PharMolix/UniProtQA huggingface dataset:
Protein: OMA1_YEAST
Sequence: MLRNIIRFKGFGKGTSGGFLKPVSFRVQLTRCYRYDNGPSYRRFNNGEYSQKSSFKSILLDKSSRKYLALLFGGCSLFYYTHLDKAPVSDRSRFIWVSRPLELTIGNYTYKSIWRQTQQEILPPQHPLSIKIENIFMKIVEAAYKDPSVDNSLLDGIKWEIHVVNDPTASPNAFVLPGGKVFIFSSILPICANDDGIATVLAHEFAHQLARHTAENLSKAPIYSLLGLVLYTVTGAHAINNILLDGFLRMPASRQMETEADYIGLMIMSRACFQPQESIKVWERMANFEKQMNRGGVVNMEFLSTHPASTRRIENMSKWLPKANEIYEQSDCSSMGNYYKSFFSM
What is the function of this protein?
Protease that is part of the quality control system in the inner membrane of mitochondria (PubMed:12963738, PubMed:22219186, PubMed:24648523, PubMed:27325672).  Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OXA1 and COX1 (PubMed:12963738, PubMed:22219186, PubMed:24648523).  Cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins (PubMed:12963738, PubMed:27325672).  Cleaves the misfolded multi-pass membrane protein OXA1 (PubMed:12963738).  Involved in quality control of cytochrome oxidase assembly: mediates the cleavage of COX1 in cells lacking COA2 (PubMed:22219186).  Required for the stability of the respiratory supercomplexes (PubMed:26365306).  Required for TOR signaling (PubMed:27325672).
What are the official names of this protein?
Mitochondrial metalloendopeptidase OMA1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: S26A1_MOUSE
Sequence: MDASPEPQQKGGTLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPAIHWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFDPSQDSLGPKNNDSTLNNSATTLIIGLQDCRRDCYAIRVATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHMLGVQIPRHQGLGMVVHTWLSLLQNVGQANICDVVTSALCLGVLLAAKELSDRYRHRLKVPIPTELFVIVVATIVSHFGQLHTRFDSRVAGNIPTGFVAPQVPDPKIMWRVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSPADALVWVATAATCVLVSTEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEGLLPPPEVRVFRFTGPLYYANKDFFLRSLYRLTGLDAGHSATRKDQGPEVGVSNRSLVDGKDLGSVSSGAGLVVPLAFGFHTVVIDCAPLLFLDVAGMATLKDLRRDYRALDITLLLACCSPSVRDTLRKGGFLGEEQGAENELLFPSVHSAVEAACARREELLAADSAL
What is the function of this protein?
Sodium-independent sulfate anion transporter (PubMed:12590734, PubMed:12217875, PubMed:20160351, PubMed:27210743).  Can transport other anions including bicarbonate, thiosulfate and oxalate by mediating sulfate-hydrogencarbonate, sulfate-oxalate and oxalate-hydrogencarbonate anion exchange (PubMed:12590734, PubMed:12217875, PubMed:20160351, PubMed:27210743).  Mediates sulfate-thiosulfate anion exchange (By similarity).
What are the official names of this protein?
Sulfate anion transporter 1, SAT-1, Solute carrier family 26 member 1.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane.
Protein: THEM4_MOUSE
Sequence: MLRNCAMRLRTLGATPARRPGAARRLFSSEKVIRKDYALPNPSWTKDLRLLFDQFMKKCEDGSWKRMPSHRQNPTRAIQEFQTLFVDSKFKKEEQMSKAQQFTRSFEEGLGFEYAMFYNKVEKRTVSLFQGGLHLQGVPGFVHGGAIATIIDVTTGTCAISEGVAMTANLNITYKKPIPLLSVVVVNSQLQKIEGRKLFVSCTIQSIDEKTLYTEATALFIKLDPEKPLT
What is the function of this protein?
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism (By similarity).  Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity (PubMed:19421406).
What are the official names of this protein?
Acyl-coenzyme A thioesterase THEM4, Acyl-CoA thioesterase THEM4, Carboxyl-terminal modulator protein, Thioesterase superfamily member 4.
What is the protein family that this protein belongs to?
Belongs to the THEM4/THEM5 thioesterase family.
What are the subcellular locations of this protein?
Cell membrane. Cell projection, ruffle membrane. Cytoplasm. Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space. Note=Released from the mitochondria into the cytosol in response to apoptotic stimuli.
Protein: ERAP2_PONAB
Sequence: MLHSSAMVNSHRKSMFNIHKGFYCLAAILPQICICSQFSVPSSYHFSEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHQQIALLVPEKLMPHLKYYVAIDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESGHIALSNMPKVRTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSVSGITSSGVKVSIYASPDKQNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFASGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLTFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTHYLQHETSSPALLEGLSYLELFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDEGSVWDRMLRSALLKLACDLNHAPCIQKATELFSQWMESSGKLNIPTDVLKIVYSVGAQTAAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHVIARRPKGQQLAWDFVRENWTHLLKKFDLGSFDIRMIISGTTARFSSKDKLQEVKLFFESLEAQGSHLDIFQIVLETITKNIKWLEKNLPTLRTWLLVNT
What is the function of this protein?
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides.  Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules.  Preferentially hydrolyzes the basic residues Arg and Lys (By similarity).
What are the official names of this protein?
Endoplasmic reticulum aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: RS9_SALAR
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RS11_LEGPH
Sequence: MAITKSKQQKTRKKVKRVVSDGIVHIHASFNNTIVTFTDRQGNALCWATSGGSGFRGSRKSTPYAAQVATERAAAVAKEYGMKSVAVFVHGPGPGRESTIRELITQDFKIVEITDVTGIPHNGCKPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FOLD_SORC5
Sequence: MAAKILDGKAIAQKVRDEVREGVARFVAAHGRPPGLEVVLVGEDPASVTHTRSKERMSNEVGIRGRLRALPAATTEAELLACVAELDADDTVDGILVQLPLPARIRAHAVLDAIDPAKDVDGLHPVNAGLLAMGRPGGIAPCTPVGCMRLLAEAGVELAGARAVVVGRSNLVGRPMAQLLLARHATVAIAHTRTRDLKALCREADVLVVAAGKAKLIGGDWIKEGATVIDVGMNRDDAGKLVGDVDFDAVRERAAWITPVPGGVGPMTIASLLETTLRAAEARVAKR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: FENS_LAVPL
Sequence: MSSLVMHVGIVNKPAITYLPTLSRSASNLHNVSSTRLQTSCSLQLDYKPVDETRRSGNYQPSAWDFEYIQSLKNKYKEEKYLTRHTKLTVQVKMLLDEDMEAVQQLDFIEDLNNLGISYLFKDKITQILNHIYNEHRCFHNNEAEESDLYFTALGFRLLRQHGFKVSQEVFDCFKNEKYTNFKASLAGDTKGLLQLYEASFLLREGEDTLELARKFSTKLLQQKIDEGEPDNNLLSCIRHSLELPLHWRLQRLEARWFLDAYATRHDMNPIIFELAKLEFNITQATQQEELKDLSRWWNSTGLAEKLPFARDRIVESYFWAMGTFEPHQYGYQRELVSKIIALTTVVDDIYDVYGTLEELELFTDVIRRWETESIDELPYYIQLCYLAVNKFVFDLAHDVLKDKGFNSLPYLKRSWKDLIERYLIEAKWYHNRYTPSLEEYLNNARVTITCPTILSQIYFALASPIEKPVIEVMYKYHDILYLSGMLLRLPDDLGTAPFELKRGDVPKAVQCYMKERNVPEKEAREHVRFLIREASKQMNTAMAIDCPFTEDFAVAAANLGRVANLAYVEGDGFGVQHSNIYEHIGSLMFKPYA
What is the function of this protein?
Monoterpene synthase involved in the biosynthesis of volatile compounds widely used in aromatherapy and folk medicine, and present in culinary herbs (PubMed:24943828).  Mediates the conversion of (2E)-geranyl diphosphate (GPP) into alpha fenchol, limonene and alpha-pinene and, as minor compounds, into beta-myrcene, alpha-terpinolene and alpha-phellandrene (PubMed:24943828).
What are the official names of this protein?
(-)-endo-fenchol synthase, chloroplastic, Alpha fenchol synthase, LpFENS, Alpha pinene synthase, Limonene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MOCS3_DROAN
Sequence: MIDSEALENERTKLKREIAELRAALNRKEQCLRDLETTISEATGDEDDVHPDTNGGVCHTQLSNDDIARYSRQLILPDFGVQGQLRLKNSSVLIVGMGGLGCPAAQYLAAAGCGKLGLIDYDEVERSNFHRQILHSEARCGMSKAESARIALLELNQHCEIRCHTRLLNSRNAMHIIRTYDVVLDCSDNVATRYLLNDACVMLRKPLVSGSALKTDGQLTVYCYGNGPCYRCIYPVPPPPEAVTNCGDGGVLGAVTGTIGAMQALEAIKVIVGLGDVLAGRLLIFDGSSCLFRNIRIRSKRPNCHVCSAQPLITELIDYELFCGMHATDKDNPLQLLASEERLDVEEYRNKVQQQPHLLIDVRQPAEFEICQLPDAVNVPLAEVLDDSYLKRFSKQLEDTQLPIILLCRRGNDSQIAVQHVRNRFPKHSIRDIIGGLHAWTHKVDPSFPIY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A.  Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase MOCS3, Molybdenum cofactor synthesis protein 3, Ubiquitin activating enzyme 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MXT_DROME
Sequence: MAHTHLGRAVKNIEAPRPLKTQSRSSLKNSYLVIEELIQLIDNVTVGLQSCNTTPESITLLLHNLRVHGPQLEAVSKDTLDRAFVVFRNASQDERLNITTRLKLLELIELRAKSWDNDDTIAYYKSKQQISNVELPSEYQYDAGVQPGAFSTSPTFGVSGGVGGVNDGAAAAAAAVFNAASAAAAAQAAAIAAVGTSNQQHMLLPPGEVIRNSGKFPKPTKIPGKTYCKDEVVIRNADSGKVMGIKGRRVHMIEELSETIISFQRVNPGAKERLVQITGPAEDKINYAKQLMEDTIRRNASPVRLEPAPAVGGSCSSLNSSNSDDAIVQPRTPTGSSLANRLSFNSAQNFMTATAAAQQISQQMHHQTHHLQHQQQQQVAAVAAAAAAAAHAQATAAAGKVLRPNQQLLMHSYSTNDASVGEYKFTVNVGQHLIKITGDCCELVRVAKLVLDDYFSSSEFLASIEAGAAFDGTSLVTTPSTPLPGAGPPQFWLPGTDSGIGLNCVVSSSANNNGEGDDEVFAEPSNGGSSTSNQNGLARSRRSHFSRKESTPETKGAREKGDLDDLAGTNSLKSNASRVSYDIEHLLYYSMSPHSWTLPTDWQKMQETAPSILRNKDLQDESQRFDGDKYLASIKTAAKRDIVAADEVETLDE
What is the function of this protein?
Plays a role in promoting translation.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-binding protein Mextli.
Protein: AROE_GLUOX
Sequence: MIDGHTKLAGVMGWPVEHSRSPLMHNHWCRVNGVNGAYVPLPTHPHGFDQALRGLAAAGFQGVNVTIPHKEAAMLACDELTPTAKRAGAVNTICFVAGRIIGDCTDGTGFCDNLSAHDVAIAGRAMVLGAGGAARAVAAALLDRGCEVVIANRTLERAEALVEALGGGEAVAWYEWPSLLSGCSLLVNATSMGMGGKAGLDWDAALREAAPGLCVTDIVYTPRETPLLLAAQARGLRTVDGLGMLVHQARAGFRAWFGVDPQADRTTFDLLAASLRTDA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: M3OM1_PEA
Sequence: MDFSTNGSEESELYHAQIHLYKHVYNFVSSMALKSAMELGIADAIHNHGKPMTLPELSSSLKLHPSKVNILYRFLRLLTHNGFFAKTTVKSNEGEEETAYVLTPSSKLLVSGKSTCLSSLVKGALHPSSLDMWGVSKKWFHEDKEQTLFECATGENYWDFLNKDSDSLSMFQDAMAADSRLFKLAIQENKHVFEGLESLVDVAGGTGGVAKLIHEAFPHIKCTVFDQPQVVGNLTGNENLNFVGGDMFKSVPSADAVLLKWVLHDWNDELSLKILKNSKEAISHKGKDGKVIIIDISIDENSDDRGLTELQLEYDVVMLTMFLGKERTKKEWEKLIYDAGFSRYKITPICGFKSLIEVYP
What is the function of this protein?
Methyltransferase involved in the phytoalexin pisatin biosynthesis.  Has both 3- and 4'-O-methyltransferase activities.  Can use (+)-6a-hydroxymaackiain, 2,7,4'-trihydroxyisoflavanone and with much less activity (+)-medicarpin as substrates, but not (-)-6a-hydroxymaackiain, daidzein, formononetin or isoliquiritigenin.  May be involved in formononetin biosynthesis.
What are the official names of this protein?
(+)-6a-hydroxymaackiain 3-O-methyltransferase 1, Isoflavone 4'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: MOAE_HALVD
Sequence: MHVLGIVGAGATTLCDRLAAQLDGRVATVESLPESATEPESTDGVAAAYGLSPDGNWVGSGDDRDLDGLLDDLSAEYDYALLSGFPDARVPTVALAGVDAANVVAEAETADAADVASLAAEIDSHEPHVTLETLVERAKADPLEVYAGAIATFTGRVRAKESEDDDPTLSLEFEKYDGVAESKMDAISEELEARDGVLRVLMHHRVGVVEDGADIVFVVVLAGHRREAFRTVEDGIDRLKDEVPIFKKETTTDEEFWVHDR
What is the function of this protein?
Converts molybdopterin precursor Z into molybdopterin.  This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.  The sulfur is provided by the thiocarboxylated form of SAMP1 (Probable).
What are the official names of this protein?
Probable molybdopterin synthase, MPT synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MoaE family.
Protein: NDK_HALH5
Sequence: MERTYLMIKPDGVQRNLIGEIVSRFEKKGFTLIGAKLMTVTKEQAETHYAEHKERPFFGELVDFITSGPVFAMVWEGENVIATARKMMGATNPADAEPGTIRGDFGVQVAMNVIHGSDSPESAKREIDIFFDSSELNEYDKVVNRWV
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: NBP35_ASPFU
Sequence: MAPSVMEPVAAFDVPTKAAPNLVAPEPEHCPGPESEQAGKGDACAGCPNQAICASAPKGPDPDIPIITERLSQIRHKILVLSGKGGVGKSTFSSLLAHAFASNPESTVGLCDTDICGPSIPKMMGVESETIHVSNAGWSPVWVTDNLSVMSIQFMLPNRDDAIIWRGPKKNGMIKQFLKDVDWGDLDYLIVDTPPGTSDEHLSVNSLLKESGVDGAVIVTTPQEVSLLDVRKEIDFCRKAGIRILGLVENMRGFVCPGCSNTSEIFRATTGGGKRLAKKMGIPFLGSVPLDPRVGMACDYGESFVDNFPDSPASKAIKQVVRSVGEMLGEDPNTVLPPDENDMVE
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor nbp35, Nucleotide-binding protein 35.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y778_STAAB
Sequence: MAKKAPDVGDYKYGFHDDDVSIFRSERGLTENIVREISNMKNEPEWMLDFRLKSLKLFYKMPMPQWGGNLSELNFDDITYYVKPSEQAERSWDEVPEEIKRTFDKLGIPEAEQKYLAGVSAQYESEVVYHNMEKELEEKGIIFKDTDSALQENEELFKKYFASVVPAADNKFAALNSAVWSGGSFIYVPKNIKLDTPLQAYFRINSENMGQFERTLIIADEGASVHYVEGCTAPVYTTSSLHSAVVEIIVHKDAHVRYTTIQNWANNVYNLVTKRTFVYENGNMEWVDGNLGSKLTMKYPNCVLLGEGAKGSTLSIAFAGKGQVQDAGAKMIHKAPNTSSTIVSKSISKNGGKVIYRGIVHFGRKAKGARSNIECDTLILDNESTSDTIPYNEVFNDQISLEHEAKVSKVSEEQLFYLMSRGISEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEDSIG
What are the official names of this protein?
UPF0051 protein SAB0778.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: RL28_MOUSE
Sequence: MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVMKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMAAIRRASAILRSQKPVVVKRKRTRPTKSS
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
60S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL28 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_SPHAL
Sequence: MTVVTITPGAMSFADWRAIYEGASAALTVGAWDAIDASAAAVARIVAKGDPVYGINTGFGKLASVRIASDDLATLQRNIVLSHAAGTGAPSPTPVVRLMMALKLASFGVGASGVRRETAAMLEAMLARGLIPVVPSQGSVGASGDLAPLAHMAAAMIGVGKIDVGGAIMPAAEALAQAELTPLELGPKEGLALLNGTQFSTANALAGLFRAETLFRSALITGALSTEAAKGSDAPFDPRIHALRGHIGQREVGGALRTLMAGSAIRASHAIDDPRVQDPYCLRCQPQVMGAVLDLLRQAGATLGVEANGVSDNPLIFADSDEALSGGNFHAEPVAFAADMIAIALCEIGSIAERRIAMLVDPALSGLPAFLTPRPGLNSGFMIPQVTAAALVSENKQRAYPASVDSIPTSANQEDHVSMAAHGARRLLDMADNASAVIGIELLAACQGIDFHAPLKSSDALEAAHRHLRSHVPTLDDDRHFHPDMEAATALIRSGSLVAAVPASLPGVG
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_LACLE
Sequence: MREKTPKQIVDLLDKYIVGQNEAKKSVAIALYNRYRRAQLPEDVQKDITPKNILMAGPTGVGKTEIARRLADIVDAPFVKVEATKFTEVGYVGRDVESMVRDLANEAVRIVEKEEFVKVEGQAIRQANKTLVRLLVPGVKRNNRQNQMQQMQEMIQSLLAGGGMSEETEEVTDEIRNQRLSVAEKLDRGLLENEEVTIEVEQAPKANPMGDMMGQMGMDMSSMLGDMLPKKKVKRTLPVSQARKLLVQEEEKKLVNYDDIYQKAMDRAGQSGIIFIDEIDKITAADKRNSAGVSREGVQRDILPIVEGSTVSTKYGPLSTDHILFIAAGAFAESKPSDLIPELQGRFPIRVELDALTKDDFVRILKDPQNSLLKQYIALLKADGVDLVFTAEAVDKIAEIAFEVNQGTDNIGARRLATILEKLLEEVLYEGPDMEMGQITITQAYVEQKLSDIVKNKDLTKFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXS1D_CUPSA
Sequence: GFGSLFKFLGKKVLK
What are the official names of this protein?
Short cationic peptide-1d, SCP-1d, Cupiennin 1-like peptide-1d, Truncated variant of Cupiennin 1 family.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TATC_DEIRA
Sequence: MTQLPPPEQTVLKPAPPELASAPLFDHLEELRRRLILSVVFLAVGMVIAFTYRVQLIELVKVPLTYSELYTTGKVQLVTTKLASQLLLSFNLAFWAGLTLALPFIVWQIWAFIAPGLYPQERRWGLPFILGAGFAFAAGVVFGYKLVLPTMVPFLIEFLAGTVTQMQDLQEYIGTVVTFLVAFGVAFELPILAVILTRLGIVNHTMLRQGWRFALIGIMILAAVITPTPDPANMALVAVPLYALYELGVVLSRVFRVIAPEEQERPAPMS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.
What are the official names of this protein?
Sec-independent protein translocase protein TatC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SECM_SALTY
Sequence: MSGILTRWRQLGRRYFWPHLLLGMVAASFGLPALSNAAETNTPARTTASTASKVNFSHFALLEASNRRPNFTVDYWHQHAIRTVIRHLSFAMAPQTLPVADAPSPLQAHHIALLNTLSAMLTQEGTPPAIVRRLSLAYFAPQTAFSIPAWISQAQGIRAGPQRLS
What is the function of this protein?
Regulates secA expression by translational coupling of the secM secA operon.  Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
What are the official names of this protein?
Secretion monitor.
What is the protein family that this protein belongs to?
Belongs to the SecM family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Periplasm. Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease.
Protein: ACPS_BRUSU
Sequence: MIVGIGSDLIDIRRVEKTLERHGSRFRDRVFTEIEQRKSEGRKQRAASYAKRFAAKEACAKALGTGIAEGVFWRDMGVVNTPSGKPTMHLTGGAAKQLQKLLPAGTNAAIHLTITDDFPLAQAFVIIEALPVLE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLTPF_ARATH
Sequence: MSKSIFVVCITLLVVLSPTLNAKMVTYPNGDRHCVMAQGQVISACLQQANGLPHADCCYAINDVNRYVETIYGRLALCKCFQEILKDSRFTKLIGMPEKCAIPNAVPFDPKTDCDRFVEHIWLKMF
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).
What are the official names of this protein?
Non-specific lipid-transfer protein 15, LTP 15.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: SNX17_HUMAN
Sequence: MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQEFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDELMVKKSGGSIRKMLRRRVGGTLRRSDSQQAVKSPPLLESPDATRESMVKLSSKLSAVSLRGIGSPSTDASASDVHGNFAFEGIGDEDL
What is the function of this protein?
Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels (PubMed:15121882, PubMed:15769472).  Binds to NPxY sequences in the cytoplasmic tails of target cargos (PubMed:21512128).  Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits (PubMed:28892079, PubMed:22492727).  Also required for maintenance of normal cell surface levels of APP and LRP1 (PubMed:16712798, PubMed:19005208).  Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (PubMed:16712798).
What are the official names of this protein?
Sorting nexin-17.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.