PharMolix/UniProtQA huggingface dataset:
Protein: RL5_ECOBW
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL4_ALKOO
Sequence: MPKVAIYNVSGQQVSEIELSENVFGVEVNEHAMYEVVKNQLANRRQGTQSAKTRAEVRGGGRKPWKQKGTGRARVGSIRSPLWVGGGIVFAPKPRDYSYTIPKKVRRLALKSALTSKVNSNELIVLDELKLDAPKTKEMVNILKNLNVDKKALIVMGEKSEAVIKSANNIQGVQTALVNTINVYDILKYDKLIITKDAVQKVEEVYA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SUCC_SHESH
Sequence: MNLHEYQAKALFAEYGLPVSEGFACDTPQEAVEAAGRIGGDMWVVKCQVHAGGRGKAGGVKVTGSKDEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALFRQEKIRDMHDPSQDDAREAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVTVPVVVRLEGTNADLGRDVLASSDLDIIAATSLTDAAEQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RS19_METNO
Sequence: MARSVWKGPFVDGYLLKKAEAARGSTRSEVIKIWSRRSTILPQFVGLTFGVYNGQKHIPVYVSEEMVGHKFGEFSPTRTFHGHAADKKAKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CDGT_BAC11
Sequence: MKKISKLTTALALSLSLALSLLGPAHAAPDTSVSNKQNFSTDVIYQIFTDRFSDGNPANNPTGPAFDGTCTNLRLYCGGDWQGIINKINDGYLTGMGVTAIWISQPVENIYSVINYSGVNNTAYHGYWARDFKKTNPAYGTIADFQNLIAAAHAKNIKVIIDFAPNHTSPASLDQPSFAENGKLYNNGRDEGGYTNDTHNLFHHNGGTDFSTTENGIYKNLYDLADLNHNNSTVDTYLKDAIKMWLDLGIDGIRMDAVKHMPFGWQKSFMATVNNYKPVFTFGEWFLGVNEVSAENHKFANVSGMSLLDFRFAQKVRQVFKDNTDNMYGLKSMLEGSATDYAQMEDQVTFIDNHDMERFHNNSANRRKLEQALAFTLTSRGVPAIYYGTEQYMSGGNDPDNRARIPSFSTTTTAYQVSKKLAPLRKSNPAIAYGTTQERWINNDVLIYERKFGNNVAVIAVNRNVNTSASITGLVTSLPAGSYTDVLGGLLNGNNLTVGSGGSASIFTLAAGGTAVWQYTTAVTAPTIGHVGPMMAKPGAAVTIDGRGFGATKGTVYFGTTAVTGANITAWEDTQIKVKIPAVAGGVYNIKIANSAGTSSNVHDNFEVLSGDQVSVRFVVNNATTALGQNVYLAGSVSELGNWDPAKAIGPLYNQVIYQYPTWYYDVTVPAGKTIEFKFLKKQGSTVTWEGGSNHTFTAPTSGTATINVNWQP
What are the official names of this protein?
Cyclomaltodextrin glucanotransferase, Cyclodextrin-glycosyltransferase, CGTase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARLY_ECODH
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLPLSELQKFSQVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1556_CLOPS
Sequence: MKKNKLSIKTIVAIGIGSAVFMILGRFGSLPTGIPNTNIETAYAFLSLMALLYGPLAGFLIGFIGHALKDIVFFGSPWISWVFASGIVGLIIGFGARFIKINQGVFKLKQIFMFNLIQIIANGVAWFLVAPTLDILIYSEPLNKVYLQGVIGGISNMITVGVLGTVLISNYSKTRIKKGSLRKEY
What are the official names of this protein?
UPF0397 protein CPR_1556.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AQN3_PIG
Sequence: AQNKGSDDCGGFLKNYSGWISYYKALTTNCVWTIEMKPGHKIILQILPLNLTCGKEYLEVRDQRAGPDNFLKVCGGTGFVYQSSHNVATVKYSRDSHHPASSFNVYFYGIPQGAKA
What is the function of this protein?
AQN proteins mediate the binding of boar spermatozoa to component(s) of the egg's zona pellucida by a carbohydrate-binding mechanism.  AQN proteins are secretory components of the male accessory glands being coated to the sperm surface at the time of ejaculation.  They possess as well heparin-, serine-protease-inhibitor-binding capability.
What are the official names of this protein?
Carbohydrate-binding protein AQN-3, Spermadhesin AQN-3, Zona pellucida-binding protein AQN-3.
What is the protein family that this protein belongs to?
Belongs to the spermadhesin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3H_ASPFC
Sequence: MAENETPLTAVKVEALVVMKIMKHCSQTFPTTATGSIVGMDVGGTLEITNSFPFPVVEVPPESHFDNAAANPAAAAPRAKANTVYQAEMIRMLREVNVDANNVGWYTSANMGNFVNMNVIENQFFYQKEMNERTVALVHDVSRSSQGSLSLRAFRLSPKFMTAFKENKFTSEELQKSGLRYQDIFVELPVEIHNSHLITSFIHQLQTPNIPAPTELPSSLAALESGPFVKSSILAPNFDNLALSIDPFLEKNCDLLLDSIETHHTETNNFQYYQRSLAREQQRISAWQQKRKQENATRAALKQPLLPEDEWQRLFKLPQEPSRLESMLNSRQVDQYARQIDSFVSSTTGKMFAVKGNLLPGETAK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBY_SYNP2
Sequence: MDWRVVVVLAPVIIAGSWAIFNIAAAALNQLRNMQTKK
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RS3_BLOPB
Sequence: MGQKVHPNGVRLGITKTWHSTWYANNKDFSDNLGNDFKVRHFLMQKLSKALVSRIIIERPAKSIRVTVYTARPGLIIGKKGEDIEKLRKNIARISGVPTQLNIAEVRKPELDAKLLADNIASQLERRVVFRRAMKRVVQNAMRLGAKGIKVEVSGRLSGAEIARTEWYREGRVPLHTLRADIDYSLSEARTTYGIIGIKVWVFKGEILGDVLLLNTGYSSDQTINNSSKKKHKTRI
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: VSR_RDVO
Sequence: MEVDTATFVRLHHELLCAHEGPSIISKFDAIKKVKLGTLANQSGGANNITEAFLAKLRNFERKSEAYLASDLAERELTRDTHKAIVFVTKSVLLGGKSLKDLLPYGVIVCAFIFIPETASVLDNVPVMIGNQKRPLTVALIKYIAKSLNCDLVGDSYDTFYYCNSSAYGKNLISVSDNDFSNPQRALLSVGDLCYQAARSLHVAAANYIRIFDRMPPGFQPSKHLFRIIGVLDMETLKTMVTSNIAREPGMFCHDNVKDVLHRIGVYSPNHHFSAVILWRGWASTYAYMFNQEQLNMLSGTSGLAGDFGKYKLTYGSTFDEGVIHVQYQFVTPEVVRKRNIYPDLSALKGGSS
What is the function of this protein?
Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Suppressor of RNA-mediated gene silencing, Non-structural protein 10, Pns10.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus non-structural protein 10 family.
Protein: DBH1_RHILE
Sequence: MNKNELVSAVAEKAGLTKADAASAVDAVFETVQSELKNGGDIRLAGFGSFSVSRREASKGRNPSTGAEVDIPARNVPKFSAGKGLKDAVNS
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HRL18.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: AROE_ECO27
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVFRAEELAKLFAHTGSIQALGMDKLEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKLLQQELSA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: 143BA_DANRE
Sequence: MDKSDLVQKAKLAEQAERYDDMAASMKAVTEGGVELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEGNEKKQQMAREYREKIEAELQEICNDVLGLLEKYLIPNASQAESKVFYLKMKGDYYRYLSEVASGDSKRTTVENSQKAYQDAFEISKKEMQPTHPIRLGLALNFSVFYYEILNTPEQACSLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner (By similarity).
What are the official names of this protein?
14-3-3 protein beta/alpha-A.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STLP1_ORYSJ
Sequence: MKRPLRRPFAVLLFVVLCAAASFPSVLRRSVGPAPVLAPLPPLDPARLNATLLRLAAADPSEAPLRRDVDDLLEGRLPASSARARAWRLRGDRLHLHLRHHQFPVYRRGHHPDHDHDPLLHPLPRQELHLDPSLRRALRSWHRLRRHDPGVLRNLPSLLSLPGRIPSCAVVGNSGILLGASHGALIDSHAAVFRLNNARISGFAANVGAKTNLSFINSNVLHLCARRPNCFCHPYGDGVPILLYICQAAHFLDVASCNASSRSLHAASISVTDPRLDVLCARIVKYYSLRRFVAETGRAAEEWSSTRDAAMFHYSSGMQAIMVAVGVCDRVSVFGFGKAADAKHHYHSNQKAELDLHDYKAEYAFYRDLADRPEVVPFLNDAGIAVPPVVFYH
What is the function of this protein?
Possesses sialyltransferase-like activity in vitro.  Transfers sialic acid to the oligosaccharide Gal-beta-1,3-GalNAc and to glycoproteins such as asialofetuin, alpha-1-acid glycoprotein (NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-) and andasialo-alpha-1-acid glycoprotein.  The transferred sialic acid is linked to galactose of Gal-beta-1,3-GalNAc through alpha-2,6-linkage.
What are the official names of this protein?
Sialyltransferase-like protein 1, OsSTLP1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: RAKDN_HUMAN
Sequence: MLTPRKAFRTCSKESGLAETESCGQTHTWPRALAVLMGLWWPRDQKAGEEDLRFRERRPGLQATATGSGEHGAFPVHSQGVWASTHWQGTAVCPLQTPPPDAFIRNNKVLS
What are the official names of this protein?
Putative RBAK downstream neighbor protein.
Protein: TRUB_PYRHO
Sequence: MARDEVRRMLPADIKREVLIKDENAETNPKWGFPPYERPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPENKIIDVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGRDVLFKVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEKYLRRAIQPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNVGIKRGDLVAIMTLKDELVALGKAMMTSQEMMQRSKGIAVDVEKVFMPRDWYPKLW
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: FKBP5_SAIBB
Sequence: MTTDEGAKNSRGNPAATVAEQGEDVTSKKDRGVLKIVKRVGHGEETPMIGDRVYVHYNGKLANGKKFDSSHDRNEPFVFSIGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGATGSLPKIPSNATLFFEVELLDFKGEDLLEDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRCGGRVFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILHLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQIFMCQKKAKEHNERDRRTYANMFKKFAEQDAKEEANKAMSKKTSEGVTNEKLTASHAVEEEKPEGHV
What is the function of this protein?
Immunophilin protein with PPIase and co-chaperone activities.  Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) (PubMed:12538866).  Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (PubMed:11089542).  Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1.  Interacts with IKBKE and IKBKB which facilitates IKK complex assembly leading to increased IKBKE and IKBKB kinase activity, NF-kappaB activation, and IFN production (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP5, PPIase FKBP5, 51 kDa FK506-binding protein, 51 kDa FKBP, FKBP-51, FK506-binding protein 5, FKBP-5, Rotamase.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VCOM_HAEIN
Sequence: MQSIKTIRCTFCNKLLAKVGTVGYLEIKCPRCKVINFTK
What are the official names of this protein?
Mu-like prophage FluMu protein com.
What is the protein family that this protein belongs to?
Belongs to the com family.
Protein: PNP_SHEB8
Sequence: MNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKEADAGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSEDETLIARLIDRPIRPLFPNGFKNEVQVIITVVSVDPQIEPDIISMIGTSAALAISGIPFSGPLGAARVGYIDGEYVLNPSVAQLATSQLNLVVAGTAGAVLMVESEAQALPEEVMLGSVVYGHDQQQVVIKAIAEFKAEAGKPTWDWTAPTQDADLVAQIKELAEAGLGDAYKIQVKQDRYAQVSVVKAATKEALLASNPSIDLREVDNLLGSLEKKVVRGRIIRGEPRIDGREPDMIRALSVLAGVLPRTHGSALFTRGETQALVTCTLGTERDAQKIDSIMGERTNRFMLHYNFPPYSVGETGMVGSPKRREIGHGKLAWRGINAVMPSAAEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTRDGITALQMDIKIEGITKEIMDIALQQAYGARVHILNVMDQAIGSHRDDISDHAPRITVIKINPEKIRDVIGKGGAVIRALTEETGTTIELEDDGTVKIASSNGEATKEAIRRIEEITSEVEVGRIYNGKVIRIVDFGAFVNILPGKDGLVHISQISDERVANVSDHLELNQEVAVKVMEVDRQGRVRLSIKEAQTKEAAAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_RICM5
Sequence: MIKLKVKKGDEVVVITGKHKGKKGKILKVFPEDSKVIVFGVNLVKKHTKSNQMSEGGIITKELPIHISNIAHIDPKTGNPTKVAFKFLEDGSKVRVAKKSGEIIGKEGK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: TTHY_ERIEU
Sequence: MASHRLFLLCLAGLVFMSEAGPTGQSKCPLMVKVLDAVRGSPAVNVAVKVFKKAADETWEPFASGKTSESGELHGLTTDEKFVEGVYKVELDTKSYWKTLGISPFHEYVEVVFTANDSGQRRYTIAALLSPYSYSTTALVSDPKE
What is the function of this protein?
Thyroid hormone-binding protein.  Probably transports thyroxine from the bloodstream to the brain (By similarity).
What are the official names of this protein?
Transthyretin, Prealbumin.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NKX12_MOUSE
Sequence: MLAWQDVGAKAAPSHHKISFSVLDILDPQKFTRAALPPVRLAALEAKKSLEEVEAGQDACSGNPIGSQETPDAVGRGIDPGSPVEGSEAEEEEEAEDAGRAHQPERWQGVHEGSPEARAVAVGTEESGAEGLPASPGSPGSPRPRRRRAESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAVQAGGGAPQPGTPGAVAGGGGSATGSSPGPPVPGALPYQTFPTYPATNVLFPAASFPLTTAANGSPFTPFLGPSYLTPFYAPHL
What is the function of this protein?
May function in cell specification, particularly in the CNS.
What are the official names of this protein?
NK1 transcription factor-related protein 2, Homeobox protein SAX-1, NKX-1.1.
What is the protein family that this protein belongs to?
Belongs to the NK-1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAD_GEOSL
Sequence: MPTKIAVYPGSFDPITYGHLDIIDRALRIFDQVIVAVARNSAKSALFTTDERVDMIQRVLADNVRARVDTFDGLLIDYVLSQKATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMMTSVPYGYLSSSIVKEVSSLNGPIDGLVPPLVRQALRDKFAGPDR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_ECO24
Sequence: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPYR_XYLFA
Sequence: MGLELVNAGNNLPEEINVIIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVPNTLCGDGDPVDVMVVLPLPLVPGSVVRCRPVGVLQMKDEAGNDEKLLAVPVSKIFSGYSHIEDINQVSAHWLERIGHFFEHYKDLEKGKWVEIDGWGNATTAKQILTNAVQRYKDTLP
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_ANADF
Sequence: MATTIQNNFRIRRNFGKINKIAEIPNLIAIQKSSYDKFLQADVPPEKREDTGLQGVFKSVFPIKDFNETSSLEFVSYHLEKPKYDVDECHQRGMTYSAPIKVVVRLVVWDKDEETGAQSIRDVKEQEVYFGEIPLMTENGTFIINGTERVVVSQLHRSPGAFFDHDKGKSHSSGKLLFNARIIPYRGSWIDFEFDHKDILYVRIDRRRKLPATVLLRALGGVPDTAKKTPIEFHGSAEEILKYYYDTETIRIEGKGKFEKDLNPDLLKGQRATRDIRDPKTNEIVVKKNRKFTESAIKKLVAAKMKSLPIEPEEVYTKISAEDVVDEQTGEVLLEVNEEVSEEKLEELRKRGIGEFKVLFIDNLNVLPSLRDTLMQDKISTPEEAIMEIYRRLRPGDPPTPETATNLFVNLFFNAERYDLSKVGRLKLNYKFGIEEPLDNTVVTKRDILEVVRFLIDLKNGTPNKDVDDIDHLGNRRVRAVGELLENQYRIGLVRMERAIKERMSLQEIETLMPHDLINAKPVTAVIKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHSTHYGRICPIETPEGPNIGLIASLSTYARVNEYGFVETPYRKVEKGRVTDEVSFYSALEEEKHIIAQANAPVDKKGVFTGNIVSCRKEGEYINARPDEVDLMDVSPNQLVSVAASLVPFLENDDANRALMGSNMQRQAVPLLRTRAPLVGTGIEGIVARDSGVCVVAKRDGVIQSVDAARIVVKADVPTSATDVANEVDIYNLIKYQRSNQNTCINQKPIVKPGERVKKGDVIADGPATEMGELALGQNVVVAFMPWQGYNFEDSILLSERFLKDDVFTSVHIEEFECVARDTKLGKEEITRDIPNVGEEALKDLDESGIIRIGAEVKPGDILVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDSSLRVPPGVSGTVINAKVFSRKGVEKDERAKAIEEMEEAKLLKDQNDEIRIIQDSAFQKIRRLLLGKEVSGRLVDDKGNQLLKRGDVLDDALLDTVPQRYWGEIAVEGDVQDLVRKIVENFEEQKELVKLLFGEKIGRLKKGDELPPGVIKMVKVYVAIKRKLAVGDKMAGRHGNKGVVSRVLPEEDLPYLEDGRPVDIVLNPLGVPSRMNVGQILETHLGWAAKNVGWRLQEMIEKNFGPDQLRKKLKKAFEGVEGSDRLGQLIDELPAQELPKLATKLKEGMHVATPVFDGAHEDEMKALLGEGSATMQSILFDGRTGEPFDQDVTVGVMYMLKLHHLVDEKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYSLQEFLTVKSDDVVGRTRMYEAIVKGENTLESGLPESFNVLIKELQSLALDVELLETPEAKAAREQAEGELGGPLGTPRGAAAEKNTA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: KLK1_BLABR
Sequence: YLLLLCLPLTLMGTGAVPPGPSIEIHPRIVGGWECDKHSQPWQALLTFTNGLDGVCGGVLVHPQWVLTAAHCIGDNYKIKLGLHDRFSKDDPFQEFQVSASFPHPSYNMRLLKLLLSDELNDTYYDEISLGADFSHDLMMMQLEKPVQLNDAVQVLDLPTQEPQVGSKCHASGWGSMDPYSRNFPRTGKLQCVDLTLMSNNECSRSHIFKITDDMLCAGHIKGRKDTCGGDSGGPLICDGVFQGTTSWGSYPCGKPRTPGVYVKIFSHVDWIREIIATHS
What is the function of this protein?
A kallikrein-like protease.  It preferentially converts human high-molecular-weight kininogen (HK) to bradykinin.  Displays broad substrate specificity in vitro, with highest activity toward Boc-Val-Leu-Lys-MCA, Boc-Glu-Lys-Lys-MCA, Boc-Glu(OBzl)-Ala-Arg-MCA, Boc-Val-Pro-Arg-MCA, ZPhe-Arg-MCA and Pro-Phe-Arg-MCA.  Has preference for Arg and Lys in position P1 and hydrophobic residues in position P2.  Is not toxic to mice.
What are the official names of this protein?
Blarinasin-1, Kallikrein-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.