PharMolix/UniProtQA huggingface dataset:
Protein: EFG2_SHEDO
Sequence: MTELSKYRNIGIFAHVDAGKTTTTERILKLTGKIHKIGEVHDGESTTDFMVQEAERGITIQSAAVSCFWNDHRFNVIDTPGHVDFTVEVYRSLKVLDGGVGVFCGSGGVEPQSETNWRYANDSEVARIIFVNKLDRMGADFLRVVKQTKDVLAANPLVMVLPIGIEDEFCGVVDLLTRKAHIWDDSGLPENFEIKDVPADMVDLVEEYREMLIEAAVEQDDDLLESYMEGVEPSMEDIKRCIRKGTRTLTFFPTYCGSAFKNKGMQLLLDAVVDYLPAPDEVDPQPLTDEEGVENGEFAIVDADLPLKALAFKIMDDRFGALTFVRIYSGRLKKGDTILNSFTGKSERVGRMVEMYADDRIEIESAQAGDIIAIVGMKNVQTGHTLCDPKHPCTLEAMVFPEPVISIAVAPKDKGGSEKMGIAIGKMIAEDPSFRVETDEDSGETILKGMGELHLDIKVDILKRTYGVELIVGEPQVAYRETITAEVEDSYTHKKQSGGSGQFGKIDYKIRPGEANTGFVFKSSVVGGNVPKEFWPAVQKGFGSMMNTGTIAGFPVLDVEFELTDGAFHAVDSSAIAFEIAAKGAFRQSIAKAKPQLLEPIMKVDVFSPDDNVGDVIGDLNRRRGMIKDQNAGVTGVRIKADVPLSEMFGYIGTLRTMTSGRGQFSMEFAHYAACPNSVSEKVVTQVKERKAAEAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCAL_CLOBH
Sequence: MNVSAIVVEYNPMHNGHLYHIKKTKKLTNCDALVCIMSGNFVQRGFPSILDKWTKANMAISNGVDLVIELPTLYSLSSAEFFSFGAVSILDSLNIINSICFGSEIGNINALQDIATTLLEEPLEYKILLKNYLDKGISFAKARNLALVELNRDNKIMSENINKILSLSNNILGIEYLKSLLLLNSSIKPFTITREGADYKDENLHEEYSSASSIRKYLKENKNINILKDFLPLEGFLEFKRLITKGYNFSMEDSMINYIRYKYISGYKNLHNLIDVSEGLDNRIYKSLEKNFTYDSLVGEIKSKRYAYSRIGRILCQYFIGFENYDLNSLLKSTPNYMRVLASNEMGLKVLKKIKKHSSTNIYTKLPKNTNTLLSLDIKATNAYSLLNNNIRFNEDYFRSPTIIKNTIY
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRT14_VANPO
Sequence: MSSTGKATELQATMAVNSLLSNILPGANKMRKSNDNNNNKKNSKGTSKAQLIDRNLKRNLEIMDLDTHKFTKKNKIKKNKKIKKNVIKQNELKEIADLEIFKKHKIENNLTLSEKKKLNKIISKNLNKIKSRELDSDDQEELDDVQKFILDQTSNSQSYNKSKKRKTRRKEFKEFKNPDKNSSMDHRYPGLTPGLAPVGLSDEEDSSDEDDDRNDY
What is the function of this protein?
Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription 14.
What is the protein family that this protein belongs to?
Belongs to the RRT14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NADD_STRP3
Sequence: MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVADQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQGISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKAGTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RPOC1_STAPU
Sequence: MTYSNKPTGSSLRSSRNSTLEPQSLVHREESKRQEGPKGQNLRIGLASPEQIRNWAERILPNGEIVGRVLKPHTIHYQTHKPEKDGLFCERIFGPIKSGFCSCGKYKGTRDNDSPPFCEQCGVELTESRVRRHRMGYIQLSSPVTHVWYLKNRPSVISHLLEMPLKDVESLVYCGSFIIGPGTYSKFRLLGTLRIGTHERAYKRILTRKRLRTRKHFLQTKNISLASRSVTLEKSQEKVNDSLKLSQRIIIARKRLLRLAAKPILEPKLICNRFYVPWRIALELFLSKWYRDCESREIITGGYGIQRMLINLNLQNKLVSLQKNWERLVEQTEKMWFPVSGKYKNSDHSADIQREKRLIIRSSKIIRDLIQSKTQPEWMVLSVLPVLPPDLRPIVELREGQLITSDLNELYRKVLFRNEDLSIWLSYQGTLVLSGLLARLQRASLQRAVDALLANGMGSSTFRDYNKRAYKSFSALIKGKKGRFRENLLGKRVDYSGRSVIVVGPLLALHECGLPREMALELFQPFIIRELITRQLAPNLRAAKSMIQNKEPIIWKVLQVIVQNRLVLLNRAPTLHRLGIQAFQPVLVGERAILLHPLVCAGFNADFDGDQMAVHVPLSWEAQVEARILMWSPSNLLSPATGRAVAVPSQDMLLGLYVLTLEGSVGIYGSRQRSFVSSSLLFTKNHEIKESKEEDSQSKQDFIRSLDKKSKPIKNSKYSLYPKFIENKSSFHKFPIFYDYDDVIISIHQGHLNLFSFLWLRWEAKYPVISSRKGPIEYQFDSSGNSINIYDNSYIKKNRKGNSFSKYILTTAGRVLFNQQIQQSIQEHFSSLRK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PROA_PSE14
Sequence: MTESVLDYMTRLGRAAREASRVIGRASTAQKNRALQATAAALDEARAELSAANALDLANGQANGLEPAMLERLALTPARIDSMIVGLRQVAGLADPVGAIRDMSYRPSGIQVGKMRVPLGVVGIIYESRPNVTIDAASLCLKSGNATILRGGSEAIHSNRAIAACIERGLAEARLPAAVVQVVETTDRAAVGALITMPEYVDVIVPRGGKGLIERVSRDARVPVIKHLDGICHVYVSAHADLAKAQKIAFNAKTYRYGICGAMETLLVDQTIAADFLPAMAAQFREKGVELRGCERTRDLIDVIPATEDDWHTEYLAAILSIRVVSGLDEAIEHINHYGSHHSDAIVSDHQSQIRRFMAEVDSSSVMVNAPTSFADGFEYGLGAEIGISTDKLHARGPVGLEGLTCEKYIVIGDGQLRGQA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTMP_MOUSE
Sequence: MEEGSRSQSPREELELSMLDGPQEELTPLNNDLRIQPNSAEDPSPAQVGKESPWSPCNKSVVGKCKLWMVIVTIFLCFIIVIVISLCLVGVTYIDEDENEILELSSNKTFFITLKIPEECANEEGLHHLLTERLTDTYRQSPSLSRFFTSADILDFSVENATVTYHLQFGVPSEDDDFMKYMMSEELVLGIMRQSFHDKNISTCESLGLDPESLLLYE
What are the official names of this protein?
TPA-induced transmembrane protein homolog.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RL18_BACVZ
Sequence: MITKTSKNAARQKRHARVRAKLSGTAERPRLNVFRSNKHIYAQIIDDVNGVTLASASTLDKDLNVESTGDSAAAAKVGELVAKRASEKGVSDVVFDRGGYLYHGRVKALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SPC24_CANGA
Sequence: MASTEEIVQMMQEASAEFAEADDVSFLDKMNSNIAQLEQQLREQMDESRQNIAKLEINLIDTEKSIGSLRELMKDATDEATIMKGSDKLNNLIDELQATENEIQMMNSEIEKKVSKLVEDEDNTSSEYEMISKELEQEYDPVFASNILKLKLYRSLGVRLDLDNNQILIQNKELGTIDTLPLEDELTEFFKVKYIWSRIGK
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein SPC24.
What is the protein family that this protein belongs to?
Belongs to the SPC24 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: Y893_ENT38
Sequence: MPSFDIVSEVDIQEVRNAVDNASRELETRFDFRGVEATFELNDANKTIKVLSESDFQVNQLLDILRAKLLKRGIEGASLDVPEEFVHSGKTWFVEAKLKQGIESAMQKKIVKLIKDSKLKVQSQIQGEEIRVTGKSRDDLQGAMALVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein Ent638_0893.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: KC1_PLAF7
Sequence: MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILGGGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIEYVHSKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGLAKKYRDSRSHTHIPYKEGKNLTGTARYASINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKISTSVEVLCRNASFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDLFIREGFTYDFLFDWTCVYASEKDKKKMLENKNRFDQTADQEGRDQRNN
What is the function of this protein?
Serine/threonine-protein kinase likely to be involved in many cellular processes (PubMed:26629826).  Phosphorylates rhoptry protein RON3, nucleosome assembly protein NAPL and DNA/RNA-binding protein ALBA4 in vitro (PubMed:26629826).
What are the official names of this protein?
Casein kinase I, Casein kinase 1, PfCK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Protein: PNO1_DICDI
Sequence: MTEVIETKEVENIISEQSLKTESVKVSNKRSRDDEEMKDSEGGVKKTSFPQISVEDTEEEQIRKVTIPFNRIAPLKANWQQIYEPIVTHLKLQIRMNTKTRKVELKTSKSTKETSALQKAADFVHAFSLGFEVNDAVAILRLDDLYIDSFDVEDVKILKGDNLSRAIGRVAGKDGKTKFTIENVTKTRIVLADKRIHILGSYSNIRVAKDAICDLIIGSPPGKVYAKLRTVSSRIAERF
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
What are the official names of this protein?
RNA-binding protein pno1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ASSY_ARCFU
Sequence: MKVVLSYSGGLDTTVCIPLLKEKYGFDEVITVTVDIGQPEADIKQAEERGKKYADKHYTIDAKKEFVDSLFMLIKANGNYEGYVLGTALARPLIAEKVVEVAKKEGAEAVAHGCTGKGNDQLRFENIFRQHGFKVIAPVRELNLTREWEIEYARQHGIEVPATKEKPYSIDENLWSRSVEGGKLEDPSFEPPEDIYEWTASPEKAPDKPEIVKIDFEKGVPVALNDERMGGFELIKALNEIGGKHGVGRTDMIEDRVLGLKARENYEHPAATILITAHRDLENLVLSRRELKFKKFVEEEWAELVYYGLVNDPLFDALNAFIDKTQERVTGWVKVKLYKGSAVVVARNSPYALYSEELVSFDTESIDQRLAEGFAAFHGLQGRLFRRLFQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_ACIBY
Sequence: MAIRRIEGLLHLASEGRYAILVGRFNSFVVEHLLEGAIDTLKRHGVNEDNITVIHAPGAWELPIVAKKLATSNQFDAIIALGAVIRGSTPHFDFVAGECAKGLGVVALESSLPVINGVLTTDSIEQAIERSGTKAGNKGSEAALTAIEMVNLLKAI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SSK2_YEAST
Sequence: MSHSDYFNYKPYGDSTEKPSSSKMRQSSSSSSSRLRSESLGRNSNTTQARVASSPISPGLHSTQYFRSPNAVYSPGESPLNTVQLFNRLPGIPQGQFFHQNAISGSSSSSARSSRRPSNIGLPLPKNPQQSLPKLSTQPVPVHKKVEASKTESEIIKKPAPVNSNQDPLLTTPTLVISPELASLNTTNTSIMSTPQNITNQTSNKHIPTRSQPNGSTSSSTLQDIVTTNSSQRSVGHHGGSTTSLRTYKKQYVLNEQLYLRKMRNRANDDYYTRGIVASSNFEDDEENFSNKGEDDLELEMDDLLKVEGEDKDNDFNFGYNFITSSTKNNENVVSMSLNYLKGKLDWLRDVNNDQPCEIEDEEWHSILGSEDLLSKLLQNPMVNNRFEWQTMLSKVLKGDIVRNEKTKIANQGKGPGFNTQFSDDIWIELKAWMNGRTVEDQNKSLRIFRDSTDSVFQEIMAFKLEDNMSADEAAETIKSLVDKYYRVLNLWPNIKRMHAEKPITKTEAFRNRIDTLNSWLNFKFNFDTNIAYLKKWIVGNKELESTTEVDNTTVNLDDPAVFATNCKRFAEQIMKEKDIELIFQKKIFFPLAPWILKAKFFFLKYQKTWNELNLSYLDQDLEFLLMFPMRLVKDIILIRLSYAKKIQNPTLMMIDQMMDDFSTYIKLAVQMKFTVASYCNDWFFKVKIDPEFDHTVVEGLEYFFSILELRILYSGKNSFKTSKEPDLLLKYWEMFRNVGYYIDDAGELIAAEFTKLTLRLVHRLHAYLLRQQNTPPKLENEAAAEKWLVQIFEILGSMKRKLNRFTNILTKAFQNFVRYKIEDHNYLLKQLKETGHFLIYTGGYLEQNGTYLIGSPELLGCKDDDILRIIKNSDIGCDLVPKLEINNSLTIYNALDDNWNSNSSLGSDISNDGTPFYYIKNDLTTQPRSYNGNRVNREPDFENSRSTEEEFYELETRLNSLGYVLVLTPQEPLLWEGEMYNLSDNKTIKPEGLNLKVIPNSIDLMCQGSSYALEYQCDRFQQISGSSVSFLEKKSSSETVKNNLQRINKAYFRCTYSVLKNYTKIVTTFKKVSPVNDLLNNIFLFGRDFGLNFLRINVANNEKRSIIILLMMRLSIGWLKFLAEDCDPTDQRVFRWCVTSMEFAMHMVSGWNILALDECQFSSLKQKISECMSLLISHFDIIGARSIEVEKINQQARSNLDLEDVFDDDMMLQVNSEFRVQSIMELEERIKRNPHQTGKVIDDSDKGNKYLVSLASSISNVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPWIVQIREIAFGDDSSSTDTEERE
What is the function of this protein?
Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Activates the PBS2 MAP kinase kinase by phosphorylation.
What are the official names of this protein?
MAP kinase kinase kinase SSK2, Suppressor of sensor kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: BSHC_STAAE
Sequence: MDCKVVSLNEKDQFIPKIKSSDPVITGLFQYDAAQQTSFEKRMSKENNGREAALANVIREYMSDLKLSSEQELNIQHLANGSKVVIGGQQAGLFGGPLYTFHKIFSIITLSKELTDTHKQQVVPVFWIAGEDHDFDEVNHTFVYNENHGSLHKVKYHTMEMPETTVSRYYPDKAELKQTLKTMFIHMKETVHTQGLLEICDRIIDQYDSWTDMFKALLHETFKAYGVLFIDAQFEPLRKMEAPMFKKILKKHQLLDDAFRATQQRTQNQGLNAMIQTDTNVHLFLHDENMRQLVSYDGKHFKLNKTDKTYIKEEIINIAENQPELFSNNVVTRPLMEEWLFNTVAFVGGPSEIKYWAELKDVFELFDVEMPIVMPRLRITYLNDRIEKLLSKYNIPLEKVLVDGVEGERSKFIREQASHQFIEKVEGMIEQQRRLNKDLLDEVAGNQNNINLVNKNNEIHIQQYDYLLKRYLLNIERENDISMKQFREIQETLHPMGGLQERIWNPLQILNDFGTDVFKPSTYPPLSYTFDHIIIKP
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: KCMB4_HUMAN
Sequence: MAKLRVAYEYTEAEDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCGADCRGTSQYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCKRENQKNLESVMNWQQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTICAKSLAVKAEAMKKRKFS
What is the function of this protein?
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel.  Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.  Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics.  May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations.  Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.
What are the official names of this protein?
Calcium-activated potassium channel subunit beta-4, BK channel subunit beta-4, BKbeta4, Hbeta4, Calcium-activated potassium channel, subfamily M subunit beta-4, Charybdotoxin receptor subunit beta-4, K(VCA)beta-4, Maxi K channel subunit beta-4, Slo-beta-4.
What is the protein family that this protein belongs to?
Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB4 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNAA_PSEPK
Sequence: MSVELWQQCVELLRDELPAQQFNTWIRPLQVEAEGDELRVYAPNRFVLDWVNEKYLGRLLELLGENGSGIAPALSLLIGSRRSSAPRAAPNAPVSAAVAASLAQTQAHKTAPAAAVEPVAVAAAEPVLVETSSRDSFDAMAEPAAAPPSGGGRAEQRTVQVEGALKHTSYLNRTFTFDTFVEGKSNQLARAAAWQVADNPKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSERFVADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLTVAVEPPELETRVAILMKKADQAKVELPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRDITIELIRESLKDLLALQDKLVSVDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGDMFGGRDHTTVLHACRKINELKESDADIREDYKNLLRTLTT
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_STRSV
Sequence: MKKIVFTGGGTVGHVTLNLLLIPKFIKEGWQVHYVGDKHGIEYQEIQKSGLDVTFHSVATGKLRRYFSWQNLLDGFKVVWGIFQSLGIMLKVRPQALFSKGGFVSVPPVIAARLSGVPVYVHESDLSIGLANKIAYKCATKMYATFEQPSSLNKIEHVGAVTKVGSQESVLPQELEEIRQYFDKELPTLLFVGGSAGAKVFNDFVSQNQAALTERYNVINLTGDASLDVLSERLFRRAYVTDLYQPLMDLADVVVTRGGSNTIFELLAMAKLHIIVPLGREASRGDQIENADYFVKKGYAKQLAEEQLDMSHLQAALDDLLANQASYHQAMKNSQEIKSVDEFYALLKADIDKGKK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: STR18_ARATH
Sequence: MSQSISSSTKAEEVVSVDVSQAKTLLQSGHQYLDVRTQDEFRRGHCEAAKIVNIPYMLNTPQGRVKNQEFLEQVSSLLNPADDILVGCQSGARSLKATTELVAAGYKKVRNVGGGYLAWVDHSFPINTEEEEPSAN
What is the function of this protein?
Catalyzes the transfer of a sulfur ion from a donor to cyanide or to other thiol compounds.  Substrate preference is thiosulfate > 3-mercaptopyruvate.
What are the official names of this protein?
Thiosulfate sulfurtransferase 18, Sulfurtransferase 18, AtStr18.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_IRISE
Sequence: MEELQGYLEKDRSRQQPFLYPLLFQEYIYALAHNHNRGLKGSLFYEPTEVFGYDSKSSLALAKRLIIRIYQQNDFLSVVNDSNKNRFVSHHRYNFCYSHFYSQMISEGFAILVEIPFSLRLVSYFEKKEIPKSHNLRSIHSIFPFLEDKLLHLNYVSDIRIPHPIHMEILVQILQCWIQDVPLLHFLRFFLHKYHNWNWNSFLITPKKSIYVFSKENKRLFRFLYNSYVSECEFLLVFLRKQSSYLRLTSFGLFLERRHFYVKIKRLQMQHLILIVVCRDYFQKALXXXXXXXXXXXRCQGKVVLAPKGTHLLMKKCKYNFVTLWQYYFHFWYQSYRIHINQLSNYSFYFLGYLSSLLKNSSTVRNQMLENSFLVDTVTNKLETLVPVIFLIGSLSKAQFCTVSGHPISKPIWADLPDSEIIERFGRMCRNLSHYHSGSSKKQGLYRIKYILRLSCARTLARKHKSTVRAFLRRLGSGLLEEFFTEEEQVLSLILPKTIPFTFYGSHKERIWYLDIIRINDLVNHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOY_STRR6
Sequence: MIYKVFYQETKERSPRRETTRTLYLDIDASSELEGRITARQLVEENRPEYNIEYIELLSDKLLDYEKETGAFEITEF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: UXUA_LACLM
Sequence: MEMTMRWFGSNADKVELSEIAQVPGVKGVVGMIMDIPAGEVWPKERIKALKEEIEAAGLSLKVIESVNIHDDIKIGLPTRDKYIENYKETIRNLAEFGIEVICYNFMPVFDWLKSDLDYRLADNSQTMAFVAEDIPENPQEIIDRVQAADGGFSLPGWEPERLSEVKDLFEAYKNVDEHKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYPMFGLPRVVKNREDLDWICNVVDSPSNAITLCTGSIAEDPANNVYEIMAEFVKRDRIPFAHVRNIKFLPSGEKDFYEAPHMSEYGSLDMYKILKAMYDNGFDGYIRPDHGRMIWGETGRPGYGLYDRALGASYLNGLWEALEKNKQ
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: G6PI_ACIVR
Sequence: MNYKQPLIVKSQQQALSALRNLKMQTQDTHLNQFFSDDSGRFERFSVEQEQLVLDFSKHRIDQNVLNGLVDLAHAQDLTQWIQRLFSLEEINYTEQRAAMHWALRVPEQNQQVLPEITAQVHTQLERMYSLVEKIHAGQYRGATGEVIQDVVNIGVGGSDLGPLMVTHALSDFKVVTAKPLDVHFVSTMDGSQLSDLLHQLRPETTLFIISSKSFGTIDTLSNAQTVRQWLEKALGKNSHVLKHHFIGVSTKPDKMSEWGIAPENQLLLWDWVGGRYSLWSCIGLPIALTVGVDGFKQLLSGAYAIDQHFQTAPFAQNIPVLIGLLGVWNNNFLDIQTHAVLPYDGRLKYFAAYLQQLEMESNGKSTQRSGEKVDSATCPIVWGEVGPNAQHAFYQLLHQGTHKVSCDFIAPVKRYNANHFTYAENAEALIEQHHLALSNCLAQSRLLAFGNQALTADEIEDLPTYKQYEGNQPSSTILLKELNPYSLGMLIATYEHKVFVQSVLWNINPFDQWGVEKGKEIANQLLPILNREQDDLSTFDASTQGLLKILLGKNNG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSPF_CERCE
Sequence: VIGGDEXDINEHRSLALMYXSWSHRFIXXGXLI
What is the function of this protein?
Thrombin-like snake venom serine protease that displays clotting activity on fibrinogen.  Shows both arginine-ester hydrolase and amidase activities on synthetic substrates.  Also shows proteolytic activity toward casein.
What are the official names of this protein?
Thrombin-like enzyme RP34, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP, Venombin A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EGFLA_MOUSE
Sequence: MDLISTFSLHFLLLACSLPPGAVSLRTALRKSGKVGPPLDIKLGALNCTAFSIQWKTPKRSGSSIIGYTVFYSEVGSDKSLRERSHNVPVGQDTLITEEVIGDLKPGTEYQVSVAAYSQTGKGRLSFPRHVTTLSQDSCLPPAAPQQPHVLVVSDSEVALSWRPGENEGSAPIQSYSVEFIRPDFDKSWTIIQERLQMDSMVIKGLDPDTNYQFAVKAMNAHGFSPRSWPSNTVRTLGPGEAGSGHYGPGYITNPGVSEDDDGSEDELDLDVSFEEVKPLPATKVGNKKFSVESKKTSVSNSVMGSRLAQPTSASLHETTVAIPPTPAQRKGKNSVAMMSRLFDMSCDETLCSADSFCVNDYAWGGSRCHCNLGKGGEACSEDIFIQYPQFFGHSYVTFEPLKNSYQAFQVTLEFRAEAEDGLLLYCGESEHGRGDFMSLALIRRSLHFRFNCGTGIAIIISETKIKLGAWHTVTLYRDGLNGMLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLSVNGKKIDMRPWPLGKALNGADVGECSSGICDEASCIHGGTCAAIKADSYICLCPLGFRGRHCEDAFALTIPQFRESLRSYAATPWPLEPQHYLSFTEFEITFRPDSGDGVLLYSYDTGSKDFLSINMAAGHVEFRFDCGSGTGVLRSEAPLTLGQWHDLRVSRTAKNGILQVDKQKVVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGILHPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVGAPCAHGGSCRPRKEGYECDCPLGFEGLNCQKECGNHCLNTIIEAIEIPQFIGRSYLTYDNPNILKRVSGSRSNAFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALIFSYNLGSGVASIMVNGSFSDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGLMRQLNINGALYVGGMKEIALHTNRQYLRGLVGCISHFTLSTDYHISLVEDAVDGKNINTCGAK
What is the function of this protein?
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception.  Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse.  Promotes matrix assembly and cell adhesiveness.
What are the official names of this protein?
Pikachurin, EGF-like, fibronectin type-III and laminin G-like domain-containing protein, Nectican.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Synaptic cleft. Presynaptic active zone. Note=Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells (PubMed:18641643). Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals (PubMed:18641643).