PharMolix/UniProtQA huggingface dataset:
Protein: FADB_YERPA
Sequence: MLYQSETLQLHWLENGIAELVFDAPGSVNKLDTKTVANLGEALNVLEKQSELKGLLLRSAKTALIVGADITEFLSLFNAPPEKLHQWLVFANTIFNRLEDLPVPTISAINGYALGGGCECILATDFRIASPEARIGLPETKLGIMPGFGGSVRLPRLLGADSALEIIATGKDVTANDALKIGLVDAVVDPEKLVGSALTMLKQAIDGKLDWQAARRPKLEPLKLNPTEAAMCFTIAKGRVMQVAGKHYPAPLTAVKTIEAAAKFGRTEALNLETNSFVPLAGSNEARALVGIFLNDQYVKAQAKKLSKGVAAPKLAAVLGAGIMGGGIAYQSALKSVPVIMKDINENSLDLGMNEAAKLLNKQLERGKVDGLKMASILATIRPTLDYAGIERAQVIVEAVVENPKVKAAVLAEVEALIGEDTVLASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGAKTSDKTLAAVVAYATQMGKTPIVVNDCPGFFVNRVLFPYLAGFGMLVRDGGDFHQIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPERMNKDYRDAVDVMFDNQRFGQKNGQGFYRYTQDAKGKPRKENDEQVDKLLAEISQPLQEFSDEDIIARTMIPMINEVVRCLEEGIIASAAEGDMALVYGLGFPPFHGGVFRYLDTLGSANYVEMAQRYAHLGALYHVPAGLRAKAEHNESYYPVAAALLDVSTNQPA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: GCSP_SHEFN
Sequence: MTKQTLTQLEQHELFLTRHIGPNAEQQQEMLNFIGAESLEDLTAQTVPGKIRLPQDLTIGDSCGEAEGIAYIRNIADKNKVFKSYIGMGYYGVQVPNVILRNVFENPGWYTAYTPYQPEIAQGRLEAILNFQQVSMDLTGLDLASASLLDEATAAAEAMALAKRVSKAKKANIFFVADDVFPQTLDVVKTRAECFGFEVVVGPASEAVNYELFGALFQYTNRIGQITDYTELFATLRDNKVIVTVAADIMSLMLLKSPGAMGADVVFGSAQRFGVPMGYGGPHAAFFVARDEHKRSMPGRIIGVSKDTRGNSALRMAMQTREQHIRREKANSNICTAQILLANMASFYAVFHGPQGLKTIASRINRLADILAAGLTAKGLTLANTTWFDTISVKGADVAAINARAIAAQVNLRIDADGVFGISLDETTIRTDIADLFDVILGAGHGLDVATFDADIVANGSQSIPDALVRQDAVLTHPTFNRYQSETEMMRYIKRLENKDLALNHSMISLGSCTMKLNAAVEMLPVSWPEFANMHPFCPLDQAQGYTQLINELSEFLVKITGYDSVCIQPNSGAQGEYAGLLAIKKYHESRGDAHRNICLIPQSAHGTNPASAQLAGMKVVVTACDKQGNVDLEDLRTKAAELADSLSCIMITYPSTHGVYEESIREVCEIVHQYGGQVYLDGANMNAQVGLTSPGFIGADVSHLNLHKTFAIPHGGGGPGMGPIGVKSHLAPFVAGHTVIKPGRESDHNGAVSAAPYGSASILPISWMYIKLLGTKGVKQSTQTALLNANYIMKKLSAHYPVLFTGRNDRVAHECIIDLRPLKETSGVTEMDIAKRLNDYGFHSPTMSFPVAGTLMIEPTESESKVELDRFIEAMISIRGEITKVEAGEWPVDNNPLHNAPHTLADIMDPEFDSRPYSREVAVFPTAAVKANKFWPTVNRIDDVYGDRNLMCSCVPLSDYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: Y1118_PICTO
Sequence: MEIIWHGHACFSINGRKNVLIDPFLAGNPLSKIKPEDIDADIILLTHGHFDHAGDAVNIAQRLKIPVLAAFELTELLKKDVKTIDINQGGTVDFDDIKIKAVNAIHSSSYNGMYAGNPLGFIVTDERMYYHAGDTQYFSDMELISKYDKPEIVMLPIGGHYTMDVNEALIALDILRPKIAIPMHYNTFPVIKADPQDLKKEASKLGIEVIIPEIEEKIDL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase PTO1118.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: RSMH_PSEPF
Sequence: MTIDSGFNHITVLLDEAVEALAVRPDGCYLDGTFGRGGHSRLILSKLGPDGRLIGFDKDPQAIATGQTLAAEDGRFVVVQRSFAELGSVVAERGLTGKVSGILLDLGVSSPQLDDAERGFSFLNDGPLDMRMDPSRGISAAEFVNTAPVEEIARVFKEYGEERFSGRMARAVVERRDVTPFERTADLAEVLKVANPAWEKGKNPATRAFQGLRIQVNNELGDLEAGLEAALECLEVGGRLVVISFHSLEDRIVKLFMRKLVKGEADNLPRNLPVRHVAFEPKIKVHGKAQTASDAELKANPRSRSAVMRVAEKLR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_STAAT
Sequence: MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDKVTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQDIVDDYKNKILDAMEANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: PYRE_BRADU
Sequence: MSKSASRARLFEIIRRRSFGRGEVTLASGRKSDFYFNLKPTMLDPEGATLLAELTYEALKDDNLDFIGGLEMGAVPLAGALAQISWIKGHPIAAFFVRKKPKEHGAKLAIEGLPRGETLQGKRVVIVEDVTTTGGSAMKAVESVRETGAEVVLVLTMVDREEGATDTFGAAGLPFRSLYKASEFLKA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RPOA2_FRATO
Sequence: MALENLLHPTNIKIDEYAKNATKFSFEALERGVGYTLGFALKQTMLYSIAGACVTSIKINDGKVTSLEDVIPCDETVADIILNVKSLSVTLAEDVETGTITFELSGSEEEIFSEEAKLSEGLAITEEVFICSYNGGKKLKIEAKVEKGVGFRPAQDNFKDGEFLLDATFSPVVFCDFEIKDARVGRRTDLDKLELNIKTNGNVNCEEALRLAATKIQNQLRNIVDIEEINKGIFVEDPKDINPILLKHVEELNLTARSSNCLKAVNIRLIGELVQKTENELLKAPNFGKKSLTEIKDKLSELGLSLGTLIENWPQDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha 2, RNAP subunit alpha 2, RNA polymerase subunit alpha 2, Transcriptase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: FAPR_THEPX
Sequence: MAVRMSKVERQRLLKEKINTNPFYTDDELAEMFGVSVQTIRLDRMELGIPEVRERIKSVAEENYQKVRTITGTEVVGELIDLELGKRGISIFEPTEDMVFVKTKIVKGQYIYSQAESLAMSVIDASAALIGVANIKYKFPVKVGDRLVAKAEVIRQRGNKYFVWVKIKVKDKEVFRGKFILVAIDEDFLKKRSDTVEVSN
What is the function of this protein?
Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
What are the official names of this protein?
Transcription factor FapR, Fatty acid and phospholipid biosynthesis regulator.
What is the protein family that this protein belongs to?
Belongs to the FapR family.
Protein: HELS_AERPE
Sequence: MSKGLYDIPSWATTETRTLAKLAGVERLFEPQYMALQAGVEKGENLVVAAPTGSGKTFIALVAIVNSLARAGGRAFYLVPLKSVAYEKYTSFSILSRMGLKLKISVGDFREGPPEAPVVIATYEKFDSLLRVSPSLARNVSVLIVDEIHSVSDPKRGPILESIVSRMLASAGEAQLVGLSATVPNAGEIAEWIGGKIVESSWRPVPLREYVFKEYKLYSPTGGLREVPRVYGLYDLDLAAEAIEDGGQALVFTYSRRRAVTLAKRAAKRLGRRLSSREARVYSAEASRAEGAPRSVAEELASLIAAGIAYHHAGLPPSLRKTVEEAFRAGAVKVVYSTPTLAAGVNLPARRVVIDSYYRYEAGFREPIRVAEYKQMAGRAGRPGLDEFGEAIIVAERLDRPEDLISGYIRAPPERVESRLAGLRGLRHFILGIVAPEGEVSIGSIEKVSGLTLYSLQRGLPRETIARAVEDLSAWGLVEVKGWRIAATSLGREVAAVYLDPESVPVFREEVKHLSFDNEFDILYLISTMPDMVRLPATRREEERLLEAILDASPRMLSSVDWLGPEEMAAVKTAVVLKLWIDEASEDTIYGEWGVHTGDLLNMVSTAEWIASGLSRIAPYLGLNSKVSHILSVIARRIKHGVKPELLQLVEIPGVGRVRARILFEAGYRSIEDLATARAEDLMRLPLIGPSTARQILEFLGRVDEAREAEAREMLARKGLLSYLEGDAVAGEEGE
What is the function of this protein?
DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
What are the official names of this protein?
ATP-dependent DNA helicase Hel308.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Hel308 subfamily.
Protein: RS15_STRSV
Sequence: MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNDHIKRHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: LACC_STRZJ
Sequence: MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTRVLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVLEKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVVLDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWIIVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKANVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: FOLD_DESDA
Sequence: MLIIDGKKTAQDIRAELATEVTAATAEGRRAPGLAVILVGEDPASQVYVRNKEKACTEVGITSFAYRLPAETGQQELLDLIAECNARPDVDGILLQLPLPRGLDAQACLLAIDPAKDVDGFHPENVGRLSLGLPGFVSCTPAGVMELLRRYNLPTRGKKAVVVGRSDIVGKPLALLLTRSGEFGDATVTICHSRTPDLAEECRKADFLFLAVGRPRLITGDMVRQGAVVIDVGINRSDDGLCGDADYESVSKKAAAITPVPGGVGPMTIAMLLVNTVQSWRQRTA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ISPD_SHISS
Sequence: MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: TILS_METS4
Sequence: MSDAARPLDPDEAARRLGPWLGAGGQAGGVVLAVSGGPDSTALMGCAAALPPRVPVLVATVDHGLRPESGEEAAGVAALAGRLGLPHRILTWRGEKPRTRLQEAARAARYDLLLGLAREAGAGAILTAHTLDDQAETVLMRLCAGSGPAGLAGIAPARRLGGLLLGRPFLDLPKARLVATCAAAGWPFAVDPGNAAARFARARLRRVMPLLAAEGLTPARLARLAARLRRNEAALAAAAEAARPSLAAAPAGPGRLALDAAGLAALPEAVALRVLADAIAALRAGERRPERLERLEEALFGRILPAIAAGTPLRLTLGGALLDLAGGRLLLAPEPPRRRTKRAG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEGFA_COTJA
Sequence: MNFLLTWIHWGLAALLYLQSAELSKAAPALGDGERKPNEVIKFLEVYERSFCRTIETLVDIFQEYPDEVEYIFRPSCVPLMRCAGCCGDEGLECVPVDVYNVTMEIARIKPHQSQHIAHMSFLQHSKCDCRPKKDVKNKQEKKSKRGKGKGQKRKRKKGRYKPPSFHCEPCSERRKHLFVQDPQTCKCSCKFTDSRCKSRQLELNERTCRCEKPRR
What is the function of this protein?
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth.  Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.  Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity).
What are the official names of this protein?
Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family.
Protein: VNP_PHIOL
Sequence: MVASRLAAGGLLLLALLALALDGKPAPPQPLRKAPAGGTTAWRRELTEQPEGASRPAAGGGGGGGRSGSKAANAAPTAPKSKGGAAAAAAAAARLMRDLRPDSKQARAAWGRMVHPEHHAGGGGGGGGGGGASRRLKGVAKKGLGKGCFGLKLDRIGSMSGLGC
What is the function of this protein?
Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity.  Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3) (By similarity).
What are the official names of this protein?
C-type natriuretic peptide, CNP.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURE_FUSNN
Sequence: MNIFSGIEYKVLKDVNLDRKYDGIEYDSRKIKENYIFVAFEGANVDGHNYIDSAVKNGATCIIVSKKVEMKHNVSYILIDDIRHKLGYIASNFYEWPQRKLKIIGVTGTNGKTSSTYMIEKLMGDIPITRIGTIEYKIGDKVFEAVNTTPESLDLIKIFDKTLKKKIEYVIMEVSSHSLEIGRVEVLDFDYALFTNLTQDHLDYHLTMENYFQAKRKLFLKLKDINNSVINVDDEYGKRLYDEFIVDNPEIISYGIENGDLEGDYSDDGYIDVKYKNQIEKVKFSLLGDFNLYNTLGAIGIALKIGISMEEILKRVSNIKAAPGRFEALDCGQDYKVIVDYAHTPDALVNVIVAARNIKNGSRIITIFGCGGDRDRTKRPIMAKVAEDLSDVVILTSDNPRTESPEQIFDDVKKGFIKSDDYFFEPDREKAIKLAINMAEKNDIILITGKGHETYHIIGTKKWHFDDKEIARREIVRRKMVENVN
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_METMJ
Sequence: MRSDQIRQGRLAGERSGDLEHFLASMDADRWIARADLLVDMAHLLGLSRQGIIDEAPARALMAALLDLYDHGVPEEAFDERFEDVHAGKEAYLIDRVGEDFGGRLHMGRSRNDEVATCIRIRLKEEIIALLRSLVDLRATLLDVAAGHTGTVMPGFTHLQHAQPTTLAHYLLAYEQAFSRDTARLREAYARVDVSPLGSAAFASTGFPLDRAYTASLLGFSRPAGNSMDAVAARDFAIEVLADASICMTSTSRLCEELVLWSTAFVGFVRLDDAYCSSSSIMPQKKNPDVAEIMRAKAGSVAGSLAAAITITKGLPMSYNRDLQELTPHLWRGVEAARQSIPLLSGMLGSATFDAERMAAEAGRGFSTATELADVLVREYGLPFRTAHRIVGRAVRHGSLDLATLEAAAREAADFSVVELGLTREKIDAVLDPRHAVAVRNIVGGPAPEAVAAQISEQRNLLARDKAWAEETESALSGAFEHLILEARRFAA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_BACCZ
Sequence: MNTKEISKVVDLVRESNPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVAEMTSIAGALVLNMGTLRPDEVEAMLLAGKSANMNDVPVLFDPVGAGATSYRTEVARHIPAEIELAIIRGNAAEIANVINEKWEIKGVDAGAGNGNVVSIAKQAADELNTVAVITGKEDVVTDGERTIVIRNGHSILTKVTGTGCLLTSVIGAFVAVEKDYAKAAVAALTFYGVAAELAAAKTVEKGPGSFQIEFLNQLANTTSSDIEKYGKIEVI
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: G6PI_CLOP1
Sequence: MKKGLVVDLSKAAPYLKSHEVAYMQETINQAHNKLHNGTGAGNDFLGWVDLPVNYDKDEFARIKEAAKKIQSDSDVLVVIGIGGSYLGARAAIEMLTNNFYNSMSKDKRKTPAIFYAGNNISSSYMADLLKAIDGLDVSLNVISKSGTTTEPAIAFRILKDYMEKKYGKEEAKKRIYATTDAKKGALKTLADAEGYETFVIPDDVGGRFSVLTAVGLLPIAAAGINIDEMMEGAADAREEYANPSLADNECYKYAAARNALYNKGKAIEILVNYEPSVHYFNEWWKQLYGESEGKDNKGLFPAAVDFSTDLHSMGQYIQEGRRDIFETVINVGSPREEIVIEANDENIDGLNFLAGKTMDYVNKQAFRGTLLAHNDGEVPNVVVNVPELTPYYFGRLVYFFEKACGISGYVLGINPFDQPGVEAYKKNMFALLGKPGFEDLKAELEERLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_CHLMU
Sequence: MATLRQVFSISELRQKIFFTFSLLALCRIGVFIPVPGINGDRAVAYFNQLLGSSQNLFQLADIFSGGAFAQMTVIALGVVPYISASIIVQLLVVFMPTLQREMREAPDQGKRKLGRMTRLFTLLLACVQSLLFAKFALRMNLVVPGIVLPAMLSLKLFGIPCVFYLTTVVVMTTGTLLLMWIGEQISDKGIGNGISLIITLGMLASFPSVLGSIFNKLNLGSQDPSEFGIVSLLVLCAVFVFVLMATVLIIEGVRKVPVQHARRIIGRREVLGGGSYLPLKVNYAGVIPVIFASSLLMFPATIGQFLSSESSWLKRIATMLSPGSVVYSIFYVLLIIFFTYFWTATQFRPEQIASEMKKNGAFIPGIRQGKPTQSYLEYTMNRVTLLGAVFLAVVAILPSILGRILRVDANVSYFLGGTAMLIVVGVVLDTMKQIDAFLLVRRYDGVLKKDRPKGRR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPR_CHLT2
Sequence: MKNQEESGWQAFLTLCSKMQKEKFLQDLFSLFLSFGERKDVASRYHIIRALLEGELTQREIAEKYGVSIAQITRGSNALKGSDPQFKEFLQKEI
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
What are the official names of this protein?
Trp operon repressor homolog.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBX31_CAEEL
Sequence: MTSQYSNYSCPLNNIQVNVIGSSRTSDDHFLEQMLTKRKKTNISQDLHYLLLGLNPRELYQISFKLARIDEKKYKFNGNFNEGDYYPHKNSEIPMEDTEEIVHSDGYQTGARWMKTGVYFPKIGISKEQPDKERCLLLESLHAYFPVLVFTTSSGISLEVPVWSQKFVTTMTSSNRSVKRREKRKLEETAGPAAKKTPDIIETTPEDVVPEVYNAQYFYQMQNNTVISSESKFSSPLALQQDLTEDFGTFAQLDAHFNVSVQSCSSSSLSSPAALKHDSTVSSDSDFDDKNSEEFDAVFEYIDQQFSNHDQNPMDQQSKSIDLNQTTWAPQSINNPGYLSTASSPAALNQDSSASEKSSIVRDKKSDENCLDEFDRVFNELDQQFTPKEDQVQDLSNCTTWNQEPINNSIQSNQFINPELFYFIFHKCLIISWPSCLSCCRGSILPQHLRTPPLVPISQLLIISPLVLPPYHNFTTGSATVSPFASTPANMTIFNFTSDSSTTYSNSTTAQVFPDVANTPDLSYFNIAPAVDLSLFIDPFVQSGRDLSIERSIRNFTNTLKKAHRQKKTAILTFQSTEPMQLEFKYCTKMLLRTDKPVGNFSIQLSGPYLEHLLNLSHHLCRFSEYNLFVKAHFPRGSYGSLTSMTGPAVEIPETQENITIIWVKKDFPENVNKYPVAINSLITEAIASNGTNQVLLTSKYPSDCTIRFRKCGFMIEGVLVVKKKETVIIDRQILGELNRLKHDLLQ
What are the official names of this protein?
Putative T-box protein 31.
What are the subcellular locations of this protein?
Nucleus.
Protein: CMAH_PANTR
Sequence: MGSIEQTTEILLCLSPVEVASLKEGINFFRNKSTGKDYILYKNKSRLRACKNMCKHQGGLFIKDIEDLAGRSVRCTKHNWKLDVSTMKYINPPESFCQDELVVEMDENNRLLLLELNPPNPWDLQPRSPEELAFGEVQITYLTHACMDLKLGDKRMVFDPWLIGPAFARGWWLLHEPPSDWLERLCQADLIYISHLHSDHLSYPTLKKLAGRRPDIPIYVGNTERPVFWNLNQSGVQLTNINVVPFGIWQQVDKNLRFMILMDGVHPEMDTCIIVEYKGHKILNTVDCTRPNGGRLPMKVALMMSDFAGGASGFPMTFSGGKFTEEWKAQFIKTERKKLLNYKARLVKNLQPRIYCPFAGYFVESHPSDKYIKETNTKNDPNELNNLIKKNSDVITWTPRPGATLDLGRMLKDPTDSKGIIEPPEGTKIYKDSWDFEPYLEILNAAVGDEIFLHSSWIKEYFTWAGFKDYNLVVRMIETDEDFNPFPGGYDYLVDFLDLSFPKERPQREHPYEEIHSRVDVIRHVVKNGLLWDELYIGFQTRLQRDPDIYHHLFWNHFQIKLPLTPPNWKSFLMCCEQNGPGILQECKTT
What is the function of this protein?
Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions.  Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.
What are the official names of this protein?
Cytidine monophosphate-N-acetylneuraminic acid hydroxylase, CMP-N-acetylneuraminic acid hydroxylase, CMP-N-acetylneuraminate monooxygenase, CMP-Neu5Ac hydroxylase, CMP-NeuAc hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the CMP-Neu5Ac hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_ECOLU
Sequence: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: ARGB_SALTI
Sequence: MMNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGLFLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTDDGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_POLNS
Sequence: MSGNTLGLLFTVTTFGESHGPAIGAVADGCPPGMLLTEADIQLDLDRRKPGTSRHVTQRKEEDKVEILSGVFEGKTTGTPIALLIRNTDQRSQDYGDILQTFRPGHADYAYQYKYGIRDPRGGGRSSARLTAPVVAAAVIAKKWLHEKYGTEFYGYMSQLGELEIPFKDASEIEKNPFFAANAELIPQLETYMDELRRAGDSCGARIEVRARNVPAGLGEPLFDKLDADIAHAMMGINAVKGVEIGAGFRSVVQRGSEHGDELHSDGFASNNSGGTLGGISSGQDLRVSIAIKPTSSIMSPKQSVDLSGKPIIVQTKGRHDPCVGIRATPIAEAMLALVLMDHVLRHRAQCADVSTSISPIPASQPGSFHD
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL32_SHESR
Sequence: MAVQQNKKSRSKRGMRRSHDALSTAQLSVDATSGEVHMRHNVTADGFYRGKKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SYM_BACC2
Sequence: MSIFIGGAWPYANGSLHLGHIASLLPGDILARYYRAKGENVLYVSGSDCNGTPIAIRAKQEGVTAKEIANKYHEEFQRCFRDLGFTYDCYTRTDSEHHHETVQKVFLRLLEEGYIYKKTVEQAYCKTCTQFLPDRYVEGICPHCHEAARGDQCDACSAILDPLDLLEKTCKLCGSTPSVEETEHFYFALHTFQQQIKKVVEIAKEKGTWRDNAIQLTERYVKEGLQDRVVSRDLPIGVPIPVKGYEDKKIYVWIEAVAGYYSASKYWAEETGKDDHEFWNSDAQTYYVHGKDNIPFHSIIWPAVLLGIGEEAIPRHIVSNEYLTVEKRKLSTSKNWAVWVPDILERYNPDSIRYFLTVNAPENRDTDFSWREFIYSHNSELLGAYGNFVNRTLKFIEKYYDGIVPQGTINVELKDKVEGLYKNVGEAIEQTTFKVALETIFDAVRFANKYFDERQPWKEREDNPVSCEETIYNCIYLIANFANLLEPFLPFSSERVRSTLSIVNRNWEPQNTLPNRIDSVQPLFERIDVKQIEHEIEKLYGAAK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.