PharMolix/UniProtQA huggingface dataset:
Protein: RS10_STRP3
Sequence: MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: BRE1_DEBHA
Sequence: MDHDNDKKRLHEDSDNSEIKKHKPLDVLSEDGPLTQKDVVYFKKEAIWRQMRSYKQKCTLLTRDLNDIKSNYESNERKINVLDSWYESIINLFGVKKESNVELNETILIQLTNVPIGDLDALLEKRRAQLLTILSPIIENSKLSNIDKSDVLEKIEVLNAEVATLKSENNTLSKLKSQFESKVEDLQAQLLTLVKDNDRRSSKTLQRIDESLTNGSDVKEEASETVKSEVNKDTTVKNENSVDNEEFERISSEIEELKSDNRLLKESMNQINTNYDKVVKENLQLSDKLENLNENDLINSVSYQELAAHNKQLNESVNNLQKINDTTVNKLNELENKQTNVKHLLDKELREENETLKQQLQKSENDLVRIRTARDELLSKQTILKADFENQTTNDELNKLNKVLNERINALESERHETGDNSKISELSKDELIQRINMLNSEIKEIEQAFQETRENSLSKLMSVTDQENMVKKLTIEKTKADQKYFASMRLKDSLSSENKILKTQINKSQELVSKLNDLEKSYLDKIEILTKSNNDFKIIRQSALQENSKLQESLRAIDVRKASLEKELSGMKDKYSDKVQENTSFTQELNEKNLMMGKLEHKLKSTESLLKKYKTNNTSSILQEDERQLEALRSIAKCSVCSKNWKDTAITVCGHVFCSGCTQERLAARLRRCPTCNKGFSANDLLSIHL
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1.  H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
What are the official names of this protein?
E3 ubiquitin-protein ligase BRE1, RING-type E3 ubiquitin transferase BRE1.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HCP_VIBVU
Sequence: MFCIQCEQTIQTPAVKGCSFAQGMCGKTAEVSDLQDVLVYSLQGVSYWATQAHRYGIINDEINQWAPKAFFSTLTNVNFDPERILQLTSQAAQFKAQLKDQVLTASSLANSPLSEVPAVAEFELPENAQAILAFAPQVAVNRGKEGVHEDVIGLRLLCLYGLKGAAAYMEHARVLEQTNNDIYAEYHEIMAWLGTDPEDLGELLDCSMRIGLMNYKVMEMLDHGETATFGHPVPTAVNVKPVKGKCILVSGHDLHDLEKILQQTEGKGINVYTNGEMLPAHGYPELNKYPHLVGNYGSAWQNQQKEFANFPGAIVMTSNCLLNPNVGQYADRLFTRSIVGWPGVAHIEDDDFSAVIESALAQPGFQHDEIEHMITVGFGRNALMNAAPAVIDQVKQGNIKHFFLVGGCDGDKAERSYYTDFTEAAPEDTLILTLACGKFRFNKNTFGDINGIPRLLDVGQCNDAYSAIQLALALAQEFDCGINELPLTLVLSWFEQKAIVILLTLFALGVKGIYTGPTAPAFLTPNLIAIIQEKFDMRSIGNVQDDLNTILAA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2398_PSEPK
Sequence: MFPAMLNVGLGLRRGLLPELLAMEAGAVDFLECAPENWIAVGGAYGKGLAQLAERFAVTCHGLSLSLGGSAPLDRHFLEQTRQFLDRYQVRLYSEHLSYCSDDGHLYDLMPIPFTDEAVRHVAARIRQAQEQLERRIAVENISYYAAPYQAMSELDFIQAVLEEADCDLLLDVNNVYVNACNHGYDAQQFLAGLPQARVAGMHVAGHYDEAPDLKVDTHGAAVKEDVWALYASACARFGVQPTVLERDFNYPPLAELLAETARMRAVQCAAGGQADE
What are the official names of this protein?
UPF0276 protein PP_2398.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: RL33_RHOP2
Sequence: MAKAVTIKIKLVSTADTGFYYVAKKNSRTMTDKMTKKKYDPVARKHVEFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: YCIN_ECOLI
Sequence: MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLVFTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD
What are the official names of this protein?
Protein YciN.
Protein: CAS1_SOLTU
Sequence: MASLLRRRFYSSESSFAQRLRDLPKYLPGTNIKTQVSQLIGKTPLVYLNKVSEGCGAYIAVKQEMMQPTSSIKDRPAFAMINDAEKKGLITPGKTTLIEPTSGNMGISMAFMAAMKGYKMILTMPSYTSLERRVTMRAFGADLVTTDPTKGMGGTIKKAYDLLESTPNAYMLQQFSNPANTQAHFETTGPEIWEDTQGNVDIFVMGIGSGGTVSGVGQYLKSKNPNVKIYGIEPTESNVLNGGNPGPHEITGNGVGFKPDILDMDVMEEVLMVSSEESVNMARELALKEGLMVGISSGANTVAALRLANRPENKGKLIVTIHPSFGERYLSSVLYEDIRKEAQNMQPVSVD
What is the function of this protein?
The cyanoalanine synthesis reaction is more efficient than the cysteine synthase activity.  Probably involved in detoxification of toxic cyanide produced in plant tissues.
What are the official names of this protein?
Bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RSGA_PSEE4
Sequence: MAKRQLNRRQNWRIEKIQGERAARAAKREQHVLQELEGGDLGPEQLGLVIAHFGVQVEVEAQDGEAAGQVFRCHLRANLPALVTGDRVVWRAGNQGIGVIVAQMPRSTELCRPNNHGQLKPVAANVDLIVIVFAPAPEPHPNLIDRYLVAAEHAGIRPLLLLNKADLINEENAPTLNAMLEVYRNLGYPLLEVSAHQGDGMQRLQQMLDGHISVFVGQSGVGKSSLVNSLLPDAGTRVGDLSEWSGQGTHTTTTARLYHFPNGGDLIDSPGIREFGLGHVSRDDVEDGFIEFRELIGNCRFRDCKHDREPGCALLKALEDGQVSQQRMSSYRSIIASLPEDSY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5C_SYMCR
Sequence: MEQTYQYAWIIPFLPLPVPMLIGLGLLLFPTATKSLRRMWAFQSVLLLSIVMIFSMNLSIQQINSSSVYQYVWSWIINNDFSLEFGYLIDPLTSIMSILITTVGILVLIYSDNYMSHDHGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPVAAKACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFQIFNNLISTNQVNFLFVTLCAVLLFAGAIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFIVIPHIMNFISLIGIITVFLGATLALAQKDINRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSVIHSMETLVGYCPKKSQNMVLMGGLTKHVPITKNSFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIAWSTAGLTAFYMCRIYLLTFEGHLNVHFQNYSGKRNTPLYSISLWGKEGSKISNKNFRLVTLLKMNKTGRPSFFSNRVYKIDENVRNMTPPFLSIPNFGNIKTSLYPYESDNTMLFPILILFIFTLFVGFLGIPLNQDVDILTKWLTPSINLLHKNSNNSIDWYEFCKDALFSVSIASFGIFIAFFLYKPVYSSFQNLDLINSFFKMGPRRNFYDKIKNAIYDWSYNRGYIDAFYGTFFIVGTRKLAEFTHFFDRRIIDGIPNGVGLISFFVAEVIKSVGGGRISSYLFFYFSYVSIFLVIYYFLNL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PTTG1_BOVIN
Sequence: MSTLIYVDKENGEPGIHVAPKDGLKLGSVPSVKALDGRSQVSTPHVGKMFDAPPALPKTARKALGTVNRATEKSVKTNGPLKQKQTTFSTKKITEKTVKAKSSVPASDDTYPEIEKFFPFNPLDFENFDLPEEHQIARLPLSGVPLMILDEERELEQLLHVGPPSPLKMPPLLWESNLLQSPSSILSTLDVELPPVCCDLDI
What is the function of this protein?
Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair.  Probably acts by blocking the action of key proteins.  During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.  At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1.  Its function is however not limited to a blocking activity, since it is required to activate ESPL1.  Negatively regulates the transcriptional activity and related apoptosis activity of TP53.  The negative regulation of TP53 may explain the strong transforming capability of the protein when it is overexpressed.  May also play a role in DNA repair via its interaction with Ku, possibly by connecting DNA damage-response pathways with sister chromatid separation (By similarity).
What are the official names of this protein?
Securin, Pituitary tumor-transforming gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the securin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AHL25_ARATH
Sequence: MSSYMHPLLGQELHLQRPEDSRTPPDQNNMELNRSEADEAKAETTPTGGATSSATASGSSSGRRPRGRPAGSKNKPKPPTIITRDSPNVLRSHVLEVTSGSDISEAVSTYATRRGCGVCIISGTGAVTNVTIRQPAAPAGGGVITLHGRFDILSLTGTALPPPAPPGAGGLTVYLAGGQGQVVGGNVAGSLIASGPVVLMAASFANAVYDRLPIEEEETPPPRTTGVQQQQPEASQSSEVTGSGAQACESNLQGGNGGGGVAFYNLGMNMNNFQFSGGDIYGMSGGSGGGGGGATRPAF
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity).  Binds the DNA sequence GNFEI (GA-negative feedback element I) in the GA3OX1 promoter.  Binding to GNFEI sequence is required for GA-negative feedback regulation of GA3OX1.
What are the official names of this protein?
AT-hook motif nuclear-localized protein 25, AT-hook protein of GA feedback 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNME_PSYCK
Sequence: MALAAPESSKNLGLSSLPTIAAIATPLGRGGVGVIRLSGTHAYSIACTLTGKSAFKPRMASFCRFYQADGTVIDEGLVLYFKGPHSFTGEDVIELQGHGGMILQNQLLARVFELGAKQASAGEFSYRAFDNDKLDLVQAEAIADAIDATSAAAASSAIRSLSGEFSQKINQLLEQLIHLRLHVEAAIDFPDEEDVDFLSDGVIQGKLEQTQEKIQQVLATAKQGQLLRDGIHVVLAGRPNAGKSSLLNRLAGQERAIVTDVAGTTRDTLQETVVLNGLTLHLTDTAGLRETEDTVERIGIERARTAIAQADMLLMVYDVTRDLEEESTPLQLAEQLFGELPEAKRLLIIANKSDLLNNNSSKEITSISQQEIHNRGYEQVNVSCETGAGIDDLVETLCAKVGFHPPENSLIARTRHLDALRRTAEYLAEAHEQLTVFKAGELVAESLRQAQHSLGEITGEFSADDLLGKIFGSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_PAEAT
Sequence: MSDAQQITLIVDGEETKVTEGTTGAELFFERRDVVVARVNGVLKDLDQVLTEGADVEGVTIDSPDGLNVLRHSTAHVMAQAVQQLRPEAKLGIGPYITDGFYFDFDVADPFTPEDLRTLEKMMQKIINQNQKFVRRVVTEEEAREAMANEPYKLELLGKKNDASDAAEGVNVEVGAGDITIYDNVDRKSGESIWCDLCRGPHLQNTKIISNAFALTRSSAAYWLGNQNNQQLQRIYGTAWPTKEALKAYQERIAEAERRDHRKLGVELDLFSFPDELGSGLPVFHPKGGIIRKAMEDYSRQRHVDAGYEFVYTPHITKGHLYEVSGHLDWYKDGMFPAMQVDAEFNEDGSVRKPAQDYYLKPMNCPMHNLIFRSRGRSYRELPLRLFEFGSVYRYEKSGVVHGLTRVRGMTQDDAHIYCTREQMKDELTTTLNFVLGLLKDYGLDDFYLELSTKNEEKFVGDDAAWEEATRTLSEVAEASGLHLVPDPGGAAFYGPKISVQAKDALGRTWQMSTIQLDFNLPERFELEYQAADGTRQRPVMIHRALFGSVERFMGVLTEHYAGAFPAWLAPVQVVGIPVAETFNDYMFDVVGQLKAAGIRAEVDISSDRFPKKIRTASKDKIPFVLIAGGEDAEAGAVSFRFRDGSQDNGVPVAEAVRRIVDAVKNRES
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLSO_ASFWA
Sequence: MLHWGPKYWRALHLYAIFFSDAPGWKEKYEAIQWILNFIESLPCTRCRHHAFSYLTKNPLTLNNSEDFQYWTFAFHNNVNNRLNKKIISWSEYKNIYEQSILKTIEYGKTDFIGAWSSL
What is the function of this protein?
FAD-dependent sulfhydryl oxidase that catalyzes the formation of disulfide bonds in viral proteins produced in the cell cytoplasm (By similarity).  Involved in virion maturation (By similarity).
What are the official names of this protein?
FAD-linked sulfhydryl oxidase, p14.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B119L family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: ERR3_RAT
Sequence: MDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV
What is the function of this protein?
Orphan receptor that acts as transcription activator in the absence of bound ligand.  Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements.  Induces the expression of PERM1 in the skeletal muscle (By similarity).
What are the official names of this protein?
Estrogen-related receptor gamma, Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECO_STACT
Sequence: MLMKQKGIIIKSVDYGESDKIITILNENGAKVPLMVKRAKKSKTGLQANTQLFVHGLFIYAKLRGLGILNSIDVINQNYQLRLDIYDSSFAALCAEIIDKSMEDEEISNFNFKLLEFCLNRIKEKDSAQLMSIIVLLKKMPSFGFSIDFDKCSISEENDQSKLIAFSFKYHGVISEQYIDRDPHAINISNKTLYLMDILQKLPIDNMNHLNIHQNILNEMSDLLIMLYREYSGIFFKSQKLINQLKRLEAK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PSBF_CROS5
Sequence: MVNNTSNQPTSYPIFTVRWLAVHTLAVPTVFFVGAIAAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: LOLD1_EPIUN
Sequence: MATVVREAFENHVKLVESRNSPGHVLASSEASFFVADLNDIVRKWAAWKKALPDVTPFFAVKSSYDRRLIQTLATCGAGFDCASVEEIELILSLGIGAERIVFTHPCKPVSSLGLCRKLGITLITFDNECELRKLHHHYPEAQTVLRVFADDPTNADPLGTKFGAAREDIDGLVRLVKELNMKLAGASFHAAPSVAVDAAAYVRGIRDAAEVFARARRVGLNPTVLDIGGGYTDSTFQQIAGAVRPAIAECFKSQVVEGRLRILAEPGTLFSCSPFYLAVKVVARRRNAAAFGNEPATRLYINDGIYSNFMMRFIVNMTFSPVAVIRKGVWYDQTEQTMRREACSLWGRSCDSNDCINRDCRLDPEVGVGDWLVFKDMGAYTTVCNTTFNGFTSSNHTIYIEPTQVDKAQSTFEQLELAI
What is the function of this protein?
Amino acid decarboxylase; part of the gene cluster that mediates the biosynthesis of loline alkaloids, potent insecticidal agents composed of a pyrrolizidine ring system and an uncommon ether bridge linking carbons 2 and 7 (PubMed:15654104).  Lolines are structurally differentiated by the various modifications of the L-amino group and include norloline, loline, N-methylloline, N-acetylloline, N-acetylnorloline, and N-formylloline (PubMed:15861432, PubMed:25531527).  The first committed step is the condensation of O-acetyl-L-homoserine (derived from L-aspartic acid) and L-proline, probably catalyzed by the gamma-type pyridoxal 5'-phosphate(PLP)-dependent enzyme lolC, to give the diamino diacid, NACPP (PubMed:15861432, PubMed:16755627).  Ensuing cyclization, decarboxylation, and acetylation steps yield 1-exo-acetamidopyrrolizidine (AcAP)(PubMed:24374065).  LolO is required for installation of the ether bridge upon the pathway intermediate, 1-exo-acetamidopyrrolizidine (AcAP) (PubMed:29537853).  In sequential 2-oxoglutarate- and O(2)-consuming steps, lolO removes hydrogens from C2 and C7 of AcAP to form both carbon-oxygen bonds in N-acetylnorloline (NANL), the precursor to all other lolines (PubMed:24374065, PubMed:29537853).  The enzymes lolD, lolE, lolF and lolT have also been proposed to be involved in the ether-bridge installation (PubMed:15654104).  Further processing of the exocyclic moiety of NANL by fungal N-acetamidase (LolN), methyltransferase (LolM), and cytochrome P450 (LolP) enzymes, with occasional involvement of a plant acetyltransferase, generates the other known lolines (PubMed:25531527, PubMed:18655839).  LolN transforms NANL to norlonine which is monomethylated and dimethylated to respectively lonine and N-methyllonine (NML) by lolM (PubMed:25531527).  LolP catalyzes hydroxylation of the methyl group in N-methylloline (NML) and further oxygenation to N-formylloline (NFL) (PubMed:18655839).  A plant acetyltransferase is responsible for the acetylation of loline to form N-acetylloline (NAL) (PubMed:25531527).  LolA might interact with aspartate kinase to prevent feedback inhibition of its activity by these end products and thereby promote production of L-homoserine from L-aspartate (PubMed:15654104).
What are the official names of this protein?
Amino acid decarboxylase lolD1, Loline biosynthesis cluster 1 protein D.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Protein: ATRH_ASPOR
Sequence: MALPREERSLHGHANIHVNQTTGPAIDKAESSDTIGADSEDGIEQEGQAKITTLARTLSRISQTNSGTEGLNPFLNTSDPELDPNSDQFNSRKWTKTLLHITSRDPERYPRRTAGVSFRNLNAFGYGTAADYQATVSNVWLKAAGWLRGLFGNGNKVRIDILRNFEGFVNSGEMLVVLGRPGSGCSTFLKTIAGETHGLWLDKGTDIQYQGISWDEMHSRFRGEVMYQAETEIHFPQLTAGDTLLFAAKARAPANRLPGVSRDQYATHMRDVVMAMLGLTHTMNTLVGNEFIRGVSGGERKRVSIAETTLCGSPLQCWDNSTRGLDSSTALEFVKNLRLSTDYTGSTAIVAIYQASQAIYDVFDKVIVLYEGRQIYFGRARDAKRFFIEMGFDCPERQTTGDFLTSLTSPTERLVRKGYEHLVPRTPDEFAARWRDSLERKQLLADIEAFQNEFPLGGSKKEEFSRSRAAEKAKNTRASSPYTLSYSMQIKLCLQRGFLRLKGDMSMTLSTVIGNSILALIISSVFYNLNETTDSYFSRGALLFFAILLNAFASALEMLTLWQQRPIVEKHDKYALYHPSAEAISSLIVDLPAKAPVSIVFNLILYFMTNLRRTPGHFFVFYLFSVTTTLTMSNVFRWIAAVSRSLAQAEVPASIFMMILMIYTGFTIPVRDMHPWFRWLNYINPIAYSFESLMINEFAGRKFHCATYVPSGPGYDNAPLDSKICSGKGAVAGQDYIDGDRYLEVAFEYYPSHLWRNFGILLGFLFFSLVAYIVASELVRAKPSKGEILVFPRGKIPAFAKKVHREADPEDVLTSEKLKVGSEQDDHVGAIVKQTSIFHWQDVCYDIKIKGQDRRILDHVDGWVKPGTLTALMGVTGAGKTSLLDVLANRVTMGVITGEMLVDGRMRDDSFQRKTGYVQQQDLHLETSTVREALIFSALLRQPASTPRKEKLAYVEEVIKMLNMEEYAEAVVGVLGEGLNVEQRKRLTIGVEIAAKPDLLLFFDEPTSGLDSQTAWSICSLMRKLVDHGQAILCTIHQPSAILMQQFDRLLFLAKGGKTVYFGDLGPNMRTLIKYFEDKGSPKCPPNANPAEWMLEVIGAAPGSRADQDWSDVWKHSRERAQVQQELLQMKQELLQRPQPPRTAGYGEFAMPLWAQFFICLQRVFQQYWRCPSYIYAKAAMCIIPPLFIGFTFWREPTSIQGMQNEMFSIFMLLVIFPNLVQQMMPYFAMQRSLYEVRERPSKAYSWKAFMLASIVVELPWNMLMAVPAYFCWYYPIGLFRNAYPTDSVTERGGTMFLLVLIFMLFTSTFSSMMIAGIDHPETASNIAQLMFSMCLIFCGVLASPDVLPRFWIFMWRASPFSYLVGSVLAVGIAGAPVHCSDIEVLHIPPPGGQNCSGYLEAFTTMAKSTLLNPEADSDCQVCSLSTTDQFLAGVHIKYSELWRNVGILFVYIVFNTVAAVFLYWLVRVPKKRALKKAKKE
What is the function of this protein?
Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility.
What are the official names of this protein?
ABC multidrug transporter atrH.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TVB69_HUMAN
Sequence: MSIGLLCCVAFSLLWAGPVNAGVTQTPKFHILKTGQSMTLQCAQDMNHGYLSWYRQDPGMGLRRIHYSVAAGITDKGEVPDGYNVSRSNTEDFPLRLESAAPSQTSVYFCASSY
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 6-9.
What are the subcellular locations of this protein?
Cell membrane.
Protein: CATV_NPVAP
Sequence: MNKIVLYLLVYGATLGAAYDLLKAPSYFEEFLHKFNKNYSSESEKLRRFKIFQHNLEEIINKNQNDTSAQYEINKFSDLSKDETISKYTGLSLPLQKQNFCEVVVLDRPPDKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHDQLINLSEQQLIDCDFVDVGCDGGLLHTAYEAVMNMGGIQAENDYPYEANNGPCRVNAAKFVVRVKKCYRYVTLFEEKLKDLLRIVGPIPVAIDASDIVGYKRGIIRYCENHGLNHAVLLVGYGVENGIPFWILKNTWGADWGEQGYFRVQQNINACGIKNELPSSAEIY
What is the function of this protein?
Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus.  May participate in the degradation of foreign protein expressed by the baculovirus system (By similarity).
What are the official names of this protein?
Viral cathepsin, V-cath, Cysteine proteinase, CP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: XYNA_PHACH
Sequence: MKLSASFAALALLLPFVQAQSPVWGQCGGIGWTGPTTCTAGNVCQEYSAYYSQCIPASQATSVTSVSTAPNPPPTSHTSTSSAPSGASTSTAKLNTLAKAKGKLYFGTATDNGELSDTAYTAILDDNTMFGQITPANSMKWDATEPQQGQFTFSGGDQIANLAKSNGMLLRGHNCVWYNQLPSWVSNGKFTAAQLTSIIQNHCSTLVTHYKGQVYAWDVVNEPFNDDGSWRTDVFYNTLGTSYVQIALEAARAADPDAKLYINEYNIEYAGAKATSLLNLVKTLKAASVPLDGIGFQSHFIVGQVPTGLQSQLTTFAAQGVEVAITELDIRMTLPSTPALLAQQKTDYSNVIKACASVEACVGVTVWDWTDKYSWVPNTFSGQGAACPWDQNFVRKPAYDGIAIGFGN
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase A, Xylanase A, 1,4-beta-D-xylan xylanohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.