PharMolix/UniProtQA huggingface dataset:
Protein: MIAA_WOLWR
Sequence: MKNNIVIITGITASGKSELCDNLIEKYGNISIINCDSKQVYEEIPIITAQPPKQEVFYKLYGYVSAKENYSVGLWLEDLEKEVNHALENAQIPIITGGSGLYISSLIKGLSSMPQISQKVRKNVSELRKNLSKEEFYKLALSKDPRIQGKVFMNDSHRLSRALEVITETGKSIFVWQENRQPPLFNNFKIYTILPKREDVYRKINSRFITMIENGAIDEVKKLLSMNLAPHLPAMKAHGVPEIIKYLKGEITLDEAIQIAQTNTRHYAKRQYTWFKKQFLNAEVIDCANKLKIF
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL18E_SACS2
Sequence: MKVTGSTNITVRKLIRNLEKSKKPLWRKVAEELSIPSRKRPYINLYKINEHTKPNDIVVVPGKVLGIGKLDHEVTVIALDFSKSAIEKIRASGGQAMSIYKALETFKDFKGRSVRLMKQ
What are the official names of this protein?
50S ribosomal protein L18e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: BPT_STRM5
Sequence: MAIHGDRDDELRLFQTGEHPCGYWSDRVARDLVLDPHDRRLGGLYPLALSWGFRRSGDLVYRPHCAHCQACVAVRIPVARFAPDRSQRRCAARNEDLEVRITAATARDDLFALYHRYLTHRHANGGMDDHGPHEFEQFLIGSWSHTRFMEMRLPGHDGQPSQLLGVAVTDVTEHGLSAVYTFFDPDHAARGLGTFAILQQIEWARREGLPHVYLGYWIRGHQKMDYKRRYRPLEAYDGRRWHDFDDELDGR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_CHLAD
Sequence: MKESLPITLRPNEPMSRHTSWRVGGPAQYYAEPTTPDEAMVLAAWAMTHRLPLIWVGRGTNLLVRDEGFAGVIASYRGQRWALHEHGETAELWVEAGTPMAGTARRLAAMGWAGLEWAEGLPGAIGGAIVGNAGCYGGDTASVLIDAELLLNGSERVVWPVTELGYAYRESILKRPGADGVPPLVLAGRFRLHRADPKVLMARIGAIAAERKRKTPAGSSCGSVFKNPPGDSAGRLIEAAGLKGTRVGDAEISPIHANYIVNRGQARAADILTLIELARTTVAEQFGVMLQLEVRVI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_CLOBA
Sequence: MGLLSAVFGTYSEREVKRIRPIVSKINELDEVMQKLSDDELKAKTVEFKERLNNGETVDDILPEAFAVVREASKRVLNMKHYDEQLIGGVVLHQGRIAEMKTGEGKTLVATLPAYLNGLTGKGVHIITVNDYLAKRDAEQMGELYGFLGLTTGVIVHELTNEQRREAYNSDITYGTNNEFGFDYLRDNMVIYKEERVQRKLNFTIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYFVKTLVKEKDYTIDEKANAVMLTDEGFHKAEQTFKVENYADAENVELQHYVTQALKANYAMRRDKDYMVKDGEVIIVDEFTGRLMEGRRYSDGLHQAIEAKENVKIARESKTLATITFQNYFRMYEKLSGMTGTALTEENEFREIYGLDVIVVPTHKPVVRIDNPDLVFKSEKGKIMAVVDEIAKAHEVGQPVLVGTVSIEKSELISSMLKKKGVPHQVLNAKFHEQEAEIITHAGEKGMVTIATNMAGRGTDIKLGEGVLEIGGLKIIGTERHESRRIDNQLRGRSGRQGDSGESTFFISLEDDLMRIFGSEKIQGVVEKLGLEEDEAIESKLVSKSIENAQKKVEGNNFDIRKTLLGYDDVMNKQREVIYKQRSEVLEGEDVKEEILHMLRDVISDAVNTHIKEDAEDYRESFLYLISYLNDICIPTNEVNLPALADMSKEEIVDHLYDVAVKSYENKEAEFTPERLREIERVVLLRSVDTKWMDHINNMDNLKQGIGLRAFKQVDPVQAYQMEGSAMFEEMIDSIKNETVKMLFHVKVERAPERVRVAQETNAVHGDKPSAPVGPVRNLNKFGRNDVCPCGSGKKFKNCCGREA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: ENO_RHOCS
Sequence: MSAIIDIHAREILDSRGNPTVEVEVRLESGAFGRAAVPSGASTGAHEAVELRDGDKARYGGKGVLRAVESVNGEIFDTLSGLEATEQVAIDSIMIELDGTPNKNRLGANAILGVSLAVAKAAADELDQPLYRYVGGTNARTLPVPMMNIINGGAHADNPIDIQEFMVMPVGAETCADSIRMGAEIFHALKKKLKDAGHNTAVGDEGGFAPNLKSTDEALGFIMKAVEAAGYRPGEDVLLALDAASTEFYRNGRYELAGEGKSLDAAGMVAYWQDLVGRYPIVSVEDGMAEDDWDGWKALTDAIGGSVQLVGDDLFVTNPTRLSEGISRGIANSILVKVNQIGSLTETLEAVRIAQSNGYTAVMSHRSGETEDSTIADLAVATNCGQIKTGSLSRSDRIAKYNQLIRIEEGLGRARIFPGRAALKRG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ARGJ_METCA
Sequence: MAASPEDRNLSDIRLCPIAGIRLGTAAAAIKHVGRDDVLLIEMAEGSACAAVFTQNAFCAAPVTVAREHLRQAPRWLLVNSGNANAGTGTRGLADARASCEAVAALVGGRADRVMPFSTGVIGEYLPLDKIRAALPKAFEALSEDGWEAAARAIMTTDTRPKKAVRRIEIAGRPVVVSGIAKGAGMIHPNMATMLAFVATDARIGAGLLQSVLERAVNRSFNCITVDGDTSTNDACVLMASQRSEAPLIEPGSAHVEAFQSAVDAVLAELAEAIVRDGEGATKFIRILVEEAASEDEARLVGKTIAHSPLVKTAFFASDPNWGRILAAVGRAGCKDLDISRVAIWLDEVRIVAAGARDREYTEARGITVMRRPEITVRVSLGRGQASARVMTCDLSLDYVRINAEYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCS1_NOSS1
Sequence: MTTDNSAPTASPWWSLPGKFLRREFLPVLTDLRLAIALLLIIALFSISGTVIEQGQSPAFYQSNYPEHPALFGFLTWKVIQVVGLDHVYRTWWFLSLLVLFGTSLTACTFTRQLPALKTAQRWKYYEEPRQFQKLALSAELDAGSVNSLSQILQNRRYKIFQEKDDILYARKGIVGRIGPIIVHIGIVTILLGSIWGAMTGFIAQEMVPSGETFQVKNIIDAGPLAAGQFPQDWSVRVNRFWIDYTPKGGIDQFYSDMSVLDNQGQEVDHKKIFVNQPLRYHGVTFYQTDWGISGVRVRLNKSPIFQLPMALLNTNGQGRIWGTWIPTKPDLSEGVSLLAKDLQGMVLIYDAQGKLVDTVRAGMSTQVNGVTLKVLDVVGSTGLQIKADPGIPIVYTGFGILMLGVVMSYFSHSQIWALQKGDRLYVGGKTNRAQVAFEQEVLDILERLNSQSATVINQQS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: DNAK_GUITH
Sequence: MGKVVGIDLGTTNSVVAVMEGGKPAVIQNAEGFRTTPSVVAYTKTGDRLVGQIAKRQAVINPDNTFYSVKRFIGRRSEEVSEELKQVSYIVKTDSNGNIKLDCPSLKKEFASEEISAEVLRKLVDDASKYLGESVKQAVITVPAYFNDSQRQATKDAGRIAGLEVLRIINEPTAASLAYGLDKKNNETILVFDLGGGTFDVSVLEVGDGVFEVLSTSGDTHLGGDDFDDKIVQWLLKEFETEHSINLKSDRQALQRLTEASEKAKIELSNLSQTEINLPFLTATETGPKHLERSITRAKFEELCSDLINRVKIPVENALKDAKLDSSKIDEVVLVGGSTRIPAIQELVKRILNKTPNQTVNPDEVVAIGAAVQAGVLAGEVKDILLLDVTPLSLGVETLGGVTTRIIPRNTTIPTKKSEVFSTAVDNQPNVEIHVLQGEREFAKDNKSLGTFRLDGILPAPRGVPQIEVTFDIDANGILSVTAKDKGTGKEQSITITGASTLPSDEVERMVNEAQNSAKEDKEKRDKIDLKNQSDSLCYQSEKQLKELEGKIDDTNKNKISSMISELRNAINNENYDEMRDLNSKLQTALMDLGKSVYEKTSKEQTSTSSPTNSNDSVIDADFSETK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: QUEC_SYNSC
Sequence: MSQRTAIALLSGGLDSATAAALALEQGDRVIGLSFDYGQRHLRELDAAAAVAQQLGLAEHHCISVNLASWGGSALTDASISIPTDGVEEGRIPPTYVPGRNTVFISVGLSLAEARGAERLVLGVNAVDYSGYPDCRPDYLNAFQTLADLASKAGREGHGAQLWAPLVQWSKVRIVEEALRLGVPIETTWSCYSGGTHPCGVCDSCRIRDAALREAGRPDLCSSTAA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RHTB_SALTI
Sequence: MTFEWWFAYLLTSTLLSLSPGSGAINTMTTSINHGYRGAAASIAGLQTGLGIHIVLVGVGLGTLFSRSLIAFEILKWAGAAYLIWLGIQQWRAAGAIDLHTLAQTQSRGRLFKRAIFVNLTNPKSIVFLAALFPQFIMPQQPQLAQYLILGVTTIVVDMIVMTGYATLAQRIAAWIKGPKQMKALNKAFGSLFMLVGALLASARHA
What is the function of this protein?
Conducts the efflux of homoserine and homoserine lactone.
What are the official names of this protein?
Homoserine/homoserine lactone efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPX_FUSNN
Sequence: MSKKMDRCSFCGRTEREVTQLFQGPGDVFICDSCVESCHSLLRDDMYSLAREYENLRDGKSSNNKNYKGKIELLKPVEIKAKLDEYVVGQDEAKKVLSVAVYNHYKRILNNGQDDDGVELQKSNVLLVGPTGSGKTLLAQTLAKILNVPFAIADATTLTEAGYVGDDVENVLVRLIQACNYDIPNAERGIIYIDEFDKIARKSENVSITRDVSGEGVQQALLKIIEGTKSQVPPEGGRKHPNQELIEIDTKNILFIVGGAFEGLEKIIKARTNKKVIGFGAEVQKQDNMGTEGEFFKKVLPEDLMKQGIIPELVGRLPVITTLDNLDEQTLINILTKPKNAIVKQYQKLCKLEGVKLEFTQEALTEIAKRALKRKMGARGLRAIIEHTMLDIMFELPSNNNIKEITITKDTIDNYKKAEIEYK
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SYL_MYCBO
Sequence: MTESPTAGPGGVPRADDADSDVPRYRYTAELAARLERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRRSFSTTDVDFYRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKLTAGERADVIDEYRLVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAASWPAGVNPLWTYGGGTPGEAIAAYRRAIAAKSDLERQESREKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFDPDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPGGVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYVPAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTTSLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGATPRKVIVVAGRLVNLVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_POLSI
Sequence: SVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFQAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YJGD_BACSU
Sequence: MAKAIKRIQKIEVTEEDQRKRDLREIEDALIDHKEAILETLHMLGHMNERGVLPLLRGLFGQGDKVLDILVKKADTEETANTLKNLLLLFGTLGMLDVKQLEPLILKVNAGVASAVEQKNSEEKTGYFDIIRSLKDPEINKSITLLFSFLKGMGQDTKELERTTQPPEHQKHHQEPREKRGMNKRD
What are the official names of this protein?
Uncharacterized protein YjgD.
Protein: SURE_XANOM
Sequence: MRVLVSNDDGVDAPGIQILAEALRHGGHEVMVVAPDRDRSGASNSLTLDVPIRTRRIDAQTCAVAGTPTDCVHLALTGMLDCDPDIVVSGINNSANLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTHNHQAHHYDTAARAAVEIVARLKADPLPADTILNVNVPDLAWSDVLGFEVTRLGNRHRSEPCVPQRDPRGRTVYWIGPAGPEQDAGAGTDFHAVRTGHISITPIHVDLTRYQALETVAGWVGGLTAALDGPA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_NEIMB
Sequence: MSDFFHSDVLSVSELNAFAKSLLENHLAGLWIAGEVSNLTRAASGHYYFSLKDSRAQVRCAMFKGAAVRLAKPLKEGDHIEVSGKISIYEARGEFQITVNEVRLKGLGQLYEAYERLKAQLQAEGAFAAERKKPLPVRPQCIGIVTSLAAAALRDVVTTLKRRAPEIPVIVYPTPVQGAGSELQIAQAIKTASQRAECDVLIVCRGGGSIEDLWAFNEEPVVRAIESCTVPVVSGVGHETDFTLADFVADMRAPTPTGAAELVSPNRQESLHRLAQAQCRLKTVLEQRYFDASQKLDWLARQIRHPRQKLDEQRASIGKLAQTLSYSMTQNVRTHTARFERQTQALKHCRPDVSVCKKNIDRFQTALSHAFHQLLTHRRQSLTAQAALLEAVSPQHILERGFSVVKNTRGQVIRNADVLKQGQKLHIIFADGETDVRVSKEQGQQDLFDCI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H4_PONAB
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GERXB_BACAN
Sequence: MVNFFQIALVLIGSTGIINHVIIIPMLLDHSGRDSWISIIILSLVYIIWIPCVFIVHKYTREEHLFSWLMRNYGGFITYPLLSIIVLYLIILGTVTLKETLTFFSFYLPETPRILLGVLLSIICFYNIQRGVQSIALTTGILLPVVFLLGFFVMIANFPHKDYSLLKPIMEHGMDPVIKGMIYPAAGFVELIFILFLQHHIGSKIKLSQLIIVGIILAGITLGPTIAAIVEFGPFVAANQRYPTFEEWRLVSIGKYIEHLDFLSVYQWLVGVFIRISLVIFLIPDVLQVTKQKARNQIISILLICMVIICILPISDASFYWFLSHVFLPISAIGLFLFSMLLLVFVWVSKNKKRA
What is the function of this protein?
May allow B. anthracis to germinate within phagocytic cells and therefore involved in virulence.
What are the official names of this protein?
Spore germination protein XB.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNPA_GEOSM
Sequence: MTSSNFPKAERLLRRPEFLQFNEGASKLHTQHFLVLLKLKEGTGTRVGFTVSKKVGNAVVRNSIKRRLREFYRQNKSLFILADINIVAKKGADVLDFQQISTELAAAFGRLRKKYA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: GRIA2_PONAB
Sequence: MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYYAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIAGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLYPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI
What is the function of this protein?
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse.  The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.  In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate (By similarity).  Through complex formation with NSG1, GRIP1 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).
What are the official names of this protein?
Glutamate receptor 2, GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Postsynaptic density membrane; Multi-pass membrane protein. Note=Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression (By similarity). Displays a somatodendritic localization and is excluded from axons in neurons (By similarity).
Protein: Y842_ARCFU
Sequence: MILLVALLSGLGLFLGVLAGLAGLILGSIFVVSPFVLLSAGGLALQVLNFLLLFISTIAGGFLGLLSFI
What are the official names of this protein?
Uncharacterized protein AF_0842.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPIL4_HUMAN
Sequence: MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTGRGGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLDGVHTVFGEVTEGMDIIKKINETFVDKDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSPEPTREQLDSGRIGADEEIDDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADIKPPENVLFVCKLNPVTTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFKMDNVLIDDRRIHVDFSQSVAKVKWKGKGGKYTKSDFKEYEKEQDKPPNLVLKDKVKPKQDTKYDLILDEQAEDSKSSHSHTSKKHKKKTHHCSEEKEDEDYMPIKNTNQDIYREMGFGHYEEEESCWEKQKSEKRDRTQNRSRSRSRERDGHYSNSHKSKYQTDLYERERSKKRDRSRSPKKSKDKEKSKYR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 4, PPIase, Cyclophilin-like protein PPIL4, Rotamase PPIL4.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAA_FRUSA
Sequence: ALGDQLLSVFVDHTLVDEVA
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MINE_ACIBT
Sequence: MAGFWSKLFSSEEKPSSAQTAKDRLKVIVASEQGLGRRLSQDKIDQMKKEIMQVVSRYVSGVGEQHIQMQVRSEANIEMLEMNINLPEER
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: DPOL_WHV3
Sequence: MHPFSRLFRNIQSLGEEEVQELLGPPEDALPLLAGEDLNHRVADALNLHLPTADLQWVHKTNAITGLYSNQAAQFNPHWIQPEFPELHLHNDLIQKLQQYFGPLTINEKRKLQLNFPARFFPKATKYFPLIKGIKNNYPNFALEHFFATANYLWTLWEAGILYLRKNQTTLTFKGKPYSWEHRQLVQHNGQQHKSHLQSRQNSSMVACSGHLLHNHLPSEPVSVSTRNLSNNISDKSQKSTRTGLCSYKQVQTDRLEHLARISCGSKITIGQQGSSPKTSYKSISSNFRNQTWAYNSSRNSGHTTWFSSASNSNKSRSREKAYSSNSTSQRYSPPLNYEKSDFSSPGVRGRITRLDNNGTLPQCLWRSFYNTKPCGSYCIHHIVSSLDDWGPCTVTGDVTIKSPRTPRRITGGVFLVDKNPNNSSESRLVVDFSQFSRGHTRVHWPKFAVPNLQTLANLLSTNLQWLSLDVSAAFYHIPISPAAVPHLLVGSPGLERFNTCMSSSTHNGNDSQLQTMHALCTRHVYSSLLLLFKTYGRKLHLLAHPFIMGFRKLPMGVGLSPFLLAQFTSAIASMVRRNFPHCVVFAYMDDLVLGARTSEHLTAIYSHICSVFLDLGIHLNVNKTKWWGNHLHFMGYVITSSGVLPQDKHVKKLSRYLRSVPVNQPLDYKICERLTGILNYVAPFTLCGYAALMPLYHAIASRTAFIFSSLYKSWLLSLYEELWPVVRQRGVVCTVFADATPTGWGIATTCQLLSGTFAFPLPIATAELIAACLARCWTGARLLGTDNSVVLSGKLTSFPWLLACVANWILRGTSFCYVPSALNPADLPSRGLLPVLRPLPRLRLRPQTSRISLWAASPPVSPRRPVRVAWSSPVQTCEPWIPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.