PharMolix/UniProtQA huggingface dataset:
Protein: KPRS_LISWE
Sequence: MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSNYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEDSPIEKLIVTNSIALPEEKWIDKMEQLSVAPLLGEAIVRVHENASVSSLFE
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATS4_PONAB
Sequence: MSQTGSHPGRGLAGRWLWGAQPCLLLPIVPLSWLVWLLLLLLASLLPSARLASPLPREEEIVFPEKLNGSVLPGSGAPARLLCRLQAFGETLLLELEHDSGVQVEGLTVQYLGQAPELLGGAEPGTYLTGTINGEPESVASLHWDGGALLGVLQYRGAELHLQPLEGGTPNSAGGPGAHILRRKSPASGQGPMCNVKAPLGSPSPRPRRAKRFASLSRFVETLVVADDKMAAFHGAGLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPSAAQTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAYTAAHELGHVFNMLHDNSKPCISLNGPLSTSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACMGGRCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSVLTFREEQCAAYNHCTDLFKSFPGPMDWVPRYTGVAPQDQCKLTCQARALGYYYVLEPRVVDGTPCSPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGGDGSGCSKQSGSFRKFRYGYNNVVTIPTGATHILVRQQGNPGHRSIYLALKLPDGSYALNGEYTLMPSPTDVVLPGAISLRYSGATAASETLSGHGPLAQPLTLQVLVAGNPQDARLRYSFFVPRPTPSTPHPTPQDWLHRRAQILEILRRRPWVGRK
What is the function of this protein?
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover.  May play an important role in the destruction of aggrecan in arthritic diseases.  Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, ADAMTS-4, Aggrecanase-1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: GET1_EMENI
Sequence: MISLIWTIFILHIAIFLVNTIGAATIDNLLWLLYLKLPTSLYQTAQEQTKLKREVVQLKRDMNNTSSQDEFAKWAKLRRRHDKALSEYEALNQKLSSQKGSFDWFVKIARWLSTTGLKIFIQFRYSKTPVFELPGGWLPYPVEWVLAFPRAPQGSVSVQVWNSVCATAVTVIAEIITGLALQVKGSAQAVPATAKKA
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein get1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS11_SHESR
Sequence: MAKVPSRSPRKRVRKQVADGMAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGAAAQDYGLKNLEVFVKGPGPGRESAIRALNAVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DP71L_ASFM2
Sequence: MSRRNKRSRRRRKKPLNTIQPGPSKPSAQDEPIKSVSHHSSKIGTNPMLAFILGGNEDLSDDSDWDEDFSLENTLMPLNEVSLKGKHDSKHFNKGFDNNTALHEVNTKWEAFYSSVKIRQRDVKVYFATDDILIKVREADDIDRKGPWEQAAVDRLRFQRRIADTEKILSAVLLRKKLNPMEHE
What is the function of this protein?
Interacts with the host phosphatase PP1 catalytic subunit (PPP1CB) and recruits it to dephosphorylate EIF2S1/eIF2alpha and therefore restores the host translation that has been shut-down by the host.  Also inhibits the EIF2S1/eIF2alpha-ATF4-DDIT3/CHOP pathway.
What are the official names of this protein?
Protein DP71L, MyD116 homolog.
What is the protein family that this protein belongs to?
Belongs to the asfivirus DP71L family.
Protein: MNMG_LYSSC
Sequence: MPTKYEAGTFDVIVIGAGHAGSEAAHAAAKMGAKTLMLTINLDMIAFMPCNPSIGGPAKGIVVREIDALGGVMGKVIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRILEETENLTIHQGMVEELIIEDGEVTGVITQIGAIYRAKTVVVTTGTFLRGEIIIGDIKYSSGPNNQQPSIRLADNLKELGFDLVRFKTGTPPRVNNRTIDYDKTEIQPGDEVPRAFSFETTEFIMDQLPCWLTYTSPETHEIIEANLHLSPMYSGMIKGTGPRYCPSIEDKVVRFNDKPRHQIFLEPEGRNTREVYVQGLSTSLPEHVQTRLLKSIPGLENAEMMRAGYAIEYDSIVPTQLWPTLETKRIKGLYTAGQINGTSGYEEAAAQGLMAGMNAAANVLGKEELILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLLELAYKIGMVPQERYDKFNAKKALIENEIARLREIIIKPNEATQAVIRSAGGSELKDGIRGADLLKRPEMHYEMISSLIPADIEFTEEVKEQIEIQLKYEGYIEKALLQVEKLHKMENKKIPENIDYDAISGLATEARQKLKQVTPLSIAQASRISGVNPADISILLVYIEQGKIAKISG
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_PSEA7
Sequence: MKRTFQPSTLKRARVHGFRARMATKNGRQVLSRRRAKGRKRLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PRM10_ASHGO
Sequence: MGKNKKQAAEGEEARRGSESSGSSAEPSGAVAELPSFKKTAGGARSGLIEQDAVDTIREQTAVKFADEDEVVEQDEAAQKTEAVASESSSLADKEECDESKLDHFRKFFRRTSSRSSDEGEGGGMMERFINMTGGGMVPVVTEAPEEDEEAGPDPTAEAEAAAREIMKAHHLSSGQSVDMMSMSSSGESGFFMPVAEHYDDEYNPEQEEEQRDDMSEATYVPPPQHVRGGVLGSLLRLYQNQPGGQAPQRPGLRKSAQTLSSETLPTGESYEMPKFKAKRPRGSKIPNPIKLKRKSAMSEARITVHIADLLQRHRFILRLCKAFMMYGAPTHRLEEYMVMTSRVLEIDSQFLYLPGCMVVSFGDTITRTSEVQLVRCSQGLNLWKLHQVHSIYKQVVHDIISVEDASRTIETIMAEKNLYPAWMCVLLYGFCASMVTPFAFGGDWINLVVSFGIGCCVGLLQFIVAQRSHVYSNVFEITASIVVSFCARALGSIPNSNICFGSTVQGSLALILPGYIILCGSLELQSRSLVAGSVRMFYAIIYSLFLGFGITLGAALFGWIYRDATNETVCEKELSPWFRFIFVPGFALGLSLINQARWSQIPVMVCIACSGYVVTYWSGQHFTASTEFTASIGAFVIGIMGNLYSRIWKGLAMTAMLPGIFVQVPSGIASKSTLLSSVQSANNMVSNGTNAAVNSVDGRTSISFGITMIQVCIGISVGLFASTLVVYPFGKKRTGLFTL
What are the official names of this protein?
Pheromone-regulated membrane protein 10.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SAHH_PSEMY
Sequence: MSAVLTPAGFTDYKVADISLADWGRKELIIAESEMPALMGLRRKYAASQPLKGAKILGCIHMTIQTGVLIETLTALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCIEQTILKDGKPWDANMVLDDGGDLTEILHKKYPQMLERIHGITEETTTGVHRLLDMLKAGTLKVPAINVNDAVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSAQSLRQEGMIVKVSEIDPICAMQACMDGFELVSPYKNGINDGTESSVDAALLGKIDLIVTTTGNVNVCDAGMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGAGQFDPTNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIFLFEQKFADLPAEKKAERLTVEVLPKKLDEEVALEMVKGFGGVVTQLTKQQAEYIGVTVEGPFKPDTYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM1L_MACFA
Sequence: MENMAEEELLPLEKEEVEVAQVQVQVPSLASAPEEAKSKRHISIQRQLADLEKLAFVTEGNFDSTSSLNSDNLDAGNRQACPLCPKEKFRACNSHKLRRHLQNLHWKVSVEFEGYRMCICHLPCRPVKPNIIGEQISSKMGAHYHCIICSATITRRTDMLGHVRRHMNKGETKSSYIAASTAKPPKEILKEADTDVQVCPNYSIPQKTDSYFNPKMKLNRQLIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQENCYLNKLKVVVDSKEKEKSDDILEEGEKNIGNIKVTKMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLFESLHHGLDDIQTLIKTLIFESECTPQSQFSIHTPSNLNKQEENGVFIKTTDDTITDNYIAQGKRKSNEMITNLGKKQKTDVSTEHPPFYYNIHRHSIKGMNMPKLKKFLCYLSQAGFRVSRTHFDPMGVRTDAPLMQFKSILLKYSTPTYTGGQSESLVQSASEDTVTERVEMSVNDKAEASGCRRW
What is the function of this protein?
May play a role in motor coordination and exploratory behavior.
What are the official names of this protein?
TRMT1-like protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: RSMB_ECO81
Sequence: MKKQRNLRSMAAQAIEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLEWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAVAIKRPQLKGLINGVLRQFQRQQDELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIVEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVQLETPAPVHALPGFEEGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVLAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWSHLKSGGTLVYATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP387_ARATH
Sequence: MRYQQWRLMLLRSYHRSHLPYLSPCSQVTSISSRSFSSFIHPGIGALQQSEQLCPLRSPMTSSGNLVKSVGRSFSSEPAVEEKSSAEATVIDIFSRLSGEDEIRKELESSGVVISQDLALKVLRKLESNPDVAKSFFQWIKEASPEELSSKNYNMMLRILGGNGLVDEFWGLVDVMKKKGHGLSANVRDKVGDKFQKDGLESDLLRLRKLFTSDCLDNSAENVCDRVCKIVMKEEWGDDVEKRVRDLNVEFKSDLVKMIVERLDVEPRKALLFFRWIDESDLFKHDEKTYNAMARVLGKEKFLDRFQNIVVEMRSAGYEVEIETYVRVSTRFCQTKLIKEAVDLFEIAMAGSSSSNNPTPHCFCLLLKKIVTAKILDMDLFSRAVKVYTKNGNALTDSLLKSVLKSLRSVDRVEQSNELLKEMKRGGYVPSGDMQSMIASSLSRKGKKDEADEFVDFMESSGNNLDDKAMASLVEGYCDSGNLDEALVCFEKMVGNTGVSYADYSFEKLVLAYCNKNQVRDAYKLLSAQVTKNQLKPRHSTYKSLVTNLLTKKIARDGGFEEALSLLPIMKDHGFPPFIDPFMSYFSSTGKSTEALGFLKAMTSNNFPYISVVLRVFETMMKSARHSEAQDLLSLCPNYIRNNPDVLELFNTMKPNESAVEKPLAASA
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g15980, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: 3F_DICDI
Sequence: MKLLSKLILTLALATYASASESFRYINWDNPPHDVTFYEGDVLQFTTNEGRNSTITLISDTENGDKSFDGVLNEDQRSFVQKALPPGRYTFKDLNSGSKSIIRVKESKELAKEVRPIDRLKDNADAANTENAQKSPNTQSTQKGSPKSDAKEASPKTDAKEASPKSDAKEASPKTDTKQGSSPKTDTKSSTQKPSSSSDSSKAKAEANTAANNEEAEHVEKGASNTLKASLSIISAACVLSLGYLL
What are the official names of this protein?
Protein 3F, Prespore-specific gene protein.
Protein: RL23_YERPA
Sequence: MIREERLLKVLRSPHVSEKASAAMEKNNTIVLKVAKDATKAEIKAAVQKLFEVEVEDVNTLLVKGKSKRHGQRVGRRSDWKKAYVTLKEGQNLDFIGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: YM116_YEAST
Sequence: MAKQQITERRREDLLQGIERYQDLTSWPNTLHKCNIRHLCMQPIFWAPLRKTTRILTSSIAVLSLKYNAYPSDYLDKAQGSLRRPAKVFLPFFLRFLCIN
What are the official names of this protein?
Putative uncharacterized protein YML116W-A.
Protein: MAK5_KLULA
Sequence: MVYGVSKMANKNRKNLKPVKSDRKDRISKNHSKKKVNKNSLKKVATTDITVNANELNWKSVDIPDTLDDFGGFYGLEEIDGVDVKVVDGKVQFITKDNKNVKKEPEQVEEKDNIVFQEDDEDVNMDELIEFKNFDDIKEGELSAASDDEESEFHVSTEEEGEEGEEAEDQEEERSEKENVKGEAGTVVTEDQTNDDLLQSNVFSSNVDIDDQEPPVLPEWSENMDLSFTVLKGLSGLGFTRPTEIQLKSIPLALKGHNIMGKASTGSGKTLAYGIPIIEQLIKDTSNDRSIGLIFTPTRELAHQVTDHLQKVWTKMNKLNKYTILSLTGGLSIQKQERILKYDGSGRIIVATPGRFLELLERNPDLIPRFAKIDTLVLDEADRLLQDGHFDEFEKILKLLGKARKIKTSIDGKPTGSGWQTMIFSATFSLDLFTKLDKTSWKILKTAGGENNEMEQVLNHLMKKIQFKSKPVIIDTNPEHKVTSQVKESLIECLPMERDLYVYYFIMMYPGTTLVFCNAIDSVKKLNAFLNNLKISSFQIHSSMAQKNRLRNLEKFKEQSEKNSKVGKPTILIASDVAARGLDISGIKHVLHYHLPRSADVYIHRSGRTARGDNEGVSVMICSPQESMGPLRKLRKVLSTKKSSNPRKTKWQNDVPMLPLEPDIVSQLRERSKIASELADDEIATKSLHKDDNWLKKAAEELDIELDSEEEEKDQFLARNKTKKLNKQLEKNENKALKYQLNELLKMPLRKDLRKSYLTGGLTNLADTLVKHKGHNSIIGHDKVDALQTLKGKKHK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase MAK5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SDH7A_ARATH
Sequence: MAFLLNTSISSHLRSSSQKTDGALAQSRRGFHVELGAREKALLAEDASLRRFKSHKKGVHRLKRIGDVLTVVVVAGCCYEIYARVMRKEAQAA
What are the official names of this protein?
Succinate dehydrogenase subunit 7A, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: AGO3_ARATH
Sequence: MDRGGYRGGRGDGRGRGGGGDRGRGYSGRGDGRGRGGDGDRGYSGRGDGHGRGGGGDRGRGYSGRGDGRGRGGGGDRGRGYSGRGDGHGRGGGGDRGRGYSGRGRGFVQDRDGGWVNPGQSSGGHVRGRGTQLQQPPPQEVPPSSSQAQVSQGVAPGDVGQGGVGDVGRDGVGDVGRDGVGDVGQGGVGDVGQVGVGDVGQGGVGDVGQGGVGDVGRDGVGDVGRDGVGDVGRGGVGDRGQSQSGLSSGHFGRGTQLQQPQPQAVSQSSSQGQVSQSFATGGVGLGAWARKPQLFSDSTVLPSSSSSNVVASHTASGSQVMTPKPSSSDKKEPVKRPDKGGNIKVKGVINLSVNHFRVSFSTESVIRHYDVDIKGENSSKKISRFELAMVKEKLFKDNNDFPNAMTAYDGQKNIFSAVELPTGSFKVDFSETEEIMRGRSYTFIIKQVKELKLLDLQAYIDGRSTFIPRDVLQGMDVVMKEHPSKRMITVGKRFFSTRLEIDFGYGVGAAKGFHHTLKPTVQGLSLCLNSSLLAFRKAISVIEYLKLYFGWRNIRQFKNCRPDDVVQELIGLKVTVDHRKTKQKFIIMGLSKDDTKDIKFDFIDHAGNQPPRKISIVEYFKEKYGRDIDHKDIPCLNLGKKGRENFVPMEFCNLVEGQIFPKEKLYRDSAAWLKELSLVTPQQRLENINKMIKSSDGPRGGDIIGNFGLRVDPNMTTVEGRVLEAPTLKLTDRRGNPIHEKLMSESNQWNLTTKGVTKGSIIKHWAVLDFTASESLKKKMPGYFVNKLIERCKGLGMQMEAPIVCKTSSMETLYDGNALEELLRSVIDEASHNHGGACPTLVLCAMTGKHDGYKTLKWIAETKLGLVTQCFLTISAIKGETVSDQYLANLALKINAKVGGTNVELVDNIFSFFKKEDKVMFIGADVNHPAAHDNMSPSIVAVVGTLNWPEANRYAARVKAQSHRKEEIQGFGETCWELIEAHSQAPEKRPNKIVIFRDGVSDGQFDMVLNVELQNVKDVFAKVGYNPQITVIVAQKRHQTRFFPATTSKDGRAKGNVPSGTVVDTTIIHPFEYDFYLCSQHGAIGTSKPTHYYVLSDEIGFNSNQIQKLIFDLCFTFTRCTKPVALVPPVSYADKAASRGRVYYEASLMKKNSKQSRGASSSSASVASSSSSVTMEDKEIFKVHAGIENFMFFV
What is the function of this protein?
Involved in RNA-mediated post-transcriptional gene silencing (PTGS).  Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA).  RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression (By similarity).
What are the official names of this protein?
Protein argonaute 3.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
Protein: PDXJ_CUPNH
Sequence: MIFHANPGVIDLGVNIDHVATLRNARGTVYPDPIRAALLAEQAGADLITLHLREDRRHIRDADVRALRPQLATRMNLECALTQEMLDIACEIRPQDVCLVPERREEVTTEGGLDVAGRFEQVKAACAQLAGAGIRVSLFIDADADQIAAAAACGAPVIELHTGRYADAHTPDEQALEFRRIADGVDAGQKHGLVVNAGHGLHYTNVQPIAALPGIKELNIGHAIVAHAVFAGWENAVREMKAIMVAARLGTRYPAAGAPA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_CAMJE
Sequence: MIDVMQIQEILPHRYPFLLVDKITELKVKEVVLGYKNISISDHVFMGHFPGHPIYPGVLILEGMAQTGGVLAFESMEDKVDPKSKVVYFTGIDGAKFRNPVRPGDRLDYEMSVVKNRGNMWIFKGQAFVDGNLVAEAELKAMIVDK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECH1_DICDI
Sequence: MEGSLFFTNATPSTSILKITDYKYLRLEKNDSTFVAELVLCRPKQYNSMDDDFYNEFISIYDEIQNDSKIRCVILRGEGKGLTAGLNLGKIAPLITGDSEVSQSQNNLDLFKMIRRWQASLDKINKCSKPTIALIHGACIGGGVDMITACDIRLCSSDAKFSIRETKLSIIADLGTLQRISKIVGSGFARELALTGKDIDAKTAERFNLVNHVYPDHDTLLSEGRKLALSIAQNSPLVVQATKLTLNHADDHTIDEGLYRVALQNAAFLKSDDLNESATSFFEKRQPIFKCNL
What is the function of this protein?
Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA.
What are the official names of this protein?
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MURB_SYNC1
Sequence: MHVLAARLGEILHSPVQLGEPLSRHTSWRIGGPAEIFLSPCDTKELVASLELLAQVGMPWIALGAGTNVLVRDGGFRGAVIHTGGLQDMAFDADGRARVGGGVPVMRLIRHCVERGLAGLEDLAGLPATIGGAVVMNAGAGKQDLAGVLDGAFLAGPSGVEYWPADRLELGYRTSAVPPGRIVTAASLRFRKASPEVLETYVRQRVQQRRKAQGVGKPNAGSVFKNPPGQQAWRLIDSCELRGFAVGGAQVSEKHANFIVNRGGARAEDVLRLIAEIQKKVEKRTGIVLEPEVKVVGQA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3134_GLOVI
Sequence: MVGRPVEPGALLQGQTVTVPITALAAGGDGIARLTDGRVLFVAGAVPGDTVEARLVHLKKDHGFGKILQIVQASPHRIEAPCPVAERCGSCQWQWIDYPFQLEAKQRQVREALEHLGGFAEPPVEPVIAQPRPFGYRNKSTFPIGRDARGEPVIGYYQKDSHRIVPLDACPVQDSRLDPLLAAARELIRTQGWSIYDEKHHRGALRHLGLRIGERTGQRLLTFVVNGQTLSGIKPAAQALMDRFADLVGVCLNTHTERGNTIFGPQTRCLAGQDFIEEVLDGFRFRIEPTTFFQICTSQAEILARLVARGADATAEQTVVDAYCGIGTLSLPLARAARAVVGIESHVRSVEQARQNARINGIENCRFLAGTVEALLPDLRADIVVVDPPRKGCDPEVLEAILHAVPMRVVYVSCNPATLARDLKRLVAGGYCLVGVQPVDLFAQTHHVECVATLERS
What are the official names of this protein?
Uncharacterized RNA methyltransferase gll3134.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: ATG15_LODEL
Sequence: MLHITEKEQTRGLRQLEKRGKRLLPPLIKFIWFCLISAACVAATTFYWLRLSPVHNIHKHSLNSSFEDKGEDGTLQLKHIFHHGVGEKDYKIHKRLDVTQEYLIKHSAYFQNMVNEQQQEVQEIQEIHKRHEKQEIQVKYGPDQEYNQTNTALNSVGTEYKSRLSTNEYDWPDVHRGKNPFDIQLPFKNKQSIARRIKHRNEPFFIESYLDYARSVNGDALILNRINLEWIDDDINIPNITDKDTIVTLATISSNAYVRFPQNDDDKKKSDWTDVGGGWIPDEENNDVNFGWEDVGLRGHIFVSKDNKTVVIGIKGTSGAGLPGGGSDETTKNDKTNDNLLFSCCCARVGYMWTTVCDCYEKAYTCNQDCLEKELRRKDRYYEAALDIYKNVTAIYPPETTDIWVTGHSLGGALASLLGRTYGLPTVAYEAPGEMLALKRLHLPQAPGLPRHLEHIWHIGNTADPIYMGVCNGASSSCSLGGYAMETACHTGYQCVYDVVTDYGWRVNLLNHRIHTVIDDIILVYNETAPCVYQAPCRDCFNWRFVSHDDKE
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase ATG15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: KADA_METMP
Sequence: MKNKVVVVTGVPGVGGTTVTQKAMDILSEEGLNYKMVNFGSAMFDVANEEGLASDRDQMRRLDPETQKRIQKMAGRKIAEMAKESPVAVDTHSTVKTPKGYLPGLPAWVLTELNPDIVIVVETDGDEILMRRLSDESRKRDLETTASIEEHQFMNRAAAMSYGVLTGATVKIVKNKNGLVDNAVEELMSVLR
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_EHRCR
Sequence: MKKIVLAYSGGLDTSVILKWLQENYNCEVVVFTADLGQNDDMSAIRQKAAASNVKEIFIEDLKEEFVKDFVFPMFRANTVYEGYYLLGTSIARPLIAKRQIEIAHLTGADAVAHGATGKGNDQIRFEFGYYSCDPNIKVIAPWRQWELTSRNSLIEYAKKHGIDVPLDKASEPPYSIDANLLHTSYEGKSLEDPYIEPDYTMLSKSVIPELASDTPEYIEISFKNGDPHAINNVPLSPANLLQQLNIIGGRHGIGIIDIVENRYIGIKSRGVYETPGGTILLHAHRAIESITLDREAAHLKDEIMPRYAKLIYNGYWWTTERKMLQALIDKSQDKVNGVVRLKLYKGSVMVVGRTSENSLYSHNLASFDSSGNYNHTDAEGFIKINSLRLRNS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_CORDI
Sequence: MSTQTRVRHFLADDDLTPAQQREVLELASELKQHPYSRKTYDGPQSVAVLFDKTSTRTRFSFDAGISQLGGHAIVVDSGKSQMGKGETFQDTGAVLSRFVSTIVWRTGSHQNLLDMAETATVPIVNALSDDLHPCQILADLQTCIEHLCPQEGVPGLKGLKAVYLGDGDNNMANSYMIGFATAGLDITIIAPKKFQPKQEFVDRAEKRASETGAIVSVTADISAVSDADVVITDTWVSMGMENDGIDRRTPFLPYQVNDEVMALAKKSAIFLHCLPAYRGSEVAASVIDGPQSVVFDEAENRLHAQKALLVWLMENQPR
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_MYCVP
Sequence: MTETAPAIEAILAEYGELEQRLADPELHADPAAAKKVGRRFAQISPIVSTYHKLEAARGDLEAARELAADDASFAAEVDELTTKVADLDDRLTDLLAPRDPHDADDIVLEVKSGEGGEESALFAADLARMYIRYAERHGWTVTMLGETTSDLGGYKDATLSIAGKGDSADGVWSRLKFEGGVHRVQRVPVTESQGRVHTSAAGVLVYPEPDEVEQVQIDESDLRIDVYRSSGKGGQGVNTTDSAVRITHLPTGIVVTCQNERSQLQNKARAMQVLAARLQALAEEQASADASADRASQIRTVDRSERIRTYNYPENRIADHRINYKSHNLDQVLDGDLDPLFDALAAADKQARLQNT
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRS54_RAT
Sequence: MAELRGILLLLLYMSHSSSAICGIQKANIVDQLHENLVSSTEFPWVVSIQDKQYTHLAFGCILSEFWILSTASALQNRKEVIAVVGIANMDPRNADHKEYSINAIIPHENFNNNSMRNNIALLRTDSAIHFDDLVQPICFLGKSLHKPTALKNCWVAGWNPTSATGNHMTMSILRRISVNDIEVCPLHRQQKTECASHTNKDSNVCLGEPGNPMMCQVKKLDLWILRGLLAYGSDLCPGLLLYTSVDDYSNWIIAKTRKAGPPLSSIHPWEKLVLELPFHQSNIALTKNSYSVHSYAWPQSYSQGLRMSTMYDKQKDVWQNLRVNGQQEAGRPSNVAIQPMYYDYYGGEAGEGRAVAGQNRLHWSQERILMSFVLVFLGSGV
What are the official names of this protein?
Inactive serine protease 54, Plasma kallikrein-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasma kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.