PharMolix/UniProtQA huggingface dataset:
Protein: PXA1_YEAST
Sequence: MSTTLAAPAKLKSLLLNLHTHCIGLHVNDVTPKVYFKLLIRHLLQISRSNAAHPKLRRRAQILLVSLFLSGVTLFSGVTYSTFKIILKCYKFYKFPWKRRNRRPLIRRTRSQMQLDSGARIMYIPEVELVDRQSPDDNKFMNATDKKKRKRIFIPPKDNDVYEHDKFLFKNVELERAKNSQLFYSKFLNQMNVLSKILIPTVFDKNFLLLTAQIFFLVMRTWLSLFVAKLDGQIVKNIIAGRGRSFLWDLGCWFLIAVPASYTNSAIKLLQRKLSLNFRVNLTRYIHDMYLDKRLTFYKLIFDAKASNSVIKNIDNSITNDVAKFCDATCSVFANIAKPVIDLIFFSVYLRDNLGTVGVAGIFVNYFITGFILRKYTPPLGKLAGERSASDGDYYNYHLNMINNSEEIAFYQGTAVERTKVKELYDVLMEKMLLVDKVKFGYNMLEDYVLKYTWSGLGYVFASIPIVMSTLATGINSEEKNMKEFIVNKRLMLSLADAGSRLMHSIKDISQLTGYTNRIFTLLSVLHRVHSLNFNYGAVPSILSIRTEDASRNSNLLPTTDNSQDAIRGTIQRNFNGIRLENIDVIIPSVRASEGIKLINKLTFQIPLHIDPITSKSNSIQDLSKANDIKLPFLQGSGSSLLILGPNGCGKSSIQRIIAEIWPVYNKNGLLSIPSENNIFFIPQKPYFSRGGTLRDQIIYPMSSDEFFDRGFRDKELVQILVEVKLDYLLKRGVGLTYLDAIADWKDLLSGGEKQRVNFARIMFHKPLYVVLDEATNAISVDMEDYLFNLLKRYRFNFISISQRPTLIKYHEMLLEIGENRDGKWQLQAVGTDEAITSIDNEIEELERKLERVKGWEDERTKLREKLEII
What is the function of this protein?
Involved in the import of activated long-chain fatty acids from the cytosol to the peroxisomal matrix.
What are the official names of this protein?
Peroxisomal long-chain fatty acid import protein 2, Peroxisomal ABC transporter 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: NPS10_HETAN
Sequence: MSSVSIQIPLPTPPPTQAHNSQTFCAPPLGSLTLPEVFDWHSKNSPNHPLYSYINIDGSIRTITWAESVRAVHRAARRMRTELGLSSDSVPDLTAGKPVVGILAVLDSITYSTLVTGVQYAGFTPFPISPRNSHAAVVHLINKAFVSHIIVEESCRGLLEDAFQSLKSDLTSPSMPTTSVAPVFEDLYVSSDSAQGEASVAFETPAWDSNAIIIHSSGSTAFPKPIAWTHGRAMQLSTVPWYGERDLTGKRMACHAMPMYHTMGYLLLAWAASSGLVLNGFRPQSPATKSTIENVFSASLEAHSDIIFTVPSFVEAWSKNPAYVKTLAELDGVMFGGGPLGKQVGDVLVSANVTLFNLYGSTEAGVLSSTVPADFNIDWEYFRISDIAKVAFVPNEENKLELVVLSSNLNTPSVFNAVYEDVPAYATSDLFEPHPTKPGYWKIFGRTDDQIMHSTGEKTNPGPLEHILNQDPHVRASLMFGRGQFQAGVLVDPTSEYRFDPSDEEKLAEFRNLIWPSVEEMNAYAPQHSRVFKEMILVSSPSKPFTFTAKNSVRRQAVIQEYDDEIKAIYFAVDETGRADIPSPTAWDSAKTLGFIRAVVQKVMKKEVQDGDDFFQHGCDSLQATWIRNTILRSLKDSTDANTQDISNSFIYQHPSVASLASFVSSVAQGQNNINSGLDRAQEMNIMVARYSKDFPPHVPSAPQPSKDTILLTGSTGALGSNILALLIASPSVARIYAFNRKSRSSIPLLDRQKSALLERGLDPSLAASKKVVLVEGDVTKQDLGISTELLSEIRVSITHIIHNAWPVNFNLSLESFEPQVKGLRHLVDLSLSSPHPSPPRVLFTASIGMFNDITRAEPVKEVPIGANVAVSNGYGESKWVGETILAEAAKQTPLRSTSIRVGQLSGGINGAWTTAEWLPSLVRSAIHLKALPDCEGDVSWIPVNVAAAAIVDFCQSDSSIMNLVHPRPATWSSIFSAFASVLNIPLVPYTEWLALLRKSAEDAGDAPDADSLQQNPGLRLLDWYHSAFVHENDSAYQYADTMGFPKFDMTNSLRASGTLADEGLPQLGESDVKLWVDYWKKVGFFPA
What is the function of this protein?
Adenylate-forming reductase, a natural product biosynthesis enzyme that resembles non-ribosomal peptide synthetases, yet serves to modify one substrate, rather than to condense two or more building blocks.  The A-domain preferentially accepts phenylpyruvic acid and benzoic acid as substrate.  The natural product of the enzyme is not yet known.
What are the official names of this protein?
Adenylate-forming reductase Nps10, Nonribosomal peptide synthase-like enzyme 10, NRPS-like, Phenylpyruvate reductase.
What is the protein family that this protein belongs to?
Belongs to the adenylate-forming reductase family.
Protein: RPOC_ANAMF
Sequence: MKMLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKIFGPVNDDECLCGKYRKKRYRGIVCEKCGVEVTSSKVRRERMGHIELVSPVAHVWFLKSLPSRIGALLDMPMKSIESILYSGDFVVIDPMTTPFSKGEVISESVYNQARDAYGDEGFIALTGAEAIRELLVRLDLGAIRAGLRSELESTSSEMKRKKVVKRLRIIENFIASGNRPEWMILTVIPVLPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLEKLLKLNPPAIMIRNEKRMLQEAVDGLFDSSRRSYVSSRAGSMGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPGLKLHQCGLPKKMALELFKPFICSKLKMYGVAPTVKLANKMIQSEKPEVWDVLDEVIREHPILLNRAPTLHRLGLQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILSPSNGRPIIVPSKDIVLGIYYLTLQRAQAPDQEVMSFGELSHVEYALHEGIVHTSSKIKYRMQRCNSDGTIVSEVVETTPGRLILWQIFPQHKDLTFDLVNQVLTVKEITSIVDLVYRSCGQRETVEFSDKLMCLGFQYASQSGISFGCKDMIIPDTKAAHVENASEKIKEFSIQYQDGLITRSERYNKVVDEWSKCTDLIARDMMKAISLSDEEGKLNSIYMMANSGARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLSVFEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCTVVEYDCKTKDGVVARAVIEGGAVVATLDSVVLGRVAAVDTYNPVTEELLLSAGELIDEGKVEKIRVAGLDAVRVRSPLTCESKKGICSLCYGRDLAVGDLVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVEVSNLIAVLDAEVKLVNSNVVTDKYGNQIVMSRSCEVVLLDSVGNEKMRHSVPYGAKLYVSDGQPVKMMDKMAEWDPYTIPIITEKTGTIKYVDLIYGVSINEVLDESTGISNRVVIDWKLHLQGANLRPRLVLLDEDGNIATLYNDLEASYFVPIGAVLNVQDGQKVHAGDVITRIPRESIKTRDITGGLPRVIELFEARRPKEHAIVSDVDGYVEFGKDYYRSKRRIFIRPVDKSLPAVEYLVPKGKHTIVNEGDFVHKGDLLMDGDPDQHDILRVLGAEALASYMISEIQQVYRLQGVRIDNKHIEVILRQMLQKVEITDPGDTMYLVGEHAGREEVMRLNRKLEEAGKKPVAYVPILQGITKASLDTNSFISAASFQETTKVLTEAAFSGKEDPLYGLKENVIVGRLIPAGTGFIMNKVKKLAMLDQSDYATYYNSELREIMGDLGDELIAEGEAASPGRSGDGYLGNGGGVVDY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PSB7B_ARATH
Sequence: MSQSSVDIPPKGGFSFDLCKRNDMLTQKGLKAPSFLKTGTTIVGLIFKDGVILGADTRATEGPIVADKNCEKIHYMAPNIYCCGAGTAADTEAVTDMVSSQLRLHRYQTGRDSRVVTALTLLKKHLFSYQGHVSAALVLGGVDITGPHLHTIYPHGSTDTLPFATMGSGSLAAMSVFEAKYKEGLTRDEGIKLVAEAICSGIFNDLGSGSNVDICVITKGHKEYLRNYMEPNPRTYVSSKGYSFTKKTEVLLTKITPLLERVEIVEVAGEAMEE
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit beta type-7-B, 20S proteasome beta subunit B-2, Proteasome component FC, Proteasome subunit beta type-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YDHL_SHIFL
Sequence: MAEQLEFFPVQSPCRGICQSDERGFCRGCFRSRDERFNWNKMSDGEKQEVLRLCRQRLMRKLRANKPASSDEPEQPSLF
What are the official names of this protein?
Uncharacterized protein YdhL.
Protein: IF3_METRJ
Sequence: MPAPQKDGPRANRDIRGVREVQLIDDTGQNRGVVPFFDALNLAEEVGLDLVEIAPNSVPPVCKLLDYGRFRFNEQKKQNEARKRQKTVEVKEIKLRPGIDKHDYDTKMKSVHRFFEEGDKVKVTLRFRGREMAHQDIGLRLLERVKSETAEIAKVESEPMLEGRQMIMILAPR
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASK_TAPIN
Sequence: LFDQKTIKYIPIHYVLNISPSQEPNYYQHRPVVPINNQQMPYRYYARPVAVRPHAQIPQWQVLPNIYPSTVVRHPYRRPSFIAIPPKKLQDKTVRPNINTIATVEPTLIPTTEPTVNNVVVPEASSEFIITSTPETTTIPVTSPVV
What is the function of this protein?
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_RHOPB
Sequence: MKRTYQPSKLVRKRRHGFRARLATVGGRKVLAARRARGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PIMT_PSESM
Sequence: MTSQRTRERLIQRLCEEGIANQRVLDVIRKTPRHLFVDEALAHRAYEDTALPIGHNQTISQPYMVARMSELLLAAGPLDKVMEIGTGSGYQTAVLSQLVERVFSVERIKGLQDRAKERLVELNLRNVVFRWGDGWEGWPALAPYNGIIVTAVATDVPQALLDQLAPGGRLVIPVGAGEVQQLMLIIREENGFSRHVLGAVRFVPLLNGPIA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_MYCA1
Sequence: MRVLAAMSGGVDSSVAAARMVDAGHDVVGVHLALSTAPGTLRTGSRGCCSKEDASDARRVADVLGIPFYVWDFAEKFQADVIDEFVSAYARGETPNPCVTCNQKIKFSALSAKAVALGFDAVATGHYARLSGGRLRRAVDKDKDQSYVLAVLSAEQLRHAAFPIGDTPKPQIREEAARRGLAVAEKPDSHDICFIPSGNTRAFLGERIGVRRGAVVNADGTVLAEHDGVHGFTIGQRKGLGIAGPGPDGRPRYVTAIDADTATVRVGEAADLDVREMLGRAVVFTSGTAPSGPFECAVQVRAHGETADAVAELVGDELVVRLRAPLRGVAPGQTLALYRHDPDGDEVLGSATIAGTSR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSIE_SALHS
Sequence: MMPLSRSRLEFIATILQNVLNLGLLTLGLILVVFLGKETVHLADALFAPEQASKYELVEGLVIYFLYFEFIALIVKYFKSGLHFPLRYFVYIGITAIVRLIIVDHKTPMDVLLYSAAILLLVITLWLCNSNRLRRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEF96_ARATH
Sequence: MGSLRLSTVAIAVVVCLSILLISPTEVDGRQVCDYDKGECNSYEKSSTCIEPCKQLDSKFIGGRCIPVGGITGMGLCVCCRDVQRGAEKESM
What are the official names of this protein?
Defensin-like protein 96.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: MVP_LEIIN
Sequence: MTDSVIRIKRYHYIHILDNNTNVTRTISGPVVYTRKEHETCLFDPCPCVSVPPRHYCVVKNPCVRGEAGEVVLESSGQVKLRLGDSEIRFEGEPFPLYPGEELDCRDGKGVQKLQLIPPNTGLHVRCVRDFKDADRRVGAGTEWMVAGPQTYIPRVEVVVVEEVKATVIYPNTALLVQANVNFTDRCGVPRVAGEKWLVRALGAYLKSVEETVLGLIQGTMLSDLKALRLSAVRSFTDVYGKARRAGEQWQVTLKDAPVHIVDAYETKVADVAAVSLSAKEYVIIHHPVDDTGHNRFGETLVRRGECTFFLQPGETMPRGVEQVLVVGKEEALLLEAVCEYRDGGEKRQPGSRWMVHGPLEYIPANEVKLLEHRRMMALDKNEGIYIMNTTTGEVRAVIGKPYMLDVNEVLWEKHLPLAVEELLESPNGSIQTSERNPGFVSHREKYRIVRFNVQHNAAVQIYDYRKKQPRIVLGPNLVMLAPHEEFTVLSLSGGTPKVPNSLQSLQLFLGPRFSSDTIVVETSDHARLRLRLSYNWYFDIDRANPSRRTFSVPDFIGDCCKTIASRVRGAVAAEDFDSFHRNSAKIIRTAVFGVDEAGETKKNLRFTANDFVVTNIDVQSSEPTDEKTRDSLQKSVQLAIEITTKSQEAAARHGNELKDQEAKGQLERQKLLDKIEVENARTKWLELQAKSEAVQASGQSVAEAKARAEALFIEVRSEMQQAEMRAKAYRISAEAELQKLQQRQALELEYTQRQNEIDVSKARAAAEAEAEKVKRMVDCIGRDTLVAIARAGPETQVKLLSSLGLKGYLITDGNSPVNLFGTAQGMIGEPKK
What is the function of this protein?
Required for normal vault structure.  Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction.  Vaults may also play a role in nucleo-cytoplasmic transport (By similarity).
What are the official names of this protein?
Major vault protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YP142_YEAST
Sequence: MFNRVLIQSTNLDVGWVQEDSNRSTEGLGWQIVSEGGSNDTRVTVSSGNLTPHNSNLRTPDFLGGSVDVGNTLTQVKLSILWSSDTFDLDQRDIWVVDSLGSLVG
What are the official names of this protein?
Putative uncharacterized protein YPL142C.
Protein: ACCD_SORC5
Sequence: MTWPEKTLPTTDASEKRSLGAGVFRRCDGCSHTHDAAELARTFEVCSQCGHHHKLDADGWRRLLLDDGELAAWDEHLVPNDPLRFSDGKSYRDRVAALHKKGRAKEAIEIGRGRLGGRDIAYGAFVFAFMGGSMGSVVGEKITRLFERATREELPVVLLQASGGARMQEGILSLMQMAKSVSALERYRKARLPFLSVLLHPTTGGVAASFAFLGDANIAEPKALIGFAGPRVIENTIRQTLPAGFQRSEFLLDHGMVDAIVPRPEMKAYIGTLLQHLTAGRRARR
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_BORBZ
Sequence: MICGIDEVGRGCIFGPILSAAVVFKKKPSFIKELDDSKKLKKEKREYLSSLILKNSYYAFAEISNITIEKINIHNASLLAMQTAYENLKLNCSLVLVDGKFVPKITAKNVKAIIKGDSIIDEIKAASIIAKVKRDKLMDEYDKIYPLYLLKKNKGYPTKEHKNAIKKYGVLSLHRKNFKLI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1836_MYCTO
Sequence: MGRHSKPDPEDSVDDLSDGHAAEQQHWEDISGSYDYPGVDQPDDGPLSSEGHYSAVGGYSASGSEDYPDIPPRPDWEPTGAEPIAAAPPPLFRFGHRGPGDWQAGHRSADGRRGVSIGVIVALVAVVVMVAGVILWRFFGDALSNRSHTAAARCVGGKDTVAVIADPSIADQVKESADSYNASAGPVGDRCVAVAVTSAGSDAVINGFIGKWPTELGGQPGLWIPSSSISAARLTGAAGSQAISDSRSLVISPVLLAVRPELQQALANQNWAALPGLQTNPNSLSGLDLPAWGSLRLAMPSSGNGDAAYLAGEAVAAASAPAGAPATAGIGAVRTLMGARPKLADDSLTAAMDTLLKPGDVATAPVHAVVTTEQQLFQRGQSLSDAENTLGSWLPPGPAAVADYPTVLLSGAWLSQEQTSAASAFARYLHKPEQLAKLARAGFRVSDVKPPSSPVTSFPALPSTLSVGDDSMRATLADTMVTASAGVAATIMLDQSMPNDEGGNSRLSNVVAALENRIKAMPPSSVVGLWTFDGREGRTEVPAGPLADPVNGQPRPAALTAALGKQYSSGGGAVSFTTLRLIYQEMLANYRVGQANSVLVITAGPHTDQTLDGPGLQDFIRKSADPAKPIAVNIIDFGADPDRATWEAVAQLSGGSYQNLETSASPDLATAVNIFLS
What are the official names of this protein?
Uncharacterized protein MT1884.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MLTF_ACTPJ
Sequence: MKGLIARFIAGFALLLWAWDMVFPWQQLMQAEENRYNQIQQRKILRVGMVNHPLSYFIGAEGTAGIEYELAKSFANYLDVRLDIKTFDNSEQLFSALKDNKVDIAAAGLLYQPELSKQFQIGSAYYSASWQVVYKKGSNRPYKLSELEGDLIIPAGSAVLPILQRLKEDNPKLSWQTTNQFTQEELLLQVAEGKIPYTVGISVDISAAQHIRPNIAVGFDLTDEAPVLWYLPNSSYSELQAAVLDFMNHANETGLISRIEEKYFNHLAHFDYVDIQSYLKAIKLVLPKYQSLFEKYRGDLEWQMLAAIAYQESHWDPNATSPTGVRGMMMLTRDTAERMKITDRTSAEQSIRAGSEYLHMLMRQIPETVPKEDRIWYGLAAYNMGFGHLLDVRRLTRQLGGNPDNWLDVKKNLPLLAEKRHYSGLKYGYARGFEAFQYVENIRRYYSSIINHQRVEEQQIQNNEEQPSVPQEISKESDSTLKE
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: TIM10_EMENI
Sequence: MSFLFGGAPKMSSEQKIAAAETEVEMITDMFNRLSESCSKKCIPNDYREGDLNKGESVCLDRCVGKFFEVNIKVSEKMQGVAGQQQGGAGLSL
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim10.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: PA2H1_LATCO
Sequence: NLIQFSQLIQCANKGKRPTLHYMDYGCYCGPGGSGTPVDDLDRCCKTNDDCYGQAEKKGCSPLSTNYNFDCFPGGPQCGKGTTCQRFVCDCDLKAALCFAKSPYNNKNFNIDTKKRCK
What are the official names of this protein?
Basic phospholipase A2 homolog 1, svPLA2 homolog, Phospholipase A2 homolog I, PLH-I.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLO_ACHLI
Sequence: MKDYTLIALAYNQEIRIYTSVSTNLVEKSRKLHKTLPTASAAMGRFLTASAMMSLMYKDGERLTLKIDGDGPIGQMTVEAKNGVVRSTILNPNVYLVYGEGPKMGKLNVGAAVGAGTLSVTKDWKENYFTSSSPLQTGEIGDDFTYYYATSEQTPSAVGLGVLVSRGKKVIQAGGFIIQVLPHASEKTLNQLESIISKINSVTDLLKSNHTPEDMINILSDNTGEILEKHELKYHCGCSRKKYFDALSRLNKQALEDILHEDGQAEVVCQYCNKKYIYTSEDLTKMIASK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YB2H_SCHPO
Sequence: MTTTPLGKMIQDGDFVFQKAKKGTTIPKARKKTLTKDLQVQVAKELEQESSSTFRFAYVFPRKAQNHYYSPSRTHTSSIKKKRPKLCSNINLTPWSLIDSTSNKSIREQSREMGIISIQKWAEQARMRSLCFPKN
What are the official names of this protein?
Uncharacterized protein C31F10.17c.
Protein: TAF10_HUMAN
Sequence: MSCSGSGADPEAAPASAASAPGPAPPVSAPAALPSSTAAENKASPAGTAGGPGAGAAAGGTGPLAARAGEPAERRGAAPVSAGGAAPPEGAISNGVYVLPSAANGDVKPVVSSTPLVDFLMQLEDYTPTIPDAVTGYYLNRAGFEASDPRIIRLISLAAQKFISDIANDALQHCKMKGTASGSSRSKSKDRKYTLTMEDLTPALSEYGINVKKPHYFT
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473).  TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473).  TAF10 is also component of the PCAF histone acetylase complex, the TATA-binding protein-free TAF complex (TFTC) and the STAGA transcription coactivator-HAT complex (PubMed:18206972, PubMed:11564863, PubMed:9885574, PubMed:10373431, PubMed:12601814).  May regulate cyclin E expression (By similarity).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 10, STAF28, Transcription initiation factor TFIID 30 kDa subunit, TAF(II)30, TAFII-30, TAFII30.
What is the protein family that this protein belongs to?
Belongs to the TAF10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOD_BRUSI
Sequence: MAETQVRNFNINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEAKTYLQAVPYLDRLDYVAPMNQEHAYALAVERLLDIEVPKRGQLIRVLYSEIGRILNHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERACGARMHAAYFRPGGVHQDLPDQLIEDIGKWIDPFFTTLKNLDDLITPNRIFKQRNVDIGVVKLEDAWAWGFSGVMVRGSGAAWDLRKSQPYECYSEMEFDIPVGKNGDCYDRYLIRMEEMRQSARIMRQCVDLLLGKERVGPVSNTDHKIVPPKRGEMKRSMEALIHHFKLYTEGYHVPAGEVYAAVEAPKGEFGVYLVSDGSNKPYRCKLRAPGFAHLQAMDFLCRGHMLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LDHA_NOTAN
Sequence: MSTKEKLISHVMKEEPVGSRNKVTVVGVGMVGMASAISILLKDLCDELAMVDVMEDKLKGEVMDLQHGSLFLKTKIVGDKDYSVTANSKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVAWKLSGFPRHRVIGSGTNLDSARFRHLIGEKLHLHPSSCHAWIVGEHGDSSVPVWSGVNVAGVSLQGLNPQMGTEGDGENWKAIHKEVVDGAYEVIKLKGYTSWAIGMSVADLVESIIKNMHKVHPVSTLVQGMHGVKDEVFLSVPCVLGNSGLTDVIHMTLKAEEEKQVQKSAETLWGVQKELTL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_CHLPM
Sequence: MKKTSLSSWHEKAGAKIIDFGGWLMPVQYSGIMAEHKAVRSAAGLFDVSHMGNFYVKGRRALEFLQSVTTNDLSRTVDGQAQYTIMLYENGGIVDDLIIYRIDSVTFFLIVNAGNCDKDFAWLEEHAGAFEGVQLSNHSDQLSLIALQGPKAFSILSRVIPEIDADRLPSFHFRQLPFMGAELMVARTGYTGEAGVEICLPNALAQPLWEALLDAGREDGLVPVGLGARDTLRLEMGYSLYGHEIDQDTNPLEARLKWVVSMEKGPFIGREACRQVELDPRFGVAGFSLEGRALARQGCRVFNADRQEIGKVCSGTISPTLQEPIGTASLVREYLKPGTPVFVEIRGSLQPGQIRRLPFVKPALL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: PCL_DROME
Sequence: MMNNHFHLQHDHPPQNVAHPFMQQPSTAVPSAPPATYGYLAQPAGQQPQWMTTTYQILPPSVGPATVAKRYYATTGPQTTHPTHPSTIQITNSFAQQSTPPKQQAATSCSPFKANNIRIISTAPSVYSLNKPPQEAHSTYAPVQSYYLPSGGGQTAGQINLLAASGTGKQLQPPPLVPVTNSTSPPSTVVLDRINICINNHYTETPTSLSSSLTTAQQPSPIIPAIQHKAILPLIDSSTADSSSCSSSSVSSSSYSGTATTSAAVVIVDEPDSTTTTPQTPPTTPEAMSSPGKSSPSPPLLATQSLLKGVNSMKPSFKTVEAAPPTPPTPPSPPPPPPAPPVAAPSPAVTYALQEDVFIKCNDGRFYLGTIIDQTSDQYLIRFDDQSEQWCEPDKLRKLGGGSSITAGGGGASTTESTNTSPSGPMCVACKRSDIEDVVEICERCGRGYHRGCTVEIVTGSGIWSCKRCAKPMKMQQPVSHKITKPAGICRQLPYHADKLSWDEKHRVNEEQIYCYCGKPGKFDHNMLQCCKCRNWFHTQCMQNFKKKLLRGDMFFVFCCTVCNNGIEFVRRMQIEWVDVLHIALYNLRKHQHQKYHHLLNDIWPFILEQRHQLPICEKWRTLPETALMERLKQTLKDYSDRFVCGREFKRAPAFYALRHSGPPHIPKVFLEPHEELSDELLEKRFKLMLMPEEPDEGANELPKRVPKDVYEFNTDEDDPVETSEDEIPIKQIIEKAKKQAAQKADKHDELPLKPDLADDNANDGDPGKLPAPIPPLLDANSSRKRKAFRLSKRYDNSRNHCDLSSDENSSSSRGTSSLDLIIPPPVNFLGRNNPFLMATPKKASQGRSISVGTGVGVNGIINSIFKLKGTSKEQPRMVRTIKRRLSAKDITIGPNQEVRRRRTRRLTTAIEVISTTTINPIPSHYLPIYAKDLQPPAPPMGKPTHGRLLRQRPQKQSPSQSRRNSTSSTATSSSSNGIGAPGHSMLDLKQSVNKYFGGAMNRIDAGEPFAIRAKRRMGNGQVQYLVEWGGDTATTAIGLLGN
What is the function of this protein?
Polycomb group (PcG) protein.  While PcG proteins are generally required to maintain the transcriptionally repressive state of homeotic genes throughout development, this protein is specifically required during the first 6 hours of embryogenesis to establish the repressed state.  Component of the Esc/E(z) complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3, leading to transcriptional repression of the affected target gene.  The Esc/E(z) complex is necessary but not sufficient for the repression of homeotic target genes, suggesting that the recruitment of the distinct PRC1 complex is also required.  Required for the correct spatial expression of the homeotic genes of the Antennapedia and Bithorax complexes.
What are the official names of this protein?
Polycomb protein Pcl, Polycomblike protein.
What is the protein family that this protein belongs to?
Belongs to the Polycomblike family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with chromatin. Colocalizes with many PcG sites on polytene chromosomes. It also associates with many unique sites on polytene chromosomes.