PharMolix/UniProtQA huggingface dataset:
Protein: TVBJ3_HUMAN
Sequence: MGTRLFFYVALCLLWTGHMDAGITQSPRHKVTETGTPVTLRCHQTENHRYMYWYRQDPGHGLRLIHYSYGVKDTDKGEVSDGYSVSRSKTEDFLLTLESATSSQTSVYFCAISE
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 10-3.
What are the subcellular locations of this protein?
Cell membrane.
Protein: GCSH_SALNS
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RLP47_ARATH
Sequence: MMHSSSVRRMITVKWSLCLIFCLTNSILVSAKHLCLPDQKDSLWGFKNEFNVPSPHSYAMTEKWRNNTDCCSWDGVSCDPKTGVVVELDLQYSHLNGPLRSNSSLFRLQHLQKLVLGSNHLSGILPDSIGNLKRLKVLVLVNCNLFGKIPSSLGNLSYLTHLDLSYNDFTSEGPDSMGNLNRLTDMLLKLSSVTWIDLGDNQLKGMLPSNMSSLSKLEAFDISGNSFSGTIPSSLFMIPSLILLHLGRNDFSGPFEIGNISSPSNLQLLNIGRNNFNPDIVDLSIFSPLLSLGYLDVSGINLKISSTVSLPSPIEYLGLLSCNISEFPKFLRNQTSLEYLDISANQIEGQVPEWLWSLPELRYVNISHNSFNGFEGPADVIQGGRELLVLDISSNIFQDPFPLLPVVSMNYLFSSNNRFSGEIPKTICELDNLRILVLSNNNFSGSIPRCFENLHLYVLHLRNNNLSGIFPEEAISHHLQSFDVGHNLFSGELPKSLINCSDIEFLNVEDNRINDTFPSWLELLPNLQILVLRSNEFYGPIFSPGDSLSFSRLRIFDISENRFTGVLPSDYFVGWSVMSSVVDIDGRIIQYTVTGIDRDFYHKSVALINKGLKMELVGSGFTIYKTIDVSGNRLEGDIPESIGLLKEVIVLSMSNNAFTGHIPPSLSNLSNLQSLDLSQNRLSGSIPGELGKLTFLEWMNFSHNRLEGPIPETTQIQTQDSSSFTENPGLCGAPLLKKCGGEEEATKQEQDEDKEEEDQVFSWIAAAIGYVPGVVCGLTIGHILVSHKRDWFMRIVSFFT
What are the official names of this protein?
Receptor-like protein 47, AtRLP47.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ISK1_RAT
Sequence: MKVAIIFLLSALALLSLAGNPPAEVNGKTPNCPKQIMGCPRIYDPVCGTNGITYPSECSLCFENRKFGTSIHIQRRGTC
What is the function of this protein?
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production (By similarity).
What are the official names of this protein?
Serine protease inhibitor Kazal-type 1, Cholecystokinin-releasing peptide, Monitor peptide, Pancreatic secretory trypsin inhibitor, PSTI-I.
What are the subcellular locations of this protein?
Secreted.
Protein: Y987_STRP2
Sequence: MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLTGDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SPD_0987.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CY42_TRYBB
Sequence: RKTLLTFGLNLSSSVVLTPGDSVGEHLPKSGITFIIGLVVDDIVVIEEHLRIHTKARVLVQFSDIALLYNEFVQAFNNSDGAKHLLFATSLPHWADVDTTSETVRRFHEAVPEVEKWTPLSLLGFATGRLMQRNLQRMDLATSDLLSGLFFNETFITVDDMQYGAYKDAEGVATAEESLSNFGATDISVWSMARALRSDEPVLQDPMSPSMVYTVPNGNALTPAQLDWCGWCRFACADTGSRLTVFLCCIMRNKRDNDNAPKELADPVTLIFTDIESSTAQWATQPELMPDAVATHHSMVRSLIENYDCYEVKTVGDSFMIACKSPFAAVQLAQELQLRFLRLDWGTTVFDEFYREFEERHAEEGDGKYKPPTARLDPEVYRQLWNGLRVRVGIHTGLCDIRYDEVTKGYDYYGQTANTAARTESVGNGGQVLMTCETYHSLSTAERSQFDVTPLGGVPLRGVSEPVEVYQLNAVPGRSFAELRLDRVLDVLDIFGEGTAASTSDYSSTLAELSETAQAIAVSLQSLMGVFTQAQRQGTLMPFCERWRVRCPRKVHPRGTTATVRRLSVALQ
What is the function of this protein?
Could act as a receptor for an unknown ligand.
What are the official names of this protein?
Receptor-type adenylate cyclase GRESAG 4.2, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y742_STRCO
Sequence: MTTAQPQTGTPAWRLLLSYVRPHRTALFAGALLSLVTGATGLLLPLVARELIDDLAQDRAITGALLAMSGLVVANTALGALGSYVLRRTAESVVLGARRTLSSYLLRLRIAAVDRTEPGDLMARITSDTTLLREVTTDSLIGLGTGGLTLVATLVMMGVVDPVLLGVTLAVVLGAGTVLGLIVPRINRASRQAQDAVGVMGAALERILGALRTVKASGAEPREERVLHEAAEESWRQSVRAAKWSAAAGNTAGLAMQIAFITVLAVGGARVATGAIDVGTLVAFLLFVFYLMSPIQQVVGAITQYQTGRAALGRIQDALGLPAEPQARPVPLPSAGAPPASVSFREVRFRYADDLPYIHHGVSFEVPARGMTAFVGPSGAGKTTVFSLVERFYDPDSGEITLDGRSLGDWELSSLRASIGYVEQDAPVLSGSLRDNLLLGNPEGDEATLAAVLKTTRLDGLVERLPNGLETLVGHRGTKLSGGERQRVAIARALLRRPRLLLLDEATSQLDAVNEAALRDTVADVARTTTVLVVAHRLSTVTMADRIVVMDAGRVRAVGTHRELVTADPLYAELAATQFLATGG
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein SCO0742.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURB_PHOLL
Sequence: MLSLKEFNTFGLSAYAKRLDIAESAESLLALWQKAKSEKQPVLLLGGGSNVLFTTNFEGTVILNRIMGIQQRETDESWHLHVGAGENWHELVCHSLKNQIYGLENLALIPGCSGAAPIQNIGAYGIEFRDVCEYVDVLNLETGEQTRLSVGECQFRYRDSIFKHKYKANHSIISVGLLLKKNWQPILNYGNLTRLSKDNVTPQQIFDSVCAMRTSKLPDPAITGNAGSFFKNPIVSAEVAAKIKENYPDSPQYSYTNGMFKLAAAWLIERCNLKGYRIGGASVHLRQALVLINQENATGKDVVLLAAYIRRQVISKFGVLLEPEVRFIGSKGEIDAVECIS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_MYXXD
Sequence: MTSSSMTIAALATAPAAGAVGILRLSGPEALDVGRLLAPGVPAQPTPRHAYLASFVDAEGRSLDEGLFLYFRGPQSFTGEDVVELQAHGSPRLLRLLLTRALEDARVRHAAPGEFTRRAFLNGRLDLTRAEAVADLVAADSEAAVRAAAAGLSGALASRVQALEEPLRALHADMEGVLSFPDEAEGADEDVGERVTALRAQAETLLAEVGRGRLVRRGARVALFGPVNAGKSTLFNRLVGEARALVDDEPGTTRDALEARVEWDGLAVTLFDTAGLRETPGRVEALGIARTRALLTGVDLAVLVLPPGVTQAEVEAWTRDVGGTPVLVVDGKCDVAEVSSSPRQRVSGLTGEGVDALRDDMLGRLWGGGTPSAVALVSERHADALRRASEALGRAESASRVSTLEVVSGEVGLALEALGEVSGTVVSEALLDAIFQRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 41KD_LACHE
Sequence: MEVFFMRRYSATQINAELFWKFPKFLSINKKYVGLTNDDRMAYMLIKDRYRYSLSNNWIDKDKNVYVYFTIDDLKELLHVGKNKVTRIKQHLIDYGLLEIVKQGFDPQNKKNYPDRIYLLQPEYDPTDLISQSSHASALEQSGIPKMGTRYQNEGNLDNKGKSDSENCNKDTSALEQSGIPKMGANKDNNSSDTIKDTIKDTDQWNFSTNNYTPEQVTAQNQDLLSHLGETLTGDKEAPMFLNKDSINLIAKWFRTPEGASECISTILNAANDSRKNAESQIGHHELYFEDYNNELKRMITNRLRRYFNKMRTAKDGKIKNPKNYLYVSMRNMFDKWQNDVLMAEKDKANNKD
What are the official names of this protein?
41 kDa protein.
Protein: UPPP_NOVAD
Sequence: MDTIVTAILLGIVEGLTEFLPVSSTGHLILATELFGYDAHQWAMFNVVIQLGAILAVVVQYWRTFWAVGMGLLRLEPISLRFLRNLLAAFIPSAILGLALKKYIDVLLGSPSVVCWALIAGGIAILVIEKHAKQGEPSGIGQLPLRQAIGVGLAQCLAMVPGVSRSGATIMGALAMGIERRTAAEFSFFLAIPTMLGATTLELLDNRDALLGGTMGVGWSEIGVGFAVSFVVALAVIRLFVAYVSRAGFKPFAWYRIAAGAVALGWLAMR
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIN_SALAE
Sequence: MATIGYIRVSTIDQNIDLQRNALTSANCDRIFEDRISGKIANRPGLKRALKYVNKGDTLVVWKLDRLGRSVKNLVALISELHERGAHFHSLTDSIDTSSAMGRFFFHVMSAPAEMERELIVERTLAGLAAARAQGRLGGHPRAINRHEQEQISRLLEKGHPRQQLAIIFGIGVSTLYRYFPASRIKKRMN
What is the function of this protein?
A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB.  The orientation of the inversion region controls expression of fljB.  The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
What are the official names of this protein?
DNA-invertase.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: RLA2_TAESO
Sequence: MRYLAAYLLAQLGGTGRPQESDIKNILSSVGVECEQERAKLGVDQLHGKNVRDLINTGKEKMSAVSFGATPVAVPSGGAPAAATAAAEAPKGGDKAAAPPKEEKKEESEESDADMGFSPFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: RL18_STRZJ
Sequence: MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GEMI8_HUMAN
Sequence: MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSALLPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPLKF
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP.  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate.  Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP.
What are the official names of this protein?
Gem-associated protein 8, Gemin-8, Protein FAM51A1.
What are the subcellular locations of this protein?
Nucleus, gem. Cytoplasm. Note=Found in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm.
Protein: F16PC_ENTFA
Sequence: MATLNRDQQIEEIINLEAILNLPKGTEHFVSDLHGEFEAFDHILRNGSGRIREKVQFLFKQELNAHQMDELCFIIYYPEEKLTLLENESALSYEWWLLTIRRLVEIVRSSSMKYTRSKVRKALPETYGYILEELIYQYDETTTKNGYYQQIIEKIILLGEAKRFVTELAYLIQRLIIDHLHVIGDIYDRGPAPDKIMDRLMSYHSLDIQLGNHDMIWLAAYSGSLACLANVVRICARYGNLDLLEERYAIDLTALKKFSLETYKENPAFAPKKNPYRALTEAEKQVAMRVQQAIAIIQEKLEGQIIGRRPDFNLAHRLRLDKIQGETITFDECRYTLINSCFQTVSEEQPYQLTREEKQIIDDLLTQFQSSPRLTKHMRFLMEKASLYLVYNQNLLIHGCLPLNADGTFQAYTFKGHSYSGKALVDFFQEMLEEAYAQPASTDDYATDCLWYLWCGEGSSLFGKRAMKTFERYFLAEKETHYEEKNPYYSLRDTVEVCERILDEFEVTGENRHIINGHTPVKRTKGESPIKANGTLLVIDGGFSKSYQTITGIAGYTLLYNSFGLQLTAHKSFSSKETAILNNQDIHSIKQVIDRPLQRLLVKDTTIGKELLKQSQALQKQMKQNQ
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: MCRY_METTH
Sequence: MPMYEDRIDLYGADGKLLEEDVPLEAVSPLKNPTIANLVSDVKRSVAVNLAGIEGSLKKAALGGKSNFIPGREVELPIVENAEAIAEKVKRLVQTSEDDDTNIRLINNGQQILVQVPTTRMGVAADYTVSALVTGAAVVQAIIDEFDVDMFDANAVKTAVMGRYPQTVDFTGANLSTLLGPPVLLEGLGYGLRNIMANHVVAITRKNTLNASALSSILEQTAMFETGDAVGAFERMHLLGLAYQGLNANNLLFDLVKENSKGTVGTVIASLVERAIEDRVIKVASEMKSGYKMYEPADWALWNAYAATGLLAATIVNVGAARAAQGVASTVLYYNDILEYETGLPGVDFGRAMGTAVGFSFFSHSIYGGGGPGIFHGNHVVTRHSKGFALPCVAAAMCLDAGTQMFSVEKTSGLIGSVYSEIDYFREPIVNVAKGAAEIKDQL
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase II subunit beta, MCR II beta, Coenzyme-B sulfoethylthiotransferase beta.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase beta subunit family.
Protein: Y1543_XANOM
Sequence: MGRGPSIEGRKNASDAKRGKMFTKIIREISVAARAGGGDPSNNPRLRTAMDKGLSANMSKDVIERAIKKSTGELEGVEYEEVRYEGYAPGGVAVIVDCLTDNRVRTVADVRHAFSKCGGNMGTEGSVAFMFKRLGVLSFAAGIDEDTLTDAAIEAGADDVVVYPEDGAIDVLTAPDAFAQVRDALAAAGLEPAHAEIVFRADNDIAVDGDTAVQVRKLLDMLEDLDDVQDVYSNVDQAALGA
What are the official names of this protein?
Probable transcriptional regulatory protein XOO1543.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_BIGNA
Sequence: MKVKSSVRKICENCKVIRRSGKVIVICSNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DAPB_YERE8
Sequence: MTNSTIRIAVVGAGGRMGRQLIQAITQTKGVVLGAAVERAGSTLVGSDAGELAGTGLLNIAVSDDLSKVTDHFDVLIDFTRPEGTLEHLAICRAHHKAMVIGTTGFDDAGKAAISAASAEIGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHRYKVDAPSGTALAMGEAIAESLGRSLKDCAVYTREGHTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSRMTFANGAVKSAIWLSNHDNGLFDMRDVLSLNEL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI_KOCRD
Sequence: MSENSTPERVVLLDEQHQPTGTALKSEVHTEATPLHLAFSCHVLNPDGRVLVTRRALSKRTWPGVWSNSFCGHPGPHESFEDAIARRARQELGLEIRNLTVVVPEFQYRATDATGVVENEFCPVFVAVTDTDPQPAESEVAEYAWTAPRDLIAAVESAPYAFSPWLGDQVREPALREALG
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_ECO8A
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYH_BURTA
Sequence: MTEQKRKLEKLTGVKGMNDILPQDAGLWEFFEATVKSLLRAYGYQNIRTPIVEHTPLFTRGIGEVTDIVEKEMYSFVDALNGENLTLRPENTAAVVRAAIEHNMLYDGPKRLWYIGPMFRHERPQRGRYRQFHQVGVEALGFAGPDADAEIVMMCQRLWEDLGLTGIKLEINSLGLAEERAAHRVELIKYLEQHADKLDDDAQRRLYTNPLRVLDTKNPALQEIVRNAPKLIDFLGDVSRAHFEGLQRLLKANNVPFTINPRLVRGLDYYNLTVFEWVTDKLGAQGTVAAGGRYDPLIEQLGGKPTAACGWAMGIERILELLKEEHLVPEQEGVDVYVVHQGDAAREQAFIVAERLRDTGLDVILHCSADGAGASFKSQMKRADASGAAFAVIFGEDEVTNGTASVKPLRGTGDDGEKSVQQSVPVESLTEFLINAMVATAEDGDD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_STAAC
Sequence: MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEIFTELYREQQELDDIIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_STRA5
Sequence: MNIFDELKERGLVFQTTDEDALRKALEEGSVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDVERSLQTKKTVVSWGNKIRGQLSNFLEFETGDNKAVLVNNYDWFSNISFIDFLRDVGKYFTVNYMMSKESVKKRIETGISYTEFAYQIMQGYDFYELNKNYNVTLQIGGSDQWGNMTAGTELIRRKSNGVSHVMTVPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDADAVRFLKIFTFLSLKEIEDIRIQFEEAPHQRLAQKTLAREVVTLVHGEKAYKEAVNITEQLFAGNIKGLSVKELKQGLRGVPNYHVQTEDNLNIIDLLVTSGVVNSKRQAREDVSNGAIYINGDRIQDLEYTISENDKLENEITVIRRGKKKYFVLNFK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y043_OCEIH
Sequence: MDEQHYVYILRCRDQSLYTGYTNNLEHRLQMHETGKGAKYTRGRGPFEVLYVKKFINKSEAMQEEYRIKQLPRFEKLKLIEFQEQE
What are the official names of this protein?
UPF0213 protein OB0043.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: CM3C_CONRE
Sequence: CCAFPQWCGAGCIVPCC
What are the official names of this protein?
Conotoxin reg3c.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: E4PD_VIBPA
Sequence: MLKVAINGFGRIGRNVLRAVYESGKHQQIKVVAVNELAQPEAMAHLLQYDTSHGRFGKKISHDQEHLNVHHESGEYDAIRILHLSEIELLPWRDLEVDIVLDCTGVYGSKADGLAHIEAGAKKVLFSHPGANDLDNTIIYGVNHETLKDEHRVVSNGSCTTNCIVPIIKVLDEAFGIESGTITTIHSSMNDQQVIDAYHNDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVRVPTVNVTAMDLSVTINTNVKVNDVNQTIVNASQCTLRNIVDYTESPLVSIDFNHDPHSAIVDGTQTRVSNGQLVKMLVWCDNEWGFANRMLDTALAMKASSQVEL
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SACDR_HUMAN
Sequence: MVVVMKFFRWVRRAWQRIISWVFFWRQKIKPTISGHPDSKKHSLKKMEKTLQVVETLRLVELPKEAKPKLGESPELADPCVLAKTTEETEVELGQQGQSLLQLPRTAVKSVSTLMVSALQSGWQMCSWKSSVSSASVSSQVRTQSPLKTPEAELLWEVYLVLWAVRKHLRRLYRRQERHRRHHVRCHAAPRPNPAQSLKLDAQSPL
What is the function of this protein?
May play a role in acrosome formation and nucleus shaping during spermiogenesis.
What are the official names of this protein?
Sperm acrosome developmental regulator.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Detected in acrosome of round spermatids and spermatozoa.
Protein: ACSA_MYCBO
Sequence: MSESTPEVSSSYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWSEAPFAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAIPDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQCCYTMRTIFDVKPDSDVFWCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDVIGGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGYYFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTDETTTQAICAFVVLRANYAPHDRTAEELRTEVARVISPIARPRDVHVVPELPKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIRAAK
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HIRL1_ORYSJ
Sequence: MGNLFCCVQVDQSTVAIREQFGKFDAVLEPGCHCLPWFAGKRIAGHLTLRLQQLDVRCETKTKDNVFVNVVASIQYRALAGKANDAFYKLSNTRSQIQAYVFDVIRASVPKLNLDDAFEQKNDIAKAVEDELEKAMSAYGFEIVQTLIVDIEPDEHVKRAMNEINAAARLRVAANEKAEAEKIVQIKRAEGEAEAKYLSGLGIARQRQAIVDGLRDSVLGFSVNVPGTTAKDVMDMVLITQYFDTMKEIGASSKASSVFIPHGPGAVRDIATQIRDGLLQGQATTTSH
What is the function of this protein?
Positive regulator of hypersensitive response (HR)-like cell death.  May be involved in potassium ion channel regulation.
What are the official names of this protein?
Hypersensitive-induced response protein-like protein 1.