PharMolix/UniProtQA huggingface dataset:
Protein: SLMA_SALA4
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKNTSTRLRLIVLLILGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDENLLASQLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MURG_LISIN
Sequence: MKVAISGGGTGGHVYPALAFIRELKKVHPEAEFLYIGTEKGLEAGIVKREGIPFESIEITGFKRSLSLENIKTVMRFLSGAKKSKQILREFKPDVVIGTGGYVCGPVVYAAAKLKIPTLIHEQNSIAGLTNKFLSRYTDKVAICFEEVSDSFASEKIVFTGNPRASEVVGVDGEGALEAYGLVSGKPTVLVFGGSRGARGINEAVEAILPEWNKRDFQLLYVTGDVHFEKIKDSLGEMNLGNHISVQPFIYDMPKILNAVTLVVSRAGATTLAELTALGVPSILIPSPYVTANHQEYNARALEKNNAAVVITESELKETDLMATVDAILTDEAKLNSMKLSAKQMGRPDAALKLVETVLSIMK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LPXA_VIBVY
Sequence: MIDATAQIHPTAVVEEGAVIGANVKIGPFCYVDSKVEIGEGTELLSHVVVKGPTKIGKENRIFQFASIGEQCQDLKYAGEDTQLVIGDRNTIRESVTMHRGTVQDKGITIVGSDNLFMINAHVAHDCVIGDRCIFANNATLAGHVKVGNQAIVGGMSAIHQFCHIGDHCMLGGGSIVVQDVPPYVMAQGNHCAPFGINVEGLKRRGFEKKEILAIRRAYKTLYRSGLTLEAAKEEIAKETEAFPAVKLFLEFLEKSQRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_YARLI
Sequence: MAIKVGINGFGRIGRIVLRNALKNPEVEVVAVNDPFIDTEYAAYMFKYDSTHGRFKGKVEAKDGGLIIDGKHIQVFGERDPSNIPWGKAGADYVVESTGVFTGKEAASAHLKGGAKKVIISAPSGDAPMFVVGVNLDAYKPDMTVISNASCTTNCLAPLAKVVNDKYGIIEGLMTTVHSITATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVIPELNGKLTGMSLRVPTVDVSVVDLTVRIKNGASYEDIKATMKAASESPELKGILGYTDEDVVSTDFIGDTHSSIFDAKAGIGLNDNFVKLISWYDNEYGYSARVVDLIVAVAKKDASA
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF2D_PONAB
Sequence: MFAKAFRVKSNTAIKGSDRRKLRADVTTAFPTLGTDQVSELVPGKEELNIVKLYAHKGDAVTVYVSGGNPILFELEKNLYPTVYTLWSYPDLLPTFTTWPLVLEKLVGGADLMLPGLVMPPAGLPQVQKGDLCAISLVGNRAPVAIGVAAMSTAEMLTSGLKGRGFSVLHTYQDHLWRSGNKSSPPSIAPLALDSADLSEEKGSVQMDSTLQGDMRHMTLEGEEENGEVHQAREDKSLSEAPEDTSTRGLNQDSTDSKTLQEQMDELLQQCFLHALKCRVKKADLPLLASTFLGSHMFSCCPEGRQLDIKKSSYKKLSKFLQQMQQEQIIQVKELSKGVESIVAVDWKHPRITSFVIPEPSPTSQTIQEGSREQPYHPPDIKPLYCVPASMTLLFQESGHKKGSFLEGSEVRTIVINYAKKNDLVDADNKNLVRLDPILCDCILEKNEQHTVMKLPWDSLLTRCLEKLQPAYQVTLPGQEPIVKKGRICPIDITLAQRASNKKVTVVRNLEAYGLDPYSVAAILQQRCQASTTVNPAPGAKDSLQVQIQGNQVHHLGWLLLEEYQLPRKHIQGLEKALKPGKKK
What is the function of this protein?
Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner.  The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs.  Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety.  Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit.  In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 2D, eIF2d, Ligatin.
What is the protein family that this protein belongs to?
Belongs to the eIF2D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN622_HUMAN
Sequence: MATYTCITCRVAFRDADMQRAHYKTDWHRYNLRRKVASMAPVTAEGFQERVRAQRAVAEEESKGSATYCTVCSKKFASFNAYENHLKSRRHVELEKKAVQAVNRKVEMMNEKNLEKGLGVDSVDKDAMNAAIQQAIKAQPSMSPKKAPPAPAKEARNVVAVGTGGRGTHDRDPSEKPPRLQWFEQQAKKLAKQQEEDSEEEEEDLDGDDWEDIDSDEELECEDTEAMDDVVEQDAEEEEAEEGPPLGAIPITDCLFCSHHSSSLMKNVAHMTKDHSFFIPDIEYLSDIKGLIKYLGEKVGVGKICLWCNEKGKSFYSTEAVQAHMNDKSHCKLFTDGDAALEFADFYDFRSSYPDHKEGEDPNKAEELPSEKNLEYDDETMELILPSGARVGHRSLMRYYKQRFGLSRAVAVAKNRKAVGRVLQQYRALGWTGSTGAALMRERDMQYVQRMKSKWMLKTGMKNNATKQMHFRVQVRF
What is the function of this protein?
Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit.
What are the official names of this protein?
Cytoplasmic 60S subunit biogenesis factor ZNF622, Zinc finger protein 622, Zinc finger-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the REI1 family.
Protein: SDA1_BOVIN
Sequence: MSSRNNNKLPSNLPQLQNLIKRDPPAYVEEFLQQYNHYKSNVEIFKLQPNKPSKELAELVMFMAQISHCYPEHLSNFPQELKDLLSYNHTVLDPDLRMTFCKALILLRNKNLINPSSLLELFFELLRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNIVLQNFMYTMLRDSNATAAKISLDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEEEKQDSDSESEDEGPTARDLLVQYATGKKSSKNKKKLEKAMKVLTKHKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQLESSKERFEVKMMLMNLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQYKTHKDKNVMMSARTLIQLFRTLNPQMLQKKFRGKPTEASIEARVQEYGELDAKDYIPGAEILEVENEEENAEGDEDGWESASLSDEADSDGEWVDVHHSSDEEQKEISEKLNSMPLEERKAKAAAVSTSRVLSQEDFQKIRMAQMRKELDAAPGKAQKRKYIEIDSDEERRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKMNPFSSSTNKEKKKQKNFMMMRYSHNVRSKNKRSFREKQLALRDALLKKRKRMK
What is the function of this protein?
Required for 60S pre-ribosomal subunits export to the cytoplasm.
What are the official names of this protein?
Protein SDA1 homolog, SDA1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SDA1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: AROA_MYCVP
Sequence: MSTWPAPSTATPVHATVTVPGSKSQTNRALVLAALAVPQGSSTISGALRSRDTDLMISALQGLGVVVEAPDTDGSDGTELTVSGALAPKAGARIDCGLAGTVLRFVPPVAALTTETVTFDGDEQARARPIAPLLDGLRALGVAIDGDGLPFSVRGQGSVRGGTVEIDASGSSQFVSGLLLSGAAFTEGLTVVHTGGAVPSAPHIAMTVSMLRDAGVEVDDSAADRWRVAPGPIAARHWAVEPDLSNAVPFLAAAVISGGTVRVTGWPTVSTQPAATILSLLTSLGSEVRQGNSHLEVQGATSYDGIDVDLRDVGELAPSVAAMAALASPGSVSRLRGIAHLRGHETDRLAALSAELNRLGGQCEETDDGLVITARQMHGGVWRSYADHRMATAGAIVGLRVPGVEVEDIGTTAKTLPDFPQLWADMLAGQTDLQAGAPHAGRNQGR
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTK2_CANGA
Sequence: MTVATEKTPHKSSSMFKLFSNKLRGNNDSTPAAAPAPVPTKKLTKAHTSAHISRSASTNTPHPLRNGVTGIPSASPAPRQMTRRSTGVTPTMVKSSKQLSTLTAHNSNPFRNKNGTISSASHTHNGPTNSQHMVYNPYGINNRPTETQSSVRGSSYSRHGSGSHISSGSASSTNNNTDLSFYMHDGDNKIRMLPLPIADPNEFLPDDIKQVSIHLSDNFSFDKDNKTIGSGGSSEVRIVRSNYRSKDVYALKKLNMIYDETPEKFYKRCSKEFIIAKQLSNNIHITSTFYLVKVPTTIYTTRGWGFIMELGSKDLFQLMEKSGWKNVPLHEKFCLFKQVAQGVKFCHDNGIAHRDLKPENVLLSKDGVCKLTDFGISDWYHKENEDGTIEVKQNAGMIGSPPYAPPEVMYWDAKKKYPTSMQKPYDPLKLDCYSLGIIFITLINNIIPFFESCNMDPKFREYENSYNNFIRYQNKNFRQKGTYKPGPGSEYMLARRFKNADASRVAWRLADPDPETRYTMEDLFNDPWFQSVETCVDVNDVNLVRHPQIKKTSSEGINLVNAADAHPIPSPMVGTDTNGGLHSDSENPAGTHTTEESVETPKPASIRELHKPRSMVDIAESPMKKAATTPLFTLDEEAKEERDHEQETNTTAEADNEKAQTVPTSAVDTNEFASKENATTTDNDNVNTKATTADPTTQQGAEITETGSIAGSISASISASITASMSGSVSGAATAPIPRRDPSNRSIHSNATSTGTAGRKKKVVHHHMEVPGSAFQI
What are the official names of this protein?
Serine/threonine-protein kinase PTK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: YD85A_YEAST
Sequence: MRFFLFPYERFQLHQPLFLFFSICFLTLRMKERLLRYNLRYLYALRNVFGTFYSNQRSNQNVATLSKEPFLVFSF
What are the official names of this protein?
Putative uncharacterized protein YDL185C-A.
Protein: XYN5_MAGO7
Sequence: MTRLATLITLAGLLAVSPGAYAQRNRNDTGGSTGAEGLNSLAVKAGLLYFGTASDTRNFADEPYMSVVNNTNEFGMIVPENSMKWEATEKEPGRFSFANADRVRALTKANGQMLRCHALTWHSQLPNFVKTTAWTRDTLTAAIESHISNEVGHFAGDCYAWDVVNEAVNENGSFRDSPFHRTLGTDFLAISFRAAAAADPNAKLYYNDFNIETPGPKANAAMGIVRLLKEQGVRIDGVGFQGHLTVGSTPSRAQLASQLQRFADLGVEVTYTELDIRHKSLPVSSRAAQDQARDYVSVIGSCLDVTACVGVMVWQPTDKYSWIPETFPGTGDACLFDANMNPKPAYTSVSSLLAAAAATAPASVVPPASVTTSKTPIQAGAGRETVSIAGLTLALSSLAFGMFML
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase 5, Xylanase 5, 1,4-beta-D-xylan xylanohydrolase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted.
Protein: CT2BB_BACTJ
Sequence: MYTKNLNSLEINEDYQYSRPIIKKPFRHITLTVPSSDIASFNEIFYLEPQYVAQALRLTNTFQAAIDPLTLNFDFEKALQIANGLPNAGITGTLNQSVIQQTIEISVMISQIKEIIRNVLGLVINSTNFWNSVLAAITNTFTNLEPQVDENWIVWRNLSATHTSYYYKILFSIQNEDTGAFMAVLPIAFEITVDVQKQQLLFITIRDSARYEVKMKALTVVQLLDSYNAPIIDVFNVHNYGLYQSNHPNHHILQNLNLNKIKG
What is the function of this protein?
Kills the larvae of dipteran insects by making pores in the epithelial cell membrane of the insect midgut.
What are the official names of this protein?
Type-2Bb cytolytic delta-endotoxin, 30 kDa cytolytic toxin.
What is the protein family that this protein belongs to?
Belongs to the cyt1/cyt2 endotoxin family.
Protein: DEFN_HELVI
Sequence: DKLIGSCVWGAVNYTSDCNGECKRRGYKGGHCGSFANVNCWCET
What is the function of this protein?
This peptide has potent anti-fungal activity.  Has no activity against Gram-negative and Gram-positive bacteria.
What are the official names of this protein?
Defensin heliomicin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SPRT_SALHS
Sequence: MKTPRLPIAIQQAVMRRLRENLAQANLKLDRHYPEPKLVYTQRGTSAGTAWLESYEIRLNPVLLLENIDTFIAEVVPHELAHLLVWKHFGRKAPHGKEWKWMMESVLGVPARRTHQFALQSVRRNTFPYHCQCQQHQLTVRRHNRVVRGEAVYRCVHCGEPLVAG
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWLO_BACLD
Sequence: MKKKVYTFGLASILGTASLFTPFMNNTASAETSQQKQEIQQKRSEVNSGIESKRKEIAKLQDEQKKLEGKIQELDKKALETSNKIEDKEKENKKTKKEVEALKKEIKETEKRIEERSKVIKNRVRSLQENGGSQNYLNVLLGAQSFGDFITRATAVSTIVDADKDLLDEQEKDKNKLEKAMSDLNTKLDEIQKTLADLKTLKSDLDKQLKEQANLSKQLQTKQAAAESELSDLKKEAGSLTKEEAALEQKLKEERAAAAAAAKAKEESATAEKSDSGSSSSSNSGSVSKSDGSSNSGSSSSKKSSSPSRNYSSGSVVSSNGNAIEAAISTGSSIVGRSPYKWGGGRSQADIDNRRFDCSSFVRWAYASAGVELGFGATTSTLVGKGRAVSASEMKRGDLVFFDTYKTNGHVGIYLGNGTFLNDNSSRGVSVDSMSNPYWKKAFNGVVRRVVE
What is the function of this protein?
Shows a cell wall hydrolytic DL-endopeptidase activity.
What are the official names of this protein?
Peptidoglycan DL-endopeptidase CwlO, D-gamma-glutamyl-meso-diaminopimelyl DL-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPA_RHYMA
Sequence: SGLDSLSGATFGGNR
What is the function of this protein?
Myoactive peptide.  Increases the amplitude and frequency of spontaneous contractions and tonus of hindgut muscle.
What are the official names of this protein?
Tachykinin-related peptide 10, LemTRP 10.
What are the subcellular locations of this protein?
Secreted.
Protein: PRDX4_RAT
Sequence: METWSKLLDGTTPSRRWRKLVLLLPPLLLFLLQTEALQGLESDDRFRTRENECHFYAGGQVYPGEVSRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.  Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
What are the official names of this protein?
Peroxiredoxin-4, Antioxidant enzyme AOE372, Peroxiredoxin IV, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372, Thioredoxin-dependent peroxiredoxin 4.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Secreted.
Protein: TRMD_CHLT3
Sequence: MRVDIISVLPDFFDSPLANGLLRIAREKQRLQLHVHSLREYGLGKYKQVDDTPFGGGAGMVLRVEPVFACIEKLKADRDYDEVIFFTPDGKQFNQSEANRHALDRNLILLCGHYKAIDERIRETLITKEISLGDFVLSGGELPALIFLDSVARLLPGVLHDEESMLTDSFQDGKLDCAHYTRPSEFRGMKVPDVLLSGNHKKIEEWRLENAIERTRQRRPDLLKDINL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_ACIAD
Sequence: MKDVIKDLSELRMSYEKGELHEAQVDTHPHEQFLQWFNHALQSNLHEPYAMSLATCNRQGRPHVRTVLLRGATAQGYDFYTNYDSQKGIDLAENPYAELLFYWPSLERQVRIGGIVNKISEHESTDYYHKRPRDSQIAAHISTPQSGIIANREELQQRFNRLYEQVGQQTVLSKPEFWGGYRLQADYYEFWQGRPNRLHDRLSYQNTDGTWVVQRLMP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: TCYL_ECOLI
Sequence: MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDTSLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK
What is the function of this protein?
Part of the ABC transporter complex TcyJLN involved in L-cystine import (PubMed:25139244, PubMed:20351115, PubMed:25837721, PubMed:26350134).  This high affinity cystine transporter is involved in resistance to oxidative stress by forming a L-cysteine/L-cystine shuttle system with the EamA transporter, which exports L-cysteine as reducing equivalents to the periplasm to prevent the cells from oxidative stress.  Exported L-cysteine can reduce the periplasmic hydrogen peroxide to water, and then generated L-cystine is imported back into the cytoplasm via the TcyJLN complex (PubMed:20351115, PubMed:25837721).  Functions at low cystine concentrations (PubMed:26350134).  The system can also transport L-cysteine, diaminopimelic acid (DAP), djenkolate, lanthionine, D-cystine, homocystine, and it mediates accumulation of the toxic compounds L-selenaproline (SCA) and L-selenocystine (SeCys) (PubMed:25139244, PubMed:26350134).  Responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
L-cystine transport system permease protein TcyL.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PFPA_SOLTU
Sequence: MDADYGIPRELSDLQKLRSHYHPELPPCLQGTTVRVELRDATTAADPSGEHTIKRFFPHTYGQPLAHFLRATAKVPDAQIITEHPAIRVGVLFCGRQSPGGHNVIWGLHDALKVHNPKNILLGFLGGSEGLFAQKTLEITDDVLATYKNQGGYDMLGRTKDQIRTTEQVNAAMAACKALKLDGLVIIGGVTSNTDAAHLAEKFAETKCLTKVVGVPVTLNGDLKNQFVEANVGFDTICKVNSQLISNVCTDALSAEKYYYFIRLMGRKASHVALECTLQSHPNMVILGEEVAASKLTIFDITQQICDAVQARAEHDKNHGVILLPEGLIESIPEVYALLQEIHGLLRQGVSADKISSQLSPWASALFEFLPHFIRKQLLLHPESDDSAQLSQIETEKLIAHLVETEMNKRLKEGTYKGKKFNAICHFFGYQARGSLPSKFDCDYAYVLGHVCYHILAAGLNGYMATITNLKNPANKWHCGASPISAMMTVKRYGRGPGKASIGVPALHPATVDLRGKSYELLSQNATKFLLDDVYRNPGPLQFDGPGADAKAVSLCVEDQDYIGRIKKLQEYLDKVRTIVKPGCSQDVLKAALSAMASVTDILSVISSPSSVSTPF
What is the function of this protein?
Regulatory subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha, PFP, 6-phosphofructokinase, pyrophosphate dependent, PPi-PFK, Pyrophosphate-dependent 6-phosphofructose-1-kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_GEOSE
Sequence: MLKRLLSKCAEGETLTEAEAYEAMNAVMSGEATDSQIASLVSILRVRGETVDEIAGFVRAMRDRMTTIDAGDDVIDTCGTGGDGAATFNVSTAAAIVVSSLGVKVAKHGNRAVSSKSGSADVLERLGIDIPASPEAAKQALETKGLAFLFAPLYHAAMKYAAGPRKEIGFRTIFNLIGPLANPARCKRQVIGVYSTRYAEKLAETMRRLGSEHVVFVTGRDGLDECSIAAETDVVELKDGDIRRFVLTPESVGLRXGGLADVQVRSSEESAALLEAVMDGTAPASAIDITALNAGVALYAAGKAETIAAGVAMAKDAILVKTAYEQLQRLRRKEVVHGA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: BTUC_ECO45
Sequence: MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWFTPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGEISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HRCA_STRU0
Sequence: MITERQNEILNLIIDLFTQTHEPVGSKALQASIETSSATIRNEMAKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLSLDSVDESDIYQLVKAFDFEAFRLEDILAKASQVLADMTHYSVAILDVEPSHQKLTAFDIVQLSNHDALAVLNLDESKPQTVQFAIPKNFLTRDLVKIKEIVDERLLGRNLMDVHYKLRTEIPQILQKYFTVTDNVLDLFEYIFRELFQESIFVSGKVNALEYAGLDTYQFLNNEQHLAFTIRQGMSENEMATVQVADSNEPALANLSLLTYKFLIPYRGFGLLSLIGPIDMNYRRNVSLINVMGRILAIKLRDYYRYLNSNHYEVN
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: Y535_PYRFU
Sequence: MKTFLTEQQIKVLMLRAKGYKQSEIAKILGTSRANVSILEKRAMEKIEKARNTLLLWEQINSKVIVEIKAGEDIFSIPEKFFKKADKVGVKVPYSTAEIITFLVEHAPVEDRLAKRDFVLFLDSKNKLRIGDCLVIEEIKED
What is the function of this protein?
Putative transcriptional regulator.
What are the official names of this protein?
Putative transcriptional regulatory protein PF0535.
What is the protein family that this protein belongs to?
Belongs to the Tfx family.
Protein: ARGC_BUCA5
Sequence: MLNVVIVGASGYAGAELVNYMHRHRFANIKKIFVSKNSLNIDKLFSDVHQQFKNIVDLRFDTIRNCTLIKKNIDAVFLATDHRVSHSLVPFFLSSNCIVFDLSASYRMNNKKVYLDYYGFVHEYEELLKNSVYGLAEWEQEKIKKANLIALPGCYATCIQLALKPLIKENVLCDKNIPIINAISGVSGAGRKASLNNSFCEVSLQPYNIFTHRHTPEIIEKLGVPVIFIPHLGPFSRGIIATITCKLKPNVKSIDIHNIFNKFYKNKPLIRIYKKYLPSIKSVEKQPFCDIGFVIKDDYIVIVAAEDNLLKGAAAQAVQCFNVRFGFSETESII
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_BURM9
Sequence: MKLTPREKDKLLIFTAALLAERRRARGLKLNYPETVAFITAALMEAARDGRTVAEVMHYGTTLLTRDDVMEGVPEMIPDIQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3995_MYCSS
Sequence: MASTDDPAGQRPSRAEAIVAHAEQSISEDAIVAAARERAVDMGAGAVTPAVGALLSVLARLTEAKAVVEVGTGAGVSGLWLLSGMREDGVLTTIDVEPEHQRIAKQAFTEAGIGPGRTRLISGRAQDVLTRLADESYDLVFIDADPVDQPQFVVEGVRLLRSGGAIVVHRAALGGRAGDAGANDAEVSAVREAARLIAEDERLTPVLIPLGDGLLAAARD
What are the official names of this protein?
Putative O-methyltransferase Mmcs_3995.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: ARGR_MYCTO
Sequence: MSRAKAAPVAGPEVAANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELGAVKLRGADGGTGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNLAVLRTPPGAAHYLASAIDRAALPQVVGTIAGDDTILVVAREPTTGAQLAGMFENFGKESHVRARHPGLFRRSGHLGGDQLDRQGDRP
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.