PharMolix/UniProtQA huggingface dataset:
Protein: TAF7_CRIGR
Sequence: MSKSKDDAPHELESQFILRLPPEYASTVRRAVQSGHVNLKDRLTIELHPDGRHGIVRVDRVPLAAKLVDLPCVMESLKTIDKKTFYKTADICQMLVSTVDGDLYPPVEEPVAPADPKASKKKDKDKEKKFVWNHGITLPLKNVRKRRFRKTAKKKYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKETENQGLDISSPGMSGHRQGHDSLEHDELREIFNDLSSSSEDEEDVNVIDTEEDLERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKRQEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEGLESLLEK
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.  TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13.  TAF7 forms a promoter DNA binding subcomplex of TFIID, together with TAF1 and TAF2.  Part of a TFIID complex containing TAF10 (TFIID alpha) and a TFIID complex lacking TAF10 (TFIID beta).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 7.
What is the protein family that this protein belongs to?
Belongs to the TAF7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIPB_ECO24
Sequence: MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TU11_LOPAL
Sequence: CMTICTMEYWPVCGSDGKTYPNKCHLTSTACTSQKDITVLHEGKC
What is the function of this protein?
Acts as a neurotoxin by inhibiting an ion channel (By similarity).  May also act as a serine protease inhibitor, since it possess the kazal serine protease inhibitor signature.
What are the official names of this protein?
Turripeptide OL11-like.
What is the protein family that this protein belongs to?
Belongs to the conopeptide P-like superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SC6_SCHCO
Sequence: MVSRVLALISVAMLVGARPYVQNVGDVDLNDVDATVGTGVVDTGMSGDLLAGLLANGLLADLLSEDADGHIPEVTGSSTEEATSSSTWSGASSKPTDSAPTQCNSGTLQCCESTTEAKDIDRVLLSTLLGVDVGSITGLIGKNCSPVSVVGVGAGSTCSTQTVCCDGDSFDGLINLGCKSGNVAV
What are the official names of this protein?
Hydrophobin-6.
What is the protein family that this protein belongs to?
Belongs to the fungal hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: MEG10_DANRE
Sequence: MMSSCGPLLLAVSCCLVALTSSLNLDDPNVCSHWESYSVTVQETYAHPFDQIYYTSCTDILNWFKCTQHRVSYRTAYRRGEKTMHRRKSQCCPGFYESGDICVPHCAEKCVHGRCVAPNTCQCEPGWGGADCSSACDRDHWGPHCSSRCQCKNEALCNPITGACICAPGYHGWRCEDLCDHSTYGNNCQQKCLCQNNATCHHITGECVCSPGYTGAFCEDLCPPGKHGQQCEERCPCQNGGVCHHVTGECSCPAGWGMVCGQPCPTGRFGKNCSQECQCHNGGICSPSTGQCVCSSGYTGERCQDQCQVGTYGIGCSQACRCVNGAQCYHVSGACLCEQGYTGESCEERICPDGQYGLKCDRKCPCNTNNTRSCHPMSGECSCQSGWSGLYCNETCAPGFYGEACQEVCRCQNGADCHSVSGECICAPGYKGSDCAIACPPGTYGINCTSLCSCKNGAICSPIDGSCSCQAGWHGVDCSINCPSGTWGLGCNLSCVCGNGGACNALDGKCTCTPGWRGDRCDQHCQDGTYGLDCRERCDCSHADGCHPSTGHCRCLAGWTGIHCDSVCAEGRWGPNCSLSCNCKNSASCSPDEGACECAPGFRGTTCQHICSPGVFGHRCSQACPHCVHSNGPCHHVTGQCECLPGFKGALCNEVCPSGKFGKNCGGSCTCTNNGTCSPMDGSCQCYPGWIGSDCSQPCPPGQWGPNCIHTCNCHNGAFCSAYDGECKCTAGWTGLYCTQRCPLGFYGKDCVQACQCENGADCNHISGQCTCRTGFMGRHCETKCPAGSYGYGCRQVCDCLNNSTCDHMTGTCYCNPGWKGTRCDQAGGNIAESPNSLTSAALPMDSYQIGAITGIIILVLLVLILLLLFIIYRKKQKGKESSMPSVTYTPTMRANTDYAIAESLPQTEVLPNSNYFSNPSYHTLTQCSSPPHINNIPYGKMNNNQLFVNLKNTEPRKRLSLLDHTGTLPADWKQGGSFSELGAYGVDRRYMGKSLRDLVKSLPYHASSCSLNSSENPYATIKDPPLLLTKSTECGYVEMKSPAHRDSPYAEIHSSSPANKNVYEVEPTISSVQALTNNNCNGPFCQDPYDLPKNSHIPCHYDLLPTRDSSPSPTEDSK
What is the function of this protein?
Membrane receptor involved in phagocytosis by macrophages and astrocytes of apoptotic cells (By similarity).  Essential factor in the regulation of muscle development including myogenesis (PubMed:22371254, Ref. 4).  Likely plays a key role in muscle cell proliferation, adhesion and motility (PubMed:22371254, Ref. 4).  May control the balance between skeletal muscle satellite cells proliferation and differentiation through regulation of the notch signaling pathway (Ref. 4).
What are the official names of this protein?
Multiple epidermal growth factor-like domains protein 10, Multiple EGF-like domains protein 10.
What is the protein family that this protein belongs to?
Belongs to the MEGF family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: AOC1_RAT
Sequence: MCLAFGWAAVILVLQTVDTASAVRTPYDKARVFADLSPQEIKAVHSFLMNREELGLQPSKEPTLAKNSVFLIEMLLPKKKHVLKFLDEGRKGPNREARAVIFFGAQDYPNVTEFAVGPLPRPYYIRALSPRPGHHLSWSSRPISTAEYDLLYHTLKRATMPLHQFFLDTTGFSFLGCDDRCLTFTDVAPRGVASGQRRSWFIVQRYVEGYFLHPTGLEILLDHGSTDVQDWRVEQLWYNGKFYNNPEELARKYAVGEVDTVVLEDPLPNGTEKPPLFSSYKPRGEFHTPVNVAGPHVVQPSGPRYKLEGNTVLYGGWSFSYRLRSSSGLQIFNVLFGGERVAYEVSVQEAVALYGGHTPAGMQTKYIDVGWGLGSVTHELAPGIDCPETATFLDAFHYYDSDGPVHYPHALCLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGYVLVLRTTSTVYNYDYIWDFIFYSNGVMEAKMHATGYVHATFYTPEGLRHGTRLQTHLLGNIHTHLVHYRVDMDVAGTKNSFQTLTMKLENLTNPWSPSHSLVQPTLEQTQYSQEHQAAFRFGQTLPKYLLFSSPQKNCWGHRRSYRLQIHSMAEQVLPPGWQEERAVTWARYPLAVTKYRESERYSSSLYNQNDPWDPPVVFEEFLRNNENIEDEDLVAWVTVGFLHIPHSEDVPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPQDKGLNRVQRWIPEDRRCLVSPPFSYNGTYKPV
What is the function of this protein?
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis.
What are the official names of this protein?
Amiloride-sensitive amine oxidase [copper-containing], DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RS13_FRAP2
Sequence: MARIAGVNIPVHKHTVIGLTSIYGIGKTRAQQICQSCKVDPTVKIKDLSEEQIETLRTEVAKFTVEGDLRREVSMDIKRLMDLGCFRGRRHRRSLPVRGQRTKTNARTRKGPRKPIKA
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PURT_SYNE7
Sequence: MTFADRLPRRLMLLGSGELGKEFAIAAQRLGNTVIAVDRYAHAPAMQVADASAVISMLDGEALEAVVQEFQPDLIIPEIEAIRTEKLQEFEDRGLTVIPTARATHFTMNRDRIRDLAAQQLGLRTARYAYASCFEELQTVAAAIGYPNVIKPVMSSSGKGQSIIQQPDQLQAAWDYAIAGSRGDSQKVILEEFIPFELEITLLTIRQWQGPTLFCPPIGHRQERGDYQESWQPAPLRPDLLAQAQAIAAQVTEALGGAGLFGVEFFVTPDEVIFSELSPRPHDTGMVTLISQNLNEFELHLRAVLGLPIPAIELLGPSASRVILAEDSGDRPSYAGVAAALQEPWVDLRLFGKPDMRPQRRMGVALARDESVEAARAKADRAASQVTIQPS
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RL24_LISMH
Sequence: MHVKKGDKVKVITGKDKGKSGKVLAAFPKKDRVLIEGINMVKKHTKPSNVNPQGGILNVEAPIHVSNVMLIDPKTGEPTRVGYEVKGDKKVRVAKKSGEVIDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CTR86_ASHGO
Sequence: MAHPSEVAQLGLLAKSVNNESAEFTGLSDALEKLGPIVRNSSLDHNYRKELSEDRAIWKEICDCLNGAHLDRVEEKEPRHLRMRAVRGMILLGRNLSVENQRLPQELALHSRVVELLAQVQCQYDEMEIALHKAAYELLYNLTRASATFDQQSLGNVCRALRYPLGAHGSRDLALPVSLYFLNMVRDDEFLFAFLKHPDADKIVYQFMLQGVIKNHTELFDVIDNKTHDLENLSSLGAIQMSIWSCLVTHASFSPYLERLESHNWEAFDTILRFAQLVVTSSEKWDKEQLTAITVWAFRIFESTASSVEEYTRRGIDDEAEASRLHQKLLVVLDILSVFSKYESIRKFIMFYNGVEVLINTLRYLQNHCMRINFTKAKSNMAATFKAYNSNYERVEDEGKIKSIINIETSSIKSTNFPECKSLIIEILGFLTYKNREVQDKCRELHGLELVLSNCVIDDNDPFIKERSIMCIRFLLEDNAENQSFVAQLEAKKAVNDDVLAEAGYEVKVGADGKIGLTKNPRAAVEDKMDLNLT
What is the function of this protein?
Essential protein which may be involved in threonine biosynthesis.
What are the official names of this protein?
Copper transport protein 86.
What is the protein family that this protein belongs to?
Belongs to the CTR86 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THF1_PROM9
Sequence: MKAKLTVSDSKKLFHEEFPYVIPGLYKRIVDEILVELNLLNHQNEFKQDYLFCIGLTETFKELTKGYKPEKHLDLLFESLCISTNFEAKEIKEISKISQKEFSDKSSKDILKLLKEKSNSKLYPSRILNLGIYILISNSQDFKENNDIEKNKMISDIFEKLSLSRNKAEKDIGIYKSSISKMEQAKELIQEQRIKDKKKTL
What is the function of this protein?
May be involved in photosynthetic membrane biogenesis.
What are the official names of this protein?
Protein Thf1.
What is the protein family that this protein belongs to?
Belongs to the THF1 family.
Protein: RB11C_TOBAC
Sequence: MASGYGDASQKIDYVFKVVLIGDSAVGKTQILARFARNEFSLDSKATIGVEFQTRTLVIQHKSVKAQIWDTAGQERYRAVTSAYYRGAVGAMLVYDITKRQTFDHIPRWLEELRAHADRNIVIMLTGNKTDLEDQRAVPTEDAKEFAQKEGLFFLETSAMEATKLEDAFLTVLTEIFNIVNKKNLAADENQSNSNPASLTGKKILVPGPGQVIPGKKACCSS
What are the official names of this protein?
Ras-related protein Rab11C.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: LIPA_CAUVC
Sequence: MATVIDTLKARGSEDRAARHPEKQNRPDTPVLRKPEWLRVRAPGSGQYNETKGIVREHKLHTVCEEAACPNIGECWSQKHATMMIMGEICTRACAFCNVTTGLPTQLDPDEPRRVAEAVAKMGLKHVVITSVDRDDLLDGGARHFAEVVTSIRAAAPGTTIEILTPDFLRKDGAENVVIDSKPDVFNHNLETVPRLYLKIRPGARYYNSLRLLDRVKQRDPSQFTKSGLMVGLGETKEEVMQVMDDMRSAGVDFITIGQYLQPTRKHAAIDRFVTPEEFKAYEAIARAKGFLMVSSSPLTRSSHHAGEDFAKLQAARRALDARTA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCEH_ECO8A
Sequence: MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRESRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: 1002L_ASFM2
Sequence: MGNKESKYLEMCSDEAWLNIPNVFKCIFIRKLFYNKWLKYQEKKLEKRLRLLSFYHAKKDFIGIRDMLQTAPGGSYFITDNITEEFLMLVLKHPEDGSAEFTKLCLKGSCIMIDGYYYDNLDIFLAESPDLYKYPLIRYDR
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 100-2L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 100 family.
Protein: NS7A_BC279
Sequence: MKIILFLTLIALASSELYHYQECVRGTTVLLKEPCPSGTYEGNSPFHPLADNKFALTCISTHFAFACADGTRHTYQLRARSVSPKLFTRQEEVHQELYSPLFLIVAALVFIILCFTIKRKTE
What is the function of this protein?
Non-structural protein which is dispensable for virus replication in cell culture.
What are the official names of this protein?
Protein 7a, Accessory protein 7a.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass membrane protein.
Protein: LEA19_ORYSI
Sequence: MASHQDQASYRAGETKAHTEEKAGQVMGASKDKASEAKDRASEAAGHAAGKGQDTKEATKEKAQAAKERASETAQAAKDKTSGTAQAARDKAAESKDQTGGFLGEKTEQAKQKAAETAGAAKQKTAETAQYTKDSAIAGKDKTGSVLQQASEQVKSTVVGAKDAVMSTLGMTEDKAGTDDGANKDTSATAAATETTARDH
What is the function of this protein?
Involved in response to drought stress.
What are the official names of this protein?
Late embryogenesis abundant protein 19, OsLEA19, Late embryogenesis abundant protein, group 3, LEA-3, OsLEA3-1.
What is the protein family that this protein belongs to?
Belongs to the LEA type 4 family.
Protein: PLS3_RAT
Sequence: MAGYLPPKGYAPSPPPPYPVPAGYPEAAALHPGPGQAPVPTQGPAPAPGFSLFPSPGPVVPGPPGPFVPLPGVPSGLEFLVQIDQILIHQKAERVETFLGWETCNRYELRSGTGQQLGQAAEESNCCARLCCGARRPLRIRLADPGDREVLRLLRPLHCGCSCCPCGLQEMEVQAPPGTTIGHVLQTWHPFIPKFSILDADRQPVLRVVGPCCTCGCGTDTNFEVKTKDESRSVGRISKQWGGLLREALTDADDFGLQFPVDLDVRVKAVLLGATFLIDYMFFEKRGGAGPSAITS
What is the function of this protein?
Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of the phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer membrane of the mitochondria (PubMed:29171872).  Plays an important role in mitochondrial respiratory function, morphology, and apoptotic response (By similarity).  Mediates the translocation of cardiolipin from the mitochondrial inner membrane to outer membrane enhancing t-Bid induced cytochrome c release and apoptosis (By similarity).  Enhances TNFSF10-induced apoptosis by regulating the distribution of cardiolipin in the mitochondrial membrane resulting in increased release of apoptogenic factors and consequent amplification of the activity of caspases (By similarity).  Regulates cardiolipin de novo biosynthesis and its resynthesis (By similarity).
What are the official names of this protein?
Phospholipid scramblase 3, PL scramblase 3, Ca(2+)-dependent phospholipid scramblase 3.
What is the protein family that this protein belongs to?
Belongs to the phospholipid scramblase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass type II membrane protein. Nucleus. Note=Palmitoylation regulates its localization to the cell membrane or the nucleus; trafficking to the cell membrane is dependent upon palmitoylation whereas in the absence of palmitoylation, localizes to the nucleus.
Protein: PRM1_CANAL
Sequence: MFRNYLNLPEILTQVYLNKYAILLILILIKLILLETSILDNLNSVLLDNSICDNGEIQPVLNTVHYMIVDSLQTLEAAGIVSIILTLKVIKQLALFFIELFFGTYICLLNAALKGSTEVALDASEGVIRAVNATVVSATNDIESALKGLSSIINDLVTGFNAIKNMFTGSKSDPTQYQNKINITLGDLKSKIMIPSEVLTKLDNFKNSSLYGLSQLGNGTQTIVSTPFELAIKKLNTMKSSYNFTTGAPSPINFREECLKDMSKLKDVQTDLAKLVEKISKWLFIGLVLAMVGSILYVSYIQWRHWRRMDKFISETGIDKEVQFRNQYNIYNNFLIYTIVKRMGIELNERTIWMLSFMFSKISRNVFFFGIMGVVSVVAQYILLNSVQSSMNNHIKSFDITSNSTSMSASTIYLRDMNTYIDDTQDKLNQELFSGIKEISVSLNSTIVEFLDKLNETLSDIFGSTPLAGPINTVVYCTIGRKLEKVEKGLTWMNDNLNINIPSISRDIEDGLSHMTFLQPQSVLARANKIIDLYRKSILLELYISLGLLGVWLFQIFVGSATLTIRYWNSTRQGNNSYAISSPHELSEQEKQVYGYPLSHPLIDGKDLTTSSSFYPTTEEKSK
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein PRM1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIP13_CRIRI
Sequence: FPLPCAYKGTYC
What are the official names of this protein?
Riparin-1.3.
What are the subcellular locations of this protein?
Secreted.
Protein: RPPH_SULNB
Sequence: MQNKKSYRPNVAAVILSSKYPEKCEFFVAHRTDIRNAWQFPQGGIDEGETPEDALYRELLEEIGCNNVEILGEFPEWITYDFPKTARGKVYPFDGQTQKYFLVRLKEEAQINLQAFEIPEFKEYTFVKYDELFQKVTYFKRKVYRRVIDHFIKEGLI
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RPOE_STRP1
Sequence: MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQNYLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDGAQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDSELNEIIPEDDFEEVDINEEDEEDEEDEEPVL
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: AHBB_METBF
Sequence: MDKTDVKLLKLVQDGIPITHSPFKGFASELGISEQEVVDRLKNLQKAGKIRRFAASIGHRAIGITANAMCVWNVPDEQIETVGNIMAEFPEVTHCYERPRYPDWPYNLFTMVHSYTPEDCEKVAVRISEATGIRDYTLFFSEREFKKTGVRL
What is the function of this protein?
Involved in siroheme-dependent heme b biosynthesis.  Catalyzes the decarboxylation of siroheme into didecarboxysiroheme.
What are the official names of this protein?
Siroheme decarboxylase beta subunit, SH decarboxylase AhbAB.
What is the protein family that this protein belongs to?
Belongs to the Ahb/Nir family.
Protein: KITH_MACCJ
Sequence: MYEHYHSGWIECVTGSMFSGKSEELIRRVRRGLFAKQKVIVFKPSIDDRYSELEVVSHNGNKVEAVNVHHSSEILEHVKEAHDIIAIDEVQFFDNDIVGVATQLAEEGYRVIVAGLDMDFRGVPFEPVPELMAVSEHVTKLQAVCSVCGAPSSRTQRLIDGVPAKFDDPIILVGAKESYEPRCREHHVVPK
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_KLEP3
Sequence: MNRLFRLLPLASLVLTACSLHTPQGPGKSPDSPQWRQHQQAVRSLNQFQTRGAFAYLSDEQKVYARFFWQQTGQDRYRLLLTNPLGSTELSLTAQPGSVQLIDNKGQTYTATDAEEMIGRLTGMPIPLNSLRQWIIGLPGDATDYSLDDQYRLRELNYTQNGKTWHVTYGGYTSDTQPALPSNVELNNGAQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: EIF3G_XENTR
Sequence: MPTEDYDSKPSWADQVEEEGIDPEPISPPVTKVQQDPASFVLDTPQEVINGKIKTITEYKLNDEGKKIKIVRTFKIETLKASKVVAHRKNWKKFGNSEYDPPGPNVATTTVSDDVLMTFITSKEDLNNQEEEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGDKEKAPGAEPEPAQAPVSKTGKYVPPSLRDGGSRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Eukaryotic translation initiation factor 3 subunit 4.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPB_ECO27
Sequence: MTEAMKITLSPQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGIRKVEWPDLDDAQRQELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPELIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLASAAQENEPFWRLPLAEFHRNQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGWLHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTP1_MOUSE
Sequence: MEDIKDSKVKRFCSKNILIILGFTSILAVIALIAVGLTQNKPLPENVKYGIVLDAGSSHTNLYIYKWPAEKENDTGVVQQLEECQVKGPGISKYAQKTDEIGAYLAECMELSTELIPTSKHHQTPVYLGATAGMRLLRMESEQSADEVLAAVSTSLKSYPFDFQGAKIITGQEEGAYGWITINYLLGRFTQEQSWLSLISDSQKQETFGALDLGGASTQITFVPQNSTIESPENSLQFRLYGEDYTVYTHSFLCYGKDQALWQKLAKDIQVSSGGVLKDPCFNPGYEKVVNVSELYGTPCTKRFEKKLPFDQFRIQGTGDYEQCHQSILELFNNSHCPYSQCAFNGVFLPPLHGSFGAFSAFYFVMDFFKKVAKNSVISQEKMTEITKNFCSKSWEETKTSYPSVKEKYLSEYCFSGAYILSLLQGYNFTDSSWEQIHFMGKIKDSNAGWTLGYMLNLTNMIPAEQPLSPPLPHSTYIGLMVLFSLLLVAVAITGLFIYSKPSYFWKEAV
What is the function of this protein?
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.  Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP.  Hydrolyzes ATP and ADP equally well.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 1, NTPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPDase 1, Ecto-ATPase 1, Ecto-apyrase, Lymphoid cell activation antigen.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: STAC2_MOUSE
Sequence: MTEMSEKENEPDDAATHTPPGTVSTLQETKLQRFKRSLSLKTILRSKSVENFFLRSGSELKCPTEVLLTPPTPLPPPSPPPASTDRGLPTPTPSPCPVPRPLAPLKPVRLHSFQEHVFKRASPCELCHQLIVGNSKQGLRCKTCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLVHAPPPACAMNKESPPTGTSGKVDPVYETLRYGTSLALMNRSSFSSTSESPTRSLSERDELTEDGEGSIRSSEEGPGDSVFTAPAESEGSGPEEKSPGQQPPKLPLRKDVGPMYSYVALYKFLPQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCCQPFSGNKEQGYMSLKENQICVGVSRSKDSDGFIRVSSGKKRGLVPADSLAEI
What is the function of this protein?
Plays a redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity (PubMed:29467163).  Slows down the inactivation rate of the calcium channel CACNA1C (PubMed:25548159, PubMed:29363593).
What are the official names of this protein?
SH3 and cysteine-rich domain-containing protein 2, 24b2/STAC2, Src homology 3 and cysteine-rich domain-containing protein 2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with CACNA1C at the plasma membrane of transfected cells.