PharMolix/UniProtQA huggingface dataset:
Protein: AAK1_BOVIN
Sequence: MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKVITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPTKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKTQPPPSQPLPQSQPKQPQAPPTSQQPPSAPAQALPTQAQATPQHQQQLFLKQQQQQQTAPPAQQPAGTFYQQPQQQAQAPQFQAVHPAAQQPVIAQFPVVSQGSSQQQLIQNFYQQQQQQQQLATALHQQQLLTQQAALQQKTTAAAAPQPQAQPAAAASPAPAQEPAQIQAPVRQQPKVQTTPPPTIQGQKLGSLTPPSSPKAQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRASQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLGEGKYPEKLGGSAESLIPGFQPTQGDAFAASSFSAGTAEKRKGGQTMDSSLPLLSVSDPFIPLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIEKADVAVESLIPGLEPPVPQRLPSQTESVTSNRTDSLTGEDSLIDCSLLSNPTTDLLEEFAPIAISAPAHKAAEDSNLISGFDVPEGSDKVAEDEFDPIPVLITKNPQGGHSRNSSGSSESSLPNLARSLLLVDQLIDL
What is the function of this protein?
Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis.  Preferentially, may phosphorylate substrates on threonine residues.  Regulates phosphorylation of other AP-2 subunits as well as AP-2 localization and AP-2-mediated internalization of ligand complexes.  Phosphorylates NUMB and regulates its cellular localization, promoting NUMB localization to endosomes.  Binds to and stabilizes the activated form of NOTCH1, increases its localization in endosomes and regulates its transcriptional activity.
What are the official names of this protein?
AP2-associated protein kinase 1, Adaptor-associated kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Membrane, clathrin-coated pit. Presynapse. Note=Active when found in clathrin- coated pits at the plasma membrane. In neuronal cells, enriched at presynaptic terminals. In non-neuronal cells, enriched at leading edge of migrating cells (By similarity).
Protein: ABDA_TRICA
Sequence: MSSKFIIDSMLPKYHQQFHHQQLFQSATTEAPAAYSSSSPSGSSPQHSSSSASTSPAARMYPYVSAAHHHHQAAAAAFGAAASGSMVPSFSSTASSALAAAVDAATDKSCRYTAGLAANVTPADSMVNYTLGQHHHNGAAVSAASSVSAASASMAVAAQFYHQAASAVVDPLNSCSQPAAPGGQPIPDIPRYPWMSITDWMSPFDRVVCGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARREREEQERHKQQQQEKQQKIEQQTHSSIHQHHHDPMKMSLDKSGGSDLLKAVSKVPT
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein abdominal-A homolog.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBA4_ASPFC
Sequence: MENLEQTCASLRAQIAATEAQLAGLKRELEIAEQAAEVKAQSTTRTITAEDGKTNETREWPLLSEEYKRYGRQMIVPQLGLQGQLKLRAARVLIVGAGGLGCPAALYLAGAGVGTLGLVDGDTVENSNLHRQVLHSSKNVGTFKVDSAIEYLRELNPHPTYVPYRAHLTPQEAPGIFKDYDIVLDCTDNPATRYLISDTAVLLGKPLVSASALRTEGQLMVLNYPPRPVGDKSGGPCYRCVFPKPPPANSVVSCADGGILGPVVGTMGVLQALEAIKVITSPAVNPSASPPSLLIFSAYSTPLFRTIRLRARRANCAVCSADASVTLETLKNGSTDYVFFCGVAGLEATLSPEERISPLEFKKRHPKEVPQDGGRINKEPTIIDVREKVQFDICSLENSINIPISTILSSASSPTNVDANAQPSLPFWLPRELASADSTDPIYVVCRHGNDSQIAVRRLKELGLDRGGQRYVGDIQGGLRAWREQIDPDWPEY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a.  Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions (By similarity).
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase uba4, Common component for nitrate reductase and xanthine dehydrogenase protein F, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_RHILO
Sequence: MALDIKICGLKTDQAMAAALGGGASHVGFIFFAKSPRYVEPAEAGRLREAARGKAVAVAVTVDATDAFLDEIVSAMQPDMLQLHGSEHPERVAELKARYGLPVMKALPLSEAADLDRIRPFIGIADRFLFDAKPPKGSELPGGNGVAFDWRILAGLDAGVDYMLSGGLNAANIGDALRLANPPGIDISSGVESAPGVKDPALIEQFFRAVRAARDDRAA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: Y1525_CARHZ
Sequence: MAGHSKWANIKHRKEKMDSLRGKVFTKLAREIMVAARLGGGDPEANPRLKAAIARAREANIPNENIQRAIMKGTGELAAESYEEVFYEGYGPGGVAILLKIMTDNRNRTAGEIRHLFSKHGGSMGEAGSVQWIFEEKGYITIPKEDNPGINEEEILLLVLDAGAEDLKDEGDQFEVITAPEAFEKVKDALNNANIKTSIAEITMLPKTTVPVSGEEAQKLLKLLDLFEEHDDVQEVYANFELVD
What are the official names of this protein?
Probable transcriptional regulatory protein CHY_1525.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WFD12_PAPAN
Sequence: MGSSSFLVLTVSLALVTLVAAEGVKGGIEKAGVCPADNVRCFKSDPPQCHTDQDCLGARKCCYLHCGFKCVIPVKKLEEGGNKDEDVSGPCPEPGWEAKSPGSSSTGCPQK
What is the function of this protein?
Antibacterial protein.  Putative acid-stable proteinase inhibitor (By similarity).
What are the official names of this protein?
WAP four-disulfide core domain protein 12.
What are the subcellular locations of this protein?
Secreted.
Protein: IE2_NPVAC
Sequence: MSRQINAATPSSSRRHRLSLSRRRINFTTSPEAQPSSSSRSQPSSSSRSHRRQERRQEQRVSEENVQIIGNVNEPLTRTYHRQGVTYYVHGQVNISNDDPLLSQEDDVILINSENVDRERFPDITAQQYQDNIASETAAQRALQRGLDLEAQLMNEIAPRSPTYSPSYSPNYVIPQSPDLFASPQSPQPQQQQQQQSEPEEEVEVSCNICFTTFKDTKNVNSSFVTSIHCNHAVCFKCYVKIIMDNSVYKCFCSATSSDCRVYNKHGYVEFMPINVTRNQDSIKQHWRELLENNTVNNHTTDLNYVEQLQKELSELRAKTSQVEHKMTMLNSDYIMLKHKHAVAELDLQKANYDLQESTKKSEELQSTVNNLQEQLRKQVAESQAKFSEFERSNSDLVSKLQTVMSRR
What is the function of this protein?
RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection.  Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral transcription and replication by targeting and ubiquitinating host proteins.  Acts as a transcriptional activator and activates a number of viral promoters including itself, IE1 and the promoter of 39K gene.
What are the official names of this protein?
E3 ubiquitin-protein ligase IE2, Immediate-early protein IE2, RING-type E3 ubiquitin transferase IE2.
What is the protein family that this protein belongs to?
Belongs to the alphabaculovirus IE2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: KDSB_CELJU
Sequence: MSFYVVIPARYASTRLPAKPLKDIAGKPMIQHVYERASQSQAKAVIIATDDARIQAVAQAFGAQVVMTSASHSSGTDRLQEVTRTLGLAADDIVVNVQGDEPLIPPAVINQVATNLAANTYASVATLSEPIHYLEDFHNPNIVKVVADKAGRALYFSRAPIPWPRDHFAKPDVNVLPDNFPAQRHIGIYSYRVALLDRFVTWPQATLESIESLEQLRVLANSEAIHVAEACAQVPGGVDTEADLQRVKALLEVGQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAD_SHISS
Sequence: MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHGNFHAQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGVVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGSTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP153_IXOPE
Sequence: MESFVAMKVVCITVLFVIVAVNESATSEANTSNAAKDTKKTNVTLQFPNYIPNPKQLALKLLEICKNNKSSLNSLTARSSTNYYAINDKYVDFKYYTFLCKHDKDRNVTLNMPPDTPCGPNGQKCANKSQCVGHIPGC
What is the function of this protein?
Salivary tick protein that downregulates host immune system by binding to both dendritic cells, and CD4(+) T cells.  Specifically binds to the CD4 coreceptor on T cells.  This interaction prevents the activation of the Src kinase, Lck, and its downstreamsubstrate Zap-70, and results in deficient activation of PLCgamma1, the repression of calcium fluxes triggered by T-cell antigen receptor (TCR) ligation, and a subsequent reduction in interleukin-2 production.  This salivary protein also binds to DC-SIGN (CD209) on dendritic cells (DC) and activates the Raf-1 kinase/MEK signaling pathway that results in down-regulating expression of pro-inflammatory cytokines.  Furthermore, it inhibits T cell proliferation induced by DCs (By similarity).  It also inhibits in vitro keratinocyte inflammation induced by Borrelia burgdorferi or by the major outer surface protein (OspC) of Borrelia.  In addition, it downregulates chemokines and monocyte chemoattractant protein 1, as well as several antimicrobial peptides such as defensins, cathelicidin, psoriasin, and RNase 7 (By similarity).  Apart from its immunomodulatory activities, it is also associated with protection of Borrelia spirochetes from antibody-mediated killing through its binding to OspC.  In vivo, tests on different immune disease animal models show promising therapeutic results, e. g. , in inhibiting HIV infection, experimental autoimmune encephalomyelitis, transplantation rejection, and asthma (By similarity).
What are the official names of this protein?
Salivary protein 15 Iper-3, Salp15 Iper-3, Salp15-like.
What is the protein family that this protein belongs to?
Belongs to the salp15 family.
Protein: ACSA_GEMAT
Sequence: MSDIDVLLQETRTFPPSEEFRAGAWVRDNALREAAAADPVGFWAKESEALDWMTPWSTALEWEPPRAKWFQGGTLNASVNCIDRHVHGPRRNKAALIWEGEPGDRRTFTYWDLYREVNLAANMLKKLGVGRGDRVAIYLPMIPEAVIAMLACARIGAIHTVVFGGFAPESLRDRINDCGCKLLITADGGSRRGQMVPLKRNADVALKECPSIENVLVVMRRRSGVGDETFAEMQEGRDHWWHRLKRQVPRYCEPEAMDAEDVLFVLYTSGTTGKPKGIVHTTGGFLTGVATTTKYTFDLKEEDVYWCTADIGWITGHSYLVYGPLANGATCVMYEGAPDWPDKDRFWQICERYGVTILYTAPTAIRAFMKWGTEYVKKHDLSQLRVLGSVGEPINPEAWMWYHEHIGDFQCPIVDTWWQTETGAIMITPLPGVTTTKPGSATVPFPGIRTALLDANANELTVGGGLLAITHPWPSMLRTIWGDDQRYVDTYFSKWPGRPDLYFPGDGAKLDEDGYLWILGRVDDVLNVSGHRIGTMEVESALVDHPSVAEAAVVGKHHDLKGQAIAAFVTLRAGFTASGSLRDELRDHVAQKIGALARPDDILFSADLPKTRSGKIMRRLLRDIAEGRALGDTTTLADPSVVASLKDQYEAQES
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: LEPA_STRZP
Sequence: MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYS_HAHCH
Sequence: MLDPKLLRNSLDEVAARLKTKRYDLDVDAFSQLEERRKSVQVRTEELQSERNSKSKNIGMMIKQGQDPQPLKDEVAKIGEQLETAKAELQDIQDKLDDLLQGIPNLPDASVPEGASEDDNVEVRQWGSVREFDFEPKDHVDLGESLGLLDFNSGAKLAGSRFVVMRRELARLHRALAQFMLDIHTTEHGYQETMTPFLVHAHALQGTGQLPKFEADLFKVPGEHDFYLIPTAEVPVTNLVREEILDAKELPLKMTSHTPCFRSEAGSYGRDVRGMIRQHQFEKVELIHVVAPEQSDAALEELTGNAERILQLLNLPYRVVALCGGDLGFSAAKTYDIEVWLPAQKKYREISSCSNCRDFQARRMQARWRNPETGKPELVHTLNGSGLAIGRTLIAVLENYQQADGSILVPDVLEPYMGGVKVIKSAN
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM14_RECAM
Sequence: MIQVETMLKVADNSGAKRVQCIKVLGGSKRRYGSVGDTIVVAVKECMPRKKVKKGDVKKAIIVRTKKPIYRKDGSTISFENNAVVLINEQGIPIGTRILGPVTKELRKKKLVRIVSLASNVL
What are the official names of this protein?
60S ribosomal protein L14, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOZ_METNO
Sequence: MARVTVEDCIDKVENRFELVLLAGHRARLLSSGAPLTVDRDRDKNPVVALREIADQTITPDDLKEQLIHSLQKYVEVDEPEAEAVPLLSSSPAAAAVAPQSSGDDGDIQFDRMSEEDLLRGLENLAPPTETEDEGD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PSBB_TRICV
Sequence: MALPWYRVHTVVLNDPGRLIAVHLMHTALVAGWAGSMALYELAVFDPSDPVLNPMWRQGMFVMPFMTRLGITDSWGGWSITGESVSNPGIWSFEGVALSHIILSGMCFLAAIWHWVYWDLELFRDPRTGEPALDLPKIFGIHLFLSGLLCFGFGAFHVTGLFGPGIWVSDAYGVTGKVQPVAPAWGADGFNPFNPGGIAAHHIAAGIFGIFAGIFHLTVRPPQRLYRALRMGNIETVLSSSIAAVFFAAFVTSGTMWYGAAATPIELFGPTRYQWDSGYFQQEIERQVETSVSEGLSESQAWSRIPDKLAFYDYIGNNPAKGGLFRAGPMNKGDGIAEAWLGHPIFRDKDGRELTVRRMPAFFETFPVILVDKDGIIRADIPFRRAESKYSIEQVGVTVDFYGGKLNGQTFKDAPTVKKFARKAQLGEVFEFDRTSLESDGVFRSSPRGWYTFGHANFALLFFFGHLWHGGRTIFRDVFTGIGAEVTEQVEFGAFQKLGDKSTKKQGAV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: OTC_MYCLE
Sequence: MTRHFLRDDDLSPTEQADILALAADLKKAPFSRRPLAGPRGVAVIFDKNSTRTRFSFDIGIAQLGGHAVVVDGLSTQLGRDETLQDTARVLSGYVDAIVWRTFGQHRLDAMAATATVPVVNALSDEFHPCQVLADLQTIAERKGSLNGLRLSYFGDGANNMAHSLMLGAVTAGVHVTVATPVGFTPDPSVLAAAKKRAEATGASVTVTVDADTAAAGADVLVTDTWTSMGQENDGLDRVKPFWPFQVNARLVGLADSEAIVLHCLPAHRGDEITNEVMDGPTSAIWDEAENRLHAQKALLVWLLER
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_LIMF3
Sequence: MRLLGLDVGSKTVGVAESDPLGWTAQAVEIIPIDEEAEVFGLERVAELVKSRQVAGFVLGLPKNMNNTEGPRVEAARHYGELLEERFGLPIDYQDERLTTVQAHRMLVEEADVSRRKQKKVIDELAATLILQNYLDCHGKLCAKL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNX_BACCZ
Sequence: MKIEAVIFDWAGTTVDYGCFAPLEVFMEIFHKRGVGITAEEARKPMGLLKIDHVRALTEMPRIANEWNRIFGKLPTETDIQEMYEEFEEILFAILPRYASPIHGVKEVIASLRERGIKIGSTTGYTREMMDIVAKEAALQGYKPDFLVTPDDVPAGRPYPWMCYKNAMELGVYPMNHMIKIGDTVSDMKEGRNAGMWTVGVILGSSELGLSEEEVENMDPAELREKIEVVRNRFVENGAHFTIETMQELESVMERIEKQELIIS
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: ETFA_MOUSE
Sequence: MFRAAAPGQLRRAASLLRFQSTLVIAEHANDSLAPITLNTITAAGRLGGEVSCLVAGTKCDKVVQDLCKVAGVAKVLVAQHDAYKGLLPEELTPLILETQKQFSYTHICAGASAFGKNLLPRVAAKLNVAPVSDIIEIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFEAAATSGGSASSEKAPSSSSVGISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK
What is the function of this protein?
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).  Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism.
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PHLC_LISIV
Sequence: MEKFKIIKTIPKICGAFIFLLFFTFLFGHYGELKTQASDEYPGNFKITSHNVYLFSRNIYPNWGQMHRADLIAQADYMKNNDVVILNEAFDTSASHRLLNNLREMYPHQTPVIGRSKHGWDKTEGNYSNFALEDGGVAVVSQWPIVEKSQHIFQRGGGADRLSNKGFAYVKIMKNGKPYHIIGTHTPADDSLISKDTSRAIRAEQMQEIQTFIAKKNIPKDEIIFIGGDLNVNYGTDEYHDMFKLLNVSSPANFNGQMATWDPTTNSMLKESYPKAAPEYLDYIFVENGHARPHSWHNKVLHTKSPQWSVKSWFKTYTYQDFSDHYPVVGFTDNN
What is the function of this protein?
Virulence factor that promotes intracellular proliferation by mediating the disruption of the phagocytic vacuole and the release of bacteria into the host cell cytosol.  May act in concert with the phospholipases PlcA and PlcB and the hemolysin hly to mediate efficient escape from the vacuole.
What are the official names of this protein?
Sphingomyelinase C, SMase, Sphingomyelin phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the neutral sphingomyelinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: LUXS_SALG2
Sequence: MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: UL79_HHV6U
Sequence: MTQIGQYIKLNDAVPNLILHITTKLLRNENLTSFKQEELLLIQHVCTSMLSHGIKILLLRESLYNSGIGDIVILNRKISNNYWFRIFSILKQHSDAELLRHMFNESHSAYISKKLHYSGNVSHMINFLFMDEFGVNLKIPEELICEGNIVFSVGAIYNHRLLKICRFFNRFWGDQEREPTVRLICKHLWFAYLIMFGKFEISTLAYSQQRAEHKAGLFSFLQNDFKVFCGMSENPQLLDSSAIFDLTGISAEDLFSYE
What are the official names of this protein?
Protein U52.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL79 family.
Protein: RLME_PSET1
Sequence: MTNKKQSASSQRWLKEHFDDKYVQEAQKKGWRSRAVFKLDEVQSRDKLLRPAMTVVDLGAAPGSWSQYLAEKVGDKGQVIACDILPMDSLAGVDFLQGDFREEAVLSALLKRIDGKNVDVVLSDMAPNMSGNNSVDQAGSMYLVELALDMCNQVLKKNGAFIVKVFQGEGFDQFLQDVRNSFKTVKIRKPDASRARSREVYIVATGYKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.