PharMolix/UniProtQA huggingface dataset:
Protein: YQCC_BACSU
Sequence: MAYDAKTDWLPDDPINEDDVNRWEKGIQDAHKDLAVHKNDMNNPHNTTKAQIGLGNVDNVQQASKKEFEEHRNDLQRHITPVERENWNAKETIVGAQEKADKALSDAKYYVDTNYKNNNLTLITGDNAIQDARTGGEEYPLGLTLMDIGQGNTTGYPLGYGIVKNEKYNNYRFTQYFYGTGNESGTYYDSTGVWIRHWWSGSGWTPWQKISGFAHANIGTTGVQYLKKIDHTKIAFNRVIKDSHNAFDTKNNRFIAPNDGMYLIGASIYTLNYTSYINFHLKVYLNGKAYKTLHHVRGDFQEKDNGMNLGLNGNATVPMNKGDYVEIWCYCNYGGDETLKRAVDDKNGVFNFFDIQELGGRNYPRF
What are the official names of this protein?
Uncharacterized protein YqcC.
What is the protein family that this protein belongs to?
To B.subtilis XkdV.
Protein: THES_BACSJ
Sequence: MKFKAIVSLSLAVSMSLFPFLVEAASNDGVESPKTVSEINVSHEKGAYVQGEVIVQFKEQVNAEEKAKALKEVGATAVPDNDRVKSKFNVLKVGNVEAVVKALNNNPLVEYAEPNYLFNAAWTPNDTYYQGYQYGPQNTYTDYAWDVTKGSSGQEIAVIDTGVDYTHPDLDGKVIKGYDFVDNDYDPMDLNNHGTHVAGIAAAETNNATGIAGMAPNTRILAVRALDRNGSGTLSDIADAIIYAADSGAEVINLSLGCDCHTTTLENAVNYAWNKGSVVVAAAGNNGSSTTFEPASYENVIAVGAVDQYDRLASFSNYGTWVDVVAPGVDIVSTITGNRYAYMSGTSMASPHVAGLAALLASQGRNNIEIRQAIEQTADKISGTGTYFKYGRINSYNAVTY
What are the official names of this protein?
Thermophilic serine proteinase, Ak.1 protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATB_DEHMC
Sequence: MTKYETVIGLEVHVQLDTKSKMFCRCSTDYASAEPNTHVCPVCLGMPGVLPTINKQAVEYTIMSGLALGCDIAPFTKFDRKNYAYPDLMKGYQISQYDQPLCGKGFLDINVDGVIRRIGITRIHLEEDVAKLHHESDINGQPYSLLDINRSSIPLMEVVSEPDMRTPEEARQYLMKLRTIMRYLGVSTANMEEGSFRCDANISIRPVGATELGAKVEVKNMNSFKAVFSALEYEEVRQRKMADEGKKISQETRGWQDEKCQTVSQRSKEFAHDYRYFPEPDLPPLHISCDWIEDIRAKLPELPETRKERFINGYWLSEYDASLLTASRELADYFEAVLGETDFQNIPQDKGVKEVANWVVGSVNSIMNTGGADITAFALKVSPASLCHLLVLVSAGKVNAATAKAVLEDMYATGQNAEAIIEKKGLSQISDSSELVAIAKKVLADNPKAVAEYNEGKTQVIGFLVGQMMKQSKGRANPNIAMELLKKALEEG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: IXTPA_ALIB4
Sequence: MKIVLASANKGKIKEFERLLPNDEIVAFSEILGKIEIDEDKDTFKGNAIKKAQTIYDELQKINFGDVVVISDDSGISVPVLGNAPGVYSARYAGLNASDKENNEKLKAELNKLGLEKTPAFYTACIAIVYKNEVYTVHGWMYGEVLNKEIGTNGFGYDPMFIPNGYDKTLGELDEGVKKEFSHRSKALKLAMKVLEVIL
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: RP22_MONPV
Sequence: MNQYNVKYLAKILCLKTEIARDPYAVINRNVLLRYTTDIEYNDLVTLITVRHKIDSMKTVFQVFNESSINYTPVDDDYGEPIIITSYLQKGHNKFPVNFLYIDVVISDLFPSFVRLDTTETNIVNSVLQTGDGKKTLRLPKMLETEIVVKILYRPNIPLKIVRFFRNNMVTGVEIADRSVISVAD
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG133, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 22 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 22 kDa subunit family.
Protein: MMAA2_MYCTU
Sequence: MVNDLTPHFEDVQAHYDLSDDFFRLFLDPTQTYSCAHFEREDMTLEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRRAIAQYDVNVVGLTLSKNQAAHVQKSFDEMDTPRDRRVLLAGWEQFNEPVDRIVSIGAFEHFGHDRHADFFARAHKILPPDGVLLLHTITGLTRQQMVDHGLPLTLWLARFLKFIATEIFPGGQPPTIEMVEEQSAKTGFTLTRRQSLQPHYARTLDLWAEALQEHKSEAIAIQSEEVYERYMKYLTGCAKLFRVGYIDVNQFTLAK
What is the function of this protein?
Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.  MmaA2 also catalyzes the biosynthesis of the cis-cyclopropanated methoxymycolates.  Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence.
What are the official names of this protein?
Cyclopropane mycolic acid synthase MmaA2, CMAS, Cyclopropane-fatty-acyl-phospholipid synthase, CFA synthase, Mycolic acid methyltransferase, MA-MT, S-adenosylmethionine-dependent methyltransferase, AdoMet-MT, SAM-MT.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
Protein: SBTXB_SOYBN
Sequence: PNPKVFFDMTIGGQSAGRIVMEEYA
What is the function of this protein?
Involved in plant defense (PubMed:18328522).  Inhibits spore germination in C. sojina, A. niger (at concentrations >50 ug/ml) and P. herguei but not in F. oxysporum and F. solani (PubMed:20831249, PubMed:18328522).  Does not inhibit vegetative mycelial growth (PubMed:20831249).  Inhibits growth of C. albicans and K. marxiannus but not P. membranifaciens or C. parapsilosis (PubMed:20831249, PubMed:23894655).  Probably acts by affecting the cell membrane (PubMed:20831249).  Does not have urease, chitinase, beta-1,3-glucanase or hemagglutination activities (PubMed:18328522, PubMed:20831249).  Does not inhibit trypsin (PubMed:18328522).  Injection into mice produces toxic effects such as dyspnea, tonic-clonic convulsion and death (PubMed:18328522).
What are the official names of this protein?
Soybean toxin 17 kDa chain, SBTX 17 kDa chain, Cyclophilin-like protein.
Protein: KHNYN_MOUSE
Sequence: MSTWGFASPTPDRFAVSAEAEDKVREQQTRLERIFNVGMSVLSKDCPENPHIWLQLEGPKENVCRAKEYLKGLCSPELQSEIHYPPRLHCIFLGAHGFFLDCLAWSTSAHLVPLLPGSLMISGLTEAFVMAQSRVEELVQRLSWDLQLQSCPGAPDNGGVLRDFSALLQTREDAYTEALLRLPLAVQEELLSLVQEASRGQGPSREVGSSGLLSPQFQGVRAPLNEGREFVGTRVAGSGKSPAVRGQSHTVEKEERKQDAVRDMGSGRKELSGEEVWEPGVAYRSQLAGGGAEEVAPLKGKASGKQEVPQQRGGFSVQGEPSGAHVPCQRAAPIRGASLLQRLHNGSASPPRVPSPPPAPEPPWPCGDRDRDRDRGDRGDKQQAGARGRGSPWKRGTRGGNLVTGTQRFQEALQDPFTLCLANVPGQPDLRHIVIDGSNVAMVHGLQHYFSSRGIALAVQYFWDRGHRDITVFVPQWRFSKDSKVRESHFLQKLYSLSLLSLTPSRVMDGKRISSYDDRFMVKLAEETDGIIVSNDQFRDLAEESDKWMAIIRERLLPFTFVGNLFMVPDDPLGRNGPTLDEFLKKPVRKQGSSKTQQPSKGSTEQANQQQGKDADRSNGGIRKTRETERLRRQLLEVFWGQDHKVDFILQREPYCRDINQLSEALLSLNF
What are the official names of this protein?
Protein KHNYN, KH and NYN domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the N4BP1 family.
Protein: CYV1_VIOOD
Sequence: GVFCGEACAQASCSIAGCECIAGLCYKN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide vodo I1.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: PG065_VAR67
Sequence: MSKIYIDERSDAEIVCEAIKNIGLEGVTAVQLTRQLNMEKREVNKALYDLQRSAMVYSSDDIPPRWFMTTEADKPDAMTMADVIIDDVSREKSMREDHKSFDDVIPAKKIIDWKNANPVTIINEYCQITKRDWSFRIESVGPSNSPTFYACVDIDGRVFDKADGKSKRDAKNNAAKLAVDKLLGYVIIRF
What is the function of this protein?
RNA-binding protein that plays a role in the inhibition of multiple cellular antiviral responses activated by double-stranded RNA (dsRNA), such as inhibition of PKR activation, necroptosis, and IFN-mediated antiviral activities.  Recognizes and binds Z-RNA structures via its Z-binding domain and dsRNA via its DRBM domain: RNA-binding activity is required to escape host ZBP1-dependent necroptosis.  Mechanistically, the Z-binding domain binds Z-RNAs that are produced during vaccinia virus infection, thereby competing with Z-RNA detection by host ZBP1, suppressing ZBP1-dependent necroptosis.  Acts as a key inhibitor of the interferon response by blocking the phosphorylation and subsequent activation of IRF3 and IRF7 kinases that are required for interferon-alpha gene expression.  Inhibits NF-kappa-B activation and the ubiquitin-like protein ISG15, which is an early antiviral protein.  The binding with host ISG15 subsequently blocks host ISGylation.
What are the official names of this protein?
RNA-binding protein OPG065, Protein E3.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG065 family.
Protein: SAHH_PSEFS
Sequence: MSAVNTPADFNDYKVADMSLAAWGRRETFIAESEMPALMGLRRKYAAEQPLKGAKILGCIHMTIQTAVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCLEQTILKDGAPWDANMILDDGGDLTELLHKKYPAILDRVHGVTEETTTGVHRLLDMLAKGELKIPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSSQSLRQEGMIVKVSEVDPICAMQACMDGFEVVSPFIDGVNDGTEASIDKALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKVHRTGAGAFDAQNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIFLFGQKYADLSPAQKAERLTVEVLPKKLDEEVALEMVRGFGGVVTQLTKTQADYIGVTVEGPFKPHAYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_MYCLE
Sequence: MQAGRQLFLVDCWLGVLQRASAGPTHTPAVCQRCCSTHLHGDRISDLGDLLITHWVTTFALDPPPLPIIGSPDTAETVEAKLKASGHDIEYQITHHTYLNTPPLIEVYEYTKGFVGAPPDGVSIRGSTNHGPVTPTIGFRIESGPTSVVLTGGTVPCASLDELAAEADALVHTIIRKNIVIRVHQQADQGHLQPPLVNRASDSNRGARGHRHPGHNVLCP
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity).
What are the official names of this protein?
Putative ribonuclease Z, RNase Z, tRNase Z, tRNA 3 endonuclease.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RLP1_ARATH
Sequence: MRTDERRRWWVKPKKHITLVFITITMIIQFQMKGCVSCVETERMGLLQLKSYLKNLVDAEEEEEEGLSILKSWTHHEGDCCRWERVKCSDAINGHVIGLSLDRLVPVAFESQTRSLNLSLLHSFPQLQSLNLSWNWFTNLSDHFLGFKSFGTLDKLTTLDFSHNMFDNSIVPFLNAATSIRSLHLESNYMEGVFPPQELSNMTNLRVLNLKDNSFSFLSSQGLTDFRDLEVLDLSFNGVNDSEASHSLSTAKLKTLDLNFNPLSDFSQLKGLESLQELQVLKLRGNKFNHTLSTHVLKDLKMLQELDLSDNGFTNLDHGRGLEIPTSLQVLDFKRNQLSLTHEGYLGICRLMKLRELDLSSNALTSLPYCLGNLTHLRTLDLSNNQLNGNLSSFVSGLPSVLEYLSLLDNNFDGSFLFNSLVNQTRLTVFKLSSKVGVIQVQTESSWAPLFQLKMLYLSNCSLGSTMLGFLVHQRDLCFVDLSHNKLTGTFPTWLVKNNTRLQTILLSGNSLTKLQLPILVHGLQVLDISSNMIYDSIQEDIGMVFPNLRFMNFSSNHFQGTIPSSIGEMKSLQVLDMSSNGLYGQLPIMFLSGCYSLRVLKLSNNQLQGKIFSKHANLTGLVGLFLDGNNFTGSLEEGLLKSKNLTLLDISDNRFSGMLPLWIGRISRLSYLYMSGNQLKGPFPFLRQSPWVEVMDISHNSFSGSIPRNVNFPSLRELRLQNNEFTGLVPGNLFKAAGLEVLDLRNNNFSGKILNTIDQTSKLRILLLRNNSFQTYIPGKICQLSEVGLLDLSHNQFRGPIPSCFSKMSFGAEQNDRTMSLVADFDFSYITFLPHCQYGSHLNLDDGVRNGYQPKPATVVDFLTKSRYEAYQGDILRYMHGLDLSSNELSGEIPIEIGDLQNIRSLNLSSNRLTGSIPDSISKLKGLESLDLSNNKLDGSIPPALADLNSLGYLNISYNNLSGEIPFKGHLVTFDERSYIGNAHLCGLPTNKNCISQRVPEPPSVSTHAKEEENEEEGNVIDMVWFYWTCAAVYISTSLALFAFLYIDSRWSREWFYRVDLCVHHILQFKRSSVCN
What is the function of this protein?
Involved in plant defense.  Confers resistance to the bacterial pathogen Xanthomonas through recognition of the microbe-associated molecular pattern (MAMP) eMax (PubMed:23898033, PubMed:24384530).  Functionality seems to depend on the presence of the receptor kinase SOBIR1 as an adapter protein (PubMed:24384530).
What are the official names of this protein?
Receptor-like protein 1, AtRLP1, Receptor of eMax.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SRD32_CAEEL
Sequence: MFVDIYDQLYISYAAVVSTLGIIFNGFLLFLIFFKSPSCLTPYTVFLANTSITQLGYCICFLLTVPRVISINLRIVNIYLGFSQFLGHWWSYMIFTTMLHFAVNSFLSIMLSMVFRCISLKTLRFPTSGAFAMCILAYMIPLSMVVSIRGIEITSNFTINSKYTLWQLENLDKYRTVVGTTMAQLSTLWVACCVSILCIPIYSVMFWCRYRILRMLERPGYMFNTTTTLQIKRLVKALTVQSLIPVFTLFPASLIFLSTQFHVIETTKFGYIIISLLSLSPTIDPLVTIYYVQPYRKYIVDLLWSEERPMVSPFLSNNDPRFYRSRSNSVLMMRNTHFV
What are the official names of this protein?
Serpentine receptor class delta-32, Protein srd-32.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srd family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPB_GLAP5
Sequence: MATGKIVQIIGAVIDVEFPQDAVPKVYDALKVETGLTLEVQQQLGGGVVRCIALGTSDGLKRGLKVENTNKAIEVPVGTKTLGRIMNVLGEPIDEAGPIGEEERWTIHRAAPSYEEQANSTELLETGIKVIDLIAPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDSTVVLSRNIASLGIYPAIDPLDSTSRQLDPLVVGQEHYDVARGVQKTLQRYKELKDIIAILGMDELSEDDKLVVARARKIERFLSQPFHVAEVFNSVPGKFVPLKETIRGFKGILAGEYDHIPEQAFYMAGSIDEVVERANKM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CCA_STAS1
Sequence: MTNSLFETAKPILEKLQAHHFQAYFVGGSVRDYLMNRPIHDIDITTSATPDEIETVFDKTIPIGREHGTINVIYKGEQYEVTTFRSEGDYDDHRRPNEVFFVRNLYDDVQRRDFTMNAIAMDINYQIFDYFEGQQDIKHQLIRTVGNPDERFDEDALRIIRGLRFQSQFGFHLEEATFTAMLNHIADIKYLAIERIVVELKKLTNGDFVSKSFNNLKHFMAFKYIPFFKHYDITKFTLRNAMPFTTFVAFLISQQREIDANIADLKVSNNEKKRIKTLVQLIDQIDEVQTKSQLKLFVYDYGKKDILEVLSYLDELKRNRITSISPLIVNDQTVTEVAKQLPMLSRSEMDINGKDILEIANKKSGPWLKETLREVEYAIISGEVVNFKPELKKWVKTRV
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: KCY_METHJ
Sequence: MRITISGLPGSGTTSLTYHLAEMHRLDVISAGEVFRQMARERGLTLAEFGSFCEEDPSVDKLIDERQREIALSNTHIIAEGRLSGWMIQEADLKIWLKASLECRVRRIFDRDQFSDLTAAMQATKEREACEALRYQQYYDIDIGSLSPYHLVLDTEMWTVEQLAIIVSSAIQTLQKSE
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP1_BURP0
Sequence: MSLWFLVFLSVLQGVTELFPVSSLGHTLLVPALFGMHIDKHAPQLLPFLVALHLGTALALLWYFRERWIALIAGFFASLNGRKNDEGHLMWALIIGTIPTGLVGLLLEKRIERVFHDLRIVAAALIINGVLLWLGDRIQRARAHRPPEKLTFKQAFFVGLAQVGALIPGFSRSGLTMIAGNAAGLTADKAAEFSFLLGTPIIFAAGLLELPKLFHAPDQLADALLGGVLTAIAAYLSVRFLMRYFEGRGRLASFGLYCVLAGLFCLGWFMFHAQPV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 1, Bacitracin resistance protein 1, Undecaprenyl pyrophosphate phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PASK_MOUSE
Sequence: MEDRGPPVFAEDWKCLSESPPVQEGPAAQATFEPSKPLSIAHKHLSRKNGLSRLCQSRMALSEDRWSSYCLSSLAAQNICTSKLHCAAAPEYADPTAGPLGSTSCCSLLRGLASGCSGSLLSTPVCNPNKAVFTVDAKTTEILVANDKACSLLGYSSHDLIGQKLAQFFLKSDSEVVEALSEEHVEADGHAAVVFGTVVDIVSRIGEKIPVSVWIKRLQQDRGLCCVVVLEPVERVSAWVAFQSDGTITSCDSLFAHLHGFTSPKDVVGQCVIDLIPSMQLPPPGQHIPKSLKIQRSVGRARDGTTFPLSLKLKSKPSGRAVADSEAASEPGYQASVWVFCTISGLITLLPDGTIYGVNHSFALMLFGYGKTELLGKNITFLIPGFYHYMDLTYDSSVQLPDLVNCLDIGRKSGPGEMNSDAQHNWELASGAQGPRIDVVLARDHMPSQDETLKLVGGQVSSRTQTRLETGYKILPSSACQPSLGVDSNPEDGEQSLLTDQQSIPKRNLPAHGGQNQLDTSEISLPVLKEHLLSEIQKNISEESPLTHRKWLSKVQQNPTKGSLPIHEEQLLFAGQHIHVLGKEDPSAAESYRESLLEESKSKPVDAKLFASCEDSEPLVSVKDRGSSVDTCNLHQEAQLELMGVSSPNPWADATMPEPHTTGQIAGGSLTYCPQYRSEWASQQRGQDSAPSPSGMACVLLGTPTLDEPWPGVRNDREELQTCLIKEQLSKSSCEGNLGISRVELVPEEHPPFTAPVSFCDLGGRDLHASRSGSSSACYALATDLPGVLEAVEAQEADVNSYSWNLKELFLKDQTDRTPSHCSCTTSELSEAPSLSVVGSDLDVGILHRQTSDILVDREMLLLTGTYFDLSEGQRFQEMGAGHDRAELSNISLVSSEHYETSDIESPGCDPPLPDPGPNDMCLSAEKPRPSAQITSTPVARGATSLQQEIQEGIYSGSCYHRDGLQLSIQFEVKRVELQGSATLFCCWLVKDLFHSHRDSATRTRLFLASLPSSTHSMPELSGSSFGEVLRAKPWFEESPTPAELEGLAACEGEYDYKYNTISPLGSGAFGFVWTAVEKECNKEVVVKFIKKEKVLEDCWIEDPKLGRVTLEIAILSKVDHANIIKVLDIFENQEFFQLVMEKHGSGMDLFAFIDHHPCLDEPLASFIFRQLVSAVGYLHSQGIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLIGNPYRGPELEMWSLGVTLYTLIFEENPFCEVEETMEAVIHPPFLVSQELMSLLSGLLQPCPEQRTTLEKLIRDPWVTQPVNLASYTWEEVCRTNQPESGLLSAASLEIGSRSPSEMAQREGLCGPPAPRETRGDQHCLHLKDPSLPVS
What is the function of this protein?
Serine/threonine-protein kinase involved in energy homeostasis and protein translation.  Phosphorylates EEF1A1, GYS1, PDX1 and RPS6.  Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions.  Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation.  May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences.  May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency.  May also participate in respiratory regulation.
What are the official names of this protein?
PAS domain-containing serine/threonine-protein kinase, PAS-kinase, PASKIN.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in the nucleus of testis germ cells and in the midpiece of sperm tails.
Protein: ASTE_DROME
Sequence: MGVRGLTSYIAQRAEIYLKPHELHSTALVIDGDNLSCNLYKDVTGSYSAFGGDYDDFYRAVVQFFQVLAECNIRPYVLMDGGYEERKLRTVSTRLRNKISVIKKINPNASITLFPLHLKEVFVDAVRDCGVPVMRCVFEADDELAALARKLNCPVLSYDSDFYIHNVKYIPLITLTVKVLTKQVKDKNSSNQKDSRDLRHCEAKNVKKRTRANKIVTGIQTTGLTASTKGSSKTYKYLDCCIYRVSHLCGRGTLSPEKLPLFAALLGNDYIARSAFKNFFAAGMGKAGRSRKLKLQQKRIQVILTWLKEETAESALAKVLSRLKKNQRDSLVSQVNAAISGYSNELCHAYDYFDEHYENAFPYIEPVSEEECSDDEHSSSSDEKFSDVEEGEDQEEADNQDEEQQEENQDVDSGDEEEEEADEGLELEVEDKTLLFPQWFLDKLYPAHLPRSFVDLMHLRKYINNPQIEHFPFHDSNEVALPILNYVFALLHHVECEKIELPLEVDMDIEGSTVPYLTYLTRALRVTNVRYFKMPIEKKPAYPFDPLSPDARHLRAVFEDNAPNADTEKLFSKLDQLPEDLRLYFLAIIYWLHRSEHCDLLHLHSLILSLVVLRTIDVTIPAEREVKTFLKRFGKTLKAERAVRDKEAAEGIKRGIKPALLELSVPDRMAHVPKSDCYLTQERLLPHFHMQEIFKKKFDLYSTTVIHAFAEFQAVVYQLNGLNSLLDFPLLSPRMNQLYCGAFLYNMYDVLRNRADVRYHVENFLLPDSKLMFDFYCYLYDWCAEFIPTWKRLEVDPTAAKALQKKRLKKQRQAARKVELREAIADPNAEMVEDADPENDFFDLNNKFCALKVA
What is the function of this protein?
May function in EGF receptor signaling.  May play a role in compound eye morphogenesis.
What are the official names of this protein?
Protein asteroid.
What is the protein family that this protein belongs to?
Belongs to the asteroid family.
Protein: NU3M_PATPE
Sequence: MIYTNNIFNFLTLFVSILIFLITTLITFAAHFLPSRNTDSEKSSPYECGFDPLNSARVPFSFRFFLVAILFLLFDLEIALLFPLPFSVFFHPIHTPLILTVGLIFEWVQGGLDWAE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CCG3_PONAB
Sequence: MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLKKSTFARLPPYRYRFRRRSSSRSTEPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAFLQFHNSTPKEFKESLHNNPANRRTTPV
What is the function of this protein?
Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization.  Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.  Thought to stabilize the calcium channel in an inactivated (closed) state.
What are the official names of this protein?
Voltage-dependent calcium channel gamma-3 subunit, Neuronal voltage-gated calcium channel gamma-3 subunit, Transmembrane AMPAR regulatory protein gamma-3, TARP gamma-3.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Displays a somatodendritic localization and is excluded from axons in neurons.
Protein: BACS1_HALSA
Sequence: MDAVATAYLGGAVALIVGVAFVWLLYRSLDGSPHQSALAPLAIIPVFAGLSYVGMAYDIGTVIVNGNQIVGLRYIDWLVTTPILVGYVGYAAGASRRSIIGVMVADALMIAVGAGAVVTDGTLKWALFGVSSIFHLSLFAYLYVIFPRVVPDVPEQIGLFNLLKNHIGLLWLAYPLVWLFGPAGIGEATAAGVALTYVFLDVLAKVPYVYFFYARRRVFMHSESPPAPEQATVEATAAD
What is the function of this protein?
Involved in the control of phototaxis.  Mediates both photoattractant (in the orange light) and photophobic (in the near UV light) responses.  The signal is then transmitted to the sensory rhodopsin I transducer (HTR-I) (By similarity).
What are the official names of this protein?
Sensory rhodopsin-1, Sensory rhodopsin I, SR-I.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPIA_FRATF
Sequence: MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKIKTVVSSSEDSTRKLKALGFDVVDLNYAGEIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFICIIDESKKVNTLGNFPLPIEVIPMARSYIARQIVKLGGQPVYREQTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIFALKPADTVIMATKDSNIVVL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.