PharMolix/UniProtQA huggingface dataset:
Protein: STP4_PIG
Sequence: AKVSRKPREPRTAVTQSTRRIKRKKTLSKPRSRGGVKAPKTTMKIKRALRRNLRRKIQTSAGQPKKAKKARKHFVSYYVLKKSGQNKKTNQNKRQNQNKRQNQNKRRGQPVPEQEIMEKPTTSCKWCSQGVTRRGRRY
What is the function of this protein?
Involved in nuclear basic protein transition: histones are replaced by spermatid specific proteins which are themselves replaced by protamines in late spermatids.
What are the official names of this protein?
Spermatid nuclear transition protein 4, STP-4, TP-4, TP4.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YIDC_SALA4
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQTQQTTQTTTTAAGSAADQGVPASGQGKMITVKTDVLDLTINTRGGDVEQALLPAYPKELGSNEPFQLLETTPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQNELQVPMTYTDAAGNTFTKTFVFKRGDYAVNVNYSVQNTGEKPLEVSTFGQLKQSVNLPPHRDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNVSSKGGWVAMLQQYFATAWIPRNDGTNNFYTANLGNGIVAIGYKAQPVLVQPGQTGAMTSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL24_MYCSS
Sequence: MKVHKGDTVLVVSGKDKGAKGKVIQAYPTRNKVLVEGVNRIKKHTAVSSNERGASSGGIVTQEAPIHVSNVMVVDSDGNPTRIGYRVDEETGKKVRVSKRNGKDI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: HSLU_ACTP7
Sequence: MSMTPREIVSELDAHIIGQNEAKRAVAIALRNRWRRMQLPEDLRQEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIKDLTDVAVKLVKSQAVEKNRMRAQDAAEDRILDVLLPPAKDQWGNVQESDNSSTRQVFRKKLREGQLDDKEIEIDVAAQVSVEIMTPPGMEEMTSQLQSLFEGMSPNKTKKRKMKIKDALKVMVDEEAAKLVNPEELKQQAIEAVEQHGIVFIDEIDKICKKGEHSGGDVSREGVQRDLLPIIEGSTVNTKHGMVKTDHILFICSGAFQVARPSDLLPELQGRLPIRVELKSLTKEDFERILTEPNASLTLQYRELMKTEGVEIEFTKDGISKIAESAFRVNEKTENIGARRLHTVLERLMDGISFDASERSGEKIVIDEKYVQAALNDVVENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_METVS
Sequence: MTLEILLVNDDGIYSNGLLALKNVLSSEFDANVTVVAPTNQQSGIGRAISFFEPLRITKTKLSDCSEGYAVSGTPSDCVVLGIYQVLKKVPDFVISGINIGENLGTEITTSGTLGAAFEGSHHGAKAFACSLQVTADHLKFKEGESPIEFLNAANVFKKVFEKFLDSEFPCDVLNVNIPEDATLNTPVEITKLAKKMYTTHVEERIDPRSRSYYWIDGYPIMEEEDGTDVYAIRRKKHVSLTPLTLDTTIKNIELFQEIYKKKF
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DD21A_XENLA
Sequence: MPVKVYAEEMEGESMKKKKLSETPLPKIKKRKMKNGDTEDLDLEHMAESVNGEINNNNPTPKLKKKKKPAPISDLSETAEECDGEQPDPSTPTPKKVKKKKIKESKEDSDTQEEAEQSEPQTNGVKSVKKSKKNITSDDNEPAPKKRKTDTTEITTAKECEEKVLTKEEQDINQEKIDGDFSKFPLSKETIKNLQAKGVSYLFPIQSKTFHTAYSGKDVVVQARTGTGKTFSFAIPLVEKLNEDQQPLARGRAPRVIILTPTRELAIQITNEIRSITKKLKVSCFYGGTPYQQQVFAIKDGIDFLVGTPGRVRDLVQNYRLDLTTLKHVVLDEVDMMFDMGFSEQVEEILSVRYKADPEENPQTLLFSATCPDWMYNMAKKYMRKQFEKIDLIGHRSQKAATTVEHLAIECTRSQKAAVLGDLVQVYSGSHGKTIIFCDSKLEAHTLATSCGSLKQSAKSLHGDLQQKEREVVLKGFRQGTFEVLIATNVAARGLDIPEVDLVVLYSAPKEADAYVHRSGRTGRAGRTGVCISLYEPWERHYLRNVERSTGITFKRVGVPSLLNVAKSSSADAIKSLDTVPADVIEHFKEYAQELIEQKGALTAIAAALAHISGATSIKQRSLLNMEAGCDTITLKSSVPIHSLSYAWQSIKEQLGDDVDSKIHRMCLLKDSMGVCFDVRSENLESMQERWTDTKQWQFTVATELPAIQESERNFDGPRNRGFGGRGRRPFDRRNNSRNSNRGGGGRGRNRNGGFRRGR
What is the function of this protein?
RNA helicase that acts as a sensor of the transcriptional status of both RNA polymerase (Pol) I and II: promotes ribosomal RNA (rRNA) processing and transcription from polymerase II (Pol II) (By similarity).  Binds various RNAs, such as rRNAs, snoRNAs, 7SK and, at lower extent, mRNAs (By similarity).  In the nucleolus, localizes to rDNA locus, where it directly binds rRNAs and snoRNAs, and promotes rRNA transcription, processing and modification (PubMed:12851405) (Probable).  Required for rRNA 2'-O-methylation, possibly by promoting the recruitment of late-acting snoRNAs SNORD56 and SNORD58 with pre-ribosomal complexes (By similarity).  In the nucleoplasm, binds 7SK RNA and is recruited to the promoters of Pol II-transcribed genes: acts by facilitating the release of P-TEFb from inhibitory 7SK snRNP in a manner that is dependent on its helicase activity, thereby promoting transcription of its target genes (By similarity).  Required to prevent R-loop-associated DNA damage and transcription-associated genomic instability (By similarity).
What are the official names of this protein?
Nucleolar RNA helicase 2-A, DEAD box protein 21-A, Gu-alpha-A, Nucleolar RNA helicase Gu-A, xGu-1, Nucleolar RNA helicase II-A, RH II/Gu-A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm, cytosol. Mitochondrion.
Protein: LLDP_ECOL6
Sequence: MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWRGIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFRFGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEWVINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPSDAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLGWLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP
What is the function of this protein?
Uptake of L-lactate across the membrane (By similarity).  Can also transport D-lactate and glycolate (By similarity).  Seems to be driven by a proton motive force (By similarity).
What are the official names of this protein?
L-lactate permease.
What is the protein family that this protein belongs to?
Belongs to the lactate permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOK_PARP8
Sequence: MLSLAHYLVLGAILFAISIVGIFLNRRNVIIILMAIELMLLAVNTNFVAFSHYLGDVHGQIFVFFVLTVAAAEAAIGLAILVTLFRSLDTINVEDLDQLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS3_HALH5
Sequence: MGQKVNPVGLRVGVIRDWESKWYAEKDYADLLHEDIKIREYIENRLKDASVSKIEIERAANRVNITISTAKPGMVIGKGGSEVEALRKALNELTGKRVHINIFEVKQADLDAKLVAENIARQLENRISFRRAMKQAIQRTMRAGAQGIKTQVSGRLGGADIARAEHYSEGTVPLHTLRADIDYGTAEADTTYGKLGVKIWIYRGEVLPTKGKNKKEGGN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RSMH_STACT
Sequence: MFHHVSVMLRETIDELNVKKDGVYVDCTLGGAGHALYLLNQLDENGHLIAIDQDLTAIENAKEVLKDHLDQVTFVHSNFRQINQILDDLDIDKVDGIYYDLGVSSPQLDVPERGFSYHQDARLDMRMDQTQELSAYEVVNEWPYEDLVRIFYRYGEEKFSKQIARRIEKTRENEPIETTLQLVDVIKEGIPAKARRKGGHPAKRVFQAIRIAVNDELKAFEDSLEQAIERVKVHGRISVITFHSLEDRLCKQIFQEYEKGPEVPRGLPIIPEEYTPKLKRVNRKPISASEEDLAENNRARSAKLRVAEILK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_STREM
Sequence: MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSLLGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYGEDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADASIQQAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPDELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_PROM5
Sequence: MTSSKKSSDNSSSSNDLYAIAETSGQQFWFEVDRYYDIDRLNAKEKDKITIDKILLIKDKENVSIGKPYIKNAKIELEVVSHKRDKKIIVYKMRPKKKTRRKMGHRQELTRVMVKSISISKSTPKSSPKTEATKKSTSSKASKPEN
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TGT_PROM2
Sequence: MFEFEITSNCSNTKARTGIFHTPNGKVNTPKFMPVGTMATVKGISSKQLTSTGSEMILSNTFHLHLQPGEKLVKESGGIHNFMNWSKPILTDSGGYQVFSLAKLNNISDKGVEFKNPRDGSHVFLSPEKVIKIQMDLGSDVAMAFDHCPPHTANENDIEDSLQRTHSWLEKCIETHQKSNQALFGIVQGGKYPRLREYSAKFTSSFDLPGIAVGGVSVGEAVEDIHSVINYVPKFLPINKPRYLMGIGSLREISLAVANGFDIFDCVLPTRLGRHGTAFLNDERLNLRNARFKNDFSPIDKTCKCETCKSYSRAYLHHLIRNDEILGLTLISLHNIAHLLRFTNAISTAIKDNCFTNDFAPWKTSSIAHHTW
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: Y1604_LACJO
Sequence: MEMPREGDYIAIQSYKHNGTLHRNWRDTMVVKTEQNIIIGVNDRTLITEEDGRKWISREPAIVYFHRKLWFNVIAMLRPDGVAYYANLASPFILDREALKYIDYDLDIKVFPDGEKRLLDADEYAMNKKRWHYSEEIDSILRSTSFELLDWIDQKKGPFARKFVQIWYERYNQLRPDLDRSFFKGRENEERKILGT
What are the official names of this protein?
UPF0374 protein LJ_1604.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: NUOD_BURP0
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMVNEHGYVLAIEKLLGIEVPERAQYIRVLFDEITRVLNHLMWIGAHALDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPEAMPQYKASKIRNERALAKMNEARSGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGLTGPMIRGSGIAWDLRKKQPYEVYDRLDFDIPVGVNGDCYDRYLVRVEEMRQSTRIAKQCIEWLRKNPGPVITDNHKVAPPSRVGMKTNMEDLIHHFKLFTEGFHVPEGETYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALDEMARGHMIADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDUS5_MACFA
Sequence: MPFLDIQKRFGLNIDRWWTIQSAEQPYKLAPRCHAFEKEWIECAHGIGAIRAEKECKIEYDDFIECLLRQKTMRRVNAIRRQRDKLIKEGKYTPPPHHIGKGEPRP
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5, Complex I-15 kDa, CI-15 kDa, NADH-ubiquinone oxidoreductase 15 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS5 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space.
Protein: UPK3L_HUMAN
Sequence: MDNSWRLGPAIGLSAGQSQLLVSLLLLLTRVQPGTDVAAPEHISYVPQLSNDTLAGRLTLSTFTLEQPLGQFSSHNISDLDTIWLVVALSNATQSFTAPRTNQDIPAPANFSQRGYYLTLRANRVLYQTRGQLHVLRVGNDTHCQPTKIGCNHPLPGPGPYRVKFLVMNDEGPVAETKWSSDTRLQQAQALRAVPGPQSPGTVVIIAILSILLAVLLTVLLAVLIYTCFNSCRSTSLSGPEEAGSVRRYTTHLAFSTPAEGAS
What are the official names of this protein?
Uroplakin-3b-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the uroplakin-3 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NNRE_LENBN
Sequence: MTQAITVEESRELDDKTINKIGIPSLVLMERAGLKIYENMLDNKDLDLSNVLILAGTGNNGGDGLVVARLLATHGYQVSILTVGNPDHASEDHLAQARICNYYQIPKVFMNADFNKFTTLVDALFGSGLSRNVGGDFATIIDKANASTAKIHAIDIPSGLNGDTGDVMGTAIKAISTSTVAYPKVGMLKDQAKPYTGKIYVDDIGIYRGNAFENE
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: PSAA_STIHE
Sequence: MTINLPEKEAKRVQIAVDRNPVETSFQKWAKPGHFSRTLAKGPNTTTWIWNLHADAHDFDSHTSDLQDISRKVFSAHFGQLGIILIWLSGMYFHGARFSNYEAWLSDPTHIKPSAQIVWPIVGQEILNGDVGGGFQGVQITSGFFQLWRASGITSELQLYTTAVVGLVLAGAMFFAGWFHYHKAAPKLEWFQNVESMLNHHLGGLLGLGSLGWAGHQIHVSLPVNKLLDAGVDPKEIPLPHEFFLNKQLMIDLYPSFAKGLTPFFTLQWSEYSDFLTFKGGLNEVTGGLNLSDTAHHHLAIAVLFLIAGHMYRTNWGIGHSIKEILDAHKGPLTGEGHKGLYEILTTSWHAQLAINLALFGSLSIVVAHHMYSMPPYPYLATDYATQLSLFTHHCWIGGFCIVGAGAHAAIFMVRDYDPTNNYNNLLDRVLRHRDAIISHLNWVSIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWVQNTHFMAPQLTAPNALAATSATWGGDVVAVGGKVAMMPISLGTADFMVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSLSIVIFHFSWKMQSDVFGTVVNNTVSHITAGNFAQSANTINGWLRDFLWSQSSQVIQSYGSALSAYGLIFLGAHFILLTGMLDIFSGRGYWQELIESILWSHAKLKVAPTIQPRALSITQGRAVGVAHYLLGGIATTWSFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: OTSA_MYCVP
Sequence: MAPQSGPEARSGGADFVVVANRLPIDMVRRADGTTEFKRSPGGLVTALEPLLRRRHGAWIGWPGVPEDADDPNAATEPIEQDGMTLVPVRLSSEDVAEYYEGFSNATLWPLYHDVIVKPIYHREWWDRYVDVNRRFAEATAHTAAEGATVWVQDYQLQLVPKMLRMLRPDLTIGFFLHIPFPPVELFMQMPWRTEIIEGLLGADLVGFHLPGGAQNFLILARRLIGATTSRGNVGVRSRFGEVQFGFRTVKVGAFPISIDSAELDQHARSRATRQRAKEIRAELGNPRKILLGVDRLDYTKGIDVRLRAFSELLEEGRIDPEDTVLVQLATPSRERVESYVAMREDIERQVGHVNGEFGEVGHPVLHYLHRPIPREDLVAFFVAADVMLVTPLRDGMNLVAKEYVACRHDLGGALVLSEFTGAAAELRQAYLTNPHHIEGVKDAIEAALTQAPEEGRRRMRAMRRQVLAHDVDRWARSFLDALASKEPVEG
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose and in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P).  Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Probably also able to use ADP-Glc, CDP-Glc, GDP-Glc and TDP-Glc as glucosyl donors.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: MPP7_XENTR
Sequence: MPALSTGAGSDTGLYEILATLPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYYEKENPMPVIHSATALAEELAEELQSKSLNSEIRELLKLLSKPNLKALLSVHDTVAQKSYDPVLPPMPDDIDDDEDSVKIIRLVKNREPLGATIKKDEKTGAIVVARIMRGGAADRSGLIHVGDELREVNGISVEDKKPEEIIHILAQSQGAITFKIIPSIKEEPPNNDGKMFVKALFDYYPNEDKAIPCKEAGLSFRKGDILQIMSQDDATWWQAKHEGDANPRAGLIPSKQFQERRFALRKPVVSNQPQKVPNRKSSGFRRSFRLSRKDRKTNKFMYECKKSDQYDTADVPTYEEVALYQRKPNEKYRLVILVGPVGVGVNELKRKVLIGNSQHYGVTVPHTTRGKRSQENDGVEYIFISKHLFETDIHNNKFIEYGEYKNNYYGTSLDSVRSVLAKNKICLLDVQPNSLKHLRTSEFKPFVIFIKPPTIERLRETRRNAKVISGKDERGAAKPFSDEDFEEMIQSAEAMEAQYDHFFDTTIVNDDLSAAYNELRSTLERLEMEGFWVPVSWLHS
What is the function of this protein?
Acts as an important adapter that promotes epithelial cell polarity and tight junction formation.  Involved in the assembly of protein complexes at sites of cell-cell contact (By similarity).
What are the official names of this protein?
MAGUK p55 subfamily member 7.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cell junction, tight junction. Cell junction, adherens junction.
Protein: SYT_HAEIN
Sequence: MPIITLPDGSQRQFDRPVSVLEVAQDIGAGLAKATIAGRVNGERRDACYVIEQDATLEIITAKDEDGLEIIRHSCAHLLGHAIKQLFPDVKMAIGPTIENGFYYDVDLDRSLTQEDIDAIEKRMLELAKTNYDVVKKRVTWQEARDTFEKRGEPYKMAILDENIERTATPALYHHLEYIDMCRGPHVPNMRFCQHFKLQKVAGAYWRGDSKNKMLQRIYGTAWADKKQLAEYLTRLEEAAKRDHRKIGKALDLYHMQEEAPGMVFWHNDGWTIFRELETFVRTKLKQYDYQEVKGPFMMDRVLWEKTGHWQNYADLMFTTQSENREYAIKPMNCPGHVQIFNQGLKSYRDLPIRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEDQIESEVTSCIKMVYDIYSTFGFTNIAVKLSTRPENRIGSDEMWDRAEAGLAAALAHNGLEYEIQEGEGAFYGPKIEFALRDCLGREWQCGTVQLDFALPGRLDATYVAEDNSRKTPVMIHRAILGSIERFIGIITEEYAGFFPAWLAPTQAVVMNITDSQADYVQKVAKQLSDVGLRVKTDLRNEKVGFKIREHTLRRVPYMLVCGDKEIAEGKVAVRTRKGADLGTFTVEEFAEILKNQVRSRELKLLNEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_MYCSS
Sequence: MPTINQLVRKGRRDKIAKVKTAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RUVC_NITEC
Sequence: MLPSGKSIRILGIDPGLRITGFGVIEKNGSQLTYLGSGCVVTEKSGLPDRLKTILDGLNEIILQHQPEQVAVEQVFVNINPKSTLLLGQARGAAISAAVLHELSVYEYTALQIKQSVVGNGHARKEQVQEMVMRLLRLGERPRPDAADALACAICHAHGGTGLLALSVRNHLKRGGCP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.