PharMolix/UniProtQA huggingface dataset:
Protein: ENO_STRZP
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL27_SHEWM
Sequence: MAHKKAGGSTRNGRDSESKRLGVKRFGGESVLAGNIIVRQRGTKFHAGVNVGVGRDHTLFALTDGKVKFEVKGPNNRKFISIEG
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y443_MYCPN
Sequence: MHFIQPLQAFLQTKHIVEFSSIQQAVFKVWPRQNVVGIAETGSGKTFAYLLPALNQIDVTLNKPQAVVFVPTKELKWQILTILNDIKASFTGLKVSENFNSNAHLIVSLIGKDIILHETIKYVVFDEVDMFLEDSSQAEWINCVQLFQKHKPHFGFFSATLFNEQLQQIRKQVAPLTVVNQKKRAWKHSLVKHFLLNLNGQEPFAGLLALLNYHHNEQVLVFCSNAKSLKQLTSLLAHNQLSFKSLHGQLTPNERKHIFTSAANNTVRVLVVSDLLARGIDLPHFSVVISWDLPLVDSFYIHRSGRVARFNSWGNSYVFDLPHNQHKLTKFAHKGILFNSVHLERDGTLKFPQLKQSKQKPAVSSELKTAIKRIKAGYKKVKPNYKKRQKQQIAELFAKRKQRRSWKNF
What are the official names of this protein?
Probable ATP-dependent RNA helicase MG308 homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: YQGF_CAUSK
Sequence: MPVLDIAEFAAAIPDYLPIVGLDPGEKTIGVAVSDVTLTVASPLALIKKTKFSEDAATLFQLMGSRKAAGIVIGLPMNMDGTEGVRCQSNRALGRNLLRLQPHIPITFWDERLSTAAVTRVLIEEHDVNRKRRAEVVDKMAAAWILQGALERMRGIAEAAGKGF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROAP_OLEEU
Sequence: MSWQTYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVCGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-1, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: OSER1_PONAB
Sequence: MKSEAKDGEEESLQTAFKKLRVDASGSIASLSVGEGTGVRAPVRTATDDTKPKTTCASKDSWHGSTRKSSRGVVRTQRRRRSKSPVLHPPKFIHCSTIASSSSSQLKHKSQTDSPDGSSGLGISSPKEFSAGESSASLDANHTGAVVEPLRTSVPRLPSESKKEDSSDATQVSQASLKASDLSDFQSVSKLNQGTPCTCIGKECQCKRWHDMEVYSFSGLQSVPPLAPERRSTLEDYSQSLHARTLSGSPRSCSEQARVFVDDVTIEDLSGYMEYYLYIPKKMSHMAEMMYT
What are the official names of this protein?
Oxidative stress-responsive serine-rich protein 1, Oxidative stress-responsive protein 1, Peroxide-inducible transcript 1 protein.
Protein: DON1_YEAST
Sequence: MGKKNRKGKENNAAKTSFLKVENIKNTNSGLELPSQDYTNVEEKESSPKTDFPLITKEHVNTKTDSNILDYPTIGDLVSSVEKLCVLKELKIAFPEVDDTLIKAILIASQGVLEPAFNSLLYYSSPEENTDFALPMKPISVEDYSKINVSEILQREIFDDIEDEFSGQGINGSMVISKIESELSSLAEHIGNISTPGSNREVAESTRNVAVAEGHNTILSNEDSILKGKEKGKEEEKEKGEEKGVNSLKGAAVKVVAKSLKNNRIPVTVKRNEPSNNLFDVLNCDESEEEEEQDVETNTSNQERKNQGGNTEVPEAQRDSADRLPAKDDGGYKSAFGTDSCGLFAADAKDEKKQVHPSRQELSFT
What is the function of this protein?
Involved in the pathway that organizes the prospore membrane (PSM) during sporulation.
What are the official names of this protein?
Donuts protein 1.
What are the subcellular locations of this protein?
Prospore membrane. Note=Towards the end of meiosis I, or early stages of meiosis II, it forms circular structures above the meiotic plaque. As soon as an assembled prospore membrane is visible during meiosis II, it is detected at the leading edge, which cover the ring-shape opening of the PSMs. Probably recruited to the leading edges by ADY3.
Protein: ARGC_STAEQ
Sequence: MHISIVGITGYTGLELLRLALNHPHVTVSSIHATKEVGVQISDIFPHLKGIFDKEIQVFDSEFIMTHSDLVFFATPSGVAKDLSKNFVKNNFPVIDLSGDHRLSPDVYLKWYKKSPCTVDIQKRFTYGLSEVMNISHRNRFIANPGCYATATELALYPIISNHLIRVDSIIVDAKSGLTGAGKKLNQSSHYVNVNNNYVTYKLNKHQHIPEIVQTLQFFNKSLQNIQFSTSLIPVNRGIVATIYTRLENGVKINQIESTYKDVYKNKPFIRIKDGLPQLNEVIGTNYTDIGFVYNETTGVLTISSVIDNLIKGAAGQAIQNMNLMFNFDETDGLILAPLYI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P5CR_STAAW
Sequence: MKLVFYGAGNMAQAIFTGIINSSNLDANDIYLTNKSNEQALKAFAEKLGVNYSYDDATLLKDADYVFLGTKPHDFDALATRIKPHITKDNCFISIMAGIPIDYIKQQLECQNPVARIMPNTNAQVGHSVTGISFSNNFDPKSKDEINDLVKAFGSVIEVSEDHLHQVTAITGSGPAFLYHVFEQYVKAGTKLGLEKEQVEESIRNLIIGTSKMIERSDLSMAQLRKNITSKGGTTQAGLDTLSQYDLVSIFEDCLNAAVDRSIELSNVEDQ
What is the function of this protein?
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR, PCA reductase.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAFD_ECO55
Sequence: MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERIRILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFVLPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNFSLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTDDQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK
What are the official names of this protein?
UPF0294 protein YafD.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PJVK_HUMAN
Sequence: MFAAATKSFVKQVGDGGRLVPVPSLSEADKYQPLSLVVKKKRCFLFPRYKFTSTPFTLKDILLGDREISAGISSYQLLNYEDESDVSLYGRRGNHIVNDVGINVAGSDSIAVKASFGIVTKHEVEVSTLLKEITTRKINFDHSLIRQSRSSRKAVLCVVMESIRTTRQCSLSVHAGIRGEAMRFHFMDEQNPKGRDKAIVFPAHTTIAFSVFELFIYLDGAFDLCVTSVSKGGFEREETATFALLYRLRNILFERNRRVMDVISRSQLYLDDLFSDYYDKPLSMTDISLKEGTHIRVNLLNHNIPKGPCILCGMGNFKRETVYGCFQCSVDGQKYVRLHAVPCFDIWHKRMK
What is the function of this protein?
Peroxisome-associated protein required to protect auditory hair cells against noise-induced damage.  Acts by regulating noise-induced peroxisome proliferation in auditory hair cells and neurons, and promoting autophagic degradation of damaged peroxisomes (pexophagy).  Noise overexposure increases reactive oxygen species (ROS) levels, causing oxidative damage to auditory hair cells and resulting in hearing loss.  PJVK acts as a ROS sensor that recruits the autophagy machinery to trigger pexophagy of peroxisomes damaged by oxidative stress.  In addition to pexophagy, also required to promote peroxisome proliferation in response to sound overstimulation.
What are the official names of this protein?
Pejvakin, Autosomal recessive deafness type 59 protein.
What is the protein family that this protein belongs to?
Belongs to the gasdermin family.
What are the subcellular locations of this protein?
Peroxisome membrane. Cell projection, cilium. Note=Associates with the peroxisomal membrane; it is unclear whether it is embedded or just associated with the peroxisomal membrane. Localizes to ciliary rootlet.
Protein: RL31_SPHAL
Sequence: MKKDIHPDYHMITVKMTDGTEYQTRSTWGSEGDVMTLEIDPTAHPAWTGGQGRMLDSGGQVAKFNKRFGGLTLKR
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ASSY_PROMM
Sequence: MGRAKKVVLAYSGGVDTSVCIPYLKHEWGVEEVITFAADLGQGDELDPIRLKALDAGASQSLVGDLIEPFVEQFALPAIRANALYEGRYPLSTALARPLIARQLVEVAREVGADAVAHGCTGKGNDQVRFDLAIAALAPDLKVLTPAREWSMSREEAIAYGERCGIPAPVSKKSPYSIDLNLLGRSIEAGPLEDLMVAPPEEVFAMTSSIDAAPSQAQDIEISFEAGNPVAIDGVRLDSVGLIKEANRLAGRHGFGRLDIIENRVVGIKSREIYETPGLLLLIRAHQELESLTLAADVLRMKRQLEMQWAELVYQGLWFSPLKDALDGFMDRTQTYVNGLVRIRLQKGNAMVIGRSSDTNSLYISEMATYGSEDNFDHRAAEGFIYIWGLPSRLWAAARRG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYR_STAAU
Sequence: MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
What are the official names of this protein?
Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: MUTS_SYNJA
Sequence: MDPALLTPMMQHYVELKRQYPHAILLYRLGDFYEMFFQDAQLVSRELELVLTGREAGAIGRVPMCGIPYHAFDRYAAQLVAKGYALAVCDQMEPADQAKGLVRREVTRVITPGTVIEEELLQARQNNYLAAIVRLRGSKQTVWGLAYADISTGEFWVCQGEGQEQLEQELARLQPAEILLPTEEGLGLGLMRPGDPQAPLGLPGQYTYTLRPAEPFELATARENLLQTYGLRSLEGLGCEGLPLAIRAAGGLLHYLEETQKNLVQPSPQGGHPLLRPPRTYQLTDYLILDTQTRRNLELTQTIREGAFVGSLLWVLDRSRTAMGGRTLRRWLLQPLRDPEQIRLRQDTIQELLESPSLRTRLGSLLDSLYDLERLANRVASGTANPRELVALGSSLGKLPQLAELVAEAQTPLLQSLQQVDPALVDLGHRIEHTLLPSPPPVLTEGGLIRPGVDAELDRLRQQVEQDRHWIAQLEKTERERTGIPTLKVGFNKAFGYYLSISRAKAQQVPKEYIRKQTLTNEERFITPELKEKEARILTAQTEINQREYELFVQLRQEAGSQAAAIRQVAQTLAAVDALFGLAEVAVQQGYTRPVITADRRLIIEEGRHPVVEKSLPQGLFVPNSVRLGSPHGPDLIVLTGPNMSGKSTYLRQIGLIQILAQMGSFVPARRAELGLCDRVFTRIGAVDDLATGQSTFMVEMNETANILNHAGERSLVLLDEIGRGTATFDGLSIAWAVAEYLATQVRARTIFATHYHELNQLETLLPNVANFQVVVKELRDRIIFLHQVQPGGADRSYGIEVGRMAGLPQPVIERAKQVLALVEQHSRIGLGLRSQGKSRPSSNNPKKRFKQESNSRGIPDCDAKAGDQLSLIPTSLYPEEL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL27A_BOVIN
Sequence: MPSRLRKTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGMHHHRINFDKYHPGYFGKVGMRHYHLKRNQSFCPTVNLDKLWTLVSEQTRVNAAKNKTGAAPIIDVVRSGYYKVLGKGKLPKQPVIVKAKFFSRRAEEKIKGVGGACVLVA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L27a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_ACIB5
Sequence: MKIVADENLAFTDYFFSEFGDIQHKAGRTLTHTDVQDAEALLVRSVTAVNESLIQNTALKYVGSATIGTDHLDIQALEKHGITWANAAGCNAQAVAEYVITALLHLDASLLEQQEKFTLGIVGLGNVGKRLVYMAQLLGWKVIGFDPYVQLDSIENVSFQALLQQANAVSIHVPLTKKGEHATYHLFDEKAFAALQPNTILINSARGPVVKEAALIEDIQRTQRKVVLDVFEHEPVISEELLNMLALATPHIAGYSLEGKARGTQMIYEAFCQKFGYEINKRFETQLPACEDYFSGHDLKAVLKQKLSQIYDIAQDDANIRACVKEGKVEQKAFDLLRKNYPLRREWAAHGGPQA
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADM_METM6
Sequence: MRAFLIGRWQPFHKGHLEIIKKISKEVDEIIIGIGSCQKSHTLTDPFTAGERMMMITKTLENYDINYYAIPINDIDYNAVWVSCVESLTPPFTTIYTGNSLVRELFSEKNYNVKKPELYNRTDYSGTKIRKKMLDGSNWEHLVPEEVVKVIEEIDGINRIRRLSEKDYDEE
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PACC_CANAL
Sequence: MNYNIHPVTYLNADSNTGASESTASHHGSKKSPSSDIDVDNATSPSSFTSSQSPHINAMGNSPHSSFTSQSAANSPITDAKQHLVKPTTTKPAAFAPSANQSNTTASQSYTQPAQQLPTQLHPSLNQAYNNQPSYYLHQPTYGYQQQQQQQQQHQEFNQPSQQYHDHHGYYSNNNILNQNQPAPQQNPVKPFKKTYKKIRDEDLKGPFKCLWSNCNIIFETPEILYDHLCDDHVGRKSSNNLSLTCLWENCGTTTVKRDHITSHLRVHVPLKPFHCDLCPKSFKRPQDLKKHSKTHAEDHPKKLKKAQRELMKQQQKEAKQQQKLANKRANSMNATTASDLQLNYYSGNPADGLNYDDTSRKRRYENNSQHNMYVVNSILNDFNFQQMAQAPQQPGVVGTAGSAEFTTKRMKAGTEYNIDVFNKLNHLDDHLHHHHPQQQHPQQQYGGNIYEAEKFFNSLSNSIDMQYQNMSTQYQQQHAGSTFAQQKPTQQASGQLYPSLPTIGNGSYTTSGSSHKEGLVNNHNGYLPSYPQINRSLPYSSGVAQQPPSALEFGGVSTYQKSAQSYEEDSSDSSEEDDYSTSSEDELDTLFDKLNIDDNKVEEVTIDGFNLKDVAKHREMIHAVLGYLRNQIEQQEKEKSKEQKEVDVNETKLYPTITAF
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes.  Specifically recognizes and binds the consensus sequence 5'-CCAAGAA-3'.  Required for the control of alkaline pH-induced filamentation (dimorphic switch) and virulence.
What are the official names of this protein?
pH-response transcription factor pacC/RIM101, pH-response regulator protein 2.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACP_DESVM
Sequence: MSVEEKISKIIMDQLGVSAEEVKPEASFVEDLGADSLDLTELIMAMEEEFGIEIDDDDAQKILKVQDAIAYIKNKQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHDC_BACCN
Sequence: MSEAAKTLDGWYCLHDLRSIDWVSWKTLSSEEREQAIVEFLNIIEKWNKVAAEKQGSHAMYTIVGQKADIMFMLLRPTMEELNEIETELNKTTLAEYMIPAYSYVSVVELSNYLPADEDPYQNPQILARLYPELPTANHICFYPMDKRRQGNDNWYMLPMEERKKLMYSHGKIGRQYAGKVRQVITGSVGFDDYEWGVTLFADDVLQFKKLVYEMRFDEVSARYGEFGTFFVGNILPSEKVTSFLHV
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: RL7_MYCA9
Sequence: MAKLSTEELLDAFAELTLLELSEFVKAFEEKFEVTAAAPVAVAAVGGAAPAAADAAEEQSEFDVILESAGDKKIGVIKVVREIVSGLGLKEAKDLVDGAPKPLLEKVAKEAADDAKAKLEAAGATVTVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SLYX_ECO27
Sequence: MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: RLME_BRUAB
Sequence: MSKAGGNKGGSRTGGRGGAGSSNLHVRVKKKAGTIKESSRRWLERHLNDPYVHKSRQDGYRSRAAYKLIEINDRYNLLKKGQKIIDLGAAPGGWSQIAARIVGSTDENPQVVGIDYLHVDPLPGVILLEMDFLDDEAPQKLMDALGDKPDLVISDMAAPTTGHRRTDHLRTVHLCEVAADFAVSVLKPGGHFLTKTFQGGTENELLALLKQKFRSVHHVKPPASRAESVELYLLARDFKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHP5_ORYSJ
Sequence: MEYGNLRRQAASLKKSLFDQGYLDEQFCQVEDLQDEANPNFAEEVVSLFFKDSTRVMLNFEQAIEKHPKDFARWDTHMQQLKGSCSSIGASRVKNECTSFRNFCGEENAEGCTRSFQKVKREHAVLRQKWESYFQLLRQAGPAGTATRPAGK
What is the function of this protein?
Functions as two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs).  Plays an important role in propagating cytokinin signal transduction.
What are the official names of this protein?
Pseudo histidine-containing phosphotransfer protein 5, OsHpt5.
Protein: PDXH_THEVB
Sequence: MTRIADLRRDYRRQRLLESDAAEDPIEQFRLWLTDAVNAELPEPNAMTLATVGLDGMPAARLVLLKEVDDRGFVFFTNYRSRKGRELAAHPKAALVFWWAELERQVRIEGNVEQISAAESDAYFQSRPLGSRWGAWASQQSEVLASYAELEARLAAVEAHYGENVPRPEHWGGYRVLPTLIEFWQGRPNRLHDRLCYRRQGDHWQRVRLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: PHNC_ALCFA
Sequence: MLEIHNLQKSYSTGDKALKGVNLSVQPGELLGLIGPSGAGKSTLIRCVNRLVEPSEGRVLLNGKDLANLGRHDLRMARRRIGMIFQEYALVERLTVMENLLSGRLGYSGFWPSWFRRFSPEDIRLAYALLERVGLDGMHNKRADALSGGQRQRVGIARALMQKPDLLLVDEPTASLDPKTSRQVMRLVLELCREHGLSAIINIHDVVLATEYLPRIVGLRAGAVVYDGPASAIDTHVLTRIYGAEDWSSITDRMTGTTVPGDEQAARVATIAIAAE
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYT_UREU1
Sequence: MYKFDPKLNHSAAHVLAMALTKFYPNLSLAIGPAIDEGFYYDFNLNDPNTSITPIDLLKIEKEMKKIAAQALTFDYEQVSYEQAKDLFKNNKYKLDIIEENKNKPLSIYHSGKWFDLCKGPHVENTKEIKAIKLLNIAGSYWRGDANNDQLIRIYGVAFNDQAQLDAYLVDLQERKERDHRKIGKDLNLFTFNNLAGQGLPIWLPNGTIIKSQVQKFINEVEFQFNFDTVITPILGSIDLYKTSGHWDHYKDNIFSPVQIDNEVLILRPMTCPHHTLVYSNELRSYRSLPIRLSEHSILHRYESSGGLTGFERVREMILEDCHVFCRPDQIEHEVINAFKMIQEAQEGLGIKTFEIHLSLNDPNDKEKYYDDPQMWEHSQNALRKMLKDHKIPYKEMVGEAAFYGPKIDFQVKTVLNRIITVSTIQLDFLLPNRFNLSYINENNEQSTPVMIHIGIIGTYERLLAILLEQTKGVLPLWLSPVQVVIIPVNENLHADYAKELNAKLRKHLVRSSLDLRNERLSKKIREAQIQKIPYQIVVGDEEIKNDKMVTYRRYGSEETTTVSVDDFIKVLENDIRSKK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROKB_THEMA
Sequence: MRIFLVGMMGSGKSTIGKRISEVLDLQFIDMDEEIERREGRSVRRIFEEDGEEYFRLKEKELLKELVERDNVVVATGGGVVVDPENRELLKKEKTLFLYAPPEVLMERVTTENRPLLSEGKERIREIWEKRKQFYAEFRRIDTSRLNEWETTALVVLEALDEKEISTIEKPHLVKIILGGFKRVRNEELVFTTERVEKIYGRYLPENRLLFPDGEEVKTLEHVSRAYYELIRMDFPRGKTIAGVGGGALTDFTGFVASTFKRGVGLSFYPTTLLAQVDASVGGKNAIDFAGVKNVVGTFRMPDYVIIDPTVTLSMDEGRFEEGVVEAFKMTILSGRGVELFDEPEKIEKRNLRVLSEMVKISVEEKARIVMEDPYDMGLRHALNLGHTLGHVYEMLEGVPHGIAVAWGIEKETMYLYRKGIVPKETMRWIVEKVKQIVPIPVPSVDVEKARNLILNDKKILKGSRVRLPYVKEIGKIEFLEVDPLELLEVVD
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Bifunctional shikimate kinase/3-dehydroquinate synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPT_CERS4
Sequence: MRHTLPIAPQFYVTAPQSCPYLEGRLERKLFTALQGEHAQKLNDTLSKQGFRRSQNVLYRPSCAECSACLSARIRVADFEPTRTQRRVMKRNADLRRNATSPWATEDQYALFRRYLDDRHADGGMADMDIFEFAAMIEETPIRSRVIEYSRPGDTPSNRPLSAVCLTDIFDDGLSMVYSFYDPDLAGRSLGAYVILDHIEIAREAGLPYVYLGYWVPGSRKMGYKATYSALEIYKGGRWQAIGQPSDHRAELHPLSVDPIAEQVARISLPEARSGDRSRD
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_HIPAM
Sequence: MAYPLQLGFQDAVSPIMEELLYFHDHTLMIVFLISSLVLYIITLMLTTKLTHTNTMNAQEVETVWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMVPTSDLKPGDLRLLEVDNRVVLPMDVTVRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMSTRPGLFYGQCSEICGSNHSFMPIVLELVPLQTFEKWTASLL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.