PharMolix/UniProtQA huggingface dataset:
Protein: MYEF2_HUMAN
Sequence: MADANKAEVPGATGGDSPHLQPAEPPGEPRREPHPAEAEKQQPQHSSSSNGVKMENDESAKEEKSDLKEKSTGSKKANRFHPYSKDKNSGAGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGFGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRGDIGINQGFGDSFGRLGSAMIGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA
What is the function of this protein?
Transcriptional repressor of the myelin basic protein gene (MBP).  Binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter.  Its binding to MB1 and function are inhibited by PURA (By similarity).
What are the official names of this protein?
Myelin expression factor 2, MEF-2, MyEF-2, MST156.
Protein: IF4A_ASPTN
Sequence: MADKGLEDLPEGMIESNYEDVTDSFDSMELKAELLRGVYAYGFERPSAIQQRAIMPIIKGNDVIAQAQSGTGKTATFSISALQKIDPNLKACQALIVAPTRELAQQIQKVVVAIGDFMNINCHACIGGTAIRDDMKALQEGPPIVVGTPGRIQDMIQRRVLKTDQMKLFILDEADEMLSRGFTEQIYDIFQLLPQATQVVLLSATMPQDVLEVTTKFMRDPVRILVKKQELTLEGIKQFYIAVEKEEWKLDTLSDLYETVTITQAVIFCNTRRKVDWLTDKLTARDFTVSAMHGDMEQSQRDIIMKEFRSGSSRVLIATDLLARGIDVQQVSLVINYDLPANRENYIHRIGRGGRFGRKGVAINFVTADDVRMMREIEQFYSTQIEEMPMNVADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase eIF4A, Eukaryotic initiation factor 4A, eIF-4A, Translation initiation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBC_GORGO
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGV
What is the function of this protein?
Exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin-C.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. Mitochondrion outer membrane; Peripheral membrane protein.
Protein: ITR2_MOMCO
Sequence: SGSDGGVCPKILKKCRRDSDCPGACICRGNGYCG
What is the function of this protein?
Inhibits trypsin; probably participates in a plant defense mechanism.
What are the official names of this protein?
Trypsin inhibitor 2, MCoTI-II, Trypsin inhibitor II.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CTRP_PENMO
Sequence: IVGGVEAVPGVWPYQAALFIIDMYFCGGSLI
What are the official names of this protein?
Chymotrypsin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ERO1_NEUCR
Sequence: MKPASRLFYLSLFALWSPEAQCKSDESCAISPKAIVSDACASYSTLEQLNRDIKPALEDLTRTTDFFSHYRLNLFNKECPFWNDENGMCGNIACAVETLDNEEDIPEVWRAKELGKLEGPRAKHPGKSVQKEEPKRPLQGKLGEDVGESCVVEYDDECDDRDYCVPDDEGASSKGDYVSLLRNPERFTGYAGDGAKQVWDAIYRENCFQKSSFPKSASLGDTYSVPKNPAAQDFRAVMQAAGRQHMLEQQREQNPLVPFVTKTGLESEDECLEKRVFYKIVSGMHASISTHLCWDFLNQTTGQWQPNLSCYINRLHKFPERISNLYFNYALLTRAVAKLGPYLSSHEEYTFCTGDPAQDADTRAKVLAVTSKAANTVPGPVFDESIMFKNGEGPSLKEDFRNRFRNISRLMDCVGCDKCRLWGKLQTAGYGTALKVLFEFANNDTSATSSETDEIPFKLKRTELVALFNTYARLSSSLDAIQKFRAMVEESEEGQQPQSHEQIEGSENSGAHHIPDRAKKPRHVIVPTPDAADHAEASDTNTATTAVDEAKAAGVTPAPKVEHQQQVEVDNNDDDDDDDEFHEFQRQPQQPDTDPNFVYKKRTLKDDFENEFRAVFAAFKLVIRSYLNLPALIYEITITELKRFWQFYVGLPVMPRTWEFRRPSLDEL
What is the function of this protein?
Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds.  Acts by oxidizing directly pdi1 isomerase through a direct disulfide exchange.  Does not act as a direct oxidant of folding substrate, but relies on pdi1 to transfer oxidizing equivalent.  Does not oxidize all pdi related proteins, suggesting that it can discriminate between pdi1 and related proteins.  Its reoxidation probably involves electron transfer to molecular oxygen via FAD.  Acts independently of glutathione.  May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress (By similarity).
What are the official names of this protein?
Endoplasmic reticulum oxidoreductin-1.
What is the protein family that this protein belongs to?
Belongs to the EROs family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein: MSRB_ALTMD
Sequence: MSTDKKQDESIAEKDWKVELSEQEYYVCREAGTERPFTGVLLDEQRDGLYVCKCCEAPLFPSDTKFDAGCGWPSFYKQLDDGNVDYREDVSHGMRRVEIFCKQCGSHLGHVFPDGPAPTGQRYCVNSLSMTFKGEDNVEVKG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: GLYC_CAEEL
Sequence: MFARIVSRRAATGLFAGASSQCKMADRQVHTPLAKVQRHKYTNNENILVDHVEKVDPEVFDIMKNEKKRQRRGLELIASENFTSKAVMDALGSAMCNKYSEGYPGARYYGGNEFIDQMELLCQKRALEVFGLDPAKWGVNVQPLSGSPANFAVYTAIVGSNGRIMGLDLPDGGHLTHGFFTPARKVSATSEFFQSLPYKVDPTTGLIDYDKLEQNAMLFRPKAIIAGVSCYARHLDYERFRKIATKAGAYLMSDMAHISGLVAAGLIPSPFEYSDVVTTTTHKSLRGPRGALIFYRKGVRSTNAKGVDTLYDLEEKINSAVFPGLQGGPHNHTIAGIAVALRQCLSEDFVQYGEQVLKNAKTLAERMKKHGYALATGGTDNHLLLVDLRPIGVEGARAEHVLDLAHIACNKNTCPGDVSALRPGGIRLGTPALTSRGFQEQDFEKVGDFIHEGVQIAKKYNAEAGKTLKDFKSFTETNEPFKKDVADLAKRVEEFSTKFEIPGNETF
What is the function of this protein?
Interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Glycine hydroxymethyltransferase, Glycosylation-related protein 1, Maternal effect lethal protein 32, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
Protein: RL1_COLP3
Sequence: MAKLSKRARLIREKVDVTKEYDINEAVSLLKEFATANFRESVDVAVNLGIDARKSDQNVRGATVLPNGTGREVRVAVFTQGENAEKAKAAGADIVGMEDLAAQVKAGEMNFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPDVAGAVKNAKSGQIRYRNDKNGIIHTTIGKADFEPAQLQENLESLLEALKKAKPANAKGQYLKKVSLSTTMGAGVVVNQATLTQA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CD180_MOUSE
Sequence: MAPDISCFFLVALFLASCRATTSSDQKCIEKEVNKTYNCENLGLNEIPGTLPNSTECLEFSFNVLPTIQNTTFSRLINLTFLDLTRCQIYWIHEDTFQSQHRLDTLVLTANPLIFMAETALSGPKALKHLFFIQTGISSIDFIPLHNQKTLESLYLGSNHISSIKLPKGFPTEKLKVLDFQNNAIHYLSKEDMSSLQQATNLSLNLNGNDIAGIELGAFDSAVFQSLNFGGTQNLLVIFKGLKNSTIQSLWLGTFEDMDDEDISPAVFEGLCEMSVESINLQKHYFFNISSNTFHCFSGLQELDLTATHLSELPSGLVGLSTLKKLVLSANKFENLCQISASNFPSLTHLSIKGNTKRLELGTGCLENLENLRELDLSHDDIETSDCCNLQLRNLSHLQSLNLSYNEPLSLKTEAFKECPQLELLDLAFTRLKVKDAQSPFQNLHLLKVLNLSHSLLDISSEQLFDGLPALQHLNLQGNHFPKGNIQKTNSLQTLGRLEILVLSFCDLSSIDQHAFTSLKMMNHVDLSHNRLTSSSIEALSHLKGIYLNLASNRISIILPSLLPILSQQRTINLRQNPLDCTCSNIYFLEWYKENMQKLEDTEDTLCENPPLLRGVRLSDVTLSCSMAAVGIFFLIVFLLVFAILLIFAVKYFLRWKYQHI
What is the function of this protein?
May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells.  Leads to NF-kappa-B activation.  Also involved in the life/death decision of B-cells.
What are the official names of this protein?
CD180 antigen, Lymphocyte antigen 78, Ly-78, Radioprotective 105 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: FUS_NIPAV
Sequence: MVVILDKRCYCNLLILILMISECSVGILHYEKLSKIGLVKGVTRKYKIKSNPLTKDIVIKMIPNVSNMSQCTGSVMENYKTRLNGILTPIKGALEIYKNNTHDLVGDVRLAGVIMAGVAIGIATAAQITAGVALYEAMKNADNINKLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINTNLVPTIDKISCKQTELSLDLALSKYLSDLLFVFGPNLQDPVSNSMTIQAISQAFGGNYETLLRTLGYATEDFDDLLESDSITGQIIYVDLSSYYIIVRVYFPILTEIQQAYIQELLPVSFNNDNSEWISIVPNFILVRNTLISNIEIGFCLITKRSVICNQDYATPMTNNMRECLTGSTEKCPRELVVSSHVPRFALSNGVLFANCISVTCQCQTTGRAISQSGEQTLLMIDNTTCPTAVLGNVIISLGKYLGSVNYNSEGIAIGPPVFTDKVDISSQISSMNQSLQQSKDYIKEAQRLLDTVNPSLISMLSMIILYVLSIASLCIGLITFISFIIVEKKRNTYSRLEDRRVRPTSSGDLYYIGT
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with G at the virion surface.  Upon G binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis.
What are the official names of this protein?
Fusion glycoprotein F0, Protein F.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: ITPA_ANOGA
Sequence: MARPISFVTGNAKKLEEVRAILGARFPREIVAVKLDLPELQGEIDDICKLKCLEAARQVKGPVMVEDTCLCFNALKGLPGPYIKWFLDKLGPEGLHKLLDGWEDKSAQAVCTFAYTDRPDGEVILFQGRTEGDIVAPRGPRDFGWDPVFQPTGYDQTYAELPKPKKNEISHRYRALAKLAEHFADESK
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EQX3_FUSHE
Sequence: MSNVTVSVFTLDKSISEEPVLPSSFIPSSGNVFPKFTSAIPKTAWELWYFDGISKDDRSSIVIGVTRNAEGLKHGGFKVQVFVIWADERTWHRDLFFPESVVSIDESGATEGIWKHATSSSSISFSCAGDLSKASLVFDVPGIVQGDMHLEALPGDTGLDTDATLGPSVYYVRPLGRASVKAQLSLYSSDATAAEQFILGTSANGGMDRVWSPLSWPQVMTESYYLRAQVGPYAMQIMRIFPPKGSENSENQPSTMARLYREGQLICAPQHVVTRDDALITHDSLILSKQNTSDSGDAVTGEYRDKNTGYTVEFVGKGNEEQRWEFQVRHERIIWNTPTSRPGPDATGNTGFVERLYGGTIGESYEGVGTGGQCELS
What is the function of this protein?
Diels-Alderase; part of the gene cluster that mediates the biosynthesis of equisetin, a trans-fused decalin-containing tetramic acid with antimicrobial activity (PubMed:23614392).  The PKS module of eqxS together with the enoylreductase eqxC catalyze the formation of the polyketide unit which is then conjugated to L-serine by the condensation domain of the eqxS NRPS module (PubMed:23614392).  Activity of the Dieckmann cyclase domain (RED) results in release of the Dieckmann product intermediate (PubMed:23614392, PubMed:18652469).  Diels-Alderase eqx3 is involved in endo-selective Diels-Alder cycloaddition to form the decalin ring, leading to the production of N-desmethylequisetin also called trichosetin (By similarity).  Subsequent N-methylation is carried out by eqxD to give equisetin (PubMed:23614392).
What are the official names of this protein?
Diels-Alderase fsa2, Equisetin biosynthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the Diels-Alderase family.
Protein: ASTB_LEGPL
Sequence: MNVYELNMDGLVGQTHHYAGLSSGNIASTNNALSISNPQAAARQGLEKMRRLYNMGLKQGLLPPHQRPNLNLLYQLGFKGTPSEQINKAYKTAPELLSACYSASCMWTANAATVSASVDTEDNKVHFTAANLISNLHRHQEADFSKKLLEFIFSNSDYFNHHPLLPKSMGTSDEGAANHNRLCQSHAHSGINLFVYGKKVLGNHQFEQSPIKYPARQTKEASEAIARNHLLNPERVIFACQNPLAIDQGVFHNDVISVANEHVFLVHEEAFYNQTYVLDQLREKADFPLVIIQISKEQISVSEAVDTYLFNSQLITLPDQKNMILIAPAECQANLKVKTCIDGLVADPQNPINSVYYLDLKQSMRNGGGPACLRLRVPLNDYELKAMHQGILIDNDLLDILDKWVLKYYRTELKISDLADPQLLYECLDALDELTQILKLGSIYPFQS
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: FLBT_BRUC2
Sequence: MAANSKTAIRLSLRAGERIFINGAVLRADRKVSLELLNDATFLLENHVLQPEDTTTPLRQLYFAAQMMLIEPAMREQAGATFAQMLKGMFATFKDAEILNALKLVDELVHNGRVFEALKTIRAQYPREAELMGAQPVVWPVTKSGKSAGANP
What is the function of this protein?
Has a post-transcriptional repressor function in flagellum biogenesis.  Associates with the 5'-UTR of fljK mRNA and promotes its degradation.
What are the official names of this protein?
Probable flagellum biosynthesis repressor protein FlbT.
What is the protein family that this protein belongs to?
Belongs to the FlbT family.
Protein: ALK_DANRE
Sequence: MIARILYFFLWSAAFLPELQCASQRTADALTTFPTSAFINGTDRKDSNQTSTSRIKRKTLSVDFAVPSLLRYYLALFIKRPLNGDCLSFNGCYTVRANLLMRCVPLQKTIAGLLDAKLAAMNVNRSSTGQLPYRQKRPVPKVLNLGLTSASRKSNQVVVEVGEEMVKTGCGGLHVYEDAPVVFLEMDLTRILEWWLGAEGGRLRVRLMPERKVQVPGKEDKYSAAIRASDARLFIQIASSERPSSTISRNPTVAPKYWNFSWIAEDELTFPEDPVSTSDCTSKAKSCDRRPDGYYPEFAWSLTSAEDSWAIDQTMVKTKASSQGWEEGRFLTVNSSALTGPWVLSPWFRAAHRPCGLDITVFLHPRQSGRYTVWLIERDKPPLALLTTEHPHVIGWAVVHLSLAARSKPFRISSSYSQPGEIETATYDPRYSTNCTTRSSQNVTLRGRYHCRGGREINVSQLCDFSIDCPQGDDEGEHCRQFLNGSYCSFGREDCGWQPVQGRGPQWRAHPSIPQSLRSSCPSPGALLAIDSQPKGQRGSAQVRSPLFFYPLRNAPCMVKFWVCGSSNGALSLWITENSTGPEGQRSLWNSTSEANMGKGWKLITLPLFGLVDLFYLQFSADISSSSGIAFAVDNFTLSMECFLETNGEFPPVAPISPTQALFTQSNENIKTTTTLYGGPGASTESVKWIFHTCGATGQDGPTPTQCSNSYRNTNVNVTVGTKGPFKGIQMWQVPETRKYRITAYGAAGGRSVLAVHKSHGVYMTGDFLLQKDELLYILVGQEGEDACPNMVPTMDRICREQQGPSINKTQLKGGGGGGGGGTYVFKVVNGVHIPLLIAAGGGGRGYSSQSETPEEVMDRDPSIPGRNGKSGTAGGGGGWNDSAPVPQGGRPLILGGQGGEPCQAMGWKTRGGFGGGGGACTAGGGGGGYRGGSAWHDNDPRKDGDDGTSYISPDGEMYLEPLKGMEGNGEVIINPVQNCSHCESGDCHETSEGMVCYCDEELTLAPDGVSCINSTELPLLPAQPSLSHLALGLSVGTSALIAALLLAVSGVMIMYRRKHTELQSIQLELQSPDCKLSKLRASTIMTDYNPNYCFGGKTASVNDLKEVPRRNISLTRGLGHGAFGEVYEGLAVGIPGEPSPMQVAVKTLPEVCSEQDELDFLMEALIISKFSHQNIVRCIGVSLQALPHFILLELMAGGDLKSFLRETRPRLEHPSSLTMVDLLNIARDIARGCQYLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRASYYRKGGRAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSRSNQEVLEFVTNGGRMDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTILERIDYCLQDPDVVNVPLPVEYGPIPEEEERVPMRPEDPSAPSLLVSPQGTEDVPSATHSAQSKKDGEAIHMANLSTDSKLPPVPPSQPHPHHHLQTPVVTAPVPASKPSSTTSNAQDGGHVNLGFMQAHSSEKESRNRKPTNLWNPTYGSWFLQQQQKRQQVQAQRQTSGPRIPGEGQEQVGRTVTVAEALGLQQQHKQQQYQQQLQRQQQQQQQQQQQQGLCRPLLPPPPPPAPTPLLLDSATLAPVPLYRLRRFPCGNIGYGYQEQGLPMEPMQGPQLPPPHPGQQRPISLTRASGPEDSRPLLVTMGTVQDSRLPKMEGHNATVL
What is the function of this protein?
Receptor tyrosine kinase required for neurogenesis in the developing central nervous system (PubMed:23667670).  Following activation by alkal ligands (alkal1, alkal2a or alkal2b) at the cell surface, transduces an extracellular signal into an intracellular response (PubMed:29078341).  Ligand-binding to the extracellular domain induces tyrosine kinase activation, resulting in the activation of the mitogen-activated protein kinase (MAPK) pathway (PubMed:23667670).  Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif (By similarity).
What are the official names of this protein?
ALK tyrosine kinase receptor, Anaplastic lymphoma kinase 2, alk-2, Anaplastic lymphoma kinase homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GPDA_SHESM
Sequence: MKNSADITVLGAGSYGTALAISLASNGHKTLLWGHDPAHMQTLAQDKCNQAFLPGIAFPECLHIEADLAKALAASNNVLVVVPSHVFGSVLAQAKPLLRQDARIVWATKGLEPETGRLLQDVARDVLGEQYPLAVLSGPTFAKELAMGLPTAISVAGTCPKFTAELVELLHSPKRLRVYANDDFIGLQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVELTRLGEALGASTATFMGMAGLGDLVLTCTDNQSRNRRFGLALGKGCDVDTAQAEIGQVVEGYRNTKEVFTLAKRMGVEMPITEQIYQVLYQGKAPLDAAKELLSREKKSETPAQ
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_THEM4
Sequence: MADIAQKIKATGEDFEERIVEIRRTTKVTKGGKNLSFRVLAVVGNRNGKVGVGVGKAREVPDAIRKALSAARRNVFKVPIHNGTIPHEIVGRQDAAKVLLKPASPGTGIISNGTVRAVVELAGIHNILTKSSGSTNPVVLAQATVNGLKNLLSLEKIAELRDITPQEVIHGVKKEG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MSRA_ECO5E
Sequence: MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGMEIAIFAMGCFWGVERLFWQLHGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYDPSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAAMLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: RL16_SHEPC
Sequence: MLQPKRMKFRKMFKGRNRGLANGTEVSFGTFGLKAVGRGRLTARQIESARRAMTRHIKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMNGVSEVIAREAFALAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MQO_MYCPA
Sequence: MSSLARTTRADVVLVGAGIMSATLGALLRRLQPDWSMTFVERLDAVAAESSSPWNNAGTGHSALCELNYTPQRADGSIDIAKAVRINEQFQVTRQFWAYAVENGMLTDRGFVTPIPHASFVRGARAVEYLRRRQQALAPNPLFAGIELIEDADEFARRLPLMADRRDFSEPTALNWARHGTDVDFGALSRQLIGFCVRGGATALFGHQVHNLTRESDGSWTLLIRNRRTGEKHWCNAKFVLVGAGGDALPLLQKSGIGEARGFAGFPIGGRFLRADNPVLTEAHRAKVYGAPAPGAPPLGALHLDLRYVNGKPWLVFGPYAGWSPKFLKHGHFTDLPRSVRPHNLVALLGVGVTQLTLLRYLIGQLRLSAPDRMRMLREFAPTAVDSDWELTVAGQRVQVIRRDRRRGGVLDFDTTVVAAGDGSIAGLLGGSPGASTAVPIMLDVLQRCFADRYRSWLPALKEMVPSLGVTLSDEPALYEEVYSWGTKILGLDELDEERPK
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: GAR3_RAT
Sequence: MSSECLLPYYTAHSYRSMGVFNTSMGNLQRQLYKGGEYDIFKYAPMFESDFIQISKKGEVIDVHNRVRMVTVCIASTSPVLPLPDVMLLARPAKVCEEHARRARFIKGRGYKPSKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDAREDLFCYWEKLVYLLRPPVNSCISNPSIPTADTSTETKSTLVSEIHGEGDRDSKFQTSQDVSEATSAAFAGGERTQPNIAAILTTGLAKARAAGAAAGTGAAGTAGTAGAAGATGAAGATGAAGSARAAGGAGSARAAGATGSARAAGATGSARAAGATGSARAAGGNTAAAVMTPLAGLARAGTPTSPVSGVISIAATTSKSPGSGQVATGLTGTASKDQERSESSKAMAVVANITTESVDVVLAGAASFTSESPSAEGDAYGSPDTGLNVAFAGSITTKGPAEDKPEAPLVSTLQSEGYMCERDGSQKVSHTSSETQKEKRERRESDRKGSRKSSHHQRTGASRHSSSKDKGRKTSSYRSVSGHGKTREDKKEKGRGSLRDQRHSSSYRSESRTGHKSRKNRPAASGGFVSKRATKIRSFFRAFLVRPTLKTENTSGERGGVDIVTKLVEKQDIETTVEKSKDLEFSDTMASESMEKIILETKPI
What is the function of this protein?
May be involved in RNA biogenesis.
What are the official names of this protein?
Golgi-associated RAB2B interactor protein 3, Protein FAM71B.
What is the protein family that this protein belongs to?
Belongs to the GARIN family.
What are the subcellular locations of this protein?
Golgi apparatus. Nucleus, Cajal body.