PharMolix/UniProtQA huggingface dataset:
Protein: MDH_CHLPN
Sequence: MAFKEVVRVAVTGGKGQIAYNFLFALAHGDVFGVDRGVDLRIYDVPGTERALSGVRMELDDGAYPLLHRLRVTTSLNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKRDAKIFVVGNPVNTNCWIAMKHAPRLHRKNFHAMLRLDQNRMHSMLAHRAEVPLEEVSRVVIWGNHSAKQVPDFTQARISGKPAAEVIGDRDWLENILVHSVQNRGSAVIEARGKSSAASASRALAEAARSIFCPKSDEWFSSGVCSDHNPYGIPEDLIFGFPCRMLPSGDYEIIPGLPWEPFIRNKIQISLDEIAQEKASVSSL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: V14K_WSSV
Sequence: VARGGKTKGRRG
What is the function of this protein?
Structural component of the virion.
What are the official names of this protein?
14.5 kDa structural polyprotein.
Protein: NB5R2_XENTR
Sequence: MEISTDSNMLVALAVIGVTVLLFLIKALGSQAKKAPLTLLDPNAKYPLPLIEKQEISHDTKKFRFGLPSQEHVLGLPVGQHVYLSAKINGSLVVRAYTPVSSDEVKGHVDLIVKVYYKNVHPKFPEGGKMSQHLDSLKIGETIDFRGPNGLLVYKEKGKFAIRPDKKSEPKLKVAKHVGMLAGGTGITPMLQLIRQITQDPNDNTKCSLIFANQTEDDILLRYELETVAKSHPEQFKLWYTLDRPPQGWKYGAGFVTADMIKEHLPPPSEDVVVLMCGPPPMIQFACQDNLTKLGYPEAGRFAY
What is the function of this protein?
NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis and drug metabolism.
What are the official names of this protein?
NADH-cytochrome b5 reductase 2, b5R.2.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PIG6_CLAP2
Sequence: MSKTPSYEDATACQAALFEWAESYDLKDWNRLSKCIAPTLQIDYRAVFGQFWEAMPADEFVGMISSPGFLGNPLIKTQHFVGMTRWTQTSEDSVTGRHQMRVAHQKYADAQMKEVVLKGHGHGGATTWFRKVDGDWKFAGIEPEIRWAEFDLDKIFAE
What is the function of this protein?
Scytalone dehydratase-like protein; part of the ergochrome gene cluster responsible for the typical purple-black color of the ergot sclerotia (PubMed:28955461).  The ergochrome gene cluster produces several ergot pigments including the yellow ergochrome secalonic acid and its derivatives, as well as the red anthraquinones endocrocin and clavorubin (PubMed:28955461).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) CPUR_05437 (By similarity).  The atrochrysone carboxyl ACP thioesterase CPUR_05436 then breaks the thioester bond and releases the atrochrysone carboxylic acid from CPUR_05437 (By similarity).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (By similarity).  The next step is performed by the anthrone oxygenase CPUR_05434 that catalyzes the oxidation of emodinanthrone to emodin (By similarity).  Emodin is further modified to yield monodictyphenone via several steps involving CPUR_05427, CPUR_05428, CPUR_05429 and CPUR_05430 (By similarity).  The short chain dehydrogenase/reductase CPUR_05418 then catalyzes the C-5 ketoreduction to give the xanthone skeleton of the monomeric units (PubMed:32105084).  Ergochromes formation requires further dimerization steps of different xanthone units, probably catalyzed by the cytochrome P450 monooxygenase CPUR_05419 (PubMed:28955461).  CPUR_05425, CPUR_05426 and CPUR_05431 are unique to Claviceps, thus it is likely that they are involved in further modification of xanthone units or in their dimerization (PubMed:28955461).  The yellow ergochromes and the red anthraquinone pigments endocrocin and clavorubin are products from the same PKS derived precursors and the latter are likely shunt products in the pathway of xanthone biosynthesis (PubMed:28955461).  It is proposed that atrochrysone carboxylic acid released from the PKS CPUR_05437 can also be converted to endocrocin anthrone which is further oxidized into endocrocin by CPUR_05435 (By similarity).  Endocrocin could be then modified to clavorubin, possibly by CPUR_05423 and CPUR_05431 (PubMed:28955461).  Clavorubin is the principal anthraquinone metabolite produced by the cluster with a much higher yield compared to endocrocin (PubMed:28955461).
What are the official names of this protein?
Scytalone dehydratase-like protein CPUR_05428, Ergochrome gene cluster protein CPUR_05428.
What is the protein family that this protein belongs to?
Belongs to the scytalone dehydratase family.
Protein: YIHI_HAEIG
Sequence: MARKKKTRRITDIMPIRKADKKIDITKARSGKKLTRYELDAKAREDKKKRKHKGLASGSRHSAVEEKANKLQNEIKDPKIGSKKKIPLVVEFVNKPEKGQVIPVIKQVKKQDPMKELENLENNEILNELLDALDAGKTISKSDQQFVDECLDRISELMEELGIEDEDESEDDLYRTFERMDINQFR
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: RL28_ALIFM
Sequence: MSRVCQVTGKRPAVGNNRSHAKNATKRRFLPNLQTHRFWVESEKRFVKLRLTAKGMRIIDKKGIETVLADMRARGENV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NNRD1_PUCGT
Sequence: MVLTTRHHLDGFRSIQVMLGALEHPLDVMKASKGRSCSENDHRMYRFSKNLPRGVCSPLTTGPHPTTHLEPTMHQPHRSLLRKAFQMIPPLDGSLHKGQAGRIGIVGGSKDYTGAPFYSGYASLRLGSDLSHVICEPSASTVIKTYSPDLMVHSYLSSPKEPEAYASHQNLFEQLLDRLHVLVVGPGLGRDTEMQDWAEWTLKTAIKKKLHLVLDADALWLLVKKPDLLRGYPNAILTPNHVEFQRLLKACSIEPRENDDDGLLAMELSKALGGCSILQKGSIDLVAREGSEVAKVSCEGSPKRCGGQGDILSGLVGTWCAWTKLYFERQSQDEKPKSHELPISSEEAWIIAAVLGSEITRTCSRLAYHKLGRSMQSSDMLGYIGEAFELVMHGHTKD
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase 1, ATP-dependent NAD(P)HX dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_MYCUA
Sequence: MTNDPAEISSRKRRHIDVCLNDEVNYVGVTTGLERYRLPFNALTQTSLADIDLSAEFFGAPLRAPVLIGAMTGGAELSAMINRNLATAAQRLGIGMMLGSQRIMLDDARGQRAASSFAVREVAPDVLLIGNIGLAQLTKAAVPAVAAALRRVGANALAVHANSLQEAMQHGGDTDFSGSLGRLRDAADLLDYPVLLKEVGHGIGAAAVAQLLRLPGGLPVSGIDVAGAGGTSWSRVEQLVRYGELRYPELADWGIPTAEAIVEVRQALPAVPLVASGGIRTGMDAAKSIALGADVVAIARPLLAPAIESATAVQDWLQLFLDELRVCLHCCGAPDLTSLRDIGVTAIR
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP2M_YEAST
Sequence: MISGVLVYSSRGELVLNKFFKNSLKRSISDIFRVQVINNLDVRSPVLTLGSTTFHHIRSRHGDNLWLVTITRSNANSAAIWEFLYKLDAVMNAYRLDREEALKEEFMIVHEMLDIMLGGNGIPIDTELNSVIAQMSVKPVRNMGGLLDSPDGNDVLSSSSSPTSSAGELHFPKFLTKRSSSFLGQGDSTSDFYDNNKITWRPKGIIHKKDEVFLYVNERINILVSRDGSILKSYVDGTIDITTHLSGTPICRFGLNDSLGMQSEDEKKWLAQQQRHSGSDFGNKNFIPKAAAGSVLLEDCKFHECVSLDKFNRNHIIEFVPPDGSMELMKYHVRDNINLPFKVTPIVTHSTRDNEIDYRITLKSLFPGKLSAKDVVLHIPVPPSTVDCKISVSNGHCKFVPEENAMIWRFNKYNGLTENTLSAVTVSTSDTTQLNLQQWTRPPISLEFEVMMFSNSGLVVRYFTISGKDSKHRAVKWIKYISKAGSYEVRY
What is the function of this protein?
Component of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
What are the official names of this protein?
AP-2 complex subunit mu, Adaptin medium chain APM4, Clathrin assembly protein complex 2 mu medium chain, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP50, Mu2-adaptin, Plasma membrane adaptor AP-2 50 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Cytoplasmic vesicle, clathrin-coated vesicle membrane.
Protein: RL27_PSYCK
Sequence: MAHKKAAGSSRNGRDSNPKMLGVKIFGGQAIVAGNIIVRQRGTEFHAGEGVGMGRDHTLFALNDGVVKFATKGKFNRRYVMVESA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RK14_CHAGL
Sequence: MIQPQSYLNVADNSGARKIMCIRILGGSNKKYGHIGDTIIGVVKEAIPNMTLKKSEVVRAVIVRTCKELKRKNGTILRFDENAAVIINQEGNPRGTRIFGPVARELREANFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KHSE_ECO45
Sequence: MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMG10_METTH
Sequence: MEMMVLLSQEHPELPSAELRSVLMSEGIDFSVIESGSGYEVIDAPRSTWKILKKRLAYAHEISEVIGYAAADDLDDAAEEIDWSKYVRESFAVRIRKLCGDVDSRTLERTIGAIIKEDTGLKVDLEKPWTLIRPVLINDRFILTRRLAVISKEHFNQARPHKRPFFYPGSMSPKLARCMVNLSGVKAGDRILDPFCGTGGILIEAGLMGVRVVGADIDWRMVEGTRENLQHYGITDFEVIRSDARDLRLDEKVDAIVTDPPYGISASTAGEKSEKLYREFLDSAHSNLAEGGMICMAAPHYLDLESLIDERFSIRERYSMRMHRSLTRVIRVIERV
What is the function of this protein?
Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs.  Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G) (By similarity).
What are the official names of this protein?
tRNA (guanine(10)-N2)-dimethyltransferase, tRNA:G10 dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Trm-G10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_MARMS
Sequence: MRPSGREADQLRPLKITRNFTKHAEGSVLIECGDTKVICTATVVSGVPRFLKGKGQGWITAEYGMLPRSTHSRMDREAARGKQGGRTVEIQRLIGRSLRAAVDLKKLGENTITIDCDVIQADGGTRTASITGGFVALADAMRVLVENKKVKENPIVSQIAAISVGVYKGVPVLDLDYPEDSNAETDMNVIMNDKGGFIEIQGTAEGEAFSDEHMMGMLAVARKGIAEIMEAQRAALFDK
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: MOBA_YERPY
Sequence: MQPNITGVILAGGRSSRMGGNDKGLIPLNGKPLFQYVIDRFKPQVSDLLINANRNQGLYKESGIPVIDDIITGFVGPLAGMHAGLSYASTEWVVFAPCDVPALPSDLVSQLWQGKKQALAAYANDDERAHPTFALMHISLKTQLADYLIRGDRKLMLFLDSINAQRVKFSGKADLFSNLNTPADCDLWEQKRRGQ
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_BURCM
Sequence: MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRVGERPYLVVDTGGFEPVAKDGILHQMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVATDFYELGLGDPRAISAAHGDGVTDMINEALEVAYAGQPEEADEDDPSRGIKIAIVGRPNVGKSTLVNALIGEDRVIAFDMPGTTRDSIYVDFERNGKKYTLIDTAGLRRRGKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVIGVNKWDGLDDHARDRAKADLTRKLKFLDFAKSHYISAAKKTGIGALMRSVDDAYAAAMAKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPLIVIHGNALDAVTETYKRYLENRFRETFSLTGTPLRIEFRSSNNPYADKG
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: MEP4_ARTBC
Sequence: MHGLLLAGLLALPLNVLAHPTESHSSGVSRRAIDITSYRLPQISKYTKSDAVPKQDGESFTTSSTGDDNVSSGDYVTTATNWLKKTLPKATYRLVNDHYIGDSGIGHVHFRQTAHGIDIDNTDFNVNIGRDGKVFSFGNSFYDGEIPKANPMVKRDFSDPVNALHGAIQTLNLPVTAKPENVKAKPVEGKENFKFEGTSGALSDPKAQLVYLQKDGGLVLSWKVETDVGDNWLLTYVDANKNDQVHSVVDYVSAAEYQVYPWGINDPTEGNRTSIHLPWLKTLSTDWHIDGKGWYPTTRGNNAIAQENPTGHPEYENNYRPKSPLFIFKYPYSLAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQINNWNKGGVGGDFAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASTPERDGCFEAGIVIHEYTHGVSNRLTGGPENSRCLAALESGGMGEGWSDFFATAIRLKPGDTRATDYTMGEWASNRPNGIRKYRYSTSLTTNPHMYVDADGLTSVHAIGTIWASMLYELLWNLIDKHGKGDVTKIRPVLKNGVPTDGRHLAMKIVLDGMALQPCLPNFVQARDAILDADKNLTQGSNKCEIWKAFAKRGLGVGAAFNQTKRTGSNELPAGC
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Probable extracellular metalloproteinase 4, Fungalysin MEP4.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMM_CHLTB
Sequence: MTRDVSQLFGTDGVRGRANFEPMTVETSVLLGKAIAGVLLEKHAGKHRVVVGKDTRLSGYMFENALIAGLTSMGIETLMLGPIPTPGVAFITRAYRADAGIMISASHNPYRDNGIKIFSSDGFKIGQAVEERIEAMVASKDFGKLPDDHAVGKNKRVKDATGRYIEYAKATFPKGRTLKGLRIVLDCAHGATYRVAPSVFEELDAEVICYGCEPSGCNINAGCGALWPSTIQKAVIEHKADVGIALDGDGDRLIMVDEKGHIVDGDMLLSICASDLKRRQALPDNRVVATVMTNFGVLRYLESLGIQVTISPVGDRHVLQHMLENQAVLGGEQSGHMIFLDYNTTGDGIVSALQVLRIMIESESTLSDLTACIVKSPQALINVPVTKKVPLESLANVQGVLKEVKEVLGDSGRILLRYSGTENICRVMVEGTKKHQVDSLAKTIVDVVEAEIGAGISE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SYM_PSEPF
Sequence: MSEPRKILVTSALPYANGSIHLGHMLEYIQTDMWVRFQKHRGNQCIYVCADDAHGSAIMLRAEKEGITPEQLIANVQAEHSADFAEFLVDFDNFHSTHAEENRELSSQIYLKLRDAGHIAQRSITQYFDPEKKMFLADRFIKGTCPKCGTEDQYGDNCEKCGATYAPTDLKDPKSAISGATPVLKDSQHFFFKLPDFQEMLQAWTRSGTLQDAVANKIAEWLDAGLQQWDISRDAPYFGFEIPGEPGKYFYVWLDAPIGYMASFKNLCNRTPELDFDAFWGKDSTAELYHFIGKDIVNFHALFWPAMLEGAGFRKPTGINVHGYLTVNGQKMSKSRGTFIKARTYLDHLSPEYLRYYYAAKLGRGVDDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIQKGNAGLLVDTNAAPELTEAFLAAAPSIADAYEARDFARAMRETMALADRANAWIADKAPWSLNKQEGKQDEVQAVCATAINLFRQLVIFLKPVLPVLAADAEAFLNVAPLTWNDHTTLLANHQLNEFKPLMTRIDPVKVQAMTDASKEDLTASQTDTGAAAPAGNGELAKDPLSPEIDFDTFAAVDLRVALIVKAEHVEGADKLLRLTLDIGDEQRNVFSGIKSAYPDPSKLDGRLTMMIANLKPRKMKFGISEGMVMAAGPGGEEIYLLSPDSGAKPGQRIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_BUCA5
Sequence: MIKIYAPASIGNVGVGFDILGAAIIPINGSLLGDFVTVKLSNKFNLVNKGIFSNKLPKNTEQNIVWKCWLKFCNTIKRNIPVSIILEKNMPIGSGLGSSACSIVATLVAMNEFCDKPLNSKELLLLMGEVEGEISGSIHYDNVAPCYLGGLQLILEDSKIISQTIPNFKNWFWIVAWPGTKVPTAEARDILPKKYKKETCIKNSRYLAGFIHASYSQQPHLAARLMQDFIAEPYRIKLLPNYLYVKEKIKKIGAISSGISGSGPTIFSISDNINTAQKISAWLTENYLQNTTGFVHICFLDSKGVRKIG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_HYPNA
Sequence: MKLISCNANRPLSDAIADYLDMRLTRSEVKTFADQEIFVRIDENVRGEDVFVIQSTSYPANDNLMQLLIMMDALRRASARRITAVIPYFGYARQDRKTDGRTPISAKLVANLISTAGADRVLTVDLHAGQIQGFFDIPTDNLFGGPVMVDDIKERYGKEKIIVVSPDVGGVVRARSLAKRLDDADLAIVDKRRPEAGKSEVMNIIGDVRGARCIMLDDMCDSGGTLANAAAALKEHGASSVSAYVTHGVLSGSAVERIEKSVLDELVMTDTIQPSEHALKSKNIRVLPISPLLGEAIRRIANEESVSKLFDR
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_LISMF
Sequence: MKLLEEFIQEKGTVLPGNVLKVDAFLNHQIDPVLMQAMGNEFAKRFQDLGITKIVTIESSGIAPAVFAGLALSVPVVFARKKKSVTLTDNLFTSTVYSYTKKESNDISVSKQFLTADDTILVIDDFLANGQAALGLLEIAEHAGAKVAGIGIVIEKSFQQGRELLNKTGIPVYSLARIASLENEEILFLEEE
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_PSEA7
Sequence: MTENALLLLNLGSPDSTRVEDVRRYLDQFLMDPYVVDLPWPLRRLLVSLILVKRPAESAHAYSSIWWDEGSPLIVLSRRLQEAIKPHWPHGPVELAMRYGQPAIEKVLLDLARRGIRRVTLAPLYPQFADSTTTTAEQEVRRVIAAHRLELEVSTLPPFYDQPVYLDALVESVHPYLQQPHDHLLLSFHGLPERHIRKLVKDPAHDLLAESSRNVSPEALALCYRSQCLRTAEAFAERAGLEQGRWSVSFQSRLGRAKWIEPYTDAKLDELVQRGVKRLLVMCPAFVADCIETLEEIGMRGREQFISAGGEDLVLIPCLNDHPAWVGALADMSGRLARPL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TL16_ARATH
Sequence: MAKSLLCSSTLNPFFSTTLSSSKKNQIAYSGNSKNQTSSSLLWKRRELSLGFMSSLVAIGLVSNDRRRHDANAAILEADDDEELLEKVKQDRKKRIERQAVLNSAVKEKGYLQDLVYKLSKVGQAIENNDLPAAGLVLGKGIDTEWVKTVNLAFTKLSTSPEENTEVEAFNSSLASLITSVNKNDIESSKLAFVSSAGAFEKWTTLTGLLEQLKGL
What are the official names of this protein?
Thylakoid lumenal 16.5 kDa protein, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: CUC12_CONCL
Sequence: DLITNSYTRGKPRHVTSWRNLRTDVCKKSPGKCIHNGCFCEQDKPQGNCCDSGGCTVKWWCPGTKGD
What are the official names of this protein?
Conotoxin Cal12.1p2.
What are the subcellular locations of this protein?
Secreted.
Protein: PEX26_HUMAN
Sequence: MKSDSSTSAAPLRGLGGPLRSSEPVRAVPARAPAVDLLEEAADLLVVHLDFRAALETCERAWQSLANHAVAEEPAGTSLEVKCSLCVVGIQALAEMDRWQEVLSWVLQYYQVPEKLPPKVLELCILLYSKMQEPGAVLDVVGAWLQDPANQNLPEYGALAEFHVQRVLLPLGCLSEAEELVVGSAAFGEERRLDVLQAIHTARQQQKQEHSGSEEAQKPNLEGSVSHKFLSLPMLVRQLWDSAVSHFFSLPFKKSLLAALILCLLVVRFDPASPSSLHFLYKLAQLFRWIRKAAFSRLYQLRIRD
What is the function of this protein?
Peroxisomal docking factor that anchors PEX1 and PEX6 to peroxisome membranes (PubMed:12717447, PubMed:12851857, PubMed:16854980, PubMed:21362118, PubMed:16763195, PubMed:16257970).  PEX26 is therefore required for the formation of the PEX1-PEX6 AAA ATPase complex, a complex that mediates the extraction of the PEX5 receptor from peroxisomal membrane (PubMed:12717447, PubMed:12851857, PubMed:16854980, PubMed:21362118, PubMed:16763195, PubMed:16257970).
What are the official names of this protein?
Peroxisome assembly protein 26, Peroxin-26.
What is the protein family that this protein belongs to?
Belongs to the peroxin-26 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass type II membrane protein.
Protein: LPXD_SACD2
Sequence: MSNCKFTLAQLADHLDAQMVGDANYTVECIAPLESAGKNALSFLANSKYEKALATSQAGIMLLAQDSAEKFNGNKLIVKNPYLCYAKLSELFNFRLAKKQGVHPSATVDADATVAADAYIGPNCVIEAGAVIGGGTQLGAGCFVGADTKLGNNCLLHANVTLYAGVELGNKVLIHSGTVIGSDGFGFAPSAEGWVKIHQLGGVVIGNNVEIGSNTSIDRGALDDTIIEDGVIIDNLVHIAHNVKIGAGSAIAGCVGIAGSAVIGKNCTVAGMVAINGHITIADNTHFHGGTIVTKGVKESGAYASAPPMQEVSKWRRNAVRYGQLDEWVEKIKALQKAQKD
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: UBE11_WHEAT
Sequence: MLPRKREIVAGEVEDLQKKTRAGEGEVTREEGDAAMAGRGNEIDEDLHSRQLAVYGRETMKRLFGSNVLVSGLQGLGAEIAKNLVLAGVKSVTLHDDGNVELWDLSSNFFLSENDVGQNRAQACVQKLQELNNAVLVSALTGDLTKEHLSKFQAVVFTDISLDKAIEFDDYCHSQQPPIAFIKSEVRGLFGSVFCDFGPEFTVLDVDGEEPHTGIVASISNDNPALVSCVDDERLEFQDGDLVVFSEVHGMTELNDGKPRKVKNARPYSFFLEEDTSSFGAYVRGGIVTQVKPPKVIKFKPLKEAMSEPGEFLMSDFSKFERPPLLHLAFQALDKFRTELSRFPVAGSTDDVQRVIEYAISINDTLGDRKLEEIDKKLLHHFASGSRAVLNPMAAMFGGIVGQEVVKACSGKFHPLYQFFYFDSVESLPVDPLEPGDLKPKNSRYDAQISVFGSKLQNKLEEAKIFMVGSGALGCEFLKNLALMGISCSQNGNLTLTDDDVIEKSNLSRQFLFRDWNIGQPKSTVAATAAMVINPKLHVEALQNRASPETENVFNDAFWENLDAVVNALDNVTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPTEVNAFLSNPTTYISAARTAGDAQARDQLERVIECLDRDKCETFQDSITWARLKFEDYFSNRVKQLTFTFPEDSMTSSGAPFWSAPKRFPRPVEFSSSDQSQLSFILAAAILRAETFGIPIPEWAKTPNKLAAEAVDKVIVPDFQPKQGVKIVTHEKATSLSSASVDDAAVIEELIAKLEEVSKTLPSGFHMNPIQFEKDDDTNFHMDVIAGFANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKALAGGHKVEDYRNTFANLAIPLFSIAEPVPPKTIKHQELSWTVWDRWTVTGNITLRELLEWLKEKGLNAYSISCGTSLLYNSMFPRHKERLDRKVVDVAREVAKMEVPSYRRHLDVVVACEDDDDNDVDIPLVSVYFR
What is the function of this protein?
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP.
What are the official names of this protein?
Ubiquitin-activating enzyme E1 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.