PharMolix/UniProtQA huggingface dataset:
Protein: MUTS_SYNSC
Sequence: MPRSASQPPDDALQGNLFGAPEPAAPSATATASEPETASHDLSDDELGADAAARPRTRQATASEGSSEAPAANDSEPSRDEPAWGHHSQLDPLQLTPMLRHYVELKAAHPERVLLYRLGDFFECFFEDAIELSRVLELTLTGKEGGKAIGRVPMAGIPHHAAERYCAELIKQGYSVALCDQLETTPTKGALLKRDITRVLTPGTVLEEGMLSARRNNWLAAVVVEPAQGKQPLRWGLASADVSTGEVQVMQREDSSALHQQLAQQEASELLWAAALDTERPAWCPERLRLTPMASTPFSPVEAERTLQQHYGLSSLDGLGLPEHPLALQALGGLLGYLQDTQPLEEDSRIPLEVPAIVHRGDALVLDAQTRRNLELTATQRDNQLQGSLLWAIDRTLTAMGGRCLRRWLEAPLMDRQAIQQRQDLVSSLVGERSLRLAIRQLLRPMGDLERLAGRAGAGHAGARDLVAIADGLERLPQLTARLKSAISTGPEWLQQLLSPDPALAELARTIRHKLVEAPPLSLSEGDLIHDGVDPLLDGLRNQLDDQDAWLSHQEQQERQRCGISTLKLQHHRTFGYFLAVSKAKATAVPEHWIRRQTLANEERFITPDLKEREGRIFQLRARACQREYELFCQLREQVGAMAAPIRQAARAVAALDALTGLGDVAASGGYCAPTITDGRGLQLEDSRHPVVEQRLVETAFTPNDVQLGEGTDLVVLTGPNASGKSCYLRQIGLIQLMAQIGSWVPARSATVGIADRIFTRVGAVDDLAAGQSTFMVEMAETANILHHASDRSLVLLDEIGRGTATFDGLSIAWAVSEHLAGDLGSRTVFATHYHELNNLAAERDNVANFQVLVEETGEDLVFLHQVQAGGASRSYGIEAARLAGVPKPVVQRARQVLDQLTA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: SDHD_VIBCH
Sequence: MMTINIEQLTEQYPLVKELIELKEVSWFNPSITRLEEGLSYVGLGSEDIQDASQRLKRFAPYLAKAFPETAKTNGIIESEVVPISEMQSVLEREYDTPIQGRLLLKKDSHLPISGSIKARGGIYEVLTHAEKLAIEAGLLTESDDYSKLLNEEFRDFFKRFSIAVGSTGNLGMSIGIMSAKLGFSVSVHMSADARAWKKNRLRALGVNVIEYAQDYGVAVAQGRKEAENDPTCFFIDDENSQTLFLGYSVAGERLKKQFDEKGIVVDAQHPLFVYLPCGVGGGPGGVAFGLKMAFGDNVHCIFAEPTHSPCMMLGVHTGLHDAISVQDIGIDNITAADGLAVGRASGFVGRAMERLLDGYLTISDERMYRLLGQLNEAENIQLEPSALAGMIGPIVVTKSVEYRARMQFDDTVMGNATHLVWATGGGMVPAEEMDSYLKNR
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: MSRA_PSECP
Sequence: MKTFVLGGGCFWCLDAVYQKTKGVTAVVSGYTGGHDPYPDYYSVCSGTTGHAEVVAVTFDEEIIPAEVILDMFFALHDPTTLNRQGYDVGTQYRSSMFYETTEEKILFEEAIDRNQALWSHPIVTEVSRLPRFHVAEEFHQDYYAKHPEQGYCQVIINPKLAKARKYYSAWLNA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: KUP3_CUPNH
Sequence: MTQSATAHYFVESPSTGALVLGAVGVVFGDIGTSPLYALKECFSKEHGIAFSPDAVLGVISILFWAMIIVVSIKYVVFVMRADNDGEGGVLALMALVLRTVAQRSRKAKILMMLGIFGACMFYGDAVITPAISVLSAVEGLEIAAPQLSQFVIPITLVILAALFLIQRHGTAAVGKLFGPIMTTWFVALGALGILNLVQAPEILKSINPYYAISFLVEHALQAFIVLGSVFLVLTGAEALYVDMGHFGARPIRIGWFVLVMPCLILNYFGQGAMLLHNPAGVENPFFLMVPELLQLPMVLLATSATVIASQAVISGAFSLTSQAIQLGFVPRMRVLYTSAAEIGQIYLPVVNWLLLVLVIGVVISFKKSENLAAAYGIAVTTTMVITTFLAAVCMRNVWKWDPALVAVLGTSFLLVDLAFFAANLLKIAEGGWFPLLLGSAAFFMLMTWYSGRKLLRARSLEDGIPLEPFIAGLLAHPPHRVEGTAVFLTGSIDTVPVSLLHNLKHNRVLHERVVFLTFVTRDIPYVDDDQRVSCKDLGGGAFILKSEYGFKETPDVQKVLDLADRKLGMHFELMETSFFIARESVIPSRLPGMPMWRESLFAWMHQNGAKPSDFFQIPANRVVELGTKVEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 3.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HXA10_HETFR
Sequence: MSGMEVWSDPPRSCRMEQPATQQVATCSFPQNIKEENAYCLYDSEKCPKSAAATDLSTFPRLTSESCSNNDTTTSGGVPVPGYFRLSQAYPTSKQTLYSNTGQVGASPFVPQSQIRFGTPPSSASTPTELGRKGSEGTSPGHLTCSSEREEAEAAASSANEESSPVPSESNKNSPEKETKGEVKAENGANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFSFS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A10.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFG2_BORBR
Sequence: MTRRTSIERYRNIGISAHIDAGKTTTTERILFYTGITHKLGEVHEGAATMDWMEQEQERGITITSAATTAFWRGMAGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYDSVGGVQPQSETVWRQANKYGVPRIAFVNKMDRVGADFFRVQRQIVERLKGDAVPIQIPVGAEDHFEGVVDLVKMKAIIWDDASQGVRFEYRDIPPELQAQAEQWREKMIEKAAEANEALLEKYLSGQPLSEDEIKSGLRARTVANEIVPMLCGSAFKNKGVQAMLDAVIDYLPSPADVPAIIGHDERDREIERHPADDEPFSALAFKIMTDPFVGQLVFFRVYSGVVKSGDSVLNPLKSKKERLGRILQMHANERREISEVYAGDIAAAVGIKEITTGDTLTDPAHVIILERMTFPEPVISQAVEPRTKADQEKMGIALNRLAQEDPSFRVRTDEESGQTIISGMGELHLEILVDRMKREFGVEANVGKPQVAYRETIRSTVTDVEGKFVKQSGGRGQYGHVVLKLEPQEQGKGYEFVDAIKGGVVPREFIPAVDRGVRETLNTGVLAGYPVVDVKVTLVFGSYHDVDSNENAFRMAASMAFKEGMRRAKPVLLEPMMHVEVETPEDFTGNVMGDLSSRRGMVQGMEDIAGGGGKLVRAEVPLAEMFGYSTSLRSLTQGRATYSMEFKHYAEAPRQVAEQIIAARGSGAAARG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYNA1_THEST
Sequence: MKRKVKKMAAMATSIIMAIMIILHSIPVLAGRIIYDNETGTHGGYDYELWKDYGNTIMELNDGGTFSCQWSNIGNALFRKGRKFNSDKTYQELGDIVVEYGCDYNPNGNSYLCVYGWTRNPLVEYYIVESWGSWRPPGATPKGTITVDGGTYEIYETTRVNQPSIDGTATFQQYWSVRTSKRTSGTISVTEHFKQWERMGMRMGKMYEVALTVEGYQSSGYANVYKNEIRIGANPTPAPSQSPIRRDAFSIIEAEEYNSTNSSTLQVIGTPNNGRGIGYIENGNTVTYSNIDFGSGATGFSATVATEVNTSIQIRSDSPTGTLLGTLYVSSTGSWNTYQTVSTNISKITGVHDIVLVFSGPVNVDNFIFSRSSPVPAPGDNTRDAYSIIQAEDYDSSYGPNLQIFSLPGGGSAIGYIENGYSTTYNNVNFANGLSSITARVATQISTSIQVRAGGATGTLLGTIYVPSTNSWDSYQNVTANLSNITGVHDITLVFSGPVNVDYFVFTPANVNSGPTSPVGGTRSAFSNIQAEDYDSSYGPNLQIFSLPGGGSAIGYIENGYSTTYKNIDFGDGATSVTARVATQNATTIQVRLGSPSGTLLGTIYVGSTGSFDTYRDVSATISNTAGVKDIVLVFSGPVNVDWFVFSKSGT
What is the function of this protein?
Endoxylanase that degrades arabinoxylan and glucuronoxylan to xylobiose and xylotriose (in vitro).
What are the official names of this protein?
Endo-1,4-beta-xylanase A, 1,4-beta-D-xylan xylanohydrolase A, Xylanase 11A, Xyn11A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYD_PYRAB
Sequence: MLRTHYSSEITEELNGKKVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVPQEIFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEIIPEKLEVISKAKTPLPLDPTGKVKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGGTELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDAEMAFIESEEEVMDLLERLILYVINYVRENNEKELKILEFELNEPKKPFPRITYDEALEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPEVCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGLGAERLIMRMLDIGNIREVILFPRDRRRLVP
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA(Asp) ligase, Aspartyl-tRNA synthetase, AspRS, Discriminating aspartyl-tRNA synthetase, D-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM64_MOUSE
Sequence: MRNPGGSLPHTLPRALQHAGRTGVVEQPGRWAPERTAGGDRSEDRLPRGGGASAAAAAAAAAASGALLGAYLERHGLPAASDLPAPAGALAGGPGSGGGVVVGVAEVRNWRCCCLGSTCWCRSLVLVCVLAALCFASLALVRRYLQHLLLWVESLDSLLGVLLFVVGFIVVSFPCGWGYIVLNVAAGYLYGFVLGMGLMVVGVLIGTFIAHVVCKRLLTAWVAARIQNSDKLSAVIRVVEGGSGLKVVALARLTPIPFGLQNAVFSITDVPLPSYLMASSAGLLPTQLLNSYLGTTLRTMEDVIAEQSLSGYFVFCLQIVISIGLMFYVVHRAQVELNAAIVACEMELKTSLVKGNQSDPSGSSFYNKRTLTFSGGGINIV
What is the function of this protein?
Positively regulates TNFSF11-induced osteoclast differentiation.  Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with SERCA2 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation.  Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca (2+) spiking for activation of NFATC1 and production of mitochondrial ROS, thereby triggering Ca (2+) signaling cascades that promote osteoclast differentiation and activation (PubMed:23395171).  Negatively regulates osteoblast differentiation and positively regulates adipocyte differentiation via modulation of the canonical Wnt signaling pathway.  Mediates the switch in lineage commitment to osteogenesis rather than to adipogenesis in mesenchymal stem cells by negatively regulating the expression, activity and nuclear localization of CTNNB1 (PubMed:25979161).
What are the official names of this protein?
Transmembrane protein 64.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: RIMM_LEUCK
Sequence: MTKENYFKVGTIVNTHGIRGEVKIMAITDFAADRFKKGAALQIETKQGFVPVTVQSSRLHKNMWLVLFEGVTNINEIEKYKTNDIYVYGEAREALGDDEYYYDEIIDSRVVSLSGEAIGVVSEIMTTGANDVWVVKRPGQSDALIPMIDDVVKSVDVANKLITIDVLEGLLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC75_ARATH
Sequence: MNKSNPAGSVTGSDIIDAKIEEHQLCGSKKCPSCGHKLEGKPQDWVGLPAGVKFDPTDQELIEHLEAKVLAKDFKSHPLIDEFIPTIEGEDGICYTHPEKLPGVTRDGLSRHFFHRPSKAYTTGTRKRRKIQTECDNNLQGSSSSGETRWHKTGKTRPVMVNGKQKGCKKILVLYTNFGKNRKPEKTNWVMHQYHLGTHEEEKEGELVVSKIFYQTQPRQCNWSSSTSSLNAIGGGGGEASSGGGGGEYHMRRDSGTTSGGSCSSSREIINVNPPNRSDEIGGVGGGVMAVAAAAAAVAAGLPSYAMDQLSFVPFMKSFDEVARRETPQTGHATCEDVMAEQHRHRHQPSSSTSHHMAHDHHHHHHQQQQQRHHAFNISQPTHPISTIISPSTSLHHASINILDDNPYHVHRILLPNENYQTQQQLRQEGEEEHNDGKMGGRSASGLEELIMGCTSSTTHHDVKDGSSSMGNQQEAEWLKYSTFWPAPDSSDNQDHHG
What is the function of this protein?
Transcription activator involved in xylem formation (PubMed:25265867, PubMed:25535195).  Promotes the expression of the secondary wall-associated transcription factor MYB46 (PubMed:25265867).  Functions upstream of NAC030/VND7, a master switch of xylem vessel differentiation (PubMed:25265867, PubMed:25535195).  Acts as upstream regulator of NAC101/VND6 and LBD30/ASL19 (PubMed:25535195).
What are the official names of this protein?
NAC domain-containing protein 75, ANAC075.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPN2_BOVIN
Sequence: MAGAAPTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLGDVMDALQLGPNGGLLYCMEYLEANLDWLRAKLDPLRGHYFLFDCPGQVELCTHHGALRSIFSQMTQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHVNLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQQVLQAVDKANGYCFGVQEQRSLEAMMSAAMGADFHFSSTLGLQEKYLAPSEQSVEQEAMQL
What is the function of this protein?
Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 2, ATP-binding domain 1 family member B.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: IF1C_PHYPA
Sequence: MKKQNLIDMEGVVTESLPNAMFRVCLDNGCEVLTHISGKIRRNYIRILPGDRVKVELTPYDLTKGRITYRLRAKSSNS
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: QUEE_HAEIN
Sequence: MLMEKYHDFEPNFNIVEIFESLQGEGFNTGMPSVFVRFGKCNLDCPWCDTPYNNFKRWSVSQILEKVRSFSSKNIIITGGEPTIVPKIEYLLEQFKSDGYFLAIETNGLKAIPAQIDYIATSPKSLYAHKYEKRCIPFANEVRIVMDSNMPSFCELIEQKIKAKNYYLSPCEIDGKMNLLETITLLGQLNQRSNKPKWQLSLQTHKLIGIE
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: TATA_RHOP5
Sequence: MGSLSIWHWLVVIVVVLLLFGRGKISDLMGDVAQGIKSFKKGLQDDDKTAEKTEPVKSIDHAAPPASAPRSDVGSKAV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MUTL_HALS3
Sequence: MTDRIRALDDATVARIAAGEVVERPASVVKELVENSLDAGAASVDVSVDAGGTDRIVVADDGRGMTGDDLRMAVRQHTTSKLDDASGLDGVGTLGFRGEALYTIGSVAELTVTTRPRNAGDTGARITVDHGDAGSVAPAGHPAGTTVEVTDLFGETPARRKYLKRAATEFGHVNRAVTRYALANPDVAVSLTHDGREVFATTGTGDVQDAALAVYGREVAQSLRTVDADPAADSVERVHGYVSDPEVTRSTREYLATFVNGRAVTDAVLREAVLDGYGDQLAPDRYPFAVLFVDCEGVDANVHPRKLEVRFEDEAGVKAAVEAGVRDALLDAGLVRAGAPRGASKPGDAEISPEHSPTDRDAGAAGGGDAAGQSDGNGQRTAASGATSESPASAFETGGGDEAADSAASTDGTRERPGSGTESRTGRFDAPAENARLPTGAGGPEADDQDTTSERDSLPDLRVLGQLHDTYVVAEAGDGLVLVDQHAADERVHYERLQARVDGASQALVAPAELELTAGEAAVFEAALGGLRELGFDAELAGRTARVTAVPAVLADALDAELARDVLSSFLADADGTPVADAADAVLADLACSPAIKGNTSLAEGSVVALLDALDACENPYACPHGRPTIVEVDGDELAARFERDYPGHAGRRREDAGN
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ISPE_BRUA2
Sequence: MTAFQNAGPSITRLAPAKINLALHVTGRRDDGYHLLDMLVVFADHGDRIHIEKAGSDSFTVSGPFASGIPAGRGNLVLKARDALRQHGGPDLSPVAIHLEKNLPIASGIGGGSSDAAATLLALNTLWQLDLDFEMLAAIGLSLGADLPMCLHGAAHGTPLIARGIGEELNDVSGIAALPMLLVNDGTALATPDVFRALTRRENAPLPPPACEGTDALCAYLRETRNDLLPAAISLAPQIEPKLALLRAKGALYAQMSGSGATCFAIFSDESALTRAAKEIADENPGWFAVPSHSFPSRA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CHH5_PENMO
Sequence: MSLGLIASRLVAVALVVVVACSTTWARSLEGSSSPVASLIRGRSLSKRANFDPSCAGVYDRELLGGLSRLCDDCYNVFREPKVATECRSNCFYNSVFVQCLEYLIPADLHEEYQAHVQTVGK
What is the function of this protein?
Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level.  Has a secretagogue action over the amylase released from the midgut gland.  May act as a stress hormone and may be involved in the control of molting and reproduction (By similarity).
What are the official names of this protein?
Crustacean hyperglycemic hormones 5, Pm-SGP-V.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: GL811_ORYSJ
Sequence: MASSSFLLLATLLAMASWQGMASDPSPLQDFCVADMHSPVLVNGFACLNPKDVNADHFFKAAMLDTPRKTNKVGSNVTLINVMQIPGLNTLGISIARIDYAPLGQNPPHTHPRATEILTVLEGTLYVGFVTSNPDNKFFSKVLNKGDVFVFPVGLIHFQFNPNPYKPAVAIAALSSQNPGAITIANAVFGSKPPISDDVLAKAFQVEKGTIDWLQAQFWENNHY
What is the function of this protein?
Plays role in broad-spectrum disease resistance.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 8-11.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: CH60_RUMCH
Sequence: MAKEIKFGEEARRSLEKGVNQLADTVKVTLGPKGRNVVLDKKFGSPLITNDGVTIAKEVELEDKFENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGMKNVAAGANPMILKKGLQKAVDTAVAGIKENSRKVKGKEDIARVATISANEELIGTLIADAMEKVTNDGVITVEESKTMGTNLEVVEGMQFDRGYLSAYMVTDTDKMEAVLDDPYILITDKKLTNIQDLLPILEEIVKQGKKLLIIAEDIEGEALTTLILNKLRGTFVCVAVKAPGFGDRRKAMLQDIAILTGGEVITEELGLDLKETQITQLGKARQVIVQKENTIIVDGNGSAEDIKSRINSIKTQIEDTTSDFDREKLQERLAKLSGGVAVIQVGAATETEMKEKKLRIEDALAATRAAVEEGIVAGGGTAFINVIPEVAKLLESTSGDEKTGVQIILRALEEPVRQIAENAGLEGSVIVEKIKTSEKGMGFDALNEKYIDMIEGGIVDPAKVTRSALQNAVSVAAMVLTTESVVADKPEPEAPAVPAGMPGGMGGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPPJ_MYCBO
Sequence: MPHSTADRRLRLTRQALLAAAVAPLLAGCALVMHKPHSAGSSNPWDDSAHPLTDDQAMAQVVEPAKQIVAAADLQAVRAGFSFTSCNDQGDPPYQGTVRMAFLLQGDHDAYFQHVRAAMLSHGWIDGPPPGQYFHGITLHKNGVTANMSLALDHSYGEMILDGECRNTTDHHHDDETTNITNQLVQP
What are the official names of this protein?
Putative lipoprotein LppJ.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ACCA_RHOP5
Sequence: MPDPMRSYLDFEKPVAELDSKIDELHALAAGGSNIGEEIAKIEEKALAALTELYAALTPWQKTQVARHPQRPHCVDYIEGLITEFTPLAGDRKFGEDEALIGGFGRFRGESVCVLGQEKGFSTETRLKHNFGMARPEGYRKAVRLMEMADRFGLPVLSLVDTAGAYPGIGAEERGQAEAIARSTEACLKLGVPNVAVVIGEGGSGGAIAIATANKVLMLEHAIYSVISPEAASSILWRDSSKAQEAATSMKITAQDLLRFGVIDQILTEPRGGAHRDSAAMIAKAGDAIAKSFADLSSLDSDAIRAQRRQKFLDIGRKLG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_PELPB
Sequence: MRIELLNTPPDASETRIEEQIRPLRMDAFAGQQRLTDNLRVFISAAKMRGEALDHVLLSGPPGLGKTTLAYIIASEMGSSIKSTSGPLLDKAGNLAGLLTGLQKGDVLFIDEIHRMPPTVEEYLYSAMEDFRIDIMLDSGPSARAVQLRIEPFTLVGATTRSGLLTSPLRARFGINSRFDYYAPELLEGIIRRASTILGIGIDAEAASEIAGRSRGTPRIANRLLRRARDFAQVDGESFISRSIAMKTLDCLEIDEEGLDDMDKKIMETIVNKFNGGPVGIASLAVSVGEEQDTIEEVYEPYLIQAGYLTRTTRGRVATRQALIRFSTASERDEISLFDAQPTS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: KPRS3_ORYSJ
Sequence: MATAASASASASPAAAFGAKTRRPGPSPSPSPSPASAFARPSPRASAAGRLHASLHLGGASATGSSIVSNASGIHLAAPVLAPLAVPKMTGAVGAHKNVLLFHCEEMRELAEQVVARNDDIELRSISWRTFADGFPNLFISNAHTIRGQHVAFLASFSSPSVIFEQLSIIYALPKLFISSFTLILPFFPTGTSERMEDEGDVATAFTLARILSNIPISRGGPSSLVIFDIHALQERFYFGDSVLPCFESGIPLLKSRLQELPDSDNITIAFPDDGAWKRFYKQLQHFPMVVCNKVREGEQRIVRIKEGDPRGRHVVIVDDLVQSGGTLIECQKVLAEHGAAKVSAYVTHGIFPNKSWEKFQPDNGEGPGHGLSHFWITDSCPLTVNAVKDRQPFEILSLAGPIASALQI
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 3, chloroplastic, Phosphoribosyl pyrophosphate synthase 3.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.