PharMolix/UniProtQA huggingface dataset:
Protein: NIFH3_AZOVI
Sequence: MTRKVAIYGKGGIGKSTTTQNTAAALAYFHDKKVFTHGCDPKADSTRLILGGKPEETLMDMVRDKGAEKITNDDVIKKGFLDIQCVESGGPEPGVGCAGRGVITAIDLMEENGAYTDDLDFVFFDDLGDVVCGGFAMPIRDGKAQEVYIVASGEMMAIYAANNICKGLVKYAKQSAVGLGGIICNSRKVDGERESVEEFTAAIGTKMIHFVPRDNIVQKAEFNKKTVTEFAPEENQAKEYGELARKIIENDEFVIPKPLTMDQLEDMVVKYGIAD
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.
What are the official names of this protein?
Nitrogenase iron protein 3, Nitrogenase Fe protein 3, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: PSB28_GUITH
Sequence: MAVIQFIQGVNEDVIPDVRLTRSRDGSTGTATFRFANPKVLEAQSSVKGNITGMYLIDEEGQLVTRDVNARFVNGKPQGIEAVYIMQSKEDWDRFMRFMERYSEDNGLSFTKANNS
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: YO48_BPP22
Sequence: MPKQLSPDQDKLHKNILRDRFLSSFKQPGRFRAELEKVKLILKRKGHE
What are the official names of this protein?
Uncharacterized 5.8 kDa protein, ORF48.
Protein: ALB1_KLULA
Sequence: MPSKNSINRPKQKVNLNRKVHQRAAKRDAMEKKGLLAPARSSGTSKSGQLKSIPLDLYKGEHSTSGALTTKTLSKKRAKKIERNLKYVEQRKLLVDLQSQSEENGGMQIDAPVVKKEKETKKGQLEKMREAISTVLEDIQSQGLSLQTGSGTTLGGQYFL
What is the function of this protein?
Involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.  Accompanies the pre-60S particles to the cytoplasm (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein ALB1.
What is the protein family that this protein belongs to?
Belongs to the ALB1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SSPP_BACCR
Sequence: MSHTMGKNNREAKEKKGQPEPLSGSHKVKNRNHSRQKHHAHHDM
What are the official names of this protein?
Small, acid-soluble spore protein P, SASP P.
What is the protein family that this protein belongs to?
Belongs to the SspP family.
What are the subcellular locations of this protein?
Spore core.
Protein: RL32_COXBU
Sequence: MAVQKSRKTRSRRGMRRSHDALRGAMLSKDPTTGETHLRHHISPEGYYKGRQILTPKESYEDEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: STS1_PARBP
Sequence: MNSLLATPPVPPHFYEHVRLSPSRSMSSANSSGNRKRKAEDDNPSDHDTRMSASPSNSPALAPRPLPTARQIKRPRPNISGRPLPLSRLLETLDTDALRSVLRSMCNRHPELETEVVHTAPRPSVSSALQVLSNYESTLQSSFPLGGNSSSDYAYNRVRQHITNLLDALNDFTPHFLPPNESQVSTALSYLDGATEILHRLPRWDTPQHNLEKDVAYEEIAKAWIVVIREAGKRGGGIQLQYGGWDLKLSKHNQTAGGKLQDAINVLSSSLGWMGGHQDSSASQGGDPSSIRHQLLSGTYGSSSPLKVSKW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DDL_CLOBK
Sequence: MKIGVIMGGISTEREVSLNSGREVIKYLELLEHEIIPIIIDKKEDVMEKAKGIDFAFLALHGKFGEDGTVQSVLQTLDIPYSGCGPLTSAICMDKDMTKKILKYANINTADWVNVSSAENIDYEAIEKIGYPVFVKPNSGGSSVATNLVKDKEGIKEAVELALKYDKEVMIENYTKGEEITCCMLNGKMLPVLAIRPHAEFFDYTAKYADGGSDEVVIELEENLHKKVEEMALACWKELKCEVYVRVDMIVKDGIPYVLELNTLPGMTKNSLFPKSANAVGISFAELLNSIVKYSLEVER
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM2_SOYBN
Sequence: MASSIPNAPSAFNSQSYVGLRAPLRTFNFSSPQAAKIPRSQRLFVVRASDSEFEAAVVAGKVPPAPPVRPRPAAPVGTPVVPSLPLHRRPRRNRKSPALRSAFQETSISPANFVYPLFIHEGEEDTPIGAMPGCYRLGWRHGLVEEVAKARDVGVNSVVLFPKIPDALKSPTGDEAYNENGLVPRTIRLLKDKYPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQAQAGADVVSPSDMMDGRVGALRAALDAEGFQHVSIMSYTAKYASSFYGPFREALDSNPRFGDKKTYQMNPANYREALTEMREDESEGADILLVKPGLPYLDIIRLLRDNSPLPIAAYQVSGEYAMIKAAGALKMIDEEKVMMESLMCLRRAGADIILTYSALQAARCLCGEKR
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, chloroplastic, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TCPR_VIBC3
Sequence: MTSIWLHESDFRYVNLDVERYQKKYRLTLTNGNKYVFIKDKEDISDVNPFIPYILMEEGMNNVLVKSDDYKDILIYQGVNIQCLDFLNDNDISVEKLVDFETVELKADELNKIKARRLDAQLIEDEVKNNKVFIIGFIAIVIISIGVFWLM
What is the function of this protein?
Involved in TCP pilus biogenesis.
What are the official names of this protein?
Toxin coregulated pilus biosynthesis protein R, TCP pilus biosynthesis protein TcpR.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: OBG_MALP2
Sequence: MLIDKCTLFLRAGNGGNGVISWRKEAHYPEGGPWGGDGGKGGDVYIIGDHNLNSLIDLRYKKKIEAEDGENGKTKLATGKNGNDIYIKVPVGTTITNSITNEVIVDILVTGQKYLICKGGMGGKGNAYFKSSKNRIPNLCENGELGETIEAQFELKYIADVGLLGLPNAGKSTLVNSLSNTNLKTANYMFTTLSPSLGVVNFEDEHLVFADIPGIIEDASNGSGLGLDFLKHIERCHFLIHLISVANIDTENPFKDYLTIVEELKKYNKEILKRKIFIVLNKIDENDSKDNINLFLKEFKKISNKKVYQISGFFKENTNELLKDIFKDYKKHKEQWERELEEKINSYSLVKVEKEQEDIVTYEKDENRIWVVSSKRIAYWFNRIPFNTDENVTRFMQKIKMDEIEQTLKDKGAKIGDSFRIQDVMFEIN
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_SULIN
Sequence: MVTIVLNKYKLLDKIHIGQQKLEDLLFNLKSEVKPIDENNIEIEINADRLDLLSSDGIARAIKGLLEKELGEAKYNVTDTEYTLIVDNVRTRPYALAAIVYNAKIDLEELIQFQEKLHGTIGRKRKKVAIGIHDLRKVDSKTIEYKEVPLSYKFVPLYGNKELTISEILEKTEQGKLYGNISIANGVSPAIVQDDGEVLSIPPIINSNKTRLDENTKDFFIDVTGTSFEAVAQTLDIIVSNLAEAGGTIGRVKVLKSANSSQLSSPLFLHKIQNVREEYVKKILGIKTSKEEICKHVMRMRMNCDIENGVIRVTVPQYRVDILNEIDVVEDIAMSIGYNNLEPSKYISTNYGSYDYMTLLERKIRELGIGAGYVEISNFVLIKDEKLFSNKYVKILNPVTEEYNAVRDSLIPGLLDFLSKNQHAKFPIRVFETGDVVVYDSSTDTGFRNDKRAAYAIMDNKVSYEDIQAPIHYILKSLGLEVNYKEENNNIFIEGRSASIFYENEKMGVIGEVNPDVLIRFGIEYPAVIAELYISEIGKRLTNQR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF8B_XENLA
Sequence: MADGGSGMCWCLRRCGKNQEVLLLPDGEEVTMGRGLGVTYQLKPTLCPLMISRTHCLFKQNARDEWTVTDNKSLNGVWRNKERLEPHKAYTLSEGTLIQLGVPPPNMESAEFEYILVREHLDKVSGSLIRPLPGKTKATRTKRKFPSEDADASGNEGPSNFSIPKFCRVSRDGEDSAKSLRTSHKQPKASGVEPELNDSVETDTVSPTQQQCCRSTLQLSRVRETMEEIRRLNVQIQEKQIKMQEKLNHPQESQLGSNSYLVVQKELQALRNQLSNEQEQHLQSVKELKEIFQEEQQSMGSQKQAEEEHLKEQLAQALQEHTQLMQELNRNKNDFEQIIQAKNKELQETKEEKEKVCAQKEEVLNHMNDVLDNELQCIICSEHFIEAVTLNCAHSFCSYCIKSWRKRKEECPICRQEILSETRSLVLDNCIDSMVDKLSPEMKNRRAALILERKEMVQAEESNPVLVVSDSSSFLSDTFYISSSSSDSDELGSDFWMVNEEEEYEESLFGCGTDELDSSDFESDDDDSFLIV
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.  Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated mdc1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of tp53bp1 and brca1 ionizing radiation-induced foci (IRIF).  H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates.  Also catalyzes the formation of 'Lys-48'-linked polyubiquitin chains, leading to degradation of substrate proteins.  In addition to its function in damage signaling, also plays a role in higher-order chromatin structure by mediating extensive chromatin decondensation.
What are the official names of this protein?
E3 ubiquitin-protein ligase rnf8-B, RING finger protein 8-B, RING-type E3 ubiquitin transferase rnf8-B.
What is the protein family that this protein belongs to?
Belongs to the RNF8 family.
What are the subcellular locations of this protein?
Nucleus. Note=Following DNA double-strand breaks, recruited to the sites of damage.
Protein: SYS2_METJA
Sequence: MKLTFDLDGKIIFSKELSEEAKNAVEEVLKNADSIFLKGVPKGKENEASKIKSYEFEGNILKLKIASGTYTRAHEGLIRLRKPLAEKLGRNFRIGVRGIEIDNYVITIETDEDKAKKLEGIKVPECEAKVEGNKIILTFKDIGESELKRNIIDRAIKFVKTELEKEEEDLTFKVCKIPPGTIVSEYKAKRKITFDKDPTDVAEKLGWVKKFPGRGQWFYTPPITALFRALEELIVEEVVKKIGFQECLFPKLIPLEIMYKMRYLEGLPEGMYYVCPPKREPELFKEFVNEMMIKKEIPIEKLKNLLRDPGYVLAPAQCEPFYQFFEGEVIDVDKPIMFFDRSGWTYRWEGGGARGLDRVNEFLRVECVWIGSPEFVEETRDKTLKYAEKLAEKLDLEYWVEVGDDPFYLEGRKKEDRGIEFPDVPKYEMRLWLPHIKDERKGVAVTSANVHGTHFVEGFRIKDYKGRRVWTGCTGYGITRWVVGYLAQYGFNFDDWHPIIKKKIKKLPEVPQLITWPKKDE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Type-2 serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_VIBC3
Sequence: MHFHFSKMHGLGNDFMVVDCITQNVFFSPELIRRLADRHTGVGFDQLLVVEAPYDPESDFHYRIFNADGSEVEQCGNGARCFARFVRMKGLTNKYTIHVSTKKGKMVLNVEEEDLITVNMGVPEFEPNKIPFRAKQSEKTYILRVGEHTLFCGAVSMGNPHVVTVVDDIRTAAVETLGPLLESHERFPERVNAGFMQVVSRDEINLRVYERGAGETQACGSGACAAVAVGILQGLLDEQVRVHLPGGELEIHWQGPGKPLYMTGPATHIYDGQISC
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_PHYMT
Sequence: MANIKQQIKRNKTNEKRRLKNVSFKSSVKTAIKKLNKAIENKNKSEALLLLNLSYKKLDKGISKKVYSKNFVSRHKSNLSKLVNNIN
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: GEFE_DICDI
Sequence: MDHTECNNRIEYLQNKVLELESLNENLKGQLEYFQTKFLESNLNSEGKDISSCLTEIYNSLSLDNNNNNSNSNSNSNNNSSNSNNNSYSNFNSNNNTTNNTKVIKNRNFKINLTNSNSTNSSPYIFGNNKDNSNNSNNSNNNNSNTELSNDHLSLEDNIATTNTTTTTTINTSNSNNSNNNNNNNNNNNNNNNNNNNNNNKPTSNRPPVAPRSFIRSNSDTFITPPGSPTSSRNSPTNKSSPQFLSPLSKSPLSQSTQSTTVSSPSPSWTTTVPQSKMRSETIVQSKSPYSPDTNISNKLINELASNIGAPNSNGSESPSKNSPRSLNSNNNNSSATTSITTPPTTSTPTPTTSTTTTTTTERRPEDRRSKTSPFPNVGTTTPPLSNSAHLVRTQSASGANAVKPQSQLSTSCTVNMIGGGGTPRSNNSSNGSLYHSMSSNGLIENLSTSSSLSLSSTSPSPNNSQQNLTNPFEIGADDELEVLDDPRLVMVKTENGFIVKGGTIEKLVNRLIAKHDPDFTSAFLLTHKSFTTSIELLDLLIEFYVNNKDSSSINSNSSSSSSSAVASSSFSNINCNISDLSSSTSSTNSLLINSITNSPIINSNNQNNQNNNNNNNNNNNNNNNQLEINGDKKKKAIRLKITNVIKSWVDKHYYDFSEDKQLTLKLDQFITNHIMFDMDKIGFNLKRLLTNDRVVPVPTFTQGPPTPIPPKMKSNGSEINFKDLDPTEIARQLTLYESDLFRKIGAKECLGQAWNKDGKEENAPNIVSFIKRFNQVSSWVATEIVRQEKLKDRVSYIKRFILVAQECRKLNNFNATMEILSGLQNSSVYRLRKTWERVESKPLLKNTLDELMSLMSSGANYKNYIQELHNIHPPCIPYLGVYLTHLTFIEDGMKNVLTTTTATTTNTTTTTTTTTTTTTTNTTTSNNNNQQQLNGANRSFDDVIINFEKCRKISVVIREIKQYQQQQYHLHTEEFTLRYLSNLPSIQTQKSMYKLSLICEPKEKETSSFDSGYGSVSDRPSKKEFSVTSLLNSFKS
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP (By similarity).  Seems to play a role in chemotaxis.
What are the official names of this protein?
Ras guanine nucleotide exchange factor E, RasGEF domain-containing protein E.
Protein: CAIA_ECO8A
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLLPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANP7_ZOAAM
Sequence: SQSVVATRLIPMNTALTPAMMEGKVTNPIGIPFAEMSQIVGKQVNRIVAKGQTLMPNMVKTYAA
What is the function of this protein?
Contributes to protect fish blood from freezing at subzero sea water temperatures.  Lowers the blood freezing point.  Binds to nascent ice crystals and prevents further growth (By similarity).
What are the official names of this protein?
Ice-structuring protein SP4(HPLC 7), ISP SP4(HPLC 7), Antifreeze protein SP4(HPLC 7).
What is the protein family that this protein belongs to?
Belongs to the type-III AFP family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRK_BACHK
Sequence: MMQKQNMIVVNQKEIAKNIYELVLQGTLVQQMNEPGQFVHIKVAEGIAPLLRRPISICNVDQEKNEFTMLYRAEGQGTKTLATRKQGEMVDVLGPLGHGFPVEEAEAGQTALLVGGGIGVPPLYELSQRLVAKGVRVIHILGFQTKDVVFYEEKFAELGDTYVATVDGTHGTKGFVTDVIDHYGIDFDILYSCGPLAMLRALEGRYKEKKAYISLEERMGCGIGACFACVCHLQEDPSGHSYKKVCSDGPVFPIGEVVL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: ZN365_MOUSE
Sequence: MQQTTFEESRYHWQDSLENVAVCLPFRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLLPSLKDTELLRSSELPKQGKVLRGHAKVTKQKSSYVNLYSISHGHSKDTKPFEMVAERPVSYVQTYTAVDIRADSLDAPCASPGLPTQDTKAAFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFAQLTQKKQEVQRRERALNKQVDVAVEMIAVLKQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFSCDTSEHMLTDIPSNRKPRCLSRGHQHSVCNHPEMRAHFHLKGRSYLKKAKDERAGMQPAKAIHEPAESPREFFRPAKKGEHLGLSRKGNFRPKMAKKKPTAIVNII
What is the function of this protein?
Contributes to genomic stability by preventing telomere dysfunction (PubMed:23776040).  Involved in the morphogenesis of basket cells in the somatosensory cortex during embryogenesis (PubMed:23912123).  Involved in the positive regulation of oligodendrocyte differentiation during postnatal growth (PubMed:24481677).  Involved in dendritic arborization, morphogenesis of spine density dendrite, and establishment of postsynaptic dendrite density in cortical pyramidal neurons (PubMed:25983680).  Involved in the regulation of neurogenesis.  Negatively regulates neurite outgrowth.  Involved in homologous recombination (HR) repair pathway.  Required for proper resolution of DNA double-strand breaks (DSBs) by HR.  Is required for recovery of stalled replication forks, and directly contributes to genomic stability.  Interacts with PARP1 and mediates MRE11-dependent DNA end resection during replication fork recovery (By similarity).
What are the official names of this protein?
Protein ZNF365, DISC1-binding zinc-finger protein, Su48.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: GCSPA_DESHY
Sequence: MNYVPNTVDQQEQILTRIGVGSLEELFADIPESVRRQAQLKIREGLSELELVKYMGRLAAENKTVEEYTSYLGAGAYEHFIPSYVDQLLLRSEFYTAYTPYQPEISQGTLQAIYEFQTLVCELTGMDGANASMYDGASALAEAALMSCDATRRKKVLVPQTIHPEYREVLRTYLLPRGVEILEIPYQEGAVDSEALEKALNTEVAAVLIQSPNFFGMIEKAEEIGQMAHAKGGLLVMAVNPVSLGLLKSPGELGADIVVGEGQPFGNPLNFGGPYLGFLACREKYVRRMPGRIVGATKDKNGKKGYVLTLQAREQHIRREKAASNICSNEALCALAFTIHLSGLGKRGLKEMARLNLQKAHYGAEEIGKLPGMSLAFQGPFFHEFVIKTEVSPRKINEALLSHKIIGGLELSRFYPELDQHLLFCVTETKTKEDIDRLVAGMGEIK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: Z_ALLVP
Sequence: MGLRYSKEVRDRHGDKDIEGRVPMTLNLPQGLYGRFNCKSCWFVNKGLIACGDHYLCLGCLTRMLSRTDFCEICSKPLPKKIIFEDSPSAPPYEP
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L.  Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z.  Also selectively represses protein production by associating with host eIF4E.
What are the official names of this protein?
RING finger protein Z, Protein Z, Zinc-binding protein.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae Z protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly perinuclear. During budding, associates at the inner side of the plasma membrane of infected cells.
Protein: EIF3L_CRYNB
Sequence: MADPSAFYEPEEDELLSQLAIPIQNYQPLSEGDEYRRLQQLEQHAYAQQTAMAQEQEMEQLAVLELIPEDVKRFLVMFHQAILENDLPTITSMYESGWNKLTQAHYLNNEWPEAELIAPLVGNDQVFLTLYRELYFRHVYARLQPTIDDRFQSYENICELFNYLLNSEGPVPLDLPIQWLWDMLDEFVYQFTSFSHWRSSPKAKTEEELEMLAESPNIWSSYSVLNVLYSLVQKSQINEQLKAERAGKSVEEVTEVAGEYGSKPLYKNLGYFSLICLLHVHVLLGDPTLALQTMENVDLGNAAFLTRITACHVTTYYHVGCAYMALGRWPDAIKTFVSVLIFFIRMKQYHTRSYQYGSIAKTCERMYALLAICTTLSPGPSDENIMTIVKEHYGDQLAILQRGGPEALEAFKDLYLQACPKYLNVNPPPYEDASALEAWLANPPADATQRHLELFLSDVQAVQGVNGMRNLLKLYTSIDAAKLAAFSVSGEEEGEEEVLQQLMVLKSASSTYGRGQAETTLLDGERKVTNNLDFTIDGTMVHVEETTSHRRYAGFFIRNAEHAQRALTSIKSAPLPVRKPASSSAPAPATTAAPISKSGESAAPAPAEAPAAPEKKAGTWVPKSRQARIAA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_SHIDS
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDAQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: GLBD_MOLAR
Sequence: MGATQSFQSVGDLTPAEKDLIRSTWDQLMTHRTGFVADVFIRIFHNDPTAQRKFPQMAGLSPAELRTSRQMHAHAIRVSALMTTYIDEMDTEVLPELLATLTRTHDKNHVGKKNYDLFGKVLMEAIKAELGVGFTKQVHDAWAKTFAIVQGVLITKHAS
What are the official names of this protein?
Globin D, coelomic.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS7_BURPS
Sequence: MPRRREVPKREVLPDPKYGNVDVAKFMNMLMLSGKKSVAERIVYGAFEQIQTKGGKDPLEVFTVALNNVKPVVEVKSRRVGGANYQVPVEVRPSRRMALAMRWLREAAKKRSEKSMALRLAGELSEAAEGRGGAMKKRDEVHRMAEANRAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.