PharMolix/UniProtQA huggingface dataset:
Protein: RECA_HELPS
Sequence: MAIDEDKQKAISLAIKQIDKIFGKGALVRLGDKQVEKIDSISTGSLGLDLALGIGGVPKGRIIEIYGPESSGKTTLSLHIIAECQKNGGVCAFIDAEHALDVHYAKRLGVDTENLLVSQPDTGEQALEILETITRSGGIDLVVVDSVAALTPKAEIDGDMGDQHVGLQARLMSHALRKITGVLHKMNTTLIFINQIRMKIGMMGYGSPETTTGGNALKFYASVRIDIRRIAALKQNEQHIGNRAKAKVVKNKVAPPFREAEFDIMFGEGISKEGEIIDYGVKLDIVDKSGAWLSYQDKKLGQGRENAKALLKEDKALANEITLKIKESIGSNEEIMPLPDEPLEEME
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3797_RHIE6
Sequence: MSDAHGVARDQLRAFIERIERLEEEKKTIADDIKDVYGEAKGMGFDTKILKKVVALRKKDEQERMEEEAILDTYLHALGMIESPPEG
What are the official names of this protein?
UPF0335 protein RHECIAT_CH0003797.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: GRAP_BOVIN
Sequence: MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGAEGFVPKNYIRLKPHPWYSGRISRQLAEEILMKRNHQGAFLIRESESSPGEFSVSVNYGDQVQHFKVLRDPSGKYYLWEEKFNSLNELVAFYRTTTIAKKRQVFLQDEEPLPKPPRACFAQAQFDFSAQDPSQLSFRRGDIIEVLERLDPSWWRGRLSGRIGFFPRSYVQPVHM
What is the function of this protein?
Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.  Plays a role in the inner ear and in hearing.
What are the official names of this protein?
GRB2-related adapter protein.
What is the protein family that this protein belongs to?
Belongs to the GRB2/sem-5/DRK family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Synapse. Note=Localizes at the presynaptic terminal.
Protein: G6PI_MYCBO
Sequence: MTSAPIPDITATPAWDALRRHHDQIGNTHLRQFFADDPGRGRELTVSVGDLYIDYSKHRVTRETLALLIDLARTAHLEERRDQMFAGVHINTSEDRAVLHTALRLPRDAELVVDGQDVVTDVHAVLDAMGAFTDRLRSGEWTGATGKRISTVVNIGIGGSDLGPVMVYQALRHYADAGISARFVSNVDPADLIATLADLDPATTLFIVASKTFSTLETLTNATAARRWLTDALGDAAVSRHFVAVSTNKRLVDDFGINTDNMFGFWDWVGGRYSVDSAIGLSLMTVIGRDAFADFLAGFHIIDRHFATAPLESNAPVLLGLIGLWYSNFFGAQSRTVLPYSNDLSRFPAYLQQLTMESNGKSTRADGSPVSADTGEIFWGEPGTNGQHAFYQLLHQGTRLVPADFIGFAQPLDDLPTAEGTGSMHDLLMSNFFAQTQVLAFGKTAEEIAADGTPAHVVAHKVMPGNRPSTSILASRLTPSVLGQLIALYEHQVFTEGVVWGIDSFDQWGVELGKTQAKALLPVITGAGSPPPQSDSSTDGLVRRYRTERGRAG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1252_BACC4
Sequence: MQNKIQVKSVEKRENALIFCAENSEIEVKELSARNHVLVDSDNLSFLYILENESSFIYVSIPHTCWEAMHEAMNNDVVMFVRVNDIEMELEGLKEEVEYLVENIEGNANYGEELVTAVEKVFL
What are the official names of this protein?
UPF0738 protein BCB4264_A1252.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: SYM_CAUSK
Sequence: MARILITSALPYINGVKHLGNLAGSMLPADVYARFQRARGNDTLYICATDEHGTPAELAAAAAGQDVAEYCAEQHVLQHDVGRAFGLSWDHFGRSSSPQNHRLTQHFCEVLEERGLIEERVDQMVYSIDDARFLPDRYIEGTCPHCGFDKARGDQCDNCGNLLDPTELKDPYSVISGSRNLEVRDTRHLYLLQTKMADKIRAWIDSHPDWQLLAKSIAYKHLDEGLIDRGITRDLAWGIPVTKGEFPRPGFEDKVFYVWFDAPIEYIAATQEWADEGAGRDWKSWWRTDEGADDVRYVQFMGKDNVAFHTVSFPATILGSQEPWKSVDMLKAFNWLNWYGGKFSTSNKRGVFMDAALEILPPDFWRWYLTSNAPESSDTAFTWEQFASAVNRDLADVLGNFVNRILKFTEGKFDGVIPDGGAPGPLEEKLYADVSARLADLTEQMDAVEVRKSAQALRALWVVGNEYLQEAAPWTAIKTDRDRAAVIVRTALNLAALYARISAPFIPFAAEKIGEAFQLPWPPVWPTTDAAAELSSLPVGLSVRAPEVLFKKIEDEQIAEWTRRFGGAE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFG1_RAT
Sequence: MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQENRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEDTSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSSDSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW
What is the function of this protein?
GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1).  Involved in membrane trafficking and /or vesicle transport.  Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment.  Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2.  Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated.  Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine.
What are the official names of this protein?
ADP-ribosylation factor GTPase-activating protein 1, ARF GAP 1, ADP-ribosylation factor 1 GTPase-activating protein, ARF1 GAP, ARF1-directed GTPase-activating protein.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Note=Associates with the Golgi complex.
Protein: EFGM_SCHPO
Sequence: MLKLSFRSLTSRLPRLSTLVVRGYASVANTGIEASNTSENNLNIQEQLNDNDKKRLKQIRNIGISAHIDSGKTTFTERVLYYTGRIKDIHEVRGKDNVGAKMDFMELEREKGITIQSAATHCTWERTVDQIEANEKQKTDFEKSYNINIIDTPGHIDFTIEVERALRVLDGAVLVLCAVSGVQSQTITVDRQMRRYNVPRISFVNKMDRMGADPWKVIQQINTKLKIPAAAVQIPIGQEDKLEGVVDLIQMRAIYNRGSKGEKIEISQQVPENLIELAKEKRSALIEKLADLDEEIADIYVMEEDPTPEQLMGAIRRTTLARKFTPVLMGSALSNVGVQSVLDAVCDYLPNPSEVENIALNAADSEKPVSLVPSSEKPLVALAFKLEEGRFGQLTYLRIYQGTLKRGNYIYNVNSTKKIKVSRLVRMHSNDMEEIEKVEAGGICALFGIECASGDTFTDGSVSYTMTSMFVPEPVISLSLKPKSKDTTSFSKALNRFQREDPTFRVQLDNESKETIISGMGELHLEVYVERMRREYKVDCETGKPRVAFRETLSKKVPFSYLHKKQSGGAGQYAKVEGYIEYMDGVEDESGNVVDCEFINKVTGGTVPTQYIPACEKAFYEALKKGFLIGHPIKNCRFVLEDGAYHPVDSSELAFRLATISAFRTAFLQANPMVLEPIMNVSITAPVEHQGGVIGNLDKRKATIVDSDTDEDEFTLQAEVPLNSMFSYSSDIRALTKGKGEFSMEFLKYLPAPKYVQKELVDAYNKQQQK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GLYA_CHLPN
Sequence: MVSLLHKFLENASGKKGQSLASTAYLAALDHLLNAFPSIGERIIDELKSQRSHLKMIASENYSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVDAIEWECVETAKELFAADCACVQPHSGADANLLAVMAILTHKVQGPAVSKLGYKTVNELTEEEYTLLKAEMSSCVCLGPSLNSGGHLTHGNVRLNVMSKLMRCFPYDVNPDTECFDYAEISRLAKEYKPKVLIAGYSSYSRRLNFAVLKQIAEDCGSVLWVDMAHFAGLVAGGVFVDEENPIPYADIVTTTTHKTLRGPRGGLVLATREYESTLNKACPLMMGGPLPHVIAAKTVALKEALSVDFKKYAHQVVNNARRLAERFLSHGLRLLTGGTDNHMMVIDLGSLGISGKIAEDILSSVGIAVNRNSLPSDAIGKWDTSGIRLGTPALTTLGMGIDEMEEVADIIVKVLRNIRLSCHVEGSSKKNKGELPEAIAQEARDRVRNLLLRFPLYPEIDLEALV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1099_ARATH
Sequence: MNLLQSCKDMAMMMRIDSVSHITNTALLPCLYNGTVLRRRSLSLRKCGFRERKFQLRCVSASSDSLQFDFSPPPIDHDFLDTISVSGGKVSEDGVVESFDNDDEALDAFDNGVVVVDLSHFGRIRVSGDDRAHFLHNQTTANFESLYEGQGCDTVFVTPTARTIDIAHAWIMKNAILLTVSPTTCQSIIEMLNKYIFFADKVEIKDITKQTCLFALAGPKSNQIMSKLNLGDLIGQPYGRHQHYSFDGMPITVGVGSLISDEGFTMLMSPGGAVSVWKTLLAEGAIPMGSVAWEKLRITQGRPAPERELSKEFNVLEAGLWNSISLNKGCYKGQETIARLMTYDGIKQRLCGLNLSAPSEPGSTITVDGKKVGKLTSYTGGKNGSGHFGLGYIKKQAASIGNTVTVGEDISGIVSEVPYLARQHPPSANSSS
What is the function of this protein?
Folate-dependent protein involved in Fe/S cluster biogenesis.  Functionally complements an E. coli mutant defective in ygfZ.
What are the official names of this protein?
Putative transferase At1g60990, chloroplastic, Iron-sulfur cluster assembly factor homolog COG0354.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RL2_LAWIP
Sequence: MAIRNLKPTSPGCRFQTISDFKEITCSSPEKSLTYGLCKKAGRNNHGHITSRRRGGGAKRLYRLIDFKRDKVGVPAKVAQIEYDPNRTARIALLHYVDGEKRYILAPVGIKQGDIIETGVDADIKPGNSLPMLHIPIGTLIHNIELNPGRGGQLCRSAGAYAQLVAREGKYALLRMPSGEVRKVLASGAATVGQVGNIHHENISLGKAGRNRWLGRRPKVRGVAMNPVDHPLGGGEGRSSGGRHPVSPWGMPTKGYKTRDKKKPSSRLIVKRRGQK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SEC23_CRYNB
Sequence: MNFEDIEDKDGVRFSWNVWPSSRLEATRTVVPISALYTPLKEREDLPPVMYEPVTCKGSSCKAILNPYCQVDVRGKMWICPFCLQRNPFPPHYHQDLSPNNLPPELLPKFTTIEYTLSRPAQIPPIFLYVVDTCVDEDELKALKETLVVSLSLLPPNALVGLITYGTMAMVHELAYADCPKAYVFRGSKDYQPKQIADMLGLNPSNRPIQPVRPGQPMPAPAASKFLMPVQACEFQLTNILEQLQRDPWPVEQDKRPLRCTGVALSVAVSLLETAFPNTGARIMLFSGGPATDGPGMVVGPELREPIRSHHDIDRDSVKHFKRASKFYEALSKRASVNGHAIDIYAGCLDQVGLLEMKSLTNATNGVMTISDSFMTAIFKQSFLRTLGKDEQGYLKMGFNATYDVLTTKELKISGVIGHVISANKKSSCVGETEIGIGQTSAWKVCSLTPKSTLATYFEVVTPAGQALTPNQSGLIQFVTHYQHSSGQYRLRVTTVSRVFQEGGHPSIAASFDQEAAAVLMARIAVFKAEIDDSPDVLRWLDRMLIRLCQKFADYRKEDPTSFQLSPNFSIYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNDSDVNNSLIMIQPTLMSYGFDSEPHPVLLDSVSIRPDVILLLDTFFHILIFHGETIAQWRKANYQEQEDYANFKELLEAPIGDAQELLEDRMPIPRYVVCDQGGSQARFLLSKLNPSTTHMSGSNYGAGPAGGQAIFTDDVSLQVFMEHLKRLAVGASTS
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC23.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GUN_PHACE
Sequence: MQVIVLPLVFLATFATSGSLAAPDASPEIVPVDGGLSGYGTTTRYWDCCKPSCAWKENINTPTMTPVQTCAIDGNTVVNASVQSGCIGGSSYMCSNQQAFVVNSTLAFGFAAGSFTGGVDNNLCCSCMLLTFQGQLAGKQFLVQITNTGGDLGSTSSIWPFPGGGVGIFTQGCHDQWTPRGAAGGDQYGGVYSVEQCSDLPEVLQPGCRFRFEFLENVSNPQVSFQQVQCPAEIVAISNCAL
What are the official names of this protein?
Endoglucanase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 45 (cellulase K) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y057_OSHVF
Sequence: MTDAVKKIAKLVVDLHGEKNTQNIIEVAKAGGKESAEAVLFKKLTDAIIKDMTAMINHGDSKEKMQFTSTEQDLPMAEDTTLTNNKLFWFSVVVGIVLFVTAINYLLDKVCWIKAARKIAITCFLISVCWNYINIYEKTMAKRYMVIRQGIPGGCMERGADWSTVLRTMFKTLMITHSDSNDECLQYAKSIIVEPLFEVTPTTALATTISDLILVPINLAAKSCNNVFRTVFEGVPVFMIPILVFLLVYISTLCIISTKRYTISVPFLLELKPCLVEPPPMVPISVRNETCNVVHKKPVALRRGLCYNKLFRNKKY
What are the official names of this protein?
Putative transmembrane protein ORF57.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: ATPI_PLAOC
Sequence: MNVLPCSINTLKGLYDISGVEVGQHFYWQIGGFQVHAQVLITSWVVIAILLGSATVAVRNPQTIPTDGQNFFEYVLEFIRDLSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALPTSVAYFYAGLTKKGLGYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPSVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LYSC_FELCA
Sequence: KIFTKCELARKLRAEGMDGF
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: THIC_BURPS
Sequence: MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLAGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: DNLI1_THEPD
Sequence: MALFRELVEAAEAAGRVSGRKEKVRILSEFLGRLSPEEASIAARFLAGHVFPEYDNRELGVGYSLVREALKVLDQKPLFLVEPQPPAITEVYRLLERIAGVSGEGSREKKLKLLEGLFSRLSRKEVEYLLRILFGEVRIGASTGLLLEAISRLSGVPYGDVLHAYMVLSDVGDVAFKALESPAALGKVDVSLFHPVKPMLADMAYNVDELFQEHGSPLHLEYKYDGLRVQIHMGRGKVRVFSRRLSDITEYVPDVVERAVEGLHVEEAVVDGEAVAVIGGAPVPFQELLRRVRRKNEREDFLKSLPFELHLFDVIYLNGKSLVREPYSTRSRLLREIVVSEEILAKKTVAYTRQEALEFYESAVRSGNEGVMSKRHSSVYKPGIRGSDWLKLKSFDTIDCVIIAAEWGHGRRSGWLSDYHLGVYDEESGRFLSVGKTFKGLSDAEFEEMTKRLLQLKVREEGYVVYVKPEIVVEVDYSEIQRSKRYPSGFALRFARIRRIRFDKSPYEVTTLRELRERYLRSIRAKRWSPQ
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase 1, Polydeoxyribonucleotide synthase [ATP] 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: GL11_ORYSJ
Sequence: MARVQLWVAAACAVVLALAAPSLAGDPDMLQDVCVADLASPVKLNGFPCKANVTADDFFFAGLKNPGNTNNPAGSNVTAANVQSFPGVNTLGVSMARIDYAPGGQNPPHTHPRATEIIFVLEGVLEVGFITTANKLFTKTVTAGEVFVFPRGLVHFQQNRGHGPAAVIAAFNSQLQGTQAIAATLFAAAPPVPSDVLAKAFRVDVPQVDAIKAKFK
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 1-1, Germin-like protein 4, OsGER4.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: PKS3_ALOAR
Sequence: MGSLSDSTPLMKDVQGIRKAQKADGTATVMAIGTAHPPHIISQDSYADFYFRVTNSEHKVELKKKFDRICKKTMIGKRYFNFDEEFLKKYPNITSFDKPSLNDRHDICIPGVPALGAEAAVKAIEEWGRPKSEITHLVFCTSGGVDMPSADFQCAKLLGLRTNVNKYCIYMQGCYAGGTVMRYAKDLAENNRGARVLMVCAELTIIALRGPNDSHIDNAIGNSLFGDGAAALIVGSDPIIGVEKPMFEIVCAKQTVIPNSEEVIHLHLRESGLMFYMTKDSAATISNNIEACLVDVFKSVGMTPPEDWNSLFWIPHPGGRAILDQVEAKLKLRPEKFSATRTVLWDYGNMISACVLYILDEMRRKSAAEGLETYGEGLEWGVLLGFGPGMTIETILLHSLPPV
What is the function of this protein?
Catalyzes the iterative condensations of 6, 7 or 8 molecules of malonyl-CoA to produce various aromatic polyketides.  Produces the heptaketide aloesone, the aglycone of aloesin, from 7 molecules of malonyl-CoA as a major product.  Also able to produce a hexaketide pyrone, a heptaketide 6-(2-acetyl-3,5-dihydroxybenzyl)-4-hydroxy-2-pyrone, a novel heptaketide 6-(2-(2,4-dihydroxy-6-methylphenyl)-2-oxoethyl)-4-hydroxy-2-pyrone and octaketides SEK4/SEK4b.
What are the official names of this protein?
Aloesone synthase, Polyketide synthase 3.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: SIR5_CANLF
Sequence: MQPLQIAPCRLLYGLYRGLKSPASTGTRICPAMARPSSNMADFRKLFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPQAFARNPSLVWEFYHYRREVMLSKEPNPGHLAIAECEARLREQGRRVMVITQNIDELHRRAGTKNLLEIHGSLFKTRCTSCGIVAENYKSPICPALSGKGAPDPEAQDARIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDKELTLCDLCLVVGTSSVVYPAAMFAPQVSARGVPVAEFNMETTPATNRFRFHFQGPCGTTLPEALAPHETGNVS
What is the function of this protein?
NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins.  Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting.  Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species.  Activates SHMT2 by mediating its desuccinylation.  Modulates ketogenesis through the desuccinylation and activation of HMGCS2.  Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.  Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.
What are the official names of this protein?
NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5, SIR2-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm, cytosol. Nucleus. Note=Mainly mitochondrial. Also present extramitochondrially, with a fraction present in the cytosol and very small amounts also detected in the nucleus.
Protein: MDTL_ECOSM
Sequence: MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWTMATMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA
What is the function of this protein?
Confers resistance to chloramphenicol.
What are the official names of this protein?
Multidrug resistance protein MdtL.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS1_MYCTO
Sequence: MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVEFFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRYAAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISVQLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGTDGQDQTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIAPLADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACOC_PSEPU
Sequence: MSQIHTLTMPKWGLSMTEGRVDAWLKQEGDEINKGDEVLDVETDKISSSVEAPFSGVLRRQVAKPDETLPVGALLAVVVEGEAEESEIDAVVQRFQAEFVAEGGADQAQGPAPQKAEVGGRLLRWFELGGEGGTPLVLVHGFGGDLNNWLFNHPALAAERRVIALDLPGHGESAKALQRGDLDELSETVLALLDHLDIAKAHLAGHSMGGAVSLNVAGLAPQRVASLSLIASAGLGEAINGQYLQGFVAAANRNALKPQMVQLFADPALVTRQMLEDMLKFKRLEGVDEALRQLALAIADGDRQRHDLRSVLGQHPALVVWGGKDAIIPASHARKGPEAEVLVLPEAGHMVQMEAAEQVNQQMLAFLRKH
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system, Acetoin dehydrogenase E2 component, Dihydrolipoamide acetyltransferase component of acetoin cleaving system.
Protein: SCAS_MESMA
Sequence: MKTVIFLIVSSLLLIGVKTDNGYLLDKYTGCKVWCVINNESCNSECKIRGGYYGYCYFWKLACFCQGARKSELWNYNTNKCNGKL
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  It binds to distinct receptor sites of mammal and insect voltage-gated sodium channels.  It displays antinociceptive effect in rat models, which is due to its specific modulation of sodium channels of sensory neurons.  It also significantly stimulates the binding of [3H]-ryanodine to ryanodine receptors on the sarcoplasmic reticulum of the skeletal muscle through an indirect mechanism.  And it promotes noradrenaline release from the rat hippocampus slice.
What are the official names of this protein?
Beta-toxin BmKAS, BmK AS, BmK-AS, BmK-PL.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.