PharMolix/UniProtQA huggingface dataset:
Protein: NCOA2_XENLA
Sequence: MGENLSDPSRAEPRKRKESLDQLGPSPKRSTEKRNREQENKYIEELAELIFANFNDIDNLNFKPDKCAILKETVKQIRQIKEHEKTAAANEDEVQKADVSSTGQSVIDKDALGPMMLEALDGFFFVVNREGNVVFVSENVTQYLRYNQEELMNTSVYSILHVGDHSEFIKNLLPKSLVNGVPRRNSHTFNCRMLVKPMMECEEERHDGQETHQKYESMQCFAVSQPKSIKEEGEDFQSCLICVARRVPVKERPVPPPSESFTTRQDFQGKITSLDTTSMRALMRPGWEDMVRRCIQRFHSQHDGEISYSRRHHQEVLRQGHATSPFYRFSLSDGTTVVAQTKSRLMRSQTNNEPPLVLSLHVLQREQNVCGLNQDLAGQAMGKTLNPVQSSSPAHQAMYGGNPGQDTTISSNMNYAISGPKEQMGLATGRFVGSGGMNHISSLQATTPQGNNYALKMNSPSHGSPGMGQGQPNSMLSPRHRVSPGVAGSPRIAPSPFSPAGSLHSPVSVCSSTGNSHSYTNSSLNALQALSEGQGPLAPPLSSPDLKGGNLQHSPGNMNPPQLRKMGSIDSKESFGLYEEQPESATGQGESGCHSNEQKDCGENLSSVVDKTEGQSRLLDGKGQQKLLKLLTTKSDQMEPSTLPSNTLGDMNKDSLSNFASNSMSASAHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKELSQESNSTGPGSEVTIKQEPVSPKKKEHALLRYLLDKDDTTDNVADITPKLERADNKVDPSSCPKLSAVKAEKEEPNFGHTDQPGSDFDNLDEILDDLQNSQLSQLFSDTRHDGNSADKQAIMNDLMQLAGENSTGLPAWAQKQRMLRMQQNNGFNSQLAAQLGRLPNQNLPLDIHFQSQASAGSFAQMRSSGPYTTVPQSGVINNQAMMGSQGNVRNSSPGIVGVNGPRPPLKPGDWGSQASAVRPACPTTSTAMNRHDMSRSPTASIPMRPGSQVCPRQVLQSAVMNMGSSELDMNISGPQYTQQQAPPNQTAPWPNRILTIEQPSFNNQNRQPFGSPADDLICQPIVSESPADDGNLLDQLYMALRNFDGLEEIDRALGIPEMVSQGQAVEQESFGSPESNLMMEQKPPVYNHAYANQGQMAQNSYQPMQDPGFNPMGQRPSYGILRMQNRPGLRPTGMVQNQPNQLRLQLQHRLQAQNRQQLMNPINNVSNMNLAMRPGVPGQLREQGPINAQMLAQRQREILSQHLRQKQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHRAMMMRSQGLAMPPNMVGSGGIPASINSPRIPQGSTQQFPFPPNYGTGIPSPPPFTSPFSPVPPSPGSQSLSHSSLHGSQMNLANQGIMGSMGGQYGPVMNPQMQHNAFQFANSGMSQQSDPGFTGATTPQSPIMSPRMGHIQSSMMQQSQANPAYQSELNGWAQGNPAGNSMFSQQSPPHFGQQSGTSMYNSNNMNISVSMAANGNGMNNMNQMTGQINMTSVTSVPTSGLSSMGPEQKYC
What is the function of this protein?
Transcriptional coactivator for steroid receptors and nuclear receptors.  Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1) (By similarity).  Required in a nuclear receptor pathway to suppress expression of dorsal mesoderm genes.  May play a role in the positive regulation of the circadian clock (By similarity).
What are the official names of this protein?
Nuclear receptor coactivator 2, NCoA-2, Transcriptional intermediary factor 2, xTIF2.
What is the protein family that this protein belongs to?
Belongs to the SRC/p160 nuclear receptor coactivator family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAJ_BARHE
Sequence: MKVDYYEILGVTRECDDKKLKSAFRKLAMQYHPDRNAGDKEAERKFKEIGEAYEVLKDPQKRAAYDRFGHAAFENNNNGGGSPFSGFSAGGFADIFEDFFGEIMGGGHRKRSDGRERGADLSYNMEVTLEEAFSGKTAQINIPSSVVCDACEGSGAKKGSKPQTCGTCHGAGRVRAAQGFFSIERTCPVCHGRGETIKDPCPKCQGTRRVEKNRSLSVNIPAGIEDSTRIRLSGEGDAGIRGGPSGDLYIFLSVKPHEFFQREGADLHCRVPISMVTAALGGEFEVSDLDGIKARVKIPEGTQNGRQFRLKGKGMPMLRRQQVRGDLYIHITIETPQKLTQEQRELLQKFEKLSNHENSPQSHGFFSRMKEFFENISGKNE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_PSEMY
Sequence: MTDRTEAVKAYLLDLQDRICAALEAEDGQALFREDAWQRPAGGGGRTRVIENGALIEKGGVNFSHVFGDSLPPSASAHRPELAGRGFQALGVSLVIHPENPYVPTSHANVRFFSAEKEGEEPVWWFGGGFDLTPYYANEEDCRYWHQVAFDACAPFGAEVYPRFKAWCDRYFHLKHRGEPRGIGGLFFDDLNEWDFDTCFAFMRAIGDAYIQAYLPIVQRRKLTPFGEREREFQAFRRGRYVEFNLVFDRGTLFGLQSGGRTESILMSLPPMVRWGYDWKPEPGSEEARLTEYFLTDRDWLSGA
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_BACAC
Sequence: MWNEFKKFAFKGNVIDLAVGVVIGAAFGKIVSSLVKDIITPLLGMVLGGVDFTDLKITFGKSSIMYGNFIQTIFDFLIIAAAIFMFVKVFNKLTSKREEEKEEEIPEPTKEEELLGEIRDLLKQQNSSKDRA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UNG_BUCAT
Sequence: MILSWKDVLSQEKKKKYFINIIRFLKKERLKKIIYPDQKDIFNAFFLTSFNDIKVVILGQDPYFSKNQAHGLSFSVPKHVTIPPSLKNIYKELNTDFKKEHIFHHGCLESWANQGVFLLNSILTVESGKPKSHSNIGWNIFTDKVISVINLYKNSVVFLFWGSNAQKKSHLINRKNHYILKAAHPSPLSAYRGFFGCKHFSLTNKILLKTKKKPINWFLI
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_PROM0
Sequence: MINQENNDLYDLNEALQVENLTLNDYEEICKRLKKKPNRTELGMFGVMWSEHCCYRNSKPLLSKFPTKGKNVLVGPGENAGVIDVGNNQKLVFKIESHNHPSAIEPFQGAATGVGGILRDIFTMGARPIAVLNSLRFGNLDKSSNVDLLRGVVSGIAHYGNCVGVPTVGGEIDFDDSYSGNPLVNVMALGLLETEEIVCSGAKNVGSPVLYVGNTTGRDGVGGASFASSELTTTSLDDRPAVQVGDPFVEKSLIEACLDAFKTGDVIAAQDMGAAGLTCSSAEMAANGNLGISIDLDLVPSREDDMSSYQYLLSESQERMLFVVKEEKINDLIEKFNKWGLYASVIGEVIGTNEVIISHKGKIVAQIPTSALSDDTPVNFHNVINNPPDDLLNKWEWKENDLPEIHEQKIFSLKENKKFSFQEIILKLLSNPSIASKRWIYKQYDSQVQANTVFKPGKSDAAVVRLREQYKKNKSKVFSGVAASVDCNSRWVALDPFRGSIAAVAESARNVSCVGAEPVAITNNLNFSSPESEIGYWQLSSSCNGITEACKALETPVTGGNVSLYNESKNKDNLITPINPTPVIGMVGKIDNIEKAISCEWKNIDDQIWLIGSYKSDTTIAASSYLEYFHGEITGRPPKIDLLDEKFCQSFLRNAILNSLVVSSHDISDGGLAIALAESCILSAKGATIELKKDINREDNLLFAEGGSRIIFSINKIKQNEWLNYLKQNQINFPSSVYVKKIGHVSSETLKINIQDKNICNIRVEELSEKFNNSISDYF
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_WOLSU
Sequence: MHKTAIYPGTFDPLTNGHMDIIRRASMIFDTLIVAVAKSATKEPMFPLSEREEMLRLATRECPSVRVESFDTLLADFAQERGACILVRGLRAVSDFEYELQMGYANASLNPALETIYLMPSLQNAFISSSVIRSILLHKGKISHLVPPVVCEYIQKRRSCM
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRD_PSEA8
Sequence: MMAAQPTIREVLFNPVFQNNPIGLQILGICSALAVTSNLKTATVMAIALTLVTGFSNLFISMIRRQIPSSIRMIVQMVIIASLVIVVDQVLKAYAYSLSKQLSVFVGLIITNCIVMGRAEAFAMANPPLVSFFDGIGNGLGYSAMLLVLGFVRELFGAGKLYGISVLPTVNDGGWYQPNGLLLLPPSAFFLIGLIIWALRTWKKDQVEAPTYKMAPQVSSKEAY
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MED23_RAT
Sequence: METQLQSIFEEVVKTEIIEEAFPGMFMDTPEDEKTKLISCLAAFRQFWNGLSQESHEQCVQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRVPLPGTSCLASASVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHTKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSHRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMTFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMTDENEIITQFSMQGFPPLFLCLLWKMLLETDHISQIGYKVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQSDWHTKHMSYHKKYPEKLYFEGLAEQVDPPVPIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMCLRNRDHLKRKLVHAIIGSLKDNRPQGWCLSDTYLKHAMNAREDNPWVPEDSYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSSSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPVVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAVPPQALSSGSPAPQANQVPTALPVTQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.  Also required for transcriptional activation subsequent to the assembly of the pre-initiation complex.  Required for transcriptional activation by adenovirus E1A protein.  Required for ELK1-dependent transcriptional activation in response to activated Ras signaling (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 23, Cofactor required for Sp1 transcriptional activation subunit 3, CRSP complex subunit 3, Mediator complex subunit 23.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 23 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRIN_SULTO
Sequence: MTITKRKNTFYTSQFISYMKGYYLHPDIRGNLVAFTSDDDVWLMTLEDMKPIRVTSGQGVAIRPKISPDGKKIAYTIIWLRKGKGGGDIFITGNGETKRITFFGSMNTRVLGWLSDDEILVLTDFHTPFPQWSETYKININDGTMEKIPFGPISNIAISGDIIVIARGYQDLPFWKGYKGGTKGEFLISYDKGNT
What is the function of this protein?
Degrades oligopeptides in a sequential manner.
What are the official names of this protein?
Putative Tricorn-like protease N-terminal subunit.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBH_OENEH
Sequence: MATQTAEESSRARPKKTGLGGLLKPLNSEYGKVAPGWGTTPLMGLAMALFAVFLSIILEIYNSSVLLDGISMN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GLPK_GLOVI
Sequence: MVFASAGAAVSGAILALDLGTTGIRALLFDPSGAVAAGAYREVPQIYPQPGWVEHDPQTIWQLTCEVVAEVQAQSAARIAAVGLTNQRETCLLWDAATGTPHGNAIVWQDRRTAALCQKLRAEGWEAPIRQRTGLVIDAYFSATKLAWLLAHRRPYYPGLKAGTIDSWIIWKLTGGRVHATDTSNASRTMLFNLHTRDWDPELLELLAIPAEILPAIKPSLGVLAETDVRVLGYSAPIAGILGDQQAALFAHGCDRPGLVKCTYGTGSFLVAHTGDRPIRSRHQLLTTVAWSDRTSTGYALEGALFTTGASVQWLRDGLGIIETADESEALAASVPDSGGVYFVPALSGLGAPHWDMGARGLLIGLTRGSGRGQIARAVLEAIAFQTREVTDALAADMGTPLTRLKVDGGAVRNNLLMQLQADVLGVPVERPQLIDTTAQGAAFAAGLGTGFWGDYAELVAARPIDRVFESGERQLVLQAHYAVWQRAVERSREWVR
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RL3_YERPA
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEIEANRVTQVKSLENDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLPEGQEFTAGQEISVEIFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGHMGDERVTVQSLDVVRVDAERNLLLVKGAVPGATGGNLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SYH_ALKEH
Sequence: MAKGIRSIRGFSDILPEQTPLWQFVESNIQATLEAYGYREIRLPIVEKTELFSRSIGEVTDIVEKEMYTFEDRNGDSLTLRPEGTAGCVRCGIQNGLFHGGQPRVWYAGPMFRHERPQKGRYRQFHQIGAEVYGESGPGVDAEMILMTARLLRCLGLEDVRLELNTLGTGEARAAHRAALVEYLQAHEDRLDDDARRRLHSNPLRILDTKNPDMQALVEQAPRLMDYLDEDSRSHFQAVCRVLDQAGVAYRVNPRLVRGLDYYSRTVFEWITDRLGAQGTVLAGGRYDTLVEQIGGKPTPAIGFALGLERLVSLLEESGISGPQSGPHAFVVSADSLRALPLVEGLRDRLPGLRLQMQTEGGSFRSQFKRADRSGAALALVLGEEELAEGRFGVKDLRGDAEQQRLDPEALSDYLARRWPELAATEVTD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_ACHLI
Sequence: MMIKQAEFITSAVSITDLPKDDFDHFLILGRSNVGKSSLINAITNRKKLARVSQTPGKTITLNLYLLNQSLYLVDAPGYGYAKRSKTQTLTFMRMINEYIQLNGHLKKIILLVDFNIGPTQDDLDMYIELQAFDVDIIVVTTKYDKVKSSHRLKQEKVIRSKFFEGQKIYFTSSETKFGIDKLINEEFSNE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SELU_SHEB9
Sequence: MPNAIVAAEQYREIFLNQHPIMDVRAPIEFTRGAFPNSTNLPLMLDSEREKVGTCYKQSGQQAAIALGHSLVNGPIKQQRIEAWASYVKANPKAYLYCFRGGLRSQLTQQWLKEAGVEVPYIQGGYKAMRQYLIGVIEAAPAQQPLLSLSGMTGCGKTDFLLLRKEAVDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLQHQTSGVACLLLEDESFLIGRSALPQTFYNAMQAANVLVLEESDDVRLERLRDEYVHKMYSGFCERLGAEAGFAAFSDYLLQSLVSIRKRLGGKQHQELQDLMQQALDQQINQNDTSLHLVWINLLLHKYYDPMYLYQLQNKSERVLFKGSHQAMHEWLDSYQTR
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: EFTU_CHLMU
Sequence: MSKETFQRNKPHINIGTIGHVDHGKTTLTAAITRALSGDGLADFRDYSSIDNTPEEKARGITINASHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSATDGAMPQTKEHILLARQVGVPYIVVFLNKIDMISEEDAELVDLVEMELSELLEEKGYKGCPIIRGSALKALEGDAAYIEKVRELMQAVDDNIPTPEREIDKPFLMPIEDVFSISGRGTVVTGRIERGIVKVSDKVQLVGLRDTKETIVTGVEMFRKELPEGRAGENVGLLLRGIGKNDVERGMVVCLPNSVKPHTQFKCAVYVLQKEEXGRHKPFFTGYRPQFFFRTTDVTGVVTLPEGVEMVMPGDNVEFEVQLISPVALEEGMRFAIREGGRTIGAGTISKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BRUMB
Sequence: MARVKRGVTAHAKHKKVLDQAAGFRGRRKNTIRTAKAAVDRSKQYAYRDRKNRKRSFRALWIQRINAAVREQGLTYGRFIDGLAKAGIEIDRKVLSDIAIHEPEAFAALVASAKKALEYLKNTSMPNAFEGAVR
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: UVRC_STRPB
Sequence: MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCFYYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGTSPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_ALISL
Sequence: MKIKALSKLKPEEGIWMTEVEKPEMGHNDILIRIKKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVRGFEIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRTGAFSEFLVIPAFNAFKIPAGISDDLASIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVAKHVGARHVVITDVNEFRLDLARKMGVTRAVNVMNEKLEDVMSDLGMTEGFDVGLEMSGNPSAFNSMLTNMNHGGKISLLGIPPSDMAVDWNQVIFKGLVIKGIYGREMFETWYKMASLIQSGLDLTPIITHHYKIDDFQAGFDMMRSGMSGKVILDWE
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_EHRCR
Sequence: MLSVILKESVRNLGKAGMVLKVKPGYARYLLTQKKAVRATKENLKSLEEQYLFIEKENLEKLEAAKVLKASLEDEFLIITRQAADDGKLFGSVTPKCISKLLSDKGYNIHYRNIFFYSVIKYIGEYVVNLELHPDLVLPITLYVVKNDLGAMQAQKLHAEKKRKIEEGKVEKGSCTEGESLELGSVDNDINSGNVDSNESEKQDSVSE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: P34_RICPR
Sequence: MNNSHHRLIKSVSYLSVTTALIILIIKLYAWVVTSSQSILASLIDSMLDITSSFINLVALRFALQPPDHYHRFGHEKMQDLTIFSQSIFFFASAFFVGFASVKSLFIKTKPENISDGTIIMYLCMFLTIILVLYQTYVIKKTGSEIVKADKLHYFTDLLTNVIVIISINLSDYFWFVDPLFGVVISLYIFHSSYSLFKKAFKNLVDHELPEQDRQKIISIVNNHSGVKGMHEMKTRYAAQKAFIQCHLEMDGNISLYSAHKISDEIAFEILQKFPEAEIIIHQDPFGIEEHVNYREYIVR
What are the official names of this protein?
Protein p34.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF2_SHEPA
Sequence: MADTTVDKLATEVGKSTERLVEQFSQAGIKKSASDTVSETEKQQLLDFLKKQHGGDAAPTKMTLQRKSVSTLSVAGSGGQSKDVKVEVRKKRTFVKRDEAAEAELAAAAKAEEAKAAEAEAKAKAEAEAKAKVDAEAKVKAKAEAEAKAKAKVQTEKPAAETAEDKAAKAEEAKLLAAQDAVAKAKANEEASAAADEARRLAEENEKRWAEEEKARKEAEKSVDHHVTTSTEARAAEDTADANAEKRGRRPRKPSANAGNNANANAGAGKPGGKGKRGKDNRRDNRNSRNSRNTRSVAPESMDHAFTKPAAVVKAEVSIGETVSVAELASKMSIKATEIIKQMMKMGSMVTINQVLDQETAQLVAEEMGHKVILTRENELEHQVLADRNGDVKVEPRAPVVTIMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTAMRARGAKATDIVILVVAADDGVMPQTIEAIQHAKAGGVPLIVAVNKIDKPEADPDRVKSELSQHGVMSEDWGGNNMFVHVSAKDGTGIDELLEGILLEAEVLELQAVREGMAAGVVVESKLDKGRGPVATVLVQEGTLKQGDIVLCGLEYGKVRAMRDENGKAITEAGPSIPVEILGLSGVPSAGDEATVVRDERKAREVALYRQGKFRDVKLARQQKSKLENMFANMVEGEVQELNLVLKADVQGSLEAIADSLNSLSTDEVKVNIIARGVGGLTETDATLAAASNAIMVGFNVRADAQARKVVDSESVDLRYYSIIYQLIDEVRDAMSGMLAPEFKQEIIGLAEVRDVFKSPKIGAIAGCMVTEGTIKRSAPIRVLRDNIVIYEGELESLRRFKDDVSDVRNGMECGIGVKNYNDVRVGDQIEVFETVEIARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.