PharMolix/UniProtQA huggingface dataset:
Protein: PTA_NITEU
Sequence: MHTFFVTSTGFGVGLTSTSLGLVRALEYGGLKAGFYKPVAQQHPGNSKLEYSTELISRTLGLAPPAPLPLATVEHLLGEGQIDDLMEDIVRRFKQASEGYDVMVVEGMVPTRHVSYASRVNTRLASSLDADIILVSSAEDDALQAITDRIEIQAQFFGGAQNPRLLGVILNKIRTDHSDDLFEQLKNHSTLFHQSSFQILGCIPWEDSLNAPRMADVVTQLQAQIVNAGDSEKRRVQDIVLFASAAPNSVTLLRPGVLVVTPGDRDDIVMAASLAVLNGVPLAGLLLCSDFPPDPRVLELCKGALTKGLPVCTVTTNSYDTAANLHRMNREIPLDDHERAERITNFVANHIRQELLVKRCGEPQEQRLSPPAFRYRLVKRAQEADCRIVLPEGYEPRTIQAATICQERGIARCVLLAKPDAVKAVASARGITLPEGLEMIDPEKVRRNYVAAMVELRKHKGLNEPMALAQLEDNVVLGTMMLATGEVDGLVSGAINTTANTIRPALQLIKTAPGFKLVSSVFFMLLPEQVVVYGDCAVNPNPTAEELADIALQSAASAQALGIEPRVAMLSYSTGDSGSGQEVEKVREATRLARLARPDLLIDGPLQYDAAAIASVGRQKAPGSPVAGRATVFIFPDLNTGNTTYKAVQRSANVVSVGPMLQGLRKPVNDLSRGASVEDIVYTIALTAVQAASQR
What is the function of this protein?
Involved in acetate metabolism.
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_ECODH
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATOSB_RAT
Sequence: MRHVQAELSPSSEPEAGPSQPPVTQGTLQGGLLMGYSPAGGATSPGVYQVSIFSPSAGVSEPPRALKRPAPSTEGPRELKRGPGLGAREGLPPEEPSTVGLVSPEGLGLGLGVASQHFSHHGLRVVEQGGSATSSWTSGTQSTPWPSSNASCNTLHTRDWAFPDQGGQGCLGESPGPAPSGQLHTLDTDLHNLAQIGGKSPVARVGNGSNPWPRESHGTANGHSPEHTPPGPGPPGPCPTKRRLLPAGEALDVSSEDEGPAPRRRRGTLGCPLAANSSDAKATPFWSHLLPGPKEPVLDPTDRSPMGRRLKGARRLKLSSLRTLRKGPGLLSPPSASPFPTPAVSRTLLGNFEESLLRGRFAPSGHIEGFTAEIGASGSYCPQHVTLPVTVTFFDVSEQNAPAPFLGVVDLNPLGRKGYSVPKVGTIQVTLFNPNQTVVKMFLVTFDFSDMPAAHMTFLRHRLFLVPVGEEGNVSPTHRLLCYLLHLRFRSSRSGRLSLHGDIRLLFSRRSLELDTGLPYELQAVTEAPHNPRYSPLP
What is the function of this protein?
Transcription regulator that may syncronize transcriptional and translational programs.
What are the official names of this protein?
Atos homolog protein B.
What is the protein family that this protein belongs to?
Belongs to the ATOS family.
Protein: PSBD_STIHE
Sequence: MTITIGQYVEKRGLFDNVDDWLRRERFVFVGWSGLLLFPCAYMALGGWLTGTTFVTSWYTHGLATSYLEGCNFLTAAVSTPANSMAHSLLFLWGPEAQGDLTRWFQLGGLWPFVALHGAFSLIGFMLRQFEIAQSLKLRPYNAIAFSAPIAVFVSVFLIYPLGQAGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHEKLTFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RP54_RHIME
Sequence: MALSASLHLRQSQSLVMTPQLMQSIQLLQMNHLELSHFIAQEVEKNPLLEVQPADEPTISDREDAGPHPAETGGETDEAAGQSDLYDSAMSRSGERLSEGLDADFANVFPDDTAPQRADAPELLGQWKSMPGAGDAEGYDLDDFVGGRKTLRETLAEQLPFALSAVSDRLIARYFIDQLDDAGYLHADLAETAETLGAAGEDVARVLHVLQQFDPPGVFARTLGECLAIQLRARNRLDPAMEALVANLELLARRDFASLKKICGVDEEDLIDMLAEIRKLDPKPGTSFETGVFEAIIPDVVVRAAPDGGWLVELNPDALPRVLVNHDYFTEISRSSRKNSGEQAFLNECLQNANWLTRSLDQRARTIMKVASEIVRQQDAFLIHGVGHLRPLNLRIVADAIKMHESTVSRVTSNKYMLTPRGLFELKYFFTVSIGSAENGDAHSAESVRHRIRTMINQESADAVLSDDDIVDVLKQAGVDIARRTVAKYREAMSIPSSVQRRREKRALAKAAGF
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is responsible for the expression of the nitrogen fixation genes (nif operon), glnA and dctA for dicarboxylate transport.  The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator proteins NifA, NtrC, or DctD for the expression of the regulated proteins.
What are the official names of this protein?
RNA polymerase sigma-54 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-54 factor family.
Protein: CADM3_MOUSE
Sequence: MGAPSALPLLLLLACSWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVSSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKETATLNCQSSGSKPAAQLTWRKGDQELHGDQTRIQEDPNGKTFTVSSSVSFQVTREDDGANIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPEPAHPREGQKLLLHCEGRGNPVPQQYVWVKEGSEPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYTAYFTLNVNDPSPVPSSSSTYHAIIGGIVAFIVFLLLILLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI
What is the function of this protein?
Involved in the cell-cell adhesion.  Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3.  Interaction with EPB41L1 may regulate structure or function of cell-cell junctions.
What are the official names of this protein?
Cell adhesion molecule 3, Immunoglobulin superfamily member 4B, IgSF4B, Nectin-like protein 1, NECL-1, Synaptic cell adhesion molecule 3, TSLC1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction.
Protein: ATPD_BACC0
Sequence: MSNGIVAKRYAVALFKIAKEKHVLEMFEEELRLVQNVYEKNGELHSFLTQPNISKEQKKTFLANVFGSVSESILNTLYILIDNKRIDILSDIANEYVVLANEERNVADATVYSTRLLSEEEKLNIAEAFAKRTGKDAIRVKNVVDEDLLGGIKVRIGNRIYDGSLQGKLARIQRELMKNR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RBM7_HUMAN
Sequence: MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHEVSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSRYERTMDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRDDFFYEDRNHDDWSHDYDNRRDSSRDGKWRSSRH
What is the function of this protein?
RNA-binding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation (PubMed:25189701, PubMed:25578728, PubMed:25525152, PubMed:25852104, PubMed:27871484).  NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs (PubMed:25189701, PubMed:27871484, PubMed:25852104).  Binds preferentially polyuridine sequences and associates with newly synthesized RNAs, including pre-mRNAs and short-lived exosome substrates such as promoter upstream transcripts (PROMPTs), enhancer RNAs (eRNAs), and 3'-extended products from small nuclear RNAs (snRNAs) (PubMed:25189701, PubMed:25578728, PubMed:25525152, PubMed:25852104).  Participates in several biological processes including DNA damage response (DDR) and stress response (PubMed:25525152, PubMed:30824372).  During stress response, activation of the p38MAPK-MK2 pathway decreases RBM7-RNA-binding and subsequently the RNA exosome degradation activities, thereby modulating the turnover of non-coding transcriptome (PubMed:25525152).  Participates in DNA damage response (DDR), through its interaction with MEPCE and LARP7, the core subunits of 7SK snRNP complex, that release the positive transcription elongation factor b (P-TEFb) complex from the 7SK snRNP.  In turn, activation of P-TEFb complex induces the transcription of P-TEFb-dependent DDR genes to promote cell viability (PubMed:30824372).
What are the official names of this protein?
RNA-binding protein 7, RNA-binding motif protein 7.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus. Note=Excluded from the nucleolus.
Protein: RPOA_METS4
Sequence: MVIQKNWQELIKPNKLEVVPGHDPKRVATVVAEPLERGFGTTLGNALRRVLLSSLQGAAVTSVHIDGVLHEFSSIPGVREDVTDIVLNIKTIAIRSNSDAPKRMTLRKTGPGLVTAGDISTIGDIQILNPDLVLCTLDEGAEIRMEFTVATGKGYVPADRNRPEDAPIGLIPVDALFSPVTKVSYRIENTREGQDLDKDKLTMTVETNGAVSPEDALAYAARIIQDQLQIFVNFEEPRKEEAAPLAPQLPFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLAAMGLHLGMDVPGWPPENIEDLAKRFEEHY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: CARB_BACCL
Sequence: MPKRRDIETILVIGSGPIVIGQAAEFDYAGTQACLALKEEGYKVILVNSNPATIMTDTEIADKVYMEPLTLDFVARIIRKERPDAILPTLGGQTGLNLAVELAKAGVLEECGVEILGTKLEAIEKAEDREQFRALMNELGEPVPESAIIHSLEEAYAFVEQIGYPVIVRPAFTLGGTGGGICTNEEELVEIVSTGLKLSPVHQCLLERSIAGYKEIEYEVMRDANDNAIVVCNMENIDPVGIHTGDSIVVAPSQTLSDREYQLLRNASLKIIRALGIEGGCNVQLALDPDSFRYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMINPVTGKTYACFEPALDYVVTKIPRFPFDKFESANRRLGTQMKATGEVMAIGRTFEESLLKAVRSLEIGVHHLELNEAKTAADDVMEKRIRKAGDERLFYIAEALRRGVTVETLHEWSQIDRFFLHKIQNIIEMETVLKNHPGDLDVLKKAKGLGFSDAAIAALWNKTERDIYAVRRQRGIMPVYKMVDTCAAEFTSETPYYYSTYEEENESIVTEKPSVIVLGSGPIRIGQGIEFDYATVHCVWAIKQAGYEAIIINNNPETVSTDFSTSDKLYFEPLTAEDVMHVIDLEQPIGVIVQFGGQTAINLAAELEARGVRLLGTTLEDLDRAEDRDKFEQALSELGIPKPAGKTAVSVEEAVAIAEEIGYPVLVRPSYVLGGRAMEIVYNRGELLHYMEHAVRVNPQHPVLVDRYITGKEVEVDAIADGETVVIPGIMEHIERAGVHSGDSIAVYPPQTLSAEVIDKIADYTIRLARGLHIVGLLNIQFVVSGSDVYVLEVNPRSSRTVPFLSKITGVPMANLATKAILGTKLAEMGYETGVCPVRPGVYVKVPVFSFAKLRNVDISLGPEMKSTGEVIGKDVTFEKALYKGLVASGIHIQPHGAVLLTVADKDKEEAVELARRFADIGYQLLATNGTAETLKAAGIPVTVVNKIHSASPNILDVIRQGKAQVVINTLTKGKQPESDGFRIRREAVENGIPCLTSLDTARAMLQVLESMTFSTTAMTEGLVRS
What are the official names of this protein?
Carbamoyl-phosphate synthase pyrimidine-specific large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: AUHM_HUMAN
Sequence: MAAAVAAAPGALGSLHAGGARLVAACSAWLCPGLRLPGSLAGRRAGPAIWAQGWVPAAGGPAPKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE
What is the function of this protein?
Catalyzes the fifth step in the leucine degradation pathway, the reversible hydration of 3-methylglutaconyl-CoA (3-MG-CoA) to 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) (PubMed:12434311, PubMed:16640564, PubMed:11738050, PubMed:12655555).  Can catalyze the reverse reaction but at a much lower rate in vitro (PubMed:16640564).  HMG-CoA is then quickly degraded by another enzyme (such as HMG-CoA lyase) to give acetyl-CoA and acetoacetate (PubMed:16640564).  Uses other substrates such as (2E)-glutaconyl-CoA efficiently in vitro, and to a lesser extent 3-methylcrotonyl-CoA (3-methyl-(2E)-butenoyl-CoA), crotonyl-CoA ((2E)-butenoyl-CoA) and 3-hydroxybutanoyl-CoA (the missing carboxylate reduces affinity to the active site) (PubMed:16640564).  Originally it was identified as an RNA-binding protein as it binds to AU-rich elements (AREs) in vitro (PubMed:7892223).  AREs direct rapid RNA degradation and mRNA deadenylation (PubMed:7892223).  Might have itaconyl-CoA hydratase activity, converting itaconyl-CoA into citramalyl-CoA in the C5-dicarboxylate catabolism pathway (PubMed:29056341).  The C5-dicarboxylate catabolism pathway is required to detoxify itaconate, an antimicrobial metabolite and immunomodulator produced by macrophages during certain infections, that can act as a vitamin B12-poisoning metabolite (PubMed:29056341).
What are the official names of this protein?
Methylglutaconyl-CoA hydratase, mitochondrial, 3-MG-CoA hydratase, AU-specific RNA-binding enoyl-CoA hydratase, AU-binding protein/enoyl-CoA hydratase, Itaconyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ISDE_STAAS
Sequence: MRIIKYLTILVISVVILTSCQSSSSQESTKSGEFRIVPTTVALTMTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDEMQPFYKQLNMKGYFYDFDSLKGMQKSITQLGDQFNRKAQAKELNDHLNSVKQKIENKAAKQKKHPKVLILMGVPGSYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLNINPDIILRLPHGMPEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDADKAMTQLYDLFYKDKK
What is the function of this protein?
Involved in heme (porphyrin) scavenging.  Binds Fe(2+) and Fe(3+) heme but the largest fraction is Fe(2+) heme.  Functions as a high-affinity heme binding protein and probably has a role in relaying heme-iron from cell wall-anchored isd proteins receptors to the probable permease IsdF (By similarity).
What are the official names of this protein?
High-affinity heme uptake system protein IsdE, Iron-regulated surface determinant protein E, Staphylococcal iron-regulated protein F.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 8 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GUAA_SALRD
Sequence: MHDKIVVLDFGSQYTQLIARRVRETGVYSEIRPCTVEADAIDALNPSGVILSGGPCSVYDEAGPALDPALLELERPDGTPVPLLGICYGLQAMAHQFGGEVARADRREFGRAQLQVPPDGQEKSLLFEGVPSGSTVWMSHSDHLTDLPDGYEVIARTDNAPVAAVRDTDGPYYGVQFHPEVVHTDYGRQILENFAHAICGCSGDWTPASFVEEQTETIRDRVGDRHVILGLSGGVDSSVAAALLQRALGDQLHCIFVNNGLLRKGEWNQVQDTFRGHFEMDLRTTDATDRFLERLDGVTDPEEKRTIVGNTFIEVFEEQTEAIAADLGHRPTYLAQGTLYPDLIESVSFKGPSVTIKTHHNVGGLPEELDFDLIEPFRELFKDEVREIGRLLDVPDPIVGRHPFPGPGLAIRILGQITRERLALLREADAIFIEELRANDLYDEVWQAFAVLLPVQAVGVMGDERTYENVCALRAVTSVDGMTADWAHLPHDFLGHVSNRIVNEVPGINRIVYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: IF2P_METAR
Sequence: MATATEIRKDLRTPIVCVMGHVDHGKTSLLDRIRGTAVVDKEAGAITQHIGATEVPLQTIQTLCKGMIGGNIVVPGLLFIDTPGHHAFTNLRSRGGALADLAVLVVDINEGFQPQTVEAIKILKQFKTPFVIAANKIDRIHGWTAKNNSPFLQTFNSQPDHVKGIIETKTYELVGRMSDLGFSSDRYDRIRDFTRNIGIIPISARTGEGIPDLLMILIGLAQRFLEESLKFQVTGPGVGTILEVKEERGLGYTIDTIIYDGEIRVGDTIVIGGREKPYSTKVRALLKPKPNREIRVEERFDRVNKVTAASGVKILAPELEKAMAGSQVRVTKESNVEDIIKEIEQEMEQAKIVTDEVGVMVKADTLGSLEAIVNELREAKIPIGRADVGDISKRDIINAETVNDPMYRVMLGFNVTILPDANDYLQTTDIKIFNSDVIYHLIDDFRKWETEQRALAEKKKFAEIVRPGKVKYLPNCTFRQSKPAVIGLQIMGGMLKPGVTLIKPDGSKIGVVRQIQERNENISIATVGKEVAVSIDGPTAGRQINEGEIYFVDVPEGHSKVLEFQLKDTIKQDELETLMEFLAIKRKDNPFWGR
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: MASZ_RHOFA
Sequence: MTDRVQAGGLQVAKVLFDFVEKEALPGTDLDSEAFWAGAASVIADLAPKNKALLAVRDEIQGKVDAWHGEHAGAEYDRAAYKAFLKEIGYLLDEPADFQIHTSGVDTEITTTAGPQLVVPVLNARFAINASNARWGSLYDALYGTDAIPETDGAEKGTSYNKVRGDKVIAFARDFLDEALPLSSGSHVGTTGYVVDAASLTVTLADGSTVGLKDPSQLLGYQGTPDAPTAILFVHNGLHFEIQIDPESPIGKTDGAGVKDVLLESAVTTIMDFEDSVAAVDADDKVLGYRNWLGLMKGDLTEEVSKGGKTFTRAMNKDRTYTSVDGSELTLHGRSLLFVRNVGHLMTSDAILDADGNEVPEGILDALFTSLAGLHSLTPDNVLSNSRTGSLYIVKPKMHGPDEVAFTAELFGRVEQVLGLPTNTLKVGIMDEERRTTVNLKACIQAASERVVFINTGFLDRTGDEIHTSMEAGPVVRKGAMKGEKWIAAYEDFNVDTGLAAGLQGKAQIGKGMWAMPDLMHDMLEQKIGHPKAGANTAWVPSPTAATLHALHYHKVDVFARQHEIAKAKRATVDEILEIPLAPSTDWTDEEKQNELDNNSQSILGYVVRWIDHGVGCSKVPDINDIALMEDRATLRISSQFIANWLRHGIVTEEQVRESLKRMAPVVDRQNASDPTYKPLAPDFDTNIAFQAASDLIFQGTSQPNGYTEPILHRRRREYKAVNA
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH2_CAEEL
Sequence: MSENIPDIDPNELLPNAPGQHQDLGVDNPPEPDNASIRAERGSPTPSSVTVDNAPSLPDRSFSHLPINDPFSGEIPEVPIPSSAISISSQALSDPVPTPSDTSRPGILRNDEQGSTSSHPVDPQEPNEVNNEYLAHLLDLGFDEYTAVLALKRTNSAGVEQAVAWIVERSNESDFDEDSSSSENEADEEMGAVQSVAGRTHKMVLVANMSLKMGTGKIAAQVGHATLGVYRQAMNSENGQNAIAAWTRHGQVKIVVKGQSTEQLMDLCKVAKDAGCYYYLVQDAGYTQIPAGSRTVLGIFGTVEQVDSVTGGLKLL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Probable peptidyl-tRNA hydrolase 2, PTH 2.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
Protein: GCSPB_BACC7
Sequence: MKNQDQALIFEVSKEGRIGYSLPKLDVEEVKLEDVFESDYIRVEDAELPEVSELDIMRHYTALSNRNHGVDSGFYPLGSCTMKYNPKINESVARFAGFANIHPLQDEKTVQGAMELMYDLQEHLIEITGMDTVTLQPAAGAHGEWTGLMLIRAYHEANGDFNRTKVIVPDSAHGTNPASATVAGFETITVKSNEHGLVDLEDLKRVVNEETAALMLTNPNTLGLFEENILEMAEIVHNAGGKLYYDGANLNAVLSQARPGDMGFDVVHLNLHKTFTGPHGGGGPGSGPVGVKADLIPYLPKPILEKTENGYHFNYDRPEAIGRVKPFYGNFGINVRAYTYIRSMGPDGLRAVTEYAVLNANYMMRRLAPFYDLPFDRHCKHEFVLSGRRQKKLGVRTLDIAKRLLDFGYHPPTIYFPLNVEECIMIEPTETESKETLDGFIDKMIQIAKEVEENPEVVQEAPHTTVIKRLDETMAARKPVLRYEKPAPVQV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: CHS1_BOTFU
Sequence: DVLFARTMHGVFKNIEFMCTRKDSKTWGKDAWKKIVVCVVSDGRAKINPRTRAVLAGLGVYQDGIAKQQVNGKDVTAHIYEYTTQVGISLKKDIVTLTPKQQPVQLLFCLKEKNQKKINSHRWFFQAFGRVLDPNICVLLDAGTKPGKDSIYHLWKAFDLEPHCAGACGEIKAMLGPGGKNLVNPLVAT
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 1, Chitin-UDP acetyl-glucosaminyl transferase 1, Class-I chitin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class I subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THID_MYCBO
Sequence: MNYLPLAPPGMTPPRVLSIAGSDSGGGAGIQADMRTMALLGVHACVAVTAVTVQNTLGVKDIHEVPNDVVAGQIEAVVTDIGVQAAKTGMLASSRIVATVAATWRRLELSVPLVVDPVCASMHGDPLLAPSALDSLRGQLFPLATLLTPNLDEARLLVDIEVVDAESQRAAAKALHALGPQWVLVKGGHLRSSDGSCDLLYDGVSCYQFDAQRLPTGDDHGGGDTLATAIAAALAHGFTVPDAVDFGKRWVTECLRAAYPLGRGHGPVSPLFRLS
What is the function of this protein?
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
What are the official names of this protein?
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, Hydroxymethylpyrimidine kinase, HMP kinase, Hydroxymethylpyrimidine phosphate kinase, HMP-P kinase, HMP-phosphate kinase, HMPP kinase.
What is the protein family that this protein belongs to?
Belongs to the ThiD family.
Protein: DAPF_BRASO
Sequence: MSPLANHSFVKMNGIGNEIVVLDLRDVKHVVTPDEARAVASRVPYDQMMVLQRPRFDGTEAFIRIYNNDGSESGACGNGMRCVVSQVFGKTGQTSATFETRAGLLNCWQGPAPDLYTVDMGVPRFGWQDIPLAEEFRDTRYIELQIGPIDAPILHSPSVVSMGNPHAVFWVDNDVNSYDLERFGPLLENHPIFPERANITLAQIVDRDHITMRTWERGAGLTRACGSAACATAVAAARLKRANRLVHMTLPGGELTIEWRERDDHVLMTGTATFEFEGRFEPALFASVA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBN_SALPC
Sequence: MELIFLGTSAGVPTRSRNVTAILLHLQHPTQPGVWLFDCGEGTQHQMLNTAFHPGKLERIFISHLHGDHLFGLPGLLCSRSMAGPPHPLTVYGPQGVREFIATTLRLSGSWTDFPLQIEEISAGDILDDGLRKVTAFRLEHPLECYGYRVVEHDKPGALNARALKAAGVTPGPLFQALKAGKTVTLADGRQINGADYLAPAVAGKSVAIFGDTAPCEAALALAQGVDVMVHETTLDASMEEKANARGHSSTRQTATLAREAAVGRLIMTHISSRYDDKGCQRLLAECRAIFPATELAYDFSVFPV
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.
Protein: SHO1_YARLI
Sequence: MRQPFSYRPQFQLGLLMGDPFALSTISLGIIGWIIALGGSIGASDQFKNFGWWGLAFEFFVILCVFLVVATDSVEPYRQMLLAFLALATMYVTNSTNNVVYNGTSASSASGAGHILLSIINFLWMIYFGTTHEAGIHAWVDSFAADKGHSYNNDQFAMRRSNPFSLHDQQRQSLGVPGRPVSAYSAGMGGVANYNGLQLGGFENSSNAEPHQASPAFSQQQQQQTATPQQATDSLFVATEYPYRARAVYAYQANPEDANEISFDKGEILDVSDISGRWWQARRDNGEIGICPSNYVELLA
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TU94_GEMSP
Sequence: MGFYMLLTVALLLTSLMNVEATPVDQAERSALEKSGLGNRIQPRYDNCGDAEADCYQSKCMDGETYDEECEASCNYVVANCI
What are the official names of this protein?
Turripeptide IX-04.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRB_ANAD2
Sequence: MIGRHKHCIALEDFSREEILEVIDLAASMKEVLQRPIKKVPSLRGKMVVNLFFEASTRTRSSFETAAKILSADALNWTSSSSSVTKGETLVDTAKNLEAMRPDVLVIRHSAGGAPRLVAEHVGCSVVSAGDGAHEHPSQGLLDCFTLREKLGTLEGKTVAIVGDVSHSRVARSDLHAFPKLGAKVRLCGPPTMMPAGVERLGATVHTDLREAVDGADAVIMLRIQHERIGDPLIPGTREYSKVWGLNAKKAADWLKPSCVILHPGPINRGVELSPEVADGPRSVILDQVQNGVAVRMAILYLLAGGAGEEARA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.