PharMolix/UniProtQA huggingface dataset:
Protein: DEF_PROMA
Sequence: MARSFSQLAINAEKQRTSLAVSKKPTDQPELEIHTLGNSALRQSAKRISKVDKNIRDLVKKMLHSMYAAKGIGLAAPQIGSQQQLLVIDLDIENSATPPIILINPEITEFSATIDTYEEGCLSIPGVYLDVIRPSSIKVNFRDEMGRPKKINADGLLARCIQHEMDHLNGVLFVDRAINEEALNKELKEHGFKKKDVLRLCSD
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: FEPB_ECOL6
Sequence: MRLAPLYRNALLLTGLLLSGIAAVQAADWPRQITDSRGTHTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLYIGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLDRLKALF
What is the function of this protein?
Part of the ABC transporter complex FepBDGC involved in ferric enterobactin uptake (By similarity).  Binds ferric enterobactin (By similarity).
What are the official names of this protein?
Ferric enterobactin-binding periplasmic protein FepB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 8 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ARLY_MANSM
Sequence: MALWGGRFTQAADQRFKDFNDSLRFDYRLAEQDIEGSVGWSKALVSVGVLTTDEQQQLERALNELLIEVRSNPQAILQDDAEDIHSWVESKLIDKVGNLGKKLHTGRSRNDQVALDIKMWCKAQVTELQYAVRDLQAKLVETAENNQHAVMPGYTHLQRAQPISFAHWCMAYVEMLERDYSRLADAYNRMDSCPLGSGALAGTAYPVDREQLAKDLGFAFATRNSLDSVSDRDHIIELLSTASLSMVHLSRFAEDMIIFNSGEADFVELSDRVTSGSSLMPQKKNPDACELIRGKAGRVIGSLTGMMVTVKGLPLAYNKDMQEDKEGIFDALDTWHDCLTMAAFVLEDIRVNVERTREAALKGYSNATELADYLVAKGVPFRDSHHIVGETVVYAIKVHKGLEDLSIEEFRQFSDVVGEDVYPILSLQSCLDKRSAKGGVSPLRVAEAIADAKARIAAKK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE5A_BPV4
Sequence: MQHCILILAWGKCILKAKFFLPLLPVRFVLGDPEDNAGTQTGDPARGR
What are the official names of this protein?
Probable protein E5A.
Protein: CSRA_ECOSM
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: NAPA_YERPS
Sequence: MKLSRRDFMKANAAVAAAAAAGMTIPTVAKAVGETTNAIKWDKAPCRFCGTGCGVLVGTQNGRIVASQGDPDSPVNRGLNCIKGYFLPKIMYGKDRLTQPLLRMKDGQYDKEGDFTPISWEKAFDIMELKFKNALKEKGPTAVGMFGSGQWTVWEGYAALKLLKGGFRSNNLDPNARHCMASSVVGFMRTFGMDEPMGCYDDIEEADAFVLWGSNMAEMHPVLWSRMTSRRLTNAHVRIAVLSTYEHRSFELADNPIVFTPQTDLVIMNYIANYIIQNNAVDKDFLAQHVNFRRGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDFKTFVAEYTLEKTAKMSGVPEDQLESLAQLYADPKVKLVSYWTMGFNQHTRGVWANNMCYNLHLLTGKISTPGSGPFSLTGQPSACGTAREVGTFSHRLPADMVVTNEKHRQIAETTWQLPAGTIPEKVGLHAVAQDRALKDGTLNAYWVMCNNNMQAGPNINEERMPGWRDPRNFIVVSDPYPTISALSADLILPTSMWVEKEGAYGNAERRTQFWRQQVPSPGEAKSDLWQIVEFAKRFNVEEVWPAELVNQKPEYRGKNLYEVLFANDVVSKYPLSEIPDDQLNDEARDFGFYIQKGLFEEYASFGRGHAHDLAPFDVYHQVRGLRWPVVDGKETLWRYREGFDPFVPKGEEVRFYGKPDGKAVIFALPYEPAAESPDQEYDLWLSTGRVLEHWHTGSMTRRVPELHRAFPEAVLFIHPLDAKARGLHRGDKVKVISRRGEVISLVETRGRNRPPRGLVYMPFFDAAQLVNNLTLDATDPLSKETDFKKCAVKLERVVA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYK_AGRFC
Sequence: MTDTKTETTALSSDATEVRRQKLALLREQIGDVYPAHFHRTLSNAELAEKYADIEADVETGDTVTVAGRVYSSRNSGMFMDIHDASGKVQIFSHKDTTPEAARNLLPMIDIGDIIGVTGKVRRTKRGELTINAEEITMLTKSLLPMPEKWHGVSDIELRYRKRHLDILANEDSKLRFLQRSKILSGIRRFMEAEGFLEVETPMLQTVYGGATADPFKTFHNTLKMDMYLRIAPELFLKRTLVSGLSDKVFEINRNFRNEGVSTRHNPEFTMMECYWAYADYEDIMGLVERLFETLAIALHGTTEVEFQGQTISFKGPFKRVPMPDAVKEATGIDFLAIKTDEEARAAAKAAGFAVEKDWTWGECLAFIFEEKVEATLIQPSHVTHFPKDISPFAKEVPGEPRLVERFESYCNAWEVGNAFSELNDPEEQRRRMVEQLEQAHARGEKDKQLDDEFLDAIDQGMPPAGGLGIGVDRLIMLLTNAPSIRDVILFPARRNKAD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_LEGPC
Sequence: MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGIGVDDIEVDTLMSRQSQVALNEANVILFLVDGRSGLTGIDQQIAQALRKLNKKVHLVVNKTDGMNEDIACADFQSLGITDVHAISASHGGGISSLLEEILEPFTTETHEATDDKAIKIAFAGRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDEKIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEEDHKEKIKSELSRRLHFANFAKIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLLQDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLDALPESYKRYLNNEFIKHLGLVGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ACPS_CAMJD
Sequence: MRVGCDIIAISRIEKIHSRHGKNFLDKFLSPKEQILIKNPATLAGLWAAKEAASKALGVGICELCSFFDIEISKDERNAPKLKYSQKITKDFNITQTSLSISHDNGFAIAIVAIV
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_ACIBT
Sequence: MQLTEQQQDKLSKVQLEESWKRSLTPFLLSPYMDSLRDFLFQQKQAQKTIYPPSKQIFNALNITPLDHVKVVILGQDPYHGPNQANGLSFSVQRGVALPPSLRNIFHELHTDLGVPVSRHGDLTKWAEQGVLLLNSVLTVEAGQPTSHQKQGWEEFTDAVIDVLNEQREHIVFILWGAYAQRKGQRINREKHLVLTAAHPSPLAANRGGFFGCKVFSKTNQYLKQHGIEPIDWQLDA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTRB_MOUSE
Sequence: MKGFKLSCTASNSNRSTPACSPILRKRSRSPTPQNQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDDDFNTMGYCEEIPIEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFDGLPLEEEVMEGDGSLEKELAIDNIIGEKIEIMAPVTSPSLDFNDNEDIPTELSDSSDTHDEGEVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFTNSPFLRDFMEQRRFSDIIFHPWKKEENGNQSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYTINRYTLTRVARNKSRLRVSTELRYRKQPWGFVKTFIEKNFWSGLEDYFRHLETELTKTESTYLAEIHRQSPKEKASKSSAVRRRKRPHAHLRVPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPEDTPDGFHLQSVSKLLLVISCVICFSLVLLVVLNMMLFYKLWMLEYTTQTLTAWQGLRLQERLPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVLLLDQMKDSLINLQNGIRSRDYTAESDEKRNRYH
What is the function of this protein?
Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (PubMed:30220461).  Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (PubMed:30220461).  Plays a crucial role in cholesterol homeostasis in the adrenal gland and has the unique ability to localize to the PM based on the level of membrane cholesterol (PubMed:30220461).  In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain (PubMed:30220461).  At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER (PubMed:30220461).
What are the official names of this protein?
Protein Aster-B, GRAM domain-containing protein 1B.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. Note=In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS).
Protein: RUVC_PSYIN
Sequence: MSIILGIDPGSRITGYGVVQQKGSKCIYIASGCIRTKGDTLAPKLDMIFNGISEIIKQYQPTEFGIEQVFMAKNPDSALKLGQARGAAIVAATQADLYVCEYSARQIKQAVSGSGGATKEQVQQMVMQILNLSGRPQADAADGLAVAICHAHTAQTIVAMSGKVSKTVRGRFR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: LNP1_HUMAN
Sequence: MEHKDDDDDDVSFAKWMSSFWGHSWREEDQRGLRERHRLQATSHRKTSLPCPLPVLPRIPSSDCHPRRHSHEDQEFRCRSHVRDYRKYSEDGSFKEPLESKGRSHSKIEKFSESFERQLCFRTKRSASLGPESRKERNERECLRMEIKSRKKVEEERSSRKEEHGEAHMAPLFEKGPE
What are the official names of this protein?
Leukemia NUP98 fusion partner 1.
Protein: MNME_HAEDU
Sequence: MKETIVAQATPIGRGGVGILRVSGPLAQQVAQEILGKTLTPRLAHYLPFKDNDGEILDQGIALFFKAPNSFTGEDVLELQGHGGQVILDLLLKRILTINGIRIARTGEFSEQAFLNDKLDLAQAEAIADLIDATSEQAARSALKSLQGEFSNKINQLVDQVIYLRTYVEAAIDFPDEEIDFLADGKIERHLNDIIHQLAAVRQEAKQGSILREGMKAVIAGRPNAGKSSLLNALAGREAAIVTNIAGTTRDVLHEHIHLDGMPLHIIDTAGLREASDEVEKIGIQRAWNEIVAADHVLLMLDSTEQSAYAFKTEWAEFLAKLPPKMPITIIRNKVDLSGEVEGLTQLDGFTLIRLSAQTKIGVDVLREHLKTSMGYQSSTEGGFLARRRHLQALETAAKHLTQGHIQLTQFFAGELLAEELRLVQNTLSEITGQFTSDDLLGNIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN274_MACFA
Sequence: MASRLPTAWSCEPVNFEDVTLGFTPEEWGLLDLKQKSLYREVMLENYRNLVSVEHQLSKPDVVSQLEEAEDFWPVERGIPQDTIPEYSELQLDPKLDPLPAESPLMNIEVVEVLTLNQEVAGPRNAQIQALYAEDGSLSPDAPSEEVQQQGKHPGDPEAARQRFRQFRYKDMTGPREALDQLRQLCHQWLQPEARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQEVVALVEGVTWISEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVTVLSEEPVTFQDVAVDFSREEWGLLGPTQRTEYRDVMLETFGHLVSVGWETTLENKELAPNSDIPQEEPAPSLKVQESSRDCTLSSTLEDTLQGGVQEVQETVLKQVESAKEKDLPQKKHFDNHESQANSGTLDTNQVSLQKIDSVESQVNNGALNTNQVLLQKIPPRKQLRKCDSQVKSMKHNSRVKIHQKSYERQKAKEGNGCRKTFSRSAKQITFIRIHKGSQVCRCSECGKIFRNPRYFSVHKKIHTGERPYVCQACGKGFVQSSSLTQHQRVHSGERPFECHECGRTFNDRSAISQHLRTHTGAKPYKCQDCGKAFRQSSHLIRHQRTHTGERPYACNKCGKAFTQSSHLIGHQRTHNRTKRKKKQPTS
What is the function of this protein?
Probable transcription repressor.  Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression.  The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions (By similarity).
What are the official names of this protein?
Neurotrophin receptor-interacting factor homolog, Zinc finger protein 274.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: GATA_HERAR
Sequence: MHTKTIKELSALLQTKKISATELAQLFLKRMGASDLNAFLHVDEALTLQQAAAADQRIASGNAGVLTGIPIAHKDIFVTRNWRSTAGSKMLENYVSPFDATVVENFNQAGMVTLGKLNCDEFAMGSSNENSYFGAVKNPWDKTAIPGGSSGGSAAAIAARLTPASTATDTGGSIRQPAALCGVTGIKPTYGRVSRFGMIAFASSLDQGGPIAKTAEDCGLLLNAMVSFDERDSTSVERDKEDFTRDLNAPLEGLKIGIPREYFGAGLSADVEQAVRAALGEYEKLGATLVDISLPKTELSIPTYYVIAPAEASSNLSRFDGVRYGFRAKDYTDLSDMYCKTRAEGFGEEVKRRILVGAYVLSHGYYDAYYLQAQKIRRLIAQDFQQAFTLCDVIMGPVAPSVAWDLGDKADDPVANYLADIFTLSTSLAGLPGMSIPCGFGQGEKNAKRPVGLQIIGNYFAEAKLLNVAHQYQQATDWHLRQPAE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: GPA33_MOUSE
Sequence: MLGKAGSVVWMLCAIWVAADALTVETTQDILRAARGRSVTLPCTYNTYVSDREGFIQWDKLLRSQTERVVTWNFVTKKYIYGNRYENRVRVSNDAELSNASITIDQLTMDDNGTYECSVSLMSDQDVNAKSRVRLLVLVPPSKPDCSIQGEMVIGNNIQLTCHSAEGSPSPQYSWKSYNAQNQQRPLTQPVSGEPLLLKNISTETAGYYICTSSNDVGIESCNITVAPRPPSMNIALYAGIAGGVFVALIIIGVIVYCCCCREKDDKDQDREDARPNRAAYQVPKKEQKEISRGREDEDDHRHEDRWSSGRSTPDQPFQ
What is the function of this protein?
May play a role in cell-cell recognition and signaling.
What are the official names of this protein?
Cell surface A33 antigen, Glycoprotein A33, mA33.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: IHFA_YERPY
Sequence: MALTKAEMSEHLFEKLGLSKRDAKDLVELFFEEVRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVESATPKE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: XPT_BACCQ
Sequence: MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFARKRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_NEIMA
Sequence: MKFVSDLLSVILFFATYTVTKNMIAATAVALVAGVVQAAFLYWKYKKLDTMQWVGLVLIVVFGGATIVLGDSRFIMWKPSVLFWLGALFLWGSHLAGKNGLKASIGREIQLPDAVWAKLTYMWVGFLIFMGIANWFVFTRFESQWVNYKMFGSTALMLVFFIIQGIYLSTCLKKED
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL11_STRSF
Sequence: MPPKKKKVTGLIKLQIKAGAANPAPPVGPALGQHGVNIMEFCKAYNAATESQRGMVVPVEITVYEDRSFTFVTKTPPAARLILKHAGIEKGSGEPHKTKVANVTRDQVREIATIKMPDLNANDLDAAEKIIAGTARSMGVTVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: BKRB2_MOUSE
Sequence: MPCSWKLLGFLSVHEPMPTAASFGIEMFNVTTQVLGSALNGTLSKDNCPDTEWWSWLNAIQAPFLWVLFLLAALENLFVLSVFFLHKNSCTVAEIYLGNLAAADLILACGLPFWAITIANNFDWVFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMREYSEEGHNVTACVIVYPSRSWEVFTNVLLNLVGFLLPLSVITFCTVRILQVLRNNEMKKFKEVQTERKATVLVLAVLGLFVLCWVPFQISTFLDTLLRLGVLSGCWDEHAVDVITQISSYVAYSNSGLNPLVYVIVGKRFRKKSREVYRVLCQKGGCMGEPVQMENSMGTLRTSISVERQIHKLQDWAGKKQ
What is the function of this protein?
Receptor for bradykinin.  It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
B2 bradykinin receptor, B2R, BK-2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MATK_OENGL
Sequence: MEEFPGYFELDRSRQHDFLYPLIFRESIYALAHDHGLNRNRSTLFENEVDYDKKYSLIIVKRLITRMYQRNHLIISANGSVQNPFWGHNKNLYSKILSEGFAVIVEIPFSLRVLSSFERKEKDIAKSPTLRSIHSIFPFLEDQFSHLDYLSHVLIPYPIHLEIAVQTLRYWVKDASSLHLLRIFLHEYWNSFSTPKKHITLFLKGNSRFFLFLYNSYVCEYESIFLFIRNQSSHFQSTSSGVFFERILFYVKIDHLVEVFVGTDFLDIRSFFKDPNMHYVRYQGKSILASKDTPLLMNKWKYYLVNLWQYHFSVWSQPGRININQLGKYSLDFLGYFSNVQLKSSVVRNQTLENSFLINNAMKKLETTVPILPLIGSLSRAKFCNALGHPISKPTRTDSSDSDIIDRFVRICRNLSHYHSGSSKKKSLYRIKYILRLSCVKTLARKHKSSVRAFLKRLGSELGDEFLTEEGVVLAVIFPKASGRLYRGRIWYLDIPCINDRVGDAEGSIFTK
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MYO1G_MOUSE
Sequence: MLAVGRMEDEEGPEYGKPDFVLLDQLTMEDFMKNLELRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAKYQGRELYERPPHLYAVANAAYKAMKRRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRAEVERVKNVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPVGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDQELQGLHLERNPAVYNFTRQGAGLNMGVHNALDSDEKSHQGVMEAMRIIGFSPDEVESIHRILAAILHLGNIEFVETEENGPQKGGLEVADEALVGYVAKLTATPRDLVLRTLLARTVASGGREVIEKSHTVAEASYARDACAKAMYQRLFEWVVNKINSIMEPRNRDPRCDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLILKQEQEEYEREGIAWQTIEYFNNATIVELVEQPHRGILAVLDEACSTAGPITDRIFLQTLDTHHRHHPHYSSRQLCPTDKTMEFGRDFQIKHYAGDVTYSVEGFIDKNRDSLFQDFKRLLYNSVDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVRCIKPNEDKVAGRLDEAHCRHQVEYLGLLENVRVRRAGFASRQPYPRFLLRYKMTCEYTWPNHLLGSDRDAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQKAWRGTLARWHCRRLRAIYTIMRWFRRHKVRAHLIELQRRFQAARQPPLYGRDLVWPTPPAVLQPFQDTCRVLFSRWRARQLVKNIPPSDMIQIKAKVAAMGALQGLRQDWGCQRAWARDYLSSDTDNPTASHLFAEQLKALREKDGFGSVLFSSHVRKVNRFRKSRDRALLLTDRYLYKLEPGRQYRVMRAVPLEAVTGLSVTSGRDQLVVLHAQGYDDLVVCLHRSQPPLDNRIGELVGMLAAHCQGEGRTLEVRVSDCIPLSQRGARRLISVEPRPEQPEPDFQSSRSTFTLLWPSH
What is the function of this protein?
Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration (PubMed:25083865).  Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements.  Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication (PubMed:25083865).  Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes (PubMed:24310084).  Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis (PubMed:23038771).
What are the official names of this protein?
Unconventional myosin-Ig.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell projection, phagocytic cup. Note=Recruited to Fc-gamma receptor (Fc-gamma-R) phagocytic cup (PubMed:23038771). In T-cells, transiently accumulates in discrete areas at the plasma membrane of migrating cells or when membranes are deformed (PubMed:25083865).
Protein: GRWD1_BOVIN
Sequence: MAALKGRRRTCEPGESMETESQETGSKGQAQVYLPGRGPPLREGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESSQSNRLMMLRMHNLHGTKPPPPEGSDDEEEEDDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFALRRLLQVVDDPQALATFLRDEQTRMKPIFAFSGHMGEGFALDWSPRVPGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTEDTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVINWSHREPFLLSGGDDGALKVWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADNQITQWDLAVERDPEAGDAETDPGLADLPQQLLFVHQGETDLKELHWHPQCPGVLVSTALSGFTVFRTISV
What is the function of this protein?
Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness.
What are the official names of this protein?
Glutamate-rich WD repeat-containing protein 1.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus. Chromosome. Note=Present in the nucleus throughout interphase and is detached from chromatin at the onset of mitosis and rebinds at telophase when the pre-replication complexes (pre-RC) is formed.
Protein: E6_FOWPN
Sequence: MDFIRRKYLIYTVENNINFFTQELADKISNFCLNHVVAINYIIKKYHKSVLTKDIFNNTNFYIFLHFIRDCETYDIVLKSSFDVTLLYLNQLVKNYTSFTDFIDIYKQQSNTLLDDKRFLFVTKLSPYFQDIISVNFSTELNPLFHLNEPIKDLEIIYSKLFKETRFIKVDRISVLRLLIWAYSLKMDTGMKFDDNDSHDLYTILQKTGPVVSSIMTETFKEFVFPKNSTTSYWLFMKERIYNDEKVYTNEPAITIYEKVLSYIYSEIKQARVNKNMLKVVYMLDSDSEIKKFMLELIYGIPGDILSIIDERDETWKSYFVDFYHDNFIDDKTFTSANRFYDDLFNVIAKIDPEKFDIRRDIESIFRTDATLVKRFDDMKINSTYVSQMIYQTQNVDLLALENKKLCQIYNKDTEYAIKEYNTYLYLNEDNPIVIYKGELKKLSDLDLNSPSIVFSLFSKSLLKYYLDSKLASLGLIIENYKDDIILKIITGSSCLQNFTSFIVYATCNDKSILKSVVRTIINHFKVAIIILFKQFLQENIYYVNEYLDNTKHLSKNDKKFILQIINGNYD
What is the function of this protein?
Late protein which may play a role in the virion morphogenesis and have therefore an indirect role on viral transcription ability.
What are the official names of this protein?
Protein E6 homolog.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae E6 family.
What are the subcellular locations of this protein?
Virion. Note=Localizes in the mature virion (MV).