PharMolix/UniProtQA huggingface dataset:
Protein: TBB_TOXGO
Sequence: MREIVHVQGGQCGNQIGAKFWEVISDEHGIDPTGTYCGDSDLQLERINVFYNEATGGRFVPRAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVVRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKVREEYPDRIMETFSVFPSPKVSDTVVEPYNATLSVHQLVENADEVQVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCCLRFPGQLNSDLRKLAVNLVPFPRLHFFLIGFAPLTSRGSQQYRALSVPELTQQMFDAKNMMCASDPRHGRYLTASAMFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNMKSSVCDIPPKGLKMSVTFVGNSTAIQEMFKRVSDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFDEEEGEMGAEEGA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LIPB_ANAMF
Sequence: MSLLGFPVEWRVSDGMVDYKAALDFMTSRVDGILEGRESEMVWLLEHPSVYTAGVSAKDGELLSENKFQVVRTTRGGKYSYHGPGQRVVYVMLHLGRRDKRDVRLYVRNLGLWVVGTLAEFGIDSHFDDDNTGVWVQYSRQAKKIAAFGIAIRRWVTYHGFSVNISTDLGCYSGIVPCGIAGSHVTSLQDLGVTVPFEEFDAVLQQKFDTIFLQ
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORN_SERP5
Sequence: MTGNENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVIAVHQSDEQLGLMDDWNVRTHTGSGLVERVKASQYDDHAAELATIAFLQQWVPAGKSPICGNSVGQDRRFLFRYMPELEAYFHYRYLDVSTLKELARRWKPEILSGFKKQGTHQAMDDIRESVGELAYYREHFIQL
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_THEPX
Sequence: MLDVKRIRNNPEAVRIAIELKGEKADIDRFLELDEKRRQMLVELETLKNRRNVESDNIAKLKREGKDASDLIAEMKELSDKIKEMEQEVKEVEEELERILWTIPNIPHESVPIGDSDEDNVEIRRWGEPRKFDFEPKPHWEIGQELDILDFEAAARVTGSRFTFYKGLGARLERALINFMLDLHIEKHGYTEVFPPFMVHRRSMFGTGQLPKFEEDAFKVYGTDYFLIPTAEVPVTNMYRDTIIDGDKLPIYHCAYSACFRQEAGSAGRDTRGLIRQHQFNKVELVKFTEPDKSYEELEKMTRDAEEVLQALGLPYRVVVICTGDLGFTASKKYDIEVWMPSYGRYVEISSCSNCEDFQARRANIKYRPKDGGKAQYVHTLNGSGVAVGRTFAAILENYQQEDGSVVIPEVLRPYMKVDVIKK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y886_STRZJ
Sequence: MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEVSRFLEEHASFSFNLGDFDAIWQEYLEH
What are the official names of this protein?
UPF0346 protein SPJ_0886.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: COBT_GEOSM
Sequence: MELLESALAKIQPVDEALLAQAQAKLDNKTKPPGSLGLLEEMARRFAAITGDLSPKMGKKVVFTFAGDHGIVEEGVSLYPKEVTPQMVLNFLRGGAGVNVLARHAGAEVRVVDVGVDYDFEPTEGLIIRKIAKGTRNFAKESAMTREEAVAAIEVGIALADRAKAEGISMVGTGEMGIGNTSPSSAIIAAFAGCSVREVTHRGTGIGDQALEHKIKVIQAGLDLNRPNPEDPLDVLAKVGGLEIAGIAGLVLGAAANRIPVVVDGFISTAGALIACELHPNVREYIFAAHNSVEIGHQMMLQRIGAKPILDLQLRLGEGTGAALAMGLIEASVKVLNEMATFEEAGVTS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: ALLS_SALPA
Sequence: MFDPETLRTFISVAETGSFSKAAERLCKTTATISYRIKLLEENTGVGLFFRTTRSVSLTAAGSHLLSQAKDWLAWLDSMPDELRQVNDGVERQVNIVVNNLLYSPQAVASLLSWLNARYPFTQFHFSRQIYMGVWDSLLYEGFSLAIGVTGTEPLANTFMLDPLGSVQWRFVMSADHPLAHVSGPLTEAQLRRFPAINIEDSARTLTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGFVPQPLCQTLIDKNELVSCTIPTMRPPSPLSLAWHKFGGGKAVEDIVKLFTQRQPEIAGFLSIFNTVRC
What is the function of this protein?
Positive regulator essential for the expression of allD operon.  Binds to the allD promoter (By similarity).
What are the official names of this protein?
HTH-type transcriptional activator AllS.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: NADE_STAA1
Sequence: MSKLQDVIVQEMKVKKRIDSAEEIMELKQFIKNYVQSHSFIKSLVLGISGGQDSTLVGKLVQMSVNELREEGIDCTFIAVKLPYGVQKDADEVDQALRFIEPDEIVTVNIKPAVDQSVQSLKEAGIVLTDFQKGNEKARERMKVQFSIASNRQGIVVGTDHSAENITGFYTKYGDGAADIAPIFGLNKRQGRQLLAYLGAPKELYEKTPTADLEDDKPQLPDEDALGVTYEAIDNYLEGKPVTPEEQKVIENHYIRNAHKRELAYTRYTWPKS
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: LEU1_YERPG
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDIMEVGFPVSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHIESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAITAGATTINIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQVEGTINGLGERAGNCSLEEVIMAIKVRHEMLGVHTNINHQEIYRTSQLVSKICNMPIPGNKAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPESIGLKEVQLNLTSRSGRAAVKHRMEEMGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEYYRLDYFSVQSGSSVMATASVKLVCGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSAKGQGKDALGQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLNNIWRAHQVEKEKQRLQQNNQEMV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: URE2_STAEQ
Sequence: MIPGEIIVKNTEIEVNKHHPETVIEVKNTGDRPIQVGSHFHFFEANKALEFDREKAYGKHLDIPAGAAVRFEPGDEKKVQLVEYSGRRKIYGFRGLVDGDIDEERVFRPNDSNQNAAVKNDAGEDNANKKGGK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_KORVE
Sequence: MSDPLLFVLLGPTGSGKTSLSIALAERFGGEIVNCDSVAVYRELDIGTAKPTHEERESVPHHLFDVLPPTEPMTAGEYARRAREVLKDIASRGKLPIVVGGTGLYLRALLDGLFAGPERSEELREHLRRREQERGPTYLHRILSRMDRVAAAKIHPNDAAKLIRAIEVCLAARKPMTELWQQGRDPLTGFRILRIGLDPDRPALYDRINRRAAEMFEQGLVEETQALLAKYGRIGGPLDSLGYRQAFELLDGKLTREQAVAAAQQGHRNYAKRQMTWFRREPEVRWLKGFGDDAAIVGEAMQIIKTS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SYS_BACC7
Sequence: MLDIKFLRTNFEEVKAKLQHRGEDLTDFGRFEELDTRRRELLVQTEELKSKRNEVSQQISVLKREKKDAEALILEMREVGEKVKDLDNELRTVEEDLERLMLSIPNIPHESAPVGETEDDNVVARTWGEVKEFAFEPKPHWDLATDLGILDFERAGKVTGSRFVFYKGAGARLERALISFMLDLHTDEHGYEEVLPPYMVNRASMTGTGQLPKFEEDAFRIESEDYFLIPTAEVPVTNMHRDEILNKDQLPIRYAAFSSCFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYEELEKLTNDAERVLQLLELPYRVMSMCTGDLGFTAAKKYDIEVWIPSYGTYREISSCSNFEAFQARRANIRFRREPNGKPEHVHTLNGSGLAIGRTVAAILENYQQEDGTIIIPEVLRPYMGGKTVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDL64_ARATH
Sequence: MSLLVFLCQIIVLSVLFFSEVCLAGKKIPANFVFGDSLVDAGNNNYLATLSKANYVPNGIDFGSPTGRFTNGRTIVDIVYQALGSDELTPPYLAPTTSGSLILNGVNYASGGSGILNSTGKLFGERINVDAQLDNFATTRQDIISWIGESEAAKLFRSAIFSVTTGSNDLINNYFTPVISTLQRKVVAPEVFVDTMISKFRLQLTRLYQLGARKIVVINIGPIGCIPFERESDPAAGNNCLAEPNEVAQMYNLKLKTLVEELNKNLQGSRFVYGDVFRIVDDIIQNYSSYGFESEKIPCCSLVGKVGGLIPCGPPSKVCMDRSKYVFWDPYHPTEAANIIIARRLLSGDTSDIYPINIRQLANLKINA
What are the official names of this protein?
GDSL esterase/lipase At4g16230, Extracellular lipase At4g16230.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBC4_ARATH
Sequence: MSSPSKRREMDMMKLMMSDYKVETINDGMQEFYVEFNGPKDSLYQGGVWKIRVELPDAYPYKSPSVGFITKIYHPNVDELSGSVCLDVINQTWSPMFDLVNVFETFLPQLLLYPNPSDPLNGEAAALMMRDRPAYEQRVKEYCEKYAKPGEGSEDKSSDEELSEEEYGSDNEDDDDDDVAIAGKPDP
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 4, E2 ubiquitin-conjugating enzyme 4, Ubiquitin carrier protein 4, Ubiquitin-conjugating enzyme E2-21 kDa 1, Ubiquitin-protein ligase 4.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: SDHF2_YEAST
Sequence: MHNMFPALTKTLSLQGYKIINSQTGSAAWSCGRRWFSSDKDDHDDVVTRIKIAPIKRTNEPLDKKRARLIYQSRKRGILETDLLLSGFAAKYLKKMNEEELEEYDSLLNELDWDIYYWATKNFKTSPLPDKWANSKLLKQLQEFSENKEKEILSMPDLSKYQ
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDH1 of the SDH catalytic dimer.  It is unclear whether it participates in the chemistry of FAD attachment (enzymatic function) or acts as a chaperone that maintains SDH1 in a conformation that is susceptible to autocatalytic FAD attachment (PubMed:19628817).  Does not bind FAD or FADH(2) in vitro (PubMed:23062074).  Involved in sporulation (PubMed:12432101).  Required for the full activation of the early meiotic inducer IME1 (PubMed:12586695).
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
Protein: RR18_ORYSA
Sequence: MYTSKQPFHKSKQTFHKSKQTFRKSKQTFRKFKQPFRKPKQPFRRRPRIGPGDRIDYRNMSLINRFISEQGKILSRRINRLTLKQQRLITLAIKQARILSFLPFRNYENEKQFQAQSISIITGPRPRKNRHIPPLTQKFNSNRNLRNSNQTLRNNNRNLSSDC
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RIP1_PHYAM
Sequence: MKSMLVVTISIWLILAPTSTWAVNTIIYNVGSTTISKYATFLNDLRNEAKDPSLKCYGIPMLPNTNTNPKYVLVELQGSNKKTITLMLRRNNLYVMGYSDPFETNKCRYHIFNDISGTERQDVETTLCPNANSRVSKNINFDSRYPTLESKAGVKSRSQVQLGIQILDSNIGKISGVMSFTEKTEAEFLLVAIQMVSEAARFKYIENQVKTNFNRAFNPNPKVLNLQETWGKISTAIHDAKNGVLPKPLELVDASGAKWIVLRVDEIKPDVALLNYVGGSCQTTYNQNAMFPQLIMSTYYNYMVNLGDLFEGF
What is the function of this protein?
Possesses antiviral potency.  Inhibits viral infection of plants (tobacco mosaic virus) (PubMed:10403789).  Inhibits protein synthesis (PubMed:2930487, PubMed:6091760, PubMed:2248976, PubMed:10403789, PubMed:10595542).  Releases both adenine and guanine from Escherichia coli rRNA in vitro.  Activity on guanine is 20 times slower than that on adenine (PubMed:10595542).
What are the official names of this protein?
Antiviral protein I, PAP-C, PAP-I, PAP-R, Ribosome-inactivating protein, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: RL14_GEOUR
Sequence: MIQMQTILDVADNSGAKKLFCIKVLGGSKRKYAGIGDIIVASVKEAIPNSKVKKGDVVKAVVVRTAKEIGRPDGSYIRFDGNSGVVINNQKEPVGTRIFGPVARELRAKKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: UPPP_POLNA
Sequence: MDIALLIKAAIMGIVEGLTEFLPISSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVILVYWQKIRSTLIALPNEKQAQQFALNVLVAFVPAVVLGLLFGKAIKAHLFTPVVVASAFIVGGFIILWAEKRQQRNPATIRIHDVESMSTMDALKVGLVQCLAMIPGTSRSGSTIIGGMLLGLSRKAATDFSFYLAIPTLIGAGAYSLFKDRALLSMADAPMFGVGLLFSFLSAWLCIRWLLRYIASHDFVPFAWYRIAFGIVVLATAWSGVVTWAE
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL9_BRUA1
Sequence: MEVILLERIGRLGQMGDTVKVKDGYARNFLLPQGKALRANEANKKKFEGQRAQLEAQNLERKNEAQAVADKLNGESFIVVRSAGETGQLYGSVSTRDIAEIITANGFTLHRNQVELNHPIKTIGLHEVSVSLHPEVQVKVMVNIARSTEEAERQAKGEDLTSIEAIYGIEEQPLSEEVFDDEDEAEDQA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: Y397_MYCGE
Sequence: MLVFLILLPFLLLVIFGAYLLVCLFVRQNNLLLKKTKQLYNNLKLSNFNCVISPFQLLRNEKQALEQSIKVLKQFQIKFDNEINSAFEQLTVYSKPNNIYRFIWFNRNIKLLNKNLQHLYTKQQEYINLTKNAIVYFNNSYDCLVFYRQAFCFLNQFINNFLIEKYDSLFYLNVLNRISLLFKEIENCIQAKDVEKQIAFLNKLHNILSQTIITANRQYMFDIKLSYLTHHFKVLIQKVKQMELMKNKVINSQDLLKLHELINNITIKLKDCTNFLNNLNLMLCERNMDEVQEAISWLFQAVSSKEKSINLVVENIDDFRNQIQQYEKKNELLKTTIKAIELVFQNETDVHDLIIELNENCDLITKNINNLNHQSLAQNQINYEKLFYLMSQTNQALEKLKNSLTDLLNLAVNKFDDYRFFVYTLDDFRFKFFQIENLISDQDLKVPAKTLQVINKSKLELDNIFTEANNNYLGTFNLFSEKIDLLQIQLTEVICDVVSLVNLRLMCKQAFLFANKYRQKSSHIDRSLEQLTKLYNRQNYPDTLEGLINLLTKIKTNTKQDYLELN
What are the official names of this protein?
Uncharacterized protein MG397.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RF1_MYXXA
Sequence: MIDKLEDVERRFERLTADLSNPDVLADSARLQKVSKERAGLEKLVEAFRTYRKVLADLSEVEAWLGSSDADEKAFARESLPGLKEQRDELEASLKILLLPKDPNDEKNVILEIRAGAGGDEAALFAEEVMQMYLRYADRRGWKADILDMSPGNAGGVKDATVTLSGDAVFSSMKYESGVHRVQRVPATETQGRIHTSTITVSVMPEAEDVDVQVNPADIEMQVMRSTGSGGQSVNTTDSAVRLIHHPTGIVVKCQQEKSQLKNRTMAMRMLRAKLYDIEQERIRNERDSARRAQVGTGDRSEKIRTYNFPQDRLTDHRIGLTVHNLPGVMAGDVEDVITACRTFYQAEALKAQTAGGPKPSA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFAB_DICDI
Sequence: MKLLNSLILLVLTCLVSSINTQFISIQKYDFSGNCKNSSDSASSFEASSESAAICMQNDLLSGIVTNEGVCLIFNEIPTTFLISSNGDYVVILLEIEQLKLVNVLLSVLMITTEVHIYFQLKHLSITHLIPTLKYLTMANVMDNGKLVLTIFNITLSINVMLHMKLKLIPFL
What are the official names of this protein?
Counting factor-associated protein B.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC_NITHX
Sequence: MSKPTTLYDKIWNDHLVHEAEDGTCLIYIDRHLVHEVTSPQAFEGLRVAGRKVHAPEKTLAVVDHNVPTTDRTKPNPDPESAEQIATLAQNAKDFGIEYYNEFDKRQGIVHVIGPEQGFTLPGTTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAKNMRAVVYGTLPDGVTAKDIILAIIGEIGTAGGTGYVLEYAGEAIRALTMEGRMTVCNMSIEGGARAGLVAPDEKAYEFLKGRPKAPRGADWDAAMRYWETLRSDDGAHFDHEIRLDAARLPPIVTWGTSPEDVISVTGKVPNPADIADEAKRLSKERALHYMGLAAGTRITDITLDRVFIGSCTNGRIEDLRAAAKIADGRTVNGNVNAMVVPGSGLVKEQAEAEGLDKIFIKAGFEWREPGCSMCLAMNPDKLKPEERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGHFVDVREWH
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RM02_ORYSA
Sequence: MRQSIKGRALRHFTLSTGKSAGRNSSGRITVFHRGGGSKRLQRKIDLKRSTSSIGIVERIEYDPNRSSRIALVRWIEGVLPGRQRKFKTIEEFALPRKILESTTATIFCLFSFSSLSSPLAQGETASLSFGSSLGFPRIAVAGAKPAFFAERMREKKIGKKTFSLCEIRKWRTHCVLWAHRIKRKAALSWQSLRQQKTLELVGAAEHNESKLKADQGSLLPRQVLAYALCSGRPSYLHASRSFYKALLPVEASRFGSLPAKPPIGEGPKDGAYKVDRAPVTYILASHQLEAGNMVINCDCSKPSKSGFLRPAQNAHTYLRFQELGRTVNKGRVEGGSQLAASWPRPPAYRHEILDLNSKVGNSIPLADIRMGTWVHDIECHPGQGAKLARAAGTYAKIIKEPASQCLVRLPSGVEKLIDSRCRATIGIVSNPNHGARKLRKAGQSRWSGRRPIVRGVAMNPVDHPHGGGEGRTKGGRPSVSPWGKPTKAGFRAGVGVGKRRI
What are the official names of this protein?
60S ribosomal protein L2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HIF1A_ONCMY
Sequence: MDTGVVPEKKSRVSSDRRKEKSRDAARCRRGKESEVFYELAQELPLPHSVTSNLDKASIMRLAISYLHMRNLLSTDNEEEQEEREMDSQLNGSYLKAIEGFLMVLSEDGDMIYLSENVNKCLGLAQIDLTGLSVFEYTHPCDHEELREMLVHRTGTSKKSKEPNTERSFFLRMKCTLTNRGRTVNVKSATWKVLHCSDHVRVHESPAEQIPGGHKEPSVPYLVLVCDPIPHPSNIEAPLDTKTFLSRHTLDMKFTYCDERITELMGYDPEDLLNRSVYEYYHALDSDHLMKTHHNLFAKGQVSTGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNYVLSGIEEEKMMLSLEQTEDMRPVKKELEEEESSEPEVSPVLLKEEKSPELDVIKLFTRAVETQPLSSLYDRLKEEPEALTLLAPAAGDTIISLDFSSPDSDILQKEVPLYKDVMLPSTSDKLALPLSLLPPSDQHLVPNTSVDTTEVSTGPDSSSTPGSHSFTEPDSPLDFCFPMESDINAEFKLDMVETLFAINPEPKTPFTLQAMEDLDLEMLAPYIPMDDDFQLRTLSPEEPLSCGPAQPLECSSLCSSVRLTQEVHSYPGSPFNAPGSLTASPALAASPALAAPEPADSPCPASLLTKTVPQMDREISLRSLASQNAQRKRKMSLSQAVGIGGLLQDHPGPGKKLKVSELSHADAPFNRTILLLPTDLASRLLGISSEGSGSPFTLPQLTRYDCEVNAPVGGRQLLLQGEELLSALDQVN
What is the function of this protein?
Functions as a master transcriptional regulator of the adaptive response to hypoxia.  Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia.  Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease.
What are the official names of this protein?
Hypoxia-inducible factor 1-alpha, HIF-1-alpha, HIF1-alpha.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Note=Cytoplasmic in normoxia, nuclear translocation in response to hypoxia.
Protein: CAV1_RHIFE
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKTMADEMNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSAVFGIPMALIWGIYFAIVSFLHIWVVVPYIKSFLIEIQCISRVYSIYIHTFCDPLFEAFGKVFSNIRINTQKEI
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: P5CR2_MACFA
Sequence: MSVGIIGAGQLAYALARGFTAAGIVSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETVKHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTNTPVVVREGATVYAMGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAFMALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTLTPSSPGKLLTRSLALGGKKD
What is the function of this protein?
Housekeeping enzyme that catalyzes the last step in proline biosynthesis.  In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+).  Can utilize both NAD and NADP.  Has higher affinity for NADP, but higher catalytic efficiency with NADH (By similarity).  Involved in cellular response to oxidative stress (By similarity).
What are the official names of this protein?
Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: RLMC_EDWI9
Sequence: MHCVQYQAGRCHSCQWLSIPYSRQLEDKQRHLSALLSGHSVAQWLSAQPSAELAMRNKAKMVVSGSVERPLLGMLQRDGSGVDLCDCPLYPDSFAVVFAALKSFIPRAGLTPYSVARRRGELKYLLLTESRLNGEMMLRFVLRSETKLAQLRQALPWLQAQLPQLAVISVNIQPVHMAILEGEREIFLTSQQVLSESFNGVPLYIRPQSFFQTNPAVAQALYAQARDWVQALGVTEMWDLFCGVGGFGLHCATPEMTLTGIEISAGAIACARRSAAQLGLTKVSFAALDSGAFADAHSAVPQLVLVNPPRRGIGAALCDYMNRMAPPYILYSSCNAQSMVQDIERLADYRIEKVRLFDMFPHTAHYEVLTLLVRASA
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.