PharMolix/UniProtQA huggingface dataset:
Protein: IF3_PROM2
Sequence: MPPRPRFDRRAPVRELPNINERIKYPQLRVVDSDGKQLGVIDRLKALEIANQRELDLVLVSEKANPPVCRIMDYGKYKFEQEKKAKEARKKSHQTEVKEVKMRYKIDKHDYDVRIGQATKFLKSGDKVKCTVIFRGREIQHSNLAETLLLKMASDLEEQSEVQQKPKREGRNMIMFLSPRKSPLIKKDNE
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLID_AERCA
Sequence: MAITSAGAGSGIDLESVISASVSAKKAQLQQPIITKQNSTQITLSGIGQLKSSISAFTDILDKLSAPGAFNKRAINITQSKDDPILKVEGKSGASNGQYNIIVNKLAETSRQEGIFDSSTTPLATQDGQLTFKAGDKTFKVDVKAGDTLQDIRKSINSNGDNFGLSVNIVNTADGKAKLVIDSGISGDGKDLTITGDNAELGVFEAGGGVMSQTRAASSAEINVDGNVLKSDTNTFDDSIQDLKVTVLRVSDKDSAGDLKANKVDITTDKTSIQELVQQFVDGYNTLQDKMNSLGKRNTFVGGVKQDDGGALAGDSTTRAIESFMSNLLVSPSQNSGTYSTVFEIGIKMDNKGKLSLDKTKFGEAVDKNFDQVVALFGGEKGLASTLNSGLKEYTKSGGMLAQREDVLNSDLRALTQKTATANAQLTKYEAALRAQYGSLDALLVKMNSSASALATLQTSYQKS
What is the function of this protein?
Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament.  Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
What are the official names of this protein?
Flagellar hook-associated protein 2, HAP2, Filament cap protein, Flagellar cap protein.
What is the protein family that this protein belongs to?
Belongs to the FliD family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RP132_VAR67
Sequence: MKKNTDSEMDQRLGYKFLVPDPKAGVFYRPLHFQYVSYSNFILHRLHGILTVKRPLLSFKNNTERIMIEISNVKVTPPDYSPIIASIKGKSYDALATFTVNIFKEVMAKEGISITKISSYEGKDSHLIKIPLLIGYGNKNPLDTAKYLVPNVIGGVFINKQSVEKVGINLVEKITTWPKFRVVKPNSFTFSFSSVSPPNILPTRYRHYKISLDISQLEASNISSTKTFITVNIVLLSQYLSRVSLGFIRRSLSYDMPPEVVYLVNAIIDSAKRLTESITDFNIDTYINDLVEAEHVKQKSQLTINEFKYEMLHNFLPHMNYTPDQLKGFYMISLLRKFLYCIYYTSRYPDRDSMVCHRILTYGKYFETLAHDELENYIGNIRNDIMNNHKNRGTYAVNIHVLTTPGLNHAFSSLLSGKFKKSDGSYRTHPHYSWMQNISIPRSVGFYPDQVKISKMFSVRKYHPSQYLYFCSSDVPERGPQVGLVSQLSVLSSITNILTSEYLDLEKKICEYIRSYYKDDISYFETGFPITIENALVASLNPNMICDFVTDFRRRKRMGFFGNLEVGITLVRDHMNEIRINIGAGRLVRPFLVVDNGELMMDVCPELESRLDDMTFSDIQKEFPHVIEMVDIEQFTFSNVCESVQKFRMMSKDERKQYDLCDFPAEFRDGYVASSLVGINHNSGPRAILGCAQAKQAISCLSSDIRNKIDNGIHLMYPERPIVISKALETSKIAANCFGQHVTIALMSYKGINQEDGIIIKKQFIQRGGLDIVTAKKHQVEIPLENFNNKERDRSNAYSKLESNGLVRLNAFLESGDAMARNISSRTLEDDFARDNQISFDVSEKYTDMYKSRVERVQVELTDKVKVRVLTMKERRPILGDKFTTRTSQKGTVAYIADETELPYDENGITPDVIINSTSIFSRKTISMLIEVILTAAYSAKPYNNKGENRPVCFPSSNETSIDTYMQFAKQCYEHLNPKLTEKELSDKIFCEKILYDPETDKPYASKVFFGPIYYLRLRHLTQDKATVRCRGKKTKLIRQANEGRKRGGGIKFGEMERDCLIAHGAANTITEVLKDSEEDYQDVYICENCGDIAAQIKSINTCLRCSKLNLSPLLTKIDTTHVSKVFLTQMNARGVKVKLDFERRPPSFYKPLDKVDLKPSFLK
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 133 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: CUED1_HUMAN
Sequence: MTSLFRRSSSGSGGGGTAGARGGGGGTAAPQELNNSRPARQVRRLEFNQAMDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEGGGSSGGVYEDSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHVFDRPYPLAPPTPPPRIDALGSGAPTSQRRYRNWNPPLLGNLPDDFLRILPQQLDSIQGNAGGPKPGSGEGCPPAMAGPGPGDQESRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESQKSKSSSVAVGNDFGFSSPVPGTGDANPAVSEDALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAASTANLLDDVEGHACDEDFRGRRQEAPKVEEGLREGQ
What are the official names of this protein?
CUE domain-containing protein 1.
Protein: HISX_CLOAB
Sequence: MEDIIRIIQDGSLDGEKYFQSLKERQGKENAEIIKTVKFIIDNVKENGDKALIEYTSKFDKVELQSIEVTKEEIKAAYSKVENDFICALKTAKENIEEYHSKQVQNSYVITKENGIVMGRTVRGLDKVGIYVPGGTAAYPSSVIMNAVPAKVAGVNKIIMTTPPMKDGFVNPSILVAADLAGVDKIYKVGGAQAIAALAFGTETIDKVDKIVGPGNIFVAMAKKSVYGFVDIDMIAGPSEILVISDETGNPKFIAADLMSQAEHDTLASSILVTTSKELIGKVIEEIKLQVEGLSRKEIILEALRNFGAIILVDSISRAIEIGNVVAPEHLEIITPNPFEYLNDIKNAGSIFLGSYSPEPLGDYMAGPNHVLPTSGTARFSSPLSVDDFVKKSSYLYYSEKALRNVNDKVVKIAETEGLTAHANSIKVRFK
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: HEPG_ASPOR
Sequence: MTAKVGINGFGRIGRIVFRNSFSHENTEVVMVNDPFIEVQYAAYMLKYDSTHGNFEYDVHIDGDSIVVNGKKVKFYAEKDPAKIPWKDAGAEYIIESTGVFTTVEKASAHLQGGAKKVIISAPSADAPMYVMGVNEKTYAGADVVSNASCTTNCLAPLTKVLHERFGVVEGLMTAVHAYTATQKLVDAPSKKDWRGGRAAAQNLIPSSTGAAKAVGKVIPELQGKVTGMSIRVPTSNVSVVDLTCRLEKGASYEEIITAIKEAAQGELKGILDYTEDDVVSSDMKGNPHSSIVDIKAGISLNPNFLKIVSWYDNEWGYSRRVLDLTAYIASVGK
What is the function of this protein?
Glyceraldehyde-3-phosphate dehydrogenase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing (PubMed:30466366).  The GAPDPH hepG/gdpB shows much higher resistance to HA than the GAPDH gpdA located outside of the cluster, but it does not seem to act in self-resistance (PubMed:30466366).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase B, GAPDH, Heptelidic acid biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Protein: PGLX1_EMENI
Sequence: MKLSHLLTSAVSVLSLGLTVEGHFSRSRNDAVGPKRPFKPLPYSHPRKKVCHVRSHGDGRDDSAFILSALKSCNNGGKVVFAEEKEYTIGTALDLTFLKHVDLEILGRIQFTNDTDYWQANSFKHTFQNATTFFQLGGEDVNVYGGGTLDGNGQIWYDLYAEDPLILRPILFGVIGLHGGTIGPLKLRYSPQWYQLVANSSDVLFDGIDISGYSKSENEAKNTDGWDTYRSKNIVIQNSVINNGDDCVSFKPNSTEILVQNLYCNGSHGISVGSLGQYIGEVDIVKNVLVYNISMYNASDMARIKVWPGVASAMSEDLQGGGGLGSVSNITYEDMYIENVDWAIEITQCYGQKNMTLCNEYPSNLTISDVYISNMYGTTSSARDPNIGTIVCSSPDVCSNIYVENIDVVSPSGTNDFICTNVNESLLQVNCTSG
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Exopolygalacturonase X-1, ExoPG, Galacturan 1,4-alpha-galacturonidase, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDC_BURP1
Sequence: MDIKRTVLWVIFFMSAVMLFDNWQRSHGRPSMFFPNVTQTNTASNATNGNGASGASAAAAANALPAAATGAAPATTAPAAQAQLVRFSTDVYNGEIDTRGGTLAKLTLTKAGDGKQPDLSVTLFDHTANHTYLARTGLLGGDFPNHNDVYAQVAGPTSLAADQNTLKLSFESPVKGGVKVVKTYTFTRGSYVIGVDTKIENVGAAPVTPSVYMELVRDNSSVETPMFSHTFLGPAVYTDQKHFQKITFGDIDKNKADYVTSADNGWIAMVQHYFASAWIPQSGAKRDIYVEKIDPTLYRVGVKQPVAAIAPGQSADVSARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGFVGNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQALRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLASVEMRGAPWVLWIHDLSQRDPYFILPVLMAVSMFVQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRTLGGAAAKKKAS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPRT_ASFP4
Sequence: MLHLIYISIIVVLIIILISYTRKPKYFRITAPRSVALFHGIHPLKPKNYKTFSEEFETILNNAIEDGDFKGQLTEPCSYALRGGKYIRPIILMEIVRACQLQHSFGAPIYPAEAALAVEYFHVASLIIDDMPSFDNDVKRRNKDTVWARFGVAKAQMSALALTMQGFQNICRQIDWIKEHCPRFPDPNQLGALLCTFVSHSLNSAGSGQLVDTPEKTIPFFKIAFIMGWVLGTGTIEDIGMIERAAHCFGNAFQLADDIKDHDTDTGWNYAKIHGKRKTFDDVAQSLQECKKILHGKKIYTSIWNEIFQKVINVALGT
What is the function of this protein?
Trans-prenyltransferase that catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with different allylic diphosphates, such as dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), farnesyl diphosphate (FPP) and geranylgeranyl diphosphate (GGPP), farnesyl diphosphate being the best allylic substrate.
What are the official names of this protein?
Trans-prenyltransferase, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranyltranstransferase, Polyprenyl-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family. Asfivirus trans-prenyltransferase subfamily.
What are the subcellular locations of this protein?
Host endoplasmic reticulum. Host membrane; Single-pass membrane protein.
Protein: DQX1_HUMAN
Sequence: MTSQPLRLAEEYGPSPGESELAVNPFDGLPFSSRYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQEVASTRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLRAFWGNPPIVHIPREPGERPSPIYWDTIPPDRVEAACQAVLELCRKELPGDVLVFLPSEEEISLCCESLSREVESLLLQGLPPRVLPLHPDCGRAVQAVYEDMDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAPEALMQALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPGFTRPPLSAEEAALRRALEHTDGDHSSLIQVYEAFIQSGADEAWCQARGLNWAALCQAHKLRGELLELMQRIELPLSLPAFGSEQNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHVAQLSSYCCYRSRRAPARPPPWVLYHNFTISKDNCLSIVSEIQPQMLVELAPPYFLSNLPPSESRDLLNQLREGMADSTAGSKSSSAQEFRDPCVLQ
What are the official names of this protein?
ATP-dependent RNA helicase DQX1, DEAQ box polypeptide 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBL_MONCA
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PPAT_STAAN
Sequence: MVQSLHEFLEENINYLKENGLYNEIDTIEGANGPEIKINGKSYINLSSNNYLGLATNEDLKSAAKAAIDTHGVGAGAVRTINGTLDLHDELEETLAKFKGTEAAIAYQSGFNCNMAAISAVMNKNDAILSDELNHASIIDGCRLSKAKIIRVNHSDMDDLRAKAKEAVESGQYNKVMYITDGVFSMDGDVAKLPEIVEIAEEFGLLTYVDDAHGSGVMGKGAGTVKHFGLQDKIDFQIGTLSKAIGVVGGYVAGTKELIDWLKAQSRPFLFSTSLAPGDTKAITEAVKKLMDSTELHDKLWDNAQYLKNGLSKLGYDTGESETPITPVIIGDEKTTQEFSKRLKDEGVYVKSIVFPTVPRGTGRVRNMPTAAHTKDMLDEAIAAYEKVGKEMKLI
What are the official names of this protein?
Putative pyridoxal phosphate-dependent acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: SCAI_MOUSE
Sequence: MVRGARQSQQPRSRLAPRLSGTVEKPPRKRKSRTEFTLKETMSSGGAEDDIPQGERKTVTDFCYLLDKSKQLFNGLRDLPQYGQKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLKRWQIGEIASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYSQVNKEDRPELVVKKLRYYARFIVVCLLLNKMDVVKDLVKELSDEIEDYTHRFNTEDQVEWNLVLQEVAAFIEADPVMVLNDDNTIVITSNRLAETGAPLLEQGMIVGQLSLADALIIGNCNNQVKFSELTVDMFRMLQALEREPMNLASQMNKPGIQEPADKPTRRENPHKYLLYKPTFSQLYTFLAASFKELPANSVLLIYLSATGVFPTGRSDGEGPYDFGGVLTNSNRDIINGDAIHKRNQSHKEMHCLHPGDLYPFTRKPLFIVVDSSNSVAYKNFTNLFGQPLVCLLSPTAYPKALQDQSQRGSLFTLFLNNPLMAFLFVSGLSSMRRGLWEKCQEYLRKINRDIAQLLTHSRSIDQAFLQFFGDEFLRLLLTRFVFCSATMRMHKAFRETRNYPESYPQLPRDETVENPHLQKHILELASILDVRNIFFENSMDDY
What is the function of this protein?
Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.  May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1.
What are the official names of this protein?
Protein SCAI, Suppressor of cancer cell invasion protein.
What is the protein family that this protein belongs to?
Belongs to the SCAI family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus. Cytoplasm. Note=Nuclear localization is required for inhibition of MRTFA.
Protein: KASSO_PHLMA
Sequence: MLTLKKSMLLLFFLGMVSFSLADDKREDEAEEGEDKRADEGEEKRAAEKKRFLEGLLNTVTGLLG
What is the function of this protein?
Induces contraction of smooth muscle in isolated guinea pig urinary bladder (EC50=4. 66 nM).  Has no antimicrobial activity against the Gram-positive bacterium S. aureus, the Gram-negative bacterium E. coli and the yeast C. albicans.  Elicits histamine release from rat peritoneal mast cells.
What are the official names of this protein?
Kassorin-M, PreproKassorin-M.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: C5AP_STRP8
Sequence: MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPAAEQAVETPQPTAVSEEVPSSKETKTPQTPDNAEETVADKANDLALQAPAKTADTPATSKATIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENPQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYEIQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTLEVATSATFSTEDRRLTLASKPKTSQPIYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQAPDKKPEAKPEQDGSGQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASARDQLPTTNDKDTNRLHLLKLVMTTFFFGLVAHIFKTKRQKETKK
What is the function of this protein?
This virulence factor of S. pyogenes specifically cleaves the human serum chemotaxin C5a at '68-Lys-|-Asp-69' bond near its C-terminus, destroying its ability to serve as a chemoattractant.
What are the official names of this protein?
C5a peptidase, SCP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: HIP43_ARATH
Sequence: MTVKKVEIKVDINCGKCNSAIMEAVTEIEGVNHISLDEGNSILTVVGTMDPVCVATRLKKIKQKPVIISVGPPPKPPEPPKPPEPEKPKPPPAPEPPKHVCKPPYCNSCDVVSVTTYESGSGCTIL
What is the function of this protein?
Heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 43, AtHIP43.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: LT_POVK6
Sequence: MDKTLSREEAKQLMQLLCLDMSCWGNLPLMRRQYLVKCKEYHPDKGGNEESMKLLNSLYLKLQDSVSSVHDLNEEEDNIWQSSQIPTYGTPDWDEWWSQFNTYWEEELRCNESMPSSPKRSAPEEEPSCSQATPPKKKHAFDASLEFPKELLEFVSHAVFSNKCITCFVVHTTREKGEVLYKKLLQKYQCSFISKHAFYNTVLIFFLTPHKHRVSAINNFCKGHCTVSFLFCKGVNNPYGLYSRMCRQPFNLCEENIPGGLKENEFNPEDLFGEPKEPSLSWNQIANFALEFDIDDVYYLLGSYIRFATKPEECEKCSKNDDATHKRVHVQNHENAVLLQESKSQKNACTQAIDRVIAERRYNCLTLTRKKLLTKRFKKLFNEMDKIVVGERKILLYMASIAWYTGLNKKIDELVVRFLKLIVDNKPKHRYWLFKGPINSGKTTLATALLNLCGGKALNINIPSEKLPFELGVALDQYMVVFEDVKGQIGIEKQLPSGNGVNNLDNLRDYLDGCVEVNLEKKHVNKRSQIFPPGIVTMNEYCIPETVAVRFEKTVMFTIKRNLRESLEKTPQLLSQRILHSGIAMLLLLIWYRPVSDFDEEIQSNVVYWKEVLDNYIGLTEFATMQMNVTNGKNILEKWFE
What is the function of this protein?
Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation.  Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA.  Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.  Participates in the modulation of cellular gene expression preceeding viral DNA replication.  This step involves binding to host key cell cycle regulators retinoblastoma protein RB1/pRb and TP53.  Induces the disassembly of host E2F1 transcription factors from RB1, thus promoting transcriptional activation of E2F1-regulated S-phase genes.  Inhibits host TP53 binding to DNA, abrogating the ability of TP53 to stimulate gene expression.  Plays the role of a TFIID-associated factor (TAF) in transcription initiation for all three RNA polymerases, by stabilizing the TBP-TFIIA complex on promoters.  Initiates viral DNA replication and unwinding via interactions with the viral origin of replication.  Binds two adjacent sites in the SV40 origin.  The replication fork movement is facilitated by Large T antigen helicase activity.  Activates the transcription of viral late mRNA, through host TBP and TFIIA stabilization.  Interferes with histone deacetylation mediated by HDAC1, leading to activation of transcription.
What are the official names of this protein?
Large T antigen, LT, LT-AG.
What are the subcellular locations of this protein?
Host nucleus.
Protein: EFG_STRS7
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAHPIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAVAETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIAYLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIAGMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_METM5
Sequence: MKGLGSTIVRSLPNGARLVCADNTGAKELEVIAVKNYVGTVRRLPAGGVGHMVFVSVKKGTPEMRKQVLPAIIIRQKKEYKRADGTRVKFEDNAAVIVTPEGTPKGSEIKGPVSKEAAERWPGVSRLAKIIH
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NDHK_STAPU
Sequence: MVINSELFRSSNSFQEEGFESVTNGLSFSITEENISDSVILTTFHDFTNWIRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLIITAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAIIDAVIKLRKKVGQETAHEKKNYQQSQRCFTMSHRLKPVLPIHTGTYDQQTLRRTPGIEMDTSLEYPLERILQNSIETSSPFQDSEEIGLLKDWKQSNQKQEQNVKMMKEEEA
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: DAPB_METVS
Sequence: MVKVAVTGALGRMGSGIIQKILETEGLNVVAAIDIPNHPKKGHDIGELIGIGKLGVNLSTSDELESVLKSSGAEVLVDFTAPAPCVNTAKIASKCGVNLVIGTTGFTKEQKDEMEKAIFENKVAATISQNYAVGVNIFFKTLELLAQKLGEYDIEIVEMHHKFKKDAPSGTALRAAEIIQENLNRNSNLIYGREGITGERTKEEICIHALRGGDVVGDHTVIFANDGERLELSHKASSRQSFIAGVILAIKFVGTKKEGIFNTFDVLGLN
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI_SULDN
Sequence: MKKILFLFTASLLLHVTLQAAKISDVASIVGVRDNHLIGYSLVVGLQKTGDGTTSKFTLQSIANMLKAMNIDMKPIDIKSKNVAAVVVTAELAPFARQGDKINITVSSIGDAKSLEGGTLLMTPLKGVDGKIYALAQGAVSIGGRNGKGAGDSHPTAGLIYDGGLVEREIAIDLYNQDYVTLSLKDANFQNSVSIQKTLNGYYSTEVAVAMDSRTVKLKKPSNKTMIEFLAEVQEINMDYNVQDRIVINERTGTIISGVGIHIKPIIMTHGDITIKITEQENPDKPAGSMVVDENMVIGLNENELYTKEGTTTVANLVRSLQKLGATPKDIISILEAMKSAGSISAELKLI
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.