PharMolix/UniProtQA huggingface dataset:
Protein: FBH1_CHICK
Sequence: MHLTADDCEALSRSTEGLSSLTQPLNQRRSRGDVNRGLQPTHRTRTQPGAQGRQKNIMDYFKVSQRQQAVAGRTKDISIKEEVLDPFFAEDDESSISSVMETSGDSSSFLENEYMGNSRKRPLSSTAPGRLQIENDLWGEPEKKAVVVHPEHSQIKQELDDEIEIEPVPDSHYGLLGTRNWEVPQGSIEDLPDEVLRSIFAFLPVTDLYQSLSLVCRRWRIIVGDPWFIPWKKLYHQYLVKEDMALRRVEQVLQDFAITGQHKECILGLIRCVSTIPTSRNVDPSAVLQCLKGHHLFSRAEVCITNKLPHLQSKTGPEYMWAIITAMVLFSDGVRDIQRLMACLQRPCSSLSIVDVTETLYCIATLLYAMREKNINITNRIHYNIFYCLYLMENASVTAPQVVEEETPSSRCRQDFWSSSLSEVKLTHEQQRILNHKIERGQIVKIMAFAGTGKTSTLVKYAEKFADLSFLYVTFNKAVAERGRLVFPRNVTCKTFHSLAFGSVGKLYKEKGKLNFSKLSAYSVSFLIQNREGQSIFIRGKTVSQTLENFFASSDEEICEEHTPVWFKNTHGERKLVTPEEKRINVEEAKEIWRNMKKLDGDVERKYKITCDGYLKLWQLSKPQLSGYDAIFVDEAQDCTPAIVDIVLSQTCGVILVGDPHQQIYSFRGAVNTLYTVPHTHIYYLTQSFRFGPEIAYVGATILDVCKGIRNKTLVGGNQEGDVRGSMEGKITMLSRSNFTVFEDAAKLAGRERQIKIHIIGGLVRFGLSKIYDIWKLSQPADEREKANLVINDSFIKRWEENEGFIGLKDYATRVDDKELEMKIRIVEKFKERIPELVQKIESSHVLQEAMADYLIGTVHQAKGLEFDTVLIADDFVDVPCARDNNQRRPQFIIGMCPEDEWNLLYVAVTRAKKCLLMSQSLEHLLALAGEHFLRVELMGEAVKTGVACSTQQCTQTLQSGIRLVVKKLPLIHSNGSRDMGGYLCYSCVQKRFGSMTPLAFLPALQEEPIVL
What is the function of this protein?
3'-5' DNA helicase and substrate-recognition component of the SCF(FBH1) E3 ubiquitin ligase complex that plays a key role in response to stalled/damaged replication forks (By similarity).  Involved in genome maintenance by acting as an anti-recombinogenic helicase and preventing extensive strand exchange during homologous recombination: promotes RAD51 filament dissolution from stalled forks, thereby inhibiting homologous recombination and preventing excessive recombination (PubMed:17283053).  Also promotes cell death and DNA double-strand breakage in response to replication stress: promotes the endonucleolytic DNA cleavage following prolonged replication stress via its helicase activity, possibly to eliminate cells with excessive replication stress.
What are the official names of this protein?
F-box DNA helicase 1, DNA 3'-5' helicase 1, F-box only protein 18.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Accumulates at sites of DNA damage or replication stress. Localizes to the nucleoplasm in absence of DNA damage.
Protein: RL24_CLOAB
Sequence: MANKIHVRKQDSVVVISGKDRGKIGEVLAVNPKKGTVLIKDVNVVVKHQKANKENMQGGLIKKEAPINSAKVMLYCTKCKTATRISKKVLDDGTKVRVCKKCGETF
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: AGL9_SINAL
Sequence: MGRGRVELKRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEVALIIFSNRGKLYEFCSSSSMIRTLERYQKCNYGPPEPNVPSREALAVELSSQQEYLKLKERYDALQRTQRNLLGEDLGPLSTKELELLERQLDSSLKQIRALRTQFMLDQLNDLQSKERMLNETNKTLRLRLADGYQMPLQLNPNQEDHHVDYGRHDQQQQQNSHHAFFQPLECEPILQMGYQGQQDHGMEAGPSENNYMLGWLPYDTNSI
What is the function of this protein?
Probable transcription factor active in inflorescence development and floral organogenesis.
What are the official names of this protein?
Agamous-like MADS-box protein AGL9 homolog, MADS D.
What are the subcellular locations of this protein?
Nucleus.
Protein: HOA_ECO57
Sequence: MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSIEVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQAGARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGATCIYVVDSGGAMNMSDIRDRFRALKAVLKPETQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAVDKLGWQHGADLYALMDAADDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLRNNK
What is the function of this protein?
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde.  Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: RL20_UREU1
Sequence: MRVKGGSVTRQRRKRWLEKAEGSWGTRNTSYRIARQTVIRAAEYAYRDRRNKKRDFRKLWISRINAAVRELGYTYSQFMNALVKANVVTKDGQGLNRKMLSELAINNPEAFNQLVNKVMK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RECO_ALBFT
Sequence: MATQRISDEPAYVLHRHDWSESSLILEVFTRHHGRIALVAKGVKRPSSSFRPILLPLQLLHVAFGGDAEIRILKAAEWQGGHVMPTGDALMSGLYLNELLLTLLARDDPHTRLFDVYTQVVQVIASGHGEVLQSALRAFELLLLREIGLLPLLDAQTMTLLALDPESRYSLVPEGGLRQTNDADRASLSGAQWVALQQSLVDSAPFTATLRACSEVMTQLKPQLRALLNYHCGVQTLRTRQMMIDLQSLSL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: NCA1_ARATH
Sequence: MTTTSVCPFSKAARPDDGSTRKQGEITASGCPFSKAARPDDASARKQGETTASGCPFSKSARPDENGSKGCPEQEGNLNKDSTDSATVPAKCPFGYDSQTFKLGPFSCMLCQALLYESSRCVPCTHVFCKVCLTRFKDCPLCGADIESIEVDENLQKMVDQFIEGHARIKRSVVNGTEKEEVENDNKKVIYADVSMERGSFLVQQAMRAFSAQNYESAKSRLAMCTEDIRDQLGREGNTPELCSQLGAVLGMLGDCSRAMGDSSSAVKHFEESVEFLMKLPLNDLEITHTLSVSLNKIGDLKYYDEDLQAARSYYDRALNVRRDAMKHHPNAPSQILDVAVSLAKVADIDRTLQNEVAATDGFKEGMRLLESLKLDSEDSALEQRRLSVLEFLKKQVETDAETAL
What is the function of this protein?
Has holdase chaperone activity that may fold catalase to a functional structure (PubMed:25700484).  Not required for the peroxisome import of catalases (PubMed:25700484).  Required for the activity of catalases and acts mainly at the post-transcriptional level (PubMed:24285797).
What are the official names of this protein?
Protein NCA1, NO CATALASE ACTIVITY 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AC152_NPVAC
Sequence: MNFFAMQKSSLLPDTPYTVQSLQIVDYFIRIVYTVRYAPNILLHYQLFCITKKFIFAWQVPPPLLSYQSCSTDKQYKYSCRSTRKHSSSLTA
What is the function of this protein?
Acts as a transactivator of AC102 and HE65 genes.  Therefore, participates in the global recruitment of G-actin to the host nucleus.
What are the official names of this protein?
Protein AC152.
Protein: FENR_RICFE
Sequence: MTHTTDVVIIGTGPVGLFAVFQAGMLGMKCHIIDAQEIIGGQCITLYPEKPIYDIPAYPKIAAEELIKQLELQAAPFKPVYHLNQQAIELNKQDDFFEIKTSKNTLIKSKVIIIAAGAGSFGPNKPPLANIEDFEGKSVFYFINDKSKFAGKNIVIAGGGDSAVDWAISLSEIANKIYLVHRRDKFTAAPESVRQLRHIAETGKIELVTGYQLNALDGNNSELQSVIVKDLQNNTRKLDANILLPFFGLKQDLGSLANWGLNVKLHHIEVDNSYYQTNIEGIYAIGDIAHYAGKLKLILTGFAEAASSLHHAYSRVFDGKALHFEYSTTKYGERK
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: ARGC_CAMJR
Sequence: MKIKVGILGASGYAGNELVRILLNHPKVEISYLGSSSSVGQNYQDLYPNTPLNLCFENKNLDELELDLLFLATPHEFSAKLLNENLLKKMKIIDLSADFRLKNPKDYELWYKFTHPNQELLQNAVYGLCELYKEEIKKASLVANPGCYTTCSILSLYPLFKEKIIDFSSVIIDAKSGVSGAGRSAKVENLFCEVNENIKAYNLALHRHTPEIEEHLSYAAKKKITLQFTPHLVSMQRGILISAYANLKEDLQEQDIRDIYTKYYQNNKFIRLLPPQSLPQTRWVKSSNFADINFSVDQRTKRVIVLGAIDNLIKGAAGQAVQNMNLMFDFDEDEGLKFFANL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_SACEN
Sequence: MAKKALINKAAAKPKFKVRGYTRCQRCGRPRSVFRKFGLCRVCFREMAHAGELPGVSKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: PIMT2_ANADF
Sequence: MLARSLLPALALLLAATAGGDACADRGHPSAERSTPETERRRMVEEQLAARGIRDRRVLEAMGKVPRERFVPEQWRSLAYLDEPLPIGRGQTISQPYVVAFMAQALALRGGERVLEVGSGSGYAAAVLAHLAGAVYGIELEPELHARSVETLAELGYGNVHLRRGDGFLGWPERAPFRAIVVSCAMEEIPAPLWEQLVQGGRIVYPKGPEGEVQLLVVVTKTARGPREEHLAPVRFVPMRRGG
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase 2, L-isoaspartyl protein carboxyl methyltransferase 2, Protein L-isoaspartyl methyltransferase 2, Protein-beta-aspartate methyltransferase 2, PIMT 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOX28_ORYSI
Sequence: MERQGLDLGLSLGLGLTTAATWPAAGFCLNSGMAEQEVIRRDDVVAATAAEDERFACSPGSPVSSGSGKRGSGSGSGDEVDDAGCDVGGGGARKKLRLSKDQAAVLEECFKTHHTLTPKQKVALAKSLNLRPRQVEVWFQNRRARTKLKQTEVDCEHLKRWCDQLADDNRRLHKELAELRALKATPTPPAAAPPLTTLTMCLSCKRVANAGVPSPAAAIFPGHPQFLCGFRDHAGAASSSYGGASSGLAKAVRAAR
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX28, HD-ZIP protein HOX28, Homeodomain transcription factor HOX28, OsHox28.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUG1_LIMKU
Sequence: MFTMKKSLLFLFFLGTISLSFCEEERSADEDDEGEMTEEEKRSIRDKIKTMAIDLAKSAGTGVLKTLICKLDKSC
What is the function of this protein?
Has antimicrobial activity against Gram-positive bacteria S. aureus ATCC 2592 (MIC=10. 0 uM), S. aureus ATCC 43300 (MIC=15. 0 uM) and B. subtilis (MIC=40. 0 uM), against Gram-negative bacteria E. coli ML-35P (MIC=10. 0 uM), P. aeruginosa PA01 (MIC=5. 0 uM) and P. aeruginosa ATCC 27853 (MIC=5. 0 uM) and against fungus C. albicans ATCC 2002 (MIC=10. 0 uM).
What are the official names of this protein?
Rugosin-LK1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PRIS_METST
Sequence: MSVELKPASKYERKIFYKEEWNVKDVPDFIRNSLTSREFGFDHYGNGPNDRYKVFVDDLRLKRFIKVKQPFAAYCSVAFYDKPNQRKGWQKSELVFDVDAKDIPIRTCDCAEGEVCEKCLNQAKEIVLMIRDVLSGDFGLTNINLIYSGRGYHVRVLDEDVMDASSELRGDIIQYVTGSKLPDLSNEYGFNDLQPFIIPFGYPKNFTRWSKYTILHLRRSSKLDDVNNQLLRDVLKHRNLLQEDLWGMFRSNIGPIRYKKVMNAISRINMQITDTKVSIDLKRILRLPSTLHSKVSMKSTLIKNIETFDPFDDAVPKFVYERND
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: HSP1_SAGIM
Sequence: MARYRCCRSQSRSRCYRQRRRGRRRRRRTCRRRRASRCCRRRYKLTCRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1, Cysteine-rich protamine.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MURC_RUEPO
Sequence: MTPATKLPQDVGPIHFVGIGGIGMSGIAEVLLNLGYRVQGSDLKGSKITERLAGLGAEIFEGQRAENLDGAAVVVISSAIKPGNPELDGARAQGLPVVRRADMLAELMRLKSNIAIAGTHGKTTTTTMMAELMVAGGFDPTVINGGIIHAYSSNARMGQGEWMVVEADESDGSFNRLPATVAIVTNIDPEHMEHWGSIEALRQGFYDFVSNIPFYGIAVCCTDHAEVQALVGRITDRRVRTYGFNAQADVRATNLTYKGGVAHFDILLQHEDMVIEGCTLPMPGDHNVSNALSAVAVARHLGMKADEIRAALAAFGGVNRRFTKVGEVNGVTIIDDYGHHPVEIAAVLKAARQASEGRVIAVHQPHRYSRLSNLFDDFCACFNEADVVAIAEVYAAGEAPIPGADRDALVAGLIRHGHRHARAILSEEDLERLVREQTRPGDMVVCLGAGTISAWANGLPDRLKG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_BURM9
Sequence: MLTLAHYLVLGAILFAIAIVGIFLNRRNIIIILMAIELMLLAVNTNFVAFSHYLGDVHGQIFVFFVLTVAAAEAAIGLAILVTLFRKLDTINVEDLDQLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SMCO1_MOUSE
Sequence: MTHETTTLISLKEAMKRVDNKLRALDTQFKELDVTKDNLTLRFEHHSKTLASQAAQDEIWTAALALGFTSMELNIVYSYVIEVLICLHTRMLQKLPDLVRSLPTLASVLRRKAKNKHVRLVWESVLQEYGLQERDVSALCTFFIVHGNKGEHYAANVRRMYIKDVSFMITNMVKNQALQDGLLRAVQIIEKGKQAQDPENSRAPLKELMPPVKD
What are the official names of this protein?
Single-pass membrane and coiled-coil domain-containing protein 1, Single-pass membrane protein with coiled-coil domains 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: UGPC_BORA1
Sequence: MATLSFRNLKKTYAGNVPVIHGIDMEIKDGEFIVIVGPSGCGKSTLMRMVAGLETVTSGEILIDDKPVNDLEPAERDIAMVFQNYALYPHMSVFENMAYGLKIRKVPKAEIQKRVEEAAQILELGKLLDRRPRQLSGGQRQRVAMGRAIVREPKVFLFDEPLSNLDAKLRVAMRLEILKLHRRLHTTSLYVTHDQVEAMTLAHRMVVMYQGVPEQIGTPMEVFEKPASTFVAGFIGSPPMNLIEVDVAGDGTMTAEGMPLQISPLQVPSAVRGRKIIMGLRPEHMLLNAEGIPVEIEMIETLGSEQLVHGRRGKHMLVVRCTTRQLSESTVKVGDTMNIGPDGRHDLHWFEPDTGRRVQGL
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CPOB_PSEPU
Sequence: MRMCRRVVTVLALSLPLAAWAEVPVVDDNAGSYPPAGYGTSGAYAGSGASAPASAQGQLFMQLQQMQDQLSRQQGIIEELQNDVSRMKQENLERYQDLDRRINSGAAPAATPDNSSGGGASNAAPDAAAGAAAQQPAGSSQPGDPAKEKLYYDAAFDLIKQKDFDKASQAFNAFLRKYPNSQYAGNAQYWLGEVNLAKGDLQGASQAFAQVSQKYPKHSKVPDSLYKLADVERRMGHTDKVKGILQQVVTQYPGTSAAQLAQRDLQKL
What is the function of this protein?
Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
What are the official names of this protein?
Cell division coordinator CpoB, ORF2.
What is the protein family that this protein belongs to?
Belongs to the CpoB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NMT_ASHGO
Sequence: MGDSGDAQKMQRLLEMLALNSGDMSKLTQQQRKAFEEYKFWKTQPVARFDEKVEEEGPINPPRRVEDVRDEPYPLLEEFEWRTMDITTGQDLEDVFVLLNENYIEDKDSTFRFNYTREFFNWALKPPGWRKEWHVGVRVRQSGRLVAFISAVPTTLEVRGREMKSVEINFLCIHKKLRSKRLAPILIKEITRRVNKCDIWHALYSAGIVLPSPISTCRYTHRPLNWSKLFDVGFTALPANATKTQMLAKYTLPKKPLVEGLRPMTDADVDGAFDLFNRYQKRFELIQTFDKSEFRHWFLGNEETPSVIYSYVVQNSEGKITDFVSFYSLPFTILKNPLHKELGIGYLFYYASDADFDYEDRYDPTATELLRKRLTQLINDVCILARDLKMDVFNALTSQDNALFLEDLKFGPGDGFLNFYLFNYRANPIRGGLTEDKKFDAKNRSNQGVVML
What is the function of this protein?
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
What are the official names of this protein?
Glycylpeptide N-tetradecanoyltransferase, Myristoyl-CoA:protein N-myristoyltransferase, NMT, Peptide N-myristoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_XYLFT
Sequence: MNIPTKFTTSKIRSDFLEFFKNKGHKIVPSAPLVPSNDPTLLFTNSGMVQFKDVFLGAEKRSEVRVADVQCCLRAGGKHNDLDSVGYTARHHTFFEMLGNWSFGDYFKKEAIMWAWELLTQVWELPPERLLVTVYHTDDESYALWRDMVGVPEDRIVRIGDNKGAPFASDNFWQMADTGPCGPCTEIFYDHGEHIPGGPPGSPGEDGDRFIEIWNLVFMQFDRQSDGTLVPLPTPCVDTGMGLERLAAILQHVHTNYEIDLFQTLILKAAELTAVADVQNKSLCVIADHSRACAFLIVDGVLPSNEGRGYVLRRIIRRALRHGWMLGVRQPFFNNMVPTLIAVMGDAYPKLQAAAESVMRTLLAEEERFAETLDVGMKIFNEVAAKVANGVIPGSDAFRLYDTYGFPVDLTADIARERGMRVDMAGFEAAMTQQRKTARAAGKFGRGVQLSAERAATLSPTVFLGYEQLQADDLRVVALLSDGGLTDSASVGDEVIVLTDRTPFYAESGGQVGDIGTLMASDGVRLEVTDTQKLMGQFHGHVARIVQGGVKVGDVLSGSVAVARRKMVALNHSATHLLHCALRSVFGTHVVQKGSLVAPDRLRFDFSHFEPISAAQMTLIERMVNDEVRANHLVMIEQMGMQAALDAGAMALFGEKYGEHVRVVTMGTSVELCGGTHITRTGDIGLFKIISECGVSSGVRRIEAVTGESALNHVLAEEHRLYEVAGLIGSNANNVVNHIRQLTDRQKTLERELEKLKGKLISGTITDLLSMAVNVADVKVVAARLDGLDGKALREALDRLKLQLSDAVIVLAGVTGGKVALVTAVNGPRAMGKVKADTLLSHVATQINGRGGGRVDFAQGGGEDGPSLRSALDGVATWVKQHLN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR12_KARBO
Sequence: SPALDDERNDNFIRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-12, FMRFa-12.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERH2_CAEEL
Sequence: MSTSSHTVLLIQTSPRLDSRTWGDYESVTDALDALCKMFEDFLSKKSAAPVTYDVSQVYEFLDKLSDVSMMIFNRETGQYIGRTRAWIKQQVYEMMRGRCQHPEGGEKVIVGY
What is the function of this protein?
Required for chromosome segregation and cell division in early embryos (PubMed:31216475).  Component of the pid-1 and tost-1 variants of the PETISCO complexes, which have roles in the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs) and embryogenesis, respectively (PubMed:31147388, PubMed:31216475).  Within the tost-1 variant of the PETISCO complex binds to splice leader SL1 RNA fragments to possibly play a role in their processing (PubMed:31147388).  Promotes the biogenesis of 21U-RNAs (PubMed:31216475).
What are the official names of this protein?
Enhancer of rudimentary homolog 2.
What is the protein family that this protein belongs to?
Belongs to the E(R) family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Dispersedly distributes throughout the cytoplasm in early embryos (PubMed:31147388). During early embryogenesis, localizes to the nucleus at prophase of cell division, and remains in the cytosol at interphase in 2- and 4-cell embryos (PubMed:31216475). Localizes to puncta in the perinuclear region in the germline syncytium (PubMed:31216475, PubMed:31147388).
Protein: GLMS_LISMF
Sequence: MCGIVGYIGTNNAKSILLEGLEKLEYRGYDSAGIALQNKDLVTVVKEKGRIADLASLVPSDAFGTTGIGHTRWATHGKPNHENAHPHQSKSGRFTMVHNGVIENYTLLKEEYLKNHSFVSDTDTEVIVQLIELFAAELSTKEAFKKALSLLHGSYAICLIDQTDTETLYAAKNKSPLLIGKGENFNVIASDAMAVLKETDEFVEIMDKEIVIVTKDGFTLETLEGEEISRASYTAELDASDIEKGTYPHYMLKEIDEQPAVTRKIIQAYQNEAGEINVDQTILDEILSSDRIHIVACGTSYHAGLVGKNLIEKMAKIPVEVHVSSEFGYNLPLMSKKPLFIFITQSGETADSRQCLVKVKELGYRTLTLTNVPGSTLDREADHSMYLYAGPEIAVASTKAYTAQISVLAVLAVSLGREIGDAEALSINLAAELGIVATAMEAMVSSKEVIEHIAGEYLATSRNAFFLGRNIDYFVAMEAALKLKEISYIQAEGFASGELKHGTIALIEDGTPVLALITQESINWNIRGNVNEVLARGAKTCVFAMENVAQPGDRFVIPQVHPLLTPLASVIPCQLLAYYAALHRDCDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_AGRFC
Sequence: MTVQNDNRPLLRLVRLANGADLELPSYETRGAAGMDLRAAVPADEPLNLQPGERALVPTGFIFEVPQGYEAQIRPRSGLAIKNGITCLNSPGTVDSDYRGEVKVILANLGQDDFTIERGMRIAQMVIAPVTQVTVSEVTETSETARGAGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: MIC60_LACTC
Sequence: MLRSRATINCVKSGRAGRALSRGMATFEGQPAARPNRLSKLLVRVGLATVGFYVGGVTLSLNNDQFGELFCDNVPLAESLVEMYEEFRDEKMQASRMSLDELKQKFGELGTKVDRIPNRGADPALTSQAVAALPASKEVRLEDESLVKLRLPEVEQLGSCKRATPLVESVNAAVAAVNEQSLLLPEDTYNAVHDAFTKLKSALQAINEDIRTNVAESVAVQYGQASKDLHESFEIRAKSREVELTQQFLNEFNAFKAQLEKHSSEELASALKANEQALLAKQSNEVALLSMKQVEEFTKILSEKLDQERQGRLSKLEALNGSVQELAEAVDQVDTLVMKSEVLSQLSLLTTLLKNKLHAGDESSVKIDSELARLKTLCDILPGRPSKCCSKNPQLLDVVVSQLDSLASQQLILSNEQLYNRWTLLQKDLSTSSLLPPNAGILGHISAKIFGFFLFNKNGAPVDNDIDSVIARVGQNLRLSKLDKAVEEVVALKGWPRVLCDEWVQEARKKLEIETLIDALDCEIRSS
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.