PharMolix/UniProtQA huggingface dataset:
Protein: YCF2_GUIAB
Sequence: MTGHEFKSWILELREILREIKNSHYFLDSWTQFNSVGSFIHIFFHQERFIKLFDSRIWSILLSHNSQGSTSNRYFTIKGVILFGVAVLIYRINNRNMVERKNLYLIGLLPIPMNSIGPRNDTLEESVGSSNINRLIVSLLYLPKGKKIYESSFLNPKESTWVLPITKKCSMPESNWGSRWWRDWIGKKSDSSCKISNETVAGIEILFKEKDLKYLEFVFVYYRDDPIRKDHDWEFFDRLSLRKRQNRINLNSGPLFEILVKHWICYLMSAFREKIPIEVEGFFKQQGAGSTIQSNDIEHVSHLFSRNKWAISLQNCAQFHMWQFRQDLFVSWGKNPPESDFLRNVSRENLIWLDNVWLVNKDRFFRKVRNVSSNIQYDSTRSSFVQVRDSSQLKGSSDQFRDHFDSISNEDSEYHTLLNQREIQQLKERSILWDPSFLQTEGTEIESNRFPKCLSGSSSMSRLFTEREKQMINHMLPEEIEELIGNPTRSVRSFFSDRWSELHLGSNPTERSTRDQKLLKKQQDLSFLRRSENKEMVNLFKIITYLQNTVSIHPISLDSGCDMVPKDEPDMDSSNKISFLNKNPFFDLFHLFHDRNRGGYTLHHDFESEERFQEMADLFTLSITEPDLVYHKRFAFSIDSYGLDPKQFLNGVFNSRYEWKTTSLLVLLVLFPIFYEENESFYRRIRKKRVRISCGNDLEEPKPKIVVFASNNRMEAVNQYRLIRNLIQIQHSTHRYIRNVLNRFFLMNRSDRNFEYGIQRDQIRKDTLNHRTLMKYTINQHLSNLKKSQKRWFDPLIFFSRTERSMNRDPDAYRYKWSTGSNNFQEHLEHFVSEQKSRFQVVFDRLRINPYSIDWSEVIDKKDLSKPLRFFLSKLLLFLSNSLPFLFVSFGNIPIHRSEIYIYELKGPNDPQFLESIGLQIVHLKKLKPFLLDDHETCQKSKFLINGGTISPFLFNKIPKWMIDSFHTRKNRRKSFDNTDSYFSMIFHDQYNWLNPVKSFHRSSLRSSFYKGNQLRFLNNPHHFCFYCNKRFPFYVEKARINNYDFTYGQFLNILFIRNKIFSLCVGKKKHAFWGRDTISAIESQVSNIFIPKAFPQSGDETYNLYKSFHFPSRANPFVRRAIYSIAGISGTPLTEGQIVNFERTYCQPLSDMNLSDSEGKNLYQYLNFNSNMGLIHTPCSEKYLPSEKRKKRSLCLKKCVEKGQMYRTFQRDSAYSTLSKWNLFQTYMPWFLTSTGYRYLKFLFLDTFSDLLPILSSSQKFVSIFHDIMHGSDISWRILQKKFCLPQWNLISEISSKCFHNLLLSEEMIHRNNESPLISTHLTNVREFLYAILFLLLVAAYLVCTHLLFVFGASSELQTEFEKVKSLMIPSSMIELRKILDRYPTSEPNSFWLKNLFLVALKQLGDSLGGNMLLGGGPAYGVKSIRSKKKYLNINLIDIIDLISIIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVNGDWIDDKIESWVANSDSIDDEKREFLVQFSTLTTEKRIDQILLSLTHSDHLSKNDSGYQMIEQPGAIYLRDLVDIHKKYLMNYEFNTSSLAERRIFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSLSRGILVIGSIGTGRSYLVKYLAKNSYLPFITVFLNKFLDNKSQGFDDIDIDDIDASDDIDASDDILDMELELLTSMNALTMNMMPEDEDRLYITLQFELAKAMSPCIIWIPNIHDLDVNESNYFSLGLLVNLLSRDYETRNILVIASTHIPQKADPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFGSITMGSNARDLVALTNEALSISITQKKSIIDTNTIRSALHRQIWDLRSQVRSVQDHGILFYQIGRAVAQNVLLSNCPIDPISIYMKKKSCNEVDYYLYNWYFELGTSMKKLTILLYLLSCSAGSVTQDLWSLPGPDEKNGITPYGLVENDSGLVRGLLEVEGALVGSSRTCSQFDKDRVTLLLRPEPRNPLDMMQKGSCSILDQRFLYEKDESEFEEGEGEGALDRQQIEEDLFNHIVWAPRIWRPWGFLFDCIERPNELGFPYWSRSFRGKRIIYDEEDELQENDSEFLQSGTVQYQTRDRSSKEQGLFRISQFIWDPADPLFFLFKAQPFVSVFSHRELFADEEMSKGLLTPQTNPPTSLYKRWFIKKTQEKHFELLINRQRWLRTNRSLSNGSFRSNTLSESYQYLSNLFLSNGTLLDQMTKALLRKRWLFPDEMQIGFMEQEKDFPFLSRKDMWP
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ARGB_STAAT
Sequence: MKFIVIKIGGSTLSDMHPSIINNIKHLRSNNIYPIIVHGGGPFINEALSNQQIEPHFVNGLRVTDKATMTITKHTLIADVNTALVAQFNQHQCSAIGLCGLDAQLFEITSFDQQYGYVGVPTALNKDALQYLCTKFVPIINSIGFNNHDGEFYNINADTLAYFIASSLKAPIYVLSNIAGVLINDVVIPQLPLVDIHQYIEHGDIYGGMIPKVLDAKNAIENGCPKVIIASGNKPNIIESIYNNDFVGTTILNS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSA_ORYSJ
Sequence: MAHEMMGGFFGHPPPPPATAAVGEEEDEVVEETEEGGHGGGVQGKLCARGHWRPAEDAKLKDLVAQYGPQNWNLIAEKLDGRSGKSCRLRWFNQLDPRINRRAFTEEEEERLMAAHRAYGNKWALIARLFPGRTDNAVKNHWHVLMARRHREQSGAFRRRKPSSSSASPAPAPAPPPPPQPVVALHHHHHRYSQQYSGYSGAAESDESASTCTTDLSLSSGSAAAAAAAAAAANIPCCFYQSTPRASSSSTAACRAPRVAAAADTVAFFPGAGYDFAAAPHAMAPAAASTFAPSARSAFSAPAGRGEPPGAVDQRGGAQATTDSHTIPFFDFLGVGAT
What is the function of this protein?
Transcription factor required for sugar partitioning from leaves to anthers during male reproductive development.  Required for the production of functional pollen grains.  Binds to the promoter of the anther-specific sugar transporter MST8 and regulates its expression.  Regulates the expression of genes involved in sugar partitioning in flower, such as the sugar transporter SUT3, the invertase INV4, the UDP-glucose pyrophosphorylase UGP2 and the starch synthase WAXY.
What are the official names of this protein?
Transcription factor CSA, Myb-related protein CSA, Protein CARBON STARVED ANTHER.
What are the subcellular locations of this protein?
Nucleus.
Protein: DSBL_LELAM
Sequence: MSAKWINSIFKSVVLTAALALPFTASAFTEGTDYMVLEKPIPDADKTLIKVFSYACPFCYKYDKAVTGPVADKVADLVTFVPFHLETKGEYGKQASELFAVTMAKDKAAGVSLFDEKSQFKKAKFAWYAAYHDKKERWSDGKDPAAFLKTGLDAAGMSQAEFEAALKEPAVQQTLQKWKAAYEVAKIQGVPAYVVNGKYLIYTKNIKSIDSMAQLVRELATK
What is the function of this protein?
Involved in disulfide-bond formation.  Acts by transferring its disulfide bond to other proteins.  Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbL.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbL subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: CYSN_FRATW
Sequence: MSHKSDLIATNIQKYLQQRQQKELLRFITCGSVDDGKSTLMGRLLHDSKLIFEDQLASIVADSKKVGTQGDRLDLALLVDGLQSEREQGITIDVAYRYFSTDKRKFIIADTPGHEQYTRNMATGASNCDLAIILIDARKGLQTQTRRHSFICSLLGIKHVIVAVNKMDTVGYSQQIYKSIQDEYLKLAGSLQIPDIRFVPISALDGDNVVSKSPKMPWFRGSPLMHYLETIKIDYAYTDEFRFPVQLVCRPNSEFRGFQGTIVSGSAKIGDTIRVMPSGKITTIKSILSFDGELNEAEAGQSITITTYDEIDISRGDMIVHKDAISHVSSMLRANIVWMSEQPLIEYKDYYIKFLTKQVIGSVNKFNYKTDINTLKEVACGTLELNEIATIELKLSEPVCFDSYQKNRTTGAFIIIDRLTNVTAGAGMVIKPLAANDKKDSTNDYSEFELELNALIRKHFPHWDAKNLRE
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: CYVE_VIOBI
Sequence: AAFALPALASSFEKDVISFRAIQAVLEKRGLSKLEDDPVLSALAHTKTIISNPVIEEALLNGANLKAGNGIPCAESCVWIPCTVTALIGCGCSNKVCYNSLQTKY
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has cytotoxic activity, active against a human lymphoma cell line with an IC(50) of 3. 2 uM.
What are the official names of this protein?
Cyclotide vibi-E, Vbc1.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: DCUP_SYNY3
Sequence: MTEANDLPYLLRVARGEVVKRPPVWMMRQAGRYMKVYRDLRDKYPSFRERSENPDLAIEISLQPWQAFQPDGVIMFSDILTPLPGIGIPFDIIESKGPIIDPPIRTQAQVDQLHALDPESSLPFIKTILGTLRKEVGNQSTVLGFVGAPWTLAAYAIEGKSSKDYKVIKQMAFSEPAILHSFLDKIAEAIAVYVRYQIDCGAQVVQLFDSWAGQLSPQDYDTFALPYQQKVVKLVKEIHPDTPLILYISGSAGILERMGKSGVDIVSVDWTVDMADARQRLGKEMKVQGNMDPGVLFGSQDFIKERILDTVRKAGQGGHIFNLGHGVLVGTPEDNVRFFFETAKQVDQLL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHN_PROMA
Sequence: MPLLLSGRKFRHDLEASGCLAINVPLEGGAETRLLRRLKAAGYKTQITSVRGLGDPEAFLLKLHGIRPPHLGHQNVGRNGALGEVQQVIPQVNELLAGEKSVVLWLLEGQVLSRSEILSLCDLCDKEPRLKIVIEMGGARALRWQSMRSFIQ
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit N, NAD(P)H dehydrogenase I subunit N, NDH-1 subunit N, NDH-N.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhN subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SULA_ECOLX
Sequence: MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: DEOD_ERWT9
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKHIADTFLQDAVEVNNVRGMLGYTGTYKGRKISVMGHGMGIPSCSIYAKELITEFGVKKIIRVGSCGAVRTDVKLRDVVIGMGACTDSKVNRMRFKDHDFAAIADFDMVRNAVDAAQALGVKARVGNIFSADLFYTPDPQMFDVMEKYGVLGVEMEAAGIYGVAAEFGAKALAICTVSDHIRTHEQTTAAERQTTFSEMIEIALESVLLGDKA
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: GLGA_KOSOT
Sequence: MKILFVSYEVYPLAKVGGLADVAGSLPKYLEKEGVSVQIAMPFHKKVKADNIENTGIVITTKHLPEKYSFEIYKTPLPGSGVPVFLFKNDQLIDSDEVYEGTDLALQAIAFSDAVVKFAETLEPDLLHVNDWQPALIPAYISAFYNGKPKTLLTIHNLGYQGEFDKSYFYKTGLPEKLWQEGKAVKNGAFNFLKTGIVTATAISTVSPTYAKEIQTPEYGAGLDETLRALSDRLFGILNGIDYSEYNPATDKRIPVNFDINSLEKKKENKIALQKELGLPVIDVPVIGLISRLVEQKGFDLIEAAAEKILSNDLQFVVLGTGEERYERLFKSLGERFPEKVSANITFNVDLAQKIYAGSDMFLMPSRYEPCGLGQMFAMRYGTIPVVRFTGGLRDTVKEFNPETLEGNGFGFEEYNPDKLLEAVEKAIKIYENKTLWNQLMLNAMNTDCSWDKSAREYIKLYKHVLNSGRDILNA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: THIC_BACC0
Sequence: MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSDTNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWILERGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVDPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAKEFKETGSHLYQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ECT1_ELSFA
Sequence: MALSGLGSGPEGNPNNHQGKAIPTLNPSHGQGPSFLFSWVSFLVPFWSWYPFSPLPLKGIPGENSSSPNGLKNFHGIGLNGTERGMGHFHPISGNRLGLRLTLVAGWFLEPFPTFLAVLIRTQGDSTPSRSFVAFFVGTLGLGQEGITGSFNRKIAGPATIDPQDWAMEEGVLTNFLWPPFTTFFRTTKGFPVQWHGEGSFVVPGIFSLPQPLPWWLLLPDTPTGAGKPPESRQHQPSHSMNGAIVDIPGGLTQTPSSPDRSSSTNSIADEEKKLDYKPTSPTSDTEKGESLPLTASQSEIIASPTFSEMIRVIFSGPTLVLGACYFCTFGAELSINSVLGTFYQRQLGLGLQNAGNLAAIFGLLNIVMRPLGGMASDLLYRKTGSVWSKKALLHTYCVMTGVFCIAIGLARSRSQATLVGLVSGGLAFFLEGANGLTYSHVHPYANGVVSGFTGACGNLGGIVFAIVFRYNSLDYSKVFWIIGAIIIGLQVATCWIKPVPKSVI
What is the function of this protein?
Major facilitator-type transporter; part of the gene cluster that mediates the biosynthesis of elsinochromes, pigments consisting of at least four interconvertible tautomers (A, B, C and D) that have a core phenolic quinone to which various side chains are attached and which play an important role in fungal pathogenesis (PubMed:18957608).  Once elsinochrome is synthesized, it must be exported outside the fungal cells, which is probably accomplished by the ECT1 transporter, to avoid toxicity (PubMed:21199563).
What are the official names of this protein?
Elsinochrome transporter 1, Elsinochromes biosynthesis cluster protein ECT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU2C2_NICSY
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVLIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDSLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRPA_SALNS
Sequence: MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAELRSFVSAMKAASRA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: EST2B_XENLA
Sequence: MASESGAEKGPPTTPAENGQPGVPIAAAVAADEQGMISVDIAGLFYQFSKTFILIFPVYVLGYFGLSFSWLLIALVLLLWWRRNKGNKNSRLYRALAFLETEEKSVKHHIASIDLPAWVHFPDIERAEWLNKTVKHMWPYICQFIEKLFRETIEPAVRGANAHLSTFSFTKIDMGSQPLRINGVKVYTENVDKRQIILDLQISFVGETEIDLEVKRYFCRAGVKSIQLHGTMRVILEPLIGDVPIVGALSIFFLRKPLLEINWTGLTNMLDMPGLNGLSDTIILDIISNYLVLPNRITVPLVSDVQIAQLRFPIPKGVLRIHFLEAQDLMWKDTYMKGLVKGKSDPYGVVRLGNQVFQSKVIKENLNPKWNEVYEALVHEHPGQELEIELFDEDTDKDDFLGSLLIDLVEVEKERVVDEWFTLDEATSGKLHLKLEWLTPKSTTENLDQVLKSIKADKDQANDGLSAALLILYLDSARSLPNNPLEINHDGMKKAAVEKAKKAGKKIGSSPNPYVLFSVGHTVQESKVKYKTAEPVWEQTFTFFVHNPKRQDLEVEVKDENHQNSMGNIKIPLSQILASEDLTLNQRFHLNNSGPNSSLKMKIALRILHVEKPVRSPDEQHTSQVKRPSIFKGKQPPTPQMPAPSPAVAHKPPPTPKLETNKKLENGNKSSTPSASPKRPTELHKSSSSLSGSSFTYSPPHLPTKEPTPSIASDISLPVATQELRERLRQLQNGTTLGQSPLGQIQLTIRHSSQRNKLMVVVHSCRNLIAFSEEGSDPYVRIYLLPDKRRSGRRKTHVHKRTLNPIYDQTFEFSVSLADLQRRTLDVAVKNGGGFLFREKGLLGKLLLEINTEDAAKGWTQWFDLTEDGTRAAASS
What is the function of this protein?
Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.  Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity).  Plays a role in the rapid internalization of fgfr1 that has been activated by fgf1 binding; this occurs most likely via the AP-2 complex.  Required for normal fgf signaling and the activation of downstream signaling cascades via its role in the internalization of activated fgfr1.  Required for normal embryonic development via its role in fgf signaling and the downstream regulation of t/xBRA expression.
What are the official names of this protein?
Extended synaptotagmin-2-B, E-Syt2-B.
What is the protein family that this protein belongs to?
Belongs to the extended synaptotagmin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS). Recruited to the cell membrane via the third C2 domain (By similarity).
Protein: DCUP_ORITI
Sequence: MSKIIQAFNSSNRNYTPIWFMRQAGRYLPEYQMLRKTTNSFFELCYDPIKAAEVTLQPIARFDFDAAIIFSDILVLPDSLGINIRFINNLGPTAEKIPNLLDLQKLKIQNTKISKVYEAIDIVRKKLNKQKSLIGFCGGPWTVLTYILGYNSRNTPKFQEIKSNNKHELILDSINILTKHTIDHLENQILAGADIVQIFDSWAGILPYQEFSEYVIKPTSNIVKTLKEKFPHIKIIGFPKGAGKLYHKYTKETNVDGISCDYNLPLNEMLKLQKNALVQGNLNPNTILSEDSKIIEESVIKIMDTLSNNRFIFNLGHGILPETPIKNVELIVKLVKNYHSSE
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_HAEIG
Sequence: MAKKDYYEVLGLKKGASENDIKRAYKRLASKHHPDKNQGSKEAEEKFKEINEAYEVLGDDQKRAAYDQYGHAAFEQGGGAGGFGGGFGGADFGDMFGDIFGDIFGGGGRGRQRVVRGEDLRYDLEITLEEAVKGTTKDIQINTLAHCDSCGGSGAEKGSKVETCPHCHGSGRIRRQQGFFVSESICPSCHGSGKKIEKPCRSCHGEGRVHKKENLSVKIPAGVDTGNQLRLAGKGAVGENGAPAGDLYVVIHVREHHIFERDGSNLYCEVPISFAIAALGGEIEVPTLDGRVKLKIPAETQTGKLFRMRGKGVASTRSGYAGDLICRIVVETPVNLTSEQKELLHKLEESLQGKDLSKHAPKSSGFLDGVKKFFDNLGKSDK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_METSB
Sequence: MILFPAIDLKGGRCVRLVQGDMAQATVFGDDPAAQAERFERQGFSYLHMVDLDGAFAGKPQNAAAVEAVLARVKIPVQLGGGVRNLATVEAWLEKGVSRIIIGTAALRDPEFTRKAARLHPGKIAVGIDARDGRVAVEGWAETSDITAEELGRRFEDAGVAAIIYTDISRDGLLTGLNIEGTLALAGALKIPVIASGGLASLADVERLLQPDCAKLEGAITGRALYDGRLDPAAALELIARAKTAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_STRPF
Sequence: MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAGWVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAIVWQSRQTAPIAEQLKEDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGELLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEVKSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNTGDEMQLSSNNLLTTIGYGIGGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFALASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDVIDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGLAVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: SPP1_ARATH
Sequence: MERLTSPPRLMIVSDLDETMVDHHKDPENLALLRFNSLWEDAYRHDSLLVFSTGRAQTMYKKLRKEKPLLTPDVIITSVGTEIAYGNSMVPDDNWVEILNKKWDRGIVQEETSKFPELTLQGETEQRPHKLSFNIDKSKVKAVTKELSPRLEKRGVDVKFIFSGGNAFDVLAKGGGKGQALAYLLKKLKTEGKLPINTLACGDSGNDTELFTIPNVYGVMVSNAQEELLEWYAENAKDNANIIHASERCAGGITQAIGHFKLGPNLSPRDVSDFLECKADNVNPGHEVVKFFLFYERWRRGEVENCTTYTSSLKASCHPSGVFVHPSGAEKSLRDTIDELGKYYGDKKGKKFRVWTDQVLATDTTPGTWIVKLDKWEQTGDERKCCTTTVKFTSKEGEGFVWEHVQQIWSEETEIKDDSNWII
What is the function of this protein?
Catalyzes the final step of sucrose synthesis.
What are the official names of this protein?
Probable sucrose-phosphatase 1, AtSPP1.
What is the protein family that this protein belongs to?
Belongs to the sucrose phosphatase family.
Protein: TPPC4_BOVIN
Sequence: MAIFSVYVVNKAGGLIYQLDSYAPRAEAEKTFSYPLDLLLKLHDERVLVAFGQRDGIRVGHAVLAINGVDVNGKYTADGKEVLEYLGNPANYPVSIRFGRPRLTSNEKLMLASMFHSLFAIGSQLSPEQGSSGIEMLETDTFKLHCFQTLTGIKFVVLADPRQAGIDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFGPGS
What is the function of this protein?
Core component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase.  Plays a role in vesicular transport from endoplasmic reticulum to Golgi and autophagy (By similarity).  May play a role in dendrite postsynaptic membrane trafficking (By similarity).
What are the official names of this protein?
Trafficking protein particle complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane. Golgi apparatus membrane. Endoplasmic reticulum. Vesicle. Note=Associated with postsynaptic membranes and in intracellular cisterns and vesicles (Golgi).