PharMolix/UniProtQA huggingface dataset:
Protein: ES8L1_MOUSE
Sequence: MSTTTGPEAAPKPSAKSIYEQRKRYSTVVMADVSQYHVNHLVTFCLGEEDGVHTVEDASRKLAVMDSQGRVWAQEMLLRVSPSQVTLLDPVSKEELESYPLDAIVRCDAVMPRGRSRSLLLLVCQEPERAQPDVHFFQGLLLGAELIREDIQGALQNYRSGRGERRAAALRATQEELRRGASPAAETPPLQRRPSVRLVINTVEPSAVRGRPQVESIPETEEARKPDQARTTSSADPTSPDLGPRGPELAGLQAERDVDILNHVFDDVESFVSRLQKSAEATRVLEHRERGRRTRRRAAGEGLLTLRAKPPTEAEYTDVLQKIKYAFSLLARLRGNIANPSSPELLHFLFGPLQMIVNTSGGPEFAKSVRRPHLTLEAVTLLRDNVTPGENELWTSLGDSWTCPGVELPPEEGSPYSPEFYNGWEPPATDPQGRPWEDPVEKQLQHEKRRRQQSAPQVAVNGQQDPELETESQLEEKARKWVLCNYDFQARNGSELSVKHRDVLEVLDDRRKWWKVRDHQGQEGYVPYNILTPHPGPQVHRSQSPARHLETSTPPPPPAPAPAPTQVRPQWDSCDSLNSLDPSEKEKFSQMLCVNEELQSRLAQGRSGPSRVTPGPRAQEPQLSPRSEASVVRAWLQTKGFSSGTVEALGVLTGAQLFSLQKEELRAVCPEEGARVYSQVTVQRALLEDREKVSELEAVMEKQKKKVEGETKTEVI
What is the function of this protein?
Stimulates guanine exchange activity of SOS1.  May play a role in membrane ruffling and remodeling of the actin cytoskeleton (By similarity).
What are the official names of this protein?
Epidermal growth factor receptor kinase substrate 8-like protein 1, EPS8-like protein 1, Epidermal growth factor receptor pathway substrate 8-related protein 1, EPS8-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the EPS8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_SHIB3
Sequence: MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDYYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPRQPVQQPPEAQVPPQHAPRPAQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: TSAD_HAHCH
Sequence: MLVLGIETSCDETGIALYDGERGLLAHTLYSQIKLHADYGGVVPELASRDHVRKVIPLIEEVLNQAGVGKSDIDAIAYTAGPGLVGALMVGGAIASALAYALGIPTIGVHHMEGHLLAPMLEENPPEFPFVALLVSGGHTQLVRVDGVGEYELLGESVDDAAGEAFDKVAKMLGLDYPGGPQVAKLAEEGNLQRFKFPRPMTDRPGLDFSFSGLKTFTLNTLQEAEASGGVDDNLRADVAACFQEAVVETMVIKCRRALRQTGLKRLIMAGGVSANRRLREKLQQMVKGEKALVYYARPEFCTDNGAMIAYAGHQRLAVGQRGDLSVLATPRWPLVELPSIKG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LR2BP_RAT
Sequence: MKLTSEKLPKNPFSLSQYAAKQQTFFQWKKEKPDYYRHANLVDTALQFLKERIRKGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQAIYQLGVMYYDGLGTVADAEKGVGYMKKILDSSCPQTMHLKFAAAYNLGRAYFEGKGVKRSDEEAERLWLYAADNGNPKASVKAQSILGLFYSMKEPKDLEKAFFWHSEACGNGNLESQGALGLMYLYGQGIRQDTDAALHCLREAAERGNVYAQGILVEYYYKMKFFTKCVSFSKRIADYDEVHDIPMIAHVTDCLPEFISKGMAMASFYYARCLQLGLGITKDEASAKHYYSKACRLNPTLADELHSLLIHQRI
What is the function of this protein?
May act as an adapter that regulates LRP2 function.
What are the official names of this protein?
LRP2-binding protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Detected in a vesicular staining pattern close to the plasma membrane and throughout the cytoplasm.
Protein: PRTB_DICCH
Sequence: MQQNEKASLNTSAAAAKAGSYTGYADVYDFWYYHQRGDGLTVNGKPSYTTDKAVSEGLTRPHTTWNGDNVFGKAANLTYSFLNTFSSTPNGHTGPVKFTPVQMQQAKLSLQSWADAANLTFTEVSPNQKANITFANYTRNADGSLNTDTQAYAAYPGTHPVSGSAWFNYNQSSIRNPDTDEYGRHSFTHEIGHALGLSHPAEYNAGEGDISYKNSAAYAEDSRQFSIMSYWEVENTGGDFKGHYSAGPLMDDIAAIQKLYGANMTTRTGDTVYGFNSNTDRDFYTATNSSKALVFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILIGNGADNILQGGAGDDVLYGSTGADTLTGGAGRDIFVYGSGQDSTVSAYDWITDFQTGIDKIDLSAFRNEGQLSFVQDQFTGKGQEVMLQWDAANSTTNLWLHEAGHSSVDFLVRIVGQTAQSDIIV
What are the official names of this protein?
Serralysin B, Secreted protease B, ProB.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10B family.
What are the subcellular locations of this protein?
Secreted.
Protein: AATC_YEAST
Sequence: MSATLFNNIELLPPDALFGIKQRYGQDQRATKVDLGIGAYRDDNGKPWVLPSVKAAEKLIHNDSSYNHEYLGITGLPSLTSNAAKIIFGTQSDAFQEDRVISVQSLSGTGALHISAKFFSKFFPDKLVYLSKPTWANHMAIFENQGLKTATYPYWANETKSLDLNGFLNAIQKAPEGSIFVLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFATGDLDKDAYAVRLGVEKLSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQNKTIKPAVTSQLAKIIRSEVSNPPAYGAKIVAKLLETPELTEQWHKDMVTMSSRITKMRHALRDHLVKLGTPGNWDHIVNQCGMFSFTGLTPQMVKRLEETHAVYLVASGRASIAGLNQGNVEYVAKAIDEVVRFYTIEAKL
What is the function of this protein?
Plays a key role in amino acid metabolism.
What are the official names of this protein?
Aspartate aminotransferase, cytoplasmic, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome. Note=Targeted to peroxisomes in cells grown in oleate.
Protein: TRMD_MYCPU
Sequence: MLKINFLTIFPKYFDCFLKESIIGKAIERKKISINVIDFREFSENKHKKVDDSVYGGGQGMLLQVQPIAKALKTLKGLKILVSPQGKLFNQEIAKEIVKNHSEITFVSGRYEGFDERILNYIDIELSIGDYILTGGELPSMVMADSIIRLWEDVIKKESYENESFENNLLDYPQYTRPRVFEGFEVPEILLNGNHKEIEKWRKQKQIEKTKINRPDLYERFKNEK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEC1_SOLFI
Sequence: GRYTVQNQWGGSSAPWNDAGLWLLGSRANQNVMDVSVTSSDGGATLTGTMTYSGEGPIGFKGTRRGDSNNYDVENQWGGSSAPWHAGGTFVIGSRSGQGVVAVDVNSSDGGKTLTGTMTYANEGPIGFKGTQSGGDSYNVENQWGGSSAPWNKAGAWALGDRDGQGVIGVDVTSSDGGKTLTGTMQYQNEGPIGFKGTSTGGSNYKVENQWGGSSAPWNPAGNWLIGDRHNQNIVAVKVTSSDNGKTLGGTCTYEREGPIGFKGTAI
What is the function of this protein?
Lectin specific for high mannose N-glycans, recognizes the branched moiety of these glycans.  Does not recognize other types of N-glycans or monosaccharides.
What are the official names of this protein?
Lectin SfL-1.
What is the protein family that this protein belongs to?
Belongs to the bacterial lectin family.
Protein: SUA5_PYRAB
Sequence: MTIIINVRERIEEWKIRIAAGFIREGKLVAFPTETVYGLGANALDENAVKRIFEAKGRPADNPLIIHIASFEQLEVLAKEIPEEAEMLAKRFWPGPLTLVLPKSEVVPRVITGGLDTVAVRMPAHEIALKLIELSERPIAAPSANISGKPSPTSAHHVAEDFYGKIECIIDGGETRIGVESTVIDLTEWPPVLLRPGGLPLEEIEKVIGEIRIHPAVYGKSVDTAKAPGMKYRHYAPSAEVIVVEGPRDKVRRKIEELIAKFKEEGKKVGVIGSGSYDADEVFYLGDTVEEIARNLFKALRHMDRTGVDVILAEGVEEKGLGLAVMNRLRKASGYRIIKV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Likely catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.  Does not bind tRNA.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Sua5, tRNA threonylcarbamoyladenosine biosynthesis protein Sua5.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO102_YEAST
Sequence: MQARRQTLPQFIKCKQTKCKIKLATINSAKALFLEMPGKLLHNCNRKLINRTNCPTQIMNPAKNALNGKLSRIKIMNVHWITPNNTKKKQNVSISFSLGYFSIWAKYALLEVLKVS
What are the official names of this protein?
Putative uncharacterized protein YOR102W.
Protein: LCL3_CLAL4
Sequence: MSDEPLSSSEESPSVSVLHPKVLLLSAGFTGAAAASYFLYGRYVRRVKTYLDLTPAILDGQRKLYGKVTRVGDGDNFRFFHTPGGVLLGWGWLRKIPDTRSGLKDQTLMVRLCGVDAPERSHFGKPAQPFSEEALQWLQSYVGGRSVTITPYSIDQYKRVVARAQVWRWTGKRDVSAEMLRNGLGVVYEANSGAEFGENEGWYRRLEEKAKRRRRGMWSLGSKLVTPGNFKRQ
What are the official names of this protein?
Probable endonuclease LCL3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: CHFR_MOUSE
Sequence: MELHGEEQPPPPQEPWGRLLRLGAEEDEPQILLWKREWTIGRRRGCDLSFPSNKLVSGDHCKLTVDEISGEVTLEDTSTNGTVINKLQVVKKQTYPLQSGDIIYLVYRKNEPEHNVAYLYESLSGKQSLTQDSLEANKENMFHVTKDCSGPGQGDDPQVPLLSPMAQTCLEEPQPSTSTSDLLPTASTSSTEPELTSAGQKHSSSSGPGNTSISPKGRSSLVANGELSSLSPVFQDKEASFSLLESKDHEELEPAKKKMKGDGELDTNLQLLVSGQRGNAQTSSEDVKDASVKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYSGWMERSSLCPTCRCPVERICKNHILNNLVEAYLIQHPDKSRSEEDVRSMDARNKITQDMLQPKVRRSFSDEEGSSEDLLELSDVDSESSDISQPYIVCRQCPEYRRQAVQSLPCPVPESELGATLALGGEAPSTSASLPTAAPDYMCPLQGSHAICTCCFQPMPDRRAEREQDPRVAPQQCAVCLQPFCHLYWGCTRTGCFGCLAPFCELNLGDKCLDGVLNNNNYESDILKNYLATRGLTWKSVLTESLLALQRGVFMLSDYRITGNTVLCYCCGLRSFRELTYQYRQNIPASELPVTVTSRPDCYWGRNCRTQVKAHHAMKFNHICEQTRFKN
What is the function of this protein?
E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons.  Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus.  Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome.  Promotes the ubiquitination and subsequent degradation of AURKA and PLK1.  Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation.  May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer.  Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase CHFR, Checkpoint with forkhead and RING finger domains protein, RING-type E3 ubiquitin transferase CHFR.
What is the protein family that this protein belongs to?
Belongs to the CHFR family.
What are the subcellular locations of this protein?
Nucleus, PML body.
Protein: RLME_BURO1
Sequence: MAKNRFNQHWLHDHINDPYVKMAQREGYRARAAYKLKEIDEQDKLIRPGQVIVDLGATPGSWSQYARNKLAQGKKRDAEREGGIDGTIVALDILPMEPIADVHFLQGDFREDDVLHQLEEVLEGRAVDLVISDMAPNLSGVASADAARIEHLCDLALEFAQNHLKPDGALLVKCFHGSGYSQIVEKFKQQFKVVAPRKPKASRDKSSETFILGRQLKHPR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
Protein: DLG1_MOUSE
Sequence: MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCVDHSKQCEPVQPVTTWEIASLPSTAVTSETLPGSLSPPVEKYRYQDEEVLPPEHISPQVTNEVLGPELVHVSEKNLSEIENVHGFVSHSHISPIKPTEAVPPSSPIVPVTPALPVPAESTVVLPSAPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVKRRKPASEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYINDGYAPPDITNSSSQSVDNHVSPSSCLGQTPTSPARYSPISKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFRFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPAKEKL
What is the function of this protein?
Essential multidomain scaffolding protein required for normal development.  Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells.  Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels (By similarity).  Functional regulator of Kv1. 5 channel (By similarity).  May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation.  During long-term depression in hippocampal neurons, it recruits ADAM10 to the plasma membrane (PubMed:23676497).
What are the official names of this protein?
Disks large homolog 1, Embryo-dlg/synapse-associated protein 97, E-dlg/SAP97, Synapse-associated protein 97, SAP-97, SAP97.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Basolateral cell membrane. Endoplasmic reticulum membrane. Postsynaptic density. Synapse. Cell membrane, sarcolemma. Cell junction. Cytoplasm. Apical cell membrane. Note=Colocalizes with EPB41 at regions of intercellular contacts. Basolateral in epithelial cells. May also associate with endoplasmic reticulum membranes. Mainly found in neurons soma, moderately found at postsynaptic densities.
Protein: LMT4_LOCMI
Sequence: RLHQNGMPFSPRL
What is the function of this protein?
Potent mediator of visceral muscle contractile activity (myotropic activity).  LOM-MT IV seems to be a more potent muscle stimulator than LOM-MT I, II and III.
What are the official names of this protein?
Locustamyotropin-4, Lom-MT-4.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_LACLA
Sequence: MLLNGIVAAVITMIITIIGIPRFIMFFHKKKLGGQPTLEDVKQHASKAGTPTMGGFVFVVVSLVVSLIAALVFGKFSPAFITAWWVFAMYAVIGFLDDFLKVFKQINEGLTAKQKMLAQILIGIVSYFIYSHGEKSHIIHLLSWEFNIGIFFSIFIIIWLVGWSNAVNLTDGIDGLASITVAISLTAYAVIAVAHQQYDVLLIILSVIGGLLGFFVFNHKPAKIFMGDVGSLALGGFLAIVSILLHAEWTLLLIGAVYVIETLSVMLQVAYFKKTGGKRIFRMTPIHHHFELGGFSGKAAGWSEWKIDIVFWLFTAVLSVIALCIYFAF
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRDR_CORA7
Sequence: MYCPFCHNEQSRVIDSRVIDSGTSIRRRRECAACKGRFTTIEKAVLSVVKRNGLAEPFSRDKLIRGVKRACQGRDVSDDALKKLAQEVEETVRSHGSSQVNANDIGLAILEPLRDLDEVAYLRFASVYKSFESADDFESEIRLMRRRDRDSF
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ACCD6_MYCTU
Sequence: MTIMAPEAVGESLDPRDPLLRLSNFFDDGSVELLHERDRSGVLAAAGTVNGVRTIAFCTDGTVMGGAMGVEGCTHIVNAYDTAIEDQSPIVGIWHSGGARLAEGVRALHAVGQVFEAMIRASGYIPQISVVVGFAAGGAAYGPALTDVVVMAPESRVFVTGPDVVRSVTGEDVDMASLGGPETHHKKSGVCHIVADDELDAYDRGRRLVGLFCQQGHFDRSKAEAGDTDIHALLPESSRRAYDVRPIVTAILDADTPFDEFQANWAPSMVVGLGRLSGRTVGVLANNPLRLGGCLNSESAEKAARFVRLCDAFGIPLVVVVDVPGYLPGVDQEWGGVVRRGAKLLHAFGECTVPRVTLVTRKTYGGAYIAMNSRSLNATKVFAWPDAEVAVMGAKAAVGILHKKKLAAAPEHEREALHDQLAAEHERIAGGVDSALDIGVVDEKIDPAHTRSKLTEALAQAPARRGRHKNIPL
What is the function of this protein?
Component of a biotin-dependent acyl-CoA carboxylase complex.  This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate (PubMed:17114269).  When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA, with a preference for acetyl-CoA (PubMed:17114269).
What are the official names of this protein?
Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase beta6 subunit, Acetyl-CoA carboxylase, ACC, Propionyl-CoA carboxylase, PCC.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
Protein: RPOZ_NOVAD
Sequence: MARVTVEDCVDKVPNRFDLVLLAAERARAISGGAELTVDRDRDKNPVVALREIAEETVRPAVLKENLIQSLQRVLPDDDDEVDEIGSLSQSAEALRITAAAPVRNTSLGADYDG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: Y831_STRT2
Sequence: MKTKIINLVVVTGMSGAGKTVAIQSFEDIGYFTIDNIPPSLVPKVIELLKHSEETDKIALVVDMRSRVFFDEINDILDQLESNEELNFKILFLDATDGELVSRYKETRRSHPLAADGRVLDGIKLERELLSPLKSLSQNVVDTTKLTPRQLRKAISEQFSSKQDQSSFRIEVLSFGFKYGLPLDADLVFDVRFLPNPYYDPTLRNLTGLDKEVYDFVMTHKESEDFYKNLNHLIKPILPGYQKEGKSVLTIAVGCTGGQHRSVAFAHRLAQDLKNDWTVNETHRDKDRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein stu0831.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RAS2_MAGO7
Sequence: MAQSKFLREYKLVVVGGGGVGKSCLTIQLIQSHFVDEYDPTIEDSYRKQCVIDDEVALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSITSRQSFEEITTFQQQILRVKDKDYFPMVVVGNKCDLEGEREVTRQEGEALARSFNCKFIETSAKSRINVDKAFYDIVREIRRYNREMQGYSTGSGGSNAGGPSNKMEVNDSDAEAGCCSKCVLM
What is the function of this protein?
Modulates the activity of the adenylate cyclase catalytic subunit and therefore affects the biosynthesis of cyclic-AMP (By similarity).  Plays a role in both surface attachment and surface recognition of appressoria, a highly specialized infection structure for plant penetration.  Regulates appressorium formation by coordinated regulation of cAMP signaling and Pmk1 MAPK pathways (PubMed:24835254).
What are the official names of this protein?
Ras-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RPOA_BURPS
Sequence: MQTSLLKPKIIAVESLGENHAKVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTLDGVQEDVVNLLLNLKGVVFKLHNRDEVTVTLRKEGEGVVTAGDIELAHDCEVINPNHVIAHLSKGGKLDVQIKVEKGRGYVPGNVRRYGDETAKIIGRIVLDASFSPVRRVSYTVESARVEQRTDLDKLVMNIETSGVITPEEAIRQSARILVDQLSVFAALEGTETAAEAPSRAPQIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: CHBG_ESCF3
Sequence: MERLLIVNADDFGLSKGQNYGIIEACRNGVVTSTTALVNGEAIDHAAQLSRGAPGLAVGMHFVLTMGKPLTEMPGLTREGMLGKWIWQMAEEGALPLEEISLELASQYQRFIELFGRKPTHIDSHHHVHMFPQIFPIVASFAAEQGIALRIDRQAVFNDSDLPGELRSSQGFSSAFYGEEISNALFLKVLDDSSHRGERSLEVMCHPAFIDNTIRQSAYCFPRLTELDVLTSASLKYAIAERGYRLGSYLDV
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHO_ECO8A
Sequence: MRIAKIGVIALFLFMAFGGIGGVMLAGYTFILRAG
What are the official names of this protein?
UPF0387 membrane protein YohO.
What is the protein family that this protein belongs to?
Belongs to the UPF0387 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TL19_SPIOL
Sequence: DSPTPNTYNIYYGTAASAXN
What are the official names of this protein?
Thylakoid lumenal 18.4 kDa protein, P18.4.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: T2R10_GORGO
Sequence: MLRVVEGIFIFVVISEXVFGVLGNGFIGLVNCIDCAKNKLSTIGFILTGLAISRIFLIWIIITDGFIQIFSPDIYASGNLIEYISYFWVIGNQSSMWFATSLSIFYFLKIANFSNYIFLWLKSRTNMVLPFMIVFLLISSLLNFAHIAKILNDYKMKNDTVWDLNMYKSEYFIKQILLNLGVIFFFTLSLITCVFLIISLWRHNRQMQSNVTGLRDSNTEAHVKAMKVLISFXILFILYFIGMAIEISCFTVRENKLLLMFGMTTTAIYPWGHSFILILGNSKLKQASLRVLQQLKCCEKRKNLRVT
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 10, T2R10.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TSAC_AERS4
Sequence: MSTEFEQAVAALHGEGVIAYATEAVFGLGCDPDSELAVQRLLAIKQRPVEKGLILIAADLVQLQDYIDLSQLSGEQLARVEASWPGPFTWIMPARATTPTWLTGQFDTLAVRVTAHPQVQALCRAFGKPLVSTSANLTGEEPARRVTDIGELLASKLAYILPGEVGGQANPSEIKDARTGAVIRPS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.