PharMolix/UniProtQA huggingface dataset:
Protein: GAST_MOUSE
Sequence: MPRLCVYMLVLVLALATFSEASWKPRSQLQDASSGPGTNEDLEQRQFNKLGSASHHRRQLGPQGPQHFIADLSKKQRPRMEEEEEAYGWMDFGRRSAEEDQ
What is the function of this protein?
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes.  It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
What are the official names of this protein?
Gastrin.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SECB_ECOK1
Sequence: MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASTQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAD50_SULAC
Sequence: MIIREIRLQNFLSHEDTTVKFEGSINVIIGNNGAGKSSIIDGILFGLFKRTNRDIGKNEELIKKGKKSGQVSIKFEINGDTYLIDRNVGETSRDTISLLKEGKIITLARQSTTVNNKIKEILGFDHKILMSTTIIGQGSVESVFSDFPEVMKELLKINKLEMLRESNGPIHSLIKVLTDRIRSLQSIKDILKREEAEIDRLKKEIEEIKVKLENIEREAKEKEDELNQYNTEFNRIKEIKVQYDILSGELSVVNKKIEEIALRLKDFEEKEKRYNKIETEVKELDENREKINTISSFKSILVQIDSLKSQINVVENDLKRKKEKLKRKKELEEKEKQYEEIEKRKKELEEKEKQYEEIEKRLTYVLKNIERQKNEIEKLNYVDTQDLENKIKDVSDRINQIDNELKGLLDRRGDLNGRKEQTLKIYNNLNSIEDDRCPICGRPLDSEHKAKIREEIKVQLLELNKQITALQARINSLIKEREELEATRNKLQLELQKRSKEKGIYEAKLKELQRLEEEKNKLQNEILSLLSYHQEFENIAEKEKELIDYHEEYLKNSDILEEDIQEQEQRLNELNSKLSELEKSYNDYKAKYQFLPADLKSLVSLEERIRRRISELEKLKIEYERLKEEITRMKGLKEEYEKLKEEEDALLNRISELGYSEKRYKQLEEIIDKLSKILSGIEADKGKIKGSLEEKIKNIEEKERNIEELRNKMNEESKLNLGISKLQKLREVLDNKHLQSHIMNIVRNQIENNVNEVIAKFDLSFSAVEIDFVGKSELYVYTASGQKIHINALSGGERISIALALRLAIAKALMNQFSTLILDEPTVNLDEYRRKELIDVIRSAIEIVPQIILVTHDQELIQAGDYIIRVEKKGDTSKVEVSSYDR
What is the function of this protein?
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair.  The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA.  Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
What are the official names of this protein?
DNA double-strand break repair Rad50 ATPase.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
Protein: RL19_CLOAB
Sequence: MLDVIKEIEAEQIRTDLPSFNVGDTVRIEVRIKEGEKERLQAFEGTVIKRQNGGLRETFTVRRVAYGVGVERTFPLNAPVIAGLKVVRRGKVRRAKLYYLRDRVGKAAKVKEIR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL32_CANGA
Sequence: MAASLPHPKIVKKHTKKFKRHHSDRYHRVSENWRKQKGIDSVVRRRFRGNISEPTIGYGSNKKTKFMSPSGHKVVLVSNLKDLETLTMHTKSYAAEIAHNVSSKNRVTLLARAKALGVKVTNAKGRLALEA
What are the official names of this protein?
60S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: RL35_BIFAA
Sequence: MPKMKTNSAASKRVRVTGSGKLMHAGSAMRHNLEHKSARKRRELKADGVLATSQSKNMKKLLGR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ASTB_NOVAD
Sequence: MPLVEINFDGLVGPSHNYAGLSLGNLASASNAGEVSYPRAAALQGLGKMRHNLALGLTQGLFAPLPRPNPVFLGALGLNAIDEVDQAQRRLRAAAWSASSMWTANAATVSPAPDTPDGRCHLTAANLVTMPHRSQEWPDTVRQLRLAFADAAHFAVHDAVPACFGDEGAANHMRMCKSHDAPGIEIFVYGTTGGAFPARQHEQASRAVARLHGLAPERCLFVEQAPEAIAAGAFHNDVVAVANERVLFTHEQAFANPEATYAAIRERLPEAEIVVVPSSVVSLADAIRSYLFNAQLLTLPSGEMGLVIPVEAWETPSVRGWLEAHLASNGPIRRVLPVDVRQSMANGGGPACLRLRVVADPATVDPRFLLDEARVAIVEEVVRRHWPEQIDPADLGSDILAQTVHGARGALLAALELSELA
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: NUON_YERPB
Sequence: MTITPQQLIAMLPLLIVGLTVVVVMLSIAWRRDHFINATLTVIGLNLALLSLYFVGQVGPMDVTPLMRVDGYSMFYTGLVIIASLATSTFAYPWLVGYPDNREEFYLLVLIAALGGILLASANHLASLFLGIELLTLPLFGLIGYAYRQKRSLEASIKYMLLSAAASSFLLFGMALLYAESGSLSFVGLGQSLSDSMVHQPLILAGLGMMIVGLGFKLSLVPFQLWTPDVYQGAPAPVSTFLATASKIAIFAVVMRLFMYAPAADSEAVRLVLSIIAVASILFGNLMAISQTNIKRLLGYSSIAHLGYLLIALVAVQTHELALPLETIGVYLAGYLFSSLGAFGVVSLMSSPYKGPDAESLFSYRGLFWHKPILSAVMTVMMLSLAGIPMTLGFIGKFFVVAMGVSANLWWLTGAVVLGSAIGLYYYLRVTVSLFLSPPQSLVRDTPSNWALTAGGVVVLISAILVLVLGIYPQPLITLVQMAQPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KATG_SALRD
Sequence: MHNGSNGSVEQRDSMPETSREWWPGSLDVEILDQNAQDVGPWNGDFDYAEAFQELDYEALKEDIEEVMTTSKDWWPADYGHYGPLFIRMSWHAAGTYRTTDGRGGSSGGRQRLAPLNSWPDNANLDKARRLLWPVKQKYGRKISWADLLVLAGNVAMESMGFETFGFAGGREDDFKPDESIDWGPEDEMETWGRFNEEDELDNPLGATVMGLIYVNPEGPESTPDPEWSAQRIRKSFGRMAMNDRETAALIAGGHTFGKVHGADTDEHLQAEPEAAPIEQQGLGWHNEHGSGKGGDTITSGIEGPWTDAPTEWDMGYLDFLLDYEWEVHKGPGGAWQWRPKSDELKGVVPDAHDASETVDPMMLTTDVALKRDPDYREIIEDFRENPDAFEDAFARAWFKLLHRDMGPKERYLGPEVPEEDLIWQDPVPDADHDLIGDEEIAELKEAILETDLSVSRLVKTAWASASTYRDSDKRGGANGARIRLEPHRNWEANEPPQLAHALEVLTGIQKNFNDARTDDVRVSLADLIVLGGSAAIEKAAADAGHDVEVPFTPGRTDATQEQTDVEAFEYLEPKADGFRNYIADDPWQDWTPEEFLVDKADLLNLTPAETTVLVGGMRALDATHEQADGYGVFTDRPETLNNDYFVNLLDMGHEWDPVSEDKQHFKIRDRDTGEVKWKATRVDLIFGSNSRFRALSQVYGSGDAEEKFVDDFVDAWTKVMNLDRFDLE
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: ARI15_ARATH
Sequence: MEKLMTESGLKPVVIDSNQDLSRVYCGICSNIGDDDYDGDAVVVDGDLISTPFCSHKFCKACWSKYLKKNFFSVEKNHTAISCPDRDCRAAVGPETVEKLTVRDQAMYELYILKSYREKYLGWKLKLCPARGCNYVIEFHLASEDEEHSLNIVCLCGHIFCWRCMLESHRPVTCNNASDWLSRDLEKLIEEVDKPSTVSWIDANTKPCPHCFIPVEIDGERPWAQFLTCVCSGRFCWKCFRSPETHGTSGSCLAPARSSNVGFNHWNRAKPGISCLDLWNASQVNLVNAKYELEAFEESIIKKPSDLKEQDVKVLREGLMLIVQCRQFLKWSCAYDYIHTEYDMAKREYLRFLQQNASGIVHSFSQSIKEETEAKELTCGKLLSETTNIGNFFYHFIKTLREGLPEVQAESYDNYGGPYWLCDRCTYGNSWFQRACKMCCDPTASKMDELSD
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase ARI15, ARIADNE-like protein ARI15, Protein ariadne homolog 15, RING-type E3 ubiquitin transferase ARI15.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
Protein: GLMM_BORPD
Sequence: MTQRKYFGTDGVRGEVGGEVINAAFALRLGYAAGRVLARQHGGRGGSRPQVVIGKDTRISGYMLESALEAGLSAAGIDVLLAGPVPTPAVAYLTRALRLVAGIVISASHNPYQDNGIKFFSAQGMKLPDEVEAEIEAALHEPLGCVGSEALGRARRMQDSQGRYIEFCKSTFPNDLDLNGVKIVVDAAHGAAYNVAPHVFRELGADVHAIGVSPDGFNINEGVGALHPESLARAVRERGAHLGIALDGDADRLQMVDGDGRIYNGDELLYAIVRERMSRGTVAGVVGTLMTNYGFELEMQRLGVGFERAKVGDRYVMEQMQARGWLYGGESSGHLICLDCHTTGDGIIAALQVLTALRRGNVPLADWLGDLRMYPQKMINVPLAPGTDWKSHAGLAAATRAVEAELAGRGRVLIRASGTEPKLRLMVEAEEPALAASCAEKLAASLA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL32_BURP6
Sequence: MAVQQNKKSPSKRGMHRSHDFLTTSPLAVEPSTGEVHLRHHISPNGYYRGKKVVKTKND
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RL25_CORGB
Sequence: MAKYQTIEAAVRSEFGKGSARRARVAGQIPAVVYGADVESNLHVTVDHRTFAALVRQEGVNAVLELDIEGQKHLTMIKHIDQNVLTFNIDHLDLLAIKRGEKVEVDVPVIVEGEPAPGTMWVQDADTIKVEADVLSIPEEFKVSIEGLEFGAQVTAADIELDGDTTLVEDPETLIVNIVYPEVEAEETEDDEAASEGEEAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: NRDR_CLAMS
Sequence: MFCPFCRHPDSRVVDSRTSDDGLSIRRRRQCPECGRRFSTTETASLSVIKRNGVVEPFSREKIVTGVRKACQGRPVTDTDLAVLAQRVEEAIRATGASQIEANDIGLSILPPLRELDEVAYLRFASVYQGFDSLDDFEAAIAQLRVAHAATPDADAL
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: IMAND_ENTCS
Sequence: MTPTIITDVKAFAIKPDRHNLVVVKVETNKGVSGLGCATFQFRPLAVKTVVDEYLRPLLLGRDANQIEDLWQVMNVNSYWRNGPITNNAISGVDMALWDIKGQLADMPLYQLLGGKARTAIPAYTHAVADNLEDLYQEIDRFLAEGYRYIRCQLGFYGGNPSQLQTPDQPIAGSYFDQTDYMDTTLKMFAAIQERYGNQFQMLHDVHERLHPNQAIQFAKAAEPFNLFFLEDILPPDQNKWLQQLRSQSATPIATGELFNNPMEWQELVKNQQIDFMRAHVSQIGGITPALKLAHFCDAMGIRIAWHTPSDISPVGLAVNNHLNIHLHNAAIQETIAIPANTQSVFGGSPQPENGYFYPIEKSGIGITFDEAAAAEFPVVYRPHEWTQSRTPDGTLITP
What is the function of this protein?
Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding.  May have evolved a divergent function.
What are the official names of this protein?
D-galactonate dehydratase family member ECAG_02205.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: ILVC_CAMC5
Sequence: MAVNIYYDKDCDLSLIQSKKVAIVGFGSQGHAHAENLRDSGVKVVIGLAKGGKSWAKAEAKGFDVKIVSEATKDADVVMILTPDELQSEIYKKEIEPNLKDGAAIAFGHGFNVHFGQIKAPKNIDVIMIAPKAPGHTVRSEFVRGGGIPDLIAVEQDASGQAKQIALSYASAIGGGRTGIIETTFKDETETDLFGEQAVLCGGLCALVNAGFETLVEAGYEPEMAYFECLHELKLIVDLMYQGGMADMRYSISNTAEYGDYVSGGRVVGEESKRAMKEVLKEIQNGKFAKDFILERKAGYVRMNAERSIAERSLLNQTGKKLRAMMPWISAGKLVDQNKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: NOTR_ASPSM
Sequence: MPGIAMDGLSKLEAESERLTATIKSYVRHRRDVESSDQLRASPDANMEASRTKSVILASIANIKALLGGPVELLQDLARQVEIVACLRWLAEYQILACIPAEGGMSIQDLADLAGVPDIQLRRVIRLVGTSGFLQEPMPNYVSHTPLSAQFVTNQSWLDAAVFMAELAAPTALHMPAATHRFGGSRHPTETAYNLALNSLQPFGAAIQERPKLGRQWSAYLHHAVGLHQEKKIADMLSQLKWSSLGNSFVVEVGAQSTSMAHHLANKFPTLHLIVQIDRSRASRLNPDYLWPGEMMNGLTRDFTPQPESSPRPGSASSRVTVTYRSASMPQPVVDAAVYILHVPVLSTNSPAGADAMETVKTELQDYLGILRATAGILLIPTANLLPEPGSLSDPNFEAVARTRDLNYLQLANEGEMEMTDLFSAIETTRDGLGRLVITNQLRSHIGLTVCLTLKHETYC
What is the function of this protein?
Transcription factor that probably regulates the expression of the gene cluster that mediates the biosynthesis of notoamide, a fungal indole alkaloid that belongs to a family of natural products containing a characteristic bicyclo[2. 2. 2]diazaoctane core.
What are the official names of this protein?
Notoamide biosynthesis cluster transcriptional coactivator notR, Notoamide biosynthesis cluster protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: NANA_SALPA
Sequence: MAKALQGVMAALLTPFDHQQQLDSESLRRLVRFNIGQGIDGLYVGGSTGEAFVQSLAEREQVLEIVAEEAKGKITLIAHVGTVSTAESQQLASAAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPGVNALKQTSGDLFQMEQIRRAHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVQALREGDVAKAQRLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFAPVDEKYLPALKALAQQLMEEKA
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKA7A_HUMAN
Sequence: MGQLCCFPFSRDEGKISELESSSSAVLQRYSKDIPSWSSGEKNGGEPDDAELVRLSKRLVENAVLKAVQQYLEETQNKNKPGEGSSVKTEAADQNGNDNENNRK
What is the function of this protein?
Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel.  The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
What are the official names of this protein?
A-kinase anchor protein 7 isoforms alpha and beta, AKAP-7 isoforms alpha and beta, A-kinase anchor protein 18 kDa, AKAP 18, Protein kinase A-anchoring protein 7 isoforms alpha/beta, PRKA7 isoforms alpha/beta.
What are the subcellular locations of this protein?
[Isoform Alpha]: Lateral cell membrane; Lipid- anchor. Note=Targeted predominantly to the lateral membrane. SUBCELLULAR LOCATION: [Isoform Beta]: Apical cell membrane; Lipid- anchor. Note=Targeted predominantly to the apical membrane.
Protein: RS5_PSESM
Sequence: MSNHDQKRDEGYIEKLVQVNRVAKTVKGGRIFTFTALTVVGDGKGRVGFGRGKSREVPAAIQKAMEAARRNMIQVDLNGTTLQYAMKSAHGASKVYMQPASEGTGIIAGGAMRAVLEVAGVQNVLAKCYGSTNPVNVVHATFKGLKGMQSPESIAAKRGKRVEEII
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: URM1_CAEEL
Sequence: MSTIPVTIDFSGGAEFLVKAKAQKVQIPADSTLRDVLKFVRDNLVTDVHRINMLLNDDASEVAHGVITLINDTDTGLLLEYDTVIEAGDTITFVSTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIPL_SCHPO
Sequence: MGRYYPVHLKSRCYVCAKCKTHLAFKGHLLSHDYRGKNGPACLFKRVENVIEMEPKTEQMSTGRFIVRHIHCCRCHTYIGWKYVSSYEPSQKFKDGHYILEMQDAVLQRDDPEPDDCFIHPPITFLSSSFS
What are the official names of this protein?
Protein yippee-like PJ691.02.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
Protein: HUTI_STAAB
Sequence: MNDLIINHIAELILPRSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATETIDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLKVSNRLAEKHDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVKIHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNPGSSVTNNLQLVMAIAALKLKLSPNEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDGKVIVDNTLSFKA
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_BACAA
Sequence: MKQILFMDTTLRDGEQSPGVNLNEQEKLQIARQLERLGIHVMEAGFAAASEGDFQSVKRIANTIQNATVMSLARAKESDIRRAYEAVKGAVSPRLHVFLATSDIHMKYKLCMSKEDVLDSIYRSVTLGKSLFPTVQFSAEDATRTARDFLAEAVEVAIRAGANVINIPDTVGYTNPEEYYALFKYLQESVPSYEKAIFSCHCHDDLGMAVANSLAAVEGGALQVEGTINGIGERAGNAALEEVAVALHIRKDFYKAEPSMTLKEIKATSTLVSRLTGMVVSKNKAIVGANAFAHESGIHQDGVLKEVTTYEIIEPALVGESQNLFVLGKHSGRHAFTEKMKELGYEFTNDERDAVFEAFKKLADRKKEITEEDLRALMLGEAAFAAQQYNITQLQVHFVSNSTQCATVVLKDEEGNVFEDAATGSGSIEAIYNAIQRILGLECELADYRIQSITQGQDALAHVHVELKEGAHQVSGFGVAQDVLEASARAYVHAAGKLKSFIQLVK
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: END8_SHIDS
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKTYQSQLIGQHVTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEESQTTRVLRVKLQTADKTILLYSASDIEMLTPEQLTMHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLDIPRFSYATRGQVDENKHHGALFRFKVFHRDGELCERCGGIIEKTTLSSRPFYWCPGCQH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: Y078_NPVOP
Sequence: MNLDVPYYRLGAHERVEYIPLKLALNDDAPPPAAHEYAEARAAGGEAAPPAEQWSAGVIVLIGLVAFVALFLLLYVIYYFVILRDQPQYSDDIDNDPPFAFNKFD
What are the official names of this protein?
Uncharacterized 11.7 kDa protein.
Protein: RS9_PROMS
Sequence: MNSQIKNKAVYWGTGRRKTSVARVRLIPGNGLIKINGRSGDDYLNFNPLHLNSIKAPLQTLGLENSYDILVNVFGGGLTGQADAIKQGAARALCELSPDNRKPLKTEGHLSRDPRAKERRKYGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: PNP_RHIME
Sequence: MFETHKVEIEWAGRPLKLETGKIARQADGAVLATYGETVVLATVVSAKAPKPGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSENETLVSRLIDRPIRPLFPDGYKNDTQVIITVMQHDLENNPDVVAMVAASAALTLSGVPFMGPVGGARVGYINGEYVLNPHLDEMDESTLDLVVAGTQEAVLMVESEAKELPEDVMLGAVVFGQKGFQPVIDAVIRLAEVAAKEPREFNPEDHSALENAMLSIAEDELRNAYKITEKAARYAAVDAVKAKVKEHFLPEGVENPAHTAEEIAAVFKHLQAKIVRWNILDTKSRIDGRDLVTVRPIVAEVGILPRTHGSALFTRGETQAIVVATLGTGEDEQYVDSLTGMYKENFMLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIHPMLPTAEQFPYTLRVVSEITESNGSSSMATVCGTSLALMDAGVPLAKPVAGIAMGLIKEDDRFAVLSDILGDEDHLGDMDFKVAGTDAGITSLQMDIKIEGITEEIMGVALNQAKGGRLHILGEMAKAISESRGQLGEFAPRIEVMNIPVDKIREVIGSGGKVIREIVEKTGAKINIDDDGTVKIASASAKEIEAARKWIHSIVAEPEVGQVYEGTVVKTADFGAFVNFFGARDGLVHISQLASERVAKTTDVVKEGDKVWVKLMGFDERGKVRLSMKVVDQATGKEVVAEKSEKKDGGEAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_NEIG2
Sequence: MNGKTIILANPRGFCAGVDRAISIVERALEEFGAPVYVRHEVVHNKFVVDNLREKGAVFIEDLAEVPPGATLVYSAHGVSKAVQQEAAERGFRVFDATCPLVTKVHKEVARLDAQDCEIIMIGHKGHAEVEGTMGQLAPGKMLLVETVGDVAKLEVRNPDKLAYVSQTTLSVDETKDIIAALNARFPNIRNPHKEDICYATTNRQTAVKELAEQCDIVIVVGSPNSSNSNRLREVAASRGIDAYMVDNASYLQRTWFEGKSKVGVTAGASAPEVLVREVLATIRGWGHETVREGGGAEESIVFVLPKELRREGETKPDLCKR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: FRHA_METJA
Sequence: MEVNFVTNRIEIAPTTRHEGHAKLILEVDEEGIVNKAYYLNTTPVRGFETMLKGKPAEFAPIAVMRICGICQTTHGIASCEAIENAIDCEVPDDGLLLRELVGIGNRLHSHPLHHLLTIDDFLKPDETDLKIELIKLIQRMRKVGQLVVDIVGGEGIHPPNIVIGGMRTNITERAKSRLYYALRQYEKDAYELYEKYTELIERYLEEIGIPDLGAHEYPYIATHTTYGDRYAINWDDVTEIPAQRYYDDEEAKQTTTIQIPLYAGVPAEGGPRARMVKFGNFREGGSAMDINIARAQENLGAVYRALEILDELDLNGKTRAEVEYKDGFGIGVHEAPRATNTHMAEVGKDGKIKSYRIIAASTWNFPIVEKAIEGYPQQYAEVIMRAYDICASCATHVIVKDEETKEIIEVRKML
What is the function of this protein?
Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
What are the official names of this protein?
Coenzyme F420 hydrogenase subunit alpha, 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit alpha, FRH.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.