PharMolix/UniProtQA huggingface dataset:
Protein: ISPD_MANSM
Sequence: MTRHSRPIIAVVPAAGVGSRMQADKPKQYLTLLGKTLLEHTLEVLLSYTPIQQIILAVAENDPYLDQLDVIRQPKIKIVQGGRDRAGSVFNGLKAITQPHAWVMVHDAARPCLTHEDLDKLLQIEDDNGGILAIPAVDTIKRASAEKQIIQTEDRSQLWQAQTPQFFRADLLYRALQQAFEHGLAVTDEASAMEFAGFRPHLVAGRSDNLKVTRPEDLKLAEFYLSRK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RL7_XANCB
Sequence: MSLTNEQIVDAIAEKSLMEVMELVKAIEEKFGVSAAAPVAAAAAGPAAVVEEQTEFTVVLTSPGANKVAAIKAVRGVTGLGLKEAKDLTEAGGILKEGVSKDEAEKIKKEMTEAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TATB_XYLFA
Sequence: MFDIGFSELLLIAVVALVVLGPERLPKAARFAGLLVRRARTQWESIKQELERELEAEALKRNLENAQQVIHDAQAQLQSNQQDMNIQNSISILHEQTKRDIHPDRNTNTLELGTAVHHVHVTSPPPSTSTHGNNGQEKSQ
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TM109_MOUSE
Sequence: MAGAHSTPLWSRHLLKAVLMVLVALFLVHSASAQSHREFASPGQQKKETSADILTQIGRSLKEMLDTWLGPETMHVISETLLQVMWAISSAISVACFALSGIAAQLLSALGLDGEQLTQGLKLSPSQVQTLLLWGAAALVIYWLLSLLLGLVLALLGRILGGLKLVLFVAGFVALVRSVPDPSTRALMLLALLTLFALLSRLTGSRSSGSHLEAKVRGLERQIEELRGRQRRAAKMPRSMEEE
What is the function of this protein?
May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death (PubMed:20060811).  Can form voltage-gated calcium and potassium channels in vitro (By similarity).
What are the official names of this protein?
Transmembrane protein 109, Mitsugumin-23, Mg23.
What are the subcellular locations of this protein?
Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y712_PSEAE
Sequence: MNVSKPEQRTLHALAQGGHIAFLRDASGKITRVECYNRDGHLLLDCTLAVFSRLKNKGLVHSRQGRPYRISMAGLKAVRPQADNR
What are the official names of this protein?
UPF0386 protein PA0712.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: HBSAG_HBVC5
Sequence: MGGWSSKPRQGMGTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDQWPEANQVGAGAFGPGFTPPHGGLLGWSPQAQGILTTVPAAPPPASTNRQSGRQPTPISPPLRDSHPQAMQWNSTTFHQALLDPRVRGLYFPAGGSSSGTVNPVPTTASPISSIFSRTGDPAPNMENTTSGFLGPLLVLQAGFFLLTRILTIPQSLDSWWTSLNFLGGAPTCPGQNSQSPTSNHSPTSCPPICPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLLPGTSTTSTGPCKTCTIPAQGTSMFPSCCCTKPSDGNCTCIPIPSSWAFARFLWEWASVRFSWLSLLVPFVQWFVGLSPTVWLSVIWMMWYWGPSLYNILSPFLPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: RL2_SYNC1
Sequence: MAIKKYKPTSAGRRHMTSADFADITAAKPEKSLVEKLNKSGGRNNAGRITKRHTGGGHKRKYRVIDFRREKKEIPAKIASIEYDPNRSARIALACYADGEKRYILAPLGLKVGDVVIASEQADIKPGNALSIRSIPLGTWVHNIELKIGKGGQLARSAGTYAMIAAKEGKYAQLRLPSGEVRLVLQDCCATVGQVGNVQHENVKIGKAGRNRWLGKRPQSRGVAMNPVDHPHGGGEGKSSGGRHPVTPWGVPTKGYKTRVNKRTDRFIVRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y7416_DICDI
Sequence: MTTIGPIENEIKELLTKELNPINLEIINESYMHNVPKGSESHFKVKIVSEKFETLSMIEQHRLVNEILKNFIGNGKIHALSITSRTPTQWKKNNQTKINVDDDKSPSCKGGFGK
What are the official names of this protein?
BolA-like protein DDB_G0274169.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
Protein: RL22_ACTP2
Sequence: METIAKHRYARTSAQKARLVADLIRGKKVAQALEILTFTNKKAAALVKKVLESAIANAEHNDGADVDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL27_BIFLO
Sequence: MAHKKGASSSRNGRDSNPQYLGVKKFGGEAVVAGNIIVRQRGTNFHPGHNVGMGKDHTLFALTDGSVKFGVRRDRKVVDVIA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y2299_ANOFW
Sequence: MGLFLYLLFMIVVGAFIGGMTNSLAIKMLFRPYRPIYIAGKRLPFTPGLIPKRREELAEQLGRMVVEHLLTAEGLRRKLNDPSFVQDMTSYVQEEVEKWLQSDRTVEQWLKQFGMPDPKQTAETWIETKYKTFMSQYRQRPLHEIIPIDVLHKIDHAIPSIVDRLLLRLRTYIESEQGERQIEHMINEFLQSRGMFGNMLQMFLGNVSLAEKIRPEIVKFLQSEGAKQLLVQLFINEWEKVKEMRIHEVEQIIDQEKIVVWVKRLTASIVQEPLQKPLGALVAPYVRHSLPTLVRFLLQFASERIERWMKQLHLQDIVREEVASFSVERLEEMILTISRREFKMITYLGALLGGIIGLIQGCITFFVQM
What are the official names of this protein?
UPF0754 membrane protein Aflv_2299.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YEL1_YEAS7
Sequence: MCASLNEVKKNDTYGVSQKGYNDNFSESEGVLHGSKSMPTSMKNMLQSPTMVNMCDILQNKEAANDEKPVIPTTDTATAGTGTEDISSTQSEETDQNSHLIASEILEGTFKDVSYKEYANFLGNDNNNQVLTEFVKLLSPLPSSLLETLFNLSKSIYFIAEAQNIDRILECLSIEWIACHPNTHWKSGYKSCHIVLFSLLILNSDLHNNFQVDHKKIKFSMVAFINNTLRALREENEYEELKIYSREHLIIEELSEYYKTLNETPLPLCTESRTSINISDNQSSLKRFSTLGSREFSTSNLRSVNSNSTTLYSRDGQVSVREMSAKSNKNFHNNHPMDALYLKESFDDGLITENGSSWFMDDLILISKKSLPRKYSKRDKDQVAAPKMTSKRNKSFFGWLKPSKTTTLIEHTSRRTSLSYLNKDSEWERVKIQVKEGRIFIFKIKPDVKDIIQSSETDSATIDYFKDISSSYFAYSLLEAEAHVVQDNIIIGSGAMKSNVCNKNTKRKSGNFTVSFPENINGPKLVLEFQTRSVEEAHKFMDCINFWAGRISPVPLTQFEAVSNAEYGWSDKILTEHASLNLKNIVVSEWKPLLGLELLYEDAKDVEMVELKERLKELMNFTRQLGIWIDKHNEIKDKLVEIWSFDDNYFEAVMNNWNSRYLYMNNQYKKRLSYLKALQKAMGSVQF
What is the function of this protein?
Guanine nucleotide exchange factor for ARF3 required for localization of ARF3 to the bud neck and tip and involved in actin patch polarization.
What are the official names of this protein?
Guanine-nucleotide exchange factor YEL1, EFA6-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the YEL1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Bud neck. Bud tip. Note=Localizes at the cell membrane only at the bud neck and bud tip and this localization is ARF3-dependent.
Protein: ATPF1_AZOC5
Sequence: MSDMELAELWVAVAFFVFVGILLYNGVHKALAKALDARGARIAAELDEARRLKEEAQKLVAEYKRKQREAEAEAEAIVTAAKAEAERLAAETKAKLEEFVSRRTRMAEDKIAQAEHQALADVKAFAADAAVQAAERILAASVPGTATGDRLLGQAIQDVRGKLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SRY_TURTR
Sequence: MFRTVNGEDYSPAVQQRNILDFGKAHSLLWTDNGSANDRCETGGNCRESGQDRVKRPMNAFIVWSRDQRRKVALENPQMQNSEISKRLGYDWKMLTEAEKQPFFEEAQRLRAMHRDKYPGYKYRPRRKAKEATEIASRRLFSTVQPNAHRGDVVPLPIQGRLRQGHTFTNGKPVKPLTAHEHKQLTPATGASQQLDKPAPQ
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: EFTU_OLTVI
Sequence: MAREKFERSKPHVNIGTIGHVDHGKTTLTAAITMAMSVFSGAGAGKKYDEIDSAPEEKARGITINTAHVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQTKEHLLLAKQVGVPKIVVFLNKKDQVDDDELLELVELEVRETLDNYEFDGDDIPIIPGSALLALEALIESPEAKKGDNEWVDCIYSLMENVDSYIPTPERDTDKPFLMAVEDVFSITGRGTVATGRVERGVVKIGDTVELVGLKDTTETTVTGLEMFQKTLDESVAGDNVGILLRGVQKENIQRGMVLAKPGSISPHTKFEAQVYVLTKEEGGRHTPFFPGYRPQFYVRTTDVTGKIESFVADDGSASQMVMPGDRVKMLVELINPIAVEKGMRFAIREGGRTVGAGVVSEILA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MOBP_HUMAN
Sequence: MSQKPAKEGPRLSKNQKYSEHFSIHCCPPFTFLNSKKEIVDRKYSICKSGCFYQKKEEDWICCACQKTRTSRRAKSPQRPKQQPAAPPAVVRAPAKPRSPPRSERQPRSPPRSERQPRSPPRSERQPRSPPRSERQPRPRPEVRPPPAKQRPPQKSKQQPRSSPLRGPGASRGGSPVKASRFW
What is the function of this protein?
May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
What are the official names of this protein?
Myelin-associated oligodendrocyte basic protein.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Note=Present in the major dense line of CNS myelin.
Protein: Y3932_BORPA
Sequence: MTDSHRPDADDIPDDDELSTDFSNQFLLAMPGVVEGSLAGTVIYICEHTRRGALGLVINRPTDLTLATLFERIDLKLEIGPVKDEMVFFGGPVQTDRGFVLHAPAGDYTSSINLGELALTTSRDVLQAVADGNGPARMLVTLGYAGWGAGQLESEMAQNSWLSVGADSHIIFDVAPEDRYPAALKLLGVDPVMLAGGAGHA
What are the official names of this protein?
UPF0301 protein BPP3932.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: OLF1_MOUSE
Sequence: MTERNKTVISQFLLLGLPIPPEHQQLFYALFLVMYLTTVLGNLIIIILIILDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVPSIPYAGCLAQIYFFLFFGDLGNFLLVAMAYDRYVAICYPLHYTTIMSPRLCVSLVVLSWVLTTFHAMLHTLLMARLSFCEDNVIPHYFCDMSALLKLACSDTRVNEVVIFIVASIFLVLPFALITMSYVRIVSSILKVPSSQGIYKAFSTCGSHLSVVSLFYGTVIGLYLSPSSNNSTVKDTVMSLMYTVVTPMLNPFIYSLRNRDIKGALERVFCKRKIQLNL
What is the function of this protein?
Odorant receptor.  Activated by a lily-derived aldehyde as well as other odorants.  May signal through an inositol 1,4,5-trisphosphate (IP3) second messenger system (By similarity).
What are the official names of this protein?
Olfactory receptor 1, Odorant receptor I54, Olfactory receptor 135-13.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSN31_PIG
Sequence: MVCGGFACSKNALCALNVVYMLVGLLLIGVAAWAKGLGLVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNHHQVLLFFYMIILGLVFIFQFGISCSCLAINLSKQAGIIN
What are the official names of this protein?
Tetraspanin-31, Tspan-31, Sarcoma-amplified sequence homolog.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NRSF_AZOOP
Sequence: MKTEDLITMLAAGAGAVEAPSAAQRYALAIGWGAAGATLLMLALLQVRHDLGLALLLPMFWVKVGFVTCLAAGSLFAVLRLSRPGAKTNWVPAALGLPVLGMWAIAAFTLIEAEPMERSNLFFGDTWKSCPLLIAMLSVPVFAAVLRSMKDLAPTRPRLAGFAAGLLAGAVAAVVYCLHCPELGAPFIGFWYLLGMLIPAAVGVLLGNSMLRW
What is the function of this protein?
Probably an anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-F (SigF), which responds to (hypo)chlorite.  ECF sigma factors are held in an inactive form by a cognate anti-sigma factor (Probable).
What are the official names of this protein?
Probable anti-sigma-F factor NrsF, Negative regulator of sigma F, Regulator of SigF, Sigma-F anti-sigma factor NrsF.
What is the protein family that this protein belongs to?
Belongs to the NrsF anti-sigma-F factor family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVB_LACLS
Sequence: MNDILNKEPMEEDYGIEKSLRPQFFNQYIGQDKVKEQLEIFIKAAKMREEVLDHVLLFGPPGLGKTTMAFVIANELGVNIKQTAGPAIEKPGDLVAILNELEPGDVLFIDEIHRMPMQVEEVLYSAMEDFYIDIMLGSGDGSRSVHLDLPPFTLVGATTRAGMLSNPLRARFGISSHMEYYQERDLEEIVKRTADIFEVEVIDNAAIEIALRSRGTPRIANRLLKRVRDFAQIMGDGRVDKAITDKALTILDVDAAGLDYIDQKILRTMIEMYHGGPVGIGTLAVNIAEDRETVEDMYEPYLIQKGFLMRTKQGRKVTQRAYEHLGYVYNEEE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: SYS_SULIN
Sequence: MSWSILEFLRKNPEELKNNLKRRAIDVSLVDKAVELDKKWRQVLQEVERLRHQHNVLSSQIPKLSGEERKKKIEESKNLLKILEDKEKELEKIEVERDRLLSSLPNLVADDVPNGPDDSYNIPIKFWGKFKVYEGDVEEFLRQTKDANVNYEIIKWKPKGHAEMLEDVLHLGNTLKAAEIAGSRFYYLFNDIVWLDFALLLFAIDYITQQGYTLVLPPYMLRGEVIQSVIDLDTFKDAIYKIENEDLYLIATAEHSIAAMFFKEEIEKDKLPLKFAGISPAFRKEAGAANKDLKGIFRVHQFHKVEQFIFSTPEDSWKYHAELITNAESIFQQLELPYRIVNIASGDLGACAAKKFDLEVWMPAQAKFREMVSCSNCTDWQAFRMKIRYVDRKNNKRGYVHTLNSTAIASTRTITAILENYQREDGVVEVPKVLRKYLEIFPKAPKDYIYPLKNKII
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMC_PSYIN
Sequence: MSLANHTFSNPSRVLQRNESLFTNKNILVAGNIDDEYPLQLQALANSSTFCFSDYRYYSVLKDKLTTSEVHFTDNYQGETKFDLLLIFLPKAKQETLYLLANLTPHLQPGASIILVGEKKCGIKSADSLLASYSNRINMIDSARHCSILHAELNQPVNAFTQSQWIKTYPLNINNTELQICSLPGVFSYGELDKGSELLLQNLPDKMSGRVLDFGCGAGVIACYVLKKHPQLSVDLVDINAFALASAKLSLQSNQLEGNVFPSNVFSDIKEKYNILLSNPPFHSGKNTDYTAAETFINQSTNHLKSKGKLSIVANRFLNYEGLLFKAFSNVKIDQESNKFKVLSCITKT
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B_ROSNE
Sequence: MPPKAADKKPAAKAPVASKAPEKKDAGKKTASTGEKKKRTKARRETYSSYIYKVLKQVHPDTGISNRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSTK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: XGPT_ECO81
Sequence: MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CYAY_RICTY
Sequence: MNNTAFSKLAETTIVYIVDKIEEQDIEGIIDVDLHGDILNLDTENGIYVINTQSASKEIWLSSPVSGPHHFFYEQGKWKSRIGFELMILLTEELGIRFDKCEIF
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: SNU71_YEAS7
Sequence: MRDIVFVSPQLYLSSQEGWKSDSAKSGFIPILKNDLQRFQDSLKHIVDARNSLSETLLNSKDDGSIHNSDQNTGLNKDKEASIADNNSANKCATSSSRYQELKQFLPISLDQQIHTVSLQGVSSSFSRGQIESLLDHCLNLALTETQSNSALKVEAWSSFSSFLDTQDIFIRFSKVDEDEAFVNTLNYCKALFAFIRKLHEDFKIELHLDLNTKEYVEDRTGTIPSVKPEKASEFYSVFKNIEDQTDERNSKKEQLDDSSTQYKVDTNTLSDLPSDALDQLCKDIIEFRTKVVSIEKEKKMKSTYEESRRQRHQMQKVFDQIRKNHSGAKGSANTEEEDTNMEDEDEEDDTEDDLALEKRKEERDLEESNRRYEDMLHQLHSNTEPKIKSIRADIMSAENYEEHLEKNRSLYLKELLHLANDVHYDHHRSFKEQEERRDEEDRAKNGNAKELAPIQLSDGKAISAGKAAAITLPEGTVKSENYNADKNVSESSEHVKIKFDFKKAIDHSVESSSEDEGYRESELPPTKPSERSAAEDRLPFTADELNIRLTNLKESRYVDELVREFLGVYEDELVEYILENIRVNQSKQALLNELRETFDEDGETIADRLWSRKEFRLGT
What is the function of this protein?
Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA.  Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway (By similarity).
What are the official names of this protein?
U1 small nuclear ribonucleoprotein component SNU71.
What is the protein family that this protein belongs to?
Belongs to the SNU71 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYP_SHELP
Sequence: MRVSKYLLSTQKETPANAEVVSHQLMLRAGMIRRNASGLYSWLPSGLRVLRKVEAIVREEMNNAGAVEILMPMVQPADLWVETGRWDKFGPELLRFQDRHNRDFVLGPTHEEVITDIIRKEVSSYKQLPLNLYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHLDQETMDDTYQAMYTAYSNILGRMGLAFRPVLADTGSIGGSMSHEFHVLANSGEDLIAYSTESDYAANIEKAEAPMPTEPRGAATMEMSVIDTPNAKTIEELVEQHGIAIEKTIKTIIVKGASEEAPLVAVIVRGDHELNEVKVEKLDAVLAPFEMAGEAEIRDALGAGPGSLGPVGMTIPVYVDHSVNVMSDFAAGANQDGKHYVGINWERDLPQAEVADLRNVIEGEPSPCGKGTIGLLRGIEVGHIFQLGTNYSKAMGASVLDENGKAQTLLMGCYGVGVSRIVAAAIEQNHDDRGIIWPAAIAPFKVGILPMNMHKSHRIKDMAEKLYSDLSDAGIEVLFDDRKERPGVMFADMELIGLPHVIVIGERNIDNGVFEYKNRRTGEKQEIPFEEIVDFIKSAK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP9A_CONLT
Sequence: MTLTKSAVLILVLLLAFDNFADVQPGLITMGGGRLSNLLSKRVSIWFCASRTCSTPADCNPCTCESGVCVDWL
What is the function of this protein?
Probable neurotoxin that inhibits ion channels.
What are the official names of this protein?
Conotoxin Lt9a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin P superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NO29_XENLA
Sequence: MSGFISSTAAQGPPSPAIESYLFGCELSSKTKQYTFEVNEEDDAVHLVCLQTISLGAGAKDEHNVVEVTAPNYQNKEVTVPLANLKLSCQPMVNVGYFEIEAPVTFRLTSGSGPVFISGRHYVVASDDEDLSGSEEEMEDEEEEEDDDDDDDDDDDDDDDDDEEEITPIKPAKKPLKTLSRTF
What are the official names of this protein?
Nucleoplasmin-like protein NO29, NOVA.
What is the protein family that this protein belongs to?
Belongs to the nucleoplasmin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.