PharMolix/UniProtQA huggingface dataset:
Protein: GCH1_BRUA4
Sequence: MDARILKEDDESGLPNKQADVTLLHGKPTQADAEAAVRTLLLWAGDDPEREGLLETPKRVAKAYKELFAGYTESPEEVLGTVFEEVGGYNDLVLVKDISFHSHCEHHMVPIIGKAHVAYLPDHKVVGLSKIARVVDIFARRLQTQESITAQIADSIQRILKPRGVAVMIEAEHMCMAMRGIRKQGSTTITTTFTGEMQVNAEEQVRFMTLTRR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: EPMA_HAEIG
Sequence: MTALNHWQPSADIKNLLKRAKIIAEIRQFFTERGLLEVETPVLSEFGVTDLHLSTFSTEFLAPFGEQSKTLWLSTSPEYHMKRLLAAGSGPIFQISKVFRNEEAGNRHNPEFTMLEWYRPHFHMHRLINEVDDLLQQILDCPPAESLSYQFVFQEYVGLDPLSAERSELIEAARKHNFMAEDNEDRDTLLQFLFSEVVEPQIGKERPIAVYHFPSTQAALAQVSPEDQRVAERFEFYYKGLELANGFHELADAQEQRHRFELDNQQRQKCELPTREIDERFLAALEAGMPDASGVALGIDRLMMIALDCEKINDVISFAVDNA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: GLMM_META3
Sequence: MKLFGTSGIRMKNLTPEIAYKVGFAVSQIAKNVVVGRDTRTTGDLIRNSLFAGLLNGGAEIVDIGIVPTPTLGYSARNYDMGIMITASHNPSEYNGIKLFNKDGTSFRPEQEQNIEDIIYNKKNQKRVSWNSIKKVWTDESALKKYSDFILDSVEINKNFSVVVDCANSAGCVASPYLFTDVGAHVISVNGHIDGRFIGRSPEPNEKNLQDTMHMIKGLNENNKGNKYIGIAHDGDADRMIAIDEKGRLTDFDKLLAVFSRYMAEKTGTKTIITTVDASMAIEEYLKDLNVNVIRTKVGDVAVSDELNKHDDAIFGGEPSGTWIHKDIHLTPDGILSGLRLLEMMEFYDKKLYELIDDVPCYSNLREKLPCPDDKKIIVMDFVIKNGENIFDAEVETIDGARFSLDDGWVLIRPSGTEPFVRVRVEAKNDIIAKELLEKGIKLVKDGLNEKK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ZAR1_MOUSE
Sequence: MFPASTFHPCPHPYPQATKAGDGWRFGARGCRPAPPSFLPGYRQLMAAEYVDSHQRAQLMALLSRMGPRSVSSRDAAVQVNPRRDASVQCSLGRRTLQPAGCRASPDARSGSCQPRGHAGAGRSPRSWQTVAPFSSVTFCGLSSSLEVAGGRQTPTKGEGSPASSGTREPEPREVAARKAVPQPRSEEGDVQAAGQAGWEQQPPPEDRNSVAAMQSEPGSEEPCPAAEMAQDPGDSDAPRDQASPQSTEQDKERLRFQFLEQKYGYYHCKDCKIRWESAYVWCVQGTSKVYFKQFCRVCEKSYNPYRVEDITCQSCKRTRCACPVRLRHVDPKRPHRQDLCGRCKDKRLSCDSTFSFKYII
What is the function of this protein?
mRNA-binding protein that mediates formation of MARDO (mitochondria-associated ribonucleoprotein domain), a membraneless compartment that stores maternal mRNAs in oocytes (PubMed:36264786).  MARDO assembly around mitochondria is directed by an increase in mitochondrial membrane potential during oocyte growth (PubMed:36264786).  Promotes formation of MARDO phase-separated membraneless compartment by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (PubMed:36264786).  Binds to the 3'-UTR of maternal mRNAs (PubMed:31598710).  Maternal mRNAs stored in the MARDO are translationally repressed (PubMed:36264786).  Essential for female fertility and oocyte-to-embryo transition by coordinating maternal mRNA storage, translation and degradation (PubMed:12539046, PubMed:31598710, PubMed:36264786).
What are the official names of this protein?
Zygote arrest protein 1, Oocyte-specific maternal effect factor.
What is the protein family that this protein belongs to?
Belongs to the ZAR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T229B_DANRE
Sequence: MATTVTPEPLTALSRWYLYAIHGYFCEVMFTAAWEFVVNCNWKFPGVTSVWALFIYGTCILIVERMYLCLKDRCNVLLRCIIYTLWTYFWEFGTGFLLRQFNACPWDYSEFKYNFMGLITAEYAVPWFCASFIVERLVIRNTLRLRFDEVAESGQAEERLDRGGGGRGGRRGRGARAGATSANGYVKVD
What are the official names of this protein?
Transmembrane protein 229b.
What is the protein family that this protein belongs to?
Belongs to the TMEM229 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FTSH_MYCTO
Sequence: MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQINGDNVKSAQIDDREQQLRLILKKGNNETDGSEKVITKYPTGYAVDLFNALSAKNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGFGFGKSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHSKGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTIITGPALEEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTTGAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQPDYSHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPELESIFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPVPEPAFKAAIAQATQAAEAARSDAGQTGHGANGSPAGTHRSGDRQYGSTQPDYGAPAGWHAPGWPPRSSHRPSYSGEPAPTYPGQPYPTGQADPGSDESSAEQDDEVSRTKPAHG
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: MURB_LIMRD
Sequence: MANLMNEFPDIEIKQDEPLMNYTYTKTGGPADWLAFPETIDQVKELVDYVREHEMGLTVLGNASNLIVGDGGIDDLTIILTRLNKIEVHDNKVTAQAGASYIATTEAARDSELTGLEFAAGIPGSIGGAVFMNAGAYGGETKNVVSEATVMLPDGTIKHLTNEELDFGYRHSSIQDNNGVVLDATFALEPGKYDEIKARMDDLNERREAKQPLDLPSCGSVFKRPEGYYAGKLIHDAGLQGYTSGGAQVSTKHAGFIVNIDHGTAADYVNVIHHVQKTVKEKFGVDLETEVRIIGRQD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNTB_YERE8
Sequence: MDVVAGKALQVSDAVYSYQLDGKGGVTSISPDAVATAEQPCWLHLDYTHPDSAAWLQNTPLLPEVVRDGLAGESVRPKVTRLGDGTMITLRGINFNNDARPDQLVTIRVYMTDKLIVSTRHRKVYSIDDVLNDLQSGTGPTNSGNWLVEIVDGLTDHTSEFIEDLHDKIIDLEDDLLEQKIPARGQMALLRKQLIVLRRYMAPQRDVFSRLASERLPWMNDDDRRRMQEISERLGRGLEDLDSSIARTAVLSDEISSLMADAMNRRTYTMSLLAMVFLPTTFLTGLFGVNLGGIPGNTDSFGFATFCMMLVVLVLGVAWWLKHSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTL_CITBB
Sequence: MATKIRILPENLTNKIAAGEVVERPASVAKELVENALDAGSKEVVVEIESGGRRLIKVSDTGCGMSRDDALLALERHATSKIATDEDLFSLCTLGFRGEALPSVASVSRLTISTRTSDSVEGTEIYAEGGRIKEVKECGMAVGTVISVRNLFFNTPARLKFMKSAETEGGHVGELLTRLAISRPEVRFTYKNDGKVVFRALDADLKERVATMLGRSIASFLYPVSYQEGGLKVSGLVAAPECSRSAGSHLYTYINGRFIKDKVVQHAILQAYRNFLERGRYPVVAVFIEIAPGEVDVNVHPTKHEVRFREQGRVHDAIQNAVESVLKETPWLKRPAVAAVSRPTEKDAAAARAVLEGSQAPLPVTPQPRPALTSEKPVPAPQAQPQQSSISEARVAEVRELLVDFQPRPQPSLRPQYQGSVTSKEALPYAPMAAPVPVREPETAAPEPDPAAAGYFSSLGVIGQFNASYILCQRGTDLVLIDQHAAHERVAFEKLKGQFAGREVDSQGLLFPETMEFSFRESAVLREHLAELARLGFEFEEFGGNTWLLKGVPQVLSATRYVDTIRDILEELGSLSRSRAFSDIQEDLLARIACHSVVRGKRTLSQVEITALFKQMDETDFSSNCPHGRPVMQTLTLAEVEKMFKRI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SYE_NOCFA
Sequence: MTEVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGTFVFRIEDTDAARDSEESYHAILDALRWLGLTWDEGPEVGGPYGPYRQSQRRELYLDVVRRLLEAGEAYESFSTPEEVEARHRAAGRDPKLGYDNYDRDLTPEAIEAYRAAGRPAVVRLRMPDEDLTWTDLVRGETTFKAGTVPDFALTRGNGDPLYTLVNPVDDASMKITHVLRGEDLLSSTPRQLALYAALRRIGVADFTPEFGHLPFVMGQGNKKLSKRDPESNLFAHRDRGFIPEGLLNYLALLGWSLADDRDVFSMSEMVAAFDISKVNSNPARFDQKKADALNAEHIRLLEPGDFAHRLRQFLTEHGHIGADVDEKVFAAAAELVQTRIVVLGDAWDLLRFLFAPADEFTVDEAAAAKNLGADAVPVLEAAIAALEPLPGWATPVIEDALKTALIDDLGLKPRKAFAPVRVAVTGSHISPPLYESLELLGRELTLARLRSGLEWARQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_RHOPA
Sequence: MIQMQTNLDVADNSGARRVMCIKVIGGSKRRYATVGDVIVVSIKEAIPRGKVKKGDVMKAVVVRVRKDIRRADGSVIRFDRNAAVLINNQSEPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14, RRP-L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: LIPA_STAAC
Sequence: MATKNEEILRKPDWLKIKLNTNENYTGLKKMMREKNLNTVCEEAKCPNIHECWGARRTATFMILGAVCTRACRFCAVKTGLPNELDLNEPERVAESVELMNLKHVVITAVARDDLRDAGSNVYAETVRKVRERNPFTTIEILPSDMGGDYDALETLMASRPDILNHNIETVRRLTPRVRARATYDRTLEFLRRSKELQPDIPTKSSIMVGLGETIEEIYETMDDLRANDVDILTIGQYLQPSRKHLKVQKYYTPLEFGKLRKVAMDKGFKHCQAGPLVRSSYHADEQVNEAAKEKQRQGEAQLNS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_TROWT
Sequence: MTKSNETERMEESEETHSSDIRSASESDHASGSDHTESADEIPTADAEQGELEQLEKLKDDLARERAAFHNFRMARAKQAEIERDRTRSEVIRVILPVLDDFARIEKHSTLDDPFKAVVTKLRSAMEKIGLTAFGNPGDPFNPELHEALFQNPSPDVQTETVQDVIEAGYCLGETVIRAAKVVVQVPNG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_AROAE
Sequence: MKQYLDLMRHVLDHGDRKSDRTGTGTLSIFGWQMRFNLDDGFPLLTTKKLHTRSIIHELLWFLRGDTNIRYLNENGVSIWDDWADENGDLGPVYGKQWRRWETANGATIDQIAQLIDGLKHNPDSRRHLVSAWNPGEVAGMALPPCHALFQFYVAGDRLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVCGLRAGDFVWTGGDCHLYLNHLDQARLQLSRQPRALPRMIVNPGVTDIFGFRFEDFRLEGYDPHPHIKAEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO6A5_HUMAN
Sequence: MKILLIIFVLIIWTETLADQSPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQIIKDVTKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQISTYAEQRNLDKTGCVDTKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRMSKVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGKEERVSFGQNFDALKSIKNEVVREICAEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHSKGARLGAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSLVFHVENFDHLKALERKLIFRVCALHDCKRITLLDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGNKNNTIYVDNFDKLKDVFTLVQERMCTEAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGGFPRIDFALKKVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKIITFQDFDKLKNVDVKKRIIREICQSCGKTNCFMDIVVGFDISTHVQGQPLFQGHPQLESYLPGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKFQIYQKAVFDSLLQVNVSGPTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNIMLENQSDRLREAGLDALLVVSLNTTAHHEFSSFEFGKRFDYRTHLTIGMRELGKKLSQYLGNIAERTCCCTFCKCPGIPGPHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSGPKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPGQNNNIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPGPTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPGLPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGPKGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPCWKEKCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGANVRRVAVFFSNGQTASRSSIITATMEFSALDISPTVFAFDERVFLEAFGFDNTGTFQVIPVPPNGENQTLERLRRCALCYDKCFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHLIQLGRIHKPDLNYIAKFLKPFLYSVRRGFNQYPPPMLEDACRLINLGGENIQNDGFQFVTELQEDFLGGNGFIGQELNSGRESPFVKTEDNGSDYLVYLPSQMFEPQKLMINYEKDQKSAEIASLTSGHENYGRKEEPDHTYEPGDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHLVQLGRTHKPDWNYIIKFVKPFVHLIRRAINKYPTEDMKATCVNMTSPNPENGGTENTVLLLPGIYEIKTENGDLFDEFDSQAQHLLVLGNNHSSGSETATDLMQKLYLLFSTEKLAMKDKEKAHLEEISALVVDKQQEKEDKEMEATDI
What is the function of this protein?
Collagen VI acts as a cell-binding protein.
What are the official names of this protein?
Collagen alpha-5(VI) chain, Collagen alpha-1(XXIX) chain, von Willebrand factor A domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the type VI collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Deposed in the extracellular matrix of skeletal muscle.
Protein: RSMG_CAUVC
Sequence: MQPDLALAPEAVLDAAGFQALVGATDAQIEDLTRFQTLLAEWNEVMNLVGPLTIATYWTRHALDSAQLIPLAPEATAWADLGAGAGLPGVVLAILLKGRAGAKVHLVESMIKRCRFLEVVAKDLDLPVQIHNARAEDLKLKVDIVTARACAPMTKLLGFAEPYLRNGAVGLFLKGQDVETELSEARKAWTFESELRTSQSDPRGRIVQVKRLSRVR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase, Glucose-inhibited division protein B.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_HAEDU
Sequence: MKVALGIEYDGSNYFGWQRQAEVVSVQQTLEEALSKVTNTTIEVFCAGRTDSGVHGTGQVVHFDTEVERPLASWCFGTNAHLANDIAVKWAVKVAEDFHARFSATARRYRYIIFNSKLRTAILPKGVAHYHYPLDAQKMHQAGQYLLGEQDFSSFRAAKCQSHTPWRNIHHLNVVRQGNYVIVDIQANAFVHHMVRNIVGSLLEVGQGRQPIEWIKWLLEQKNRQLAAPTTKAEGLYLVNVEYPSRFGIPKTALGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LACB2_XENTR
Sequence: MALSVLPRLEQLSARVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAVPEYISCLKQALTEFNTSIQEIIVTHWHVDHVGGIADICTDIMNGCNFSVSKLPRNPHQEEVIGAVEHKYNYLKDGDIITTEGATLRVLYTPGHTDDHMALELLEENAIFSGDCILGEGTAVFEDLYDYMKSLEKLLEMKADKIYPGHGPVVLGARAKIQEYISHRHAREQQILQALQENSGRSFTSMDLVKIVYKDTPEYLHKAAEFNLTHHLQKLKKEGKISEEQSPTVRWRSNL
What is the function of this protein?
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA.  The cleavage product contains a free 3' -OH group.  Has no activity with double-stranded RNA or DNA.  Required for normal mitochondrial function and cell viability.
What are the official names of this protein?
Endoribonuclease LACTB2, Beta-lactamase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ATPA_ANADF
Sequence: MEIRADEISRIIREQIKDYGKKVDVAETGTVLSQADGVARIYGLAGAAAGELLEFPHGTRGLVLNLEEDNVGAAIMGAFEHIREGDPVKRTGKIAEVAVGEELLGRVVDGLGSPIDGRGPVNAKHTRKIEIKAPGIVQRKSVHEPMQTGLKAIDALVPIGRGQRELILGDRQTGKTAVAIDTILNNKGNNLYCFYVAVGQKQSTVARVVEILKQHGAMEYTTVIAANASDPAPMQYLAPYTGVTMAEYFRDTGRHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSEKEGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESNLFYQGVRPAINVGISVSRVGGSAQIKAMKQVAGSLKLELAQYRELAAFAQFGSDLDKATQETLARGERLVELLKQGQYSPMPVEKQVIQIYAATQKDENGQGWIRQVPVEEVGRYMRELVEFLDARHPGVAKTIAEKKALDDGIRSQLDAALREFRGVFQVEGQA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATP6_WICCA
Sequence: MTNIIVNSPLDQFDIKVFIGFVSPFIDLTNINITTFTVYSVFILIVILGLTLLTDNNGRIIGNRWYVSQEAMYDTINNMVSGQIGGKLGGYYFPLIYTFFIFIFTANLIGMIPYSFAITSHMVFIISLSVVIWLGVTIIGLYTHGLTFFALFVPAGCPLALAPLLVLIELLSYSARAISLGLRLSANTLSGHLLMVILGGLVFNLMSVSIVTFVLGFIPLAGILAIVALEFAIAMIQSYVFAILASGYIKDGLYLH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COPZ_STAAM
Sequence: MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
What is the function of this protein?
Chaperone that serves for the intracellular sequestration and transport of Cu(+).  Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA) (By similarity).
What are the official names of this protein?
Copper chaperone CopZ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YH049_YEAST
Sequence: MTRSKRRLILKFNMISFFSAVSLLHYFLPSRKSISMFKKVFVSHAKAPRVDFSRRAGLAARRMEEKRKDATNLWFILYKVLICIYTYSISISLHTPCV
What are the official names of this protein?
Putative uncharacterized protein YHR049C-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRPD_PELPD
Sequence: MIKKAIARIVEQKDLTEGEMIEVMGQIMTGEATPAQIGAFITALRMKGETIDEITGAARVMREHATRIRAGKDLLDIDRDDINIDRETILDVVGTGGDGTNTFNVSTTVAFVVSACGVKVAKHGNRSVSSLCGSADVLEKLGVNLDITPETVEQCITKIGIGFLFAPALHGAMRYAIGPRREIGIRTIFNILGPLTNPAGADCQVMGVYRPGLVEKLAGVLHRLGCRHGFVVHGMDGMDEITTTTETLIAEVTTSGVSICTIHPEELGFSRCSMDELRGGDATANADIVRSVLQGVAGPRRDIVLINAAYALVAADRAATPEQAIALAAEAIDSGRAMEQLRKLIQITKD
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: Y2940_MYCS2
Sequence: MSGHSKWATTKHKKAVIDAKRGKMFAKLIKNIEVAARVGGGDPGGNPTLYDAIQKAKKSSVPNDNIERARKRGAGEEAGGADWQNITYEGYGPNGVAVLVECLTDNRNRAAGEVRVAMTRNGGNMADPGSVAYLFSRKGVVTLEKNGLTEDDVLLAVLEAGAEEVNDLGDSFEIISEPSDLVAVRTALQEAGIDYDSADASFQPSVTVPVDLEGARKVLKLVDALEDSDDVQDVYTNMDIPDDVAAQLDEE
What are the official names of this protein?
Probable transcriptional regulatory protein MSMEG_2940/MSMEI_2866.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_BUCAI
Sequence: MRHYEIIFMVHPDQSDKIPLLIEKYKKIINDNNGIIHRLEDWGRRQLSYSINKLQKAHYILMNIEVFPKTITLLETDFRFNNIILRNMIMSVKKAIVELSPILKLKDDKKEKK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: NUOC_RUEPO
Sequence: MSDALRELGTHLELKRADCILSWDVTFGELNVDVAPSNLVDFVDFLRSDSSCRFSTLVDITAVDYPERAKRFDVVYHFLSMYQNQRIRLRVSIREDDMVPSITDVHPSANWFEREVFDMFGILFTGHPDLRRILTDYGFRGYPLRKDFPTTGYTEVRYDEAEKRVVYEPVSLVQEYRQFDFMSPWEGADYILPGDEKKEG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.