Protein: ANR11_MOUSE
Sequence: MPKGGCSKTPQQEDFALSNDMVEKQTGKKDKDKVSLTKTPKLDRSDGGKEVRERATKRKLPFTVGANGEQKDSDTEKQGPERKRIKKEPVARKSGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQKTVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKEAKANSFISIPKMEVKSYSKNNTLAPKKAAHRILSDTSDEEDVSVSIGAGEKLRLSAHTMLPGSKARESSSSRQQKEKNKLKKKRKKETKGKEVRFGKRSDKFCSSGSESESSESEEDDGDSVGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSAVAQKHGSGHTDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESDCSSEGSSVESLKPTRRKQEHRKRGVLQSAPSEKRSSFHPCTDGAVPKLDKEGKVVKKHKTKHKHKHKEKGQCSVSQELKLKSFTYEYEDSKQKSDKAILLESDLSTENKLKVLKHDREHLKKEDKLGRMKPEDKDWLFKDEKVLKRIKDANKDMSRAFREDKDRASKAERERATKDKSPKEEKLRLYKEERKKKSKDRASRLERKNDMKEDKLSKEKEKAFKEDKEKLKKEKLYREDAAFDDYCNKSQFLDHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSVTDYRDIKNDSVAKLILETVKEDSKEKKRDNKIREKRDFKDSFFRKRDRDCLDKNSEKRRDQTEKHKSIPSYLSEKDKKRRESAEGGRDRRDGRIRSEEVHREDLKECGFESSFKDKSDCDFPKNLEPWERPHAAREKEKKDALEKERKEKGRADKYKEKSSERERSDKSTLDKCQKDKEFEKCFKEKKDGKEKHKDIHSKDRKASFDQLREKKEKVFSSIISEDFSERKDDRKGKEKSWYIADIFTDESEDEKDDCVAGSFKATEASDTQRVDGLPEKEEGREHPSDRHRKSSSDRQHTEKPRDKEPKEKKKDRGASEGGKDKKEKMEKIFEKHKEKKDKECAERYKDRKERASADSAPEKKNKQKLPEKVEKKHFAEDKVKSKHKEKPEKEHSRERERKPSRGPDVEKSLLEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPAEDKARDSACLSEKLREKERHRHSSSSSKKSHERERAKKEKAEKKEKSEDYKDSISSVRKDASQFEKDFLDAETYGVSYPTKADVEEELDKAIELFSSEKKDRSDPEREPAKRIEKELKPYGSSAISILKEKKKREKHRERWREEKERHRDKHVDGFLRHHKDEPKPAAKDKDNPPNSFKEKSREESLKLSETKLKEKFKENTEREKGDSIKMSNGNDKLVPSRDSGKKDSRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEKKPTEDGRKKSLDFPSKKALGLDKKVKEPAPTLTTGESKPHSGPGTESKDWLSGQPLKEVLPASPRTEQSRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTASTSACSPPFFDRFSVASSVVSENAAGQTPTRPISTNLYRSISVDIRRTPEEEFSAGDKLFRQQSVPAPSSFDSPVQHLLEEKAPLPPVPAEKFACLSPGYYSPDYGIPSPKVDTLHCPPTAVVSATPPPDSVFSNLPPKSSPSPRGELLSPAIEGTLPPDLGLPLDATEDQQATAAILPQEPSYLEPLDEGPFTTVITEEPVEWTHTAAEQGLSSSSLIASASENPVSWPVGSELMLKSPQRFAESPKHFCPGESLHSTTPGPYSAAEPTYPVSPGSYPLPAPEPALEEVKDGGTGAIPVAISAAEGAAPYAAPARLESFFSNCKSHPDAPLDTAPEPTGVTAVAQVEALGPLESSFLDSNPSISTLSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAEAAKASPVPPAESPPGPTGVLGGGDVPAPAAEEPPAPPPQEASPQLSTEPEPSEEPKLDVVLEATVETEVLADDSAPEASISNSVPAPSPPQQQPPGGGDEEAETEDPSATPCCAPDGPTTDGLAQAHNSAEASCVVAAAEGPPGNVQAEATDPEPKPTSEVPKAPKVEEVPQRMTRNRAQMLASQSKQGIPAAEKDPMPTPASRAKGRASEEEDAQAQHPRKRRFQRSSQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA
What is the function of this protein?
Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells (PubMed:25556659).  May recruit histone deacetylases (HDACs) to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation (By similarity).  Has a role in proliferation and development of cortical neural precursors (PubMed:25556659).  May also regulate bone homeostasis (PubMed:17986521).
What are the official names of this protein?
Ankyrin repeat domain-containing protein 11.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to chromatin during prometaphase (By similarity).