PharMolix/UniProtQA huggingface dataset:
Protein: SMK_RAT
Sequence: MKRWQVCQDLRSSPFQEDALTDHYRILASLGQGGFGEVKLASHLLTQTKVAIKVLPKSNKNLLLKSEIEIMKSLDHPHIIKLLHIIDTNENIFIVLEHAVGGELLTRIEDFGYLPEEECNRLFRQMVLALQYCHQRGIIHRDIKPENILLDHKGNVKLSDFGLSTKIVMGQKLTTLCGTLPYCAPELFNLNGYDGQAIDVWSLGVVLYYMATGCLPFQGFTYQAIKQKILSGRYSVNFRLSPDLWDVIAKLLTVNPRERPRVHEILRFNWLKNENEVSPSSLGGNTDSHPDPTILVMMGDMGYEQGQIRESLRERKFDQVMATYLMLREKACSEDKSIKTPHPTQCAQTLKSTGSTTEKQTTLRRGSSLPTLTTFYLPSKLESLNKEKRTTMRHTMPPNLNCFNKSESLNKGRRTIVSHTISPTLNCFNKSESLNKGKRTIVRHTMPPKKTSPVRRICPRLHKSFGMGSASEDSSKRNSSDPSLTIFSSQSFMSAFKYGSTYSKRKAFLQCILHYHASQEEDQYKTTIIPSGKLNTTVPPNSLQEDQPTGHLHNVLTAGAVDNRNLQEKSPPFSTTATKGEGPAIKERESIPSSPRAPREQFRGRSQTPPRAPFRRRVWKTLKSGFLKGLGSLCCCLPIQKKVHPASNRVPPMK
What is the function of this protein?
May play a role in sperm motility, especially in the regulation of flagellar function.
What are the official names of this protein?
Sperm motility kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Smok subfamily.
Protein: ZIPA_PASMU
Sequence: MDLNTILIILGIIALIILVVHGLWANRREKSQYFKSANTFTRDSRLREPPAHIQSASEEKKDANTSTPTAEVSPAQRTFAFEAEKQFAHEQQAVEQAIENIKITLPKEEQPYQAKIEPDTPPTSPALTTIAEVENYANQEEGIDTHSEQLRQQLADLAQQSPSVTLAALQEEQALMESQAQQQASEDVRQDTDATFIMMYVVAPENYQFQGARLAKILDELGFLFGEHNIYHRHSDLSVNSPVLFSVANIEQPGTFDYNMHDFSTVGIALFMQLPSEGNDLMNLRMMIRAAKSIAEDLGGFVLTDQQAIFDDQAEKAYLDKVR
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: IXTPA_FLAJ1
Sequence: MKLVFASNNKNKIAEIQSMLPESITILSLEDINCFEDIPETADTIEGNAILKADYVTQKYGYDCFADDTGLEVDAINGEPGVYSARYAGEQKNADDNMNKLLKALENNKNRSAQFKTVITLNLEGKQYIFTGIAKGEITETKTGTNGFGYDPIFKPENFDKTFAELPLEIKNTIGHRGKAVQQLIDLLTATK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: MRAY_CAMC5
Sequence: MFYYIYELLNFNIFQYITVRAGFSFFIAFCLTVYLMPKFIAWAKAKNAAQPIYELAPQTHQKKAKTPTMGGLVFIGAAVFATLLCARLDNVFVVASLLCLVGFSALGFKDDLNKILGGKNHDGLSPRAKLAVQVLIGLVVSSLLYFHGELGSKFYLPFYKFALLDLGVFAIVFWTIVIVAASNAVNLTDGLDGLASVPAIFSLLTLGVFAYICGHAVFSTYLLLPKIVGVGETVIIAAALIGSLMGFLWFNCHPAEVFMGDSGSLSVGAYIGLMGVMTKNEILLIIIGFVFVMETLSVILQVGSFKIFKKRIFLMAPIHHHFEIKGWVENKIIVRFWLIAILANLIALTALKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14_XANC5
Sequence: MIQMQSYLDVADNSGAKEVMCIKVLGGSKRRYAHIGDIIKVTVKDAIPRGKVKKGEVYDAVVVRTRKGVRRPDGSLIRFDGNAAVLLNNKQEPIGTRIFGPVTRELRSEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RECO_SALG2
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSNLKGALQPFTPLLLRYSGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLNCIQALAGTTGSPEPALRRFELALLGHLGYGVNFTHCAGSGERVDDTMTYRYREEKGFFASVVIDNNTFTGRHLKALEEREFPDVDTLRASKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKMKKD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SCX11_CENEX
Sequence: KEGYPVNIYTGCKYSCWLLGENEYCIAECKEIGAGYGYCHGFGCWCEQFPENKPSYPYPEKSCGRK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin Cex11.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RASP_HALH5
Sequence: MQTLIAFLVMFGVLVSVHEWGHLYFAKRAGILCREFAIGFGPKLFSWKRNETVYTIRLIPLGGYVRMAGEDPELITIKPGYEVGLVFNEKNVVSRIIVNNKSKHPEAQVVQVERIDLERELFIEAYDDDGERKRWDVDPKAEMVQDEEATQIAPYDRQFGSKSVAQRALAIFAGPLMNFVLAFVLLAAYGFMQGIPVEDPVVGNIAENSAAETAGLQKGDYVLSIDGQTLETWVDMTMIIQQHPNEEITFEVERAGQILQIPVTPNQVEGMDGEPIGLVGIERPAPEPATLVSGLQFGATQTYTYMTMIFDVLRLLVTGQFSLDYVAGPVGIVNYTGQAAEMGIFVLLQWTAALSVNLGIVNLLPLPALDGGRLVFLGLEAVRGKPLDPSKESLVHFVGFALLMLLVLVVTWNDINRLFL
What is the function of this protein?
Is responsible for Site-2 cleavage of the RsiW anti-sigma factor.  This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).
What are the official names of this protein?
Zinc metalloprotease RasP, Regulating alternative sigma factor protease, Regulating anti-sigma-W factor activity protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
Protein: ATPB_STAAN
Sequence: MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIAMDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAPAFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSIQAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEHYEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQKGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS3_NITMU
Sequence: MGQKIHPTGFRLSVLKNWSSKWYANGKSFPGMLNEDIKVREYLKKKLAHASVGRVVIERPSKNARITIYSSRPGVVIGKKGEDIEVLRGALQKLMGVPVHVNIEEIRKPEIDAQLIADNIAQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARTEWYREGRVPLHTLRADLDYGVSEAKTTYGVIGIKVWVFKGEVIGRGEQAGAGTAAPQVLPPAGEPETRRPPRRPAGRADARSDGKAGEKKGPRKSDNSSEESATKPAKKPVKPGVNDAAAS
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: LEUD_LEIXX
Sequence: MEKFETVNGVAVPFRRSNVDTDQIIPAVFLKRVTKTGFDDALFHAWRQDPGFILNQEAYQGATVLIAGPDFGTGSSREHAVWALRDYGFRVVLSPRFADIFRGNSGKQGLLTGVISEEDAERLWGAIEAQPGITATVDLVAKTATVGEVQVSFDIDHYTRWRLLEGLDDIALTLRDEVRISEYEAARARWRPKTLPVKL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: CRR16_ARATH
Sequence: MYYSSPTCFVLITIFAVVVTQLIFMRTVSSLNMTNAYLNHKCLANQGKYKPGSWYEKKLQSIIVSIGSGDGFTLGYDMMALGKDSDYVAVTNQCRGDSNGSMCRSCFATAIARVTRCPRYKGAIIWYDQCTLQISPFDTQGKFDKDNDFCMSNKKKMNVDSFGEKWMTFLDNLVGIALKDHLYAAGDTRFGTKKLYGMVQCRLDIYNNSCRECVGHIAVKFQDCWHGKQGARVLGSGCNFRYELYPFVGSNKRGRNLN
What are the official names of this protein?
Putative cysteine-rich repeat secretory protein 16.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: CTTB2_CHLAE
Sequence: MATDGASCEPDLSRAPEDAAGAAAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGDKEKKPVCTNPLSILEAVMAHCKKMQERMSAQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKQVVLMLVKECKQLSGKVIEEAQKLEDVMAKLEEEKKKTNELEEELSAEKRRSTEMEAQMEKQLSEFDTEREQLRAKLNREEAHTTDLKEEIDKMKKMIEQLKRGSDSKPSLSLPRKTKDRRLVSISVGTEGTVTRSVACQTDLVTESADHVKKLPLTMPVKPSTGSPLVSANAKGSVCTSATMARPGIDRQASHSDLIGSSVPAFPPPSANRIEENGPSTDSTPDPTSSTPPLPSNAAPPTTQTPGIAPQNSQAPPMHSLHSPCANASLHPGLNPRIQAARFRFQGNANDPDQNGNTTQSPPSRDMSPTSRDNLVAKQLARNTVTQALSRFTSPQAGAPSRPGAPPTGDVGTHPPVGRTSLKTHGVARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIIDSSRASNTGAKVDNKTVASPPSSLPQGNRVTNEDNLPKSSSPQLPPKPSIDLTVAPAGCTVSALATSQVGAWPAATPGLNQPACSDSSLVIPTTIAFCSSINPVSASSCRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQINAADKNGFTPLCAAAAQGHFECVELLIAYDANINHAADGGQTPLYLACKNENKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPACGNSFNEEESESGVFDLDGGEESPEGIFKPVVPADLINHANREGWTAAHIAASKGFKNCLEILCRHGGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIEPSNCGSDDLECENTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDVTCNNTTDSNIGLSAASIRSITLGNVPWSVGQSFTQSPWDFMRKNKAEHITVLLSGPQEGCLSSVTYASMIPLQMMQNYLRLVEQYHNVIFHGPEGSLQDYIVHQLALCLKHRQMAAGFSCEIVRAEIDAGFSKEQLLDLFISSACLIPVKQSPSKKKIIIILENLEKSSLSELLRDFLAPLENRSTESPCTFQKGNGMSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFKGQAPSPCDPVCKIVDWALSVWRQLNSCLARLGTPEALLGPKYFLSCPVVPGHAQVTVKWMSKLWNGVIAPRVQEAILSRASVKRQPGFGQTTAKRHPSQGQQAVVKAALSILLNKAVLHGCPLPRAELDQHTADFKGGSFPLSIVSSYNSCNKKKGESGAWRKVNTSPRRKSGRFSLPTWNKPDLSTEGIKNKTISQLNYNRNVSLSKQKSLENDLSLTLNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRMFDSSGNNPILSATINNLRMPVSQKEVSPLSSHQTTECSNSKSKTELGVSRVKSFLPVPRSKVTLCSQNTKRSSSSSNTRQIEINNNSKENWNLHKNEHLDKPNK
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: TILS_ZYGCR
Sequence: MLTNPIFYLTNSNTSKASTHSNTNSKSLFNTKREDLQILYKLNQLLIEKSILHPYQRILIAVSGGQDSICLLNILNKLRSTWHWKLGIVHCDHKWYLDSALQAIHVSRLAANMQIDLYQALTTQSVNNEQLARNWRYELIRHVAICHNFSVIVTGHTASDRVETLIYNLIRGSGISGLQSISWKRKLNSMLTIRMRSVEEQIILYSKHVKCYQNRENLLEDKKNVDIYLIRPLLNVSRMELKHLVQNWKLSIWSDCSNQNISICRNRIRHQLLPYLRQYFHPKIDYVLNSCTEVMYTETLYLDSIARYVLSKALSFISMPLNDQTCVKLDFELLRAVPLAIQRRILKYFLDVITHTSVSFKHVEQVRIACLITTNSSNQFAKDSMNFTDQLLINRSIYLPGKKILQVINARFLIICNNIT
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, chloroplastic, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FAF2_PANRE
Sequence: KHEYLRF
What is the function of this protein?
Has effects on muscle tension.
What are the official names of this protein?
FMRFamide-like neuropeptide AF2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DUT_PSESM
Sequence: MHALQAKILDPRIGNEFPLPAYATVGSAGLDLRAMLKEDTLLEPGQTLLIPTGLSIYIGDPGLAALILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSCWNRGQTAFTIAVGERIAQLVLVPVVQARFELVEEFDESQRGTGGFGHSGSH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: SUB7_ARTOC
Sequence: MGFITKAIPLALAAMSVVNGAEILETRAGVQTLADKYIVIMNDGVTEKAFDSHRSWVNRTHRRRLVRRGAKAMGGMKHTYKFPTGMKGYSGHFDEDMINQIAKHSDVKYIERDARVQINAITEQDNVPSWGLARVGSREAGGSTYYYDSTAGEGSTAYIIDTGTDIEHEEFEGRATWGSNFVDDMDMDCNGHGTHVSGTVGGATFGVAKKSNIVAVKVLDCNGSGSNSGVIMGMEWATNDAKKKGADKAVANMSLGGAFSQASNDAAAAIANGGVFLAVAAGNDNVDAANSSPASEPSICTVAASTEQDGKADFSNFGQVVDVYAPGDSITSAKPGGGSQVLSGTSMATPHVAGLAAYFIGLGMPGGPGLCDTIKQKAIDAIANPGAGTTGKLINNGSGK
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 7.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SLX4_PARBD
Sequence: MNPATMTRQLSSDGRMFASSIITVIPDSSPTAAEAIELSSPLSLPSPTSLLDFLSTSTSRGPARSDTDGDKTQGKEVLDTKPILENSFRRENRVVSGTGGKAATGKKLKRRTESPGNVCQSEIHIVPGERIILRQTRPDKKAAKAKRTKKEDGLINRKLYGRVSKANQTVSLQPETKKSAPKGCNDTTQPADNGHINDLDDGLQLEQAIQRRLDWTPTKDTTIPVIDLVGDSPSSCEKSLSGMRSTRTMLSNYEFSGIVGTLGGSRSEGTPDAPTTKRPVELLKVNNLKEISGLSDSRQSSITEDSESATSKPRRVKAKNPPKSKLTTITSYATAKYTVVEKSVDLDPVETLLSDEPGKEKNVAKRTSGARCAKPGRKKSATTEKKNEPPIFKVVPPLEAFKAFDGQELLFGTSSQLANGHSEDRHEQNEGTSHISNSSAFIPLSRSESSSKAPSQTSLGSGFLKLSSSKNLWSAGARDLTGAVLEIDEIDLSEHWMKPSIFESQPKAPLGCKADTQIPPQLGEIDFDNSCQKPLAAIDPPELVTQSETPSEKGDLHKYIVKPTHINSCSQSGSSISVGSPEKPVQDKPIFSGFTTSELAKKVAAYGFKPIKSRDKMIALLEKCWENRNKTSNSVPKLTPGDGLSQVDESTQGQSLGQHLKPNSIPQTATTQVPKVKPDKRDTKSQGVPVPSRRSTSTSKVSRKRTESPSAILVDDDQRSDSTGDSVPPSRPRRPSKSCTPRDRQKSPESFNLPTIPLTIRSGKIPSTGTASETLPSLSTQITAAIKAQPRLRAFNGVKQPTWYEKILMYDPIQLEDLAVWLNTDGFERIGEDREVCPGLVREWCESKGVCCIWRKQRGVRAHCPLVRA
What is the function of this protein?
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BECN1_HUMAN
Sequence: MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
What is the function of this protein?
Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors.
What are the official names of this protein?
Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197.
What is the protein family that this protein belongs to?
Belongs to the beclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein. Endosome. Cytoplasmic vesicle, autophagosome. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). SUBCELLULAR LOCATION: [Beclin-1-C 35 kDa]: Mitochondrion. Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Beclin-1-C 37 kDa]: Mitochondrion.
Protein: CLC4M_HUMAN
Sequence: MSDSKEPRVQQLGLLEEDPTTSGIRLFPRDFQFQQIHGHKSSTGCLGHGALVLQLLSFMLLAGVLVAILVQVSKVPSSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTELKAAVGELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDNRCDVDNYWICKKPAACFRDE
What is the function of this protein?
(Microbial infection) Recognition of M. bovis by dendritic cells may occur partially via this molecule.
What are the official names of this protein?
C-type lectin domain family 4 member M, CD209 antigen-like protein 1, DC-SIGN-related protein, DC-SIGNR, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, DC-SIGN2, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Single- pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Single- pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform 5]: Secreted. SUBCELLULAR LOCATION: [Isoform 6]: Secreted. SUBCELLULAR LOCATION: [Isoform 7]: Secreted. SUBCELLULAR LOCATION: [Isoform 10]: Secreted.
Protein: PROB_SHIF8
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_BACCQ
Sequence: MSKVIETKQQVVTEIADKLRASKSTIVVDYRGLTVSEATELRKQLREAGVEFKVYKNSLTRRAAESAEMAELNEFLTGPNAIAFSNEDVVAPAKVLNDFAKDHEALEIKAGVIEGKLVTLDEVKAIATLPSREGLLSMLLSVLQAPIRNLALATKAVADQKEEQGA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: NIFN_RIPO1
Sequence: MTIVLNPKKPLSVNPLKMSQPLGASLAFLGLKGMMPLFHGAQGCTAFAKVVLVRHFRESIPLSTTAMTEVSTILGGQDHVEQAILTIVDKNKPEIIGLLTTGLTETRGDDMEGILKDIRQKHPQLKNLPIVFVSTPDYKGSLQDGYAATVEQIVATDYNAFIAENARSAVIYPQPQVTVLAGSSLSPGDIQEIKSIIEAFGLMPLVIPDLSRSLDGHLEDGYQSITGGGTTLPQLRSLPHSCYTLAIGESMRGAAEILKDRFGTNYEVFPRLAGLEAVDTFLWRLSQIVTSRCDHHFPIVPNIPALFERQRRQLQDAILDTHFYFGGKKVALALEPDLLHQTAWLLTEMGAKIQAAVTTTKSPLLEDLPVDTVTIGDLEDLEDLSAGVDLIITNSHGTAMAQRLNAPLYRMGYPVFDQLGNGQRCLVGYRGTIQFLFDVGNILLAEEANHNHQLSVGVHVT
What is the function of this protein?
This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).
What are the official names of this protein?
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifN.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: CARA_MARMM
Sequence: MTSTPTPTPTGALALADGSVFLGHGTGATGIALGEVCFNTAMTGHQEILADPSYAGQVVCFTFPHVGNVGANGEDEEAASPQARKAAVGMIARAKITPPASWRADTTFEEWLCTRGIVALTGIDTRALTRKIREGGMQMCAIAHDAAGNIDIEALKAAAAGAPTMEGRELAADVARTEGGDWTEGNWTLGEGYAVGPEDGPRVVVLDYGVKANILRLLTGAGARVAVLPGKASIDDIKALNPDGVVVSNGPGDPAETGKYALPTIKAVLDANIPTLGICLGHQMLALAIGAKTAKMPQGHHGANHPVKNHETGQVEIVSMNHGFAVDGTTLPANAAETHVSLFDGSNSGFKLTDKPVWAVQHHPEASPGPQDSFGVFDRFVGELKGRVEA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: COX2_ZOOAN
Sequence: MTTWSCMNLQDSASPIMEQLIFFHDHTLMIVTMILVSVLYFMTSMTINKNENRYMLEGQTIELIWTIAPAVILVFITTPSLRLLYLMDEIHNPTMTIKTIGHQWYWSYEYSDFIKVEFDSYMTPYEEDNKKMFRLLETDNHVTLPMNSFIRIIVTAADVLHSWTIPSLGIKADATPGRLNQSSFMINRPGLLYGQCSEICGANHSFMPIVIESVSTKKFIEWIKNLSE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.