PharMolix/UniProtQA huggingface dataset:
Protein: EI2BB_BOVIN
Sequence: MPGAAAKGSELSERIESFVEALKRGGGRRSSEDMARETLGLLRRIITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLRIIREEYGRLHGRSDESDQQESLHKLLTSGGLSEDFRSHYAQLQSNIIEAINELLVELEGTTENIAAQALEHIHSNEVIMTIGFSRTVEAFLREAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVAGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit beta, eIF-2B GDP-GTP exchange factor subunit beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: B3GN2_MOUSE
Sequence: MSVGRRRVKLLGILMMANVFIYLIVEVSKNSSQDKNGKGGVIIPKEKFWKPPSTPRAYWNREQEKLNRWYNPILNRVANQTGELATSPNTSHLSYCEPDSTVMTAVTDFNNLPDRFKDFLLYLRCRNYSLLIDQPKKCAKKPFLLLAIKSLIPHFARRQAIRESWGRETNVGNQTVVRVFLLGKTPPEDNHPDLSDMLKFESDKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDAEFVFKGDDDVFVNTHHILNYLNSLSKSKAKDLFIGDVIHNAGPHRDKKLKYYIPEVFYTGVYPPYAGGGGFLYSGPLALRLYSATSRVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKKNICSYIDLMLVHSRKPQEMIDIWSQLQSPNLKC
What is the function of this protein?
Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine.  Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains (PubMed:9892646).  Probably constitutes the main polylactosamine synthase (PubMed:17890318).
What are the official names of this protein?
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2, Beta-1,3-N-acetylglucosaminyltransferase 1, BGnT-1, Beta-1,3-Gn-T1, Beta3Gn-T1, Beta-1,3-galactosyltransferase 7, Beta-1,3-GalTase 7, Beta3Gal-T7, Beta3GalT7, b3Gal-T7, Beta-3-Gx-T7, UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, BGnT-2, Beta-1,3-Gn-T2, Beta-1,3-N-acetylglucosaminyltransferase 2, Beta3Gn-T2, UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: XERC_XANAC
Sequence: MSSVDEFLTYLQVERQVSAHTLDAYRRDLAALVVWASEQKTDDGVQDAAVPAETAQFDSAHLRQFVAAEHRRGLSAKSLQRRLSACRSYYAWLLKRGRISASPAAALRAPKAPRKLPQVLDADEAVRLVEVPTDAPLGLRDRALLEVFYSSGLRLSELCALRWRDLDLDSGLVMVLGKGSKQRLVPVGSHAIAALREWRRDSGASADSHVFPGRAGGAISQRAVQIRIKQLAVRQGMFKDVHPHMLRHSFASHILESSGDLRGVQELLGHSDIATTQIYTHLDFQHLAKVYDAAHPRARRKKAAE
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUTE_CAEEL
Sequence: MSQIGGATCTWRYLGRFVTLGIYASVALFVWYTLVPTRSKHKDSIAINNNNADPATALIPVHTKNVVIYAATKFFGHPITTERFLATCPDVQNYCRITQEESEFDNADAVLFHNADYRGSTDKFKKMKSQRKPGVPYVLWSLESPTNDMFRPDSHMINWTMTYRTDSDVWAPYGTIVKLKNPVEVDLNAIWEGKTKTATWLASNCITQNHRFDLIKKIIDNGFEIDIWGNCGKQVSQCAGVDNQESPCVLELIKPYKFYISMENSNCKDYVTEKFWKALNDRMTIPIVLARKYYKDLGVPDSAYIAVDDYATLDEFLAHVKKVNKEKDLFLSYHQWRKEWKVIIGSGFSGWCTLCNKLQDKDYILKNPKSYKDVAWWHSFEMCNNQIASKYL
What is the function of this protein?
Involved in the fucosylation of N-glycans (PubMed:15364955, PubMed:17369288, PubMed:23754284, PubMed:26538210, PubMed:26002521).  Preferentially catalyzes the addition of fucose in alpha 1-3 linkage to the distal GlcNAc residue in N-glycans (PubMed:23754284).  Catalyzes the transfer of fucose to Gal-beta-1-4-GlcNAc-alpha-pNP (LN-pNP) and Gal-beta-1-4-GlcNAc-beta-1-3-Gal-beta-1-4-Glc (LNnT) (PubMed:17369288).  Unlike alpha-(1,3)-fucosyltransferase fut-1, does not transfer fucose to Man-alpha-1-3-(Man-alpha-1-6)-Man-beta-1-4-GlcNAc-beta-1-4-GlcNAc-beta-1-Asn (M3), Man-alpha-1-3-(Man-alpha-1-6)-Man-beta-1-4-GlcNAc-beta-1-4-(Fuc-alpha-1-6)-GlcNAc-beta-1-Asn (M3F6) and GlcNAc-beta-1-2-Man-alpha-1-3-(GlcNAc-beta-1-2-Man-alpha-1-6)-Man-beta-1-4-GlcNAc-beta-1-4(Fuc-alpha-1-6)-GlcNAc-beta-1-Asn (GnM3F6) (PubMed:17369288).
What are the official names of this protein?
Alpha-(1,3)-fucosyltransferase fut-6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: DACT2_MOUSE
Sequence: MWAPSGQGPAGWDRRRVGARLRAALAGLQELQGLRATQQARVRGALGLHPAPGPRGQELRLEAALTALREQLSRLRRQDAGLKTHLDQLDQQISELQLDVSRSSCEALDSDSRPSSGFYELSDAGSCSLSTSCASVCSDRLSPSLGSWLPVFQPSKSRSGIGDWRPRSADETTVPAWSPQLTEDSRLLHGAEGTGRLTGMFRPRPVSTGDLERVLPADVGLQRAGTDAAHLLGQGIEIPAHALDPTYQRDLVARGGQEVYPYPSPLHAVALQSPLFALPKEAPCFDICSPPQEPPLVPVDENRTQPEPIRELGSAEAYIHRLLHLRGQELPLRDVGQEQGGDTAAFPPKPCGQRSESTCQLEKQACGADRGGLKLGRGAAKDSLKQHGPVSLVGAEPLSSPLKEETIPWNPCVHGDNTVGSSPCSQAQQPLNDCGQGPVLSPSRVLGTESPPLAPEPFAYTSCTTGETSPVKLRMGFSQNKAVKVRRRVSEKVPRLGKQLPPQPERQRVTERDPSRPHQGGLSRRPTLAREPPGRSCSESTLYPVPFLVPVVVAQRESYPTSPQAFFPMEAALLSSAARRKQRRWQSTMEISAKAGSVSQPGPSMGLPRSPAKRGSGPRAQSRPTLARQDACARCESDPSEHSADCTSLYHSTIAETSEDEEASDHTANRFGDESSSNDSEGCFRGSRRRLAIGSAEAGQGGWAWPRVPPQQPSRAPGNTRPPLPPVPKLCRIKASKALKKKIRRFQPAALKVMTMV
What is the function of this protein?
Involved in regulation of intracellular signaling pathways during development.  Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1.  May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character.  May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling.
What are the official names of this protein?
Dapper homolog 2, mDpr2, Dapper antagonist of catenin 2.
What is the protein family that this protein belongs to?
Belongs to the dapper family.
Protein: SNF8_XENTR
Sequence: MHRRGVGAGAIAKKKLAEAKYKERGTVLAEDQLLQMSKQLEMFKTNLEEFASKHKQEIRKNPQFRVQFQDMCATIGVDPLASGKGFWSEMLGVGDFYYELGVQIIEVCLALKHHNGGLITLAELHQHVLKGRGKLAQDVSQDDIIRAIKKLKVLGNGFGIIPVGGSYLVQSVPAELNMDHTVVLQLAEKKGFVTVNEIKSSLNWETERAKHVLEHLLKEGLAWIDSQAQGEAQYWLPALFTALYAQQINMDENGGPS
What is the function of this protein?
Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity).
What are the official names of this protein?
Vacuolar-sorting protein SNF8, ESCRT-II complex subunit VPS22.
What is the protein family that this protein belongs to?
Belongs to the SNF8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PESC_LEIBR
Sequence: MAHKKQAWAKRVKKERFKKKYLTRMQATRLLQMESIQFRRLCILKGVYPRALTRSKQKQSGNEKQYYLAREIKWLVRDHIAEKMMTYRAWEKKVKRAEAMGRADDLKALQSSRVKPRHSLVATIKERYPYFIDAIRDVDDAMSMIHMYAFLSPEIKSESTIEIHHSLTSGLSEKAKEMCHRWNRYIARAHVLTKGFISIKGYYYEAIIKGERVRWLCPHEYAHRFPPGIQQYVMLSFLEFYLEMMKFVLFKLESDLARDEADRLAIEDEEGLTRANAEDFASGAALAVLDVGANQAQAKVKEAESKRSLMEEELLKVRELFRGLTFYISREVPAKHFALIINACGGRVATDYVASNITHVVVDRPALPPGWQQHDQMEYVQPQYIFDCLNARQMLPVTGYRIGEDLPPHVSPFSVSITNSAEDNAAVEQVKKDHPRIVGYVPARVHEIRKLINPSYSPVDPEGKVAQLEDEYSDEEMHVAVPEMDMEDDVSLSGDELAEARKKPGWQEEEVTEEVQRPKLSAFKVKKQREMNLMNAPTNEVVARRRQALRKAQENLRQSETPEARLQRKMSEVKRQEAVTRKMQLQVARKKAARFYKMVSGVVQGTAKKAATLEAKAKHIAEGKLHKTEDGKGLVNARLAARRQRAEAKGKKLKEKKADNPYKKLPKWVQ
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: ATP6_RUBXD
Sequence: MEVTQEELRHEILHTWEAAREAWVIHLEIAGINLSINKPVWFLWLGAAITFLFMYVGARTLRDRPGAYQVLVEELFRFGRDMFGGQINEEGRKWFPYSLTLFIFLLVLNIIGLFPNSYPVTSNISFTATLALFTFVLTQYEGVRRNGLVTYLKSWAPADLPAKPLMYPIMWFLHLIQEFTKPLTLALRLYANILAGHLIIFVFLSLILYFGLPTAFVSVPFAVVFYAFEIFVAVIQAYIFAILTQVYIELAMFAEEAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENGB_SHIB3
Sequence: MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALNTLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEYLEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLNMVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: MINE_BRUME
Sequence: MSIFRFFTRQQASAPQARERLQVLLAHERASYGGQSDLVAVLREEILAVIAKHIKVDREKVSVKMDRGDQVSTLEVDIELPLTAKKGRAA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: CHO_SHIFL
Sequence: MVRRLTSPRLEFEAAAIYEYPEHLHSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIADEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPLLSGNYEITELDPANDQRAS
What is the function of this protein?
Incises the DNA at the 3' side of a lesion during nucleotide excision repair.  Incises the DNA farther away from the lesion than UvrC.  Not able to incise the 5' site of a lesion.  When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA.  Then UvrC makes the 5' incision.  The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity).
What are the official names of this protein?
Excinuclease cho, Endonuclease cho, UvrC homolog protein.
Protein: RHOA_RAT
Sequence: MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLIL
What is the function of this protein?
Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.  Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such as cytoskeletal dynamics, cell migration and cell cycle.  Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.  Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis.  Plays an essential role in cleavage furrow formation.  Required for the apical junction formation of keratinocyte cell-cell adhesion.  Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly.  The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex.  It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.  In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization (By similarity).  Regulates KCNA2 potassium channel activity by reducing its location at the cell surface in response to CHRM1 activation; promotes KCNA2 endocytosis (PubMed:9635436).  Acts as an allosteric activator of guanine nucleotide exchange factor ECT2 by binding in its activated GTP-bound form to the PH domain of ECT2 which stimulates the release of PH inhibition and promotes the binding of substrate RHOA to the ECT2 catalytic center (By similarity).  May be an activator of PLCE1 (By similarity).  In neurons, involved in the inhibition of the initial spine growth.  Upon activation by CaMKII, modulates dendritic spine structural plasticity by relaying CaMKII transient activation to synapse-specific, long-term signaling (PubMed:21423166).  Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (By similarity).
What are the official names of this protein?
Transforming protein RhoA.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex. Midbody. Cell projection, lamellipodium. Cell projection, dendrite. Nucleus. Note=Localized to cell-cell contacts in calcium-treated keratinocytes (By similarity). Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in an activated form and in a myosin- and actin-independent manner.
Protein: RK33_SOLLC
Sequence: MAKGKDVRVTVILECTSCVRNSVDKVSRGISRYITQKNRHNTPNRFELKKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RK14_JASNU
Sequence: MIQPQTHLNVADNSGARKLMCIRIIGASNRRYAHIGDVIVAVIKEAVPHMSLEKSEVVRAVIVRTCKELKRDCGMIIRYDDNAAIVIDQKGNPKGSRVFGAIPEELRQFGFTKILSIAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMH_GEOTN
Sequence: MHISIAAVGKLKEKYLIAGVQEYTKRLSAYAKIEIIEVADEKTPERASELEEEQIKQREGERLLAKIPHDAHVIALAIEGKMKSSEQFAARLDELATYGKSKVVFVIGGSLGLSKQVMARADEALSFSKMTFPHQLMRLILLEQIYRAFRINRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_FRATM
Sequence: MNEYNFSDIEKSTQEYWRKNDTFKTIEDNTKEKFYCLSMLPYPSGTLHMGHVRNYTIGDVIARYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQFDSLGFSFDWSREIATCDEDYYKWEQWFFIQLYKKGLAYRKNSVVNWDPVDQTVLANEQVVDGRGWRSGALVEKKEIPQWFLKITDYADELLQDINKLDNWPEAVKTMQINWIGKSKGLTVKFKVKDSNQEIEVFTTRPDTLMGVNYLGIAPEHPLALKEAKSNSQLAEFIEECKKTSTMEADLATQEKKGFKTSIKVIHPISAETIDVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIPLKQVIESNDNKLKIDLEKQAFTEKGILINSGEFDSLNFKNAYQAIKKYLTEQNKGYETTNFRIHDWGISRQRYWGCPIPMIHCDDCGAVPEKEENLPVRLPTDVALTEAGSPLKDIPEFINVACPECGKPAKRETDTFDTFFESSWYYARYTCPTANQMLDQEANYWLPVDKYIGGIEHAIMHLLYARFFHKLMRDQGLVKSDEPFKNLLTQGMVLKDGAKMSKSKGNIVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSETGVEGTNKFLRKVFNYAELNKVIFAKNITLESQKLTKEDKKARFEIHSNLKQAIFDFDKSQFNTVVSACMKILNTLNNYDNLSESVKVEGFSILLRILAPFTPHLCHYLWQQLNLGEDILHTSFPTVDNNALEKDEFLLVVQINGKLKAKLELDASLSSNQVEEVVLADEHVKSFIDNKQVVKVIYVPQKLINIVIK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_ACIAC
Sequence: MDKLLIAADNALRTLFARPRAAQPSPARGLPEGDLSPAQRREAGALMRVNHVGEVCAQALYMGQAAVTRDPALRARLMEAAREETDHLAWTAERLQALGSRPSLLNPLWFAGAFAIGWTAAQVSDAASLGFVVETENQVARHLQGHLERMPPQDAASLAVIERMQADEQRHADDARAAGASDLPAPARVLMAAAARVMTATAHHI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MINC_ALISL
Sequence: MTKTADLKGSNFTLSVLHLPNDDITQALSMLEQKVAQAPSFFASAPVVINIENVSNEINFVDLKLGVERTGMIPVGITGCKDKEKQAQATSAGFAVMTSFTPQQVTQKANMQPTKVVRTPIRSGQQVYAKDADLVILNHVSPGAEVIADGSIHIHGTLRGRAIAGASGQKEAKIFCKNLQAELISIAGNYWLSDQINKEYWHQNVMVTMVEDHIKIDTLTL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: Y1218_NEIMB
Sequence: MTEQKNKTSLIEFPCTFPLKVMGAVHPEFEQAVLDTVRLHAPDTQAHHITTRPSSKGNYTGATVQVKVENQEQLDNIYRALTSHELVKVVL
What are the official names of this protein?
UPF0250 protein NMB1218.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: MTHSD_XENLA
Sequence: MEPGIRVDPGCSKWDIRQKVWDYIENNNLADFPRPVHHRIPNFKESHQACQNIIDLEVFRRTWEVKVDPDKPLEGVRLAALQARKTLLVPTPRLRTGLFNKITPPPGANKEVLRICSTSQGVKDYSVPMGLDAKVQVDLVVVGSVAVSVQGWRIGKGEGFADMEYAMMVSMGAVTEHTVVVTVVHDCQVVDIPEELLEDHDLTVDFILTPTRIIKTDCKRAKPQGIIWSMITREMMGKIPILRNLQDRERRAGKDVSLKDGNASEQGSRQSPLCLPEKELGPCGSVLSEHKHLANAQLHTKLEACNLHDGATVYIGDIPSTTRVSELKSMLRERGAAPLRLTWQGAQHRAFLDYRDVAQAKQALSSLEGISINGISLLVELARTQRPKANGNQGFRNNKLRATNPSTVSQPHIPT
What are the official names of this protein?
Methenyltetrahydrofolate synthase domain-containing protein.
Protein: ACSA_BART1
Sequence: MTEKIYPISEEIKKNTLLDEETYQKWYRESINDPESFWAKHGQCIEWFKPFTKVKNTSFNDGVSIQWYEDGITNVAYNCIDRHLKTHGDQIALIWEGDNPYHDKKITYNELYEHVCRFANLLKNHGVKKGDKVTIYLPMIPEAAYAMLACARIGAVHSVIFAGFSAEAIAGRIVDCESTFIITADHGLRGGKRINLKDNVDHAIEIAARQNVRVDQVMVIRRTCGPIDWIEGRDFWYHEEITHAKTNCPAEPMNAEDPLFILYTSGSTGKPKGVLHSTGGYLVYAAITHKYVFDYHPGEIYWCTADIGWITGHSYLVYGPLCNGATTLMFEGTPTFPDKGRFWEIVDKHKVNTLYTAPTAIRALMGAGNSFVEHSKRTSLRLLGTVGEPINPEAWEWFYHTVGNDRCPILDTWWQTETGGHMITPLPGATPLKAGSATRPFFGVQLQIIDEQGNILEGEAEGNLCIIDSWPGQMRTLYKDHERFIETYFSTYKGKYFTGDGCRRDSDGYYWITGRVDDILNVSGHRLGTAEIESALVLHPAVSEAAVVGYPHPIKGQGVYSFVTLMEGTAPSEELQKDLIKHVRKEIGSIAILDKIQFAPQLPKTRSGKIMRRILRKIAENNFDNLGDISTLAEPQVVEDLIANRQN
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RSMA_LISMH
Sequence: MSKDIATPGRTTEILKKYGFLFKKSLGQNFLIDSNILTRITDTAEITKETNVIEIGPGIGALTEQLAKTANEVVAFEIDQRLLPILDDTLSAYSNVQVVHGDVLKADVEEVVAEQFAKPELPLKIVANLPYYVTTPIILKLLHDNIPADSMTFMLQKEVADRISAVPSTKSYGSLTIAIQFYMEAELAFIVPKTVFMPQPNVDSAVIHLKRRKEPLAEVNDEEFFFEVTRASFAQRRKTLWNNLASKFPALKPRKDELVEGLNAIGIDLIRRGETLDIPEFAKLSNFLGDFLKEK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_PONAB
Sequence: METVVRSCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEMNAVRKEVAETSGGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLLQDDLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLELEPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.
What are the official names of this protein?
5-aminolevulinate synthase, non-specific, mitochondrial, ALAS-H, 5-aminolevulinic acid synthase 1, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: CRCB1_STAHJ
Sequence: MIHILFIMVGGGIGAVIRAWLTDVFKSKITSPIPIATLIVNLVGSFLIGFVYGIAQDYQLFSLFFITGVLGGLTTFSTLSYEIVQFISPSFKPVQFFSYSILQFVIGFISCFIGYSI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL1_LISMC
Sequence: MAKKGKKYQDALKQIDANKVYTAEEAVELAKKIDFAKFDATVEVAFRLGVDPKKADQQIRGAVVLPNGTGKTQRVLVFAKGEKAKEAEAAGADYVGESEFVEKINQGWFEFDVIVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVTKAVNEIKAGKVEYRVDKAGNVHAAIGKVSFDAAKLVENFRTVNDVLQKAKPAAAKGTYVKNLSVTTTFGPGIKVDPASL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.