PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_BRASB
Sequence: MVTIVDTLSNTPLRPRHPEKANRPDSISPAKPSWIRVKAPTTRGYADTRNIVRENGLVTVCEEAGCPNIGECWDKKHATFMIMGDTCTRACAFCNVKTGLPAALDAGEPEHVAEATFKLGLAHVVVTSVDRDDLADGGAAHIAATIRAIRATCPTTTIEVLTPDFLRKDGALEQVVAAKPDVFNHNLETVPSRYLSVRPGARYFHSIRLLQRVKEIDPTIFTKSGIMVGLGEQRHEVLQVMDDLRSAEVDFLTIGQYLQPTKKHHAVMAYVTPEEFSNYETVAYTKGFLMVSASPLTRSSHHAGEDFAKLKAARDALAR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_BORA1
Sequence: MSQRKYFGTDGVRGEVGGPVINAAFALRLGYAAGRVLVRRNASRQGGRPQVLIGKDTRISGYMLESALEAGLSAAGIDVVLAGPIPTPGVAYLTRALRLVAGIVISASHNPYQDNGIKFFSAEGTKLPDEVEAEIEAALEQELGCVKSEDLGRARRMSDSQGRYIEFCKSTVPHSLDLHGMKLVVDAANGAAYHIAPHVFRELGAEVYAIGVSPDGFNINKGVGALHPESLAEEVKARGAHYGIALDGDADRLQMVDASGRIYNGDELLYAIVRDRMRQGKVEGVVGTLMTNYGFELAMGRLGVAFERANVGDRYVLEQLLARGWQFGGESSGHLLCLDCHTTGDGTIAALQVLAALHANKASLSDWIADLRLYPQVMINVPLQPGQDWKTHAGLAAARAGVEAELAGRGRVLIRASGTEPKLRLMVEAEDFALAQASAQKLADSLG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MK10_HUMAN
Sequence: MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
What is the function of this protein?
Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death.  Extracellular stimuli such as pro-inflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway.  In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3.  In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity.  Plays regulatory roles in the signaling pathways during neuronal apoptosis.  Phosphorylates the neuronal microtubule regulator STMN2.  Acts in the regulation of the amyloid-beta precursor protein/APP signaling during neuronal differentiation by phosphorylating APP.  Participates also in neurite growth in spiral ganglion neurons.  Phosphorylates the CLOCK-BMAL1 heterodimer and plays a role in the photic regulation of the circadian clock (PubMed:22441692).  Phosphorylates JUND and this phosphorylation is inhibited in the presence of MEN1 (PubMed:22327296).
What are the official names of this protein?
Mitogen-activated protein kinase 10, MAP kinase 10, MAPK 10, MAP kinase p49 3F12, Stress-activated protein kinase 1b, SAPK1b, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor. Nucleus. Mitochondrion. Note=Palmitoylation regulates MAPK10 trafficking to cytoskeleton. Recruited to the mitochondria in the presence of SARM1 (By similarity).
Protein: METAA_THEMA
Sequence: MPINVPSGLPAVKVLAKEGIFVMTEKRAIHQDIRPLEILILNLMPDKIKTEIQLLRLLGNTPLQVNVTLLYTETHKPKHTPIEHILKFYTTFSAVKDRKFDGFIITGAPVELLPFEEVDYWEELTEIMEWSRHNVYSTMFICWAAQAGLYYFYGIPKYELPQKLSGVYKHRVAKDSVLFRGHDDFFWAPHSRYTEVKKEDIDKVPELEILAESDEAGVYVVANKSERQIFVTGHPEYDRYTLRDEYYRDIGRNLKVPIPANYFPNDDPTKTPILTWWSHAHLFFSNWLNYCIYQKTPYRLEDIH
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.  Utilizes a ping-pong kinetic mechanism in which the acetyl group of acetyl-CoA is initially transferred to the enzyme to form an acetyl-enzyme intermediate before subsequent transfer to homoserine to form the final product, O-acetylhomoserine.  Has weak activity with succinyl-CoA as the acyl donor.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, HTS-like HTA, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DB126_PANTR
Sequence: MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPGEMHIKNGWATCGKQRDCCVPADRRANYPAFCVQTKTTRTSTVTAKTTLMVTTASMSSMAPTPVSPTG
What is the function of this protein?
Highly glycosylated atypical beta-defensin involved in several aspects of sperm function.  Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx.  Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation.  Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte.  In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (By similarity).
What are the official names of this protein?
Beta-defensin 126, Defensin, beta 126.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted by epididymal cells and is absorbed to the surface of sperm during transit through the epididymis.
Protein: BIOD_BURMS
Sequence: MSAPLSLFVTGTDTEIGKTFVSAALLHGFARAGLRAAAMKPVAAGAYERDGAWRNEDADQLDAAANVALPAAIRTPFLLKAPAAPHIVAAREGVALDIGTIVDAHRRACEMADVIVVEGVGGVRVPLADTRDTADLAVALGLPVVLVVGVRLGCISHALLTAEAIAARGLPLAGWVANRIDPAMPFADDNIDTLRAWLEREHRAPLLGALAHMSPPSPDAASHALDVNLLLNALRAAAPR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPA_ECO45
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGTKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CREC_ASPNC
Sequence: MFVLPPPPPRYTVPVAYAAGASNGMAVPVVETNNIISHPEGGCSLQAGEGTYLLRDDLHLATPPPHPSEAPVMNPNPLATVPAPPTSGVKLSLVSIGSRIKTPTPSVDGVGAASLFGDGNPALAAPPVKEGLKRRKPKNNIIKSSSSFVSRVITHETATKRLNDRNPDGLFAFANINRAFQWLDLSAKQKEEPVTKILFTKAHMISHDINELTKSTSHIDVVMGSSAGDIIWYEPMSQKYARINKNGVVNNSPVTHIKWIPGSENLFMAAHANGQLVVYDKEKEDALFAPELGSPSAETMKSSSGRSPLQILKSVNSRNQKTNPVALWKLANQKITQFAFSPDRRHLAVVLEDGSLRVMDYLKEEVLDIFRSYYGGLICVCWSPDGKYIVTGGQDDLVTIWSLPERKIVARCQGHNSWVSAVAFDPWRCDDRTYRFGSVGDDCRLLLWDFSVGMLHRPRVHQANARQRTSMIVSNTQHLNRHRADSGGNRTRSDSQETADTYNSYDPTVRHPVEPRARTALLPPIMSKIVGEDPICWLGFQEDSIMTSSLEGHIRTWDRPREGINDNYSYSPAISASATGSGRADSMMGSL
What is the function of this protein?
Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression.  CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways (By similarity).
What are the official names of this protein?
Probable catabolite repression protein creC.
What is the protein family that this protein belongs to?
Belongs to the WD repeat creC family.
Protein: NUSG_STAES
Sequence: MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKKLVKKTFPGYVLVELIMTDESWYVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGLKEKTIDVELDVGEQVRIQSGPFANQIGEVQEIEADKFKLTVLVDMFGRETPVEVEFDQIEKL
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: RL18_BORAP
Sequence: MKKIKEAEQRKIRRKKRIKDKIGRGIATRPRITIFKSNRYFYAQVIDDSKGHTVASISTIEKSLNLSKNIDDIKKLGEVLAKRLKEKNINNLIFDRNGYKYHGLIASFATSLREFGINI
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GLGC_ECOLI
Sequence: MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: YR704_MIMIV
Sequence: MLNSSTNNTSSPIINSIETTDIEEKYRKYYVPNDLYWGIGIENESYFMLDKTIERTGEYIKKNRRRERYSVDYNTSYDQEKLTNYLNKLFGDRDLFNIPQYVNSHTLSKTDTQGEHRTLYVIGQKNNPKYSGKSLHELFLETNNLYQLDFNHKYVFDGDTIEFITQNFYKTTVNDCVNELIMYKNKFVNDMNILMKKNNLPLLSFPKINFGLVHFRTNPNNIGIFNNGTYHINLTMPTKLNSQGEIADPILFEKRHKNAIELIKWIEPLIIALYGSPDVFSVEDNQKYSKGSLRLTASRYVSIGTYDTNIMKKGKQLNDLKDSMYLYLYDKSWYNKIYQQTDYKQCDHIGYDINYAKHLNLGIEFRILDYFPEEVLGELIKFIVLILDHSFETKIDLQSVECKEWHDFVCDALINGNTVIVPKELGLIMNQFIGFPLIKHNMSIKKYMKKLSKFLHKKYANSLCSRNMSPNMQVPKIYNINKYMWENNFLQYIPINNKNHLKVLKLYHIYSDLKSDKITFDPENNYHSILVNSDLLQESELDLDTFYEKLLKISNSKIPINKYIL
What are the official names of this protein?
Uncharacterized protein R704.
Protein: FB48_ARATH
Sequence: MKPQEEEEKNENMARKRSKSSSSLSIPLDIATDIFLRLPAKSVVRFSCVAKHWSSITTAPYFTNSFETRPNLLFFFKEADRFFVVTVPKPNRRPNESVSHTSSQILDSYQTPYPKHSCFTIKTESVHGLICFQRGTKPIVWNPTMRKFKPLRKPDKSWESLTVFLGYDPLERTHKVVAMPCDKASDECRILTLGSADQESWRTVKTNYKHHPSRGNRKNNYGPCRCINGVLYYLAEIDRHRLIGKFAFLGHSNVKNSLPMWVLEGEKKGEWSTYNFLPLSHYDRRLEFHFKLIGITNDGELIYVPNTVFKTFEVIYIDPIRKTFSLVKYEGVADKGFRQRNGLGEDKPLRGIQYSPNHVETLLSL
What are the official names of this protein?
F-box protein At1g48060.
Protein: CCME_DEIRA
Sequence: MTTAPSGLPGTPLPPARRRERPRWPLLVAGAAVLGLIGYMVLGNANSNLVYYVLPSEYQQDTAKFAGKTLRMGGLAKDVVYNRDTLALKFNMTDGQVAYPVQYQGAVPDMFRNDAVVVMEGQMQQGVFHGKSLLVKHSEEYKAADSKGEGQYSQDDLKKILNDQSTKP
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: HXB7B_XENLA
Sequence: MSSLYYANALFSKYPTATSVFPSGVFSEQTSCAFASSPQRSGYGNSPGGTFPAGSAAHGLFSNGSSLHPQSPAMYPSSYGLDAASFNMHCSPFEQNLSSLMCDPTKQNCTKAEQRDSELHNEANLRIYPWMRSAGSDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKASSPSSNSQEKPETEEEEEEEE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B7-B, P52, XlHbox-2 B.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RDRP_TOMK2
Sequence: MAYTQTATSSALLETVRGNNTLVNDLAKRRLYDTAVDEFNARDRRPKVNFSKVVSEEQTLIATKAYPEFQITFYNTQNAVHSLAGGLRSLELEYLMMQIPYGSLTYDIGGNFASHLFKGRAYVHCCMPNLDVRDIMRHEGQKDSIELYLSRLERGNKHVPNFQKEAFERYAEMPNEVVCHDTFQTCRHSQECYTGRVYAIALHSIYDIPADEFGAALLRKNVHVCYAAFHFSENLLLEDSHVNLDEINACFQRDGDRLTFSFASESTLNHSHSYSNILKYVCKTYFPASNREVYMKEFLVTRVNTWFCKFSRIDTFLFYKGVAHKGVDSEQFYKAMEDAWHYKKTLAMCNSERILLEDSSSVNYWFPKMRDMVIVPLFDISLETSKRTRKEVLVSKDFVYTVLNHIRTYQAKALTYSNVLSFVESIRSRVIINGVTARSEWDVDKSLLQSLSMTFFLHTKLAVLKDDLLISKFALGPKTVSQHVWDEISLAFGNAFPSIKERLINRKLIKITENALEIRVPDLYVTFHDRLVSEYKMSVDMPVLDIRKKMEETEEMYNALSELSVLKNSDKFDVDVFSQMCQSLEVDPMTAAKVIVAVMSNESGLTLTFEQPTEANVALALQDSEKASDGALVVTSRDVEEPSIRGSMARGELQLAGLSGDVPESSYTRSEEIESLEQFHMATASSLIHKQMCSIVYTGPLKVQQMKNFIDSLVASLSAAVSNLVKILKDTAAIDLETRQKFGVLDVASKRWLVKPSAKNHAWGVVETHARKYHVALLEHDEFGIITCDNWRRVAVSSESVVYSDMAKLRTLRRLLKDGEPHVSSAKVVLVDGVPGCGKTKEILSRVNFEEDLILVPGRQAAEMIRRRANASGIIVATKDNVRTVDSFLMNYGKGARCQFKRLFIDEGLMLHTGCVNFLVEMSLCDIAYVYGDTQQIPYINRVTGFPYPAHFAKLEVDEVETRRTTLRCPADVTHFLNQRYEGHVMCTSSEKKSVSQEMVSGAASINPVSKPLKGKILTFTQSDKEALLSRGYADVHTVHEVQGETYADVSLVRLTPTPVSIIARDSPHVLVSLSRHTKSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDAGTQXQLQVDSVFKNFNLFVAAPKTGDISDMQFYYDKCLPGNSTLLNNYDAVTMKLTDISLNVKDCILDMSKSVAAPKDVKPTLIPMVRTAAEMPRQTGLLENLVAMIKRNFNSPELSGVVDIENTASLVVDKFFDSYLLKEKRKPNKNFSLFSRESLNRWIAKQEQVTIGQLADFDFVDLPAVDQYRHMIKAQPKQKLDLSIQTEYPALQTIVYHSKKINAIFGPLFSELTRQLLDSIDSSRFLFFTRKTPAQIEDFFGDLDSHVPMDVLELDVSKYDKSQNEFHCAVEYEIWRRLGLEDFLAEVWKQGHRKTTLKDYTAGIKTCLWYQRKSGDVTTFIGNTVIIASCLASMLPMEKLIKGAFCGDDSLLYFPKGCEYPDIQQAANLMWNFEAKLFKKQYGYFCGRYVIHHDRGCIVYYDPLKLISKLGAKHIKDWDHLEEFRRSLCDVAESLNNCAYYTQLDDAVGEVHKTAPPGSFVYKSLVKYLSDKVLFRSLFLDGSSC
What is the function of this protein?
Is a methyltransferase active in RNA capping and an RNA helicase.  Methyltransferase displays a cytoplasmic capping enzyme activity.  This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus.  Helicase region probably exhibits NTPase and RNA unwinding activities (Potential).  It also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  May mediate silencing suppression through either inhibition of HEN1-mediated siRNA or siRNA demethylation (By similarity).
What are the official names of this protein?
Replicase large subunit, 183 kDa protein, RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: TEAN2_MOUSE
Sequence: MDKFVIRTPRIQNSPKKKLGEKVYKQATIESLKRVVVIEDIKRWKTMLELPDQTKENLVAALQELKKKMPSREVLRSTRIGHAVNKMRRHSDPEVAGLAKEVYTEWKTFIEKHLDRPSIEVRSDPKTESFRKNAQKLLSEALELKMDHLLVENIERETFHLCSRLINGPYRRTVRALVFTLKHRAEIREQVKSGALPVGTFVQTHKK
What are the official names of this protein?
Transcription elongation factor A N-terminal and central domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TCEANC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AT1B3_BOVIN
Sequence: MTKTDKKSFNQSLAEWKLFIYNRTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWAMLQTLNDEVPKYRDQIPSPGLMVFPKPVSALDFSFSLSDAESYQGYIDDLKKFLKPYGLEEQKNLTDCTNGTFFEQKGPEYTACQFPLALLEACSGVDDPTFGYQEGKPCILVKMNRIIGLKPQGEPRIECTGKSESTAFLSTYPSNGTIDLKYFPYYGKKLHGNYLQPLVAVQVGFGSDADVREVMVECKIDGSPNLKTQNDRDKFLGRVAFKITMHA
What is the function of this protein?
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.  The exact function of the beta-3 subunit is not known (By similarity).
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-3, Sodium/potassium-dependent ATPase subunit beta-3, ATPB-3.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: CCS1_SCHPO
Sequence: MFEVEYLIKDCDDVNKNTLEQEFQDLNIEDWKWDAATGQLIVKGSVSPSKVLRRLENATSKPILIRGASNKESGVSILYEANEDITQIPKVYGLCRFIPTEEKIFLDLIATQLLPNREYTGLVTISGDISRGLKSAGDSLVTLFNANSNEQGKIVLDKEVSGSLPNWIGHCFVLKCVDDSDSATMGIISRSAGLGQNTKQICACTGKSLWTEHAELKSVNEGSSCCSKKDSSPSEKPSCCSQEKKSCCSSKKPSCCSQEKKGCCSTEKTSCCSQEKKSCCTSEKPSCCSNGKSTVCA
What is the function of this protein?
Copper chaperone for superoxide dismutase 1 (sod1).  Binds copper ions and delivers them specifically to sod1.  Also has a role in cell protection against copper ion toxicity during conditions of copper excess.  The C-terminal region is thought to act specifically in this sequestration role.
What are the official names of this protein?
Superoxide dismutase 1 copper chaperone.
What is the protein family that this protein belongs to?
Belongs to the CCS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_CAMJE
Sequence: MQENLKNDKLKIGKYEFDSRFILGSGKYSLELIKSAIEEAKAQIITLALRRANTGEIANILDYIPKNITLLPNTSGARNADEALRIARLSRELGCGELIKIEVISDSRYLLPDNYETIKACELLAKEGFTPLPYMHADLYAARAMRDAGAAAIMPLAAPIGSNKGLCAKEFIQILLNEIDLPIIVDAGIGSPSQACEAMQMGVSAVMVNTAIAEAKDIALMARAFSLAVNAGRVAFLAGVASVSEAKASSPLTGFLRD
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4385_TRIEI
Sequence: MKIRNYIIIAISVILLVVFSLSRTLVHLLTEAWWFNTVDFANIFWTRLNWQIFLWVGAFVIYFLFLWSNYWIAEKLTSDRSFNILLGTELAPYRNIFVKIIFLVNITLISLSAATATSPAWETFLKFLNAVDFPNQDPIYQRNIGFYIFRLPLYEGIKEWLFTLVFAGLIISIIVYALKGKFTAGRQWQNFLTGSIKTHISLLLAGVTILIAVGFWFERYELLFDSNGVVFGAGYTDVHAKLFAYWAMAIVALLLAVVCVLSVWKNNIIWPTYGIVIYIVLLGLFNVLYPWFQQKFIVNPNELQKEKPYIANNIKFTREAYGLDNVETKSFPAKFELDSQTLKNNQGTVRNITLWDYRPLLSTYRQLQEMRLYYQFNDVDIDRYTIDGNYRQVMLSPREMVYSQVPRKAQTWVNKHLKYTHGYGLVMNPVNEVKADGLPVLFIKDIPPVSQVNLQVKEPAIYYGEKTDTHIFTGMSTEEFDYPRSGENAFTFYSGTGGVPVNSLWRKLAYAYDLSSINILISGYFTDNSKIHYYRNIKERVNQVAPFLRFDNDPYIALIDGKIQWILDAYTVSDRYPYSEPLYLSNNARAILNRGNIERIARGNVNYIRNSVKVMVDAYNGTMKFFVVDENDPVLNTYRKIFPQLFTEKSAIPTNVKAHFRYPLDLFKIKAQMYLSYHMSNPQLFYNQEDLWRFPTEVYEDNKQLMEPYYLIMRLPEKKGEEFVLILPFTPVNKDNMIAWMAAESDGDNYGKLLLYEFPKQKLVYGPSQIEARIDQNPKISQQLTLWSQKGSKVIRGDLLVIPIEESLMYIEPIYLRAEQGELPELKRVIVAYDKEVVMTETLSKSLETIFGMEVKQPEVKVTEKTPETKNISELINSIVEAYSQTEAARRKDNWVEYGKSKQKFEQLLQQLKKQTESN
What are the official names of this protein?
UPF0182 protein Tery_4385.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_ECO8A
Sequence: MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQILADEVGAEVIALSEIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMAWLRAQSASETIREYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAPTKSLQQAARDGDNERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CYB_MICOE
Sequence: MTIIRKKHPLIKMINHSFIDLPAPSNISSWWNFGSLLGLCLMIQIITGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGVYYGSYNMIETWNMGIVLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDTDKIPFHPYYTIKDFLGVLILLMVLMILALFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPLLHTSKQRALTFRPITQTMYWILVADLLVLTWIGGQPVEYPFIIIGQTASIAYFAIIVILMPIAGMIENNILNLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.