PharMolix/UniProtQA huggingface dataset:
Protein: ENO_ALTMD
Sequence: MAKISRIIGREILDSRGNPTVEADVYLESGAMGRAAAPSGASTGSREALELRDGDKSRYLGKGVTKAVAAINDTISPALLGKDALAQADIDGIMIDLDGTENKETLGANAILAVSLAVAKAAAAEKGVALYEHIADLNGTSGQYSMPVPMMNIINGGEHADNNVDIQEFMVQPVGAKSFKEALRMGAEIFHALKKVLSAKGLNTAVGDEGGFAPNLSSNAEALAVIVEAVENAGYKMNEDITLALDCAASEFYKEGKYVLSGEDKSFDSEAFGDYLADLSAQYPIVSIEDGLDESDWDGWASLTKKIGDKVQLVGDDLFVTNTKILKRGIDNGIGNSILIKFNQIGSLTETLNAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLCRSDRVAKYNQLLRIEEALGDAATYKGRSEIKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: LRC52_MOUSE
Sequence: MSLASGPSSKLLLFSLGMGLVSGSKCPNKCVCQDQEVACIDLHLTEYPADIPLNTRRLYLNNNKITSLPALQLGFLSDLVYLDCQNNRIREVMDYTFIGIFRLIYLDLSSNNLTSISPFSFSVLTNLVRLNISHNPHLLYLDKYVFANTTSLRYLDLRNTGLHIIDHNGFHHLVVLQTLYLSGNPWICNCSFLDFTIHLLVSHMDHPDAQNATCTEPAELKGWPITKVGNPLQYMCITHLDQQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQNALRTSSGDDTEDETGSRFANQIFRSNTHLGPIRRFPELI
What is the function of this protein?
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha).  Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium (By similarity).  KCNU1 channel auxiliary protein.  May modulate KCNU1 gating properties, shifting KCNU1 gating to more negative potentials at a given pH.
What are the official names of this protein?
Leucine-rich repeat-containing protein 52, BK channel auxiliary gamma subunit LRRC52.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Expression at the cell surface may require the presence of KCNU1.
Protein: NU4LM_MACSY
Sequence: MIPTYMNIMLAFTISLLGMLTYRSHLVASLLCLEGMTMSLFIMTALIASNTHSPLINIMPIILLVFAACEAAVGLALLISISNTYGLDYIHNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COAE_SHEON
Sequence: MSKFVVGLTGGIGSGKTTVANLFAEEGICLVDADVVAREVVAPGTHGLNAIISHFGTEMLTASGELDRAKLRQRVFNDEQERQWLNQLLHPMIRQEMLLQVEKATSDYVIMVVPLLFENGLDRLVHRTLVVDISPELQISRTVQRDNVDATQVNNIINSQCSRSEKLARADDIIDNHGEISRLKREVHALHQRYLQLSGNHNAHD
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP187_ARATH
Sequence: MRWNKKNVISLVSKSHHLPAPITPPLPEIYRIPNPPPKLPEISIPPTLTLSPSPKHSNFVNFLENNLPHHQTLTPQTLLGFLRSKIRNHPLYAHYDFAVFNWAATLDTFRHDHDSFLWMSRSLAATHRFDDLYRLLSFVAANPCPCSSGIFSCPELEPIFRSAIDAYCRARKMDYALLAFDTMKRLIDGKPNVGVYNTVVNGYVKSGDMDKALRFYQRMGKERAKPDVCTFNILINGYCRSSKFDLALDLFREMKEKGCEPNVVSFNTLIRGFLSSGKIEEGVKMAYEMIELGCRFSEATCEILVDGLCREGRVDDACGLVLDLLNKRVLPSEFDYGSLVEKLCGENKAVRAMEMMEELWKKGQTPCFIACTTLVEGLRKSGRTEKASGFMEKMMNAGILPDSVTFNLLLRDLCSSDHSTDANRLRLLASSKGYEPDETTYHVLVSGFTKEGRRKEGEVLVNEMLDKDMLPDIFTYNRLMDGLSCTGKFSRKQVRML
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g36240.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: GLPK_LISMO
Sequence: MEKKYILALDQGTTSSRAMIIDEEGEVIGVAQEEFDQIFPKPGWVEHNANEIWASILAVIAGVLLKTNISSKEIAGIGITNQRETTVIWDKESGNPIYNAIVWQSRQTEDICKQLRKDGYEDTIRSKTGLLIDPYFAGTKARWILDHVDGAQERAEKGELLFGTIDTWLVWKLTGGRAHITDYSNASRTLLYNIYDLEWDDELLKMLNIPKAMLPEVRPSSEVYADTVPYHFFGEEVPVAGIAGDQQAALFGQGCFEKGMAKNTYGTGCFLLMNTGEKAVRSENGLLTTLAWGIDGKVEYALEGSIFVAGSAIQWLRDGLRMVRQSSDSENYASRIESSDGVYVVPAFVGLGAPYWDSDVRGAVFGLTRGTEKEQFIRATLESLAYQTRDVLYAMEQDSGISLKTLRVDGGASANNFLMQFQSDILGVPVERPENKETTVLGAAFLAGLAVGVWKDKNEIKKHWKLDKRFEVEMKEEQREDLYEGWHKAVKAAQAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: COPB2_ORYSJ
Sequence: MEKPSTLLVHFDKGSAAMAGEIKADLEGSDVAAKVDAMKRAVMLLLNGETLPTLFITVVRYVLPSEDHTIQKLLLLYLEIIDKRDAAGRGLPEMILICQNLRNNLHHPNEYIRGVTLRFLCRLSEPEVLEPLVPSILENLDHRHHFIRRHALSAISSIYRLPHGDQLVPDAPELVERALASEQDASARRNAFLMLCTCAQERAVAYLLSNADRVAEWPDLLQMAAVDLIRKVCRSPNRADKGRYIKIIIALLSSPSTAVVYECAGALVSLSSAPTAVRAAANTYCELLSSQSDNNVKLIVLDRLNELRTSHRDVMVDVVMDVLRALASPNLDVKRKVLDLVLDLLTARNVEEVVLYLKKEVVKTQAGELEKSGEYRQMLVQAIHACAVEYPEVAGSVVHLLMDFLGDTNVAAAVDVVLFVREIIETNPKLRVSMIQRLIDTFYQIRASRVCSCALWILGEYSLSLSEVENAISTIKQCLGDVPFYTVSEEGEATDSAKPAQPVVNSVTVSSRRPVVLADGTYATQSAATEAISTPSVAPGSLSSTLNLRSLILSGDFFLAAVISCTLTKLVLRLEEVQPSMVEVNKACTGALLVMTSILQLGQSSYLPHPIDNDSYDRIVLCVRLLCNTGDDVRKVWLQSCRQSFAKMLAEKQFRETEEMKAKAQISHAQPDDLIDFYHLKSRRGMSQLELEDEVQDDLKAATGGFTKDAYDANRLNRILQLTGFSDPVYAEAYVTVHHYDIVLDVTIINRTKETLQNLCLELATMGDLKLVDRPQNYTLAPESSKQIRANIKVSSTETGVIFGNIVYETSNVMERSVVVLNDIHIDIMDYISPATCADVTFRNMWAEFEWENKVAVNTVIQNEKEFLDHIIKSTNMKCLTPPSALDGECGFLAANLYAKSVFGEDALVNISIEKQFDGKLSGYIRIRSKTQGIALSLGDKITLKQKGGS
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit beta-2, Beta-coat protein 2, Beta-COP 2.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: CPDA_HAEIN
Sequence: MKNTFVYQAEKPVIKLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDVILATGDLVQDSSDEGYIRFVEMMKPFNKPVFWIPGNHDFQPKMAEFLNQPPMNAAKHLLLGEHWQALLLDSQVYGVPHGQLSQHQLDLLKETLGKNPERYTLVVLHHHLLPTNSAWLDQHNLRNSHELAEVLAPFTNVKAILYGHIHQEVNSEWNGYQVMATPATCIQFKPDCQYFSLDTLQPGWREIELHSDGSIRTEVKRIQQAEFFPNMQEEGY
What is the function of this protein?
Hydrolyzes cAMP to 5'-AMP.  Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.  May coordinate responses to nutritional stress, ensuring optimal competence development.
What are the official names of this protein?
3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, 3',5'-cyclic AMP phosphodiesterase, cAMP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-III family.
Protein: RRFM_BOVIN
Sequence: MALGLRCFRLVHPAFCNSLAALTRPVSEVTLQTVRGRQNDHGQCMAYAAVPVRHFATKKAKAKGKGQSQTRMNLNTALVEDIINLEEVDEEMKSVIEALKDNFNKTVNIRTSPGALDNITVVTADGKLPLNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKDSLRKVRTNAINKVKKSKDKASEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity).
What are the official names of this protein?
Ribosome-recycling factor, mitochondrial, RRF, Ribosome-releasing factor, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PPK1_XYLFA
Sequence: MSKSSPIEPVSASDVSQQFRDPGLYLNRELSQLDFNFRVLAQALDEQVPLLERLRFLCISCTNLDEFFEIRVATVRHAQEFGLPPAPDGMRPTVILNAVHDLTTKLVHDQYNCWNQVLCPALAALGVGVLSHNSWNARQKRWLRGYFRNEIMPVLSPLGLDPAHPFPKIFNKTLNIVVVLNGIDAFGRAGHLAIVRAPRSLPRIIELPQHLSRDGSQNFVFLSSVLSAFVGELFPGMVVRGAYQFRVTRNSELVVDEDEVENLALALRNELVTRGYRLAVRLEIAEDCPTPIVRTLLQNFGLQENAVYRINGPVNLSRVSQVYDMVLRPELKYPPFNPRTLRNSDHIFEIIAKGDVLLYHPYDAFTAVLDLLRQAAADPDVLAIKQTLYRTGKDSTIVDALIQAARSGKDVTVVVELRARFDEEANLGLADKLQEAGVQVVYGVVGYKTHAKMLLIVRREGRKLRRYVHLGTGNYHSGTARIYTDLSLMTANAAIGKDVHQLFLQLSGLAPKMKLECLLQSPFTLHAGVLFRIERETKFARKGRPARIVAKMNALNEPQVVRALYVASQAGVQIDLIVRGACTLRPGVQDISENIRVRSIVGRFLEHSRVYWFANNGTPELFCASADWLERNLLRRVEICFPILNPDLAKRIYSDVLQSYLDDNLNAWELGSDGVYRKLLPETDHAPYSAQVALLESL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: AAE15_ARATH
Sequence: MQIRLKPDYSFFIASSSTMASTSSLGPSTLLSYGSPSRQFPDFGFRLISGHESVRIPSFRRFRVHCESKEKEVKPSSPFLESSSFSGDAALRSSEWKAVPDIWRSSAEKYGDRVALVDPYHDPPLKLTYKQLEQEILDFAEGLRVLGVKADEKIALFADNSCRWLVSDQGIMATGAVNVVRGSRSSVEELLQIYRHSESVAIVVDNPEFFNRIAESFTSKASLRFLILLWGEKSSLVTQGMQIPVYSYAEIINQGQESRAKLSASNDTRSYRNQFIDSDDTAAIMYTSGTTGNPKGVMLTHRNLLHQIKHLSKYVPAQAGDKFLSMLPSWHAYERASEYFIFTCGVEQMYTSIRYLKDDLKRYQPNYIVSVPLVYETLYSGIQKQISASSAGRKFLALTLIKVSMAYMEMKRIYEGMCLTKEQKPPMYIVAFVDWLWARVIAALLWPLHMLAKKLIYKKIHSSIGISKAGISGGGSLPIHVDKFFEAIGVILQNGYGLTETSPVVCARTLSCNVLGSAGHPMHGTEFKIVDPETNNVLPPGSKGIIKVRGPQVMKGYYKNPSTTKQVLNESGWFNTGDTGWIAPHHSKGRSRHCGGVIVLEGRAKDTIVLSTGENVEPLEIEEAAMRSRVIEQIVVIGQDRRRLGAIIIPNKEEAQRVDPETSKETLKSLVYQELRKWTSECSFQVGPVLIVDDPFTIDNGLMTPTMKIRRDMVVAKYKEEIDQLYS
What is the function of this protein?
Probably involved in the activation of fatty acids to acyl-carrier-protein prior to fatty acid elongation in plastids.  Acts on medium- to long-chain fatty acids.
What are the official names of this protein?
Long-chain-fatty-acid--[acyl-carrier-protein] ligase AEE15, chloroplastic, Acyl-[acyl-carrier-protein] synthetase, Acyl-activating enzyme 15.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UPP_ARATH
Sequence: MACSIGNAFRCSSDTLRFAPRQQCSSRLNPNPSSFLSFNSSPILAQNLGASSSSLSRRTIRARTKMAASEASINGSNRMLVFVPPHPLIKHWISVLRNEQTPCPVFRNAIAELGRLLMYEASREWLPTVVGEIMSPMGPASVEFIDPREPIAVVPILRAGLALAEHASSVLPANKIYHLGVSRDEKTLLPSVYLNKLPDEFPKNSRVFLVDPVLATGGTIMAAMDLLKERGLSVQQIKVICAIAAPPALSKLNEKFPGLHVYAGIIDPEVNEKGYIIPGLGDAGDRSFGTETHWVK
What is the function of this protein?
Uracil phosphoribosyltransferase (UPRT) that catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.  Is probably the only functional UPRT, since the dual-domain proteins of the UKL family seem to lack this activity.
What are the official names of this protein?
Uracil phosphoribosyltransferase, chloroplastic, UPRTase, UMP pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AGO3_MOUSE
Sequence: MEIGSAGPIGAQPLFIVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSVKFVSRVSWHLLHEALAGGTLPEPLELDKPVSTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNFFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
What is the function of this protein?
Required for RNA-mediated gene silencing (RNAi).  Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them.  Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4 (PubMed:19174539).  Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (By similarity).
What are the official names of this protein?
Protein argonaute-3, Argonaute3, mAgo3, Argonaute RISC catalytic component 3, Eukaryotic translation initiation factor 2C 3, eIF-2C 3, eIF2C 3, Piwi/argonaute family protein meIF2C3.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: Y1136_ARATH
Sequence: MRIVACLLLITALFSSYGYAAITTSSPLSIGVTLSSPGGSYELGFFSSNNSGNQYVGIWFKKVTPRVIVWVANREKPVSSTMANLTISSNGSLILLDSKKDLVWSSGGDPTSNKCRAELLDTGNLVVVDNVTGNYLWQSFEHLGDTMLPLTSLMYDIPNNKKRVLTSWKSETDPSPGEFVAEITPQVPSQGLIRKGSSPYWRSGPWAGTRFTGIPEMDASYVNPLGMVQDEVNGTGVFAFCVLRNFNLSYIKLTPEGSLRITRNNGTDWIKHFEGPLTSCDLYGRCGPFGLCVRSGTPMCQCLKGFEPKSDEEWRSGNWSRGCVRRTNLSCQGNSSVETQGKDRDVFYHVSNIKPPDSYELASFSNEEQCHQGCLRNCSCTAFSYVSGIGCLVWNQELLDTVKFIGGGETLSLRLAHSELTGRKRIKIITVATLSLSVCLILVLVACGCWRYRVKQNGSSLVSKDNVEGAWKSDLQSQDVSGLNFFEIHDLQTATNNFSVLNKLGQGGFGTVYKGKLQDGKEIAVKRLTSSSVQGTEEFMNEIKLISKLQHRNLLRLLGCCIDGEEKLLVYEYMVNKSLDIFIFDLKKKLEIDWATRFNIIQGIARGLLYLHRDSFLRVVHRDLKVSNILLDEKMNPKISDFGLARLFHGNQHQDSTGSVVGTLGYMSPEYAWTGTFSEKSDIYSFGVLMLEIITGKEISSFSYGKDNKNLLSYAWDSWSENGGVNLLDQDLDDSDSVNSVEAGRCVHIGLLCVQHQAIDRPNIKQVMSMLTSTTDLPKPTQPMFVLETSDEDSSLSHSQRSNDLSSVDENKSSEELNASS
What are the official names of this protein?
G-type lectin S-receptor-like serine/threonine-protein kinase At1g61360.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LPFC2_ECO57
Sequence: MPIFQREGHLKYSFAAGEYQAGNYDSASPRFGQLDLIYGLPWGMTAYGGVLISNNYNAFTLGIGKNFGYIGAISIDVTQAKSELNNDRDSQGQSYRFLYSKSFESGTDFRLAGYRYSTSGFYTFQEATDVRSDADSDYNRYHKRSEIQGNLTQQLGAYGSVYLNLTQQDYWNDAGKQNTVSAGYNGRIGKVSYSIAYSWNKSPEWDESDRLWSFNISVPLGRAWSNYRVTTDQDGRTNQQVGVSGTLLEDRNLSYSVQEGYASNGVGNSGNANVGYQGGSGNVNVGYSYGKDYRQLNYSVRGGVIVHSEGVTLSQPLGETMTLISVPGARNARVVNNGGVQVDWMGNAIVPYAMPYRENEISLRSDSLGDDVDVENAFQKVVPTRGAIVRARFDTRVGYRVLMTLLRSAGSPVPFGATATLITDKQNEVSSIVGEEGQLYISGMPEEGRVLIKWGNDASQQCVAPYKLSLELKQGGIIPVSANCQ
What is the function of this protein?
Part of the lpfABCC'DE fimbrial operon.  LP fimbriae may participate in the interaction with eukaryotic cells by assisting in microcolony formation.  Could be involved in the export and assembly of the fimbrial subunits across the outer membrane.
What are the official names of this protein?
Probable outer membrane usher protein LpfC'.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: MKS1_HUMAN
Sequence: MAETVWSTDTGEAVYRSRDPVRNLRLRVHLQRITSSNFLHYQPAAELGKDLIDLATFRPQPTASGHRPEEDEEEEIVIGWQEKLFSQFEVDLYQNETACQSPLDYQYRQEILKLENSGGKKNRRIFTYTDSDRYTNLEEHCQRMTTAASEVPSFLVERMANVRRRRQDRRGMEGGILKSRIVTWEPSEEFVRNNHVINTPLQTMHIMADLGPYKKLGYKKYEHVLCTLKVDSNGVITVKPDFTGLKGPYRIETEGEKQELWKYTIDNVSPHAQPEEEERERRVFKDLYGRHKEYLSSLVGTDFEMTVPGALRLFVNGEVVSAQGYEYDNLYVHFFVELPTAHWSSPAFQQLSGVTQTCTTKSLAMDKVAHFSYPFTFEAFFLHEDESSDALPEWPVLYCEVLSLDFWQRYRVEGYGAVVLPATPGSHTLTVSTWRPVELGTVAELRRFFIGGSLELEDLSYVRIPGSFKGERLSRFGLRTETTGTVTFRLHCLQQSRAFMESSSLQKRMRSVLDRLEGFSQQSSIHNVLEAFRRARRRMQEARESLPQDLVSPSGTLVS
What is the function of this protein?
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Involved in centrosome migration to the apical cell surface during early ciliogenesis.  Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication.  Required for cell branching morphology.
What are the official names of this protein?
Tectonic-like complex member MKS1, Meckel syndrome type 1 protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: HSLO_STRP8
Sequence: MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGRTLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATGEVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNVLLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIYGDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQFNESDLEALINDKA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_FRATF
Sequence: MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDHLADGPTIQEANIRALESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVGIAQIFIAPPDASESTLKQISKLGSGYTYLLSRVGVTGTETAANMPVEDVLAKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVKIIQNNISNKQKMLNELTYFVKEMKAATLN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: XYLA_CERS4
Sequence: MTDFFAGIPQIRYEGEGSSNEFAFRHYNPDEVILGKRMEDHLRFAVAWWHSFAWPGGDPFGGQTFDRPWFGDTLDLAKLKADVAFEMFDILGAPFFCFHDADIRPEGATFAESKRNLEEIVDHIGIRMEGSKTKLLWGTANLFSHRRFMSGAATNPDPDVFAWSAATVKGCMDATMKLGGANYVLWGGREGYETLLNTDLTREAENAGRFLQMVVDYKHKIGFQGTILIEPKPQEPSKHQYDYDVATVYGFLKRFGLEKEVKLNIEQGHAILAGHSFEHELALAASLGILGSIDMNRNDYQSGWDTDQFPHNHPEMALAYYEILRAGGFTTGGTNFDAKIRRQSLDPEDLVLAHVGGMDTCARALKAAARLYEDGSLETARAARYAGWETPEAQAMLASSLEKIEARVLAEGINPEPRSGRQERLENLWNRFV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_CITK8
Sequence: MKICLVDETGAGDGALSVLAARWGLEHDENNPMALVLTTAHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADPEIGPWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLAPARQLATKRVVVKRPDYAPPLADIATPNAVVTKGHRFDIYTGTALVE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LLDD_ECOK1
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALGPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSACALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQVLGKELPAALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ASTE_BURMA
Sequence: MTSSADSGRDAAWLDDFLALTLAGDAPPAEAGECAARAVRWRWLGDGLLRLEPADAAQRMQSVLVSAGVHGDETAPIELLSTLVRDIARGALPLRCRLLVALGNPGAMRAGERYLDDDLNRLFGGRHAQLAASREAPRAAQLEAAAALFFSTAGRARGARWHIDMHTAIRTSVFEQFALLPHTGEPPTRTMFEWLGEAQIAAVLLHTTKGSTFSHFTAQACGALACTLELGKVMPFGANDLSRFAPADAAVRRLVSGRRDAPRGALPRAFTVVDQITKQSDALELFVANDVPNFTPFARGTLLARDGDYRYAVRHEQERIVFPNPSVKPGLRAGLLVIETTRDTHAALA
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: PYRG_CUPPJ
Sequence: MTKFVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFVSAKMRKSNNFTTGQIYESVIRKERRGEYLGKTVQVIPHITNEIQAFIERGAAASHDGKADVALVEIGGTVGDIESLPFLEAARQMSLRMGRNRCAFVHLTLVPFIASAGELKTKPTQHSVQKLREIGISPTALLCRADRPIPDDERAKISLFANIPQDAVISVWDADSIYKIPQMLNEQGLDRLICEELRLDPKPADLSMWQKLVNAQENPEHEITIGMVGKYVDLTESYKSLIEALRHAGMHTATRVNIEYIDSEELESGHLEVLAPLDAILVPGGFGKRGTEGKIRAIQYARENKVPYLGICLGMQLAVIEFARHVAGMTDANSTEFNLETEHPVVALITEWVDREGKVEQRSAESDLGGTMRLGAQRVPVKEGTKAASIYGAEVNERHRHRYEVNNHYVPTLENAGMVISARTPTENLPEMMELPGSMHPWFVGVQFHPEFTSTPRDGHPLFKAYVEAALAGQQRKGA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.