PharMolix/UniProtQA huggingface dataset:
Protein: LAR4_DROME
Sequence: MEYFLGGYVYMNGDALKIQPPVYTNVPVETAMLATNLFGATTQIAASPAAAAAAHIPLITAAAAAAAAAGAPAVAPPVAVAPVATASAAQAAVVPAQQQQQAHPHQAQILAHTHVAHQQQQQQQQQTIQQHLHQQQQQQSPHPAQHLTYGHQPALSQATAGGSGTISGGAVGPSGVVVEGQDTNEYAIMNGALGQTQDGTVVCYTTDALNNTNLVALDPQPHQIVVPVQVPVQVPVPVQLPANGSADPQQGSHNAAGGEEPNIPLDKLKQMLATQLEYYFSRENLANDTYLLSQMDSDQYVPIYTVARFNLVRKLTNDINLITEVLRESPNVQVDDKGLRVRPNRKRCIIILREISNNTPLDDVKALFSNESCPRPISCEFAANNSWYITFESDEDAQKAYKYLREEVKEFQGKPIMARIKPKSFINRIQAVPKNGYRLTSPPTANVFDPAGAGGATVSYAAAQQPRYLYTNGAAIAAPASVQYSNPVLIPIPQNQFYPGLVAGPWPPGTVAATTAHGQNFYELGGNIFTTNPLPPQPVTAGFAQAPPPTSQAMVTPKPQGGGRYNNNHRGNPNNVGGANSGPRAESRSKPPRSTPSASHIQGGNIMPIQITAPIPGGMVSVVPTNIVQDPLQPAPLQQQPQQVIQQIQQQPSSSAQQQQAATVQMNNTTRHYPIKSNWKGGMQKNLDKSYSGGVATHHHYTTQVQALPAHSHHLQAQQQLQGQTQQQHYQLASSSAASAPQVTYVTTAPAPQQPGQHQHHLVVQQTQPQQQQQQQQVVLQQQQVQVQELQEAGDGVEHSSHAMQQVNRSSNMSASSSSSLATSMSKEPLQWQNRPRRRRRDEEGGINYSPGGRVGLYGSSPSNPHPQQHLMSSSTGSNVQSAGGTDGGGASHRGGERQSHYNTIHDVPPPQHRGNYKGNNYNPHYHAQHSSMASGSHHHHHHNALSSQQQQHHLTTGTGQQGSGHHYHHHHHHNSIGSNVGNSGGLGVSSGGSGGGGSGGGSGSNSLSGGSNERGIHHSSLGYQGHQHQHQQQQQQQQQQQQQQPAAPVQPPQFDLEDAAFPPLPATSATAPHTPQATGGASLHNSTTSSSSSTGLGQKQTLHQQQQQAPQQHQVLSSSVESAGGDEQRSSNQQGIETSNIHLANSSTANNWVENRLSDVVRTGGGGGGGGKGKARKDNRHPQGQNQPHMAPNYQQHQPRNPPVSPTPALGAEYGIQIQEGNNTKNVTKQSSSNNNSIHVIKCQTPNINASSKEEAAGAQQQQQQQLDKSNKTEDEMHPKQPSQQRLVEGYVQQQQLPLLAAHNEYSAALAAGAGACSVVEGGLTTSLAECSLGQHKKPPSVAALHAKKDANLLEKGASKHKSVATSTSTENLSAAATASKLSYAQVAQHHKAAASSDSKETGSGGSTGTLSPTGSHKMDLVFGDPAVVVAAVEKSGLATVSTEKRVAGGASPAALIGKPAGGLPATNTTQGSSAVVVSAKEKDNRPNASVRPLSKEKQQQHYGSATEHNTNANIGLGASGNRKSRANNS
What is the function of this protein?
Probable RNA binding protein.  Negatively regulates myc at the protein level, via an unknown mechanism, and may therefore have a role in growth.  Has no effect on myc mRNA levels.
What are the official names of this protein?
La-related protein Larp4B, La ribonucleoprotein domain family member Larp4B.
Protein: CCMF2_ARATH
Sequence: VDTGREQAKRVVRNGKKETTTLPLCWTAGANTVVSDQDQEPIRIWILTCWWFLTVGILLGSWWAYHELGWGGWWFWDPVENASFMPWVLATACIHSVILPFLHSWTLFLNIVTFLCCVLGTFSIRSGLLASVHSFATDDTRGIFLWWFFLLMTGIFMILFYQMKQQASVRRTYKKEMVVARSTLVHLRHSARAQPRPVMLWKN
What is the function of this protein?
Forms a complex with CCMFC, CCMFN1 and CCMH that performs the assembly of heme with c-type apocytochromes in mitochondria.
What are the official names of this protein?
Cytochrome c biogenesis CcmF N-terminal-like mitochondrial protein 2, Cytochrome c biogenesis orf203.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VEGFA_HORSE
Sequence: MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGEHKTHEVVKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTAEFNITMQIMRIKPHQSQHIGEMSFLQHSKCECRPKKDKARQENPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
What is the function of this protein?
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth.  Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.  Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity).  Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).  Also binds the DEAR/FBXW7-AS1 receptor (By similarity).
What are the official names of this protein?
Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Protein: ASR5_ORYSJ
Sequence: MAEEKHHHHLFHHKKDDEPATGVDSYGEGVYTSETVTTEVVAGGQDEYERYKKEEKQHKHKQHLGEAGALAAGAFALYEKHEAKKDPENAHRHKITEEIAATAAVGAGGYAFHEHHEKKKDHKSAEESTGEKKHHLFG
What is the function of this protein?
May function in gibberellin signaling pathway downstream of GID1 and SLR1.  May be involved in the regulation of plant growth in the basal region of leaf sheaths (Probable).  Involved in tolerance to aluminum (PubMed:22676236, PubMed:24253199).  Regulates the expression of different genes that collectively contribute to the protection of the cell in response to aluminum stress (PubMed:22676236, PubMed:24253199).  Binds to the promoter and regulates the expression of target genes involved in aluminum stress response.  Binds to the promoter of STAR1 gene, which encodes an ABC transporter required for aluminum tolerance (PubMed:24253199).  Involved in drought tolerance.  Plays a positive role in response to drought stress response by regulating abscisic acid (ABA) biosynthesis, promoting stomatal closure, and acting as chaperone-like protein that possibly prevents drought stress-related proteins from inactivation (PubMed:27420922).
What are the official names of this protein?
Abscisic stress-ripening protein 5, OsASR5.
What is the protein family that this protein belongs to?
Belongs to the abscisic acid and water stress-induced protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y1711_SODGM
Sequence: MEIRVFRHDDFEEVITLWERCDLLRPWNDPEMDIERKLNHDPDLFLVAEVAGEVVGSIMGGYDGHRGAAYYLGVHPDYRGRGIANALISRLEKKLIARGCPKINLMVRGDNDAVISMYEKLEYEMQDSVLLLGKRLIEDQEY
What are the official names of this protein?
Acetyltransferase SG1711.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. YpeA subfamily.
Protein: RPPH_HELPS
Sequence: MLHKKYRPNVAAIIMSPDYPNTCEIFIAERIDIEGAWQFPQGGIDEGETPLEALHRELLEEIGTNEIEILAQYPRWIAYDFPSNMEHKFYSFDGQKQRYFLVRLKHANNIDLNKHTPEFRAYQFIHLKDLLKKIVPFKRQVYRQVIAYFRREGYLGC
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: EPHB2_MOUSE
Sequence: MAVRRLGAALLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDLATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRNGFYLAFQDYGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIKEKLPLIVGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQVMRAQMNQIQSVEV
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Functions in axon guidance during development.  Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex.  Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk.  In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses.  Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation.  Controls other aspects of development including angiogenesis, palate development and in inner ear development through regulation of endolymph production.  Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca.  May function as a tumor suppressor.  May be involved in the regulation of platelet activation and blood coagulation (By similarity).
What are the official names of this protein?
Ephrin type-B receptor 2, Neural kinase, Nuk receptor tyrosine kinase, Tyrosine-protein kinase receptor EPH-3, Tyrosine-protein kinase receptor SEK-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite.
Protein: TBCC1_DANRE
Sequence: MDKYTAYVWPRLEPFLVGVLPATPPSKFSMHYLRKMASYVRTRDGCFPRLGWQMWRHIACGKLQLAEDLAWLYFETFDLLMPRSAEQRLEWAEALSQCHTQKELDRQRCKLSVDTLQFLLFLYLQQLNRISLRTSLIGEEWPSPRSRSPSSSSSERDAKISSQNKNWDVQAHLTFIQTHLPELLELLVEPGQLSSSGQVLRDSHLTSEAVESLSLLLEGSVSHSRTVHPVHKLLSRSQLQSQAGFSKLSCSYSLQQFQDFLRQALCLNPFGISNCSQSGKKLSWALQVEGTLKKAKIFRNTHAAPPGSRLVLMSQVCKQTLAKDSEKLNDVNIKLHRCSEAFIYLLSPLWSVTLDKCRNSTLVLGPVRTSVHIQSCENVRVVCVAGRLTIGGSFNCTIHSLTPTRPLLLPGNASLTLGPFHTQYPTLEDHMASAGLAVVPNLWNQPLLFGVEGSAPDTGCYRIQPPSEFYPLVIPFQMDGDNCEIPCSLPEDFQKALESREKTIEEWQKTVKDAHLNKAQRRQFQALVEQKFHEWLLETGQRQELDSLLPPTITPSSSAEHWSSNQNTLKEQTHEQPTGTVC
What is the function of this protein?
May play a role in the regulation of centrosome and Golgi apparatus positioning.
What are the official names of this protein?
TBCC domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TBCC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole.
Protein: M170_ARATH
Sequence: MIQRTRNQSIMLSLPSNQSANHAILTFQPIGQSRYLLTFQPTPSIPLLQQYIISVPYLDAYSSICFPVMARIRSAKYCFFFFLVLFLNGIIATRGKAMLPTLPQKGAAFFPPKMPVPPSGPSKQHNSAPRSDFVQFFYM
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00170/AtMg00620, ORF139b/ORF139a.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RPOA_UREPA
Sequence: MRKFLKYQLDVPSINSEDKNRTVVKIAPLEIGFGDTLGNALRRICLSSIPGASMFAVKFGGYSHEFQPYEGVKEDITHIILNLKNLAIKIDELIYSEDYFNNLLIDKWPKMKINFKGPGVITAKDIVCPVGFEIVNQDLYIAEVTKPIDVEIEIFAKTGRGRVDFNTNKDFVSTLHIIATDSNYSPVLHYAYNVEMIKDSKSSMSEILTIDIATNGTISGSEAIAIAAKIMQAHLEPIVNIDKTINEMIIMREREEEEKRQNASISIDDLDLTVRAYNALKQSGINTTAELIELTKSQLEKIKNLGRKSVTEIIQKLTERSLELKKD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PER51_ARATH
Sequence: MVVMNKTNLLLLILSLFLAINLSSAQLRGDFYAGTCPNVEQIVRNAVQKKIQQTFTTIPATLRLYFHDCFVNGCDASVMIASTNTNKAEKDHEDNLSLAGDGFDTVIKAKEAVDAVPNCRNKVSCADILTMATRDVVNLAGGPQYAVELGRRDGLSSSASSVTGKLPKPTFDLNQLNALFAENGLSPNDMIALSGAHTLGFAHCTKVFNRLYNFNKTNNVDPTINKDYVTELKASCPQNIDPRVAINMDPNTPRQFDNVYYKNLQQGKGLFTSDQVLFTDSRSKPTVDLWANNGQLFNQAFISSMIKLGRVGVKTGSNGNIRRDCGAFN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 51, Atperox P51, ATP37.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YSCM_YERPE
Sequence: MKINTLQSLINQQITQVGHGGQAGRLTETNPLTENSHQISTAEKAFANEVLEHVKNTALSRHDIACLLPRVSNLELKQGKAGEVIVTGLRTEQLSLSDAKLLLEAAMRQDTAADG
What is the function of this protein?
Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function.
What are the official names of this protein?
Yop proteins translocation protein M, Low calcium response locus protein Q.
Protein: SCPA_STRSY
Sequence: MDIKLKDFEGPLDLLLHLVSKYQVDIYEVPITEVIEQYLAYIATLQAMRLEVAGEYMLMASQLMVIKSRRLLPKVVEQIDPEDDPEMDLLDQLEEYRKFKLLSEKLGEQHDERANYFSKPKLDLIYDDVQLAKDKTVIDIFLAFSKVMAEKQASLRQSHATIARDEYKIEDMMDFVRSRFETGPRLELRQLFQESQDVNEMITIFLATLELVKVHEIVLEQTETFGDIYLVRSEDESLS
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: GLDA_CITFR
Sequence: MLKVIQSPAKYLQGPDASTLFGQYAKNLADSFFVIADDFVMKLAGEKVLNGLHSHDISCHAERFNGECSHIEINRLIAILKQHGCRGVVGIGGGKTLDTAKAIGYYQKLPVVVIPTIASTDAPTSALSVIYTEAGEFEEYLIYPKNPDMVVMDTAIIAKAPVRLLVAGMGDALSTWFEAKACYDARATSMAGGQSTVAALSLARLCYDTLLAEGEKARFAAQAGVVTDALERIVEANTYLSGIGFESSGLAGAHAIHNGFTILEECHHLYHGEKVAFGTLAQLVLQNSPMEEIETVLNFCQKVGLPVTLAEMGVKDDIDGKIMAVAKATCAEGETIHNMPFSVTPESVHAAILTADLLGQQWLAR
What is the function of this protein?
Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone).  Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions.  Exhibits a rather broad substrate specificity since it can also oxidize 1,2-propanediol and 2,3-butanediol and reduce dihydroxyacetone.  Cannot use NADP(+) as an electron acceptor for the oxidation of glycerol.
What are the official names of this protein?
Glycerol dehydrogenase, GDH, GLDH.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: FB196_ARATH
Sequence: MKFGPNTTQIYIPLDLQINILLRLPVKSLLRFRCVSKLWCSIITSHDFRNRHFNITSSSAPPRLLIAFQDFYGEKLLLVSSPNPNVSSSSTSSCCVPYKDLSKVEINGRKVYNAVWGLTCFESRLKVGICNPSTRELHMFPQIKFKNYPDIFPCIMYFLGYDRIEDQYKVLAIDNLPWRLEYKVVPILRASRKDKGSPNISIIVSFDVRSETYKNSNVPSKLLPMDTSDNFWTANCNCFIGDKTLINYNGKIGVVEKPQHGRFRMWVVEDAEKEEWSMNTFYLPQSASGLDFKVMNTFYTGEICLVTEKISDPFCLFYYNLKTNSMRSVTYEGLLHMATFKQALQFSVSYHYESLVSLET
What are the official names of this protein?
Putative F-box protein At3g47150.
Protein: RUXX_THESM
Sequence: MAERPLDVIHKSLDKEVLVILKRGAEYRGKLIGYDIHLNVVLADAQLIENGEPKKSYGKIVIRGDNVLAISPVEIE
What are the official names of this protein?
Putative snRNP Sm-like protein.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
Protein: SYC_CAUVC
Sequence: MTLKIHDTLTREKRDFVPADPQRVTMYVCGPTVYNYAHIGNFRPVVVFDVLFRVLRHLYGEDAVVYARNVTDVDDKINQKAADEGVPISVITDRYLAAYHQDADALGALRPTLEPKATEHIGAILEMIGQLVENGSAYAAEGHVLFDTQSFADYGQLSGRPLDEMIAGARVEVAPYKRHPADFVLWKPSKENEPEWESPWGAGRPGWHIECSAMIDKALGQTIDIHAGGIDLTFPHHENEVAQSRCAHKTSVLANYWMHNGFLDMSGEKMSKSLGNVIIPHELLETTPGEVIRWALLSAHYRQPLDWTPELLEQSKKSLDRLYGALRRAKDVAPDQAMEAPAEVMSALMDDLNTPLATSAFFEVSSAIEKAVTAGDTVAIAANKARLLEAGALLGFLQADPDAWFEGDASDELKAQVEDLLAKRVAARAAKDWSAADAIRGELDALGVVVMDGPAGATWRMKD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARC_BORBU
Sequence: MDIRTVLKDNFLQYSSYVIKDRAIASVVDGFKPVQRRIIHSLFEMHDGNFHKVANVVGNTMKYHPHGDTSIYEALVNIANKDLFIEKQGNFGNLFTGDPASASRYIECRLTPLAFDVLYSKEITIYESSYDGRNNEPLLYPAKIPVILIQGSEGIAVGMAAKILPHNFNEILNAVKSELLGESYDIYPDFPTGGIVDVNEYADGNGKVLVRAKIETIDEKTIVIRELPFGETTESLISSIEKAIRKNYIKVSSINDFTAENVAIELSLPRGVYASEVIEKLYHYTNCQISISVNLLLLSERYPVVYTIKDLIKFHAAHLQKILKMELELQKSKILEKIFYKTLEQIFIEKKIYKLLETISKEENILSIILSEVLRHKESFSREVLKEDVENLLKIPIRKISLFDIDKNSKDIKILNKELKSINSNISSIRGYSINFIDLLLAKYSKEHQRKTKISLIKSKNVKEIATKNMKVYLNLAEGFAGTSLFDGEFIGNASYYDKILVFRENSYVLKNIEDKTFIDKKNVCALVYDINNSKEQIFSIIYFNRLDNFYYVKRFKIDKFITDKVYEFLGENDEFVDFSLNPEFVEFSTNKDIVKRIEIDNFMVKSRSSIGKRISSNNLKKVKFK
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule (By similarity).
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS3A_AERPE
Sequence: MVRGGIRDTWRLKKWFKVVAPPLFGETVLGTTPADDPDKLIGRVMETTLFDITGDYSYVHVKMYFQVVRVEGDTAYTRFKGHELLRDYIRGLTRRKSSKVTGIFNVWTKDGYGLRVTAMAFTRQRCKTSQKSAIRKVMQEIVEQKARESTLDELIQLMVFSDHEGSLAYLIDESARKIYPLRKVEIAKSKLLWVPGPNGPEKAVVVSPLQLKVT
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: NEUPP_BOMMO
Sequence: MLLFSLTAITAVLAVSAVPTPSNNKDGSTISELPENWDQTKDDNRSLFLNKSDKNDLEPYPLALSEEGNQDGYDQTVDQRFDSPQSNGELDNLIMRPELYGEPPAMEGLASAFDLQRRKRGSGTKVGGAGAATKVVTKSGSGKKNLKPEDQAALSPIDLMTQHEAQRRKRGSGTKVGGAAASAKTATKNSGGNKKNFRPISERRKRDSGLSAADVRALLNLWEAQERRKQEYANQFAADRYYGRVNPDEEQPEVDENGDLWYNEPVVIGPHDRDYPHHSYFSEQNRMALARGYPDLYQVGPNELAQRYEEARRKRQYANKMKRFMVAKKRSDNMMHQNNYRPRDDLYTLAELLRSAPRVQEQDIPVYRRLIL
What are the official names of this protein?
Putative neuropeptide precursor protein, BmK5.
What are the subcellular locations of this protein?
Cytoplasm. Secreted.
Protein: AG1_XENLA
Sequence: MQAGLSLVCLVLLCSALGEAVLKKPKKQAGTTDTKTDQEPAPIKTKGLKTLDRGWGESIEWVQTYEEGLAKARENNKPLMVIHHLEDCPYSIALKKAFVADRMAQKLAQEDFIMLNLVHPVADENQSPDGHYVPRVIFIDPSLTVRSDLKGRYGNKMYAYDADDIPELITNMKKAKSFLKTEL
What is the function of this protein?
Does not appear to be required for cement gland formation.
What are the official names of this protein?
Anterior gradient protein 1, XAG-1, XAG.
What is the protein family that this protein belongs to?
Belongs to the AGR family.
What are the subcellular locations of this protein?
Secreted.
Protein: GET4_SCHPO
Sequence: MDAKIKRAEGRLREDPYEGHQMLRTLVNRQVKAKKHDDAVALLYSGAKTLFEIEQTGSAADLAIYMLDVYEKASYAASLDNKARALTLLGLFPAEEGARKQYVKRLLEWSKSAGPQGDKDVHFAVATMFVKWKEPASAEKHFVLGNEKSARAYGETMYYWFTSDSSISPDTFAGRPVLNYLLAENLISAWNSLETFTKHFTKSNAPDVENMSFDGKDFPVFKEYPQMNFLHLLIFTAYRKDKETYLSLVQKYPKKQDWEAALAKIEEIYFGIRPVSNQPNILANLMSSLFSGPPAATNQLDLE
What is the function of this protein?
May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane.
What are the official names of this protein?
Golgi to ER traffic protein 4.
What is the protein family that this protein belongs to?
Belongs to the GET4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSH2_YEAST
Sequence: MTKNVLMLHGLAQSGDYFASKTKGFRAEMEKLGYKLYYPTAPNEFPPADVPDFLGEVIADAPGDGENTGVLAWLENDPSTGGYFIPQTTIDYLHNYVLENGPFAGIVGFSQGAGVAGYLATDFNGLLGLTTEEQPPLEFFMAVSGFRFQPQQYQEQYDLHPISVPSLHVQGELDTITEPAKVQGLYNSCTEDSRTLLMHSGGHFVPNSRGFVRKVAQWLQQLT
What is the function of this protein?
Serine hydrolase of unknown specificity.
What are the official names of this protein?
Family of serine hydrolases 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMD9_PICGU
Sequence: MFRLLASSGQVSLRPVLLQHVRNNKHGLGFPNASGVPQSPSSMTSSSIVSPSQFTRSNSSAAGLSESPASSVDSKIENFLSKSAKDPLVREALDAETKNKLNYFKEQIDLAHRYRSIHDHDSERAFASTLDNLSRALEDESLRDTFVSRDLFSYAQVLNSGVYNNRTNRLSGAKNRDSDQYQNQNLHDEVLLKQAVLHLGELITNGEFKAILNAPTLSFLFYSMKQFQLYPEMIHLWENGVNDQQTGQVYLDEKILAVILPVTFEQNRFTYEEILHIYELNTEKLDKVGHELLTSMGKIAIAAGDYSRGLDSLESILQLYEKAQQSHYKNKILASLSDLHLSFIGTCKDIKISKHFFDKVVHYDLPYRVKLKVPHIQSLLENCYEQNEPMDNILYFWRASIAHYNTEQQLVLNSRYAILNNALFTIFFKKYPELNEESFSKLREIIAMYAESKPIDEVFLNTIIGNYSWDSKEVLEQIIENYDVYNVKRTPVSYRVCLKKTGSLESYSNEEILQKWNASLKHLDENKFTYIPVADWAALRDATILSHFKDARKEFYLSVLDKYKDYIQDHRSCIRFVRYWIKRKDVAADIARVASPEPQTFDCDIEIQVPQFRHLRKNINYVKEVQNMRFSG
What is the function of this protein?
Binds the 3'-UTR of mitochondrial mRNAs.  Involved in the processing or stability of mitochondrial mRNAs.
What are the official names of this protein?
RNA-binding protein RMD9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RMD9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PIFO_MOUSE
Sequence: MNTEEIPVAPPLRGVTPALQWKVNNYSFGTRQARKLFPHYHPPTWLGNLYLPLRGMPHTGPGCYAAATDWNGLAYNLSKVPTSTKGYAIGARTAVRFKPISKDVTPYPGMYQKVDTLSEKHKKSFAPFNILMPRFRSAAKGDSYPGPGTYNPEMKSVPKVTWPMKFGSPDWSQVPCLEKRTLKAELSADKDFRKHRSRVAYFSLYYQ
What is the function of this protein?
During primary cilia disassembly, involved in cilia disassembly.  Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome.  May act by stimulating AURKA activity at the basal body in a cell cycle-dependent manner.
What are the official names of this protein?
Protein pitchfork.
What are the subcellular locations of this protein?
[Isoform 1]: Golgi apparatus, Golgi stack. Golgi apparatus, trans-Golgi network. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasmic vesicle. Note=Accumulates specifically at the basal body and ciliary necklace during the early steps of cilia assembly and disassembly, when structural, functional and regulatory proteins are delivered to cilia. At S phase, accumulates in vesicles and declines during mitosis. In node pit cells, found close to the ciliary membrane along the axoneme. In spermatocytes, localizes to particles along the stabilized microtubules of tails.
Protein: UVRC_CLOBL
Sequence: MFDLEYQLKNLPDKPGVYLMKNNLGEIIYVGKAKILKNRVRQYFQKSQKHSEKVKAMVKNIEEFEYIITDSEIEALILECNLIKKYRPKYNILLKDDKHYPFIKVTLAEDFPRVVSTRKVTKDGSKYFGPYVDGSSVKDIIELIKKTFPIRTCKKNIVEGAKAIRPCLNYQIGLCKAPCAQYIKKSEYREIIDDVIKLLSGKHLDIVENFKLNMERAAENLEFEKAAMLRDKINIIEKIGEKQKIILNNFDNEDYISLYSDGKDTCFQVFFLRNGKIVGREHFIIEDTFDTNSSTLISNFLKEFYGGTAYIPKTIYVPNIEDEALLEQWLTLKKESKSTIKIPIKGEKKNILVLVEKNAKTTLENFKLKYLQEKALYDNVLKDLKNILRLQEEPIRIEAFDISNIQGFDSVGSMVVFEKGRAKPSDYRRFKINTVKGADDYKSMKEILTRRFQHGLSEIKSIQDRKLEFSSGKFSVFPDLILMDGGKGQINIALEVLNTFNIDIPVCGMVKDNKHRTRGLIYNGEEIIINKYGSVMKFITRVQDEVHRFAISYHRSLRGKNSFHSLLDDIPNIGEKRKKDLLFNFKSIDNIKKATYEELLSIPSMDKKSAECVLEFFK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.