PharMolix/UniProtQA huggingface dataset:
Protein: WFS1_MOUSE
Sequence: MNSGTPPPSPSGPPPPPAPQPQARARLNATASLEQDKIEPPRAPRPQADPSAGRSAGEAAAPEPRAPQTGSREETDRAGPMKADVEIPFEEVLEKAKAGDPKAQTEVGKHYLRLANDADEELNSCSAVAWLILAAKQGRREAVKLLRRCLADRKGITSENEAEVKQLSSETDLERAVRKAALVMYWKLNPKKKKQVAVSELLENVGQVNEQDGGAQPGPVPKSLQKQRRMLERLVSSESKNYIALDDFVELTKKYAKGIIPTNLFLQDEDEDEDELAGKSPEDLPLRQKVVKYPLHAIMEIKEYLIDVASKAGMHWLSTIVPTHHINALIFFFIISNLTIDFFAFFIPLVVFYLSFVSMVICTLKVFQDSKAWENFRTLTDLLLRFEPNLDVEQAEVNFGWNHLEPYIHFLLSVVFVIFSFPLASKDCIPCSELAVISTFFTVTSYMSLSSSAEPYTRRALVTEVAAGLLSLLPTVPVDWRFLKVLGQTFFTVPVGHFIILNVSLPCLLYVYLFYLFFRMAQLRNFKGTYCYLVPYLVCFMWCELSVVILLQSTGLGLVRASIGYFLFLFALPILVAGLALMGTVQFARWFLSLDLTKIMVTTVICGVPLLFRWWTKANFSVMGMVKSLTKSSMVKLILVWLTAILLFCWFYVYRSEGMKVYNSTLTWQQYGFLCGPRAWKETNMARTQILCSHLEGHRVTWTGRFKYVRVTEIDNSAESAINMLPFFLGDWMRCLYGEAYPSCSSGNTSTAEEELCRLKQLAKHPCHIKKFDRYKFEITVGMPFGTNGNRGHEEDDITKDIVLRASSEFKDVLLNLRQGSLIEFSTILEGRLGSKWPVFELKAISCLNCMTQLSPARRHVKIEQDWRSTVHGALKFAFDFFFFPFLSAA
What is the function of this protein?
Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store (By similarity).  Negatively regulates the ER stress response and positively regulates the stability of V-ATPase subunits ATP6V1A and ATP1B1 by preventing their degradation through an unknown proteasome-independent mechanism (By similarity).
What are the official names of this protein?
Wolframin.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle. Note=Co-localizes with ATP6V1A in the secretory granules in neuroblastoma cell lines.
Protein: ASSY_SPHAL
Sequence: MSDSIKRVVLAYSGGLDTSVILKWLQVTYGCEVVTFTADLGQGEELEPARAKAELMGIKPEHIYIDDLREEFVRDFVFPMMRANARYEGDYLLGTSIARPLISKRLVEIARETGADAVAHGATGKGNDQVRFELSAYALNPDIKVIAPWREWDLTSRTALIAWAEQHQIPVPKDKRGESPFSTDANLLHTSSEGKVLEDPWEETPDYVYSRTVNPEDAPDTPEYITIDFERGDGVALNGQAMSPATLLAALNDLGRKHGIGRLDLVENRFVGMKSRGMYETPGGEIYARAHRGIESITLDRGAAHLKDELMPKYAELIYNGFWFAPEREMLQAAIDHSQANVTGTVRLKLYKGNASVVGRKSPFSLYSERHVTFEDDAGAYDQKDAAGFIRLNALRLKLLARQGR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP3_RAT
Sequence: MAGARGLLCLWLGCFCLNLAQGQRPNLHLPGLRGTESSDRMTGGGPSPDLRPHDKVSEHMLWLYDRYSGSNRAQATRTPGSQLPGPQPLRGGNTVRSFRAAAAGTLQRKGLHTFNLTSLTKSENILSATLYFYIGELVNTSVNCPESQGCSHDSQRQHIQIDLSAWTLQSNQSQLLGHLSVDTAKPYRDSMSWLSKDITQLLRKAKQDEEFLIGFNITSRAHELPKRMLLFPEPYILVYANDAAICEPESVVSSLQRHRDFTAGTVPRLDSHVREALSVERRKKRSTGILLPLQNNELPGAEYQYKEAGVWEERKPYKSLQTQPPEKSRSKKKQRKGPHQKGQTLQFDEQTLKKARRKQWIEPRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVVSGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVDSCACR
What is the function of this protein?
Negatively regulates bone density.  Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification (By similarity).
What are the official names of this protein?
Bone morphogenetic protein 3, BMP-3.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: DOIS_MICEC
Sequence: MEVEIRLGSVRYPFRLGTDCLGAIVEDLVAMSASRLLIVCDSNTGPLFGAELVERLSPRVPANLLIHRAGEPYKDLQAVGTLADSALQLGADRASVVVAVGGGVIGNIAGLMAALLFRGIRLVHIPTSLIAMSDSVLSLKQAVNACVGKNLMGTFYAPESVLADTAMLRSLPFRETVSGLCEVVKNSLAIRPSMVEMLRTSLRQDAVYDDETMYEIISESILAKASVTVDDMHECRAGLVLEYGHTVGHAIEYTAAGGLSHGQAIGLGMVVAAEVSHRLGHLDQEAVALHRELLTRAGAMVTIPEEVDLDEVMHRLRFDNKRGYLADPAESSAMVLLGGLGEPLWHDGRPLVSVPMALVGEVVNEIARPEIPNFELVAPVETVEEGRVPDTVGAADG
What is the function of this protein?
Catalyzes the intramolecular carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose (DOI).
What are the official names of this protein?
2-deoxy-scyllo-inosose synthase, DOI synthase, DOIS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. DOI synthase family.
Protein: PPLA_CHICK
Sequence: MEKVQYITRSALRRASTLEVNPQARQRLQELFVNFCLILICLLLICIIVMLL
What is the function of this protein?
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+).  Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2.  Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle.  The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.  ATP2A2 inhibition is alleviated by PLN phosphorylation (By similarity).
What are the official names of this protein?
Cardiac phospholamban, PLB.
What is the protein family that this protein belongs to?
Belongs to the phospholamban family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Sarcoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Membrane; Single-pass membrane protein.
Protein: MFTE_MYCTU
Sequence: MNSSYHRRVPVVGELGSATSSQLPSTSPSIVIPLGSTEQHGPHLPLDTDTRIATAVARTVTARLHAEDLPIAQEEWLMAPAIAYGASGEHQRFAGTISIGTEALTMLLVEYGRSAACWARRLVFVNGHGGNVGALTRAVGLLRAEGRDAGWCPCTCPGGDPHAGHTETSVLLHLSPADVRTERWRAGNRAPLPVLLPSMRRGGVAAVSETGVLGDPTTATAAEGRRIFAAMVDDCVRRVARWMPQPDGMLT
What is the function of this protein?
Peptidase involved in the biosynthesis of the enzyme cofactor mycofactocin (MFT).  Catalyzes cleavage of the MftC-modified MftA peptide to liberate its final two residues, which consist of a cross-linked valine-decarboxylated tyrosine dipeptide (named 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one or ADHP).
What are the official names of this protein?
Mycofactocin precursor peptide peptidase.
What is the protein family that this protein belongs to?
Belongs to the creatininase superfamily.
Protein: Y449_BACCN
Sequence: MGFPKEGEKVQIHSYKHNGSIHRMWEETTILKGTQSLVIGANDRTLVTESDGRTWITREPAICYFHANYWFNVIGMLREDGVYYYCNLSSPFAYDLEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHSKMMKYPPVIDTILKRNVEYLRKWIHQRKGPFAPDFVDMWYERYLMYRD
What are the official names of this protein?
UPF0374 protein Bcer98_0449.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: INS_CALMI
Sequence: VPTQRLCGSHLVDALYFVCGERGFFYSPKQIRDVGPLSAFRDLEPPLDTEMEDRFPYRQQLAGSKMKRGIVEQCCHNTCSLVNLEGYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTS_COXBR
Sequence: MELQTKSPTTQNDFSQHTPMMRQYLRIKAEYPDLLVFYRMGDFYELFYDDAKKAAKLLNITLTARGQSAGHAIPMAGVPYHAVENYLTKLVRLGESVVICEQIGDPATSKGPVAREVTRIITPGTVSDEALLDEHRDNTLMVIHQEKDRFGIATLDITSGRFLIQEIISENALFAEIERIRPAELLISEENSVHPLKADSIKRRPPWEFDHATALTLLCQQFQTKSLDGFGITHLPLAITAAGCLLQYVNYTQKSALPHIHSIQAEQNEEALFIDANTRRNLELITNLQGEEVHSLAWLLDHTATPMGSRLLRRWINRPLRDQILLQQRQNAVSTLLEKRNYSEIYENLRHIGDLERIVARIALRSARPRDLMQLRQALGVLPTLHQQLTNLPLNKQLQEIKNNLGLFDELFRLLQKAIIENPPIVIRDGGVIADGYDAPLDELRNMSTNSHQFLIDLEQQERERTKINTVKVGYNRIHGYYIEISRAQAKQAPTEYIRRQTLKNVERYITPELKIFEDKVLSSRSRALAREKELYEQLLDTLIEKLIPLQQCASAIANLDVLNTLAERADTLNFNAPQFCDYPIIKIEAGRHPIVENVMTDPFMPNDTHLDEKRRMLIITGPNMGGKSTYMRQTALITLLAYIGSFVPAKNAQLGPIDRIFTRIGAADDLASGRSTFMVEMTETAAILHNATEESLVLMDEVGRGTSTFDGLSLAYACASYLATKLKAFALFATHYFELTALASTLQAVKNVHLDAVEHEEKIIFLHALREGPANKSYGLQVAQLAGIPRSVIQHARQKLEELENPVISETQQPQQNELFLPIENPVLTQLDKLNPDNLTPKQALDILYQLIQLRQQK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PIR7B_ORYSI
Sequence: MEISSSSKKHFILVHGLCHGAWCWYRVVAALRAAGHRATALDMAASGAHPARVDEVGTFEEYSRPLLDAVAAAAAPGERLVLVGHSHGGLSVALAMERFPDKVAAAVFVAAAMPCVGKHMGVPTEEFMRRTAPEGLLMDCEMVAINNSQGSGVAINLGPTFLAQKYYQQSPAEDLALAKMLVRPGNQFMDDPVMKDESLLTNGNYGSVKKVYVIAKADSSSTEEMQRWMVAMSPGTDVEEIAGADHAVMNSKPRELCDILIKIANKYE
What are the official names of this protein?
Esterase PIR7B.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: SOMA_NEOVI
Sequence: MAAGPRNSMLLVFALLSLPWPQEVGAFPAMPLSSLFANAVLRAQHLHQLAADTYKDFERAYIPEGQRYSIQNAQAAFCFSETIPAPTGKDEAQQRSDMELLRFSLLLIQSWLGPVQFLSRVFTNSLVFGTSDRVYEKLKDLEEGIQALMRELEDGSPRAGPILKQTYDKFDTNLRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCAF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENTP8_MOUSE
Sequence: MGLSWKERVFMALLGVAAASGLTMLVLILVKAINVLLPADTKFGIVFDAGSSHTSLFVYQWPANKEKDTGVVSQALTCQIEGPGISSYTSDPTQAGESLKSCLEEALALIPQAQHPETPTFLGSTAGMRLLSQKNSSQARDILAAVSQTLSKSPVDFWGAKILAGQDEGAFGWITINYVLGMLLKYSSGQWILPEEGMLVGALDLGGASTQISFVPQGPILDQSTQVTFRLYGANYSVYTHSYLCFGRDQILNRLLAKLAQDRLSSQVAPVRHPCYHSGYQAILPLSSLYDSPCIHTTDSLNHTQNLTVEGTGDPGNCVVALRSLFNFSSCKGQKDCAFNGIYQPPVHGQFYAFSNFYYTFHFLNLTSRQSLNTVNDTVWKFCQKPWKLVEVSYPGQERWLRDYCASGLYILVLLLEGYKFSEETWPNIQFQKQAGDTDIGWTLGFMLNLTGMIPAEAPTHWRAQSYSIWTAGVVFAVLTLVAILGAAAIQIFWTQD
What is the function of this protein?
Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity.  Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides.  Has activity toward ATP, ADP, UTP and UDP, but not toward AMP.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 8, E-NTPDase 8, NTPDase 8, NTPDase8.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SC13B_ARATH
Sequence: MPGQKIETGHEDIVHDVQMDYYGKRIATASSDCTIKITGVSNNGGSQQLATLTGHRGPVWEVAWAHPKYGSILASCSYDGQVILWKEGNQNQWTQDHVFTDHKSSVNSIAWAPHDIGLSLACGSSDGNISVFTARADGGWDTSRIDQAHPVGVTSVSWAPATAPGALVSSGLLDPVYKLASGGCDNTVKVWKLANGSWKMDCFPALQKHTDWVRDVAWAPNLGLPKSTIASGSQDGKVIIWTVGKEGEQWEGKVLKDFMTPVWRVSWSLTGNLLAVSDGNNNVTVWKEAVDGEWEQVTAVEP
What is the function of this protein?
Required for protein transport from the endoplasmic reticulum to the Golgi apparatus.
What are the official names of this protein?
Protein transport protein SEC13 homolog B, SEC13-like protein B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Golgi apparatus. Endoplasmic reticulum. Nucleus envelope. Nucleus, nuclear pore complex.
Protein: MOGT1_XENTR
Sequence: MKLEFAPINIPLARRLQTTAVFQWVFSFLLLAQCCIGIFLSLVLARLWLILALYVLWLYLDWETPQAGGRRWEWVRNWTVWKYFKDYFPIRLVKTCDLDPQHNYIMGFHPHGVLVAGAFGNFCTNYTGFKELFPGLTPYLHILPFWFRCPFFREYAMCVGLVSATKKSVNHVLSKENGGNISIIVIGGAEESLDAHPGSLILHILKRKGFIKVAFKQGAHLVPVFSFGENELFQQVPNPKGSFLRCVQERLQKIMGFAMPLFHARGIFQYSFGLMPYRMPIHTVVGRPIPVKQTSHPTQEEIESLHQQYLSALRDLFEEHKERYGIPEHESLIFT
What is the function of this protein?
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA.  Probably not involved in absorption of dietary fat in the small intestine.
What are the official names of this protein?
2-acylglycerol O-acyltransferase 1, Acyl-CoA:monoacylglycerol acyltransferase 1, MGAT1, Monoacylglycerol O-acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NH153_CAEEL
Sequence: MTPPQKSKPKRNRRKIYKILPQNQCPSVCQICRNPAIGYHYEVPSCNGCKTFFRRTIITGRKFKCFKVSNCLDGNDVIDTSKRVCRACRFEKCVQAGMNPMAIQAEAKTDEGEELKKLIAKKFENGEKLNDGTVFFNVHDRLNQILGKLIKIETKLEKVHDNGMPMGFLDQRDLSTALSSKVIYNNMEIPSMSYTPVKISKNTGLPKRRSRNFVHSSCLASIEYSKTFDFSSAIDISSKIILLKNTALSCANLTNAYTTFRKLKSDTLLYPDGSIYGPPRRKNGPLIEKQRSFLQNTLISFMTNNVDKTEYILLKAIVLCNPAIIDLPYADSKHIQREREVYAQCLFRYCLLQHGTLHGPARFSALLSIFNVLENQQKEQKDYYLYIKLIHSQKHKDPEVLKKKCISVIYDQIMD
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-153.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATC_BARBK
Sequence: MSVNDKTIKRIAHLARIAIHDNETERITKKFNAILDFAKQLDEIDVTGVDPLISVIPMTLRTREDSITDGNKAADIVANAPVTEENFFLVSKIVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RPOE_BACHK
Sequence: MDFKQYSPEELKECSMIEVVHSVLGDKRQATTFNELVQEIAQVLGLSQEQVNAKIAQFYTDLNIDGRFINLGENRWGLRSWYPYEQIDEEILPQPKPKKKRKVEDDGFDDYIEEDEDFDDADVTEDEDDDVEDLDKVLEDEDGDDDDLDDLDEDDDDFAEEELEYDETEEEEEEEL
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: INS_PIAME
Sequence: NAGAPQHLCGSHLVDALYLVCGPSGFFYNPKGIVEQCCHKPCSIFDLQNYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOBA_STAAN
Sequence: MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNIYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAN9_ORYSJ
Sequence: MGSKRRVILLPTLGVVVLAIAAAVLLHAGEAADVANGQFARASGTRFTVGGRPFYSNGFNAYWLMYMASDPGDRSKAAGVLQQAASLRATLVRTWAFSDGGYRPLQKSPGVYNEDMFMGLDFVIAEAKKRGLYLILSLVNNWDGFGGKKQYVQWARDQGHNLGSDDDFFRSDVTKQFYKNHAVLTRVNKITGVAYKDDPTIFAWELINEPRCQSDLSGKTLQAWVTEMAGYVKSVDPNHMVEIGLEGFYGESMHKNFNPGYTVGTDFIANNLVPAVDFATIHSYPDQWVSGASSDEQVAFMRKWMADHIRDSAAVLRKPLLVTEFGWSARSNGYTVAARDAYFRTVYDAVYASAREGGACAGGLFWQVMAPGMESWTDGYEVVLERSKSTADVVAHQCARIAGLSPA
What are the official names of this protein?
Putative mannan endo-1,4-beta-mannosidase 9, Beta-mannanase 9, Endo-beta-1,4-mannanase 9, OsMANP, OsMan9.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: AGAL_BACSU
Sequence: MKKITFIGAGSTIFAKNVLGDCLLTEALNGFEFALYDIDPKRLQESQLMLENLRDRYNPSVAINSYDDRKLALQNAGYVINAIQVGGYKPSTVIDFEIPKRYGLRQTIADTVGIGGIFRSLRTIPVLFDIAKDMEEMCPDAWFLNYTNPMATLTGAMLRYTNIKTIGLCHSVQVCTKDLFKALGMEHDGIEERIAGINHMAWLLEVKKDGTDLYPEIKRRAKEKQKTKHHDMVRFELMDKFGYYVTESSEHNAEYHPYFIKRNYPELISELQIPLDEYPRRCVKQIENWEKMRDDIVNNKNLTHERSKEYGSRIIEAMETNEPFTFGGNVLNTGLITNLPSKAVVEVTCVADRKKITPCFAGELPEQLAALNRTNINTQLMTIEAAVTRKKEAVYQAAMLDPHTSAELSMKDIISMCDDLFAAHGDWLPEYK
What is the function of this protein?
Catalyzes the hydrolysis of melibiose and alpha-galactosides of the raffinose family of oligosaccharides (RFOs) such as raffinose and stachyose.  Cannot act on polymeric substrates such as locust bean gum.
What are the official names of this protein?
Alpha-galactosidase, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_ACTP2
Sequence: MKKLVILGSTGSIGKSTLSVVEQNKTEYEVFGLVGGKNVELMAAQCLLFQPKFAALDDENAAKALEEQLRQLNVKTEVLSGQKAICELSAHPEVDMVMAAIVGAAGLLPTLSAVKAGKKVLLANKESLVTCGQIFIDEARKSGAQLLPVDSEHNAIFQSLPPDAQQKVGFCPLAELGVSKIILTGSGGPFRVKPLDEFAAITPAQAVAHPNWSMGKKISVDSATMMNKGLEYIEARWLFNASAEEMEIIIHPQSIIHSMVRYIDGSVIAQMGNPDMCTPIAHTMAYPKRINAGVAPLDFFKLKELTFIEPDFARYPNLKLAIDAFAEGQYATTAMNAANEVAVEAFLNERIRFIDIVNVNRTVVENIAPVQVKEIADVLHIDKLARELAEQAVINL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: YITT_BACSU
Sequence: MVLDQTKKLLIVIIGALLNAAGLNLFLIPADVYASGFTGVAQLLSSVVDQYAPFYISTGTLLFLLNIPVGILGWLKVGKSFTVYSILSVALTTLFMGILPETSLSHDILLNAVFGGVISAVGIGLTLKYGASTGGLDIVAMVLAKWKDKPVGTYFFILNGIIILTAGLLQGWEKALYTLVTLYVTTRVIDAIHTRHMKLTAMIVTKKADEIKEAIYGKMVRGITTVPAKGAFTNEQKEMMIIVITRYELYDLEKIVKEVDPKAFTNIVQTTGIFGFFRKD
What are the official names of this protein?
UPF0750 membrane protein YitT.
What is the protein family that this protein belongs to?
Belongs to the UPF0750 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CEGT_GIBZE
Sequence: MYSFIECIAGALFVLGCVVVTLVVIGVRALLYNFRNRPAPPLSSQLGQNAPHVTIIRPVKGLEPRLYDCIAASFRQDYPQDKVSIRLCLEDDTDPAYPVLQKVIEDFPTIDARIMLEKEDHVLSETVNMGPNPKIRNLSRAYREAKGDIVWIIDCNIWMAKGVLGRMVDKLMGYRVGGAAKPYKFVHQLPIVVDLMDFSTSLAAEGRSLLDASPEEDHPTEDLGAEEFPKVMSHGGGRIDEMFMTTSHAKFYSAINTLRAAPCAVGKSNMFRKSQLDQATDAILNPKLDQSKNLPTGVDYFSHNICEDHLIGEALWTTDFPGYKSHGLVWGDIAVQPVSGMSVQAYTARRSRWLRARKYTVLSATILEPFTECFLFATYMSLAMTTIPVLSQNLGIPKTWNATAIAWFTITTLWMLIDYIGYLRLHSGVTMEVDEHTPYFAKGFKNTGGIKRRPFLEFLAAWIGREGLAFPVWAYAVVFGNTVNWRGRLFYIHWDTTVDAVEPREERTREVRTPELERGPSRNKHRVD
What is the function of this protein?
Catalyzes the final step in the biosynthesis of the membrane lipid glucosylceramide (GluCer), the transfer of glucose to ceramide (Probable).  Glucosylceramides play important roles in growth, differentiation and pathogenicity.  Contribution to fungal pathogenesis is host-dependent (PubMed:17908205).
What are the official names of this protein?
Ceramide glucosyltransferase, GLCT-1, Glucosylceramide synthase, GCS, UDP-glucose ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PAM68_ARATH
Sequence: MASVPCSFKLSAHRRSSSKLDGNNKQCSSLVERLRDKTKSQVPKSITCINRLEISRIAPLHATMNSPKGFGPPPKKTKKSKKPKPGNQSDEDDDDEDEDDDDEEDERERGVIPEIVTNRMISRMGFTVGLPLFIGLLFFPFFYYLKVGLKVDVPTWVPFIVSFVFFGTALAGVSYGIVSSSWDPLREGSLLGWNEAKKNWPVFWQSFWNSSDKR
What is the function of this protein?
Involved in early steps in photosystem II (PSII) biogenesis and in maturation and stability of newly synthesized psbA protein.
What are the official names of this protein?
Protein PAM68, chloroplastic, PHOTOSYNTHESIS AFFECTED MUTANT 68.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DNLJ_RHIE6
Sequence: MSTEGSAVDTLTIEEAAAELERLAKEIAHHDALYHGKDQPEISDADYDALKRRNDALEARFPELIREDSPSRHVGAAPSVTFSPVVHARPMLSLDNTFSQEDVQDFVAGVYRFLGRLPDQSIAFTAEPKIDGLSMSIRYENGRLVTAATRGDGTTGENVTANIRTIAEIPNELPKGVPAVVEIRGEVYMAKSDFLALNRQMEAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLKFFAYAWGEMAEMPADTQFGMVQTFKDWGFPVNPLMKRLNSVADILAHYDEIGLERPDLDYDIDGVVYKVDSLELQQRLGFRSRSPRWATAHKFPAEQAFTEVEKIEIQVGRTGALTPVARLKPITVGGVVVTNATLHNEDYIKGIGNSGERIRPEEHDIREGDTVIVQRAGDVIPQILDVVMEKRAADARSYEFPKTCPVCGSHAVREVNEKTGKTDSVRRCTGGFICRAQATEHLKHFVSRNAFDIEGLGSKQVDFFFENEDPSLQIRTAPEIFTLEKRQQDSLTKLENIDGFGKVSVGKLYAAINERRSIALHRFIYALGIRHVGETTAKLLARSYGTYEAFATAMKEAAPLSGEAWTDLNAIEGIGEVVARAMVEFYKEPRNVEVIGRLLDEVTPAEAEQPVTAGSPVAGKTVVFTGSLEKFTRDEAKARAESLGAKVAGSVSKKTDIVVAGPGAGSKLDKARELGVQTMDEDEWLALISG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: AMPA_ROSCS
Sequence: MRVTVTAGDPLSTATDLLVLGLWEEESLPSPLDDLIEPGDWSGKAKQTLLIYPRGALPARRVLLIGLGKRSAPDLDQMREVAAIATQRARELKVDRFAFVIPVLSEQTPETVAAAITEGSLLGSYRFLEYKSDLKPEDRREVDELTLLAPVDAVDEAARGIARGGAVARGVNLARDLANLPPNDLTPARLAERARELAVAFDLPITVLGPAEMREQGFGGILAVGQGSVNEPRFIVIDYGAQYADAPTICLAGKGMTFDSGGISIKPAENMDAMKMDMSGAAAVLGALHAIAELRLPLHVVALIGAAENMPGGSAYRPGDILKTLSGKMIEVLNTDAEGRIVLADVLTYAQRYHPSAIIDLATLTGAISVALGPHAIGLFANDDALAQRLVRAGEAAGERAWQLPLWQPYREMVKSEIADVRNATGRQAGAITAAAFLNAFVGDYPWAHLDIAGTAWTDSKPKAYQPKGATGVGVRLLLQALRDWTQA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.