PharMolix/UniProtQA huggingface dataset:
Protein: DTD_BURTA
Sequence: MIALIQRVKRADVRVGERVTGEIGPGLLALVCAERGDTEAAADKLLAKVLGYRVFSDAAGKMNLPVSNLDGAGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGERLFDYFVRRARERHPIVATGEFGADMQVSLVNDGPVTFWLQTRA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLPA_METHJ
Sequence: MIWQDGKLLSPGAVLPGDRVYHGMRIWDPGHSKVAALCHIHGEPPVRNARILYLGAAAGSTVSFLSDYAEVVYAVEFSPRPVRSLIRLARARKNIIPLFEDARYPERYLPFVEPVDLLIQDIAQRDQAEIALRNLIFLKQGGHLILFLKLLSMGTDKKREDRIVEVVNLLEHGGITDPAVLDLDRYHTGHTAVWGIYSLSKNFEK
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: ARGB_PROM0
Sequence: MNDSQRVSILSEALPYIQSFSGRKIVIKYGGSVMEDDDLKNAFFRDIALLSTVGVCPIVIHGGGPEINNWLKKLEISPKFENGLRITDQKTMEIVEMVLMGRVNKQIVKGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTKINPEILDPLISKGYIPIISSIGSTVEGISHNINADFVAGEIAAAISAEKLILLTDTQGILKEKDNKNSLVEKTNLKEARDLIDKKIVTEGMIPKTECCIRALAQGVKAAHIIDGRVQHSLLLEIFTNTGIGTMIVA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_BURMS
Sequence: MPTINQLVRKGRASETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRRQARSKYGAKRAKAAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MNMA_BURL3
Sequence: MSKRRVVVGMSGGVDSSVTAWLLKEQGYDVVGLFMKNWEDDDDGEYCSTRQDWIDVVSVADLIGIDVEAVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLDAEMIATGHYARVRERDGRFELLKAYDHTKDQSYFLHRLNQAQLSKTMFPLGEIPKTKVREIAAQIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTPDGKIVGEHIGLAFYTFGQRKGIGLGGSKSGNGDPWFVAAKDIASNTLYVVQGHDHPWLLARELVAGNVSWVAGEPPAEGFACGAKTRYRQADAACAFGAATPGPAGEARFSLAFDDAQWAVTPGQSAVLYDGEICLGGGIIESAVIGQPGQTAPARALAEAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_VIBPA
Sequence: MDLTNMGKAAKGAAFELATASTAQKNQALAIIADELEANSAAILAANAKDIELGREAGLTDALLDRLLLNEERLTGIANDVRNVISLNDPVGSEIDSKVLENGMSLSRRRVPLGVVGVIYEARPNVTIDIAALCLKTGNASILRGGKETFFSNMELVKVIQSALAKANLPAASVQYIEKPDRELVSQLLKLDDYVDMIIPRGGAGLHKMCKENSTIPVIIGGFGISHIFVDESADLEKSLNVVENSKVQRPSACNSLDTLLVHEKVAAKFLPMIVERMSDKVTFVAEPKAKALMAQATQIRDAVEGDFDTEWLSYTLGVKVVADVKEAIDHMRVHNASHSDAIMTNSLINSELFINSVGSAAVYVNAATRFTDGAQFGLGAEVAVSTQKLHARGPMGLEELTSYKWVGKANYLARS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_XYLFM
Sequence: MGCYSMGFVGRKAGMSRVFLEDGRSIPVTLIEATANRVVQIKTSDVDGYDAIQVTVGSRRSVLVNKPESGHFAKAKVEAGRGLWEFRVEKTQLGSYSVGSEVGLSIFAVGQKVDIQGITKGKGFQGTIKRHNFRMGDATHGNSLSHRAPGSLGQRQTPGRVFPGKKMSGHMGAVRQSVQNLEVIKIDVERFLIAVRGAIPGASGGDVLIRSASKI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PURQ_BACCQ
Sequence: MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKKLEENNQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_NOCSJ
Sequence: MSGHGAPAPAPVDCSDLRVAVVAASWHTQVMDGLIAGAQRALADYHVAEHRLVRVPGAFELAVVADALARQHYDVVVALGVVIRGGTPHFDYVCQAVTEGLVRVALDRSLPVGFGVLTCDGDQQALDRAGLEGSKEDKGYEATSAALLTARTLKELGTTAP
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RHAA_SALTY
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVAGFENPEGSLTGGIQSTGNYPGKARNATELRADLEQALRLIPGPKRLNLHAIYLESDTPVARDQIKPEHFKNWVEWAKANRLGLDFNPTCFSHPLSADGFTLSHPDAKIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLEALDEVISEKFDPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPRLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHNLFDRVHIGLDFFDASINRVAAWVIGTRNMKKALLRALLEPTDQLRQLEASGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSQWLDSVRVYEKEILSKRS
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDN1B_CANLF
Sequence: MSNVRVSNGSPTSERRDAKQAEYPKPSACRNLFGPVNHEELTRDLEKHCIDMEEASQNKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGTRQAGPLLGSQANSEDTHLVDQKTDAPDSQTGLAEQCTGIRKRPATDDSSPQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
What is the function of this protein?
Important regulator of cell cycle progression.  Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA.  Involved in G1 arrest.  Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes.  Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation.  Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1.
What is the protein family that this protein belongs to?
Belongs to the CDI family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endosome. Note=Nuclear and cytoplasmic in quiescent cells. AKT- or RSK-mediated phosphorylation on Thr-198, binds 14-3-3, translocates to the cytoplasm and promotes cell cycle progression. Mitogen-activated UHMK1 phosphorylation on Ser-10 also results in translocation to the cytoplasm and cell cycle progression. Phosphorylation on Ser-10 facilitates nuclear export. Translocates to the nucleus on phosphorylation of Tyr-88 and Tyr-89 (By similarity). Colocalizes at the endosome with SNX6; this leads to lysosomal degradation (By similarity).
Protein: SCB1_LEIHE
Sequence: MKIIIFLIVSSLMLIGVKTDNGYLLNKATGCKVWCVINNASCNSECKLRRGNYGYCYFWKLACYCEGAPKSELWAYATNKCNGKL
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  Competes, with apparent high affinity, with anti-insect and anti-mammalian beta-toxins for binding to cockroach and rat brain synaptosomes, respectively.  Also competes with an anti-mammalian alpha-toxin on binding to rat brain sodium channels.  Has a weak effect on cardiac sodium channels and a marked effect on rat brain and skeletal muscle sodium channels.
What are the official names of this protein?
Beta-mammal/insect toxin Lqhb1, Lqh-beta-1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARNA_SERP5
Sequence: MKAIVFAYHDIGCAGLKALTDAGYDIQAVFTHTDDPGENNFFSSVARVGAELELPVYAPEDVNHPLWIERIREMQPDIIFSFYYRNMLSEELLSLAPKGGFNLHGSLLPHYRGRAPVNWALVNGETETGATLHKMVKRPDAGDIVGQHKVAIAANDTALTLHKKVLEAAQALLKEQLPKLKNGTASFTRQNEAEASYFGRRTAADGEILWHKSAQEINNLVRAVTEPYPGAFSYLGQRKLIVWRARVLDTRHDKQPGTVLSTSPLIIACGEGALEIVAGQNDVGLYVQGSRLAQEMGIVTDVRLAAKPNAVMKRRTRVLILGVNGFIGNHLTERLLRDDRYDIYGLDIGSDAISRFLGNPRFHFVEGDISIHSEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRDCVKYNKRIIFPSTSEVYGMCDDKEFDEDHSRLIVGPINKQRWIYSVSKQLLDRVIWAYGAKEGLKFTLFRPFNWMGPRLDNLDAARIGSSRAITQLILNLVEGSPIKLMDGGAQKRCFTDINDGIEALFRIIENRDGLCDGQIVNIGNPTNEASIRELAEMLLESFNNHPLRDRFPPFAGFKDVESSSYYGKGYQDVEHRTPSIKNARRLLDWQPTIAMQQTVADTLDYFLRTTVQEGDGA
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: MURQ_BACTN
Sequence: MEFIKITEQPSLYDDLDKKSVKEILEDINTEDHKVADAVQKAIPQIEKLVTLIIPRVKKGGRIFYMGAGTSGRLGVLDASEIPPTFGMPPTVVIGLIAGGDTALRNPVENAEDDMSRGWEELLQHHINSEDTVIGIAASGTTPYVIGAMRTAREHGILTGCITSNPNSPMATEADVPIEVIVGPEYVTGSSRMKSGTAQKMILNMISTTIMIELGRVQGNKMVNMQLSNQKLIDRGTRMIIEELHLDYEKAEALLLLHGSVKSAIEAYRRHNSTQQE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: QUEA_PSEE4
Sequence: MRVADFSFELPDSLIARHPLAERHGSRLLVLDGPSGELAHKQFTDLLEYLRPGDLMVFNNTRVIPARLFGQKASGGKLEVLVERVLDSHRVLAHVRASKAPKEGAQILIDGGGEAEMVARHDTLFELRFSEEVLPLLERVGHMPLPPYIDRPDEGADRERYQTVYAERAGAVAAPTAGLHFDEALLEKIAAKGVERAFVTLHVGAGTFQPVRVDKIEDHTMHKEWLEVSQDVVDAVAACRARGGRVIAVGTTSVRSLESAARDGVLKAFSGDTDIFIFPGRPFHVVDCLVTNFHLPESTLLMLVSAFAGYPETMAAYAAAVEQGYRFFSYGDAMFITRNPAPRGPEDQA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCAO_ECOLI
Sequence: MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTRQSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAHQSLLKAYEKLQRAKAAFWAK
What is the function of this protein?
Involved in beta-methylthiolation of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase accessory factor YcaO.
Protein: BIOB_BRUA2
Sequence: MPDRGGENGASCSVGRWSAEEARAIYNLPFNDLLFRAHGLHRENFDPNRIQLSKLLNIKTGGCPEDCGYCSQSASAENGLKASKLMEIETVLEEARKAKAAGATRYCMGAAWRSPKDRDMPALTHMIESVKAMGLETCMTLGMLDSDKAEKLADAGLDYYNHNIDTSERFYPAVITTRSFEDRLDTLANVRNAGIKVCSGGILGLGEEAEDRIDMLVTLANLPEPPESVPINMLIPMPGTRLAKAAPVDPLEFVRVVALARILMPKSHVRLTAGRTAMSDEMQALCFFAGANSLFMGDTLLTAANPGDDRDSSLLRRLGIQAETEQPA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: FLIE_BURL3
Sequence: MTANVSGIGSVLQQMQSMAAQASGGVASPTAALAGSGAATASTFASAMKASLDKISGDQQHALGEAQAFEVGAPNVSLNDVMVDMQKANIGFQFGLQVRNKLVSAYNDIMQMSV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: EFP_BRUAB
Sequence: MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAESVERVRLEQKDFSFLYEQGEALIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEKPIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIRIPVPPFIASGERVIVDTNELTYISRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAI_LIRTU
Sequence: MTDFNLPSIFVPLVGLVFPAIAMASLSLHVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GLGA_BACCN
Sequence: MNILFAVSECVPFIKSGGLADVAGALPKELKKLGVNVRIMLPNYSLIPANLRESFKLHKVIHVPLGWRNQYCGILKGEQDGITYYLIDNEYYFKRDSLYGHYDDGERFSFFSKAILESIPYLDFEVDLIHSHDWHTAMVNFLLHEKYKDNPLYEKIKTVYTIHNLQFQGVFPREVIHDLLELGDEYFNSEQLEFYGNINFMKGGIIAADHITTVSSTYKEEIQYEFFGEKLDGLLRKYNDKLSGIVNGIDTSVYNPRLDSYITATYDVDTLYAKRENKWALQHYFGLPEKENTPIISMVTRLTKQKGLDLVRAVFQEIMQEDVQCIILGSGDSEYEQFFEWMAYEYSEKVKVYIGFNEELAHQVYAGSDLFLMPSLFEPCGLGQLIALTYGVIPIVRETGGLNDTVKSYHVETKSGNGFTFTNFNAHDMLYTVRRALRYYEDPAVWNQLVKQAMTEDHSWKTSALAYKDLYNRLLKLS
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: FAR2_STRNA
Sequence: ADYLQLAR
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-2, FMRFa-2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: COFG_SYNP6
Sequence: MKHFSDQTWRSPQQSAVITYSPAYTLVPTYECFNRCTYCNFRRDPGMDEWLSLSTAQQRLLTVRDRGVCEVLILSGEVHPQSPRRAAWRQRLIELAELALDMGFLPHTNAGPLNRAEMIALQNVNVSLGLMLEQLTPQLQRTVHRAAPSKDPQLRLQQLEQAGELGIPFTTGLLLGIGETSRDRLETLEAIAACHDRWGHIQEVILQPHSPGRQQAIQHPPLAPDELIDCVAIARQVLPTSIAIQVPPNLLTQPQQLADCLGAGARDLGGIVPYDEVNPDYQHHDLDELREALAQQGWQLQPRLPVYPHLVDRLPQRLQTHVAAWLNRFNSQSRSS
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: DFB4A_PANTR
Sequence: MRVLYLLFSFLFIFLMPLPGVFGGISDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
What is the function of this protein?
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria, with highest activity against Gram-negative bacteria (By similarity).  Antimicrobial activity against P. aruginosa seems to be salt-sensitive and is reduced with high salt concentrations greater than 25 mM (By similarity).  Also exhibits antimicrobial activity against the yeast C. albicans (By similarity).  Permeabilizes C. albicans cell membranes via targeting plasma membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), thereby leading to cell fragmentation and cell death (By similarity).  Acts as a ligand for C-C chemokine receptor CCR6 (By similarity).  Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells, such as immature dendritic cells and memory T cells (By similarity).
What are the official names of this protein?
Defensin beta 4A, Beta-defensin 2, BD-2, Defensin, beta 2.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family. LAP/TAP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RRP36_KLULA
Sequence: MSFYFKNIKPDLHSGNEDEEDDIASIIRINDTSDAEGSQSEDELKTLSFGSLKKADEMMDNEEQTSRKSKSKANGEKKHLNKPKSRELTEKQRKLDDGQRRQSGLQEEEAQQKSQSIKMFAEESFGEESDSDSDGGFFDEESNDEANQNGKKKKGKRKHAPTESSSKKKVRSMRKIPGLEDNKSKSIYQDVRFDKAMGKSEDLAKIRQRYKFLDEYREKEINELDSMLHDRKFLSKISDREKSEMEQQVRRMKSRLETVQVMEMEQKIVKDYEAEINKNNKNKYHLKDSEKRKVIQKWKFEHMKGKQREKVMDRKRKKRLGKEFKQFEFHKR
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PARVG_MOUSE
Sequence: MELEFLYDLLQLPKEVAQPTEEELPRGGKKKYLSPNSKRNPKFEELQKVLMEWINTTLLPEHIVVRSLEEDMFDGLILHHLFQKLASLKLEVEEISLTSASQRHKLGVILEAVNQNLQVEEKQAKWSVETIFNKDLLATLHLLVALAKRFQPDLPLPDNVQVEVIHIESTKTGLKSDKQVEQLTECKSHKDQPLQDAFDELFKLAPEKVHAVQEAIVSFVNQKLERLGLSVQSLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPSSPTEMLHNVTLALDLLKDEGLFSYPVNPEDIVNKDAKSTLRILYSLFQKHSLRAEGGGAHHATPN
What is the function of this protein?
Probably plays a role in the regulation of cell adhesion and cytoskeleton organization.
What are the official names of this protein?
Gamma-parvin.
What is the protein family that this protein belongs to?
Belongs to the parvin family.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Constituent of focal adhesions.
Protein: KDPC_SHISS
Sequence: MSGLRPALSTFLFLLLITGGVYPLLTTALGQWWFPWQANGSLIREGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPELDKLIAARVAALRAANPDASASIPVELVTASASGLDNNITPQAAAWQIPRIAKARNLSVEQLTQLIAKYSQQPLVKYIGQPVVNIVELNLALDKLDE
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRPA_HELPY
Sequence: MRYQNMFETLKKHEKMAFIPFVTLGDPNYELSFEIIKTLIISGVSALELGLAFSDPVADGITIQASHLRALKHASMAKNFQLLKKIRDYNHNIPIGLLAYANLIFSYGVDGFYAQAKECGIDSVLIADMPLIEKELVIKSAQKHQIKQIFIASPNASSKDLEQVATHSQGYIYALARSGVTGASRILENDSSAIIKTLKAFSPTPALLGFGISKKEHITNAKGMGADGVICGSALVKIIEENLNNENAMLEKIKGFIGGMIF
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.