PharMolix/UniProtQA huggingface dataset:
Protein: ARCA_BORRA
Sequence: MQYLKPINVFSEIGRLKKVLLHRPGKELENLTPSIMKRLLFDDIPYLHVAIQEHDSFADTLRGNGVKVVYIEDLISETLSNDDSIKEQFISQFILEAGIRTENKTRALKDYFCNMSVNDMISNMIAGVTRDDLKNYKSDSLNSLVNSEYPLIIDPMPNILFTRDPFASIGHGVTINRMSTKTRHRETIFAEYIFKYHPIYKDNVPIWYNRDEDTTLEGGDELVLSRDVLAIGVSERTESESVEKVARKLFEQKISFNTILAFQIPQSRAYMHLDTVFTQIDHTTFTSFISDDMKFTIYALTYDVSSGSIKVKSEKAKLEDILGFYFGCKVNIIKCAGGDLIHGAREQWNDGANTLAISPGEVIVYSRNHMTNKLLEEFGIKVYQIPSSELSRGRGGPRCMSMPLIREDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_LEPCP
Sequence: MNFIDQLARAERLHDSLLCVGLDPEPGKFPGAWKGDAGKIFDFCAAIVDATKDLVIAFKPQIAYFAAHRAEDQLERLMAYIKRTAPDVPVILDAKRGDIGSTAEQYAREAFERYQADAVTLSPFMGFDSIEPYLRYADKGVILLCRTSNPGGNDWQMQRLADVPGQPRLFEHLAHRAQTEWNRNGQLALVVGATYPAEIARVRELAPTLPLLIPGVGAQGGDAQATVQAGLVCDASGASTGPIIVNSSRAVLYASAGDDFAQAARRVALATRDALNAASAAARR
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: SECF_TREPA
Sequence: MRQVVRFSLLFLPCAILSVVLIGAGVLRWALWGMSFGIDFQSGLIERLRIAPPAFSLVYTGTQSMQFFQDEQKVVFTVSSPGVLGERYEFLYTEYPTLRAFSEGAKKVEHLSVTLHAPETVYMRDTFSGAEGSTLSSASCFVHYFSEDVRAPGVEELRRVLKDVPSAVVQQVGVRAEHTFQVRVAAETAFPSSLLPEQGGTALAQSDAPDLVTPQGAVESVVYAALVRAYGADHVVRLAMDFVGSRFSHLLVRQALLLVLGALVLIFLYVALRFRWFFALGAIVALVHDACIMVSFMVWFGLEFNSASIAAILTIIGYSINDTVVVFDRVRQTILLDPIASVTTVLDRSQTDMLTRTVVTTVTTLLAALMLYVFTEGGSRDFSLALMVGMVSGVYSTIYIAGGCIALISRGKSGGQLLGL
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDHM_CITLA
Sequence: MKASILRSVRSAVSRSSSSNRLLSRSFATESVPERKVAVLGAAGGIGQPLALLMKLNPLVSKLALYDIAGTPGVAADVGHVNTRSEVTGYVGEEQLGKALEGSDVVIIPAGVPRKPGMTRDDLFNINAGIVKSLCTAIAKYCPNALINMISNPVNSTVPIAAEVFKKAGTYDEKKLFGVTTLDVVRAKTFYAGKANVPVAEVNVPVIGGHAGITILPLFSQATPRANLSDDTIVALTKRTQDGGTEVVEAKAGKGSATLSMAYAGALFADACLKGLNGVPDVVECSFVQSTVTELPFFASKVKLGKNGVESVLDLGPLSDFEKEGLEKLKPELKASIEKGIQFANAN
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PO3F3_MOUSE
Sequence: MATAASNPYLPGNSLLTAGSIVHSDAAGAGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGREDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSADTPPPHHGLQTSVQ
What is the function of this protein?
Transcription factor that acts synergistically with SOX11 and SOX4 (By similarity).  Plays a role in neuronal development.  Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3').
What are the official names of this protein?
POU domain, class 3, transcription factor 3, Brain-specific homeobox/POU domain protein 1, Brain-1, Brn-1, Octamer-binding protein 8, Oct-8, Octamer-binding transcription factor 8, OTF-8.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
Protein: RL3_SACD2
Sequence: MTIGIVGRKSGMTRIFTDDGLSVPVTVVEVDPNRITQVKSVETDGYAAVQVTVGSRRASRVSKPEAGHFAKAEVEAGRTVLELRNESGEQFEVGGLLTVEAFEAGQKVDVTGASKGKGFAGVIKRYNFRMQDATHGNSLSHRAPGSIGQCQTPGRVFKGKKMAGHMGAARVTTQNLEVVRVDVERNLLLIKGAVPGAPGGDVIIRPAVKSRNNG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RECG_MYCTO
Sequence: MASLSDRLDRVLGATAADALDEQFGMRTVDDLLRHYPRSYVEGAARVGIGDARPEAGEHITIVDVITDTYSFPMKKKPNRKCLRITVGGGRNKVTATFFNADYIMRDLTKHTKVMLSGEVGYYKGAMQLTHPAFLILDSPDGKNHGTRSLKSIADASKAISGELVVEEFERRFFPIYPASTKVQSWDIFKCVRQVLDVLDRVDDPLPAELRAKHGLIPEDEALRAIHLAESQSLRERARERLTFDEAVGLQWALVARRHGELSESGPSAAWKSNGLAAELLRRLPFELTAGQREVLDVLSDGLAANRPLNRLLQGEVGSGKTIVAVLAMLQMVDAGYQCALLAPTEVLAAQHLRSIRDVLGPLAMGGQLGGAENATRVALLTGSMTAGQKKQVRAEIASGQVGIVIGTHALLQEAVDFHNLGMVVVDEQHRFGVEQRDQLRAKAPAGITPHLLVMTATPIPRTVALTVYGDLETSTLRELPLGRQPIATNVIFVKDKPAWLDRAWRRIIEEAAAGRQAYVVAPRIDESDDTDVQGGVRPSATAEGLFSRLRSAELAELRLALMHGRLSADDKDAAMAAFRAGEVDVLVCTTVIEVGVDVPNATVMLVMDADRFGISQLHQLRGRIGRGEHPSVCLLASWVPPDTPAGQRLRAVAGTMDGFALADLDLKERKEGDVLGRNQSGKAITLRLLSLAEHEEYIVAARDFCIEAYKNPTDPALALMAARFTSTDRIEYLDKS
What is the function of this protein?
Critical role in recombination and DNA repair.  Helps process Holliday junction intermediates to mature products by catalyzing branch migration.  Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity.  Unwinds branched duplex DNA (Y-DNA) (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase RecG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.
Protein: RL11_RUTMC
Sequence: MAKKIESYIKLQVAAQEANPSPPVGPALGQHGVNIMEFCKAFNVKTQDIDKGMKVPVVITVYSDRSFTFVTKAPPAALLILKITGIKKGSGVPHLDKVGNITRIQLEEVASMKMKDLNANDMDAAVHIISGTARSMGITVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RR18_ADICA
Sequence: MNKSRHSSRRRSPSIRSDETIDYKNTSLLRRFVSEQGKILSRRMNRLTSKQQRLIATAIKRARILALLPFSNNES
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HBAD_DRYME
Sequence: VLTAEDRRLLQASVGKLGCRLEDIGADALNRLLIVFPQSKTYFSHFNLSPGSKDIVHQGEKVGKALDSALKHLDDIRGTLSQLSDLHAYNLRVDPVNFQLLSKCLHVSLATHLRNEYNASTCLAWDKFLEQVADVLCEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: UBID_BURMA
Sequence: MKYRDLRDFIHGLEQRGELRRVTQPVSPVLEMTELCDRVLRAGGPALLFDAPAGHRFPVLGNLFGTPRRVALGMGVDADDEAALASLRDIGRLLSALKEPDPPKRLKDAGKLLSLAKAVWDMGPKTVSAPPCQEIVWEGDDVDLHKLPIQTCWPGDAGPLLTWGLTVTRGPNKTRQNLGIYRQQLIGRNKLIMRWLAHRGGALDFREFALKHPGQPYPVAVVLGADPATMLGAVTPVPDSLSEYQFAGLLRGARTELAKCVTPGVDALQVPARAEIVLEGFIHPQQGAPAPAPEGAPPRPAAGAAAGYEHALEGPYGDHTGYYNEQEWFPVFTVERITMRRDAIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFAEITDFYLPPEGCSYRMAIVQMKKSYAGHAKRVMFGVWSFLRQFMYTKFIVVVDEDVNVRDWKEVIWAITTRVDPARDTVLVENTPIDYLDFASPVAGLGSKMGLDATNKWPGETQREWGRPIEMDAAVKARVDRLWTEIGLS
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TARI_STRZP
Sequence: MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEPSIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPLTPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPNRAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLKITTVTDLKIAKSMIEKD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: RSMA_SYNS9
Sequence: MSFSGHTARKRFGQHWLRDARVLDQIVEAARLQQDDCVLEVGPGRGALTERLLASPAAQIHAIELDRDLVRGLHDRFGSESRFSLREGDVLEAPLHLVDGGFANKVVANIPYNITGPLLARLIGRLDRPVEPTYDCLVLLLQKEVAERIRAKPGRSSFSALSVRMQLLADCSLVCPVPPRCFQPPPKVQSEVILLKPFPPERRLPIDLASRVEALLKQAFQARRKMLRNTLAGVIDPQVLEPLAASVGISLQQRPQEVAAEAWVALARGLNQDV
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZGPAT_DROGR
Sequence: MDEYEAQLLVVEQALLVTTDEQQREELSALRTNLEELLALTRSSETEATNNISTAQTNGDLDDELKRFQSELNDLKEQEQEETDTTDDKQQLEELRAKYNALLGEKCSAPHEHSWGALSYHNALICGVDDELIIDGNGILDVRLRVLFTNPTHREMLPCNYYLEGECRFDEIRCRFSHGALVPGASIKEYNAPDFHKLARNCPVLAKLQDRLWHRGRVLCVNFVEQQCRVRLDGQEHKERERDFPFEELFPLIADEDDELSSDSSESHSTEDSDAANDSDMDDLEAARQARMVELSLFTFKPTEKLGAWEQYTRGIGSKLMANMGYIHGTGLGSDGRGIVTPVSAQILPQGRSLDACMELREAANGDKNYFSVERKLKRAQRRQQAANEKAYARESKRTDVFAFLNGSVLGQAQNSTKTTKTSNLQQHSNKTLNVETVRIADDIRRKQRDIAKVQQSLARNATDAQLQKRLNGQLRAHQQELATLQAQESSLSKEQQTRKSKNKMFAF
What is the function of this protein?
Transcription repressor.
What are the official names of this protein?
Zinc finger CCCH-type with G patch domain-containing protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS4_LISW6
Sequence: MQIFPAIDLKNGQCVRLFQGDFSKKMIVNEDPIAQAKAFATGGATYLHIVDLDGALEGRPVNLEIIQKMKEAATVPVQVGGGIRSLAQVDYYLDSGIDRVIIGSAALTNPDFLHAAVQKYGPKIAVGIDAKNGYVATSGWLEVSQVNYLDLAKQMEKVGVETIIYTDISRDGTLTGPNLEQMAALQKHVNIHLIASGGVSSRADLEALSQLGLYGAIAGKALYNGHISMSDVTEVENHAY
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y508_THEMA
Sequence: MSISEKPLSELLRPKDFEDFVGQDHIFGNKGILRRTLKTGNMFSSILYGPPGSGKTSVFSLLKRYFNGEVVYLSSTVHGVSEIKNVLKRGEQLRKYGKKLLLFLDEIHRLNKNQQMVLVSHVERGDIVLVATTTENPSFVIVPALLSRCRILYFKKLSDEDLMKILKKATEVLNIDLEESVEKAIVRHSEGDARKLLNTLEIVHQAFKNKRVTLEDLETLLGNVSGYTKESHYDFASAFIKSMRGSDPNAAVYYLVKMIEMGEDPRFIARRMIIFASEDVGLADPNALHIAVSTSIAVEHVGLPECLMNLVECAVYLSLAPKSNSVYLAMKKVQELPVEDVPLFLRNPVTEEMKKRGYGEGYLYPHDFGGFVKTNYLPEKLKNEVIFQPKRVGFEEELFERLRKLWPEKYGGESMAEVRKELEYKGKKIRIVKGDITREEVDAIVNAANEYLKHGGGVAGAIVRAGGSVIQEESDRIVQERGRVPTGEAVVTSAGKLKAKYVIHTVGPVWRGGSHGEDELLYKAVYNALLRAHELKLKSISMPAISTGIFGFPKERAVGIFSKAIRDFIDQHPDTTLEEIRICNIDEETTKIFEEKFSV
What are the official names of this protein?
Uncharacterized protein TM_0508.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
Protein: Y1861_STAA3
Sequence: MAMTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHE
What are the official names of this protein?
UPF0435 protein SAUSA300_1861.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: RR12_MORIN
Sequence: MPTIKQLIRNTRQPIKNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATP5E_RAT
Sequence: MVAYWRQAGLSYIRFSQICAKAVRDALKTEFKANAEKTSGTSIKTVKIKKE
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element.  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit epsilon, mitochondrial, ATPase subunit epsilon, ATP synthase F1 subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase epsilon family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: ERYBV_SACER
Sequence: MRVLLTSFAHRTHFQGLVPLAWALRTAGHDVRVAAQPALTDAVIGAGLTAVPVGSDHRLFDIVPEVAAQVHRYSFYLDFYHREQELHSWEFLLGMQEATSRWVYPVVNNDSFVAELVDFARDWRPDLVLWEPFTFAGAVAARACGAAHARLLWGSDLTGYFRGRFQAQRLRRPPEDRPDPLGTWLTEVAGRFGVEFGEDLAVGQWSVDQLPPSFRLDTGMETVVARTLPYNGASVVPDWLKKGSATRRICITGGFSGLGLAADADQFARTLAQLARFDGEIVVTGSGPDTSAVPDNIRLVDFVPMGVLLQNCAAIIHHGGAGTWATALHHGIPQISVAHEWDCMLRGQQTAELGAGIYLRPDEVDADSLASALTQVVEDPTYTENAVKLREEALSDPTPQEIVPRLEELTRRHAG
What is the function of this protein?
Involved in the biosynthesis of the macrolide antibiotic erythromycin.  Catalyzes the reversible transfer of mycarosyl from dTDP-beta-L-mycarose to erythronolide B to yield 3-alpha-L-mycarosylerythronolide B.  It can also use TDP-beta-L-cladinose.
What are the official names of this protein?
Erythronolide mycarosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
Protein: PROA_SULNB
Sequence: MEAFLEEAKASSRVLAGISGADKNRILKEMAQALRASTAEILKANALDMEDADRNDLTPALKDRLLLDESRVEGMAVAVEEIAALKEPVGRVLDGWVTEDGLKIEKVSVPIGVIGIIYESRPNVTSDTAALSFKSSNVCVLKGGKEAQHSNEAIAKVLRAVLKKNGLPEALISLIPDASREGVAKLIKMDKYVDLIVPRGGEGLIRYVSENASVPVVKHDKGQCHTYIDEDANVENAIRIAINAKVQRPGVCNAMETLLVDTAIAKEVLPLLKEAFDAAHTELKGCGETQEIIEVAPATEVDFDTEYLANILNIRVVDGVEGAIDHIVRYGSGHSEAIITENITTAEAFLNGIDAAVVYVNASTRFTDGGAFGFGAEVGISTNKLHARGPMGIEGLTTYKFKIYGSGQIR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPRE2_MYCTO
Sequence: MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRREDAAAAMKQAGARSVELIDFDALDTDSHPKMIEAAFSGGDVDVAIVAFGLLGDAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAGERVRRANFVYGSTKAGLDGFYLGLSEALREYGVRVLVIRPGQVRTRMSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMVLRHIPRSIFRKLPI
What is the function of this protein?
Component of the DprE1-DprE2 complex that catalyzes the 2-step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl-phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans.  DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX).  The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'substrate channel' at the interface of DprE1-DprE2 complex.  DprE2 then catalyzes the second step of epimerization, the NAD(+)-dependent reduction of DPX that leads to the formation of DPA.
What are the official names of this protein?
Decaprenylphosphoryl-2-keto-beta-D-erythro-pentose reductase, Decaprenyl-phospho-2'-keto-D-arabinose reductase, Decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase, Decaprenylphosphoryl-beta-D-ribofuranose 2'-epimerase subunit DprE2, Decaprenyl-phosphoribose 2'-epimerase subunit 2, NAD-dependent decaprenylphosphoryl-D-2-keto-erythropentose reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ISPE_SHEHH
Sequence: MTAPLSLGWPAPAKLNLFLHINARRHDGYHELQTLFQFVEHCDYLDFKVLDKPELKLHSNLAGVVADSDNLILKAAKSLQQHTKCQFGVEIWLDKRLPMGGGLGGGSSDAATTLVALNQLWETGLSATELCELGLKLGADVPVFINGFSAFAEGVGEKLQNVEPAEPWYLVLVPQVHVSTAEVFQDPELPRNTPKLSLESLMNSPWQNDCQSLVAKRHPQVAKTLGWLLEYAPSRMTGTGACVFGQFEQEQEAKDVLAKLPASIQGFVAKGANISPLMLRLAQC
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RUVA_LIMRD
Sequence: MYEYLTGLVTVVAPQYIVVDVNGVGYKLLVANPYRYQEDRTKKVQVYVYQAVREDNISLFGFTDQNEKNLFMQLINVSGIGPKSALAILANPDHQGLVDAITNNNVSYLTKFPGIGKKTASQIVLDLRDKLTNESSSSLFATTQLTVDATVNRELKDALEALAALGYKERDIKKVQKALMKEEQMATDEYLRQALRLLN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: KNOX1_MAIZE
Sequence: VRQELKLELKQGFKSRIEDVREEILRKRRAGKLPGDTTSILKQWWQEHSKWPYPTEDDKAKLVEETGLQLKQINNWFINQRKRNWHNN
What are the official names of this protein?
Homeobox protein knotted-1-like 1.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACP_PHOV8
Sequence: MSEIASRVKAIIVDKLGVEESEVTTEASFTNDLGADSLDTVELIMEFEKEFGISIPDDQAEKIGTVGDAVSYIEANAK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_THESQ
Sequence: MARLRVYELARKLNMSPKELLQELEELGVNVKSHMSYVDEEMANIIIDLLEEDNRKAKQPSKPKKEKGEEEVEKEVVEKKKKKKITLKPDELKLDIIAEKIGVPQNKIIQDMFVKRGIALRPGQILKLEEVEQILKEYKIEIEIEEEQQTSVEEVDEFELLEKRYQELYEKEKDKLVPRPPVVTVMGHVDHGKTTLLDRIRSTRVAEREEGGITQSIGAYQVEVNGKKITFIDTPGHELFTEMRARGAQATDIVVLVVAADDGVMPQTIEAYNHAKAANVPIIVAINKIDKPNANVEKTKQELVEKLGLIPEEWGGDTIVVPISARTGQGVDELLEMILLVAEMNEIKCYPEGPARAVIIESKLDKKMGPVASVIVKDGVLKVGDAVVASNTYGKVRNLFDDNMRPIREAYPSQPVMILGFEDVPDVHSNVYVVESVEKAKEIVEKRLQRLEAQKQSRKHINLEDLMKMMQEKEKKVLNLILKADTYGSVAALKNAINKLQSKEIELNIVHAGVGEISTSDVMLAAAVDGVILGFRVKVNNQARRLAEQEGVDVRTYSIIYKLVEDLKLALEGMLEPEEVEEVIGHGEIRKVFKISKVGKVAGVQMLDGKADRNGFVRIYRNGQLVFEGKIESLKHYKEDVNVVEAPQECGIKFAGFDDIQEGDELEFYVIRKVKRKPTFVEEQSDQEQK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORN_SHEB5
Sequence: MTADVNNLIWIDLEMTGLEPDVDRIIEIATLVTDQELNIIGQGPVIAIHQSDDVLAAMDDWNQKHHGESGLIDRVRASQETEAQAVAKTIAFLEQYVPKGASPMCGNSIGQDRRFLNRYMRELEDYFHYRNVDVSTIKELVKRWSPETMAGFKKQNTHQALQDIQESIAELQYYRSKVFKI
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_CLOK5
Sequence: MELLVKRINKEAILPFYAHEGDAGLDLFSVEEVLIKPMERKLIATGIKIQLPPNTEGQVRPRSGLALAHGITLLNSPGTIDEGYRGEIKVLMINLGQEGFLIKKGMKIAQMVIKPIEQVLIKEVVELKDTERGEGGFGSTGTM
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RS15_DESPS
Sequence: MAQSAVVKNEIIEKFKTHEGDTGSSEVQIALLTDRIQYLTDHFKTHKKDHHSRQGLLKLVGQRRSLLDYLKKKNVTTYRELIKALGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y1384_METJA
Sequence: MGDTMEIQLPDIEEIKLEDVLIKRRSVREYCSSPLTLRELSHILFAAYGVTDERGFKTVPSAGATYPLEIYVNVRDVVGVEEGVYKYIPERHSIVRILDEEVGHELALAALKQMFIAIAPIVLIIAANYERTTRVYGDRGFRYVHMEVGHVAQNVYLMATSLGLGTVSVGAFYDNEIREILKIKEYPLLLMPVGRKIE
What are the official names of this protein?
Putative nitroreductase MJ1384.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.