PharMolix/UniProtQA huggingface dataset:
Protein: ATG3_VANPO
Sequence: MLRSTLSSWREYLTPVSHKSTFLSSGQITPDEFVQAGDYLCHMFPTWEWNKAGNDVLFRNFLPEDKQFLVMRKVPCNVRAKQFVNIDDSASEAFVQGINDEDGSIENGWMIGGGETDHLSKHSLSSGDVTPSGNNTKTMDETTPDIDDLMESMGIEDTDDIIDTPQNTDRRYYDLYITYSTSYKVPKMYIVGFNGSGSPLTPEEMFEDIAPDYRSKTATIEKLPFYKNTISSVSIHPCKHANVMRILLDKVLVVKRRRREEMSENHNEHKPNPESDEWEDLQNDVDDTIRADQYLIIFLKFITSVTPGIEHDYTMEGW
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8.  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8.  The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme ATG3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD3Z_SHEEP
Sequence: MKWTALVIVAVLQTQFPVTAAQSFGLLDPKLCYLLDGILFIYGVIVTALFLRAKFSRSADAPAYQHGQNPVYNELNVGRREEYAVLDRRGGFDPEMGGKPQRKKNPHEVVYNELRKDKMAEAYSEIGMKSDNQRRRGKGHDGVYQGLSTATKDTYDALHMQALPPR
What is the function of this protein?
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response.  When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.  All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.  Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways.  CD3Z ITAMs phosphorylation creates multiple docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme.  Plays an important role in intrathymic T-cell differentiation.  Additionally, participates in the activity-dependent synapse formation of retinal ganglion cells (RGCs) in both the retina and dorsal lateral geniculate nucleus (dLGN).
What are the official names of this protein?
T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain.
What is the protein family that this protein belongs to?
Belongs to the CD3Z/FCER1G family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HSCB_SHEB5
Sequence: MNYFELFKFSPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQTLKDPIRRAEHMLSLRGIELSHETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDALYQSFAEYRAQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAKLHDELTRVEDALLD
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: PLSX_CLOBJ
Sequence: MIIAVDGMGGDFAPELVVEGCIQAVKEYEGIHIIITGKKELIKNELDKREYNGNKIEILNAEEVISTNEAPVKAIRRKKDSSMVKALELVKEGKAQAVISAGSTGALMAGATFVLGRIKGINRVCLAPLLPGAKAPFMIADAGANVDCKAEYLVQFAMMGKVYFESVLGVKSPTVGLVNIGAEEEKGNELTKAAYKLLKDTDFNFIGNIEPRDIPRGEVNIAVCDGFIGNTVLKTYEGVASNLFSMLKKEIMASTRGKIGGALLKPVFKDFKKKFDYTEYGGSPFLGAKGICIKAHGSSDAKAFKNAIRQAKICYDKKIIEEIENNLGNLIENNI
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: Y667_XYLF2
Sequence: MKPPEHSLIIISGLSGSGKSVALKTFEDLDYYCSDNLPVELLPHFLRRRLRVAELSDQRIAIGIDIRSGSNISELDQWRHTAKHYNIKAHLLFFDASNETLLKRYADTRRRHPLSHLGLSLPEAIALERELTAPLREAAEAVIDTSTFNVHQLRRHVVTEFALTHSDKLSLLFESFAYKRGVPTEADFVFDARILPNPHWEPELRSLTGRDSNVRDYMEQQPDVILYLTQITEFLDTWLARLQADTRSYVTVAFGCTGGKHRSVYLAEQMARHAREKGWSEVATFHRELE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein XfasM23_0667.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: FOLM_SHIFL
Sequence: MGKTQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAIDGLINAGAQCIQADFSTNDGVMAFADEVLKTTHGLRAILHNASAWIAEKPGAPLADVLACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHVAYAASKAALDNMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVDYLLTSCFVTGRSFPLDGGRHLR
What is the function of this protein?
Catalyzes the reduction of dihydromonapterin to tetrahydromonapterin.  Also has lower activity with dihydrofolate.
What are the official names of this protein?
Dihydromonapterin reductase, H(2)-MPt reductase, Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FolM subfamily.
Protein: GCSP_BORA1
Sequence: MSRALDTHSDFIPRHIGPSEADQAKMLATIGCSSLDALLEEVVPPRIRNQAPLALPGARSEPDVLAELKQMAARNKVFRNYIGQGYYGTHTPNVVLRNVLENPAWYTAYTPYQPEISQGRLEALLNYQTMVADLTGLDISNASLLDEGTAAAEAMTLARRSAKSKSAVFFVSQHCHPQTIEVVRTRAQGLDIDVLVGDESQGLPECFGVLLQYPHSLGGVVNYRELAEAAHAQGAVVACATDLLALALLTPPGEWGADIAVGTAQRFGVPFGFGGPHAGFMACRDAFKRNMPGRLVGVSKDAQGNPALRLALQTREQHIRREKATSNICTAQVLLAVMAGLYAVWHGPAGLRRIATRVHTFAGVLRQHVQALGLTVENDSYFDTLLINTGPATPAVLRAAECAHINLRRVDAGRVAVSIDETVTVEDLQALINVFAAGLGKDDITLDAATLAPEAGLPAGTVRTSPILSHPVFSSVQSETDMLRYLRKLADKDLALDRSMIPLGSCTMKLNATAEMIPITWPEFALIHPFAPADQTAGYRELIERLSAALCEITGYDNISLQPNSGAQGEYAGLLAIRGYHQARGEHQRNICLIPSSAHGTNPASAQLAGMDVVVVASDDHGNVDLDDLRAKIEQVGDRLAALMITYPSTHGVFEETVTEICERVHAAGGQVYLDGANMNAMVGVAKPGKFGSDVSHLNLHKTFCIPHGGGGPGVGPVAVRAHLAPYLPGVLNEQGKLDAEAKVGPVSAAPYGSAGILAIPFVYISLMGAEGLRRATEVAILNANYVATRLREYYPVLYAGRHGRVAHECILDIRPLKESIGISAEDIAKRLMDYGFHAPTMSFPVAGTLMVEPTESEGLAELERFIDAMIAIRAEVAQVERGERDREDNVLKNAPHTAQMLLAEEWHHAYPRQQAAYPLASLRDGKYWPPVARVDNAYGDRNLVCSCLPIEAYI
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: WCAD_ECOLI
Sequence: MSTSIRICSYLLLPLIYLLVNVKIAQLGESFPITIVTFLPVLLLLFLERISVKKLMIALGIGAGLTAFNYLFGQSLDASKYVTSTMLFVYIVIIIGMVWSIRFKTISPHNHRKILRFFYLVVGLVVALAAVEMAQIILTGGSSIMESISKYLIYSNSYVLNFIKFGGKRTTALYFEPAFFALALISIWLSIKQFGIKTPKTDAMILAGIILSGSFSGVMTFILFYLLEWAFQYLNKEAIKKKLPLALISLAVFLVGVVIAFPYISTRLGDLGTEGSSSYYRIVGPLVMVGYSLTHIDGVVRFGSLYEYVASFGIFNGADVGKTIDNGLYLLIIYFSWFAVFLSLWYMGKVIKMMINAFGDNRNFRVQLYLFTPVSLFFTGSIFSPEYAFLIVCPFILRKALNITR
What are the official names of this protein?
Putative colanic acid polymerase.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OR46A_DROME
Sequence: MSKGVEIFYKGQKAFLNILSLWPQIERRWRIIHQVNYVHVIVFWVLLFDLLLVLHVMANLSYMSEVVKAIFILATSAGHTTKLLSIKANNVQMEELFRRLDNEEFRPRGANEELIFAAACERSRKLRDFYGALSFAALSMILIPQFALDWSHLPLKTYNPLGENTGSPAYWLLYCYQCLALSVSCITNIGFDSLCSSLFIFLKCQLDILAVRLDKIGRLITTSGGTVEQQLKENIRYHMTIVELSKTVERLLCKPISVQIFCSVLVLTANFYAIAVLSDERLELFKYVTYQACMLIQIFILCYYAGEVTQRSLDLPHELYKTSWVDWDYRSRRIALLFMQRLHSTLRIRTLNPSLGFDLMLFSSIVNCSYSYFALLKRVNS
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity).
What are the official names of this protein?
Odorant receptor 46a, isoform A.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CP054_HUMAN
Sequence: MPLTPEPPSGRVEGPPAWEAAPWPSLPCGPCIPIMLVLATLAALFILTTAVLAERLFRRALRPDPSHRAPTLVWRPGGELWIEPMGTARERSEDWYGSAVPLLTDRAPEPPTQVGTLEARATAPPAPSAPNSAPSNLGPQTVLEVPARSTFWGPQPWEGRPPATGLVSWAEPEQRPEASVQFGSPQARRQRPGSPDPEWGLQPRVTLEQISAFWKREGRTSVGF
What are the official names of this protein?
Transmembrane protein C16orf54.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NADE_CHLPB
Sequence: MNTQCLHLNYALVEDILLAFIRNEIRKFGFRSAVFGLSGGIDSAVVCELAKRALGPENVLAVLMPYRTSSPESVNDARLMVEKTGVRSEEVEITGVVDAFFDGVSGAGNLRMGNVMARARMLYLYDISARDGRLVIGTSNKTELLLGYGTLFGDMASAVNPIGDLYKTQLWGLARHLQIPEELVSKIPSADLWEGQSDEADLGFGYGEVDLLLYMMLEKRMSRSDIIEAGIEESFYDKVRKMVVRNQYKRMMPVIAKISARTPGIDFRYARDWQEVK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: CBID_META3
Sequence: MIYDFLKEKKFGYTTGSCVVAGAYCGIYYLKHSVKLNIVELENSKNDKLIIPIEDVKLGKIATIKNINNTGKIKPNRATTIVKKFSGEDIDITNGIDIVVDVELLKMEKDKPKIEIVGGNGVGIVTKDGLQIKKGEYAINPKPREMIKNNIINLLDDDERAIIKITIPKGEELAKKTLNPKLGIIGGISILGTTGIVRPMSNEAYKESLAPQIDVALANNYKKLIFTPGNIGTKYAKIKYGVDDDNIVEVSNFWSFMLDKAVEKGVKDILIFGHSGKIIKLAGGIYDTHSKVADARNEILTAYSSPFINDKQILKNILYSNTTEEIVKILEKENILHEVFNLIAERVVERVSSRWEGIKFSCVIIDMKGDILGSHIYS
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: NUOCD_AERS4
Sequence: MKLTRDFPSNYTMAQWQPSDHQDAQVVGELFSHFGAERFTVQSTRTGVPVIWLARELLLDVVGFLRKLPSPFVMLYDLSATDERLRSHRDGLPQSDFTVFYHFISIDRNADVMLKVPLAESDLHLPTLTGHFPNANWYEREVWDLLGITFDGHPHLTRIMMPKSWQGHPLRKDYPARATEFDPFMLDAAKQDMEQENLLFKPEEWGMARGNENEDYMFLNLGPNHPSAHGAFRLVLQLDGEEIRNCVPDIGYHHRGAEKMGERQSWHSYIPYTDRVEYLGGVMNNLPYVLAVEKLAGIKVPNRVDVIRVMMAELFRIQSHLLFLGTYIQDVGAMTPVFFTFTDRQKIYTIIEAITGARMHPAWFRIGGVAHDLPKGWQRLVQDNLLSWLPKRLMDYEKAAMRNSILRGRTIGVSAYTTEQALAWGTTGAGLRATGLNFDVRKWRPYSGYDQFDFEVPVGSNGDAYDRATVRIEEIRQSLSIIEQCMKNMPEGPFKADHPLTTPPPKDRTLQDIETLITHFLQVSWGPVMPAAESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSFAHLQQIPSVIKGSMVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYGA_HAEIN
Sequence: MSTKFNVKTFQGMILALQEYWANQGCTIVQPFDMEVGAGTSHPMTALRALGPEPMAFAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLEMLGFDPTKNDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEVTYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEHANTDFLFYCFDQYEKEAQELLALEKPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRALTKGVAEAYYASREALGFPGCKK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPB_LISMO
Sequence: MNLEETMPLVFERSIPGRIGFSLPESDVPETNAGDYFDQAYIRSIPADLPELSELEIMRHYTNLSNHNFGVDSGFYPLGSCTMKYNPKINEKVARFPGFANIHPNQPESSVQGALELLYDLQTSLVEITGMDEVTLQPAAGAHGEWTGLMLIRAFHEKNGDTKRTKVIIPDSAHGTNPASAAVAGFDVVTVKSNEKGLVDVADLKKVVGEDTAALMLTNPNTLGLFEKDIVEMAEIVHEAGGKLYYDGANLNAIMAKVRPGDMGFDVVHLNLHKTFTGPHGGGGPGSGPIGVKKELIPFLPTPVLTKKEDIYTFDYNYPDSIGRVKPYYGNFGINVRAYTYIRTMGPDGLKLVTEYAVLNANYMMRKLQEAYDLPFDQVCKHEFVLSGNRQKKLGVRTVDIAKRLLDHNFHPPTVYFPLIVGEAIMIEPTETESKETLDSFIDTMLKIAKEAEENPEIVQEAPHSTYVKRLDETRAARKPILRYQKEV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: ASTD_VIBVY
Sequence: MTQWIAGEWVEGLGEEFTSLSPYDNQVVWRGKGATAEQVEMAVKAARQAFVGWKKLSVAEREAMVLAFAEQVKENSEEIAQVIAKETGKPLWETRTEAAAMAGKIAISIRAYHERTGESQKEAAGNQIVLRHRPLGVMAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSEQTPWTGELAMKLWQAAGLPQGVINLVQGGKETGIALAESKGIDGLLFTGSANTGHLLHRQFAGQPGKMLALEMGGNNPMVITDHYGDLDATVYTIIQSAFISAGQRCTCARRLYIPLGEKGDALITRLVEATKKLRVDQPFAEPAPFMGPQISEAAANFILAAQANLQSLGGESLIEAKAGEAAFVTPGIIDVTNIAELPDEEYFGPLLQVVRYQTLEQAVELANDTRFGLSAGLVSTDDGEWQYFVDHIRAGIVNRNRQLTGASGDAPFGGPGASGNLRPSAYYAADYCAYPMASMEGEETLLPATLSPGVEL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: RL11_LACPL
Sequence: MAKKVANVVKLQIPAGKATPAPPVGPALGQAGINIMGFTKDFNARTADQAGMIIPVVITVYEDRSFDFITKTPPAAVLLKKAAGVESGSGEPNTKKVATVTKDQVKQIAETKMQDLNAADVEAAMRMIEGTARSMGFTVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: T1R1_METJA
Sequence: MDYLKYGIEVVVKKSEKRKFKLIDYKNIDKNTFFYLCEAEFKGNPKNSRPDITLFINGIPVVIIEAKATLKIDSHLEGISQIRRYEKFSPDLFRFVQFAISYGEEQLYTPTMPNWYKENIHLPAYYWRIRQKINGKKVVKDDIFYILNPSILLEIIRYFIFYRKDEYSKTKTLSKIIARYNQYFATKKAMKRIDEYLSGDSKNKGLIWHWQGSGKTYTMFFIANYFLDKYFSENPVIFFVVDRVDLERQSKEFYEAIQEKKFKTILKRIDSINKLYEVIKSIKMSELSNKVIVRGIYTTTIQKFQYERSKKEKDNNKEKDKDDEDLDLSKPIEEIIKKIEDKLKKEEKEGKIKGLKDLLIILAFIYLKHLKEKNPEEYKKHIENLKKLKDKDKKEEYLINLGNIKRKHILILIDEAHRTQYGILGGMRKITFPNAITFGFTGTPVFKNEKNTFTEFSYPEKGEFYLDVYFIGDSIKDKFTLPLTYQIVKEGDIKSEGIQITLDEEDIKEFIDEWIKRGEDINLFDRKKLPKYINKSKTILLNPKRIDKVAKYIVDRIEEDTENFKFKAMVVAVNRLGCVRFKKALDKYLKEKFGDEAEKWAEVVMTYHHNEEEKEIIEYMKKLKKERNSNDFNEINQIIREEFLNSENPKILIVTDMLLTGFDAPRLKVMYLDKPLYGHRLLQAIARTNRPYPDKEFGLIVDSVGLFKVLTETMALYNMLAEEEIREDFKNNLISSIDEIFQEFKLKLEMVKESLKNLKINDEDLSIDVNTLKTLTKNKDFNNNELKEKLDLIAFYAEDGKNARILKLIDDLKAVIKLYKALGSYPQKIFYIEDIELLSFIYAYLIKKLKPKKKSNRKFWEELISFIHNKMLVDDLTVIEEINLNPDDLDKILKENIGKREIKRAVANYYFILKNSILDKQHDPIYKEILERLERLRRDWIMKRIDDKIYLNAIKNLMELKNNYDKKIKGKSSIERIKESISTYIGENILKDQDIKLNLENTEKLITKMQNLNKLSKLQRKKFKKELSCALLEDLLKELKGKIKDEDAKKVAELSDNLVSEFILKEIWGENYENQ
What is the function of this protein?
The restriction (R) subunit of a type I restriction enzyme that recognizes 5'-CAAN(7)TGG-3' and cleaves a random distance away.  The R subunit is required for both endonuclease and ATPase activities but not for modification.  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage.
What are the official names of this protein?
Putative type I restriction enzyme MjaVIIP endonuclease subunit, MjaVIIP, R protein.
What is the protein family that this protein belongs to?
Belongs to the HsdR family.
Protein: ISCR_ECOBW
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: RK2_PHYPA
Sequence: MTIRLYKAYTPGTRNRSVLGFKELVKTNPQKKLTFWQHNKQGRNNRGVITSRFRGGGHKRLYRQIDFRRNKKNISGKITTIEYDPNRTANICLVHYEDGEKRYILHPRGLKVGDTIISSNEAPILIGNALPLTNMPLGTAIHNIEITPGKGGQLVKSAGAVAKLIAKEGQLATLRLPSGEVRLVSQNSLATIGQIGNVDANNKTIGKAGAKRWLGKRPRVRGVVMNPIDHPHGGGEGRAPIGREKPLTPWGRTALGKRTRKIKKYSNPLILRRRKNG
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRSA_CLOAB
Sequence: MKSAKQIATALLVGMFTFSAVGCSMVEKRPEAINSKVVATIYGNQTITRGEIDKLAKGTVEQLKSQYGDSYEKNEEAVAALKKQKEQILTSLIDQKIFLKKAKDQKITLTKDEIKTNVDDVYAQYQQEFKTESEFKSQLSQYGYTVAEFKDQLKNRAISNKLIQQVVKDVKVSDDEAKKYYDSHKNSYTQSPNTVHLAHILVKTEKEAKAVKARIDKGEDFATVAKQVSTDGSKEKGGDLGDIQENDSNYDKTFMAAALKLNDNQVSAPVHTQFGWHVIKCIKKTEYPVKDFNSVKDDIKQTVLSTKQKSVYQKTLKKWESQANIDKNEKNLM
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: HO_GUITH
Sequence: MSNNLAIQLREGTSKSHSMAENVSFVKSFLSGVIDTNSYKKMMSNLYFVYKAMEEEMEYHKENDLIKPIYFVELNRSESLALDLNFYYGDTWKDIIEPSEATRVYINRIKKISKEKPLLLIAHAYTRYLGDLSGGQILKKIAQRALNVPNSQGLAFYEFDKIDDEQAFKQKYKKALDTLPVTDKMISQIVAEANIAFNLNMRMFQELEMSYIRIFTKILMQFLINSKDKLRVMLNFS
What is the function of this protein?
Catalyzes the opening of the heme ring with the release of iron.  Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae.
What are the official names of this protein?
Heme oxygenase.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL22_LATSS
Sequence: MADQITSATASAMSVRMPARKVRMVIDLIRGKSVAEAIAILEFTPRAASPVVIKVLKSAIANAEHNYDLDAENLVVTKAYANEGPTLKRFRPRAKGSASPINKRTSHITVVVSEKEA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL13_THEPX
Sequence: MKSYMAKPEEVKRKWFVIDAEGKVLGRLASQIAKILMGKHKPTYTPHVDTGDFVIVLNAEKIVLTGNKLEDKYYKYYTGYPGGLKEVQYKKLMQTKPEFVIYHAVKGMLPKNRLGRRMIKRLKVYRGSEHKHQAQKPEKLDIE
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: UMUD_ECO57
Sequence: MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLLIQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLRPTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR
What is the function of this protein?
Involved in UV protection and mutation.  Essential for induced (or SOS) mutagenesis.  May modify the DNA replication machinery to allow bypass synthesis across a damaged template (By similarity).
What are the official names of this protein?
Protein UmuD.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RM19_DROME
Sequence: MNLSTRVMLNRLTQQCVYKRIVTFSTKTAEHVIENQEEQKKEAPPTTPTSPVNRKTIIPANYRFVYPEFLPDPKVEWRNLVREKLERLDMLDRRKQIDLPEFYVGSVLAVTSSDPHAAGKTSRFVGICINRDRCGLRARFILRNVIDHQGMEVVYELYDPTILKIEVLRLEKRLDDSLFYLRDALPEYSTFDENMEAEPLEEGAPVPVNDIKVVLRPRPWLERWERQNLRGVANIDEYLKDKHRLSAAKVQKPWEKYDMMKDYRSSIPEEEQTEIFAEVHTELHALELQRKRNKRKRTFIKPKQLA
What are the official names of this protein?
39S ribosomal protein L19, mitochondrial, L19mt, MRP-L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYLM_DICDI
Sequence: MFNLYRSSLKNLKLPNINNNIKSNLVIRSYTTNINGNIKNDDDNNKFYSLSQFPYPSGALHMGHVRVYTISDCIARLKRMQGYDVIHPMGWDAFGLPAENAAIDKQVSPSEWTNLNISSMRDQLKLLNFQFDWDRELSTCNKEYYRWTQEIFLRLLKSGLAYRKSATVNWDPIDQTVLANEQVDAQGRSWRSNAIVEKKEMKQWFYKITSMADRLTDDLDQLPGWSDEIKNMQKEWIGRSYGHLIEFQSCAQKPLSNITVFTTRAETIYGVSFLAISPHHSEINQIRANLINDEKRLELDQYLKEIQEIKNKMGTQEDVENLKTFNTGLTFYQPITKKYIPLILSNFVHADYGTGAVMGVPSHNRSDYQVAKQQNLKLLPVLGIEREQQQQQQQQQQQQQLEIEEECYDYSNTGKLINSGQDTGIEFKEFIKRLEDQQLIKRQTNYRIHDWLISRQRYWGTPIPIIVCEKCGDVPVPSDQLPVELPIDIQFTGKGNLLNQLDHWKNVKCPCCGSQATRETDTMDTFVDSSWYFLRFLDSKNSQSIFSSELVNRFMPIDVYVGGIEHAILHLLYSRFITKFLKDQQLIDHSEPFKVLLAQGLVKSPTYRDSITNKPIHPSNVEFKTIKSNESGKSQQQTINKLTGNQVSVTIEKMSKSKLNGIDPKEIIDKYGSDTLKTYILFKAPPEKSLDWDTQGIEGCKKWLTRINVSIQSFLNQFDVIEGKEQHQHQQQQHQQPLPSSEFNEQQSKEVKDILFETHLTMNKVTESIDKHSFNTGIAALMELSNTLQKSSPQIKLTKEYYQSLRALTLMLFPFSPIFSQIHWKSLIDDLPQSCKSFYSENYSSFEQQSYGNSNDNDVFNQRWPKPTPSALVRDFNSLVIQFDGKTKGVESIPTSITDFSNFVQSNSKYLNRFKDKTIDQIFIGTTKTGNSINFTFKKK
What are the official names of this protein?
Leucine--tRNA ligase, mitochondrial, LeuRM, Leucyl-tRNA synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion.