PharMolix/UniProtQA huggingface dataset:
Protein: TSAC_LARHH
Sequence: MFRALPAAQRRAARAHLRAGGVLAYATESCFGLGCLPGNARGLRTILRLKGRPNHKGMIVVGRRFADLRRLVRPVDAAGQARLMSRWPGPTTFLLPADRRVLPLLRGRHRTLAVRVSAHHGVAMLTRDLGPLVSTSANFAGKVSLKNAAACRRTFGQEVMVLPGRTGRARRPSAIIDFASGRVLR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGLT1_RAT
Sequence: MERLSGCRLRPWMLLLLLFPVQGRQKDSGSKWKVFIDQINRALENYEPCSSQNCSCYHGVIEEDLTPFRGGISRKMMAEVVRRRLGTHYQIIKHRLFREDDCMFPSRCSGVEHFILEVIRRLPDMEMVINVRDYPQVPKWMEPTIPVFSFSKTSEYHDIMYPAWTFWEGGPAVWPLYPTGLGRWDLFREDLLRSAAQWPWEKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLIDHCKYKYLFNFRGVAASFRFKHLFLCGSLVFHVGDEWVEFFYPQLKPWVHYIPVKTDLSDVQELLQFVKANDDLAQEIAKRGSQFIINHLQMDDITCYWENLLTEYSKFLSYNVTRRKDYYQIIPRRLKTEL
What is the function of this protein?
Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C.  Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 (By similarity).  Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development (By similarity).  Notch glucosylation does not affect Notch ligand binding (By similarity).  Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (By similarity).
What are the official names of this protein?
Protein O-glucosyltransferase 1, O-glucosyltransferase Rumi homolog, Protein O-xylosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 90 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: NTF3_ERYJO
Sequence: IQSTSMDQGILTEDSMNSFIRTLIQAGIWKNKVPKQTARTKDGTQTTVKKTEAEADAMVSKDTRLSFQPIVSVDAELLRQQRRFSSPRVLLSENTPLEPPPLYLTEEPTVLNRTSRRKREGKSHRGEYSVCDSESRWVTDKSSAVDIRGHQVTVLGEIRMGPS
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: SH3G3_DROER
Sequence: MAFAGLKKQINKANQYMTEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTARAKMAAVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKYSLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAKDDEIRGAEDKFGESLQLAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQETLQEKRSEAESRPRNEFVPKTLLDLNLDGGGGGLNEDGTPSHISSSASPLPSPMRSPAKSMAVTPQRQQQPCCQALYDFEPENPGELAFKENDIITLLNRVDDNWFEGAVNGRTGYFPQSYVQVQVPLPNGN
What is the function of this protein?
Required presynaptically at the neuromuscular junction.  Implicated in synaptic vesicle endocytosis.
What are the official names of this protein?
Endophilin-A, SH3 domain-containing GRB2-like protein.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Associated with internal membranes. Expressed presynaptically at NMJs.
Protein: POTA_VIBPA
Sequence: MGEIQTLNAKQQAGKPVIRLSGISKSFDGKEIIGNLNLDVNHGEFLTILGPSGCGKTTVLRMIAGFETADNGQIVLDDQDVTQVPAEHRHVNTVFQSYALFPHMTVFDNVAFGLRMQKTPAAEIEPRVMEALRMVRLEKMAQRKPHQLSGGQQQRIAIARAVVNKPKVLLLDESLSALDYKLRKQMQIELKQLQRQLGITFIFVTHDQEEALSMSDRIIVMRDGVIEQDGSPREIYEEPKNLFVARFIGEINVFNATMLERIDEKRIRAEIEGVESVVYYDKEAQAGDKLQVLLRPEDLRIEEIKESEEKGIVGHVTERTYKGMTLDSVVQLDSGMRVMVSEFFNEDDPDVDHSLGQKVAITWVESWEVVLNDKQED
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACP_GLUOX
Sequence: MSDIADKVKKIVVEHLGVDESKVTPDASFIDDLGADSLDTVELVMAFEEAFSVEIPEDAAEKIATVKDAIDYIEKQKAA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUB9_PANTR
Sequence: MAFLASGPYLTHQQKVLRLYKRALRHLESWCVQRDKYRYFACLMRARFEEHKNEKDMAKATQLLKEAEEEFWYRQHPQPYIFPDSPGGTSYERYDCYKVPEWCLDDWHPSEKAMYPDYFAKREKWKKLRRESWEREVKQLQEETPPGGPLTEALPPARKEGDLPPLWWYIVTRPRERPM
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9, Complex I-B22, CI-B22, NADH-ubiquinone oxidoreductase B22 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: BETA_RHIL3
Sequence: MQADFVIIGSGSAGSALAYRLSEGGKNSVIVIEAGGSDFGPFIQMPAALAWPMSMKRYNWGYLSEPEANLNNRRITAPRGKVIGGSSSINGMVYVRGHAEDFNRWEELGASGWAYADVLPYFKRMEHSHGGEEGWRGTDGPLHVQRGGFTNPLFQAFVEAGKQAGFETTEDYNGSKQEGFGLMEQTIFGGRRWSAANAYLKPALKRDNVKIVYGLAQRIVIEDGRATGVEIERNGRIEVVKANREVIVSASSFNSPKLLMLSGIGPGQHLQDMGIAVKADRPGVGANLQDHMEFYFQQVSTKPVSLYSWLPWFWQGVAGAQWLLSRGGLGASNQFEACAFLRSAPGLKQPDIQYHFLPVAISYDGKAAAKSHGFQVHVGYNLSKSRGSVSLRSADPKADPVLRFNYMSHAEDWEKFRHCVRLTREIFGQSAFHDYRGPEIQPGEGVQSDEEIDAFLREHLESAYHPCGTCRMGAKDDPMAVVDPQTRVIGIDGLRVADSSIFPHVTYGNLNGPSIMTGEKAADHILGKQPLARSNQEPWINPRAAVSDR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: TAL_PSESM
Sequence: MTSKLDQLKKFTTVVADTGDFGAIKSLKPQDATTNPSLLLKAASSESNDQMLADAFSGAKGDIGLACDRFAVAIGQEILKVVPGRVSTEVDARLSFDTDALIERSERIIGLYDTAGISRDRVLIKLAATWEGIRAAEKLEKDGIQTNLTLLFSFAQAVACAEAGVFLISPFVGRIYDWYKKSSGTDYVGADDPGVQSVTRIYNYYKANDFKTVVMGASFRNLNQIEQLAGCDRLTISTELLKQLAEDTGTLEQKLAPGNAGEARQSLTESQFRWASNEDAMATEKLAEGIRQFARDQEKLEALLSAKKS
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_LEGPA
Sequence: MKRIKSGDEVIVIAGKSKGHIGKVLRVVDDAVVVEGGNLIKKHIKPNPQKPENKGGIIAREAPLHVSNVAHYNPVTKKADKVGFKYLESNGVSKKVRYYKSNNEIIDRI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MPI_RAT
Sequence: MANPRVFPLSCVVQQYAWGKVGSKSEVACLLACSDPLTQISEDKPYAELWMGAHPRGDAKILDNRISQKTLGQWIAENQNSLGQKVKDTFNGKLPFLFKVLSVETALSIQAHPNKELAEKLHLQAPEHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQSLIGEDATAQLKKSMNEGSGAMASALKNCFSHLMKSEKKVVVEQLNLLVKRISQQISNGNSMDDICGELLLQLHQQYPGDIGCFAIYLLNLITLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVSTLCEMLDYTPSPSKDRLFAPTLSQDDPYLSIYDPPVPDFTVMKIEVPGSVTEYKVLTLDSASILLLVQGTVTAIIPSVQGEIPLSRGGVLFIGANETVLLKLTVPKNLLIFRACCLL
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
What are the official names of this protein?
Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPH_OCEIH
Sequence: MMDANEIIQFISDSKKSTPVKVYVKGELDKLSASNTIKTFVDSKSGTIFGEWKDIQAYLEENKSLIEDYIIENDRRNSAIPMLDLKNINARIEPGAIIRDQVEIGDGAVIMMGASINIGSVIGEGTMIDMNAVLGGRATVGKNCHIGAGSVLAGVIEPPSAKPVIVEDDVVIGANVVILEGITVGKGSIVAAGSIVTKDVAPNTLVGGTPAKVLKEIDEQTKSKTEIKQELRKLDN
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: IF3_CAMJE
Sequence: MSKEKEVLLNEEIRADEIRCVGDDGKVYGIISSDEALEIANRLGLDLVMIAADAKPPVCKIMDYGKFRYQQEKKQKEAKKKQKVIDIKEIKLSVKIAQNDINYKVKHALEFLEQGKHVRFRVFLKGREMATPEAGVALLEKIWTMIENEANRDKEPNFEGRYVNMLVTPKKA
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_BRUSU
Sequence: MRVLGIETSCDETAAAIVERDDMGEGRILSNVVLSQIAEHEPYGGVVPEIAARAHVEALDRLVDRALNDAGLKLYEVDAVAATAGPGLIGGLIVGLMTAKALAMAAQKPFYAVNHLEGHALTARLTDGLPFPYLLLLVSGGHTQMVLVRGIGDYERLGTTIDDALGEAFDKTAKLLGLPYPGGPAVERMALQGDQKRFALPRPLKGEARLDFSFSGLKTAVRQTATELVPLTDQDVTDICASFQAAVADTLSDRVGRSLERFKTEFPDCATPSLVVAGGVAANKTLRAALENLCTRHGFAFIAPPLNLCTDNAAMIAWAGAERAATQAPDSLDIAPRSRWPLDEKSAPVFGTGRRGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_FRACC
Sequence: MPALRSRTTTHGRNMAGARALWRATGMTDDDFGKPIVAVANSFTEFVPGHVHLRNLGSLVAGAVAEAGGVAREFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADALVCISNCDKITPGMLLAALRLNIPTVFVSGGAMESGNAVISGGTARSRLDLITAMSAAVNPDVSDGDLSTIERSACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSTLATAAARRELFVEAGRLVVDLARRYYEKDDEAVLPRSIATAAAFRNAFAVDVAMGGSTNTVLHLLAAAVEAGVDVTLADIDQISRTVPCLCKVAPSSTRYYMEDVHRAGGIPAILGELDRAGLLDPDPHTVHSASLREFLDRWDVRGPSPSPDAIELFHAAPGGVRTIEPFSSTNRWDTLDTDARDGCIRSVEHAYSAEGGLAVLFGNLAVEGAVVKTAGVDEGQWTFRGPALVVESQEEAVDAILTGRVKAGNVIIVRYEGPRGGPGMQEMLYPTAFLKGRGLGPKCALITDGRFSGGSSGLSIGHVSPEAAHGGTIALVRDGDIIEIDIPARRLELVVSDEELASRRAALEAAGGYRPTGRERPVSMALRAYAAMATSASTGAARDVGLLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: NUOD_RICPR
Sequence: MTNKTITLNLGPQHPATHGVLRLILEMDGEVVNNADPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEHAFALAVESLLECSVPRRAQFIRVLFSELTRILNHTLNIGSQALDIGATTPLLWLFEEREKIMEFYERVSGSRMHSNYFRPGGVAEDLPENLLEDINKFIEQFPSKLNDIENLLNENRLWKQRLVDIGVVSQKDAMDWGFSGPMLRGSGIAWDLRKSNPYDVYDEMDFEVPIGKNGDCYDRYLVRILEMYESIKIIKQCIVKMPKGQVKTDDPKLTPPTRGKMKESMEAMIHHFKLYTEGYDVPIGETYKAVEAPKGEFGVYLYSQGGNKPYRCRIKAPGFAHLQGLNFMSKGHLIADVITIIATLDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LOLA_PSEMY
Sequence: MRVIRLLMLAALSFTLLTAQADEEAATKRLTELLSQAQTISARFSQLTLDASGTQLQETAGQLVLKRPGLFRWHTDEPMEQLLVSNGQKVWLYDPDLEQVTIQSLDQRLTHTPALLLSGDVSQIRENFEIDYKEGGSVVDFILKPKAKDSLFDSLRLSFRNRMLNDMQLIDSIGQRTNILFLNVKMNEPVEDHLFTFDIPEGADVIQE
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYI_MACCJ
Sequence: MDYKDTLLMPKTDFPMRGGLPNKEPQIQAQWDEKKLYEKILKKNEGRTPYILHDGPPYANGQIHMGHALNKIIKDMIMRYKAMNGYYAPYVPGWDTHGLPIETALTKKGVDRKSMSEAEFRELCRAYALEQIELQKADFKRLGVNGDWENPYITLQEKFEAEQIRLFGDMAAKGYIYKGKKPVYWSPSSESSLAEAEIEYQDKVSPSIYVAFDVLDGKGLVDDDVKFVIWTTTPWTLPANVAIALNKDLDYVQVRVNDTSYIVAQALLDNVCDAVGWDKEGVQIEKTFKGADLEFVKARHPFIDRESLIILGDHVTTDAGTGCVHTAPGHGEDDFIVGQKYELDVISPVDGKGVYTSEAGEFEGMYYDKANKVITEKLEASGHLLKLDFFKHSYPHDWRTKKPVIFRATPQWFASINKVRQDILNAIEETEFKVEWGKTRIYNMIRDRGDWVISRQRVWGVPLPVFYAENGDIIMDKAVIEHVATLVEKHGTNVWYEREATDLLPEGYTHPGSPNGVFTKEKDIMDVWFDSGSSHRGVLEARPELSFPADLYFEGSDQYRGWFNSSITTAVATRGKSPYKKLLSHGFVMDGQGRKMSKSLGNTVLPEKVVKQMGADIIRLWVMSVDYLADVRISDDILKQVSEVYRKIRNTFKFLLGNVNDFNPATDAVPYAELVEIDQFMLNKLYTFVNNAHKHYDNNDYLFMYQELQNFINVELSNFYLDYGKDILYIEAQDSHVRRSMQTVVYEVLTSLTKVLAPIIPHTADEIWSHTPHVTEESVHLADMPEVQSVDTALIGKWNHFLEIRDDVLKAIEETRNDKVIGKSLEAAVYIQAKNEEDQALLKSFDNLHQLFITSYAEVVDEPQGTDYNLSNVLVKHAEGEKCERCWNYSTVLTEESHAHPHVCPRCLSVLESK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_VIBPA
Sequence: MAKKVEAYIKLQVAAGAANPSPPVGPALGQHGVNIMEFCKAFNAKTESLEKGLPTPVVITVYSDRSFTFVTKTPPAAVLLKKAAGVKSGSGRPNTEKVGTVTDAQIQEIAETKAADMTGADIEAMKRSIAGTARSMGLVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NAMA_GEOTN
Sequence: MNTVLFSPYTTRGLTLKNRIVMSPMCMYSCDTKDGTVRTWHKIHYPARAIGQVGLIIVEATGVTPQGRISEHDLGIWDDDHIHGLHELVGLVKEHGAAIGIQLAHAGRKSEVPGEIIAPSAIPFNESSPTPKEMTKADIEKTVQAFQDGARRAKKAGFDVIEIHAAHGYLINEFLSPLSNRRQDEYGGSPENRYHFLGEVIDAVREVWDGPLFVRISASDYHPDGLTVKDYVPYVKRMKEQGVDLVDVSSGAVVPARIDVYPGYQVPFAEFIRREAGIPTGAVGLITSGWQAEEVLHNGRADLVFLGRELLRNPYWPYAAAKELGVKIEAPVQYERGWRF
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: NRDR_LACLA
Sequence: MRCPKCSSEESKVVDSRQAEDAIRRRRVCESCGFRFTTFERIEEMPLLVIKKDDKREPFNREKIVRGLVRSAYKRPVSSEDIETTVANVERKIRQLDSNEVESDVIGEFVMQELAELDDITYIRFASVYRSFKDVSELEELLKNITKK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SNAG_MOUSE
Sequence: MAAQKINEGLEHLAKAEKYLKTGFLKWKPDYDSAASEYGKAAVAFKNAKQFEQAKDACLREAVAHENNRALFHAAKAYEQAGMMLKEMQKLPEAVQLIEKASMMYLENGTPDTAAMALERAGKLIENVDPEKAVQLYQQTANVFENEERLRQAVELLGKASRLLVRGRRFDEAALSIQKEKNIYKEIENYPTCYKKTIAQVLVHLHRNDYVAAERCVRESYSIPGFNGSEDCAALEQLLEGYDQQDQDQVSEVCNSPLFKYMDNDYAKLGLSLVVPGGGIKKKSPATPQAKPDGAAGMAAEEEEDEYSGGLC
What is the function of this protein?
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
What are the official names of this protein?
Gamma-soluble NSF attachment protein, SNAP-gamma, N-ethylmaleimide-sensitive factor attachment protein gamma.
What is the protein family that this protein belongs to?
Belongs to the SNAP family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Golgi apparatus.
Protein: KAD_STRSY
Sequence: MNLLIMGLPGAGKGTQAAKIVEKFNVAHISTGDMFRAAMANQTEMGILAKSYIDKGDLVPDEVTNGIVKERLVQDDIKEKGFLLDGYPRTIEQAHALDENLADLGIELQGVINIEIDPSKLVERLSGRIIHKETGETFHKVFNPPVGDYKEEDFYQREDDKPESVKRRLEVNIAQGQPIIDHYRAKGLVHDIEGDQDIDLVFQAIDTVLSKLQ
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB1F2_I02A1
Sequence: MEQEQDTPWTRSIEHINTQRRGNGQQTPKLEHPNSIQLMDHYPRITSRADMHKQIVCWKQWLSSKNPTQGSLKTHVLKRWKLFSKQEWTN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: RBFA_RHIME
Sequence: MAKSTSSAPSQRMLRVGEQVRAAITQVLQRGEVLDPLIENTVISISEVRMSPDLKIATAYVTPLGVADHAAVIEALNKHAKFIRGRLGPQLRQMKYMPDVRFRDDTSFDNYQKIDSLLRSPEVSRDLDRDADDEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF019_IIV6
Sequence: MKIGYIYAIENNLNDEVYIGSTLRTIEERFSEHKASARRRPTCTFHKFMSLHGIEHFKIIELKKIEVNSFFELQALEESYIRDYGSLNTINGVNKAAVHTRNEILVKRKIYSKECVKLPPLDEVIKIATKASLKKLEINEFIDLFIGEENKWNKMFDSDLSGIHISSLILNQLGYEGEFKNQQTCFKRFLKRNNIIIQEFSSSNPELKLYPSIQEEMKNMKTNVIANRKWLIANPRDLKKIIMKLNTKNGDAIREYYICMDELVQFYSQYSLSYDSNNN
What are the official names of this protein?
Uncharacterized protein 019R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 019R family.
Protein: Y117_OSHVF
Sequence: MEAVMSPMMTCVHKIMCRVDQYGNIDSYDAALNVMRKRNIQITPKESVQFKSFLRMLNMADLCFEVKEEEPCCICFRKDVIYKEVPCGHYICVECYKEPIRNVCPECNAPWPERANDPTVKQYTEEQYAHTLGGYYVTRADGTNYRSQEEYLADLDNIYREVEEADQRDNDPIESDIEEEMNESEAEEEEPVPEIAQFEALNTPPPPPTNRRPKIRRPMERARNTTRYDSEELTNMLMTEVATRVSLRGGVGDLNWITQIKNDIRKIQAASYRSRNDNMMIKYFAYLVAIIMPNECEAQRREILKLHAFRCHKRNARDCCGTCGMDMCNQRTYSIREIPNNNGSRLITVCGRCNQINNVNNTAFRLLYNYM
What are the official names of this protein?
Putative RING finger protein ORF117.