PharMolix/UniProtQA huggingface dataset:
Protein: GLYC_TACV5
Sequence: MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTQFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSADVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGEQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNVPPGGYCLEKWMLVASELKCFGNTAIAKCNQNHDSEFCDMLRLFDYNKNAIKTLNEETKTRVNVLSHTINALISDNLLMKNKIRELMSVPYCNYTRFWYVNHTLSGQHSLPRCWMIRNNSYLNSSEFRNEWILESDFLISEMLSKEYSERQGRTPITLVDICFWSTVFFTSTLFLHLIGFPTHEHIRGEGCPLPHRLNSMGGCRCGKYLPLKKPTIWHRRH
What is the function of this protein?
Interacts with the host receptor.
What are the official names of this protein?
Pre-glycoprotein polyprotein GP complex, Pre-GP-C.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae GPC protein family.
What are the subcellular locations of this protein?
[Glycoprotein G1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Host Golgi apparatus membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Glycoprotein G2]: Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host Golgi apparatus membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Binding to the stable signal peptide masks endogenous ER localization signals in the cytoplasmic domain of G2 to ensure that only the fully assembled, tripartite GP complex is transported for virion assembly. SUBCELLULAR LOCATION: [Stable signal peptide]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein.
Protein: PFPB2_ARATH
Sequence: MASQLDLIGGDYIAGISINPPTNSRVTSVYSEVQASRIDHTLPLPSVFKTPFKIIDGPPSSSAGHPEEIEKLFPNLFGQPSALLVPNQSNEVSSDQKLKIGVVLSGGQAPGGHNVICGIFDYLQEYARGSSLFGFRGGPAGIMKGKYIELTSEFVYPYRNQGGFDMICSGRDKIETPEQFKQAEETVTKMDLDGLVVIGGDDSNTNACLLAEHFRAKNMKTLVIGCPKTIDGDLKSKEVPTSFGFDTACKIYSEMIGNVMIDARSTGKYYHFVRLMGRAASHITLECALQTHPNITIIGEEVFEKKLTLKNVTDNIVDVIYKRAENGYNYGVILVPEGLIDFIPEVQQLISELNEVLAEGNVDEEGQWKKNLKKETLEIFEFLPQTIQEQLMLERDPHGNVQVAKIETEKMLIQMVETELEKKKTEGTYEREFMGKSHFFGYEGRCGLPTNFDATYCYALGYGAGSLLQSGKTGLISSVGNLAAPVEEWTVGGTALTSLMDVERRHGKFKPVIKKAMVELEGAPFKKFASQREEWALKNRYISPGPIQFKGPGSDARNHTLMLELGAQA
What is the function of this protein?
Catalytic subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase.  Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis.  Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta 2, PFP 2, 6-phosphofructokinase, pyrophosphate dependent 2, PPi-PFK 2, Protein MATERNAL EFFECT EMBRYO ARREST 51, Pyrophosphate-dependent 6-phosphofructose-1-kinase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_PARDP
Sequence: MRLSRYFMPVLKEDPKEAQIVSHRLMLRAGMIKQQAAGIYSWLPLGYKVLRRIEQIVHEEQARAGHIAMLMPTLQSADLWRESGRYDDYGEEMLRIKDRHKRDLLYGPTNEEMITDIFRSHVNSYKDLPLTLYHVQWKFRDEIRPRFGVMRGREFLMKDGYNFDLTKEDALHAYNRHLVSYLRTYERMGLQAIPMRADGGPIGGDYTHEFLVLAETGESEVFYDSEITDLKFGDRRIDYDDVAQCRAVLEEFTSRYARTDETHDAALFEQIPKERRRVARGIEVGQIFYFGTKYSEPMGATVVGPDGSRVPVHMGSHGIGVSRLLGAIIEASHDDRGIIWPEGVTPFHVGIVNLKQGDASTDGACEALYAELKAQGLDALYDDRDERAGAKFATMDLVGLPWRITVGPRGLAANKVELTSRRTGESVEMSPQEAVVRLREIYQPVFDAAK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZBTB4_HUMAN
Sequence: MPPPAEVTDPSHAPAVLRQLNEQRLRGLFCDVTLIAGDTKFPAHRSVLAASSPFFREALLTSAPLPLPPATGGAAPNPATTTAASSSSSSSSSSSSSSSSASSSSSSSSSSPPPASPPASSPPRVLELPGVPAAAFSDVLNFIYSARLALPGGGGDGAAVAEIGALGRRLGISRLQGLGEGGDAWVPPTPAPMATSQPEEDSFGPGPRPAGEWEGDRAEAQAPDLQCSLPRRPLPCPQCGKSFIHPKRLQTHEAQCRRGASTRGSTGLGAGGAGPGGPAGVDASALPPPVGFRGGPEHVVKVVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWETFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPKLNTLKLYRLLPMRAAKRPYKTYSQGAPEAPLSPTLNTPAPVAMPASPPPGPPPAPEPGPPPSVITFAHPAPSVIVHGGSSSGGGGSGTASTGGSQAASVITYTAPPRPPKKREYPPPPPEPAATPTSPATAVSPATAAGPAMATTTEEAKGRNPRAGRTLTYTAKPVGGIGGGGGPPTGAGRGPSQLQAPPPLCQITVRIGEEAIVKRRISETDLRPGELSGEEMEESEEDEEEEDEEEEEEDEEESKAGGEDQLWRPYYSYKPKRKAGAAGGASVGGSGLPRGRRPPRWRQKLERRSWEETPAAESPAGRARTERRHRCGDCAQTFTTLRKLRKHQEAHGGGSHSSRAGRRPSTRFTCPHCAKVCKTAAALSRHGQRHAAERPGGTPTPVIAYSKGSAGTRPGDVKEEAPQEMQVSSSSGEAGGGSTAAEEASETASLQDPIISGGEEPPVVASGGSYVYPPVQEFPLALIGGGREPGGGRGKSGSEGPVGAGEGDRMEGIGAAKVTFYPEPYPLVYGPQLLAAYPYNFSNLAALPVALNMVLPDEKGAGALPFLPGVFGYAVNPQAAPPAPPTPPPPTLPPPIPPKGEGERAGVERTQKGDVG
What is the function of this protein?
Transcriptional repressor with bimodal DNA-binding specificity.  Represses transcription in a methyl-CpG-dependent manner.  Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS).  Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688).  Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 4, KAISO-like zinc finger protein 1, KAISO-L1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to chromocenters.
Protein: SEPF_PROMP
Sequence: MSLISRLKAVVAGDDFLDDDFDELDYASEDEFNGNDDLKQNYKKSNALSNSNPFEFMNNNRTSNVVGMPGIANSSSEVNLMEPRSFDEMPQAIQALRERKTVILNLTMMDPDQAQRAVDFVAGGTYAIDGHQERVGESIFLFAPSCVNVTSSFPEEASPSNVSSKKTSQYKFETNTTPEPAWGESKLSAYN
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RL14_LYSSC
Sequence: MILQESRMKVADNSGAREVLTIKVLGGSGRKTANIGDIVVCTVKKATPGGVVKKGDVVKAVIVRTKSGVRRKDGTYIKFDENACVIIRDDKSPRGTRIFGPVARELRDSNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NUOI_FLAPJ
Sequence: MSTTIQNISLSGRKKQVSNKEMTFLESLYLVAIVKGLLITIKHFFRKKVTIHYPEQVREMSPVYRGQHMLKRDEQGRENCTACGLCALSCPAEAITMKAAERKSNEKHLYREEKYAEIYEINMLRCIFCGLCEEACPKDAIYLTTSKVLVPSNYERENFIFGKDKLVMPLDIAMQNAQLKNAN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DLTC_STRPF
Sequence: MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVELESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKVI_BACSU
Sequence: MEQSKGSASQLAFVYVGTVVGAGFATGREIVEFFLKFGWFGFFGILVSGGMFTLLGAKLMIISKRINAKSYQEMNIFLFGATAGRIINVFMLFVLLGVTSVMLSGAGALFEEQLGMSAQIGMLITIGLSLIVMTRGVKGIFGVNVFVVPLLIIFSMIVVADSFIFSESRNAAQWVWPHRWDWLLSAVSYGALNLSLAQAVLVPLANEMSSEKVIKKGALIGGTMLTIVLSASFLSLSTLPDVFLYDIPMAQVVYLFARSVHLIYLLIIFGEVFTSVIGNLYGLEKQVQSFLPVKSKYIFAAIMITAYITSQIGYGRLISTIYPLFGYVSLAFIGALLCKKAPRRRSL
What are the official names of this protein?
Uncharacterized membrane protein YkvI.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDKB_MERAA
Sequence: MEQTFVAIKPDGVQRGLCGEVMKFIQPMKHYLDLKDMPFYAGLCKYMSSGPVFAMVWEGEGIVKMMLGETNPADSKPGSIRGDFCINIGRNIIHGSDTVENAKMEVGLWFKPEEFVAYAEKAKAWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.
What are the official names of this protein?
Nucleoside diphosphate kinase B, NDK B, NDP kinase B.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, lamellipodium. Cell projection, ruffle.
Protein: PRIO_LOPAT
Sequence: MLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWHKPSKPKTSMKHMAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYEKESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: KCNK6_HUMAN
Sequence: MRRGALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNADEDDRVDILGPQPESHQQLSASSHTDYASIPR
What is the function of this protein?
Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions.
What are the official names of this protein?
Potassium channel subfamily K member 6, Inward rectifying potassium channel protein TWIK-2, TWIK-originated similarity sequence.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NKAI1_HUMAN
Sequence: MGKCSGRCTLVAFCCLQLVAALERQIFDFLGYQWAPILANFLHIMAVILGIFGTVQYRSRYLILYAAWLVLWVGWNAFIICFYLEVGQLSQDRDFIMTFNTSLHRSWWMENGPGCLVTPVLNSRLALEDHHVISVTGCLLDYPYIEALSSALQIFLALFGFVFACYVSKVFLEEEDSFDFIGGFDSYGYQAPQKTSHLQLQPLYTSG
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1, Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1, Protein FAM77C.
What is the protein family that this protein belongs to?
Belongs to the NKAIN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YMS4_MAIZE
Sequence: YVLIMRLKLKRKIYRADFSEYKGLWSLYNRATDNLYSHLQRALEKYENFGVSAKHKVLQCLVHVVTSQSDNSVRYVYGNIFALVRLGTYVTVWYCYTESAPDFISVDPHYLDIELIIDLFKVRKLFVWIPYEEVISTSILEAYDAVVERTALTDCLDRKLREEELSDKFEFWGKCSDGDHTIDSVEENATIEYASSKEGSACKEGVDSSCKEEGGGCEEEGSGSEEDSDDSDNPRYLAFGVVVLVGVLLYVWYCSR
What are the official names of this protein?
Uncharacterized 29 kDa protein in mitochondrial S-1 DNA, URF 4.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SURE_HAEI8
Sequence: MRILVSNDDGFHAEGIQVLAMELRKIAEVIIVAPDRNRSAASSSLTLVEPLRPRHLDNGDYCVNGTPADCVHLALNGFLSGQVDLVVSGINAGCNMGDDTIYSGTLAAALEGRHLGLPAIAVSLDGRQHYETAARVVCDLIPKLHHQLLNPREIININVPDLLFEELKGYKVCRLGYRASSAEVIKQKDPRDETIYWIGPSALPEDESEGTDFYAVKNGYVSITPIQADLTAYHSLLSLQNWLEQEFTK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOA1_LEPWE
Sequence: MKAVVLTLAVLFLTGSQARHFWQQDEPQSPWDRVKDLATVYVDVVKDGGRDYVAQFESSALGKQLNLKLLDNWDSLSSTVAKLREQIGPVTQEFWDNLEKETEVLRQEMNKDLEEVKKKVQPYLDEFQSKWHEEVELYRQKVAPLGAELREGARQKLQELQEKLSPLGEELRDRARTHVDALRAQLAPYGEQLRERLAARLQALKEGGGAALTEYRAKASEHLSALREKAKPALEDLRQGLLPVLENFRVSLLAAVDEATKKLNSQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSRP_ALCBS
Sequence: MKRTAFYLSDGTGITAETLGHSMLSQFGSIEFIQVTLPFVQSDEQTREAVARINKAAKEDGAKPVVFSTLVNTDHRAILHGCDALILDLFGAFLRPLEDELGVRSSHKINQSHAIRDAESYRIRINAVHFALDNDDGARTRHYDQADIILIGVSRSGKTPTCLYLALQFGLFTANYPLTEDDFDDLRLPKALMEHKHKLFGLTIDADRLSAIRSERKAGSKYASPRQCDMELRALEAMYNKHNIPYLDATELSIEEISTRVLAMKGLKRRLQ
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: DEOB_SERP5
Sequence: MKRTFIMVLDSFGIGASEDAAKFGDQGSDTLGHIAEVCARGEANVGRQGPLTLPNLSRLGLGKAAEESTGTFPQGLDRNADIIGAYAHASELSSGKDTPSGHWEIAGVPVLFDWGYFSDEHNSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVFQIACHEETFGLDRLYELCEIAREELTEGGYNIGRVIARPFLGDKPGNFQRTGNRHDLAVEPPAPTVLKKLVDEKGGEVVSIGKIADIYANVGITKKVKATGIDALFDATLIEMEKAGDNTIVFTNFVDFDSSYGHRRDVAGYAAALELFDRRLPELLKLVKDEDIIIFTADHGCDPTWPGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTVASYFGVSPMDYGKSMF
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHS7_SORBI
Sequence: MAGATVTVEEVRKAQRATGPATVLAIGTATPANCVHQADYPDYYFRITKSEHMTDLKEKFKRMCDKSQIRKRYMHLTEEYLAENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSMVGQALFGDGAAAVIVGADPDKRVECPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERSLEEAFKPLGITDYNSIFWVAHPGGPAILDQVEAKVGLKKERMRATRHVLSEYGNMSSACVLFILDEMRKRSAEEGQATTGEGFDWGVLFGFGPGLTVETVVLHSVPITIAAITA
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 7, Naringenin-chalcone synthase 7.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: HBA_PANTR
Sequence: MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL21_PSEAE
Sequence: MYAVIVTGGKQHKVTEGEFLKVEKLDVATGEAIDFDRVLLVANGEDVKIGLPVVEGAKVTAEVVSHGRHDKVRIIKFRRRKHHMKRQGHRQWFTEIKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: NCAP_I77AF
Sequence: MASQGTKRSYEQMETGGDRQNANEIRASVGRMVGGIGRFYIQMCTELKLSDNEGRLIQNSITIERMVLSAFDERRNKYLEEHPSTGRDPKKTGGPIYRRRDGKWVRELVLYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGVNDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGAVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVLPRGQLSTRGVQIASNENMETMNSSTLELRSKYWAIRTRSGGNTNQQRASAGQVSVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMENSRPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEFDS
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LEU1_RALSO
Sequence: MSDKLIIFDTTLRDGEQSPGASMTKEEKIRIAKQLERLKVDVIEAGFAASSNGDFEAIRAIAQSVKDSRICSLARANDRDISRAAEALKPAGQFRIHTFIATSALHMEKKLRMTPDQVYEQARLAVRFARQFTDDIEFSPEDGSRSDMDFLCRVLEGVIAEGATTINLPDTVGYAVPEGYAALIRSVRERIPNSDKAIWSVHCHNDLGMAVANSLAAVKLGGARQIECTINGLGERAGNTSLEEVVMAVKTRRDYFNLDVGVDTTQIVPASKLVSQITGFVVQPNKAVVGANAFAHASGIHQDGVLKARDTYEIMRAEDVGWTANKIVLGKLSGRNAFKQRLQELGIELDSEAELNAAFTRFKELADQKAEIFDEDIVAIVSNEAQHAEGEHFRFVSLSQRSETGERPHARIVFVADGKEVTGEAEGNGPVDATLNAIESKVASGAEQLLYSVNAITTGTQAQGEVTVRLSKSGRIVNGVGTDPDIVAASAKAYLAALNKLQDKSSEKLNPQI
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RIFK_YEAST
Sequence: MFTWTIYVSLLLVLAGTFLMNRNTNTDIIDTFKREVDLPIPAQPGPPFPLVTDYCDIVCGFGRGSAELGIPTANVPINQLPKGINDLDLGVYFGFAHIKTVDGQELSVETRRDGRTVVYNYGQYLSEANDDLSVLPMVLSVGKNPFYGNDFKTMELHIIHDFKNDFYGARVKFNILGHIRPELNYTTKEALIEDINIDIRTAQTVLATPPYQVFKQQL
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
What are the official names of this protein?
Riboflavin kinase, Flavin mononucleotide kinase 1.
What is the protein family that this protein belongs to?
Belongs to the flavokinase family.
What are the subcellular locations of this protein?
Microsome. Mitochondrion inner membrane. Endoplasmic reticulum. Note=90% microsomal. 10% mitochondrial. Found to be present in the inner membrane of mitochondria. The C-terminus is located in the matrix.
Protein: RCO1_YEAST
Sequence: MDTSKKDTTRSPSHSNSSSPSSSSLSSSSSKEKKRPKRLSSQNVNYDLKRRKIITSEGIERSFKNEHSNLAVEDNIPEEEPKELLEKDSKGNIIKLNEPSTISEDSKVSVTGLPLNKGPSEKIKRESLWNYRKNLGGQSNNSEMTLVPSKRFTQVPKNFQDLNRNDLKTFLTENMTEESNIRSTIGWNGDIINRTRDREPESDRDNKKLSNIRTKIILSTNATYDSKSKLFGQNSIKSTSNASEKIFRDKNNSTIDFENEDFCSACNQSGSFLCCDTCPKSFHFLCLDPPIDPNNLPKGDWHCNECKFKIFINNSMATLKKIESNFIKQNNNVKIFAKLLFNIDSHNPKQFQLPNYIKETFPAVKTGSRGQYSDENDKIPLTDRQLFNTSYGQSITKLDSYNPDTHIDSNSGKFLICYKCNQTRLGSWSHPENSRLIMTCDYCQTPWHLDCVPRASFKNLGSKWKCPLHSPTKVYKKIHHCQEDNSVNYKVWKKQRLINKKNQLYYEPLQKIGYQNNGNIQIIPTTSHTDYDFNQDFKITQIDENSIKYDFFDKIYKSKMVQKRKLFQFQESLIDKLVSNGSQNGNSEDNMVKDIASLIYFQVSNNDKSSNNKSASKSNNLRKLWDLKELTNVVVPNELDSIQFNDFSSDEIKHLLYLKKIIESKPKEELLKFLNIENPENQSE
What is the function of this protein?
Catalytic component of the RPD3C(S) histone deacetylase complex responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, DNA damage response, osmotic stress response and developmental events.
What are the official names of this protein?
Transcriptional regulatory protein RCO1.
What are the subcellular locations of this protein?
Nucleus.