PharMolix/UniProtQA huggingface dataset:
Protein: LACR_STAAC
Sequence: MNKHERLDEIAKLVNKKGTIRTNEIVEGLNVSDMTVRRDLIELENKGILTKIHGGARSNSTFQYKEISHKEKHTRQIAEKRFIAKKAASLIEDGDTLFFGPGTTVELLAEEVNHHTLTIITNCLPVYKILLEKQTAHFRVYLIGGEMRHITEAFVGEMANAMLEKLRFSKMFFSSNAVNKGAVMTSTLDEAYTQQLALSNSIEKYLLIDHTKVGKEDFTSFCQLNELTAVVMDYEDEEKVETIKTYIEVVD
What is the function of this protein?
Repressor of the lactose catabolism operon.  Galactose-6-phosphate is the inducer (By similarity).
What are the official names of this protein?
Lactose phosphotransferase system repressor.
Protein: ALLA_PSE14
Sequence: MRKLIIEPLTKEAFAPFGDVIETDGSDHFMINNGSTMRFHRLAEVQTAQPDDKAIISIFRAEALPMPLTIGMLERHPQGSQAFIPLLGNPFLIVVAPVGDAPESELTRAFVSNGRQGVNYHRGVWHHPVLTIEKRDDFLVVDRSGEGNNCDEHYFAESQLLVLDPNPLEG
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the utilization of allantoin as nitrogen source.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: MURB_BACP2
Sequence: MENLKNELLEAQVGKVLENEPLANHTTMKIGGPADLLIIPKDIDAVKTIMDHVKKHQTNWTVIGRGSNLLVLDKGIRGVVLKLGTGLDHLTVNDEEITVGGGYSVVRLATSLSKQGLSGLEFAAGIPGSIGGAVYMNAGAHGSDISKILVKARILFEDGSIEWLTNEQMNFSYRTSVLQKERPGIVLEAVFKLKQDDREKITKKMQQNKDYRKETQPYNRPCAGSIFRNPLPEYAGQLVEKANLKGYQLGGARISDMHGNFIVNAGGATAQDVLDLIQFIQKKIKEDYNVEMHTEVEIIGEEN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BDNF_PTYMJ
Sequence: MTILFLTMVISYLSCMKATPMKEVSIRGQGSLAYPGLRTQGNLETLSGPNDATRGLTSLADTFEHVIEELLDERQVIQPSKENKDADLYSSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSTSEWVTAAEKKTAVDMSGATVTVLEKVPVPKGQLKQYFYETKCSTKGYAKEGCRGIDKRYWNSQCRTTQSYVRALTTDNKKRVGWRFIRIDTSCVCTLTIKRGR
What is the function of this protein?
Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PME_BRANA
Sequence: MAVGKIVISVASMLLVVGVAIGVVTFVNKGGGAGGDKTLNSHQKAVESLCASATDKGSCAKTLDPVKSDDPSKLIKAFMLATKDAVTKSTNFTASTEEGMGKNINATSKAVLDYCKRVLMYALEDLETIVEEMGEDLQQSGSKMDQLKQWLTGVFNYQTDCIDDIEESELRKVMGEGIAHSKILSSNAIDIFHALTTAMSQMNVKVDDMKKGNLGETPAPDRDLLEDLDQKGLPKWHSDKDRKLMAQAGRPGAPADEGIGEGGGGGGKIKPTHVVAKDGSGQFKTISEAVKACPEKNPGRCIIYIKAGVYKEQVTIPKKVNNVFMFGDGATQTIITFDRSVGLSPGTTTSLSGTVQVESEGFMAKWIGFQNTAGPLGHQAVAFRVNGDRAVIFNCRFDGYQDTLYVNNGRQFYRNIVVSGTVDFIFGKSATVIQNSLILCRKGSPGQTNHVTADGNEKGKAVKIGIVLHNCRIMADKELEADRLTVKSYLGRPWKPFATTAVIGTEIGDLIQPTGWNEWQGEKFHLTATYVEFNNRGPGANTAARVPWAKMAKSAAEVERFTVANWLTPANWIQEANVPVQLGL
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Probable pectinesterase/pectinesterase inhibitor.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: TRMN6_ALIFM
Sequence: MSKSFTFKQFHIDIGSCGMPVSTDGVLLGAWTNISECSQILDIGAGTGLLSLMSAQRNSNAHIDAIELMPIAAEVARLNFSQSPWKERLVLIHQDFLSYQTAYEYDAIICNPPYFNNGEQSLKGERSTARHTDSLPFDKLLQHCKTLISSTGRASFILPVFEGEIFIKIAKGCDFHLTKITKVKTTEKKSPTRLLIELSLFPHIYQESTLTIHDGNGYSDDFIKLTRMFYLNMG
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRSF2_RAT
Sequence: MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS
What is the function of this protein?
Necessary for the splicing of pre-mRNA.  It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly.  It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA.  The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment (By similarity).
What are the official names of this protein?
Serine/arginine-rich splicing factor 2, Splicing component, 35 kDa, Splicing factor SC35, SC-35, Splicing factor, arginine/serine-rich 2.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUA_UREPA
Sequence: MNYKISLRYDGSLFYGWARQPQKRTVQGDLEEIFKSIFKINNIRIIGSGRTDKGVHAYEQTFSVKHSALKYDSHIIYQALCSRTSSDIQILEVQKVDDSFHAQYNATSKTYQYVINDYEFDLFRNNYELFVNQKINDQKILEALELFVGEHDFKSFSTSELTMTIRRINWVKIKRDTHLIIYINANGFLKNMVRMIVASCLDYAFNKISLAKIHELLIYPKKGASIKLAPACGLYLYKVYY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RAB8A_BOVIN
Sequence: MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFYTLARDIKAKMDKKLEGNSPQGSNQGVKITPDQQKRSSFFRCVLL
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  That Rab is involved in polarized vesicular trafficking and neurotransmitter release.  Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.  Regulates the compacted morphology of the Golgi (By similarity).  Together with MYO5B and RAB11A participates in epithelial cell polarization.  Also involved in membrane trafficking to the cilium and ciliogenesis (By similarity).  Together with MICALL2, may also regulate adherens junction assembly (By similarity).  May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose homeostasis (By similarity).  Involved in autophagy (By similarity).
What are the official names of this protein?
Ras-related protein Rab-8A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Recycling endosome membrane. Cell projection, cilium. Cytoplasmic vesicle, phagosome membrane; Lipid- anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Midbody. Cytoplasm. Note=Colocalizes with OPTN at the Golgi complex and in vesicular structures close to the plasma membrane. In the GDP-bound form, present in the perinuclear region. Shows a polarized distribution to distal regions of cell protrusions in the GTP-bound form. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB11A in apical membrane initiation sites (AMIS) during the generation of apical surface and lumenogenesis. Localizes to tubular recycling endosome. Recruited to phagosomes containing S.aureus or Mycobacterium (By similarity). Non-phosphorylated RAB8A predominantly localizes to the cytoplasm whereas phosphorylated RAB8A localizes to the membrane (By similarity).
Protein: ACYP_RHIWR
Sequence: MSGADRPDRIARRIHVKGKVQGVWFRAWTVEQAAELGLDGWVRNRADGSVEAVAAGPADRVEEMIARCRRGSPASRVDSIDVEDTPGVVAQGFTQKPTV
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: SYI_CAMJR
Sequence: MDYKETLLLPSTSFAMRANLAELEPQRFKKWFEQNYAYEKMKENRKNAKKSFTLHDGPPYANGHIHIGHALNKILKETIIKTHYFKGESVRFTPGWDCHGLPIEQQVEVKLGEKKKSLSKKEIREFCRQHASEFVDIQREEFKNLGIIADWDKPYLTMKFEFEAAIYRTLCEIAKKGLLCERSKPVFWSWAAKSALAEAEVEYQDKEDYSIFVAFDLDVKACEKLGVSKASTVIWTTTPWTLVANQAIALNPNENYVITKEGLIFASALLKSMVEKGLTSGEIQKELNAKEFEKLEAINPLNGRKSVLIMGEHVLMDGGSGLVHTAPGHGEDDYYACLKYGIEVLMPVDDSGCYDETLRAKGLLPSHLLEEFIGLHIFKANEKILELLGEKLLHSSKFIHSYPFCWRTHKPVIYRATKQWFILMDEPKLQGKTLRECAKEQLLKTTFYPQSGVKRIGSMVENRPDWCISRQRDWGTPIAFFRDKNTKEVIFDDELFDFVAAIFEKHGADAWWEFEIKDLIPTNSKYNAENLEKVYDILDVWFDSGSTFNAVLNSGLYDAGEKRASMYLEGSDQHRGWFQSSLLVGTAINESAPYESILTHGFTTDEKGQKMSKSKGNVIAPEYVAKTYGVEILRLWILLSDYLSDLKISDNILKQVGEQYRKIRNTIRFLLANTNDLKDLEVKEFSFIDKWILSRATKVFKASKEAFFAYEFAKGFSLLLNFLSADLSGIYLDISKDRLYCDSENAQRRKSAQVAMALIAKELLNLLASNLSYSVDEALEHANVLIKGDAKDVFDLSLTQDFDYDFGIDDTFLMSAREKFFEQIDILKKDKIIKSTLELNLNISFNKFPNEELADWFMVSQISNENEEILAEFEVENEKFKITKASLCKCPRCWKLQSKDEETPCLRCEEVLKGIQC
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_PECAS
Sequence: MKGGKRVQPARPNRINREIRANEVRLTGVEGEQLGIVSLNEALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKATKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQQIGIEVLNRVRDDLSELAVVESFPSKIEGRQMIMVLAPKKKQ
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_ALTMD
Sequence: MADENQTNNGEAAGAQAQQGAQFNIQRIYTKDISFESPNAPAIFTKEWKPEIKLDIDTSTNKLEENVFEVVLSVTVTATLGEETAFLCEVQQAGIFAIGEMPDQNKAHTLGSFCPNMLFPYARETISNLVNRGTFPPLNLAPVNFDAIFAAYVQKRAQQAQGEAPKMDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_CLOBL
Sequence: MKEIVLAGGCFWGVEEYMSRIKGIVETKVGYANGIKENPSYEEVCSGTTGHAEACYIKYDESIISLEELLNKFWSIIDPTVLNKQGNDRGTQYRTGIFYLDEKDLNVIIKSKSQEQKNYRKPIVTEVEPLKCFYEAEEYHQKYLKKNPEGYCHIHLG
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TAB1_CAEEL
Sequence: MGDDGFLDQYPANTDAGIGTVHSCRYSKQKNPVQNNDFLSCSMCIHNGPIKLYGIFSGFNGGDSTAKFVMNRLVYEIFGENPITPTLLPYQVVEEFKRKFENVAERYLLMNTDDLNNRLLKLEEQSETGNNAVSEINQKIRQGTTAIVVMIINQDLYVLNCGNSLAIAMNSENVVQLNSNLHNNDNPLEIVRIKGLGINPETVLNPTRAIGDLQRTHLFEETEAFKNAKGPPVISTPDVQYTKIDPSWRHLVLISDGVVQNLKEVEVENIPTEVSVRLIEDHTVTSTAQALVDSFARKHRDAYTMSDDKNFCISNHREEMTVIYVKLEEDYQAALYEQFDSAISTMESTNATLYEPCSTPYVDATNFNSGKNYEKMKKLLLTRPSK
What is the function of this protein?
Involved in the Wnt signaling pathway by regulating mom-4 kinase activity.
What are the official names of this protein?
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, TAB1-like protein 1, TAK1 kinase/MOM-4 binding Protein.
Protein: GSH1_SALEP
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVTEGEAAKEKISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYARIGVEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLADAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCETAQFPLPKVGKDLFRDLKRVAQTLDSIHGGEEYQKVCDELVACFDNPELTFSARILRSMIDEGIGGTGKAFGEAYRNLLREEPLEILQEEEFIAERDASVRRQQEIEAADTEPFAAWLAKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: YQ54_SALTI
Sequence: MFDFPQPGEIYRSAGFPDVAVVGILEDGIPWEMPYRCPDIVWNPYRRKFSILVRILADGRTTDIPLGRFLREFTCDRPDLFKRSPVNRHAVLKEMAGDPELQKWREKYLDIYPQDTVPVSRAAPVAREWREIPRTEPDPETTPDNSYRNYL
What are the official names of this protein?
P4 prophage-derived uncharacterized protein t2654.
Protein: HETE1_PODAS
Sequence: MRLLERDDAGEIRPTKDLPSGKIPPYAILSHTWGPDEEEVSYKDLKDGRAVSKLGYNKIRFCADQAWRDGRKFFWVDTCCIDKSNSTELQEAINSMFRWYRDAAKCYVYLTDVSTDKRDADGDPSWKWAFQKCKWFTRGWTLQELIAPTSVEFFSREKARIGDRNSLERMIHDVTGIPLEALRGSPLSDFSVHDRMAWMKQRNTTREEDMAYSLFGIFDVHLPLIYGEGKEKALERLREKIGKDDGCLADLRVTDPRHDKKRIEAAKGGLLKDSYCWVLSNVQFQQWHDGDDQRLLWINGDPGKGKTMLLCGIIDELKKSTPPGLLSFFFCQATDSRINNATAVLRGLIYLLVSQQPALISHVRRPYDHAGKKMFEGPNVWIVLCEIFTSILQDPGLRMTYLIIDALDECVTDLPQLLELITRTSCTSSPIKWIVSSRNWPDIEEQLETATQKARLSLELNAESISTAVNAFIQNRIDQLAPKTKHDANMIGKIRDYLHSHANGTFLWVALVCQALADPKVKKRHILAKLQTFPRGLDSLYARMLEQIGHSEDAELCKQILAVAAAVRRPISLDELASLVEMPDDVSDDPESLEEIVKLCGSFLIIRERTVYFVHQSAKDFLLGTASDKASNKASQEAFELVFPTGIEDVSYIIFWRSLNVMSQKLRRDIYCLNAPGFLIDNVRVPDPDPLATVRYSCIYWIDHLRDLVSSTSSKWVHLLQDDGDIHRFLTTKYLYWLEALSLLRALPEGINAIRQLESLLGHTIRGRLIAIVRDGYRFALSYRMIIEKAPLQAYTSALVFAPTDSMIKKIFKKEEPGWISTISVVEAEWNACTQTLEGHGSSVLSVAFSADGQRVASGSDDKTIKIWDTASGTGTQTLEGHGGSVWSVAFSPDRERVASGSDDKTIKIWDAASGTCTQTLEGHGGRVQSVAFSPDGQRVASGSDDHTIKIWDAASGTCTQTLEGHGSSVLSVAFSPDGQRVASGSGDKTIKIWDTASGTCTQTLEGHGGSVWSVAFSPDGQRVASGSDDKTIKIWDTASGTCTQTLEGHGGWVQSVVFSPDGQRVASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFSPDGQRVASGSSDNTIKIWDTASGTCTQTLNVGSTATCLSFDYTNAYINTNIGRIQIATATMESLNQLSSPVCYSYGLGQDHRWITCNNQNVLWLPPEYHTSAFTMQGRKIVLGSYSGRIIIFLFSRDV
What is the function of this protein?
Responsible for vegetative incompatibility through specific interactions with different alleles of the unlinked gene, het-c.
What are the official names of this protein?
Vegetative incompatibility protein HET-E-1.
Protein: RL7_BURVG
Sequence: MAIAKEDILAAVEGMTVLELNELVKAFEEKFGVSAAAVAVAGPAGGAAAAVEEKTEFTVVLTEAGSNKVAVIKAVRELTGLGLKEAKDVVDGAPKAVKEGVDKAAAEEAKKKLEEAGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SPB1_YEAST
Sequence: MGKTQKKNSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMKPMPNVITFQSDITTEDCRSKLRGYMKTWKADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNKLIWVFQQLFEKVEATKPPASRNVSAEIFVVCKGFKAPKRLDPRLLDPKEVFEELPDGQQNMESKIYNPEKKVRKRQGYEEGDNLLYHETSILDFVRTEDPISMLGEMNKFTIDENDHEWKILKKLKQTTDEFRSCIEDLKVLGKKDFKMILRWRKIAREILGIEVKDDAKTEIEVVPLTEEEQIEKDLQGLQEKQRLNVKRERRRKNEMKQKELQRMQMNMITPTDIGIEAASLGKESLFNLKTAEKTGILNDLAKGKKRMIFTDDELAKDNDIYIDENIMIKDKDSAADADDLESELNAMYSDYKTRRSERDAKFRAKQARGGDNEEEWTGFNEGSLEKKEEEGKDYIEDNDDEGVEGDSDDDEAITNLISKLKGQEGDHKLSSKARMIFNDPIFNNVEPDLPVNTVNDGIMSSESVGDISKLNKKRKHEEMHQKQDEADSSDESSSDDSDFEIVANDNASEEFDSDYDSEEEKNQTKKEKHSRDIDIATVEAMTLAHQLALGQKNKHDLVDEGFNRYTFRDTENLPDWFLEDEKEHSKINKPITKEAAMAIKEKIKAMNARPIKKVAEAKARKRMRAVARLEKIKKKAGLINDDSDKTEKDKAEEISRLMRKVTKKPKTKPKVTLVVASGRNKGLAGRPKGVKGKYKMVDGVMKNEQRALRRIAKKHHKKK
What is the function of this protein?
Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.  Specifically methylates the guanosine in position 2922 of the 25S rRNA at the stage of 27S pre-rRNA maturation.  Methylates also the uridine in position 2921 in the absence of methylation of this residue guided by snoRNA snR52 at the stage of 35S pre-rRNA maturation.
What are the official names of this protein?
27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 2'-O-ribose RNA methyltransferase SPB1, AdoMet-dependent rRNA methyltransferase SPB1, S-adenosyl-L-methionine-dependent methyltransferase, Suppressor of PAB1 protein 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MINC_CLOK1
Sequence: MIDNNILVKGNKEGINIVININKFKDFEEMLEALVKRLSVGKMFYKGCNLKIITDLKNINEKQSVRLKQVLFEKFLIKDCIFEDSNEKPSKIFSGIYEGRTKFLRKTIRGGQVVNYPGNIVIIGDVNAGSEIYVGGNIVVFGALRGYAHAGFGGNSKAIVAAISLEPEMLQIADLVTRSPDNMKPQYPEVAKIRGNIIIVEPYLPNKFI
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: CBPM_PONAB
Sequence: MDFPCLWLGLLLPLVAALDFNYHHQEGMEAFLKTVAQNYSSITHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPDVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVSGHDPHLTKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSLLHIFFK
What is the function of this protein?
Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins.  It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins (By similarity).
What are the official names of this protein?
Carboxypeptidase M, CPM.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: ILVB1_MYCTU
Sequence: MSAPTKPHSPTFKPEPHSAANEPKHPAARPKHVALQQLTGAQAVIRSLEELGVDVIFGIPGGAVLPVYDPLFDSKKLRHVLVRHEQGAGHAASGYAHVTGRVGVCMATSGPGATNLVTPLADAQMDSIPVVAITGQVGRGLIGTDAFQEADISGITMPITKHNFLVRSGDDIPRVLAEAFHIAASGRPGAVLVDIPKDVLQGQCTFSWPPRMELPGYKPNTKPHSRQVREAAKLIAAARKPVLYVGGGVIRGEATEQLRELAELTGIPVVTTLMARGAFPDSHRQNLGMPGMHGTVAAVAALQRSDLLIALGTRFDDRVTGKLDSFAPEAKVIHADIDPAEIGKNRHADVPIVGDVKAVITELIAMLRHHHIPGTIEMADWWAYLNGVRKTYPLSYGPQSDGSLSPEYVIEKLGEIAGPDAVFVAGVGQHQMWAAQFIRYEKPRSWLNSGGLGTMGFAIPAAMGAKIALPGTEVWAIDGDGCFQMTNQELATCAVEGIPVKVALINNGNLGMVRQWQSLFYAERYSQTDLATHSHRIPDFVKLAEALGCVGLRCEREEDVVDVINQARAINDCPVVIDFIVGADAQVWPMVAAGTSNDEIQAARGIRPLFDDITEGHA
What is the function of this protein?
Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.  Also involved in condensing pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate.
What are the official names of this protein?
Acetolactate synthase large subunit IlvB1, ALS, Acetohydroxy-acid synthase large subunit, AHAS.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: SYN_TREPS
Sequence: MRAMHPLLKEILTHPPSGQHECVHGWVRSKRETKRAVFISLSDGSCPDTLQVTVPLPECSASLSSGAQAEQIPNVRDAVLQGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACNLTVLGEAPAETYPLQKKSHSFEFLRAHAHLRARTSTFAACARVRSALAGAVHRFFSERHFQYVHTPIITASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLTVSGQLQGEAYALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITDCMDVAEEFLAYLLRAALKDCAQDIAFLDERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDVARAPATRLTYTEAIKLLENSGRSFEFPVRWGCDLQSEHECFLTEEVFHGPVIVYDYPKEIKAFYMKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDLRRFGTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPRTADF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_ACIF2
Sequence: MNLPPLTPATLIRRYKRFLADCALASGEIITVHCPNSGSMRSCAEPGQPILISQSGNPKRKLPWTWELYWSGASWVCINTQHPNAVVAEAIAAGDIPALQNYAQLRREVPYGSHERVDVLLSSEGRPPCYVEVKSCTLLEEDGVIRFPDAVSSRALRHLGALTEVVRGGGRAVMLFLIGREDGRGFAPADAIDPAYGKALRRARTDGVEILAYRTRLSPDKISLSVAEPLLF
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: HIS7_MYCBP
Sequence: MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRVSGVPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_STUS1
Sequence: MTEDQLLGPRAHGEPCGSAVLKAVAEDFQVEEVLDIPLSGEGEHLWLWVEKRNLNTEEAAKRIARAAGVPLKLISYAGLKDRQALTRQWFSLHLPGKADPDLAAAEDDSLRLLQRVRHQRKLQRGAHSANGFRLRLTDLHADHAQLDARLERIRAQGVPNYFGLQRFGYEGGNLLGARDFAARAELPVQRNLRSRLLSAGRSYLFNRVLAQRVADGSWAEARVGDLLAFTDSRSFFPAAEAECSDPRLAILDLHPTGPLWGEGGSPAGAEIQALEDAVAASEEPIANWLAQAGMKHERRILRLPIGGLSWHYPGPDILQLEFVLPTGCFATAMVRELVSLAGQTDI
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.