PharMolix/UniProtQA huggingface dataset:
Protein: NMD3B_HUMAN
Sequence: MEFVRALWLGLALALGPGSAGGHPQPCGVLARLGGSVRLGALLPRAPLARARARAALARAALAPRLPHNLSLELVVAAPPARDPASLTRGLCQALVPPGVAALLAFPEARPELLQLHFLAAATETPVLSLLRREARAPLGAPNPFHLQLHWASPLETLLDVLVAVLQAHAWEDVGLALCRTQDPGGLVALWTSRAGRPPQLVLDLSRRDTGDAGLRARLAPMAAPVGGEAPVPAAVLLGCDIARARRVLEAVPPGPHWLLGTPLPPKALPTAGLPPGLLALGEVARPPLEAAIHDIVQLVARALGSAAQVQPKRALLPAPVNCGDLQPAGPESPGRFLARFLANTSFQGRTGPVWVTGSSQVHMSRHFKVWSLRRDPRGAPAWATVGSWRDGQLDLEPGGASARPPPPQGAQVWPKLRVVTLLEHPFVFARDPDEDGQCPAGQLCLDPGTNDSATLDALFAALANGSAPRALRKCCYGYCIDLLERLAEDTPFDFELYLVGDGKYGALRDGRWTGLVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRARDTASPIGAFMWPLHWSTWLGVFAALHLTALFLTVYEWRSPYGLTPRGRNRSTVFSYSSALNLCYAILFRRTVSSKTPKCPTGRLLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEAYIKKSFPDMHAHMRRHSAPTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPCGKRVFAVTETLQMSIYHFAGLFVLLCLGLGSALLSSLGEHAFFRLALPRIRKGSRLQYWLHTSQKIHRALNTEPPEGSKEETAEAEPSGPEVEQQQQQQDQPTAPEGWKRARRAVDKERRVRFLLEPAVVVAPEADAEAEAAPREGPVWLCSYGRPPAARPTGAPQPGELQELERRIEVARERLRQALVRRGQLLAQLGDSARHRPRRLLQARAAPAEAPPHSGRPGSQE
What is the function of this protein?
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium.  Mediated by glycine.
What are the official names of this protein?
Glutamate receptor ionotropic, NMDA 3B, GluN3B, N-methyl-D-aspartate receptor subtype 3B, NMDAR3B, NR3B.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3B/GRIN3B subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane.
Protein: YPOB_STYLE
Sequence: MSQLVREFGKDNKSLKEVTESLAQFVSGLERQECAICFGWGHLANSVPPKPPLIRPAGVTLSGKLSGGLSRPSTSLNQLLLGPTRLRCHPGPAMGGRRSGGRICLGDPGAAAIPTTTTAPTATHQPNQQRQQVIPQQMHGLARQYQRSNLVGNVAQYPFGSVANPIQQLISQFLSFYNSQSQYILLIHTKLDRKLHFVDQTGSF
What are the official names of this protein?
Uncharacterized 22 kDa protein in overamplified macronuclear DNA POB4.
Protein: DKSA_ECO57
Sequence: MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRILEAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKTLKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG
What is the function of this protein?
Transcription factor that acts by binding directly to the RNA polymerase (RNAP).  Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.  Also required for regulation of fis expression.
What are the official names of this protein?
RNA polymerase-binding transcription factor DksA.
What is the protein family that this protein belongs to?
Belongs to the DksA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_VIBCH
Sequence: MSRVAKAPVAIPAGVEVKLNGQEITIKGAKGELTRVFHNGVVIAQEDNQLTFGPREGVANAWAQAGTARALVKNMVVGVTEGFTKKLVLKGVGYRAAMKGNAVGLTLGFSHPVEHELPAGVKAECPSQTEIVLTGCDKQVVGQVAADIRSYRAPEPYKGKGIRYADENVRSKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CLPX_ACIB5
Sequence: MSEHPQGQKHCSFCGKTQSEVGKLIAGEDAYICNECVDVCLDLVQTSQQVEAGDWASKALPKPHEIRAALDQYVIGQDLAKKTLSVAVYNHYKRLKVGQSGHVSKDVEIAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATTLTEAGYVGEDVENIVQKLLQKADYDVEKAQKGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKMIEGTVASIPPQGGRKHPQQEFIQIDTSNILFICGGAFAGLEKIVQQRQEKGGIGFTADVKNKDETKKLAELFRQVEPTDLVKFGLIPEFIGRLPVIATLEELDEEALMQILTEPKNALTRQYQYLFNMENVDLVFEDSALRAVAKRALERNTGARGLRSILENVLLETMYDLPSRTDVGTVFINEAVINGEAEPVYKSERQPKEAVTHESVAKADLKVIDSKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SUB3_TRIVC
Sequence: MGCIKVISVFLAAIAAVDARAFFHNRGGNDVIPNSYIVVMKDGVTAEDFDSHISSVAATHSLNKAKRGSETVGHKDSFNINGWRAYNGHFDEATIESILKDDKVNYVEHDRVVKLAALTTQPNAPTWGLGRVSHKAPGNKDFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNTVDNDNTDGNGHGTHTAGTFAGTTYGVAKKANIVAVKVLSAGGSGSTSGVIKGIDWCVTDARSKNALGKAALNLSLGGSFSQASNDAVTRAQEAGIFVAVAAGNDNRDAKNSSPASAPAVCTAASSTIDDQKSSFSNWGTIVDIYAPGSNILSAAPGGGTRTLSGTSMASPHVCGVGAAMLAQGVSVAQACDRLKQIGNAVIRNPGTGTTNRLLYNGSGR
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLYB_ASPTN
Sequence: MRLPTLFMLAAIATASPMSDLNRREMTRRQAAESCPIGYCTQNGGTTGGTAGDTVTVTDLAGLTEAAENETPLTIIVSGAISGSAKIRVASDKTIYGETGSSITGVGFYIRRVSNVIMRNLKIGQVDADNGDAIGIDESTNVWVDHCDLSGDLSAGKDDLDGLLDITHGAEWITVSNTYFHDHWKGSLIGHSDSNEGEDLGHLHITYANNYWYNVNSRTPSIRFGTVHIINNYWDNLLLTGVNCRMDAQVLVQSSAFSNCPDEAIFFADSDYTGYAVVDDVDLGGSTNSVPEGTLTPSSLPYDAIEAIGSAQIATTIPGTAGQKL
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase B.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYOE_PSYIN
Sequence: MANSITHNTATVSASLNEDSLTESRLPTINDYLELCKIKVVALLVLTALVGLALAPDMGRGYFVQLLSLFGIGLLSSSAAVINHIVDSKIDAKMVRTKNRPLVRKAVSRRQALIFSAVIGTLGFSLLVFAANWLTAQMTLFALVGYAFVYTMFLKRATPQNIVIGGLAGAMPPLLGWISETGQLAAQPWILVMIIFTWTPPHFWALAIHRKADYAKAKIPMLPVTHGTDFTKTCILLYSLLLTVVCFLPFLIHMSGYLYLFVAMLINIIFIYKAVALKLSETSYGALNLFKYSILHLTLLFIALFADKFLM
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYI_MYCBO
Sequence: MTDNAYPKLAGGAPDLPALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQIEAMGIAAFNDACRASVLRYTDEWQAYVTRQARWVDFDNDYKTLDLAYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVGFKVVGGQPDNGLDGAYLLVWTTTPWTLPSNLAVAVSPDITYVQVQAGDRRFVLAEARLAAYARELGEEPVVLGTYRGAELLGTRYLPPFAYFMDWPNAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIAPVTPVDSKGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIRHETYEHPYPHCWRCRNPLIYRSVSSWFVRVTDFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDELERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMPYAQVHYPFENLDWFQGHYPGDFIVEYIGQTRGWFYTLHVLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVTEVFDRDGSDAMRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPLWNTYSFLALYAPKVGTWRVDSVHVLDRYILAKLAVLRDDLSESMEVYDIPGACEHLRQFTEALTNWYVRRSRSRFWAEDADAIDTLHTVLEVTTRLAAPLLPLITEIIWRGLTRERSVHLTDWPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLPKLIVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGRFELTVNARVAGPRLGKDVQAAIKAVKAGDGVINPDGTLLAGPAVLTADEYNSRLVAADPESTAALPDGAGLVVLDGTVTAELEAEGWAKDRIRELQELRKSTGLDVSDRIRVVMSVPAEREDWARTHRDLIAGEILATDFEFADLADGVAIGDGVRVSIEKT
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_PSEMY
Sequence: MTEANRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQDRDVRVLADVLQTRMNFEMGVTDFMLGFAEQIRPAHVCLVPETRQELTTEGGLDVAGQEARIAAAVERLTLAGCEVSLFIDAEERQIEAAMRVGAPAIELHTGRYADAHTAEEAAQELSRIRDGVICGLNHGLIVNAGHGLHYHNAEAVAAIPGINELNIGHAIVAHALFVGFKQAVAEMKALIVAAAYRG
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK1_BACSU
Sequence: MKFAVSSKGDQVSDTLKSKIQAYLLDFDMELDENEPEIVISVGGDGTLLYAFHRYSDRLDKTAFVGVHTGHLGFYADWVPHEIEKLVLAIAKTPYHTVEYPLLEVIVTYHENEREERYLALNECTIKSIEGSLVADVEIKGQLFETFRGDGLCLSTPSGSTAYNKALGGAIIHPSIRAIQLAEMASINNRVFRTVGSPLLLPSHHDCMIKPRNEVDFQVTIDHLTLLHKDVKSIRCQVASEKVRFARFRPFPFWKRVQDSFIGKGE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.  It can use ATP and other nucleoside triphosphates (GTP, UTP) as well as inorganic polyphosphate (poly(P)) as a source of phosphorus.
What are the official names of this protein?
NAD kinase 1, ATP-dependent NAD kinase, Poly(P)-dependent NAD kinase, PPNK.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_STAAM
Sequence: MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVNEIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMVNTELDRMVSEFAQRIQQQGLDLQTYFQISGQDETQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PIMT_KLEP3
Sequence: MVSKRVESLLNQLRTQGIVDERVLEAIALVPREKFVDEAFEHKAWENTALPIGQGQTISQPYMVARMTELLTLTPESRVLEIGTGSGYQTAILAHLVHHVCSVERIKSLQWQARRRLKQLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALLAQLDDEGVLVLPVGEEHQFLKRIRRRGNEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2028_DICDI
Sequence: MNFIKKVIGGGSSKSKTDIKIEDEQHEQQHEQQHEKQQIPDKISTSKVNSPCVPPTCTYISKENVRSDLSLIKDFNSAYYYNYYRTLEKNSTNLLTSPGLNTKVVSNQFTLKEFNIVSEMTDSCIVSVWTQKYSNLSLTPVEAVYQIPLAPYATVSDFSVILKDKVLKGKIKENEKAKEKYNDAIASGGQAFLAEKVEGFFKLQIGNLPPQEDVTVNITITSEIGTHLESLHFCLHRFIFPKSAFKFNYTLNASLSTPIETIEMDHFQPTITYKDESKTNATVTISTENGVSNNIIAIIVPKYSEKPESFIEYSPIDKSYALAINFYPKFSVGLDEVDQKSEFIFVLDCSGSMSGKPIEKSKMALEICMRSLNENSKFNIVCFGSNFNKLFETSKHYNDETLQKASEYINRIDANLGGTELLEPIVDILSKESDPEFPRQVFILTDGEISNRDKLIDYVGKEANTTRIFTYGIGSYVDKELIVGVSKACKGYYEMIVDNSDMEEKVMKLISIAMQPTLSNIKVDWGVLSNVVQSPAQIRPLFNQERMMIYATLDKEPTEKQVTVILSGNGPLSERISFPVDLDFSKANQSTSHIHTLSAFKHIQDLEESERKEKKDNKDKIVKLGKRFGLVSKHTSYIVTADSDKVTEETMKTVQVLEPTQQINTSPGSGSGFIPTTRVQGSSSVFPSSPTPLSGPSPYTVCAPPPPPPTSSPYTNCAPPPPQFSRCIAPQPYQSAPAPPAPPAPSRLSQAQSQMDYCDQELLCESLEGDLLVEEEELECKEIECSPPQKLSYITPFAPTSQISQSSRECRSKKSSSPTIQKSSSLPSRPSTSSSSLIEIIRQQKANGSFTKSSVSSFINVDTPPPSSDIPEDVWTTLLIIANFILNFDSQKSQWELVSQKATKFVKQQIIKSSIASTFETLLESAKKSISN
What are the official names of this protein?
von Willebrand factor A domain-containing protein DDB_G0292028.
Protein: CYF_PHAVU
Sequence: MQTRNAFSCIKEGITRSISISVMIYIIIRAPFSNAYPIFAQQGYENPREATGRIVCANCHLANKPVDIEVPQAVLPDTVFEAVVRIPYDMQVKQVLANGKKGTLNVGAVLILPEGFELAPPDRISPEIKEKIGNLSFQNYRPTKKNILVVGPVPGQKYKEITFPILSPDPASKRDIHFLKYPIYVGGNRGRGQIYLDGSKSNNNVYNATAAGIVKKIIRKEKGGYEITIVDTLDEHEVIDIIPPGPELLVSEGESIKLDQPLTSNPNVGGFGQGDAEIVLQDPLRVQGLLFFLASIILAQIFLVLKKKQFEKVQLFEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: S35A5_MOUSE
Sequence: MKVIFLRQLKTRGMERKCSRRPGLGPPTLYTFLLGIIFITLSSSRILLVKYSANEENKYDYLPTTVNVCSELMKLILCILVSLCVIKKEDHQSRHLRCTSWKEFSSFMKWSIPAFLYFLDNLIVFYVLSYLQPAMAVIFSNFSIITTALLFRIVLKRHLNWIQWASLLILFLSIVALTASTKTSQHELAGHGFHHDAFFTPSNSCLHFRRDCSLRDNCTSKEWTFSEVQWNTTARVFSHIRLGLGHVLIIVQCFISSMANIYNEKILKEGTQLTESIFIQNSKLYFFGIVFNGLTLVLQSSNRDQIQNCGFFYGHNAFSVVLIFVTAFQGLSVAFILKFLDNMFHVLMAQVTTVIITTVSVLVFDFRPSLDFFLEAPSVLLSIFIYNASKPQNLECAPKQERIRHLSGSLWERSSGDGEELERLTKLKSDDSDDDTL
What are the official names of this protein?
Probable UDP-sugar transporter protein SLC35A5, Solute carrier family 35 member A5.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL18_PSEPK
Sequence: MTDKKVIRLRRARKARLKMHELEVVRLCVFRSSQHIYAQVISADGSKVLASASTLDKDLRDGATGNIDAATKVGKLVAERAKAAGVSQVAFDRSGFKYHGRVKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PK1_DELRA
Sequence: AGPSATTGVWFGPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
CAPA-Pyrokinin, CAPA-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_DICNV
Sequence: MRFVDEVVINVKAGKGGNGIVSFRREKYIEFGGPDGGDGGDGGSVYLRASDGLNTLSDFRYTRHFEAENGAAGEGRNKRGRSGEDLYIDVPLGTQVFVAETDELMGDLTAVGQTLLVAKGGFHGIGNTRYKSSVNRAPRQCKAGGLGEERVIRLELKLLADVGLLGMPNAGKSTLIAQVSSAKPKIADYPFTTLHPNLGVVRVGALQSFVMADIPGLIAGAADGMGLGHQFLRHLARNRILLHLLDCSPMSDSQNPITDFEQVSAELIKYDADFAQIPRWLVLNKMDTLPPELWQQKQEEIVRALNWQGKVFSISAAAGIGTAELCTAIMQELTAMKANQTAENDEPNAPELI
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_COXBN
Sequence: MSTQLRAAEISDIIESRIEKFGIKAEERTEGTILNIKDGIVRVYGLRDVMFGEMVEFPENTYGLAFNLERDSVGAVVMGPYEHLEEGMTARCTGRILEVPVGEALLGRVVDGLGKPIDGKGPIDTSETSPIEKVAPGVITRKSVDTSLPTGLKSIDAMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKHTGVKCIYVAIGQKQSSVAAVVRKLEEHGAMEHTIVVNASASEAAALQYLAPYAGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSRLLERAAHVNEAYVKEFTKGKVTGKTGSLTALPIIETQAGDVSAFIPTNVISITDGQIYLDVNLFNAGIRPAINAGLSVSRVGGAAQTKIIKKLIGGLRIALAQYRELEAFSQFASDLDEATRKQLEHGQRVMEILKQPQYQPLSVGEMAIIWYVVNNNYLDQVELKKVVDFERSLLSFLRDQHQDLLDEINKNPNYSEKIIEKIKAVVEEFVKTQSY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLCNK_MYCS2
Sequence: MIELDRLDLGGGRRLVITSEPDAAVPQVRDADGHWRRAGPGDGVAEAMLDALNQNPGTTKHGNFTLLSWASQTARGERPITVDQTNESVIVGDAAVVKWATHLQEGPHPAPARIKALRGNGFRGMPMPWGLVTWQTADHPETLVVTVDEYLPDAVDGWTWAVALVTDAAQDRAAVPALVDAVTAVGCVVAELHAAQADTARPATAADARSWREAALETVETAATLGTSVSGELLRARREDVEAVVGTLGDLAGIPVLAGHGDLHVGQVLRAGGRYVVTDFDGNPVLPAEARVKPVPAALDVAGMAQSLAHVAIVACKYTELAPAALADVDRLARTTFVGAYTDRLETLGHRSVYDPAPLRALRLQQVLREIIYAARHLPRWMYVPDAALPALLDEGTST
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of D-glucosamine (GlcN) to D-glucosamine 6-phosphate.  May be involved in the phosphorylation of acquired extracellular GlcN derived from the hydrolysis of chitosan, i. e. , in the incorporation of exogenous GlcN into the bacterial GlcNAc metabolism.  Is unable to phosphorylate maltose.
What are the official names of this protein?
Glucosamine kinase, GlcN kinase, GlcNK.
What is the protein family that this protein belongs to?
Belongs to the actinobacterial glucosamine kinase family.
Protein: STAM2_MOUSE
Sequence: MPLFTANPFEQDVEKATNEYNTTEDWSLIMDICDRVGSTPSGAKDCLKAIMKRVNHKVPHVALQALTLLGACVANCGKIFHLEVCSRDFATEVRSVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGVTFPSAGSQTVAAAAKNGTSLNKNKEDEDIAKAIELSLQEQKQQYTETKALYPPAESQLNNKAARRVRALYDFEAVEDNELTFKHGELITVLDDSDANWWQGENHRGTGLFPSNFVTTDLSTEVETATVDKLNVIDDDVEEIKKSEPEPVYIDEGKMDRALQILQSIDPKESKPDSQDLLDLEDVCQQMGPMIDEKLEEIDRKHSELSELNVKVLEALDLYNKLVNEAPVYSVYSKLHPAHYPPAAAGVPVQTYPVQSHGGNYLGHGIHQVSVAQNYNLGPDPMGSLRSLPPNMNSVTAHTVQPPYLSTGQDTVSNPSYMNQSSRLQAAAGTAAYTQPVGMSTDVSSFQNTASGLPQLAGFPVAVPAPVAAQPQASYHQQPLL
What is the function of this protein?
Involved in intracellular signal transduction mediated by cytokines and growth factors.  Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction.  May also play a role in T-cell development.  Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex).  The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).
What are the official names of this protein?
Signal transducing adapter molecule 2, STAM-2, Hrs-binding protein.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GPDA_CAUVC
Sequence: MTFEKVGVIGAGAWGTALAQVAARAGLAVTLQAREPEIVAAINDTHENAVFLPGIALEPGIKAVADLADLADCDLILAVAPAQHLRAALTAFAPHRKAGAPVVLCSKGVEQGSLKLMTDVAAEALPGAPIAVLSGPSFAGEVARNLPAAVTLACEDEALGRAIAEAIAIPTFRPYTANDLIGAEAGGAVKNVLAIACGIVEGKGLGRNAHATVITRGFAELTRLAVALGARPETVAGLCGLGDLVLTCSSPQSRNMSVGLALGQGLTLEQALAGKVSVAEGVASAPAVRALARKVGVEAPICEAVAAILAGEVAVDAAIAGLLSRPLKPEA
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_LACE2
Sequence: MAKAKFERTKPHCNIGTIGHVDHGKTTLTAAITKTLHERLGTGEAVAFENIDKAPEERERGITISTAHVEYETEKRHYAHVDCPGHADYVKNMITGAAQMDAGILVVAATDGVMAQTREHILLARQVGVPYIVVFMNKCDMVDDPELLELVDMEIRELLNEYGFPGDDTPIIQGSALKALEDPNSEWGDKILELMHTIDEYVPDPERDTDKPFLMPVEDVFSITGRGTVATGRVERGVLHVNEEVEIVGIHEDIRKVVVTGIEMFRKLLDEAQPGDNIGALLRGVQRDEIQRGQVLCKPGSITPHHKFTAQVYVLTKDEGGRHTPFFNNYRPQFYFRTTDVTGVCELPAGTEMCMPGDNVEMTVELIHNVAMEQGLRFAIREGGRTVGSGAVATIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAN2A_RUMFL
Sequence: MSEKNMEKAGVVKADELDEMIDETTGGASTVNTVGIHTTYLISKGLQNCPLKPTTILPILPRK
What is the function of this protein?
Lanthionine-containing peptide that does probably not show antibacterial activity, since its analog [+3]Flvbeta. a does not show antibacterial activity against M. luteus (PubMed:27028884).  Also does not show antibiotic activity when tested with [Del2]Flvalpha. a, an analog of Flvalpha. a, which is encoded by the same operon than Flvbeta. a (PubMed:27028884).  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores (By similarity).
What are the official names of this protein?
Lantipeptide Flvbeta.a.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_COXBN
Sequence: MKLIIGVITLFPQMFDALKSGVIGRALKQDRLTLSFWNPRDYATDPHRTVDDRPYGGGPGMVMKFEPLALALKAAKAQLGENTKVIHLTPQGKLLTQAIVREKIHASPLILLAGRYEGIDERLIEAEVDEEWSIGDYILSGGELPAMVLIDAMTRLLPGVLGHKDSASQDSFTAGLLDYPHYTRPEKIADRPVPSVLLSGDHEAISRWRLKQSLGRTWQRRQDLIKRRSLSENEQRLLDEFFEESS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.