PharMolix/UniProtQA huggingface dataset:
Protein: MRAY_LAWIP
Sequence: MLYNILFPLSSDYTILNVFKYITFRSVWSLITALILSILLGPYFIRWLQRINFKQQIHEDVKIHKSKTGTPTMGGVLICFSSLCSTILWSDLTNIYVWLTLLVFIGFSFIGFLDDYIKILHHQNKGFSAKVKLLAQVVVAGIAMLFLVSEPAYSTKLAFPFFKSLHPDFGYFYVPFAILVMVGASNAVNLTDGLDGLAIAPVIVSIFVLSVYIYVTGNVKFSQYLQVDYIAGVGEVAVFCGALIGAGLGFLWFNAYPAQIFMGDVGSLGLGGVLGFLAVLCKQELLLLIVGALFVLETLSVIVQVGYFKWTGGKRIFRMAPLHHHFELKGIPESKIIIRFWIISITFGLIALSALKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMB_LEVBA
Sequence: MRVRNKPWAKGYMADHLDRLVVEPEPLKGNWQSRFPSNQPLFVEIGTGKGQFIIEMARQHPDRNFIGIEIQTSVIAVALKGVVNSGLTNIQLVHTDGEAINTFFEAGEVSGLYLNFSDPWPKKRHTKRRLTSPVFLAHYADVLQPEGQLQFKTDNRGLFEYSLGSLNNFGMVFEGVWLDLHAATDGVEDIQTEYEQKFSKKGPIYQVIAHFPTNN
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: LEUC_GLOVI
Sequence: MAVSRATLFDKVWDLHTVGTLASGQTQLFIGLHLIHEVTSPQAFAMLRERGLGVLYAERTVATVDHIVPTQSQQRPFADTLAEQMIRALEDNCAEFGIRFYNIGSGSQGIVHVIAPEQGFTQPGMTIACGDSHTATHGAFGAIAFGIGTSQVRDVLATQTLALDKLKVRRIEMNGSLHPGVFAKDVILHIIRKLGVKAGVGYAYEFAGTTFEAMNMEERMTVCNMAIEGGARCGYINPDAVTYAYLKGRDFAPQGADWERAVAWWENLRSDPDAQYDDTIHFDAAEIAPTVTWGITPGQGIAVDEIVPRPEELPGEDRPLAEEAYRYMDLAPGVPIVGTKVDVCFIGSCTNGRLSDLREAANLARGRHVAPGVKAFVVPGSERVKRQAEAEGLHEVFLEAGFEWREPGCSMCLAMNPDRLEGRQLSASSSNRNFKGRQGSASGRTLLMSPAMVVAAAVSGAVADVRALLEPTP
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: KANU_STAAU
Sequence: MNGPIIMTREERMKIVHEIKERILDKYGDDVKAIGVYGSLGRQTDGPYSDIEMMCVMSTEEAEFSHEWTTGEWKVEVNFDSEEILLDYASQVESDWPLTHGQFFSILPIYDSGGYLEKVYQTAKSVEAQTFHDAICALIVEELFEYAGKWRNIRVQGPTTFLPSLTVQVAMAGAMLIGLHHRICYTTSASVLTEAVKQSDLPSGYDHLCQFVMSGQLSDSEKLLESLENFWNGIQEWTERHGYIVDVSKRIPF
What is the function of this protein?
Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.
What are the official names of this protein?
Kanamycin nucleotidyltransferase, Neo(R).
Protein: TY32_PHAJA
Sequence: QDKPFWSPPIYPH
What are the official names of this protein?
Tryptophyllin-T3-2, Pj-T3-2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GAO_TANPA
Sequence: MALSLTTSIALATILFFVYKFATRSKSTKNSLPEPWRLPIIGHMHHLIGTIPHRGVMDLARKYGSLMHLQLGEVSTIVVSSPKWAKEILTTYDITFANRPETLTGEIVAYHNTDIVLAPYGEYWRQLRKLCTLELLSVKKVKSFQSLREEECWNLVQEIKASGSGRPVNLSENIFKLIATILSRAAFGKGIKDQKEFTEIVKEILRQTGGFDVADIFPSKKFLHHLSGKRARLTSIHQKLDNLINNLVAEHTVKTSSKTNETLLDVLLRLKDSAEFPLTADNVKAIILDMFGAGTDTSSATIEWAISELIKCPRAMEKVQVELRKALNGKERIHEEDIQELSYLNLVIKETLRLHPPLPLVMPRECRQPVNLAGYDIPNKTKLIVNVFAINRDPEYWKDAETFIPERFENSSTTVMGAEYEYLPFGAGRRMCPGAALGLANVQLPLANILYHFNWKLPNGASYDQIDMTESFGATVQRKTELLLVPSF
What is the function of this protein?
Involved in the biosynthesis of germacrene-derived sesquiterpene lactones (PubMed:30468448).  Component of the parthenolide biosynthetic pathway; parthenolide and conjugates are promising anti-cancer drugs highly active against colon cancer cells (PubMed:30468448).  Catalyzes three consecutive oxidations of germacrene A to produce germacrene A acid (PubMed:24704560).
What are the official names of this protein?
Germacrene A hydroxylase, Germacrene A oxidase, TpGAO.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: RL17_SHIBS
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: LACC_STRPC
Sequence: MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSRVLNDFGETVKATGCVGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEILEKGPLLSVDEIDGFTHQFKYLLNDVDVVTMSGSLPAGMPDDYYQKLIKIANLNGKKTVLDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFEALKEVLQDELFEGIEWIIVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: COPA_STAAS
Sequence: MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLTLTETTTFKAVPGHGIEATIDHHHILVGNRKLMADNDISLPKHISDDLTYYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
What is the function of this protein?
Involved in copper export.
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRCB_HYDCU
Sequence: MQSFHVLQLIAVGFGGALGAMARFIVSNQVYAWWGRDFAWGTLVVNSLGSFAIGLIMILMIDKFHASVEMRSFLIVGFLGAFTTFSTFSFETYSFLQTGEITKAMLNIGVSVLTGLFAVWLGIWTGKQFFSP
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PFDA2_METJA
Sequence: MVNEVIDINEAVRAYIAQIEGLRAEIGRLDATIATLRQSLATLKSLKTLGEGKTVLVPVGSIAQVEMKVEKMDKVVVSVGQNISAELEYEEALKYIEDEIKKLLTFRLVLEQAIAELYAKIEDLIAEAQQTSEEEKAEEEENEEKAE
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit alpha 2, GimC subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_BRUMB
Sequence: MRAGQPKITGAKITGAIIAGGQSSRMQAGGVSGDKFLQPLGSAPVIAHVIARLQPQVDTLFINSKGDLSRFAAFGLPAVKDIAMNHGGPLVGLLTCLAHASPCRLLLTSAADTPFLPCDLASNLIRKQAETGARIILACSNERVHPIVGLWHTDLVPDLEKWLQYAEKASIFWFAKHIGFEVVNIPLAHAPRLAESYDPFFNINLPDDLLKAREINEALQA
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCH_METAC
Sequence: MISVNEMGSYVIEEMLDWSEDLKTEVTKLNSGATIIDCGVKAEGGYEAGMYLARLCLGDLADLKYSTFDLNGIKWPAIQVATDNPLIACMASQYAGWRISVGDYFGMGSGPARALGLKPKELYEEIGYEDDFEVAVLVMESDKLPDEKVVEYIAKHCGVEPENVMIAVAPTASIAGSVQISARVVETGIHKFESIGFDINCIKSGYGIAPIAPVVGNDVQCMGSTNDCVIYCGETNYTVRFEGELAELEDFVKKVPSTTSNDFGKPFYQTFKAANFDFFKVDAGMFAPARVTVNDLKSTKTISSGGLYPEILLESFGIRNV
What is the function of this protein?
Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
What are the official names of this protein?
Methenyltetrahydromethanopterin cyclohydrolase, Methenyl-H4MPT cyclohydrolase.
What is the protein family that this protein belongs to?
Belongs to the MCH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_WIGBR
Sequence: MYAIFKINGVQYKAKSGSVVCLNKISGDIGSTIEIKKIMALFNDEKIIFGQPFIKNSRIIATIKKHINGKKISIVKFSRRKHFKKITGYRQKLTNIKIIDICC
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ATPA2_LISIN
Sequence: MSIKAEEISSIIKQQIENYQSELKVSDVGTVTYIGDGIARAHGLDNAMAGELLEFSNGVMGMAQNLETNDVGIIILGPYTEIREGDEVRRTGKIMEVPVGEALIGRVVNSLGQPVDGLGPIETTGTRPIEAVAPGVMQRQSVNEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTSVAIDTILNQADQDMICIYVAIGQKESTVRNAVETLRHHGALDYTIVVTAAASQPAPLLYLAPYAGVAMAEEFMYSGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDSLGGGSITALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAINAGLSVSRVGGSAQIKAMKTVAGTLRLDLAAYRELESFSQFGSDLDAATRAKLERGKRTVEVLKQDLHKPLKVEKQVLILYALVHKYLDDVPVHDVLRFESEMNTWFDHNHPELLEEIRTTKKLPDEAKLEAALKEFKNTFVPSEEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NCBP2_DROYA
Sequence: MSASVELSSYRDQHFKGSRSEQERSLRDSCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMGLDKYKKTPCGFCFVEYYIRSEAEAAMRFVNGTRLDDRLIRVDWDAGFIEGRQYGRGKTGGQVRDEYRTDYDAGRGGYGKLLSQKIAPNTDNR
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing.  Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires Cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RGCC_HUMAN
Sequence: MKPPAAQGSPAAAAAAAPALDSAAAEDLSDALCEFDAVLADFASPFHERHFHYEEHLERMKRRSSASVSDSSGFSDSESADSLYRNSFSFSDEKLNSPTDSTPALLSATVTPQKAKLGDTKELEAFIADLDKTLASM
What is the function of this protein?
Modulates the activity of cell cycle-specific kinases.  Enhances CDK1 activity.  May contribute to the regulation of the cell cycle.  May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition.  Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.
What are the official names of this protein?
Regulator of cell cycle RGCC, Response gene to complement 32 protein, RGC-32.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic in unstimulated cells. Nuclear after activation by complement. Associated with the centrosome during prometaphase and metaphase.
Protein: PSTB_PYRAB
Sequence: MKEFAIETRNLRIYYGSNEVIKGINLKIPKNVVFALMGPSGCGKSTLLRAFNRLLDLNPEAKVEGEVRISGVNIYSPDVDPIRVRREVGMVFQYPNPFPHLTIYENVAIGVKLNGLAKGKELDEIVKWALKKATLWDEVKNRLKDYPANLSGGQKQRLVIARVLAMKPKIILMDEPTANIDPVGTRKIEELLFELKKDYTIVLVTHSPAQAARVSDYVAFIYMGKIVEVGPTRKVFENPEHELTEKYVTGALG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TTCA_BRUA4
Sequence: MNAFDPDIAEDAGSDGCHPLFRDVPTTVEFNKLRKRLLRLTRQAIEDFSMVKPGERWMVCLSGGKDSYGLLALLLDLKWRGLLPVELLAVNLDQGQPNFPKHILPDFLNRYEIEHRIEYQDTYSIVTDKLPETSTYCSLCSRLRRGNLYRIAREEGCSAIVLGHHREDILETFFMNLFHGGRLAAMPPKLLNDEGDLMVFRPLAYAAEDDLEKFATAMQFPIIPCDLCGSQEGLQRNAMKAMLTDIEKRMPGRKDTMIRAMTNVRPSHLLDRKLFDFAGLMLNGEGEGDHAV
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSA_STAA8
Sequence: MEEHYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREKNDVQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLDYVTINYHDNEETEEDVIDVKDKDNESKLGGFDWFKRKTNKKDTHENEVESTDEEIYQSEDNHQEHKQNHEHVQDKDKDKEESKFKKLMKSLFE
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: RL15_MESM1
Sequence: MNLHELKYNEGARKEKHRVGRGHAAGKGKQAGKGQSGQLKRTGSKPGFEGGQNPWYRRVPKRGFNNVNHIEYQVISIETLDAAFPDKAEINPEVLHEKRIARNKNLPIKLLANGATKKKFTIKLNAASKKAIELIEKAGGKVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RL2_RICB8
Sequence: MALKSFNPITPSLRELVQVDRTSLWKGRPFKALTKGISKTGGRNNQGRITSWQRGGGHKRLYRVIDFKRNKLDISAIVERIEYDPNRTAFIALIKYEDGEHAYILAPQKLVVGDKIISSKDADIKIGNCLPLRYIPIGTTLHNVEMKVGKGGQIARSAGTSVDLVGKDSGYAQIKLKSGEFRLVPLDCMATIGTVSNPDQKNINLGKAGRNRWLGWRPHVRGVAMNPVDHPHGGGEGKTSGGRHPVTPWGFPTKGKKTRKNKRTSKFIIKKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NDK_LEPBA
Sequence: MERTFIMLKPDAVKNKHIGDILQRIEKEGFKILGMKFLKLSLEDAKQFYAVHAARPFYNDLCTYMASGPIVACALERDNAVAHWRDVIGATDPKEAKAGTIRALFAESKEANAVHGSDSVANALQEIAFFFKGYELN
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AL1A2_CHICK
Sequence: MTSSKIEMPGEVKADPAALMASLHLLPSPTLNLEIKHTKIFINNEWQNSESGRVFPVYNPATGEQICEIQEADKVDTDKAVRAARLAFSLGSVWRRMDASERGQLLDKLADLVERDRAVLATMESLNSGKPFLQAFYVDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGFGPIVGAAIASHVGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIYVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGITEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTVDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGESGLREYSEVKTVTIKIPQKNS
What is the function of this protein?
Converts retinaldehyde to retinoic acid.  Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal.  Can metabolize octanal and decanal, but has only very low activity with benzaldehyde, acetaldehyde and propanal.  Displays complete lack of activity with citral.
What are the official names of this protein?
Retinal dehydrogenase 2, RALDH 2, RalDH2, Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, RALDH(II).
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF12_NEOYE
Sequence: MINWQVIAQLVSLGVIVLVGPAVIILLSLKRGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GET3_NEUCR
Sequence: MSTAVINADDDHMEPTLQSILDQRSLRWIFVGGKGGVGKTTTSCSLAIQLAKVRRSVLLISTDPAHNLSDAFSQKFGKEARLIDGFDNLSAMEIDPNGSIQDLLAGQGENEGAGDMGGVGGMMQDLAFAIPGIDEAMSFAEVLKQVKSLSYETIIFDTAPTGHTLRFLQFPSVLEKALAKVSQLSSQYGPLLNGFLGSNGTLPNGQNLNEMMEKLETLRATISEVNTQFKDERLTTFVCVCIPEFLSLYETERMIQELASYGIDTHSIVVNQLLFPKPGSDCEQCTARRKMQKKYLDQIEELYDEFNVVKMPLLVEEVRGKEKLEKFSEMLVKPFVPPQ
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase get3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: EPMA_PHOLL
Sequence: MSETANWQPSAAIANLLKRATILAEIRRFFADRGVLEVETPAMGQFTVTDIQLFSFQTEFVGPGAADGMTLYLMTSPEYHMKRLLAAGSGPIYQLGRCFRNEEAGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQILDCESAESLSYQQAFLRYLDIDPLSAEKEKLREIAAKLDLSNIADIEEDRDTLLQLLFAVGVEPHIGTEKPTFIYHFPASQASLAEISKEDHRVAERFEVYFKGVELANGFRELTDSHEQCQRFERDNRKRAALGLPVRPIDENLIGALKQGMPECAGVALGVDRLVMLALGAEKLSDVMAFSITKA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: DBP10_PHANO
Sequence: MAPRASSPALSENEFDIFDALAGGDEAAQPMRVTADLGIDLEFGSDDGSDDEAFIAAKQAAANRKNANAPGKSGKKGGGFQAMGLNVALLKAIAQKGFKIPTPIQRKAVPLILQGDDVVGMARTGSGKTAAFVIPMIERLKTHSAKVGARGVIMSPSRELALQTLKVVKEFGRGTDLRTILLVGGDSLEEQFNSMTTNPDIIIATPGRFLHLKVEMGLDLSSVQYIVFDEADRLFEMGFAAQLAEILYALPTSRQTLLFSATLPKSLVEFARAGLQEPKLIRLDAESKISPDLKSAYFTIKSGDRDGALIHLLENVIKMPVGQTEVWKQAKEEADNLSKGKKRKRGSGNPKDAPVEESTIIFAATKHRVEYLSTLLKAAGYPVSYVYGNLDQTARQEQVKDFRAGLTRILVVTDVAARGYRHATHKPRHQLRLPFSTKNLCSSSGEDGPRWAEGLGIQPVQTCRSAISHRLTNVPWQTPSGCLAPYQLEPSVELVNKQLTDDEDLVNLLNVAEKGERQYQRTRNQASNQSVHRAKDLASDSKFAETHMLFNDEMHDALRAKEDMLERIQGFRPAETVFEIGKRGTNSEAAEIMRKRRVAVERQKTKQAFNKANDESSGLTRPTADALPDDELDSEDDQQAAVGDYESESDELEVTVSQPESKKSGKDVWRSDEFFMSYLPKENFAEEKAYGVQGGDAGNSNFVSAARSAEMSLVNDEIQGFADASKPRMRWDKKSKKYVSRANDEDGSKGAKMIRGESGQKIAASFRSGRFDDWRKANKVKMQRVGEMEAPNRSTQFNSGGPRYKHKAEKAPKQADRYRDDYHVQKQRVQEAKEKRIGHFKDGGAKNELKDVDTVRKERRVQEKRKEKNARPSKKRKF
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.