PharMolix/UniProtQA huggingface dataset:
Protein: SYT_AROAE
Sequence: MPNITLPDGSVRSFDHPVTVSEVASSIGAGLAKAALAGKVDGRLVDLSYRIEADTPLAIVTEKGDEGLDVIRHSTAHLLAHAVKELFPEAQVTIGPVIENGFYYDFAYKRPFTPEDLEKIEKRMAELARREIPVSREVWPRDKAVEFFKSQGEHYKAEIIASIPQAEDVSLYRQGDFIDLCRGPHVPSTGKLKVFKLTKVAGAYWRGDSKNEMLQRIYGTAWAKKDDLENYLHMLEEAEKRDHRKLGRLLDLFHIQEEAPGMVFWHAKGWTLWQQVEQYMRRTILDNGYQEVKTPQIVDRSLWEKSGHWDMYSELMFTTQSEKRDYAVKPMNCPCHIQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGIMRVRNFVQDDAHIFCADEQVQTEAAAFIELLQKVYADFGFTEILIKLSTRPDKRVGTDDQWDAAEAALAAALDAQGLAYDLQPGEGAFYGPKIEFSLKDCLNRVWQCGTLQLDFNLPVRLGAEYVAEDNAKHYPVMLHRAILGSLERFIGILIEHYAGALPLWLAPVHAVVLNISEGQTDYATEVARRLKQAGFRVEADLRNEKINYKIREHSVHKLPYQIVIGEKEKAAGVVAVRARGGQDLGQMPLDTLIERWQREIEARSGSI
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACON_GRAGA
Sequence: MIAMDRIARIPIARWTSRAFRVSAAARQTPMSPLEAHNELEPVYAAIDDRLNTVRSKLNRPLTLAEKVLYGHLDDPERVPVRGETFLKLRPERVALQDATAQMALIQFMASARPQVAVPSTIHCDHLIAAEVGAEEDMAKAKSQNKEVYDFLASAGAKYGLGFWKPGSGIIHQIVLENYAFPGLLMIGTDSHTPNAGGLGACAVGVGGADAVDVMVGLPWELKAPKVIGVKLTGKLQEWASPKDVILKVAGILTVKGGTGAIVEYFGEGVDSLSCTGMGTICNMGAEIGATTSMFPYNSRMGDYLKATGRDGIASLADSFSEQLRADENAVYDQLIEINLSELEPHINGPFTPDLAHPLSKFKEEVEKNGWPAELTVGLIGSCTNSSYEDMARSASVVKQALSHGVKSKSIFNITPGSEQVRATISRDGILDTFTEAGGTVLANACGPCIGQWNRSDVPKGTPNSIITSFNRNFSQRNDGNPQTHAFVASPEIVTAMSLAGSLKFNPATDSLQGADGAEFKLAAPSGDELPVMGFDPGEDTFQPPSDDSTSILVQIDPDSQRLSFLEPFPAWDGKDYTDMPVLIKARGKCTTDHISMAGPWLKFRGHLDNISNNMLIGAVNDENGEINNVKNAVTGEYGTVPDTARAYKAEGVKWVVIGDENYGEGSSREHAALEPRHLGGVAVIVKSFARIHETNLKKQGMLPLTFNNPADYDKIDSSDKVSLVGLKNLTPGEPVTMTVTKADGTSMDILLNHTFNDEQLEWFRAGSALNKIKIDLGT
What is the function of this protein?
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
What are the official names of this protein?
Aconitate hydratase, mitochondrial, Aconitase, Citrate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MCIN_MOUSE
Sequence: MQACEGSAAGRRAFDSICPNRMLDLSRRTLGKPGKPERKFVPSWKSFSGCGGGSPVAVYEDPPDAEPAPLPALTTIDLQDLADCTSLLGTEASPSGDSSASQNPSLQTEEDFNLQNFRDAMDDLIADSSSLMSPPLTNSDFPFSPCDVSSFGSCLSPSLDPPALGSPDLPPPPTEQYWKEVADQNQRALGTALIENNQLHVTLTQKQEEIASLRERNVQLKELASRTRHLASVLDKLMITQSPAEPFQIKATTKRSLEELFCAAGQAGQGCAEVDAILRDISQRCEEALHNRDPKRPRLQPEPDSKDCSSRNLHGAFRGLRTDCSASSVNLSHSELEEGGSFSTPIRSHSTIRTLAFPQGKAFTIRTVTGGYKFRWVPS
What is the function of this protein?
Transcription regulator specifically required for multiciliate cell differentiation.  Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis.  Required for the deuterosome-mediated acentriolar pathway.  Plays a role in mitotic cell cycle progression by promoting cell cycle exit.  Modulates GMNN activity by reducing its affinity for CDT1.
What are the official names of this protein?
Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, McIdas protein, Protein Idas.
What is the protein family that this protein belongs to?
Belongs to the geminin family.
What are the subcellular locations of this protein?
Nucleus. Note=Excluded from the nucleolus.
Protein: G3P_NEUCR
Sequence: MVVKVGINGFGRIGRIVFRNAIEHDDIHIVAVNDPFIEPKYAAYMLRYDTTHGNFKGTIEVDGADLVVNGKKVKFYTERDPAAIPWSETGADYIVESTGVFTTTEKASAHLKGGAKKVIISAPSADAPMYVMGVNNETYDGSADVISNASCTTNCLAPLAKVIHDNFTIVEGLMTTVHSYTATQKTVDGPSAKDWRGGRTAAQNIIPSSTGAAKAVGKVIPDLNGKLTGMAMRVPTANVSVVDLTARIEKGATYDEIKEVIKKASEGPLAGILAYTEDEVVSSDMNGNPASSIFDAKAGISLNKNFVKLVSWYDNEWGYSRRVLDLISYISKVDAKKA
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Clock-controlled protein 7.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_ECOLI
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIAHELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.  It can use ATP and other nucleoside triphosphates (UTP, CTP, GTP, dATP, TTP) as phosphoryl donors, while nucleoside mono- or diphosphates and poly(P) cannot.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPHB_PYRHO
Sequence: MVLYFIGLGLYDERDITVKGLEIAKKCDYVFAEFYTSLMAGTTLGRIQKLIGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYDVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRVNV
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: CBPQ_XENLA
Sequence: MKTLILTLLSLYELQLCCGAYNQNIRSQRKFEMIKTEISSYKDVAKSIIDLAVHGKAQNRSYERLALFVDTVGNRMSGSENLKTAIAYMYKSLQEDDLDRVYLEPVKVPHWERGEESAMLLEPRKKSLAILGLGGSIGTPVEGISAEVIVVSSFAELHNRSKEAKGKIVVYNEPFVNYGETVRYRGSGAVEAAKVGAVASLIRSVTPLSVYSPHTGWQWYENDVPKIPTASITVEDAEMLSRMASRGLKIVIQLKMGAVNHPDADSYNTVAEIVGSKYPEQVVIVSGHLDSWDVGQGAMDDGGGAFISWEALSLIKDLGLRPKRTLRLVLWTGEEQGGVGASQYYELHKKNISNIDLVMESDIGTFMPLGMQFTGKPEARAIMTEVMQLLQPINITSLYDYAEGTDINSWMQAGVPGASLFDDISKYFWFHHSQGDTMTVQDPVWMNLCAAVWTVVSYVVADMEEMLPR
What is the function of this protein?
Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides.  Catalyzes more efficiently the hydrolysis of dipeptides with unsubstituted terminals into amino acids (By similarity).
What are the official names of this protein?
Carboxypeptidase Q, Plasma glutamate carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Lysosome. Secreted.
Protein: CSPA_STAAN
Sequence: MKQGTVKWFNAEKGFGFIEVEGENDVFVHFSAINQDGYKSLEEGQAVEFEVVEGDRGPQAANVVKL
What is the function of this protein?
Involved in cold stress response.
What are the official names of this protein?
Cold shock protein CspA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_NOSP7
Sequence: MQPRKPQQIARELALLSLSQLPVNPKKLDTLLDDQLVSKLVLGAVRTLTSEVQDTLNNAAGELQRSNDRLLSSQTRASDLNSARTMLQEAIACTQTAINQLGTAVDFPELIQLANQDKGVRNYAKELVITVNENRHIIDELLSTALVDWQVTRLAQLDRDILQIAVAEMKFLGVPDSIAINEAVELAKRYSGDDGHRFINGVLRRVTEQKKTA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: HDA_ECOL5
Sequence: MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: SCD_CAPHI
Sequence: MPAHLLQEEISSSYTTTTTITAPPSKVLQNGGGKLEKTPLYLEEDIRPEMRDDIYDPTYQDKEGPKPKLEYVWRNIILMGLLHLGALYGITLIPTCKIYTFLWVLFYYMMSALGITAGVHRLWSHRTYKARLPLRVFLIIANTMAFQNDVFEWSRDHRAHHKFSETDADPHNSRRGFFFSHVGWLLVRKHPAVREKGATLDLSDLRAEKLVMFQRRYYKPGVLLLCFILPTLVPWYLWGETFQNSLFFATLLRYAVVLNATWLVNSAAHMYGYRPYDKTINPRENILVSLGAVGEGFHNYHHTFPYDYSASEYRWHINFTTFFIDCMAAIGLAYDRKKVSKAAALARMKRTGEESCKSG
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity).  Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids.  Plays an important role in lipid biosynthesis.  Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity).  Plays an important role in body energy homeostasis (By similarity).  Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).
What are the official names of this protein?
Stearoyl-CoA desaturase, Acyl-CoA desaturase, Delta(9)-desaturase, Delta-9 desaturase, Fatty acid desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: END4_STAES
Sequence: MLIGSHVSMSGKKMLQGSAEEAHKYGESTFMIYTGAPQNTRRKNIEDLNIEKGQQAMKTYGLSNIVVHAPYIINIANTTKPEVFNLGVDFLQKEIERTQALGAKDIVLHPGAHVGAGVDKGIQKIIEGLNEVLTHDNDVRIALETMAGKGTEVGRSFEEIAQIIDGVTHNDRLSVCFDTCHTHDAGYNVKEDFDGVLEKFDSIIGVDRIKVVHVNDSKNLRGAQKDRHENIGFGHIGFDALNYVVHHDTFKNIPKILETPYVGEDKKNKKPPYKLEIDMLKSQKFDPELKNKILTQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: SYK_BACCR
Sequence: MDNMNHEELNDQLIVRREKLHNLREQGIDPFGKRFERTNSTTDLVSLYGEFSKEELEEKEIAVSIAGRIMTKRGKGKAGFAHVQDLHGQVQIYVRKDAVGDDEYELFKTADLGDLVGIEGKVFKTNVGELSVKATGFTLLTKSLRPLPDKYHGLKDVEQRYRQRYLDLITSMESRETFVTRSKIIREMRRYLDDNGYLEVETPMMHAIAGGASARPFTTHHNALDMELYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMKLTEDMVAHIAKKVLGTTTIQYGDYEINLEPEWTRLHMVDAIKQYSGADFWNPMSVEEARELAKEHNVEIKDTMEVGHIINEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNDEDPRFTDRFELFIVAREHANAFTELNDPIDQKERFEAQLKEREQGNDEAHMMDDDYIEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPAMRHKQD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCES_PICST
Sequence: MSSNTDAEIQLLQSIKEKAAAAGTQNSAASTSGSSSDSKITRESSAFSRREITNDVPIVSSAYSEVKEAPAWVKKDTPVDKYDKYGSRPAVSTSSGPSRVSRPESESTDNKYSKYISRAAEPSTRVKRSREEFEREEPDPREYGNSRIEQEKDDDGGAAIPYSNLDVSNQSYDHRTLQSREYYTFQSHISNKEERDINSIVRTHYNQRAVHSKRQVRKNSPIIKMRNFNNAIKYMLLGNYSKREQGVDRPFTFLDLCCGKGGDLNKCQFLEIDQYIGIDISDVSVKEAFQRYSQKKVRFRSAYGQKPRKDELRYDFEACFATGDCFSKTIPELLEPNFPGIIDKTFPVDTVSIQFSLHYAFETEDKVRTILTNVSRSLRPGGKFIGTIPSSDFIRKKIVTKNYLPDDRGKKKFGNSLYSVTFDKEPPEDGVFRPPFGNKYNYSLKDAIDDVPEYVVPFETLRAMCEDVGMELKLKKNFIDIFNQEIPKYFSKLSKHLIEGMKRSDGKYGAEGEEKEAVGFYIGFVFEKLGS
What is the function of this protein?
Responsible for methylating the 5'-cap structure of mRNAs.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMO_KINRD
Sequence: MPPTSGTSRSVALVTLGCARNDVDSEELAGRLADAGWTLVDDADGADVAVVNTCGFVEQAKKDSIDTVLAAADLKEAGRTKAVVAVGCMAERYGKDLAESLPEADAILGFDSYGDLSSHLEAILHGEKPQSHVPRDRRTLLPLAPAERQAARPVIAEPDLPEGLAPASGPRVVRRRLGSGPWAPVKIAAGCDRRCTFCAIPAFRGSFVSRPAEEVLAETRWLAEQGVKEVFLVSENTTSYGKDLGDLRALEALLPHVAAVEGIERVRVSYLQPAEVRPGLLDALTSTPGVVPYFDLSFQHSSPAVLRRMRRFGGTEPFLALLEQVRERHPQAGIRSNVIVGFPGETEADVDELCSFLERARLDVVGVFGYSDEDGTEAETLDGKLPDEVVAARVDRVTRLVEELVTQRAEERLGEVVEVLVESVVDEDGDPHVVGRAAHQGPDVDGETELDLPAGFVVHVGDLVTARVTGVAGADLLAEPLVRATV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CENPQ_MOUSE
Sequence: MSGKARASRKKPQQVKRSLKQRANKEADLPENEVGNTAKRNRSHAKHLSSKVTGQATYVHLKRVKISSSKRTTWQPLPKDTEEYLQSMMESVILGILFNIKRKEEIQCHLNQLKKRLLQQCATLKVPPRKLNYLKDVSKMLKMEKAQERANEESLASLQEEIDKIVETTESMTESIQSLKNKIQILTSEVEEEEQEVKQVFHIDSNKVLALPELSQKSLKAPILQEEILALIPNQNALLKDLDVLHDSAPVKNVSAFIEEAYKKLDS
What is the function of this protein?
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.  Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores.
What are the official names of this protein?
Centromere protein Q, CENP-Q.
What is the protein family that this protein belongs to?
Belongs to the CENP-Q/OKP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Protein: DDRGK_DROYA
Sequence: MELIILVGIATALLVVIITLYLLQKKNAAPETKPAAALQRGVPQRVQEGVPRRAQIARNQRNRLRQNAPAAPAGQVAPAAGPPAAPGDSDHENEGQVDDDDARVPQGAVLDEKMGAKKRAKMEAKEQKRLQREQELHDREQRKVKEAKEEAERKHQEDLEAEVERKRVEAERLAKEERERKEHEEYLKMKAAFSVEEEGFEEGDADEQDSLLADFIQYIRDNKVVVLEDLAVAFKLKTQQVIDRIQELQADGTLTGVIDDRGKFIYVSEEELSAVAKFIKQRGRVSIAELAESSNNLINLTPISAGGEEASS
What is the function of this protein?
Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins.
What are the official names of this protein?
DDRGK domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
Protein: RL27_TROWT
Sequence: MAHKKGASSSRNGRDSNAKRLGVKRFAGQVVSAGEILVRQRGTRFHPGTNVRRGDDDTLFALASGRVRFGRSGKRRAVSVDT
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: KYNU_GEOTN
Sequence: MNSTALEPTLEFARKLDQEDPLRHFRDEFYLPPNSIYMDGNSLGLLSKRAEKTLFTILQDWKLLGIDGWTKGTYPWFDLSEKIGAMLAPLVGASPEEVIATGSTTVNLHQLVSTFYQPEGKRTKILADELTFPSDIYALQSQLRIHGYDPSTHLIRVKSRDGRFLEEEDIIAAMSEDVALVVLPTVLYRSGQILDIQLLTDEAHKRGILIGFDACHSIGAIPHSFSEWGVDFAFWCNYKYMNGGPGCVAGLYVHRKHFGSAPGLAGWFGSKKDKQFDMEHTFTPSLTAGAYQIGTPHLLSLAPLIGSLEIFQEAGIERIRQKSLQLTNYFMYLIEQELSHFGFIIGNPKDDVRRGGHISLEHEEAARICKSLKENGVIPDFRAPNIIRLAPIALYTSYEEVWNVVQIMKKIMQEKQYKKFSNEREVVA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: RL28_DESPS
Sequence: MAKVCEICGKGPITGNNVSHAHNKTRRRWLPNLKKVRMVTASGATVRGKVCTRCIRSGAVVKPA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: LR75B_HUMAN
Sequence: MGARLGRRAGPEAGSEAGAAAGCGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLERTLLPDILYRDVAFLNPVDPISHDLLVNLARDLQCPKKDYELWKSSDKICRQLIYHLTPHSKQQQGSSLRQRKTQSCLKSSLQKTLLAGETVDLSGIPLSTQDVQHITRYLSSHGAVLAVLDLSFTGLSDELLHLLLPSLWALPRLTQLLLNGNRLTRATARKLTDAIKDTTKFPALAWVDLGNNVDVASLPQPLLVGLRRRLSQRTSLPTIYEGLDLEPEGSAAGATTPASTWDSTAAGLGPEPQACCAR
What is the function of this protein?
May suppress myogenic differentiation by modulating MYOG expression and Erk1/2 signaling.
What are the official names of this protein?
Leucine-rich repeat-containing protein 75B, Leucine-rich repeat-containing protein FAM211B.
What is the protein family that this protein belongs to?
Belongs to the LRRC75 family.
Protein: COAD_SALG2
Sequence: MQKRAIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPGKKPMFTLDERVALAQKATAHLGNVEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQLAHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPDNVHQALMDKLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_STRTD
Sequence: MSTTIIGFPRLGEFRELKFTTEKYFRNEITADELLAAAKDLRAKHWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPESVKNLDLTELEQYFALARGYQGEKGDVRALPMKKWFNTNYHYIVPKFEKTTAVKLAGHKIFDEYQEAKDLGLDTRPVVVGPFTFLQLSDFEDGVKAEDFVDSFIAAYQDVFAKLAELGATRIQLDEPALVKDLTADEKALFLNLYNKILADKKGLEVLIQTYFGDVRDVYNDLVNLPVDAIGLDFVEGKKTLELVKGGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAEKIVLTSSCSLLHVPFTTANEEFEPAILNHFAFAVEKLDELRDLDAIRNGQGAESLAANKELFAIERVGANAELRARIAGLTEADYTRLPAFAEREAIQKDAFKLPLLPTTTIGSFPQTKEVRAKRLAFRKNELSQEEYDAFLAEIIDEWIKWQEEVGFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGMRGVKPPIIWGDVTRLNPITVKWSSYAQSRTDKPVKGMLTGPVTILNWSFPREDISIKDSTLQIALAIKDEVLDLEAAGIKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVHSTVAPDTQIHTHMCYSEFTDIIPAIDNLDADVISFEASRSNLEILDELKAQNFQTEVGPGVYDIHSPRVPQDGEIDHTIEAILAKVPSSKVWINPDCGLKTRGIKETKESLTKLLEAAKAARKNL
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RL25_ECOBW
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: RRF_METPB
Sequence: MATPEFDLGDIKRRMQGAVSSLSKDLGSLRTGRATPSLLDPIQVEAYGASMPMAQVATVSVPEPRLLSISVWDRSMVTNVEKAIRESDLGLNPMTEGQTIRLRIPEMNEQRRKEMVKVAHKYTEEARVAVRHVRRDGLDILKKLEKDGAISEDDEKRQAGEVQKATDDAIAEIDGVLASKEKEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_GLAP5
Sequence: MSQLTTVARPYAKAAFDFALEQGQLDKWQEMLQFSALVAENEDVQHFIHSSSAATQVADTFIAICGDQLDQYGQNFIRVMAENKRLSALPSVFASFNQIRAEYESVKDVFVTSATPLTKAQEDKIAKAMKQKLNSEVRITTSIDASLIAGVIIRYDDVVIDGSSRGQLNRLSQELCL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KIRR1_HUMAN
Sequence: MLSLLVWILTLSDTFSQGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGERVVFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQYAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPVGIIAGATIGASILLIFFFIALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTASVSTATRVMKAIYSSFKDDVDLKQDLRCDTIDTREEYEMKDPTNGYYNVRAHEDRPSSRAVLYADYRAPGPARFDGRPSSRLSHSSGYAQLNTYSRGPASDYGPEPTPPGPAAPAGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTPYEAYDPIGKYATATRFSYTSQHSDYGQRFQQRMQTHV
What is the function of this protein?
Required for proper function of the glomerular filtration barrier.  It is involved in the maintenance of a stable podocyte architecture with interdigitating foot processes connected by specialized cell-cell junctions, known as the slit diaphragm (PubMed:31472902).  It is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity).
What are the official names of this protein?
Kin of IRRE-like protein 1, Kin of irregular chiasm-like protein 1, Nephrin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Predominantly located at podocyte slit diaphragm.
Protein: YVN1_AZOVI
Sequence: MSKSVINTDKAPAAIGTYSQAIRAGDTVYLSGQIPLDPGTMELVEGDFEAQTVRVFENLKAVVEAAGGSFADIVKLNIFLTDLAHFANGNECMGRYFAQPYPARAAIACASLPRGAQVEMDGILVLG
What are the official names of this protein?
RutC family protein in vnfA 5'region, ORF1.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: 3MGH_MYCTO
Sequence: MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRNDVMFGPPGRLYTYRSHGIHVCANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAVALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHRARSGPRVGVSQAADRPWRLWLTGRPEVSAYRRSSRAPARGASD
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.