PharMolix/UniProtQA huggingface dataset:
Protein: PVK1_GYNCS
Sequence: GSTGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, GynCa-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BAFL_MOUSE
Sequence: MDDMSPRLRAFLSEPIGEKDVAWVDGISRELAINLVTKGFNKAYVLLGQFLLMHKNEAEFQRWIICCCGATECEARQSSTCLKEWCSCFL
What is the function of this protein?
May play a role in BANF1 regulation and influence tissue-specific roles of BANF1.
What are the official names of this protein?
Barrier-to-autointegration factor-like protein, BAF-L, Barrier-to-autointegration factor 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RECF_SHESM
Sequence: MSLIRLNIDSFRNIQLAQLSPSSGINLIYGQNGSGKTSILEAIYFLGMGRSFRSHLSQRVINNEQDKLTLFATLNLPRGDSKIGLRRFRSGETEVKIDGEKVKRLSTLAETLPIQVITPESFSLLFEGPKSRRQFIDWGAFHSDPQFYAAWVNVRRVLKQRNQLLRNNSSYDQIQYWDREFVRYTEQVTEIRNRYVDSLNELLKGIIGEFLPQVDVKVSFTRGWDSKTDFAQLLESQYPRDLATGHTVSGPHKADLRLRVGSLPAQDALSRGQLKLLVCALRIAQGKLLKQQIDKHSIYLVDDLPSELDAQHRQLLLKQLVDTGAQVFVTAIEPAAIVDSLHTPPSRMFHVEQGRVTVIE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EGL43_CAEEL
Sequence: MSIDTDFLTSVEVKEDELHGNVLIAVTQIALGRTIGVIDKATPNDSNALLILNLIKEADDGEDANICMRQEDRKTFLQTSKIINIGERLLLQRLSEEECDEEDQDDLENLILLKDEDRPDSTQSCTKSSSEDSNLNGFEEYIREHGELVPGQTPPDGSHKCGVCPKSFSSASGLKQHSHIHCSLKPFRCHLCPKSYTQFSNLCRHRRVHSDGWTCPTCQSQMPSQAALTKHRPVCEMTALYKPLMAQLAGLSGAGGLGSVPYWPHILQMATQAPHFPLAFLAANPEAYKLMQQTTCASPDAECSSGHASESSPTTTEPVDLTATPKPPSTSEMETTSKSDDGEDRDSIGDSGNDDDDDSEAGVLDESSTTTSTKKRPTSHTISDILAAPQLGAQALNSTFLGMLQRSLNYNPAVPSPHSFLRAMSGAKASSSPSSSSGSGKDRYTCKFCQKVFPRSANLTRHLRTHTGEQPYKCQYCERSFSISSNLQRHVRNIHNKPNTSLTPHNHHRQRSLHNSTSTSTTTTTVHHPLLHLPGTSVPVPKV
What is the function of this protein?
Dispensable for anchor cell (AC) invasion and for preventing AC proliferation.
What are the official names of this protein?
Zinc finger protein egl-43, Egg-laying defective protein 43.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y704_HALHL
Sequence: MHYQLRRRGTKMTELRGRLRAAGDRLRALPTHPGVGEARGFGEYLIQRIQQDQCAKSAGMLAYVTLLAIVPLMTIGFSVLAAFPVFEGVTDRLREAMVDYLVPAASDAIDEHLENFMGRAAELTAVGIAGLTVTALLLLNTIERVLNEIWRVERPRPTLQRFMVYWTVLTMGPLLLGVSVASTSYMGTVNLGPLEPPSDLIAQLLNLAPFVVQAIVFSLIYSLVPHRSVPVLHAVIGGVVASGLFELAKGGFAAFIARAPTYEVVYGALAALPIFLVWLYISWLVILIGAEVTQALRGYRWRTGGDLARNRWALVLAVHILGHLYQAQRRGAGVTFAELLEQEPDAGEPALAEALETLRRHHVIERSADGAWLLARDTSTFTLAELHRMLAYPLPPAAGLETGAPWDRRLAERLRRVEERWEQSFDLSLSDLLEPTAEEAGAGRSARAEVA
What are the official names of this protein?
UPF0761 membrane protein Hhal_0704.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MAP1_BUCAI
Sequence: MSCIIKTESEIKKMRISGKLAAEVLEMIKEHLQPKISTEDINQICHDYIVYKKKAISACLGYHGFPKSICISINDVVCHGIPSKNQVFKEGDIVNIDIAIIKDGYHGDTSKMFYIGKTSILSKRLCQVARESLYLSLKLVKPGIPLYKIGEIIQNYVESNNFSVVKEYCGHGIGRNFHEEPHVLHYKNKKNNIILKKGMIFTIEPMINSGNPEVKCMKDGWTVKTKDRSLSAQYEHTVLVTEYGCDILTWQKDEDISQKLVNIN
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: YD249_YEAST
Sequence: MGYILTGYSSRHDKRKKHALPLHRYASSSINLQHHVHLLETRVSSKRPISEDQRTIRLPAKKLRHHQKLTLQDLPVEIIQHIFVFTKGEPSMVTLNRFFYSCLKPSFSLLSKIMWEKYLFDPLEFGVSNIKAYSRNIVIPTLFEHETFFRLLLDHHPILLKNISHFLPRKHYQDMQNGDFDTSKELDLCSMNTEDTSKEDFPKNFYNNMHIFLTRRECVKSLGNHFTLKNPYDVISPFIEWFFQGIDMQGTDLSPKFTFVSLFESIDLILYVSGSTVQKLASIEPLTTVIFLLYFTYADSLGSLNFEFFLQNRSRLQLIEKFILKYYYNPSLTENELLSDSTIWDLLRRVSDLKLIDLVVKCGGRPQYGVMFA
What are the official names of this protein?
Uncharacterized protein YDR249C.
Protein: YBEY_LACH4
Sequence: MDPIDVTYHDEVGFLDDKNRNWQDWIMKLLLLAKKEIGKDNNLEMSINFVDEDRSHEINLKYRDKDRPTDVISFAIEDGEDAIDLSVFEDDPDFQEDIGDLFMCPSVIKRHSKEYGTGFDREFGYTVVHGFLHLNGYDHIKPDEAKEMFGIQGKVLEECGLPLYPDQLDEGRGK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP3_SAIBB
Sequence: MENTENSVDSKSIKNSEPKIIHGSKSVDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMASRSGTDVDAANLRETFMNLKYEVRNKNDLTREEIVELMRNVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITSFFRGDCCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSRDGSWFIQSLCAMLKQYAHKLEFMHILTRVNRKVATEFESSSFDATFHAKKQIPCIVSMLTKELYFYQ
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.  At the onset of apoptosis, it proteolytically cleaves poly(ADP-ribose) polymerase PARP1 at a '216-Asp-|-Gly-217' bond.  Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain.  Cleaves and activates caspase-6, -7 and -9.  Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).  Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes (By similarity).  Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress.  Acts as an inhibitor of type I interferon production during virus-induced apoptosis by mediating cleavage of antiviral proteins CGAS, IRF3 and MAVS, thereby preventing cytokine overproduction.  Also involved in pyroptosis by mediating cleavage and activation of gasdermin-E (GSDME) (By similarity).  Cleaves XRCC4 and phospholipid scramblase proteins XKR4, XKR8 and XKR9, leading to promote phosphatidylserine exposure on apoptotic cell surface (By similarity).
What are the official names of this protein?
Caspase-3, CASP-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPH2_NEMVE
Sequence: MEVETTAKSYDVPASAFSESAVIDTHLDVPSTKTESIERMVEVYEIERSVQVITSSGFNKVALQFPDSLLADSASVARLIEQRASCKAFILADTSYGRHPPLPANKTFLKLYNVRICFKLLAFLHFSSCCVDEIAAEHADAELIIHYGQACLSQTKRLPVLYVFGKNPINVIECSQHFRQLYPDTGIRVLVFYDVVYNHCIGALDEALSPLYPNMTISTIAPEGLPSEPTSQQSSRNPQASDVEGMEVNQCNRRFGRDFTLAANSSISDYQIFYIGEQSLTLRNLMMTYNKCQFSTYDPITNESRRETLNVNKALMKRYHMIQRAKDAQIVGIVVGTLGVADYLKIIERLKKVLAIAGKKSYVFVMGKLNVAKLANFLEIDVFVLVSCPENSLIDSKEFYKPVVTPYEMEIACLRTQEWTGDYVTDFHELLPGKSINTFWTDDNDDSPYISLITGKMQHNYKSSAKEAGETSTSLVQRNQETTLATQQPLTAEFLASRSWQGLQQNLGDTPVTTAVEGRRGIAAGYTDEGE
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the dph1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
Protein: AMPA_BACLD
Sequence: MFYAFKDFEKKETLLIGLFKKSRLYGKAEEIDRLLNGQLSQLLKDGDVSSKKAKVSKIFTPSLQGVKRIYIVGLGREAEFTFEDAKQCFAEAVQLIHKDRKQELTVMLDSFVSEEVPAADAAHALAESCMLSCYEVQDYKHRSNVPDQCLQSVYVLTDHDLKEIQASLHVGQVYGNATNSARTLVNMPGNMLTAADLASYAAELAAKYEFECEILEKAEMEELGMGGLLAVNQGSEEPPKMIVLKYQGKETWDDVIGLVGKGITFDTGGYSIKTKSGIVGMKSDMGGAASVLGAMEAIGELRPEQNVLAVIPSTDNMISGSAMKPDDVIVSLSGKTIEILNTDAEGRLALADGLTYAKHHGASVLIDVATLTGGVVVALGTETTGAMTNHDPLYQQVRQAAEEAGEAIWQLPITEKDKKRVKNSQMADLNNSPGREGHAIMAGTFLGEFAEQTPWVHLDIAGTATTAQNSCFGPKGGTGVMVRTLVTFVERFSGNL
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REP11_ECOLX
Sequence: MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNTLSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVELPFVEFAKLCGIPSSQSSRSLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSAYYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPAPISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPRLKAPNDESKENPLPPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR
What is the function of this protein?
This protein is essential for plasmid replication; it is involved in copy control functions.  In vitro, binds to the DNA repeat units, BCDD'D'', EFG and HIJ (By similarity).
What are the official names of this protein?
RepFIB replication protein A.
What is the protein family that this protein belongs to?
Belongs to the initiator RepB protein family.
Protein: RAN4_ARATH
Sequence: MALPNQQNVDLPTFKLLIVGDGGTGKTTFLKRHLTGEFEHNTEPTLGVDIYPLDFFTNRGKIRFECWDTAGQEKYSGLKDAYYIHGQCAIIMFDVTARHTYMNIDRWYRDLRRVCKNIPIVLCGNKVDVPSRQIKPKHVSYHRKKCLQYYEMSAKNNCNFEKPFLYLARRIAGDAKLSFVESPEAQIDNLDVESLQLLTVEAGTQPLLMTRISFEFNTLSIE
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein Ran-4, Ras-related nuclear protein 4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMG_XANC5
Sequence: MNDAALAPDVSAALERGLQAQSLDAAFAAPLLRYLALLVRWNKTYNLTAVRDPREMVTRHLLDSLAMQPYIASGTLADLGTGPGLPGIPLAITRPQLQVTLVESNGKKARFMREALRHLELGNARVAESRAEALDEPAAYDHLTARALDTLAGIIAVGGHLLRPGGSLLAMKGVYPHEEIAALPAGWTVGEVHPLQVPGLEGERHLVVVRKG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMO3_RABIT
Sequence: MGKKVAIIGAGISGLASIRSCLEEGLEPTCFEMSDDIGGLWKFSDHAEEGRASIYQSVFTNSSKEMMCFPDFPFPDDFPNFMHNSKLQEYITTFAREKNLLKYIQFKTLVSSIKKHPDFSVTGQWYVSTERNGKKETAVFDAVMICSGHHVYPNLPKDSFPGLKHFKGKSFHSREYKEPGIFKGKRVLVIGLGNSGCDIATELSHTAEQVVISSRSGSWVMSRVWDDGYPWDMLYVTRFQTFLKNNLPTAISDWWYVKQMNAKFKHENYSLMPLNGTLRKEPVFNDDLPARILCGTVSIKPNVKEFTETSAIFEDGTVFEAIDSVIFATGYGYAYPFLDDSIIKSENNKVTLFKGIFPPQLEKPTMAVIGLVQSLGAAIPTTDLQARWAAQVIKGTCTLPPVKDMMNDIHEKMGTKLKWFGKSETIQTDYINYMDELASFIGVKLNIPWLFLTDPRLALEVFFGPCSPYQFRLVGPGKWPGARQAILTQWDRSLKPMKTRAVGHLQKPALFSPWLKLLAIAVLLIAAVLVF
What is the function of this protein?
Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds.  Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite.  TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine.  By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.
What are the official names of this protein?
Flavin-containing monooxygenase 3, Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline oxidase 3, FMO 1D1, FMO II, FMO form 2, Hepatic flavin-containing monooxygenase 3, FMO 3, Trimethylamine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: GCSPA_LISMF
Sequence: MAKHRYLPMTEQDEKEMLDVIGVKSIDDLFQDIPEKIRFKRDYDLKPAKSEPALLRELSKLASKNANTTEYASFLGAGVYSHYIPTVVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMIAELTGMDLANSSMYDGGTALAEAAMLASGHTKRKKILISGAVHPESSNVLKTYATGQHIEVEVIPELDGKTDIEALKKALSDDIAGFVVQYPNFYGQVEPLAELEKLVHENNSLLLVSSNPLSLGLLTPPGEFGADIVVGDSQVFGIPESFGGPHCGFFAVTNKLMRKVPGRLVGETVDENGKRGYVLTLQAREQHIRRDKATSNICSNQALNALASSVAMATLGKTGLVEMAKQNLDKSHYAKQKFREKGFEVLFSDGFFNEFVVKLSKPIKEVNESLLDEGIIGGYDLGFYEEKYENHMLVAVTEMRTKEEIDAFVASLEGAK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: HSLV_STAA8
Sequence: MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYESLKVAADICVFTNDNIVVETL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_RHILO
Sequence: MSGEYDDLKRRMDGAIAAFKHDLASLRTGRASSNLLDAIQVQAYGTTMPINQVANVTVPEPRMISVSIWDKSMVGAVDRAIRESNLGFNPIVDGTNLRIPLPELNEQRRKELVKISHGYAENARVAARHVRRDGMDFLKKAEKDGVISEDDQRKRSDQVQKLTDETISTIDHLLSDKEAEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMF23_MARPO
Sequence: MQAQVMKTKCNVFYGIIKNRTPRVVIPISKINYRQIPGIFSKYSSRGFAIGVTSDISPVLLGKATDFSLFLSFGNTETVFSLRLRSTFSNLPRLPIMTF
What are the official names of this protein?
Uncharacterized mitochondrial protein ymf23, ORF99.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYDND_CAMJ8
Sequence: MRSHYNTDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPNDSKEAHEIASNARNEFVLIAEGTIRPRGEGLVNPKLKTGEIEVVVSKLTIENESAVPPFAIADESVNEELRLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFLEVETPILTKATPEGARDYLVPSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQPEFTQIDVEMSFCEQKDVINVAETFLKDIFKACGKEIQTPFRQMQYKDAMENYGSDKPDLRFDLKFIDVIDIFAKSNNEIFANIAKDTKKNRIKAIRVPKGDTIFSKRQMQRFEEFVRKFGAQGLAFIQVKEDGLKGPLCKFFSEEDLNELSKRCELEVGDVVFFGAGAKKTVLDYMGRFRIFLANELNLIDPNALEFLWVVDFPMFEQNDDGSYSAMHHPFTMPKNIDETDLEEISSIAYDVVLNGVELGGGSIRIHKNDIQQKVFKLLNIDEEQQKEKFGFLLDALSFGAPPHGGIAIGLDRLIMLVTGANSIREVIAFPKTQRAQCLMTDAPSPASNEAMRELGIKLRENIK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMC_SHIBS
Sequence: MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRAHTQQFHHWQVLSRQMGDNARFSLVATVDDVADCDTLIYYWPKNKPEAQFQLMNLLSLLPVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWGEYSVDGLTVKTLPSVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANCVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRAIMTRQAKKG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB_STRPU
Sequence: REEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFDEEEEGDEEAA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NTPP_LEIXX
Sequence: MRLYLASTSPARLALLRAAGIEPVVVPSQVDEPAAVAAAEAEHGPLSPDAMVQLLARLKAEAVRGALDGEPIDGLVFGGDSAFAIDGALHGKPHRPEIARERWRAQRGRTGRLHSGHWLIDHRGGVENAAVGATAVAAVSFADVTDAEIDAYIASGEPLEVAGAFTIDSLGGPFIRRVEGDPSTVVGLSLSTLRDLVRQLRIEWTELWNRAGVSL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_SALA4
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGENEQVDTVSGVNAVSSIGDDVVDLIAHVDLITTAVGPVVLERIAPAIAKGLVKRKAQGVDAPLNIIACENMVRGTTQLKGHVMNALADGDKAWVEQHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGTLPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDESIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHVNLVKGIAAAMHFRSDEDPQAQELAALITEKGPQAALAQISGLDANSDVVAEAVNAYNATK
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: HOA_XANP2
Sequence: MARPNKDKLYIQDVTLRDGMHALRHQYDLAATRAIARALDRARVDAIEISHGDGLTGSTFNYGFGAHDDAEWIAAVAEECSHAVVTVLLIPGIGTVHDLKHAYEAGARSVRVCTHCTEADVSRQHIEAARELGMDTATFLMMAHMIPPEALAEQARLMESYGAECVYVTDSAGALLPEDYTARVKTLRDALRPETEIGVHTHHNLTLGIANAVAGIEAGAVRVDASLAGMGAGAGNAPLEALIAVLNRKGIDTGCDLYALMDAADDLVRPLQDRPVRVDRESLSLGYAGVYSSFLRHAENAAQTYGVDTREILSELGRRRMVGGQEDMIVDVALDLAEAKAAVA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: NUOD2_STRCO
Sequence: MSTSHASPRETTEGTVYTVTGGDWDEVVQSAARADDERIVVNMGPQHPSTHGVLRLILEIDGETVTEARCGIGYLHTGIEKNLEYRTWTQGTTFVTRMDYLTPFFNEAAYCLGVEKLLGIDDQIPDRATIIRVLLMELNRLSSHLVAIATGGMELGATTIMIYGFRDRELILDIYELITGLRMNHAYIRPGGLAQDLPPGAVDQIREFVKKMNKNLPEYDKLATGNPIFKARMQDVGYLDLAGCMALGATGPVLRSTGLPHDLRKTQPYCGYETYDFDVPTADTCDSYGRFLIRLEEMRQSLRIVEQCLDRLQPGPVMVADKKIAWPAQLALGPDGLGNSLDHIKKIMGTSMEALIHHFKLVTEGFRVPPAQVYTAVESPKGELGVHVVSDGGTRPFRVHFRDPSFTNLQAMAAMCEGGQVADVIVAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YA37B_YEAST
Sequence: MILFLNGRDLQSVGVTSTGLETLDGNVSVTLLQDTEFLSLFNTEVDTGFNIISPVRDRFLFENEWEDTSVQVRESSSSWASGNQDDWTVWSVLGNQSWGGTGSGQDNDSLGLLFENSSDSGGSDGFGGGGWLWSTVSHVIVVWQVSDSLFSNDSGFSHSGNGVDWVVTLGGFTRQHNTVSTIQDSVTDIGNFSSGWSWVVSHGFQHLGSTDNWLTSQVRLSNQFLLDSQDFWGWDFNTQVTSGNHNTVSDLQDFVEVVNTLLVFNLDNDLDVLTLFTQDFSDGQNIVGGSDERSEDHVDTVLDTESQIFLVLFRQSWQIDIGTW
What are the official names of this protein?
Putative uncharacterized protein YAL037C-B.
Protein: LACY_STRTR
Sequence: MEKSKGQMKSRLSYAAGAFGNDVFYATLSTYFIMFVTTHLFNTGDPKQNSHYVLLITNIISILRILEVFIDPLIGNMIDNTNTKYGKFKPWVVGGGIISSITLLLLFTDLGGLNKTNPFLYLVLFGIIYLVMDVFYSIKDIGFWSMIPALSLDSHEREKMATFARIGSTIGANIVGVAIMPIVLFFSMTNNSGSGDKSGWFWFAFIVALIGVITSIAVGIGTREVESKIRDNNEKTSLKQVFKVLGQNDQLMWLSLGYWFYGLGINTLNALQLYYFTFILGDSGKYSILYGLNTVVGLVSVSLFPTLADKFNRKRLFYGCIAVMLGGIGIFSIAGTSLPIILTAAELFFIPQPLVFLVVFMIISDSVEYGQWKTGHRDESLTLSVRPLIDKLGGAMSNWLVSTFAVAAGMTTGASASTITTHQQFIFKLGMFAFPAATMLIGAFIVARKITLTEARHAKIVEELEHRFSVATSENEVKANVVSLVTPTTGYLVDLSSVNDEHFASGSMGKGFAIKPTDGAVFAPISGTIRQILPTRHAVGIESEDGVIVLIHVGIGTVKLNGEGFISYVEQGDRVEVGQKLLEFWSPIIEKNGLDDTVLVTVTNSEKFSAFHLEQKVGEKVEALSEVITFKKGE
What is the function of this protein?
Responsible for transport of beta-galactosides into the cell, with the concomitant uptake of protons (symport system), and also for transport of homologous and heterologous exchange of beta-galactosides.
What are the official names of this protein?
Lactose permease, Lactose transport protein, Lactose-proton symporter.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the sodium:galactoside symporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.