PharMolix/UniProtQA huggingface dataset:
Protein: MTRE_META3
Sequence: MDPTLLALGALALSGAAATVAGCAEDLESDVGSQSNPNSQVQLGPQMGNIHRYFNKAISGEPVSYGLYVAAAGATAWALMGMNLNPILAIIVGSAVAALVHGAYSVSAFLGRIVGQSKNFGQPVYMDVMMGHLGPIVGHGFIAVFCMLFAAYLAVNALGNPFPLPLVALIFGITVGAIGSSTGDVHYGAEREYQKYAFGGGIPVANQGDIDIMAETGIRNGLDSSYFCSKLGGPLTGLAFGLIIFLDGWRSILGNIIGGDLITKAAIAIVVGLIVVITTLLLNRKIEVYARNKFGPYTDR
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit E, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E.
What is the protein family that this protein belongs to?
Belongs to the MtrE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MOAC_GEOSW
Sequence: MSSFTHFNEQGRAKMVDITEKEDTIRVAVAQTSVTVNKEIYEKMTNRMIEKGDVLAVAQVAGIMAAKKTSDLIPMCHPLMLKGVDIQFAWHVEEEKALYQLLITVTVKTKGSTGVEMEALTAASVCALTVYDMCKALDKGMVIGPTYLVEKSGGKSGHYQRENSSVGGFANEQ
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RS5_BACHK
Sequence: MHRIDPSKLELEERVVTINRVAKVVKGGRRFRFAALVVVGDKNGHVGFGTGKAQEVPDAIRKAIEDAKKNLIAVPLVGTTIPHTINGHFGAGEVFLKPAAEGTGVIAGGPVRAVLELAGVQDILSKSLGSNTPINMIRATVNGLSELKRAEDVAKLRGKSVEELLG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RL20_PROM3
Sequence: MARVKRGNVARKRRNKILRLARGFQGSNGSLFRTANQRVMKALCNAYRDRRRRKRDFRRLWIARINAAARINGVSYSRLIGDLKKADVRINRKMLAQLAVMDPKSFTSVVTSAKS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: Y2692_EDWI9
Sequence: MSSAPTPHVAWFRLFQRGQIYMKTWPNEKRLAPVFPENRVTRATRFAIRFMPPIAMFTLCWQIALGGQLGPAIATALFACSLPMQGLWWLGKRAVTPLPPTLLQWFHQLRDKLQASGIALAPVDGAPTYQSLAELLRRCCKQLDKTFLDDI
What are the official names of this protein?
UPF0208 membrane protein NT01EI_2692.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRIB_ECOL5
Sequence: MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).  During primosome assembly it facilitates the complex formation between PriA and DnaT.
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: ATG15_PICAN
Sequence: MGNPTLMRWPVTRILVLGLVVTVLYKAMAIYSSRRAPVQVCFTSPSSAFKIKHIFHNAADGRTHKRLDIDDEFLSIYNSARSQMAHIEDMDLFTVSPFEQELVIRHTEGQTVRLADRSPDFVESYLDYALENGPASRMIEFDWQQESLLIPNMSDKETIVSLALMSSDAYVGLPTDADWNDVGDKYNESERFGWENGGVRGHVFTDPEETIVIISIKGTSAAGLNTGGDGQTVEQDKTNDNLLFSCCCARVSSLWKTVCDCYEESYTCNQNCLEQELRRPDRYYKAVLEIYRNVTHMYPESEIWVTGHSLGGSLSSLLGRTFGLPAVSFEAVGELLATRRLHLPMPPGLPEEMENIWHVGNTADPIFMGVCNGASSTCSLAGYALETQCHSGKKCVYDVVNDLGWHVNLLNHRIRTIISDVLMVYNDTAECVKPPPCYDCYNWRFVDHSGDRYRTTASSPSPIPSDPPGRRCLKRTWYGRCYEWADDPSAVKTTFATSTIYRKTSDISTSTHTGGNTTCIRRSWLGYCLEYGPELR
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase ATG15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: SYGA_YERPE
Sequence: MQKFDTKTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRAIGPEPIAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVIIKPSPDNIQELYLGSLKELGLDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLIWCDGPLGTTTYGDIYHQNEVEQSTYNFEYADVDFLFSCFEQYEKEAQSLLALETPLPLPAYERILKAGHTFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCKKNQN
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_EUGAN
Sequence: YRLTYYTPDYQVAETDILAAFRMTPQPGVPAEECGAAVAAESSTGTWTTVWTDGLTQLDKYKGRCYDLEPVPGENNQYIAYVAYPIDLFEEGSVTNLLTSIVGNVFGFKALRALRLEDLRIPPAYVKTFWGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQSFMRWRDRFLFCAEAIYKAQSETGEIKGHYLNATAGTCEEMYKRANYAAQIGVPIVMHDYLTGGFTANTSLAMFCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKTLRMSGGDHLHSGTVVGKLEGEREVTLGFVDLMRDPYVEKDRSRGIYFTQDWVGLGGTIPVASGGIHVWHMPALTEIFGDDACLQFGGGTLGHPWGNAPGAAANRVASEACVQARNEGRDLSREGGDVIREACKWSPEL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYP_STRPM
Sequence: MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLPLANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNSDFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAVTPARTDLDRWVVLDKSIASMDDIPKEVLEDIKAELAAWMISGEDTIAYSTESSYAANLEMATNEYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVGNDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLTNAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFKLGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRYAWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKFSDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBXA_DICDI
Sequence: MQYVNGNDISSQSIHEVLELAFSTKIPWTKLEYESSEKHIIHSYSSHERGIYLSKGVAEFNISPENMYELLLDISSRSKWDFHCREAHIIEEYDHLNHIIHLNFTNPLISNLDMNLYRSCKYDPQERLFVIAMRSIELEDGDVDQFECLPNGWVIQGLRGQKDKCKMTFVQQCDLRDIELQRIPGYKSFNSKERLEDFQFLTLFPATVSGRLAKIFESIELYISNNVKDIETKDIRISIMEKAEKEVNEMFGTTNPDYGWKIYLKKLDMEILIKKTTSGYYMIGKGSFSSRYSPELLADVLYQKNPFEWDTFYDKTKLVESINSSIREVEVHYRMWRNTITMRLLQSVKKGPGNFSSVHWRSICSPNYQVADGIEVHYLPTALLNYGLGDGSFTSFLAAIEVKGYPTPWEEEMVTKMFAARIISNQNSIINHVNKLTGGSEMIRELPVIPSVQHHCGDVGSHIGTPQVYNAMVENFADILLDEGNKDGNVVSSKNKRKRNKNNENKNNNNDNIIDEEIEQEEENIEKDQQQTQQQQTQKQQQQQQQQQKTQQQPQQQQQQPQEQQQNHSQLKKEIKPTRPSIRFTYLLSNSSSGQRPIAWYESKKQPFLFLVSDSSERKGKIQRKTYYFSNSGFDNLPEEVVQIIFSNLSAINIVNLSLVCKRFKMATDSPILWKNLYKSNPLFHKKTPKRKQIIHSNLSNDENKVNSNSGDSADGSSSQEEEEQQQQNQQQNQQQNQQQQQQQTFDLSNINLNDPISLLMVFTNGIIPQNLSPTEIINVGGIVSQIDLNDLSNVETLIQQLPHQVLSLIQMNTLDAKIQHLSMISGMPATIGQESPINKNSSDNPKPNAYNKRDNNSYIPDEEFINWKSHYTEKHKQSKRWVNMEPIRITPLKGHNRAIKAVKSEGNSAITVSTEKKIKFWNLNTGQCIGDYEGESGVLSVEYDHTQKSSCIWPLSDYTKVHIGHKNGTVTMVDFIEQPIEVIHTSRPTNLADGFDFTFPGKYLIWEHTIIHYWDVETSTLLWNELNAHTKKITQSKIVAQHELSNKGIVFTTSSDKSAKVWDLTNGTCINTLVGHSYAVNCIEPIGDYMALTGSTDKTLKLWDLRQASTFISSYSTKHTGPIRCISYQEKNGIVLSGSDDGSIIAFNLDNWNLSNISVVKKPIFNNVIGNIGTTTTTTTTTTTTTTTTTSTTNNTNVPEIPKINLGTFKDSKRLHNHESAVTCIESDEAGFISGSQNGLVLRWDF
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  May target the cAMP phosphodiesterase regA for degradation leading to an increase in cAMP and PKA activity.  Promotes development of prestalk cells as opposed to prespores within the developing fruiting body.  Required for culmination and fruiting body development.
What are the official names of this protein?
F-box/WD repeat-containing protein A, F-box protein A, Protein cheater A.
Protein: THIE_BACVZ
Sequence: MTRISREMMKDMLSVYFIMGSNNTSADPVSVVEKAIEGGATLFQFREKGSGSLTGEERLLFAKRVQDVCRQAGIPFIINDDVELALRLEADGVHIGQDDADAEETRAAIGDMILGVSAHNVSEVKRAEAAGADYVGMGPVYPTETKKDAEAVQGVTLIEEVRRQGITIPIVGIGGITADNAAPVIEAGADGVSMISAISQAEDPKAAARKFSEEIRRSKAGLSR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: HELD2_ASPFU
Sequence: MEGLNISNQVFDLSPLDIIPSHLYITNAFFYENKTPGPRPFMQSSLLKESLYRALQNFPILLGHVRRHRRNAMQIVVDCDNLNLPLYEEQTHPQLHFRHLKDHQFHRDVWPKDANIIDPRASPNGELLQVHVHRLAEESGVVMVVRIAHCAVDAKGFVDFMQSWGWFARNHSHPEGDSWPRLLADRRVMYEYLPPDVQPAAPRSMWHPASWLLGLLSTLVVLFLGLYKRLLGDKTPPDEIESHLFSVPPHTLDRLRYTATCIDPSSRVSDHDIITALFTLAFAHTKHLLTCRTQTVTAIVPCDFRHRIGVPSNFTGSCAIGLYVSIPGSLLQTPLTAESVARAALLSRAVVDTADKVTIQTFIRRALRAIAFVGDKVNVLYATMVSQAFSNQSRLGFYEVDFGAGGPVMVAPMAYSNTVAVICPAPGPGGDGVGVRVFLTLRPEVMRMLLAKGFLDEFTDMIY
What is the function of this protein?
Acyltransferase; part of the gene cluster that mediates the biosynthesis of helvolic acid, an antibacterial nortriterpenoid (PubMed:19415934, PubMed:19216560, PubMed:29158519).  Protostadienol synthase helA cyclizes (3S)-oxidosqualene to (17Z)-protosta-17(20),24-dien-3-beta-ol (protostadienol)(PubMed:19415934, PubMed:19216560, PubMed:29158519).  The synthesis of protostadienol is followed by several steps of monooxygenation, dehydrogenation, and acyl transfer to yield the final helvolic acid (PubMed:19216560).  Following the cyclization to the tetracyclic protostadienol by helA, cytochrome P450 monooxygenases helB1-mediated and helB2-mediated oxidation at C-4 and C-16, acyltransferase helD2-dependent acetylation of 16-OH, oxidation of C-21 by cytochrome P450 monooxygenase helB4, and short chain dehydrogenase helC-dependent oxidative decarboxylation yield the fusidane skeleton (PubMed:29158519).  This intermediate is further modified in three additional steps mediated by the cytochrome P450 monooxygenase helB3, the acyltransferase helD1, and the 3-ketosteroid 1-dehydrogenase helE to give helvolic acid (PubMed:19415934, PubMed:19216560, PubMed:29158519).  Compared with the late stages in the biosynthesis of helvolic acid, enzymes involved in the early stage modifications act in a relatively strict order (PubMed:29158519).  The hydroxylation of C-16 by helB1 and subsequent acetylation by helD2 should occur before the helB3-mediated oxidation of C-21 (PubMed:29158519).  C-4 demethylation in fusidane-type antibiotics proceeds in an unusual manner though it is also achieved by oxidative decarboxylation (PubMed:19415934, PubMed:29158519).  The methyl group at C-4 beta position is oxidized by helB1 and subsequently removed by the short chain dehydrogenase helC (PubMed:19415934, PubMed:29158519).
What are the official names of this protein?
Acyltransferase helD2, Helvolic acid biosynthesis cluster protein D2.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: RL31_GEODF
Sequence: MREGIHPKYNEVTVKCLCGNTFQTRSTKPEISTEICSACHPFFTGKQKLVDTAGRVERFKKRYGM
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RECX_THEP1
Sequence: MDYYQWRKKNRRRKRNLQTKKPLNYALKLLKYRVRFEDELRERLKKQGFADEEVESTINTLKKQGYLDDEKAAYLFALDEMRLKLFGPRVVRMKLKSLGVDEEIIERAIEKALEEIDFHEELKRLKGRFKDRWELRDYLYRRGFDPSLIEEILNKIDGGEE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_CHLT2
Sequence: MEKRKDTKTTLAKASDDRNKAWYVVNAEGKTLGRLSSEVAKILRGKHKVTFTPHVAMGDGVIVINAEKVRLTGAKRAQKVYHYYTGFISGMREVPFENMIARKPAYVIEHAVKGMLPKTKLGRRQMKSLRVLKGSSYAQYEAIKPIVLDA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS7_ECOSM
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: LAP5_ARTOC
Sequence: MKVLAALALSALALAKPTPPMPGMSLIQTGPQETRWVTDAEKLELTMNNVGFFDITDMPVTASSVTKPKSYAFPGNVSHQADVKPLLGKLSSDHLMSNLQKFSDFPNRYYQADTGVQSAEWVLSQVQGVIGKIQGAKAEKIEHKWKQPSIRAIIPGKSEKIVVVGAHQDSINGQNPKAAAPGADDNGSGSMTILEALTALVSDQKIAGGQATNTIEFHWYAGEEAGLLGSQAVFQQYKQAGKEVVAMLNQDMTGYGKTMGIITDNSDSALTTFTKMILDTYTTAKYADSECGYACSDHASANKAGYPSAFVYEAVLGQDNPAIHSPDDTIDKLDPAKMLEHAKLVVGFAYELAFANL
What is the function of this protein?
Probable extracellular aminopeptidase which contributes to pathogenicity.
What are the official names of this protein?
Probable leucine aminopeptidase MCYG_04170.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ANO7_HUMAN
Sequence: MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRAQEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPRIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEVLFGTNGTKDEQPEGSELSSHWTPFTVPKASQLQQ
What is the function of this protein?
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity).  Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:22075693).  May play a role in cell-cell interactions (PubMed:17308099).
What are the official names of this protein?
Anoctamin-7, Dresden transmembrane protein of the prostate, D-TMPP, IPCA-5, New gene expressed in prostate, Prostate cancer-associated protein 5, Transmembrane protein 16G.
What is the protein family that this protein belongs to?
Belongs to the anoctamin family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Multi-pass membrane protein. Cell junction. Endoplasmic reticulum. Note=Concentrates at sites of cell-cell contact (PubMed:17308099). Shows an intracellular localization according to PubMed:22075693 and PubMed:20056604. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytosol.
Protein: RL22_GEOSE
Sequence: MQAKAVARTVRIAPRKARLVIDLIRGKEVGERFAILRHTPKAASPIIEKVLKSAVANAEHNYDMDVNNLVISQAYVDEGPTLKRFRPRAMGRASAINKRTSHITIVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y597_TREPA
Sequence: MRRILSYKDEDIDAHMVMRRSLLVTNLGKGALVGHRVQQSQVYRMSRAYALPKVAAITSNGVVSVNYDGSVSWYEGDGATLKATEFIRTEDF
What are the official names of this protein?
Uncharacterized protein TP_0597.
Protein: YFGG_ECOLI
Sequence: MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHHQSKKEAQQSTLSVESPVQR
What are the official names of this protein?
Protein YfgG.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NADA_BACAC
Sequence: MSILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAAGDSLQLAQVAASNKEAKYIVFCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQTERAWEELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATVTSSNAKQMVSWAFTQKERLVFLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKNIENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNRIIQQHPDKEIVSLNPFMCPCLTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLALNRMLERV
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_BURM9
Sequence: MDFSIKGCDWSKGTANGFLTGKSDCIVLGVFEAQTLSGAALDIDEATKGLVSRVIKAGDIDGKLGKTLFLHEVSGIGASRVLLVGLGRQDAFSQKAYGDAAKVAWRALLGTKVVQVTFTLAQLPVPERASDWGVRAAILALRNETYKFTQMKSKPDAGAPALKRVVFSVDPADDKAAKVAAKQAVALANGMDLTRDLGNLPGNVCTPTYLANTAKKIAKDWGLKVDVLGLKQIQALKMGSFLSVAKGSVEPPQFIVLQYRGAAAKAAPVVLVGKGITFDSGGISLKPGEGMDEMKYDMCGAGSVLGTMRAVAEMGLKVNVVAIVPTCENMPAGNANKPGDIVTSMKGLTIEVLNTDAEGRLILCDALTYAERFKPAAVIDVATLTGACIIALGHHNTGLFSKDDALAGELLDASREAGDPAWRLPLDDEYQDQLKSNFADLANIGGRPAGSVTAACFLSRFAENYPWAHLDIAGTAWKSGAAKGATGRPVPLLAQFLIDRAGA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_XYLFT
Sequence: MNFVTTLTYLLPHRMLSSLARHVAYCQHPLIKQWLIDTVIAKFDVNLSEAAEPDAHAYPSFNAFFTRSLKAGIRPPDPNPDTLLMPADGRISQLGPIREGRIFQAKGQSFTATELLGDTAAASAFTNGLFATVYLSPRDYHRVHMPCTGQLLKTVHVPGRLFSVGPDAVRQIPRLFARNERLVCHFDTTFGPMVLVMVGALLVSGVETVWGGVEIPAYGDRITYKDYQGRNIAIERFAEMARFNYGSTVIVLLPPNVLTLAPHLTAESPVTLGQALAHRLSLNHSTQAPTQEK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NO51_SOYBN
Sequence: MEKMRVIVITVFLFIGAAIAEDVGIGLLSEAEAYVSPKLKKFITPCTSHVGETCSTTSSSGSEALMQNQGGLALCLFDSMERCLVDHGAQLYQTSVTNLQVEPSEVFPRKNNPQGGRKSKLDDHQVQPLSFRLPPFRLPPMPKLGPTSPIIRTIPSPPIAPRDLSLIETIQLRTALRTCTHVTARTCLTAPNVATSDLEACLTPSMNQCIYPRGAEYGSPPIRA
What is the function of this protein?
Involved in the infection process during the plant-rhizobium interaction.
What are the official names of this protein?
Nodulin-C51.
What is the protein family that this protein belongs to?
Belongs to the nodulin 20 family.
Protein: TRI58_HUMAN
Sequence: MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFICDATPLILPPTTIAGSGNWASRDHLDPASDVRDDHL
What is the function of this protein?
E3 ubiquitin ligase induced during late erythropoiesis.  Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex.  May participate in the erythroblast enucleation process through regulation of nuclear polarization.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM58, Protein BIA2, RING-type E3 ubiquitin transferase TRIM58, Tripartite motif-containing protein 58.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: YABA_BREBN
Sequence: MDKREIFVKMASIEERIGDLYKEIGELKDVIVVLMEENAQLLVENQHLRNRLDRKKTGSQAKQKGTSPVAKEKAKKAVVGEGYDNLARLYAEGFHICNVHFGSLRKEGDCLFCLSFLSGGPQK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: TRP1_EUSSE
Sequence: GPSGFLGMR
What are the official names of this protein?
Tachykinin-related peptide 1, TKRP-1.
What are the subcellular locations of this protein?
Secreted.