PharMolix/UniProtQA huggingface dataset:
Protein: MUG_ECO5E
Sequence: MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQAGFTDHQLKPQEAQHLLDYRCGVTKLVDRPTVQANEISKQELHAGGRKLIEKIEDYQPQALAILGKQAYEQGFSQRGAQWGKQTLSIGSTQIWVLPNPSGLSRVSLEKLVEAYRELDQALVVRGR
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_CHLT3
Sequence: MTVDEVKGQVYDIIVTKMGVGKEQIKDDSKFTDDLGADSLDTVELIMEFENKFGIQIPDEDAEKISNVQDAINYIVEKKK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSRR_SHIBS
Sequence: MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: HCHA_PSEAE
Sequence: MSNERDTSRTPTPDPAEHNAFFPSPYSLSQYTSAKTDFDGADYPTPYKGGKKVLMIGTDERYILMQNASMFSTGNHPVEMLLPMYHLDKAGFEFDVATLSGNPVKLEMWAMPGEDEAVKSIYAKYLPKLKAPRKLADLLEQAVADDSPYAAVFVPGGHGVLAGIPHSREVKRLLNAFLAKDRYIITLCHGPACLLAPAVEEKPEDYPFKGYEICVFPDALDTGANLEIGYMPGPLPWLVGENLQKLGVKILNKGITGQVHRDRKLLTGDSPLASNNLGKLAAKTLLEAFAR
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEEX_SALEP
Sequence: METTKPSFQDVLEFVRLFRRKNKLQREIQDIEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKSDYEDRVDDYIIKNAEISKERRDISKKLKAMGEMKHADVKAE
What are the official names of this protein?
UPF0265 protein YeeX.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: RIBB_ECO7I
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: Y1125_METJA
Sequence: MMVKNTIDVKEILRELDTTRIKDYPLMSGKEILLRTNFKGCCGMPSQISQLNLKEQLESC
What are the official names of this protein?
Uncharacterized protein MJ1125.
Protein: ISPD_YERPP
Sequence: MSNFAVSLPEVIAVLPAAGIGSRMLVDCPKQYLTVGGKTIIEHAIFSLLHHPRIQRVIVVIHPQDTQFSRLSVAQDPRISTVYGGDQRANSVMAGLQLAGQAEWVLVHDAARPCLHLDDLSRLLSITECSQVGGILAAPVRDTMKRAEPGIQAIAHTVDRQDLWHALTPQLFPLELLKLCLSRALREGVAVTDEASALEHCGYHPILVTGRSDNIKVTRPEDLALAEFYLTQRQSLNNDSL
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RS5_ALIFM
Sequence: MAKEQQQATDLNEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKSMEKARRNMFTIALNEGTLHHAVKGRHTGSKVYMQPAAEGTGIIAGGAMRAVLEVVGVRNVLAKAYGSTNPINVVRATIAGLSSVKSPEMVAAKRGLTVESISE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SYFA_PSEPW
Sequence: MENLDALVSQALEAVERAEDINALEQIRVQYLGKKGELTQVMKTLGNLPAEERPKVGALINDAKERVTEVLNARKAAFEEAELSARLAAECIDVTLPGRGQATGGLHPITRTLERIEQFFTHIGYGIAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESTQPPIRIVCPGRVYRCDSDITHSPMFHQVEGLLIDRDINFADLKGTIEEFLRVFFEKELAVRFRPSFFPFTEPSAEVDIQCVMCSGKGCRVCKQTGWLEVLGCGMVHPNVLRMSGIDPEEFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLAQFR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCS_SHEHH
Sequence: MKLPIYLDYAATTPVDPRVAEKMMQCLTMDGIFGNPASRSHRYGWQAEEAVDIARNQVADLINADPREIVFTSGATESDNLAIKGVAHFYHKKGKHIITSKTEHKAVLDTCRQLEREGYEVTYLQPEPSGLIPVAMIEAAMREDTILVSIMQVNNEIGVIQDIDAIGELCRSRKIIFHVDAAQSAGKLPIDVQTTKVDLMSISGHKMYGPKGIGALYVSRKPRIRLEAAMHGGGHERGMRSGTLATHQIVGMGEAAAIAKADMVVDNERIARLRDKLWNGIKHIEETYINGDVEKRACGSLNVSFNFVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTDEEIDHAIETIKESIGNLREMSPLWEMFKDGIDLDSVQWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_SHEDO
Sequence: MSKPEYFIGLMSGTSMDGVDAVLVDFSQAKPQLIAGHTQAIPKHLLKGLQRLCNPAADEINRLGRLDRAVGSLFADAVNALLEKTNIPKSQIIAIGSHGQTVRHMPNLEVGFTLQIGDPNTIAVETGIDVIADFRRKDIALGGQGAPLVPAFHQQVFAEKDQIRVILNIGGIANVTYLPGNSEQVLGFDTGPGNTLIDAYILQNLEQAFDEDGQWADSGNSNQALLTQMLSHPYFSLHYPKSTGRELFNQAWLEQQLANFSHLDAEDIQSTLLDLTCHSIANDINKLAPKGQLFVCGGGALNGALMKRLTQLVPGYQLQTTSALGVDAKWVEGIAFAWLAMRHHHNLPANLPAVTGASKSAVLGGRYSAK
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RL11_CANAL
Sequence: MSDKSQNVMRELRIEKLVLNICVGESGDRLTRAAKVLEQLSGQTPVQSKARYTVRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRSKNFSATGNFGFGIDEHIDLGIKYDPSIGIYGMDFYVVMGRAGARVTRRKRARSTIGNSHKTNKEDTIQWFKTRYDAEVLDK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: CLPX_XANCP
Sequence: MSEDRQGRSGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSSLPKPREILEVLDQYVIGQLRAKRTLAVAVYNHYKRIESRSKNDEVELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTKNILFICGGAFAGLDKVIQARSNDAGGIGFGAKVKSSERKQEVGKILAEVEPEDLIKFGLIPEFVGRLPVVATLEELDEPALIKILTEPKNAITKQFKKLFEMESVELEFRPDALSAIAKKALKRKTGARGLRTIVESVLLDTMYELPSQENVSKVVVDESVIEHKSEPYLIYQAQPAPAKAASGD
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: METK_DEIDV
Sequence: MRKFYTSESVSEGHPDKLADFISDSILDEFLRQEPTSRVAVETLVTTGMAVVAGEVRAITAHVDVQKTVRDAVMKVGYTRANYGFDAEYSAVLVSIHEQSPEIAEGVDHSEEWRGMSEAERALPENAYSLVGAGDQGLMFGYATDETPELMPLPISLAHQLTRRLAELRKNGTLPYLRPDAKAQVTVVRDGDVHDASETLVDTIVISTQHGEDVTQEQIRQDMLKHVIQAVIPAEYLTPDTKYFINPSGRFVIGGPHGDTGLTGRKIIVDTYGGAVPHGGGAFSGKDPTKVDRSAAYYARYIAKNIVAAGLARRALVEVAYAIGRAHPVSLRVDTYGTGTVSDERLAQLVEAHFDARPQAIIAQLDLQRPIYAQTAAYGHFGRPEFPWEQTDRAEALRQAAQG
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXH_BLOPB
Sequence: MSILFISDVHLSTKSPYITDGFLRFLSYRAMRAKALYILGDLFETWLGDDDYNLLHINIAKALKALNQRRISCYFIHGNHDFLLGQRYARACGMTLLSSNQVLKLASGKKIIILHGDILCANDNSYQLFRKYLRHIIVQRLFLSLPLSIRSRIFSAIRSCCVQHTKYKSKKKLNINLKIATDMLIQNNADIMIHGHTHQPAIHKIYRSKKNVFRIIVLGCWNKYGSMIEVNEKNNDILFTEFPLYEITKY
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VIT1_EUCGR
Sequence: MADGANDGGNPGAEEQQRLLDQHKEAHFTAGEIVRDIIIGVSDGLTVPFALAAGLSGANASSSIVLTAGIAEVAAGAISMGLGGYLAAKSEADNYARELKREQEEIIRVPDTEAAEVAEILARYGIEPHEYGPVVNALRKKPQAWLDFMMKFELGLEKPDPKRALQSAFTIAIAYVLGGLVPLIPYMFIPVARKAVVASVILTLMALLIFGYAKGYFTDNKPFKSALQTALIGAIASAAAFGMAKAVQS
What is the function of this protein?
Vacuolar iron transporter involved in the transfer of iron ions from the cytosol to the vacuole for intracellular iron storage (PubMed:30742036).  Can transport cobalt ions from the cytosol to the vacuole (PubMed:30742036).
What are the official names of this protein?
Vacuolar iron transporter 1, EgVIT1.
What is the protein family that this protein belongs to?
Belongs to the CCC1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RLMG_VIBVU
Sequence: MKTELNLFDRQLTLFRYPNNANETLQAWDAGDEYLINYVEELALDTPQNILILNDHFGALSCWFSAQHQVTMMSDSFISQQGAKENLQRNQCREVKLLTTLDAIPTETSLVLFQLPKNNRHLTWQLTQLRKTLSPDVPVVAVNKAKEIHTSTLKLFEKYLGTTKTSLAWKKHRLVFCQADCAQMNDISPVTRWNVEEHKMTLNNLPNVYSGESLDLGARFMLEHIPQDDNLKHIIDLGCGNGVLSVKAAQLNPKAKFTLVDESYMAIESARLNLQENVTASVDAEYIANNCLDGFAGEIADLILCNPPFHQQQAITDHIAWQMFCDAKRVLKRGGKLQVIGNRHLGYDGKLKRLYGDKNVKLVASNSKFVILQATK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4C_PANGI
Sequence: MNFFPWLTIIVVLPIFAGSVIFFLPHRGNRVIRWYTICICILELLLTTYAFCYHFQFDDPLIQLVEDYKWINFFAFHWRLGIDGLSIGPILLTGFITTLATLAARPVTRDSRLFHFLMLAMYSGQIGSFSSRDLLLFFIMWEFELIPVYLLLSIWGGKRRLYSATNFILYTAGGSIFLLMGVLGVGLYGSNEPTLNFETSVNQSYPVALEIIFYIGFFIAFAVKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLIRINMELLPHAHSIFSPWLVIVGTIQIIYAASTSPGQRNLKKRIAYSSVSHMGFILIGIGSITDTGLNGAILQIISHGFIGAALFFLAGTSYDRIRLVYLDEMGGIAIPMPKIFTMFTSFSMASLALPGMSGFVAELIVFFGIITSQKYLLMPKILITFVMAIGMILTPIYSLSMLRQMFYGYKLFNAPNSYVFDSGPRELFVSISIFLPVIGIGMYPDFVLSLSVDKVEVILSNFFYR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MUTL_LISW6
Sequence: MAKHIVELTDALSNKIAAGEVVERPASVVKELVENAIDAGSTVIDILVEEAGLNKITIIDNGSGIEEEDVATAFLRHATSKIKNEADLFRVHTLGFRGEALPSIASVSHLSMETSTGETKGTTISLEGGKIMEQKSGHARKGTQIEVSQLFFNTPARLKYLKSLPTELGNITDILNRLALAHPDISFRFSHNGKPLLQTNGNGDLRQVIAAIYGVSIARKSIPVKAESLDFNISGYAVLPEVNRSNRNYISTIINGRFIKNFALVKAIQEGYHTLLPIGRFPIIVLQIEMDPIIVDVNVHPAKLEVRLSKEKELGQLISQMIKEAFHQLQLIPDGEVSKKQKEQQKSEQIQMSFEENKLPKETPTLFSKPNVPEYVPSDEDTSREDDFILETLPTYDSKIQPEQAEEPKERIPKMYPIGQMHATYIFAQNENGLYIIDQHAAQERIKYEFYREKIGEVSRELQELLVPIVLEFPTDEYVRLEEQKTKLEEVGVFLENFGQNSFIIRAHPTWFPKNQEEEMLREIIDEALSAPSISIHKLREDTAIMMSCKKSIKANHYLTMQDMEALLDTLREASDPFTCPHGRPVIIQYSTYELEKMFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: GPR_HALH5
Sequence: MVKELNLEQYNVRTDLAIEAHDIVKEQEAQEAKQPASTVEGFDIEETVMDGVKVSKVVIHPLGAERTGKKAGRYLTFESQGIRKKDTDIQEKMERVFAQQFSQFMGELGITKDHTCLVVGLGNWNVTPDALGPITVENLLVTRHLFTLAPEEVGEGFRPVSAIAPGVMGVTGIETSDVIYGIIEQTKPDFVIAVDALASRSIERVNATIQVSDTGIHPGSGVGNKRKELSKETLGIPVIAVGIPTVVDAVTITSDAIDYVLKHFGRELREREKPSRALAPAGMTFGERRELTDEDLPPEEKRKTFLGMMGTLPEGEKRQLIQEVLAPLGHNLMVTPKEVDVFIEDMANVIASGLNAALHQGVNQDNVGAYTH
What is the function of this protein?
Initiates the rapid degradation of small, acid-soluble proteins during spore germination.
What are the official names of this protein?
Germination protease, GPR endopeptidase, Germination proteinase, Spore protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A25 family.
Protein: FKB1A_BOVIN
Sequence: MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFVLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPNATLIFDVELLKLE
What is the function of this protein?
Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand.  May modulate the RYR1 calcium channel activity.  PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, Calstabin-1, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IDHP_MOUSE
Sequence: MAGYLRAVSSLCRASGSARTWAPAALTVPSWPEQPRRHYAEKRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ
What is the function of this protein?
Plays a role in intermediary metabolism and energy production (PubMed:8867815).  It may tightly associate or interact with the pyruvate dehydrogenase complex (PubMed:8867815).
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], mitochondrial, IDH, ICD-M, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NADD_SALAR
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLSRVIIMPNNVPPHRPQPEASSAQRKYMLELAIADKPLFTLDERELQRNAPSYTAQTLKAWREEQGPEAPLAFIIGQDSLLNFPTWHDYDTILDNTHLIVCRRPGYPLEMTQAQHQQWLEQHLTHTPDDLHQLPAGKIYLAETPWLNISATLIRERLEKGESCDDLLPENVLNYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: OE18_NPVOP
Sequence: MIYTDPATGATTNTDAAGNNYLNRLTPNTFLIILAVVVIVALIIIFMQSSSNGNNSSSPAAVPQMGFPLNTTMRANPFVATPQRL
What is the function of this protein?
Component of the polyhedra envelope.
What are the official names of this protein?
Occlusion-derived virus envelope protein E18, ODV-E18.
What are the subcellular locations of this protein?
Virion membrane.
Protein: F16PA_ACIF5
Sequence: MHIGTTLSQFIIEETRLYPGASGDFAGLLNDLTTSCKFIGAQVYRGALVGALGSAGTDNVQGEVQKKLDIISNEAILKSMDWTGHLAGMASEEMDDPYPIPRNIPRGKYLLLFDPLDGSSNTDVGISVGTIFSILKAPVAGRDAELADFLQPGVEQVCAGYALYGSSNMLVYSTGYGVNGFTLDPSIGEYILTHNQMRIPEDTSEYAINMSNHRHWQKPVQRYIDELNQGTDGPRQRDFNMRWVGSMVADVHRILCRGGIFLYPFDQRDPKKPGKLRLLYEANPMSYLVEQAGGAASTGTTRILDIVPQGLHQRIPVILGAKNEVERVVAYHQGSFVIP
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAP2A_THEAO
Sequence: DCLGFMKPCDINNDKCCSSYVCGRNNHWCKFHL
What is the function of this protein?
Gating-modifier toxin that inhibits both sodium (Nav) and calcium (Cav3) channels by inducing hyperpolarizing shift in voltage-dependence of activation and steady state inactivation.  Inhibits Nav1. 1/SCN1A, Nav1. 2/SCN2A, Nav1. 6/SCN6A, Nav1. 7/SCN9A and Cav3. 1/CACNA1G sodium and calcium channels at nanomolar concentrations (IC(50)=169-621 nM).  Surprisingly, selectively slows fast inactivation of Nav1. 3/SCN3A.  Also shows moderate inhibition of Nav1. 3/SCN3A sodium channels (IC(50)=1216 nM).
What are the official names of this protein?
Mu/omega-theraphotoxin-Tap2a, Mu/omega-TRTX-Tap2a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 59 (Tltx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL28_SOLM1
Sequence: MAKICDHCGKKPQSGNNVSHANNKSKRRFEPNLVSVRAQLPSGEVKTVTVCTRCLRSGAVVKPVAKHA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: BIOB1_CORDI
Sequence: MIIARIFGHLPIATTWEHHVTDILELARTKVLNNGEGLNKEEVLQVLQLDEARIPELLELAHEVRLKWCGEEVEVEGIISLKTGGCPEDCHFCSQSGLFESPVRSAWLDIAGLVEAAKQTQKSGATEFCIVAAVKGPDERLMSQLEEAVAAIKSEVDIEVAASIGILTQEQVDRLKAAGVHRYNHNLETARSYFPNVVTTHSWESRRETLRMVGEAGMEVCSGGIIGMGETLEQRAEFACDLAELNPTEVPMNFLDPRPGTPFADYEVLDTTDALRAIGAFRLALPKTILRFAGGRELTLGDLGTEQGLLGGINAVIVGNYLTTLGRPMEQDLDMLGKLRLPIKALNASV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RS9_STRPD
Sequence: MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADLRLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAGLLTRDARMVERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CASA2_CAVPO
Sequence: MKLFIFTCLLAVALAKHKSEQQSSSEESVSISQEKFKDKNMDTISSEETICASLCKEATKNTPKMAFFSRSSSEEFADIHRENKKDQLYQKWMVPQYNPDFYQRPVVMSPWNQIYTRPYPIVLPTLGKEQISTIEDILKKTTAVESSSSSSTEKSTDVFIKKTKMDEVQKLIQSLLNIIHEYSQKAFWSQTLEDVDQYLKFVMPWNHYNTNADQVDASQERQA
What is the function of this protein?
Important role in the capacity of milk to transport calcium phosphate.
What are the official names of this protein?
Alpha-S2-casein, Casein-A.
What is the protein family that this protein belongs to?
Belongs to the alpha-casein family.
What are the subcellular locations of this protein?
Secreted.