PharMolix/UniProtQA huggingface dataset:
Protein: PPX_PSEAI
Sequence: MDLQSMPQKPAEAFPLIAALDLGSNSFHLCLAKANIHGEVRILERLGEKVQLAAGLDEERNLSEEATQRGLDCLRRFAQFISGMPQGSVRVVATNALREARNRSDFIRRAEEVLGHPVEVISGREEARLIYLGVANSMPDSGGRRLVSDIGGGSTEFIIGQGFESELRESLQMGCVSYTQRYFRDGKITPARYAQAYTAARLELMGIENSLRRLGWQQAVGASGTIRAVALAIKAGGHGNGEISPDGLAWLKRKVLKLGDVEKLDLEGIKPDRRTIFPAGLAILEAIFDALELEQMVHSEGALREGVLYDLVGRHQHEDVRERTISSLMQRYHVDPEQASRVEAKALKVLAEVGDAWELNDELHRDLLSWGARVHEIGLDIAHYHYHKHGAYLIEHSDLAGFSRQDQQMLSLLVRGHRRNIPADKLAEFAAEGDKLVRLCIVLRFAILFHHIRGTQEMPSVRLKAEPKSLSVTFPEGWLEANPLTQADFAQEAEWLKRVGYSLNVR
What is the function of this protein?
Degradation of inorganic polyphosphates (polyP).  Releases orthophosphate processively from the ends of the polyP chain.
What are the official names of this protein?
Exopolyphosphatase, ExopolyPase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PIRC1_SALSA
Sequence: MGAGILRVIIMDSENYVETHPSDDNEAMKTSDVYKVDKNLPKRFNNPDCFQGYSTKINHPFYQTSSQIYGSKRPTVHEMPTTFNGSYRKFSEHMLKSGMFRDNGFNTSIEKSKITGHDTIPMFQDRINFNYAYDSGNGPKN
What is the function of this protein?
Microtubule inner protein involved in the attachment of outer dynein arms (ODAs) to dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.  Functions at the initial step of left-right asymmetry specification of the visceral organs.
What are the official names of this protein?
Piercer of microtubule wall 1 protein, Pierce1, UPF0691 protein C9orf116 homolog.
What is the protein family that this protein belongs to?
Belongs to the PIERCE1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: NSA2_NEOFI
Sequence: MHRLLRGGHLQSFHEYIERWQKQHGKRLDHDERVRKRQARESHKQSQDAQNLRGLRAKLYQQKRHAEKIQMRKRIKAQEEKNVKSSAPDEPSKTPLPQYLLDRSQATNAKALSSAIKDKRAEKAAKFAVPLPKVKGISEEEMFKVVNTGKKTHKKSWKRMITKPTFVGSDFTRRPVKYERFIRPMGLRYKKANVTHPELGVTVQLPILGVKKNPQNPLYTQLGVLTKGTIIEVNVSELGLVTTSGKVVWGKYAQITNTPENDGTVNAVLLV
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May play a part in the quality control of pre-60S particles (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein nsa2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PP2BC_HUMAN
Sequence: MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS
What is the function of this protein?
Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals.  Dephosphorylates and activates transcription factor NFATC1.  Dephosphorylates and inactivates transcription factor ELK1.  Dephosphorylates DARPP32.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, CAM-PRP catalytic subunit, Calcineurin, testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2B subfamily.
Protein: UTP25_MAGO7
Sequence: MGPRGRGGSRGGSFRGGGSRGRGRGRGRGGVNRFGKRPRFDSARVEDKEKESEEESLSEAEEDSEVPESESSDESVAEEAPTRPYMALLRSLSKGSGIKRRKLDHEPNNSEESGEDDSSESSADEDAPDDVCGDVDLVDEPEEDHDEIMEQERSDDEDEKDLTDSFNSHFASPDEVEVAERIKSITNHEWVSKRLPSKSARTVLTLPKQKDASDNASGPVPVTNPATLILKPKLKESITSQRPQLDASEQALAAPLFQYYDTLYCQRTVANGHNLRRLVCLHALNHIFKTRDRVIKNSAKLAKESADPDLEFRDQGFTRPKVLMLLPTRNSCAKMIEMMCSLTETDQQENRKRFDDSYVTREKQKFSNDKPTDFRDLFEGNADDMFRLGVKFTRKTIKFFSQFYNSDILLASPLGLRMAMGSTEEKNLDHDFLSSIEIVIMDQADAILMQNWEHVEHIFEHLNRQPKEAHGADFSRIRSWYLDGQSKNYRQTVILSSFNNPDLSEVMRVHCHNWQGKIRIQPDYQGVIQQLGVKVKQTFSRFDAQTIIADPDARFEYFIKAVVPSLTKRVKDSCGTLVFIPSYMDFVRVRNWFATSPAAQSLSFGVISEHTEVSETSRARSHFVTGRQKVLLYTERCHHFWRHQLRGVRRVIFYGLPDNPVFYKEIAGGCLGRSEQDMTLEPGEGSVRAMFSKYDVMKLERVVGTPRVGKMLHEKGDTFDFV
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SE6L2_MOUSE
Sequence: MGTPKAQHPPPSQLLLLILLSCAWIEGLPLKEDEMMPEPGSETPTVASEDLAELLHGALLRKGPEIGFLPGSDPDPTLATPPAGQTLAAPSLPRATEPGTGPLTTAVTPKGVRGAGPTAPELLTPPPGTTAPPPPGPASPVPPLRPEGGEEETTTTIITTTTVTTTVTSPVLCNNNISEGEGFVESPDLGSTASRSVELLDCTYSIHVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGNGFRIHYQAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPAWTGEPPSCTASCGGTIHNATLGRIVSPEPGGAAGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFPPFLAHGNVTTTDPEFHPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGLHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEITNGHRTASDAGFPVGSHVQYRCLPGYSLEGAAVLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEGGNLALAILLPLGLVIVLGIGVYIYYTKLQGKSLFGFSGSHSYSPITVESDFSNPLYEAGDTREYEVSI
What is the function of this protein?
May contribute to specialized endoplasmic reticulum functions in neurons.
What are the official names of this protein?
Seizure 6-like protein 2, Brain-specific receptor-like protein A, BSRP-A.
What is the protein family that this protein belongs to?
Belongs to the SEZ6 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=In cerebellar predominantly localized to the endoplasmic reticulum.
Protein: RL31B_CORJK
Sequence: MKKDIHPDYHPVVFKDASTGHQFITRSTATSDRTVEWEDGNEYPLIVVDVTSESHPFWTGAQRVMDTAGRVEKFQRRYGNMTRRKKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: TGT_XYLFA
Sequence: MSRLQFQLQATDGAARRGQLSFPCGTVQTPAFMPVGTYGAVKGVLPGQLCDLGAEIILGNTFHLFLRPGLEVIADHGGLHGFMRWNGPILTDSGGFQVFSLAHRRKISEQGVTFAAPTDGAQVFLGPEESMKIQKVLNSDIVMIFDECTPYPATEDVARDSMELSLRWAQRSRDAHDALDNDAALFGIIQGGVHPDLRGRSLDGLQAIGFDGYGIGGLAVGESESERNVILEYLHPRVPADRPRYLMGVGRPEDLVESVARGVDMFDCVMPTRHARNGQYFTGFGTVKIRNACYARDVDPIEPGCGCPACVGGYTRAYLRHLDRCNEMLASMLGTLHNLWYYETLMANMRAAITAGTFFAFRRSFYLARGLDLPPLPEVAGCAG
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ATPB_BURA4
Sequence: MSTAALVEGKIVQCIGAVIDVEFPRESMPKIYDALILDGSELTLEVQQQLGDGVVRTICLGASDGLRRGLTVKNTAKPISVPVGKPTLGRIMDVLGRPIDEAGPIESEHTRSIHQKAPAFDELSPSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELINNIAKEHGGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEHFRDEGLDVLFFVDNIYRFTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKKGSITSVQAVYVPADDLTDPSPATTFGHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVIGEEHYSITRRVQQTLQRYKELRDIIAILGMDELSPEDKLSVARARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMIVDGECDHLPEQAFYMVGTIDEAFEKAKKIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PP260_ARATH
Sequence: MSVVSSFHQSWKSLILASQRCNTVKQIKSTHSLFIIHGLHRNTYAISKLLTAFLHLPNLNKHFHYASSIFDSIEIPNSFVYDTMIRICSRSSQPHLGLRYFLLMVKEEEEDITPSYLTFHFLIVACLKACFFSVGKQIHCWVVKNGVFLSDGHVQTGVLRIYVEDKLLFDARKVFDEIPQPDVVKWDVLMNGYVRCGLGSEGLEVFKEMLVRGIEPDEFSVTTALTACAQVGALAQGKWIHEFVKKKRWIESDVFVGTALVDMYAKCGCIETAVEVFEKLTRRNVFSWAALIGGYAAYGYAKKATTCLDRIEREDGIKPDSVVLLGVLAACAHGGFLEEGRTMLENMEARYGITPKHEHYSCIVDLMCRAGRLDDALDLIEKMPMKPLASVWGALLNGCRTHKNVELGELAVQNLLDLEKGNVEEEEAALVQLSNIYFSVQRNPEAFKVRGMIEQRGIRKTPGWSLLEVDGIVTKFVSGDVSHPNLLQIHTLIHLLSVDASQIL
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g28660.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: YQHJ_ECOLI
Sequence: MKYLAFLIKGKTTHFDVGK
What are the official names of this protein?
Protein YqhJ.
Protein: RS14_LIMRJ
Sequence: MAKKSKIAKLHHQEALVKKYAEKRKELKAKGDYIGLSKLPRNSSAVRLHNRDRYDGRPHAYMRKFGMSRIKFRELAHKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ATPF_UREPA
Sequence: MKLNKKHLVAILSVLSLSIIVVPLLTSCTGDIPELNPAEIINTLFPNVWVFIAQVIAMCVVFSLVLWLVWKPTNKMLDKRREYIAKEITDAENAKQEALQYLENAKSEHLAAQAQTLEIIAKAKSESLTLRESLEKEAREAADKIISSAKISIANERRENLERLQSEAREAAYIAAEALMKKELSREDNDKLVDQFIKELENNEK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PROP_STAAS
Sequence: MDFNKENINMVDAKKAKKTVVATGIGNAMEWFDFGVYAYTTAYIGANFFSPVENADIRQMLTFAALAIAFLLRPIGGVVFGIIGDKYGRKVVLTSTIILMAFSTLTIGLLPSYDQIGLWAPILLLLARVLQGFSTGGEYAGAMTYVAESSPDKRRNSLGSGLEIGTLSGYIAASIMIAVLTFFLTDEQMASFGWRIPFLLGLFLGLFGLYLRRKLEESPVFENDVATQPERDNINFLQIIRFYYIDIFVCFVAVVFFNVTNYMVTAYLPTYLEQVIKLDATTTSVLITCVMAIMIPLALMFGKLADKIGEKKVFLIGTGGLTLFSIIAFMLLHSQSFVVIVIGIFILGFFLSTYEATMPGSLPTMFYSHIRYRTLSVTFNISVSIFGGTTPLVATWLVTKTGDPLAPAYYLTAISVIGFLVITFLHLSTAGKSLKGSYPNVDNEQDRAYYAEHPKEALWWVKERKN
What is the function of this protein?
May be a proton symporter involved in the uptake of osmolytes such as proline and glycine betaine.
What are the official names of this protein?
Putative proline/betaine transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ILVC_YERPS
Sequence: MANYFNTLNLRQQLAQLGKCRFMARDEFADEAGYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVAYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSAVVKAVQPLMKEGAALGYSHGFNIVEVGEQVRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVSEGTDAAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGAFSSGMMADWANDDVKLLNWREETGRTAFENAPQFEGKISEQEYFDHGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANAAVPLLKEKFMDSLQAGDLGKSIPGSAVDNAQLRDVNEAIRNHPIEAVGHKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: DER_RICRS
Sequence: MTKQIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTDGKIGSFEFLLIDTPGLDEHPNSMGKRLIEQTTKAILEADLICFMVDARSGILPDDKLLSSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMIAISAEHGTGLIDLYDEIIAKLPEEESIETNIADPIKGDCLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKKSTITESLEKLSASDTINSIKLANTVILMIDALAPLKQQDLNIASHVVNEGRSIVIVVNKWDLVKESEKEAFQEEFYYQINTHLPQVKGIPVLFISAINKQNIEQVLDACLKIYKIWNKKITTSKLNEWLNFTTEAHLLPLQKGGRRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYLVNNMREAFDMPGVPIRFTYVKTKNPYV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL35_STRPI
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHLRKASMVHSGDYKRIKAMLTRLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RSSA_TRIAD
Sequence: MSGGLDILRLTADDVSKMLAASAHLGTTNVDYQMEQYVFRRRTDGVHIIDLRQTWEKLLIAARIIASIENPADVCVLSARPYGQRAVLKFAKFTGASPIAGRFTPGTFTNQIQKAYREPRLLIVTDPRVDHQPITEASYVNIPVIAFCNTDSRLRYIDVGIPCNNKGAHAIGLMWWLLAREVLRLRGTISRDTDWEHMPDLFFYRDPEEVEKEEQAQNNKWAAPEQSPALSAAVPSSAAPVEEWSSSPSKETTEWGASNTAAAAKSSWSNETGGEWGAQEGGEWGS
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_PARPJ
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTAGGRKVINARRAKGRKRLAI
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SYY_LACLA
Sequence: MNIFDELKARGLVFQTTDEAALSKALTEDMVSYYVGYDPTADSLHLGNLVLILTMKRLQMAGHKPYALVGGATGLIGDPSFKDSERSLQTKDTVTKWSGKIRSQLERFLDFENGENKAEMTNNYNWFENLTFIDFLRDVGKHFTVNYMISKDSVKSRMESGISYTEFAYQIMQGYDFYELNQLHNVTLQLGGSDQWGNMTAGTELLRRKANKQGHVITIPLITDSTGKKFGKSEGNAIWLDADKTSPYEMYQFWLNVDDADAVKMLKIFTFLSLEEIAEIEEQFEAARHERLAQKVLAREVVSLVHGKAAYEQAVKTSEILFGGGDLRQLDAKSILTGLKAAPQHQVTDDEDLTLVELLISAGIAPSKRQAREDITNGAIYINGERVQALDYVITDSDKIENRLTVIRRGKKKNFVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEIKN_HUMAN
Sequence: MWPLRVYTRKKREGQRLNLTPTPDLGSPAKAEAPPGSKRKGKVHGLSKIAEKAERSRQGGSGSGPFSPRLGVTGEKSLQENRSSEDTQDEKIASLRESVTDDLQVDSSSSNSELVSGLSLHHGMASSLLSYSVTDSYAEYKSFEESFPSPELFRKSDYLDWECPNLEEHMQWKNSTLLDTSKAVAIEKAPQFSNVSAIFSTSSEDYQKCHRKTVMTVADQNVSPKAKCASNSESDNAACEILLAEKTCPSTPEKTKKKKTNSSTPGKKNRGLLTSTPSSETAGFVIDLSSVQKASFEELFPNVSNYVNSNEIVPVSSLQENSSNEFPANASEICCIIRTSPGTRQVKNKGVIVKKKKYSLPKDTPQDIIIKMA
What is the function of this protein?
Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage.  Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole.  Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway.  Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores.  Not required during meiosis II or mitosis.
What are the official names of this protein?
Meiosis-specific kinetochore protein.
What are the subcellular locations of this protein?
Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes at kinetochores in meiosis I but undetectable in meiosis II.
Protein: IF2_GLOVI
Sequence: MTNANMQGKIRIYDLARDLGRDNRDVMAVCQRLGIAHKTHSSTISEQEADSIREAFQRGLPPGGRKKAKIQQQGAAAANKQQILEVRRPPVGYQPPVRTEVSQILVSTVTPAVPTEAQPLPIPTLPELPVPEQVAEQAAAPSVQEAVEPIAVSPVTSPLPIDAADVEADNYTADEDSMPISIAQTVVEAPAAPTSEAAPPEPEPTPLPAPAAEAPQPVRPPAPPAPAKPTPAPAPAPRPTAEQPSEPRRPQPPAQPPSRPEKRGGPLIAPNRGGLQPTRPVPAQPAPQTPTRSGSGIAKKGAITKAGSGSGGGRPGGPMRRRDEREAAVVDEQPKILLLSGNISVQDLAQRMHVPTTEIIKTLFMKSVMVNINQTLDQATAELVARELGYEVQAETAVAQATKTEMLDVGDIESLEVRPPVVTIMGHVDHGKTSLLDAIRSARVAEGEAGGITQHIGAYQIEVPTEAGPRKLVFLDTPGHEAFTAMRARGAKVTDITVLVVAADDGVKPQTIEAISHAKAAGVPILVAINKVDKPDANPERVKQELTEYDLVPEEWGGKTVMVPVSAKQKLNLDLLLENLLLVADYELELMANPNRQAKGTIIEANLDKARGPVATALVQNGTLHVGDIIVVGSIFGKVRALYDDRGNRVDAAPPSMPVEVLGLTDVPQAGDEFEVYSDEREARRIADERTSKARENRLQQQMASRRVSLGAFSAQAQEGELKELALIIRADVQGSVEAIRASLEKLPQDKVQLRVLQAAAGEVSETDIDLAAASNAVILSFSTTLASGARQAAEQAGVDVREYDVIYKLLEDIQLAMEGLLDPELVEEALGGAEVRQVFPVGKGQVAGCYVKEGKLLRNAQMRVRRGKEVVFEGHVDSLKRFKEDAKEVATGFECGVGSDKFASWQPGDLIECFRMVTQKRTLN
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_SHEFN
Sequence: MSGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELTVEDMQHDLDRRRPGTSRYTTARREADEVRILSGVFEGKTTGTSIGLLIENTDQRSQDYSDIKDTFRPGHADYTYQQKYGMRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGIEIHGYLAQLGPISADTIDLTQIEQNAFFFPDASKLEALDEYMRGLRKSGDSIGAKITVAATGVPVGLGEPVFDRLDADIAHALMGINAVKGVEIGDGFGVVTQKGSQGRDLMSPQGFASNHAGGVLGGISSGQPVVAHIALKPTSSISVPGQSMTVQGETIDMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNQDVTSQTPVIGMR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PA2HC_TRIST
Sequence: GVIELTKMIVQEMGKNALTSYSL
What are the official names of this protein?
Basic phospholipase A2 homolog, svPLA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPF_BACC2
Sequence: MKVKICGITDVETAKCACEYGADAIGFVFAESKRKITLGLAKEIIGKLPAHVLKIGVFVNESVEVIQKIADECGLTHVQLHGDEENHQIRRLNIPSIKSLGVTSESDMKSAQAYETDYILFDSPKEKFHGGNGKTFSWELLEHMPKELRKKTILAGGLNILNIEEAIRTVRPYMVDVSSGVETEGKKDLKKIKQFIIKSKECSK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: NPM_RHIMB
Sequence: MASTASNTSKLEKPVSLIWGCELNEQNKTFVFKVSDEDKSEHQLALRTVCLGDKAKDEFHVVEIVPQVEGSDVQPVPIASLKPSILPMATMVGIELTPPVTFRLKAGSGPVYISGQHIALEEDYSWAEEEGEEEVEEEEEEEDPESPPKAVKRPAASKKGSQAKKKKMDKDEEESSEEDSPVKKGKGAGRGRKPAAKK
What is the function of this protein?
Acts as a chaperone for histones, such as histone H2A-H2B, and thus regulates the assembly of nucleosome cores.  Involved in chromatin remodeling, especially during fertilization and early embryonic development.  May be involved in sperm chromatin decondensation during fertilization.
What are the official names of this protein?
Nucleoplasmin.
What is the protein family that this protein belongs to?
Belongs to the nucleoplasmin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL22_OPITP
Sequence: MEVQALTRYARMSPKKMRDISRIIQGRKAAEAADYLALIPRKSARLIAKTLRSAIANAENNNNLSADALTVKLALIENGPVLKRFKAGARGSAMPRRKKMAHIRIVLTDGNSN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y644_CHLT2
Sequence: MRFLLKLLSKEKENILLEGFWVLEVRVTTKARENRVVCLEDGILRVRVTEVPEKGKANDAVVALLANFLSIPKSDVTLIAGEASRRKKVLLPRSIKAFLLEQFPSESSSTTGKKS
What are the official names of this protein?
UPF0235 protein CTL0644.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: GSHB_RHILO
Sequence: MKLKIAVQMDHISTVSIAGDTSFALSLEAQRRGHQLFHYTPDRLSLRDGKVFARIEEMQVRDEKGSHYSLGEKVRTDLSEMDVVLLRQDPPFDMNYITTTHILERIHPKTLVVNDPAWVRNSPEKIFVTEFADLMPDTLITKDPLEVAAFRKEFGDIIVKPLYGNGGAGIFHLHEADRNLASLLEMFGQLFREPYIVQRYLKDVRKGDKRIILIDGEPVGAINRVPAEHDSRSNMHVGGRAEKTELTEREREICARIGPSLRERGFILVGIDVIGDYMTEINVTSPTGVREVQRFGGADIASLFWDAVEGKRK
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: RL11_MYCTA
Sequence: MAPKKKVAGLIKLQIVAGQANPAPPVGPALGQHGVNIMEFCKAYNAATENQRGNVIPVEITVYEDRSFTFTLKTPPAAKLLLKAAGVAKGSAEPHKTKVAKVTWDQVREIAETKKTDLNANDVDAAAKIIAGTARSMGITVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.