PharMolix/UniProtQA huggingface dataset:
Protein: VATL_RAT
Sequence: MADIKNNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTDGITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
What is the function of this protein?
Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32165585).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32165585).
What are the official names of this protein?
V-type proton ATPase 16 kDa proteolipid subunit c, V-ATPase 16 kDa proteolipid subunit c, Vacuolar proton pump 16 kDa proteolipid subunit c.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Protein: SYE_SALAI
Sequence: MTVRVRFAPSPTGMFHVGGARSALQNWIFAKQRGGVFVLRVEDTDAARNKPEWTEGILSALEWIGIARGSYEGPYFQSSYAAEHRTAASRLHEGGRAYYCDCTREAVQARTGSPHSGYDGFCRDRDLGPGAGRALRFRTPDEGATVVVDLIRGEPTFENRLIEDFVIARSDGSPVFLLANVVDDMTMGITHVIRAEEHLPNTPKQQLLWEALGVKPPVWAHVPVVVNEKRQKLSKRRDKVALEAYRDEGYLADAMRNYLMLLGWAPSGDREIVPWPVIEEEFRLEQVNPSSAFFDEKKLRAFNGEYIRALPVAEFVAACQPWLTGTATIAPPPWQPDEFDADTFAAVAPLAQTRIAVLSEIVANVDFLFLDSPLIDEGAWAKAMKEGAGDLLDAAITAFTAIPSWDAESTKSALEAVGAEHGLKLGKAQAPVRVAVTGRRVGLPLFESLEVLGRERTLTRLRAARVRLP
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_HERAR
Sequence: MSSNNEILFARAQKSTPGGVNSPVRAFRSVGGTPRFITRAEGPYFWDADDRRYIDYIGSWGPAIVGHAHPDVVKAVQDAATRGLSFGAPTEGEIRMAELICQLVPSIEQVRLVSSGTEAAMSALRLARGATGRDTIIKFEGCYHGHADSLLVKAGSGLLTFGNPTSAGVPEDFAKHTLVLDYNNPQQLEDTFKEIGNQIACVIVEPVAGNMNLLPATPEFLQTMRRVCTQYGAVLIFDEVMSGFRVALGGAQSMYDIKPDLTVLGKVIGGGLPVAAFGGRTDLMQHLAPLGGVYQAGTLSGNPVTVAAGLATLKLIQVPGFYESLATQTGKLVAGLSAAARAANIAFSANSVGGMFGMYFAAEKPQSYTEMMKCDVAHFNTFFHAMLDAGVYLAPSAFEAGFVSAQHDDAIIEASIQAARQAFAQLGQ
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAMA_ENTCC
Sequence: MAMKKLLIASLLFSSATVYGADGFVVKDIHFEGLQRVAVGAALLSMPVRPGDTVNDDDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGESLDRTTLSDIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGVSAKIQQINIVGNHAFTTDELISTFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYITINITEGDQYKLSGVEVSGNLAGHSAEIESLTKIQPGDLYSGSKVTKMEDGIKKLLGRYGYAYPRVQTQPEINDADKTVKLHVNVDAGNRFYVRKIRFEGNDTSKDSVLRREMRQMEGAWLGSDLVDQGKERLNRLGYFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGVGYGTESGVSFQVGVQQDNWLGTGYSVGINGTKNDYQTYSEFSVTNPYFTVDGVSLGGRIFYNDFKADDADLSSYTNKSYGVDGTLGFPVNEYNTLRAGLGYVHNDLSNMQPQVAMWRYLDSIGQSASTSSDNNGFAADDFTFNYGWTYNRLDRGYFPTEGSRVNLNGKVTIPGSDNEFYKLTLDTASYFPIDDDHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNNIGPKAVYYGGNDEDNCASRDPKQVCSSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWDAGTVWDTNWENTAQMRAAGVPDYSDPGNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDKSEQFQFNIGKTW
What is the function of this protein?
Does not normally serve as a receptor for CdiA-EC93, the contact-dependent growth inhibition (CDI) effector of E. coli strain EC93.  However if extracellular loops 6 and 7 are mutated to match the sequence of E. coli then the protein is able to act as a CdiA-EC93 receptor, conferring CDI on E. coli strains expressing the mutated BamA.  The same mutations also support the delivery of CdiA-CT from strain 536 / UPEC.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: YIFE_SALCH
Sequence: MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGHAFNDLDLGKREPVTEEEKLFVAVCRGEREPVTDAERVWSKYMTRIKRPKRFHTLSGGKPQVEGAEDYTEADD
What are the official names of this protein?
UPF0438 protein YifE.
What is the protein family that this protein belongs to?
Belongs to the UPF0438 family.
Protein: RSMA_DEHM1
Sequence: MEKDAPLAATGTPSLMAQAKEMMEGYTLRARKGLGQHFLISQGVLNKILLAADLKPTDTVIEVGPGLGVLTEELIKRAGQVIAVELDDKLVTALTEKFKAYPNFRIIHSDILKTSPAEILGQNIPYKLVANLPYYITSAVLRQFLEAEAKPELMVVMVQKEVAKNMVAQTGDMGLLTLSVRFYGNPSLVSVVPGGAFYPPPEVDSAIVKVAIPQAAIMQGVSEADFFKLARAGFGTRRKTLLNALAQGLGVSKQSVLALLNRAGIEPARRAETLSMEEWKMLCLVYTENPC
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPUF_PSESP
Sequence: MEKLRILICDGNTEADRASFKKFVGCAPSKQFESLLKNYNSQIRTEIAFPADPGPLMTLPLGAYDGILITGSNSHIYEAQPGNLRQIEFAQKAFASGTPMFGVCWGMQLAVVAAGGEVLPSRVADCSCETPFATGVELTSYGSGHPMHHSRTSGFDVFSFHSDEVTRLPGGAVVTARNRNFIQAVEIKHGRSTFWGVQYHPELSGWDQAGFLRESARSLVEDGSYETLNHVEHAAQAISMFKAGAQISEENLVHFEGVDTNSFEFRPLEILNWLDHLVIPTAKRKFGWGGGWLQK
What is the function of this protein?
Involved in the degradation of isopropylamine, which is a constituent of the herbicides atrazine.  Catalyzes the hydrolysis of gamma-glutamyl-L-alaninol (GALO) to L-alaninol and L-glutamate.  It can also uses gamma-glutamyl-isopropylamide, gamma-glutamyl-ethylamide, L-glutamine, and gamma-glutamyl-p-nitroanilide.
What are the official names of this protein?
Gamma-glutamyl-L-1-hydroxyisopropylamide hydrolase, Gamma-glutamyl-L-alaninol hydrolase, Galo hydrolase.
Protein: MYLK2_RABIT
Sequence: MATENGAVELGIQSLSTDEASKGAASEESLAAEKDPAPPDPEKGPGPSDTKQDPDPSTPKKDANTPAPEKGDVVPAQPSAGGSQGPAGEGGQVEAPAEGSAGKPAALPQQTATAEASEKKPEAEKGPSGHQDPGEPTVGKKVAEGQAAARRGSPAFLHSPSCPAIIASTEKLPAQKPLSEASELIFEGVPATPGPTEPGPAKAEGGVDLLAESQKEAGEKAPGQADQAKVQGDTSRGIEFQAVPSERPRPEVGQALCLPAREEDCFQILDDCPPPPAPFPHRIVELRTGNVSSEFSMNSKEALGGGKFGAVCTCTEKSTGLKLAAKVIKKQTPKDKEMVMLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKEQGARMSAAQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV
What is the function of this protein?
Implicated in the level of global muscle contraction and cardiac function (By similarity).  Phosphorylates a specific serine in the N-terminus of a myosin light chain.
What are the official names of this protein?
Myosin light chain kinase 2, skeletal/cardiac muscle, MLCK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: B3GT1_MOUSE
Sequence: MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVARKNFTFGNIRTRPINPHSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWGDENNFKGIKIATLFLLGKNADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDIFVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTGYIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLGIHPFQNSGFNHWKMAYSLCRYRRVITVHQISPEEMHRIWNDMSSKKHLRC
What is the function of this protein?
Beta-1,3-galactosyltransferase that transfers galactose from UDP-alpha-D-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue.  Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins.
What are the official names of this protein?
Beta-1,3-galactosyltransferase 1, Beta-1,3-GalTase 1, Beta3Gal-T1, Beta3GalT1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase-I, UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: THID_BACSU
Sequence: MSIYKALTIAGSDSGGGAGIQADIKTFQELDVFGMSAITAVTAQNTLGVHGVHPLTVETLRQQIDAVAEDLRPDAVKTGMLWNADMIEEVARKIDEYGFNRVIVDPVMIAKGGASLLRDESVATLKELLIPRSYAITPNVPEAETLTGMTISSLDDRKKAAEQLVKMGAQHVIIKGGHQPEDNHITDLLFDGSMFMQITHPYINTKHTHGTGCTFAAALTAQTAKGDSIHQAFEVAANFVREAVENTLGIGSGHGPTNHFAFKRNSLNTSR
What is the function of this protein?
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.  Shows no activity with pyridoxal, pyridoxamine or pyridoxine.
What are the official names of this protein?
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, Hydroxymethylpyrimidine kinase, HMP kinase, Hydroxymethylpyrimidine phosphate kinase, HMP-P kinase, HMP-phosphate kinase, HMPP kinase.
What is the protein family that this protein belongs to?
Belongs to the ThiD family.
Protein: ATPF_CUPNH
Sequence: MNLNATFFAQMVVFFILWWVVAKFIWPPLVKALDERAKKIADGLAAAEKGKAELELANKRVDQAMAEARTEGAQRVADAEKRAQLTADEIKQNAQAEAARIIAQAKAEAEQQVTRAREALRDQVAVLAVKGAEQILKREVNAQVHTDLLNQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: KDSB_BURPS
Sequence: MTSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLDAVREHGFDAVLTRADHPSGTDRLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHLAAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYFSRAPIPWSRDAYLPHWPNVAAMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHAPEAGIDTPADLERVQALFRSRAK
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDHQ_ECOLI
Sequence: MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGAELQQSTITVQQGGVLILDGSTVKGDSVTFIVGNINLNGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
What are the official names of this protein?
Uncharacterized protein YdhQ.
Protein: VINT_BP186
Sequence: MTVRKNPAGGWICELYPNGAKGKRIRKKFATKGEALAFEQYTVQNPWQEEKEDRRTLKELVDSWYSAHGITLKDGLKRQLAMHHAFECMGEPLARDFDAQMFSRYREKRLKGEYARSNRVKEVSPRTLNLELAYFRAVFNELNRLGEWKGENPLKNMRPFRTEEMEMTWLTHDQISQLLGECNRHDHPDLETVVRICLATGARWSEAESLRKSQLAKYKITYTNTKGRKNRTVPISKELYESLPDDKKGRLFSDCYGAFRSALERTGIELPAGQLTHVLRHTFASHFMMNGGNILVLQRVLGHTDIKMTMRYAHFAPDHLEDAVKLNPLVHITNSK
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.  In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
What are the official names of this protein?
Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: SERK4_ARATH
Sequence: MTSSKMEQRSLLCFLYLLLLFNFTLRVAGNAEGDALTQLKNSLSSGDPANNVLQSWDATLVTPCTWFHVTCNPENKVTRVDLGNAKLSGKLVPELGQLLNLQYLELYSNNITGEIPEELGDLVELVSLDLYANSISGPIPSSLGKLGKLRFLRLNNNSLSGEIPMTLTSVQLQVLDISNNRLSGDIPVNGSFSLFTPISFANNSLTDLPEPPPTSTSPTPPPPSGGQMTAAIAGGVAAGAALLFAVPAIAFAWWLRRKPQDHFFDVPAEEDPEVHLGQLKRFTLRELLVATDNFSNKNVLGRGGFGKVYKGRLADGNLVAVKRLKEERTKGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASCLRERPEGNPALDWPKRKHIALGSARGLAYLHDHCDQKIIHRDVKAANILLDEEFEAVVGDFGLAKLMNYNDSHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGVMLLELITGQKAFDLARLANDDDIMLLDWVKEVLKEKKLESLVDAELEGKYVETEVEQLIQMALLCTQSSAMERPKMSEVVRMLEGDGLAERWEEWQKEEMPIHDFNYQAYPHAGTDWLIPYSNSLIENDYPSGPR
What is the function of this protein?
Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates.  Positively regulates the BR-dependent plant growth pathway and negatively regulates the BR-independent cell-death pathway.  Required during SCOOP small peptides (e. g.  SCOOP10 and SCOOP12) perception and signaling; associates with MIK2 as a coreceptor upon MIK2 perception of SCOOP peptides, and relays the signaling through the activation of receptor-like cytosolic kinases (RLCKs) BIK1 and PBL1 (PubMed:34535661).
What are the official names of this protein?
Somatic embryogenesis receptor kinase 4, AtSERK4, Protein BAK1-like 1, AtBKK1, Somatic embryogenesis receptor-like kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HEMA_I34A1
Sequence: MKANLLVLLCALAAADADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGKCNIAGWLLGNPECDPLLPVRSWSYIVETPNSENGICYPGDFIDYEELREQLSSVSSFERFEIFPKESSWPNHNTNGVTAACSHEGKSSFYRNLLWLTEKEGSYPKLKNSYVNKKGKEVLVLWGIHHPPNSKEQQNLYQNENAYVSVVTSNYNRRFTPEIAERPKVRDQAGRMNYYWTLLKPGDTIIFEANGNLIAPMYAFALSRGFGSGIITSNASMHECNTKCQTPLGAINSSLPYQNIHPVTIGECPKYVRSAKLRMVTGLRNIPSIQSRGLFGAIAGFIEGGWTGMIDGWYGYHHQNEQGSGYAADQKSTQNAINGITNKVNTVIEKMNIQFTAVGKEFNKLEKRMENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVKNLYEKVKSQLKNNAKEIGNGCFEFYHKCDNECMESVRNGTYDYPKYSEESKLNREKVDGVKLESMGIYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: Y449_MYCPN
Sequence: MTFSDLLTKLQDNLDIVFNANALKERIQSDPAFAKTIREQLKLLYFLEQKQAKAKTKKKDFQPVFQNLEARFVSLGQTKLANTELNLKLDLTDATDLANYLPIAVCNLFNRDLNSFSKLSSVQPTAVEKTTNGANKPTVTIDLNQPRIHTTGTVSPELENFVNESLEARARQRAFMRVTSERMVGKIFEFQFKSQWIKWAQLAIFISMLLIGAAAIAYLVVVNLLFYRYVNPDSNLTKAVTGQNNTDRPALVDLNGGINLFFPVSASTLITLIFLGFGSTSFLLAFQGKPYSFATRSQTFKAMHFLKHQFGVTDFPRINDNYRYKVRIKWIFWTIFLFVALNALPGGNIITGGILNPSFLLNALRSNELKINSETFKTIFVGFSIFYLASIIPFALISIIAFVLSPKPSSDQTNEVLNRYVQEEMQQPFKTDCDPNNDNDLTPPAVFG
What are the official names of this protein?
Uncharacterized protein MG314 homolog.
Protein: COF1_PIG
Sequence: MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPECAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL
What is the function of this protein?
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed:6509022, PubMed:9078368).  In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed:9078368).  Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity).  Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (By similarity).  Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (By similarity).  Required for neural tube morphogenesis and neural crest cell migration (By similarity).
What are the official names of this protein?
Cofilin-1, Cofilin, non-muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, growth cone. Cell projection, axon. Note=Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.
Protein: ZAR1L_XENLA
Sequence: MASFSEEAMDSYMYPAYNPYSYRYMTPKNKGMSWRQKNYLASYGDTGDYYDNYQRAQLKAILSQVNPNLTPRLRKANTRDVGVQVNPRQDASVQCSLGPRTLLRRRPGALRKPQQSPPEQGSPASPTKTVRFPRTIAVYSPVAAGRLAPFQDKGENLSEKTEALRSEGSRGEGGRPEGKQEDGEIKEQTKMDKADQEEVAPDQTRPKFQFLEQKYGYYHCKDCNIRWESAYVWCVQGTNKVYFKQFCRTCQKSYNPYRVEDIMCQSCKQTRCMCPVKLRHVDPKRPHRQDLCGRCKGKRLSCDSTFSFKYII
What is the function of this protein?
mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation (By similarity).  Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (By similarity).  Binds to the 3'-UTR of maternal mRNAs in immature oocytes, inhibiting their translation (By similarity).
What are the official names of this protein?
Zygote arrest protein 1.L.
What is the protein family that this protein belongs to?
Belongs to the ZAR1 family.
Protein: URED_PSET1
Sequence: MMTLSSMPVTHRADAKSGHSFDANRHWAASLTLGFCAQNSGDTRVTRMNIARHYGPLRVQRPFYPEGKDGCCHVYLLHPPGGVVSGDALNIDISLTKGAHSLITTPAANKLYKADSNGVAWSQTTNLKVDDNATLEWLPQETLAFDGSRGVQVFNIELAKTAKCLGWEILGLGRPASDLPFATGCIEQRFKLTQDGKPLWLERQNLDPTHPRFNGKWGQGGATVHGTFWTVGLSDPTAAIAALREQLPPSNNWAATYRRDVLLVRYLGHERNQVWKLFEQVRNILRPLLSGHQATIPRIWLT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1954_MYCTO
Sequence: MAAGSGGGTVGLVLPRVASLSGLDGAPTVPEGSDKALMHLGDPPRRCDTHPDGTSSAAAALVLRRIDVHPLLTGLGRGRQTVSLRNGHLVATANRAILSRRRSRLTRGRSFTSHLITSCPRLDDHQHRHPTRCRAEHAGCTVATCIPNAHDPAPGHQTPRWGPFRLKPAYTRI
What are the official names of this protein?
Uncharacterized protein MT2003.1.
Protein: SURE_CYAP4
Sequence: MKLLLSNDDGIFSPGIRTLADTLAAAGHEVMVVCPDRERSATGHGLTLFDPIRAEAVASLFHPSVKAWACSGTPSDCIKLALGALLDSLPDFVLSGINQGSNLGTDILYSGTVSAAMEGVIEGIPSMALSLTSFTVREFQPAANFARDLLAKLDHTPLPEAMLLNINVPALPAAEIAGVAITRQGIRRYHDMFKKRVDPRGKTYYWLAGEVLEDVNDPEQGVDSEMLTDVQAIRENLITITPLKYNLTHTPGLQTLSTWLNLPLLLQTDP
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_DESAP
Sequence: MAKGTVGLFDSGVGGLTVVREVSVILPGKRVIYFGDTAHVPYGDKSVDELLSYAERIIGFLCSQGADYIIFACNTSSAVSLRLMRDRFQVPMIGLIEPGAAEAVRLSATGRIGLIATEATVKAGAYARAVSALNRNCQVFSQAAPRLVPLVESGESDTPKAEQAVREYLEPLREQGIDTLILGCTHYPFLRDVIERVLGPEVVLVDPAAATVRAARLDMLRRGFSADNPGAQGEQDTVSLRYFVSGSADAFRAVAGQFLGREPEPVTEICLLR
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: ATCU_SINMW
Sequence: MTALKQTEKSTSLPMSFDFDIEGMTCASCVRRVEKAIAAVPGVASANVNLATERATVQFNGVPETTSVLRAVEKAGYAPRIVTEEIQIEGMTCASCVSRVEKALKAVPGVADASVNLATEKATVRLVSGSAEISALAAAVKGAGYGIRKATPAEAMKEDVDHRTAELRSLKSAVTISSLMTLPLFLLEMGSHFIPGVHDFIMGTIGMRNNLYLQFALATLVLFGPGLRFFRKGVPNLLRWTPDMNSLVVLGTTAAWGYSVVTTFVPAILPSGTANVYYEAAAVIVTLILVGRYLESRAKGRTSQAIKRLVGLQPKTAFVLHSGEFVETEITEVVTGDVIRIRPGEKIPVDGTVTDGSSYVDESMITGEPVPVQKATDSAVIGGTINKTGSITFKATKVGSDTLLAQIIRLVEAAQGSKLPIQALVDRVTAWFVPVVILAALLTFAAWYVLGPSPALSFALVNAVAVLIIACPCAMGLATPTSIMVGTGRAAELGILFRKGEALQSLRDADVVAVDKTGTLTKGRPELTDLVAAEGFEPDEVLCLVASLETLSEHPIAEAIVSAAKSRGIATVAVSAFEATPGFGVSGTVSGRRVLVGADRALVKNGIDITGFADEAERLGSGGKSPLYAAIDGRLAAIVAVSDPVKESTPQAIKSLHALGLKVAMVTGDNRRTAEAIAKKLGIDEVVAEVLPEGKVDAVRKLRQGGRSVAFIGDGINDAPALAEADVGIAVGTGTDIAIESADVVLMSGDLNGVAKALALSKATIRNIKQNLFWAFVYNISLVPVAAGVLYPVNGTLLSPIFAAAAMAMSSVFVLGNALRLKSFDPA
What is the function of this protein?
Involved in copper efflux.
What are the official names of this protein?
Copper-transporting P-type ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FKBP1_RHIO9
Sequence: MGVTVETIQPGDGKNFPKKGDTVTMHYTGTLQNGSVFDSSVRRNEPFVTQIGVGRVIKGWDEGVLQLSLGQKANLICTPDYAYGPRGFPPVIPPNATLNFEVELLKIN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 1, FKBP, Peptidyl-prolyl cis-trans isomerase, PPIase, Rapamycin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.