PharMolix/UniProtQA huggingface dataset:
Protein: PELO_PYRNV
Sequence: MKYEIDAKRRTVRVVPEREEDLYFVYLLVERGDVVRGWTVREYKPEGAKEGERVKMYLAVRVESLEYHKFRGSLRIRGPVVEVQEGVEGVKGRRHTFDVVPGREIEIEKAAEFPLDVVEEILKMAQALMPKVLLVSIDDEEAAFAYITALGVELIQVVHNASKGEESLFDGYLESVRKQVDELSRRLKPDKLVVAGPAMLVEHIARYIRGDKAPQGSGGLAGVYEFIRSGLYDELKTQMGVKAYEKLIHMAATSRESVAIGPQEVEEAASLGRVDFVLVLDSYIKESPEKAWVLLSQIYKTKGRIYIVREDTEVGAGIRAMGGIAAVLRW
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_XANCB
Sequence: MAIRQLPEILINQIAAGEVVERPASVVKELVENALDAGATRVDIDLEEGGVRLIRIRDNGGGIAPEELPLAVSRHATSKIASLDDLETVATLGFRGEALPSIASVSRFTLASRRPDAEHGSALQIEGGRLGEVMPRAHAPGTTVEVRELFFNVPARRKFLRAERTELGHIEEWLRSLALARPDVELRVSHNGKPSRRYKPGDLYSDARLGETLGEDFARQALRVDHSGAGLRLHGWVAQPHYSRASTDQQYLYVNGRSVRDRSVAHAVKMAYGDVLFHGRQPAYVLFLELDPARVDVNVHPAKHEVRFREARLIHDFVYRTLQDALAQTRAGALPADVGVGGAAALGIGAVAAQGGGSYVADAGAGHPGAGSGSGYASWAPSQAPLGLRVDEARAAYAALYAPAAGSALRDDGQPVLSGTGLPATAHDSGVPPLGYAVAQLHGIYILAENAEGLIVVDMHAAHERIGYERLKQAHDSIGLHAQPLLVPMTLAVGEREADTAEREADTLASLGFEITRSGPQSLHVRSIPALLANADPEALLRDVLGDLREHGQSRRIATARDELLSTMACHGAVRANRRLTVPEMNALLRDMEATERSGQCNHGRPTWARFTLGEIDRWFLRGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: FSA_KLEP7
Sequence: MELYLDTANVAEVERLARIYPLAGVTTNPSIIAAGKVPVWDVLPRLQKAVGPEGTLFAQTMSRDAQGMVEEAKRLSNAVPGIVVKIPVTAEGLAAIKLLKKEGIPTLGTAVYSASQGLLAALAGAKYVAPYVNRVDAQGGDGIRMVQELQSLLEMHAPESKVLAASFKTPRQALDCLLAGCEAITLPLDVAQQMLGTPAVESAIEKFEQDWNNAFGALNL
What is the function of this protein?
Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
What are the official names of this protein?
Fructose-6-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTE1_PONAB
Sequence: MGIRGLMSFVEDHSNEFFTDLKLRDTKIVIDGYALFHRLCFSSNLDLRYGGDYDSFADVVQKFFESLFACNICPYVVLDGGCDISDKKLTTLKDRAREKIQMAHSLSVGGSGYVCPLLIREVFIQVLIKLRVCFVQCFSEADRDIMTLANHWNCPVLSSDSDFCIFDLKTGFCPLNSFQWRNMDTIKGTQNYIPAKCFSLDAFCHHFSNMNKALLPLFAVLCGNDHVNLPIMETFLSKARLPLGATSSKGRRHHRILGLLNWLSHFANPTEALDNVLKYLPKKDRENVKELLCCSMEEYQQSQVKLQDFFQCGTYVCPDALNLGLPEWVLVALAKGQLSPFISDALVLRRTILPTQVENMQQPNAHRISQPIRQIIYGLLLNASPHLDKTSWNALPPQPLAFSEVERINKNIRTSIIDAVELAKDHSDLSRLTELSLRRRQMLLLETLKVKQTILEPIPTSLKLPIAVSCYWLQHTETKAKLHHLQSLLLTMLVGPLIAIINSPGKEELQEDGAKMLYAEFQRVKAQTRLGTRLDLDTAHIFCQWQSCLQMGMYLNQLLPTPLPEPDLTRLYSGSLVHGLCQQLLASTSVESLLSICPEAKQLYEYLFNATRSYAPAEIFLPKGRSNSKKKRQKKQNTSCSKNRGRTTAHTKCWYEGNNRFGLLMVENLEEHSEASNIE
What is the function of this protein?
Possible role in EGF receptor signaling.
What are the official names of this protein?
Protein asteroid homolog 1.
What is the protein family that this protein belongs to?
Belongs to the asteroid family.
Protein: PDXK_ECOLC
Sequence: MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVVTSASGNEENQEMQVVVVTADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALTDAVHRAGLRVLEVMRYTQQHESDELILPPLAEA
What is the function of this protein?
B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i. e.  PNP, PLP and PMP.
What are the official names of this protein?
Pyridoxine/pyridoxal/pyridoxamine kinase, PN/PL/PM kinase, B6-vitamer kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxK subfamily.
Protein: TPH_RANTE
Sequence: MFTLKKSLLLLFFLGTINLSLCEEERNAEEERRDEPDERDVQVEKRLSPNLLKSLLGK
What is the function of this protein?
Antimicrobial peptide that renders both the outer and inner membrane of bacteria permeable to hydrophobic substances of low molecular mass.
What are the official names of this protein?
Temporin-1Th, TH, Temporin-H.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NCAP_CVBLY
Sequence: MSFTPGKQSSSRASSGNRSGNGILKWADQSDQSRNVQTRGRRAQPKQTATSQQPSGGNVVPYYSWFSGITQFQKGKEFEFAEGQGVPIAPGVPATEAKGYWYRHNRRSFKTADGNQRQLLPRWYFYYLGTGPHAKDQYGTDIDGVFWVASNQADVNTPADILDRDPSSDEAIPTRFPPGTVLPQGYYIEGSGRSAPNSRSTSRASSRASSAGSRSRADSGNRTPTSGVTPDMADQIASLVLAKLGKDATKPQQVTKQTAKEIRQKILNKPRQKRSPNKQCTVQQCFGKRGPNQNFGGGEMLKLGTSDPQFPILAELAPTAGAFFFGSRLELAKVQNLSGNLDEPQKDVYELRYNGAIRFDSTLSGFETIMKVLNENLNAYQQQDGMMNMSPKPQRQRGQKNGQGENDNISVAAPKSRVQQNKSRELTAEDISLLKKMDEPYTEDTSEI
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the betacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: BACA_MYCTU
Sequence: MGPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFVGPNSVRVWLMLGVLLLSVVLAVRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRGFWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHHLTQDWLDGRAYYRDLFIDETIDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLNIFGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAVGFYRGERVEGTQLQRRFTPVIDNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAGQIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIRLHGLVDANEKGRALPAVLTRPSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYASGTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDRLDEERDWAKVLSPGEQQRVAFARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDCIVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV
What is the function of this protein?
Multi-solute ABC transporter that mediates uptake of unrelated hydrophilic compounds (PubMed:32296172).  Can transport vitamin B12 and related corrinoids, and antimicrobial peptides such as bleomycin (PubMed:18996991, PubMed:32296172, PubMed:23407640).  Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation (PubMed:32296172).  Contributes to maintenance of chronic infections (PubMed:18996991).
What are the official names of this protein?
Hydrophilic compounds import ATP-binding/permease protein BacA, Hydrophilic compounds ABC transporter BacA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROA_RHOP5
Sequence: MTHSVQPTPLQARKSPALQGRVRVPGDKSISHRALILGALSVGETTITGLLEGEDVLNTAKAMQALGAKVERTGEFAWRVNGVGVGGFAQPDAALDFGNSGTGCRLVMGAVAGCPIAATFDGDASLRSRPMKRIVDPLQLMGASVIASAEGGKLPLTLQGAKNPLPIEYRTPVASAQIKSAVLLAGLSAPGVTTVIEQEASRDHTELMLQHFGAQIVSVPEGVHGRKISLTGQPELRGAPVVVPADPSSAAFPMVAALIVPGSDLVLTDVMTNPLRTGLFATLREMGASIEESELRDDAGEPMATFRVRASKLKGVTVPPERAPSMIDEYLVLAVAAAFAEGTTRMRGLQELRVKESDRLEATAAMLRVNGVDVAIEGDDLIVEGRGHVPGGGLVATHMDHRIAMSALVMGLASDQPVQVDDTAFIATSFPDFIPMMRRLGADFA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_COREF
Sequence: MAFFFRPEPKMVTPEEALKGGRHPVLESPQPHTVLGTPITGPWKEGQKRVWIGLGCFWGVEQMYWKMDGVESTSVGYAGGYTPNPTYREVCSGRTGHTEIVEVVYDPEKITLAELVARGLEAHDPTQGYRQGNDVGTQYRSAFYVETGEEAETVRQIVSTYGETLKSHGFGEITTEVDVITPADYYLAEDYHQQYLHKNPDGYCPHHSTGIPCGVEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: SAM14_MOUSE
Sequence: MASSKLREPVDEVFDLDLAVPETTRLDSSLHKARAQLLAKGRRHRPSRSRLRDSASSAEDGEGSDGPGGKVTDGCGSPLHRLRSPLHSGPGSPASGSFCLEPPGLRRSLDEDEPPPSPLARYRPLHNAASHEGLAATSGSPPRSAPSSDSSPSFVRRYPRAEPHSEDDSRDASPPEPASPTIGLDKKTRRKFLDLGVTLRRASTSRSRKEKGSNRLSMGSRESVEGSGRTGSSPFLPFSWFTDSGKGSASSGSTTSPTCSPKHEGFSPKKSASQESTLSDDSTPPSSSPKIPGGPRQETKCSYPYHTLSQSSDEFLDESLPAVQHWTSQQVGQWLHSLNLEQYAAEFAARQVDGPQLLQLDGSKLKSLGLSNSHDRALVKRKLKELAAAAEKERKAQEKTAKQREKLRRRENDAKKS
What are the official names of this protein?
Sterile alpha motif domain-containing protein 14, SAM domain-containing protein 14.
Protein: HRCA_MYCUA
Sequence: MGTADERRFEVLRAIVADFVATHEPIGSKSLVERHNLGVSSATIRNDMAVLEAEGYIAQPHTSSGRVPTEKGYREFVDRLDDVKPLSMVERRAIQGFLESGVDLDDVLRRAVRLLAQLTRQVAVVQYPTLSTSKVRHLEVIALTPARLLVVVITDSGRVDQRIVELGDVIDDHQLSQLRELLGQALEGKKLAAASVAVADFAGQLSGAGGLGDAVGRSATVLLESLVEHTEERLLMGGTANLTRNAADFGGSLRSILEALEEQIVVLRLLAAQQEAGKVTVRIGHETEAEQIVGTSMVSTAYGSNDTVYGGMGVLGPTRMDYPGTIASVAAVALYIGEVLGAR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: S27A3_HUMAN
Sequence: MAALLLLPLLLLLPLLLLKLHLWPQLRWLPADLAFAVRALCCKRALRARALAAAAADPEGPEGGCSLAWRLAELAQQRAAHTFLIHGSRRFSYSEAERESNRAARAFLRALGWDWGPDGGDSGEGSAGEGERAAPGAGDAAAGSGAEFAGGDGAARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARALVLAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKILQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCMGIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERGHKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDLMQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPSTLSDPLYVLDQAVGAYLPLTTARYSALLAGNLRI
What is the function of this protein?
Mainly functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (PubMed:23936004).  Can mediate the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across membranes (By similarity).
What are the official names of this protein?
Long-chain fatty acid transport protein 3, FATP-3, Fatty acid transport protein 3, Arachidonate--CoA ligase, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 3, Very long-chain acyl-CoA synthetase homolog 3, VLCS-3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: NDK_PSEPF
Sequence: MAVQRTFSIIKPDAVAKNVIGKITTRFEDAGLRVVASKLKQLSKAEAEGFYAEHSARGFFGELVAFMTSGPVVVQVLEGENAIARNRELMGATNPKEAAPGTIRADFAESIDANAVHGSDSEAAAAREIAYFFAATEVTTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK14_BRADI
Sequence: MIQPQTLLNVADNSGARKLMCIRVIGTAGNQRYARIGDVIVAVIKDAVPQMPLERSEVIRAVIVRTCKEFKCEDGIIIRYDDNAAVIIDQKGNPKGTRVFGAITEELRELNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y231_BARHE
Sequence: MRDMMNMMKKAKEMQEKMQKIQEEMANLQVTGTAGGGLVSITLNGKNTITAIKIDPSLLKPEEIEILEDLIMAAYNEAKTKIEIAMQEKTKSMTAGLPLPPDFKLPFS
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BH02310.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYY_STRPM
Sequence: MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIKGQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIETGISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMTVPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLFLDEIAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANELKQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQLSNDDKIDDQLTVIRRGKKKYAVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_VIBPA
Sequence: MTTEKINLLDFDRKGMRQFFAEELGEKAFRADQVMKWIYHFGVDDFDNMTNINKKLREKLQHKCEIKAPTVAEAQHSSDGTIKWAMKVGDQDVETVYIPEEDRATLCVSSQVGCALECKFCSTAQQGFNRNLKVSEIIGQVWRAAREIGLQKETGRRPITNVVMMGMGEPLLNMKNLIPALEIMLDDLGFGLSKRRVTVSTSGVVSGLDQMTGKIDVALAISLHAPNDKLRSEIMPINDRWDIQDFLASVRRYIASSNANRGKVTVEYVLLDHVNDDMGHARELAELMKDTPCKINLIPFNPYPGSPYKKPSNSRIDRFQKTLMQYEHTVTVRKTRGDDIDAACGQLVGDVIDRTKRTAALKAARGAETIDVKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCYD_SALA4
Sequence: MPLHHLTRFPRLELIGAPTPLEYLPRLSDYLGREIYIKRDDVTPIAMGGNKLRKLEFLVADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPDAQLQTLATRIEAQGFRPYVIPVGGSSALGAMGYVESALEIAQQCEEVVGLSSVVVASGSAGTHAGLAVGLEHLMPDVELIGVTVSRSVAEQKPKVIALQQAIAGQLALTATADIHLWDDYFAPGYGVPNDAGMEAVKLLASLEGVLLDPVYTGKAMAGLIDGISQKRFNDDGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: UREG_STAA2
Sequence: MANPIKIGIGGPVGAGKTQLIEKVVKRLSKEMSIGVITNDIYTKEDEKILVNSGVLPESRIIGVETGGCPHTAIREDASMNFAAIDELLERHDDIELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASLEQMAEDTKVFRGKRPFTFTNLKTDEGLDEVIDWIERDTLLKGLS
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCN2_RAT
Sequence: MAAATAAAATVAGEGMEPRALQYEQTLMYGRYTQELGAFAKEEAARIRLGGPEPWKGSPSARATPELLEYGQSRCARCRICSVRCHKFLVSRVGEDWIFLVLLGLLMALVSWAMDYAIAVCLQAQQWMSRGLNTNILLQYLAWVTYPVVLITFSAGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFVAKVIGLTCALGSGMPLGKEGPFVHIASMCAALLSKFLSLFGGIYENESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDFPFDLQELPAFAVIGIASGFGGALFVYLNRKIVQVMRKQKTINRFLMKKRLLFPALVTLLISTLTFPPGFGQFMAGQLSQKETLVTLFDNRTWVRQGLVEDLGAPSTSQAWSPPRANVFLTLVIFILMKFWMSALATTIPVPCGAFMPVFVIGAAFGRLVGESMAAWFPDGIHTDSSTYRIVPGGYAVVGAAALAGAVTHTVSTAVIVFELTGQIAHILPVMIAVILANAVAQSLQPSLYDSIIRIKKLPYLPELGWGRHQQYRVRVEDIMVRDVPHVALSCTFRDLRLALHRTKGRMLALVESPESMILLGSIERSQVVALLGAQLSPARRRQHMQKLRKAQMSPPSDQESPPSSETSIRFQVNTEDSGFPGAHGQTHKPLKPALKRGPSNATSLQEGTTGNMESAGIALRSLFCGSPPLESTTSELEKSESCDKRKLKRVRISLASDSDLEGKMSPEEILEWEEQQLDEPVNFSDCKIDPAPFQLVERTSLHKTHTIFSLLGVDHAYVTSIGRLIGIVTLKELRKAIEGSVTAQGVKVRPPLASFRDSATSSSDTETTEVHALWGPRSRHGLPREGTPSDSDDKCQ
What is the function of this protein?
Voltage-gated chloride channel (PubMed:1311421, PubMed:12163466).  Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport (PubMed:1311421).  Involved in the regulation of aldosterone production.  The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage-gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (By similarity).
What are the official names of this protein?
Chloride channel protein 2, ClC-2.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
Protein: GPMA_BORRA
Sequence: MYKLVLVRHGESKWNKENLFTGWTDVKLSEKGVSEACEGGRILKEEGYSFDIAFSSMLVRANDTLNIILCELGQSYIDVEKSWRLNERHYGALQGLNKAETAEKYGEDKVLIWRRSYNVPPMPLDESDKRHPIHDSRYKNIPKSELPSTECLKDTVARVIPYWTDKIAKAILEGKRVIVAAHGNSLRALVKYLDNMSEEDILKLNIPTGIPLVYELDKNLKPVKHYYLGDEDKIKAAMESVANQGKKIDR
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: DPO43_RHILO
Sequence: MVPERGADPRKIIHVDMDAFYASVEQRDNPELRGKPLAVGGAAARGVVAAASYEARAFGVRSAMPSVTAKRKCPELIFVPPRFDVYRAVSAQIRDVFAEHTDLIEPLSLDEAYLDVTQNRLNISSATTIAEMIRAKILEVTGLTASAGISYNKFLAKMASDQNKPNGQFVITPRHGPAFVETLPVNKFHGVGPATAAKMEALGIETGADLKERSLSFLQQHFGKSGLWYYQIARAIDERAVDPDRPRKSIGAEDTFAADIVDLETSLAELKPLVAKVWGYCEGKGIRGRTVTLKIKFADFQQITRSRTVAVPIELSDFEHLAADLLGSVFPVRKGIRLLGVTLSSLGDVLPPDQRQLRFEL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (By similarity).
What are the official names of this protein?
DNA polymerase IV 3, Pol IV 3.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_CHRSD
Sequence: MWLSLVAIGAGAALGANLRWLLGMWLNALFPALPPGTLAANWLGAWLIGIAIALFAQLPQLSPEWRLFVVTGFLGALTTFSTFSAEMFGNLQAGRYAMALTGIAVHVAGSLAMTGLGIATFGALKQLGGIIK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRH_STAS1
Sequence: MAQTSKYERVVLKLSGEALAGDDGFGINPIIIKSIAEQVAEVAKLDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLECDTRVLTSIEMKQVAEPYIRRRAIRHLEKNRVVIFAAGIGNPYFSTDTTAALRAAEVEADVILMGKNNVDGVYSADPKVDPNAIKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLNVFSITEEGNIKRAVMGEKIGTLITK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATB_PSYCK
Sequence: MFDIGFSELLLFGVIALIVLGPEKLPQAARTAGQWYAKIRRTVSTLQSEIEAELDLAETRQQMQKELAKIRQTEAEMRREMAEMRGSMQEFESSKNQHLKASRDLVDDAKPRQSSQGSSENDDNRPVSPKSFDYAYDNNRQAEKPESSEQPSAQGDNDSLKTDFNDNANPVIQTITTRPWENMWFRLGAYDKARRLPQPPYLPNYKADILLNSHIDSLLPKQASVNEQESH
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YCF3_PINTH
Sequence: MPRSQRNDNFIDKTFTIVADILLRIIPMAPGEKEAFTYYRDGMSAQSEGEYAEALQNYYEAMRLETDPYDRSYILYNIGLVHTSNGEHTKALEYYFQALERNPSLPQALNNTALICHYRGEQAIRQGDPETAEAWFDQAAEYWEQAIALAPGNYIEAQNWLKITGRFGE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.