PharMolix/UniProtQA huggingface dataset:
Protein: SYM_METM5
Sequence: MKHLVTTALAYTNGPLHLGHARSTYIPADIYTRYLRLKGEEVIHVGGTDNHGVPITLTAEREGVKPIDIVDRYHNAIKADLDSLNVSFDTFGRTHSDIHIETAQEFYSKLKENGYIYEKEIEQFYCEKCDMYLADRYVEGICPFCEGEARGDHCEVCGRHLEPTELVNPYCIHCNSKPEIKRTTHYFFKLSAMQDVLKEYIENSPEMPEHVKNMALRWIEELHDWDVSRNIKWGVPIPGCDDQVMYVWIEAPIGYVSFTKQLGDLWKDYWLENTGDSKISHFIGKDITVHHAVFWPGILKGIGGYKMPNAVVSGGYLTLENKKMSTSKNWVVWVKDFIENFSSDYLRYFFMINAPLNRDTDFSWDDFQKRINTELIDIIGNFTHRTLVFTERKFGSTPVVDLNQLKDEDKKLISKCEDTLNRVDSLIREYNFKDALMEIIHLAKEGNGYFQGMAPWAIKDEERLKEVMYTCSVALKYIVYLLSSFMPEKTALLLEYMNEELDLEVRGNPLKKPKVIFTKVSDEDISRMKENLMKATKKAETKSDEKSKKVKSGEKMDIIDIDYFGNIDLRVGQILEVEEVPRSKKLYKITADLGDEKRQIVSGLKGAYEAEELVGKKVIIICNLKPAKLCGVESQGMLLAAEDDSIVSLLALDRDLPVGSKIH
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH_HRSS2
Sequence: MENTSITIEFSSKFWPYFTLIHMITTIISLLIIISIMIAILNKLCEYNVFHNKTFELPRARVNT
What is the function of this protein?
Viroporin that forms a homopentameric ion channel displaying low ion selectivity.  May play a role in virus morphogenesis and pathogenicity at various stages of the viral life cycle.  Accumulates at the membrane of the Golgi apparatus in infected cells and may facilitate virus release by modifying the secretory pathway.  May enhance host membrane permeability and disrupt cellular ion homeostasis, which can be sensed as damage-associated molecular patterns/danger signals, triggering NLRP3 inflammasome activation and inflammatory immune response.  Also inhibits host TNFA-mediated signaling pathway and may delay apoptosis, allowing time for the virus to replicate.
What are the official names of this protein?
Small hydrophobic protein, Small protein 1A.
What is the protein family that this protein belongs to?
Belongs to the orthopneumovirus small hydrophobic protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. Host Golgi apparatus membrane; Single-pass type II membrane protein. Host endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Present in very small amount in the virion. Detected in lipid rafts of host Golgi apparatus membrane.
Protein: FPG_RHOJR
Sequence: MPELPEVEVVRRGLERHIVGASIDSVDILHPRAIRRHLPGAADLAGQLTGERIASADRRGKYLWLVLEPSTVALVVHLGMSGQMLVQPPELPTEKHLRIRARLDSGLDLRFVDQRTFGGWALAPLVDVDGSLVPDSVAHIARDPLDPRFDLAATVKVVRGKHTEVKRALLDQTVVSGIGNIYADEALWRARIHGNRLTDRLSGPKVREVLTAAQEVMREALTQGGTSFDALYVNVNGESGYFDRSLSAYGQEDRPCPRCGTAIRREKFMNRSSFSCPKCQPAPRRSLAKSSV
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: VPC29_MYCTU
Sequence: MTVLLDANVLIALVVAEHVHHDAAADWLMASDTGFATCPMTQGSLVRFLVRSGQSAAAARDVVSAVQCTSRHEFWPDALSFAGVEVAGVVGHRQVTDAYLAQLARSHDGQLATLDSGLAHLHGDVAVLIPTTT
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its cognate antitoxin is VapB29 (By similarity).  Has ribonuclease activity.
What are the official names of this protein?
Ribonuclease VapC29, RNase VapC29, Toxin VapC29.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: TATA_ACIBS
Sequence: MAGLSIWHVVIFAIVVILLFGTSKLKNIGKDVGGAVRDFKKSVREEDEAASLNSPRTIDAQAKTSESTSVKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRBM_SAISC
Sequence: MLGVLVLGALALAGLGFPAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISLLLNGDGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNGAPLCGPLCVAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITYGTPFAARGADFQALPVGSSAAVAPLGLQLMCTAPPGAVQGHWAREAPGAWDCSVENGGCEHACNAIPGAPRCQCPAGAALQADGRSCTASATQSCNDLCEHFCVPNPDQPGSYSCMCETGYRLAADQHRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDLVDGECVEPVDPCFRANCEYQCQPLNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTACPADCDPNTQASCECPEGYILDDGFICTDIDECENGGFCSGVCHNLPGTFECICGPDSALARHIGTDCDSGKVDGGDSGSGEPPPSPTPGSTLTPPAVGLVHSGLLIGISIASLCLVVALLALLCHLRKKQGAARAKMEYKCAAPSKEVVLQHVRTERTPQRL
What is the function of this protein?
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin.  This complex is responsible for the conversion of protein C to the activated protein C (protein Ca).  Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated (By similarity).
What are the official names of this protein?
Thrombomodulin, TM.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: COAD_BRUC2
Sequence: MTIAIYAGSFDPVTNGHIDVLKGALRLADQVIVAIGMHPGKKPLFSFDERVALIEVSAKAVLHKDAARVSVIAFDGLVIDAARKHGAQLMVRGLRDGTDLDYEMQMAGMNGTMAPELQTVFLPADPAVRTITATLVRQIASMGGDIKPFVPVAVAAALNTKFKS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDM5_ARATH
Sequence: MDNSSDEESEISESEIDVYYEKPYEKLMNGDYKVKVKDTFRCPFCAGKKKQHYKYKELLAHASGVAKGSASRSAKQKANHFALAKYMENELAGDADVPRPQIPSSSTEQSQAVVDDIYVWPWMGIVINPVRRTDNKNVLLDSAYWLKKLARFNPLEVKTLWLDQESVVAVIPQFNSGWSGFKSVTELEKEYEIRGCGRKDWIDKRGDWRSKAYGWCARADDYNSQGSIAEYLSKVGKLRSFSDITKEEIQNKSIVVDDLANKIAMTNEDLNKLQYMNNEKTLSLRRVLIEKDELDRVYKQETKKMQELSREKINRIFREKERLTNELEAKMNNLKIWSKQLDKKQALTELERQKLDEDKKKSDVMNSSLQLASLEQKKTDDRVLRLVDEHKRKKEETLNKILQLEKELDSKQKLQMEIQELKGKLKVMKHEDEDDEGIKKKMKKMKEELEEKCSELQDLEDTNSALMVKERKSNDEIVEARKFLITELRELVSDRNIIRVKRMGELEEKPFMTACRQRCTVEEEAQVQYAMLCSKWQEKVKDSAWQPFKHVGTGDRKKEVVDEEDEEIKKLREEWGEEVKNAVKTALEELNEFNPSGRYSVPELWNSKQGRKATLKEVIDYITQQVKTLKRRRA
What is the function of this protein?
Acts in association with FDM3 and FDM4 for RNA-directed DNA methylation (RdDM).
What are the official names of this protein?
Factor of DNA methylation 5.
Protein: RRP3_CYAP4
Sequence: MPVQTILEVSLSQFILKVLWLDSNVALAVDQVVGKGTSPLTSYFFWPRADAWEQLKTELEKKTWISEADRIALLNRATDIINYWQEEGRNRPLAEAQSRFPDITFVGTA
What is the function of this protein?
Probably a ribosomal protein or a ribosome-associated protein.
What are the official names of this protein?
Probable 30S ribosomal protein PSRP-3, Ycf65-like protein.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cS23 family.
Protein: RNS5_PYRPY
Sequence: MGITGMVYVVTMVFLLIVLILSSSTVGYDYFQFTQQYQLAVCNSNRTPCKDPPDKLFTVHGLWPSSMAGPDPSNCPIRNIRKREKLLEPQLAIIWPNVFDRTKNKLFWDKEWMKHGTCGYPTIDNENHYFETVIKMYISKKQNVSRILSKAKIEPDGKKRALLDIENAIRNGADNKKPKLKCQKKGTTTELVEITLCSDKSGEHFIDCPHPFEPISPHYCPTNNIKY
What is the function of this protein?
Self-incompatibility (SI) is the inherited ability of a flowering plant to prevent self-fertilization by discriminating between self and non-self pollen during pollination.  In many species, self-incompatibility is controlled by the single, multiallelic locus S.
What are the official names of this protein?
Ribonuclease S-5, S5-RNase.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: BIOH_YERE8
Sequence: MKQLYWNICGEGDCDLVLLHGWGLNAGVWHCIIDRLTPHFRLHLVDLPGYGRSTEFGAMSLSEMAEIVLQQAPQQAIWLGWSMGGLVASQIALSHPERVRGLITVSSSPCFTAHDEWPGIRPEVLAGFQQQLSEDFQRTVERFLALQTLGTESARQDARLLKAVVLQHQMPEVAVLTGGLDILRTADLREELADCSLPFLRIYGYLDGLVPRKVAALLNSQWPHTQSVVMPGSAHAPFVSHPEAFSQLVVDFAQQSNT
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_INBSI
Sequence: MKAIIVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPNCLNCTDLDVALGRPKCMGTIPSAKASILHEVKPVTSGCFPIMHDRTKIRQLPNLLRGYENIRLSTRNVINAERAPGGPYIIGTSGSCPNVTNGNGFFATMAWAVPKDNKTATNPLTVEVPYICTKGEDQITVWGFHSDTETQMVKLYGDSKPQKFTSSANGVTTHYVSQIGGFPNQTEDGGLPQSGRIVVDYMVQKPGKTGTIVYQRGVLLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKERGFFGAIAGFLEGGWEGMIAGWHGYTSHGAHGVAVAADLKSTQEAINKITKNLNSLSELEVKNLQRLSGAMDELHNEILELDEKVDDLRADTISSQIELAVLLSNEGIINSEDEHLLALERKLKKMLGPSAVDIGNGCFETKHKCNQTCLDRIAAGTFNAGEFSLPTFDSLNITAASLNDDGLDNHTILLYYSTAASSLAVTLMIAIFIVYMVSRDNVSCSICL
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: NUBP2_DROPS
Sequence: MLDKVKNVIIVLSGKGGVGKSTVSTQLALALRHSGHKVGLLDIDLCGPSVPFLLGLEGSNIYQCDEGWVPIYTDASKTLAVMSIGFLLKNRTDPVIWRGPKKTMMIRQFLTDVKWEELDYLIIDTPPGTSDEHITVMECMREVPCNGAIIVTTPQSVALDDVRKEITFCKKTGIKLLGIVENMSGFVCPNCTNCTNIFSSNGGVELAHLVQIPHLGTLPIDPRVGVLAGSTASVLDELPDSPTAQVLRGIVQHLVALT
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP2K2_CANLF
Sequence: MLARRKPVLPALTINPAIAEGPSPTSEGASEANLVDLQKKLAELELDEQQKKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELSIGRYPIPPPDAKELEAIFGRPMVDGIEGEPHSISPRPRPPGRPISGHGTDSRPAMAIFELLDYIVNEPPPKLPNGVFTQDFQEFVNKCLIKNPAERADLKMLMSHTFIKRSEVEEVDFAGWLCKTLRLNQPSTPTRTAV
What is the function of this protein?
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases.  Activates the ERK1 and ERK2 MAP kinases (By similarity).  Activates BRAF in a KSR1 or KSR2-dependent manner; by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-BRAF dimerization and BRAF activation (By similarity).
What are the official names of this protein?
Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane localization is probably regulated by its interaction with KSR1.
Protein: EMAL1_MOUSE
Sequence: MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVSDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPTKARPLGQTLPLRTTVNNGTVLPKKPSASLPAPSGARKEVVVPVTKSINRTSSSERVSPGGRRESSGDSKGSRNRTGSTSSSSSGKKNSESKPKEPAFSPEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKAELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGGHLCAVDDSNDHVLSVWDWQKEERLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGNSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRRLISWNGNYQKLHKAEIPEQFGPIRTVAEGKGNVILIGTTRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVTDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHERKLLCTGDDFGKVHLFSYPCSQFRAPSHIYSGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI
What is the function of this protein?
Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division.  Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development.  Does not affect neuron migration per se.
What are the official names of this protein?
Echinoderm microtubule-associated protein-like 1, EMAP-1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EMAP family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Note=Detected in cytoplasmic punctae. Co-localizes with microtubules. Enriched in perinuclear regions during interphase and in the region of spindle microtubules during metaphase. Enriched at the midzone during telophase and cytokinesis. Detected at growth cones in neurons.
Protein: NUCA_NOSS1
Sequence: MGICGKLGVAALVALIVGCSPVQSQVPPLTELSPSISVHLLLGNPSGATPTKLTPDNYLMVKNQYALSYNNSKGTANWVAWQLNSSWLGNAERQDNFRPDKTLPAGWVRVTPSMYSGSGYDRGHIAPSADRTKTTEDNAATFLMTNMMPQTPDNNRNTWGNLEDYCRELVSQGKELYIVAGPNGSLGKPLKGKVTVPKSTWKIVVVLDSPGSGLEGITANTRVIAVNIPNDPELNNDWRAYKVSVDELESLTGYDFLSNVSPNIQTSIESKVDN
What is the function of this protein?
Catalyzes the degradation of both RNA and DNA; has the potential to act as an endonuclease.
What are the official names of this protein?
Nuclease, Endonuclease.
What is the protein family that this protein belongs to?
Belongs to the DNA/RNA non-specific endonuclease family.
What are the subcellular locations of this protein?
Periplasm. Note=Periplasmic or loosely attached to the cytoplasmic or the outer membrane.
Protein: IDI2_STAES
Sequence: MSDSQREQRKNEHVEIAMSQKDALVSDFDKVRFVHHSIPSIDVSQVDMTSHTTKFDLAYPIYINAMTGGSDWTKQINEKLAIVARETGIAMAVGSTHAALRNPNMIETFSIVRKTNPKGTIFSNVGADVPVDKALQAVELLDAQALQIHVNSPQELVMPEGNREFASWMSNIESIVKRVDVPVIIKEVGFGMSKETLQALYDIGVNYVDVSGRGGTNFVDIENERRSNKDMNYLSQWGQSTVESLLESTEFQDRLNIFASGGLRTPLDAVKCLALGAKAIGMSRPFLNQVEQSGITNTVDYVESFIQHMKKIMTMLDAPNIERLRQADIVMSPELISWINQRGLHLNRK
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_PSE14
Sequence: MRVADFTFELPDSLIARHPLAERRSSRLLTLDGPTGALAHRQFTDLLEHLRPGDLMVFNNTRVIPARLFGQKASGGKLEILVERVLDSHRVLAHVRSSKSPKPGSSILIDGGGEAEMVARHHALFELRFAEEVLPLLERVGHMPLPPYIDRPDEGADRERYQTVYAQRAGAVAAPTAGLHFDQPLLEAIAAKGVETAFVTLHVGAGTFQPVRVEQIEDHHMHSEWLEVGQDVVDAVAACRARGGRVIAVGTTSVRSLESAARDGELKSFSGDTDIFIYPGRPFHVVDALVTNFHLPESTLLMLVSAFAGYPETMAAYAGAIEHGYRFFSYGDAMFITRNPAPTAPQESAPEDHA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YG041_HUMAN
Sequence: MPYDQDSFSTLLGFLQASRKYSEFTLKCPICIYVPCQCFAVGFLKQSDQ
What are the official names of this protein?
Putative uncharacterized protein PNAS-138.
Protein: HS21C_WHEAT
Sequence: MAAANAPFALVSRLSPAARLPIRAWRAARPAPLSTGGRTRPLSVASAAQENRDNSVDVQVSQAQNAGNQQGNAVQRRPRRAGFDISPFGLVDPMSPMRTMRQMLDTMDRLFDDAVGFPTRRSPAARARRRMPWDIMEDEKEVKMRFDMPGLSREEVRVMVEDDALVIRGEHKKEAGEGQGEGGDGWWKERSVSSYDMRLALPDECDKSQVRAELKNGVLLVSVPKRETERKVIDVQVQ
What are the official names of this protein?
Small heat shock protein, chloroplastic, Heat shock protein 26.6.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TBA1_SCHPO
Sequence: MREVISVHVGQAGVQIGNACWELYCLEHGIGPDGFPTENSEVHKNNSYLNDGFGTFFSETGQGKFVPRSIYVDLEPNVIDQVRTGPYKDLFHPEQMVTGKEDASNNYARGHYTVGKEMIDSVLERIRRMADNCSGLQGFLVFHSFGGGTGSGLGALLLERLNMEYGKKSNLQFSVYPAPQVSTSVVEPYNSVLTTHATLDNSDCTFMVDNEACYDICRRNLDIERPTYENLNRLIAQVVSSITASLRFAGSLNVDLNEFQTNLVPYPRIHFPLVTYSPIVSAAKAFHESNSVQEITNQCFEPYNQMVKCDPRTGRYMATCLLYRGDVIPRDVQAAVTSIKSRRTIQFVDWCPTGFKIGICYEPPQHVPGSGIAKVNRAVCMLSNTTSIAEAWSRLDHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALERDYEEVGQDSMDNEMYEADEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AZOR_FRASN
Sequence: MPHLLHIDSSLAPEGSVSRGVAEAYAESWRKHHPDGTLTHRDLATSPPPHLNWALVSGGQTPPEQRTPEQAEAVKIREEYLEEVESADEYVISVPMYNYAYPSTIKAWLDQVIVMGRTAGGTAGDGVLAGRKVTVITAQGGSYAPGAPKEGWDHQVPYLRHAFEALGADNIEFITVVMTLSKVNPALAAFTDVFEASRTAAEQTARDRAAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: MRF2_ARATH
Sequence: MEHQDLTDSRKDPLCISQLKISSSSLDPLPQANMAEDLTKSRRHSPIKVEGSEETWGVEDDDDLTDPIFDTIEGNGHSDPTSCFDADLSEYKKKATVIVEEYFGTNDVVSVVNELKELGMAEYRYYFVKKLVSMAMDRHDKEKEMAAFLLSTLYADVIDPPEVYRGFNKLVASADDLSVDIPDAVDVLAVFVARAIVDDILPPAFLKKQMKLLPDNSKGVEVLRKAEKSYLATPLHAEVVEKRWGGTDNWTAEDVKARINDLLKEYVMSGDKKEAFRCIKGLKVPFFHHEIVKRALIMAMERRKAQVRLLDLLKETIEVGLINSTQVTKGFSRIIDSIEDLSLDIPDARRILQSFISKAASEGWLCASSLKSLSADAGEKLLENSSANVFKDKAKSIIREYFLSGDTSEVVHCLDTELNASSSQLRAIFVKYLITLAMDRKKREKEMACVLVSTLGFPPKDVRSAFSMLIESADDTALDNPVVVEDLAMFLARAVVDEVLAPRDLEEVLNQTPEAGSSVGEKVIQMAKTLLKARLSGERILRCWGGGGIETNSPGSTVKEVKEKIQILLEEYVSGGDLREASRCVKELGMPFFHHEVVKKSVVRIIEEKENEERLWKLLKVCFDSGLVTIYQMTKGFKRVDESLEDLSLDVPDAAKKFSSCVERGKLEGFLDESFASEDSQSKKQNGSSSSSG
What is the function of this protein?
Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions.
What are the official names of this protein?
MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 2, MA3 domain-containing protein 8.
What is the protein family that this protein belongs to?
Belongs to the PDCD4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: PCDB5_HUMAN
Sequence: METALAKTPQKRQVMFLAILLLLWEAGSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLLYEKLDREVMCGATEPCILHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPESTQPGTVFPLKIAQDFDIGSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDREERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVVVSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIVATDGGGLSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPETVVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAAPVGRCSVPEGPFPGHLVDVSGTGTLSQSYHYEVCLTGDSGAGEFKFLKPIIPNLLPQGAGEEIGKTAAFRNSFGLN
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-5, PCDH-beta-5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.