PharMolix/UniProtQA huggingface dataset:
Protein: GYRB_HELPY
Sequence: MQNYQSHSIKVLKGLEGVRKRPGMYIGDTNVGGLHHMVYEVVDNAVDESMAGFCDTINITLTDEGSCIVEDNGRGIPVDIHPTEKIPACTVVLTILHAGGKFDNDTYKVSGGLHGVGVSVVNALSKRLIMTIKKEGQIYRQEFEKGIPTSELEIIGKTKSAKESGTTIEFFPDESVMEVVEFQAGILQKRFKEMAYLNDGLKISFKEEKTQLQETYFYEDGLKQFVKDSAKKELLTPIISFKSMDEETRTSIEVALAYADDYNENTLSFVNNIKTSEGGTHEAGFKMGLSKAILQYIGNNIKTKESRPISEDIKEGLIAVVSLKMSEPLFEGQTKSKLGSSYARALVSKLVYDKIHQFLEENPNEAKIIANKALLAAKAREASKKARELTRKKDNLSVGTLPGKLADCQSKDPLESEIFLVEGDSAGGSAKQGRDRVFQAILPLKGKILNVEKSHLSKILKSEEIKNMITAFGCGIQESFDIERLRYHKIIIMTDADVDGSHIQTLLMTFFYRYLRPLIEQGHVYIAQAPLYKYKKGKTEIYLKDSVALDHFLIEHGINSVDIEGIGKNDLMNLLKVARHYRYALLELEKRYNLLEILRFLIETKDALSLDMKVLEKSILEKLEGLNYQILRSFATEESLHLHTQTPKGLVEFNLDDNLFKEVLFEEANYTYQKLMEYNLDFLENKDILAFLEEVENHAKKGANIQRYKGLGEMNPNDLWETTMHKENRSLIKLKIEDLEKTDAVFSLCMGDEVEPRRAFIQAHAKDVKQLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TR120_MOUSE
Sequence: MNLVEWIVTIIMMTEFLLGNCANVFITIVNFIDCVKRRKISSADRIITAIAIFRIGLLWAMLTNWHSHVFTPDTDNLQMRVFGGITWAITNHFTTWLGTILSMFYLFKIANFSNSLFLHLKRKLDNVLLVIFLGSSLFLVAYLGMVNIKKIAWMSIHEGNVTTKSKLKHVTSITNMLLFSLINIVPFGISLNCVLLLIYSLSKHLKNMKFYGKGCQDQSTMVHIKALQTVVSFLLLYATYSSCVIISGWSLQNAPVFLFCVTIGSFYPAGHSCILIWGNQKLKQVFLLLLRQMRC
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 120, T2R120, mT2R47.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FOLB_MYCTU
Sequence: MADRIELRGLTVHGRHGVYDHERVAGQRFVIDVTVWIDLAEAANSDDLADTYDYVRLASRAAEIVAGPPRKLIETVGAEIADHVMDDQRVHAVEVAVHKPQAPIPQTFDDVAVVIRRSRRGGRGWVVPAGGAV
What is the function of this protein?
Possible cargo protein of a type 1 encapsulin nanocompartment involved in protection against oxidative stress (Probable).  Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin, 7,8-dihydromonapterin and 7,8-dihydroxanthopterin, respectively, in equal quantities.  After longer incubation times the only product is 6-hydroxymethyl-7,8-dihydropterin (PubMed:23150985, PubMed:24855650).  Retains aldolase activity when encapsulated with a slight decrease in rate.  It is not known if this protein is normally found in the encapsulin nanocompartment (PubMed:24855650).
What are the official names of this protein?
Dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin 2'-epimerase, 7,8-dihydroneopterin aldolase, 7,8-dihydroneopterin epimerase, 7,8-dihydroneopterin hydroxylase, Dihydroneopterin epimerase, Dihydroneopterin hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
What are the subcellular locations of this protein?
Encapsulin nanocompartment. Note=Forms an approximately 6 nm diameter cargo inside the encapsulin nanocompartment, would be similar to the size of the homotetramer or homooctamer.
Protein: DCVR_CUCSA
Sequence: MSICSTVGAGLNLHSPANATNSTRLSSNFVHQIPVSSFSFSFQSSSLRLSQTPKFSRQRRNPIVVSSTPVVESTKSSFRAKNPKDTNILVVGSTGYIGNFVVKELVSRGFNVIAIAREKSGIKGRNSKEQASDQLKGANVCFSDVSHLDVLEKSLGDLDVPIDVVVSCLASRTGGIKDSWKIDYEATKNSLVAGRNRGASHFVLLSAICVQKPLLEFQRAKLKFEAELMEAAKEDSGFTYSIVRPTAFFKSLGGQVELVKDGKPYVMFGDGKLCACKPISEQDLASFIADCVLSEDKINQVLPIGGPGKALTPLEQGEILFRLLGKEPNFFKVPIGIMDFAIGVLDFLVKFFPAMEDAAEYGKIGRYYAAESMLILDPETGEYSADKTPSYGKDTLEDFFERVLSEGMAGQELGEQSVF
What is the function of this protein?
Catalyzes the conversion of divinyl chlorophyllide to monovinyl chlorophyllide.  Reduces the 8-vinyl group of the tetrapyrrole to an ethyl group using NADPH as the reductant.  The best substrate is (3,8-divinyl)-chlorophyllide a (DV-Chlidea).  Very low activity with (3,8-divinyl)-protochlorophyllide a (DV-Pchlidea) and (3,8-divinyl)-magnesium-protoporphyrin IX monomethyl ester (DV-MPE).  No activity with (3,8-divinyl)-magnesium-protoporphyrin IX (DV-Mg-Proto) and (3,8-divinyl)-chlorophyll a (DV-Chla).
What are the official names of this protein?
Divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DPS1_SCHPO
Sequence: MIQYVYLKHMRKLWSLGKVRSTVLRFSTTNRNASHLIKNELEQISPGIRQMLNSNSEFLEECSKYYTIAQGKQMRPSLVLLMSKATSLCHGIDRSVVGDKYIDDDDLRSFSTGQILPSQLRLAQITEMIHIASLLHDDVIDHANVRRGSPSSNVAFGNRRSILAGNFILARASTAMARLRNPQVTELLATVIADLVRGEFLQLKNTMDPSSLEIKQSNFDYYIEKSFLKTASLISKSCKASTILGQCSPTVATAAGEYGRCIGTAFQLMDDVLDYTSKDDTLGKAAGADLKLGLATAPVLFAWKKYPELGAMIVNRFNHPSDIQRARSLVECTDAIEQTITWAKEYIKKAKDSLLCLPDSPARKALFALADKVITRKK
What is the function of this protein?
Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.
What are the official names of this protein?
Decaprenyl-diphosphate synthase subunit 1, All-trans-decaprenyl-diphosphate synthase subunit 1, Decaprenyl pyrophosphate synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: MTND_LEPBA
Sequence: MATIVKKQETIQDKDQVKAYLTQKGLVYESYKTPESLDLILGQKGLSDAEKEEVLSGLEYRFDQLKKQHGYKANDLVVLHDEVPGISDMLAKFDKLHIHTDEEVRYIIDGSGIFGFIIDGERFEVHVGKGDFISIPANTNHWFTLDQTMRIKAVRYFKDNSGWTPVYVDESKVLINA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: FDB93_GIBM7
Sequence: MTIQSNEFNVAIVGAGVAGLALAMALHRKGVLFTIYEEAKEYSVVGAGIGFGPNGMQALDLIEPGFRPLYEGLCVGNKSADAQWVFFEGYLLEPGLGDNKPWAGNLKSAWGNQDYVRKSAHRKELLDIMTSFIPIESVKFNKKLVSIKEYTDRVMLEFADGEIVAHSILAGSDGIASTVREYLLRPTHPEEALPVYSGAHCYRAVIPMDEAYEIMGEKTDVAKIYFGHNRGAVSYRITGGKELNFLLIKATPNEQWPYPGRVTKQITQEEMLADFDGDNIDDRFRRLVAKAKPVKWGLFHHAKTSTYYKDRVCILGDSAHASMPFQAAGAAQGVEDALVLAYILEELMKSPTRGSEQLEEINAGLAAYDAIRRPRAQKQLDRAFEVGTMIYFQHPECGDDMTKILHKLQNGWLDWLWFPDLKADVETALSQMRNDVQKKA
What is the function of this protein?
FAD-dependent monooxygenase; part of the Fusarium detoxification of benzoxazolinone cluster 1 (FDB1) involved in the degradation of benzoxazolinones produced by the host plant (PubMed:19302487, PubMed:26808652).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (PubMed:11876429).  The first step in the detoxification of benzoxazolinones involves the hydrolysis of the cyclic ester bond of benzoxazolinones by the FDB1 cluster gamma-lactamase MBL1 to aminophenols (PubMed:26808652, PubMed:12788712).  MBL1 is able to convert BOA into 2-aminophenol (2-AP), as well as MBOA into 5-methoxy-2-aminophenol (2-AMP) (PubMed:26808652, PubMed:12788712).  The FDB2 cluster N-malonyltransferase FDB2/NAT1 then metabolizes aminophenols via N-malonylation to non-toxic malonamic acids (PubMed:19302487, PubMed:12788712).  FDB2/NAT1 converts 2-AP into N-(2-hydroxyphenyl) malonamic acid (HPMA) and 2-AMP into N-(2-hydroxy-4-methoxyphenyl) malonamic acid (HMPMA) (PubMed:19302487, PubMed:12788712).  The duplicated dienlactone hydrolases DLH1 and DLH2 may provide redundant function for hydrolyzing the lactone moiety in the BOA molecule (Probable).  The roles of the amidases an other enzymes encoded by the 2 FDB clusters have not been identified so far (Probable).
What are the official names of this protein?
FAD-dependent monooxygenase FVEG_08293, Fusarium detoxification of benzoxazolinone cluster 1 protein FVEG_08293, FDB1 cluster protein FVEG_08293.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MATK_GAGLU
Sequence: MEEFQEYFKKDKSPQQHFLYPLLLQEYIYTLAYDDGLNGSIFYEPIEFMGYDNKSSLVLVKRLIIRMYQQNFFIYLVNDSNQNRFRGHTNYFYSHFFYSQMVSEGFSVIVEIPFSLRLVSSPEEKEIPKSQNLRSIHSIFPFLEDKLSHLNNVSXILIPHPIHLEILVQILQCXIQDVPSLHLLRFFLHKSHNMNSFLKNNKTIHVFSKETKRLFWFLYNSYVYECEFLLVFLRKQSCYLRSTSSGAFLERSYFYGKMEHIHIIIVYCNNFHKTLWSIKDPFMQYVRYQGKAILASRGAYLMMNKWRYYLLNFWQYYLNFWSQPYRMHINPLLNYSFYFMGYLSSVLINPSAVKNQMLENSFIIDTGIHKFDTIIPVIPLIGSLSKAKFCTVSGHPISKPVWADLSDFDIIDRFGKICRNLSHYYSGSSKKQSLYRIKYILRLSCARTLARKHKSTARALLQRLGSGLLEEFFMEEEQVLSFIFPKTTLFPLHGSHRERIWSLDIIRVNDLVNQII
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR6_PHATC
Sequence: MPLLRKYEIMILLTEEFNDSELKTWVFNYAKNLRKFSVCDISVISRGKHNLAYPIETKMKGNYIQLNFSSMPKYITNFSKTLKMDSNVLRFLVFNKQL
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL2_BLOFL
Sequence: MSVIKCNPTSPGRRHVVKLVNGGLYKGKPYSSLLSKKVANSSKGRNNYGRITMRHIGSGHKQRYRIIDFKRNKDDVFAVVERMEYDPNRSANIALIVYKDGERRYILAPRNLNVGNKIISGLNVPISPGNSLPLSNIPVGSIIHNVEMKVGKGGQLARSAGTYVQIVSRDGEYIILRLRSGEIRKVRCECRATIGEVGNNEHMLRALGKAGASRWRGIRPTVRGTAMNPIDHPHGGGEGKNFGKHPVSPWGVQTKGKRTRSNKRTDKFILCRRKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GCYB1_RAT
Sequence: MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRSEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQDSRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGKCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETNQDEN
What is the function of this protein?
Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
What are the official names of this protein?
Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S11_HYDST
Sequence: MTCCNQQSSQPKTTTNCAGNSCYKKTWSDHRGTIIERGCGCPQVKSGIKLECCHTNECNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 1, Toxin A.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: 3SOFB_NAJHH
Sequence: LKCHNTQLPFIYKTCPEGKNLCFKTTLKKLPLKIPIKRGCAATCPKSSALLKVVCCSTDKCN
What is the function of this protein?
Has low cytotoxic activity.
What are the official names of this protein?
Cytotoxin 11, Toxin CM-12.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XV sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: H2A4_RAT
Sequence: MSGRAKQGGKARAKAKSRSFRAGLQFPVGRVHRLLRQGNYAERIGAGTPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKSQTK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 4, Histone H2A, testis, TH2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TGT_HERAR
Sequence: MLNFKLLNTDGNARRGQLTVNHGVIETPIFMPVGTYGSVKAMSPLELKEIDAQIILGNTFHLWLRPGNDIVAKFGGLHEFMGWDKPILTDSGGFQVFSLGEMRKITEEGVHFSSPINGDKLFLSPEVSMQIQRVLNSDIVMQFDECTPYEIDGRPATADEAAKSMRMSLRWAKRSIDEFNREENPNALFGIVQGGMFEHLRDESLAGLEDINFHGVAIGGLSVGEPKEDMLRVLQHVGPRLPANKPHYLMGVGTPEDLVQGVANGIDMFDCVMPTRNARNGWLFTRFGDIKIKNARYKDDKKPLDASCGCYACRNFSRAYLHHLHRTGEILGARLNTIHNLHYYLDLMREMREAISEGRFQLFVKQFHADRARGA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: LIMC_DICDI
Sequence: MSSICPTCTKRVYAAEAVKACEKQYHKLCLQCFHCHKILQLGQYSERDGQPYCKTDYDRLFRQAGYRGGGVVADSFEPAPKVETTTPVEPTPPPTFLTPTEEVKVQLFPTNCPKCGKKAYFNELKVYNSRDWHKTCFACFSCNKNLVSGQYSEKEGLIYCPRCYQSKFGPSGYTNTGALVLH
What is the function of this protein?
Binds to F-actin and may modulate the chemotactic response during early development and contribute to the maintenance of the strength of the actin cytoskeleton.
What are the official names of this protein?
LIM domain-containing protein C.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Protein: SPEE_THISH
Sequence: MSLDNTWFTEIHQDTAFSLRMKEKLHEEQTPFQKIEIYETEGFGTLMVIDGCVMLTDRDNFIYHEMMSHPVLYSHSDPKNVLIIGGGDCGTLREVLKHPEVKSATQVDIDERVTRLAEKYFPELCDSNDDPRAKLLFDDGIKYVQDAAPGSLDVIIIDSTDPVGPAEGLFSTAFYRDCIKALGPGGLLVQQSESPLLHTDSIIKPMHDSLRAAGFLDTLALHFPQCSYPSGWWTATMACKDMPVTFLREAQAEDKPFETHYYNAAIQRAAIACPEFFRKKLYG
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_STRP7
Sequence: MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQVYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAVMELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTVEMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREEILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAAITQEITEIVAGASALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NCL1_CAEEL
Sequence: METQLSVQLGLDSLLTDFGLESVMNKQQQLFANMGLSDIGAPTPSTAIPVPNAHLHPSMVAGSDPSNPVVGFGFGSPSSTTSSSPPLSNSPTIEQQQHAQLTAMMQGIMSNNNVAVSNGSGVQVASVPAVHCSGCKSNETATSFCQDCNANLCDNCTMAHKFMHCFADHRVVSLTTPGTGSSSSSTSSSSSASSTSSHQVPSLGGKQSPDSMMLGSGKRSVLCLQHRASELVFFCVSCNLAICRDCTVSDHPSGTHQYELIADVADKQMLKMEQLIADARSKHADMLDMFKQVDNKQQVLTASLHNAHAQLEETVSNLINVIQDQKKTLAKDIDNAFAAKQIQLTMVDKRIQSMADKLSQTIEFSRRLMSFASPAEVMVFKQLLDTRLQLFLGFNPDTSGVLMTPCEIEYLGAAGLFNNSASTVSQLLGSVHGGSPINNAPAANDFLMPQAGLAPIGRAQSRIIPIEQNQLARSPPHHIAGSLPMNAYSDSNLLRPNKDFGGSSQSLGPFNPLGASVPGAAADPFSSQYDKWSLGVEPSVGGLLEGGNVDEEKFQTLFPPSRSQIKRQKMIYHCKFGEFGVMEGQFTEPSGVAVNGQGDIVVADTNNHRIQVFDKEGRFKFQFGECGKRDGQLLYPNRVAVNRTTGDFVVTERSPTHQIQVYNQYGQFLRKFGANILQHPRGVCVDSKGRIIVVECKVMRVIIFDMFGNILQKFSCSRYLEFPNGVCTNDKNEILISDNRAHCIKVFSYEGQYLRQIGGEGVTNYPIGVGINSLGEVVVADNHNNFNLTVFSQDGTMIGALESRVKHAQCFDVALVDDGSVVLASKDYRLYLYRFLPATSGQSTSSASSQI
What is the function of this protein?
Translational repressor that inhibits protein synthesis (PubMed:9508766, PubMed:26492166).  Represses the translation of mRNAs such as fib-1, probably by being recruited by RNA-binding protein nos-2 and the Pumilio proteins puf-5, puf-8 and puf-9 to the consensus core PUF binding motif in the 3'-UTR of fib-1 mRNA (PubMed:26492166).  Negatively regulates ribosomal RNA (rRNA) synthesis, ribosomal protein synthesis and nucleolus size (PubMed:9508766, PubMed:8582642, PubMed:22768349, PubMed:26492166, PubMed:28853436).  Its role in the negative regulation of nucleolus size is most likely through its negative regulation of the translation of proteins such as the rRNA 2'-O-methyltransferase fib-1, and dao-5 (PubMed:26492166, PubMed:28853436).  Might act directly as a transcription factor to inhibit RNA polymerase I (rRNA) and III (5S RNA) transcription (PubMed:9508766).  Plays a role in embryonic development, and in particular, is involved in regulating the localization of proteins, such as par-2, that are required for embryonic cell polarity (PubMed:18652816).  Plays a role in the regulation of lifespan, and the response to nutrient availability (PubMed:28853436).
What are the official names of this protein?
B-box type zinc finger protein ncl-1.
Protein: PYRB_METS5
Sequence: MRDVISVLDFSRDEILQLFELTDKFLSGGFRPSLEGKIVATAFFEPSTRTALSFTSAALSAGAKVLGFSSDEATSVSKGENLADTIRMLENYADCIVMRHKLDGSAKFAAEVAKKPVINAGDGKREHPTQALIDMYTVRKLFGTLEGLTFGFLGDLRYARTVNSMLRILTLFKPKIVYLISPPQLRARAEILEELNYPVKELTDVKDVVGELDVLYVTRIQRERFLDEDEYEKVKESYRLDYRTVERMRKESAILHPLPRVSEIDRRIDSMPQAKYFLEASYAVPLRSVLLHEVMAGD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PHKR_MYCBP
Sequence: MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGNLAFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDLPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRGLKKL
What is the function of this protein?
Catalyzes the reduction of the keto moiety of phthiodiolone dimycocerosates (DIM B) and glycosylated phenolphthiodiolone dimycocerosates to form the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycocerosates during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis.
What are the official names of this protein?
Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase.
What is the protein family that this protein belongs to?
Belongs to the mer family. Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase subfamily.
Protein: Y1549_METJA
Sequence: MRDVAIIGYGQTKFGELWERSFRSLIVEAGVKAVEAAGIDGKDIDEMYVGNMSAGLFVGQEHIASLIAEHAGLNPIPSTRVEAACASGSLALRQAVLNVASGASDVVLVGGVEKMTDVVDATSAISSASDQEWEALFGATFPSLYAMMAQRYMYEYGLTLEELSMWSVIMHENASKNRYAQFPFKVTLEQVLNSSPVAEPLRLLHCSPVSDGAAALIVCEAEKAKEFVNKDDIIYIKASVQASDTIALHSRESITSLKAAKVASEKAYKMANIEPKDVDVAEVHDCFAINGLILMEELGFCKKGEAGKIVYDKKIAIDYDGFPAVNPSGGLKAAGHALGATGIRQVGEIYWQLKQDKEVKDRQVEIKNGYGITVNVGGTGGTVCIHILSDKR
What are the official names of this protein?
Uncharacterized protein MJ1549.
Protein: POLC7_CYNDA
Sequence: MADTGDMEHIFKRFDTNGDGKISLAELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFDEFISFCNANPGLMKDVAKVF
What are the official names of this protein?
Polcalcin Cyn d 7, Calcium-binding pollen allergen Cyn d 7, Calcium-binding protein B1.
Protein: Y1188_CALS8
Sequence: MFLEVETHCHTIASGHAYNTLEEMVAEAKNKGLKGICITDHGPEMPGSCSSLYFYNLVVVPRKIDGIMVFRGCEANIIDYEGSVDLPESALNRLDFVIASLHDVCIPPGTILDHTRALISAIKNPNILCIGHPGNPLYEIDKEAVVKTAKEHNKAIEINNASFYVREKSRENCIEILKLCKKYGVYIAMGSDAHFKTDIARCDVTRKLIEEYEFPHELIVNKSLENFLEFLRLHGKNIE
What are the official names of this protein?
Probable phosphatase Csac_1188.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: HYPD_CUPNH
Sequence: MKYIEEFRDGELAQRIAAHVRAEARPGQRYNFMEFCGGHTHAISRYGVTELLPENVRMIHGPGCPVCVLPIGRIDLALHLALERDAIVCTYGDTMRVPASGGMSLIRAKAHGADIRMVYSAADALKIAQRHPQREVVFLAIGFETTTPPTALIIREAKARQVDNFSVLCCHVLTPSAITHILESPEVRDYGTVPIDGFVGPAHVSIVIGTRPYEHFSREYGKPVVIAGFEPLDVMQAILMLVRQVNSGRAEVENEFVRAVTRDGNESAQAMVSEVFELRPSFEWRGLGEVPYSALRIRAQFARFDAEQRFDLRYRPVPDNKACECGAILRGVKKPTDCKLFATVCTPENPMGSCMVSSEGACAAHYSYGRFKDIPLVAA
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Involved in the biosynthesis of the Fe(CN)(2)CO cofactor.
What are the official names of this protein?
Hydrogenase maturation factor HypD.
What is the protein family that this protein belongs to?
Belongs to the HypD family.