PharMolix/UniProtQA huggingface dataset:
Protein: CYB_FARAB
Sequence: MPNQHMLLLSNLLPVGLNISTWWNFGSMLLTCLALQITTGFFLAIHYTANINLAFSSIIHITRDVPHGWIMQNLHATGASMFFICIYIHIARGLYYGSYLNKGVWLSGTILLITLMATAFFGYVLPWGQMSFWAATVITNLLTAVPYLGTPLTTWLWGGFSINDPTLTRFFALHLILPFAIISLSSIHIILLHNEGSSNPLGXNSDIDKIPFHPYHSHKDALMLTILITLLFIILSFTPNIFNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGTLALILSVTILLTVPFTHTSYVRSMTFRPLAQLMFWTLIATFMTITWAATKPVEPPFTIIGQTTSILYFSFFIINPLLGWLENKIMITH
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: C7A68_MEDTR
Sequence: MELSWETKSAIILITVTFGLVYAWRVLNWMWLKPKKIEKLLREQGLQGNPYRLLLGDAKDYFVMQKKVQSKPMNLSDDIAPRVAPYIHHAVQTHGKKSFIWFGMKPWVILNEPEQIREVFNKMSEFPKVQYKFMKLITRGLVKLEGEKWSKHRRIINPAFHMEKLKIMTPTFLKSCNDLISNWEKMLSSNGSCEMDVWPSLQSLTSDVIARSSFGSSYEEGRKVFQLQIEQGELIMKNLMKSLIPLWRFLPTADHRKINENEKQIETTLKNIINKREKAIKAGEATENDLLGLLLESNHREIKEHGNVKNMGLSLEEVVGECRLFHVAGQETTSDLLVWTMVLLSRYPDWQERARKEVLEIFGNEKPDFDGLNKLKIMAMILYEVLRLYPPVTGVARKVENDIKLGDLTLYAGMEVYMPIVLIHHDCELWGDDAKIFNPERFSGGISKATNGRFSYFPFGAGPRICIGQNFSLLEAKMAMALILKNFSFELSQTYAHAPSVVLSVQPQHGAHVILRKIKT
What is the function of this protein?
Catalyzes the carboxylation of oleanolic acid at the C-23 position to form gypsogenic acid.  Involved in the hemolytic saponin biosynthetic pathway.
What are the official names of this protein?
Cytochrome P450 72A68.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EFG_MYCPU
Sequence: MSREYDLKDYRNIGIMAHIDAGKTTTTERILFHTGKIHKIGETHDGGSQMDFMAQEKERGITITSAATTAFWRGKRINIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATNYKVPRIVFVNKMDKAGANLEESIKSVKTRLNGNAVAIQLNMGSESDYRGHIDLVEMKAWEFDGKPEENGKEIEIPAEYLEAAQIERSKLIEAVSSFDDEVMMLALEEQEIPVDLLKSAIRKATLTSEFFPVVCGTAFKNKGVKAMIDAVVDYLPSPLDVPAIKGYFQEKEVLVTASDENDFSALAFKIMNDPFVGSLTFFRVYSGILSKGSYVYNTTKDKKERIGRILQMHANSREEIDEVRTGDIAAAVGLKDTTTGDTIVGDKSKHIILEKMVFPEPVISQALEPESKAATEKLSLGLQKLAAEDPTFRTFTDTETGQTIIAGMGELHLDIIVDRLRREFGVQVKVGAPQVSYRETITAKADVEGKYIKQSGGKGQYGHVWITFEPNPNNGFEFVDKIVGGKIPKEYIKTIQKGLEEKMASGILAGYPMIDLKATLFDGSYHEVDSSEMAYKIAASMALTKAKDVVKTVLLEPIMDVSVVFPKEYYGDVVGDLSRRRGQIINDETRSDGASVIKSHVPLSEMFGYATDLRSMTKGRGTYQMHFDHYERTPRNIADEIIKKRNIKN
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCDB_LEPBP
Sequence: MILTGKEILKRLGSDIKIEPYDEKLLNPNSYNLRLHEDLLVYSEFPLDMKKPNPVRTLKIPEEGLLLEPGNLYLGRTIEFTETHNLVPMLEGRSSIGRLGMFVHITAGFGDVGFKGFWTLEIQVTHPLRVYSGVQICQIFYHTVEGEISEYKSGKYQANQGIQPSLLYKDFEKK
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: HMUV_BORPE
Sequence: MTLQARNLTLARGGAPILTDVSLTLAPGALVGLLGANGAGKSTLLAALAGELAPRSGQVFLGDADLATLSARQLARRRAVLPQKPSLSFDLGVSDVVGMGAYPFPELDPAAVRQLVRDALEQAGVTHLAQRRYPQLSGGEQQRVQFARVLAQCHAMHAPGQTRYLMLDEPISNLDPRHQMELLATARALAHEAGMGVLVIVHDINQAARWCDTLALLADGRLAALGPPADVLTPDHMRRVYGIEADVLAHPTLPGRLLVLAR
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YL153_MIMIV
Sequence: MNNSMILLMVIASFVAGYLSTMNLWANSIGDIRLHLNDFYMVLLMVGWMIVMCYILMKSHMGITKTQLIITITIIIIIVYAIRTQAFIDDKQYLNGMIPHHSMAITMSKWIVNRTKDPRIKQLATDIIISQQNEINEMNSILDERKLQNKVF
What are the official names of this protein?
Uncharacterized protein L153.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y698_NEIM0
Sequence: MKIVLISGLSGSGKSVALRQMEDSGYFCVDNLPLEMLPALVSYHIERADETELAVSVDVRSGIDIGQAREQIAYLRGLGHRVEVLFVEAEESVLVRRFSETRRGHPLSNQDMTLLESLKKEREWLFPLKEIAYCIDTSKMNAQQLRHAVRQWLKVERTGLLVILESFGFKYGVPNNADFMFDMRSLPNPYYDPELRPYTGMDKPVWDYLDGQPLVQEMVDDIEKFLTHWLPRLEDESRSYVTVAIGCTGGQHRSVYVVEKLARRLKGRYELLIRHRQAQNLPSR
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein NMCC_0698.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: NUOCD_YERPG
Sequence: MTDLTTSDSLQPAWQTRDHLDDPVIGELSNRFGPEAFVVQATRTGMPVVWVKREQLLEVMSFLRKQPKPYVMLFDLHGVDERLRTHSQGLPDADFSVFYHLLSIERNRDIMLKVALSEKDLHVSTATKIFPNANWYERETWEMFGITFDGHPHLTRIMMPQSWEGHPLRKDYPARATEFDPYVLTKQKEDLEMESLTFKPEDWGMKRGTENEDFMFLNLGPNHPSSHGAFRIVLQLDGEEIIDCVPDVGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIVVPDRVNTIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKVYDVIEAITGFRMHPAWFRIGGVAHDLPRGWERLLRDFLDWMPKRLDSYVKAALQNSILKGRSVGVAAYNAKEALEWGVTGAGLRATGVEFDVRKWRPYSGYENFDFEVPVGNNGDCYDRVMLKVEELRQSLRILEQCYKNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPSVIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FLIJ_ECOLI
Sequence: MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAGITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE
What is the function of this protein?
The FliJ protein is a flagellar protein that affects chemotactic events.  Mutations in FliJ results in failure to respond to chemotactic stimuli.
What are the official names of this protein?
Flagellar FliJ protein.
What is the protein family that this protein belongs to?
Belongs to the FliJ family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CSP1_STREE
Sequence: MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK
What is the function of this protein?
Acts as a pheromone, induces cells to develop competence for genetic transformation.
What are the official names of this protein?
Competence-stimulating peptide type 1, CSP-1.
What is the protein family that this protein belongs to?
Belongs to the ComC family.
What are the subcellular locations of this protein?
Secreted.
Protein: COFD_METMP
Sequence: MKITILSGGTGTPKLIQGFKEILPNEDISVIVNTGEDTYIGDIYLSPDIDTVLYTFSNLINDETWYGLKGDTFFCHEQLKNFGFDEVLRIGDKDRALKMHKTSLLKKGVPMSEIVDIERKSLSINSKIYPMSDEKIESKVLIEENNEKILLKFHDFWVSRRGNAKVLDIFYENSNYAKAADGVLKAIEESDFVIIGPSNPITSIGPILSISEIKDALKEKLVFAVSPIVGENPVSGPAGTLMHAKGYPVNAVGVYEYYKDIVDVLVLDNSDINKKKEMNCEVLYANTIMKTIDDKITLARNILDYYKSR
What is the function of this protein?
Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
What are the official names of this protein?
2-phospho-L-lactate transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: NSP_MYMVV
Sequence: MFNRNYRTPLKLRHSNFGFRWQPMTPSRGRLRHNKPSASRKLSYDRVEREMRTNSIVEVQHGSHMSLEKNTDVSSFVQYPARGINGDGRCRDYIKLLKLDVSGVINIKSSNGDQDMEPGDKLSGLFILTVLLDKKPYLPEGVNKLPSFAELFGPYSAAYANMHLLDSQKPRFKVLGTIKKFVNCTPGTLYGPLKLNMPLSRRKCPLWTTFKDPDQGNCGGNYKNISKNAIVLSYAFISMHSLIVEPYFQFELKYVG
What is the function of this protein?
Binds to the genomic viral ssDNA, shuttles it into and out of the cell nucleus.  Begomoviruses use 2 proteins to transport their DNA from cell to cell.  The nuclear shuttle protein (NSP) shuttles it between nucleus and cytoplasm and the movement protein (MP) probably transports the DNA-NSP complex to the cell periphery and facilitates movement across the cell wall (By similarity).
What are the official names of this protein?
Nuclear shuttle protein, NSP, Protein BR1, Protein BV1.
What is the protein family that this protein belongs to?
Belongs to the begomovirus nuclear shuttle protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocated to the plasma membrane by the movement protein BC1.
Protein: SUB2_ARTBE
Sequence: MQLLNFGLLLLPFVAGDLAPQPEPLLAGPSDVVPGQYIVTLKEGLTSAQIRDHKKWVSSVHRANLDSFAAGASGVETEGIMKHFHIHDLNMYSGGFDEKTVEDLSRNPYVKSVHPDQHVYLAKTVTQRQARWGLGYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHVEFEGRGILGHNAIPNKPHTDEFGHGTYVAGIIAGKTYGVAKKANVVSAKAFDTGSSTYNYILETYDWIVRNITDSNRKNKAVINLSISGAKYQPFDDAVEKAFKAGITTVVAAGNDGKDAKNNTPASSPNAITVGAVRWENTRPSFSNYGKLVDIWAPGELIKSCWKGGNNATSTQSGTSAASPHVAGLVAYLMSIENLPSPSAVTARVLNLTIPNLVKDAKDSPNRVAYNGIQERKFKLPK
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCH1_GEOKA
Sequence: MPEINFAQIEYAVRLILEAIGEDPNREGLVDTPKRVAKMYAEVFAGLQEDPKQHFQTVFSEEHEELVLVKDIPFYSMCEHHLVPFFGAAHVAYIPREGKVTGLSKLARAVEAVARRPQLQERITATIADSIVEALEPHGVMVVVEAEHMCMTMRGVKKPGSKTVTTAVRGVFETDANARAEVLSLIKA
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RTCA_METMA
Sequence: MIEIDGSYGEGGGQLVRTAVALSAVTGEEIKVTNIRENRPNPGLKQQHLKALETAAKICGARVSGLSQGSSELFFAPVEIKGGKYNIDIGTAGSITLLLQCIMPALPFVEEKVELTIRGGTDVAWSPTIDYLKHVTLRALEQFGYAGSVTLKERGYYPRGGGSVSAVFEPCKLHGFHFRKTEGNKKTESNPVGEGLKGEKSMMEEIIGVSHASNLPAHVPARQAESARSLFLEAGYDARIDVSSSEFFSTGSGITLWKGYCGGSALGKKGLPAEKVGRQAAEEVIKELRAGAAVDIHLADQLIPYMALAGNSSFTVRELTLHAATNIWVTEQFLDVKFKIKEKEGLFEVSVG
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOT1B_MOUSE
Sequence: MISLTDTQKIGMGLTGFGVFFLFFGMILFFDKALLAIGNVLFVAGLAFVIGLERTFRFFFQRHKVKATGFFLGGVFVVLIGWPLIGMIFEIYGFFLLFRGFFPVVVGFIRRVPVLGSLLNLPGIRSFVDKVGESNNMV
What is the function of this protein?
May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
What are the official names of this protein?
Vesicle transport protein GOT1B, Golgi transport 1 homolog B.
What is the protein family that this protein belongs to?
Belongs to the GOT1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: TSN33_DANRE
Sequence: MGNAKRATQNDEDYTFVSPVVKYLLFFFNMIFWIISLVLISIGVYSRIVKHETALACLTVDPALILMVVGILMFFITFCGCVGSLRENICLLQTFCIFLTIMFLLQLLAGVLGFVFSDKARGKVTDMFDNAIKHYRDDLDLQNLIDYGQKQFNCCGGISFMDWSKNMYFNCSDDNPSRERCSVPFSCCLHAKEETIINTMCGHGMQALNYLAASAFINTNGCIDILVNWIHSNLFLLGGIALGLTIPQLVGILLSQVLINQIQDQIKLQNYNQQHRSDPWS
What are the official names of this protein?
Tetraspanin-33, Tspan-33.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYS_MYCMM
Sequence: MIDLKLLREDPDVVRRSQLSRGEDPALVDALLTADTARRTAISTADSLRAEQKAASKGVGGASPEERPALLQRAKDLAEQVKAAEATQSETEAAFTAAHMAIPNVILDGVPAGGEDDYAVLEVVGEPRAIDNPKDHLELGESLGLIDMARGAKVAGSRFYFLTGQGALLQLGLLQLALRLAVDNGFIPMIPPVLVRPEVMAGTGFLGAHADEVYRLEADDLYLVGTSEVPMAGYHADEIVDLSEGPLRYAGWSSCFRREAGSYGKDTRGIIRVHQFDKVEGFVYCTPADAEAEHQRLLAWQREMLAQIEVPYRVIDVAAGDLGASAARKFDCEAWVPTQGTYRELTSTSNCTTFQARRLATRYRDANGKPQIAATLNGTLGTTRWLVSILENHQQPDGSVRVPAALVGFVGTEVLEPKG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_SHESM
Sequence: MVTIRLARGGAKKRPFYNIVVADSRNARDGRFIERVGFFNPLARGQEETLRLDLARVEHWVSNGAATTDRVAKLIKDAKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: FTHS_LACJO
Sequence: MKSDIEIAQDTKELPITEIAKKVDLQPDEIELYGNDKAKISWKGINRIKQGKKLGKLILVTSISPTPAGEGKSTITIGLGDAISNQLHKNTLIALREPSMGPVFGLKGGATGGGYAQIITMEDINLHFTGDMHALTSAIDTLAALVDNYIYQDNSLELDPNRILLKRGIDVNDRTLRKITIGQGSRFNGIEHEASFAITVANELMAILCLATDIDDLKKRIGNMLVGFSVKDEPVYVKDLGFEGAIAALLSTALKPNLVQTLEHTPAIVHGGPFANIAHGANSVIATNTALHLSDYVLTEAGFGADLGGQKFMDFVSNHLDKRPDAVVVVATVRALKYQAEETTDHLDEENIPALEKGFENLKRHMENMAHYGVPVIVLINKFASDTEQELSKLKELVKADGFECEVVSYHDEGSKGGIKAAEKVVELTNKASDFTSVYEPTDSVEEKISKIAHNIYHAKDIEYSDKAKDQLAEIKKMGKDNLPVIMAKTQYSFTDKKSILGAPKDFTLHVKNLALKNGAGFIVVATGSILDMPGLPKYPAALDIDVDNNGKISGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: ABC3G_LAGLA
Sequence: MKPQTRNTVVRMDPDTFFYNFYNRPILSHRNTVWLCYEVKMKTNDPSRPPLVANIFQGQVSFNPEHHAEMYFLSWFRGNLLPACKRSQITWFVSWNPCLYCVAKVAEFLAEHPKVTLTVSTARLYCYRKKDWRRALRKLSQTGARVKIMDYEEFQHCWDNFVDNQREPFEPWNALPKHYTLLRITLGEVLRHRMDPVTFTYNFTNDPSVLGQHQSYLCYKVEHLRNGTWVPLHQHRGFILNEASNSVSFPEGRHAELCLLDLISFWKLKQAQRYRVTCFISWSPCFSCAEKVAEFLQENPHVNLHISAARIYDYQRGYKKGLRRLDRAGTPISMMKYSEFKHCWDTFVDHQGHPFQPWEELNEHSQALSGRLQAILQNQGN
What is the function of this protein?
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility.  After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA.  The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells.  Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA (By similarity).
What are the official names of this protein?
DNA dC->dU-editing enzyme APOBEC-3G, Deoxycytidine deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Mainly cytoplasmic, small amount are found in the nucleus.
Protein: CAI_PHAVU
Sequence: HEDNAGIAVYWGQDAREGDLVTACN
What is the function of this protein?
Alpha-amylase inhibitor, active against Z. subfasciatus alpha-amylase (ZSA) but not porcine pancreatic alpha-amylase (PPA).  Has chitinase activity.
What are the official names of this protein?
Chitinolytic alpha-amylase inhibitor PvCAI.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
Protein: UXAC_SHIB3
Sequence: MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTGLTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: MET_EULMM
Sequence: MKASAVLAPGILALLFTLVQGNDGECQEALAKSEMNVNMKYQLPNFTAETPIQNVVLHEHHIYLGATNYIYVLNDKDLQKVSEYKTGPVLEHPECFPCQNCSNNANLSSGIWKDNINMALLVDRYYDDQLISCGSVNRGACQRHILPPDNPADIQSKVHCMFSPQADEEPSQCPDCVVSALGAKVLLSEKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQKETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSTREEVFNILQAAYVSKPGAQLAKQIGASLNDDILFGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIVNKNNVRCLQHFYGPHHEHCFNRTLLRNSSGCEVRRDEYRTEFTTAFQRVDLFMGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSSTPHVNFQLDSHPVSPEVIVEHPLNQNGYTLVVTGKKITKIPLNGLGCGHFQSCSQCLFAPSFVQCGWCHDKCVRSEECPSGIWTQEICLPAIHKVFPTSAPLEGGTMLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTTNMLKCTVGPAMNEHFNMSIIISHGRGTAQYSTFSYVDPVITSISPSYGPKAGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQIISTEFPVKLKIDLANRETSSFSYREDPIVHEIHPTKSFVSGGSTITGVGKNLNSVSVPRMVINVQEAGRNFTVACQHRSNSEIICCTTPSLQQLNLRLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSHSEAVLCTVPNDLLKLNSELNIEWKQAVSSTVLGKVIVQPDQNFTGLIVGVVSISIILLLLLGLFLWMKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVNGEVDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GSA_BURCJ
Sequence: MSNNQILFERAQKTIPGGVNSPVRAFRSVGGTPRFVARAQGPYFWDADGKQYIDYIGSWGPMIVGHVHPEVLSAVQNVLADGFSFGAPTEAEIEIAEEICKLVPSIEQVRMVSSGTEATMSALRLARGFTGRSRIVKFEGCYHGHADSLLVKAGSGLLTFGNPTSAGVPADIAKHTTVLEYNNVAALEEAFGAFGDEIAAVIVEPVAGNMNLVRGTPEFLNALRALCTKHGAVLIFDEVMCGFRVALGGAQAYYGIAADLTCLGKVIGGGMPAAAFGGRRDIMAHLAPLGGVYQAGTLSGNPIAVAAGLKTLQLIQAPGFYDALTAQTKRLTDGLAAEARAAGVPFAADSIGAMFGLYFAERVPTSFAEVTKSDIARFNRFFHLMLDEGVYFAPSAYEAGFVSSTHDDAVIDATLAAARRAFAALAA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DABA_VIBCH
Sequence: MARAINSAYRSFINSSATDDRRTRMNAPRSLSALSTTANPALSTLVEQVCALIAPNWPLDRMIAVSPYWKRIDKPFAQAAAELKQLAASPMTMTLSDYHLRWQNKQIQSADLQQAIAEQNSDLSESTLIAALQQPTAPSHPWPLLCDTVDSRRDLEHHPAWNDAITHQISQFCAAYFDHHQADWSPDQQTGLFATWREAMIHDRSITLLLNETSVKQKATKLPEDAMAAIEQTLAQLAIAPAQQETYLQAVLMRISGWASWCAYLAWQAGFEGRHDEHLRDLLAIRLCWENLLDDGERGMGSVWLQWQQSWAPRQSCEEDRALRIALLWQRSAEIAYQRQLFAALTSAQESAPQSSYPEVQAAFCIDVRSEVIRRHLEAQSPHIQTLGFAGFFGLPIRYQLLGTEASRPQLPGLLAPSLIVSDSTGNEDQDAKLALRRRARLKRHFSWRAFHHLPASTFTLVETTGLAYLTKLLKRTLSYPALSASVERFAFTEHEWQSVKPQFTRDPQTLAQRAQMAANILRALGIATEQARLVLLVGHGSQTQNNPQRAGLDCGACCGQSGEVNARTLAALLNDQAVRQALPEYGISLRDDVHFIAALHNTTTEAMRLFDRHEIPTSHREALEQLDQQLTAASHGARQERAPSLELNHNHQAPPSKDNALSAQQLEQAFLRRAHDWAQTRPEWGLTNNAAFIIAPRQRSKQAKLDGRVFLHEYQPERDPEGQLLTQIMTAPMLVTHWINMQYFASTVDNRRFGSGNKTLHNVVGGNIGLFEGNGGDLRCGLALQSLHDGQGWRHEALRLTVVIDAPRERIEQVMASHRVVEHLVKHEWLYLARFADQGIEIYLQGTWQRITQPSSDSSAR
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.