PharMolix/UniProtQA huggingface dataset:
Protein: CCA_ACIBS
Sequence: MQVYLVGGAVRDYLLGHSYQEKDYVVVGATPEHMLAQGFQPVGKDFPVFLHPETKEEYALARTERKSGQGYHGFQFFTDTTVSLEDDLIRRDLTINAIAMDQDGKIYDPYGGQNDLENKILRHVSEAFAEDPLRVLRVARFAARYFPYGFQIAPETLQLMQTMADSGELDALTPERVWKETSRALMENHADIYFQTLRDCGALKHLFPEIDALFGVPQRPEYHPEVDCGIHTLMSLQQACKSNYSLDVRFAVLVHDLGKALTPAKELPRHIMHEERGIKPVTQLCERLRVPTQTKQLALSVCKEHLKCHQIMSLKPGTLWRLLQRLDVLRRPERVEAFVQACECDAKGRLGLEDRPYPQAQYMREAMQIVRSIKVQDLPENIKGAEIGEMLIQYRIEALAEFKNQHQSLSHS
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RAB2A_CHICK
Sequence: MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATLAGNQGGQQAGGGCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between active GTP-bound and inactive GDP-bound states.  In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology.
What are the official names of this protein?
Ras-related protein Rab-2A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (By similarity).
Protein: PIGB_DROME
Sequence: MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAGLYKILALLQLDSAHLLVVLPRIVQALLSAYSDYRFFVWTGKRKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFLRNYRLLHRIEHAEVTRLEGSQALVDQWSEALGAQSPNLASLLQNRQSRTGRSILVYQRLKKGEENAFNRGPDSGQHEPDVHDHPPLEDLVLANENENLFN
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 3, GPI mannosyltransferase III, GPI-MT-III, Phosphatidylinositol-glycan biosynthesis class B protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DFX_SYNC1
Sequence: MAEKLEVYKCELCGNIVEVLHGGAGELVCCGKPMNLLNENTVDAAKEKHVPVIEKTNDGIIVKVGSVAHPMEEKHFIQWIELIANGKAYRQHLSPGDKPEACFPLITGPLKVREYCNLHGLWSSEG
What is the function of this protein?
Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center.  Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity (By similarity).
What are the official names of this protein?
Desulfoferrodoxin, Dfx, Superoxide reductase, SOR.
What is the protein family that this protein belongs to?
Belongs to the desulfoferrodoxin family.
Protein: NAMA_LISIN
Sequence: MSKLFSEYKLKDVTLKNRIVMSPMCMYSVENKDGIATDFHFAHYVSRAAGGTGLVILEATAVQEVGRISEFDLGLWNDEQVPALKRLVDGLHYHGAKAGIQLAHAGRKAVLPGEIVAPSAIPFDEKSAKPVELTKEAIKEVVADFKRAAYRAKEAGFDVIEIHAAHGYLIHQFLSPISNRREDNYGGPAGNRYKILSDIIKAVKEVWDGPIIVRVSATDYAHGGLQLEDHIPFAKWMKADGVELIDVSTGGLVNVEPPVFPGYQVPFADEIRRGAGIATGALGLITRGEQAEEILCNERADLIIIGRELLRNPYFAKEAAETLGETIEAPKQYSRAWK
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: PTA_STRAW
Sequence: MTRSVYVTGIDRGDGRQVVELGVMELLTRQVDRVGVFRPLVHDGPDRLFELLRARYRLAQDPATVYGMDYHEASALQAEQGTDELMSTLVDRFHLVARDYDVVLVLGTDFADTQFPDELALNARLANEFGAAVIPVVGGRGQTAESVRAETRNAYRAYEGLGCDVLAMVVNRVAREDREELAARLDSLLAVPCYVLPDEPALSAPTVAQITHALGGKVLLGDDSGLARDALDFVFGGAMLPNFLNALTPGCLVVTPGDRADLVVGALAAHSAGTPPIAGVLLTLDERPSDEVLTLAARLAPGTPVVSVAGTSFPTAAELFSLEGKLNAATPRKAETALGLFERYVDTGDLLKRVSAPSSDRLTPMMFEHKLLEQARSDKRRVVLPEGTETRVLHAAEVLLRRGVCDLTLLGPVDQIRKKAADLGIDLGGSQLIDPVTSQLRDSFAEKYAQLRAHKGVSVELAYDVVADVNYFGTLMVQEGLADGMVSGSVHSTAATIRPAFEIIKTKPDTKIVSSVFFMCLADKVLVYGDCAVNPDPNAEQLCDIAVQSAATARQFGVEPRIAMLSYSTGTSGSGADVDKVREATELVRLRRDDLKIEGPIQYDAAVEPSVAATKLPGSDVAGQASVLIFPDLNTGNNTYKAVQRSAGAIAVGPVMQGLRKPVNDLSRGALVQDIVNTVAITAIQAQSPHEKATAQ
What is the function of this protein?
Involved in acetate metabolism.
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIS_CERVI
Sequence: CTTGPCCRQCKLKPAGTTCWRTSVSSHYCTGRSCECPSYPGNG
What is the function of this protein?
Specifically interacts with the alpha-1/beta-1 integrin (ITGA1/ITGB1).  Exhibits highly inhibitory effects on cell adhesion and cell migration to collagens I and IV.  Also shows in vivo anti-angiogenic activity (By similarity).
What are the official names of this protein?
Disintegrin CV, Disintegrin CV-short.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Short disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACEK_SALG2
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWEPLLMRILSDLPLRLPWQNKSRDIRYIIAHLTETLGEDALPRCHVQVANELFYRNKAAWLVGKLTTPDGTLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLLAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRGMVMLVFTLPGFDRVFKIIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIDPALMALLRQEVPEKITDLGEHIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPARYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQTRIKEGHVEDVYAYRRRQRFSVRYGAISSTANSS
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_PHYS2
Sequence: METKNAKAIARKVSIAPRKARLVVDLIRGKNIAQAQAILTFTPKVAAPVILKLLNSAISNAVNNLKLNREQLYVKEVFVNEGLRLKRMFPRAKGSGDMIKKRTSHITLVITSSTNLQTSKEEEQSGSKN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: BPT_RALPJ
Sequence: MSKLKELPLSALQFYATAPYACSYLDGRLARSQVATPAHLINADVYSKLVRAGFRRSGIFTYRPHCDDCHACTPCRVVVDQYSPSRAQRRAAERHQGLEALVAPLTYVEEHYQLYLLYQSVRHAGGGMDHDSRDQYEQFLLQSRVNSRLVEFREPPESPSAGKLRMVSMIDVLEDGLSSVYTFYDPIEQKASYGTYNVLWQIAQAQALDLPYVYLGYWIEQSRKMAYKALFQPLELLVNGEWRRFEDVVPRTTEE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_GEOSL
Sequence: MFKEFKEFAMKGNVVDLAIGVIIGGAFGKIVTSVVNDIVMPPIGLLMGKMDFSNLFIDLSGKGYESLKAAKDAGAPVISYGAFINTVLDFVIVAFVIFLVIKQINRLKKEPVPAPPDTKECAFCCSAIPIKATRCPHCTSEQK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GOLI4_RAT
Sequence: MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYLELQTQLRKAEAVALKYQQHQDSLSAQLQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELRKQHSDLEEEHRKQGEDFSRAFNDHKQRYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVKTQVAEYKQLKDTLNRIPSFRNPDPAEQQNVTFTHGTHPPQGYNVREKLTGELQEGQQNHDAMPRRMEEKPLSSMQKEAGFQALEEQNQVEPREPEGRQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWRDQRRQNAAHLLDGRPQAEIEHSTKAATNFRSPYEEQLEQQRLAARRDEEAQRLREHQEALHQQRLHGQLLRQQQQQQYLAREMAQQKQADHEEGQQQYQLRQQAHSDAVENDVAQGAEDQGIPEEEGGAYDRDNQRQDEAEGDPGNRQEFHEPGHQEGDPEAEADRAAAQDINPADDPNNQGEDEFEEAEQVREENLPEESEERKQSEAKQGNVEMDEHLVMAGNPDQQEDNVDEQYQEEGEEEVQEDLTEEKKRELEHNAEETYGENPDDKNNDVEEQGVPNRAHPKGRQEHYEEEEDEEDGAAVAEKSHRRAEM
What is the function of this protein?
Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi.
What are the official names of this protein?
Golgi integral membrane protein 4, Golgi integral membrane protein, cis, GIMPc, Golgi phosphoprotein 4.
What is the protein family that this protein belongs to?
Belongs to the GOLIM4 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Membrane; Lipid-anchor. Note=Localizes to cis and medial Golgi cisternae. Probably cycles between early Golgi and distal compartments like endosome.
Protein: Y902_PSYIN
Sequence: MLDIKLLDIIACPLCKGKLSYKKNSNELICKFDHLAYPVIDGIPALLKVKARTISSDEE
What are the official names of this protein?
UPF0434 protein Ping_0902.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: BIOD_BUCBP
Sequence: MKNCWFITGTDTNIGKTVSSIILLELARRYGYNTSGYKPIAAGCRTNDFKQYNSDAVLLRKFSTVKLSYQEVNPYLFIDPVCPFFTNEKNHMNVCMNKLSSGLQRLKKKSNWILIEGIGGLHTPFSNEFVMSDWIKKENLKTILVIGIKLGCINHAILTQKAILSSGLEFFGWIANYLLPTDTYNLTHIDILKKNMKSPYLGCIAYTPNIYNQIHHIPITIKLPLQN
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_PARXL
Sequence: MHEKSLTELRAALTARECSAVELAQLYLKRIEAANSLNAFIQVDPDLTLAQAKAADALLHTGHAGPLVGLPIAHKDVFVTKGWRSTAGSKMLSNYESPFDATVVARLQNAGMVCVGKTNMDEFAMGSSNENSYFGPVQNPWDVKAVPGGSSGGSAAAVAARLAPAATGTDTGGSIRQPASFSGITGIKPTYGRVSRYGMIAFASSLDQGGPMARSAADCATLLNAMAGFDGRDSTSLVRDDEDYTRYLGQPWKEDGAGKPLAGLRIGLPKEYFGAGLADDVRASIDAALKQYEALGATLVEVSLPKTELSIPVYYVIAPAEASSNLSRFDGVRFGHRAAEYRDLLDMYKKSRAEGFGPEVKRRILVGAYVLSHGYYDAYYLQAQKIRRIIAQDFQEAFRQCDVIMGPVAPTVAWDLGAKGDDPVQMYLADIYTLSVSLAGLPGMSVPCGFGAGANAQRPVGLQIIGNYFNEARMLQVADAFQRATDWHRKAPAGV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RECX_STAAW
Sequence: MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEIFTELYREQQELDDIIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_BURP6
Sequence: MQIGQRLGTPLSPSATRVMLLGAGELGKEVIIALQRLGVEVIAVDRYPNAPGHQVAHRAHVIDMTDPDALRALVDAERPHLVVPEIEAIATDALAAIEAAGVCEVIPTARATQLTMNREGIRRLAAEELGLPTSPYAFAQSFDEFAAAVARIGFPCVVKPVMSSSGKGQSVVRSEADIEPAWRYAMAGGRVNHGRVIVEGFIRFDYEITQLTVRAIDPASGQTRTSFCAPIGHLQVAGDYVESWQPQPMSAKALERARDIAHRVTSALGGRGIFGVELFVRGDDVWFSEVSPRPHDTGLVTLASQRQSEFELHARAILGLPVEPALATPAASAVIYGGLDEAGIAFEGVRDALAVPGADLRLFGKPESFAKRRMGVALATGANVDEARERAKRAAAAVRPVSAR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: OFOA1_SULTO
Sequence: MRLSWVIGGAQGTGIDTAANIFGNAVASAGYYIYGNREYYSNIKGRHSYFSLTISDKRVRSNTQKIDILVSFDAETVFQHFYDVKDILIYNKAVETTKIDAVQSMEPELAERIKDFLTKQGYETTVKGALEYASKNNVTLIPVNYDEIAKKVADEMKVPLSVTERVKNIVGITISYKLLGLDVNYLIEAINSTFKQDLYRKMNELAVKDSYDIVESRYNLKPSSKERRRFWLDGNTAVAIGKIYGGVRFQSYYPITPASDESVYIEAHQDVLMEDPITGDKKKGTIVVVQAEDELAAINMAIGAALTGVRAATATSGPGFSLMVEGLGWAGMNEVPVVITYYIRGGPSTGLPTRTAQSDLIFPIFAGHGEFPKIVLASGDHAEAFKDAIWALNLAEKYQTPVIHLVEKTLANSYSTIPYEELELDKLKAERGKIVESGDISYKRFKFTEDGISPRAFLGKATMYYTGDEHNEEGHISEDVVNRTMMYEKRMKKLEVADKEIPEESRVKIYGDLNSRNLIITWGSPTGVLRDILEESNFDFTLLQIRMFSPFPKNLVSKLMEGRDKIITVEGNYLAQTSLLVKMYTGKDVTNSILKWNGRPFLRDELEEALIKVIKDGEKRVVLNGGI
What is the function of this protein?
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
What are the official names of this protein?
2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha, OFOR1.
Protein: MURG_TREPS
Sequence: MRFRARVSQSTAKCVVFTGGGTGGHIFPGIAVFQALAQQAAVRVVWIGAARGADRSIVESAGLEFCGITAGKWRRYASVRNFFDVFRVLVGTVQSYCILRALRPQALFSKGGFVSVPPCIAAWLLRIPVVTHESDISPGLATRINARFADRILVSYPHTSCYFPRARRAAVHCTGNPVRQDFFSAQAERAYQFLRIDQKKPLLTVLGGSSGARDLNARVLSCSTFLTERFYLVHQFGAGNEDQMHTITNSLSVNARHAYMSFPFIQAHLPDILAASALVLSRAGANAVWECAVLGKPMILFPLERGSSRGDQIENAEYFSAHGAACILRAQDEKGHQLVSLLTELFHPSCARIEEMARASYTLGIGNAAYDIAQQLQTFIKEGM
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UNG_CHLAB
Sequence: MQNAFTIDQLPLSWQEQLENEWSQPYMYKLREFLQSEYSQKTIYPAKDNIFTALKSTPFDSVRVVILGQDPYPGEGQAHGLSFSVPQGVRLPPSLVNIFSELHADVGVKNTTGCLQSWADQGILLLNTVLTVRAGSPFSHAGQGWEQFTDAIITKLIENRSHVIFVLWGNAARKTCDLLFRSTHKHAILAAAHPSPLAAHRGFFGCSHFSKINYLLKKLNKPMINWKLP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INT10_DROME
Sequence: MPSQEENELYMVKEAQRLRKSDPCAAMAWIITAKTLYPNAFNLQYEAYLLERDAQNYEEAAKCFSAIATNFQNQHTELWQEINSLTNALRNENETTPEHEFYVKMYKHLTPEVQHNIFMHTINHSADNLERIYIYILMFNKFPKSAITQAPRLLEMLAEGMKTEPDLYQRILVEEVLPMIQNKPPELSPNLACRLYTSSLEFYLRQIMDESDTADAWKNIFKVLMICGQMMGWEPFLPFSKHVNQNVYWEKLVDILSGSPAGSSQVLFYATTLFIYSLHGYIRNCKLRIEDADVTHVLVEGFMEWSPEGDGSEVPSMEPPKFSLTTAISPELSKAFLHAAQCWQLLNTDQFQRDFSQLMLALPLAPWISRFLFDLAIYFGHRDEANKLMADMTTQSSLVQSLQILSLNLMQGSMTLQGFQCILKILSELPTTQGQLLENMSLKGHRHMVFLPLTRSALVQYCVGAIISRLSRKVFEPNVPDRLLGDILVLQQLNLLNDVLLTQQIFNLIKQRKSFNLRTLSTYIINIDLLEELSHIWNSQQEDNFELTSSPNSSGTPTATTVAGGSQSRRIGTRGADKGARDEFRAITRQQIARCNENVITLLANFINQEHLMLAQHIFGISQPVETIVIK
What is the function of this protein?
Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing (PubMed:21078872, PubMed:23097424).  May be involved in the 3'-end processing of the spliceosomal snRNAs U1, U2, U4 and U5 but is probably not essential for 3'-end processing of the snRNA U7 (PubMed:21078872, PubMed:23097424).
What are the official names of this protein?
Integrator complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y5617_BRASO
Sequence: MLGWVVTFLVIALIAGILGFGGVAGASIEIAKIIFFIAIVLFLVSAVVGLARGRTRV
What are the official names of this protein?
UPF0391 membrane protein BRADO5617.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FPG_XANP2
Sequence: MPELPEVETVRRGLIPVLQGAVIESAEARRPDLRWPLPDNFAERLAGRRVEAIGRRAKYLLADLDGGEVMILHLGMSGSIRIEGGAVKGRPGRFHHPRGAGGPHDHVVLHLAGGATVTFNDPRRFGAILIVPYDQIMSHPLLAGLGPEPLGNGFNAEYLARACARRHTSLKAALLDQKLVAGLGNIYVCEALFRAGLSPRRLAHTIATAEGAPTRRAERLVIAIRDVLREAIHAGGSSLRDHRQVNGELGYFQHTFKVYDREGQPCQTLHCKDTIRRIVQNGRSTFYCPTCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RTC5_COLGM
Sequence: MGQVLSDESSRHLSHEELTHELASRFADKCFTSLEIYSFKDVFKSLADNQGGIRYLKEDTLARFLEIPDILHVSPVVFQMVSYIGAFPFLQNAPAVLGLDQMVMVVVIMTQRHKRVLAKGATDRAKLLFKSLAVHDRTASEAAVAAEKSSKEEQATQSQPRSHVAGFAVDEPVEEPEDDDDDLEIAAFELLDINDAVWQGDAPKVQGAMIPADNFRKLLMLLILIAPLNAQERLSMYSTRVTGDELDSLRATAEHILAAFLNVEKAPGIKFSQYNRVLPVCFPNLFSGFSPLFEHFLFSKNLDFTKHKGEEPVAEKQPEEIVQPLLPEPGEILNLNVLSQLSFFLPGSDLFRRLRPLYSGNKDGFSTGSFEGKVFNWRAPTILLVRGTRIDDDPRGSQQSTFAASIPPRRFPSGSKGERLTFGVYVSTPWKHTAKETFGEGDTVLFQLEPVHDVFPASRYNSEFISFTKAPTNRPMLGVGCPHPRPSQAHRRNEMLSLGSVSLLLDDSFEYGVFNHDWTAGGGAFATSVSRKFDFQDRFEIESLEVWGCGGDEEAKSQADRWAWEHREAEARRKVNLGTGDNDADRALLEMAGLVGSGRSGGSMA
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3B_LACLM
Sequence: MIKFSINKTAFQNALKITKQAIGSKVTIPALTKLKIEVEEKGITLIGSNGQISIKNFLPADNKDASMLISGTGSVLLEAAFFENVVSQLPEVTLEFIEKEQKQVLLTSGKSEITLKGLDSEIYPHLQEISEGSSLKMKVKVLKEIFTETVFAVSTQENRPIFTGVHLETLSTGELKAVATDSHRMSQRLLPLEDTDLKFDVILPSKSINSFKNVFTNDEEEIEIFISGSQMLFQNETISYYSRLIEGSYPDTNRLIPNEADYTLDLVFDAAQLRHTMDRARLLTVMTTNGTVKLTVSGDSVVTTANSPEVGSVHEELTALSKEGNDLSISFNPEYLIDALKVIKAPEVRIRFISNVRPFTLQPRNEESGFVQLITPVRTN
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_RICBR
Sequence: MNNIFKGLITAIITPFRDNKLDLNALEKILEYQINAEVNAVVIAGSTGEGSSLSFEEYKLLLQTAKDIVNKRIPVISGCSSNNTACAIELAAESTKIGVDGFMISPPSYLKPTQGGIYKHFEAIHEASNLPIMLYSVPSRTGVDFTDETILKLSKLSRILALKDAGIDLERPLRIKSVINKEFNLLCGNDDLSLAFNAQGGVGCVSVASNITPKLCKELQEKWHNNDVKGALGIHQRLLPLYKALFVESNPIPVKYAMYYLGFCTNEIRLPLTEATDTTKKQIEEIITSLSIKV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.