PharMolix/UniProtQA huggingface dataset:
Protein: RLMI_VIBPA
Sequence: MTAAIYLVKGREKSVKRKHPWIFSRGIGKVEGEPALGETVDVFTHDGKWLAKAAYSPESQIRARIWSFEKEEINKAFFVKRFQNAQLLREDVIERDGLTGYRLIAAESDGLPGVTIDRYQNFFVCQLLSAGAEYNKQAIVDALVECFPDCNVYERSDVAVRKKEGLKETTGVLHGEEPPKSVVIEENGVKISVDIVGGHKTGFYLDQRDSRQQAMKYVKDKEVLNCFSYTGGFGLYALKGGAKRVINADVSQPALDTAKYNAELNEFDISKKRAVFLNADVFKLLREYRDQGTQFDVVIMDPPKFAESKAQLNGACRGYKDINMLALQILKPGGTLLTYSCSGLMDQVLFQKIIADAAVDANRQVKFVERFEQAADHPTDTAYPEGFYLKGFACKVL
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_TERTT
Sequence: MAGKHTQLEELIAPVVESLECELWGLEYSVQGRRSMLRIFIDKQPDGVLVEDCEKVSRQVSSVLDVEDPISGEYTLEVSSPGMDRPLFKLAHFELYVGHRVALRLRVAFEGRRKFQGLLKGIEDGEIVLEVGEEEYLLPFELIDKANVVPQF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_METC4
Sequence: MTPEEVLEEFRSAGALLQGHFILSSGLRSSTFLQKMTIFSDPARTERLCRALAEVITARFGRIDIVVSPAIGGIIPGYETARHLGAKAIFVERDPGGPFTLRRGFSIPAGTRAVIVEDIVTTGLSARECLASLKDEAGEVVGAACLIDRSGGRGAIGLPLLSLVTLDIPTYAPDALPAELAAIPPVKPGSRALSKP
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: NBDY_PONAB
Sequence: MGDQPCASGRSTLPPGNAREAKPPKKRCLLAPRWDYPEGTPNGGSTTLPSAPPPASAGLKSHPPPPEK
What is the function of this protein?
Promotes dispersal of P-body components and is likely to play a role in the mRNA decapping process.
What are the official names of this protein?
Negative regulator of P-body association, P-body dissociating protein, Protein NoBody.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Localizes to P-bodies at low concentrations without dissociating them.
Protein: MMP1_HORSE
Sequence: MLSLPLLLLLLWGMGSHSFPTVPSETREEDVEMVQKYLENYYNLKSDGEQIEKQRHRSPVVEKLKQMQEFFGLKVTGKPDAETLNVMKQPRCGVPDVAEFVLTEGNPRWENTHLTYRIENYTPDLPRADVDQAIEKAFQLWSNVSPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPRIGGDAHFDEDETWTSNFRNYNLYRVAAHEFGHSLGLSHSTDIGALMYPNYFFTGDVQLSQDDINGIQAIYGPSQNPIQPIGPQTPEVCDSKLTFDAITTIRGEVMFFKDRFYMRINPYYPEAELNFISIFWPQLPNGLQAAYEVSHRDEVRFFKGNKYWAVKGQDVLYGYPKDIHRSFGFPSTVKNIDAAVSEEDTGKTYFFVADKYWRYDEYKRSMDAGYPKMIADDFPGIGDKVDAVFQKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
What is the function of this protein?
Cleaves collagens of types I, II, and III at one site in the helical domain.  Also cleaves collagens of types VII and X.
What are the official names of this protein?
Interstitial collagenase, Matrix metalloproteinase-1, MMP-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: PRT1_ESOLU
Sequence: PRRRRASSGRPVRRRRRPKMSRRRRRGGRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-1, Protamine-I.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RSXG_SALTY
Sequence: MLKTIRKHGITLALFAAGSTGLTAVINQMTKSTIHEQALQQQHALFDQVLPPDRYNNNLQESCYLVDAPALGKGTHRVFIARKDDKPVAAIIEATAPDGYSGAIQLIVGADFNGTVLGTRVTEHHETPGLGDKIERRLSDWITHFSGKTISGENDTHWAVKKDGGDFDQFTGATITPRAVVNAVKRAGLYAESLPAQLPHLTACGE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Rsx electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RPOA_IPOPU
Sequence: MIREKVTVSTRTLQWKCVESRTDSKRLYYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRVKSEKAPHEYSTIAGIQESVHEILMNLKEIVLRSNLYGTCDASICVKGPGCVTAEDIILPPSVEIVDNTQHIAWLTEPIDFCIGLQIERNRGYILKTHHNFEDGSYPIDAVFMPVRNANHSIHSYGNGNEKQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHMEEENLHLEDGEHTIPLSPLSFHDKVAKLRKNKKKLALKSIFIDQLEFPPKIYNCLKKSNISTLLDLLNKSQEDLMKIEHFHIEDVKQILGILEKHFAIDLPKNQF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DIAA_ECODH
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: HEM3_PSEAE
Sequence: MSSREIRIATRQSALALWQAEYVKARLEQAHPGLTVTLLPMTSRGDKLLDAPLAKIGGKGLFVKELETALLEGAADIAVHSMKDVPMDFPEGLGLYTICEREDPRDAFVSNTYASLEQLPAGSVVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFESRIRSSISVDDSLPAGGQGAVGIECRTADSDLHALLEPLHHTDTALRVTAERALNKRLNGGCQVPIACYAIREGDQLWLRGLVGQPDGTQLLRAEGRAPLAEAEALGVRVAEDLLEQGAEAILEAVYGEAGHP
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ASTB_NITMU
Sequence: MNAYEANFDGLVGPTHNYGGLAVGNIASAESALTNSNPREAALQGLEKMKRLADLGLMQGVLPPQERPAVSVLRKLGFTGEDATIIRCAAKVAPGLLRACSSASSMWVANAATVSPSADTEDGKVHLTAANLPSQFHRSIEAPVTSAVLKRVFSNERYFVHHDPLPSNLYFGDEGAANHMRLCPRHGEPGVEIFVFGRSASRDIPKPLRFPARQSLEASEAVARLHQIKRGKELFVQQGPAAIDAGAFHNDVLAVANCDVLFYHEAAYRDWEETEARITKACDWPIHFIRTGEEDVTLAEAVRTYLFNAQLLTLPGNEMMILAPSECRDSHSARNFLERVVQDAANPIAHVEYVDLRQSMKNGGGPACLRLRVVLTEPELDAVQENSRVILDECLYNDLKAWIEKHYRECLSPTDLGDPALLQESRAALDELTTILGFGSLYDFQRP
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: NRDR_FRASN
Sequence: MRCPFCRHPDSRVVDSREAEEGAAIRRRRSCPACGRRFTTMEEASLRVRKRSGATEPFSRAKVIVGVRKACQGRPVRSDDLALLAERVEETVRSSGSAEVAAEDVGRAILGPLRELDEVAYLRFASVYLAFESLGDFEAAIAALRAESAGGGEPPVAGKPTTMPAATGASAVIVPVTTGPRAAAGP
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PADL_ECOLX
Sequence: MKLIVGMTGATGAPLGVALLQALREMPNVETHLVMSKWAKTTIELETPYSARDVAALADFSHNPADQAAIISSGSFRTDGMIVIPCSMKTLAGIRAGYADGLVGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAMVPPMPAFYNHPETVDDIVHHVVARVLDQFGLEHPHARRWQGLPQARNFSQENE
What is the function of this protein?
Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase C.  Involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions.
What are the official names of this protein?
Probable UbiX-like flavin prenyltransferase, 4-hydroxybenzoate decarboxylase subunit B, Phenolic acid decarboxylase subunit B.
What is the protein family that this protein belongs to?
Belongs to the UbiX/PAD1 family. YclB subfamily.
Protein: AGRE4_MOUSE
Sequence: MLMGATRDMGSRCLLHASVPGMLLIWSILQMMNISASCPQCNENASCFNSTHCVCKEGFWTGSENRRIIEPHEKCQDINECLLKELVCKDVSYCRNKIGTYICSCVVKYPLFNWVAGIINIDHPDCYVNKSKNTGSKTHTLGVLSEFKSKEEVAKGATKLLRKVEHHILNENSDIPKKDENPLLDIVYETKRCKTMTLLEAGNNTMKVDCTSGFKEHNSGGETAVAFIAYKSLGNLLNGSFFSNEEGFQEVTLNSHIVSGAIRSEVKPVLSEPVLLTLQNIQPIDSRAEHLCVHWEGSEEGGSWSTKGCSHVYTNNSYTICKCFHLSSFAVLMALPHEEDGVLSALSVITYVGLSLSLLCLFLAAITFLLCRPIQNTSTTLHLQLSICLFLADLLFLTGINRTKPKVLCSIIAGMLHYLYLASFMWMFLEGLHLFLTVSNLKVANYSNSGRFKKRFMYPVGYGLPAFIVAVSAIAGHKNYGTHNHCWLSLHRGFIWSFLGPAAAIILINLVFYFLIIWILRSKLSSLNKEVSTLQDTKVMTFKAIVQLFVLGCSWGIGLFIFIEVGKTVRLIVAYLFTIINVLQGVLIFMVHCLLNRQVRMEYKKWFHRLRKEVESESTEVSHSTTHTKMGLSLNLENFCPTGNLHDPSDSILPSTEVAGVYLSTPRSHMGAEDVNSGTHAYWSRTISD
What is the function of this protein?
May mediate the cellular interaction between myeloid cells and B-cells.
What are the official names of this protein?
Adhesion G protein-coupled receptor E4, EGF-like module receptor 4, EGF-like module-containing mucin-like hormone receptor-like 4, F4/80-like-receptor, Seven-span membrane protein FIRE.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EXC_ECOLX
Sequence: MKAKKETTDRFPTWWLFYYVLRKAYFFLGIPFFLFCALGFTEMLCSDRYFGNKVEDYVVTFGSWFLLLAPGIWMYSRAKTRREKIRKVVQTIKESGFYSPEKGYEGLSLTQGAYFGIDLKNGTMLYVRIYPGNIMDVIGFDIHNFTRTVTDDKKLEIHTKYINLPMVPVPSWCAHPETASNTMHAMASRGYDYPVDFPRLIQEKRKEWEQIAGMPVAEVF
What are the official names of this protein?
Exclusion-determining protein.
Protein: A28_RFVKA
Sequence: MNPVTVFFVVVVTVAACMILFQVYSIYLNYDNIKEFNAMHSPLEYSKMVNVTAIDRRIQDANDDIYDAKQKWRCVKLDDSYVSLSMFGYKSDGIGIRRFRTLNSCIDYTFSTSTHSSILNPCISPNDPKSRECTFLKSVL
What is the function of this protein?
Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).
What are the official names of this protein?
Envelope protein A28 homolog, Protein Gp116.
What is the protein family that this protein belongs to?
Belongs to the poxviridae A28 protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Note=Component of the intracellular mature virion (IMV) membrane.
Protein: MUTS_PROMA
Sequence: MTAENTPLQGNLFVESEENLLDANSLQNTNSVKDSNLNDEELSKNAELRPRKRKKSVLLQNSVGEQTEDFSNDERPAWSHHSLVEINELTPVLRHYVELKQKHPERILLYRLGDFFECFFEDAIGLSELLELTLTGKEGGKKIGRVPMAGIPHHAAERYCSTLIQKGLSVAICDQLESIQNKEGKLLKRGITRILTPGTVLEEGMLQAKKNNWLAAILIESNSQTNQLKWGLASADISTGEFTVKEGNGIDTLEQDLLNIEASEIICEQLDVDISKKWQSNRIKITQQSKTSFSLQEAKAILKKHYNLKTINGLGLNETELALRAAGGLLYYLKETNPIHNIGVKNKCSKVVLDFPKNNLRGDSLIIDAQTRRNLELTKTQKDGHFQGSLLCAIDRTLTAMGGRCLRRWIENPLINSELILQRQRLITLLVEKRPLRKALRNLLRTMGDIERLSGRASAGQAGARELVAIADCLEKLPKLAANLQNLSINPPKWFSKLENINPELTKLAEEIKDKLIDNPPLSITEGNLINDSVDKILDGLRNQLDDQNEWLSNQEKKERNISGNNNLKLQHHRTFGYFLAVSKSKANTVPDHWIRRQTLANEERFVTPALKERESKIFQLKVKAANREYDLFCALRELVGGYAPIIRETAKAIAGLDVLLGLAELASTNNYCAPNIIDKKSLSNSRSINIKGCRHPVVEQMLVEEKFQANDIELGDGVDLIILTGPNASGKSCYLRQIGLIQILSQIGSWIPADKASISIADRVFTRVGAVDDLAAGQSTFMVEMAETAFILNQATQDSIVLLDEIGRGTSTFDGLSIAWSVSEFLAENIKSRTIFATHYHELNELAKKMGNVANFQVLVHETGEDIHFLHQVIPGGSNRSYGIEAARLAGVPKSVINRARGVLKRLEEKNKG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: H18_HUMAN
Sequence: MAPGSVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAEA
What is the function of this protein?
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure.  Essential for meiotic maturation of germinal vesicle-stage oocytes.  The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte.  The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure.  The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity).
What are the official names of this protein?
Histone H1.8, Histone H1oo, Oocyte-specific histone H1, Oocyte-specific linker histone H1, osH1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome.
Protein: GABT_BOVIN
Sequence: MASMLVAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGRLMKTEVPGLRCQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPGLLKLIQQPQNASMFVNRPALGILLPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENGLKTIFMWYRSKERGQRGFPQEELETCMINQAPWCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIPRKQCCAFLVDVVQTGGGCTGKFWAHEHWARDDPEDVMTSSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK
What is the function of this protein?
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively.  Can also convert delta-aminovalerate and beta-alanine.
What are the official names of this protein?
4-aminobutyrate aminotransferase, mitochondrial, (S)-3-amino-2-methylpropionate transaminase, GABA aminotransferase, GABA-AT, Gamma-amino-N-butyrate transaminase, GABA transaminase, GABA-T, L-AIBAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: YO24_CAEEL
Sequence: MHTLILFRTVHSVSNFYIFSSTILLTSAVILAIFFFFGDGFFREKYRREFSTNSKEKDGNKNLTTVE
What are the official names of this protein?
Uncharacterized protein ZK688.4.
Protein: RAPZ_ENT38
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPELARTLADRQISAAVSIDVRNMPESPEVFEQAMSSLPETFTPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDEESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKT
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: CYAS_METPE
Sequence: MSGDYQLRCPTCGLRITDRYSSFCPAGHPGLLVTDYPERTLSLSGQPGIFRYESWLPVRGRLPFTGGTVTYQSDGLAEELGLAHLFIGFNGYWPERGADLVTCSFKELEAVPSMLRATERTAGILVVASAGNTARAFCQVSALTGIPVVIVVPQSALPRLWTTEPAPAALVIGVDGDYADAIAYSTALAAVDPRLIVEGGARNVARRDGMGTVMLDGAVTIGRIPDHYVQAVGSGTGGVAAYEAASRLIRDGRFGGRLPILHLAQNLPFVPMVAAWEEHTRDLQVGPGTPYTEEAEQWVSAPVLTNRTPPYGVPGGTYDALEATGGEMYAISNGLARAAGTLFTDCEGIDLDPAAAVATASLIQAIEMGTIEPGSRVLLNITGGGYDRVVEDHTLVPTPAGYRVPAGNPDDEIRRDVITWVNDHA
What is the function of this protein?
Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
What are the official names of this protein?
Cysteate synthase, CS, Cya synthase.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family. Cysteate synthase subfamily.
Protein: SWS_DROVI
Sequence: MDVLELLRASANGCYNTLFSDAWFQYVSKQIATTMYWYGALLVIGVLFIAWFLYFKRLARLRLRDEIARSLSAVTSSGGDHRGLRFRKRDKMLFYGRRMLRKMKNVSGQMYSSGKGYKRRAVMRFARRILQLQRENRPLEMKTVEPPAEYLEETIEGSDRVPPDALYMLQSIRIFGHFEKPIFLKLCKHTQLLQLMAGDYLFKITDPDDSVYIVQSGMINVYICNADGSTLSLKTVRKGESVTSLLSFIDVLSGNSSYYKTVTAKAMEKSVVIRLPMQAFEEVFEENPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRTKGSSVVPNAVGGAVLAQASQASRPVVRAPTSPNSRLSREEHTLSDPDPNPNANALLFAEVHGDAPYIDLYHHQQQQSSAVSVNQAGTRRSSTTYGPSGESPNGNANTAPGTSIDQRLVQSSAVDSLRRELGLSEDDAQIIEPFVEVRELEPNVTLITEGNAEDVCVWFVMTGTLAVYQSNADATRATKQDSKNDVLIHFVHPGEIVGGLAMLTGEASAYTIRARSNSRVAYIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDESSDSTYIVLSGRMRSVITHPGGKKEIIGEYGKGDLVGIVEMITETSRTTTVMAVRDSELAKLPEGLFNAIKLRYPIVVTRLISFLSHRFLGSMQTRGSNAAGGPVEANPVTHKYSTVALVPITDDVPLTPFTYELYHSLCAIGPVLRLTSEVVRKQLGINIFEAANEYRLTSWLAQQEDRNIITLYQCDSSLSPWTQRCMRQADVVLIVGLGERSHLVGKFEREIDKLAMRTQKELVLLYPETTNAKPANTLSWLNARPWVTKHHHVLCVKRIFTRKSQYRINDLYSRVLLSEPNMHSDFSRLARWLTGNSIGLVLGGGGARGAAHIGMLKAIQEAGIPIDMVGGVSIGALMGALWCSERNITTVTQKAREWSKKMTKWFLQLLDLTYPITSMFSGREFNKTIHDTFGDVSIEDLWIPYFTLTTDITASCHRIHTNGSLWRYVRSSMSLSGYMPPLCDPQDGHLLLDGGYVNNLPGHLWRYCRASMSIAGVFPPFCDYRDGHLLLDGCYTNNVPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLYKKWNPFTSPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPPIDKYKTLAFGSFDEIRDVGYVFGKNYFDNMAKAGRLGRFNQWFNKEPPKRGNHASLNEYTFIDLAQIVCKLPETYALNTADIFSEDEDFDGYISEPTTLNMDRRRIQVPRAGNSLSFSETEMDSDVEIDLELERKVDKATQSTPPTPNKQHALSPTSSQTNLLPLPPNSKPKEKQPSYDKLDREHKRRQKSKQKQQQERSSMQQRDSMVTLHPATMAEATTQTAPHSSEEDELNKPEQQPEQKPVPETEEQQQKQQDQQQQENLTKTDTKN
What is the function of this protein?
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho).  This deacylation occurs at both sn-2 and sn-1 positions of PtdCho.  Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.  Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain.  Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain (By similarity).
What are the official names of this protein?
Neuropathy target esterase sws, Swiss cheese.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Sws tethers Pka-C3 to the membrane.
Protein: PYRB_ACICJ
Sequence: MRLPTRHLLGIEGLHPRDISALLDLAESYVLLNRSGKTRRDVLRGRTLINLFFEDSTRTRTSFELAGKRLGADVINMSVSTSSVSKGETLLDTAATLNAMNCDLLVVRHKASGAPALLAQKVDAAVINAGDGMHEHPTQALLDALTIRRNKGTLAGLTVAICGDIAHSRVARSNLLLLTAMGSRVRVVGPPTLIPSGIDQFGATVFHDMREGLRDADIVMALRLQTERMSAGLIPSAREFFTFYGLDAAKLAMAKPDALVMHPGPMNRGVEIDSQVADDATRSVIREQVEMGVAIRMAVLDVLARTALAHA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: QUEA_CHLTE
Sequence: MKVSDFDYALPEERIACYPPAKRGSTRLIVLNRATGSITHSAYASLHEELRPGDLLVLNNSRVIRARLIAHKPTGARIELMLLEKHEEAQNLALYRGRLRIGDRLLAHGVELSVEALPSDGIARLSCATGNLADLFDAHGSVPIPPYLKRDAEELDRERYQTVFAELPGSVAAPTASLNLTDELLDKINAKGVGIAHVTLHVGLGTFLPIRSERFEEHVMHREFYNIPQTAARKIGETKASGGRVVAAGTTVTRALEHAAPKLIESGFTQEVSSEADIFIYPGYEFRIIDALITNFHAPRSTVLMLTAAFAEKELLMRAYHEALDNGYRFLSYGDSMFIS
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MND1_HUMAN
Sequence: MSKKKGLSAEEKRTRMMEIFSETKDVFQLKDLEKIAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKHKLEVLESQLSEGSQKHASLQKSIEKAKIGRCETEERTRLAKELSSLRDQREQLKAEVEKYKDCDPQVVEEIRQANKVAKEAANRWTDNIFAIKSWAKRKFGFEENKIDRTFGIPEDFDYID
What is the function of this protein?
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity).  Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
What are the official names of this protein?
Meiotic nuclear division protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MND1 family.
Protein: PLSB_SHESA
Sequence: MPKQDSLWLKSLRWIQKHLVHTIVVPQDPFADLNLDASRPLAYVMKTESLSDIAALSEITTKLGLPSPYEPLVVNGVVAPRVVCLEGRKPLFGERASNEPFLECFMRLLAVHKEKPELDIQLVPVSLYWGRTPGKEDDTMKAAVLERENPTWLRKCLMILFLGRHNFVQFSNAVSLRYMADEHGTDMGIAHKLARVARVHFRRQRKVMTGPVLPNRQAMFHSLLKSESLRKAIQEEAASKKISETQARETAIEYLDEIAANYSDSLVRIAERFLTWLWNKLYSGINIKGAEQIRQLHHDGHEIVYVPCHRSHMDYLLLSYILYYQGMVPPHIAAGINLNFWPAGPLFRRGGAFFIRRSFNGNKLYTAVFREYLDQLFAKGYSVEYFSEGGRSRTGRLLAPKTGMIAMTINSVLRGIERPVTLVPVYLGYDHVMEVATYHKELSGKKKQKESVWQVFGAIRKLGNFGQGYVNFGEPITLQNFLNETAPNWRTEVADDPEQKPTWLTPAVNVLANRVMTRINDAAAASSITLTSLVLLASEQNALERCLLERQLDLYLTLLKRVPYTSFTSVAEGDGKHLVQQGLELNKFSIHADPLGEIVSIDANQAISMTYYRNNIIHLFIIPSLIASCLTNNKQISRAHILGIVSDFYPLLKAELFMGIKDLPSYVNQVLDLLIEQGLVQESDTLSVVTEHTSQMLLLAGSVSETLQRYAIIFNLLAHRPKMERSELESESHLLAQRLGALHGITAPEFYDKKLYNTLSVKLKELGYFSEKEDKSDVERIRDQANSLLRASVRQTIVASVTAEHIV
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MDCC_PSE14
Sequence: METLSFEFPAGQPPKGRALVGVVGSGDLEVLLEPGSPGKLSIQVVTSVNGASLRWKHLFERMFDGQTPPALSIDIHDFGATPGVVRLRLEQGFEEIGHD
What is the function of this protein?
Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.
What are the official names of this protein?
Malonate decarboxylase acyl carrier protein, Malonate decarboxylase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the MdcC family.
What are the subcellular locations of this protein?
Cytoplasm.