PharMolix/UniProtQA huggingface dataset:
Protein: AN13C_MOUSE
Sequence: MTGEKIRSLRRDHKPSKEDGDVLEPCEEEATAALGGAFTGGRSGPGGSGKGGKACHKIFSHHHRLQLKAPAVPGPGVPAPPQHNAVTATCPAPACLGGSNPALVADGGGCPSLYPVHECVFKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVGEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGSLAEQSFEPVRRQSLTPPPQNTITWEEYISAENGKAPHLGRELVCKESKKTFKATVAMSQEFPLGIESLLNVLEVIAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRCDEFDGSIFAIPEDYKEDPSRFPDL
What is the function of this protein?
Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 13C.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Note=Associated with the cytosolic side.
Protein: MANA2_ASPTN
Sequence: MKVPRLLLALGGLASIHIASALPQGAVERDMHATSAVVHGGNVKTKFPSTTGLKFTIDGETGYFAGSNSYWIGFLTNNADVDLVFQHMKESGLKILRVWGFNDVNTKPATGTVWYQLHANGTSTINTGPDGLQRLDYVVHSAERHGIKLIINFVNNWNDYGGINSYLQAYGGASNEDFYNSEPMQKAYRAYIKEVVSRYIDSPAVFAWELANEPRCKGCDTSVLHSWIEKTSRYIKSLDKKHMVTTGEEGFGLDLMSDGSYPFTYVEGGNFTDTLSIPTIDFGTFHLYPSSWGTTNDWGNLWVEAHGAACKAAGKPRLFEEYGVTADHCALEKPWQTTALKTKGVSGDLYWQYGDTLSTGPSPDDGNTFYYGTDEFDCLVSDHVAAIDEMEKHGRH
What is the function of this protein?
Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.
What are the official names of this protein?
Probable mannan endo-1,4-beta-mannosidase A-2, Endo-beta-1,4-mannanase A-2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FREM3_MOUSE
Sequence: MAGDSLSLPGMSLQLLVTLTCLLLTCALRERVPLSENVSHCELYLPPWGALNGGSHQNPGILIANSGFQVPQGRSVWLNPLRDLVIRVQRGDQCKVTVLDFPRLQGALSPHQFPCDFGAQQVKYTHFGSPSSTRTRIQLQVRYDAGNSTLVLPFTLQVNVVFPKLQLVARNRPLKVFKVLGCSHAIDRRVLNFASRSRCRLTVLPHPGGPLPKYGLLVDTAGNPLSRGHLADCEAFIQAGVRYQHTTTPSSPSRDYVPMLVELLGPESQGTRSVEVLAQEYFQIQVRIQKRARSTAPIPSLAALMIVEVEQSLLTALTPDVLAAEDSESDPDDLVFNILNVPEAPPGHHGGQGYVVNTDDPLGLPVSFFTQKELRELKIAYRPPTGSSEGDHVFQLKLQVVDEDGDTSEPFAFMVVVKSMNVLAPIASYRGGLVVFEGQARPLSDALSFQVSDKDNSKEIKIVAVRGLQHGQLVVHGAPAGCKNFTLADLSAGRVVYQHDGSDSYSDNIILKMEGEHHRVDFLFPITIVPVDDAAPVLTANMGLSVTEGQVVQISPFVLCATDIDSEDSAILFVLEDEHLEGKEEETHEDLAPGSYSSSQHPGNMLLRQAEPPSSLLYSDWHYVEKEGLYETVVTEWLQRDIMEGRLFFSHPGPHSPSPVAHLAFHVQDDQDPPNLSNQHFFTISIQPADTSQPQLSPETTLEMTVQGYQLTPFQQKYLQYTDQNSDEQNLWYTLLTRPTDADSNHQVQAGEIVLTDSPGRPIVHFTQTQVNHQKIAYRPPQRNLGIVPRVVQFTYKVEDTAGNSVSGTFTVFLQPLNNQPPKVINRGFAVLEGDSFILGRGELNVSDPDTNDDQIFFILVWGPQHGHLQYFKKYMVPGESFMLADVINGSISYQNSRDQTDSDVIYLEVSDGVHHIPITVQVSVQPTVADRSPGISITGTPVLATSLTVLENAASEITMDVTHGRKNTNDLMLSFIVEDKPKLGMILVNGWPAEQVTQEDLLGGAVSYVHTSGEIGFQRVHDTFSFILSKDAYHRAMRDNILERVLVEVTVLPVDNMAPKVLVRKPFIVYEGGKNLLTPQHVNIEDVDTSKDEILCTLTVQPSSGYLENLAPAPGSEVSRAGNPISAFFVKDVRVGCINYVQSIHKGIEPGADQFTFYCSDGINFSPKVLLPLTILPTNDEQPQLFTREFVVLEGMSRVIDTSLVNGVDADFPSDKHFRLTVFPQHGQITQQLATGSKPIHSFTLQEIQEPSSIAYEHDDSESTEDSFEVWLSDGRHTTHTTVPIAVILVDDEVPQLTINDGLEIETGHSEIITNHILKAIDLDSDNKSLSFVLHSEPQQGLLQRLRKPGGDAKHNLTVGMNFTQDEIDRGLIHYIHTGQGEAVDLKFDVTDGVNTLRDRYFYITIDNSNSAVPEIVSKRVTLTEGNRMTLTTELLNTSDIHSPGEQLLYSITRAPSTGHLESSDQPGEPMASFTQLQLARNKISYVHISNDKIKLDHFELRVTGGHHSESRIFRIFVTEQDNKKPTLTIQALALQRGDNIVVTPSQLTVEDEDTPADFILFTITQIPIHGRILYNGSRPVTTFTKKDLTKSLIYCHDGSETSKDSFSFTVTDGIHTGFYVFPDTSLETHVPQTVWIQISPFDDRLPQMGINRGATALKLLHTGHLGFLITNEYLQATHQGVPHRLLTYKVTRGPEHGYIVNAGLGNENTHMFTQADIDEMRVYYILNKGRGRATRDTFYFSVETRGGKQLRNQPFHLNWAWISLEKEYYIVDEDSPFFEVTLRRGYLGGTSVVSIGTKGDTAEENKDFKGKAPMLVQFSPGQSTATWRVGLIPDTKYETSETFQIILSEPGAAALEFPEMATVEIVDPEDESTVYIPEAEYQLAEAVGEFLVPVRRSGDTSQELTVICSTRPGSATGTIPSVQLSLSDYVSRPEDNTSMLHFEKDESEKTCQVLIINDSLYEEEESFSIALSLPTGGQLGAKFPTARVTILADREDEPALHFECSEYHAEESAGYVEVAVWRRGTGLSQASSVIVRSRGTEEQAAEAGTDYIGVRQHLHFSPGVSVQRLRVTILDDLPQPAFEGPEMFELLLQMPTGAVIGEPNKTTVTINDSVTNCEECV
What is the function of this protein?
Extracellular matrix protein which may play a role in cell adhesion.
What are the official names of this protein?
FRAS1-related extracellular matrix protein 3, NV domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the FRAS1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RPOZ_SALSV
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: EX7L_NATTJ
Sequence: MSERTVTVSQLTNYLKNLLLQDHNLKNVLVRGEISNFKHHSSGHMYFTLKDEGASLRCVMFRNRNWNLDFSPQDGMDVIVQGVVGIFERAGLYQLYVEKMYSHGLGSLHLAFEQLKEKLAEEGIFNEEYKKTLPPFPKKIAVVTSPTGAAVRDMIVTISRRFPLTSILLIPVRVQGEYAASEIRAGIDYANSIDDIDVILVGRGGGSLEEIWPFNTEEVARAIFSSKAPVISCVGHETDFTISDFVSDLRAPTPTAAAELVVPDQVELKRQVSDYKHRLTKALYHKYRNLDQRVVELLDRPVMKNPYTLISERKKELEYLDQRLLREVYHLFKLKRNKYSSLVEQLDSLSPLKTLGRGYTFCQTHDGDIVRSVTDIEQEDILKLTFFDGSAKCLVKEKQEHHISEDHSNLNSLCNEEEDYDRQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACIN1_ARATH
Sequence: MAMKTSHVLLLCLMFVIGFVEARRSDTGPDISTPPSGSCGASIAEFNSSQILAKRAPPCRRPRLQNSEDVTHTTLP
What is the function of this protein?
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation (By similarity).  Inhibits the fungal growth of Alternaria brassicicola, Sclerotinia sclerotiorum, Fusarium graminearum, yeast (Saccharomyces) and Botrytis cinerea, thus being an antimicrobial peptide (AMP) (PubMed:25593351).  Promotes resistance to A. brassicicola and B. cinerea (PubMed:25593351).
What are the official names of this protein?
Peptide ARACIN 1, Phytocytokine ARACIN1, Mature form of ARACIN1, mARACIN1, Precursor of Peptide ARACIN 1.
What is the protein family that this protein belongs to?
Belongs to the serine rich endogenous peptide (SCOOP) phytocytokine family.
Protein: ZAPD_YERPS
Sequence: MSDLTSTILFEHPLNEKMRTWLRMEFLLQQLESHRSLDNIANALTFFRTASDLIDVLERGEVRTDLLKELERQQQKLQQWADIPGVDVSLVDSLRNQLKSRAAVLMSAPRIGQSLKEDRLISVVRQRLSIPGGCCSFDLPTLHVWLHQPSEQRDQHINKLLASLAPLHQSLTIILDLIRQSCPLRSQISLNGFFQDNAGGADLLRLRLPLDPQLYPQISGHKTRYAIRFLALDSENGTVPARLSFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: MS116_ASPOR
Sequence: MKTGRTRPLRVFDILVPPWPPTVPHRIKLPRGKTNWFEFYSAITRNWNKLKGLKNCWQIWKDVQEIIRRIRKYQGESTVMQGPGNNDGAHPYATMAGKLDSKLLQALKVMEFEYMTPVQHRVLTELPSWRSDCLVQAKTGTGKTLAFLLPTLHCLLQGHSAPPRGQVAILIITPTRELAQQIAKSCDQLTSQLARPLECHIAVGGTARASALARFMKGAPSILVATPGRLKDYLSEPSTAEKLSNIQTLILDEADTMLESGFLADVKRILQLIPPKSTGWQGMCFSATVPPKVKDVVSVVLKPGYTSISTIEKNETPTHERVPQYHVLIPSVADTFTTLASLLNLEIKNSSKIIVFGVTANMVALFAAAFSQGLTPLKVFEIHSRLSQSARTKTTALFKEAATGIMFASDVIGRGMDFPNVDLVIQVGLPSNGEQYVHRVGRTARAGNDGRAIILLTEAESFFMKVNRHLPIQPHPQTDAINAGASSCADAVTKAMYSIGEETKQRAYSSYIGFFAGSGLLKQVRLDKPGLVQLANELAIQGMGCPEPPPMDKKVVGKMGLKGVPGFNYATGNDLNGDRPARPRGRPGNKTRDVLSPGAGQGDRRGSVSKNRGGRRGGGRGGRGGRGGKPRAA
What is the function of this protein?
ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns.  Also required for efficient mitochondrial translation (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase mss116, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: HSLV_SHIF8
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDICIYTNHFHTIEELSYKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV, Heat shock protein HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPC3_BOVIN
Sequence: MAAPEQPLPMSRGCQNSSSLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRDLSDKGRLKHTAFATFPNEKTAVKALTRLHQLKLLGHTLVVEFAKEQDRVHSPCPSLGTEKKKRSDDPVEDDKEKKELDCLTIENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITTRPPMYEDYMPLHAPLPPTSPQPPEEPPLPDEDEELSSKESEYESSDDEDRQRMTKLMELANLQPKRPKPIKQRHVRKKRKIKDMLNIPSSASHSLHPVLLPSDVFDQPQPVGNKKIEFHISTDMQVAFKKDLEKQQNCEEENSDLPATEADASNIGFGKIFPQPNLNITEEIKDDSDEMPSECISRRELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLAKHVQEKDLKFIFGRYVDFSSETQRIMFDIRLMKEGRMKGQAFIGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDSKEGKRKC
What is the function of this protein?
Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns.  U12-type introns comprises less than 1% of all non-coding sequences.  Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA (By similarity).
What are the official names of this protein?
RNA-binding region-containing protein 3, RNA-binding motif protein 40, RNA-binding protein 40.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL14_SINFN
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRKYASIGDIIVVSIKEAIPRGRVKKGDVMKAVVVRTAKDIRRPDGSVIRFDTNAAVLIDNKKEPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: AMTAB_METJA
Sequence: MWLYYLQVVMDMRVYVEGYGCVLNTADTEIIKNSLKKHGFEVVNNLEEADIAIINTCVVRLETENRMIYRINELKNLGKEVVVAGCLPKALKNKVKGFLHIYPREAHKAGEILKNYVEKHYRMPYIEEDINKTLYKKLDYLKPSLITPLPICEGCIGNCSYCIVKIARGGLISYPREKIVNKAKELINKGAKCLLITAQDTACYGFDIGDNLANLLNELTQIKGEFIMRVGMMHAKNAELILDELIEVYQNEKVGKFLHLPLQSGDDEILKRMKRGYTVDEFKDIVNEFRRKIKNLCFTTDIIVGFPGETEEQFQNTLEVLRELKPDYIHGAKYSQRKGTEAAKMKQIDTKIRKRRSEILDKLRRELSYLNNKKYIGKAMKVLVLDEGKGYTDNFKVVKFEGGEVGEFRKVKITDAKTFGLKGELIL
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Probable threonylcarbamoyladenosine tRNA methylthiotransferase, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
Protein: MARC_SHIF8
Sequence: MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAPPLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTYH
What are the official names of this protein?
UPF0056 inner membrane protein MarC.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CPXP_SHIFL
Sequence: MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSHMFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKMANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSSSNSRSQ
What is the function of this protein?
Acts as an accessory protein in the Cpx two-component envelope stress response system.  Binds the periplasmic domain of sensor histidine kinase CpxA, inhibiting induction of the envelope stress response in the absence of inducer.  Aids in combating extracytoplasmic protein-mediated toxicity.
What are the official names of this protein?
Periplasmic protein CpxP.
What is the protein family that this protein belongs to?
Belongs to the CpxP/Spy family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RRP3_EUGGA
Sequence: MKKELILKFLWLEKSIAVCLDQKVGDSITPLTEFFFWPQKDAWEEMKNFLESQSWITQSDSVNLLNNITEVINFWQERDTNVIDRKHISNLREKFPDIIVIGQ
What is the function of this protein?
Probably a ribosomal protein or a ribosome-associated protein.
What are the official names of this protein?
Probable 30S ribosomal protein 3, chloroplastic, PSRP-3.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cS23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2504_CLOBB
Sequence: MIITTTPSIEGKNILEYKGVVFGEVISGVNFIKDFAAGLSNFFGGRSNTYEGELIEAREKAMKEMENRAIQIGANAVVGVDIDYEVLGADNGMLMVTASGTAVYYE
What are the official names of this protein?
UPF0145 protein CLL_A2504.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PANB2_METPP
Sequence: MSSHSSPADTPSARKPVTLHTLREMHARGEKIAMITAYDASFAALVDTAGVDCILVGDSLGMVLKGQSSTLSVTMEQIGYHTRSTSRGTKAAFLIADMPFGSYQENPVQALRNAGTLMAAGAQMVKLEGGGWTPETVNFLVERGVPVCAHLGLTPQSVHALGGYRIQGKDEAGAATLRRHAKALADAGAAMMVLELMPSRVAREVQADNPGLMTIGIGAGAGTAGQVLVLHDMLGVTRGRLPRFVRNFMDSATSIEDAVRRYVAAVKDGSFPDETLHAY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase 2, Ketopantoate hydroxymethyltransferase 2, KPHMT 2.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_UREP2
Sequence: MTRKDFFNVLTRYFPWVDEQTFMSFEKYKTIIQKYNQIFNLTRLDSDDKIYQNFFLDSLAPYKELDFFTQNTNLKLIDIGSGSGIPGVVLKIIFKNLNLTLLEANQKRCEFLKILTQELGLNDVLIWNMRAEDLTQSMRESFDIATSRAVASLDKILEISAAFVKVNGYLIQPKSIKFYEEELKAKNIIKTLYLERIALKDFWENDYHHLVGVYLKKQITPLQFPRPWNLILKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCAT1_HUMAN
Sequence: MRLRGCGPRAAPASSAGASDARLLAPPGRNPFVHELRLSALQKAQVALMTLTLFPVRLLVAAAMMLLAWPLALVASLGSAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGRQALPTEAAILTLAPHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAEALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAFKMYGAQEDGSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYPDQTHFESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD
What is the function of this protein?
Exhibits acyltransferase activity (PubMed:21498505, PubMed:18156367).  Exhibits acetyltransferase activity (By similarity).  Activity is calcium-independent (By similarity).  Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (PubMed:21498505, PubMed:18156367).  Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity).  Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively (By similarity).  Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) (By similarity).  May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology (By similarity).  Involved in the regulation of lipid droplet number and size (PubMed:25491198).
What are the official names of this protein?
Lysophosphatidylcholine acyltransferase 1, LPC acyltransferase 1, LPCAT-1, LysoPC acyltransferase 1, 1-acylglycerol-3-phosphate O-acyltransferase, 1-acylglycerophosphocholine O-acyltransferase, 1-alkenylglycerophosphocholine O-acyltransferase, 1-alkylglycerophosphocholine O-acetyltransferase, Acetyl-CoA:lyso-platelet-activating factor acetyltransferase, Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, LysoPAFAT, Acyltransferase-like 2, Phosphonoformate immuno-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Protein: RNAS2_GORGO
Sequence: MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMRVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
What is the function of this protein?
This is a non-secretory ribonuclease.  It is a pyrimidine specific nuclease with a slight preference for U.  Cytotoxin and helminthotoxin.  Possesses a wide variety of biological activities.
What are the official names of this protein?
Non-secretory ribonuclease, Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, RNase 2, Ribonuclease US.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Protein: MCE_RDVA
Sequence: MSNPDYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMSSGTHVHIIDGSVEITASLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQVMKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYGPTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFIAKYFNEEAVPIDKRIVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVINELVLKSKVKYVMHNPQIKLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTDAMAKATGAKVIGVNKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYEKFQAEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGASIREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMITTVGDALKMDLDGGRAVIASYSLSNSSNPKERVLKFLSDANKAKAMVVFGAPNTHRLAYAKKVGLVLDSAIKMSKDLITFSNPTGRRWRDYGYSQSELYDAGYVEITIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSPAALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSGSKTFTVLNHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILWAEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICESYAAMMLNNKHSPDIIGTLKSAINLVFKI
What is the function of this protein?
Enzyme involved in mRNA capping (Potential).  Binds to GTP and might have guanylyltransferase activity.  Together with the RNA-directed RNA polymerase P1 and protein P7, forms an transcriptional complex positioned near the channels situated at each of the five-fold vertices of the core (By similarity).
What are the official names of this protein?
Putative mRNA-capping enzyme P5, Structural protein 5, mRNA guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus protein P5 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Located inside the inner capsid. Found in the interior of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: HIS7_GEODF
Sequence: MSRKAVVERITKETQIKLSLDIDGAGEAKVCTSVPFLDHMLNLFARHGLFNLEVEAKGDIDIDFHHTVEDIGIVLGEALKQALGDKSGIRRYGQASVPMDETLASVAVDLSGRPYLAYNVRLPKVKIGDFDVELAREFFQALTNNLAANIHINVMYGDNVHHILEACFKALARALDQATQHDPRISGVMSTKGKL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIM1_YEAST
Sequence: MGKAAKKKYSGATSSKQVSAEKHLSSVFKFNTDLGQHILKNPLVAQGIVDKAQIRPSDVVLEVGPGTGNLTVRILEQAKNVVAVEMDPRMAAELTKRVRGTPVEKKLEIMLGDFMKTELPYFDICISNTPYQISSPLVFKLINQPRPPRVSILMFQREFALRLLARPGDSLYCRLSANVQMWANVTHIMKVGKNNFRPPPQVESSVVRLEIKNPRPQVDYNEWDGLLRIVFVRKNRTISAGFKSTTVMDILEKNYKTFLAMNNEMVDDTKGSMHDVVKEKIDTVLKETDLGDKRAGKCDQNDFLRLLYAFHQVGIHFS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.
What are the official names of this protein?
Dimethyladenosine transferase, 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, 18S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: DCUP_PICTO
Sequence: MNSFISMIRNGYSDTIPVWFMRQAGRYLKEYNEKKGRMTIKEICMDPELIAGISYDPVRILNVDAAIIFSDITIPLEALGYKIEFLPGGPRIINGYIKNHDMKDIIYFEESNFKYKIYDAIKIFKEKYHFPLIGFSGGLITVLSYIIAGGPDSNLNLTKRSMLSDDKFNDYINIIKDMIIKYIRLQVRAGVDAIQIFDSWLGYLSPQTYENYIKGHIEEILSEINVPVIYFSTGTSSIIEKLSRLNVDYISVDWRLDMKLARSMVNKKGLQGNLDPLIAAYNLRYALKETSDIINAAGRSSYIFNLGHGVIPETPVENLKHIVNFVHNFNQ
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_TOBAC
Sequence: MARSLCFMAFAILAMMLFVAYEVQARECKTESNTFPGICITKPPCRKACISEKFTDGHCSKLLRRCLCTKPCVFDEKMIKTGAETLVEEAKTLAAALLEEEIMDN
What is the function of this protein?
Involved in floral organogenesis.  May play a protective role in flowers by protecting the reproductive organs from potential pathogen attack.
What are the official names of this protein?
Defensin-like protein, Flower-specific gamma-thionin.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted, cell wall. Vacuole. Note=Possibly the cell wall or vacuole.
Protein: HTPX_METPP
Sequence: MFNLMKTAVLMAAITALFMAIGSVLGGQQGMAIALVVALGMNFFSYWFSDKMVLKMYNAQEVDASSAPQFYGMVRELAAKAELPMPKVYLINEDAPNAFATGRNPQNAAVAATTGILRVLSERELRGVMAHELAHVKHRDILISTISATMAGAISMLANFAMFFGGRGSDGRPANPIAGILVMLLAPLAASLIQMAISRAREFEADRGGAEISGDPQALASALQKIQRYAQGIPLEAAERHPETAQMMIMNPLSGGGLRGLFSTHPATEERVAKLMAMVPQRV
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.