PharMolix/UniProtQA huggingface dataset:
Protein: RS17_PELUB
Sequence: MPKKILTGVVTSDKPNKTITVSVERKYSHPVLKKVVKVRKKYNAHDENNKFKTGDTVSIIECKPFSKNKKFQVMDESK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS29_PLUXY
Sequence: MGHANIWYSHPRKYGQGSRSCRACSNRHGLIRKYGLNICRQCFREYANDIGFKKLD
What are the official names of this protein?
40S ribosomal protein S29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: IL18R_HUMAN
Sequence: MNCRELPLTLWVLISVSTAESCTSRPHITVVEGEPFYLKHCSCSLAHEIETTTKSWYKSSGSQEHVELNPRSSSRIALHDCVLEFWPVELNDTGSYFFQMKNYTQKWKLNVIRRNKHSCFTERQVTSKIVEVKKFFQITCENSYYQTLVNSTSLYKNCKKLLLENNKNPTIKKNAEFEDQGYYSCVHFLHHNGKLFNITKTFNITIVEDRSNIVPVLLGPKLNHVAVELGKNVRLNCSALLNEEDVIYWMFGEENGSDPNIHEEKEMRIMTPEGKWHASKVLRIENIGESNLNVLYNCTVASTGGTDTKSFILVRKADMADIPGHVFTRGMIIAVLILVAVVCLVTVCVIYRVDLVLFYRHLTRRDETLTDGKTYDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIEKSRRLIIVLSKSYMSNEVRYELESGLHEALVERKIKIILIEFTPVTDFTFLPQSLKLLKSHRVLKWKADKSLSYNSRFWKNLLYLMPAKTVKPGRDEPEVLPVLSES
What is the function of this protein?
Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B (PubMed:8626725, PubMed:14528293, PubMed:25261253, PubMed:25500532).  Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850).  Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity).
What are the official names of this protein?
Interleukin-18 receptor 1, IL-18R-1, IL-18R1, CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, IL-1Rrp, IL1R-rp, Interleukin-18 receptor alpha, IL-18R-alpha, IL-18Ralpha.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein.
Protein: RPOC_BACC1
Sequence: MIDVNNFEYMKIGLASPDKIRSWSYGEVKKPETINYRTLKPEKDGLFCERIFGPQKDWECHCGKYKRVRYKGVVCDRCGVEVTRAKVRRERMGHIELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEVIYFASYVVTESGDTPLDKKQLLSEKEYRAYRDRYGSTFQAAMGAEAIKKLLQDIDLDKEVDFLKEELKTAQGQRRTRAIKRLEVLEAFRNSGNEPSWMILDVLPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPSIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKMYQCGLPKEMALELFKPFVMKELVEKGLAHNIKSAKRKIERVQPEVWDVLESVIKEHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVCTAYNADFDGDQMAVHVPLSSEAQAEARLLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLEREGAIGEGMVFKDANEALLAYQNGYVHLHTRVAVAASAVNNATFTEEQKSMLLLTTVGKLIFNEILPESFPYINEPTNSNLEKETPAKYFVEKGANIKEIIASREEVAPFSKKILGNIIAEVFKRFKITETSRMLDRMKNLGFKYSTKAGITVGVSDILVLGEKDEILHEAQAKVDNVIKQFRRGLITEEERYDRVISIWSNAKDVIQGKLMKSLNKRNPIFMMSDSGARGNASNFTQLAGMRGLMANPSGRIIELPIKSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIVREDDCGTDRGLLIGAIKEGNEVIESLYDRLVGRFARKTVKHPETGEVLVAENQLITEDIAHIVENSGVETVNIRSAFTCNTRHGVCKKCYGRNLATGTDVEVGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRIQEIFEARNPKGQAVISEIDGVIAAINDVKDRQEVVVQGEVETRTYAIPYGARLKVIPGQQISHGKELTEGSIDPKELLKVTDITAVQEYLLREVQKVYRMQGVEIGDKHVEVMVRQMLRKVRVSDAGETDVLPGTLLDIHQFTDANAKVLLQGKQPATARPVLLGITKASLETDSFLSAASFQETTRVLTDAAIKGKRDELLGLKENVIIGKLVPAGTGMNRYRKVDLVKTTQDDMNVENDEVYVEQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CR18_RANCH
Sequence: GLFKVLGSVAKHLLPHVVPVIAEKL
What is the function of this protein?
Antimicrobial peptide (PubMed:9516047).  Adopts an alpha helical conformation which can disrupt bacterial membranes (PubMed:9516047).  Strongly inhibits the formation of NO by neuronal nitric oxide synthase (nNOS) at micromolar concentrations (PubMed:11784303).  Acts by a non-competitive mechanism, probably by binding to calcium/calmodulin and as a consequence blocking calmodulin attachment to nNOS (By similarity).
What are the official names of this protein?
Caerin-1.8.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TALA_ECOL6
Sequence: MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase A.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_MESH7
Sequence: MDSTILIKLSGESLANKQKSLAIDYELVRQIGSQLKEIQNLGHKILIVIGGGNFWRGTSAAKNGINRNTADYIGMLGTVMNGLALDSVFRDLGIKTRVLSSMSLDPRICEYFVREKAMKYLEDNNVLIFVGGTGRPFFTTDSAATLFASEMGANIILVGKNNVNGIFDSDPKINPNALRYDKITYNQVIEKNLKVMDSTAFSMARDNKIKLLIFDIKEKNSISKLIKRQIKHTEVY
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_MARMS
Sequence: MLDIKALRADPEAIAAQLKKKGYELDVATFSSLEERRKAIQVETEQLQQARNSVSKEIGQAMKSGDKDKAAELKAQTATLGDDLEAAKTQLTQVQEELESLLEGIPNLPHASVPEGKTEDDNVEIRRWGTPKQFDFEPKDHVDLGEAMEMLDFEAAVKITGSRFAVMHSDLARLHRALTQFMINTHADLHGYTEVYVPYLVNAHSLKGTGQLPKFEADLFKVPVDKDSGNNDLYLIPTAEVPVTNLVRDEILNDADLHKKFVAHTPCFRSEAGSYGRDTRGMIRQHQFEKVELVHVCRPDISEQVLEELVGHAEVILQKLELPYRTVILCGGDLGFSAHKTYDIEVWLPGQGKYREISSCSNMWDFQARRMQARWRNPETGRPELAHTLNGSGLAVGRTLVAVLENYQNADGSVRVPDVLVPYMGGKTVLKKA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_FRATF
Sequence: MSEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDTDYAIRIDFDKDAKTITVSDNGIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIGQFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNGFTVEIITKEKRGTEVILHIKKEHLDLLEYHVLKGLVNKYSDCINTPIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSKGEVTNEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLSLYVRRVFIMENKELLPPYLRFVKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSELKKLASKDKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGLLRFATTQSGDSKQTVSLADYISRMKESQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDDKHMKSIIKGDIDLDKFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSCVVVNDYGMSLHMQKMMEEAGQSFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSELLLLQAMFVEGAKIEDPMAFVKLVNKYIR
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_THEAC
Sequence: MTDDYEKLLEKAKNVLSSSTKNIDRLKIPDPEIIREGKATIIRNFQDIVDIINRDPEHIIKFLTREFGTNIVQNGRRLIINRKLTLEELLDKMNEYINTYVRCYECGSLDTEIQKSGRISLLVCKACGAQHPIHSVREAKDDETIEEGKEYVVEITEVGSSGEGRTNYKGYTIFVPGAKRGETVKVRIKKVKNDVAIGEIIERSKQEKK
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: PDRP_BRUMB
Sequence: MTRPLSYFHLHLISDATGETLLAAGRAAAAQYANARAIEHIYPLIRTEKQLRKVLEGIDAEPGIVLYTVVDQKLAAIIDESCADMGVPSVSVLEPVLNTFQSYLGAPAHRRASAQHVLNADYFRRIDALNFMMEHDDGQLPLDIEEADVIIVGISRTSKTPTSIYLANRGIKAANVPLVLGIPVPEILFAAKRPLIVGLVATAERISQIRQNRPIGNIPSLDTGLYTDRVSISEELAYARNLCNRHGWPIIDVSRRSIEETAAAILALLRNGKKEGSSS
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: FENR2_BACAH
Sequence: MKVAENQKVYDITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKVRAQELVDNLKEQMKKFDPTVCLEEAVDTLEKQADGIFKLVTNKQTHYSKSVIITAGNGAFQPRRLELEGTAKYEKKNLHYFVDDMNKFAGKRVVVFGGGDSAVDWTMMLEPIADKVTIVHRRDKFRAHEHSVESLMNSRAEVSTPYVPVELIGDDKIEQVVLQHVKTEEKIIIDVDDVIVNYGFVSSLGPIKNWGLDIQKNSILVNSKMETNIPGIYAAGDICTYEGKVKLIACGFGEAPTAVNNAKAYFDPNAKLQPMHSSSMF
What are the official names of this protein?
Ferredoxin--NADP reductase 2, FNR 2, Fd-NADP(+) reductase 2.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: ISFD_CHRSD
Sequence: MTDCVFITGATSGFGRAAAHRFAAAGWSLVLTGRRLERLEALKEELQGRVPVHIIALDVRDSDVVDAAVAALPEGFTRVRTLLNNAGLALAPQSAQHTDRSDWHTMIDTNVTGLVNVTHALLPTLIDVGEGATIVNVGSIAGQWPYPGSHVYGASKAFVKQFSYNLRCDLLGTGVRVTDLAPGIAETEFTLVRTGGDQAASDALYRGTTALTAEDIAEQMFYIATLPPHVNFNRLEVMPTRQAWSAFAIDYDA
What is the function of this protein?
Catalyzes the formation of isethionate from 2-sulfoacetaldehyde in the deaminative pathway of taurine.  The enzyme is specific for NADPH; NADH is not a substrate.  Responsible for most of the activity observed in taurine-grown cells.
What are the official names of this protein?
Sulfoacetaldehyde reductase, Isethionate formation reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TPS1A_CAMHI
Sequence: MASSQVGDMVNGNAEPTRHLAKFPPSLWGDRFTSFTLDKQLWDKYGNEIEVLKEQVRSMVVAGGRKAAEQINLINVLERLGVSYHFEKEIEEQLEQLFAKFEDNEDYDLFTIALHFRIFRQHGYKMSCDVFNKFRDSNGEFKETVSNDVQGMLSLYEATYLKIRGEGFLDEAHAFTIAQLESLVGGPHLSSDLSEQVMHALKQSIHRGFPRLEAKHFISFYEKDASRNETLLRLAKLDFNQLQLSHREELCHIFRWWKELDLISKVPYARDRAVECFFWSTCAYYEPQHSVGRAVLTKIMLLLSVTDDTYDAYGTYDELKLYTNAVQRWDVSAMDELPDYMKALYRALLNVYDEVERDLAKQGRDYGVHHSKEAFKEIVRSYEIEAEWFKEGYVASFEEYMKNALVTSTGRLHTTSCFMGLEADVATTEAFEWILTKPKMVAASGAIGRLVDDVMSHDEEQERGHVATGLDCYMKQRGVSKQEAIVELYKMIENAWRDINEEMLKPTAISMKLLIRVLNLSRISDVVYKYVDGYTHPEIIKDHVISLFEDPIPM
What is the function of this protein?
Terpene synthase that catalyzes the biosynthesis of the terpene valerianol, which is a volatile compound of floral scent.
What are the official names of this protein?
Valerianol synthase TPS1A, Terpene synthase 1, ChTPS1, Terpene synthase 1a, ChTps1a.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: ANPE_ZOAAM
Sequence: MKSVILTGLLFVLLCVDHMTASQSVVATQLIPMNSALTPVMMEGKVTNPIGIPFAEMSQMVGKQVNRPVAKGQTIMPNMVKTYAAGK
What is the function of this protein?
Contributes to protect fish blood from freezing at subzero sea water temperatures.  Lowers the blood freezing point.  Binds to nascent ice crystals and prevents further growth (By similarity).
What are the official names of this protein?
Ice-structuring protein C10, ISP C10, Antifreeze protein C10.
What is the protein family that this protein belongs to?
Belongs to the type-III AFP family.
What are the subcellular locations of this protein?
Secreted.
Protein: TTHY_PONAB
Sequence: MASHRLLLLCLAGLVFVSEAGPTGAGESKCPLMVKVLDAVRGSPAVNVAVNVFKRAADETWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFAANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
What is the function of this protein?
Thyroid hormone-binding protein.  Probably transports thyroxine from the bloodstream to the brain (By similarity).
What are the official names of this protein?
Transthyretin, Prealbumin.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family.
What are the subcellular locations of this protein?
Secreted.
Protein: COX2_SALSA
Sequence: MAHPSQLGFQDAASPVMEELLHFHDHALMIVLLISTLVLYIIVAMVSTKLTNKYILDSQEIEIVWTVLPAVILILIALPSLRILYLMDEINDPHLTIKAMGHQWYWSYEYTDYEDLGFDSYMVPTQDLTPGQFRLLETDHRMVVPVESPIRVLVSAEDVLHSWAVPSLGVKMDASPGRLNQTAFIASRPGVFYGQCSEICGANHSFMPIVVEAVPLEHFEKWSTMMLEDA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNFH_ECOLU
Sequence: MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRTDIDLTKNKVGIYSRPAKLSDTVHDGDRVEIYRPLIADPKELRRQRAEKSANK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: APY6_ARATH
Sequence: MRRSHARSRVKNSSSSKSDMDPIKFQIRSGNRAPSSSSTYTLTKPNSKHAKSNLLLTVGSISVVLGVLFLCYSILFSGGNLRGSLRYSVVIDGGSTGTRIHVFGYRIESGKPVFEFRGANYASLKLHPGLSAFADDPDGASVSLTELVEFAKGRVPKGMWIETEVRLMATAGMRLLELPVQEKILGVARRVLKSSGFLFRDEWASVISGSDEGVYAWVVANFALGSLGGDPLKTTGIVELGGASAQVTFVSSEPMPPEFSRTISFGNVTYNLYSHSFLHFGQNAAHDKLWGSLLSRDHNSAVEPTREKIFTDPCAPKGYNLDANTQKHLSGLLAEESRLSDSFQAGGNYSQCRSAALTILQDGNEKCSYQHCSIGSTFTPKLRGRFLATENFFYTSKFFGLGEKAWLSNMISAGERFCGEDWSKLRVKDPSLHEEDLLRYCFSSAYIVSLLHDTLGIPLDDERIGYANQAGDIPLDWALGAFIQQTATETSQHAASGNLHWFHALFSNHPKTLHYLIGIPILMTVLVYLVTKWRKPQLKTIYDLEKGRYIVTRIR
What is the function of this protein?
Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates (By similarity).  Involved in the regulation of pollen and anther development.
What are the official names of this protein?
Probable apyrase 6, AtAPY6, ATP-diphosphatase, ATP-diphosphohydrolase, Adenosine diphosphatase, ADPase, NTPDase, Nucleoside triphosphate diphosphohydrolase 6.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: ENGB_XANOR
Sequence: MSLLIEQARYHLSAHNARQLPDDGGYEVAFAGRSNAGKSSALNALTRQNALARVSKTPGRTQQLVFFQIQPERYLVDLPGYGYAKVPQDLQAHWQAFIDRYFRTREALRGLVVVMDIRHPLKDYDLQMLGYAAERGLPAHGLLTKADKLGRGQQMQTLQKVKKEVTSRFGDSVTVQTYSGQSRQGVDELRGIVGGWLGLIAEPLAEH
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RLMF_SACD2
Sequence: MHKSANSKTRKQSKGLHPRNIHRNGYDFDALKACHPPLVQYIKCNPVGAATIDFANSAAVKALNTALLQHHYKIESWSIPDGALCPPIPGRIDYIHYIAELLGCPLPSGKINTANTCTNNAVKMLDVGTGANGIYTLLACAVYGWRCVGSDINSESLANVKAVLANNPTLNANISLRLQPNKDAFFSQIIQTDDYFDVSVCNPPFHASQEEASKGTNRKLHNLARSRNKAHTAKQPSLNFGGQHAELWCNGGERLFLKKMIKESQAFAQQVGWFTSLVSKSENVQPALKLIRKLGATEVREIEMMQGNKKTRVIAWRFKP
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_PARD8
Sequence: MKNIRNFCIIAHIDHGKSTLADRLLEYTKTVEGKDMQAQVLDDMDLERERGITIKSHAIQMKYNYKGEEYILNLIDTPGHVDFSYEVSRSIAACEGALLIVDAAQGIQAQTISNLYMAIENDLEIIPVMNKIDLPSAMPEEVEDQIVELLGCPREDILRASGKTGEGVTEILNTIVEKVPAPKGDPEAPLQCLIFDSVFNPFRGIIAYFKVVNGVIRKGDHVKFIATGKEYDADEVGILKLDMCPREEIRTGDVGYIISGIKTSREVRVGDTITHVSRPAKDAIAGFEEVKPMVFAGVYPIDSEDFENLRASLEKLQLNDASLTFQPESSAALGFGFRCGFLGLLHMEIVQERLDREFNMDVITTVPNVSYIVHTKKGEEIEVHNPGGLPDPTLIDHIDEPFIRASVITNTTYIGPIMTLCLGKRGVLLKQEYISGDRVEIHYDLPLGEIVIDFYDKLKSISKGYASFDYHLHDFRPSKLAKLDILLNGEPVDALSTLTHVDNSVTFGRRMCEKLKELIPRQQFDIAIQAAIGAKIIARETIKAVRKDVTAKCYGGDISRKRKLLEKQKEGKKRMKQIGTVEVPQKAFLAVLKLD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YOBD_SHIFL
Sequence: MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGRIDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRIPKIIFKQKGFFFANVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSGNAANLLI
What are the official names of this protein?
UPF0266 membrane protein YobD.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APO1B_PONAB
Sequence: MRLFLSLPVLVVVLSMVLEGPAPAQGAPDVSSALDKLKEFGNTLEDKAREVINRIKQSELSAKTR
What are the official names of this protein?
Apolipoprotein C-I, basic form, Apo-CIB, ApoC-IB, Apolipoprotein C1B.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: B3G5B_DANRE
Sequence: MAVLKMPRFKKYHLRLMITCFSTLLLMTYWEKIDNCVVTHVMSFSYRYLFNSFKFINSSFIVNPEDAIKYNHRYLINHQTKCDNKDILLLLFVKSSSENFERRQAIRSTWGNETYIESTLGVTVKVLFALGLHPIPEERGKLKEDLMFEDQKYRDLIQQDFIDTFHNLTLKLLLQLGWKETYCHHAQFLMSADDDVFVHTPNLILYLQGFGQSNTRDLWIGGVHRGSPPNRDKESKYYVSRDLYPWLSYPDYTPGSGYVLSRDVVSRIYQASLTINASFHIDDVFLGICAKMMDVSPTDHAFFSGEGKAPHHHCIYSLMMTSHGHVSDIHEMWRHARNAEDVLISSGLFRRLYCTAVKVRLLCVPFFSNSYPCKAAFFEEDT
What is the function of this protein?
Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids.
What are the official names of this protein?
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase B, Lactotriaosylceramide synthase B, Lc(3)Cer synthase B, Lc3 synthase B, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5B, BGnT-5B, Beta-1,3-Gn-T5B, Beta-1,3-N-acetylglucosaminyltransferase 5B, Beta3Gn-T5B.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: GET1_KOMPG
Sequence: MDPFSILLTLTLIILAQNAVRIVGKSQIHQSIWNLYLRYSNDQQILKLRNLKAESYDVYKQRSNTSAQDEYAKWTKLNRKYDQLQTEIKAVSDQVSQQQQAIEKYLGLAISVTTTLPLWLFRFKYRKQPLFYFPKDTFPSYLEWILSFPSVPQGSIGIMFWILLLNKFVSNLEFIVKTFSTKVEKPVPIVKVEDLSPK
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: SMYD4_MOUSE
Sequence: MDLPVDEWKSYLLKKWASLPKSVQDTISTAETLSDIFLPSSSLLQPEDEMFLKELSSSYSVEKDNDAPLFYREEGNRKFQEKEYTDAAVLYSKGVSHSRPNTEDISLCYANRSAALFHLGQYEACLKDIVEAGMHGYPERLQPKMMVRKTECLVNLGRLQEARQTISDLESSLTAKPTLVLSSYQILQRNVQHLKIKIQEKETLPEPIPAALTNAFEDIALGEENTQISGASLSVSLCTHPLKGRHLVATKDILPGELLVKEDAFVSVLIPGEMPRPHHCLENKWDTRVTSGDLYCHRCLKHTLATVPCGSCSYAKYCSQECMQQAWDLYHSTECSLGGLLLTLGVFCHVALRMTLLARFEDVDRVVRMLCDEVGSTDTCLPESKNLVKAFDYTSQGESEEKSKIGEPPIPGCNVNGKYGSNYNAIFSLLPHTEKHSPEHRFICAISVSALCRQLKADSVQAQTLKSPKLKAVTPGLCADLTVWGAAMLRHMLQLQCNAQAITSICHTGSNESIITNSRQIRLATGIFPVVSLLNHSCRPNTSVSFTGTVATVRAAQRIAKGQEILHCYGPHESRMGVAERQQRLSSQYFFDCRCGACHAETLRAAAAPRWEAFCCKTCRALMQGNDVLSCSNESCTNSVSRDQLVSRLQDLQQQVCMAQKLLRTGKPEQAIQQLLRCREAAESFLSAEHTVLGEIEDGLAQAHATLGNWLKSAAHVQKSLQVVETRHGPSSVEIGHELFKLAQVLFNGLAVPEALSAIWKAERILLVHCGPESEEVRELREMRSCLLDSSFVPVGPLV
What is the function of this protein?
Plays a critical role in cardiac development (By similarity).  Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1 (By similarity).
What are the official names of this protein?
SET and MYND domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.