PharMolix/UniProtQA huggingface dataset:
Protein: CITD_ECO27
Sequence: MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDAIRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPC_PHOLL
Sequence: MIWLRSSVVLLIFLTLITGVAYPLLATGLSELMFPYQAQGSMVKQDGQTVGSELIGQPFTKAIYFQGRPSATVDYPYNTLSSGGSNLATTNPILDDEIKRRVEQLRQFNRQPDIPVPVDLVTASASGLDPHISPAAADFQAQRVADARHLPIKVIKQLIRDNIEHPPSEFLGEPVINVLKLNLALDNLPEKKQ
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DAPE_CELJU
Sequence: MTPPATPLTPTLQLAHDLIRCRSVTPEDDGCQELMIRRLEAIGFKTERLRFGEVDNFWAIRGGDGPILAFAGHTDVVPTGPETHWNNPPFEPTIIDGMLHGRGAADMKGSLASMVVACENFVARHPNHKGRIAFLITSDEEGPSINGTVKVVEWLEARHTKMTWCIVGEPSSTTRVGDVIKNGRRGSLGGVLKVKGIQGHVAYPHLADNPIHTLAPALAELAAEHWDNGNEFFPATSFQVSNINGGTGATNVIPGEVTVVFNFRFSTELTDAILRERTQAILDKHELKYELEWILSGQPFLTPRGDLVNAVVDAINTATGLDAELSTSGGTSDGRFIAPTGAQVVELGPINATIHKVNECISAEDLNKLTAIYERTLEILLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RNH2_CUPMC
Sequence: MARTKAAASSQLGLELTQTVAVVQRLCGVDEAGRGPLAGPVYAAAVVLNPARQIRGLADSKILSAEKREALFDRICDHALGWHIASASVEEIDSINILHASMLAMQRAVQGLAASGVIPDLVQVDGNRCPQVAFPVEAIVKGDAKVRAISAASILAKVARDRELLKLHQEYPEYGFDSHFGYPTPQHFTALEQFGATPHHRRSFAPVRKVLERGMVRTMSSEAPPF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_SALDC
Sequence: MISDIRKDAEVRMEKCVEAFKTQISKVRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMGPAVEKAIMASDLGLNPSSAGTDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKAISEDDDRRSQEEVQKMTDAAIKKVDAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_CORJK
Sequence: MKDRVVLAYSGGLDTTVAISWIAKERNAEVVCVSIDLGQGGEDMETVRQRALGAGAVESIVVDARDEFANDYCLPTIKANGMYMKEYPLVSAISRPLIVKHMADAAKEHGGTAVAHGCTGKGNDQVRFEVGFANTAPDLEIIAPVRDYAWTREKAIAFAEENGIPIEQSKSSPFSIDQNVWGRAVETGFLEDLWNAPTKDVYAYTEDPGLGQAPDEVIISFESGVPVAIDGKKVTVLEAIEELNRRAGAQGVGRLDMVEDRLVGIKSREIYEAPGAITLIRAHEALEAVTVERELARYKRGIDAEWSNQVYDGLWFSPLKRSLDAFIDSTQAHVTGDIRLVLHAGSITVNGRRSGKSLYDFNLATYDEGDSFDQSMARGFVELHGLSSKIAAKRDLAN
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP13_CHICK
Sequence: MQRAALFGGGDAQMAAGDLGELLVPYMPTIRVPKSGDRVYKTECAFSYDSPDSEGGLYVCMNTFLGFGREHIERHYRKTGQCVYLHLKRHVIEKVPGASGGALPKRRNAKLFLDLEANGDLSSDDFEYEDEAKLVIFPDHYEISLPNIEELPALVTIASDALLSAKSPYRKQDPDSWEEELQASKHAKSLVQLDNGVRIPPSGWKCSKCDLRENLWLNLTDGSVLCGKWFFDGSGGNGHAMEHYKETGYPLAVKLGTITPDGADVYSFDEEEPVLDPHIAKHLAHFGIDMLQMQVAENGLRDNDIKPRVSEWEVIQEAGVKLKPMYGPGYTGMKNLGNSCYLNAVMQAIFSIPEFQRAYVGNLPRIFDYSPLDPTQDFNTQMAKLGHGLLSGQYSKPPMKSELIEQVMKEEHKPQQNGISPQMFKAFISKDHTEFSSNRQQDAQEFFLHLINLVERNPVGSENPSDVFRFLVEERTQCCQSRKVRYTERVDYIMQLPVAMEAATNKDELIAYELKRREAEAARRAPPELVRAKIPFSACLQAFSEPTNVEDFWSSALQAKSAGVKTSRFASFPQYLVVQIKKFTFGLDWIPKKLDVSIDMPDFLDISHLRAMGLQPGEEELPDIAPPIIIPEDPKDRMMNNFVESLDIDESSVMQLAEMGFPLEACRKAVYYTGNLGAEVAFNWIIAHMEEPDFAEPLVVPVFGGAASSGVAGLGAVGLDNQPPEEMVSIIISMGFQRSLAIQALKATNNNLERALEWIFSHPELEEEDGEPALNVMDLENHTNANILAEARSEGPRIKDGPGRYELFGFISHMGTSTMSGHYVCHLKKEGRWVIYNDLRVCASERPPKDLGYIYFYHRIPS
What is the function of this protein?
Deubiquitinase that mediates deubiquitination of target proteins and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 13, Deubiquitinating enzyme 13, Ubiquitin thioesterase 13, Ubiquitin-specific-processing protease 13.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: KAD_ENTFA
Sequence: MNLILMGLPGAGKGTQAEKIIDTYGIPHISTGDMFRAAMKNETALGLEAKSYIDKGELVPDEVTNGIVKERLAEPDTDKGFLLDGFPRTLDQAKALDTMLKELNKKIDAVIDIHVEEDVLIERLAGRFICRTCGATYHKLFNPPKVEGTCDRCGGHEFYQREDDKPETVKNRLAVNIESSAPILAFYKEQGLMHTIDGNREIDTVFSDVKKIIDEN
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMCP_HALO1
Sequence: MVLGKVVGTVVASRKEPRIEGLSLLLVRACDPDGTPTGGAVVCADAVGAGVGEVVLYASGSSARQTEVTNNRPVDATIMAIVDLVEMGGDVRFRKD
What is the function of this protein?
Forms vertices in bacterial microcompartment (BMC) shells.  Expression of 5 proteins in E. coli (BMC-H (Hoch_5815), BMC-P (Hoch_5814), and 3 BMC-T (Hoch_5812, Hoch_5816, Hoch_3341)) forms 40 nm artificial BMC with a molecular mass of 6. 5 MDa.  There are 12 BMC-P pentamers per BMC.  The shell facets are 20-30 Angstroms thick, with 1 of BMC-T trimers protruding to the exterior.
What are the official names of this protein?
Bacterial microcompartment shell vertex protein, BMC-P.
What is the protein family that this protein belongs to?
Belongs to the CcmL/EutN family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: LGT_STRR6
Sequence: MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPDDILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLYIFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMYIEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMRTDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KYNU_PICST
Sequence: MSLEKAQELDTKYPTYKDEFAVPTFKSLGIETSQFNENTDSIYLCGNSLGLMPKSTKQAINDELNAWIERGVESHFNHPGQSEGKTPWVDIDLPLVPLVAPIVGAKENEVAVMGSLTSNLNALLINFYKPKDKRTKILFEKQAFPSDYYAFLNLVKLHGYDESHLVQLKVLPGNTYLTTEQIKKAVDDNIDELAMVCFPGIQYYTGQFFKIEEITNYVKNKGKNEIVVGWDLAHAVGNVPLKLHDWNVDFAAWCSYKYLNSGPGGIAGIYVHEQYTKDNSKTSFSPRLAGWWGNNASDRFKMLEEFDPINSALSYRQSNPSVIDVVAVKSSLELFKKVGGVPKLRKKSIALTQFLQDLLVSSKYYFRSDNDTDRSKIGFTILTPLNQEERGAQLSVLFQPHYDDKQKNIMERVSGYLHNHAIICDERRPDVIRFAPLPLYNTFEETYYAAQRLFEALDKISSEEI
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, Biosynthesis of nicotinic acid protein 5, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_THEPD
Sequence: MRAHIYVSGLVQGVFFRASMQEVARSLGVNGWVRNLPDGRVEAVLEGEEGAVLKVIEWARRGPPLARVERVDVEWEEYRGEFRDFYIKYR
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: ATPB_XANP2
Sequence: MANKVGRITQVIGAVVDVQFDGHLPEILNALETTNQGNRLVLEVAQHLGESTVRCIAMDATEGLVRGLEVTDTGAPIQVPVGAGTLGRIMNVIGEPVDELGPIEAEATRGIHQPAPSYAEQATEAEILVTGIKVVDLLAPYAKGGKVGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESNVNKDPHENGGSAAGSKCALVYGQMNEPPGARARVALTGLTVAEHFRDQGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTTKGSITSVQAIYVPADDLTDPAPAASFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLSPAILGDEHYNTARQVQQTLQRYKALQDIIAILGMDELSEEDKITVARARKIERFLSQPFHVAEVFTGSPGKLVDLKDTIAGFKGLVEGKYDYLPEQAFYMVGSMEEAIEKGKKLAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYC_BACC4
Sequence: MTIHIYNTLTRQKEEFVPLEENKVKMYVCGPTVYNYIHIGNARPPMVFDTVRRYLEYKGYDVQYVSNFTDVDDKLIKAANELGEDVPTIADRFVEAYFEDVTALGCKHATVHPRVTENMDIIIEFIQELVNKGYAYESEGDVYFKTKEFEGYGKLSHQPIADLRHGARIEVGEKKQDPLDFALWKAAKEGEIFWESPWGQGRPGWHIECSAMARKYLGDTIDIHAGGQDLAFPHHENEIAQSEALTGKTFARYWMHNGYININNEKMSKSLGNFILVHDIIKQYDPQLIRFFMLSVHYRHPINFSEELLQSTNNGLERIKTAYGNLKHRMESSTDLTDHNEKWLAEIEKFQTAFEEAMNDDFNTANAITELYNVANHANQYLLEEHTSKVVIEAYVKQLETLFDILGLELSKEELLDEEIEELIQKRIEARKNRDFALSDQIRDDLKERNIILEDTAQGTRWKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_ALBCA
Sequence: MTIYSYLLLLCMVMFVTFFTQKNNILSLMVVLESLMLITLSSVAVSLNYMAGSSMVMILLLCFAAAEAALSLSLLVCFIQVNSSCEMLAMNKILFAKKS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: BICC1_HUMAN
Sequence: MAAQGEPGYLAAQSDPGSNSERSTDSPVPGSEDDLVAGATLHSPEWSEERFRVDRKKLEAMLQAAAEGKGRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQNSERAHLAPRSSYVNMQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRSNSREHLGGGSESDNWRDRNGIGPGSHSEFAASIGSPKRKQNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELNKNRRKLFESPNARTSFLEGGASGRLPRQYHSDIASVSGRW
What is the function of this protein?
Putative RNA-binding protein.  Acts as a negative regulator of Wnt signaling.  May be involved in regulating gene expression during embryonic development.
What are the official names of this protein?
Protein bicaudal C homolog 1, Bic-C.
What is the protein family that this protein belongs to?
Belongs to the BicC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_ECODH
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RS4_THET2
Sequence: MGRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRPSDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRLDNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEKSRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQLVIEFYSR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the body and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ERP60_SCHMA
Sequence: MRWLLSCLFLVAFASCSKVLELTKDNFHSELKSIPVALVKFYAPWCGHCKKLAPEFTSAAQIISGKTNDVKLVKVDCTTQESICSEFGVSGYPTLKIFRNGDLDGEYNGPRNANGIANYMISRAGPVSKEVSTVSDVENVLSDDKPTVFAFVKSSSDPLIKTFMALAKSMVDDAVFCHSHNNLFVTPSDNELRVYLPKRLRTKFEDDFAVYKGELESNNIKDWIRKHGQGLVGYRSPSNTFYFENSDLVVLYNNQSIDSYPSGVKYLRNRVLKTLKDNPQKFKNLVFAYSFADDFSYEISDYGIEADKLPAVVIQSKDKKYKLEKFSLDAFSDFLNKFEDGLLTPHVKSEPLPTDDSSAVKKLVALNFDEIVNNEEKDVMVVFHAGWCGHCKNLMPKYEEAASKVKNEPNLVLAAMDATANDVPSPYQVRGFPTIYFVPKGKKSSPVSYEGGRDTNDIIKYLAREATEELIGYDRSGNPKKSEL
What are the official names of this protein?
Probable protein disulfide-isomerase ER-60, ERP60.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: COAX_XANOR
Sequence: MSEWLFDLGNSRFKYAPLHGNRAGQVQAWAHGAEAMDAAALAALPSGQIAHVASVAAPALTQRMIACLQERFTQVRIVRTAAECAGIRIAYADPSRFGVDRFLALLGARGDAPVLVAGVGTALTIDVLGADGLHHGGCIAASPTTMREALHARAVQLPASGGDYVELAIDTDDALTSGCDGAAVALIERSLQHAQRSLGAPVRLLVHGGGAPPLLPLLPGATFRAALVLDGLATWATAAASP
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL1_HPVME
Sequence: MALWRSSDNMVYLPPPSVAKVVNTDDYVTRTGIYYYAGTSRLLTVGHPYFKVPMSGGRKQDIPKVSAYQYRVFRISLPDPNKFSLPESTLYNPDTQRLVWACVGVEIGRGQPLGVGLSGHPLYNRLDDTENSPFSSNKNPKDSRDNVSVDYKQTQLCIIGCVPAIGEHWAKGKSCKPSNVQPGDCPPLELVNTPIQDGDMIDTGYGAMDFSTLQETKSEVPLDICQSVCKYPDYLQMSADVYGDSMFFCLRREQLFARHFWNRGGMVGDTIPTELYIKGTDIRDSPSSYVYAPSPSGSMVSSDSQLFNKPYWLHKAQGHNNGICWHNQLFLTVVDTTRSTNFTLSTTTESAVPNIYDPNKFKEYIRHVEEYDLQFIFQLCTITLSTDVMSYIHTMNPAILDDWNFGVAPPPSASLVDTYRYLQSAAITCQKDAPAPTKKDPYDGLNFWNVNLKEKFSSELDQFPLGRKFLLQAGVRRRPTIGPRKRPATATTASTSKHKRKRVSK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PHYC_ORYSJ
Sequence: MSSSRSNNRATCSRSSSARSKHSARVVAQTPMDAQLHAEFEGSQRHFDYSSSVGAANRSGATTSNVSAYLQNMQRGRFVQPFGCLLAVHPETFALLAYSENAAEMLDLTPHAVPTIDQREALAVGTDVRTLFRSHSFVALQKAATFGDVNLLNPILVHARTSGKPFYAIMHRIDVGLVIDLEPVNPVDLPVTATGAIKSYKLAARAIARLQSLPSGNLSLLCDVLVREVSELTGYDRVMAYKFHEDEHGEVIAECKRSDLEPYLGLHYPATDIPQASRFLFMKNKVRMICDCSATPVKIIQDDSLTQPISICGSTLRAPHGCHAQYMASMGSVASLVMSVTINEDEDDDGDTGSDQQPKGRKLWGLMVCHHTSPRFVPFPLRYACEFLLQVFGIQINKEVELAAQAKERHILRTQTLLCDMLLRDAPVGIFTQSPNVMDLVKCDGAALYYQNQLWVLGSTPSEAEIKNIVAWLQEYHDGSTGLSTDSLVEAGYPGAAALGDVVCGMAAIKISSKDFIFWFRSHTAKEIKWGGAKHEPIDADDNGRKMHPRSSFKAFLEVVKWRSVPWEDVEMDAIHSLQLILRGSLQDEDANKNNNAKSIVTAPSDDMKKIQGLLELRTVTNEMVRLIETATAPILAVDITGSINGWNNKAAELTGLPVMEAIGKPLVDLVIDDSVEVVKQILNSALQGIEEQNLQIKLKTFNHQENNGPVILMVNACCSRDLSEKVVGVCFVAQDMTGQNIIMDKYTRIQGDYVAIVKNPSELIPPIFMINDLGSCLEWNEAMQKITGIKREDAVDKLLIGEVFTHHEYGCRVKDHGTLTKLSILMNTVISGQDPEKLLFGFFNTDGKYIESLMTATKRTDAEGKITGALCFLHVASPELQHALQVQKMSEQAAMNSFKELTYIRQELRNPLNGMQFTRNLLEPSDLTEEQRKLLASNVLCQEQLKKILHDTDLESIEQCYTEMSTVDFNLEEALNTVLMQAMPQSKEKQISIDRDWPAEVSCMHLCGDNLRLQQVLADFLACMLQFTQPAEGPIVLQVIPRMENIGSGMQIAHLEFRLVHPAPGVPEALIQEMFRHSPGASREGLGLYISQKLVKTMSGTVQYLRESESSSFIVLVEFPVAQLSTKRCKASTSKF
What is the function of this protein?
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region.  Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses.  Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc.  It also controls the expression of its own gene(s) in a negative feedback fashion.
What are the official names of this protein?
Phytochrome C.
What is the protein family that this protein belongs to?
Belongs to the phytochrome family.
Protein: PYRF_NITWN
Sequence: MTGSHDSDLAREKLIVALDYWNIEDARKLVRDLGDGVSFYKVGLGLQLVGGNEFARELIAEGKRVFLDYKYYDIEETVQRAVAQAAELKIAFLTVHGVTSIMKAAVAGRGNSDMKILGVTVLTSMDAEDIKEMGFECSVEDLVVARARRALEVGVDGVVASALEAAELRKHTNNKLMIVSPGIRPSGGARHDQKRVATPFEAMRAGADYLVLGRPIYAADNPKAAAQAIIREMADALRPD
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: IF2_RHIEC
Sequence: MTDSNDDKTLSVTGKKTLTLKPSGMSQGTVRQDMGRGRTKAVVVETRKRRPMRPEDEKPITPATPAAPVRAAEPAPAPAQARPQQSTPAPRIHQPGGQANQRPQQSYQPPRANDRPRPVVLNHLSPEEMDARRRALAESQARDAQDAIRRAEEEKRRAAEEAVRKAAEAEEAARRAVEEAARQAEAAAAAAAEPAVTAPAPAPVTAEARPNTSPRPAAPAPAARRPDADGAAARPAPGAPAAVRGRRNDGDDDDRGASRGGPARGRVVRPEPAKPVTTRPKTDEERRRGKLTITTADVDGEDAGRSRSLSAMRRRQEKFRRSQVQETREKISREVVLPETITIQELSQRMSERAVDVIKYLMKEGQMMKPGDVIDADLAELIAGEFGHTVKRVSESDVELGIFNIADVEGDRVSRPPVVTIMGHVDHGKTSLLDAIRHANVVAGEAGGITQHIGAYQVEQNGQKITFIDTPGHAAFTAMRARGAQATDIAILVVAADDSVMPQTIESINHAKAAGVPIIVAINKIDKHEADPQKVRNQLLQHEVFVESMGGETLDVEVSAKTGKNLDKLLEAVLLQAEILDLKANPNRTAEGTVIEAQLDRGRGAVATVLVQNGTLKPGQIIVAGDVWGRVRALVNDKGEHMKEAPPAMPVEVLGLSGTPQAGDKFAVVESESRAREISEYRQRLARDKAAARQSGQRGSLEQMMTQMQSTGIKEFPLVIKGDVQGSIEAIAGALEKLGTDEVRARIVHLGAGGITESDISLAEASNAAIIGFNVRANAQARQFAERQGIEIRYYNIIYDLVDDVKAAMSGLLSPERRETFIGNAEILEVFNITKVGKVAGCRVVEGKVERGAGVRLIRNDVVVHEGKLKTLKRFKDEVSEVPMGQECGMAFENYEDMRVGDVIECFRVEHITRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2008_MYCTO
Sequence: MDEIESLIGLRPTPLTWPVVIAGDFLGVWDPPPSLPGAANHEISAPTARISCMLIERRDAAARLRRALHRAPVVLLTGPRQAGKTTLSRLVGKSAPECTFDAENPVDATRLADPMLALSGLSGLITIDEAQRIPDLFPVLRVLVDRPVMPARFLILGSASPDLVGLASESLAGRVELVELSGLTVRDVGSSAADRLWLRGGLPPSFTARSNEDSAAWRDGYITTFLERDLAQLGVRIPAATMRRAWTMLAHYHGQLFSGAELARSLDVAQTTARRYLDALTDALVVRQLTPWFANIGKRQRRSPKIYIRDTGLLHRLLGIDDRLALERNPKLGASWEGFVLEQLAALLAPNPLYYWRTQQDAELDLYVELSGRPYGFEIKRTSTPSISRSMRSALVDLQLARLAIVYPGEHRFPLSDTVVAVPADQILTTGSVDELLALLK
What are the official names of this protein?
Uncharacterized protein MT2064.
Protein: METJ_HAES1
Sequence: MADWDGKYISPYAEHGKKSEQVKKITVSIPIKVLEILTNERTRRQLRNLRHATNSELLCEAFLHAFTGQPLPTDEDLLKERHDEIPESAKQIMRELGINPDDWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.