PharMolix/UniProtQA huggingface dataset:
Protein: DNAG_ENTFA
Sequence: MAQRIPQEVIEEVRHRTNIVDIIGQYVQLKKSGKNYMGLCPFHEERSPSFSVAEDKQIFHCFGCGKGGTVFNFLQEIEGISFPESVKRVADLEHLSVDFDWSEPREVADTPENQQRRSLLQLHSKAAELYHHILVNTKIGEPALNYLLERGLTQELIETFQIGFAPQKRDFLSQVFKNEQLDETLFEPSGLFVQRDNGTFLDRFYQRIMFPINDPQGNVIAFSGRLLKTADFPGDEMPKYLNSPETTLFNKRETLFNFDRARKEIRKENTVLLFEGFMDVIAAWQSGVKSGVASMGTSLTNEQIRRLERVAKEVVICYDGDNAGVQATNRAIQLLQENSHFDLSIVSIPEKLDPDEYVRKYGAEAFQNLANHGRETVFSFKMNYHRLTRNMNNEKEQLDYVNELLRELTNVQSPLERDRYLNQIAQEFQLSVHSLEEQFNQLKQEQRSVQRQERQQFYQDEMMPPPMEEPVFEENHVQNKLPLTQVQKAERSLLFRLMNEQGVRQTIQQLPDFSFAHDEYQELYFLLESYATLHQSFDIADFINFLQDNQTKQLAIEIAYQNLSEESSEREVADLLHVIALSSIAEAIEQKKIQQQEAKRVGNQQLEAELTMEIIQLARQLKAQRTFT
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: TOLB_PSEAE
Sequence: MSTLIRIALFALALMAGAAQAADPLVISSGNDRAIPIAVVPFGFQGGNVLPEDMSNIIGNDLRNSGYFEPLPRQNMISQPAQASEVIFRDWKAVGVNYVMVGNIVPAGGRLQVQYALFDVGTEQQVLTGSVTGSTDQLRDMSHYIADQSFEKLTGIKGAFSTKMLYVTAERFSVDNTRYTLQRSDYDGARPVTLLQSREPIVSPRFSPDGRRIAYVSFEQKRPRIFIQYVDTGRREQITNFEGLNGAPAFSPDGNRLAFVLSRDGNPEIYVMDLGSRALRRLTNNLAIDTEPFWGKDGSTLYFTSDRGGKPQIYKMNVNSGAVDRVTFIGNYNANPKLSADEKTLVMVHRQQGYTNFQIAAQDLQRGNLRVLSNTTLDDSPTVAPNGTMLIYATRQQDRGVLMLVSINGRVRIPLPTAQGDVREPSWSPYLN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DUT_MYCLE
Sequence: MSTSLAVVRLDPGLPLPSRAHDGDAGVDLYSVEDVKLAPGQRALVRTGLAVAIPFGMVGLIHPRSGLAVRVGLSIVNSPGTVDAGYRGEIKVALINLDPVEPLVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLAETSRGDGGHGSSGGHASL
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TRUB_MYCSK
Sequence: MSGAGVGGGIVIVDKPAGMTSHDVVGRCRRIFGTRKVGHAGTLDPMATGVLVVGIDRATKLLGLLTATDKSYEATIRLGQTTTTEDAEGDVVETTPATGITDEQIGHAVAALRGEIDQVPSAVSAIKVGGQRAYKLAREGQTVELAARRVRIDRFEVLAIRRVDGFVDVDVAVDCSSGTYIRALARDVGVTLGVGGHLTLLRRTRVGRFGLDEAYPLDALADEPRLSHSLDEACLLSFPRRDLTPAEAESTRHGRALAPAGIDGVYAAAAPDGSVLALLEDGPQRTKSVVVLRPATL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: DGTP2_ESCF3
Sequence: MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHLGEAAINDWFRQRLHPEDAESQPLTDDRCSVAGLRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVERLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTPHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: MURQ_SYNY3
Sequence: MPMEILEERGHLLTEQTNPQSQNLDQLSSLELVDLFNQQDQLTVTAIAGAREDLAAAIEIISDALAKGGRLFYIGAGTSGRLGVLDAVECPPTFCTPSELVQGILAGGASALLRSSEGLEDIAADGAQAIADHRITQLDVVVGITAGGTTPYVHGALDAARARGTKTIFIACVPESQAPCQADVNIRLLTGPEILAGSTRLKAGTVTKMALNILSTGAMVKLGKVYGNRMVDVAVTNRKLEDRAIRILRDLTDLNREEAAELLVASGQRVKLALLMHWSGLSAESAQAQLDRHGGNLRQAMDAAP
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: RL332_LEVBA
Sequence: MRVHITLECTECHERNYLSSKNRRNNPDRVEFKKYCPRDRKVTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TPIS_STRPD
Sequence: MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAPAVDLVTTIESAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDYFHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQVASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPENVKDYMACPDVDGALVGGASLEADSFLALLDFLN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_EPTFU
Sequence: MTNIRKSHPLLKIVNSSFIDLPAPSSISAWWNFGSLLGVCLALQILTGLFLAMHYTSDTTTAFTSVTHICRDVNYGWMLRYLHANGASMFFICLYLHVGRGLYYGSYLYKETWNMGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIISAMVMVHLLFLHETGSNNPTGIPSNADMIPFHPYYTIKDILGLFMMITALLALVLFAPDMLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVASILILIIIPLLHTSKQRSMTFRPISQCLFWLLAADLLTLTWIGGQPVEHPYVIIGQLASILYFLIIIVLMPLIGLMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNJB6_XENTR
Sequence: MVEYYDVLGVQRNASPEDIKKAYRKLALKWHPDKNPDNKDEAERRFKEVAEAYEVLSDSKKRDIYDKYGKEGLTGGGGGSHFDNPYEFGFTFRSPDDVFRDFFGGRDPFSFDLFADDPFDDFFGRRGHRANRSRPGGSFLSTFGGFPAFGPTFSPFDSGFSSSFGSFGGHGGFSSFSSSSFGGSGMGNFRSVSTSTKVVNGRRVTTKRIVENGQERIEVEEDGQLKSLTINGKEQLLRLDNK
What is the function of this protein?
Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70.  Plays an indispensable role in the organization of KRT8/KRT18 filaments.  Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin.  Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins.  Also reduces cellular toxicity and caspase-3 activity.
What are the official names of this protein?
DnaJ homolog subfamily B member 6.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus.
Protein: RL1_SALPK
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFNESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGPNAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSQAKGVYIKKVSISTTMGAGVAVDQAGLSASAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: IF5A_SPOEX
Sequence: MADIEDTHFETGDSGASATFPMQCSALRKNGFVMLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFNGKKYEDICPSTHNMDVPHVKREDYQLTDISDDGYLTLMADNGDLREDLKIPDGDLGTQLRSDFDSGKELLCTVLKSCGEECVIAVKANTALDK
What is the function of this protein?
mRNA-binding protein involved in translation elongation.  Has an important function at the level of mRNA turnover, probably acting downstream of decapping.  Critical for the efficient synthesis of peptide bonds between consecutive proline residues.  Can resolve ribosomal stalling caused by consecutive prolines during translation (By similarity).  Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity.  Functions as a regulator of apoptosis (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 5A, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_LACDB
Sequence: MMQEMTPEEIKEKKPYLDWSLSEEEYDYICDKLLHRLPNYTETGLFAAMWSEHCSYKKSKSVLRLFPTKGPRILQGPGEGAGVVDIGDGQAVVFKAESHNHPTAVEPYQGAATGVGGILRDVFSMGARPVATLDSLHFGELDDAHTRWLLNETVAGIGGYGNCMGIPTVGGELTFDDIYKGNPVMNAMSVGLLDVKDMQKGLAQGEGNAVMYVGAKTGRDGIHGATFASHSFDSEHESQRSAVQVGDPFMEKLLLEACLELTQKHADWLVGIQDMGAAGIVSSSSEMASEGKSGMELNLDLVPQRESGMSAYEIMLSESQERMLLCVKKGHEEDVKKIFDFYDLDAVVIGRITSGHNYVLRHHGEVVCDIPVTSLTEDVLEEPSEEKQPQHMIDDAAKPAWEPEITDLAKTYKQMLAQPTIASKGMFTQTYDSMVRTSTVVGPGEDSGVLRVRGTHKGIAMTTDGNGRFIYLDPEIGGKRAVVEAAGNIIASGAEPLAITDCLNFGNPNEPEVFWELHHSVMGIAKACEVLETPVVSGNVSLYNETDGKSIYPTPMVGMVGLVKNLDHLVRDSFQEEGDDLYLVGQTGADYAGSELQKMLTGEIFGSLNDLDLDHIKDYQKRLLAQMEAGHVASAHDLSEGGLAVSLAESSFGHGIGAEVACDLTSAELFSETPGRFLVSVPSEYSAEFAAALAADAVKIGQTAGDSLKLTLKDQAADLPVAELKQIWEEALPCLMKSKD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_SALPC
Sequence: MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVGLGFALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPVGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFWKIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGVPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDERLANNALRS
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1590_LISMF
Sequence: MFTESMLFLLLFLLLGLIAKNNSLIIAVAVVILLKLFHVDGKAMEMIQAKGINWGVTIITVAILIPIATGQIGFKDLIDSFKSAAGWIGLGAGIAVSILAKKGVGYMAVDPQVTVSLVFGTILAVVLFRGIAAGPVIAAGIAYMAMQLVAFIK
What are the official names of this protein?
UPF0756 membrane protein LMOf2365_1590.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PFKA_SALPA
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVVPEVEFNREDLVAEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLEGHGGRCVGIQNEQLVHHDIIDAIENMKRPFKSDWMECAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMFH_ECOLI
Sequence: MVNAAQRTRVKVEADNRPSVDTHPPGVQPSPGTGGTRHHNFMLCVVLAVPVFSLVLSGTALFTKQRRVSPDDGLITRPILIAVATGALLCFVEKLTDRAGSIC
What are the official names of this protein?
Putative protein YmfH.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROA_METMA
Sequence: MANDIESKVIKAKKASIELASVSSEVKNRALEAMAEALDKERKIILEANLKDLEYAAQLKKAGKLTQALVDRLKVTDSKVDGMIAGIRDVIKLKDPVGETLSTLELDDDLILYQVSCPIGLIGVIFESRPDVVPQVMSLCLKSGNATIFKGGSEARESNRTIFDILVRAIESTGGMPEGAFQLMETREEIMSLLSLDAYVDLLIPRGSNEFVKFIQDNTKIPVLGHTSGICHIYVDEFADPDTAWQVCFDAKVQYPAVCNAIETLLVNRNIAEVFLPKMAEMYLKAGVELRCDEGSYSLLSEKGLSPLSRATDEDWSLEYNDLILSIKLVDTIKEAVDHINTFGSHHTDGIITENASRRKEFIGLVDSSSVMVNASTRFADGYRYGKGAEVGISTNKIHSRGPVGMEGLLIYKYILMGKGQVVADYAGKNAKPYTHRKLDLKFEDVN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQB_RHOPT
Sequence: MLRVIVLGAAAGGGVPQWNCGCPVCRAAFDDPRLARTQASLAISADNAHWFLINASPDLRQQIIATPQLHPRAGALRHSPIAGVILTNGEVDAVAGLLSMREGAPFSIYAHDKVLAILRANSIFNVLNESIVARRPVATDQPFEPLLPDGTPSGLEITAFEVPGKGAWYLEGRTHPGGDSQSGDTLGLTITDKSTGQSLHVLTACARVTDDLKARLAGAPLLLFDGTVWRDDELITAGLGTKTGQAMGHIAMAGDDGAIAALADLDIGQKLFVHINNSNPALLAHSAERGQLETAGWQIPADGTEVTL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: CARDE_CYNCA
Sequence: DSGSAIVALTNDRDTSYFGEIGIGTPPQKYTVIYDTGSSVLWVPSSKEQDFIEATDETDNVFLHRRFSFWLNRNVDEEEGGELVFGGLDPNHFRGDHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPTAIVTQINHAIGANSEELNVKFGLTPEQYILKGEATQCISGFTAMDATLLGPLWILGDVFMRPYHTVFDYGNLLVGFAEAA
What is the function of this protein?
Aspartic protease with a high preference for bonds between hydrophobic residues.
What are the official names of this protein?
Cardosin-E.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Microsome membrane. Protein storage vacuole. Secreted, cell wall. Secreted, extracellular space, extracellular matrix. Note=Procardosin-E is associated with the microsomal membranes, the mature form is secreted.
Protein: NUOB_LEGPL
Sequence: MAVAELEKKGFELTTVEKLVGWARSGSMWPMTFGLACCAVEMMHVGAARYDLDRFGIIFRPSPRQSDVMIVAGTLCNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALLYGIIQLQNKIRRKPVLEA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AGRP_MOUSE
Sequence: MLTAMLLSCVLLLALPPTLGVQMGVAPLKGIRRPDQALFPEFPGLSLNGLKKTTADRAEEVLLQKAEALAEVLDPQNRESRSPRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTATNLCSRT
What is the function of this protein?
Plays a role in weight homeostasis.  Involved in the control of feeding behavior through the central melanocortin system.  Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland.  Has very low activity with MC5R.  Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity (By similarity).  It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner (By similarity).
What are the official names of this protein?
Agouti-related protein.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus lumen.
Protein: APMAP_RAT
Sequence: MTFLMLAVSLAIPLLGAMMLLESPIDPQSFSFKEPPFMFGVLQPNTKLRQAERLFENQLNGPESIVNIGDVLFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPTCGRPLGIRVGPNGTLFVVDAYKGLFEVNPQKRSVKLLLSSETPIEGKKMSFVNDLTITRDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTKEVKVLLDQLQFPNGVQLSPEEDFVLVAETAMARIRRVYVSGLMKGGADMFVENMPGFPDNIRPSSSGGYWVAAATIRANPGFSMLDFLSDKPFIKRMIFKLFSQETVMKFVPRYSLVLEVSDSGAFRRSLHDPDGQVVTYVSEAHEHDGYLYLGSFRSPFICRLSLQSI
What is the function of this protein?
Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate.  May play a role in adipocyte differentiation (By similarity).
What are the official names of this protein?
Adipocyte plasma membrane-associated protein.
What is the protein family that this protein belongs to?
Belongs to the strictosidine synthase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DLDH2_ARATH
Sequence: MAMASLARRKAYFLTRNISNSPTDAFRFSFSLTRGFASSGSDDNDVVIIGGGPGGYVAAIKAAQLGLKTTCIEKRGALGGTCLNVGCIPSKALLHSSHMYHEAKHVFANHGVKVSSVEVDLPAMLAQKDTAVKNLTRGVEGLFKKNKVNYVKGYGKFLSPSEVSVDTIDGENVVVKGKHIIVATGSDVKSLPGITIDEKKIVSSTGALSLTEIPKKLIVIGAGYIGLEMGSVWGRLGSEVTVVEFAADIVPAMDGEIRKQFQRSLEKQKMKFMLKTKVVGVDSSGDGVKLIVEPAEGGEQTTLEADVVLVSAGRTPFTSGLDLEKIGVETDKGGRILVNERFSTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEFIAGKHGHVDYDKVPGVVYTYPEVASVGKTEEQLKKEGVSYNVGKFPFMANSRAKAIDTAEGMVKILADKETDKILGVHIMSPNAGELIHEAVLAINYDASSEDIARVCHAHPTMSEAIKEAAMATYDKPIHM
What is the function of this protein?
Lipoamide dehydrogenase is a component of the glycine decarboxylase (GDC) or glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes.  LPD1 is probably the protein most often associated with the glycine decarboxylase complex while LPD2 is probably incorporated into alpha-ketoacid dehydrogenase complexes.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase 2, mitochondrial, AtmLPD2, mtLPD2, Dihydrolipoamide dehydrogenase 2, Glycine cleavage system L protein 2, Pyruvate dehydrogenase complex E3 subunit 2, E3-2, PDC-E3 2.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RDGC_ENT38
Sequence: MLWFKNLMVYRLSREVSLQAEEMEKQLAAYTFTPCGSQDMAKTGWVAPMGSQSDALTHTTNGQIILCARKEEKILPSPVVKQALEAKIFKLEAEQGRKLKKTEKDSLKDEVLHSLLPRAFSRFNQTMMWIDTVNDLIMVDCASAKKAEDTLALLRKSLGSLPVVPLTMENPIELTLTEWVRSGSPAQGFQLLDEAELKAILEDGGVIRAKKQDLVCDEIAVHIEAGKLVTKLALDWQQRIQFVMCDDGSIKRLKFCDELRDQNEDIEREDVSGRFDADFILMTGELAALIKNLVEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MYH6_MESAU
Sequence: MTDSQMADFGAAAEYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKIVSREGGKVTAETENGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPAHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRSKKDNPNANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELLATDSAFDVLGFTAEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALGKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNVKGKQEAHFSLVHYAGTVDYNILGWLEKNKDPLNETVVGLYQKSSLKLMATLFSTYASADAGDSGKGKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQARGQLMRIEFKKMVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKESLEKSEARRKELEEKMVSLLQEKNDLQFQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTSKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLNVTQESIMDLENDKLQLEEKLKKKEFDISQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLTRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEESQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEEMEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSQANRIASEAQKHLKNAQAHLKDTQLQLDDALHANDDLKENIAIVERRNTLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMEADLTQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLVRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQKMHDEE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-6, Myosin heavy chain 6, Myosin heavy chain, cardiac muscle alpha isoform, MyHC-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.