PharMolix/UniProtQA huggingface dataset:
Protein: PC15_PENCR
Sequence: MERRTVLITGCSQGGIGSALAEVFHQRGFHVFATARKTEKMKHLRDLDRMTLIPLDVTQESQISAAVELIQKHTGGTLDYLVNNAGDGYIIPVLDCDQLHGRQIFEVNFWGPLRMIQEFSPLLIAARGTIVNINSVASETLPLWLGIYSSSKAALLALSETLRLELKPFGVQVLSVMTGAVQTMIFQTNYRLPPDSAYMTWEKQIAAQAEGSEKASRMSATVYAERVVGDILNRQGGITYRGQMASFAYWVVALMPRFLRATPLLAQVGSQ
What is the function of this protein?
Short-chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes penitrems (PubMed:26213965).  The geranylgeranyl diphosphate (GGPP) synthase penG catalyzes the first step in penitrem biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (Probable).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase penC then forms 3-geranylgeranylindole (3-GGI) (Probable).  Epoxidation by the FAD-dependent monooxygenase penM leads to a epoxidized-GGI that is substrate of the terpene cyclase penB for cyclization to yield paspaline (Probable).  Paspaline is subsequently converted to 13-desoxypaxilline by the cytochrome P450 monooxygenase penP, the latter being then converted to paxilline by the cytochrome P450 monooxygenase penQ (PubMed:26213965).  Paxilline is converted to beta-paxitriol via C-10 ketoreduction by the short-chain dehydrogenase PC-15 which can be monoprenylated at the C-20 by the indole diterpene prenyltransferase penD (Probable).  A two-step elimination (acetylation and elimination) process performed by the O-acetyltransferase PC-16 and the P. simplicissimum ptmI-ortholog not yet identified in P. crustosum, leads to the production of the prenylated form of penijanthine (Probable).  The FAD-linked oxidoreductase ptmO then converts the prenylated form of penijanthine into PC-M5 which is in turn transformed into PC-M4 by the aromatic dimethylallyltransferase PC-22 (Probable).  A series of oxidation steps involving 4 cytochrome P450 monooxygenases (PC-21, PC-05, PC-23, PC-20) and a FAD-dependent monooxygenase (PC-14) are required for the transformation of PC-M4 to penitrems A and E.  Synthesis of these final products is proposed to proceed via penitrems D and C (PC-21, PC-05, PC-14) and penitrems B and F (PC-21, PC-05, PC-14, PC-23) (Probable).
What are the official names of this protein?
Short-chain dehydrogenase PC-15, Penitrem biosynthesis cluster protein PC-15.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PGK_TREDE
Sequence: MIKTVKDVNLKDKRIIMRVDFNVPMKDGVVQDDTRIRAALPTIKYILEQGARSLVLMSHLGDPSKDAKKAKEKAEKDGKPFDEEAYINGKHRMKPVAEYLSGLLKLPVDFAPSCMGQLERVKALPQGGILMLENTRFHKEETSKEKAEQQILAKELSLYGDIYVNDAFGTAHRSHASTAEIANFVNTRVAGFLMEKEIKYLEPMLNNPAKPMTAIIGGAKVSSKIAVLESLLKNASSLIIGGGMAYTFLKVQGKKIGKSLFEEDFMDTAKNLLDKAEKQGVKIILPVDHICSETFSPNAEAVLVESTDIPDNLMGMDVGPKTLALYKEIILSSKSIVWNGPVGVFEFEAFSKGTEETARLVAAATEKGALTIVGGGDSVAAVNKFNLADKMSHVSTGGGASLEFLEGKVLPGIACLDTI
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THI4_ARCFU
Sequence: MPLKFTEVMEAEITKAIVETASEEWVEYAESDVIVVGAGPSGLTAARYLAEKGLKTLVLERRLSFGGGIGGGGMLFHKVVVEREAKDILDDFGIRYTEHRNFLVADSAEFMAKLAAKAIDAGAKIIHGVSVEDVIFRDDPLGVRGVCIQWSAVEISGLHVDPLFLRSRAVVDATGHDAEVISVAARKIPLEVSVVGERSAYSEVAEREIVEKTGKIVKGLYAAGMAVAAVHNLPRMGPIFGGMLLSGKKVAEIVAEDLKL
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: EIF3C_YARLI
Sequence: MSRFFAGGSDSDDSSSDEDLYGSGSESGSDFSQDEQDGGDDNDDDMSDDSMFADDSDDDSDDDEDLGGKGASYFLKSSTVADSDDEEDTGKKTVLSAKDKLLAELANCSKLIDNGKRINDWVLIQGEFDKLNKAMERFTKQRHGLPPKVYIQCIVELEEFLNTQLEDKAGIKKMNASNSRAFNTVKQRVRKNNKEYEAAIAKYSSGGDVAEEEEEENKEDKPKPRAKDEFVLTAPSQASNEEFTTVGKAGKALVSPTDMFKTLKTVLESRGKKNTDREDQVRQLENLLPSASTVYQKISVYTMLVSTRLDLSSASAALAPENWLKVVGDLNDLLSILEENIDTYHVIETAPEIEDVEKGPVAREDGVKLIPGSVASLVERVDDEFTKALQFMDPHTTEYVDRLRDETKLYQTLLRVQMYIEHVSDEKDTLGLARILVRRVDHLYFKPNNVINMTEQIAWGGVKGDSKATPRPTEKDLTSSTYPTTLISNMCSVLYKQSNTVFRTKAMLAHVYHYALNDEYYKARDMFLMSHLQSSIASAEPQLQVLFNRTLVQLGLCAFRSGLIAEAQQSLQEVCSSPRLKELLGQGLAKYAQAGVVDKQRVLPFHTHINLELLECVFLCSSLLMEIPFMAAHNTSIDAKKKVISKLFRRMLDYHERQVFCGPPENTRDHIMQAAKALQRGDWEAARDLVCAIKIWSLLPNPEAIKAMLTDKLQIEGLRTYLFTYWNHYSTLSLSTLADMFQLPVKDVAAIVAKMIAQEELPGSLDQKTNSVVFTQAVQQTKLQQLAVALSDKVIQLAERNERLVAGGYQFDKMTQPQKRKTQRAR
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 93 kDa subunit homolog, eIF3 p93, Translation initiation factor eIF3, p93 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_LEGPA
Sequence: MLHLYNSLTRKKEPFVSLRPGKIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFDVTYVRNITDIDDKIIARASERGVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIETIIRLIQRLLEKGNAYVSDNGDVCYEVDTFPEYGKLSHKDIEGLVSGSRVEIVKEKRSPLDFVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIAQSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRSPLNYSEENLLNAKKALIRLYQAVKDVPPQTADSKLDEYWQEQFNQAMNDDFNTPVALSVLFQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSGLAEEEKLVIEQLIAERLQARAERNWAKADQIRADLLSKGIELEDGATGTTWRRIAE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR3_SARBU
Sequence: SPPSQDFMRF
What are the official names of this protein?
FMRFamide-3, SabFMRFamide-3.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CC026_BOVIN
Sequence: MADDLGDEWWENQPAGAASSPGASGGEGGGDTEMTQQETAPGPALSKKVKPPKECFLIQPKETNEDATKTRKRKKKKITDILAKSEPKPGTPEDLQKLMKDYYSSSRSVIELEELTLPDSCFLKANDLTHSLSSYLKEVCPKWVKLRKSHSEKKSVLMLIICGSAIRAVELIRSMTAFKGDSKVMKLFAKHIKVQEQVKLLEKRVVHLGVGTPGRIKELIKQGGLHLNPLKFLIFDWNWRDQKLRRMMDIPEIRKEVFELLEMGVLNLCKTESLKLGLF
What are the official names of this protein?
Uncharacterized protein C3orf26 homolog.
Protein: SURF1_CAEEL
Sequence: MPLPAAAFARILVVSRQRLFNTRIIHTSGSGYSITQCRFYKTTPCLTHKQSQILDLDAPKSRENREKDGGKSKKSKKSIKWSTGSVLMLTIPVFAFSLGIWQTFRLKWKLDLIEHLKGRLNQTAQELPEDLSCESLEPLEYCRVTVTGEFLHEKEFIISPRGRFDPGKKTSAAAGSMLSENEMSSHGGHLITPFRLKNSGKIILINRGWLPSFYFDPETRQKTNPRGTLTLPAIVRKTEKRPQFVGQNVPEQGVWYYRDLNQMAKHYGTEPVLLDAAYETTVPGGPIGGQTNINVRNEHLNYLTTWFTLTLVTMLMWIHKFRK
What is the function of this protein?
Probably involved in the biogenesis of the COX complex.
What are the official names of this protein?
SURF1-like protein.
What is the protein family that this protein belongs to?
Belongs to the SURF1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RT31_YEAST
Sequence: MIATPIRLAKSAYEPMIKFVGTRHPLVKHATEVVVHPCATNGMLPGSKECIPVSKFMENYKPFRVVPIKHSANAGLSSSKTSVFVNRPLQKDELASIFELPARFRYKPINEHELESINSGGAW
What are the official names of this protein?
37S ribosomal protein YMR-31, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RR8_IPOPU
Sequence: MGRDTIAEIITSIRNADMDRKRVVRIASTNITENIVRILLREGFIENVRKHREKNKNFFVLTLRHRRNRKRPYRNIFNLKRISRPGLRIYSNYQRIPKILGGMGVVILSTSRGIMTDREARLEGIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y4105_DICDI
Sequence: MLFENLNNFSLKNNKNINQNIKMSCIKNEKYNDLRICMMVHPVAPVKTQRFVRVEYYP
What are the official names of this protein?
Uncharacterized protein DDB_G0292526.
Protein: DHRS7_DROME
Sequence: MKVQDMDKCAPSSDWNVLYWVLGTVLMPVALPLAIINIWQRFQAQKFRNQLPGKVVLITGASSGLGESLAHVFYRAGCRVILAARRTQELERVKKDLLALDVDPAYPPTVLPLDLAELNSIPEFVTRVLAVYNQVDILINNGGISVRADVASTAVDVDLKVMVVNYFGSVALTKALLPSMVKRGSGHICFISSVQGKFAIPQRAAYSASKHAMQAFADSLRAEVANKNINVSCVSPGYIRTQLSLNALTGSGSSYGKVDETTAKGMSPDKLAERILQCILRKEPDIIVSDVQAKIAYYLRHLCPSLYFWIMAKRAVKLENAEKKST
What is the function of this protein?
Putative oxidoreductase.
What are the official names of this protein?
Dehydrogenase/reductase SDR family protein 7-like.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass type II membrane protein.
Protein: DER_SHEPC
Sequence: MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIEEADVVLFMTDARAGLTAADLSIAQHLRSREKTTFVVANKVDGIDADSACAEFWSLGLGEVYQMAASQGRGVTNMIEYALTPYAEAMGIERQGEEEVVDERQYTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYIPMEREGREYVIIDTAGVRRRSKVHQVIEKFSVIKTLKAVEDANVVLLIIDAREGVAEQDLGLLGFALNAGRALVIAVNKWDGIDQGIKDRVKSELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVIHGNQVSRLPDSYKRYMMNYFRRSLKVVGTPIQLRFQEGDNPFENKTEKLTMSQERRRKRALSHIKDRKTK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ATP9_MARPO
Sequence: MLEGAKLIGAGAATIALAGAAVGIGNVFSSLINSVARNPSLAKQLFGYAILGFALTEAIALFALMMAFLILFVF
What is the function of this protein?
This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase.
What are the official names of this protein?
ATP synthase subunit 9, mitochondrial, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: HFQ_BURTA
Sequence: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARPVNFHPDAEAAS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: TR114_MOUSE
Sequence: MLSTMEGVLLSVSTSEAVLGIVGNTFIALVNCMDYNRNKKLSNIGFILTGLAISRICLVLILITEAYIKIFYPQLLSPVNIIELISYLWIIICQLNVWFATSLSIFYFLKIANFSHYIFVWLKRRIDLVFFFLIGCLLISWLFSFPVVAKMVKDNKMLYINTSWQIHMKKSELIINYVFTNGGVFLFFMIMLIVCFLLIISLWRHRRQMESNKLGFRDLNTEVHVRTIKVLLSFIILFILHFMGITINVICLLIPESNLLFMFGLTTAFIYPGCHSLILILANSRLKQCSVMILQLLKCCENGKELRDT
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 114, T2R114, mT2R46.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SPED_SALSV
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPIDPKLIDQTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDVNGMKHFIDHEINSIQNFMSEDMKSLYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTETERQEITAALWKEMREIYYGRNISAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: TRPC_ACAM1
Sequence: MQIRRRPPSVAVNVQELQYQVKTPENEPRNILEKIVWFKETEVEQMRDSVSLLDLRKQVANCEPPLSFLDALKHGKTQPALIAEVKKASPSKGVLRENFDPVAIAQAYEAAGASCLSVLTDAEFFQGSFDYLQQIRAAVSLPLLCKEFVIYPYQIYLARSRGADAVLLIAAILSDQDLTYFLKIIKSLGMTALVEVHTLPELERVMDIPGIELIGINNRDLETFTVDLEVTCQLLAQQGTSLQDQDILVVSESGLHTSADLAQVKQAGAGAVLIGESLVKETGNASTHSETEQMQAKISALFS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MURG_GEOSM
Sequence: MRLIIAGGGTGGHLFPGIAIADEFLARSPENEVLFVGTERGIEARLLPKLGYKLALISASGMKGMGTIKKIMSAGRLLYGYSQSRKILKEFRPDLVLGVGGYASAPIVLAARGMGVRRFIHEQNAFPGLTNKVLGRIVDGVFISMPEAESFFPKEITQMTGNPIRKEILWGFQERVRSVGDTFSILVFGGSAGAQRVNSALLEALPHLEGVKGKLRITHQTGEKDAARVREGYQAQGVQAQVLSFIDDMSAAYGAADLVVCRAGATTIAEVTACGKGCIFIPFPYAADDHQRKNAESLVHKNAGVMILEEDLTGERLAAKILDLMEHPAELAEMEKNARALAQLDAAQAIVAAMVTKNQERDKDKENQRAR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IF2P_THESM
Sequence: MKKIRQPIIAVLGHVDHGKTSLLDRIRNTHVAEKEAGGITQHIGATEVPIDVVKQLAGPLLSLWKGEIKLPGLLFIDTPGHEAFTSLRARGGSLADLAILIIDVNEGFQPQTLESIEILRKYKTPFVVAANKIDRIKGWKVVENEPFLVNIKKQDQRAQQDLETKLWELIGKFYELGFQVNRFDRVKDFRKELAIIPISAKYGIGVPELLVLISGLAQKYLEEKLKIEVEGPARGTILEVREEIGFGTTIDVIIYDGTLRKDDTIVVGGKDKAIVTKIRALLKPKPLDEIRDPRYKFDHVNEVSASAGIKIAAPDLEEALAGSPVIAVRDEEELKRARREILEQIKSVIISTDKVGVIVKADTIGSLEALSKELHEKNIPIRKADVGNISKTDVMEALSVKEEEPFYGVVIGFNVKVNEDAEEVAKAKNIPLFVNNIIYKLIEDYEAWIKAEEEKKKKEILANTKFPGVIKLFPDERYVFRRSHPAIVGIEVLEGRIKPGYPLIKQNGDKVGVIKSIKSKEDFLQEAKKGDQVAVAIEGAIVGRHIHPGEILYVDISKDDAIRLVKELRDMLDDTDIEALKNTAKVKAQKDPFWGAL
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: DPP5_ARTOC
Sequence: MAPAKWLIASLAFASTGLAFTPEDFISAPRRGEAIPDPKGQFAVFPVSKYNFDTKDRPSGWNLLNLKTGDISVLTTDADVSEITWLGEGTNLLYVNGTDSVKGGVGIWISDAKNFGNAYKAGSIPGAFQGFKLAKSGDKINFVGYGQSTTKGDLYNEAAIEKPVSSARIYDSLFVRHWDAYVGTQFNAVFSGALTKNGNKYSFDGKLKNLVQPVKYAESPYPPFGGSGDYDLSPDGKTVAFMSKAPELPKANLTTSYIFTVPHDGSKVAEPINKRNGPRTPHGIEGASSSPVFSPDSKRIAYLQMATKNYESDRRVIHIAEVGSNKPAQRIASNWDRSPESIKWSSDGRTLYVTAEEHATGKLFTLPSDARDNHMPSAVKHDGSVSAFSFVGSSKSVLITGNSLWSNALYQIATPGRPNRKLFYANEHDPQLKGLGPNDIEPLWVDGARTKIHSWIVKPTGFDKNKVYPLAFLIHGGPQGSWGDNWSTRWNPRVWADQGYVVIAPNPTGSTGFGQKLTDDITNDWGGAPYKDLFKIWEHVRDNLKYVDTDNGIAAGASFGGFMINWIQGQELGRKFKALVSHDGTFVGSSKIGTDELFFIEHDFNGTFFEARQNYDRWDCSKPEYVAKWSTPQLVVHSDYDFRLSVAEGVGLFNVLQEKGVPSRLLNFPDESHWVTKPENSLVWHQQVLGWINKFSGINKSNPKAIKLSDCKVEVIDHEAGSYFDY
What is the function of this protein?
Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini.  Contributes to pathogenicity (By similarity).
What are the official names of this protein?
Dipeptidyl-peptidase 5, Dipeptidyl-peptidase V, DPP V, DppV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF1A_METKA
Sequence: MGKRIDDETLKKIRLPKEGEIFGVVEKMLGNDRVQVRCVDGKTRVARIPGKMRKRVWIREGDVVLVKPWEFQPERADVTWRYTRVQVDWLKRKGKLDERVTKLLEEIIPGA
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: KAD6_SULIY
Sequence: MIIIVTGTPGVGKTVASKKLSEALNLNYLSLSQFVIENKLYTEYDELRQSYIIDEDKVKEELEKIISTSHLVIETIYPSLVSTADLVVVLRKNPFSLYNELKGRGWADIKVAENVEAEILGVISQEAREAFKDKVCEVDTTEMSTEQILNKILNKQCDGPIEWLVDTKVQRFLEELDKIISSYENDI
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
What are the official names of this protein?
Putative adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
Protein: HTPX2_STRCO
Sequence: MHRRHNGLRTAVLLGGLSALIIVIGSFFGRAGLVVAVLVALGTNAYAYWNSDKLALRAMRARPVSEFEAPALYRMVRELSTQARQPMPRLYISPTDAPNAFATGRNPRNAAVCCTEGIMRLLDERELRGVIGHELSHVYNRDILISSVAGALASVIMFLVNFAWLIPVGRSNDDDGPGLLGMLLIMLLGPLAATVIQLAISRSREYEADASGAQLTGDPLALAGALRKLELGTKQLPLPPEPRLETASHMMIANPFRPGQGISKMFSTHPPMAERIARLEKMAGRQQ
What are the official names of this protein?
Protease HtpX homolog 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTDC_BACSU
Sequence: MKKIGIIGAGGIARAHATALSTIKNAELVGVYDINQQNAESFVKTFGGKSFENVDELIDASEGLIVASPNFCHKEHALQALGKHKHVLCEKPMAISLEEASIMKDTAERLSVRASMGFNYRYLSYVNILKSLIINNELGNILSIKVHFKKNSALRRKKFTWRDDANSKKTSGSLGDLGIHLIDMVWYLFESDFITESVRAKMNTNVKTKEDKQVLVDDYAEIYGQLKNKVFVNIITSKCSVPEDCGFSIEVVGHKKEFKYHTGNPHVYKLIDGLNVVDCPVPQSLLNDPPNEFYGWADSFRSELINWIASTQNDWVEIPSFSDGFRSQEVLEMFFEKDSNSQPMSVSAVN
What is the function of this protein?
Involved in the biosynthesis of kanosamine (3-amino-3-deoxy-D-glucose), which is known to have antibiotic and antifungal properties, and to be a precursor of the antibiotic neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose (NTD)).  Catalyzes the oxidation of glucose 6-phosphate to 3-oxo-D-glucose 6-phosphate.  It can only use NAD.
What are the official names of this protein?
Glucose-6-phosphate 3-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: RLUB_BACSU
Sequence: MERLQKVIAHAGVASRRKAEELIKEGKVKVNGKVVTELGVKVTGSDQIEVNGLKVEREEPVYFLLYKPRGVISAAQDDKGRKVVTDFFKNIPQRIYPIGRLDYDTSGLLLLTNDGEFANKLMHPKYEIDKTYVAKVKGIPPKELLRKLERGIRLEEGKTAPAKAKLLSLDKKKQTSIIQLTIHEGRNRQVRRMFEAIGHEVIKLKREEYAFLNLRGLHTGDARELTPHEVKRLRALADHGKNAF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2633 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase B, 23S rRNA pseudouridine(2605) synthase, rRNA pseudouridylate synthase B, rRNA-uridine isomerase B.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: PUR7_SYNS9
Sequence: MTPDHGPLLYEGKAKRVFALAETDRVLVEFKNDATAFNAQKKAQLDDKGRLNCQISARLFELLEQHDVPTHYCGLVDDTWMQVRRVEIIPLEVVLRNVATGSLCRQTPIAEGTGLNPALFDLYYKDDALGDPLLTEARVQLLGVVKADRLSAIEQLARRVNEILCPFFAAIDLQLIDFKLEFGVTSGGELLLADEISPDTCRLWDRRSSDVNDRILDKDRFRKDLGGVMEAYGEVFKRVQSQCPNPRNCL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: TSAD_ENTFA
Sequence: MTIFTKERKLLLAVESSCDETSVAVIEDGDKILSNIVASQIKSHQRFGGVVPEVASRHHVEQVTICIEEALTEAKVTPEELSGVAVTYGPGLVGALLIGLSAAKAFAWAHQLPLIPVNHMAGHIYAARFVAPLEFPLMALLVSGGHTELVYMKEDGSFEIVGETRDDAAGEAYDKVGRVLGLPYPSGKEIDALAHEGTDTYQFPRAMLKEDNYDFSFSGLKSAFINTVHNAEQRGEALSTKDLAASFQASVVEVLVTKTIRACQEYPVKQLLIAGGVAANQGLREAMRHAISEQLPAVTLLIPPLKLCGDNAAMIGAAAFIEAEKNHFASYNLNAEPGVSFMTISEEG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR12_CUSEU
Sequence: MPTIKQLIRNTRQPIRKVTKSPALRSCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
Plastid 30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid.
Protein: YPFN_ECOSM
Sequence: MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPPHRDFNDKWDDDDDWPKKDQPKK
What are the official names of this protein?
UPF0370 protein YpfN.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ASF1_DROME
Sequence: MAKVHITNVVVLDNPSSFFNPFQFELTFECIEELKEDLEWKMIYVGSAESEEHDQVLDTIYVGPVPEGRHIFVFQADPPDVSKIPEPDAVGVTIVLLTCSYRGQEFVRVGYYVNNDYADPEMRENPPTKPLFEKLTRNILASKPRVTRFKINWDYGHINGNGNGVENGHQDEMATDGPSTSEAASAVIHPEDDNSLAMPMENGIKALNENSNSLAMEC
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (PubMed:10591219, PubMed:12381660, PubMed:14561777, PubMed:16151251, PubMed:16396992).  Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly (PubMed:11533245).  Plays a role in the formation of silent heterochromatin (PubMed:12381660, PubMed:28320872).
What are the official names of this protein?
Histone chaperone asf1, Anti-silencing function protein 1, Replication-coupling assembly factor subunit ASF1, RCAF subunit ASF1, dASF1.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.