PharMolix/UniProtQA huggingface dataset:
Protein: SYK2_ECO57
Sequence: MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK
What are the official names of this protein?
Lysine--tRNA ligase, heat inducible, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_THESQ
Sequence: MVVVGLGNPGPRYAFTRHNVGFLFLDFLKNKDWKTEKYFAWNKINLAGNEVALVKPLTYMNLSGLAMPHVLKFFSASLDDIIVVYDDVSLKLGKIRIRKKGSDGGHNGMKSIIQALGTQEIKRIRVGIGDKPEGMDLVDFVLGEFSDEEWIILNKVFEVMKEALEVILVEGIEKAMSIYNSLEVRV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y715_STAES
Sequence: MILGLALVPSKSFQDEVNAYRKRYDNHYAQIMPHITIKPQFEIDDHDFNLIKNEVKNRISSIKPVEVHATKASNFAPVSNVIYFKVAKTESLEQLFNQFNTEDFYGIAEHPFVPHFTIAQGLTSQEFEDIYGQVKLAGVDHREIIEELSLLQYSEEEDKWTIIETFTLG
What are the official names of this protein?
Putative phosphoesterase SE_0715.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: RNZ_STAAE
Sequence: MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: CH10_PROMP
Sequence: MAAVSLTVSTVKPLGDRIFIKVSESEEKTAGGILLPDSAKEKPQVGEVAQVGPGKLNDDGSRQTPEVSIGDKVLYSKYAGTDIKLGGDEYVLLSEKDILAVVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHTA_VIBCH
Sequence: MVKIIFVFFIFLSSFSYANDDKLYRADSRPPDEIKQSGGLMPRGQSEYFDRGTQMNINLYDHARGTQTGFVRHDDGYVSTSISLRSAHLVGQTILSGHSTYYIYVIATAPNMFNVNDVLGAYSPHPDEQEVSALGGIPYSQIYGWYRVHFGVLDEQLHRNRGYRDRYYSNLDIAPAADGYGLAGFPPEHRAWREEPWIHHAPPGCGNAPRSSMSNTCDEKTQSLGVKFLDEYQSKVKRQIFSGYQSDIDTHNRIKDEL
What is the function of this protein?
The A1 chain catalyzes the ADP-ribosylation of Gs alpha, a GTP-binding regulatory protein, to activate the adenylate cyclase.  This leads to an overproduction of cAMP and eventually to a hypersecretion of chloride and bicarbonate followed by water, resulting in the characteristic cholera stool.  The A2 chain tethers A1 to the pentameric ring.
What are the official names of this protein?
Cholera enterotoxin subunit A, Cholera enterotoxin, A chain.
What is the protein family that this protein belongs to?
Belongs to the enterotoxin A family.
Protein: RL10_MYCLE
Sequence: MARADKATAVANIAEQFKAATAALITEYRGLTVANLAELRRSLTGSASYAVAKNTLIKRAASEVGIEGLDELFAGPTAIAFVTGEPVDAAKAIKTFAKEHKALVIKGGYMDGHPMTVAEVERIADLESREVLLAKLAGAMKGTFAKAIGLFNAPTSQMARLTAALQEKKAFEPASAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: VSP3_LACMR
Sequence: IVGGDECNINEHRFLVALYDPDGFFC
What is the function of this protein?
Thrombin-like snake venom serine protease that cleaves alpha-chain of fibrinogen (FGA) releases only fibrinopeptide A.  Shows coagulant, esterase and amidase activities.
What are the official names of this protein?
Thrombin-like enzyme LmrSP-3, SVTLE, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGI_WOLSU
Sequence: MSKAIKILLPLLLFSLSLQAERIKDIANIVGVRDNQLIGYGLVVGLNGTGDKTTSKFTMQSIANMLESVNVKIDADDIKSKNVAAVMVTAKLPPFSRQGDKVDVLVSSIGDAKSLEGGTLILTPLTGVDGRIYATSQGAISIGGKNERGGGVNHPLAGMLYGGAIIEREIPLDLYSKTGATLSLKSSNFQNAARVQESLNQNFGTQVAIAIDPRTIKLQRPESMSMVEFLARVEEVEIDYNRENKIVIDERTGTVVAGVGVKVGPVVVTHGEITIKITPEMSADNGAMDMGEGIKLSLNTNTLSTSGQTPTVSSVARALQRMGATPKDVISILEAIKRSGAISADLEIL
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: MTR_MYCTU
Sequence: METYDIAIIGTGSGNSILDERYASKRAAICEQGTFGGTCLNVGCIPTKMFVYAAEVAKTIRGASRYGIDAHIDRVRWDDVVSRVFGRIDPIALSGEDYRRCAPNIDVYRTHTRFGPVQADGRYLLRTDAGEEFTAEQVVIAAGSRPVIPPAILASGVDYHTSDTVMRIAELPEHIVIVGSGFIAAEFAHVFSALGVRVTLVIRGSCLLRHCDDTICERFTRIASTKWELRTHRNVVDGQQRGSGVALRLDDGCTINADLLLVATGRVSNADLLDAEQAGVDVEDGRVIVDEYQRTSARGVFALGDVSSPYLLKHVANHEARVVQHNLLCDWEDTQSMIVTDHRYVPAAVFTDPQIAAVGLTENQAVAKGLDISVKIQDYGDVAYGWAMEDTSGIVKLITERGSGRLLGAHIMGYQASSLIQPLIQAMSFGLTAAEMARGQYWIHPALPEVVENALLGLR
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of mycothione (the oxidized disulfide form of mycothiol) to mycothiol.
What are the official names of this protein?
Mycothione reductase, Mycothiol-disulfide reductase, NADPH-dependent mycothione reductase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Protein: UQCC1_XENLA
Sequence: MGFTGPLKYNKWKIKIAALRMYTCCVERIDYDEFFEKCSLPDTLNSWFLVTQLHVWMCLVRMKQEGRAGKYMCRYIVHSMWEDVEQRGKVMGIDSVTLKNSMRSMTEIFYAAIFGYDEGIISDDRILAAALWRNLLNKQCDDPRKLELLVEYVRKQVQFLDTLDGEDLLLTGEVVWRPLVEKDAQSILKPSTPTYNDEGL
What is the function of this protein?
Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex).  May be involved in cytochrome b translation and/or stability.
What are the official names of this protein?
Ubiquinol-cytochrome-c reductase complex assembly factor 1, Basic FGF-repressed Zic-binding protein homolog, Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog, Zic3-binding protein.
What is the protein family that this protein belongs to?
Belongs to the CBP3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: PSA1_HALVD
Sequence: MQGQAQQQAYDRGITIFSPDGRLYQVEYAREAVKRGTASIGVRTPEGVVLAADKRSRSPLMEPTSVEKIHKADDHIGIASAGHVADARQLIDFARRQSQVNRLRYGEPIGIETLTKEVTDHIQQYTQVGGARPFGVALLIGGVENGTPRLYETDPSGTPYEWKAVSIGADRGDHQEHLEENFRDDLTLDEGIELALEAIASTSDEGTAPDGVDVATVSAETERFVELSNDEIESYLEANDLLATEDDEQTEE
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.  The H. volcanii alpha1-beta proteasome is able to cleave oligopeptides after Phe, Tyr and Trp, poorly after Glu but not after Arg.  Thus, displays chymotrypsin-like activity, low caspase-like activity but no trypsin-like activity.
What are the official names of this protein?
Proteasome subunit alpha 1, 20S proteasome alpha subunit 1, Proteasome core protein PsmA 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAP8_ORYSI
Sequence: MEHKETGCQQPEGPILCINNCGFFGSAATMNMCSKCHKEMIMKQEQAKLAASSIDSIVNGGDSGKEPIIAGHAEVAVAQVEVKTLVAQPAEIAGPSEGVTVNPKGREGPNRCSTCRKRVGLTGFNCRCGNLYCAMHRYSDKHDCQFDYRTAARDAIAKANPVVKAEKLDKI
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 8, OsSAP8, Stress-associated protein 3.
Protein: RBSR_PASMU
Sequence: MATMKDIARIAKVSTSTVSHVINNSRFVSDEIRDKVMHVVKELNYTPSALARSLKVKETKTIGLLVTATNNPFFTEVVSGVEQYCHQHHYNLILSNTEGDTERLRHNLQTLIQKQVDGLLLMCSDARIQIGKDLNVNLPFVVMDWWPTEEKADKIYENSEYGGYLATKQLIEKGHQHIAIITGNLKKSLAQNRLDGYKKALKEANIPLREDCIIESHFDFEGGKRGMEKVLALQPRPTAVFACSDSIAFGAYQTVWHQGLHIPQDISIIGYDNITLAEYMSPPLTTINQPKAELGKLAVETLLQRIKNPTAKHRTLLLEPQLVWRESVRQLYQEKRG
What is the function of this protein?
Transcriptional repressor for the ribose rbsDACBK operon.
What are the official names of this protein?
Ribose operon repressor.
Protein: RS18_NEIMB
Sequence: MARQSFKRRKFCRFTAEKIQEVDYKQVDLLKDFISENGKIIPARITGTKAFYQRQLAVAVKRARFLALLPYTDQHK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: XISC_NOSS1
Sequence: MSGQNQGNCEETYSTSTHEYANADSTDWFADMFADFEPQNTTDGSYRGTMAKIKATELQYQAVFEQKLVEANTNLKRERIRVSIKQTGNSLQLRATLPLKPGDGSLGKTKKQYDLSLGIPANLEGLKTAIEESYELGKLIARHTFEWNEKYLGIKSREKQEIKTIGELLDKFEEKYYQTRQKTITSQNTFPNYISVIKRNFPLTHLATKENFEEIINSVQGNKKNELIAVTSVFIKTFNLGFQLDVKRDNVTPAHREIPEDDKIIYSFDLFEKFALNRKNTNISDEIDTWEMWRWVYGMLATFGLRPRELFVQPDINWWMSPQNLDHTWKVNKNTKTGYREVIPFVPEWIELFDLKNPKPLKILEKKVTKIASVQNINWMRRDISRWFRKVGIEFQPYDLRHACAIRAHLQGIPIKAAADNLGHTVDEHTKTYQRWFGIENRKKAFGEVISQKSLIELQKNEILALRMENERLRLEVEKLKFSTTKNPEDCEQLYHQG
What is the function of this protein?
Essential for DNA excision.  Site specific recombinase necessary for the excision of the 10. 5 kb hupL element during heterocyst differentiation.
What are the official names of this protein?
Excisase C, HupL element site-specific recombinase.
What is the protein family that this protein belongs to?
Belongs to the XisA/XisC recombinase family.
Protein: LSAMP_HUMAN
Sequence: MVRRVQPDRKQLPLVLLRLLCLLPTGLPVRSVDFNRGTDNITVRQGDTAILRCVVEDKNSKVAWLNRSGIIFAGHDKWSLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPTGREFEGEEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFRPGSVRGINGSISLAVPLWLLAASLLCLLSKC
What is the function of this protein?
Mediates selective neuronal growth and axon targeting.  Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system.  Essential for normal growth of the hippocampal mossy fiber projection (By similarity).
What are the official names of this protein?
Limbic system-associated membrane protein, LSAMP, IgLON family member 3.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IgLON family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: ATG12_HUMAN
Sequence: MAEEPQSVLQLPTSIAAGGEGLTDVSPETTTPEPPSSAAVSPGTEEPAGDTKKKIDILLKAVGDTPIMKTKKWAVERTRTIQGLIDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG
What is the function of this protein?
(Microbial infection) May act as a proviral factor.  In association with ATG5, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection (PubMed:17709747).  Required for the translation of incoming hepatitis C virus (HCV) RNA and, thereby, for the initiation of HCV replication, but not required once infection is established (PubMed:19666601).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=TECPR1 recruits the ATG12- ATG5 conjugate to the autolysosomal membrane.
Protein: TATA_AZOVD
Sequence: MGIFDWKHWLIILIVVVLVFGTKRLKTLGSDIGEAIKGFRKAVNTEEGENRPAEPQTGTSAGDTLNKTQTIEGQAQKVDTPVRKD
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AAT2_PSEMZ
Sequence: VATVQGLSGTGSLRNLGLYAERQIGMFSFTGLNK
What is the function of this protein?
Important for the metabolism of amino acids and Krebs-cycle related organic acids.  In plants, it is involved in nitrogen metabolism and in aspects of carbon and energy metabolism (By similarity).
What are the official names of this protein?
Aspartate aminotransferase 2, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: PBN1_GIBZE
Sequence: MRERVTFIHNDYSLDPEALDNQDAGLLGPQIETVRQDKLTIPFGELPSELTDILQEYEALHIRWASPVKSETMDPFTSRISPGLHVYATPVLPSSCNPTKLCSWLQRFGPLDCSKPEAFTEFQQSTSTSPSFSFYEALEDLHSFITTSSQEFCPELDSVCNARLRSLLTASGLDLSFDKAANALVVSALWPLRPQTVAVPASSARRVEVGIFINDRSQPNMKENELGVAGVLSVLGDQKKPSPTIFTFPARHRRDGSVFTSKFLTPTGLHPTLQLSFNSNKLPSADGECAPYAFLTLPKTIFADRYQLGDELFLASKNLTALRYTTLPVDLEAPAYTTETWGSSILLGLAPPDPGTEKPWSVEIPLHLRYLKPSATGQVEIEIPYPAVFWACSSEEGTLESPFDRLHVGYDYLFPRDTVFWHANPQPENGSRLMNRVTVPVLDDDGVGSIRSGTAIAVAIGFAWVMWKLVSVMLKSDRAPAGVTKETKQKKSH
What is the function of this protein?
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum.  Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.  Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
What are the official names of this protein?
Protein PBN1.
What is the protein family that this protein belongs to?
Belongs to the PIGX family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: F16PA_SULSY
Sequence: MAKIGMDLNSFILEQERLYPNATGSLSRALVAIESATKVIASHVRMAGLADILGMAGKKNIQGEEVQKLDELSNNLLIQYLSQSGEFFALASEELDEPIFPEEGKDAKYVIAFDPLDGSSNIDVNISIGTIFSIHRRVNSDVSDFLQEGYKQVAAGYVIYGSSTMLVLSTGNGVNGFTLDPAVGMYLLSHPNMKIPEKGKIYSINESNDKKWIDAGLKEYIESLKDEGYTSRYIGSMVADVHRTLIKGGIFAYPADVKNKNGKLRLLYEASPMAFLTVQAGGIATTGKEDILNIKPTDIHQRVPVFLGGKYEMEKLKSMLKNG
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRYP_PHACE
Sequence: MIRFTLALAVIGVTFAASTPQIETNPNLEIIGGHDANIIDYPWQISFQHRLHHFCGGFLISDTWVVTAAHCIYEGYSDTENLNIRVGSSEWSAKGKLHDVKRYITHPQYNITTMDNDIALLELALPVDLNQSVRPAKLPVAGQEIPDNAQLTITGWGATYVGGYNEYTLQVVTIPTVNINVCQSAITNDTITNNMFCAGLIGVGGKDSCSGDSGGPAVIDGQVVGIVSWGYSCADPKYPGIYTKVSAFRDWINEETEI
What are the official names of this protein?
Trypsin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROFO_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-1, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: H33_LODEL
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKSAPVSGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKSDLRFQSSAIGALQEAVEAYLVGLFEDTNLCAIHAKRVTIQKKDIQLARRLRGERS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y1797_COREF
Sequence: MSDTAELTTDPTPDLTKGDTITVEVTRPAHGGEGIAHHGGRVIFVRGGFPGDDVDVEITQVKKRFARGFVVQVNVASPHRVDSRCPAAAAGAGCCDYAELSPEAELEIKSRVLTDQLQRIGGLADIPTPELFELEPSQGWRTRVRLGVDASGRAGFRKLRSNDLVTDVACSQVVPELIDGLVGPGARTFTPDSEVIAAIDDRGVRTVVEVRKAPRGRRAETILHVLEGDGSVEQTVGDHTWTFPVSGFWQAHTKAPGAYSAFIGEVLDGAELVDVDKRGPVAWDLYGGVGLFVPVINRALGAHVHSVELSEGSAEAGDDALAGLPVTFHAGRVESVTSQLPKPHVVVLDPPRTGAGSDVVATIAGAKPQLVVHIGCDPATFARDVADWSAGGYTLDRLAVFNAFPATHHYETIGVFTRKSA
What are the official names of this protein?
Uncharacterized RNA methyltransferase CE1797.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: RIMP_FRATH
Sequence: MLLDDLYEIVEPITADLGYILWGIEVVGSGKLTIRIFIDHENGVSVDDCQIVSKEISAVFDVEDPVSGKYILEVSSPGMNRQIFNIIQAQALVGFNVKAVTLAPVGSQTKFKGVLERVEGNNVILNLEDGKEISFDFDELKKLRVSPDFS
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_PSEF5
Sequence: MKISREAYADMFGPTVGDKVRLADTELWIEVEKDFTTYGEEVKFGGGKVIRDGMGQSQLLAAEVVDTLITNALIIDHWGIVKADVGLKDGRIAAIGKAGNPDIQPDVNIAIGASTEVIAGEGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTCTSGPWHMARMLQAADAFAMNIGFTGKGNASLPEPLIEQVKAGAIGLKLHEDWGSTPASIDNCLSVADEYDVQVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGLANVLPSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVVTRTWQTADKMHKQRGPLPGDGPGNSNFRVKRYIAKYTINPAITHGISHEVGSVEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASFGGSRHATSLTFISQAALEAGVPEQLGLKKRIAVVKGCRNVQKTDLIHNDYLPDIEVDPQTYQVKADGVLLWCEPADVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIM20_RAT
Sequence: MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK
What is the function of this protein?
Peptide involved in a broad spectrum of regulatory functions (PubMed:27440717, PubMed:28844870, PubMed:29364701, PubMed:28965207, PubMed:30609107).  Is a ligand for GPR173 (PubMed:27440717).  As part of the reproductive cycle, it regulates gonadotropin-releasing hormone (GnRH) signaling in the hypothalamus and pituitary gland which augments the release of luteinizing hormone (PubMed:22963497, PubMed:27440717).  More specifically, it regulates the expression of transcription factors CEBPB and POU2F1/OCT1 through the cAMP-PKA signaling pathway, which subsequently regulate the expression of GNRHR and KISS1 (By similarity).  Plays a protective role in memory retention through activation of GNRHR (By similarity).  Regulates the secretion of AVP by hypothalamic neurons (PubMed:29364701).  Plays a role in the transduction of the itch sensation (By similarity).  Induces anxiolytic effects, reducing behavior associated with anxiety (By similarity).  Regulates food intake as well as satiation and satiety by increasing NUCB2 expression in neurons (PubMed:28844870, PubMed:30930149).  In the ovary, it regulates follicular growth by stimulating granulosa cell proliferation by increasing the expression of GPR173, CREB1, CYP19A1, KITLG, FSHR, and LHCGR (By similarity).  It also increases the production of estradiol (E2) (By similarity).  In the heart, it regulates contractility and relaxation by activating the AKT1-NOS3 and MAPK1-MAPK3 signaling pathways (PubMed:28965207).  It also plays a cardioprotective role during ischemia, where it activates the SAFE and RISK pathways (PubMed:28965207).  Stimulates the proliferation and differentiation of preadipocytes (PubMed:30251651).  In pancreatic islet cells, it induces proliferation of islet cells as well as the production of INS1 and INS2 through activation of the MAPK1-MAPK3 signaling pathways (PubMed:31422055).
What are the official names of this protein?
Small integral membrane protein 20, Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 7 kDa, MITRAC7.
What are the subcellular locations of this protein?
[Small integral membrane protein 20]: Mitochondrion inner membrane; Single- pass membrane protein. SUBCELLULAR LOCATION: [Phoenixin-14]: Secreted. SUBCELLULAR LOCATION: [Phoenixin-20]: Secreted.
Protein: PANB_SHEFN
Sequence: MSKVTSSTLIKFKQEGKKFTALTAYDASFAGAFDSEGVDVLLVGDSLGMVLQGHNDTLPVTIADIAYHTACVKRGVARALLIADMPFMSYSTPEQTMNNAAILMQAGASMVKLEGGHWLLESVKMLTERGIPVCAHLGLTPQSVNVFGGFKVQGRDADNAQRILDEAKALQAAGAQLLVVECIPAPLAKAITEALTIPVIGIGAGADTDGQILVMHDVLGISSGYIPRFSKNYLKQTGEIRSAIRAYIDEVANGTFPAEEHTFN
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.