PharMolix/UniProtQA huggingface dataset:
Protein: REM8_ARATH
Sequence: MANASQLSPTNKHFFKPLLPGFQRNLNIPVKFFSEHIEGKHEGETVKLRADASKRTWEVKMDGNRLTEGWKEFVEAHDLRIRDFVVFRHEGDMVFHVTALGPSCCEIQYPQSISHEEGEESGEVEISEREVEENLQKEYDQSSADLNCFSQSVTHSNISNDLVTLPRDFAKRNGLDKGMHEIVLMNEEGKSWESEVRSRMSGQVFIVGGWKSLCSENKLKGGDSCTFKLLQNAKTPVFQLCSRIGESRFVKLTPTLNSLEIGKQHLPVSFTKGNGLIHPGEIILVDKDRVEWSMKLQVDNRGGMHIFGGNDWKSFCAANEVGAGESLTLELIRGGLSPLFKFFSKIEQPSFEAEDRRHKRARVHNGSQETDKGEPSRATKMGPELEKREKTAEKGEPSRASNKSSGKQGNLQKTQACSVTDHVAKVKESVVDTLTSIRRFQAELETMEQKLEDSLQEINKLS
What are the official names of this protein?
B3 domain-containing protein REM8, Auxin response factor 24, Protein REPRODUCTIVE MERISTEM 8.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPT4H_CAEBR
Sequence: MAASIPSDLRNLRACLLCSLIKSVDAFQTDGCENCDEVLHLKGDEEKVYDCTSANYDGMIAAMSNDDSWVCKWQKMQRRVKGIYAISVSGSLPSNVVSDLKSMGVRYKANQRDYSIQAKK
What is the function of this protein?
May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.  DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT4, DRB sensitivity-inducing factor small subunit, DSIF small subunit.
What is the protein family that this protein belongs to?
Belongs to the SPT4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DADA_PARDP
Sequence: MKIVVLGAGVLGVTSAWYLAKAGHEVTVIDRQEGPALETSFANAGEISPGYSSPWAAPGVPLKALKWMFQRHAPLVVQPRLDWQRVSWMARMLANCTSSAYAVNKSRMVRLAEYSRDCLGELRAETGIRYDERTQGTLQVFRKQQQLDAAGKDIEVLRADGVPFEVLDRDGCVAAEPGLAGSAERIVGGLRLPGDETGDCFLFTNRLAEMATEAGVTFRWGVSIEALEAEGGRISAVRTDKGRLTADRYVLAMGSYSPRMVRHLGLKLPVYPLKGYSLTIDIQDESRAPVSTVMDETYKVAITRLGDRIRVGGLAEIAGYDLSLNPRRKETLAKSVGELFGGAGDAEQALFWTGLRPMTPDGTPIVGATPIPNLYLNTGHGTLGWTMSAGSGRLIADLISGRKPDIAAEDLGYARYMRGAKAAGRPALQPARA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: MIBS_STRLS
Sequence: MPDSGSLGPPTSLPEQPPAPPATAPDAPAATVTDRPVTSSVAHFLAGLHPPVTRPSSPPSPSMPPASSNPSSPPSSSMPPASWAPPSPLSPPAPSLPPTSPPATAPETSAATGSDSVVRRVPVGPTGLGTTALSLARRQAAVPPDAVPAPSGPSAEGPVVPGLYHHPIPEPDPVRVAEVSRRIKRWAEDEVRLYPEEWEGQFDGFSVGRYMVACHPDAPTVDHLMLATRLMVAENAVDDCYCEDHGGSPVGLGGRLLLAHTALDHLHTTAEYAPEWSESLGSDAPRRAYRSAMDHFVRAATPSQADRYRHDMARLHLGYLAEAAWAETGHVPEVCEYLAMRQFNNFRPCPTITDTVGGYELPADLHARPDMQRVIALAGNATTIVNDLYSYTKELDSPGRHLNLPVVIAEREHLSDRDAYLKAVEVHNELMHAFEAAAAELAADCPVPAVLRFLRGVAAWVDGNHDWHRTNTYRYSLPDFW
What is the function of this protein?
Catalyzes the cyclization of 2-methylgeranyl diphosphate (2-MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate.
What are the official names of this protein?
2-methylisoborneol synthase, 2-MIB synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily.
Protein: RL9_PSESM
Sequence: MQLILLEKVANLGNLGDKVNVKAGYGRNYLLPYGKATAATAANVAAFEERRAELEKLAADKKASAETRAAQLAELEVTITATAGDEGKLFGSIGTHDIADALTASGVEVAKSEVRLPNGTIRNVGEFDVAVHLHSDVEATVRVVVVAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: UD73_DORVU
Sequence: MPKSLLLVLALALLAQTALANGPQGSSDRNWIRLG
What is the function of this protein?
Probable toxin.  Shows a moderate antiparasitic activity against the major pathogenic nematode of ruminants (H. contortus, EC(50)=94. 5 uM).  Does not show insecticidal and antimicrobial activities.  Does not induce increase in intracellular calcium in mouse DRG neurons, suggesting that it does not induce pain.
What are the official names of this protein?
U-limacoditoxin(13)-Dv73, U-LCTX(13)-Dv73, Cecropin-like peptide, Vulnericin.
What is the protein family that this protein belongs to?
Belongs to the limacoditoxin-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_PSEMY
Sequence: MARYIGPKCKLSRREGTDLFLKSGVRALESKCNIEAAPGIHGQRRGRQSDYGTQLREKQKVRRIYGVLERQFSGYYKQAASQKGATGENLLQLLECRLDNVVYRMGFGATRAESRQLVSHKAISVNGQTVNVPSYQVKAGDVVAVREKSKNQLRIAQALELCAQRGRVEWVEVDAEKKSGVFKNVPARGDLSADINESLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL3_STAHJ
Sequence: MTKGILGRKIGMTQVFGENGELIPVTVVEASQNVVLQKKTEEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKAGAAPKRFIREFRNVNVDEYEVGQEVTVDTFEAGDIIDVTGTSKGKGFQGAIKRHGQARGPMAHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENNVILVKGNVPGPKKGFVEIQTSIKKGNK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GPDA_BAUCH
Sequence: MSAVITSMIVIGAGSYGTALAITLARNGNKVLLWGHDPVHVQAMKVARCNHAFLPNVIFPSTLYLETSLPVALTASRNVLIVVPSNVFGSVLTRIKPHLRPDARIVWATKGLEMNTGRLLQDVARDILGGHIPLAVISGPTFARELAAGLPTAIAIAATDVTFSADLQQLLHCSKSLLVECNIDFIGVQLGGALKNIIAIGAGISDGLGFGANARAALITRGLAEISRLGKAMGATPSTFMGMAGLGDLVLTCTDNQSRNRRFGILIGQGIEVQTAQKNIGLVVEGYTNTKDVLKLASRYRVVMPITEQLYQILYHNKNVYDAALTLLGRYYKDKQISYL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1C_SACHY
Sequence: MTEKKNRREKKNPREAKVTFEGLVTEALPNGMFRVRLENDTIILGYISGKIRSSSIRILMGDRVKIEVSRYDSSKGRIIYRLPHKDSKRTEDSKDTEDLKDTKDSKD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y145_RICCN
Sequence: MKILKSLVLLVLFMAMPAKADDAFSWMSTSFGGLKSLFGCLEVPEFTSFQEGNIGISLSTAGIWQSTGNTVQKGKLLKINWSTSGITLEPRKYLVLYRIDPRFSMPQVFIKTYNYSKLQFEALGFPRFVTDNNSETPGTIPPDKDLDALSFTKMSDFVKYFNYSNGNSRIEVKAGDVVNISLVGKDNFFSPNTLKLPNTVDNILTQELDSSIFAASALYTQSNLGDFDNRIIYSSAEQVCNMIDKERKSVCSGTGTATKYKNTDNGVIVGKPMITGAVQYFMGLIKACPANAGINTSPACYYDQGRGMIIKVGGQVIKGQDQSFVNSGSTQSSFIYYQATSGGIMDFTSDWQVSNMFSNSVLMNDWSRNFSNYASFVDYINKNDWSANFLYFGCYSMIVEIGNGANLINPDDQQNIKLEYLITSDGTLPDPSVRGMPVDYNFATDAPQDGYLWLRVVNPNSNIQGVVSVNYANYTGTTWFSDIIYNGAIKPITDQFRTFSQNFYIKLVKNSAVQNLAKTALTLYVTIFGLMFVTGALKLTAVEVITRICKIAIVAFLIREESWSFFNTYFFSAFTDGIDFFVTNVVGATSSRSNIFGFIDPIFDKYTNGRIWGLLFIELLQIHNGLAFIAIITIYSLITYFRAILEVIIGYVIAFIGVTVMISLAPFFIILMLFEKTKSLFDNWISTLLSYVVQPTILLIFFLLIDQVLSEQLLKVVVRACWDTLIPIKIGLDLTNLGIPIHFSFTLPFLPGIPFYVPDVPEISSSNILTNNANTFLVLFTTALLFYSYCLMSYSLVTFVNIVVGMLTNVTPARISGNYQERSDPVGAVMQDIDSVTKPIKKAAMAPARVFKDKIIDQNYKARKAEVGGEFTNKFLAERNDVKKEEGEKKE
What are the official names of this protein?
Uncharacterized protein RC0145.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARLY_NEIMA
Sequence: MHDKTWSGRFNEPVSELVKQYTASIGFDRRLAEWDIQGSLAHAQMLKETGVLDEGDLADIRRGMAEILEEIRSGKIEWSSDLEDVHMNIERRLTDKIGDAGKRLHTGRSRNDQVATDIRLWLRDQITVIQSLIQSLQTALLDLAEQNAETVMPGFTHLQVAQPVSFGHHMLAYVEMLGRDNERMADCRRRVNRMPLGAAALAGTTYPIRREITAELLGFEQICQNSLDAVSDRDFAVEFTAAASLIMVHLSRLSEELILWMSPRFGFIDIADRFCTGSSIMPQKKNPDVPELVRGKSGRVIGHLIGLITLMKSQPLAYNKDNQEDKEPLFDTADTLIDTLRIYADMMRGVTVKPDNMRAAVMQGFATATDLADYLVKKGMPFRDAHEVVAQAVRHADEAGVDLSELPLEVLQGFSDLIADDVYGVLTPEGSLNARNHLGGSAPEQVRFQVKRWREMSA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2094_SHIFL
Sequence: MLSGYRVFSRRYVKSFPCLSRGFEIETELTIHALELRMKYGEVNTKYGERSEGSVSKLSTWSDGFKILKTIIKLYSLERPLYFFSIIGVLLAALSIILGLPIIVDYIDTGLVRRFPTAFLTASIMLSSIMAFVCGIILHSNTTTRREMKALFYLSEKNYKLIM
What are the official names of this protein?
Uncharacterized protein SF2094/S2216, ORF10X9.
Protein: RPOZ_RUEST
Sequence: MARVTVEDCVDKVPNRFELVMLAAHRAREISAGAELTVDRDNDKNPVVSLREIAEETQSADALRERLIESNQSQIEVDEPEEDSMALLMGGEADKPQEDDMSEEKLLRALMEAQGQG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RECA_STRSV
Sequence: MAKKQKKLDEISKKFGDERQKALDNALKNIEKDFGKGAIMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPSYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGNTQIKGTGDEKDTNVGKETKIKVVKNKVAPPFKEAFVEIMYGEGISKTGELIKIATDLDIIKKAGAWYSYNDEKIGQGSENAKKYLADHPEVFGEIDRQVRVRYGLIDGDDMAEAVGNKAESPVETLEEVTLDLDDAIEIEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_HISS2
Sequence: MSNLQNIIECAFERVAEITPTNAEAELRAAVDEAIEGLDKGIYRVAEKNEQGEWIVNQWLKKAVLLSFRLNDNVVVDGAETKYYDKVPVKFADYDVERFKTEGFRAVPGAVVRKGSHISKGVVLMPSFVNIGAYVGEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIGDNCFIGARSEIVEGVIVEEGCVISMGVFIGQSTKIYDRETGEIFYGRVPAGSVVVSGSLPSKCGKYNLYCAVIVKKVDAKTLGKVGINELLRTIE
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAP_ASPFU
Sequence: MLGFSSLRRYLSSFTTRPLRRIESAKQLAKTMTVLPNTYDEPVRIAVIGGTGLRELPGFTQVASLSITTPWGSPSSPITILHHQCSHNNKTVAVAFLSRHGTHHQIAPHEVPARANIAALRSIGVRTIIAFSAVGSLQEEIKPRDFVIPDQVIDRTKGVRPWTFFEGGVVAHVPFGDPFDEGVAKVVRACGHSLEGEGVVLHDRGTLICMEGPQFSTRAESNLYRSWGGSVINMSCLPEAKLAREAEIAYQMICMSTDYDCWHESTADVTVEMVMGHMKANAQNARRFVTAVLDALASDEHADLVQAKHVEGSIKFGLSTAQANWSPEARAKLEWLFPGYWN
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: METK_MOOTA
Sequence: MTRKLFTSESVTEGHPDKIADRIADAVLDAIYAKDNQARVACECLVSTGLILVAGQITTDCYVDIPRVARETVREIGYTRAKFGFDCDTCAVITSIDEQSPDIAMGVNEAWEKKQGEARDEVETLGAGDQGMMFGYATSETPEFMPMPIALAHALTRRLAAVRKERILPYLRPDGKSQVTVEYEDGRPVRVDTVVISTQHRPDIDMATLRDEVLETVIKPVIPAEMLDNRTRYFINPTGRFVIGGPQGDTGLTGRKLIVDTYGGMARHGGGALSGKDPTKVDRSAAYAARYVAKNVVAAGLADRCEVQVAYAIGVARPVSISVETFGTGKVSDDRLVELIRAHFDLRPGAIIRDLDLRRPIYKAVSVYGHFGRPDLDLPWERLDKVEALRADAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIT1_ARATH
Sequence: MASLALSGSCSLAFPLKSRSLSLPRPPSSSLNLTKPLRSLDSRFSLLKSPLPVSLRRRSSTLVKASSTVASASSSPTPPLVPAPVPWQGAAIKPLLASIATGLILWFVPVPEGVTRNAWQLLAIFLATIVGIITQPLPLGAVALMGLGASVLTKTLTFAAAFSAFGDPIPWLIALAFFFARGFIKTGLGNRVAYQFVRLFGSSSLGLGYSLVFSEALLAPAIPSVSARAGGIFLPLVKSLCVACGSNVGDGTEHRLGSWLMLTCFQTSVISSSMFLTAMAANPLSANLAFNTIKQTIGWTDWAKAAIVPGLVSLIVVPFLLYLIYPPTVKSSPDAPKLAQEKLDKMGPMSKNELIMAATLFLTVGLWIFGAKLGVDAVTAAILGLSVLLVTGVVTWKECLAESVAWDTLTWFAALIAMAGYLNKYGLIEWFSQTVVKFVGGLGLSWQLSFGILVLLYFYTHYFFASGAAHIGAMFTAFLSVSTALGTPPYFAALVLAFLSNLMGGLTHYGIGSAPIFYGANYVPLAKWWGYGFLISIVNILIWLGVGGAWWKFIGLW
What is the function of this protein?
2-oxoglutarate/malate translocator involved with DIT2-1 in primary ammonia assimilation and in the re-assimilation of ammonia generated by the photorespiratory pathway.  Imports 2-oxoglutarate into plastids as precursor for ammonia assimilation.  2-oxoglutarate is converted to glutamate, the end product of ammonia assimilation, which is exported to the cytosol by DIT2-1.
What are the official names of this protein?
Dicarboxylate transporter 1, chloroplastic, 2-oxoglutarate/malate translocator 1, AtpOMT1.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: Y1807_NEIMF
Sequence: MNASNWSVYLILCENSAFYCGISPNPQQRLAAHTTGKGAKYTRVFKPVAMRIVAGGMDKGTALRQEIAVKKLTAAQKRQLWEQAEKMPSET
What are the official names of this protein?
UPF0213 protein NMC1807.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: RL28_STACT
Sequence: MGKQCYVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: YHAM_BACAC
Sequence: MKKKIAEYEVGEQVDVFLLIKTATKGIASNGKPFLTVILQDPSGDIEAKLWDVSPEVEKQYVAETIVKVAGDILNYKGRIQLRVKQIRVANENEVTDISDFVEKAPVKKEDMVEKITQYIFEMRNPNIQRLTRHLLNKHQNEFLDYPAATKNHHEFVSGLAYHVVSMLDLAKAISNLYPSLDKDLLYAGVILHDLGKVIELSGPISTTYTLEGNLLGHISIMVNEIGKAADELQIDAEEVLILQHIVLSHHGKAEWGSPKPPLVKEAEILHYIDNLDAKMNMMDRALGRTKPGEYTERVFALDNRSFYKPSFHN
What is the function of this protein?
Shows a 3'-5' exoribonuclease activity.
What are the official names of this protein?
3'-5' exoribonuclease YhaM.
What is the protein family that this protein belongs to?
Belongs to the YhaM family.
Protein: CCNF_RAT
Sequence: MGSGGVIHCRCAKCFCYPTKRRIKRRPRNLTILSLPEDVLFHILKWLSVGDILAVRAVHSHLKYLVDNHASVWASASFQELWPSPQNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEACAEVNGLKASRFFSMAERLNTGSDPFIWLFIRPPWSVSGSCCKAVVHDSLRAECQLQRSHKASILHCLGRVLNLFEDEEKRKQAHNLFEESAHQGCLASSYLLWESDRKVDMSDPGRCLHSFRKLRDYAAKGCWEAQLALAKACAGGSQLGLEGKACSESVCQLFQASQAVNKQQIFSVQKGLSDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYKLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRVMGEIISALEGKIRIPTVVDYKEVLLTLVPVAPRTQHLCSFLCELTLLHTSLSVYAPARLASAALLLARLMHGHTQPWTTQLWDLTGFSYSDLTPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKCYEEISQEEVLSYAELCSALGVKQESPEPPSFPSSGEIHTFLSSPSGRRSKRKRENSLQEDRGSFVTTPTAELSNQEETLLGSLLDWSLDCCSGYEGDQESEGEKEGDVTAPSGLLDVTVVYLNPEEHCCQESSDEEVWPEDKSHPTPGTQAPPASAPWPLPCNRGDPGKDVTTSGYSSVSSSSPISSLDGGMVGSPRSTSVLSVGSHSSTKPCYHQAKKSCLQCRPPNPPESGAHQQPVKRQNLSVHSDEDTNLGFLKL
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  The SCF(CCNF) E3 ubiquitin-protein ligase complex is an integral component of the ubiquitin proteasome system (UPS) and links proteasome degradation to the cell cycle (By similarity).  Mediates the substrate recognition and the proteasomal degradation of various target proteins involved in the regulation of cell cycle progression and in the maintenance of genome stability (By similarity).  Mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication (By similarity).  In G2, mediates the ubiquitination and proteasomal degradation of CDC6, thereby suppressing DNA re-replication and preventing genome instability (By similarity).  Involved in the ubiquitination and degradation of the substrate adapter CDH1 of the anaphase-promoting complex (APC/C), thereby acting as an antagonist of APC/C in regulating G1 progression and S phase entry (By similarity).  May play a role in the G2 cell cycle checkpoint control after DNA damage, possibly by promoting the ubiquitination of MYBL2/BMYB (By similarity).
What are the official names of this protein?
Cyclin-F.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localization in the centrosome is rare in S phase cells and increases in G2 cells, Localizes on both the mother and daughter centrioles. Localization to centrosomes is not dependent on CP110. Localizes to the nucleus in G2 phase.
Protein: CWC25_KLULA
Sequence: MSDLNLLKSWNPKLVKNRKKVWEAQQQLVEENKKIKERQKEIEKERELDRYSSLIRDEDQKNVKRKTGLEWMYDNTSTALTENVDYLLGKKEITDTLLDLSGNNNKSEKSENQKQTIRKHYQGIEDVICSKTNHKNVDLSSDDPMAKFKAAKQAHLKTLKQNIQPTSHEYPVHKPLRGANSKRYDSGNGSRSNYKNSRYNNKYYRS
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC25.
What is the protein family that this protein belongs to?
Belongs to the CWC25 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPE_JANSC
Sequence: MSAATFRGYAPAKVNLALHVTGRRVDGYHELDSLVVFAGVGDRLEIAPADALSLTVTGPRAEGVPDDARNLVWKAADWLAPGRGAAMTLDKHLPHAGGIGGGSADAACALRGLAEIWDVDVPDGAEALGADVPVCLHGQPVRMRGIGDVLDAVPPLPPMWIVLVNAGVEVPTGAVFKAMERVDNPPLPAPAWDGFDSFLVWLERTRNDMESSARSQAPVIGMVLERLRALPGCRFTRMSGSGGTCFGLFETEIAARDAALGLPKHWWVTYAPVLRA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ABC3G_CHLAE
Sequence: MNPQIRNMVEQMEPDIFVYYFNNRPILSGRNTVWLCYEVKTKDPSGPPLDANIFQGKLYPEAKDHPEMKFLHWFRKWRQLHRDQEYEVTWYVSWSPCTRCANSVATFLAEDPKVTLTIFVARLYYFWKPDYQQALRILCQERGGPHATMKIMNYNEFQHCWNEFVDGQGKPFKPRKNLPKHYTLLHATLGELLRHVMDPGTFTSNFNNKPWVSGQRETYLCYKVERSHNDTWVLLNQHRGFLRNQAPDRHGFPKGRHAELCFLDLIPFWKLDDQQYRVTCFTSWSPCFSCAQKMAKFISNNKHVSLCIFAARIYDDQGRCQEGLRTLHRDGAKIAVMNYSEFEYCWDTFVDRQGRPFQPWDGLDEHSQALSGRLRAI
What is the function of this protein?
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms.  Exhibits antiviral activity against vif-deficient: HIV-1 and simian immunodeficiency viruses (SIVs) and also simian foamy virus (SFV).  After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA.  The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells.  Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA.  May inhibit the mobility of LTR retrotransposons.
What are the official names of this protein?
DNA dC->dU-editing enzyme APOBEC-3G, Deoxycytidine deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Mainly cytoplasmic, small amount are found in the nucleus.
Protein: METAS_EDWI9
Sequence: MPIRIPDALPAVNFLRNENVFVMTDSRAAVQEIRPLKVLLLNLMPKKIETENQFLRLLSNSPLQIDIQLLRIDRRESKNTPMEHLNNFYCHFEDIQQENFDGLVVTGAPLGQVDFGDVAYWSQIVQVIEWARAHVTSTLFVCWAAQAALNILYGLPKMTRAQKLSGVYEHQTLNPLALLTRGFDEGFLAPHSRYADFPPQAIREHTDLQIFAESAQAGAYLFASVDKRTVFVTGHPEYDAHTLGAEYWRDLHAGLTPALPFNYFPQDNSDGTPLATWRSHGHLLFSNWLNYCVYQITPYDLRQMNPTLE
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECPB_KLEP3
Sequence: MKKHLLALGLLLVGVSPAQALDVGDISSFMNSGSSTLSKTIKNSTDSGRLINIHLERLSSPLDGGQVIPMDKPDEVLLTPASLLLPAQASDVIRFFYKGPADDKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQVNYRFQYANGSLTNTGNATLRILAYGPCLKAADGKECKENYYLMPGKSRRFTQVDTANKKGRVALWQGEQFVPVK
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP plays a dual role in early-stage biofilm development and host cell recognition (By similarity).
What are the official names of this protein?
Probable fimbrial chaperone EcpB.
What is the protein family that this protein belongs to?
Belongs to the EcpB/EcpE family.
Protein: M_EAVBU
Sequence: MGAIDSFCGDGILGEYLDYFILSVPLLLLLTRYVASGLVYVLTALFYSFVLAAYIWFVIVGRAFSTAYAFVLLAAFLLLVMRMIVGMMPRLRSIFNHRQLVVADFVDTPSGPVPIPRSTTQVVVRGNGYTAVGNKLVDGVKTITSAGRLFSKRTAATAYKLQ
What is the function of this protein?
Major envelope protein.
What are the official names of this protein?
Membrane protein, Protein M.
What is the protein family that this protein belongs to?
Belongs to the arteriviridae membrane protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host membrane; Multi-pass membrane protein.