PharMolix/UniProtQA huggingface dataset:
Protein: COX1_MYCLE
Sequence: MTAEALSSGELKAIRPYPARTGPKGNLVYKLITTTDHKMIGIMYCVACFIFFFVGGLLALLMRTELAAPGLQFLSNEQFNQLFTMHGTIMLLFYATPIVFGFANLVLPLQIGAPDVAFPRLNAFSFWLFLFGAAIGMAGFITPGGAADFGWTAYTPLTDAIHSPGVGGDLWIMGLIVAGLGTILGAVNMITTVVCLRAPGMTMFRMPIFTWNILVTSILVLIAFPLLTAALFGLAADRHLGAHIYDAANGGVLLWQHLFWFFGHPEVYIIALPFFGIVSEIFPVFSRKPIFGYTTLVYATLSIAALSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWVGTMWKGQLTFETPMLFSVGFAVTFLLGGLTGVLLASPPLDFHVTDSYFVVAHFHYVLFGTIVFSTFAGIYFWFPKMTGRLLDEQLGKLHFWLTFIGFHTTFLVQHWLGDMGMPRRYADYLPTDGFQGLNVVSTIGSFILGASMFPFVWNVFKSWRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFTELPRIRSERPAFELHYPHMVERLRDEAYVGRRHAEELVEVSLH
What is the function of this protein?
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Subunits 1-3 form the functional core of the enzyme complex.  CO I is the catalytic subunit of the enzyme.  Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).
What are the official names of this protein?
Probable cytochrome c oxidase subunit 1, Cytochrome aa3 subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCF_COTJA
Sequence: MKKAQTWIITCFCLQLLLLNPLVKTQSSCGNPVTDDVNDIAKLVGNLPNDYLITLKYVPKMDSLPNHCWLHLMVPEFSRSLHNLLQKFVDISDMSDVLSNYSIINNLTRIINDLMACLAFDKNKDFIKENGHLYEEDRFIPENFFRLFNRTIEVYKEFADSLDKNDCIMPSTVETPENDSRVAVTKTISFPPVAASSLRNDSIGSNTSSNSNKEALGFISSSSLQGISIALTSLLSLLIGFILGVIYWKKTHPKSRPESNETTQCHGCQEENEISMLQQKEKEHLQV
What is the function of this protein?
Ligand for the receptor-type protein-tyrosine kinase KIT.  Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.  KITLG/SCF binding can activate several signaling pathways.  Acts synergistically with other cytokines, probably interleukins (By similarity).
What are the official names of this protein?
Kit ligand, Mast cell growth factor, MGF, Stem cell factor, SCF, c-Kit ligand.
What is the protein family that this protein belongs to?
Belongs to the SCF family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type I membrane protein. Secreted. Note=Also exists as a secreted soluble form (isoform 1 only). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium. Cell projection, filopodium.
Protein: NUOH_RHILO
Sequence: MDTFFSFYVLPALLILLKSVVLIVVLLIFVAYILYADRKIWAAVQLRRGPNVVGPWGTLQAFADLLKFVFKEPVIPSGANKGVFLLAPLVSAVLAISAWAVIPVNQGWAIANVNVGILYVFAISSLEVYGVIMGGWASNSKYPFLGALRSAAQMVSYEVSIGFVIVTVLLTAGSLNLSDIVLSQHDGIGTRLGLPNTFLDWNWLALFPMFIIFFISALAETNRPPFDLVEAESELVAGHMVEYSSTPFLLFFLGEYVAIVLMCALATILFLGGWLPPFDFVPFTWVPGVIWFVLKVCFVFFGISMVKAFVPRYRYDQLMRLGWKVFLPISLFMVVATAAFLKITGFA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LUXR_ALIFS
Sequence: MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
What is the function of this protein?
Transcriptional activator of the bioluminescence operon.  Binds to the OHHL autoinducer.
What are the official names of this protein?
Transcriptional activator protein LuxR.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-regulated transcriptional regulatory protein family.
Protein: TMCAL_ALKOO
Sequence: MKILGLVTEYNPFHNGHRYHLEQSKEITKATHTVAVMSGNFLQRGEPAMVHKWERAKMAVKSGVDLIIELPTSYACATAELFAYGAITLLHRLGSVDCLCFGSEIGNVSPLLQIAEVLSTPTSRFQEVLREHVNLGGTFPVARSMALLKYLEETKEYDVASLREISDALKSPNNILGIEYLKSLKKLNSPIVPYTISRKSADYHSKDITDSSIASATAIREHLLKENHLKGIASVVPKDTLDILAHSVGIGMAPIFATDFQQILLALLRRSTPENLKNIFDVEEGLENRIYHCAHQASTLNELYEAIKSKRYTRTRIQRILMHLLLNITKKDIFYFNDHGGPQYARILAFNDKGREILQSFKSTSSIPMVSNLKNYTPQNSAADRMLAIDIRATNLYTLAFTDEKRGGALMDYRTSPFYENSKD
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CU03_CONVR
Sequence: NTESTKGESLLGK
What are the official names of this protein?
Conopeptide Vi003.
Protein: OMP7_STAAU
Sequence: AAKPLDKSSSSLHHGYSKVHVP
What is the function of this protein?
Binds various plasma and ECM-proteins.
What are the official names of this protein?
65 kDa membrane protein, map-ND2C.
What are the subcellular locations of this protein?
Cell membrane.
Protein: ACHA5_MOUSE
Sequence: MAARGSRRRALRLLLMVQLLAGRWRPAGAARGARGGLPELSSAAKHEDSLFRDLFEDYEKWVRPVEHLSDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKIIRVPSDSLWIPDIVLFDNADGRFEGASTKTVVRYNGTVTWTQPANYKSSCTIDVTFFPFDLQNCSMKFGSWTYDGSQVDIILEDQDVDRTDFFDNGEWEIMSAMGSKGNRTDSCCWYPCITYSFVIKRLPLFYTLFLIIPCIGLSFLTVVVFYLPSNEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPWVRKIFLHKLPKLLCMRSHADRYFTQREEAEKDGGPKSRNTLEAALDCIRYITRHVVKENDVREVVEDWKFIAQVLDRMFLWTFLLVSIIGTLGLFVPVIYKWANIIVPVHIGNTIK
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-5.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: SHSA2_BOVIN
Sequence: MWAGCHPDAASLLRLLLAALLAAGALASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSADARLDQGGCDNDRQQGAGEPGRADKDGPDGSAVPIYVPFLIVGSVFVAFIVLGSLVAACCCRCLRPKQEPQLSRAPGGPRLVETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHPPFVGYTVQPDSVPLTPVPPFLDGLQTGYRQLQAPFPHTNSEQKMYPAVTV
What is the function of this protein?
Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling.
What are the official names of this protein?
Protein shisa-2 homolog, Transmembrane protein 46.
What is the protein family that this protein belongs to?
Belongs to the shisa family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RL17_CLOBA
Sequence: MAGYRKLGLPTDQRRAMLRNLVTSLLKHGKIETTVTRAKETRSIAEKMITLGKRGDLHARRQALAFIQEELVVKNLFDNVAPKYAERNGGYTRMYKKGPRRGDGAEVVILELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MINC_PROMA
Sequence: MSLNNLNKKENFISIQLLSENWAEELRLSIKGYQKGFIKINSGALPLTCKDINELKRICNGVGMEIISIESTNAESIVSASALGLNANLKLKDNVFTEVKSDFKDLSESKVNAALLFHKGTLRSGEVLEADEDILILGDVNPGATVLAGGNVMIWGRLLGIAHAGKYGNNQAKITALQLRPVQLRIANKIARGPKEKPELGLAEEATIQEEVIVIKPARTT
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: CRJ32_CRYJA
Sequence: MARAMHTVWIALVPTLFVFLQGINVKAATFDITNQCPYTVWAAASPGGGRQLAKGQTWTIQVPAGTTGGRVWARTGCSFDRSGRGTCQTGDCNGMLSCQGYGQVPATLAEYALNQYMNLDFYDISLVDGFNVPISMTPTSTNPNCKGRITCLSDINSKCPSELKVNGGCKSACARYNTAQYCCTGASANNCGPTNYSKFFKGQCPQAYSYAKDDATSTFTCPSGTNYKVVFCG
What is the function of this protein?
May be involved in disease resistance.
What are the official names of this protein?
Pathogenesis-related thaumatin-like protein 3.2.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
Protein: UBX11_HUMAN
Sequence: MSSPLASLSKTRKVPLPSEPMNPGRRGIRIYGDEDEVDMLSDGCGSEEKISVPSCYGGIGAPVSRQVPASHDSELMAFMTRKLWDLEQQVKAQTDEILSKDQKIAALEDLVQTLRPHPAEATLQRQEELETMCVQLQRQVREMERFLSDYGLQWVGEPMDQEDSESKTVSEHGERDWMTAKKFWKPGDSLAPPEVDFDRLLASLQDLSELVVEGDTQVTPVPGGARLRTLEPIPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNGVPFKVSDLRNQVYLEDGLDPFPGEGRVVGRQLMHKALDRVEEHPGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGPCPGPGPGPSPGPGPGPSPGPGPGPSPCPGPSPSPQ
What is the function of this protein?
May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 and RND3.  Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity).
What are the official names of this protein?
UBX domain-containing protein 11, Colorectal tumor-associated antigen COA-1, Socius, UBX domain-containing protein 5.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL25_SHEAM
Sequence: MSYTIPAQTRTEIGKGSSRRLRREGKVPAVIYGVGKEPVSIVFDHKDIINIQANDDFYTSVLTIVLDGKEVNVRAQAMQRHVFKPMIDHVDFVYA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: RL2_THET2
Sequence: MAVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SYR_HALSA
Sequence: MLYNLRQELLAGIRAATSDAGYDYEVDQSAIELEDITDEEKGEFSSPISFSIAAAAGAPPVDVAAAIADAHRSNGLPAEVEAVTVEGGHINYHADTTDLADATLSTILRDGSEYGTRTDADPDTILADVSSPNIAKPLHVGHLRNTILSDAVMNILEARGHDVTRDNHLGDWGVQFGNLMHEYTEFGDEATLEDDAIEHLLDLYQQFEQRDSMLADLEDDETVTDQFADAVTEERDYHADSGKEWFTRLEQGDEDATALWERFRTVSIDRFKQTYDDLDVAFDVWNGESFYAQEGWNDVIIEKAIENDVAMRGEGESVYIPVYPDDYENVGDPQAADVDASLDRARQMREANDDLEDADFDPFYIVKSDGSTLYGTRDLATIEYRIEEYDADQSVYVVANEQNQYFQQLFVAARKMGYNDIKLKHIDYGLISLPEGSMSTRKGQIITAREVLDRAQDRAEEIIAEKGRIDDAEAQSVATKIALATIKYEMVAAKRERDTTFDIDESVALEGDTGPYVQYAATRGYSILDGADAAPEIDDLDPSVFNDTDVELLFELARYPLVLERCEERYDAAPLAHYLLQLAHVFNSFYHKNAVLDAENARTERLLLTKATTQIFDNGLGLLGIDVLEEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALC_SALSA
Sequence: MIYKLYFAIALCFSLCFDLCIAESYVLDDKVGLGRTFDGIGGLSGGGATSRLLVNYAEPYRSQILDYLFKPNFGASLHILKVEIGGDAQTTDGTEPSHMHYENDENFFRGYEWWLMREAKKRNPNITLIGLPWAFPGWVGHGKNWPYDFPDITASYVVSWILGAKHYHDLNIDYVGIWNERNFDSKYIKLLRYTLDKSGLERVRIIASDNLWQPITYSLCVDQELADAVDVIGAHYPGTTTVIEALKTQKKLWSSEDYSTFNDEVGGGCWARILNQNYVNGLMTATISWNLVASYYEDLPFGRDGLMTAEEPWTGNYVVESPIWITAHTTQFSQPGWTYLQTVGHLVHGGSYVALTDSNGNLTVVIETMTHDHSVCIRPPLLPFNVTAQNVTFQLKGSFALIKELQVWQSRFDFKTKKPFFFKKLSPLKISDGSFTLSLDVDEVYTLTTISTGLKGTYPDPPTSGPFPKVYFDDFNVANPSFSEAPDFADQTGVFEYYINLTDPGPHVFTLRQVVTQMPVTWATDADQTISVIGDYKWQNLTVTCDVFMETVKTGGVFIAARVDKGGQSVRSAKGVFFWVFADGSYKVTNDLVGKTVLAEGLSGTRAYGWHTLTLTVEGQYATGLLNGYPLWKDAVVLGPKNGWAAIGTHSFELAQFDNFAVEAKL
What is the function of this protein?
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine.
What are the official names of this protein?
Galactocerebrosidase, GALCERase, Galactosylceramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 59 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: EMC10_XENTR
Sequence: MAAGCLVGQRAGPLSDKLSGYCWVLLPLLLVATAQASVCRLKTGDGRDSESCGTNLELEHSFELDDSIHFKKRGSLIWSGTAEQSISILQKQLTEDERNKLRDIANLNGLYRIRVPRKLGITEEANEYVTSFVRACSMVESHLSDQISVHTDISGNVVGISIVTFPGSCNGAEVEDVDLEMFNTTVYIQQPIAAAVPETAAFIERLEMEQAQKAKNPQEQKSFFAKYWMYIIPVVLFLMMSGASDAGNQGGNGGGGGGSGGGR
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.  Promotes angiogenesis and tissue repair in the heart after myocardial infarction.  Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways.
What are the official names of this protein?
ER membrane protein complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the EMC10 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: TRUB_ROSDO
Sequence: MGRRRKGRDISGWLIVDKPAGLTSTAVVNKVRWALDAKKAGHAGTLDPDATGVLAVALGEATKTVPYVTGALKAYEFEIRLGQATNTDDAEGEVIAQSDLRPTEDEIKEALSAFIGDIEQVPPQFSAVKVDGERAYKRARDGEEMTLAARPLYVDSLLLIDRPDADHVLLEMVCGKGGYVRSIARDLGAALGCLAHVRSLRRIWSGPFDAKNAADLETIEALARTPELDAHVQPLETALDDMPEVKATAEGAVRLRNGNPGMVLASGIEYGETCWASFESRAIAIGRYKSGELHPVRVINAPD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: HOA_THERP
Sequence: MKTLTPPRVTDTTLRDGSHAMRHQFTREQVRAIVAALDEAGVPVIEVTHGDGLAGSSIQYGFSATSELELIEEAAKTAKRAKIAALLLPGIGTRRELSAAIERGIKVVRIATQCTEADISEQHFGMAKEMGLETVGFLMMAHMRPPEFLAEQAALMESYGADCVYIVDSAGAMLPDDVRRRVAALKERLSIQVGFHAHNNLGLAIGNTLAAIEEGADQVDGCLRGLGAGAGNAPTELIAAVLDKLGINPGLDVFKLMDAAEYIVAPIMPYQPIPDRDAITIGYAGVYSTFLLHARHIAAEFGLDPREILVELGRRQAVAGQEDWILDVALDILRRKRAAEGAGDAREPAAAERSAD
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: HUTH_BACCZ
Sequence: MITLTGHTLTVEEMKRLLLEGEGVTACPNSMQKVAECREVVEKIVEDGKVVYGITTGFGKFSDVLIQKEDVKALQHNLIQSHACGIGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNMLLEFVNRKIHPVVPQQGSLGASGDLAPLSHLALVLLGEGEVFYKGKRAHAMVALTEEGLEPIELEAKEGLALINGTQAMTAQGVLSYIEAEATAYQAELIASMTIEGLQGIIDAFDENVHKARGYKEQVEVASRIRDILHDSKLTTKQGELRVQDAYSLRCIPQVHGASWQVLNYVKEKLEIEMNAATDNPLIFDGGEKVISGGNFHGQPIAFAMDFLKVGMAELANISERRIERLVNPQLNDLPPFLSPEPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIASRHAHQIIQNVRRVLSIEMICAMQAAEYRGIENMSTVTKSFYHQGRQQVPSITNDRIFSTDIENITHWLKTNYSIKERLDVNAAL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLP1_SCHPO
Sequence: MEIAGNSSTISPTFSTPTKKRNLVFPNSPITPLHQQALLGRNGRSSKRCSPKSSFIRNSPKIDVVNTDWSIPLCGSPRNKSRPASRSDRFIPSRPNTANAFVNSISSDVPFDYSESVAEACGFDLNTRVLAFKLDAPEAKKPVDLRTQHNRPQRPVVTPAKRRFNTTPERVLDAPGIIDDYYLNLLDWSNLNVVAVALERNVYVWNADSGSVSALAETDESTYVASVKWSHDGSFLSVGLGNGLVDIYDVESQTKLRTMAGHQARVGCLSWNRHVLSSGSRSGAIHHHDVRIANHQIGTLQGHSSEVCGLAWRSDGLQLASGGNDNVVQIWDARSSIPKFTKTNHNAAVKAVAWCPWQSNLLATGGGTMDKQIHFWNAATGARVNTVDAGSQVTSLIWSPHSKEIMSTHGFPDNNLSIWSYSSSGLTKQVDIPAHDTRVLYSALSPDGRILSTAASDENLKFWRVYDGDHVKRPIPITKTPSSSITIR
What is the function of this protein?
Required for mad2-dependent spindle checkpoint activation.  Promotes ubiquitin-dependent degradation of cdc13 by the anaphase promoting complex/cyclosome (APC/C).
What are the official names of this protein?
WD repeat-containing protein slp1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CDC20/Fizzy family.
Protein: RLMH_STAAW
Sequence: MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVTDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_ALISL
Sequence: MSEMTPREIVHELDSHIIGQDKAKRSVAIALRNRWRRMQLQPELRAEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDVAIKMTHQQAVEKVKFRAEEQAEDRILDILLPPARDAWGKNEEGDNDSGTRQSFRKKLREGKLDDKEIDVDVAAPQVGVEIMAPPGMEEMTNQLQGMFQNLSGGETTKKRKMKIKDALKALAEEEGAKLVNPEELKEQAIFNVENHGIVFIDEIDKICKGSNSQSGDVSREGVQRDLLPLVEGSTVSTKHGMVRTDHMLFITSGAFQMAKPSDLIPELQGRLPIRVELEALTANDFKRILTEPNASLTEQYIALLATENVNIEFTEDGISRIAESAFRVNETTENIGARRLHTVMERLMEEISYDASEKGGDSLTVDDAYVTSRLGELIENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASL1_CANSA
Sequence: MKCSTFCFWYVCKIIFFFLSFNIQISIANPQENFLKCFSQYIPTNVTNAKLVYTQHDQFYMSILNSTIQNLRFTSDTTPKPLVIITPLNVSHIQGTILCSKKVGLQIRTRSGGHDAEGMSYISQVPFVIVDLRNMHSVKIDVHSQTAWVEAGATLGEVYYWINENNENLSFPAGYCPTVGAGGHFSGGGYGALMRNYGLAADNIIDAHLVNVDGKVLDRKSMGEDLFWAIRGGGGENFGIIAAWKIRLVAVPSMSTIFSVKKNMEIHELVKLVNKWQNIAYMYEKELLLFTHFITRNITDNQGKNKTTIHSYFSSIFHGGVDSLVDLMNKSFPELGIKKTDCKQLSWIDTIIFYSGVVNYNTTYFKKEILLDRSGGRKAAFSIKLDYVKKPIPETAMVTILEKLYEEDVGVGMFVFYPYGGIMDEISESAIPFPHRAGIMYEIWYIASWEKQEDNEKHINWIRNVYNFTTPYVSQNPRMAYLNYRDLDLGKTNFESPNNYTQARIWGEKYFGKNFNRLVKVKTKVDPDNFFRNEQSIPPLPLRHH
What is the function of this protein?
Has no cannabidiolic acid synthase activity.
What are the official names of this protein?
Cannabidiolic acid synthase-like 1.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYS_MARMM
Sequence: MHDIKLIRDNPDAFDAGLAMRGLPAQSATLIELDASRREALGKQQDAETERNALSKQIGKAKASGDEAEFNRLRSEVDRLKAVLEESGQQARHFDEVLNQHLAALPNLPHADVPQGADEADNVEERRWGEPRTMAFTPRDHVDLGESLGQMDFKKAAEISGSRFVALRGGLARLERALAQFMLDLHTTEHGYEEVSPPYMVRDEAVFGTGQLPKFAEDLFRTTDDHWLIPTAEVPLTNLARETIHAEADLPMRMTAYTPCFRSEAGSAGRDTRGMIRLHQFQKVEMVSIVTPDESDAELERMTGCAEKVLQLLELPYRVMKLCTGDMGFAARRTYDLEVWMPSQDCYREISSCSTCGDFQARRMDARFRKEGEKRPAFLHTLNGSGVAVGRALVAVLENHQNEDGSITIPAALRPYMGGVERIEG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OST1B_ORYSJ
Sequence: MAPSLSTAVSSLLLLLLLAAAISVSSSPPMPEDSIRVISAEKRIDLTSPIVKVFLTLKLENDATAPEASQVLLAFTPTEVEHLAIVKATRAEGKRKKKIYVPLSVKASDLAAAPNGARLYSILLSTPLKPAEVTTLEVFYALTHSLEPFPAEITQSDPQLVYYRDSAVLLSPYHVLEQVTYIKMPSNRVESFTRVDPTSRAGNEVKYGAYNNQLPNSYVPILVHYENNRPFAVVEEFVRKVEISHWGNVQITEQYKLKHGGAQHKGVFSRLEYQSRPSISGVSSFKNLLARLPPRVHSVYYRDEIGNISSSHLRSDSHKSELEIEPRYPLFGGWHCTFTIGYGLPLQDFLFESDDGRRYINLTFGCPLLDTVVDDLTIKVVLPEGSTSPQAVVPFLMEQYLETSYSYLDVVGRTTVVLKKRNVVGEHNVPFQVYYEFNPIFMLAEPLMLISAVFLFFVACIAYLHMDLSIGKS
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1B, Ribophorin IB, RPN-IB, Ribophorin-1B.
What is the protein family that this protein belongs to?
Belongs to the OST1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.