PharMolix/UniProtQA huggingface dataset:
Protein: ADCL3_HUMAN
Sequence: MWDLALIFLAAACVFSLGVTLWVICSHFFTVHIPAAVGHPVKLRVLHCIFQLLLTWGMIFEKLRICSMPQFFCFMQDLPPLKYDPDVVVTDFRFGTIPVKLYQPKASTCTLKPGIVYYHGGGGVMGSLKTHHGICSRLCKESDSVVLAVGYRKLPKHKFPVPVRDCLVATIHFLKSLDAYGVDPARVVVCGDSFGGAIAAVVCQQLVDRPDLPRIRAQILIYAILQALDLQTPSFQQRKNIPLLTWSFICYFFFQNLDFSSSWQEVIMKGAHLPAEVWEKYRKWLGPENIPERFKERGYQLKPHEPMNEAAYLEVSVVLDVMCSPLIAEDDIVSQLPETCIVSCEYDALRDNSLLYKKRLEDLGVPVTWHHMEDGFHGVLRTIDMSFLHFPCSMRILSALVQFVKGL
What are the official names of this protein?
Arylacetamide deacetylase-like 3.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: ISCS_METTE
Sequence: MAIHNCEGENVSTENKAVYMDNSATTPVRKEVVEAMLPYMTENFGNPSSIYEIGKTSKHAINLARKKAADALGAEENEIYFTSGGTESDNWAIKGIAFANRDKGKHIITSSIEHHAVLHTCAWLEGQGFEVTYLPVDKYGMVSPDELRNAIRDDTILISIMFANNEIGTIQPIKEIGEIAKENQIYFHTDAVQAIGHVPIDVKKLNIDLLSLSGHEFEGPKGCGALYIRKGVKIDPLLHGGAQERKRRAGTENVPGIVGLGKATELATAEIEESNRTLLKLRDRLIEGLLKIPKTHLNGHPTQRLANNVNVTFEYIEGESLLLLLNAKGIYASTGSACNSSSLEPSHVLTACGVPHEIIHGSLRLSLGRMNTSEDVDRVLEVVPEIVQKLRNMSPLTPKEYRTL
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2632_SYNJB
Sequence: MYTLELLLKGNPAPIVVHQKEEEAANRAYQSIVNALQSGSPQSLELTCDRTGKKVFLLTGELCGVQMTSKSGSASPMGTRPGFLAQLQS
What are the official names of this protein?
UPF0367 protein CYB_2632.
What is the protein family that this protein belongs to?
Belongs to the UPF0367 family.
Protein: DNI2_SCHPO
Sequence: MERGTSKFSWIGLVARIYNYIPHPSIFSNAILGIAWLFLIFLCCSCLTKSSIFARLLRVKNETTTVDVGFFGVCDQAINSTSRVCHELRNWDQTTGGLAYETSRFAWLQVHPVLLAIVVVFSTLSIVLTILKYLAPAYIRQWSISCLTTSTAACLLLALQMALAHISANSYAVGMNLTGKATAKFGVAAAVFGWISSGFFLLFSLIHLGLWTIERNKQKLFEETSLSFSFITTKLRLIETQYFICKDY
What are the official names of this protein?
Delayed minus-nitrogen induction protein 2.
What is the protein family that this protein belongs to?
Belongs to the SUR7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RLMN_BURA4
Sequence: MTSETSVNLLDFDAEGLVAYCGSLGEKPFRAKQLQRWIHQYNAGDFDGMTDLAKSLREKLKGRASIVMPEIASDHVSADGTRKWLIDVGNGNAVETVFIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLSTAEIIGQLRMAEFALRASLGRAPGPNGKAERVVTNVVMMGMGEPLLNYNAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLGAELPVALAVSLHAPNDALRDELVPLNKKHPLRELMAACQRYLKVAPRDFITFEYCMLDGVNDTEAHARELLAVTRDVPCKFNLIPFNPFPESGLIRSKPEQIKRFAQVLIDAGVVTTVRKTRGDDIDAACGQLAGAVKDRTRLAERTGAAAKIIEVRAI
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUGS_BACSU
Sequence: MLILQLIAIFVLIGITAVFVAAEFAIVKIRGSKINQLIESGDSRALAAHKIISNLDEYLSACQLGITITALGLGWLGEPTFERFLHPLFTMTGIPEPFNHIVTFVVAFIIVTFLHVVMGELAPKTVSIQKAEAVSLWIAKPLIWFYKITYPFIKALNGSASFLVKLFGFHSVKEHQVVISEEELRLILSESYEKGEINQSEFRYVNKIFEFDNRVAREIMIPRTEIAVISLEQSLEEAIHHIINERYTRYPVIKDDKDHILGIINSKDMFKAYFLGQPIKLNQIMRPVIRVIESIPVQQLLIRMQKERIHMAILVDEYGGTAGLVTVEDIIEEIVGEIRDEYDQDETPHILKKGEHHYVMDGKALIDEVNDLLDIAIENEEIDTIAGWLLTQKMELKAGDVIHAEGCEFKILDAEDHHIRFVEIKKTDF
What are the official names of this protein?
UPF0053 protein YugS.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRF_TOLAT
Sequence: MTEPKVIVALDFAKKEEALSFVDQVTPSDCRLKIGKEMFTYYGPQFVEQLVKKGFDVFLDLKFHDIPTTVAKAVKASAEMGVWMVNVHASGGRKMMEAARSALLPYGDKAPLLIAVTVLTSMEQSDLADIGLDIPPFEQVLRLATLTQQAGLDGVVCSAQEASVLKSRLGNEFKLITPGIRLDVSTKVDDQSRVMTPVDAIKAGADYLVIGRPVTQAAHPLDVLRKINLSLA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RL21_PROMA
Sequence: MSFDFMTPNKTKNSTVGNYAIVETSGTQFWLEADRYYDIDRINANVDETVTLDKVLLINDQKGFAIGKPYIKGASVQLKVMAHKRGPKIIVYKMRPKKKTRTKNGHRQELTRVMVTSISNGEKPKKATTSAKPNTKKPSTAVKSSKVEKTPE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GLMM_PSEP1
Sequence: MSRKYFGTDGIRGRVGEYPITPDFMLKLGWAAGMAFRKQGHCRVLVGKDTRISGYMFESALEAGLSAAGADVMLLGPMPTPAIAYLTRTFHAEAGIVISASHNPHDDNGIKFFSGQGTKLPDEVELMIEELLDQPMTVIESGKLGKVSRINDAAGRYIEFCKSSVPSSTSFEGLKLVVDCAHGATYKVAPSVFRELGADVTVLHAQPDGLNINEGCGSTHIESLQAAVLVGHADLGIAFDGDGDRVLMVDHTGAIVDGDELLFIIARDLQEHGKLQGGVVGTLMSNLGLELALKDLDIPFVRAKVGDRYVMAELLEREWLVGGENSGHVVCCNHTTTGDAIIAALQVLMALKRRGETLAQARQALRKCPQVLINVRFGASKVDPLEHPAVKEASAKVTDALAGRGRVLLRKSGTEPLVRVMVEGEDESQVRAHAEALAKLVSEVCV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ACT3_SOLTU
Sequence: MAEGEDIQPLVCDNGTGMVKAGFAGDDAPRAVFPRIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVSNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDHLMKILTERGYSFTTTAEREIVRDVKEKLSYIALDFEQELETSKTSSSVEKSYELPDGQVITIGAERFRCPEVLFQPSLIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFPGIADRMSKELTALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWIAKAEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-58.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: T2A1_NOSS1
Sequence: MPYQYHIQSNDDLVTPYQEVRAGFVALALERNRKATPFVEQARALKIRVSQIERPQDLLQMRDIRPTLLAASGVSDKAAGHLQEQDKVDAIEGLIQNFLEPAGENFVEELVYRFLLTRGDTLGGSMRNVGGILAERKFARYIISALTLSNTSYKWLDKNSKTWLNQPDDDTDIELRLRGLSWNLEGRNRTFIYNVNVPIVRKNIDICLFDCRQNEIEKNIISNPNIYIALGELKGGIDPAGADEHWKTANSALARIRTAFDRHSLKPYTFFVGSAIEKSMAEEIWHQLNSGILTNAANLTQPDQVASLCAWFIQL
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CYCGRG-3' and cleaves after C-1.
What are the official names of this protein?
Type II restriction enzyme AvaI, R.AvaI, Endonuclease AvaI, Type-2 restriction enzyme AvaI.
Protein: CML38_ARATH
Sequence: MKNNTQPQSSFKKLCRKLSPKREDSAGEIQQHNSSNGEDKNRELEAVFSYMDANRDGRISPEELQKSFMTLGEQLSDEEAVAAVRLSDTDGDGMLDFEEFSQLIKVDDEEEKKMELKGAFRLYIAEGEDCITPRSLKMMLKKLGESRTTDDCRVMISAFDLNADGVLSFDEFALMMR
What is the function of this protein?
Potential calcium sensor that binds calcium in vitro.
What are the official names of this protein?
Calcium-binding protein CML38, Calmodulin-like protein 38.
Protein: YQGF_CERS5
Sequence: MIHESIEEFLAALPRSGALIGLDLGTKTIGVAVTDGLRRIATPLLTIRRTKFTEDAARLRAITAERGLVGIVLGLPRNMDGSEGPRAQSTRAFARNLSQVLPLPIGYWDERLSTVAAERALIEADTSRKRRAEVIDHVAAGYILQGVLDRLDWLGRERNA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_BORPE
Sequence: MPEETLLAFDFGEKKIGIAIGNTLTRQARPLEIIFSETRAARFGRIGQLLQEWQPQRAVVGLPLTLDGQEQPASARARRFANQLHGHFGLAVELVDERSSSMEAQQLLGTHADDDAVAAAVILQRYLDTLSQP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_CUPTR
Sequence: MTPNSLLSAPSADGVWHHCHLLPDADPARAIRDGALVVEHGRIAWLGAAADLPEAWRGAPRHDANGAWITPGLVDCHTHLVYGGQRADEFAMRLAGAGYEEIARAGGGIVSTVRATRGADEDTLFAQAAARLQPLLAEGVTAIEIKSGYGLNLESERKQLRVARRLGEHFGISVYTTFLGAHALPPEYADRADDYIELVCNTMLPALADEGLVDAVDAFCESIGFSIAQTERVFDAAARHGLRVKLHAEQLSNLGGAALAARHRALSADHLEHLDEAGVAAMAEAGTVAVLLPGAYYFLRDTNLPPIALLRQYGVPMAISTDHNPGTSPVTSLLLMMNMACTLFRLTVPEALAGVTAHAARALGADDRHGRLAVGRVADFALWRIDSPAELAYWFGRNPVATVVRQGRVHAGAGAAA
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_MAGMM
Sequence: MDKILVRGGNTLKGTIPISGAKNACLPELAATLLTEDTVTLRNVPHLRDVTTMLELLGQHGAAITIDEKLGVSIDCKSIQNTMAPYDLVRTMRASVLVMGPLVARCGHAEISLPGGCAIGSRPINLHLRGLEMMGAHVTLEDGYVRIKAGRLKGAHIVFDLVTVTGTENLLMAATLADGITILDNAAAEPEVVDLANLLMAMGAKIDGAGTRTITIEGVKNLHGTSHDILPDRIETGTFMVAAAVTGGDITMTGTYPALLEAHIAKMREAGCQIDEMDRAIRVRAEAGTLRAVDITTLPHPGFPTDLQAQMMVLLTVAKGAAQIKETIFENRFMHVSELQRMGADITVQGNTAIVRGVPQLRGAPVMATDLRASASLVLAGLCAEGETLISRVYHIDRGYERIEEKLKALGADIQRLGR
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_MALP2
Sequence: MRKNRATKREILPDPVYNSRLVTKAINAIMLEGKKGLAQQIVYQSFDLIKKKTNEDGIEVFKKALENIMPSLELRVRRVAGSNFQVPTVVSKERKQTLGLRWLILSARKRNEKSMIEKLAAEIIDASKGTGAAFKKKEDTHKMAEANKAFAHLRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: DNAJ_YERPA
Sequence: MAKRDYYEVLGVSRDAEEREIKKAYKRLAMKFHPDRQSEDKNAEEKFKEAKEAYEILTDAQKRAAYDQYGHAAFEQGGMGGGGFGGGGGGADFSDIFGDVFGDIFGGGRRQQRASRGSDLRYNMDLTLEEAVRGVTKEIRIPTLDECDVCHGSGAKPGSSPVTCPTCHGAGQVQMRQGFFTVQQACPHCHGRGQIIKDPCNKCHGHGRVEKSKTLSVKIPAGVDTGDRIRLSGEGEAGEHGAPSGDLYVQVQVKAHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKIPAETQTGKMFRMRGKGVKSVRGGSQGDLLCRVVVETPVSLSEKQKQLLRELEESFVGAAGEKNSPRAKSFLDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRPS1_MOUSE
Sequence: MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL
What is the function of this protein?
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 1, Phosphoribosyl pyrophosphate synthase I, PRS-I.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
Protein: RL14_THEPX
Sequence: MIQPQTRLKVADNTGAKEIMCIRLEGGSNRKFSNVGDVIVASVKSATPGGVVKKGEVVKAVIVRTKKGIARKDGTYIRFDDNAAVIIRDDKQPRGTRIFGPVARELREKDFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TMX2_BOVIN
Sequence: MAVLAPLIALVYSVPRLSRWLARPYYFLSALLSAAFLLVRKLPPVCESLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHVGNIFMFSKVANAILFFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEYIKYFSDKTIDEELERDKRVTWIVEFFANWSSDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEVMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDKIPEEQPVAAVPAAVPDEESKKDK
What is the function of this protein?
Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity.  Indirectly regulates neuronal proliferation, migration, and organization in the developing brain.
What are the official names of this protein?
Thioredoxin-related transmembrane protein 2, Thioredoxin domain-containing protein 14.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Mitochondrion membrane. Note=Localizes to endoplasmic reticulum mitochondria-associated membrane (MAMs) that connect the endoplasmic reticulum and the mitochondria.
Protein: PHOP_SALTS
Sequence: MMRVLVVEDNALLRHHLKVQLQDSGHQVDAAEDAREADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSSDVSLPVLVLTAREGWQDKVEVLSSGADDYVTKPFHIEEVMARMQALMRRNSGLASQVINIPPFQVDLSRRELSVNEEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPHDVITTVRGQGYLFELR
What is the function of this protein?
Member of the two-component regulatory system PhoP/PhoQ which regulates the expression of genes involved in virulence, adaptation to acidic and low Mg(2+) environments and resistance to host defense antimicrobial peptides.  Essential for intramacrophage survival of S. typhimurium.  In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG).  In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG.  Essential for transcription of spiC inside macrophages by controlling the expression of the two-component regulatory system SsrB/SpiR (SsrA) and Pir at transcriptional and post-transcriptional levels respectively.  Promotes expression of the two-component regulatory system PmrA/PmrB via activation of pmrD gene.  Is required to attenuate bacterial growth within fibroblast cells and to enhance bacterial resistance to bile in intestinal cells.  Negatively regulates prgH, which is required for invasion of epithelial cells.  PhoP uses multiple mechanisms to promote transcription and activates promoters for PAG at low (uM range) Mg(2+) concentrations.  Involved in acid tolerance (Probable).
What are the official names of this protein?
Virulence transcriptional regulatory protein PhoP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NT1AA_XENLA
Sequence: MSTELVEDETQFYGKAQNYWKNVPPTVDGMLGGYGHISNVDLNGSKKFLQRFLRQEGSNKTGNACALDCGAGIGRITKRLLLPLFKTVDMVDVTDEFLNKAKSFLGEEGKRVGNYFCCGLQEFSPEPNRYDVIWIQWVIGHLTDEHLVNFLQRCRLGLRPNGIIVIKDNVTQDASIMDDVDSSICREIDLVRKLIKQAGLSILAVERQENFPDEIYHVFSFAMR
What is the function of this protein?
Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved.  Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif.  Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on target proteins.
What are the official names of this protein?
N-terminal Xaa-Pro-Lys N-methyltransferase 1-A, Alpha N-terminal protein methyltransferase 1A-A, Methyltransferase-like protein 11A-A, X-Pro-Lys N-terminal protein methyltransferase 1A-A, NTM1A-A.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. NTM1 family.
What are the subcellular locations of this protein?
Nucleus. Note=Predominantly nuclear.
Protein: FNDC5_HUMAN
Sequence: MHPGSPSAWPPRARAALRLWLGCVCFALVQADSPSAPVNVTVRHLKANSAVVSWDVLEDEVVIGFAISQQKKDVRMLRFIQEVNTTTRSCALWDLEEDTEYIVHVQAISIQGQSPASEPVLFKTPREAEKMASKNKDEVTMKEMGRNQQLRTGEVLIIVVVLFMWAGVIALFCRQYDIIKDNEPNNNKEKTKSASETSTPEHQGGGLLRSKI
What is the function of this protein?
Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
What are the official names of this protein?
Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Peroxisome membrane; Single-pass type I membrane protein. Note=Imported in peroxisomes through the PEX5 receptor pathway. SUBCELLULAR LOCATION: [Irisin]: Secreted. Note=Detected in the blood of individuals subjected to endurance exercise.
Protein: MURG_AZOVD
Sequence: MGANVLIMAGGTGGHVFPALACAREFQARGYAVHWLGTPRGIENDLVPSAGLPLHRIQIGGLRGKGLATLLKAPFQLIRSLFQARRIMNELRPVCVLGMGGFVTGPGGVAAKLTGAPLVIHEQNAVAGTSNRALAPLADRICEAFPDTFKPTGKRRTTGNPVRSELFLDSSRQIPDGRRLRLLVLGGSLGAEPLNKLLPAALALIPVEQRPELFHQAGRQHHESTADRYREAGVEAEVVPFIEDMARVYAWADLVVCRAGALTVSELAAAGLPALLVPLPHAIDDHQTRNADYLAREGAAFLLPQATTTAADLAARLSEVSMHPEQLEGMAARARRLAKPDATRTVVDICLEVARG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL15_EHRCJ
Sequence: MNTVVKLNNIFSGLPKKKKTKVLGRGIGCGKGKTSGRGHKGQKARSGVSINGFEGGQQSIFTRLPKRGFNSLFKSKYSIVNLSTIQRLIDSKKIENVSAITKQVLFNLGVIPSIKEKIKILGDGKLNTAVAIEYDFISKSAGSQVTLLSSVSEDKV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: VTU4_DROYA
Sequence: MKIVAFTLVAFVALAGASCPYAAPAAAPAPAAPSGYPAPPCPTNYLFSCQPNLAPAPCAQEAPAYGSAGAYTEQVPQYVGNPSREQVQQFHQRIGMAALMEELRGLGQGIQGQQY
What is the function of this protein?
Major early eggshell protein.
What are the official names of this protein?
Vitelline membrane protein Vm32E.
What is the protein family that this protein belongs to?
Belongs to the vitelline membrane family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPD_ECOK1
Sequence: MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFANYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_GEOUR
Sequence: MAKLDVFDIKNKKVGEIELSDSVFNDEVKEYLIHEAVKIQLANRRAGTVGVKNRSAVAGSGKKPFKQKGTGQARQGCRRAPQYPGGGVAFGPQAKTYNLSMNKKARRAAMRSALSLLFKNNKLTVLNNIDLDNVSTKNFVGILNGFTLDKTLVVTDVENRNLELSARNVKNVKVLKSEGLNIFDIMKYQSVIFTENSVRKVEGALQS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RP22_FOWPN
Sequence: MMNQYNVTYLSKILCLKTEILYKPFSIINRSIVNQYNIDVKYDDITSIVKIRHKTENTILVFQIFNESNVKYSPIEYDYGDPIIITSNLQHGHNRIPINMLYIDVVESDMFPTFSRLDSETIKIITSILQSDNKKEQSIKLPKVSENELSVKILYHKDYPLKYVRYYKNNMVTGIEVIDRSVAITS
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 22 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 22 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).