PharMolix/UniProtQA huggingface dataset:
Protein: PEPT_STRP2
Sequence: MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPEMKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDGCVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAHPEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAELHFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEARASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTPITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTMERAVDTIIGIVRSL
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET16_DICDI
Sequence: MSEIDTNDIKKEMDNKNYRDPTDNKELLKWTKKKRKRSNDSMHINNFYRYNPPNFKLLASKYPTFDKYIINKTEKIYNIDWKDSNATKELTRVLLDHDFGLRIELPDNYLCPTLTLRINYLYWISDQLKNLKIILNDNDNDNKIIKGIDIGTGTSCIFPLLGAKLFNNWSFIGIDIDDKVLEYAQNNITINSLNSKITLFKNEKNSDILLKLLNYKEGSNTFNSSNDDHQDNHDDDDDDEEYFADFCLCNPPFFKDLNENNNNKNNNPKSNCTGSVNEMVTDGGEFEFVKRIIKESFQLKCKIRFYTTMIGRKVNLNPLINILIKQYYLPKNQIQTTELVQGNTSRWVLSWYFLNKSTNLETKENNNINNNNNNNNNNNINNNNQFLTRMERRKLYREGITLNLDSDDNNNNNNNNNNNNNNNNNNNNNNNNNNNKIVEIIKLILDNNDIIYKTDENNIKYECKYLLNNVIVGSSIKLDRDIEFLFTIFIDLTTRLILFKPIDPKINNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNSCDGEIINSNLFFILKFLENIKNEIKLK
What is the function of this protein?
RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA).
What are the official names of this protein?
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
Protein: SCRB_SALTM
Sequence: MSLPSRLPAILQAVMQGQPRALADSHYPRWHHAPVTGLMNDPNGFIEFAGRYHLFYQWNPLACDHTFKCWAHWSSIDLLHWQHEPIALMPDEEYDRNGCYSGSAVDNNGTLTLCYTGNVKFAEGGRTAWQCLATENADGTFRKIGPVLPLPEGYTGHVRDPKVWRHEDLWYMVLGAQDRQKRGKVLLFSSADLHQWTSMGEIAGHGINGLDDVGYMWECPDLFPLGDQHILICCPQGIAREEECYLNTYPAVWMAGEFDYAAGAFRHGELHELDAGFEFYAPQTMLTSDGRRLLVGWMGVPEGEEMLQPTLNNGWIHQMTCLRELEFINGQLYQRPLRELSALRGEANGWSGNALPLAPMEIDLQTRGGDMLSLDFGGVLTLECDASGLRLARRSLASDEMHYRYWRGNVRSLRVFIDQSSVEIFINGGEGVMSSRYFPACSGQLTFSGITPDAFCYWPLRTCMVE
What is the function of this protein?
Enables the bacterium to metabolize sucrose as a sole carbon source.
What are the official names of this protein?
Sucrose-6-phosphate hydrolase, Sucrase, Invertase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LC_NANDO
Sequence: MMLEHVLVLSAYLLSIGIYGLITSRNMVRALMCLELILNAVNMNFVTFSDLFDSRQIKGDIFSIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSNLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL11_YERPN
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTESIEKGLPIPVVITVYSDRSFTFVTKTPPAAVLLKKAAGIKSGSGVPNKDKVGKVTSAQVREIAETKAADMTGSDVDAMMRSIEGTAHSMGLVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SRP19_METM7
Sequence: MKEMIIWPAYIDIKRTKNEGRKVPKEFAVANPKLKDIADKIKKMGLEHSIEIKKSYPMEPWEICGYIKVKLDKNTSKLQILKEISKNMK
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_XYLFM
Sequence: MSNILTKILARKVEEIAERLLHVSQAELVARCADLPTPRGFAAALQATIVHGDPAVIAEIKKASPSKGVLREDFRPAEIAISYELGGASCLSVLTDVHFFKGHDNYLSQARDACTLPVLRKDFTIDPYQVYEARVLGADCILLIVAALDDAQLVDLSGLALQLGMDVLVEVHDIDELERAIQISAPLIGINNRNLSTFNVSLETTLTMKGLVPRDRLLVSESGILTSADVQRLRAAGVNAFLVGEAFMRAAEPGESLREMFFIT
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: PYRKH_AQUAE
Sequence: MLAELNAEVLENTYISGNLYRLTLRIPDKILKQIEPGHFAMIKPSDTYDPMGRRAFAVADIEEHKAVFYYDVYGKGTYLLSKRKPGERLKTFLPLGKRLFSYEGDKHLLIGGGVGLAGLTLLAKKLRDMGKKVFIAYGGRSREHLGMVEWLEKEEFPYELFTNDGSAGRKGFVTEILKEFSTDWVVHACGPKPMLKTIKEMKTGHKVYFSLEERMACGWGVCLGCVVKTRDGKFKRVCYEGPVMPMEEVIL
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog, Dihydroorotate oxidase B, electron transfer subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: PP14A_RAT
Sequence: MAAQRLGKRVLSKLQSPSRARGPGGSPSGLQKRHARVTVKYDRRELQRRLDVEKWIDGRLEELYRGREADMPDEVNIDELLELDSEEERCRKIRGLLEACLNPTEDFVQELLAKLRGLHKQPGFPQPSPSDDPSLSPRQDPAHTAPP
What is the function of this protein?
Inhibitor of PPP1CA.  Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction (By similarity).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 14A, 17 kDa PKC-potentiated inhibitory protein of PP1, Protein kinase C-potentiated inhibitor protein of 17 kDa, CPI-17.
What is the protein family that this protein belongs to?
Belongs to the PP1 inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1221_NITHX
Sequence: MATAVAAKEEPATRFAKDQLKAIIERIERLEEEKKTLSDDIRDVYAEAKGNGYDVKALRTIVRMRKQDANERAEQETILETYMQALGML
What are the official names of this protein?
UPF0335 protein Nham_1221.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: RPPH_ALKEH
Sequence: MVDSDGFRPNVGIILANAAGQVFWARRIGQNAWQFPQGGIKAQETPEEALFRELEEEVGLAPADVEVMGCTRGWLRYRLPRRLIRSRSRPVCIGQKQVWFLLRLVGEEEQVQLDRSERPEFDHWRWVDFWHPVQEVVFFKRRVYTRALQELGPLLFPDGLPRQPPVGRPRRSAPPRGCRRA
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: CYSD_SHEHH
Sequence: MAAKELSHLQQLEAESIQIIREVAAEFDNPVMMYSIGKDSSVMLHLARKAFYPGKIPFPLLHVDTDWKFKEMIAFRDEQAKEFGFELLVHKNPEGLEMGISPFEHGSAKHTDIMKTQGLKQALNKYGFDAAFGGARRDEEKSRAKERVYSFRDKHHTWDPKNQRPELWRTYNGAVNKGESIRVFPLSNWTELDIWQYIYQENIQLVPLYFAQKRPVVERDGMMIMVDDDRMPLAEGEQPKQELVRFRTLGCYPLTGAMHSEADTLEKIIEEMLLTRSSERQGRLIDSDQSASMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: DCUP_HELPY
Sequence: MIFIDACFRKETPYTPIWMMRQAGRYLSEYQESRKKAGSFLELCKNSDLATEVTLQPVEILGVDAAILFSDILVVPLEMGLNLEFIPKKGPHFLETITDLKSVESLKVGAYKQLNYVYDTISQTRQKLSREKALIGFCGSPWTLATYMIEGEGSKSYAKSKKMLYSEPEVLKALLEKLSLELIEYLSLQIQAGVNAVMIFDSWASALEKEAYLKFSWDYLKKISKELKKRYAHIPVILFPKGIGAYLDSIDGEFDVFGVDWGTPLTAAKKILGGKYVLQGNLEPTRLYDKNALEEGVETILKVMGNQGHIFNLGHGMLPDLPRENAKYLVQLVHAKTRR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYRA_STAAN
Sequence: MTTVLFVGLGLIGGSLASNIKYHNPNTNIIAYDADTSQLDKAKSIGIINEKCLNYSEAIKKADVIIYATPVAITNKYLSELIDMPTKPGVIVSDTGSTKAMIQQHESNLLKHNIHLVSGHPMAGSHKSGVLNAKKHLFENAYYILVYNEPRNEQAANTLKELLSPTLAKFIVTTAEEHDYVTSVVSHLPHIVASSLVHVSQKNGQEHHLVNKLAAGGFRDITRIASSNAQMWKDITLSNKTYILEMIRQLKSQFQDLERLIESNDSEKLLSFFAQAKSYRDALPAKQLGGLNTAYDLYVDIPDESGMISKVTYIMSLHNISISNLRILEVREDIYGALKISFKNPTDRERGMQALSDFDCYIQ
What are the official names of this protein?
Prephenate dehydrogenase, PDH.
What is the protein family that this protein belongs to?
Belongs to the prephenate/arogenate dehydrogenase family.
Protein: NUOI_MYCS2
Sequence: MPKFLDALAGFAVTLGSMFKKPITEGYPEKPGPVAPRYHGRHQLNRYPDGLEKCIGCELCAWACPADAIYVEGADNTADERYSPGERYGRVYQINYLRCIGCGLCIEACPTRALTMTTEYEMADDNRADLIWGKDKLLAPLQEGMQAPPHDMAPGKTDDDYYLGNVTPITPVPSGTEDAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL9_RICB8
Sequence: MEVILIKPVRKLGKIGEIHKVADGFGRNYLLPQKLAIRATELNKELIVKQKHELEEKDKQIKSEITKINDLIKDQKLIFVRQTSDDGKLFGSVNNKEIAKKLSQAVSYPISHLNIILDTQIKSTGIYKVEVRLHAELSTEVTVIVARSESEIQDYLREQKTEKSTTEPLAESA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PYRF_YERE8
Sequence: MTSATKTNNSGSISSPIVVALDYANKDAALAFADRVNPRDCRLKVGKEMFTLYGPQLVRDLHQRGFEVFLDLKFHDIPNTTARAVAAAAELGVWMVNVHATGGMRMMTAAKEALLPFGQQAPLLIAVTVLTSMDGGDLRDIGINITPAEQAERLAKLTWDCGLDGVVCSAHEAVRLKQVCGEDFKLVTPGIRPEGSDAGDQRRIMTPEQAVAAGVDYMVIGRPITQSPDPEKTLKDILASLCKGAK
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: HPRK_STAAT
Sequence: MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: DNJ11_ARATH
Sequence: MLSSSPTSFTHPFLSSSPPLSPISPPSRTARISPPLVSASCSYTYTEDSPRLHQIPRRLTTVPASLYDVLEVPLGATSQDIKSAYRRLARICHPDVAGTDRTSSSSADEFMKIHAAYCTLSDPEKRSVYDRRMLRRSRPLTVGTSGLGSYVGRNWETDQCW
What is the function of this protein?
Plays a continuous role in plant development probably in the structural organization of compartments.
What are the official names of this protein?
Chaperone protein dnaJ 11, chloroplastic, AtDjC11, AtJ11.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family. C/III subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Note=Probably also in other plastids.
Protein: PYRE_HELPY
Sequence: MDIKACYQNAKALLEGHFLLSSGFHSNYYLQSAKVLEDPKLAEQLALELAKQIQEAHLNIECVCSPAIGGILAGYELARALGVRFIFTERVDNTMALRRGFEVKKNEKILVCEDIITTGKSAMECAKVLEEKGAQIVAFGALANRGICKRAHSHLKAQEGACLPSHLPLFALEDFVFDMHKPSSCPLCATSVAIKPGSRGN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RS8_HERAR
Sequence: MSMSDPIADMLTRIRNAQVVQKTSVAMPSSKVKIAIANVLKDEGYIEDYAVTEAAGKAELKIGLKYYAGRPVIERLERVSRPGLRVYKGKDDIPNVMNGLGVAIVSTPKGVMTDRKARATGVGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RM17_PONAB
Sequence: MRLSVCAAISHGRVFRRMGLGPESRIHLLRNLLTGLVRHERIEAPWARVDEMRGYAEKLIDYGKLGDTNERAMRMADFWLTEKDLIPKLFQVLAPRYKDQNGGYTRMRQIPNRSLDRAKMAVIEYKGNCLPPLPLPRRDSHLTLLNQLLQGLRQDLSQSQEASNHSSHTAQTPGI
What are the official names of this protein?
39S ribosomal protein L17, mitochondrial, L17mt, MRP-L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CAMT1_TOBAC
Sequence: MATNGRHQEVGHKSLLQSDALYQYILETSVYPREPEPMKELREITAKHPWNLMTTSADEGQFLSMLIKLINAKNTMEIGVFTGYSLLATAMALPDDGKILAMDINRENYEIGLPVIEKAGLAHKIEFKEGPALPVLDQMIEDGKYHGSYDFIFVDADKDNYLNYHKRLIDLVKIGGLIGYDNTLWNGSVVAPPDAPLRKYVRYYRDFVLELNKALAADSRIEICQLPVGDGITLCRRIS
What is the function of this protein?
Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA.  Plays a role in the synthesis of feruloylated polysaccharides.  Involved in the reinforcement of the plant cell wall.  Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers.
What are the official names of this protein?
Caffeoyl-CoA O-methyltransferase 1, Trans-caffeoyl-CoA 3-O-methyltransferase 1, CCoAMT-1, CCoAOMT-1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
Protein: MTNB_BACAA
Sequence: MKQLFRQWYDLSEIKKELTTRNWFPATSGNISIKVSHEPLTFLITASGKDKTKTTPDDFLLVDHLGVPVLETELRPSAETILHTHIYNNTNAGCVLHVHTTDNNVITNLYSDAVTLQNQEIIKALDIWEEGATIHIPIIENHAHIPTLGENFRKHIQGDSGAVLIRNHGITVWGRDSFDAKKRLEAYEFLFQFHIKLLSIQGGVSNGANSYS
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: ARCSA_METAC
Sequence: MTQYFEIENRDGAARIGKLLLFPEIRTPCALHTAALGDLENPGPIVDAGSLWIADQKELEARIKEIREKTGKGTLIILPHQTYPPAVPAESTGKVEAFTATGDENAEAEGPTGSLLRAEGEVRKSDLYIMEGAGTLENNARRFLETLIDLKNRIPPDTALYAPKLALPENAAMLAYVGIDVMDDTRAEIAAYSDIYLTAAGSFYLDSLVEFPCRCRVCAATTPAELRALPKADRVELLSAHNRDALDAELALVREKIRTGNLREYVEGQCRVRPWLTALLRLGDFEYSYIEEKVPAFRQSQLLADTSEALSRIEVVRFARRIQERYAPPDLDVLLLLPCAARKPYSTSQSHQKFILALGKYRKFVHEVIITSPLGIVPRELELTYPAAHYDTAVTGHWDEEEKAWVSGCLESYLSKHMYKAVVAHVEGAYREICERVAEKLGIDVVYTAGESLASYESLTNLKNTVEAICTSKDFSRKSQNAEKEKKNFIKAVAGYQFGEGAGHLFSEEVGDPLVKGRFPKYQLFAGKKQLATLIPQYGMLALSPEGAELVLKSEKYVVKIDDFVPRGSILAPGVLDAGPEIRPNDEVIVLGKKALCVGRAMMSGREMKESGRGVAVDVRHVKKL
What is the function of this protein?
Functions in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNAs.  Catalyzes the addition of L-lysine to the cyano group of 7-cyano-7-deazaguanine (preQ0)-modified tRNAs at position 15, to generate q0kN15-tRNA, a q0N lysine adduct identified as 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine.
What are the official names of this protein?
Archaeosine synthase subunit alpha, Archaeosine synthase, lysine transferase subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeosine synthase type 1 family.
Protein: RS14_NEIG1
Sequence: MAKKALINRDLKRQALAKKYAAKRAAIKAVINDSNATEEERFEARLRFQSIPRNAAPVRQRRRCALTGRPRGTFRKFGLGRIKIREIAMRGEIPGVVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RS3A_GIAIC
Sequence: MAIGGNKTGKKKITQRKNPDPYLKKEWYPVIAPAHFKSRHIGQTPVTKTAGLRVATDVINHRVYEVNLGDLNPGAEDLNGNTKFYLQTQLVSDGKCLTNFHGMDITRHKYGSLFRKGCDCIDVFMDIPTTDGYLLRVFVIAFTDRFRFQRRKNCHVKGRVIRMMRAGIYETLHNELGKVSIPVLVTKLSNFEVNAKLTEALQKITMCRDVMIRRVKVVKRPRNTMELLSTMHDSNQVRNLAEGQSIQQ
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXRBN_MYCTU
Sequence: MRYFYDTEFIEDGHTIELISIGVVAEDGREYYAVSTEFDPERAGSWVRTHVLPKLPPPASQLWRSRQQIRLDLEEFLRIDGTDSIELWAWVGAYDHVALCQLWGPMTALPPTVPRFTRELRQLWEDRGCPRMPPRPRDVHDALVDARDQLRRFRLITSTDDAGRGAAR
What is the function of this protein?
Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.  Has no activity with 5' overhangs.  Has negligible endonuclease activity.  Can bind ATP, dATP and AMP (in vitro); the nucleotide occupies the predicted substrate binding site.
What are the official names of this protein?
3'-5' exoribonuclease Rv2179c.
Protein: ATP6_EDWI9
Sequence: MSAGEISTPQEYIGHHLNNLQLDLRTFELVNPHDGPASFWTLNIDSMFFSVVLGLIFLALFRKVAKNATSGVPGKFQTAVELIIGFVDGSVRDMYHGKSKLIAPLALTIFVWVFLMNLMDLVPIDFLPYIAEHWMGLPALRVVPSADVNITLSMALGVFILILFYSIKMKGVGGFVKELTLQPFNHPVFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWLLNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYR_CAUSK
Sequence: MSDLKRSLSEAAAAAFQAAGLSPDFGRVTASDRPDLADFQCNGALAAAKSAKRNPREIAVQVVDVLKADPRLASVEIAGVGFINMRVSTDALSIRANEIAADPRAGAEPLAHPRRVLVDYAGPNVAKPMHVGHLRASIIGESVKRLYRFRGDDVVGDAHFGDWGFQMGLLISAIMEEDAFIRALLERLVEAPREFSKADEDKVMSEFAQRVTLDDLDRLYPAASARQKEDPEFKEKARKATAELQNGRFGYRLLWRHFVNISRVALEREFHALGVDFDLWKGESDVQDLIAPMVRQLEVKGLLVDDQGARIVRVARPGETKKKKLPDGSVVEVESPDPLLVVSSEGSAMYGTTDLATILDRRKSFDPHLILYCVDQRQADHFEQVFRAAYLAGYAEPGSLEHIGFGTMNGSDGKPFKTRAGGVLKLHDLIEMAREKARERLREAGLGAELSQEAFEETAHKVGIAALKFADLQNFRGTSYVFDLDRFTSFEGKTGPYLLYQSVRIKSILRKAAEQKVVSGAIIVGEPAERDLTLLLDAFEGALSEAYDKKAPNFIAEHAYKLAQTFSKFYAACPILSADNDATRASRLALAETTLKQLELALDLLGIEAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_STRP8
Sequence: MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSIGGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIRLTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: KCY_CALS8
Sequence: MKKINIAIDGPAGAGKSTISKLLAKKLGYIHIDTGAMYRAIGLKVLNSNIKSNEVEKILEVLDNTDIQIKIVAGSQLVLLDGEDVTEKIRQPSVSMYASDVSKIKEVREKLVKIQQDLAKQKGVIMDGRDIGTYVLPDAELKIFLTATAEERAKRRFLELKEKGYEVDYYQLLDEIKQRDLNDMTRELAPLRVAEDAIVIDSTNLTIEEVLQKVLELFYKVIGNEV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.