PharMolix/UniProtQA huggingface dataset:
Protein: NUOG_PSEFL
Sequence: MATIHVDGKELEVDGADNLLQACLSLGLDIPYFCWHPALGSVGACRQCAVKQYTDENDKRGRIVMSCMTPATDGSWISIDDEEAKVFRASVVEWLMTNHPHDCPVCEEGGHCHLQDMTVMTGHNERRYRFTKRTHQNQDLGPFISHEMNRCIACYRCVRFYKDYAGGTDLGVFGAHDNVYFGRVEDGTLESEFSGNLTEVCPTGVFTDKTHSERYNRKWDMQFSPSICHGCSSGCNISPGERYGELRRIENRFNGSVNQYFLCDRGRFGYGYVNRKDRPRQPLLANGAKLSLDQALDKAAELLRGRNIVGIGSPRASLESNYALRELVGAEHFYSGIEAGELERIRLVLQVLKDSPLPVPNMRDIEDHDAVFVLGEDLTQTAARMALALRQSVKGKAEDMADAMRVQPWLDAAVKNIGQHALNPLFIASLAETKLDDVAEECVHAAPDDLARIGFAVAHALDASAPAVDGLDSEAAALAQRIADALLAAKRPLIIAGTSLGSKALIEAAANIAKALKLREKNGSISLIVPEANSLGLAMLGGESVDAALQAVIDGSADAIVVLENDLYTRTDKAKVDAALNAAKVLIVADHQKTATTDRAHLVLPAASFAEGDGTLVSQEGRAQRFFQVFDPQYLDASILVHEGWRWLHALRATLLDQPIDWTQLDHVTAAVASSSPQLAAIVDAAPSASFRIKGLKLAREPLRYSGRTAMRADISVHEPRTSQDNDTAFSFSMEGYSGSTEPRSQVPFAWSPGWNSPQAWNKFQDEVGGHLRAGDPGTRLIESQGDHLSWFASVPRAFNPAPGTWQVVPFHHLFGSEENSSKAAPVQERIPAAYVSLAKSEADRLGVNDGALLSLNVAGQTLRLPLRINEELGAGLVALPAGLAGIPPAIFGKTVDGLQEAAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).  Required for plants roots colonization.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit G, NADH dehydrogenase I subunit G, NDH-1 subunit G.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
Protein: MBNL2_MOUSE
Sequence: MALNVAPVRDTKWLTLEVCRQYQRGTCSRSDEECKFAHPPKSCQVENGRVIACFDSLKGRCSRENCKYLHPPTHLKTQLEINGRNNLIQQKTAAAMLAQQMQFMFPGTPLHPVPTFPVGPTIGTNAAISFAPYLAPVTPGVGLVPTEVLPTTPVIVPGSPPVTVPGSTATQKLLRTDKLEVCREFQRGNCARGETDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCMREKCKYFHPPAHLQAKIKAAQHQANQAAVAAQAAAAAATVMTQSTAKALKRPLEATVDLAFPPGALHPLPKRQALEKSNGASTVFNPSVLHYQQALTSAQLQQHTAFIPTVPMMHSATSATVSAATTPATSVPFAATATANQIILK
What is the function of this protein?
Mediates pre-mRNA alternative splicing regulation.  Acts either as activator or repressor of splicing on specific pre-mRNA targets.  Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle.  Antagonizes the alternative splicing activity pattern of CELF proteins.  RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3.  Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs.  Seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm at adhesion plaques.  May play a role in myotonic dystrophy pathophysiology (DM) (By similarity).
What are the official names of this protein?
Muscleblind-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the muscleblind family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Greater concentration in the nucleus. Expressed in or near large cytoplasmic adhesion plaques. Location in the cytoplasm is microtubule-dependent.
Protein: PSIE_ECO7I
Sequence: MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLADVLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLIIVDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRF_VIBCM
Sequence: MNDPKVIVALDYDNLADALAFVDKIDPSTCRLKVGKEMFTLFGPDFVRELHKRGFSVFLDLKFHDIPNTCSKAVKAAAELGVWMVNVHASGGERMMAASREILEPYGKERPLLIGVTVLTSMESADLQGIGILSAPQDHVLRLATLTKNAGLDGVVCSAQEASLLKQHLGREFKLVTPGIRPAGSEQGDQRRIMTPAQAIASGSDYLVIGRPITQAAHPEVVLEEINSSLV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RBSA_SHISS
Sequence: MEALLQLKGIDKAFPGVKALSGAALNVYPGRVIALVGENGAGKSTMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFLGREFVNRFGKIDWKTMYAEADKLLAKLNLCFKSDKLVGDLSIGDQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQFIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGAQPRTSGYVTLDGHEVVTRSPQDGLANGIVYISEDRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIILVSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HXC12_MOUSE
Sequence: MGEHNLLNPGFVGPLVNIHTGDTFYFPNFRASGAQLPGLPSLSYPRRDNVCSLPWPSAEPCNGYPQPYLGSPVSLNPPFGRTCELARVEDSKGYYREPCAEGGGGGLKREERGREPGAGPGAALLQLEPSGPPALGFKYDYTASGGGGDGSTGPPHDPPSCQSLESDSSSSLLNEGNKSASAGDPGSLVSPLNPGGGLSASGAPWYPIHSRSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLLLREQALSFF
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C12, Homeobox protein Hox-3.8.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COX6A_THUOB
Sequence: KEQPEFVPY
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6A, mitochondrial, Cytochrome c oxidase polypeptide VIa.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: HIS4_ECOSE
Sequence: MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSQDMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTGVRGVIVGRALLEGKFTVKEAIACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_SHIBS
Sequence: MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPL_CARHZ
Sequence: MDFTMSLVAGLIAIGAGIAVGFGAIGSGIGQGIAAGKAFEAMARQPEVRGTVQTFLIIALAFMETLTIYGLVIAFMLLNKMS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_STACT
Sequence: MSQEKKVFKTEWANRPLSIETGQMAKQANGAVLVRYGDTVVLSTATASKEPRDGDFFPLMVNYEEKMYAAGKIPGGFKKREGRPADEATLTARLIDRPIRPLFPKGYRHDVQIINMVLSADPDCSPEMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGEYVINPTVEQKEVSRLDLEVAGHRDAVNMVEAGASEITEKEMLDAIFFGHEEIKRLVDFQQEIIDYLQPEKTEFIPKERNAEVEEKVTALTEEKGLKDAIQTFDKKEREENIDAIRDEVVAEFEDEENPDNDEVIAEVNSILNDLVKEEVRRQIADEKVRPDGRKPDEIRPLDSEVGLLPRAHGSGLFTRGQTQALSVLTLGAMSEYQLIDGLGTEEEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERALRYIIPDTKDFPYTVRIVSEVLESNGSSSQASICGSTLALMDAGVPIKAPVAGIAMGLVTRDDNYTILTDIQGMEDALGDMDFKVAGTEKGITAIQMDIKIDGLTREIIEEALEQARVGRLTILNHMLETIDQPRPELSAYAPKVETMTIKPEKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAVDQDMINRAREIIEDITREAEVGQVYNAKVRRIEKYGTFVELFPGKDALLHISQIANQRINKVEDVLKLGDTIEVKVTEIDDKGRVNASHRALLNKED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEPA_ECO7I
Sequence: MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSRQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVPALWKPEIFSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LDH_FUSNN
Sequence: MLQTRKVGIVGIGHVGSHCALSMLLQGVCDEMVLMDIIPEKAKAHAIDCMDTISFLPHRAIIRDGGIQELSKMDVIVISVGSLTKNEQRLEELKGSLEAIKSFVPDVVKAGFNGIFVTITNPVDIVTYFVRELSGFPKNRVIGTGTGLDSARLKRILSEVTNIDSQVIQAYMLGEHGDTQIANFSSATIQGVPFLDYMKTHPEQFKGVELSVLEKQVVRTAWDIISGKNCTEFGIGCTCSNLVKAIFHNERRVLPCSAYLNGEYGHSGFYTGVPAIIGSNGVEEILELPLDERERKGFEDACAVMKKYIEVGKSYKIV
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_SULNB
Sequence: MEKKMQNTIAAIATAYGVSSISIIRVSGNAALDIAKKISHLEEVKPRHAHLTSLYNSQNDLIDQAIMIYFKAPFSFTGEEIVEFQCHGGMIVAQEILDTILSYGIRLAEPGEFSKRAFFNGKIDLTEAEAISKLIEAKSVDAAKILAKQMKGELKYFVDESRDALLRSLAYSEVMIDYAEEDIPDDIMRSIVTQLDGLSEQIMKIVDASYRRRGLIEGFKVAIIGKPNVGKSSLLNALLSYDRAIVSDIAGTTRDTIEEQVRIGSHIIRLVDTAGIRESEDTIEKIGIERSLSSVEDADIIIALFDGSREFDSEDEKILAIVDALQDKHIIVAINKSDLEMKLDGDRINSYDPIEVSAKKGFVKLTRQMEALLDSIGEGEELMLISARQIEAVNRAKNAIAEAKEPLMNGELEFFSYHLQEAVKAISSISKPYDSEEILDKMFGEFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_COREF
Sequence: MTRLFGTDGVRGLANKTLTAPLALKLGAAAAHVLTAGTRPHGRRPVAIVGRDPRVSGEMLAAALAAGMASRGVDVLRVGVIPTPGVAFLTDDYGADMGVMISASHNPMPDNGIKFFSAGGHKLPDEVEDEIERVMDDLPEEGPTGHGIGRVIEEAPDARGRYLQHLADAVPTDLSGITVVVDAANGAASVIAPQAYEAAGAKVIAIHNTPNAYNINEKCGSTHMDQIQAAVLEHGADLGLAHDGDADRCLAVDSDGNIVDGDQIMAILAIAMKENSELRKNTLVATVMSNLGLKLAMEKADIQLRTTKVGDRYVLEELNAGGFALGGEQSGHIVLPDHGTTGDGTLTGLSLMARMAATGKPLSELAAAMTVLPQVLINVPVADKSSIMKSANVQAAVAAAEEELGGTGRVLLRPSGTEELFRVMVEAAEQEQARRVAGRLAAVVAEA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HIS62_CAMJE
Sequence: MLKTRIIPCVLLKNSQLVKSIEFKDFRTIGHLTSTMRIYNARNVDELIILDIDASKSGEIDFESIEDLAKECFMPLTIGGGIKTLEDIQKILNLGADKISINSKALEDMDFISKAGNRFGSQCIVCSIDVKRKGDQFCVYDRGNLLEKSPLELALEYEKKGAGELLLTSVDFEGKAKGYDLELLKIFQNKLKIPLIINGGLSKPSDGVEALNLGADALAGAYIFHFSKYTPKDVKEELARQGFAVRLL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Putative imidazole glycerol phosphate synthase subunit hisF2, IGP synthase cyclase subunit, IGP synthase subunit hisF2, ImGP synthase subunit hisF2, IGPS subunit hisF2.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_ACIB5
Sequence: MLASLIGGIFGTKNERELKRMRKIVEQINALEPTISALSDADLSAKTPEFKQRYNNGESLDKLLPEAFAVCREAAKRVMGMRHYDVQLIGGITLHEGKIAEMRTGEGKTLMGTLACYLNALSGEGVHVITVNDYLAQRDAELNRPLFEFLGLSIGTIYSMQEPAEKAAAYLADITYGTNNEFGFDYLRDNMVFSLAEKKQRGLHYAIIDEVDSILIDEARTPLIISGQSEDSSHLYTAINTIPPKLRPQKEEKVADGGHFWIDEKQRSVEMTEIGYETVEQELIQMGLLAEGESLYSATNLNLVHHVSAAIRAHFLFQRDVHYIIHDGEVIIVDEHTGRTMPGRRWSEGLHQAVEAKEGLAIQPENQTLATTTFQNYFRLYKKLSGMTGTADTEAAEMKEIYGLDVVIIPTHRPMIRNDQNDLIYLNRNGKYNAIIQEIMNIRQQGVAPILIGTATIEASEILSSKLKQAGIHHEVLNAKQHEREADIIAQAGSPNAVTIATNMAGRGTDIILGGNWKAKLAKLENPTPEDEARLKAQWEQDHEDVLQAGGLHIIGSERHESRRIDNQLRGRAGRQGDPGVSRFYLSLEDDLMRIFAGDRVVAMMRAMGLKEDEAIEHKMVSRSIENAQRKVEARNFDIRKNLLKYDDVNNEQRKIIYSQRDEILAENTLQEYVEEMHREVMQAMIANFIPPESIHDQWDVEGLENALRIDLGIELPVQEWLEQDRRLDEEGLVERISDEVIARYRQRRAQMGDESAAMLERHFVLNSLDRHWKDHLAAMDYLRQGIHLRGYAQKNPEQEYKKEAFNLFVNMLGVIKTDVVTDLSRVHIPTPEELAEMEAQQQQQAEAMKLSFEHDDVDGLTGEVTASQEALNDSATEQQTFPVPESRNAPCPCGSGLKYKQCHGKI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CX049_MOUSE
Sequence: MGSSEEQSVPGDDFYEESGDLNTGLSLVLRPAKSNEGESSLSSPKGSKLTLVSQLEASENPSVVLWAGEYCPDSLVPEEERVGSPMDEKVVGLDFLSQPSVETTATGQQVTNLETKGAREHPSPESVCAETEAGSIRRAPQASEEAKFAASAGTFFPKGLEQSRSWVTPRKSTTSRMVIGENVHHPTSEPEPLDELNEVQMMRVTICLKDGNHGNQAKNSGPAETGDLARHSNVQTRDSFMRMPSSLLVSTTRGLTSGVERQASKEPEPFSSKKKQGTLWGKGGSKSSYPEAAAGIGALPKASPRKKMAQKKKPLWDASAVTLGRAFHQWGQRLKSAPAEPATFPPISGVGLPGRSNKCSLLPLRPKQCKNLYTGKRSGAKKTKELQLVAKEDTDSTRDPSSQVQFPTHRAEPPCQSVHQEFNSGDINARSLQDAGNSQSSALNQRGIMSKKSVLSGDQEEPVGLPAPDSEILQLPGTQGCPRCPELQKEIEDLRKQLSALQAVSEKFQTHLS
What are the official names of this protein?
Uncharacterized protein CXorf49 homolog.
Protein: TARD_BACSH
Sequence: MKKVITYGTFDLFHYGHMKLLERAKNLGDYLIVGLSTDEFNLQKQKKSHHSYEHRKFILETIDLVNEVIPEKNWEQKISDIQKHDIDTFVIGDDWKGKFDFLKEYCEVIYLPRTDGISTTQIKKDMASL
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to sn-glycerol 3-phosphate so the activated glycerol 3-phosphate can be used for teichoic acid synthesis, via incorporation into both the linkage unit by TarB and TarF.
What are the official names of this protein?
Glycerol-3-phosphate cytidylyltransferase, GCT, GCTase, Gro-PCT, CDP-glycerol pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the cytidylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INX3_CAEEL
Sequence: MLGVPFIDRWLSETFKPKTFDDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFIPERSEIPGDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSVISEAEALRSQDSETRTKGVNKLVDFIGDILDTRSKNEYGRFYCYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFSVRKLANVHRYTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGPVNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGENLQHNRDFHHGHSTKSTSPGLEEGHHEHLYTPEKMKLMAPDYPIKHA
What is the function of this protein?
Structural component of gap junctions (PubMed:10381394, PubMed:33238150).  Plays a role in maintaining gap junction activity to promote phayngeal muscle contraction (PubMed:33238150).
What are the official names of this protein?
Innexin-3, Protein opu-3.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Partially co-localizes with F-actin at gap junctions between EA and EP endodermal precursor cells in embryos.
Protein: RPGF4_HUMAN
Sequence: MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP.  Seems not to activate RAB3A.  Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).
What are the official names of this protein?
Rap guanine nucleotide exchange factor 4, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFII.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: URK_PHOLL
Sequence: MADEAYQCTIVGISGASASGKSLIANTLYRELRAQVGDHNIGIIPEDCYYKDQSDLSMEERYKTNYDHPSSMDHNLLFSHLQALKMGESIELPQYDYVAHTRKPEAIHFAPKRVIILEGILLLTDKRLRQEMDFSIFVDTPLDICLMRRIKRDVHERGRSLDSVIEQYHKTVRPMFLQFIEPSKQYADIIVPRGGKNRVAIDILKAKIGQFCE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCN3_BOVIN
Sequence: MMWPPSLLLLLLLLRRGAQGKPSPDAGPHGQGRVHHAAPLSEAPHDDAHGNFQYDHEAFLGREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRSWIAHTQQRHIRDSVSAAWNTYDTDRDGRVGWEELRNATYGHYEPGEEFHDVEDAETYKKMLARDERRFRVADQDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYTAEPGEEEPAWVQTEREQFRDFRDLNKDGKLNGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRLSKAEILGNWNMFVGSQATNYGEDLTRHHDEL
What is the function of this protein?
Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (By similarity).  Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3 (By similarity).  By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis (By similarity).  Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (By similarity).  This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (By similarity).
What are the official names of this protein?
Reticulocalbin-3.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RS14Z_THEVO
Sequence: MSQVKLQPKKKYGHIDGCVRCGRKRGIVRKYGLHLCRQCFRETARQLGFEKYS
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: AROQ_YERPG
Sequence: MSDKFHILLLNGPNLNLLGTREPEKYGYTTLAEIVSQLEIQAQGMDVALSHLQSNAEHALIDSIHQARGNTDFILINPAAFTHTSVALRDALLGVQIPFIEIHLSNVHAREPFRHHSYLSDIAVGVICGLGADGYNFALQAAVNRLSKSN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.