PharMolix/UniProtQA huggingface dataset:
Protein: RS5_ROSS1
Sequence: MIKRRINADELELEERVVQINRVSKVVKGGRRFSFSTVVVVGDGKGHVGIGMGKAAEVPEAIRKGVEAAKKNLIRVPLSGTTIPHEVQMEFAASKVRLLPAAPGTGVIAGRGVRPVLEMAGIKDVLSKRYGSNNPINVVKATFKALSALTSLEEQARMRGMTPRELNLRRMRREPAPQEA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HPRT_METHJ
Sequence: MYPILVNSLLTCPIVKKGEYNYFVHPITDGIPDIDPGLLREIAVGMIRLLDLTDVKYIVTAEAMGIPIATAISLMTDIPVNIIRKRKYGLPGECDVCQVTGYSKGEMYINGICTGDRIVIVDDVISTGGTMNGIIKSLQSIGAEIADIGFVIKKGNPSLKLPYSYLVSIEVTDRVRIIDQSF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
What are the official names of this protein?
Hypoxanthine/guanine phosphoribosyltransferase, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAMA_YERPG
Sequence: MAMKKLLIASLLFGSATVYGADGFVVNDIHFEGLQRVAVGAALLNMPVRVGDTVSDDDIGKTIRALFATGNFEDVRVLRDGNTLIVQVKERPTIASITFSGNKAVKEDMLKQNLEASGVRVGEALDRTTISNIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFTEGVSAKIQQINIVGNHSFTTDELISRFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSFYLDRGYARFNIDSTQVSLTPDKKGIYVTINITEGPQFKLNSVIVSGNLAGHQSEAEKLTKIEPGELFNGSKVTRMEDDIKKMLGRYGYAYPRVVTQPEINDDDKTVKLHINVDAGNRFYVRHIRFEGNDTSKDSVLRREMRQMEGAWLGNDQVEAGKERLNRLGYFETVDVETQRVPGAADLVDVTYKVKERNTGSLNFGIGYGTESGVSFQVGVQQDNWLGTGNTVGINGTKNDYQTYAEFTLMDPYFTVDGVSLGGRIFYNDFKADNADLSGYTNSSYGADGTLGFPINENNSLRVGVGYVHNDLSDMLPQVAMWRYLESVGERPGYDGREGFTTDDFTLNLGWTYNNLDRGFFPTSGVKSSVNTKITVPGSDNEFYKVTFDTSAYQPLNEDRSWVLLGRGRLGYGDGIGSKEMPFYENFYAGGSSTVRGFRSNNIGPKAAYYANGGATVTNSTDAVGGNAMAVASIELITPTPFISEKYSNSVRTSIFIDSGTVWDTNWENTAKTRAAGIPDYGKASNIRVSAGVALQWMSPLGPLVFSYAKPVKDYEGDKSEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: GTHB1_MORSA
Sequence: MQLVVMVAVLALAGAGQGCSFGCHPTNISIQVESCGLTEVIYTTICEGQCYHEDLVYISHYERPEQRICNGDWSYEVKHIKGCPVGVTYPVARNCECTTCNTENTDCGRFPEDIPSCLSF
What is the function of this protein?
Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Gonadotropin subunit beta-1, GTH-I-beta, Gonadotropin beta-I chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLCN5_PIG
Sequence: MAMWQGAMDNRGFQQGSFNSFQSSSSDEDLMDIPGTAMDFSMRDDVPPLDGEIEEDKSYNGGGLGSSYRMMDFLEEPIPGVGTYDDFNTIDWVREKSRDRDRHREITNKSKESTWALIHSVSDAFSGWLLMLLIGLLSGSLAGLIDISAHWMTDLKEGICTEGLWFNHEHCCWNSKHVTFKDRDKCPEWNSWSQLIISADEGAFAYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLIIKTITLVLAVSSGLSLGKEGPLVHVACCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIRTNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENRFNTSKAAELPDRPAGAGVYSAMWQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHHDWAIFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLEAKEEFAHKTLAMDVMKPRRNDPSLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPMPPYTPPTLKLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMANQDPDSILFN
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges chloride ions against protons (PubMed:10978325).  Important for normal acidification of the endosome lumen.  May play an important role in renal tubular function (By similarity).  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons.  The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable).
What are the official names of this protein?
H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: SYW_SULTO
Sequence: MAQDFNVTPWEVKGKVDYDKLIVQFGTQKITSELKEKIKSIINDELHVMLRRDVFFSHRDLDLVLKDYQDGKGFFLYTGRAPSLGMHIGHLIPFIFTKWLQDKFNVNLYIEITDDEKFMRNPEYTLDQTRQWAYDNILDIIAVGFNPDKTFIFQDTEYIRNMYPIAIKIAKKLTFSEVRATFGLDTSSNIGIIWYPALQIAPTMFEKRRCLIPAGIDQDPYWRLQRDIAESLGYYKAAQIHSKFLPPLTGPEGKMSSSQPETAIYLTDDPKTVERKIMKYAFSGGQPTIELHRKYGGNPDIDVSFQWLYMFFEPDDNKIKKIEEDYRSGALLTGELKQILIEKLNDFLEEHRQKREEAKKLVNVFKYDGELAREMWRKIHE
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODA_SINTE
Sequence: MCSRVRWTLRWESELQLDDHVELASFFRKTYGPTGAFNAKPFEGSRSWAGARPELRAIAYDSNGVAAHMGLLRRFIKVGEVDLLVAELGLYGVRPDLEGLGISHSLRVMYPVLQQLRVPFGFGAVRHALQKHVERFGRHVPANVLSGIRVRSTLPDARLDLPPTRIEDVLVVVFPVELAMSDWPTATFIDRNGPEL
What is the function of this protein?
N-acyltransferase required for nodulation.  Acts in the production of a small, heat-stable compound (Nod) that stimulates mitosis in various plant protoplasts.
What are the official names of this protein?
Nodulation protein A.
What is the protein family that this protein belongs to?
Belongs to the NodA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIJ_METTH
Sequence: MQTPEIKEGTEQYLWRRKTMNPGDKGVKRKGSDRQREKMSVIVMAGTEDARRIISRLSGMPWVEVTATATTEHGSDLAEKSGASRTVTGALDSDGLRELMADLDACILIDATHPFAAQATENALRACRETGTIYVRFERPEVIPDGVIRVGSFREAGEVASSLIGDGEVVMHLAGVSTLGDVLRSLEPERVAVRVLPSTSSIEKCLQLGVPPSHIIAMQGRFSAEMNLALLREYRAGAVITKESGETGGLPEKVEAASELGIPVILVERPEVNLEGEAVFGNINDLMDHVLKILRDMGQPGD
What is the function of this protein?
Catalyzes the reduction of the macrocycle of cobalt-precorrin-6A to cobalt-precorrin-6B.
What are the official names of this protein?
Cobalt-precorrin-6A reductase.
What is the protein family that this protein belongs to?
Belongs to the precorrin-6x reductase family.
Protein: NRDR_RHOCS
Sequence: MRCPFCGNDDTQVKDSRPTEDNSAIRRRRFCPACGARFTTFERVQLRELTVVKSGGSREPFDREKLLRSMRIALRKRPVDADRIDRVVNSIVRQLESSGETEIPSSQIGEMVMVHLGTLDKVAYVRYASVYKDFREVTDFNQFVETLRTDAPAG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CMOB_ECOSM
Sequence: MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSNAVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVSVTTTEEQRRTEWMVTESLADFLDPHDPSKTVEGYPAPKRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: ATP6_STRLI
Sequence: MRHAEGAAVSADPTQVLAFETDCHIFDGCGFPSPGLHSFLFEPLWGDHDSNLYFNKPMLLALLGSIVIVGFFWAAFRKPKVVPGKLQMVAEAGYDFIRRGVVYETIGKKEGEKYVPLVVSLFFFVWMMNLWSIIPVAQFPVTSIIAYPAVLAAIVYVTWITLTFKRQGFVGFFKNVTGYDKSLGPVLPLAMLIEFFSNILIRPFTHAVRLFANMFAGHTLLLLFTIASWYLLNGVGIAYAGVSFIMTVVMTAFELFIQALQAYVFVLLTCTYIQGAMAEHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFP_BRUMB
Sequence: MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAESVERVRLEQKDFSFLYEQGEALIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEKPIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIRIPVPPFIASGERVIVDTNELTYISRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_PYRAE
Sequence: MLPREIEELLNIILQHNTWRRKETINLIASENVMSPLAELVYVNDFAGRYAEGTVGNRYYQGTKYVDILEDSLSKRFAKVLDAKFVDVRPISGTIANLATYHALVPEGGIVASLPVKYGGHISHNTVGGLKALRVKTVELPWDFENFNIDIDAARKIIEEKRPNLIILGASLYLFPHPVREIANAAKAVGAYVLHDSAHVFGLIIGGVFPNPLKEGAHVITSSTHKTFPGPQGGLIASVTDEELNNAIQRAVFPVFTSNYHLHRYAATYVTLIEMEHFGAEYGARIVENAKALAEALAEEGVTPVGERLGYTKTHQVAVDVSKFGGGDKVARLLEEANIIVNKNALPWDKSVLKPSGIRMGVQEMTRFGMGKGEMKEIAKFIARVLKGEDPTAVKREVVEFRKTFIEIKYGFKIDKEIIDKIFYSLNLYT
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_ECO5E
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_FUSNN
Sequence: MMQLMKITIKGNKLILDNDKIIYLTKEMFSKFDLKDKTSLDDETFYSLIYFRIKLSAYTMLAKRDYFKKELKNKLIEKIGFADIVKDVVEDFEEKGYLDDYEKAKSYAAQHSNYGTKKLSFILYQMGVDKEIVSEILEDEKDNQIEKIKQLWIKLGNKEYKKKIESILRKGFLYGDIKKAISSLEEEEE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_METMA
Sequence: MTEREQFFRDVNKIVIKIGTSSITRKGCDHTRENCNIDPAFMESIAFQVSELRKQGKEVIIVSSGAIGVGLNELGIAPKPREIPIRQAAAAVGQSMLMQDWSRAFSRYGMKVAQILLTYEFYSDRVTYLNLRNSISTLLEYGVVPIINENDCTCTNEIEAIFGDNDKLSAMVASKIDADLLIILSDIDGLFDRNPKTHIDAKLLTIVKKITPEIESYGGDPTSFKGVGGMRTKIKAAKICSMAGCYVVIANSDVEDVILKIASGEEIGTLFLAERHIQKNRARWIILARASGTVRVDAGAKAAVLGKNSLLPAGVVDVEGTFDRGDVVKLECDGKIFAKGITDYTSEELIKIKGVHTDQIENVLGYSNYNNVIKKENIGILEELN
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_NEIG2
Sequence: MITLTHYLVLGALLFGISAMGIFMNRKNVLVLLMSIELMLLAVNFNFIAFSQHLGDTAGQIFVFFVLTVAAAESAIGLAIMVLVYRNRQTINVADLDELKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FB97_ARATH
Sequence: METPNDLVKEEKRQGASENQDWSKLCPDLLRPILESLSSIDFHRAKTVCSDWYSVWKTCKGYDSKWNQNSGSIFDMAYKNSKLYLYTLDHHIKIYDFSGDSPKEEGLTNPYSNHPFRFDEKPQEYIWKRKIVIAESGEMMNEMLIFGHGVTMRAQVHDVGDGIKRDSICFVEDDLWPDFDRPSNCGIFNLATSRITWPKRYGVYIDQKQWFLPGFA
What are the official names of this protein?
Putative F-box protein At2g03610.
Protein: SYP_LACAC
Sequence: MRQSKFFMPTLKEAPSDAVAESHKLMIRGGYIRQVTAGVYAYLPLGYRVLRKAESIIEQEMDNINVPEMMMPHLLPATLWQESGRYQKYGAEMFKLKDRHGRESLLGPTHEETFTEIIAKNLKSYKQMPLALYQIQTKFRDENRPRFGLLRGREFVMLDGYSFAATREQLDQQFDDQKSAYKRIFKRAGVTVHPVIADSGTMGGKNSTEFQAPAAIGEDTIATNEKGTYAANLEMAKSIDTFKQEPEEAKELTKVATPACDTIKKLAEFLDVPATRIVKSILYIADDQKVLVLIRGDKQINEVKLGHVLDADDIHEANTEDLKEITGSEKGGVGPVNADWADKIIADETVKGLYNVVVGAGETDYQFKNANLDRDFKVDEFADIRTANEGEPDPVDHLPLKFTTSIEVGHIFKLGTYYTKTMGADFLDQNGKAQPVIMGSYGIGVTRMLSAVVEQHLTDRGVAWPKEIAPFEIHIVQMKMNKEDQTELAEKLEKKFSEKYDVLYDDRKERAGVKFADADLVGAPVRITIGKKAADGIVEVKRPTDEKAVEMSIDELDKFVNQELG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_HALH5
Sequence: MLGLLKKVVGDPSQRQLKKNQKIADQVEALSDEMKSLSDDGLRQKTEEFKKRYKNGESLDDLLPEAYAVVREAATRVLNMTPYPVQILGAIALHQGNIAEMKTGEGKTLVGTMPVYLNALAGKGVHVVTVNDYLARRDSEQMGAMFEFLGLTVGLNVPGLSKEEKKEAYQADITYGTNNEFGFDYLRDNMVLYKEQMVQRSLNFALVDEVDSILIDEARTPLIISGSVERSTKLYSQANSFVRVLKNEEDYTLDEKTKSVQLTEEGVNKAERAFNIDNLFDQRHVQLLHHINQAMKAHVVMHRDADYVVENGEIVIVDQFTGRLMKGRRYSDGLHQAIEAKEGLQIQRESMTLASITFQNYFRMYQKLAGMTGTAKTEEEEFRNIYGMDVMVIPTNKPVIRDDRPDLIFKTMDAKFKAVVNEIEELYKKGQPVLVGTVSVETSELVSTLLKKRRIPHHVLNAKNHEKEAEIIENAGHRGAVTIATNMAGRGTDIKLGEGVRELGGLHVLGTERHESRRIDNQLRGRSGRQGDPGSSQFYLSMEDELMRRFGSDNMRAMMDKLGMEEDQPIESKLVSRAVETAQKRVEGNNFDARKQILQYDDVMREQREIIYKQRMEVLESDNLREIVEKMILSVIERNVQLHTPESEVPEDWDYGAIVNFMKANLLNEDDLTEKDIWGKDPEEIVEIIYDKVIERYNKKEEEFTPEHMREFEKVIMLRTVDRKWMNHIDQMDQLRQGIHLRAYGQNDPLREYRFEGFEMFEAMVASIEEEVAMYVMKAQVQQNLQREKVAEGQAVQPKPTDGDSKAKRQPVRKKETVGRNEPCPCGSGKKYKNCCGQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
Protein: SDHB_RICFE
Sequence: MAELRLPPNSVVKKGKEHKEQEEMLKPRKVKIYRYDPDLDENPTIDSFEIDLSKTGPMVLDALIKIKNEIDSTLTFRRSCREGICGSCSMNIDGTNTLACIKPIEEISGDIKIYPLPHMKVVKDLVPDMSHFYAQYESIEPWLKTDSPTPSNSERLQSIKGREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAILLQAYRWIADSRDDHTGERLEDLEDPSKLYRCHTIMNCTKTCPKGLNPAKAIGKIKSLIAERHGV
What are the official names of this protein?
Succinate dehydrogenase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
Protein: HISX_PROMT
Sequence: MTQIINKDEVQETSSKKLTIKTANSIDQAQFELRKITERTSGTVQDEAIKVVDDILKNVRERGDEALTEYTSRFDGFLTEKFQVSSDLILKAWEETPRELQDSLLLAKKRIEKFHSLQVPKNITYTGPNGETLGRRWSPVEKAGIYVPGGRAAYPSTVLMNAIPAYVAGVNQIIMVSPANSQGEINQTVLAAAHITGINKIFRLGGAQAICALASGTESIPKVDVITGPGNIYVTLAKKKVYGKVGIDSLAGPSEILIIADQSAKLEHVASDMLAQSEHDPLASAILITTNTKLAEKLPAEINRQLINHPRLKICQESISNWGLIVLCDDLETCAQLSDTFAPEHLELLVEDPKKLSESINNAGAIFMGPWSPEAIGDYLGGPNHTLPTSGTARFAGALGVETFMKNTSLIDFSKEAFNENKNAVVQLANSEGLHSHAESIRIRDSKSF
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: BZP44_ARATH
Sequence: MNNKTEMGSSTSGNCSSVSTTGLANSGSESDLRQRDLIDERKRKRKQSNRESARRSRMRKQKHLDDLTAQVTHLRKENAQIVAGIAVTTQHYVTIEAENDILRAQVLELNHRLQSLNEIVDFVESSSSGFGMETGQGLFDGGLFDGVMNPMNLGFYNQPIMASASTAGDVFNC
What is the function of this protein?
Transcription factor that binds to the DNA G-box motif 5'-CACGTG-3' of MAN7 promoter.  Involved in the positive regulation of seed germination through MAN7 gene activation.  MAN7 is required for both, loosening of the micropylar endosperm, and rupture of the seed coat in germinating seeds.
What are the official names of this protein?
bZIP transcription factor 44, AtbZIP44.
What are the subcellular locations of this protein?
Nucleus.
Protein: CUTC_ENTFA
Sequence: MIKEFCAENFTKIPQAIQKGANRIELCDNLAVGGTTPSTGVIEEVLAYAGEHSVPVMTIIRPRGGNFVYNDIELKIMHTDLIEAKKLGTDGIVIGCLTEDGWLDEEALDLFIETAEGLQITFHMAFDALSKENQFKAIDWLAERGVTRILTHGGPAGTPIEDNFDHLKELIVYADQRILILPGGGISTENVQTVMDTLKVTEVHGTKIV
What is the function of this protein?
Might participate in the control of copper homeostasis; data from other bacteria suggests it is not involved.
What are the official names of this protein?
PF03932 family protein CutC, Putative copper homeostasis protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYLIP_HUMAN
Sequence: MLCYVTRPDAVLMEVEVEAKANGEDCLNQVCRRLGIIEVDYFGLQFTGSKGESLWLNLRNRISQQMDGLAPYRLKLRVKFFVEPHLILQEQTRHIFFLHIKEALLAGHLLCSPEQAVELSALLAQTKFGDYNQNTAKYNYEELCAKELSSATLNSIVAKHKELEGTSQASAEYQVLQIVSAMENYGIEWHSVRDSEGQKLLIGVGPEGISICKDDFSPINRIAYPVVQMATQSGKNVYLTVTKESGNSIVLLFKMISTRAASGLYRAITETHAFYRCDTVTSAVMMQYSRDLKGHLASLFLNENINLGKKYVFDIKRTSKEVYDHARRALYNAGVVDLVSRNNQSPSHSPLKSSESSMNCSSCEGLSCQQTRVLQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVYLPTHTSLLNLTVI
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8.  Activity depends on E2 enzymes of the UBE2D family.  Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth.  Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
What are the official names of this protein?
E3 ubiquitin-protein ligase MYLIP, Inducible degrader of the LDL-receptor, Idol, Myosin regulatory light chain interacting protein, MIR, RING-type E3 ubiquitin transferase MYLIP.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: ENO_YERPA
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVAAVNGPIAQAVIGKDAKDQANIDKIMIDLDGTENKSQFGANAILAVSLAAAKAAAASKGMPLYEHIAELNGTPGKFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAVRIGSEVFHHLAKVLKAKGLNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEDLTKQYPIVSIEDGLDESDWAGFKYQTEVLGDKIQLVGDDLFVTNTKILKEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGDRAPFNGLKEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: LSM12_YEAST
Sequence: MSVSLEQTLGFRIKVTNVLDVVTEGRLYSFNSSNNTLTIQTTKKNQSPQNFKVIKCTFIKHLEVIGDKPSFNSFKKQQIKPSYVNVERVEKLLKESVIASKKKELLRGKGVSAEGQFIFDQIFKTIGDTKWVAKDIIILDDVKVQPPYKVEDIKVLHEGSNQSITLIQRIVERSWEQLEQDDGRKGG
What are the official names of this protein?
Protein LSM12, Sm-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the LSM12 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.