PharMolix/UniProtQA huggingface dataset:
Protein: HSLU_STAAR
Sequence: MDTAGIRLTPKEIVSKLNEYIVGQNDAKRKVAIALRNRYRRSLLDEESKQEISPKNILMIGPTGVGKTEIARRMAKVVGAPFIKVEATKFTEVGYVGRDVESMVRDLVDVSVRLVKAQKKSLVQDEATAKANEKLVKLLVPSMKKKASQTNNPLESLFGGAIPNFGQNNEDEEEPPTEEIKTKRSEIKRQLEEGKLEKEKVRIKVEQDPGALGMLGTNQNQQMQEMMNQLMPKKKVEREVAVETARKILADSYADELIDQESANQEALELAEQMGIIFIDEIDKVATNNHNSGQDVSRQGVQRDILPILEGSVIQTKYGTVNTEHMLFIGAGAFHVSKPSDLIPELQGRFPIRVELDSLAVEDFVRILTEPKLSLIKQYEALLQTEEVTVNFTDEAITRLAEIAYQVNQDTDNIGARRLHTILEKMLEDLSFEAPSMPNAVVDITPQYVDDKLKSISTNKDLSAFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAG_XMRV4
Sequence: MGQTVTTPLSLTLQHWGDVQRIASNQSVDVKKRRWVTFCSAEWPTFNVGWPQDGTFNLGIISQVKSRVFCPGPHGHPDQVPYIVTWEALAYDPPPWVKPFVSPKPPPLPTAPVLPPGPSAQPPSRSALYPALTPSIKSKPPKPQVLPDSGGPLIDLLTEDPPPYGAQPSSSARENNEEEAATTSEVSPPSPMVSRLRGRRDPPAADSTTSQAFPLRMGGDGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLITHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVNAAFPLERPDWGYTTTEGRNHLVLYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKSKTLGDLVREAEKIFNKRETPEEREERIRREIEEKEERRRAEDEQRERERDRRRHREMSKLLATVVIGQRQDRQGGERRRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLGD
What is the function of this protein?
Involved in the packaging and encapsidation of two copies of the genome (By similarity).  Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome (By similarity).  This binding is dependent on genome dimerization (By similarity).  Acts as a nucleic acid chaperone which is involved in rearrangement of nucleic acid secondary structures during gRNA retrotranscription (By similarity).
What are the official names of this protein?
Gag polyprotein, Pr65gag, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. Host late endosome membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p10]: Virion.
Protein: RPOA_HELPJ
Sequence: MKVIKTAPLIPSEIKVLEKEGNRVKISLAPFEFGYAVTLAHPIRRLLLLSSVGYAPVGLKIEGVHHEFDSLRGVTEDVSLFIMNLKNIRFIAKALVGQDSSLENQSVVVDYSFKGPMELRARDLNSDHIEIVNPEMPLATINEDAQLNFSLIIYKGMGYVPSENTRELMPEGYMPLDGSFTPIKNVVYEIENVLVEGDPNYEKIIFDIETDGQIDPYKAFLSAVKVMSKQLGVFGERPIANTEYSGDYAQRDDAKDLSAKIESMNLSARCFNCLDKIGIKYVGELVLMSEEELKGVKNMGKKSYDEIAEKLNDLGYPVGTELSPEQRESLKKRLEKLEDKGGND
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: NADE_CHLPD
Sequence: MNSLDLHLDYGIVEDILKTFLLNEIRKFGFRSVVLGLSGGIDSAVVCELASRALGSDQVLALMMPYRSSSTDSIVHAQLLVEKLGIRAETCSITAAVDAFFEGVPEEDRLRRGNIMARTRMVYLYDVSARQNSLVVGTSNKTELLLGYGTLFGDMASAVNPVGDLYKTQIRGLARHLGIPEQLITKTPSADLWEGQSDEADLGFSYDEVDHLLFMMLEKRMDKAAIIEQGVSEIFYDRVRKMVVRNQYKRMMPVIAKISSRTPGIDFRYARDWQEVK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: PYRG_PROM2
Sequence: MSKFVFVTGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYLNVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTAMTRLNSVTTGSIYQAVINKERRGSYNGGTVQVIPHITGEIRERIHRVAANSNADIIITEIGGTVGDIESLPFLEAIREFKNDVNRNDVAYIHVTLLPFIKTSGEIKTKPTQHSVKELRSIGIQPDLLVCRSDKSINEGLKKKLSGFCGVNIKSVIEALDADSIYSVPLALKKEGLCKETLKYLELEDKECDLKNWEALIHNLRNPGDPIKVALVGKYIELGDAYLSVVEALRHACIEKKASLDLHWVSAEMIEKGSAETYLKEVDAIVVPGGFGNRGVNGKISAIKFAREKKIPFLGLCLGMQCAVIEWARNVANLPDASSSELNPDTPNPVIHLLPEQEDVVDLGGTMRLGVYPCRLTNNTTGKKLYDEDVIYERHRHRYEFNNYYKQSFLNSGYKISGTSPDGRLVELIELENHPYFLACQYHPEFLSRPGKPHPLFQGLIKASQEKLTQSN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NHAA_VIBC1
Sequence: MNDVIRDFFKMESAGGILLVIAAAIAMTIANSPLGESYQAMLHTYVFGMSVSHWINDGLMAVFFLLIGLEVKRELLEGALKSKETAIFPAIAAVGGMLAPALIYVAFNAGDPEAISGWAIPAATDIAFALGIMALLGKRVPISLKVFLLALAIIDDLGVVVIIALFYTGDLSTMALLVGFAMTGVLFMLNAKEVTKLTPYMIVGAILWFAVLKSGVHATLAGVVIGFAIPLKGKKGEHSPLKHMEHALHPYVAFGILPLFAFANAGISLEGVSMSGLTSMLPLGIALGLLVGKPLGIFTFSWAAVKLGIAKLPQGVNFIHIFAVSVLCGIGFTMSIFISSLAFANVSPEFDTYARLGILMGSTTAAIIGYVLLHFSLPKKAVEEVASEKNA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACCD_FAGEA
Sequence: MEKWWFNSMLSKEELGHRCGLSKSMDSLDPIDNINSNENMILNFTEKSIHSWSNGSSYSNLDLLFIIGDIPNLISDETFLIRDRKGETYSVYFDIENKIVEIDNYHSFSNYWNSSYGTGSKSNDTHYDLYMYDTKSSLNNHINGCIDSYLHSQMRLDNYVLRDSDHYGDNYIFDDIKTTTKTNGRDKNLEVTKKYRNLWIQCENCYELNYKKLLKSKMRICDECGYHLKMSSSERIELSIDPGTWEPMDEDMVSTDPIEFHSQEEPYKDRINSYQKETGLTDAVQTGIGQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLAEYATNQNLPLIIVCASGGARMQEGSLSLMQMAKISSALFDYQSNKKLFYVSILTSPTTGGVTASFGMLGDIIISEPSAYIAFAGKRVIEETLNTTVPEGSQEAEYLFDKGLFDPIVPRNPLKGVLSELFRLHAFFPLNQNSIGQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: NCAP_SEOUS
Sequence: MATMEEIQREISAHEGQLVIARQKVKDAEKQYEKDPDDLNKRALHDRESVAASIQSKIDELKRQLADRLQQGRTSGQDRDPTGVEPGDHLKERSALSYGNTLDLNSLDIDEPTGQTADWLTIIVYLTSFVVPIILKALYMLTTRGRQTSKDNKGMRIRFKDDSSYEDVNGIRKPKHLYVSMPNAQSSMKAEEITPGRFRTAVCGLYPAQIKARNMVSPVMSVVGFLALAKDWTSRIEEWLGAPCKFMAESLIAGSLSGNPVNRDYIRQRQGALAGMEPKEFQALRQHSKDAGCTLVEHIESPSSIWVFAGAPDRCPPTCLFVGGMAELGAFFSILQDMRNTIMASKTVGTADEKLRKKSSFYQSYLRRTQSMGIQLDQRIIVMFMVAWGKEAVDNFHLGDDMDPELRSLAQILIDQKVKEISNQEPMKL
What is the function of this protein?
Encapsidates the genome protecting it from nucleases (Probable).  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication (Probable).  The nucleocapsid has a left-handed helical structure (By similarity).  As a trimer, specifically binds and acts as a chaperone to unwind the panhandle structure formed by the viral RNA (vRNA) termini (By similarity).  Involved in the transcription and replication initiation of vRNA by mediating primer annealing (By similarity).  Plays a role in cap snatching by sequestering capped RNAs in P bodies for use by the viral RdRp during transcription initiation (By similarity).  Substitutes for the cellular cap-binding complex (eIF4F) to preferentially facilitate the translation of capped mRNAs (By similarity).  Initiates the translation by specifically binding to the cap and 40S ribosomal subunit (By similarity).  Prevents the viral glycoprotein N (Gn) from autophagy-dependent breakdown maybe by blocking autophagosome formation (By similarity).  Inhibits host EIF2AK2/PKR dimerization to prevent PKR-induced translational shutdown in cells and thus the activation of the antiviral state (By similarity).  Also displays sequence-unspecific DNA endonuclease activity (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the hantavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host Golgi apparatus, host cis-Golgi network. Note=Internal protein of virus particle.
Protein: MDH_BORPD
Sequence: MSKPAMRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQKALKGVIMELDDCAFPLLQEVTAHSDPRTAFKDADVALLVGARPRGPGMERKDLLSVNAQIFTAQGKALNDVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALSQLAAKSGKAVADIEKLVVWGNHSPTMYPDYRFATVGGQSLAKLINDDAWNRDTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGSNGKWVTMGIPSDGSYGIPEGIIYGVPVTTENGEYKRVEGLEIDAFSRERLDFTLKELLEERDGVKDLLK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: GSHRP_TOBAC
Sequence: ATSLSTPKLSTTLSSPTLHSLLYKHKFSLLSLSNPIKPLHFNFLTHSRSTPSSLSCTRRRFTAPRAESSNGADAPRHYDFDLFTIGAGSGGVRASRFASNFGASVAVCELPFSTISSDSTGGVGGTCVLRGCVPKKLLVYASKYSHEFEESCGFGWNYDVEPRFDWSTLIANKNAELQRLTGIYKNILKNAGVTLIEGRGKVVDPHTVDVDGKLYSAKNILISVGGRPFIPDIPGSEYAIDSDAALDLPTKPNKIAIVGGGYIALEFAGIFNGLKSEVHVFIRQKKVLRGFDEEIRDFVGEQMSLRGIEFHTEESPQAIVKSADGSLSLKTSRGTVEGFSHIMFATGRRPNTKNLGLETVGVKMTKNGAIEVDEYSRTSVPSIWAVGDVTDRINLTPVALMEGGALAKTIFAHEPTKPDYRNVPAAVFSQPPIGQVGLMEEQAIKEFGDVDVYTANFRPLKATISGLPDRVFMKLIVCAKTSKVLGLHMCGDDAPEIVQGFAIAVKAGLTKADFDATVGIHPTSAEEFVTMRTPTRKVRSSPSEGKAEHDIKAAAGV
What is the function of this protein?
Maintains high levels of reduced glutathione in the chloroplast.
What are the official names of this protein?
Glutathione reductase, chloroplastic, GR, GRase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNH3_LISMF
Sequence: MANTVILVDQPTLEKMKQTYLPFSNPKLPPGAVFAAKKPGVSITGYKSRKVMFQGVNGEVEAKKWVATLPESKTKAPSVSKGILPANFASKNVIGSDEVGTGDFFGPITVCAAYVDAEMMPLLKELGVKDSKAMKDPEICRIAEKIMPLVPHSVLLCPNPKYNELQKRGMNQGQMKALLHNRAIENVLKKLAPVKPEAILIDQFAEKNTYYRYLAKEPSIIREDVFFATKAEGLHLSVAAASIIARYKFVQAFDAMSKEVGIPLPKGAGPHVDAVAAEIIERFGLETLTKYTKQHFANTEKALKMVKK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_EHRCJ
Sequence: MPLYEFTFIAQQGLTQYELEGLVKGLSSLLTKNGAELLKYEYWGLLDFAYTIDKMNKGHYCMIYIKATPSSMDEFKRKVRLNEDVLRFLCLKKDKLPKGDSLMIQANQV
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RL16_BRUSI
Sequence: MMQPKRTKFRKQFKGRIHGNSKGGTDLNFGAFGLKALEPERVTARQIEAARRAITRHMKRAGRVWIRIFPDLPVTSKPTEVRMGKGKGSVDYWACRVAPGRVMFELDGVPEDVAREALRLGAAKLPIKTRFIQRIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL9_BRUSU
Sequence: MEVILLERIGRLGQMGDTVKVKDGYARNFLLPQGKALRANEANKKKFEGQRAQLEAQNLERKNEAQAVADKLNGESFIVVRSAGETGQLYGSVSTRDIAEIITADGFTLHRNQVELNHPIKTIGLHEVSVSLHPEVQVKVMVNIARSTEEAERQAKGEDLTSIEAIYGIEEQPLSEEVFDDEDEAEDQA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: HOLB_BACSU
Sequence: MAISWKEMNELQPRVMKLLYNSIEKDRLSHAYLFEGKKGTGKLDAALLLAKSFFCLEGGAEPCESCRNCKRIESGNHPDLHLVQPDGLSIKKAQIQALQEEFSKTGLESHKKLYIISHADQMTANAANSLLKFLEEPNKDTMAVLITEQPQRLLDTIISRCQTLPFQPLQPKAIEDRLIEQDVSPHMARLLANMTNNVAEAVELSRNDEFAESRAKVIKLYEVLHQRKGHAFFFIQDQWMPFFKEKTHQEMGLDMLLLIYRDVLSIQIGNEDKLIYQDLFQSIKQHALQSTQQSVTNQILAVLEAKKRLHSNVNVQGLMEHLVLMLQEG
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.
What are the official names of this protein?
DNA polymerase III subunit delta'.
Protein: FOLQ_LACLM
Sequence: MNEDLISQIKEVVTAENQEKLIKIIQLLESSNYELRGKINPDLQLSASALVFKEDKLFFIEHPYQKELLLPAGHVELKESPLDTAIREFHEETGFFAKKMGKLVDVNLIDIPFNETKNEKKHQHIDFRYLLELEEQEAELAELPFFLLELEEAPEEFKKYYRYKNI
What is the function of this protein?
Probably mediates the removal of pyrophosphate from dihydroneopterin triphosphate (DHNTP), a possible step in the pterin branch of the folate synthesis pathway.
What are the official names of this protein?
Probable DHNTP pyrophosphohydrolase, Dihydroneopterin triphosphate pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: STK3_HUMAN
Sequence: MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVKTSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPFPMSKNVFPDNWKVPQDGDFDFLKNLSLEELQMRLKALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF
What is the function of this protein?
Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation.  Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.  STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.  Phosphorylates NKX2-1 (By similarity).  Phosphorylates NEK2 and plays a role in centrosome disjunction by regulating the localization of NEK2 to centrosome, and its ability to phosphorylate CROCC and CEP250.  In conjunction with SAV1, activates the transcriptional activity of ESR1 through the modulation of its phosphorylation.  Positively regulates RAF1 activation via suppression of the inhibitory phosphorylation of RAF1 on 'Ser-259'.  Phosphorylates MOBKL1A and RASSF2.  Phosphorylates MOBKL1B on 'Thr-74'.  Acts cooperatively with MOBKL1B to activate STK38.
What are the official names of this protein?
Serine/threonine-protein kinase 3, Mammalian STE20-like protein kinase 2, MST-2, STE20-like kinase MST2, Serine/threonine-protein kinase Krs-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The caspase-cleaved form cycles between nucleus and cytoplasm (PubMed:19525978, PubMed:11278283). Phosphorylation at Thr-117 leads to inhibition of nuclear translocation (PubMed:19525978).
Protein: LPXD2_RHOPB
Sequence: MSESGFFLDAVGLSVGDIVALTGATPRDGADLSRAISDLAPLDRAGIADLSFIAETKYAGVLAATQAGAVLTTERFAHLAPESVAVLRIAKPYEAFVAVARRLYPSALRPTSLFGTLGVAPGAVVHPSAKLAAGVTVDPGAVIGPRAEIGKGSLIGANAVIGPHVKIGADCAIGAGCTVTHSEIGDRVIVHPGSQIGQDGFGYISSANGHTKVPQIGRVVIHDDVEIGAGSNIDRGGMRDTVIGQGTKIDNLCQIGHNCVIGRHCIIVAQSGLSGSVTVEDFAVLGARTGVIPHITIGKGAMLASRSTVYSNVPAGAVWGGFPAQSKRQWMREVVALRQLAARDHDGRTAASAEAAAPSSDATGVDQPDQAAS
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: F16PA_CHLPB
Sequence: MNKLITIERHFVEEQKLNPDATGELTDLLYDVAFAAKLVRREVVRAGLVDILGMAGTTNVQGEEVKKLDLFANDKIINAIGQHGRFALMGSEENEGTIIPPKNESGKYVLLFDPLDGSSNIDVNVSVGTIFSIYRLTGDDPSKADINDCLQKGSQQVAAGYVIYGSSVVMVYTTGHGVHGFTYDPTIGEFLLSHENITTPKQGKYYSINEGSRKQFNDSTVNYINYLKEEDAETGRPYSTRYIGSLVADFHRNLLTGGVFVYPATKQHRNGKLRLMYEANPLAFICEQAGGRATNGSERILDIDPSELHQRTPLYIGSEEDVIIAEEFEQGKR
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIAO1_RAT
Sequence: MKDALVLQSRVPAHPDSRCWFLAWNPTGTLLASCGGDRKIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYQEEGDDWVCCATLEGHESTVWSIAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCVCTLSGFHTRTIYDVAWCQLTGALATACGDDAIRVFEEDPGSDPQQPTFSLTAHLRQAHSQDVNCVAWNPKEAGLLASCSDDGEVAFWEYHQPAGL
What is the function of this protein?
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (By similarity).  As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors.  The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins.  CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2 (By similarity).  Seems to specifically modulate the transactivation activity of WT1.  As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (By similarity).
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_XANP2
Sequence: MSGVNEIRSSFIDYFVKEGHEAVASSPLVPQNDPTLMFTNAGMVQFKNVFTGVEKRPYSRAATSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKDRAIELAWNLVTRTFELPRDRLVVTVFSEDEEAYGLWKKIAGLSDDKIIRIPTSDNFWSMGDTGPCGPCSEIFFDHGPNVPGGPPGSPDQDGDRFIEIWNLVFMQFEQLPGGERLALPRPSIDTGMGLERVSAVLQGVHDNYDTDLMRALIAEVAELTSVNPDGPQKASHRVIADHLRASVFLTADGVLPSNEGRGYVLRRIMRRAMRHAQLLGAKDPLMHRLVPVLVREMGRAYPEIVRAESLAEETLLLEETRFRRTLERGLSILEEESTGLTSGGQFPGEVAFKLYDTYGFPLDLTQDALRARGISVDTTAFDAAMARQKAEARASWAGSGEAATDTLWFSVRDEVGATEFLGYETEKAEGVVAALVRDGAVVDSLAAGEKGLVILNQTPFYAESGGQVGDIGRVSGEGGVAAQVVATQKKLGDLFVHEVKVETGTLKRGTALVLEVDHARRAAVRANHSATHLLHEALRRVLGDHVAQKGSLVAPDRLRFDFSHPKPLSGGELAEVETIANRFVLRNEPVETRIMAVDDAITSGARALFGEKYGDEVRVVSMGTDDGNGAPYSVELCGGTHVKRTGDIGLISVLSESAVASGVRRIEALTADAARRHLNAASAALAGTAAVLKAPVAEVEARVATLVEERRRLERELAEARKKLAMGGGGEASGDAVRTVGDIKLLARRVEGIEIKDLKGLVDEGKKQIGSGVVAIVGVTSDGKAGIVVGVTADLIARFDAVALVRVGSEALGGKGGGGRPDMAQAGGPDGAKAEAALDAIAAAMAG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHC1A_ARATH
Sequence: MSSSRNTHWCHRCQRAVRLHGQEPVCFYCGGGFVEELDMAQASPFDMFRSHRGVVERDQTFDLMDAFSVFMRNRLAERSHDREIRGRTISSGPENFPGLAPLLIFGGQVPYRLTGDNAVEALFNGGSPGIGITRGNTGDYFFGPGLEELFEQLSAGTTRRGPPPAPRSAIDALPTIKIAQRHLRSSDSNCPVCKDEFELGSEAKQMPCNHIYHSDCIVPWLVQHNSCPVCRQELPSASGPSSSQNRTTPTRNYRSSSSSSSSNSRENGNERRNPFSSFWPFRSSGSSSSSTQNRGGTRNSDTSDENHNYHQQQHQQSYMGYSGWPFDY
What is the function of this protein?
Probable E3 ubiquitin-protein ligase that may possess E3 ubiquitin ligase activity in vitro.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase RHC1A, RING-H2 finger C1a, RING-H2 zinc finger protein RHC1a, RING-type E3 ubiquitin transferase RHC1A.
Protein: QUEC_ALCBS
Sequence: MKKAVVLLSGGLDSATCLAIARDQGYACHTIAFDYGQRTRSELDAAERVSGVLGALSHRVIELGMGNIGGSALTDHSIEVPENGGDGIPVTYVPARNTVFLSLALGLAEVIDAQAIFIGVNAVDYSGYPDCRPAFIEAFQSMATLATKAGVEGRPMQIETPLMHLSKAQIIQRGVALGLDYGLTVSCYQADDHGNACGKCDSCRLRSQGFEDALVKDPTNYQ
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.