PharMolix/UniProtQA huggingface dataset:
Protein: G1PDH_HALSA
Sequence: MFEKSTWIRLPRNVVVGHGVLDDAVEVVRDTHLTGRPLVVTSPTPKTVAAENVVAQFEAVGDDPAVVVVEEATFNSVERVLGEAEAVDPGYLVGVGGGKAIDIAKLASDHLNVGFVSVPTAASHDGIVSGRGSVPEGDTRHSVSAAPPLAVIADTGVIADAPWELTTAGCADIISNYTAVKDWRLANRLQHVPYSEYAGALSQMTAEMLVDNAANIKPELEESAWVVVKALVSSGVAMSIADSSRPASGSEHLFSHQLDRIAPGKALHGHQVGVGSILAEYLHSGQEGQWMAVRDALASLDAPTTADELGVADDEVLAALTSAHEIRDRYTILGGGISEVAAREAASRTGVI
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEUM_BUFJA
Sequence: MSYTALAVTFFGWLALSSACYIQNCPIGGKRSVIDFMDVRKCIPCGPRNKGHCFGPNICCGEELGCYFGTTETLRCQEENFLPSPCESGRKPCGNNGGNCARSGICCNHESCTMDPACEQDSVFS
What is the function of this protein?
Mesotocin is a diuretic hormone.
What are the official names of this protein?
Mesotocin-neurophysin MT.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AGRF1_HUMAN
Sequence: MKVGVLWLISFFTFTDGHGGFLGKNDGIKTKKELIVNKKKHLGPVEEYQLLLQVTYRDSKEKRDLRNFLKLLKPPLLWSHGLIRIIRAKATTDCNSLNGVLQCTCEDSYTWFPPSCLDPQNCYLHTAGALPSCECHLNNLSQSVNFCERTKIWGTFKINERFTNDLLNSSSAIYSKYANGIEIQLKKAYERIQGFESVQVTQFRNGSIVAGYEVVGSSSASELLSAIEHVAEKAKTALHKLFPLEDGSFRVFGKAQCNDIVFGFGSKDDEYTLPCSSGYRGNITAKCESSGWQVIRETCVLSLLEELNKNFSMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETIISMASLTLGNILPVSKNGNAQVNGPVISTVIQNYSINEVFLFFSKIESNLSQPHCVFWDFSHLQWNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSWKQTEKQNSSDLSAKPKFSKPFNPLQNKGHYAFSHTGDSSDNIMLTQFVSNE
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Adhesion G-protein coupled receptor F1, G protein-coupled receptor 110, G protein-coupled receptor KPG_012, G protein-coupled receptor PGR19.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: SCXB_RHOJU
Sequence: KEGYMGSDGCKMSCVINDQFCDTECQAKLKGSTGYCYFXGLACYXXG
What is the function of this protein?
Causes transient paralysis of the rear legs of and spasms in insects (A. domestica).
What are the official names of this protein?
Putative beta-neurotoxin.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NCBP2_ORYSJ
Sequence: MASLFKDPTKLSAYRDRRFTGTQEEYEAALQASVTVYVGNMSFYTTEEQAYELFSRAGEIRKIIMGLDKNSKTPCGFCFILYYSREDAEDAVKYISGTMLDDRPIRVDFDWGFEEGRQWGRGRSGGQVRDEYRTDYDPGRGGYGKMVQKELEAQRELVDYGGAFQPNAPPQYDRGDRKRGYGDSYRNDRDYQRKRYRNDERSSQRAPDSEFKRDAIDSEKNPRFREKGDSDEEDDDYDKRRRR
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs).  The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing.  In the CBC complex, CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ABH1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.  CBP20 also plays a role in stabilization of ABH1/CBP80 and ABH1/CBP80 localization to the nucleus (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Protein: CSRA_ACIBY
Sequence: MLILTRRVGETLMIGDQVSVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQHERAMHEHLQHLDQDYQVSYEDDNYAQKNFNR
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOSA_SULAC
Sequence: MLPKKKLHMKVGILDSTLREGEQTPGVVFTTDQRVEIAKALSDIGVQMIEAGHPAVSPDIYEGIRRIIKLKREGVIKSEIVAHSRAVKRDIEVGAEIEADRIAIFYGISDTHLKAKHHTTRDEALRSIAETVSYAKSHGVKVRFTAEDATRADYQYLLEVIKTVRDAGADRVSIADTVGVLYPSRTRELFKDLTSRFPDIEFDIHAHNDLGMAVANVLAAAEGGATIIHTTLNGLGERVGIAPLQVVAAALKYHFGIEVVDLKKLSEVASLVEKYSGIALPPNFPITGDYAFVHKAGVHVAGVLNDPKTYEFLPPETFGRSRDYVIDKYTGKHAVKDRFDRLGVKLTDSEIDQVLAKIKSNPNVRFYRDVDLLELAESVTGRILKPRPPENIMALISVKCDSNVYTTSVTRRIVLIEGVREVMEISGDYDILVKVEAKDSTELNQIIESIRAVKGVKSTLTSLILKKM
What is the function of this protein?
Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate.  Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.  Does not display 2-isopropylmalate synthase and citramalate synthase activities since it cannot use 2-oxoisovalerate or pyruvate as substrate.
What are the official names of this protein?
Homocitrate synthase, HCS.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
Protein: FER_WHEAT
Sequence: MAAALSLRAPFSLRAVAPPAPRVALAPAALSLAAAKQVRGARLRAQATYKVKLVTPEGEVELEVPDDVYILDQAEEEGIDLPYSCRAGSCSSCAGKLVSGEIDQSDQSFLDDDQMEAGWVLTCHAYPKSDIVIETHKEEELTA
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y772_SULIN
Sequence: MDYWFAEIVTIGNEVLSGKTVNTNASHIGRRLTSLGFTVRRITVVMDDIDEIVSAFREAIDRKPKVIVSSGGLGPTWDDKTAEGLAKALGVNLELNKTAFDMILEKYTKRNIPLTEERKKMAYLPYGAMAVENNEGIAPGIYIYHNNIDILATPGVPREMENVLENFINKMLRNKPNLKYLEDFIYVENVMESALAPYVKELVKKYDIYIKTHPKSYELLRPILEIQIAGSGREEEIKVKIEKVKNELLDAIKKLNGIIRNSL
What are the official names of this protein?
Protein YN1551_0772.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: OPGC_ECO57
Sequence: MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGTFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URE1_ACTPJ
Sequence: MALIIPRSQYVATYGPTVGDKVRLGDTDLWATIEQDFLTKGDECKFGGGKSVRDGMAQSSTATRDNPNVLDFALTNVMIIDAKLGIIKADIGIRDGRIVGIGQAGNPDTMDNVTPNMIIGASTEVHNGAHLIATAGGIDTHIHWICPQQAQHAIENGITTMIGGGSGPADGTHATTCTPGKFNIERMFQACEALPVNIGFFGKGNCSMLEPLKEQVVAGALGLKIHEDWGATPAVIDAALKVADEMDVQVAIHTDTLNESGFLEDTMKAINGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLPASTNPTRPFTVNTIDEHLDMLMVCHHLDKRVPEDVAFADSRIRPETIAAEDILHDMGVFSIMSSDSQAMGRVGEVVTRTWQTADKMKAQRGALGDEGNDNFRIKRYIAKYTINPAIAHGISQYVGSLEVGKLADIVLWKPQFFGVKPEFVMKKGFISFAKMGDPNASIPTPQPVFYRPMFGANAKANTESAVYFVSQASVDANIKAQYGIQKETLAVKGCRDVGKKDLVHNNATPEITVDPERYEVRVDGEHITCEPATKVPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX34A_PHOKE
Sequence: ATCAGQDKPCKETCDCCGERGECVCGLSYEGKYRCICRQGTFLIAWYKLASCKK
What is the function of this protein?
Blocks voltage-gated sodium channels (Nav).  Causes immediate spastic paralysis and death in mice within 1 min of injection at dose levels of 1. 5 ug per mouse.
What are the official names of this protein?
U7-ctenitoxin-Pk1a, U7-CNTX-Pk1a, Neurotoxin PKTx36C1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 04 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DCD_THEAC
Sequence: MILNDSTIMRMVSDGLLISENFDRGCLTPNGYDLRVDAIDVEGRQYSEFEIGKNVHFLVSTIEILKIPDDVVGMIWTRSSFARKGIFGSFGAIDAGYHGNLTLSFFNAGSAVNLRRGERIAQIVFVKMIGSAEKPYHIRSGNYQNSRGIVKDPVAGSQIASEAKKN
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: TRPD_CYTH3
Sequence: MKDLLQQLTSHYRLTKEEAKEAMLAIGNGKINAAQVAAFISVYMMRSITVAELQGFREALLEMCLDADLSEYDPIDIVGTGGDGKDTFNISTLSCFVVAGAGIKVAKHGNYAVSSSCGSSNVVEYLGYKFSNSKDVLRKQIEEANFCMLHAPLFHPALKNVAPVRKELGMRTIYNMLGPLVNPALPTYHLLGTFNMDLARLYGYIHQSLNSKFAIVHALDGYDEISLTGGFKVISNQLDRVLEPDDMGLHTYKAAELSGGKTVEDAAKIFIEVLENKSTRAQKEVVLANAGLAISIAKPDISLFDAIATARESLESGQAYECFKKAVK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: LRRN1_MOUSE
Sequence: MARLSTGKAACQVVLGLLITSLTESSILTSECPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPGNLSSDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQISEMTDYCLQDLSNLQELYINHNQISTISANAFSGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFRPLSNLRSLVLAGMYLTDVPGNALVGLDSLESLSFYDNKLIKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAVYQKTVESLPNLREISIHSNPLRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYRGQQVKEVLIQDSSEQCLPMISHDTFPNHLNMDIGTTLFLDCRAMAEPEPEIYWVTPIGNKITVETLSDKYKLSSEGTLEIANIQIEDSGRYTCVAQNVQGADTRVATIKVNGTLLDGAQVLKIYVKQTESHSILVSWKVNSNVMTSNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSNIHQQTQKSCVNVTTKTAAFALDISDHETSTALAAVMGSMFAVISLASIAIYIAKRFKRKNYHHSLKKYMQKTSSIPLNELYPPLINLWEADSDKDKDGSADTKPTQVDTSRSYYMW
What are the official names of this protein?
Leucine-rich repeat neuronal protein 1, Neuronal leucine-rich repeat protein 1, NLRR-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: YCY0_YEAST
Sequence: MPLFLVLKATLSENVTKVSIENTNESRAEFAFDLQCTSCRELHDSKVIINTFEEYAMPASKGTASFLMKCKFCSKELSVNLCAFEDEYLTDQSDDKWAKIKDVRKKHGLSKVKEDSFIPLSLDCRGCELIKFYPDTITFEVSLSSGKVMSCQLEDNEWYDYDDNLGEEVTMTDFSSSIIKGK
What are the official names of this protein?
UPF0587 protein YCR090C.
What is the protein family that this protein belongs to?
Belongs to the UPF0587 family.
Protein: AIM24_ARTOC
Sequence: MRRLIPGSGFRPSNRLRWSSRYGLRRNIHIQAIPSSQLNSVTNESFHSASTTTNSAISPDAKFEVVGSPYSLLSVSLSASQNLYTRRGTLVGLSGKPENVVSTLRILEPFRRAALGIPFLYQKISSTSPVSALVSVKSPVTSFALLQLNGTVDWMLAQRNALLAWTGHSLTIKPRFNKQLSISHWGNSEVTGRGVIALVGKGQIYSITLKEGEQYIAHPSNVVAYTMMQTPPQPYRFKSTTIRFPVPNLGVGKRLFNTNFMSNLSKSDTWMAVMRIFHTFRTWTRRTIWGDRLFLQFQGPTTLLVQSRAARVNDILADHEVNEIADTTPGVTRAAVEATEVSPPEDVAHQTATKENHQRQSIATVHRDGKIDFKSTE
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EFTU2_YERPP
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGSARAFDQIDNAPEEKARGITINTSHVEYDTPARHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPVIRGSALKALEGDAEWEAKIIELAEALDSYIPQPERAIDRPFLLPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIIDTIKTTCTGVEMFRKLLDEGRAGENVGVLLRGTKRDDVQRGQVLAKPGSIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNVNMVVNLIAPIAMDDGLRFAIREGGRTVGAGVVAKVIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR8_LIRTU
Sequence: MGRDTIADILTSIRNADMDKKGTVRIASTNMAESVVKILLREGFIENVRKHRENNKYFLVSTLRHRRNRKGTYRNILKRISRPGLRIYSNYQRIPRILGGMGIVILSTSRGIMTDREARLEGIGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MGMT_BOVIN
Sequence: NPIPILTPC
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LHPL6_DANRE
Sequence: MASSLTCAGVIWALLSFLCAATSCVGFFMPYWLLGSQMGKPVSFGTFRRCSYPIRDEARGGTVMLEQCGRYASFQGIPSLEWRICTVVTGIGCGLLLLVALTAIMGCCVTDLISRTIGRVAGGIQFVGGLLIGSGCALYPLGWDSEEVRQTCSNSSDQFDLGSCEIGWAYYCTGAGAAAAMVLCTWMACFAGKKQKHYPY
What are the official names of this protein?
LHFPL tetraspan subfamily member 6 protein.
What is the protein family that this protein belongs to?
Belongs to the LHFP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MCP1_ECOLI
Sequence: MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVAELMESASISLKQAEKNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQDGFEKQYVAYMEQNDRLHDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRIQQQQRETSAVVKTVTPAAPRKMAVADSEENWETF
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.  Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.
What are the official names of this protein?
Methyl-accepting chemotaxis protein I, MCP-I, Serine chemoreceptor protein.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Found predominantly at cell poles.
Protein: RL11_HUMAN
Sequence: MAQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:32669547, PubMed:19191325).  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (PubMed:32669547, PubMed:19191325).  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (PubMed:32669547, PubMed:19191325).  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:32669547, PubMed:19191325).  As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs (PubMed:19061985, PubMed:12962325, PubMed:24120868).  It also couples ribosome biogenesis to p53/TP53 activation.  As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53 (PubMed:24120868).  Promotes nucleolar location of PML (By similarity).
What are the official names of this protein?
60S ribosomal protein L11, CLL-associated antigen KW-12, Large ribosomal subunit protein uL5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: YTJA_ECOBW
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TTCA_BORPE
Sequence: MTLTASPTAARTPAEEKARFEGNKLAKRLARETTRAIADYNMIEAGDKVMVCLSGGKDSYALLDILLSLQKRAPFAFEIIAVNLDQKQPGFPPEILPDYLRALGVPFHIETQDTYSIVTRVIPEGKTMCSLCSRLRRGILYRVASELGATKIALGHHRDDILGTFFLNLFYGGKAKGMPPKLVSDDGRHTVIRPLVYVPESDLIAYAQFKQFPIIPCNLCGSQENLKRKEVGRMIQEWDRKHPGRSWNVFNALSRVVPSHLMDRDLFDFVGLKPTGVADAGGDTAFDQIDPEPDTAGPGCASDAPAGQADGMAEQRVVFR
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHPD_SOLUE
Sequence: MELEQLLNSVPEYAKDLKLNMGGVLRQTELTEQQAWGTAVACAIAARNPQLRESVLGEAAKHLNEQALFAAKAAASVMGMNNIFYRFRHLSTNPKYGAMPARLRMQVIAKHGSDPIDFELWCLAVSAMNGCGVCVDSHENVLREKGVSEEAVLAAIRIASTIHGLAAILDVEADPIA
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: NEP1_SULTO
Sequence: MKINLILLDSSLELVPKEIASHPAVIRNARKRNKKPEHTILDISLHYHAMKNLPNWRKRGRPDIVHLALLMFLTEKVPIKGEVYIHTIDGKIIYVNSDMRPPKNYNRFIGLAEQLLLHGQVPINDANPLMKILNIKLTDLKSKYKIGVLSEDGKKVKPEELCNLGENWLLGVGAFPHGDFSEEIKGVADEYFSISNYKLETHQVICRIISACLQQLGWP
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: SOTB_HAEIN
Sequence: MSLYLKAEKIQSWRVLIMACAGFIFNTTEFVPVAMLSDIAQSFDMQTADTGLMMTVYAWTVLIMSLPAMLATGNMERKSLLIKLFIIFIVGHILSVIAWNFWILLLARMCIALAHSVFWSITASLVMRISPKHKKTQALGMLAIGTALATILGLPIGRIVGQLVGWRVTFGIIAVLALSIMFLIIRLLPNLPSKNAGSIASLPLLAKRPLLLWLYVTTAIVISAHFTAYTYIEPFMIDVGHLDPNFATAVLLVFGFSGIAASLLFNRLYRFAPTKFIVVSMSLLMFSLLLLLFSTKTIIAMFSLVFIWGIGISCIGLSLQMRVLKLAPDATDVATAIYSGIFNAGIGAGALFGNLATTYLGLNEIGYTGAALGLIGFIIFITTHLKYRHTFLLQNK
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL34_LEPIN
Sequence: MKRNYQPSRVKRARTHGFRARMATAGGRKVLSRRRKKGRYKLTVSDEKLGKKY
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.