PharMolix/UniProtQA huggingface dataset:
Protein: ATPD2_SYNC1
Sequence: MKSTAISRRYAKSLVNLAAPDGQLESTYTQLEQIQQAFACEPRLYKLLASPTLAADKIAGLLEGIGNYLQLSTTLRNLLGLLQQRQRLEYFDALVADYRELADVQLGLVRARVCSAAPLDAEVQQAISAQLQKRYGKQAVLELAVEPELLGGVRIEVAGQVLDGTIRSGLRRMAGYLNS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta 2, ATP synthase F(1) sector subunit delta 2, F-type ATPase subunit delta 2, F-ATPase subunit delta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GNRHR_HUMAN
Sequence: MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFSL
What is the function of this protein?
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH).  This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.  Isoform 2 may act as an inhibitor of GnRH-R signaling.
What are the official names of this protein?
Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANB_LEPIN
Sequence: MKNIHKIFSPEKKGKEKISVVTCYDFSFARILNETEIDSILVGDSLGMVFQGNTSTLPVTLEEMIYHTKAVRRGAPDKFLIADLPFLSYQTSIEEGIRSAGKIMKESDCDAVKIEGGSEFICELVSILKQIGVPVMGHLGLTPQSVHVFGGHRVQGKGEESSSKLLKESISLFESGVFSMVLEMIPAELGKKVSQEVGVPTIGIGAGSDCDGQVLVLNDLLGLDINFQPKFLKKFSNLHSIVKEAIADYDKEVKSGEFPGKDHSF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_LISMF
Sequence: MIEIEKPKIETIEISDDAKYGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVTSIQIDGALHEFSVIEGVVEDVTTMILNIKKLALKIYSDEEKTLEIDMQGPGVVTAADINYDSDVEILNPDLHIATLSDNAKFHVRLNATRGRGYTPADQNKRENMPIGVLPVDSIFSPVIRVNYQVENTRVGQSTNYDKLTFDVLTDGSISPEEAVSLGAKILSEHLSIFVNLTDEAQKAEIMIEKEESHKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELADKSEDDMMKVRNLGRKSLEEVKVKLADLGLSLRNEN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MIAA_BRUA4
Sequence: MNEGAITNAILIAGPTASGKSALAIRMAHETGGFIVNTDSMQVYDVLDLLTARPNKADLAAAEHHLYGHVAPSMSYSTGRWLDDVADLLTQPAMKHRTPIFVGGTGLYFRALLGGLSQMPEVPGDVRAYWRGRMEMDGPENLHRLLSERDPEMAATLQPFDSQRIVRALEVFEGTGKSLLVWQQTKGQALVDDHSARKIVLLPDRTWLSERIARRFALMWDNGAIDEVKALLVLDLDPALPAMKAIGVREITAFLQGSMSREEAIERSVIATRQYAKRQSTWFRNQLDDSWCTHANSDDAFAQLTTTK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SYWM_BOVIN
Sequence: MALRSMRKARECWNFIRALHQGPDAAPVPQKDAVKRIFSGIQPTGIPHLGNYLGAIESWVRLQDEHDSVLYSIVDLHSITVPQDPTILRQSILDMTAALLACGINPEKSILFQQSQVSEHTQLSWILTCMVRLPRLQHLHQWKAKTAKEKHNGTVGLLTYPVLQAADILLYKSTHVPVGEDQVQHMELVQDLAQSFNKKYGEFFPVPKSILTSMKKVKSLRDPSAKMSKSDPDKLATVRITDSPEEIVQKFRKAMTDFTSEVTYEPASRGGVSNLVAIHAAVAGLPVEEVVRRSAGMDTARYKLVVADAVIEKFAPIKSEIEKLKMNKDHLEKVLQVGSARAKELAYPVCQEVKKLVGFL
What is the function of this protein?
Mitochondrial aminoacyl-tRNA synthetase that activate and transfer the amino acids to their corresponding tRNAs during the translation of mitochondrial genes and protein synthesis.
What are the official names of this protein?
Tryptophan--tRNA ligase, mitochondrial, (Mt)TrpRS, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ISPF_BURO1
Sequence: MDFRIGQGYDVHQLVEGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDAAFKGADSRVLLRACAERVKAAGFTIQNVDSTVIAQAPKLAPHIDGMRANIAADLGLPLERVNVKAKTNEKLGYLGRGEGIEAQAAALLVKQGG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: GPX3_YEAST
Sequence: MSEFYKLAPVDKKGQPFPFDQLKGKVVLIVNVASKCGFTPQYKELEALYKRYKDEGFTIIGFPCNQFGHQEPGSDEEIAQFCQLNYGVTFPIMKKIDVNGGNEDPVYKFLKSQKSGMLGLRGIKWNFEKFLVDKKGKVYERYSSLTKPSSLSETIEELLKEVE
What is the function of this protein?
Involved in oxidative stress response and redox homeostasis.  Functions as a sensor and transducer of hydroperoxide stress.  In response to hydroperoxide stress it oxidizes (activates) the transcription activator YAP1, which is involved in transcription activation of genes of the oxidative stress response pathway.  May also play a direct role in hydroperoxide scavenging, being the most active of three closely related S. cerevisiae peroxiredoxins (GPX1, GPX2, and HYR1/GPX3) with respect to peroxide and lipid hydroperoxide reduction.  The three enzymes are not required for the glutaredoxin-mediated antioxidant function.  In the presence of peroxides, HYR1/GPX3 is directly oxidized at Cys-36 to form a cysteine sulfenic acid (-SOH).  Cys-36-SOH then forms either an intramolecular disulfide bond (Cys-36 with Cys-82) or a transient, intermolecular disulfide bond with 'Cys-598' of YAP1, which is further resolved into a YAP1 intramolecular disulfide bond ('Cys-303' with 'Cys-598'), which causes its nuclear accumulation and activation, and a reduced Cys-36 in HYR1/GPX3.
What are the official names of this protein?
Glutathione peroxidase-like peroxiredoxin HYR1, Glutathione peroxidase homolog 3, GPx 3, Hydrogen peroxide resistance protein 1, Oxidant receptor peroxidase 1, Phospholipid hydroperoxide glutathione peroxidase 3, PHGPx3.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space. Peroxisome matrix.
Protein: ASPD_ACIBT
Sequence: MKKLMMIGFGAMAAEVYAHLPQDLQLKWIVVPSRSIEKVQSQVSSDIQVISDIEQCDGTPDYVIEVAGQAAVKEHAQKVLAKGWTIGLISVGTLADSEFLVQLKQTAEKNDAHLHLLAGAIAGIDGISAAKEGGLQKVTYKGCKSPKSWKGSYAEQLVDLDHVSEPTVFFTGTAREAAMKFPANANVAATIALAGLGMDETMVELTVDPTINKNKHTIVAEGGFGQMTIELVGVPLPSNPKTSTLAALSVIRACRNSVEAIQI
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: YRS4_CAEEL
Sequence: MEETNAFSAFNQLLMSQNVVSPTKQPMELTNEKLMEFVRNAMQNQQGLPEVPNIIPSALPSMLSQIPTQPMPQMPVVIQTSQMNDVMGDQMLKASPSASSDMSSLDSDVADHPMTMMMQQQQDFQNPLQQLTIDSSANIAAGVNGNTEQRSSGRHETWLECFNTTKFAEYEALLFSVYVAERTDRKYDGWTYFDCLHRLQSKCRYRVRAKKQDEFYIIEEKGVHNHGAVEPVGQAGSHAGLPKTIREIVDRSYNENWPVEARTIKVDEEIQRLGLPENPRLGRQIDNRLAYLRRVKNLHETRRIQDQVNGTMVIKDPVKEAMLQALMEQNGGQLTVGQGFVDQIIANQGIPEMPIKKEEPTQPVESMEMAEQVAKPLAMNPSPDFFQFLQNQKLSHEHEQQQQQLHAAILAQAQAHAQAQAQAQQNLMESQKNIHQ
What are the official names of this protein?
Uncharacterized protein T05H10.4.
Protein: HA22D_ARATH
Sequence: MDKFWTFLTALHSGAGPIVMLLYPLYASVIAMESTTKVDDEQWLAYWIIYSFLSLTELILQSLIEWIPIWYTVKLVFVAWLVLPQFQGAAFIYNRVVREQFKKHGVLRSTHSKPTKPNILHSIFPHREGHEAHSH
What are the official names of this protein?
HVA22-like protein d, AtHVA22d.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1386_ARCFU
Sequence: MSITAFDTKIPQEFSHSFLVDFSGLFQYLLRPLSEIDENVRWFGRRFEDYLLALQVNVHDRSGLYPQCIPYLFGMTICPFEEVLTFGII
What are the official names of this protein?
Uncharacterized protein AF_1386.
Protein: HIS4_GEOKA
Sequence: MAAFTIYPAVDMRGGKCVRLLQGDYNKETVYGDSPVAMAEQFAAQGAEWIHMVDLDGAKEGRRVNDRFVIEAARRLSVHVQVGGGIRTEEDIVHYLENGVARVILGSAAISDPPFVKKMLQKYGRRIVIGIDARDGFVATEGWLATSNVKAEELGRMLAEAGAETFIFTDIATDGTLSGPNIAAAVRLAEATGKEVIASGGVSSLDDLRALCQYAGQGIGGAIVGKALYTNQFTLAEALKVVNER
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2R31_HUMAN
Sequence: MTTFIPIIFSSVVVVLFVIGNFANGFIALVNSIERVKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVFNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVILVMLLGPLLFLACQLFVINMKEIVRTKEYEGNLTWKIKLRSAVYLSDATVTTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVIFFLLLCAVYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVLRQVRYWVKGEKPSSP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).  Activated by the sulfonyl amide sweeteners saccharin and acesulfame K.
What are the official names of this protein?
Taste receptor type 2 member 31, T2R31, Taste receptor type 2 member 44, T2R44, Taste receptor type 2 member 53, T2R53.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL32_AFIC5
Sequence: MAVPRRKTSPSRRGMRRSADALKKPTYVEDKDSGELRRPHHLDLKTGMYKGRQVLKVKKED
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NIFH_DESRM
Sequence: MRQIAIYGKGGIGKSTTTQNTVAALAEAGKKIMVVGCDPKADSTRLLLHGLNQKTVLDTLRDEGEDIDLEDVLKTGYGDTKCVESGGPEPGVGCAGRGIITSINLLESLGAYTNDLDYVFYDVLGDVVCGGFAMPIREGKAREIYIVASGEMMALYAANNISKGVQKFANTGGVRLGGIICNSRKVDNELELLTAFAKELGSQLIHFVPRDNMVQRAEINKKTVIDFDPAQPQADEYRTLAQNIDGNDMFVIPKPMTQDRLEELLMAHGILD
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RLMN_MYCMM
Sequence: MAQELMFEEPRRGKPPRHLADFDAEGRASAVAALGLPPFRAKQLAHQYYGRLIADPRQMTDLPAAVREQIAETMFPNLLTAAREVTCDAGQTRKTLWRATDGVTLESVLMRYPQRNTVCISSQAGCGMACPFCATGQGGLTRNLSTAEILEQVRAAAAALRDEFGDRLSNVVFMGMGEPLANYARVLAAVRRITEPPPMGFGISARSVTVSTVGLAPAIRKLADERLGVTLALSLHAPDDELRDTLVPVNNRWKISEALEAAHYYAEVTGRRVSVEYALIREVNDQPWRADLLGKRLHRALGPLVHVNLIPLNPTPGSDWDASPKPVEREFVKRVRAQGVSCTVRDTRGREISAACGQLAAEGG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_JUNIN
Sequence: MAHSKEVPSFRWTQSLRRGLSQFTQTVKSDVLKDAKLIADSIDFNQVAQVQRALRKTKRGEEDLNKLRDLNKEVDRLMSMRSVQRNTVFKAGDLGRVERMELASGLGNLKTKFRRAETGSQGVYMGNLSQSQLAKRSEILRTLGFQQQGTGGNGVVRVWDVKDPSKLNNQFGSVPALTIACMTVQGGETMNSVIQALTSLGLLYTVKYPNLSDLDRLTQEHDCLQIVTKDESSINISGYNFSLSAAVKAGASILDDGNMLETIRVTPDNFSSLIKSTIQVKRREGMFIDEKPGNRNPYENLLYKLCLSGDGWPYIGSRSQIIGRSWDNTSIDLTRKPVAGPRQPEKNGQNLRLANLTEIQEAVIREAVGKLDPTNTLWLDIEGPATDPVEMALFQPAGSKYIHCFRKPHDEKGFKNGSRHSHGILMKDIEDAMPGVLSYVIGLLPPDMVVTTQGSDDIRKLFDLHGRRDLKLVDVRLTSEQARQFDQQVWEKFGHLCKHHNGVVVSKKKRDKDAPFKLASSEPHCALLDCIMFQSVLDGKLYEEELTPLLPPSLLFLPKAAYAL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: HEM3_MYCUA
Sequence: MIRIGTRGSLLATTQAAIVRDALIANGHAAELVTISTLGDRSSAPIETLGVGVFTTALREAIEDGRVDAAVHSHKDLPTAQDPRFTIAAIPPRQDPRDAVVARDGLVLGELPVGSLVGTSSPRRAAQFRALGLGLEIRPLRGNLDTRLNRVSNGDLDAIVVARAGLARLGRLDDVTETLEPVQMLPAPAQGALAIECRAGDSRLATVLAELDDADTRAAVTAERALLAELEAGCSAPVGAIAEVVESIDEEGRVFEELSLRGCVAALDGSDVIRASGIGTSGRARELGLAVAAELFELGARELMWGEGNSPQGS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CHEZ_BURM1
Sequence: MNEPIHAGPGDAPFGGDSQPEGADLASDRILARIGQLTRTLRDSMRELGLDKHVERAAEAVPDARDRLRYVATMTEQAAERVLNAIEIAKPVQERVQNEAEALDARWAQWYAAPIEHAEVRELMDDTRAFLRALPDATSATNAQLLEIMLAQDFQDLTGQVIKKIMDMVYLIEQQLLTVLVENIAPERREQFAATAAALAAEKTSATGSPESLLNGPQIAPEGKPDVVQDQAQVDDLLASLGF
What is the function of this protein?
Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
What are the official names of this protein?
Protein phosphatase CheZ, Chemotaxis protein CheZ.
What is the protein family that this protein belongs to?
Belongs to the CheZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_LACPL
Sequence: MSTMNLILMGLPGAGKGTQAQKILEDFDIPHISTGDIFRAAIKNETKMGLEAKKYIDAGNLVPDEVTNGIVRDRLAEADTKNGFLLDGYPRNIDQAHALKQIGEELNKPLDGVINIHVEPAVLVERLSGRFICRTCGATYHKLYNKPKVEGTCDVCGGHDFYQRDDDKPATVKNRLDVNIKLNTPLIDYYGQEKLLYNVDGDRDIDDVYKDIKKILDNL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VLPC_MESHY
Sequence: MKKSIFSKKLLVSFGSLVALASIPLIAISCGQTNTDKSQQPGSGSSTSGDQSGTTTGGHSGSGTSTSGGQSGTTSGSGTTTGEQTETAPKSPESGSQEATPKSPESGSQEATPKSPESGSQEAAPKSSESGSQEAAPKSSESGSQEAAPKSSESGSQKTT
What is the function of this protein?
Responsible for the antigenic diversity for host adaptation.
What are the official names of this protein?
Variant surface antigen C, VlpC prolipoprotein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MURI_GEOSW
Sequence: MERAIGVIDSGVGGLTVAKEIMRQLPKERIVYLGDTARCPYGPRPKEEIRQFTWEMTNYLLRYNIKMLVIACNTATAVVLDEIREQLDIPVLGVVHPGARAALKATKNGHIGVIGTIGTVKSGAYEKALKSINHRVRVESLACPKFVPLVESGNFEGEEARKIVAESLEPFKSSNMDVLILGCTHYPLLSPLIKEYMGKRVKLICSGDETAREVSAILHHSHLLYTGQREAEHLFFTTGSKELFQKIASKWFGKPIENVQTIEL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: SOXS_ECOLI
Sequence: MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSDYRHRL
What is the function of this protein?
Transcriptional activator of the superoxide response regulon of E. coli that includes at least 10 genes such as sodA, nfo, zwf and micF.  Binds the DNA sequence 5'-GCACN(7)CAA-3'.  It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters.
What are the official names of this protein?
Regulatory protein SoxS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_FUSNN
Sequence: MLNREDNQYQEKLLKISRVSKTTKGGRTISFSVLAAVGDGEGKIGLGLGKANGVPDAIRKAIAAAKKNIVKISLKNNTIPHEIAGKWGATTLWMAPAYEGTGVIAGSASREILELVGVHDILTKIKGSRNKHNVARATVEALKLLRTAEQIAALRGLEVKDILS
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HEMH_CAMC1
Sequence: MKKALLLLNMGGANSLDDVEIFLTNMFNDPYILGIKNKFLRKFVAFMITKGRLKTAKHNYEQIGGKSPLCELTAKLCEKISSLKSEFDAVDFAMNYTSPFVKDVLKKYEKFDEIVLLPLYPHHSQTTITSSLADFKKAKEELKLKAKISLCEPFYDDDTYNKIIISHIREAIKDTDISDVSLIFSAHSLPRKIIEKGDIYEKHINEHVQILSKMLKEQGLNFKDVSLAYQSRLGPVKWLEPSLNEALAKCENKKALIYPLSFCIDNSETIFELVIEYAKLAKELSFSFYKVVECPNFSDEFASFILEKSKNAREFSL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMLI_STRVP
Sequence: MRDHTDEKSEAAGNDDGHVRIGGLPAFDPDDPAENAVINRLVGNWHRRAAVKREEPDVYALFDPGRPDFREDMIPFRGHPIWERLSDETRSRLLSWGWVAYNRNTVLIEQRIANPAFELVIGGAYPGLGGQQLELAVAQAMVDEQYHTLMHINGSAVTRRMRRSDFSDRVLPDSHITTIHQEHLDRCEEPWQRSLTTLGFATVAEISINAYLDLLADDQEIQVVNSTTVKLHNRDEYCHASISGEMMKQVYEALPADRRRFLLEKVVAGLEAFVAPDFTTWESIVAFEGVPGWEKAAAEVREAQGGTHLVQDHSGIHTLLTEMDVLDQVEFGWGTTVTR
What is the function of this protein?
Involved in chloramphenicol biosynthesis (PubMed:24347692, PubMed:25564306).  Catalyzes the six-electron oxidation of an aryl-amine precursor of chloramphenicol (NH2-CAM) to yield the aryl-nitro group of chloramphenicol (CAM) (PubMed:24347692, PubMed:25564306, PubMed:27203126).  During catalysis, upon exposure of the diferrous cluster to O(2), ClmI forms an exceptionally long-lived peroxo intermediate (CmlI-peroxo), which reacts with NH2-CAM to form CAM (PubMed:25564306, PubMed:27203126).
What are the official names of this protein?
Alpha-N-dichloroacetyl-p-aminophenylserinol N-oxygenase, Non-heme di-iron N-oxygenase.
What is the protein family that this protein belongs to?
Belongs to the AurF N-oxygenase family.
Protein: YOEF_ECOUT
Sequence: MAGVRQHGWRAIPAVCSEYGADTLPDRYRSDGRCLLFRQQAGISALKQELEVKTPYRAMNHPVIGVVTKADLASMEQISLVKSWLREAGAHNVLVTSAVNNNGVTELFALLHTEEGCC
What are the official names of this protein?
Uncharacterized protein YoeF.
Protein: GLPK_MYCPN
Sequence: MDLKQQYILALDEGTSSCRTIVFDKDLNQVAIAQNEFNQFFPKSGWVEQDPLEIWSVQLATMQSAKNKAQIKSNNIAAVGITNQRETIVLWNKENGLPVYNAIVWQDQRTASLCDKLNQDTKIKEFVKKHTGLPINPYFSATKIAWILENVPLAQKMLKEDKLLAGTIDTWLIWKLTGGKMHVTDVSNASRTLLFDITTMTWSQELGDIFKVPLSILPKVMPSNAHFGDIVPSHWSTSATGMVPIRGVAGDQQAALFGQLCVEPAMVKNTYGTGCFMLMNIGNELKYSQHNLLTTVAWQLENQKPVYALEGSVFVAGAALKWLRDSLKVMYSAAESDFYAKLAQKEEQEVVFVPAFTGLGAPYWDASARGAIFGIEANTKREHLVKATLEAIAFQANDLIKAMASDLNSSIKKIKADGGACNSNYLMQFQADIANLEVIIPKNVETTTMGAAFLAGLAVNYWKDTKQLEKLTGIAKQFKSQMNQTVREKKSKRWNEAVKRTLKWASLD
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: LICH_RAT
Sequence: MQLLGRVICFVVGILLSGGPTGTISAVDPEANMNVTEIIMHWGYPEHSVQTGDGYILGVHRIPHGRKNQFDKGPKPVVYLQWRHGFLADSSNWVTNIDNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEYWAFSFDEMAKYDLPASINYILNKTGQEQLYNVGHSQGCTIGFIAFSQMPELAKKVKMFFALAPVLSLNFASGPMVKLGRLPDLLLEDLFGQKQFLPQSAMVKWLSTHICTHVIMKELCANIFFLICGFNEKNLNMSRVDVYTTHCPAGTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPPLYSIKDMQLPTALWSGGKDWLADTSDINILLTEIPTLVYHKNIPEWDHLDFIWGLDAPWRLYNEVVSLMKKYQ
What is the function of this protein?
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol.
What are the official names of this protein?
Lysosomal acid lipase/cholesteryl ester hydrolase, Acid cholesteryl ester hydrolase, LAL, Cholesteryl esterase, Lipase A, Sterol esterase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: MDH_PECCP
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGYSGEDAKPALAGADIVLISAGVARKPGMDRSDLFNVNAGIVRNLVEQIAVTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPQDINVPVIGGHSGVTILPLLSQVPGISFSEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGESGVVECAYVESDGKHARFFAQPVLLGKDGVVERKDIGTLSAFEQNALSSMLDTLKQDIELGETFIKN
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.