PharMolix/UniProtQA huggingface dataset:
Protein: FRBE_BLOB1
Sequence: MSLPNPFLIRPAPKKGKKGAPLVLLHDGGGTIFSYLQLGALGRDVYGIHNTRPGPTGVWEGGIAQMAAEYLDLIKTVVPSGPIIIGGWSLGGLVSFEMARQMAASAGSSSSSEQLQVLGLIMIDSRHPSTFTDKELVLPDSIKPAIRESIQHNMTQSRQLIRDYSTPSWPQGSQPPPTMFLRATRDLDGVPLPIQADAASSTRNGRMEGWREYEHDFIREVVEVEGTHFSIFEDQNIGELDKKLLAACKTLDRGVKS
What is the function of this protein?
Thioesterase; part of the gene cluster that mediates the biosynthesis of the antifungal antibiotic FR901469, an inhibitor of beta-1,3-glucansynthase, exerting antifungal activity against the pathogenes Candida albicans and Aspergillus fumigatus (PubMed:27660098).  FR901469 is a cyclic depsipeptide containing 12 amino acid residues and a fatty acid chain (PubMed:27660098).  The NRPS frbI contains 12 modules responsible for the formation of the depsipeptide backbone which is denoted as Acyl-Thr-Ala-Tyr-Val-4OHPro-Thr-Thr-3OHPro-threo3OHGln-Gly-Thr-Orn-OH (C71H116N14O23) (Probable).  The PKS frbB is probably involved in the production of the hydrocarbon chain, and the acyl-CoA ligase frbC might be involved in the transport of the chain to the peptide ptoduct of frbI (Probable).  Because FR901469 contains 3 hydroxylated amino acid residues, the 3 oxygenases frbA, frbH, and frbJ might be participating in amino acid hydroxylation (Probable).  As no thioesterase domains were detected in frbI or frbB, the thioesterases frbD and frbE may instead release and cyclize the products of the NRPS and PKS, respectively (Probable).
What are the official names of this protein?
Thioesterase frbE, FR901469 biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the AMT4 thioesterase family.
Protein: RRF_BRUA2
Sequence: MSDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISVPESRMLSVSVWDKSMVGAVERAIRDSGLGLNPITDGMTLRIPLPELNEQRRKELVKIAHQYAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEKVQKLTDDTIAEMDKIVAVKEGEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_CLOPE
Sequence: MNKLITVAIDGPAGAGKSTIAKIIGEKFNLMYINTGSMYRAVTLKALENNISAEEVDKLLVMIDGMDMHFENDELILNGENINSLITMPNISKNVSAYASIREVRERLVNLMRKMALKYSVIMDGRDIGTVVLKDANFKFFLTASPEERADRRYKELMGKGVEVNYDEILQDIIKRDYLDSNREVDPLRKAEDAIEIDTTGIGIMGVVEKISSYMEK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL1B_PHOVR
Sequence: MATVPEPTSEMMSYYYSDNENDLFFEADGPRKMKCCFQDLNNSSLKDEGIQLHISHQLQNKSLRHFVSVVVALEKLKKISLPCSQPLQDDDLKNVFCCIFEEEPIVCEVYDDDAFVCDAPLQSLDCKFRDKNQKSLVLYNSYELRALHLNGSSVNQQAVFRMSFLQGDENSNKIPVALCIKEKNLYLSCVMKDGKPTLQLEMLDPRVYPKKKMEKRFVFNKTEVKKILEFESSQFPNWYISTSKAEAMPVFLGNTKGGQDITDFTMEFSS
What is the function of this protein?
Potent pro-inflammatory cytokine.  Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.  Promotes Th17 differentiation of T-cells.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.  Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
What are the official names of this protein?
Interleukin-1 beta, IL-1 beta.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Secreted. Lysosome. Secreted, extracellular exosome. Note=The precursor is cytosolic. In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10.
Protein: UREG_MYCUA
Sequence: MAKHSHDHTHDHHDRPRRVRKPGEPLRIGVGGPVGSGKTALVAAICRQLRDELSLAVLTNDIYTTEDADFLRKHAVLPDSRIIAVQTGGCPHTAIRDDITANLDAIDDLIAAHDALDLILVESGGDNLTATFSSGLVDVQIFVIDVAGGDKVPRKGGPGVTFSDLLVVNKTDLAPLVGADLKVMARDAEAVRDGRPTVLQSLTEDPAATKVLDWVRSQLAAAG
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_SALPK
Sequence: MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQVIAESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANARGECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQSAQQRLGMAMDYYLANRSRRFTQIFHRLQQQHPQLRLARQQTALERLRQRMGFALEARIKQANQRQQRVSQRLSQQNPQPRIHRAQSRIQQLEYRLTENIRSRLSEQRERFGNAVTHLEAVSPLATLARGYTVSTTTDGKVLKKIKQVNAGDIMTTRLEDGWLESEVKSVTPGT
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTC2_MYCTO
Sequence: MVTEPLTKPALVAVDMRPARRGERLFKLAASAAGSTIVIAILLIAIFLLVRAVPSLRANHANFFTSTQFDTSDDEQLAFGVRDLFMVTALSSITALVLAVPVAVGIAVFLTHYAPRRLSRPFGAMVDLLAAVPSIIFGLWGIFVLAPKLEPIARFLNRNLGWLFLFKQGNVSLAGGGTIFTAGIVLSVMILPIVTSISREVFRQTPLIQIEAALALGATKWEVVRMTVLPYGRSGVVAASMLGLGRALGETVAVLVILRSAARPGTWSLFDGGYTFASKIASAASEFSEPLPTGAYISAGFALFVLTFLVNAAARAIAGGKVNG
What is the function of this protein?
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphate transport system permease protein PstC 2.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBE_SOLLC
Sequence: MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDPLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: KCY_MYCPU
Sequence: MTKNINIAIDGPSGVGKSTIAKKLADHLNYVFINTGLFYRAIAFYKDKFNLTQDLLVKELKNIKINYVNEDQIFLNNQDIAPYLRDEKISEQASEISTILDIRNFINQIIIDTMKVKKGYVIEGRDTTFKLAPDAEVRIFLDASSPIRARRRVLQNSQLNTESNYEKILDNINKRDYSDRNREVDPLHVAQGVIAIVNDHMNIEETFEKILGLVNEAIDKK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_MACMU
Sequence: MAHPVQLSLQDATSPVMEELITFHDHAFMAMSLISFLVLYALLSTLTTKLTNTSITDAQEMETIWTILPAIILILIALPSLRILYLTDEVNDPSFTIKSIGHQWYWTYEYTDYGGLIFNSYMLPPLFLNPGDLRLLEVDNRVVLPIEAPVRMMITSQDVLHSWTIPTLGLKTDAVPGRLNQTVFTATRPGVYYGQCSEICGANHSFMPIVAELIPLKIFEMGPVLTL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DRE2_THEAN
Sequence: MPKETLVVSKSEELAFEYFLSFNKFSSGSSSFLGQVTKASFFSSLASSGSKSSLNSLNNEFDHLSLYEIKNSSLETEKYKTILVVCDNTDEFYGEKGLSNLTLFHNSLLPNGKFVIAIPPNSSHEQEIKKEMMYSGLIDVVSSVYYFTTFITGVRPNWKSKTDKKSPSMIDAAPIDGYISKAPDYESCSTKPRACANCTCGRAEREKLNSTDLTSDVDAPTSSCGNCYLGDAFRCESCPYKGLPAFKPGEKVILD
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: RL14_CROS8
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVVRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CO9A1_MOUSE
Sequence: MKNFWKISVFFCVCSCLGPWVSATLKRRARFPANSISNGGSELCPKIRIGQDDLPGFDLISQFQIEKAASRRTIQRVVGSTALQVAYKLGSNVDFRIPTRHLYPSGLPEEYSFLTTFRMTGSTLEKHWNIWQIQDSAGREQVGVKINGQTKSVAFSYKGLDGSLQTAAFLNLPSLFDSRWHKLMIGVERTSATLFIDCIRIESLPIKPRGQIDADGFAVLGKLVDNPQVSVPFELQWMLIHCDPLRPRRETCHELPIRITTSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPPGDPGKPGAPGKPGTPGADGLTGPDGSPGSVGPRGQKGEPGVPGSRGFPGRGIPGPPGPPGTTGLPGELGRVGPIGDPGKRGPPGPPGPPGPSGTIGFHDGDPLCPNSCPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGPQGLRGITGIVGDKGEKGARGFDGEPGPQGIPGAAGDQGQRGPPGETGPKGDRGIQGSRGIPGSPGPKGDTGLPGVDGRDGIPGMPGTKGEAGKPGPPGDVGLQGLPGVPGIPGAKGVAGEKGNTGAPGKPGQLGSSGKPGQQGPPGEVGPRGPRGLPGSRGPVGPEGSPGIPGKLGSVGSPGLPGLPGPPGLPGMKGDRGVFGEPGPKGEQGASGEEGEAGARGDLGDMGQPGPKGSVGNPGEPGLRGPEGIRGLPGVEGPRGPPGPRGMQGEQGATGLPGIQGPPGRAPTDQHIKQVCMRVVQEHFVEMAASLKRPDTGASGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPKGLPGAIGLPGDPGPASYGKNGRDGEQGPPGVAGIPGVPGPPGPPGPPGFCEPASCTLQSGQRAFSKGPDK
What is the function of this protein?
Structural component of hyaline cartilage and vitreous of the eye.
What are the official names of this protein?
Collagen alpha-1(IX) chain.
What is the protein family that this protein belongs to?
Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: NXT1_DROME
Sequence: MDSDLKAKVESCARTADTFTRLYYASVDNRRQQIGRLYLDNATLSWNGNGAIGRQMIESYFQELPSSNHQLNTLDAQPIVDQAVSNQLAYLIMASGSVKFADQQLRKFQQTFIVTAENDKWKVVSDCYRMQEV
What is the function of this protein?
Stimulator of protein export for NES-containing proteins (By similarity).  Plays a role in the nuclear export of mRNA (PubMed:14729961).  Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA (By similarity).  In ovaries, plays a role in transposable element silencing regulation (PubMed:31219034, PubMed:31368590, PubMed:31384064, PubMed:31570835, PubMed:33856346).  Forms a complex with nxf2, Panx and piwi which acts as effector of cotranscriptional transposon silencing (PubMed:31219034, PubMed:31368590, PubMed:31384064, PubMed:31570835).  In ovarian follicle cells, enables the nuclear export of flamenco (flam) transcripts and subsequent piRNA biogenesis (PubMed:33856346).
What are the official names of this protein?
NTF2-related export protein, p15.
What are the subcellular locations of this protein?
Nucleus. Nucleus envelope. Note=Associates with the nuclear pore complex.
Protein: RS2_LACGA
Sequence: MTVVTMKQLLEAGVHFGHQTRRWDPKMAPYIFTQRNGIYIIDLQKTIRMLDDAYNYVKAVAQDGGVFLFVGTKKQAQDAVKEEATRAGQYYVNQRWLGGTLTNWTTIQSRVKRLKQLKEMSEDGTFDVLPKKEVALLTKEMEKLERFLGGIEDMPRIPDVMFVVDPKKEKIAVHEANILGIPVVAMVDTNTDPDPIDVVIPANDDAIRAIRLISGAMADAIIEGKQGQDDSEDVEKEMADKAAAENDDEESIEEVVEKSED
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SYE_SHEDO
Sequence: MTTPAITKTRFAPSPTGFLHVGGARTALYSWLQARANNGEFVLRIEDTDIERSTQAACDAILDGMNWLGLTWDEGPYYQTKRFDRYHEIIGQMLEKGTAYKCYCSRERIETMREEQAAAGLQQKYDGHCRNLAARETNEPFVIRFKNPLEGSVVFDDHVRGRIEISNEMLDDLIIQRTDGVPTYNFCVVVDDWDMGITSVVRGEDHINNTPRQINILKALGAPIPEYAHVSMILGDDGAKLSKRHGAVGVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFSMEEMKQHFKLGDINKAASAFNTDKLIWLNQHYIKTLDPEYVASHLAWHMEDQNIDTSNGPALAEIVTALSERAKTLKELAESSRYFFEDFTDFDEVQAKKHLRGVALEPLTLVKTKLAALTEWSVSVIHQVIEDTATELEVGMGKVGMPLRVAVTGAGQSPALDLTLFLIGKDRSEQRISKAIDFVADRINS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBB_AGRFC
Sequence: MTARAIIIGAPRSGSGKTSVTIGLLRAFARRGVKVRGIKTGPDYIDPGFHAFATGTPGLNLDSWAMQPDLLRHLFSQQTEDAELILIESAMGLFDGIPVAENRTGSAADLARLFRIPVLLVLDVSGQSQTAATIAHGFAHYDPDVTMGAVVLNRAGSERHRTLCTEAIEKIGLPVVGCVLRDPSLILPERHLGLVQASEHPEIDPHIDRLADAMEKSIDLDTLFSLAAPVDMPCGSVAAAIAPPGQRIALAEDAAFTFLYPHLRRHWRAAGAEIVPFSPLADEAPDESCDICWLPGGYPELFAGKLADAVGFKAGITRFAETKPVHGECGGYMVLGERLEDAEGVIHAMTGLLSHATSFATRKMNLGYRQATIAADSPLGMAGDVLRGHEFHYARVIDPGRDQPFAHMADGQGRPLGPSGGRRGFVSGTFFHAIAKGG
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Hydrogenobyrinate a,c-diamide synthase, Hydrogenobyrinic acid a,c-diamide synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: FOLD_MYCA1
Sequence: MGAITLDGKATRDEIFVDLKQRVAALTAAGRTPGLGTILVGDDPGSQAYVRGKHADCAKVGITSIRRDLPADISTAALNDTIDELNANPECTGYIVQLPLPKQLDENAALERVDPDKDADGLHPTNLGRLVLNNPAPLPCTPRGIVHLLRRYDVEIAGAHVVVIGRGVTVGRPLGLLLTRRSENATVTLCHTGTRDLPALTRQADIVVAAVGVPHLLTADMVRPGAAVLDVGVSRVDGKLAGDVHPDVWEVAGHVSPNPGGVGPLTRAFLLTNVVELAERE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MURQ_SALDC
Sequence: MNLGTLVSETRNPQTMDLDALPTPELVKRFNEQDTRVAEAVKATLPDVARAVDAAVAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAETLLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: ATPB_CLAMS
Sequence: MTDTATRPVASDSVAGVGRIVRVTGPVVDIEFPHDSIPPVYNALKTTITIGEDSTEITLEIALHLGDDVVRAIALKPTDGLVRGQEVRDTGAAISVPVGDITKGKVFNVTGDILNNEGGEPIEITERWPIHRKPPMFDQLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGAGVGKTVLIQEMIQRVAQDHGGVSVFAGVGERTREGNDLIMEMEEAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFRDVKNQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPNLADEMGVLQERITSTRGHSITSLQAIYVPADDYTDPAPATTFAHLDATTELSREIASRGLYPAVDPLTSTSRILDPRYLGQAHYDTATRVKAILQKNKELQEIIAILGVDELSEEDKVTVSRARRIQQFLSQNTYMAKKFTGVEGSTVPLKNTIESFSKIADGDYDHVAEQAFFNVGDLDDVERRWSEIQKENG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FABA_BRADU
Sequence: MLNRRNGYEYEDLLACARGEMFGPGNAQLPLPPMLMFDRITDINDNGGEFGKGLVRAELDVKPDLWFFGCHFKNDPVMPGCLGLDALWQMVGFYLGWSGGEGRGRALGLNELKFSGQVLPEARKVVYNVDIKRVMRAKLVLGIADGWLSVDDQIIYRAKDLKVGLFKQGTSLG
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_NITMU
Sequence: MIQMQSILQVADNTGARSLMCIKVLGGSKRRYAGIGDIIKVSVKDVAPRGRVKKGEVYNAVVVRTSKGVRRADGSLIKFDGNAAVLLNAKLEPIGTRIFGPVTRELRTARFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RIMP_RHORT
Sequence: MALWGWRGVGRRPTFFVFASLAPIGRDFLRRNGDDARMMGHLEKLLAPTLDAMGYEVVRVTLLGSQNPTLQVMAERLDGVAMTVSDCETISRALGALLDVEDPIAGRYSLEISSPGIDRPLTRPKDYARFAGHEARIETDRLIEGHRRMKGLLLGIDEDRTVRLRLIEGKAAEDGTLPEVEIPFGAIVKAKLLLTDALIAKALKDAEALADEGEAAGGAVEGGVA
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_BARVE
Sequence: MIIRSPEPEVKILVDRDPIKTSFEEWAKPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYSEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGIKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIIVAHHMYSMPPYPYLATDYATQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTNRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGVTAPGETASTSLTWGGGELVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIVQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.