PharMolix/UniProtQA huggingface dataset:
Protein: TON2_ARATH
Sequence: MYSGSSDGESHDTSTQRKIPPASSMLWVRNLRRYIGSGAGLGSEALMELETKRILLEIFKEKQQKSQEAGTIPSFYKKKPEEGSISQRVQKLAKYRFLKKQSDLLLNADDLAAMWVCLRENCVIDDATGAEKMNYEDFCHIASVCTEQIGPKCRRFFSPSNFMKFEKDEAGRIAILPFYLYVMRTVSLTQARIDMSELDEDSDGFLHSDEMESYIGGLIPNLAQLRDMPPAFNQMYCRIASQKFFFFCDPHRRGRACIKKILLSNCLQELMELHQESEEEVTDTEQAENWFSLTSAQRICDMFLALDKDMSGSLCKQELKEYADGTLTEIFIERVFDEHVRRGKIVAGNSREMDFDSFLDFVLALENKDTPEGLTYLFRCLDLQGRGFLTTADIHSLFRDVHQKWIEGGNYELCIEDVRDEIWDMVKPSDPLKITLGDLLGCKQGGTVASMLIDVRGFWAHDNRENLLQEEEEPPEEESQ
What is the function of this protein?
Probable regulatory subunit of type 2A protein phosphatase involved in the control of the dynamic organization of the cortical cytoskeleton.  Plays an important role in the organization of interphase microtubule arrays in part through the regulation of nucleation geometry.  Required for the reorganization of cortical arrays in response to light.
What are the official names of this protein?
Probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2, Protein EMBRYO DEFFECTIVE 40, Protein GORDO, Protein TONNEAU 2.
Protein: NUSB_DEHMC
Sequence: MTTSRRKAREIVLQALYEQDLAGHNAEDVLKRLLTENPQTEENVEFIFRLTNAVVKHKDLLDENIRQFASAWPVEQLSYIDRNVLRLAIFEIIHENDVPVKVAINEAVELAKSFGGNSSARFINGVLSSVSKALADTANQREE
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: TMED5_HUMAN
Sequence: MGDKIWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEIEYQVLDGAGLDIDFHLASPEGKTLVFEQRKSDGVHTVETEVGDYMFCFDNTFSTISEKVIFFELILDNMGEQAQEQEDWKKYITGTDILDMKLEDILESINSIKSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSMVNLVVMVVVSAIQVYMLKSLFEDKRKSRT
What is the function of this protein?
Potential role in vesicular protein trafficking, mainly in the early secretory pathway.  Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly.  Probably not required for COPI-vesicle-mediated retrograde transport.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 5, p24 family protein gamma-2, p24gamma2, p28.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Probably cycles between compartments of the early secretatory pathway.
Protein: MUTL_SHIF8
Sequence: MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASISSVSRLTLTSRTAEQQEAWQAYAEGRDMDVTVKPAAHPVGTTLEVLDLFYNTPARRKFLRTEKTEFSHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGTAFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQLETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAAREPVAPRYSPAPASGSRPAAPWPNAQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLERDGNISLLSLPVAERWLRQAQLTPGEAPVCAQPLLIPLRLKVSGEEKSALEKAQSALAELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLMSEHAQWIARNLMSEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SYDND_ALKEH
Sequence: MRTHYCGHVSETDLDQEVTLCGWAHRRRDHGGVIFIDLRDREGLVQVVFDPDRPETFALAERVRSEFVLKVRGRVRRRPAGTENPDLPTGQVEVLGLELDLLNPAKTPPFQLDEHEQAGEDVRLRYRYVDLRRPEMLQRLRARARITSNLRRFLDEHGFLDIETPMLTRATPEGARDYLVPSRTHPGSFFALPQSPQLFKQLLMMAGMDRYYQIVRCFRDEDLRADRQPEFTQLDIETSFMDEEGIMHLTERMMRRLFADVLQVDLPDPFPRMGYAEAMARFGSDKPDLRIPLELVEVADLMGGVEFKVFAGPAADPRGRVAALHVPGGAGLTRKQIDDYTQFVGRYGAKGLAYIKVNDPAQGREGLQSPILKFLTDEAVDGILRRTEARAGDLIFFGADKAKVVNDALGALRVKLGHDLAMVEDEWRPLWVVDFPMFEYDEKDGRLYALHHPFTAPNVDDPAELADKDPEQLVSRAYDMVLNGTELGGGSVRIHRQDMQQAVFRLLGIDEDEARAKFGFLLDALEYGAPPHGGIAFGLDRLVMLMTGASSIREVMAFPKTQTAACLLTDAPAEVDIAQLQELALRITKPQA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y23K_BPP22
Sequence: MLASLGGLVSCAAKVHFKEEGNAMNELIANHDFDFRQLVTAAEGQPVTDTFQIAKAFGKRHADVLRALKNCHCSEDFRRAHFCVSEKINNLGIFDKKQIYYRMDFSGFVMLVMGFNGAKADAVKEAYINAFNWMSAELRKYSESYEAERNAIMLEYMKEKDVASMSGRLLNRWGKIKKPQLLARIGRLEQHGQTVIPGLTN
What are the official names of this protein?
Uncharacterized 22.8 kDa protein in gp15-gp3 intergenic region, ORF201.
What is the protein family that this protein belongs to?
To H.influenzae HI_1412.
Protein: PAX_I00A1
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVEPEDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPKEAKKQLKKDLKSQGQCAGSLTKAFRRTSPALRILEPMWMDLNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: DUT_ORYSJ
Sequence: MATATNGNASAAAAAADSAVQEPPHKIAKVAPLLKVKKLSENAVLPSRGSALAAGYDLSSAAEVVVPARGKAMVPTDLSIAIPEGTYARVAPRSGLALKHSIDVGAGVIDADYRGPVGVILFNHSDTDFAVKPGDRIAQMIIEVIVTPEVAEVEDLDATVRGEGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP, preventing uracil incorporation into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PSAB_GRATL
Sequence: MATKFPKFSQALAQDPTTRRIWYGIATAHDFESHDGMTEENLYQKIFSSHFGHIAIIFLWTSGNLFHVAWQGNFEQWVAQPMKIKPIAHAIWDPHFGQPAVKAFTKGGASYPVDITFSGVYHWWYTIGMRTNNDLYNGSLFLLILSAIMLFAGWLHLQPKFKPGLSWFKNNESRLNHHLSGLFGLSSLAWTGHLIHVAIPESRGQHVGWDNFTYTLPHPAGLQPFFTGNWSVYASDPDTSNHIFGTSQGAGTAILTFLGGFHPQSQSLWLTDMAHHHLAIAIVFIIAGHMYKTNWGIGHNIKDILDAHRPPSGRLGKGHKGLYATITNSLHMQLGLALASLGVITSLVAQHMYAMPPYAFMAKDFTTQAALYTHHQYIAGFLMVGAFAHGAIFFIRDYDPEENKNNVLFRMLDHKEAIISHLSWVSLFLGFHTLGLYIHNDTMIAFGTPEKQILIEPVFAQWIQASSGKALYGFNTLLSSSSSIATKAGSSVWLPGWLEAINSNKNSLFLAIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLSVFWMLNTIGWVTFYWHWKHMTIWQGNVNQFNESSTYLMGWLRDYLWLNSSPLINGYNPYGMNNLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLVRWKDKPVALSIVQARLVGLVHFSVGYILTYAAFVIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: P3_BPPM2
Sequence: MNTSVPTSVPTNQSVWGNVSTGLDALISGWARVEQIKAAKASTGQGRVEQAMTPELDNGAAVVVEAPKKAAQPSETLVFGVPQKTLLLGFGGLLVLGLVMRGNK
What are the official names of this protein?
Protein P3, Protein III.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Note=Part of the capsid inner membrane. Deeply embedded in the lipid bilayer. About 20% of the molecule extends to the exterior.
Protein: KCTD2_MOUSE
Sequence: MAELHWTRQWRGWEGVAAVRWATAAARAADPPALALRGRHPADTAASPPPPRTAGARARTSGADGRRRGRPLGPAQRGRYLLRDTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELGEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNQDQAEFLCVVSRELNNSTNGIVIEPSEKPRFFRKRALECERTV
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD2.
Protein: MOD21_SCHPO
Sequence: MTMSRADQILQHLLRELIHNDSLVASEWLKHSKKIIQNVPSSTLVFHEMIEHIKGICDKMGIQGREDLEMPLRNACEVLNRQTVSVKQSILHAQILKLFLELSKPPSDIHVPQIPVYKDCNKNEQEAIIQLLTSCEGDHWLMPDWSSMPDDETITEDSEEETFNGNANEITIPANIHIPIIEESDNASNNKLCTLFKKSKQPNLDFLQIKPFMFWDSSLNETVRISERSIIRDSIYMLIGYPSFFFLKNGSKIETRLSLLPKLHHMSEEILRSIMTELADYGSNLEFFRQKLTSPSDSFFKSDDQSTKNEPFLSVVFIYPQIKPHLLSCLKNTHQELIKLETEVYNATKNCTLFQFFQHVKKFVDPLLCFRFAYEKSATNMWDFVKTLEFIYSTRNYSSQMFKLYKASAIAMLLWMVNQASQITSSMTIARPLYNILILCKDFPNNFLEKDNIALQLGSIVFDQSPTLNNLLVEMEILIRSKILKLGKSLDLSFDFQSLMGEFENLIKQQEEAKKSLWSKRFSRFYYGHYVFVNTCHNFFLTLYQSFTEVDENSIFNGVFETLNNDVDDESVIGEKEKLILKQKQKCLSEFFVDDIKKLLNEELLNCQKQELPDVMENTYQISTVSGIKNDPLFTLDQTCNIIAKLADNLIHPSVPIGSSAYRCRRNLADLLFLIMP
What is the function of this protein?
Component of the gamma-tubulin complex that is required for the regulation of both interphase microtubule organization and nucleation, and mitotic bipolar spindles.  Required for correct septation.
What are the official names of this protein?
Gamma-tubulin complex subunit mod21.
Protein: SRB8_EMENI
Sequence: MIPNSSAGGQSWGHPLRNVDNDTARGDTSQAFNRPDIRSEGQQYTPALPRHPGQPAVIDLTSSANDAQEGQPPAKRLKLDITAESSANPASPTPATTGDSRVTPGIANSKPSALSWRGRPVWSFQAMISEVMSGAEATEEDAILAPQGKRPASPPPFPQPSWKGAPPEQFGSNATKASESDSSKKVQTTPFRVEVPSIAPALKGDKVADFAPWIGNHPEDILSEQTVKQGHYDRTQVSQNESNTARPSLYAQLKHRSGLQMLSSVFMAALEKRQNHNTINVPSNFKPPPRVTLTDNKREAWLRDLANPSVPLRRLSRTIPHGIRGKNLLDQCLSKWIPVNRAVWLVKCVGANEIRACKRKGTGGTLVVGSEVKWVRDWTSGVQQFLEGVIGACGSADWKSKMTYATSLTARLFFERLLDHDQYFAWFLTSLEGASLNMVPVWLLMLGIYWDSMLRYRKRGRRLAEVLLGKLHQTTELQRPTLLQPLAERLSCCIRKLVLEHTSSLILPNSWETHRDLILSCLNMKETADKTIFDSLAERNSRIQLPSSRSDSTRQSAHQRVIQLFDSIQSSQDIASTSVACLNALEDRQTLVIKLLEWSATSFRSGLHRVYTAARLLRKWKISGVDIDTYIISFLSTVQDLAQLDMDNVYHIISELVRSQTFSVSRYLQWLMAKGVARKSSGTSGEVLAADARLLTQLPMSRSPEHVRNLRLTLLARAGVSVDEESSTIKCLKSSISQRLPNIFEVEASNSKHINFSKHDLTWAVKSEVSMWIRQGVVKHLKDTTRISALTPGEFYCVREILERFGDCSILADVLKQAIECDDNIILASVSDTVNYHFDALSMIGATSDLFRGLVGSYARLKRSGNLSLDFVFSLIELGLRLPDESGTVYLLRQDLARIESKSALAAPSPLSDHIPTTFNEVDASFQERLEQLLSCGNGLDESTMGAIISSLTKILTDGGGAAKVSAKDACRYLAYLRPFNPKYLDGMLVRYVYGLLKSSSRPTMSQVLSPLIGVGCVTIHSFVLLVNKLSASAQTTGAIANPDSLRLDILELLLPQEESSADMVTYRFRLAQQEFLVKYPEETLNIISDAIPLFDADFHDANLGSRRPDLPACTVVLLRTLLAQNSSLVLKYCMQKLDGHSSFTTVLGKAVDILLGLDPEDEMEPSSQAERVILMNNDFSLPYCQLKLKLLFNAKAGNEVKNHIVDVMFKAAVTDSRSKRSHWVGLVSLMDQEAARQIRERAEGCFFSVAMFDESMDDTSLPSGASSLSSIESAKLYLNIIEKLAYSIPQAGVQSIPPLLVERLDLLLQKLIIMQINSNSVAASSSGSTIVSKINFERALAFWFSALLRLIVLHRAAFNVPPASGSKVDSLREQTRLLVSILCISLARLPENILRLFPAADYFPHTIQSHNFRPCPGILLQTHALDVAASLIDSFPDEARHQCVRFLRERCPPFLKFQNDRRFLYLLGPMTDTTIPSSQLSASISSPAAGGSTPTPIPSGTLSGGHSSQATQQMAALTGPFSGLSENTKLVADRLRIQNGGRINGPYPVRPWELLEDAAPILGVNDTAVSLKLFDARRVRA
What is the function of this protein?
Component of the srb8-11 complex.  The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH10_RICPR
Sequence: MSFKPLHDRIAIKPIENEEKTKGGIIIPDTAKEKPMQGEIVAVGNGVLNKNGEIHPLELKVGDKVLYGKWAGTEIEIKGEKLIVMKESDVFGIIN
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_METTH
Sequence: MMVAMIIENPLRGSYIERPNRFTVAVYVDGERRLAHLRDPGRLRELLIPGNDVILRKASSGNRKTEFDVIALRRDDEWVLVNSGFHSDLAASIIESSAVDEFRGFRIEKRECSFGRSRIDFLLASENERMLVEVKGCTLVRENLALFPDAPTERGRRHVEELERALSEGYHSSVLFLVFGRSARFFSPNHEMDPEFSSALRRAHEAGVNVIPYTLATDINEKVLVYPLRRIAVRWPGESP
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: AB28B_ARATH
Sequence: MASATTLLFHHGSTRVLVARRRCQASVLRPYGGLKPFLSFCSLPNSTAPFRDSLRAKSDGLARAYVTGAPPIVEEPDPKIEESKSEAESKDLISWGLLWSLMSKHKLRLSVCLLTLLGCSTCTLSMPVFSGRFFEVLIGVRPEPLWRLLSKIAVLYSLEPIFTIAFVTNMTAIWENVMAILRAQIFRRVLIQKAEFFDKYKVGELTGLLTSDLGALNSIVNDNISRDRGFRAFTEVFGTICILFTLSPQLAPVLGLLMLAVSVLVAVYKRSTVPVYKSHGLAQATMSDCVSETFSAIRTVRSFSGEKRQMSIFGSQILAYKLSGLKLGTFKSINESITRVAVYISLLALYCLGGSKVKTGELAVGTVVSFIGYTFTLTFAVQGLVNTFGDLRGTFAAIDRINSILNAVDIDEALAYGLERDIHTKKVQDENLKLFLSAGPNVNIRHLDKYYMSNLKSTNNLRTLTWAGDVCLDDVHFAYPLRPDVKVLDGLSLTLNSGTVTALVGSSGAGKSTIVQLLARFYEPTQGRITVGGEDVRMFDKSEWAKVVSIVNQEPVLFSLSVAENIAYGLPNEHVSKDDIIKAAKAANAHDFIISLPQGYDTLVGERGGLLSGGQRQRVAIARSLLKNAPILILDEATSALDAVSERLVQSALNRLMKDRTTLVIAHRLSTVQSANQIAVCSDGKIIELGTHSELVAQKGSYASLVGTQRLAFE
What are the official names of this protein?
ABC transporter B family member 28, ABC transporter ABCB.28, AtABCB28, Non-intrinsic ABC protein 8, TAP-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLO2_XANOM
Sequence: MRLIALPAFDDNYIWALVAADGRAIIVDPGQAAPVIATAEREGLVPSAILLTHHHGDHIDGVAELQQRWPGLELFSPADERIPTTAHHVSHGERLSLLAVDFQVIEVPGHTRTHIAFVTDRHLFSGDTLFSLGCGRMFEGTAPQMFDSLQRLACLPGETLVCCGHEYTLANAAFALHVDSTNAALQRRQQEAQAMRHAARPTLPISLKSELATNPFLRTNRPEIRAVVAARAAGALSSEVDVFAELRRWKDEFCL
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: GCSH_PROM0
Sequence: MSYKFPDNLNYADTHEYVLEENGLLKIGVSEFAIDQLGDIVFVELADEGATLEKGETFGTIESVKAVEEVYLPFSGEIVSVNESVIENPELLQSDPIGDGWLVILKPESKASIADLMTSEEYQSKVVPK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: DNCH_PROMT
Sequence: MIDRFLDKRNPREWLCLKRTVRFGETDAAGVVHFLELFRWCHETWEESLEKYGIALKDIFPTNEINTSQLDIALPVVHCEANYFQPLYVGDTINIELETEKINESSFVLRFKFKKNGEQIGSTNIKHVSINPITRKKCALSKQINLWLHESSSNF
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Protein: TBA_CHLVU
Sequence: MREVISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKHVPRCVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTAVVEPYNSVLSTHSLLEHTDVSVMLDNEAVYDICRRSLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYSPVISAEKAYHEQLSVAEITNSAFEPASMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAESAEADGEDEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CADH4_HUMAN
Sequence: MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFSSCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLLVAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMYGGGEED
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  May play an important role in retinal development.
What are the official names of this protein?
Cadherin-4, Retinal cadherin, R-CAD, R-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS13_LEVBA
Sequence: MPRIAGVDLPRDKRIAYGLTYIFGIGINTAHKIVADAGVPEDVRVRDLTPDQEDKVRAEVDKYKVEGDLRREVSLNIKNLQEIGSYRGMRHRRGLPVRGQHTKNNARTRKGKAVSIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: UREG_POLAQ
Sequence: MRTKKNPPLRVGIGGPVGSGKTTLLEMLCKAMRAKYDLVVITNDIYTKEDQRLLTVAGALEPERIMGVETGGCPHTAIREDASINLEAVDRMQKQFPDVDIIFIESGGDNLAATFSPELSDLTIYVIDVAGGEKIPRKGGPGITRSDLLVINKTDLAPYVGASLPIMESDAKKMRGERPFIMGSVKLGDGLNEIIKFIEQKGLLVS
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_CAMJD
Sequence: MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPVKDTARVIGAMVDFIMMRVNKHENLLEFARYSKAPVINALSELYHPTQVLGDLLTIKEWNKIQNGIAKVAFIGDSNNMCNSWLIAAAILGFEFSIAIPKNYEINPEIWDFAMKQALISGAKISLSHDKFKALKDKDVVITDTWVSMGEENEKERKIKEFEEFMIDEKAMSVANEDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_RALSO
Sequence: MAKKIIGFIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAQTQGMEPGLPVPVVITAFADKSFTFVMKSPPATVLIKKAAGVQKGSAKPHTDKVGKITRAQAEEIAKAKNADLTAADLDAAVRTIAGSARSMGITVEGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: TOLB_ECOLI
Sequence: MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQWAGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVTFESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity (PubMed:17233825).  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane (PubMed:19696740).  The Tol-Pal system is also required for polar localization of chemoreceptors clusters (PubMed:24720726).  The system also appears to be required for the activity of several outer membrane-localized enzymes with cell wall remodeling activity (PubMed:32152098).  Is involved in the uptake of some colicins A (PubMed:2687247, PubMed:7929011, PubMed:11994151).
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm. Note=Partially associated with the outer membrane through a specific interaction with Pal (PubMed:7744736). Accumulates at cell constriction sites. Recruitment to the division site is dependent on FtsN activity (PubMed:17233825).