PharMolix/UniProtQA huggingface dataset:
Protein: AMYR_DROBP
Sequence: MFKFATAVILCLVAASSTLAQHNPHWWGNRNTIVHLFEWKWSDIAAECENFLGPRGFAGVQVSPVNENIVSAGRPWWERYQPISYKLTTRSGNEKEFADMVRRCNEVGVRIYVDVLLNHMSGDFDGIAVGTAGSEAEPSKKSYPGVPYSALDFHPSCEITDWNDRFQVQQCELVGLKDLDQSSEWVRSKLIEFLDHLIELGVAGFRVDAAKHMAADDLSFIYSSLSDLNIEHGFPHNARPFIFQEVIDHGHETVSREEYNQLGAVTEFRFSEGIGNAFRGNNALKWLQSWGTGWGFLPSGQALTFVDNHDNQRDMGAVLNYKSPKQYKMATAFHLAYPYGISRVMSSFAFDDHDTAPPQDEQEKIISPEFDEEGACVNGWICEHRWRQIYAMVGFKNAVRDTELSNWWDNGDSQISFCRGNKGFLAVNNNLYDLSQELQTCLPAGVYCDVISGSLVDGSCTGKSVTVDDNGYGYAHIGSDDFDGVLALHVDAKV
What are the official names of this protein?
Alpha-amylase-related protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLME_RHIEC
Sequence: MTKAPIAGNRTGRKLGQRVKNKKMKASSRQWLQRHINDPYVQRAQLEGYRARAAFKLLEIDEKYHILRGAKRIIDLGAAPGSWSQIAAKVTGSTDEDIRVAAIDFLEMAQLPGVWILQLDFLDPSAPGKLMEAVGGTPDLVISDMAAPTTGHHRTDHLRTMHLCEVAAHFAIEVLGEGGHFLTKTFQGGTERDLLAMLKQNFRQVVHVKPNSSRAESVEMFLLAKGFKGRKAEGDAEEA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCPC_VIBCH
Sequence: MKKTIISTLVIGLVSGCSNTNLLKDNLASEQSVINLSKSSNEAKSRNIEFLSGAYLSERKVPKHDIKFSGKYVEFESKSPIELIDVLDGLSKQYNIQYVFSDELEDENSEENKKSSGSSSAKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKNQVFNLQQYFDDNKFSSSMQIGGTSGTSSGLKGTADTAIESNSWEKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLLLHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQVGGGLGASYRSASARLDAVVNELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDTNTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSRKQLVSIGTAQGITLPTVDENESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDLASNRVNIYD
What is the function of this protein?
Involved in TCP pilus biogenesis.
What are the official names of this protein?
Toxin coregulated pilus biosynthesis outer membrane protein C, TCP pilus biosynthesis protein TcpC.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: IQCF3_RAT
Sequence: MELDQDQKVETPEAAENGKDEMQLEEQTQDEDTTETETETETETEAEAEGADGTILERTESVKAKLVPQAEKQIQDEKTGIKEADRAIQEQTQDDETEAEGADGAILKRSESVKVKLIPQAEKQIQDEKTGIKEADRAIQELPANAELAGVKIQAWWRGTLVRRTLLLAILSAWTIQSWWKETKSRLQGRKLHDVMRCRLRNLNLKSISRRKRPNQSSFL
What are the official names of this protein?
IQ domain-containing protein F3.
Protein: LOLD_VIBPA
Sequence: MNKLLECRDIRKVYREGSLDTEVLKGVSFDIDKGELVSIVGSSGSGKSTLLHILGALDDATQGEVDFLGQNLSALSSNKQAALRNKHLGFVYQFHHLLADFTALENVAMPLLIGGIKVTEAKQAAKALLEKVGLSHRMDHRPSELSGGERQRVAIARALVNKPDLVLADEPTGNLDHNTALAIYDLMRELNKESNIAFLVVTHDNELAAKMDRQMHMQDGLLVDRLMTESASVEG
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CAPSD_DHBVQ
Sequence: MDINASRALANVYDLPDDFFPKIDDLVRDAKDALEPYWKSDSIKKHVLIATHFVDLIEDFWQTTQGMHEIAESLRAVIPPTTAPVPTGYLIQHEEAEEIPLGDLFKHQEERIVSFQPDYPITARIHAHLKAYAKINEESLDRARRLLWWHYNCLLWGEANVTNYISRLRTWLSTPEKYRGRDAPTIEAITRPIQAAQGGRKTSSGTRKPRGLEPRRRKVKTTVVYGRRRSKSRERRAPSPQRAGSPLPRSSSSHHRSPSPRK
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsid appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsid are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stucked in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genome for transcription, or bud through the endoplasmic reticulum to provide new virions (By similarity).
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus core antigen family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm.
Protein: KBAZ_ECOLC
Sequence: MKHLTEMVRQHKAGKTNAIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCLEHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKVCSGLRQVLEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYHTACEGQ
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of KbaY.  When expressed alone, KbaZ does not show any aldolase activity.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. KbaZ subfamily.
Protein: RM16_DICDI
Sequence: MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI
What are the official names of this protein?
60S ribosomal protein L16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARFJ_ARATH
Sequence: MEQEKSLDPQLWHACAGSMVQIPSLNSTVFYFAQGHTEHAHAPPDFHAPRVPPLILCRVVSVKFLADAETDEVFAKITLLPLPGNDLDLENDAVLGLTPPSSDGNGNGKEKPASFAKTLTQSDANNGGGFSVPRYCAETIFPRLDYSAEPPVQTVIAKDIHGETWKFRHIYRGTPRRHLLTTGWSTFVNQKKLIAGDSIVFLRSESGDLCVGIRRAKRGGLGSNAGSDNPYPGFSGFLRDDESTTTTSKLMMMKRNGNNDGNAAATGRVRVEAVAEAVARAACGQAFEVVYYPRASTPEFCVKAADVRSAMRIRWCSGMRFKMAFETEDSSRISWFMGTVSAVQVADPIRWPNSPWRLLQVAWDEPDLLQNVKRVSPWLVELVSNMPTIHLSPFSPRKKIRIPQPFEFPFHGTKFPIFSPGFANNGGGESMCYLSNDNNNAPAGIQGARQAQQLFGSPSPSLLSDLNLSSYTGNNKLHSPAMFLSSFNPRHHHYQARDSENSNNISCSLTMGNPAMVQDKKKSVGSVKTHQFVLFGQPILTEQQVMNRKRFLEEEAEAEEEKGLVARGLTWNYSLQGLETGHCKVFMESEDVGRTLDLSVIGSYQELYRKLAEMFHIEERSDLLTHVVYRDANGVIKRIGDEPFSDFMKATKRLTIKMDIGGDNVRKTWITGIRTGENGIDASTKTGPLSIFA
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).  Could act as transcriptional activator or repressor.  Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Auxin response factor 10.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ELOB_MOUSE
Sequence: MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPEEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADDTFEALRIEPFSSPPELPDVMKPQDSGGSANEQAVQ
What is the function of this protein?
Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins.  This includes the von Hippel-Lindau ubiquitination complex CBC(VHL).  By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.  As part of a multisubunit ubiquitin ligase complex composed of elongin BC complex (ELOB and ELOC), elongin A/ELOA, RBX1 and CUL5; polyubiquitinates monoubiquitinated POLR2A (By similarity).  A number of ECS complexes (containing either KLHDC2, KLHDC3, KLHDC10, APPBP2, FEM1A, FEM1B or FEM1C as substrate-recognition component) are part of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  ECS(LRR1) ubiquitinates MCM7 and promotes CMG replisome disassembly by VCP and chromatin extraction during S-phase (PubMed:33590678).
What are the official names of this protein?
Elongin-B, EloB, Elongin 18 kDa subunit, RNA polymerase II transcription factor SIII subunit B, SIII p18, Transcription elongation factor B polypeptide 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRIO_SAPAP
Sequence: MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNLYPPQGGGWGQPHGGGWGQPHGGGWGQPHGGSWGQPHGGGWGQGGGTHNQWNKPSKPKTSMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: DNAG_METLZ
Sequence: MYSIDSIKYLIHIHIEAEGVVEKTDVVGAIFGQTEGLLGEELDLRDLQRSGRIGRIDVQIVSKHGKTAGECYIASSLDRAETAILAAALETIDRIGPCMAAIRIQNIEDLRAIKRRQIVERAKELLLESFDEVGISTYDILTEVREASRVEKITTIGPERLPAGPAVLESDAIIIVEGRADVLNLLKCGINNTVAVEGTKVPETVIDLSAKKNTTVFVDGDRGGDLILRELLQVADIDFVAFSPRRRSVEDMSRKEIVKSLRNKVPASVLKSHIEKDEPISDLVFEIEAGEEEHSSVSQKEEGNNTTPDVPADLPEEPPKSNIDEAIIPPITTSEQNLVKPENPHTIQEHTQYMKNTGRSRVLAEDAGVIGDYSLQELKAILPKLNDDVAGVIVDAAVDQKFIDQAFAKGLTYVAANAFEGIVRRPAGLRLIPF
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: NPM2_HUMAN
Sequence: MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
What is the function of this protein?
Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development.  Probably involved in sperm DNA decondensation during fertilization.
What are the official names of this protein?
Nucleoplasmin-2.
What is the protein family that this protein belongs to?
Belongs to the nucleoplasmin family.
What are the subcellular locations of this protein?
Nucleus. Note=Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm.
Protein: CLE27_ARATH
Sequence: MTHAREWRSSLTTTLLMVILLSYMLHLFCVYSRVGAIRIFPETPASGKRQEEDLMKKYFGAGKFPPVDSFVGKGISESKRIVPSCPDPLHN
What is the function of this protein?
Extracellular signal peptide that regulates cell fate.  Represses root apical meristem maintenance.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 27.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[CLE27p]: Secreted, extracellular space.
Protein: ILVC_CALS4
Sequence: MAKMYYDQDADAEVLKGKKIAVIGFGSQGHAHALNLRDSGFDVVVGLYEGSKSKERAEKEGLTVLTVEEAAKVADVIMMLIPDEKQAKVYKESIEKNLTEGKALAFAHGFNIHFKQIVPPENVDVFMVAPKGPGHLVRRMYQEGKGVPCLVAVHQNYTGKALDIALAYAKGIGGTKAGAIETTFKEETETDLFGEQAVLCGGLTELMKAGFETLVEAGYQPEIAYFECVNEMKLIVDLIYEGGFSYMRYSISDTAEFGDYMTGKRIITEETRKEMKKILEEIQTGKFAKEWLLENQVGRPQYNAIKEREANHPIEKVGKSLREMMPWLSKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: TET5_ENTFL
Sequence: MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTDNTLLERQRGITIQTAITSFQWKNTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELHPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDPVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVAPLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT
What is the function of this protein?
Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
What are the official names of this protein?
Tetracycline resistance protein TetM from transposon Tn1545, TetM(1545).
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TetM/TetO subfamily.
Protein: RRF_FLAJ1
Sequence: MTEEIDFILESTEESMNGSIAHLEKEFLNIRAGKASPAMLGGVFVDYYGSATPLSQVSKISVPDARTITLQPFEKNMLQAIEKAILIANIGFNPMNNGDVIIISVPPLTEERRRDLAKQAKSEAEDAKIGIRNVRKDANTDIKKLEKEGTSEDICKSAEEEVQNLTNTYIKKIDELLAAKEAEIMKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIX2_SOLLC
Sequence: MGKRTNPRHFLVTWSLLLLETAFGLTSREVNKTLCIEKERDALLEFKRGLNDDFGRLSTWGDEEECCNWKGIECDKRTGHVIVLDLHSEVTCPGHACFAPILTGKVSPSLLELEYLNFLDLSVNGFENSEIPRFIGSLKRLEYLNLSSSDFSGEIPAQFQNLTSLRILDLGNNNLIVKDLVWLSHLSSLEFLRLGGNDFQARNWFREITKVPSLKELDLSVCGLSKFVPSPADVANSSLISLSVLHLCCNEFSTSSEYSWLFNFSTSLTSIDLSHNQLSRQIDDRFGSLMYLEHLNLANNFGAEGGVPSSFGNLTRLHYLDMSNTQTYQWLPELFLRLSGSRKSLEVLGLNDNSLFGSIVNVTRFSSLKKLYLQKNMLNGFFMERVGQVSSLEYLDLSDNQMRGPLPDLALFPSLRELHLGSNQFQGRIPQGIGKLSQLRIFDVSSNRLEGLPESMGQLSNLERFDASYNVLKGTITESHFSNLSSLVDLDLSFNLLSLNTRFDWVPPFQLQFIRLPSCNMGPSFPKWLQTQNNYTLLDISLANISDMLPSWFSNLPPELKILNLSNNHISGRVSEFIVSKQDYMIIDLSSNNFSGHLPLVPANIQIFYLHKNHFSGSISSICRNTIGAATSIDLSRNQFSGEVPDCWMNMSNLAVLNLAYNNFSGKVPQSLGSLTNLEALYIRQNSFRGMLPSFSQCQLLQILDIGGNKLTGRIPAWIGTDLLQLRILSLRSNKFDGSIPSLICQLQFLQILDLSENGLSGKIPQCLNNFTILRQENGSGESMDFKVRYDYIPGSYLYIGDLLIQWKNQESEYKNALLYLKIIDLSSNKLVGGIPKEIAEMRGLRSLNLSRNDLNGTVVEGIGQMKLLESLDLSRNQLSGMIPQGLSNLTFLSVLDLSNNHLSGRIPSSTQLQSFDRSSYSGNAQLCGPPLEECPGYAPPIDRGSNTNPQEHDDDDEFSSLEFYVSMVLGFFVTFWGILGCLIVNRSWRNAYFTFLTDMKSWLHMTSRVCFARLKGKLRN
What is the function of this protein?
Involved in plant defense.  Confers resistance to the fungal pathogen T. viride through recognition of the EIX elicitor protein.
What are the official names of this protein?
Receptor-like protein EIX2, EIX receptor 2.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RMD9_PICST
Sequence: MFRLVSSNAQGSFRSSLLTKVRIPISVPASSPLNTSTSNNTTTNNNNFGVNNSTNNTQFTRHQSSAAVDLSARKVYQDEFLRSHSSFTAPDHETKVKLNHFKELLVTGNQKLRALNRQEARAFYSVLQSLSHMLEDAKLRRSLNVDLLHQYSLLLHSAIFSSRTNRLAEKRNRDKDEYNATSYTDEVVLRGSVLNFAQLVEAGEFKYCFTDKVLQYLLYSMFQFKFNTEALNLWENGVNDAETGSVYLRPLVLATVLPRAFELKRFTYEEILHIYELNTKKEQFPHHTLVTAMGKIAIHAGDYSRALDFLERLLEKYDQKPTGLKLASLSDLHLSFIGDCKEIAIAKHFFDKVIEDELPYKVLLKVPYVTSLLDNAYQAGDSLEEAIYFWKNSVAYYMKTRQQLNSRYSLLNNKFFELFFQAYPELNEESFAMLRDLITFYAQTKPLDETFLNTIITHYSWKSKEVLDQLMQNYEIYEVERTPVSHRICLKKTGQYADYTNEEILARWNENLKCLDNSKYFYIPNADWSALRDATIYSIVPDKRTDLYYSVLNTYKNYMQDARACIKFVGNWTKRPAYLESIARITLEKNFEPAVKVDVPLFRNLKENVNYADATRDLIITARNSKPRV
What is the function of this protein?
Binds the 3'-UTR of mitochondrial mRNAs.  Involved in the processing or stability of mitochondrial mRNAs.
What are the official names of this protein?
RNA-binding protein RMD9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RMD9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ZN491_HUMAN
Sequence: MGERLFESAEGSQCGETFTQVPEDMLNKKTLPGVKSCESGTCGEIFMGYSSFNRNIRTDTGHQPHKCQKFLEKPYKHKQRRKALSHSHCFRTHERPHTREKPFDCKECEKSFISPASIRRYMVTHSGDGPYKCKFCGKALDCLSLYLTHERTHTGEKRYECKQCGKAFSWHSSVRIHERTHTGEKPYECKECGKSFNFSSSFRRHERTHTGEKPYKCKECGKAFNCPSSFHRHERTHTGEKPYECKLYGKALSRLISFRRHMRMHTGERPHKCKICGKAFYSPSSFQRHERSHTGEKPYKCKQCGKAFTCSTSFQYHERTHTGEKPDGCKQCGKAFRSAKYIRIHGRTHTGEKPYECKQCGKAFHCVSSFHRHERTHAGEKPYECKHCGKAFTCSIYIRIHERIHTGEKPYQCKECGKAFIRSSYCRKHERTHTINI
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 491.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTL_THEM4
Sequence: MGKIKKLDKNVVSRIAAGEAVAGPFSVVKELVENALDASATKIEIEILNGGKSYIKVKDNGEGMSRDDLLLSIEEHTTSKIEDFEDIYNLYSFGFRGEALSSISKVSKLVITSNDGKESNRLEVIGGKIKDIKEYPTSEKGTIVEVYDLFFNVPARRKFLKSDNVEKRYVVEYVEKFLLGNPDVEIVLKSDGEVVYNAVKGNLEDRFRLIFPEVREFTEVSGKYVKGIISSPSYYRNNRTGQIFFVQKRFVIDKMLYYIFETGYGEALLKHPYGVLFIEVPPRFVDVNVHPQKLEVKFSNPNVIYSDITRTVREGIKKFVSKKIFVKKEQNTVNENKLNYAYGPKSKPFQTNIEKNMLFNVEKKQLEVKRDIVVLKKRYVLFESNDGIYIMDFHAAHERILYDNIIKQLDEKVERLDLMIPIEIKIGKSFLQIAEGRKEDFKRFGFNIKIDKEKIIVLSIPSFIKPSDVVEVLMEILDEYRILGENPKSMKHIIADKACKKAVKTGYDILESEAKQLVEEVLKRGLTTCPHGRPLFLKITYKELDSFFERT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: KR103_HUMAN
Sequence: MATSTMSVCSSAYSDSWQVDACPESCCEPPCCATSCCAPAPCLTLVCTPVSCVSSPCCQAACEPSPCQSGCTSSCTPSCCQQSSCQPACCTSSPCQQACCVPVCCKPVCCVPVCCKPVCCKPICCVPVCSGASSSCCQQSSRQPACCTTSCCRPSSSVSLLCRPVCRSTCCVPIPSCCAPASTCQPSCCRPASCVSLLCRPTCSRLSSACCGLSSGQKSSC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 10-3, High sulfur keratin-associated protein 10.3, Keratin-associated protein 10.3, Keratin-associated protein 18-3, Keratin-associated protein 18.3.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 10 family.
Protein: GLND_CERS4
Sequence: MAPASEAGPAQDPLFSGLILPRSRILDAEALTRSILAEIDAAGPLDPKSARAIAVRQMTEAKAAGNRALSETFEARPREARGLIRAQAALTDGLVTAALRVACERLHPLANPTEAERIAVLAVGGYGRAEMAPHSDVDLLFLTPWKITPWAEMVIESMLYMLWDLRLKVGHSSRTVKDCLRLGREDITIRTALLEHRFLAGHAPLAAELDETLWNDLFRGTGAEFIDAKLEERGQRHKRQGGQRYVLEPNVKEGKGGLRDLQTLYWIGKYLNRVPSPSGLVAAGLLTRDEFETFERAESFLWAVRCHLHYATGRATDQLTFDLQVEVAARMGYADTRGRRGVEVFMQDYFRHATRVGELTRVFLAQLEARHEKREPKIMGLFRRKKRLKPEYSLVNGRIDVLDPKAFLADKLNLLRIFEEALRTGFLIHPGAMRLIAANLHLIDEEMQHDREANRIFLDMLLRHGNPERALRRMNELGVLGAFIPEFERIVAMMQFNVYHHYTVDEHTIQCISTLAQIERHELDEELPIANRILTDGISRRVIYVALLLHDIGKGRPEDHSILGAQIARRVAPRFGLTAEECETVEWLVRYHLLMSDMAQKRDIGDPRTVRDFAKAVRSKKRLDLLTVLTVCDIRGVGPGTWNNWKAQLLRKLYRDTVTALDAGLESLNRENRADEAKRALRELLEEWDPKDLRAELARHYPPYWQALSNATHAVFARMLRGLGETEIRIDLDPDPDRDATRACFALADHPGIFSRLAGALALVGANVVDARTYTTKDGYATAVFWIQDSEGSPYEISRLPRLTSMIDKTLKGEVVAREALKDRDKLKKREAQFRFPTHIAFDNEGSDIYTIIEVDTRDRPGLLYDLTRTLAANNIYIASAVIATYGAQVVDSFYVKDMFGLKLHQKNRQETLEKKLRQAIVEGAERAKQ
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.