PharMolix/UniProtQA huggingface dataset:
Protein: ATP25_AJECH
Sequence: MSRVLLRGIQCHACRSNVIRSFISVSDVAITPLAGGSRSTAQARPPPLSRNFSSQHAKLFSNQPSDNAELVVDPIPEIHTGEETEGQPEESQEHIPWYLKEEQVEETIPHPLRKQQPLPPLPENPPPILENLLEHISVDIGLDNLSLLDLRRLDPPPALGANLIMIFGTARGVKHLNVSADRLCRWLRTTYKLRPDADGLLGRNELKIKLRRKARRAKLAKSAKSTLTQPDDGITTGWICVDVGTVEGGQFRKPEEELRKVGFVGFGTVVEGTRIVVQMMTEEKRQEIDLEGLWRQKLERNSLENEGLPQPQAAAPQEAGDIHEQLTVPPTNISHQISHATQISANYEQRRGISTGSRRYQDATSDTWGTSQISPNSETTHLEPSAPSSLTSLSHHFKNIPPHEAIYDLGQGTHDRCSTAFLQQFYQEVARAPSELASSRRIELMCIAIELHHPGYRKPDLFQAIQEHVLSNYALTRAQFLQILDAFLSFKPDLTSNPPRLLLPNADMELALQIIDHAGLRGLNLLDSTILVKLFVGVSFRAQVYPVKEKDLPNSPVIGNRIPVPLNTCDAVKRVQSRLTRVKTAAKITFTTEQYMRILRVLFDQGSYSEFWNTWEDMALAGIARDKALYVFLFQLHAESDGWQCFTTQLLNCIPMMERENPPVHLDGELAEVTQKCITIAYPEIIDRVERNEQNPLVRMWHRCRVAIENAAAAGGRGQDSTAPYVCNHSDI
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: NHAA_RICCN
Sequence: MVESGIHDTLCRAIIALFIPVNIKGEFNTSFKKLENLTRPFVNYFILPLFVFMNSGILLEYFAFKGICSNSILALIYGIIFGLFVGKQLGIMLFSYPFVKFKLCNLPSDTSWLKFYSIAILGGIGFTLSLFIGSILRLRAAALQTL
What are the official names of this protein?
Putative Na(+)/H(+) antiporter NhaA homolog.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR11_MORIN
Sequence: MAKPLPRIGSRKNRHMGSRKNVRRIPKGVIHVQASFNNTIVTVTDVRGRVISWSSAGTCGFKGTKRGTPFAAQTAAGNAIRTVVDQGMQRAEVMIKGPGLGRDAALRAIRRSGILLSFIRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACSA_VIBPA
Sequence: MSEAHVYPVKENIKTHTHADNDTYLAMYQQSVTDPEGFWNEHGKIVDWIKPFTKVKSTSFDTGHVDIRWFEDGTLNVSANCIDRHLAEHGDDVAIIWEGDDPADDKTLTFNELHKEVCKFSNALKDQGVRKGDVVCLYMPMVPEAAIAMLACTRIGAVHTVVFGGFSPEALSGRIIDSDAKVVITADEGVRGGRAVPLKKNVDEALTNPEVKTISKVVVLKRTGGNVDWHGHRDVWWHEATAKVSDVCPPEEMKAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAAMTFKYVFDYQPGETFWCTADVGWITGHTYLIYGPLANGAKTILFEGVPNYPNTSRMSEVVDKHQVNILYTAPTAIRALMAKGNEAVAGTSRSSLRIMGSVGEPINPEAWEWYYKTIGNENSPIVDTWWQTETGGILIAPLPGATDLKPGSATRPFFGVQPALVDNMGNILEDTVAEGNLVILDSWPGQMRTVYGDHERFEQTYFSTFKGMYFTSDGARRDEDGYYWITGRVDDVLNVSGHRMGTAEIESALVAHHKIAEAAIVGIPHDIKGQAIYAYITLNDGEFPSAELHKEVKDWVRKEIGPIATPDVLHWTDSLPKTRSGKIMRRILRKIATGDTSNLGDTSTLADPSVVDKLIAEKAELV
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: NXF1_BOVIN
Sequence: MADEGKSYNEHDDRVSFPQRRKKGRGPFRWKSGEGNRRSGRGGSSVRSSRLEDDDRDVAMSDVQDAPRVRYTPYAARPNRRGDNWNERTRIHVTLPLRRDRSAAERGGAGTSQDGTSKNWFKITIPYGRKYDKSWLLNVIQSKCSVPFTPIEFHYENTRAQFFVEDASTASALKAVNYKILDRENRRISIIINSSSPPHSVQNELKPEQVEQLKLIMSKRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPELLSLNLSNNKLYRLDDLSSIVQKAPNLKILNLSGNELKSERELDKIKGLKLEELWLDGNTLCDTFRDQSTYISAVRERFPKLLRLDGHELPPPIAFDVEAPTTLPPCKGSYFGTETLKNLVLHFLQQYYAVYDSGDRQRLLDAYHDGACCSLSIPFTPQNPARSNLAEYFKDSRNVKKLKDPTLRFRLLKHTRLNVVAFLNELPKTQHDINSFVVDISAQTSTLLCFSVNGVFKEVDGKSRDSLRAFTRTFVAVPASNSGLCIVNDELFVRNASADEIQRAFAMPAPTPSSSPVPTLSPEQQEMLQAFSTQSGMNLEWSQKCLQDNNWDYTRSAQAFTHLKAKGEIPEVAFMK
What is the function of this protein?
Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway).  The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex.  ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.  Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export.
What are the official names of this protein?
Nuclear RNA export factor 1.
What is the protein family that this protein belongs to?
Belongs to the NXF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle. Cytoplasm. Nucleus. Note=Localized predominantly in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. Shuttles between the nucleus and the cytoplasm. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. The association with the TREX complex seems to occur in regions surrounding nuclear speckles known as perispeckles. Nucleus; nuclear rim.
Protein: PXPA_PYRFU
Sequence: MKVDLNSDLGESFGRYKLGLDDEVMKYITSANVACGWHAGDPLVMRKTVRLAKKNNVQVGAHPGYPDLMGFGRRYMKLTPEEARNYILYQIGALYAFVKAEGLELQHVKPHGALYNAMVKEEDLARAVIEGILDFDKRLIVVTLAGSRVVEIAREMGARVAQEGFADRAYNPDGTLVPRSRPGAVIEDKEEIAERVISMVKDGGIRAINGEWIELEVDTICVHGDNPKAVEITAYIRRRLEEEGVKVLPMGDFIK
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RL21_VEREI
Sequence: MYAVIKTGGKQYRVAAGENIKVEQIAADVGQEIVIDQVLAVGNGAELKVGTPLVSGASVKATVVAHGKRDKVHIFKMRRRKHYQKRQGHRQQFTELHIGAIAV
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TF2AA_DROME
Sequence: MALCQTSVLKVYHAVIEDVITNVRDAFLDEGVDEQVLQEMKQVWRNKLLASKAVELSPDSGDGSHPPPIVANNPKSHKAANAKAKKAAAATAVTSHQHIGGNSSMSSLVGLKSSAGMAAGSGIRNGLVPIKQEVNSQNPPPLHPTSAASMMQKQQQAASSGQGSIPIVATLDPNRIMPVNITLPSPAGSASSESRVLTIQVPASALQENQLTQILTAHLISSIMSLPTTLASSVLQQHVNAALSSANHQKTLAAAKQLDGALDSSDEDESEESDDNIDNDDDDDLDKDDDEDAEHEDAAEEEPLNSEDDVTDEDSAEMFDTDNVIVCQYDKITRSRNKWKFYLKDGIMNMRGKDYVFQKSNGDAEW
What is the function of this protein?
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.  TFIIA in a complex with TBP mediates transcriptional activity.
What are the official names of this protein?
Transcription initiation factor IIA subunit 1, General transcription factor IIA subunit 1, dTFIIA-L.
What is the protein family that this protein belongs to?
Belongs to the TFIIA subunit 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FGF11_MOUSE
Sequence: MAALASSLIRQKREVREPGGSRPVSAQRRVCPRGTKSLCQKQLLILLSKVRLCGGRPTRQDRGPEPQLKGIVTKLFCRQGFYLQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASALYRQRRSGRAWYLGLDKEGRVMKGNRVKKTKAAAHFVPKLLEVAMYREPSLHSVPETSPSSPPAH
What is the function of this protein?
Probably involved in nervous system development and function.
What are the official names of this protein?
Fibroblast growth factor 11, FGF-11, Fibroblast growth factor homologous factor 3, FHF-3.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMA_NITOC
Sequence: MNTLGHRARKRFGQHFLHDKGVIERLLRAINPQLNDLMVEIGPGQGALTLPLLHCLGHLEAIELDRDLAAYLVERCASEGNLRLHNVDSLTFDFRTLAHENRRLRVVGNLPYNISTPLLFHLLGQIGILEDMHFMLQREVVTRLAAKPGGKDYGRLSVMVQFYCEVEPLFTVKSGAFVPPPKVDSMVVRLIPHRPSLAPNISHGALNRVVSQAFSQRRKTLANALKGLLSSAELIALGIDPRQRPETISLEDYLALTRYWLKAQ
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_GLUDA
Sequence: MPAITLPDGSVRRFDGPVTGTMVAESIGPGLARAALAMEVDGALVDLSREIADDASVRFITRKDDAALEMIRHDTAHVLAEAVQSLWPGTQVTIGPSIENGFYYDFYRNEPFTPEDFPAIEARMREIVAANARFEREVWPRDEAIRFFENRGERFKAELIRDLPESEPISIYRQGEWLDLCRGPHLRGTADVGSAFKLMKVAGAYWRGDHRNPMLTRIYGTAWRDQKELDAHLHRLEEAERRDHRRIGREMDLFHIQEEAVGSIFWHPKGWRLYTALQDYMRRAQTRGGYQEVRTPQLVDRALWEASGHWDKYREHMFIATVEDEDKTLALKPMNCPCHVQIFRHGLRSYRELPLRMAEFGACHRYEPSGALHGIMRVRSFTQDDAHIFCTESQIAAETARFVRMLAEVYADLGFESFRVKFADRPEQRAGSDETWDRAEGALIEACRLAGVEYEYNPGEGAFYGPKLEFVLRDAIGRDWQCGTLQVDYVLPERLDASFVGEDSARHRPVMLHRAILGSFERFLGILIEQHAGRFPLWLAPVQVVVASIVTDAAPYAEQVAETLTQAGLVVETDIRNEKINAKVREHSLARVPVILVVGRKEAEDGTVAIRRLGGAAQEVMSLADAATALAAEALPPDLRR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_STAAW
Sequence: MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLSSIPFNANWLNQQYAEIIQAILFDVVGYEVKPHFITTEELANYSNNETATPKETTKPSTETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLIDDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIVDITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLLGKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEIRNV
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF34_MOUSE
Sequence: MKAGATSMWASCCGLLNEVMGTGAVRGQQAGFPGSTGPFRFTPSSDFPTYPPAATEGPNIVCKACGLSFSVFRKKHVCCDCKKDFCSLCSVSQENLRRCSTCHLLQETAFQRPQLMRLKVKDLRQYLLLRNIPTDTCREKEDLVDLVLCHRGLGSGDDLDSSSLNSSRSQTSSFFTQSLFSNYTPPSATVSSFQGELMDRDGAFRSEVLAQVQSEIASANTDDDDDDDDDDDDDEDDDDEQEEEEQNPGLSKKKARASLSDLSSLEEVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERMQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVFKS
What is the function of this protein?
E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins.  Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis.  May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway.  Negatively regulates p53/TP53 through its direct ubiquitination and targeting to proteasomal degradation.  Indirectly, may also negatively regulate p53/TP53 through ubiquitination and degradation of SFN.  Mediates PPARGC1A proteasomal degradation probably through ubiquitination thereby indirectly regulating the metabolism of brown fat cells (PubMed:22064484).  Possibly involved in innate immunity, through 'Lys-48'-linked polyubiquitination of NOD1 and its subsequent proteasomal degradation.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF34, Phafin-1, RING finger protein 34, RING-type E3 ubiquitin transferase RNF34.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endomembrane system; Peripheral membrane protein. Nucleus. Nucleus speckle. Cytoplasm, cytosol.
Protein: COXX_MYCTO
Sequence: MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GALT6_CAEEL
Sequence: MIASLIRSRRRSRRCVVYSVFLFGFLALWGSFALALVFLSDMYIGEDQISTQKAIKPIARSNYHVVVGHYNGNLPEDKKRNLTSEELNANLYAPHDDWGEGGAGVSHLTPEQQKLADSTFAVNQFNLLVSDGISVRRSLPEIRKPSCRNMTYPDNLPTTSVIIVYHNEAYSTLLRTVWSVIDRSPKELLKEIILVDDFSDREFLRYPTLDTTLKPLPTDIKIIRSKERVGLIRARMMGAQEAQGDVLTFLDSHCECTKGWLEPLLTRIKLNRKAVPCPVIDIINDNTFQYQKGIEMFRGGFNWNLQFRWYGMPTAMAKQHLLDPTGPIESPTMAGGLFSINRNYFEELGEYDPGMDIWGGENLEMSFRIWQCGGRVEILPCSHVGHVFRKSSPHDFPGKSSGKVLNTNLLRVAEVWMDDWKHYFYKIAPQAHRMRSSIDVSERVELRKKLNCKSFKWYLQNVFQDHFLPTPLDRFGRMTSSSNSSVCLAWTLRSSGIKTASTADCLKIFHKTQLWLYTGDRRIRTDEHLCLSVVQLLHTTSDWKIQLKECAGFDTEYWDFKPKIGRFQNRKTGLCLASPDIFDPTKDEFNPPIVQKCRSSNDRQNWTITEMSWLPEHP
What is the function of this protein?
Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis.  Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity).  In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested.  Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
What are the official names of this protein?
Probable N-acetylgalactosaminyltransferase 6, Protein-UDP acetylgalactosaminyltransferase 6, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6, pp-GaNTase 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: FABA_HALHL
Sequence: MVKQHSYNRDELLLSGHGRLFGPGNPQLPSPNMLMFDRITRINEDGGQYGKGEVVAELDVHPELWFFRCHFAGDPVMPGCLGLDALWQMVGFYLGWIGGHGAGRALGCGEVKFTGQILPDNRLVTYNVALKRVINRRLVMGIADGSVAVDGETIYEATDLKVGLFQNTGELNGA
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF2_DICDI
Sequence: MTWQAYVDNNLLGAGFASAALLGAADGSVWAHSAGFNVAEGKAITALFQKDGAAFATGIHVAGKKYMAIKSDTRSAYGKLGAGGVVCVKTLTCIIVAVYDDKLQPGAAANIAEKLADYLIDNNC
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-2, Profilin II.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DAPA_STUS1
Sequence: MIAGSMVALVTPMDAQGGLDWDSLSKLVDFHLQEGTNAIVAVGTTGESATLSVAEHIEVIRRVVDQVNGRIPVIAGTGANSTSEAVELTENAKTAGADACLLVTPYYNKPTQEGLYLHFKHIAEAVAIPQILYNVPGRTVCDMLPDTVERLSKVPNIIGIKEATGDLKRGREVLDRVSTDFLVYSGDDPTAVELMLMGGKGNISVTANVAPRAMSELCAAAMAGDAETARAINERLMPLHRALFLEANPIPVKWALHEMGLMGNGIRLPLTWLSQSYQEPLRQAMRQTGVLA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: NU4C_RANMC
Sequence: MNDFPWLTIIVGLPIFAGTLIFFFPHRGNKIIRWYTICICILELLITAYVFCYHFQLDDPLIQLEQDYKWIHFFDFHWRLGIDGLSVGPILLTGFITTLATLAAWPVTRDSRLFHFLMLAMYSGQIGLFSSRDLLLFFIMWEFELIPVYLLLSMWGGKKRLYSATKFILYTAGGSIFLLMGVLGMGLYGSNEPTLNFETSANQPYPVALEILFYFGFLIGYAVKLPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSIFSPWLIIVGAIQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGICSITDTGLNGAILQMISHGFIGAALFFLAGTSYDRIRLVYLDEMGGIAIPMPKIFTMFSSFSMASLALPGMSGFAAELVVFFGLITSQKYLLMPKILITFVTAIGMILTPIYSLSMLRQMFYGYKQFKFKSLNSSFFDSGPRELFVSICIFLPVIGIGIYPDFVLSLSVDKVEAILSNYFYR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: VAP22_ARATH
Sequence: MNMPLLDIQPRTLQFAVDLKKQTSCVVQLTNTTHHYVAFKVKTTSPKKYCVRPNVGVVAPKSTCEFTVIMQAFKEPPPDMVCKDKFLIQSTAVSAETTDEDITASMFSKAEGKHIEENKLRVTLVPPSDSPELSPINTPKQGAVFEDSILKDRLYSQSETLAPPQYEGEIVKEPRMVGHDELKAADNAKELKTPKMATVDFVEDRYTANDLKATKDSYDSSRMAKETGFDPIRSHKDADDGRAIKATTNLDAPMKKAMDLPRDQGFTNGIAVDSEPKISKERDVVQLQKTDGQNVRGLDELKLVKDIEEMKLKVDALESKLKQADSTISKLMEERSISSQHRQSLQHELAELRTKKIVKEVHNGFPLLYVCVVAFIAYVIGHFLRT
What is the function of this protein?
May play a role in vesicle trafficking.
What are the official names of this protein?
Vesicle-associated protein 2-2, Plant VAP homolog 22, AtPVA22, VAMP-associated protein 2-2, Vesicle-associated protein 27-2.
What is the protein family that this protein belongs to?
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Protein: TELL_STAA3
Sequence: MTENKSFKESHPLDDFISDKELSNTTIQKEKLTIEQQKQVDTISKQINPLDNEGLLAFGSDLQKQMSQFSHQMLDEVQSKDVGPIGDTLSDLMSKLKSVNPNELNTDKPSMLKRIFSRAKSSINEIFSRMQSVSAQVDRITIQLQKHQTHLTRDIELLDTLYDKNKQYFDDLSLHIIAAQQKKLQLENEKLPQLQQQAQQSTNQMDIQQVADMQQFIDRLDKRIYDLQLSRQIALQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTLMRQRNAVAAQRAVTDTTNDLLTANAEMLKQNAIETATENERGIVDLDTLKRTQRNIIETIEETLIIQQHGREERQLAEKELQQLEQDLKSHLVNIKGPNKQS
What are the official names of this protein?
TelA-like protein SAUSA300_1299.
What is the protein family that this protein belongs to?
Belongs to the TelA family.
Protein: SPL13_ORYSJ
Sequence: MDRKDKARKNFSSSSSSSAASMAALAAAAAAGDGGAALPSPMEEDKKPRLVASSLAPVAGGGGGGSSSSAAVAAGASSSSSSSSVAAAARRGAGRAGGGAPSGGGGGPRCQVERCGVDLSEAGRYNRRHKVCQTHSKEPVVLVAGLRQRFCQQCSRFHELTEFDDAKRSCRRRLAGHNERRRKSAADTAHGENCRHADQDAGRSHQGTGNPPFQIR
What is the function of this protein?
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3' (By similarity).  May be involved in panicle development.
What are the official names of this protein?
Squamosa promoter-binding-like protein 13.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHKB_DICDI
Sequence: MEKSEQTNSFESSNNNNNNIDSNINNNLENNNNKNNNNNNNNNNNNNNNNNNIENSIDKNNKEDNSLVGVNSHRKHRTRLKSKKGNKHETKKEIDYKDLLIKLPHNAVSNFNSLENESSDNLTPPPPINSSPLPLPLSLPLPLSLPLPLPLPLPLPLPLPPNKENIEINMEDIIIPENKIKNKNNNNNIDINNNNNNNNEKQTSIIEMEDLDKLKQPKINEGSTGKKGKSHFFSFLQRGDKTNSSILKSSEQPTHKKTKTNINTPPDYPIHYFGHHKRFSSSSDEGSDNSKSQHSSVNTPTLSRHNIDSLPESQQSQKQSQQQSQQPQQQNKTKQIQQTILNNNNDNLNEVTPIKKSSLPTLEVSPIQSNIINNQTTEKHNSGGFTALTSASAMNHQNQRRYREHHQINHQQQQQQHHRHYHHHINSGGSSGSSDKFDYVSATGLSTKNGFNPKSLDVDHFPISDKRNNINIQAPSTPVQSRNYPLFTTQSPKNANSASKSKNKLKNLKRKIASSITGNNPSGISSSAFNHSFSSWNNNNSVYTGGNSGGGSGGGGSGGGGGGGGGGGGIGTPSSFLDDNNNLNNGENFKNSNSYNNNNGSNRSISHDEWLRQFYHKHLERYEKTKAVDYLIIKPWNFISWILRPSRIANYQSKILYRRAYILNFLNLVLFVVYLLSTILSSNEWFIFAPGILLSVIYFFLGKINNKMYLIAFLTISTAVAINITSIIYDLTHTRPTDKLIFSWDLLVMIMVPLLFPSIVYSIVILISVAVTYIGLGIYVQSSHNFYLLDAYDSFGELLRSIIIVFVILMFYTILSSVDLKEIERKESRIQSLFRISNEALVVHKDGLITDANPAFESMFQIKLQDLLYPIQSGIWEFLPALEGMFEPGASKLFDNPDMGVIETTGIDSSGRTFQVEVRTNKATYDGEPVDVISIIDITGRKQLMEADYALRKAEAANEAKVIFLTTVSHELRTPINGVLASADILERTTLDSTQKEFLNCIKLSGNYLLDLINDILDYSKIEAGKMEIIKYDFSILKMLDNSIRIVSKNIYEKGLDLCIFIDPNVPVIVNGDQRRIKQILLNFLSNSIKFTNHGQIIIRVKLESDDSTHSLIKFDVEDSGIGIKTEHLNQLFASFSQIDSGNSRKYQGTGLGLSISKRLCKMMGGDVKVKSEFGVGSTFSFTIPCGIPNTTTRFSLQSLGSAIYMGEDIQGINKPIGKKKYGASGVVGIVIDSNKYTRKSISQYFAILKISCVDFENKKEFENYLSTLATVDQTTNPQVYLVITSIIDINQLTTNGLPRDRIYHWILMESPNEERKLPLEFENRFVKPAQFADIVRCLYKIDSINFFIEQMAGSPYKASKDLQSGGSSNESGDGGRSLSGGGGGVGSNGNGNGGGGLDSNISPSELSSSEHQLISTPLSDVNEFEDINLINQSLSGLGPSAKVLNSTYFNGLSQSSKIYNNNNRNGVGIGNHHHDHYYQHRHHHSLPPEEIDYDESPFLFLNKPIRKVYHSQPSTPVTNGIALMDSSSKSPSIPSSSSASASALSPNSRHSNELGNGKTTQSFVFSPTSRKFSLNDSFNPSISTIVLPQVSYSPSMQGGNFPINMESVYKKIESHNNNFKRSESKPSTPTFLSNQPSPATSNSPQLLQSPTTSTTGSINLSPHRSPNIRLPLEVRSGSLSSLKPLREDEELESISDDHTSHLKGSSHSINQQIPSTIQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQKPQQQQQKPTTTTTTTSTQLPQNIEKTTTTTTTSTTKPTATSSSSSSSKTTKTQQQQHHPTTTTTTKSEKIEKTAAATTSEKIEKILLVEDNFVNVKIFSKLLKDSGYIFDVAHNGVEAVECVKKGAYDLILMDCQMPEMDGFEATTAIRELEKSNLIESPPSKKHSHVVIVALTANSGYKDKQKCLSVGMNDFLQKPIKTSDILIQMIKKHLN
What is the function of this protein?
Acts in the cytokinin signal transduction pathway that regulates spore germination.  Required for the maintenance of spore dormancy.  Does not appear to act as a cytokinin receptor.  Probably undergoes ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, which is followed by transfer of the phosphoryl group to a conserved aspartate residue in the receiver domain.
What are the official names of this protein?
Hybrid signal transduction histidine kinase B.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.