PharMolix/UniProtQA huggingface dataset:
Protein: RLME_DICNV
Sequence: MARSKSSGRWLKEHHSDVFVLKAREEGFRSRAVYKLKEIQEKDRIIRPNMTVVELGAAPGGWSQYVAGILNGRGRMIALDILPMDALPDVHFIQGDFREETVLNALYDIIGEGNYVDLVISDMAPNTSGIKSVDQARSMHLVELAADFAQERLVAGGDFLCKVFHGAGFDALFQHLKTQFSTVLTRKPQASRARSQETYLLARGFIRSAE
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTA_SPOPA
Sequence: MFWVISKQGSTAVAEQEETLVFRVPTEDDGKAIWNLINYPGVLDLLSSYSYFMWAKFFDQTSVVGETNEQIVGFYIGLHTTEYGPDTLFYLASCSDETQRQKGLASRMLQAILHRYAWRNIRYLEATVGTSNEAPEALFQKLSRDLKTAYHVTEFFTEDQFPGKGHEDERLFKIGPFQQV
What is the function of this protein?
Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.
What are the official names of this protein?
L-2,4-diaminobutyric acid acetyltransferase, DABA acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. EctA subfamily.
Protein: PYL1_ARATH
Sequence: MANSESSSSPVNEEENSQRISTLHHQTMPSDLTQDEFTQLSQSIAEFHTYQLGNGRCSSLLAQRIHAPPETVWSVVRRFDRPQIYKHFIKSCNVSEDFEMRVGCTRDVNVISGLPANTSRERLDLLDDDRRVTGFSITGGEHRLRNYKSVTTVHRFEKEEEEERIWTVVLESYVVDVPEGNSEEDTRLFADTVIRLNLQKLASITEAMNRNNNNNNSSQVR
What is the function of this protein?
Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition.  Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA (PubMed:19407143, PubMed:19855379, PubMed:19893533, PubMed:19898420, PubMed:23844015, PubMed:21658606).  Can be activated by both (-)-ABA and (+)-ABA (PubMed:23844015).
What are the official names of this protein?
Abscisic acid receptor PYL1, ABI1-binding protein 6, PYR1-like protein 1, Regulatory components of ABA receptor 9.
What is the protein family that this protein belongs to?
Belongs to the PYR/PYL/RCAR abscisic acid intracellular receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Localizes at the plasma membrane in the presence of a CAR protein (e.g. CAR1 and CAR4).
Protein: PAN3_DROME
Sequence: MCSTYGLLSFEFSDTAAMDPIFFSPTNGIPSESKLATYMNRQNVATPSGYGLNNGFSLLNLDSPLNKKSQVTPQSPEFIPTRLGSTPNFYAPYHNAPMQLSNGLNGVNGLTAAAAAAAAAAAAAAAAVPSSTSSASSASVTISKTANGGASMLALQKTASIASVTIAQQQPQHPQKQQQHPPSVGGGAVSAASAPIAISGAPPNPAAAPFVSSMSAQTPLKGRGAMMRQESPTAAMISGAGPGEKSPPHGMTPHGASPIPSALPTSVHQENVGGTIYFYPTANAQNSQPVVNSMVVDGTHPALHGVSAVAPMSAGVPAAMMYTGHVYPGPSSNVVTMQPKTLLESAFFMPDEMRAEVLARNEISNLIMDAAEAAQHALPLEVENYHALYPLEPPAQPLHAKLTFPATTYRATHNTTGYKYCLRRIHGFRLQSTKCMTLVEMWKKLQHTNVVQLREVFTTKAFGDNSLVLVYDYHPGSQTLLAKYFTPAPETNGYTDPFQGEARPFSHKSNMQRTSNGPLLPEATIWSIIMQLTAGLKAIHHAGLACKVLDPTKIIVTGKRVRFSSCCISDITQFDPNASNPLALVNMHQQDDLTALGRLVLALACRCLQSVQRDNVQSSIDMVTRNYSTDLRNFIVYLFTTNNRRSVTDLMPMIGARFYTQLDALQSKIDMQEDELAKEMENGRLYRILVKLNSINERPDFNLDCTWSETGDRYMLKLFRDYLFHSVTEDGRPWLDHAHIVQCLNKLDAGSIERVQLMSRDEQSVLIVSYAELKNCLENAFSELMSSAAN
What is the function of this protein?
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP).  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex subunit PAN3, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. PAN3 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: NUOD_DECAR
Sequence: MADIRNFTLNFGPQHPAAHGVLRLVLELDGEVVQRADPHIGLLHRATEKLAETRTWVQSVPYMDRLDYVSMMCNEHAYCLATEKLLGIEVPERGKYIRVMFDEVTRILNHLLWIGCHALDVGAMTMALYTFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDRMPQYQESTWTNAKKAAEKNENRSGSVLDFLEDFTNRFPTYHSEYHTLLTDNRIWKQRLVNVGVVTPERALQMGFTGAMLRGSGIAWDLRKKQPYAAYDKINFDVPVGVNGDSYDRYLVRMEEMIQSNNIIKQCIAWLRKNPGPVITDNNKVAPPPRENMKTNMEELIHHFKLFTEGIHVPAGEAYAAVEHPKGEFGIYFVSDGANKPYRMKIRAPGFVHLAGLDEMSRGHMIADVVTIIGSQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL31_TREDE
Sequence: MKKDIHPKYEETTVTCACGNVINTRSTVKDIKVEICSQCHPFFTGKQKLVDTAGRIDRFKKRYNIKD
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PACC1_MOUSE
Sequence: MIRQELSTSYQELSEELEQVVENSEQADERDKELVQVQGPGVVPGVDNESASSSIRFSKACLKNVFSVLLILIYLLLMAVAVFLVYQTITDFREKLKHPVMSVSYKEVDRYDAPGIAFYPGQAQLLSCKHHYEVIPPLASPGQPGDRNCTTQRINYTHPFFNHTMQSALIVQGPQEVKKRELVFLQFRLNQSNEDFSAIDYLLFSSFREFMQSPDKAGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQETSVVNYIDQRPAAERSAQLFFVVFEWKDPFIQKVQDIITANPWNTIALLCGAFLALFKAAEFAKLSVKWMIKIRKRYLKRRGQATNHIS
What is the function of this protein?
Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH (PubMed:31023925).  Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling (PubMed:31023925).
What are the official names of this protein?
Proton-activated chloride channel, PAC, Transmembrane protein 206.
What is the protein family that this protein belongs to?
Belongs to the proton-activated chloride channel family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU6C_AETGR
Sequence: MDLPGPIHDFLLVFLGSGLLFGSIGVVLFTNPIFSAFSLGFVLVCISLLYILSNSHFVAAAQLLIYVGAITVLIIFAVMFMNDSEYSTDLNRWTVGDGITSLICTTILFSLISTILDTSWYGVIWTTRLNQILEQDLISNSQQIGIHLSTDFFLPFELISIILLVALIGAISVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RRF_PSEPF
Sequence: MINEIKKDAKERMTKSVESLAHNFGRIRTGQAHPSILEGVMVPYYGADTPIKQVANITVKDARTLQVVAFERNMLGAVDKAIGSAGLNLNPTNLGELLLISMPALTEETRRGFTKQARDVAEDARVAVRNIRRDANSSLKDLVKEKEISEDEERRAAGEIDDLTKKFVAEIDAKLAEKEKDLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_GUITH
Sequence: MIAMNNKLAQPYAMAFLEFSLDAKQTLDTTIADLTQIKTILHDSVDLSKTLSNPLLSIKAKKEVIKAIFEPNISKNTLKFLLVLCDRGRSANLSSIIDNTIELAYKKASIEIAYVTTATAFSSNQQEALVEKLKSMTSTEQIKLNITVDKTLIGGFKVQIGSKVIDTSIQGQLRQLASHLGSSAI
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, chloroplastic, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RIBA_ECOHS
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: COAX_CAMJE
Sequence: MLLCDIGNSNANFLDDNKYFTLNIDQFLEFKNEQKIFYINVNEHLKEHLKNQKNFINLEPYFLFDTIYQGLGIDRIAACYTIEDGVVVDAGSAITIDIISNSIHLGGFILPGIANYKKIYSHISPRLKSEFNTQVSLDAFPQKTMDALSYGVFKGIYLLIKDAAQNKKLYFTGGDGQFLANYFDHAIYDKLLIFRGMKKIIKENPNLLY
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_ORITI
Sequence: MQFIDEAKIFIKGGNGGDGCVSFRREKFVPNGGPDGGNGGRGGDIIFIGDRHLNTLINFKFKQHFLAQNGRAGAGNNRTGKSGQNLVLKVPVGTQILSNNKEHVIFDLTKDGQEFIIIRGGKGGLGNTYFKSSINQKPRKNTVGEIGDSMWVWLHLKLLSDVGLVGLPNAGKSTFLSAITSAKPKIADYPFTTLTPNLGVVYINNNSFVVADIPGLIAGAHLGQGLGDKFLKHIERCRIIVHLLDITAENLLQNYYTIRDELSSYSLSLKDKTEILCFTKTDTQSNEVIMSKLLELQPVINRVIYPISSYTKYGIKKLLANILSELQKS
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSU1_ARATH
Sequence: MAPDQSYQYPSPSYESIQTFYDTDEDWPGPRCGHTLTAVFVNNSHQLILFGGSTTAVANHNSSLPEISLDGVTNSVHSFDVLTRKWTRLNPIGDVPSPRACHAAALYGTLILIQGGIGPSGPSDGDVYMLDMTNNKWIKFLVGGETPSPRYGHVMDIAAQRWLVIFSGNNGNEILDDTWALDTRGPFSWDRLNPSGNQPSGRMYASGSSREDGIFLLCGGIDHSGVTLGDTYGLKMDSDNVWTPVPAVAPSPRYQHTAVFGGSKLHVIGGILNRARLIDGEAVVAVLDTETGEWVDTNQPETSASGANRQNQYQLMRRCHHAAASFGSHLYVHGGIREDVLLDDLLVAETSQSSSPEPEEDNPDNYMLLDDYLMDEPKPLSSEPEASSFIMRSTSEIAMDRLAEAHNLPTIENAFYDSAIEGYVPLQHGAETVGNRGGLVRTASLDQSTQDLHKKVISTLLRPKTWTPPANRDFFLSYLEVKHLCDEVEKIFMNEPTLLQLKVPIKVFGDIHGQYGDLMRLFHEYGHPSVEGDITHIDYLFLGDYVDRGQHSLEIIMLLFALKIEYPKNIHLIRGNHESLAMNRIYGFLTECEERMGESYGFEAWLKINQVFDYLPLAALLEKKVLCVHGGIGRAVTIEEIENIERPAFPDTGSMVLKDILWSDPTMNDTVLGIVDNARGEGVVSFGPDIVKAFLERNGLEMILRAHECVIDGFERFADGRLITVFSATNYCGTAQNAGAILVIGRDMVIYPKLIHPHPPPISSSEEDYTDKAWMQELNIEMPPTPARGESSE
What is the function of this protein?
Phosphatase that acts as a positive regulator of brassinosteroid (BR) signaling (PubMed:14977918, PubMed:21855796).  Dephosphorylates BES1, a transcription factor that regulates the expression of BR-response genes, thereby playing an important role in the regulation of response to BRs (PubMed:14977918).  Inactivates the negative regulator of BR signaling ASK7/BIN2 by dephosphorylation at 'Tyr-200' (PubMed:21855796).
What are the official names of this protein?
Serine/threonine-protein phosphatase BSU1, Bri1 suppressor protein 1.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. BSU subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RABE2_RAT
Sequence: MAAAPAALALDPQPQEEQKDASESSELSRLRAELAGALAEMETMKAVAEVSESTKAEAVAAVQRQCQEEVASLQAILKDSISSYETQIAALKQERQQQQQDSEEKERELGHLKQLLARAHPLDSLEKQMEKAHEDSEKLREIVLPMEQEIAELKVKLLRAEELIQEIQRRPRQPASLHGSTELLPLSRNPSPPLEPSEEPSGDAGPAAEAFAHNCDDSASISSFSLGGAAGSVSLRGPQGLSPEQEETASLVSTGTLVPEGIYLPPPGYQLVPDSQWEQLQVEGRQLQKELESVRRERDELQEGLSRSNEDCAKQMQVLLAQVQNSEQLLRTLQGTVSQAQERVQRQMAELATSHKCLSQEVKRLNEENRGLRAEQLPSSALQGSEQQEDQDEALPSSIQELHQLVRHTRQQARARQQAQEHEAERLRIEIVKLREALDEETAAKASLEGQLRVQREETDVLEASLCSLRIETERVQQEHHKAQLTDLLSEQRAKALRLQAELETSEQVQRDFVRLSQALQVRLEQIRQADTLEQVRSILDEAPLRDIKDIKDS
What is the function of this protein?
Plays a role in membrane trafficking and in homotypic early endosome fusion.  Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking.  By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis.
What are the official names of this protein?
Rab GTPase-binding effector protein 2, MP13 protein, Rabaptin-5beta.
What is the protein family that this protein belongs to?
Belongs to the rabaptin family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Protein: ARGB_ENT38
Sequence: MNPLIIKLGGVLLDSEEALERLFSALVDYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLSWAKKHHIASVGLYLGDGDSVKVTQLDEELGHVGLAQPGSPKLINTLLEGGFLPVVSSIGVTEEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLISQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGTPIGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTH1_YEAST
Sequence: MSLIHPDTAKYPFKFEPFLRQEYSFSLDPDRPICEFYNSREGPKSCPRGPLCPKKHVLPIFQNKIVCRHWLRGLCKKNDQCEYLHEYNLRKMPECVFFSKNGYCTQSPDCQYLHIDPASKIPKCENYEMGFCPLGSSCPRRHIKKVFCQRYMTGFCPLGKDECDMEHPQFIIPDEGSKLRIKRDDEINTRKMDEEKERRLNAIINGEV
What is the function of this protein?
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.
What are the official names of this protein?
mRNA 3'-end-processing protein YTH1, Yeast 30 kDa homolog 1.
What is the protein family that this protein belongs to?
Belongs to the CPSF4/YTH1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPGP_ECO7I
Sequence: MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLHEANIPVILCSSKTSAEMLYLQKMLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEICQVLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDEHMAQFIARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGRRPTTLGLGDGPNDAPLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWREGLDHFFPAR
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_BACLD
Sequence: MAKRPEDTRVVVGMSGGVDSSVAALLLKEQGYDVIGIFMKNWDDTDENGFCTATEDYEDVIKVCNQIGIPYYAVNFEKQYWEKVFQYFLDEYKAGRTPNPDVMCNKEIKFKAFLEHALSLGADYLATGHYARVDRTDGRVKMLRGLDENKDQTYFLNQLTEEQLSKVLFPIGQLQKSRVREIAKEAGLATAAKKDSTGICFIGERNFKTFLSQYLPAQPGDMRTMEGEFKGRHDGLMYYTIGQRHGLGIGGSGEPWFVVGKDLEKNILYVDQGFDNPLLFSDKITATNVSFVHKGVFGGEEELACTAKFRYRQADHEVTVRMTGTDEAEVVFKEPVRAVTPGQAVVFYKGEECLGGGTIDDVFKDGQQLWYV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPT_ECO45
Sequence: MKRISTTITTTITITTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: THIM_LACPL
Sequence: MELQLLNTLRNHNPIVFNIANFVTVQDVANGLNALGASPIMSAEVQEAETMVQIAGAVCINLGTLTTTQIDQMRVVGKLANQYHKPVVLDPVAVGAVPYRKEVALALLSDFQVDVIRGNAGEIAALAGMDWQAKGIDAGSGQGDLVEIAQACAQQFQCCVILSGPTDVITDGQRVVKVANGTPLFQRHVGSGDLLSSIVAAFTAVSPTDVYQAAQVACLVLAGAGELVASQLTADRPATFAIDLIDRLSLVTVSEIQTIAKVD
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: NA141_ACTEQ
Sequence: MNRLMILVFAAVILALASADDVDIAKRGVPCLCVSDGPRPRGNNLSGTIWMKTGGYGGNGCPKGWHFCGKSRGLLSDCCKQ
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction.  Causes death to crabs.
What are the official names of this protein?
Delta-actitoxin-Aeq2d, Delta-AITX-Aeq2d, Ae4-1, Neurotoxin 4-1.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CST8_RAT
Sequence: MTKPLLLSLIFFIIPAALAVDVDQSKNEVKAQRYFGSISISNANVKQCVWFAMKEYNKGSEDKYLFLLDKTLHATLQITDRMEYHIDVQISRSNCRKPLNNTENCIPQKNPKLEKKLSCSFLVGALPWNGEFDLLSKECKDV
What is the function of this protein?
Performs a specialized role during sperm development and maturation.
What are the official names of this protein?
Cystatin-8, Cystatin-related epididymal spermatogenic protein.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLCL1_HUMAN
Sequence: MVSNFFHVIQVFEKSATLISKTEHIGFVIYSWRKSTTHLGSRRKFAISIYLSEVSLQKYDCPFSGTSFVVFSLFLICAMAGDVVYADIKTVRTSPLELAFPLQRSVSFNFSTVHKSCPAKDWKVHKGKCYWIAETKKSWNKSQNDCAINNSYLMVIQDITAMVRFNI
What is the function of this protein?
May function in mediating immune cell-cell interactions.  May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation.  May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response.
What are the official names of this protein?
Putative C-type lectin-like domain family 1, C-type lectin-like domain family 1 pseudogene, Dendritic cell-associated lectin 1, DC-associated lectin-1, DCAL-1.
Protein: CHI2_CANAL
Sequence: MLSFKSLLAAAVVASSALASASNQVALYWGQNGAGGQERLAQYCQEADVDIILLSFLNLFPDPLNVNFANQCGNTFESGLLHCSQIGADIKTCQSLGKTVLLSLGGGVGDYGFSDVASATKFADTLWNKFGAGEDPERPFDDAVVDGFDFDIEHGGATGYPELATALRGKFAKDTSKNYFLSAAPQCPYPDASLGDLLSKVPLDFAFIQFYNNYCSINGQFNYDTWSKFADSAPNKNIKLFVGVPATSNIAGYVDTSKLSSAIEEIKCDSHFAGVSLWDASGAWLNTDEKGENFVVQVKNVLNQNACVAPSSSATTQSTTTTSSAVTQSTTTTSAAITQSATTTSAAVATKSNQIVTSSSSSSSSIFYGNSTTESSTGIATGTVLPTGSNENAATTGSGSNTKLAISTVTDVQKTVITITSCSEHKCVATPVTTGVVVVTDIDTVYTTYCPLTNSQVYVSVKTVVCTEETCVPSPTSTSQKPKASTTIKGVEKGQTTSYPVVGTTEGVKKIVTTSAQTVGSSTKYVTIELTSTITPVTYPTSVASNGTNTTVPVFTFEGGAAVANSLNSVWFTVPFLLAAFAF
What is the function of this protein?
Chitinase involved in the remodeling of chitin in the fungal cell wall.  Plays a role in cell separation.
What are the official names of this protein?
Chitinase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI- anchor.
Protein: Y0656_EMENI
Sequence: MTNQTIQEALGHGQGNDLGNSDGHRIEYVETIEAYNKWAEVYDTDGNFLQALDTFEMKDLLPRFLCLVQTQTNGKSNMTPGEQVLKLVDLGCGTGRNTLQLAKSAPKEAQIIGLDASPGMLEVAEGNLKAQGVMGTVDERRVVLGVYDLLSPRPESLPVSLRGEARASGAISTLVLEHIPLDKFFEGAARLIRPGGYLLVTNMHAEMGAISQAGFVDVTSGKKIRPTSYAHEVGNVIAAAERAGFEIVPLNGAEKVRERRVNEEMVALLGSRARKWVNVVVWFGLS
What is the function of this protein?
Involved in osmoadaptation.
What are the official names of this protein?
Uncharacterized methyltransferase AN0656.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: GUC2A_HUMAN
Sequence: MNAFLLSALCLLGAWAALAGGVTVQDGNFSFSLESVKKLKDLQEPQEPRVGKLRNFAPIPGEPVVPILCSNPNFPEELKPLCKEPNAQEILQRLEEIAEDPGTCEICAYAACTGC
What is the function of this protein?
Endogenous activator of intestinal guanylate cyclase.  It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
What are the official names of this protein?
Guanylin, Guanylate cyclase activator 2A, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, GCAP-I.
What is the protein family that this protein belongs to?
Belongs to the guanylin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIBBA_MYCBP
Sequence: MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGGAL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: TSN31_PONAB
Sequence: MVCGGFACSKNALCALNVVYMLVSLLLIGVAAWGKGLGLVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNHHQVLLFFYMIILGLVFIFQFVISCSCLAINRSKQADVINASWWVMSNKTRDELERSFDCCGLFNLTTLYQQDYDFCTAICKSQSPTCQMCGEKFLKYSDEALKILGGVGLFFSFTEILGVWLAMRFRNLKDPRANPSAFL
What are the official names of this protein?
Tetraspanin-31, Tspan-31, Sarcoma-amplified sequence homolog.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.