PharMolix/UniProtQA huggingface dataset:
Protein: YR363_MIMIV
Sequence: MQEINGTSHLKMGIAITTYSNEKTSATRIQIIRDSLTSLKMFRNNVEVIIVVDGSYNTDHKKLLDEFNGDFEIIYREKNGGISKAKNTCIKLLLAKNIDIGFLADDDVLYCENWHNAYATSILNTKIDHFVYLPPQIYQSVLRKTTYNNIPVIECTSGGIAGCFMTFTPKIIQQIGYFRIYPYVYGCEHRDFSYRCLKNRLVPNIFDIDNSSNYLKLHHLSLDSSSIIVDKGGLALNIEKKKEYLNKFQEYVECIE
What are the official names of this protein?
Uncharacterized glycosyltransferase R363.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: RFOX3_BOVIN
Sequence: MAQPYPPAQYPPPPQNGIPAEYAPPPPHPTPDYSGQTPVPPEHGMTLYTPAQTHPEQPSSDTSTQPITGAQTVPQTDEAAQTDSQPLHPSDPTEKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKVNNATARVMTNKKTANPYTNGWKLNPVVGAVYGPEFYAVTGFPYPTTGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAALEQTLVKMPVPWAGLAPCPLPPQQTPEPAYPTSPAFPPLSCPFASRVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTM
What is the function of this protein?
Pre-mRNA alternative splicing regulator.  Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).
What are the official names of this protein?
RNA binding protein fox-1 homolog 3, Fox-1 homolog C.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: FUCA_METVS
Sequence: MDLKEFIKICHLLYDRKYVVGSGGNVSLKKDNLVYITPTGSILGFLNEEDICVVDIAGKIIKGKPTSELNMHLEIYRNKPHVNAVVHTHSMYCTAFSVLDKKLELYTPEAEIFLKKIGYVDYCPCGTLELAECVSSCNEDVLILKKHGIVTLGSTLTEAYIKTEVLEEIAKLNHIVMSFDK
What is the function of this protein?
Involved in the biosynthesis of the coenzyme F420 which requires phospholactate produced via the aldol cleavage of L-fuculose 1-phosphate and the NAD(+)-dependent oxidation of (S)-lactaldehyde.  Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and S-lactaldehyde.
What are the official names of this protein?
L-fuculose phosphate aldolase, L-fuculose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: KTHY_YERPP
Sequence: MNSKFIVIEGLEGAGKTTTRDTVVAVLRAQGINDIVFTREPGGTPLAEKLRDLIKQGIDGEVLTDKAEVLMLYAARVQLVENVIKPALARGSWVVGDRHDLSSQAYQGGGRGIDSQLMASLRDTVLGEFRPDLTLYLDLPPAVGLARARARGELDRIEQESLAFFERTRARYLELAASDASIKTIDASQPIEQVSASISQALAQWLTNQEPV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RUVA_SALHS
Sequence: MIGRLRGIILEKQPPIVLLETGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREELGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAVDLVLTSPASPTSEDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIRDALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: LSPA_STRA1
Sequence: MRKIIIPIITILLIALDQLSKLWIVKHIELNQIKEFIPNIVSLTYLRNYGAAFSILQNQQWLFTLITIFVVCVAIIYLMKHINGSYWLLISLTLIISGGLGNFIDRLRLGYVVDMVHLDFINFAIFNVADSYLTIGIICLMIALWKEESNGNHN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIC_AERHH
Sequence: MKSELTVPLARLVPWQTPAQCEPPEALLPWLLEADSMTRRLRRHNRHFSVQLFGNRSVALDADEQQLVVAEQPMGLCREVILHGDHGPAVLGWTLFAEAALQESGLRELGEQPLGERIFGDEPARRDHLQLACFEIASNPWCPAGTVWGRRSRLFLGQWPLLVHELFLPSLSCNKELE
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_BUXMI
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISPE_CLOBJ
Sequence: MLSKAHAKVNLSLDVIGKRKDGYHLLKMLMQTIDLYDLIEIKKIKKGIIIDCDREYIPKDRRNLAYKAAELFLDRYNIDSGVRIDITKNIPVAAGLAGGSTDAATVLKIMRDIFRPDISNEELKEIALDIGADVPFCIEGGTALCEGIGEKITPIKNFKNQILVLVKPNFGLSTKDVYNNLKVEKIYIHPNTTKLIQSIEEDNLKSVARNMRNVLENVTLRKYKALNSIKSNFIELGALGSMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TRMB_SHEPC
Sequence: MSEVTTAEFNEEGKYLRKIRSFVLREGRLTKGQAQAIESQWPTMGLDYSPVPLNLSEVFGREADTVLEIGFGMGASLVQMAKDAPEQNFIGIEVHKPGVGSCLSDAAIAGVTNLRVYHHDAMEVLEHAIADGSLARVQLFFPDPWHKKRHHKRRIVQAEFAELVRRKLKIGGVFHMATDWEEYSEHMLEVMNAAPGYKNQSADGTVVPRPDHRPLTKFEARGHRLGHGVWDLMFERIA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: AT1A3_HUMAN
Sequence: MGDKKDDKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VG41_HAEIN
Sequence: MKLMLETGLMFGEEAQLEVTMRELTTGDLLDAEMAAERLVMTPEGEAVLAKSPALFGYELLRRQIASVGKINGPISMRQLRSLTTEDLNRISLYAQSWESAKAEQVVSRGRLDTADQETGKDLSAVS
What are the official names of this protein?
Mu-like prophage FluMu protein gp41.
What is the protein family that this protein belongs to?
To phage Mu protein gp41.
Protein: WDR91_CHICK
Sequence: MAAATERTDELVREYLLFRGFTAALKQLDAEIKADREKGFRVDKIVEQLQQFVQSYDLAALRDYWGYLDRRLFSRLEDMYRPTVNKLKTSLYRYYLVHTVQTGRNDKAQEFFLKQASELQNQAEWKDWFVLPFLPAPDSNPTFATYFSRQWADTFIVSLHNFLSVLFQCMPVPVILNLEAECHRSSLIQEENESLRHKLFALQAESSRMKKEELEVEEAVVHHKLPAYVANMDRLGDSELDMTCSQRSTAHSLQSRGGFLSSLLSQSKKGPARPAQPSGASPTQTGSVLLGKKEPANHQSAKGKEGTASSKDGKSHFSGLVAGESSSLQQRQKRLQEHGKERRELLSKGTSQVQSAEKKADISTSEPEPCSEPQADQAETSTKMPASSTESVGVRQEQPFIVLSQEEYGEHHSSIMYCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEISIDEDMPRILSLACSPSGASFVCSAAAQSPISHMDFSVVTSGGKSMNQVPGKLLLWDTKTMKQQLQFSLEPEPIAINCTAFNHNGNLLVTGAADGIVRLFDMQQHECAMSWKAHDGEVYSVEFSYDENTVYSIGEDGKFIQWNIHKSGLKISEYALPSEATGPFVLSGYSGYKQVQFPRGRLFAFDSEGNYMLTCSSTGGVIFKLNGEDKVLESCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAQKS
What is the function of this protein?
Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes.  By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport.
What are the official names of this protein?
WD repeat-containing protein 91.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR91 family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein. Late endosome membrane.
Protein: FABA_SHESW
Sequence: MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMIDRIVTINDNGGEFGKGEIVAELDINPELWFFDCHFISDPVMPGCLGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDLKVGVFSDTSTF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_BRUSU
Sequence: MGSCGGKHTGKGAPKPYSRNFTDPWRKTPGRLFGTALIRFYQITLSSLIGNSCRHLPTCSEYAYEAIARHGLWRGGWMGFFRVVRCGPFGTHGFDPVPRELSPDLKWYMPWRYWRCSASRTGK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RUTB_CAUST
Sequence: MSSPITPLSPGCVMLPARPEPVPVDPKTTAVIVIDMQNAYASPGGYLDLAGFDISGAAKVIHEIKGVLEVARSAGMQVIYFQNGWDDQYVEAGGPGSPNWWKSNALKTMRAKPELQGKLLARGQWDYELVDELKPQPGDIQLHKTRYSGFFNSQLDSVLRARGIRHLVFVGIATNVCVESTLRDGFFLEYFGTVLEDATHQAGPEFVQKAALFNIESFFGWVSTTADFKGTFGQLAPRT
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: PTBP2_HUMAN
Sequence: MDGIVTEVAVGVKRGSDELLSGSVLSSPNSNMSSMVVTANGNDSKKFKGEDKMDGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQAVLQAVTAVQTANTPLSGTTVSESAVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAGRVGMPGVSAGGNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI
What is the function of this protein?
Reduced affinity for RNA.
What are the official names of this protein?
Polypyrimidine tract-binding protein 2, Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB, PTB-like protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS6_KLULA
Sequence: MKLNISYPINGTQKCIEIDDEHRVRVFYDKRIGQEVDGESVGDEFKGYVFKIAGGNDKQGFPMKQGVLLPTRVKLLLAKGHSCYRPRRNGERKRKSVRGAIVGPDLAVLALIITKKGEQEIEGITNDTVPKRLGPKRANNIRKFFGLTKEDDVRDYVIRREVTKGDKSYTKAPKIQRLVTPQRLQRKRQQKSLKIKNAQAQREAAAEYAQLLAKRLSERKAEKAEVRKRRASSLKA
What are the official names of this protein?
40S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: TGB3_POPMV
Sequence: MWSDSLVSRICVPIIVVCTSIALLNVVSFRSECSCVVHISGAAIDIRGCSFTPDFIEYAKTLRVFNHRYQE
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata.  May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity).
What are the official names of this protein?
Movement protein TGBp3, 7 kDa protein, Triple gene block 3 protein, TGBp3.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp3 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: RRF_MYCUA
Sequence: MIDEALFDAEEKMEKAVSVAREDMATIRTGRANPGMFSRIVIDYYGTHTPITQLASINVPEARMVVIKPYEANQLHAIETAIRNSDLGVNPTNDGTIIRVAVPQLTEERRRDLVKQAKHKGEEARVSVRNIRRKAMEELHRIRKDGEAGEDEVARAEKDLDKSTHQYVAQIDELVKHKEGDLLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRA4_MOUSE
Sequence: MTTLVPASLFLLLWTLPGKVLLSVALAKEDVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLMFEWLEDAPAVQVAEGLTLPQFILRDEKDLGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRRRQRRQRMEEDIIRESRFYFRGYGLGHCLQARDGGPMEGSSIYSPQPPTPLLKEGETMRKLYVDRAKRIDTISRAVFPFTFLVFNIFYWVVYKVLRSEDIHQAL
What is the function of this protein?
Glycine receptors are ligand-gated chloride channels.  Channel opening is triggered by extracellular glycine.  Channel opening is also triggered by taurine and beta-alanine (PubMed:10762330).  Plays a role in the down-regulation of neuronal excitability.  Contributes to the generation of inhibitory postsynaptic currents (Probable).
What are the official names of this protein?
Glycine receptor subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA4 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Synapse. Perikaryon. Cell projection, dendrite. Cell membrane; Multi-pass membrane protein.
Protein: SCPA_XYLFA
Sequence: MNSERAQVANPPTQTPVPQQQEIPLAMVHGQPVLQIPQDLYIPPDALEVILDAFEGPLDLLLYLIRRQNLNILDIPVAEITRQYVDYINVMQELRFELAAEYLVMAAILAEIKSRMLLPRPPNIENEEGEDPRAELVRRLQEYERFKQAAEDLDALPRLDRDNSAAHAFVADQTTVRIPPPVNMKELLLALQDVLKRAELFSGHAIRREALSVRQRMGDILAHLEDGKFHPFTTLFTAEEGKLGVLVTFLAILELAKEQLLDIVQEASLGPIYIKSLAIHHTNGPLQLSSDFDNSPSTHAPP
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: DNAK_YERPS
Sequence: MGKIIGIDLGTTNSCVAIMDGTKARVLENSEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEAQRDKDIMPYKIIAADNGDAWLEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGMDLRTDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADGSGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIQDVILVGGQTRMPMVQKKVADFFGKEPRKDVNPDEAVAIGAAVQGGVLSGEVKDVLLLDVTPLSLGIETMGGVMTPLITKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAQDNKSLGQFNLDGIQPAPRGMAQIEVTFDIDADGILHVSAKDKNTGREQKITIKASSGLNEEEIQKMVRDAEANAEADRKFEELVQTRNQADHLIHGTRKQLEEAGDKLPAEDKTAIEEAMKGLEAALKGEDKAEIEAKTQALVQVSGKLLEMAQQQQAAAGGDAGDTSAKKEDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: XNI_YERPA
Sequence: MQIHLLIVDALNLIRRIHAVQGSPCVKACQHALQQLIQHSQPSHAVAVFDEDDRSDSWRHQCLPDYKAGRSPMPDNLQQEMPLIRQAFNELGVACWHSPGNEADDLAATLVVKVAGAGHQVTIVSTDKGYCQLLAPNIQIRDYFQKRWLDMPFVKQEFGVLPRQLPDYWGLAGISSSKIPGVAGVGAKTATLLLQQADTLEVLYQNLESIPECQRRMKSDPLISPPTAQY
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment (By similarity).
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: RLMF_ECOUT
Sequence: MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLR31_ARATH
Sequence: MLSSMNWVLLSFIIVLGGGLLLSEGASSSRPPVIKVGAIFGLNTMYGETANIAFKAAEEDVNSDPSFLGGSKLRILMNDAKRSGFLSIMGALQFMETDVVAIIGPQTSIMAHVLSHLANELTVPMLSFTALDPTLSPLQFPFFVQTAPSDLFLMRAIAEMITYYGWSDVVALYNDDDNSRNGVTALGDELEERRCKISYKAVLPLDVVITSPVEIIEELIKIRGMESRVIVVNTFPNTGKMIFKEAERLGMMEKGYVWIATTWLSSVLDSNLPLDTKLVNGVLTLRLHTPDSRKKRDFAARWKNKLSNNKTIGLNVYGLYAYDTVWIIARAVKTLLEAGGNLSFSNDAKLGSLKGEALNLSALSRFDQGSQLLDYIVHTKMSGLTGPVQFHPDRSMLQPSYDIINLVDDRVHQIGYWSNYSGLSIVPPESFYSKPPNRSSSNQHLNSVTWPGGTSVTPRGWIFRNNGRRLRIGVPDRASFKDFVSRVNGSSNKVQGYCIDVFEAAVKLLSYPVPHEFIFFGDGLTNPNYNELVNKVTTGVDFDAVVGDIAIVTKRTRIVDFTQPYIESGLVVVAPVTRLNENPWAFLRPFTLPMWAVTASFFVIVGAAIWILEHRINDEFRGPPRRQIITILWFTFSTMFFSHRETTVSTLGRMVLLIWLFVVLIITSSYTASLTSILTVQQLNSPIKGVDTLISSTGRIGFQVGSFAENYMTDELNIASSRLVPLASPEEYANALQNGTVAAIVDERPYIDLFLSDYCKFAIRGQEFTRCGWGFAFPRDSPLAVDMSTAILGLSETGELQKIHDRWLSKSNCSSPHGSQSGDSEQLNVHSFWGMFLVVGIACLVALFIHFFKIIRDFCKDTPEVVVEEAIPSPKSSRLTKLQTFLAFVDEKEEETKRRLKRKRNNDHSMNANSIISRTASRRPI
What is the function of this protein?
Glutamate-gated receptor that probably acts as non-selective cation channel.  May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.  Required for the long-term calcium oscillation-regulated stomatal movements.
What are the official names of this protein?
Glutamate receptor 3.1, AtGLR2, Ligand-gated ion channel 3.1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CAB45_CHICK
Sequence: MMSRQAFLCSLGSLYLSLLFVFLLMDVYARPANNSALKEKPADSRDENEILPPDHLNGVKMEMDGHLNKEFHQEVFLGKEMEEFEEDSEPRKNRKKLMVIFSKVDIDNDKKISAKEMQRWIMEKTDEHFQEAVEENKMHFRAVDPDGDGHVSWDEYKIKFLASKGLNEKEIAEKIKNNEELKIDEETQEVLDNLKDRWYQADNPPPDMLLNEEEFLSFLHPEHSRGMLKFMVKEIIRDLDQDGDKKLTLSEFISLPVGTVENQQAQDIDDDWVKDRRKEFEDVIDANHDGIVTMEELEEYMDPMNEYNALNEAKQMIAVADENQNHHLELEEILKYSEYFTGSKLMDYARNVHEEF
What is the function of this protein?
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
What are the official names of this protein?
45 kDa calcium-binding protein, Cab45, Stromal cell-derived factor 4, SDF-4.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Golgi apparatus lumen.
Protein: Y1185_SOLUE
Sequence: MDWQLDAAELRVLGALMEKEATTPDYYPMSLNALVNACNQKSNREPVVNFDEETVETALHELRAKGLSSRISGESRVPKHEQRFVEKFNLGRREAAVMCVLMLRGPQTVGELRGRTERIFTFDDLEGVESTLQRLAEIGFVKKLPRQTGYKEQRWAQLLAGDIEVAEEAAPAMMERGASDRDRIAALEEEVAELKRAFEQFRRNFE
What are the official names of this protein?
UPF0502 protein Acid_1185.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: OTUD5_HUMAN
Sequence: MTILPKKKPPPPDADPANEPPPPGPMPPAPRRGGGVGVGGGGTGVGGGDRDRDSGVVGARPRASPPPQGPLPGPPGALHRWALAVPPGAVAGPRPQQASPPPCGGPGGPGGGPGDALGAAAAGVGAAGVVVGVGGAVGVGGCCSGPGHSKRRRQAPGVGAVGGGSPEREEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQYSTGTSAVEPINTFHGIHQNEDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPSFKPGFAEQSLMKNAIKTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQVRGPSQPRKASATCSSATAAASSGLEEWTSRSPRQRSSASSPEHPELHAELGMKPPSPGTVLALAKPPSPCAPGTSSQFSAGADRATSPLVSLYPALECRALIQQMSPSAFGLNDWDDDEILASVLAVSQQEYLDSMKKNKVHRDPPPDKS
What is the function of this protein?
Deubiquitinating enzyme that functions as negative regulator of the innate immune system.  Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production.  Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro).  Controls neuroectodermal differentiation through cleaving 'Lys-48'-linked ubiquitin chains to counteract degradation of select chromatin regulators such as ARID1A, HDAC2 and HCF1 (PubMed:33523931).
What are the official names of this protein?
OTU domain-containing protein 5, Deubiquitinating enzyme A, DUBA.
What is the protein family that this protein belongs to?
Belongs to the peptidase C85 family.