKIPQTKNIFTPQEDGSMFKEELPLPTYAPMIKKEDTILDFNNFGAETFFNRVRGLACGPHAKVITKINGKEDLLQIIKASLLEKNKQCPPNMPRGSVVSIENDGRILVKCYDSCIYIDIVRPAGKKDMTAASFANGHKIKPGDVIFY
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GCST_THEPX
Sequence: MDNLKKTPLFELYKKYNGKIIDFAGWALPVQFESIISEHEAVRNAAGLFDVSHMGEITVKGREAFNFLQNLITNDLSKLKGNQVLYTFMCNYNGGVVDDLLVYKYSDEHFYLVVNAANIEKDYKWMKDNKGVYEVEIENISDEVAELAIQGPKAEEILQKLTDTDLSEIKFFCFKDNVKIAGIECLVSRTGYTGEDGFEIYMPNKYAVELWEKIVEVGKEYGLKPAGLGARDTLRFEAGLPLYGNELSEEITPLEAGFEFFVKFDKGNFIGKDALLKQKEEGLKRKIVGFEMIDNGIPRHGYEVRAHNQKIGYVTTGYFSPTLKKNIGLALIDSKYAQLGNQIEIVIRNKPLKALIISKNFYKKNYKK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: TRUD_SALCH
Sequence: MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRGLINTMGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: Y3315_SERP5
Sequence: MTSKPSGSVSWFQVFQRGQHYMKTWPSDKRLAPVFPENRVASATRFAVRFMPPLAVFTLTWQIALGGQLGPAIATALFACSMPMQGLWWLGRRSVTPLPPTLLQWFHEVRNKLAEAGQAVAPVEGTPTYQALADLLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein Spro_3315.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS21_STAA8
Sequence: MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: YTJA_SALA4
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIVLFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPB_PSEAB
Sequence: MRRIAVVGAAGRMGKNLIEAVQQTGGAAGLTAAVDRPDSTLVGADAGELAGLGRIGVPLSGDLGKVCEEFDVLIDFTHPSVTLKNIEQCRKARRAMVIGTTGFSADEKLLLAEAAKDIPIVFAANFSVGVNLCLKLLDTAARVLGDEVDIEIIEAHHRHKVDAPSGTALRMGEVVAQALGRDLQEVAVYGREGQTGARARETIGFATVRAGDVVGDHTVLFAAEGERVEITHKASSRMTFARGAVRAALWLEGKENGLYDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TZAP_HUMAN
Sequence: MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVLACCSHFFQSLYGDGSGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAARELRVPEAVELCQSFKPKTSVGQAAGGQSGLGPPASQNVNSHVKEPAGLEEEEVSRTLGLVPRDQEPRGSHSPQRPQLHSPAQSEGPSSLCGKLKQALKPCPLEDKKPEDCKVPPRPLEAEGAQLQGGSNEWEVVVQVEDDGDGDYMSEPEAVLTRRKSNVIRKPCAAEPALSAGSLAAEPAENRKGTAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRVHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPHVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDEKMVVVALQPPAELEVGSAEVIVESLAQGGLASQLPGQRLCAEESFTGPGVLEPSLIITAAVPEDCDT
What is the function of this protein?
Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411).  Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat (PubMed:28500257, PubMed:28082411).  Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411).  Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257).  Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257).  Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177).  Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891).
What are the official names of this protein?
Telomere zinc finger-associated protein, TZAP, Krueppel-related zinc finger protein 3, hKR3, Zinc finger and BTB domain-containing protein 48, Zinc finger protein 855.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Note=Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat (PubMed:28500257, PubMed:28082411). According to a report, preferentially binds to long telomeres that have a low concentration of shelterin complex, competing with the telomeric repeat binding factors TERF1 and TERF2 (PubMed:28082411). According to another report, binds telomeres regardless of their length (PubMed:28500257).
Protein: RS11_STRT1
Sequence: MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAVAWSSAGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.