PharMolix/UniProtQA huggingface dataset:
Protein: DHI1_RAT
Sequence: MKKYLLPVLVLCLGYYYSTNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDMAFAERFVVEAGKLLGGLDMLILNHITQTTMSLFHDDIHSVRRSMEVNFLSYVVLSTAALPMLKQSNGSIAIISSMAGKMTQPLIASYSASKFALDGFFSTIRKEHLMTKVNVSITLCVLGFIDTETALKETSGIILSQAAPKEECALEIIKGTVLRKDEVYYDKSSWTPLLLGNPGRRIMEFLSLRSYNRDLFVSN
What is the function of this protein?
Controls the reversible conversion of biologically active glucocorticoids such as 11-dehydrocorticosterone to corticosterone using NADP(H) (PubMed:12460758, PubMed:8613810, PubMed:14973125).  Participates in the corticosteroid receptor-mediated anti-inflammatory response, as well as metabolic and homeostatic processes (By similarity).  Bidirectional in vitro, predominantly functions as a reductase in vivo, thereby increasing the concentration of active glucocorticoids (PubMed:12460758).  It has broad substrate specificity, besides glucocorticoids, it accepts other steroid and sterol substrates (PubMed:14973125).  Interconverts 7-oxo- and 7-hydroxy-neurosteroids such as 7-oxopregnenolone and 7beta-hydroxypregnenolone, 7-oxodehydroepiandrosterone (3beta-hydroxy-5-androstene-7,17-dione) and 7beta-hydroxydehydroepiandrosterone (3beta,7beta-dihydroxyandrost-5-en-17-one), among others (By similarity).  Catalyzes the stereo-specific conversion of the major dietary oxysterol, 7-ketocholesterol (7-oxocholesterol), into the more polar 7-beta-hydroxycholesterol metabolite (PubMed:14973125).  7-oxocholesterol is one of the most important oxysterols, it participates in several events such as induction of apoptosis, accumulation in atherosclerotic lesions, lipid peroxidation, and induction of foam cell formation (By similarity).  Mediates the 7-oxo reduction of 7-oxolithocholate mainly to chenodeoxycholate, and to a lesser extent to ursodeoxycholate, both in its free form and when conjugated to glycine or taurine, providing a link between glucocorticoid activation and bile acid metabolism (By similarity).  Catalyzes the synthesis of 7-beta-25-dihydroxycholesterol from 7-oxo-25-hydroxycholesterol in vitro, which acts as ligand for the G-protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2 (EBI2) and may thereby regulate immune cell migration (By similarity).
What are the official names of this protein?
11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11-beta-HSD1, 7-oxosteroid reductase, Corticosteroid 11-beta-dehydrogenase isozyme 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: PRVA_LITCT
Sequence: MHMTDVLPAGDISKAVEAFAAPDSFNHKKFFEMCGLKSKGPDVMKQVFGILDQDRSGFIEEDELCLMLKGFTPNARSLSVKETTALLAAGDKDGDGKIGMDEFVTLVSES
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin alpha, Parvalbumin pI 4.97, PA 4.97.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: PNTB_ECO57
Sequence: MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVGFNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNRHKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQDDPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL
What is the function of this protein?
The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.
What are the official names of this protein?
NAD(P) transhydrogenase subunit beta, Nicotinamide nucleotide transhydrogenase subunit beta, Pyridine nucleotide transhydrogenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the PNT beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SODM_LISIN
Sequence: MTYELPKLPYTYDALEPNFDKETMELHYTKHHNTYVTKLNEAVSGHPELAEKPVEELVANLDSVPEDIRGAVRNHGGGHANHTLFWSILSPNGGGAPTGDLKSAIESEFGTFDDFKEKFNAAAAARFGSGWAWLVVNNGKLEIVSTANQDSPLSDGKTPVLGLDVWEHAYYLKFQNRRPEYIDTFWNVVNWDEANKRFDAAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: EFP_AZOVD
Sequence: MKTAQEFRAGQVAMINGEPWVIQKAEFNKSGRNAAVVKMKLKNLLNGQATETVYKADDKFEPVILERKEVTYSYFADPMYVFMDNEFNQYEIEKDDLGDAYNFIEDGMQDVCEAVFYNDRVISIELPTTIVRQISYTEPAVRGDTSGKVMKVARLNSGYELRVAEFCDIGDYIEIDTRTFEYKSRAKA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_GEOMG
Sequence: MSSDIHSEKILILDFGSQYTQLIARRVREAHVYCELHPFDMDLAAIRAFAPRGIILSGGPKSVYEEGAPAVEEALFELGVPVLGICYGMQLMSRHFGGQVVPAGKREFGHADLLAVGTPGPLFDGFFVEGKSPVWMSHGDHVSLVPAGFQVVGETANAPVCAIQDLARNLYGVQFHPEVNHTPRGELLIDTFVRKICGCSGQWTPGHIIDDAVSRIRAQVGNDRVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDNGLLRLSEGDQVMATFAENLGVKVIRVDAEDRFLTALAGESDPEKKRKIIGKLFVDIFEEESNKITDARWLAQGTIYPDVIESAGAKTGKAHNIKSHHNVGGLPDYMKLKLLEPLRELFKDEVRAIGEELGLPHQMVWRHPFPGPGLGVRILGEVKKEYADILRRADAIYIEELYAAGHYDKISQAFAVFLPVKSVGVMGDGRTYEYVVALRAVETKDFMTAGWYPLPYEDMARISSRIINEVKGVNRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RHAM_SHIF8
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGVHNYAIYLDKARNLLFAMVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_FRATT
Sequence: MVVIRMARGGAKKRPFYRIVVADKRSPRDGRFIEKLGFFNPLAKGGEERLKLDVAKAEAWLAKGAQPSDRVASLIKEAKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PSAJ_SYNS9
Sequence: MKKFLTTAPVVAAIWFTATAGILIEWNRFFPDLLFHPM
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: KDSB_YERPN
Sequence: MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATIPWERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDLDRVRAIMLNQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_KORCO
Sequence: MARSGRYKVKFRRRREGKTDYMKRLALLKSRKPRVVVRRTNRYIIVQFIGFKGEGDEVIAYAFSKELEKYGWPYGGKNLPAAYLTGYLAAMRAKKAGVTEAILDIGRFPSTKGSRLYAALKGVLDAGIDVPHSPEILPDEDRIRGEHIASFAEKLEEEGSLERQFSDYLRRGADPKIISEAFESVLERISAMSNG
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GBPA_ALIF1
Sequence: MNKSSTKTLIALSMMAVSSGVSAHGYVSETNDGIAGSRAALCKFPTSDTQEKNRDCGAVQWEPQSVEGPEGFPEKGPADGQIAGAGLVQFSELNEQTADRWVKRPITAGAQTFEWTFTANHVTRTWKYYMTKQNWNPNAVLTRDSFDLTPFCELEYNMEKPPLYPNTFSHECIVPEREGYQVILAVWDVGDTAAAFYNVIDVKFDGNGGVVDPTWSQGGQINPTRDLNVGDRVFTRVFDTSGENASLSTELVIENETQGQANNWTHALATKINKEQQNIGAGQLNDKGEFSPQYGSNPVYLKAGSGLKSVEIGYQLETVEPVYHLDIEGLASEYTIGDSATELDLSLYATGDMNVELTVYNHGKEALANTNVTLKDGEAKSVVMALSKSEKGHHMLVSRIKNMDGELIKQDMSDFHLVEEAVTPPPSGDFDFVFPEGVKGYKAGTKVLAEDGNVYQCKEFPYSGYCVQWTETATNFAPGVGSDWSMAWDKVN
What is the function of this protein?
Probably interacts with GlcNAc residues.  May promote attachment to both epithelial cell surfaces and chitin.
What are the official names of this protein?
GlcNAc-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the GbpA family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSB_PSEF5
Sequence: MTRSPIRRLVFGTLRRLLYLWVRSETINQSSFTLDLDRSRPVFYVLQNPSLTDLAVVDTECTKAGLPRPVLPVSVGNLLEPAAFFYLTPEPDWLGRQDKRGAPPTLTRLVSALTQNAAEDAQIIPVSVFWGQSPDSESSPWKLLFADSWAVTGRLRRLLSIMILGRKTRVQFSAPINLRELIEHNKGHERTVRMAQRILRVHFRNLKAAVIGPDISHRRNLVKGLLNQPLVKQAILDEAEREKISPEKAKAQALRYGNEIASDYTYTAIRFLEVVLSWFWNKIYDGIKVNHLEGVQKIAQGHEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGGLLRRGGAFFMRRTFKGNPLYTSVFNEYLHTLFTKGFPVEYFVEGGRSRTGRMLQPKTGMLAITLRSFLRSSRMPIVFVPVYIGYERVLEGRTYLGELRGASKKKESIFDIFKVIGALKQRFGQVAVNFGEPIKLAEFLDQEQPDWRTQELGPQYRPAWLNETTNRLGERVAQHLNEAAAINPVNLVALALLSTTRLALDDRAMARVLDLYLALLRRVPYSPHTTLPEGDGRALIQHVKDMDLLAEQSDALGKILYLDEQNAVLMTYYRNNVLHIFALPALLASFFQSSSRMSREQILRYTRALYPYLQSELFIRWPLDELDAVVDQWLEAFVEQGLLRFEKDLYQRPAPSSRHFVLLTLLSKSIAQTLQRFYMAISLLLNSGQNSISAEELEDLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDQGVLRRDEAGKLSYHEALGELAEGAAKRVLPAEIRLSIRQVALHRSEDAADQLAAPAQND
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VATA2_TREPA
Sequence: MIKDDVVTGRVVRVSGPIVYAEGLSACSVYDVVDVGEASLIGEIIRLDESKAVVQVYEDDTGMRVGEKVTSLRRPLSVRLGPGLIGTIYDGIQRPLERLFQEDGAFLRPGARSQPLDGSVRWDFRPHCNERGEALCAGIPIAPGSVLGTVQETPSVVHTIMVPPDIRGSVLSSFKGAGAYTIDEEIGRTDLGEPLFLSQYWPVRRARPFSKKLAVCEPLVTGQRAIDVFFPLSKGGTAAIPGGFGTGKTMTQHAVAKWCDADIIVYIGCGERGNEMTDVLSEFPKLIDPRTGRSLMERTILIANTSNMPVSAREVSLYSGITLAEYYRDMGMHVAIMADSTSRWAEALRELSGRMEEMPAEEGFPAYLPTRLAEFYERAGRVETCVAREGSVSIIGAVSPLGGDFSEPVTQHTKRFIRCFWALDRELAHARHYPAIGWIDSYSEYAQEVSAWWSKYDPRAGALRAAALDLLRKEQRLQQIVRLVGPDALPGEDRLVLMVCEMIKGGFLQQNAFDPTDVFSCPEKQVQILRTIVDFHERAVVLLRAGISLSALSQLSCRELIVRMKTTYGNEDVHKMQKVYDTMCTEFDQLSVCAAARTQGGEKVE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit (By similarity).
What are the official names of this protein?
V-type ATP synthase alpha chain 2, V-ATPase subunit A 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CMOB_ENT38
Sequence: MIEFSNFYQLIAKNHLSHWLETLPAQVAAWQREQLHGKFKQWSNAVEFLPEMTPYKLDLLHSVTAESEEPLSDGQLLRLDKLMRNLMPWRKGPFSLYGLNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPMQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALAAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNGGELVLETLVIEGDENAVLVPGDRYAQMRNVYFIPSALALKNWLEKCGFVDVRIADVCVTSTEEQRRTEWLTTESLAEFLDPNDSTKTIEGYPAPMRAVLIATKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: SYP_NITEU
Sequence: MRVSQFFLATLKEAPAEAELISHRLMLRAGLIKRLGSGLYTWMPLGLRILHKIEHIIREEMNNSGALELLMPAVHPAELWQETGRWDVFGPQMLKIQDRHKHDFCFGPTHEEVIVDIARREIKSYRQLPINFYQIQTKFRDEIRPRFGVMRAREFIMKDAYSFHADVDSLEQTYRLMQETYSRIFTRIGLKFRAVAADTGAIGGSGSHEFHVLADSGEDAIAFCPASDYAANIELAEAVPHGIPRKEPAGIMAKIATPDRKSCQDVADFLGIPVEQTLKALAVTAGGKFYLLLLRGDHQLNETKVRKIPFLGDFEFAEESRIIAEMSCPPGYLGPVGVKAEIIADRAVLEMSDFTCGANEEGFHLSHVNFGRDLPLPDQVFDIRNIVAGDPSPDGKGVLEICRGIEVGHVFQLRTKYSEKMKATYLDESGQTRIMEMGCYGIGVSRIVAAAIEQNYDERGIIFPQTIAPFQLSIIPVGYHKSQQVRTEAEKLYQACRSAGIEVLLDDREERPGVMFADQELIGIPHRIVIGERNLREGMVEYQGRLDKTPQMLSLSEAASIISKICGD
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLSA_YERPG
Sequence: MTTFYTVISWLSVFGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSFGELHLGKRRAERAKAMWPSTARWLSELKECQHIFANSNSEVASPLFQLCERRQGINGVKGNQLQLLTTTDDTLKALVRDIELARHNIEMVFYIWQPGGLVDQVAESLMAAARRGVHCRLLLDSAGSKQFFRSPYPAMMRNAGIEVVEALKVNVFRMFLRRMDLRQHRKIVLIDNYVAYTGSMNMVDPRFFKQDAGVGQWIDMMARMEGPVATTLGIVYACDWEIETGKRILPPPPDANIMPFEEETGHTIQVIASGPGFPEEMIHQALLTAVYAAREQLIMTTPYFVPSDDLLHAICTAAQRGVDVSIIVPRENDSMMVRWASRAFFTELLNAGVKIYQFEGGLLHSKSVLVDGQLSLVGTVNLDMRSLWLNFEITLVIDDDGFGADLAQVQDDYIARSALLDGERWNKRPLWHRVTERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCH1_HAHCH
Sequence: MLDKLVAQYSAIIESLGEDVNREGLRDTPKRAAKAMQFLCRGYNQSLEEVTNGAVFESDTDEMVLVKDIELYSLCEHHLLPFIGRCHIAYIPNGKVLGLSKFARIVDMFARRMQIQENLTRQIAEAVLEVTNAHGVGVIIEARHMCMMMRGVEKQNSVMSSSVMLGSMRNNPSTRSEFLTLVHSRRAL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: PCD10_HUMAN
Sequence: MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFLLAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDLMFLKPCSPSRSTDTEHNPCGAIVTGYTDQQPDIISNGSILSNETKHQRAELSYLVDRPRRVNSSAFQEADIVSSKDSGHGDSEQGDSDHDATNRAQSAGMDLFSNCTEECKALGHSDRCWMPSFVPSDGRQAADYRSNLHVPGMDSVPDTEVFETPEAQPGAERSFSTFGKEKALHSTLERKELDGLLTNTRAPYKPPYLTRKRIC
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.
What are the official names of this protein?
Protocadherin-10.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RAD59_CANGA
Sequence: MDGKVTYEGAVYSSGPGVEVGDIVFVEDWDGRPASEWSVQRIGVLQSKIERYTYQIYHSNRYGKHNLSKLIPRHVLVGFANEVFGFDGWKTDIEFVETKDGFPGSTSSISIADKISADSGGGTGALADRYTVIAEASVKVTLKDGTNTRMTGFSRATTPSKIESFNKAKKEAVNDALKKALLSFEKIILEHELKTKNDFYVDGLYGSKAQKI
What is the function of this protein?
Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing.  Anneals complementary single-stranded DNA (By similarity).
What are the official names of this protein?
DNA repair protein RAD59.
What is the protein family that this protein belongs to?
Belongs to the RAD52 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APAH_BURM9
Sequence: MTNFSSSPPIAFGDLQGCHAAYRQLFDTLAPAADTPLWFAGDLVNRGPASLATLREIAALGERAIAVLGNHDLHLLAVAAGIRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGMLMVHAGLLPQWDAALALELADELQRALRASNWRDTLRSLYGNDPNCWSPDLKHADRLRVAFNAFTRIRFCTPEGAMEFRANGGPAAAPAGYLPWFDAPGRKTADVTVVFGHWAALGLMLRENLVALDSGCVWGNRLSAVRLADDPAARVVTQVACERCGAADE
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: PLMN_CAPHI
Sequence: DLLDDYVNTQGASLLTLSRKKLAGRSVEDCAAKCEEEAQDCYHGNGQSYRGTSSTTVTGRKCQSWSSMIPHRHQKTPESYPNAGLTMNYCRNPDADKSPWCYTTDPRVRWEFCNLKKCSEDSE
What is the function of this protein?
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation.  In ovulation, weakens the walls of the Graafian follicle.  It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5.  Cleavage of fibronectin and laminin leads to cell detachment and apoptosis.  Also cleaves fibrin, thrombospondin and von Willebrand factor.  Its role in tissue remodeling and tumor invasion may be modulated by CSPG4.  Binds to cells (By similarity).
What are the official names of this protein?
Plasminogen.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasminogen subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface (By similarity).
Protein: CB21_ARATH
Sequence: MATSAIQQSSFAGQTALKPSNELLRKVGVSGGGRVTMRRTVKSTPQSIWYGPDRPKYLGPFSENTPSYLTGEYPGDYGWDTAGLSADPETFAKNRELEVIHSRWAMLGALGCTFPEILSKNGVKFGEAVWFKAGSQIFSEGGLDYLGNPNLIHAQSILAIWAVQVVLMGFIEGYRIGGGPLGEGLDPLYPGGAFDPLNLAEDPEAFSELKVKELKNGRLAMFSMFGFFVQAIVTGKGPIENLFDHLADPVANNAWSYATNFVPGN
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated (By similarity).  Mediates rapid phosphorylation and migration of LHCII-PSII to photosystem I (PSI) after transition to state 2 (red) light conditions, thus leading to the formation of PSI-PSII-LHCII and PSI-LHCII supercomplex to balance the relative excitation of PSI and PSII (PubMed:23995216, PubMed:23888908, PubMed:25194026, PubMed:26392145).  Involved in the production of reactive oxygen species (ROS) and stomatal closure upon abscisic acid (ABA) treatment.  Required to prevent water loss (By similarity).
What are the official names of this protein?
Chlorophyll a-b binding protein 2.1, chloroplastic, Photosystem II light harvesting complex gene 2.1, Protein LIGHT-HARVESTING CHLOROPHYLL B-BINDING 2.1.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FABH_STRT2
Sequence: MAFAKISQVAHYAPAQVVTDDDLSKIMDTSDEWIRSRTGIQERRISLNENTSDLATNVAYQLLEKSGLSPEELDFVLVATISPDNSMPSVAARVQGTIGAVNAFAFDITAACSGFVFALATAEKLIKSGAYKKGLVIGAEVLSKTLDWSDRATAVLFGDGAGGVLLEESEEEHFFGESLNTDGSKGGLESGASAVISPYSDGTEQPNPYMQMDGKAIFDFAVKTVSKSIKALVEEKGEPDYFLLHQANIRILDTMAKKIDVSRDKFLANMMSYGNTSAASIPILLSENVANETLKLGSDQTILLSGFGGGLTWGSLIVKI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DB124_HUMAN
Sequence: MTQLLLFLVALLVLGHVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKPPPVPKHEYE
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 124, Beta-defensin 24, DEFB-24, Defensin, beta 124.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBM48_RAT
Sequence: MASSDGKPGGIFDHHVQTAVCDSRAKYREGRRPRAVKVYTINLESQYLLIQGVPAVGAMKELVERFALYGAIEQYNALDEYPAEDFTEVYLIKFVKLQSARIAKKKMDEQSFFGGLLHVCYAPEFETVEETRKKLEERKAYISRVTKNQDYYVTKKKPVPEQKGTKDSRQDFHAHMPGFCTPALNTSPKNPSENSSPCLPYSCEFPLCYFASKSPCSPGEHTDKASDSCNSARNRGELQKHRDHSAFPPKLQMNTYKTSVPCSSVQEAIATSQAVGRFMPRTTQLQERKRRRDCDRELGTFLETNISSNEVLIGPKLPGIPTVDLQDDSLNTTANLIRSKLKEVTSSVPKPPEDNGEDVCTSHPRKQRRRI
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
RNA-binding protein 48.
What is the protein family that this protein belongs to?
Belongs to the RBM48 family.