PharMolix/UniProtQA huggingface dataset:
Protein: MUTL_ACICJ
Sequence: MPIRRLDPTTINRIAAGEVIERPAAAVKELVENALDAGARRIGVTIEGGGIGRIEVTDDGHGIPEAELPLAIERHATSKLTDEALVRIATLGFRGEALPSIGAAGRLTVTSRPAGQDSAARIVVDGGAVREVEPVAGPVGTCVTVEDLFHATPARRKFLRSAGSEAGSCADAVRHLALAAPAVGFSLTIDGAASFDLPPQDRRERVAAIYGRADAEKLLEIEAVREEVALRGFISPASLTRAAARHQHMVVNGRPVRDPLLRMALRLAYRERIPAGRHPLAALWLEIPAEMLDVNVHPAKAELRFATPDAVRSLMIGAVQRALATPADLAAAPSVSMPRTSWAASSPMPRYPQAESRAARGFAEAELRGLDLPPARVAPEVLPESRPDYPLGTPIAQVFDTYILAQSGDGTLVLVDQHAAHERLTEIRLRAERDSGAIPAQALLAPSVVELPAEDIARLLGAAERLAGLGLEIEAFGPGAVLVRAVPAALAKADPAALARDVADTLAESGTAMALEAKLDAVLIRMACHRSVRAGRRLAFAEMEALLRAMETTPLAQTCPHGRPTVLRLSRGDLERMFGRAG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PIG16_CLAP2
Sequence: MSPPAEIQADTLKRFIAGWGGWTMESFFATLSDDFTQKPLPLSCGEPARGREQLYPLLSSLMTMMTNFKLTIHNTIHDPSNKAAVVYAVADGDTPFGPYHNEQAVFIWFNSKGDKVDRIEELFDTAFMAEFKPKFKKWALENPGAAAGRPPPANTST
What is the function of this protein?
Monooxygenase; part of the ergochrome gene cluster responsible for the typical purple-black color of the ergot sclerotia (Probable).  The ergochrome gene cluster produces several ergot pigments including the yellow ergochrome secalonic acid and its derivatives, as well as the red anthraquinones endocrocin and clavorubin (PubMed:28955461).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) CPUR_05437 (By similarity).  The atrochrysone carboxyl ACP thioesterase CPUR_05436 then breaks the thioester bond and releases the atrochrysone carboxylic acid from CPUR_05437 (By similarity).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (By similarity).  The next step is performed by the anthrone oxygenase CPUR_05434 that catalyzes the oxidation of emodinanthrone to emodin (By similarity).  Emodin is further modified to yield monodictyphenone via several steps involving CPUR_05427, CPUR_05428, CPUR_05429 and CPUR_05430 (By similarity).  The short chain dehydrogenase/reductase CPUR_05418 then catalyzes the C-5 ketoreduction to give the xanthone skeleton of the monomeric units (PubMed:32105084).  Ergochromes formation requires further dimerization steps of different xanthone units, probably catalyzed by the cytochrome P450 monooxygenase CPUR_05419 (PubMed:28955461).  CPUR_05425, CPUR_05426 and CPUR_05431 are unique to Claviceps, thus it is likely that they are involved in further modification of xanthone units or in their dimerization (PubMed:28955461).  The yellow ergochromes and the red anthraquinone pigments endocrocin and clavorubin are products from the same PKS derived precursors and the latter are likely shunt products in the pathway of xanthone biosynthesis (PubMed:28955461).  It is proposed that atrochrysone carboxylic acid released from the PKS CPUR_05437 can also be converted to endocrocin anthrone which is further oxidized into endocrocin by CPUR_05435 (By similarity).  Endocrocin could be then modified to clavorubin, possibly by CPUR_05423 and CPUR_05431 (PubMed:28955461).  Clavorubin is the principal anthraquinone metabolite produced by the cluster with a much higher yield compared to endocrocin (PubMed:28955461).
What are the official names of this protein?
Monooxygenase CPUR_05417, Ergochrome biosynthesis cluster protein CPUR_05417.
What is the protein family that this protein belongs to?
Belongs to the avfA family.
Protein: ISPG_PSEPG
Sequence: MHGESPIKRRESRKIWVGNVPVGGDAPIAVQSMTNTDTNDVAATVAQIQRLVDAGVDIVRVSVPDMDAAEAFGKIKQLVSVPLVADIHFDYKIALRVAELGVDCLRINPGNIGREDRVRAVVDAARDRGIPIRIGVNAGSLEKDLQKKYGEPTPAALVESALRHVEHLDRLDFQDFKVSVKASDVFMAVEAYRLLAKQIVQPLHLGITEAGGLRSGTVKSAVGLGMLLAEGIGDTIRISLAADPVEEVKVGYDILKSLHLRSRGINFIACPSCSRQNFDVVKTMNELEGRLEDLLVPLDVAVIGCVVNGPGEAKEAHVGLTGGTPNLIYIDGKPAQKLTNDNLVDELEKLIRQKAAEKVEADAALIVRG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GCNFA_DANRE
Sequence: MVDKTHETEFSKKQLEASSSGHGGVLIDAEENGIHDQAEQRSCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCEMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISDEEIERIMSGQEFKDEANMPEHTWGNNGDSDHSSPGNGVSDGNQPSPVSTLSSNRSVELNGYTTALREQYIGNAMAQHYQFLPHLFGYAAQPRSLYPQSHTLIGQLVAAEDLAPLGTPMLIEDGYRVTQVELFALLCRLADELLFRQISWIKKLPFFCDLSIEDYTRLLSATWQELILLACLTVYSAQVLGDLANVTHKYTPSDDELHSFSEDGMEVMEKLIYLFRKFHQLKVSNEEYACMKAINFLNQDIRGLTNVTQLEQLNKRYWYVCQDYTEYKYPHQPKRFPEIMMCLPEIRCIAGKLVNIPLEQLPLLFKAVLHSCKSSLSSYRTSSSPCVTKGTAPAN
What is the function of this protein?
Probable orphan nuclear receptor.  Binds to a response element containing repeats of the motif 5'-AGGTCA-3' (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 6 group A member 1-A, Germ cell nuclear factor A, GCNF-A, zfGCNF.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCUP_AGRFC
Sequence: MSERKVMTVLNGKTVTPPPIWLMRQAGRYLPEYRETRKSAGSFLDLCYNPELASEVTLQPIRRFGLDAAILFSDILVIPDALHRNVSFSEGKGPAMDPIDISGIEKLDASDVMAHLSPVFETVSRLRTSLPDETTLLGFCGAPWTVATYMIAGHGTPDQAPARLFGYQEPAAMEKLLALLAEVSADYLVAQIDAGADAVQIFDSWAGVLGEKEFEEYAIKPVARIIASVRARRPSAKIIAFAKGAGYLLRDYRRKTGANAIGLDWSVPLSFARDLQKEGPVQGNLDPMLMVAGGKALQDGIDAVLQSLGQGPLIFNLGHGITPQADPENVTRLVQRVRSVGGAG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG46_MYCTU
Sequence: MSFVIAVPEALTMAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAAVAALFGSYAQSYQAFGAQLSAFHAQFVQSLTNGARSYVVAEATSAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGNGGNGGSGAPGQPGGAGGDAGLIGNGGTGGKGGDGLVGSGAAGGVGGRGGWLLGNGGTGGAGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGGVFGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGPLLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGGAGGQGGPAVAGVLGGMPGAGGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGPAGGVGEAGGVGGQGGLGESLDGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVGGAGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGAGGAGGTGGTGGGGAAGFAGGVGGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGGVGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGNGGAGGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGLIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGGTGATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPPGTQGADG
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS46.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: UFOG_SOLME
Sequence: MTTSQLHIAFLAFPFGTHATPLLTLVQKISPFLPSSTIFSFFNTSSSNSSIFSKVPNQENIKIYNVWDGVKEGNDTPFGLEAIKLFIQSTLLISKITEEAEEETGVKFSCIFSDAFLWCFLVKLPKKMNAPGVAYWTGGSCSLAVHLYTDLIRSNKETSLKIPGFSSTLSINDIPPEVTAEDLEGPMSSMLYNMALNLHKADAVVLNSFQELDRDPLINKDLQKNLQKVFNIGPLVLQSSRKLDESGCIQWLDKQKEKSVVYLSFGTVTTLPPNEIGSIAEALETKKTPFIWSLRNNGVKNLPKGFLERTKEFGKIVSWAPQLEILAHKSVGVFVTHCGWNSILEGISFGVPMICRPFFGDQKLNSRMVESVWEIGLQIEGGIFTKSGIISALDTFFNEEKGKILRENVEGLKEKALEAVNQMMEVQQKISRF
What is the function of this protein?
In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments.
What are the official names of this protein?
Anthocyanidin 3-O-glucosyltransferase, Flavonol 3-O-glucosyltransferase, UDP-glucose flavonoid 3-O-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: YA066_YEAST
Sequence: MFNRFNKFQAAVALALLSRGALGDSYTNSTSSADLSSITSVSSASASATASDSLSSSDGTVYLPSTTISGDLTVTGKVIATEAVEVAAGGKLTLLDGEKYVFSSDLKVHGDLVVEKSEASYEGTAFDVSGETFEVSGNFSAEETGAVSASIYSFTPSSFKSSGDISLSLSKAKKGEVTFSPYSNAGTFSLSNAILNGGSVSGL
What are the official names of this protein?
Putative GPI-anchored protein YAR066W.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: TGT_SYNSC
Sequence: MFGFEINAHCANTSARCGTFETPHGPVNTPRFMPVGTLATVKGISTEQLGRTGAQMVLSNTYHLHLQPGEEIVAAAGGLHRFMGWNGPMLTDSGGFQVFSLGDLNKIDDRGVVFRNPRDGRTIDMTPEHATQIQMALGADVAMAFDQCPPYPATENDVIDACRRTHAWLERCVTAHTREDQALFGIVQGGCFPHLRRESAMAVASFDLPGTAVGGVSVGEPAEEMHRIVRDVTPLLPSHKPRYLMGIGTLREMAIAVANGIDLFDCVLPTRLGRHGTVLVGGERWNLRNARFRHDHTPLDPSCSCVACTGHTRAYLHHLIRSEELLGLTLLSIHNITQLVRFTSAMAQAIRDGCFSEDFAPWEPDSPAHHTW
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ATPF_STAEQ
Sequence: MTATANTFILGAGVEWGTTFVTLVTFVILIILLKKFAWGPLKEVMDKRERDINKDIDDAEQAKINAQKLEEENRKTLKETQDEVQKILDDAKIQARKQHEEIIHEANEKANGMIETAQSEINSQKERAISDINNQVSELSVLIASKVLRKEISEQDQKELVEKYLKEAGDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TRPC_PROM9
Sequence: MEIRRRPPNPTVRVENLEYAVPHREAQAKNILEEIVWHKDIEIKNFKKIVSLEDLIKKIENLPDPKDFYKNILESKIKPGLIAEIKKASPSKGVIRKDFNPEDIAICYEELGASCISVLTDKRFFQGSYEILETVRKSTNLPLLCKDFIISAYQIYKARVSGADAILLIAAILSDDDLIYLKKIADNLKMSVLVEVHNDNELERILKLKSFNLIGINNRDLKTFKTDLKTSIELMHIYADIFLKQNILPISESGINCAQDLESLRSIGIKGVLIGETFMRESDIEKSFKKLFNSI
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: QUEA_CLOPE
Sequence: MKVSDFYFELPEELIAQYPLEKRDSSRLMVLDKKTGEIEHRKFHDILEYLNEGDTLVLNNTRVLPARLIGEKEETGGKIEFLLLKRIEGDKWECLAKPGRKAKVGTVFTFGEGKLKAIVREIGEEGNRIIEFKYDGIFEQVLDELGQMPLPPYIHEKLEDKERYQTVYSKEKGSAAAPTAGLHFTEELLKEIKDKGVNIAYLTLHVGLGTFRPVKVDDVNNHVMHSEYYHLDKENAELINKTKEAGKRVIAVGTTSSRTLETIGDENGRVREQSGWTDIFIYPGYKFKIVDNLITNFHLPESTLIMLVSALAGQDNIMNAYNTAVKEKYRFFSFGDSMFIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y465_AQUAE
Sequence: MNRQPMFFILIVLLFTVFSLKEFIPNTFCIHPKEGIIHLEKEHPKTFCEKDEVHVKVLSEIKNLKVQLDLDKSFSFTSPFRISLSFVVLKKQNALPEKSPRRESPIKTVRLLI
What are the official names of this protein?
Uncharacterized protein aq_465.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PFA4_GIBZE
Sequence: MAGLNDVPFIKGLAVPSVCALIIFLGYASQFLFNYSTTLEPGPPTRRETIIFNGLLLVLWITYYRTVATDPGRYIFKDRVIEAEGQRWCNKCAAPKPPRAHHCRHCARCVPRMDHHCPWTRNCVSMTTFPHFLRFLIYTNMSLWMLGYFLWQRFSKIWEHRRLPAYLGPSFYGLICLSLISIVNFVTTVALGIMLINTVKSWVFNQTMIEGWEQERHEALMDKGPKEWWDIMGPDGEKVRFERLEFPYDIGFFSNMAQAMGTHNVLLWFFPFAGNPTVAKDGNGQGWTWEENGFNRIEGLWPPPDPDKLRRAARGWPAGNRNYAEELRQANMSSSEYKAGFLKRQADDEKRKRHLMAELEEVDDFDMYDDEEYDRELDQGLGWVNSDGDRLRDYGVDEEASEPEGVNDDDDDDDDDDVPLAELIRRRKILKKDGLDD
What is the function of this protein?
Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
What are the official names of this protein?
Palmitoyltransferase PFA4, Protein S-acyltransferase, PAT, Protein fatty acyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RF3_DICNV
Sequence: MSDILSQDWRDRRTFAIISHPDAGKTTLTEKLLLFGGAIALAGAVKGRKAAHHATSDWMKMEQERGISVTSSVMQFPYHGKVINLLDTPGHEDFSEDTYRTLTAVDSALMVIDCAKGVEERTIKLMEVCRLRTTPIFTFVNKLDRDGREPMEILDEIERVLHIQCAPVTWPIGMGRSLKGIYHLARDTVYFYTTGKGGASINHGETVVGLDNPRLDTLLPDIIDDFREEIHFLREVGNPFDHEAYLRGELTPVYFGSAISNFGVEEMLTDFAQLAPPPRPHRTTEREVAPQEEKLTGFVFKIQANMDLKHRDRIAFMRVNSGTFRAGMKLWQVRLGREVKIPDALTFLAAEREHAQEAFAGDIIGIHNHGTIRIGDTFTEGESLQFTGIPDFAPELFRRVQLKDPLKMKALLKGLAQLCEEGATQFFKPLIGSDLILGAIGVLQFEVVQQRLETEYNVKCQFESVAVATARWIEAPNDKALKQFIDKNQANLAHDHYEQLVYIAPSRVNLQLTQERFPDIVFSQTRDHLAQ
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXH_ECOBW
Sequence: MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RF2_CAMC1
Sequence: MDSYEYNELLKKLQTKVENIGSIVKPDDIKARLKEIEAIEQDPDFWQDIARAGALNKEKTKISNMLAKFSDANQAVSDAKELFELANSENDEETINSLFEDAKNLDEKIVNLEISMLLSGEDDGKNAIVSIHPGAGGTESNDWASMLYRMYLRFCEREGFKVETLDFQEGEEAGLKDVSFIVKGENAYGYFKAENGIHRLVRTSPFDSAGRRHTSFSSVMVSPEVDDDIEIEIEEKDLKIDTYRASGAGGQHVNKTESAIRITHIPTGIVVQCQNDRSQHKNRATAMKMLKSRLYELELMKQQEASNSVEKSEIGWGHQIRSYVLFPYQQVKDNRSGEAYSQTDAILDGDIKKMIEGVLIAQKAEA
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_DESHD
Sequence: MSFSAETKDELARIEEGKRCCNLAELAALVRMDGTLQIANHSYALNVITESAPVARKVYRLAKNLLGLPVDIMVRRKLRLKKNNSYMVKIYPRTLEDLQQLGLLDEEGEILPGIPNVLVKKKCDRIAYLRGAFLAGGSINNPEGTYHLEIITNDPLHAEALSKLLNKFHLGAKVSMRKNWHVVYIKESEHIVEFLGFIGAHRALLEFENVRVLKDMRNQVNRLVNCETANLNKTVDAAVRQVENIQRVANTIGLQALPEPLREIAELRLEYPDASLKELGEMLVPKVGKSGVNHRMRKIDELAEKLEEQSKRVRKGG
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: CMOB_HYDCU
Sequence: MKHYHQHYSSFWPKLEEARLGHWQNALEAALETALDPDANGNLPKWLPALETVMAFPSSDSAELSQSAIKAHSQPFSEDDKEKLTQALKAFMPWRKGPFEIEGIYIDTEWHSDWKWDRVSPHLSSLKGRKVLDIGCGSGYHLWRMLGDGAELALGVDPGLLFMTQFLAIKHFVGESLPAYFLPLTLEQLPKTQPSEVFDTVFSMGVLYHRRSPIDHIMDLKRYLKPGGELVLETLVIPDAQGQLLVPKERYAQMNNVWFIPSVQELGHWLEKCGFKNVRCVDLDQTSVKEQRTTEWMNWNSLADFLDPNDSNKTIEGYSAPLRAVMIADKPC
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: SYR_CLOAB
Sequence: MDYKKVIAERINKIVDMDVEALYKIIEIPPKKDMGDFALPCFQFAKVLRKAPNAIAEEVCKKIDQSGFEKVENLGPYINFFVDKADFAKETIESVLSERDNYGRSKVGEGKKVLIEYSSPNIAKPFHVGHLFGTVLGSSLYKIFSMEGYDCVRINHLGDWGTQFGKLISAYKRWCDEDALYKDPIKELLRIYVKFHKEAEKDPLLEDEGRMYFKRLEDGEKEEVELWTKFKDLSLREFKKVYNQIGVEFDSYTGESFYSDKIDAIEEELNEKGLLTESNGAKVVMLDEYNMPPCIIKKADGASIYATRDLAAAEYRKKTYNFDKSIYVVGLEQSLHFKQFLKTLELAGHEWSKDCIHVGYGLVRFAEGKLSTRNGDVIFLEDLLKESVQKTSEIIEEKNPELDNKEEVSRKVGIGAVIFTYLKNGRERDIIFDWKEMLSFEGETGPYVQYSYARAKSILRKLGEVKGNVSYDKLVSAEEFDLIKQLKGFNGAILNAIDRLEPSVITRYVIEVAKAFNKFYNAYNISNTSDEELKNARLALVEAASIVIKNALSLIGIDVVEEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_MPRVN
Sequence: MSNTMPEGYIPRPGKDQTLEAYISEELSKHNLTFNDVLNNEEMMAELSKDDAFMKLKAEFENKDKPEVVEASSNKKEEKVSEPKVEEKKDPEPEKDAPALVVEEVVMDDDDADEVEKPTMEAPKSTVAKLTETQFRIDSSNLMSKIDFTIAYDKLMTVDSFGVEDLVTKSPFYATRLDKPRHMRMDEFCNEFIEPAIPSALGHPNSEGYTDMVGFDWEKNQYLNLYEELGRRSVEAIELDDDANAGDVIIGGVTSLSMIKQVNAIVHDAILPKGRLAYIMAQMRAARCLQFTRVANGQEATPEDKLQAYMDAYMNPTYTRALRIRTPEPRVVTYNKAIDYVMYRLTLNADNDFISPMVQISDSIDVGRGVRSRSYQAATTVMSVIASSHRNLERPMTSARAPAKVITAFTDLVAPPAAEAMQKLGSYCLGGRRAELTVDMTDPILQSTDSVLAPIAAAANLILLDTNRLGNDIKRTLVYRMLSPFYGTGTRAEVDRINFNNIPRIVLTPIPDRRGLHGRLANFIRRQLTKPAYGRMDRNDSRIWRADIQTTPMLPFVPAGGMTPLSMHIGDERLENQAYAPQANELKVSLMDFVKMFDLMHARQGKETYLSSQFSAILTNESSYLYNSISMVMRTMIRGWESLDLLPPLDGAVPGALEMDRTEAFVLPFTGAVSFICYGIEDDGLEYVPWEQRKEIPMPSSFPMLLDMEIRVANELLLEAADPAGRFTRSDMLINQDEFINMAEFIMKKYLTSIDGGEFGTRYRLHWYLFEGIRIHNRTLQTPGIEDLKVARRILDGVKYPEDIATAVYIKIYESVNPIDLVNPDPQRSDYQVYMEEIPADDEILEIKDIVTYRREDGGEDFNFTPYLHSGETFNLDLIRKLAKSIPGDHRYVKVPTKVTVKPVELLDNVDVIAEDFTVALKFKKGVNEMRFEASDIPLYYRWDKFNGRSQLTLDVRVFPDTNVLLDHVMESDPRMGYAPQVLNDGTVGWVSTLSGNVYLEERKVCRREEEVLKSGIDLLIDPYGV
What is the function of this protein?
Self-assembles to form an icosahedral capsid with a pseudo T=2 symmetry, about 60 nm in diameter, and consisting of 120 VP3 subunits.  The capsid encapsulates the genomic RNA (By similarity).
What are the official names of this protein?
Major inner capsid protein VP3.
What are the subcellular locations of this protein?
Virion.
Protein: EAT1_KLULA
Sequence: MFLSLRPSLSVSRLAVVRRAYSSPASKKQINDGLVPLPHKEVIDMAFDLHLPERSVIGKLPYHSPEPIIFFHGLLGSKRNYKHDCKKLATALQTPVYTVDVRNHGSSEHALPFNYGTLVNDLVHFIHQHKLGKVNIIGYSLGAKVGMLACLKHPELFSAACIIDNAPEPQPHIKAFLSTLIKSCVKLLDQGKVRVDDKLWRHKASESLKRYLPNAGVRNYVLNNIVHNPRVVEYRSPVINYDDGLIHFKNPVRHMLDCGVKDVADWPTEEVKDKKFLGPVNFIRATKSAFINPDSLKAINSFFPFNNIHEINATHFVLNERPQEYLRAVIDFFKVTRYQLENKRNKDPNNYMQTQNSISNSDTMGQSL
What is the function of this protein?
Alcohol acetyltransferase that catalyzes the synthesis of ethyl acetate from ethanol and acetyl-CoA (PubMed:28356220).  Can also function as a thioesterase by hydrolyzing acetyl-CoA in the absence of ethanol, as well as esterase hydrolyzing ethyl acetate (By similarity).
What are the official names of this protein?
Ethanol acetyltransferase 1, Acetyl-CoA hydrolase, Acetyl-CoA thioesterase, Alcohol acetyltransferase, AAT, Ethyl acetate esterase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ANFC1_TAKRU
Sequence: MLCPALLCAALLLLTPVEITDARALQQPSDAAQFMEQFLESYNDLLTLDDLENMLNSHPEDQSNLSSSKADEYPKWAEADTPWLRLLRGALANQKRAEPDRSRRGWNRGCFGLKLDRIGSMSGLGC
What is the function of this protein?
Exhibits natriuretic and vasodepressant activity.  Has cGMP-stimulating activity.  May help to regulate body fluid homeostasis in a variety of aquatic environments.
What are the official names of this protein?
C-type natriuretic peptide 1.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: NFYB6_ARATH
Sequence: MERGGFHGYRKLSVNNTTPSPPGLAANFLMAEGSMRPPEFNQPNKTSNGGEEECTVREQDRFMPIANVIRIMRRILPAHAKISDDSKETIQECVSEYISFITGEANERCQREQRKTITAEDVLWAMSKLGFDDYIEPLTLYLHRYRELEGERGVSCSAGSVSMTNGLVVKRPNGTMTEYGAYGPVPGIHMAQYHYRHQNGFVFSGNEPNSKMSGSSSGASGARVEVFPTQQHKY
What is the function of this protein?
Component of the NF-Y/HAP transcription factor complex.  The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.  Plays a role in the regulation of the embryogenesis.  Involved in the abscisic acid (ABA) signaling pathway.
What are the official names of this protein?
Nuclear transcription factor Y subunit B-6, AtNF-YB-6, AtNF-YB6, Protein LEAFY COTYLEDON 1-LIKE.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYL_ECO57
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVNTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPQWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.