PharMolix/UniProtQA huggingface dataset:
Protein: CEP63_HUMAN
Sequence: MEALLEGIQNRGHGGGFLTSCEAELQELMKQIDIMVAHKKSEWEGRTHALETCLKIREQELKSLRSQLDVTHKEVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAVEAIRPREESLAEKKYTSQGQGDLDSVLSQLNFTHTSEDLLQAEVTCLEGSLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQSYSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRLRAEMQKAEDKAVEHKEILDQLESLKLENRHLSEMVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMNTKSQLEISTQMCKKQNDRIFKPTHSRTTEFKNTEFKPTHGQHRHDGIKTEHYKTDLHSPRGQASDSINPMSRVLSPLSPQISPCSSTRSLTSYSLCKTHSLPSALDTNEANFSDTMSESMNDQEEFISSCSLPVSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVRQFTALK
What is the function of this protein?
Required for normal spindle assembly (PubMed:21406398, PubMed:21983783, PubMed:26297806, PubMed:35793002).  Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:21983783, PubMed:26297806).  Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned (PubMed:21983783, PubMed:26297806).  Also recruits CDK1 to centrosomes (PubMed:21406398).  Plays a role in DNA damage response (PubMed:21406398).  Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (PubMed:21406398).  Promotes stabilization of FXR1 protein by inhibiting FXR1 ubiquitination (PubMed:35989368).
What are the official names of this protein?
Centrosomal protein of 63 kDa, Cep63.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
Protein: DCPS_BOVIN
Sequence: MAELAHQQSKRKRELDAEEAEASSTEGEEAGVGNGTSAPVRLPFSGFRVKKVLRESARDKIIFLHGKVNEASGDGDGEDAVVILEKTPFQVDQVAQLLKGSPELQLQFSNDVYSTYHLFPPRQLSDVKTTVVYPATEKHLQKYLRQDLHLVRETGSDYRNVTLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIKSLRDLTAEHLPLLRNILREGQEAILRRYQVAADRLRVYLHYLPSYYHLHVHFTALGFEAPGAGVERAHLLAEVIDNLEQDPEHYQRRTLTFALRADDPLLALLQEAQRS
What is the function of this protein?
Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by 3'->5' exosome-mediated mRNA decay pathway.  Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP).  Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency.  Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides.  Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) to m7GMP.  May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP.  Binds to m7GpppG and strongly to m7GDP.  Plays a role in first intron splicing of pre-mRNAs.  Inhibits activation-induced cell death.
What are the official names of this protein?
m7GpppX diphosphatase, DCS-1, Decapping scavenger enzyme, Hint-related 7meGMP-directed hydrolase, Histidine triad nucleotide-binding protein 5, Histidine triad protein member 5, HINT-5, Scavenger mRNA-decapping enzyme DcpS.
What is the protein family that this protein belongs to?
Belongs to the HIT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localized in the nucleus. Nucleocytoplasmic shuttling protein that can transiently enter the cytoplasm in mammalian cells in a XPO1/CRM1-dependent manner.
Protein: GVPC_SPICC
Sequence: ALQDDWQQSHLERRQVLAESQKQIQATIGALXXERQXXA
What is the function of this protein?
May confer stability to the gas vesicle membranes.  Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.
What are the official names of this protein?
Gas vesicle protein C.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type C family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Binds to the external surface of the gas vesicle membrane.
Protein: 88F1G_MALDO
Sequence: MGDVIVLYASPGMGHIVSMVELGKFIVHRYGPHKFSITILYTCGSIVDTASIPVYIRRISHSHPFISFRQFPRVTNNITRNISVPAITFDFIRQNDPHVRSALQEISKSATVRAFIIDLFCTSALPIGKEFNIPTYYFCTSGAAILAAFLYLPKIDEQTKTTESFKDLRDTVFEFPGWKSPLKATHMVQLVLDRNDPAYSDMIYFCSHLPKSNGIIVNTFEELEPPSVLQAIAGGLCVPDGPTPPVYYVGPLIEEEKELSKDADAAEKEDCLSWLDKQPSRSVLFLCFGSMGSFPAAQLKEIANGLEASGQRFLWVVKKPPVEEKSKQVHGVDDFDLKGVLPEGFLERTADRGMVVKSWAPQVVVLKKESVGGFVTHCGWNSVLEAVVAGVPMIAWPLYAEQHMNRNVLVTDMEIAIGVEQRDEEGGFVSGEEVERRVRELMESEGGRVLRERCKKLGEMASAALGETGSSTRNLVNFVSSIT
What is the function of this protein?
Glycosyltransferase that possesses phloretin 2'-O-glycosyltransferase activity.  Converts phloretin to phlorizin (phloretin 2'-O-glucoside), a potent antioxidant.  Is specific for phloretin and does not possess glycosyltransferase activity toward caffeic acid, catechin, chlorogenic acid, 2-coumaric acid, 3-coumaric acid, 4-coumaric acid, cyanidin, 3,4-dihydroxyhydrocinnamic acid, epicatechin, 3-hydroxybenzoic acid, naringenin, 3,4-dihydroxybenzoic acid, quercetin and rutin.  Can glycosylate phloretin in the presence of UDP-glucose, UDP-xylose and UDP-galactose.
What are the official names of this protein?
Phloretin 2'-O-glucosyltransferase, Phloretin glucosyltransferase 1, MdPGT1, UDP-glucose:phloretin 2'-O-glucosyltransferase, UDP-glycosyltransferase 88F1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: NUOD_TRIL1
Sequence: MANNEIMTINMGPQHPSTHGVLRMVIELDGETILKIDPDIGYLHRGVEKLSEHRTYHQTLPLTDRLDYLAPMSNNLGYMLAVEKLLGIEVPERAQTIRIIMTELTRLQSHLVWLACHALDIGAMTVFIYAFREREVIMETYELISGARMTSNFFRAGGLSQDVPAEFEKKVRDFVAEMPGFIDTYEGLLTGNPIWRKRTIGNGVISAEDATDIGITGPALRGSGVDFDLRRDIPYAGYENYQFKVPTGKNCDTFDRYQVRLIEMRESCKIVNQALERLKPGPVLADAPQVCYPPKDSVYNSIEGLIHHFKIASEGYPVPEGEVYMGVEAPKGELGFYLVSDGSSKPYRMRVRPPSFVNLQAIEKMAKGAMLADLVAIIGTLDIVLGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CPXA_ECO57
Sequence: MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQRQGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEMQIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLLFDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEFLAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELERIETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLYKRS
What is the function of this protein?
This protein is involved in several diverse cellular processes, such as the functioning of acetohydroxyacid synthetase I, in the biosynthesis of isoleucine and valine, the TraJ protein activation activity for tra gene expression in F plasmid, and the synthesis, translocation, or stability of cell envelope proteins.  Activates CpxR by phosphorylation (By similarity).
What are the official names of this protein?
Sensor protein CpxA.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARRB_CALVI
Sequence: MVVSVKVFKKATPNGKVTFYLGRRHFIDHFDYIDPVDGVIVVDPDYLKNRKVFAQLATIYRYGREEDEVMGVKFSKELILCREQIVPMGNSNMEMTPTQEKLVRKLGSNAHPFTFHFPPNSPSSVTLQQEGDDLGKPLGVEYTIRAYVADSEDDRQHKRSMVSLVIKKLQYAPPTRGQRLPSSLVSKGFTFSNGKISLEVTLDREIYYHGGKVAATVQINNNSKKAVKNIKVFIIQHTEITMVNAQFSKHVAQLETKEGCPITPGANLSKTFYLIPLASNNKDRHGIALDGHLKDEDVNLASSTMVQDGKSTGDACGIVISYSVRIKLNCGTLGGEIQTDVPFKLLQPAPGSVEKKRSNAMKKMKSIEQHRNTKGYYQDDDDNIVFEDFAKMRNNNADVMD
What is the function of this protein?
Directly interacts with light-activated rhodopsin thereby activating the phosphorylation of metarhodopsin.  Inhibits the dephosphorylation of metarhodopsin.
What are the official names of this protein?
Phosrestin-1, Arrestin-2, Arrestin-B, Phosrestin I.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: IHH_RASEL
Sequence: VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.
What are the official names of this protein?
Indian hedgehog protein, IHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Cell membrane. Secreted, extracellular space. Note=Indian hedgehog protein N- product: Cell membrane; Lipid-anchor; Extracellular side. The N- terminal peptide remains associated with the cell surface. Indian hedgehog protein C-product: Secreted, extracellular space. The C- terminal peptide diffuses from the cell.
Protein: RL6_STAAS
Sequence: MSRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGKGIRYQGEYVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RIMP_CAUSK
Sequence: MRGKTQEDIGLVELLDPVAESVGYEIVRLRLMGGAEQRRLQIMAERPDGDMNVEDCAKLSRAISEILDAADPISGEYTLEVSSPGVDRPLTRLKDFETYAGLEVRIELDRVAEGRKRFKGELAGVEDGQVGLNLEGEDDTTVYFPFEWIVDAKLVLTDQLMKRGAEQRAARVGAEGEDANEDLGDDAEDDIDLSESEED
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDZ_ECO24
Sequence: MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLAKLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELAAESPLMMIMLNALSKRIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSRELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHETWNLDTFLRYPHISICWEQSDTWALDNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPLPFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRETIKNLYASMA
What is the function of this protein?
Involved in anaerobic NO protection.
What are the official names of this protein?
HTH-type transcriptional regulator YidZ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: YTFB_ECOLI
Sequence: MPGRFELKPTLEKVWHAPDNFRFMDPLPPMHRRGIIIAAIVLVVGFLLPSDDTPNAPVVTREAQLDIQSQSQPPTEEQLRAQLVTPQNDPDQVAPVAPEPIQEGQPEEQPQTTQTQPFQPDSGIDNQWRSYRVEPGKTMAQLFRDHGLPATDVYAMAQVEGAGKPLSNLQNGQMVKIRQNASGVVTGLTIDTGNNQQVLFTRQPDGSFIRAR
What is the function of this protein?
Cell division protein whose function is related to the generation of a transient cell wall structure.  Function is linked to the late stages of cell division.
What are the official names of this protein?
Cell division protein YtfB.
What is the protein family that this protein belongs to?
Belongs to the OapA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=Localizes to the septal ring prior to the onset of constriction and remains at the midcell throughout cytokinesis. Recruitment to the septal ring requires FtsZ, but not downstream division proteins.
Protein: RRF_ACHLI
Sequence: MNEQADMILLEIEEKMEKSLEALGREYAAVRTGRANPNILDRIMVSYYGVDTPLKQVASISVPEAQQLYIKPFDKSILKDIETAINTSSLELPPRNDGTGIRLTLPALTGERRRSLVKDVEKMAEAGKVAIRHIRRDGNEHLKKLGLTEDDEKGYLEDVQALTDAYVKKVDELTKEKSEELLDV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHD_MYCSK
Sequence: MTSIDWRSALTDDEQGSIRDIVAAATRHDGVAPVGDQVLRELPADRTRHLVAVDPDAGAVVGYLNLAPASDTAPPMAELVVHPDFRRRGTGAAMARAGLAEGGTHARIWAHGNLEAARATARTLGLQVVRELLQMRRPLTDLPPVTVADGVRLATYSGPGDDPELLRINNSAFAWHPEQGGWTDADIAERRAEAWFDPAGLFMAFDDASGKLLGFHWTKVHGPDLGEVYVVGVDPAAQGRGLGATLTLTGLHHLAERLSNSPQPTVMLYVEADNGAAVKTYRRLGFDVSSVDAAYAAVAD
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: MGSA_ALIF1
Sequence: MNKTTRVMPAHKHIALVAHDNYKPELLRWVKENKDALQGHFLYATGTTGRILSKETGLAIKSLLSGPMGGDQQLGALISEGKIDMMIFFWDPLNAVPHDPDVKALLRIATVWNVPVAMNRASAKFMISAPQMEEEVSIEIPDYDAYLAERV
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RRT4_ARATH
Sequence: MEVRSESNITQARSDKLPLPPAVPKPRVQVWFVRVCSSILVWTCLVQLFAAGELWHSRIFTGLTNQISRFSAPVEPVPLPPPLPPPRNYTSNGILLVSCNGGLNQMRSAICDMVTVARLLNLTLVVPELDKTSFWADPSGFEDIFDVRHFIDSLRDEVRILRRLPKRFSRKYGYQMFEMPPVSWSDEKYYLKQVLPLFSKHKVVHFNRTDTRLANNGLPLSLQWLRCRVNFQGLKFTPQLEALGSKLVRILQQRGPFVALHLRYEMDMLAFSGCTHGCTEEEAEELKKMRYTYPWWREKEIVSEERRAQGLCPLTPEEVALVLKALGFEKNTQIYIAAGEIYGSEHRLSVLREAFPRIVKKEMLLESAELQQFQNHSSQMAALDFMVSVASNTFIPTYDGNMAKVVEGHRRYLGYKKTILLDRKRLVELLDLHHNKTLTWDQFAVAVKEAHERRAGAPTHRRVISDKPKEEDYFYANPQECLCEGTNCHDLFGHRNLTH
What is the function of this protein?
Glycosyltransferase involved in the formation of rhamnogalacturonan I (RG-I) oligosaccharides in the seed coat mucilage, which is a specialized cell wall with abundant RG-I (By similarity).  Transfers the rhamnose residue from UDP-beta-L-rhamnose to RG-I oligosaccharides (PubMed:30082766).
What are the official names of this protein?
Rhamnogalacturonan I rhamnosyltransferase 1, O-fucosyltransferase 3, O-FucT-3, O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: SMOX1_SCHMA
Sequence: NSNNINLSYDDQQRLIYSGTEQKYPTSNQLKSYPNGLLNPFNGTNFMHPTIQSNSLITRHPNNNSFQLNTTNDSNNNNTTNNGNDSRSHLYDISTFNAQNPYSLTNTLNFNSRTMNNQLTMNDSMKLNGNLTLHDTNYHALLNGSTSFGSTVFRSLVNSENQSYLNSSTNMLMNSSLDNINNSNDHSTLNDNNNDCIGQSLRQSGNSSESNVVVYPWMNPKGTDISVDQKRTRQTYTRYQTLELEKEFHFNKYLTRRRRIEIAHTLTLTERQIKIWFQNR
What are the official names of this protein?
Homeobox protein SMOX-1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PXR1_AJECN
Sequence: MGLAGPRKRTKISHDPNNTAWSRSTSGYGHKIMSAQGWTPGSFLGASNAAHADHFTAGSAGHIRVILKDDNLGLGAKLRAEDEPTGLDAFQGLLGRLNGKSDEELEKELKKRHDRQLANFVEKRWKTMQFVSGGLLVHEKIQALADVKSAGGEEVQTPQISHDELKSEKRPKKARKKEKRRARGDDTGLDLAEQSPKRKRKDRKENKEKKKSSDDSSYANQGTPSEDALVDKIQKKRKKRKQKDPEPSNTEVHDDSLPPDTRSVSQEEQESRYSAKNESIRKIREHRPMGRQFTRGRHIQQKKLALMDSKSISEIFMVKC
What is the function of this protein?
Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.
What are the official names of this protein?
Protein PXR1, PinX1-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the PINX1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACCD_PROMS
Sequence: MSLIDWFAARRKDQFVGKVSQDTDEGDGLWVKCSECSQVAYRKDLISNFNVCNNCGHHNRINSDERINIIADKNSFKEFDSLLSPTDPLGFKDRRAYADRIKESQAGTGLRDGVVTGICSVNSMPLALAVMDFRFMGGSMGSVVGEKITRIIERATLENFPILIVCASGGARMQEGMLSLMQMAKISGALKKHKEKNLLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIEQTLREKLPDNFQTAEYLLEHGFVDVIVKRKDLKDTLTKILKIHGVKELAEANT
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TY4_ASCTR
Sequence: EPRTPWDWV
What is the function of this protein?
Putative defense peptide.
What are the official names of this protein?
Tryptophyllin-4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: METAA_CERS1
Sequence: MPITLPATLPAFDVLTHEGVMVMTPERAARQDIRPLRIGLLNLMPKKIQTENQFARLIGATPLQIDFQLIRMTEHQTKNTAAEHMEAFYRPFQEVKHEKFDGLIITGAPIEHLDFADVTYWDELCEVMDWTQTNVQSTFGVCWGGMAMIYHFHRVQKHRLQAKAFGCFRHRNVAPTSPYLRGFSDDFVIPVSRWTEMRQAEIDAAPGLRTLLASDEAGPCLVEDPGHRALYIFNHFEYDSDTLKQEYDRDVANGKPINVPANYYPDDDPSKPPLNRWRSHAHLLYGNWINEIYQSTPYDPQQIGR
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLNK_HUMAN
Sequence: MNRQGNRKTTKEGSNDLKFQNFSLPKNRSWPRINSATGQYQRMNKPLLDWERNFAAVLDGAKGHSDDDYDDPELRMEETWQSIKILPARPIKESEYADTHYFKVAMDTPLPLDTRTSISIGQPTWNTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLPPPRPLITLPKKYQPLPPEPESSRPPLSQRHTFPEVQRMPSQISLRDLSEVLEAEKVPHNQRKPESTHLLENQNTQEIPLAISSSSFTTSNHSVQNRDHRGGMQPCSPQRCQPPASCSPHENILPYKYTSWRPPFPKRSDRKDVQHNEWYIGEYSRQAVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFPIILIDGKDKTGVHRKQCHLTQPLPLTRHLLPL
What is the function of this protein?
An adapter protein which plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation (By similarity).  Together with FGR, it acts as a negative regulator of natural killer cell-activating receptors and inhibits interferon-gamma production (By similarity).  Acts as a positive regulator of both T-cell receptor and natural killer T (NKT) cell receptor signaling in CD4-positive NKT cells (By similarity).  Together with MAP4K1, it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity).  May be involved in tumor necrosis factor induced cell death by promoting reactive oxidative species generation, and MLKL oligomerization, ultimately leading to necrosis (By similarity).  Involved in phosphorylation of LAT (By similarity).  May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells (By similarity).
What are the official names of this protein?
Cytokine-dependent hematopoietic cell linker, Mast cell immunoreceptor signal transducer.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_STRA1
Sequence: MNTLIVNSHPDFSNPYSFTTILQEKFIELYNEHFPNHQLSILNLYDCVLPEITKEVLLSIWSKQRKGLELTADEIVQAKISKDLLEQFKSHHRIVFVSPMHNYNVTARAKTYIDNIFIAGETFKYTENGSVGLMTDDYRLLMLESAGSIYSKGQYSPYEFPVHYLKAIFKDFMAFDDFCVVRAEGTDILDRQVVLDKMNQDLREAFEAFYSKE
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RS11_METS4
Sequence: MAKEATRIRRRERKNIVSGVAHVNASFNNTMITITDAQGNTISWSSAGAMGFKGSRKSTPYAAQVAAEDAGRKAAEHGMRTLEVEVSGPGSGRESALRALQAAGFTVTSIRDVTPIPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MUTL_RICPU
Sequence: MTIKFLSESTINRIAAGEVIERPASVVKELVENAVDASSTKIDIILERAGKNLIIISDDGIGMTDKELEIAVERHTTSKFDESDFLNINTFGFRGEALPSIAAISKMLITSKKRDADKAFQIKLIGGNEKQVTISVHNEGTKIEIRDLFFATPARLKFLRADKTELAATVGVVKKIALAHPKISLSLTHDGKNLLKLKGQNKDAETNLKQRIIDVIGDDFIKNAAYIDFKTPDFSICGYTSSPTYNRASSEDQFLFINNRPVKDKLLQVALRVAYQDYLARDRYPICAIFLQINPQLVDVNVHPAKAEVRFHDPNYVRNLLIEAIKNALTNKSHVTSTTIASDALELFKNPLVNKQSPVSKVINVNSKSADYRPTTHSTLNTVPQNHVCQKLIDTLSHAKIEQEVENHIEHEQQTRKQYKLGAAKAQLHTTYIISQTEDSIVITDQHAAHERLGYEKIKDYLKTEELIKQRLLIPEIVELPNEKKADCLYDHREKLYKLGLTLEKFGEKSIIVTEIPNILGDVNVQKLIQDLADHLSDFGKNIALTELIEHVTETYACHYSIRAGRKLSADEMNALLRQMENTPLSGQCNHGRPTYIELKLKDIERLFGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.