PharMolix/UniProtQA huggingface dataset:
Protein: RSBW_BACVZ
Sequence: MSTSVDYIEMKIPAEPEYVGIVRLTLSGVASRMGYTYDDIEDLKIAVSEACTNAVQHAYNDENKGEVSVRFGVFEDRLEVIVADQGDSFDFDQKQQDLGPYTPSHTVDQLSEGGLGLYLMETLMDEVKVQSNSGVTVAMTKYLNGERVDHGTTIKNYETN
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: RUVC_RHIME
Sequence: MQNTIRIIGIDPGLRRTGWGVIETLGNSLRFVASGTVTSDGELDLASRLCQLHDGLAEVVHGYQPHEAAVEQTFVNKDATATLKLGQARGIAMLVPARAGLRVAEYAPNAVKKAVIGVGHGEKQQIHMMLKVLMPKAEFKGNDAADALAIAICHAHNRQAVTSRLAALAG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ARNA_AERS4
Sequence: MKAVVFAYHDIGCTGIEALLEAGYEIQAVFTHADDPSENRFFGSVAQLCAEHGLPVYSPEDVNHPLWVEHIKGLAPQALFSFYYRHMLKQEILDIPSAGAFNLHGSLLPAYRGRAPINWCLVNGEQLTGITLHQMTMRPDAGAIVAQQAVAIKWADTALTLHGKVRLAAKALLDAELPKLRTGDISLTPQDESRASYYGRRTPADGELHWDKSARDLYNLVRAVTQPYPGAFSFAGDRKLTVWKATHIAQDSDMLPGTILSQDPLRIACGEGVLEIVAGQAEGGLYVRGAQLARELGLVAGMRLGAKASSALRKERLTRVLILGVNGFIGNHLTERLLKDGRYEIYGLDISASALGRFIDHPHFHFVEGDISIHTEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRYCVKYNKRIIFPSTSEVYGMCDDHSFDEDESRLIVGPIHKQRWIYSVSKQLLDRVIWAYGKKEGLNFTLFRPFNWMGPRLDSLDSARIGSSRAITQLILNLVDGTPIQLVDGGAQKRCFTDIEDGIEALFRIIENKGNRCDGQIINIGSPDNEASILQMAEVLLGKFEAHPLRHHFPPFAGFKRVESKSFYGDGYQDVSHRRPSIKNARRLLDWEPTIEMEETIGKTLDFFLQGAVSTGVEHD
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: TRMB_EDWI9
Sequence: MNDVITAEFDENGRAIRRIRSFVRRQGRLTKGQQLALDEYWPLMGVEFTPEALDLPTLFGREAPVVLEIGFGMGASLVAMAQQHPERDFLGIEVHSPGVGACLSSAHEAGVNNLRVMCHDAVEVLERMIPDASLDMVQLFFPDPWHKARHHKRRIVQSAFAGRIRGKLKISGVFHMATDWENYAEHMLEVMNHAPGYRNLSDDNTYVPRPDSRPVTKFELRGQRLGHGNWDLMFERVE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: HUTG_STRP1
Sequence: MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFEGTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPNRSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDAHFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGIQFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPNLAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHS
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: MCMBP_DICDI
Sequence: MTDNNNLDSLIIDKDEYLNSPMNVVDKLFKFDQNNLNNGTVYKKFENVISEDQIYKSIPLVSTINQCDLNSGKLVKIRCMIQDIFDPQFCPSFNKIKNIETNEIRLEASKYKDKINLNDCEELIFDSFDSSTFDKTILYCIPIPCENKWVNNNNNNNNNNNNNNNNNNNNNNNNGNEQISSSLLNKKKRNIDDADMKNENDEENKKSKDQKSTTTTTTTTSKEGEEEGEEGEQLTKSKKLLTNNKIDINKIFNYPIPIDSNDENNLKTPFIVNIYDDDIIFDENNKAVTFKINEIIEFVGVVAKFNPTLQHQSSNSSDQGETTTTIIDLMSMLDVDEISTIPDTLIPQFHAITYRYLDPYKFNHLNPFSIDTNTTINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNPNNNNPNNNNLNNNLIRNELIKFIKLFIVDELLSEYLLFHLISKVYSFTSGLSIGNFSMNISIPNDKEFQRLPQLIELLYEILLARSYRFSMSLENLNDMDVVPYKDYDRNRIVSGLLQLPKGTNLILDETQLTEGKVESQGIKVLNALNTLSIQQKVEYDFKYHPIEIQTDLPTISISFGKSLIKGTTQISINKSIQLPTINEINQQLIHSYNNDKLNQFRNYINHCKNLSFKISSPTTTTIAESDDATRHIQEDFVKSRQLDSKMTTDVFHYWLTLSRLVALSFNDQYIKIDKWNIMKSLEEKRKLTINNL
What is the function of this protein?
Associated component of the MCM complex that acts as a regulator of DNA replication.  Binds to the MCM complex during late S phase and may act by promoting the disassembly of the MCM complex from chromatin (By similarity).
What are the official names of this protein?
Mini-chromosome maintenance complex-binding protein, MCM-BP, MCM-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MCMBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCNA_METMJ
Sequence: MLKATIDAEIFRESIDAIAALVTECRLHTAEDQIRTRSVDTANVAMVSLELQSTAFNSFSATAGELGLDIAKMKNIIGMMGKGDALTLTLLDEERKLELSFGGYRYSISLLDVNTIRKDPNPPGIDLPGKAVVPGDALNNAIKAAAVISDKIALGIDPDAMTFYMEAEGDTDHIKLALGEDELVALSPVQARSLFSIDYLKDMGRVMARADKVEVYLGIDHPVRFVFDIADGNGRVEYLLAPRIEAD
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: YC13_KLEPN
Sequence: MIFNKVIERISILKNRCRSSECSIIGVLFRMLMFRLVYKKNILTSPKVKIKNIKNIKFNKNSNLIVGLSNVNHVNNNSICYINNRGEMHVSGNVFIAKSVRVDIADSSKIILNDCYIGPETDLISYSGISIGKGSMVSWRVQFLDEDFHLVSYNDKKPKDGKITIGENCLIGNNVAINKGCIIADGCVVASHSVVNGVFLEKNCLIAGVPARVIKRNISWQH
What are the official names of this protein?
Uncharacterized 24.8 kDa protein in cps region, ORF13.
Protein: ADPRH_STAAM
Sequence: METLKSNKARLEYLINDMRRERNDNDVLVMPSSFEDLWELYRGLANVRPALPVSDEYLAVQDAMLSDLNHQHVTDLKDLKPIKGDNIFVWQGDITTLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEIIRQQGRNEGVGKAKKTRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQHSLNHVAFCCISTGVFAFPQDEAAEIAVRTVESYLKETNSTLKVVFNVFTDKDLQLYKEALNRDAE
What is the function of this protein?
ADP-ribose glycohydrolase that hydrolyzes ADP-ribosyl-cysteine bonds (By similarity).  Specifically reverses the SirTM-mediated mono-ADP-ribosylation of GcvH-L (SAV0324), by releasing ADP-ribose from the target protein.  May be involved in the modulation of the response to host-derived oxidative stress.
What are the official names of this protein?
Protein-ADP-ribose hydrolase, SpyMacroD.
Protein: RL16_ACIAD
Sequence: MLQPKRTKFRKVQKGRNTGLAHRGSTVSFGSIAIKATERGRMTARQIEAARRTISRRIKRGGKIFIRVFPDKPITEKPLEVRMGNGKGNVEYWVCEIKPGKILYEIEGVNDELATQAFKLAAAKLPFKTTIVTRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DNJC8_RAT
Sequence: MAASGESGASGGGGSTEEAFMTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTNVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQRE
What is the function of this protein?
Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells.
What are the official names of this protein?
DnaJ homolog subfamily C member 8.
What are the subcellular locations of this protein?
Nucleus.
Protein: DJC21_MOUSE
Sequence: MKCHYEALGVRRDASEEELKKAYRKLALRWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAWYDNHREALLKGGLDGEYQDDSLDLLHYFTVTCYSGYGDDERGFYAVYRVVFELIAKEELECMSEGDVEDFPTFGDSQSDYDTVVHPFYAHWQSFCTQKNFSWKEEYDTRQASNRWEKRAMEKENKKIRDRARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLAEQYREQSWMTMANLEKELQEMEARYEKEFGDGSDENEVEDQEPRNGLDGKDSEEAEEAELYQDLYCPACDKSFKTEKAMKNHEKSKKHREMVALLKQQLEEEEEQFSGVQMDENVLNANSEEEMEDTPKQKLSKKQKKKKQKSAQNFDDNFNENGTEEGGKIAPEKTKSNEDNAKELENRPQENTCITETTEACEDPKSEAKSVPKSKGKKTKDVKKSVKAPAEAQPVSDVLISCATCHSEFPSRNKLFDHLKATGHARAPSATASLNSVTRNKKEKRRSR
What is the function of this protein?
May act as a co-chaperone for HSP70.  May play a role in ribosomal RNA (rRNA) biogenesis, possibly in the maturation of the 60S subunit.  Binds the precursor 45S rRNA.
What are the official names of this protein?
DnaJ homolog subfamily C member 21.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Within the nucleus, localizes primarily to the nucleolus.
Protein: CNTP5_HUMAN
Sequence: MDSLPRLTSVLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSPAQLNWRVGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGSMEQLEAVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLDESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYGDRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCGFMVDSDVNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHKQSHRTSQMKEKEYPENLDSSFRNEIDLQNTVSECKREYFI
What is the function of this protein?
May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
What are the official names of this protein?
Contactin-associated protein-like 5, Cell recognition molecule Caspr5.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RUBR_METTH
Sequence: MAAIKSEVSAMKRYKCRVCGYIYDPEKGEPRTDTPPGTPFEDLPETWRCPSCGAKKKMFKPLD
What is the function of this protein?
Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide.  Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule (By similarity).
What are the official names of this protein?
Probable rubredoxin, RD.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
Protein: LARC_LACPL
Sequence: MQTLYLDAFSGISGDMFLGALLDLGLDFEQLKTELAKLHVHGYELTQQREAQSSIYGTSFDVQVAGGKDHGFVEHHHHQHEAGHHHDHEARHLADIEALIDGSDLSDTVKHHAKAIFMEIAQAEAAVHHMPLAEVHFHEVGALDSIVDIVGCCIGLELMQIDTIMASPLSDGSGFINVAHGQMPVPVPAVMQMRVGSAIPIQQRLDVHTELITPTGMGLVKTLVREFGPLPENAVPTRVGYGFGKRDTGGFNALRAVLFEKKKLSQQIVNRTADAVLMIEANLDDQTGEGLGYVMNQLLTAGAYDVFFTPIQMKKDRPATKLTVLGNVNDKDLLTKLILQETTTIGVRYQTWQRTIMQRHFLTVATPYGDVQVKVATYQDIEKKMPEYADCAQLAQQFHIPFRTVYQAALVAVDQLDEEA
What is the function of this protein?
Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex).  Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor.  Is required for the activation of the lactate racemase LarA.  May also be involved in the activation of other nickel-pincer cofactor-dependent enzymes.
What are the official names of this protein?
Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein, P2TMN nickel insertion protein, Lactate racemase accessory protein LarC, Lactate racemase activation protein LarC, Lactate racemase maturation protein LarC, Lactate racemization operon protein LarC, Nickel-pincer cofactor biosynthesis protein LarC.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: ULK4_HUMAN
Sequence: MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRPEITNWVRLTREIKHKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKAFAGADQESSVEDLSLSRNTMECSGPQDSKELLQNSQSRQAKGHKSGQPLGHSFRLENPTEFRPKSTLEGQLNESMFLLSSRPTPRTSTAVEVSPGEDMTHCSPQKTSPLTKITSGHLSQQDLESQMRELIYTDSDLVVTPIIDNPKIMKQPPVKFDAKILHLPTYSVDKLLFLKDQDWNDFLQQVCSQIDSTEKSMGASRAKLNLLCYLCVVAGHQEVATRLLHSPLFQLLIQHLRIAPNWDIRAKVAHVIGLLASHTAELQENTPVVEAIVLLTELIRENFRNSKLKQCLLPTLGELIYLVATQEEKKKNPRECWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQSQGFITGEIGPILWYLFRHSTADSLRITAVSALCRITRHSPTAFQNVIEKVGLNSVINSLASAICKVQQYMLTLFAAMLSCGIHLQRLIQEKGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREMLLLSCQARLVMYIERDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVKQLKLCLPLMPVVLHLVTSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTASEEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVEWRLFSLRLLSETTSLLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNPTFTRLVEESKLIPLIFEVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSHICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIVRLALQAQKSGSGEDPQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENVEIFAHLLTSKEDPKEQKLLLRILRRMITSNEKHLESLKNAGSLLRALERLAPGSGSFADSAVAPLALEILQAVGH
What is the function of this protein?
May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.
What are the official names of this protein?
Serine/threonine-protein kinase ULK4, Unc-51-like kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
Protein: LIPA_NEIG1
Sequence: MSEIKTDDPKRGIKLRGADKTARIPIKVVPLQEKLKKPEWIRAKLPSRKFFEIKDILREQKMHTVCEEASCPNIGECFSKGTATFMIMGDICTRRCPFCDVGHGRPNMLDPDEPKNLAESVKAMNLRYVVITSVDRDDLRDGGAQHFADCIKAIRETSPNTKIEILVPDFRGRLDIALKILAETPPDVMNHNLETHPSLYRKARPGANYQHSLDLLKRYKEMMPHIPTKSGIMVGLGETDEDVREIMRDMRAHNIEMITIGQYLQPSDGHLPVLRYVTPEQFKIFEKEAYELGFTNAAIGAMVRSSYHADEQAAEALRESHGGCGHH
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SQS1_KLULA
Sequence: MAKRHKHYNARGGGKSKSKKSKPHGESRQRKNHRGGTSINRNRSELLLGGGDLMNPHQVEDYYFGSTAKKSSLRSGGFRPGRLTEADELDTGRLPSRKRPVEFIKAKELYDPSHDLILKLVKKNQHFDEPNSDGYNSSQSVSLREEEQDGEDEQQDVDTQEIPSKNTTVKIRSDNVVSENGDSESNSSANDAELFYVDMEGEEKTADNYIKTVDVDVQERSLKLNDCTEFQPTLRVGNVELNLKDGGSGSIEVDKPKSSYHPFHSYIQNVMENVQNYDSDDDFDENGNDVEQSFSISSDYEFESSEELITTGGTIEQFDSSMKSLTIEEIPGKTITASLTTKDISQGNSDNSSGDESFGFCEDDFEGSIGKVFVSNIRIGAGTHSYHVSCHEIYGDSEPRWVDDEMMNEIIAEMGLPEHRFRAYYKHLHKSFIEEEEEPEEYADIPFDDDDSDDSTADQCEPFAEDDLGEDLDDLVSYALKYNKQRKIEYHTTSLDIRGKGRNKHLIFDQTAGMDEDIKLMLQNKFATRQINKTKKRRAKEDFLSQSHASSTDLLMKYPYGLHIQNIKDEFDAFYRNDRQSITFPPLDPHGNKIIGKFAYNYFMKASNIGKGKSTKVYVEKTKKTRFNKPAYHIISQLLRKRPVFMRIDQKAPTDTQSTFNRTVRLKVSKENFNISEGQIVGEDAPEIGIDNIGRRMLEKLGWNIGQGLGAHGNQGINEPILAKVKKNKSGLRHTSENQQ
What is the function of this protein?
May be involved in splicing.
What are the official names of this protein?
Protein SQS1.
What is the protein family that this protein belongs to?
Belongs to the SQS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PAKB_DICDI
Sequence: MEQSKRVSMMREKFEAQSNEAESSPPPNRKPPPPNKRVQTNGTSSLNSSGSSFVSPSPSPSPSPQQPVKRPLPSPGVNKQAPPALPTQPRPQQQQPEIPVRPTTPTRTPPNLINSNGTSGGSGFSSSSGNSGYSSSNNNNSNSNSSINMNGNHSNGLNGGSSNPVPMRKVSSPINIANGTTPPPPPQPTPSQQPQQSPSSASHNNTQHNIPSPPPLPNNKPKKLAPTAVPAGLGSIIGGPKTPAISPGSTSPSLGSSNGNIPISTTSTPITPTPPISVPLATSPNNSHKDSISNSNSNNNNNNNNNNNNNSSNATTSPPSPPVSNVGNKQDEEKKGFLSIFTNKKKNKDKKKEFSVGSPFNVKHNIHVNYHSVTGFEGLPKEWEVILQSSGITREDVVEHSEVVIDVLDFHMQQQQQQAQQEQQALMQKQMQQSGIPAHMLNNPKPPTIPIRDANKQPHNQLQPTPHQPPQHHHQQQPPQQHHHQQQQQQHNNNNNNNNNNNNNNNNQQSAQQQSAGILSQQQEQQLEEMMCGGAYDDEQYDLNNQPLPDETNVSLYDLVSQEDPTKLFGEGSTKIGEGAAGEVFVVTQLKTNNKVAIKKMPLNQQNMKLIVTEIGIMKSCRHQNIIDYIDSYLVGDSLWVAMEFMGGGCLTEILEQFNSVKLVEAQIAYVCAETLKGLAYIHSQHRIHRDIKSDNILLGSDGSVKLADFGYAAQLTKSKQKRVTIVGTPYWMAPELIRGQNYDRKVDIWSLGIMAMEMAESEPPYMSFPPLRALFLITTKGIPDLKDQNKWSDDFKDFVKKCLDKDVENRPEAKVLLNHPFLKTACNSNGLVPAIMEAKKAKEAHSKFSIH
What is the function of this protein?
Regulator of the myosin I component of the cytoskeleton: required for regulation of cytokinesis, phagocytosis and pinocytosis.
What are the official names of this protein?
Serine/threonine-protein kinase pakB, dPAKb, Myosin I heavy chain kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Membrane. Cytoplasm, cytoskeleton. Note=Mainly cytosolic but enriched at the leading edge of migrating cells and at macropinocytic and phagocytic cups, possibly due to binding to acidic phospholipids.
Protein: PSBO_PINPS
Sequence: LTYDEIQSKGGSTGYDNAVALPAGGR
What is the function of this protein?
Stabilizes the manganese cluster which is the primary site of water splitting.
What are the official names of this protein?
Oxygen-evolving enhancer protein 1, OEE1, 33 kDa subunit of oxygen evolving system of photosystem II, 33 kDa thylakoid membrane protein.
What is the protein family that this protein belongs to?
Belongs to the PsbO family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: RLA0_CHICK
Sequence: MPREDRATWKSNYFMKIIQLLDDYPKCFVVGADNVGSKQMQQIRMSLRGKAVVLMGKNTMMRKAIRGHLENNPALEKLLPHIRGNVGFVFTKEDLTEIRDMLLANKVPAAARAGAIAPCDVTVPAQNTGLGPEKTSFFQALGITTKISRGTIEILSDVQLIKTGDKVGASEATLLNMLNISPFSFGLVIQQVFDNGSIYNPEVLDITEETLHKRFLEGVRNVASVCLQIGYPTIASVPHSIVNGYKRVLAVAVETDYTFPLAEKVKAFLADPSAFVAAAPVVVETAAPAAAAAPAKEAPKEESEESDEDMGFGLFD
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0, 60S ribosomal protein L10E.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SYL_ACIAC
Sequence: MQDKYTPAEVERAAHSHWTARDAYRVTEDAGKKKFYACSMLPYPSGKLHMGHVRNYTINDMLTRYLRMNGHNVLMPMGWDAFGLPAENAALKNGVPPAQWTYDNIAYMKKQMQAMGLAIDWSREVATCDPDYYKWNQWLFLKMLEKGIAYRKTQVVNWDPVDQTVLANEQVIDGRGWRTGALVEKREIPGYYLKITDYAQELLDHVQVGNPNATLTGWPDKVRLMQENWIGKSEGVRFAFTHDIRGEDGQPIGDGRMYVFTTRADTIMGVTFCAVAPEHPLAAHAARSNPDVAAFIQECKTGGTTEAELATQEKKGVRTGLTVTHPLTDEPIEVWVGNYVLMGYGDGAVMGVPAHDERDFAFALKYGIEIKQVVLVDGETFDYHRWQDWYGDKQNGVTINSDNFSGLSYQEAVSAVAHALQEKGLGEKKTTWRLRDWGVSRQRYWGTPIPIIHCDEHGAVPVPEKDLPVVLPQDCIPDGSGNPLHKHEGFHAGVKCPVCGKAARRETDTMDTFVDSSWYFMRYCDPKNADAMVAGGADYWMPMDQYIGGIEHAILHLLYARFWTKVMRDLGLVKVDEPFTKLLTQGMVLNHIYSRRTDKGGKEYFWPHDVEHIQDEAGKITGARLKNAVGDLPAGTPIDYEGVGTMSKSKNNGVDPQELIEKYGADTARLYTMFTAPPEATLEWNDAAVEGSYRFLRRVWNFGVKLAGIDAAATEAAIQGAQSLQDVQFGKEAKALRLEIHTVLKQVDYDYQRMQYNTVVSGAMKMLNALEDFKSADAPGGLVALIEGFGILLRVLYPATPHIAHGLWSGLGYAGSLGDLLDAPWPQVDAGALMQDEIELVLQINGKLRGAIRVPSGADKAEIERIALASEDFHKHAAGAAPKKVVVVPGRLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDC2_ORYSJ
Sequence: MEGVGGGGGGEEWLRPMDAEQLRECGHRMVDFVADYYKSIEAFPVLSQVQPGYLKEVLPDSAPRQPDTLDSLFDDIQQKIIPGVTHWQSPNYFAYYPSNSSTAGFLGEMLSAAFNIVGFSWITSPAATELEVIVLDWFAKMLQLPSQFLSTALGGGVIQGTASEAVLVALLAARDRALKKHGKHSLEKLVVYASDQTHSALQKACQIAGIFSENVRVVIADCNKNYAVAPEAVSEALSIDLSSGLIPFFICATVGTTSSSAVDPLPELGQIAKSNDMWFHIDAAYAGSACICPEYRHHLNGVEEADSFNMNAHKWFLTNFDCSLLWVKDRSFLIQSLSTNPEFLKNKASQANSVVDFKDWQIPLGRRFRSLKLWMVLRLYGVDNLQSYIRKHIHLAEHFEQLLLSDSRFEVVTPRTFSLVCFRLVPPTSDHENGRKLNYDMMDGVNSSGKIFLSHTVLSGKFVLRFAVGAPLTEERHVDAAWKLLRDEATKVLGKMV
What is the function of this protein?
Involved in serotonin biosynthesis.  Catalyzes the decarboxylation of L-tryptophan to tryptamine, which is converted to serotonin by tryptamine 5-hydroxylase (PubMed:17763868).  May play a minor role in serotonin biosynthetis during senescence.  Accumulation of serotonin attenuates leaf senescence (PubMed:19439571).
What are the official names of this protein?
Tryptophan decarboxylase 2.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: RS16_EDWI9
Sequence: MVTIRLARGGAKKRPFYQVVVTDSRNARDGRFIERVGFFNPIATGSAEGLRLDLDRVSHWVSQGATVSDRVAALIKEAQKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NIKD_RHORT
Sequence: MRNDGLRIEGLTIATLGAHPLMLVEGVGLEVRRGRILALVGASGSGKSLTCAGALDVLPAGVRRLSGRVLLDGEEQALAGLKGRHVASIMQNPRSAFNPVRTMRAHGVETLKALGRHDRRSEAVLLQALEGVGLEDPGRVLGLHAFEMSGGMLQRMMIALALLTEAPFLFADEPTTDLDLVVQARVLSLLEGVVAERGLGLLIVTHDMGVVARLADDVAVMAQGRIVESGPVGEIFHRPRHDATRALVAAHLSLYGLEGVA
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CR43_RANCA
Sequence: GLWQKIKNAAGDLASGIVEGIKS
What is the function of this protein?
Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes.  Each caerin displays a different antimicrobial specificity.
What are the official names of this protein?
Caerin-4.3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.