PharMolix/UniProtQA huggingface dataset:
Protein: CHLB_MARPO
Sequence: MKLAYWMYAGPAHIGTLRVASSFKNVHAIMHAPLGDDYFNVMRSMLERERDFTPVTASIVDRHVLARGSQEKVVDNITKKDKQEHPDLIVLTPTCTSSILQEDLQNFVNRASMSSDSDVILADVNHYRVNELQAADRTLEQVVRYYLEKAHRQEKLNLSLTDKPSANIIGIFTLGFHNQHDCRELKRLLQDLGIMINQIIPEGGFVENLHELPKAWFNLVPYREVGLMTALYLEKEFGMPYISTTPMGIVDIANCIRQIQKQVNIWSPILLGKKFDFEPYIDEQTRFISQAAWFSRSIDCQNLTGKKAVVFGDATHAASITKILACEMGIRVSCTGTYCKHDEEWFREQVQNFCDEILITDDHTEVGDMIARIEPSAIFGTQMERHIGKRLDIPCGVISSPVHIQNFPLGYRPFLGYEGTNQIADLVYNSFTLGMEDHLLEIFGGHDTKEVITKSLSTDTDLTWNSESQLELNKIPGFVRGKIKRNTEKFARQNNITKITVEVMYAAKEDLSA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FLIO_ECOLI
Sequence: MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGFAPKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEIPQTDFQSVMKNLLKRSGRS
What are the official names of this protein?
Flagellar protein FliO.
What is the protein family that this protein belongs to?
Belongs to the FliO/MopB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Bacterial flagellum basal body.
Protein: TM39A_XENTR
Sequence: MPGGRRGPSRQQLSRSALPSLQTLVGGTCGNGTGLRNRNGSAIGLSAPPITALITPEPVRHCHIPELPLDGGLLFEFLFFIYLLVALFIQYINIYKSVWWYPYNHPASCTSLNFHLIDYHLAAFITVMLARRLVWALISEASQVGTSSMVHYAALITARLVLLTLCGWVFCWTLVNLFRNHSVLNLLFLGYPFGVYVPLCCFHQDSRSQPLPTDCGYLVQDPLVDDGANGMATLVRPRDFLSLLRESLREQFNSTPSIPSHSCPLSPDLIRNEVECLKADFNRRIKEVLFNSLFSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLSTQLLPPKYCDLLHRSASHLGKWQKLEHGSYSNAPQHIWSENTVWPQGVLVRHSRSLYKAVGPYNVAVPSEVSHARFYFLFHRPLRLLNLLLIIEGSLVLYQLYSLLRAEKWNHTLSIALILFCNYYVLFKLLRDRIVLGRAYSYPISSYGLKPH
What is the function of this protein?
Regulates autophagy by controlling the spatial distribution and levels of the intracellular phosphatidylinositol 4-phosphate (PtdIns(4)P) pools (By similarity).  Modulates (PtdIns(4)P) levels by regulating the ER-to-Golgi trafficking of the phosphatidylinositide phosphatase SACM1L (By similarity).
What are the official names of this protein?
Transmembrane protein 39A.
What is the protein family that this protein belongs to?
Belongs to the TMEM39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SREA_EMENI
Sequence: MLASIPHMETLRSLPRNPDVVARHPSAEDLDAAQQLISSAQAGREHPQDRHYTDNGSRKSEAGAPHSHHEGEYPIVQTSETPMNGHHVEKTSPKSQKDTSFLGHSCSNCGTKSTPLWRRSPTGAMICNACGLYLKARNVARPTKRNRTQASPEAYHPQNQSVGSQPDPAVTGSEGCTGSCPGGGNCNGTGGAEGCDGCPAYNNRVYKSTARGNVAAHALNRAGNSDAVPSPEAEAPARNSGQPEGNMLVACQNCGTTVTPLWRRDENGHPICNACGLYYKLHGSYRPTTMKKTIIKRRKRVVPALRENSPTAATHSSHGSSASPEASSPATLAYSHDERHRYYSSEPVDQYHRISPAAQRPFGFAPPPVDFTNFNSGAVTLPHHPPPPRLLEPGHPPLSQFARRSISPSSSGNSKKRTLAEAGANTDTGPVPTTLEAGSNQLPPIVSSANPPPPARLSSISSILNHAHARDESRLDPSLAALGRQQQSQPHHPQSSPLAPTQAASQSLPGVSNMDNHVEDRRAKLQREAEEMREQLRAKERELAELAGQ
What is the function of this protein?
GATA-type transcription repressor that regulates iron- acquisition genes through specific binding GATA sequence elements of target promoters (PubMed:9988696, PubMed:11555288).  Iron acquisition regulation is critical for survival under both iron-limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity) (PubMed:11555288).  SreA targets include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis (PubMed:11555288, PubMed:12196195, PubMed:12487628).
What are the official names of this protein?
GATA-type transcription factor sreA, Siderophore uptake regulator sreA.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROC2_BACC1
Sequence: MRYITAGESHGPQLTVILEGVPAGLTLAAEHINKELLRRQKGHGRGRRMQIETDTVEIVSGVRHGVTLGSPITLIVKNDDFKHWTKVMGAEPISEKESKDMKRTITKPRPGHADLNGAIKYGHRDIRNVLERSSARETTVRVAAGAVAKQILKELGVEIAGHVLEIGGVKAKHISNLSIEEIQTITENSPVRCLDKEVEQEMMNAIDHAKSSGDSIGGIVEVIAEGMPIGVGSYVHYDRKLDAKLAGAIMSINAFKGAEIGVGFEAARQPGSKVHDEILWDEEQGYTRKTNNAGGLEGGMTTGMPIVVRGVMKPIPTLYKPLASVDIDTKEAFQASIERSDSCAVPAAGVVAESVVAWELAHALVEQFGKDRMELIQQNITQHNKYAKEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase 2, CS 2, 5-enolpyruvylshikimate-3-phosphate phospholyase 2.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HISX_AROAE
Sequence: MTAPAAAIRRLDAREPEFLATLDALLAFEGGADARIDAAVSEILRAVRTTGDAAVLEYTRRFDHLDVKSMVQLELSKSELKAALDSLTVEQREALRVAADRVRVYHERQRAESWDYVEADGTRLGQKVTPLDRVGLYVPGGRASYPSSVLMNAIPAKVAGVGELIMVVPTPNGEKNPLVLAAAAITGVDRVFTIGGAQAVAALAYGTQTLPQVDKIVGPGNAYVAEAKRRVFGTVGIDMVAGPSEVLIISDGSGQAGWVAMDLFAQAEHDELAQSILLCTDAGFIDAVAASIERLLPSMPRRETIAASLANRGALIHVDSLEQACAIANRIAPEHLELSLDDAEPWIGRIRHAGAIFVGHWSVEALGDYCAGPNHVLPTMRSARFSSPLGVYDFQKRTSIVQISEAGAQTLGRVASILARGEGLQAHARSAEMRLHDR
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: PHAR2_RAT
Sequence: MGQTSVSALSPQPGSVDGLDKASIANSDGPPAGSQTPPFKRKGKLSTIGKIFKPWKWRKEKTSDKFRETSAVLERKISTRQSREELIRRGLLKELPDQDGDVTVNFENSNGHMIHIGEEATQEENVGKPEEGNVSVCEKGPPREEQAEEKTAGSSHPKKTTGSKASSSPSASSTSSHPRGPKESLTGKAGAVGTTRGKKKISKQPAAAASRLSPNTVTSETSSLKGELSDTGVESLKPEETVAGAEEEATGKPKAVVVALPPVTVPPSSPALPLPPEDPCTIALDTPMVLVSDGPTLPISALETSPLPGTEEPANRTTPYSSTGLGGSREQAKCFTTKDGLGKAGPQLLTPGQMGDSLESFSAPEDEAPREYQANDSDSDGPILYTDDDDEEDDDDDSTGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQELRQQIGTKLVRRLSQRPTTEELEQRSILKQKNEEEEQEAKMELKRRLSRKLSLRPTVPELQARRILRFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRFHRP
What are the official names of this protein?
Phosphatase and actin regulator 2.
What is the protein family that this protein belongs to?
Belongs to the phosphatase and actin regulator family.
Protein: IGSF5_MOUSE
Sequence: MEGSWRDVLAVLVILAQLTASGSSYQIIEGPQNVTVLKDSEAHFNCTVTHGWKLLMWTLNQMVVLSLTTQGPIITNNRFTYASYNSTDSFISELIIHDVQPSDSGSVQCSLQNSHGFGSAFLSVQVMGTLNIPSNNLIVTEGEPCNVTCYAVGWTSLPDISWELEVPVSHSSYNSFLESGNFMRVLSVLDLTPLGNGTLTCVAELKDLQASKSLTVNLTVVQPPPDSIGEEGPALPTWAIILLAVAFSLLLILIIVLIIIFCCCCASRREKEESTYQNEIRKSANMRTNKADPETKLKGGKENYGYSSDEAKAAQTASLPPKSAEVSLPEKRSSSLPYQELNKHQPGPATHPRVSFDIASPQKVRNVTLV
What is the function of this protein?
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells.  Mediates calcium-independent homophilic cell adhesion.  In testis, it may function as a cell adhesion molecule rather than a tight-junction protein.  It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.
What are the official names of this protein?
Immunoglobulin superfamily member 5, IgSF5, Junctional adhesion molecule 4, JAM-4.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction.
Protein: ATPE_CHRVO
Sequence: MSKMRVEVVSTEQLIFSGEAEFVVAPATEGEIGVYPQHVPLLTRIKPGVLRLKVPGTKEEVLVAVSGGMMEVQPSLITVLADTAIRGEDLDEARANEAKRAAEDALKHATDDMSTAKAHAALAVAIAELKTLDYLKKRAH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAPB_CERS1
Sequence: MSDLPGIVVTGASGRMGQMLMKTVLASGKARLVGAVERPGSDWVGRDAGAAMGGAAIGVTVTDDPLAAFAQAQAVIDFTAPEATVQFAELAAQARAVHVIGTTGLEPVHLERLAWAAHHAVIVRAGNMSLGVNLLTRLTQKVAEALDEDWDIEVVEAHHRMKVDAPSGTALMLGEAAARGRGVDLAQARVSGRDGITGPRAPGSIGFSAIRGGDIVGEHDVIFAAAGERITLRHVATDRAIFARGALKAALWGQDKRPGQYDMMDVLGL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_MYCVP
Sequence: MAVPKRRMSRANTRSRRAQWKATATNLVGVTVAGQQRKVPRRLLKAARLGLIDLDRR
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: AMPA_XYLFM
Sequence: MALQFQLNQTTPQTVTTDCVIVGIYADKTLSPTAKTLDAASGGRITALTARGDLTGKSGTSALLHDLNGVTAPRVLVVGLGEADKFGAGQYIKAVGDAVRALKDAPVTHALLTLSELPVKDRNAAWNIHQAVIAADHAAYRYTATLGTSRKKAEESGLITLAIHGQETSGLTLGQAIAEGVEYARALGNLPPNICTPAYLAETTAHFAATHPGATCEILDESNMEALGMGALLAVARGSANRPHLIVLKWNGGGDARPYVLVGKGITFDTGGVNLKTQGGIEEMKYDMCGGAAVIGTFVAAVKVRLPLNLIVIVPAVENAIDGNAYRPSDVITSMSGKTIEVGNTDAEGRLILCDALTYAERFKPEALIDVATLTGACMIALGRAATGLMTHHDDLANELLTAGEHVHDRAWRLPLWDEYQNLLDSTFADVYNIGGRWGGAITAGCFLSRFTEGQRWAHLDIAGSASNEGKRGMATGRPVGLLTQWLVDRC
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRT_ECOUT
Sequence: MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRGTSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWMMESVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGEQLVAK
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORC_METJA
Sequence: MIEIRFHGRGGQGAVTAAQILAKAAFYDGKFCQAFPFFGVERRGAPVMAFTRIDDKKITLRCQIYEPDYVIVQDATLLESVNVVEGLKKDGAVVINTVKDDLDLGYKTYTIDATGIALDVLGVPIVNTAMVGAFAGVTGIVSIESVKKAILDTFKGKLGEKNAKAAEVAYNEMLKKYG
What are the official names of this protein?
Pyruvate synthase subunit PorC, Pyruvate oxidoreductase gamma chain, POR, Pyruvic-ferredoxin oxidoreductase subunit gamma.
Protein: EC12_ARATH
Sequence: MASNTSFLFATIAILLVLNISGRTLPETEDSTNIAARLNGGGLMECWNALYELKSCTNEIVLFFLNGETKLGVDCCQAVEVITTDCWPAMLTSLGFTSDETNVLRGFCQSPNSGGSSPAPSSVKL
What is the function of this protein?
Involved in the regulation of gamete interactions during the double fertilization and to prevent multiple-pollen tube attraction; mediates the redistribution of the gamete fusogen HAP2/GCS1 to the cell surface after secretion upon sperm arrival.
What are the official names of this protein?
Egg cell-secreted protein 1.2.
What is the protein family that this protein belongs to?
Belongs to the plant egg cell-secreted peptide family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Secreted. Note=Secreted via vesicle exocytose upon sperm arrival, especially in the apical region of the degenerating synergid cell.
Protein: AROA_THET2
Sequence: MDAFRLAPCGPLRGRLRVPGDKSVTHRGLMLLALAEGEGRLFYPLKAGDTLSTARVLQALGAEVREEGPHFLVRGRGLRFKEPEDVLDCGNAGTLMRLLLGLLAGQEGLFAVLTGDASLRRRPMGRVVAPLRAMGARVDGREEGERAPLAVRGAPLRGLRYTLPVPSAQVKSALLLAGLFAEGVTEVEEPTPTRDHTERLFRHFGLPLEVEGRRVRTWRTGPFPAKDLVVPGDFSSAAFFLVAALVTPGSEVVVEGVGLNPTRTGLLTVLKAMGADLEWRVLEGEAGEPVGWVRARHSLLKGVAVDPGLIPLMVDEVPVLAAAAAWAEGETYIPGLSELRVKESDRVRAIAENLRALGVEVEEGPDWLRIRGGGVRPGRVRPFHDHRIAMAFAVVGLPVGVEVEEPHWAEISYPGFFQDLLRLCAAS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAO15_MYCTT
Sequence: MPASLLRFLALAGTAVGLTTNHNHSPSCRVLPGDAAWPSSRDWAKLNKTLNGHLIATVPQASVCHKSPFGQYDAQACEELKSSWDISTITHVNAPGDVLSQNFQNYSCVPFTDPSQPCQLGNYPSYVVNVTGAADVQAALKFAQKHNVRIVIKNTGHDYLGKSTGKGALSLWMHNLKSTKFIKNYKAPYYKGPAAKLGAGVEGFEAYAMANSTGHRIVGGTCPTVGIVGGYTQGGGHSILSSSYGVAADNVLEWEVVTADGRHLVATPTRNSDLYWALSGGGGGTFAVVLSMTARLHRDGIVGGTLLGFNDSAVGNEVYWEAVAAFHALLPDFLDGGNSFTYSVGNNSLTAYGTMPGADRDAVDRLLRPFLDDLASRGITPVVQPRVSTNYYDHFFTYLGPAPYGNAAYFPFTNSRIIPRSLVTDPKSNAVVTDLFRNISQVPAFSPFYCDSFSVADKPHPANSLHPAWRTGMLLCAPAGSWDWDASPEEMAARDRYAAETLQPMMDAATPGGSVYLNEANHLYANWKESFYGDNYARLLRVKKKYDPDSVFYVKTGVGSEVWDVDATGRLCRA
What is the function of this protein?
Probably oxidoreductase that, when reduced, rapidly reacts with molecular oxygen, a hallmark of flavoprotein oxidases.  A large panel of alcohols, including carbohydrates, steroids and secondary alcohols were tested as potential substrates, but none has been identified so far.
What are the official names of this protein?
VAO-type flavoprotein oxidase VAO615.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNME_MOOTA
Sequence: MLDDTIAALATPPGEGGISIIRLSGSQAIAIVAKVFKPVKGPDLTTTRSHTLRLGFIIDPVSGESLDEVLVSVMRAPHSYTAEDVVEINCHGGALATSRVLQLVLRTGARLAEPGEFTRRAFLNGRLDLAQAEAVLEIIRARSSRGLTAALDHLRGNLSRKIGELNERLTGILAALEASMDFPEEVGEVDPENLADLRRILAGVDRLLATWEEGRLLTEGLKVAIVGRPNVGKSSLLNALLNQERAIVSNIPGTTRDTIEETLQLGGFTCRLIDTAGLRETADELESIGVARSKKAIAAADLVLVVVDLQTGIQDEDRRVLESVRDKVLIIIGNKLDLVAHDINKKLADLESFAGNYPRVAVSALKGKGLDELARKVQEIVLGGRALAGSDEPLITNARHRAALENCREHLASAIKAWEEGLPEDLIAIDLWSAADYLGEIIGTTAREDLLDRIFSDFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_GALSU
Sequence: MRITQGTFSFLPDLTDEQIKKQIDYMISKKLAIGIEYTNDIHPRNSFWEMWGLPLFEVTDPAPVLFEINACRKAKSNFYIKVVGFSSERGIESTIISFIVNRPKHEPGFNLIRQEDKSRSIKYSIQAYETYKPEDQRY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.  Carbon dioxide and oxygen bind in the same pocket of the enzyme in a similar manner (PubMed:23112176).
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PEX11_SCHPO
Sequence: MAVIFENPQYVHVLRMLNSMPARDKTFRALQFVAKLLSWHLFYGGSSLSTVNKWKKLESNISFSRKLFSIGKVLDYICKVYFDSLKLQNPLSGNKSALPTISFTKDVAFAGYATAELIGWFNKTELMPCSHSKQISTIGKQCLAVALLSSCLAGCYELQQNSKKIKSATQEASEKDSTSLQTLQKERKEILFFALQNALDATIPLAELDILKVNDGFVAAAGITTSLMSVYKTWIGSY
What is the function of this protein?
Involved in peroxisomal proliferation.  Promotes peroxisome division and biogenesis (By similarity).
What are the official names of this protein?
Peroxisomal biogenesis factor 11.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.
What are the subcellular locations of this protein?
Mitochondrion. Peroxisome membrane; Peripheral membrane protein.
Protein: EGR1_BOVIN
Sequence: MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLSNGAPQFLGAAGAPEGSSGSSSGSSGGGGGGGGGSSSSNSNSSSAFNPQGEASEQPYEHLTAESFPDISLNNEKVLVETSYPSQTTRLPPITYTGRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPATSSSASSPAASSSASQSPPLSCAVQSNDSSPIYSAAPTFPTPNTDIFPEPQGQAFPGSAGPALQYPPPAYPGAKGGFQVPMIPDYLFPQQQGDLGLGTPDQKPFQGLESRTQQPSLTPLSTIKAFATQSGSQDLKALNSTYQSQLIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIRIHTGQKPQCRISMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADKSAASAATSSLPSYPSPVATSYPSPATTSYPSPATTSYPSPVPTSYSSPGSSTYPSPVHNGFPSPSVATTYSSVPPAFPTQVSSFPSSAVTNSFSASTGLSDMTTTFSPRTIEIC
What is the function of this protein?
Transcriptional regulator.  Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity).  Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity).  Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia.  Plays a role in the regulation of cell survival, proliferation and cell death.  Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor formation.  Required for normal progress through mitosis and normal proliferation of hepatocytes after partial hepatectomy.  Mediates responses to ischemia and hypoxia; regulates the expression of proteins such as IL1B and CXCL2 that are involved in inflammatory processes and development of tissue damage after ischemia.  Regulates biosynthesis of luteinizing hormone (LHB) in the pituitary (By similarity).  Regulates the amplitude of the expression rhythms of clock genes: BMAL1, PER2 and NR1D1 in the liver via the activation of PER1 (clock repressor) transcription.  Regulates the rhythmic expression of core-clock gene BMAL1 in the suprachiasmatic nucleus (SCN) (By similarity).
What are the official names of this protein?
Early growth response protein 1, EGR-1.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NS2_HRSVA
Sequence: MDTTHNDNTPQRLMITDMRPLSLETIITSLTRDIITHKFIYLINHECIVRKLDERQATFTFLVNYEMKLLHKVGSTKYKKYTEYNTKYGTFPMPIFINHDGFLECIGIKPTKHTPIIYKYDLNP
What is the function of this protein?
Plays a major role in antagonizing the type I IFN-mediated antiviral response (PubMed:15047850).  Acts cooperatively with NS1 to repress activation and nuclear translocation of host IFN-regulatory factor IRF3 (PubMed:15827150).  Interacts with the host cytoplasmic sensor of viral nucleic acids RIGI and prevents the interaction with its downstream partner MAVS (PubMed:19193793).  Together with NS2, participates in the proteasomal degradation of host STAT2, IRF3, IRF7, TBK1 and RIGI through a NS-degradasome involving CUL2 and Elongin-C (PubMed:17251292, PubMed:23877405).  The degradasome requires an intact mitochondrial MAVS (PubMed:23877405).  Induces host SOCS1 expression (PubMed:26557722).  Induces activation of NF-kappa-B.  Suppresses premature apoptosis by an NF-kappa-B-dependent, interferon-independent mechanism promoting continued viral replication (PubMed:17151097).
What are the official names of this protein?
Non-structural protein 2, NS2, Non-structural protein 1B.
What is the protein family that this protein belongs to?
Belongs to the pneumovirus non-structural protein 2 family.
What are the subcellular locations of this protein?
Host mitochondrion. Note=Most NS2 resides in the mitochondria as a heteromer with NS1.
Protein: DLTA_STRP3
Sequence: MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAALIDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPSLIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPKGVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFALPKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELTVSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDNILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIVVKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINEVNNR
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_CMVIX
Sequence: MAFQGTSRTLTQQSSAATSDELQKLLFSPEAIKKMATECDLGRHHWMRADNAISVRPLVPEVTHGRIASFFKSGYDAGELSSKGYMSVTQVLCAVTRTVSTDAEGSLRIYLADLGDKELSPIDRQCVTLHNHDLPALVSFQPTYDCPMESVGNRKRCFAVVIERHGYIEYTGTTASVCSNWQARFSSKNNNYTHIAAGKTLVLPFNRLAEQTKPSAVARLLKSQLNNIESSQYVLTDAKINQNARSESEEIIVESPPIVIGSSSASRSEAFRPQVVNGL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
Movement protein, MP, Protein 3A.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles into long tubular structures at the surface of the infected protoplast.
Protein: TREA_SALPA
Sequence: MIPPEIRRSVLLQKAIKLALAGTLLTFASFSATAADPSSDTETPQPPDILLGPLFNDVQNAKLFPDQKTFADAIPNSDPLMILADYRMQRNQSGFDLRHFVDVNFTLPKAGEKYVPPAGQSLREHIDGLWPVLTRSTKNVEKWDSLLPLPESYVVPGGRFREIYYWDSYFTMLGLAESGHWDKVADMVANFGYEIDAWGHIPNGNRTYYLSRSQPPFFAFMVELLAQHEGDDALKEYLPQLQKEYAYWMEGVETLQPGQQNQRVVKLEDGSVLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLSTIRTTTIVPVDLNALLYQLEKTLARASAAAGDRAKASQYDALANARQKAIEMHLWNNKEGWYADYDLQNNKIRDQLTAAALFPLYVNAAAKDRAVKVAAAAQAHLLQPGGLATTSVKSGQQWDAPNGWAPLQWVAAEGLQNYGQDDVAMEVTWRFLTNVQHTYDREKKLVEKYDVSSTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPQEKPCDSVPSTRPASLSATPTKTPSAATQ
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.