PharMolix/UniProtQA huggingface dataset:
Protein: NAGZ_YERPB
Sequence: MGPVMLDVASYELDAEEREILKHPLVGGLILFSRNFHDAEQLRELVRQIRAASHERLVVAVDQEGGRVQRFRDGFTRLPAAQSFAAINDAATAAQLAQEAGWLMAAEMMAMDIDISFAPVLDIGHVSAAIGERSFHSDPQQARIMAECFIRGMHSAGMKTTGKHFPGHGAVTADSHKETPHDNRPLAEILTHDMVIFRELIQRKLLDAIMPAHVIYTEADARPASGSAYWLQEILRQELGFEGIIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRQGAVSVLDNLSPIKADQLTRLYHSGQFDRQTLMASSRWQQANKALTALSERWDAHKQTLGQ
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA_WOLSU
Sequence: MHEYSIVTALLELCENHAKSNKAKKVTKVVVALGERSGVEPQLLESAFEVFKLDSVCAESELVIETKPMKFRCRSCGAEFLPKGIDFGSCEVCKAPNPELVGGKEMHLQSLEMEAEDEG
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: LPXD_YERPN
Sequence: MPSIRLADLAQQLDAQVHGDGDLVITGIASMHSAQPEQITFLSNSRYREQLASCNAGAVVLTEADLPFCKVAALVVENPYFTYARMAQIMDTTPQPAQDIAPSAVISPQATLGEGVSVGANAVIESGVVLGDNVVIGAGCFIGKNTHIGAGSRLWANVSIYHEVVIGQNCLIQSGTVIGADGFGYANDRGNWVKIPQLGSVHIGDRVEIGACTTIDRGALDNTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKVGRYCMIGGASVINGHMEICDKVTITGMGMVMRPITEPGLYSSGIPLQPNKMWRKTAALVMNIDGINKRLKAVERKIDKE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, UDP-3-O-(3-OHC14)-GlcN N-acyltransferase, UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RL10_MYCTO
Sequence: MARADKATAVADIAAQFKESTATLITEYRGLTVANLAELRRSLTGSATYAVAKNTLIKRAASEAGIEGLDELFVGPTAIAFVTGEPVDAAKAIKTFAKEHKALVIKGGYMDGHPLTVAEVERIADLESREVLLAKLAGAMKGNLAKAAGLFNAPASQLARLAAALQEKKACPGPDSAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: VAP12_ARATH
Sequence: MSNELLTIDPVDLQFPFELKKQISCSLYLGNKTDNYVAFKVKTTNPKKYCVRPNTGVVHPRSSSEVLVTMQAQKEAPADLQCKDKFLLQCVVASPGATPKDVTHEMFSKEAGHRVEETKLRVVYVAPPRPPSPVREGSEEGSSPRASVSDNGNASDFTAAPRFSADRVDAQDNSSEARALVTKLTEEKNSAVQLNNRLQQELDQLRRESKRSKSGGIPFMYVLLVGLIGLILGYIMKRT
What is the function of this protein?
Vesicle-associated protein that binds the oxysterol-binding protein ORP3A and allows its targeting to the ER.
What are the official names of this protein?
Vesicle-associated protein 1-2, Plant VAP homolog 12, AtPVA12, VAMP-associated protein 1-2.
What is the protein family that this protein belongs to?
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Protein: RNPA_ECO55
Sequence: MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: TPX_STRPN
Sequence: MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKKKVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIMLSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAAKAL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: CATA4_SOYBN
Sequence: MDPYKHRPSSAFNSPFWTTNSGAPIWNNNSSLTVGARGPILLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNLPVFFVRDGMKFPDMVHALKPNPKNHIQENWRILDFFSHFPESLHMFTFLFDDLGVPQDYRHMDGFGVNTYTLINKAGKAVYVKFHWKTTSGIKCLLEEEAIKVGGANHSHATQDLHDSIAAGNYPEWKLFVQTIDPEHEDKFDFDPLDVTKTWPEDIIPLQPVGRLVLNKNIDNFFAENEQLAFCPAIVVPGVYYSDDKMLQTRIFSYADSQRHRLGPNYLQLPANAPKCAHHNNHHEGFMNFIHRDEEVNYFPSRYDPVRHAERFPIPPAICSGRREKCGIEKENNFKQPGERYRSWAPDRQDRFARRWVDALSDPRVTHEIRSVWISYWSQADRSLGQKIASHLSTRPNI
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase-4.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: ACPS_GEOSM
Sequence: MIYGTGVDIVEIARFEKFLQQGNDALFDRIFTPSEIEYCSSKKHSAQHYALRFAAKESFLKALGTGLRDGISWKDMEVVNDQLGKPELKLYRRAEELFRQAGLGACFLSLSHDAGCAVAMVVLER
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_BURA4
Sequence: MSTWLLPENIADVLPSEARKIEELRRRLLDRFRSYGYEMVMPPLLEYLESLLTSGGADLRLRTFKLVDQLSGRTLGLRADITPQVARIDAHLLNRQGVTRLCYAGHVMHTRPRGLHATREQIQIGAEIYGHAGLEADLEIQQLMLDALHLAGLSRIRLDLCHAGVLAALLARDPQAAERGESLYDALSGKDVPLLNELTDDLGADTRAALCALPHLYGDASVLDEARARLPVLPEITRALDDLAQLAAQAKGVEVAIDLADLRGYAYHSGAMFTAYIDGVPNAIARGGRYDHVGQAYGRARPATGFSLDLRELARISPIEARGTAILAPWAQDDALGAAVAALRDAGEVVIQALPGHDHVLDEFACDRSLVERNGAWVVEPR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH_CLOB1
Sequence: MIKKRNTTKISVIGAGSVGATTAYALMLSGVATEIVLVDVNKSKTEGEAMDLSHGADFVKPVNILSGDYKDTEGSDIVVITAGAAQKVGETRLQLINKNINIFKSIIPQVVKYNKDAILLVVSNPVDVLSYVTYKLSGFPKERVIGSGTVLDTSRLKHEIGKRYKIDPRNVNTYIMGEHGDSEIATWSVTNIQNIKIDEYANKENLEYNDNFRKEVYENVKNAAYEVINRKGATFYAIALAVTRIVKAILGDEKTILPVSTLVENYYGIKDVYLGMPCIVGGSGIEKALSIDLNKTEASKLVKSAETLKNTLNNASCL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTQ_ECOLI
Sequence: MNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTALPTALKMVGQTXQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAVATQDGPQIDFSADMERQKMSAEGLMGPFALNDPAAGTTGPWYTNGTFGLTAGWHLDIWGKNRAEVTARLGTVKARAAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQNTIIATDRQLYQNGITSSVEGVETDINASKTRQQLNDVAGKMKIIEARLSALTNNQTKSLKLKPVALPKVASQLPDELGYSLLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQDALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIAKAESNLSIASYNKAVVEAVNDVARAASQVQTLAEKNQHQAQIERDALRVVGLAQARFNAGIIAGSRVSEARIPALRERANGLLLQGQWLDASIQLTGALGGGYKR
What is the function of this protein?
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
What are the official names of this protein?
Putative multidrug resistance outer membrane protein MdtQ.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: INP1_ORYSJ
Sequence: MPRPPPPPPPGRGAPGARRPMREFFAAWLSTLRSPLLPLLRRALSSSSSSSSGGWDDPLSSAAAAVEAHFQAHWSALDAAARQDPAQAVSAGDWRSPLELPFLWVGDLHPSLVTSLLRSLSPSPRLLAATDRVDRRIRAAVPSISDRLRRVQEAFISAEVSGAADVEAFLEELKDVALDANRLRRGVLSELVAAAGGYQAALFLEALSRFVLSMHDPEVLRRFDQCRASPGS
What is the function of this protein?
Required for pollen aperture formation, male fertility and LECRKS7/DAF1 function (PubMed:32284546).  Seems to be involved in operculum protrusion (PubMed:32284546).  Participates in the modification of plasma membrane at future aperture sites, possibly by creating close contact between the plasma membrane and callose wall to prevent primexine formation and sporopollenin deposition (PubMed:32284546).
What are the official names of this protein?
Protein INAPERTURATE POLLEN 1 homolog, OsINP1.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes uniformly in the cytoplasm of microspore mother cells (MMCs) during meiosis, in dyads and in the early tetrad stage. In the late tetrad stage, starts to move to distal poles of the tetrad, concentrating into prominent spots. Finally, localizes specifically at the site that marks the future aperture.
Protein: ARCA_OENOB
Sequence: MLTEKSPIHVNSEIGRLKTVILHRPGKEIENLTPDTMGPLLFDDIPYLLLAQKEHDNFADTLRKKGVEVLYLERLVVQALETDEQVKAFFIDKMIAESGFKSGTIHAQLQKFLVGLPTNEMVDKIMAGVRFDEIELASKDLQNFSFDRTRPFLMAPMPNLYFTRDPSASIGDGLTINRMTFKARRRESMFTELVINHHPRFANKNINVWRDRNHVARLEGGDELVLSDHVLAIGLSQRTSSEAIKDVAKNLFAGSNYDTVIAIQIPQTHATMHLDTVFTMVNFDQFTVHPMILNNKGELPILVMHKDKQNQIKIESSNNLKTVLKEQLGLNELDLISTGDGDPIISAREQWNDGSNTLAIAPGSVVTYDRNYVSNEALRKHGIQVSEVPSSEISRGRGGPRCMSMPIYREDIEK
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTER_CHICK
Sequence: MADPRRPARVTRYKPPTTESNPALEDPTPDYMNLLGMVFSMCGLMLKLKWCAWIAVYCSFISFANSRSSEDTKQMMSSFMLSISAVVMSYLQNPQPMSPPW
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (By similarity).  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity).
What are the official names of this protein?
PAT complex subunit Asterix, Protein WDR83OS homolog, Protein associated with the ER translocon of 10kDa, PAT-10, PAT10.
What is the protein family that this protein belongs to?
Belongs to the Asterix family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CXXS1_ARATH
Sequence: MARVVKIDSAESWNFYVSQAKNQNCPIVAHFTALWCIPSVFMNSFFEELAFNYKDALFLIVDVDEVKEVASQLEVKAMPTFLFLKDGNAMDKLVGANPDEIKKRVDGFVQSSRVVHIA
What is the function of this protein?
Possesses low disulfide reductase activity, but efficient protein disulfide isomerase activity.  Does not possess deglutathionylation activity.
What are the official names of this protein?
Thioredoxin-like protein CXXS1, AtCXXS1, Mono-cysteine thioredoxin 1.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MECA_STAAW
Sequence: MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKNEDMMNMSDDDATDQFDEQVQELLAQTLEGEDQLEELFEQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHSNPITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: MNME_VIBC3
Sequence: MTTDTIVAQATALGRGGVGIIRVSGPLAAHVAQTVTGRTLRPRYAEYLPFTDEDGQQLDQGIALFFPNPHSFTGEDVLELQGHGGPVVMDMLIRRILQIKGVRPARPGEFSERAFLNDKMDLTQAEAIADLIDASSEQAAKSALQSLQGEFSKRIHTLVESLIHLRIYVEAAIDFPEEEIDFLADGKVSADLQTIIDNLAAVRREANQGAIMREGMKVVIAGRPNAGKSSLLNALSGKESAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDASDAVEKIGIERAWEEIRQADRVLFMVDGTTTEATDPQDIWPDFVDKLPENIGITVIRNKADQTGEPLGICHVNQPTLIRLSAKTGQGVDALRQHLKECMGFSGNQEGGFMARRRHLDALERAAEHLAIGQQQLEGYMAGEILAEELRIAQQHLNEITGEFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCSF_ECO57
Sequence: MTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPRYVKPAGTLRRTEKARATKK
What are the official names of this protein?
Cellulose biosynthesis protein BcsF.
What is the protein family that this protein belongs to?
Belongs to the BcsF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CSGB_SALTI
Sequence: MKNKLLFMMLTILGAPGIATATNYDLARSEYNFAVNELSKSSFNQAAIIGQVGTDNSARVRQEGSKLLSVISQEGENNRAKVDQAGNYNFAYIEQTGNANDASISQSAYGNSAAIIQKGSGNKANITQYGTQKTAVVVQKQSHMAIRVTQR
What is the function of this protein?
Curlin is the structural subunit of the curli.  Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius.  Curli can bind to fibronectin.  The minor subunit is the nucleation component of curlin monomers.
What are the official names of this protein?
Minor curlin subunit.
What is the protein family that this protein belongs to?
Belongs to the CsgA/CsgB family.
What are the subcellular locations of this protein?
Fimbrium. Note=Part of the curli surface structure.
Protein: GOSR1_CAEBR
Sequence: MSETWEALRKKARSTENSIDVKLVSLNKLTASSHGGFDIDEKTVSSRQTTFRTVTTEIEGLIEQLTNINDDMNDVAGAQSSASWASNPAIQHTLRRHREILRDYGSEYRRARDNVDQVLQRELLLSSSNNESRNPAVNNRARGYDMYLKENDHINACDRLLDEQIEMAMSTKENVARQGINLRGISNRLHYITKKYPAINNLMQKIKTKKQKNTMILAGVISACLIFTIFWIIN
What is the function of this protein?
Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport.  It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.  Cooperates with ykt-6 for proper expression of Golgi-resident proteins.  Required along with ykt-6 for normal embryonic development, seam cell division or differentiation, and ray formation (By similarity).
What are the official names of this protein?
Golgi SNAP receptor complex member 1, 28 kDa Golgi SNARE protein, GOS-28.
What is the protein family that this protein belongs to?
Belongs to the GOSR1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type IV membrane protein.
Protein: BCR_RAT
Sequence: MVDSVGFAEAWRAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQPPDGAAEPRASAPRLPPAPADGADPAPVEESEARPDGEGSPSKGRPATARRPAAAAPADRDDRGPPTSVAALRSNFEKIRKGPAQPGSADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQQSAGQGLGEAPRPHYRGRSSESSCGLDGDYEDAELNPRFLKDNLINANGGNRPPWPPLEYQPYQSIYVGGMMVEGEGKSPLLRSQSTSEQEKRLTWPRRSYSPRSFEDSGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCQKRHRQCQVVVSEATIVGVRKTGQIWPSDGDSTFQGEADSSFGTPPGYGCAADQAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSPASGALEPTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMETAEKCCQANAQFAEISENLRARSNKDVKDSTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPSSHPDHSLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHIFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEALPNIPLVPDEELDALKIKISQIKSDIQREKRANKGSKVMERLRKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRESIREQQKKCFKSFSLTSVELQMLTNSCVKLQTVHHIPLTINKEDDESPGLYGFLHAIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTTEPNWNEEFEIELEGSQTLRILCYEKCYNKMKMAKEDGESADKLMGKGQVQLDPQTLQDRDWQRTVIDMNGIEVKLSVKFTSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKETVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV
What is the function of this protein?
Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins.  The C-terminus is a GTPase-activating protein (GAP) domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42.  Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form.  The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1.  Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form.  The amino terminus contains an intrinsic kinase activity (By similarity).  Functions as an important negative regulator of neuronal RAC1 activity (By similarity).  Regulates macrophage functions such as CSF1-directed motility and phagocytosis through the modulation of RAC1 activity.  Plays a major role as a RHOA GEF in keratinocytes being involved in focal adhesion formation and keratinocyte differentiation (By similarity).
What are the official names of this protein?
Breakpoint cluster region protein.
What are the subcellular locations of this protein?
Postsynaptic density. Cell projection, dendritic spine. Cell projection, axon. Synapse.
Protein: CAPP_STRPG
Sequence: MPLKKLESSNNQAIIAEEVALLKEMLENITRRMIGDDAFTVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVDLAYEINYQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTILELTTHIHKLLRKYRDAKAGVISLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVMQYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCLSATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRRAFHYIQSRLKQTQIQLTNQPAARMSSSVGLSTSAWSSPASLENPILAYDSPVDFKADLKAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGANIVDDYSSLSETEKCDVLVQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGEEVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAAYLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKITFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEMLISASINRMVTQMITDPNEIDSFREIMDSIVADSNIIYRKLVFDNPHFYDYFFEASPIKEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQGNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEWQLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDEKLIHTTINGIATGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: RL17_AZOVD
Sequence: MRHRKSGRHLSRTSAHRKAMFQNMAVSLFEHELIKTTLPKAKELRRVAEPLITLAKEDSVANRRLAFDRTRSKAAVGKLFNDLGKRYANRPGGYLRILKCGFRAGDNAPMAYVELVDRPVDGEALVGAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RS4_RHIME
Sequence: MSKRESSKYKIDRRMGENIWGRPKSPVNRREYGPGQHGQRRKSKLSDFGVQLRAKQKLKGYYGDIREKQFRAIFAEASRRKGDTPENLVGLLESRLDAIVYRAKFVPTVFAARQFVNHGHVKVNGVRVNIGSYRCKPGDVIEVKEKSKQLVTVLEAVQLAERDVPDYIEADHNKMVATFVRVPALSDVPYPVVMEPHLVVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ATPB_ACOCL
Sequence: MRITPTTSGSAVPSLDEKNLGRIVQIIGPVLDVAFPPGKMPNIYNALVVKGRDTAGQPINVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAALSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEEKIEESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MURA_PSE14
Sequence: MDKLIITGGVRLDGEIRISGAKNSALPILAATLLADGPVTVQNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAIIDVEGGYIKAKAPEGGLRGANFFFDTVSVTGTENIMMAASLANGRSVLQNAAREPEVVDLANFLIAMGAKIHGAGTDTITIDGVKRLGPATYKVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLLKLQEAGAEVTTGEDWIELNMHGKRPKAVNVRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGTEVLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOTA_HELPY
Sequence: MDLSTILGLVLAVASISLGDILEDGNPLHIIHLSSVIIIVPTSLFAAMTGTHARYVKAAYKEIKIVFLNPKINLNETIKNLVELATLARKDGVLSLEGRVAQIEDDFTRNGLSMIIDGKDLKSVKESLEISIEEMEEYYHGAAHYWETAGETAPTMGLVGAVMGLMLALQKLDNPAEMAAGIAGAFTATVTGIMCSYAIFGPFGHKLKAKSKDIIKEKTVLLEGILGIANGENPRDLENKLLNYIAPGEPKKSQFEG
What is the function of this protein?
MotA and MotB comprise the stator element of the flagellar motor complex.  Required for rotation of the flagellar motor.  Probable transmembrane proton channel (By similarity).
What are the official names of this protein?
Motility protein A, Chemotaxis protein MotA.
What is the protein family that this protein belongs to?
Belongs to the MotA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.