PharMolix/UniProtQA huggingface dataset:
Protein: Y319_MYXXA
Sequence: METFPSVGSPGLWAGFIAFVIAMLALDLGVFHRKAHVVKFKEALGWSALWVSLALVFGAGVWWKFGPEPGLQFITGYLIEKSLSVDNIFVFVVIFSALRIPALYQHRVLFWGILSALALRAIMIFAGVAMLARFHWLIYVFGGFLIITGVKLFLQRNKEDNPEEGALMRLARRTIPSTPNFDGHHFFTVENGRKLATPLLMALLLVEASDILFALDSIPAIFAVTTDPFIVFTSNIFAILGLRSMFFMLAGAVEKFSYLKVGLSAVLVFVGTKMAIIDFVKMPPEVSLSVIAGLLGASIVASLIKSRHAPTSDADAPKV
What are the official names of this protein?
Uncharacterized membrane protein STKORF319.
What is the protein family that this protein belongs to?
Belongs to the TerC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBL_GLOVI
Sequence: MSYTKTQAKAGYQAGVKDYRLTYYTPDYTPKDTDVLAAFRVTPQPGVPIEEAGAAVAAESSTGTWTTVWTDGLTELDRYKGRCYDIEPVPGEDNQWICYIAYPLDLFEEGSVTNVLTSLVGNVFGFKALRALRLEDIRFPIALVKTYQGPPHGIVVERDKINKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSQPFMRWRDRFLFVQDAIVKSQAETGEIKGHYLNCTAGTCEEMMERAEFAKELKTPIIMHDYLTGGFTANTTLAKWCRRNGILLHIHRAMHAVIDRQKNHGIHFRVLAKCLRLSGGDHIHTGTVVGKLEGERASTMGFVDLLREEHVERDLSRGIYFTQDWASMPGVMAVASGGIHVWHMPALLDIFGDDAVLQFGGGTLGHPWGNAPGATANRVALEACVKARNEGRDLMREAGDIIREAARWSPELAAACELWKEIKFEYEAVDKL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: YET1_YEAST
Sequence: MSLYFTTLFLLLTVEMVMLFIFVLPLPFRIRRGIFSTYNQLTAKQQIKTIIFITGCLVGLLFIDSWKRSQIRVSLYHNDNSGSIGSSAVTPIQALASRAYNQRNMYISGFILYFSICIPTVMSIVKRLVKYQGLINEQEKQKLNKPSSNSKKDSNEADSTKLQEELRKKQISLEGLQKQVKNLEKYFDEKNQPGNVAAAEASKKGN
What is the function of this protein?
May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
What are the official names of this protein?
Endoplasmic reticulum transmembrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the BCAP29/BCAP31 family.
Protein: FERA_PARDE
Sequence: SRLPPATRDKLADEITFFPA
What is the function of this protein?
Reductase activity that acts on Fe(3+)-chelates and NADH as an electron donor and requires the presence of FMN for full activity.  May play a role in iron uptake.
What are the official names of this protein?
Ferric reductase A.
Protein: ISPT_DEIRA
Sequence: MASLNSALRTAQHVRTATRGALLWGYEQKLAREVKANGKLPRHLGLILDGNRRFARAAGLQREMGHSFGADKAHEVLQWCLELGIPSATIWVLSTDNGSREPAELAHILSLLEREARQLAVDPRIHANRVRVRAIGQHDNFPPQVLAALNNLEESTAGYEGMRLNIAVGYGGREEIVDAVQSYLRTQAAQGATLEQAAENLTPDAIGAHLYAADQPDPDFIIRTSGEIRLSGFMLWQSVYSEYYFCDVYWPGFRRVDFLRALRDFQGRDRRFGK
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: CPPC_NEIGO
Sequence: MIVQFFNRGKGGGSGPIDYLLGKDRDREEARLLRGDPEETAALINSSDYAKKYTAGCLSFEESNIPAEQKHALMDSFEECIFAGLDKDQYNCLWVEHRDKGRLELNFVIPNIELLSGKRLQPYYYAADRGRVDAWRTMQNLTHGYSDPDDPAKRQSMTQAKDLPRNTQEAAQSITEHHRRLRSPSPIRQAKKPRRRAGNAGKGRF
What are the official names of this protein?
Cryptic plasmid protein C.
Protein: MBP_CAROB
Sequence: AGGAHFFGQEGSRKVPEKGKEPATRSVLMAPTLHKAHQAAGRQTDDSAVVHFFKNMMSPKAPVQQKARSGASRAITKFIWGTDGQRPHYGASGSSKSREAYRGRKDGSGTLSSFFKMGKKGEGSPARR
What is the function of this protein?
This protein may function to maintain proper structure of myelin.
What are the official names of this protein?
Myelin basic protein, MBP.
What is the protein family that this protein belongs to?
Belongs to the myelin basic protein family.
What are the subcellular locations of this protein?
Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.
Protein: MDTD_ECOL6
Sequence: MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQIGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAITTLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSKGTGFSPLAIAGLVAVGVVALVLYLLHAQNNNRALFSLKLFRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGFGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMASIIALPAFIFARVPNDTHQNVAISRRKRSAQ
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROE_SULTO
Sequence: MLEINYDTKLLGVVGENISYTLSPAIHNYSFQELGINAVYLAFDIKSDEFKEIFPGLVKIAYGLNITIPYKEIAIKYVEAQSEAKRIGAINTIFNGKGYNTDYIAIKSLVQERIDKFETCTIFGAGGAARAAIFALHDLDCSINVINRSKEKAEKLIEEMRNKNIEIKITYNCKSDIIVNSTPNPDFVPDECVNGKLVIDFVYKPVITSLIKRAQNKNIKTINGIEILVRQAMEAEKIWFGKSLEDEEVVNYLYARKLIW
What are the official names of this protein?
Shikimate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: Y1556_STRPG
Sequence: MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAIREMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK
What are the official names of this protein?
UPF0154 protein SpyM51556.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DDL_FRACC
Sequence: MAGSRRRIRLALLFGGRSTEHAISCISASGVLRALDRDVYDVVPVGIDTHGRWVVLPDDPTALAVTGDRLPAVVAAHGESVVLAADPTTPGLLPCRPRGGLDSVRNTLGSSDALGSSDIPGDIDVVFPLLHGPFGEDGTVQGLLEMAGLPYVGSGVFASAAAMDKQHMKALLRAAGLPVGSYAVLRAGDTLTGADQERLGLPVFVKPARGGSSIGISRVEAWADLDTAIKAARASDPKVLVESAIVGREIECGVLGILDGPGAEASVPAEITVTSSAGFYDFEAKYMSDATHFDVPANLSHAVREEVRGAAIAAFEALDCAGLARVDMFVTADDHVIINEVNTMPGFTPTSMFPRMWEASGVTYPQLVDRLVRLALRDGAGLR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_ACTPJ
Sequence: MKTYTYSKQDLSFIEQLSQAYCKDPFSYLGLHQAGDVSVIRVFLPEATTVKILSADGQILSEALKIDDSGLFVAQLSQQYSSLNYRLRVGYSLAEIDLEDPYRFTSSLLPMDNWLLAEGTHLRPYEILGAHLKTQEGVSGVHFSVWAPNARRVSVVGDFNYWDGRVNPMRFHAESGIWDIFLPNVEKGALYKFEILDSNGNIRLKSDPYAFASQFRPDTASVVTGLPEKIEVDAKLRHANEPDQPISIYEVHLGSWRRHLENNYWLNYEEIANELIPYVKDMGFTHIELLPITEYPFDGSWGYQPTGLYSPTSRFGSPDDLRTLIRKAHEAGINVILDWVVGHFPTDSHGLTEFDGSHLYEHQDPREGYHQDWNTLIFNYGRHEVFNYLSSNALYWTERFGIDGLRVDAVSSMIYRDYSRKDGEWIPNQYGGRENLEALDFLRRTNRMLKKEGHGAVVIAEESTSFAGITHSPTENGVGFDYKWNMGWMNDTLRYMSLDPIYRQYHHDWMTFGMMYQYSEKFVLPLSHDEVVHGKCSILGKMSGDCWQKFANLRAYYGYMWGYPGKKLLFMGNEFAQGREWNYNESLDWFLLGEQGGGWHKGVLNWVRDLNRTYQKYPALYQLDYDPAGFEWLVVDDWQQSVFAFERKAKNGESVIVVSNFTPVVRHNYRIGVRQDGTYTEILNSDAAYYEGSNVGNYGEIECEAIESHGKPFSIELSIPPLSTIFIACQPKPKEAVEAEQDIVKMAEVAMQKALKPTKKTVSVKAKAHKKAHKNKK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RPC3_ASPOR
Sequence: MTSQYAGELCTLLVEDNFGELFARIFSTLNRYDRLSFSRLKFYSRLSNAQLRHGLAAMIQQHLVYHYTSYDDGITYYEPNMQSAYYLVRSGKILELIEHRLGKYAATVMSTIMFLGHAQVGYLETLPALRPSNSDVNRASEERGGIHETEEYHGEEARQETEEHRETEGRPNGLNSDYTSSERPALLHPTLKALAGHGYILRVRDAQFQSYADNALDAERTIKSRPDIKALKGKKLDEAVTEGTLELLKERLDGDLTRGLMFNGVPRGAKRRHTTGATEASNKKARVDYAAVDEDEDGGEENEWSDDDFGEDTIPMESGITVRINYEKLDVALRNRRFLELAERDSSPVTAEVYESLLRRIEYQTAKCRDTTEIPREGEEGEHYSVPVPLRAVVEDVDLFLDLAGSVGPMEVSQPINRRGKRPLEETTNGAAHDGTNGGQSDGNRTYEVDQHLCLLAQPPYSLTSKRMVSGLITWTVEFRHLARKLRHLELERIIEARYGDVALRVVRVLHDKGKLDEKRLQEISLLPFKDLRQVLASMQTGGFVDLQEVPRDALRQPSKTIFLWFYDPDRVGNSVLEDTYKAMSRCLQRLRFERSRLKEFLEKTERSDVKGNEERYLSEAELTLLGQWRAKEALLLGEVARLDEMVAVIRDY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit rpc3, RNA polymerase III subunit C3.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMH_HELPG
Sequence: MMRCVVYSIAKSSPLELVKIYQKQCKQFDCELELVDLFPKNTANAQKVSKELAQKSYSLAFEPYLNPKAKNIALHPKAQRGDSFAFSKMLENHLNINFFIAGAYGFEENFLKGCQAWSLSEMTFSHEVAKIVLCEQIYRALSIIFKHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS25_NEUCR
Sequence: MAPAASGAKKQKKKWSKGKVKDKAQHAVILDKSTSDKLYKDVQSYRLVTVATLVDRLKINGSLARRCLKDLEEKGQIKQVVGHSKMKIYTRAIGADE
What are the official names of this protein?
40S ribosomal protein S25.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: GYP7_DEBHA
Sequence: MPVDKQAKRKKSISSNEVELLYTKSKTYLHPTTSKKDNIPGYLSLSRGANAANRDIIISFMSEKQLSSEELKAYENVDIADLQDDLEALKLGGTNSRSSGKRNLNIVSKPPTSSAFGFCFSIPISFVYSIQVRKPSVGWWFGSIIINTQDGEKLPIVFFHDDESPSTLKNQKVRNQRFDPFGDNGEMYWGGSDFMNALGKFADVQKSSVEPSVYLINPESNDLRNFAPFKEPKTAKTETNQEPFKLPDVNKFFANAKWKVLETVATFSAKTRNQVLDLVDENAPMPIKQIINKPEVQKIGNEFDSARVYLAKWAAQVKEEAEEAHRKYQLDDEIYNKINKELGVGSNTEILTDEEVSKTSRRKPISKVEWEGLFDFSGRLIISIDEIKDRIFHGGLEDCIRGEAWLFLLNVYPWDSSAEERKTLRNSFQTAYEEIKLKWVNDDDKRSVDFWKDQKHRIEKDINRTDRNLSIFQNKKKISISGVGSDRLPTTRESSPETPDEADDDEFDVSNITNPHLFKMREILLTYNEHNVNLGYVQGMTDLLSPLYVTFQDESLTFWAFVNFMDRMERNFLRDQSGMKNQMLTLNELVQFMLPDLFKHLEKCESTDLYFFFRMLLVWFKREFEWSSVLSLWEILWTDYYSGQFHLFFALAVLSDNERIIRQNLSRFDEVLKYMNDLSMNMNLNHLLIRAELLFLRFRRMIDIIDRENSLKKLNNPGVYDDANNSLIKISPALRELLSKKPVIQKETERPEGVGGG
What is the function of this protein?
Most effectively accelerate the intrinsic GTPase activity of YPT7.  It is also active, but to a lesser extent, on YPT31, YPT32 and YPT1.  YPT6 and SEC4 (By similarity).
What are the official names of this protein?
GTPase-activating protein GYP7, GAP for YPT7.
Protein: ARGC_BACFR
Sequence: MIKAGIIGGAGYTAGELIRLLINHPETEIVFINSTSNAGNKITDVHEGLYGECDLTFTDELPLEDIDVLFFCTAHGDTKKFMESHNIPEELKIIDLSMDYRIASPDHDFIYGLPELNRRATCTAKHVANPGCFATCIQLGLLPLAKHLMLNEDVMVNAITGSTGAGVKPGATSHFSWRNNNMSVYKAFEHQHVPEIKQSLKQLQNSFDAEIDFIPYRGDFPRGIFATLVVKTKVALEEIVRMYEEYYAKDSFVHIVDKNIDLKQVVNTNKCLIHLEKHGDKLLIISCIDNLLKGASGQAVHNMNLMFNLEETVGLRLKPSAF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_PELUB
Sequence: MKKGKKLYEGKAKIIYATSDKNLVIQYFKDDATAFNNLKKSTIEGKGVLNNRISEHILSNLTQIGIKNHLVKRLNMREQIIKLVEIIPIEFIVRNVATGSITKRLGIEDGTVLKQPLLEYCLKDDKLGDPLIAEEHILAFDWATKSELEKVKKMILRINDFMIGMFRGVGIKLIDFKLEFGRLKENGKNEVILADEISPDTCRLWDSITDKKLDKDRFRKDLGDLIPAYTEVAKRLGILHEQSNLSAVNVTKLRSVKKRK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PUR9_AGRRK
Sequence: MAVVSKKIPAPDKVQVKTALLSVFDKTGIVELARALSEKGVRLLSTGGTHKAIAAAGLAVTDVSEVTAFPEIMDGRVKTLHPKVHGGLLAIRDDAEHQAAMKEHGIEGIDLAVINLYPFEDVRKAGGDYPTTVENIDIGGPAMIRASAKNHAYVTTLTDPADYSELLEQLSADAGQTTYDFRKRMAAKAFARTAAYDAMIANWFAEALDIATPRHRVIGGVLREEMRYGENPHQKAAFYVTGENRPGVSTATLLQGKQLSYNNINDTDAAYELVAEFLPENGPACAIIKHANPCGVATGPSLVEAYKRALACDSVSAFGGIIALNSILDAATAEEIVKLFTEVIIAPEVTEEAKAIIARKPNLRLLSVGALPDPRVAGLTAKTVSGGLLVQNRDNALVEDMELKVVTKRAPTAQELEDMKFAFRVAKHVKSNAVVYAKDGQTAGIGAGQMSRVDSARIAAIKAEEAAKAMGLAEPLTRGSAVASEAFLPFADGLLSAIAAGATAVIQPGGSMRDQEVIDAANEHNVAMVFTGIRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RL14_CAMLR
Sequence: MIQSFTRLAVADNSGAKELMCIKVLGGSKRRYATVGDVIVASVKKALPNGKVKKGQVVKAVIVRTKKEIHRDNGSLIRFDENAAVILDAKREPIGTRIFGPVGREVRYGGFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RPIA_BURA4
Sequence: MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSVATTERLKSHGIKVFDLNEIESLQVYVDGADEIDASGAMIKGGGGALTREKIVASVADTFVCIADGSKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVLRVTQDGAPYITDNGNEIIDVKGLQIVDPRGFEAQINAWPGVVTVGLFAERGANLCLLGTPNGVETIVYPG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: CEP19_XENTR
Sequence: MSYMAKKCGVRFQPPAIILVYEDKEAGKSRQRIMPIRNFSKYSDCSRAAEQLKNNPRHKDYLDLVSLRQLEKLYKLLKGHLKGESLKVTLEEIKKEETIDPEEDLNKLDDKELAKRKHVMDELFEKNRKKKDDPDFEYEIEVDFTKDEQAESCGWDDASDEGF
What is the function of this protein?
Required for ciliation.  Recruits the RABL2B GTPase to the ciliary base to initiate ciliation.
What are the official names of this protein?
Centrosomal protein of 19 kDa, Cep19.
What is the protein family that this protein belongs to?
Belongs to the CEP19 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, cilium basal body. Note=Associates with the mother centriole in early interphase. Localizes to spindle poles during mitosis, and to distinct foci oriented towards the midbody at telophase. Localizes slightly apical to the subdistal appendage on the mother centriole, but below the distal appendage.
Protein: EHN3_CAEEL
Sequence: MEKCDICHQKFSNKTNLNRHKVMHSGKKKFECQFCRRPFFRNDRMKEHMMTHIKKGNTFECPITACNSKFNSFTSLQFHVDSEHIIRGSSPAKCKSCIKWFNSSHRLLLHFHTAHLDHTKFFSFKPAPILPKSTTSILNPIKNPDDFDRIFDFFKTEIAPLFPLHSTVSQAPLPQCSRSVKSAKELSPTPSTEIETPEEEELDGPESWYCDYCKIRFDDKVMWYLHSGLHSDDIPFKCSLCGSLCDGKYDFAAHLVYANHNF
What is the function of this protein?
Required for proper gonadal primordium assembly and somatic gonad precursor cell morphology.
What are the official names of this protein?
Zinc finger protein ehn-3, Enhancer of hand mutation protein 3.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS12_RENSM
Sequence: MPTINQLVRKGRSPKVAKTKAPALKNNPMRRGVCTRVYTTTPKKPNSALRKVARVRLAGGIEVTAYIPGVGHNLQEHSIVLVRGGRVKDLPGVRYKIVRGSLDTQGVKNRKQARSKYGAKMEKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PLSY_MYCGE
Sequence: MNQASAIAILVIFSLASGYLLGSIIFADIFSKILKKNVREFGSKNPGATNSMRVFGLKIGFLVAIFDAFKGFFAFLLTWILFRFGLQGYLTEKVYQSTYFLSYLSCFAATIGHIFPLYFKFKGGKAIATTGGSLLAISLWWFLICLLIWIMITLITKYVSLASLITFFVLAVIILIPWLDYLYFFNSDPLKSITYQNEWYIILFFCLWYWPLTVVVFWLHRANIIRILHGKESKITQLN
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMC_BUCCC
Sequence: MNKTVIKTFQISKEYKILKKNFQLFKNKTTIISGIIPSVFLKINIIKRFIFYVNYFNLYLKILKKNSKNVIFNNFNHKNKLSSYKQLIFFLTKNKKEFKLHLTFLLSHISKTCVIYVVGEKKCGINSISKIFSNYLIFKKIDYARTCSLYKAKIMKLPKFYLHKFINIYIWNNITIQSLPGVFGYKKIDTGSKLLISTFNKKINGKILDIGSGTGILSIALAKKNPLIKITLTDIYDAAIWCSKNNLIKNNLIGKVLFSDIYSHIKKRYDLIISNPPIHYNLKINLKILKKIIKNSKKHLKKKGELRIVISSFISLKYIINFNKINFKILLKNKSYTVIQITN
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PSEE4
Sequence: MKLNDLSPAPGSRREKHRPGRGIGSGLGKTGGRGHKGQTSRSGGSIAPGFEGGQQPLHRRLPKFGFVSLKAMDRAEVRLSELAKVEGDLITVQSLKDANVIGQHVQRVKIMLSGEVTRAVTLKGIAVTKGARAAIEAAGGKFEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: TPIS_STRMK
Sequence: MRRKIVAGNWKLHGSRQFANELLGQVAAGLPLEGVDVVILPPLPYLGELVEDFGETGLAFGAQDVSSNEKGAYTGEVCAAMLVEVGARYGLVGHSERRQYHHESSELVARKFAAAQHAGLVPVLCVGETLEQREAGQTEAVIASQLAPVLELVGAAGFAQAVVAYEPVWAIGTGRTATKEQAQQVHAFIRGEVARIDARIADSLPIVYGGSVKPDNAGELFAQPDVDGGLVGGASLVAADFLAIARAAAAN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PS18_PINST
Sequence: SLSIMEPIR
What are the official names of this protein?
Putative acid phosphatase PS18.
Protein: RPOZ_MAGMM
Sequence: MARVTVDDCVQHVSNRFELVILAAKRARQLAKGAEPEVSVDRDKNTVVALREIAESKLNMDDLRRMEETVVEEEVVDEVIRFEIADLAVSDDLADGDAANDLQGEEDDLGLGLDEAEDLGF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: DCUP_ECOSE
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_CAEBR
Sequence: MGIKGLSQVIADHAPSAIKVQEIKAFFGRKVAIDASMCLYQFLIAIRQDGSQMQSEDGETTSHLMGMFYRTIRMIDNGIKPVYVFDGKPPDMKSGELEKRTERRAEAEKALTEAKEKGDAKEAEKFERRLVKVTKQQNEEVKQLLGLMGIPVVEAPCEAEAQCANLVKAGKVYGTATEDMDALTFGSCVLLRHLLAPEAKKIPIKEFHLARVLEEMQLTKDQFIDLCILLGCDYCGTIRGIGPKKAVELIKQHKNIETVLENIDQTKYPPPADWPYKRARELFHEPEVMKCDEVELTWKDPDVEGIVKFMCGEKNFSEDRIRSAMVRMQKSRNAGTQGRIDSFFTVSSQVKCVTVAKRKAQEEAEKMKKGGKKSGPPKKKAK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Cell death-related nuclease 1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.