PharMolix/UniProtQA huggingface dataset:
Protein: TOLB_COXBU
Sequence: MQKRHPIIYLLITLLIFVPVSYGALDLELTKGVTAAIPIAIMPFAGPSVLAPGDETIPQVIKNDLQNSGQFRVTGSGNLDQTAASLEQIDYSYWRKQKVNALVVGAINPLGMRRYRVAFTLINVFDSNNRLLSESFNVNAKELRNLAHHISDLIYQKLTGVRGVFSTKIAYVLVQASSENTAAKYTLEVADADGFNPQPLLVSDMPIMSPTWSPDGNKIAYVSFEGHRAAIYLQDLATGRRQRLSEAPGINGAPAFSPDGKQLALVLTKTGNPKIYILNLADGHLREITKGWSIDTEPAWSPDGKSLLFTSNRDGTPQIYNYSFADGSINRVTYRGDYNARPSFMPDGKSIIMMHRENGLFGIARQDLSTGQVQILSESGTDESPSLAPNGKMAIYAMEYGGRGVLAQVSIDGQIKLRLPARNGNVQEPAWSPYLGV
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DSBC_PASMU
Sequence: MKKILSTLLMLGMSSLTFANSQQVVEQLQKMGLSGVEVSDSPVKGIKTAVTDNGIFYITEDAKYILDGKLYALSEKGLRDVSSSLLLDKLTAYKNEMVVYPAKDEKHVITVFMDTSCHYCKVLHKQIKEYNDLGITVRYLAFPRGGVQSKTAREMEAIFTAQDPQFALTEAINGNPPKTLKDANITKKHYQLGLQFGVNGTPSIVTEKGELIGGYLKPADLLSELAQ
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by transferring its disulfide bond to other proteins and is reduced in the process.  DsbC is reoxidized by a yet uncharacterized protein.  Also acts as a disulfide isomerase (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbC.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbC subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PCP_CLOBA
Sequence: MKVLITGFDPFGGESINPALEAVKKLPNTISNAEIIKLEIPTVFKKSLEKIEANILAHKPDIVISIGQAGGRFGITPERVAINIDDARIEDNEKNQPIDLKVFEDGENAYFTTLPIKAMVKEMQESGIPSSVSNSAGTFVCNHVMYGVLYMINKKYPNIKGGFIHVPYIPSQVVSKPNMPSMSIEDISKGLELSVKAAVENNTDIKTAQGEIC
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1696_HAEIN
Sequence: MLSIIVPSYNRKAEVPALLESLTQQTSSNFEVIIVDDCSKERVVVEQSYSFPVTVIRNETNQGAAESRNVGARTSKGDWLLFLDDDDCFMPEKCEKVLQVIEQNPNINFIYHPAKCEMVNEGFTYVTQPIEPQEISTERILLANKIGGMPMIAIKKEMFLKIGGLSTALRSLEDYDFLLKLLQEPSFTPYKINEPLTYCTFHTKRSSVSTDTTNTQKAIDYIREHYVKTVEQARNFDINASYILAYPHIMNLSRKAAKYYFDIFKKTKSIKQFIITLVILISPKLAINLKRLGK
What are the official names of this protein?
Uncharacterized glycosyltransferase HI_1696.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: UPPP_STAAW
Sequence: MFIIELIKGIILGVVEGLTEFAPVSSTGHMILVDDMWLKSSEFLGSQSAFTFKIVIQLGSVFAAAWVFRERFLEILHIGKHKHVEGDNNQQRRSKPRRLNLLHVLVGMVPAGILGLLFDDFIEEHLFSVPTVMIGLFVGAIYMIIADKYSAKVKNPQTVDQINYFQAFVIGISQAVAMWPGFSRSGSTISTGVLMKLNHKAASDFTFIMAVPIMLAASGLSLLKHYQDIQITDIPFYILGFLAAFTVGLIAIKTFLHLINKIKLIPFAIYRIVLVIFIAILYFGFGIGKGI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOM_BUCAI
Sequence: MLLSLLIIIPFLSSFFSFFSPRLHNNFPRWIALSGIIATLLVVIQIFFQENYHIFQIRHYPNWNCQLIVPWISRFGIEFNIALDGLSIIMLIFSSFLSIIAIICSWNEIKKNEGFFYFNFMLVFTGIIGVFISCDLFLFFCFWEIMLIPMYFLIALWSDKTEKKKNFLAANKFFLYSQTSGLILLSSILLLVFSHYYSTNILTFNYNLLINKPINIYVEYIVMIGFFLSFAIKMPIVPFHGWLPDIHSRSLSCGSVEIIGVLLKTAPYALLRYNLVLFPDSTKSFSLIAVFWGIISIFYGAWIAFSQTNIKRLIAYSSVSHMGLILIGIYSNNERALQGVVIQMLSNSLTVAALCILSGQIYKRFKTQDMSKMGGLWSCIYWIPGFSLFFSLANLGVPGTGNFIGEFLILSGVFEVFPLVSILATIGIVFSSIYSLNVIQKIFYGPCKQNIKVFFINKQEVWTIIALVFTLVFLGLNPQKIIDVSYNSIHNIQKEFNNSILKIRS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit M, NADH dehydrogenase I subunit M, NDH-1 subunit M.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYP23_ARATH
Sequence: MGITRNLILGLACLAFVSIAKALPHEPELGSARVVFQTSYGDIEFGFYPTVAPKTVDHIFKLVRLGGYNTNHFFRVDKGFVAQVADVASGRSAPMNEEQRKEAEKKIVGEFSDVKHVRGTLSMGRYDDPNSAQSSFSMLLGNAPHLDRQYAVFGKVTKGDETLSKLEEVPTRREGIFVMPTERITILSTYYYDTKMESCEEERSVLKRRLQASFVEVERQRMKCFP
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase CYP23, PPIase CYP23, Cyclophilin of 23 kDa, Cyclophilin-23.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: S11IP_HUMAN
Sequence: MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKLVHVAGPGPTGPIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDSSLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNLLEGHRELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLSDSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAGWFVQQHPELELMSSFRERFGRNWLQYRSHLEPSGNPLPATPTTSAPSAPPASSQGPDTAPRPSPPQEEARGPQESPQKMSEEVRAEPQEEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEAELCRPLLVCPLEGPEGVRGRECFLRVTSAHLFEVELQAARTLERLELQSLEAAEIEPEAQAQRSPRPTGSDLLPGAPILSLRFSYICPDRQLRRYLVLEPDAHAAVQELLAVLTPVTNVAREQLGEARDLLLGRFQCLRCGHEFKPEEPRMGLDSEEGWRPLFQKTESPAVCPNCGSDHVVLLAVSRGTPNRERKQGEQSLAPSPSASPVCHPPGHGDHLDRAKNSPPQAPSTRDHGSWSLSPPPERCGLRSVDHRLRLFLDVEVFSDAQEEFQCCLKVPVALAGHTGEFMCLVVVSDRRLYLLKVTGEMREPPASWLQLTLAVPLQDLSGIELGLAGQSLRLEWAAGAGRCVLLPRDARHCRAFLEELLDVLQSLPPAWRNCVSATEEEVTPQHRLWPLLEKDSSLEARQFFYLRAFLVEGPSTCLVSLLLTPSTLFLLDEDAAGSPAEPSPPAASGEASEKVPPSGPGPAVRVREQQPLSSLSSVLLYRSAPEDLRLLFYDEVSRLESFWALRVVCQEQLTALLAWIREPWEELFSIGLRTVIQEALALDR
What is the function of this protein?
May regulate STK11/LKB1 function by controlling its subcellular localization.
What are the official names of this protein?
Serine/threonine-protein kinase 11-interacting protein, LKB1-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the STK11IP family.
Protein: DNM1L_DANRE
Sequence: MEALIPVINKLQDVFNTVGADIIQLPQIAVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVDPEDRRKTSEENGVDGEEWGKFLHTKNKIYTDFDEIRQEIENETERVSGNNKGISDEPIHLKIFSPHVVNLTLVDLPGITKVPVGDQPKDIELQIRELILKYISNPNSIILAVTAANTDMATSEALKVAREVDPDGRRTLAVVTKLDLMDAGTDAMDVLMGRVIPVKLGLIGVVNRSQLDINNKKSVADSIRDEHGFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLSAQYQSLLSSYGEPVEDMSATLLQLITKFATEYCNTIEGTAKYIETAELCGGARICYIFHETFGRTLESVDPLGGLTTIDVLTAIRNATGPRPALFVPEVSFELLVKRQVKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTSLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRMRELPTSVPRDKMAGGAQAEQEGGTGTWRGMLKKGDEGQGEEKTKLQSSIPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDSLQSELVGQLYKPALLDDLLTESEDMAQRRNEAADMLKALQKASQVIAEIRETHLW
What is the function of this protein?
Functions in mitochondrial and peroxisomal division.  Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism.  The specific recruitment at scission sites is mediated by membrane receptors like MFF, MIEF1 and MIEF2 for mitochondrial membranes.  While the recruitment by the membrane receptors is GTP-dependent, the following hydrolysis of GTP induces the dissociation from the receptors and allows DNM1L filaments to curl into closed rings that are probably sufficient to sever a double membrane (By similarity).  May play a role in the circadian control of mitochondrial ATP production (By similarity).
What are the official names of this protein?
Dynamin-1-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus. Endomembrane system; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein. Peroxisome. Membrane, clathrin-coated pit. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane.
Protein: RL3_THEVO
Sequence: MATPHHSRRGSMAYYPRVRAKSIEPRIRSWPEISGPVKVQGFAGFKVGMTHVEMVDYRKTSVTAGQPIFVPVTVIEVPPLDVIGIRLYDEDEEGNMVVVYEKWTQNLDKELFKKITTFKEVKEKPVPETYADVRLIVATRNKDVPGIPSKKPEIFELRIGGGNSVKERFEYATAHLGKTIRFEDFSKPGKFVDVLSVTKGKGFTGHVQRFGVKLLPRKNRKHRRMIGTLGPWHPDWVRNTVPQAGQMGYQQRTISNVRVLKYSKGEDADTINVRGGFLHYGLVKNDYVLLFGSVPGPAKRLIKMRDPARQKVPDIDNVKLDYISLESKQGD
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RS6_LACLS
Sequence: MTKYEILYIIRPNIDEEAKTALVERFDAILTENGAANLESKDWEKRKLAYEINDFREGIYHIATFEAETTSEALSEFDRLAKINLDILRHMIVKVEA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y3602_ACIAD
Sequence: MFRWAIIFAVIALIASLLGFGGVAGLSKDFAVILLVVAVILAIVGFISRGRV
What are the official names of this protein?
UPF0391 membrane protein ACIAD3602.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRBA1_RAT
Sequence: METQTVQRELETLPTTKMAQTNPMPGSMGPWKITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVECGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKITIFEKENFIGRQWEICDDYPSLQAMGWFNNEVGSMKIQCGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGTHAQTSQIQSIRRIQQ
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin A3.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: GPDM_BOVIN
Sequence: MAFQKAVKGTILVGGGALATVLGLSHFAHYKRKQVNLAFVEAADCISEPVNREPPSREAQILTLKNTSEFDVLVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAIMKLDIEQYRMVKEALHERANLLEIAPHLSAPLPIMLPIYKWWQLPYYWVGIKLYDLVAGSNCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEVMSLLKKTDPQTGKERVSGARCKDVLTGEEFDVRAKCVINATGPFTDTVRKMDDKDTTAICQPSAGVHIVMPGYYSPESMGLLDPATSDGRVIFFLPWQKMTIAGTTDTPTDVTHHPIPSEEDINFILNEVRNYLSCDVEVRRGDVLAAWSGIRPLVTDPKSADTKSISRNHVVDISESGLITIAGGKWTTYRSMAEDTINAAVKAHNLKAGPSRTVGLFLQGGKDWSPTLYIRLVQDYGLESEVAQHLAATYGDKAFEVAKMASVTGKRWPIVGVRLVSEFPYIEAEVKYGIKEYACTAVDMISRRTRLAFLNVQAAEEALPRIVELMGRELNWDDSKKEEELETARKFLYYEMGYKSRSEQLTDRSEISLLPSDIDRYKKRFHKFDADQKGFITIVDVQRVLESIGVQMDENTLHEILNEVDLNKNGQVELNEFLQLMSAIQKGRVSGSRLAILMKTAEENLDRRVPIPVDRSCGGL
What is the function of this protein?
Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase, mitochondrial, GPD-M, GPDH-M.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL4_METST
Sequence: MAKINVYSLKGDITEEIELPEIFEEEYRPDVIKRAVISMQTARIQPWGTDPMAGKRTTAESFGSGRGAAMVPRVKGSSKAAFVPQAIGGRKAHPPRVNTIYHEKINKKERTLAIRSAIAATANKELVEQRGHQVSELEQIPFVIDDEIETVKTTKETREIFKDLGIMDDIVRAKKGRKIKSGKGKLRGRKYRTPKGPLVVVGNDRGISLGARNHAGVDVVEVNNINAELLAPGTHAGRLTIYTKSAIEKLGDLFQKNRS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: NAC82_ARATH
Sequence: MGKTQLAPGFRFHPTDVELVRYYLKRKILGKKLLVDAIAEVDIYKFEPPDLPDMSFIRSGDLKWHFFCPREKKYASGVRANRATECGYWKTTGKERPVLCNSEVVGKIKTLVYHFGKSPRGERTDWVMHEYRLDDKVLTQMNVPQDTYVVCVLFKKDGPGPRNGAQYGAPFKEEDWSDEEVRTDVPSTSNPTNLLEPSKETTLALTAPDDSNKDCFGGMISESCVSDFLPATTNTTSELPHPSDAATTPMSTAPLAETVQTPNNDDLYSMLDLFDDDEEFLGFNNNEVRYDPGVSAPVCLEEEGIFNGLPELSSMPRTASYDLVENSELYLELQDLTAPLNPQTGLQDLTAPFNPQTGLQDLTAPFNHQTGLQDHTAPFNPQTGLQDHTAPFNHQTGLQDLTAPFNPQTGLQDLTAPFNPQTGLHDLTSPFNPQTGLQDLTAPLNPQTGNRNDPRSSSFLYNQGHFDFSGGNDDDPYGFSASMRHRPKM
What is the function of this protein?
Transcriptional regulator that binds specific DNA sequences on the promoter regions of target genes.
What are the official names of this protein?
NAC domain-containing protein 82, ANAC082, Protein VND-INTERACTING 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOC2_PEA
Sequence: RLVEVVQHIVVRRTDCGTIRGISVNTRNGMMPEIILIQTLIGRVVAENIYIGSRCIVVRNQDIGIGLINRFITFQTQPIFIRTPFTCRNTSWICRLCYGRSPIHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEYVRAPSNGKIKLNEDLVHPTRTRHGYPAFICNIDLYVTIESDDIIHNVIIPPKSFLLVQNDQYVKSEQVIAEIRAGTYTFNLKERVRKHIYSDSEGEMHWSTDVYHASEFMYSNVHILPKTSHLWILSGKSCRSNTIHFLLRKDQDQITMDSLSNGKTNISNLLERNDQVKHKLFRFNTFGTKEKGISDYSIFNEIICTDHSYPAIFHDTFYFLAKRRRNRFLIPFPFQSIQERKNERMSPSGVSIEIPINGIFHRNSIFAYFDDPQYRRHSSGITKYRTIGIHSIFQKEDFIEYRGIKELKPKSQIQVDRFFFIPEEVHILPKSSSLMVRNNSLVGIGTPITFNIRSRVGGLVRLDKKKKKIELKIFSGNIHFPGEMDKISRHSAILIPPGTVKKKKCNKSKKIKNWIYVQWIATTKKKYFVLVRPVILYEIPDSNNFVKLFPQDLFQEKDNLELKVVNYILYGNGKSIRGISDTRIQLVRTCLVFNWDDGKNSSSIEEAPASFIEVRTNGLIEYFLRIDLVKSNTSYIRKRNEPSGFGLIGDNKSDRINPFFSIHSKGKIQQSLSQNHGTIRMLLNRNKECRSWIILSSSNCFQMRPFNNEKSHNGIKKDPIISINNNGPLGIALQVANFYSLYHLITHNQISIIKNLQLDKLTEIFQVIKYYLMDENDKICKPDLYSNIILNPFHLNWFFLHHFYCEKTFTRISLGQFICENICIAQMKNRPHLKLKSGQVIIVQMDSVIIRSANPYLATPGATIHGHYGEILSQGDILVTFIYEKSRSGDITQGLPKVEQILEIRSIDSISMNLEKRIDAWNECITKIIGIPWGFLIGAELTIAQSRISLVNKIQKVYRSQGVHIHNRHIEIIVRQITSKVLVSEDGMSNIFLPGELIGLLRAERTGRALEEAICYRALLLGVTKTSLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGMIPVGTGFKRIMHRSRSRQHNKITRKKKLFEVEIRNLLFHHRKLLDFANFKEFM
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AROC_SHIDS
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: FEN1A_DANRE
Sequence: MGIHGLAKLIADHAPSAIKEHEIKSYFGRKIAIDASMCIYQFLIAVRQDGNVLQNEDGETTSHLMGMFYRTIRMLESGIKPVYVFDGKPPQLKSGELEKRVERRAEAEKLLAQAQEAGEQENIDKFSKRLVKVTKQHNEECKKLLSLMGVPYIEAPCEAEASCAALVKAGKVYATATEDMDGLTFGTTVLLRHLTASEAKKLPIQEFHFSRILQDMELTHQQFIDLCILLGCDYCGTIKGIGPKRAIDLIKQHGSIEEILENIDPNKHPAPEDWLYKEARGLFLEPEVVDGTSVDLKWNEPDEDGLIQFMCAEKQFSEDRIRNGCKKITKSRQGSTQGRLDTFFTVTGSISSKRKEPETKGSAKKKQKTSATPGKFKKGK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: RL11_ANADE
Sequence: MKKVTGQIKLQLPAGKANPAPPVGPALGQHGVNIMEFCKQFNAATQAQAKEALIIPVIITVYQDRSFTFVLKTPPAAILLKKAAGLHTEKKKGSGAHKPGKEKVGQVTRKQVEQIAKTKMQDMTAGTLEAAMRTVEGTALSMGIEIVG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: B2MG_MUSCR
Sequence: SPQIQVYTRHPPENGKPNILNCYVSQFHPPHIEIEMLKNGKKIPEIEMSDLSFSKDWSFYILAHTEFTPTDSDTYSCRVTHVSMKEPKTVNW
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TLCOD_ALOMR
Sequence: MKLSIFFVLFFIAIAYCQPEFLDDEEDEVEETLPVAEEGREKSCITWRNSCMHNDKGCCFPWSCVCWSQTVPRNSSRKEKKCQCRLW
What is the function of this protein?
Modulates P-type voltage-gated calcium channels (Cav2. 1/CACNA1A) in rat cerebellar Purkinje cells and hippocampal CA1-CA3 neurons.  At saturating concentrations (>10 nM) the toxin decelerates activation kinetics and slightly increases peak amplitude without affecting deactivation kinetics (By similarity).
What are the official names of this protein?
Omega-lycotoxin-Gsp2671d, Omega-LCTX-Gsp2671d, Omega-Lsp-IA-like 3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin (omega-lctx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROE_CLOBM
Sequence: MYTTGLIGKNINYSESPEIHNNYYKKNNIPFFYKIFNLNQDQIDYFIKNLHKNNIKGFNVTIPYKETILQYLNDIVYPADKIGAVNTVVVQEDKLIGYNTDYIGFIKSLQYYNIQVKNFKCLIIGSGGSAKCIYYALKELNAGDICIVSRNPEKARLKFEKKVKILNIKDENKLDRYDLIVNCTPIGGPNFREQKPVKLKEVKKNCVVYDLNYTPKRSKLLKEAKENGAFIINGEKMLIFQAYSAIGLWCLNGIKGGR
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: FTSQ_RICPR
Sequence: MRQKTISNKNKQTKNTNNISLRRKLGLMYKKAILVLKIVLMIFVCLFVFTKYFTSIKTYLITNIYQVTTKLGFRLENVIIEGQQNVDELTILKVLNANKSSPIFSLKLDEISNNLKKSKWIKEVYVSRRLPNTVYIKLFEREPIAIWQINNQLFLIDEEGYKISKDIQPFSHLLHVVGEGANIYASKLVLELQKYPALLNKTLVAIRVGDRRWDLNLKGNISIKLPEKEFETALKYIDALNKTNKLFNQNYKALDLRDRNKYYIQKY
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: FTSH1_CONWI
Sequence: MSRFFKSAAFPILIVVVLAFFAQRLINPGDSGPRYDYSTFQQDLSEGNVKSAVVKTKGNLLEVTLKSPANQKHEVGYVPDNGNTLVGQLERERVAFDIEGTKSNGWLSLLTYVLPFLIFIGFWIFLMNQVQGGGSKVMSFGKSRARRLSVDSPKITFRDVAGADEAVEELHEIKEFLENPKKFQALGARIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKQNAPCIIFMDEIDAVGRHRGAGMGGGHDEREQTLNQLLVEMDGFEAKDNIIMIAATNRPDILDPALLRPGRFDRQVTVDRPDRKGRSKILEVHTRGKPLAREIDIDALAGQTPGFTGADLANLVNEAALLAARTGKREITQVELEEGIMRVIAGPEKKTRVMSSEERRITAYHEMGHALVGHFLEHADPVHKISVIGRGQALGYTISMPQEDKFLTTRAALGDTMAMTLGGRAAEEIIFGEITTGASNDLEKVTGTAKQMVMRFGMSEKLGPRVFGHDQSQPFLGREFSSQADYSDEIAREIDDEIRRIVETAHQSAKDILTEHRESLVYISEILIKRETIEKDQFEALVDGRTEEEVFGAEASPPPDVPLPPATERGRDTPRPLPRPGLAGGAAEMHFPERPELA
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: RS19_RHOOB
Sequence: MPRSLKKGPFVDDHLLAKVDVQNEKGTKQVIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVSDSMVGHKLGEFAPTRTFKGHIKDDRKAKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ACCD_GEOSW
Sequence: MWKDLFTKKKKYASIPSEKVRSEVPEGIMTKCPKCKKIMYTKELVKNLRVCMSCGYHHTMPSRERINSLLDEGSFHEYDADMVSVNPLQFPGYIEKLEEDRRKSNLNEAVITGEGTLNGYPIVIAVMDSAFRMGSMGSVVGEKITRAIEKARELHVPFLIFTASGGARMQEGVLSLMQMAKTSAALKLFSDEGGLIISVMTHPTTGGVSASFASLGDYNFAEPGALIGFAGRRVIQQTVREELPEDFQTAEFLLKHGQLDAVIHRHDLKDTLTTVLDIHQGGGGHGWWQS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.