PharMolix/UniProtQA huggingface dataset:
Protein: RL32_PSEA7
Sequence: MAVQQNKKSRSARDMRRSHDALESNALSVEKSTGEVHLRHHVSPDGFYRGRKVVDKGSDE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: KDM5B_HUMAN
Sequence: MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEARLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFHTSCVAVPSISQGLRIWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLKFVQDRVGSGLLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWDNRTSYLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERWERVKKMRTPKKKKIKLSHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCLQPEGDEVDWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAPSRK
What is the function of this protein?
Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code (PubMed:24952722, PubMed:27214403, PubMed:28262558).  Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'.  Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'.  Acts as a transcriptional corepressor for FOXG1B and PAX9.  Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5 (PubMed:24952722).  In contrast, may act as a tumor suppressor for melanoma.  Represses the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 5B, Cancer/testis antigen 31, CT31, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1, Retinoblastoma-binding protein 2 homolog 1, RBP2-H1, [histone H3]-trimethyl-L-lysine(4) demethylase 5B.
What is the protein family that this protein belongs to?
Belongs to the JARID1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYH_XANOR
Sequence: MIKPRTPPGIMELLPREQIAFQRMLDVIRRNYERFGFLPIETPVFELSDVLLTKSGGETERQVYFVQSTGALANAAAAADEGAENGGLPELALRFDLTVPLARYVAEHEHDLSFPFRRYQMQRVYRGERAQRGRFREFYQCDIDVIGKDALSIRYDAEVLAVIHAVFAELGIGDFKVQLNNRKLLRGFFESLGVAEGELQLAVLREVDKIDKRGADYVRDTLVGEGFGIAAEQVARILAFVAVRSEGHADALAQLQALEASVGASATLGEGIAELREVLELVKALGVPERAYCLNFSIARGLDYYTGTVYETTLTDHPQIGSICSGGRYESLASHYTKSRLPGVGISIGLTRLFWQLREAGLIQGIAESSVQAMVALMDETRLDDVLDIARRLRIAGINTEVQMEPKKVGKQFQYAARAGIRFVVLAGDDELARGVVAVKDLVREQQFDVARDELASTLLVELEQAKAMP
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACBG2_MOUSE
Sequence: MTQEKKAEDLERGTDATSAVPRLWSTHCDGEVLLRLSKHGPGHETPMTIPELFQESAERFSAYPALASKNGKKWDTLTFSQYYEMCRKAAKSLIKLGLQRFQCVGILGFNSVEWVVTALGTILAGGLCVGIYATNSAEACQYVIQQANVSILIVENDQQLQKILLIPPDKMETVKAIVQYKLPLMESMANLYSWNDFMELGNDIPNIQLDRVILSQKANQCAVILYTSGTTGTPKGVLLSHDNITWTAGAMSQEMEINRVSGKQNTIVSYLPLSHIAAQLTDIWIPIKIGALTFFAQPDALRGTLVYTLQEVKPTLFMGVPRIWEKMQDTIKENVARSSRLRKKAFAWAKMLGLKVNTKRMLGKRDIPMNYRMAKALVFAKVRTSLGLDNCHAFFSSASPLSQDVSEFFLSLDIPIGEIYGMSECSGPHTVSNKSVYRVLSCGKVLSGCKNMLYNQNKEGVGEVCMWGRHVFMGYLNKEEATLEALDENGWLHSGDIGRLDSHDFLYITGRIKEILITAGGENVSPIPIETLVKEKIPIISHAMLVGDKAKFLCMLLTLKCETDRKSGEPLNKLSVEAKSFCQMLGSQATTVSDILKSRDQVVYTAIQYGIDIVNQQAMSDSHRIRKWIILEKDFSIQGGELGPTSKLKRSVITQKYKAQIDSMYLS
What is the function of this protein?
Catalyzes the conversion of fatty acids such as long chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.  Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.  Has increased ability to activate oleic and linoleic acid.  May play a role in spermatogenesis.
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase ACSBG2, Acyl-CoA synthetase bubblegum family member 2, Arachidonate--CoA ligase ACSBG2, Bubblegum-related protein.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: MURC_BIFAA
Sequence: MSDNQREAGTIILDPTHASFAPEETVHDLGATHFIGIGGAGMSVLAEMLHEQGVEVDGSDREPSAKTDRLQSLGITVEFGQQAKNVEGKNTVVFSSAIKPDNPEIVAAHEAGERIVHRSDILALLMNAKRAVTVAGAHGKTTTSSMLAHILVNAGEGELADPSYAIGGSIQGKDGAILDGGHAGKGNVLVAEADESDGSFAKYHPQIAIITNSEADHLDHYGTQDNYRAAFVDHAGHATKAVIMCGDDEGNLAVLRALDATVAGRTIVYSTRNAAELGDLNGATLVRIESESETAESGAEHFTLHIPGGLIGEEERRIAVTLTVPGIHNARNASAAIIAAALLGMDVERASAAVTSFLGAARRFQVRGTVSQVTVVDDYAHHPTEIAALLDAARRRYPQSKIRVIFQPHLFSRTRFFSSEFAQALAKADDVIVTGIFPAREKQEDFPDVTPATIVDEALKLEHEPAKDWIRGVEDMHTAAQMMVMRAHHGDVIFTVGAGDITQMDEVILHALEAHRWDCEG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_VIBA3
Sequence: MSLLAVGINHNTASVELREKVAFGPDKLSEALKQLNANAHVNGSVILSTCNRTEVYCDVKGVAKNKLIDWLSVFHQVSPEELKPSIYIHEEQAAIKHLMRVACGLDSLVLGEPQILGQVKQAYTDSRDNKSVDASMEKLFQKSFSVAKRVRTETEIGGSAVSVAYAACTLAKHIFESIAESTVLLVGAGETIELVAKHLSANGCTKMIVANRTRERALGLAEEFGAEVISLNEIPDHLHRADIVISSTASPLPIIGKGMVETALKTRKHQPMLLVDIAVPRDVESQVGDLNDAYLYSVDDLQSIVDGNIEQRKVEAIQAEAIVSEESAAFMSWMRSLQAVDSIRDYRKSANEIREELLSKSLQSLAAGGDPEKVLLELSNKLTNKLIHAPTRALQSAAEQGEPAKLTVIRQSLGLENPQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: IF1_VIBVU
Sequence: MAKEDVIEMQGTVLDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVEMTPYDLSKGRIVFRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_LISW6
Sequence: MESLLQKVYDQENLTKAEMNILATEIFEGRLSKTKMAAFLMALKVKGETAEEMAGIAEAMQEVAIQVAFPAGTAMDNCGTGGDKSNSFNISTTSAFVLAAAGIPVAKHGNRSISSRSGSADVCQELGIDINMRPEDMTYLLEKVGIAFLFAPHVHPNMKYVMDVRKELGTPTIFNLIGPLTNPVHLETQLMGIYRRDLLKQTAEVLGQLGRKRAVVLNGAGFMDEASLAGENHYALYESGEVQLFTLSPEEVGLANYPLEAIRGGDAKENAAILRSVLEGEPGAHLDTVLLNAGFGLFASGKVATVKEGVNLARDLVRSGLAKQKLADLITYQKEVLTK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: YIIR_ECOLI
Sequence: MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDIQTAAFCLVCLLWPTAAVTVKRLHDRGRSGAWAFLMIVAWMLLAGNWAILPGVWQWAVGRFVPTLILVMMLIDLGAFVGTQGENKYGKDTQDVKYKADNKSSN
What are the official names of this protein?
Uncharacterized protein YiiR.
Protein: G3PA1_ARATH
Sequence: MASVTFSVPKGFTEFSGLRSSSASLPFGKKLSSDEFVSIVSFQTSAMGSSGGYRKGVTEAKLKVAINGFGRIGRNFLRCWHGRKDSPLDIIAINDTGGVKQASHLLKYDSTLGIFDADVKPSGETAISVDGKIIQVVSNRNPSLLPWKELGIDIVIEGTGVFVDREGAGKHIEAGAKKVIITAPGKGDIPTYVVGVNADAYSHDEPIISNASCTTNCLAPFVKVLDQKFGIIKGTMTTTHSYTGDQRLLDASHRDLRRARAAALNIVPTSTGAAKAVALVLPNLKGKLNGIALRVPTPNVSVVDLVVQVSKKTFAEEVNAAFRDSAEKELKGILDVCDEPLVSVDFRCSDFSTTIDSSLTMVMGDDMVKVIAWYDNEWGYSQRVVDLADIVANNWK
What is the function of this protein?
Involved in the photosynthetic reductive pentose phosphate pathway (Calvin-Benson cycle).  Catalyzes the reduction of 1,3-diphosphoglycerate by NADPH (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic, NADP-dependent glyceraldehydephosphate dehydrogenase A subunit 1.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Peripheral membrane protein. Plastid, chloroplast stroma.
Protein: HEM1_ACET2
Sequence: MNVIMAGIDYTLAPIDIREKFSFTKSTLQAVYNDLLKNENIFGAVIVSTCNRTELYLSCEEGLYINPFELLCDAANFDYEEYSNMHVLRTGVDVIRHLCELACGVKSQIWGEDQIITQVRNAIELAREMNASDSTLEVMFRIAVTSAKKVKTTLKLSSTERSIAYSALKIIKSKENISKALVIGNGEIGRLMASILIENGYDTTITLRRYRHGDNIIPLGAKTIEYVARYEKLKDCDVVISATLSPHYTLEIDKIDRIKYPRLFIDLAVPRDIDPKIKSLDNVELYDLDSIYAGEVDKNRTEQMIQVKKIIDKYIFDYYRWYEYRKRLVLT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HSLU_SALSV
Sequence: MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQAEQQQEPSAARQTFRKKLREGQLDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKPRKLKIKDAMKLLVEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGETSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASVTVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNETTENIGARRLHTVLERLMEEISYNASDLHGQNITIDAEYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_ANTLI
Sequence: MEELQGYLEKDKSWQQHLLYPLLFQEYIYALAHDHSLSGSIFYEPVEVFGYDKKSSLALVKRLNTRIYQQNFLISSVNGSNQKRLVGXNNFFXSLFXSQMIIESFAIFXEILFLRALVSFFGEKKVLKYPNLPSIHSIFPFLEXKLPHLNYVSDILIPHPIHMXILVQILQCWIQDVPFLHSLRFFLHEYHNWNSLLITHKKSICLFSKENKRLFRFLYNSYVSEFEFLLVFFRKQSSYLRLRSSGTFLERTHFYGKIEHFQIXHFAFYSSMSXLFPVVXLKXPFMHYVRYQGKALLASKGTHLVMKKWKYHFVTLWQYYFHFWSQLYRIRINXLSNYSFYFLGYLSSVLINFSAVRNQMLENSFLIDIITKKFDSIIPVILLIESLSKAQFCTVSGHPISKPIWADLSDSDILDRFGWICRNLSHYHSGSSKKQDLYRIKYILRLSCARTLARKHKSTVRTFLRRLGPGLLEEFFTEEERVLSLIFPKTISFILHGSHKERIWYLDIIRMNDLVNYSXLX
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYMPK_MOUSE
Sequence: MASSSGDSVTRRSVASQFFTQEEGPSIDGMTTSERVVDLLNQAALITNDSKITVLKQVQELIINKDPTLLDNFLDEIIAFQADKSIEVRKFVIGFIEEACKRDIELLLKLIANLNMLLRDENVNVVKKAILTMTQLYKVALQWMVKSRVISDLQEACWDMVSSMAGEIILLLDSDNDGIRTHAIKFVEGLIVTLSPRMADSEVPRRQEHDISLDRIPRDHPYIQYNVLWEEGKAAVEQLLKFMVHPAISSINLTTALGSLANIARQRPMFMSEVIQAYETLHANLPPTLAKSQVSSVRKNLKLHLLSVLKHPASLEFQAQITTLLVDLGTPQAEIARNMPSSKDSRKRPRDDTDSTLKKMKLEPNLGEDDEDKDLEPGPSGTSKASAQISGQSDTDITAEFLQPLLTPDNVANLVLISMVYLPETMPASFQAIYTPVESAGTEAQIKHLARLMATQMTAAGLGPGVEQTKQCKEEPKEEKVVKPESVLIKRRLSVQGQAISVVGSQSTMSPLEEEVPQAKRRPEPIIPVTQPRLAGAGGRKKIFRLSDVLKPLTDAQVEAMKLGAVKRILRAEKAVACSGAAQVRIKILASLVTQFDSGFKAEVLSFILEDVRARLDLAFAWLYQEYNAYLAAGTSGTLDKYEDCLICLLSGLQEKPDQKDGIFTKVVLEAPLITESALEVIRKYCEDESRAYLGMSTLGDLIFKRPSRQFQYLHVLLDLSSHEKDRVRSQALLFIKRMYEKEQLREYVEKFALNYLQLLVHPNPPSVLFGADKDTEVAAPWTEETVKQCLYLYLALLPQNHKLIHELAAVYTEAIADIKRTVLRVIEQPIRGMGMNSPELLLLVENCPKGAETLVTRCLHSLTDKVPPSPELVKRVRDLYHKRLPDVRFLIPVLNGLEKKEVIQALPKLIKLNPIVVKEVFNRLLGTQHGEGNSALSPLNPGELLIALHNIDSVKCDMKSIIKATNLCFAERNVYTSEVLAVVMQQLMEQSPLPMLLMRTVIQSLTMYPRLGGFVMNILARLIMKQVWKYPKVWEGFIKCCQRTKPQSFQVILQLPPQQLGAVFDKCPELREPLLAHVRSFTPHQQAHIPNSIMTILEATGKQEPEVKEAPSGPLEEDDLEPLALALAPAPAPAPAPAPAPAPAPRPPQDLIGLRLAQEKALKRQLEEEQKQKPTGIGAPAACVSSTPSVPAAARAGPTPAEEVMEYREEGPECETPAIFISMDDDSGLAETTLLDSSLEGPLPKEAAAVGSSSKDERSPQNLSHAVEEALKTSSPETREPESKGNS
What is the function of this protein?
Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing.  Specific component of the tight junction (TJ) plaque, but might not be an exclusively junctional component.  May have a house-keeping rule.  Is involved in pre-mRNA polyadenylation.  Enhances SSU72 phosphatase activity (By similarity).
What are the official names of this protein?
Symplekin.
What is the protein family that this protein belongs to?
Belongs to the Symplekin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Nucleus, nucleoplasm. Note=Cytoplasmic face of adhesion plaques (major) and nucleoplasm (minor) (in cells with TJ). Nucleoplasm (in cells without TJ). Nuclear bodies of heat-stressed cells. Colocalizes with HSF1 in nuclear stress bodies upon heat shock.
Protein: HBA2_TORMA
Sequence: VLSEGNKKIIKNLLQKIHSQTEVLGAEALARLFECHPQTKSYFPKFSGFSANDKRVKHHGDLVLKALVDTNDHLDDLPHHLHKLAEKHGKDLLVDPHNFKLFSDCIAVTLAAHLQEKSPETHCAVDKFLEEVTYQLSSLYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-2, Alpha-2-globin, Hemoglobin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RTC6_YEAST
Sequence: MFLQTLRLTMPRMFLHMKPSPITITRACTVPSLLSVAAPQPALVAANRPLVFNRGFKVRTSVKKFCSDCYLVRRKGRVYIYCKSNKKHKQRQG
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:25609543, PubMed:24675956).  bL36m may be involved in a process influencing telomere capping (PubMed:18845848, PubMed:20691087).
What are the official names of this protein?
54S ribosomal protein RTC6, mitochondrial, Mitochondrial large ribosomal subunit protein bL36m, Restriction of telomere capping protein 6, Translation associated element 4.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: RUVB_MICAN
Sequence: MAIKRSHNSPPATEENLLTPNPTIEETEKAAAEIRPQSLEDYIGQQDLKANLKVTIAAAKARQEAIDHLLFYGPPGLGKTTMALILAAEMGVNCRITAAPALERPRDITGILINLQPRDILFIDEIHRLNRVTEELLYPAMEDYRLDVTIGKGQAAKIRSISLPPFTLIGATTKVGSLTSPLRDRFGLIQRLRFYAVEELTAIILRSATIFNIPITEAGAIEIARRSRGTPRIANRLLKRVRDYVQVKGETIISPQLAAEGLNQLNVDSMGLDWTDRLVLKTMIQQFQGKPVGLEAVAAATGEDAKTIEEVYEPYLLQIGYLNRTPRGRVVTSAAYEHLGLLAKLPKNKDRSLPLFEF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: LPLA_SHIB3
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITKAFFAHYGERVEAEIISPDKTPDLPNFAEIFARQSSWEWNFGQAPAFSHLLDERFSWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPDQEKELRELSTWIAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_NOVAD
Sequence: MKIAVLPGDGIGPEVTREAVRVIEALGLGDIEMKEAPVGGAAYKAYGHPLPPETLEIARLSDGILFGAVGDPDCDSLERHLRPEQAILGLRKALTLFANLRPARVFKGMEDFSALRPEVAGAIDLLIVRELNGDVYFGEKGFRTAANGDREGYDVMSYSESEVRRIAHVAFRAAMGRKKRLCSVDKANVLETSQLWRDVMLEVAKDYPEVALEHMYVDNAAMQLVRAPGNFDVVVTGNLFGDILSDQASMCVGSIGLLASASLGERETEYGTFGLYEPIHGSAPDIAGKGLANPMATILSAAMLLRHSLGLEVAADRIEAAVAKALADGVLGRDLGGTAGTTEIGDAVLARL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDCD5_MOUSE
Sequence: MADEELEALRKQRLAELQAKHGDPGDAAQQEAKQREAEMRNSILAQVLDQSARARLSNLALVKPEKTKAVENYLIQMARYGQLSGKVSEQGLIEILEKVSQQTEKKTTVKFNRRKVMDSDEDDADY
What is the function of this protein?
May function in the process of apoptosis.
What are the official names of this protein?
Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, Protein TFAR19.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: KT33B_MOUSE
Sequence: MPYNCCLPAMSCRTSCSSRPCVPPSCHGCTLPGACNIPANVGNCNWFCEGSFNGNERETMQFLNDRLASYMEKVRQLERENAELECKIQERNQQQDPLVCPAYQAYFRTIEELQQKILCGKSENGRLVVQIDNAKLAADDFRTKYESELSLRQLVESDLNGLRRILDELTLCKSDLEAQVESLRQELLCLKQNHEEEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRCQYEALVETNRREVEEWFTTQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRNSLENTLAESEARYSSQLSQVQCLITNVESQLGEIRADLERQNQEYQVLLDVKARLECEINTYRGLLESEDCKLPCNPCATTNACDKPIGPCVTNPCVTRSRCGPCNSFGC
What are the official names of this protein?
Keratin, type I cuticular Ha3-II, Hair keratin, type I Ha3, Keratin, type I cuticular Ha3, Keratin-33B, K33B.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: CT51B_CONAE
Sequence: MLCLPVFIILLLLASPAASNPLKTRIQSDLIRAALEDADMKNEKNILSSIMGSLGTIGNVVGNVCCSITKSCCASEE
What are the official names of this protein?
Conotoxin Ar5.1 b, Conotoxin ArMLCL-021.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_CELJU
Sequence: MARVKRGVEARRRHKKVLKAAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRVKKRNFRALWITRINAQSRAEGLTYSQLIAGLKKASIVLDRRVLADLAVYDKAAFAAVVAKAKSALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ATPE_SHEPC
Sequence: MAAMTVHLDIVSAENSIFKGRVACLQVTGVEGELGILPGHAPLLTTIKPGMARIIKQDGSEEVIYLSGGFLEVQPNSIAVLADVVMRADEIDEQAALEAKRRAEAHMADAGADFDYDAAMVELAKAMAQLRVVETIKKNIAR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IF1C_OSTTA
Sequence: MASNRELIEMEGVVVESLPNAMFQVELENGFQVLAHISGKIRRNSIKILLGDRVTVELTPYDLTKGRIIYRLRKDRTQ
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.