PharMolix/UniProtQA huggingface dataset:
Protein: MACD1_BOVIN
Sequence: MFLQSRVSRLLAQLRAAGQLLGAPRPWPGPSPGATRTRSSACGPPASLSAHHPRARTSAGVGAWGAAAVGRRAGVRTWAPLAMAAKVDLSTSTDWKEAKSFLKGLSDKQREEHYFCRDFVRLKKIPTWKETAKGVTVKVEEPKYKKDKQLNEKISLFRGDITKLEVDAIVNAANSSLLGGGGVDGCIHRAAGPLLTDECRTLQNCETGKAKITCGYRLPAKYVIHTVGPIAHGEPSASQAAELRSCYLSSLDLLLEHRLRSAAFPCISTGVFGYPNEAAAEVVLTALREWLEQHKDKVDRLIICVFLEKDENIYRERLPHYFPVA
What is the function of this protein?
Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety.  Inactive towards proteins bearing poly-ADP-ribose.  Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins.  Plays a role in estrogen signaling.  Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen.  May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation.  Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction.  Could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells.  Enhances ESR1-mediated transcription activity.
What are the official names of this protein?
ADP-ribose glycohydrolase MACROD1, MACRO domain-containing protein 1, O-acetyl-ADP-ribose deacetylase MACROD1, Protein LRP16, [Protein ADP-ribosylaspartate] hydrolase MACROD1, [Protein ADP-ribosylglutamate] hydrolase MACROD1.
What are the subcellular locations of this protein?
Nucleus. Note=Recruited to DNA lesions, probably via mono-APD-ribosylated proteins.
Protein: RRP36_LACTC
Sequence: MSYYFKNLKPGYESDEELEDDEILKTLSKRYADEDESASDDELSSLSFDALRRAERQLEEESRKEKAGSQNESKPALKNAKRSKEKELELADSFKAKSYTEESFGENSDSSSENEGLFEEEEVVRGNKNSKADHGKNRKKSHAPSEQSSKKKVSRIRKIPGLETPKSMNENLYQDIRFDKSLGKAEDYESIRKRYQFLDEYRQKEISELSRLLSDRKFVNKISERERDEMQEKLTSMRSKLQTLKNRDLDRKILKDYETEINKGNKTKYHLKESEKRKVIQKYKFDHMKAKQREKVMDRKRKKRLGKEFKQFSFHNR
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SLYD_YERPE
Sequence: MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDVRVNADEGYGSYDENLVQRVPKDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVDGNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHHEHGDGCCGGHGHDDHEHEHEHGKGGCGKSGGCGCH
What is the function of this protein?
Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step.  This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity (By similarity).
What are the official names of this protein?
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD, PPIase, Metallochaperone SlyD.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_CHLL3
Sequence: MRRKIVVGNWKMNKTVAESTALATAVIAALGDGCSACEAGIAPTYPALDAVGRALEGSGIALVAQNCHYEDDGAYTGEVSTGMLKAVGCSYVIIGHSERRQYFGETDETVNLRIKKVLASGMKVILCVGETLAEREEGVTGTVVSRQVTEGLKGVADITDLVIAYEPVWAIGTGKTASSDQAQEVHRLIRDTVKGMYGAEVSEAVRIQYGGSVKASNAEELFAMPDIDGGLIGGASLNAADFAAIVKAGC
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A2_OSCTI
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETAKFYVTIIDAPGHRDFIKNMITGTSQADCAVLVVACGTGEFEAGISKNGQTREHALLAQTLGVKQMIVACNKMDSTEPPFSEKRFEEIITEVKSFIKKIGYNPATIPFVPISGFNGDNMLEPSANMSWYKGWSVERKEGNASGKTLLEALDCIIPPQRPTDRPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPQNVTTEVKSVEMHHESLPEAQPGDNVGFNVKNVSVKDIRRGSVCSDSKNDPAKESKSFTAQVIVMNHPGQIGAGYTPVLDCHTAHIACKFAELKEKVDRRTGKKVEDPPKFLKSGDAGIVELIPTKPLCVEAFTDYAPLGRFAVRDMRQTVAVGVIKGVTKDDGSGGKVTKSAAKKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha 2, EF-1-alpha-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTSP_BOMMO
Sequence: MRWCLFALWVFGVATVVTAAEEPHHDAAPQTDNEVDLTEDDKRAWSSLHSGWAKRAWQDMSSAWGKRAWQDLNSAWGKRGWQDLNSAWGKRAWQDLNSAWGKRGWQDLNSAWGKRDDDEAMEKKSWQDLNSVWGKRAWQDLNSAWGKRAWQDLNSAWGKRGWNDISSVWGKRAWQDLNSAWGKRAWQDMSSAWGKRAPEKWAAFHGSWGKRSSIEPDYEEIDAVEQLVPYQQAPNEEHIDAPEKKAWSALHGTWGKRPVKPMFNNEHSATTNEA
What is the function of this protein?
Inhibits ecdysteroid biosynthesis in the prothoracic gland of fifth instar larvae, with maximum inhibition during the spinning stage.  When administered to day 8 fifth instar larvae it produces a significant delay in the commencement spinning behavior.
What are the official names of this protein?
Prothoracicostatic peptide, Bom-PTSP.
What are the subcellular locations of this protein?
Secreted.
Protein: ABAH3_ARATH
Sequence: MDFSGLFLTLSAAALFLCLLRFIAGVRRSSSTKLPLPPGTMGYPYVGETFQLYSQDPNVFFAAKQRRYGSVFKTHVLGCPCVMISSPEAAKFVLVTKSHLFKPTFPASKERMLGKQAIFFHQGDYHSKLRKLVLRAFMPDAIRNMVPHIESIAQESLNSWDGTQLNTYQEMKTYTFNVALISILGKDEVYYREDLKRCYYILEKGYNSMPINLPGTLFHKAMKARKELAQILANILSKRRQNPSSHTDLLGSFMEDKAGLTDEQIADNIIGVIFAARDTTASVLTWILKYLADNPTVLEAVTEEQMAIRKDKKEGESLTWEDTKKMPLTYRVIQETLRAATILSFTFREAVEDVEYEGYLIPKGWKVLPLFRNIHHNADIFSDPGKFDPSRFEVAPKPNTFMPFGSGIHSCPGNELAKLEISVLIHHLTTKYRWSIVGPSDGIQYGPFALPQNGLPIALERKP
What is the function of this protein?
Involved in the oxidative degradation of abscisic acid, but not in the isomerization of the produced 8'-hydroxyabscisic acid (8'-OH-ABA) to (-)-phaseic acid (PA).  Involved in the control of postgermination growth.
What are the official names of this protein?
Abscisic acid 8'-hydroxylase 3, ABA 8'-hydroxylase 3, Cytochrome P450 707A3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GIA6_GIAIN
Sequence: MVTTVQDLAEQLRQAVESSNEQMIAGLASAYSGKEREKVLRAYLSATGTTAADAIRKALKNGPTENLLAYLWDKPGDVRAKLIRNALSGKNDEAALIDLVIHCSSEDWYNTCTEYTTDYKRVLNDDLLSDIGTKEQWTKVFKHWILHKRSDRFDIDGDEKRLVTAIGKKDYDTIAEMLGTTSVSEYANIVRRAEVTLGKTIDQALSAVWSKQDLAVLLAAHYELLHPARLAFHLLKQALDGKKPDEARIIRITALTFDTCLAVKYAASEAGYDIGSAFAKALDKRLAPLIKILWRVM
What is the function of this protein?
Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst.  They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk (By similarity).
What are the official names of this protein?
Giardin subunit alpha-6.
What is the protein family that this protein belongs to?
Belongs to the annexin family. Giardin subunit alpha subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DC2L1_CHLRE
Sequence: MAAPAMLPGQAVKTPGSIWAKAIEHANEERKKPGADGRGDAFCYFVGSRAAGKSTLLNRFLYPTRAEVPKPSEGIEYTYARKPAAFDHEKKDLAHIWEVGGSQEFAEEIVNSDQLFLTAKQVTTAVVVIVVDLSDPAGVLPTLLYWVEQVKKKLGSTYEKFEKKGLQLPEQLRQRAKSKLYSANEDKDTVYHSGISLVIAATKYDAFKNQDPEVKKVMSRVLRYIAHAHGAFLCYLSGLHGASEGSGAEDAALLDNFTRLMNHLIFTGLEKKPVLKMQPQIDHTGPIMVPAGFDTFKSVGRPRSQGEGTVAGGLAEWRELFEKMFPGVREKEAKMSAKGAKFVIPEQYKEEEVDAVRQRKVTDLENFRKEQAAAVEAAKKKALMAKAQQAEAAAKKKAGAPAAGAKAPAKASPNGTPPRRPSNAGNQ
What is the function of this protein?
Functions as a motor for intraflagellar retrograde transport.  Functions in flagellar biogenesis.
What are the official names of this protein?
Cytoplasmic dynein 2 light intermediate chain 1, Dynein 1b light intermediate chain.
What is the protein family that this protein belongs to?
Belongs to the dynein light intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum basal body. Cell projection, cilium, flagellum membrane; Peripheral membrane protein. Cytoplasm.
Protein: SUSD4_HUMAN
Sequence: MYHGMNPSNGDGFLEQQQQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGFDDLQVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQEDCRIPQIEDAEIHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWNNLPICQGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCLALEVCPLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTTWKIVAFTATSVLLVLLLVILARMFQTKFKAHFPPRGPPRSSSSDPDFVVVDGVPVMLPSYDEAVSGGLSALGPGYMASVGQGCPLPVDDQSPPAYPGSGDTDTGPGESETCDSVSGSSELLQSLYSPPRCQESTHPASDNPDIIASTAEEVASTSPGIDIADEIPLMEEDP
What is the function of this protein?
Acts as complement inhibitor by disrupting the formation of the classical C3 convertase.  Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.
What are the official names of this protein?
Sushi domain-containing protein 4.
What are the subcellular locations of this protein?
[Isoform 1]: Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
Protein: ZN826_HUMAN
Sequence: MRRFILERNPTNVKNMAKLSPIPHTLLGIRKFMLERNHTSVINVAQPLFYPQPLVNMRRFILERNSTNVKNVAKPSTIFHTLLYIRQFILERNAINGIKTFTWSSSPHKHRRTHTGEKPYKCEECGKAFTASSTLSEYKTIHTGEKPCKCEECGKAFNWSSDFNKHKRIHSGQKPIL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Putative zinc finger protein 826.
What are the subcellular locations of this protein?
Nucleus.
Protein: MZM1_ASPFU
Sequence: MASQTAVTARSAYRQILRATRIAFQDDFRVLVAARQEARRQFDEHRREGIDTPMQINHAKEVAAILRHNIVQGVRDSNDENGKWELRIHDDIERGDNDSIRVGGKKVKVDKPCSA
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ISCSL_MYCTO
Sequence: MAYLDHAATTPMHPAAIEAMAAVQRTIGNASSLHTSGRSARRRIEEARELIADKLGARPSEVIFTAGGTESDNLAVKGIYWARRDAEPHRRRIVTTEVEHHAVLDSVNWLVEHEGAHVTWLPTAADGSVSATALREALQSHDDVALVSVMWANNEVGTILPIAEMSVVAMEFGVPMHSDAIQAVGQLPLDFGASGLSAMSVAGHKFGGPPGVGALLLRRDVTCVPLMHGGGQERDIRSGTPDVASAVGMATAAQIAVDGLEENSARLRLLRDRLVEGVLAEIDDVCLNGADDPMRLAGNAHFTFRGCEGDALLMLLDANGIECSTGSACTAGVAQPSHVLIAMGVDAASARGSLRLSLGHTSVEADVDAALEVLPGAVARARRAALAAAGASR
What is the function of this protein?
Catalyzes the removal of elemental sulfur from cysteine to produce alanine.
What are the official names of this protein?
Iscs-like cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
Protein: PURT_PROM0
Sequence: MKESIFSKKRILLLGSGELGKELVIESKRLGLEVIAIDRYEKAPAMQVADYSRVIDMGDKNILKNVIKEFNPDYVVPEIEALSIEALKELEDEGFNIVPNARTVEITMNRDKIRDLASKDLKIKTAKFDYIFEFDDLEKKADEIGFPLLLKPLMSSSGKGQSLVETKNDLQNAWKQAQANSRGKVKGVIIEEFINFDFEFTLLTVRKENGENIFCLPIGHLQSNGDYQCSWQPLEIKDSLIIEAKRMTSRILNNLNGAGLYGVEFFIKGSEVIFSELSPRPHDTGMVTLVSQNINEFELHLRAFLDLPIPHIYLIEPSATRVILSNQEYLNPIYEGLNEALEFEKTKVLIFGKPVSRKGRRMGVVLSSNSDIYLARKNADEAARKIKVSTT
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: EFG_STAAW
Sequence: MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNIIDTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAAPIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSELKEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDPYVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILESMEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMVSYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLIDVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQVVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_LARHH
Sequence: MFDVIAFLVQEYRDFSACPGPDDLARKLAAVGFEDDVIHDALDWLSSLLAQGAVPEVLAESRLPRILTQEEREGLPLEVQDFVLFLDRVAAVNNVQREQILDRLMDVPPDERSLDAARLTVLAVLWRHAAEVDALIAEELMVAIDGPMPLQ
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: RS21_SHEB8
Sequence: MPIIKVRENEPFDVALRRFKRSCEKAGILADVRAREFYEKPTTARKRAKAAAVKRLAKKLSRENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: AROQ_TOLAT
Sequence: MTAKFRILVLNGPNLNLLGKREPGIYGAATLDDIVGRLQQLAAELDVELTHKQSNAEYELVDTIHQAMGTVDFILINPAAFTHTSVAIRDALLGVAIPFIEIHLSNVHAREPFRHHSFLSDVAKGVICGLGADGYEFALTAAVRHLERSSNN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: CYB5S_TOBAC
Sequence: MGGQSKVFTLAEVSNHNNAKDCWLIISGKVYNVTKFLEDHPGGGEVLLSATGKDATDDFEDIGHSSSARAMLDEYYVGDIDSSTIPTKVKYTPPKQPHYNQDKTTEFIVKLLQFLVPLIILGVAFGVHFYTKQSA
What is the function of this protein?
Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.  May play a key role in the modification by desaturation of fatty acids in the endoplasmic reticulum, which in the developing seed is utilized for membrane synthesis and in the developmentally regulated production of large amounts of storage lipids.
What are the official names of this protein?
Cytochrome b5, seed isoform.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: U13_HHV6Z
Sequence: MAHAKKQARRKLLTSTDDPILSSTFTMRPTSKIADAEIISREHDYIASKTQADSKKKLSSLSVIFDKTVLFEFYGIGDNNEKAIVYPIDPDFLLCDSENNCTLSPFL
What are the official names of this protein?
Uncharacterized protein U13.
Protein: MIAB_YERPS
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLASTHGYQLTTIPEEADLLLLNTCSIREKAQEKVFSLLGQWKLLKEKNPQLIIGVGGCVASQEGEQLRQRAPCVDVIFGPQTLHRLPEMINHVQGTNSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTFCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAYRGATYDGDICSFAELLRLVAAIDGIDRIRFTTSHPIEFTDDIIDVYRDTPELVSFLHLPVQSGSDRILTMMKRAHTALEYKAIIRKLRQARPDIQISSDFIVGFPGETQQDFEQTMKLVADIHFDTSYSFIYSPRPGTPAADLPDNVSEEEKKQRLHILQQRISQQAMEISRKMVGTVQRVLVEGTSRKNVMELAGRTENNRVVNFEGSPDMIGKFVDVEIVNVYASSLRGILLRTEDQMDLRTHESPQSVIARTRKENEIGVGIYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_ECOK1
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: COXX_RHIEC
Sequence: MTVIDNHEALAEDGEMSEASARDYFELLKPRVMSLVVFTAFAGLVLAPGHINPVLGLIAILCIAVGAGASGALNMWYDADIDAIMSRTAKRPIPAGRIAPSEALAFGLVLSGFSVVILGLAVNWLSAAILAFTIFFYAVIYTMWLKRSTPQNIVIGGAAGAFPPMIGWACVTNSVTIESTVLFLIIFLWTPAHFWALALFKMRDYEAVGVPMLPNVSGERVTKHQIVAYAVLTAICAVLPSFLGFASFGYGLVAAALGAIFVYCSIAVWRMPDGDLKMIPAKKLFAFSIFYLFAVFSALMIDRLAAILVSQAGGSF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAA_ANOFW
Sequence: MENISDLWNKALAEIEKKISKPSFETWLKSTTAHSLKGDILIITVPNEFTKDWLESRYTRLIEQTLYDITGEELKIKCTIPNHQTTEEFDLKPTSKPRKHDDEQTEFPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVLEHNPSAKVVYLSSEKFTNEFINAIRDNRPDDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNTLHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGFDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKEINADLAAEALKDIIPSSKPKVITIQDIQRVVGEHFNVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDCSLPKIGEEFGGRDHTTVIHAHEKISALIQTDVQLQKQLKEIMEKLK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAT5_ARATH
Sequence: MASLMLSLGSTSLLPREINKDKLKLGTSASNPFLKAKSFSRVTMTVAVKPSRFEGITMAPPDPILGVSEAFKADTNGMKLNLGVGAYRTEELQPYVLNVVKKAENLMLERGDNKEYLPIEGLAAFNKATAELLFGAGHPVIKEQRVATIQGLSGTGSLRLAAALIERYFPGAKVVISSPTWGNHKNIFNDAKVPWSEYRYYDPKTIGLDFEGMIADIKEAPEGSFILLHGCAHNPTGIDPTPEQWVKIADVIQEKNHIPFFDVAYQGFASGSLDEDAASVRLFAERGMEFFVAQSYSKNLGLYAERIGAINVVCSSADAATRVKSQLKRIARPMYSNPPVHGARIVANVVGDVTMFSEWKAEMEMMAGRIKTVRQELYDSLVSKDKSGKDWSFILKQIGMFSFTGLNKAQSDNMTDKWHVYMTKDGRISLAGLSLAKCEYLADAIIDSYHNVS
What is the function of this protein?
Amino acid aminotransferase important for the metabolism of amino acids and Krebs-cycle related organic acids.  No activity with D-Asp or D-Ala as amino donors.  In plants, it is involved in nitrogen metabolism and in aspects of carbon and energy metabolism.
What are the official names of this protein?
Aspartate aminotransferase, chloroplastic, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast.
Protein: COBQ_SPHAL
Sequence: MAALMLQGTGSDVGKSVLVAGLCRALANRGLRVRPFKPQNMSNNAAVTIDGGEIGRAQALQALACRTPPHSDMNPVLLKPQADRTSQLIVHGRVRGTLGSGNFRAGRGALLPDVLESYGRLRRQCDIVIVEGAGSPAEINLRAGDIANMGFARAARVPVVLVGDIDRGGVIAAIVGTRTVIDAEDAAMIKGFVINKFRGDPALFDDGYRAIAERSGWPGLGVVPWLAAAARLPSEDAVILERRADAREGRRIVACPILPRIANFDDLDPLKQEPGVELLMVPPGQPIPAEAAIIVLPGSKATIADLAALRREGWDIDIKAHHRRGGLILGLCGGYQMLGTRIADPLGIEGAASEVEGLGLLDVTTELAPAKTLREVTGTAWNSPVAGYEMHMGATVGTDTARPFARIDGGGGEGAINAAGNVIGTYIHGLLASPALRSALLAKIGVAGNGRDHGADVDAALDDIAAELAIHIDIGALLRIAAHPV
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.