PharMolix/UniProtQA huggingface dataset:
Protein: HAT1_CRYNB
Sequence: MAETLEEWISDSNQVLNLQMVRTPEDASLLQYEEQQNIDVFNPAFTYPIFGDNEKIFGYKGLDIKLHFASGSLRQYLDISYDAKLASSTTPPDEIEGALYKFIPPDYTKSEVEFQKRVAGDAETFKPLGEKIGSYAHPSAGRKGKGQGDSGMAAGKAIEDNEDVVEYEMYKATWSTPGFREYHRRMQIFVLLFIEGGSYVHEDEDAWEFIVLYERRTRPDSGIFTYHFVGYVSVYPFWCYPDRVRLRLSQFVILPPYQHQGHGSKLYNMLFRHMLDRSEVAELTIEDPAEAFEDLRDRNDLRFLVKEGIVKDPMLYVDVGKGKRGSRVEWELAIRRKYKIAQRQFDRLLEMLLFRQLDKGNPDKVKAYRLHVKARLYRFNYEMLSQMTVEERKEALAKTYESVVEDYKRILGMTFG
What is the function of this protein?
Catalytic component of the histone acetylase B (HAT-B) complex.  Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.  Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.  Involved in DNA double-strand break repair.
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NFIL_PIG
Sequence: MGSRLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKAEVKQKWASRLLAKLRKDIRPECREDFVLAITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERGEAGRARGRGSDGREGMRRASQSGRPGESGPAGLRDQAGTRSLGWAG
What is the function of this protein?
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2.  These proteins are individually capable of activating transcription and replication.
What are the official names of this protein?
Nuclear factor 1, CCAAT-box-binding transcription factor, CTF, Nuclear factor I, NF-I, TGGCA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the CTF/NF-I family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASTC_SALPC
Sequence: MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMHYGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNTINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQTGGASCG
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: DNAB_MYCTU
Sequence: MAVVDDLAPGMDSSPPSEDYGRQPPQDLAAEQSVLGGMLLSKDAIADVLERLRPGDFYRPAHQNVYDAILDLYGRGEPADAVTVAAELDRRGLLRRIGGAPYLHTLISTVPTAANAGYYASIVAEKALLRRLVEAGTRVVQYGYAGAEGADVAEVVDRAQAEIYDVADRRLSEDFVALEDLLQPTMDEIDAIASSGGLARGVATGFTELDEVTNGLHPGQMVIVAARPGVGKSTLGLDFMRSCSIRHRMASVIFSLEMSKSEIVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARRMSEISEAPLFIDDSPNLTMMEIRAKARRLRQKANLKLIVVDYLQLMTSGKKYESRQVEVSEFSRHLKLLAKELEVPVVAISQLNRGPEQRTDKKPMLADLRESGCLTASTRILRADTGAEVAFGELMRSGERPMVWSLDERLRMVARPMINVFPSGRKEVFRLRLASGREVEATGSHPFMKFEGWTPLAQLKVGDRIAAPRRVPEPIDTQRMPESELISLARMIGDGSCLKNQPIRYEPVDEANLAAVTVSAAHSDRAAIRDDYLAARVPSLRPARQRLPRGRCTPIAAWLAGLGLFTKRSHEKCVPEAVFRAPNDQVALFLRHLWSAGGSVRWDPTNGQGRVYYGSTSRRLIDDVAQLLLRVGIFSWITHAPKLGGHDSWRLHIHGAKDQVRFLRHVGVHGAEAVAAQEMLRQLKGPVRNPNLDSAPKKVWAQVRNRLSAKQMMDIQLHEPTMWKHSPSRSRPHRAEARIEDRAIHELARGDAYWDTVVEITSIGDQHVFDGTVSGTHNFVANGISLHNSLEQDADVVILLHRPDAFDRDDPRGGEADFILAKHRNGPTKTVTVAHQLHLSRFANMAR
What is the function of this protein?
The intein is an endonuclease.
What are the official names of this protein?
Replicative DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DnaB subfamily.
Protein: PDH1_PENVA
Sequence: MRSAVVVALLVMVAMSLQLTAAQEDLKYFEREVVAELAAQILRVAQGPSAFVAGPHKRNSELINSLLGIPKVMNDAGRR
What is the function of this protein?
The pigment-dispersing hormone causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas.  May also function as a neurotransmitter and/or neuromodulator (By similarity).
What are the official names of this protein?
Pigment-dispersing hormone type 1.
What is the protein family that this protein belongs to?
Belongs to the arthropod PDH family.
What are the subcellular locations of this protein?
Secreted.
Protein: NIRS_PSEAE
Sequence: MPFGKPLVGTLLASLTLLGLATAHAKDDMKAAEQYQGAASAVDPAHVVRTNGAPDMSESEFNEAKQIYFQRCAGCHGVLRKGATGKPLTPDITQQRGQQYLEALITYGTPLGMPNWGSSGELSKEQITLMAKYIQHTPPQPPEWGMPEMRESWKVLVKPEDRPKKQLNDLDLPNLFSVTLRDAGQIALVDGDSKKIVKVIDTGYAVHISRMSASGRYLLVIGRDARIDMIDLWAKEPTKVAEIKIGIEARSVESSKFKGYEDRYTIAGAYWPPQFAIMDGETLEPKQIVSTRGMTVDTQTYHPEPRVAAIIASHEHPEFIVNVKETGKVLLVNYKDIDNLTVTSIGAAPFLHDGGWDSSHRYFMTAANNSNKVAVIDSKDRRLSALVDVGKTPHPGRGANFVHPKYGPVWSTSHLGDGSISLIGTDPKNHPQYAWKKVAELQGQGGGSLFIKTHPKSSHLYVDTTFNPDARISQSVAVFDLKNLDAKYQVLPIAEWADLGEGAKRVVQPEYNKRGDEVWFSVWNGKNDSSALVVVDDKTLKLKAVVKDPRLITPTGKFNVYNTQHDVY
What are the official names of this protein?
Nitrite reductase, Cytochrome cd1, Cytochrome oxidase, Hydroxylamine reductase.
What are the subcellular locations of this protein?
Periplasm.
Protein: CLB_ARATH
Sequence: MGLISGILFGIIFGVALMAGWSRMMTHRSSKRVAKAVDMKLLGSLSRDDLKKICGDNFPQWISFPAFEQVKWLNKLLSKMWPYIAEAATMVIRDSVEPLLEDYRPPGITSLKFSKLTLGNVAPKIEGIRVQSFKEGQVTMDVDLRWGGDPNIVLGVTALVASIPIQLKDLQVFTVARVIFQLADEIPCISAVVVALLAEPKPRIDYTLKAVGGSLTAIPGLSDMIDDTVDTIVKDMLQWPHRIVVPIGGIPVDLSDLELKPQGKLIVTVVKATNLKNKELIGKSDPYATIYIRPVFKYKTKAIENNLNPVWDQTFELIAEDKETQSLTVEVFDKDVGQDERLGLVKLPLSSLEAGVTKELELNLLSSLDTLKVKDKKDRGSITLKVHYHEFNKEEQMAALEDEKKIMEERKRLKEAGVIGSTMDAVGMVGSGLGAGVGMVGTGIGTGVGLVGSGVSSGVGMVGSGFGAVGSGLSKAGRFMGRTITGQSSKRSGSSTPVNTVPENDGAKQQ
What is the function of this protein?
May be involved in membrane trafficking (By similarity).  Acts as a repressor of abiotic stress (e. g.  drought and salt) responses by binding specifically to the promoter of THAS1 to regulate its transcription (PubMed:21252258).  Binds to membrane lipid ceramides (PubMed:21252258).
What are the official names of this protein?
Calcium-dependent lipid-binding protein, AtCLB, CaLB protein, Protein NTMC 2 TYPE 4, NTMC2TYPE4.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein. Note=Localized in the nucleus membrane of root tips cells.
Protein: YME2_PHANO
Sequence: MRVEDHCSVFAWSSLQASRPWPAAGRYASLQAGEDKTGHISAGPNEGILFFNNVFPIQIRKIMGLPMPRILDRLISPAMSGTDPNTVIQRAKAKRNLPIESTEILPRVREGGAFVKFTHDGSTPTSEIEKTLQEYLRDEPVKPWWSPWKRMRAKVVKGRPWVEDMMRLPAPRLRVEFVPGEPGASVTEAVDLSQEQLFQFFRPYGKLSDIVMQESDSKVLPKFAYLDYSSIGKAIMAKNCMHGYLVSEAEGGGKKGTFLRLKYEQKIKPRYIRDWIINHPRIIIPIIAALIAGTVAIVFDPIRTFFVKAHITRTLHLEDNKWYKWIKGYASDIIRGHKRDEDDSYDAIWDDRKGNIEQIQTWLMETADTFIIVQGPRGSGKKELVVDQALQDNKLKLVIDCKPIQEARGDSPTISAAAAAVGYKPVFSWMNSISGMIDMAAQGATGMKTGFSETQETQLNKIWNTTTTALKQIALERRHKDDRDANLADDDWLEAHPEHRPVVVIDNFLHKSHEGGIVYDKMAEWAARLTTTNIAHVIFLTNDVAFSKSLSKALPDRVFRQISLSDCSPDVAKKFVVTHLDADVEDDPAPKDGSEKKLPSQHRTDLAELDSCIDLLGGRLTDLEFLARRIKTGETPNKAVNEIIDQSASEILKMYIFGAEDDGGRRKWSPEQAWMLIKELAQKESLRYNEVLLDDILKTGGESALRDLEQAELISIISGPNGRPSTIRPGKPVYHSAFKRLAQDKVLKSHLDYAILTNLTKIENATIDKCENELLLLSKLRNQPAQTAGRVQYLLAKLSASQVKVEKYETEIKGLKKVMAEED
What is the function of this protein?
Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape.  Involved in the regulation of mtDNA nucleotide structure and number.  May have a dispensable role in early maturation of pre-rRNA (By similarity).
What are the official names of this protein?
Mitochondrial escape protein 2.
What is the protein family that this protein belongs to?
Belongs to the YME2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ISPD_NITEC
Sequence: MVKFIALITAAGSGSRMGEDIPKQYRPLAGKPMIYHALRTLCGIARISTVCIVLAPEDTEWIRHNWREFAGKIQIFNCGGATRAESVTNGLKALRAANHVQDQDWILVHDAARPGLSTTLVERLLDQLADDEVGGLLAVPLADTLKRADDAGRVICTEPRERLWQAQTPQMFRMKLLLEALEKAPAGITDDASAVEALGLSPKLVVGNAYNFKVTYPQDLKLAELILRERAIT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PYRG_SHIB3
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: LCN12_MOUSE
Sequence: MGPWWALWLILTLPQILESQISAMSQGFPQMTSFQSDQFQGEWFVLGLADNTFRREHRALLNFFTTLFELKEKSQFQVTNSMTRGKHCNTWSYTLIPATKPGQFTRDNRGSGPGADRENIQVIETDYITFALVLSLRQTSSQNITRVSLLGRNWRLSHKTIDKFICLTRTQNLTKDNFLFPDLSDWLPDPQVC
What is the function of this protein?
Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis.  May play a role in male fertility (By similarity).
What are the official names of this protein?
Epididymal-specific lipocalin-12.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AXE1_ASPFN
Sequence: MILLSYLLTYLLCALTCSARAIHNGRSLIPRAGSLEQVTDFGDNPSNVKMYIYVPTNLASNPGIIVAIHYCTGTAQAYYQGSPYAQLAETHGFIVIYPESPYEGTCWDVSSQATLTHNGGGNSNSIANMVTWTTKQYNADSSKVFVTGTSSGAMMTNVMAATYPDLFAAGIAYAGVPAGCFLSTADQPDAWNSTCAQGQSITTPEHWASIAEAMYPDYSGSRPKMQIYHGNVDTTLYPQNYEETCKQWAGVFGYNYDAPESTESNTPEANWSRTTWGPNLQGILAGGVGHNIQIHGDEDMKWFGFTN
What is the function of this protein?
Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone (By similarity).
What are the official names of this protein?
Probable acetylxylan esterase A.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 1 (CE1) family. AxeA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IF2_FRATF
Sequence: MAEITVGQLAQQTNKEVDALLKQLKSFGIEKSSEKDTLTPTEMKTLLEKINSAKNTATRKKVTSVKLDGKHKINVSVKRKRRVAKKMEQQESTTLEQPQELETMVQEVSQQVDIVKEQDNIEQIVENKEAVKVQEQRQAEIAKPVIKDSGFKITAMPEIKIEEIVAEDDEGLAASDKQAKKKAAKKVFSEAVNTNTKYKCEEEEKKSKAKKAGGKGFKKANPRQLSQLAGDLESFDEFGAKKGKLKAPKVKKQEFTKPVENTVRTVEIHEGITVSELAQKMAVKGAEIVKVLFNMGVMATINQSLDQDTAILIVEEMGHKYTLHNENALEEAVTIVDRSSYKKISRAPVVTIMGHVDHGKTSLLDYIRQTRVVAGEAGGITQHIGAYSVKTDKGSITFLDTPGHEAFTSMRARGAKSTDIVILVVAADDGVMPQTEEAIQHAKAARVPIVVAVNKIDKPEADSDKVISELAQRNVIPESWGGDVMFVNVSAKTGEGVADLLEAVLLQSEVLELEAFAEGLAEGVVIESRLEKGRGPVATVLVQNGNLKQGDNILCGTEYGRVRAMHNDLGKKIKAAGPATPVEILGLSGVPAAGDEMVVIENEKKAKELAAQRSQKQKEAKIAQEQSLKLSNMFNNMGKEGEQQVLKIILKGDVQGSVEAIRESLLKLSTDEVKVDIIASGIGAITSSDVTLAVASTAVVIGFNVRADSAAKKLAETDGVEFRYYNIIYDLIDDVKKAMSGLLSPEMKEQIIGIAEVREVYRSSKFGSIAGCMVIEGVVKRTNPIRVLRNNVVIYEGTLESLKRFKDDASEVKKGLECGIGVKNYNDVREGDQIEVFEVIEVAKEL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXAC_BACFR
Sequence: MKNFMDKNFLLQTETAQELYHNHAAKMPIIDYHCHLNPQMVADDYRFKSLTEIWLGGDHYKWRAMRSNGVDECFCTGKETSDWEKFEKWAETVPYTFRNPLYHWTHLELKTAFGIDKVLNPKTAREIYDECNEKLSSQEYSARGMMRRYHVETVCTTDDPIDSLEYHIRTRESGFEIKMLPTWRPDKVMAVEVPSDFRTYIEKLSEISEITISDYNDMILALRKRHDYFAEQGCKLSDHGIEEFYAEDYTEGEIKTIFNKIYGGSELTKEEVLKFKSAMLIVLGEMDWEKGWTQQFHYGAIRNNNSRMFKQLGPDTGFDSIGEFATAKAMSKFLDRLNSKGKLTKTILYNLNPCANEVIATMIGNFQDGSIPGKIQFGSGWWFLDQKDGMERQLNALSLLGLLSRFVGMLTDSRSFLSYPRHEYFRRTLCNLLGCDVENGEIPLSEMERVCQMVEDISYFNAKNFFHF
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: RIMM_RICTY
Sequence: MNSLENLILIGIIKSCHGIQGHVILRSFTEPATKILERNLVNESGADIRIKLISQNAKGELICTFNDITTRNEAENLKGYKIFCLRTSLPELEEDEFYIADLNHLRILDQYNKEIGKIKNILNFGAGDIIEIEFLDKTTKLLPFNKEFFPTITKDYVILNYQTKV
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: X_HBVH2
Sequence: MAARLCCQLDPARDVLCLRPVGAESCGRPLSWSPGALPPPSPPSVPADDRAHLSLRGLPACAFSSAGPCALRFTSARRMETTVNAPQSLPTPLHKRTLGLSPRSTTWIEEYIKDCVFKDWEESGEELRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: HIS4_CERS1
Sequence: MILYPAIDLKDGQCVRLLRGEMEAATVFGDDPAAQAAAFEAAGCEWVHLVDLNGAFAGRPVNAAAVEAILARIAVPAQLGGGIRDMATIALWLEKGLARVILGTVAVENPGLVREAARAFPGRVAVGIDARKGRVATKGWATETDVMATDLARSFEDAGVAAIIYTDIDRDGAMAGPNIEATDALARAVSIPVIASGGVSSLADLLALRDTGSIAGAISGRALYDGALDLTQALQALRT
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_BORPE
Sequence: MAKASTSGASRVRKKVKKNVSDGIAHVHASFNNTIITITDRQGNALSWATSGGAGFKGSRKSTPFAAQVAAETAGRVAMEYGIKTLEVRIKGPGPGRESSVRALNALGIKISSIADITPVPHNGCRPPKRRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FEZF1_DANRE
Sequence: MDSALYHSAGIFGAPSASTGGSMIASSKPLAFSIERIMARTPEPKSIPFPNLFQAPVGKAEPKQSPAPLHCMIPLMPLACEPPHKLHINGLDHPDTFAYNANELLSIGLNYKNEQQDAAPAIGQYKLFRPRVVNQSSFHAMGAAVCYLNCGEGACPPHAGLVNLHPMASYLLNTPLHARQKSLFSSEKSKQGAVADRCPPGVSFKELSHSHLHHYMKESAHILSEKLFKNSAAKVNSGSPQTKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFICEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHIRKLHDISPGPHSPPTPTGNTEGQ
What is the function of this protein?
Transcription repressor.  Involved in the development of the forebrain region (By similarity).
What are the official names of this protein?
Fez family zinc finger protein 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATG4_CHAGB
Sequence: MEVALAVGAEASRVSRRILQKIWDPEPINDRDSNEPVWCLGRSYKLAPETPSPVTTATSPVDGAIDAAPAPIATPGTTNRQAIDTPPDSLASSFDSSLAYDNRNQDSGWPPAFLDDFGSRIWMTYRTGFEPIPRSTDPKAASALSFTMRLKTSFGDQTGFSSDTGWGCMIRSGQSLLANALLISQLGRDWRRTTDPGAERNIVALFADDARAPYSLQNFVKHGAIACGKHPGEWFGPSATARCIQALADQHESSLRIYSTGDLPDVYEDSFLATARPDGETFHPTLILVCTRLGIDKINPVYEEALISTLQMEQSIGIAGGRPSSSHYFVGVQRQWLFYLDPHHPRPALQYRENPLNYTLEELDSCHTRRLRYLHVEDMDPSMLIGFLIQDEDDWDMWKSAVKHVQGKSIINVSRHDPARGMGGARAEAIDEVETLSDDDDVDTVLEQ
What is the function of this protein?
Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine.  ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.  In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components.  ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
What are the official names of this protein?
Probable cysteine protease ATG4, Autophagy-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Preautophagosomal structure.
Protein: ENGB_STRP3
Sequence: MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSFINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPHGKWNKHESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: Y693_STAA9
Sequence: MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
What are the official names of this protein?
Probable transcriptional regulatory protein SaurJH9_0693.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_PROMA
Sequence: MHLGCEKNLVDTEHMMGLLDQGGYSISTNPSEASLVVVNTCSFIQDAREESVRVLVGLAEQDKEIIIAGCLAQHFQEELLQSIPEAKAIIGTGDYQNILNVLQRIEQGEIVNQVSNNPTFVGDEKLPRFRTTGKAVAYLKIAEGCDYSCAFCIIPKLRGMQRSRSIESIVAEANQLAKQGVKELILISQITTNYGLDLYGRPCLADLLRELGDVEIPWIRVHYAYPTGLTSEVIKAFREVPNLLPYLDLPLQHSHPDVLRLMNRPWQLDLNASLLDRIRSELPDAIFRTSLIVGFPGETEEHFNHLVSFVQTQQFDHIGVFTFSSEAGTKAASLANQIPFSVAEARKDKIISIQQPIAELKNQNWIGRTVDVLIEREDKDSAEFVGRCARFSPEVDGFVRLQINNTFTNQLNIGMMTPALITGADLYDLTGQVV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_CLOK5
Sequence: MSKKCEICGKGVVFGVQYSHSHRQSKRTWSPNIRKIKAIVKGTPRTIHVCARCLRSGKVQRAI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TRBJ_SINFN
Sequence: MPRRCSMSNNLLAGLAVVAVTVGTGEPADAGTATGVATEWTQVLNNGELVALVGKSNEQIQNQLTQISQFAQQIETQLNIYQNLLQNTATLPSHMWGQVERDLNRLRSIVDQGQSIAFSMGNADHVLQQRFQSYATLKTNLPRNETFSSTYQAWSDTNRDTIASTLNAASLTADQFDSEETTMSSLRSMSETADGQMKALQVGHEIAAQQVGQMQKLRGLVSQQMTMMGTWLQTEQTDKDLAQARREKFFNADVKSIPEGQKMEPRW
What are the official names of this protein?
Probable conjugal transfer protein TrbJ.
What is the protein family that this protein belongs to?
To A.tumefaciens Ti plasmid TrbJ.
Protein: Y1433_METJA
Sequence: MNDKRYMLIIAICLIFLSILVYSIHFLIFGKVDYILSYFLLHLAFVPIEVLLVSLIIEKILDYREKKKILEKLNMVVGSFFNSVGEELLKIILEGDVGNIRDYLKISDEWNDKTYEETKKLLMNYDCNIDIEKIDLYKLKNLLERNKEFLLRLMENPLLLEHESFTELLLAVFHLADELHRREDLSNLPKSDLDHLKNDIIRVYKLLIIQWLNYLMHLKDNYPYLYSLCLRANPFDNKSIIIEEDDK
What are the official names of this protein?
Uncharacterized protein MJ1433.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.