PharMolix/UniProtQA huggingface dataset:
Protein: PIMT_PYRIL
Sequence: MALRLVEELTNEGIIKTERVKKAMLAVPREEFVMPEYRMMAYEDRPLPLFFDATISAPHMVAMMCELVEPRPGMKILEVGTGSGYQAAVCAEAIERKGKVYTIEIVKELAIYAAQNIERLGYWGIVEVYHGDGKKGLERHAPFDAIIVTAAARTIPSELIKQLKDGGVLVIPIEEGVGQVLYKITKRGEKIEKRAITYVLFVPLRDS
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_XANC8
Sequence: MSLVTSLTYVLPHRLLSSLARALAYSKSPATKQWLIDTVTRKFGVDLSEAQEPDPRVYPTFNAFFTRALKPGARVPDADPQALLMPADGRISQLGPIENGRIFQAKGQSFTAAELLGDESAAVPFHNGLFATVYLSPKDYHRVHMPWSGTLRETVHVPGRLFSVGPDAVRNVPRLFARNERLVCHFDTDFGPMASVMVGALLVSGVETVWSGVEIPRYGDRITRKDYRGKGITLERFAEMARFNYGSTVIVLLPPGVAALEGGLAAESSVRLGQALARRQVA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PRIB_SHEON
Sequence: MTTNNLVLSGTITRSRRFKSPAGIAHSVIMLEHKSQRYEADMLRNVYVQIQVILSGPRFESVADNLKAGVEVQVQGFMTLQQGRNGQNRLVIHAENVELKT
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: GASA7_ARATH
Sequence: MKIIVSILVLASLLLISSSLASATISDAFGSGAVAPAPQSKDGPALEKWCGQKCEGRCKEAGMKDRCLKYCGICCKDCQCVPSGTYGNKHECACYRDKLSSKGTPKCP
What is the function of this protein?
Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination, flowering and seed maturation.
What are the official names of this protein?
Gibberellin-regulated protein 7, GAST1 protein homolog 7.
What is the protein family that this protein belongs to?
Belongs to the GASA family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBB_CRYJA
Sequence: MGLPWYRVHTVVLNDPGRLIAVHIMHTALVSGWAGSMALYELAVFDPSDPILDPMWRQGMFVIPFMTRLGIKDSWGGWSITGETGSNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLDVFCDSRTGKPSLDLPKIFGIHLFLSGAACFGFGAFHVTGLYGPGIWVSDPYGLTGKIQPVNPAWGAEGFDPFVPGGIASHHIAAGILGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFIVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIDRRVRAGLAENLSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGAMDNGDGIAVGWLGHPIFKDKNGHELFVRRMPTFFETFPVVLVDEEGIVKADVPFRRAESKYSVEQVGVTVEFYGGELDGVSFGDPAIVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHATFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTKRQVV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: S1PR1_DANRE
Sequence: MDDLIARHYNFTGKFRKVHKDPGLKADSVVFIIVCCFIILENVLVLLTIWRTKKFHKPMYYFIGNLALSDLLAGVVYTANILLSGANTYKLTPTQWFFREGSMFVALAASVFSLLAIAIERHLTMLKMKLHNNGKTCRVFMLISTVWFIAAILGGLPVMGWNCIDSMNNCSTVLPLYHKAYILFCTTVFSVILMAIVILYARIYALVRTRSRKLVFRKVANGRGSNKSSEKSMALLKTVIIVLSCFIACWAPLFILLLLDVACQTLTCSILYKAEWFLALAVLNSAMNPLIYTLTSNEMRRAFIKMLNCGVCVQPSGKFSRPIMGAEFSRSKSDNSSHPNKDEPEYSPRETIVSSGNITSSS
What is the function of this protein?
G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins.  Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases.  Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1.  Required for normal chemotaxis toward sphingosine 1-phosphate.
What are the official names of this protein?
Sphingosine 1-phosphate receptor 1, S1P receptor 1, S1P1, Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL14_AQUAE
Sequence: MIQRQTYLNVADNSGAKKVQVIGIPYAPRKYATLGDVVTVTVKEALPQGNAKKGKIYRAIIVRTAKEVRRPDGSYIKFDDNACVLLNQYGEPLGTRVLGPIAREVRNKGFTKIASLAPEVV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SECAB_ARATH
Sequence: MTERIRARGPRSSSVNSVPLILDIEDFKGDFSFDALFGNLVNDLLPSFLDEEADSGDGHGNIAGVDGLTNGHLRGQSAPLSSAPFFPEVDGLLSLFKDACKELVDLRKQVDGRLNTLKKEVSTQDSKHRKTLTEIEKGVDGLFESFARLDGRISSVGQTAAKIGDHLQSADAQRETASQTIDLIKYLMEFNGSPGDLMELSALFSDDSRVAEAASIAQKLRSFAEEDIGRQGASTAAGNATPGRGLEVAVANLQDYCNELENRLLSRFDAASQRRDLSTMSECAKILSQFNRGTSAMQHYVATRPMFIDVEVMNSDIRLVLGDHGSQPSPSNVARGLSALFKEITDTVRKEAATITAVFPTPNEVMAILVQRVLEQRVTGILDKILAKPSLMSPPPVQEGGLLLYLRMLAVAYERTQELAKDLRAVGCGDLDVEDLTESLFSSHKDEYPEHERASLKQLYQAKMEELRAESQQVSESSGTIGRSKGASISSSLQQISVTFVTEFVRWNEEAITRCTLFSSQPATLAANVKAIFTCLLDQVSVYITEGLERARDSLSEAAALRERFVLGTSVSRRVAAAAASAAEAAAAAGESSFKSFMVAVQRCGSSVAIVQQYFANSISRLLLPVDGAHAASCEEMSTALSKAEAAAYKGLQQCIETVMAEVDRLLSSEQKSTDYRSPDDGIASDHRPTNACIRVVAYLSRVLESAFTALEGLNKQAFLTELGNRLEKLLLTHWQKFTFNPSGGLRLKRDLNEYVGFVKSFGAPSVDEKFELLGIIANVFIVAPDSLPTLFEGSPSIRKDAQRFIQLREDYKSAKLATKLSSLWPSLS
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion.  Involved in polarized cell growth and organ morphogenesis.  During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall.
What are the official names of this protein?
Exocyst complex component SEC10b, AtSec10b.
What is the protein family that this protein belongs to?
Belongs to the SEC10 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Secreted, extracellular exosome. Note=Shuttles from the cytoplasm to the exocyst-positive organelle (EXPO) in the presence of EXO70E2.
Protein: AAER_ECO57
Sequence: MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK
What is the function of this protein?
Activates transcription of the aaeXAB operon.
What are the official names of this protein?
HTH-type transcriptional activator AaeR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: BZP60_ARATH
Sequence: MAEEFGSIDLLGDEDFFFDFDPSIVIDSLPAEDFLQSSPDSWIGEIENQLMNDENHQEESFVELDQQSVSDFIADLLVDYPTSDSGSVDLAADKVLTVDSPAAADDSGKENSDLVVEKKSNDSGSEIHDDDDEEGDDDAVAKKRRRRVRNRDAAVRSRERKKEYVQDLEKKSKYLERECLRLGRMLECFVAENQSLRYCLQKGNGNNTTMMSKQESAVLLLESLLLGSLLWLLGVNFICLFPYMSHTKCCLLRPEPEKLVLNGLGSSSKPSYTGVSRRCKGSRPRMKYQILTLAA
What is the function of this protein?
Transcription factor involved in the unfolded protein response (UPR).  Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE).  Plays a role in plant immunity and abiotic stress responses.
What are the official names of this protein?
bZIP transcription factor 60, AtbZIP60.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Note=The bZIP domain is translocated into the nucleus in response to ER stress.
Protein: HIS81_HYDCU
Sequence: MSQYWSQLVHTLTPYVPGEQPKVDNLIKLNTNESPYPPSPLVLNALSSQLNDKLRLYPDPSSEDLKQSIATYYGVESNQVFVGNGSDEVLAHAFMTLLKQDKPILFPDISYSFYPVYCGLYEIEHQTIPLTDDFKINPADYNIENGGIIFPNPNAPTGRLLPLQAIEQIVQQNASSVVVVDEAYIDFGGESAAQLVLRYPNLLVVQTFSKSRALAGLRVGFAIGDKALIDGLERVKNSFNSYPLDRLATAGAIAAIEDEPYFQQSCEKIITTRDTLTHFLEDNGFEVIPSAANFVFTRHSEMRAEDIANQLREQAIIVRYFNKPRIDQYLRITIGTEEENTQLCRALTDILKTQNA
What are the official names of this protein?
Histidinol-phosphate aminotransferase 1, Imidazole acetol-phosphate transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RL7_SYNWW
Sequence: MSKVQEVIDIVKQMTVLELSELVKALEEEFGVSAAAPVAVAAAPAAGAVAEAVEEQYEFDVILTSSGEKKINVIKVVREITGLGLKEAKTLVDECPNPVKEKITKEEANEIKAKIEEAGGSVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SECD_METJA
Sequence: MDISKLLKDRKILILIIFVTLSVFLIVFKGLDFGIDLSGGTIIVLKAEKPMSDKEIEATIKIITERLNYNGLNDVVIYPRGNDEIIVEIPKSCDTDRIIKILKQQGVFVAKIDNITAYTGSDVQNVELPTKIPQGETWAYGVPFELTLEGAKKFAEVAKGKAYHKVELYMDGKLISAPVLSPDLADGKPHPQQVITVGAYPPTKEEIDEAMAIYSALKSGALPVKLDIEYISTISPEFGKEFLKGTAIALLLAFIAVGIIVSIRYKQPKIAIPILITCISEVIIILGFASLIDWKLDLPSIAGIIAAVGTGVDNQIVITDEALKRGAGKIRASIKRAFFIIFASAATSIAAMLPLFVLGVGMLKGFAITTIAGVLIGIFITRPAFARIIEEMFKKF
What is the function of this protein?
Involved in protein export.
What are the official names of this protein?
Protein-export membrane protein SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAA8B_RAT
Sequence: MTSNFSQATLQLCYENVNASCIKTPYSPGLRVLLYMVFGFGAVLAVCGNLLVVISVLHFKQLHSPANFLIASLASADFLVGISVMPFSMVRSIESCWYFGDTFCSLHSCCDAAFCYSSLFHLCFISVDRYIAVTEPLVYPTKFTMSVSGICISISWILPLVYSSAVFYTGISATGIENLVSALNCVGGCQVAINQDWVLISFLLFFIPTLVMIILYSKIFLVAKQQAVKIETSISGSKGESSLESHKARVAKRERKAAKTLGVTVMAFMVSWLPYTIDTLIDAFMGFITPAYVYEICGWIAYYNSAMNPLIYAFFYPWFRKAIKLILSGKILKGHSSTTSLFSE
What is the function of this protein?
Orphan receptor.  Could be a receptor for trace amines.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.
What are the official names of this protein?
Trace amine-associated receptor 8b, TaR-8b, Trace amine receptor 8b, Trace amine receptor 7, TaR-7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH602_MYCLE
Sequence: MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVKEGLRNVAAGANPLGLKRGIEKAVDKVTETLLKDAKEVETKEQIAATAAISAGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDAERQEAVLEEPYILLVSSKVSTVKDLLPLLEKVIQAGKSLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGAQVISEEVGLTLENTDLSLLGKARKVVMTKDETTIVEGAGDTDAIAGRVAQIRTEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVTLLQAAPALDKLKLTGDEATGANIVKVALEAPLKQIAFNSGMEPGVVAEKVRNLSVGHGLNAATGEYEDLLKAGVADPVKVTRSALQNAASIAGLFLTTEAVVADKPEKTAAPASDPTGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, 65 kDa antigen, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Secreted, capsule. Cell surface. Secreted, cell wall.
Protein: LYAM2_HUMAN
Sequence: MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESDGSYQKPSYIL
What is the function of this protein?
Cell-surface glycoprotein having a role in immunoadhesion.  Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1.  May have a role in capillary morphogenesis.
What are the official names of this protein?
E-selectin, CD62 antigen-like family member E, Endothelial leukocyte adhesion molecule 1, ELAM-1, Leukocyte-endothelial cell adhesion molecule 2, LECAM2.
What is the protein family that this protein belongs to?
Belongs to the selectin/LECAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: EFTS_RHIE6
Sequence: MSEITAAMVKELREKTGAGMMDCKKALAETNGDMEAAIDWLRAKGIAKADKKSGRTAAEGLIGVSSEGTKAVVVEVNSETDFVARNDAFQDLVRGIAKVAVSTNGSVEAVAAATYPASGKSVSDTIKDAIATIGENMNLRRSVALSVEDGVVATYIHNAVSDGLGKLGVLVALKSTGDKEALNAIGRQVAMHIAATAPLAIRPEEVDAAVAERERNVFIEQSRASGKPDNIIEKMVEGRMRKFFEEVALLSQAFVINPDLTVAAAVKEAEKAVGAPIEVAGMARLLLGEGVEKEETDFAAEVAAAVKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_STRPY
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTQATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KV6A5_MOUSE
Sequence: EIVLTQSPAITAASLGQKVTITCSASSSVSSLHWYQQKSGTSPKPWIYEISKLASGVPARFSGSGSGTSYSLTINTMEAEDAAIYYCQQWTYPLITFGAGTKLELKR
What are the official names of this protein?
Ig kappa chain V-VI region J539.
Protein: NCAP_CVPRM
Sequence: MANQGQRVSWGDESTKIRGRSNSRGRKINNIPLSFFNPITLQQGAKFWNSCPRDFVPKGIGNRDQQIGYWNRQTRYRMVKGQRKELPERWFFYYLGTGPHADAKFKDKLDGVVWVAKDGAMNKPTTLGSRGANNESKALKFDGKVPGEFQLEVNQSRDNSRSRSQSRSRSRNRSQSRGRQQSNNKKDDSVEQAVLAALKKLGVYTEKQQQRSRSKSKERSNSKTRDTTPKNENKHTWKRTAGKGDVTRFYGARSSSANFGDSDLVANGSSAKHYPQLAECVPSVSSILFGSYWTSKEDGDQIEVTFTHKYHLPKDHPKTEQFLQQINAYASPSELAKEQRKRKSRSKSAERSEQEVVPDSLIENYTDVFDDTQVEMIDEVTN
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the alphacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: PDXT_STRCO
Sequence: MSDTPVIGVLALQGDVREHLVALAVADAVARPVRRPEELAEVDGLVLPGGESTTISKLAVLFGVMDPLRARVRDGMPVYGTCAGMIMLADKILDPRSGQETVGGIDMIVRRNAFGRQNESFEAAVDVEGVEGEPVEGVFIRAPWVESVGAAAEVLAEHDGHIVAVRQGNALATSFHPELTGDHRVHRLFADMVRANRAAQSL
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: HPPK_STRP6
Sequence: MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETTAWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFGEEVYDTKELKVPHPYMTERAFVLIPLLELQSDLKLPPNHKFLRDYLAALDQSDITLFSAQQTEF
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: RS3_RICM5
Sequence: MGQKVCAHGFRVGPTLIKGWDSVLYAEKHYKTLFIQDLKIRDVINKGFNQAQISRVLIERPSNKSIIININAKKPNIIIGRNGSEIDKLKKAIEKMTSLKEVYINIHEVRKFNIDAAIVAQTIALQLEKRVSFRKAMKTAIQASFKQGGQGIRVSCSGRLGGAEIARTEWYIEGRMPLHTLRADIDYSTAEAITTYGVIGVKVWIYKGEYTENKRYN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: S47A2_PONAB
Sequence: MDSLQDTVPLDHGGCCPALSRLVPRGFGTEMWTLFALSGPLFLFQVLTFMIYIVSTVFCGHLGKVELASVTLAVAFVNVCGVSVGVGLSSACDTLMSQSFGSPNKKHVGVILQRGALVLLLCCLPCWALFLNTQHILLLFRQDPEVSRLTQDYVMIFIPGLPVIFLYNLLAKYLQNQKITWPQVLSGVVGNCVNGVANYALVSVLNLGVRGSAYANIISQFAQTVFLLLYIVLKKLHLETWAGWSSQCLQDWGPFFSLAVPSMLMICVEWWAYEIGSFLMGLLSVVDLSAQAVIYEVATVTYMRHSHHLAYTAHVARIPLGLSIGVCVRVGMALGAADTVQAKRSAVSGVLSIVGISLVLGTLISILKNQLGHIFTNDEDVIALVSQVLPVYSVFHVFEAICCVYGGVLRGTGKQAFGAAVNAITYYIIGLPLGILLTFVVRMRIMGLWLGMLACVFLATAAFVAYTARLDWKLAAEEAKKHSGQQQQQQRAESTATRSGPEKAVLSSVATGSSPGITLTTYSRSECHVDLFRTPEEAHTLSAPTSRLSVKQLVIRRGAALGAASATLMVGLTVRILATRH
What is the function of this protein?
Multidrug efflux pump that functions as a H(+)/organic cation antiporter.  Mediates the efflux of cationic compounds, such as the model cations, tetraethylammonium (TEA) and 1-methyl-4-phenylpyridinium (MPP+), the platinum-based drug oxaliplatin or weak bases that are positively charged at physiological pH, cimetidine or the antidiabetic drug metformin.  Mediates the efflux of the endogenous compounds creatinine, thiamine and estrone-3-sulfate.  Plays a physiological role in the excretion of drugs, toxins and endogenous metabolites through the kidney.
What are the official names of this protein?
Multidrug and toxin extrusion protein 2, MATE-2, Solute carrier family 47 member 2.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YICR_SALHS
Sequence: MDTLDELLPREKMLRSGIASLSDVELLALFLRTGTPGKDVMTLAKEILQHFGSLYGLLSADFAQFRGVNGIGLAKFAQLKGIAELARRYYSVRMNEESALLSPEMTREFLQSQLTGEEREIFLVIFLDAQHRVLQHSRLFSGTLNHVEVHPREIVREAIKLNASAVILAHNHPSGCAEPSKADKLITERVIKCCQFMDIRVLDHLIIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: MPKC_ASPNC
Sequence: MAEFLRSQILGTTFETTNRYSDLQPVGLGAFGLVCSAYDMITRQPVAIKKMMKPFSNATLAKRTYREVKLLKHLRHENLIGLSDIFISPLEDVYLVTDLLGTDLNRLLTSKPLDGKFVQYFTYQLLRGLKYIHSAGVIHRDLKPSNILINENCDLKICDFGLARLQEPQMTGYVSTRYYRAPEIMLTWQKYGMQVDIWSAGCIVAEMLRGKPLFPGKDHINQFFLITDALGNPPDEVIERICTKTTLDLVKSLPKRQPAPWATLFPDSDENAIDLLGEMLIFDPDKRISAAKALEHPYLSVYHDPTDEPVAEQMFDWSFSEVAHSIDEWKIMIYTEVVDFHDIGPTEEPVITEPFLSPDPSLSPEVLDPLGQIQTQSMVTKSAETLDQDILQYLQI
What is the function of this protein?
Mitogen-activated protein kinase required for growth on media where sorbitol or mannitol is the sole carbon source.
What are the official names of this protein?
Mitogen-activated protein kinase mpkC, MAP kinase C.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
Protein: SYS_SHESM
Sequence: MLDPKFLRNELAVTAERLATRGFILDVAHLTQLEEKRKSLQVATEELQASRNAISKSIGQAKARGEDVDAIMAQVGDLGAQLDAKKVELAAVLEEVNAIAMSMPNLPDESAPIGADETENVEIRRWGTPRSFDFPVKDHIDLGEGLNGLDFKSAVKITGSRFIVMKGQIARLNRALGQFMLDLHTTEHGYTEAYVPLLVNEASLLGTGQLPKFGEDLFHTKPATEEGQGLSLIPTAEVPLTNLVRDSIVDEDELPIKLTAHTACFRSEAGSYGKDTRGLIRQHQFDKVELVQLVKPEDSMAALEALTGHAETVLQRLGLPYRTVILCTGDMGFGSSKTYDIEVWLPGQNTYREISSCSNMKDFQARRMQARYRVKADNKPALLHTLNGSGLAVGRTLVAILENYQNADGSVTIPEALRPYMGGLTQIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.