PharMolix/UniProtQA huggingface dataset:
Protein: T2TA_HELPY
Sequence: MFGLGLADVILERFKDFMREQPEPYKFLQVFYAQEKERFLNHKMSDYIKQNKSKEEASILARQGFVSAVGRALEKIIELLLKDFCIKNNVKMTNDKILRAKRINGELDRVKRALWVHFGEYSVLPDIILYQTNKDNIKILAILSVKNSFRERFTETPYWKLKLLQSPVTSHIKVFMITPDNDDEISFKDKPKG
What is the function of this protein?
A P subtype probable restriction enzyme that recognizes the double-stranded sequence CCGG; the cleavage site is unknown.
What are the official names of this protein?
Probable type II restriction enzyme HpyAORF263P, HpyAORF263P, Endonuclease HpyAORF263P, Type-2 restriction enzyme HpyAORF263P.
What is the protein family that this protein belongs to?
Belongs to the BsaWI type II restriction endonuclease family.
Protein: DNAA_SHESM
Sequence: MAVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVRDKYINIINQFFTEQMGNDAPKLRFDIGSRPSAKKPEPAPVAAVRVPNPQTKASVGTSFNTTEPVANTNHRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQVAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TET4_ARATH
Sequence: MRSRSNLIGLINFFTFLLSIPILGGGIWLSSRANSTDCLRFLQWPLIIIGISIMVISLAGIAGACYQNKFLMWLYLFTMFFVIAALIGFTIFAYVVTDKGSGRFVMNRRYLDYYLNDYSGWLKDRVTDNGYWRDIGSCVRDSGVCKKIGRDLNGVPETAHMFYFRNLSPVESGCCKPPTDCGYTYVNETVWIPGGEMVGPNPDCMLWNNDQRLLCYQCSSCKAGVLGSLKKSWRKVSVINIVVVIILVIFYVIACAAYQNVKRMYNDEPVGEARMTNLILVIFKFKEILVQFFFGIVFLLLFNGLMVCCCNDKFAFSVFFFGYVTYA
What is the function of this protein?
May be involved in the regulation of cell differentiation.
What are the official names of this protein?
Tetraspanin-4.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BIOD_CLOBJ
Sequence: MARGIFITATGTDIGKTYVTALIIKRLRETNINCGYYKAALSEAERRDGKLIAGDANYVYNIANIKGDPNDAVSYIFQQAVSPHLAAKLNNVEISMERIKKDFYSIKNKYDYITVEGSGGIVCPISTGKEKIMLDNIIKIFKLPAIVVADAGLGTINSTILTLQYMKEKNISVKMILLNNYNHEDIIHIENKGYLSDNLLIPVYTCNKNANNLEIPVEKLIEIYEEI
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_YERPA
Sequence: MPKIKTVRGAAKRFKKTANGGFKRKHANLRHILTKKATKRKRHLRPKGLVSKNDLGLVVACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PSA4_RAT
Sequence: MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAVKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQREKDK
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit alpha type-4, Macropain subunit C9, Multicatalytic endopeptidase complex subunit C9, Proteasome component C9, Proteasome subunit L.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9 (By similarity). Colocalizes with TRIM5 in the cytoplasmic bodies (By similarity).
Protein: GLYA_YERPG
Sequence: MLKREMNIADYDADLWRAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKALFGADYANVQPHSGSQANVAVYSALLKPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDESGQIDYEDLARQAEIHKPKMIIGGFSAYSGIVDWAKMREIADSIDAWFFVDMAHVAGLVAAGVYPNPVPHAHIVTTTTHKTLAGPRGGLILAKGGDEDLYKKLNSSVFPGNQGGPLMHVIAGKAVALKEAMEPEFKIYQQQVAKNAKAMVAVFLERGYKVVSGGTDNHLFLLDLVDKDITGKDADAALGRANITVNKNSVPNDPKSPFVTSGVRIGSPAITRRGFKEAESRELAGWMCDVLDNINDEATIERVKQKVLAICARLPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_ANAD2
Sequence: MSTGLLAKKVGMTQIFTPEGDCVPVTVLEAGPCTVVRRKTAEKDGYDAVVIGFGVVDEKHAHRLSKPEVGVFKKAGTPIFRHVKEIRVKDAKQLGDLKAGDVLTVDKVFKANQRIDVAGVTKGRGFTGVMKRWNMKGAARDSSTAHEHHRHVGAIGQRKTPGKVWKGKHLPGHYGVDNVTIQNLTVVGIEAEQNVLLVSGAVPGHADGLLFVNTAAKGQPRIKQKQEVRERAKPKV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CYB_SCOSC
Sequence: MASLRKTHPLLKIANDALVDLPSPANISVWWNFGSLLGLCLASQILTGLFLAMHYTPDVESAFNSVAHICRDVNFGWLIRNMHANGASFFFICLYLHIGRGLYYGSYLFVETWNVGVVLLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGTTLVEWIWGGFSVDNATLTRFFAFHFLFPFVILAAAVLHLLFLHETGSNNPIGLNSNADKISFHPYFTYKDLLGFAVLLMGLTSLALFSPNLLGDPDNFTPANPMVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILMVVPFLHTSKQRALTFRPASQFLFWTLVADVVVLTWIGGMPAEQPFIIIGQVASVLYFSLFLVLFPLAGWAENKVLGWT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RR7_SOLNI
Sequence: MSRRGTAEKKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDITVKARRVGGSTHQVPIEIGSTQGKALAIRWLLAASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: G6PI_SHESM
Sequence: MTILTQSTTWQALAAHSHQIPHMRELFAGDPARFSNMSLSTCGLFLDYSKNRATPETLNLLQTLAQEAKLDAKIKAMFAGDIINTTEKRAVLHTALRSTAEQSIVAEGQDIVPEVQQTLNKMQQFVTSVTSGQWKGFTGKAITDIVSIGIGGSFLGPKIVSQALRPYWITGLNCHFVANVDGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAKAWFLAKGGSQSDVAKHFVAVTSNVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRSLLKGAHQMDTHFANAPLAENMPVIMGLFSLWYGNFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGTHVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFIMPLQSHNPIGEHHDQLASNCFGQTQALMQGRTLDEALAELSKSSLSDEEKLLIAKHKVMPGNKPSNTLLMDKLTPETLGALIALYEHRTFVQGAIWDINSFDQWGVELGKSLGNDVLARIGAEQDATALDASSNGLINLYRQGKI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_XANAC
Sequence: MNTSITARELFDQQRDKLALRWVAGPKGEHREIQANSNNARRPSLAGYLNVIYPNKVQILGTEELAWLDSLDARQRWETIEKIIQVQPLALAISKNQSCPEDLRAAADESNTPLWISSKRGHELLNHLSYHLARTLAPRVTLHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVADDAPEFTQIAPDVLDGTCPELLQDLLEVRGLGVLNVRDMFGDTAVKKNKYLRLIVHLTRPMTEPTPSGYERLTGDSGSRHVLDLDVPLITLPVMPGRNLAVLTEAATRLHILRTKGIDPAAMFIARHSNLLERRTP
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: RPPH_NITEC
Sequence: MIDRNGYRANVGIILLNSKSQVFWGKRARQNSWQFPQGGIKSGETPTQAMYRELAEETGLQPVHVEILGRTREWLRYDVPACWTRRDWRKNYRGQKQIWFLLRMLGRDCDVSLKTCAHPEFDAWRWNQYWVELESVVEFKRQVYRLALTELSRLLDHETCLGNDQAYREPLEPVKELEEKSSDARQG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: LGSN_MOUSE
Sequence: MTDEGDLAQEDTAKDEGNVTEGSRMSKLRRARRKVTKPHLCSMDGEEIAKANSSEMSRNQIADLSKPGSAESWSSHSAKDAYHPTPVVKPSLPSALAGAPDAEFSPNTDPTRYNAQSFNPPQLSARMKHIKQEMAKNHLQFVRFEATDLHGVSRSKSIPAQFFQEKVIHGVFMPRGYLELMPNPKDNEVNHIRATCFNSDIVLMPELSTFRVLPWAERTARVICDTFTVTGEPLLTSPRYIAKRQLRQLQDAGFCLLSAFIYDFCIFGVPEVINSKTISFPASTLLSNHDQPFMQELVEGLYQTGANVESFSSSTRPGQMEICFLPEFGISSADNAFTLRTGLQEVARRYNYIASLVIETGFCNSGILSHSIWDVGGKTNMFCSGSGVERLTLTGKKWLAGLLKHSAALSCLMAPAVNCRKRYCKDSRDLKDSVPTTWGYNDNSCALNIKCHGEKGTQIENKLGSATANPYLVLAATVAAGLDGLQSSDGAAAGSDESQDLYQPEPSEIPLKMEDALAALEQDECLKQALGETFIRYFVAMKKYELENEETDAEGNKFLEYFI
What is the function of this protein?
May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens.  Does not seem to have enzymatic activity.
What are the official names of this protein?
Lengsin, Glutamate-ammonia ligase domain-containing protein 1, Lens glutamine synthase-like.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
Protein: TWST1_SAGOE
Sequence: MMQDVSSSPVSPADDSLSNSEEEPDRQQPQSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGSAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH
What is the function of this protein?
Acts as a transcriptional regulator.  Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction.  This interaction probably involves the basic domains of both proteins.  Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B.  Regulates cranial suture patterning and fusion.  Activates transcription as a heterodimer with E proteins.  Regulates gene expression differentially, depending on dimer composition.  Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression.  Heterodimerization is also required for osteoblast differentiation.  Represses the activity of the circadian transcriptional activator: NPAS2-BMAL1 heterodimer (By similarity).
What are the official names of this protein?
Twist-related protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ILVC_METMP
Sequence: MKVFYDSDFKLDALKEKTIAVIGYGSQGRAQSLNMKDSGLNVVVGLRKNGASWNNAKADGHNVMTIEEAAEKADIIHILIPDELQAEVYESQIKPYLKEGKTLSFSHGFNIHYGFIVPPKGVNVVLVAPKSPGKMVRRTYEEGFGVPGLICIEIDATNNAFDIVSAMAKGIGLSRAGVIQTTFKEETETDLFGEQAVLCGGVTELIKAGFETLVEAGYAPEMAYFETCHELKLIVDLIYQKGFKNMWNDVSNTAEYGGLTRRSRIVTADSKAAMKEILREIQDGRFTKEFLLEKQVSYAHLKSMRRLEGDLQIEEVGAKLRKMCGLEKEE
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MTAD_DESHD
Sequence: MSKILIRAMVLPMTGPEDFYPEGEIGIENDRILFVGEKGSAPDSFIPDQIIDLPEDVVMPGLINTHTHAAMTMLRSYADDLPLMPWLQTKIWPFEDKMSDEDIYWGTLLALGEMIQSGTTTMLDMYASMDQVAKAVLEAGTRGVLSRGLIGNAPNGERAFAENMDLVKNYHGAGQGRIQVMFGPHAPYTCSGEFLQRVKQEADRLGVGIHIHVAETEDEIKTIKEQYGKTPVQWLEELGLFGGHVVAAHCVHLTEEDQEIMAQNKVFIAHNPESNMKLNSGTAPIPELRSRGVVVGLGTDGTSSNNNLDMFGEMRSAAFQQKLVKGATALPAYEVLQMATVDGARTLGLHDVGVLAPGYKADLISINFDQPHFYPRFSIPAHLVYVAHAGDVRTVMVDGKILMQERQLMTIDIKRVCREVEKRAKGIAQGL
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: LPP3_ARATH
Sequence: MARFSFPCFPNFGGFNQAVTNRGPEISETADNWVSPSDIPLIEPNSKEHRMREAQLGGHTLRSHGMTVARTHMHDWIILVLLVILECVLLIIHPFYRFVGKDMMTDLSYPLKSNTVPIWSVPVYAMLLPLVIFIFIYFRRRDVYDLHHAVLGLLYSVLVTAVLTDAIKNAVGRPRPDFFWRCFPDGKALYDSLGDVICHGDKSVIREGHKSFPSGHTSWSFSGLGFLSLYLSGKIQAFDGKGHVAKLCIVILPLLFAALVGISRVDDYWHHWQDVFAGGLLGLAISTICYLQFFPPPYHTEGWGPYAYFQVLEAARVQGAANGAVQQPPPQVNNGEEEDGGFMGLHLVDNPTMRREEDVETGRG
What are the official names of this protein?
Putative lipid phosphate phosphatase 3, chloroplastic, AtLPP3, Phosphatidate phosphohydrolase 3, Phosphatidic acid phosphatase 3.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: F216B_HUMAN
Sequence: MGQNWKRQQKLWNVPQLPFIRVPPSIYDTSLLKALNQGQQRYFYSIMRIYNSRPQWEALQTRYIHSLQHQQLLGYITQREALSYALVLRDSTKRASAKVAPQRTIPRKTSAMTRRCPSVLPVSVVLPRAQSKRRQVLRN
What are the official names of this protein?
Protein FAM216B.
What is the protein family that this protein belongs to?
Belongs to the FAM216 family.
Protein: IF3_AZOVI
Sequence: MKREMRQDRKAQPKAPINENISAREVRLIGVDGEQIGIVSIDEALRVAEEAKLDLVEISADAVPPVCRIMDYGKHLFEKKKQVAAAKKNQKQVQIKEIKFRPGTEEGDYQVKLRNLVRFLNDGDKAKVSLRFRGREMAHQELGMELLKRVENDLAEFGTVEQYPKLEGRQLMMVIAPKKRK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INV_DEBHA
Sequence: MKITTLVASILMSVLLEPVIASFIDTGKDTSAYNRPLIHLTPNVGWLNDPNGLFYDKKTSVWHAYYQYNPNDTIWGQPLYWGHSSSKDLTHWEEHQVALGPQNDDEGIFSGSIVIDYNNTSGFFDESIDKDQRVVAIYTNSIPDTQTQDIAYSLDGGETFTKYKKNPVIDVNSTQFRDPKVFWHEETNKWIMVVSKSQEYKIQIFGSLDLKTWDLHSNFTSGYLGNQYECPGLIKVPIENTNDYKWVMFLAINPGSPAGGSSNQYFIGEFDGFEFKQDDSITRVMDAGKDFYAFQTFSDNEQDVIGLAWASNWQYANVVPTNPWRSSMSLARKYTLGYVNQNVETKIMTLIQTPILNNLDVINKVEKNNHLLTKNDSVITNFSSSTGLLDFNTTFKVVGESIDSNSLSNIEILIHSQMSNSSTESIKVGFDRSVSAFYFNRDIPNVEFNNNPYFTNKFSTYVEPSHYDEDDMPVYKIYGIVDKNILELYFNDGTQTMTNTFFMSEDKYPHQIEIASNVDGQFELQSLLIRELNN
What are the official names of this protein?
Invertase, Beta-fructofuranosidase, Saccharase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: CLCA_YERPA
Sequence: MTHSTQQLSPEGVAEGKRGRLIRELVNRDKTPLIILIMAAVVGVVTGLLGVAFDRGVDWVQQQRLLALANVADYALLVWPLAFIMSALLAMMGYFLVSRFAPEAGGSGIPEIEGAMEEMRPVRWWRVIPVKFIGGLGTLGAGMVLGREGPMVQMGGNSGRMIVDIFRLRSPEARHSLLATGAAAGLSAAFNAPLAGILFVIEEMRSQFRYSLVSIKAVFIGVITSTIVYRYFNGERAIIEVGKLSDAPLNTLWLYLLLGIIFGAVGVIFNALIFRTQDMFVRFHGGDWRKLVLIGGLLGGMCGLLALLHGNAVGGGFALIPIAAAGNFSIGMLLFIFIARVITTLLCFGSGAPGGIFAPMLALGTILGTAFGLSCAHFFPQYGIEAGTFAIAGMGALFAASVRAPLTGIVLVLEMTDNYQLILPMIVTCLGATLIAQFMGGKPLYSAILARTLAKQEQARATVIAQEPAVENTPQIGK
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOZ_ACICJ
Sequence: MARVTVEDCIEQIPNRFELVLLAAQRARNLSRGASITIDRDNDKNPVVALREIADSTVDFGGLEQDLVKSLSRVPDPEPADEEVQDLIPTDQNIFGLQDVSAEEEAAAMAAESEEMTSEDIAAAIEAELGGGRPRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: Y3976_AGRRK
Sequence: MLKWAIIFFVISLIAGFFGFSGVSAATATIARVLFAIFLIVFLVFLILAVMAGNAVL
What are the official names of this protein?
UPF0391 membrane protein Arad_3976.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIBL_METMP
Sequence: MEKKIAVTAGTFDLLHPGHFNTLNFAKKHADELVVIIARDETVKKIKGRSPVIPEEQRKIMIEALKPVDRAVLGSLTNKLEPILEIRPDVIVLGPDQTTYQINELKAQLAEHSLYPEILKVEDYVKCPFHSSYDILKEIVRRWCCKELKV
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: YA99_SCHPO
Sequence: MEDVDLGFLSQEKLDEKDYLDIECSRVGGAPLFIRKNDAAFLNESLENSFEFLMQLYAPKNSEISYHRILYIFINRDGDSQTAGWTRGVKVFREQARETDEIDFQLITSKVTKLIDSSEIEVDAEPKEENKKEIPEKLKNVKVDTENPSAEPYTKAKGDVSFLKFQKRLSRAPDQIMRYYHATSNEFPGLWCNNECIPSSIPNCACGAKRQLEFQILPTLISSMNIDHSAKNALDWGILSIYVCSASCDLANCGLAEELCWLQTFSEQGIIAPE
What are the official names of this protein?
Uncharacterized protein C13G6.09.
What is the protein family that this protein belongs to?
To mammalian protein PDCD2.
Protein: SRP54_PYRHO
Sequence: MVLDSLGRALSNALKKIARAGSVDEALVKEVVRDIQRALLQADVNVRLVLKLTKEIQRRALEEKPPAGISKKEHIIKIVYEELTKFLGTEAKPIEIKEKPTVLLTVGVQGSGKTTTVAKLARYFQKRGYKVGVVCSDTWRPGAYHQLKQLLDPYHIEVFGDPNEKDAVKLAKEGVEYFKTRDVDLIIVDTAGRHKEEKDLIEEMRMISEEIRPHEVILVIDGTIGQQAYNQALAFKEATPIGSIIVTKLDSSAKGGGALSAVAATGAPIKFIGVGEKIDDLEPFDPARFVSRLLGLGDIQGLLEKFKELEKEVEFTEEDIDRFLRGKFTLKDMYAQLEAMRKMGPLKQILRMIPGLGYSLPDELISVGEERLRKFKVIMDSMTEEELMNPEIINYSRIKRIARGSGTSIKDVKELLTQYNQMKKFFKSMNKRQLSRLARRFGM
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: HEM3_KLEP7
Sequence: MLDKVLKIATRQSPLALWQAQYVKARLEQAHPGLKVELVPMVTRGDVILDTPLAKVGGKGLFVKELELAMLEGRADIAVHSMKDVPVEFPEGLGLVTICERDDPRDAFVSNRYASIDELPAGSVVGTSSLRRQCQLAATRPDLAIRSLRGNVGTRLSKLDNGEYDAIILAAAGLKRLQLEARIRQPLSPEQSLPAVGQGAVGIECRLDDAWTRGLLAPLNHTETAVRVRAERAMNTRLEGGCQVPIGSYAELKDGELWLRALVGAPDGSQLVRGERRGPAEQAEALGISLAEELLDNGAREILAAVYDGEAPR
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RL44_KLUMA
Sequence: MVNVPKTRKTYCKGKACRKHSQHKVTQYKAGKASLYAQGKRRYDRKQSGFGGQTKQIFHKKAKTTKKVVLRLECMSCKTKTQLALKRCKHFELGGEKKQKGQALQF
What are the official names of this protein?
60S ribosomal protein L44, 60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.