PharMolix/UniProtQA huggingface dataset:
Protein: HXB1B_DANRE
Sequence: MNSYLDYTIYNRGSNTYSSKVGCFPVEQEYLPSACASTNSYIPEGRPVGGNTFTSAPHETHGTSYAQIQSQPFHLNVDMGKTGHSNFCKQTRPPHSDYGHQHVLTQADDHMRLQSPGFSVVNMGANIGTYSESNCRPGSVSASHYQSYAYGEPEPHGYGSFSKYQVSPDSDSDSKTNIKQAPTFDWMKVKRNPPKTVKVAEYGIHGQQNIIRTNFTTKQLTELEKEFHFNKYLTRARRVEVAATLELNETQVKIWFQNRRMKQKKREKEGTAPVIKRVTLCSSGQNADHSTSSSPGASPTSDSSTAI
What is the function of this protein?
Sequence-specific transcription factor.  Part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Acts on the anterior body structures.  Seems to act in the maintenance and/or generation of hindbrain segments.
What are the official names of this protein?
Homeobox protein Hox-B1b, Homeobox protein Hox-A1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Labial subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NLPI_ECOLI
Sequence: MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALLELSLLGQDQDDLAESDQQ
What is the function of this protein?
May be involved in cell division.  May play a role in bacterial septation or regulation of cell wall degradation during cell division.  Negatively controls the production of extracellular DNA (eDNA).
What are the official names of this protein?
Lipoprotein NlpI.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CDSA_BRUSU
Sequence: MSNLQTRIITAIVLGTITLWLTWVGGVGFTLFSIAIGLAMFYEWTELSATRQTAFSRLFGWAWLIVTGILLILDRGALLTIGFLVAGCAILLVTQWKSGRGWPAAGLFYAGFSALSLSLLRGDEPFGFTTIVFLFAVVWSTDIAAYFNGRALGGPKLAPRFSPNKTWSGAIGGAAAAVAGGLLVASLVAAPGGWGVPVLALLLSIVSQIGDLAESWVKRQFGAKDSGRLLPGHGGVLDRVDGLVAAAALLYLFGAIFAEPDVPSAIFFSF
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ECCD4_MYCTU
Sequence: MPTSDPGLRRVTVHAGAQAVDLTLPAAVPVATLIPSIVDILGDRGASPATAARYQLSALGAPALPNATTLAQCGIRDGAVLVLHKSSAQPPTPRCDDVAEAVAAALDTTARPQCQRTTRLSGALAASCITAGGGLMLVRNALGTNVTRYSDATAGVVAAAGLAALLFAVIACRTYRDPIAGLTLSVIATIFGAVAGLLAVPGVPGVHSVLVAAMAAAATSVLAMRITGCGGITLTAVACCAVVVAAATLVGAITAAPVPAIGSLATLASFGLLEVSARMAVLLAGLSPRLPPALNPDDADALPTTDRLTTRANRADAWLTSLLAAFAASATIGAIGTAVATHGIHRSSMGGIALAAVTGALLLLRARSADTRRSLVFAICGITTVATAFTVAADRALEHGPWIAALTAMLAAVAMFLGFVAPALSLSPVTYRTIELLECLALIAMVPLTAWLCGAYSAVRHLDLTWT
What are the official names of this protein?
ESX-4 secretion system protein eccD4, ESX conserved component D4, Type VII secretion system protein eccD4, T7SS protein eccD4.
What is the protein family that this protein belongs to?
Belongs to the EccD/Snm4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AKA11_HUMAN
Sequence: MATFRNNHMKTKASVRKSFSEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFLGFNEETDAAHIQDLAAVSLELPDILNSLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPTSPRLRIDFIFSLLSKYATGIRYTLDTFLHQKHQLETTDEDDDDTNQSVSSIEDDFVTAFEHLEEEETSKPYNDGMNITVLRSQCDAASQTVTGHHLETHDLKILISSGQQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKTFFSSSPAYSSESECSSPSPVIFLDEEGYQKSLKAKLELPKIPVMKDDIEDSDSEVSEFFDSFDQFDELEQTLETCLFNKDPVIGKSSQRKGHKHGKSCMNPQKFKFDRPALPANVRKPTPRKPESPYGNLCDAPDSPRPVKASREDSGLFSPIRSSAFSPLGGCTPAECFCQTDIGGDRIHENHDSVYYTYEDYAKSISCEVLGSVLRTHHTNTLSNINSIKHGENKTVTFKHGNLDQKNKSKNKSLMIKDSIQKFAADLVEKSFGSAFKDLQKGVSSCTNALYHLAIKLTSSVLQMAFDELRRQRAFSLKERAISGLANFLVSEALSNALKDLQYVKKQIFTNTVARFAADLAEELVFEGIMEVCQFSYPQTPASPQCGSFDFEDKVVKLYAKDLSESVIQEAFIELSQVDVTFTTKAAVSVSTDNIKYVSAESVVPSTQAVTFSPSFHNQAIMVTKPVQEYKKEYTVQQALFCTSGIVTSIPVPLAGSALLPYHISSTACQAKAHLSSDDSNSNGDSAQVHIATKNREEKAACLRNICLPSEHNPGNQNDFKPTNDDIEMQSSSKLPNDPAIISNFSAAVVHTIVNETLESMTSLEVTKMVDERTDYLTKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSIDKSKSVIPNIDKNAVYKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECKVSMVHGSSLETLPSCPAVTGQKSDLKESAKDQPLKKHNLNSTSLEALSFGQENPFPHSHTFSSTALTCVDGLHVEDKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELAKEFAPATPPSTPHNSSVGSLSENEQNTIEKEEFMLKLMRSLSEEVESSESGELPEVDVKSEHSGKKVQFAEALATHILSLATEMAASHLDNKIIQEPKVKNPCLNVQSQRSVSPTFLNPSDENLKTLCNFAGDLAAEVITEAEKIAKVRNCMLFKQKKNSCYADGDEDYKVEEKLDIEAVVHPREVDPFILSLPPSSCMSGLMYKYPSCESVTDEYAGHLIQILKQEGGNSELIMDQYANRLAYRSVKSGLQEAAKTTKVQCNSRMFPVPSSQVKTNKELLMFSNKEHHQEADKKRQSKRNEGYFCKNQTCERTLDPYRNEVSQLYSFSTSLVHSITKDAKEELTASLVGLPKSLTDSCLFEKSGYEEDNECHVTPELPKSLQPSSQNHRFYHSTGSLNGYGCGDNVVQAVEQYAKKVVDDTLELTLGSTVFRVSETTKSADRVTYAEKLSPLTGQACRYCDLKELHNCTGNSSQHFFRQGSLASSKPASNPKFSSRYQKSRIFHLSVPQIHVNLDKKAVLAEKIVAEAIEKAERELSSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDSDGPDDKDEEHEDEVEGLGQDGKTLLITNIDMEPCTVDPQLRIILQWLIASEAEVAELYFHDSANKEFMLLSKQLQEKGWKVGDLLQAVLQYYEVMEKASSEERCKSLFDWLLENA
What is the function of this protein?
Binds to type II regulatory subunits of protein kinase A and anchors/targets them.
What are the official names of this protein?
A-kinase anchor protein 11, AKAP-11, A-kinase anchor protein 220 kDa, AKAP 220, hAKAP220, Protein kinase A-anchoring protein 11, PRKA11.
What is the protein family that this protein belongs to?
Belongs to the AKAP110 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic in premeiotic pachytene spermatocytes and in the centrosome of developing postmeiotic germ cells, while a midpiece/centrosome localization was found in elongating spermatocytes and mature sperm.
Protein: P37_MYCPN
Sequence: MLKRKKLLQGFLKFLPLIIPATIFVSCARRESNHLIFNISLDHDADASISKFFELYSNNLSKKLDKKVTVSFNIIDDSFTKISNIQTAKADFAFVNSQSIKDNGIEEFNLILQTQTDAFKEDTNLDYYSDGQLKSKAEKMTTLFSKTPYKDWEDTAQQWTGSRYNFLYETNKLINFYRGMILITGSEEEIKKIKEAWDQKKWSDFMNYGIGHGSSGSAGKFQLPDLLLRKHFGSSYPGLQNAINQNPDKFANVRGREIGRDNKIKIVFDDANSFAWTHNDKNATNHFYTPTENNGKGDSEKSNNKNNKVEILTYTDPMLYDIGIVSDTLSDRYQKAIAEVFVELAKTKQDIYGPSYGYNGYNLITDPNKEILDVIHKTYG
What is the function of this protein?
P37 is part of a high-affinity transport system.
What are the official names of this protein?
High affinity transport system protein p37.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYH_ECOSE
Sequence: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGSLEARANYRDALVAFLEQYKDKLDEDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_ACIBC
Sequence: MHLTRLNIERVRNLKTVALHGLQPFNVFYGANGSGKTSILEAIHLLATGRSFRTHIPKNYIQYEADDAIVFAQSATEKIGMQKLASGEQLMKVNGDTVATQGQLAKLLPLQHIDPQSTDIIDHGAKPRRQLLDWLMFHVEPEFYFAWQYYSRALKQRNTLLKTRRNLSLADLEPWNKMLSDYGEILHSQRLSIVEQWNVYFQNDLSQLLPDLEIELEYSPGFHTEQGLMQDLLNQHQKDIERRYTEYGPHRADLRLKTPFGHADDVLSRGQKKLLIIALKLSQIAMLHASNKETVVLLDDLTAELDLTAQQRLIERLSQLGSQVFMTTLDHASVKKHLHDLSISYQLFSVESGQVSLAAP
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_STAAC
Sequence: MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFLALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPIYESTVMEKLHNENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADVNDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRPIGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RUSF1_HUMAN
Sequence: MADDAGLETPLCSEQFGSGEARGCRAAADGSLQWEVGGWRWWGLSRAFTVKPEGRDAGEVGASGAPSPPLSGLQAVFLPQGFPDSVSPDYLPYQLWDSVQAFASSLSGSLATQAVLLGIGVGNAKATVSAATATWLVKDSTGMLGRIVFAWWKGSKLDCNAKQWRLFADILNDVAMFLEIMAPVYPICFTMTVSTSNLAKCIVSVAGGATRAALTVHQARRNNMADVSAKDSSQETLVNLAGLLVSLLMLPLVSGCPGFSLGCFFFLTALHIYANYRAVRALVMETLNEGRLRLVLKHYLQRGEVLDPTAANRMEPLWTGFWPAPSLSLGVPLHRLVSSVFELQQLVEGHQESYLLCWDQSQNQVQVVLNQKAGPKTILRAATHGLMLGALQGDGPLPAELEELRNRVRAGPKKESWVVVKETHEVLDMLFPKFLKGLQDAGWKTEKHQLEVDEWRATWLLSPEKKVL
What are the official names of this protein?
RUS family member 1.
What is the protein family that this protein belongs to?
Belongs to the RUS1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RM33_SCHPO
Sequence: MSFFRVRLERSAIGLSSKVRSVLHSLRLTKRHSVVYCDVNPINAGRIFKVKELVSVSTVKQKLAAGQEKKSLASSSGFTVIHRYNNGLKELNNMFES
What are the official names of this protein?
Probable 54S ribosomal protein L33, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: AMPA2_SHEON
Sequence: MEFSVKSGSPEKQRSACIVVGVYEPRRLSGIAEQLDKISEGYISNLLRRGDLEGKPGQMLLLHHVPNVLSERVLLVGCGKERELDERQYKQIITKTINTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVETTNSSLYCFDALKTRKGETRRPLRKLVFNVPTRRELTLGERAIEHGMAVSSGMHLCRDVANMPPNICNPAYLASQARQLAEIHENLHVSTVGEEQMAKLGMNSYLAVGRASANESIMTVMEYKGAVDSTEKPIVLIGKGLTFDSGGISLKPGEAMDEMKYDMGGAAGVIGTMKAICEMKLPINVVGILAGCENMPSGNAYRPGDILTTLSGQTVEVLNTDAEGRLVLCDVLTYVERFDPELVIDTATLTGACVIALGKHASGLFSSHNPLAHELLNAGEQSGDRAWRMPLWDEYQDMLDSPFADMTNLGGRPAGAITAACFLSRFAKKYNWAHLDVAGTAWNSGANKGSTGRPVPILTQFLINRAGVELGE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Probable cytosol aminopeptidase 2, Leucine aminopeptidase 2, LAP 2, Leucyl aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_BURMA
Sequence: MSKTHFGFETVEENEKAKKVAGVFHSVASNYDLMNDLMSAGLHRAWKAFTIAQANVRPGGKVLDIAAGTGDLTKAFAKAAGPTGEVWHTDINESMLRVGRDRLLDKGVVTPSLLCDAEKLPFPDNYFDVVTVAFGLRNMTHKDSALAEMRRVAKPGGRVMVLEFSKVWEPLKKAYDVYSFKVLPWLGDKFAKDADSYRYLAESIRMHPDQETLKTMMEQAGLDAVKYYNLSGGVVALHVGTKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: Y2802_CLAM3
Sequence: MADSSFDVVSKVDRMEADNAVHQTQKEVEQRYDFKNVGASIEWSGDTILMKASSEERVKAILDVLQTKMIKRGIGLKSLEEGEPFASGKEYRIEVTLKQGIDQANAKKIGKIIRDEGPKGIKSRVEGDELRVSSKSRDDLQQTIALLKGADVDLDLQFVNFR
What are the official names of this protein?
UPF0234 protein CMM_2802.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: NSP1_LOTJA
Sequence: MTMEPNSTTSDHILDWLEGSVSFFPSFLDEPCNNSGYIQEYHLWDQYQTDANTGSSPNATNSTTATIVATSATSTTSLEPCGSNNNQPLSDLPKKRNATDESSLKPPQNKNKRIKTRPMNEPENGDAVRKNKKGGAKANGSNCNSGNSKEGRWAEQLLNPCAAAIAGGNVNRVQHLLYVLHELASPTGDPNHRLAAHGLRALTHHLSSSSSSPTSSGTITFASTEPRFFQKSLLKFYEVSPWFSFPNNIANASILQVLAEEANITSRTLHILDIGVSHGVQWPTLLDALSRRSGGPPSVVRLTVVTAENDQNMETPFSKAPPGYNYYPRLLGYAQSININLQINRIENHSLQTLNAQSISASPDEILIVCAQFRLHHLNHNSPDERSEFLKVLRNMEPRGVILSENNTECCCSGCGNFAAGFTRRVEYLWRFLDSTSSAFKGRESDERRVMEGEAAKALTNQREMNEEKEKWCGRMKEAGFAGEVFGEDAVDGGRALLRKYDSNWEMKVEEKNTSVGLWWKGQPVSFCSLWKLDGNDQGGTS
What is the function of this protein?
Transcriptional regulator essential for Nod-factor-induced gene expression (PubMed:17071642) (Probable).  Acts downstream of calcium spiking and a calcium/calmodulin-dependent protein kinase required for activation of early nodulation gene expression (PubMed:17071642, PubMed:24329948).  Acts as a common symbiosis gene that positively contributes to the early steps of the arbuscular mycorrhizal fungus and rhizobial infection processes in roots (PubMed:23926062).  Transcription factor involved in the positive regulation of the beta-carotene isomerase D27, which participates in a pathway leading to biosynthesis of strigolactones in roots (PubMed:23926062).
What are the official names of this protein?
Protein NODULATION SIGNALING PATHWAY 1, LsNSP1.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPO_SPIOL
Sequence: MATLSSPTIITTTSILLNNPFLPKTPQLSAHHHRGVRSVNGKVSCQTKNNNGNDENNQFQLIQNPNTNTPYLLDRRNILLGLGGMYAALGSEGANYYNTLAAPILPDVEKCTLSDALWDGSVGDHCCPPPFDLNITKDFEFKNYHNHVKKVRRPAHKAYEDQEWLNDYKRAIAIMKSLPMSDPRSHMQQARVHCAYCDGSYPVLGHNDTRLEVHASWLFPSFHRWYLYFYERILGKLINKPDFALPYWNWDHRDGMRIPEIFKEMDSPLFDPNRNTNHLDKMMNLSFVSDEEGSDVNEDDQYEENILLMRKAMVYPSVSDDPNKAELFLGSPYRAGDKMEGDVSGAGILERMPHNSVHVWTRSNTIKGNQDMGAFWSAGRDPLFYCHHSNVDRMWSLWTDVLHGGNFPKTPEYDDYRNAYFYFYDENANPVRVYVRDSFDTERLGYKYEDQELPWMSITQQQQQQQRQQQRQPLLGGRLKTRTFSLVKKVLTELKVMLPLPLKYSVIKTKVDRPKKSRTKEDKLEHEEVLVINFKLGKSKDFIKFDVYINDGTDYKPEDKTKINLEYAGSFTSLTHGGGGGGGDMSHMAEEDMGKNTVLKLALNQLLEDLDATDDDSIQVTIVPKSGTDSIVITGIDIE
What is the function of this protein?
Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.
What are the official names of this protein?
Polyphenol oxidase, chloroplastic, PPO, Catechol oxidase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: PPNP_SHEON
Sequence: MELIEQVAVAKKANIYFEGKVASRSVFFSDGSKQTLGVVLPGEYEFSTSQGEIMHVTSGSFEVLLPNSSTWQAFSEGSQFELAANVSFKIRNNAIAEYCCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: PHNW_BACC0
Sequence: MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPKNGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAQRDELLKCKGQARSLSLDLYDQWETMENQNGKWRFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVNEKYQSPIITSFIYPEGNFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: PAP4_PARMA
Sequence: GFFALIPKIISSPLFKTLLSAVGSALSSSGGQE
What is the function of this protein?
Exhibits unusual shark repellent and surfactant properties.  Forms voltage-dependent, ion-permeable channels in membranes.  At high concentration causes cell membrane lysis.
What are the official names of this protein?
Pardaxin P-4, Pardaxin P1a, Pardaxin Pa4.
What is the protein family that this protein belongs to?
Belongs to the pardaxin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: PAN_METHJ
Sequence: MAEAARHPDDMKTPDELYRYLVDRVAGMESQNQELKEQIRQLESDKRYIETQKIRYEREVRKLKSEIEHLKTPPLIVGTITDIIDSGRVVVRSSAGPRFLVRVSQAVNPTTLKAGVRCTLNQQSLAIVEVLPSTYDSQVYGMELVDAPTETYEDIGGLEKQIMEIREAVELPMTRPDLFEKIGINPPKGVLLYGPPGTGKTLLAKAVAHETHAIFLHTVGSELVQKYIGEGARLVRELFDLAKEKAPSIVFIDEIDAIGASRTEAMTSGDREVQRTLMQLLAAMDGFEPRGDVKIIGATNRIDILDAALLRPGRFDRIIEIPLPDTEGRYSILKVHTRCMNLSEDVDLMEVARLTEGRNGAELNAICMEAGMFAIRKEHPQVDQEDFLTALNKFRCDFERDHRLTTAGVMFA
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPPB_ECO57
Sequence: MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLELGVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIRHKK
What is the function of this protein?
Part of the ABC transporter DppABCDF involved in dipeptide transport.  Responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Dipeptide transport system permease protein DppB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NAGB_CORGL
Sequence: MDIIICKDEQEVGKAAAALIAPFATKGGTLGLATGSSPLSTYQELIRMYEAGEVSFKNCKAFLLDEYVGLTRDDENSYFKTIRKEFTDHIDIVDEEVYSPDGANPDPYEAAAEYEAKIAAESVDVQILGIGGNGHIAFNEPSSSLSGLTKVQALHPKTVEDNARFFNTIEEVPTHALTQGLGTLSRAQNIVLVATGEGKADAIRGTVEGPLTAMCPGSILQMHNNATIIVDEAAASKLENADHYRLMEQLKLR
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ISCR_SHIFL
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: ANGI_HORSE
Sequence: MAMSLCPLLLVFVLGLGLTPPSLAQDDSRYRQFLTKHYDANPRGRNDRYCESMMVRRHLTTPCKDTNTFIHGSKSSIKAICGNKNGNPYGETLRISKTRFQVTTCKHAGGSPRPPCRYRATPGFRSIVIACENGLPVHFDESFFRP
What is the function of this protein?
Ribonuclease that cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs).  Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus.  Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA.  Angiogenin induces vascularization of normal and malignant tissues.  Angiogenic activity is regulated by interaction with RNH1 in vivo.
What are the official names of this protein?
Angiogenin, Ribonuclease 5, RNase 5.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity).
Protein: CEP63_MACFA
Sequence: MEALLERMQNRGHGGGFLTSCEAELQELMKQIDIMVAHKKSEWEGRTHALETCLKIREQELKTLRGQLDVTHKEVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELGILKRSYEKLQKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLANRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELRAALQSQENLIHEGRMQKEKLQEKVKAADTQHAVEAIRLREESLAEKKYTSQGQGDLDSVLSQLNFTHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEAHNNEYRAEIKKLKEQILQGEQSYSSALEGMKMEISHLTQELHQRDISIASTKGSSSDMEKRLKAEMQKAEEKAVEHKEILDQLESLKLENRHLSEMVMKFELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMNTKSQLEISTQMCKKQNDRIFKPTHRRTTEFKNTEFKPTHGQHRHDGIKTEHYKTGLHSPRGQASDSIDPMSRVLSPLSPQISPCSSTRSLTSYSLCKSHSLPSALDTNEANFSDTVSESMNDQEEFMSSCSLPVSPLGSIATRFLEEEELRSHHILERLDAHTEELKRESEKTVRQFTALK
What is the function of this protein?
Required for normal spindle assembly.  Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication.  Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned.  Also recruits CDK1 to centrosomes.  Plays a role in DNA damage response.  Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression.  Promotes stabilization of FXR1 protein by inhibiting FXR1 ubiquitination.
What are the official names of this protein?
Centrosomal protein of 63 kDa, Cep63.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Colocalizes with CDK5RAP2, CEP152 and WDR62 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (By similarity).