PharMolix/UniProtQA huggingface dataset:
Protein: MTBB3_METMA
Sequence: MATEYALRMGDGKRIFLTKDKIIEELEAGMANASDLGEIPDLSGDEIDKLAEILMMPGKAVSVEQGMEVPVTHDIGTLRLDGDQGNSGVGIPSSRLVGCMMHERAFGADTMELGHIDYSYKPVKPVVANECQAMEVCQQNMIIPLFYGAMPNMGLYYTPDGPFENPGDLMKAFKIQEAWDSMEHAAAHLTRDTVWVMQKLFASGADGVNFDTTAAAGDADMYGTLHAIEALRKEFPDMYIEAGMAGECVLGMHGNLQYDGVTLAGLWPHQQAPLIAKAGANVFGPVCNTNTSKTSPWNLARAVNFMKAAVQASSIPCHVDMGMGVGGIPMLETPPIDAVTRASKAMVEIAGVDGIOIGVGDPLGMPISHIMASGMTGMRAAGDLVARMQFSKNMKIKEAKEYVAKKLNVETMDLADEYVMRELREELDIGVITSVPGAAKGIAAKMNIEKLLDVKINSCNLFRKQTR
What is the function of this protein?
Catalyzes the transfer of a methyl group from dimethylamine to the corrinoid cofactor of MtbC.
What are the official names of this protein?
Dimethylamine methyltransferase MtbB3, DMA methyltransferase 3, DMAMT 3, Dimethylamine--corrinoid protein methyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the dimethylamine methyltransferase family.
Protein: GPDA_SHEWM
Sequence: MKNTADITVLGAGSYGTALAISLASNGHRTLLWGHDPEHIENLKRDRANEAFLPGITLPDLLVPEADLATALAASNNVLVVVPSHVFGLVLEQAKPLLREDSRIVWATKGLEPETGRLLQEVAREVLGDKYPLAVLSGPTFAKELAAGMPTAISVAGTDESFTQDLVELLHSSNRLRVYANDDFTGLQLGGAVKNVIAISAGMSDGIGFGANARTALITRGLVELTRLGEAIGAQASTFMGMAGLGDLVLTCTDNQSRNRRFGLALGKGQGVEEAQVEIGQVVEGYRNTKEVYTLAKRLGVEMPITEQVYKVLYQGGTPHEAAKSLLAREKKSETEDSE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSET_DANRE
Sequence: MMNFRQRMGWIGVGLYLLASVAAVYYIFEISQTYNRLALAQVEKTSGAQAKWPGDASSSSPSSTSWIVTLKTRLLLLPFWVWATIFLLPYLQVFLFLYSCTRADPKTVGYCILPICLAVLCNRHQTFTKASNQISRLQLIDT
What is the function of this protein?
Required for mannose-6-phosphate-dependent trafficking of lysosomal enzymes (PubMed:36096887).  LYSET bridges GlcNAc-1-phosphate transferase (GNPTAB), to the membrane-bound transcription factor site-1 protease (MBTPS1), thus allowing proteolytic activation of the GNPTAB.  GNPTAB is involved in the regulation of M6P-dependent Golgi-to-lysosome trafficking of lysosomal enzymes.  LYSET is thus an essential factor for maturation and delivery of lysosomal hydrolases (By similarity).
What are the official names of this protein?
Lysosomal enzyme trafficking factor, Transmembrane protein 251.
What is the protein family that this protein belongs to?
Belongs to the LYSET family.
Protein: URE1_MARMS
Sequence: MATMDRQSYAQMFGPTTGDRVRLGDTDIWIQVEKDFTVYGDEVKFGGGKVIRDGMGQSQVTNEIAVDLVITNALVLDHWGIVKGDVGIKDGRIFKVGKAGNPDVQDNVDIVVGPGTEVIAGEGSILTAGGIDAHIHFICPQQVEEALTSGVTTMIGGGTGPATGTKATTCTSGPWYLGKMLQATDSMPMNLGFLGKGNASLPEALEEQLEAGACGLKLHEDWGTTPASIDCCLSVAEAYDVQVAIHTDTLNESGFVDSTIDAFKDRVIHTYHTEGAGGGHAPDIIQACSNPNVLPSSTNPTRPYTHNTVDEHLDMLMVCHHLDSNIEEDVAFADSRIRKETIAAEDILHDRGAFSMISSDSQAMGRVGEVVTRTWQTAHKMKQQFGLLPEDQELGADNFRARRYIAKYTINPAIAHGISHEVGSIEPGKMADLVLWKPAFFAVKPSMIIKGGMIASAPMGDPNASIPTPQPVHYRPMFGSCGKAAAATSVTFVSKAALNNGLKESLGLERTLVACKNTRNISKLDMIHNDWLPNITVDPQTYEVRADGELLTCEPAETLPLAQLYTLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REMA_BACSU
Sequence: MTIKLINIGFGNIISANRMISIVSPESAPIKRMIQDARDRGMLIDATYGRRTRAVVVMDSDHIILSAVQPETVAHRLSVKEEIMDEGQG
What is the function of this protein?
Regulates the biosynthesis of the extracellular matrix and the biofilm formation (PubMed:19363116, PubMed:23646920).  Activates the transcription of the matrix biosynthesis operons eps and tapA-sipW-tasA.  Also activates expression of the opuA operon, involved in osmoprotection.  Acts by binding specifically to the promoter region of the target genes (PubMed:23646920).  Acts in parallel to the pathway that governs SinR derepression (PubMed:19363116, PubMed:23646920).  Required for endosporulation (PubMed:23396918).
What are the official names of this protein?
Extracellular matrix regulatory protein A, Regulator of extracellular matrix A.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: PSTB_BIFLO
Sequence: MGQRIDVNHENIYYGDFLAVEDVNINIEPNKVTAFIGPSGCGKSTVLRTLDRMHEIIPGAHVEGEVLLEGKNLYDKDVDPVAVRRDVGMVFQRPNPFPTMSIRENVLAGVRLNNHHLAKSDADDLVEWALRGANLWEEVKDRLDNPGIGLSGGQQQRLCIARAVAVHPQVLLMDEPCSALDPISTLAVEDLINELKSDYTIVIVTHNMQQAARIADYTAFFNLKAVGQPGHLEYFADTITMFNNPQNEEAERYISGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL4_PROMM
Sequence: MAECVVHDWQGKEAGKASLELKVSKETTAVDLMHRAVLRQQAHSRQGTASTLTRAEVRGGGRKPYKQKGTGRARQGTIRTPLRPGGGIIFGPKPRTYNLAMNRKERRLALRTALMARIEDVIVVKDFGNSLKVPKTREISDALIRLGLAADAKVLIILSTPSEIIRRSVRNLEKVKLIAADQLNVFDLLHANSLVLSEEALAKIQEVYGDD
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: FADI_YERPG
Sequence: MSKPLPLVTRQGDRIVIVNGLRTPFAKQATAYHGVPAVDLGKIVVSELLARSGISSELIDQLVFGQVVQMPEAPNIAREIVLGTGMSVHTDAYSVSRACATSFQAVANVAESIIAGSVDIAIAGGADSSSVLPIGVSKALARTLVDANKARSLSQKLKLFSRLRLRDLLPVAPAVAEYSTGLRMGDTAEQMAKTYGISREDQDALALRSHQLAAEAWQQGWLHDEVMTAYIPPYREAIIEDNNIRKDSILAQYAKLRPAFDRQHGSVTAANSTPLTDGAAAVLMMSESKAKALGLPPLGYLRSFAFSAIDVWQDMLLGPSYATPLALDRAGITLADLTLIDMHEAFAAQTLANLKMFASDTFAREKLGRSQAIGEVDMSKFNVLGGSIAYGHPFAATGARMITQTLNELRRRGGGLGLTTACAAGGLGAAMILEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEST_MYXXA
Sequence: MANITVFYNEDFGGKQVDLKPDEYKRDKLEALGIENNTISSVKVPPGVKAILYKNDDFTGDQIEVVANAEELGPLNNNVSSIKVMSVPVQPRARFFYKEQFDGKEVDLPPGQYTQAELERYGIDNNTISSVKPEGLKVVLFKNDNFSAGDTLSVTSNAPSLGAMNNNTSSIRITP
What are the official names of this protein?
Development-specific protein S homolog.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
What are the subcellular locations of this protein?
Spore, perispore. Note=Localized at the outermost layer of myxospores.
Protein: EGLB_NEOFI
Sequence: MKFGSIVLIAAAAGSAVAAPAKRASVFQWFGSNESGAEFGQNTIPGSYGKEFIFPDPSTISTLIGKGMNIFRVQFLMERLVPSSMTGSYNEEYLANLTSVVDAVTKAGSYAILDPHNFGRYNGQIISSTDDFKTFWQNLAGKFKSNNLVIFDTNNEYHDMDQALVLNLNQAAINGIRAAGATSQYIFVEGNSWSGAWTWVDVNDNLKALTDPQDKIVYEMHQYLDSDGSGTSESCVSTTIGKERVTAATKWLKDNGKVGIIGEFAGGVNDQCRTAISGMLEYLAQNTDVWKGALWWAAGPWWGNYMFNMEPPSGAAYVGMLDILEPYLG
What is the function of this protein?
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan.  Involved in the degradation of complex natural cellulosic substrates (By similarity).
What are the official names of this protein?
Probable endo-beta-1,4-glucanase B, Endoglucanase B, Carboxymethylcellulase B, Cellulase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_LACH4
Sequence: MADVVTMKQLLEAGVHFGHQTRRWNPKMAPYIFTQRNGIYIIDLQKTIKMLDDAYNFMKTVAEDGGVFLFVGTKKQAQDSIAEEATRAGQYYVNQRWLGGTLTNWTTIQSRVKRLKQLKEMSQDGTFDVLPKKEVALLTKEMDKLERFLGGIEDMPRIPDVLFVVDPKKEKIAVHEANILGIPVVAMVDTNTDPDPIDVVIPSNDDAIRAIRLIAGAMADAIVEGKQGQDDESVEVDFKKNADGSEEIVSAEENPED
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: GCSP_ESCF3
Sequence: MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGIGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGQKLRHAHYFDTLCVEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLDIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEIVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQNELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: GSA_SYNP6
Sequence: MVTSSPFKTIKSDEIFAAAQKLMPGGVSSPVRAFKSVGGQPIVFDRVKDAYAWDVDGNRYIDYVGTWGPAICGHAHPEVIEALKVAMEKGTSFGAPCALENVLAEMVIDAVPSIEMVRFVNSGTEACMAVLRLMRAYTGRDKIIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPKSTTANTLTAPYNDLEAVKALFAENPGEIAGVILEPIVGNSGFIVPDAGFLEGLREITLEHDALLVFDEVMTGFRIAYGGVQEKFGVTPDLTTLGKIIGGGLPVGAYGGKREIMQLVAPAGPMYQAGTLSGNPLAMTAGIKTLELLRQPATYEYLDQITKRLSDGLLAIAQETGHAACGGQVSGMFGFFFTEGPVHNYEDAKKSDLQKFSRFHRGMLEQGIYLAPSQFEAGFTSLAHTEEDIDATLAAARTVMSAL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR6_ARATH
Sequence: MASSLCVSNSTICPLPNVSSQPLLSFSHSLRPFISKSKPMCASIQKRDGSQFVVKSQALDFSGTFFEGGFGSDDDPTSPSGSGVSTALEDKPEPQCPPGLRQYETMAVLRPDMSEDERLGLTQKYEELLVAGGGMYVEVFNRGVIPLAYSIRKKNKAGETNTYLDGIYLLFTYFTKPESIVPLETVLTADDDIIRSSSFKIKKRKYN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6 alpha, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COAA_STREM
Sequence: MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDINDVIEVYLPLIHLIQIYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSRLLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVKGGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIYIDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENLEKFIEPTRNRAELILHKAADHKIDEIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_RHOPA
Sequence: MAGRTVTRVDLCEAVYQKVGLSRTESSAFVELVLKEITDCLERGETVKLSSFGSFLVRQKGQRIGRNPKTGTEVPISPRRVMVFKPSAILKQRINANGAMPMSTEESDENTAQSASGG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RS2_ALISL
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELAKIGNKKGKVLFVGTKRAASEAVKEAAINSDQYYVNNRWLGGMLTNFKTVRQSIKRLKEYEVQAQDGTFEQITKKEALMRTRSMEKLEKSLGGIKNMNGLPDALFVIDADHEHIAVKEANNLGIPVFAVVDTNSNPDGVDYIIPGNDDAIRAIQLYLNAAADSVKSGRNQDVAAAVAEKDGFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL19_RICB8
Sequence: MNIIDRFEQENISKLIENKKIPDFKAGDTVKVTVKIVDRSVEKDGKEKLTERFQAYEGVVIAKRNRGITSSFLVRKISHGEGVERRFMTYSPVVHAIDVVKYGVVRRAKLYYLRERSGKSARIKERHMHIAKKPKAKVAEAV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL1_STAAR
Sequence: MAKKGKKYQEAASKVDRTQHYSVEEAIKLAKETSIANFDASVEVAFRLGIDTRKNDQQIRGAVVLPNGTGKSQSVLVFAKGDKIAEAEAAGADYVGEAEYVQKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVKKAVEEIKAGKVEYRAEKAGIVHASIGKVSFTDEQLIENFNTLQDVLAKAKPSSAKGTYFKSVAVTTTMGPGVKIDTASL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RFP1_SCHPO
Sequence: MQFNGSNGIDESSVIDLTRSPSPPVETSISSTNIIDLDAIPDDSFPSSPVLSPRRRRMNRRRNERSRNFPSNHLSYLEDMIYLGPQVSTRRSSSRRDLMGMIARTFPEFSSVNSLSPSLFQLIVNRMRFDAIHPEWTNGSDDEYFSNHFEESYDDFTSSLENIKQSYKPPGPPKSGFTRSFNNDTLMVCPRCQEPLGTSKSKEKSALWATKCGHVYCGSCAKVLKTSKRSQSKCLVNDCGRYLNTKNAMWELFY
What is the function of this protein?
Mediates ubiquitination and subsequent desumoylation/degradation of sumoylated proteins and proteins containing SUMO-like domains.  Involved in maintaining genome stability where it acts in the cellular response to DNA damage.  Has a role in meiosis.
What are the official names of this protein?
E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp1, Meiotically up-regulated gene 140 protein, RING finger protein 1, RING-type E3 ubiquitin transferase rfp1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_STAAE
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKKVDEAYNFLKQVSEDGGQVLFVGTKKQAQESVKSEAERAGQFYINQRWLGGLLTNYKTISKRIKRISEIEKMEEDGLFEVLPKKEVVELKKEYDRLIKFLGGIRDMKSMPQALFVVDPRKERNAIAEARKLNIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTAKMADAILEGQQGVSNEEVAAEQNIDLDEKEKSEETEATEE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: GAG_HV1YF
Sequence: MGARASVLTGGKLDQWESIYLRPGGKKKYRMKHLVWASRELERFACNPGLMDTADGCAKLLNQLEPALKTGSEELRSLYNALAVLYCVHSRIQIHNTQEALDKIKEKQEQHKPEPKNPEAGAAAATDSNISRNYPLVQTAQGQMVHQPLTPRTLNAWVKVIEEKAFSPEVIPMFMALSEGATPSDLNTMLNTVGGHQAAMQMLKEVINEEAADWDRTHPVPVGPLPPGQLRDPRGSDIAGTTSTLAEQVAWMTANPPVPVGDIYRRWIVLGLNRIVRMYSPVSILEIKQGPKEPFRDYVDRFYKTLRAEQATQEVKNWMTETLLVQNANPDCKQLLKALGPGATLEEMMTACQGVGGPAHKARVLAEAMSQVQQPTTSVFAQRGNFKGIRKPIKCFNCGKEGHLARNCKAPRRGGCWKCGQEGHQMKDCKNEGRQANFLGKSWSPFKGRPGNFPQTTTRKEPTAPPLESYGFQEEKSTQGKEMQENQERTENSLYPPLTSLRSLFGNDPSSQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: CRE_STRHY
Sequence: MSVVALGATSITPPHGPESQGRPFPARGPVRPSARARPVPLWTYGYSEGTSRAGRRWG
What are the official names of this protein?
Curromycin resistance protein.
Protein: RLMKL_YERPP
Sequence: MNSLFASTARGLEELLKSELEALGAHDCKIVQGGVHFQGDDRLMYQSLLWSRLASRILLPLNEFKVYSDLDLYLGVQAIDWPSIFGVDKTFAVHFSGVNDEIRNSQYGALKVKDAIVDSFTRKMDQRPTVAKQQPDIRVNVFLQRDMASVALDLSGEGLHQRGYRDLTGQAPLKENLAAAIIQRSGWQPGTPMVDPMCGSGTLLIEAAMMASDRAPGLHRGHWGFTAWNAFNEALWRELTTEAQVRARRGLLETSSRFFGSDIDRRVIEMARANARRAGVAELITFNANDISKLVNPLPEGPVGTVISNPPYGERLESEPALIALHNMFGRMMKTAFGGWRLSLFSASPELLSCLQLRADREFKAKNGPLDCVQKNYQLTANPLGAGGALVAEDYANRLRKNVKKLDKWAKQQGIECYRLYDADLPDYNVAVDRYGSKVVVQEYAPPKTIDPQKARQRLFDVINATLAVLELPSNQLVLKTRERQKGKNQYEKLAQKGEFLLVSEYNAKLWVNLTDYLDTGLFLDHRIARQMLGKMSQGKDFLNLFAYTGTASVHAGLGGARSTTTVDMSRTYLEWAEKNLRVNGLTGQQHRLIQADCLSWLSNTDEQFDVIFIDPPTFSNSKRMETTFDVQRDHLVLMKELKWLLRRKGTIMFSNNKRGFQMDLAGIAALGLEAKEITALTQSEDFARNRQIHNCWLVTHSQEEK
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_LEUCK
Sequence: MTEILDGAAVAKLTNEKTANRVAKLGKPVTLAVIYDPQNDGSRLYVGMKSKKAAALGIQTKDIPTAADATTESVLALVASLNADPSITGILVQSPLAKGVKEREIFSAVAPHKDADGLGATVQGMLFGDALDDYTVAATPQGVMTLLKHYNIDIFGKQALVIGRSQLFGRPMFALLTNADATVTLAHRYTPENVLKDYLKRADIVVVGVGKPDFIQGSDLKPGAVVIDVGMNFVNGKAVGDVNFDSVQSIASYITPVPGGVGPMTIATLLENTITLAENYQA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MED31_CANGA
Sequence: MSDNKEDSTVDNSNSTEEVPLPTRFEVELEFVQSLANIPYVTYLLTQQQLLWKDPKFKNYLKYLEYWCEPPYAQCIVYPNALFILKLLNGFMEKATVNEDGLLDGLEDLPKVIQLQGNQWMNEMVERWAN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_RHOP5
Sequence: MAEAGARRPFFRRRKTCPFTGPNAPKIDYKDSKLLMRYVSERGKIVPSRITAVSAKKQRELARAIKRARFLGLLPYVIR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RL1_DESOH
Sequence: MAKKGKKIVAAQQKVDADRKYDISEGIDTALQARFAGFDESVDIAVRLGVDPRHADQMVRGSVVLPHGTGKEIKILVFAKGEKEKEALDAGADFVGNDELIEDIKNGWFGFDKAVATPDMMGAVGKIGKLLGPRGLMPNAKTGTVTFDVARAVNDLKAGKIDFRVDKAGIVHAPLGKASFGTEKLQDNMLALLRMLVAMKPATSKGAYMRSLAVSTSMGAGVRLDPLLVKDAVK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MURD2_XYLFT
Sequence: MRISALEGCRVALWGWGRESRAAYRAFRAAFPKQPLTLFCTIAEATEVQALADPVLSIETEVSVPRLAAFDVVIKSPGISPYSPLAVAATAAGAHFIGGTQLWFAAHADTDGVVPGAVCVTGTKGKSTTTALLAHLLRAAGHCTALAGNIGLPLLELLTPQPAPEYWAIELSSYQTADVAGSGARPALALVLNVFPEHLDWHGGEQRYINDKLSLVTVARPPIALLNAADPRLASLVLPQSDLRWFNQRDGWHVRGQVVYRGEQAVLDTALIPLPGAHNGSNVCAVLATLEALGLNAVALAPAACNFRPLPNRLQFLGERDGILWVNDSISTTPHATLAALDCFLGRRRVAVLVGGYDRGVNWECFAARITRKVPLDIVTMGANGPHIQALLAPLAAGRFGLHAAVDLPHAVALARTALGAQGGVLLLSPGAPSFGAYQDYVERGRHFAILAGFDPEVISSISGLGIA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase, UDP-N-acetylmuramoyl-L-alanyl-L-glutamate synthetase, UDP-MurNAc-L-Ala-L-Glu synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HACE1_XENLA
Sequence: MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVLELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKRGADPNYQDISGCTPLHLAARNGQKKCMSKLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTNVDVEDAMGQTALHVACQNGHKTTVLCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGETCDILIQHHPRLFQTLIQMTQNEELRENMLRQVLEHLSQQSEVQYLKILTGLAEVATTNGHKLLSISSSYEAQMKSLLRIVRIFCHVFRIGPSSPNNGNDMGYNGNKTPRNQVFKVRNVSDVFRKINIKEMNLPKHTLIYQATSEQDPLELLWHSLDEWLVLIATELTKNKRDSSNIACILLKQSPLDQQDISLAHQSAIGESGNHDHLLASTRAGDLESCSAIGIQEPVADGQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDEVLKCFVTRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKERCEWFYEHLLAGQPDTDMVHRPVNENDILLVHRDSIFRSSCEVVFKSNCEKLKQGIAVRFHGEEGMGQGVVREWFDILSSEMINPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGEILGLALYHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINGFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWMKNTEYTSGYERDDQVIQWFWEVVQELTQEERVLLLQFVTGSSRVPHGGFAYIMGGSGLQNFTIAAVAYTANLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
What is the function of this protein?
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases.  Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion.  Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division.
What are the official names of this protein?
E3 ubiquitin-protein ligase HACE1, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, HECT-type E3 ubiquitin transferase HACE1.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane. Cytoplasm. Endoplasmic reticulum.