PharMolix/UniProtQA huggingface dataset:
Protein: RHAD_SALPB
Sequence: MQNITDSWFVQGMIKATSDAWLKGWDERNGGNLTLRLDETDIAPFAANFHEKPRYIALSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGVVKIDSDGAGYHILWGLTHDAVPTSELPAHFLSHCERIKATHGKDRVIMHCHATNLIALTYVLENNTALITRKLWEGSTECLVVFPGGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAEVLVKIYSMGGMKQTITREELVALGKRFGVTPLASAVALY
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTMB_EPIFI
Sequence: MDGFSNMEQAPLAYQEVQWLAETFVTFMGLGWLINYVLMIWHSRRGEPSSMALIPLCNNIAWELVYTIIYPSPNKVELAAFIAGVTLNFLIMTSAARSARSEWSHSPTMAKHAGLIIVAGILMCFTGHVALAMEIGPALAYSWGAVICQLALSIGGVCQLLQQHSTGGTSWKLWSSRFLGSCCAVGFAFLRWRYWPEAYGWLASPLILWSLATFLVADLTYGVCLLL
What is the function of this protein?
Terpene cyclase; part of the gene cluster that mediates the biosynthesis of lolitrems, indole-diterpene mycotoxins that are potent tremorgens in mammals, and are synthesized by clavicipitaceous fungal endophytes in association with their grass hosts (PubMed:16765617).  The geranylgeranyl diphosphate (GGPP) synthase ltmG is proposed to catalyze the first step in lolitrem biosynthesis (PubMed:16765617, PubMed:15991026).  LtmG catalyzes a series of iterative condensations of isopentenyl diphosphate (IPP) with dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and farnesyl diphosphate (FPP), to form GGPP (PubMed:16765617, PubMed:15991026).  GGPP then condenses with indole-3-glycerol phosphate to form 3-geranylgeranylindole, an acyclic intermediate, to be incorporated into paxilline (PubMed:16765617).  Either ltmG or ltmC could be responsible for this step, as both are putative prenyl transferases (PubMed:16765617).  The FAD-dependent monooxygenase ltmM then catalyzes the epoxidation of the two terminal alkenes of the geranylgeranyl moiety, which is subsequently cyclized by ltmB, to paspaline (PubMed:16765617, PubMed:15991026).  The cytochrome P450 monooxygenases ltmQ and ltmP can sequentially oxidize paspaline to terpendole E and terpendole F (PubMed:22750140).  Alternatively, ltmP converts paspaline to an intermediate which is oxidized by ltmQ to terpendole F (PubMed:22750140).  LtmF, ltmK, ltmE and ltmJ appear to be unique to the epichloe endophytes (PubMed:16765617, PubMed:15991026).  The prenyltransferase ltmF is involved in the 27-hydroxyl-O-prenylation (PubMed:22750140).  The cytochrome P450 monooxygenase ltmK is required for the oxidative acetal ring formation (PubMed:22750140).  The multi-functional prenyltransferase ltmE is required for C20- and C21-prenylations of the indole ring of paspalanes and acts together with the cytochrome P450 monooxygenase ltmJ to yield lolitremanes by multiple oxidations and ring closures (PubMed:22750140).  The stereoisomer pairs of lolitriol and lolitrem N or lolitrem B and lolitrem F may be attributed to variations in the way in which ring closure can occur under the action of ltmJ (PubMed:22750140).  While the major product of this pathway is lolitrem B, the prenyl transferases and cytochrome P450 monooxygenases identified in this pathway have a remarkable versatility in their regio- and stereo-specificities to generate a diverse range of metabolites that are products of a metabolic grid rather than a linear pathway (PubMed:22750140).
What are the official names of this protein?
Terpene cyclase ltmB, Lolitrem B biosynthesis cluster 2 protein B.
What is the protein family that this protein belongs to?
Belongs to the paxB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BPT_PSEMY
Sequence: MTELARLKFYATQPHPCSYLPAEQATTLFLDPSQPMDVLVYAELSEMGFRRSGDHLYRPHCQQCTACIPARIPAALFTPNRQQRRILKRNEDVSVHPVRPAFTEEYYDLYVRYIEQRHADGDMYPPSRDQFSTFLVRDLPFSRFYEFRLAGRLVAIAVTDVLPNGLSAVYTFYDPAEERRSLGRFAILWQIGETARLGLGAVYLGYWIKNCRKMNYKTQYRPIELFVNQRWTLLT
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_AMOA5
Sequence: MASFDFIDEVKKYVQAGHGGPGVVHFRREKFVPKGGPDGGDGGKGGDIILKGNKQLSTLLHLKYRKHIVAEDGKSGEGGCRTGADGTSIILEVPLGTVAKDIDSGNILVDITEDGQQTILLHGGRGGQGNVHFKTPTQQAPRHAQPGESGEEGWIKLELKLLAEVGLVGFPNAGKSTLLASISAAKPKIANYPFTTLVPQLGVVAYREGHSFVLADMPGIIEGASMGKGLGTRFLKHIERNRVLVLMISADDTANIVQTYTSLLKELKSYSEDLFKKPRILVISKLDLIGAEEKVTIKKLLPKQIDCVFISSVTGEGLQKFKDKIWKLLHPELK
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_MYCA1
Sequence: MALTAEQKKEILGTYGLHDTDTGSPEAQVALLTKRIADLTEHLKVHKHDHHSRRGLLLLVGRRRRLLKYVAQIDVERYRSLVERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SEPF_MYCS2
Sequence: MSTLHKVKAYFGMAPMDDYEDEYYEDDDRGARAGGYSRRPREDRFEEEAYGYEGHEYDEGPAYRGGYAERFADEPRFEGRMRAPREFDRPAPARLGAMRGSTRGALAMDPRGMAELFEAGSPLAKITTLRPKDYSEARTIGERFRDGTPVIMDLVSMDNADAKRLVDFAAGLAFALRGSFDKVATKVFLLSPADVDVTAEERRRIAEAGFYSYR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RS15_SALG2
Sequence: MSLSTEATAKIVSEFGRDANDTGSTDVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HUTH_CAUVN
Sequence: MERPVTELVLNPGAVPLAEWKAIYRGASARLAESAWPVIAESAAAVQRILAKGEPVYGINTGFGKLASVRIGDADLETLQRNIVLSHAAGVGEPSPVPVIRLMMALKLASLAQGASGVRVETVRMLEEMLVEGLTPVVPCQGSVGASGDLAPLSHMAATMIGVGEIFVGGQRLPAAQALAQAGLEPLTLGPKEGLALLNGTQFSTANALAGLFEAERLFQSALVTGALSTEAAKGSDTPFDPRIHTLRRHVGQIETAAALRALMSASEIRASHLKEDERVQDPYCLRCQPQVMGAALDILRQAATTLATEANCVSDNPLIFPEADEALSGGNFHAEPVAFAADMIALAVCEIGSIAERRIAMLVDPALSGLPAFLTPKPGLNSGFMIPQVTAAALVSENKQRAYPASVDSIPTSANQEDHVSMAAHGARRLLAMVENADAVLGIELLAAAQGCDFHAPLRSSAALEAVRALTRSKVPHLSDDRHFHPDMEAANTLVRSGAVIAAVGALPGVTA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_METFK
Sequence: MHGEHDRGGVIIKVCDDVLALAGKHERAINLTKLDNTLEQHTPMMRQYLGIKAQYPDMLVFYRMGDFYELFHDDAEKASRLLGITLTKRGSSNGEPIRMAGVPYHAAEQYLAKLAKLGEAVAICEQVGDPAKSKGPVERQVTRILTPGTLTDAALLDDTRDNLLLAIAHGEGVLGLARINLASGRFILSEITPGLLAQELERISPAEILYPDDFYHMALEQVKCPKKRLAPWQFDLDSSIQTLTKQFSTYDLDGFGCAHMLAAIMAAGALLDYVKHTQRTSLPHIQSLMVEQGSQFIQLDAATRRNLEIDQTLRGESSPTLYSLLNTTVTAMGARLLRSWLHHPLQHQADIQARLQAVKVLQAQYDGLRPLLRNVGDIERMAARVALKTARPRDLSGLRDSLQQLPALQRVLRPEDSALLHSLQQQLDVPQAALDMLIAAIKDEPAAVLREGGVIADGFDAELDELRAIQSNCGEFLLQFEAQERERSGISNLKVEYNSVHGFYIEISRAQSENVPAEYRRRQTLKNVERYITPELKTFEDKVLSANERALAREKFLFDELLGNLQPALAAWQRNAEAVAQLDVLATFAERADVLKYVAPQFSSEAGLDIVDGRHPVVEQLAQPFIANSVSLSPYRQLLLITGPNMGGKSTYMRQTALIVLLAHCGCFVPAKSARIGPIDRIFTRIGASDDLAGGRSTFMVEMTETANILHNATERSLVLLDEIGRGTSTFDGLSLAWAVARQLLEKNRSYTLFATHYFELTRISEEFKHAANVHLDAVEHGDGIVFLHNVEEGPASQSYGLQVAQLAGIPRTVVNAAKRKLVQLEQSQVMQQSLAGQGDMFVAANVEPEPATHPVVSELESIDPDSLTPRQALDVLYKLKKLI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y1364_HAEIN
Sequence: MDKLNAISIFCKVIETQSFTLAAKQQNISVAMASKLVSQLEEHLKTRLLQRTTRKIMPTEAGMMYYQRCQGILLDLDEADSSITQLTSSLQGNLLISVPRDFGLLFIAPNLPTFMAKHPHLHIEVEFNDKKIDLLSEGYDLALRIGYMEDSSLVSRKIGTTTVHFAASPNYLETNGIPQTPDDLEHHNGLLYKNAMNQVNWVGSRINQTQRFKIQSKVVSNSGFALLNMAKAGLGIANLPKFILGRAFEKGELIEILPEYKQQKLEIHVVYPNRRHLPIKVTGISLNF
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator HI_1364, ORF2.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PROB_XANCP
Sequence: MLKVGSSLLAADGGGLSPRFALGLAQFVSANLAAGREVVIVSSGAVAAGRAILPKAAEAGAAIAARQALAALGQAQLIALWQRFFERPVAQVLLTHDDLRNRRRYLNARATLGELLRLGALPVINENDTVSVDELKLGDNDNLAAIVAALVDADALFIATDIDGLYSADPRSNPLARPLDEVAELSAEVLAMAGGSGSSVGTGGMRTKLEAAAKAGAAGIETYLFNGRSAEVVRGLAQDRLCGTRIHAARTRIAARKYWLRHAPVEPGTILIDAGAALALTDKGASLLPGGVAGAEGDFRRGDMVEIHLRDSVGSRCLARGVSQYSALDVRRIARRHSREIEPILGYSYGENVVHRDDLVVL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHJP_BACSU
Sequence: MKLIEHYVALVKTGCAEYGQMNEMTLTEIADCLFCTERNAKLILHKLENSNWIIRESGAGRGRKSKIAFLRRPEELLLQTAKEYTMSGKLKKAKELLQQYQSAFPGLQNEYNMWLSEVFGFVTETGENGAKDVLRLFITPESVSSLDPCQIFLRSEGHFVKQIFDTLFTFDSDMQEPKPHLVHGWEEVGKKQWRFFLRKGVLFHNGQPLTSRDVAFTFQRFLELADNPYKWLLHGVKQVLEKGPYCVELILDKPNALLPYALCDERLSILPAEQGGGKNGTGPFQMNQQHSGMLVLEANERYFKGRPYLDRVEFVFSEQAGEMNGFTIQEKQTCPEQQTVFDERHVQYLSLNLKKKGPLQHRSFRKALRLLISSERLVREAGGHRRIPVTSFLHPSPFEWEGVSPSELLKKSGYEGETIVLYTFSETDHREDAEWIQNICAQHGIRLTLQFCDAADLRRPEIVQMADIIHDSATFYQDSEFGFLHLLLSENSFLYQHLSEKLTQICSGMTERMFSMPDRCSRINILRDIDRQMIQELNAIPLYQNVLQVTSSKNVKGLVLDEEGWIDLYSVWLSK
What are the official names of this protein?
Uncharacterized protein YhjP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the bacterial solute-binding protein 5 family.
Protein: UREG1_SACEN
Sequence: MLPEHHDHGHEHGGNGHGHGHRHQVNFDPTAAEPDPYGVAPRGGRAFRLGIGGPVGSGKTALTAALCRALGSEVNLAVVTNDIYTTEDADFLRRAGVLDTDRIEAVQTGACPHTAIRDDITANLDAVEKLEERHPGLELVIVESGGDNLTAVFSRGLADSQVFVVDVAGGDKVPRKGGPGVTTADLLVINKVDLAEQVGADMAVMVADAHRMRGELPVITQSLTRTPNAPDVSAWVRQQLAAGVVVGA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG 1.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG148_MONPV
Sequence: MTSSADLTNLKELLSLYKSLRFSDSVAIEKYNSLVEWGTSTYWKIGVQKVTNVETSISDYYDEVKNKPFNIDPGYYIFLPVYFGSVFIYSKGKNMVELGSGNSFQIPDEIRSACNKVLDSDNGIDFLRFVLLNNRWIMEDAISKYQSPVNIFKLASEYGLNIPNYLEIEIEEDTLFDDELYSIMERSFDDTFPKISISYIKLGELKRQVVDFFKFSFMYIESIKVDRIGDNIFIPSVITKSGKKILVKDVDHLIRSKVREHTFVKVKKKNTFSILYDYDGNGTETRGEVIKRIIDTIGRDYYVNGKYFSKVGIAGLKQLTNKLDINECATVDELVDEINKSGTVKRKIKNQSVFDLSRECLGYPEADFITLVNNMRFKIENCKVVNFNIENTNCLNNPSIETIYGNFNQFVSIFNTVTDVKKRLFE
What is the function of this protein?
Plays an essential role in viral DNA replication by acting as the polymerase processivity factor together with protein OPG116.  Serves as a bridge which links the DNA polymerase OPG071 and the uracil DNA glycosylase.
What are the official names of this protein?
DNA polymerase processivity factor component OPG148.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG148 family.
Protein: MTRH_METAC
Sequence: MFKFDRKQEVYEVGGVKFGGQPGEYPTVLVSTMFYARHKIVTDEDKGIFDRAAAETLWNTQVSLSDATGNPYVNQIVGETPESIRKYIDWFIEIDDKTPFLIDSSAGEVRAAAAQYCTEIGVANRAIHNSINASIEQSEIDILTESDVEAAIVLAFNATDPTVKGKLDILEVGGSGQTKGMLQVAEECGIKIPLIDVAAMPLGAGSGATIRSIPTIKGKLGLPVGGGYHNMASAWDWLRKFKKTQPDPKAIYMPADIGTNLVAQIAGSDFLLYGPIENVEKVFPAVAMVDIMLGETAKELGVEIADSENHPVTRLT
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.  MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit H, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit H.
What is the protein family that this protein belongs to?
Belongs to the MtrH family.
Protein: COXX_AZOC5
Sequence: MNENAGRSLAPQASEGLGTPRDYISLLKPRVMSLVIFTALVGLVRAPDHVHPVIAFTAILCIAVGAGAAGALNMWWDADIDAVMSRTQRRPIPAGRVTPREALAFGLTLAAFSVVVLGLLVNVLAGALLAFTIFFYVVVYTMWLKRSTPQNIVIGGLSGALPPMVAWAAASGSISLESVILVAIIFFWTPPHFWALSLYRADDYARAGVPMLPVTAGPDETRKQILLYTLFLVPLALSPVMLGEAGLAYGVVAGVTGLGMLLLAVNVYRRRTGPAAVTAAKKLFGFSILYLFLLFATLLAEALVRGM
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBP_METJA
Sequence: MKIMEPEIKIVNVVVSTKIGDNIDLEEVAMILENAEYEPEQFPGLVCRLSVPKVALLIFRSGKVNCTGAKSKEEAEIAIKKIIKELKDAGIDVIENPEIKIQNMVATADLGIEPNLDDIALMVEGTEYEPEQFPGLVYRLDDPKVVVLIFGSGKVVITGLKSEEDAKRALKKILDTIKEVQEL
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: KCNQ2_MOUSE
Sequence: MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTGGAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRPKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLTFRKEPQPEPSPSQKVSLKDRVFSSPRGMAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRTRQAFRIKGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRIDMIVGPPPPSTPRDKKYPTKGPTAPSRESPQYSPRVDHIVGRGPTITDKDRTKGPAETELPEDPSMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSRDHADKHGCIIKIVRSTSSTGQRNYAAPPAIPPAQCPPSTSWQQSHQRHGTSPVGDHGSLVLRLERSAGMMSCH
What is the function of this protein?
Associates with KCNQ3 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.  Therefore, it is important in the regulation of neuronal excitability (PubMed:12223552).  KCNQ2-KCNQ3 channel is selectively permeable to other cations besides potassium, in decreasing order of affinity K(+) > Rb(+) > Cs(+) > Na(+).  Associates with Na(+)-coupled myo-inositol symporter SLC5A3 forming a coregulatory complex that alters ion selectivity, increasing Na(+) and Cs(+) permeation relative to K(+) permeation (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily KQT member 2, KQT-like 2, Potassium channel subunit alpha KvLQT2, Voltage-gated potassium channel subunit Kv7.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.2/KCNQ2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THII_STRPC
Sequence: MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAIAVRSDRDRTHVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRDGLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAYISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPGALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIREQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTFDISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTKITPEIVNDEVENLIDALL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_PORPU
Sequence: MRLTQGAFSFLPDLTDQQINKQLAYIVSKGWSANVEYTDDPHPRNAYWELWGLPLFDVKDPAAVMYEINSCRKAKPSYYVKVNAFDNTRGVESCSMSFIVNRPANEPGFLLQRQDFEGRTMKYTLHSYATEKPEGARY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEPA_BDEBA
Sequence: MDPKYIRNFSIIAHIDHGKSTLADGLLSATGSLSDREKKDQFLDNMELERERGITIKAQTVCLDFKSKDGNMYQINLIDTPGHVDFSYEVSRSLAACEGAILVVDAAQGVEAQTLANVYLAMENNLEIIPVLNKIDLPSADPEGVAKQIEDTVGLDCTGIIHASAKEKIGITDILEAIVEKVPPPKADRSLTPRALIFDSWFDAYQGVVVLVRMVDGVIKKGDKIKFMATDRDYEVLRMGKYKPFPLMQDVLEAGEVGFIVCGIKDIRDVQVGDTVTSAKHPATQPLAGFQRIKPMVFAGIFPVVASEYENLKDALDKLCLNDSSLTFEVEKSAALGFGYRCGFLGLLHMEIVQERLEREFNLDLITTAPTVVYRITKTDGTEMMLENPSGMPVETQIAKFEEPYVKVTLHTPTDYIGGILKLCEDKRGIQQKMEYVTDKKVIIEYKLPMNEMVMDFYDRLKSISKGYASLEYEFVGFEESDLVKLDILINGEAIDALSLIVHRSKAQNRGRLLAEKMKELIPRQMYQVAIQAAIGAKIIARETLGAIRKDVTAKCYGGDISRKRKLLEKQKEGKKRMKAIGHVEVPQEAFLAILKVED
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARLY_BRUSU
Sequence: MSEQKSSNQMWGGRFASGPDAIMEEINASIGFDRKLYAQDIQGSLAHAAMLAKTGIIAAEDHKQIENGLKTIRKEIEEGKFTFSRKLEDIHMNIEARLAELIGPAAGRLHTARSRNDQVAVDFRLWVKQELEKTAAALKNLIEAFLERAEEHAATVMPGFTHLQTAQPVTFGHHCMAYVEMFGRDLSRVRDAIERMDESPLGAAALAGTGFPIDRHMTAKALGFREPTRNSLDSVSDRDYALEFLSLAAICAGHLSRLAEEIVIWSTPQFNFVRLSDAFSTGSSIMPQKKNPDAAELVRAKTGRINGSLVALLTIMKGLPLAYSKDMQEDKEQVFDAAENLELAIAAMAGMVRDLTVNVAAMKKAAGSGYSTATDLADWLVRTLGLPFREAHHVTGRAVALAESRKVDLAKLSLEELQSINPAITAEVFGYLTVEKSVKSRQSFGGTAPQEVRRQIRYWKKRIAKA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTD_ECO81
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLDQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVIGHALGALVGMQLALDYPASVTVLVSVNGWLRINAHTRRCFQVREQLLHSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSRHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACNVTAPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: AROE_STRPZ
Sequence: MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAFEVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGKGHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEVRLFNRQATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENLSLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLITGQDMPVDAIKPLLGDE
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CEP1_HCMVM
Sequence: MEALMIRGVLEVHTDFTRQNVMIMEPQVLDFTVRGDKLWLHTEHGLLVSMAEYRSELLCTSAFLGYSAVFLLETEDAVTQVRLSDLRLKHRCGIVKADNLLHFALCTVISCVENCNLTRKCLHDLLQYLDAVNVRESFGRLLHHSARRLICSALYLLFEEKEPHIVQYVPATFVLFQQTRHTCLQLVARFFFRLTGQDEAHSFSLKLTERKTVDGWPVGLGLLDVLNANYPNLPSPPKLPPRWERGEEE
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm.
What are the official names of this protein?
Cytoplasmic envelopment protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 1 family.
What are the subcellular locations of this protein?
Virion. Virion tegument. Host cytoplasm. Host Golgi apparatus.