PharMolix/UniProtQA huggingface dataset:
Protein: NIFB_KLEOX
Sequence: MTSCSSFSGGKACRPADDSALTPLVADKAAAHPCYSRNGHHRFARMHLPVAPACNLQCNYCNRKFDCSNESRPGVSSTLLTPEQAVVKVRQVAQAIPQLSVVGIAGPGDPLANIARTFRTLELIREQLPDLKLCLST
What is the function of this protein?
Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms.  NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.
What are the official names of this protein?
FeMo cofactor biosynthesis protein NifB, Nitrogenase cofactor maturase NifB, Radical SAM assemblase NifB.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. NifB family.
Protein: MEQ_GAHVM
Sequence: MSQEPEPGAMPYSPADDPSPLDLSLGSTSRRKKRKSHDIPNSPSKHPFPDGLSEEEKQKLERRRKRNRDAARRRRRKQTDYVDKLHEACEELQRANEHLRKEIRDLRTECTSLRVQLACHEPVCPMAVPLTVTLGLLTTPHDPVPEPPICTPPPPSPDEPNAPHCSGSQPPICTPPPPDTEELCAQLCSTPPPPISTPHIIYAPGPSPLQPPICTPAPPDAEELCAQLCSTPPPPICTPHSLFCPPQPPSPEGIFPALCPVTEPCTPPSPGTVYAQLCPVGQVPLFTPSPPHPAPEPERLYARLTEDPEQDSLYSGQIYTQFPSDTQSTVWWFPGDGRP
What is the function of this protein?
Functions as a DNA-binding transcription factor.  Promotes transformation, host cell growth, host cell-cycle progression through G1/S phase, and possesses antiapoptotic activity.  Forms functional heterodimers with host JUN.  These heterodimers bind with high affinity DNA sequences called MEQ-responsive elements MERE I (TGACA/GTCA), while MEQ homodimers bind a second type of sites termed MERE II (ACACA).  Both homo and heterodimerization of MEQ are required for oncogenesis.
What are the official names of this protein?
Oncoprotein MEQ, MEQ.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Jun subfamily.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Note=Expressed in both the nucleus and the cytoplasm during the G1/S boundary and early S phase of host cell cycle.
Protein: KMO_ASPOR
Sequence: MAQEPPRKQKVVIVGAGPVGSLAALYAAARGDDVEVYELRGDLRDPTTIPLNFTKSINLALSERGISSLKGSNRDGMIEKILNDAIPMHGRMIHGRDDGKLWEAAQAYDVHGQAINSVDRSTLNNALLDELERTPNVKLFFNHKLTGADFQSNRAWFERRAPGDTPLPGSSNRVPEIEVSFDYMIGADGAHSASRYHMMKYSRVDYQQEYIDTLWCEFRIPPSDTGDFRISPNHLHIWPGKEFMFIALPSPDKSFTCTLFAPAAHYAQLESSPQKLFLSFDANFPGVSPDLITPEDLQEQFKENPHLPLISIKAKPHHYGSNIVIVGDAAHAILPFYGQGLNAGLEDIRVLFDFLDKHDAFDLNASLTARRESRRAAFQAYTDQRTADAHAINDLSKQNYLEMRWGVKTPLYKIRKSIEEALDLYVPSLGWKTQYARVSFSTQRYSDVVKVVHRQGRILGYGFASAVISSITIAGILAWKIPGRLSPLPALQSTVQLLGHVWTKISPKNT
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Biosynthesis of nicotinic acid protein 4, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: RPB11_MOUSE
Sequence: MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRGAIKDKQEGIE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB11 is part of the core element with the central large cleft (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB11, RNA polymerase II subunit B11, DNA-directed RNA polymerase II subunit J, RNA polymerase II 13.3 kDa subunit, RPB14.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL34_ENCCU
Sequence: MKNVLIHKGATYKTRSNRRRKVRTPSGKLVNRRVKKHSKKHRCHECNAILGSIARMRPAEFSRQKVSARRVNRPYGATTCGRCVREKIISAFLGNEERIVMEKTGAAAGG
What are the official names of this protein?
60S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: RBSD_STAAM
Sequence: MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPA_SHESM
Sequence: MPFALGQRWISDTESELGLGTVVQVEGRMVTVLFPATGENRMFSRNEAPLTRVIYNPGDTVESHEGWSLAIEELTEKDGLVVYHGIHSETGEKASLRETLLNHNIRFNKPQDRLFAGQIDRLDRFGIRYQCQLLRHQLATSDLLGLQGPRVGLIPHQMWIAHEVGRRYAPRVLLADEVGLGKTIEAGLIIHQQLLTGRAERVLIIVPDTLRHQWLVEMLRRFNLRFSVFDEDRCVEAFADHDNPFYTEQLVICSLELLRKKKRLDQALDADWDLLVVDEAHHLEWTEEAPSRAYQVVEALSEVVPGVLLLTATPDQLGHESHFARLRLLDPDRFYDYDAFLAEENSYKDVAVAAEALAGDAKLSDAAINSLTELLSEKDIAPSIRLIQAEDIDSELQQAARSELLQELLDRHGTGRVLYRNSRASVKGFPKRIFNAYPHAMPEQYLTAARVNEMMGGRKTLEAKAAQALSPEKLYQEFEDNSASWWKFDPRVDWLIEFLKSHRSKKVLIIASGADTALSLEEALRTREGIQATVFHEGMSIIERDKAGAYFAQEEGGAQALICSEIGSEGRNFQFASHLVLFDLPLNPDLLEQRIGRLDRIGQKNDIQIHLPYLQDTAQERLLNWYHQGLNAFELTCPSGHVLYSEFAEDLLNVLVGGDEDELTNLLNHTQSRYKELKHAMEQGRDKLLEINSHGGDKAKAIVERLAQSDQDTKLIGSVIRLWDIIGVDQEDKGENSIILRPSEHMMFPTYPGLHEDGVTVTFDRDTALSRDDIALITQEHPLVQTGLDLITGSDTGTTSVAILKNKALPAGTLFLELIYMADASAPKSSQLYRYLPPTPIRVLLDKNGNDLSAKVDYTSFDKQLSAVNRHIGSKLVTASQPILHPLFAKGEEYAQAAVDELVAQAREKMTSQLTGELDRLESLKAVNPNIREEELEYLRNQMQELSTYLNASQLQLDAIRMVLVSHV
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: Y9452_DICDI
Sequence: MYIYINNEIEELIECAKKIPILNNNENGNDHNKSISKLITIFKSKQRSRSSSFSLDTLNFNLSSSSSNSIEIDDENPYNTNNNNNSNNNNNNNNNNCNNSNNSNNNKNINSLDNIDINNNNKNNFNDCSSYSSFSSSECLSDIGNSCIDSLELFRLSDDIEEESEMIFNQVGPDRYNDLANIFSKSHKNLTILLKDINRDTLDCSECIDGSLSDNEWEKCLCCGDIHSLGDYKHVECIGKGGYGVVCKFINKKTNEIRAIKTIRKDYSALKEINTLKELGGQFTVNIFHTFLSPCKEKVLIEMEYLSGGDCAFHLNDVGVGFPEELAKQYTAETVLCLDFIHEKSIIHCDIKPNNMVIDSDGHIKLLDFGNAKKFNQKKPTSNDGILGSPRYISPEVLLFEPQSPAVDYWSLGIVMFELITGTTPFIGETPEEIFESILSRNTECIEIQKDAKDLIIKLLDPNPSTRIGSKDIKNHPYFNGINWDTIKTSQPIWKPNSSNNFITSINGCCKLINSF
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0293276.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Protein: EFP_DICNV
Sequence: MATFSTNEFRGGLKIMLDGDPYTIVENEFVKPGKGQAFNRTKVRNLKTGRVLERTFKSGESVEAADVLEMNMQYLYKDEDNWYFMNPETFEQLPAAQAAVADAEKWLLEQDECTVVLWNNNIISVTPPNFVERKIVDTDPGLRGDTSGGGGKPATLETGAVVRVPLFLNIGDTIKVDTRSGEYLGRAKE
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPIP_BPT4
Sequence: MEGLIEAIKSNDLVAARKLFAEAMAARTIDLIKEEKIAIARNFLIEGEEPEDEDEDEDDEDSDDKDDKKDEDSDEDEDDE
What is the function of this protein?
The production of one phage particle requires 250 copies of PIP.  During head maturation, PIP is cleaved to form the stable head constituent, internal peptide II.
What are the official names of this protein?
Prehead core component PIP, Protein Gp67.
Protein: DXR_FRATO
Sequence: MFKKTKITILGATGSIGDSTLAVIRETNDFEVFALTAFSNVEKLAELCQEFKPKFAVVPDLSKKQKLQSLVTDVEVLVGESGLEKVSSLAEIDIVMSAIVGIAGLKPTFAAAKAGKKILLANKESLVTAGHLLIDEVVKNNAQLIPVDSEHNAIFQCIDNHDKKCLPEIDKIILTASGGPFRDKQQLHELTDVTPEQACNHPNWQMGRKISVDSSTMVNKALEVIEAYWLFSVSADKIGVLIHPQSVTHSIVRYVDGSYIAQLGVPDMKTPIANAMYYPKRGSVNVESLDFTKYQLTFREACFERFEALKIVFNNLQNKNYAANIVFNAANEELVAAFLNKKIKYLEIIEVNKKVTKELNFENPKNIEEVFEIDRKTREYVDSVLG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: NORV_ECOSM
Sequence: MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGIAETDPRVAVKIFNVARSDKNEILTNVFRSKGMLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREIARQWALAPLPQSTVNTVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGTPWSEVPDNFLCPECSLGKDVFDELASEAK
What is the function of this protein?
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes.  Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified.  NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center.  Also able to function as an aerobic oxygen reductase.
What are the official names of this protein?
Anaerobic nitric oxide reductase flavorubredoxin, FlRd, FlavoRb.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_PSEPG
Sequence: MHTLTLPAPAKLNLWLHIIGRRADGYHELETVFQFLDHGDELSFALREDGVIRLHTEIEAVPHDSNLIVRAARKLQEQSGTALGADIWLTKVLPMGGGIGGGSSDAATTLLALAHLWQLDWDEDRLAALGLSLGADVPVFVRGHAAFAQGVGEQLTPVDPIEPWYVVLVPQVSVSTVEIFSHPQLTRDSLPLKMRPVPEGNSRNDCQPVVEQNYPEVRNALNSLGKFTEARLTGTGSCVFGAFPSKAEADKVLALLSATQTGFVAKGSNISMLHRKLQSLVKKSSA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MYPT1_CHICK
Sequence: MKMADAKQKRNEQLKRWIGSETDLEPPVVKRKKTKVKFDDGAVFLAACSSGDTEEVLRLLERGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEYLISQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQARYDVNIKDYDGWTPLHAAAHWGKEEACRILVENLCDMEAVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKREKKSPLIESTANLDNNQTQKTFKNKETLIMEQEKNASSIESLEHEKADEEEEGKKDESSCSSEEEEDDDSESEAETDKAKTLANANTTSTQSASMTAPSVAGGQGTPTSPLKKFPTSTTKVSPKEEERKDESPASWRLGLRKTGSYGALAEITASKEAQKEKDSAGVIRSASSPRLSSSLDNKEKEKDGKGTRLAYVAPTIPRRLASTSDIDEKENRDSSASSIRSGSSYARRKWEEDVKKNSLNEGPTSLNTSYQRSGSFGRRQDDLVSSNVPSTASTVTSSAGLQKTLPASANTTTKSTTGSTSAGVQSSTSNRLWAEDSTEKEKDSVPTAVTVPVAPSVVNAAATTTAMTTATSGTVSSTSEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETKDDDYRQRYSRTVEEPYHRYRPTSTSTSTSSTSSLSTSTSSLSSSSQLNRPNSLIGITSAYSRSGTKESEREGGKKEEEKEEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEHQSDSEEGTNKKETQSDSLSRYDTGSLSVSSGDRYDSAQGRSGSQSYLEDRKPYCSRLEKEDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKTTQRQERFADRSLLEMEKRVSGKSQYLLGGKKSSRKKDI
What is the function of this protein?
Regulates myosin phosphatase activity.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 12A, 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase, Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, PP1M subunit M110, Protein phosphatase myosin-binding subunit.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, stress fiber. Note=Also along actomyosin filaments.
Protein: ZWILC_HUMAN
Sequence: MWERLNCAAEDFYSRLLQKFNEEKKGIRKDPFLYEADVQVQLISKGQPNPLKNILNENDIVFIVEKVPLEKEETSHIEELQSEETAISDFSTGENVGPLALPVGKARQLIGLYTMAHNPNMTHLKINLPVTALPPLWVRCDSSDPEGTCWLGAELITTNNSITGIVLYVVSCKADKNYSVNLENLKNLHKKRHHLSTVTSKGFAQYELFKSSALDDTITASQTAIALDISWSPVDEILQIPPLSSTATLNIKVESGEPRGPLNHLYRELKFLLVLADGLRTGVTEWLEPLEAKSAVELVQEFLNDLNKLDGFGDSTKKDTEVETLKHDTAAVDRSVKRLFKVRSDLDFAEQLWCKMSSSVISYQDLVKCFTLIIQSLQRGDIQPWLHSGSNSLLSKLIHQSYHGTMDTVSLSGTIPVQMLLEIGLDKLKKDYISFFIGQELASLNHLEYFIAPSVDIQEQVYRVQKLHHILEILVSCMPFIKSQHELLFSLTQICIKYYKQNPLDEQHIFQLPVRPTAVKNLYQSEKPQKWRVEIYSGQKKIKTVWQLSDSSPIDHLNFHKPDFSELTLNGSLEERIFFTNMVTCSQVHFK
What is the function of this protein?
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.  Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores.  Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131).
What are the official names of this protein?
Protein zwilch homolog, hZwilch.
What is the protein family that this protein belongs to?
Belongs to the ZWILCH family.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore.
Protein: KDUI_SALCH
Sequence: MDVRQSIHSEHAKTLDTQALRREFLIENIFVADEYTMFYSHIDRIIVGGIMPVSHSVEIGGEVGKQLGVSRLLDRRELGVINIGGAGAIIVDGQRHDIGHRDALYIGKGAKELVFVSNEASRPAKFYYNCAPAHTAYPTKKVSPADVAPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYLYFNMEEDSCVFHMMGQPQETRHIVMRNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVQDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: ISFD_KLEOX
Sequence: MATSKVVFITGATSGFGEAAAQVFADAGWSLVLSGRRFERLKTLQDKLASQVPVHIIELDVRDSDSVAAAVAALPADFADITTLINNAGLALSPQPAQKVDLDDWKTMIDTNVTGLVNVTHALLPTLINHGAGASIINIGSIAGQWPYPGSHVYGASKAFVKQFSYNLRCDLLGTGVRVTDLAPGIAETEFTLVRTKGDQAASDNLYRGTTPLSARDIAEQMFYIATLPDHMNINRVEVMPVRQAWQPFAIDRD
What is the function of this protein?
Catalyzes the formation of isethionate from 2-sulfoacetaldehyde in the deaminative pathway of taurine.  The enzyme is specific for NADPH; NADH is not a substrate.
What are the official names of this protein?
Sulfoacetaldehyde reductase, Isethionate formation reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MNMG_POLSJ
Sequence: MQSPYIYPQEFDVIVVGGGHAGTEAALASARMGCKTLLLSHNIETLGQMSCNPSIGGIGKGHLVKEVDAMGGAMALATDEGGIQFRILNSSKGPAVRATRAQADRILYKAAIRRRLENQPNLWLFQQAVDDLMVEGDRVVGAVTQVGIRFRSRTVVLTAGTFLDGKIHVGLNNYAAGRAGDPPAVSLSSRLKELKLPQGRLKTGTPPRIDGRTIDFSKCIEQPGDGMPGGTAGPVPVFSFMGGAIPHPQQMPCWITHTNERTHEIIRSGFDRSPMFTGKIDGVGPRYCPSVEDKINRFADKESHQIFLEPEGLTTHEIYPNGISTSLPFDIQYELVRSMAGMENAHILRPGYAIEYDYFDPRALKTTFETRAIGGLFFAGQINGTTGYEEAAAQGMFAGINAALQCRALGGLPNDHGGAWLPRRDEAYLGVLVDDLITKGVTEPYRMFTSRAEYRLMLREDNADMRLTEKGRELGLVDDARWDAFSRKRDAVSRETERLRSLWVNPHNLPLAEAERVLGKSIEREYNLLDLLRRPDVNYAGLMSLEEGKYANPELAAEAAASDDLAKSVIEQIEITAKYAGYIDLQKTEVERAAHYENLKLPTDLDYLQVSALSFEARQTLARHRPETLGMASRISGITPATVSLLLVHLKKNLWKNTVPLKTTDTSTEKAQA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_PSEP1
Sequence: MTDNNKYRDVEIRAPRGNKLTAKSWLTEAPLRMLMNNLDPQVAENPKELVVYGGIGRAARNWACYDKIVETLTRLEDDETLLVQSGKPVGVFKTHSNAPRVLIANSNLVPHWANWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYGGSLKGKWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLETRYVDEQATDLDDALARIAKYTAEGKAISIALHGNAAEILPELVKRGVRPDMVTDQTSAHDPLNGYLPAGWTWEQYRDRAQTEPAAVVKAAKQSMAVHVQAMLDFQKQGIPTFDYGNNIRQMAKEEGVANAFDFPGFVPAYIRPLFCRGVGPFRWAALSGEAEDIYKTDAKVKELIPDDAHLHRWLDMARERISFQGLPARICWVGLGLRAKLGLAFNEMVRSGELSAPVVIGRDHLDSGSVSSPNRETEAMRDGSDAVSDWPLLNALLNTAGGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAERIARVLTNDPGTGVMRHADAGYDIAIDCAKEQGLDLPMITG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHP_ECOLI
Sequence: MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFVGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAWRQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPANPAQKPGLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPASVRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
What is the function of this protein?
Could be involved in the export of 2,3-dihydroxypropane-1-sulfonate (DHPS).
What are the official names of this protein?
Putative 2,3-dihydroxypropane-1-sulfonate exporter.
What is the protein family that this protein belongs to?
Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLDA_GLUOX
Sequence: MRRSHLLATVACATLACAPLAANAQFAPAGSGGSPTSSVPGPGNGSGNSFEPTENTPAAKSRFSGPSPYAPQAPGVNAANLPDIGSMDPNDVPQMAPQQSASPASGDWAAYGHDDSQMRYSPLSEITPQNADQLKVAFVYHTGSYPRPGQTNKWAAETTPIKVGDGLYMCSAQNDIMKIDPATGKEIWRHNINEKYEAIPYTAACKGVTYFTSSQVPEGQPCHNRILEGTLDMRLIAVDAATGNLCEGFGNGGQVNLMQGLGESVPGFVSMTTPPPVVNGVVVVNHEVLDGQRRWAPSGVIRGYDAESGKFLWAWDVNRPNDHSQPTGNNHYSRGTPNSWAAMTGDNALGLVYVPTGNSASDYYSALRSPEENKVSSAVVALDVKTGSPRWVFQTVHKDVWDYDIGSQATLMDMPGQDGQPVPALIMPTKRGQTFVLDRRDGKPILPVEERPAPSPGVIPGDPRSPTQPWSTGMPALRVPDLKETDMWGMSPIDQLFCRIKFRRANYTGEFTPPSVDKPWIEYPGYNGGSDWGSVSYDPQSGILIANWNITPMYDQLVTRKKADELGLMPIDDPNYKPGGGGAEGNGAMDGTPYGIVVTPFWDQYTGMMCNRPPYGMITAIDMKHGQKVLWQHPLGTARANGPWGLPTGLPWEIGTPNNGGSVVTAGGVVFIAAATDNQIRAIDEHTGKVVWSAVLPGGGQANPMTYEANGHQYVAIMAGGHHFMMTPVSDQLVVYALPDHKG
What is the function of this protein?
Catalyzes the oxidation of glycerol to glycerone.  Also acts, more slowly, on a number of other polyols including D-sorbitol, D-arabinitol, D-mannitol, meso-erythritol, adonitol and propylene glycol (By similarity).
What are the official names of this protein?
Glycerol dehydrogenase large subunit, D-arabitol dehydrogenase large subunit, ARDH, D-sorbitol dehydrogenase subunit SldA, SLDH, Gluconate/polyol dehydrogenase large subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial PQQ dehydrogenase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MEND_SHIB3
Sequence: MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPSLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRISDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLQAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RS2_COLP3
Sequence: MSNVSMRDMLKAGVHFGHKTRYWNPKMKQFIFGARDKVHIINLEQTVPMFNEALAFVNNVSSKKGKVLFVGTKRAASDAIKDAAIKSDQFYVNHRWLGGMLTNWKTVRQSIKRLKDLESQSTDGTFEALTKKEALMRTREMEKLDKSLGGIKNMGGLPDVLFIIDADHEHIAIKEANNLGIPVISVVDTNSNPDGVDYVVPGNDDAIRAVTLYCDAVANSVLSGREQNIVVQAEKDGFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RNY_CALS8
Sequence: MQKISDTLKLIITAGVSIALAIVAFFLGYLYRKKIAEKTIKSAEQEAQRIVEEAKKQAEAYKKEATLLAKEEIHRARSEFDREVRERRAELQRFERRLIQKEEMLDKKMAAVEEKEEQLNQKIKDVQKLQEEIELLKQKQQEELQRISGLTQEEARQIILKSVEQDVKHDVALMIKELEQQAKEEADKKAREIIALAIQRYSSDYVAENTVSVVTLPNDEMKGRIIGREGRNIKTFETVTGIDLIIDDTPEAVILSGFDPIRREIAKLTLEKLILDGRIHPARIEEMYEKAKREVENKIREEGERVVFELGIHNLHPELIKLIGKLRYRTSYGQNVLAHSIEVANIAGIMAAELGLDQSIAKRAGLLHDIGKAVDHEVEGSHALIGYDLAKRYKETNPDVLEAIGGHHGEMETRSIYNVLIQAADSVSAARPGARRESLESYIKRLQKLEEIANSFDGVEKAYAIQAGREIRIMVKPDHVSDDDIVIMAREIVKRIESELDYPGQIKVNVIREVRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACLR_ACHOB
Sequence: MTKALYDRDGAAIGNLQKLRFFPLAISGGRGARLIEENGRELIDLSGAWGAASLGYGHPAIVAAVSAAAANPAGATILSASNAPAVTLAERLLASFPGEGTHKIWFGHSGSDANEAAYRAIVKATGRSGVIAFAGAYHGCTVGSMAFSGHSVQADAAKADGLILLPYPDPYRPYRNDPTGDAILTLLTEKLAAVPAGSIGAAFIEPIQSDGGLIVPPDGFLRKFADICRAHGILVVCDEVKVGLARSGRLHCFEHEGFVPDILVLGKGLGGGLPLSAVIAPAEILDCASAFAMQTLHGNPISAAAGLAVLETIDRDDLPAMAERKGRLLRDGLSELAKRHPLIGDIRGRGLACGMELVCDRQSREPARAETAKLIYRAYQLGLVVYYVGMNGNVLEFTPPLTITETDIHKALDLLDRAFSELSAVSNEEIAQFAGW
What is the function of this protein?
catalyzes the interconversion of L-alpha-amino-epsilon-caprolactam and D-alpha-amino-epsilon-caprolactam.
What are the official names of this protein?
2-aminohexano-6-lactam racemase, 2-amino-hexano-6-lactam racemase, Alpha-amino-epsilon-caprolactam racemase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: HS74L_RAT
Sequence: LSAMLEDTENWLYEELSLTQDPVV
What is the function of this protein?
Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase.
What are the official names of this protein?
Heat shock 70 kDa protein 4L, Heat shock 70-related protein APG-1, Osmotic stress protein 94.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=May translocate to the nucleus of germ cells after heat shock.