PharMolix/UniProtQA huggingface dataset:
Protein: PDFR1_CAEEL
Sequence: MADATSPFNVSILDNSTKLSEMVESGWNVLASTSVQAFNEAMDVLEESYPLCKKMLDHNNLFPERDPNDTRIWCNATYDTVLCWPPTPANSSVTLQCPHMKGLDPNKNITKDCHVSGVWSGRNAGEMGPTLPGWTNFTMCYTDEVIYIMQNLNNESLTIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFKTVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIAGYGIPLVHTMLWLLVVLIKKDFKVERCLGSYYLEPEFWILDGPRMAELVINLFFICNVIRVLYSKVRESNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNIMVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYARYRLLHKSQNELRRGSRSVASHYAAKNGTANASAPQTNNADEFGKLSPFPSRSKKGSDDSTTKLMKDAVMEEEKNANNNGYGSAGEMTPLREGSNRSTKSP
What is the function of this protein?
G-protein coupled receptor which is activated by neuropeptides PDF-1 and PDF-2; however, activation is lower compared to isoforms a and b (PubMed:18390545).  Probably inhibits cAMP levels through the G-alpha(i/o) type of G proteins (PubMed:18390545).
What are the official names of this protein?
Calcitonin receptor-like protein 1, Pigment dispersing factor neuropeptide receptor homolog 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FARB_CALVO
Sequence: PDNFMRF
What are the official names of this protein?
CalliFMRFamide-11.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YJB5_YEAST
Sequence: MRHVKRKSLVLGWKYIISHKIISGYIWLYRNCTTNIYTVCKFLRCGYICEELCNGRSTCDDRTFAHRTFVFMGVYLQLIHHISRFRTNIAFITQ
What are the official names of this protein?
Putative uncharacterized protein YJL015C.
Protein: DEFI_APIME
Sequence: MKIYFIVGLLFMAMVAIMAAPVEDEFEPLEHFENEERADRHRRVTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKGVCICRKTSFKDLWDKRFG
What is the function of this protein?
Found in royal jelly and in hemolymph, potent antibacterial protein against Gram-positive bacteria at low concentration.
What are the official names of this protein?
Defensin-1, Royalisin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSP83_IPONI
Sequence: MADVQMAEAETFAFQAEINQLLSLIINTFYSNKEIFLRELISNASDALDKIRFESLTDKSKLDAQPELFIRLVPDKTNKTLSIIDSGVGMAKADLVNNLGTIARSGTKEFMEALQAGADVSMIGQFGVGFYSAYLVAEKVIVTTKHNDDEQYIWESQAGGSFTVTRDVDGEQLGRGTKITLFLKEDQLEYLEERRIKDLVKKHSEFISYPIYLWTEKTTEKEISDDEDDEPKKEEEGDIEEVDEDKEKEGKKKKKIKEVSHEWQLINKQKPIWLRKPEEITKEEYASFYKSLTNDWEDHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDTRKKMNNIKLYVRRVFIMDNCEELIPEYLGFVKGVVDSDDLPLNISREMLQQNKILKVIRKNLVKKCIEMFNEIAENKDDYNKFYEAFSKNLKLGIHEDSQNRAKLADLLRYYSTKSGDELTSLKDYVTRMKEGQKDIYYITGESKKAVENSPFLERLKKKGYEVLFMVDAIDEYAVGQLKEYDGKKLVSATKEGLKLEDDDEEEKKKREEKKKSFENLCKIIKDILGDKVEKVVVSDRIVDSPCCLVTGEYGWTANMERIMKAQALRDSSMSSYMSSKKTMEINPDNGIMEELRKRAEADKNDKSVKDLVLLLFETALLTSGFSLDDPNTFGARIHRMLKLGLSIDEEEAGDDADMPALEEEAGEESKMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 83.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSD_ALIF1
Sequence: MSLVYGLVVNGPAYGSQASRKAFQFAEAVLAQGHSIKKVFFYQEGVLNASSLILPANDEVDITKQWQELALRHDIELETCVAAALRRGVIGEEEASQHQLKQHNLAVGFQQAGLGGLATALLKFDRVVQF
What is the function of this protein?
Could be part of a sulfur-relay system.
What are the official names of this protein?
Sulfurtransferase TusD homolog.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBG5_RAT
Sequence: MSGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFRPQKVCSFL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
Protein: RS17_AYWBP
Sequence: MQRNFRKTFVGKVVSDKMDKTITVIVDIYKKDPLYGKRVKQSKKFHVHDENQEAKPGDLVNFMETRPLSKTKRFRLFKILYHSKSAN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NQRF_HAEI8
Sequence: MSDSVILALGIAAFTVIVLVLVAIILFAKSKLVDSGDITIDINDDPEKAITLPAGGKLLGALASKGIFVSSACGGGGSCGQCIVKVKNGGGEILPTELSHINKREAKEGYRLACQVNVKGNMEVELPEEIFGVKKWECTVISNDNKATFIKELKLAIPEGEEVPFRAGGYIQIEAEPHVVNYKDFDIPEEYHEDWDKYDLWRYVSKVDEHIIRAYSMASYPEEKGIIMLNVRIATPPPRQPDAPPGQMSSYIWSLKAGDKVTISGPFGEFFAKETNAEMVFIGGGAGMAPMRSHIFDQLKRLHSKRKMSFWYGARSKREIFYQEDFDQLQAENPNFVWHVALSDALPEDNWTGYTGFIHNVLYENYLKNHEAPEDCEYYMCGPPVMNAAVIKMLKDLGVEDENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ANTDA_ACIAD
Sequence: MTARNLAEWQNFVQGCIDFRPNDGVYRIARDMFTEPELFELEMELIFEKVWIYACHESEIPNNNDFVTVQIGRQPMIVSRDGKGELHAMVNACEHRGATLTRVAKGNQSVFTCPFHAWCYKSDGRLVKVKAPGEYCEDFDKSSRGLKQGRIASYRGFVFVSLDTQATDSLEDFLGDAKVFLDLMVDQSPTGELEVLQGKSAYTFAGNWKLQNENGLDGYHVSTVHYNYVSTVQHRQQVNAAKGDELDTLDYSKLGAGDSETDDGWFSFKNGHSVLFSDMPNPTVRPGYNTVMPYLVEKFGEKRAEWAMHRLRNLNLYPSLFFMDQISSQLRIIRPVAWNKTEVISQCIGVKGESSEARRNRIRQFEDFFNVSGLGTPDDLVEFREQQKGFQGRIERWSDISRGYHQWTYGPTQNSQDLGIEPVITGREFTHEGLYVNQHGQWQRLILDGLNKKALKMHDVTFDNQSVMDEV
What is the function of this protein?
Component of anthranilate dioxygenase multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into anthranilate to form catechol.
What are the official names of this protein?
Anthranilate 1,2-dioxygenase large subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: MIAA_BUCBP
Sequence: MIVKFEKFEKLKKPLVIFLMGPTACNKSLLAMTLKDILPIELVSVDSALIYRGMDIGTAKPSNMELLKYPHFLVNIRDPLQTYSVGEFYKDILKIIDYIHSINKVPLLVGGTMFYFKILLTGGLSNLPSSNDNIRKYLLTLLQKKSKFFLFNQLKSIDPISAERIHFNDVQRVLRALEVFFISGKTLTELCRLKNFVSPYNIVQFSLMPESKEWLFNKITIRFKKMLSCGFEYEVKKLFNRGDLHKNLPSIRCVGYRQMWDYFMHNLTYDDMICESLKATKRLVKSQLTWLNNWKKLNVLSSSDTLKNLITKIISVINANIFV
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: AROE_AGRRK
Sequence: MGDSRETHGLNAFVTGYPVKHSRSPLIHGYWLRTLNLAGSYRAVEVTPDDFPAFIAALKDRSSGFVGGNVTIPHKEIAFKLADRPDELSEELGASNTLWLEDGLLHATNTDGRGFTANLDECHPGWDRTDRAVILGAGGASRAVIQAVRDRGVNEIHVVNRTVERAQELSDRFGAQVHAHPMAALGEVMRSAGLFVNTTSLGMENEVAPTIDFSPLAENAVVTDIVYVPLKTPLLAQAEEQGFATVDGLGMLLHQAAPGFETWFGKRPVVDEVLRALIIADMDKHR
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: PA_I80A4
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSERGEETIEEKFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGCIEGKLSQMSKEVNAKIEPFLKTTPRPIKLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYIVKPHEKGINSNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDNCRDISDLKQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEYIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQMSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPNGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: DEF87_ARATH
Sequence: MTTKKTSSVVLPLLLVFALILMPMVAGQLKSTCRIAEAWKGAKECNAKCAALGTTRGGVCQKFLGDLYCCCWD
What are the official names of this protein?
Defensin-like protein 87.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3C_DROWI
Sequence: MSRFFANGSDSESESSEEEVQAPNFNKATAFQFSDDEEEVKRVVRSTKEKRYENLTAIIKSIRNHKKIRDISNTLTSFEDLTKAYQKALPVISKEENGITPRFYIRCLAELEDFINEVWEDRDGRKNLSKNNAKSLGTLRQKVRKYIKDFEDDLSRFRENPQEESENEDEEAAAHDSDGGLDAGSDIEKREPTVAATKLAKSVPSKLPVADDEDSDESIDWDPDTESETESSEDENQYQNMRERFLKRSTEKDDKDDDKRKDKRKEQKIKLRKRAEDEDGEGWETVVKGHVVEKPKMFEKDAEIDIPLVLAKLLEIMSARGKKRTDRRLQIDLLFELRDISDQHELGVPISVKIHFNIISAIFDYNQKISEPMKLEHWALLLEVMQSMMKLLLANPDIQLSESVAEEHEEYNATPYLIRGCPLAAVERLDDEFTKLLKECDPHSNDYVSRLKDEINVVKTIELVLQYFEVNGSNNERCRIYLRKVEHLYYKFDPEVFKKKRGDIPNTTQTSVDIMDRLCKFIYAKDDTDRIRTRAILTHIYHHAMHDNWFQARDLILMSHLQDNIDAADPSTRILYNRMMANLGLCAFRQENVKDAHHCLVDLMVTGKAKELLAQGLLPQRQHERSAEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVRDMLVKFIKEESLRTYLFTYSNVYTSISIPSLAEMYELPVQKVHSIISKMIINEELMASLDDPSETVVMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQNNQGGNWGGQRRDNRNQRNRNQRGHHKNQQNQNQQQQQQHQREQQQVQTIDEE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4CL3_ARATH
Sequence: MITAALHEPQIHKPTDTSVVSDDVLPHSPPTPRIFRSKLPDIDIPNHLPLHTYCFEKLSSVSDKPCLIVGSTGKSYTYGETHLICRRVASGLYKLGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTANPFYTSQELYKQLKSSGAKLIITHSQYVDKLKNLGENLTLITTDEPTPENCLPFSTLITDDETNPFQETVDIGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLKSNDVILCVLPLFHIYSLNSVLLNSLRSGATVLLMHKFEIGALLDLIQRHRVTIAALVPPLVIALAKNPTVNSYDLSSVRFVLSGAAPLGKELQDSLRRRLPQAILGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRLSLGYNQPGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHHSIADAAVVPQNDEVAGEVPVAFVVRSNGNDITEEDVKEYVAKQVVFYKRLHKVFFVASIPKSPSGKILRKDLKAKLC
What is the function of this protein?
Produces CoA thioesters of a variety of hydroxy- and methoxy-substituted cinnamic acids, which are used to synthesize several phenylpropanoid-derived compounds, including anthocyanins, flavonoids, isoflavonoids, coumarins, lignin, suberin and wall-bound phenolics (PubMed:10417722).  Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioesters (By similarity).
What are the official names of this protein?
4-coumarate--CoA ligase 3, 4CL 3, (E)-ferulate--CoA ligase, 4-coumarate--CoA ligase isoform 3, At4CL3, 4-coumaroyl-CoA synthase 3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: 14332_SOLLC
Sequence: MAREENVYMAKLAEQAERYEEMVQFMEKVSTSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVKCIKEYRSKIESELSDICDGILKLLDSNLIPSASNGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLSAYKAAQDIANTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQDDGADEIKETKNDNEQQ
What are the official names of this protein?
14-3-3 protein 2.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: RS3A_LEIBR
Sequence: MALGKNKRISKGGKRGKRGKAQETMARKEWYDVVAPSNFEKRQFSKTICNKTQGTRIAADVLRGRVFEANLADLNQSAGEEEAYRKVRFTVQEVQGRNLLTQFHSMEMTTDKMASLLRKWCTTMETTVEVRTADGYTMRLFVVAFTKPQANQQSRNCYAKQRLVKWLRMRVTKMIKRRLSKVQIKEAVSLLTRNVLSDALVRRCNPIVPLREMRIRKVRVVRTPKFDAQALLNAHGTIPTSVEADPREVEEAVEAAPAAAKAAE
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_STAAN
Sequence: MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: G6PI_BACCN
Sequence: MSTHVTFDYSKALSFISEHELTYLRDAVKVSHHAIHEKTGAGNDFLGWVDLPLAYDKEEFIRIQKCAEKIKNDSDILLVIGIGGSYLGARAAIEMLNHSFYNMLSKEQRKTPQVLFVGQNISSTYMKDLMDVLEGKDFSINVISKSGTTTEPAIAFRLFRKLLEDKYGKEEARKRIYATTDKARGALKTLADEEGYETFVIPDDVGGRFSVLTPVGLLPIAVSGLSIEEMMQGAAAGCNDFAKSELEENPAYQYAVVRNALYNKGKTIEMLVNYEPALQYFAEWWKQLFGESEGKDQKGIFPSSANFSTDLHSLGQYIQEGRRDLFETVLKVGKPTHELTIELDESDLDGLNYLAGKTVDFVNTKAYEGTLLAHSDGGVPNLIVNIPELNEYTFGYLVYFFEKACAMSGYLLGVNPFDQPGVEAYKKNMFALLGKPGFEELKAELEERLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_THEP3
Sequence: MKNVGIISLGCPKNTVDSEKMLAILKEKGYNIVNDKNKADILIINTCGFIEDAKRESIEYIIEMGKLKNRRLKYLIATGCLSERYNKELLKELPELDAVIGTGDFPKIAEVIEEIEKGKTVLEYGHANLLNDEGIQRILTTPNYYAYLKIAEGCSNACSFCIIPKIRGRYRSRKMEDILREAEELVKKGAKELILIAQDTTKYGVDVYKKFMLPQLLKEISKIDGLKWIRLLYAYPDSVTEELVEEIKNNEKIVKYIDIPLQHSHDEVLKRMNRNTNRQKIEEVISRLRSIPNMVIRTTFMVGFPGETEEEFEDLKQFIKEKRFERVGVFTYSREEGTKSYYMKPQIKKSVKIKRQQELMEIQKEISYQHNLSKVGKQLEVLIEGFEDGIYYGRSYMDAPEIDGVVYVKSNKKLKAGDFVVATITDAYEYDLVGEY
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUMA_CONCL
Sequence: MMSTKGITLFLCLLLLALATSVNGGQGTRRSRMTRALHGGRPSARYDAPYCSQEEVRECHDDCSGNPVRDACQCAYDPAGSPACDCYCVEPWRR
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal22a, Conotoxin Cl-S1.
What are the subcellular locations of this protein?
Secreted.
Protein: DNLJ_AMOA5
Sequence: MDKEQARKEIKRLTALVAYHNKLYYEEAQPEISDYEFDQLLEKLIALENQFPDLRLPNSPTQRVGGEPSKKFATVYHQYPMLSLSNTYSAEEVMQFVKRAHKQLPGATIEFFCELKFDGVAISLLYKEGKLDKVVTRGDGFKGDDITENAKQIPNIPQIIEHKDLPPAFEVRGEAFMSLADFEKLNRDRLAHGLEPLANPRNATAGTLKTLKSTGPKRWLDCYMYSLLSTDMDLPTHEVCIQWLEKWCFHVSPTYKKCRTLEEVMAYIEYWESAKNSLPVAIDGVVIKVNDTLQQNKLGLTAKSPRWAIAYKYKPENLATILESVDYQVGRTGVITPVAHLKPILLAGTIVKRATLHNAGEIQRLDLHLGDTVFIEKGGEIIPKITGTDVSKRSLDSEPVKFVTHCPACGTELVKRYEKALYYCPNTKGCPYQLQGLLKHFVHRKAMDIRSIGKQTIEMLINRGLVHTPADLYSLKYQDIRSLEGFKDLATRNVLSGIESSKQRPFERVLFALGIRHVGEVIADKITQYYTDIDTLSNATVEDLIAIPFIGTEIAHSVTNYFENPENLALIDVLKQAGLQLSRPQLATVFATQSLPLSGKTFVISGTFQNFEREELKELIKKKGGGILTNISAKLNYLIIGENPGPGKVAQAQALGISTINETEILQMLEL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: COX8A_MOUSE
Sequence: MSVLTPLLLRSLTGSARRLMVPRAQVHSKPAREQLGVLDITIGLTSCFVCCLLPAGWVLSHLESYKKRE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8A, mitochondrial, Cytochrome c oxidase polypeptide VIII-liver, Cytochrome c oxidase subunit 8-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: BFR_BRUME
Sequence: MKGEPKVIERLNDALFLELGAVNQYWLHYRLLNDWGYTRLAKKEREESIEEMHHADKLINRIIFFEGFPNLQTVSPLRIGQNVKEVLEADLKGEYDARASYKESREICDKLGDYVSKQLFDELLADEEGHIDFLETQLDLLAKIGEERYGQLNAAPADEAE
What is the function of this protein?
Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.
What are the official names of this protein?
Bacterioferritin, BFR.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
Protein: RL22_CHLFF
Sequence: MFKATARYIRVQPRKARLAAGLMRNLSVMEAQKQLSFSQLKAGRCLKKVLDSAVANAELNENVKREQLNVIEVRVDAGPVYKRTKSKSRGGRSPILKRTSHLTVIVGERER
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y173_TREPA
Sequence: MYFAILGTMSRTCVRAYAVFAIAIMVLTVAWFAFSISQAIQRNTVGAQQRFAQVIRRIAPRVTSKRQLTDAEADFIQNLCKNDDLIMALNIFSNRVQLFSWTYDDLMFVAGGGSELVPRSSSLFIKIFSGRVPYQAKDECLLFTAALRVLTPANIFFRGCVVFLVMLTLTISSMVFLVIEYLSVRRFQCAQGDARPRPAGPQGTARSRTDEAQVSPGTPPECPVSVF
What are the official names of this protein?
Uncharacterized protein TP_0173.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DGCR6_CHICK
Sequence: MERFGGAGYEVAAAELSRQQERHYRLLSELQELVKALPSSCQQRLSYTTLSDLALALLDGTVFEIVQGLLEIQHLTEKNLYSQRLKLHSEHRGLKQELFHRHKEAQQCCRPHNLPLLRAAQQREMEAVEQRIREEQRMMDEKIVLELDQKVIDQQSTLEKAGVSGFYITTNPQELTLQMNLLELIRKLQQKESESEKAFS
What are the official names of this protein?
Protein DGCR6, DiGeorge syndrome critical region 6 homolog.
What is the protein family that this protein belongs to?
Belongs to the gonadal family.
Protein: SHU2_YEASZ
Sequence: MSKDVIEYSKLFAKLVNTNDDTKLDDTIASFLYYMFPRELFIRAISLLESSDMFIYILDRVHNKEGNEHTSLIDVLVDEFYKGSSNSLLEYRLIVKDTNDGAPPILVDIAHWFCSCEEFCKYFHEALEKTDEKEELHDVLINEVDDHLQFSDDRFAQLDPHSLSKQWYFKFDKICCSHLLAFSILLRSSINVLKFFTVNSNKVFVIAIDNIDEWLNLHINIVE
What is the function of this protein?
Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase.  Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation (By similarity).
What are the official names of this protein?
Suppressor of hydroxyurea sensitivity protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHU2 family.
What are the subcellular locations of this protein?
Nucleus.