PharMolix/UniProtQA huggingface dataset:
Protein: PBUE_BACAM
Sequence: MNFKVFLLAASTIAVGLVELIVGGILPQIASDLDISIVSAGQLISVFALGYAVSGPLLLAVTAKAERKRLYLIALFVFFLSNLVAYFSPNFAVLMVSRVLASMSTGLIVVLSLTIAPKIVAPEYRARAIGIIFMGFSSAIALGVPVGIIISNAFGWRVLFLGIGVLSLVSMLIISVFFEKIPAEKMIPFREQIKTIGNAKIASAHLVTLFTLAGHYTLYAYFAPFLETTLHLSSVWVSVCYFLFGLSAVCGGPFGGWLYDRLGSFKSIMLVTVSFALILFILPLSTVSLIVFLPAMVIWGLLSWSLAPAQQSYLIKIAPESSDIQQSFNTSALQIGIALGSAIGGGVIGQTGSVTATAWCGGLIVIIAVSLAVFSLTRPALKRKSA
What is the function of this protein?
Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and inosine, as well as purine bases guanine, adenine and hypoxanthine, and purine base analogs 2,6-diaminopurine and 6-mercaptopurine.  Therefore plays a role in maintaining the cellular purine base pools and protecting cells against toxic purine base analogs.  Modulates expression of the purR and G-box regulons (By similarity).
What are the official names of this protein?
Purine efflux pump PbuE.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. PbuE (TC 2.A.1.2.25) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPE_ACIAC
Sequence: MRTLHDLPAPAKLNLFLHITGRRPDGYHLLQSVFMLIDWCDTLHIELRPDGGISREDMGAGLPADDLCTRAARALQAATGTRQGAHIVLEKSIPAQAGMGGGSSDAATTLLALNRLWGLGLGRTALERIGLSLGADIPFFLRGRNAWVEGIGETIMPLENVHALPQSRFVVVKPEAGLDTKSIFSSPSLERNSERATISGFAAAHYQFGKNVLQPVAETLCPEVSEAIRWLEHKGLQARMTGSGSAVFAQMTHAIDLFDLPTGWRAKVCDNLRLHPLAGWAADED
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: OB57E_DROME
Sequence: MLDQLTLCLLLNFLCANVLANTSVFNPCVSQNELSEYEAHQVMENWPVPPIDRAYKCFLTCVLLDLGLIDERGNVQIDKYMKSGVVDWQWVAIELVTCRIEFSDERDLCELSYGIFNCFKDVKLAAEKYVSISNAK
What is the function of this protein?
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
What are the official names of this protein?
General odorant-binding protein 57e.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
Protein: XER_AGARV
Sequence: MNNLQTHISSYLEYCLAQKRLDEKTIKAYRIDLIQFYNEISISDPCKIASYDLEKYIEKMHLKYKPKSVRRKIASIKAFFHYLEYKNIILQNPFNKIQIHFREPVILPKTIPLYIVEKFLFTIYKQRSAAKTNYQKRNALRDAAIVELLFSTGIRISELCNLKISDVNLIDGVILIYGKGSKERILQIGNSSVLNILKEYKNDFYNEIVQCNHFFSSQSGKPLSDQSVRRMINKYASLSSIDLHITPHMFRHTFATSLLEADVDIRYIQEMLGHSSINITQIYTHVAVSKQKDILINKHPRKDFHF
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.
What are the official names of this protein?
Tyrosine recombinase EUBREC_2677.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR5_SEMEN
Sequence: MDYQVSSPTYDIDYYTSEPCQKVNVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RHAM_AGRVS
Sequence: MAETEKYAFKMQLHPGMEAEYKKRHDAIWPELVALLHEAGVSDYSIHLDRETNTLFGLLTRPKGHGMAALPGHPIMQRWWAHMGDIMATNPDGSPVAVELVPMFYMP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_BRUO2
Sequence: MPDFSMRQLLEAGVHFGHQTHRWNPKMAPFIYGERNNIHILDLSQTVPLLNSALKVVSDTVARGGRVLFVGTKRQASDIIADAANRSAQYYVNARWLGGMMTNWKTISNSIQRLRKLDELLAGEAQGFTKKERLNLEREREKLDRTLGGIKDMGSVPDLMFIIDTNKEAIAIQEAKRLGIPVVAVIDSNCDPDQIDYPIPGNDDAARAIALYCDLIARAALDGIARQQGAMGIDVGAQVEAPVEPALQAPAEGA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SYS_BDEBA
Sequence: MIDIKLLEKKAETGTSYYDEYKQGLVNRGASTEVLEQIMELNKKRKELITQAETAKASQNKLSGEIGKIKREGGDASAILAEVDVLKTQVKELEAKAAEADQQVTNLALVIPNKPHSSVPVGSSEKDNKEIKVVGTPTQFSFKAKEHWELGEALNIIDFERAGKTTGTRFAFLKGAAAQMERALIQFMMDKHSMKHGYTEMIPPFMVNSNSLLGTGNFPKFKEDVFHLEGSDLYLIPTAEVPVTNYYNNEILDEKDLPQSFCAYSPCFRSEAGSAGRDTKGLIRQHQFDKVELMVFAHPDKSHEVHEALTSHAEQILMDLELPFRRVLLCTGDMGFGSAKTYDLEVWLPGQNAYREISSCSNFEDFQARRANIRFRSAGGKPQFVHTLNGSALAVGRTLVAILENYQREDGSVGIPKALQPYMGGRTEIRK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_ANASK
Sequence: MAAALSQGGTAITMKALLEAGVHFGHQTKRWNPKMKPFIFGARNGIYIIDLQKTVGLARNALRFVSDSVAKGGSVLFVGTKKQAQDAIREEASRSGQFFVTNRWLGGTLTNFKTVKQGIDRLKTIEKMAADGTYERLPKKEVAQLEREREKLEKNLGGIKELSRLPSALFVIDTKKEHIAVHEANRLGIPVVAVVDTNCDPEGIDYVIPGNDDAIRSIRLFTGKVAEACIEGKGRYSAWVAEHGGHDERREQEDRDAASERGHKDRRDRRDRRGGPRERREPREDRAAASANVEVVRKGEVAPAAAPEAAPAKE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CHP3_XENTR
Sequence: MGLSHSHSVETRQLVEKTGFSAEQIEHLHKRFNSLSGDLLTIRKGHLNGISDLEVNPIRSKIVDAFFDKRNLRKGSSGYVEEINFEEFLTIMSYFRPLSQNMDEENISVCRKDKLRFLFNMYDTDNDSKITLEEYRKVVEELLSGNPNIEKETARSIADGAMLEAASICVGQMEPDQVYEGITFDDFLKIWEGIDIETKMHIRFLNMESIPSCR
What is the function of this protein?
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity.  Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage.  Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation.  Also involved in granulocytic differentiation in a ERK-dependent manner.  Inhibits the phosphatase activity of calcineurin (By similarity).
What are the official names of this protein?
Calcineurin B homologous protein 3, Tescalcin, TSC.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family. CHP subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Membrane; Lipid-anchor. Cell membrane. Cell projection, lamellipodium. Cell projection, ruffle membrane.
Protein: UPPP1_PARXL
Sequence: MDWLLACKALILGVVEGLTEFLPVSSTGHLIVAGSLLNFTDEHAKTFDVVIQLGAILAVCWEYRRRIGSVVSGLPSRPDARRFTLNVIIATIPAIVLGLLFEKTIKAALFSPVPVAFALVAGGVVILWAESRQRTRGETVARVQNVDDLGALDALKVGLAQCFALIPGMSRSGSTIIGGMLFGLDRRVATEFSFFLAIPIIFGATAYELHKDWHLLSVDALGTFALGFVAAFVSAFACVRWLLRYIAAHDFTAFAWYRIGFGLLILLVGYSGALNWTE
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 1, Bacitracin resistance protein 1, Undecaprenyl pyrophosphate phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHOT_LISIN
Sequence: MSAYPKFDVILKALNLSSVGVIITDPEQKNNPIIFVNTGFENITGYTKEEAIGSNCHFLQGDDTDKEEVAKIRHAINEKSTANVLLKNYRKNGTSFMNELTIEPIYDDNDHLYFVGIQKDVTTEHNYQLELEKSLWEIEKLSTPIVPIKENICVLPLIGSLTHDRFQHMSDYVSEYMDNGKEDYLIMDLSGLADFNEDAVMNLVKFHGFMKLTGVELIITGISPKFAMTLMRYQENLSSLTTYSTIKEALQFY
What is the function of this protein?
Exhibits the same spectroscopical features and blue-light induced photochemistry as plants phototropins, with the reversible formation of a blue-shifted photoproduct, assigned to an FMN-cysteine thiol adduct.  Positive regulator in the activation of the general stress transcription factor sigma-B (By similarity).
What are the official names of this protein?
Blue-light photoreceptor, Phototropin homolog.
Protein: CSN7B_HUMAN
Sequence: MAGEQKPSSNLLEQFILLAKGTSGSALTALISQVLEAPGVYVFGELLELANVQELAEGANAAYLQLLNLFAYGTYPDYIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVKGLVSSRH
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.  The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases.  CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
What are the official names of this protein?
COP9 signalosome complex subunit 7b, SGN7b, Signalosome subunit 7b, JAB1-containing signalosome subunit 7b.
What is the protein family that this protein belongs to?
Belongs to the CSN7/EIF3M family. CSN7 subfamily.
Protein: TFE_METMA
Sequence: MVDLNDKVIRGYLRSLVGDDGLKMIEQMPEGNVTDEEIAAKTGVLLNTVRRTLFILYENKFAIVVRERDSNSGWLTYLWHLDFSDIEHQLMREKKRLLRNLKTRLEFEENHVFYVCPQGCVRLLFDEATETEFLCPMCGEDLVYYDNSRFVGVLKKRVEALSSA
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: ACP_ENDTX
Sequence: MADFEARVKEIIVEQLGVDPAEVVTGASFVNDLGADSLDTVELVMAFEEKFGIEIPDEEAEKIQTVGSAIDYVKTHVRK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OGFD1_PONAB
Sequence: MNGKRPAEPGPARVGKKRKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSHEVIVMDMDPFLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHISALRKILFEDFRSWLSDISKIDLESTIDMSCAKYEFTDALLCHDDELEGRRIAFILYLVPPWDRSLGGTLDLYSIDEHFQPKQIVKSLIPSWNKLVFFEVSPVSFHQVSEVLSEEKSRLSISGWFHGPSLTRPPNHFEPPIPRSPHIPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFMKVCEALEHGDVEWSSRGPPNKRFYEKAEESKLPEILKECMKLFHSEALFLLLSNFTGLKLHFLAPSEEDEMNDKKEAEAADITEEGTSHSPPEPENNQTAISNNSQQSNEQTDPEPEENETKKESSVPTCQGELRRWKTGHYTLIHDHSKAEFALDLILYCGCEGWEPEYGGFTSYIAKGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQKKTFPNRTGFWDFSFIYYE
What is the function of this protein?
Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency.  Involved in stress granule formation.
What are the official names of this protein?
Prolyl 3-hydroxylase OGFOD1, 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, uS12 prolyl 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the TPA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AATC_RHIME
Sequence: MEEFHKVRRLPPYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPQSIVDKLCEVVQDPRTHRYSSSKGIPGLRRAQAAYYARRFGVKLNPETQVVATLGSKEGFANMAQAITAPGDVVLCPNPTYPIHAFGFLMAGGVIRSISVEPDESFFPPLERAVRHSIPKPLALILNYPSNPTAQVATLDFYKDVIAFAKKHDIIVLSDLAYSEIYFDDAPPPSVLEVPGATDVTVEFTSMSKTFSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATQALNGDGSDIAEVRAIYKRRRDVMVESFGKAGFEVPPPPATMFAWAKIPEKFRHLGSLEFSKLLVEKADVAVAPGIGFGEQGDDYVRLALVENEHRIRQAARNIKRFLSSADETMHNVISLNAHR
What are the official names of this protein?
Putative aminotransferase AatC.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_FRSFL
Sequence: MEGPASSKPLKDKTNPWGPLIILGILIRAGVSVQLDSPHQVSNVTWRVTNLMTGQTANATSLLGTMTEAFPKLYFDLCDLMGDDWDETGLGCRTPGGRKRARTFDFYVCPGHTVPTGCGGPREGYCGKWGCETTGQAYWKPSSSWDLISLKRGNTPKDQGPCYDSSVSSGVLGATPGGRCNPLVLEFTDAGRKASWDAPKVWGLRLYRSTGTDPVTRFSLTRQVLDIGPRVPIGSNPVTTDQLPLSRPVQTMPPRPLQPPPPGAASIVPETAPPPQQPGAGDRLLNLVDGAYQALNLTNPDKIQECWLCLVSGPPYYEGVVVLGTYFNHTIALKEKCCFYADHTGLVRDSMAKLRKRLTQRQKLFESSRGWFEGSSNRSPWFTTLISAIMGSLIILLLLLILLIWTLYS
What is the function of this protein?
This envelope-like membrane glycoprotein is responsible for ligand-independent activation of the erythropoietin receptor EPOR leading to the abnormally rapid proliferation of erythroid precursor cells.  In the first stage of Friend disease, constitutive activation of EPOR by gp55 causes uncontrolled, polyclonal proliferation of infected erythroblasts, leading to polycythemia (massive increase in the number of mature red cells).  Host susceptibility to SSFV-induced erythroblastosis depends on the expression of the truncated isoform of MST1R receptor tyrosine kinase (MST1R isoform sf-Stk).  Interaction with SSFV gp 55 results in constitutive tyrosine phosphorylation and activation of MST1R isoform sf-Stk (By similarity).
What are the official names of this protein?
Glycoprotein 55, gp55.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Virion membrane; Single-pass type I membrane protein. Note=The envelope-like membrane glycoprotein gp55 is defective in its transport to the cell surface and remains associated predominantly with the rough endoplasmic reticulum (RER) membrane. It is almost not incorporated into virions. Host cell surface expression appears to be a prerequisite for its leukemogenicity (By similarity).
Protein: ALMTB_ARATH
Sequence: MSNKVHVGNIEMEEGLSKTKWMVLEPSEKIKKIPKRLWSVGKEDPRRVIHAFKVGHSLTLVSLLYFMENLFKGIGSNAIWAVMTVVAVLLEFFAVEGLTISEKVILSMAARGRESAAEPHERNEAGNVCHSIKFLPKSIARAKQHHVLNQPY
What is the function of this protein?
Malate transporter.
What are the official names of this protein?
Putative aluminum-activated malate transporter 11, AtALMT11.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter (TC 2.A.85) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RECR_PSEA6
Sequence: MKLSPLILELINAFKVLPGVGPKSAQRMAFHLLERNRSGALQLSQVLHNAMEHVGHCKQCRTFTESELCEICAHPRRSEAGTLCVVESPQDVVAIEQTAEFKGLYFVLMGHLSPIDGIGPSEIGLDELANLLDSKDLTEVILATNPTVEGEATAHYIGQMCSARDIQATRLAHGMPVGGELEYVDGNTLTHAFVGRRSLS
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PYRH_CLOB1
Sequence: MNEPKYKRVMLKLSGEALSGEKGFGFDFDFTKEISEQIKKLVDMGIEVGAVVGGGNIWRGRSGSEMDRTTADYMGMLATCINALALQDSLEQLGVNTRVQTAIEMKEIAEPFIRRRAMRHLEKERVVIFASGTGNPYFSTDTAAALRAAEIEADVILLAKKVDGVYDKDPHKYDDAKKYNKLSYIEVLEQGLQVMDSTATSLCMDNDIPILVFGLDEPCNIIKAVTGEEIGTLVSNSK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFD2_MOUSE
Sequence: MADSSGRVGKSGGSGAGKGAVSAEQVIAGFNRLRQEQRGLASKAAELEMELNEHSLVIDTLKEVDETRKCYRMVGGVLVERTVKEVLPALEGNKEQIQKIIETLSQQLQAKGKELNEFREKHNIRLMGEDEKPAAKENSEGAGAKASSAGVLVS
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
What are the official names of this protein?
Prefoldin subunit 2.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion.
Protein: MTNA_DROPS
Sequence: MSLQSIKYTRGSLEILDQLLLPVQSKYLPVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVEIHPEEFDSKKSLRQELEGKLNYLVSARPTAVNMKMAADELLSLANDLTKDDNVDVAAMKQRFLNATEAMLKKDIADNRAIGAHGAKAILQLVAAAAGAPMAGPVRVLTHCNTGSLATAGYGTALGVVRQLSELGKLEHVYCTETRPYNQGARLTAYELVHEKFPATLVLDSMVAALLRAKNVAAVVVGADRVAANGDTANKIGTYQIAVVAKHHGVPFFVAAPLTSIDLHIPSGDHIIIEERPDREMTHVGEHRIAAPGINCWNPAFDVTPASLITGIITERGVFQPAQLKETITKLLET
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SWS_DROPE
Sequence: MDVLELLRVSGSNMYYSTFLADAWCYYISNQITMTMYLYCALGVLSMLFIGWFVYFKRLARLRLRHEIARSLSAVTMASGGDLRGPRFRKRDKMLFYGRRMLRKMKNVSGQMYSSGKGYKRRAVIRFARRILQLRRENMPLEVRTVEPPAEYLEETMEGSDRVPPDALYMLQSIRIFGHFEKPIFLRLCKHTQLLELMGGDYLFKITDPDDSVYIVQSGMINVYISNADGSTLSLKTVRKGESVTSLLSFIDVLSGNPSYYKTVTAKAIEKSVVIRLPMAAFQEVFKDSPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRFKGSSQGAGPSVYCSQTTRQATGSASATATAAAASGTAGSTHTAVPRPASSLSRYSQDEQHTLSDPNPGIPNLELSGDSVNTLFGEVNGGARLNSYPPLYHQRESDGNLSTRRGSITQQEQPEVGPVPSIDMRLVKSSAVDSLRKELGLPEQDAHIIDPFVEVREMEPNVTLITEGNADDVCVWFVMTGTLAVYQGNADATRIKQDKTDLLIHYVHPGEIVGGLAMLTGEASAYTIRSRNHSRVAFIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRALYRQDESSDSTYIVLSGRMRSVITHPGGKKEIVGEYGKGDLVGIVEMITETSRTTTVMAVRDSELAKLPEGLFNAIKLRYPIVVTKLISFLSHRFLGSMQTRTTTGAPGAPVEANPVTHKYSTVALVPITDDVPLTPFTYELYHSLCAIGPVLRLTSDLARKQLGMNIFDASNEYRLTSWLAQQEDRNIITLYQCDNALSPWTQRCMRQADVVLIVGLGDHSHLVGKFEREIDRLALRTQKELVLLYPETASSKPANTLSWLNARPWVTKHHHVLCVKRIFTRKSQYRINDLYSRVLLSEPNMHSDFSRLARWLTGNSIGLVLGGGGARGAAHIGMLKAIQEAGIPIDMVGGVSIGALMGALWCSERNITTVTQKAREWSKKMTKWFLQLLDLTYPITSMFSGREFNKTIHETFGDVNIEDLWIPYFTLTTDITASCHRIHTNGSLWRYVRSSMSLSGYMPPLCDPKDGHLLLDGGYVNNLPGHLWRYCRASMSIAGVFPPFCDYRDGHLLLDGCYTNNVPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLYKKWNPFTAPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPLINKYQTLSCAGCPETYGLNPSDLFSEDEDCDGYISEPTTLNTDVRRYQVPRGGNSLSLSETEMDMDSDVEMDLKMERKMDKATQSTPPLQSKAQILRRKHSKEEARHEWEIKREQKQELAREQELERERELSQKGTTAGATGYTPNAVIATQTSLIFMDEEDEMDKKKTKDNDRDEVRGSAEDTGKEKEEDKENRSNTNNETKNYL
What is the function of this protein?
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho).  This deacylation occurs at both sn-2 and sn-1 positions of PtdCho.  Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.  Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain.  Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain (By similarity).
What are the official names of this protein?
Neuropathy target esterase sws, Swiss cheese.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Sws tethers Pka-C3 to the membrane.
Protein: MOAA_SULTO
Sequence: MIDRFGRSIEDLRVTLTHVCNFSCFFCHMEGEDNSQSLLSPEEISLVAKVGIEYGIRSVKLTGGEPTLRRDLLQIIRELKDVGIKEVSMTTNGVLLSTLAWKLKEVGLDRVNVSLHSLDKQLFKEITGVDALDKVIEGIKEAIKAGLRPLKLNFVLTKKNISQLDNIINFAIETGVDELHLIELHPVGLGKNTFEYHEKLESIEKILKERADKIEIRSKHYRPRYYLNNLVIEVVKPYANPIFCAGCNRIRLTADGKLKTCLYRQDKEIDIMDILRGDFSLEEKIELIREAYEIAIAIREPNFKYKVESYAPS
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: PYRI_ECO5E
Sequence: MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: RS5_ARTS2
Sequence: MTENNEKDIQVTEAVAAPATETAAPATTDDRRGGARRGERGDRGQGRGDRGGRGGRDGGREAEKSQFVERVVTINRVSKVVKGGRRFSFTALVVVGDGNGMVGVGYGKAKEVPAAIAKGVEEAKKSFFRVPRIGSTIPHRVQGEAAAGVVMLRPASAGTGVIAGGPVRAVLECVGIHDILSKSLGSSNAINIVHATVDALKRLEEPAAVAARRGLPLDEIAPAAMVKALMNQKAGV
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.