PharMolix/UniProtQA huggingface dataset:
Protein: CEP97_MOUSE
Sequence: MAVARVDGALAPGEGSVVNWSGQGLQKLGANLPCEADVHTLILDKNQIIKLENLEKCKQLIQLSVANNRLVRMMGVAKLTQLRVLNLPHNSIGCVEGLKDLVHLEWLNLAGNNLKTMEQVNSCTALQHLDLSDNNIPQIGDVSKLISLKTLLLHGNIITSLRMAPAYLPRNLSILSLAENEIRDLNEISFLASLSELEQLSIMNNPCVMATPSIPGFDYRPFIVSWCLNLRVLDGYVISQKESLKAEWLYSQGKGRSYRPGQHIQLVQYLATVCPLTSALGLQTAEDAKLEKILSKQRFHQRQLMSQSQDEELSPLAAVETRVHRTPECSSPGQDFQESEPVLQINSWVGISSNDDQLYAVKNNFPAAAHAARYSRNDLHLEDIQTDEDKLNCSLLSSESTFMPVASGLSPVSPTVELRLQGINLGLEDDDGADEFTKGLENQDEDKDKEKSLWDMSESCVEMLKRKISTEVSEAAGLLPCPKSVIISAALKEDTHSLTSLPESAGHSASRTEANSEEAMSPATSEKFPCRILTQRPAALGQDKVTLQKLNAAATKLQACWRGFYTRNYNQQAKGVRYEIRLRRMQEHIVCLTDEVRRLRKERDEERVKTFVQEEAVRFLWNEVRSVQAWQQTVEQRLASWPPDVPPISSTLASPKPPLFPHHQDPSSDQSSDWLVAEDEAAQGRSAPDFPDSGFHSSLTEQVPCLQDSLDFEKSSVESSENSVLGNSADTVKCVKDRDSEATAEEHSDCSRESSASEQDNTLLQQYLTSVQQLDDAAEAADSDDVAGDGKRHLACSPERFDASSDSETHRVASTSQDEISQTPENCQLNEEAQGQPPECDPAFQGLHVGVTVQPV
What is the function of this protein?
Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation.  Required for recruitment of CCP110 to the centrosome (By similarity).
What are the official names of this protein?
Centrosomal protein of 97 kDa, Cep97, Leucine-rich repeat and IQ domain-containing protein 2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Recruited at the distal end of the mother centriole by MPHOSPH9.
Protein: RL23_UREP2
Sequence: MELTRVILHPYTTEKTYSIRNKSEHETLTFIVDKNANKYQIREAFIAIFGLKPLKIRTTNRRPAKIRTSTARPGYTKAKKIAYVVMPVGVKVAVSKEEVEAANAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: WDR12_DROVI
Sequence: MEAENGEGQVQVHLKTKQEHYAVPDVPYAIDGSVSTTELNIFLNALLQSKGAEGVDFDFLVFDEYLRGRLCDHLREKAISFEDAIDIEYVERFPAPEPQDCLLHDDWVSAVKACGKWILTGCYDNTINIWTNKGKHKLTIPGHTAPIKAVDWISMDDENGRFVSTSQDQTAMLWQWNIASNAVECVSVCKGHERGVDSVCVSPDAQRFATGSWDTMLKIWSAGLDDTSEGTAKRVKESGVRTPKMTLQGHRESISAVQWMDATTLVTGSWDHTLKVWDLQLEGIKTEISTNKSIFDASYSKLNRLIVTASADKNLRLYDARTNQGSVVRNTYLGHNAWVQTVMWSNTEEFLFVSGSYDTQNKLWDCRSPKAPLYDLLGHGEKVLDIDWSNPKYIVSGGADNTVRVFKSGKATIENMETK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: KTHY_MYCMS
Sequence: MFITFEGMDGSGKTTTLLKVKEELERLNYQVLITREPGGEAIAEQIRQIILDNKNRDMDAWTEALLFIASRNQHLQKVIKPALEKNIIVISDRFIDSTSAYQGSARNIGVDVVNQVQQIVLKNCLPDLTLFFDVSFSEAEKRMQIRGENSKNRLDEEKSDFKQKVYQGYLELVKNNPKRIKVIDANQDIDQVYNQAIKIILEKLKENEKRTSN
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: MNME_CUPPJ
Sequence: MTAPLPPIAAIATAPGRGGIGVVRVSGPDVRPVMHAICGQALKPRHATYLPFLDGHGKVIDHGLALYFPGPNSYTGEEVLELQGHGGPVVMQMLLTRCLQAGHGIGLRLAEPGEFTRRAFLNDKLDLAQAEAVADLIEASTEAAARSAARSMEGEFSHAIHTLVEKVIHLRMLVEATLDFPEEEIDFLEASDARGQLATIRNDLGNVLAQARQGALLREGLSVVLAGQPNVGKSSLLNALAGAELAIVTPIAGTTRDRVKETIQIEGIPLHIIDTAGLRDEATDEVERIGIERTWDAIRRADIVLHLVDATDYLRHGLSEIDDAIDDRLSGQLPPGAPIVRVVNKIDVAPTVGGMMFSGNRPHVVAANGPNPTEIWISARTGSGIELLRKELLRLVGWQSGNEGTFLARERHLTALRQAQSHLDVAAEQSERQAQALDLFAEELRLAQEHLNSITGEFTSDDLLGTIFTRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBOA1_MOUSE
Sequence: MAARPPASLSYRTTGSTCLHPLSQLLGIPLDQVNFVACQLFALSAAFWFRIYLHPGKASPEVRHTLATILGIYFVVFCFGWYAVHLFVLVLMCYGVMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRKAEDLSAEQHRLAVKAKPSLLEYLSYHLNFMSVIAGPCNNFKDYVAFIEGRHIHMKLLEVNWTQRGFQSLPEPSPMGAVIQKLCVTLMSLLLFLTLSKSFPVTFLIDDWFVHKANFLSRLWYLYVVMQAAKPKYYFAWTLADAVHNAAGFGFNGMDTDGKSRWDLLSNLNIWKIETATSFKMYLENWNIQTSTWLKCVCYERVPWYPTVLTFLLSALWHGVYPGYYFTFLTGVPVTLAARAVRNNYRHHFLSSKARKIAYDVVTWAVTQLAVSYTAAPFVMLAVEPTISLYKSVFFFLHIICLLIILFLPIKPHQPQRQSRSPNSVKKKAD
What is the function of this protein?
Acyltransferase which catalyzes the transfert of an acyl group from an acyl-CoA towards a lysophospholipid producing a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (PubMed:18287005).  Acts on lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) and lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE), and to a lesser extend lysophosphatidylcholine (PubMed:18287005).  Prefers oleoyl-CoA as the acyl donor and 1-oleoyl-LPE as acceptor (PubMed:18287005).  May play a role in neurite outgrowth during neuronal differentiation (PubMed:27048541).
What are the official names of this protein?
Lysophospholipid acyltransferase 1, LPLAT 1, 1-acylglycerophosphocholine O-acyltransferase, 1-acylglycerophosphoethanolamine O-acyltransferase MBOAT1, 1-acylglycerophosphoserine O-acyltransferase MBOAT1, Lysophosphatidylethanolamine acyltransferase 1, LPE acyltransferase 1, LPEAT1, Lyso-PE acyltransferase, Lysophosphatidylserine acyltransferase, LPSAT, Lyso-PS acyltransferase, Membrane-bound O-acyltransferase domain-containing protein 1, O-acyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: ACYP_ACIC1
Sequence: MTDVARPDVQACEQVRLTAWVRGRVQGVGFRWWVRARALELGLTGVARNLPDSRVEVVAEGPRERCAELLELLSGVPRHGRPGFVAGVTAEWSTARGGYSGFTQA
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: SYH_LACCB
Sequence: MNYQRPKGTADILPGQSERWQQVEAVARKIFAQYQYHEIRTPIFENVDVFSRSAGDTSDIVTKEMYTFKDKGDRMMALRPEGTAGVVRAYVENKLYGPEHAKPYKVYYLGPMFRYERPQSGRQRQFHQIGVEAFGSDSPVLDAETLALAKQLLEALGAKHLKFVINSLGDPATRKAFHAALVDYLTPFKDQLSEDSKVRLVKNPLRILDSKDKHDQEIVANAPSILDYLTPEAQQHFDRVKTLLQGLGIPFEVDATMVRGLDYYNHTIFEVMSDDKVFGGGYTTILAGGRYNGLVEELGGPETPGIGFAMGVERLMLLMQGELPTAQPDAYIVTIDQGADQEALQMLTAIRQQGFTGEMDYMGRKPKGQFKAANKANAKLVLTIGESERAAGTVQIKNMATGDQQAFPQADVLADFGKIYTQVMEAK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S11_HYDSC
Sequence: MTCCNQQSSQPKTTTNCAESSCYKKTWSDHRGTRIERGCGCPQVKPGIKLECCHTNECNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 1, Toxin 4.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DER_CERS5
Sequence: MSFTLAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDLREGDARLIDLRFTVIDTAGLEEVTDDSLQGRMRRLTERAVEMADVCLFLIDGRVGVTPSDEVFADILRKKNAHVILGVNKAEGRAGDAGAIEAWSLGLGEPVRLSAEHGEGMDDLYHILRPIAEGFAERAAADAPVVDVDVSEEEADLEADPDAHKPTVKRPLQIAVIGRPNAGKSTLINKIIGEDRLLTGPEAGITRDAISVRSEWQGTPIRIFDTAGMRKKARISDKLEKLSVADGLRAVRFAEVVVVLLDVEIPFEQQDLRIADFAETEGRAVVVAVNKWDLEGEKQEKLAELKEMFDRLLPQLRGAPLVTVSAKTGRGLDRLHAAILKAHDIWNRRITTARLNSWLGAMVEAHPPPAPGGRRIKLRYMTQVKTRPPGFVVMCSHPDEMPDSYRRYLVNGLRDHFDMPGTPIRLTMRGQGDKNPFKERKFRTPSRLRKHLGKKG
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL331_MYCSS
Sequence: MASSTDVRPKITLACEVCKHRNYITKKNRRNDPDRLELKKFCPNCGTHRAHKESR
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: M3K7_BOVIN
Sequence: MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDITSTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSESGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIAATTGNGQPRRRSIQDLTVTGTDPGQVSSRSSSPSVRMITTSGPTSEKPARSHPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  Plays an important role in the cascades of cellular responses evoked by changes in the environment.  Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR).  Ceramides are also able to activate MAP3K7/TAK1.  Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7.  These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK).  Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK.  MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis.  In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B (By similarity).  Promotes TRIM5 capsid-specific restriction activity (By similarity).  Phosphorylates RIPK1 at 'Ser-321' which positively regulates RIPK1 interaction with RIPK3 to promote necroptosis but negatively regulates RIPK1 kinase activity and its interaction with FADD to mediate apoptosis (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Although the majority of MAP3K7/TAK1 is found in the cytosol, when complexed with TAB1/MAP3K7IP1 and TAB2/MAP3K7IP2, it is also localized at the cell membrane.
Protein: ZN418_HUMAN
Sequence: MQGTVAFEDVAVNFSQEEWSLLSEVQRCLYHDVMLENWVLISSLGCWCGSEDEEAPSKKSISIQRVSQVSTPGAGVSPKKAHSCEMCGAILGDILHLADHQGTHHKQKLHRCEAWGNKLYDSSNRPHQNQYLGEKPYRSSVEEALFVKRCKFHVSEESSIFIQSGKDFLPSSGLLLQEATHTGEKSNSKPECESPFQWGDTHYSCGECMKHSSTKHVFVQQQRLPSREECYCWECGKSFSKYDSVSNHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGERPYECGECGKSFSQNGTLIKHQRVHTGERPYECEECGKCFTQKGNLIQHQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGKSFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRRVHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRECGKFFSSLLEHRRVHTGERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSFAETFSLTEHRRVHTGERPYECSECGKSFHRSSSLLRHQRVHTERSPYK
What is the function of this protein?
Transcriptional repressor.
What are the official names of this protein?
Zinc finger protein 418.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EX7S_RICAE
Sequence: MTNTKTLEANISFEEALKELEEIVKKIDKGQESLETAVNSFERGILLKNHCEKKLKEARLKIEKITKLADSTVVLEEMEV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_THET2
Sequence: MIRPLPPELRGLLARGEVLLTVKDAVRELLENALDAGARRVRVELWGGGLKRLVVEDDGEGIPLEDLPLAVEPYATSKLQDLEGIRTLGFRGQALYALRQAARLRIRSRPRGQLGGGLLLAEGERVEVRPVPAPPGTRVEVEGLFLGEGRDPKGEVRGVLELLKRYLLHHPRLALALFAEGEARLLFPGAGLEEAARLAFGRLLAKRLLPLAYGAGGLEVQGLVSRPEVSRTRPDRLFLAVNGRPVAFPEGLLRRVRRAYRELLPEGHYPVGVLNLFLPQEAFRLRLDARKEEVVLSEEAEALVEEALLALFRRENLARALPEPKPLQPLSPPTASGLPRLRFLAQFRESYLLAEAGDTLYVVDQHAAHERILYEDLLKRVAEGPKPLPRPLLVLLAPEEEALLEAGQEALAALFRWEPFGPGRVRLLMAPAFLHPYPLLLPEVFKEALRGEGRSLKALLARLACLPAVKAGHPLGEAQGQALLDALLTCETPWACPHGRPVLLALKEEDLIRRFGRRSGARGGGEARPRPQEESFPEAPLPREP
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: AHLLA_BACTK
Sequence: MTVKKLYFIPAGRCMLDHSSVNSALTPGKLLNLPVWCYLLETEEGPILVDTGMPESAVNNEGLFNGTFVEGQILPKMTEEDRIVNILKRVGYEPDDLLYIISSHLHFDHAGGNGAFTNTPIIVQRTEYEAALHREEYMKECILPHLNYKIIEGDYEVVPGVQLLYTPGHSPGHQSLFIETEQSGSVLLTIDASYTKENFEDEVPFAGFDPELALSSIKRLKEVVKKEKPIIFFGHDIEQEKSCRVFPEYI
What is the function of this protein?
Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer.  Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL.
What are the official names of this protein?
N-acyl homoserine lactonase AiiA, AHL-lactonase AiiA.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: DMS6_PITAZ
Sequence: GLWSTIKQKGKEAAIAAAKAAGQAALGAL
What is the function of this protein?
Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria.  Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).
What are the official names of this protein?
Dermaseptin-H6, Dermaseptin-H1, Dermaseptin-like peptide 1, DMS1, Dermaseptin-like peptide 6, DMS6.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYIM_YEAST
Sequence: MKRSRLVPQHIFSIISKRYLAKHAYQKTLNLPKTKFPNRSNLEITLRELIPKSSQLVYKEQLRDFFEEFSKLNTTDEKLEFIKEKLFILHDGPPYANGELHLGHALNKILKDIINRYQLSQGKYIFYKPGWDCHGLPIEIKALKDLSAQQIESISPLKIRSMALKHAQKAIKRQRETFQHFAILTDWETPYLTMDKDYEINQLNIFKEMYERGLIKRQNKPVYWGTETRTALAEGELEYNENHKSIAAYVKFPLEKKSQMDLCKKLGITNNLPIYCLIWTSTPWTLLSNRAICFNQDFSYSLLRLNSELILVETGSIDKLGLTTNSFETIKQFQGTHLNGLYYQNLLVDDKVGRPLLHGAHVTSGTGTGLVHTAPGHGQDDYLIGIQNGLEIYSPVDHQGRYQLNELPQSVRSIVRDEGDLTKGRQVLDAETAKIILCKLSDLNLLYKSHEYTHSYPYDWRSKKPVIIRATPQWFADLHDVKNLALESISRVKFCPKRGYSRLSSFMKSRNEWCISRQRSWGIPILSFYKKSEPDSVLMNSEILAHAIEKIKQKGINAWFNDKDNDMKEWLPEKYHDVAHEYCRSQDTMDVWFDSGSSWSVIKDFYEKSLKLSKLPSPLYQVCLEGSDQHRGWFQSSLLTKVASSNVPVAPYEEVITHGFTLDENGLKMSKSVGNTISPEAIIRGDENLGLPALGVDGLRYLIAQSNFTTDIVAGPTVMKHVGEALKKVRLTFRYLLSNLQKSQDFNLLPIEQLRRVDQYTLYKINELLETTREHYQKYNFSKVLITLQYHLNNELSAFYFDISKDILYSNQISSLARRQVQTTLVHILNAYRAILAPILPVMVQEVWKYIPEGWLQGQEHIDINPMRGKWPFLDSNTEIVTSFENFELKILKQFQEEFKRLSLEEGVTKTTHSHVTIFTKHHLPFSSDELCDILQSSAVDILQMDDNNNSLPTIELGSGINVQILVERSKRHNCPRCWKANSAEEDKLCDRCKEAVDHLMS
What are the official names of this protein?
Isoleucine--tRNA ligase, mitochondrial, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: BRL2_SCHPO
Sequence: MYQNGKPDAPTILGQKRELEDVEIQDDDIQEVSKEDLLKDVRVRSIQFDELESKIEGLQNLAEEKLKVLATLVSWWPEILQQFSVVFQGNELKDFESEGVFSILEKFPELSYFNDAVKNNKTKALSIIQKLLSTVDSSTNSVSRDPFSVLSIDDSALTEKLNTINLDIDKILDELDTTRSQLHSIIKLPDRSSSFTLQCINESVRPQSTKVKEEATTSSKGKDEEKKVSTVEQRTQLQQLSRLQDQQNGLMESRSQSLKILDSNVNEMDKLIMERENALNNVETTNLKKYSSFLALKEAVSMTSEQLRVLEHLLSECSHEINVLSQQSKNFNGVFESSYQPLINDLDHQISVMQNDEKRINNAKTELSLSLEKKLEAKKQKEKVYKDKLDELANLETMVLEKKKAVATREAANKIRLVDLNDLELQKDLSTYLSKELASTEKAFRLVKQQTVKSSHSHYQELITKFSVEKEKAEQKYFLTMKSTDSLHAEVKLLRQKYQKTNEIISKMLNSQDTAVHRIIEFEDQLARLSSVRNNSIKQSTTFQVKKSSQKSTIQNLEEKVSYLQQFMDKNNATLTDLEFQCSDLSSSIDILSKQDEEHEKEKRKLKDTGVSTSAEELKTFRAMCKCSVCNFERWKDRIISLCGHGFCYQCIQKRIETRQRRCPICGRGFGASDVIPIHL
What is the function of this protein?
E3 ubiquitin-protein ligase which belongs to the histone H2B ubiquitin ligase complex (HULC) which mediates monoubiquitination of histone H2B to form H2BK123ub1.  H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
What are the official names of this protein?
E3 ubiquitin-protein ligase brl2, BRE1-like protein 2, RING finger protein 1, RING-type E3 ubiquitin transferase brl2.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
Protein: MURC_CLOBK
Sequence: MSFDFIKDKNKHIHFIGIGGISMSGLAEILLYNNFSISGSDMNSSPITEKLKDKGAKIYIGHKKENVKNADLIVYTAAIASDNPEIIEAKEKNIKLMDRADFLGNLMKGYKYNIAISGTHGKTTTTSMLSHVALKANVDPTILVGGNLDIINGNVRVGESDFFITEACEYKSSFLKFFPYIGVILNIDADHLDYYKDLDDIKNAFSKFIKLIPKDGYLVAYGEDKNIQSIIKEANCNVITYGINSGDIQAHNIEYDEKACGNFDVVKDNQKLFSVKLNVPGKHNILNSLASICIGLASDMKDKDIIEGIESFFGTHRRFELKGCKNNITVIDDYAHHPTEISATLDAAKKYPHNKMFCVFQPHTYSRTLTLFDDFTKCFDNADEIILADIYAAREKDTGIINSNMLGDKLRERGLKCTNFHKFDDIKNYLIENAKDGDLILTVGAGDIYKVGEMYINL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_AERPE
Sequence: MAMYPRELKWGVAHIYSSFNNTHVHITDLTGAETVARVTGGMVVKADREKPSPYAAMIAASRAAQKAMERGIAAIHIKVRAPGGHGPKTPGPGAQAAIRALARAGFIIGRIEDVTPIPHDTTRRPGGRRGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PEPCK_PROFF
Sequence: MSVVERRQINAAINLRLSLLGLPHPDSNAESPDAILVEPLLARQRELSRRLKDRLSAPDLRIQRFLDDYLADCDEHPQLPRTTLVLDEPGLARGLSLPVDGDEFHSDIVASYRLVNGVLHNPKHDRRTTAGVFHISTGGLPIPQDKVEVDKNVYARILARAFQAPDEELALPYTANLPEQAHCWASLLMRPTVLPAVPGRTTEKSYEVHFIVPGGLMCNLDFVEGIFGNAGDPYLPENDASLDPDSWTGHTGCVILAPHLTTMTKKSLGMPHYDDATERQRRDGQCWRHEDDLYNDGKAFKVCARDERGVIVTVIADNYFGYCKKEVKTQISYSANLLGGAEEEHSGGAEVYPAWNLNQDFTDRTPDDFTLADVISTNRELLDVRPEGYAVYKPEPNIVFIPEHSHYSMRTQTISWTAHGAEQTIKLLAGKHYLSPDGYRIHAKHREMDATQWHLIGTSSRAVTCHKPATVSGGGKSEISKSISDAFVFGNAFSHDIDSAMDQVQALFDTDFTNRFADASRNGTDHRPVLSIDRSLGSVIKLLTPSIQYNDEYNAFLEGIEPDVKELAFTVKRYYLPEWGEDWRSHFTVGIMNGRHGNMVRLDGKKIITNMLRVGFREDGSWRLFTLRPDYSPAVKVQTEDDITASTVTPPWEDAEGLPRKYVTNCEHLLFQRPDDAIHRGYDKQAEFDLASGTDTFISNFEPLTHEQARDLLTDVQAYSEFTKPVRKLIERVAAMPDDQSPEFWVCSDDPRHLPDGGRSKNPRYLQVRPTDSNPELTTVADVAGKLARKLPLAGHAPQPIDVVAAGRRNNPPEDKVPALCAYNPLHYMELPELFMEYISSMTGKSPSTTGAGSEGALTKGPFNALPAVYDLNAALLSYALTDYDGWLSSAGYIGPNARVDHDISMLIPELFSHMGPNDRNTKRLISEGYLEKMQDFDFDGHRVLASRLGYRINDRFVTHYFGRIFLHPDVVFSEEMLRPELQDEKIFADSIDVIVKTHQRVAQMYFDDGTVSLACPPIRALLEIMAHGASAEGWTLDSPEFRKLFERESVLASDWYAQRLDAKQAEDVKQAEEGVERLKEYIGRSDSGSVTGRLHLADRLRELEAQLTYERSPEYRQSLVGTLGRQPRFV
What is the function of this protein?
Inorganic pyrophosphate (PPi)-dependent phosphoenolpyruvate carboxykinase, which regulates the carbon flow of the central metabolism by fixing CO(2) to phosphoenolpyruvate to produce oxaloacetate.  Can also produce pyruvate and diphosphate from phosphoenolpyruvate and phosphate.
What are the official names of this protein?
PPi-type phosphoenolpyruvate carboxykinase, PPi-PEPCK, PfPEPCK, Diphosphate-dependent phosphoenolpyruvate carboxykinase, PEP carboxyphosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the PPi-type phosphoenolpyruvate carboxykinase family.
Protein: GSTCD_DROPS
Sequence: MDQLYLEIEISTQNAETTIYTSVSSFLALYTYRYLNEPKNIQVNFVATKIESGKIALRSSQLRRELTDQHITCREAAKLPAIRDLRLPIYEKDGNTFIAGTCAVCRELIARQPNTELRKLLGFKESCLLAPSEASIWTRFCEVDVVDVVSRLHEGLLLKAVPDEVVRFEQHMNEPVRMHNIYKQAREQANQTENGAKIKRKHRVQIDGRTPKEQLLIEHRFAEGISFTIADLILYPLLRIVFQHCGQMLPHFPLTSTWFSEIDSFDGTCAKILGDLYVPQAASQGEELLSIPDCDATSLYKADPKRYKPRNRIYTSQAEVDLALAKLSELQLVFSTDSEHTYGQQTIDWQKIEPTHAKSSALPQERLERKRQQLENMANAVVSLAQPGDRIVDFCSGTGHLAILLALKLPLCTIIVMENKSFSLAQAQKRALELELSNCVFYQCNIDYFVGRFDIGASLHACGTATDIVLQQCRRSVAHFVCCPCCYGSLQPMPHISYPLSQRFQRVLSTNDYLYIAHTADQAHEMGTTNCKPETTLQGLQCMSIVDTDRKLQSEEAGYQVILTRLKPEQCTPKNHLLVGRFVKQN
What are the official names of this protein?
Glutathione S-transferase C-terminal domain-containing protein homolog.
What is the protein family that this protein belongs to?
Belongs to the GSTCD family.
Protein: ADHA_SYNY3
Sequence: MIKAYAALEANGKLQPFEYDPGALGANEVEIEVQYCGVCHSDLSMINNEWGISNYPLVPGHEVVGTVAAMGEGVNHVEVGDLVGLGWHSGYCMTCHSCLSGYHNLCATAESTIVGHYGGFGDRVRAKGVSVVKLPKGIDLASAGPLFCGGITVFSPMVELSLKPTAKVAVIGIGGLGHLAVQFLRAWGCEVTAFTSSARKQTEVLELGAHHILDSTNPEAIASAEGKFDYIISTVNLKLDWNLYISTLAPQGHFHFVGVVLEPLDLNLFPLLMGQRSVSASPVGSPATIATMLDFAVRHDIKPVVEQFSFDQINEAIAHLESGKAHYRVVLSHSKN
What is the function of this protein?
Active on a wide variety of primary alcohols and their corresponding aldehydes, but not against ketones nor secondary alcohols.  Active on aliphatic compounds up to 5 carbons in length and aromatic alcohols, less effective on branched-chain primary alcohols.  Prefers NADPH to NADH.  Its catalytic efficiency is greatest for aldehydes, suggesting the reduction of aromatic and medium-chain aliphatic aldehydes is its in vivo activity (PubMed:19411329).  Plays a role in tolerance to internally produced ethanol (PubMed:28160048).
What are the official names of this protein?
Aldehyde reductase AdhA, Alcohol dehydrogenase AdhA.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.