PharMolix/UniProtQA huggingface dataset:
Protein: KCNJ9_MOUSE
Sequence: MAQENAAFSPGSEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGAGDGADKEHNGCLPPPESESKV
What is the function of this protein?
This receptor is controlled by G proteins.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.
What are the official names of this protein?
G protein-activated inward rectifier potassium channel 3, GIRK-3, Inward rectifier K(+) channel Kir3.3, Potassium channel, inwardly rectifying subfamily J member 9.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ9 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUVC_RHOBA
Sequence: MGTQVVTARPGSASCILGIDPGLNTTGYAVISREGPRLCLREAGVIKSRRSDTLPERLREIHVGLSEVFAVHAVDLMALEQLFSHYDRPRTAILMGHARGVICLAAASAGVPVEHYEPTRVKKVMTGNGRAPKSQIQLAVKMQLNLQSVPEPADVADAMAISLCGHYLANNPIDQALA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: LIPA_PORG3
Sequence: MAQHVKKPEWLKIRLGGNEKFTETKSIVEGHCLHTICTSGKCPNMGECWSRGTATFMIGGDICTRACRFCNTLTGRPKPLNEAEPTHVALSIKLMGLNHAVVTSVDRDDLPDYGATHWVKTIQEIRRINSGVTLEVLIPDFKGRMDLVDMIIEASPDVISHNLETVRRLTPSVRSVATYDTSLAVLRHIAQSGKMPAKTGMMLGLGETEEEILELMDDALAAGVSVITIGQYLQPSRKNLPVVEYITPEQFEHLRLVGIEKGFRTIESAPLVRSSYHAERHL
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_RHORT
Sequence: MAELLLELLSEEIPARMQVRAIEDLTKLVGTGLAEAGLSHGGLRGFVTPRRLTLVVDGLPVAQPDVHEERRGPKADAPDKAIAGFLGSLGLTRDQLETRETPKGPFLFAVIERKGRPTAEVLPEIIYRALTALSWPKSMRWARGQFTWVRPLHSILAVFEGAPLRGAIGLGVSLEGLPVGFIADPAAAPEGTPLLAFGATTRGHRFLAPEPFPVRDFADYAARLRQAHVLIDREERKRVIAERAAALAAGEGLRVKDDPALLEEITGLVEWPVPLMGHIDKAFMDVPAEVLTTSMRSHQKYFSVENADGTLNARFVVVSNMDATDSSARVVAGNERVLRARLSDAKFFWDQDRKAPLAGKVEALGARVFHAKLGSDLDKVTRVRAGAAWLAARVPGADASLVDRAALLAKADLTTGMVGEFPELQGLMGRYYALHDGEPPAVAQAIRDHYSPVGPGDACPTAATSVCVALADKIDTLAGFWLIDEKPTGSKDPFALRRAALGVIRLIVENSLRLPLREVLGSAISTYGDRMLAQCGKADGTSSDVIEHDLIAFIAERLKVQQREKGVRHDLIEAVFSQGGEDDLVRLLARVSALADFLASEEGTNLLSAYRRATNIVRIEEKKDGKPVSGDPDNALFEQDEERALSLALDTLLGEVSPSLAAEDHAAAMRALARLRGPVDAFFDRVTVNADTPALRNNRLRLLARIGTAMATLADFSKIEG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_RICRS
Sequence: MTCKIIGCGGYLPSKIVSNDELAKFVDTNDEWIRTRTGITQRHIAGDTEYTSHLALKSAEKAIADAGISVNDIDLIITCTTTPDNSFPSVASKLQGYLGLTNIPSFDLQAVCAGFVYGLQVANSLISSDKYKTILLIGAEKMTSLLDWNDRTTCVLFGDGAGSVILQRSSDDSGLIDSNIFSSGADYDEILYTNGGVSMNGISGKIVMQGQKLFRHAIEKMQQSIKDLLHANQFSVSDIDYFIPHQANIRIINKLAELLNIEEHKVVKTVDKHANCSAASIPLALSTLKASGKIKKGDILLFSAIGAGLTWGSAFIRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M3R_DICDI
Sequence: MESLKNNGEKIENFLNQLKNLQSNVDKDFKEFSNSPNTLNAEKDGEFLDKHDEELYNKQIIRSRLEDKISNLSSSMINDIGNDFQTGFQTILYNLPGVGPVFQMIFNIMGNGINLEKFYQEIITQVEQMIKKSLEDYYKNQCNTIFKNLGKACDQHKDLTQKWYDKNGIKSMNHLGKEIPQSTSSTIESDDTLTPMIHASYLDLKIKFNDAITSFTDAKYRGHVAPLLTYTSVMYVAFLRDILKYGKEMKFDDSVLNGSANTPGIKKMLNDFVNVTLSEFLISGREYTNVVNSLQEGYWITYPPPIYKVWVPPQQASWVSPPASELAHKFFLAHSDNYPQGGDLIYIKKDGVYELSPNKITHALEVYYSSGGGYGVNDYPSFRYGGKPIIPLLAPVGNAVFTMLNPNRYKRTFKIRIVHVIVREAKWNLDCYDNQVGEAGSFNQNFVFTSTNIVSDPICGNIGTVGITEIPGPFTTDKKYIRLTCIRKVNFPASKNEGYAVGSRILSVQLIDL
What are the official names of this protein?
cAMP-regulated M3R protein, Proteasomal alpha-subunit 7-1.
What is the protein family that this protein belongs to?
To D.discoideum protein M3L.
Protein: SP2SA_BACSU
Sequence: MVLFFQIMVWCIVAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPTSLFTHWERYLIVAVSFALIDAFIFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASLCHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQNYVIKLTSDSIVTEFDYLLFTSLTSIYDLVLPIEEEGEG
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its toxic activity is neutralized by cognate antitoxin SpoIISB.  Expression in the absence of SpoIISB permits sporulation to stage II, when plasmolysis zones and holes in the peptidoglycan layer are observed, resulting in cell death.  Lethal when synthesized during vegetative growth in the absence of SpoIISB.  In E. coli both the membrane bound and soluble domain are required in cis for toxin activity.
What are the official names of this protein?
Stage II sporulation protein SA, Killer protein SpoIISA, Toxin SpoIISA.
What is the protein family that this protein belongs to?
Belongs to the SpoIISA toxin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FTHS_LIGS1
Sequence: MKDIEIAQKSEMLPITEVAQKVGLTADEIEQYGKYKAKISLPLSAREQTKRKLVLVTAINPTPAGEGKSTVTVGLGDAFSLLNKKVMIALREPSLGPVMGMKGGATGGGYSQVVPMEDINLHFTGDMHALTTANNTLAALIDNHIYQGNKLNIDQRRVIWKRVLDINDRALRHVVIGLGGATQGIPREDGFDITVASELMAILCLSKDISDLKKRIGQIVIGYNFDKEPVTVDQLGVTGAITLLLKDACKPNLVQTLAHTPAIVHGGPFANIAHGCNSVLATQTALNLADYTITEAGFGADLGAEKFLDIKTPVLGKTPDTIVIVATARALKMNGGVAKDNLDEENVAAVEQGFANLKKHIQSMKRYNVPVVVAINKFTQDTDAELAKIVELCEQDDTKAIVADVWAKGGEGATELAKAVIESCDNDQEFTRLYNSDDSVEEKINKIVTEIYGGDGVEFSAKAKRQLRQFEKLGWNHLPVCMAKTQYSLSDNAKVLGAPKGFKIHVREFVPKLGAQFLVALTGNILTMPGLPKVPAADGMDVDENGKISGLY
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: CAF20_ASHGO
Sequence: MAKYTEEELLQLKPTYDVAVNFDVDAFKAMIAEVAEHHEIADLFHQKARRRSSHHHGVKPKIKAHKPRITTDDDGWCTSTRKTSVVAVGDDGEPSPAFVAQETLRVKPNNKNIASSRPADTRDIVADKPTMSFNAFAALESDDEDQF
What is the function of this protein?
Acts as an inhibitor of cap-dependent translation.  Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA (By similarity).
What are the official names of this protein?
Cap-associated protein CAF20.
What is the protein family that this protein belongs to?
Belongs to the CAF20 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTG2_PONAB
Sequence: MTPARHFSARLRTVFEGVGHWALSTQAGLKPSRLLPQQASPRLLSVSCADLAKRQELPGKKPLSEKKLKRYFVDYRRVLVCGGNGGAGASCFHSEPRKEFGGPDGGDGGNGGHVILRADQQVKSLSSVLSRYQGFSGEDGGSKNCFGRSGAVLYIRVPMGTLVKEGGRVVADLSRVGDEYIAALGGAGGKGNRFFLANNNRAPVTCTPGQPGQQRVLHLELKTVAHAGMVGFPNAGKSSLLRAISNARPAVASYPFTTLKPHVGIVHYEGHLQIAVADIPGIIRGAHQNRGLGSAFLRHIERCRFLLFVVDLSQPEPWTQVDDLKYELEMYEKGLSERPHAIIANKIDLPEAQANLSQLRDHLGQEVIVLSALTGENLEQLLLHLKVLYDAYTEAELGQGRQPLRW
What is the function of this protein?
Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity.  Displays GTPase activity.  Involved in the ribosome maturation process (By similarity).
What are the official names of this protein?
Mitochondrial ribosome-associated GTPase 2, GTP-binding protein 5.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: BSHC_STAAR
Sequence: MDCKVVSLNEKDQFIPKIKSSDPVITGLFQYDAAQQISFEKRMSKENNGREAALANVIREYMNDLKLSSEQELNIQHLANGSKVVIGGQQAGLFGGPLYTFHKIFSIITLSKELTDTHKQQVVPVFWIAGEDHDFDEVNHTFVYNENHGSLHKVKYHTMEMPETTVSRYYPDKAELKQTLKTMFIHMKETVHTQGLLEICDRIIDQYDSWTDMFKALLHETFKAYGVLFIDAQFEPLRKMEAPMFKKILKKHQLLDDAFRATQKRTQNQGLKAMIQTDTNVHLFLHDENMRQLVSYDGKHFRLNKTDKKYIKEEIINIAENQPELFSNNVVTRPLMEEWLFNTVAFIGGPSEIKYWAELKDVFELFDVEMPIVMPRLRITYLNDRIEKLLSKYNIPLEKVLVDGVEGERSKFIREQASDQFIEKVEGMIEQQRRLYQDLLDEVAGNQNNINLVNKNNEIHIQQYDYLLKRYLLNIERENDISMKQFREIQETLHPMGGLQERIWNPLQILNDFGTDVFKPSTYPPLSYTFDHIIIKP
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: RR12_SACOF
Sequence: MPTVKQLIRNARQPIRNARKSAALKGCPQRRGTCARVYTINPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYRIIRGTLDAVAVKNRQQGRSKYGAKKPKK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PPIB_BACSU
Sequence: MKTGYFLLEDGNKIEFELYPEAAPGTVANFEKLANEGFYDGLTFHRVIPGFVSQGGCPHGTGTGGPGYTIKCETEGNPHTHEAGALSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGKVTSGLEFAKNMSNGDVMKEVRVEG
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B, PPIase B, Rotamase B.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHA2_RHOAC
Sequence: MNQGKIWTVVNPAVGLPLLLGSVAITALLVHLAVLTHTTWFPAFTQGGLKKAA
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-800/820 alpha chain, Antenna pigment protein alpha chain.
What is the protein family that this protein belongs to?
Belongs to the antenna complex alpha subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: MP31_MOUSE
Sequence: MWRDSLCTAAGYALGRRDAAALSSLLSEAAAMMEV
What is the function of this protein?
Inhibits lactate dehydrogenase (LDH)-mediated conversion of lactate to pyruvate in mitochondria by competing with mitochondrial LDH for binding to NAD(+).  Also inhibits cellular lactate utilization.
What are the official names of this protein?
PTEN upstream open reading frame MP31, Micropeptide 31.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DXS_SHEB2
Sequence: MSLDISQFPVLAQANTPNELRQLPQALLPQVADELREFLLKSVGISSGHFASGLGTVELTVALHYVYNTPFDRLIWDVGHQAYPHKILTGRRDKMHTIRQKDGLHPFPWREESEYDTFSVGHSGTSISAALAMAIAAEKEQAGRKVVAVIGDGAMTGGMVFEAMNHAGDLHNDMLVVLNDNEMSISENVGALNNHLAQLMSGRFYTTLREGGKKVLKGMPVIKEMAKRTEEHLKGMVVPGTLFEELGFNYIGPIDGHDVDALVETMRNMRNLKGPQVLHIMTKKGRGYEPAEKDPIGWHAVPKFDPSLFKKPATKPGLPTFSQVFGKWLCDIAEQDEKVLAITPAMREGSGMVEFSQRFPKQYFDAAIAEQHAVTLSAGFACEGFKPVVAIYSTFLQRAYDQLIHDVALQQLPVLFAIDRGGIVGADGPTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYCYDAGPSAVRYPRGCATGATQVEAMTALPIGKGVIKRVGKRIAILNFGTLLASALTAAESLDATVVDMRFVKPLDVDLVKEMAQTHEVLVTVEENAIMGGAGAGVLEQLQKLRMPKAVLQIGLPDEFIKHGSPEEVTHDLQLDAEGILAQINAYLAQ
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: Y7633_ORYSJ
Sequence: MSSPAQPPPTRPPVAAPPPSLAAAAPISVQPPPLQPKPPPHPQQPPQAVVSVGVGPPPPTPQHQQQQQGPPGHAPPQQRPRICFNAHCKDPKSDGPRRRGWRLRNGDFAELCDRCYHSFEHGGFCETFHLEVAGWRNCESCGKRLHCGCIVSVHAFVHLDAGGVECVMCARKSHAAMAPSQIWSSSMHMAQNVADRKDNFVKSWRPPAGQFSSQWRQNNMWSMSTMQSDLQQRLAFEFDRPSGSEKLLPGRTFIHAHEKKFDDMHDRSTTPAGMNQIMRERYANGHTQHTTLDPTYAYTLYHREGTNPNLHDHSHHAGENDHLTARKGVTSDPCSSVSTTFKLDSHHPSILKDDPSAVPAGLSSNFSSANGPKDHIRIGPTQQQQQMASSSLQKQFYSHSVIDNDFQAQLRNGRPRMDAKARSQLLPRYWPRITDQELQHLSGDSNSVITPLFEKMLSASDAGRIGRLVLPKKCAEAYFPAISQAEGLPLKVQDATGKEWVFQFRFWPNNNSRMYVLEGVTPCIQSMQLQAGDTVTFSRIDPEGKLVMGFRKATNLSAEQDQPTKPANGVLPPPEANNKVVVPDSSPNAAVPRPIKVNTESKSSSPVEQATACKIDKGALPQKEGPGTSSSSPLPVKRKATSVGPKIKRFHMDSEESMELKITWEEAQELLRPPPKAPSIVVVDGHEFEEYEEPPILGRRTYFVTDQSGENHQWAQCEDCSKWRKLPVDALLPSKWTCSDNKWDSERSSCDSAQEINMEELGEMIPIKPGAAKKTKGKVDTDNIDVSDGLDTLANLAILGEGESLPSQPTTRHPRHRPGCSCIVCIQPPSGKGPKHKQTCTCNVCMTVRRRFRTLMMRREKRQQSEKDSGVPRKREPGQSSEPVPQSGSGAHPTSTSSPHQRADTNGEGPEDMSIDNKRTSSPVKNQIDLNSQPEREDEQSPKSDATRLLRDNPT
What are the official names of this protein?
B3 domain-containing protein Os07g0563300.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_RALSO
Sequence: MRLILLGAPGAGKGTQAKFICERFGIPQISTGDMLRAAVKAGTPLGIEAKKVMDAGGLVSDDIIIGLVKDRLQQSDCKNGYLFDGFPRTIPQAEAMKDAGVPIDYVLEIDVPFDAIIERMSGRRVHVASGRTYHVKYNPPKNEGQDDETGDPLIQRDDDKEETVRKRLSVYENQTRPLVDYYSGWAENGNGAAKVAPPKYRKISGIGNVEDITGRVFGALEA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRP35_STAAC
Sequence: MMSQQDLPTLFYSGKSNSAVPIISESELQTITAEPWLEISKKGLQLEGLNFDRQGQLFLLDVFEGNIFKINPETKEIKRPFVSHKANPAAIKIHKDGRLFVCYLGDFKSTGGIFAATENGDNLQDIIEDLSTAYCIDDMVFDSKGGFYFTDFRGYSTNPLGGVYYVSPDFRTVTPIIQNISVANGIALSTDEKVLWVTETTANRLHRIALEDDGVTIQPFGATIPYYFTGHEGPDSCCIDSDDNLYVAMYGQGRVLVFNKRGYPIGQILIPGRDEGHMLRSTHPQFIPGTNQLIICSNDIEMGGGSMLYTVNGFAKGHQSFQFQ
What is the function of this protein?
Exhibits lactonase activity.  Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis (By similarity).
What are the official names of this protein?
Lactonase drp35.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SF3B3_DROME
Sequence: MYLYNLTLQKATGVTHAVHGNFSGGKQQEVLLSRGKSLELLRPDSNTGKVHTLLSTEIFGCVRALMAFRLTGGTKDYIVVGSDSGRIVILEYNPSKNALEKVHQETFGKSGCRRIVPGQYFAIDPKGRAVMIGAVEKQKLAYIMNRDTQARLTISSPLEAHKSNTLTYHMVGVDVGFDNPMFACLEIDYEEADMDPSGDAAQRTQQTLTFYELDLGLNHVVRKYSEPLEEHANFLVSVPGGNDGPSGVLICSENYLTYKNLGDQHDIRCPIPRRRNDLDDPERGMIFICSATHRTKSMYFFLLQTEQGDIFKITLETDDDVVSEIKLKYFDTVPPATAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDDEPEFSSAMPLEEGETFFFAPRALKNLVLVDELPSFAPIITSQVADLANEDTPQLYVLCGRGPRSTLRVLRHGLEVSEMAVSELPGNPNAVWTVKKRADDEFDAYIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLCCAALGDDALVQVYPDGIRHIRSDKRVNEWKAPGKKSITKCAVNQRQVVITLSGRELVYFEMDPTGELNEYTERSEMPAEIMCMALGTVPEGEQRSWFLAVGLADNTVRILSLDPNNCLTPCSMQALPSPAESLCLVEMGHTESTTQGGLDDDAPAQRSGNNKGTIYLNIGLSNGVLLRTVLDPVSGDLADTRTRYLGSRPVKLFRIKMQGSEAVLAMSSRTWLSYYHQNRFHLTPLSYETLEYASGFSSEQCSEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRTFVIHPDTGRMLIAETDHNAYTEDTKSARKEQMAEEMRSAAGDEERELAREMANAFINEVLPEDVFSSPKAGLGLWASQIRCLDAMHGQTMFSVPLTQNEAIMSMAMLKFSIAADGRYYLAVGIAKDLQLNPRISQGGCIDIYKIDPTCSSLEFMHRTDIDEIPGALCGFQGRLLAGCGRMLRIYDFGKKKMLRKCENKHIPYQIVNIQAMGHRVYVSDVQESVFFIRYRRAENQLIIFADDTHPRWVTATTLLDYDTIAIADKFGNLSIQRLPHSVTDDVDEDPTGTKSLWDRGLLSGASQKSENICSFHVGEIIMSLQKATLIPGGSEALIYATLSGTVGAFVPFTSREDYDFFQHLEMHMRNENPPLCGRDHLSYRSSYYPVKNVLDGDLCEQYLSIEAAKQKSIAGDMFRTPNQICKKLEDIRTRYAF
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome (PubMed:18981222).  SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (PubMed:18981222).  Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (By similarity).  May also be involved in the assembly of the 'E' complex (By similarity).  Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (By similarity).
What are the official names of this protein?
Splicing factor 3B subunit 3.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_PSEA6
Sequence: MALTKEDILNAIAEMPVMDLVELIEAAEEKFGVTATAAVAAAAPAAGGEAAAEQTEFDVVLTSFGGNKVAVIKAVRGATGLGLKEAKEVVEAAPKAIKEGVAKEEAEELKKTLEEAGAEVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y097_STAAR
Sequence: MEKNQRKKRSDAEYNQQIILTTMEDLLEQGEDISTKKMSDIAKISGVGVGTLYRHFESKTLLCQAIMDKKVDQMFIEIEDILAENTQWPVRDKINVILTKYLDLKEANFTTLNFIEKSSSHSSSVINIPFFERLKNLLIQQFENVHSIADLDFKLNLMLNAFSSDFYYFVKHNQKLTKQQFLDKLLDLYLK
What are the official names of this protein?
HTH-type transcriptional regulator SAR0097.
Protein: GLMM_BIFLS
Sequence: MPKMFGTDGVRGLANRDLTARLALDLGDAAVRVLGDAGTQDDQPEGRRRALVGRDTRVSGDFLASALSAGMSAGGFDVIDAGIIPTPGVAYLTSVLNVEIGAVISASHNPMPDNGIKFFARGGFKLPDQKEDDIEAVLGQDWDRPTGAGVGRVSHDQTTATNLYIDHLVATIAPLNDDKTQPKPLKGLKIVADCANGATSVVAPEALRRAGADVIVINASPDGYNINKNAGSTHPEQLQAMVKATDAVMGVAFDGDADRCLAVDEDGNMINGDQIMGILARAKQREGKLNHDTLVVTVMSNLGLKLALKDMGIKTVETAVGDRYVLEEMLKGGYSLGGEQSGHVINREFATTGDGTLTALTLCNEVVKSGKSLKELAADFPQLPQTLINVPNVDKKAAATNKRIQDAVAREEELLGDTGRVLLRPSGTEPLVRVMAEAATQAYADEVCTRLAKIVAEELAL
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y5023_MYCGI
Sequence: MPRTENDTWDLASSVGATATMVAAARAVATRAEDPVIDDPYAEPLVRAVGIDFFAKLASGELTPEDLDVSGDESPVGMSRFADGMAARTRFFDDFFTDACAAGVRQAVILASGLDARGYRLTWPEGMTLFEIDQPEVIEFKRTTLAGLGATPSTHLATVAIDLREDWPTALRDAGFDPSVPTAWIAEGLLGYLPPDAQDRLLDTIGELSASGSRLAVESVPSQQSADQDEMREKMKDSTDRWRSHGFDLDFSELVFLGERANVPDYLRERGWAVTATPTNDLLTRYGLAPLDTDEGFAEVVYVNAAR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mflv_5023.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: GSA_PELTS
Sequence: MYKGFDRSVSLYRQACKVIPGGVNSPVRAFKAVGLNPVFVKKGEGARIYDFDDNEYIDYVCSWGPLILGHRHPRVVGALERCLNEVGTSFGAPTELENILAEMIVEAVPSIEMVRLVNSGTEAAMSALRLARGYTGRNKIVKFEGCYHGHADFLLIKAGSGALTFGVPTSPGIPAAAAAGTIVARYNDLAGLEEIFKLEGEDIAAVIVEPVAGNMGVVPPAPGFLEGLRNLTARYGSLLIFDEVITGFRLAYGGAQELYGVAPDLTCLGKVIGGGLPVGAYGGRREIMEQVAPSGPVYQAGTLSGNPLAVSAGIATLEVLKQPGVYGRLEQTAAALEDALKQAARQTGAEVCFNRAGSMLCAFFTGEEVKDYASACTSDTARYAAFFRSMLEQGVYLAPSQFEAAFVSLAHGKEEIERTAEAARHAFKAAVEQK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYLC_YEAST
Sequence: MSSGLVLENTARRDALIAIEKKYQKIWAEEHQFEIDAPSIEDEPITMDSEELHRTYPKFMSSMAYPYMNGVMHAGHCFTLSKVEFSIGFERMNGKRALFPLGFHCTGMPILACADKLKREAELFGKNFDNVPAEEEEIKEETPAEKDHEDVTKFKAKKSKAAAKKGRGKYQFEIMLQLGIPREEIIKFADAKYWLTYFPPLCESDCTSLGARIDWRRSFVTTDANPYYDAFIRWQMNKLKAAGKIKFGERYTIYSEKDGQACMDHDRQSGEGVTPQEYIGVKIEALEFADDAAKIIDSSSDLDKSKKFYFVAATLRPETMYGQTCCFVSPTIEYGIFDAGDSYFITTERAFKNMSYQKLTPKRGFYKPIVTVPGKAFIGTKIHAPQSVYPELRILPMETVIATKGTGVVTCVPSNSPDDYITTKDLLHKPEYYGIKPEWIDHEIVPIMHTEKYGDLTAKAIVEEKKIQSPKDKNLLAEAKKIAYKEDYYTGTMIYGPYKGEKVEQAKNKVKADMIAAGEAFVYNEPESQVMSRSGDDCIVSLEDQWYVDYGEESWKKQAIECLEGMQLFAPEVKNAFEGVLDWLKNWAVCRTYGLGTRLPWDEKYLVESLSDSTIYQSFYTIAHLLFKDYYGNEIGPLGISADQMTDEVFDYIFQHQDDVKNTNIPLPALQKLRREFEYFYPLDVSISGKDLIPNHLTFFIYTHVALFPKKFWPKGIRANGHLMLNNSKMSKSTGNFMTLEQTVEKFGADAARIAFADAGDTVEDANFDESNANAAILRLFNLKEWAEEITKESNLRTGEITDFFDIAFEHEMNALIEKTYEQYALTNYKNALKYGLFDFQAARDYYREASGVMHKDLIARYIETQALLLAPIAPHFAEYIYREVLGNQTSVQNAKFPRASKPVDKGVLAALDYLRNLQRSIREGEGQALKKKKGKSAEIDASKPVKLTLLISESFPEWQSQCVEIVRKLFSEQTLDDNKKVREHIEPKEMKRAMPFISLLKQRLANEKPEDVFERELQFSEIDTVKAAARNVKKAAQALKIAEFSAISFPYGAKTGKDIFTGEEVEIPPVTKIVENAVPGNPGVVFQNI
What are the official names of this protein?
Leucine--tRNA ligase, cytoplasmic, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.