PharMolix/UniProtQA huggingface dataset:
Protein: YR354_MIMIV
Sequence: MTDISYYNNEIDKILWNILGDDYFTQDEFDDLVNSVANTIYQYDNEVSIDKLKVIIEFVILNKFKICYIYDNDSILNQVKYEKKSVGSKTIGKNSTNDDEDDDEDIAVIKLSDIEAGENWFKKSPKISSKQFQSVDKVEVATYEDLISHKHDYPKEIYKESHYIRRNTRLDVIKKIPQFEQKSKEWLKQRTESLTATAISVVFDEDPYKHPIVILLDKCGRGLPFVENKFVHHGNKYEQIGTMFYSFRNNVEVGEYGLLQHSGHKFIAASPDGICSKKANTGGLSKLVGRLLEIKFPFSREINNSGDLDGDICPHYYFLQVQTQLYVTEMDECDFLQCKIDEYDSWEDFVKDSNPIVPGLSKTTNLEKGCLIQLSDKNLIGSDDKEKCLYNSKYIYPPKLHMTNEEIEKWISSEIMNYHNNDLSENYMIDRVIYWRLSQVTCNLIKLNKEAFEEKIPLLQQFWDYVLFYRQHSDKLDKLIKFVEKVKEDNSAEIFSYINEDFLSLNKDSKYEPLYQEETEWRKKYNQIKAKKAQMYKNKSYNKYTKFSN
What are the official names of this protein?
Uncharacterized protein R354.
Protein: RL39_PICTO
Sequence: MARNKPLGLKIRLMKAVKSNRRVPGWVMVKTDRRVTQNYKRRNWRRSNLKA
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: PROB_LEPIN
Sequence: MKPERNSLSEKIRNAEKIVIKVGSARLSGLPSEVNDFLFQLVSDIRHLRDLGKKVILVSSGAIARGRLLLSELPSTISSGDSLAEKQALAAMGQNRLVNLYDSFFSKVNLSIAQILFGVLDLESKEGYKNLKNTFTQLVEWGILPVVNENDSVATEEVKFGDNDMLSALVSLIVEADLLIILTGVDGFLKEEKVVPFLEKISKEDLGLAGGPSGPGTGGMFTKLKSAGLLSEAGIPTAILNGKKMHVIREFLEKNSIGTLVAPSGNRVFSEEDVKEIIRKNRNGNGGNSL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALS3_ARATH
Sequence: MSATRGGPDQGPSQPQQRRIIRTQTAGNLGESFDSEVVPSSLVEIAPILRVANEVESSNPRVAYLCRFYAFEKAHRLDPTSSGRGVRQFKTALLQRLEREHDPTLMGRVKKSDAREMQSFYQHYYKKYIQALHNAADKADRAQLTKAYQTANVLFEVLKAVNLTQSIEVDREILEAQDKVAEKTQLYVPYNILPLDPDSANQAIMRYPEIQAAVLALRNTRGLPWPEGHKKKKDEDMLDWLQEMFGFQKDNVANQREHLILLLANVHIRQFPKPDQQPKLDDQALTEVMKKLFKNYKKWCKYLGRKSSLWLPTIQQEMQQRKLLYMALYLLIWGEAANLRFMPECLCYIYHHMAFELYGMLAGNVSPMTGENVKPAYGGEEDAFLRKVVTPIYEVIQMEAQRSKKGKSKHSQWRNYDDLNEYFWSVDCFRLGWPMRADADFFCLPVAVPNTEKDGDNSKPIVARDRWVGKVNFVEIRSFWHVFRSFDRMWSFYILCLQAMIIMAWDGGQPSSVFGADVFKKVLSVFITAAIMKLGQAVLDVILNFKAHQSMTLHVKLRYILKVFSAAAWVIILPVTYAYSWKDPPAFARTIKSWFGSAMHSPSLFIIAVVSYLSPNMLAGVMFLFPLLRRFLERSNYRIVMLMMWWSQPRLYVGRGMHESAFSLFKYTMFWVLLIATKLAFSYYIEIRPLVAPTQAIMKARVTNFQWHEFFPRAKNNIGVVIALWAPIILVYFMDSQIWYAIFSTLFGGIYGAFRRLGEIRTLGMLRSRFESLPGAFNDRLIPDGKNQQKKKGIRATLSHNFTEDKVPVNKEKEAARFAQLWNTIISSFREEDLISDREMDLLLVPYWADRDLDLIQWPPFLLASKIPIALDMAKDSNGKDRELKKRIESDTYMKCAVRECYASFKNIIKFVVQGNREKEVIEIIFAEVDKHIDTGDLIQEYKMSALPSLYDHFVKLIKYLLDNKEEDRDHVVILFQDMLEVVTRDIMMEDYNISSLVDSSHGGTWHGGMIPLEQQYQLFASSGAIRFPIEPVTEAWKEKIKRIYLLLTTKESAMDVPSNLEARRRISFFSNSLFMDMPMAPKVRNMLSFSVLTPYYTEEVLFSLRDLETPNEDGVSILFYLQKIFPDEWNNFLERVKCLSEEELKESDELEEELRLWASYRGQTLTRTVRGMMYYRKALELQAFLDMAMHEDLMEGYKAVELNSENNSRGERSLWAQCQAVADMKFTYVVSCQQYGIHKRSGDPRAQDILRLMTRYPSLRVAYIDEVEEPVKDKSKKGNQKVYYSVLVKVPKSTDHSTLAQNLDQVIYRIRLPGPAILGEGKPENQNHAIIFSRGEGLQTIDMNQDNYMEEALKMRNLLQEFLTKHDGVRHPSILGLREHIFTGSVSSLAWFMSNQETSFVTIGQRLLANPLRVRFHYGHPDVFDRLFHLTRGGVSKASKVINLSEDIFAGFNSTLREGNVTHHEYIQVGKGRDVGLNQISMFEAKIANGNGEQTLSRDIYRLGHRFDFFRMMSCYFTTVGFYFSTLITVLTVYIFLYGRLYLVLSGLEQGLSTQKGIRDNTPLQIALASQSFVQIGFLMALPMLMEIGLERGFRTALSEFVLMQLQLAPVFFTFSLGTKTHYYGRTLLHGGAKYRSTGRGFVVFHAKFADNYRLYSRSHFVKGLEMMLLLVVYQIFGSAYRGVLAYLLITISMWFMVGTWLFAPFLFNPSGFEWQKIVDDWTDWNKWINNIGGIGVPAEKSWESWWEEEQEHLRYSGKRGIVVEILLALRFFIYQYGLVYHLTITEKTKNFLVYGVSWLVIFLILFVMKTVSVGRRRFSASFQLMFRLIKGLIFMTFIAIIVILITLAHMTIQDIIVCILAFMPTGWGMLLIAQACKPVVHRAGFWGSVRTLARGYEIVMGLLLFTPVAFLAWFPFVSEFQTRMLFNQAFSRGLQISRILGGHRKDRSSRNKE
What is the function of this protein?
Involved in callose synthesis at the forming cell plate during cytokinesis.  During plant growth and development, callose is found as a transitory component of the cell plate in dividing cells, is a major component of pollen mother cell walls and pollen tubes, and is found as a structural component of plasmodesmatal canals (By similarity).
What are the official names of this protein?
Callose synthase 3, 1,3-beta-glucan synthase, Protein GLUCAN SYNTHASE-LIKE 12.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 48 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIM_BIFAA
Sequence: MSDDPSTNDALGTLRAAIKQAVTDVRGQTPLAQSFTNFVTINLVANAQLAAGGTAAMSYLPDDVIATAEIAGSNYINVGTLLPFFKNALPEIARKLHENGKTWVLDPVAAGIGETRTAILESFRDVPPTIVRGNASEIIALDAMWGLADADSTTPATRPAGVEAVDEVDAAVDAAKRLARHLAKRSPVGAGAVAVSGAVDLVTDGERTFRLPGGSAMMTKITGAGCSLGGVTATYLAVAEPLVAALAASLLYDRASEIAEVKSDGPGSFQVALLDALWNVTADQVAASDIIETN
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: UQCC4_XENTR
Sequence: MWGSLCKAPLLRLRPTFAAVSNVKTIHIKASPDYNEGIDKSKPLKFSTSKASHRHWTVAKSLGSNQQRPWWKVVPLSVFLTTVLLWAIFRKETDIDEAIYKPIEQLQDESENK
What is the function of this protein?
Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation.
What are the official names of this protein?
Ubiquinol-cytochrome-c reductase complex assembly factor 4, Protein ccsmst1.
What is the protein family that this protein belongs to?
Belongs to the UQCC4 family.
Protein: DHSD_CHOCR
Sequence: MITFQWLIVRVVALFISLTILIDIEMFVVMLSFLIIHISIGLKAIIHDYIHFQKIKLMLLILLRVSAIEISRSFRTFYIIIKNT
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase membrane anchor subunit, Succinate dehydrogenase, subunit IV.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYRC_TERTT
Sequence: MTDSLTLLRPDDWHIHLRDGTALETTVPHAAASFARAIIMPNLVPPVTNAEEALAYRARIEAQIPAETPFEPLMVLYLTNNTTPETIAAAKAAGVVACKLYPAGATTNSASGVTDIQHIYPALEEMERQGVLLLLHGEVTDSAIDIFDREAVFIERTLRKVVADFPKLKIVLEHITTQQAAEFVAQAPDNVAATITAHHLLYNRNHMLAGGIRPHYYCLPILKRQTHQQALVAAATSGSPKFFLGTDSAPHAKSRKEAACGCAGSYTAFAAIELYAEAFEDAGALDRLEGFASHFGPDFYGLPRNSDTITLRREPWSVPDTLTFGDESLVPVKAGETLNWRVQK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: SYFB_METMP
Sequence: MPTINVNKVDLERLSNISLSDKLIEDRFPMMGVEVEEIFEEVDKNGKKQNMVQFSINPDRPDYLSVEGLARGFRGFMGITTGIQEFEVLDSDIKVTVEENETRPYVAFALVKNVLMDEFVLESMINLQEKLHWAIGRDRKKLAIGIHDFDKVKAPFTYKEIKGDEIKFVPLGYEDEEMTPREIIEKHEKGIKYAHLIQNDKFPIILDANGEVLSLPPIINGTLTKVTPTSKNLLIDITGTEKEAVEETLNIIVCALVERRGTIVSVNVNGKKYPDLTPKSRIISVESINKKLGLNLNPGEIIQALKKSGMDALYEDGNLIVKIPAYRNDILQNVDLKEEIAINYGYEKFDGKLPSVATTGSKDPVEKKCSAMSDLMIGLGFYEVMNLTLSNQDTLFEKMNLKVDEKDYIEVLKPASIEHRVLRTSILPLLLETLYINKHNALPQKIFEVGDCVVIDEEDTETDTKCKNIKKIAGAITHPLTNFNEIKSSTEALLREFFEGFEFENYEHPAFIPGRCAKILKSGKEVGFFGEIHPEVILNFELEHPVVGFEITIE
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C4BPA_MOUSE
Sequence: MCAKQQQTLLPTRAAHGRLHRNRDAVAWPFSTLCRVSGPTLFQMTFTAALWVAVFGKCGPPPAIPNALPASDVNRTDFESHTTLKYECLPGYGRGISRMMVYCKPSGEWEISVSCAKKHCRNPGYLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKGVAWSNPFPECVIVKCGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKTVPVWSSSPPTCEKIICSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRGRHVIECQGNGNWSSLPTCEFDCDLPPAIVNGYYTSMVYSKITLVTYECDKGYRLVGKAIISCSFSKWKGTAPQCKALCQKPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCEQEASEDLKPALTGNKTMQYVPNSHDVKMALEIYKLTLEVELLQLQIQKEKHTEAH
What is the function of this protein?
Controls the classical pathway of complement activation.  It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b.  It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a.  Alpha chain binds C4b.  It interacts also with serum amyloid P component.
What are the official names of this protein?
C4b-binding protein, C4bp.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7S_BARHE
Sequence: MKQEIQKGDVATLSFEQALKQLEVIVENLERGDVPLEQSIDIYERGEALKKHCEKLLKAAEAKVEKIQLSEGGTPEGVEPLDSE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDD_ECOHS
Sequence: MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHSIDRVLLA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: YRAN_SHIB3
Sequence: MATVPTRSGSPRQLTTKQTGDAWEVQARRWLEGKGLRFVAANVNERGGEIDLIMREGWTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: MTBC3_METAC
Sequence: MADIEGLLHEVADAVISCKKEKVLEAVEKARAEVPPEEIIEKGLSAGMNQVGVLFERGKLFLPHVMMAADAMTTGVKLLEADLPAGAEKKLGVIVNGTVEGDVHDIGKSIVSTMLQSAGFEVHDIGRDVPIRDFIEKAKETDADMIGISALMTTTLQGQRDVIELLKEEGLRSRVKVMVGGAPATQAWADKIGADCYAENASEAVAKAKELLL
What is the function of this protein?
Acts as a methyl group carrier between MtbB and MtbA.
What are the official names of this protein?
Dimethylamine corrinoid protein 3.
What is the protein family that this protein belongs to?
Belongs to the methylamine corrinoid protein family.
Protein: DAPB_STAEQ
Sequence: MNILLIGYGAMNQKVARLAEDKGHEIVGVIDRTPKSSTPYSQYKHISECKEADVAIDFSNPELLFPLLEEQFNLPLVIATTGEKETLIQKLETLSQRTPVFFSANMSYGVHALTKILETAVPLLEDFDIELTEAHHNKKVDAPSGTLVKLYDVIKELRDNISPVYDRHEKTEKRTHDEIGIHAVRGGTIVGEHDILFAGTDETITISHRAQSKDIFANGAIGAAEKLIHKNPGFYTFNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPE14_MYCTO
Sequence: MDFGLLPPEVNSSRMYSGPGPESMLAAAAAWDGVAAELTSAAVSYGSVVSTLIVEPWMGPAAAAMAAAATPYVGWLAATAALAKETATQARAAAEAFGTAFAMTVPPSLVAANRSRLMSLVAANILGQNSAAIAATQAEYAEMWAQDAAVMYSYEGASAAASALPPFTPPVQGTGPAGPAAAAAATQAAGAGAVADAQATLAQLPPGILSDILSALAANADPLTSGLLGIASTLNPQVGSAQPIVIPTPIGELDVIALYIASIATGSIALAITNTARPWHIGLYGNAGGLGPTQGHPLSSATDEPEPHWGPFGGAAPVSAGVGHAALVGALSVPHSWTTAAPEIQLAVQATPTFSSSAGADPTALNGMPAGLLSGMALASLAARGTTGGGGTRSGTSTDGQEDGRKPPVVVIREQPPPGNPPR
What are the official names of this protein?
Uncharacterized PPE family protein PPE14.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: NSP6_ROTSH
Sequence: MNRLQQRQLFLENLLVGVNSTFHQMQKHSINTCCRSLQRILDHLILLQTIHSPVFRLDRMQLRQMQTLACLWIHQHNHDLQVMSDAIKWISP
What are the official names of this protein?
Non-structural protein 6, NSP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus A NSP6 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host mitochondrion. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: ATP4B_HUMAN
Sequence: MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLYVLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGYSPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFIIKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK
What is the function of this protein?
The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells.  Plays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump (By similarity).  Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation of the alpha subunit that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2).  Interacts with the phosphorylation domain of the alpha subunit and functions as a ratchet, stabilizing the lumenal-open E2 conformation and preventing the reverse reaction of the transport cycle (By similarity).
What are the official names of this protein?
Potassium-transporting ATPase subunit beta, Gastric H(+)/K(+) ATPase subunit beta, Proton pump beta chain.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type II membrane protein. Cell membrane; Single- pass type II membrane protein. Note=Localized in the apical canalicular membrane of parietal cells.
Protein: NAPB_SHEON
Sequence: MKKILTLAAIVLAIGGCSGQQAETQATPVNIKSLAGDSAVTDIRPADAMPVYPARGKALERSFTDQPPLIPHKDDYKITLDKNGCLTCHSWDKAARMKATPVAKSHVIDDKGTLNGHNYFCTQCHVAQAENKAPLVENKFSTQ
What is the function of this protein?
Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from the membrane-anchored tetraheme c-type CymA protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm.  Not essential for nitrate reduction but confers advantage to the organism when grown on nitrate and thereby a fitness gain in utilizing nitrate.
What are the official names of this protein?
Periplasmic nitrate reductase, electron transfer subunit, Diheme cytochrome c NapB.
What is the protein family that this protein belongs to?
Belongs to the NapB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HXC9_MOUSE
Sequence: MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGDGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C9, Homeobox protein Hox-3.2.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMP_VIBCH
Sequence: MTGLERQLTEMLEAPVVAAGYELVGLEFVRAGQHSTLRIFIDHENGITVEDCAEVSRQVSAVLDVEDPISVVYNLEVSSPGLERPLFKAAHYEQFIGHEVSIVLKMAVGNRRKWKGVIQSIDGETVAVMVDGQEEHFALSNISKANLIPKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METJ_VIBCM
Sequence: MADWNGEYISPYAEHGKKSELVKKITVSIPLKVLKVLTDERTRRQVNNLRHATNSELLCEAFLHAYTGQPLPTDEDLRKDRPDDIPAEAKRLMTEMGIEFESYDE
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD12_DICDI
Sequence: MTIGLEPAVSSKTKDKMEQDLSPIADKSCKENRELAKSGKLIEAIENLLITEKQCRQAEDSPSTSKIAAEIIKLCYEAGRLDLVNEKLVLLSKRRGQLRPAIKAIVQESMVYVDQITDMKQKLELIDTLRTISDGKIFVENERARLTKTLSKIKEDEGDIASAAKILQDLQVETYGTMEKREKITFFIDQMRICMNNKDFIRAQLIGNKVNRKTLAEDENQDLKIDYFKQMIRYFSHSANYIEIARCYLSIYDTPSVEKDTPQLLQTLKYICIYVILSASSNEQSDLLNRVYEFKPLTDIQNYKDLLNQFKTLELIRWSTFFELNKPELDSQTVFKTEPNAWEDLRKRVIEHNIRVISTYYQKISTARLAELLDLSLDESEKFVSDLVSNKTIFAKIDRPAGIATFTTTNDPNKVLNAWANNITSLLDLVEKTNHLVQREFMLHKIN
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 12, 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit p55.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit p55 family.
Protein: RM50_HUMAN
Sequence: MAARSVSGITRRVFMWTVSGTPCREFWSRFRKEKEPVVVETVEEKKEPILVCPPLRSRAYTPPEDLQSRLESYVKEVFGSSLPSNWQDISLEDSRLKFNLLAHLADDLGHVVPNSRLHQMCRVRDVLDFYNVPIQDRSKFDELSASNLPPNLKITWSY
What are the official names of this protein?
39S ribosomal protein L50, mitochondrial, L50mt, MRP-L50, Mitochondrial large ribosomal subunit protein mL50.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL50 family.
Protein: PS1_PSEPD
Sequence: GLNTLKKVFQGLHEAIKLINNHVQ
What is the function of this protein?
Possesses antifungal activity against C. albicans and is also active against E. coli and S. aureus.
What are the official names of this protein?
Pseudin-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Pseudin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AAEA_SALAR
Sequence: MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITHVNVHDNQLVQKDQVLFTIDQPRYQKALAEAEADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYAGEFITRGSTAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSVAAGVTNTSSTSDAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWPAGTTATVVITGKQDRDASQDSFFRKLAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RNPH_BRUME
Sequence: MRPSKRAADEMRTISFERGVSKHAEGSCLVKFGDTHVLCTASLEEKVPGWMRNTGKGWVTAEYGMLPRSTGERMRREAAAGKQGGRTQEIQRLIGRSLRAVVDMQALGEMQITVDCDVIQADGGTRTAAITGGWVALHECLRWMEARQMVRVEKVLKDHVAAISCGIYEGVPVLDLDYAEDSVAETDSNFVMTGKGGIVEIQGTAEGVPFSEEEFGALMKLARSGIDRLVSLQKMAVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: STK35_MOUSE
Sequence: MGHQESPLTRAAAGGAAYIKRLRKVLSWRELGDGHGNLEAEASPGSVAVITRAAPRRATRSARLPASRPTRLCRQARLGTDHPPARAPRGNRFARKRNSAGQITIQGPAPPHLGARRRDEARGARAAPLLLPPPPAAMETGKENGARRGTKSPERKRRSPVQRVLCEKLRPAAQAMDPAGAEVPGEAFLARRRPDGGGGDVPARPRYSLLAEIGRGSYGVVYEAVAGRSGARVAVKKIRCDAPENVELALAEFWALTSLKRRHQNIVQFEECVLQRNGLAQRMSHGNKNSQLYLRLVETSLKGERILGYAEEPCYLWFVMEYCEGGDLNQYVLSRRPDPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGTPILKVADFGLSKVCAGLAPRGKEGNQDNKNVNVNKYWLSSACGSDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDSETKKELLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGVKQLLKDMLAANPQDRPDAFELETRMDQVTCAA
What are the official names of this protein?
Serine/threonine-protein kinase 35, Serine/threonine-protein kinase 35 L1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Cytoplasm. Note=When associated with PDLIM1, it is mostly found in cytoplasm, localized to actin stress fibers.
Protein: TGT_VESOH
Sequence: MKFELKNTNYLARRGKIIFDRGEVETPSFMPVGTYGSVKAMTPEELSSFGTQMILGNSFHLAITPGIDVVQAHGNLHDFMHWKGPILTDSGGFQVFSLGETRKISEKGVDFRSPKDGAKIFMGPEESIQIQKKLGSDIVMIFDECTPYPADKKTVYKSMQLSLRWAQRSKNEHDRLNNKNALFGIVQGGMHEDLRIQSAATLVEIGFNGFAIGGLSVGESKEEMIKVLDYLPSQLPSDKLRYLMGVGTPKDLVEAVERGIDMFDCVMPTRNARNGYLFTSIGIVKIRNARYRLDTSVLDECCHCYTCQNYSKSYLHHLQRKNEILGARLNTIHNLYYYQYLMLQMRRAIESNKFSKFKKEFYQQQGHDTL
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: MTNC_XYLFT
Sequence: MSMPQAILTDIEGTTSSLSFVKEVLFPYARRALPDFVREHREHPDVMPWLDQVANETGTAFSEEALVATLQTWIDTDSKHTALKALQGMIWTSGYQNGDFTAHLYPDAVQRLRAWHAANVPLYVYSSGSVPAQQLFFRHSHAGDLSGLFSGWFDTQIGGKRESTSYQRIAQHIGIAPAGIVFLSDVIEELNAAAQIGLNTVLIDRRDDYPTPRHLKDTDRHLHLDSFAQLPF
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.