PharMolix/UniProtQA huggingface dataset:
Protein: RS3_AGGAC
Sequence: MGQKVHPHGIRLGIVKPWSSTWFANTQDFADNLEGDFKVRQFLNKELANASVSRITIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRNAVAKIAGVPAQINIAEVKKPELDAKLVADSIASQLERRVMFRRAMKKAVQNAMRLGAKGIKVEVSGRLGGAEIARSEWYREGRVPLHTLRADIDYNTAEAHTTYGVIGVKVWIFKGEILGGMAALAQPEQQPTDKPKKVPRGKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SURE_DINSH
Sequence: MRILITNDDGINAPGLEVLAEIAAEIAGPGGEVWTVAPAFEQSGVGHCISYTQPTMIAELGPRRYAAEGSPADCVMAGLYDVMNGDAPDLILSGVNRGNNSGENALYSGTLGGAMEGALQGHKAIALSQYYGPAMATADDPFDAARRHGVAVVRKLLAADQWGGPGYGTFYNVNFPPVLAAGVKGVRAAPQGLRSHARFRVEAQLSPSGRRFLWVQGSAQNVPAEQGSDVSLNLDGYISVTPMRADLTAYDKLADLEAALA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_MYCA1
Sequence: MTVKQSQASRLGPIFEACRDDDRAALIGYLPTGYPDVPTSVQAMVALVESGCDIVEVGVPYSDPGMDGPTIARATEAALHGGVRVRDTLAAVEAISAAGGRAVVMTYWNPVLRYGVDAFARDLAAAGGYGLITPDLIPDEAGQWLAASERHGLDRIFLVAPSSTPQRLALTVEASRGFVYAASTMGVTGARDAVSHAAPELVSRVREISDIPVGVGLGVRSREQAAQIGGYADGVIVGSALVSALGDGGLTALRALTEELAAGVRQRAAAS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: AROE_OLEA2
Sequence: MTIPRIPRQLYGIIGYPLGHSMSPLLHNWGFELLGEQAAYMAFPVAPEKLAEFICCARMLPVSGLSVTIPHKQAVMPLLDAVTPRAQAAGAVNTLFYDDGKLTGDNTDVYGFLHPLDSCGTAHAAALVLGAGGAANAVLAALTARGMCNVTVTNRNGDRARILAERFGVRCVAWEERHAVDADLVVNTTPLGMAGDRQAQTPLDPAFFSSRPAGLAYDLIYNPAQTFFLASAQAAGWRVLNGLDMFVAQGAEQFRIWRGRELPFAQARALIADALASGC
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CH10_BUCTT
Sequence: MNIRPLHDRVIVKRKEVESKSAGGIVLTGSAAGKSTRGEIIAVGKGRVLENGNTQPLDVKIGDTVIFNDGYGVKVEKIDNQDMLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_LISW6
Sequence: MTNELVYEGKAKQLFKTEEAGVLRVAYKDDATALNGVRKESFAGKGELNNQITALIFSYLEEAGIRSHFIRAISETEQLVKEVSIIPLEVVVRNVIAGSLAKRLGKEEGEEIPSAIVEFYYKEDALDDPFINDDHVLYLEIATTNEMEVIRKAARSINEVLQVLFNQMNITLIDFKLEFGRDADGNILLADEISPDTCRLWDKETKQKLDKDVFRRNIGNLTDVYTEVLNRLKQVQN
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: CSN7_DROME
Sequence: MTQDMLLGNEEPSKSKETFLEKFCVLAKSSTGAALLDVIRQALEAPNVFVFGELLAEPSVLQLKDGPDSKHFETLNLFAYGTYKEYRAQPEKFIELTPAMQKKLQHLTIVSLAIKAKSIPYALLLSELEIDNVRHLEDIIIEAIYADIIHGKLFQNTRILEVDYAQGRDIPPGYTGQIVETLQAWVNSCDSVSNCIEMQIKYANAEKSKRLINKERVEQDLINLKKVLKSQTSDSDESMQIDTHGPGTSGGLGQSELRKKPSKLRNPRSAAVGLKFSK
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting.  It also promotes Ubl-dependent degradation of cyclin E (CycE) during early oogenesis.
What are the official names of this protein?
COP9 signalosome complex subunit 7, Dch7, Signalosome subunit 7.
What is the protein family that this protein belongs to?
Belongs to the CSN7/EIF3M family. CSN7 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YQGF_ECO8A
Sequence: MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNLIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVEARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F26G_SOLTO
Sequence: MTLEEKIGQMSQIDARRIGAATALEVRGFLISDSQGIDRHNLIPMSRIDDAVSRKSLVLLK
What is the function of this protein?
Beta-glucosidase highly specific for the cleavage of C-26-bound glucose moiety of furostanol glycosides torvosides A and H.  Hydrolyzes only p-nitrophenyl-beta-glucoside, but not p-nitrophenyl-beta-D-fucoside, p-nitrophenyl-beta-L-fucoside, p-nitrophenyl-beta-D-xyloside, p-nitrophenyl-beta-D-galactoside, p-nitrophenyl-beta-D-NAc-glucosamine, p-nitrophenyl-beta-D-mannoside or any of the p-nitrophenyl-alpha-glycosides tested.
What are the official names of this protein?
Furostanol glycoside 26-O-beta-glucosidase, Torvosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
Protein: BT3A3_PONAB
Sequence: MKMASSLACLLLNFHVSVFLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELRWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVEVKGYENGGIHLECRSTGWYPQPQIKWSDAKGENIPAVEAPVVADGVGLYAVAASVIMRGGSGGGVSCIIRNSLLGLEKTASISIADPFFTSAQPWIAALAGTLPISLLLLAGASYFLWRQQKEKIALSRETERERELKEMGYAATKQEISLREKLQDELKWRKIRYMARGEKSLAYHEWKMALFKPADVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWRYCVLGCENFTSGRHYWEVEVGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGPTDGNKYRALTEPRTNLKLPEPPRKVGIFLDYETGEISFYNAMDGSHIYTFPHTSFSEPVYPVFRILTLEPTALTICPTPKEVDRSPNPDLVLDHSLETPVTPALANESGEPQAEVTSLLLPANAGAEGVSPSTTTSQNHKPQACTEALY
What are the official names of this protein?
Butyrophilin subfamily 3 member A3.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. BTN/MOG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ZDHC6_DICDI
Sequence: MIDHNNIIIGNSINSKTFSLIESVKNGKLKECIGYLEKIRLQNPSLDLGEIINSGDDCGNTALHWACYKKWYDIVKYLLSMGADPNIANTDELQTPFQWACIGGDLHIVKYVLNNGGDPHLQDKRGYNSLIHATQYNEISVVRYLLDKGGVNVDSPDFLQKTSLHWAAYQGHTQLLLFLVNKGADINALDSLGRSPLHWAAFKGNSDPIKALCDFGSKTMEKDSNNQSPSDICSSQNHNYLAHFIKTFNYHPFRKVGPLLYNIFWIIFAILLQLYFGFIFYHFTLIPALILFGASLTCCKLFIEPITLSNSPNPLLPTWMITSFTVSFVYYVRYVVPAFPNIILTHTITLFVYSSYYYCAFKLFFSDPGTVSSSTTSQDSKDFINAVEKELEIPEVCSTCLINKPIRAKHCRTCKRCVARFDHHCAWINNCVGVNNNLLFIILLCLFSLAYIISVTFNFKLMSIDENSPLYSEGKMEWWTYHYSTYKGLILFTIYKSFIMAWLARLLYVQITGVINNVTMFELMKPPKGSKKKCCNHAPQDQNNNNNNNNTTTNNSSSSSSSNNNSTGTNNDNNNNNNLGTSSNESGQSNCNIDQHNDHDGQSSEPLLNEVSIQIRSENGVEEDDDDENNKNPSNKSFNKNSRDLDPTQTNFRDSILIPKRTNNNENPYDKGSRENIREFLYDTSKWFRTTTFSNKNF
What are the official names of this protein?
Putative ZDHHC-type palmitoyltransferase 6, Zinc finger DHHC domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ANSA_STRCZ
Sequence: AAGNPSETGGAVATYSTAVGSFLDGTVKVVATGGASRVPGNCGTAAVLECDNPESFDGTRAWGDLSADQGTGEDAPPETASLIFAVN
What are the official names of this protein?
Antibacterial substance A.
Protein: PRS37_HUMAN
Sequence: MKYVFYLGVLAGTFFFADSSVQKEDPAPYLVYLKSHFNPCVGVLIKPSWVLAPAHCYLPNLKVMLGNFKSRVRDGTEQTINPIQIVRYWNYSHSAPQDDLMLIKLAKPAMLNPKVQPLTLATTNVRPGTVCLLSGLDWSQENSGRHPDLRQNLEAPVMSDRECQKTEQGKSHRNSLCVKFVKVFSRIFGEVAVATVICKDKLQGIEVGHFMGGDVGIYTNVYKYVSWIENTAKDK
What is the function of this protein?
Plays a role in male fertility (By similarity).  May have a role in sperm migration or binding to zona-intact eggs (By similarity).  Involved in the activation of the proacrosin/acrosin system (PubMed:27649891).
What are the official names of this protein?
Probable inactive serine protease 37, Probable inactive trypsin-X2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted.
Protein: Y958_LEIXX
Sequence: MTEIRYVRLLTLVLASSVLLAGCSSAVPTTPVRSATPSAAATPTATPVVPPTVNPAATASLHAAARSGDAEAVRSALAAGAAIEDRGEGGRTPLVEAAKGNHVEAARALIEAGADVNAKDDIQDSAYLYAGAEGYLEILRMTLTTGADVNAKNRFNGTALIPASEHAHTEVVRMLIAAGVDLDHVNTPGWTAMQEAIVLGNGGAGAQDVVRQLLAAGANPDIRDSRGRTSLCNATRLGFGAIASQLRAAGATGC
What are the official names of this protein?
Putative ankyrin-containing lipoprotein Lxx09580.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CAZA2_ATEGE
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAIESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: CHEL_CAUVC
Sequence: MSVLSALTSLTPRIDAAAITAKQLVMSAEEKAKRAQIADTAKTFEASFLSVMTQQMFEGVKTSAPFGGGNGEAMFKSILTDAMSKEISKAGGVGLASTIQREMLKLQGLKE
What are the official names of this protein?
Chemotactic signal-response protein CheL.
Protein: NU1M_RHIUN
Sequence: MFTINILLLIIPILLAVAFLTLVERKVLGYMQLRKGPNIVGPYGLLQPIADAIKLFTKEPLQPSTSSTSMFIIAPIMALTLALTMWVPLPMPHPLINMNLGVLFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMNGSFTLSTLITTQEHLWLIFPSWPLTMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIIMMNAFTTILFLGAFHNPYMPELYTVNFTIKTLLLTISFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVSLPITMSSIPPQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KAD2_PICST
Sequence: MTVEDLKATVAKLQERIQYLEKKAGLVPDVPKSVRMVLIGPPGAGKGTQAPNLKEKFCACHLATGDMLRAQVAAKTALGVEAKKIMDQGGLVSDEIMVNMIKSELENNKECANGFILDGFPRTIPQAEKLDSMLVDRKTPLENAIELKIDDELLVARITGRLVHPASGRSYHKLFNPPKKNMIDDITGEPLVQRSDDNEAALKKRLVTYHKQTEPIVDYYRKTGIWSGIDASQKPATVWTDILKCLGQK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: HEM6_VIBCM
Sequence: MKSNIDKQAVKNFLLQLQDQICQQLEAADGQAQFIEDAWQREPGEKLGGGGRTRVMRDGAVFEQGGVNFSHVFGEQMPGSATAHRPELAGRRFEAMGVSLVMHPKNPYVPTSHANVRYFIAEKEGEDPIWWFGGGFDLTPFYPFVEDCQLWHQTAKNLCAPFGAEIYNEHKAWCDRYFYLPHRNETRGIGGLFFDDLNEWPFEQCFAYMQAVGEGYTQAYVPIVEKRKNTPFTERERQFQLYRRGRYVEFNLVLDRGTLFGLQTGGRTESILMSMPPLARWEYAYQPESGTPEAQLSEFLVPREW
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUR1_MYCFO
Sequence: MADGLDFTGMLRSAGLRITRPRLAVLNAVKEHPHAETDHVIRAVRVQLPDVSHQTVYDXLNALTAAGLVRRIQPTGSVARYETRVNDNHHHVVCRSCGAIADVDCAVGDAPCLTAADDNGFDIDEAEVIYWASALTARDLRVLDDSPVAHQMKGKAMPPNT
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein 1, Ferric uptake regulator 1.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_POLNA
Sequence: MPKMKTKSGAKKRFRVRPGGTVKRGQAFKRHILTKKTTKNKRQLRGSVAVHETNMGHMAQMLPGRGI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: UGPC_BURPS
Sequence: MAALSLKGVRKSYGGAQYVLHGIDVDIADGEFVVLVGPSGCGKSTLLRMIAGLETVTEGEIAIGGRVVNALEPKDRDIAMVFQNYALYPHMTVAQNMGYGLKIRGVERALIDARVQAAAQILELGPLLARRPRELSGGQRQRVAMGRAIVREPSVFLFDEPLSNLDAKLRVQMRLEIQRLHARLATTSVYVTHDQIEAMTLAQRVIVMNRGYAEQIGAPVDVYEKPATTFVASFIGSPAMNLLHGRLSEDGAAFDVADGPRLPVAGAAGAGRGIAPGREWILGVRPEHMTPQPGEAFATLAVDSCELLGADNLAHGRWGAHDVAVRLPHAMRPTRGETLPVALPARHLHFFDPATGKRAG
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UPP_THEM4
Sequence: MKINVVDHPLIKHKLTLMRKKDTGPKEFRELLKEITLLIAYEATRHIETFETEIETPLEKTKGHFINDKDVVIIPILRAGLGMSDGILQLLPNASVGHIGIYRDPKTLEAVEYYAKFPKITDNSIVFVLDPMLATGVSSIKALEIVKKNGAKNIILVTLIASPEGTEKVNIEHPDVIIYTASLDKKLNSKGYILPGLGDAGDRLFRTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RL23B_SCHPO
Sequence: MSRGRGAASGTKYRMTLGLPVQAIMNCADNSGAKNLYIVSVFGTGARLNRLPAASCGDMVLATVKKGKPDLRKKIMPAIVVRQRKAWRRKDGVYLYFEDNAGVIVNPKGEMKGSAITGPVAKECADLWPRIASNAGTVV
What are the official names of this protein?
60S ribosomal protein L23-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: U520_HUMAN
Sequence: MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTKPQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKITDYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTLSANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFLYQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGSHFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQVLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFEPLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVESVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQLEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATGAHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD
What is the function of this protein?
Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome (PubMed:35241646).  Plays a role in pre-mRNA splicing as a core component of precatalytic, catalytic and postcatalytic spliceosomal complexes (PubMed:28502770, PubMed:28781166, PubMed:29361316, PubMed:30315277, PubMed:29360106, PubMed:29301961, PubMed:30728453, PubMed:30705154).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).  Involved in spliceosome assembly, activation and disassembly.  Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome.
What are the official names of this protein?
U5 small nuclear ribonucleoprotein 200 kDa helicase, Activating signal cointegrator 1 complex subunit 3-like 1, BRR2 homolog, U5 snRNP-specific 200 kDa protein, U5-200KD.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
Protein: PAND_BACC2
Sequence: MFRTMMRAKLHRATVTEANLNYVGSITIDEDLMDAVNIVENEKVQIVNNNNGARLETYVIKGERGSGVVCLNGAAARLVQPGDKVIIICYGLVTEEEVHKQEPKIAVLDDNNQIIEMLGAEKAGTIL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_KORVE
Sequence: MDKFVIRGGTPLLGNVRVSGAKNAALPAMAAALLTEEPVILENIPQVRDIITERNLLQAMGAEVELGYGRAHHRTTLCCRNLVNPEASYELVKTMRASTLVLGPLVARTGEARVSLPGGCAIGARPIDLHIKGLEKLGAEITQEHGYIKAKATRLKGNHIVFEKITVTGTEDLLMAATLADGETVMENCAREPEVTDLAHLLVKMGAKIEGIGTSTLKITGVEKLHGAKHRIIPDRIEAGTFIIAGALTGGDLMVQNCDPSHLGALLAKLEENGVKIRSNGDSVRVMSEGTLKPGDASTEEYPGFPTDMQAQYMALATQCEGASVVVENIFENRFMHAQELVRMGANIKIEGRRAIVRGKTPLSGAAVLASDLRASASLVLAALVAEGETIIDRVYHIDRGYEHIEEKLRGLGAEIKRIGELFPKKASPVAVS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_FUSNN
Sequence: MKKEVIIALDFPTLEKTLEFLDKFKEEKLFVKVGMELYLQNGPIVIDEIKKRGHKIFLDLKLHDIPNTVYSAVKGLAKFNIDILTVHAAGGSEMLKGAKRAMTEAGVNTKVIAITQLTSTSEEDMRKEQNIQTSIEESVLNYARLAKESGVDGVVSSVLETKKIREQSGEEFIIINPGIRLAEDSKGDQKRVATPIDANRDGASYIVVGRSITGNENPEERYRLIKNMFEMGDKYVE
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CYB_AKOMI
Sequence: MKILRKNHPLLKIVNHSFIDLPTPSNISSWWNFGSLLGACLMIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYALSETWNIGIILFLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALALVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDLLGIFLLLMALMILALFFPDLLGDPDNYTPANPLNTPAHIXPXXXXXFAYAILRSIPNKLGGVLALILSILILATFPLLNTSKQHGLIXRPVTQTIYWIFIANLLVLTWIGGQPVEYPFTMIGQIASISYFTIIIILMPLSNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NEF_HV2UC
Sequence: MGSAGSKKQSKQQRGLRERLLRTQEEPYGKLSEGQRKQSSRSPGGSDKDLNSPSCEGRNAPRAEGGGQQDTDDSDEDNEVGVYVRPNRPLRSMTYKMAIDMSHFIKEKGGLEGIYYSERRHRILDTYLENEEGIVSGWQNYTYGPGIRYPRTFGWLWKLVPVDIPEEERGAETSCLVHPAQISSWDDIHGETLAWRFDPLLAHDYVAFNRYPEEFGYQSGLPEKE
What is the function of this protein?
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Associates with the inner plasma membrane through its N-terminal domain.