PharMolix/UniProtQA huggingface dataset:
Protein: TRPA_ENT38
Sequence: MERYDNAFTELKARKEGAFVPFVTLGDPGPEQSLKIIDTLIAAGADALELGIPFSDPLADGPTIQSATLRAFASGVTPTQCFEMLATVRQKYPTIPIGLLMYANLVFNRGIDEFYAECARVGVDSVLIADVPIEESAPFRQAAMRHNIAPIFICPPNADDELLRQIASHGRGYTYLLSRAGVTGAENKAAVPLHHLVEKLAEYHAAPPLQGFGISSPEQVTAAIEANAAGAISGSAIVKIIEKNVDKPDQMLTELRDFVTVMKAATRHA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: IRC19_YEAS7
Sequence: MRKPSITITTAKAIITPDYTLIKSHSKYQLPSRFQKLDADSPERSTVVKLFYRRFMRLKPFISNVKMVKDTYRDYVRYKFMKENYELKRYLVFNPDGLRSKIKLELLSNTKCCERILPVTEMQRTLEFVLKSCSYLPETKVQKWDIARDNTYCRQILKNLLTMQYEKYRSILHRGIGHDELDVKFSHLKTTSSPLTKLNKTEKKKIPLFKVFSDFDTTLIYLNETLGTRL
What is the function of this protein?
Involved in sporulation and maintenance of the mitochondrial DNA.  Is probably involved in a pathway contributing to genomic integrity (By similarity).
What are the official names of this protein?
Increased recombination centers protein 19.
What is the protein family that this protein belongs to?
Belongs to the IRC19 family.
Protein: MILL2_RAT
Sequence: MEASSGTAGPAVLLLILALLLTESQGSRSQGTHTLRYDVTACFLEGSEQTRLLVLIYVDDELFLRYNGDRRSAKPWACWIKGHGGDETCTREAENLPKEEERLREMMADMINQKGHDKGPYTLQATLDCELQRNGSTRGFWHLGYEGRNLLTFDQKTLTWTMDVPFTQQKKTFEPRAPKADLVKTFLDETCPARLQRHLASLSNVLPDTGSPVVIVTCRNYPVGRITLTCRAFNLSSRVATLLWLRDGKPVQQDVFGPGTILPSGDGTYQTWVSIRVLPGQEPQFACNLRHSNRTIMQTAVSGESMGWPSASWATRQEAEGPHRTHNDHVVDGGLVTGNANKDSPDASSCATASAISAFPVVVLSVALPRAN
What is the function of this protein?
Binds to heparan sulfate proteoglycans on the surface of fibroblast cells.
What are the official names of this protein?
MHC class I-like protein MILL2, MHC class I polypeptide-related sequence B, MHC class I-like located near the leukocyte receptor complex 2.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: QUEA_SHEB2
Sequence: MRVADFSFDLPDELIARYPMAQRNASRLLTLDGNSGALGDKQFTDLLGMINPGDLMVFNNTRVIPARMFGQKASGGKLEILVERMLDDKRILAHVRSSKSPKVDSLILLDGGYQMKMVARHDTLFELELLSELTILEVLEAVGHMPLPPYIDRPDEDADKERYQTVYNQNPGAVAAPTAGLHFDDAMLDALKAKGVNIAFVTLHVGAGTFQPVRVDTILEHKMHSEWANVPQDVVDLIAQTKAAGKRVVAVGTTSVRSLESAARASQGELKAFSGDTDIFIYPGYQFQVVDAMVTNFHLPESTLIMLVSAFAGFDHVMAAYQHAIAQKYRFFSYGDAMFVTKKAH
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAO1_SERP5
Sequence: MELEYESKRPLYIPYAGPILLEFPLLNKGSAFTEEERNHFNLQGLLPDAVETIEEQAERAYRQYQDFKNDSDKHIYLRNIQDTNETLFYRLLDSHLSEMMPIIYTPTVGEACEHFSDIYRRARGLFISYPNRDRIDDMLQNATKQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNPQRLNDPLYMGWRHPRISGDEYHAFVEEFIQAVKRRWPNVLLQFEDFAQNNATPLLNRYRDEICCFNDDIQGTAAVTLGSLIAASRAAGSQLRDQTVTFLGAGSAGCGIAEQIIAQMKSEGLSEDEARARVFMVDRFGLLTDKLPNLLDFQSKLVQKSENLTAWQTQSDAISLLDVVRNAKPTILIGVSGQPGLFTEELIREMHKHCPRPIVMPLSNPTSRVEARPEDIINWTEGAALVATGSPFAPVHYKEQQIPIAQCNNSYIFPGIGLGVLASGATRVTDAMLMAASRALAECSPLATDGHGALLPDIDDIQGVSKCIAMEVGKAAQLQGMAVVTSEEALSKAIEHNFWRPQYRSYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: Y2101_MYCBO
Sequence: MVVCLIGGVAGSLWPRPAGRLRGGCYFAFMGVAWVLLAISAIANAVKGSLWWDIWSLGLLVLIPAVVYGKMRRSRRISSDQDR
What are the official names of this protein?
Uncharacterized protein Mb2101c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MALT_YERPA
Sequence: MLIPSKLSRPVRLQNTVVRDRLLVKLSSAANYRLTLINCPAGYGKTTLIAQWAADQSNLGWYSLDESDNQSERFATYLIAAIQLATGGHCSKSEALSQKHQYANLSALFSQLFIELSNWDGPLYLVIDDYHLITNDAIHEAMRFFLRHQPENLTLIILSRTLPSLGIANLRVRDQLLELGMQQLAFNHHEAQQFFECRLSSPLEQGDSSRLCDEVEGWVTALQLIALSSRQPNSSAQKSAKRLAGLNASHLSDYLVDEVLDQVDSKARAFLLRCSVLRSMNDALIVRLTGEDNGQQLLEELERQGLFIHRMDDSAEWFCFHPLFATFLRQRCQWELALELPELHHAAAEGWMALGYPAEAIHHALAAGDVGMLRDILLQHAWSLFHHSELALLEQCLTALPYPLLVQNPELALLQAWLAQSQHRYSEVNTLLEQAELAMQERKIPVDEILRAEFGALRAQVAINAGKPDEAEKLATDALKYLPMAHYYSRIVATSVTGEVHHCKGELARALPMMQQTEQMARRHEAYHYALWALLQQSEILIAQGFLQAAYETQEKAFELIREQHLEQLPMHEFLLRIRSQVLWSWSRLDEAEEAARKGVEILANYQPQQQLQCLAMLAKCSLARGDLDNANVYIQRCEALQHGSQYHLDWITNADKPRVIHWQMTGDKVAAASWLRQTEKPGMADNHFLQGQWRNIARVQIILGRFDEAEVVLDELNENARRLRLTSDLNRNLLLSNTLYWQTERKGEAQKALIESLTLANRTGFISHFVIEGEAMAQQLRQLIQLNALPELEQHRAQRILKDINQHHRHKFAHFDEIFVDKLLTHPQVPELIRTSPLTQREWQVLGLIYSGYSNDQIANELDVAATTIKTHIRNLYQKLGVAHRQEAVQQAQRLLQMMGYV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: RLMD_SHEFN
Sequence: MAQFFQAKPNKSKQLSAKLSLSVTQLDHLGAGIAQHQGKIVFIPGVLPGETATVQFVEQKKSYAKAKLISIESASVNRIKPHCPHYQQCGGCDLQHMDTNAQREHKQTALVDLISKLSSAKAIDADIVADPIVGEAWHYRRRARLATLFDKNTQRLQLGFRAGNSNKIVSIQQCPVLSESLSALITPLAANLNQLKAKASLGHVELTQADNGNFAVLRVTKVLPASDIRWLTGFAEKHQLNLLLQDDAGQLTQLFPLLPAGDEAIALPYYHLAQEAVRCSFTPGNFVQVNGAINQAMVDQAIEWLDPQSGERILDLFCGVGNFSLPLALKAAEVIGVEGVPEMVQQAKQNAIDNQLDNVTFYHADLSADLSTQTWLGKIDKLLLDPARAGAFESLQWLQKMQPKKVVYVSCNPASLARDSSVLLASGYRIAQVGLVDMFPQTHHIEAMVLFELNI
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: PDXA_SYNJB
Sequence: MSIPRPKLALTLGDPAGIGPEIVLKALADPEVQSCAHITVVGDRQVLEATYRLLRDRSPAPLAHPAGIPMLECDTGFRLQPGCIGQGDADSGAVSFAYLRTAVERTLQGEFQGIVTAPIAKYLWHRAGHRFPGQTEVLAQLSRSEHYGMMFVARSPHSGWQMRVLLATTHIPLGQVPTVLTPERVRTALDLLVGSLRHTFGIPDPVIAVAGLNPHAGEQGQLGSEEKEWLTELLRTYAHAQIWGPLPPDTMWLAPAQAWHGQGSPAVADAYLALYHDQGLIPVKMLAFDRAVNLTTGLPFVRTSPDHGTAFDIAGQGVARCESLKQAILLAAELLGKNPS
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_ACIF2
Sequence: MAGKHEGSGEKTLYCSFCGKSQHEVRKLIAGPSVFICDECIELCNDIVKDEILDDHSEAQDKLPKPMEIRKTLDDYVIGQDVAKKVLSVAVYNHYKRLEHGGKDNEVELDKSNILLIGPTGSGKTLLAQTLARLLNVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQTGIVYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTRHILFICGGAFAGLEKSVSARLEKGGMGFNAPLKRRDKEATAAMLMQNLEPEDLVRYGLIPEFVGRLPILALLEELDEEALISILTDPKNALVKQYQKLFALEGVTLEFRTEALRAIAKKALARKTGARGLRSILEQILLDTMYELPSMSGVKKVVVDAAVVESGTKPLLVYDDAAKVDMSHPA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CAPSD_SPV1C
Sequence: MIKLVLLVAAIAIFGTGFITVIINQFTSAKNIIMDLYNSDTWLIWLFGRMAVLFSHPLMLTISSLYIVGFIVSKTLYS
What is the function of this protein?
May self assemble to form a helical capsid wrapping up the viral genomic DNA.  The virion assembly and budding take place at the host inner membrane (By similarity).
What are the official names of this protein?
Putative capsid protein ORF9.
What is the protein family that this protein belongs to?
Belongs to the plectrovirus ORF9 family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass membrane protein. Note=Prior to assembly, the major capsid protein is found associated with the bacterial host inner membrane.
Protein: CAPZA_KLULA
Sequence: MSEFEKIVRDIVFDSPPEEISLVYDNLQVLSDGQSKQQIASIIQEFNEKHRVPAAKGEERYLVSEYNKSGSKYFDPVNKVLFAVDHITREASDIEEYTSEDATQVQSDLYDELSKYVSNFFPDTAVFNVFKIPESDQYAIIVVSNKKSLGDFWTGYWLSEYVYDVDGDTISGEVSVDAHYFEDGNVRFKSTASLESAQTDSPIVSIKQFENEFEKNLINKFQYMNETQFKGLRRRLPVTRAKINWGQGIGNYRLGRDAAQGA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: GLMU_SACD2
Sequence: MLEIIILAAGKGTRMRSDKPKVLHTLAGKPFLEHVLDRSAELNADKVHVIIGHGADMVREALAGRDVNFVEQTEQLGTGHAVLQVLPHLNPESDTLILYGDVPLTKTDTLAELRAKVSDSSMGLLTVNLADPNGYGRIVRTNGSVTAIVEQKDANPEQLKIDEVNTGVMAVKSAHLAKWLPALSNDNAQGEYYLTDIIAMSSADDIAIETAQPKDEYEVLGVNNRLQQAELERIFQRQVAEELMVAGATLLDPARLDCRGSIEVGRDCVIDVNCVFEGKVVLGNNVHIGPNCVISDSTIGDGTVILANSILEESTLAENCNIGPFARLRPGSQLASKAKIGNFVETKKAVIGEGSKVNHLSYVGDAEIGAGVNIGAGTITCNYDGVNKSKTTIEDGAFIGSNSALVAPVTVGKNATVGAGSIVTKNSEEGDLIIARAKQSNIKGWARPVKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESTJ_MANSE
Sequence: RIPSTEEVVVRTESG
What is the function of this protein?
JH esterase plays a crucial role in the decrease of JH activity in lepidopteran insects, by hydrolyzing the methyl ester of JH.  It is also involved in the transport of JH.
What are the official names of this protein?
Juvenile hormone esterase, JH esterase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
Protein: ATPG_CAMJD
Sequence: MSNLKEIKRKIKSVHNTQKTTNAMKLVSTAKLKKTEEAAKRSKIYAQKIDEILSEISFQINKIVHNEDDMRLSLFHKKEQIKTVDLIFITADKGLCGGFNIKTLKTVSEMLKEYEAKNINIRLRAIGKTGIEYFNFQKIELLEKYFHLSSSPDYEKACEVIHAAVDDFLNGNTDEVILVHNGYKNMITQELKINHLIPVEPKSIEQTHNSLLELEPEGIELLEDLMKTYFEYNMYYALIDSLAAEHSARMQAMDNATNNAKARVKQLNLAYNKARQESITTELIEIISGVESMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CHEB_COLP3
Sequence: MAYKVLVVDDSSFFRRRVTDILNKDPKLNVIDVAVNGQEAVDKALLLKPDVITMDIEMPILNGIEAVRKIMAQSPTSILMFSSLTHQGAKATLEALDAGALDFLPKKFSEIAKNSDEAGSLLRQRVVEIARKSEFSKQRTRTRPAAVNISPKSSRLIADQHRPLASTSSLVTKDKKVMAAITRSSGKEYKLLAIGTSTGGPVALQKILVQLEENFPLPIIIVQHMPAAFTAAFASRLNSLCKISIKEAADGDVLKPGCAYLAPGGRQMLISGSENSAKIKILDDDSPKITFKPSVDISFGSAAKTFAGKVLGVILTGMGSDGKEGARMLKAKGATIWSQDEQSCVVYGMPQAIDKAGISELSLSLDSMAASMVKEISRG
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDB_CONDE
Sequence: MSGMGVLLLVLLLVMPLAAFHQDGEGEATRRSGGLKRDCPTSCPTTCANGWECCKGYPCVRQHCSGCNHGK
What are the official names of this protein?
Conotoxin De13.1, de13b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin G superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURB_ALKCK
Sequence: MKRYIEICKPLWTLLPEGTIHEDERLCKHTYTQMGGAADLFITPQSYEETQTVLKFAHEHRVPVTLLGNGSNVIVKDGGIRGITLSLKKLNTITCTGVELVAQTGATIIEASRRARDAELTGLEFACGIPGTVGGAFYMNAGAYGGQIADVLESVLVLTEQGEFKTLSKEEFDFDYRKSVFSAKRYIALEGTFRLQKGDMAQIQAKMDELTIARETKQPLEYPSCGSVFKRPPGMFAGKLIQDSGLQGTRIGGAEVSKKHAGFIVNVDNATATEYMSLVRHVQQTVKDKFGVELETEVITIGEDIEEPVSD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P20D1_ASPOR
Sequence: MKATDLFHVTALVAGALALEHQQPLIGDLSQDLNHIIDSSPLLSFHRALVQIPSISEHEKNVGEYVLDFLSSQNLTVEKQIVTPESDTEEERFNIYAYVGKNRQPDVLVTSHIDTVPPFIPYSLHAPTSGTSFIRTDLVIAGRGTVDAKASVAAIVFAALETLDENPNASIGLLFDVGEENSGVGMKHFSNSELNPTPPTYHTVIFGEPTELSLVAAHKGTLGFKLVAEGKAAHSGYPWLGESAISSLIPVLAHLDTLQDLPPEKGGLLRSETLGKSTLNIGRVHGGIAANVVPAHAEAAISVRLAAGTPEDTRTIIERAVAKVTSGDRSVYPDFGDRKAGAPPQYFDVDVDGFEVITVNYGTDAPALKIHDQRTQRVKRYLYGPGSILVAHADNEAITVGELEEAVRGYKRLIAASL
What are the official names of this protein?
Probable carboxypeptidase AO090166000075, Peptidase M20 domain-containing protein AO090166000075.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVC_HALH5
Sequence: MAKVFYNGDINEGVLQGKTVAIIGYGSQGHAHAQNLRDSGQEVIVGLRPGKSWDKAAEDGFQVYSVREAASRADVIMILLPDEHQPTVYKNEIEPELSEGKTLAFAHGFNVHFNQIVPPATVDVFLAAPKGPGHLVRRTYVDGAGVPGLVAVYQDATGQAKDIALAYSKMNGSARAGVIETTFQEETETDLFGEQAVLCGGTSALVKAGFETLVEAGYQPEVAYFECLHELKLIVDLMYEGGLEYMRYSISDTAQWGDFQAGPRVVTAETKQAMKDILSDIQTGKFAKGWILENQANRPEFTAINEREKNHPLEVVGRELREMMPFVKAKSKGVVGSAKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: VATD_ARATH
Sequence: MAGQNARLNVVPTVTMLGVMKARLVGATRGHALLKKKSDALTVQFRALLKKIVTAKESMGDMMKTSSFALTEVKYVAGDNVKHVVLENVKEATLKVRSRTENIAGVKLPKFDHFSEGETKNDLTGLARGGQQVRACRVAYVKAIEVLVELASLQTSFLTLDEAIKTTNRRVNALENVVKPKLENTISYIKGELDELEREDFFRLKKIQGYKRREVERQAANAKEFAEEMVLEDISMQRGISINAARNFLVGGAEKDSDIIF
What is the function of this protein?
Subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit D, V-ATPase subunit D, Vacuolar H(+)-ATPase subunit D, Vacuolar proton pump subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: DHA1_STAAN
Sequence: MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLEDMYAEKDVTVVKSTPENLAEQIKKADVFISTILIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE
What is the function of this protein?
May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer.
What are the official names of this protein?
Alanine dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
Protein: SLA2_MACLB
Sequence: MGRLISVSFGLLVVFLSLSGTGADQDCLPGWSSHEGHCYKVFNLDKTWEDAEKFCTEQANSGHLVSIDSKKEANFVAELVSQNIKETRRTDFVWIGLRAEDKRQHCSSEWSDGSSINYQNWIEAESKKCLGLEKQTRYRKWVNLNCGQPYRFTCEI
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec A2, C-type lectin A2.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: KATG1_BURO1
Sequence: MSNETKCPFNHTAGSGTTNKDWWPNQLNLNVLHRHSALSDPMDPDFDYAEAFKKLDLAAVKQDLHALMTTSQDWWPADFGHYGGLFVRMAWHSAGTYRTADGRGGAGGGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGRNISWADLLILTGNVALESMGFKTFGYAGGRADTWEPDDVYWGSEKIWLELSGGPNSRYTGKRELESPLAAVQMGLIYVNPEGPDGNPDPVAAAHDIRETFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGPEPEAAGLEEQGLGWKSTFGTGKGKDTITSGLEVTWTSTPTKWSNDFFKHLFSYEWELTKSPAGAHQWVAKDAGEVIPDAYDASKKHRPTMLTTDLSLRFDPAYEKISRRFYENPAEFADAFARAWFKLTHRDMGPRARYLGPEVPAEHLLWQDPIPAVDHPLIDAADVAALKAKVLATGLSVSQLVSTAWASAATFRGSDKRGGANGARIRLAPQKDWEVNQPAALATVLETLEGVQKAFNDAQTDGKKVSLADLIVLAGAAGVEQAAKNAGIAISVPFAPGRMDASQEETDVDAMAVLEPVADGFRNYLKSAYKTPAEALLVDKAQLLTLTAPEMTVLVGGLRVLGANVGDSKHGVFTDRPGTLSNDFFANLLDMGTEWKPVSAANDVFEGRDRATGAVKWTGTRVDLIFGSHSQLRALAEVYGSADAQEKFVRDFVAAWNKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: KIBRA_DROVI
Sequence: MSNQQQQQQQQQQPRQHPQPHPHHHHHHLHHHHQQQPGQHSEFPLPEGWDIARDFDGKTYYIDHINKKTTWLDPRDRYTKPQSFEDCVGDELPVGWEEAYDSNIGRYYINHIAQSTQLEDPRQEWKSVQEQMLSDYLSAAQDQLENKREMYDVKQQRLNLAQEEYNHLNKLAASRSSLCSSSSSMSRHDPELLRADLMLARERVRQLKQELTHITNDISYTERGMNTLYSVGEKINARKNGCYDIAEVQAIREEMLKVHKSLVSGEKVREELMRSLVQIKNELSRQQINEENAELMSAASPFDRVCVASQTDLCGAGEHLNGGARFAEMAKTKLQYAEWRKHIKKLQQQLADHVERIEPGQLESDKDRILLIQEKEKLLNDLNSISLKSRSAEEKQVIQQTRHKLEEDLKEAYEATNTCIANRLRFHEEKQLLLDKLQEALKSTKLLEERLKSFSSESTFSISSGSSLGSLSTASSKSALSFTDIYIDPFAVGESPIDVVDLQRRSQRLFQQHQRLPPVHPALQQQQQTQPLASSEVSLSPRSSLSMETPPASPMKYNAVADQPQAQAKLKEEPTYANALPALPTIPAPPAYAAPPAIPLALAAVRAHPYDLDSTVLDCMMLEAKLQKLNLGSPLNLNGPLSPISEKPSLLDLPQEMLSRSSSTSNTRSVSAAVSNESVAGDSGVFEASRAHLPRKELAQVQIGLKYLKQEGVLVVSLERANNLSALWTATTDNSQVYLRAALLPNSLTSIRTKALSDFQKPVFNDTFAVPISLDKLLTKSLQVTVVSMTGQKEEIIGTVQISMAEFNPEDSTLKWYNVLSSKFIPSFESLDLPSTSAAAAAAAVAASNSNNNNSNTNNREESSDESTITSSQTSTLTRNQAPPLELQAQIAEELPEHVRHNEQQCSDDDDDDDEEEDEQQLVGTLGLTHSGCMLDAYLENMKQEYADKETNTDCAFPPEKLRSQSQLLDDRPVKRSQTFTPSAAVSKNRYNCRLNRSDSDSAMHFGVTPHTFHRGAVERRSLRFQPKATKSVTKLHHNHIPRTSLDLELDLQAQHSKLFFLNDQISKLQNLKEVLQKACDNKDPLIAAWAIENEEFQRLVARADPAKFPEERLLQKLLMKTTKEIHKLRKTKVPKGAPDLVSFKEKISFFTRKGMSVPELPIEFMHPDADAIEEEEEDDNDDEEDNVVETAIAINTALVASSNRNKNLSEHHHRSTDGALSKLAATLTPAINPAPVSAPIPVAVSVPVAAPLADEAKPEQQRYDYVVDRNYGVEV
What is the function of this protein?
Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein.  Kibra acts synergistically along with Ex and Mer to regulate the Hippo signaling pathway (By similarity).
What are the official names of this protein?
Protein kibra.
What is the protein family that this protein belongs to?
Belongs to the WWC family. KIBRA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Apical cell membrane. Note=Localizes at the apical cortex of epithelial cells and cytoplasmic, punctate.
Protein: TX2M2_LYCSI
Sequence: MIKYVLISALLVVAVYSFTIEDNEDALLEEAEDELDTEEERRMALPPGAVCNGHKSDCQCFGAKYKCSCPFLWRFRRSAECHCKKGWAWTAIKKRSCHNRYQWSG
What is the function of this protein?
Insecticidal to house crickets.  It induces an excitatory slow-onset impact that leads to irreversible spastic paralysis.  It also modifies human voltage-gated potassium channel Kv1. 5/KCNA5.  Most likely, it binds to the voltage-sensing domain of the channel, suggesting it does not block the pore but prevents its opening at physiological membrane potentials.  The recombinant peptide binds to the channel in an irreversible manner and slows down the hKv1. 5 current activation kinetics.  It is not toxic to mice, when intracranially injected (at 0. 5 ug/g mouse).
What are the official names of this protein?
U2-lycotoxin-Ls1b, U2-LCTX-Ls1b, Toxin LSTX-M2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 04 (omega-agtx) family. 01 (type I omega-agtx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR5_STAEQ
Sequence: MSKAYEESGVNIQAGYEAVERITSHVERTLRKEVLGGLGGFGATFDLSQLKMKAPVLVSGTDGVGTKLKLAIDYGKHDTIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPSTIEQIVKGISDGCEQTNTALIGGETAEMGEMYHEGEYDIAGFAVGAVEKEDYIDGSNVEEGQAIIGLASSGIHSNGYSLVRKMIKESGVQLHDQFNGQTFLETFLAPTKLYVKPILELKKHIDIKAMSHITGGGFYENIPRALPKGLSAKIDTQSFPTLEVFNWLQKQGNISTNEMYNIFNMGIGYTIIVDKKDVQTTLTTLRAMDTTAYEIGEIIKDDDTPIHLLEVE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.