PharMolix/UniProtQA huggingface dataset:
Protein: ODFP2_MACFA
Sequence: MSASSSGGSPRFPSCGKNGVTSLTQKKVLRAPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKNPPRCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERMKEEKDYTILQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLARQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRVRDWQKGSHELTRAGARIPR
What is the function of this protein?
Seems to be a major component of sperm tail outer dense fibers (ODF).  ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.  May have a modulating influence on sperm motility.  Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles.  Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes.  Required for the formation and/or maintenance of normal CETN1 assembly (By similarity).
What are the official names of this protein?
Outer dense fiber protein 2, Cenexin, Outer dense fiber of sperm tails protein 2.
What is the protein family that this protein belongs to?
Belongs to the ODF2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell projection, cilium, flagellum. Note=Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.
Protein: ATPA_STRMU
Sequence: MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARACGLDNAMSGELLEFDNGTFGMAQNLESSDIGIIILGDFNSIREGDTVKRTGKIMEVPVGQSLIGRVVNPLGQPVDGLGEIETTATRPVEAAAPGVMQRQSVSEPLQTGIKAIDALVPIGRGQRELVIGDRQTGKTSIAIDAIINQKGQDMICIYVAIGQKESTVRSQVEVLRKYGALDYTIVVTASASQPSPLLYIAPYAGVAMAEEFMYNGKHALIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKLSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSDLDSATQAKLNRGRRTVEVLKQGLHKPLAVEKQVLILYALTHGFLDSVPVDDILTFQDDMFDYIDSHDADIFETIRTTKDLPEEAVLDKAIQTFKDQSQFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RUVC_HALHL
Sequence: MTRILGIDPGSRVTGYGIVDDGRPTRLVTEGTLRLPRQAGLAERLGRIFDGLAELIAEHRPQEVALEQVFVHRNADTALKLGHARGAALTACVQAGLPVAEYAPARIKQAIAGSGRADKTQVGYMVRALLRLRTSPAEDAADALAAALCHAHHRSAPLTAATTGARR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PDE6D_DROPS
Sequence: MGSDDQSAADKIQKGFQINYMILRDADSGKIIWQENKDFSAPDVEHEARVPVKILDMRAVSREINFSTVESMENFRLDQKVLFKGRIMEEWFFEMGFVGASTTNTWQSTIEAAPESQMMPAKVLNGNVTIQTSFYDNETLITKSVVRLYYI
What are the official names of this protein?
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y5150_DICDI
Sequence: MKFDFLLANDGNNIPNKQIKEDKSSPYEFTSNPNKLDPYSNNINNNNNNNNNNKSSIPSSVSLSSISSISSMPISTSLSLSSPSIVISNNNPVLSNEYQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPVKTVNKKNSKSNKSNANKNNNNINNNNNNYTSMYDNKIQQQLQSIYKQQQQQQQQQYQTQTQTQTQTQTQTQTQTQTQTQTQNSSGGILNINSSINNNLNIYNNTSSNKFKHQHNQQAYNQNLSEINNSRNVTTSSVNANSNINPYPNSNSSINITTTTTTTTNNEILWTTTKPTSSTKHSVILSPPKKIDSYDSPQSSPPRQSSLLISTSSPPSPPLSPIQPTNIVQSSSSSFSSPTYIQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQVETVNNIGNNKSNHTSLTPNLTSLSTKDYPPMYSLNNNNSININNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKINNNHFDLNDYQDDNQSSYSSPDITTTHNRYSQQQQQQNNNNQSNYHIDHLNDKSIMKPTKKQIKKQSQPQEKLSKYSEDQIHEESEFLLASILLNLKDSNSTLPINNNNYNNNIGNFNNSTILKNISTTSSDDIGSSNNDYINGSISNEQHQYYSNKYSNQNYVQIDENNNNKNNKNNYVTNNIVNSNTDNYNYYSSHNDFDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNNSRNNYNNNSKKRSSSVQISPYPPSKSRI
What are the official names of this protein?
Putative uncharacterized protein DDB_G0282129.
Protein: IF5_PONAB
Sequence: MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDSGTGKKEKEKKNRKGKDKENGSVSSSETPPPPPPPNEISPPPHTMEEEEDDDWGEDTTEEAQRRRMDEISDHAKVLTLSDDLERTIEERVNILFDFVKKKKEEGVIDSSDKEIVAEAERLDVKAMGPLVLTEVLFNEKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEDDEDENIEVVYSKTASVPKVETVKSDNKDDDIDIDAI
What is the function of this protein?
Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S. mRNA. Met-tRNA[F]. eIF-2. GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide.  The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S. mRNA. Met-tRNA[F]) (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 5, eIF-5.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: ISPE_SHEPA
Sequence: MTASLSLGWPAPAKLNLFLHINAQRHDGYHELQTLFQFIEHCDYLDFKVLDTPKLKLHSNMSSAVADSDNLILKAAKSLQQRTDCQLGAEIWLDKRLPMGGGLGGGSSDAATTLVALNQLWETGLSLRELGEIGLKLGADVPVFINGFSAFAEGVGEKLQNVEPAEPWYLVLTPQVHVSTAEVFQDPDLPRNTPKLSLESLMNSPWQNDCQTLVAKRYPQVAKTLAWLLEYAPSRMTGTGACVFGQFEQEQEAKDVLAKLPASIQGFVAKGANISPLMLRLAQC
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PALI_YEAST
Sequence: MVSMIHIVVFLLAITTMFEILPLITVPVTKYLSLSSFRNHYYGLFGWCVRGQNQELMCTKMKIGYDSTDVDSSGHVLTLPSNSKVVVSNLLVVHPISLAFTGTLLILAVIIMVTPLGDSPEMLLFTALFSLPTFMLCLLCFLVDILLFISKLDWPGWLMLAATISVALCCSMLWVMRRVVSVKKYESQQSIAHACSMEQYSISDIYQSKQNGNSSEYEVAPTHTDSLIAPEVTYRGFIE
What is the function of this protein?
Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth.
What are the official names of this protein?
pH-response regulator protein palI/RIM9, Regulator of IME2 protein 9.
What is the protein family that this protein belongs to?
Belongs to the palI/RIM9 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AK1A1_CHICK
Sequence: MSAGCDFVALYNGQKIPLIGLGTWKSEPGQVKEAVKYALSVGYRHVDCAAAYSNEAEIGDAFQECVGPNKVIKREDLFVTSKLWNTKHHPEDVEPALRKTLADLKLDYLDLYLMHWPHAFERGDNLFPKNPDGTMRYDYTDYKDTWKAMEKLVEKGLAKAIGLSNFNSRQIDDVLSVATVKPAVLQVECHPYLAQNELIAHCQKRGLVVTAYSPLGSPDRMWKHPDEPVLLEEPGIKKLAEKYKKSPAQILLRWQAQRKVVTIPKSVTPARILQNLQVFDFSLTEEEMSHVGSLNKNWRYIVPMLTVNGKPVPRDAGHPNYPFNDPY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols.  Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids.  Acts as an aldehyde-detoxification enzyme (By similarity).  Displays no reductase activity towards retinoids (By similarity).
What are the official names of this protein?
Aldo-keto reductase family 1 member A1, Alcohol dehydrogenase [NADP(+)], Aldehyde reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Apical cell membrane.
Protein: HPRT_CHICK
Sequence: MATHSPCIVIGDDEQGYDLDLFCIPKHYADDLEKVYIPHGLIMDRTERLAREIMKGMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDKSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMKTLLSLLKQYNPKMVKVASLLVKRTPRSVGYRPDFVGFEVPDKFVVGYALDYNEYFRDLNHICVISETGKQKYKA
What is the function of this protein?
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate.  Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_SALPC
Sequence: MSKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGICVILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGNWHFATFNLADSAICIGAALIVLEGFLPKPTAKEQA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FTSA_STAAM
Sequence: MEEHYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREKNDVQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLDYVTINYHDNEETEEDVIDVKDKDNESKLGGFDWFKRKTNKKDTHENEVESTDEEIYQSEDNHQEHKQNHEHVQDKDKDKEESKFKKLMKSLFE
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: STX1B_BOVIN
Sequence: MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTTDIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL
What is the function of this protein?
Potentially involved in docking of synaptic vesicles at presynaptic active zones.  May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity).
What are the official names of this protein?
Syntaxin-1B, Synaptocanalin I, Syntaxin-1B2.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: KDSA_XYLFA
Sequence: MKLCGFEVGLNQPLFLIAGPCVIESLQLQLDTAGVLKEITSKLGLNFIFKSSFDKANRTSGSSFRGPGLEEGLKVLEAVKTQIGVPVLTDVHEYTPIDEVATVVDVLQTPAFLVRQTDFIRNVCAVGKPVNIKKGQFLSPWDMKPVVEKAKSTGNSQILVCERGASFGYNNLVSDMRSLAVMRETGCPVVFDATHSVQLPGAQGGRSGGQREFVPVLARAAVAVGISGLFAETHPDPPNALSDGPNAWPLHTMAMLLETLVELDAVTKKRGFLEQD
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GD_HHV23
Sequence: MGRLTSGVGTAALLVVAVGLRVVCAKYALADPSLKMADPNRFRGKNLPVLDRLTDPPGVKRVYHIQPSLEDPFQPPSIPITVYYAVLERACRSVLLHAPSEAPQIVRGASDEARKHTYNLTIAWYRMGDNCAIPITVMEYTECPYNKSLGVCPIRTQPRWSYYDSFSAVSEDNLGFLMHAPAFETAGTYLRLVKINDWTEITQFILEHRARASCKYALPLRIPPAACLTSKAYQQGVTVDSIGMLPRFIPENQRTVALYSLKIAGWHGPKPPYTSTLLPPELSDTTNATQPELVPEDPEDSALLEDPAGTVSSQIPPNWHIPSIQDVAPHHAPAAPSNPGLIIGALAGSTLAVLVIGGIAFWVRRRAQMAPKRLRLPHIRDDDAPPSHQPLFY
What is the function of this protein?
Envelope glycoprotein that binds to the potential host cell entry receptors TNFRSF14/HVEM and NECTIN1.  May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL (By similarity).
What are the official names of this protein?
Envelope glycoprotein D, gD.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein D family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs.
Protein: LEUC_AKKM8
Sequence: MGKTLFQKIWDAHTVGILPDGRTQMFIATHLLHEVTSPQAFGMVRDLGLTVRHPERTFATVDHIIPTDNQAEPFADATADAMIRELRRNCAENGIRFFDLPTGLQGIVHMVGPELGITQPGMTIVCGDSHTATHGAFGAIAMGIGTTQVRDVLATQTLALSPLKVRRINVNGKLAPGVRAKDVALHIIGLLGAKGGLGFAYEYGGEVIDAMSMDERMTLCNMSIEGAARCGYVNPDRTTVEYIKGRLFAPTGADWDKAVERWLGFASDADAEYDEIVEIDGASIEPTLTWGISPDQNTGISGSTPNPSDAADDDERKMINEALEYMKFPADMPLKGLPVQVCFVGSCTNGRISDFREVAALIKGRHVAPGIRALAVPGSQMTARQCEEEGIADIFREAGFEWRLAGCSMCLAMNPDKLQGDQLCASSSNRNFKGRQGSPTGRTLLMSPAMVAAAALTGKVSDAREVFSLN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CRCB_SALPA
Sequence: MLQLLLAVFIGGGTGSVARWMLSMRFNPLHQAIPIGTLTANLLGAFIIGMGFAWFNRMTHIDPMWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVLINLLGSFAMTALAFWLFSAAAAR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPB_STAAE
Sequence: MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKGADVAIDFSNPNLLFPLLDEDFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKENVTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLM5_HUMAN
Sequence: MWLSPSLLLLILPGYSIAAKITGPTTVNGSEQGSLTVQCAYGSGWETYLKWRCQGADWNYCNILVKTNGSEQEVKKNRVSIRDNQKNHVFTVTMENLKRDDADSYWCGTERPGIDLGVKVQVTINPGTQTAVSEWTTTTASLAFTAAATQKTSSPLTRSPLKSTHFLFLFLLELPLLLSMLGTVLWVNRPQRRS
What are the official names of this protein?
CMRF35-like molecule 5, CLM-5, CD300 antigen-like family member D, CMRF35-A4.
What is the protein family that this protein belongs to?
Belongs to the CD300 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Cell surface localization requires the ITAM-bearing Fc receptor FCER1G to overcome ER retention.
Protein: DAPA_KLEP7
Sequence: MFTGSIVALVTPMDENGNVCRTSLKKLIDYHVANGTSAIVSVGTTGESATLSHEEHGDVVMMTLELADGRIPVIAGTGANATAEAISLTKRFNDSGVVGCLTVTPYYNRPTQEGLFQHFKAIAEHTDLPQILYNVPSRTGCDMLPETVGRLAEIKNIVGIKEATGNLSRVHQIKELVSDDFILLSGDDATGMDFMQLGGVGVISVTANVAAREMADMCRLALAGQFAEARAINQRLMPLHTKLFVEPNPIPVKWGCKALGLVATDTLRLPMTPITDHGREAVTAALKHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_THEON
Sequence: MELSYQEKLTLIKLNELKKAKFDELVEKTGLDQVAVMRAVLWLQSKGLARLHEKSERIAKLTETGKKYAQIGLPEWRALKVLRKKGKVTLDDLKEVLSEDELKPIVGLLRKEGWASIRKEDGKLVLEITENGLKAEERAIDRALKLLAEKEAIPVSEIEEIIKVNDLKRRKIAEEDIVTERTVEITPEGEELANKGLELKEEVSTLTPELIKSGKWREVEFKRFNIQAPVRRIYPGKKQPYRAFLDKIRRRLIEMGFIEMTVDSLIETQFWNFDALFQPQNHPAREWTDTYQLKYPKSGYLPNKELVERVKTAHERGLAGSRGWGYVWSPERAMLLMPRAHGTALSGRQLAKGVEIPGKYFTIQRVFRPDVLDRTHLIEFNQVDGFVVGEDLNFRHLLGILKRFAVEIAGAKKVKFLPDYYPFTEPSVQMSAYHPELGWVEFGGAGIFREEMTRALGIDVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLGWLREARLVW
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCAMK_PEA
Sequence: MEYGTRKLSDVYEVSEILGRGGFSVVRKGTRKSNNDDEKSQSQSKSQSQSQVAIKTLRRLGTSNNLPRKKDGGENSTETMMKFPTMRQVSVSDALLTNEILVMRRIVENVSPHPNVIDLYDVYEDTNGVHLVLELCSGGELFDRIVAQDKYSETEASTVVHQIVAGLEAIHRANIIHRDLKPENCLFLDVGKDSSLKIMDFGLSSVEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSLGVILYILLSGYPPFIAQNNRQKQQMILNGNFSFYEKTWKGISQSAKNLISSLLTVDPAKRPSAQELLSDPWVKGEKAKDDQMDPEIVSRLQRFNARRKLRAAAIASVWSSTIFLRTKKLKSLVGSYDLKEDEIENLRMHFKKICADRDNATLCEFEEVLKAMKMPSLIPFAARIFDLFDNNRDGTVDMREILCGFSSLKNSKGEDALRLCFQMYDTDRSGCITKEEVASMLRALPYDCLPTDITEPGKLDEIFDLMDANSDGKVTFDEFKAAMQRDSSLQDVVLS
What is the function of this protein?
Protein kinase that recognizes the calcium spiking induced by Nod factors and translates this signal to components controlling nodulation and mycorrhizal infection responses.
What are the official names of this protein?
Calcium and calcium/calmodulin-dependent serine/threonine-protein kinase, Ps-SYM9, PsCCaMK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: QUEF_HELP2
Sequence: MTPELNLKSLGAKTPYIFEYNSQLLEAFPNPNPNLDPLITLECKEFTSLCPITSQPDFGVIFIRYIPKDKMVESKSLKLYLFSYRNHGSFHESCINTILLDLVRLLEPKYLEVYGDFASRGGIAIKPFVNYAIKEYQGFKEKRLLNAK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_CAMC5
Sequence: MNSEFVEVAIIGRCVGLKGCVKLHNKGDFPEQFKKNAVFFDKDGNEFIIKSYDVSKETALFEGYEDIDLAKSLVNKILYTTKELTRKNCKLKEGEFFYFDVLGLNIVENGEILGVVKDIEDNLNNALLYVKTSDDLVSIGFAKNFYVPYIDRFVISVSLENKEILTKDAKSILENS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADK_ECOLI
Sequence: MHPTGPHLGPDVLFRESNMKVTLTFNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVVDNHGASYTYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKIGAVSVPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKLAPATSSLSLSQIIADNTSLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILASERAYCARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQRCTCMLGATPFVYDLLNVLEKQPADLSALRFFLCGGTTIPKKVARECQQRGIKLLSVYGSTESSPHAVVNLDDPLSRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNVFMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVRGGENISSREVEDILLQHPKIHDACVVAMSDERLGERSCAYVVLKAPHHSLSLEEVVAFFSRKRVAKYKYPEHIVVIEKLPRTTSGKIQKFLLRKDIMRRLTQDVCEEIE
What is the function of this protein?
Catalyzes the esterification, concomitant with transport, of exogenous fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids.  Is maximally active on C6:0, C8:0 and C12:0 fatty acids, while has a low activity on C14-C18 chain length fatty acids (PubMed:15213221, PubMed:19477415).  Is involved in the anaerobic beta-oxidative degradation of fatty acids, which allows anaerobic growth of E. coli on fatty acids as a sole carbon and energy source in the presence of nitrate or fumarate as a terminal electron acceptor (PubMed:12535077).  Can functionally replace FadD under anaerobic conditions (PubMed:12535077).
What are the official names of this protein?
Medium-chain fatty-acid--CoA ligase, Acyl-CoA synthetase, ACS, Fatty acyl-CoA synthetase FadK.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Partially membrane-associated.
Protein: RM48_HUMAN
Sequence: MSGTLEKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGILLSISRPYKTKPTHGIGKYKHLIKAEEPKKKKGKVEVRAINLGTDYEYGVLNIHLTAYDMTLAESYAQYVHNLCNSLSIKVEESYAMPTKTIEVLQLQDQGSKMLLDSVLTTHERVVQISGLSATFAEIFLEIIQSSLPEGVRLSVKEHTEEDFKGRFKARPELEELLAKLK
What are the official names of this protein?
39S ribosomal protein L48, mitochondrial, L48mt, MRP-L48, Mitochondrial large ribosomal subunit protein mL48.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL48 family.
What are the subcellular locations of this protein?
Mitochondrion.