PharMolix/UniProtQA huggingface dataset:
Protein: DESM_HUMAN
Sequence: MSQAYSSSQRVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTYSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL
What is the function of this protein?
Muscle-specific type III intermediate filament essential for proper muscular structure and function.  Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity (PubMed:25358400).  In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures (PubMed:24200904, PubMed:25394388, PubMed:26724190).  May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.  Contributes to the transcriptional regulation of the NKX2-5 gene in cardiac progenitor cells during a short period of cardiomyogenesis and in cardiac side population stem cells in the adult.  Plays a role in maintaining an optimal conformation of nebulette (NEB) on heart muscle sarcomeres to bind and recruit cardiac alpha-actin (By similarity).
What are the official names of this protein?
Desmin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm. Cell membrane, sarcolemma. Nucleus. Note=Localizes in the intercalated disks which occur at the Z line of cardiomyocytes (PubMed:24200904, PubMed:26724190). Localizes in the nucleus exclusively in differentiating cardiac progenitor cells and premature cardiomyocytes (By similarity).
Protein: LDH_BORBZ
Sequence: MLKSNKVVLIGAGGVGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLKKNINVLFGTYKDCANADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVDIMTYVTMKYSKFPIHKVIGTGTILDTSRLRYFLSDHFNVNTQNIHSYIMGEHGDSSFATWDETKIAMKPLSEYLAEGKITELELDEIHKKVVNAAYEVIKLKGATYYAIGLGIKNIVNAIIGDQNVILPISSYINGQYGGLIKDIYIGAPAIVCKEGVKEVLNFKISPKELDKFNSSANQLKSYIDKMEF
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_STAAC
Sequence: MKVIFTQDVKGKGKKGEVKEVPVGYANNFLLKKNYAVEATPGNLKQLELQKKRAKQERQQEIEDAKALKETLSNIEVEVSAKTGEGGKLFGSVSTKQIAEALKAQHDIKIDKRKMDLPNGIHSLGYTNVPVKLDKEVEGTIRVHTVEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: CBID_METC4
Sequence: MNSETGALRRGWTTGTCASAAARAAFEALLGIEPEDPVPVTLPSGARPTFALARLDRGSGFVRAGIVKDAGDDPDVTHGALVLATLRFGAPATGIVFRAGPGVGIVTKPGLPLPPGEPAINAMPRRMIRTALTEVAEANGVTCDLVVEVGIEDGERIAERTMNRRLGIIGGLSILGTTGVVVPYSCAAWIASIHRGIDVARAEGLTHLAGATGATSEAAIRNLYGLPEQALIDMGDFVGGMLKYIRGHPVARVTIAGGFAKMTKLAQGRLDLHSKREAIDFRWLAELYCSIGGKAESGMSVRTANTALEVLQMAQAEHVPIAPAIARSACRVAAGALARADIALDVAIFDRDGCLIASERC
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: EPHX3_MOUSE
Sequence: MPEFVVTALLAPSRLSLKLLRALVMSLVYLAALVAAFVYSCIALTHVMCRPRRGCCGRQRLSPPECLRDPTLGEHCFLTLRVSVPPVKSSGLRLHYVSAGHGNGPLMLFLHGFPENWFSWRYQLREFQSHFHVVAVDMRGYSPSDAPKEVDCYTIDLLLDDIKDTILGLGYSKCILVSHDWGASLAWEFSIYYPSLVERMVVANGPPMSVIQEYSIHHIGQIFRSNYMFLFQLPWLPEKLLSMSDFQILKDTFTHRKNGIPGLTPSELEAFLYHFSQPGCLTGPINYYRNVFRNFPLEPKKLSTPTLLLWGEKDFAFQQGLVEAIGRHFVPGRLESHILPGSGHWIPQSHPQEMHQYMWAFLQDLLG
What is the function of this protein?
Catalyzes the hydrolysis of epoxide-containing fatty acids.  Active in vitro against epoxyeicosatrienoic acids (EETs) including 8,9-EET, 9,10-EET, 11,12-EET and 14,15-EET and leukotoxin.
What are the official names of this protein?
Epoxide hydrolase 3, EH3, Abhydrolase domain-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein.
Protein: RRF_SHESH
Sequence: MINEIKNDAKSRMEKCVESTKTQMAKVRTGRAHPSLLDTIKVSYYGSMTPLKQVGNVSIEDSRTLAVNVFDSTMIQAVEKAIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAEAENGRIAVRNVRRDANSDVKSLEKEKECTEDDVRRTEDDVQKFTDAHIKLIDEILTAKEAELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNAI_ECO57
Sequence: MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHAVQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFEKQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAGKDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKITTFDNRPLYVPNSLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLVYFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMDNITPPEQGR
What are the official names of this protein?
Low conductance mechanosensitive channel YnaI.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIPE_DROME
Sequence: MGDEQDKRTGKEKLLFYTTAFFILLGTFSLFAFLFLVPFVIEPAFTTIFMQFEEVPALCETYDTEIYYGAKNCSWSSCREGCTKDIYTCTQIRVNYRLNLYNFTDEFNFTEYHINLKEAERILPPVKRTDRYERALRSDYEYDNLGGGTGLDIDLGAGRMEQLNFGDADGSNGYLIEDSEDTRGLSASGTLISDERRPFDEISELNEGLMGNRSMYYYVGARLFPNVKGCGYPPMLNCTIWLKRYTKIGMKFPCYYSKVDPSLVISDLDYWQNTLNLVYSMAIPIPSFIISVIYLTYAYFKIYNEDEETAPLDKNAEDMDIDDIDAVDDSDGAVLADNVAGSQIINMDSTTNDSCLEGVLPNGGPGMTASISQGGSVTTPGPYIAQSPAGSQMTPNSEINSFGHQLKVQMADELSRDSLENGAISTSNSVQGNLSKTMTTSISTPPGPTAAV
What is the function of this protein?
Enhances para sodium channel function.  Required during pupal development to rescue adult paralysis and also protects adult flies against heat-induced lethality.
What are the official names of this protein?
Protein tipE, Temperature-induced paralytic E.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NBP21_DROYA
Sequence: MLEKVKNIIVVLSGKGGVGKSTVSTQLSLALRKNGFKVGLLDIDLCGPSVPYLLGLEGRDIFQCDEGWVPVYTDESQTLAVMSIGFLLKNREDPVIWRGPKKTMMIRQFLTDVRWDELDYLIIDTPPGTSDEHITVMECLKEVGCHGAIIVTTPQEVALDDVRKEITFCKKTGINILGIVENMSGFVCPHCTSCTNIFSSNGGASLANYAQVPHLGTLPIDPRVGVLAGSTTSVLDELPDSTTAEVLTHIVEKLKTIFVS
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_MYCBT
Sequence: MTRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQVATTLTGTQRIVAADCVVVACDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHGVIRLQDNKTVYRSAETAITTVYFGTPSASDLEAYLASGESLRVAGGFTLDGLGGWFIDGVQGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBCD_DICDI
Sequence: MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI
What is the function of this protein?
Tubulin-folding protein; involved in the first step of the tubulin folding pathway.
What are the official names of this protein?
Tubulin-specific chaperone D, Tubulin-folding cofactor D.
What is the protein family that this protein belongs to?
Belongs to the TBCD family.
Protein: TSAD_HAMD5
Sequence: MRVLGIETSCDETGVAIYDSESGLLADQLYSQVKLHAQYGGVVPELASRDHIRKIVPLIQATLKEACVSPQEIDAVAYTAGPGLIGALLVGASVGRALAFAWNVPAVPVHHMEAHLLAPMLEDQVPDFPFIALLVSGGHTQLVQVNAIGKYALLGESLDDAVGEAFDKTAKLLGLEYPGGAMLAHLAQQGDPDRFIFPRPMIDRPGLDFSFSGLKTAAALTIRANHQDEQTRCDIAYAFEKAVIDTLAIKSERALEQTGLTRLVLAGGVSANEKLRSKLSVIMHERQGKVFYARPQFCTDNGAMIAYAGWRRIQEGSRSDLSISVHPKWALSQ
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_STAHJ
Sequence: MPTINQLVRKPRQSKSKKSDSPVLNRGFNSKKKQFTNLNSPQKRGVCTRVGTMTPRKPNSALRKYARVRLSNNIEINAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDTSGVDGRRQGRSLYGTKKPKN
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MB12A_HUMAN
Sequence: MDPVPGTDSAPLAGLAWSSASAPPPRGFSAISCTVEGAPASFGKSFAQKSGYFLCLSSLGSLENPQENVVADIQIVVDKSPLPLGFSPVCDPMDSKASVSKKKRMCVKLLPLGATDTAVFDVRLSGKTKTVPGYLRIGDMGGFAIWCKKAKAPRPVPKPRGLSRDMQGLSLDAASQPSKGGLLERTASRLGSRASTLRRNDSIYEASSLYGISAMDGVPFTLHPRFEGKSCSPLAFSAFGDLTIKSLADIEEEYNYGFVVEKTAAARLPPSVS
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.  Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.  May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.
What are the official names of this protein?
Multivesicular body subunit 12A, CIN85/CD2AP family-binding protein, ESCRT-I complex subunit MVB12A, Protein FAM125A.
What is the protein family that this protein belongs to?
Belongs to the MVB12 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane; Peripheral membrane protein. Note=Colocalizes with F-actin. Some fraction may be nuclear.
Protein: TXAG6_AGEOR
Sequence: MRFYIAFFFLLLAADMALSFEIGNSEELERLSMVYGEVESERGCTHGSCENGETCCDGWRCRYTGRAVPFMCVP
What are the official names of this protein?
U6-agatoxin-Ao1a, U6-AGTX-Ao1a, AgorTX_A4.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBJ_SORBI
Sequence: MADTTGRIPLWLIGTVTGILVIGLIGVFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: IRF6_HUMAN
Sequence: MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQPQGSIINPGSTGSAPWDEKDNDVDEEDEEDELDQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPEAVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSGPCAPSLVAPNLIERQKKVKLFCLETFLSDLIAHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLYRILQTQESWQPMQPTPSMQLPPALPPQ
What is the function of this protein?
Probable DNA-binding transcriptional activator.  Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity).  Plays a role in regulating mammary epithelial cell proliferation (By similarity).  May regulate WDR65 transcription (By similarity).
What are the official names of this protein?
Interferon regulatory factor 6, IRF-6.
What is the protein family that this protein belongs to?
Belongs to the IRF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Translocates to nucleus in response to an activating signal.
Protein: DIA_DROME
Sequence: MSRHEKTKSTGGGLLDSLFGRPSKSKGGTISSGTLAHGGRPVSADNYVVPGVEDFEQYIQQLSVAELDAKFLEIIEDMNIPKDKREPLLAKSKEERQKMIMWHLKGKNSLERSANSRFEKPIDYVEYLQNGEHSTHKVYQCVESLRVALTSNPISWIKEFGVAGIGTIEKLLARSKNNASYEKIEFEAIRCLKAIMNNTWGLNVVLNPDQHSVVLLLAQSLDPRKPQTMCEALKLLASFCIVYERNGYEKVLRAITTIAATSFKASERFRPIVDALFASDQQDPKRDLACHSLIFINTLTNTPTDLNFRLHLRCEIMRMGLYDRLDEFTKIVEASNNENLQQHFKIFNEIREDDFEEFVQRFDNVTFNMDDATDCFDVLKNLVTDTTSEPYFLSILQHLLYIRDDFYFRPAYYQLIEECISQIVFHKGYCDPNFENRNFNIDTSLLLDDIVEKAKAKESKRSEEYEKKIEQLESAKQEAEAKAAHLEEKVKLMEANGVAAPSPNKLPKVNIPMPPPPPGGGGAPPPPPPPMPGRAGGGPPPPPPPPMPGRAGGPPPPPPPPGMGGPPPPPMPGMMRPGGGPPPPPMMMGPMVPVLPHGLKPKKKWDVKNPMKRANWKAIVPAKMSDKAFWVKCQEDKLAQDDFLAELAVKFSSKPVKKEQKDAVDKPTTLTKKNVDLRVLDSKTAQNLAIMLGGSLKHLSYEQIKICLLRCDTDILSSNILQQLIQYLPPPEHLKRLQEIKAKGEPLPPIEQFAATIGEIKRLSPRLHNLNFKLTYADMVQDIKPDIVAGTAACEEIRNSKKFSKILELILLLGNYMNSGSKNEAAFGFEISYLTKLSNTKDADNKQTLLHYLADLVEKKFPDALNFYDDLSHVNKASRVNMDAIQKAMRQMNSAVKNLETDLQNNKVPQCDDDKFSEVMGKFAEECRQQVDVLGKMQLQMEKLYKDLSEYYAFDPSKYTMEEFFADIKTFKDAFQAAHNDNVRVREELEKKRRLQEAREQSAREQQERQQRKKAVVDMDAPQTQEGVMDSLLEALQTGSAFGQRNRQARRQRPAGAERRAQLSRSRSRTRVTNGQLMTREMILNEVLGSA
What is the function of this protein?
Required for cytokinesis in both mitosis and meiosis.  Has a role in actin cytoskeleton organization and is essential for many, if not all, actin-mediated events involving membrane invagination.  May serve as a mediator between signaling molecules and actin organizers at specific phases of the cell cycle.  Possible component of the contractile ring or may control its function.
What are the official names of this protein?
Protein diaphanous.
What is the protein family that this protein belongs to?
Belongs to the formin homology family. Diaphanous subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cleavage furrow. Note=Localizes to the site where the metaphase furrow is anticipated to form, to the growing tip of cellularization furrows, and to contractile rings.
Protein: Y1927_SHEAM
Sequence: MEFWKTKRLEELNPEEWESLCDGCGKCCLNKIIDDETDELYYTNAACKLLDRDACHCRHYSERFTFVPGCAAITPDNIASLTWLPDSCAYVRLFQGRDLPSWHPLVTGSKEAMHAAGMSVKGKAVCETKVRYLEDHIVLWPLKDVD
What are the official names of this protein?
UPF0260 protein Sama_1927.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: LOX6_ORYSJ
Sequence: MELTGLTRAAAAATVTPPAPRRGWGELRFAPLLPGERHGRRKVVVAAISEEVPRLAASPSSGIKGGGAGERRPAPEKVALRAALTVRRKQKEDIKEAVAGHLDALWDMVGRNVVLELISTKIHPRTKKPMQSGRVSIKDWCQKRGAKGDHVVYTAEFTVDADFGEPGAIAVANRHNREFFLESIVVEGGGLPCGPVHFACNSWVQSTRELPTKRVFFSNKPYLPSETPPGLRELREKELKDLRGDGTGVRKLSDRIYDYATYNDLGNPDKGKEFIRPILGGEKIPYPRRCRTGRPPTDTNMLAESRVEKPHPIYVPRDEAFEELKQGAFSSGRLRAVLHTLIPSLIASISAETHNFQGFHHIDNLYKEGLRLKLGLQEHLFQKIPLVQKIQESSEGMLRYDTPSILSKDKFAWLRDDEFARQAVAGINPVNIERLQVFPPVSKLDPAIYGPPESSITETHIAGHLNGLTVQQAMDEAKLFIVDYHDAYLPFLDRINAIDGRKAYATRTIFFLTEAGTLKPIAIELSLPPAKPGEPRPSKVLTPPYDATSNWLWMLAKAHVSSNDAGVHQLVNHWLRTHATMEPFILAAHRHMSAMHPIFKLLHPHMRYTLEINALARQSLINADGVIESCFTPGPVSGEISAAYYRNHWRFDLEGLPSDLIRRGVAVEDATQPHGVRLLIEDYPYANDGLLLWSAIRSWVESYVQLYYPDAGTVQCDLELQGWYHESIHVGHGDLRHAPWWPPLSTPVDLASILTTLVWLASAQHAALNFGQYPLGGYVPNRPPLIRRLLPDLERDAAEYAAFLADPHRFFLNAMPGVLEATKFMAVVDTLSTHSPDEEYLGEGRDEGGVPWTADEAAVAAHGMFAADVRRAEETIERRNADHGRKNRCGAGVLPYELLAPSSPPGVTCRGVPNSISI
What is the function of this protein?
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).
What are the official names of this protein?
Probable lipoxygenase 6.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
Protein: VC21_VACCC
Sequence: MLPHTSDTTSTFRLKTVFDLVFENRNIIYKADVVNDIIHHRLKVSLPMIKSLFYKMSEFSPYDDYYVKKILAYCLLRDESFAELHSKFCLNEDYKSVFMKNISFDKIDSIIVT
What are the official names of this protein?
Protein C21/B27.
Protein: MATP_SALPB
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYVEASAAQEAVNLLLALENEPVRVNVWIDRHMNPALLNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFMVWQRLAGLAQRRGKTLSETIVQLIEDAEHKEKYATQMTTLKQDLQALLGKK
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_HALH5
Sequence: MRKYEIMYIIAPNLEEAANKEIIERFNGVLTNQGAEIEKVEEMGKRRLAYEINKFREGYYVLLNVKADADAIAEFNRLIKINDNVIRVLITKDEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RNY_DEHM1
Sequence: MLEFFMETAPTTTTGLPLSAILAIFFSFIIGIVFGGMALFVFRGFIMNRQLRIAQRKATKMLADSKVEAKDVLVEAKREADKARNSAEAELKERRSELAKQENRVMQKTEALDRKLENLEQREQSLTNREKSIDETQSQIEEIRTAELKRLEEVASMTTEQAKSSLLEMLEGEMQQETSRRLREWEIKIKAEADEKAREIVSQAIQRCASDVVTETTTNVVPLPSDEMKGRLIGREGRNIRALEQATGVDLIIDDTPEAVTISSFDPVRREIARQALSKLIIDGRIHPARIEEVVAKAKEEVEAAMIASGEQAAYQAGVHGLRPEIIKVMGRLKYRTSYGQNVLQHSIEVAQMSGMIGSELGVNVTLARRAGFLHDIGKAVDRDVEGTHTQIGADMVKQWEKSPEVIKGVAEHHFDTPTVSIWGFIVSAADAISSARPGARRESLENYIKRLKALEEIADSFKGVEKSFAIQAGREVRIMVKPEEIDDLGAMRLARDIVKKIEDGLEYPGQIKVTVIRETRSVDFAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FRSA_VIBC3
Sequence: MSEASSKNLSETLFQNHKQAKETSSLTQYMPSSLELLDTRREQSSQAWYRNLRRLQWIWQGVDPVEQEEILARIASSKHSRTHDEWLDTVMGYRSGNWTYEWTRVGMLHQKQAAERQGEEAADQMFAAALYYSIAGYPHLRNDNLALQAQVLANNAYQEAAKLTGFVVKRLEFSYQNKKIAGYLHLRNTDSPKPVVLVSAGLDSLQTDMWRLFRDYLAKRDIAMLTIDMPSLGASSHWPLTEDSSCLHQAVLNQLADLPWVDHFRIGLIGFRFGGNAMARLAFLESDKVKACVSLGAPIHDIFTSPNKLAAMPKMYLDVLASRLGKNVVDVRSLSGQLMAWSLKVQGFMSGRRTKTPILALGLEGDPVSPYSDNQLVALFSQGGQAKKVKSKTISQGYEQSLDLAINWLEDELCK
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: HGD_PSEPU
Sequence: MTRDTSPDLHYLSGFGNEFASEALPGALPVGQNSPQRAPYGLYAELLSGTAFTMARSELRRTWLYRIRPSALHPRFERLARQPLTAPLGAINPNRLRWSPQPIPAEPTDFIEGWLPMVANAPAQKPAGVSIYIYCANRSMERVFFNADGELLLVPEQGRLRIATELGVMEVGPLEIAVIPRGMKFRVELLDGQARGYIAENHGAPLRIPELGPIGSNGLANPRDFLTPVAHYEEAEGPVQLVQKFLGEHWACELQHSPLDVVAWHGSNVPYKYDLRRFNTIGTVSFDHPDPSIFTVLTSPTSVHGLANMDFVIFPPRWMVAENTFRPPWFHRNLMNEFMGLISGAYDAKAEGFLPGGASLHGVMSAHGPDAETCEKAIAADLAPHKIDNTMAFMFETSQVLRPSQQALECPQLQADYDSCWATLPSTFNPNRR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of 2,5-dihydroxyphenylacetate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.