PharMolix/UniProtQA huggingface dataset:
Protein: PHNU_SALCH
Sequence: MSLILPLEKPALNLRPLLWLLLPLLVLATLFFWPLSLIVEQALRGANGEIGLETFRHVVDSKRFVGALLNTLQIAFFATAGCLLLGSAMSLILVFIPFPGSELIGRVVDTFIALPTFLITLAFTFIYGSAGLLNGTLMSLFAFELPPVDFLYSMQGVILAEITVFTPLVMRPLMAALRQIDKSQLEAASILGAHPLRVIGQVIFPAALPALMAGGSLCLLLTTNEFGIVLFIGAKGVNTLPMMVYSKAILESDYTVACMIALINIVLSLGLFSLYRLAASRTGVRS
What is the function of this protein?
Probably part of the PhnSTUV complex (TC 3. A. 1. 11. 5) involved in 2-aminoethylphosphonate import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Putative 2-aminoethylphosphonate transport system permease protein PhnU.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OAT_PLAF7
Sequence: MDFVKELKSSQDYMNNELTYGAHNYDPIPVVLKRGKGVFVYDIEDRRYYDFLSAYSSVNQGHCHPDILNAMINQAKKLTICSRAFFSDSLGVCERYLTNLFGYDKVLMMNTGAEASETAYKLCRKWGYEVKKIPENSAKIIVCNNNFSGRTLGCVSASTDKKCKNNFGPFVPNFLKVPYDDLEALEKELQDPNVCAFIVEPVQGEAGVIVPSDSYFPGVASLCKKYNVLFVADEVQTGLGRTGKLLCTHHYGVKPDVILLGKALSGGHYPISAILANDDVMLVLKPGEHGSTYGGNPLAAAICVEALKVLINEKLCENADKLGAPFLQNLKEQLKDSKVVREVRGKGLLCAIEFKNDLVNVWDICLKFKENGLITRSVHDKTVRLTPPLCITKEQLDECTEIIVKTVKFFDDNL
What is the function of this protein?
The enzyme has a very narrow substrate specificity and can only catalyze the transamination of alpha-ketoglutarate with ornithine or N-acetylornithine and, to a lesser extent, of glutamate-5-semialdehyde with glutamate and alanine.
What are the official names of this protein?
Ornithine aminotransferase, PfOAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLPM1_RAT
Sequence: MYPNWGRYGGSSHYPPPPVPPPPPPVALPEASPGPGYSSSTAPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMIHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPSSAQPYLPPAQPSPSKPQLPPPPPSIPSGNKTTIQQEPLETGAKNKNAEQKQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGLVTAKDVPEPIKEEAPVPATSQIAEPLAAEEPPLPPPNEEMPPPLPPEEPQNNSSEMSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQRHTQLQQILQQYQQVIQHSPHIQTMSLDVQLRHYEMQQQQFQRLYQEWEREFQLWEEQLHSYPHKDQLEEYEKQWKSWQGHMRATQTYLQEKVTSFQAVKNQYMGNMAMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPSTIPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAVLPPPSLSSAGPPPVLPPPSLSGAPPVLPLPPLSSATPPPGIPPPGVPQGMPPQLTAPVPPASSSQNSQVPEKPRQALLPTPVSFGSTPPSPYHPPPQSEQGNSKPLNKVFSSEQGLGESSSALSQSVIAAKDTPVKSGGLLADPPKGSFLEGPRGPREQKEQLQKLKDFGSEPQTADHLPPPDSRLQNTSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSCVPMTRPPVPIPPPPPPPPPPPPPPPVIKPKTSSVKQERWDEDSFFGLWDTNDDQGLNSEFKRDTAAIPSAPVLPPPPVHPSIPPPGPMPMGMPPMSKPPPVQHTVDYGHGRDMPTNKVEQIPYGERITLRPDPLPERSAFDADHAGQRDRYDRDRDREPYFDRQSNMTDHRDFKRDRETHRDRDRVLDYERDRFDRERRPRDDRNQSYRDKKDHSSSRRGGFDRPSYDRKSDRPPYEGPPMFGGERRTYPEERMPLPAPSLGHQPPPVPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFIAEVEKEEKDPDSGKKVKKKVMEYEYEADMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEINKMAEHWEAAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEDQKEEKKDAEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYETRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAERALNRTKYI
What is the function of this protein?
Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation.
What are the official names of this protein?
YLP motif-containing protein 1, Nuclear protein ZAP3.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Migrates to nucleolar caps upon blockage of transcription.
Protein: ZW10_CAEEL
Sequence: MASSEGSYRDLEKKLKNGLTSISQDIVDKYGNLKVSLNVNATAKLIFDRLENLEDIAEMSTRNLSNLIDQTAKDSPEMLAEIKSQAQSCENLVEFLQSMKNVEEQLIIMRSKTTNRVEWGTAILACKDFLNDTNMLLEGIGRDGFDMSVPLKHFAAEYSVLSYNCRYQLSADYERAMNVPKLSKQKCGDRTNVSFSVFNVGSVEDQKMLNETLSAMNMIGQLPERLDAWKIVILNVFCEAIVASRDGVDVYIVDNPTPDQTRFLINQKPRGKKDKTIDVAKVLESMEVFFTKLHSVLHSHELLDATGKTFTSMIGSVIEEQLITMILKDVIAIAAPVTETADEDQEMFINLLQIGEVFVERMKELGFFSQKAKLLFTLDTDTIFVTRRCFAIVSKANKLINETYDKLVTVGVDDSAIKDIDLLAKAHTHAEHFAKEYGKDLGRLWSHNEDSQFPSFFAFQKCTVSESTINFVNLLRDNVKAAFACEDEGARAKLALTAENIVRLYVILTPRKHAELFSSIPNMAAIFYNNCHYISHCIMTMSFEASGDNQKTLLEPLLLDSVIRLRTVAADCMEKTLTRCRREMTAYLEDHSIFEHLPASYKTTKNTFAAAEEMSESADILVPREEPKIIKCLAACLLHIRLIAKNLREPLTEVVYCKVIGSLVSFLLDSLVRHVVTTSDFRENDANVMADVFKRLLEVVANIVAYKEQTKVTDFCAREYFRLNEIVFVLGNRMQDIEHRWFNAKGPMAEHLSRSEVVGLIKALFADSQHRSDLIARL
What is the function of this protein?
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis (PubMed:9298984).  Required for the assembly of the dynein-dynactin and mdf-1-mdf-2 complexes onto kinetochores (PubMed:18936247).  Its function related to the spindle assembly machinery and kinetochore-microtubule attachments likely depends on its association in the mitotic RZZ complex (PubMed:18936247).  The RZZ complex recruits the spindly-like protein spdl-1 to kinetochores (PubMed:18765790, PubMed:18936247).  To prevent irregular chromosome segregation, the complex also inhibits the attachment of the kinetochore-associated NDC80 complex to microtubules (PubMed:24231804).  The recruitment of spdl-1 to kinetochores relieves this inhibition (PubMed:24231804).  Required for embryonic development (PubMed:9298984).
What are the official names of this protein?
Centromere/kinetochore protein zw10 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZW10 family.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the kinetochore during nuclear envelope breakdown and remains there until the metaphase-anaphase transition. Localization of the RZZ complex to kinetochores is dependent upon knl-1.
Protein: RNPH_ALISL
Sequence: MRPSGRTAQQVRPITITRHFTAHAEGSVLVEFGNTKVICTASVEENVPRWLKGKGKGWVTAEYGMLPRATHTRNNREAASGKQGGRTMEIQRLIARSLRAAVDLEALGEQMITVDCDVIQADGGTRTASITGASVALADAINHMIASGKLKKNPMKGHVAAVSVGIYKGEAICDLEYLEDSAADTDMNVVMMEDGKMIEVQGTAEVAPFSHQELLDMLALAQQGINDIIEKQKAALAE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: SSRP_STREM
Sequence: MAKGEGNVLAQHKKARHDYHIVETIEAGIVLTGTEIKSVRAARIQLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTGMTLVPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PGK_KLULA
Sequence: MSLSSKLTVKDLDVTGKRVFIRVDFNVPLDGKKITSNQRIVAALPTIQYVLEKKPKAIVLASHLGRPNGEVNDKYSLAPVADELSRLLQKPVTFLHDCVGEEVTNAVNNAKDGEVFLLENLRFHIEEEGSRKVDGNKVKADKAAVTKFREQLSSLADVYVNDAFGTAHRAHSSIVGFDLPNRAAGFLLSKELQYFAKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSLIIGGGMAFTFKKVLENTEIGDSIYDAAGAELVPKLVEKAKKNNVKIVLPTDFVIGDKFSADANTKVVTDKEGIPSGWQGLDNGPESRKAFAATVAEAKTIVWNGPPGVFEFAPFAKGTEALLDAVVASSQAGNTVIIGGGDTATVAKKYGVVDKISHVSTGGGASLELLEGKELPGVTFLSNKQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_PSET1
Sequence: MDTHRPIRRALLSVSDKTGIVEFARALEAQGVDILSTGGTCKLLADNGIKVTEVSDHTGHPEIMDGRVKTLHPKIHGGILARRGQDESVMAENNISAIDIVVVNLYPFANTVAQENCSLEDAIENIDIGGPTMVRAAAKNHKDVTIVVNASDYDRVISEMQSNKGSTTYKTRFDLAIAAYEHTAQYDGMIANYFGKMVPDYTEEAAEDTKFPRTINMQFTKKQDMRYGENSHQDAAFYVENDIVEASVATATQLQGKALSFNNIADTDAALECVKEFDVPACVIVKHANPCGVSIGSNILEAYERAFKTDPTSAFGGIIAFNQELDAATAEAIVERQFVEVIIAPSVSDAAAKIVSAKQNVRLLVCGQWTDKAAGQDIKRVNGGILVQDRDLGMVTQGDLKVVSKRQPTEQELKDLLFCWKVAKFVKSNAIVYARDGMTIGVGAGQMSRVYSAKIAGIKAADENLEVKGSVMASDAFFPFRDGIDAAAAAGITAVIQPGGSMRDAEVIAAADEAGMAMVLTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RIMM_MARMM
Sequence: MTEPADDLVFIAAIAGAHGVRGECKVKSFAGNPADAFKYGAFLDIDGKTILTPKAARPVKDGFVVRFAEPLDRDKAQALKGTKLHVLRSALPELEEDEFYHSDLLGLKVQGLDGAPMGTLKAVHNFGSGDLLEITGTPDRNGSWMLPFTREFVPHVSIAEGVITIDPPEDVGSKAEEEGGGAPDD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y308_METJA
Sequence: MDVNEIRENAKKLMELMMLDKPFVAVKLAKSKEEIPEGYETLDEEKRHCEMIQMARLERKKLYATVDKHLCKGGAYAMGVFRNPPEPLATGKLYVKLGNFKDEEAAKKTVDAIPKVEEEIYATVYAPLDETDFIPDSIVFIGEPLYALRLVQAILYHKGGRFQADFSGIQSLCADAVAAVYTRKAPNMTLGCNGSRKYAGIKPEEVVVAFPPEKLKDIVEAIEHFRQVWTCGH
What are the official names of this protein?
Uncharacterized protein MJ0308.
Protein: YP016_YEAST
Sequence: MLLFQILCRIASCNYTIRPTRDEASFNYAILNIALHTVKEKICTKEYGFKSLINKNFPKIFVWPSEKTGNAHPLGFRPECLYYYIK
What are the official names of this protein?
Putative uncharacterized protein YPR016W-A.
Protein: RS14_PSYA2
Sequence: MAKKSMINRELKREKMVAKYADKRIKLKETISDMTASDETRMEAMLELQALPRNASPVRLRNRCAITGRPHGYFRKFGLSRNMLRERVMQGDVPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RL11_LEICH
Sequence: MVAESKAANPMREIVVKKLCINICVGESGDRLTRASKVLEQLCEQTPVLSRARLTVRTFGIRRNEKIAVHCTVRGKKAEELLEKGLKVKEFELKSYNFSDTGSFGFGIDEHIDLGIKYDPSTGIYGMDFYVVLGRRGERVAHRKRKCSRVGHSHHVTKEEAMKWFEKVHDGIIFQAKKKKKMIRRRRR
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GBB_SCHPO
Sequence: MDSGSRVNVNIQGTRVLKNKLGKIPDIDISTDGKYLLSASTNDVLLVWDLHTSNKVAFFEAPSVWIMTCAFSPSTKSIAAGGLNNFCVVYDTSVPDADPVELVGHAGFVSCCKYVDDGHLLTGSGDKTCMFWDIEQAKAISVLKGHEMDIVSLDFLPSNPNLFVTGGCDKLAKLWDLRAAYCCATFPGNTSDINSISFFPSNADFVTGAEDGIARCFDIRASAEIFQYSSPSSSPINSVLFSKSGKLLFIAKDKTCEVWDSISSKTITSLTGHENRISSLALTSDGTMLATGSWDECVRLWSSSG
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.  Required for adenylate cyclase activation.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TCPD_VIBCH
Sequence: MVNVIMKISSLKKGSNFSINIKNIKLDKKLLVAIIFLVLSILGGGAYLYYENEKTKKLEQARLQKIQKENSDKQTYLSDFKSAFEGLDYQALTGFYDVLRSDIDFFRVNNWLLDVMDCNVNCNLAFKRGSFDTFTYLEMNRNGAVIKPQFDQNKLQFANVDYISGFRSIYLKDLTEQERDKSENIIEQCSTKLSELYNLQLLMKEQVKFKINLPRNVTSISGYDWVKNSDIKFGSIEIENMPEKNLGLMKNIMNNSMMITSISLQNSSFKSKLNYYCY
What is the function of this protein?
Involved in TCP pilus biogenesis.
What are the official names of this protein?
Toxin coregulated pilus biosynthesis protein D, TCP pilus biosynthesis protein TcpD.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: C2D2B_HUMAN
Sequence: MKKSQREDIFKKMSEEMDNITAEEIIDKHLQKDLDAEENQNVAKTLRGKVREKLKISKINKGEKSSTEQLIDSEIHQRSKLSPQTEVSLDESLSFFILSGEEGSALGKSSEQRPVNRSYPKCFSLGVNLQNVAESEEEEFMKEFILTDILKVKAADYEDDQEQIKKQKANIFVPSSSPVVNQRKLPKDMMPRILEDEGFYIQRKPEIYKKTCNKMENRLLKLEEGKCWFGESGEIMSLPTPIKQSWNFRLNVRKEPLNPLLKTIYRKAVKYDLGSSFMNKMEGSREIYQLDLNIVGLQFSHHHLFNQEQVLCARLLQLYECFQDRQQQNVSQLLYEKLKALTDATKLSNENSEINQLTRKSLQDYYWQISNTKQMYDLERGKDLSLLHSILRTWKQIKSLRHGQGFTSTPIKLQVQRIKMNKCDEQEQISEMSETEKKNEGKELKNGKKLESLSYLASDETEIERIKPITLRPQLSFTAELTSLSKCSLHEQKRRAKIQKLKYFIKIFYNNKQVSCTSVSPLQFDFKVMFQQIFNIQLMYWPEVICLEVYEKSKRTSLLAKLYIPLPNYTELKGKTALQYVEFSSDKLVMPADGEVGSNVPFLLEGNGTEELCLLTSGKLSYSLSWSLDENGLPLIPMPQSLRSSYCSMLRNVDARSVPGIPWLMNEQKLFEWANEVRIDPNNPEYSDLMESVTYMRLKGQDIPKYFRLEQLQDEFNFVSEEEMAKSKRFQLLQLRNAGQLDNFLLQQMPLHDTEIPDLVFQEYESQKEKEVSVSDVNSITAQRINSANFLKKVRRLIMKRIVKISKCNLSDIVNDYEEIVSTSQLTDAVCKFVEPRRKLKPQRKERKKVTAQAISDGDIKILVRIVRAYNIPTRKTTINGSLDMPTCLKSSISCLRHRETIKSVASDETLHEDTVHPFVEVSFQHTVYKTNTASGSHPCWNEEIKVDFVSPGHDYSFSSLSKIKDNIYINIFDEMMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEISGTFQVTIPPVLLGYTWSNTYVFPKEDSNEQNLKECTFLNIFATIEPQISYVTCNPTLDKFLDQTEVLQRAQIFKKNCKAMFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVPNTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYVVTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKESFWKQLLPKNVQGTKIQSIQPEEIIYFETDKSMVEDLRNRIERTLKSKVMEWRPKHPTHWNRQCTFILRQILPKLEFGIGSFVSSEGDNEFERILQFYWVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYLASLVQHQ
What are the official names of this protein?
Protein CC2D2B.
Protein: Y2091_PHOV8
Sequence: MIAKPEREQIIALINREVVPAIGCTEPIAVALCVAKATETLGKRPERIKALLSANILKNAMGVGIPGTGMIGLPIAIALGALIGKSEYQLEVLKDSTPDAVAEGKKLIDSQAISIGLKENIEEKLYIEIICEADGDTATAIIACGHTNFIYVALNNQVLLNKQTTSTCNEDAKEPELNLRKVYDFATTTPLDEIRFILETKRLNKAAAERSFKGNYGHELGKILKSSKSEEQILGSNTFTHILSYTSAACDARMAGAMIPVMSNSGSGNQGITATLPVVVYAEDNHKSEEELIRALTLSHLTAIYIKQSLGRLSALCGCVVAATGSSCGITYLMGGTYEQITFAVQNMIANLTGMICDGAKPSCALKLSSGVSTAVFSAILAMEHKCVSSVEGIIDNDVDRSIRNLTRIGSQGMNETDKLVLDIMTHKQCD
What are the official names of this protein?
UPF0597 protein BVU_2091.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: BIR1_SCHPO
Sequence: MKPITSSSKRRWNRFRREMCNYSKRLDTFQKKKWPRAKPTPETLATVGFYYNPISESNSEERLDNVTCYMCTKSFYDWEDDDDPLKEHITHSPSCPWAYILSSKNNPNQNPQAAALTKCREQTFVDKVWPYTNRPDYHCEPSVMAASGFVYNPTADAKDAAHCLYCDINLHDWEPDDDPYTEHKRRRADCVFFTWKDPNSLSPTKLSFLSTSNIDPEDLTEDNSILPVSPTRDSTKSHKTLNFSPSRKNNLNARPLTMSLYTNTSEEKDSQPTRAPQSPTKPVLLTAPRRKNKSPKKSKPAVFKPVKPIFSDEDEDDDDLTASQPFSKGICNDSMQVAKKNFTEEIPLKEDEKDNELEHLVSPATSVHTTVSDITGHQSVTDESDEQNNCMSTPPKIEIESKIEEEISVVSKSKEISSSVSSVGKEQNHTEKQVAIETPEQQKVEKEDEHLNLQGSFIEESTKQPISSKPSTSSPDMTDAATGGRVSSSSFRDKILQTNFSPRSTIDSFSNISKKRNSEEANDENDETNLKIPIPEKKRKFQEVLQSKNILVSSTEDSHEPVKVTEDSQTAIHVSKFEDLENKSMESEQSLQLLSESENDDKPLIDLIPLLAIKRKDNLVSGVLEKGKSTSTSKTKFDTSIVDFIEKPKTEISEVLPEEKRKAICDESQTVRVSIDRGVTKTRDVSSPVSDEKSENVNHEEANSGHTVMNVHSSLDPQPIVQPNELESGSYLKDLPDRNVGNSEKVTFQEDDINSPKLQSKNNQTVEAVNTETSDKLQEKEANHELENIEKIEEKLTEVDKVSLSDAFPDQEIKNSRTSVQNGTRSVSKNTPEKETKVDKIDNVSKKDVETSPGSCETSSAFAKTYAEKEVTSINLPSVRKPLDESYYDHSISPFDPLCQSSFLAPQTPVKSKHALPLVEANAPPWEPIDFSSLLESPVPNPVEPNKLSEKELDMTVEQWIKFMYAKCAKEFEEACEEKIEWLLEEGKRAEEYIQNL
What is the function of this protein?
Seems to act in the pleiotropic control of cell division.  Has a role in chromosome segregation by recruiting condensin and ark1 kinase to appropriate sites as the cell progresses through mitosis.  Ark1 activity depends upon bir1 function and phosphorylation.  Ark1 with bir1 function is required for full-scale association with kinetochores and formation of a complex with mad3.
What are the official names of this protein?
Protein bir1, Chromosome segregation protein cut17.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere. Note=Interacts with the outer centromeric regions of the chromosomes during interphase. After chromatid separation moves to the middle of the spindle.
Protein: CYSD_ECO8A
Sequence: MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RL5_ACIC5
Sequence: MAARLKEKFIKEIRPALQKELGLENTMAVPRIEKIVLNMGLGEATQNSKLLDPLVADLAAIAGQKPVTTRAKKSIAAFKVREGMPIGAMVTLRGDTMYEFLDRLISVGLPRVRDFRGVSTKSFDGRGNYTLGVRDQLIFPEIDISKVEKLKGMNITIVTTAQDDNSARALLKQFGVPFRQTA
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: V127_FOWPV
Sequence: MGGGLVLPTRDPPKEQDTSETATNIPKLLKSIPGVKLGQQIRIGYKPGPETAKAFPEFDIKEVSNGLYELSRKSYLGDTKTCCINPSLSYYWEDSKNKIFDEYATGRSLKTCDPLTKTISGSTLCDNILTSLCLDEKSGVDRTMCNEWMGYALNRPDLSIPKSINDRYTKLCSKGANNIVCEDWLHHLRIIGGKENDEVIDNVLMQQTPEFKEKYMKCSFPSHNTVFLAYRVIEPRECWDQECITSNVHFLLSKNYHNLTLCHIYRCNISINNLLIDGKSSVKISCHDENISNKDKPKARNKAKFIDDILGSSFNINFGFFFVIFIMIALILIVLL
What are the official names of this protein?
Protein FPV127.
What is the protein family that this protein belongs to?
Belongs to the poxviruses A16/G9/J5 family.
Protein: MFNA_METAC
Sequence: MNEQGLSEKEIFSYLENAKSEDTDYYRVLSSMCTHPHKIAVEANRLFIEANLGDLGLFAGASRLEQEVVGMLGELLHAPSIDVPFGGSCESSACGYLTTGGTESNIQAVRGMKNLVTTGKKELKGAPNIVIPESAHFSFDKVADMMGIEVRRASLDSEFRVDMASIESLIDANTIGLIGIAGNTEFGQIDPIDKLSEIALENELFLHIDAAFGGFVIPFLEKPQPFDFKLPGVTSIAVDPHKMGLSTIPSGALLFRSASFLDSLKVNTPYLTTKAQFTLTGTRSGASAAATCAVMKYLGNEGYRKNVQYCMQLTEKLVIEARKIGFEPLLEPVMNVVALKVPNPDFVREQMLERFGWNVSITRTPRALRLVLMPHNTLEDIEIFVQDLKEVTVEI
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis.  Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Probable L-tyrosine/L-aspartate decarboxylase, TDC/ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: MBL2_CALJA
Sequence: MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQGPPGKLGPPGNPGPSGSPGAKGQKGDPGASPDCDSSLANPERKTLQTEINRIKKWVTFSLGKQVGKKLFLTNGETMTFDKVKALCAQFQASVATPMNQAENRALQSLVKEEAFLGITDEETEGQFVDLTGRRLTYTNWNKGEPNNADSREDCVVLLRSGGWNDVPCSSSHLVICEFPV
What is the function of this protein?
Calcium-dependent lectin involved in innate immune defense.  Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway.  Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
What are the official names of this protein?
Mannose-binding protein C, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH_DINSH
Sequence: MPELFAYTDGACSGNPGPGGWGALLIARDGDTVVKERALKGGEAETTNNRMELLAAIHALEALERPARLTVVTDSAYVKGGVTGWIHGWKRNGWKTSTKKPVKNEDLWRRLDAAQARHEVQWEWVKGHAGHPENERADALAREGMAPFKPGKSKAGR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_SULAA
Sequence: MEIEEIKVQTEVNGAPFIIETGYFAKQANGAVIVRQGDTAVLVAAVMSEEPQADIDFLPLTVEYREKYYAYGKIPGGFVKREGKPTDREILVARNIDRPIRPLFPKGFYNDIVITAYTLSADDKYDPDVLGIVGASAALHISDIPFEGPIAGVRVCRVNGEFIVNPTYQQKAQADIEIVVAGSKDAIVMVEGGAKEVPEEDILEAMMFGHQEIKKLIELQEELRLKCGKEKIQVAIDEEEIILKDKLKEFSYEKIKEAFKITDKKQRNKTINAIFEEAFKTLEIPEEKIKKASFIYKDIVSNVMRDNILNEGIRIDGRKPEEIRPIWIKVGVFPRNHGSAIFTRGQTQAFVTVTLGSLSEGQIEESIEAGEVMKRFMLHYNFPPFSTGEAKPPRATSRREIGHGNLAERALEPLIPPEEEFPYAIRVVSDILESNGSTSMATVCGGSLALFDAGVPMKKHVAGIAMGLIKAEDKFVILSDILGDEDHLGDMDFKVAGTRDGVTSIQMDIKVKGLTKEILEKALQQARDGRNYILDLMYQAIPEPRKEVSPYAPTVTTLRVLPDKIPIIIGPAGKNIKKIIEETKVKIDLDPEGLVKIYATSKEAAEKAVSMINELILDVEVGEVYMGKVTRVEDYGAFVELLPGRLSLLHVSQITGERLKSAKEKIKVGDVLKVKVSEIDDQGRIKVSLKDVPENVEPKNKFLFKEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.