PharMolix/UniProtQA huggingface dataset:
Protein: TRMFO_STRT2
Sequence: MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREGYAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFYDAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQSKSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTHAESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERSLKDLQTFIDA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3117_METAC
Sequence: MIDLNKISKVVVVFIVLLTFLVLMMQSQEVKVAGLLIQFENETTEPEVTAILENYDIPVNYTIDYNSNIGRGVYYVKVDEDKINELRKNENLISEIELKKGNYNIIILSEEFVPDENFLTILEKNNLQLKKVVVCYIHFGDGPADWVVGKNCILERDAIRIKNELETNEKVLIVGLDDIEG
What are the official names of this protein?
UPF0228 protein MA_3117.
What is the protein family that this protein belongs to?
Belongs to the UPF0228 family.
Protein: RIP3_MAIZE
Sequence: MAEITLEPSDLMAQTNKRIVPKFTEIFPVEDANYPYSAFIASVRKDVIKHCTDHKGIFQPVLPPEKKVPELWLYTELKTRTSSITLAIRMDNLYLVGFRTPGGVWWEFGKDGDTHLLGDNPRWLGFGGRYQDLIGNKGLETVTMGRAEMTRAVNDLAKKKKMATLEEEEVQMQMQMPEAADLAAAAAADPQADTKSKLVKLVVMVCEGLRFNTVSRTVDAGFNSQHGVTLTVTQGKQVQKWDRISKAAFEWADHPTAVIPDMQKLGIKDKNEAARIVALVKNQTTACATAASADNDDDEA
What is the function of this protein?
Possesses features of some constitutive defense agent.  The coordinate Opaque-2-controlled synthesis of this protein and the major seed storage proteins (zeins) may provide the germinating seedling with both nutritional benefits and protection against pathogen invasion of the surrounding endosperm.
What are the official names of this protein?
Ribosome-inactivating protein 3, B-32 protein, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_STRM5
Sequence: MTRTALVTTALPYANGPLHLGHLVGYIQADIWVRARRMSGGKAWFVCADDTHGTPIMLAAEKAGVTPETFIANIQASHERDFAAFGVAFDHYDSTNSAANKALTEQFYLKLEAAGHISRRSVAQFYDPAKGMFLPDRYVKGICPNCGSADQYGDNCEVCGATYAPTDLKEPRSVVSGATPEMRDSEHFFFEVGHFDGFLRDWLAGDVALPGVKAKLGEWLNAEGGLRAWDISRDAPYFGFEIPGQPGKYFYVWLDAPIGYLSSFQTLCSRIGEDFEAHLRAGTSTELHHFLGKDIVNFHGLFWPAVLHGTGHRAPTRLHVNGYLTVDGAKMSKSRGTFVMARTFLDAGLEPEALRYYFAAKSGGGVDDLDLNLGDFIARVNADLVGKFVNLASRCAGFISKRFDGLLAAQLPDAAQYQRFVDGLAPIREAYERNDPAAAIRLTMTLADEANRYIDDVKPWVIAKQEGADAQLQAVCSQGLNLFRVLVTALKPVLPATAAQAEAFLAAPVNDWTELAQPLLGHRITDYTPLFTRIDPKKIDAMIDASKDTLQTTAAAAPTAKNEAAKPAAPAAAKTEANNADAPATIGIDDFAKLDLRIGKVLVCEFVEGSDKLLRFELDAGELGKRQIFSGIRGSYGEPEKLVGRSVVFIANLAPRKMRFGLSEGMILSAGFDGGALALLDADSGAQPGMPVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNG2_RAT
Sequence: MARLPGHPEVPGAEPGSAVRGGRGGRGARARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDELLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARATPPARGPQTSPGRALGSGRLERGRRRLRDVVENPHSGLAGKLFAYVSVAFVAVTAVGLCLSTMPDVRAEEERGECSTKCRNLFVLETVCVAWFSFEFLLRSLQAESKCAFLRTPLAIIDILAILPFYVSLLAGLAAGPTGSKMLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTVRRCAREFGLLLLFLCVAMALFAPLVHLAERELGAHRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPVLREDSTRDDSTRSASATEDSSQDPETAGAAGSLPGPVGP
What is the function of this protein?
Potassium channel subunit.  Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily G member 2, Cardiac potassium channel subunit, Voltage-gated potassium channel subunit Kv6.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.2/KCNG2 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HM16_CAEEL
Sequence: MILKFGIERILSSPYPCPSPTISTPATSPSSISPTFASPNGTPNIASSMYPAWVFSTRYSDRPSAGPRHRKSRKRESTGSSGSSEEEKRPRTAFTGDQLDRLKTEFRESRYLTEKRRQELAHELGLNESQIKIWFQNKRAKLKKSTSSVPRDRCSSVTPNPHNHPSIHGGYQLMAQLAKVQARAYMP
What is the function of this protein?
Transcriptional regulator which binds to DNA to regulate gene expression and promote seam cell development and differentiation during embryogenesis (PubMed:15659483, PubMed:19607822).  Plays a role in maintaining the boundaries between the lateral rows of seam cells and the ventral and dorsal row of epidermal cells during embryonic development (PubMed:15659483).  Negatively regulates the expression of the fusion effector protein eff-1 to prevent seam cell fusion with the dorsal and ventral epidermal cells during embryonic elongation (PubMed:15659483).  Positively regulates seam cell self-renewal and expansion during the L2 larval stage to promote seam cell development (PubMed:19607822).  This role does not seem to be via regulation of eff-1 expression (PubMed:19607822).  Specifically, it is required for the asymmetric division of the V5. p seam cell during the L2 larval stage, and in turn the asymmetric nuclear distribution of pop-1 in V5. p daughter cells (PubMed:19607822).
What are the official names of this protein?
Homeobox protein engrailed-like ceh-16.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HPF_STAAM
Sequence: MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
What is the function of this protein?
Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
What are the official names of this protein?
Ribosome hibernation promotion factor, HPF.
What is the protein family that this protein belongs to?
Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PR23A_HUMAN
Sequence: MGSRPRSPSAFPAPWWGQQPGGPGPAKRLRLEEPAGPEPRVAPSLEDPAGTPAVGALTSIVVLAAGCALRVPLDDVDLVLELPPTSILRVSLDGHTLILIPEVLLSSVDERSGAQDDSSAGLEVDVFLGALREDVVVEQEVFCASVPEIAAQEEAYEEDADPEFPELQMDSAAGSAAGLYSSARSMFSPYREGPIPEPCALAPNPSSEGHSPGPFFDPEFRLLEPVPSSPLQPLPPSPRVGSPGPHAHPPLPKRPPCKARRRLFQE
What are the official names of this protein?
Proline-rich protein 23A.
What is the protein family that this protein belongs to?
Belongs to the PRR23 family.
Protein: AMPN_MOUSE
Sequence: MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSATAPTLPGSTSATTATTTPAVDESKPWNQYRLPKTLIPDSYRVILRPYLTPNNQGLYIFQGNSTVRFTCNQTTDVIIIHSKKLNYTLKGNHRVVLRTLDGTPAPNIDKTELVERTEYLVVHLQGSLVEGRQYEMDSQFQGELADDLAGFYRSEYMEGDVKKVVATTQMQAADARKSFPCFDEPAMKAMFNITLIYPNNLIALSNMLPKESKPYPEDPSCTMTEFHSTPKMSTYLLAYIVSEFKNISSVSANGVQIGIWARPSAIDEGQGDYALNVTGPILNFFAQHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYRESSLVFDSQSSSISNKERVVTVIAHELAHQWFGNLVTVAWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSSPADEIKTPDQIMELFDSITYSKGASVIRMLSSFLTEDLFKKGLSSYLHTYQYSNTVYLDLWEHLQKAVNQQTAVQPPATVRTIMDRWILQMGFPVITVNTNTGEISQKHFLLDSKSNVTRPSEFNYIWIAPIPFLKSGQEDHYWLDVEKNQSAKFQTSSNEWILLNINVTGYYLVNYDENNWKKLQNQLQTDLSVIPVINRAQIIHDSFNLASAKMIPITLALDNTLFLVKEAEYMPWQAALSSLNYFTLMFDRSEVYGPMKRYLKKQVTPLFFYFQNRTNNWVNRPPTLMEQYNEINAISTACSSGLKECRDLVVELYSQWMKNPNNNTIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRNATLVNEADKLRSALACSKDVWILNRYLSYTLNPDYIRKQDTTSTIISIASNVAGHPLVWDFVRSNWKKLFENYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKADNSATGFGTGTRALEQALEKTRANIDWVKENKDAVFKWFTENSS
What is the function of this protein?
Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases.  Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines (By similarity).  May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells (PubMed:8691132).  May have a role in angiogenesis and promote cholesterol crystallization (By similarity).  May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity (PubMed:22677001).
What are the official names of this protein?
Aminopeptidase N, AP-N, mAPN, Alanyl aminopeptidase, Aminopeptidase M, AP-M, Membrane protein p161, Microsomal aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Also found as a soluble form.
Protein: RIMS4_MOUSE
Sequence: MERSQSRLSLSASFEALAIYFPCMNSFDDEDAADSRRLKGAIQRSTETGLAVEMPSRTLRQASHESIEDSMNSYGSEGNLNYGGVCLASDAQFSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGVCIAKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSSMVDPATGPLLRQASQLSLESTVGPCGERS
What is the function of this protein?
Regulates synaptic membrane exocytosis.
What are the official names of this protein?
Regulating synaptic membrane exocytosis protein 4, RIM4 gamma, Rab3-interacting molecule 4, RIM 4.
What are the subcellular locations of this protein?
Synapse.
Protein: RBBP4_PONAB
Sequence: MADKEAAFDDAVEERVINEEHKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS
What is the function of this protein?
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.  Component of several complexes which regulate chromatin metabolism.  These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
What are the official names of this protein?
Histone-binding protein RBBP4, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Note=Localizes to chromatin as part of the PRC2 complex.
Protein: ML_THOGV
Sequence: MASNLPVRSFSEVCCAEARAAIIQMENNPDETVCNRIWKIHRDLQSSDLTTTVQVMMVYRFISKRVPEGCFAILSGVNTGMYNPRELKRSYVQSLSSGTSCEFLRSLDKLAKNLLAVHVCSDVKMSLNKRQVIDFISGEEDPTLHTAEHLTSLALDDSPSAVVYSGWQQEAIKLHNTIRKIATMRPADCKAGKFYSDILSACDQTKELLDAFDQGKLAYDRDVVLIGWMDEIIKIFSKPDYLEAKGVSYQVLKNVSNKVALLRESIWWVTELDGREYLFFDESWYLHGMSAFSDGVPGYEDFIY
What is the function of this protein?
Blocks host IRF3 and IRF7, thereby inhibiting IFN-beta expression and activation of host antiviral state.
What are the official names of this protein?
Protein ML, ML.
Protein: EF1B_PYRAR
Sequence: MSAEVALVYRVLPDSVEVNIDKLKTDIINKLSPKYKVDKVEVEEIGFGIKALRFYIRMPESEEYSSDEVEELLRSVEGVGGYELEYFSRLSF
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: HAS1_DEBHA
Sequence: MAVSSKSKTGRSPKPAKVQPSKKVESRKREHEEESSDSSESDNEKLVEELDDDFDEVAELLGDDIKDPEAKKDKKKEKKIQEEERTRELTKPTAESNHDDIVTDNFEEAGLSEPTLKAIKDMGFSKMTQVQAKTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIEMLYSLRFKPRNGTGVVVVSPTRELALQIFGVARELMAHHSQTFGIVIGGANRRQEAEKLMKGVNLLIATPGRLLDHLQNTQGFVFKNVKALVIDEADRILEIGFEEEMKQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLYINVASESEASTVAGLEQGYVVCESDKRFLLLFSFLKRNVKKKIIVFLSSCNCVKYFGELLNYIDLPVLDLHGKQKQQKRTNTFFEFCNATQGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTAGKGKSLMFLTPSELGFLRYLKAANVPLNEYEFPTNKIANVQSQLTKLIKGNYWLHQSAKDGYRSYLQAYASHHLKTVYQIDKLDLVKVAKSFGFDVPPKVNITIGASGKSIEKKHKKQKRA
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase HAS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL18_SHEHH
Sequence: MDKKTSRLRRALRARKKIQELGVNRLVVHRTPRHTYAQVISPENVVLAAASTAEKAVTEQLKYTGNVDAAKVVGKTVAERAIEKGVAVVAFDRSGFKYHGRVAALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: KCY_AERPE
Sequence: MISGPPGSGKSTYAKRLAEDLGLSYYSTGTIFRSIARERGLSLAEMSRLAEEDPRIDLEIDRRTLDVASRGGVVIDSHLAAWLLRDKAQYLVLVKAPVWVRVRRIARRDGVPLRRALAETVEREWSQRLRFKRYYGIDVSDTTIFHLTVDTSMYSVEDTYRLILEGARRRGL
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_BACC4
Sequence: MNIHEYQGKAVLRSYGVSVPNGKVAFTVEEAVEAAKELGTDVCVVKAQIHAGGRGKAGGVKVAKNLDEVRTYAESILGTTLVTHQTGPEGKEVKRLLIEEGCDIKKEYYVGLVLDRATSQVVLMASEEGGTEIEEVAEKTPEKIFKEYIDPAVGLQGFQARRIAFNINIPKELVGQAVKFMMGLYRAFIEKDCSIAEINPLVTTGEGKVMALDAKLNFDSNALYRHKDILELRDLDEEDSKEIEASKYDLNYIPLDGNIGCMVNGAGLAMATMDIIKHYHGDPANFLDVGGGATAEKVTEAFKIILSDKNVKGIFVNIFGGIMKCDVIAEGVIEATKQVGLELPLVVRLEGTNVELGKKILNESGLNIVAAESMADGAQKIVSLVG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: Y702_ENCCU
Sequence: MRSISVGLDREESGSDGLCLGLVVLATLAAGFVAGSDVLRCRGFGPATGDVCLWVGAGFWRCPLPGGGADGQGPGFWDAALREARMFCRSCVGLRMIGWRR
What are the official names of this protein?
Uncharacterized protein ECU07_0020.
Protein: GLRX1_CHICK
Sequence: MVDSFVQSKLRDNKVTLFVKGSCPYCKNAIVLLKEFNFLPGCLEVVDITGMDDIQDYFQKTTGQRTVPRVFIGTKCIGGFSDLQKMEQQLPMMLRQIGALV
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins.
What are the official names of this protein?
Glutaredoxin-1, Thioltransferase-1, TTase-1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_METHJ
Sequence: MIKVAINGYGTIGKRVADAVSAQKDMEIIGVSKTKPSAEALIAVQRGYPIYIADMSKKDAFAKAGIPVAGSVEDMLKKADIVVDGTPGGVGESNKALYEKAGVKAIWQGGEDHEVAGFSFNAHANYKDAIGRQFVRVVSCNTTGLCRVIKAVDDAFGVVKVRAVMVRRGADPHVVKKGPIDAVVLDPPTIPSHHGPDVNTVLPHIDIVTMAMIVPTTQMHMHAITIELKKEVSRDDVLAVMRSHNRIGLVQPKTAIKSTAELKEYVMDMGRPRSDLWENGIFEASVNMVGKELFFFQAIHQEADVVIENVDAIRAMMGEVRDPETSIRMTNEAMQFTAL
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S22A2_RABIT
Sequence: MPTVDDILEQVGHFHFFQKQTFFLLALISAAFTPIYVGIVFLGFTPDHRCRSPGVAELSQRCGWSPGEELNYTVPGLGAADGAFARQCMRYEVDWNQSSPGCVDPLASLAPNRSHLPLGPCQHGWVYDTPGSSIVTEFNLVCARSWMLDLFQSAVNIGFFIGSVGIGYLADRFGRKLCLLVTILINAAAGVLMAVSPNYTWMLIFRLIQGLVSKAGWLIGYILITEFVGLNYRRTVGILYQVAFTVGLLVLAGVAYALPRWRWLQLTVTLPYFCFLLYYWCIPESPRWLISQNKNAKAMRIMEHIAKKNGKSLPVSLQSLRAAEDVGEKLNPSFLDLVRTPQIRKHTCILMYNWFTSSVLYQGLIMHLGLAGGDIYLDFFYSALVEFPAAFLIIATIDRVGRRYPWAVSNMVAGAACLASVFVPDDLQGLRITVACLGRMGITMAYEMVCLVNAELYPTFIRNLGVLVCSSLCDVGGIVTPFLVYRLTAIWLQLPLVVFAVVGLVAGGLVLMLPETKGRTLPETIEEAENLQRPRKNREKVIYVHVRKADGPLT
What is the function of this protein?
Electrogenic voltage-dependent transporter that mediates the transport of a variety of organic cations such as endogenous bioactive amines, cationic drugs and xenobiotics.  Functions as a Na(+)-independent, bidirectional uniporter.  Cation cellular uptake or release is driven by the electrochemical potential, i. e.  membrane potential and concentration gradient (By similarity).  However, may also engage electroneutral cation exchange when saturating concentrations of cation substrates are reached (By similarity).  Predominantly expressed at the basolateral membrane of hepatocytes and proximal tubules and involved in the uptake and disposition of cationic compounds by hepatic and renal clearance from the blood flow.  Implicated in monoamine neurotransmitters uptake such as histamine, dopamine, adrenaline/epinephrine, noradrenaline/norepinephrine, serotonin and tyramine, thereby supporting a physiological role in the central nervous system by regulating interstitial concentrations of neurotransmitters.  Also capable of transporting dopaminergic neuromodulators cyclo(his-pro), salsolinol and N-methyl-salsolinol, thereby involved in the maintenance of dopaminergic cell integrity in the central nervous system.  Mediates the bidirectional transport of acetylcholine (ACh) at the apical membrane of ciliated cell in airway epithelium, thereby playing a role in luminal release of ACh from bronchial epithelium.  Also transports guanidine and endogenous monoamines such as vitamin B1/thiamine, creatinine and N-1-methylnicotinamide (NMN).  Mediates the uptake and efflux of quaternary ammonium compound choline.  Mediates the bidirectional transport of polyamine agmatine and the uptake of polyamines putrescine and spermidine.  Able to transport non-amine endogenous compounds such as prostaglandin E2 (PGE2) and prostaglandin F2-alpha (PGF2-alpha).  Also involved in the uptake of xenobiotic 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP).  May contribute to regulate the transport of organic compounds in testis across the blood-testis-barrier (By similarity).
What are the official names of this protein?
Solute carrier family 22 member 2, Organic cation transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1459_GLUOX
Sequence: MELGLTGKLLVAAPALAETFFERTVIYLCAHSEQDGAMGLIVNRRLSQPGLDDLFAQLGIEPSPPERRIGVCMGGPVEHARGFVLHSADWAGEGSLDVDGHTTLTASLDILREIAAGHGPRQAVMALGHAAWAPGQLEEEILRDSSWFIAPATDEIVFGTDHAKKWRQALVAIDFDPLLLSSSVGEA
What are the official names of this protein?
UPF0301 protein GOX1459.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: Y070_NPVAC
Sequence: MDSLANLCLKTLPYKFEPPKFLRTKYCDACRYRFLPKFSDEKFCGQCICNICNNPKNIDCPSSYISKIKPKKENKEIYITSNKFNKTCKNECNQQSNRRCLISYFTNESCKELNCCWFNKNCYMCLEYKKNLYNVNLYTIDGHCPSFKAVCFSCIKRIKTCQVCNQPLLKMYKEKQEERLKMQSLYATLADVDLKILDIYDVDNYSRKMILCAQCHIFARCFCTNTMQCFCPRQGYKCECICRRSKYFKNNVLCVKSKAACFNKMKIKRVPKWKHSVDYTFKSIYKLINV
What are the official names of this protein?
Uncharacterized 34.4 kDa protein in LEF3-IAP2 intergenic region.
Protein: APOA1_PAPHA
Sequence: MKATVLTLAVLFLTGSQARHFWQQDEPPQTPWDRVKDLVTVYVEALKDSGKDYVSQFEGSALGKQLNLKLLDNWDSVTSTVSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELHEGTRQKLHELHEKLSPLGEEVRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKASEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLSTQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_LACDB
Sequence: MNGKQLVAEALQAVLPDWSLDDIDVKIERPKDEKLGDYAFPTFTLAKTMRKAPNLIAVELAEKIDQGSFEKVEAVGPYINFFLDKSQTGAAILQEILADPENYGARDLGHGRNVLTEYSSPNIAKPMGMGHLRSTMIGEAIARILAKEGFKPIRIDYLGDWGTQFGKMMAAYKMWGNDADIEKDPINTLLSYYVRINREAEEHPEYDEDGREWFSKLEHGDEEAKRLWSWFREVSLERFKKVYDMLDVHFDSFTGEAFSAQMMDKPIQILREKGLLVKSQGAEIVDLEKYNLPPLMVIKSNGTSTYITRDLATAMYRKKTYGFYKSIYVVGQEQEVYFQQLRACLKEMGFDWADDIVHISFGLMSINGQKMSTRKGNVVNLEDVLNESVDLARKQISEKNAGLKNADEVAKQVGIGAVVFHDLKNYRRNPIDFNLEEVVKFEGETGPYVQYARARGESLLRKSGITDFSDADLTKIGAEEWDLVSFMARYADTIQKAMETYDPSAIAKYALELAKRFNKYYAHTRILVDDVDEDVKKARLAVVQAVSHVIKSALDLLDVKAPDEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTM2_HUMAN
Sequence: MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276).
What are the official names of this protein?
Glutathione S-transferase Mu 2, GST class-mu 2, GSTM2-2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.