PharMolix/UniProtQA huggingface dataset:
Protein: NDK_ACAM1
Sequence: MERTFLAVKPDGVQRGLVGEIISRYEAKGFTLVGLKLMVVSRELAEQHYGEHKEKPFFSGLVDFITSGPVVAMVWEGKGVVAAARKIIGATNPLGSEPGTIRGDFGIDIGRNIIHGSDAVETAQREISLWFKSEELADWSPTLTSWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S27A2_HUMAN
Sequence: MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL
What is the function of this protein?
Exhibits long-chain fatty acids (LCFA) transport activity but lacks acyl CoA synthetase towards very long-chain fatty acids.
What are the official names of this protein?
Long-chain fatty acid transport protein 2, Arachidonate--CoA ligase, Fatty acid transport protein 2, FATP-2, Fatty-acid-coenzyme A ligase, very long-chain 1, Long-chain-fatty-acid--CoA ligase, Phytanate--CoA ligase, Solute carrier family 27 member 2, THCA-CoA ligase, Very long-chain acyl-CoA synthetase, VLACS, VLCS, Very long-chain-fatty-acid-CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: CIROP_HUMAN
Sequence: MLLLLLLLLLLPPLVLRVAASRCLHDETQKSVSLLRPPFSQLPSKSRSSSLTLPSSRDPQPLRIQSCYLGDHISDGAWDPEGEGMRGGSRALAAVREATQRIQAVLAVQGPLLLSRDPAQYCHAVWGDPDSPNYHRCSLLNPGYKGESCLGAKIPDTHLRGYALWPEQGPPQLVQPDGPGVQNTDFLLYVRVAHTSKCHQETVSLCCPGWSTAAQSQLTAALTSWAQRRGFVMLPRLCLKLLGSSNLPTLASQSIRITGPSVIAYAACCQLDSEDRPLAGTIVYCAQHLTSPSLSHSDIVMATLHELLHALGFSGQLFKKWRDCPSGFSVRENCSTRQLVTRQDEWGQLLLTTPAVSLSLAKHLGVSGASLGVPLEEEEGLLSSHWEARLLQGSLMTATFDGAQRTRLDPITLAAFKDSGWYQVNHSAAEELLWGQGSGPEFGLVTTCGTGSSDFFCTGSGLGCHYLHLDKGSCSSDPMLEGCRMYKPLANGSECWKKENGFPAGVDNPHGEIYHPQSRCFFANLTSQLLPGDKPRHPSLTPHLKEAELMGRCYLHQCTGRGAYKVQVEGSPWVPCLPGKVIQIPGYYGLLFCPRGRLCQTNEDINAVTSPPVSLSTPDPLFQLSLELAGPPGHSLGKEQQEGLAEAVLEALASKGGTGRCYFHGPSITTSLVFTVHMWKSPGCQGPSVATLHKALTLTLQKKPLEVYHGGANFTTQPSKLLVTSDHNPSMTHLRLSMGLCLMLLILVGVMGTTAYQKRATLPVRPSASYHSPELHSTRVPVRGIREV
What is the function of this protein?
Putative metalloproteinase that plays a role in left-right patterning process.
What are the official names of this protein?
Ciliated left-right organizer metallopeptidase, Leishmanolysin-like peptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TYRR_SALTI
Sequence: MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFAELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHLALSALLEALPEPVLSLDMKSKVEMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLMEITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVEQARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELFGHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVRVICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAATVAVGEDAMEGSLDDITSRFERSVLTQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQKKGEE
What is the function of this protein?
Dual transcriptional regulator of the TyrR regulon, which includes a number of genes coding for proteins involved in the biosynthesis or transport of the three aromatic amino acids, phenylalanine, tyrosine and tryptophan.  These three aromatic amino acids act as effectors which bind to the TyrR protein to form an active regulatory protein.  Acts by binding specifically to TyrR boxes in the promoter region of the target genes.
What are the official names of this protein?
HTH-type transcriptional regulatory protein TyrR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_NITOC
Sequence: MTDGLERLCRKLGYRFAEPALLRHAITHRSATKENNERLEFLGDSILNFLIADFLYSGFPRAQEGELSRLRATLVKGETLAELARELEIGDHLILGLGELKSGGYRRTSILADAFEAVIGAVYLDGGLEACRKLVSSLYRDRLETLTNEALLNLKDPKTRLQEYLQARQFPLPDYRVSAVSGEAHDQVFQVECTLNNTFPSVIGIGRSRRKAEQDAATRALALLLAENEDMNV
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_METM6
Sequence: MDVVFALGGSVLMPKEGASTENIQNYAEAFKKLKEMGHRVSVVVGGGNTARQYISVAREFTNESFCDEIGILATRMNSMLLISALGKDAVKHVPENFKDAELILNMDKILVMGGTHPAHTTDAVSATLAEFIDADLLVIATNVDGVYDKDPRCNEDAVKLDKINTKELLEITGSASMSAGSSGVVDPLASKIIDRAKLKTIVVKGIPEEILASVTENHNGTTITP
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCPI_MELCP
Sequence: CDLACSLIYAPVCGSDGKTYPSECSMEATACIDEVVITKVHDGPCETKCSAACTKEYNPQCGTDGVTYANPCTLEYAKCKSDGEITFDHAGPCKPKCPTVCTLEYNPQCGTDGRTYGNPCQLKVAECESDGRITLDHPGECDACSLKKVVGPCRGAFRRYYFDSVSGKCEEFVYGGCGGNDNNFKTLDACQKRCMEE
What is the function of this protein?
Inhibits trypsin, kallikrein, subtilisin Carlsberg, human leukocyte elastase, porcine pancreatic elastase and chymotrypsin.  Two domains are for the inhibition of chymotrypsin.
What are the official names of this protein?
Four-domain proteases inhibitor, McaPI.
Protein: RIMO_RHOPB
Sequence: MNQAAAPKVSFVSLGCPKALVDSERIITRLRAEGYELARKHDGADLVIVNTCGFLDSAKKESLGAIGEAMAANGKVIVTGCMGAEPEQIEAAYPNLLSITGPQQYESVLDAVHRALPPLHNPHLDLVPAQGIKLTPRHYAYLKISEGCNNRCSFCIIPKLRGDLVSRPAGEVLREAEKLVKAGVKELLVVSQDTSAYGVDLKYAESPWQDRNVRARFYDLAKELGELGAWVRLQYVYPYPHVDEVIGLMAQGKVLPYLDIPFQHASPEVLKQMKRPAAQDKTLARIKQWREICPELTLRSTFIVGFPGETDSDFAYLLDWLEQAEIDRVGAFKYEAVRGATSNALPDQVSDEVKTERWNALMARQQKISARRLKRKVGTRQQVIIDEVGPTVSKGRSKADAPQIDGSVYLTSRRPLRVGEIVTAKIERADAYDLHGSVAGF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_CUPNH
Sequence: MSILSFLLGEKKKSASVAKERLQIILAHERTGHSAPADYLPALQRELVAVISKYVKIGDQDLRVSLERQDNLEVLEVKIEIPQN
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: T2_MOUSE
Sequence: MQRGREREAESQRVRESERQRGREAERQRERQRGREAERQRGRERGREAEREAERQRGRERQRGRGEAERQRGRERGREVERHRRGREAERQRGREREAERQRGREAEREAERQRERQRERQRGREAERQRGREAERQRGREAEKQRGERQRGREVEAEAEGRGRGMRQEAEATEQGQGQRQRQR
What are the official names of this protein?
Octapeptide-repeat protein T2.
Protein: ACKA_GEOSW
Sequence: MSKILAINAGSSSLKFQLFEMPSETVLTKGIVERIGFDDAIFTITVNGEKIQEVTAIPNHAVAVKMLLDKLISHGIIRSFDEIDGIGHRVVHGGEKFSDSVLITDEVLKQIEEVSELAPLHNPANIVGIKAFQEVLPNVPAVAVFDTAFHQTMPEQSFLYSLPYEYYTKFGIRKYGFHGTSHKYVTQRAAELLGRPIEQLRLISCHLGNGASIAAVEGGKSIDTSMGFTPLAGVAMGTRSGNIDPALIPYIMQKTGMTADEVLEVLNKKSGMLGISGISSDLRDLEKAAAEGNKRAELALEVFANRIHKYIGSYAARMCGVDAIIFTAGIGENSEVIRAKVLRGLEFMGVYWDPALNKVRGKEAFISYPHSPVKVLVIPTNEEVMIARDVVRLANIG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBC5_YEAST
Sequence: MSSSKRIAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTKIYHPNINSSGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAQIYKTDKAKYEATAKEWTKKYAV
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:19920177, PubMed:2154373).  Mediates the selective degradation of short-lived and abnormal proteins (PubMed:2154373).  The RSP5-UBA1-UBC5 ubiquitin ligase complex ubiquitinates RPO21 forming 'Lys-63'-linked polyubiquitin chains (PubMed:19920177).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2-16 kDa, E2 ubiquitin-conjugating enzyme 5, Ubiquitin carrier protein, Ubiquitin-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: SN_PIG
Sequence: MDFLLLLLLLASSALAGLASWTVSRPETVQGIKGSCLIIPCTFGFPANVEVPHGITAIWYYDYSGKRLVVSHSRNPKVVENHFQGRALLLGQAEQRTCSLLLKDLQPQDSGSYNFRFEISEGNRWSDVKGTVVTVTEVPSVPTIALPAKLHEGMEVDFNCSTPYVCPTEPVNLQWQGQDPTRSVTSHLQKLEPSGTSHMETLHMALSWQDHGRILSCQVSAAERRMQKEIHLQVQHAPKGVEILFSHSGRNVLPGDLVTLSCQVNSSNPQVSSVQWVKDGTKLKDQKRVLQLRRAAWADAGVYTCQAGNAVGSSVSPPVSLHVFMAEVQVSPVGSILENQTVTLACNTPKEAPSELRYSWCKNHALLEGSHSRTLRLHSVTRADSGFYFCEVQNARGRERSPPVSVVVSHPPLTPDLTAFPETQAGLVGILQCSVVSEPPATLVLSHGGLISASTSGEGDHSPRFSVASAPNSLRLEIQDLGPTDSGEYMCSASSSLGNASSTLDFHANAARLLISPAAEVVEGQAVTLSCRSSLSLMPDTRFSWYLNGALILEGPSSSLLLPAASSTDAGSYHCRAQNSHSTSGPSPPAVLTVLRAPRQPVFTAQLDPDTAGAGAGRQGLLLCRVDSDPPAQLQLLHRGRVVASSLSWGGGCCTCGGCFQRMKVTKAPNLLRVEIRDPALEDEGVYLCEASSALGNASASATLDAQATVLVITPSHTLQEGIEANLTCNVSREASGPANFSWFRDGALWAQGPLDTVTLLPVSRTDAALYACRIVTEAGAGLSTPVALNVLYPPDPPKLSALLDVDQGHTAVFVCTVDSHPLAQLALFRGEHLLAASSALRLPPRGRLQAKASANSLQLEVRDLSLGDSGSYHCEATNILGSANTSLTFQVRGAWVRVSPSPELQEGQAVVLSCQVPIGVLEGTSYRWYRDGQPLQESTSATLRFAAITLSQAGAYHCQAQASGSATTDLAAPVSLHVTYAPRQATLTTLMDSGLGRLGLLLCRVNSDPPAQLRLLHGSRLVASTLQGVEELAGSSPRLQVATAPNTLRLEIHNAVLEDEGVYTCEATNTLGQTLASAALDAQAMRVQVWPNATVQEGQLVNLTRLVWTTHLAQLTYTWYRDQQQLPGAAHSILLPNVTVTDAASYRCGILIPGQALRLSRPVALDVLYAPRRLRLTHLLESRGGQLAVVLCTVDSRPAAQLTLSHAGRLLASSTAASVPNTLRLELWEPRPSDEGLYSCSARSPLGQANTSLELRLEGVQVALAPSATVPEGAPVTVTCEDPAARPPTLYVWYHNSRWLQEGSAASLSFPAATRAHAGAYTCQVQDAQGTRISQPAALHILYAPRDAVLSSFWDSRASPMAVVQCTVDSEPPAEMTLSHDGKVLATSQGVHGLAVGTGHVQVARNALQLRVQNVPSRDKDTYVCMDRNSLGSVSTMGQLQPEGVHVVAEPGLDVPEGTALNLSCRLPSGPGHIGNSTFAWFRNGRQLHTESVPTFTFTHVARAQAGLYHCQAELPAGAATSAPVLLRVLYPPKTPTMTVFVEPEGGIQGILDCRVDSEPLASLTLHLGSRLVASSQPQAAPAKPHIRVSASPNALRVDMEELKPSDQGEYVCSASNALGSASAATYFGTRALHRLHLFQHLLWFLGLLASLLFLLLGLGVWYAWRRGNFHKLRMGEYSVEMVSRKETTQMSTDQEEVTGIGDDAGSVNQAAFDPAHLCENTQSVKSTV
What is the function of this protein?
(Microbial infection) Facilitates porcine reproductive and respiratory syndrome virus (PRRSV) infection via inhibition of type I IFN transcription.
What are the official names of this protein?
Sialoadhesin, pSn, Sialic acid-binding Ig-like lectin 1, Siglec-1, p210.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ERA_CROS5
Sequence: MNENLDLGNLSTIPIAPEGFKSGFVGIIGRPNVGKSTLMNQLIGQKIAITSPVSQTTRNRLQGILTTDKAQIIFVDTPGIHKPHHTLGKIIVKNAKTAINSVDIILLVVDSSVKSGGGDRYIIDLLKTVNQPVILGLNKSDQQTEKYQEIDESYANLIQDHNWPMIKFSALTGDGVETLQNTLIEQLEPGPYYYPPDLITDQPERFIMAELIREQILQLTRQEVPHSVAVTIEKVEESPKITKIFAAINVERSSQKGIIIGQKGNMLKAIGTTAREQIQKLIAGEVFLKLFVKVEPQWRQSNLRLAEFGYRVEE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: CLPX_DESPS
Sequence: MDEIGKNDMENSCSFCGRSQEEVDKLIAGPDVFICNECIELCNEIVQEDIVGSKDDGQEVLPGLVPKDVKAHLDDYVIGQAYAKKVLAVAVHNHYKRIDAPVELLDDSVELQKSNIILLGPTGSGKTLVAQTLAKILNVPFSVADATTLTEAGYVGDDVENILVSLLQAADYDVEKAQRGIIYIDEIDKIARKSDSASLTRDVSGEGVQQALLKIIEGTVASVPPKGGRKHPQQELVKIDTTNILFICGGAFVGLGRVVKRRAGKKSIGFSADLSADKRSESELLEAVRPEDLLKFGLIPELVGRLPVIASLRELSEDDLVRILREPKNALTRQFEKLFQFEGVKLTFTEGSLAAVAKKAIARKSGARGLRSVLEEAMLDIMYDIPSLSNVQECIVNEQVITDGEYPVLLYGEEEKSLT
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: NTPPB_SHEFN
Sequence: MKFNLVLASTSPFRQQLLQKLMLPFTCVNPDIDETPIKDETALALVKRLAEQKALAGANLIDETSVPQIIIGSDQVALINGQIIGKPYTVDNAIAQLSSASGQSITFYTGLAVFNNANQQMISCVEPFTVHFKHLSTAQIRYYVDAEQPLYCAGSFKCEGLGIALFNRLEGDDPNSLIGLPLIKLIDLLSQHGVDILSQAPECSIN
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FER1_DESAF
Sequence: MARKFYVDQDECIACESCVEIAPGAFAMDPEIEKAYVKDVEGASQEEVEEAMDTCPVQCIHWEDE
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-1, Ferredoxin I, FdI.
Protein: MBP_LEUER
Sequence: MASATTSDHAKQAGGAHSRQRDSGLLDQLGKLFGQEGSRKVPEKGKEPATRSVLMAPTTHKAHQGARRQTDDSPVVHFFKNMMSPKKAPVQQKAKSGASRAITKFIWGTDGQRAHYGAAGSSKSKDGFRGRKDGSGTLSSFFKMGKKGEGSPARR
What is the function of this protein?
This protein may function to maintain proper structure of myelin.
What are the official names of this protein?
Myelin basic protein, MBP.
What is the protein family that this protein belongs to?
Belongs to the myelin basic protein family.
What are the subcellular locations of this protein?
Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.
Protein: PMGT2_CHICK
Sequence: MNIAAVFNALLVSVLATVLWKYIKLREHAFMVEEELVLMRQSQELSQVQIDYHAALQTLLEDGTRMVCTGRMHTDRICRFESLCYSTEAEEFIYFHSNSSVMLPNLGSRRFQPALLDLSSVEDHNTQYFNFVELPAAALKFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPIYYTMQQFTDLDPETRLFFMEGWSEGVHFDLYKLLSNKQPLLREQLKTLGRLLCFTKSYVGLSKITTWYQYGFVQPQGPKANILVSGNEIRQFTKFMMQKLNVSLEESSSEEYIVVFSRTINRLILNEAELILALAQEFQMKTITVSLEEHSFSDIVRLISNASMLVSMHGAQLVMSLFLPRGATVVELFPYAINPEHYTPYKTLATLPGMDLQYIAWQNTAREDTVTYPDRPWDQGGIAHLDKAEQERIIKSTEVPRHLCCRNPEWLFRAYQDTKVDIPSLIHVIRQTVKSKPGPKKKWSGSLYPGKVRDARCQASVQGTSEARLSVSWQVPWNLKYLKVREVKYEVWIQEQGENTYMPYILSHQNHTFSENIKPFTIYLVWIRCIFNKNLLGPFADVLLCST
What is the function of this protein?
O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein.  Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity).
What are the official names of this protein?
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, POMGnT2, Extracellular O-linked N-acetylglucosamine transferase-like, Glycosyltransferase-like domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 61 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: DDLA_CLOPE
Sequence: MKVGVIMGGISSEREISIQSGNSVVHALDKDKYEAIPIVLNEKEDLIEKVKGIDFALLALHGKFGEDGTVQSVLKTLGIPFSGCGPLSSAICMDKDMTKRILAFGNVRTARWEMVSSVDEIDYEKIENLGYPVFVKPNNGGSSVATTLVESKEAVKDAVLEALKYDTEVMIEEYIKGDEITCPIIDGKMLPVLAIKPKGKFFDIASKYGDGGADEFIVELNEDLHKEVEKMALETYKLLKCDVYARVDMLVKDNIPYVLEVNTLPGMTKNSLFPKSAAGINMSFEELLDTIIEKSLKVNRE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase A, D-Ala-D-Ala ligase A, D-alanylalanine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_STRSV
Sequence: MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYINIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKERKGEYLGATVQVIPHITDALKDKIKRAARTTDSDVIITEVGGTVGDIESLPFLEALRQMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEKPAGQNIKNKLAQFCDVAPEAVIESLDVEHLYQIPLDLQAQKMDQIVCDHLKLDVPAADMTEWSAMVEKVMSLEKQVRIALVGKYVELPDAYISVVEALKHAGYANDAEVKIDWIDANQVTVENAAELLGSADGIIVPGGFGQRGTEGKIQTIRYAREQDVPMLGVCLGMQLTCVEFARHVLGLADANSAELNPDTPFPIIDLMRDQIDVEDLGGTLRLGLYPSKLKSGSKAAAAYDHQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQYHPELSSRPNRPEGLYTAFVTAAVEKSSDR
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NCAP_I73A0
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYKRRDGKWMRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVVPRGQLSTRGVQIASNENMETMDSSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPVVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: TPBG_MOUSE
Sequence: MPGAGSRGPSAGDGRLRLARLALVLLGWVSASAPSSSVPSSSTSPAAFLASGSAQPPPAERCPAACECSEAARTVKCVNRNLLEVPADLPPYVRNLFLTGNQMTVLPAGAFARQPPLADLEALNLSGNHLKEVCAGAFEHLPGLRRLDLSHNPLTNLSAFAFAGSNASVSAPSPLEELILNHIVPPEDQRQNGSFEGMVAFEGMVAAALRSGLALRGLTRLELASNHFLFLPRDLLAQLPSLRYLDLRNNSLVSLTYASFRNLTHLESLHLEDNALKVLHNSTLAEWHGLAHVKVFLDNNPWVCDCYMADMVAWLKETEVVPDKARLTCAFPEKMRNRGLLDLNSSDLDCDAVLPQSLQTSYVFLGIVLALIGAIFLLVLYLNRKGIKKWMHNIRDACRDHMEGYHYRYEINADPRLTNLSSNSDV
What is the function of this protein?
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
What are the official names of this protein?
Trophoblast glycoprotein, 5T4 oncofetal trophoblast glycoprotein, 5T4 oncotrophoblast glycoprotein, Wnt-activated inhibitory factor 1, WAIF1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RUTA_VARPS
Sequence: MNVGIFIPIGNNGWLLSENAPQYKPSFELNKEITLTAERYGVDFVLSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTTKIKLFATAASLVMPPAIVARMASTIDSISNGRFGLNLVTGWQRPEYSQMGMWPGDQFFGTRYQYLSEYIQVLRELWGKGQSDFKGDHFQMDDCRLSPQPQADMKVICAGQSDAGMDFSARYADYNFCFGKGVNTPKAFAPAAEKLIEATRKTGRHVTTYVLMMVIADETDEAARAKWEHYKAGADHEAIAWLGQQGAADTRSGADTNVRQMADPTSAVNINMGTLVGSYATVARLLDEMAEVPGTEGVLLTFDDFVQGVAAFGERIQPLMKSRVHVQSPVPSQAEAERLAA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: POBB_PSEOL
Sequence: MSAAATMAPVSLRIHAIAYGADDVLLFDLRAPARDGLAPFDAGAHIDLRLPRGITRSYSLLNDPAERHRYVIGVKREPESRGGSAWLHADARVGALIEVDGPSNHFALDESAPHAVFIAGGIGITPLWSMVQRLEHLGTPWTLHYRARSRRGAALLDELAGHGDRVHLSFSDEGAPSLDLAAIVAAAPEGAHFYCCGPVPMLEAFEAACVGLDPARVHLEYFAAKEAPATEGGFVVHLARSGRTIPIAAGCTILDALQAGGVAVPSSCQQGVCGICETAVLAGVPDHRDLVLSDQERAAGRTMMICCSGSKTAELTLDL
What is the function of this protein?
Degrades exclusively diarylether compounds having carboxyl groups in the 3- or 4-position.  Yields a hemiacetal that spontaneously hydrolyzes to phenol and protocatechuate.
What are the official names of this protein?
Phenoxybenzoate dioxygenase subunit beta, 4-carboxydiphenyl ether;phenoxybenzoate dioxygenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the PDR/VanB family.
Protein: KTHY_ECO24
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.