PharMolix/UniProtQA huggingface dataset:
Protein: MNME_EHRCR
Sequence: MTTIFALCTPWGRSGVAVIRISGEDAAKAFVHFGINSSIKPRTATFTPLYDKDGEVIDEAIVVYFVAPNSFTGEDVVEFHTHGSFAVIKMILAELGKIFVPAGPGEFSLRAFLNNKVDLTRAEAIVDLINSETEMQAKQAIRQMSGVLEKLYQNWRQQLIDILSNIEAYIDFPEEVNSSAIANIDYLLNNLQKSLESHLNDDRRGERLRQGIYVTILGEPNSGKSTLFNHLAKRDIAIVSEYAGTTRDPLEAHIDVAGYPIIIIDTAGIRESTDPVEQEGIKRAKLKAENADFKIVMLPYEKRDIFNREIMSLIDDKSICILSKADNITDQKLIPVFDFSFIPISVYCNIGIENLLNLIKQKVEKDFQFCNTDPFITSERQRKHIQNTLNIIKSVDLSLPMEIVSEDLRLSVRELGKVVGVISDDDILDNVFGKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCAL_LACDB
Sequence: MSVVGIVAEYNPFHSGHEFLMNQARLIAGDDPIIAVMSGNYVQRGEMAILDKWSRARSAIEAGADLVFELPFSYAVQAADMFATGGVDLLTRLGAKNLVFGVEDANLNFEYFGDRISKIPRQRQEFADYSQTYSTQYNQMVAREIGHEVSEPNAILGLAYAVANANLGSPLKLSPVNRVGAGHDDILQREAVVQSASAIRNLLLNGAERSELEQWLPKGEIAAFDQEKVLPNWELLFPFLKYRLESASIKELQQIYQMSEGLEYKFKAEIHLAENFADFLRRVKSKRYTYSRLRRLSLYTLLNVTEADVLNSYDHVSTMLLAYSKRGRKYLKQQRKDFEIDIVSKVDRKNAQEGTLGLQVRVDRLFEQIVGADQNFGRRPLEVN
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPN1_SCHPO
Sequence: MRPSVITVAVLFVQSTWASFAFGNPMSMRNKAHTNDLVNSKGKPLVGRFLHITDMHPDIYYEKGSTVDHYCHSYDHNSDDTPLGKSKVGYLSPGPGYECDSSPALIDKTLEWLKEHQDDVLGGIDFILWTGDNSRHDNDNHFPRTQSEILASNEDLVNKMIEAFPDVPIVSAIGNNDIYPHNIMEAGPSSMTRQLAGAWDALIPYEERHTFEKGSYYLCDVIPDKLAAISINTLYLSNKNAAVDGCPDDNLDEPGSLFMRWFKIQLEAYRLKGMKVWLLGHIPPTRGQWYEDCYTSFTDLLYEFRDIIVGQLYGHMNINHFVFLEFDKLPVDTESYGIKSAQPKYVKSLIDAQYAELPTFPENLTEEFLNGTVGNYSLATVGGSIIPEMFPTFRVYEYNISDIANQLDDREELTEITSFNWETLEEQSQSDYEIDKKKKKKKKNNKKKKKNKRKNIKPGPLGPAYVPSLFTPISFKQYFLNTSNYMDATKDTEISYELLYTSKDSPYNMPDLTVPEYMRLAKRIATCDKPEDPHQFKLQSGDQNTFRISKKKKPSICPIAYTYLWHAYIGSISDFED
What is the function of this protein?
Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
What are the official names of this protein?
Endopolyphosphatase.
What is the protein family that this protein belongs to?
Belongs to the endopolyphosphatase PPN1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein.
Protein: KHSE_MYCPA
Sequence: MVTSMLPAGLVASAVVSASSANLGPGFDSIGLALSLIDEITVETTDSGLVVQVEGEGADQVPLGPEHLVVRAVECGLRAVGVRAAGLVVRCRNAIPHSRGLGSSAAAVVGGLAAANGLVAQANCQPLSDAALIQLSSEFEGHPDNAAAAVFGGAIVSWIDRGGQHPRYAAAPLRLHPDIHLYCAIPQERSLTAETRVLLPAQVSHEDARFNVSRAALLVVALTERPDLLMAATEDVLHQPQRAPAMPASAEYLRLLRRHNVAATLSGAGPSLIALTTASALPPEVMEYGAANGFTLAEMTAGEGVRWSPGVTVVG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_SYMTH
Sequence: MRVSYNWLKDYVKVGLSPQELAERLTARGVVVENVVRANPGVEGVVVGRVVAMERHPNADTLWVCQVDVGGGRVLQILTGAQNVTVGALVPAAVPGAKLPGGVTMGVKKLRGLDSHGMLCSEAELQVGDDADGILILPPEPGLEPGMDVAEVLGLNDWIFELDLTANYAAHCQSMLGVAQEVAALVGGEVNRPSTYTPDAPGTDVRNLIAVQIDAPDLCSRYVARVVRGVKIGPSPLWLQARLRAAGMRPINNIVDIANFVMLETGQPLHTFDYAQIRGQRIIVRRARTGERFTTLDGQERVMDESVLVIADAERPVALAGVMGGEDSEVTDQTADILIESAHFDNINNRRTSLRYNLPSEASKRFTKGVDPSGCVAAADRAAQLMAELAGGTVVAGHVDVCPRPAVPPVILLRTERANALTGLKLTPERMAEHLRSLGMAVLTPADLAADLALGAPESDEEPGEDLGGHPVWTALHQVSPVPSDPVVYRTWAEAAWAEVEDAGSRLEALLGGGESDGKAAASGEGVSPGGASDGILVVVVPTRRSDVAVEVDLIEEIARCEGYDAIPLELPVLSSHRGGRSRQGEVKLAARRALAAAGLTEVLTHSLTHPRVYDMLALPEDDPNRRCLALANPMYEDRSTLRTMLLPCLLDVVRYNANRQVRDLAIFEISHVYRPVEGEQLPDEPLMIGLAMTGNLAPLGWNSPERPADFFALKGVVEHLLAELGVPDARFERSAHPSLHPGRQAALVVGGKPVGLLGELHPQVQERWELPGRVYVAELAFAPLMEAMLPQAVYRPVPRFPAVTRDVAVVVDLDLTAHRLETAIREAGGDLLEEVRLFDVYQGERVAEGRRSLAYRLVYRAADRTLTDEELEPVHNRVREALKALGAELRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTD2L_CALJA
Sequence: MTVPARGFLLLRGRLGRVPALGRSTAPPVRAPGGPRSAFRGFRSSGVRHEAVIISGTEMAKHIQKEIKQGVESWISLGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERMICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIITRTGIQTFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKTHTQLADVIIVAAGIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY
What is the function of this protein?
Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities.
What are the official names of this protein?
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial, NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein, MTHFD2-like.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ERF5_NICSY
Sequence: MASPQENSTTLDLIRQHLLDDNVFLEHYCSETETTTLIYSQSSSSSESLDQSFSFEPTLNYATTAQSSNLEVSTFFNNSKTEFDSFEFGTIPNVSAARSSSLKQTSFKERKPSLNIAIPVKQEVVQKVELAPTEKKHYRGVRQRPWGKFAAEIRDPNRKGTRVWLGTFDTAIEAAKAYDRAAYKLRGSKAIVNFPLEVANFKQEFNNEIRPLVNSSRKRVRETVNEEQLVINKEMKIEEERVPTAPLTPSSWSAIWDSGDGKGIFEVPPLSPFGAYSQLVMI
What is the function of this protein?
Transcription factor that binds to the GCC-box pathogenesis-related promoter element.  Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.  Probably acts as a transcriptional activator (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor 5, Ethylene-responsive element-binding factor 4, EREBP-4, Ethylene-responsive element-binding factor 5 homolog, NsERF4.
What is the protein family that this protein belongs to?
Belongs to the ethylene-response factor family. Class 3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: COXM1_HUMAN
Sequence: MALDPADQHLRHVEKDVLIPKIMREKAKERCSEQVQDFTKCCKNSGVLMVVKCRKENSALKECLTAYYNDPAFYEECKMEYLKEREEFRKTGIPTKKRLQKLPTSM
What is the function of this protein?
Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.
What are the official names of this protein?
COX assembly mitochondrial protein homolog, Cmc1p.
What is the protein family that this protein belongs to?
Belongs to the CMC family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Colocalizes with MT-CO1.
Protein: HTPG_XANC5
Sequence: MTVETDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPELLEGSGELRIRVDYDKDARTVTIDDNGIGMSREEAVSHLGTIAKSGTADFLKHLSGDQKKDANLIGQFGVGFYSAFIVADQVDVYSRRAGLPASEGVHWSSRGEGEFEIASVDKPERGTRIVLHLKEGEESFADGWTLRGILKKYSDHIGLPIEMRKEHYGEAADKPAEPEWEAVNRASALWTRPKSEIKDEEYQEFYKHIAHDAGNPLAWSHNKVEGKLEYTSLLFVPGRAPFDLYHRDSAKGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSSDLSLNVSREILQSGPVVDSMKSALTKRSLDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREKIAGLLRFSSTHDTTGAQSVGLADYVSRLAEGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTEFDGKSFVDVARGDLDLGKLDSEEDKKAQEDLAKSKEGLASRIKAALGDDVAEVRVSHRLTDSPAILAIGQGDLGLQMRQLLEASGQAVPESKPVFEFNPTHPLIEKLDAEQDMDRFGDLSRVLFDQAALAAGDSLKDPAAYVRRLNKLLLELSV
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EARP_NEIMH
Sequence: MNTPPFVCWIFCKVIDNFGDIGVSWRLARVLHRELGWQVHLWTDDVSALRALCPDLPDVPCVHQDIHVRTWHSDAADIDTAPVPDVVIETFACDLPENVLHIIRRHKPLWLNWEYLSAEESNERLHLMPSPQEGVQKYFWFMGFSEKSGGLIRERDYCEAVRFDTEALRERLMLPEKNASEWLLFGYRSDVWAKWLEMWRQAGSPMTLLLAGTQIIDSLKQSGVIPQDALQNDGDVFQTASVRLVKIPFVPQQDFDQLLHLADCAVIRGEDSFVRAQLAGKPFFWHIYPQDENVHLDKLHAFWDKAHGFYTPETVSAHRRLSDDLNGGEALSATQRLECWQTLQQHQNGWRQGAEDWSRYLFGQPSAPEKLAAFVSKHQKIR
What is the function of this protein?
Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.
What are the official names of this protein?
Protein-arginine rhamnosyltransferase, EF-P arginine rhamnosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 104 family.
Protein: TRMD_FRACC
Sequence: MRADIVTIFPAYLEPLRLSLVGRAQEHGTLQIHTHDLRMWTTDVHRTVDDAPYGGGPGMVMRPEPWDAALSQITARVADSRPRVVVPTPAGTPFTQRHAEELAREPWLVFCCGRYEGIDARVIETWADDEISIGDYVLAGGEAATLVILEAVTRLLPGVLGNSASVADDSFSDGLLEGPVYTRPPVWRGTEVPPVLRSGDHEAIARWRRSQALRRTLLRRPDLLEHREFAEADRVVLAAAAAEAAGRMLPAPTEGTGLIHHRDVEGPGEG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDM5D_MOUSE
Sequence: MKPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERKILDLYSLNKIVMEEGGYEAICKDRRWARVAQRLNYPSGKNIGSLLRSHYERIIYPYEIFQSGANLVQCNTDPFDSEERDKEYKPHSIPLRQSVQPSKFSCYSRRGKRLQPEPEPTEEDIEKNPELKKLQIYGAGPKMIGLGLKAKEKTLRKKDSKQPDKEEVTCPATIVVKGEASEFGKVTSAFSDKNLNHSFEPCMKMTMQLRNNHSSTQFMNSYVCRICSRGDEVDKFLLCDGCSDNYHIFCLLPPLSEVPKGVWRCPKCILAECKSPPEAFGFEQATQEYTLQSFGEMADSFKADYFNMPVHMVPTEVVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVNNSKWDLSPEEKEYAACGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEDVMKRLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPVGRQCIEHYRRLRRYCVFSHEELICKMAAFPEKLDLNLAVAVHKEMFIMVQEERRLRKTLLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDSLVCLSHINDLCKCSRNRQYLRYRYTLDELPAMLQKLKIRAESFDNWANKVQAALEVEDGRKRSFEELRALESEARDRRFPNSELLQRLKKCLTEAEACISQVLGLISNSEDRLQTPQITLTELQLLLKQMGTLPCTMHQIDEVKDVLQQVESYQIETREALTSLPYSLEILQSLMEKGQQLRVEVPEAHQLEELLEQAQWLDQVKQALAPSGQRHSLVIMKKLLVMGTKVASSPSVNKARAELQELLTIAECWEEKAHFCLKASQKHSPATLEVIIREAENIPVYLPNIQSLKEALTKAQAWIADVNEIQNGDHYPCLDDLEGLVAVGRDLPVELEELRQLENQVLTAHSWKEKASKTFLKKNSCYTLLEVLCPCADAGSVSTKRSRWIEKEMGLYKYDTELLGLSAQDLRDPGSVIMAFKEGEEKEKEGILHLRHINSAKPSPMSSSMNASATSICICGQVCAGVESLQCDLCHDWFHGQCVTVPHLLSSVRASHTSSQLLAWWEWDTKFLCPLCMRSRRPRLETILSLLVGLQRLSVRLPEGEALQCLTERAIGWQGRARQALASEDVTALLKQLEKSRQQLQDELRHKKPPTLPSGFAFDCLTENSGKDILKEEEELVLNEERIKSSEKIVPKESSCKGDKELLPSLLSQLTGPVLELPEATRAPLEELMMEGDLLEVTLDENYSIWQLLQAGQNPNLERIHTLLELEKPENPGNWSEEQTPERRRQRRQKVVLSRKGEDFTQKELESKRVKSSRIKPKEEKFQKPILGDNVLYTHHTEHTNILKEHINSVQGKDPSPSSSFPSLTPLLHLSYFHQQKL
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'.  Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'.  May play a role in spermatogenesis.  Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8.  Suppresses prostate cancer cell invasion.  Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 5D, Histocompatibility Y antigen, H-Y, Histone demethylase JARID1D, Jumonji/ARID domain-containing protein 1D, Protein SmcY, [histone H3]-trimethyl-L-lysine(4) demethylase 5D.
What is the protein family that this protein belongs to?
Belongs to the JARID1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MCSB_BACCN
Sequence: MSLDRIMNEAISPWMKGDGPDSDIVLSTRIRLARNLKNYHFPIMQTAEEANQITELFQQKLVNKTMRDFGSFELLKMNELTPLQRRVLVEKHLISPNLAETEFGACILSESEHISVMLNEEDHVRIQCLFPGLQLSEALQSANKIDNVFEEVVEYAFDEELGYVTSCPTNVGTGLRASVMIHLPALVLTKRINRIIQAIQQLGLVVRGIYGEGSEALGNIFQVSNQMTLGKSEEDIIADLTSVIHQLIQQEKAARELIVKNSSIELEDKVYRSYGILAHSRLIQSAEAATCLSDVRLGIDLGYIKDVSRNILTELMVLTQPGILQQYAGGQLGPEERDYRRAALIRERLRIEENEA
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in a large number of proteins.  Is part of the bacterial stress response system.  Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: MSCL_BURTA
Sequence: MSIIKEFKEFAVKGNVMDLAIGVIIGGAFSKIVDSVVKDLIMPVIGVLTGGLDFSNKFVLLGQIPASFKGNPESFKDLQAAGVATFGYGSFITVLINFIILAFIIFLMVKFINKLRKPEEAAPAATPEDVLLLREIRDSLKQR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXS_PROMT
Sequence: MRLSQLSHPNELHGLAISELEDVACQIRERHLQVVSTSGGHLGPGLGVVELTIALYQTLDLDVDKVIWDVGHQAYPHKLLTGRYNRFDSLRQQKGVAGYLKRTESKFDHFGAGHASTSISAALGMAIARDRKGEDYKCVAVIGDGALTGGMALEAINHAGHLPKTPLLVVLNDNDMSISPPVGALSTYLNRMRHSPPVQFISDSVQESVKNLPFMGDAIQEEFKSLTGSVRRLAVPSVGAVFEELGFTYMGPVDGHDIAELTRTFNAAHKVGGPVMVHVATTKGKGYPYAEADQVGYHAQSSFDLTTGKSIPSKTPKPPSFSKVFGQTLVKLCEQDSKIVGITAAMAEGTALNLLQKAIPDQYVDVGIAEQHAVTLAGGMACEGIKPVVAIYSTFLQRAYDQLIHDIGIQNLPVTFVLDRAGIVGADGPTHQGQYDISYLRCIPNFTVMAPKDESELQQMLVTCINHNGPSALRIPRGSGEGAALMEEGWESLEIGKAETLEEGENLLIIGYGSMVFPAIRTAAILKEFGVNSTVINARFIRPLDEDTIHEAAKRIGKVVTMEEGTLLGGFGSAVVESFNDNDIFVPTLRIGIPDKLVDHATPQQSKESLGLTPEMMADQIRNKFNFN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: T170A_CHICK
Sequence: MEGSEAGGGGLLQQILSLRLVPRVGNGTTYSSPLSTFPEMWYGVFLWALVSSLSFHVPAALLALFTLRHHKYGRFMSVSLLLMGIVGPITAGILTSAAIAGVYRAAGKKMIPFEALIFEVGQTFCVVVVSFLRILATL
What is the function of this protein?
May regulate membrane morphogenesis in the endoplasmic reticulum (ER) by promoting ER sheet formation at the expense of ER tubules.
What are the official names of this protein?
Transmembrane protein 170A.
What is the protein family that this protein belongs to?
Belongs to the TMEM170 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope.
Protein: TPMT_VIBCM
Sequence: MRDPEFWHNKWAANQIGFHLEDVNPLLIRFWSDLAPKRSEKVLVPLCGKSEDLIWLANQHDSVQGVELSQIAVRSFFAEHFYTPTVTRLNAQHELYQFDELTLFTGDFFTAPVESVDLVYDRAALVALPEEMRAEYAQRVLQLLKPGGRILLVSMDYVQTELSGPPFSVPEAEIRTLFMGCEVRRVYQDTSIDPHLNKRTQAGLSRFAEEVWVIEKSE
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_MYCMS
Sequence: MEKTLKGIVLNSFDFQDYDKIITIYSNLYGKISLVCLGVNKIKSKNKYGINYLSYSNFEIFKSKNKFNLSKLKRSELINSFNHISTDFNLYLYANIITSLVLSLDEQIKNYNLYKTLKLSISIINNKSDFGLKVCVLFMFYFLKIIGNQIDLSKCGFCNSKINPIIAISFTNYCSSCKFCYFDDCILIDNQLSNFINSIFKNDFITNLSQEISTNNLNILTRFILNYYQDIVGTYTTSMYLLSTLIRFN
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RLMH_BACHK
Sequence: MNISIISIGKLKEKYLKQGIAEYLKRLSAYAKVEVIELPDEKAPENLSEAEMLIVKEKEGIRILDKISDDTHVIALAIEGKQKSSEEFAVSLDRLATYGKSKVAFVIGGSLGLSSEVMKRSNESLSFSKMTLPHQLMRLVLLEQVYRSFRINRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTR_BACAA
Sequence: MPTPSMEDYIEQIYLLIDEKGYARVSDIAEALSVHPSSVTKMVQKLDKDEYLIYEKYRGLVLTSKGKKIGERLVYRHELLEQFMRIIGVDESKIYNDVEGIEHHLSWEAIDRIGDLVQYFEQDEVRVETLRGVQKANEEKSN
What is the function of this protein?
Central regulator of manganese homeostasis.
What are the official names of this protein?
HTH-type transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLD_GEOKA
Sequence: MKTIRLTTAQALVKFLNQQYVEFDGHIQKFVKGIFTIFGHGNVLGLGQALEEDPGELEVYQGRNEQGMAHAAIAFAKQKHRRQIMACTSSVGPGAANMVTAAATASANHIPVLLLPGDTFATRQPDPVLQQIEHWHDLTVSTNDAFRAVSKYWDRISRPEQLMSAMIQAMRVLTDPANTGAVTIALPQDVQGEAYDFPESFFQKRIHRIERRVPAKAAIHEAVELIRRKKKPIIICGGGVRYSEAAEELKQFAEKFHIPYGETQAGKSAVESAHPYNLGGIGVTGNLAANIIAKEADLVIGIGTRYTDFTTGSKQLFQHPEVEFLTINVSVFDACKLDAVRVVADAKLALLALTEELEKIGYRSGYTNEIDIAKKAWEEELNRLHHVRYRQSGFQPEVAGHLDEVLTEYSEFFDSSLTQTEVIGAINEWIDDDAIIIGAAGSLPGDLQRMWVARRPNTYHMEYGYSCMGYEIAGALGVKMAEPDKEVYAMVGDGSYLMLHSELVTSIQEKKKINVLLFDNGGFGCINNLQMGHGMGSFATEFRYRNEETGRLDGSLIPIDFAQSAAGYGVKTYKVHTLEQLKEALEDAKQQSVSTLIDIKVLPKTMTHDYESWWHVGVAEVSRNPKIAEAYKRKEQQLQRARKY
What is the function of this protein?
Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
What are the official names of this protein?
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, THcHDO hydrolase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: DLL3_MOUSE
Sequence: MVSLQVSPLSQTLILAFLLPQALPAGVFELQIHSFGPGPGLGTPRSPCNARGPCRLFFRVCLKPGVSQEATESLCALGAALSTSVPVYTEHPGESAAALPLPDGLVRVPFRDAWPGTFSLVIETWREQLGEHAGGPAWNLLARVVGRRRLAAGGPWARDVQRTGTWELHFSYRARCEPPAVGAACARLCRSRSAPSRCGPGLRPCTPFPDECEAPSVCRPGCSPEHGYCEEPDECRCLEGWTGPLCTVPVSTSSCLNSRVPGPASTGCLLPGPGPCDGNPCANGGSCSETSGSFECACPRGFYGLRCEVSGVTCADGPCFNGGLCVGGEDPDSAYVCHCPPGFQGSNCEKRVDRCSLQPCQNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGSRRCSCALGFGGRDCRERADPCASRPCAHGGRCYAHFSGLVCACAPGYMGVRCEFAVRPDGADAVPAAPRGLRQADPQRFLLPPALGLLVAAGLAGAALLVIHVRRRGPGQDTGTRLLSGTREPSVHTLPDALNNLRLQDGAGDGPSSSADWNHPEDGDSRSIYVIPAPSIYAREDWLIQVLF
What is the function of this protein?
Inhibits primary neurogenesis.  May be required to divert neurons along a specific differentiation pathway.  Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
What are the official names of this protein?
Delta-like protein 3, Drosophila Delta homolog 3, Delta3, M-Delta-3.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LIPB_NITHX
Sequence: MVNNRQTLDLKLFPASPGELVDWQLSDTPVPYPEAVAAMEARAAAIASGEASELVWLLEHPPLYTSGTSGRETDLLQARFPLFSTGRGGQVTYHGPGQRVAYVMLDLKRRRPDVRAFVAGLEEWIIRTLDTFDIKGERREDRVGVWVARPDKGPGHEDKIAAIGVRLRRWVSFHGISLNVDPDLSHFDAIVPCGITDARYGVTSLADLGLRVRLSDVDAALRRAFGEVFGPSELRLPETTA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_PROMT
Sequence: MSTAIAQQKIRIRLKAFDRRMLDLSCDKIIETADTTAASAIGPIPLPTKRKIYCVLRSPHVDKDSREHFETRTHRRIIDIYSPSAKTIDALMKLDLPSGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PHS_PSEFS
Sequence: MTTLNQAHCEACRADAPQVSDEELPVLLKQIPDWNIEVRDGVMQLEKVFLFKNFKFALAFTNAMGEISEAEGHHPGLLTEWGKVTVTWWSHSIKGLHRNDFIMAARTDEVAKDAEGRK
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: HIS2_NITOC
Sequence: MNNTLERLATLLEERKNADPQHSYVAHLYQAGQDKILKKLGEEAIETILAAKSRESDAIIYETADLWFHSLVMLAESGLRPEQVLSELERRFGLSGLEEKANRG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA1G_CONCN
Sequence: LTTTVVSFPSDSASDGRDNEAKDERSDMYELKRNGRCCHPACGKYFKCGR
What are the official names of this protein?
Alpha-conotoxin CnIG.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAA_COLP3
Sequence: MDHSPWQRCLSVLQEELPAQQFSMWIRPLQCVINDNVMTLYAPNRFVLDWVRDKYVNRINELLTINESNNPLLLRFDVGSKPTIDNSVTNSPVSRNTGGNESLFAKATSAPKVAEPESNIPKKTNVRLNYTFENFVEGKSNQLARAAASQVADNPGTAYNPLFIYGGTGLGKTHLLHAVGNGILLNKPNAKIAYMHSERFVQDMVRALQNNAMEKFKQYYRSVDALLIDDIQFFAGKERTQEEFFHTFNALLEGNQQVILTSDRYPKEINGVDDRLKSRFGWGLTLAIEPPELETRVAILKRKAQESQINLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQDKLVTIDNIQRTVAEYYKIKIADLLSKRRNRSVARPRQIAMALSKELTNHSLPEIGDAFGGRDHTTVLHACRKVKSLREETHDIKEDYSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.