PharMolix/UniProtQA huggingface dataset:
Protein: AGUA_SHESA
Sequence: MTNANVDATQLTTKPSEDGFYMPAEWAAQQAVWMIWPYRPDNWRSAGAYAQATFAKVADAIGGATPVYMGVPQAFLAEAQTVMPSHVTLVEIDSNDCWARDTGPTVVVNAEGECRGVDWGFNAWGGHNGGLYFPWDKDEQVAAQMLKQHGFARYSAPLILEGGSIHVDGEGTCMTTAECLLNANRNPDLTKEQIEALLRDYLNVKQFIWLEEGVYMDETDGHIDNMCCFARPGEVILHWTDDETDPQYPRSKAALDVLQNTVDAQGRKLKIHLLPQPGPLYCTEEESKGVTEGTGVPRTAGERLAGSYVNFLITNDRIVFPLLDPATDDIAAQKLQEIFPEHKIVGVPAREILLGGGNIHCITQQIPSGK
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: RECA_SHESR
Sequence: MKVDPNKEKALAAVLSQIEKQFGKGSIMKLGEDRSMDVETISTGSLSLDVALGAGGLPMGRIVEIYGPESSGKTTLTLEVIAAAQREGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIIVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGDEVVGNETRVKVVKNKVAAPFKQAEFQILYGQGINRTGELVDLGVAHKLIEKAGAWYSYKGDKIGQGRANAGKYLTENPAIAAEIDKTLRELLLSNPAALSSSASDDENSEGNVDFETGEVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAP4B_MOUSE
Sequence: MKMVAPWTRFYSHSCCLCCHVRTGTILLGVWYLIINAVVLLILLSALADPNQYHFSGSELGGEFEFMDDANMCIAIAISLLMILICAMATYGAYKQHAAWIIPFFCYQIFDFALNTLVAITVLVYPNSIQEYIRQLPPSFPYRDDIMSVNPTCLVLIILLFIGILLTLKGYLISCVWSCYRYINGRNSSDVLVYVTSNDTTVLLPPYDDATAVPSTAKEPPPPYVSA
What is the function of this protein?
Required for optimal lysosomal function.  Blocks EGF-stimulated EGFR intraluminal sorting and degradation.  Conversely by binding with the phosphatidylinositol 4,5-bisphosphate, regulates its PIP5K1C interaction, inhibits HGS ubiquitination and relieves LAPTM4B inhibition of EGFR degradation.  Recruits SLC3A2 and SLC7A5 (the Leu transporter) to the lysosome, promoting entry of leucine and other essential amino acid (EAA) into the lysosome, stimulating activation of proton-transporting vacuolar (V)-ATPase protein pump (V-ATPase) and hence mTORC1 activation.  Plays a role as negative regulator of TGFB1 production in regulatory T cells.  Binds ceramide and facilitates its exit from late endosome in order to control cell death pathways.
What are the official names of this protein?
Lysosomal-associated transmembrane protein 4B.
What is the protein family that this protein belongs to?
Belongs to the LAPTM4/LAPTM5 transporter family.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein. Late endosome membrane. Cell membrane. Cell projection. Lysosome membrane. Endosome membrane. Endosome, multivesicular body membrane. Endosome, multivesicular body lumen.
Protein: CH10_HAEIG
Sequence: MNIRPLHDRVIIKREEVETRSAGGIVLTGSAATKSTRAKVLAVGKGRILENGTVQPLDVKVGDTVIFNDGYGVKNEKIDGEEVLIISENDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN208_HUMAN
Sequence: MGSLTFRDVAIEFSLEEWQCLDTAQQNLYRNVMLENYRNLVFLGIAAFKPDLIIFLEEGKESWNMKRHEMVEESPVICSHFAQDLWPEQGIEDSFQKVILRRYEKCGHENLHLKIGYTNVDECKVHKEGYNKLNQSLTTTQSKVFQRGKYANVFHKCSNSNRHKIRHTGKKHLQCKEYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGEKPNKCEECGKAFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKGFSMFSILTKHKVIHNGEKPYKCEECDKATHAGEKPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKTFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYKSSSTLSYHKKIHTEEKPYKYEECGKGFSTFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSSLTEHKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGEKPYKCEECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSVFSKHKKIHTGEKL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 208, Zinc finger protein 91-like.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_YERPY
Sequence: MLDPNMLRNELDAVAEKLARRGFKLDVEVLRQQEERRKVLQVETESLQAERNSRSKQIGAAKARGEDIEPLRLEVNALGEKLDAAKAELDKLQNEIRDLALSIPNLPDDSVPVGKNENDNIEVSRWGEPRKYDFDVKDHVSLGEMAGGLDFAAAVKLTGARFVVMKGQIARMHRALSQFMLDLHTEKHGYLEAYVPYLVNHATLYGTGQLPKFGEDLFHTKPLAEESDNSNYALIPTAEVPLTNLVRDEILEEDSLPLKLTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQITRPEDSMAALEELTGHAEKVLQLLELPYRKVLLCTGDMGFGSSKTYDLEVWLPAQDTYREISSCSNMWDFQARRMQARYRNKTDRKTRLVHTLNGSGLAVGRTLVAVLENYQQADGRIQVPDVLRPYMGGLEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_ECOLU
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: Y1239_STAAW
Sequence: MQIELTDAAVTWFKNELELPENNKVLVFFVRYGGEFQLKQGFSPAFTVEPKEDVDIGYEQQYDDLNVVVAEKDLWYFEDDHIIVNVVDHEDEISYSTK
What are the official names of this protein?
Uncharacterized protein MW1239.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CH602_ROSS1
Sequence: MPKQLYFNEDARRALKRGVDIVADAVKTTLGPRGRNVSIDKKFGAPTVTHDGVTVAKEIELKDPFENMGARLLVEVATKTNDVVGDGTTTATVLAQSIVNEGLKMVAAGANPMLIKRGLDKAVEAVVAELKSVAIPVRDRADIAHVAAISAADSEIGDLIAEVMEKVGKDGVITVEESKGIAFEKEYTEGMQIDRGYISPYFVTNPERMEAELEDPYILITDKKISSIQDILPVLEKALQVTKNLVIIAEDVDGEALATLVVNKLRGTINALAVKAPGFGDRRKAMLQDIAILTGGTLISEEIGRKLDSATVEDLGRARRVVSDKDNTTIIEGRGDERAIRARIEQIRAQIETTTSDFDREKLQERLAKLAGGVAVLKVGAATEPELKEKKHRVEDALSTARSAVEEGIVPGGGVALLNAIPALDRVQVTYEDEKYGVQILRRALEEPMRQLARNAGEDGAVIIDTVRRLQKEKNDKNIGYNVLTGEFGSMIEMGIIDPVKVTRSAVQNAVSIAGLLLTTEALIADIPEEKPATPTPGGGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS34_ENCCU
Sequence: MEEWDGDVFTWNAGKEDIYTLIESILRLLKNGCKGMENMVVKYLGTGATDSLYMYFPWLRGRDLESRLSVEHQIDRFWKIRFELHEERTNSMDRYEDIVSSFLALDTKCGILGKLEGQMALVDEIRRIYSITSQGSPRKKRLREYRLHGTLCLHPGAGSMRLYASLFSLDATVKEIIFPEIEIFPSSTFPILVPLRTDRGVSRIIYKKGDDLTRDLFVLETIRYMSRLMGVDLVTYKVIPLSRKEGIVEVVDGIDFTRIRSRKDLEMYIEEDRDPRHQESFEKRKVFVSTLCGYSVACYVMGIGDRNPGNMMVTRDGKFFHIDFSHVFGRDPKPISSRITIARPIRDYLVNDELIYQDFLARSGEAFLQIRRSCRKIFVLWCILAQNRIFQFDLNEIIPFAQARLRMEMSEQRALELFEKEIRGAVGSLKTSVAHLINRVGMFLRR
What is the function of this protein?
Phosphatidylinositol 3-kinase required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I.  Also involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II (By similarity).
What are the official names of this protein?
Probable phosphatidylinositol 3-kinase VPS34 homolog, PI3-kinase VPS34, PI3K VPS34, PtdIns-3-kinase VPS34.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: YPF12_PLAF7
Sequence: 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
What are the official names of this protein?
Uncharacterized protein MAL13P1.304.
Protein: SMR3A_MOUSE
Sequence: MKPLNLVLGLCILVGCFLSCECHRGPRRHDPRGPFPPPPPPHGPGIGRPHPPPFGPGIGRPPPPPFGPGIGRPPPPPPCPPVPPHPRPPSNPSPPPTPSIPPTGPPTTVQATTMPAASISITTPTARDSTDIFWRLWELINSLLQQE
What is the function of this protein?
May play a role in protection or detoxification.
What are the official names of this protein?
Submaxillary gland androgen-regulated protein 3A, Salivary protein MSG1, Submaxillary gland androgen-regulated protein 1.
What is the protein family that this protein belongs to?
Belongs to the PROL1/PROL3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: COXZ_RHIE6
Sequence: MSDKAAAPKKQGRNNGAVVLMCLSFVFGMGAMSYAAVPLYRIFCQVTGYNGTTQRVEQMSSVVLDRKMRVTFDANVAPGLQWDFKPVEREVNPRIGETIQVKFTAENRSNETQRGQAVFNVTPGEAGVYFNKVQCFCFTETDLKPGEKLEMPVVFYIDPEIVNAVESKDIHTVTLSYTFYPKEGPKPLASNEGGAEKVEKKL
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein CtaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: Y4213_ARATH
Sequence: MAPIFRSTSLIAFSLFFFFFASTLPISSGSEDSYTITGRVRVPASTVIGHAAKFSNIKVILNGGQHVTFLRPDGYFTFHKVPAGTHLIEVYALGYFFSPVRVDVSARHRGKVQATLTETRRSLTELVLEPLRAEQYYEMREPFSVMSIVKSPMGLMVGFMVVVVFLMPKLMENIDPEEMKSAQEQMRSQGVPSLTSLLPASR
What are the official names of this protein?
ER membrane protein complex subunit 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the EMC7 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DGTP_CROS8
Sequence: MEKIDFRNKINWHRRYRSPQGVKSEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSLEVQQVGRYIAKEVLSRLKEQGLLEAYGLSELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFSQRLFPADAENLPVSQDRCTVQTLRLQEGEEALNALRGNVRRDLCHFEGNAQGIRLVHTLLRMNLTWAQVGGILKYSRPAWHHGPVPETHSYLMKKPGFYLSEDQYISRLRKELQLDTYSRFPLAWIMEAADDISYCVADLEDAVEKRIFSVEQLYQHLYDAWGEHAPGDLFNLVVQNAWDKSGTNQLHHSAEDQFFMYLRVNTLNRLAPYAAQRFIDNLPDVFNGSFNHALLEDDSPYSRLLELYKNVAVRHVFNHPDVEQLELQGYRVISGLLDIYSPLLALTLAQFRELVEKESVRSLPIESRLYHKLSSRHRLAYIEAVSHLHPQAADFPVWEYYYRCRLIQDYISGMTDLYAWDEYRKLMAVE
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: IF2_LEPIN
Sequence: MEDKNKTIKETLQGSADAGKRKKLIIKKKGDDPSTPSPAASPKKETVAESAPSSKPPVMPLPLPGDSGQSPIVRPAPSSHSPAKREESPGKQDAGRPPRDKDTRQGGGSSYPPSRSPFQKEDSNIIVSRPIQRTGPSRPNSGGGYQGNRGPGQGGGGYQGNRGPGQGGGGYQGNRGPGPGQGGGGYQGNRGPGQGGGGYQGNRGPRSGGTGTRPMPITSAEVELSQSRGSSVTSKKKGHDKEKSTSDRDFSGAENTKFFKQKFKKTKVVGVSGVSVPKEITLLENVQVGELAKKMNLKPGDVIGKLMKMGMMVTINNIIDAETAALLADEYGCKVKVVSLYEETIIEEEKDNQEDYINRPPVVTIMGHVDHGKTKLLDTIRRSSVIDTESGGITQHIGAYQVRTARGLITFLDTPGHEAFTSMRARGAKVTDIVVLVVAADDGVMPQTLEAISHAKAAEVPILVAINKIDLPAANPEKIMQELANHGLQSEEWGGETMYAKISARENIGIDKLLEMILLQAEVMDLKANPKRRAKGTIIEAKLDPGRGSVATVLIQNGTLRVGDPFVAGVFSGRVRAMYNDLGQLIQEAGPAFPAQVTGIDGVPDAGAPFDAMADEKEARNISQHRIEFERIGNAGAATGTSSKVTLENMNEFIKQGALKELKVIIKADVRGSAEAIKESLEKLSTPEVKLNVIQSGAGAIVDMDVMLASASNALIIGFHVRANPKTIALAEKEGVQIKYYNIIYQVVDEIKLAMEGLLEPEKIEEVIGTAEIREIFKVSKIGNIAGCMVLSGKIQKSANIRVIGDGVTKFEGKLKSLKRVKDDVNDVVAGFECGIQVDGYNDFKVGDTIEAYNVTVIKRKLE
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_ECO7I
Sequence: MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: C56D1_HUMAN
Sequence: MQPLEVGLVPAPAGEPRLTRWLRRGSGILAHLVALGFTIFLTALSRPGTSLFSWHPVFMALAFCLCMAEAILLFSPEHSLFFFCSRKARIRLHWAGQTLAILCAALGLGFIISSRTRSELPHLVSWHSWVGALTLLATAVQALCGLCLLCPRAARVSRVARLKLYHLTCGLVVYLMATVTVLLGMYSVWFQAQIKGAAWYLCLALPVYPALVIMHQISRSYLPRKKMEM
What is the function of this protein?
Probable transmembrane reductase that may use ascorbate as an electron donor and transfer electrons across membranes to reduce monodehydro-L-ascorbate radical and iron cations Fe(3+) in another cellular compartment.
What are the official names of this protein?
Probable transmembrane reductase CYB561D1, Cytochrome b561 domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AN_NPVAC
Sequence: MFASLTSEQKLLLKKYKFNNYVKTIELSQAQLAHWRSNKDIQPKPLDRAEILRVEKATRGQSKNELWTLLRLDRNTASASSNSSGNMLQRPALLFGNAQESHVKETNGIMLDHMREIIESKIMSAVVETVLDCGMFFSPLGLHAASPDAYFSLADGTWIPVEIKCPYNYRDTTVEQMRVELGNGNRKYRVKHTALLVNKKGTPQFEMVKTDAHYKQMQRQMYVMNAPMGFYVVKFKQNLVVVSVPRDETFCNKELSTENNAYVAFAVENSNCARYQCADKRRLSFKTHSCNHNYSGQEIDAMVDRGIYLDYGHLKCAYCDFSSDSRETCDSVLKREHTNCKSFNLKHKNFDNPTYFDYVKRLQSLLKSHHFRNDAKTLAYFGYYLTHTGTLKTFCCGSQNSSPTKHDHLNDCVYYLEIK
What is the function of this protein?
May play a role in maturation and encapsidation of viral replicated genome, by promoting DNA homologous recombination.  Exhibits endonuclease and 5'->3' exonuclease activities.  The endonuclease activity displays a specificity for ssDNA in vitro.
What are the official names of this protein?
Alkaline nuclease, AN.
What is the protein family that this protein belongs to?
Belongs to the baculo-herpesviridae alkaline nuclease family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: ITPA_CIOIN
Sequence: MASRKTISFVTGNKNKLKEVQQFLHGSSSINITSVPLDLPEYQGEPDDVSKQKCAEASKQLSGPVLIEDTCLCFNAMGGLPGPYVKWFLEKLGPEGIYKMLDGWEDKSGYALCTFAYSNGLQGDDVLLFRGKCEGTIVPPRGPRTFGWDPCFQPNGFNETYAEMSSELKNSISHRGKALEALSEYFKEKNCD
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C42S1_CHICK
Sequence: MSDFWHKLGCCVVEKPQPKKRRRRIDRSMIGEPMNFVHLTHIGSGDMAAGEGLPMTGAVQEMRSKGGRERQWSSSRVL
What is the function of this protein?
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly.
What are the official names of this protein?
CDC42 small effector protein 1.
What is the protein family that this protein belongs to?
Belongs to the CDC42SE/SPEC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor.
Protein: SMN_PONAB
Sequence: MAMSSGGSGSGVPEQEDAVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKSKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP.  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate.  Binding of snRNA inside 5Sm ultimately triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP.  Within the SMN complex, SMN1 acts as a structural backbone and together with GEMIN2 it gathers the Sm complex subunits.  Ensures the correct splicing of U12 intron-containing genes that may be important for normal motor and proprioceptive neurons development.  Also required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination.  May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).
What are the official names of this protein?
Survival motor neuron protein.
What is the protein family that this protein belongs to?
Belongs to the SMN family.
What are the subcellular locations of this protein?
Nucleus, gem. Nucleus, Cajal body. Cytoplasm. Cytoplasmic granule. Perikaryon. Cell projection, neuron projection. Cell projection, axon. Cytoplasm, myofibril, sarcomere, Z line. Note=Colocalizes with actin and at the Z-line of skeletal muscle (By similarity). Under stress conditions colocalizes with RPP20/POP7 in punctuated cytoplasmic granules. Colocalized and redistributed with ZPR1 from the cytoplasm to nuclear gems (Gemini of coiled bodies) and Cajal bodies. Colocalizes with FMR1 in cytoplasmic granules in the soma and neurite cell processes (By similarity).
Protein: RS6_UREPA
Sequence: MAKYEIMLVVRGDLDQEQANKVANELKATLKNTEVKENNYDGVQQLAYEINKLKTAYRYVYNFETTDVSLINEFRRLAIINKNVLRHIIINLEKDYGYKATVNTKKVQRNEKRAEVYARQKEEAERRAVERQAAYEAMKAEREAAGLPVKEFVKNTNSKR
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ASNA_STRA1
Sequence: MKKSFIHQQQEISFVKNTFTQYLIDKLEIVEVQGPILSQVGDGMQDNLSGIEHPVSVKVLNIPEAEFEVVHSLAKWKRHTLARFGFNEGEGLFVHMKALRPDEDSLDPTHSVYVDQWDWEKVIPDGRRNLDYLKETVEKIYKAIRLTELAVEARFDIESILPKRITFIHTEELVEKYPDLSPKERENAIAKEYGAVFLIGIGGELADGKPHDGRAPDYDDWTTPSENGFKGLNGDILVWNEQLGTAFELSSMGIRVDEDALKRQVVLTGDEDRLEFEWHKTLLRGFFPLTIGGGIGQSRLAMFLLRKKHIGEVQSSVWPKEVRDTFENIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJFY_SHIFL
Sequence: MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDVQSLGVIYINHNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR
What are the official names of this protein?
Uncharacterized protein YjfY.
What is the protein family that this protein belongs to?
Belongs to the BhsA/McbA family.
What are the subcellular locations of this protein?
Periplasm.