PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_LIMF3
Sequence: MNLVPTVIEQSSRGERAYDIYSRLLKDRIIMLSGPIEDNMANSIVAQLLFLDAQDSTKDIYLYINSPGGVVTSGMAIYDTMNFIKSDVQTIVIGMAASMASVLVSSGTKGKRFGLPHSTVMIHQPSGGAQGQQTEIQIAAEEILKTRKMINEILAKNSGQSFEQVEQDTERDHYLTAQEAVDYGLLDGVMDSNNLK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_NEIMA
Sequence: MSEQNHPQTEPQLDENQIIALRREKLHNIRQQRNAYPNDFKRDSFAADLHAQYGEIGKEELDPQGIPVKVAGRMMLKRQMGKASFATIQDVSGQIQLYLNNKGVSQEVLDDFNHWDLGDIVGAEGTLFKTNHGELTVRVSGIRLLSKSLRPLPDKHKGLSDQETKYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMMHPIPGGATAKPFVTHHNALDIPLYLRIAPELYLKRLVVGGLERVFEINRSFRNEGMSVRHNPEFTMIEFYEAFSDYERMMQMAEDIIRNASHTVNGTANITYNGKEVDLESPFERLTILEAIKKYNPHYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVSPLARASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKAQVAQKDAGDDEAMHYDADYIRAMEFGLPPTGGCGIGIDRLVMLLTDSQTIRDVILFPQMRPE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAL1_ASPNC
Sequence: MADGIDRRADDRMEFNTSKEVTVAPTFEDMHLKESLLRGIYAYGYESPSAVQSRAIVQICKGRDTIAQAQSGTGKTATFSISILQVIDTVVRESQALVLSPTRELATQIQSVIMALGDYMNVQCHACIGGTNIGEDIRKLDYGQHVVSGTPGRVADMIRRRHLRTRHIKMLVLDEADELLNRGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRVLVKRDELTLEGIKQYFIAVEKEEWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGEMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPTNRENYIHRIGRSGRFGRKGVAINFVTSDDVRILRDIELYYSTQIDEMPMNVADLLS
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase fal1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: URE32_PSYCK
Sequence: MQLNPTEKDKLLLFTAGMVAERRKNRGVKLNYPESIAYISMLLMEGARDGKTVAQLMSEGATYLSANDVMEGIAEMIHDVQVEATFPDGTKLVTVHNPIV
What are the official names of this protein?
Urease subunit gamma 2, Urea amidohydrolase subunit gamma 2.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFLT_ASPPU
Sequence: MLIDEAAEASSHISGMKLYLIVLSLLLAVFCVALDNTILSVAIPRITDEFHRLNDIGWYASAYLLTTCAFQLLYGKLYALFSTKWVFLVALCIFEVGSLICGVAPSSVVLIVGRAIAGVGSSGIFTGALVTIAHIVPLAKRPVYMGLLGGMYGIASVAGPLLGGAFTNEVTWRWCFYINLPVGGVTAVVILFLLRIPKSADLRTHGAWEMLKGLDPLGTIVFTPSIICVLLALQWGGVDYAWSNGRIIALFVLFGVLLITFIIIQVLMKDKATVPIKVASQRSVACASVFVFFIGASMFVMIYYVPIWFQAIRNQSPVQAGIDSIALILANTAGAIISGAVTNKTGHYAPWFIVSSVIMSIGAGCLTLFTVDIAQSKWIGFLFLYGIGVGFGFQQGAVAVQAVLPMAQVPIGTALIWFVQMLGGALFTSVAQNIFSTHLAENLANLQLPGLDPEAIVGAGATGFRQLVQPEYMDQVLVAYNAALLDVFQVALICSCLSILGAVGIEWRSVKQNR
What is the function of this protein?
Efflux pump; part of the gene cluster that mediates the biosynthesis of aflatoxins (PubMed:15006741, PubMed:15094053).
What are the official names of this protein?
Efflux pump aflT, Aflatoxin biosynthesis protein T.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL2_SHEAM
Sequence: MAIVKCKPTSPGRRGVVKIVNSDLHKGKPFAGLLAKKSKTGGRNNTGRITTRHVGGGHKQHYRLIDFKRNKDGIPGKIERLEYDPNRTANIALVLYADGERRYILAAKGMQAGDKVVSGIDADIKVGNALPLRNIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVARDGEYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGVPTKGYKTRSNKRTDKYIVRRRTK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GRDB_PEPLI
Sequence: MGKLRVVHYINQFFAGIGGEEKADIAPFVAEELPPISQNLDKLLGEDAEVVATVVCGDSFFGENLETAQATVLEMVKGASPDLFIAGPAFNAGRYGVAAGAITKAVQDTLGIPAVTGMYIENPGADMYKKSVYVMSTADSAAGMRKSLPALAKFALKYAKGEEIGSPAEEGYIERGIRVNGFKEDRGAKRAVAMLVKKLKGEEFVTEYPMPVFDNVVPGRAIVNMSKAKIAIVTSGGIVPKGNPDRIESSSASKYGKYDIDGVDDLTSEGWETAHGGHDPVYANEDADRVIPVDVLRDMEKEGVIGELHRYFYSTTGNGTAVLSSKQFAKEFTQELMAAGVDAVILTSTUGTCTRCGATMVKEIERSGIPVVHICTVTPIALTVGANRIVPAIAIPHPLGDPALSPAEEKALRRKIVEKSLKALETEIEEQTVFED
What is the function of this protein?
In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate.  Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine.  By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state.  Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
What are the official names of this protein?
Glycine reductase complex component B subunit gamma, Selenoprotein PB gamma.
What is the protein family that this protein belongs to?
Belongs to the GrdB/GrdF/GrdH family.
Protein: COAA_ALKCK
Sequence: MTTDELTKSLEAFTHFTRAEWAQLNDGHSAPLTEKERKNLEGIYETISEAEVNDVYMPLSELLYKRMVHNVRLHDDLNRFLKRERKRVPFVIGIAGSVAVGKSTTARLIQALASRWPGSPKVELVTTDGFLYPNEVLEKRGLMKRKGFPESYDIRSLLTFLTDLKAGTPVVKAPMYSHLTYNIEKDHIQTLIEPDVVIVEGINVLQVNRKGKRMPHVFVSDFFDFSIYVDAEEKDILSWYIERFQLLRNTAFQKPESYFHRYRDLTDEEAVAMAESIWHTINGVNLEKNIKPTRLRADLILTKGAHHRVEQVQLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTE_SALTY
Sequence: MNQQDIEQVVKAVLLKMKDSSQPASTVHEMGVFASLDDAVAAAKRAQQGLKSVAMRQLAIHAIREAGEKHARELAELAVSETGMGRVDDKFAKNVAQARGTPGVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVVFAPHPAAKKVSQRAITLLNQAVVAAGGPENLLVTVANPDIETAQRLFKYPGIGLLVVTGGEAVVDAARKHTNKRLIAAGAGNPPVVVDETADLPRAAQSIVKGASFDNNIICADEKVLIVVDSVADELMRLMEGQHAVKLTAAQAEQLQPVLLKNIDERGKGTVSRDWVGRDAGKIAAAIGLNVPDQTRLLFVETPANHPFAVTEMMMPVLPVVRVANVEEAIALAVQLEGGCHHTAAMHSRNIDNMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV
What is the function of this protein?
Expression of the eut operon allows this bacteria to use ethanolamine (EA) as a carbon, nitrogen and energy source.  It relies on cobalamin (vitamin B12) both as a cofactor for the ethanolamine ammonia-lyase (EAL) activity and to induce the operon (PubMed:3045078).  EA enhances bacterial survival in macrophages in a concentration-dependent manner, suggesting it is an important nutrient during infection (PubMed:29531136).
What are the official names of this protein?
Acetaldehyde dehydrogenase (acetylating) EutE, Ethanolamine utilization protein EutE.
What is the protein family that this protein belongs to?
Belongs to the EutE/PduP family.
What are the subcellular locations of this protein?
Bacterial microcompartment. Note=Probably located inside the BMC.
Protein: KUP_CHLCH
Sequence: MKRLGGLALAALGVVFGDIGTSPLYAIRECFHGDYGIAINEANVFGVLSLLVWSLLLIVSLKYLTFIMKADNDGEGGILALTALLIRHCKKNGGSERFFLIAIGLFGAALLYGDGMITPAISVLSALEGVQMVAPAFHDLIIPATVTVLVILFLFQHHGTARVGTLFGPVILLWFVVLGVLGLVEILRYPQILQAFFPWHGIMFLLNNQLHGFMVLGAVFLSVTGAEALYADMGHFGKRPIRLTWAFLVLPALLLNYFGQGALLLDSPADAHHPFYGLVPSWGLIPMVILSTSATIIASQALITGVFSLTQQAIQLGYLPRLTVTHTSAKHMGQIYVPAANWSLMVATISLVIGFGSSSKLAAAYGVAVTATMLISTILFYYVARDLWRWNKSVLNVMIVVFLLVDLAFFGASASKLFHGAWFPLVIAAVMFTVMMTWKQGRGLLLKQLQDRTLTVEEFMSSLALQPPYRTNGQAVYLTANPDLVPLAMLHNLRHNKVLHSEVALFHFSTERVPRVPNNRKVEVVKLGDGFYKVVARYGFLEYPTIRQVLALANHQGLHFKPEAISFFLSREKIVAGVKSKMTIWRKKLFAVMSRNAISATSYYDLPPGQVIEIGLMVQI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRC_FUSNN
Sequence: MDIGKIDIPESSGVYLMKKNNKVIYVGKAKNLKNRVSSYFNRVHESEKTNELVKNIEDIEFFLTNTEIDALLLENNLIKKYSPKYNILLKDEKTYPFIKISKEDFSSIKIVRTTKALDIKSGEYFGPYPYGAWRLKNILMKLFKIRDCNRDMKKTSPRPCLKYYMKSCTGPCVYKDIKEEYNKDVENLKQVLKGNTSKLINELTALMNKASQDMDFEKSIIYREQIKELKSIASSQIIQYERELDEDIFVFKTILDKAFICVLNMRDGKILGKSSTSIDLKNKITDNIYEAIFMSYYSKHILPKSLVLDAEYENELSVVVKALTIEDSKKKEFHFPKIKSRRKELLDMAYKNLERDIESYFSKKDTIEKGIKDLHDILGLKRFPRKIECFDISNIQGKDAVASMSVSIEGRAARKEYRKFKIRCKDTPDDFSMMREVIERRYSKLPDIEFPDVILIDGGLGQINSAGEVLKRLGKIHLSELLSLAERNEEIYKYGESIPYVLSKDMEALKIFQRVRDEAHRFGITYHRKIRSKRIISSELDKIDGIGEVRRRKLLTKFGSISAIKKASIEELKEIIPEKVALEIKNKIR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_MYCPA
Sequence: MSSGILDELGWRGLIAQSTDLDALAAEARPMTVYAGFDPTAPSLHAGHLVPLLALRRFQRAGHRPIVLAGGATGMIGDPRDVGERTLNEADTVAEWTERIRGQLERFVDFDESDTGAVVVNNLDWTRQLSAIEFLRDLGKHFSVNVMLDRDTVRRRLEGDGISYTEFSYMLLQANDYVELHRRYGCVLQIGGSDQWGNIIAGVRLVRQKLGATVHALTVPLVTAADGTKFGKSTGGGSLWLDPALTTPYAWYQYFFNTADADVIRYLRWFTFLSADELGELERATAERPQQRAAQRRLARELTVLVHGEAATEAVKHASRALFGQGELERLDAATLAAALRETSVAELKPGAPDGIVDLLVASGLSESRKAARRTLGEGGVSVNNVRIDREDWAPQPSDFLHGKWLVLRRGKRTIAGVEKL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_MYCBO
Sequence: MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLAYAAYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_MARMM
Sequence: MPRYIFITGGVVSSLGKGLASAAIGALLQARGYKVRLRKLDPYLNVDPGTMSPYQHGECYVTDDGAEADLDLGHYERFTGVPASQADNITTGRIYSRIIERERRGDYLGATVQVIPHVTDQIKQFVLSDAGDVDFVLCEIGGTVGDIEGLPFFEAIRQLGQELGEGNAVFLHVTLLPFIKVAGEMKTKPTQHSVKELRSIGIQPDILLCRCEIPIPPGDKRKIGLFCNVKESAVIEGRDAASLYDVPLEYHSQGLDTEILRCFGIDDAPAPDLSRWQGISETIANPDGEVTIGVVGKYVGLLDAYKSLIEALAHGGIANGVKVKLKWLDSEQFEKDDPFEPLEDVHGVLVPGGFGERGVEGKIAAARFARERKVPFFGICYGMQMAVLEAARNLAGVTDAVSTEFSDTGESVIGLLTEWTRGNEVETRKVGDDMGGTMRLGAYPAVLKDGSKVREIYGQAHIEERHRHRYEVNVGYKDRLEACGLTFSGLSPDGVLPEIVEIEDHPWFIGVQFHPELKSRPFEPHPLFASFIAAALHQSRMV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: H2B_LEIEN
Sequence: MASQRLAPRKSSAAHKSHRKPKRSWNVYVSRSLKAINSHMSMSGRTMKIVNSYVNDVMERIAMEAASIVRAHKKLTLGAREVQTAVRLVLPPELAKHAMAEGTKAVSNSCR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ASPG_RAT
Sequence: MARKWNLPFLLLPLVLGIPLVRGSNPLPLVVNTWPFKNATEAAWWTLVSGGSALDAVEKGCAMCEKEQCGGTVGFGGSPDEVGETTLDAMIMDGTAMDVGAVGGLRRIKNAIGVARKVLEHTTHTLLVGDSATKFAVSMGFTSEDLSTNTSRALHSDWLSRNCQPNYWRNVIPDPSKYCGPYKPPDFLEQNNRAHKEVDIHSHDTIGMVVIHKTGHTAAGTSTNGLKFKIPGRVGDSPIPGAGAYADDMAGAAAATGDGDTLLRFLPSYQAVEYMRGGDDPARACQKVISRIQKYYPKFFGAVICANVTGSYGAACNRLPTFTQFSFMVYNSLHNQAIEEKVDCM
What is the function of this protein?
Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.
What are the official names of this protein?
N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase, Aspartylglucosaminidase, AGA, Glycosylasparaginase, N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: DNMT2_ARATH
Sequence: METKVGKQKKRSVDSNDDVSKERRPKRAAACRNFKEKPLRISDKSETVEAKKEQNVVEEIVAIQLTSSLESNDDPRPNRRLTDFVLHNSDGVPQPVEMLELGDIFLEGVVLPLGDDKNEEKGVRFQSFGRVENWNISGYEDGSPGIWISTALADYDCRKPASKYKKIYDYFFEKACACVEVFKSLSKNPDTSLDELLAAVARSMSGSKIFSSGGAIQEFVISQGEFIYNQLAGLDETAKNHETCFVENSVLVSLRDHESSKIHKALSNVALRIDESQLVKSDHLVDGAEAEDVRYAKLIQEEEYRISMERSRNKRSSTTSASNKFYIKINEHEIANDYPLPSYYKNTKEETDELLLFEPGYEVDTRDLPCRTLHNWALYNSDSRMISLEVLPMRPCAEIDVTVFGSGVVAEDDGSGFCLDDSESSTSTQSNVHDGMNIFLSQIKEWMIEFGAEMIFVTLRTDMAWYRLGKPSKQYAPWFETVMKTVRVAISIFNMLMRESRVAKLSYANVIKRLCGLEENDKAYISSKLLDVERYVVVHGQIILQLFEEYPDKDIKRCPFVTGLASKMQDIHHTKWIIKRKKKILQKGKNLNPRAGLAHVVTRMKPMQATTTRLVNRIWGEFYSIYSPEVPSEAIHEVEEEEIEEDEEEDENEEDDIEEEAVEVQKSHTPKKSRGNSEDMEIKWNGEILGETSDGEPLYGRALVGGETVAVGSAVILEVDDPDETPAIYFVEFMFESSDQCKMLHGKLLQRGSETVIGTAANERELFLTNECLTVHLKDIKGTVSLDIRSRPWGHQYRKENLVVDKLDRARAEERKANGLPTEYYCKSLYSPERGGFFSLPRNDIGLGSGFCSSCKIKEEEEERSKTKLNISKTGVFSNGIEYYNGDFVYVLPNYITKDGLKKGTSRRTTLKCGRNVGLKAFVVCQLLDVIVLEESRKASNASFQVKLTRFYRPEDISEEKAYASDIQELYYSHDTYILPPEALQGKCEVRKKNDMPLCREYPILDHIFFCEVFYDSSTGYLKQFPANMKLKFSTIKDETLLREKKGKGVETGTSSGILMKPDEVPKEMRLATLDIFAGCGGLSHGLEKAGVSNTKWAIEYEEPAGHAFKQNHPEATVFVDNCNVILRAIMEKCGDVDDCVSTVEAAELVAKLDENQKSTLPLPGQADFISGGPPCQGFSGMNRFSDGSWSKVQCEMILAFLSFADYFRPKYFLLENVKKFVTYNKGRTFQLTMASLLEIGYQVRFGILEAGTYGVSQPRKRVIIWAASPEEVLPEWPEPMHVFDNPGSKISLPRGLHYDTVRNTKFGAPFRSITVRDTIGDLPLVENGESKINKEYRTTPVSWFQKKIRGNMSVLTDHICKGLNELNLIRCKKIPKRPGADWRDLPDENVTLSNGLVEKLRPLALSKTAKNHNEWKGLYGRLDWQGNLPISITDPQPMGKVGMCFHPEQDRIITVRECARSQGFPDSYEFSGTTKHKHRQIGNAVPPPLAFALGRKLKEALYLKSSLQHQS
What is the function of this protein?
Maintains chromatin CpG methylation that plays a role in genomic imprinting, regulation of embryogenesis and seed viability.  Required for proper patterns of CG DNA methylation in dividing cells (By similarity).
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase 2, DNA methyltransferase 2, DNA methyltransferase IIb.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1708_HAEDU
Sequence: MEYQFTHSIHGIVAKCSMEHEVFARWLNTEIIGHTQNLHNILAEIEKCRAAFPNHYECVFEGQEYSLYFDCDEVIVKVNNLAMAIDEVIVEEGLQLYDQESVAFCGLEDFERFLQAYHKFSSTYH
What are the official names of this protein?
UPF0231 protein HD_1708.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: CLPB_LACLM
Sequence: MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDFTNLIEKEIDKINSVEGSNITYGQNLSPDLFQVFTEADKIAQKMGDEYLSTEIILLALFELKQNPLTEYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETYKALEKYGVDLVAQVKSGNQDPVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKYRGEFEERLKAVLNEVKKADGQIILFIDELHTIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFEIHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLIDEASATIRVEMNSLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNELEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQIAEVVGRMTGIPITKLVEGEREKLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRPLGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEYMEKHSVSRLVGAPPGYVGYDEGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMTSNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNIILKMTSQLAHRLEEMEVELELSEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIGGKIPPKSKVIVRLIDNKVDFDVQSIAE
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYI2_HELCR
Sequence: MPVKSTKTKGGSTQGGSQAGGPSTLKVNKARVPAKGKKDDDDATEAGEHGGEEWMQTKSLIKPDDQLELNDQELKEEFTRILTANNPHAPQNIVRYSFKDCSFKQTSHVDQLAIHFSLDGNMIHKDSDEARRQQQRHGASEAISEQAISEAGEEKKEEDGEQKTEEPKEGEKRDEESTPAPAEAKSDQKLTNQFNFSERASQTYNNPYRERGTQTEPPPRANFSSTANQWEIYDAYMEDLEKQEKAKEKKAAPSKKDDDKSKKKLTALETQSDDMSRISHAAKIIERMVNQNTFDDVSQDFKYYEDMSDEFRDQEGTLLPLWKFSYDKSKRLAVTSVCWNPKYKDLFAVAHGSYDFMKQSRGMILFYTLKNPSFPEFVYPTDSGVMCIDIRPEHPYLICVGYCDGSVGVFNVTSTDANPVFQSTAKTGKHTDPVWQVAWQKDDLDNNLNFFSVSSDGRVVAWTLVKNELTYTDVIQLQLDSAPQDGPEGTQLTPLGCGTCFDFHKQTDYLFLVGTEEGKIHKCSKAYSSQFLDTFEAHHMAVYKVMWNHFHPKIFISCSADWSVKIWDHTYRNGPMFTFDLGSAVGDVAWAPYSSTVFAAVTADGKVHVFDLNLNKYEPICEQAVVQKKKTKLTHITFNPNFPIVLVGDDRGYVSSLKLSPNLRKVPKDKKGAALNHGPEAEIAKMDKLLALVREPPKDNKS
What is the function of this protein?
Microtubule-binding protein that may be involved in dynein outer arm assembly on the axoneme.
What are the official names of this protein?
Dynein intermediate chain 2, ciliary.
What is the protein family that this protein belongs to?
Belongs to the dynein intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: ENGB_HYPNA
Sequence: MDAAAAPEFTEEALEAGRLLFAGKAEFVMGVVSLSGLPPADRSEVCFAGRSNVGKSSLINALTGRAKLARSSAEPGRTRELNYFDIGDEGKLYLVDLPGFGYAKVSKTQTAAWTKLIKSYLRGRPSLRRVFLLVDARRGDLMDTDEEVMDLMDGAAVTYQVVLTKVDKVPKGEVEKIVVKIADKLKKRGAAHPVVRMTSAEKGFGIPELRAEIAALAMLG
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: IML1_ASPOR
Sequence: MSLRGPMKHSHLRQVSAASLETLSTTRSLALSQTDGQSDKPSTPDERTIRLSSTGLDRRQCSLWVHDETFSKEEILFNQAAFTDMGVEVGDVIEILPARYPGDGTHSAKTDFGSRSLRDSHVESSSTLHSDSMSKFKTPLQSRCLFVVKPLPQDIKTRNPKLELSVTTSIANIFGFKNRTTVHISIVDRAQCAASHVDISFRDQYMVRSDMWRLVMSELAERIVYKGQKIVFTGSIKATVKNIFIRGKKVLSGFFSPQTIPVFRSESAKYVLFIQMSREMWDFDSEGTGDILFSRVINGFLPELFKRWVNSDARHLVTIVLFTRVEYDASAIASSTFSSENLTSMFGPNHVPTRDFYRVVVNDMASGHWTTILDELKKDFRTFLRDVSILNVHNADTPTFNATGASKSQPATIAGRPSTALRGNILEAIHLASSHLAFDHIDRDMVHTGTSIIVITPGSGVFEVSYESLASTTEALTNRGIAIDLVCLSPMPLHSVPLFKYREPAHRPTTAAFGDIQHGGYSPEMRHSFASISSKTPHLSPKSALLDSFTGMSSKSQWSGRSNEWNYGIPHWLDISYWNPETYRESRRILKKDPNAPIPFTVTKQSKVFVPRVRMYEIQMMGVMESEQSNISIPYLSEGPNISRATSSTLGSSPGSLVPPKATFRRNSPFRHQLSDSLRPEPFLHNMASSKDAMLTIPKKTPKTVLSWMDNYDENVFQPFRKRRHRRKPSKIKRPSEPEVKASNAHERISARSISRLRENESTRSASRQIDIPLPAPKSPVSTKSASPKKPALKSSSKTKLPRISRTISFALRGLSSTPPRAQASTEVNVEHARGLPTSNSRKLSGVLADNRSVDSLSASDSASTVIDLAPSPETPQKPIKNTAITPSRPISIKVPPKQPLQDTEQQGRPAIPESVSTTTTEIALGDDTRLTAQPRRHGPKFEVNLSSGSRNGSSKSPQSKALAPWVRSVNPCNTPREVLRDTSWFGRWQHAYPRPPHVAVVKWKSLKSPAVLPLTTEEFPTPSELASDYLQTPYRVFPNEDSEGIEAPKTRGVLLREMISLRLSHGFQIVVGKNVVEASAQYTLQSPNVFDTHALERAGATVFLSKGNSIHRLICVEGAEIEVTRYTHRTSSLLASDQKRKFTLYSPAMRTILSPEYVVKDIKLDSTYEEYNWNYADNYVAGHRDYLFNPAQQLHFWRVRYVLIPMRLHFKSRRLHGFNEDNEEEIHLLGINQLTHIWQRHKYIPPEEKRFESSNKKRDQNPLNIMYQTRNPSEVIAAELDRIILVDPGLDSSPAQLLPESELLERSGISLSSLAQIIQGEKGVRMMDRRWHWRLHYNCFIGFELTTWLLQNFRDIDSREEAVEFGNELMKHGLFQHVEKRHNFRDGNYFYQISSEYRVSRPESRGSWFPQIRPDKSVPSTPVGEASKGSPISGHTRSDSTEDTQSQTPSTPSKLKNKASITLSKTMKYDVDPRKRSNRPEVIDLHYDRLHNPENCFHIELSWMNTTPKLIEDTVLSWASTAEKFGLKLVQVPIAEACAIDKTQPFRKPYCVQLKAPPPKGPIPLQCNSESFSQPVTLDHQYFHKALLRKFDFVLDFEARSSYPADVEVSYSWGMPDYQYPQYIHRSGSVLAQITGEGDFLLLANRLVSTRSAASRDMPRHERLDRPDQYRARAGTYDPVDRISPRLSPMARPVHEVHSPLSPQGHASIDSANLYRAPEHILTGFADFCNDPARLEQFYSEAQVRATSTKVGPAPTTLTDASIPSLELPASVVSHHISPPPGLPSRSSHNIAAPLSEIRRSRDDSNMSRGSPRSGSLRPLSLT
What are the official names of this protein?
Vacuolar membrane-associated protein iml1.
What is the protein family that this protein belongs to?
Belongs to the IML1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.