PharMolix/UniProtQA huggingface dataset:
Protein: FPG_MYCPN
Sequence: MPELPEVATVITELKSCVLNKPVKQVKVHLDKVLKNTNVKQLNDALVNHSFVDIKRRGKYIIFCLSNGLFLVSHLRMEGKYFFEAKGSQFDLNHVLVEFLFQDGDQLNYHDTRQFGTFHLFNRYQFENARELNKLALDPLDQEFNHQAIFNKGHKSNKKIKTFILDQTNISGIGNIYADEILFASKIHPETLAKNLNLSQYQLICQNATDILKKAVEMKGTTIGTFTFKKDHTGGYQHFLKIHGKKGKQCQSCNTTIIKKKINGRGSYICEKCQIQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: CTLP1_ODOSH
Sequence: GCDLSTCATHNLVNELNKFDKSKPSSGGVGPESP
What are the official names of this protein?
Calcitonin-like peptide 1, OsCTLP-1.
Protein: HYPA_IGNH4
Sequence: MHEASYALTIVDTVMEALKKEGLENVKVTKVIIKIGELSLVDPVALRNAFEAYSLGSPLEGAELEIEVVPSKFVCKRCGHEWTFKDVYPELKANIPVIHLYPHLVKDLLKCPKCNSSEVEIVQGTEFVIEGFEYQESNE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: PYLAA_XENLA
Sequence: MYKQIFLCLIIAALCATIMAEASAFADADEDDDKRYVRGMASKAGAIAGKIAKVALKALGRRDS
What is the function of this protein?
PGLa and PGLa-H display a broad-spectrum of antibacterial activity against a range of Gram-positive and Gram-negative bacteria.  PGLa also displays antifungal activity against C. albicans ATCC 14053.  PGLa-H shows moderate antibacterial activity against the multidrug-resistant methicillin-resistant S. aureus (MRSA) but exhibits very little hemolytic activity.
What are the official names of this protein?
PYLa/PGLa A.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family. Magainin subfamily.
Protein: METN_BACSU
Sequence: MINLQDVSKVYKSKHGDVNAVQNVSLSIKKGEIFGIIGYSGAGKSSLIRLLNGLEKPTSGTVEVAGTKINEVNGRGLRKARHEISMIFQHFNLLWSRTVRDNIMFPLEIAGVKKSERIKRANELIKLVGLEGKEKSYPSQLSGGQKQRVGIARALANNPKVLLCDEATSALDPQTTDSILDLLSDINERLGLTIVLITHEMHVIRKICNRVAVMENGKVVEEGEVLDVFKNPKEQMTKRFVQQVTEPEETKETLQHLLDDTASGKMVQLTFVGESAEQPLITEMIRNFNVSVNILQGKISQTKDGAYGSLFIHIDGDEEEVQNVIRFINDKQVKAEVITNV
What is the function of this protein?
Part of the ABC transporter complex MetNPQ involved in methionine import (PubMed:14990259).  Responsible for energy coupling to the transport system (Probable).  It has also been shown to be involved in methionine sulfoxide transport (PubMed:14990259).
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PALY_CAMSI
Sequence: MDSTTAIGNGVGSGGSPGFCLKDPLNWGVAAEAMKGSHLEEVKGMVEEFRKPVVRLGGETLTISQVAAIAVRGSEVAVELSESAREGVKASSDWVMESMNKGTDSYGVTTGFGATSHRRTKEGGALQKELIRFLNAGIFGNGTESCHTLPQSATRAAMLVRINTLLQGYSGIRFEILEAISKFLNNNITPCLPLRGTITASGDLVPLSYIAGLLTGRHNSKAVGPTGEILHPKEAFRLAGVEGGFFELQPKEGLALVNGTAVGSGLASMVLFEANILAVLSEVLSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPLIEVIRSSTKSIEREINSVNDNPLINVSRNKALHGGNFQGTPIGVSMDNTRLAVASIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMAAYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTAEAVDILKLMSSTYLVALCQAVDLRHFEENLRNTVKSTVSQVAKRVLTMGVNGELHPSRFCEKDLLRVVDREYIFAYIDDPCSATYPLMQKLRQVLVEHALKNGESEKNLSTSIFQKIRAFEEEIKTLLPKEVESTRAAIENGNSAIPNRIKECRSYPLYKFVREELGTELLTGEKVRSPGEEFDKVFTALCKGEMIDPLMDCLKEWNGAPLPIC
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_PSESM
Sequence: MILELDCGNSFIKWRIITKSCSTLVSGGVVDSDTALLECLGNLSGAAFSDCRLVSVRSAEETAKLVCALADTFSISPVCAAPAPELAGVINGYDDFARLGLDRWLAFVGAYHLVKGACLVIDLGTAITSDFVEASGKHLGGFICPGMPLMRNQLRTHTRRIRYDDAEAEKALVRLVPGRATAEAVERGCSLMLRGFAMTQIEIAREYWGDDFAIFVTGGDAVLVADVLPGARIVPDLVFVGLALACPLR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECS_VATGU
Sequence: SEVVSFSFTKFNPNPKDIILQGDALVTSKGKLQLTKVEDGEPVDHSLGRALYVAPIHIWDDSTDRVASFATSFSFVVEAPDESKTADGIAFFLAPPDTQPQKNGGFLGLFNDSNKSIQTVAVEFDTFSNTWDPSARHIGINVNSIESQKYVKWGWEDGKVANVYISYQASTKTLTASLTYPSNATSYIVSANVDLKSALPEWVRVGFSATSGLSRDHVETHDVLDWSQTSTPAANSDYT
What is the function of this protein?
D-galactose-specific lectin.  Has Ca(2+) and Mn(2+)-independent hemagglutinating activity towards rabbit erythrocytes.  Has an epithelium-dependent vasorelaxant effect in vitro.
What are the official names of this protein?
Seed lectin, VGL.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: LEUC_CLOK5
Sequence: MAMTMTQKILASHAGLDSVKSGELIKVKLDLVLGNDITTPVAINEFNKIGSNKVFHKEKVAIVPDHFTPNKDIKSAEQCKCVREFAKDKDIKNYFEIGQMGIEHALIPEKGLAVCGDVIIGADSHTCTYGALGAFSTGVGSTDMAAGMATGEAWFKVPEAIKFVLNGKLSPWVSGKDIILHIIGMIGVDGALYNSMEFTGEGVGELSMDDRFTIANMAIEAGAKNGIFPVDEKTIEYVKEHSNRSYTVYEADEDAEYVKTIEIDLSKIPPTVAFPHIPENTRTIDEVGEIKIDQVVIGSCTNGRIGDLRVAAKVLKGRKVNSNVRTIIFPATQSIYLQAMKEGLLEIFIESGAVVSTPTCGPCLGGHMGILAKGERAVATTNRNFTGRMGHVESEVYLASPAVAAASAVTGKISSPEEVV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: NU2M_XENLA
Sequence: MNPITFSVVLTSLASEQFLAVSSSHWLLAWMGLEINTLAIIPLMTQHKHPRAIEASTKYFLTQAAASALLLFSSLNNAWLTGEWSILDLTNPLSCATMTIAICMKLGLAPFHFWLPEVLQGLSLTTGLILSTWQKLAPMAILYQIAPMLNTPLLLTLGLTSTLIGGWGGLNQTQLRKILAFSSIAHLGWMISILPFSPQLMILNLTIYLIMTSTMFLVLKTISSTKISSLATSWSKTPSTTALSLLTLLSLGGLPPLSGFVPKWFIIQELTSQNTTILATTLALSALLSLFFYLRLTYIVTLTSSPNTSNASLTWRHHSKQPTLLLSIALILSSFIIPISPLTLT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FTSW_THICA
Sequence: MANTWRLDIRGLDGSLVLIVLALITIGLVMVLSSSVAVSEVRFGHQWHYFQRQVFALGVGGLFAALVLMVPSQSWLQHRGKWFLLGLVLLALVLIFGREIGGAKRWLPLVVMNFQPAEWMKIATILFLAGYLQRHQDAVKQDSTAVIRLFLPFGIMAGLLLLQPDYGTTVLIAGVLVGMLFIAGAPFRYFVITVLPIGAILAVLLINSPYRMARVMNFMDPWQDPYGVGYQLSQALMAIGSGGITGSGLGASVQKLLYLPDAHTDFMFAVFAEETGWLGVVILLSLYGLLLWRMFAVAQAAWLPQAPFKALVVYGVAIMFAGQLLINVGVNLGVFPTKGLTLPFVSYGGSSLMMALLAIGLVLRIDYETRLIKGHSTEELSANPSFGS
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: FDHD_KLEP3
Sequence: MNKKPLEQIKNVTNVTGYRQVSLWKREDLQHPQPDELAEEIPVALVYNGISHVVMMATPKDLEQFAVGFSLSEGIIEHRREIFGMDVVSVCNGLEVQIELSSRRFMGLKARRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLANLDHSLAHLNDFQPVGRLTGCTHAAAWVRTTGELAGGFEDVGRHVALDKLLGQRAEIGEDWQHGAALVSSRASYEMVQKAAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLIAG
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_STRE4
Sequence: MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQVVLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMELSKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFANAIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEYEVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALKIEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDMLNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEECLLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAGLTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRRLRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIELEQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQPPGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEHPVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQDKIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVATKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSDLTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAAFFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQGVPLFTALDTAVAMLRVLESRTFSIEAI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: SEPF_BIFAA
Sequence: MAGFMKNAMSYLGMSDVAEGEDDFEDDVDTGETSFDSDHSVTPMPSSSASASTPSAPREQSNPFQGGRVSRITTIHPKTYDDAQMVGRAIRDGIPVVLNLTGVAEAVAYRIVDFSAGVVFGVRGSIERVTPRVFLLSPAQVNIKVEEPEDKGPAHDLFAD
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: SUCC_PSECP
Sequence: MDLFEYQARDMFEAHGVPVLAGIVAYTPEEAKAAAEKIGGVTVVKAQVKVGGRGKAGGVKVAKSADEALEHSTNILGMDIKGHTVNKVMIAQGADIAEEYYFSVLLDRANRNYLAMCSVEGGMEIEQLAVERPEALAKIAIDPAVGIDQAKADEIVAAAGFAEELRGKVADVILKLWDVFKKEDATLVEVNPLVKTGAGDIVALDGKVSLDENAEFRHAKHAQLEDKDAADPLEAKAKAQDLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGENHGNVKPANFLDIGGGASAEVMAAGLDVILGDEQVKSVFVNVFGGITACDAVAKGIVGALAELGHTANKPLVVRLDGNNVEEGRRILNEANHPLVTLAATMDEGADKAAELANAAK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: SPEA_PROMA
Sequence: MTKSKPATKKNEWTVKDSCSLYGLDLWGEEYFSINDSGNVTVSPQGKEGNSLELTHLLEELKGRNLNTPLLLRFDDILEDRLKKLHQAFENAINQYGYNNDYQGVFPIKCNQQRHVVEEIVTIGRKWHFGLEAGSKAELLIALALVNDPKAFLICNGYKDNRYIETTILARQLGRQPIVVIEQSDEVGRIIKASQKLGAAPLIGIRAKLSNQSSGRWGNSVGEKSKFGLSIPEILKAVQELTAAGLLNELILLHFHVGSQINDIAILKNALQEASQIYVELNRLGAPMGHLDVGGGLGVDYDGSRTATSASTNYSLQNYANDVVATIQECCKAKKVKVPKLISESGRFLSSHFSILIFNVLGTSSVPTQIAIETSNECLSVKNLRETLMILHQICEEKKIDVSKLQEAWNDALKFKEDALNAFRLGFIDLTERATAEQLTWACAKQIAAHLPNDLKIPKELLAINKGLTETYYANISIFRSAPDTWAIQQLFPLLPIHRLQEKPDQLGHFADLTCDSDGKLARFINNGQEKFLLELHTVKANENYWIGMFLGGAYQEVMGNLHNLFGSTNAIHIRLTKNGKYKLDHVVRGNSKSDVLQAMEHDSEQLLERIRMASESAIQQGSLKINDAQRLIEHVETSLRQSTYLQE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: V5_SPTNK
Sequence: MSNITYEFNENDVIVNNNGMPCIQRPFDKEALYSLLDKMSKEQLDELIEDINDEKRLREFKEEKLKKVRSRMNRELKIYKQELENKKQRMKMLTEQEEEEEEEEEEPPKPKKKVINRKK
What are the official names of this protein?
Uncharacterized protein V5.
Protein: Y1920_ACIF2
Sequence: MKGGLGNIMKQAQQLQERLQKTQEELAQVEVQGHAGGNLVEVTMTCRHDVRRVRIDPSLLTDGDQEMLEDLVAAAINDAVRTAEKVSAERMSEVTGGMNIPGMNLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein AFE_1920.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YFEW_ECO57
Sequence: MKRTMLYLSLLAVSCSVSAAKYPVLTESSPEKAGFNVERLNQMDRWISQQVDAGYPGVNLLIIKDNQIVYRKAWGAAKKYDGSVLMAQPVKATTGTLYDLASNTKMYATNFALQKLMSEGKLHPDDLIAKYISGFADSPNDTIKGKNTLRISDLLHHSGGFPADPQYPNKAVAGALYSQDKGQTLEMIKRTPLEYQPGSKHIYSDVDYMLLGFIVESVTGQPLDRYVEESIYRPLGLTHTVFNPLLKGFKPQQIAATELNGNTRDGVIHFPNIRTSTHWGQVHDEKAFYSMGGVSGHAGLFSNTGDIAVLMQTMLNGGGYGDVQLFSAETVKMFTTSSKEDATFGLGWRVNGNATMTPTFGTLASPQTYGHTGWTGTVTVIDPVNHMAIVMLSNKPHSPVADPQKNPNMFESGQLPIATYGWVVDQVYAALKQK
What are the official names of this protein?
Putative D-alanyl-D-alanine carboxypeptidase, DD-carboxypeptidase, DD-CPase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family. YfeW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: COAD_BRUO2
Sequence: MTIAIYAGSFDPVTNGHIDVLKGALRLADQVIVAIGMHPGKKPLFSFDERVALIEASAKAVLHKDAARVSVIAFDGLVIDAARKHGAQLMVRGLRDGTDLDYEMQMAGMNGTMAPELQTVFLPADPAVRTITATLVRQIASMGGDIKPFVPVAVAAALNTKFKS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_SHEHH
Sequence: MDKRHDPSRRIIAPTGTKLSCKSWLTEAPMRMLMNNLHPDVAERPEDLVVYGGIGRAARDWECYDKIVEVLQRLEDDETLMVQSGKPVGVFKTHSNAPRVIIANSNLVPHWANWEHFNELDKKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVAMAKQHFNGVSAGKWILTGGLGGMGGAQPLAGTMAGYSVLTCEVDETRIDFRLRTKYVDKKATSLDEALAMIEEANNSGKPVSVGLLANAADVFAELVERGITPDVVTDQTSAHDPLNGYLPQGWTLEYAAEMRKKDEAAVVKAAKQSMAVQVKAMLALQAAGAATTDYGNNIRQMAFEEGVENAFDFPGFVPAYVRPLFCEGIGPFRWVALSGDPEDIYKTDAKVKELIPDNPQLHNWLDMARERIAFQGLPSRICWVGLKDRARLALAFNEMVKNGELSAPIVIGRDHLDSGSVASPNRETESMLDGSDAVSDWPLMNALLNTASGATWVSLHHGGGVGMGFSQHSGVVIVADGTDDAAVRLGRVLWNDPATGVMRHADAGYDIAKNCAKEQGLDLPML
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKT_RHOCA
Sequence: MDLAALRAKTPDHWKLATAIRVLAIDAVQAANSGHPGMPMGMADVATVLFRNHLKFDAKAPNWADRDRFVLSAGHGSMLLYALLHLTGYEQATLDEVKNFRQWGARMAGHPEYGHLEGVETTTGPLGQGISTAVGMAIAEKSMAARFGKKLVDHKIWVIAGDGCLMEGISQEAIGLAGKQELDNLIVLWDNNNITIDGRVTVSDVTDQKARFAASGWDVLSCDGHDAEDIDRALTAAKKAKRPVLVDCKTLIGFGSPNKADSYAVHGAPLGDAEIKLTREAYGWEHGPFVIPAEIKAEWEAIGAKGAAERAEWEARLAALPAGKRAEFERQMARGVAPKLAGAIRAFKKAQSEAAPKVATRKASEMVLAAVNPVVLRNHRRLADLTGSNLTKTSDIEDFMPGNHKGRYMRYGIREHAMAAAMNGMWLHGGVRPYGGTFFCFTDYARGAMRLSSLMGVPTVYVMTHDSIGLGEDGPTHQPVEHLTICRATPNTWTFRPADVIETAEAWELALSSERTPSVLALSRQNLPTLRTKHEAKNLTAKGAYVIAEAEGKRQAILMATGSEVEIALKARALLQAEAIGTRVVSMPCMELFAAQDEAYRKRILPAGGVRVAVEAAIRQPWDRWLLGERGMERKAGFVGMEGFGASAPAERLYAEFGITPEAIAAKVKSLL
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase, TK.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: THIC_PORGI
Sequence: MKEFKVTTGPLPGSEKIYVEGERFPFLRVPMRRIRMSDTILENGEREKNEDVVVYDTSGPYTDTSYEVNLHRGVPKIREQWIEDRGDTVRLEGLSSEYGRIRQSDASLEKLRYEHVCTRPRAAKDGCATQLYYARQGIVTPEMEFVAIRENQLIDQVRTRYRAEEGEPLGAVIPRKITPEFVRDEIAAGRAILPANINHPESEPMIIGRNFLVKINANIGNSPISSTIEEEVEKAVWAIRWGADTVMDLSTGDHIHETREWIIRNSPVPIGTVPLYQTLEKVQGDVTKLNWEIFRDTLIEQAEQGVDYFTIHAGLRWHHVPLTLRRLTGIVSRGGSIIANWCTTHKRESFIYEHFEEICQILARYDVAISLGDGLRPGCIHDANDAAQIAELKTLGELTEIAWKYNVQTIIEGPGHVPMHKIRENMEIQLEACHGAPFYTLGPLVSDVASGYDHITSAIGAAQIGWFGTAMLCYVTQKEHLGLPNREDVREGVVTYRLAAHAADLAKGHPTAYWRDYMMSKARFEFRWKDQFHLSLDPEKAIQFHDATLPDEGHKEAHFCSMCGEHFCSMRANKNFRKLLNEEAVSK
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: MNMA_SALAR
Sequence: MSESPKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLEEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRVDINGKSRLLRGLDGNKDQSYFLYTLGHEQIAQSLFPVGELEKPQVRKIAEDLGLITAKKKDSTGICFIGERKFRDFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKDGSEDPWYVVDKDVENNVLIVAQGHEHPRLMSSGLIAQQLHWVDREPFTGTLSCTVKTRYRQTDIPCTINALDDDRIEVIFDEPVAAVTPGQSAVFYSGEVCLGGGIIEQRLPLTV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_STAAN
Sequence: MRKIQAKKGLSIECKGWEQEAVLRMLYNNLDPEVAERPEDLVVYGGIGKAARNWEAFEAIEKTLRELESDETMLVQSGKPVAVFKTHEEAPRVLISNSVLVPEWANWDHFNELDKKGLIMYGQMTAGSWIYIGSQGIVQGTYETFAELGNQHFNGDLAGTVTLTAGLGGMGGAQPLAITMNHGVAICVDVDETRVDKRIDTKYCDVKTADLDEALKLAEEAKERGEGLSIGLVGNAVDIHQAILEKGFKIDIITDQTSAHDPLNGYVPQGYSVEEAKVLREKDPKKYVELSQASMAKHVELMLEFQKRGAVAFDYGNNIRQVAFNNGVKNAFDFPGFVPAYIRPLFCEGKGPFRFAALSGDPKDIERADEEMRKLFPENEKLLRWLDLAEEKISYQGLPSRIAWLGYGERAKMGLALNRLVRDGEISAPIVIGRDHLDAGSVASPNRETESMKDGSDAVGDWAVLNALINTAAGGSWISFHHGGGVGMGYSLHAGMVVVADGSERAERRLERVLTTDPGMGVARHVDAGYDIAIQTAKEKGIHIPMIDKAGDK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXR4B_XENLA
Sequence: MDGFSGGIDINIFDGNSTENGSGDFEDFIEPCFMQENSDFNRIFLPTIYSFIFLLGIIGNGLVVVVMGYQKKSRTMTDKYRLHLSVADLLFVFTLPFWSVDAAIGWYFKEFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQGSRKMLADKVVYAGVWLPALLLTVPDLVFASVSNENGQFVCDRIYPIDNRETWTVGFRFLHITVGLILPGLIILVCYCVIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYVCLTTDTFMMLGLVKADCIWENTLHKAISITEALAFFHCCLNPILYAFLGAKFKKSAQNAFTSVSRGSSLKILSKKRAGLSSVSTESESSSFHSS
What is the function of this protein?
Receptor for the C-X-C chemokine cxcl12/sdf-1.  Transduces a signal by increasing the intracellular level of calcium ions.  Signaling with cxcl12/sdf-1 mediates the directional movement of mesodermal cells during gastrulation.  May play a role in the migration of embryonic presumptive primordial germ cells (pPGCs).  May also be involved in regulating migration of hematopoietic stem cells into the larval liver (By similarity).
What are the official names of this protein?
C-X-C chemokine receptor type 4-B, CXC-R4-B, CXCR-4-B, Stromal cell-derived factor 1 receptor B, SDF-1 receptor B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Early endosome. Late endosome. Lysosome. Note=Expressed in the cytoplasm of a small number of embryonic pPGCs from stage 24. Expressed in the nucleus of 3 lateral pPGCs (By similarity).
Protein: RPOC_DESHY
Sequence: MKGERTVLDVNNFDRMRIGLASPTMIREWSHGEVRKPETINYRTLKPEREGLFCEKIFGPTRDWECHCGKYKRVRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRSLEKVLYFVSYIVTDAGDTSLMKKQLLTETEYREYRDKYGSRFKASMGAEAIKMLLEEMDLDKLNDELRVELKEVSGQRKIRAIRRLEVVEAFKESGNRPEWMIMDVVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLRLHQCGLPKEMALELFKPFVMKKLVKEGHAHNIKSAKRMVERVRSEVWDVLEEVITEHPVLLNRAPTLHRLGIQAFEPVLVEGRALQIHPLVCTAYNADFDGDQMAVHVPLSAEAQAEARLLMLSAHNILNPKDGRPVASPTQDMVLGSYYLTMERPGALGEGKIFKNRDEAVLAYDTKQANLQAMIKVRQPNGELLETTIGRLIFNSVIPPEVGYINEVAGKKALNNIVAKCYRLGGYKATAQLLDGIKSLGFKYSTRAGMTVGLADITVPEEKRQILADADGMVNKTEQQFRRGLITDEERYEKVIDIWTKATDTVTKALMHSLDKFNPVYMMATSGARGNIQQLRQLAGMRGLMADPSGRTIELPIKANFREGLTVLEYFISSHGARKGLADTALRTADSGYLTRRLVDVSQDVIVRDEDCGTTQGIMVDDVKDGPEVIEKLEERLVGRFLLEDLKHPETGEILATADNEITEEQAHDIAEVYDKVTIRSVLTCKTRYGVCRKCYGRNLATGHHVEMGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVEELFEARKPKGQAIISENDGVVAIREVKGRREVDVISDTEERMTYTIPYGSRLKVREGHRIEAGDELTEGSINPHDMLKVKGIRGVQVYLLGEVQRVYRLQGVDINDKHIEVMVRQMLRKVKVEEAGDTTLLPGGLIDVFDFEEENTKVIAAGGEPAVARPVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKVDPLLGLKENVIIGKLIPAGTGMSRYRNVKVINLDEEQVENLDSVNP
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.