PharMolix/UniProtQA huggingface dataset:
Protein: CLPX_ACET2
Sequence: MSRYDEKKQLKCSFCGKTQEQVKRLVAGPGVYICDECIELCSEIIEEEFEETRADAELNDIPKPSEIKEILDQYVVGQDTAKKALAVAVYNHYKRINSDVKGSDVELQKSNIVMLGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDIERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEKIIQNRIGKKSMGFGAKIESPKKANVGEILKNILPQDLLKFGLIPEFVGRLPVIVTLHSLDREALVKILTEPKNALVKQYQKLFEMDDVILEFEKEAIEAIADKAIERNTGARGLRAILEEIMLDVMYDIPSQENVEKCIITKDTVEKMVPPTVIINENKKSVKKPINKKSRVKKESAS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: QUEA_SHEFN
Sequence: MRVADFSFDLPDELIARYPTAQRNASRLLTLSGENSELADKKFTDLFNLINPGDLMVFNNTRVIPARLFGQKSTGGKLEILVERMLDDKRILAHVRSSKSPKVDTLIDLDGGYQMKMLARHDALFELELQSDKTILEVLEDVGHMPLPPYIDRPDEDTDKERYQTVYNQTPGAVAAPTAGLHFDDAMLADLKAKGVNIAFVTLHVGAGTFQPVRVDNVLEHKMHSEWANVSQEVVDLIAQTKAAGNRVVAVGTTSVRSLESAARASGDSPLEAFSGDTDIFIYPGFQFKVVDAMVTNFHLPESTLIMLLSAFAGYEAVMKAYQHAITQKYRFFSYGDAMFVTKKAP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_CHLMU
Sequence: MEKRKDTKTTLAKASDDQNKAWYVINAEGKTLGRLSSEVAKILRGKHKVTFTPHVAMGDGVIVINAEKVRLTGAKRAQKVYHYYTGFISGMREVPFENMIARKPAYVIEHAVKGMLPKTKLGRRQMKSLRVVKGSSYAQYEAIKPIVLDA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: YPEL1_COTJA
Sequence: MVKMTKSKTFQAYLPNCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKFIIELAHMIKDNGWE
What are the official names of this protein?
Protein yippee-like 1, DGL-1, Qdgl-1.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
Protein: RK36_EMIHU
Sequence: MKVVSSIGSLKKRSKDCQVVKRRGRIYLICKSDPRLKVRQGRAKMKRK
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FIS_SHISS
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: NQOR_KLEP3
Sequence: MAKILVLYYSMYGHIETMAHAVADGANRVDGVEVVVKRVPETMQAEAFAKAGGKTQNAPVATPQELAEYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKIASVFSSTGTGGGQEQTITSTWTTLAHHGMIIVPIGYGAQELFDISQVRGGTPYGATTIAGGDGSRQPSEEELAIARYQGEHVAKLAVKVHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: 1A1D_BURMS
Sequence: MNLQKFSRYPLTFGPTPIQPLKRLSAHLGGKVELYAKRDDCNSGLAFGGNKTRKLEYLIPDALAQGCDTLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYHDAVYDRVGNIQMSRMMGADVRLVPDGFDIGFRKSWEDALADVRARGGKPYAIPAGCSDHPLGGLGFVGFAEEVRAQEAELGFQFDYVVVCSVTGSTQAGMVVGFAADGRADRVIGVDASAKPAQTREQILRIAKHTADRVELGRDITSADVVLDERFGGPEYGLPNEGTLEAIRLCAKLEGVLTDPVYEGKSMHGMIEKVRLGEFPAGSKVLYAHLGGVPALNAYSFLFRDG
What is the function of this protein?
Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.  Allows growth on ACC as a nitrogen source.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate deaminase, ACC deaminase, ACCD.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: UNG_COXB1
Sequence: MTTMAETQTWQTVLGEEKQEPYFQEILDFVKKERKAGKIIYPPQKDIFNALKLTPYEAVKVVILGQDPYHGPNQAHGLAFSVRPGVPAPPSLQNIFKELHADLGVSIPSHGFLEKWAKQGVLLLNAALTVEAGKPQSHANIGWHRFTDKVIESLNDHPEGIVFLLWGSYAQKKSQLITNLRHRILKAPHPSPLSAARGFLGCRHFSKANQLLHEMGRGEIDWALDEKVS
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCP_STAA2
Sequence: MHILVTGFAPFDNQNINPSWEAVTQLEDIIGTHTIDKLKLPTSFKKVDNIINKTLASNHYDVVLAIGQAGGRNAITPERVAINIDDARIPDNDDFQPIDQAIHLDGAPAYFSNLPVKAMTQSIINQGLPGALSNSAGTYVCNHVLYHLGYLQDKHYPHLRFGFIHVPYIPEQVIGKPDTPSMPLEKIVAGLTAAIEAISNDEDLRIALGTTE
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPC1_HYPJE
Sequence: MNEDEAIQNITKKIEREKALINAANAMRSQTNNEAVRSPLDSQMRDGRRNLQFFEEKLRDIQLRKVGQGVEGMSLGADDAGRPPPPPKDASSAAWGDQAAYGQQSQVGPPSDLAPPRHNFGAPGPGAASKARPNFTKLDLIKYDTPYLGPRIQHMLSQIQFKLNVEEQYLKGVEKMVQLYGMEGDRKSKADAAARRVESKQKILLLKQALKRYEELHVDMDSADAQDDDSINTPNLRKPLSGQLSIRVVAIKDVDHATTGRFARGPETFVAVKVEDTVMARTKVSRNDRWEAEYHNMEVDKANEIELTIYDKPGEHPMPIAMLWVRISDIVEEMRRKRIEAEMNSSGWVSADRMGSTGAPSQFPMSPTSGSFGGSPQAPGGGQGQAPGPFGDPAPQPQVVTGPIDGWFNLEPAGQIQLEFSFVKENRDKRQVDLGLGRKGAVRQRKEEVHEMFGHKFVQHQFYNIMPCALCGDFLKYSAGMQCEDCKYTCHNKCYPSVVTKCISKSNAETDPDEEKINHRIPHRFQPFSNVTANWCCHCGYILPFGKKNCRKCSECGLTSHAQCVHLVPDFCGMSMAVANQILEGIRVQKQRQQKTTSLSEKTLRSGATKSPTTAGHGSSASFSSAGAGSVPGTPSAEATEAARLMYNQTSPQRPGQPGRAPSDLSAAAAASAAMAAAQGRTGYDSGPQDPYGQGHYGAAGPAPQHHKYNPADYANVDQGFPAQPPAQQRPPQPQQQQQAPPAQMPPQQPPPQQPLPPQPGQQYQQQQPAAQKPQPQPPATAQGAAAGPPGSQRKALPSATDPGTGARIGLDHFNFLAVLGKGNFGKVMLAETKRSKRLFAIKVLKKEFIIENDEVESIKSEKRVFLIANRERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQRGQFGTKRAQFYAAEVCLALKYFHENGVIYRDLKLDNIMLTLDGHIKIADYGLCKEDMWYGSTTSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLLTREPDQRLGSGPTDAQEVMSQPFFRNINWDDIYHKRVQPPFLPQIKSATDTSNFDSEFTSVTPVLTPVQSVLSQAMQEEFRGFSYTADLD
What are the official names of this protein?
Protein kinase C-like.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Protein: LACA_STRP7
Sequence: MSIVIGADAAGLRLKEVVKNFLEKENFHLVDVTAEGQDFVDVTLAVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMITMGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: TET13_ARATH
Sequence: MARDKEDQNNENPSIVQNMSFPFNTIFLISSAIFLVTAAFWFVAVMTLHYRTDECNRFVTTPGIFISFSLLAMSLTGFYAAYFKSDCLFRIHFFIFFLWMFVVVSKAIFVIFLHKETNPRLFPGTKIYEFRYEDYSGWVSRLVIKDDEWYRTRRCLVKDNVCNRLNHKMPASEFYQMNLTPIQSGCCKPPLSCGLNYEKPNNWTVSRYYNNLEVDCKRWNNSADTLCFDCDSCKAVIIADVHNTSFSITVNIIHIIFSLCIGMTGWFAWLRILRESQK
What is the function of this protein?
May be involved in the regulation of cell differentiation.
What are the official names of this protein?
Tetraspanin-13.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PURQ_RHILO
Sequence: MKSAVVLLPGLNRDRDMIAALTKISGKPPVTVWQTDTEIPDVDLIAIPGGFSFGDYLRCGAIAARMPVMRAVAEKAAKGVTVIGVCNGFQILVEAGLLPGALMRNTSLKFVCRQIKLEITNANTMFTRRYQPGQVIRSPVAHHDGNYFADAETLARLEGEGQVVFRYAEGTNPNGSINDIAGIINEQGNVLGLMPHPENLIEAAHGGSDGRALFEGALGIAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_TERTT
Sequence: MSDENTTHFGFETVNAADKAERVAGVFHSVAAKYDLMNDVMSGGIHRLWKKFTIELSGVRPGDRVLDIAGGTGDLTAKFARLVGDEGQVVLADINDSMLKVGRDKLVDKGFLGNVQYAQADAQFLPFPDNTFDCITIAFGLRNVTDKDMALAAMNRVLKPGGRLLVLEFSKPQNSLLEKAYDLYSFNVLPMMGKLITQDADSYRYLAESIRMHPDQQTLKGMMENAGFAQCRYYNMTGGIVALHKGTKA
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: FETP_ACIF5
Sequence: MSRMVQCVKLGHEAEGLDRPPYPGALGARIYQEVSKEAWQGWLKHQTMLINEYRLSPIDPKSRTFLEKQMEAYFFGDGAQSPEGYVPPAPQDS
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: RL34_STAAM
Sequence: MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SECA2_NITMU
Sequence: MSKALLAAWRINSLAPAPYPERLDTNDNALDRFLGSSLGQARLWASHLRLKRLRSFADKVVHRSNALSALSEAELAACVDDLRVKLARQGLTEDLTIEVFSLVREVCGRKLGLRHFPVQLIGGRVILAGKLAEMQTGEGKSLTAVLPAIAVALSGLPVHVITVNEYLVRRDARFMRPVYEFFGLDVGMVVPDQDPETRRNAYGCDVTYCVNKDLVFDYLRDRIDSNRDVSDARRAVARLFRGDENSRAYLRGLFFGIVDEADSVLIDEARTPLIISSSVSDKQGVDDYRRALDFCRQLRDGLHFRIFAADKLIQLTPAGRDHITNICGNLPGVWQVARARFELIEQALAAQLLYMRDKHYIVKDEKVQIVDEYTGRVMSDRTWESGLHQMIEVKEGCALTDRRKTISRITYQRFFRRYLRLGGMTGTAAEVVGELSAIFGLDVLRIPTNRAVQRKNLGTRIFLDTASRWDAVLKSIRRVRDEGRPVLIGTRSVAASEHLSSLLKTEGIEHSVINARQDEDEATVVEQAGRVGRVTVATNMAGRGTDIKLESGVSDRGGLHVILSEFHESPRIDRQLYGRAGRQGDKGSYESIVSLEDELFVLFSGEMARRVMSNSSFSNVITGMKAKLLRGSAQRSSERYYSRIRRQTVLEDQRLAKMLAFAGRGE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RS6_MYCPN
Sequence: MQYNIILLVDGSLSLEQANQVNEKQQQTLTNVEGLQTEYLGLKELAYPIKKQLSAHYYRWKFSGDNQSTKDFKRTANINKQVLRELIINLEREYGYLASINPKKQQLALQKRAKYDEIIARENNPENPDVPVTSGLASTQPRLSRTEKAQKPKEELWDVVQKMGNFDSVQANPYRPRFKRFNAEHVNQRQNQQNNNNNRFDRNRNRQHNRFKDKQ
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: CZRA_BACSU
Sequence: MTEFRETEQSAADLDEETLFLVAQTFKALSDPTRIRILHLLSQGEHAVNGIAEKLNLLQSTVSHQLRFLKNLRLVKSRREGTSIYYSPEDEHVLDVLQQMIHHTQHD
What is the function of this protein?
Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter.  Binding of zinc causes the repressor to dissociate from the DNA.
What are the official names of this protein?
HTH-type transcriptional repressor CzrA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_LYSSC
Sequence: MTSIIFMGTPDFSAPILRMLHEEGYDIKAVVTQPDRPVGRKRILTPPPVKAAALELGLPIIQPEKLRGSEELQQILSLQPDIVITAAFGQILPKELLDAPSLGCINVHASLLPKYRGGAPIHQAIIDGEKETGVTIMYMAEKLDAGDIISQRAIPIELDDHTGRVFDKLSMVGRDLLKDTLPSIINRTNNRTVQDETQVTFASNISREQERIDWTNDATTLYNQVRGLHPWPVAYTTFEDGNFKVWWATIGKSKHDTIPGTVVAIAKDHFEVAAGNGTTLALYDVQPAGKKRMTAEEYLRGTGSKLQIGDQFK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PAR3_RAT
Sequence: MEMKVLILVGVRLLFLPTTVCQSGMKHVSDNSALTAESFNGNEHSFEEFPLSDIEGWTGATTTIKAKCPEESITTLHVNNATMGYLRSSLSTKVIPAIYILVFVIGVPANIVTLWKLSSRTKSICLVIFHTNLAIADLLFCVTLPFKIAYHLNGNDWVFGEVMCRVTTVAFYGNMYCAILILTCMGINRYLATVHPFTYRKLPKRNFTLLMCGVVWVMVVLYMLPLAILKQEYHLVQPGITTCHDVHDTCESPLPFQFYYFVSLAFFGFLIPFVVSVFCYTTLIHKLNAQDRKWLRYIKAVLLILVIFTICFAPTNIILIIHHANYYYSNTDSLYFMYLIALCLGSLNSCLDPFLYFIMSKIVDQLTS
What is the function of this protein?
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
What are the official names of this protein?
Proteinase-activated receptor 3, PAR-3, Coagulation factor II receptor-like 2, Thrombin receptor-like 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PFKA_KLEP3
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVFGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFREEHIRAVAIENMKKRGLDALVVIGGDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFIMVPEVEYTRDDLVAEIKAGIAKGKKHAIVAITEHMCDVDELASYIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIELLLQGHGGRCVGIQNEKLVHHDIIDAIENMKRPFKNDWLDCAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_LACDB
Sequence: MTKVVIENVHAREIFDSRGNPTVEVEVTLSNGVVGRAEVPSGASTGENEAVELRDGGSRLGGKGVMKAVNNVNTAINNELQGADPFNQPAIDKAMIELDGTPNKGKLGANAILGTSMATAVAAAKATHQPLYRYLGGTDLSMPQTFHNVINGGEHADNGIDIQEFMITPVKKTSFRDGFEKIVNTYHTLKKVLEEKGYETGLGDEGGFAPNMKDSEEALKALHEAIERAGYVPGEDIAIACDCAASYYYNKEDGKYHLEGKVLDGDQLAEYYDKLLAEFPELISMEDPYDENDTEGMVKFTQSHKDRLQIVLDDFICTNPRLLEKAIKEGAGNASLIKLNQIGTVTETLETIRISRKHGYNTMISHRSGETGDTFIADFAVATNGGQLKTGAPARSERVEKYNQLLRIEEQLGDGERLDFFPAQD
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: KR108_HUMAN
Sequence: MADACCTRTYVIAASTMSVCSSDVGHVSRVSSPSTCTGSSWQVDNCQESCCEPRSCASSCCTPSCCAPAPCLALVCAPVSCEPSPCQSGCTDSCTPSCCQQSSCQPACCTSSPCQQACCVPVCCKSNCCKPVCCVSICSGASSPCCQQSSCQSACCTFSPCQQACCVPICCKPICCVPVCSGASSLCCQKSSCQPACCTTSCCRPSSSVSLLCRPVCRPACCVPVPSCCVPASSCQPSCCHPASCLSFLCRPACSRLAC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 10-8, High sulfur keratin-associated protein 10.8, Keratin-associated protein 10.8, Keratin-associated protein 18-8, Keratin-associated protein 18.8.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 10 family.
Protein: SPTP_SALTY
Sequence: MLKYEERKLNNLTLSSFSKVGVSNDARLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIRVQDQKILQTFLHALTEKYGETAVNDALLMSRINMNKPLTQRLAVQITECVKAADEGFINLIKSKDNVGVRNAALVIKGGDTKVAEKNNDVGAESKQPLLDIALKGLKRTLPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQNLNKIPEAKQLNDYVTTLTNIQVGVARFSQWGTCGGEVERWVDKASTHELTQAVKKIHVIAKELKNVTAELEKIEAGAPMPQTMSGPTLGLARFAVSSIPINQQTQVKLSDGMPVPVNTLTFDGKPVALAGSYPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPPYFRGSYTFGEVHTNSQKVSSASQGEAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIHCLGGVGRTGTMAAALVLKDNPHSNLEQVRADFRDSRNNRMLEDASQFVQLKAMQAQLLMTTAS
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities.  After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE.  This function is independent of its tyrosine phosphatase activity, which remains unclear.
What are the official names of this protein?
Secreted effector protein SptP.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the YopE family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cytoplasm.
Protein: WRK63_ARATH
Sequence: MFSNIDHKAVAALLHGQGCANILKTVLDNCKVSSVSTEPLINTILDSFSLALSSVNSPNRQPHHESSSRDMAGLVPQRSSKKKICGVKGLEIYRDDSPNPRLDDGFTWRKYGQKTIKTSLYQRCYYRCAYAKDQNCYATKRVQMIQDSPPVYRTTYLGQHTCKAFGVHDNTYGSEMINFDQVVSESVMRQLATIGEQAVLMEDEANHIMNQEYDINDYLVDDEVFWGNEFPLFSSEDLMLF
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
What are the official names of this protein?
Probable WRKY transcription factor 63, WRKY DNA-binding protein 63.
What is the protein family that this protein belongs to?
Belongs to the WRKY group III family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURI_DINSH
Sequence: MAVGVFDSGLGGLTVLDAVSRRLPEVPFVYYGDNLHAPYGVRDAEDVYELTTGAVSRLWDEGCDLVILACNTASAAALRRMQESWVPSDKRVLGVFVPLIEALTERQWGDNSPPREVAIKHVALFATPATVSSRAFQRELAFRAIGVDVEAQPCGGVVDAIEDGDMILAEALVRSHVEALKRRMPHPEAAILGCTHYPLMQDVFQDALGADVKVYSQAQLVAESLADYLTRHPDMLGLGAEPGFLTTGDPKSVSNKATQFLRRKIEFRAVEPL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PIP_NEIMB
Sequence: MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRIVIIDQRGCGRSRPYACAEDNTTWDLVADIEKVREMLGIGKWLVFGGSWGSTLSLAYAQTHPERVKGLVLRGIFLCRPSETVWLNEAGGVSRIYPEQWQKFVAPIAENRRNRLIEAYHGLLFHQDEEVCLSAAKAWADWESYLIRFEPEEVDEDAYASLAIARLENHYFVNGGWLQGDRAILNNIGKIRHIPTIIVQGRYDLCTPMQSAWALSKAFPEAELRVVQAGHRAFDPPLVDALVQAVEDILPHLL
What is the function of this protein?
Specifically catalyzes the removal of N-terminal proline residues from peptides.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REGB_PSEAE
Sequence: MRLPAVTPGWPAIPPGATLGGFDGQGRRSWATISRAPSGASCSRNRSATRTYGWGATATTPATITGIPSTTAPAT
What is the function of this protein?
Required for optimal exotoxin A production.
What are the official names of this protein?
Protein RegB.
Protein: HOA_ECOLC
Sequence: MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSIEVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQAGARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGATCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLRNNK
What is the function of this protein?
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde.  Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: K1KB9_MOUSE
Sequence: MRFLILFLALSLGGIDAAPPVHSRIVGGFKCEKNSQPWHVAVYRYNEYICGGVLLDANWVLTAAHCYYEENKVSLGKNNLYEEEPSAQHRLVSKSFLHPGYNRSLHRNHIRHPEYDYSNDLMLLRLSKPADITDVVKPIALPTEEPKLGSTCLASGWGSTTPFKFQNAKDLQCVNLKLLPNEDCGKAHIEKVTDVMLCAGETDGGKDTCKGDSGGPLICDGVLQGITSWGFTPCGEPKKPGVYTKLIKFTSWIKDTMAKNL
What is the function of this protein?
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
What are the official names of this protein?
Kallikrein 1-related peptidase b9, Epidermal growth factor-binding protein type C, EGF-BP C, Glandular kallikrein K9, mGK-9, Tissue kallikrein-9.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.