PharMolix/UniProtQA huggingface dataset:
Protein: CLPX_KLEP3
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRHHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFSLEGAELEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMDDVEKVVIDESVIEGQSKPLLIYGKPEAQQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: AIS_ECO81
Sequence: MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRFLQCGNEIYSAIKDLQRKAPDKNIVIFTHNHCLTYIAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: UBID_ECOL5
Sequence: MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIWLDRTLRAGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGYIEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRM5_PLAKH
Sequence: MFYGFLLLYPLLSLCLEHVISLSKKGKPTLGFVIMRNAVDIKTLSDVKDRVKNEKRTHCLVVNKYKVNDVLKNKEAKFYFLNVFRFPSVLKLREYEGNLMETGQYNGEVLRFIHSYVERLGGGGTHVGGKADSKADGKVNHDVSDQVVAQQTDQQMDQQMDQQTDQQMDQQMDQKRDAALEDCRLIPLNARFNKALQELMQREGKEIMEGLDMHLEEGDAGNVTVEGVAMEDDSTAHDSVQRNEGKTPKGPLDGQWPPLEELFRIIKKEGIQISIIQLQFGYDNMNTSEILRKIFPTESEVIHKYEMIGHIAHLNFCERFENYKKVIAEIILDKNKSIKTVINKMDTLKNLHRTFNIELLAGEKNYLTTLKENDIKVKLNYELIYWNSKLKKERDRIYDLVENNSIIVDLFAGVGIFSLHLSKKKCLCFSNDINSHAYNFMNVNIKLNKRKSILTYNLDARAFVQMLLGLDIFSSDKTTLSMQLSEQNWKNISLDFINSPDQNNVDTGKRKKRESDRVGHVDDDITANATIDKKKKLRHADTNDPLEERPLGLAATHHGEENIQSVERTNNDSEKTKEDAPRDVTHQVDINLGIYGDIHVLMNLPQTAFEFLDIFRELLDTYSTDQKDFQGKCRRDQMRNVFIHCYFFSKPELFYEDAERNIRMQLGGLPREMKITEIRKVSPSKLMYVAEFNLKDVF
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: Y2355_METFK
Sequence: MAGHSKWANIQHRKGRQDAKRGKIFTKLIKEITVSARMGGGDVNFNPRLRAAVAEAKEQNMPAENIIRAIKRGTGELEGVNYEEIRYEGYGINGAALIIDCLTDNKQRAVADVRHVLSKHGGNLGTDGCVAFMFKHCGVLVFEPGTSEDQVMEAALEAGAEDVITDEDGSIEVITAPGDFTAVKEALEAAGLKPVLAEVTMKPDNETVFSGEDGVKMQKLLDALEDLDDVQEVYTTAVIEE
What are the official names of this protein?
Probable transcriptional regulatory protein Mfla_2355.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAGP_KLEP7
Sequence: MLRRFSLFSLGFLGWLLVSGNASASFSSTLSEGYHTLSNNVAQTWNEPEHYDLYVPAITWHARFAYDKEKTDKYNERPWGAGFGVSRWDEKGNWHGLYLMAFKDSFNKWEPIGGYGWEKTWRPLTDQNFHLGLGYTLGVTARDNWNYIPIPVILPLASIGYGPATFQMTYIPGTYNNGNVYFAWARFQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: SYC_LACJO
Sequence: MKVFNTLTRKKEEFKPLVAGKVSMYVCGPTVYNYIHIGNARSVIAFDTIRRYFEYRGYDVNYVSNFTDVDDKMINEARKEHTTVEKLAERYIKAFMEDTEALNIEPATLHPRATHEIKEIIDFVQDLIDKGVAYEVDGDVYYRARKFPNYGQLSDQNIAELEEGASEHINEEEQSKKEDPIDFALWKAQKEEDEIAWDSPWGKGRPGWHIECSVMSTKYLGDTIDIHGGGQDLEFPHHENEIAQSEAKTGKKFVNYWMHNGFVTVGKKQEKMSKSLHNFVTVHDILKQIDPQVLRFYMSSVQYRRPINYSEDGLKQAETVLKRYQNTLRNLDARLNDENETLEDNGLRDDLTQAKAEFIEAMDDDFNVQNALSIMYDLATTLNNHLQKDQVDKPALKRAKKLLIAWLEIFGVSFKEEQAENDDEIEKLIAQRDEARKNKDWAESDRLRDELQAKGIVIEDTPQGTRWHRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_PSEA7
Sequence: MMRILLFLATNLAVLVIASITLKLLGVDRFTGQNYGSLLVFCAVFGFAGSLVSLFISKWMAKMSTGTEVISQPRTRHEQWLLQTVEELSREAGIKMPEVGIFPAYEANAFATGWNKNDALVAVSQGLLERFSPDEVKAVLAHEIGHVANGDMVTLALIQGVVNTFVMFFARIFGNFVDKAILKNEDGPGIGYFVATIFAELVLGILASIIVMWFSRRREFRADAAGAHLAGTGAMIAALQRLRSEQGVPVQMPDTLNAFGINGGLKHGLAGLLMSHPPLEDRIEALRASAR
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSMF1_MOUSE
Sequence: MAGLEVLFASAAPSMSCPQDALVCFLHWEVVTNGYYALGTGDQPGPSDKKSELLPAKWNSNKELYALRYESKDGARKLLLKAVSVENGMIINVLELGTQQVADLTLNLDDYIDAEDLSDFHRTYKNSEELRSQIRSGIITPIHEQWEKARANSPPREFPPATAREVDPLQISSHRPHTSRQPAWRDPLSPFAVGGDDLDPFGCQRGGMIVDPLRSGFPRVLIDPSSGLPNRLPPGAVPPGARFDPFGPIGTSPSGPNPDHLPPPGYDDMYL
What is the function of this protein?
Plays an important role in control of proteasome function.  Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome.  Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28 (By similarity).
What are the official names of this protein?
Proteasome inhibitor PI31 subunit.
What is the protein family that this protein belongs to?
Belongs to the proteasome inhibitor PI31 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: GLT5_WHEAT
Sequence: MAKRLVLFVAVVVALVALTVAEGEASEQLQCERELQELQERELKACQQVMDQQLRDISPECHPVVVSPVAGQYEQQIVVPPKGGSFYPGETTPPQQLQQRIFWGIPALLKRYYPSVTCPQQVSYYPGQASPQRPGQGQQPGQGQQGYYPTSPQQPGQWQQPEQGQPRYYPTSPQQSGQLQQPAQGQQPGQGQQGQQPGQGQPGYYPTSSQLQPGQLQQPAQGQQGQQPGQAQQGQQPGQGQQPGQGQQGQQPGQGQQPGQGQQGQQLGQGQQGYYPTSLQQSGQGQPGYYPTSLQQLGQGQSGYYPTSPQQPGQGQQPGQLQQPAQGQQPGQGQQGQQPGQGQQGQQPGQGQQPGQGQPGYYPTSPQQSGQGQPGYYPTSSQQPTQSQQPGQGQQGQQVGQGQQAQQPGQGQQPGQGQPGYYPTSPQQSGQGQPGYYLTSPQQSGQGQQPGQLQQSAQGQKGQQPGQGQQPGQGQQGQQPGQGQQGQQPGQGQPGYYPTSPQQSGQGQQPGQWQQPGQGQPGYYPTSPLQPGQGQPGYDPTSPQQPGQGQQPGQLQQPAQGQQGQQLAQGQQGQQPAQVQQGQRPAQGQQGQQPGQGQQGQQLGQGQQGQQPGQGQQGQQPAQGQQGQQPGQGQQGQQPGQGQQGQQPGQGQQPGQGQPWYYPTSPQESGQGQQPGQWQQPGQGQPGYYLTSPLQLGQGQQGYYPTSLQQPGQGQQPGQWQQSGQGQHWYYPTSPQLSGQGQRPGQWLQPGQGQQGYYPTSPQQPGQGQQLGQWLQPGQGQQGYYPTSLQQTGQGQQSGQGQQGYYSSYHVSVEHQAASLKVAKAQQLAAQLPAMCRLEGGDALSASQ
What is the function of this protein?
Glutenins are high-molecular weight seed storage proteins of wheat endosperm.  Thought to be responsible for the visco-elastic property of wheat dough.
What are the official names of this protein?
Glutenin, high molecular weight subunit DX5.
What is the protein family that this protein belongs to?
Belongs to the gliadin/glutenin family.
Protein: MURC_ECOSM
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEFPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYDDFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEMLAPVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FENR_ALBFT
Sequence: MRNHQDPIETDAVIVGAGPVGLFQVFELGLLEIKAHVVDSLAYPGGQCIELYPDKPIYDIPAVPVCTGRELTQNLLKQIAPFGATFHYGQEVTVVEKQSDGRFFVETSKGTRFLSKTIFIAAGVGAFQPRTLKVDGLEVFEDSQLFYRVRNPADFADKNLVIVGGGDSALDWALDFVKDGPNKAASVILIHRRDGFKAAPASVAKMRELCDALEMQFIVGQVTGFEAQDSLLTGIKVTGADGVTRVVPLDVLLVFFGLSPKLGPIAEWGLDIERKQLKVDTEKFSTSEPGIFAVGDINIYPGKKKLILSGFHECALAAFGAMPIISPEKKVFLQYTTTSPKLHKVLGVESPVFD
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RL20_AERS4
Sequence: MPRVKRGVTARARHKKVMKAAKGYYGARSRVYRVAVQAVTKAGQYAYRDRRQKKRQFRQLWIARINAAARQNGLSYSRLINGLKKASIEIDRKILSDIAVHDKLAFTALVEKAKAALV
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RPOB_YERE8
Sequence: MVYSYTEKKRIRKDFGKRPQVLDIPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVKECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNFTTAQILDLFFEKVVFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKARRITARHIRQLEKDGIDRIEVPVEYIAGKVVAKDYIDENTGELICAANMELSLDLLAKLSQAGHKQIETLFTNDLDHSAYISETLRVDPTSDRLSALVEIYRMMRPGEPPTREAAENLFENLFFSEDRYDLSAVGRMKFNRSLLRDEIEGSGILSKEDITEVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRRVRDGVVTDEINYLSAIEEGNFVIAQANSNLDEDGRFIEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTSVAKRGGTVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVNLGEPIERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLTEELQILEAGLFARIHAVLVSGGIEADKLSKLPRDRWLELGLTDEDKQNQLEQLAEQYDEMKSEFEKKMDAKRRKITQGDDLAPGVLKIVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGEKINAMLKKQEEVAKLREFIQKAYDLGDSVCQKVDLSTFTDDEVLRLAENLKKGMPIATPVFDGATEKEIKELLQLGGLPTSGQITLFDGRTGEQFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLLKEIRSLGINIELEEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL19_ACIF5
Sequence: MNIIDEINQEQMQSVLPAFGAGDTVAVHVKVKEGDRERVQIFEGICIARRNRGLHSAFTVRKISNGEGVERVFPSYSPLVTKVEVKRRGDVRRAKLYYLRDLSGKAARIKEKLG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: FEN1_DROWI
Sequence: MGILGLSKLIADLAPQAIRESEIKNFFGRKVAIDASMCLYQFLIAVRSEGAQLATVNGDPTSHLMGMFYRTIRLLDNGIKPVYVFDGKPPDLKSGELAKRAERREEAEKALKAATEAGDEAEIEKFNRRLVRVTKEHAREAKELLKLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTFGSSKLLRYLTYSEARKMPVKEFTYEKLLQGLELNQREFIDLCILLGCDYCESIKGIGPKRAIELINSYRDIETILDNLDTSKYTVPENWNYKVARELFIEPEVADASAIDLKWTEPDEEGLVKFLCGERQFSEERVRGGAKKLLKSKKAQTQVRLDSFFQTLPSSPNAVAAAKRKAEEAKKSANNKKAKIGGGGGAGRGRRPK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: MPA54_PHAAQ
Sequence: AKYDAFIAALTEALRVIAGAFEVHAVKPATEEVPAAKIPAGELQIVDKIDAAFKIAATAANSAPANDKFTVFEGAFNKAIKERHGGAYETYKFIPSLEASRSKQAYGATVARAPEVKYAVFEAGLTKAITAMSEAQKVAKPVRSVTAAAAGAATAAGGAATVAASRPTSAGGYKV
What are the official names of this protein?
Major pollen allergen Pha a 5.4, Allergen Pha a 5.
What is the protein family that this protein belongs to?
Belongs to the Poa p IX/Phl p VI allergen family.
Protein: RITA1_MOUSE
Sequence: MKALHLQHRSPTSYRVKARASYVDETLFGSPARTRPAQPDFDPPWVQNCNRSRGVGPGPPKGSLAKRDCESPSSRGSTPNLTPRKKNKYRLIGHAPSYCDESLFGTSKEGSRMAVGDAAKLRTLFWTPPATPRGSHTPCPRETPLRAIHPAGPSRTEPRVTAGSQMSSQDGLCVPCSLGQRRSHSLTHLTVPSTGHPASSAPQTNGPWSPRPNTSGATVQSPLVTSKACSGRVSGPAPPRRGACPPKPKPPWK
What is the function of this protein?
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway.  Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription.  May play a role in neurogenesis (By similarity).
What are the official names of this protein?
RBPJ-interacting and tubulin-associated protein 1, RBPJ-interacting and tubulin-associated protein.
What is the protein family that this protein belongs to?
Belongs to the RITA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear (By similarity).
Protein: PVK3_CYRPO
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, CyrPo-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRH_CHLTA
Sequence: MMKKRVKRVLFKISGEALSDGDSSNRISEERLSRLIAELKVVRNADVEVALVIGGGNILRGLSQSQSLQINRVSADQMGMLATLINGMALADALNTEDVPNLLTSTLSCPQLAELYNPQKASDALSQGKVVICTMGAGAPYLTTDTGAALRACELKVDILLKATMHVDGVYDQDPRECADAVRYDHISYRDFLSQGLGAIDPAAISLCMEAGIPIKMFSFARHSLEEAVFNTVGTVISSAEGGQL
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IEND1_NEUCR
Sequence: MIKKMKSYINMNSTVTTLGANYLVHTGYFNTISRLKVCTIASYRYYSTSKSDSQSSDLPPVPIFTINNLNNKDSIKSSRILLKDKGGIYSFINTVNNNQYIGSAKDFYLRLNEHLENKKSNIALQKAFTKYGLDKFIFCIYEYFTYESKIISHKALTDLETSYINRFNFDNLYNFKAIATSSLGYKHTEEARLKMVDYYKDKNNHPMFGKTHTEEALGLISKPGELNPMFGKKHSEATKASMSEKKNKYPLGVGIYDLEDNLILKFSNNVELAKYLGISKVTVGKYLNSGLVYNKTYRFKPIQD
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded endonuclease 1.
What is the protein family that this protein belongs to?
To endonucleases of group I introns of fungi and phage.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPG_YERP3
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQERMAASRPYAETMRSVIGHLALGNLEYKHPYLEERDVKRVGYLVVSTDRGLCGGLNINLFKRLLAEMKGWSEKGVECDLALIGSKAASFFGSVGGKIVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVNNKFINTMSQEPRIMQLLPLPPAEDGELKKKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVGGASAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PQQE_RHOPA
Sequence: MLEKSGSVAETFGIPLAVLLELTHRCPLQCPYCSNPLELERGGAELSTDEWKRVLSELARIGVLQVHFSGGEPTARKDLVELVRHATEVGLYTNLITSAVLLSRERLAALADAGLAHVQISFQGSEATIADRVGGFAGGHAKKLDVARWTRELDLPLTVNAVMHRQNLHLLPDIIELALALDADRLEVANVQYYGWALKNRAALMPTLAQIEDCTATVEAARERLKGQLAIDYVIPDYYAARPKKCMGGWGRQFFNISPSGKVLPCHAAETITGLDFPSVRNGASIAEIWRSAEAFNRYRGTGWMQQPCASCAFKEIDFGGCRCQAFALAGDAAATDPACALSPLHDRIFKTAEAEAASGSDRFLYRNFAGGTVEGA
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: PRP40_SCHPO
Sequence: MSAPPWQTSEYDETEGFTSNQEGPSAAPSKTVASDWHEVKTEDSRVYYYNSVTRKSVWEKPEELMNDFEKKLSKLAWKEYATADGKKYWYNVNTRESVWDIPDEYKAALVDEPEQQKKALSSKIKSNDNKPAVQSIQRHGPDVAAPSSQPAKDQSQQISQGSHKRTINFVQQKDKRQKRSNDYQHENYDTYEAAERAFFKFLDSHNVNPSWTWEQTVRELCDAKGYYVMKDPWHRKCAFDAYILNYLTDQSDAEKNRVTKIRKEFIEMLKSSDKIHSYTLWRTVKNEFSSHPAFNATSSETEQQQLFFEYKQKLLEDEKQLEKDRRKEALDDFCSLLRNMNFEPYTRWSVAQAKFDQDPRYTRNSNMKYLSKLDALVAFEDHVKHLEREYILDKQKQKKEKHRIERKNRDAFRALLQDLRVQKKITLRTKWKELYPIIKDDPRYLNLLGQSGSTPLDLFWDTIVDLENMYREKRNLVLDCLEVLQISVDDTSNIPEIIARLSEKLKDREESEAVTEDLIEEVVNRLRDKAIHKKAEEKRADERRIRRKIDNLRSAIKYLKPPISADASYDEIRPLISILPEFAALHSEEHRMAAFDKYIRRLREKRELEKQYQNRRGYYDVGKDESYLANSARPHSGYEDGRLEYSADLASKSNRNEINTMQDVQENSISHVTATQPAVKNIVDDAESSEEGEIR
What is the function of this protein?
Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing.  This protein is associated with snRNP U1 (By similarity).
What are the official names of this protein?
Pre-mRNA-processing protein prp40.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_STRGG
Sequence: MANIKSQIKRNKTNEKARLRNKAVKSSLKTAIRKAREAVVAGDVEKATTAVRDASRQLDKAVSKGVIHKNAAANKKSALASKVASLQA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: FABA_SHEB2
Sequence: MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMMDRIVTINDNGGEFGKGEIVAELDINPDLWFFDCHFITDPVMPGCLGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDLKVGVFSDTSTF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_PSEA6
Sequence: MKFVDEAEIRVEAGDGGAGTVSFRREKYVPDGGPDGGDGGDGGSVYLVADENLNTLIDYRFERFHRAERGKNGQSADCTGRKGADLEVKVPVGTRATDTETGELLGDLTKHGQRLKAAQGGYHGLGNARFKTSTNRAPRQKTLGTPGDVRMLKLELMLLADVGLLGMPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVRLDAMSSFVIADIPGLIEGASEGAGLGIQFLKHLERCRVLLHLIDLMPADGSDPVDNAKAIVTELEKYSPKLAAKPRWLVFNKVDLMFEDEAQDLCKKIADAMNWEGEYYSISAVQGKNTKELCIKVMDFIESLPEDAIEESDDEEVGFKWDTYHKETVENYEDDDDFDDDDDDDFDGDDDDDFDGDDDFEVIYQK
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_SHISS
Sequence: MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.