PharMolix/UniProtQA huggingface dataset:
Protein: FUS_HRSVA
Sequence: MELLILKANAITTILTAVTFCFASGQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPPTNNRARRELPRFMNYTLNNAKKTNVTLSKKRKRRFLGFLLGVGSAIASGVAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEINLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGMDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLHNVNAGKSTTNIMITTIIIVIIVILLSLIAVGLLLYCKARSTPVTLSKDQLSGINNIAFSN
What is the function of this protein?
Major determinant of the species specificity of RSV infection (PubMed:12663767).  The trimer of F1-F2 (F protein) also facilitates the attachment to host cell by binding to host heparan sulfate (PubMed:10864656).  F protein is involved in the entry into the host cell through the interaction with host IGFR1 (PubMed:32494007).  This interaction activates PRKCZ/PKCzeta that recruits host NCL/nucleolin to the apical cell surface where it can bind fusion glycoprotein F1 (PubMed:32494007).  Later in infection, F protein expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (PubMed:10438814).  F protein seems to trigger p53-dependent apoptosis (PubMed:18216092).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
[Fusion glycoprotein F0]: Host Golgi apparatus membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Fusion glycoprotein F1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein. Note=Localized at the host apical membrane. SUBCELLULAR LOCATION: [Fusion glycoprotein F2]: Virion membrane. Host cell membrane. Note=Localized at the host apical membrane.
Protein: NU1M_DROBF
Sequence: MEFILSVVGSLLLVICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLIVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALIGFKILLFSLL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DEOC_COCIM
Sequence: MSSLNNEEWDLLISGKKATLQYPIPLLCYPAPEVVSIAQIIDHTQLSLSATGSQIDVLCAEAKEYGFATVCVRPDYVSRAVQYLQGTQVGVTCVIGFHEGTYSTDQKVSEAKRAMQNGASELDMVMNYPWLSEKRYTDVFQDIRAVRLAAKDAILKVILETSQLTADEIIAGCVLSSLAGADYVKTSTGFNGPGASIENVSLMSAVCDSLQSETRVKASGGIRTIEDCVKMVRAGAERLGASAGVKIVNETRLGNRQVDEPMEPTNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDD_AERS4
Sequence: MHPRFAKPLDTLSAPLKAALLPMLDNDFQARFTPQQVATLKAATGLEDRALRLALLPLAAACSVAPISKFFVGAIACGLSGTWYFGANMEFAGQGLFHSVHAEQSAISNAWLGGETGISEITVNYTPCGHCRQFMNELSTAKTLQVSLPDDLSALQSFLPHSFGPADLDITDALMSPQAHDELVLESEDPIWRAALAAARQSYAPYSQGYAAVALLFADGRLFCGRYAENAAFNPSLPPMQMACAHAVLCGEDLASIRRAVLLESKNGQISQRDSAQSTLKALGSVELEYQAV
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: ATPA_ACIFI
Sequence: MQQLNPSEISELIRARIAGFEGRVETRSQGTIISLSDGILRIHGLEDVMYGEMLELPGGRFGLAMNLEQDNVGAVVLGEFSGLQEGDVVKCTGRVMQVPIGKALLGRVVNALGQPVDGKGAIDAEEFDVLEKIAPGVIDRQSVDEPMQTGIKSIDAMVPIGRGQRELIIGDRQTGKTAVAVDAILNQKGKDVQCIYVAIGQKASTVAGVVRKLEEYGAMEYTTVIAANASESAAMQYLAPYAGCTMGEYFRDRGMNALIVYDDLTKQAWAYRHISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADFVEKFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIYLETDLFNAGIRPAINAGLSVSRVGGAAQTKIIKKLGGGIRLDLAQYRELAAFAQFASDLDEITRKQIERGKRVTELLKQDQFSPMSVADEGAALFAASSGALDDVEVANVRPFEKALLAYLNSNNKELMAGIEEKKDLTDDLKKQLDAAVKQFKSGSTY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PFF1_YEAS7
Sequence: MKLKSVFRSVLKYRKTNLSLLLLITYSIITLLYIFDHERYKLNLPKEDEHPEFNDLLETAWGDLQIITASFHPYTSKENDKVHDYLLKRVLEITGNSSFASVSDDKESERSILFQQQDPFNESSRFSRVTYFESSNILVKLEGKNPEEEGLLLSAHFDSVPTGYGATDDGMGVVSLLANLKYHIKHRPNRTLIFNFNNNEEFGLLGASTYFNHSWSNLTKYVINLEGTGAGGKAVLFRTSDTSTAKIYQQSVKENPFGNSIYQQGFYSRYVRSETDYKIYEENGMRGWDVAFYKPRNLYHTIKDSIQYTSKASLWHMLHTSLQLSAYVASNSLDTADQTPACYFDFIGLKFFVISAKTLFYWNCIFLLVSPVVAIGLYLISRDRMTWKSHSWLSWTRFPLSLAAGIIVQKLFSNDIIRSNPLTFSRNYFWPISAFFTQVIFTSYVLINCSNFFFPCADMKSLSIIELFIILWTILLFTSKLLYSSDYRYTGLYPLSIFFLLSTIAAILRLLALALGMRTRKRLGRECRDHHSNYSSHSQIDMERDGQENLEQPQDQFTSSQDDQASIQDDNVSTTSAGPSHNVDEDHGMDSSSQQHDERVPLLKGSNSMEEGLSTRENSLKLEYTDYAWIIQFLLIVPIPSFILFNSVDVIMDALNHTVQEGSKATFDVLRFGMVGSILMALPILPFFYKVNYITISLTALLFLISASKTLLVHPFTNSNPLKVRFSQNIDLSQGNAASVHVLGREGNFLKPMLQDLPSIKYSSTHINCTSVTNGMELCMYDGMQPNLLSTNGNTNISSMVKVHVLHNNRNSTERSPYEPIVAELLLEVKENRACTLTFESRHQAKSPVREITVYQKKNSAPQKANITKTIKSASGINELQLHKLDFDQETYHIGVQWFPKLLTDGNLEDDKLGTKDELSVSISCYWGEYDSESVVNGTAVRKIPAFDELINYAPLSFSFTNEQKGLVIVKDAIIL
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: LIPB_FRATW
Sequence: MNNIYQKDLGLQQYTKVFEDMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSHNIPIVATDRGGQVTYHGPGQAVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAHIIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLTPFSYINPCGYSGLKMCQLANFYQEADIKKVQQQYTAEFVTLLNNSI
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM3B2_BOTJA
Sequence: RQNRHEASCRIVSPPVCGNELLEKGEECDCGSPRNCRDPCCDAATCKLHSWVECESGECCDQCRFIKAGNVCRPQRSECDIAESCTGQSAQCPTDDFHKNGQPCLSNYGYCYNGNCPIMHHQCYALFGSGAIVAQDGCFKFNDRGDKFFYCRKENVIITPCAQEDVKCGRLFCHTKKSECDFDYSEDPDYGMVDHGTKCADGKVCNSNRQCVDVTTAY
What is the function of this protein?
The hemorrhagic metalloproteinase-disintegrin-like bothrojarin-1 is a potent inhibitor of collagen-induced platelet aggregation by blockage of alpha-2/beta-1 (ITGA2/ITGB1) integrin.  It does not present any fibrinogen-clotting activity (By similarity).
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like bothrojarin-2, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FHUB_SALTY
Sequence: MSRKREMPDGGAKSVLSDLRFGRFVGRIRRSRHPALLLLALFVAACWLTWVNFSVALPRSQWQQAIWSPDIDIIEQMIFHYSQLPRLAISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLGITVTTLWAIPGALTTQFAALTGACIVGALVFGVAWGKRLSPVTLILAGLVVSLYCGAINQLLVIFHHDQLQSMFLWSTGTLTQTDWSGVQRLWPQLLGGVMLTLLLLRPMTLMGLDDGVARNLGLALSLARLAALSLAIVLSALLVNAVGIIGFIGLFAPLLAKMLGARRLLARLMLAPLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLKSMSAPDMNASDRVAAERRHVLAFAVAGGALLLLATWVALSFGRDAHGWTWASGTLLEELMPWRWPRILAALMAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWLLPAGSLGAAATLLIIMIAAGRGGFSPQRMLLAGMALSTAFTMLLMMLQASGDPRMAEVLTWLSGSTYNATGGQVTRTAIVMVILLAIVPLCRRWLTILPLGGDAARAVGMALTPSRIALLALAACLTATATMTIGPLSFVGLMAPHIARMLGFRRTMPHMVISALAGGVLLVFADWCGRMALFPYQIPAGLLSSFIGAPYFIYLLRKQSR
What is the function of this protein?
Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import.  Responsible for the translocation of the substrate across the membrane (By similarity).  Involved in ferrioxamine-mediated iron(III) utilization (PubMed:10103258).
What are the official names of this protein?
Iron(3+)-hydroxamate import system permease protein FhuB, Ferric hydroxamate uptake protein B, Ferrichrome transport system permease protein FhuB, Ferrichrome uptake protein FhuB, Iron(III)-hydroxamate import system permease protein FhuB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SWT7C_ORYSI
Sequence: MVSPDLIRNVVGIVGNVISFGLFLSPVPIFWWIIKNKNVQNFKADPILVVTINGISLVIEAVYLTIFFLFSDKKNKKKMGVVLATEALFMAAVAVGVLLGAHTHQRRSLIVGILCVIFGTIMYSSPLTIMVVKTKSVEYMPLLLSVVSFLNGLCWTLYALIRFDIFITIPNGLGVLFAIMQLILYAIYYRTTPKKQDKNLELPTVAPIAKDTSIVAPVGNDDDVNGSTASHATINITIEP
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET7c, OsSWEET7c.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL22_SHESW
Sequence: MEVLAKHRFARTSAQKARLVADQIRGLPVAKALEILTFSPKKAAVLVKKVLDSAIANAEHNEGADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RNFB_BUCAT
Sequence: MITLIIFSFLSFLLGIILSFTAYKFRSQEDPIVEIVNELLPQSQCAQCGYSGCYPYAKAIVENSEKINKCIPGGTDLISAISSVLSIEVPEKNLIITHKKQKNNTVLINESNCVGCSKCASFCPVDAIVGAPNFIHTVLQEFCTGCNICLLHCPTNCIEIKKETYEE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: EFP_COXBN
Sequence: MATHSTNEFRGGLKVMVDGDPCSIIDNEFVKPGKGQAFNRVKFRNLKTGRVLERTFKSGETLPAADVVEVEMQYLYNDGEFWHFMTSENYEQHAASKEAVAEAKQWLKEEALCMVTMWNGVPLSVEPPNFVELKITETEPGVRGDTATGGTKRAKLETGAVVRVPLFLNEGEIIKVDTRRGEYVSRAK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y345_METJA
Sequence: MDCVTNATTRCRKGSIVVIVMPPLISNNTFFLMNTTNDGNGGSVSYDYPLLSNQNSLITNTTNNLTSDSTNTDISNETPILSNNTPILMNTPTNPNSDSDTTTPTVVSHTVELITEEKKVISKIVYSDGTEDVKELDLTDFYNSAYNEGYSAGVNSVDFSKTGYIIENGIIKVTTTLTNGKSQEYNITLDENLVVSLYNQIMANKSSCFQIRQNETEYSFLVESRQYQPQPNLAYQPAVDGTPVYEVLGQEQKTWSFTLYVDSIPKMQFLQQLASNPLIEVYFDEIGDWKQALIQSISLSRITTGHYYADIELIILE
What are the official names of this protein?
Uncharacterized protein MJ0345.
Protein: SORR2_PENRW
Sequence: MENGCTSHWLLSRIAGSESRLANNRAFRCGSIEKAASYLIGELLIINQAEAKSNKRLPKFVHKADTYHKACARCKARGKTCAYGQGAVEKQTVHKPRGQASSVHMPVPMLVPPISSAPSLETPPESVAASPPTVDSIPVSHHVNEDPEAEPDLEKNRAYYTAHGRFAGQVAAAINERAGLIPATCNQVPLVDAPLFGDLNLPSQSCALSSSTELPPRAYADQLIDIYWQHVDPMEPVLDRQRFLENYEKAYSTPITPLCADYDLWLGILNVVFALAVQRQELNPLHQRNEEANRFFQRAWVLLPAESMLWKPGSLELVQCLMLMNRYLHCTNNQQKTWTTAGLAMRIAQSMCCHLTETPLLKGSSDDKALKQKVWASCVALDRCISWSLGKTSALVLIPSPPPSSPQQLGENAMHDTLGLRLHEIGNQIQLAQIQNRTSLAARFRPPLLSQQDEYHNAALQLDACLQDWENSIPSDWQPRNLRMVTDRSSRAERYLLHLRYLHHRIFLYRPMLARFYAMKPDTQPLHKSPSLSHRLLRESASMCIEAAQQVASLVNETLEPDEPIGLLPWWYRIYYLHIAGANFLAAMFRSELFTDSVSQSWESVMLALRAHEHLSPYVQQCLWTFETLAARITGKPYPSMDGGGCGLMVDGSSGVSFDDIFKDINFDFDNFIFGPEDFGEGLV
What is the function of this protein?
Transcription factor that acts in concert with sorR1 which is a transcriptional activator of the gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria (PubMed:28618182).
What are the official names of this protein?
Sorbicillinoid biosynthetic cluster transcription factor 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: THADA_MOUSE
Sequence: MGVKKKREMQVAALTVCHQDMETLRSFADMEGKNLASLLLHCVQLTDGVSQIHSIKQIVPLLEKVDKNGVCDPAIQSCLDILAGIYFSLTLKNPLKKVLASSLNGLPEVFLTQATHSFTFHLQEELDTADLYSYRKVMDNISSCMENFNLGRASVVNLLKDVLHFLQKSLIEILEENRKFAGNRIVQTQLMSDLLVGVRVAMTLVQKVQGPQGSLWNDSSSPIWQSMCGLLSIFTKFLNDDDLLQTVESTSGLAVILFIKTMFRPSEKLPGLISSLLLRSAECTSIPEWLMNSCRSLCCTDVPASTLLFLCQGTLAMLDWQDGSMGPSGEALLLDIVHVLFTLSSQIKESTLDMFLSRILASWTSSAIQILESGSSGLKGHLNGDSCVPRRLLEYVYTHWEHPLDALRHQTKVMFRNLLQMHRLTMEGADLATDPFCLELTKSLLQLEWHIKGKYACLGCLVETLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRILNYSPESLHYMVHILQASTDTGTGSCNHRGALGALMACLRTARAHGHLQSATQAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESNRSTEVVSTEEMQWVQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSTPDSENGSIREQPSVTLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSVAEVFPDPEGNIQTVYQLSHDIDAGRYQILMECFTSTFEEVKTLAFDLLMKLSSVTAGQFQDSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIRQDALPAVLSASSPQQLTRGAGETSAVLERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQRLPLNDLRLASEWRPLLGRLLLLSYRLSTVVAPVIQSSSPEGLIPVDTDSASASRLQLILNEIQPRDTNDYFNHTKILKECDSFDLEDLSTSVSNIDSSAEVKGKEEKACDVTAQMVLACCWRSMKEVALLLGTLCQLLPVQPGPESSNVFLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLRSVLEEIKGSDPSSKLCATRRSAGIPFYIQALLASEPKKSRMDLLKITMRELISLALSADDSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDEVSKTNRMTGREFFSRFPELYPFLLKQLETVASTVDSELGEPDRHPGMFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFIMIDQIPSTLCALLNSLPNSTDQCFRQNHIHGTLLQVFHLLQAYITDCRHRTNADFLQELSDVTACTKAKLWLAMRQNPCLVTRAVYIDILFLLTNCLDRPEEGKQTALESLGFWEDVRRIILESELIKGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAKGQATAVPLSFSRLLKSSFPEVRLLALDTLLERARSSEQEQKEPLPLLCSMGEELLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECYAHLSPKEFLMWSMDIASNDRSEIQGVALKLASKIIAYRVQSCEKNKDSLAPELRQWVQLVVWSCGDHLPTASRLAVAEVLTSTAPLFLTSPQPILELQGTLSLWRCVLTLLQSEEQTVREAATEIVTTAMSQGNTCQSTEFAFCQVDASIALTLALAVLCDLLQQWDQLEPGLPILLGWLLEEGDDLEGHVQSPHQGEEEHIFEKSEVNFWAETLTFVKSLCRQLFHLLCQSGWQSPHSQKLCHLQRIASEQSHLISQLFRELPLSAEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEGLRAEDCPREWRQVMAPRTEAAC
What are the official names of this protein?
Thyroid adenoma-associated protein homolog.
What is the protein family that this protein belongs to?
Belongs to the THADA family.
Protein: CH10_BUCAP
Sequence: MKIRPLHDRVLVKRNEAELKSAGGIVLTGSAAAKSTRGTITAVGNGRVLDNGQIKPLDVKVGDVVIFNEGYGAKTEKIDNEELLILNESDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2936_BACLD
Sequence: MDLWVVILVGVLALLAGVALGFFIARKYMMNYLKKNPPINEQMLRMMMMQMGMKPSQKKINQMMKAMENQTK
What are the official names of this protein?
UPF0154 protein BLi02038/BL02936.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PANB1_PSEAB
Sequence: MSSHRPQHRLSVPDIQRRKGAGSLVALTAYSTPMARLLDPHADLLLVGDSLGMVLYGMPSTLGVSLEMMVAHTLAVMRGSRRACVVADLPFASYQESPRQAFRNAARLLADSGAQAVKLEGGEEMEETVDFLVRRGIPVLAHIGLMPQQVNAMGGFKAQGRDPESAERVRRDGLAMQRGGAFAVVIEGVGEPLARRLSEELAIPCIGIGASPACDGQVLVSEDLLGLSGEQVPRFVERYARLDREIDEAARRFAEDVRERRFPEARHCFAMRE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 1, Ketopantoate hydroxymethyltransferase 1, KPHMT 1.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_YERPG
Sequence: MSASGEISTPRDYIGHHLNHLQLDLRTFELVNPHSTGPATFWTLNIDSLFFSVVLGLAFLLVFRKVAASATSGVPGKLQTAVELIIGFVDNSVRDMYHGKSKVIAPLALTVFVWVLLMNMMDLLPIDLLPYIGEHVFGLPALRVVPTADVSITLSMALGVFILIIFYSIKMKGVGGFTKELTMQPFYHPIFIPVNLILEGVSLLSKPLSLGLRLFGNMYAGELIFILIAGLLPWWSQWMLSVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRUA_CHLTB
Sequence: MTKKIVLQIAYQGTSYSGWQYQPNALSIQEVLKTILKKIAGFRISVISSGRTDAGVHAQGQIAHFHCPDHPHFTDPRQIQKMLNALLPHDIVIRDAVMTDGDFHSRFSAIAKEYRYTLSLLPKPLPHHRLFCFSPRYKLNIARMQEAAQYLVGTHDFASFANLGREYSSTIRTLYTLDLSEQEHLVTVICRGNGFLYKMVRNIVGALLDIGKGKYPPEHLLDMLATKDRRKGPPSAPPYGLSLHHVCYPPPYQWFCKHEHNNSSEGK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LAZY1_MAIZE
Sequence: MKLLGWMHRKLRQNSNDVFKEFNNAAGGTCNCITGLAASDPATFLATANEYFTADNDFTNNHPSSPAADLFTFGGSGLLTIGTLGIAAVAVSADADEVDYDVDADADSDFDDNDDTAGDDEDQVDSAVTPTFTYAAPPPIEDATVVEKAAVAVVEAIAEKDDDTTTEDDLMVVSAELEKVLGGRNSGTAGDLVASARVSFAMGVDCPLQGFLFGSPVSDAESRLEQPRDSNGGRRTSLGELFMRTRFAEEKVALVAVEEGEDGGDIGAGGERDDRKAGKGGGGHKTTKKRSAKDEKVPRGDGAQASATVTKSKFHKILQIFHRKVYPESAALARNLTKKSRKRGSGAYHKPEPAASKLRCLKEQRAPGFGCCASRASFGGAASPIDGDDDDELNGSKSGHWIKTDAEYLVLEL
What is the function of this protein?
Involved in the regulation of shoot gravitropism, and tassel and ear development through the regulation of polar auxin transport (PAT) and auxin signaling.  Acts as negative regulator of basipetal PAT, but positive regulator of lateral auxin transport (PubMed:24089437).  Involved in the regulation of shoot gravitropism and leaf angle through the regulation of cell development (PubMed:24987012).
What are the official names of this protein?
Protein LAZY 1, ZmLA1, Protein CONTROLLING LEAF ANGLE 4, ZmCLA4, Protein PROSTRATE STEM 1.
What is the protein family that this protein belongs to?
Belongs to the LAZY family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Nucleus.
Protein: HEMH1_ARATH
Sequence: MQATALSSGFNPLTKRKDHRFPRSCSQRNSLSLIQCDIKERSFGESMTITNRGLSFKTNVFEQARSVTGDCSYDETSAKARSHVVAEDKIGVLLLNLGGPETLNDVQPFLYNLFADPDIIRLPRPFQFLQGTIAKFISVVRAPKSKEGYAAIGGGSPLRKITDEQADAIKMSLQAKNIAANVYVGMRYWYPFTEEAVQQIKKDKITRLVVLPLYPQYSISTTGSSIRVLQDLFRKDPYLAGVPVAIIKSWYQRRGYVNSMADLIEKELQTFSDPKEVMIFFSAHGVPVSYVENAGDPYQKQMEECIDLIMEELKARGVLNDHKLAYQSRVGPVQWLKPYTDEVLVDLGKSGVKSLLAVPVSFVSEHIETLEEIDMEYRELALESGVENWGRVPALGLTPSFITDLADAVIESLPSAEAMSNPNAVVDSEDSESSDAFSYIVKMFFGSILAFVLLLSPKMFHAFRNL
What is the function of this protein?
Catalyzes the last step of heme biosynthesis by inserting ferrous iron into protoporphyrin IX to produce protoheme (PubMed:17416636, PubMed:24329537).  Produces heme for photosynthetic cytochromes, but does not seem to be involved in stress responses (PubMed:24329537).  May be involved in wound-induced supply of heme to defensive hemoproteins outside plastids (PubMed:17416636).  Regulates the expression of photosynthesis-associated nuclear genes in undevelopped chloroplasts through production of heme (PubMed:21565502).
What are the official names of this protein?
Ferrochelatase-1, chloroplastic/mitochondrial, AtFC1, Ferrochelatase-I, AtFC-I, Heme synthase 1, Protoheme ferro-lyase 1.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Peripheral membrane protein. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein. Mitochondrion. Note=(PubMed:9346891) describes experimental in vitro import of FC1 into mitochondria isolated from pea. However, (PubMed:11602264) shows experimental evidences that FC1 is not present in Arabidopsis mitochondria in vivo.
Protein: RL19_THEYD
Sequence: MNQLIIRAIEERFKKSNIPDFKPGDTVKVHVKVKEGDKERIQVFEGVVIARRGGGLRETFTVRKISFGVGVERVFPLHSPIIDKIELVRRGDVRRAKLYYLRTKKGKEAKVKEKTDYQKA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ANR10_HUMAN
Sequence: MSAAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLATLCSLLQQTPHAHLASEDSFYGWTPVHWAAHFGKLECLVQLVRAGATLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVANGAHVDLRNASGLTAADIAQTQGFQECAQFLLNLQNCHLNHFYNNGILNGGHQNVFPNHISVGTNRKRCLEDSEDFGVKKARTEAQSLDSAVPLTNGDTEDDADKMHVDREFAVVTDMKNSSSVSNTLTNGCVINGHLDFPSTTPLSGMESRNGQCLTGTNGISSGLAPGQPFPSSQGSLCISGTEEPEKTLRANPELCGSLHLNGSPSSCIASRPSWVEDIGDNLYYGHYHGFGDTAESIPELNSVVEHSKSVKVQERYDSAVLGTMHLHHGS
What are the official names of this protein?
Ankyrin repeat domain-containing protein 10.