PharMolix/UniProtQA huggingface dataset:
Protein: CARB_BACC4
Sequence: MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTATADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLDECGVEILGTKLSAIEQAEDRDLFRTLMQDLNEPTPPSEIIHNLDEAYGFVNEIGYPVIVRPAFTLGGTGGGICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGCKEIEYEVMRDSNDNAIVVCNMENIDPVGVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRWPFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELDHLKELDKETMKKRIIKADDERLFIVAEAIRQGVTKEEINEWCEMDFFFLQKVENIVNMEREVKANVGNMEVLQIAKEMGFSDHYIAAAWNKTEREIYDMRKENNMMPVFKMVDTCAAEFESATPYYYSTYADENESIVTDRKSVVVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIIINNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLEEHGVKILGTSLEDLDRAEDRDKFEAALTKLGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYVLGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVFIPGIMEHIERAGVHSGDSIGVYPPQSLSEKLKEQIIEHTIALGKGLNIVGLLNIQFVVFKDQVYVIEVNPRASRTVPFLSKITGVPMANVATKVILGQDLVEQGYGTGYHPEEKEVYVKAPVFSFAKLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVASGINIPTHGSVIITVADKDKEEAMEIAKRFHEIGYNLLATAGTAQSLEEQNIPVQVVNKIDSEDYNLLDIIRQGKAQFVINTLTKGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHSMKEITQTKRHEVVHA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: PLD4_MOUSE
Sequence: MDKKKEHPEMRIPLQTAVEVSDWPCSTSHDPHSGLGMVLGMLAVLGLSSVTLILFLWQGATSFTSHRMFPEEVPSWSWETLKGDAEQQNNSCQLILVESIPEDLPFAAGSPTAQPLAQAWLQLLDTARESVHIASYYWSLTGLDIGVNDSSSRQGEALLQKFQQLLLRNISVVVATHSPTLAKTSTDLQVLAAHGAQIRQVPMKQLTGGVLHSKFWVVDGRHIYVGSANMDWRSLTQVKELGAIIYNCSNLAQDLEKTFQTYWVLGTPQAVLPKTWPRNFSSHINRFHPLRGPFDGVPTTAYFSASPPSLCPHGRTRDLDAVLGVMEGARQFIYVSVMEYFPTTRFTHHARYWPVLDNALRAAALNKGVHVRLLVSCWFNTDPTMFAYLRSLQAFSNPSAGISVDVKVFIVPVGNHSNIPFSRVNHSKFMVTDKTAYVGTSNWSEDYFSHTAGVGLIVSQKTPRAQPGATTVQEQLRQLFERDWSSHYAMDLDRQVPSQDCVW
What is the function of this protein?
5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (PubMed:30111894).  Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor (PubMed:30111894).  Involved in phagocytosis of activated microglia (PubMed:22102906).
What are the official names of this protein?
5'-3' exonuclease PLD4, Choline phosphatase 4, Phosphatidylcholine-hydrolyzing phospholipase D4, Phospholipase D4, PLD 4.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Nucleus. Early endosome. Cytoplasmic vesicle, phagosome. Note=Activation of microglia induces translocation of PLD4 from the nucleus to the phagosomes.
Protein: RSMC_PSEF5
Sequence: MDTRSEVLLRQAELFQGSLLLAGLAADDLLGRLPNARGWSWHAGDQAALEARFPGRSHFGVDAPAQSFDSAVLFLPKSKDLTDYLLNALASRLAGRELYLVGEKRSGVESAAKQLNPFGKPRKLDSARHCQLWQVTVANAPEPLTLQSLAQEYELPLAEGPLKVISLPGVFSHGRLDRGTALLLEHLDHLPAGHLLDFGCGAGVLGATVKRRYPDSRVTLLDVDAFAAASSRLTLAANGLEAEVLTGDGIDAAPMGLNGILTNPPFHTGVHTDYQATENLLRKAAKHLQKGGELRVVANSFLRYQPLIEEHLGPCAIKAEGQGFRIYRAKRG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_PSYA2
Sequence: MIGLISGQVQYLMAPTACVMTTSGIGYDIELPLPSFCQLRLNEQASIWTHFHVREDAQLLYGFIDRKERDVFRQLIKINGVGAKMALAMLSAMSAAELKMHVEQESETALTRIPGIGKKTAQRLLIELKDKLKNIEVDNSNLEFAIQPAPISAEDSIIAEVEGALMSLGYKEKEAQQAIKAAKSNGETFADTQSLLKATLQQFQSFK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TRPA_BRUO2
Sequence: MTTRIDTKFAELKAEGRPALVTYFMGGDPDLETALKVMKALPKAGADVIELGMPFSDPMADGPAIQAAGLRPLNAGQTLAKTLYMAAEFRKEDDTTPIVMMGYYNPIYVYGVERFLTDAKASGVDGLIVVDLPSEMDAELCIPAMKAGINFIRLTTPTTDDKRLPKVLHNSSGFVYYVSMNGITGAAIADTAKVGEAVRHIKKSTDLPICVGFGVKTPEQAAAIATHADGVVVGTAIVNAIAGELDEKGKVKGDPVAAATRLVHALAESVRATRLEAAQ
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: HIS7_LEPBA
Sequence: MLRNMVESRKTSETDIRLDLNLRGSGVYAFDTEIPFFEHMLSHIAKHGLIDMDLKLRGDIGIDCHHSVEDTAILLGQMIHTQLGDKKGIFRYGNFTLPMDEVLTTVAVDLGGRFYFKYTGPALDGKFGIYDAELTLEFLQKLALNAKMNLHVVVHYGENRHHIHESIFKALGKALRQAIAIDTSAKDQIPSTKGMLE
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_FRATT
Sequence: MENKSNSQILFAEAQQYIPGGVNSPVRAFKSVGQEFPRFIKFAKGAYLYDVDWNKYIDYIGSWGPMILGHCDDDVLEAIQCQVKNGLSYGAPCKQEVDLAKKIIELMPNIEQVRFVNSGTEATMSAIRLARAYTCRNKIIKFEGCYHGHADEFLVAAGSGALSLGQPNSPGVPEDVVKDTLVASFNDMESIQALFEKYKDEIACIIIEPIAGNMNMIFPQDDFLAKLRAICDQNSSLLIFDEVMTGFRVALGGAQSIYNVKPDLTTLGKVIGGGMPVGAFGGRKEIMQKVSPAGPVYQAGTLSGNPIAMTAGIKTLEKISQPGFFDELGAKAQKLVDGLNEAAKAYDFNFHAKCLGGMFGLFFCSDKIAVNTFVDLGKTNLKMFNQFFAYMLDNGVYLAPSAYEAGFISIAHSDEDIEKTIYLAKKFFQEN
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRF3_CAEEL
Sequence: MMGRNDDAFHPLLHSTPESSVKIPVPLVSVGRESSQSKGNMKTAILIWLTLQNSIHTLLIRYSRAREVDAMFVSTVAVWLTEVIKCFICLFLVAQEETPRRFIHALRTQILEQPYDTLKVCIPAMIYIVQNNLFYVAASHLDAATFMITSQLKIFTAAIFTVIILRRSLNRTQWFALAVLFVGVSLVQLQGTKAKESSGESPFVGFVAVVVACCLSGFAGIYFEKILKGSAPVSLWMRNVQMAVFSIPASFSAIYMQDSKTVNEYGLLYGFDSIVWLTVLWYGVGGLSVAVCIKYADNIAKNFATSVAIILSTIGSIFLFDFIPSFTFLLGASLVIFSIFLYSSHQSMVAALGRLRGEIPSTKEAFCL
What is the function of this protein?
Acts as a transporter of both UDP-galactose and UDP-N-acetylglucosamine into the Golgi lumen (PubMed:15123614, PubMed:15452127).  Apparently transports UDP-galactose and UDP-N-acetylglucosamine simultaneously, and independently, by an unknown mechanism (PubMed:17652078).  Functions redundantly with nucleotide sugar transporter nstp-4 (PubMed:17652078).  May be involved in gonadal development (PubMed:17652078).
What are the official names of this protein?
UDP-galactose/UDP-N-acetylglucosamine transporter srf-3, Surface antigenicity abnormal 3.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: LTX2A_NEOGO
Sequence: LLKELWTKMKGAGKAVLGKIKGLL
What is the function of this protein?
Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria.  Is inactive against yeast, erythrocytes, and insects.
What are the official names of this protein?
U1-poneritoxin-Ng2a, U1-PONTX-Ng2a, Poneratoxin, Ponericin-L1.
What is the protein family that this protein belongs to?
Belongs to the ponericin-L family.
What are the subcellular locations of this protein?
Secreted.
Protein: H4_MEDSA
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRD
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS21_SYNSC
Sequence: MSQVTVGENEGIESALRRFKRSVAKAGIFSDLRRIRHHETPVEKYKRKLKQRSRNRRR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: FRIH_RABIT
Sequence: AINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPEYDDWESGLNAMECALHLEKSVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKSIKELGDHVTNLRKMGAPESGMAEYLFDKHTLGHSDNES
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  Also plays a role in delivery of iron to cells.  Mediates iron uptake in capsule cells of the developing kidney (By similarity).
What are the official names of this protein?
Ferritin heavy chain, Ferritin H subunit.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: Y1373_HAEDU
Sequence: MYIVMNSNFCAIYKSMSKEGMFLYIAQRDKFNAVPEQLLQMFGKPQFVMLFNLAGEKPLKQVNNQDVLLAIKTQGFFLQISPPAENLLKQFLIQKGEKK
What are the official names of this protein?
YcgL domain-containing protein HD_1373.
Protein: LACB2_CANLF
Sequence: IVIPRTMEDLDLQKVAGTWHSMAMAASDISLLDSETAPLRVYIQELRPTPQDNLEIVLRKWEDNRCVEKKVFAEKTELAAXFSINYVEENQIFLLDTDYDNYLFFCMENANAPQQSLMCQCLARTLEVNNEVIGKFNRALKTLPVHMQLLNPTQVEEQCLV
What is the function of this protein?
Primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
What are the official names of this protein?
Beta-lactoglobulin-2, Beta-LG-2, Beta-lactoglobulin II.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NANA_ECOHS
Sequence: MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPGVGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQLMQERG
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OFT24_ARATH
Sequence: MGTWKNKNSNKKNRVSYISVPAQIINSVSSSSLHKFLDNKSSKKNTSKFFFNLRNPKLWAFSLFLLSILGISLRLGLCLSHFGSGDHESQLQSSDSNGSPKSHMGFAYIRSSTTQVEISNAKDRSLDMGVEKNETFGGHQSHLIIPNGNGHDDKNYDFWKQPDGLGYKPCLDFSIEYRRESKKILVERRKYLMVVVSGGLNQQKIQIVDAVVIARILGAVLVVPILQINLIWGDESEFSDIFDLEQFKSVLANDVKIVSLLPASKVMTRPSEDGSMPFNASPQWIRSHYPKRFNREGVLLLRRLDSRLSKDLPSDLQKLRCKVAFEALKFSPRVMEMGTKLAERMRSKGPYIALHLRMEKDVWVRTGCLSGLSSKYDEIVNIERIKRPELLTAKSSMTSNERKLAGLCPLNAKEVTRLLRALGAPRDARIYWAGGEPLGGKEALKPLTSEFPHLYNKYDIALPLELKPFAKRASIMAAIDYIVCKESDVFMASHGGNMGHAIQGHRAYEGHKKIITPNKRHMLPYFVNSSLTETEFEKMIKKLHRQSLGQPELRISKAGRDVTKYPVPECMCNQSNTTI
What are the official names of this protein?
O-fucosyltransferase 24, O-FucT-24, O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: Y1008_PYRHO
Sequence: MIILLVGMPGSGKGEVAKAFRRRGIPVISMGDAIREEAEKRGIPKTPEGLKYVSLKVREELGPGAVAILTIPKVRGIIKRKGIVVIEGVRSPAEVQEFRREFKNERVIILAIHSPPKVRFERLRRRGRSDDPKTWNEFLDRDKKELGFGIGEVMSLADYVILNNCTFNEFQRKIEKVVSKILSNWP
What are the official names of this protein?
UPF0200 protein PH1008.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: FORC_DICDI
Sequence: MKIRVELINGNEHRTSSTPQQPQQNPSVSHIFDGETAVKDHIKVLLTHFKIPVDKVSSYALQNPFTLAYVEDSFLTPERLVEAEKSYFILRMKPHAIADRVVDQLTKIEPTSPHIKDTIFNIRYQMKDVEYVEEFIIKGGINQLLAVIIKSRGNTQSYALTALRCFMGYNSGLEEVMSRPQLIDKLYSLVCSVGVLPSVCRQAIELLFCVCNFDGFQLVHRSAKNHAQETSTPAYSNLITLLSSGDMETQLNTLTLFNCLLDNAPNPRKSEKLLSRWQQLGIIKILKSQEHVTHSDFRTQIARFQANSGFGIDGSGRKRTLTRQLSTQELEFQLHQFREQQPLISLLTSELKFLRNAIKSAIENGSYINYRAPTERYDEYSQRKLEMIGDSPTNLQFLKRNDKFTNAFRKSMYVRSPNTSDLFDSSTLEDTYDGNNDTNSCTSISTSSTPIHISQPTTLIVPSTTPNHPPQQSQQTPPLQLQKEKEKEKEKEKEKEKEKEKEQQQQQQQSNKQSTPKPNLSCLLSPITISNTLNNNNNNNNNTNNNIIKSNNNNNNNNCTIKDLSPIVKSEKSNEDEIHEISLNGASSNHEEPIKYKLQPTKSPITPSKRMKPLHWTRILNSQFEGKKTIWNSYLPEVTFEEELFVDLFSLYTERIVSFSGSPVGSGTSISGGGPIKSKPIQKVISVLSQKRSNAIIVMCGKLPSDDILIRAIRNLDSNKLSLDGVSSIISNFPTSEELASIHELHSNEVILDKPERWCLMIDGFPMIKHRLRCWEFMLKIEDSLKSIIESIDTVLLACKELRTSITINCLFSLLLQLGNYLNGGHLYRGQSDGFNLESLSKMIEIKDNSNSGSLLDFAIKTLYQQSPMKGNSNTSIHLELAHVPNASLINFTDVGTSVSKLLQDYSEIVLMSDEIQQTTDKDDPFLDIVPKFMGTILLILKNLQTKFLETEKYLFETIDYFNPTNQTLQQYQQQQYQQYQQQQFQQNIINNNNNNNNNNSNNNNNNISGNTTTTTTTTTTTTTGSIINNNNNNNNNNNNSNNNIINNNNSQSNLQSLLHPQYYLSNSSSSSSSSYKITPPLSSSLSITSQEWNQQKFTCEKFFTLFSTITTAFKKSPSKRLSQKGFGLKISNSDDPMAVIIEALKTGSPNDMVKRAF
What is the function of this protein?
Formins play an important role in the nucleation of actin and the formation of linear actin filaments.
What are the official names of this protein?
Formin-C.
What is the protein family that this protein belongs to?
Belongs to the formin homology family. Diaphanous subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Note=Found localized to the crowns, which are macropinocytotic cups rich in F- actin.
Protein: SURA_METCA
Sequence: MKISSFRKGRWLGALALFAVVCWSMADAAVDRIVAVVDDGVILESELVRKVDEIKRSLRASRASLPPDSVLVRQVLERMIVDKIQIQMAEKMGIQVDDDTLRMAVSQIAQRNNLTPDQFRRSLAREGIDYGDFLDQVRSEIAMGRLRASQINNQIKISDREVEHYLEAQGGSGAVADREYRLGHILIATPREASPDEVKKARERADRVVKELKAGLDFKDASIRYSDDPQALEGGDLGWRKLSEIPSHIAEVVGGMKDGEVSDPIRSPGGYHIVKMLAMRGVGEAKLTKTHVRHILIRPNEVLSDEDAKNKLLALKTRIENGDDFAELARGHSDDKGSAIKGGDLGWVKPGALVPPFEEAMNALDENQLSDPVQTQFGWHLIQVLERQESSDTNEVLKNRARDELFKRKVDEETELWLRKIRDEAYVEIRLDETPASPGEDAPAGEDSPETFMR
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: RUTF_ECOBD
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: RL5_STAAR
Sequence: MNRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEARELLANFGMPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y007_MYCTO
Sequence: MTAPNEPGALSKGDGPNADGLVDRGGAHRAATGPGRIPDAGDPPPWQRAATRQSQAGHRQPPPVSHPEGRPTNPPAAADARLNRFISGASAPVTGPAAAVRTPQPDPDASLGCGDGSPAEAYASELPDLSGPTPRAPQRNPAPARPAEGGAGSRGDSAAGSSGGRSITAESRDARVQLSARRSRGPVRASMQIRRIDPWSTLKVSLLLSVALFFVWMITVAFLYLVLGGMGVWAKLNSNVGDLLNNASGSSAELVSSGTIFGGAFLIGLVNIVLMTALATIGAFVYNLITDLIGGIEVTLADRD
What are the official names of this protein?
Uncharacterized protein MT0007.
What is the protein family that this protein belongs to?
To M.leprae ML0007.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TBD2B_HUMAN
Sequence: MPGAGARAEEGGGGGEGAAQGAAAEPGAGPAREPARLCGYLQKLSGKGPLRGYRSRWFVFDARRCYLYYFKSPQDALPLGHLDIADACFSYQGPDEAAEPGTEPPAHFQVHSAGAVTVLKAPNRQLMTYWLQELQQKRWEYCNSLDMVKWDSRTSPTPGDFPKGLVARDNTDLIYPHPNASAEKARNVLAVETVPGELVGEQAANQPAPGHPNSINFYSLKQWGNELKNSMSSFRPGRGHNDSRRTVFYTNEEWELLDPTPKDLEESIVQEEKKKLTPEGNKGVTGSGFPFDFGRNPYKGKRPLKDIIGSYKNRHSSGDPSSEGTSGSGSVSIRKPASEMQLQVQSQQEELEQLKKDLSSQKELVRLLQQTVRSSQYDKYFTSSRLCEGVPKDTLELLHQKDDQILGLTSQLERFSLEKESLQQEVRTLKSKVGELNEQLGMLMETIQAKDEVIIKLSEGEGNGPPPTVAPSSPSVVPVARDQLELDRLKDNLQGYKTQNKFLNKEILELSALRRNAERRERDLMAKYSSLEAKLCQIESKYLILLQEMKTPVCSEDQGPTREVIAQLLEDALQVESQEQPEQAFVKPHLVSEYDIYGFRTVPEDDEEEKLVAKVRALDLKTLYLTENQEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLISISFGDLNPFPLRQIRNRRAYHLEKVRLELTELEAIREDFLRERDTSPDKGELVSDEEEDT
What is the function of this protein?
GTPase-activating protein that plays a role in the early steps of endocytosis (PubMed:32623794).
What are the official names of this protein?
TBC1 domain family member 2B.
What are the subcellular locations of this protein?
Early endosome.
Protein: NAR1_KLULA
Sequence: MSALLRDADLNDFISPGLACVKPAQPQKVEKKPSFEVEVGIESSEPEKVSISLQDCLACAGCITSSEEILLSKQSHKVFLEKWSELEELDERSLAVSISPQCRLSLADYYSMCLADLDRCFQNFMKTKFNAKYVVGTQFGRSISISRINATLKDRVPENEGPLLCSVCPGFVLYAEKTKPELIPHMLDVKSPQQITGNLLKQADPTCYHLSIMPCFDKKLEASREECEKEVDCVITPKEFVAMLGDLSIDFKSYMTEYDSSKELCPSGWDYKLHWLSNEGSSSGGYAYQYLLSLQSSNPESDIITIEGKNSDVTEYRLVSKSKGVIASSSEVYGFRNIQNLVRKLSQSASVKKRGIKVKRRGQSVLKSGETSEKTTKVLTADPAKTDFVEVMACPSGCINGGGLLNEEKNANRRKQLAQDLSLAYTKVHSVNIPDIVHAYDDKSNDFKYNLRVIEPSTSSDVVAVGNTW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: FEOB_SALPA
Sequence: MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFATTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQQVRIDVDALSTRLGCPVVPLVSTRGRGIEALKLAIDRHNANDNVELVHYAQPLLREAGFLADAMAQEMPLQQRRWLGLQMLEGDIYSRAYAGEAAQNLDTSLARLKDEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTRAVDKIILNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDAGSVAIFIHGIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYVLGIVMAVLTGLMLKHTIMRGEASPFVMELPVYHVPHIKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEAFNPADFHLGDELLGAVDDTWQSLKDTFSLSVLANPIEASKGDGEMATGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMSFSILWGLNIAYSLATLFYQVTSFSQHPTYSLICILAVIVFNVVVLSLLRRARSRVDIELLATRKSVTSCCSGTAGNCH
What is the function of this protein?
Probable transporter of a GTP-driven Fe(2+) uptake system.
What are the official names of this protein?
Fe(2+) transporter FeoB, Ferrous iron transport protein B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TSC3_KLULA
Sequence: MAAEKIYEPYKKSRGTMIYTPTNQQMSRGGIGEKLADFVKNLYWVYYIHLPFYLMTSLDAFCLHTIFLVVVSLSLFGLLKYIFL
What is the function of this protein?
Stimulates the activity of serine palmitoyltransferase (SPT).
What are the official names of this protein?
Serine palmitoyltransferase-regulating protein TSC3.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SVF1_YEAST
Sequence: MLKWIKGGISAVTGMAEPEYGKDYIHSVADRVKNKQPYRETSREDFFWQAPDHTNVESVIFYFSDLKTGIFGFAQVIHSNIIGLHTASQFTFRIFDSKNPEDLNIWTSTKLENFYIEGPNFYADNLSVELSEDGESYHIQSSVCDLSVVDLHIRRLTPGAKIGDDPATYYGNNINEPWGSMRHVFWPRNACHGTIKVKKEVIPESDEEESSADEDDNEDEDEESGDSEEESGSEEESDSEEVEITYEDRTITFKEEDPAISTFIMAFQGMKPHHAAKAWNFMFFHSEKYSAVLMEFTTPKSYANTKISAGIITDDKEVLAMTTNNLVEHLNSEIDSVGWKVPKDIKITFKGINTKVKDEQLESENGTEQALQGEDEKEDEKEDEEEEEYKNVAEENKICAVVEGPLNNLVERIDVMGEIPSFVKNIVSGVAGTKPFIYQYADPKSSTLQINGGEKIHGVAWTEVTFISESDVISEESYNEA
What is the function of this protein?
Required for survival in response to oxidative stress.  Involved in the diauxic shift.
What are the official names of this protein?
Survival factor 1.
What is the protein family that this protein belongs to?
Belongs to the SVF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ALO_NEUCR
Sequence: MATESNPALASLPSNVREIIELASQRDGGIPFRAKTAHVHRTWAGTFTSLPELYIQPESVSEIQKVVRLARHARRRVTTTGCGHSPSDITCTSSWLVNLDNFNKVISVDHLTGLVVVQAGIRLYQLSDELDRRGLALPSLGSINEQSIAGAISTGTHGSGIKHGLVGESITELKITLANGETLSCSPEDKPDLFRAALISLGALGIITEVTFKAVPAFSLAWSQAIDSDKRIFEKWEKDLWSQAEFVRIWWFPYMRRAAVWTANVVDPVDLKTGAVKHREPPTSYYDSWLGYYVYHNLLALSRWIPRITPWIEWFVFGMQYGFKNGEVTRIGAVQPSQKAFLLNCLYSQSVNEWAIPLHKGPEALQRLGAWLQNLKPGDPGYVEHGIPYSAEGLWVHSPVEVRASDSTVYTSREANTRPFLDPTQSDGPTLYLNAIMYRPYHREPTYNATERYYLGFEWLMRELGGKPHWAKTFTATQADLARWYGDDFQRWGAVRESVDPEGMFVGPWHRRYLLEPLQRDRLLPLEEIQQTTKKVPARQGGGIEVIGIQNLVAPN
What are the official names of this protein?
Putative D-arabinono-1,4-lactone oxidase, ALO, L-galactono-gamma-lactone oxidase.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion membrane. Note=Membrane-embedded.
Protein: RECR_RHOJR
Sequence: MYEGPVQDLIDELGKLPGVGPKSAQRIAFHLLSVEPPEIDRLKNALQRVRDGVQFCVVCGTVSDKEHCRICADPRRDRTVICVVEEPKDVQAVERTREFKGRYHVLGGALDPLSGVGPDQLRIRELLARIGNQEDGVDVSEVIIATDPNTEGEATATYLVRMLRDFPGLTVSRLASGLPMGGDLEFADELTLGRALSGRRTL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.