PharMolix/UniProtQA huggingface dataset:
Protein: ACM3_CHICK
Sequence: MLTHYQLCFQKRSSQNYTVPDPTSCFDVPPWTILCQRATMIMHNNSSALPLFSNVSSFWKRDSHGPGLLDEGASLIGSYDSPETTESFPFSTVETTNSSLNATIKDPLGGHAVWQVVLIAFLTGIIALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMGHWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWIISFVLWAPAILFWQYFVGKRTVPLDECFIQFLSEPIITFGTAIAAFYLPVTIMSILYWRIYKETEKRTKELAGLQASGSEAETARFVHQTGSSRSLSSYELQRQSTKRSSRRKYRRCHFWLTMKSWEPNTDQGDQEHSSSDSWNNNDAAASLENSASSDEEDITAETRAIYSIVLKLPGHSAILNSTKLPSSEDLNESADELQKSDTDSQEKKPKKLQPPKSIQDGGSFQKSFSKLPIQPGSAETATASDGISSVTKTSAALPLSFKEATLAKKFALKTRSQITKRKRMSLIKEKKAAQTLSAILFAFIITWTPYNIMVLVNTFCDCVPKTVWNLGYWLCYINSTVNPVCYALCNKMFRNTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRIPREAS
What is the function of this protein?
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.  Primary transducing effect is Pi turnover.
What are the official names of this protein?
Muscarinic acetylcholine receptor M3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: SWET5_ORYSJ
Sequence: MVMNPDAVRNVVGIIGNLISFGLFLSPLPTFVTIVKKKDVEEFVPDPYLATFLNCALWVFYGLPFIHPNSILVVTINGTGLLIEIAYLAIYFAYAPKPKRCRMLGVLTVELVFLAAVAAGVLLGAHTYDKRSLIVGTLCVFFGTLMYAAPLTIMKQVIATKSVEYMPFTLSLVSFINGICWTIYAFIRFDILITIPNGMGTLLGAAQLILYFCYYDGSTAKNKGALELPKDGDSSAV
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane (By similarity).  Can transport galactose.  Prevents growth but promotes senescence (PubMed:25988582, PubMed:24709840).  Involved in regulating the crosstalk between sugar and auxin.  Regulates negatively the auxin signaling pathway and translocation (PubMed:24709840).
What are the official names of this protein?
Bidirectional sugar transporter SWEET5, OsSWEET5.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URE2_LYSSC
Sequence: MIPGEIRPKKGVIEINVGRATKKVLVANTGDRPIQVGSHFHFIEVNRFLEFNREDAIGMHLNIPSGTAVRFEPGEEKEVELVEFGGKQHVFGLNKLTEGSTHHKDEILDKAIEGGFKGAEEK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_CUPPJ
Sequence: MQLVIVAVGHKMPGWIETGFNEYAKRMPPELRIELREVKPETRSSSNNAATVMQREAARIDAVLGSLSRQCRIVALDERGRDFTTVQLAGQLTDWQREGGDVAFLIGGADGLDPALKARAQTLLRLSSLTLPHGMVRVLLAEQLYRAWSVTQNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_STRZP
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLTNWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVMYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLADAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NIP2_ARATH
Sequence: MASSSSSSYRFQSGSYPLSSSPSLGNFVERIKDACHFLVSAVLGTIISAILTFFFALVGTLLGALTGALIGQETESGFIRGAAIGAISGAVFSIEVFESSLDLWKSDESGFGCFLYLIDVIVSLLSGRLVRERIGPAMLSAVQSQMGAVDTAFDDHTSLFDTGGSKGLTGDLVEKIPKMTITGNNNTDASENTDSCSVCLQDFQLGETVRSLPHCHHMFHLPCIDNWLLRHGSCPMCRRDI
What is the function of this protein?
Intrinsic thylakoid membrane protein that fixes RPOT2 on the stromal side of the thylakoid membrane.
What are the official names of this protein?
NEP1-interacting protein 2, RING-H2 finger protein ATL25.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. NIP subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ODPB_YEAST
Sequence: MFSRLPTSLARNVARRAPTSFVRPSAAAAALRFSSTKTMTVREALNSAMAEELDRDDDVFLIGEEVAQYNGAYKVSKGLLDRFGERRVVDTPITEYGFTGLAVGAALKGLKPIVEFMSFNFSMQAIDHVVNSAAKTHYMSGGTQKCQMVFRGPNGAAVGVGAQHSQDFSPWYGSIPGLKVLVPYSAEDARGLLKAAIRDPNPVVFLENELLYGESFEISEEALSPEFTLPYKAKIEREGTDISIVTYTRNVQFSLEAAEILQKKYGVSAEVINLRSIRPLDTEAIIKTVKKTNHLITVESTFPSFGVGAEIVAQVMESEAFDYLDAPIQRVTGADVPTPYAKELEDFAFPDTPTIVKAVKEVLSIE
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial, Pyruvate dehydrogenase complex component E1 beta, PDHE1-B.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SODF_ANASL
Sequence: AFVQEPLPY
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: VPR_HV1AN
Sequence: MEQAPENQGPAKEPFNEWALELLEELKAEAVRHFPRPWLHALGQYIYETYGDTWVGVMAIIRILQQLLFTHYRIGCQHSRIGINPRGRGRRNGSSRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: H2B1_SOLLC
Sequence: MAPKAGKKPAEKKPVEEKKAEEVPAEKKPKAGKKLPKDAGADKKKKKSKKSVETYKIYIFKVLKQVHPDIGISSKSMGIMNSFINDIFEKLAQESSRLARINKKPTITSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSN
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.1, LeH2B-1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DIVIB_AERUA
Sequence: MVDWDKEAQRFRQRRQEAEKQEELASSEGQADEPSDDPGLSQALPQKHLGLEDKQQGLPNEEEAKGEDFAKDQEQKHKKTFNHRKYINWTYLSRSKNKKLQLKSVSWSRLILAAAFLFMIIFSAFWLSPLNRIATIEVSGNNIVPQEQILYGSGLRENMTYLGIESKTGVVDNRLKQLFPSVRSVQLNAKGNRTVEVNVQEFRAIGYVKKQDFYYPVLENHIMLDGAIPYLDQDIPLFTGFEDQELLHLANQLSKLSDDLLAKINEVVNISDDNYPNHIALKMEDGNIVVGFIDSIADRMQYYDQIVSELEGKTGVINMEVGSYFQEKNPLNDPFASPEEKASYQEKVDQAKEKSKEKQAKADKHSSESKLGDKPKPRGEQSGASEEVTSSQRQTSSQSSPRPGTNSSQQSSTVTQTRSSNS
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: ZN574_BOVIN
Sequence: MTEESEETVLYIEHRYVCSECNQLYGSLEEVLMHQNSHVPQQHFELVGVADPGVTVAAEAASGTGLYQTLVQESQYQCLECGQLLMSPSQLLEHQELHLKMMAPQEAVPAEPPPKAPALSSSTIHYECVDCKALFASQELWLNHRQTHLRATPTKPPTPVVLGSPVVVGSPVGQTRVAVEHSYRKAEEGGEGAAVPSAAATTTEVVTEVELLLYKCSECSQLFQLPADFLEHQATHFPAPAPESEEPVLQQETLTPAPVEVPVSQPEPVPSSDHSYELRNGEALGRDRRGRRARRNNSGEPGGAATQELFCSACDQLFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCPCGKTFVNLTKFLYHRRTHGVGGVPLPTTPVPPEEPVLGFPEPAPAETGEPEAPEPPVAEESSAEPAAPGTYRCLLCSREFGKALQLTRHQRFVHRLERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRLVHAQHFPYRCQECGVRFHRPYRLLMHRYHHTGEYPYKCRECPRSFLLRRLLEVHQLVAHAGRQPHRCSSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAKEPPAPRAPRAARTPITSPTTLGSAAPAAPAAPARRRGLECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEAEAAVGLAVMETAVEALPLVEAIEIYPLAEAEGVQISG
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 574.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EA92_VICFA
Sequence: MEFAHLTVLSLFCLAFVGITATSSEEDYWQSIWPNTPLPKTFSDLLIPSGKTNSLPIKSEELKQYSTLFFEHDLHPRKNFILGNTNSVGSIIRPFTKSRQGVTDSIWLANKEKQSFEDFCYSPTAIAEHKHCVSSLKSMIDQVISHFGSTKIKAISSNFAPYQDQYVVEDVKKVGDNAVMCHRLNFEKVVFNCHQVRETTAYVVSLVASDGTKTKALTVCHHDTRGMNPELLYEALEVTPGTVPVCHFIGNKAAAWVPNHTADNLCVM
What are the official names of this protein?
Embryonic abundant protein USP92.
Protein: DRE2_MEDTR
Sequence: MDAAKMYGAVLACTDEAVLPVSQVFDAIRELGNEGVEKLDPLVITSASSLSKFPVESSSVDLVVLIWKSLDFPIDQLTQEVLRVLKAGGTTLIRKSSQSAVGSGDKMIPDLENKLLLAGFSEIQALQSSVIKAKKPSWKIGSSFALKKVVKSSPKVQIDFDSDLIDENSLLSEEDLKKPELPSGDCEIGPTRKACKNCSCGRAEEEEKVLKLGLTAEQINNPQSACGSCGLGDAFRCSTCPYKGLPAFKMGEKVALSGNFLAADI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: PERR_STAES
Sequence: MSAELESIDHELEESIASLRKAGVRITPQRQAIMRYLISSHSHPTADEIYQALSPKFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEKCGKIVDFHYPQLDEVEQLAQHVTDFDVTHHRMEIYGVCKECKEEGN
What is the function of this protein?
Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins.  May act as a hydrogen peroxide and organic hydroperoxide sensor (By similarity).
What are the official names of this protein?
Peroxide-responsive repressor PerR.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC18_MOUSE
Sequence: MAKGGKGPKGKKITLNVAKNCIKITFDGRKRLDLSKMGITTFPKCILRLSDIDELDLSRNMIRKIPDSIAKFQNLRWLDLHSNYIDKLPESIGQMTSLLFLNVSNNRLTTNGLPVELNQLKNIRTVNLGLNHLDSVPTTLGALKELHEVGLHDNLLTTIPASIAKLPKLKKLNIKRNPFPNADESEMFVDSIKRLENLYLVEEKDMCSSCLQRCQQARDKLNKIKSMAPSAPRKALFSNLVSPNSTAKDAQEEWRLRSPSTF
What is the function of this protein?
May be involved in the regulation of spermatogenesis and sperm maturation.
What are the official names of this protein?
Leucine-rich repeat-containing protein 18, Testis-specific LRR protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHC_JONDD
Sequence: MITWPAPQVPSIPGALTSVRVMDTSSGQLVETVRPGVGESSMYVCGITPYDATHIGHAATYIAFDLLYRAWLDAGQRVVYTSNVTDVDDPLLERATATGVDWTELATSQITLFFDDMSALGVLPPHTYLSAVESVPMVISATRHLLESGRAYRVPVPAQERPVHSPAYDIYADVTSDPDFGSISGYTSEERVRLFTDRGGDPATPGKKNPIDPIMWKAQREGEPGWDGDDLGWGRPGWHIECTTIAHCGIGRSCTVQGGGSDLIFPHHEMSSAHARALFGQDAGASVHAHAGLIAYQGEKMSKSKGNLVFVSRLRQEGVDPMAIRLAILANHYRDEWEWTSDVLDAGIKRHQLWLQAMSTNGGPHPGATLAAMREALSNDLDAPRALDAVDAWAYATLAGNDEDPGAPGVVSRAVNALLGIRL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: Y196_THEAC
Sequence: MQFSVGNIYQPSECHTCMDDQTFISTIKTGDKKKIEEMADDLWNYRDLYQRNALMISAMYGRTDLIEFFAARYDHIDDRDIEGNTALMWAVRNNRMESAKSLIALKCSIDIPDSAGNTPICWAVIFGYTDMVKLLISSGANINISNDEGDTPAILASKYGRSECLKMLIEAGCDLNAKNHNAQNVWKAAEAFGRKEILEVLASLSNGR
What are the official names of this protein?
Putative ankyrin repeat protein Ta0196.
Protein: PISD_CRIGR
Sequence: MAASVCRPYVRSLPGVMPWRSSSCHYEYTAMHHFLGSFQKLPFEPFNTGARKIHTAPVRSLFLLRPVPILLATGGGYAGYRQYEKYRDQKLEKLGLEIPPKLASHWEVALYKSVPTRLLSRAWGRLNQVELPYWLRRPVYSLYIWTFGVNMTEAAVEDLHHYRNLSEFFRRKLKPQARPVCGLHSVISPSDGKILTFGQVKNCEVEQVKGVTYSLESFLGPRTYTEDLSFPPASSRDSFRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFCHNERVVLSGDWKHGFFSLTAVGATNVGSIRIYFDQDLHTNSPRYSKGSYNDLSFVTHANKEGIPMRKGEHLGEFNLGSTIVLIFEAPKDFNFRLKAGQKIRFGEALGSL
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).  Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.  May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane (By similarity).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
[Phosphatidylserine decarboxylase beta chain]: Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side. SUBCELLULAR LOCATION: [Phosphatidylserine decarboxylase alpha chain]: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.
Protein: DTD_STRZJ
Sequence: MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCO89_SCHPO
Sequence: MERPSLSRRTSSSTVSTDGEGVYSRSTKERKRNFIVNSRLKRGGGHVRVNRSGRLGSVTMRPSALTRAHSQNPNSSLVNNSSAVSHLTKQRSLNDLHELNGPKHVAKNGLIPLTQRKPNCVWDDAPVDNDSTAGNLDSDSALPTPSVTTNEAADSSRASSPVTRVVAVHDNKKKIINSNISNAPPFNNTDVQASARPPAAGQDDSAADASTTKSSPVHNEVMAEPLPHSNNREVTQATNQPKWQIHSGSDIASEPPTLSRGNSLSLLANRKVPSTNVKKSQAELYDLGSSTSRTQQKLLIQRASSKFDIVEDDMDTNPSKRFSNPHTKHIMDLVRTQYRNVLRTRELIPEFLEKIRSSYSNNQNFDSQNAFNTSAAGTAGTREETISNGQNGIVASAETSKKDDGVQSASLNASMSARSHARQRSIHVPKTRKDTDYESIHQKLLQLWSQG
What is the function of this protein?
Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals.  Tor2 is essential for growth.  Nutrient limitation and environmental stress signals cause inactivation of TORC1.  Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression.  TORC1 negatively controls G1 cell-cycle arrest, sexual development and amino acid uptake.  Represses mating, meiosis and sporulation efficiency by interfering with the functions of the transcription factor ste11 and the meiosis-promoting RNA-binding protein mei2.
What are the official names of this protein?
Target of rapamycin complex 1 subunit tco89, TORC1 subunit tco89.
What is the protein family that this protein belongs to?
Belongs to the TORC subunit TCO89 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at the barrier septum.
Protein: SSB1_KLUMA
Sequence: MAEGVFPGAIGIDLGTTYSCVATYENSVEIIANEQGNRVTPSFVAFTPEERLIGDAAKNQAALNPKNTVFDAKRLIGRRFDEESVQSDMKTWPFKVIDSNGAPLIEVEYLGETKTFSPQEISSMVLTKMKEIAEAKIGKKVEKAVVTVPAYFNDAQRQATKDAGAIAGLNVLRIINEPTAAAIAYGVGAGNSEKERHVLIFDLGGGTFDVSLLHIAGGVYTVKSTSGNTHLGGQDFDTNLLEHFKTEFKKKTGADISGDARALRRLRTAAERAKRTLSSVAQTTVEVDSLFDGEDFEATITRARFEDINAALFKSTLEPVEQVLKDAKISKSQIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDLLLLDVAPLSLGVGMAGDVFGVVVPRNTTVPTIKRRTFTTVADHQTTVTFPVYQGERVNCKENTLLGEFDLKGVPPMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSANITISNAIGRLSSEEIEQMVNQAEEFKAADEAFAKKHEARQRLESYISSVQQTVTDPVLSAKIKRNAKAKVEAALADAFSTLQIEDASADDLRKAEVGLKRAVTKAMSTR
What is the function of this protein?
Ribosome-bound, Hsp70-type chaperone that assists in the cotranslational folding of newly synthesized proteins in the cytosol.  Stimulates folding by interacting with nascent chains, binding to short, largely hydrophobic sequences exposed by unfolded proteins, thereby stabilizing longer, more slowly translated, and aggregation-prone nascent polypeptides and domains that cannot fold stably until fully synthesized.  The Hsp70-protein substrate interaction depends on ATP-binding and on allosteric regulation between the NBD and the SBD.  The ATP-bound state is characterized by a fast exchange rate of substrate (low affinity state), while in the ADP-bound state exchange is much slower (high affinity state).  During the Hsp70 cycle, the chaperone switches between the ATP-bound state (open conformation) and the ADP-bound state (closed conformation) by major conformational rearrangements involving mainly the lid domain.  Ssb cooperates with a specific Hsp40/Hsp70 co-chaperone termed the ribosome-associated complex (RAC), which stimulates the ATPase activity of the ribosome-associated pool of Ssbs and switches it to the high affinity substrate binding state.  Hsp110 chaperone SSE1 and FES1 act as nucleotide exchange factors that cause substrate release.
What are the official names of this protein?
Ribosome-associated molecular chaperone SSB1, Heat shock protein SSB1, Hsp70 chaperone Ssb.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family. Ssb-type Hsp70 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with translating ribosomes.
Protein: H13A6_CYRHA
Sequence: MKTAIFTVVLALAVFAVLSFGWEANEKALSEEFTELIHEKEAASEAEARECRYFWGECHDHMPCCDWLVCRYKWPITYNICVWNRTFPEK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U7-theraphotoxin-Hhn1a 6, U7-TRTX-Hhn1a, Hainantoxin-XIII.6, HNTX-XIII.6.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 13 (Hntx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMFO_STRT1
Sequence: MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREGYAEAVTAEIESHPLIEVIREEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFYDAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQSKSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTHAESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_ECO5E
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLEIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: YBJL_ECO8A
Sequence: MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVIGLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLMVFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNPA_OCEIH
Sequence: MKKQYRIKQNEEFQYTFKKGHSFANRQLVIYYREKEDQCHFRIGLSVGKKIGNAVMRNRIKRCLRQSFHELEPDIKPAYDIVIIARNPTRNMNCGEIKKSLSHLLYKEGLLKNTRNKTSLR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.