PharMolix/UniProtQA huggingface dataset:
Protein: TV382_HUMAN
Sequence: MACPGFLWALVISTCLEFSMAQTVTQSQPEMSVQEAETVTLSCTYDTSESDYYLFWYKQPPSRQMILVIRQEAYKQQNATENRFSVNFQKAAKSFSLKISDSQLGDAAMYFCAYRS
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 38-2/delta variable 8.
What are the subcellular locations of this protein?
Cell membrane.
Protein: GBG12_MOUSE
Sequence: MSSKTASTNSIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLMGIPTSENPFKDKKTCIIL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RL28_STRMU
Sequence: MAKVCYFTGRKTVSANNRSHAMNKTKRVAKPNLQKVTVLIDGKPKKVWASARALKSGKVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RL27_CLOBL
Sequence: MLVMNLQLFAHKKGVGSSKNGRDSEAKRLGVKCSDGQFVLAGNILVRQRGTKIHPGLNVGRGGDDTLFAKIDGVVKYERLGRDKKKASVYPVEVEEVVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y2978_LARHH
Sequence: MLRLSRLPLPPVLQRLTGFSLFVWRRAMQNRCLQVAASLTFTTLLSLVPLITITLIVVAAFPVFEELSSQFKEFLLRNLVPDFAGRIISVYLKQFTDNAGRLTAVGLALLAFTSLSLMLTIDRTFNAIWQVQRPRKLLHNMLVYWTVLTLGPLLLGVGISGSAWILNWSGLARTAPGLAGIIQNLGSLTLATVMLTVLYGLVPNCYVPRWHALIGGALTALTLGVAQAGFGLYVEISRTYQFIYGAFATFPFLLIWLQLMWLTVLIGAELTASLSYWKGDVWRREGDSQRRFCDALDTLVRLSQAQVHGRALGQADLRHHIDTGYDEIGRILDELARLGLVQRSAEGLWALLYRPESVSLLRLWHHFVLDLNASPADDAISHSLTELVRPLEAGLDISLAEFLHRYPPAGPAVTLPAVPRPG
What are the official names of this protein?
UPF0761 membrane protein LHK_02978.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YJIE_LACLA
Sequence: MENKLNIVIITGMSGAGKTVAIQSFEDMGYFTVDNMPPNLIEKFVGLLNTPDNKIDKVALVVDMRSRAFFEDIQSIVTELTDNGSVNFKLLFLDANDTELVSRYKETRRSHPLAIDGRTLDGITKEREILADLKNLSEVVIDTSELTPRNLRARILQKFASSTESTFRIEVMSFGFKYGLPLDADLVFDVRFLPNPHYITELRDKNGTDKEVYDYVMEHPQSEEFYENLMKMLVPILPAYKKEGKSVLTIAFGCTGGQHRSVAFAERVSAALKDKWHLNVSHRDKDRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein YjiE.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: Y098_MYCPN
Sequence: MMTQGPNLIGIHTNTKENEETQKFVNWFLNTSLTWDNNESKTPAQYFTESASYILPLKETFTGSNNKGQSGKNDGKNSNNTFKAKALELFKEQSENKIVGYSDPSDFRGGKFRESIGSAFNATVNSHVDFNTFVANFRANLGSGYDK
What are the official names of this protein?
Uncharacterized lipoprotein MPN_098.
What is the protein family that this protein belongs to?
Belongs to the MG185/MG260 family.
Protein: RS5_HALSA
Sequence: MSYNDTWQPKTRLGGLVQDGEVEDMSEALDTGLPLKEPEIVDQLLPGLDDEVLDINMVQRMTDSGRRVKFRCVVAIGNRDGYVGYAEGRDDQVGGAIQKAIEVAKLNIIDVSRGCGSWECGCGRPHTVALKSTGKAGSVDVELMPAPRGLGLAGGETVQHVLELAGIDDVWTRSSGKTRTTVNFAKATFNALRETSEARVPQHAREEREVIE
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PTH_MARSD
Sequence: MEYKALIVGLGNPGSEYAKTRHNIGFMAVDALAEVAKSRKSMRFKEMGISGDFELFSLNLAGNNVLATKPLTYMNLSGKAVAAICGKYSIAVSDVYVIHDELDLPCGRMKFKKGGGNNGHRGLESIQEKMGSPNFFRIRVGIGRPEFSSQVKDYVLEEFNTQELAIAAQMSQAAIKGLNLHFRRGQGTATQFMNSFMPDLPETEP
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_FINM2
Sequence: MKILYCAAEADPFIKTGGLADVAGTLPLEMKKQGHDVKVVIPLYKLIDEEYKKKFEFEGSFYVDLDFKHHYVGVFKYIHRGVEFYFLDNEDYFNRDNVYGEYDDCERFVFFSKACVQLLRYIDFDCDIIHSNDWHTAMVNVYARDFAKGDPFYESIKTVFTIHNLKYQGVFSSNSLRQTDLSPMYFTEDALKFYDAINFMKGAIVFSDRVTTVSKTYADEIKYSFFGEGLDGVIRQYHYKISGITNGIDTTIWNPETDKYLFKNYSLKNIKDKDENKKALQRMYGLEEKNVPVFAMVTRLVENKGLELVRYIMDEFLTTEDVQVVILGTGDYSYEEMFKYYEWKFPDKLKANIYYNNEESHKIYAGADFLMMPSIFEPCGISQLIAMRYGTIPVVRETGGLRDTVQSFNEFSKEGNGFSFTNINAHDFLYTLRRAISFYYNDDFNIIKENAMNSKNDWEKSAKEYIELYEEIIK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: Y2002_RENSM
Sequence: MSGHSKWATTKHKKAVIDGRRAKSFAKLIKNIEVAARVGGPDMAGNPALELAVTKAKKTSVPNDNIDRAIKRGSGQLGEAIDYQTIMYEGYGPQGTAILIECLTDNKNRAASEVRLAVSRNGGNMADPGSVSYLFARKGIVSLPQNELSEDDLLMAVLDAGAEEVKSEGENFEVISEPQDLPAIRSALTEAGIEYDTDDAGFVPSMQVELDVENAKKFMRLYDALEDLDDVQNVYSNADVSAEVMAQLDED
What are the official names of this protein?
Probable transcriptional regulatory protein RSal33209_2002.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIA_SALCH
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQVLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_KLEP7
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNAEKVAVTGNKREDKMYYHHTGHIGGIKEATFEEMIARRPERVIEIAVKGMLPKGPLGRAMYRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PPP7L_ARATH
Sequence: MEVQSLLNFDLDPGPVDQSILVWQHEHRSAAIWEDEVPPRELTCRHKLLGMRDWPLDPLVCQKLIEFGLYGVYKVAFIQLDYALITALVERWRPETHTFHLPAGEITVTLQDVNILLGLRVDGPAVTGSTKYNWADLCEDLLGHRPGPKDLHGSHVSLAWLRENFRNLPADPDEVTLKCHTRAFVLALMSGFLYGDKSKHDVALTFLPLLRDFDEVAKLSWGSATLALLYRELCRASKRTVSTICGPLVLLQLWAWERLHVGRPGRLKDVGASYMDGIDGPLPDPLGCRWRASLSHKENPRGGLDFYRDQFDQQKDEQVIWQPYTPDLLAKIPLICVSGENIWRTVAPLICFDVVEWHRPDRVLRQFGLHQTIPAPCDNEKALHAIDKRGKSEYDWSARHSRHIGLWEARVSSVVSGEPECSPMDYNDPYMEWYRRITRRIISPMNERRPGQFLPTGFAFQVLVQRVAAIHARSRASLEEELTVGSARQTLQDIVDMCAGALQLNAPLGSLSNGSVAQAPTPEPFLMLPQPTPTIIPQKPMGGEMVCLPLNDMEIDDGLAAEPLELMPPVQDIGCEQSLSSVSQKPLFWPSGGKLTFSWVCEVMLVFDWSSKNLPPCEFSSVLPFNVLDELVLFASKILKKEPNCVRIDSEKAEVVVVGDLHGQLHDLLYLMQDAGFPDGDRFYVFNGNYVDIGAWGLETFLLLLSWKVLLPARVYLLRGSHESESCTSMYGFKNEVLTKYGDKGAAVYKKCLECFQLLPLASVIAGKVYTAHGGLFRDVSSFLSDKQERNRKRKRTQKKQTDNTVLDTEDRSESLPLGSLKDLSKVKRRVIDPPTEGSNLIPGDILWSDPSKDTGLFLNKERGIGLLWGPDCTAKFLQDNNLKWIIRGKGAPDERAKRDDLAPMNGGYAEDHEGLITLFSAPDHPQFQDTEERHNNKAAYIILQIPECEELKFQPLEAVSPRPKAEAYYDFRRLIHPPSNLVHNITNSVDSPSSVPDDKDNLISSENVEYKSMDLSEQMEVDEKDDVDSKYSESITDEVAAFGTPASGDRDMVDFSDKTENGSKEADHSETAEISKDLSDTVGKPESCSRTRGTYEAIGTDAKLKSNTPEAINLEPQPGCDLYVPDSGNSTESRTEKAAEEACVGRISIDDCSTTGDAAVELEITYDEKLDRVVTEITGNDAAECMTDGNRDIATDGAENLEPSTSKLNYSEPSEDIDDSTMKFRHNTSCVADSDLETVNGGVNADCSSSSKCLTSKPVVAHDKFTNLTKPSHDKGYGESADKPERVIKLVTYSKRKSSDKKHMIESNEDPQQKVNDSVDSKNKGSLDKSQSVPGDMDS
What is the function of this protein?
Maybe required to maintain cell division activity in meristematic cells.
What are the official names of this protein?
Serine/threonine-protein phosphatase 7 long form homolog, Protein MAIN-LIKE 3.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-7 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1854_DICDI
Sequence: MTMINSIINISLNKISKTHQINKFKNENNFYNNNLKCSDLDVDFRHQTIIGNIHLGNKGILAGIYYNI
What are the official names of this protein?
Putative uncharacterized protein DDB_G0293256.
Protein: OBLD_COCH5
Sequence: MSLGPGGFEATPNSVMPSDASLHNQSHHTDSLTNNDSIASTEQREKEVHQLARKYTQNSVYSTTSQNPFAAEPGSKLDPNGGNFSARAWAKAMLQTHTDDNQAHPLRTLGVSFSNLNVYGFGFDTDYQKSVGNIWLEAVGLVRKLMGQRERKIEILRDLEGLVEAGEMLVVLGPPGAGCSTFLKTLTGQTHGFYVDDKSNLNYQGVTPKQLIKNFRGEAIYTAEVDVHFPNITVGDTLFFAARARAPRHIPGGATIDQYAEHMRDVIMASFGISHTKNTIVGNDFIRGVSGGERKRVSISEACLSQAPLQCWDNSTRGLDSANAIEFCKTLRMQTEINGATACVAIYQAPQAAYDYFDKVLVLYKGRQIYFGPTAQAKQYFLNMGFVCPDRQTDADFLTSMTSHLERVVQPGYENQVPRTPDEFAARWKASRERAELLNQIEMYNSKYATGGEHLERFKESRRAQQAKAQRVSSPYTLSYTQQIKLCLWRSWVRLKGDPSITISSAMGNAIIALIISSMFFNLKDDTSSFFQRGSLLFFAIVINAFSSGLEMLTLYAQRPIVEKHSRFALYHPSAEAIASMLMDLPYKTLNAISSNLILYFMTNLRREPGNFFFFVFTSFVLTLTMSMFFRSIASLTRSLVEALPFAAILITGLTMYTGFTIPTSYMPGWSRWMAYIDPIAYGFESIMVNEFSGREFLCVNYVPAGPSYNVGGNNRVCSTVGSVPGQPFVLGDDYIRSTYGYEASRKWRNVGIIFAFMVILCAIYLVASDFITEKKSKGEILVFRRGHKNLDRSTGQDDVEGGSERTTTAANTKSDDIAIIEQQTAIFQWKDICYDIQIQKERRRILDHVDGWVKPGTLTALMGVSGAGKTTLLDVLASRTTMGVISGEMLVDGKERDDSFQRKTGYAQQQDLHLSTATVREALTFSALLRQPAHIPREEKIAYVTEVIKLLEMTEFADAVVGIPGEGLNVEQRKRLTIGVELAARPALLLFLDEPTSGLDSQTSWAILDLLDKLKKNGQAILCTIHQPSAMLFQRFDRLLFLKSGGQTVYYGDVGENSKILIDYFTRNGGPPCPPAANPAEWMLEVIGAAPGSHTDIDWHDTWRKSPEYAYVQAHLAELKEERSRMTDLSRTASRQAHDAASFREFAAPFWAQFYEVQLRVFQQLWRTPTYIYSKAFLCVSTSLYVGFSLYNTPNTLQGLQNQMFAIFTLFFLFGQFIQQIMPHFVAQRALYEARERPSKTYSWKAFIMSNIIVELPWNTLMSVLLFLCWYYPIGLSHNAEATDSTALRGAQMWLFVWVFLMFASTFAHFMIAALDTAENAGNMGNLLFTLCVIFCGILTTPEQMPRFWIFMYRVSPFTYLVGGMMAVGVADSSVTCAANEYLHFDPVNGTCGEYMAQYQAMAGGYVQNPSATSNCAFCPMGDTNVFLKTVHAEYSNVWRNFGLMWVFVVFNAFAACGLYYWARVPKRPTIEKEAAPIRAEGSLDSETVVGRTSAVEQQDAEKRAAF
What is the function of this protein?
ABC-type transporter; part of the gene cluster that mediates the biosynthesis of the sesterterpenes ophiobolins, fungal phytotoxins with potential anti-cancer activities (PubMed:27116000).  Acts as a specific transporter involved in ophiobolins secretion (PubMed:27116000).
What are the official names of this protein?
ABC-type transporter oblD, Ophiobolin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DDL_COPPD
Sequence: MNIVVLFGGTSPEREISLKSGENIAATLRARGHQVETLDTAVPNFVEQLMQLKPDCVFPALHGADGEDGKIQGLLSILHIPYVGSDVRASVITMDKYLTKLVALQSGIPTPSFIYVYDPHLVPDYWDVERKLGSPFIVKPCDVGSTIGLSLVRSASEYEVALEEAFRFSDRLLLEEFIDGFEVTVGLFRLGGDFLVLPPIYVVKPDRIFDYDTKYKPGGAKHVYDLPISVEARERLTSYSKRICKIVGIGGVARLDYIVKDETPYLLEINSIPGMTAESLVPDEVRHAGRDFGEFLEDLIKDAL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBZ_POPAL
Sequence: MTIAFQLAVFALIATSSILLISVPVVFSSPDGWSSNKNVVFSGTSLWIGLVFLVGILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: BICL1_XENTR
Sequence: MELPISFLSDSSRPAASSERGDQAALGRGELEFDEELVFLAAEGEGDPEEIEGPEVREQSELLCIIRQKEKDLVLAARLGKALLERNQDMSRRYEEMQREMTDKLEHLEQEKHELKRKLENREGEWEGRVSELESDVKLLQEELEKQQVNLREADREKLSVVQELSEQNQRLLEQLSRATEMERQLSQQVNVLQEEFREKSLSTSQHVSRLESLLAEIKMLSDRKRELEQQLSTIMEENEQLQGLVEELQDKELSLNQQNFGKDLQLRESQLEIEEMRLSYRQLEGKLEELREEKSLQHMNSTSTSLLSEIEQSIEAEEQEQEREQLRLQLWEAHCQVRSLCCQLRGNESADSAVSTDSSMDESSETSSAKDVPAGSLRTALSELKSLILSILETCDSASSRKCEDDGLEEQIKQTSEDSRALRELLQGEQMRMKQTFDELQELHKQVTLLSVEMNALKEERDRLLVLTQNDETQEQLMKAIKDRDEAISKKTAVELELAKCRIDLMSLNTQLLDAIQQKLNLSQQLEAWQDDMHRVIDQQLMDKHQKEWSQPAYSFSNSHHVKQCSKAAAMKHAERPGEESIGAEGRRLFSFLKKTKC
What is the function of this protein?
Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin.  Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track).  Predominantly recruits 2 dyneins, which increases both the force and speed of the microtubule motor.  Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth.  Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis.
What are the official names of this protein?
BICD family-like cargo adapter 1, Bicaudal D-related protein 1, BICD-related protein 1, BICDR-1, Coiled-coil domain-containing protein 64A.
What is the protein family that this protein belongs to?
Belongs to the BICDR family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes around the centrosome.
Protein: RL19_XYLFT
Sequence: MSKLNKSIIAEFESAQITRQVPQFSQGDTIVVNVKVKEGNRERLQAYEGVVIATKNAGLNSAFTVRKISHGYGVERVFQTHSPIIESIEIKRRGKVRAAKLYYLRGLEGKAARIKEDLAATAHEKLARKTVTAKAG
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: OXND1_XENLA
Sequence: MALVAGSAAYQVLRGVTGTFPTQSATLLARAPALCAHTMNRRRMSSSQQTDHLERTANTFRQEIISPAKVCGITNESATVKRVRLAIANREFTFKAGQWVDFFIPGVPKVGGFSICSSPGLLETEGVLELAVKYNLHPPAHWIHSQCALGSEVAIRVGGEFCFDPQPSDLPLDLVLIAGGVGINPLFSILLHVADLHKTREITGRGFQMGNVKLYYCAKNTGELLFKRNILDLVNSFPGKVTCSFHVTQQSSPICRELQPFITEGRITEKDLASYVSTDQLCYICGPPPMIESMCKQLQSLHLPKERILFEKWW
What are the official names of this protein?
Oxidoreductase NAD-binding domain-containing protein 1.
Protein: PLCC_PONAB
Sequence: MGLLAFLKTQFVLHPLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSLLGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFKPARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQEFKKKE
What is the function of this protein?
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity).  Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor (By similarity).  Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA.  Has a preference for arachidonoyl-CoA as a donor (By similarity).  Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (By similarity).
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma, 1-acylglycerol-3-phosphate O-acyltransferase 3, 1-AGP acyltransferase 3, 1-AGPAT 3, Lysophosphatidic acid acyltransferase gamma, LPAAT-gamma.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope.
Protein: PAT_SALPA
Sequence: MNRLPSSASALACSAHALNLIEKRTLNHEEMKALNREVIDYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRRPFMPLLPGFRHVPFGNIDAMSMAFSEGKKTGDEIAAVILEPIQGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDTLLDSFRQLAREYPNLVHEARGKGMLMAIEFVDNETGYRFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIELCEQVLKSARNALAAMQVSVEEV
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: ANMK_SALNS
Sequence: MKSGRFIGVMSGTSLDGVDVVLAAIDETMVAQQASLTWPIPVHLKKGILDICQGQPLTLSQLGQLDTQLGRLFAQAVNALLARQRLQPRDIVAIGCHGQTVWHEPTGEAPHTLQIGDNNHIVAHTGITVVGDFRRRDIALGGQGAPLVPAFHHALLGHPTEKRMVLNIGGIANLSLLFPGQAVRGYDTGPGNMLMDAWIWRQCAQPYDKDAAWAKEGQVILPLLQKMLRDPYFAASAPKSTGREYFNYGWLERHLTAFPGADARDVQATLAELTAVSIAQQVLLNGGCERLMVCGGGSRNPLVMARLAALLPGIEVSTTDKAGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGATEASVLGAIYPANPITQS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: PSA5_HUMAN
Sequence: MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKDI
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit alpha type-5, Macropain zeta chain, Multicatalytic endopeptidase complex zeta chain, Proteasome zeta chain.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
Protein: ECTD_HALED
Sequence: MSVQTSSNRPLPQANLHIATETPEADSRIRSAPRPGQDPYPTRLSEPLDLPWLNRREPVVKGEEADGPLSAAQLDTFERQGFIFEPDFLKGEELEALRHELNALLARDDFRGRDFAITEPQGNEIRSLFAVHYLSRVFSRLANDERLMGRARQILGGEPYVHQSRINYKPGFEGKGFNWHSDFETWHAEDGMPAMHAVSASIVLTDNHTFNGPLMLVPGSHRVFVPCLGETPEDHHRQSLKTQEFGVPSRQALRELIDRHGIEAPTGAAGGLLLFDCNTLHGSNANMSPDPRSNAFFVYNRRDNRCVEPYAASKRRPRFLAHEPDEAWSPDG
What is the function of this protein?
Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte.  Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.
What are the official names of this protein?
Ectoine dioxygenase, Ectoine hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PhyH family. EctD subfamily.