PharMolix/UniProtQA huggingface dataset:
Protein: TRMD_STRPQ
Sequence: MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKARHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEELIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSHQDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLLERYDFSEEERKLLDKIKEALGQGED
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABHD8_HUMAN
Sequence: MLTGVTDGIFCCLLGTPPNAVGPLESVESSDGYTFVEVKPGRVLRVKHAGPAPAAAPPPPSSASSDAAQGDLSGLVRCQRRITVYRNGRLLVENLGRAPRADLLHGQNGSGEPPAALEVELADPAGSDGRLAPGSAGSGSGSGSGGRRRRARRPKRTIHIDCEKRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSFCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLECPETVNTLLHEFLLWEPEPSPKALPEPLPAPPEDKK
What are the official names of this protein?
Protein ABHD8, Alpha/beta hydrolase domain-containing protein 8, Abhydrolase domain-containing protein 8.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: Y1145_YERE8
Sequence: MHWLADYWWVVLIILVGMILNGIKELRRLDHKKFLSNKPEIPPHRDNNAQWDDDDDWPDKDKKK
What are the official names of this protein?
UPF0370 protein YE1145.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HXC10_PONPY
Sequence: MTCPRNVTPNSYSEXLAAPGGEERYSRSAGMYMXXGSDFXCGVMRGCGLAPSLSKRXXGGSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSYYRASPNYSALDKTPHCSGANDFEAPFEQRASLNPRTEHLESPQLGGKVSFPETPKSDSQTPSPNEIKTEQSLAGAKGSPSESEKERAKTADSSPDTSDNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C10.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAA_BURMS
Sequence: MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDAAANTLSIAAPNRFKLDWVKSQFSGRISDLARDFWNAPIEVQFVLDPKAGQRSPAGATPLAPRAPLPSANPAPVAPGPACAPAVDAHAPAPAGMNAATAAAVAAAQAAQAAQANAAALNADEAADLDLPSLTAHEAAAGRRTWRPGAANANSEAADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLYGGVGLGKTHLIHAIGNQLLLDKPGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEGVSLSEDVAFFVAKHLRSNVRELEGALRKILAYSKFHGREITIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERGKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPAT_PROMS
Sequence: MVQVNENYLKLKAGYLFPEIAKRVKLYSQSNKNAEIIKLGIGDVTEPLPRACIEAMGKALDDMGTTDGFRGYGPEQGYAWLREKISEHDFISRGCQISPEEIFVSDGSKCDSSNILDILGKDNSIAVTDPVYPVYVDSNVMTGRTGDALENGTYQGLTYLAINEANNFLPELPEKKVDILYLCFPNNPTGATINKEELKKWVDYALQNKSLILFDAAYEAFIQDNDIPHSIYEIEGAKDCAIEFRSFSKNAGFTGVRCAFTVIPKNLKGLSSTNEEIELWPLWNRRQSTKFNGVSYVVQKGAEAVYSLEGKKQVRGLIDFYMENAKIMKNKLQNSGYKVYGGDNAPYIWIKVPDQMTSWDFFDFLLQKVSVVGTPGSGFGLAGEGYFRLSAFNSRSNVIDAMERIINI
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: ULAD_ECO55
Sequence: MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: AQR_HUMAN
Sequence: MAAPAQPKKIVAPTVSQINAEFVTQLACKYWAPHIKKKSPFDIKVIEDIYEKEIVKSRFAIRKIMLLEFSQYLENYLWMNYSPEVSSKAYLMSICCMVNEKFRENVPAWEIFKKKPDHFPFFFKHILKAALAETDGEFSLHEQTVLLLFLDHCFNSLEVDLIRSQVQQLISLPMWMGLQLARLELELKKTPKLRKFWNLIKKNDEKMDPEAREQAYQERRFLSQLIQKFISVLKSVPLSEPVTMDKVHYCERFIELMIDLEALLPTRRWFNTILDDSHLLVHCYLSNLVRREEDGHLFSQLLDMLKFYTGFEINDQTGNALTENEMTTIHYDRITSLQRAAFAHFPELYDFALSNVAEVDTRESLVKFFGPLSSNTLHQVASYLCLLPTLPKNEDTTFDKEFLLELLVSRHERRISQIQQLNQMPLYPTEKIIWDENIVPTEYYSGEGCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDSVSRMKPWQSEYGGVVFGGWARMAQPIVAFTVVEVAKPNIGENWPTRVRADVTINLNVRDHIKDEWEGLRKHDVCFLITVRPTKPYGTKFDRRRPFIEQVGLVYVRGCEIQGMLDDKGRVIEDGPEPRPNLRGESRTFRVFLDPNQYQQDMTNTIQNGAEDVYETFNIIMRRKPKENNFKAVLETIRNLMNTDCVVPDWLHDIILGYGDPSSAHYSKMPNQIATLDFNDTFLSIEHLKASFPGHNVKVTVEDPALQIPPFRITFPVRSGKGKKRKDADVEDEDTEEAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEELETEKDFSRYGRVNYVLARRIELLEEVKRLQKSLGVPGDASYTCETAGYFFLYQVMSRWEEYISKVKNKGSTLPDVTEVSTFFPFHEYFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRSGLDRSKYLLVKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLYNWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTTRKNGERPSHEVQIIKNMPQMANFVYNMYMHLIQTTHHYHQTLLQLPPAMVEEGEEVQNQETELETEEEAMTVQADIIPSPTDTSCRQETPAFQTDTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:25599396, PubMed:28502770, PubMed:28076346).  Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis (PubMed:16949364).  Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly (PubMed:16949364).  May act by helping the folding of the snoRNA sequence.  Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing (PubMed:16949364).  Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro) (PubMed:25599396).
What are the official names of this protein?
RNA helicase aquarius, Intron-binding protein of 160 kDa, IBP160.
What is the protein family that this protein belongs to?
Belongs to the CWF11 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Note=Localizes to speckle-like regions of the nucleoplasm.
Protein: DTXR_COREF
Sequence: MKDLVDTTEMYLRTIYELEEEGIVPLRARIAERLEQSGPTVSQTVARMERDGLVHVSPDRSLEMTPEGRALAIAVMRKHRLAERLLTDIIGLDIHKVHDEACRWEHVMSDEVERRLVEVLDDVTRSPFGNPIPGLADIGLDQDREPDSGIRAIDLPHGESLRVRIVQLNEILQVDQEQFSILSSAGIRIGTEVDIINEQGRVVITHNGMMVELMDDLAHAVRVEKVDGLN
What is the function of this protein?
Iron-binding repressor of the dipheteria toxin gene expression.  May serve as a global regulator of gene expression.  Represses ripA under iron excess (By similarity).
What are the official names of this protein?
Diphtheria toxin repressor, Iron-dependent diphtheria tox regulatory element, Tox regulatory factor.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG5_EMENI
Sequence: MEKATLNSIQKSVWEGQIPLKIVLAPSESRTYDQTDPYLISYPRISYLPSLLPRLKAFFSSSLIDPTASQPHDGWFSFEGVPLKWHYPVGLLYDLYAGAEPATKSSETEALDDEQLPWRLVVHFGDWPDAELVRLDAQGTVMHDAFINSVKEADFVRNGTAKGIMTLSKDDSSGLWKAVQDVDLPSFQRIMNILLPPNPHQPLRNLPVRLFLPLPPKPDSNSDSPFLKVVQSPIPPTISTTPSQLQRQMAQSTLSSSGVSGSSPGAAQPQPQTQTIGTALHSILPNLFPSRRTPVIAKPVLHGAQVPMSAPVEEVVRAAAYGDGWVYIVIRMMG
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function.  The atg12-atg5 conjugate acts as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: RS16_BURO0
Sequence: MVIIRLARGGSKKRPFYNIVATDSRNRRDGRFIERVGFYNPVATKGESLRIAQDRLTYWQGVGAQLSPTVQRLVKEAQKAQPAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NSP3_ROTH6
Sequence: MLKMESTQQMVSSIINSSFEAAVVAATSTLELMGIQYDYNEVYTRVKSKFDLVMDDSGVKNNLMGKAATIDQALNGKFSSSIRNRNWMTDSKTDARLDEDVNKLRLLLSSKGIDQKMRVLNACFNVKRIPGKSSSVIRCTRLMKEKIERGEVEVDDAFVEEKMEVDTIDWKSRYEQLEKRFESLKQRVNEKYNNWVIKARKDNENMYSLQNVISQQQAHINELQIYNNKLERDLQSKIGSVISSIEWYLRSMELSDDIKSDIEQQLNSIDQINPVNAYDDFESILRNLISDYDRMFIMFKGLLQQSNYIYTYE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: DERI2_MYCS2
Sequence: MALKIVIGGDNAGFNYKEALRKDLEADDRVASVEDVGVGGVDDTTSYPNVAVAAAEKVARGEADRALLICGTGLGVAIAANKVKGIRAVTAHDVYSVQRSVLSNNAQVLCMGERVVGLELARALVKEWLGLEFDPQSASAAKVNDICAYEGA
What is the function of this protein?
Catalyzes the isomerization of D-erythrulose-4P to D-erythrose-4P.  Involved in the degradation pathways of L-threitol, D-threitol and erythritol, that allow M. smegmatis to grow on these compounds as the sole carbon source.
What are the official names of this protein?
D-erythrulose-4-phosphate isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: Y924_METJA
Sequence: MDYRWIQMKVITFSIAKGGTGKTIITANAAAALAKKGKKILLIDGDVGSKSLSHLLNVKSNIFLADIIEEERPIKDAIVNTPIENIELLAVGKSLADYLKFDINILKRFKELGDYDYVFIDAPSTSSGVETYLALGLSDYFIPVLDYTAFGPSLQGAINTIVIGKNYLESTPAGFIINKAEDLPESVINDIKKILGLECISIIHKNSLVEQSYAKKEIVYLTSSDKKFVEEIDKIVDALEKLKEVKERDIPKVIEKIKESTLL
What are the official names of this protein?
Uncharacterized ATP-binding protein MJ0924.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0547 and MJ0169.
Protein: PRP1_HUMAN
Sequence: MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSQSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSQSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPQQGGNRPQGPPPPGKPQGPPPQGDKSRSPQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ
What are the official names of this protein?
Basic salivary proline-rich protein 1, Salivary proline-rich protein.
What are the subcellular locations of this protein?
Secreted.
Protein: PURQ_BRADU
Sequence: MKAAILVFPGINRDRDMARALRLISGSEPAMVWHAETSLPAGTDLVVVPGGFSYGDYLRCGAIAARAPVMDAVRDYAAKGGLVLGVCNGFQILCESGLLPGVLMRNAQLKFICRDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGNYEADEETIQRLEGEGRVLYRYCSAEGVVDEAANINGAAHSIAGIVNDKGNVLGMMPHPENHVEDIMGCTDGRGLFAGLAQHLEKAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_LEGPH
Sequence: MTMDALSRLVEALRCLPGVGPKSAQRMVFHLLQHQRQRGLHLASCLEQAMKHISHCQQCNNYTEQTLCALCQNPNRDSTLLCVVESPADVSAIEQSNSFQGKYFVLMGKISPLDGLGPDDIGLPKLKELITREKIQEVILALSPSVESQTTIHFIHQLLKDETVNISQLAHGIPSGGELEFLDGNTISSALKNRAVINV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: GLF1_KLEPN
Sequence: MKSKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARDSETNVMVHVYGPHIFHTDNETVWNYVNKHAEMMPYVNRVKATVNGQVFSLPINLHTINQFFSKTCSPDEARALIAEKGDSTIADPQTFEEQALRFIGKELYEAFFKGYTIKQWGMQPSELPASILKRLPVRFNYDDNYFNHKFQGMPKCGYTQMIKSILNHENIKVDLQREFIVEERTHYDHVFYSGPLDAFYGYQYGRLGYRTLDFKKFTYQGDYQGCAVMNYCSVDVPYTRITEHKYFSPWEQHDGSVCYKEYSRACEENDIPYYPIRQMGEMALLEKYLSLAENETNITFVGRLGTYRYLDMDVTIAEALKTAEVYLNSLTENQPMPVFTVSVR
What is the function of this protein?
Involved in the biosynthesis of the galactose-containing O-side-chain polysaccharide backbone structure of D-galactan I which is a key component of lipopolysaccharide (LPS).  Catalyzes the interconversion through a 2-keto intermediate of uridine diphosphogalactopyranose (UDP-GalP) into uridine diphosphogalactofuranose (UDP-GalF) which is the biosynthetic precursor of galactofuranosyl residues.
What are the official names of this protein?
UDP-galactopyranose mutase, UGM, UDP-GALP mutase, Uridine 5-diphosphate galactopyranose mutase.
What is the protein family that this protein belongs to?
Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.
Protein: PHK_CHLTE
Sequence: MTEMTTPLSPRELDLMNAYWRAANYLSVGQIYLMDNPLLKEPLSKEHIKPRLLGHWGTTPGLNFLYVHLNRIIRNRDLDIIYIAGPGHGGPALVANVWLEGTYSEYYPDVSFDEAGMKRLFRQFSFPGGIPSHVAPATPGSIHEGGELGYALSHAYGAVFDNPDLVAACVIGDGEAETGPLATAWHSNKFLNPKRDGAVLPVLHLNGYKIANPTVLARISHEELEQLMIGYGYKPYFVEGDDPATMHQMMAATMDRCFDEIAEIQRRARVDGVTERPMWPMIVFRSPKGWTGPKVVDGKPAEGSWRSHQVPFSTVRDNPEHMALLETWLKSYRAEELFTADGVLLPELQELAPRGKKRMGDIPHANGGLLLKELRMPDFREYGIDVPKPGSVEAEAPKPMARFLRDIMKMNEKAANFRVFGPDETASNRLGELFEETDRTWMAGMLPTDDHLSRDGRVMEILSEHTCQGWLEGYLLTGRHGFFSCYEAFIHIIDSMFNQHAKWLKVTGAEIPWRRPIASLNYFLTSHVWRQDHNGFSHQDPGFIDHVVNKKSSVIRVYLPPDANSLLSVTNHCLRSRNYINVIVAGKQPAWQWLDMESAVRHCTSGIGIWEWASNDANEGEPDVVMACAGDVPTLETLAAVKILRKLAPELKIRVVNVVDLMTLQPKEEHPHGLADRDFDDMFTTDKPIIFAYHGYPWLIHRLTYRRTNHHNLHVRGYKEEGTTTTPFDMVVMNELDRFHLVADVANRVESLRPQAAYIKQYVRDRLIEHKEYITKYGEDMPEVRDWRWED
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: GLSA1_BACAN
Sequence: MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLDRGEEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLAGKDNEEKMERILHFVREITDNPTINYSSKVANSELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKKKQIIPKHITKICKTFMVTCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGEMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF
What are the official names of this protein?
Glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: KAD1_SYNY3
Sequence: MAMAKGLIFLGAPGSGKGTQAVGLAETLGIPHISTGDMLRQAIADGTELGNQAKGYMDKGELVPDQLILGLIEERLGHKDAKAGWILDGFPRNVNQAIFLDELLVNIGHRTHWVINLKVPDEVIVERLLARGRADDNETTIRNRLLVYTEQTAPLMAYYQEQGKLYSLDGNQPVEAIATNLEKLVKP
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase 1, AK 1, ATP-AMP transphosphorylase 1, ATP:AMP phosphotransferase 1, Adenylate monophosphate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAD_RHILW
Sequence: MKKKAEWPRKLRSQEWYGGTSRDVIYHRGWLKNQGYPHDLFDGRPVIGILNTWSDMTPCNGHLRELAEKVKAGVWEAGGFPLEVPVFSASENTFRPTAMMYRNLAALAVEEAIRGQPMDGCVLLVGCDKTTPSLLMGAASCDLPSIVVTGGPMLNGYFRGERVGSGTHLWKFSEMVKAGEMTQAEFLEAEASMSRSSGTCNTMGTASTMASMAEALGMALSGNAAIPGVDSRRKVMAQLTGRRIVQMVKDDLKPSEIMTKQAFENAIRTNAAIGGSTNAVIHLLAIAGRVGIDLSLDDWDRCGRDVPTIVNLMPSGKYLMEEFFYAGGLPVVLKRLGEAGLLHKDALTVSGETVWDEVKDVVNWNEDVILPAEKALTSSGGIVVLRGNLAPKGAVLKPSAASPHLLVHKGRAVVFEDIDDYKAKINDDNLDIDENCIMVMKNCGPKGYPGMAEVGNMGLPPKVLKKGILDMVRISDARMSGTAYGTVVLHTSPEAAVGGPLAVVKNGDMIELDVPNRRLHLDISDEELARRLAEWQPNHDLPTSGYAFLHQQHVEGADTGADLDFLKGCRGNAVGKDSH
What is the function of this protein?
Catalyzes the dehydration of L-arabinonate to 2-dehydro-3-deoxy-L-arabinonate during L-arabinose degradation.  Can also dehydrate D-galactonate and D-fuconate with good catalytic efficiency.  Has weak activity with D-xylonate and D-gluconate.
What are the official names of this protein?
L-arabinonate dehydratase, ArDHT, D-fuconate dehydratase, Galactonate dehydratase, L-arabonate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: HNRPM_HUMAN
Sequence: MAAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA
What is the function of this protein?
Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro.  Involved in splicing.  Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein M, hnRNP M.
Protein: SCO1_YEAST
Sequence: MLKLSRSANLRLVQLPAARLSGNGAKLLTQRGFFTVTRLWQSNGKKPLSRVPVGGTPIKDNGKVREGSIEFSTGKAIALFLAVGGALSYFFNREKRRLETQKEAEANRGYGKPSLGGPFHLEDMYGNEFTEKNLLGKFSIIYFGFSNCPDICPDELDKLGLWLNTLSSKYGITLQPLFITCDPARDSPAVLKEYLSDFHPSILGLTGTFDEVKNACKKYRVYFSTPPNVKPGQDYLVDHSIFFYLMDPEGQFVDALGRNYDEKTGVDKIVEHVKSYVPAEQRAKQKEAWYSFLFK
What is the function of this protein?
Required for the accumulation of subunits 1 and 2 of cytochrome c oxidase complex.  Thought to play a role in either mitochondrial copper transport or insertion of copper into the active site of COX.
What are the official names of this protein?
Protein SCO1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: PUR9_MYCTO
Sequence: MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: LYSM1_HUMAN
Sequence: MASPSRQPPPGGSGLLQGSRARSYGSLVQSACSPVRERRLEHQLEPGDTLAGLALKYGVTMEQIKRANRLYTNDSIFLKKTLYIPILTEPRDLFNGLDSEEEKDGEEKVHPSNSEVWPHSTERKKQETGAGRANGEVLPTPGQETPTPIHDLSASDFLKKLDSQISLSKKAAAQKLKKGENGVPGEDAGLHLSSPWMQQRAVLGPVPLTRTSRTRTLRDQEDEIFKL
What are the official names of this protein?
LysM and putative peptidoglycan-binding domain-containing protein 1.
Protein: PG18_MYCTU
Sequence: MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAHDEVSTAIAALFGSHGQHYQAISAQVAAYQERFVLALSQASSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGGTGGTGGAVSLARAGTAGGAGGGPAGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDPVTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVIDPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
What is the function of this protein?
Expression in Mycobacterium smegmatis, a nonpathogenic species naturally deficient in PE_PGRS genes, results in alteration of the production of host cytokines, including IL-6, IL-1beta, IL-10 and IL-12p40, as well as enhanced survival within macrophages largely via attenuating the apoptosis of macrophages.
What are the official names of this protein?
PE-PGRS family protein PE_PGRS18.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Cell envelope-associated protein.