PharMolix/UniProtQA huggingface dataset:
Protein: CLPX_ALKOO
Sequence: MSRFDEKKQLKCSFCGKSQDQVRRLIAGPNVYICDECIELCQEIIQEEFDESIDLDLMDLPKPSEIKDILDQYVIGQEKAKKALAVAVYNHYKRINVEDVKSGDVELQKSNILMLGPTGSGKTLLAQTLAKIINVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDIERAEKGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIDSIIQKRTSKKSMGFGAEIESKQVLDLGSLLKQIQPEDLLKFGLIPEFVGRLPVVVTLEQLDEEALIKILTEPKNALTKQYKRLFEIDGVHLEIEEEALRLIAKKAIERKTGARGLRGIVEGIMMDTMYEIPSRDDIEKVIITAEAITENKEPKILLKEDVKPKLDKKENEESVS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PLB1_PENCH
Sequence: DITFAGVQRALPNAPDGYVPTSVSCPASRPTVRSAAKLSTNETSWLEVRRGKTLSALKDFFGHVKVGDYDVGAYLDKHSGNSSSLPNIGIAVSGGGWRALMNGAGAVKAFDSRTDNATATGHLGGLLQSATYISGLSGGSWLLGSIYINNFTTVDKLQTHEAGSVWQFGNSIIEGPDAGGIQLLDSAGYYKDLADAVDGKKKAGFDTTLTDIWGRALSYQMFNASNGGLSYTWSSIADTPEFQDGDYPMPFVVADGRNPGELVIGSNSTVYEFNPWEFGTFDPTIFGFVPLEYLGSKFEGGSLPSNESCIRGFDSAGFVIGTSSSLFNQFLLQINTTSLPSFIKDVFNGILFDLDKSQNDIASYDPNPFYKYNEHSSPYAAQKLLDVVDGGEDGQNVPLHPLIQPERHVDVIFAVDSSADTDYFWPNGTSLVATYERSLNSSGIANGTAFPAVPDQNTFINLGLSTRPSFFGCDSSNQTGPSPLVVYIPNAPYSYHSNISTFQLSTDDAERDNIILNGYEVATMANSTLDDNWTACVACAILSRSFERTGTTLPDICSQCFDRYCWNGTVNSTRPESYDPAFYLADNSMASVSLPTMLSTVVAAGLAMLILV
What is the function of this protein?
Catalyzes the release of fatty acids from lysophospholipids.
What are the official names of this protein?
Lysophospholipase, Phospholipase B.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: DPNP_EMENI
Sequence: MSYERERYIAELAVQRATILTQKVFNEKAKGTVSKDDKSPVTIGDFGAQALIIQAIRKNFPNDEIVAEEEASTLREDKALSAEIWRLVKDIKLEDAESNELLGGSLPSEEAMLDIIDEGKSAGGPKGRIWALDPIDGTKGFLRGGQYAVCLGLLEDGDVKVGAIGCPNLPVDDAATISSSIGVDQNSGAGNGVLFSAIKGAGSVSRPLTSGARAESKSISMRPVPDIAQAVFCEGVEAGHSAQGDNAAVAQLLGITSPSVRLDSQAKYCSIARGAGDIYLRLPVKKDYQEKIWDHAAGDLIVREAGGQVTDIYGQTLDFSKGRTLAANKGVVAAPKAIQDEVISAVKKVLKL
What is the function of this protein?
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.  Regulates the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity).  Involved in osmoadaptation.
What are the official names of this protein?
3'(2'),5'-bisphosphate nucleotidase, 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase, DPNPase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: CHLN_ADICA
Sequence: MKTPETLAFECETGNYHTFCPISCVAWLYQKIEDSFFLVVGTKTCGYFLQNALGVMIFAEPRYAMAELEEGDISAQLNDQKELEKICLQIRDDRNPSVIIWIGTCTTEIIKMDLEGIAPKLEKQIGIPIIVARANGLDYAFTQGEDTVLAAMAHRCPEYKHCTTNLKNRTDEMARIDNHTTNKSPFEASKLTRFNLVLFGSLSSSIASQLNLELKRQSISVSGWLPSQKYEELPGLGEGIYVCGVNPFLSRTATTLMRRRKCKLVGAPFPIGPDGTRAWIEKICSVFDIKSYGLENRESEIWENVKDYIQVINGKSVFFMGDNLLEISLARFLIRCGMIVYEVGIPYMDRRYQAAELLFLQHTCRKMKTPLPRIVEKPDNYGQIQRMHELKPHLAITGMAHANPLEARNIDTKWSVEFTFAQIHGFSSVRDILELVTRPLRRRGVITPGFRSLSKQTTGD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TCTP_SCOMX
Sequence: MIIYKDLLSGDEMFSNIYKIRELEGGILLEVEGKRITRTEAIDDSAFGANPSAEELSEANEAAVSSGVDIILNHKLISTLYNKKQYSAYIKKYMKDLKTKLEETNPERVDAFVAGAVGAVKMILGKFKDFEFYTGESMNHDAMVGLLDYREDGITPIMLFFKDGLEIEKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF6_RABIT
Sequence: MRTLALLAAILLVTLQAQAELHSGMADDGVDQQQPRAQDLDVAVYIKQDETSPLEVLGAKAGVFCTCRGFLCGSGERASGSCTINGVRHTLCCRR
What is the function of this protein?
Microbicidal activity.
What are the official names of this protein?
Neutrophil antibiotic peptide NP-5, Microbicidal peptide NP-5.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EXOS9_RAT
Sequence: MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLLERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGEEVTLYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVFRCSKIAGVKVAEITELIQKALENDQRVRKEGGKFGFAESIANQRITAFKMEKAPIDTSNIEEKAEEIIAEAEPPPEVVSKPVLWTPGTAQIGEGIENSWGDLEDSEKEEEEEGGIDETVILDDTKMDTGEVSDIGSQGAPIVLSDSEEEEMIILEPEKSPKKIRAQTSANQKAPSKSQGKRRKKKRTAN
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  EXOSC9 binds to ARE-containing RNAs (By similarity).
What are the official names of this protein?
Exosome complex component RRP45, Exosome component 9.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus. Nucleus, nucleoplasm. Note=Colocalizes with SETX in nuclear foci upon induction of transcription-related DNA damage at the S phase (By similarity).
Protein: HEM3_HAES1
Sequence: MSINKTLKIATRQSPLALWQANYVKNRLQQRYSHLSVELVPIITKGDVILDTPLAKIGGKGLFVKELENALLNGEADIAVHSMKDVPMQFPKGLELSVICPREDPRDAFVSNKYRTLDELPQGAIVGTSSLRRQCQLKNWRADLDIRSLRGNVGTRLNKLDQGDYDAIILASAGLIRLGLTERIRSFIEIDTILPACGQGAVGIECRVDDRDVQSLLMPLADQTTTYCVLAERAMNFHLQGGCQVPIGAYAILENNQLYLRGLVGDVHGSQILSAEGQFELSLDFESSQSAVQKAEELGVSIAEQLLQQGADKILQAVYQS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: FADA_SHIF8
Sequence: MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEHIGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGISREMQDAFAARSHARAWAATQSAAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEALATLRPAFDPVNGTVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCDPSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBD_AERPE
Sequence: MFEWLARALYPEPEVLAAGLAVGLMLDLAYPEHRGLALKLHPVHTSYIMALRLVRPGAGRAWGAAIWLLTISSHMMVYASLLAASYLVHPALHTLAVGVIVKLSMPLRLLLDTCIKASRMAAAGRVECSRRLVQGIVRRDLSGEPLGRVLSACIESTAESLVDGYTSPLTYYILLGPLGALLQRLSNTLDGAVGFKTPLLYRQGWFSAKADTLLNFIPARLTAVMVALAAPLAGASTLGSLRCIARCARLLESVNAGYPISAFAGALDVRLEKKGFYIVNGGAPYPGWRDGLKASRLAVSAASLYTVLAALAIALGGGAG
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Probable cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IDI2_VIBC1
Sequence: MAPQSNRKDLHLDAVLHHDMNMKSKTAGFESVEFEHCALPECDFNAVDLSSEFLGHSLALPFLISSMTGGAKDAEIINCRLAEAASEMGIAMGVGSQRVSLEDSLHSGLGKTIRDLAKGVPLYSNLGAAQLMDKQRFDNAQRAVDFIQADALFVHLNPMQEAFQQNGDHDWIGVLKSIEQLKQRVDVPMIIKEVGFGISGVVAKQLVEAGVDAIDVAGAGGTSWSAVEGYCQTDNKMQRAAELFRDWGIPTAKCLEQIRGQYPDLPLIASGGVYNGLEAAKAVHLGANLVGQAGAVLKAATISTESIVEHFEQMALELRLACFGTGSANLRALTQARRL
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTD_SALDC
Sequence: MTELPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRTQYMAAMTFVTLPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAMATFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILLYLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPH_ORYSA
Sequence: MNPLIAAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PREB_MOUSE
Sequence: MGRRRGVELYRAPFPLYALRIDPKTGLLIAAGGGGAAKTGIKNGVHFLQLELINGCLSASLLHSHDTETRATMNLALAGDILAAGQDAQCQLLRFQVHQQKGSKAEKSGSKEQGPRQRKGAPPAEKKSGAQVHPEGVELKVKNLEAVQTDFSNEPLQKVVCFNHDNTLLATGGTDGHVRVWKVPSLEKVLEFKAHEGEIGDLTLGPDGKLVTVGWDFKASVWQKDQLVTQLQWQENGPASSNTPYRYQACRFGQVPDQLGGLRLFTVQIPHKRLRQPPPCYLTAWDSSTFLPLRTRSCGHEVISCLSVSDSGTFLGLGTVTGSVAIYIAFSLQRLYYVKEAHGIVVTDVTFLPEKGCGPKLLGPHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQTAFPGFL
What is the function of this protein?
Was first identified based on its probable role in the regulation of pituitary gene transcription.  Binds to the prolactin gene (PRL) promoter and seems to activate transcription.
What are the official names of this protein?
Prolactin regulatory element-binding protein, Mammalian guanine nucleotide exchange factor mSec12.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus. Note=Concentrates at endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER).
Protein: ECO1_DEBHA
Sequence: MKRDITQLLSPELSQSSSRNDKKRKPTNSNKKVQTVLNFPSSSPNASQSTTCPTCGMTYYSHVSKDNDVHNKYHFNFINGIPWPTSFCNNVLERFIVVDHTTGKAKGTSKSKKSQAASKETLVMTIDRRASKQVKRVEEILKVVNGELNAASDGKAWQKDHKGPIQGRAFIVVIDGRAIGICTTEPIQDVDQQCRWIIHRTQALVPNQVNRSIKLGISRIWIAPKWRRYGLARRLLDIVLVHSVYGIVLDKKEIGFSQPSFSGGLLAKSFNGVTHKSGEILIPVYLEE
What is the function of this protein?
Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together.  In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase.  Acts by acetylating the cohesin complex component SMC3 (By similarity).
What are the official names of this protein?
N-acetyltransferase ECO1, Establishment of cohesion protein 1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ECO subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUDI_ECO55
Sequence: MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVESGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSANREVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: CINA_FINM2
Sequence: MKVQIIAVGTELLLGDTLDTNSNYLSIKMRELGFDVYKRVVVGDNYDRLYKEIEEGLQQNDLIITTGGLGPTEDDITKKCCCDCLGKKMVLNEKSYAKLRKYFNEDEKAIQGNIKQCMFPEDAIVFENFNGTADCALIENNGKRILFLPGPPAEMKPIYENQVQQVLEQFATDCIISETLNISILGEWDMNERVKDIIESSNNPTVAPYFKKDKRILRITAKASDRQTALDMIAKKKQELRDRLGMYVFGENDETIEESVYKVLKEHDLSIMTSESITGGMIASKLVNVSGVSDYLKRSLVVYSNEAKIELLGVKAETIDTYGVVSENVAFEMVERMFEKFNVDCSISTTGFASGENAGLVYVGLGYKNTIKTLKLQLHGERNKIRNRVSNRALAELRLMILENVSRETF
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: SECA_TRIEI
Sequence: MFKKLLGDPNARKLKKFQPWVTDINILEEDIQKLSDEELKAKTGEFRQALEKAKTKDEEKAILEEILPEAFAVVREAGKRVLSMRHFDVQLLGGIILHQGQIAEMKTGEGKTLVATLPAYLNGLTGKGVHVITVNDYLARRDAEWMGQVHRFLGLSVGLIQQGMNPEERKKNYTCDITYATNSEVGFDYLRDNMATNMEEVVQRPFNFCIIDEVDSVLVDEARTPLIISGQVERPSEKYIKAAEIAAALSKEKEHYEVDEKARNVLLSDEGFAEAEQLLAVQDLYNPEDPWAHFVFNALKAKELFIKDVNYIVRDDEVVIVDEFTGRVMPGRRWSDGLHQAIEAKERVDIQPETQTLATITYQNFFLLYPKLSGMTGTAKTEEAEFEKIYNLQVTIIPTNKPTGRKDLSDVVYKTEVGKWKSIAQECAEMHKEGRPVLVGTTSVEKSELLSRLLGEGKIPHQLLNAKPENVERESEIVAQAGRGGAVTIATNMAGRGTDIILGGNAEYMAKLKLREYLMPKVVKPEDDDGLGMVRVSGLKKSHVAKGFDPQQKVKTWKVSPQIFPVKLSQETEGMLKLAVNLAVKEWGERALPELVVEDKVAIAAEKAPTTEPVIEKLREVYNLIRQEYENYIEREHNQVVGCGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSTRFFLSLEDNLLRIFGGDRVAGMMQAFGVEEDMPIESGLLTRSLEGAQKKVETYYYDMRKQVFEYDEVMNNQRRAIYAERRRVLEGRDLKEQVIKYAEQTMDDIVEAYINPELPSEEWELDKLVEKVKQFVYLLADLTPEQLFDLSMEDIRTFMHEQVRNAYDIKEAQVNQIRGGLMRDAERFFILQQIDTLWREHLQQMDALRESVGLRGYGQKDPLIEYKSEGYELFLDMMTDIRRNVVYSLFQFQPQPAVQTTAAETV
What is the function of this protein?
Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: RL22_SHISS
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MTNA_THET8
Sequence: MDRVLPFRFAEEEGVFWLLDQRRLPQEEVYVPVRTAREMAQAIRDMVVRGAPAIGVSAAFGMVLAHLAGEDLEEADRRLRASRPTAVNLFHALDRMRPFWGDLAGSLLEARRIWREVEETEAAISRHGAQVLWGQVLTHCNTGPLATGGYGTALGAIVEAYRLGRVRHVWVDETRPYLQGARLTAYELQKAGVPATLITDGMAGWLMARGAVDAVVVGVDRMALNGDFANKVGTYALAVLAHHHGIPFYAALPLSSVDPRLASGEGIPIEERSPEEVVAFRGVRIAPEGFPAYHPAFDVTPHRYLTGIITEKGVLYPPFAEGLRRALGLD
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: HIS7_SACEN
Sequence: MTAMQPGTRVGRVERTTRESSVLVELDLDGTGQVDIDTTVPFYDHMLTALGTHAAFDLKVKSSGDVHIDAHHTVEDTAIVFGQALRQALGGKLGIRRFGDAWIPMDETLAHAAVDVSGRSYCVMTGEPEQYNSFTIGGNYPFVLNRHVFESIAFHSQINLHVRVIHGRDPHHIAEAQYKAIARALRAAVEPDPRFSGVVPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATAD3_BOVIN
Sequence: MSWLFGIKGSKGEGTGPPLPLPPVQPGGEGSGDGGAGDRPGPKDKWSNFDPTGLERAAKAARELEHSRHAKEALSLAQMQEQTLQLEHQAKLKEYEAAVEQLKGDQIRVQAEERRKTLSEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEALRRATVEREMELRHKNEMLRVEAEARARAKAERENADIIREQIRLKAAEHRQTILESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLAVGIYSAKNATSVAGRYIEARLGKPSLVRETSRITVLEALRHPIQVSRRLLSKPQDALEGVVLSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGRDGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSSKFMLVLASNQPEQFDWAINDRIDEMVSFELPQREERERLVRMYFDKYVLKPATEGKQRLKLAQFDYGKKCSEIAQLTEGMSGREISQLAVAWQAMAYASEDGVLTEAMMDARVQDAIQQHRQKMQWLKAEGSQPPTLRTQAE
What is the function of this protein?
Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level.  May play an important role in mitochondrial protein synthesis.  May also participate in mitochondrial DNA replication.  May bind to mitochondrial DNA D-loops and contribute to nucleoid stability.  Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis.  Involved in mitochondrial-mediated antiviral innate immunity.
What are the official names of this protein?
ATPase family AAA domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid. Note=In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane. The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (By similarity).
Protein: RECA_ACIBY
Sequence: MDENKSKALQAALSQIEKQFGKNTVMRLGDNTVQAVEAVSTGSLTLDIALGIGGLPKGRIIEIYGPESSGKTTMTLQAIAQCQKSGGTCAFIDAEHALDPQYARKLGVDIDNLLVSQPDNGEQALEIADMLVRSGAIDLIVVDSVAALTPKAEIEGEMGDSHMGLQARLMSQALRKITGNAKRSNCMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGQVKEGDEIVGSETKVKVVKNKMAPPFKEAIFQILYGKGTNQLGELVDLAVQQDIVQKAGAWYSYQGNKIGQGKNNVIRYFEENTQIAEEIERNIREQLLTTGTNGAVQIEDEEEPDLLLES
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTL_ECOK1
Sequence: MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSALFLAGRFLQGLGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWTMATMGIALLMLSLFILKETRPAAPTTSDKPRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA
What is the function of this protein?
Confers resistance to chloramphenicol.
What are the official names of this protein?
Multidrug resistance protein MdtL.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CPLN2_HUMAN
Sequence: MARPPVPGSVVVPNWHESAEGKEYLACILRKNRRRVFGLLERPVLLPPVSIDTASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRRLADGRTLDGRAGLADVAHILNGLAEQLWHQDQVAAGLLPNPPESAPE
What is the function of this protein?
Potential effector of the planar cell polarity signaling pathway.  Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes.  Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia.  More generally involved in exocytosis in secretory cells (By similarity).
What are the official names of this protein?
Ciliogenesis and planar polarity effector 2, REM2- and Rab-like small GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: Y334_YERPN
Sequence: MLIIISPAKTLDYQSPLATTKFSQPEMLDKSQALIEICRELTPAQISSLMGISDKLAGLNAARFSEWQPDFTPANARQAILAFKGDVYTGMQAESFSEADFDFAQQHLRMLSGLYGLLRPLDLMQPYRLEMGTKLANPRGKDLYAFWGDQITEKLNQALELQGDNILINLASDEYFKAVKPAKLSGSLIKPVFLDEKNGKYKIISFYAKKARGLMSRFIIQNKLTKPEQLVDFNLEGYEFDAGLSAKNELVFKRAEQH
What are the official names of this protein?
UPF0246 protein YPN_0334.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.