PharMolix/UniProtQA huggingface dataset:
Protein: GCSP_VIBC3
Sequence: MTELLHSLSTQNEFVARHNGPDKQEQATMLKTVNAESLDALIAQTVPAQIRLEAPMQLAPAQSEADMLATMKSFAKLNQLKRTFIGQGYYNTFTPNVILRNVMENPGWYTAYTPYQPEISQGRLESLLNYQQMVMDLTAMEIANASLLDEATAAAEAMALCQRAGKSKSNLFFVADDVHPQTIEVVKTRAAFLGFEVKVDSIDNITQQEAFGALLQYPGTTGEVRDLTDIIAKAQANKTLVTVATDLLASVLLKPAGEMGADVVIGSAQRFGVPMGYGGPHAAFMATRDAHKRTMPGRVIGVSIDAKGNQALRMAMQTREQHIRREKATSNICTAQALLANMAAFYAVYHGPQGLRTIARRAHHLTAILAAGLTKAGYELAHQHFFDTLAINTGAKTDALYQAAQQANINLRKLPNQLGVSFDETTTVADVEALFAIFGIKEEVHALSDRIATNELAAIPESCRRQSAFLTHPVFNTHHSETQMLRYMKHLENKDFSLTHGMIPLGSCTMKLNATAEMIPVTWPEFGALHPFVPKAQAAGYAALAEDLKQKLCEITGYDAFSLQPNSGASGEYAGLVAIQRYHQSRGEGHRNVCLIPSSAHGTNPATAAMVSMKVVVVKCDENGNIDMVDLADKIEKHKDHLSSIMITYPSTHGVYEQQVREVCEMVHAAGGQVYLDGANMNAQVGLTSPGFIGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKSHLAPFLPGHIEGGVEGSDFAVSAADLGSASILPISWAYIAMMGADGLAEATKLAILNANYVMERLRPHYPILYRGANGRVAHECIIDIRPLKEETGISEEDIAKRLMDYGFHAPTMSFPVAGTLMVEPTESEDLAELDRFCDALIAIRGEIDKVKNGEWPLESNPLVHAPHTQADLREEKWDRPYSREIACFPSAHTKASKYWPTVNRVDNVYGDRNLVCSCPSIDSYQD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: SLAM1_HAEIN
Sequence: MSIQTKFILFLSSSLFLTPYSVATEKSPQPHDGRLDEQLHLAKPNLPQKTPALLTNNNPSKLSITKEELAKHPDLIIRGLIPAVLQNNGEAVQLLLPLYQPLPKKDPFLLEWAEAIDLREKGYFSDSVKAYRHLFSQKTDLLPLRYQLAQALFLNNDNEAAKDQFQKLRAEQVSSDSVKIIEQYLSALNQRDQWKIQGGFSFLNESNINNAPKAGTKIGNWTAWEKESARGFSYFGNAEKKWSLPHNHFTKLSLEGSGKYYWDNKKYNEFNARAGVGLGYQTARFELSLMPFTEKRWYAGGSSGGNAMKQYSKNSGARLDLSNWLNEKWQISTALEYGEQRYETRKHLNGNNYLASATLLYLAKSGQYWFGGADYNRENTRDLDNAYQRKNVRLGWGQEWKAGISTRLILNYARRAYKEKDLIGIRQKNKEYASVLTIWHRNFHIWGITPKLSWSYQKVTSNHPFYEYDKNRIYVEISKTF
What is the function of this protein?
Required for correct export to the cell surface of some cell outer membrane lipoproteins.
What are the official names of this protein?
Surface lipoprotein assembly modifier 1, Slam.
What is the protein family that this protein belongs to?
Belongs to the Slam family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RL31_METMA
Sequence: MVGKMADDMVKEQIYTIPLREVRKVPAWKRAGRAVKEVRGFLVRHMKTEAEQVKLDKTINECLWEKGCEKPPLSIRVRAVKFADGEVQAELAQ
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: ARGB_METTH
Sequence: MKTVNILVEALPYIKKFHRKKIMIKYGGHAMIDEAAMDSTARDTVLLKYVGMEPVVVHGGGPEISRAMNKMGKEPKFIEGLRVTDEETMEIVKMVLVGKINTSIVSKICYHGGRAIGLSGKDSNLLLARKRAPHVVRDDETGERREIDLGLVGEIESVDPGIINMLTDNNYIPVISPIGVDRDANTLNLNADTVAGEVAAGIGAEKLIVLTDVPGILEDPSDPDTLIRRISVDELSDLVKSGIVEGGMLPKTLTCIQAINDGVSSAHIIDGRVEHSLLLEIFTKKGIGTMITE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_SHISS
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: VG430_BPPF1
Sequence: MKTPIHPTRLVLEENGDFHKSPKGMLFMDPLNGQFTDLSGVRILRCGVDTVRQLYNGKLRPEVMALFDLSVDVVEFAGYEWSKGRIGRDSGYQYRLQNAEMGLILLIKNHNIKVDTIGSHLKIEVSPHAIDGADPRILQGVLDDLAAAVLSHCETNQAAVHIALDVQGWTPPADLVDRMHCRSRRVRQISGIERIEFDGNASVYGRGETYMFGSANGLQLSIYNKTLQARATDKLDYWESVWATLNGDPFGDGDPAYNPLETVWRIEFRYHHSIVQQFSEGSRMASGEVIGCRTYEGLCPHLQGLWNYACEAFRVLSREGMYDAFWSLISLDARVQVECDPLIERTEYRRYYKTAKGFSGRNCEMFLGQFVSLIARERVPAKKAIESARKLEFWHVIEDHYLAKGWTRRDLERHIHKLMCDRYLRKGYAI
What is the function of this protein?
May play a role in phage assembly.
What are the official names of this protein?
Uncharacterized protein ORF430, ORF430.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: LIPA_HAEDU
Sequence: MTTAIGKKTTKLEPFKMERGVKYRDAAKTSVIQVRNIDPDQELLKKPEWMKIKLPTNSAKIDSIKYGMRRHGLHSVCEEASCPNLHECFNHGTATFMIMGAICTRRCPFCDVAHGKPLPLDPYEPRKVAETVQDMKLKYVVITSVDRDDLADRGAAHFAATVREIKALNPECKVEILVPDFRGRVEQAVAILKQNPPDVFNHNLENVPRLYREIRPGADYKWSLELLKIFKQEFPNIPTKSGLMVGLGETNEEILAVMQDLRDHGVTMLTVGQYLQPSRHHLRVERYVPPAEFEMFRSEAEKMGFEHAACGPFVRSSYHADLQAKGELVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_SHEWM
Sequence: MTEQVLPDENKLIAERRAKLEHIRANCPANGHPNNFDRKHKAADIQAEFGNNTKEELEGMGIQRSIAGRIMAKRGPFLVIQDVSGRIQAYAGKDVQKDLKATFQGLDIGDIIGVTGQLHLSGKGDLYVNMEEYQLLTKALRPLPEKFHGLTDQETRYRQRYVDLIVNEDSRNAFIMRSKVVSAIRNFMVKKEFMEVETPMMHSIPGGASARPFETHHNALDIAMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADFNDLMDLTEEMLSSIATELCGSPQLPYGEHTVDFGGPYARLSMLDAIKKYNPDNATIQSMTYEEVKDVEFMRDLAKSLGMTIEKFWTCGQLLEEIFGETAETQLMQPTFITGYPADISPLARRNDDNHFITDRFEFFIGGREVANGFSELNDAEDQDNRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVMLFTNTHTIRDVILFPAMRPQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_BORPD
Sequence: MKALLDLFKQVSQDEQFDAIKIGIASPEKIRSWSYGEVRKPETINYRTFKPERDGLFCSKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTVAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAWCVIEPGMTPLKRGQIMSDDDFLAKTEEYGDDFRALMGAEAVRELLRTIDIDREVETLRGELKATSSEAKIKKISKRLKVLEGFQKSGIKAEWMVMEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIILRNEKRMLQEAVDSLLDNGRRGKAMTGANKRQLKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFIFNRLEMMGLATTIKAAKKLVESQEPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARTLMLASNNVLFPANGEPSIVPSQDIVLGLYYTTRERINGKGEGIFFTDVAEVQRAYDNGEVELQSRITVRLTEYERDDNGEFQPVLRRHETTVGRALLSEILPKGLPFTVLNKALKKKEISRLINQSFRRCGLRDTVIFADKLMQSGFRLATRGGISIAMGDMLIPKAKEGILAEASREVKEIDKQYSSGLVTSQERYNNVVDIWGKASDKVGKAMMEQLATEPVVNRHGEEVRQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVITEDDCGTTQGYAMKALVEGGEVIEPLRDRILGRVAAIDVVDPDTQETAIAAGTLLDEDLVDLIDRIGVDEVKVRTPLTCETRHGLCAHCYGRDLGRGSHVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRSALASAVETKSTGKVGFASTMRYVTNAKGERVAISRSGELAIFDDNGRERERHKIPYGATVLVGDGEAVKAGTRLATWDPLTRPIVSEYGGAVRFENIEEGVTVAKQLDEITGLSTLVVITPKTRSGKTVTRPQIKLVNENGEDVKIAGTDHSVNISFPVGALITVRDGQQVAVGEVLARIPQESQKTRDITGGLPRVAELFEARSPKDAGMLADVTGTVSFGKDTKGKQRLVITDLEGVSHEFLIPKEKQVLVHDGQVVNKGEMIVDGPADPHDILRLQGIEKLATYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVNIVDAGDTEFIPGEQVERSELLNENDRVTAEGKRPATYDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAYHMARKDKEALEAAEREAARQLANPFEDAPVTVDADAPQSDAGQEGSAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: Y1692_RHOP5
Sequence: MTVLAAHRLQGAEPLLPSLQARLACRAGNAQQTAGVAPGFVQGNLAILPEKLAASFHRFCQLNPKPCPIIGMSDVGDPNLPALGRDLDIRTDLPRYRVWRDGELVDEPTDILAHWRDDLVAFVIGCSFSFEEALLADDLPIRHIELGVRVPMYRTNIACAPSGPFAGPMVVSMRPMKPADAIRAVQITSRFPAVHGAPVHLGLPQSIGITDLAKPDYGDPVPINDDEIPVFWACGVTPQAVIAAARVPFAITHSPGLMLVTDLKNKQLAVL
What are the official names of this protein?
Putative hydro-lyase RPE_1692.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: PSBB_AETGR
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWNITGGTITNPGLWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQPVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYEWDQGYFQQEIYRRVSAGLAENQSLSEVWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRNKEGRELFVRRMPTFFETFPVVLVDGDGIVRAYVPFRRAESKYSVEQVGVTVELYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTKRQAA
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL10_VARPS
Sequence: MSLNRSEKEAVISDVTSLAAKAQTLVMAEYRGITVADMTKLRSEARSKGVTLSVLKNTLARRAVAGSAFEIVGDQMTGPLIYGFSEDAVAAAKVVADFAKTNDKLVIRGGAFGGKALDVNGVKQLANIPSKEVLLAQLLGLMQSPISRTARVLAALAEKRGGGEAAPADAPAEAQAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PROA_ECOL5
Sequence: MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSESILNANAQDVADACANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_BRUA1
Sequence: MSNLPFTVAALYCFAPLPQYESLREPLAQLCCANGIKGTLLLAAEGINGTVAGSAGAIEKLIAHITAIPGLGEPELKYSHASEMPFHRMKVRLKREIVTMGVEGIDPLKSVGTYIAPKDWNALIADENTVVVDKRNDYEYAIGTFEGAIDPQTRTFREFPEWVKQNRDRLEGKKIAMFCTGGIRCEKATAFVKGLGFDDVYHLKGGILKYLEEVPREQSMWNGECFVFDERVAVGHGLAESDVELCRACRRPLTPQDKLSQFFEEGVSCAGCYAERTPEDRARYAERQKQVKLAEKRGANKHIGS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ATP6_RICM5
Sequence: MTHSPLAQFDIKKLIDIKMFGFDVSFTNSSIYMLLASILALTYFYLAFYNRKLVPSRLQVSAEIVYNLVADMLNQNIGVKGRKFIPLVFSLFIFILFCNLLGMTPYSFTTTSHIIVTFTLAILVFLTVTIVGFVKHGLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPVSLSLRLAANMMAGHVLLKVIAGFTVSLMIYLKFLPIPLMMILIGFEIFVAILQAYIFTILSCMYLNDAINLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBT_PINKO
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKGGK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: COAX_MYCA1
Sequence: MLLAIDVRNTHTVVGLISGSKEHAKVVQQWRIRTESEITADELALTIDGLIGDDSERLTGAAALSTVPSVLHEVRLMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAFHRFQSPAIVIDFGSSICVDVVSAKGEFLGGAIAPGLQVSSDAAAARSAALRRVELARPRSVIGKNTVECMQAGAVFGFAGLVDGLVGRIREDVPGFGGDDVAIVATGHTAPLLLPELDTVSHYDQHLTLHGLRLVFERNRDAQRGRLKTAR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRG_DICDI
Sequence: MAEVDEFSAFRHENDVSIEQRIVYFINSLIVALVPVYLYHAIFFMSIDDHMIIYGSVTLFAAIVLTFAYNNIYRMKRLKLSASREHISIASKNKVGDKKKFAAAQKEVQALVTSHEAIAASIMYNNAVFLICVSIFSFIIFKNVPLVYNYIISISLGAGLTSFLSTSSKH
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
What are the official names of this protein?
Translocon-associated protein subunit gamma, TRAP-gamma, Signal sequence receptor subunit gamma, SSR-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAP-gamma family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NKX61_MESAU
Sequence: MLAVGAMEGPRQSAFLLSSPPLAALHSMAEMKTPLYPATYPPLPTGPPSSSSSSSSSSPSPPLGAHNPGGLKPPAAGGLSSLSSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASATSASAAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRAPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGTSENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGLLLHASEAEGSS
What is the function of this protein?
Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube.  Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity).  Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes.  Involved in transcriptional regulation in islet beta cells.  Binds to the insulin promoter and is involved in regulation of the insulin gene.
What are the official names of this protein?
Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOY_STRS7
Sequence: MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVEEHTDYNVEFIELLSDKHLDYEKETGVFELTEF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: RL9_PSYCK
Sequence: MQIILLQRIVNLGKLGETVDVKPGYGRNFLIPLGKALPATKANIEKFEARRAELEAEEAKEVAVAQERADALTDVNVIMRAKSGDEGKLFGSIGTRDIAEALTNSGLEVDRAEIKLPEGTLRQIGEYNVDIQLHHDVTATILVTILSEDGDNEDLDEDNAADENEDYSEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NADA_PHOPR
Sequence: MSLTYDPSETIYPFPQKPVPLSEQEKLTHVEKIKALLKEKDAVLVAHYYTDPEIQALAEETGGFVGDSLEMARFGNQHSAKTLIICGVRFMGESAKILTPEKNVLMPTLEAECSLDLGCPADKFSEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKDIIWGPDRHLGAYIQKNTGAEMLLWQGECVVHDEFSAKALRDMKALYPDAAVLVHPESPASVVALADAVGSTSQLIKAAKELPNTKLIVATDKGIFFKMQQMVPDKELVEAPTAGAGATCRSCAHCPWMAMNGLKAIESALVEGGEKHEIFVDEALRVKSLIPLNRMLNFAAELQLKVKGNA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_NEIMB
Sequence: MKVIFAGTPDFAAAALRAVAAAGFEIPLVLTQPDRPKGRGMQLTAPPVKQAALELGLRVEQPEKLRNNAEALQMLKEVEADVMVVAAYGLILPQEVLDTPKHGCLNIHASLLPRWRGAAPIQRAIEAGDAETGVCIMQMDIGLDTGDVVSEHRYAIQPTDTANEVHDALMEIGAAAVVADLQQLQSKGRLNAVKQPEEGVTYAQKLSKEEARIDWSKSAAVIERKIRAFNPVPAAWVEYQGKPMKIRRAEVVAQQGAAGEVLSCSADGLVVACGENALKITELQPAGGRRMNIAAFAAGRHIEAGAKL
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: ENGB_BART1
Sequence: MTRDSSLSGVFSRNWIFIRGVPAIRFLPPEGPPEIAFAGRSNVGKSSLINALVQQKGLARTSNTPGRTQELNYFIPDGFSGQRGDLPPFAVVDMPGYGFAAAPKNLVDAWTNLIFSYLRGRSTLKRVYLLIDSRHGIKNNDEDVLALLDKAAVSYQIVLTKSDKIKSNALEKLIMITQTKLLKHPAAYPEILATSSEKAYGLEELRAAILQTIA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SYM1_CRYNJ
Sequence: MAGLMGKYAAFLTRRPVLGNMISSAVLFGTGDVIAQQLIEKKGADHDLPRTARIVTWGGILFAPTVNLWFRTLERIPIRSRWPATFARVGLDQFGFAPVILSGFFTAMTFMEGKDFNAAKVKWHESFFPTLQANWMLFIPFQILNMGLVPLQYRLLAVNAVNIPWNAFLSLQNAKGRKAEEDPVAISKKE
What is the function of this protein?
May be involved in cellular response to stress.  Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity).
What are the official names of this protein?
Protein SYM1.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1857_AQUAE
Sequence: MQEQAQQFIFKVTDKAVEEIKKVAQENNIENPILRIRVVPGGCSGFQYAMGFDDTVEEGDHVFEYDGVKVVIDPFSMPYVNGAELDYVVDFMGGGFTIRNPNATGSCGCGSSFSCG
What are the official names of this protein?
Protein aq_1857.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PDXH_ACIC1
Sequence: MRHGTHTGSNPYAEAYVEVTAGGLAETDLAADPIEQFRRWLADAIRYNLPEPTAMVVATADADGRPSSRHVLLKSVDDGFVFFTNYRSRKGRDLSENPSASLCFPWFAIGRQVVVLGTVTKVTREETEEYFASRPRDSQCGAWSSENQSSVVPSRAWLDERYAEVAQRFAGVEHIPPPPFWGGFRVIPETVEFWQARPARMHDRLRYRRTADGERPWIIERLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: ARC_MYCBP
Sequence: MGESERSEAFGIPRDSPLSSGDAAELEQLRREAAVLREQLENAVGSHAPTRSARDIHQLEARIDSLAARNSKLMETLKEARQQLLALREEVDRLGQPPSGYGVLLATHDDDTVDVFTSGRKMRLTCSPNIDAASLKKGQTVRLNEALTVVEAGTFEAVGEISTLREILADGHRALVVGHADEERVVWLADPLIAEDLPDGLPEALNDDTRPRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVSYADIGGLSRQIEQIRDAVELPFLHKELYREYSLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAHEAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIYSKYLTEFLPVHADDLAEFDGDRSACIKAMIEKVVDRMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKNAIKSVLETGQPGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSASRAIDTESNLGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Mycobacterial proteasome ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: MRAY_WOLPM
Sequence: MILATKVFFTSFVFGFILFPYFIKLLKKISKDGQPIRSCGPESHLITKKNVPPMGGIIILISSLLPILLWAQLTPEILLLILITLFFALLGFIDDYLKLKTNHYRGLSAKTKILIQFIVALVGVFILKLYSAECFTKTSLFKGVIIDFGYLYVPFAAFVIVGSSNAVNLTDGLDGLAATQVITSFAFLGLIAYITQADMNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSVGAALGLTSVLIKREMLFAIIGIIFVIETLSVIIQISYFKYTKFKYGEGKRVFLMAPIHHHFEKKRWSENVIVMKFWIISIICSVFTITFLL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.