PharMolix/UniProtQA huggingface dataset:
Protein: RL19_METSB
Sequence: MNIIAELEAEQAAKLLAGKTIPEFQPGDTVIVNVKVKEGERTRVQAYEGVCIARNGGGLNESFTVRKISYGEGVERVFAIYSPNIDSIKVVRRGKVRRAKLYYLRDRRGKSARIAEKMESPAAKATREAAKKEAKAAKKNAAPAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: Y1213_METKA
Sequence: MTRAVVTVIGADRPGIVAGISSVLAEHNANIEDISQTVLRDLFAMVMLVDLSEADVSVGKLREELQKAGEELGVDVIVQHEDVYRAMHRV
What are the official names of this protein?
UPF0237 protein MK1213.
What is the protein family that this protein belongs to?
Belongs to the UPF0237 family.
Protein: RT12_MAGSO
Sequence: MPTLNQLIRHGREEKRRTDRTRASDQCPQKQGVRPRVPTRTPKKPNSAPRKIAKVRLSNRHDIFAHIPGEGHNSQEHPMVLIRGGRVKDSPGVKSHRIRGVKDLLGIPNRRRGRSKYGAERPKSI
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYH_ENDTX
Sequence: MNYKAPRGTHDIFGINASGMSWLEQKAKVIFKRHGFEEVRTPVFEDAALFMRSIGQTTDIVEKEMYIFEDRKKRKLALRPEGTASLVRAFIEHRMDVSMPAGRFFYMGEMFRYERPQAGRYRQFHQIGAEFFGSSSPAADAEIIILAQHLLSSVGINEMNIYINSLGCEKCRPFFRETLVKYLGSVRDLCEDCLRRLEKNPLRILDCKTDSNKFTAVPRMSDYLCNCCKDNFSLTQSLLKSVGYNYTVDERLVRGLDYYTKTVFEIRSDAVGSQCALAAGGRYDNLVGELGGQDTPAVGFALGSERVLLAVQKTGFFGSFQESEKIFIAVADQELFSEAFSFAVKAMRNGLKGNKNISVFGPINGKSLTSQLKFADKIKAVKTIVFARTEFEYGKFLMKNMKDKTQTEFLISEF
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_AERS4
Sequence: MKAQDLRQKSVDELNQELLGLLREQFNMRMQASTGQLAQTHTLKQVRRDVARIKTVLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: GHRB_ECOK1
Sequence: MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUS8_BOVIN
Sequence: MRCLTMPMLLRALAQAQAARAGHASVRGLHSSAVAATYKYVNLREPSMDMKSVTDRAAQTLLWTELIRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAVCPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:10852722, PubMed:18721790).  Essential for the catalytic activity and assembly of complex I (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, Complex I-23kD, CI-23kD, NADH-ubiquinone oxidoreductase 23 kDa subunit, TYKY subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ARLY_METS4
Sequence: MSNRMWGGRFASGPAEIMEEINASIGFDKRLAPQDIRGSLAHVAMLGKTGILPQADVAAIEAGLKTVQAEIESGAFTFQRALEDIHMNVESRLTELVGPAAGRLHTARSRNDQVATDMRLWVRDTLDALDAQAADLQRALAALALAHSGTVMPGFTHLQSAQPVTFGHHLLAYVEMLGRDRGRFRDARARLNECPLGAAALAGTSFPIDRHATAAALGFDRPTANSLDSVADRDFALEALAAAAIAAVHLSRFAEEIVVWTSAQFGFVRLSDRYTTGSSIMPQKRNPDAAELVRAKAGRVIGALAGLLIVMKGLPLAYSKDMQEDKEGTFDALQTLSLCLAAMTGMVRDLEPVPEVLKAAAGAGYATATDLADWLVRELGLPFRDAHHVTGRLVGRASARGVGLEALSLAEMREEEPRITEAVYAVLGVENSVASRTSYGGTAPANVRAQAERWLAALGDTQ
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_RHIE6
Sequence: MTVLTIEEMAATLAPGQAIAGLDLGTKTIGLSMSDLGRRFATPRPVIRRAKFTIDAQALLDFAAKERVAGFVIGLPMNMDGSAGPRVQATRAFVRNMEEKTALPFVYWDERLSTVAAERTLLEMDVSRAKRAERIDSAAASFILQGALDRLSLLARSDGDEFSA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPC25_DROTE
Sequence: MAIIIPESSYERRVKALYEKQIRMEALEGKFIKKVYKFNSNLLDVKEAVLRHQRKVGKLQKVVMERREELEKRVSFMEELAQELEATKLRNLAMKEQIKQRKMIARQRKNEIMERIQTLSKTTGTYVNQEALPARVKGVTVLRGDKRDQLIPFDLNATDAEGLNSLCQHLESLNVDVSQWQQLVSLAMDVAMEARAPTTPPKEVANCKSIIEIDLTSPTSHQA
What is the function of this protein?
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Kinetochore protein Spc25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: QOR_LAMGU
Sequence: MATGQRLMRAIRVSEFGGPEVLKLQSDVAVPIPEEHQVLIKVQACGVNPVDTYIRSGTYSRKPRLPYTPGLDVAGLIEAVGERVSAFKKGDRVFTTSTVSGGYAEYALAADHTVYKLPGELDFQKGAAIGVPYFTAYRALLHSACAKAGESVLVHGASGGVGLAACQIARACCFKVLGTAGTEEGQRVVLQNGAHEVFNHREDINIDKIKKSVGEKGIDVIIEMLANVNLSNDLNLLSQGGRVIIVGSKGPVEINPRDTMTKESSIKGVTLFSSTKEEFQQFAAALQAGMEIGWLRPVIGSQYPLEKVAQAHEDLTHSSGAAGKVVLLLK
What is the function of this protein?
Does not have alcohol dehydrogenase activity.  Binds NADP and acts through a one-electron transfer process.  Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro).  May act in the detoxification of xenobiotics.  Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability.  NADPH binding interferes with mRNA binding (By similarity).
What are the official names of this protein?
Quinone oxidoreductase, NADPH:quinone reductase, Zeta-crystallin.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_VIBCM
Sequence: MEQFNVWFTVSEVQGLVKSGGLADVAKALPQALKALHQQVAIALPAYRSVPGKEDAELVLETELTHWPHTQYRVLKRDLDGVPIYLIDCPAYFDRPALYAENNQAYADNGERFGFFSAACLDVLPKLGIQPDIIHANDWHTGLVPFLLKTRYRYDSFFEQVKSVLTVHNAIFKGIFSYHQLEVIPELNLSGMEFLQYGHDHVSMLRAGIAFADKVNAVSPNYAAELLTPLGAHGLVDDFVRRARDLHGIVNGCDYSEWNPRTDHYLPATYSDEPESMRKGKALCKTALQEELHLPVTDVPLFGMVCRLTHQKGFHYLLPILEQFLRNNVQVVIVGTGEPEVAARLNKIAHYHRAKFAFVETYSERLAHWVEAGSDFFLMPSEFEACGLNQIYSMAYGTLPIVREVGGLKDTVNDYDKFPERATGFGYQEPTPEALLITMQRALLFYLQQPEEMLKVQQRAMQQNFSWEESAQEYMKMYRLARFG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: Y696A_SULTO
Sequence: MRIKDAIIKIFYTRKDVSEIYLVIRDRVKGTSEIPFSNIERVDNYYIYLNDGETVIPLHRVIEIREKDKTLWKR
What are the official names of this protein?
UPF0248 protein STK_06965.
What is the protein family that this protein belongs to?
Belongs to the UPF0248 family.
Protein: GE_HHV11
Sequence: MDRGAVVGFLLGVCVVSCLAGTPKTSWRRVSVGEDVSLLPAPGPTGRGPTQKLLWAVEPLDGCGPLHPSWVSLMPPKQVPETVVDAACMRAPVPLAMAYAPPAPSATGGLRTDFVWQERAAVVNRSLVIHGVRETDSGLYTLSVGDIKDPARQVASVVLVVQPAPVPTPPPTPADYDEDDNDEGEDESLAGTPASGTPRLPPPPAPPRSWPSAPEVSHVRGVTVRMETPEAILFSPGETFSTNVSIHAIAHDDQTYSMDVVWLRFDVPTSCAEMRIYESCLYHPQLPECLSPADAPCAASTWTSRLAVRSYAGCSRTNPPPRCSAEAHMEPVPGLAWQAASVNLEFRDASPQHSGLYLCVVYVNDHIHAWGHITISTAAQYRNAVVEQPLPQRGADLAEPTHPHVGAPPHAPPTHGALRLGAVMGAALLLSALGLSVWACMTCWRRRAWRAVKSRASGKGPTYIRVADSELYADWSSDSEGERDQVPWLAPPERPDSPSTNGSGFEILSPTAPSVYPRSDGHQSRRQLTTFGSGRPDRRYSQASDSSVFW
What is the function of this protein?
The heterodimer gE/gI serves as a receptor for the Fc part of host IgG.  Dissociation of gE/gI from IgG occurs at acidic pH.  May thus be involved in anti-HSV antibodies bipolar bridging, followed by intracellular endocytosis and degradation, thereby interfering with host IgG-mediated immune responses.
What are the official names of this protein?
Envelope glycoprotein E, gE, gE-1.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein E family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host cell junction. Host Golgi apparatus membrane; Single-pass membrane protein. Host endosome membrane; Single- pass membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans- Golgi network (TGN), maybe through an interaction with PACS-1 sorting protein. The heterodimer gE/gI then redistributes to cell junctions to promote cell-cell spread later in the infection.
Protein: FETP_FRATH
Sequence: MTKVFCKKYHQELDAIPFQPLPGELGKKIHNEISNKAWQAWLAHQTILINEYRLNLIEPKAKEFLKEEMYKFLFEGKEEKPEQFSEI
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: Y277_HAEIN
Sequence: MSEISTALSLENCPCQSSHHYADCCGKFHLRQAFPETAEQLMRSRYTAYVLKNIPYIVVTTVPSQQTLLKPRLLQEWADNTTWLGLEILKTESLTKTQSAVEFKAIFQGEECEQAHQERSIFVKIEDRWYFVDPTVSLPTMKQPCVCGSGKKFKHCCGGFL
What are the official names of this protein?
UPF0225 protein HI_0277.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: HLDD_SALCH
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMSGEELGDIEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLERGIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVAAVNLWFLESGKSGIFNLGTGRAESFQAVADATLAYHKKGSIEYIPFPDKLKGRYQAFTQADLTNLRNAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: RRAA_YERPN
Sequence: MKYDTSDLCDIYHEEVNVVEPLFSNFGGRTSFGGKITTVKCFEDNGLLFDLLEENGLGRVLVVDGGGSVRRALINAELAELALKNEWEGIVVYGAVRQVDDLAELDIGIQAMAAIPVGAADEGVGESDIRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LNT_GLOVI
Sequence: MSGIALRRRREQAQRRRSIAGVLAAVGGGTALGLAAPPTGWGVLVWVALVPLLVYLRAEHRPRAFWLGTLAGMVYYAILLRWLLGFHPLTWLGIEWWPSLAIALGAWLFVSASQAWVIGLWASLVVRTRLSGLRRVLFAVGLWVGLHWLWGQGETAFPWGTLAQSLAGDLWAVQTVALGGAQLLVGLAVAVNALVAESWSTRRVGYAGLAALLAASVYLYGWWQLAQPLPAGEPLRMGVIQGNIAQARKWTPDGRRETVETYVRGYEELAAAGAQLVLTPETAFPFIWSRPTNPAAPLVPEIQSRRVPVLLSAFERRTDGQVATTLFALDGDARTISTFNKIHLVPFGEQIPLKALIGPLVRKLSPVQQEVFAGSLGQRLQTPVGLVAAGICFDSAFADGFRAQVAAGARLLVQSTNDAWYGPAMAPQHHALDALRAVETGRYLVRASNNGTSAVVDPLGRTTRITGWNVYAAFVEPVRLLEGMTLYALWGDWFVPLSAALALLGLIAGRSPAGRRGRRNF
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SKI8_BOVIN
Sequence: MTNQYSILFKQEQAHDDAIWSVAWGSNKKENSETVVTGSLDDLVKVWKWRDEKLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYDCPI
What are the official names of this protein?
SKI8 subunit of superkiller complex protein, WD repeat-containing protein 61.
Protein: SNPH_HUMAN
Sequence: MAMSLPGSRRTSAGSRRRTSPPVSVRDAYGTSSLSSSSNSGSYKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIKQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGMAKEDGTGESAGGSPARSLTRSSTYTKLSDPAVCGDRQPGDPSSGSAEDGADSGFAAADDTLSRTDALEASSLLSSGVDCGTEETSLHSSFGLGPRFPASNTYEKLLCGMEAGVQASCMQERAIQTDFVQYQPDLDTILEKVTQAQVCGTDPESGDRCPELDAHPSGPRDPNSAVVVTVGDELEAPEPITRGPTPQRPGANPNPGQSVSVVCPMEEEEEAAVAEKEPKSYWSRHYIVDLLAVVVPAVPTVAWLCRSQRRQGQPIYNISSLLRGCCTVALHSIRRISCRSLSQPSPSPAGGGSQL
What is the function of this protein?
Inhibits SNARE complex formation by absorbing free syntaxin-1.
What are the official names of this protein?
Syntaphilin.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Synapse, synaptosome.
Protein: TNR5_HUMAN
Sequence: MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGPQDRLRALVVIPIIFGILFAILLVLVFIKKVAKKPTNKAPHPKQEPQEINFPDDLPGSNTAAPVQETLHGCQPVTQEDGKESRISVQERQ
What is the function of this protein?
Receptor for TNFSF5/CD40LG (PubMed:31331973).  Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40.
Protein: GLPK_BORGP
Sequence: MKYILSIDQGTTSSRAIVFDKHANIKGLAQKEFTQIYPQPSWVEHDPTEIWGSQLGVITEALANSRILPNEVDAIGITNQRETTVIWEKSTGKPIYNAIVWQDRRTAKICDQLTKEGKDKIILEKTGLVLDSYFSGTKILWILDNVEGARQKAENGELCFGTIDTWLLWNLTQKKVHATDYSNASRTLLLNIKTLEWDDELLKILNIPKAILPELKESSTIYGETDKSIFGAEIPIAGIAGDQFAATFGQACLKKGMAKNTYGTGCFLTVNIGKEPIINHERLLTSIAWGRKKTVTYVLEGSVFIGGAVIQWLRDGLEFFRKSSDAESLASSASDNGGVYFVPAFVGLGAPHWDSYARGTIIGITRGSTKAHITRAALESIAFQSFDILNTMKKSIPNFEIKELRVDGGASQNNLLMQFQADLLECKVVRPKITETTALGAAYLAGLASGYWQSAEEIISLWQVDKIFEPSMPKNQKEKLLENWNRAIERSKSWIQNSNSL
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: LRGA_STAAC
Sequence: MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHED2_BURTA
Sequence: MGYHFYFDREFGRQAVRVNPGGFAIASADVMLATVLGSCVSVCMFDSAARVGGMNHFMLPGSGNGARNDSLSSLYGVNAMELLINGLLRRGALKWRLRAKLFGGGCVMQSLSDTRIGERNAAFVRAYLDAEGIRSVGGDMLGTRPRRVCYFPSTGRALCKRLVRGSDVADIATSERAYDGDLARRLPVAGSVELF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD 2.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: NUCKS_BOVIN
Sequence: MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPAKKIRSSPREAKNKRRSGKNSQEDSEDSEEKDVKTKKDDSHSAEDSEDEKEDHKNVRQQRQAASKAASKQREMLMEDVGSEEEQEEEDEAPFQEKDSGSDEDFLVEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPTASKASKEKTPSPKEEDEEPESPLEKKASSSPPPEKSGDEGSEDDAQSGED
What is the function of this protein?
Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR).  Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures, but with less affinity than RAD51AP1.
What are the official names of this protein?
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SEC16_COCIM
Sequence: MAEDRVLGHESGLFTDAIHLGAWNPAHRPEDFSDSVLHEVATQTSVPIQTPDLAPCPPTEFELEHRDPEASPPDNVLDETKDVEYLQAFPEAPTRLENSGHVDITGSEYMQSIEKTREGAVIDSNNGSPFIDSFKGSDDDTGTNTFPDDNIDFQAMIGQTHDDTRDVWDRSTDAHVEDLSTQLVTEPYSAENDKVNSWNSVFADDEGGGDFFSQISSQSKPTVAHLESEPRSDDMASHLSNGNVQPSNESQQTKAIDSLFQEDESTGEADFFNSQGPAHVEPSLELLSETQPNSMPEDHPLPSLDPGKELPHHQSVAVVQDEKPEVIRPAEPGVAENLGEEELAERWKAFLGDDDILIENETLDGSIEGANTHTAEYQRHPVQPASQVGSEQPPVNTYTPHQPSSSEMLGGLPAAGYSSTLGNLTNPEKSKVESFSNQSKAGYQSPYDLPFDMRPKHAPPRKIAPPVGVNPPPRSSSMSGSRPPSSSYMVPGPNFSPVAAPPPVSGPDTTPPSTKEPVRTGSFFEELPVVSRSRPSTRGRYTPQPNMSQPASNLPMAPVAPPPSLPQQSSDPYSQFQLQPPARLDPYSNLSAPPPQPAPTTSRYSPQPPPPGTKPAPFPRYSPAPPQSACMTSSATYVSQSPTVQSSVNALPFQPRTSSPLAQHETAKSYPSPPRKRGSLPVTSIIPTSSVPQFGSDSQIVPPKRSMTQSPGRMMPLQSSVASNQNAYVRPASAHGSKSSIQAPLLQSAYAPAANNRPTQALDFVVPTDGQEHDPLERWKGAPIFKFGFGGTLLSTFPKHIPRYATGQMTPRIKPTLGDIKTCPISQILPHNEPLDKFPGPLKSKSKKKDVLTWLSTMISALEGAPSTTDGHVDPVHQHRREDGILLWKVVRVLVEHDGALRGSTAAEASLQSIFSPGSMAMNSQFEYPSTGDSVSGSLKSESASSLGIDVIHKSLVAGDRQKAVWDAVDHRLWGHAMLISSTLDKSVWKQVTQEFIRREVRSLGKNTESLAALYEIFAGNFEESIDELVPPSARAGLQMVSVHAGTGAPKDALEGLNKWRDTVNLILQNKIAQDHQALRALGRLLASYGRVEASHICSLVAGTAAGPIFGDARDPQASIVLLGADHWRNPTTFMVEREACLLTEVYEFATSVLAASPSPSLAHLQAFKLRHAMYLAEEGHKSEAQQYCEAIVSIVTSKSNVKSPYYHQRFFAELDELSHRLRQAPTDGSSSWISKPSMEKVSGSMWAKFNSFVSGDDNEVTSNGSGKGGDGDIGPFAKIAGTPPISRSPSVAEGHGSYFPSQPVAPSSSGSRYAPNSQYYAPYSSPEQSRGRRSLDAQRSPPQTAGRSYSQRRNSQDPSTPLEGNAYGSMPNHIYASPATIGSHITPPQASHAPLAPVEEIYSPQIQSPTSEMPAIQTLPDGFGINQTGYMPLAEQVTRDDETNLKTTTTEQSGYQPPTYEPPSFSTGYEPPSYSANVEDNEHSDEEKPKKKSFMDDDDDDFMARAAQLRASEKEKMDREAAEAFRKAAEADAKRPLATEKKGWFSGWFGKKESGGAVRADLGDENSFYFDKELNRWVNKKDPGSAATAAVTPPPPKSSAPSSQSVSTSQTPTTPNLTNGRPGPSAVPGGTLSAPPPGIAPLPTPPSSSLGPPSDSPRAIPRSVSAGAPTGPPSRPGTSLSNASSIDDLLGAPQARKGGTMKTRRKGRGYVDVMAK
What is the function of this protein?
Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules.  Also involved in autophagy (By similarity).
What are the official names of this protein?
COPII coat assembly protein SEC16, Protein transport protein SEC16.
What is the protein family that this protein belongs to?
Belongs to the SEC16 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KDSA_COXBN
Sequence: MLMQIADFEIGLNNPLFLIAGPCVIESEALVMDVAGELKSITQQLDMPFIFKASFDKANRSSHLSYRGPGIEKGLTILEKVKKTLEVPIITDVHEDTPLQEVAAVVDVLQTPAFLCRQSNFIRSVAACGKPVNIKKGQFLAPWEMKQVVAKAWATGNKKIMVCERGYSFGYNNLISDMRALAILRETACPVIFDATHSVQLPGGHGTSSGGQRKFVPVLARAATAAGIAGIFMETHPDPDRALSDGPNSWPLAKMQPLLETLKELDKVVKNAGFLEQSSE
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRB_MYCLE
Sequence: MAAQRKAQDEYGAASITILEGLEAVRKRPGMYVGSTGERGLHHLIWEVVDNSVDEAMAGYATQVDVRLFDDGSVEVADNGRGIPVAVHATGVPTVDVVMTQLHAGGKFGGKDSGYNVSGGLHGVGVSVVNALSTRVEVDIKRDGYEWSQFYDKAVPGILKQGEATEATGTTIRFWADPDIFETTKYDFGTVARRIQEVAFLNKGLTINLVDERVKQDEVVDDVVSDTAEAPVAMTVEEKSTESSAPHKVRHRTFHYPGGLVDFVKHINRTKTPIQQSIIDFDGKGAGHEVEVAMQWNGGYSESVHTFANTINTHEGGTHEEGFRSALTSVVNKYAKDKKLLKDKDPNLTGDDIREGLAAVISVKVSEPQFEGQTKTKLGNTEVKSFVQRVCNEQLIHWFEANPVDAKAVVNKAISSAQARIAARKARELVRRKSATDLGGLPGKLADCRSTDPRSSELYVVEGDSAGGSAKSGRDSMFQAILPLRGKIINVEKARIDRVLKNTEVQAIITALGTGIHDEFDISRLRYHKIVLMADADVDGQHISTLLLTLLFRFMRPLIEHGYVFLAQPPLYKLKWQRMDPEFAYSDSERDGLLETGLKLGKKINKEDGIQRYKGLGEMDAKELWETTMDPSVRVLRQVTLDDAAAADELFSILMGEDVDARRSFITRNAKDVRFLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state (PubMed:17325221).  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.