PharMolix/UniProtQA huggingface dataset:
Protein: IRF4_MOUSE
Sequence: MNLETGSRGSEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSVFRIPWKHAGKQDYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDPYKVYRIVPEGAKKGAKQLTLDDTQMAMGHPYPMTAPYGSLPAQQVHNYMMPPHDRSWRDYAPDQSHPEIPYQCPVTFGPRGHHWQGPSCENGCQVTGTFYACAPPESQAPGIPIEPSIRSAEALALSDCRLHICLYYRDILVKELTTTSPEGCRISHGHTYDVSNLDQVLFPYPDDNGQRKNIEKLLSHLERGLVLWMAPDGLYAKRLCQSRIYWDGPLALCSDRPNKLERDQTCKLFDTQQFLSELQVFAHHGRPAPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQNTGHFLRGYELPEHVTTPDYHRSLRHSSIQE
What is the function of this protein?
Transcriptional activator.  Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter.  Binds the immunoglobulin lambda light chain enhancer, together with PU. 1.  Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.  Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
What are the official names of this protein?
Interferon regulatory factor 4, IRF-4, Lymphocyte-specific interferon regulatory factor, LSIRF, NF-EM5, PU.1 interaction partner, Transcriptional activator PIP.
What is the protein family that this protein belongs to?
Belongs to the IRF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ECOT_ECO5E
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDTGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ADAT3_MOUSE
Sequence: MEPTSGFAEQPGPVKAESEEQEPAQWQALPVLSEQQSGAVELILAYAAPVLDKRQTSRLLREVSAVYPLPAQPHLKRVRPSRSAGGAQSSDLLLCLAGPSAGPRSLAELLPRPAVDPRGLGTPFLVPVPARPPLTRSQFEEARAHWPTSFHEDKQVTSALAGQLFSTQERAAMQTHMERAVCAAQRAAAQGLRAVGAVVVDPASDRVLATGHDCSSVASPLLHAVMVCIDLVAQGQGRGSCDLRSHPACSFTQATATQGARAGSVRKLDEDSLPYVCTGYDLYVTREPCVMCAMALVHARIQRVFYGAPSPDGALGTLFRVHARPDLNHRFQVFRGILEDQCRQLDPDP
What are the official names of this protein?
Probable inactive tRNA-specific adenosine deaminase-like protein 3, tRNA-specific adenosine-34 deaminase subunit ADAT3.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.
Protein: RSSA2_YEAST
Sequence: MSLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTYGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRLDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRNPEEVEQVAEEAAAAEEGEEEEVKEEVTEGQAEATEWAEENADNVEW
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  uS2 is required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits (PubMed:9973221, PubMed:14627813).
What are the official names of this protein?
40S ribosomal protein S0-B, Nucleic acid-binding protein NAB1B, Small ribosomal subunit protein uS2-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PSBA_NASOF
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ODA1_CHLRE
Sequence: MPSADATRGGGSAGSMGKGTLGAGDTLGHKSVLDKQRAAIEKLRAQNEQLKTELLLENKFSVRPGDPFAQALINRLQDEGDMLARKIVLEMRKTKMLDQQLSEMGSTLTTTRNNMGGIFSAKEQSTAVQKRIKLLENRLEKAYVKYNQSITHNKQLRESINNLRRERIMFESIQSNLERELAKLKRDMADMIQQANGAFEAREKAIGEMNALKAQADKEQQGFEEEWRQLTTIIEEDKKERERARAQELAMRERETQELLKMGTLSSAEKKKRITKGSWNVGYNKAMAQNVAAEKVEMYGQAFKRIQDATGIEDIDQLVNTFLAAEDQNYTLFNYVNEVNQEIEKLEDQINIMRGEINKYRETGRELDMTKSRELTEEEARLAASEAQSQLYEKRTDSALSMTTALKAGINDLFERIGCNTPAVRDLLGEEGVTEANLTAYLGIIEQRTNEILQIYAKRKAQQGTDGLAEALLAQPLTQPGNRIIIEPPSTTQEEEVEGLEPEPVEEDRPLTREHLESKVQRTLPRKLETAIKVRPAGADATGGKRGSPTRR
What is the function of this protein?
Component of the outer dynein arm complex required for assembly of the outer dynein arm-docking complex (ODA-DC) and the outer dynein arm onto the doublet microtubule.
What are the official names of this protein?
Outer dynein arm protein 1, Docking complex component 2.
What is the protein family that this protein belongs to?
Belongs to the ODA1/DCC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: ENGB_PSEFS
Sequence: MQLKNPILGLCQQSTFMLSAAKVDQCPDDEGFEVAFAGRSNAGKSSALNTLTHASLARTSKTPGRTQLLNFFKLDDDRRLVDLPGYGYAKVPIPLKLHWQRHLEAYLGGRESLKGLILMMDIRHPMTDFDLLMLDWAVASGMPMHILLTKADKLTYGAAKNTLLKVQSEIRKGWGDAITIQLFSAPKRMGLEDAYTALAGWMELADKGAEIAE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: FADJ_SALHS
Sequence: MTTTSAFMLNVRLDNVAVVAIDVPGEKVNTLKAEFAAQVRAILKQIRENKALQGVVFISAKADNFIAGADINMIGHCQNAQEAETLARQGQQLMAEIQALPVPVIAAIHGACLGGGLEMALACHRRICTDDVKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSTALDMILTGKQLRARQALKAGLVDDVVPQTILLEAAVELAKKERLAQRTLPVRERILAGPLGRALLFRLVRKKTAQKTQGNYPATERIIDVIETGLAQGSSSGYDAEARAFGELAMTPQSQALRAVFFASTEVKKDPGSDAPPGPLNSVGILGGGLMGGGIAWVTACKGGLPVRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISGSTDYRGFSHRDLVIEAVFEDLPLKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSPVEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSDKAGFYVNRILAPYINEAIRMLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVASILNDDRKGRKNGRGFYLYGEKGRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVMLMLNEAARCFDEKVIRSARDGDIGAVFGIGFPPFLGGPFRYMDALGPGEMVATLQRLAALYGPRYAPCEQLVRMAERREHFWTNGETDQGN
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_HAEDU
Sequence: MNIKNEKIAVLYGGTSQEREVSLHSGAAVTEALKSLGYNVEGIDTKDIAIEKLKEKGIQRVFNILHGGIGENGVLQGALEQMGIPYTGCGVMASAITLDKFRTKLLWNAVGLPTADMVVVQRGQAIDINQIIAKLSLPVFVKPSSEGSSVGVFKVKTKEELLPAITAALEFDTIVLVEEFLTGAEYSVPVLDGEVLPAVQIIPDGEFYDYHAKYLSDKTQYIVPALTNERQAEVAKIVKAAYDVVGCRGWSRIDVMEDQNQNFRLVEVNTNPGMTSHSIFPKSAATMGISFEKLVERVLELSI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSO1_ARATH
Sequence: MDKSQKNPTSQIGTSTPKSKFEDSPVFNYISNLSPIESVKSISTAQTFSSLSFTSPPPVFTSPHVISHRESRFFRCHNSVDRSKHLESLDGSAVKGEVVVPLVEDLNKEASLEDEEETSVETSSELPQIMKFDSQTSEHSDSPCTEDVVIEASSDPPRGDNGSSSEDVTMGLQNMLVVREGNDTPGCGRLISDATELLVFRSPNDSEAFRCLVDKISSSERRFCAGVKSTKRPDINKDIPANGSSNENQPLAVLPTNESVFNLHRGGMRRRCLDFEMPGKRKKDIVDDQQSVCDNNVAGESSSSCVVPGIGLHLNAVAMSAKDSNISVIHGYSISGEIQKSFSGSTTPIQSQDTVQETSDQAENEPVEEVPKALVFPELNLGSLKKKMRKSEQAGEGESCKRCNCKKSKCLKLYCECFAAGVYCIEPCSCIDCFNKPIHEETVLATRKQIESRNPLAFAPKVIRNADSIMEASDDASKTPASARHKRGCNCKKSNCMKKYCECYQGGVGCSMNCRCEGCTNVFGRKDGSLLVIMESKLEENQETYEKRIAKIQHNVEVSKEVEQNPSSDQPSTPLPPYRHLVVHQPFLSKNRLPPTQFFLGTGSSSFRKPNSDLAQSQNEKKPLETVTEDKTEIMPEILLNSPIANIKAISPNSKRVSPPQPGSSESGSILRRRGNGRKLILRSIPAFPSLNPNQ
What is the function of this protein?
Probable floral-specific cell division component, required for proper organ formation in flowers.  Regulates the floral meristem cell division and the inflorescence meristem organization.  Plays a role in development of both male and female reproductive tissues.
What are the official names of this protein?
CRC domain-containing protein TSO1.
What is the protein family that this protein belongs to?
Belongs to the lin-54 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHAA_RHILO
Sequence: MSSKANPPQPVATAPKRSQIPILDSTMSYVEAGASGPTVLFLHGNPTSSHIWRNIIPHVAPFGRCIAPDLIGYGQSGKPDIDYRFFDHVRYLDAFLDALDIRDVLLVAQDWGTALAFHLAARRPQRVLGLAFMEFIRPFERWEDFHQRPQAREMFKALRTPGVGEKLVLEDNVFVEKVLPASVLRAMSDDEMDVYRAPFPTPQSRKPVLRLPREMPIEGQPADVAAISAHDHRALRLSTYPKLLFAGDPGALIGPQAAREFAAGLKNCSFINLGPGAHYLQEDHADAIGRAIASWLPEVVLANQTDELA
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: RL20_HALHL
Sequence: MSRVKRGVTNRAKHKKVLKAAKGYYGMRGSAFRIARQQVIKSGQYAYAHRRLRKREFRSLWIQRINAAARQHGLSYSRLMNGLQQAGIEVDRKQLADLAVHEPQSFAALAERAQGALSN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RIBC2_RAT
Sequence: MEVAIPKDLQQEASLAKKRYMDLCRQGQIFDARNRIIGGDTQAWDVQVRNQKIKEVTEKARDETFAAEMRHNDKVMCIMHDRELRHRKQLCRAINDFQQRFQKPETRREFDLSDPLALKKELPARVSDNDMRNTISGMQKFMGEDLNFQERKRIQKEQNREWSLQQHGEWERAQAEHKLAEHLHTQTELKFDEAARDLQRLEITTRKAVCAAVKEFNKKQVVELAERKRQVKQQEQEDNMSEITNLLHGDLLSENPQQAASNFGPRHVMLDRWKGMNREQLEEIWSTWKQQIHEKLRLQEEERQHNMDWDLRRTRKAHASLLQERQQQRLLREQRRALDCSNLSLAKQQYLQKRQLDAAPSSQPTEDYFSQFNTRSR
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
RIB43A-like with coiled-coils protein 2.
What is the protein family that this protein belongs to?
Belongs to the RIB43A family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: RL16_BACHK
Sequence: MLMPKRVKYRREHRGKMRGRAKGGTEIAFGEFGLQAQAASWITNRQIEAARRAMTRYMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKIMFEIAGVSEEVAREALRLAAHKLPVKCKFVKREENGGESNEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HIS2_SALTY
Sequence: MLTEQQRRELDWEKTDGLMPAIVQHAVSGEVLMLGYMNPQALDKTIESGHVTFFSRTKQRLWTKGETSGHVLNVVSIAPDCDNDTLLVLANPVGPTCHKGTSSCFGDASHQWLFLYQLEQLLAERKTADPTSSYTAKLYASGTKRIAQKVGEEGVETALAATVNDRFELTNEASDLMYHLLVLLQDQDLNLTTVIDNLRKRHQ
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_RHOOB
Sequence: MTMPYYASAEQIMRDRSELARKGIARGRSVVVLTFRDGVLFVAENPSTALHKVSELYDRLGFAAVGKYNEFENLRRAGIVHADMRGYSYDRRDVTGRSLANAYAQTLGTIFTEQPKPYEVEICVAEVGRVGSPKAPQLYRITYDGSIVDEQHFVVMGGTTEPIATAMRESYRADLDLEAAVGIAVNALRQGGAGEGEKRNVDVASLEVAVLDQSRPRRAFRRIAGAALEQLVPAAPAAASESAPEPKPDTETKPADPQD
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_CUPPJ
Sequence: MNAPLASGRPDIQSADGIWHCCHLLPDADPDRAVRDAALVVEQGRIAWLGAEAELPADYRSLPRHDAGGTWMTPGLVDCHTHLVYGGQRADEFAMRLAGASYEEIARAGGGIVSSVRATRAADEDTLFSQAAARLAPLLAEGVTAIEIKSGYGLELEAERRQLRVARRLGEAFGVSVHTTFLGAHALPPEYAGRADDYIDLVCNTMLPALAEEGLVDAVDAFCESVGFSLAQTERVFEAAARHGLRVKLHAEQLSNLGGAALAARHHALSADHLEHLDEAGVEAMAAAGTVAVLLPGAYYFLRDTNLPPIALLRKHGVPIAISTDHNPGTSPVTSLLLMMNMACTLFRLTVPEALAGVTTHAARALGAPDRHGKLAVGRAADFVLWRVESPAELAYWFGRNPAAVVVRQGRIHPATSQHGGRA
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_XANAC
Sequence: MRRKIVAGNWKLHGSRAFATELVAKVAAHMPLEGVEVVILPPLPYLGDLIEDFEAHHLSFGAQDVSSNEKGAYTGEVSASMLVDVGAGYGLVGHSERRQYHQESSELVARKFAAALHAGLIPVLCVGESLEQREAGQTEAILRAQLDPVLALVGSAGFAGAVLAYEPIWAIGTGRTATPEQAQAVHAFLRGEVAKADARIADSLPILYGGSVKPDNAGELFAQPDVDGGLVGGASLVAEDFLAIARAAAAC
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS2_LEMGI
Sequence: MASSMMASTAAVARAGPAQSNMVAPFNGLRSSVAFPATRKANKNLSTLPSNGGKVSCMQVWPPEGLKKFETLSYLPPLSVEDLAKEVDYLLRNDWVPCIEFSKEGFVYRENHASPGYYDGRYWTMWKLPMFGCTDASQVIAEVEEAKKAYPEYFVRIIGFDNKRQVQCISFIAYKPT
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 2, RuBisCO small subunit 2, RuBisCO small subunit SSU26.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GBRT_MOUSE
Sequence: MGIRGMLRAAALLLLIRTWLAESNGPSPTPKFHFELSSSTPEVILDLFNCKNCANEAVVQKILDRVLSTYDVRLRPNFGGAPVPVSVSIYVSSIEQISEINMDYTITMFLHQTWKDTRLAYYETNLNLTLDYRMHEKLWVPDCYFVNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLQKFPMDKQSCKLEVESYGYTVEDIVLSWEDDNAIHITDGLHIPQYTYLGRTITSKEVYFYTGSYMRLIVKFQVQREVRSYLVQVYWPTVLTTILSWISFWMNYDSSAARVTIGLTSILVLTTIDSHMRDKLPHISCIKAIDIYILVCLFFVFLSLLEYVYINYLFFSQVPRRNHRRCRKPRRVVARYRYQEVVVANVQDGLINVEDRVEDRAGPLPDSPMQAHLASQESLGSLVFTSEQAQLATSESLSLLSSASSQTQLATGESLSDLPSTSEQTVPECTIHFHGFLTNDSIIPIKIHSRSDACDDEDSEESLSSEESHGHGSSHTGRLKLQISQRCVQEASWDLDKIEILQDDISITSSWLGLDEQCKGDADSIWSLTDEELMACDQEKDSSSESEENCSPSPGCSFNEGFSFQLFKPNRVPKVDRWSRFLFPLSFGLFNVVYWLYHVY
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit theta, GABA(A) receptor subunit theta.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRQ sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RS7_METST
Sequence: MSFKLFDKWDVTEVTVEDMGLQNYVCLDEIVVPHTMGRHVKRQFAKSKVSIVERLMNKIMRTERNSGKKNKAYSIVEDALEIINNKTKQNPVQVLVKAVENTAPREETTRIKYGGIGYQIAVDIAPQRRVDLSLGFITKGAMQSAFKNKKSAAQCLADEILLASDEDSRSFAVQKKEEKERVARSAH
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RNH_SHIDS
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXAC_RHIME
Sequence: MRGLIDPDLLFPAEERTRALARRLYAEVSGLPIVSPHGHTEPRWYALDEAFPDPAQLLIVPDHYVFRMLFSQGIRLEELGVPALDGSPVETDGRAIWRRFCENYHLFRGTPTRLWFDYTLSELFGIDELPSAASSDPLYDHVAECLTRPDYRPRALYERFNIEVISTTDSALDDLGWHAKILESGWKGRVVPAYRPDAVVDPDFQGFPTNLDKLGDITGADTGTWSGYLDAHRTRRAYFKDFGATSTDHGHATADTANLPQAEAAALFDKVRLGKANADERRLFRAQMLTEMAKMSLDDGLVMQIHPGSFRNHSPAILAKFGRDKGFDIPTRTDYVTALKPLLDAVGLERDLTVILFTLDETSYARELAPLAGVYPALKLGPAWWFHDSAEGMRRFREMTTETAGFYNTVGFNDDTRAFPSIPARHDIARRVDCAFLARLVAEHRLREDEAYELARDLAYGLAKEAYRL
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: RHAT_ECOL6
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MFSD5_TAKRU
Sequence: MFVTAYFAVISLLALCVGLELTARRLTPPESSAAVNPAFRRFQATFLRAYLLALWADWLQGPYLYKLYRHYSFLESQIAILYVCGLASCVLFAPFSGWLSQALGRRHMCIFFCLSYATCCLTKLSRDYFVLIVGRILGGLSTSLLTTTFESWYVHHHVEIHDFPKEWIPTTFTKAATWNHGLAVGAGLVANLLAEWLHLGPVAPFLLAVPFLACCAWFVLTDWAKEEAEKSPEGIKQTLPLGTLNGGVTHLSARARFSRSCSDGLRCMLSDKRVMLLGGVQALFESVLYIFIFLWTPVLDPHGSPLGIVFSCFMAASMVGSLLFRVATSTRYHLQPGHVLCVAVLMAFFSFFMLTFSTVPGQPRPHESFLAFLLLELACGLYFPALNFLQGRIIPEEKRASVLAWFRLPLHLLACLGLLALHGEVSGTGAGETGSGTRHMFGGCAVMMLAALMAVVSLFTLGRNDTDLKLEGSRGEGEMY
What is the function of this protein?
Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
What are the official names of this protein?
Molybdate-anion transporter, Major facilitator superfamily domain-containing protein 5, Molybdate transporter 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GYRA_THEMA
Sequence: MPEILINKPVEDELVESYLLYSMSVIVGRAIPDVRDGLKPVQRRILYGMYELGLKHNSPTKKSARIVGEVMGKYHPHGDAPVYDALVRMAQPFTMRYPLIEGQGNFGSIDRDPPAAMRYTEARLTRLAEEMLEDIEKNTVNMIDNFDGTLKEPEVLPSKVPNLIINGASGIAVGMATNIPPHNLSETVDALIYLIDHPEATVEELMQFIKGPDFPTGAVVVNASELKKVYEEGRGRIIVRGKVHVEDGKRVKRIVITEIPYGVSKAGLIEQIAKIAKDDESLPIRNIRDESDKRGMRIVIEIPKDANEEVIINNLYKRTALQDYFNVQMLVIDKHKRPRLMNLKGLMEAFLEHRFEVIRRRARYEYEQYTRRAHVVEGLLKAARAIGVVVDIVRNSKDVESARQSLMETLEITEEQAKAILDMRLSRLTSLEIENLQNEYSDLVRKISEVKEILEKDEKVKEIMKKEFLYLKQQYGDPRRTEVTDQSIEYNEEELIVEEDVVITLSHKGYLKSTPLNSYRSQKRGGKGITVSKLSEDDEVEFVVVAKNTSSTLFITNLGRAYVLKNYQLETTGRNTRGRHITAFLNLEDTEKIVALASLNGEGRDLVIATKSGKIKRTALKEFENATSNRGVRAIKIEPGDEIVSARVVNSEKETLIVATKMGMAIRFPVSDVRRMGRNAAGVQAIKLQPGDEVVSVDVIPPGEEGEILTVTEKGFGKRTPVQLYRIQRRGGTGLRNISDVNKTGYVVAVRYVRGDEEIVVVTRNGMMIRFPVSEIGVIGRVTKGVKLIELGDDTISKVAVVKD
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USPB_ECOSE
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.