PharMolix/UniProtQA huggingface dataset:
Protein: TRAP_STAAS
Sequence: MKKLYTSYGTYGFLHQIKINNPTHQLFQFSASDTSVIFEETDGETVLKSPTKYDVIKEIGEFSEHHFYCAIFIPSTEDHAYQLEKKLISVDDNFRNFGGFKSYRLLRPAKGTTYKIYFGFADRHAYEDFKQSDAFNDHFSKDALSHYFGSSGQHSSYFERYLYPIKE
What is the function of this protein?
Signal transduction protein, which is a major regulator of staphylococcal pathogenesis.  Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors.  Up-regulates the expression of most toxins and genes known to be necessary for biofilm formation (By similarity).
What are the official names of this protein?
Signal transduction protein TRAP, Target of RNAIII-activating protein.
What is the protein family that this protein belongs to?
Belongs to the TRAP family.
What are the subcellular locations of this protein?
Membrane. Note=Membrane-associated.
Protein: RNH2_MARMS
Sequence: MEPFVSRIYFGDLLAGTDEAGRGPLAGEVVAAAVILDPAQPITGLADSKKLSEKKREALFVEIQEKALAYGIARATIEEIDELNILHASMLAMSRAVALLSIEPEYVLVDGNRIPPNLPCSAEAVVKGDARHAAISAASILAKVTRDRDIVQVAQIYPEYGFEKHKGYPTALHLEAIRLHGITPIHRRSFGPVKKILEG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_THESQ
Sequence: MRPEDDRVYDVIVVGAGHAGIEAALAAARMGFRVLVLTVNPDTVGWAPCNPAIGGPAKGVVVREIDALGGEMAKTTDETMINVRMLNVSKGPAVRALRAQIDKISYSRTMKRKLETNPNIVLRHGIVERILTEKGRVKGVVDNYGIDYLGKAVIVTTGTFLRGKIFIGRSTFPAGRMGEFPATKLTESLIELGFEVGRFKTGTPARVLKRSINFSVMERQDTSDEPLAFSFFDEPRVLPKDYPCWLTRTNPETHSIIKQYLEFSPLYGTVKLIEGIGPRYCPSIEDKVVKFKDKESHQVFVEPEGRDTEEYYLNGLSTSLPYEAQIKMIRSVKGLENAIVTRPAYAIEYDYIDPRQLYPTLESKLVENLYFAGQVNGTSGYEEAAGQGIIAGINAALKLRGEPPLILKRSEAYIGVLIDDLVTKGVDEPYRLLTSRAEYRLLLRHDNAHLRLAKYGYRVGLIPKWFYEKVLSLERRINEEIERLKKVIVKPSDRVNDLLTSLGTSPLKESVSLYQLLKRPQLSYSALKFLDPNPIDDPEVVEQVEINVKYEGYIQKMFEEVAVFEKYENYEIPHDLDYDAVPNLSTEARDKLKKIRPRSIGQAMRIPGINPSDISNLIIYLDRKKQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBSP1_ANOGA
Sequence: MEEDLMEYAPNIPDNVLELIFSFLKLQDLRNCTLVCKSWYRFFCDENNEVWRAQCLQKVPAEAFKNDLLTVVPTYKAKLRAYFHAWNPFDCSRHVYIKPNGFTLHRNPVAQSTDGSRGKIGFKHGRHAWEVRWEGPLGTVAVVGIATKDAAIQCHGYYALLGADDQSWGWNLVDNLLLHNGDAHGIYPLLNNAPKYKVGERIRVILDCDENTLSFEKNYEFLGVAFTDLPEKNFYPTVAAVYGNTEISMVYLGAPLDG
What is the function of this protein?
Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ).
What are the official names of this protein?
F-box/SPRY domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the FBXO45/Fsn family.
What are the subcellular locations of this protein?
Synapse.
Protein: END3_MAGO7
Sequence: MAPRIEAQEIETYWNIFSARTNGSKFLTGEQAAPVLKNSGLRDDQLERVWDLADVDNDGNLDFEEFCVAMRVIFDILNGEHADVPSTLPDWLVPESKAHLVQANRALTGKQVQFERVDDDPDSPGLKDGFDWYMSPADKSKYESIYQENRDMRGEVSFGALEDLYESLDVPDTDIRSAWNLINPSAGPTINKDACLAFLHILNYRHEGYRIPRTVPASLRASFERNKIDYQVDKQAASRWATKADDETSTGRKAKFGDQYLTRLGRGSFKTSGTDFSSAQTDSEWEEVRLKKQLAELDAKMASVEADAERRKGGKRDSKPALVKRELEQLLDYKRKQLREIEEGKTKGQGGGSLKGIQDDLQTVREQTDGLASHLRSRQQHLEELRRQIEDEKAGR
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein END3, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: N6MT1_HUMAN
Sequence: MAGENFATPFHGHVGRGAFSDVYEPAEDTFLLLDALEAAAAELAGVEICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACTLETARCNKVHIQPVITDLVKGLLPRLTEKVDLLVFNPPYVVTPPQEVGSHGIEAAWAGGRNGREVMDRFFPLVPDLLSPRGLFYLVTIKENNPEEILKIMKTKGLQGTTALSRQAGQETLSVLKFTKS
What is the function of this protein?
Methyltransferase that can methylate proteins and, to a lower extent, arsenic (PubMed:18539146, PubMed:21193388, PubMed:30017583, PubMed:31636962, PubMed:31061526).  Catalytic subunit of a heterodimer with TRMT112, which monomethylates 'Lys-12' of histone H4 (H4K12me1), a modification present at the promoters of numerous genes encoding cell cycle regulators (PubMed:31061526).  Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5-methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif (PubMed:18539146, PubMed:31632689, PubMed:31636962).  Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated (PubMed:18539146, PubMed:20606008, PubMed:31636962, PubMed:31061526).  May also play a role in the modulation of arsenic-induced toxicity by mediating the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid (PubMed:21193388, PubMed:25997655).  It however only plays a limited role in arsenic metabolism compared with AS3MT (PubMed:25997655).
What are the official names of this protein?
Methyltransferase N6AMT1, HemK methyltransferase family member 2, M.HsaHemK2P, Lysine N-methyltransferase 9, Methylarsonite methyltransferase N6AMT1, Protein N(5)-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal PrmC-related family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FER_ACIAM
Sequence: GIDPNYRTSRQVVGEHQGHKVYGPVDPPKVLGIHGTIVGVDFDLCIADGSCITACPVNVFQWYDTPGHPASEKKADPINEQACIFCMACVNVCPVAAIDVKPP
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.  The 3Fe-4S cluster is reduced by a flavoprotein with NADH oxidase activity from the same organism.
What are the official names of this protein?
Zinc-containing ferredoxin, Seven-iron ferredoxin.
Protein: KI10A_DROME
Sequence: MDMITVGQSVKIKRTDGRVHMAVVAVINQSGKCITVEWYERGETKGKEVELDAILTLNPELMQDTVEQHAAPEPKKQATAPMNLSRNPTQSAIGGNLTSRMTMAGNMLNKIQESQSIPNPIVSSNSVNTNSNSNTTAGGGGGTTTSTTTGLQRPRYSQAATGQQQTRIASAVPNNTLPNPSAAASAGPAAQGVATAATTQGAGGASTRRSHALKEVERLKENREKRRARQAEMKEEKVALMNQDPGNPNWETAQMIREYQSTLEFVPLLDGQAVDDHQITVCVRKRPISRKEVNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLENHKFRFDYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKNGIYAMAAKDVFVTLNMPRYRAMNLVVSASFFEIYSGKVFDLLSDKQKLRVLEDGKQQVQVVGLTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRPQGSTKIHGKFSFIDLAGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALGKQSAHLPFRVSKLTQVLRDSFIGEKSKTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVEVCPGGDTEPIEITDDEEEEELNMVHPHSHQLHPNSHAPASQSNNQRAPASHHSGAVIHNNNNNNNKNGNAGNMDLAMLSSLSEHEMSDELIVQHQAIDDLQQTEEMVVEYHRTVNATLETFLAESKALYNLTNYVDYDQDSYCKRGESMFSQLLDIAIQCRDMMAEYRAKLAKEEMLSCSFNSPNGKR
What is the function of this protein?
Required during anaphase to drive sister chromatid separation to promote flux by actively depolymerizing kinetochore microtubules at their pole-associated minus ends, thereby moving chromatids through a 'poleward flux' (PubMed:14681690, PubMed:20946984, PubMed:24100293).  Involved in asymmetric cell division of sensory organ precursor (SOP) cells by playing a role in the asymmetric localization of Sara-expressing endosomes to the pIIa daughter cell but not to the pIIb cell.  Klp98A targets Sara-expressing endosomes to the central spindle which is symmetrically arranged in early cell division.  During late cytokinesis, central spindle asymmetry is generated by enrichment of Patronin on the pIIb side which protects microtubules from depolymerization by Klp10A while unprotected microtubules on the pIIa side are disassembled by Klp10A, leading to the asymmetric delivery of Sara-expressing endosomes to the pIIa daughter cell (PubMed:26659188).
What are the official names of this protein?
Kinesin-like protein Klp10A, Kinesin-like protein at cytological position 10A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Chromosome, centromere. Note=Localizes to mitotic centrosomes, spindle poles and centromeres through metaphase (PubMed:14681690). However, the centromeric localization diminishes markedly at the onset of anaphase, leaving the majority of the protein on the spindle poles (PubMed:14681690). Concentrated around the minus ends focused at the poles (PubMed:14681690, PubMed:24100293).
Protein: OR4D1_HUMAN
Sequence: MEPQNTTQVSMFVLLGFSQTQELQKFLFLLFLLVYVTTIVGNLLIMVTVTFDCRLHTPMYFLLRNLALIDLCYSTVTSPKMLVDFLHETKTISYQGCMAQIFFFHLLGGGTVFFLSVMAYDRYIAISQPLRYVTIMNTQLCVGLVVAAWVGGFVHSIVQLALILPLPFCGPNILDNFYCDVPQVLRLACTDTSLLEFLMISNSGLLVIIWFLLLLISYTVILVMLRSHSGKARRKAASTCTTHIIVVSMIFIPCIYIYTWPFTPFLMDKAVSISYTVMTPMLNPMIYTLRNQDMKAAMRRLGKCLVICRE
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4D1, Olfactory receptor 4D3, Olfactory receptor TPCR16.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS16_CHLPB
Sequence: MVKIRLRRAGRKKLPVYQIVAADARAPRDGKFLEVIGHYQPTAKPHAITLDKERVAYWLGVGAQPTTTAHSLIRATGLLHEMNMKRKGRSEEEIAAEMEQWQARQNERREKRLAIKTRRRQAKKAAEAEGQESA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL25_HISS2
Sequence: MSFKFNAEVRSKQGKGASRRLRHNGQIPAIVYGGSEAPVSIVLNHDELNNAQIHDSFYSDTIILVIEGKEISVKVQAMQRHPFKPKLVHIDFKRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: ORN_LEGPH
Sequence: MKNNQNLIWIDLEMTGLEPEQDRIIEMATIVTDPQLNILAEGPVIAVSQPKILLDSMDAWNTKQHNQSGLVKRVLESNVSESQAEQLTIEFLKQYVDKGKSPMCGNSICQDRRFLYKYMPELAAYFHYRNLDVSSLKELVLRWRPELMNGVVKESKHLALDDIKDSINELIYYRQHFINLPEVKNDK
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_PHOV8
Sequence: MSENIKPSEVSEVLLQQLKGIDTHLQFDEVGNVLQVSDGVARIYGLRNAEANELLEFENGIMAIVMNLEEDNVGAVLLGPTDQIKEGMVVKRTKRIASINVGEGMLGRVIDPLGVPLDGRGQIGGELCEMPLERKAPGVIFRQPVNQPLQTGLKSVDAMIPIGRGQRELIIGDRQTGKTSIAIDTILNQKSNYEAGKPVYCIYVAIGQKGSTVASLVNTLRERGAMDYTIVVAATAADPAALQYFAPFAGAAIGEYFRDTGRDALVVYDDLSKQAVAYREVSLILRRPSGREAYPGDIFYLHSRLLERAAKIINQQEVAEQMNDLPPSLKGKVKAGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNQGFRPAINVGISVSRVGGSAQIKSMKKVAGTLKIDQAQYRELEAFSKFSSDMDPVTAMAIDRGRKNNQLLIQPQYSPMPVGEQIAILYCGTHSLLRDVPLHKVQDFQKSFLEMMRADHQKDVLDVLSSGVINDDVTAIIEKVAADTAQPFKVNE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYT_DESRM
Sequence: MIKITLKDGSVREYAVGTTVLEVAKSISQGLAREALAGKVNGKIVDLEYPLKEDAALELLTFNDEEGKTVYRHSTAHVLAQAVKRLFPDAKLAIGPAIQDGYYYDFDVEQPFTPAQLERIEEEMNKIIKEDIPFKRVELSREEALEHFKKQDEIYKIELITDLPEDAVISCYQQGDFDDLCAGPHVPSTGRLKSLKLMSIAGAYWRGSEKNKMLQRIYGTSFPKKAMLDEHLFRIEEAKRRDHRKLGQELDLFSIQEEGPGFPFFHPKGMVLRNELENFWRQEHKKRGYQEIRTPIILNRSMWEQSGHWAHYKDNMYFTKIDEADYAVKPMNCPGSILVYKTRMHSYRDLPLRWGELGLVHRHELSGALHGLMRVRCFTQDDAHIFMLPSQIKDEIIGVIDLFDYFYNTFGLNYHVELSTRPEKSMGSDEMWEVATNSLRDALEAKKMDYKVNEGDGAFYGPKIDFHLTDSLGRTWQCGTIQLDFQMPERFNLNYVGEDGQKHRPVMIHRVVFGSIERFIGILTEHFAGAFPVWLAPVQVKVLPITDRHHEYARELVKRLQGLDIRVELDARNEKINYKIREAQTQKIPYMLVIGDREMEQGAVAVRERGKGDVGAISVGDFIKKIEDDIQNKTI
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U76F2_ARATH
Sequence: MEERKVKRIIMFPLPFTGHFNPMIELAGIFHNRGFSVTILHTSFNFPDPSRHPQFTFRTITHKNEGEEDPLSQSETSSGKDLVVLISLLKQYYTEPSLAEEVGEGGTVCCLVSDALWGRNTEIVAKEIGVCTMVMRTSGAATFCAYTAFPLLIDKGYLPIQGSRLDELVTELPPLKVKDLPVIKTKEPEGLNRILNDMVEGAKLSSGVVWNTFEDLERHSLMDCRSKLQVPLFPIGPFHKHRTDLPPKPKNKDKDDDEILTDWLNKQAPQSVVYVSFGSLAAIEENEFFEIAWGLRNSELPFLWVVRPGMVRGTEWLESLPCGFLENIGHQGKIVKWVNQLETLAHPAVGAFWTHCGWNSTIESICEGVPMICTPCFSDQHVNARYIVDVWRVGMMLERCKMERTEIEKVVTSVMMENGAGLTEMCLELKEKANVCLSEDGSSSKYLDKLVSHVLSFDSSAFAS
What are the official names of this protein?
UDP-glycosyltransferase 76F2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: RS17_NITMU
Sequence: MSEANLNRTLSGKVVSDKMNKTITVLVERKVKHPLYGKIMVRSKKYHVHDEANEFHTGDVVVIEECRPLSKTKAWRVVKLMQKAEQVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SH3G3_DROVI
Sequence: MAFAGLKKQINKANQYVTEKMGGAEGTKLDLDFMDMERKTDVTVELVEELQLKTKEFLQPNPTARAKMAAVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKYSLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAKDDEIRGAEDKFAESLQLAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQETLQEKRAEAESRPRNEFVPKTLLDLNLDGGGGGLIDDGTPSHISSSASPLPSPMRSPAKSMAVTPNRQQQPCCQALYDFDPENPGELGFKENDIITLLNRVDDNWYEGAVNGRTGYFPQSYVQVQVPLPNGN
What is the function of this protein?
Required presynaptically at the neuromuscular junction.  Implicated in synaptic vesicle endocytosis.
What are the official names of this protein?
Endophilin-A, SH3 domain-containing GRB2-like protein.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Associated with internal membranes. Expressed presynaptically at NMJs.
Protein: MEP3_ARTBE
Sequence: MHGLLLAGLLALPMNVLAHPAEQHASNVLSRRGVDIESFRLPLKAKYMDSDAAAQKIQAMSFSKDDDYVSTATKLVKSTFPKSTFRVVDDHYIGTNGIGHVHFKQTAHGLDIDNSDFNVNIGRDGKVFSFGNSFFTGEIPKENPMVKRAFSDPVKALKGAVKALNLPVKSDNAKAKTTAGKESFEFMGTTGALSAPKANLVYLQKEDGTLALTWRVETDVGDNWLLTYVDAHNSETVHNVVDYVASAEFKVFAWGLNDPTEGNPTSIRDPWTDSSPYTWHSDGMTKYPTTRGNNAIAQDNPTGGSTYINNYRPQSPNLIFNYPWSPTATPPSSYKDFSITQLFYTTNRFHDLLYSFGFNEAAGNFQVNNGNKGGRGNDFAIVNAQDGSGTNNANFATPPDGSPGRMRMYNWTTARPNRDGCLEAGIVIHEYAHGLSNRLCGGPANSGCLNALESGGMGEGWGDFYATAIRLKPRDTKDTNYSMGAWAANNPKGIRAYLYSTNLQTNPYMYTSVNSLREVHQIGTVWATMLYDLMWALIEAHGGTYSANPVFRNGVPQDGRHLAMKLVMDGMALQPCNPNFVQARDAILDADRALTNSANKCTIWKAFAKRGLGYGAKYDARNRTGSNRLPPGC
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 3, Fungalysin MEP3.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNC_STAAT
Sequence: MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_HALSA
Sequence: MEFQDFLLAASTGDLGAAPAAPEHVDLVEFRMDLAADPLAALDDYDGVLPVLATNRADWEGGAAADGGDRIDALAEAARTDCVAAVDIERSALVDDDTADGAEALAAARSTDTTTVVSAHDFDGTPSLSAMADLLGEACSLGDVGKLAVTPQDRGDALDVIRVTHEYSAAGMTVATMGMGDLGRHTRAVTPLYGSKLGYAPVADGETTAPGQYAPAALQALIADLQ
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: ASSY_RHOJR
Sequence: MADRVVLAYSGGLDTSVAISWIGKETGKEVVAVAIDLGQGGEDMEVVRQRALDCGAVESVVVDARDEFADEYCLPTIQANALYMDRYPLVSAISRPLIVKHLVEAARAHGGTTVAHGCTGKGNDQVRFEVGFGSLAPDLDVIAPVRDYAWTREKAIAFAEENEIPINVSKKSPFSIDQNVWGRAVETGFLEDLWNAPTKDVYDYTQDPTVNWQAPDELIISFEAGRPVAIDGKPVSVLEAIQELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLINAHQELEHVTQERELGRYKRQTEQRWSELVYDGLWFSPLKVALDTFIEKTQERVSGDIRLVLHGGAIIVNGRRSNESLYDFNLATYDEGDTFDQSYAKGFVQIHGLSSKVAAKRDLGL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MK04_RAT
Sequence: GCGGNGLVLSATDSRACRKVAVKKIVLSDARSMKHALREIKIIRRLDHDNIVKVYEVLGPKGSDLQGELFKFSVAYIVQEYMETDLACLLEQGTLTEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIADQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGKMLFAGAHELEQMQLILDTIPVVREEDKEELLRVMPSFVSSTWEVKRPLRKLLPDVNREAIDFLEKILTFSPMDR
What is the function of this protein?
Atypical MAPK protein.  Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5.  The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4.  May promote entry in the cell cycle (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase 4, MAP kinase 4, MAPK 4, Extracellular signal-regulated kinase 4, ERK-4, MAP kinase isoform p63, p63-MAPK, MNK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the cytoplasm following interaction with MAPKAPK5.
Protein: DAPA_THEMA
Sequence: MFRGVGTAIVTPFKNGELDLESYERLVRYQLENGVNALIVLGTTGESPTVNEDEREKLVSRTLEIVDGKIPVIVGAGTNSTEKTLKLVKQAEKLGANGVLVVTPYYNKPTQEGLYQHYKYISERTDLGIVVYNVPGRTGVNVLPETAARIAADLKNVVGIKEANPDIDQIDRTVSLTKQARSDFMVWSGNDDRTFYLLCAGGDGVISVVSNVAPKQMVELCAEYFSGNLEKSREVHRKLRPLMKALFVETNPIPVKAALNLMGFIENELRLPLVPASEKTVELLRNVLKESGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_I69A0
Sequence: MDVNPTLLFLKVPVQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDRLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRVNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITKNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLASIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYEAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: RL17_ECOSE
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.