PharMolix/UniProtQA huggingface dataset:
Protein: SUV3_RAT
Sequence: MSLPRCALLWARLPAGRGAGPRAAPCSALRALVGSFPGASGRVPCLAASSSASGGSKAPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKILDKFYKRQEIQKLSADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFSAAHVDDLFPFFLRHAKQIFPVLECKDDLRQISDLRRPPNWYPEARAIQRKIIFHSGPTNSGKTYHAIQRYLSATSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERLTVEPEGKQATHVSCTVEMCNVATPYEVAVIDEIQMIRDPARGWAWTRALLGLCAEEVHLCGESAAIDLVTELLYTTGEEVEVQKYERLTPISVLDRALESLDNLRPGDCIVCFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQARKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGEKELEPITTSQALQIAGRAGRFSSHFKEGEVTTMHRDDLALLKEILNRPVDPIQAAGLHPTAEQIEMFAYHLPETTLSNLIDIFVDFAQVDGQYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLLPPKNIKDLMDLEAVHDVFDLYLWLSYRFIDMFPDSSFVRSLQKELDVIIQEGVHNITKLIKISESHKLLNLEPSGSQSRLPGASKSPARRTRGTKTGNKAAEPPSPSDKELPLASRLVQQGLLTADMLKQLQKEWLTQRPEQGKEKVGTRRKKKDPNSD
What is the function of this protein?
Major helicase player in mitochondrial RNA metabolism.  Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner.  Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules.  ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction.  Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates.  Also implicated in recombination and chromatin maintenance pathways.  May protect cells from apoptosis.  Associates with mitochondrial DNA.
What are the official names of this protein?
ATP-dependent RNA helicase SUPV3L1, mitochondrial, Suppressor of var1 3-like protein 1, SUV3-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
Protein: MSRA1_SYNY3
Sequence: MGFFDLFGKKTAMVAPNEALPGRSATMPVPDKHFVNGNPLKAPFPQGMETALFGLGCFWGAERKFWQIPGVYSTAVGYAAGYTPNPTYQEVCTGMTGHNEVVLVAFDPQQVSYDQLLKVFWESHNPTQGMRQGNDVGTQYRSGIYTYSEAQQQAALASKQAYQQALQQAGYGEITTEILPAPDFYYAEDYHQQYLAKNPNGYCGLGGTNVACPIGTEVSLGA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA 1, Protein-methionine-S-oxide reductase 1, Peptide-methionine (S)-S-oxide reductase 1, Peptide Met(O) reductase 1.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: SIKE1_HUMAN
Sequence: MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKENSMDTASQAIK
What is the function of this protein?
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3.  Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter.  May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and RIGI.  Does not inhibit NF-kappa-B activation pathways.
What are the official names of this protein?
Suppressor of IKBKE 1, Suppressor of IKK-epsilon.
What is the protein family that this protein belongs to?
Belongs to the SIKE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNN3_RAT
Sequence: MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQPPPPSAPPAVPQQPPGPLLQPQPPQLQQQQQQQQQQQQQQQQQQQAPLHPLPQLAQLQSQLVHPGLLHSSPTAFRAPNSANSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEGQPLQLFSPSNPPEIIISSREDNHAHQTLLHHPNATHNHQHAGTTAGSTTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRGVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLTAFVEARGISVAVGTSHAPPSDSPIGISSTSFPTPYTSSSSC
What is the function of this protein?
Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:11533126, PubMed:11245600).  Activation is followed by membrane hyperpolarization (PubMed:11533126).  Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization (PubMed:11533126).
What are the official names of this protein?
Small conductance calcium-activated potassium channel protein 3, SK3, SKCa 3, SKCa3, KCa2.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS8_BURCJ
Sequence: MSMSDPIADMLTRIRNAQMVEKVSVAMPSSKVKVAIAQVLKDEGYIDDFAVKAEGAKSELNIALKYYAGRPVIERLERVSKPGLRVYRGRNDIPQVMNGLGVAIVSTPKGVMTDRKARATGVGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NRAM1_CEREL
Sequence: MPGDMGPPKQGGTRYGSISSPPSPGPQQAPPGGTYLSEKIPIPDTESGAFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAIAFSLLSAGRIPLWGGVLITIVDTFFFLFLDNYGLRKLEAFFGFLITIMALTFGYEYVVARPAQGALLQGLFLPSCAGCGQPELLQAVGIVGAIIMPHNIYLHSSLVKSREVDRSRRADIREANMYFLIEATIALSVSFLINLFVMAVFGQAFYKQTNQAAFNICANSSLHDYATIFPRNNLTVAVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQEFANGLVSKVISSSIMVLVCAVNLYFVISYVPSLPHPDYFSLVALLAAAYLGLTTYLVWTCLITQGATLLAHSSHQRFLYGLPEEDQENGRTSG
What is the function of this protein?
Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens.  Macrophage-specific membrane transport function.  Controls natural resistance to infection with intracellular parasites.  Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes (By similarity).
What are the official names of this protein?
Natural resistance-associated macrophage protein 1, NRAMP 1, Solute carrier family 11 member 1.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PRMA_PROM3
Sequence: MNSASACCWWRLALPIADELEESLIWKLTELGISRIAVQHVPEKAERTLLAWLPSSEWSESDRDQLMVNLRPLAEPFGLQLANPTWCEVADEDWSLNWKQHWQSDPVGQRLLILPAWLDLPQEYADRLVVRMDPGSAFGTGSHPSTRLCLEALEKNPPLGLRVADLGCGSGVLGFAALGFGARQVLAADTDSQAVCASRANAELNQLDLDRFRVVHGSVDALSAQLQGEVVDLLLCNILAPVIEALASSFDQLLSANGRCLLSGLLVDQAPRLQVVLEALGWRVNSLTVQGCWGLLDVSKR
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NA2G3_STIGI
Sequence: MAYLKIVLVALMLVVAVSAMRLSDQEDQDISVAKRAACKCDDDGPDIRSATLTGTVDLGSCNEGWEKCASFYTILADCCRRPRG
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction.
What are the official names of this protein?
Delta-stichotoxin-Sgt3a, Delta-SHTX-Sgt3a, Gigantoxin III, Gigt III, Gigantoxin-3.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: YSL11_ORYSJ
Sequence: MASAAANNSSSAAYDAAETGGLLRRRNTTAAARGNAGEEEEEAEAVAPSVEQAFADKPVPSWREQLTVRAFVVGFLLSIMFNIIVMKLSLTTGVIPSLNVSASLLGFFLVRLWTAAIERVGFLKQPFTRQENTVIQTCVVSAYGVAFSGGFGSYLFGMSETIAKQATEANDPMNIKNPHLGWIIGFMFLVSFVGLFALVPMRKVMIVDYKLTYPSGTATAYLINGFHTPEGADLAKKQVRTLGKYFSISFLWAFFQWFYTAGDNCGFSSFPTFGLEAFKNRFYFDFSPTYVGVGMICPYIVNVSLLIGGIISWGIMWPLISKKKGSWYPETLPESSLLGLQAYKVFITIAVILGDGLYNFVKVFGYTIKGFIVMYKNKNSNTLPISDNGTPANATEEESFDDKRRNELFLKDQIPKTVAIGGYVVLAVITSGCLPLIIPQLKWYYILIAYIFAPIMAFCNAYGSGLTDWSLATTYGKLAIFVFGAWAGASHGGVLVGLAACGVMMNIVGTASDLMQDFKTGYMTLASPRSMFVSQVIGTAMGCVIAPCVFWLFYKSFNIGASDGAYPAPYTIMYRNMAILGVNGLSSLPKYCLTLCYIAFVAAFIINLIKDLVPERVAKYIPIPMAAAIPFYLGPYFAIDMFMGSVILYFWEWRNKDEAQSFGPAVASGLMCGDGLWALPQAVLSLVNVNPPLCMKFLSRAANAKVDTFLGN
What is the function of this protein?
May be involved in the transport of nicotianamine-chelated metals.
What are the official names of this protein?
Probable metal-nicotianamine transporter YSL11, Protein YELLOW STRIPE LIKE 11, OsYSL11.
What is the protein family that this protein belongs to?
Belongs to the YSL (TC 2.A.67.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PROB_PROM0
Sequence: MKTWVIKIGTSILRGTEETSTEEVIENLSRSFTSFLSKGNKLILVTSGAVGLGCQKLNIKTRPNDLSTLQATAAVGQVNLMSLYDKVFNKLGLNIAQILITKADFNSRESFNNASKTLKRLIDLNVIPIVNENDTVANEELKYGDNDTLSALVALAINANKLILLTDIENLYSKDPRNNKDAQPIKEVHNSELKEIKDKNIQNSNNEWGTGGISTKLISAEIATKGGVEVQLVDGTNKKNLIEIFNDNKIGTLFYPVEKPIGNKKSWLSHAIQTVGKITLDDGASFAIKKKGASLLAVGVKNVEGNFTINQAVKIVNTNDKEVAKGLVSISSDKLRSILNNKENNNSSIIVVHRDVLALS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_VITVI
Sequence: MFPMVTGFMNYGQQTVRAARYIGQSFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKQLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIDDYTIRTILNSPQITSE
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: DPO4_CORDI
Sequence: MQRWVIHVDMDAFFASCEQLTRPTLRGRPVLVGGASGRGVVAGASYEARTFGARSAMPMYQAKALIGMRGVVVSPRFAVYRAASQRVFSILERMGGTVEKISIDEGFVEPPELYGASASEVDTWAQRLRAVIRDETGLPASVGGGAGKQVAKICSDLAKPDGIYLCAASEHEEKMYPLPVGRLWGVGPVTRTKLQQLGVETIGDLARMSEREIDISLGTTVGRSLWRLAQGHDDREVAPRAIAKQISVEHTYPKDLVTSRAVDTAIIRASRESHRRLLDDGRGARTVSVKLRMADFRIESRSATLPYATDNLDTVTATALKLARYPDEVGPIRLVGVGLSGLEDARQDILFPELDRVVPVKDTDFEVGVSDPHDSDLEISTTDESPTAIGWRATQDIWHPDYGHGWVQGLGHGKITVRFETRTTGPGKVRTFDTNDALLSSADPINSLDWS
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CED2_CAEEL
Sequence: MTTNGFDPFEWRSFYFPGMSREEAHKLLGEPQVSIGTFLMRDSSRPGEYSLTVREADEGNAVCHYLIERGEPKEDGTAAAGVKIANQSFPDIPALLNHFKMRVLTEASLLAAYKKPIIEVVVGTFKFTGERETDLPFEQGERLEILSKTNQDWWEARNALGTTGLVPANYVQIQMEFHNDRTSKGASQSSIGSSGGGAERFSSASTSSDNIELQPRLPAKAKVTFDRVPNAYDPTQLRVKKGQTVLVTQKMSNGMYKAELDGQIGSVPHTYLRFTAVSE
What is the function of this protein?
Required for cell migration and engulfment of cell corpses but not for programmed cell death/apoptosis (PubMed:10707082, PubMed:6857247, PubMed:1936965, PubMed:11449278, PubMed:15744306, PubMed:19402756, PubMed:20226672).  Has a role in the migration of the 2 gonadal distal tip cells (DTCs) (PubMed:10707082).  Plays a role in protecting dopaminergic neurons from oxidative stress-induced degeneration (PubMed:29346382).
What are the official names of this protein?
Cell death abnormality protein 2, Cell-corpse engulfment protein CED-2.
What is the protein family that this protein belongs to?
Belongs to the CRK family.
Protein: PTR34_ARATH
Sequence: MQIEMEEKFEDWRGKEAISGKHGGIKAAFIACVVETMENMVFLACSTNFMMYFTKSMNYSTPKAATMVTNFVGTSFLLTIFGGFVADSFLTRFAAFVLFGSIELLGLIMLTLQAHITKLQPQGGKKPSTPQSTVLFTGLYAIAIGVGGVKGSLPAHGGDQIGTRNQRLISGFFNWYFFSVCLGGFLAVTLMVWIEENIGWSSSFTISTAVLASAIFVFVAGCPMYRFKRPAGSPLTRIVNVFVSAARNRNRFVTDAEVVTQNHNSTDKSIHHNKFKFLNKAKLNNKISATQVEETRTFLALLPIFGSTIIMNCCVAQMGTFSVQQGMVTNRKLSRSFEIPVASLNAIPLLCMLSSLALYELFGKRILSNSERSSSFNLKRIGYGLALTSISMAVAAIVEVKRKHEAVHNNIKISVFWLELQFVMLSLSDMLTVGGMLEFFFRESPASMRSMSTALGWCSTAMGFFLSSVLVEVVNGITGWLRDDLNESRLELFYLVLCVLNTLNLFNYIFWAKRY
What is the function of this protein?
Involved in (+) and (-)-abscisic acid transport (ABA) and in gibberellin import.
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 4.1, AtNPF4.1, Protein ABA-IMPORTING TRANSPORTER 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y4480_CAUSK
Sequence: MLMVISPAKSLDFTAPDQVLPLTTPELKPQIAELAKVTRKLTAADLRRLMHISEKLAALNHERFQHFDPQVEEGLQAVIAFNGDVYAGLNARELDRPALEWAQDHLRILSGLYGVLRPFDALQAYRLEMGARLKTKRGANLYDFWGETIAKTLNAAGKDHADPTLVNLASQEYFGAVDAKALKLPVVTCHFKEEKGNTLRVLGFFAKKARGRMARFAIDNRIDKAEGLKGFNLDGYEYRADLSTPADWVFARLQP
What are the official names of this protein?
UPF0246 protein Caul_4480.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: NCAM1_CHICK
Sequence: MLPAAALPWTLFFLGAAASLQVDIVPSQGEISVGESKFFLCQVAGEAKYKDISWFSPNGEKLTPNQQRISVVRNDDFSSTLTIYNANIDDAGIYKCVVSSVEEGDSEATVNVKIFQKLMFKNAPTPQEFKEGDDAVIVCDVVSSLPPTIIWKHKGRDVMLKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPSVRARQSTMNATANLSQSVTLACDADGFPEPTMTWTKDGEPIEQEDNEEKYSFNYDGSELIIKKVDKSDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENKTAMELEDQITLTCEASGDPIPSITWKTSTRNISNEEKTLDGRIVVRSHARVSSLTLKEIQYTDAGEYVCTASNTIGQDSQAMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSAVISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESSEFILVQADTPSSPSIDRVEPYSSTARVEFDEPEATGGVPILKYKAEWRALGEGEWHSRLYDAKEANVEGTITISGLKPETTYSVRLSAVNGKGVGEISLPSDFKTQPVREPSAPKLEGQMGEDGNSIKVNVIKQDDGGSPIRHYLIKYKAKHSSEWKPEIRLPSGIDHVMLKSLDWNAEYEVYVIAENQQGKSKPAHYAFRTSAQPTVIPASTSPTSGLGTAAIVGILIVIFVLLLVAVDVTCYFLNKCGLLMCIAVNLCGKSGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEHTADTAATVEDMLPSVTTGTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAIPDSNAMSPGQATPAKAGASPVSPPPPSSTPKVAPLVDLSDTPSSAPATNNLSSSVLSNQGAVLSPSTVANMAETSKAAAGNKSAAPTPANLTSPPAPSEPKQEVSSTKSPEKEAAQPSTVKSPTETAKNPSNPKSEAASGGTTNPSQNEDFKMDEGTFKTPDIDLAKDVFAALGTTTPASVASGQARELASSTADSSVPAAPAKTEKTPVEDKSEVQATEIRHLQQK
What is the function of this protein?
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
What are the official names of this protein?
Neural cell adhesion molecule 1, N-CAM-1, NCAM-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PGK_BRUSU
Sequence: MFRTLDDANVQSKRVLVRIDLNVPMANGEVTDLTRIERIVPTIAELSRKGAKVILLAHFGRPKGVASDENSLKHVVKPLSKVLDHSVHFAEDCIGDKAKAAVDALKDGDVLLLENTRFHKGEEKNDPEFVQALAANGDLYVNDAFSAAHRAHASTEGLAHVLPAFAGRAMQAELEALEKGLGNPARPVVAIVGGAKVSTKLDLLSNLIEKVDALVIGGGMANTFLAAKGLDVGKSLCEHELASTAREIMAKAETTKCAIILPVDAVVGWHFAADTPHQTYGVDSVPGDAMILDAGELSTDLIASAIDDAATLVWNGPLGAFELRPFDTATVKVARHVAKRTKEGKLVSVGGGGDTVAALNHAGVVDDFTYISTAGGAFLEWMEGKPLPSVDVLKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAIA_THEAC
Sequence: MSIEIRKLSIEDLETLIEVARESWKWTYAGIYSEEYIESWIREKYSKEKLLNEIVRSQSNLDILFLGAFADSTLIGFIELKIIANKAELLRLYLKPEYTHKKIGKTLLLEAEKIMKKKGILECRLYVHRQNSVGFSFYYKNGFKVEDTDGSDFIMEKKYES
What is the function of this protein?
Involved in the protection against polyamine toxicity by regulating their concentration.  Could also be involved in the negative control of sporulation as well as production of degradative enzymes such as alpha-amylase, levansucrase and alkaline phosphatase.  Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and release both CoA and the acetylated product.  It can use a variety of substrates including spermidine, L-tryptophan, L-leucine, L-lysine, dopamine and tyramine.
What are the official names of this protein?
Spermidine N(1)-acetyltransferase, SAT, GCN5-related N-acetyltransferase, GNAT, Protease synthase and sporulation negative regulatory protein PAI 1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: SYE_LACP3
Sequence: MADRPIRVRYAPSPTGHLHIGNARTALFNYLFARHNNGTLVLRIEDTDTKRNVADGEKSQMENLHWLGIDWDEGPDKGGDFGPYRQSERKDIYDKLIKQLVDKGFAYESYRTEEELKADREAQKARHEMPHYEYEYEGMTDAEKADAIAAAKAKGLEPVIRFHIPMDKTYEWDDIVKGKISIDANTLGGDFVIQKRDGMPTYNFAVVVDDHMMQISHVLRGDDHIANTPKQLAIYDAFGWEPPIFGHMTLIINGATGKKLSKRDETVLQFIEQYRELGYLPDAMFNFITLLGWSPVGEDEIFTKKEFIKQFDPKRLSKSPARFDQKKLEWVNNQYIKAKQKTNPNELMSLSLANLIEDGKIHSDPDPKTIEWARQLISLYTDQMSYTAQISKLADIFFDKATDLTDDERKELADDNAKPVIEAFAKKIRALDTFDAYSIGGIVNEVKQETKVKGRKLYMPIRIAATLRMHGPQLAETIELMGRDQVLKNVDLVTGQL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMLN1_CUPSE
Sequence: AQIDCDKECNRRCSKASAHDRCLKYCGICCEKCHCVPPGTAGNEDVCPCYANLKNSKGGHKCP
What are the official names of this protein?
Cypmaclein.
What is the protein family that this protein belongs to?
Belongs to the GASA family.
Protein: AEBP2_BOVIN
Sequence: MAAALTDMADLEELSRLSPLPPGSPGPAARGRAEPPEEEEEEDEEEEAEAEAVAALLLNGGGGGGGVGGGEAETMSEPSPESASQAGEDDDEEEDDDEEEEDESSSGGGEEESSAESLVGSSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKNIAYNCCWDQCQACFTSSPDLADHIRSIHVDGQRGGVFVCLWKGCKVYNTPSTSQSWLQRHMLTHSGDKPFKCVVGGCNASFASQGGLARHVPTHFSQQNSSKVSSQPKAKEESPSKAGMNKRRKLKNKRRRSLPRPHDFFDAQTLDAIRHRAICFNLSAHIESLGKGHSVVFHSTVIAKRKEDSGKIKLLLHWMPEDILPDVWVNESERHQLKTKVVHLSKLPKDTALLLDPNIYRTMPQKRLKRTLIRKVFNLYLSKQ
What is the function of this protein?
Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene.  Plays a role in nucleosome localization of the PRC2 complex.
What are the official names of this protein?
Zinc finger protein AEBP2, Adipocyte enhancer-binding protein 2, AE-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the AEBP2/jing C2H2-type zinc-finger family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to chromatin as part of the PRC2 complex.
Protein: DDL_NEIG1
Sequence: MQNFGKVAVLMGGFSSEREISLDSGTAILNALKSKGIDAYAFDPKETPLSELKERGFQTAFNILHGTYGEDGAVQGALELLGIPYTGSGVAASAIGMDKYRCKLIWQALGLPVPEFAVLYDDTDFDAVEEKLGLPMFVKPAAEGSSVGVVKVKEKGRLKSVYEELKHLQGEIIAERFIGGGEYSCPVLNGKGLPGIHIIPATEFYDYEAKYNRDDTIYQCPSEDLTEAEESLMRELAVRGAQAIGAEGCVRVDFLKDTDGKLYLLEINTLPGMTGHSLVPKSAAVTGVGFADLCIEILKAAHVG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_ALBFT
Sequence: MLLIPAIDLKDGHCVRLKQGDMDQSTTFSEEPFVMARNWVDKGARRLHLVDLNGAFAGHPKNELAIRKILKDVGSEVDVQLGGGIRDLDTIERYLDAGLRYVIIGTAAVKNPGFLQDACTAFGGHIIVGLDARDGKIATDGWSKLTRHDVVDLAKKFEDYGVESIIYTDISRDGMLSGINIEATVRLAQALTIPVIASGGLSGMADIEALCAVENEGIEGVICGRAIYSGDLDFEAAQERANELNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR4N2_HUMAN
Sequence: MESENRTVIREFILLGLTQSQDIQLLVFVLVLIFYFIILPGNFLIIFTIKSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSAKKIISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHYPTVMNPRTCYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRIRGSSSEAKNKAMSTCITHIIVIFFMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKASMKKVFNKHIA
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4N2, Olfactory receptor OR14-13, Olfactory receptor OR14-8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYGL_MOUSE
Sequence: MAKPLTDQEKRRQISIRGIVGVENVAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQTGTKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGMGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWAKAWEITKKTFAYTNHTVLPEALERWPVELVEKLLPRHLEIIYEINQKHLDRIVALFPKDISRMRRMSLIEEEGGKRINMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLADLIAEKIGEDYVKDLSQLTKLHSFVSDDIFLREIAKVKQENKLKFSQFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIKKDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLITSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPNQPDLFKDIINMLFYHDRFKVFADYEAYVKCQEKVSQLYMNQKAWNTMVLKNIAASGKFSSDRTIKEYAKDIWNMEPSDLKISLSNESSNGVSANGK
What is the function of this protein?
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
What are the official names of this protein?
Glycogen phosphorylase, liver form.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.