Protein: POLG_AEVL2
Sequence: MSKLFSTVGRTVDEVLSVLNDEDTESYAGPDRTAVVGGGFLTTVDQSSVSTATMGSLQDVQYRTAVDIPGSRVTQGERFFLIDQREWNSTQSEWQLLGKIDIVKELLDQSYAVDGLLKYHSYARFGLDVIVQINPTSFQAGGLIAALVPYDQVDIESIVAMTTYCHGKVNCNINYVVRMKVPYIYSRGCYNLRNSAYSIWMLVIRVWSRLQLGSGTSTQITITTLARFVDLELHGLSPLVAQMMRNEFRLSSSSNIVNLANYDDARAKVSLALGQEEFSRDSSSTGGELVHHFSQWTSIPCLAFTFTFPGTVGPGTHIWSTTVDPFSCNLRASSTVHPTNLSSIAGMFCFWRGDIVFEFQVFCTKYHSGRLMFVYVPGDENTKISTLTAKQASTGLTAVFDINGVNSTLVFRCPFISDTPYRVNPTTHKSLWPYATGKLVCYVYNILNAPASVSPSVSINVYKSAADLELYAPVYGVSPTNTSIFAQGKEDEGGFFSVPEVEQHVVEDKEPQGPLHVTPFGAVKAMEDPQLARKTPGTFPELAPGKPRHTVDHMDLYKFMGRAHYLWGHEFTKTDMQYTFQIPLSPIKEGFVTGTLRWFLSLFQLYRGSLDITMTFAGKTNVDGIVYFVPEGVAIETEREEQTPLLTLNYKTSVGAIRFNTGQTTNVQFRIPFYTPLEHIATHSKNAMDSVLGAITTQITNYSAQDEYLQVTYYISFNEDSQFSVPRAVPVVSSFTDTSSKTVMNTYWLDDDELVEESSHSSFDEIEEAQCSKCKMDLGDIVICSGEKAKHFGVYVGDGVVHVDPEGNATNWFMKRKATVKKSKNLDKWCFALSPRIDRTLICETANLMVGREVEYDIFVKNCETYARGIASGDYGTKEGEKWKTLLSAVGVAAMTTTMMAMRHQLLDTSLTKLPQKVGEVTNEVRKILEDTSAGVREFKEKVSSILRKTWPGKTSIKIMKWTFRIVKMCVGVGLCYAHGWDSKPVTAVVTMFSMDFLDLVIDGIEIGRMIIHELTTPKAQGLSEINQVLSIAKNAKDVIKMLIEIFCKVIERITGEHGKKIQWAQDKKEEIMNVLERAEKWITTSDDHSEGIECLKLVRSIQSVIRGEESLKELAGELRAVGTHVLNKLGRLDKPNAPILVRAEPTVLYLYGNRGGGKSLASMAIAVKLCKELGISHVEGIYTKPIMSDFWDGYAGQPVVIMDDLGQSTSDEDWTNFCQLVSSCPLRLNMANLEKKGTQFNSPFIIASSNLSHPCPKTVYCTDAIARRLHIKVKVSPKEEFSTHAMLDVAKAKKAGAYCNLDCLDFQKISDLASTPVSVQDIVLALLHTNVDKQTVMGNIIQYWAQSNPREVFDTMAEGKNSGKYLWLFEKIKTSKWYILGCVGAALSVSVLGVFAYHMIKNHFRDQQHDQSAYSAAIKPLRVVRLEQSDAQSVVDISNVVHGNLVRVGVGPNEARIHWLNNGWGVYNTYILMPYHGIKDADVDDDLYIERAGTIYSTNMKMVQVLFLESREGDLVLINVPRLPKFRDIRNHFSTEENIRRAEGMPGTLCTLDHERFTLVTESDLKMVEAATYVCEDDKGVRTDISVGRSWKAKACTVAGMCGGALVTSNNKMQNAIVGIHVAGGAPAISRVITKEMIEEMLKTRAQCSRIWKTEFVEKKISVGSKTKYHKSPLYDFCPQKVIKCPTKLFYQGEIDVMQVMLAKYSSPIVSEPLGYATVVEAYTNRMVSFFSEPRQLTYDECINGIEGLDAIDLKTSAGFPYNTLSLKKSDLIINGKKAQRLQQDVEKMEEDLHMNRSIQVVFTTCAKDELRPLSKGMLGKTRAIKACPVSFTILFRKYLGYALAQIQSHPGFHTGIAVGVDPDQDWHCMWYSIVTQCDLVVGLDFSNYDASLSPFMIYHAGRVLGQICGLDPRLVDRIMEPIVNSVHQLGSMRYYVDGSMPSGTPATSVLNSIINVVNISHVLCALEKISVFEVFKLSKILTYGDDVLFCIKKESLDQKSFPLSSFVQGLKELGMSPTGADKMEVKVTPVHKMSFLKRTFYVDEWSICHPRISEETVYSMLAWKSDNASMKHVIETSIWFMFHHGPRKYVIFCTCLRGVLCRVGIGLYIPTYKELEVRYDRLVKDRVIDDSF
What is the function of this protein?
RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals.
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the picornaviridae polyprotein family.
What are the subcellular locations of this protein?
[Capsid protein VP2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein VP3]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein VP1]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Protein 2B]: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Probably localizes to the surface of intracellular membrane vesicles that are induced after virus infection as the site for viral RNA replication. These vesicles are derived from the endoplasmic reticulum (By similarity). SUBCELLULAR LOCATION: [Protein 2C]: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Probably localizes to the surface of intracellular membrane vesicles that are induced after virus infection as the site for viral RNA replication. These vesicles are derived from the endoplasmic reticulum. May associate with membranes through a N- terminal amphipathic helix (By similarity). SUBCELLULAR LOCATION: [Protein 3A]: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Probably localizes to the surface of intracellular membrane vesicles that are induced after virus infection as the site for viral RNA replication. These vesicles are derived from the endoplasmic reticulum (By similarity). SUBCELLULAR LOCATION: [Protein 3B]: Virion. SUBCELLULAR LOCATION: [Protease 3C]: Host cytoplasm. SUBCELLULAR LOCATION: [RNA-directed RNA polymerase 3D-POL]: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Interacts with membranes in a complex with viral protein 3AB. Probably localizes to the surface of intracellular membrane vesicles that are induced after virus infection as the site for viral RNA replication. These vesicles are derived from the endoplasmic reticulum (By similarity).