PharMolix/UniProtQA huggingface dataset:
Protein: FETP_POLNA
Sequence: MARLVNCIKLGREAEGLDFPPYPGALGKRIWEEVSKQAWADWMKQQTMLVNENRLNLADARARQYLARQMEKHFFGDGADAVQGYVPPTPPGA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: KAE1_PYRFU
Sequence: MIALGIEGTAHTLGIGIVTENKVLANVFDTLKTEKGGIHPKEAAEHHAKLLKPLLRKALEEAGVSMEDIDVIAFSQGPGLGPALRVVATAARALAIKYNKPIVGVNHCIAHVEITKMFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNALDVFARELGLGFPGGPKIEKLALKGEKYIELPYAVKGMDLSFSGLLTEAIRKYKSGKYRVEDLAYSFQETAFAALVEVTERALAHTEKEEVVLVGGVAANNRLREMLRIMAEDRGVKFFVPPYDLCRDNGAMIAYTGLRMYKAGIKFKLEETIVKQKFRTDEVEVVW
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBH_GUITH
Sequence: MNKSQLISKIAYYTKYSKTDIEKIITSMLEIIVDTVATGEKVTLVGFGSFEARERKAREGRNPRTGEKLFLPASRIPTFSVGNFFRNKVNKTF
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU homolog, Histone-like protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: URE2_CLOPF
Sequence: MIPGEFKFGQGKILCNADKKAITIEVKNTGDRAVQVGSHYHFYEVNSALDFDRKLAWGKKLDIPSGAGVRFEPGDVKKVNLVDFTGERRIFGFHDEVNGYLD
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_HAES1
Sequence: MQLNHPIRQALLSVSDKSGIVEFAQGLVKRGVKLLSTGGTAKLLAENGIPVTEVSDYTGFPEMMEGRVKTLHPKIHGGILGRRGIDDEVMMQHQIDAIDMVVVNLYPFAATVAKPDCTLEDAVENIDIGGPTMVRSAAKNHQHVAIVVNNSDFNAILAEMDQNRNSLTLETRFDLAIKAFEHTAQYDSMIANYFGQMVKPYFRAEEEAEAKCGQFPRTLNLNFIRKQSMRYGENGHQKAAFYVEQDVKEASVSTAKQLQGKALSYNNIADTDAALECVKSFSEPACVIVKHANPCGVALGKDILEAYNRAYQTDPTSAFGGIIAFNRELDEDTAKAIIERQFVEVIIAPTVSSAAQEIVKSKKNVRLLTCGNWESAIQRLDFKRVNGGLLVQEADLSMVDLADLEVVSKRQPTKQELEDLLFCWKVAKFVKSNAIVYAKNNQTVGIGAGQMSRVYSAKIAGIKAKDEGLEVKGCVMASDAFFPFRDGIDAAAKVGIECVIHPGGSMRDQEVIDAANEHNMVMVLTKMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: ATPG_PERMH
Sequence: MAKLSPRDIKRKIQGIKNTQRITKAMKAVSAAKLNKAKAKLNATRPYSERLYDLINDLAMFVDRDIHPLLKIRDEHKVDIVVVTADRGLAGAFNSYVIKTTLGKVKELQEAGKDVNLILIGRKAVQFFKNKGFNIIAEYEDIYRDHMNLSFTSQVGGIIAERYENEKTDAVYLINNELITTATYETKVRKLFPIEPELDYTKLSEISRYNIEPSSEEVLEQLLKRYINFQLYRALVESSTAEHAARMIAMDNATRNAGEAIKRWTIIFNKARQEAITTELIDIINASNAIE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YSMA_BACSU
Sequence: MKLPAYIDMPFQEWKTSFSFFNKVSVRFSETDMFGHMNNVTPFIYFEEVRISYFKKLNMMSENKQTMTVVASQQCDYLRQVMPYEELRIYVKTSAVGSSSLTLHYLGENLEGEPCFTGAVVMVQVSKESGKAVSWTDEEKETLLHTR
What are the official names of this protein?
Uncharacterized protein YsmA.
Protein: NPC5_ARATH
Sequence: MAETKKGSESYPIKTIVVLVQENRSFDHTLGWFKELNREIDGVMKSDQKFNPGFSSDLNSHNVVFGDQSQYVDPNPGHSIRDIYEQVFGKPWDSGHPDPNPGPATMSGFAQNAERKMKGMSSAVMNGFKPDALPVYKELVQNFAICDRWFASVPGATQPNRLFIHSATSHGTTNNERKLLIEGFPQKTIFESLDEAGFTFGIYYQCFPTTLFYRNLRKLKYLTRFHDYGLQFKKDCKEGNLPNYVVVEQRWYDLLLNPANDDHPSHDVSEGQKLVKEVYEALRSSPQWNEILFIITYDEHGGFYDHVPTPLDGVPNPDGILGPPPYNFEFNRLGVRVPTFFISPWIEPGTVLHGSNGPYLMSQYEHSSIPATVKKIFKLKDFLTKRDSWAGTFESVITRNSPRQDCPETLSNPVKMRGTVAKENAELSDFQEELVIVAAGLKGDYKNEELLYKLCKKTCVSDASKYVTKAFDKFVEESKKARERGGDENDIVFCVDDDDDHNVVKPPPSQSEPSHATPWSN
What is the function of this protein?
Non-specific phospholipase C (PLC) which assumes minor PLC activity during inorganic phosphate starvation.  Can hydrolyze both phosphatidylcholine (PC) and phosphatidylethanolamine (PE).  Required for normal accumulation of digalactosyldiacylglycerol (DGDG) during phosphate limitation and may contribute to the conversion of phospholipids to diacylglycerol, the substrate for galactolipid synthesis.
What are the official names of this protein?
Non-specific phospholipase C5.
What is the protein family that this protein belongs to?
Belongs to the bacterial phospholipase C family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: HMCS2_HUMAN
Sequence: MQRLLTPVKRILQLTRAVQETSLTPARLLPVAHQRFSTASAVPLAKTDTWPKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV
What is the function of this protein?
Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate.
What are the official names of this protein?
Hydroxymethylglutaryl-CoA synthase, mitochondrial, HMG-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PRP1_ARATH
Sequence: MAITRASFAICILLSLATIATADYYAPSSPPVYTSPVNKPTLPPPVYTPPVHKPTLPPPVYTPPVHKPTLSPPVYTKPTLPPPAYTPPVYNKPTLPAPVYTPPVYKPTLSPPVYTKPTLLPPVFKPTLSPPVYTKPTLSPTVYKPTLSPPVNNKPSLSPPVYKPTLSPPVYTKPTLPPPVYKKSPSYSPPPPFAPKPTYTPPTKPYVPEIIKAVGGIILCKNGYETYPIQGAKAKIVCSERGSYEKSKNEVVIYSDPTDFKGYFHVVLTHIKNLSNCRVKLYTSPVETCKNPTNVNKGLTGVPFSMYSDKNLKLFNVGPFYFTAGSKAAPATPRY
What is the function of this protein?
May contribute to cell wall structure in root hairs.
What are the official names of this protein?
Proline-rich protein 1, AtPRP1, Protein ROOT HAIR SPECIFIC 7.
What is the protein family that this protein belongs to?
Belongs to the plant proline-rich protein superfamily. ENOD12 family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: COX2_LEPOC
Sequence: MAHPSQLGFQDAASPVMEELLHFHDHALMIVFLISTLVLYIIVAMVSTKLTNKHILDSQEVEIVWTILPAVI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYSN_ALIB4
Sequence: MSDLENKIATDIESYLKEHENKQLLRFITCGSVDDGKSTLIGRLLHDSKMIFEDQLAAIKKDSKKVGTTEGEFDLALLVDGLQSEREQGITIDVAYRYFTTDKRKFIIADTPGHEQYTRNMATGASTADLAIILIDARYGVQTQTRRHSFITKLLGIKHIVVAVNKMDLVDFKEDIFNQISSDYLKFAQELGMTKDITLIPISALNGDNIVKRSEKSPWYKGDTLMNLLETIKIDEDRDLVHFRFPVQYVNRPNLNFRGFCGTIASGVIKVGDAITVLPSGKSSTVKEIVTYDGNLDYAYSQQAITLTLNDEIDISRGDIIVKSDEQPDHASNLDVDIVWMSEEPLIKGKQYFIKRATTVTVGSIDHFYYKTDVNTLEQSEANVLNLNEISRAKLDLEQVIAFDSYDKNKVMGSFIIIDRITNNTVGAGMIRNKSEDQSKKDSIYSDFEIEFNALVRKHFPHWECKEIF
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: DNAJH_SYNY3
Sequence: MASTDFKDYYQILGVTKTASEAEIKKQFRKLALKYHPDKNPGDKAAEEKFKEISEAYEVLSDPEKRQKYDQFGRYWQQAGTAGQPSGSYGPGVGVDFGGFDFSQYGNFDEFINELLGRFNTPGGGGQRTSYSYSTGGPGFNDFGGFGNAQAPAGDREATLQLTLAEAFRGVEKRLNLGEEMVTVRIPAGAKNGSRVRVRGKGMASPYGQRGDLYLNLQLTPHPFFQFEGDNLVCELAIAPDEAVLGADISVPTPDGMVRMKVPAGVKSGQSLRLKGKGWPNPKQGRGDQLVRLIITAPKNPSAIERECYEKIQAQRTENPRQAVEKYANLLA
What are the official names of this protein?
DnAJ-like protein slr0093.
Protein: HBA_MYOVE
Sequence: VLSPADKTNIKAAWDKVGAHAGDYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVGDALGNAVAHMDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLACHLPGEFTPAIHASLDKFLASVSTVLVSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GHRB_SHIF8
Sequence: MKPSVILYKALPDDLLQRLQAHFTVHQVANLSPQTVVQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHVAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGA_HAEIN
Sequence: MKYALINCVIYTKYDVLRDFAVIINGEIIEAVIPQAELETGIKTIDLQGNNLTAGFIDLQLNGCGGVMFNDQTSVETLEIMQETNLKSGCTSFLPTFITAPDENIKSAVKIMREYLNKHKNQALGLHIEGPYLSIEKKGVHRPEYIREITPEMKDFLCENGDVITKMTIAAENPTINYTPDFVKAGIIVSVGHSNATYEVAKAAFHKGATFATHLHNAMSPISSGREMGVVGAVLDSDVYTGIIVDGVHINYGNVRIDKKIKGDKLCIVTDSIAAAGAPPELESFTFVGKTIYIKEGRCYDANDTIAGASITMMESIKNAVEYVEIPLAEAIRMSNLYPARAIGIDDRLGSVEKGKIANLAVFTPNYQVIGTVVNGKWKEN
What is the function of this protein?
Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides.  Catalyzes the hydrolysis of the N-acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate.
What are the official names of this protein?
N-acetylglucosamine-6-phosphate deacetylase, GlcNAc 6-P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. NagA family.
Protein: CH60_BUCTS
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPAITKDGVTVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIVTEGLKAVAAGMNPMDLKRGVDKAVIAAVEELKCLSVPCSDFKAIAQVGTISANSDETVGKLIAEAMEKVGKEGVITVEEGTGLQDELDVVEGMQFDRGYLSPYFINKPDTGSIELDNPFILLADKKISNNREMLPPLESVAKAGNLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGSTVISEEIGLELEKTTIEDLGHAKRVVINKDTTTIIDGIGNESAIKGRVVQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVAGKISSLTGENEDQNVGIKVAIRAMESPLRQIVINAGEEASVIANNVKAGKGNYGYNAYSEQYGDMIKMGILDPTKVTRSALQYAASVAGLMITTECMITDLPKSDSSDLSNAGNGGMGGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTA_HUMAN
Sequence: MSGGRAPAVLLGGVASLLLSFVWMPALLPVASRLLLLPRVLLTMASGSPPTQPSPASDSGSGYVPGSVSAAFVTCPNEKVAKEIARAVVEKRLAACVNLIPQITSIYEWKGKIEEDSEVLMMIKTQSSLVPALTDFVRSVHPYEVAEVIALPVEQGNFPYLQWVRQVTESVSDSITVLP
What is the function of this protein?
May form part of a complex of membrane proteins attached to acetylcholinesterase (AChE).
What are the official names of this protein?
Protein CutA, Acetylcholinesterase-associated protein, Brain acetylcholinesterase putative membrane anchor.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
Protein: GLPK_FRAP2
Sequence: MSKQFILAIDQGTTSSRAIIFDKKGNIKKIAQKEFTQIYPKSGWVEHDPMEIWASQSSIVREALEYARVSPRDIAAIGITNQRETTVVWDKNTGQPVYNAIVWQCRRTSHICDEINKNEDLKKYIRKNTGLIVDAYFSATKIKWILDNVDGAREKAEKGDLLFGTIDTWLIWNLTKGEVHATDFSNASRTMLFNINTLEWDKKILEYLDIPVSMLPEVRSSSGDFGHTHPSTLGGARIPIAGVAGDQQSALFGHCCFEEGMAKNTYGTGCFALMNVGDKPVFSDAGLLTTIAWAEDGKPTYALEGSVFIAGAVIQWIRDGLGLVRSAEDSEYYATKIDSTDGVYLVPAFVGLGTPYWDMYARGTIVGITRDTRREHIIRAALEAIAYQAKDVLDCMKEDTGLDWAGLRVDGGAVQNNFLMQFQSDILQSEISKPKINEITGLGAVFLAGLAVGFWKDKEELKTILTTEKTFEPKKDPETVAHDYKGWKKAVQRSMAWAE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: SPT2_MOUSE
Sequence: MDFREILLIASKGQGVNHVPKRYSLAVGPPKKDPKVKGVQSAAVQAFLRRKEEELRQKALEEKKRKEELVKKRIELKHDKKARAMAKRTKDNFHGYDGIPVEEKTKKKQLVESHLNQGTDQEYDVEEEDFIDYNQAELDQDYEEEQEPPKAESKPKAPLKSAPSPMNFTDLLRLAEKKQFEPVEIKVVKKAEDRPLTAEELREREFLERKHRKKKPEPDAKLPPPVLKKAPSHKDIMGTKPSRGAGDRQLASKGLPFPQAEKKFRPSTASEKQAALSSPKSLPGERTKVGSGSSTQPSLREGHNRPVFNGAGKPRPSTCSPSVPKTPASGTQKSASEHKAKKPLPSHPSHSKPGPTVLSHNKSKSPGVRQPGSNSGSAPGQPNPGTARPTLSSGPVPRRQNGSSSSGPEQSAGGIRKLASNSHLSGRTLNGTNGPGRPASSSSGPGRPISGSAGSGRPVGSSGGPGQPVNNPHDLRRPMNSLSSPGRAVSGPGRSISGSIPAGRTVNSGPGRPVSSLGPGRAVSNPGLPTKPRCTVVSETISSKNIISRSSNGQINGMKPLLSGYRSAQGPQRLPFPTGYKRPREYEEDDDDEYDSEMDDFIEDEGEPQEEISKHIREIFGYDRKKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEELKRRKAKKLKRH
What is the function of this protein?
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin.  Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription.  Binds DNA and histones and promotes nucleosome assembly (in vitro).  Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (By similarity).  Modulates RNA polymerase 1-mediated transcription (By similarity).  Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (By similarity).
What are the official names of this protein?
Protein SPT2 homolog, SPT2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SPT2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RLMH_STAEQ
Sequence: MKITILSVGKLKEKYWKQAIAEYEKRLGPYTKIELIEVPDEKAPENMSDKEIEQVKEKEGQRLLNKIKPQSTVITLEIKGKMLSSEGLAKELQTRMTQGQSDFTFVIGGSNGLHQDVLQRSNYALSFSNMTFPHQMMRVILIEQIYRAFKIMRGEAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECD_ECO57
Sequence: MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVALNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLREKGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDARLSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQSRLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIEQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATA_STRPJ
Sequence: MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRRDQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDFLVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVVSIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVIDAFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPELIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVSPPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKEKTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFDSVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSEDRLDEIKIISNEITHQIHLILETGGL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: M2H81_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSEENEIQSLSQRDVLEEESLREMRGIGTKILGGVKTALKGALKELASTYVNGKRTAEEHEVMKRLETVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKRILGPVLGLVSNALGGLLKNIG
What is the function of this protein?
Maximin-H8 shows antimicrobial activity against bacteria and against the fungus C. albicans.  Shows strong hemolytic activity (By similarity).
What are the official names of this protein?
Maximins 2/H8 type 1.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL9_BACHK
Sequence: MKVIFLKDVKGKGKKGEVKNVPDGYANNFLLKQGLAAEATNSSMKTLEAQKRKEEKDAAAELESAKQLKETLEKLTVELKAKSGEGGRLFGSITSKQIVDAMQKSHKIKLDKRKFEMDDAIRALGYTNVTVKLHPQVTATVKVHVSEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: TCRA2_MYCTO
Sequence: MADETTMRAGRGPGRACGRVSGVRILVVEDEPKMTALLARALTEEGHTVDTVADGRHAVAAVDGGDYDAVVLDVMLPGIDGFEVCARLRRQRVWTPVLMLTARGAVTDRIAGLDGGADDYLTKPFNLDELFARLRALSRRGPIPRPPTLEAGDLRLDPSEHRVWRADTEIRLSHKEFTLLEALIRRPGIVHTRAQLLERCWDAAYEARSNIVDVYIRYLRDKIDRPFGVTSLETIRGAGYRLRKDGGRHALPR
What is the function of this protein?
Member of the two-component system HK/TcrA.
What are the official names of this protein?
Transcriptional regulatory protein TcrA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_CHLAA
Sequence: MKANELRALDDAQLREKLAEYKVELFNLRFQKATGKLTNTARPRLVKKEIARILTILRERELAQAELG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: GRPE_BRUSI
Sequence: MADEKNKPENPDLDQRDINNPRDREALKQAADNFLKARRAEARAEAAADEAEGEVDETANRIAVLEADNTELKDQMLRVAAEMENLRKRTQRDVQDARAYAITNFARDMLSVSDNLRRALDAIPADALEADSNLKSLSEGVEMTERAMLLALERHGVKKLEPEGQKFDPNFHQAMFEVPNPDLPNNTVVQVVQAGYAIGDRVLRPAMVGVSKGGPKVSAENGASTSEDNA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.