PharMolix/UniProtQA huggingface dataset:
Protein: SUN2_DICDI
Sequence: MIINKKYILFILLLLFITSCTIVFSQQQQQQTEQSEQTEQAINNDVNNSINDIFENDSSKQLRQPQQQHTIVDDGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNPIDNKDILGLKKLALLKQFEEQKSKSENDINNDIVILNLENDNPNQIIETTTTTLNNSNDNKNNIIDDNQDEKLNENIKEDKNEIKNEIKNENQEKDKGIIDVEKDENQPNIEEKGKEKQNLLEKGIENENQNENQIQIEKEKEIEIEIEKEKEKENKELIEESKTEKDNQQKENKENTNEINVTVVEEPEQPQPQQQNQQEQQEQQQQEHKEEQQQQEQQQQEQQTQQEQQTHQQQQEHQETQKNSSEETKTQSPIQVNTTDVNNEIELKNEGDNNSQLNDSSIPITSPLTNDNDTLKTTKEDSNNNNKNEVINNQTPLIDEKNHQHNYEGNNRNGDDVSIISNIPKTNKAPETQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVVLTPNDLPDKFNYASSECGANVLQTNKEAWEVSSILASSRDRYLLNECNKSQWFVVELCEEIGVQIIELANFEFFSSMFKDFIVLGSNRYPAQSWHYLGQFTAENSRKQQYFVLKEKAWYKYLKVKILSHYGDQLYCPISSFKVYGSTMVDDLKNQVDINISELEKFQRDLSSIPYPMEIGSDTSYSTTTSTTSSSSTSSSYPSSKTKSSNSEYPSWERIQSFSEKLRKNVEQQLIQPPSVLNTNDNNNNNNNNNNNNNNNNNNNNNNNNNEEQFIYYETNGNGGPPSTSTSTSSSSSQNHQARTPQSVFKTLADKIKAIEFNQSIGNKFMEKLERYYSEEIKNLKFDVSEFLNDIIKLGNSLDEKLKDHRKYDDNKFKETSKEIKILKEKIEKLEEQKSADRNFYLVVTLVSLLIGLLLKPLFTSSSSSSNKSYPNSMPNSPTYLNSGSNNYNNNGIINSSGGSGGGGGNLQNSSFIGINGQLNFSDDNISAFLNSSCSNFGLNNNNNNNNGINNNNNNSNSNSNNNSINNGSININSNNSLQQRIHHNKYIHQRRNSSPLVGVQLESFFSPNAIPPTIPIVPQDDNNINYNYNNNNNTNNINNNYNYNNNNNNNNNNNNNNNNNNNNNSDNYNNNNNSNNNVNSPSSPTPSSIILSPKFITSIPKNINYYNNGGSGSHLKNRFSRQASESVLSQNHYQINHQNHSLNGVTTNINNNNSNSNGNSNGNSNNMTNGLPPVSMPSSSSHDNLLLHRGNNQSKKYKRRSHL
What are the official names of this protein?
SUN domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: CH10_CUPNH
Sequence: MNLRPLHDRVIVKRLDNETKTASGIVIPDNAAEKPDQGEVLAIGPGKKDDKGNNIALDVKVGDRVLFGKYAGQAVKVEGQELLVMREEDIMAVVNK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP45_YEAST
Sequence: MFSNRLPPPKHSQGRVSTALSSDRVEPAILTDQIAKNVKLDDFIPKRQSNFELSVPLPTKAEIQECTARTKSYIQRLVNAKLANSNNRASSRYVTETHQAPANLLLNNSHHIEVVSKQMDPLLPRFVGKKARKVVAPTENDEVVPVLHMDGSNDRGEADPNEWKIPAAVSNWKNPNGYTVALERRVGKALDNENNTINDGFMKLSEALENADKKARQEIRSKMELKRLAMEQEMLAKESKLKELSQRARYHNGTPQTGAIVKPKKQTSTVARLKELAYSQGRDVSEKIILGAAKRSEQPDLQYDSRFFTRGANASAKRHEDQVYDNPLFVQQDIESIYKTNYEKLDEAVNVKSEGASGSHGPIQFTKAESDDKSDNYGA
What is the function of this protein?
Involved in pre-mRNA splicing.  Associated with the spliceosome throughout the splicing reactions, until after the second catalytic step.
What are the official names of this protein?
Pre-mRNA-processing protein 45.
What is the protein family that this protein belongs to?
Belongs to the SNW family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA2B1_BOTPA
Sequence: DLWQFGKMILKVAGKLPFPYYGAYGCYCGWGGRGKPKDPTDRCCFVHDCC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2).  In vitro, shows anticoagulant activity and induces cytotoxicity when tested on C2C12 myoblasts/myotubes.  In vivo, when tested on mice, induces myotoxicity (intramuscular injection), edema (injection in the subplantar region) and lethality.  Also induces neurotoxic effect on mouse neuromuscular preparations and has bactericidal activity on the Gram-negative bacteria E. coli (ATCC29648) and the Gram-positive S. aureus (ATCC 25923).  The catalytic and anticoagulant activities of BnpTX-I are higher than those of BnpTX-II.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 BnpTX-1, BnPTx-I, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TAM_ECOUT
Sequence: MSDWNPSLYLHFAAERSRPAVELLARVSLENIEYIADLGCGPGNSTALLHQRWPAARITGIDSSPAMIAEARSALPDCLFVEADIRNWQPEQALDLIFANASLQWLPDHYELFPHLVSLLSPLGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQHFLTRYHQMLEEQYPLQENGQILLAFPRLFIVARRTE
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_ANASK
Sequence: METSLRRAAAPAGAVAERTVLRNGGTVRDAVAVEEPLEIRVDGDRLATTMRTPGADGDLALGFLFAEGIISGVEDVGTVIHCGRPGEEGYGNVMDVRSAAGMRIDPERILEGRRFVPVSAACGVCGRLSIDHLMERIRTLPAGEPVAPALVAAGMEILARSQPVFERTGGLHAAVLVGRDGAPIASAEDVGRHNAVDKVVGAALRAGRVGPRAAAGPAPALLAVSGRAGFEIVQKAAAAGVPVIASVSAPSSLAVDLARAAGVTLCGFVRGERMNVYANGERLGLTGP
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_GEOMG
Sequence: MKFDILTLFPAMFEGPLTESIIRRAVEKGLLDIRLHQIRDFATDRHKVVDDAPYGGGDGMVMKVEPIAACLEAVKAERPKARVLLTSPRGRLFDNAAARELAQEQEVIIICGRYEGIDERVRELFVEDEFSIGDFVLTGGELAAMVMIDATVRFVPGVLGSPGSAETDTFSDGLLEYPHYTRPAEFRGHSVPAVLLSGNHAEVARWRRRKALEETIRSRPDLLEKAVLDSDDRRYLLELEEGASK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCH_HUMAN
Sequence: MAKMNLSSYILILTFSLFSQGILLSASKSIRNLDDDMVFNTFRLGKGFQKEDTAEKSVIAPSLEQYKNDESSFMNEEENKVSKNTGSKHNFLNHGLPLNLAIKPYLALKGSVAFPAENGVQNTESTQEKREIGDEENSAKFPIGRRDFDMLRCMLGRVYRPCWQV
What is the function of this protein?
MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal.  May also have a role in spermatocyte differentiation.
What are the official names of this protein?
Pro-MCH.
What is the protein family that this protein belongs to?
Belongs to the melanin-concentrating hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_BRUAB
Sequence: MDIRAAEISAILKEQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIRGMALNLESDNVGVVIFGADRDIKEGDVVKRTGAIVDVPVGPELLGRVVDALGNPIDGKGPIKAKERRRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPVGRGQRELVIGDRQTGKTAIILDTFLNQKPIHDNGPDKDKLYCVYVAVGQKRSTVAQFVKVLEERGALEYSIVVAATASDPAPMQYLAPFAGCAMGEYFRDNGQHALIGYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDENGAGSLTALPVIETQGNDVSAFIPTNVISITDGQIFLETNLFYQGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKGELAQYREMAAFAQFGSDLDAATQRLLNRGARLTELLKQPQFSPLKTEEQVAVIYAGVNGYLDKLAVNQVGKFEEGLLASLRTEHKDVLEGIRNEKALTDDLKAKLKAAIDAFAKSFV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNB_SALA4
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIVAVIHTEKERESAEPEELIEPFLTRFVGKVQGKNDRLSIVPDHPLLKDAIPCRAARGVQHEFKEGDWAVAEMRRHPLKGDRSFYADLTQYITFADDHFVPWWVTLARHNLEKEAPNGVATEMLDEGLERQDLTALNFVTIDSASTEDMDDALYAEELADGRLQLTVAIADPTAWIAEGSKLDNAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPALACRMIIAADGTIDDDIAFFAATIESKAKLAYDNVSDWLENNGTWQPDNEGIAQQIRLLHRICLSRSEWRHHHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEESMIAANLCAARVLRDKLGFGIYNVHTGFDPANADALAALLKTHGLHVDAEEVLTLEGFCKLRRELDAQPSGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGEAIARPQEDITQQMAERRRLNRMAERDVGDWLYARFLNDKAGTNTRFAAEIIDVSRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPAA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF4_PHAVU
Sequence: MSILKKRSKEVLIYSITESKISNIFSALIIFLGSLGLLLVAISSYLGMDLFLFSEEISNFPFIPQGATMAFYGIGGLFISFYLWWILLWNIGGGFDIFDKKNKKVCFIRWGFPGKNRRIILKIPMNEIQSIRIIAGVQERGILTRTLTYESIVYMETIEQGFITLTRIEDNLTPPEIANKAGELAFFLGVPLLY
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: BGLA_BACSU
Sequence: MGNMPKDFLWGGALAAHQFEGGWNQGGKGPSVVDVMTAGAHGVPRKITDTIEENEFYPNHEAIDFYHRYKEDIALFAEMGLKCLRTSIGWSRIFPKGDEAEPNEAGLQFYDDVFDELLKHGIEPVITLSHFEMPLHLAREYGGFRNRKVVDFFVNFAEACFTRYKDKVKYWMTFNEINNQMDVNNPLFLWTNSGVVVGENENAKEVMYQTAHHELVASALAVAKGKDINPEFQIGAMVSHVPIYPFSSNPEDVMLAEEEMRQRYFFPDVQVRGYYPSYALKEFEREGYNITFEDGDDEILRNGTVDYLGFSYYMSTTVKSDVKNDNTGDIVNGGLPNGVENPYITSSDWGWAIDPTGLRYTLNRFYDRYQIPLFIVENGFGAVDTLEEDGKVHDPERIQYLKSHIEALKKAVTYDGVDLIGYTPWGIIDIVSFTTGEMKKRYGMIYVDRDNEGNGSMKRYKKDSFEWYKNVIQTNGEEL
What is the function of this protein?
Catalyzes the hydrolysis of aryl-phospho-beta-D-glucosides such as 4-methylumbelliferyl-phospho-beta-D-glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin.  Plays a major role in the utilization of arbutin or salicin as the sole carbon source.  BglA and BglH are the major proteins contributing to hydrolysis of MUG-P by extracts of late-exponential-phase or stationary-phase B. subtilis cells.
What are the official names of this protein?
Aryl-phospho-beta-D-glucosidase BglA, 6-phospho-beta-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: DXS_AGRVS
Sequence: MTSKPNTPLLDQVVFPSDLRKIEDKDMPQVARELRDEMIDAVSVTGGHLGAGLGVVELTLAIHKVFNTPEDRLIFDVGHQCYPHKILTGRRERIRTLRQEHGLSGFTKRAESEYDPFGAAHSSTSISAGLGMAVAAELGQTDRKVIAVIGDGAMSAGMAFEALNNAGALDARLIVILNDNDMSIAPPTGAMSAYLARLASGRTYMGMREIGKKLTAYLGKNIDRAITRAVEHARGYVTGGTMFEEMGFYHIGPIDGHSFDHLLPVLRNVRDNAKGPVLIHVVTQKGKGYAPAEAAADKYHGVNTFDVITGTQAKAKPNAPSYTAVFADALVEEARLDDKIVGITAAMPSGTGLDKLQNLFPERTFDVGIAEQHAVTFAAGLAAEGYKPFCALYSTFLQRGYDQVVHDVAIQGLPVRFPIDRAGFVGADGPTHAGSFDTGFLASLPGFVVMAAADEAELKHMVRTAAAYDEGPISFRYPRGEGVGVQMPERGEILPIGKGRIIKEGSKVALLSFGTRLAECLVAAEDLDAAGLPTTVADARFAKPLDLDLIRQLARHHAVLITVEEGAVGGFGSQVLHMLANEGLLDHGLKVRSLVLPDLWMDQAKPDVMYEKAGLDAKGIVSTVFTALSRDALAQDSLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: ATPF_SHEAM
Sequence: MNINATLIGQTVAFIIFVWFCMKYVWPPLMNAIEERQKRIADGLANADRAAKDLELAQAKATEQLKEAKATANEIIESANKRKAQIVEEAKAEADAERARIIAQGKAEIEAERNRVKEELRKQVATLALAGAEKILERSIDAAAHSDIVEKLVAEI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TAL2_YEAST
Sequence: MSEPSEKKQKVATSSLEQLKKAGTHVVADSGDFEAISKYEPQDSTTNPSLILAASKLEKYARFIDAAVEYGRKHGKTDHEKIENAMDKILVEFGTQILKVVPGRVSTEVDARLSFDKKATVKKALHIIKLYKDAGVPKERVLIKIASTWEGIQAARELEVKHGIHCNMTLLFSFTQAVACAEANVTLISPFVGRIMDFYKALSGKDYTAETDPGVLSVKKIYSYYKRHGYATEVMAASFRNLDELKALAGIDNMTLPLNLLEQLYESTDPIENKLNSESAKEEGVEKVSFINDEPHFRYVLNEDQMATEKLSDGIRKFSADIEALYKLVEEKM
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase NQM1, Non-quiescent mutant protein 1.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
Protein: RPOA_DELAS
Sequence: MQTNLLKPKTINVEQLGHNRAKVVLEPFERGYGHTLGNALRRVLLSSMVGYAATEVTIAGVLHEYSSIDGVQEDVVNILLNLKGVVFKLHNRDEVTLSLRKDGEGVVTARDIQTPHDVEIINPDHVIANLSQGGKLDMQIKVEKGRGYVPGNVRRYGDESTKSIGRIVLDASFSPVKRVSYAVESARVEQRTDLDKLVVEIETNGAITAEDAVRASAKILVEQLAVFAQLDGGDIASVFDAPAGGRGAATAFDPILLRPVDELELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLEKR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MCBF_ECOLX
Sequence: MTIPLLEINSLSFSYKVNLPPVFNNLSLKIEQGELIGLLGENPAGKTTLFNLIRGGVSNYEGTLKRNFSGGELVSLPQVINLSGTLRNEEVLDLICCFNKLTKKQAWTDVNHKWNDNFFIRYDKIRRKRTYTVSYGEKRWLIISLMVTLCKNARLFLLDEPTVGIDIQYRMMLWELINKITADGKTVFFSTHIFDELTRDKIPFYMLSKNSINRYSDMSDFIQSNNETTQKRHLLKKLWEQETDTWI
What is the function of this protein?
Together with two further proteins McbE and McbG this protein causes immunity to the peptide antibiotic microcin B17, which inhibits DNA replication in enterobacteriaceae.  Immunity is determined by two different mechanisms.  McbE is involved in the production of extracellular MccB17 and, in a complex with mcbf it also serves as 'pump' for the export of active MccB17 from the cytoplasm to the periplasmic space.
What are the official names of this protein?
Protein McbF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: PYRF_CELJU
Sequence: MSFIEKLKNAWVSNNSLLCIGLDPDTEKFPDLFKTMAKPEAVFAFNKAIIDATHDLVCAYKPQIAYFSAEAAETSLEQTIAYIKTQYPHIPVILDAKRGDIGSTAQKYAAEAFERYQADAVTVNPYLGLDSITPFTAYRERGTILLCRTSNSGAADLQDLSVDGIPLYQKVAITARDHWNSHNNCLLVVGATWPEQMAAIRQLVGDMPFLVPGVGAQGGDVNAMVKAGKTADGNGLIISSSRAVLYASNGDDFAQAARAVALSLRQQINVARA
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: FXL15_DANRE
Sequence: MDQKPDERVQSHRCELLDLPWEDVLVSHVFCHLPLRLLVSLQRVSKSFRSLIQVYLDNCRTFDPAQTGPHIPREAFCSILRHNQVLQHLSVTNCSDWITDTDLLPVIGQNQQLQHVDLRGCAQLSRRALVAVSLSCPRLQHLSLAHCEWVDSLALRSLADHCPMLRSLDLTACRQLKDPAVCYLAGKCPELRALSVAVNANITDTAVEEVAKKCREMERLDLTGCLRVRNEAIRTLAEYCPKLQSLKVNHCHNVTESSLGVLRRRNVEIDVEPPLQRALVLLQDVVGFAPFINLQI
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Acts as a positive regulator of the BMP signaling pathway (By similarity).  Required for dorsal/ventral pattern formation.
What are the official names of this protein?
F-box/LRR-repeat protein 15.
What is the protein family that this protein belongs to?
Belongs to the FBXL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_SHISS
Sequence: MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_ORITB
Sequence: MNIHEYQAKEILSKYNVPIQPGIAILKYEDIDYAIDSLATDTFVIKAQIHAGGRKIGGGIKISNDKNEAKNLAKNMWGMNLVTPQTGPKGQKVQRIYIESAAKIKLELYLGAVIDRSNHCITFMASSAGGINIEEVAHTNPDKIIKVKINILTGIQPFHSRKIIFQLGLTGDLAKQMAKIMSAVYSMLINTDATQVEINPLIITLDDKLIALDAKINFDDSALFRQPLIQGMRDEDEEDHLELRATKADLSYVRMNGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGSADKKRVAEALKIISSDQNVKGILINIFGGIMRCDIIAEGVLAAAKEINLSIPLVVRLAGTNFELGKEILSNSKLQIVAANDLDDAARKIVEAVS
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: XGAT4_POPTR
Sequence: MTMHEKMKLPSCSCSAFKCGKKDRWLNMERPIPFLLIGLTTILSVFILYTLNPLKFVIEHNIDQKLLLIKPHKEEDKCDLFNGNWVPDFEGSIYTNSSCATIPTSKNCFRNGRKDQDFLNWRWKPERCDLPRFDATAYLDIVRGKTLAFIGDSVARNHIESLLCLLSQKEVPVDAYLDSEDRNRIWHFPVHNFTLKMLWTKFLVHGEERVINGSSSGIFDLYLDKVDENWARDLHSLDYVVISDAHWFFRQVYLHRGSNVVACVYCNEANVTDRGVAFALRMAFRAAFSQINHCNKCKGIVTLLRTFSPSHFENGFWNTGGSCNRTSPYNDQKINFGAYEWEIRSMQVEEIERAEKRGKKGKSFGVLDVTMAMLMRPDGHPGAFWGNQWMKGYNDCVHWCLPGPIDVWNDLLLAVLRRLD
What is the function of this protein?
Xyloglucan acetyltransferase that catalyzes the acetylation of fucosylated Gal residues on xyloglucan side chains (PubMed:30083810).  Predominantly catalyze 6-O-monoacetylation of Gal residues in the Fuc-Gal-Xyl trisaccharide side chains of xyloglucan oligomers (PubMed:30083810).
What are the official names of this protein?
Xyloglucan O-acetyltransferase 4, PtrXGOAT4.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PLSY_DESVH
Sequence: MGSLLWLAVAYVMGSIPFGLLFAKMFCGTDPRTGGSRNVGATNVARLCGTKVGVLTLVCDALKGAIPVAVALSISDSTVFHSLTALAALLGHLYSCFLSFKGGKAVATTVGVFLPLAFWPLVLSGIACLAVIWRSGFVSLGSLTLVTAMPAMLLLGGHWKLVPLALVVMVLVYWSHRENIGRLSRGEEKPWQKKHHDAAQGTDAGAAPEAAADAAHAGTVDCGCDCGCDAHKPSTEAAPSQETSDASAHGAEAPVAADEGDKRENEEHDNAPEASAAESKPEDKPAGKTVGKPASRSVAKPASKSAGKTGGKAADKSAGKSGKSSGQ
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SUCB1_COLLI
Sequence: RRLSLHEYLSMGLLQEAGISVPHGVVARTPDEAYKIAKEIGSKDLVIKAQVLAGGRGKGTFEGGLKGGVKIVFSPEEAKAVSSRMIGKKLFTKQTGEKGRICNQVFVCERRYPRREYYFAITMERSFQGPVLIGSSQGGVNIEDVAAENPDAIIKEPIDIVEGIKKEQAVRLAQKMGFPSNLVDEAAENMIKLYNLFLKYDATMIEINPMVEDASGVVMCMDAKINFDSNSAYRQKKIFDMQDWTQEDERDRQAAKADLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVVAVKDLDLKIPVVVRLQGTRVDDAKALITASGLKILACDDLDEAAKMVVKLSEIVTLAKQAHLDVKFQLPI
What is the function of this protein?
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, ATP-specific succinyl-CoA synthetase subunit beta, A-SCS, Succinyl-CoA synthetase beta-A chain, SCS-betaA.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DUG2_YEAST
Sequence: MYDSRGVALHSELIHRWNHAFSILSIVAFPKKRLLFAGSQDSKILVFDLPTYNLIHTIRLGESQEETHTRSSVLCLTGSEDENFLFSGGADSLVRIWSIGEKTIRDDFLPVTEIATVYSVTDIGDIFSLAYLDSLETIVFGCQNASLLYVENLIQKIEKKSSDGVENINKLPHRRYDKFFDSLGPTGYSSNSLSQTSLTSLQENCGAAIIEVPSENIIKYAHYGFIYSINKLCPRFNQLLEKSSRTSGAEHIISSAGDGISKLWEFSKDKGQNTVKISLINDKIDNEDSVISQTIEFPFLYCGLTDGIIKIWDLNTQQIISTLKTKHESDVISISVYMDHVFAIDESGITHFYQNQVNHWNPQQGKILSSEIFSKSNAGSVSLLTGGSDGSLTLWDITSLLSAVPLSSNSPINASSTLQTTNLWAAYQSASLNNEEMLNTLRELISFQTVSQSKDTTNTLSLRRCAIYLQQLFLKFGATNSQLFPLPDGGNPVVFAYFQGNGKVSQVKGAKKKRILWYGHYDVISSGNTFNWNTDPFTLTCENGYLKGRGVSDNKGPLVSAIHSVAYLFQQGELVNDVVFLVEGSEEIGSASLKQVCEKYHDIIGKDIDWILLSNSTWVDQEHPCLNYGLRGVINAQIKVWSDKPDGHSGLNGGVYDEPMVNLVKIVSKLQNEQNEIMIPNFYSPLKDLTEEEYQRFQKITELANIDENTTVQDLITNWTKPSLSMTTVKFSGPGNITVIPKSVTMGISIRLVPEQSVEQVKRDLKAYLEESFKQLKSQNHLEIKVLNEAEGWLGDPTNHAYQILKDEITTAWDVEPLLVREGGSISCLRMLERIFDAPAVQIPCGQSTDNGHLANENLRIKNWSNLTEILSKVFNRL
What is the function of this protein?
Component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond.
What are the official names of this protein?
Probable di- and tripeptidase DUG2, Deficient in utilization of glutathione protein 2, GSH degradosomal complex subunit DUG2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.