PharMolix/UniProtQA huggingface dataset:
Protein: ADA2_CANAL
Sequence: MDSRTKLFHCDVCSSDCTNRIRIQCAICTDYDLCVPCFAAGLTTGDHKPWHDYQIIEQNTYPIFDRDWGADEELLLIQGCETSGLGNWADIADHIGNRSKEEVAEHYFKIYLESKDYPLPEMNKDFTDVSPLQFLEERKERLEKRKNIPLPPPRGKPVASVPLCHEIQGYMPGRLEFDHEAENEAEIPIKDMVFDPEDSANDIDLKLTILDIYNSRLTTRAERKRVMILNHLLDYRKNIGSDKRKSKEEKDLLKKINAFIRILTPEDFESFSRDLLTELKCRMKIQQLQTWRRNGITTLEDGAKFEKDKVIRAAHYQRMGNGTGSGRHSQTPGLTNGNSFNGNGHRNKFSPQPEFRSKSTTARAPLDISHAADFELLSAEEKQLCATLRILPKPYLAIKNQLMREAVKNNGVLKKKDARQALKIDVNKASKIYEFFVHMGWCSQG
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA.  SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation.  ADA preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B.  Required for expression of many CAS5-dependent genes.  Plays a key role in cell wall integrity, cell adhesion, hyphal development and pathogenesis.
What are the official names of this protein?
Transcriptional adapter 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SDP1_ARATH
Sequence: MDISNEASVDPFSIGPSSIMGRTIAFRVLFCRSMSQLRRDLFRFLLHWFLRFKLTVSPFVSWFHPRNPQGILAVVTIIAFVLKRYTNVKIKAEMAYRRKFWRNMMRTALTYEEWAHAAKMLEKETPKMNESDLYDEELVKNKLQELRHRRQEGSLRDIMFCMRADLVRNLGNMCNSELHKGRLQVPRHIKEYIDEVSTQLRMVCNSDSEELSLEEKLSFMHETRHAFGRTALLLSGGASLGAFHVGVVRTLVEHKLLPRIIAGSSVGSIICAVVASRSWPELQSFFENSLHSLQFFDQLGGVFSIVKRVMTQGALHDIRQLQCMLRNLTSNLTFQEAYDMTGRILGITVCSPRKHEPPRCLNYLTSPHVVIWSAVTASCAFPGLFEAQELMAKDRSGEIVPYHPPFNLDPEVGTKSSSGRRWRDGSLEVDLPMMQLKELFNVNHFIVSQANPHIAPLLRLKDLVRAYGGRFAAKLAHLVEMEVKHRCNQVLELGFPLGGLAKLFAQEWEGDVTVVMPATLAQYSKIIQNPTHVELQKAANQGRRCTWEKLSAIKSNCGIELALDDSVAILNHMRRLKKSAERAATATSSSHHGLASTTRFNASRRIPSWNVLARENSTGSLDDLVTDNNLHASSGRNLSDSETESVELSSWTRTGGPLMRTASANKFIDFVQSLDIDIALVRGFSSSPNSPAVPPGGSFTPSPRSIAAHSDIESNSNSNNLGTSTSSITVTEGDLLQPERTSNGFVLNVVKRENLGMPSIGNQNTELPESVQLDIPEKEMDCSSVSEHEEDDNDNEEEHNGSSLVTVSSEDSGLQEPVSGSVIDA
What is the function of this protein?
Involved in the release of fatty acids from the oil body in germinating seedlings (PubMed:16473965, PubMed:19136267, PubMed:27466365).  Can hydrolyze triacylglycerols and diacylglycerols but not monoacylglycerols, phospholipids, galactolipids or cholesterol esters (PubMed:16473965, PubMed:19136267).  SDP1 lipase activity is required to limit triacylglycerol accumulation in roots, leaves and stems, which are vegetative tissues (PubMed:23686420).  Functions synergistically with PDAT1 in regulating fatty acid flow from membrane lipid synthesis toward peroxisomal beta-oxidation through a transient triacylglycerol pool (PubMed:25293755).
What are the official names of this protein?
Triacylglycerol lipase SDP1, Protein SUGAR-DEPENDENT 1.
What is the protein family that this protein belongs to?
Belongs to the PLPL family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Peripheral membrane protein. Peroxisome. Note=Associates with the oil body membrane (PubMed:16473965). Migrates from peroxisomes to the oil body surface through peroxisomal tubulation (PubMed:25775518).
Protein: TCMO_VIGRR
Sequence: MDLLLLEKTLLGLFLAAVVAIVVSKLRGKRFKLPPGPLPVPIFGNWLQVGDDLNHRNLTQLAKRFGDIFLLRMGQRNLVVVSSPDLAKEVLHTQGVEFGSRTRNVVFDIFTGEGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRHGWEAEAAAVVDDVRKNPDAAVSGLVIRRRLQLMMYNNMYRIMFDRRFESEEDPLFQRLKALNGERSRLAQSFEYNYGDFIPILRPFLKGYLKICKEVKETRLKLFKDYFVDERKNIGSTKSTNNEGLKCAIDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKVRDEIDRVLGVGHQVTEPDIQKLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPAHWKKPEEFRPERFFEEESHVEANGNDFRYLPFGVGRRSCPGIILALPILGITLGRLVQNFELLPPPGQSQIDTSEKGGQFSLHILKHSTVVAKPRSF
What is the function of this protein?
Catalyzes the first oxidative step of the phenylpropanoid pathway in higher plants by transforming trans-cinnamate into p-coumarate (By similarity).  The compounds formed by this pathway are essential components for lignification, pollination, and defense against ultraviolet light, predators and pathogens (By similarity).
What are the official names of this protein?
Trans-cinnamate 4-monooxygenase, Cinnamic acid 4-hydroxylase, C4H, CA4H, Cytochrome P450 73, Cytochrome P450C4H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FMP46_SCHPO
Sequence: MFGLTTKRILTLFTKKRQTLVEQKLTEYMIAGEKTDNQMLHFKLQVETATPTLDQLNIMLSNIGKDKSDLLVAGATSIEDALTKYQHDNQLFRRPCLVDWDKGKVSPYSILLQTRDFSKLL
What is the function of this protein?
Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.
What are the official names of this protein?
Putative redox protein fmp46, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FMP46 family.
Protein: NUOD_NOCSJ
Sequence: MADQDLYSGSSETTEGRVFTVTGQDWDSIAEGLAEDEAQERIVVNMGPQHPSTHGVLRLILELEGETVTEARAGIGYLHTGIEKNMEYRTWTQGVTFCTRMDYLSPFFNEMTYVLGIERLLDIEDRVPEKAQVMRVLLMELNRISSHLVAIATGGMELGALTVMTIGFRERELVLDLFELITGLRMNHAFIRPGGVAQDMPPGALDEIRGFVALMKKRLPEYADLCNANPIFKGRLEGIGHLDLAGCLALGLTGPVLRSTGYPWDLRKTQPYCGYETYDFDVQTWDTSDSYGRFRIRLNEMWESLRIIEQAADRLAGLDGAPVMIEDKKIGWPSQLAIGSDGMGNSLDHIRHIMGESMEALIHHFKLVTEGFRVPPGQAYVPVESPRGELGAHVVSDGGTRPFRAHFRDPSFTNLQATSVMAEGGMVADVIVAIASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HIS4_PECAS
Sequence: MIIPALDLIDGQVVRLHQGDYGQQRQYGSDPLPRLQDYQQQGAGVLHLVDLTGAKNPSARQIPLLTTLLAGVSVPVQIGGGIRTEQDVEALLKAGASRVVIGSTAVKQPELVQQWFTRYGAEALVLALDVRIDANGTKYVAISGWQENSDATLEQIVEQYLPFGLKHVLCTDISRDGTLSGSNVELYREISQRYPQIAFQASGGIGNLTDIANLRSSGVQGVIVGRALLEGKFNVAEAISCWQNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COG5_BOVIN
Sequence: IGALQGAVDRVLTQPTQSIVRNVAVVNSLYK
What is the function of this protein?
Required for normal Golgi function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 5, COG complex subunit 5, 13S Golgi transport complex 90 kDa subunit, GTC-90, Component of oligomeric Golgi complex 5.
What is the protein family that this protein belongs to?
Belongs to the COG5 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein.
Protein: MOF1_ORYSJ
Sequence: MGSGGGGCGRNGAVRQYIRSKVPRLRWTGELHCSFVQAIEFLGGQDKATPKLILQLMGVKGLTISHVKSHLQMYRCSRLGSHGTGRRSEMQPQLQRKHSCGADEQVPREFLCPPLKRTRMGTEATYKGMQGSQGISEMRTTGTQYCIDDYMQAMAMERRIKEEGLRWQRDAAAAAAADGGAAASNLQTVGCSVQESDPFKIIKPEVHHLGPVLKLQCSKVENSGFISSSTGTAARDQPEPPPLEKCSLSLSLGPDPKCMPAIASSPSESSCILSSSSRSFSDCSGNSGCLVAPGVNLELSMSICGS
What is the function of this protein?
Transcriptional repressor that plays a role in the regulation of organ identity and spikelet meristem determinacy (PubMed:32680975).  Interacts with the TPR corepressors to possibly repress the expression of downstream target genes (PubMed:32680975).
What are the official names of this protein?
Myb family transcription factor MOF1, Protein MORE FLORET 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPG_LACCB
Sequence: MAESLMDIKRKIASTKKTGQITQAMQMVSGAKLSQIEKRAKKYQIYSDKVRQIVTHLAAGQLLELANAAESDTDSGDKSQVISVASLLQKRPVKKTGYLVITSDRGLVGSYNSTVLKAMMQMIKDDHESPDDYVMMAIGGVGADFFKARGLNLAYEYRGVSDIPTFNEVREIVKTAVTMFDNGVFDELYVCYNHHVNTLTSAFRAEKMLPISDLDVSEVADTNVEYLIEPDLDSVLESVLPQYAESLIFGAIMDAKTAEHAASTTAMRSATDNANDLISHLSTQYNRARQAAITTEITEIVGGAAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RAD54_DROAN
Sequence: MRRSLAPSQRIGQSTASRNAFTPPLLQKKNKRACQKDLRLDTDADEDKERKRFGLRDATNSEIPLPIRFTANSAYELAIAQVLARKFKVPIDNYVPDYGGNRCLGVRRVVVRRPLHDPQACNALVLFQPPNYTEHERMSMDPSKVLVHVVVDPLLSNILRPHQREGVRFMYECVEGKKGDFNGCIMADEMGLGKTLQCVTLVWTLLRQGPESKPTINKAIVVSPSSLVKNWEKEFTKWLQGRLLCLAMEGGTKENTIRVLEQFSMTSSKLGTPVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYFSLVNFVNPEMLGTAADFKRNFENSILRGQNADSTEGERKKAIEKTQELIGLVDQCIIRRTNQILTKYLPIKFEMVICVKLTAIQLQLYTNFLNSDQVRRSLADCNEKASLTALADITTLKKICSHPDLIHQKIEAKEKGFENSQNVLPSNYKPKEICPEWSGKFMLLDFMLAAIRAAGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDKFNDPDSECFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGTIEEKILQRQTHKKSLSSTIIDNNESSEKHFTRDDLKDLFSFDQKILSDTHEKLKCKRCVQNIQTKPPSESTDCTSHLSQWYHCSNNRGLPDSILAQAWTDSKCVSFVFHHRSQAKEVVESPESAAAEAESVEEESQPTQRKRPSPPLSDDSADEDFIGF
What is the function of this protein?
Involved in mitotic DNA repair and meiotic recombination.  Functions in the recombinational DNA repair pathway.  Essential for interhomolog gene conversion (GC), but may have a less important role in intersister GC than spn-A/Rad51.  In the presence of DNA, spn-A/Rad51 enhances the ATPase activity of okr/Rad54 (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RAD54-like, Protein okra.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATL41_ORYSJ
Sequence: MASSAPAWVPYEPTRDCSQGLCSMYCPQWCYFIFPPPPPFDVAGTSADDSSGPVFSPLVIAIIGVLASAFLLVSYYTFISKYCGTVSSLRGRVFGSSSGGAAYGGGAGSGGRHGHGQSRSHESWNVSPPSGLDETLINKITVCKYRRGDGFVHTTDCSVCLGEFSDGESLRLLPRCSHAFHQQCIDTWLKSHSNCPLCRANITFVTVGLASPEPEGCAPGETGGDNTHEVVVVMDGLENLCEEQQEAVSRASTADDDHDAKDVAEGMEEANGAAEIREEGSPPKRGASSFDLHRDNRMCIADVLQESMEDELTAARESGLLAGGAGTSRRCHGENSKGRGGRSRRALQLQDAMEALPGKRLPSGGRSCFSSKSGRGKDSDHPM
What is the function of this protein?
Possesses E3 ubiquitin-protein ligase in vitro.
What are the official names of this protein?
E3 ubiquitin-protein ligase Os04g0590900, RING-H2 finger protein Os04g0590900, RING-type E3 ubiquitin transferase Os04g0590900.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YSCS_YERPS
Sequence: MSQGDIIHFTSQALWLVLVLSMPPVLVAAVVGTLVSLVQALTQIQEQTLGFVIKLIAVVVTLFATASWLGNELHSFAEMTMMKIQGIR
What is the function of this protein?
Component of the Yop secretion machinery.
What are the official names of this protein?
Yop proteins translocation protein S.
What is the protein family that this protein belongs to?
Belongs to the FliQ/MopD/SpaQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CFP32_MYCTO
Sequence: MPKRSEYRQGTPNWVDLQTTDQSAAKKFYTSLFGWGYDDNPVPGGGGVYSMATLNGEAVAAIAPMPPGAPEGMPPIWNTYIAVDDVDAVVDKVVPGGGQVMMPAFDIGDAGRMSFITDPTGAAVGLWQANRHIGATLVNETGTLIWNELLTDKPDLALAFYEAVVGLTHSSMEIAAGQNYRVLKAGDAEVGGCMEPPMPGVPNHWHVYFAVDDADATAAKAAAAGGQVIAEPADIPSVGRFAVLSDPQGAIFSVLKPAPQQ
What is the function of this protein?
May function as a glyoxylase involved in the methylglyoxal detoxification pathway.  Induces maturation of dendritic cells in a TLR2-dependent manner, causing increased expression of cell-surface molecules (CD80, CD86, MHC class I and II) and pro-inflammatory cytokines (TNF-alpha, IL-6, IL-1 beta and IL-12p70).  Acts via both the NF-kappa-B and MAPK signaling pathways.  Induces Th1-polarized immune responses.
What are the official names of this protein?
Putative glyoxylase CFP32, 27 kDa antigen Cfp30B.
What are the subcellular locations of this protein?
Secreted.
Protein: IPYR_RHILO
Sequence: MRIEAIATGKNPPEDVNVIIEVPIGGEPIKYEMDKEAGTLFVDRFLHTSMRYPGNYGFVPHTLSGDGDPIDVLVCNTRALVPGCVINVRPIGVLVMEDNAGQDEKVIAVPSPKLTLRYENVTEYTHLPEITRQQVQHFFEHYKDLEPGKWVKIEGWHDSKYAKKMIVDAIERAKKGK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21A_ANAVA
Sequence: MTQIVVGENEHIESALRRFKREVSKAGIFQDMRKHRHFETPIEKSKRKKLALHKQSKRRFRT
What are the official names of this protein?
30S ribosomal protein S21 A.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ECFA1_STRMU
Sequence: MTDKIIELKNVTFRYDENQEKPTLNNISFHVKHGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQILIEGHKLSEDNVWDIRHKISMVFQNPDNQFVGATVEDDIAFGLENKGIPLKEMRERVVEALNLVDMSDFKTREPARLSGGQKQRVAIAGAVAMRPSIIILDEATSMLDPEGRLELIGTIQKIREQYGMTVISITHDLDEVTLSDRVLVMKNGQIESSSSPRELFSRGDELLDLGLDIPFTSTIIKALRQIGFTFDNRYLLEKELEDKLWALISKK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSBL_OENAR
Sequence: MTQSNPNEQDVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YAJQ_SHISS
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDASKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: DNAE2_VIBPA
Sequence: MSYAELFCQSNFSFLTGASHAEELVLQAAFYRYHAIAITDECSVAGVVKAHATIEQHKLDIKQIVGSMFWLNEECQIVLLCPCRKAYAEMCRIITNARRRSEKGSYQLSEWDLMSIRHCLVLWLPTHQASDHYWGRWLNQHHNNRLWVAIQRHLGGDDDAYTNHCEKLAHELQQPITACGGVLMHTAERLPLQHILTAIKHGCSVDQLGFERLSNAERALRPLNKLVRIYKPEWLEESKYIADLCEFKLSDLKYEYPTELIPNGYTPNSYLRMLVEQGKERRFPEGVPEDINQTIENELRLIEDLKYHYYFLTIHDIVMFAKQQGILYQGRGSAANSVVCYCLEITAVDPRQISVLFERFISKERKEPPDIDVDFEHERREEVIQYIYKKYGRERAALAATVISYRFKSAVREVGKALGIEETQLDFFIKNVNRRDRSQGWQAQIIELGLQPESLKGQQFIQLVNEIIGFPRHLSQHVGGFVISSGPLYELVPVENAAMEDRTIIQWDKDDLESLELLKVDVLALGMLNAIRKCFQLIEKHHQRSLSIAEITRRQDDPHVYRMLQKADTVGVFQIESRAQMSMLPRLKPACYYDLVIQIAIVRPGPIQGDMVHPFLKRRNGEEPVSYPSEAVKSVLERTMGVPIFQEQVIKLAMVAAGFSGGEADQLRRAMASWKKNGDLAKFKPKLLNGMQERGYDLAFAERIFEQICGFGEYGFPESHSASFAVLAYCSAWLKYYYPAEFYTALLNSQPMGFYSPSQLVQDARRHGVEVLPICVNHSYYQHHLIQRPNGRLGVQLGFRLVKGFNEEGATRLVERRPKTGYHSIQEVKQILRSRRDIELLASANAFQILSGNRYNARWAAMDSLSDLPLFHHIEEPSVGYQVQPSEYESLIEDYASTGLSLNRHPITLLEEAGILPRFTRMKQLVDKEHKSLVTVAGVVTGRQSPGTAAGVTFFTLEDDTGNINVVVWSATARAQKQAYLTSKILMVKGILEREGEVIHVIAGKLIDCTHYLSNLQSKSRDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_CHLAB
Sequence: MSLKIVYFGTPQFAATVLADLLHHEVNVVAVVTRVDKPQKRSSQLIPSPVKTLALSKNIPLLQPEKVSDPQFVEQLRDFEADVFIVVAYGAILKQMVLDIPKYGCYNLHAGLLPAYRGAAPIQRCIMDGVVQSGNTVIRMDAGMDTGDIANVSFVPVGPDMTAGELAEALASQGGEILIKTLQQISDGTITHTPQEASKASIAPKLSKEEGFILWDHPAEKVYAQIRGVTPAPGAWTLYSYQGKPARRLVIRKASLSSSQGVYGHPGDILLSDQQELLVACAEGAICLKEIQPEGKGVMDSKSFLNGHSGHKLKLSLNLMS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RF1_CAMJE
Sequence: MLASKLDPFFKRFEELNSLLSSSDILNDISKMTTLSKEQKNLEPIVLKAKEYLKTLDNIEENKALLNDPELGELAKEELKTLEELKPKLEEEIKILLLPKDPNDERNIFLEIRAGTGGDEASLFVGDLVKAYARYAENRGYKLEIVSSSEGSVGGFKEIIMLVKGTGAYSRLKYEGGTHRVQRVPQTESQGRVHTSAITVAVMPEVDDIEIEINPNDLKVDVMRSSGHGGQSVNTTDSAVRITHIPTGIVVVNQDGKSQHKNKESAMKVLKARLYEMQESERLAKESEARKSQVGSGDRSERIRTYNFPQNRISDHRINLTLYRLDAIMQDGLFDEIIEPLITHHQAQALQEQNL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_NICTO
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ISPD_SYNY3
Sequence: MHLLIPAAGSGKRMGSGHNKLLLNVLGQPLLSWTVQAALASQSIEWIGIMGQPYDFPAFEALLTPLHSPKPVQLIVGGDTRQQSVFNGIQALPPGAKFVLIHDGARCLATPDLFDRCTEALQHCQGLIAAMPVKDTIKIVNADGWITDTPDRQGLWGAQTPQGFDVALLKACHDKGKQEGWEVTDDAALLEKCGQPVKIVPGEDTNLKITTPVDLAIAEFILGQRSAKSA
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: CCR8_HUMAN
Sequence: MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
What is the function of this protein?
Receptor for the chemokine CCL1/SCYA1/I-309.  May regulate monocyte chemotaxis and thymic cell line apoptosis.  Alternative coreceptor with CD4 for HIV-1 infection.
What are the official names of this protein?
C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MX1_HUMAN
Sequence: MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLIIQFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG
What is the function of this protein?
Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses.  Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid.  May also antagonize reoviridae and asfarviridae replication.  Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids.  Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress.  Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles.  Enhances ER stress-mediated cell death after influenza virus infection.  May regulate the calcium channel activity of TRPCs.
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, IFI-78K, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Binds preferentially to negatively charged phospholipids (PubMed:21900240). Colocalizes with CCHFV protein N in the perinuclear region (PubMed:15047845). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus. Note=Translocates into the nuclei of HSV-1 infected cells (PubMed:20603636).