PharMolix/UniProtQA huggingface dataset:
Protein: MMPLA_STRCO
Sequence: MTRTLLSWPGGRRLKWLVLAAWIGLLIVLQPLAGKLGDVESNDAAAWLPGNAESTEVLELSEKFQPADTSPTVIVYDRPSGITAADEAKARADATHFADGTGVVGEPYGPVRSDDGKALRTVVNVHLGKDGWEGLNAAAKDMRAIARPSAPDGLGVHVTGPTGYAADSAESFSSADFKLTLVTLLIVVTILVVTYRSPLLWLLPMISAGMSLVISQAIVYLLAKNAGLTVNAQTAMILTVLVLGAATDYALLLVARYREELRRHEDRHEAMAVALRRAGPAIVASAATVAVSMLVLLLAALNSTKGLGPVCAVGVLVGLLSMMTLLPALLVIFGRWVFWPARPKHGTEPDVTRGLWSRIARLVSGRPRAVWVTTSLLLGAVATLAVTLNADGLQQKDGFKTKPESVVGEEILTRHFPAGSGEPMVVIAKGASADQVHAALETVPGVIEVAPPQVKDGLAYVEATLGAGADSPAAMRSVTAARETLARLDGAQARVGGSSAVVHDMREASSRDRGLIIPVILAVVFCILALLLRALVAPLLLIASVVLSFFTALGLAALFFNHVFDFAGADSAFPLWVFVFLVALGVDYNIFLVTRIKEESDRLGTRQGALKGLTSTGGVITAAGLVLAGTFAALATLPLVFIAELGFTVAVGVLLDTMIVRSVLVTALTLDVGRWMWWPHPLARREDPSEDPAVSGMPDSIDSEASTTASR
What are the official names of this protein?
Putative membrane protein ActII-3.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THII_HAES1
Sequence: MKFIIKLFPEIMIKSESVRKRFVKILTGNIRNVLNKYDDTVAVVKHWDYIEVRSKNIENRILLVELLGRIPGIHHFLEVEEKPFVTLHDIFEQTLSDVATQIENKTFCVRVKRKGKHDFSSLDAERYIGGGLNQAVASAKVQLSKPDVTVRIDIENDKMMLIKARHQGIGGYPIGTQEDVLSLISGGFDSGVSSYMLIRRGSRVHYCFFNLGGATHEIGVKQMAYHIWKRFSGSHKVRFVAINFEQVVAEILEKVDNGQMGVVLKRMMVRAASKVAQRFGIQAIVTGEALGQVSSQTLTNLRLIDEAAESLVLRPLITHDKEQIIAKAKEIGTEDIAKSMPEFCGVISKSPTVKAVKEKIEQEESYFDFSVLESAVQNAQYLDIRQIAEQTKKEVFEVDEITVLSANDVILDIRSPEEVDDKPLEISGQNIILMPFYKLSSHFAELDQSKNYVLYCERGVMSKLQALYLREKGFDNVKVLNKIS
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1AT2_MOUSE
Sequence: MTPSISWGLLLLAGLCCMVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIVEAVKELDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDKSTTVKVPMMMLSGMLDVHHCSILSSWVLLMDYAGNASAVFLLPEDGKMQHLEQTLNKELISKILLNRRRRLVQIHIPRLSISGDYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSKAVHKAVLTIDETGTEAAAATVFEAVPMSMPPILRFDHPFLFIIFEEHTQSPIFVGKVVDPTHK
What is the function of this protein?
Inhibitor of serine proteases.  Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.
What are the official names of this protein?
Alpha-1-antitrypsin 1-2, AAT, Alpha-1 protease inhibitor 2, Alpha-1-antiproteinase, Serine protease inhibitor 1-2, Serine protease inhibitor A1b, Serpin A1b.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: KIZ_HUMAN
Sequence: MSRTLASAVPLSSPDYYERLGQLQHGLRDSEKKRLDLEKKLYEYNQSDTCRVKLKYVKLKNYLKEICESEKKAHTRNQEYLKRFERVQAHVVHFTTNTEKLQKLKLEYETQIKKMLCSKDSLGLKEELTDEDREKVAVHEGINSGTAMSRGLYQPATIFMGRQMSAILSMRDFSTEHKSPQPTKNFSIPDPHSHRQTAQSSNVTDSCVVQTSNDTQCLNKSDNIDGKASLQIGEKMPVTASVLSEEEQTHCLEIGSNTRHGKSNLSEGKKSAELNSPLRERLSPENRTTDLKCDSSSGSEGEILTREHIEVEEKRASPPVSPIPVSEYCESENKWSQEKHSPWEGVSDHLAHREPKSQKPFRKMQEEEEESWSTSSDLTISISEDDLILESPEPQPNPGGKMEGEDGIEALKLIHAEQERVALSTEKNCILQTLSSPDSEKESSTNAPTREPGQTPDSDVPRAQVGQHVATLKEHDNSVKEEATALLRKALTEECGRRSAIHSSESSCSLPSILNDNSGIKEAKPAVWLNSVPTREQEVSSGCGDKSKKENVAADIPITETEAYQLLKKATLQDNTNQTENRFQKTDASVSHLSGLNIGSGAFETKTANKIASEASFSSSEGSPLSRHENKKKPVINLKSNALWDESDDSNSEIEAALRPRNHNTDDSDDFYD
What is the function of this protein?
Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation.  Required for stabilizing the expanded pericentriolar material around the centriole.
What are the official names of this protein?
Centrosomal protein kizuna, Polo-like kinase 1 substrate 1.
What is the protein family that this protein belongs to?
Belongs to the kizuna family.
Protein: PSAC_SACHY
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGPETTRSMALSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RL6_METM6
Sequence: MPVAALIREEIEIPANVNVEINGNTVAVKSGAKELKRDLLYPGIEISTEDGKVVIECTFPRKAQTAIVGTYRSHIQNMIKGVTDGFEYKLVIRYAHFPMKVSAKGNTVMIDNFLGEKYTRTAKIMDGVTVKVSGEEVIVSGANKEFVGQTAANIEQATKVKGRDTRIFQDGIYIVEKAGKVL
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DLT1_YEAS8
Sequence: MSGFAKLKSWLYKASLFVSLILLIGFSVVLPIDSIAQASKSENNAFNTFIVVGALVVFGVFCIFIIIGRMLFHKSCLKDIPRRYIPITPADLPHRSSREAVLQNMERSKELTILLKKPKDPVIHDGLEPPRRCDYPLDEKLFPEYLNYADCIKSLTDRLKYHGLFLNNLDVRMNLEDTFADVVNSQFVNHNANKIQLEKAKEFIDLYETIRFSGKDVTRDQFIKFVKFCLYFGEVSLTRDTSFANLHNFRLNGSSNNIGRTESKYSINPFDENEYAQDDMHYFPEPPTHLVRESSISTVARHVSSGVDLTNSEEHPLDTDSDCNALRLKLSKADSYRSVIRH
What is the function of this protein?
Required for growth under high-pressure and low-temperature conditions.
What are the official names of this protein?
Defect at low temperature protein 1.
What is the protein family that this protein belongs to?
Belongs to the DLT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RIBBA_NOCFA
Sequence: MTRFDTIERAVADIAAGKAVVVVDDEDRENEGDLIFAAEKATPELVAFMIRYTSGYICVPLTGEDCDRLGLPPMYATNQDKHGTAYTVSVDAREGITTGISAADRATTMRLLADADAKADDLTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLRPAGVICEIVSQKDEGHMARTEELRVFADDHDLALISIADMIAWRRKHEKQVVRVAEARIPTAHGAFTAVGYQSIYDDVEHVALVRGDIGDGEDVLVRVHSECLTGDVFGSLRCDCGPQLDAALEMVDQEGRGVVLYMRGHEGRGIGLMHKLQAYQLQDSGRDTVDANLDLGLPADARDYGTGAQILVDLGIRSMRLLTNNPAKRVGLDGYGLTITERVPMPLRANAENLRYLRTKRDRMGHDLVGLDDLDLGETAQ
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: CYNS_ECO5E
Sequence: MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARQVGAKLDLDEDAILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: AZOR_GEOSE
Sequence: MTNVLYITAHPHDDTQSYSMAVGKAFIDTYKQVHPDHEVIHLDLYKEYIPEIDVDVFSGWGKLRSGKSFEELSDEEKAKVGRMNELCEQFISADKYVFVTPMWNFSFPPVLKAYIDAVAVAGKTFKYTEQGPVGLLTDKKALHIQARGGFYSEGPAAEMEMGHRYLSVIMQFFGVPSFEGLFVEGHAAVPEKAEEIKANAIARAKDLAHTF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: NEDD8_RAT
Sequence: MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGGLGQ
What is the function of this protein?
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53.  Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.  Attachment of NEDD8 to p53/TP53 inhibits p53/TP53 transcriptional activity.  Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M.
What are the official names of this protein?
NEDD8, Neddylin, Ubiquitin-like protein NEDD8.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Nucleus. Note=Mainly nuclear.
Protein: RL3_ACISJ
Sequence: MSLSNSLGLLGRKVGMMRLFTDDGDAVPVTVVDVSNNRVTQVKTQENDGYVSLQVTFGSRKASRVTKPEAGHLAKAGVEAGEIIREFRVTPEVAGKYAAGAAVPVADVFAVGQKVDVQGTSIGKGFAGTIKRHNFGSQRASHGNSRSHNVPGSIGMAQDPGRVFPGKKMTGHLGDVTVTTQNLDVVRIDEARQLLLIKGAVPGSKGGFVTVRPAVKAQASKGAN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CCSA_GUIAB
Sequence: MIFSTLEHILTHISFSIVSIVITLHLITLLGNEIIKPYDSSEKGMIATFLCLTGLLITRWIYSGHFPLSDLYESFIFLSWSFSLIHIVPYFKIRKNDLTTITASSTIFTQGFATSGLLNEIHKPTILVPALQSEWLIMHVSMMILSYAALLCGSLLSVALLVITFRNIFYSSKSNNFLKLNESFSFGEIQYKNERNNIFQKTYFFSDKNYYKAQFIQQLDYWSYRVISLGFIFLTIGILSGAVWANEAWGSYWSWDPKETWAFITWIVFAIYLHTRTKKNLQGANSAIVATLGFLIIWICYFGVNLLGIGLHSYGSFTLTSS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HISX2_TRIV2
Sequence: MLRIITQQADVKAELQRICDRTHDEQVLHKEATVREVLQAVKRQGDKAVLHYTDEFDNQILKAEELRVTGSELDAAYQQVSKELLEAIQLASRQIEAFHRQRVPKSWVHFGDDDIVLGKRYTPVDRAGLYVPGGRAAYVSTVLMNAIPAKVAGVPRIVMATPPGAQKAINPAVLVAAQEVGVQEIYRVGGAQAIAALAYGTETIPKVDVITGPGNIYVTLAKKLVYGTVGIDSLAGPSEVLIIADEGANPVHVATDMLAQAEHDPMAAAILFTTDPALAKNVQVAVERQLVDHPRRIDTEKAIAHYGLIVLVESLDAAAELSNEFAPEHLELEVKDPWAVLPNIRHAGAIFLGYSTPEAVGDYLAGPNHTLPTSGAARYASALSVETFLKHSSIIQYSQTALNKVAGAIDALATAEGLPSHADSVKRRIQQDE
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase 2, HDH 2.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: TO6BL_MOUSE
Sequence: MERTALAVCEILRYLIIHWKCEAGTAKGTLLDGQLVISIEALRSKHLPDSLHCIITIASTRSVYGGLNFKKFLQEIQPALPRLSAKLALASEEGGRSQDASGIAPCQVTFEVDENSQSLMTDCLVIKHFLRKIIIVHHKLKFSFSVAVNGTLSAETFGAENEPTLRLDNGVTLVVGFQRYVSKPKLNWSEAHCSRIHPVLGHPAPLFIPDAKADTGLLGELTLTPAAALCPSPKGFSSQLCRISSVSIFLYGPLGLPLLSSDQDQPSTAVFRDTSYFIDWKKYNLFMVPNLDLNLDTQSVLPDVNYKAESPEGNQSQNMNAQGPALLLFLFVDFQSDVPVQQAKIWGLHTLLTAHLSAILSESRSTVQQSIQSAVDQVWQLYHHDAKTQQRLQASLSVAVNSIMSVLTGSTRSSFRKTCLQALEAADTQEFGVKLHRIFYDITQHQFLKHCSCDTEQHLTPEKNISAQNTKDQHKNIAQEFPEESIGQAENKRPKRGSPNHGREESRVLGSARDRSPPKSATRDRELTEVSLTARGSQTQAAHGRAQAAEAASPAGGLEDLWLQEVSNLSEWLNPGHRS
What is the function of this protein?
Component of a topoisomerase 6 complex specifically required for meiotic recombination.  Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.  The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B-like, Type 2 DNA topoisomerase VI subunit B-like, TOPOVIBL.
What is the protein family that this protein belongs to?
Belongs to the TOP6B-like family.
What are the subcellular locations of this protein?
Chromosome. Note=Localizes to meiotic chromosomes.
Protein: DNAA_CLOK1
Sequence: MNAHPKEIWEQCLNIIKGETTEVSFNTWIKSITPISIENDTFMLTVPNDLTKGILSNKYTDLIIRSLQMVTSQKYNVKFLISSELPEEFLTLDTINEQNIKGSIIVSDEMSAMLNPKYTFTSFVIGNSNRFAHAASLAVAESPAKAYNPLFIYGGVGLGKTHLMHAIGHHILHNNTSCKVVYVSSEKFTNELINSIKDDKNVEFRSKYRNIDVLLIDDIQFIAGKERTQEEFFHTFNALYEANKQIILSSDRPPKEIPTLEDRLRSRFEWGLIADIQPPDFETRMAILKKKADVEKLNIPNEVMAYIATKIKSNIRELEGALIRIVAFSSLTNKEISVDLAIEALKDIISSGQSKQVTIELIQDVVSNYYNLKVSDFKSSRRTRNVAFPRQIAMYLCRKLTDMSLPKIGEEFGGRDHTTVIHAYEKISNNLKKDESLKNAVNDLTKRLDQQ
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYRC_SCHPO
Sequence: MATSVDQISKSLSTLGLQDLPVFREADIHHNPVDVYRSYISSELSKINGVDVSLIYPALETSISKDSADLNLPVPRLRVKGKPQELAQKWAEAFPKDLVEVTANGIFLRFNFNGPSLTKLILPIIWEQRENYGRNESGSGKVAVIEFSSPNIAKPFHAGHLRSTIIGSFLANLHESQGWKVHRVNYLGDWGKQFGLLAIGYKKYGDEDQLKSNPIRHLYDVYVKVNADATEEDEKIQKDKAEAESKGLPYTPPLSLHDKAREFFKRMEDGDEESLKVWARFRDLSITKLKDTYDRLNIHYDEYDGESQVSLELMNKMVDELRSLNLIEEDGGALLIDLSKHDKKLGKAIVQKRDGTTLYLTRDIGTAYKRYEKYKFDKSIYVVSSQQDMYFSQLFKIFELMGFDWAKKCVHINYGLVQGMSTRKGKAVFLDDIMEVAKEEMHKVMQKNEEKYAQVENPEEVADIVGKTAIRIQDSTGKRINNYAFDWSRMTSFEGDTGPYLQYAHSRLSSVRRNVNYTDEEIMGANLELLTEPDAYDLVRLLGQYPDVLKNAFRFQETSTVVTYLFKLTHAVSKLYDILWVRGRERDIQLARLALFGAAKQVLNNGMTLLGLTPLERM
What is the function of this protein?
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.
What are the official names of this protein?
Probable arginine--tRNA ligase, cytoplasmic, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUB_BACHK
Sequence: MTVSINEVSKYFSKQTGTVQVLENINFQLEKGDFVTVIGPSGCGKSTLLKIVAGLDNDFEGEIIIDGERITKPSKKQGFIFQEHRLFPWLTVEENIAADLSLKDKYVKDKVKEWVEIVRLDGFEKSYPKEISGGMSQRVAIARALLRDPSVLLLDEPFGALDAFTRSHLQEVLLNIWEQKKTTMIFVTHDIDEAIYLSNRIVIMSAKPGEIHKVIENNLSYPRNKTSQSFQQLRTKVLQQFEHGGLIQTSI
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNLJ_STRPN
Sequence: MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELETAYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSCEELDAFDARVRKEVAHPTYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDITVRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQEASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVVIKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIPTNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFAANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGSKVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETGVNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVVVGADAGSKLQKAQELGIQVRDEAWLESL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CDC11_ENCCU
Sequence: MIVRRQNRRFTIMAAGPRGSGKSSFFNSLIGKEIVTSRGHEGIDLYMLNLDCEGIMQRITLIDTPGFGEGFDDSEIQETICNFIKAQLDMFIAEESKIRRNPKYEDTRVHCLLYFIPSTSSSLKSRDIAFLRKVSGLVNIIPVISKSDGLSITERIEVKRQVMEQIKHYNISIFDLDDPEVYSSPAAGNDLNSLVPFLVVSADRENFESRARNYQWGDVSIDNPDHCDLPALRELLLSTHIYGLIDYTASEIYENYRAAVLEGGVRK
What is the function of this protein?
Septins are GTPases involved in cytokinesis.  The septins localize to the site of cleavage and act as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle.  Septins are also involved in cell morphogenesis, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation (By similarity).
What are the official names of this protein?
Cell division control protein 11.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Protein: Y1909_ACIBT
Sequence: MFGLFIITAIAEILGCYFPYLILKEGKSAWLWLPTALSLAVFVWLLTLHPAASGRIYAAYGGIYIFTALMWLRFVDQVALTRWDILGGVIVLCGAGLIILQPQGLIR
What are the official names of this protein?
UPF0060 membrane protein A1S_1909.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EIF3D_SCHPO
Sequence: MATGFKLPELAPVKSAWGPPETEQIGGDIPYAPFSKGDRLGKIADWSVDQPKDGREQRGRQGAFAGRFRDQYQTYGYGASSIFGYQHSEDESSFSVIDRGSVNRTRTSARNGGTLLKVRGRGQNVQRGGRGGRYGSSGGRGAGDTVVSRSSGAGGARGRRFGWKDYDKHQRLRNASVTVGDDWQLLDEVEFSHLSKLNLAAAAPVTVDSYGYIYPYDKSFDKIHVKSEKPLQALDRVHYNPTTTEDPVIQKLALNSDANIFITDSILSLLMCSTRSVYPWDIVITHQSGKLFFDKREGGPFDYLTVNENAYDSPMDADNREGVNSPGALSVEATYINQNFCVQALRETEEEKYKLPHPNPFYNSKEQSEPLAAHGYIYRDVDLSLETDEKPVKLMVRTEVDGYVKNPANDVQYISIKALNEYDPKFTNVTGSVDWRSKLESQRGAVFATEMKNNSCKLARWTVEALLAGVDSMKVGFVSRSNARDAQHHGILGVVAYKPADLASQMNLSLSNGWGIVRTIADVCLKMPDGKYVLVKDPNRPILRLYSVPPNTFEEAAGPSLEASSTA
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d, Microtubule-destabilizing protein moe1.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHIC2_MOUSE
Sequence: MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLRKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
What are the official names of this protein?
Cysteine-rich hydrophobic domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the CHIC family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Golgi apparatus. Note=Associated and found in vesicular structures of Golgi complex.
Protein: PAX1_MOUSE
Sequence: MKFTLGLGSRAWRVSWERAAAAAAGPGAGGALGSGSLRVSSRRGPRLARALPLCLSGGGGARALPDCAGPSPRRSGARQLAGPRAMEQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLAQPGPYEASKQPPPQPALPYNHIYQYPYPSPVSPTGTKMGTHPGVPGSAGHVSIPRSWPSAHSVSNILGIRTFMEQTGALAGSEGAAYSPKMEDWAGVNRAAFPTSPAVNGLEKPALEADIKYTQSASSLSAVGGFLPACAYPASNQHGVYSAPAAGYLSPGPPWPPAQAPPLTPHGAGVAVHGGELAAAMTFKHREGTDRKPPSPGGKATDALGSLHGLPIPASTS
What is the function of this protein?
This protein is a transcriptional activator.  It may play a role in the formation of segmented structures of the embryo.  May play an important role in the normal development of the vertebral column.
What are the official names of this protein?
Paired box protein Pax-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: DR1_HHV6U
Sequence: MPLTVRAGHAPYRLPLSNYWWLLLGRHSLRHVHSYLRLHKGLRIPLPWPEQECLHLHPKPYKCLLRYPCITRQPHLLQGWPTKSSLCECHIHFHFFT
What are the official names of this protein?
Uncharacterized protein DR1.
Protein: EFG2_BURPS
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGNNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLKLRLKANPVPVVVPIGAEENFKGVVDLLKMKAIIWDEASQGTKFDYVDIPAELADTCQEWREKMVEAAAEASEDLMNKYLEEGDLPEADIVKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELESGEAAERQASDEEKFSSLAFKIMTDPFVGQLIFFRVYSGVVNSGDTLLNSTKGKKERLGRILQMHANQREEIKEVRAGDIAAAVGLKEATTGDTLCDPAHPIVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEATVGKPQVAYRETIRSTAKDVDGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVIPREYIPAVDKGIQDTLKSGVLAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRRANPVVLEPMMAVEVETPEDYMGNVMGDLSGRRGIVQGMEDMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPKNVADAIISAKSK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.