PharMolix/UniProtQA huggingface dataset:
Protein: MCR1_NEOFI
Sequence: MFARQSLRFAQPLKQGFRKYSTEAPSKGKSSLAPIYVAVGLTGLGVGLYRYNSASAEAPPAERPKVFTGGDQGWVDLKLAQIENLSPNTKRLRFEFPDKEAVSGLHVASALLTKFKPHGAEKPVIRPYTPVSDEEQPGYLDLVVKVYPNGPMSEHLHSMNVDQRLEFKGPIPKYPWEANKHKHICLIAGGTGITPMYQLARKIFKDPEDQTKVTLVFGNVREEDILLKKELQELENTYPRRFRAFYVLDHPPKEWTGGKGYITKELLKTVLPEPKEENIKIFVCGPPGMYKSISGPKVSPKDQGELTGILAELGYSKDQVFKF
What is the function of this protein?
May mediate the reduction of outer membrane cytochrome b5.
What are the official names of this protein?
NADH-cytochrome b5 reductase 2, Mitochondrial cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: CLPB_DESVH
Sequence: MDIGKFTEKSQQALAEAQNIAVRFGHQEVDAEHLADALVRQEQGLVPRLLDRMGQKPEAFAEALERELGKRPAVSGPGAAPGQIFVSKRLNAVLVKAQDFARQLKDEYVSVEHIFCVLLEEPASTIMGRIAREFSLSREKVLGVLEDVRGSQRVTSANPEDTYEALQKYGRDLVEEARKGKLDPVIGRDAEIRRVIRILSRRTKNNPVLIGEAGVGKTAIVEGLAHRILKGDVPEGLKERGLFALDMGALIAGAKYRGEFEERLKAVLKEVEKSEGRIIMFIDELHTIVGAGKTDGAMDASNLLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQPVLVDEPTIEDAISILRGLKERFEVHHGVRISDSAIVEAVTLSHRYITDRQLPDKAIDLIDEAAALIRTEIDSLPADLDEANRKIMQLEIEREALRRETDVASRERLERLENELADLRAEQTALLSQWEREKGSIDHVRSIKEDIERTRHAIEEAERAYDLNRAAELKYSRLLELERQLESAEKGGHDETRLLKEEVRPDDIAEIVARWTGIPVTRLLESEREKLLRLADVLHERVVGQEEAVDAVSEAVLRARAGLSDPSRPIGSFIFLGPTGVGKTELCKTLAEALFDTEENIVRLDMSEYMEKHAVARLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLFDEVEKAHPDVFNTLLQILDDGRLTDSHGRTVDFRNTIIIMTSNIGSPYMLDGISEGGEFLSGVREKVMEELRRHFRPEFLNRVDETVLFKPLLPAQIARIVELLLGRLRGRLAERKIDIRLGDVARDFIAKAAYDPVYGARPLRRYLQHNIETPLARKLIAGELRDGTTVEVDVVDDALSFRIE
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT_BIFLO
Sequence: MSMAFENVDYTSLDIPAAPFSDPARIPDFPKNKVPRHIGVIMDGNGRWAKQRGMVRTNGHQAAEPVVFDTIAGAIEAGVRYLSLYTFSTENWKRSPQEVRFLMGFSREIIHRRVEQMDEWGVRVRWSGRRPKLWKSVIDELEAAEERTKNNKVIDVVFCINYGGRAEIADACAAIAREVRDGKISGDRVTEKMIADHLYNPDIPDCDLVIRTSGEQRTSNFLPWEAAYAELDFVPELFPDCGRDVLWRSIDHYIHRDRRFGGVK
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: YQKF_BACSU
Sequence: MRKRKLGTSDLDISEVGLGCMSLGTEKNKALSILDEAIELGINYLDTADLYDRGRNEEIVGDAIQNRRHDIILATKAGNRWDDGSEGWYWDPSKAYIKEAVKKSLTRLKTDYIDLYQLHGGTIEDNIDETIEAFEELKQEGVIRYYGISSIRPNVIKEYVKKSNIVSIMMQFSLFDRRPEEWLPLLEEHQISVVARGPVAKGLLTEKPLDQASESMKQNGYLSYSFEELTNARKAMEEVAPDLSMTEKSLQYLLAQPAVASVITGASKIEQLRENIQAANARRLTEEEIKALQSHTKQDIYKAHRS
What are the official names of this protein?
Uncharacterized oxidoreductase YqkF.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: SSEL_SALPA
Sequence: MNICVNSLYRLSTPQFHSLYSEEVSDETLALLIGEVENGNQNCIDLLCNLALRNDNLGHKVEKLLFDLFSGKRSGSPDIDKKINQACLVLHQIANNDITKNNTEWKKLHAPSRLLYMAGSATTDLSKKIEIAHKIMGDQFAQTDQEQVGVENLWCGARMLSSDELAAATQGLAQESPLLSVNYPIGLIHPTTKENILSTQLLEKIAQSGLSHNEVFLVNTGDHWLLCLFYKLAEKIKCLIFNTYYDLNENTKQEIIEAAKIAGISENEDIDFIETNLQNNVPNGCGLFCYHTIQLLSNAGQNDPATTLREFAENFLTLSVEEQTLFNTQTRRQIYEYSLQ
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity).
What are the official names of this protein?
Deubiquitinase SseL, Deubiquitinating enzyme, DUB, Deubiquitinating protease, Salmonella secreted effector L.
What is the protein family that this protein belongs to?
Belongs to the peptidase C79 family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cytoplasm. In phagocytic cells localizes to the Salmonella-containing vacuole (SCV). In epithelial cells localizes to the Salmonella-containing vacuole (SCV) and to the Salmonella-induced filaments (Sifs), which are tubular membrane extensions from the SCV that are formed at late stages of infection (By similarity).
Protein: FEN_SACS2
Sequence: MDLADLVKDVKRELSFSELKGKRVSIDGYNALYQFLAAIRQPDGTPLMDSQGRVTSHLSGLFYRTINILEEGVIPIYVFDGKPPEQKSEELERRRKAKEEAERKLERAKSEGKIEELRKYSQAILRLSNIMVEESKKLLRAMGIPIVQAPSEGEAEAAYLNKLGLSWAAASQDYDAILFGAKRLVRNLTITGKRKLPNKDVYVEIKPELIETEILLKKLGITREQLIDIGILIGTDYNPDGIRGIGPERALKIIKKYGKIEKAMEYGEISKKDINFNIDEIRGLFLNPQVVKPEEALDLNEPNGEDIINILVYEHNFSEERVKNGIERLTKAIKEAKGASRQTGLDRWF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).  DNA polymerase I, DNA ligase and the flap endonuclease may be constitutively associated with the PCNA heterotrimer forming a scanning complex able to couple DNA synthesis and Okazaki fragment maturation.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: CDAS_BACSU
Sequence: MKAMRYEQISENAFKGKIQVYLEQILGDASLILKTLHEKDQCLLCELDDLGHVFQDMQGIASSFYLQSYIEEFTPAFIELAKAIKALSEHKHGALIVIERADPVERFIQKGTSLHAEISSSLIESIFFPGNPLHDGALLVRENKLVSAANVLPLTTKEVDIHLGTRHRAALGMSGYTDALVLVVSEETGKMSFAKDGVLYPLISPRT
What is the function of this protein?
One of 3 paralogous diadenylate cyclases (DAC) in this bacteria, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP) (Probable).  Upon expression in E. coli leads to c-di-AMP synthesis (PubMed:23192352, PubMed:24939848).  Overexpression of the hyperactive mutant (L44F) in the absence of c-di-AMP phosphodiesterase GdpP leads to growth defects in log phase (long curly cell filaments) that disappear upon sporulation; spore formation is normal, showing sporulation is insensitive to the excess c-di-AMP (PubMed:23192352).  In B. subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess.
What are the official names of this protein?
Cyclic di-AMP synthase CdaS, c-di-AMP synthase, Diadenylate cyclase, DAC.
What is the protein family that this protein belongs to?
Belongs to the adenylate cyclase family. DacB/CdaS subfamily.
Protein: Y2598_MYCBO
Sequence: MRDFHCPNCGQRLAFENSACLSCGSALGFSLGRMALLVIADDADVQLCANLHLAQCNWLVPSDQLGGLCSSCVLTIERPSDTNTAGLAEFARAEGAKRRLIAELHELKLPIVGRDQDPDHGLAFRLLSSAHENVTTGHQNGVITLDLAEGDDVHREQLRVEMDEPYRTLLGHFRHEIGHYYFYRLIASSSDYLSRFNELFGDPDADYSQALDRHYRGGPPEGWQDSFVSSYATMHASEDWAETFAHYLHIRDALDTAAWCGLAPASATFDRPALGPSAFNTIIDKWLPLSWSLNMVNRSMGHDDLYPFVLPAAVLEKMRFIHTVVDEVAPDFEPAHSRRTV
What are the official names of this protein?
Uncharacterized protein Mb2598c.
Protein: INX12_CAEEL
Sequence: MNVIQNLLSAVSPQPDGDFVDKLNYCATTIGLVLASAFITGWSFVGSPIDCWFPAYYKGWWAEYALDYCYVQNTFFVPFSEDKAERSYNWEQLVADKQNTTSLKQTNQIGYYQWVPFILALQAMLFYFPVVIWRLFYGMAGQNVTSLCNTCTATEGNEESRKGTITTIAGYISQKRHRNLIVKQLSGFQNRANGSAVITSYLFMKALFLINVLFQFVLLKRMLGVDSYFWGAEVTSDLWSGNEWPETGNFPRVTMCEYEVRNLDNIHKHSVQCVLMINMFNEKIFVALWWWLCFLTVVTITNTIYWFWRASGTSVSKNFIRPYVEDIDPKVKNNRGKLQQFVSEFLSPDTVFILRLIELNNGKTPVVELIRDMWRRFNTAVPPPYSAPPLLVKDGAPLLKNFQDESEM
What is the function of this protein?
Structural component of the gap junctions (By similarity).  Plays a role in oocyte directional transit in the spermatheca during ovulation by facilitating the directional propagation of the calcium signal in the spermatheca (PubMed:23671426).  Plays a role in male tail tip morphogenesis (PubMed:21408209).
What are the official names of this protein?
Innexin-12, Protein opu-12.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: CYB_RUCSC
Sequence: MINIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDADKIPFYPYYTIKDILGILLLILFLMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVSSILILILMPLLHTSKQRSMMFRPFSQCLFWVLVADLLTLTWIGGQPVEYPFIIIGQLASILYFFIILVLMPITSTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURA2_BACAN
Sequence: MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGRVTYGQEEEMVVDPSNMVAMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLDVVSVGATINIMLAAVRAKGRTVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYMILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYPGFPTDLQQPFTTLLTKAHGTGVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLLQGAKVKASDLRAGAALVIAGLMADGITEVTGLEHIDRGYENIVDKLKGLGANIWREQMTKQEIEEMKNA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_XANCB
Sequence: MSDEILNGAAAPADAAAGPAFTIEKIYVKDVSFESPNAPAVFNDANQPELQLNLNQKVQRLNDNAFEVVLAVTLTCTAGGKTAYVAEVQQAGVFGLVGLEPQAIDVLLGTQCPNILFPYVRTLVSDLIQAGGFPPFYLQPINFEALYAETLRQRSQGETSLADSEPAGNA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIDA_MACFA
Sequence: MFSSYRLARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE
What is the function of this protein?
Acts as a ventralizing factor during embryogenesis.  Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization.  This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
What are the official names of this protein?
Axin interactor, dorsalization-associated protein, Axin interaction partner and dorsalization antagonist.
What is the protein family that this protein belongs to?
Belongs to the AIDA family.
Protein: PSBC_STIHE
Sequence: METLYNGTLSLGGKDQESTGFAWWSGNARLINLSGRLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLASLGYGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGVYHSLIGPETLEETFPFFGYTWKDKNKMTSILGFHLIILGFGAWLLVWKAMYFGGVYDTWAPGGGDTRIITNPTTNPAVIFGYLLKSPFGGDGWIVSVDNMEDIIGGHIWIGTLEIFGGIWHIFTQPWAWTRRAFVWSGEAYLSYSLGAIALMGFVACCMGWFNNTAYPSEFYGPTGPEASQSQAFTFLVRDQRLGANVASAQGPTGLGKYLMRSPTGEIIFGGETMRFWDFRGPWLEPLRGPNGLDLNKLKNDIQPWQERRAAEYMTHAPLGSLNSVGGVATEINSVNFVSPRSWLATSHFCLGFFFFVGHLWHAGRARAAAAGFEKGIDRLTEPVLSLKPLD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL31B_LACH4
Sequence: MKQGIHPDFQKVVFMDSATGAKFLAGSTLKPEETVDYEGETYPLVRVEVSSDSHPFYTGKQKFAQADGRIEKFNKKYGLKK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: GLYA_PSYCK
Sequence: MFKDISIKDFDPVLAEAMAAESVRQENHIELIASENYCSQAVMEAQGTDLTNKYAEGYPGKRYYGGCEHVDVVEQLAIDRAKELFGAEYVNVQPHSGSQANSAVFLALLEANDTVLGMSLDAGGHLTHGAHINFSGLNYNAVQYGLVEGTGLIDYDQVESLAKEHKPKMIIAGFSAYSQVVDWARFREIADEVGAYLLVDMAHVAGLIAGGVYPSPVPFADVVTTTTHKTLRGPRSGMILARDEVLAKKLNSAVFPGNQGGPLMHVIAAKAVCFKEALEENFKTYQQQVVKNAQAMAKVIQDRGYEIISGGTENHLMLISLVKQEMTGKEADKWLGDAHITVNKNAVPNDPKSPFVTSGIRIGTPAITTRGFNEAQAGDLAGWICDVLDSRGDEAVTAEVRGKVEAICKELPVYAKNQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRGB_STAA8
Sequence: MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  Increases tolerance to penicillin possibly by inhibiting the formation of the CidAB holin-like complexes within the membrane, thus reducing penicillin-induced lethality.  Possibly plays a role in programmed cell death (PCD), triggering PCD in response to penicillin, and possibly other antibiotics, and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H2B_ASPNC
Sequence: MPPKAAEKKPSTGGKAPAGGKAPAEKKEAGKKTAAAASGDKKKRGKTRKETYSSYIYKVLKQVHPDTGISTRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HIS1_LEPBA
Sequence: MLTLALPKGRLAEETALLLLSKGWLKNLPSEGSKELTYVSEDKRIRLLFVRSQDVCTYVEEAAADVGIVGWDIIREGGFDLIAPVDLKLGACRLSLASFPDFDLFAKRSKVRVATKYPNLTREYFFSKGISCEIIKLYGSIELAPIVGLSDCIVDLVSTGGTLKANGLKEFESILFSTARLVSNRSSFYHKHAELRSLIESLEN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_BREDI
Sequence: AKTENKTVTVRQTASPIXXXK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TY01_PHYBU
Sequence: EPPPWVPV
What are the official names of this protein?
Tryptophyllin-like peptide PbT-1.
What are the subcellular locations of this protein?
Secreted.
Protein: KLRE1_MOUSE
Sequence: MDEAPVTRSTLNVNSQQKSKAKNKIKNTLNSNELSSIEQRKKYQKHLKKHKNTAEDISGKGNCSPPWRLLSSVLGAMCLLLMAVAMVMTTFTTKSSSERSSSTIQQEGLHHPCPENWVWFRCSCYFFSKEELIWRDSQRACLSLNSSLIRMNKEEMNFFSLKSFFWVGVYYNETRRQWLWEDHSVLPSGLFSKLEANMKNFCASYKSKEAYMEENCANKLTYICKK
What is the function of this protein?
Lectin-like receptor for natural killer (NK) cells (PubMed:14707119, PubMed:15069013, PubMed:18713988).  Can either inhibit or activate NK cell cytotoxic activity, depending on its binding partner (PubMed:14707119, PubMed:15069013, PubMed:18713988).  Heterodimer formation with KLRI1 mediates NK cell inhibition whereas heterodimer formation with KLRI2 mediates NK cell activation (PubMed:18713988).  Plays a role in allogeneic recognition by the immune system (PubMed:14707119, PubMed:15069013).
What are the official names of this protein?
Killer cell lectin-like receptor subfamily E member 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: CURG_STRCN
Sequence: MHHALIVARIARSPAQDIAGVFAASDPGELRHLVGVTQRSLFQFGDVYMHFIEAGAGPGPRIAKVTGHPEFVDISRKLEAYVSPYDPQTWRSPRDAMGRCFYHWERD
What are the official names of this protein?
Polyketide synthase CurG.
Protein: ATPL_ECODH
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROC_STAAC
Sequence: MRYLTSGESHGPQLTVIVEGVPANIEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIYSRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLDGKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLKQQIIERRQLNIEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: GAGY_DROME
Sequence: MSWAHNYRKVKVEYESEDSWEEEQVGQALGRPLDSATVDITMDPNQIQALIDNAVRQALSQQQSQFQTQLNSLAARVQSLQVEAPQIKIYEKVSVNPDVRCDIPLDIIKSVPEFSGTQDEYVAWRQSAIYAYELFKPYNGSSAHYQAVAILRNKIRGAAGALLVSHNTVLNFDAILARLDCTYSDKTSLRLLRQGLEMVRQGDLPLMQYYDEVEKKLTLVTNKIVMTHEQEGADLLNAEVRADALHAFISGLKKALRAVVFPAQPKDLPSALALAREAEASIERSMFANSYAKAVEERAHSGANGKSRFQGKPNKEEQGQDRNPHFTKRPKNNGQTNKDTQAQAPQPMEVDSSSRFRQRTEHYQNHPNESNAFKRRNSSERSTGPRRQRLNNVVQEAPKQKDPKEEYEKTAKAAVEEIDSENEYAPSDDSLNFLGGAPGCRSLNDGWLGEP
What are the official names of this protein?
Retrovirus-related Gag polyprotein from transposon gypsy.
What are the subcellular locations of this protein?
Virion.
Protein: DNLJ_YERP3
Sequence: MESIIQQINQLRTSLRHHEHQYHVLDAPEIPDAEYDRMMQQLRDLEAQHPELVTNDSPTQRVGAAPLDAFEQVEHEVPMLSLDNVFDEESYLAFDKRVHDRLKTAEPLTFCCELKLDGLAVSLLYENGELVRAATRGDGTTGENITANVRTIRAIPLRLHGDNVPRRVEVRGEVFMPQAGFEQLNEEARRKGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGLLDGGELPRSHIQCLMQFKAWGLPVSERVKLCTGSDQVIAFYRQIEQDRAGLGFDIDGVVIKVDDLVLQEQLGFVARAPRWATAFKFPAQEQITQVREVEFQVGRTGAITPVARLEPVQVAGVIVSNATLHNADEIERLGLRIGDTVIVRRAGDVIPQVVGVVMEQRPDDTKEITFPSQCPVCGSDIERVEGEAVARCTGGLFCAAQRKEALKHFVSRRALDVDGMGDKIIEQLVEKQYVENPADLFQLTAGKLTGLDRMGPKSAQNLIAALEKAKQTTFARFLYALGIREVGEATAANLAAHFRTLDNLRAADIETLKSVPDVGEVVAKHVMNFLSEEHNQKVIEELEKVVSWPEPQQIVVEEIDSPFAGKTVVLTGSLTILSRDEAKDRLTALGAKVSGSVSKKTHLVIAGEAAGSKLAKAQELGIKVIDEAEMIRLLGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.