PharMolix/UniProtQA huggingface dataset:
Protein: Y213_MYCPN
Sequence: MKLSAIISLSVAGTVGTTAVVVPTTITLVNKTHQVEHESEQSDFQDIRFGLNSVKLPKAQPAAATRITVENGTDKLVNYKSSPQQLFLAKNALKDKLQGEFDKFLSDAKAFPALTADLQEWVDQQLFNPNQSFFDLSAPRSNFTLSSDKKASLDFIFRFTNFTESVQLLKLPEGVSVVVDSKQSFDYYVNASAQKLLVLPLSLPDYTLGLNYMFDHITLNGKVVNKFSFNPFKTNLNLAFSNVYNGVDVFEAQKNLVGKGKYLNTHVKAEDVKKDVNANIKNQFDIAKIIAELMGKALKEFGNQQEGQPLSFLKVMDKVKEDFEKLFNLVRPGLGKFVKDLIQSSSQAENKITVYKLIFDNKKTILNLLKELSIPELNSSLGLVDVLFDGITDSDGLYERLQSFKDLIVPAVKTNEKTAALSPLIEELLTQKDTYVFDLIQKHKGILTNLLKNFLADFQKSTPFMADQVAIFTELFDNEGAFDLFGEADFVDKIAELFLTKRTVKNGEKIETKDSLLVTSLKSLLGEKVAALGDLLDSYIFKNELLNRSVEVAKAEAKDTKGATDYKKEQAKALKKLFKHIGENTLSKTNLDKITLKEVKNTENVELEETETTLKVKKLDVEYKVELGNFEIKNGLIKAMLEFLPDTKDLETTLDKLLFKGESYKAMKDKYIKEGFPGYGWAKGVVPGAFESIENTFKSAIDKTKSIRDLFGDMLFGNDLSSVKETDSFITLGGSFDIKYGGENLNVLPAYYSLINSEIGYQIIGVDTTIDATKVKVELKNKEYKGKSPAINGQVKLSQSFFNVWTNMFDSITKQIFQKKYEFKDNIQVFARNEDNTSRLELDISDPEQRVIPFAFVDGFGIQLKAVDKNITKEAGNTEPKSPVIQLYEALNKEKDQKQQSKQSPKQLDTKTQLGYLLKLGDNWSKDDYKSLIDDTIINNNYLEASFNSKITVDRLGIPIDLWLFKIWPKFNLEIPMQGSLQLYSSSVIFPYGIYDTSVQDAAKIVKRLNFTDMGFKLNDPKPNFWFVGF
What are the official names of this protein?
Uncharacterized protein MG075 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ICAM1_PANPA
Sequence: MAPSSPRPALPALLVLLGALFPGPGNAQTSVSPPKVILPRGGSVQVTCSTSCDQPDLLGIETPLPKKELLLGGNNWKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVGKDLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVERDHHGANFSCRTELDLRPQGLQLFENTSAPHQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVLEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLMCAVILGNQSRETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPVGPRVQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQASGNPLPELKCLKDGTFPLPVGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPRYEIVIITVVAAAVIMGTAGLSTYLYNRQRKIRKYRLQQAQKGTPMKPNTQATPP
What is the function of this protein?
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).  During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity).
What are the official names of this protein?
Intercellular adhesion molecule 1, ICAM-1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. ICAM family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: H8E01_CYRHA
Sequence: MVNMKASMFLTFAGLVLLFVVCYASESEEKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCNGYVCSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1m, U3-TRTX-Hhn1m, Hainantoxin-VIII-5, HNTX-VIII-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YEL1_YEAS2
Sequence: MCASLNEVKKNETYGVSQKGYNDNFSESEGVLHGSKSMPTSMKNMLQSPTMVNMCDILQNKEAANDEKPVIPTTDTATAGTGTEDISSTQSEETDQNSHLIASEILEGTFKDISYKEYANFLGNDNNNQVLTEFVKLLSPLPSSLLETLFNLSKSIYFIAEAQNIDRILECLSKEWIACHPNTHWKSGYKSCHIVLFSLLILNSDLHNNFQVDHKKIKFSMVAFINNTLRALREENEYEELKIYSREHLIIEELSEYYKTLNETPLPLCTESRTSINTSDNQSSLKRFSTLGSREFSTSNLRSVNSNSTTLYSRDGQVSVREMSAKSNKNFHNNHPMDALYLKESFDDGLITENGSSWFMDDLILISKKSLPRKYSKRDKDQVAAPKMTSKRNKSFFGWLKPSKTTTLIEHTSRRTSLSYLNKDSEWERVKIQVKEGRIFIFKIKPDVKDIIQSSETDSATIDYFKDISSSYFAYSLLEAEAHVVQDNIIIGSGAMKSNVCNKNTKRKSGNFTVSFPENINGPKLVLEFQTRSVEEAHKFMDCINFWAGRISPVPLTQFEAVSNAEYGWSDKILTEHASLNLKNIVVSEWKPLLGLELLYEDAKDVEMVELKERLKELMNFTRQLGIWIDKHNEIKDKLVEIWSFDDNYFEAVMNNWNSRYLYMNNQYKKRLSYLKALQKAMGSVQF
What is the function of this protein?
Guanine nucleotide exchange factor for ARF3 required for localization of ARF3 to the bud neck and tip and involved in actin patch polarization.
What are the official names of this protein?
Guanine-nucleotide exchange factor YEL1, EFA6-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the YEL1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Bud neck. Bud tip. Note=Localizes at the cell membrane only at the bud neck and bud tip and this localization is ARF3-dependent.
Protein: RL20_STRP6
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVADAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: DUT_ICHVA
Sequence: MGEMTSGVDGHGSTKRTTSEAQKMDFNTDRGSAIPTGDDRGYQCGVIGDSVRFSVFTGYDAADVSIPKISSPGSAGFDLSVLEDREFIRGCHYRLPTGLAIAVPRGYVGIITPRSSQAKNFVSTGIIDSDFRGHIHIMVSAIADFSVKKNQRIAQLVVTPCLTQSEVVPYETLERTRRGTGGFGSSGQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RSMG_SHEDO
Sequence: MLSSQLSAYLAEMNLSATEQQQGQLVGFVEMLNKWNKAYNLTSVRSPEQMLIRHVMDSLTVSPYLSGKRFIDVGTGPGLPGIPLAIMNPDKEFVLLDSLGKRIRFQKQVQFELKINNISSVESRVEAFQPEIKFDGVLSRAFASVQDMLTWCHHLPHNEGIFYALKGQLNQVELEAIPEGFELLETIVLQVPQLDEQRHLLKLRKKLG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_RICAE
Sequence: MKKKLYEGSSKILYSAEEDFLLIMAFSDKAILETGEIVDISGKGVLNNNISSFLMDKLEMIGIENHFIEKINMREQLIQYVEVFPIQVIISSVACSRFVKEFGIDEGYVFDKPIIDFKVRSREFKYPIVNEYQILNFGWLTRDEIKAVKEQALRIYDFLSGLFIGVGIRLVECKLEFGRVFNGEESIIMLTDEISPDNCRLWHINSNEKLGFELLEKEPNKVFESYQLIADRLKEK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RS5_PSEPW
Sequence: MANNDQKRDEGYIEKLVQVNRVAKTVKGGRIFTFTALTVVGDGKGRVGFGRGKSREVPAAIQKAMEAARRNMIQVDLKGTTLQYATKAAHGASKVYMQPASEGTGIIAGGAMRAVLEVAGVQNVLAKCYGSTNPVNVVYATFKGLKAMQSPESIAAKRGKSVEEIF
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CLPX_DICT6
Sequence: MSDRDIRCSFCGRTQKEVKKLIAGPGVYICDECVKLAYDIIEEDEEEDVTEEFEDFVLPKPHEIKNFLDQYVIGQERAKKILSVAVYNHYKRIFMKSKITEDVEIQKSNILLIGPTGVGKTLLAETLAKFLKVPFAIADATTLTEAGYVGEDVENILLRLIQNADWDIKRAEKGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLRIVEGTIANVPPQGGRKHPYQEFIQINTKDILFIAGGSFEGIEKIVEKRLDVSSIGFGAQIEPKNRKSLTQILNHIIPEDLIKFGMIPEFVGRFPVVAVLEPLSEEALLKILTEPKNALVKQYKALLSIEGVEIDFTDEALRSIVKEALEKATGARGLRAVMEELMLDLMYELPNLGIKRFTITPELVYNRGKISQELLKKLAG
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: UBA4_LODEL
Sequence: MTDLSKEELLQRIQQLENENEQLKAVALQSLHTLRYNQSCSHSLQQSNSVNEEPLSLEEFKRYGRQMIVPKFGSLNAQKKLRSSKILVVGAGGLGSPALQYLCAAGIGEIGIIDDDTVDVSNLHRQIIHKSSLVGILKCESAKQSMKDLNPFVKVETYPERLTVFNAFEIIDKYDLVLDCTDHPAVRYLINDVCVLLGKTIVSGSGLRAEGQLTILNYDQVGPCYRCFYPQAPEPSSITSCSDGGVIGPAIGLVGVAMAMETIKLLTGTYTRENFTPFLASYSAYPLQQMKTFKMRPKQSSCKVCGDRPEITKEMVENGSIDYVSFCGHIDEKNPPLQKKYRITVQEYSSLLNSQSREHTLIDVRPKEQFEITNLPGSINLDWPLVFSKCDNDKIDLLLPQDITKADQLYVICRFGNDSQLATAKLIEAGYLNAKDIIGGLNKWSEDIDAAFPKY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1.  Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase UBA4, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_VIBPA
Sequence: MKRAFILVLDSFGIGATADAKEFGDVGSDTLGHIADQCEKGLADNDKRQGALRLPNLSKLGLAMAHKESTGRFAPGLDADAEIIGAYGHAAELSSGKDTPSGHWEIAGVPVLFDWGYFTDKANSFPKELTDRILERAGLDGFLGNCHASGTQVLDDLGEEHMKTGQPIFYTSADSVFQIACHEETFGLDRLLELCQIAREELEDYNIGRVIARPFIGPGKGQFERTGNRRDLSVEPPSATVLQKLVEEKQGNVVSIGKIADIYANCGITKKVKATGIPALFEATLEQIKEAGDNTIVFTNFVDFDSAYGHRRDVAGYAAALEYFDGRINEVLELMGEDDVLILTADHGCDPTWPGTDHTREHIPVLVYGQKVPAGSLGRRETFADIGQTLASYFGTSPMDYGKNFL
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUC2_MOUSE
Sequence: MMNGRPGHEPLKFLPDEARSLPPPKLNDPRLVYMGLLGYCTGLMDNMLRMRPVMRAGLHRQLLFVTSFVFAGYFYLKRQNYLYAVKDHDMFGYIKLHPEDFPEKEKKTYAEILEPFHPVR
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 subunit C2, Complex I-B14.5b, CI-B14.5b, NADH-ubiquinone oxidoreductase subunit B14.5b.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFC2 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: ZN487_HUMAN
Sequence: MASRPRPRTPSRGPSDLRFRGEAGLRRVFLKKAGGSVSFSDVAVGFTQEEWQHLDSAQRTPYRDMMLENYSLLLSVGYCITKPEVVCKLEHGQVLWILEEESPSQSHLDCCIDDDLMEKRQENQDQHLQKVDFVNNKTLTMDRNGVLGKTFSLDTNPILSRKIRGNCDSSGMNLNNISELIISNRSSFVRNPAECNVRGKFLLCMKRENPYARGKPLEYDGNGKAVSQNEDLFRHQYIQTLKQCFEYNHRGYTEERNPMNALNVGKLLDIGHALQYIKEHTRDKTYECNECGKNFCEKSNLHVHQRTHTGEKPYGCNECQKAFGDRSALKVHQRIHTGEKPYELHQRTHTGEKPYACSECGKTFYQKSSLTTHQRTHTREQPYEYNESFYQNPNFTKCQRDNIEETLVNILKAQKPSPSWTRSIAETTQVGGSVSLKDVTVDFTQEEW
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Putative zinc finger protein 487, KRAB domain only protein 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TADA3_BOVIN
Sequence: MSELKDCPLQFHDFKSVDHLKVCPRYTAVLARSEDDGIGIEELDTLQLELETLLSSASRRLRVLEAETQILTDWQDKKGDRRFLKLGRDHELGAPPKHGKPKKQKLEGKAGHGPGPGPGRPKSKNLQPKIQEYEFTDDPIDVPRIPKNDAPNRFWASVEPYCADITSEEVRTLEELLKPPEDEAEHYKIPPLGKHYSQRWAQEDLLEEQKDGARAAAVADKKKGLMGPLTELDTKDVDALLKKSEAQHEQPEDGCPFGALTQRLLQALVEENIISPMEDSPIPDMSGKESGADGASTSPRNQNKPFSVPHTKSLESRIKEELIAQGLLESEDRPAEDSEDEVLAELRKRQAELKALSAHNRTKKHDLLRLAKEEVSRQELRQRVRMADNEVMDAFRKIMAARQKKRTPTKKEKDQAWKTLKERESILKLLDG
What is the function of this protein?
Functions as a component of the PCAF complex.  The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context.  The PCAF complex could be considered as the human version of the yeast SAGA complex.  Also known as a coactivator for p53/TP53-dependent transcriptional activation (By similarity).  Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).
What are the official names of this protein?
Transcriptional adapter 3, ADA3 homolog, Transcriptional adapter 3-like, ADA3-like protein.
What is the protein family that this protein belongs to?
Belongs to the NGG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA_BACLD
Sequence: MLGILNKVFDPTKRTLSRYEKKANEIDALKADIEKLSDEALKQKTIEFKERLEKGETVDDLLVEAFAVVREASRRVTGMFPFKVQLMGGVALHEGNIAEMKTGEGKTLTSTMPVYLNALSGKGVHVVTVNEYLASRDAEEMGKIFEFLGLTVGLNLNSLSKDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAFVRTLKADQDYTYDVKTKGVQLTEEGMTKAEKAFGIENLFDVRHVALNHHIAQALKAHAAMHKDVDYVVEDGQVVIVDSFTGRLMKGRRYSDGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNKPIARDDRPDLIYRTMEGKFKAVAEDVAQRYMVGQPVLVGTVAVETSELISRLLKNKGIPHQVLNAKNHEREAQIIEDAGQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMKRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDARKQLLQYDDVLRQQREVIYKQRFEVIDSDNLRSIVENMIKASLERAVASYTPKEDLPEEWNLDGLVELVNANFLDEGGVEKSDIFGKEPEEITELIYDRIKTKYDEKEERYGSEQMREFEKVIVLREVDTKWMDHIDAMDQLRQGIHLRAYAQTNPLREYQMEGFAMFENMIAAIEDDVAKFVMKAEIENNLEREEVIQGQTTAHQPKEGDEEKQAKKKPVRKAVDIGRNDPCYCGSGKKYKNCCGRTE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RS3_SULTO
Sequence: MVLVKKYFLQRSMTKVMVDEYLAKQFYNAEYAGVEIVKTPIGTRVIIYAGRPALIIGKGGKTIKQLAQMLERYFGLDNPQITVTSVENPELNARVMAFRLAIALEKGYHFRRAAFITIRRIMNAGALGAEVIISGKLTSERAKYEKLKEGVVYKSGAFLDKIVDRAVAIAMLKPGVYGVEILITKPMKSVDKIELREQPKGPGENMVTVTNVSFIEESQKSGEQK
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL25_BIFLS
Sequence: MATTIKLEGEARSEFGKGVARRLRVANKIPATIYAGGEEPAFVTLPMRETTLALRHTNALFTIAFDGNTKMAVVKDVQKNPVKRIIEHIDFLEVKAGEKIDVEVPVFVEGTPKGAAVAFVDIQELKVRADVTNLPEKIVVSVEGLTDGTKVFAKDVVLPEGVELDIEDPEESVVTVEVPEDATESTTAPEAAAAPADAAAAPAADAK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: APT_STRZP
Sequence: MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYATDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIGDYDYKVLMHY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_MYCPA
Sequence: MVSVPTGLRPSAVPGVRLPALADQVGAVMAGPDRRAAVPDVTVTGVTLRAQDVLPGDLFAALPGATTHGARHAAEAIERGAVAVLTDAAGVAQLTGGRTTPTLLHPRPRSVLGQLAAAVYAHPSERLTVIGITGTSGKTTTTYLVESGLRAAGRTAGLIGTVGIRIDGADIPSALTTPEAPALQALLAAMAEQRVDTVVMEVSSHALALGRVDGTRFAVGGFTNLSRDHLDFHPTMADYFEAKALLFDPNSPLRAHRAVVCIDDEAGREMAARAGDAVTVSAEGQPAHWRAVEVAPLGTGGQQFTVIDPAGVQHRAGIRLPGHYNVANCLVALALLDAVGVSPEQAAPGLLQTRVPGRMEEIDAGQDFLALVDYAHKPGALRAVLSSLKRPDRRLAVVFGAGGERDPGKRAPMGATAAELADLVVVTDDNPRGEDPAAIRREILAGVTESGCAAEVVEIGDRRAAIRHAVAWAGPGDVVLVAGKGHETGQRTGEHTRPFDDRVELAEALREAVGPRKAQG
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y956_TREPA
Sequence: MKHPSVRVCCFAFASCLLCAGCSLKRLAFSSLSHTLAPFPEGELDAHLSDADFTRVFTEEDDLDLVAQSLPLVLKVYEALHLQNPAHRGLSLAVGRLYIMYANAFVQTPAQYLPEDEFEAQNEAYSRARKLYLRGARYALSSLETAYPGFTREVFSGDEQRLHKVLSRCTRVDVGTLYWVGTGYVAAFALTPLGSALPDTVHAAVMMLERACDLWPSYQEGAVWNVLTKFYAAAPESFGGGMEKAHTAFEHLTRYCSAHDPDHHITYADALCIPLNNRAGFDEALDRALAIDPESVPHNKLLVILSQKRARWLKAHVQDFFLD
What are the official names of this protein?
Uncharacterized protein TP_0956.
Protein: LEU3_LEPIN
Sequence: MKNVAVLSGDGIGPEVMEIAISVLKKALGAKVSEFQFKEGFVGGIAIDKTGHPLPPETLKLCEESSAILFGSVGGPKWETLPPEKQPERGALLPLRKHFDLFANLRPAIIYPELKNASPVRSDIIGNGLDILILRELTGGIYFGQPKGREGSGQEEFAYDTMKYSRREIERIAKVAFQAARKRNNKVTSIDKANVLTTSVFWKEVVIELHKKEFSDVQLNHLYVDNAAMQLIVNPKQFDVVLCENMFGDILSDEASIITGSIGMLPSASLSESGFGLYEPSGGSAPDIAGKGVANPIAQVLSAALMLRYSFSMEEEANKIETAVRKTIASGKRTRDIAEVGSTIVGTKEIGQLIESFL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESR2_ONCMY
Sequence: MHQQSPVDDVTALNSSALTMSEYPEGESPLQLQDVDSSRVGGHILSPIFNSSSPSLPVESHPVCIQSPYTDLGHDFTTLPFYSPALLGYGTSPLSECSSVRQSLSPTLFWPPHSQVSSLALHQQHTRLQQNHPTGGTWTELTPHDHSEEEYRKPLVKRVADAEETSTSLRGKADMHYCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMMKCGLRRDRGSYQQRGAQQKRLARFSGRMRTSGPRSQEMKSVPCPLSGNEVVNMALTPEELIARIMDAEPPEIYLMKDMKKPFTEANVMMSLTNLADKELVHMISWAKKVPGFVELSLFDQVHLLECCWLEVLMLGLMWRSVNHPGKLIFSPDLSLSRDEGSCVQGFVEIFDMLLAATSRFRELKLQREEYVCLKAMILLNSNMCLSSSEGGEELQRRSKLLCLLDSVTDALVWAISKTGLSFQQRSTRLAHLLMLLSHIRHLSNKGMDHLHCMKMKKMVPLYDLLLEMLDAHIMHGSRLSHSGPAPKESTGVQEATLSVLKNDL
What is the function of this protein?
Binds estrogens with an affinity similar to that of ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
What are the official names of this protein?
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MED7_AEDAE
Sequence: MENTDAIQVSSFPLPPAQYYKLYTDENVRNNRAPKPPAPIQGTYQMFGQQFSTEDNIIRPLEAQGFKRLYPQHFDRRKELKKLNHSLLVNFLDLIDLLVHNPDSPQRAEKIEDLNLLFVHIHHLLNEFRPHQARETLRVMMELQKRQRQETTQRFQNHLEKVREMVNNAFASLPDPAESDRLNSTVEPMDTGDDGEAGKSRGEGCHPLDRLMCELVDKM
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MLTF_PSEA7
Sequence: MFALTAYRLRCAAWLLATGIFLLLAGCSEAKAPTALERVQKEGVLRVVTRNSPATYFQDRNGETGFEYELAKRFAERLGVELKIETADNLDDLYAQLSRAGGPALAAAGLTPGRQDDASVRYSHTYLDVTPQVIYRNGQQRPTRPEDLVGKRIMVLKGSSHAAQLAELKKQYPELKYDESDAVEVVDLLRMVDVGDIDLTLVDSNELAMNQVYFPNVRVAFDFGEARGLAWALPGGDDDSLMNEVNAFLDQAKKEGLLQRLKDRYYGHVDVLGYVGAYTFAQHLQQRLPRYESHFKQSGKQLDTDWRLLAAIGYQESLWQPSATSKTGVRGLMMLTNRTAQAMGVSNRLDPKQSIQGGSKYFVQIRSELPESIREPDRSWFALAAYNIGGAHLEDARKMAEKEGLNPNKWLDVKKMLPRLAQKRWYAKTRYGYARGGETVHFVQNVRRYYDILTWVTQPQMEGSQIAESGLHLPGVNKTRPDDDEGDGKL
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: VPX_HV2ST
Sequence: MAGPRETIPPGNSGEETIGEAFEWLDRTVEAINREAVNHLPRELIFQVWQRSWRYWHDEQGMSISYTKYRYLCLMQKAMFIHSKRGCTCLGGGHGPGGWRSGPPPPPPPGLV
What is the function of this protein?
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells.  Targets specific host proteins for degradation by the 26S proteasome.  Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1.  This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1.  In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription (By similarity).
What are the official names of this protein?
Protein Vpx, Viral protein X, X ORF protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus VPX protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Nuclear just after virion uncoating, or if expressed in the absence of unprocessed GAG.