Protein: R1A_BRV1
Sequence: MSKTSRELTNETELHLCSSTLDLISKSQLLAQCLGTPQNLVSLSKMVPSILESPTLEPRYTSTHSSSLQSLQLLALNTSSTLYKWTTGSISKLRGHLERELCRGLVPLNDFIPKGNYVELSLMIPSVLTGQGTSTTTTLQEMCSDMVQSCIKSMETDLLKGVLALKDQTSCQEYFLSANYQSLIPPQPLVNAMRMSSVVDLSPLILENTRLLLKLSPFHGGTSVSYTSMIREFVDCSRRDEKCLKRRLTKKQKRQEEGSFDANKVITLGGKMYRYRVVILKCSDEVDDLIGFDGKVGEFDYNFENVPHCWRDLVKRRCLIRAKATWNLAGGVDENLDHVYIDESQXDFRCADGSSDSPSACVEDPHLEERIFSRVWLKQTSRFFGTKIQQVSELFKSIGLPELETTYCGVNPVKVGNKWLSFRDQGRSRVFFVYTDSNVYLATTRQKVCCDYILTKFKSVKWIGNKPDQCRVVKVLAWLISVNKVKNCTRVITPMLTVQGKISHRRVDYLDISVLDSYVSDTAGLNCVQKVKKFLSMYYNCGADLGLLDNFLTPIECGTKQLVFERCNCPNHQFYVAQFDNHVVLGLGRPTGVVYPEEIPSCANIYAVGFATQKRVVEVHYYSEMDRHQLPQDYYYFAYDQEFQHVGGDDYVNHHLDDVEDQPFPPVLFDDVYDSGDSLDDGGSDLDCFDVGYDFFWPEAPIPVPSPYGYYQGQRLRDLCVAGGDFGCDCPRCDGTFIYHPFRPRHYHSFDEVGPFIQMCEFTLTYSGQNYNLFYGLEPKVCLQDLVEASDKLLQLLVRGQLENISLPNDILACLSSLKLGANIHPFLWPAPFFNANGEWVDIFGGGDFTVFGEDFCLKAKSMVESVYFLVENFFSVDCPIGNLYCNLHLDGDVKKMLWSTIHMKYIYLALIHSEKVFNIILNSRQLSHQELVKLVIIGTFDVSIVAPCACSGDCNHGKVYNWTNLLSSVYRFVTLDQLVGLSYCEKRSLVLRKVQQYLEVEEGYQRPVQLLMAPFYGFNDNAEPDEQPLTGVFHQQVMQMFDTCVMLDVICGLKRPRASVYNLFGVLADYFRRPFTFRYYQVAEFSGSESTQVFTDVTSALTSKDPCSNRPYIYHDYAVCRVVEPRTAAVTTRGAIYPPEVIEMIRSYLPIEFDVGVMNYVDGNCDFKYCNLEFCLSGRGLVKLDTGELLDYKTNLFVVRYKTLPLLYVTSNPIYLSDFSLDNAVCLTGDFKLSFDVEPGSTLFGLYFTNGRCYRDVWETLPRFGLGTLSPPKCHSKCEPFENLAEVFFFKRRVQLVPLVNNYTPVFRHRPDIPKVLTVELMPYYSSIGYQGFVAPKCVLPGCVATQYCKLRHQLDRCVQVTKLAVAYAFYFKPLNIGSLYHLDPMRGTSYGKPAVVQFEPVGLIKEVNILVYQFGKHVAIHYFPECPTYVAYGHYPSHSVGVWLGYLPSVEECVIAQRNYRVYVPTCFRLSRTGCYHIQQDEDFERTHITVSYHYARDFDTKSLTPMFQMFSKIFGKSKQDLICALNSLSEESQSVLTLFCEEFDSAYTLQTISDEVSFETSTSPELVACVLAYAIGYELCLTVKTDGECESLDVGSSLEQVYVDYDVSKNVWDLSTHLQDDSSDDLELPFNQYYEFKVGRASVVLVQDDFKSVYDFLKSEQGVDYVVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYIKQYKKLGVTCAIRSPGFQLGKGVQIIHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVLTSMLSTGIFGCSVTDSATTLLSNLVDLDKDVVVFVVTNVSDQYIEALGVVESFQSAHGLPNFGNTCWFNALYQLLKSFAVKEQIVQDLVNCFDDFYECPTRQCVEWVCDQLGVVFGEQYDAVEMLVKIFDVFKCNVRVGYDCLARLQQVALGSCREVPADAVLMFFGQDKSGHWVAARKVCGVWYTFDDKVVVKKDPDWSKVVLVLRERGLFKATDFETPRPRRRRVAYRVPRDTISQDAIMFLEERQFSSGTMLAHSCVESVESFHVEGVQPSPLQSVDGLDDVADLSCDNHVCDNSDLQEPQVVVSQPSEVLTTSMSIECPVLENSECSVETDLNPVCEENEQVGESGIKEQDGVTTSDSQQVFSKSLDPIIKQHEVESVEPQDLPVFSQQPQVMLSMTWRDVLFQQYLGFKSDLLSLTHVNKFKIVVYLMVLWFVLLYCFSDFSLLSRFCLYVFLLWLSHVVLVVKKLDLGLVNSGGESYVLRILSSVKVPNCIAFNCDGVHWLILKLLFYSFHFYDFFVKTLVVVFQMPQLRCFTWPLLKLGFADTFLSHHILAFPTKQVSQSCLPVFGDERKYIYVPYWCKESFRTLVARAKQLTATGRTKTLDNWHYQCCSKTVKPSSCFNVRDFVFDDACNNHKHYGFFSALWFYVVFYSGFVSFWLPLMFCYCALFMCTFKNLPVNITRPIRWTVLQQVVDDLLSIITKPLFGRPACPPLSAYLTATTADEAVRASRSLLGRFCTPVGFQQPIMNVENGVAVSSLGFINPLMWPLFIVVLLDNRFVWFFNVLSYIMLPVFVIILFYFYLRKICGCVNVKGVVKNCTRHFQNFSKPLVAAGVHGNRTNFTYQPMQENWCDRHSWYCPKEEHYMTPEMAMFIKNYYNLATSPMADTIWCDYVKSVPNMTWANFKFSLFKSNETVMCGPSSHADSMLLSWYAFLHGIRFAVNPSVIDIPSQTQPIYVSSDSDDSLDKGCDVSLRPTKNKGKFKKQSVAYFSAGPVDLWYYVMLIIALGAIFVFMYSCFMVGQYVVMPRDKFFGVNPTGYSYVNAQPYLHASPPVLRNSDGMVLATPLKVPSISYSVYRLLSGHLYFTKLIVAENECTPPFGAXRLSHEFTCNDFTYILPAHLRIFGRYIMLIHPDQLHMLPFEVEHSTHTRLCYVTGTNIVECLPTFEIISPYVFVVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVFKLLFVNTVMVLFVVCLPPLVPGVVFVLALWLCDSVVFLLYLAVLSLFILPWFYVMLFVLIVGGFVFWWMMKSSDVVHLTPDGLTFNGTFEQVSKCVFPLNPLIVNRLLLDCRMSHSDLVEKSKLKTTEGKLATEMMKVFMTGETAYYQPSNFSFQSVFSKVVSPFTLHARPPMPMFRLYVYFNGQCVGTTCTGTGFAIDDSTIVTAKHLFECDDLKPTHLSVELSCRSYWCTWKEPNVLSWKFEGENAYISVENLRDFYGIDFKYLPFQQIECEFYKRMEAVTIYSIKYGSEFATQAWQTVNGHFVCCNTEGGDSGAPLVWRDSVIGVHQGLCDSFKTTLASDSKGVMMTEVKGYHVDPPVYYKPIIMSAAYNKFVADSDVSVGECTNYHNFVNEDFFSMHDELEKVSFGDKMFRYCQSLPRYLEPLHYFHVPSFWQPFKKQSVSSNVSWVVENLHFIFSVYFLVCDFVAYWWLDDPFSVVLPLFFVVQLLSTVVLKNVLFWNTSYLVTLAVTFYVHSEVAESMYLLGLFSDQIVNRVGLILVVSVMCLFVVVRVVVNVKRAIFVVVVSVLLIVVNVVLGVVQFNSLVAVCMFDIYAVFAALLTPQPVVAIMMLILFDTKCLMSFAFVVIVLSFRVFKNYKFVRVLHNLCNFDFVLTQLSLFRYRHHNQGNNPSHYEALWLFLKELYYGVQDVKYEVFSPQAGTYNVRFLTDMTEQDQLEAVEQVQRRLQRFSIVQDKNSQRLVLYSKNVDFLRSQIQHQRVLGANPFIITTLTPKDIAIDNVEVHNPSQFKPEDLQAHMWFYSKSPIFVGQVPIPTNVQTAAVLDTTYNCQDLTADEKNNVAANLQIQNAALTLSLFEECNRFLESELGDVPTLMWQSEDVVDVKQLEVQIEKLRVVLDGMQLGTSEYKATRKQINILQSQLDKALAFERKLAKFLEKVDQQQAITNETAKQLSAFKNLVKQVYESYMSSLKVRVVESNDASCLLTSTDLPRKLVLMRPITGLDNIKIVEKANGCEITAFGDTFTTGLGSNLAGLAYSSTQPLSAYPFIFNLEGIFKQQANIGYKTVECNMSSDNGSVLYKGKIVAVPSEDNPDFVVCGKGYKLDCGINVLMIPSIVRYITLNLTDHLQRQSLKPRRRLQYKQQGVRLGGVNLGEHQAFSNELISSVGYTTWVSSTVCTDKSHKHPWFVQIPSSEKDPEWFMHNTQVKNNQWVVDAKPTHWLVDADTNEQLFALALTDEEYLKAESILAKWSPITQDVECWFKDLRGYYTVSGLQPLWPVCPKKICSLKIVPIFQSQSVAYADEPTHFLSLPVVNKNFLEAFYELQEGFPGEKQVAPHISLTMLKLTEEDVAKVEDILDEMVLPNTYATITNPHMMGQYYVFEVEGLQALHDEVVSVLRQHGIACDQTRMWKPHLTIGEIKDGSVFNKFKDFGITCKLEDCDFVKLGAPKANARYEFIATLPVGDLNC
What is the function of this protein?
The 3C-like serine proteinase is responsible for the majority of cleavages.
What are the official names of this protein?
Replicase polyprotein 1a, pp1a, ORF1a polyprotein.
What are the subcellular locations of this protein?
[Non-structural protein 1]: Host membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Non-structural protein 2]: Host membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Non-structural protein 4]: Host membrane; Multi-pass membrane protein.