PharMolix/UniProtQA huggingface dataset:
Protein: BCHB_RHORT
Sequence: MRLTVWTYEGPPQVGAMRVATAMRGVHYVVHAPQGDSYADLLFTMIERRPGRPAVSYTSFQARDLGTDTAALFKTAAADAVARFQPEALLVGSSCTGELIQDDPGGLAKALGLSIPVIPLELPSYQRKENWGAAETFYRLVRTMAGPAAPAPGTPRAPRPAGQRPRCNLLGPTALGFRHRDDVQAVVALLGRMGVDVAVVAPLGASPADLARLGEADFNVVLYPEIADTAVRWLERAFGQPSVRTVPIGVGATRAFIAEVAAVAGVDPAPALAEESLRLPWWSRSVDSTYLTGKRVFIFGDATHAVAAARVATEEFGFEVVGLGTYAREYARELRACAGALGLEALITDDYLDVEAAIADAHPDLVLGTQMERHIAKRLGVPCAVISAPVHVQDFPARTAPQMGFDGANVLFDTWVHPLMMGLEEHLLMMFRDDFEFHGDAAPSHLSAHRPTGEAVGDAVGEPPAAPRDQAAPAATLDGSAAQSDPARTTPPGAPSWEDSAEKELRKVPFFVRGKARRNTERFAAERGLASISVETLYDAKAHFGR
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: FABR_SALPC
Sequence: MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDIGAEQRRQLEERLVLQLRMIAKGAYYWYRREQEKIAHHSE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LONP2_ORYSI
Sequence: MADAAVELPGRLAILPFRNKVLLPGAIVRIRCTNPSSVKLVEQELWQREEKGLIGVLPVHDSEAAGSLLSPGVGSDSGEGGSKAPGGSAGESTKQDTKNGKETIHWHSRGVAARALHLSRGVEKPSGRVTYIVVLEGLCRFSVQELSARGSYHVARVSRLDMTKTELEHAEQDPDLIALSRQFKATAMELISVLEQKQKTVGRTKVLLETVPVYRLADIFVASFEISFEEQLSMLDSVDLKVRLSKATELVDRHLQSILVAEKITQKVEGQLSKSQKEFLLRQQMRAIKEELGDNDDDEDDVAALERKMQNAGMPANIWKHAQRELRRLRKMQPQQPGYSSSRTYLELLAELPWQKVSEERELDLRAAKESLDRDHYGLTKVKQRIIEYLAVRKLKPDARGPVLCFVGPPGVGKTSLASSIAKALNRKFIRISLGGVKDEADIRGHRRTYIGSMPGRLIDGLKRVSVSNPVMLLDEIDKTGSDVRGDPASALLEVLDPEQNKTFNDHYLNVPFDLSKVIFVATANRMQPIPPPLLDRMEVIELPGYTPEEKLKIAMKHLIPRVLEQHGLSSTYLQIPEAMVRLIIERYTREAGVRNLERNLAALARAAAVKVAEQDSVLRLGKEIQPITTTLLDSRLADGGEVEMEVIPMGQDISNTYENPSPMIVDEAMLEKVLGPPRFDDSEAADRVASPGVSVGLVWTSFGGEVQFVEATAMVGKGDLHLTGQLGDVIKESAQLALTWVRARAADLNLSPTSDINLLESRDIHIHFPAGAVPKDGPSAGVTLVTSLVSLFSHRKVRADTAMTGEMTLRGLVLPVGGVKDKVLAAHRYGIKRVILPERNMKDLAEVPAPILSGLEILLVKRIEEVLDHAFEGGCPLRPHSKL
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix.  Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
What are the official names of this protein?
Lon protease homolog 2, peroxisomal.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: METK_NEIG2
Sequence: MSEYLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAETLVNTGLCVLAGEITTTAQVDYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPDIAQGVNEGEGIDLNQGAGDQGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGRLPWLRPDAKAQLTVVYDSETGKVKRIDTVVLSTQHDPAISHEELSKAVIEQIIKPVLPPELLTDETKYLINPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYACRYVAKNIVAAGLATQCQIQVSYAIGVAEPTSISIDTFGTGKISEEKLIALVCEHFDLRPKGIVQMLDLLRPIYGKSAAYGHFGREEPEFTWERTDKAASLKAAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBK92_ARATH
Sequence: MEYGEEPSIKRFLMLPDDLVFNCLARVSRLHYPTLSLVSKKFRFLLASKELYQTRILLGGTESCLYVCVRLHTDSEQLHWFIIYQGPNSSKKVLVPISSPNFTSAALPGFVVVGHEIYAIGGGSENKNASINATGSKTYNALSSVMVMDSRSHTWREAPSMRVARVFPSACTLDGRIYVTGGCENLNSMNWMEIFDTKTQTWEFLQIPSEEVCKGSEYLSISYQRTVYVGSREKDVTYKMHKGKWRGADICLNHGWSLDPSSCCVIENVFYRCSLGDVRWYDLKKREWAALKGLEGLPTFTNYYRNFKSADHCGKLAISWEEYVLVDDETKIWCAEIAIQKRQNGEIWGTLEWFDNVFISSGPNRHVDLLVNALTATVW
What are the official names of this protein?
F-box/kelch-repeat protein At4g33900.
Protein: PSA_STRGG
Sequence: MSTPFYVSPQQAMADRAEYARKGIARGRSLVVLQYADGIVFVGENPSRALHKFSEIYDRIGFAAAGKYNEYENLRIGGVRYADLRGYTYDRDDVTARGLANVYAQTLGTIFSSAAEKPYEVELVVAEVGSEPEGDQIYRLPHDGSIVDEHGSVAVGGNSEQISTFLDQRHRDGMTLAEALKLAVQALSREPGGGEREIPAERLEVAVLDRTRPQQRKFKRIVGRQLARLLDTEAAGSTPTDAPSDTEDGDSTDGTDRADGTTDSTEETEK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1107L_ASFWA
Sequence: MLVIILGIIGLLASSNLVSSSTSTRVGGHLPLTFDPPENELGYWCTYVESCRFCWDCEDGICTSRVWGNNSTSIVENDYVKYCEVSRWGNLCRYDVEEHIYHSMNCSDPKPWNPYKIARKEWKKNEHPRKDLKKDEF
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-7L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
Protein: ATG1_BOTFB
Sequence: MASTTTSTSSLSSRRQKTGVGSFTINEQIGKGSFATVYRGTHMPSGNLVAIKSVNLSRLNKKLKDNLYVEIEILKSLYHPHIVALIDCRESASHIHLMMEYCELGDLSYFIKKRDRLADNPTLYDMVQKYPMPVEGGLNQVVVRHFFKQLSSAMEFLRERDFVHRDVKPQNLLLIPSPEWIAKRAKGGPEAMKASKESVVAMVGINSLPMLKLADFGFARSLPSTSLAETLCGSPLYMAPEILRYEKYDARADLWSIGTVLYEMMTGRPPFKAINHVQLLQKIEKNQDEIRFPSRGIYSRDLKDIVRRLLKKKPEDRITFPEYFAHPVVTEPIPGLVGDDRPKEKSPETSIVRQPSLRDRQRESPTVKHIDTAYESLITRDIGEQSPRTPNIESNQPFGTPGRSSGRPDSRDRPSPVSAATAPNVDTLPRQRDRKDRTEPNYAPIVRTGSTKQRYDEQANLQPKNEVQSSNSITEAEQDVRDAREYVLVEKKAVEVNAFADEMAANPRLGRANSAPKQLPRRHTSMGEPNSTTGAVAVPPSRIVQRASGRAQPDTSSARNSYGSYGKTGSSPSTASAIAKALQGASVRVFGVSWSPTLIGKGPSPPQLYNPYPAYPTPNAGLIGDGRPIDEDQRVVNIIEDSATRSDVVYGFAEVKYRQLIPLAPSMNHGLGGPNPERTGDAMDEDDGLTVEAIVNLSEEALVLYVKSLSLLSKSMDIAGAWWSRKQRGGIVSGGHTPGSDSSSAAQAGNRINGAVQWVRTRFNEVLEKAELVRLKLVEAQKRLPEDHPGHPNNRSTASRLVGGSSTTDGVVLSSGITAEKLMYDRALEMSRTAAINELANEDLPGCEISYTTAIRMLEAVLENDEELIPRKRSSSLREDKEKSEGGEVNGINFGDRKDVLKVLQMIRTRLQVLKKKMTAIAKHQSMPPPSSSPRRSYSGGTTPTINNTPPK
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes.  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.
What are the official names of this protein?
Serine/threonine-protein kinase atg1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: SALM_DROVI
Sequence: MRSDFKDNHQETINKMIQFGTVKYGIVKQLKDPARSAEKDIASDQEDNGACSPLTTANASASAGNSPCPSRSPQQHSEDEREPEQVSEQELVPEVSAQSESEIGEEIENNADETNADHNHNNNNNNKLVMTKPPVEHEVEQNANLNASMPNSTTPPATNAVIAGARAQQFGATPVTLEAIQNMQMAIAQFAAKTIANGASGTDNEAAMKQLAFLQQTLFNLQQQQLFQLQLIQQLQSQLALNQVKQNDDEADEELEPEEREDGETDTYEEEERIADMELRQKAEARMAESKARQHLINAGVPYANAPDPSHQPPHRCRLRRLKRKREEDASAKSSGASAKIFGEQESSQDALNKLKEMENMPLPFGADLSSSIITNHDDLPEPNSLDLLQKRTQEVLDSASQGILANNMADDFAFGDKSSDGKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHAQKFPHVPMNATPIPEHMDKFHPPLLDQMSPDSSPTQSPAPATGLPPPSTSTLTQMQPSMSFASSPAFPGLPGIYRPPMELLKSLGATAGSTAGLPHPFFPQMPGLGAALKHTHDQSQDMPTDLRKSSGPSSPHEEEDNIAARLPVKSELMEEEKTEHTMEAATRESAEMEPLPLEVRIKEERIDEDQMHLQEGMQKPEPLTAYATPHPQQCLIPTTHAAAKSPRSLPLQCHARLSLWCSHPTTSNHACAVLTGSQTHLDQLPTPDNVPPTMPQREDFFAERFPLNFTSKTDDHSPIRSPAGHAHAHIPRSPFFNPIKHEMAAFVPRPHSNDNSWENFIEVSNTSETMKLKELMKNKKISDPNQCVVCDRVLSCKSALQMHYRTHTGERPFKCRICGRAFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQHIRLHTGEPTDLTPEQIQAAEIRDPPPSMMPGHFMNPFAAAAFHFGAMPGGGAGGPPGATGMPGGPHNGTLGSESSQGDLDDNMDCGDGDDFDDISSEHLSNSNDPAATSDRRSSDDFKSLLFEQKLRIDPTGVVNINSHQRPHSAASNPNSIGSASASPSAPTSPSSQPKPSCSPVRSSCSPVRSVSETSQGALDLTPRALPPPLASSSSRSPYRQLLSVRRRPLARSVSSHRCVVPMVRALLSSQLPPSVGIDCLPPGLQHHLQQQHQHLMQQQXAVAAAAAAQHHHHQMQQHAAALHQHQEHLRREAQEVQQKAAQEVQQKAAAAAAAAAAAQRQESPQPPPRSGESSVGPPAQPNPLISARPPFGMFPNLPIFPPATTQNMCNAMNQIAQSVMPAAPFNPLALSGVRGSTTCGICYKTFPCHSALEIHYRSHTKERPFKCNICDRGFTTKGNLKQHMLTHKIRDMEQETFRNRAVK
What is the function of this protein?
Required for the establishment of the posterior-most head and the anterior-most tail segments of the embryo.  Probably function as a transcriptional regulator.  Could repress the transcription of the tsh gene.
What are the official names of this protein?
Homeotic protein spalt-major.
What is the protein family that this protein belongs to?
Belongs to the sal C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAA_SHESH
Sequence: MAVSLWQQCIGRLQDELSAQQFSMWIRPLQAQMDGDTLVLYAPNRFVLDWVRDKYINIINQFFTEQMGSDAPKLRFDIGSRPSAPRPVQATAAVERPKFEQNTKPAKTSFNVNSPEPAMAANHRSNINRTYQFENFVEGKSNQLGKAAAMQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDKYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQVAMALSKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDTKEDYANLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_OCEIH
Sequence: MIEIEKPKIETVEISENATFGKFVVEPLERGYGATLGNSLRRILLSSLPGAAVTTVQIDGALHEFSTVDGVVEDVTTIILNLKKLALKIYSEEPKTLEIDVQGEGAVTAADLTYDSDVEVMNPDLHIATLNSKGNLHMKLIAERGRGYRPAEENKNDDQPIGVIPIDSIFTPVSRVTYQVENTRVGQVANYDKLTMDVSTDGSIRPEEAVSLGAKIITEHLNIFVGLTDEAQNAEIMVEKEEDQKEKVMEMTIEELDLSVRSYNCLKRAGINTVQELANKSEEDMMKVRNLGRKSLEEVKVKLEDLGLGLRDDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RS4E_METM6
Sequence: MAIKGPRKHLKRLAAPANWQLPRKVKAFTVRPSPGPHSMDKSLPLLLVVRDILKYADNAREAKKIIQTGKILIDGLKRKEYKHPAGLMDVLSIPEMDENYLVLFDESGRISLKKTDKTDAKLCKIVNKTVIKGGHIQLNLHDGRNQIVKVSDATKAEEDVYKTGDSVLVSIPEQSIVGHVAFGEGKLAYITGGKHVGEFAKIVEVENRALYSDIVTLENKDGEKFKTVKPYVFIVGQDEPVISM
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: XNI_SHEHH
Sequence: MNKFLIIDGMNLVRRIHAAQPNESDITGLKERVNGACRKLLKFHQPSHAAIVWDGDAISWRKALFEDYKKGRKPMPEALANGLVELKAYLAEHQLNSINADSEADDVIATLATKLTSINGEAIIVSTDKGFCQLSHPNIKRWDHFNQGYLTIEEMEKKLGVESTQFIDYLALAGDSGNKIPGVPGIGPKSAVELLKIFRSLANIYNSIDKVGSKQAKKLEEGKQMARLSYKLVQLQTDLPLNVNLKQFRIEQ
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: ECDJ_ASPRU
Sequence: MHFAESVQTPPPSRPSDQSLNQHVLDLGSWDQGCRDLMLVNWLCVDFRQRLLNVLYTSCQKNFNEARSLARERLLDLVQRIASSDNLHGALYTPPSLDSRSSATPPQNLPPTPDLVQCIRGCDEPFPPLSLPTPAQIDTQENERLMCTPEDITYHDRDSQVVAQARRRSPPGTGPAVLPPIAFDNHELPPGCSDFLNFDLLSDGEVFSIGTHAGVTSDVCDSMPLDHDLSEMELDPPPDATTTTTTTTVSSPNVHSTHHLAIPNPEPGTPTPPSPLAGTSLTRKPPGTPDSPSAASQRRQRQRRAAAHATYRSTPSPCQSADTHIGAENEVAEPAPPSPSTRWTHSIPTHLPSPDTVLATFTHHLGRGKQSIALLLTRLFYAIGSPDALSQLRDAVKLSREQTPAIIPVSSTNDLATTVKALDHLDSMTTLSHILRRYYLVRLLEHRTRFEQDHVTAKQAWRPPKRMLKYDCARVELIKNGGNCSSSSCSSSASKKNEEKREPPLKYRSKSQALADLMQMLYPDLKPAVAEGKDCVYSRKLTKLRNRLSCARNWYRFEQAFPGAILALIPCAGRFSVSIDQIEKLPSDTVQIFLDYLQEHRGVFSRCVSQTLGTGIFSVLARTSADAAPTFAFEKVEEEGFGDLLYDTDELVSLSIEYDRYCDLNSNA
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of echinocandin B, a fungal lipidated cyclic hexapeptide that acts as an antifungal agent (PubMed:22998630).  Linoleoyl-AMP, produced by the fatty-acyl-AMP ligase ecdI, is transferred to the initiation carrier domain (T0) of ecdA (PubMed:22998630).  The linoleoyl-S-phosphopantetheinyl-T0 is sequentially extended with L-ornithine, L-threonine, L-proline, L-homotyrosine, L-threonine, and 4R-methyl-L-proline to form the linear hexapeptide (PubMed:22998630).  Thereafter, the terminal condensation (C7) performs macrocyclization of the NRPS product and the cyclic scaffold is released from ecdA (PubMed:22998630).  All six of the amino acid residues are hydroxylated, including 4R,5R-dihydroxy-L-ornithine, 4R-hydroxyl-L-proline, 3S,4S-dihydroxy-L-homotyrosine, and 3S-hydroxyl-4S-methyl-L-prolin (PubMed:22998630).  In the pathway, all the hydroxylation reactions are proposed to occur following completion of the cyclic peptide, so the unhydroxylated precursor produced by ecdA will undergo six rounds of hydroxylation (PubMed:22998630).  Five hydroxylase genes (ecdG, ecdH, ecdK, htyE and htyF) are embedded within the echinocandin B (ecd) and L-homotyrosine (hty) clusters (PubMed:22998630).
What are the official names of this protein?
Echinocandin B biosynthetic cluster protein J.
Protein: HSLO_SHIBS
Sequence: MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSREHCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_HYDCU
Sequence: MSNPPSKLYIGLMSGTSLDGVDAALVSIQNGELELKAFQTFPYTDNLKKQLHHLNQTPHVDLKALCDMEYQVANAFSEATQQLLDNCDHVASDIRAIGSHGQTIFHAPDIPMSLQIGHPAFIAKNTGITTVADFRIDDMANNGQGAPLAPAFHQKLFGNTVGTAVVNIGGISNITFLDQQKTLGFDTGPGNGLMDEYCEQFFNCSYDADGKMAQTGQVNMALLSDLMQEPYFRLPAPKTTGKDLFNSDWLNPFLAKYSNVSKKDILSTLNQLTVDTIIQGLNTLPSQPKRLLICGGGAENKTLISRLQAQLSYPVKTTQSVGVPPHAIEAMMCAWLAEQRLNNTPIALQHITGATKDSVLGAVWHP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: NDK_NITWN
Sequence: MAIERTFSILKPDATARNLTGAINALIEKAGLRIVAQKRIRMTREQAETFYAVHKARPFFGELVDFMISGPVVVQVLEGEGAILKYRDIMGATDPSKAADGTIRKLHAKSVGENSVHGSDATETAAVEIAQFFSGNEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_LATSS
Sequence: MPNFNRHQIRQAAFQVLFTLNANQSLELEDAYQAVLTMDQFDAEEVTPVEVPAYLAFLVSGVTENQAALDAALTPYLKKGWQLSRLAKPDLIILRLGLFEMQNSTEAPAKVALNEALELAKQFTDDQAKGFINGVLSKFVEA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RNPH_PSEAE
Sequence: MNRPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGVPRFLKGQGQGWLTAEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLRAALDLSKLGENTLYIDCDVIQADGGTRTASITGATVALIDALAVLKKRGALKGNPLKQMVAAVSVGIYQGVPVLDLDYLEDSAAETDLNVVMTDAGGFIEVQGTAEGAPFRPAELNAMLELAQQGMQELFELQRAALAE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RL2_STAAS
Sequence: MAIKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSIQYDPNRSANIALVVYADGEKRYIIAPKGLEVGQIVESGAEADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGASAQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HACA_METTH
Sequence: MVKMNMTEKILAEAAGLREVTPGEIIEARVDLAMTHDGTSPPTIRTFRDIASRGGPARVWDPERIVMVFDHNVPANTIGAAEFQRVTREFAREQGIVNIFQNAAGICHQVLPERGFVRPGMVIVGADSHTCTYGAFGAFATGMGATDMAMVFATGKTWFMVPEAMRIEVTGEPEGHVYAKDVILHIIGEIGVDGATYRSVEFTGDTIESMDVSGRMTICNMAVEMGAKNGIMEPNRQTLDYVRARTGREFRVYSSDEDSQYLEDHHFDVSDLEPQVACPDDVDNVYPVHRVEGTHIDEAFLGSCTNGRYEDLKIAAEVIGDRRVHEDVRFIVSPASREIYLKALEDGIIETFIRAGAIVCNPGCGPCLGAHMGVLAPGEVSIATTNRNFRGRMGDPASSVYLANPAVVAESAIEGVISAPQQEAGNGC
What is the function of this protein?
Component of a hydro-lyase with broad substrate specificity for cis-unsaturated tricarboxylic acids.  Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4-tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4-tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate).  Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)-aconitate.  These reactions are part of the biosynthesis pathway of coenzyme B.
What are the official names of this protein?
Probable methanogen homoaconitase large subunit, HACN, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: AATM_BOVIN
Sequence: MALLHSGRFLSGVAAAFHPGLAAAASARASSWWAHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIAGLAEFCKASAELALGENNEVLKSGRYVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQSYRYYDPKTCGFDFTGAIEDISKIPAQSVILLHACAHNPTGVDPRPEQWKEMATVVKKNNLFAFFDMAYQGFASGDGNKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPMYSNPPINGARIASTILTSPDLRKQWLHEVKGMADRIISMRTQLVSNLKKEGSSHNWQHIIDQIGMFCYTGLKPEQVERLTKEFSIYMTKDGRISVAGVTSGNVAYLAHAIHQVTK
What is the function of this protein?
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA).  As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance.  Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism.  Facilitates cellular uptake of long-chain free fatty acids.
What are the official names of this protein?
Aspartate aminotransferase, mitochondrial, mAspAT, Fatty acid-binding protein, FABP-1, Glutamate oxaloacetate transaminase 2, Kynurenine aminotransferase 4, Kynurenine aminotransferase IV, Kynurenine--oxoglutarate transaminase 4, Kynurenine--oxoglutarate transaminase IV, Plasma membrane-associated fatty acid-binding protein, FABPpm, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Cell membrane.
Protein: LY66F_RAT
Sequence: MAMVVFLLLYLCGHPQAAADNIQTLYVPSGESMEMPCPSPPSLLGGQLLTWFRSPVSGSSTILVAQVQVDRPISDLGKADPDSRFKVLGNYSLRLEGSRDEDAGRYWCTVMDQNHKYQNWRVYDVSVLKGSQFSVKSPDGLSCSALLCSVVPARRLDSVTWLEGRNPVRGHAQYFWGEGAALLLVCPTEGVPETRSRRPRNIRCLMPQNKRFSFSVAAPAEPPPTVCAPLPSWDVSWILMLLFAAGQGVTIIALSIVIWRHQRAQGTQDREPSIPHFKPEVQVYENIHLARLR
What is the function of this protein?
May play a role in the downstream signal transduction pathways involving GRB2 and GRB7.
What are the official names of this protein?
Lymphocyte antigen 6 complex locus protein G6f.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.