PharMolix/UniProtQA huggingface dataset:
Protein: TSSK2_MOUSE
Sequence: MDDAAVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHRSIIKTYEIFETSDGRIYIVMELGVQGDLLEFIKCRGALHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDGSGRIVLSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIKKMLRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILSHSWLQPPKPKAMSSASFKREGEGKYRADCKLDTRPGSRPEHRPDHKLATKPQQRMLVTPENEDRMEDRLAETSRAKDHHISGAEVEKAST
What is the function of this protein?
Testis-specific serine/threonine-protein kinase required during spermatid development.  Phosphorylates 'Ser-281' of TSKS and SPAG16.  Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm.  During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
What are the official names of this protein?
Testis-specific serine/threonine-protein kinase 2, TSK-2, TSK2, TSSK-2, Testis-specific kinase 2, Serine/threonine-protein kinase 22B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Present in the cytoplasm of elongating spermatids. In spermatozoa, localizes in the equatorial segment, neck, the midpiece and in a specific sperm head compartment. In spermatids, concentrates in centrioles during flagellogenesis. Localizes in the tail and acrosomal regions of epididymal sperm.
Protein: Y1717_SYNY3
Sequence: MLESKLENLRQFFGELDRALIAYSGGVDSTLVAKVAYDVLGQNAVAITAVSPSLLPEELEDAQAQAQWIGIAHELVQTNEMANPNYTANPENRCYFCKSELHDTLQPLALALGYNYVIDGVNGDDLRDYRPGIQAAKERGGRSPLAELQISKLEVRQISQLLGLPWWDKPAQPCLSSRFPYGEEITVEKLQRVGRAEIYLRRLGYNQVRVRSEQNLARIELPPEQIQQFVQDVSLGELVQTFQNFGFLYVTLDLEGYQSGKLNRVLTK
What are the official names of this protein?
Uncharacterized protein slr1717.
What is the protein family that this protein belongs to?
Belongs to the LarE family.
Protein: UBP7_CAEEL
Sequence: MQCSPDPEDLLIVPTHDIPSYDESLDPFGPEGHLSLDIDCFSKFMSRSDNRIMSKPIIVRGIPWRILAICRNQQGSRHSMNSRVNRSNFNFGFFLQCNNDELLQKRGMWRCYGTAVLEVLNADGPSIQKKIHHSFHNTEVDWGFSNYDQYDTLCNPKDGYVVNDTIKLRCRFTADVPTGANYMWDSKRHTGCIGLRNQGATCYMNSILQSFYFTTGFRRAVYNMDVGTEPNESNIVLAMQRVFYELQMASEAVETNSLTRAFGWDKLDAFNQHDVQEFCRVLLDNLETKMKGTSEEKSIPNLFRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFEAYTTSEILDDENKYDAGDHGLQRAEKGVKFVELPPILHVQLMRFQYCGVEQKINERFSFPEKMNLASCCELGPMLTEEDCVYSLHAVLVHSGEFHGGHYVTYINVNLHESAVDPTSSAKWCKFDDDVVSRTTTDDAIVSNFGGEKTMNSSAYMLVYVRDNAIDQFLAPIPDSQIPQSVSRTFEMERLHRNREKKKLEEEQLCMGIVLVTPDIVASNHSFDLVDQSIVHDSIPHETVWKHMFTAELYQFVHDRLFEKSAMQKIDMFDSDDEARQARRDNLRRIKSKKFNFRLWRMTDSYSLERTTQKLTSRLRPSEFIDCKTDTRLDTLLSQDFETIYVEFSNNIERPLCEYDTARDLLFFVKYYDTMTDKFTIIGHTMFDCHKRFNLYRSMLCEMIGLPADTELKYYMEHAASYLELVDLTQNYSIGRLVEEQDGGILVVEKVETSTSTQNAKQKMNELFLDVEVEFVQSFYNKKPEEEPFEQFVKRICLDDKLFTVAEEIGARLNVDPKKVLIWTRVSGSRFEPFFDDYMLNTCKGLMTRPVHDPRAYKRYRVQYAIMPFDIDEISKHRIQTKLFWQLPNGHVEELTLFPLKEGTVIDIINEAKRYYPFVEGGSGKFRLLQIGAPPLSNQRVYQIYGENTLISDLDQRTMYKLVSSQALHCRLEEVPIDELDMSPGEFLCPVVHFDREPTKLFGLSFVIKIRNNELMTEVRDRLRRKLNDVSDADFAKYKFALLSRDKLQLCRTIEFNNGEKVNLADMANQTTGVPQVYIGLDHKSPIQHSSEAAIRILN
What is the function of this protein?
Hydrolase that deubiquitinates target proteins.  May play a role in regulating the levels of endogenous siRNA biogenesis (PubMed:32338603).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 7, Deubiquitinating enzyme 7, Ubiquitin thioesterase 7, Ubiquitin-specific-processing protease 7.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to the nucleus of germ cells.
Protein: ACTL7_HYDVU
Sequence: MLLYVCLVNLLLPLSDGAVNPELVGVLVKVGVDAALQQIDEVWKGSTVRDWKCAVENKSNKTLYAMGTTPESGSMTTILDDIPPENTGIFVWEKSRGAATGAAGVVHYKYGNKVLNLMASIPYDWNLYSAWANARLSDDKVSFSDLYYGQNGAKSATKGGNWGEVDGTKFFLTSKSHAEFKVIFSGK
What is the function of this protein?
Pore-forming protein that forms hydrophilic pores and causes cytolysis (PubMed:31513812).  Compared to equinatoxin-2 (AC P61914), it reveals lower cytolysis activity (5-12-fold difference, tested on erythrocytes), a larger pore size (probably 2-3 nm) and different affinity to membrane lipids (100-fold lower affinity to sphingomyelin) (By similarity).  Binds to sulfatides (PubMed:31513812).  Shows cytolytic activity on HeLa cells, with a different potency than its paralogs (from most potent to less potent: HALT-4>HALT-6~HALT-1>HALT-3>HALT-7>HALT-2) (PubMed:31513812).  Pore formation is a multi-step process that involves specific recognition of membrane lipid by a protein aromatic residues rich region, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers (By similarity).  In vitro, binds to the folate receptor alpha (FOLR1), a GPI-anchored membrane protein that plays a major role in the uptake of folate/folic acid into cells via endocytosis, suggesting a possible involvement of this receptor in the mechanism of HALT-1-induced cell lysis (By similarity).  In vivo, does not cause visible paralysis in larvae of the blowfly Sarcophaga faculata, the most common arthropod prey of Hydra (By similarity).
What are the official names of this protein?
Hydra actinoporin-like toxin 7, HALT-7, Alpha-pore-forming toxin, alpha-PFT, DELTA-hydritoxin-Hma1g, DELTA-HYTX-Hma1g.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. HALT subfamily.
Protein: YQGF_MYCPU
Sequence: MAKVMRKIALDLGTKSCGFAISDPISNSFAIPLENFFFEENNFKKVINKLKHYEKKYEFDTIILGYPLRMTGTRSERSIMVEEFEKLLRKTFSQRIVLVDERLSTVKAKAMLKETNISQSKIKEKKDSMAAALLLNYYLNNFLGVR
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TVBK3_HUMAN
Sequence: MGTRLLCWVAFCLLVEELIEAGVVQSPRYKIIEKKQPVAFWCNPISGHNTLYWYLQNLGQGPELLIRYENEEAVDDSQLPKDRFSAERLKGVDSTLKIQPAELGDSAVYLCASSL
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 11-3.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PSTB_LEIXX
Sequence: MSKRIEVNDLNVYYGKFHAVEDVSLTIEPRSVTAFIGPSGCGKSTFLRTLNRMHEVIPGAYVEGEVLIDGNNLYGAGVDPVLVRRQVGMVFQRPNPFPTMSIRDNVLAGVKLNNHRISKTDADDLVEGSLRGANLWNEVKDRLNLPGSGLSGGQQQRLCIARAIAVSPDVLLMDEPCSALDPISTLAIEDLIEELKNDYTIVIVTHNMQQASRVSDRTAFFTIAGTGKPGKLIEYNDTNIIFSNPSAQATEDYVSGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL29_CLOPS
Sequence: MKARELKELRTSNPQDLIKKLGDLKAELFNLRFQLATGQLENPMRIREVKKSIAQIKTIIREEELKIEQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: NDUA4_PANTR
Sequence: MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNNPEPWNKLGPNDQYKFYSVNVDYSKLKKERPDF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.  NDUFA4 is required for complex IV maintenance.
What are the official names of this protein?
Cytochrome c oxidase subunit NDUFA4.
What is the protein family that this protein belongs to?
Belongs to the complex IV NDUFA4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PTKC_ECO57
Sequence: MFSEVMRYILDLGPTVMLPIVIIIFSKILGMKAGDCFKAGLHIGIGFVGIGLVIGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPIAILVNVAMLLTRMTRVVNVDIWNIWHMTFTGALLHLATGSWMIGMAGVVIHAAFVYKLGDWFARDTRNFFELEGIAIPHGTSAYMGPIAVLVDAIIEKIPGVNRIKFSADDIQRKFGPFGEPVTVGFVMGLIIGILAGYDVKGVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAKQARSRLQAKFGGQEFLIGLDPALLLGHTAVVSASLIFIPLTILIAVCVPGNQVLPFGDLATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQTIGLHTQLAANAGALKAGGMVASMDQGGSPITWLLIQVFSPQNIPGFIIIGAIYLTGIFMTWRRARGFIKQEKVVLAE
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.  The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport.
What are the official names of this protein?
PTS system galactitol-specific EIIC component, EIIC-Gat, Galactitol permease IIC component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NQRA_TERTT
Sequence: MIKIRRGLDLPITGEPRQSIEDGPSIRSVAVIGFDYHGMKPTMAVQEGDKVKKGQLLFTDKKTEGVRYTAPASGTVSAVNRGYQRVLQSVVIDVEGGEAETFAKYSESDLANLARQQVVDNLNDAGLWAAIRTRPFSKAPALDAVPAAIFVSAMDTNPLAADPTLIINERPQSFINGLVVLSKLTEGKLFVCHAEGASVPQSSVATYETFGGVHPAGNVGTHMHFLAPVSLERQSWSVGYQDVMAIGDLFTSGELASERVVALGGPQMENPRLVRTLVGASLEELTAGQLKAGENRMISGSVFGGRNAYGPTAFLGRYHNQVSVLAEGRERPFMHFVVPGSKRFSALPIYISTLMKGKKYDFTTSCNGSERAMVPTGSYEQVMPLDILATQLLRSLIVGDTEMAQKLGCLELDEEDLALCSFVCSGKYEYGPILRDNLTRIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: DDL_MARMS
Sequence: MSKTLKESVIAVIYGGRSAEREVSLQSGPLVAEGLRAKGYQVVELDLYGSNAALDPIVQLQSIEFDLAFIALHGGEGEDGRVQALLEMFGKPYTGSSPLACGLAMDKVLTKRFWNGIGIPTPAYLSFVDHANADLIEEQMSYPVIVKPSREGSTIGINKAMNRAELDDALIKALEYDSDILVEEFIDGPEFTVTVIDDVAYPPIGLKPAPDHKLYDYEAKYIADDTEYLLPCGLDEDDENELQMLALDAYRSLGCFGWGRVDVMRDQAGVFWVLEVNTAPGMTSHSLVPMAAKYVGIDYASLVEKIAQNAWDKVGRN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_PAPCY
Sequence: VHLTPEEKNAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSPAAVMGNPKVKAHGKKVLGAFSDGLNHLDNLKGTFAQLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RF1_SYNC1
Sequence: MIFNKLEEVEDRFREVEGLLSDPQVVSQQKRFLELTREHAELSSVVAVYREYKRVSEDIEGNRELLQDSDPEMREMAKAELPELEAHREELAQQLKVLLLPKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRFAEGQGWKVETMSVSDSEAGGFKEIIAMISGNRVYSQLKYESGTHRVQRVPETEAQGRIHTSACTVAVLPEAEDVDVDIDPTDLRIDVYRASGAGGQHVNKTESAVRITHVPTGVVVSCQDEKSQHKNKAKAMKVLKSRILDQVMADQQAQMAADRKSQVGSGDRSQRIRTYNFPQGRCTDHRIGLTLYRLEGIMQGNLSELVEPLTLHYQSEAMAAQEA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP7Q_YEAST
Sequence: MLKSGRLNFLKLNINSRLLYSTNPQLTKKVIGIDLGTTNSAVAYIRDSNDKKSATIIENDEGQRTTPSIVAFDVKSSPQNKDQMKTLVGMAAKRQNAINSENTFFATKRLIGRAFNDKEVQRDMAVMPYKIVKCESNGQAYLSTSNGLIQSPSQIASILLKYLKQTSEEYLGEKVNLAVITVPAYFNDSQRQATKDAGKLAGLNVLRVINEPTAAALSFGIDDKRNNGLIAVYDLGGGTFDISILDIEDGVFEVRATNGDTHLGGEDFDNVIVNYIIDTFIHENPEITREEITKNRETMQRLKDVSERAKIDLSHVKKTFIELPFVYKSKHLRVPMTEEELDNMTLSLINRTIPPVKQALKDADIEPEDIDEVILVGGMTRMPKIRSVVKDLFGKSPNSSVNPDETVALGAAIQGGILSGEIKNVLLLDVTPLTLGIETFGGAFSPLIPRNTTVPVKKTEIFSTGVDGQAGVDIKVFQGERGLVRNNKLIGDLKLTGITPLPKGIPQIYVTFDIDADGIINVSAAEKSSGKQQSITVIPNSGLSEEEIAKLIEEANANRAQDNLIRQRLELISKADIMISDTENLFKRYEKLISSEKEYSNIVEDIKALRQAIKNFKANENDMSIDVNGIKKATDALQGRALKLFQSATKNQQNQGK
What is the function of this protein?
Required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria (PubMed:10779357, PubMed:11273703, PubMed:12756240, PubMed:15123690, PubMed:15958384, PubMed:16431909, PubMed:9660806, PubMed:31040179).  Assisted by the DnaJ-like co-chaperone JAC1 and the nucleotide exchange factor MGE1, it mediates ATP-dependent Fe-S cluster transfer from the scaffold proteins ISU1/ISU2 to GRX5 (PubMed:11273703, PubMed:12756240, PubMed:15123690, PubMed:15958384, PubMed:16431909, PubMed:31040179, PubMed:26545917, PubMed:23615440).
What are the official names of this protein?
Iron-sulfur cluster biogenesis chaperone, mitochondrial, Heat shock protein SSQ1, mitochondrial, Stress-seventy subfamily Q protein 1, mtHSP70 homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CHCB3_ANTPO
Sequence: DGIFPTVGAGDVWYGCGDGAVGIVAETPFASTTTNPA
What is the function of this protein?
This protein is one of many from the eggshell of the silk moth.
What are the official names of this protein?
Chorion class CB protein PCH12.
What is the protein family that this protein belongs to?
Belongs to the chorion protein family.
Protein: FUS_MEASF
Sequence: MGLKVNVSAIFMAVLLTLQTPTGQIHWGNLSKIGVVGIGSASYKVMTRSSHQSLVIKLMPNITLLNNCTRVEIAEYRRLLRTVLEPIRDALNAMTQNIRPVQSVASSRRHKRFAGVVLAGAALGVATAAQITAGIALHQSMLNSQAIDNLRASLETTNQAIEAIRQAGQEMILAVQGVQDYINNELIPSMNQLSCDLIGQKLGLKLLRYYTEILSLFGPSLRDPISAEISIQALSYALGGDINKVLEKLGYSGGDLLGILESRGIKARITHVDTESYFIVLSIAYPTLSEIKGVIVHRLEGVSYNIGSQEWYTTVPKYVATQGYLISNFDESSCTFMPEGTVCSQNALYPMSPLLQECLRGSTKSCARTLVSGSFGNRFILSQGNLIANCASILCKCYTTGTIINQDPDKILTYIAADHCPVVEVNGVTIQVGSRRYPDAVYLHRIDLGPPISLERLDVGTNLGNAIAKLEDAKELLESSDQILRSMKGLSSTSIVYILIAVCLGGLIGIPALICCCRGRCNKKGEQVGMSRPGLKPDLTGTSKSYVRSL
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with H at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: Y877_RICBR
Sequence: MLKKIIILFLGVFVLSGCTDSFRGYFQKSANNRLVDSKGFKGGKRKPLYNNKYISLAKKNIVEDNLDDPEDDDDDYDNPLRGEQIDPVKRNREIYLKMIRRDMEKYKAESGESSDDDDMTLSKANKKVRKDNTDKERKMQEELDQIKAMLRETKRDISKYTCPNATANQNYVPPVSNYEPVAPVKNNKPYNNNSKVKQKFIREDDDYSSNACSI
What are the official names of this protein?
Uncharacterized lipoprotein RBE_0877.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ROT1_YEAS7
Sequence: MWSKKFTLKKLILGGYLFAQKVYCEDESNSIYGTWSSKSNQVFTGPGFYDPVDELLIEPSLPGLSYSFTEDGWYEEATYQVSGNPRNPTCPMASLIYQHGTYNISENGTLVLNPIEVDGRQLFSDPCNDDGVSTYSRYNQTETFKEYAVGIDPYHGIYTLQLYQYDGTPMQPLYLAYRPPMMLPTETLNPTSSATSTDDSSSNKKRSLRSLVRRSLENRHKTNAIKRQNTSFLTSNAIWYISAGMLGVGSLLFLAF
What is the function of this protein?
Required for normal levels of the cell wall 1,6-beta-glucan.  Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies.  Controls actin cytoskeleton polarization to the mother-bud neck and CLB2 protein stability (By similarity).
What are the official names of this protein?
Protein ROT1, Reversal of TOR2 lethality protein 1.
What is the protein family that this protein belongs to?
Belongs to the ROT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: LEPA_MYCTA
Sequence: MRTPCSQHRRDRPSAIGSQLPDADTLDTRQPPLQEIPISSFADKTFTAPAQIRNFCIIAHIDHGKSTLADRMLQLTGVVDERSMRAQYLDRMDIERERGITIKAQNVRLPWRVDKTDYVLHLIDTPGHVDFTYEVSRALEACEGAVLLVDAAQGIEAQTLANLYLALDRDLHIIPVLNKIDLPAADPDRYAAEMAHIIGCEPAEVLRVSGKTGEGVSDLLDEVVRQVPPPQGDAEAPTRAMIFDSVYDIYRGVVTYVRVVDGKISPRERIMMMSTGATHELLEVGIVSPEPKPCEGLGVGEVGYLITGVKDVRQSKVGDTVTSLSRARGAAAEALTGYREPKPMVYSGLYPVDGSDYPNLRDALDKLQLNDAALTYEPETSVALGFGFRCGFLGLLHMEITRERLEREFGLDLISTSPNVVYRVHKDDGTEIRVTNPSDWPEGKIRTVYEPVVKTTIIAPSEFIGTIMELCQSRRGELGGMDYLSPERVELRYTMPLGEIIFDFFDALKSRTRGYASLDYEEAGEQEAALVKVDILLQGEAVDAFSAIVHKDTAYAYGNKMTTKLKELIPRQQFEVPVQAAIGSKIIARENIRAIRKDVLSKCYGGDITRKRKLLEKQKEGKKRMKTIGRVEVPQEAFVAALSTDAAGDKGKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACCD_AGRRK
Sequence: MNWITNYVRPRINSMLGRREVPENLWIKCPETGEMVFHKDLEDNKWVIPASGFHMKMPAKARLADLFDKGEYEALQQPKVAQDPLKFRDSKKYTDRLKDSRVKTDQEDTIVAGVGKVRGLKLVAVVHEFNFMGGSLGIAAGEAIVKAFERAIAEKCPLVMFPASGGARMQEGILSLMQLPRTTVAVDMLKEAGQPYIVVLTNPTTGGVTASYAMLGDVHLAEPGAEICFAGKRVIEQTIREKLPEGFQTSEYLLEHGMVDMVVKRHDIPDTLATLLKILTKAPANDVSAKSLNGAAAPLVANG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTMRA_MOUSE
Sequence: MFSLKPPRPSFRSYLLPPAQTDDKISSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKVNGVSSGGGGVWSGAGSTGSQRTPLFETYSDWDRETKRTGASGWRVCSINEGYMISTCLPEYFVVPSSLADQDLKIFSHSFVGRRMPFWCWSHSNGSALVRMALIKDALQQRKIDQRICNAITKSHPQRSDVYKSDLDKALPNIQEIQAAFVKLKQLCVNEPFEETEEKWLSSLESTRWLEYVRAFLKHSAELVYILESQRLSVVLQEEEGRDLSCLVASLIQVMMDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKESPLFLLFLDTTWQLLEQYPAAFEFSETYLAVLCDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGDEKGLKFPSVWDWALQFTAKDRTLFHNPFYIGKSTPCVQNGSRKSFKRTKKSYSSTLRGMPSCLKNGIITDQDLLPRRNSLVLKLKPDPPQHTDSQHSGAEQYFKEWFSRPANLHGIILPRLSGTHIKLWKLCYFRWVPEAQINLGGSIMAFHKLSLLADEVDMLSRMLRQHRSGPLEACYAELDQSRMYFRATGPHDTLGTPEFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED
What are the official names of this protein?
Myotubularin-related protein 10, Inactive phosphatidylinositol 3-phosphatase 10.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.