PharMolix/UniProtQA huggingface dataset:
Protein: EUC1_YEAST
Sequence: MPAREYNYVEGFGGYGSLDDDDSDRDSERRNHDLGQRTITTSPTGVSRHAALNRYMIPGRINPLFRPTDAAQPPIVSTSTSASATEPTNRIGPGRIKETPETNFNAFLIAQLTRMEEQNANLKEEISLMKKEQELFFLENQKKLEKGFKDINKYVEDVSAMKEVFKEVVGIMTGERIRFIDHTGENVTPQEAARVGNPSTSTQAHQSQSRSTNWQEYSMHASILAGDPRIKPEPGLSDFENGEYDGNESDENATTRNLPLNNPDSVSNADDSNNQLDGTGNENDIRNRRGCVGTSYKLNRAIQNVTDAAREYFEGLPGQPSVLSLERRYGSTWRRSAKERTLFTKRMTIIKRIIDIKDDPSKYGLSLPENKISRNQAIKVVENIRLGNNTFKGHHCRLSMSQLYEYFSKKMDKLEDYSLTLKRRGKPRRIFLLEEREARLSLQQPHSIPNSSTGTPEHDQDT
What is the function of this protein?
Transcription factor-like protein that binds to specific DNA motifs called ub-HS-motif associated with several locations where proteins other than histone H2B are ubiquitinated (ub-hotspots) (PubMed:31015336).  Ubiquitination at these sites depends on the SUMO-targeted ubiquitin ligase (STUbL) complex SLX5/SLX8 and protein turnover on the CDC48 segregase (PubMed:31015336).  UBC9, SIZ1, or SIZ2 sumoylate DNA-bound EUC1 to stabilize its DNA-binding (PubMed:31015336).  Sumoylated EUC1 acts a cofactor required for the recruitment of the SLX5/SLX8 STUbL complex via specific contacts between EUC1 and SLX5, as well as an additional SUMO-mediated interaction (PubMed:31015336).  SLX5/SLX8 then ubiquitinates EUC1 and presumably other targets at ub-hotspots, and the CDC48/UFD1/NPL4 complex, together with UBX4 and UBX5, removes Lys-48-linked ubiquitinated proteins from chromatin.  Ubiquitinated proteins could be either degraded by the proteasome or recycled by deubiquitination (PubMed:31015336).  EUC1 itself does not seem to underlie extensive turnover, as it is a very stable protein (PubMed:31015336).  EUC1 is able to act as a transcription factor, but its function at ub-hotspots does not seem to depend on this ability (PubMed:31015336).  EUC1-mediated ub-hotspots are crucial during stress responses when gene expression control is impaired (PubMed:31015336).
What are the official names of this protein?
Transcription factor-like protein EUC1, Enriches ubiquitin on chromatin protein 1.
What are the subcellular locations of this protein?
Chromosome. Note=Localizes to few distinct genomic hotspots where proteins other than histone H2B are ubiquitinated (ub-hotspots).
Protein: PTR12_ARATH
Sequence: MEVEMHGDVSKWEGYADWRNKAALRGRHGGMLAASFVLAVEILENLAFLANASNLVLYLKNFMHMSLARSSSEVTTFMATAFLLALLGGFLADAFFSTFVIFLISASIEFLGLILLTIQARRPSLMPPPCKSSAALRCEVVGGSKAAFLFVGLYLVSLGIGGIKGSLPSHGAEQFDEGTPKGRKQRSTFFNYYVFCLSCGALVAVTFVVWIEDNKGWEWGFGVSTISIFLSILVFLLGSRFYKNKIPRGSPLTTIFKVLLAASIVSCSSKTSSNHFTSREVQSEHEEKTPSQSLTNSLTCLNKAIEGKTHHIWLECTVQQVEDVKIVLKMLPIFGCTIMLNCCLAQLSTYSVHQAATMNRKIVNFNVPSASLPVFPVVFMLILAPTYDHLIIPFARKVTKSEIGITHLQRIGVGLVLSIVAMAVAALVELKRKQVAREAGLLDSEETLPITFLWIALQYLFLGSADLFTLAGLLEFFFTEAPSSMRSLATSLSWASLALGYYLSSVMVPIVNRVTKSAGQSPWLGEKLNRNRLDLFYWLMCVLSVVNFLHYLFWAKRYKYISTGSIS
What is the function of this protein?
Involved in abscisic acid transport.
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 4.5, AtNPF4.5, Protein ABA-IMPORTING TRANSPORTER 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y2281_MYCTU
Sequence: MSDNAKHHRDGHLVASGLQDRAARTPQHEGFLGPDRPWHLSFSLLLAGSFVLFSWWAFDYAGSGANKVILVLATVVGMFMAFNVGGNDVANSFGTSVGAGTLTMKQALLVAAIFEVSGAVIAGGDVTETIRSGIVDLSGVSVDPRDFMNIMLSALSAAALWLLFANRMGYPVSTTHSIIGGIVGAAIALGMVSGQGGAALRMVQWDQIGQIVVSWVLSPVLGGLVSYLLYGVIKRHILLYNEQAERRLTEIKKERIAHRERHKAAFDRLTEIQQIAYTGALARDAVAANRKDFDPDELESDYYRELHEIDAKTSSVDAFRALQNWVPLVAAAGSMIIVAMLLFKGFKHMHLGLTTMNNYFIIAMVGAAVWMATFIFAKTLRGESLSRSTFLMFSWMQVFTASGFAFSHGSNDIANAIGPFAAILDVLRTGAIEGNAAVPAAAMVTFGVALCAGLWFIGRRVIATVGHNLTTMHPASGFAAELSAAGVVMGATVLGLPVSSTHILIGAVLGVGIVNRSTNWGLMKPIVLAWVITLPSAAILASVGLVALRAIF
What is the function of this protein?
Potential transporter for phosphate.
What are the official names of this protein?
Putative phosphate permease Rv2281.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURC_BRUO2
Sequence: MKMPLNIGLVHFIGIGGIGMSGIAEVLHNLGYKVQGSDQSDSANVQRLREKGIEVFVGHKAENLGDAEVIVVSTAIKKNNPELVAAREKLLPVVRRAEMLAELMRFRRAVAIGGTHGKTTTTSLVAALLDAGHLDPTVINGGIINAYGTNARMGDGDWMVVEADESDGTFLKLPADIAVVTNIDPEHLDHYGNFDAVRAAFRQFVENVPFYGFGVMCLDHPEVQALVSRIEDRRIITYGSNPQAEVRFVNQRMDGAASLFDVVIRSRKGEATEIKDLRLPMPGLHNVSNATAAIAVAHELGISSDDIRRGLGSFGGVKRRFTHTGSWNGVEIFDDYGHHPVEIRAVLKAAREATSQAGGRVVAIVQPHRYTRLASLFDEFAACFNDADTVIVAPVYTAGEEPIEGVNSEELVSRIKTAGHRDARYATGPEALAPLVASIAQAGDFVVCLGAGNVTQWAYALPKELAEQGKK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_SHEPA
Sequence: MGRIIGIDLGTTNSCVAVLDGDKARVLENAEGDRTTPSIIAYTADETLVGQSAKRQAVTNPTNTVFAIKRLIGRRFKDDEVQRDVDIMPFKIISADNGDAWVEAQGRKMAPPQISAEILKKMKKTAEDFLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAYGIDKKQGDNIVAVYDLGGGTFDISIIEIDSVDGEQTFEVLATNGDTHLGGEDFDNRMIKYLADEFKKEQGLDLRNDPLAMQRLKEAAEKAKIELSSTTQTEVNLPYITADATGPKHLVVKITRAKLESLVEDLIKRSLEPLKVALADADLSVSDINEVILVGGQTRMPKVREEVSAFFGKELRQDVNPDEAVAIGAAVQAGVLSGDVKDVLLLDVTPLSLGIETMGSVMTKLIEKNTTIPTKASQTFSTADDNQSAVTIHVLQGERKQSSGNKSLGQFNLEGIEAAPRGMPQIEVAFDIDADGILHVSATDKKTGKAQNITIKASSGLSDEEVEAMVRDAEAHADEDAKFEELVQARNQADGMVHGTKKQIEEAGEALPADEKEKIEAAMANVETAVKGNDKEAIEKSTQELMEASAKLMEIAQAKAQAQQGQPEGEAKAAKQDDDVVDAEFEEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RPOA_MYCS5
Sequence: MEKLTKIKHRIIPAKDSQNNSYKKVLKIKGLERGFGNTLAVALRRILLSNITGIAPFCVRIEGVEHEFTALEKVSEDIVTILSNLKKVVLNYDEDYVKDNQIIKLSLNANEDNRITSNHLTVTNAPRVEVQNKDVEIATLSKPGVLKLEMFLRAGRGYVDFEDNKKFIEEKEKELKELSSLSKGAFIAMDSVFSPVVNVAWKVTELNTASLKIEEQLELELETKLGVTPESAIKLACKILVAHFQTIGDLTDLDSDEIFQSEKQSLEKEEDDMEIRLLNLSMRSQNALAKSGIKTLNELASYPIEKLKEIKNLGEKSREEIIRKLNEYGKLKN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL13_BURMS
Sequence: MKTFSAKAHEVTREWYVIDATDKVLGRVASEVARRLRGKHKPEFTPHVDTGDFIIVINASKLKVTGNKTLDKKYYRHSGYPGGIYETTFGKMQERFPGRALEKAVKGMLPKCPLGYAMIKKLKVYAEATHPHSAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: KHSE_RHILO
Sequence: MAVYTDVAEGELGAFLKHYPVGDLLSYKGIAEGTENSNFLLHTSSGSYILTLYEKRVEKADLPFFLGLMGHLANKGVSCPLPVTAHDGSVIGTLAGRPAVIITFLEGLSLRRPTATHCAEVGKALAALHLAGADFPMTRPNALAIDGWRKLWNAARDRADEVEPGLAAEVDADFADFERNWPRGLPAGIIHADLFPDNVFFLGEKLSGLIDFYFACDDLYAYDVATCLNAWCFEKDFSFNLTKGKALLAGYQSVRPLSGEEKAALPMLSRGSALRFMLTRLYDWLTVSDGGLVMKRDPTEYIRRMRFHRAIKSASEYGLA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: RACK1_CHICK
Sequence: MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR
What is the function of this protein?
Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules.  Interacts with a wide variety of proteins and plays a role in many cellular processes (By similarity).
What are the official names of this protein?
Receptor of activated protein C kinase 1, Guanine nucleotide-binding protein subunit beta-like protein 12.3, Receptor for activated C kinase, Receptor of activated protein kinase C 1, RACK1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Perikaryon. Cell projection, dendrite. Note=Recruited to the plasma membrane through interaction with KRT1 which binds to membrane-bound ITGB1. Also associated with the membrane in oncogene-transformed cells. PKC activation induces translocation from the perinuclear region to the cell periphery (By similarity). In the brain, detected mainly in cell bodies and dendrites with little expression in axonal fibers or nuclei (By similarity).
Protein: AR2BP_HUMAN
Sequence: MDALEGESFALSFSSASDAEFDAVVGYLEDIIMDDEFQLLQRNFMDKYYLEFEDTEENKLIYTPIFNEYISLVEKYIEEQLLQRIPEFNMAAFTTTLQHHKDEVAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRGLDLSSGLVVTSLCKSSSLPASQNNLRH
What is the function of this protein?
Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3.  May play a role as an effector of ARL2.
What are the official names of this protein?
ADP-ribosylation factor-like protein 2-binding protein, ARF-like 2-binding protein, ARL2-binding protein, Binder of ARF2 protein 1.
What is the protein family that this protein belongs to?
Belongs to the ARL2BP family.
Protein: NLP9_ARATH
Sequence: MENPSASRDNKGFCFPDIPVEEMDGWVKNLISEEDMFSSSSTSELMNFESFASWCNSPSAADILFTQYGLSTSQSIIPFGGLEGSYACEKRPLDCTSVPRSLSHSLDEKMLKALSLFMEFSGEGILAQFWTPIKTGDQYMLSTCDQAYLLDSRLSGYREASRRFTFSAEANQCSYPGLPGRVFISGVPEWTSNVMYYKTAEYLRMKHALDNEVRGSIAIPVLEASGSSCCAVLELVTCREKPNFDVEMNSVCRALQAVNLQTSTIPRRQYLSSNQKEALAEIRDVLRAVCYAHRLPLALAWIPCSYSKGANDELVKVYGKNSKECSLLCIEETSCYVNDMEMEGFVNACLEHYLREGQGIVGKALISNKPSFSSDVKTFDICEYPLVQHARKFGLNAAVATKLRSTFTGDNDYILEFFLPVSMKGSSEQQLLLDSLSGTMQRLCRTLKTVSDAESIDGTEFGSRSVEMTNLPQATVSVGSFHTTFLDTDVNSTRSTFSNISSNKRNEMAGSQGTLQQEISGARRLEKKKSSTEKNVSLNVLQQYFSGSLKDAAKSLGVCPTTLKRICRQHGIMRWPSRKINKVNRSLRKIQTVLDSVQGVEGGLKFDSVTGEFVAVGPFIQEFGTQKSLSSHDEDALARSQGDMDEDVSVEPLEVKSHDGGGVKLEEDVETNHQAGPGSLKKPWTWISKQSGLIYSDDTDIGKRSEEVNKDKEDLCVRRCLSSVALAGDGMNTRIERGNGTVEPNHSISSSMSDSSNSSGAVLLGSSSASLEQNWNQIRTHNNSGESGSSSTLTVKATYREDTVRFKLDPYVVGCSQLYREVAKRFKLQEGAFQLKYLDDEEEWVMLVTDSDLHECFEILNGMRKHTVKFLVRDIPNTAMGSSAGSNGYLGTGT
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Protein NLP9, AtNLP9, NIN-like protein 9, Nodule inception protein-like protein 8.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLSX_ECO24
Sequence: MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDAITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRVALELVKEGRAQACVSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQFAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEANELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKSLTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAARLESVYPAGFELLDGGKSGTLR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MUSK_MOUSE
Sequence: MRELVNIPLLQMLTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCIANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDNALRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKLVKLEVEVFARILRAPESHNVTFGSFVTLRCTAIGIPVPTISWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATVSIAEWSKSQKDSQGYCAQYRGEVCDAVLAKDALVFFNTSYRDPEDAQELLIHTAWNELKAVSPLCRPAAEALLCNHLFQECSPGVVPTPMPICREYCLAVKELFCAKEWQAMEGKAHRGLYRSGMHLLPVPECSKLPSMHRDPTACTRLPYLDYKKENITTFPSITSSRPSADIPNLPASTSSFAVSPAYSMTVIISIVSSFALFALLTIATLYCCRRRKEWKNKKRESTAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSTRARVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGETMVVKIADFGLSRNIYSADYYKADGNDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILACPENCPLELYNLMRLCWSKLPADRPSFCSIHRILQRMCERAEGTVGV
What is the function of this protein?
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle.  Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex.  The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane.  May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK.  DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering.  May positively regulate Rho family GTPases through FNTA.  Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression.  Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK.  May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation.
What are the official names of this protein?
Muscle, skeletal receptor tyrosine-protein kinase, Muscle-specific tyrosine-protein kinase receptor, MuSK, Muscle-specific kinase receptor.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Single-pass type I membrane protein. Note=Localizes to the postsynaptic cell membrane of the neuromuscular junction.
Protein: Y1219_RICCN
Sequence: MSWIIFYTVIAALLILDLRIIHKNNTIMSFKESVLFSLFYLVIACLFGIYVYYNTGADHAREYYTCFLIEKAMSLDNIFVISIIFQFFKIPWQYQHRVLFFGIIGVIIFRAVMIYGGIILINKFAWLLYIFAVILIATGIKTFYVSHKTFDIQNSYIYKSIIKNLNITPNLEGNKFIVKRNNKLYCTPLFISLVLIEAIDLVFAIDSIPAIFAITNDVYIIYTSNIFAILGLRALFFCLAEIVERFSYIKYSLALILIFISFKIFIHHYIAIPEYVAFTVTMTLLLFGIIASIIRKNMIDH
What are the official names of this protein?
Uncharacterized membrane protein RC1219.
What is the protein family that this protein belongs to?
Belongs to the TerC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM3_BURP0
Sequence: MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAERAVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRRVSDALERQGARAIVDALVAASAQAQKGGA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RL10_STAA9
Sequence: MSAIIEAKKQLVDEIAEVLSNSVSTVIVDYRGLTVAEVTDLRSQLREAGVEYKVYKNTMVRRAAEKAGIEGLDEFLTGPTAIATSSEDAVAAAKVISGFAKDHEALEIKSGVMEGNVITAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAIGEQKEENAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PYRG_MYCSS
Sequence: MPALRKHPQTATKHLFVTGGVVSSLGKGLTGSSLGQLLTARGLQVTMQKLDPYLNVDPGTMNPFQHGEVFVTEDGAETDLDVGHYERFLDRNLSGSANVTTGQIYSSVIAKERRGEYLGDTVQVIPHITDEIKSRILAMAAPDEHGNRPDVVITEVGGTVGDIESLPFLEAARQVRHEVGRENCFFLHCSLVPYMAPSGELKTKPTQHSVAALRSIGIQPDALILRCDRDVPEALKNKIALMCDVDIDGVISTPDAPSIYDIPKVLHREELDAYVVRRLNLPFRDVDWTQWNDLLKRVHEPHETVRIALVGKYIDLSDAYLSVTEALRAGGFFHHAKVEMRWVASDDCELDSGAAAALADVDGVLIPGGFGIRGIEGKIGAISYARKRGLPVLGLCLGLQCIVIEAARSVGITGANSAEFDPATPDPVISTMADQRDAVAGAADLGGTMRLGAYPAVLEEDSIVARAYQATEVSERHRHRYEVNNAYRDRIAESGLRFSGTSPDGHLVEFVEYDAEQHPFLVGTQAHPELKSRPTRPHPLFAAFIGAALDYKAAERLPVEIPEQRSNGVELLQEPASRG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NUON_BACAN
Sequence: MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFVTLFVGLELLSLSSYILVGIRKKNRASNEAAMKYVINGGIGTAITLFGMSYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMIIGNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSNKENITIFTGLYKRSPFTAIVMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIVPMIGYNFFYEYFPLMKDFFFLGNVVQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FBPC_YERPE
Sequence: MSTLELHHIGKSYQSVMVLDRIDLHVPPGSRTAIVGPSGSGKTTLLRIIAGFETPDAGKVILQGKAMFDGTTYVPAHKRGIGFVPQDGALFPHFTVAGNIGYGLKGSQRDKERRINELMDMVALDRRLSALWPHEISGGQQQRVALARALAQRPVLMLLDEPFSALDTALRASTRKAVAELLSEANIASILVTHDQTEALSFADQVAVMRAGKLAHVGPPQELYLRPVDEPTATFLGETLMLTAQLGTGLAHCALGQVKVDNPHRRGEARIMLRPEQITLTPLRPEQYNAASCLAKVIAIDFAGFISTLTLQIISSGETIEIKTISREDLHVGLTVGLDIMGQAHIFAE
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPD_STRSV
Sequence: MKEIIAKLADFKDLSSAEMTDVIERIVTGRVTESQIVAFLLGLKMKGETIEERTALAQVMRGHAKQIPTTIRTAMDNCGTGGDKSFSFNISTTAAFVLAGGGIKMAKHGNRSISSKSGSADVLEALGINLDLDAASLGKVFEQTGIVFLFAKNMHPAMKYIMPARLSLGIPTIMNLTGPLIHPMSLETQLLGTSRPDMLESTAEVLKNMGRKRAVVVSGPDGLDEAGLHGRTQYALLADGQISLHSFLPSDIGMEEISLEVIRGGNAKENAEILLSVLQNQASPYLETTVLNAGLGFYANGKSDSIEEGIALARQVIASGVAYEKLKQLQEYQK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RECR_ERWT9
Sequence: MQTSPLLETLMESLRCLPGVGPKSAQRMAFQLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEICTICANPRRQHNGLICVVESPADIHAIEQTGQFSGRYFVLMGHLSPLDGIGPGDIGLDRLEQRLETESIQEVILATNPTVEGEATANYIASLCEQYGVDASRIAHGVPVGGELEMVDGTTLSHSLAGRQKFKF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PUR7_ACTSZ
Sequence: MAELSLKKIYSGKVRDLYEIDDKRMLMVASDRLSAFDVILDDPIPHKGEILTQISNFWFKKLAHIMPNHFTGDSVYDVLPKAEADLLKDRAVVVKRLKPIKIESIVRGYLTGSGLKDYQQTGTICGLELPKGLVEAGKLPEPIFTPSSKEEVGDHDINISYAECERLIGKELAAQVRDAAIALYKEAAAYALTKGIIICDTKFEFGLDENGTLTLMDEVLTPDSSRFWSVDTYKEGTNPPSFDKQFVRDWLEQSGWNKQPPAPKVPAEVIEKTVAKYQEALDLLTK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: LP412_MYCIP
Sequence: MRNRTVAAGAVLTAALLGACTSHPPTHISSTASVTVNGHDRTFHIVKCGQVQWTRMIDIGSEFSGAKVVVDENAQPATTQSVRIRNVGGFSGMYSQGGDGNADMSMTGDKFTVSGTANGYQTDKPSEPAAATFKIVVTC
What are the official names of this protein?
Putative lipoprotein MIP_01412.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial 19 kDa antigen family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TX33A_MACGS
Sequence: MKLSALVFVASVMLVAASPVKDVEEPVETHLAADLKTIEELAKYEEAAVQKRSCIVGSKNIGETCVASCQCCGATVRCIGEGTKGICNNYQTNNILGQILLYAKDTVVNTAGLLVCAQDLSEYE
What is the function of this protein?
No toxicity is observed upon intracranial injection into mice and intrathorax injection into crickets.
What are the official names of this protein?
U13-hexatoxin-Mg1a, U13-HXTX-Mg1a, Neurotoxin magi-12.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_SALNS
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.