PharMolix/UniProtQA huggingface dataset:
Protein: F16PC_CLOBJ
Sequence: MTLYDENNLHIIKDNLRYLKLLSKQYPSISSASSEIINLQAILNLPKGTEHFISDVHGEYESFTHMLKNASGVIKRKIDDVFGTSLRECDKKNLATLIYYPEQKLDLIKKSEKNLEDWYKITLYRLIRLCQIVSSKYTRSKVRKSLPSDFAYIIEELLNEQGDRVDKQEYYNSIIETIIDIDRASEFIIAISNVIQRLVVDKLHIIGDIYDRGPGAEIIIEALSKHHSIDIQWGNHDIVWMGAAAGCEACIANVIRISLRYANLSTLEDGYGINLLPLATFAMDFYKEDNCENFKPRTIDKNLNETDIKLLSKMHKAISIIQFKLEGKIIKRRPEFKMEERLLLDKINIKEGTLNLNEKIYKLIDTNFPTLDKENPYELNERERDLVEKLTNSFINSEKLQRHIKFLYSNGSLYLKYNSNLLYHGCIPLNEDGSLKEVTLCKETLKGKSLLDKLDRLAREAYFFKKDPESKLYGMDMMWYLWCGPNSPLFGKKKMTTFERYFLDDKNTHKEQKNPYYKYRNDEKMCTMIFEEFELDADNSHIINGHIPVKTKEGENPIKANGKLLVIDGGFCKAYQPQTGIAGYTLIYNSYGLLLTSHEPFSSIHKAIVEGNDILSSTTILEHVSSRKRVLDTDSGEEIKKQIHDLEMLLVAYRKGLIKEENEANIRF
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: HSLU_HAEIN
Sequence: MSEMTPREIVSELDQHIIGQADAKRAVAIALRNRWRRMQLQEPLRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAMKLVRQQEIAKNRARAEDVAEERILDALLPPAKNQWGEVENHDSHSSTRQAFRKKLREGQLDDKEIEIDVSAGVSMGVEIMAPPGMEEMTNQLQSLFQNLGSDKTKKRKMKIKDALKALIDDEAAKLINPEELKQKAIDAVEQNGIVFIDEIDKICKKGEYSGADVSREGVQRDLLPLVEGSTVSTKHGMVKTDHILFIASGAFQVARPSDLIPELQGRLPIRVELTALSAADFERILTEPHASLTEQYKALMATEGVNIAFTTDAVKKIAEAAFRVNEKTENIGARRLHTVMERLMDKISFSASDMNGQTVNIDAAYVADALGEVVENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_ECO8A
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERILFRLPGVSDHEMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMN_PSEPG
Sequence: MTTSTGKINLLGLTQPEMEQFFDSIGEKRFRAGQVMKWIHHFGVSDFAAMTNVGKVLREKLEAVAEIRPPEVVSEDISADGTRKWVIRVASGSCVETVYIPTDDRGTLCVSSQAGCALDCSFCSTGKQGFNSNLTAAEVIGQVWLANKSFGTVPAKVDRAITNVVMMGMGEPLLNFDNVIAAMKIMMDDLGYGISKRRVTLSTSGVVPMIDELAKHIDVSLALSLHAPNDELRNKLVPINKKYPLKVLLESCMGYMSTLGGKRVLTVEYTLLKDVNDQPEHAAQMIELLRDVPCKINLIPFNPFPHSGYERPSNNAIRRFQDLLHHGGFNVTTRTTRGDDIDAACGQLVGQVNDRTRRSERYIAVRQLSADVELQDSAASH
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRVP_HOPST
Sequence: MIAFIVLLSLAAVLQQSSGTVDFASESSNKKDYQKEIVDKHNALRRSVKPTARNMLRMKWNSRAAQNAKRWADRCTFAHSPPHTRTVGKLRCGENIFMSSQPFAWSGVVQAWYDEVKKFVYGIGAKPPGSVIGHYTQVVWYKSHLLGCASAKCSSTKYLYVCQYCPAGNIRGSIATPYKSGPPCADCPSACVNGLCTNPCKHEDDFSNCKALAKNSKCQTAWIKSKCPATCFCHNKII
What is the function of this protein?
Blocks olfactory (CNGA2) and retinal (CNGA1) CNG channel currents.  Does not affect neither depolarization- nor caffeine-induced contraction of smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein pseudechetoxin-like, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: PBL1F_EUGGR
Sequence: MYILVWKKGQQIKTFHTLDEAAQFKAASNIDEAQVFSVTDAPDISASGGSNEARNRRRLMYLTNSTNPEECNPQFVGEMARVATIQNREIGARGFLMYSCRFLLQVIEETVEDPDSLFAKFSPEPRHERWIELDNGPCTGRMYGDWNMKDSHLDSITTHPAMLTILFQMARSISCLWSYLQKSERIMLLFGKDPGAQRPEPMRVVVTFTYLVDFGSMLSIPNLTEQAAEVLTTFVDGCVKNVEGSGGSIAKFTTGICMAQWPINRTVEALTAIQQISEDLAQLRSQQAPGSAVSLMYSQAGLHYGRGMLCNAGSRKSDFTLLDFINTTSRIATLANKLKTPLLFHSFDVRCLLGDEMREEIEGAGMHQVKGRDKPVGVYQFPGPELDVEMVLRQKVEQFTPGRFRCQMPVVEYEALPIWQRPPIVDDTPKGYPRPRTMPGYGGRQRSDSLVDRLIMIAKLAGPSVSATGDTTLTTLTYISQATRKPMSRLHLSALMGTATRRNAQQSITGTLLDVNGLFGQTLEGPKVAVVMYLSIRQDARQTDVTTVHMAPLQERVCPSEWTLTSATEEMLATFPPLQDVLSQLAKSCTSLETYVRSTVGYLTAGNNRRNLMPVSCGVVMLATDIGSFTSLTEESSLTEVWMICNTFIDACTSAVCQEGGEVIKRIGDCVTAYFPGNNAESAVAAAQELFTFCRQLREAFVDVVDVRGCVSCGVGLDYSQVVMAQCGSLGLTEYVVAGVSARVMEVDAMTREVGYAIGVTEPYVTDRLSPQSRDHGIVPTPQAIELPCYGIAGEQLELDVDSIKRGIKALHAARSGEMPVTEPEEALRLFRVSPGRVRHGDTGRRSNSAQGKRSIQVR
What are the official names of this protein?
Photoactivated adenylate cyclase subunit beta-like protein 1224-5/1F.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=Paraxonemal body. And paraxonemal bodies (PABs).
Protein: IPCS2_ARATH
Sequence: MTLYIRRESSKLWKRFCSEISTEIGLLAENWKYLLAGLICQYIHGLAAKGVHYIHRPGPTLQDLGFFLLPELGQERSYISETVFTSVFLSFFLWTFHPFILKTKKIYTVLIWCRVLAFLVACQFLRVITFYSTQLPGPNYHCREGSKVSRLPWPKSALEVLEINPHGVMYGCGDLIFSSHMIFTLVFVRTYQKYGTKRFIKLFGWLTAIVQSLLIIASRKHYSVDVVVAWYTVNLVVFCLDKKLPELPDRTAVLLPVISKDRTKEENHKLLNGNGVDPADWRPRAQVNGKIDSNGVHTDNTMNGA
What is the function of this protein?
Catalyzes the transfer of the phosphorylinositol group from phosphatidylinositol (PI) to phytoceramide, an essential step in sphingolipid biosynthesis (PubMed:19001565, PubMed:20309609).  May play an important role in modulating plant programmed cell death (PCD) associated with defense (e. g.  toward Golovinomyces cichoracearum) by promoting sphingolipid metabolism and thus regulating ceramide accumulation (PubMed:19001565).
What are the official names of this protein?
Phosphatidylinositol:ceramide inositolphosphotransferase 2, Inositol-phosphorylceramide synthase 2, AtIPCS2, IPC synthase 2, Protein ENHANCING RPW8-MEDIATED HR-LIKE CELL DEATH 1, Sphingolipid synthase 2.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: RS11_TREDE
Sequence: MATVKKRKEKKSIYEGNVYIQATFNNTIITITDLKGNVLSWASSGGLGFAGAKKSTPFAAQTVAETAVQKCQPYGLHEVHVFVKGPGVGRESAIRTLGTMGLKVRSISDVTPIPHNGCRPKKTRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HISQ_SALTI
Sequence: MLYGFSGVILQGAIVTLELALSSVVLAVLIGLVGAGAKLSQNRVTGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNVVTDSLGIDQIDIDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTHGQTFRRIMFPAMMRYALPGIGNNWQVILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGLIYLVFTTVSNGVLLLLERRYSVGVKRADL
What is the function of this protein?
Part of the histidine permease ABC transporter.  Also part of a lysine/arginine/ornithine transporter.  Probably responsible for the translocation of the substrate across the membrane.  Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity).
What are the official names of this protein?
Histidine transport system permease protein HisQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAQRB_RAT
Sequence: MQFRNRFQRFMNHRAPANGRYKPTCYEHAANCYTHAFLIVPAIVGSALLHRLSDDCWEKITAWIYGMGLCALFIVSTVFHIVSWKKSHLRTVEHCFHMCDRMVIYFFIAASYAPWLNLRELGPLASHMRWFIWLMAAGGTIYVFLYHEKYKVVELFFYLTMGFSPALVVTSMNNTDGLQELACGGLIYCLGVVFFKSDGIIPFAHAIWHLFVATAAAVHYYAIWKYLYRSPTDFIRHL
What is the function of this protein?
Is involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion.
What are the official names of this protein?
Monocyte to macrophage differentiation factor, Macrophage/microglia activation-associated factor, MAF, Progestin and adipoQ receptor family member 11, Progestin and adipoQ receptor family member XI.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Protein: CSNB_ASPOR
Sequence: MRLSEILAVALVTGATAYDLPDNLKQIYEKHKGKCSKVYQKGFTNGGHSDGKSFEYCGDIEGAIFMHSSAKGGQYTNMDVDCDGANNSAGKCSNDPSGQGVTAFKDEVKKFGIPDLDANLHPYIVFGNEEHSPQFKPQKYGMEPLSVMAVVCNGKLHYGIWGDTNGGTSTGEASLSMAELCFPEEKPDGDHGHDDNDVLYIGFTGKDAVPGKSANWKAKKTEDFEDSIKSIGDKLVAGLKA
What is the function of this protein?
Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin.  Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.  Chitoolisaccharides produced by the hydrolysis of partially N-acetylated chitosan are known to have many biological activities, including antibacterial activity, immune-enhancing effects, and elicitor activity (By similarity).
What are the official names of this protein?
Endo-chitosanase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 75 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPP_YERPY
Sequence: MNEQYSAMRSNVSMLGTLLGDTIKEALGEHILDRVETIRKLSKSSRAGNEASRQELLTTLQNLSNDELLPVARAFSQFLNLTNTAEQYHSISPHGEAASNPEALAQLFTRLKDKKLSDQDMRSAVDDLSIELVLTAHPTEITRRTLIHKLVEVNTCLSQLDHNDLADYERNKIMRRLRQLVAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWEGVPAFLREFNEQLENSLDYRLPVEAVPIRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKATDLFLRDIQVLVSELSMSECTPELRELAGGEEVLEPYRQLMKNVRTQLTNTQAYLEARLKGERVLPPHDLLVSNDQLWEPLYACYQSLKACGMEIIANGQLLDTLRRVRCFGVPLVRIDVRQESTRHTDAIAELTRYLGLGDYESWSESDKQAFLVRELNSKRPLVPLKWEPSAETQEVLETCRVIAEAPQGSIAAYVISMAKVPSDVLAVHLLLKEAGCPFTLPVAPLFETLDDLNNADDVMTQLLGIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYRAQDALIKTCEKAGITLTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKFGLPEVTISSLALYAGAILEANLLPPPEPKKEWIEVMDLLSDASCDMYRSYVRENPEFVRYFRAATPELELGKLPLGSRPAKRRPDGGVESLRAIPWIFAWTQNRLMLPAWLGAGAGLQRAIDAGKRDVLATMCRDWPFFSTRIGMLEMVFAKADLWLAEYYDQRLVDKSLWPLGQQLRDQLAADIKVVLAIANDDHLMADLPWIAESIALRNVYTDPLNVLQAELLHRSRQQEHPDACVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: SEPT8_MOUSE
Sequence: MAATDLERVSNAEPEPRSLSLGGHVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEASHHEECVRLRPQTYDLQESNVHLKLTIVDAVGFGDQINKDDSYRPIVDYIDAQFENYLQEELKIRRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHKFKIKIMGELVSNGVQIYQFPTDDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVRARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRIHQEEKRKVEEKRRELEEETNAFNCRKAAMEALQSQALHATSQQPLRKDKDKKN
What is the function of this protein?
Filament-forming cytoskeletal GTPase (By similarity).  May play a role in platelet secretion (By similarity).  Seems to participate in the process of SNARE complex formation in synaptic vesicles (By similarity).
What are the official names of this protein?
Septin-8.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Synapse. Cell projection, axon. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Presynapse. Note=Expressed in axons of immature neurons, localizes to synapses in mature neurons.
Protein: PRSKL_PINFU
Sequence: MKGFLTLLLVCAILSTGYCQSRRRAALTGLVAGATIGALASGGLGAGAGGFGVGGFPVGVGAVGIPVAVGGGIPYGYGGYSGYGYGYPAGGYGGYSYGYPTGGYGGYSYGYPTGGYGGYSYGYPTGGYGGYSYGYPTGGYSGYSYGYPTGGYSGYSYGYPTGGYSGYSYGYPTGGYSGYSYGYPTGGYSGYSYGYPTGGYSGYSYPTGGYSGYSYSSTPGYGYYGSGSGMGGMRSGYSYYSSPAPSYYSSGSMTPGYGYYSSGSGIGGGMGSGYSYYSSPAPSYYSSSVSPGYGYYGSGSGMRGYGYYSSSTPMYYGSRSTGYGPFSSGLGGMGSGYSYYSSSTPSYYSSGSMTPGYGYYGSTSYPGPGYGSYSYRTTSYQPSSYGYSSYGTTYPGHGHWHGHKDC
What is the function of this protein?
Binds chitin and may serve as a framework constituent participating in shell formation.  Inhibits aragonite precipitation and may regulate aragonite growth during shell layer formation.  Does not affect calcite crystallization.
What are the official names of this protein?
Prisilkin-39.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYCP3_MOUSE
Sequence: MLRGCGDSDSSPEPLSKHLKMVPGGRKHSGKSGKPPLVDQPKKAFDFEKDDKDLSGSEEDVADEKAPVIDKHGKKRSAGIIEDVGGEVQNMLEKFGADINKALLAKRKRIEMYTKASFKASNQKIEQIWKTQQEEIQKLNNEYSQQFMNVLQQWELDIQKFEEQGEKLSNLFRQQQKIFQQSRIVQSQRMFAMKQIHEQFIKSLEDVEKNNDNLFTGTQSELKKEMAMLQKKVMMETQQQEMANVRKSLQSMLF
What is the function of this protein?
Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (PubMed:11311943, PubMed:22761579).  Required for centromere pairing during meiosis in male germ cells (PubMed:22761579).  Required for normal meiosis during spermatogenesis and male fertility (PubMed:10678170).  Plays a lesser role in female fertility (PubMed:10678170, PubMed:12004129).  Required for efficient phosphorylation of HORMAD1 and HORMAD2 (PubMed:22346761).
What are the official names of this protein?
Synaptonemal complex protein 3, SCP-3.
What is the protein family that this protein belongs to?
Belongs to the XLR/SYCP3 family.
Protein: 6PGD_BUCAI
Sequence: MSRQQIGVVGMAVMGRNLALNIESKNYSVSIFNRTRSVTEEVFNQNKKKNIVPYFSIKDFIDSLLKPRCILLMVQSGKATDETIKMILPYLEKEDILIDAGNTFYKDTIRRNEKLSKYEINFIGMGVSGGELGALNGPSIMPGGQKEAYKLVLPMLEKISAKFKGEPCVSYIGPNGAGHYVKMVHNGIEYGDMQLISESYFLLKYLLNMSNEELSSTFSKWNKGELNSYLIEITKNIFIEKDEKGKYLIDRILDVAEDKGTGKWISKSALDLREPLSLITESVFARYLSSLKRQRIIASKILQGPKIKTFIKDKNSFIEEVRRALYLGKIISYAQGFSQLKRASEKYHWNLKYGEIAKIFRAGCIIRANFLQKITDEYTQNKNVVNLLLTPYFSKIANEYENSLRNIVMYAIKYGISTPTFSAAISYYDSYRALYLPANLIQAQRDYFGSHTYQRTDQTGYFHTNWSQ
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: MNTH_STAAE
Sequence: MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMB_SALTI
Sequence: MSEMIYGIHAVQALLERAPERFQEAFILKGREDKRLLPLIHALESQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIALHDRPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLARTMRMLQEENIWIVGTAGEADHTLYQSKMPGRMALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVRQRT
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APHA_SALTI
Sequence: MKKITLALSAVCLLFTLNHSANALVSSPSTLNPGTNVAKLAEQAPVHWVSVAQIENSLTGRPPMAVGFDIDDTVLFSSPGFWRGKKTYSPDSDDYLKNPAFWEKMNNGWDEFSIPKEVARQLIDMHVRRGDSIYFVTGRSQTKTETVSKTLADNFHIPAANMNPVIFAGDKPGQNTKVQWLQEKNMRIFYGDSDNDITAARDCGIRGIRILRAANSTYKPLPQAGAFGEEVIVNSEY
What is the function of this protein?
Dephosphorylates several organic phosphate monoesters including monophosphate nucleotides (NMPs), coenzyme A (CoA), nicotinamide adenine dinucleotide phosphate (NADP), flavin mononucleotide (FMN) and phosphorylated 5-6 carbon sugars in vitro (PubMed:25848029).  Also has a phosphotransferase activity catalyzing the transfer of low-energy phosphate groups from organic phosphate monoesters to free hydroxyl groups of various organic compounds (By similarity).
What are the official names of this protein?
Class B acid phosphatase, CBAP.
What is the protein family that this protein belongs to?
Belongs to the class B bacterial acid phosphatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CATS_MOUSE
Sequence: MRAPGHAAIRWLFWMPLVCSVAMEQLQRDPTLDYHWDLWKKTHEKEYKDKNEEEVRRLIWEKNLKFIMIHNLEYSMGMHTYQVGMNDMGDMTNEEILCRMGALRIPRQSPKTVTFRSYSNRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKATDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI
What is the function of this protein?
Thiol protease.  Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation.  The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
What are the official names of this protein?
Cathepsin S.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Secreted. Cytoplasmic vesicle, phagosome.
Protein: BAT15_CAEEL
Sequence: MVAASKEFVFHHTFKDVSQLEDGDFFKSPEEIHYNAEWFILVIRTKDQLEAYLHCDNEKDDNVAWTVDAEFSLKIASSSGSYAMKFQKGCFDGFGLGWNDFVSWDSLTEDFLYDNSFTIEACVKITKMTGFSKDVLRSFDESEKRFSDVILVVGDEKFYVLKLFLASHSSYFNALFLGKFKEADQSEVTLQNIDPTDFQSLLEVLYGEPAIDDGTIDGVLLLAHMLDVTLAIRKCEEFLIEKSMKSMRELLKMANQYQLENLKTVCISKINTI
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB and MATH domain-containing protein 15.
Protein: EX7L_PECCP
Sequence: MSQFPSSAIFTVSRLNQTVRQLLEMEMGQIWLSGEISNLSQPSSGHWYFTLKDERAQVRCAMFRTSNRRVTFRPQNGQQVLIRATITLYEPRGDYQLLAESMQPAGDGLLQQQFEQLKQKLAAEGLFDQQFKQVLPSPAKQVGVITSASGAALHDILQVLQRRDPSLPVIVYPTSVQGADAPLQIVRAIELANQREECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHETDVTIADFVGDLRAPTPSAAAELVSRNQLELLRQIQSQRQRLEMAMDYYLAQRNREFTRLHHRLQQQHPQLRLARQQAQLVKLRQRLDDAMQQQLRQTLRRSERLQQRLMQQQPQTRIHRAQQRLQQLSYQMQSAVERQLNQNKQKLGIACSRLEGVSPLATLARGYNVTTAPDGKVLKNVTQITPGETLKTRLQDGWVESQVTTLVPNPSSVKKRRKPSSQS
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLTC_LACDA
Sequence: MDIQKQIVDILAEATGEDFSDNMDQELYESGIMDSMTTVQMLLTLQETFDITVPVSEFNRDDWNTPNKLVEQVKKLQDEE
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHE_PASMU
Sequence: MTQYNKLRIEWDCRRGMLELDNVIMPFYRQHFDALSDTQKDTFIRLLACSDLQLFSWFFNRGMATDPQLQQMVDYIQKTLKLTD
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YK14A_YEAST
Sequence: MNDHKLVFWVRSLRVTVNLFWSTVSSPSSMRNTTMRDKSNVSVRILLSNLLFQSTHFTDLLIDESRISFVTIDSNTGGIIASIF
What are the official names of this protein?
Uncharacterized protein YKL104W-A.
Protein: YPT35_YEAS7
Sequence: MNDKISFLPPEPIQLLDEDSTEPELDIDSQQENEGPISASNSNDSTSHSNDCGATITRTRPRRSSSINANFSFQKAHVSDCTIVNGDHGTKFAVWRITVFLEPNLKAFAAKRESYKIQTYKRYSDFVRLRENLLTRIKTAKPEKLNCLQIPHLPPSVQWYSSWKYQEVNLNKDWLAKRQRGLEYFLNHIILNSSLVEMTKDILIQFLEPSKRVA
What is the function of this protein?
Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
What are the official names of this protein?
Endosomal/vacuolar adapter protein YPT35, PX domain-containing protein YPT35.
What is the protein family that this protein belongs to?
Belongs to the YPT35 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.