PharMolix/UniProtQA huggingface dataset:
Protein: ACCD_ACTP2
Sequence: MSWIERILGRTSSSSSSSKSKVPEGVWTKCTSCEQVLYSEELKRNMHVCPKCNHHMRFDARTRLLSLLDQDSAQEIAAELEPQDVLKFKDLKKYKDRLTAAQKQTGEKDSFITMYGTLHNMPVVVASFNFEFMGGSMGSVVGAKFVRAAERALADNIPFICFSASGGARMQEALFSLMQMAKTSAILAKMREKGIPFISILTDPTLGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVREKLPEGFQRAEFLLEHGAIDMIVQRKDMRDTLARLCAKMTNKPTPFKTAELIVEEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_PECAS
Sequence: MKLQLVAVGTKMPDWVQTGFTDYLRRFPKDMPFELLEIPAGKRGKNADIKRILEREGEQMLAAVGKGNRIVTLDIPGTRWETPHLAQQLERWKQDGRDVSLLIGGPEGLSPECKAAAEQSWSLSPLTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDB7_HUMAN
Sequence: MEARVERAVQKRQVLFLCVFLGMSWAGAEPLRYFVAEETERGTFLTNLAKDLGLGVGELRARGTRIVSDQNMQILLLSSLTGDLLLNEKLDREELCGPREPCVLPFQLLLEKPFQIFRAELWVRDINDHAPVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTISPNAYFHINVHDSGEGNIYPELVLNQVLDREEIPEFSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVSVSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGGLSGKCTVVVDVTDINDNRPELLLSSLTSPIAENSPETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVENFYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLRLPEAAPDQANSLTVYLVVALASVSSLFLLSVLLFVAVRLCRRSRAAPVGRCSVPEGPFPRHLVDLSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNLLPQSTGREVEENRPFQNNLGF
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-7, PCDH-beta-7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: JANA_DROTE
Sequence: MNRLQLFSKGLRLIHKMSEEALAGVPLVHISPEGIFKYVLINVIDGGDASKAVVRGFDDCTWHADIFDREEEVFKKLGLRAECPGGGRIEHNPEKKYLKVYGYSQGFGKADHAQTKRILATKYPDYTIETSDEGY
What is the function of this protein?
JanA and janB regulate somatic sex differentiation.
What are the official names of this protein?
Sex-regulated protein janus-A.
What is the protein family that this protein belongs to?
Belongs to the janus family.
Protein: FOLD_STRPF
Sequence: MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDPASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPNHINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKHAVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQYIKEGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQSALRSTHK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: COAX_LISMO
Sequence: MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGIIISSVVPPIMHAMETMCVRYFNIRPLIVGPGIKTGLNLKVDNPREIGSDRIVNAVAASEEYGTPVIVVDFGTATTFCYIDESGVYQGGAIAPGIMISTEALYNRAAKLPRVDIAESSQIIGKSTVSSMQAGIFYGFVGQCEGIIAEMKKQSNASPVVVATGGLARMITEKSSAVDILDPFLTLKGLELLYRRNKPTTEK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SQS1_CANGA
Sequence: MAKRHKHFESRGGFRKKRGGGRGSQRGRGSKRGRGGRFRGFEETERSASEPGAWLNSSVPLGDGDLSNPDMMVDNYRPRKHISQDTITDHYFGRKSSLKLNSMRMAGLRHNDWRDPNNGNSASFRKRPIEFIKANCTYDPSRDLILQLANRSKNQESKEPEEDANKCSEYAEHSEKDMEIDTAATENDANISYDESDTDQEIGNFNHSIENSKHNNNISECDITAVTDQELFFVDEEGMDISQKPTKVVHITEHEKKMGSNVEFHNVLTVGKVEISLNQDENDEVYVDRKPTAKYHPFHNYISNVIERMQEEENIDSDDFEDEDDIYLDNSGNDMPETELDQDEIIDLQRHDDKDHAVQTCAIPTNTLSNDLDTLHITESNDDRITINNHNMDSTVETDKEKDPEFGFLEEDYAVNTSEVIVDNIRLGLNDNSYFLKCYRFFGDYSFHWIDQEAFVSFLTEDLELPMNRVGAYLAYVKNSLVPDETPPSPTYSDIPFSDTSNESDEDNALPNVDAVSSCSNDDEDEELGDDVDDLVSYSLKYANSRNIDYETRALEFTGKGKKKKLLVNEQLDLDNETMETLQAKLSKRMENKAKKRRLKEDFIDKENMNSDDLFLKYPYGFHVQNIRDEFELFLTRNKDRMSFPPLDPHGNKVITKFATCYNIKSSKVGKGNHTHIMVEKVKKTKWSRPNYNMVLQLTRQRPVFMRIDVRRPKEDAIKENSGRRGPTAKFHVKEGEVVGENAPEIGQDNIGRRMLEKLGWSSGEGLGAHGNKGISIPVMARVKKSKSGLRHSKEDEDTGRSSSFRKK
What is the function of this protein?
May be involved in splicing.
What are the official names of this protein?
Protein SQS1.
What is the protein family that this protein belongs to?
Belongs to the SQS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NIR_LEPMC
Sequence: MAATLPLLTQGIEPVSGESYSPPGERHVQATWGSKDGNISNTEWNDPEANRLPEKVAELEKKGELNNSHPRRRVVVVGLGMVGVAFIEKLMKYDIKRREYDIIVIGEEPHLAYNRVGLTSFFQHRQVENLYLNPQEWYSSMPEDSLHYHLNTLVTEIDSENKTVKTSSGQAVSYDILVLATGSSS
What are the official names of this protein?
Nitrite reductase [NAD(P)H].
Protein: RL16_SALTY
Sequence: MLQPKRTKFRKMHKGRNRGLAAGADVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: FGD_TSUPD
Sequence: MAKLQLGYKASAEQFGPRELVEIAVAAEAAGMDSVAVSDHFQPWRVNGGHAPFSLAWMAAVGERTERVKIGTSVMTPTFRYNPAVIAQAFASMACMYPDRIFLGVGSGEALNEYATGFQGEWPEFKERFARLRESVRLMRELWSGEISNFDGDYYHTKDAVLFDIPERPVPVYIAAGGPVVAKYAGRAGDGMICTSGKGMDLYTEKLIPAAKEGAELGGRDFDALDKMIEIKISYDPDPELALENTRFWAPLSLTAEQKHSVNSSAEMERLADELPIEQVAKRWIVASDPDEAVAAVKQYTDAGLNHLVFHAPGHDQRRFLDNFQRDLEPRLRALG
What is the function of this protein?
Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
What are the official names of this protein?
F420-dependent glucose-6-phosphate dehydrogenase, FGD, G6PD.
What is the protein family that this protein belongs to?
Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
Protein: QOX2_STAS1
Sequence: MSKFKSLLLLFGSLILLSGCSNVEVLNPKGPMASDSKFLIMYSIIFMLVIIAAVLILFTVFLYKYRIGNTDESGKMHHNSLLETIWFIIPVIIVIALAIPTVNSLYNYEEKPQKEDDPLVVYATSAGYKWFFSYPEEKIETVNHLTIPKDRPVVFKLQSMDMMTSFWIPQLGGQKYAMTGMTMDWTLTASEEGTFRGRNSNFNGEGFSRQTFDVNSVSQSKFEDWVKDAKKQKVLDQDTFDKQLLPTTENKNLTFSGTHLAFVDPAADPEYIFYAYDRYNFVQKDPNFNTEEERTADVLDKPDQPARKPEITNANYERHGMKAMILGNNEPYDSEFKDEESHNMDEMEKISEGAKDEKASKIEKKDHENGGGH
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.  Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I (By similarity).
What are the official names of this protein?
Probable quinol oxidase subunit 2, Quinol oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LRIF1_HUMAN
Sequence: MSNNLRRVFLKPAEENSGNASRCVSGCMYQVVQTIGSDGKNLLQLLPIPKSSGNLIPLVQSSVMSDALKGNTGKPVQVTFQTQISSSSTSASVQLPIFQPASSSNYFLTRTVDTSEKGRVTSVGTGNFSSSVSKVQSHGVKIDGLTMQTFAVPPSTQKDSSFIVVNTQSLPVTVKSPVLPSGHHLQIPAHAEVKSVPASSLPPSVQQKILATATTSTSGMVEASQMPTVIYVSPVNTVKNVVTKNFQNIYPKPVTEIAKPVILNTTQIPKNVATETQLKGGQHSQAAPVKWIFQDNLQPFTPSLVPVKSSNNVASKILKTFVDRKNLGDNTINMPPLSTIDPSGTRSKNMPIKDNALVMFNGKVYLLAKKGTDVLPSQIDQQNSVSPDTPVRKDTLQTVSSSPVTEISREVVNIVLAKSKSSQMETKSLSNTQLASMANLRAEKNKVEKPSPSTTNPHMNQSSNYLKQSKTLFTNPIFPVGFSTGHNAPRKVTAVIYARKGSVLQSIEKISSSVDATTVTSQQCVFRDQEPKIHNEMASTSDKGAQGRNDKKDSQGRSNKALHLKSDAEFKKIFGLTKDLRVCLTRIPDHLTSGEGFDSFSSLVKSGTYKETEFMVKEGERKQQNFDKKRKAKTNKKMDHIKKRKTENAYNAIINGEANVTGSQLLSSILPTSDVSQHNILTSHSKTRQEKRTEMEYYTHEKQEKGTLNSNAAYEQSHFFNKNYTEDIFPVTPPELEETIRDEKIRRLKQVLREKEAALEEMRKKMHQK
What is the function of this protein?
Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin (PubMed:23542155).  Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases (PubMed:17455211).  Also required for silencing of the DUX4 locus in somatic cells (PubMed:32467133).
What are the official names of this protein?
Ligand-dependent nuclear receptor-interacting factor 1, HP1-binding protein enriched in inactive X chromosome protein 1, HBiX1, Receptor-interacting factor 1.
What is the protein family that this protein belongs to?
Belongs to the LRIF1 family.
What are the subcellular locations of this protein?
Chromosome. Nucleus matrix. Note=Localizes to Barr body; recruited by SMCHD1.
Protein: EFP_STRP6
Sequence: MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQELLYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVVNVPDFIEAGQKLIINTAEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_SHIFL
Sequence: MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: VKT4_PSEAU
Sequence: MSSGGLLLLLGLLTLWEGLTPVSSKDHPRFCELPADPGPCNGLFQAFYYNPVQRTCLKFRYGGCKGNPNTFKTIEECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor mulgin-4.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_PSEAE
Sequence: MALSVEEKAQIVNEYKQAEGDTGSPEVQVALLSANINKLQDHFKANGKDHHSRRGLIRMVNQRRKLLDYLKGKDVSRYTALIGRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ACNA_RICTY
Sequence: MPTVHNSEYIKELLVDNTSYKIYDINKAASDIGISLNKLPYSLRVLLENVLRTSGNKENLLVFKEWLKTKKSNTEIDFMPARVLMQDFTGVPAIVDLAAMRDAMQKIGCNPLKINPLIPVDLVIDHSVSVDSYGLKESFEQNVQMEMKRNIERYQFLKWGQQAFNNFKVVPPGTGICHQVNLEYLSKVVWYNDGTAYPDSLVGTDSHTTMVNGLSVLGWGVGGIEAEAAMLGQPLTMIIPEVIGVKLTGKLEGMATATDLVLTITEMLRRTKVVGKFVEFFGYGLSNLTISDRATISNMSPEYGATCGFFPIDQETIKYLEITGRETRQIKLVEKYATEQNLWYNFEDTQEYTEVLELDLSTVYSSLAGPKRPQDRVNLSFVESNFKNELPYFALENQDIDKKYAVANQNYEIGNGDVVIAAITSCTNTSNPSVMIGAALLAKKALEHGLNVKPWVKTSLAPGSKVVTEYLKISGLDKYLDALGFNLVGYGCTTCIGNSGSLNPEIENTINKNRLVVASVLSGNRNFEGRINPLTKASYLASPILVVAYALSGTLNIDLTTTPIGANIYLKDIWPSQKEIDAVIANSINPSMFIEKYADVFNGTKEWHDLHITTGTNYNWDKNSTYINNPPYFDNICSENTIKDIKSAKILAIFGDSITTDHISPAGSISKNSPAAKYLIEHNIEPLNFNSYGSRRGNHEVMMRGTFANIRIKNEMCNGVEGGFTINQLSGVQQTIYDAAMDYQAHDIPLVVFAGKEYGSGSSRDWAAKGPGLLGIKAIIAESFERIHRSNLVGMGILPLTFTGNNTRLSLKLDGSETIDIIGLSKNIRPFNLVKCVIKKQTNEISTIDLILQIFTENEINYIKHGSIMQFVVESLKG
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The apo form of AcnA functions as a RNA-binding regulatory protein.
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, Iron-responsive protein-like, IRP-like, Probable 2-methyl-cis-aconitate hydratase, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: SPC25_YEAST
Sequence: MASIDAFSDLERRMDGFQKDVAQVLARQQNHARQQLQQFQAEMRQLHNQHQHLIDELQRLATQRTALQQQIHAAQQATNTTREQWRSYHERESELSRRQSTLAAQSRELDSLLQQRGKECVQLRARWAAQSGNDAAEVALYERLLQLRVLPGASDVHDVRFVFGDDSRCWIEVAMHGDHVIGNSHPALDPKSRATLEHVLTVQGDLAAFLVVARDMLLASL
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Kinetochore protein SPC25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
Protein: UFD1_SCHPO
Sequence: MFGGSFFSSDDDGFSMMSQLRSAFHNNVNQRFDTRYRCYPVAMIPGEERPNVNYGGKVILPPSALEKLSRLNVSYPMLFDFENEAAEKKTHGGVLEFIAEEGRVYLPYWMMTTLSLEPGDLVRVINTDIAQGSYVKLQPQSVNFLDITDHRAVLENALRNFSTLTKSDIFEILYNDQVYQIKVIDVQPDDSRHVVSVVETDLVVDFDPPIGYEESLQKNKQQNIAGVQGTMVTKIGYDELVRQGDSNLMKGTGTKLNGKEVAEVPKINLLDVEKQECPAPLILPLGTYFFGYPYKAPSIEEDSKKDPNLFKFEGAGTSLRASRKTNGTMGKGSSDDPIDIDA
What is the function of this protein?
Functions at a post-ubiquitation step in the ubiquitin fusion degradation (UFD) pathway.  It is required for vegetative growth (By similarity).
What are the official names of this protein?
Ubiquitin fusion degradation protein 1, UB fusion protein 1.
What is the protein family that this protein belongs to?
Belongs to the UFD1 family.
Protein: ASI1C_DANRE
Sequence: MTAMKGDSEDSIESMRPSNLQVFANNSTLHGMSHIFAYGHMTFRRFLWTLSFMGSLGLLMYVCMDRVYYYFEFPHVTKLDEVAAPNLTFPAVTFCNLNEFRFSKITKNDLYHVGELLALLNENYQIANPHLADPEVLTLLKEKASFNGFKPKQFNMTDFYNRTGHDINEMLLQCSFRGEECFPLNFTTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAPMDSEYFSTYSITACRIDCETRYLLENCNCRMVHMPGTSTVCTPEQYKDCADPALDFLVEKDNDYCVCDTPCNMTRYGKELSMVKIPSKASAKYLAKKFNKTEQYITDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVLKDKILGSVLRKRRPHRSASDNLVIVSLHDFKISSVFLLASYMCFVCYIVLLNAACVYLPFVVGSNSGK
What is the function of this protein?
Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized.  Generates a biphasic current with a fast inactivating and a slow sustained phase.  Has high selectivity for sodium ions and can also transport lithium ions with high efficiency.  Can also transport potassium ions, but with lower efficiency.  It is nearly impermeable to the larger rubidium and cesium ions.
What are the official names of this protein?
Acid-sensing ion channel 1C, ASIC1-C, Acid-sensing ion channel 1.3-C, Amiloride-sensitive cation channel 2-C, neuronal-C, ZASIC1.3.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCA_ECO7I
Sequence: MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQIGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLALMREMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPAKWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAVASWKEQRCPKPE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RHLB_PASMU
Sequence: MQNNYLSQLRFSDLPLHHQVLAALQEKGFDYCTPIQALSLPMSLAGKDVAGQAQTGTGKTMAFLTATFHHLLTQQGDKGGRQPRALILAPTRELAVQINNDAALLTKATGLKTGLAYGGDGYEKQLKAIEQGVDILIGTTGRVIDYVKQGIVRLDKIQVVVLDEADRMFDLGFIKDIRYLLRKCPAPQHRLTMLFSATLSYKVRELAFEDMNDPEYVEIEPLQKTGHRIKEELFYPSNQDKMALLLTLLEEEWPERCIIFANTKHRCEDIWGYLAADGHRVGLLTGDVAQKKRLSLLKQFTEGHLDILVATDVAARGLHISDVSHVFNYDLPDDREDYVHRIGRTGRAGESGVSISFACEEYAMNLPAIEEYISHSIPVSQYDVAALLTLPKPYRIKRGNNNSKNSANSNRTFQKKRSLKRNF
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_BIFA0
Sequence: MASHIGKLPIEIPAGVEVTINGQEFAAKGAKGSDSYTIPEGVTAKVEGNEIIVTANDDLRPTRAKHGLARSIVASMVKGVHDGYSKSLDIVGTGYRAQMKGKGIEFSLGYSHTITVNPPEGITLELPNPNQVIVKGTDKQAVGQVAANIRKLRAPEPYKGKGIKYSDEVIRRKAGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: BAZ1B_XENLA
Sequence: MAPLLGRRPFPLVKPLSEAATGEGEEEVYMIEHSKEAFRSREEYESRLERYAERIWTCKSTGSSQLTHKEAWDEEQEVAELLKEEFPVWYEKQVLEMVHHNTISLDKLVDQSWMEIMTKYADGEECDFEVGPEKYLRAKIVKVHPLEKEEQASEKKSEGSCDSPSSDKENSNKVAQDIQLKEESNRLESLSSLRESDRARRSPRKLPTSLKKEEKKWVPPKFLPHKYDVKLLNEDKVISFVPVDSLYRSERPPNKEILRYFIRHNALRIGTGENAPWVVEDELVKKYTLPSKFSDFLLDPHKYMTLNPSSATKRKSLGSPDQKPAKKSKKSPLSPSSWSLANLKKTAVNSSSSEEEMQLMIGANLNKKGSIGKKSDKKKPKNGKSQVLNGQKISAKTRSPKKGLKSPKLKQMTLLDMAKSTPKVSRAQKGGSNTPRSSSKPNKYLPPAALHLISYYRDNKNREDRKSALSALISKVARMLSAEDRKRLPDDLQELVQKRYELLEHRKQWAVMTEEQREEYMRKKREALKARIKEKTRERKQKEREERLEKQKRYEDQDLTGKSLPTFKLVDTPEGLPNALFGDVAMVIEFLSGYSDLLLPDGQYPVTAVSLMEALAAEKGGFMYLNRGLVVLLQTLLQDEIAEDYGELGMKLSEIPLTLHSASELVRLCLRKSDSPAGENESIEKGDEDSEGSAVYQDDEVEDEYLEKLETSEFFELTTEEKLHILAALCHRILMTYSVQDHVDAKQQRSGELWKERLAILKGENDKKRAAKQKRKEQGTVKPKEEVQAAKIVKKQEKINTQQDNDAEDMISAVKSRRLQAMQAKKEKEEHEKLTKERIERETEEERSRKQKASAEKAFHEGIAKAKLVLRRSPLGTDRNHNRYWLFSDEVPGLYIEKGWVHDSINYRFSPESKQDSEQDAEESEDANSSIGCPDDSTQREEKHAETTVPKQGQNLWFLCDTQKELDELLDSLHPQGFRESQLKERLQNRYQDIMHSIHLARKQNLGLKTCDGQQELLNFLRSDIIEVATRLQKGGLGYLDDTTEFEAKVRTFENLKDFGECIVFLQAAVIKKFLQGFMAPKQKKRKHQSEEAAAKAEEQDEEKKMAEEAKVASAVEKWKVAIRDAQTFSRMHVLLGMLDACIKWDMSSENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPVLFNIPDGEWLCPACQPATARRSSRGRNYAEDSTQDEDEEEEEEESEEEEEEESDEEEEEQEMMGQRLRSRKAAKGKPGRPTRRGRPPKNNTHSRVSRQRYVEDTEADVEEMVRQSKPTSRRQNQEFQKCEEILAKLIKYRFSWPFREPFNADEIEDYTKVVTTPMDFQTMQSKCSCGSYQTVQEFLNDLKLVFGNTELYYEAGSSQLSCLEKTEQCARDLLGKHLPAHTYQRRHRKHQSPEPEPETANPGRGRKQKK
What is the function of this protein?
Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator.  Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph).  H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress.  Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure.  The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes.
What are the official names of this protein?
Tyrosine-protein kinase BAZ1B, Bromodomain adjacent to zinc finger domain protein 1B, Williams syndrome transcription factor homolog.
What is the protein family that this protein belongs to?
Belongs to the WAL family. BAZ1B subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates in pericentromeric heterochromatin during replication. Targeted to replication foci throughout S phase (By similarity).
Protein: Y2524_CUPNH
Sequence: MPEAQSRFRRRLLLYYGLFTLGLFGFVGMMGLLEKSNADALWLGYVFLFITIAIYACIGLICRTSDLNEYYVASRRVPALFNGMAIAADWMSAASFIGLAGILFASGYEGLAYVMGWTGGYCLVAFLLAPYLRKYGGYTIPDFLAARYGNGKPGGNLPVRAIAVLAASLCSFVYLVAQIQGVGLVVTRFIGVEFAVGIFFGLAGILVCSFLGGMRAVTWTQVAQYIMMIVAFLVTVSMIAWKHHHEALPQLSYGTLLSQLDAREQQLEREPAEQAVREYYRQQAILLQERIARLPDSFAQERDALDARLQDLRTRNAPLRDIKSLERERLEFPRDPAAAQQQWNQQRADALARSRHSLSSTEPYPAASEQERKTKRLNFVLLVFCLMVGTASLPHILTRLYTTPSVKETRNSVAWAVFFIALLYVSAPTLAALVKFEFFQHLVGTPYAELPQWVVQWRKVDPPVFGIRDVNGDGIVQWAEILLQPDMIVLAAPEIAGLPYVISGLIAAGALAAALSTADGLLLTIANALSHDVFYHMVDRQASHQRRVTTAKIVLLGVALFASYVTSLRPGNILFLVGAAFSLAASSFFPVLVLGIFWRRTTAAGAVAGMAAGLGVAVYYIIVNYPFFTRMTGIFGNRWFGVDPIASGAFGVPAGFAVAIIVSLLTPRNAPVIDRLVSYLRKG
What are the official names of this protein?
Uncharacterized symporter H16_A2524.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.