PharMolix/UniProtQA huggingface dataset:
Protein: RS7_CHLTB
Sequence: MSRRHAAEKKVIPGDPVYGSVVLERFINKVMLHGKKSIARKIVYGALERFAKRLGLENPLEGFEEALENAKPILEVRSRRVGGATYQVPVEVAPDRRSCLAMQWIIKHARSKPGKCMEVGLANELIDCFNKQGATIKKREDTHRMAEANKAFAHYKW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TILS_GLOVI
Sequence: MTRWWAAVSDLSLRRRLRPALGLLPPGSGLLVAVSGGQDSLCLLKLLVDLAPERGLHLHVGHLDHRWRPGSERDAQRVAVLCNVWGVPFHLEIARTPPASEAAARAWRYCWLEQIARGLALERVVTGHTLSDRAETVLFNLLRGSGGAGLGSLDWERPLGGGVRLVRPLLGITRAETGAYCLAHHLPICIDESNANLTFRRNRIRLELMPYLREHFNPLVEQTLARTGDILHAESELLESLLDEHWHSLVQEGRLHRNTLAALPLALQRRAVRRWLSVGLGRQPNFEHIAAVLGCLSAPNRTRTSPLAHSLLVEVQGEWLGLVGG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APGM_PICTO
Sequence: MKNIVLLIMDGLGDNPNPEFFGKTALQAAYRPNLNALCRKSICGLMDPVGPGIRSGSDTSHLSILGYSPERYYNGRGPFEALGLGMELYPGDVAFRANYAYVSDGYVLDRRAGRIRDTCELSRAVSMEIEDVKITVKSGTEHRAAIVMHGPGLSSMVSDSDPHRENERPMEVRPLDKKAEKTARILNEFIKKSREILNKHPVNIKRMNQGLMPANEILIRGAGMVPDLEDFYDRYHLKAACISGTPLIKGICRLAGMDIINMDNLTGRVDENYSGIFEKAHELAKKYDFIIINIKGTDIAGHDRRPDIKRSVIENVDSAISKIINDLDDLLIIVTGDHSTPCNLGDHSGDPVPIMFSSNNIRSDNVMLFDETSVRNGSLRIRGLDVMKIALSLSNRSEKYGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: RELE3_CAUVC
Sequence: MKSVELGPRARRDLTKLRRWLLNRAPSAADRAIDLILSRAEQLAQHSDLGRRKSQNMRELYVSFGAHGYVLQYRVYPDAVVIARIRHSLERR
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its toxic effect is neutralized by coexpression with cognate antitoxin RelB3 but no other ParD or RelB antitoxin.
What are the official names of this protein?
Toxin RelE3.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family.
Protein: TPS1L_ARATH
Sequence: MNSLGGIRSWPANWRSTTASMTTTESVRKVPQVLTVAGSDSGAGAGIQADLKVCAARGVYCASVITAVTAQNTRGVQSVHLLPPEFISEQLKSVLSDFEFDVVKTGMLPSTEIVEVLLQNLSDFPVRALVVDPVMVSTSGHVLAGSSILSIFRERLLPIADIITPNVKEASALLDGFRIETVAEMRSAAKSLHEMGPRFVLVKGGDLPDSSDSVDVYFDGKEFHELRSPRIATRNTHGTGCTLASCIAAELAKGSSMLSAVKVAKRFVDNALDYSKDIVIGSGMQGPFDHFFGLKKDPQSSRCSIFNPDDLFLYAVTDSRMNKKWNRSIVDALKAAIEGGATIIQLREKEAETREFLEEAKACIDICRSHGVSLLINDRIDIALACDADGVHVGQSDMPVDLVRSLLGPDKIIGVSCKTPEQAHQAWKDGADYIGSGGVFPTNTKANNRTIGLDGLKEVCEASKLPVVAIGGIGISNAGSVMQIDAPNLKGVAVVSALFDQDCVLTQAKKLHKTLKESKRGI
What is the function of this protein?
Essential for thiamine biosynthesis.  Bifunctional enzyme that catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP and condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine biosynthetic bifunctional enzyme TH1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GL18A_MDBVW
Sequence: MSQITLIILILAIGFSCTKSHPINSTRDGEDSGTDLKNLLTEPANTTYATNSTLTRKELNSTIQPERNDEGSAIRKIMASKKDENITGQSEINTSAKSQPINSTRDGEDSGTDLKNLLTEPANTTYATNSTLTRKELNSSIPPERNDEGSAIRKIMASKKDEIITGQSEINTIAKSQPINSTRDGEDSGTDLKNLLTEPANTTYATNSTLTRKELNSSIPPERNDEGSAIRKIMASKKDEIITGQSEINTIAKSQPINSTRDGEDSGTDLKNLLTELANTTYLTNSTLTRKELNSIIQPERNDESSAIRKIMASKKDENVTGQSEINTSAKSQPINSTRDGEDSGTDLKNLLTDPANTTYATNSTLTRKELNSTIQPERNDETSAIRKIMASRKDENVTGQSEFNISTNSNLNTTTHHEDAVVSPTEKVYVPNNASSAELNVSSTIQPKEADATTSSANDIKKPAFPYCIILITFQIVTVGMIIYLVFRTMRKPCQSERAIPLNTFGFGNNSSHE
What is the function of this protein?
Involved in suppression of the insect cellular immune response.  Inhibits host hemocyte adhesion and phagocytosis.
What are the official names of this protein?
Mucin-like protein Glc1.8a.
What is the protein family that this protein belongs to?
Belongs to the polydnaviridae Glc1.8 protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: LDHB_PANTR
Sequence: MATLKEKLIAPVAEEEATIPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase B chain, LDH-B, LDH heart subunit, LDH-H.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion inner membrane; Peripheral membrane protein.
Protein: G3PT_BOVIN
Sequence: MSKRDIVLTNVTVVQLLRQPCPEPRVEAEPEPPAQPQPQPEPIKEEVPPPPPPPPAPKKVRELIVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDLEYMVYMFKYDSTHGRYKGNVEHKKGQLVVDNNEISVFQCKQPKEIPWKSVGSPFVVEATGVYLSLEETKAHIEAGAQRVVICAPSPDAPMFVMGVNEKEYNPSSMKIVSNASCTTNCLAPLAKVIHERFGILEGLMTTVHSYTATQKTVDGPSKKAWRDGRGAHQNIIPASTGAAKAVGKVIPDLKGKLTGMAFRVPTPDVSVVDLTCRLAQPTPYSAIKDAIKAAAKGPMAGILAYTEDEVVSTDFLSDTHSSIFDAKAGIALNDNFVKLISWYDNEYGYSNRVVDLVRYMFSRDK
What is the function of this protein?
May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon.  Required for sperm motility and male fertility (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific, Spermatogenic glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_RHOPB
Sequence: MSLLPETKLDVLLAHHASLENQLQSQVGADTYVKLMRELAELNPLIEAVKAYRQVGAERGEIDALLADAATDAEMRAMAEAEHAALEAQEAELAQQIRVALLPKDAMDDRNVMLEIRAGTGGDEASLFAGDLFRMYEKFAVLQGWSVEVVSASEGTMGGYKEIIAEVKGRGAFAKLKFESGVHRVQRVPDTETQGRIHTSAATVAVLPEVEEVDVDIKPDDLRIETMRAQGAGGQHVNKTESAIRITHIPTGLQVMMQDSRSQHKNRASAMNILRSRIYDAEQQRIDSVRSAERKEKVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLPQVIAGEALGELIDALTTEHQAAQLAAQGNAA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_HAHCH
Sequence: MQKPYVFQEIPVHRPNTPLLDKIDSPAQLRLLNEAELLQLAHELRAFLLYSVGQSGGHFGAGLGVVELTVALHYAFNTPEDRLVWDVGHQAYPHKILTGRREQMLTIRQKDGLAAFPRREESPYDTFGVGHSSTSISAALGMAIAARLQNQPRKAIAVIGDGAMTAGMAFEALNHAADTKADLLVILNDNDMSISRNVGGLSNYFARLLASKTYNQMRDSGKRVLQGAPSLMELARKTEEHFKGMVAPGTLFEELGFNYIGPIDGHDLPRLVETLNNIKELNGPQFLHVVTKKGKGFAHAESDPIGYHAINKIEPKPKVQDTAKAPKKPRYSNIFGQWLCDMAEQDASLVGITPAMCEGSDLIEFSKRFPERYYDVAIAEQHAVTLAAGLACDGAKPVVAIYSTFLQRAYDQLIHDVAIQNLDVLFAIDRAGLVGEDGPTHAGSFDLTFLRCIPNMLIMAPSDEDETRKMLTTGYQYTGPAAVRYPRGNGPGADISPGLESLEIGKANLRRRGAQTVILNFGALLPAALGVAEESNFTVVDMRFIKPLDQNMILEMAGSHDLLVTLEENCILGGAGSGVIEFLASQGIAMPVLQLGLPDEFIEHGKPAELHKEVGLDAQGIANAIKKRLKSLNLASPKTGTSA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: CA1A_CONLG
Sequence: EGCCSNPACRTNHPEVCD
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This peptide is active on neuronal nAChRs alpha-7/CHRNA7 (IC(50) of 3. 24 uM), alpha-3-beta-4/CHRNA3-CHRNB4, alpha-4-beta-2/CHRNA4-CHRNB2, and alpha-4-beta-4/CHRNA4-CHRNB4.  10 uM of this peptide inhibits these receptors by 85%, 40%, 19%, and 13%, respectively.
What are the official names of this protein?
Alpha-conotoxin Lo1a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TOP1P_MIMIV
Sequence: MSILILLESPGKISKISSILGKNYVVKASMGHFRDLDPKKMSIDFDNDFEPVYIVTKPDVVKNLKSAMKNIDLVYLAADEDREGEAIAQSLYDVLKPSNYKRLRFNAITKDAIMSAIKNAGDIDKNLVDAQKARRVLDRLFGYLISPILQRQIGGKLSAGRVQSVTVRIIIDKENEIKNFINKNADSSYFKVSGTFNGAKATLHESNDKKPFDLETAYKGKTAQIALINSENPNSKVVNFMKRCLKSQFFIHSVEDKMTTRSPAPPFTTSTLQQEANRKFGMSIDSTMKTAQKLYEGGYITYMRTDSVEISAEGHRDIKKIITDQYGADYYQKNLYKNKAANSQEAHEAIRPTHPELLTLEGEIEDAYQIKLYKLIWQRTIASQMKPAKIKVTIIQISISKYVEDKLNPFYYFQSQIETVVFPGFMKVYVESIDDPDTDNQITKNFTGKIPTVGSKVTMEEIIARQEYMRPPPRYSEASLVKKLEELGIGRPSTYVNTIKTIINREYVKITDVPGIKKDITIYSIKSENKKHIMEVYEDTDTILLGKENKKIVPTNLGITVNDFLMKYFPEFLDYKFTANMETDLDYVSTGTKNWVDIVQDFYDKLKPIVDELSKQKGLSQSSERLLGEDNDGNEITATKTKFGPVVRKKIGDKYVYAKIKDPLTLDTIKLSDAIKLLEYPKNLGQYKGFDVLLQKGDYGFYLSYNKENFSLGEIDDPEDINLDTAIKAIEAKKANNIAEFNLTENGKKIKAIVLNGKYGYYVQVTRNRIKKNYPIPKDLDPNNLTEQQILSIISVKKTYKKSAPKGGSKTIRKPSQTKYSQTKSTKSTKSTKSTNKKFVGKSAKKTTKKTTKK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).
What are the official names of this protein?
DNA topoisomerase 1 type prokaryotic.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
What are the subcellular locations of this protein?
Virion.
Protein: ACPS_GEOSW
Sequence: MIIGIGIDIVELERIEQLMMKNEKFIDRILTEEEKRIFFQLSPKRKVEFLAGRFAAKEAYAKAIGTGIGKNVSFHDIQIMNDDNGKPIVVSNGKDCRIHVSISHSRDYAIAQVIIERLS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THB_ENTTH
Sequence: KKNMLLVNPIVGIGGLFVGAPMLTANLGISSYAAKKVIDDINTGSAVATIIALVTAVVGGGLITAGIVATTKSLIKKYGAKYSAAW
What is the function of this protein?
Cyclopeptide antibiotic with bacteriolytic activity against the Gram-positive bacteria S. aureus and S. thermophilus, and lower activity against the Gram-negative bacteria E. coli and P. aeruginosa.
What are the official names of this protein?
Bacteriocin thailandicin.
What are the subcellular locations of this protein?
Secreted.
Protein: CSPLC_ARALL
Sequence: MAREKIVVAGGSTKSWKLLLGLRVFAFMATLAAAIVMSLNKETKTLVVATIGTLPIKATLTAKFQDTPAFVFFVIANVMVSFHNLLMIVLQIFSRKLEYKGVRLLSIAILDMLNATLVSAAANAAVFVAELGKNGNKHAKWNKVCDRFATYCDHGAGALIAAFAGVILMLLVSSVSISRLLINSKHLSTTATTTAVV
What are the official names of this protein?
CASP-like protein 1B2, AlCASPL1B2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VA552_SCODE
Sequence: MNILLSSTLFVLLMFQIIGSGMGCDMKVRGLDANMKKMILDLHNKKRQIVANGQQSGQPLAANMKELHWDDEIEAIAQRSAETCVFKHTAKSLRKSSKYSYLGENVYKGGYPDPIPRSVNKWYDEVKDVTPAVVKSFSDDGPMIGHYTQMVWANTEALGCGLVTASDGTSYLFCQYGPGGNYPGQQIYKQGPPGSGCKNGKSSKYPGLCN
What are the official names of this protein?
Scoloptoxin SSD552, Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family. Venom allergen 5-like subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y633_MYCPN
Sequence: MRYLDLNIKSILADWEIADAIRELIANAIDEHRLSNTAFPVIELQKGFLNSSLVIKDYGRGIKSNHFIQNESREKVQSEKTIGKFGIGLKDAIAVLFRHNVKVSFTSSEGTFTPVERMKEGMKDGTKTIQITVDETKKIDKGTDILISKISRSDYEKAIAIFLELRTGYQKLASSKKGDIYRSENGSEIFLNGMKIGTDENFLFSYDIKEPNKKLQKSLNRERKTLSRDSYRDNIISILKSSINKNT
What are the official names of this protein?
Uncharacterized protein MPN_633.
What is the protein family that this protein belongs to?
To M.pneumoniae MPN_635 N-terminal region.
Protein: RECO_RHOP5
Sequence: MEWTDDGIVLGVRRHGESSAIVELLTRAHGRHLGLVRGGAGSKLRPVLQPGNSVHAGWRARLDEHLGYYALEGMRLRAATLLAVPHAAYGITHLAALARLLPERDPHPEMYETVERILEDFDDATMAGAHLVRFELAMLGELGFGLDLSACAATGVTSDLIYVSPKSGGAVSRTAGEPWRDKLLRLPPFLREDEDAAGCTADDLRDGFALTGRFLLRNVLEPRGQGHSDARDGFINAVTRPRGQGALPVVALPDPMGR
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PURT_FRATF
Sequence: MNISNIKIMLLGSGELGKEFIIAAQRLGIHTIAVDRYKNAPAMQVAHESYVIDMLNSDALEQLILAKNPTYIVPEIEAINTDSLVKLEAHNFNIIPCAKATKLTMDRQGIRALAVQQLNLQTSKFAFANSEQEYLDVIQSIGLPFVIKPVMSSSGKGQSIVKEHNEIKKAWDYAQNGSRGHAKGVIVEQFIDFDYEITLLTVRHKDGTSFCDPIGHIQKDGDYRFSWQPHTMPDTALAKSQEIAKEITDALGGYGVFGVELFIKGDEVFFNEVSPRPHDTGMVTLISQNINEFELHLRAIVGLPIPDIQTLQPSASAAILLEGDTANASICGIDKALADANVDIRIFSKKEIHGKRRMGVVLAKAQNTHIALETSKQALAHIHLTK
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: TM11D_MOUSE
Sequence: MYRPRPMLSPSRFFTPFAVAFVVIITVGLLAMMAGLLIHFLAFDKKAYFYHSSFQILNVEYTEALNSPATHEYRTLSERIEAMITDEFRGSSLKSEFIRTHVVKLRKEGTGVVADVVMKFRSSKRNNRKVMKTRIQSVLRRLSSSGNLEIAPSNEITSLTDQDTENVLTQECGARPDLITLSEERIIGGMQAEPGDWPWQVSLQLNNVHHCGGALISNMWVLTAAHCFKSYPNPQYWTATFGVSTMSPRLRVRVRAILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAATQNIIPGSVAYVTGWGSLTYGGNAVTNLRQGEVRIISSEECNTPAGYSGSVLPGMLCAGMRSGAVDACQGDSGGPLVQEDSRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWIRQQTGI
What is the function of this protein?
May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.  Preferentially cleaves the C-terminal side of arginine residues at the P1 position of certain peptides (By similarity).  Plays a role in the proteolytic processing of ACE2.  Isoform 2 may play a key role in regulating adrenal proliferation by specifically cleaving N-POMC.
What are the official names of this protein?
Transmembrane protease serine 11D, Adrenal secretory serine protease, AsP, Airway trypsin-like protease, AT.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Transmembrane protease serine 11D catalytic chain]: Secreted. Note=Activated by cleavage and secreted.
Protein: ATPF_CUCSA
Sequence: MKNVTDSFISLGYWPSAESFGFNTDILATNPINLSVVLGVLIFFGKGVLSDLLDNRKQRILKTIQNSEELRGGAIEQLEKARARLRKVEMEADQFRVNGYSEIEREKLNLINSTSKSLEQLENYKNETIRFEQQKAINQVRQQVFQQALQGALGTLNSCLDNELHLRTISANIGMFGTMKEITN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MYG_HEMJP
Sequence: MABWDKVNSVWSAVEQNITAIGQNILLRLFEQYPESEDYFPKLKNKSLGELKDTADIKAQADTVLRALGNIVKKKGDHSQPVKALAATHITTHKIPPHYFTKITTIAVGVLSEMYPSEMNAQAQAAFSGAFKNICSDIEKEYKAANFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GCH1L_LISMO
Sequence: MKVANGYEYTAIMEKIAPKKLAMEGDPIGLQVGDLSRKVRKIMFTLDVLEEVVDEAIEKKVDLIIAHHPFLYRPTQHIDTTTKQGKMIKKLIKHDITVFAAHTNLDIAQGGVNNILADLLHLQNTTMIEETYSEPYCKIAVYVPENELESVRLALVNNGAGQIGTEYTECTFHTTGIGSFKPGANANPTIGEKDALTSVPEVKIEAIFPQYLTETITKAVKIAHPYEEPAIDVYTLEMQTYKEGLGRVGMLPKKLGMVSFIDKLKTAFAIDNVRFIGDLKTTVHKVAIIGGDGNKFIHQAKSTGADVFITGDVYYHTGHDLLAINLPTIDAGHNIEKVMKGYLKNKMEEQAKILDYEAEFIVSEVNTDPFQFC
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: FGF1_CYNPY
Sequence: EITTFAALTERFNLPNGNYQRPKLLYCSNGGHFLRILPDGKVDGTRDRSDPYIQLQFYAESVGEVYIKSLETGQYLAMDSDGRLYASQSPSEECLFLERLEENHYNTYKSKMHADKDWFVGIKKNGKTKLGSRTHFGQKAILFLPLPV
What is the function of this protein?
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.  Functions as potent mitogen in vitro.  Acts as a ligand for FGFR1 and integrins.  Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades.  Binds to integrins.  Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
What are the official names of this protein?
Fibroblast growth factor 1, FGF-1, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, HBGF-1.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery (By similarity).
Protein: RS11_RICBR
Sequence: MNQTVKAKKKKKTITLGVVHIRASFNNTIVTFTDVQGNAISSASAGANGFKGAKKATPYAAQITIDKAAEKAKEYGLKTISIRIGGPGAQRESAMRALFGQNFVVTSILDVSSIAHNGVKAPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HISZ_CLOBL
Sequence: MENWNKYIPEGMKDILFEESNIKLNIEDQLRKIYKYSGFSEIISPTIEFYDVFNSNIQAIPQEKMYKLFDNLGRILVLRPDMTTPIGRITGTKMKDCTYPLKLCYTANIFRVNEKLNGKRGEITQSGIEIIGTNGIKSDVDSIVTAINTLLSLGLKNFKIELGEAGFFQALTENMEIKEENLKKLKEIIRNKNYVALKKFLDEISSKYSKEDFELIKNLPKLFGDIKIIEKAKALTKNKKALKSLDDIYNIYKSIENIGLEAYISIDLGMVQNIDYYTGVIFKGYVEEVGDSILSGGRYDNLIQHFGIELPATGFAINVDDIMIALKKQNTMSMDKDKKVLIFYKEEFLRKAYDFMQELKMKKIICELSLLDDDKEILLYSKKKGIDFIIGFMGEEKLFVKDLKSDKIAFLKKDEIENLLML
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_ASACA
Sequence: GVGFKAGVKDYKLTYYTPDYETLATDILAAFRVXPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLLAKNYGRADYECIRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWXNAPGAVANRVALEACVQARNEGRDLAREGNEVIREASKWSPELAAACEIWKEIIFEFEAMDAL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AZOR_CERSK
Sequence: MTTILRIDSSIKGEAAVSRRLTQRILDRLLEAHPDATVVSRDLAQGIRQIDGSWLGSVFTAPEQRTADQQEIARTADAVMAEVKEADILVIALPVYNFGAPAQLKSWVDHIARRGESFVYTETGPVGLLTGKRAIVAFTSDGTPLGSELDHASGWLRQVLGFVGITDVDFVAADRMVFGADEAMARAEAAVAALAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.