PharMolix/UniProtQA huggingface dataset:
Protein: PYRD_SALAI
Sequence: MLFERVVRPTLFRLKGGDAEAAHEFAVRRLAGLARMPAALAVLRARYGVSAPRTVFGLRFPNPVGLAAGMDKDGLALPAWPALGFGFVEVGTVTAHPQPGNPRPRLFRLPDSGAVVNRMGFNNAGAGALAARLAALPRPLGVPLGISLGKSRITPLEEAVEDYQTSYRALREYGDYFAVNVSSPNTPGLRELQDRAHLDALLAALVGEKPILVKIAPDLPEPAIAELLEVCLARGVAGVIATNTTLARDGLAPADQAGGAEAGGLSGRPLADRAREVVAFVHRETDGRLPIVGVGGIVTPDDAGRMFDAGASLVQLYTGFVYRGPALVRAAAAAARTP
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SLYX_OLEA2
Sequence: MTKTLEDRIIKLEETVYFQEKTISELNDALTQQQLQLDEMHKLQQAVEIKLRQMAPLLRDADAGDDGPPPHYL
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: RBM5_XENTR
Sequence: MGSDKRVSRSERSGRYGSAFDRDDRDDRDTRSRRRDSEYKRYRDERSSERYDDYRDYDSPERDRMRDRERRNSDRSEDGYHSDGDYMDHDYRQDYYMDEKESKTIMLRGLPININENDIRELVESFEGPQPADVRLMKRKTGLSRGFAFVEFYHLQDATRWMEANQKKLVIQGKTIAMHYSNPRPKFEDWLCNKCGLYNFRRRLKCFRCGAAKAESDLEAPSGSSDAPQSTDYYSDSGYVSSAIILRNIGPHTVVDSILSALAPYVSLVVSNIRLIKDKQTQQNRGFAFVQLPSTLEASQLLQILQTLHPPLKIDGKTVGVDFAKSARKDLVLPDGHRVSAFSVASTAIAAAQWSSTQQAQQSGEGGEYAYLQPGQEGYANYGQCSQDYQPFYQAQTGAAEQSTAPQAEGSAPVPATTSAVVCQSPQMYQQPGSPTQSGTSTAANTTPASTTSTTEEAAPPNAVIPGVKYSVPDTSTYQYDESSGYYYDPQTGLYYDPNSQYYYNSLTQQYLYWDGEKQTYLPAADGAGQSGAQPNGANAGSSKEGKEKKEKPKSKTAQQIAKDMERWAKSLNKQKENFKNSFQPLSARDEERKESAAADAGFALFEKKQGALLERQFMPDMMMMVNTEEEEKPPNKALVAAYSGDSDNEEESERLLGAVDEEKLLDWKKLACLLCRRQFPNKDALTRHQQLSDLHKQNLEVYRRSKMSEQELEALELKEREAKYRDRAAERREKYGIPEPPEPKRKRFDPTVVNYEQPTKDGIDNSNIGNKMLQAMGWKEGSGLGRKSQGITAPIQAQVRMRGAGLGAKGSSYGVNTSDSYKDAVRKAMFARFSEME
What is the function of this protein?
Component of the spliceosome A complex.  Regulates alternative splicing of a number of mRNAs.  May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron (By similarity).
What are the official names of this protein?
RNA-binding protein 5, RNA-binding motif protein 5.
What is the protein family that this protein belongs to?
Belongs to the RBM5/RBM10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSM6_LACBS
Sequence: MDNSPPPPSNESPPPQPPPPQATHTGSPTDFLKGVVGKRVIVRLTSGVDYRGLLSCLDGYMNIALEQTEEHVNGVVTNRYGDAFIRGNNVLYISAAEPI
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates.  Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.  Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6. U5 tri-snRNP, and free U6 snRNP).  It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm6.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TTLL4_CAEBR
Sequence: MSSGYSSAPSVSHTSSEADLNRIESYEDGVDEEASDEQRMCGLSELVTSCLTSSKSSRQKDSFEDDDDVPIEIVGTLKKSKSKKKKQCPPNITIEKKNGNSSPFLKSSQFTDVPPTIRFYTKGTKVTKPARKIQSRLTWCHNSLLPIVMRQTLSASHFTIVDESLFHIGYWGRHLKSAQYKALQPHQKVNHFPGAFHIGRKDRLWMHIRNRLEHFGEEFEIMPFTYILPTDRQELLKYLETDVNRHVIIKPPASARGSGITVTRKPKDFPTTATLVAQHYIERPLTINRAKFDLRLYAYVPTFEPLRVYIYDQGLVRFASVPYNPSVTNISNKYMHLTNYSINKLAEADGIANKPVPKWALHQLWDYFDQMGVNSQKIQKEIEDVIVKAFISCEKPIREHMSRFLEQEFICYELFGIDIILDEDYKPWLLEVNISPSLHSGTSLDVSVKAPLAKDVLNLAGIHVPPSFDKLHTADYSCRPRNGTKTREQLVKEASWVAAYRDQHGAIDNRIFKRLTPEDTRALVEFEDELDRIGDFKLVFPTAQTAHYQKFFAEPIYMNILLQQWQIAQEGDRSIGIDRLEQLCRQKHMQSDQEISF
What is the function of this protein?
Monoglutamylase which modifies tubulin, adding a single glutamate on the gamma-carboxyl group of specific glutamate residues of target proteins.  Involved in the side-chain initiation step of the polyglutamylation reaction but not in the elongation step.  Preferentially modifies beta-tail tubulin over the alpha-tubulin.  Involved in side-chain glutamylation of tubulin in sensory cilia.  Together with ttll-5 and ttll-11, required for male mating.
What are the official names of this protein?
Tubulin polyglutamylase ttll-4, Tubulin--tyrosine ligase-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
Protein: RL332_BACCN
Sequence: MRVNITLACTECGDRNYITKKNKRNNPERIELKKYCPRLKRVTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: HUTI_PSE14
Sequence: MKTLWKHCHIASMAHGKYSIIENAAIVTSGALIEWIGPETELAEPEHDNCIDLGGAWVTPGLIDCHTHTVFGGNRSGEFEQRLQGVSYAEIAAAGGGIASTVRATRAASEDELYASAERRLRHLLKDGVTTVEMKSGYGLDLENERKILRVIRRLGNTQPVTVRATCLAAHALPPEYADRAADYINHICNDMLPALAAEGLVDAVDAFCEYLAFSPAQVEQVFISAGQLALPVKLHAEQLSSLGGSSLAAHYKALSADHLEFMTEDDAVAMAAAGTVAVLLPGAFYFLRETQLPPMEALRKHGVPIAISTDLNPGTSPGLSLRLMLNMACTLFRMTPEEALAGVTFNAAKALGMSATHGSLEVGKVADFVAWDIERPADLAYWLGGDLDKRIVRHGVESSI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_ASPFL
Sequence: WGATVITNLMSAIPWIGQDIVEFIWGGFSVNNATLNRFFALHFLLPFVLAALALMHLIAMHDTVGSGNPLGISGNYDRLPFAPYFIFKDLVTIFIFFIVLSIFVFFMPNALGDSENYVMANPMQTPPAIVPEWYLLPFYAILRSI
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HSP31_CANAL
Sequence: MVKVLLALTSYNETFYSDGKKTGVFVVEALHPFEVFRKKGYEIQLASETGTFGWDDHSVVPDFLNGEDKEIFDNVNSEFNVALKNLKKASDLDPNDYDIFFGSAGHGTLFDYPNAKDLQKIATTVYDKGGVVSAVCHGPAIFENLNDPKTGEPLIKGKKITGFTDIGEDILGVTDIMKKGNLLTIKQVAEKEGATYIEPEGPWDNFTVTDGRIVTGVNPQSAVKTAEDVIAAFECN
What is the function of this protein?
Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step.  Selective for MG, does not use glyoxal as substrate.  Plays a role in detoxifying endogenously produced MG, particularly when glycerol is the principal carbon source (PubMed:24302734).  Important for viability in stationary phase (By similarity).
What are the official names of this protein?
Glyoxalase 3, Glutathione-independent glyoxalase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HSP31-like subfamily.
Protein: NDHH_AETCO
Sequence: MNRPVTRKDLMIVNIGPHHPSMHGVLRLIVTLDGGDVVDCEPILGYLHRGMEKIAENRAIIQYLPYVTRWDYLATMFTEAITVNGPEQLGNIQVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFREREFVYDLFEAATGMRMMHNFFRIGGIAADLPYGWIDKCLDFCDYFLTEVVEYQKLITRNPIFLERVEGVGILGGEEAINWGLSGPMLRASGIQWDLRKVDRYECYDEFEWEIQWQKQGDSLARYLVRLSEMTESIKIIQQALEGLPGGPYENLERRGFDRKMNSEMNSEMNSEWNNFDYRFISKKPSPTFELSKQELYVRVEAPKGELGIFLIGDQSGFPWRWKIRPPGFINLQILPELVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: AROA_CHLL3
Sequence: MSVFKGEVTSLPPDKSISHRAALIASLSDGETEIMNFSAGFDNQSTLGVLQACGIPVRQEEVPGPWGTAILRVVIKSKGLWSLTPPSAPLQCNNSGSTMRMFSGILAGQPFQSELVGDASLLKRPMRRIADPLIQMGAGVSLSPIGTAPVVITGSKDLHAIDYRLPVASAQVKSLVAFAGLHAEGETRIYEPLSSRNHTELMLGLEPRVENEERVIVVPGRRQREARPFQIPADPSAACFIVSLGLLARGSEIMIRDVCLNPTRAAFLDILIRAGAAVTIENRRTVGGESIGDILVEGTRDMEPLVISDPQEVAIAIDELPMLGVLSAFATERFELMNAGELRTKESDRIEALALNLERLGFVCHQEPGGLSVTGRKGRPSGPVVVECFDDHRIAMSFAVASKACGEDIELSDREVAGVSFPNFFSLLDALEV
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_SHIDS
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: Y4096_PSEA7
Sequence: MKRICSVYKSPRKNEMYLYVDKREALSRVPEALLVPFGAPQHVFDLLLTPERQLAREDVAKVLENIEKQGFHLQMPPGEEEYIEHLPEELLRMNDPL
What are the official names of this protein?
YcgL domain-containing protein PSPA7_4096.
Protein: FENR_METS5
Sequence: MAEYEVIVIGGGPVGLFGTFYSGLRDMKVLLIDSQDELGGQLVTLYPEKMVYDVGGFAGIQAYDLAQRLIEQAKMFGPDIRTREWADTLEKTQDGMWVVKTDKGGEYKTKTVMIAAGIGKITPSRLGAKGEVEYENKGVYYTVRRKSEFQGKRVLIVGGGDSAVDWALTLAPIAKEVTLIHRRDQFRAHERSVKEMFEVAKVYTWHELKEVKGDGNRVTQAIIFDNRTKEEKTLNVDAVIISIGHKGDLGNMLKWGLNMKGRDIVVNGKMETNLPGVYAVGDIASVEGMPKLALIAVGFGQAAIASSVAKKYVDPNASVFAGHSSEMDKFKK
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: SMA9_CAEEL
Sequence: 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
What is the function of this protein?
Transcription factor, probably acting as a transcriptional activator (PubMed:17397820).  Required for patterning of male-specific genital sensilla (simple sense organs), known as rays (PubMed:20565799).  Dispensable for regulation of body size (PubMed:20565799).
What are the official names of this protein?
Transcription factor sma-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPIS_CLOB1
Sequence: MRTAIIAGNWKMNKTVKEAVELVKELKPLVKDAKCDVVVCPTYVCLPAVLEEVKGSNIKVGAQNMHFEESGAYTGEIAPKMLEELGVHYVIIGHSERRQYFNETDETVNKKVKKAFEHNLIPIVCCGESLEEREGNITEKVLEGQIKVGLKELSKEQVEKLVIAYEPIWAIGTGKTATDEQANETIGYIRTVVKAMYGESVADKIRIQYGGSVKPGTIKAQMAKEEIDGALVGGASLKAEDFAAIVNY
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_STRP2
Sequence: MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFGGMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLKEVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVLPIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKENESVIIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_SHESH
Sequence: MALIEPTAINNKKVIVGMSGGVDSSVSAYLLLKQGYQVEGLFMKNWEEDDTDEYCAAADDLKDAQAVCDKLGIKLHTVNFASEYWDNVFEYFLAEYKAGRTPNPDIICNKEIKFKAFLEFADDILDADYIAMGHYVRRSDESGQSQMLRGRDGNKDQSYFLYTLSHEQISRSLFPVGELEKSEVREIAKEMGLVTHDKKDSTGICFIGERKFTDFLSTFLPAQPGNIETAEGEIIGKHQGLMYHTLGQRKGLGIGGMKNSNDDPWYVVDKEMDRNVLVVGQGGHHPRLMSVGFYADQLHWVDRKGPIDGAQITVKTRYRQRDVACTLTYEGDDRIKVIFDEPVAAVTPGQSAVFYDAELCLGGGIIDSLIRE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSD_CITK8
Sequence: MRFAIVVTGPAYGTQQASSALQFAHALVNEGHELSSVFFYREGVYNANQLTSPASDEFDLVRAWQQLGAQHGVALNICVAAALRRGIVDETEAKRLALASANLQPGFSLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSTD2_HUMAN
Sequence: MPSSTSPDQGDDLENCILRFSDLDLKDMSLINPSSSLKAELDGSTKKKYSFAKKKAFALFVKTKEVPTKRSFECKEKLWKCCRQLFTDQTSIHRHVATQHADEIYHQTASILKQLAVTLSTSKSLSSADEKNPLKECLPHSHDVSAWLPDISCFNPDELISGQGSEEGEVLLYYCYHDLEDPQWICAWQTALCQHLHLTGKIRIAAEGINGTVGGSKLATRLYVEVMLSFPLFKDDLCKDDFKTSKGGAHCFPELRVGVFEEIVPMGISPKKISYKKPGIHLSPGEFHKEVEKFLSQANQEQSDTILLDCRNFYESKIGRFQGCLAPDIRKFSYFPSYVDKNLELFREKRVLMYCTGGIRCERGSAYLKAKGVCKEVFQLKGGIHKYLEEFPDGFYKGKLFVFDERYALSYNSDVVSECSYCGARWDQYKLCSTPQCRQLVLTCPACQGQGFTACCVTCQDKGSRKVSGPMQDSFKEECECTARRPRIPRELLQHVRQPVSPEPGPDADEDGPVLM
What are the official names of this protein?
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2, Rhodanese domain-containing protein 2.
Protein: FLP03_CAEEL
Sequence: MISPNHLILLFCVNCAFLVASDATPKRSPLGTMRFGKRAIADEMTFEEDGYYPSNVMWKRSTVDSSEPVIRDQRTPLGTMRFGKRSAEPFGTMRFGKRNPENDTPFGTMRFGKRASEDALFGTMRFGKREDGNAPFGTMKFGKREAEEPLGTMRFGKRSADDSAPFGTMRFGKRNPLGTMRFGK
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.  SAEPFGTMRF-amide inhibits the activity of dissected pharyngeal myogenic muscle system.
What are the official names of this protein?
FMRFamide-like neuropeptides 3.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: G4P_BPF1
Sequence: MKLLNVINFVFLMFVSSSSFAQVIEMNNSSLRDFVTWYSKQTGESVIVSPDVKGTVTVYSSDVKPENLRDFFISVLRANNFDMVGSIPSIIQKYNPNNQDYIDELPSSDNQEYDDNSAPSGGFFVPQNDNVTQTFKINNVRAKDLIRVVELFVKSNTSKSSNVLSVDGSNLLVVSAPKDILDNLPQFLSTVDLPTDQILIEGLIFEVQQGDALDFSFAAGSQRGTVAGGVNTDRLTSVLSSAGGSFGIFNGDVLGLSVRALKTNSHSKILSVPRILTLSGQKGSISVGQNVPFITGRVTGESANVNNPFQTVERQNVGISMSVFPVAMAGGNIVLDITSKADSLSSSTQASDVITNQRSIATTVNLRDGQTLLLGGLTDYKNTSQDSGVPFLSKIPLIGLLFSSRSDSNEESTLYVLVKATIVRAL
What is the function of this protein?
Acts in the assembly and extrusion of the bacteriophage by forming a channel across the host outer membrane.  This channel is just large enough to allow a newly synthesized phage particle to pass through.  Extrusion is a process of concomitant assembly and secretion and takes place at specific assembly sites where host inner and outer membranes are in close contacts.
What are the official names of this protein?
Virion export protein, Gene 4 protein, G4P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G4P protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: ISPH_PETMO
Sequence: MEINVAKRTGFCSGVQKTYNEVKNSLVDKNKIYIYGELVHNRKVIEELNSAGAITITGMDDIPDDSIDETLIIRAHGISKAEKDLLKKRFSKVIDMTCPIVTNLVKYVEKKQKDGFFVVVYGKPDHPEILGLKGNVDESKLLITLSPVTIPQKKVLIVSQTTMGEEEYKNFITSILTINSFTEVLIRDTICSETILREKETLELSQKSTLMLVLGGKNSSNTQKLYRISKKYCKRTYHIESGEELKEITISPQDKIGIVTGSSTPTSELNKVLEYLSQEKEDFS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: KCY_GEOSW
Sequence: MRNNIRIAIDGPAAAGKSTVAKIIAKRLSYLYIDTGAMYRALTYVALQQKVALDDEQALISLLKNTYIELKSSEQGQLVFVNGEDVTNIIRSEEVTNAVSLVAKHPSVREEMVARQRALAKNGGVVMDGRDIGTYVLPNAEVKIFLKASVEERAKRRHAENIARGFPSDLETLKKEIARRDQIDSEREVAPLKKAEDAIEIDTTSLSIEEVVDRIMEIVNERIG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_ECO24
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSWSGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVSTGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIIEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNNL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: COX17_DICDI
Sequence: MSIAETNTTTEVAAPKKKMCCACPETKKVRDECIVANGEEKCAALIELHKVCLRKEGFDV
What is the function of this protein?
Copper chaperone for cytochrome c oxidase (COX).  Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity).
What are the official names of this protein?
Cytochrome c oxidase copper chaperone.
What is the protein family that this protein belongs to?
Belongs to the COX17 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: SSRP_UREP2
Sequence: MIVSNKHARRNYELLDFFECGIVLKGTEVKSISRANCSINEAYVQIIKNQALILNMHVANFFEGNNFNQDPYRNRKLLLHKKEIIRLQHLVKTQHMTIVPTKIYWKNNKLKIEIALGKGKQLHDKREDIKKRDLARETRLF
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.