PharMolix/UniProtQA huggingface dataset:
Protein: ELP3_YEAST
Sequence: MARHGKGPKTNKKKLAPEKERFIQCCADITLELTDSLTSGTTREINLNGLITKYSKKYKLKQQPRLTDIINSIPDQYKKYLLPKLKAKPVRTASGIAVVAVMCKPHRCPHIAYTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYEQARGRVEQLKQLGHSIDKVEYVLMGGTFMSLPKEYREDFIVKLHNALSGFNGNDIDEAILYSQQSLTKCVGITIETRPDYCTQTHLDDMLKYGCTRLEIGVQSLYEDVARDTNRGHTVRSVCETFAVSKDAGYKVVSHMMPDLPNVGMERDIEQFKEYFENPDFRTDGLKIYPTLVIRGTGLYELWKTGRYKSYSANALVDLVARILALVPPWTRIYRVQRDIPMPLVTSGVDNGNLRELALARMKDLGTTCRDVRTREVGIQEVHHKVQPDQVELIRRDYYANGGWETFLSYEDPKKDILIGLLRLRKASKKYTYRKEFTSQRTSIVRELHVYGSVVPLHSRDPRKFQHQGFGTLLMEEAERIAKEEHGSEKISVISGVGVRNYYGKLGYELDGPYMSKRI
What is the function of this protein?
Catalytic tRNA acetyltransferase subunit of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:15769872, PubMed:17018299, PubMed:18755837, PubMed:21912530, PubMed:31309145).  In the elongator complex, acts as a tRNA uridine(34) acetyltransferase, which mediates formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).  The complex functions as a gamma-toxin target (TOT); disruption of the complex confers resistance to Kluyveromyces lactis toxin zymocin (pGKL1 killer toxin) (PubMed:11296232).  May also be involved in sensitivity to Pichia inositovora toxin (PubMed:13680368).  Independently, ELP3 may be involved in polarized exocytosis (PubMed:15780940).
What are the official names of this protein?
Elongator complex protein 3, Gamma-toxin target 3, tRNA uridine(34) acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ELP3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1543_MYCTO
Sequence: MNLGDLTNFVEKPLAAVSNIVNTPNSAGRYRPFYLRNLLDAVQGRNLNDAVKGKVVLITGGSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAIAVMADQVLGDLGGVDILINNAGRSIRRSLELSYDRIHDYQRTMQLNYLGAVQLILKFIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAETVHDNVRFTTVHMALVRTPMISPTTIYDKFPTLTPDQAAGVITDAIVHRPRRASSPFGQFAAVADAVNPAVMDRVRNRAFNMFGDSSAAKGSESQTDTSELDKRSETFVRATRGIHW
What are the official names of this protein?
Uncharacterized oxidoreductase MT1595.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: AAS_SALPC
Sequence: MLFGFFRNLFRVLYRVRVTGDVQALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLDPTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRIQLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTKTLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQVKQQPEDEAIILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKGPNIMNGYLRVEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSAEKMHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACAP2_RABIT
Sequence: MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCLANKQFMNGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALAKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCVPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIKAKYVERKFVDKYSVSSSPPEQEKKVVSKDSEEKRLSIPKLGPGDQVRTSIQSSVKSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSVFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
What are the official names of this protein?
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, Centaurin-beta-2, Cnt-b2.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein.
Protein: KCY_CHLMU
Sequence: MIITIDGPAGTGKSTLAKALAKTLQFNYCNTGAMYRTLAYARLQPDWQEVPLEDFLASPPFSFSFSKDAPLQAFYENRPLTSELISQEVANFASIFSKEPKVRAYMQTLQKRYASVGSCVFEGRDMGSKVFPHAEVKIFLTAEPEIRAKRRLKDLPEGSLSQEALTAELIARDQADQQRELDPLVIPADALVIDSSDLTISQILEKIVPLIHSRLA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1389_STAAS
Sequence: MVKTVYVTGYKSFELNIFKDDAPEVHYLKQFIKHKIEQLLDEGLEWVLIQGQMGIELWTAEVVIELQRTYDSLKFAVITPFQGHTEKWNEHNQSKYANIIKHADYVDSIFHTSYQGPFQFKQADQFMLEHSDQTLLIYDEEQEASPKFFKQMLVDFMDKTNYTCDIVTFDELTAFINDLQWSEDQSF
What are the official names of this protein?
UPF0398 protein SAS1389.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: PRMA_CLOB1
Sequence: MDKEWLEVCIYTSSEALEAISGILYNTGVKGVSIEDPKDIEFKRKHPGDWDYFDETLLKVKDTAIVKGYYKEDDKFNEYLDYIKKSVSNLDQFGIDKGEGLVEVHKVNEEDWENNWKKYYKPTKVSNKIVIKPIWENYDKKQEEIIVELDPGMAFGTGTHETTRMCINALEKYIKEDRTVFDIGCGSGILSIAAAKLGAKHVIGVDLDPVAVKSSKENIKYNNLDNIEILEGNLMEVVEGRANIVVANIIADVIIFLTEGVKAFIEKGGYFIASGIINSRKEDVIKKLEETGFIIEEVREEGEWACIVSKIN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDI_DROME
Sequence: MKFLICALFLAASYVAASAEAEVKVEEGVLVATVDNFKQLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDSFVFGVSSNADVIAKYEAKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGGHIEKYVDPLKEIAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFLDANGEVADSEPVEETEEEEEAPKKDEL
What is the function of this protein?
Participates in the folding of proteins containing disulfide bonds.
What are the official names of this protein?
Protein disulfide-isomerase, PDI, dPDI.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: NRDR_THEPX
Sequence: MKCPYCGYPDSKVIDSRPTDDNTSIRRRRECLKCGKRFTTYEKVEQLPILVIKKDNRREVYDRDKILKGMIKACEKRPVPIKVLEEITDEIDKRIINSMEREITSTEIGEMVMEKLKNVDEVAYVRFASVYRQFKDINTFMDELKKLLKESETKKENA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: YDL14_YEAST
Sequence: MNFCFFTLFPSSITELSQMNLVSQTHFCYIGRITTHT
What are the official names of this protein?
Putative uncharacterized protein YDL114W-A.
Protein: EFG1P_CANAL
Sequence: MPKTVKNPKNNKSRSRGAPIQVAESIGSGSAKIKKKIRDIERLIKKNPNLPADKKIEYDRALKGLKVELQNSQVQNKAKVLAKKYHMVRFFERKKAVRKLKNLRKEFERISQTGIRKDIKKARKQLRHGEIDLAYVILFPKTEKYISLYPSPNDEDQTDPNVIKGLKITEERRREFRKYIEKLMEEGKLPFSIDDALQGKNIRLDNDKTQKAVLTEEIDAPEQKQDEQQEEQDDFFE
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein EFG1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LSPA_SERMA
Sequence: MLIIGKKLSPYALLSISGLLAASDQAVKWLVQQSMAYGEYVSVTPFFNWVHLWNTGAAFSLFANGGGWQRYFFIGIAVVVSIFLIKLILENRHKGEAIAYSLILGGAMGNLIDRVFRGYVVDSFDFYWRDWHWPAFNLADIAIVLGALLFVSSSLLGKKANTNAEPDGSD
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECA_STAA1
Sequence: MDNDRQKALDTVIKNMEKSFGKGAVMKLGDNIGRRVSTTSTGSVTLDNALGVGGYPKGRIIEIYGPESSGKTTVALHAIAEVQSNGGVAAFIDAEHALDPEYAQALGVDIDNLYLSQPDHGEQGLEIAEAFVRSGAVDIVVVDSVAALTPKAEIEGEMGDTHVGLQARLMSQALRKLSGAISKSNTTAIFINQIREKVGVMFGNPETTPGGRALKFYSSVRLEVRRAEQLKQGQEIVGNRTKIKVVKNKVAPPFRVAEVDIMYGQGISKEGELIDLGVENDIVDKSGAWYSYNGERMGQGKENVKMYLKENPQIKEEIDRKLREKLGISDGDVEETEDAPKSLFDEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REV_SIVMK
Sequence: MSSHEREEELRKRLRLIHLLHQTIDSYPTGPGTANQRRQRRRRWRRRWQQLLALADRIYSFPDPPTDTPLDLAIQQLQNLAIESIPDPPTNTPEALCDPTKDSRSPQD
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rev, Regulator of expression of viral proteins.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: VNS3_AQRVG
Sequence: MATADTTHTMLSALFDALLQTNDTFTTVRNRVRVMKRALDQHVEDPFAHECSLSQMPRPVIPAPTPAPTNRIQPEGIITMWATAHFEIHGGGQRLATSERAPRIIMHVSPTTVRLEIPLTTYIPEKRMRTGSKLRIAILKGTTHNAETGKFDEVAWQRLVLVLTKKTPHPSTLVTNYWTCEEQGLIRPVKSTGSNMIAATPLNSLTLELPGPDADSQYEQLTCMPMSCVFE
What are the official names of this protein?
Non-structural 3, NS3, NS26.
What is the protein family that this protein belongs to?
Belongs to the aquareoviridae NS3 protein family.
Protein: LPRG_MYCS2
Sequence: MQTRPRFAVQSLFAILATAAALVAGCSSSSETSDAPLPDGAALLQESASKTKTQQSVHLLLTVQGKVDGLPVEKLDGDLTNAPAVAAEGTADLIAFGQKIADAKFVIADGNLYAALTPGDPLSNYGAAANIYDVSAILNPDTGLANVLANFSDATADGRESINGTEAVRVKGNVSADAVNKIAPALKADGPVPGTAWITEDDHTLLQAQLEPTPGNSVTMTLSDWGKQVNVTKPAA
What is the function of this protein?
Probably helps membrane protein MSMEG_3069/MSMEI_2992 (P55) transport triacylglycerides (TAG) across the inner cell membrane into the periplasm and probably ultimately to the outer membrane (By similarity).  Required for MSMEG_3069/MSMEI_2992 export activity.  Export of ethidium bromide by MSMEG_3069/MSMEI_2992 can be complemented by the equivalent operon from M. tuberculosis (lprG-Rv1410c) (PubMed:18156250).
What are the official names of this protein?
Lipoarabinomannan carrier protein LprG, 27 kDa lipoprotein, Antigen P27, Lipoprotein LprG, Triacylated glycolipid carrier LprG, Triacylglyceride transfer protein LprG.
What is the protein family that this protein belongs to?
Belongs to the LppX/LprAFG lipoprotein family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: CDA3_CRYNB
Sequence: MYGHLSLSTLSLLAVVAAAPFHESWLQPRDSDVSQLFRRGAPDPKASDYLSYYPSPGSTPNVSTIPQAWLDKLATVQLPNVSVATANDGRPTYPNNENDGDSEICSFTDQCYVEDDLYSPPGEKVWALSFDDGPTDVSPALYDYLAQNNISSSATHFMIGGNIITSPQSVLIAIEAGGHLAVHTWSHPYMTTLTNEQVVAELGWTMQALSDLNGGRIPLYWRPPYGDVDNRVRAIAKGVFGLVTVLWDSDTNDWAISDQPDQYSVASVEAYFDTLVTGNRTQGLLLLEHELDNNTVEVFETEYPKAVANGWSVKNVADAFSMKWYLNSGKGNDDVVTTMSVAGTLTTAKPTHTSTSVASATATSSASVTDSAGVSIASAASSQESSSWPIANRPSLFVIACGLALAAIMV
What is the function of this protein?
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate (By similarity).  Chitosan is required to anchor melanin to the cell wall, for maintenance of cell wall integrity, and for proper cytokinesis (By similarity).  Chitosan offers an advantage during infection as it is less readily detected than chitin by host immunosurveillance mechanisms (By similarity).
What are the official names of this protein?
Chitin deacetylase 3.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: YIDC_SOLM1
Sequence: MENKRVILAVALSLAVLVGWNFLFPPAKQAPKPDAAVSQQDAPAQSSPAAPAAKAETLAAFAPTPGKRITIDTPLYTAVLNSTGGVLEQFALKNYRETIKPDSPLVNLIDDKAKAKAPLGIILNGSPTWQNVDWSAEGGDLKLEAGAAGTVVLAGRMGDVVVKRELTFSGDSYIIDEKFSLSNNGGAPLRNRLSLTVAVDRLSAADDSYNPTQAAFYGASGLDLESGDKKLAEGVAPEKPMEWGAVMSNYFLVGIVPEAADLRGKAKLEDGVFRVALDKDGLEVPAGGRSDLSIAYFLGPKVPKYLEMAPHKLVASIDYGWFDFVAKPLIKLLHFFYDYVGNYGVAIILLTILIKLIFWPLSQKSYKSMDQMKKLQPLLTQLREKYKDDRQKMNEEMMQLYKTYKVNPAGGCLPMIVQIPVFFGLYQALLHSIELRHASFITHLPFTNMIWLADLSAKDPFYITPLIMGATMFLQQKMTPAPGDPTQAKVMLFMPVIFTFMFLNFPSGLVVYWLVNNVISIAQQGWMLNKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATP6_NEUCR
Sequence: MSTLSFNNISTEVLSPLNQFEIRDLLSIDALGNLHISITNIGFYLTIGAFFFLVINLLSINYNRLVSNSWSISQESLYATIHSIVTSQINPRNGQIYFPFIYTLFIFILINNLIGMVPYSFASTSHFVVTFALSFTIVLGATILGFQKHGLEFFSLLVPAGCPLALLPLLVLIEFISYLARNISLGLRLAANILSGHMLLHILAGFTYNIMTSGIIFFFLGLIPLAFIIAFSGLELGIAFIQAQVFVVLTSGYIKDALDLH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PARP2_CAEEL
Sequence: MSIINDENGRGYKVHLCKTNIAQNNNKFYDMELLDEGGDFIVKLINGRIGYRGVTQLKDFDDLDRAKKFFESKFYEKTHLHWEERDDEPVPNKYAVVELATNARQTEKEVKKEEPEPEPKVDEKNTRGRKKRGIVKEKKEIKKEEEPVEEVNEKLKELMKCICDEDVHLGLLKQLKFNEAFGRPIDCLSLAQLTTGYEILSKIEESIGGKSARRSTRGRPRVADRVLAVKSDGPSLHDINKYYSLIPHSFGFCVPPKIDSHAKIQAERELLDALKGSIEASLELKDLKKTASSKDIYQRLYERLPCHLEPVSEEIAGKIGDCLAMRGPTHCYKLSLIDAFELKDPNEIPTEAPVEVQEVPKKRGRKSTKTAAPTVPPPTTKRLLWHGTRVTNVFSILMNGLQFPVGDRCGLMFGNGVYFANVPTKSANYCCPEASKRVFMLLCEVETANPLVLYESEIDADEKMEKAKKTSVYAAGKHTPRDTVEINGIPAFKSNLETIEEETRLLYDEYVMFNKEHFKIKYVVEVKVDRLTAKEMMA
What is the function of this protein?
Poly[ADP-ribose] polymerase modifies various nuclear proteins by poly(ADP-ribosyl)ation, a post-translational modification synthesized after DNA damage that appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks and programmed cell death.
What are the official names of this protein?
Poly [ADP-ribose] polymerase 2, Poly ADP-ribose metabolism enzyme 2, Protein poly-ADP-ribosyltransferase parp-2.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RH10_ORYSI
Sequence: MAKKKDVEVEELDEEVVAAAAAPAADGGEEQEAEPPARRPSTFAELGVVPELVAACDAMGWKEPTRIQAEAIPHALEGRDLIGLGQTGSGKTGAFALPIIQALLKQDKPQALFACVLSPTRELAFQIGQQFEALGSAIGLSCTVLVGGVDRVQQAVSLAKRPHIVVGTPGRLLDHLTDTKGFSLNKLKYLVLDEADKLLNVEFQKALDDILNVIPKERRTFLFSATMTNKVSKLQRACLRNPVKVEVASKYSTVDTLRQEFYFVPADYKDCFLVHVLNELPGSMIMIFVRTCESTRLLALTLRNLRFKAISISGQMSQDKRLGALNRFKTKDCNILICTDVASRGLDIQGVDVVINYDIPMNSKDYVHRVGRTARAGNTGYAVSLVNQYEAMWFKMIEKLLGYEIPDRKVDNAEIMILRERISDSKRIALTTMKEGGGHKKKRRKNEDDEEEEERNAPVSRKSKSFNKSRRR
What is the function of this protein?
Has ATP-dependent RNA helicase activity in vitro.  Acts as a thermosensitive RNA chaperone required for normal processing of pre-rRNA intermediates.  Required for normal cell division at high temperatures.  Required for a primary metabolism adaptation to high temperatures to support thermotolerant growth by regulating gene expression.  Partially rescues the yeast rRNA helicase RRP3 mutant which has repressed cell proliferation at 38 degrees Celsius.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 10, DEAD-box RNA helicase TOGR1, Protein THERMOTOLERANT GROWTH REQUIRED1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Localization is not affected by temperature.
Protein: MCA3A_DANRE
Sequence: MGDGGVNAVGEGVNQSHMLFDRFVQATTCKGTLKAFQELCDFLELKPNEYRVFYHKLKSKLNYWKAKALWAKLDKRASHKEYKKGRACANTKCLIIGAGPCGLRTAIELGFLGAKVVLLEKRDAFSRNNVLHLWPFTIQDLRGLGAKKFYGKFCAGAIDHISIRQLQLMLLKVALLLGIEIHVNVEFKGLIEPPEDQENERIGWRAEVHPRTHPVNELEFDVIIGADGRRNTLSGFRRKEFRGKLAIAITANFINRNTTAEAKVEEISGVAFIFNQKFFQDLREATGIDLENIVYYKDDTHYFVMTAKKQSLLEKGVILHDYADTEMLLSRANVDQKALLSYAREAADFSTNHQLPKLDFAINHYGQPDVAMFDFTCMYASENAALVRQRNGHKLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSWAHGSSPLEVLAERESIYRLLPQTTPENVSKNFSQYSVDPTTRYPNISLHQVRPNQVRHLLDTGETRDLRVDLENVVNSSTPKLTRNESIVRSSKLLNWCQRQTEGYRGVSVSDLTTSWKSGLALCALIHRYRPDLIDFESLDEKDVEKNNQLAFDVAEREFGISPIMTGKEMSVVVEPDKLSMVMYLSQFYEMFKDTVPPGENQNLSPEEKAALIASTKSPISFLSKLGQSIAISRKRNPKDKKEKELDGLGKRRKTSQAGQSEDEELQRANRDDRPSIATALAERKIDSAAAANNNNKVKSMATQLLAKFEENAPTQSTGLKRQGSFRKEFPQNIGGSDVCFFCRKRVYVMERLSAEGKFFHRSCFKCDYCGTTLRLSSYAFDVEDGKFYCKPHYCYRLSGVAQRKRPAPAAAPANAKEPQVLAVSPNTVDAPGQAITTQTPAERRPSETEVNGVTEPSVAKRLKGTPERIELENYRLSMMREEELEEVPEETLAEHNLSSVLDKATDIEEGSSSSESDMEEEDEDAEAAGPSDLGGVPWKEAVELHAKLKGESDPGADDDGLHDGDGEMDEDEEEEEDEEDEDEEEEEESSEEPCEEDDDPEAEAGSPDFEPGTEIDQEDIPSDAEAEARSRCIDEVVTLPVDNDKTESQGQVFNTAEKTSANPRELIVDVVLSPIQKPALPIEEVHEVSPVVLVKSPGARFFPEPYLPDKVKQNIPPPQSPDVKTPHSPVAQIIALSPICSQPVPQPGTASPKSPVQPQPCACSPTGNPLSPICTQSQPCNEPPSPLSTSSPVRTQPVPAVTSTPLAKPASENRTNEHLKDSTPELKKTDLIEEFWLKSAEIRKSLGLTPLERSKTAVEKSIVKTPTPESSSPKSYTPEDLSEEQKPTFTGRSIIRRINITLEGQVISPVEPKSNGSEKKDLSSSSGLGLNGSVTTSQTAASDSYNNSDSTMLTPPSSPPPPPPREEPACLQNKKSQVSWDNLLEGTEEPKSETMPIKPRTPVSPPQPKQKPVTAPVPTPRTNPPVVMRVKEPNKPRREEVRKSFVECVDEIPFADDVEDTYDDRTPDASGLEKFYTPPTSKVNRDKPPLHLALAMENGKPNIPGVSRTAKGSQHFSPEAKEIAEERMRAREKSVKSQALKDAMAKQLTKMKDSEVAKGAVAKVAWDIPETKGKSKKQSKAQKDSAVKALESKKQADTLPDRFFSTPSSKALDSSVTSSESSTGGKSKKRSSLFSPRKNKKEKKAKNERLSSTEETPPKHKSLWKAVFSGYKKDKKKKDDKSCPSTPSSSTTGDSGKKKDSPLDRSSDLRLRRNLSFSEDSDLSCDDVLERSSQKSKGDSVYVPHALAFKRSYATKKTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQMIQRQLEQVEEKQRQLEERGVAVEKALRGEADYWGESNYSEILDLHLGGMGKKDDPKLMQEWFKLVQEKNALVRYESELMIFARELELEDRQSRLQQELRERMAIDDHLKTEEELAEEKQILNEMLEVVEQRDSLVALLEEQRLREKEEDKDLEAVMLSKGFNLNWA
What is the function of this protein?
Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin.  Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization.  Involved in exocytic vesicles tethering and fusion: the monooxygenase activity is required for this process (By similarity).
What are the official names of this protein?
Protein-methionine sulfoxide oxidase mical3a, Molecule interacting with CasL protein 3A, MICAL-3A.
What is the protein family that this protein belongs to?
Belongs to the Mical family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Mainly localizes in the nucleus.
Protein: TRPD_MOOTA
Sequence: MLKAQISKVVAGQHLSEAEAAEAMDIIMAGEATPAQIAAFLTALRLKGEMVDEITGFARSMRRRAIPLTTSHPVFVDTCGTGGDGRQTFNISTTAAFVVAGAGVAVAKHGNRSVSSRCGSADMLEALGIKVDLPPDAVARCLDEVGMAFLFAPVFHGAMKYAAGPRREIGIRTAFNLLGPLTNPAGAPCQLVGVYDPDLTETVAAVLGRLGSRRAYVVHGSDGLDEVTITGPSKITCLDKGAIRTYTFTPEDVGLPRANLADLAGGTATDNAAIARAVLSGTRGPARDVVLINAAFALLAAGAADTLQQALALAESSIDSGAAAAKLQAMVAWVESWAA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: YBWL_CAEEL
Sequence: MGSISAIHHIEFIVSNALQSAYWYCSGFGFEKFAEKITDESTSIALRNGTARVIITSYNSQNIYTDQLIKHGDFIKDVSFRVDNLDAVLQNLVENDIKVIQQSEVSTKDGLVRTATLLSEGGDVTHTLFELGEFKGNFLPFFTPISNFELFENIEKMPAILMDHVVQNYPIGEMEAAADWYFKTMRLKRFWSVDDKVATSEFSAMTAWLLVNDDHTVQVTLAEGVKGRKGKSQIEEFINYHGGSGVQHFALLVEDIISAVQIMKSRSVEFLTIPSQYYDNLEERLSKTNLIVKEDLKMIRELNILMDFDENGYLLQIFSKPLQDRPTLFIEIIQRANFKGFGAGNFKALFDAVEREQEKRGTLF
What are the official names of this protein?
Putative protein C31H2.4.
What is the protein family that this protein belongs to?
Belongs to the 4HPPD family.
Protein: RL14_SHEDO
Sequence: MIQMQSTLDVACNSGARRVQCIKVLGGSHRRYAGIGDIIKVSVKEAIPRAKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNANLAPIGTRIFGPVTRELRTEQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.