PharMolix/UniProtQA huggingface dataset:
Protein: UGPC_VIBCH
Sequence: MLDIKQLVKTYDNGHQAVKGVDLSIHQGEFIVLVGPSGCGKSSILRSIAGLESITSGEIHLAGRRVDNEKPANRDIAMVFQNYALYPHMSVYDNLAYGLKNRGVDKQTIAAKIAKVAKTLKIEEYLDRKPAKLSGGQRQRVAMGRAIVRDPQLFLFDEPLSNLDAALRAHMRLEIKKLQRELGVTSVYVTHDQVEAMTLADRIVVVKQGEIEQVGTPAEVYHQPASTFVASFIGSPAMNFLPASIKQGQLHIAGKHCYLPQFDAMSSENITLGIRPEHASLHPLTNAIELKLDIQVVEPLGPNQLVHGKIIGLESEQDFIAVTAEIPLDVHQTLPIWVALEQLHLFDQQGKRFVQSHRSCTQSSKVASTRQQ
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TPS5_PSEAD
Sequence: MAGVSVESKVSSLVCNLSSTSGLIRRTANPHPNVWGYDFVHSLKSPYTDSSYRERADALVVEIKAMLNAAIAGDGESTITPSAYDTAWVARVPAIDGSARPQFPQTVDWILKNQLKDGSWGIESHFLLSDRLLATLSCVIALFKWNVGDLQVKQGIEFIKSNLELVKDESDQDSLVTDFEIIFPSLLREAQSLSLELPYDLPYIHLLQTKRQERLAKVSREEIYTVPSPLLYSLEGIQDIVEWDRIMDVQGQDGSFLSSPASTACVFIDVKCLEFLNNVMMKLGNFVPCLYPVDLLERLLIVDNIERLGIYRHFEKEINEALDYVYRHWNERGIGWGTRNPIADLETTALGFLLLRLHRYNVSPAVFDNFKDSNGQFFCSTGQLNKDVASMLSLYRASQLAFPGEDILDEAKSFTTKYLREALEKSETSSAWNNKQNLSQEIKYALKTSWHASVARVEAKRYCQVYRPDYARLAKSVYRLPYVNNEKFLELGKLDFNIIQAIHQEEMKTVTSWFRDSGLPLFTFARERPLEFYFLVATGTYEPQYAKCRFLFTKVACLQTVLDDMYDTYGTLDELKLFTEAVRRWDLSFTENLPDYMKLCYKIYYDIVHEVAWEAEKEQGRELVSFFRKGWEDYLLGYYEEAEWLASEYVPSLDEYIKNGITSIGQRILLLSGVLIMDGQLLSQEALEKVDYPGRRVLTELNSLISRLADDTKTYKAEKARGELASSIECYMKDHPECTEEEALAHIYSILEPAVKELTREFLKPDDVPFACKKMLFEETRVTMVIFKDGDGFGVSKLEVKDHIKESLIDPLPL
What is the function of this protein?
Converts farnesyl diphosphate to alpha-bisabolene (PubMed:28096378).  Involved in defensive oleoresin formation in conifers in response to insect attack or other injury (By similarity).  Involved in sesquiterpene (C15) olefins biosynthesis (By similarity).
What are the official names of this protein?
Alpha-bisabolene synthase, Terpene synthase 5, PxaTPS5.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
Protein: RUTF_ECOSE
Sequence: MSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: VE1_HPV29
Sequence: MADNSGTEGEEEDCSEAERAGGWFMVEAIVDRRTGDTISSDEDEEDEGEDMVDFIDDRPIGDGQEVAQELLLQQAAADDDEAVHTVKRKFAPSPYFSPVCVPSIEHELSPRLDAIKLGRQSSKAKRRLFQLPDSGYGQTQVDTDTGPSQVQDGCETGDQNGRQQYKEGSGTKDGENGSQEEERAGGDGEESQPLSTETEKGACGVLSILKASNQKATLLGKFKEQFGLGYNELVRHFKSSRTACVDWVVCVFGVYCTVAEGIKQLIQPLCEYAHIQVLPCQWGMTVLMLVRYKRAKNRETVAKGLSTLLNVPESHMLIEPPKLRSSPAALYWYKTSMSNISDVYGETPEWIVRQTMVGHALQEVQFSLSEMVQWAYDHDITDEGTLAYEYALIADVDSNAAAFLASNCQAKYVKDACTMCRHYKRGEQARMSMSEWIRFRSNKVQGEGDWKPIVHFLRYQNVEFIPFLCAFKLFLQGIPKKSCLVFYGPADTGKSYFCMSLLKFMGGVVISYANSHSHFWLQPLSEAKMGLLDDATSQCWSYVDTYLRNALDGNVMCIDRKHRSLLQLKCPPLLITTNVNPLEDDRWKYLRSRLQVFTFSNPCPLTSKGEPVYTLNDQNWKSFFQRLWARLSLTDPDDEEENGEPSEPFRCVPGQNTRTV
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: FOLD_LISMO
Sequence: MGEIIDGKKLAKEIQEKVTREVAELVKEGKQPGLAVVLVGDNQASRTYVRNKQKRTEEAGMKSVLIELPENVTEEKLLSVVEELNEDKTIHGILVQLPLPEHISEEKVIDTISFDKDVDGFHPVNVGNLFIGKDSFVPCTPAGIIELIKSTGTQIEGKRAVVIGRSNIVGKPVAQLLLNENATVTIAHSRTKDLPQVAKEADILVVATGLAKFVKKDYIKPGAIVIDVGMDRDENNKLCGDVDFDDVVQEAGFITPVPGGVGPMTITMLLANTLKAAKRIWKMN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CHSB_IPOCO
Sequence: MCTTVTVLTDTWSRREKRFEGHAKILAIGTATPANWVDQTTYPDFYFRITNSQHLLDHKEKFRRICNKSKIRKRHMILTEELLKKNPNLCTYNDASLNTRQDILVSEVPKLGKEAAMKAIKEWGRPISEITHLVFCTTSGVDMPGADFQLTKLLGLNSSVKRLMMYQQGCNAGAAMLRLAKDVAENNKGARVLVVCSEVMLSVFRGPSLQQEDNLLAQCLFGDGSAALIVGTDPRPGLETPLFELISAAQTIIPNTDSHLKLHVREMGLTFHCSKAVPTFITQNVEDCLVKAFEPYGISDWNSIFWVLHPGGNAIVDGVEETLGLAPEKLRASRDVLSGYGNLTSACVLFILDEVRKKSKKDE
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase B, Naringenin-chalcone synthase B, CHS-B.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RPOY_LISW6
Sequence: MIFKVFYQETLKETPVREKTQSLYVEAESEVKVRQLLKDEPFHIEFVEKISDAHLAYEKENPDFALWEK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: TTGA_PSEPK
Sequence: MQFKPAVTALVSAVALATLLSGCKKEEAAPAAQAPQVGVVTIQPQAFTLTSELPGRTSAYRVAEVRPQVNGIILKRLFKEGSEVKEGQQLYQIDPAVYEATLANAKANLLATRSLAERYKQLIDEQAVSKQEYDDANAKRLQAEASLKSAQIDLRYTKVLAPISGRIGRSSFTEGALVSNGQTDAMATIQQLDPIYVDVTQSTAELLKLRRDLESGQLQKAGDNAASVQLVLEDGSLFKQEGRLEFSEVAVDETTGSVTLRALFPNPDHTLLPGMFVHARLKAGVNANAILAPQQGVTRDLKGAPTALVVNQENKVELRQLKASRTLGSDWLIEEGLNPGDRLITEGLQYVRPGVEVKVSDATNVKKPAGPDQANAAKADAKAE
What is the function of this protein?
Probable periplasmic linker protein component of the TtgABC efflux pump with unknown specificity.
What are the official names of this protein?
Probable efflux pump periplasmic linker TtgA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: ATPB_DEHMC
Sequence: MANGKVIQVIGSVVDVEFSADSMPALFNALEIPRENGKMVLEVQSHVGNNRVKCLSFTPTDGLERGAEVIDTTRPLSVPVGRGTLGRIFNVLGEALDNRGDVKSEKTMPIHRLAPGMDELESSAQVLETGIKVIDLIAPFARGGKIGALGGAGVGKTVLIQELIRNIATEHEGFSVFAGVGERSREGNDLWHEMEDSGVLPKTTMVFGQMNELPAVRLRIALTGLTMAEYFRDEERQDVLLFIDNIYRYTLAGMEVSALLGRMPSAVGYQPTLATEMGALQERIASTKQGSITSFQAVYVPADDYTDPGVVATFGHLDAMIALERSLAEQALYPAVDPLASNSRILDPQVVGEEHYKVARDVQKVLQRYKDLQDVIAILGMEELSEEDKLTVARARRIQRFLTQPMFVSEVFTGRPGQYVSLTETIRGFKEILEGKHDSLPEQAFYMVGTIDDAVAEAKKLSAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PT525_ARATH
Sequence: MGKGGSLSEGVIKNIIISYTYVAIWIFLSFTVIVYNKYILDKKMYDWPFPISLTMIHMSFCSTLAFLLIKVFKFVEPVSMSRDTYLRSVVPIGALYSLSLWLSNSAYIYLSVSFIQMLKALMPVAVYSIGVLFKKEGFKSETMMNMLSISFGVAIAAYGEARFDVWGVILQLGAVAFEATRLVMIQILLTSKGITLNPITSLYYVAPCCLAFLFIPWIVVEFPILRDTSSFHFDYLIFGTNSFCAFALNLAVFLLVGKTSALTMNVAGVVKDWLLIAFSWSVIKDTVTPINLFGYGIAFLGVAYYNHAKLQALKAKEAQKTAQQVDEETGRLLEEREGNEGGRKNEPED
What are the official names of this protein?
Probable sugar phosphate/phosphate translocator At5g25400.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LYTS_BACCR
Sequence: MLNLVLMMIERVGLIVILGFLLSHIKTFRRLLHKQDGYVDKLKLICIFSVFTIVSNYTGIEIAGNTIMNENWLQGVSSSSTIANTRIMGVGISGLLGGPIVGIGVGSIAGIHRYMLGGTTALSCAISSILAGVITGYIGYIFKKYNRTITPKFSAILSVFIVSLEMIMILLIVEDGMSIVKTIAIPMILVNSFGSFILLSMIQAILRQEENAKALQTHKVLRIADKTLPYFRQGLTEESCKHVAQIIHRFPGTDAVSLTDTEKILAHVGLASDHHIPSHSLITGLSKEVLHTGQIMKAKSREVINCQHEGCPLQAAIVIPLTSHGNTIGTLKLYFKNPNQLSRVEEELAEGLAKIFSTQLELGEAELQSKLLQDAEIKALQAQINPHFLFNAINTVSALCRTDVEKARKLLLQLSVYFRCNLQGARQLLIPLEQELNHVQAYLSLEQARFPNKYEVKMYIEDELKTTLVPPFVLQLLVENALRHAFPKKQPVCEVEVHVFEKEGMVHFEVKDNGQGIEEERLEQLGKMVVSSKKGTGTALYNINERLIGLFGKETMLHIESELNEGTEITFVIPKKVGEEEQIVKSISS
What is the function of this protein?
Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.
What are the official names of this protein?
Sensor protein LytS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL27_YERPA
Sequence: MAHKKAGGSTRNGRDSESKRLGVKRFGGEAVLAGSIIVRQRGTKFHAGINVGCGKDHTLFALADGKVKFEVKGPKNRKFISIEAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: HEM1_PSEFS
Sequence: MAFLALGINHKTASVDVRERVAFTPEQLVEALQQLCRLTDSREAAILSTCNRSELYIEQEHLSADVVLRWLADYHHLDLDDLRASAYVHEDDAAVRHMMRVASGLDSLVLGEPQILGQMKSAYAVAREAGTVGPLLGRLFQATFNSAKQVRTDTAIGENPVSVAFAAVSLAKQIFSDLQRSQALLIGAGETITLVARHLHDLGVKRIVVANRTLERASILAEQFGAHAVLLADIPAELVRSDIVISSTASQLPILGKGAVESALKLRKHKPIFMVDIAVPRDIEPEVGELDDVYLYSVDDLHEVVAENLKSRQGAAQAAEEMVSAGADDFMVRLRELAAVDVLKAYRQQGERLRDEELLKAQRLLANGSSAEDVLVQLARGLTNKLLHAPSVQLKKLTAEGRLDALAMAQELFALGEGASDSSSDKKLQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: 4HYPE_RHIEC
Sequence: MRWKRTIQLLDVHAEGEIGRVAIGGVPKIPGETIAAQLHWLNTDPKGDELRRFLCLEPRGAPIGSVNLLLPARHPDADAAFIILQPDQAHASSGSNSICVTTALLESGIVEMQEPETIVTLETAAGLVKATATCRDGRCEKVKLTMVPSFVHELDVEIDTPHWGKIKADLCYGGIFYALVDVGQINLTIEKANAAGLVQAGMILKELINRDIKVVHPEIPAISGVAYVMFRDTEADGTVRTCTTMWPGRADRSPCGTGNSANLATLHARGKAKVGDVFTSKSIIGSEFEVGLQAVTEVAGRPAVIPTITGRGFTFGLTQVALDPFDPHPGGFALTDVWGPSAGEI
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  May be involved in a degradation pathway of t4LHyp.  Can also catalyze the epimerization of trans-3-hydroxy-L-proline (t3LHyp) to cis-3-hydroxy-D-proline (c3DHyp) in vitro, albeit with 2-fold lower efficiency.  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase, 4Hyp 2-epimerase, 4HypE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: RLMN_CLOPE
Sequence: MKNILDFTLEELKEWMKENGESAFRAKQIFDWIYKKEVFNFEEMKNISKALIGKLSENFYIGIPEVIDYLSSSEDGTRKILLGLGDGNIIECVIMRYKYGNSICVSTQIGCRMGCKFCASTLEGMVRNLTAGEILSEVLIGQKLLGERISNIVLMGSGEPLDNYDNVMKFLELVNADYGLNIGQRHITLSTCGLVPKIREMADKEMQVTLAISLHAVSDEKRKTIMPIANKYSISEILDACNYYIEKTGRRITFEYSLVSGVNDTKEDAKSLGRLLKGMLCHVNLIPVNEIKENEFKKSTKKDIETFLNTLKTYGVEATVRREMGSDINAACGQLRRSYIKSKGLKL
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBF_ZAMFU
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PYRE_METMJ
Sequence: MVNPIATLLLECGAIEFGEFVLASGARSSYYIDIKAATTNPAVLTEIGKTIAEGREFEMVAGVAVGAVPIAVAVSLASGRPYAVVRKEGKDHGKAGTIIGDVLGKNVLLVEDVTTSGGSALYGLEALRAAGAHVDQVVTVVDREAGAREALAEKGASLLALVRVSELLDG
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: KAD_SINMW
Sequence: MRLIFLGPPGAGKGTQAKHLTERYGIPQLSTGDMLRAAVAQATEVGKRAKAVMDAGQLVSDEIVNEIVSDRIDAPDCAKGFILDGYPRTVPQAVALDRMLEEKNLKLDAVIELKVDEAALVRRMENRVAETVAAGGTVRSDDNPEAFRRRLQEYREKTAPLSEHYARTGRLKTVDGMADVKTVTAEIEKILA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_PSEPF
Sequence: MSRLLLNCDIGESFGSWTMGLDAEVMPFIDCANIACGFHAGDPSIMRKTVSLALSHGVKIGAHPAYQDLVGFGRRSMAYTAQELQDILHYQIGALDGICRAQGGKVSYVKPHGAMYNDMMANPAQLRAVIQAVVAYDRSLPLMLMATRDNTAAQQLGDEYGVTLWFEAFADRAYDSAGRLVSRQLPGAVHHDCETIIGQALTIARGDNLTASDGSALHLQANTLCVHGDNASSVAAVQRIRQALNEQSAP
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: YAO3_SCHPO
Sequence: MTEISELASSSQKPEKTKYNLPKPLPAYYPHPGSPLYADKELYARIANAPKKLVGRHVCQPRTGLAVKIPQKSIFSIVVPEGPQVCDLNIWNFHNPRERFWAARTRQIHSAHVSTYDRLWSTLPYLRPLVTIIGDSLQARHDEWGGRVHDTLGTRCDPYIDKLISGKDNDLHCHSNLTRAIMPYGLTEFDVHDVLNVFQVTGLNEYDQYFMETCPATSKDYFQCFAEQDLLVAISACPGGDLSNWGWGEDATDVESSKMVDCCRPLAIEVYELEDEENSLKGWVPPQVVNYTGNHGLKAPSS
What are the official names of this protein?
Uncharacterized protein C11D3.03c.
Protein: TAF9B_HUMAN
Sequence: MESGKMAPPKNAPRDALVMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKPNVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQKNQTPLPLIKPYAGPRLPPDRYCLTAPNYRLKSLIKKGPNQGRLVPRLSVGAVSSKPTTPTIATPQTVSVPNKVATPMSVTSQRFTVQIPPSQSTPVKPVPATTAVQNVLINPSMIGPKNILITTNMVSSQNTANEANPLKRKHEDDDDNDIM
What is the function of this protein?
Essential for cell viability.  TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes.  May have a role in gene regulation associated with apoptosis.  TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex.  TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 9B, Neuronal cell death-related protein 7, DN-7, Transcription initiation factor TFIID subunit 9-like, Transcription-associated factor TAFII31L.
What is the protein family that this protein belongs to?
Belongs to the TAF9 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZIPA_SHIFL
Sequence: MQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYLPPYASAQPRQPVQQPPEAQVPPQHAPRPAQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: FMAE_DICNO
Sequence: MKSLQKGFTLIELMIVVAIIGILAAFAIPAYNDYIARSQAAEGLTLADGLKIRIADHLENGSCTEDANAGAGEKGNQDTGKYALAEIGGTYAQDATNLKPEDKNGCTVTITYGKGTAGAKISKLIDTKVLELEQLVNGSYTQGGATTLDAKFIPNAVKATK
What are the official names of this protein?
Fimbrial protein, Pilin, Serogroup E2.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: SGCG_HUMAN
Sequence: MVREQYTTATEGICIERPENQYVYKIGIYGWRKRCLYLFVLLLLIILVVNLALTIWILKVMWFSPAGMGHLCVTKDGLRLEGESEFLFPLYAKEIHSRVDSSLLLQSTQNVTVNARNSEGEVTGRLKVGPKMVEVQNQQFQINSNDGKPLFTVDEKEVVVGTDKLRVTGPEGALFEHSVETPLVRADPFQDLRLESPTRSLSMDAPRGVHIQAHAGKIEALSQMDILFHSSDGMLVLDAETVCLPKLVQGTWGPSGSSQSLYEICVCPDGKLYLSVAGVSTTCQEHNHICL
What is the function of this protein?
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
What are the official names of this protein?
Gamma-sarcoglycan, Gamma-SG, 35 kDa dystrophin-associated glycoprotein, 35DAG.
What is the protein family that this protein belongs to?
Belongs to the sarcoglycan beta/delta/gamma/zeta family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Single- pass type II membrane protein. Cytoplasm, cytoskeleton.
Protein: ERCC3_DANRE
Sequence: MGRKDKSDREKKSKKRYYEDEEEDEEVIGGESQEAVPAAAGKQVDESSTKLDEYGAKDYRLQMLLKNDHSSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAISEPVCRPTHAHEYKLTAYSLYAAVSVGLQTSDIIEYLQKLSKTSVPDGIVQFIKLCTVSYGKVKLVLKHNRYFVESAFPDVIQRLLQDTVIRDCRLRSAEGEETELITETISSKSAISKSQQDNGGPSSSQPADGQRSGTQVPEDIFSYYEQMDKEEEEEEETQTVSFEIRQEMIEELQKRCIQLEYPLLAEYDFRNDTVNPDINMDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSSVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWMKSQEWGLIILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIRFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAYFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLMFSTRDEQQQLLQKVLAASDLDAEEEVVMGEVGGKPQFSRRAGTMSSMSGADDALYMEYQMPRGSKASVGKNIHPLFKRFRK
What is the function of this protein?
ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  The ATPase activity of XPB/ERCC3, but not its helicase activity, is required for DNA opening.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  The ATP-dependent helicase activity of XPB/ERCC3 is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH helicase subunit XPB, TFIIH subunit XPB, DNA excision repair protein ERCC-3.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD25/XPB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SC61A_GADOC
Sequence: MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPSEMGAGICLVIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGTEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSTGGPARAYPVGGLCYYFSPPESFGSVLDDPVHASIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEMGSMGALLF
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.  May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins.  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER).