PharMolix/UniProtQA huggingface dataset:
Protein: SYH_SHESW
Sequence: MAKQIQAIRGMNDILPTQSPLWQKVEAVLRSSVSAYGYSEIRTPIVENTDLFKRSIGEVTDIVEKEMYTFEDRNGDSLTLRPEGTASTVRAGNEHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQFGVEVYGIGSADIDAEVLMLSARLWEKLGISEHVTLELNTLGDPAERAAYRDALIAFLEQHKDKLDEDSQRRMYSNPLRVLDSKDPQVQGILTDAPALMDYLGEESSQHFAQLRELLDAVGIQYRVNPRLVRGLDYYNRTVFEWVTNSLGSQGTVLAGGRYDGLVAQLGGKDTPAVGFAMGLERIVLLLETLGLTQDIPAAVDVYVTAMGENCLVEAIKVAQELRSALPHLKVMSHCGGGNVKKQMKRADKSGASVALLIGEEELAEGMVTVKHLRNDNEQQQVARNALSAFLAELTK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIT_ECOL6
Sequence: MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSVLVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine.
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HNMT_PONAB
Sequence: MVSSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIARIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKGPVAKTSNLENVKFAWHKETSSEYQSRILEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQNDLCQYVTSDDLTQMLDNLGLKYECYDLFSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLKAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
What is the function of this protein?
Inactivates histamine by N-methylation.  Plays an important role in degrading histamine and in regulating the airway response to histamine.
What are the official names of this protein?
Histamine N-methyltransferase, HMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZO8I_XENLA
Sequence: HKREADFCSKGNLTNPEISPVEHYPPTNEIKEEATSWEEGNQSDYSINSLTEQIQGPYTPTPIMEYNHLIMQDNKYDVNACNSPLQETDVTKHALHKRDIDRRQRTQTQLKYDHRTNTGDKPLSCSECGKCFSTYHVLARHQKTH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Oocyte zinc finger protein XlCOF8.4I.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRE2_STAAU
Sequence: MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENYDLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRFFEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQDKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYSDKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTAARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEENKSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHDLEPKKNEFELTHNREVKKERSRDQGMSL
What is the function of this protein?
The interaction of the RSA site and the PRE protein may not only serves a function in plasmid maintenance, but may also contributes to the distribution of small antibiotic resistance plasmids among Gram-positive bacteria.
What are the official names of this protein?
Plasmid recombination enzyme type 2, Mobilization protein, Plasmid recombinase.
What is the protein family that this protein belongs to?
Belongs to the plasmid mobilization pre family.
Protein: SEC23_USTMA
Sequence: MNVDDVEDRDGVRLSWNVWPSSKIEATRTVVPISALYTPLKEREDLPPVLYEPVTCKPPCRAVLNPYCQIDVRGKLWICPFCLSRNAFPPHYKDISSTNLPAELLPKYTTIEYTLSRPAQIPPIFLYVVDTCMDDDDLKALREALVVSLSLLPPNALVGLITYGTMAQVHELGYDACPKSYVFRGTKEYAPKAIQDMLGLNPGARPMGAGAPGAPGGPSQAPRPPNATAQMGASRFLLPVSQCEFQLTQILEQLQKDPWPVANDKRSQRCTGVALSVAVGMLETTFPNTGARVMLFCGGPATEGPGMVVSTELRERIRSHHDIDKDNAKYYKRAIKFYEAMAKRAAGNGHTIDVFAGCLDQVGLLEMKGLANLTNGHMILADSFQMGIFKQSFHRLFQKDDQGHLQMGFNATLDVQCTKELKVSGLIGHAVSANKKSGCVGETEIGIGQTSAWKLCSLTPRTSAGIYFEVVTPAGQPMQPGSRGLIQFVTHYQHASGQYRLRVTTIARNFAEGGSGQIAASFDQEAAAVLMARIAVFKAEIDDSPDVLRWLDRMLIRLCQKFADYRKDDPTSFRLGENFSIYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNTEDVNNSLIMIQPTLMSYGFEGPPQPVLLDSVSIRPDVVLLLDTFFHILIFHGETVAQWRKAGYQDQEGYENFKEVLENPRADAQDLLADRFPIPRYIVCDQNGSQARFLLSKLNPSTTHMSGGMYGSSGNSGAAIFTDDVSLQVFMEHLKRLAVGASSN
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC23.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y724_STAAB
Sequence: MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKIALEDLISK
What are the official names of this protein?
Epimerase family protein SAB0724c.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
Protein: SIAH2_HUMAN
Sequence: MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:9334332, PubMed:11483518, PubMed:19224863).  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (PubMed:9334332, PubMed:11483518, PubMed:19224863).  Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes (PubMed:9334332, PubMed:11483518, PubMed:19224863).  Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (GPS2, POU2AF1, PML, NCOR1), a cell surface receptor (DCC), an antiapoptotic protein (BAG1), and a protein involved in synaptic vesicle function in neurons (SYP) (PubMed:9334332, PubMed:11483518, PubMed:19224863).  Mediates ubiquitination and proteasomal degradation of DYRK2 in response to hypoxia (PubMed:22878263).  It is thereby involved in apoptosis, tumor suppression, cell cycle, transcription and signaling processes (PubMed:9334332, PubMed:11483518, PubMed:19224863, PubMed:22878263).  Has some overlapping function with SIAH1 (PubMed:9334332, PubMed:11483518, PubMed:19224863).  Triggers the ubiquitin-mediated degradation of TRAF2, whereas SIAH1 does not (PubMed:12411493).  Promotes monoubiquitination of SNCA (PubMed:19224863).  Regulates cellular clock function via ubiquitination of the circadian transcriptional repressors NR1D1 and NR1D2 leading to their proteasomal degradation (PubMed:26392558).  Plays an important role in mediating the rhythmic degradation/clearance of NR1D1 and NR1D2 contributing to their circadian profile of protein abundance (PubMed:26392558).  Mediates ubiquitination and degradation of EGLN2 and EGLN3 in response to the unfolded protein response (UPR), leading to their degradation and subsequent stabilization of ATF4 (By similarity).  Also part of the Wnt signaling pathway in which it mediates the Wnt-induced ubiquitin-mediated proteasomal degradation of AXIN1.
What are the official names of this protein?
E3 ubiquitin-protein ligase SIAH2, RING-type E3 ubiquitin transferase SIAH2, Seven in absentia homolog 2, Siah-2, hSiah2.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Partially nuclear.
Protein: SYGA_SHIF8
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_MYCSK
Sequence: MTIEPRATADLVDDIGPDVRSCDLQLRQFGRRPEFAGRVTTVRCFQDNALLKSVLSEPGDGGVLVIDGDGSLHTALVGDVIAALGRDNGWSGLIINGAVRDASTLRTLDIGIKALGTNPRKSTKTGAGERDVPVDFGGVTFTPGDVAYSDDDGIVVVTP
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: ATPE_BUCBP
Sequence: MNNNKVYSLNVVSFEKIIFNDFVKKIQVSGSEGELGIYPGHLQLLSLIKPGPLLILDDHDYQHVIYISGGIIEVQPTVVSILADTAIRGLDLDLNVVLDKKLKLENKISNVDCIDRNDVIQQLSCELAKLRVIEMFKNQYIKKNN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SECA1_MYCSK
Sequence: MLDKLLRLGEGRMVKRLKKVADYVNTLSDDVEKLSDAELRAKTDEFRKRIDGGEDLDDLLPEAFAVAREAAWRVLSQRHFDVQVMGGAALHFGNVAEMKTGEGKTLTCVLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGRVHRFLGLDVGVILSGLTPDERRAAYHADITYGTNNEFGFDYLRDNMAHRLEDRVQRGHNFAVVDEVDSILIDEARTPLIISGPADAASNWYSEFARLAPLMEKDVHYEVDLRKRTVGVHEVGVEFVEDQLGIENLYEAANSPLVSYLNNALKAKELFQRDKDYIVRNGEVLIVDEFTGRVLLGRRYNEGMHQAIEAKEHVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELHEIYKLGVVPIPTNRDMIRQDQTDLIYKTEEAKFIAVVDDVYERYEKGQPVLIGTTSVERSEYLSKQFTKRKIPHNVLNAKYHEQEANIIAEAGRLGAITVATNMAGRGTDIVLGGNVDFLADKRLREQGLDPVETPEEYEAAWESTLNQIKAEAEEEADDVRAVGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDELMRRFNGATLEALLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRKNVLKYDEVMNQQRKVIYEERRRILEGEDLAEQAHKMLVDVVTAYVNGATAEGYAEDWDLEQLWTALKQLYPVGIDYHDLVDSDAVGEAGELTREELLDMLIKDAERAYAERERELEELAGEGAMRQLERNVLLNVIDRKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQREGYDMFVGMLEALKEESVGFLFNVTVEAAPAAPSNRVAPVAAPPGLSEFAAAAAKAQEQTGQGAVATKERETPAPTLRAKGIDNDDTPPLTYVGPGEDGSAEVQRSNGGPRHAAPGGATRRERREAARKQAKTSKPTRRRG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: DDL_HELP2
Sequence: MEFCVLFGGASFEHEISIVSAIALKEVLKDRIKHFIFLDENHHFYLIEASNMHSKYFAQIKEKKLPPLILAHNGLLKNSFLGTKIIELPLVINLVHGGDGEDGKLASLLEFYRIAFIGPRIEASVLSYNKYLTKLYAKDLGVKTLDYVLLNEKNRANALDLIKFNFPFIVKPSNAGSSLGVNVVKEEKELVYALDSAFEYSKEVLIEPFIQGVKEYNLAGCKIKTDFCFSYIEEPNKQEFLDFKQKYLDFSRNKAPKANLSNALEEQLKENFKKLYNDLFSGAIIRCDFFVIENEVYLNEINPIPGSLAHYLFDDFKTTLENLAQSLPKTPKIQVKNSYLLQIQKNK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GON3_HAPBU
Sequence: MEAGSRVIMQVLLLALVVQVTLSQHWSYGWLPGGKRSVGELEATIRMMGTGGVVSLPDEANAQIQERLRPYNIINDDSSHFDRKKRFPNN
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Progonadoliberin-3, Progonadoliberin III.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y171_GEOSL
Sequence: MKIWIDADACPRAVKEILFRASTRLRVPLCLVANRSLAKHAGPLVESVVVADGFDVADDYIAEHAAPTDLVVTADVPLAARIVAKGGVALDPRGELYSEESIGERLAMRDLLSELRDTGMIQGGGPAPFSMSDRNRFASALDSLLHRMLRR
What are the official names of this protein?
UPF0178 protein GSU0171.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: VIRG_AGRT9
Sequence: MIVHPSRENFSSAVNKGSDFRLKGEPLKHVLLVDDDVAMRHLIIEYLTIHAFKVTAVADSTQFTRVLSSATVDVVVVDLNLGREDGLEIVRNLAAKSDIPIIIISGDRLEETDKVVALELGASDFIAKPFSIREFLARIRVALRVRPNVVRSKDRRSFCFTDWTLNLRQRRLMSEAGGEVKLTAGEFNLLLAFLEKPRDVLSREQLLIASRVRDEEVYDRSIDVLILRLRRKLEADPSSPQLIKTARGAGYFFDADVQVSHGGTMAA
What is the function of this protein?
VirG is required for the positive regulation of at least two vir loci encoded by the Ti plasmid of A. tumefaciens.
What are the official names of this protein?
Regulatory protein VirG.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_MAGMM
Sequence: MGVTVDLEVVTPEKLILSETVQLVTVPGSEGYFGVLSGHVPMISSLRSGVVRMGQGDDAVHLAVSKGFAEVRPDRVTLLVDRAVFGKKVDAAAVTKIRDAAQDELDGTPTESEEYETLRDKLDFANAQLAALEGELV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TIM23_XENTR
Sequence: MDTNHPGSAGGRGGLGSIFGGGSPGYSHSDLAGVPLTGMSPLSPYLNVDPRYLVQDNDEFILPTGANKTRGRFELAFFTIGGCCMSGAAFGAVNGLRLGFKETQNMAWSKPKNVQILNMVTRQGALWANTLGSLALLYSAFGVIIEKTRGAEDDLNTIAAGTMTGMLYKSTGGLRGVARGGLAGLALTSAFALYNNWEHIKGSSSRLSL
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim23.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UREG_AGRFC
Sequence: MKSGNGPLRVGIGGPVGSGKTALTEKLCKAMSGDYSVAVVTNDIYTKEDAEALVRMQALPSERIVGVETGGCPHTAIREDATINLQAIAGLNAQFPDLDVVFIESGGDNLAATFSPDLADITIYVISVCQGEEIPRKGGPGITRSDLLVINKKDLAPYVGADLTVMDSDATRMRNAMPFVFTDMKRGDGVDRIVGFLKEQGGL
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLH2_HUMAN
Sequence: MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMAPIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVALVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGAMQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGNQPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISADTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGAEKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGILLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYLRANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDEEPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAILGNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSVEDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVNFSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDRFGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQFSTDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYYDSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVLEETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEVVQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQVGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFACMDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTELAILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMSHPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFSKAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDNFDNISLAQQLEKHQLMEFRCIAAYLYKGNNWWAQSVELCKKDHLYKDAMQHAAESRDAELAQKLLQWFLEEGKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSKVDKLDALESLRKQEEHVTEPAPLVFDFDGHE
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.  Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network (By similarity).
What are the official names of this protein?
Clathrin heavy chain 2, Clathrin heavy chain on chromosome 22, CLH-22.
What is the protein family that this protein belongs to?
Belongs to the clathrin heavy chain family.
Protein: SYE_NEIG1
Sequence: MTVKTRFAPSPTGYLHIGGVRTALFSWAFARHHKGEFLLRIEDTDLARSTAESVNIILDGMKWVGLDYDNADNVVYQTRRFDRYKEVIAELLAKGDAYYCYCSKEELEAMREKAEKEGTATYDRRWRPEAGKTLPEIPAGVQPVVRFKTPLDGVTKWTDLVKGEISIPNEALDDLIIARADGTPTYNFCAVVDDYDMGVTHIIRGDDHVNNTPKQINILKAIGANLPEYGHLPMILNEQGKKISKRSGDTVAITDFGAMGILPEAMLNYLARLGWAHGDDEFFTTEQFIEWFDLKDVSPSPSRMDLKKLYWINGEHIKITPDGKLTELVKPRLALRDIHETEKPALEDVLALVKDRAQDLNALADECLYFYKKQVPAEADVAKHWDDEAAARMLRFAERLEGLEDWNAKAIHDLFKPFCDEEGIKMGKLGMPLRLAVCGTAKTPSVDAVLALISKEKVLKRIRA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2861_DESPS
Sequence: MVTEWKNFFKGCCMQLLNVGFGNTVMVGRVVAVVNTGSSPARKIREIAKKNGKLIDVTEGRRTRSMLVMDSNHVVLSSVQSDTISQRLQAMRIDLQLGECREQGKKVYNENE
What are the official names of this protein?
Putative regulatory protein DP2861.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: GATA_EMENI
Sequence: MSLLLEAERYVANQSSNRMLNAFITPLCRHSGRWHDQAKDADIRGKQGKLRSRLDGRFIAFKDNICTRDFPTTCASKSLDTFTSPFNATVVQQLEDAGAIVAGKTNLDEFGMGSHSIYSSFGHVMNTRRGDDSKFLSAGGSSGGNAVAVATDQCYAALGTDTGGSIRLPAAYTGTVGFKPSYGLLSRWGVIAYANSLDTVGILAKRVSVARDVFDVLNKHDPRDPTSISPSSRSRISSKLNLPQLTSRLTSRPLRIGIPLEYNISELAPSVRQAWCHSLEYLRQQGHTIQPVSLPMTKLALSAYYVLAPAEASSNLAKYDGVRYGTRSDDSTENQSETYLYAKTRGAGFGPEVKRRIMLGAFSLSAQAIDNYFIQAQRIRRLVRHDFDAAFQAEHPLAAEIRNVELRQQAKQTGIDVLISPTAPTPPPTISDITDTSTKRSNLDAYINDVFTVPASLAGLPAISVPVSGKDNAGNQEGDILAGIQVIGQYGDDELVLKVGELLERR
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACPS_BACC0
Sequence: MIVGIGIDIIELNRIEKMLDGKLKFMERILTENERNVAKGLKGSRLTEFVAGRFAAKEAYSKAVGTGIGKEVSFLDIEVRNDDRGKPILITSTEHIVHLSISHSKEFAVAQVVLESSSS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBNL3_HUMAN
Sequence: MTAVNVALIRDTKWLTLEVCREFQRGTCSRADADCKFAHPPRVCHVENGRVVACFDSLKGRCTRENCKYLHPPPHLKTQLEINGRNNLIQQKTAAAMFAQQMQLMLQNAQMSSLGSFPMTPSIPANPPMAFNPYIPHPGMGLVPAELVPNTPVLIPGNPPLAMPGAVGPKLMRSDKLEVCREFQRGNCTRGENDCRYAHPTDASMIEASDNTVTICMDYIKGRCSREKCKYFHPPAHLQARLKAAHHQMNHSAASAMALQPGTLQLIPKRSALEKPNGATPVFNPTVFHCQQALTNLQLPQPAFIPAGPILCMAPASNIVPMMHGATPTTVSAATTPATSVPFAAPTTGNQLKF
What is the function of this protein?
Mediates pre-mRNA alternative splicing regulation.  Acts either as activator or repressor of splicing on specific pre-mRNA targets.  Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle.  Antagonizes the alternative splicing activity pattern of CELF proteins.  May play a role in myotonic dystrophy pathophysiology (DM).  Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.
What are the official names of this protein?
Muscleblind-like protein 3, Cys3His CCG1-required protein, Muscleblind-like X-linked protein, Protein HCHCR.
What is the protein family that this protein belongs to?
Belongs to the muscleblind family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Greater concentration in the nucleus. In both DM1 and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts.
Protein: GL31_ORYSJ
Sequence: MRAAVAHRILLSLALFAVLCRCDPDLLFDYCVADTAAATAAGAFHLNGLACIDPALARADHFATSALSRATNPAATLYGFNATLTSPAASLPGANAQGLAMARIDLAPGGMAPPHSHPRASEAALVLSGSVLVGFADTSYRLYTQLLRAGEAFVFPRAMVHFLYNMDTAAPAVVLSGLNSQSPGAQLVPFSAFRTEPRLPDEVLKKAFKITGQDVQRIQKHLGGL
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 3-1.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.