PharMolix/UniProtQA huggingface dataset:
Protein: CLA28_ANOGA
Sequence: MKVLLFCIVISLTTLIASGQDIEEELRCPGGYCVSKYLCPNGTFIDDIKHAQTTQLIGLRAGLDIDDFDDCNDYLLVCCQSAPAPTATSTEKPATSDELIEPPPSTNLACGQANEGGLIYDLRNNETLSQYAEYPWVVYILALKKQEANSGDFVCGGTLIHSRLVVTTAHNTDGKTDLVARFGEWDISTTKEPFPQQDIDVAEVIKHPQYVFNPIQNDIALLVLAENVQYAAHIRPICLPQPTDEFVGQRCVSNGWGKERGVYANVMKKLTLPVIGRANCTRMLRYAGLGPFYTLREGFLCAGGEVAVDMCKGDGGSPLACQTESGTYVLAGIVSWGIGCGGFNTPGVYVAVNRYVQWLNEHIVDQALNESFDIKL
What is the function of this protein?
Inactive serine protease which plays an essential role in the innate immune response against bacteria, fungi and protozoa infection by activating the melanization cascade (PubMed:31765430, PubMed:33045027).  In the melanization cascade, acts downstream of TEP1, SPCLIP1 and CLIPA8 to promote CLIPC9 proteolytic cleavage (PubMed:31765430, PubMed:33045027).  In the susceptible strain G3, appears to be dispensable for parasite P. berghei ookinete elimination which occurs by lysis (PubMed:31765430).  Required for the melanization of Gram-positive and Gram-negative bacteria (PubMed:31765430, PubMed:33045027).  Required for the melanization of fungus B. bassiana (PubMed:31765430).
What are the official names of this protein?
Inactive CLIP domain-containing serine protease A28.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the hemolymph.
Protein: RIPS_TRIKI
Sequence: MIRFLVFSLLILTLFLTAPAVEGDVSFRLSGATSSSYGVFISNLRKALPYERKLYDIPLLRSTLPGSQRYALIHLTNYADETISVAIDVTNVYVMGYRAGDTSYFFNEASATEAAKYVFKDAKRKVTLPYSGNYERLQIAAGKIRENIPLGLPALDSAITTLFYYNANSAASALMVLIQSTSEAARYKFIEQQIGKRVDKTFLPSLAIISLENSWSALSKQIQIASTNNGQFETPVVLINAQNQRVTITNVDAGVVTSNIALLLNRNNMAAIDDDVPMAQSFGCGSYAI
What is the function of this protein?
Abortion-inducing protein.  It inactivates eukaryotic 60S ribosomal subunits.
What are the official names of this protein?
Ribosome-inactivating protein karasurin-C, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: MTLD_VIBPA
Sequence: MKNAVHFGAGNIGRGFIGKLLADAEVEVTFADVDVPLVDQLSHKQEYKVKVVGTECKIDTVTHVTAVNSASEDVIDRIVKTDLVTTAVGPNVLDIIAKTIAKGIAKRFEAGNDAPLNIIACENMVRGTTHLKGEVYKHLDKSLHAKADELVGFVDSAVDRIVPPAEAANDDPLEVTVESFSEWIVDEQQFKGDIPNIAGMEKTNNLMAFVERKLFTLNTGHCITAYLGCLKGHRTIREAIEDPNIHAEVKQAMQESGEVLIRRYGFDHDMHNAYIEKILGRFANPYLVDEVDRVGRQPIRKLGANDRLVKPLLGTIEYGTENQTLLKGIAAALKYTNDTDPQAVELQTSLKEVGVTKTLAKYTGLAEDSDEVAQIETLYNQL
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: PSDE_DICDI
Sequence: MNRSLMSLLGREGLGEKITDATPLPDTAETIHISSLALLKMLQHARAGVPLEVMGLMLGELIDEYTIRVIDVFAMPQSGTSVSVEAIDPVFQTKMLDMLKQTGRDEIVIGWYHSHPGFGCWLSSVDVNTQQSFEQLQSRAVAVVVDPLQSVRGKVVIDAFRTIKTSPTAEPRQITSNLGHLQDPSIQALIHGLNRNYYSIAINYRKNELEQKMLLNLHKKKWTEGLIVDKFDTHEQSNEKQINNLLELTKQYQKSIQDEDKIEPEKKEVSAVGKLDPKRHLISDVHTLMANNVVRVLTVMLDTVTF
What is the function of this protein?
Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains.  The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity).
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 14, 26S proteasome regulatory subunit RPN11, Sks1 multidrug resistance protein homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. PSMD14 subfamily.
Protein: RNH2_ECO57
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPPA_HALH5
Sequence: MMSRKRWLALIAAAMLFVASAAISLVSSPAVDVDEWVGTGTSYKQTIVETGTDFGKSIAILELSGVIQDTGSAPSLLNTGVYHHRDFLKQLEKAGEDPNIAGIILQVNTPGGGVLESAEIHKQVEEIVQDSEKPVYVSMGNMAASGGYYISAPATKIYAHPQTITGSIGVIMQSIDISGLAENLGIEFNTFKSGPYKDILSQTREVTDEEEDILQTLVDEMYDEFVRVIVDGRGMSETEVRELADGRIYTGSQAVATGLVDELGGLDDVIESMKEDLGADYNVIRYEHSLGLYDFFSMSTNRLLSPSYELQSIERLLNQSNTPTLQYLYAE
What is the function of this protein?
Digestion of the cleaved signal peptides.
What are the official names of this protein?
Putative signal peptide peptidase SppA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
Protein: VBA1_YEAST
Sequence: MQTLDETSNLLPPPEEAEAPPLEQKFHEYNLALPKFPILFSLWLGSFLSSLDSTIVANIMNRVAEEFSESSKKQWIATSFLLTNTAFQPLYGKLSDITGRKSALLTAQFFFGLGCLLTCFARNVTEFSIARAICGIGAGGLNAISSIAVSDICTARERGVYQGYANIVFGFGQLLGAPLGGVFIETIGWRALFGIQVPVIMLCSVLAIKNINIKLFHVPPMKERYTLKNLSRIDIFGSLSLVATISGVLFLCSSQLNKLYLALFTIGSFIVFILVERYYATEKILPFELLTRSFCLSSAVTVISSFVVFGEIFRSPIYLQLLQNISVTKTGLFLIFPSISVAVGSLVTGWVLRNTKINLAHCAYQIIFGGMIMQLLGLGLGYFLLSHLNPDYTIYDMLESITFRSNSIWWKLIYVFASVLVSFGYACLLVATLVSIVFTVEKSQQGTMTGVFYLWRSIGNVLGASLTLVSYENSLSSMLWNYMFKTKRDDEYHFTKKQYYSLINDSSYLRGPNFPTDIFVRILDVYKKAFLISYIPNIALAAVGIVLSLYLVKHTYKRSSSS
What is the function of this protein?
Transporter required for vacuolar uptake of at least histidine and lysine.
What are the official names of this protein?
Vacuolar basic amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: SECA_PARMW
Sequence: MLKLLLGDPNARKLKRYQPIVSDINLLEEDIFPLSDDALRDKTAAFQEQLASAGSLENQRPILDEILPEAFAVVREAGKRVLGMRHFDVQLIGGMVLHEGQIAEMKTGEGKTLVATLPSYLNALTGRGVHVVTVNDYLARRDAEWMGQVHRFLGLSVGLIQQDMRPEERRRNYNCDITYATNSELGFDYLRDNMAADISEVVQREFQYCVIDEVDSILIDEARTPLIISGQVQRPQEKYQQAAQVAQALTRAAEMGKDGIDPEGDYEVDEKQRSCTLTDEGFAKAEQMLGVQDLFDPQDPWAHYITNALKAKDLFVKDVNYIVRDGEAVIVDEFTGRVMPGRRWSDGQHQAIEAKEALPIQAETQTLASITYQNFFLLYPRLAGMTGTAKTEEVEFEKTYKLETTIVPTNRVRARQDWPDQVYKTETAKWRAVANETVDIHKNGRPVLVGTTSVEKSELLSALLAEQEIPHNLLNAKPENVERESEIVAQAGRAGAVTIATNMAGRGTDIILGGNSDYMARLKLREVLLGRLVKPEENHKPPVPLQRNAAAGFSEAPTASATPSRDSLYPCVLTDDTDQTLAQLARDLVKAWGDRALTLIELEERIATAAEKAPTDDPNIQALRAATARVKGEFDAVVKQEEQRVREAGGLHVIGTERHESRRVDNQLRGRAGRQGDPGSTRFFLSLGDNLLRIFGGDRVAGLMNAFRVEEDMPIESGMLTRSLEGAQKKVETYYYDIRKQVFEYDEVMNNQRRAVYSERRRVLDGRALKKQVIGYGERTMNEIVEAYVNPDLPPEEWDTAQLVAKVKEFVYLLEDLTPEQVQGLGMDELKAFLQEQLRNAYDIKEGQVEQQRPGLMREAERFFILQQIDTLWREHLQAMDALRESVGLRGYGQKDPLIEYKNEGYDMFLEMMTNMRRNVIYSMFMFQPAAPQQSQV
What is the function of this protein?
Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: IF2_SALA4
Sequence: MTDVTLKALAAERQVSVDRLVQQFADAGIRKSADDSVSAQEKQTLLAHLNREAVSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEEQAKREAQQKAEREAAEQAKREAAEKAKREAAEKDKVSNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTATPEPVEDTSDYHVTTSQHARQAEDENDREVEGGRGRGRNAKAARPAKKGKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIESESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGTIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGH_PSESY
Sequence: MSNSLPVPMSLNEYLAHLPMSDEQRAELAGCTTFAELHERLSAQPVTDPAEAAQASVGRRLTLTPRDQLEDAEMLGVDASGRLCLKATPPIRRTKVVPEPWRTNILVRGWRRLTGKGNPPKPEHDDLPRDLPKARWRTVGSIRRYILLILMLGQTIVAGWYMKGILPYQGWSLVSLDEITRQTFVQTALQVMPYALQTSILLLFGILFCWVSAGFWTALMGFLELLTGRDKYRISGASAGNEPIEKGARTALVMPICNEDVPRVFAGLRATFESVAATGDLDRFDFFVLSDTNETDIAVAEQQAWLDVCRETKGFGKIFYRRRRRRVKRKSGNLDDFCRRWGGDYRYMVVLDADSVMSGECLTSLVRLMEATPDAGIIQTAPRASGMDTLYARMQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRMKPFIEHCALAPLPGKGAFAGAILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFFFLVLSTALLAVNTLMEPTYFLEPRQLYPLWPQWHPEKAVALFSTTIVLLFLPKLLSVILIWAKGAKGFGGKFKVTVSMLLEMLFSVLLAPVRMLFHTRFVLAAFLGWAATWNSPQRDDDSTPWIEAVKRHGPQTLLGACWALLVFWLNPSFLWWLAPIVVSLMLSIPVSVISSRTNLGVKARDEKFFLIPEEFEPPQELISTDRYTYENRWHALKQGFIRAVVDPRQNALACALATSRHVRLSRLKWCVWSVSIRHSRSVRQNSAIRNA
What is the function of this protein?
Pathogenicity factor.  Required for both the expression of disease symptoms on host plants and the development of the hypersensitive reaction on non-host plants.
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TNFA_SAISC
Sequence: MSTESMIQDVELAEEAFSKTQGPQGSRRRWFLSLFSFLLVAGATALFCLLHFGVIGPQREEQSSRDFSPINSLALAVRSSSRIPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSDGLYLVYSQVLFKGQGCPSTFTLLTHSISRIAVSYQAKVNLLSAIKSPCQRETPRGAKTHPWYEPIYLGGVFQLEKGDRLSAEISPPDSLDLAESGQVYFGIIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: GGC1_YEAST
Sequence: MPHTDKKQSGLARLLGSASAGIMEIAVFHPVDTISKRLMSNHTKITSGQELNRVIFRDHFSEPLGKRLFTLFPGLGYAASYKVLQRVYKYGGQPFANEFLNKHYKKDFDNLFGEKTGKAMRSAAAGSLIGIGEIVLLPLDVLKIKRQTNPESFKGRGFIKILRDEGLFNLYRGWGWTAARNAPGSFALFGGNAFAKEYILGLKDYSQATWSQNFISSIVGACSSLIVSAPLDVIKTRIQNRNFDNPESGLRIVKNTLKNEGVTAFFKGLTPKLLTTGPKLVFSFALAQSLIPRFDNLLSK
What is the function of this protein?
Mitochondrial GTP/GDP transporter required for GTP uptake and GDP exit from mitochondria.  Involved in mitochondrial iron transport and essential for mitochondrial genome maintenance.
What are the official names of this protein?
Mitochondrial GTP/GDP carrier protein 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UFL1_CULQU
Sequence: MTSDWDEIKRLASDFQKAQLTTSLQRLSERNCVEVVSLLIEKGLLEVIYTTDGKEYLTQVHLKQEVRDEMFVRGGRVNLVDLSKALTVDFEKVQVVAEQIVVEDRSVKFILGQLIEQFYMERVASEINEKLAQVGEINVADLTVQYDLPADFILNNIILRHLNKTIMGKQDSSNANIFFTQSYVARSKAKVRGALAAITKPTPVSAILAQCGIPDRLFNLLVNEVATLGSVTSRTPGALYIPHIYTKTQVEWVQNFYRQNGYLEHDSVAGLGVTDVKNFIVNQLPNEKIVHLKKCSVGEKLIEQVASSLEECISTSTYLDVSTVLPSIMSDEDVDQLLTIVLTAPMQKQVLIFNSTILTTKFVEDMIKPCYDIAVENAKKSVDSGTYQQYMAEKMMKHQDVIPDKESAENKADKRDERRKKAAGGKAGGGAQGRETKTKSTKKHARGHRGNVSDSDEDFGPAEKSAGGKKGAKEASIELITVKDISKVLHGGLEEEGLEDLAKQLAQHYYPQFSRLALAKAHELYEISLHQNNQNRRQTHANLQDKLNNLFNDIRLYEKGIKLLPADVQPQLVKYLLKSLGTDFCNEIFFYVAAECNLNSNGTTLTVEQRNKIAADCGQEYRGALQALNKATASSAAVDDFLVVAENSLQACSMILKKIDKKKDRNLILCHKHGLLEQLANCSDPALVLHLAVLILFTISTQSMLHASGRHVSAILSFLQPALAPEQAQTLTTYHDLVLKLLSVENASDDSKADADEVKQQLEKLTPTVKDIAGNYKKAGLTSAE
What is the function of this protein?
E3 UFM1-protein ligase that mediates ufmylation of target proteins.
What are the official names of this protein?
E3 UFM1-protein ligase 1 homolog, E3 UFM1-protein transferase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UFL1 family.
Protein: RL36_OCEIH
Sequence: MKVRASVKPICEKCKVIKRKGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RCEL_RUBGI
Sequence: MAMLSFEKKYRVRGGTLVGGDLFDFWVGPFYVGFFGVTTLFFSVLGTALIIWGASQGPTWNLWQISIAPPDLKYGLGVAPLMEGGLWQIITVCAIGAFVSWALREVEICRKLGMQYHVPIAFSFAILAYVTLVVIRPILMGAWGHGFPYGIFSHLDWVSNVGYQYLHFHYNPAHMLAITFFFTTTLAMSMHGGLILSAANPKKGEPMKTTDHEDTFFRDAVGYSIGSLGIHRLGLFLALSAAFWSAVCIVISGPFWTRGWPEWWGWWLNLPIWSQWPLK
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein L chain, Photosynthetic reaction center L subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HCHA_SHISS
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAD
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS28_PYRFU
Sequence: MAEDEGYPAEVIEIIGRTGTTGDVTQVKVRILEGRDKGRVIRRNVRGPVRIGDILILRETEREAREIKSRR
What are the official names of this protein?
30S ribosomal protein S28e, Small ribosomal subunit protein eS28.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: PSNB_DICDI
Sequence: MSSDNNNDPFDLNEDGHDYFNRVSTTTSPNRQSINSSPKQSSPKSTNNNDDKNNIILDLNDNNNDNNNTNNYNDEDIDVDNKNKFENKDNTYNSNGGSNNKNKNKKKDNKSNNSSDNEEADENTSLISDSEPLLNKKEKDDEQIEIENLDGEDYDDEVSLQDFSSMIVSIIIPVSITMMAVVFFVKYLNNQTLYASTLSYTIAGGSSGGGSGADSITGNSFVDSLIVAGIVLGMIIVTTVAFVLLYKYRCLKILYGWLFLSVGMMLGSFGTTFFQAMLSAANLPLDYITFAFLIFNFTVCGIIGVFWYAHQYVNQLYLVIISVLMAISLTRLPQWTIFTLLVIVAIYDLFAVLCPRGPLKVLVELSQERNENIPALVYETGKGSDSNLKLGLGDFIFYSLLISRAALVHMSCVFSTFIAILTGLFLTLLCLAIFKKALPALPISIFLGILFYYLSNNFLTPFIEALTLSQIFV
What is the function of this protein?
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.  Requires the other members of the gamma-secretase complex to have a protease activity (By similarity).
What are the official names of this protein?
Presenilin-B, PS-B.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: ARGR_ANADF
Sequence: MTHQRHRREVVARLLRARRIGTQEELLEALRAGGIEATQATLSRDLAQLGARRVSRPEGGTVYELPAGAAERDGLATLRGLVSEVASNASLVVIRTHPGSAPAIARAIDLAGLPDVLGTIAGDDTIFVAPAGELRARKLATRLADLLGAPVAGEGPAQ
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_STRPS
Sequence: MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREGIMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIVLNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEFIDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKYDDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDIDKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADTLEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQEETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTVALKQLEELSLQVEEDETNKTN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_PSEFS
Sequence: MAGAKEIRSKIASIKSTQKITSAMEKVAVSKMRKAQMRMAASRPYAERIRQVIGHLANANPEYRHPFMIERAVKRVGYVVVSSDRGLCGGLNTNLFKALVKDMAVNRENGVEIDLCVVGSKGAAFFRNFGGNVVAAISHLGEEPSINDLIGSVKVMLDAYLEGRIDRLSVVSNKFINTMTQQPTVEQLIPLVATPDQELKHHWDYLYEPDAKELLDGLMVRYVESQVYQAVVENNAAEQAARMIAMKNATDNAGDLISDLQLIYNKARQAAITQEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS4_LACP3
Sequence: MSRYTGPRWKQSRRLGLSLSGTGKELARRPYAPGDHGANNRRKISEYGQQLREKQKLRWMYGLNERQFQNLFLRAGKIKEGTHGDNFMILLETRLDNLVFRLGLASSRPQARQLVNHGHITVDGKRVDIPSYEVEPGQVIALRERSQNLAIVNEAIENTVSRPAYVTFDDTKKTGSLVRLPERGELEPEVDESLVVEYYNQKL
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CLPP1_HALH5
Sequence: MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGTAIDDNVANSIVAQLLFLQAEDPDKDISLYINSPGGSITAGMAIYDTMQYIKPNVSTICIGMAASMGAFLLAAGAKGKRFALPNSEVMIHQPLGGTRGQASDIEIHTRRILEMRETLNRILAERTGQPLEQIAKDTDRDNFMTAEKAREYGLIDKVIETTK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.  ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW.  This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
Protein: FBLN7_HUMAN
Sequence: MVPSSPRALFLLLLILACPEPRASQNCLSKQQLLSAIRQLQQLLKGQETRFAEGIRHMKSRLAALQNSVGRVGPDALPVSCPALNTPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPCQNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTAAPEGSVAGDSAFSRAPRCAQVERAQHCSCEAGFHLSGAAGDSVCQDVNECELYGQEGRPRLCMHACVNTPGSYRCTCPGGYRTLADGKSCEDVDECVGLQPVCPQGTTCINTGGSFQCVSPECPEGSGNVSYVKTSPFQCERNPCPMDSRPCRHLPKTISFHYLSLPSNLKTPITLFRMATASAPGRAGPNSLRFGIVGGNSRGHFVMQRSDRQTGDLILVQNLEGPQTLEVDVDMSEYLDRSFQANHVSKVTIFVSPYDF
What is the function of this protein?
An adhesion molecule that interacts with extracellular matrix molecules in developing teeth and may play important roles in differentiation and maintenance of odontoblasts as well as in dentin formation.
What are the official names of this protein?
Fibulin-7, FIBL-7.
What is the protein family that this protein belongs to?
Belongs to the fibulin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: OMPA_YERPS
Sequence: MKKTAIALAVALVGFATVAQAAPKDNTWYTGGKLGWSQYQDTGSIINNDGPTHKDQLGAGAFFGYQANQYLGFEMGYDWLGRMPYKGDINNGAFKAQGVQLAAKLSYPVAQDLDVYTRLGGLVWRADAKGSFDGGLDRASGHDTGVSPLVALGAEYAWTKNWATRMEYQWVNNIGDRETVGARPDNGLLSVGVSYRFGQEDAAAPIVAPTPAPAPIVDTKRFTLKSDVLFGFNKANLKPEGQQALDQLYAQLSSIDPKDGSVVVLGFADRIGQPAPNLALSQRRADSVRDYLVSKGIPADKITARGEGQANPVTGNTCDNVKPRAALIECLAPDRRVEIEVKGYKEVVTQPQA
What is the function of this protein?
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm.  Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
What are the official names of this protein?
Outer membrane protein A, Outer membrane porin A.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: YBWC_SCHPO
Sequence: MSSKKVKYNPRKSASQNEATSASAGSKAFGFNSAKKEKLHRMALSMEAIEDVEDQSFNGKSSNLVRKRRGLDEDIDEFSSSSEDERKPARHPQSSSQKPFASSTYNVELPTSPTKITNIGQSSPRALRYLSPESQRIKNAKMKSPISTHLAKYSIHHMGTPPSKPSFLSSSVSSPASSKQKSLFQCTKDLEKRYINRVHRSSETELVQLSSIKVLDRFLSDIYLVEAEKNEEKCTVLLLKRSNTDVDNSSSLSLTLPLCKFTKNGHQVHIHPC
What are the official names of this protein?
Uncharacterized protein C651.12c.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle.