PharMolix/UniProtQA huggingface dataset:
Protein: PLPL_DEBHA
Sequence: MEKTNRKKLFDEDIDYVNEDHISSFAKALAWEEQYEILENEKSGASSDKESQDAATIQKETEELDDLGADELSTALNGMHKPDLISSKSDWWPINTSKSIPKTKIRKKSKKSSVNEGHSKITNEFRSSASYTMLRWPILIFISCWISLLCFMYIIVRAYVALSEYFLTWVGKRKELRNKLRASQNYEEWVQNALELDRFLNLDKWSENPKFSYYDSKTVELTISKLASLREEGRDNDLMVILQGCIKKNFAGIENRQLYSHRYYGTKYLVEKYIDEVIVCIDKVIESQQISFNDKRRFFRTVSKNYGKTALCLSGGACFTYTHFGIVKALLDNDLLPSIISGTSGGGLIAALSCTRTDDELKKLLVPELARKITACEDPWYVWIPRWWRTGARFDSLEWARKANFFTRGSTTFYESFKRTGRRLNISTVPSNPHSPVILCNNITSPNCIIWSSLLASSAVPGILNPVVLLMKDLKTDRVVPFSLGSKWRDGSLRTDIPIDALNTYYNVNFSIVSQVNPHISLFFFAPKGTVGRPVAIPRRKTHKEKYASLRGGFIATALEQLFKLEITKWLQMIKSLDLLPHLLEQDWSNIWLQRFSGSITIWPRNRLKDFWYILSDPTEERLAEMLSKGERAMFPRILFVKHRLSIEKAIEKGRKQTKLSANFNTLTSSDSGRTELSPEAAELQVEPAMFDDDEYDSDSSDDEVLSPNNKKHIDKFGTPNTEDGDDDEDAYEYYDDDDYGLSTEDEANQENTGNSQGEENDTGSRFLKSFFRAGSRDSKLHRRNTVF
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein DEHA2B04136g.
What is the protein family that this protein belongs to?
Belongs to the PLPL family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NCALD_PONAB
Sequence: MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDESTPGKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAGQF
What is the function of this protein?
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.  Binds three calcium ions (By similarity).
What are the official names of this protein?
Neurocalcin-delta.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
Protein: RS10_AGRVS
Sequence: MNGQNIRIRLKAFDHRVLDASTREIVSTAKRTGASVRGPVPLPTRIEKFTVNRSPHVDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: Y2132_SYNSC
Sequence: MAGHSKWSQIKRTKAVVDAKRGAVFTRLGREIMVAARAGADPAGNFQLRTAISKARAAGVPASNIERAIAKGSGQAGDGAQLEDVRYEGYGPGGMAVLVEALTDNRNRTAADLRLAFSKNGGNLGENGCVAYLFEHRSEVILNAGPDDEERLLESLLELDADGYELLDGAVVVHGPFEALESLQDGLRHADWNVREWGHHWSAQTSVSVNDPETARSCLKLLDALDGLDDVRSVSANLDLADELEID
What are the official names of this protein?
Probable transcriptional regulatory protein Syncc9605_2132.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_SPAEH
Sequence: VLSPEDKNHVRSTWDKIGGHGAEYGAEALERMFTSFPTTKTYFPHFDVSHGSAQVKAHGKKVADALANAAGHLDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLANHHPAEFTPGVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MOAB_STACT
Sequence: MTKNEHVNVKLDRDIQCAVLTVSDTRTPETDKGGNLAKELLSEINVEIKPEHYAIVKDDKQAITEQLQQWLAEDVDVIITTGGTGIAQRDVTIEAVTPLLSKEIEGFGELFRYLSYAEDVGTRALLSRAVAGTVGEQLIFSVPGSTGAVKLAMNKLIKPELNHLIHELTK
What is the function of this protein?
May be involved in the biosynthesis of molybdopterin.
What are the official names of this protein?
Molybdenum cofactor biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the MoaB/Mog family.
Protein: GL_HCMV5
Sequence: MCRRPDCGFSFSPGPVILLWCCLLLPIVSSAAVSVAPTAAEKVPAECPELTRRCLLGEVFQGDKYESWLRPLVNVTGRDGPLSQLIRYRPVTPEAANSVLLDEAFLDTLALLYNNPDQLRALLTLLSSDTAPRWMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVPPSLFNVVVAIRNEATRTNRAVRLPVSTAAAPEGITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELKQTRVNLPAHSRYGPQAVDAR
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH (By similarity).  In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope.  The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA.  The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: SYP_ECO81
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVLMPVVQPSELWQESGRWEQYGPELLRIADRGDRPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_HAEDU
Sequence: MPELPEVETCLRGIEPYLAGQTIQQIVIRTPKLRWPISAELCAMSGAKILALSRRAKYLIIHTERGDILVHLGMSGSLTLLNSSQPTKASKHDHVDLITEAGIILRYNDPRKFGAWLWAKQAENYPLITKLGPEPLSDTFTSDYLFKKSRNKTVAVKNFIMNNDIVVGVGNIYASESLFMAGVHPELAAQNLTEKQCVQLRNVIQAVLTKAIIQGGTTLKDFTQPDGKPGYFAQVLQVYGRKGEECRECGTLIQAKVIGQRNSYFCPDCQPLPK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RL11_SHIB3
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: HTF1_PERAM
Sequence: QVNFSPNW
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor 1, Adipokinetic hormone 1, PerAm-AKH-1, Hypertrehalosaemic factor I, Neuropeptide M-I, PeA-CAH-I, Periplanetin CC-I.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEXA_RALSO
Sequence: MATLTTRQQQIYDLIHQTIQRTGFPPTRAEIAAEFGFSSPNAAEEHLRALARKGVIELTPGASRGIRLRAEGGASPHQFSLPSMGLMQLTLPLVGRVAAGSPILAAEHIDRQYQVDPSLFSSRPDFLLKVRGMSMRDAGILDGDLLAVQRAAEAANGKIVVARLGDDVTVKRFQRKGRQVELIAENPDFEPIHVDLDRDEFQLEGLAVGLIRPAAP
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: Y1118_ARCFU
Sequence: MKKLLVASLALLILTPVALAEDFSMDAEQLAVVLLKNTISNLEMSNKFVEILDNSGSDSVYQNLWGVIYGALAVMAVNNEVTTALLDEVSKSQELSSKVGDAINSLGENSTVVFGDVNGSKGLTLILRKESEVLQNGSYPYSDNETLSEAYARVVAEFTSRSVDFIVKLFSKIDEAWV
What are the official names of this protein?
Uncharacterized protein AF_1118.
Protein: EX7L_ECOLU
Sequence: MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSAQQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLWLARQQTMLERLQKRMSFALENQLKRAGQQQQRLTQRLNQQNPQPRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTSAADGAVLKQVKQVKAGDTLTTRLGDGVVISEVSAVTKTRKPRKKAANP
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_CHODI
Sequence: MPSTYINILLAFTMALLGLLLYRSHMMSSLLCLEGLMLALFILSTLMALNTHHTLSAVLPIVLMVFAACEAALGLALLVMVSNTYGLDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FTHS_STRSY
Sequence: MKTDIDIAQSITLKPITEIVEKVGISFDDIELYGKYKAKLSFDKINAVKDNAPGKLILVTAINPTPAGEGKSTITIGLADALSKIGKKTMIALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHIHQGNVIGIDQRRIIWKRVVDLNDRALRKVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDINDLKERLANIVIGYRFDCSPVYVRDLAVEGALTLILKDAIKPNLVQTIYGTPAFVHGGPFANIAHGCNSVLATTTALRLADYTVTEAGFGADLGAEKFLDIKVPNLPKAPDAVVIVATLRALKMHGGVAKTELSAENVEAVKAGFSNLKRHVENIRKYGIPAVVAINEFVSDTAAEIAVLKELCAAIGVPVELASVWANGADGGVELAETVVATIDNQAASYQRLYKSEDSLEEKVTKIVTQIYGGTGVVFEKKARNQLTEFAKNGWDKLPVCMAKTQYSFSDDQFALGAPTDFDITVREFVPKLGAGFIVALTGDVMTMPGLPKAPVALNMDVAADGTAIGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: EMP24_SCHPO
Sequence: MAFFNVFKAVLCAYFISVVFGHGITLKPHQRECFYENLRNNDQMSVTYQTNVGGDQLVSMSIYNPAGQIMHQEVPNSMAQYSFTVKNPGKYMYCFYNDALDGESKEVLFNVHGVIYISDEDLDANNPLLGKVRQLHDTISKVKHEQEYFVARERIHRNTAESTNDRVKWWSILQTVILVSVCVFQIFYLKRLFEVKRVV
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi (By similarity).
What are the official names of this protein?
Endosomal protein P24B.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Protein: DPO3B_MICLU
Sequence: MKFTVERDILTDAVSWAARSLSPRPPVPVLSGLLITAEAGVVSIASFDYETSARLEIEADVETAGQVLVSGRLLNDIVRSLPQAQVTVELDGGKVLVTCRSSRFSLATMPVGDYPALPELPAPAGTVDGAAFAHAVAQVTVAASKDDTLPILTAVKVEIEGDTITFLATDRYRLAMKEIRWTPADPSISTSLLIKARTLTEVAKSLGSGGDLEILLGQTADLVGFASGGRRTTSVLVDGEYPKIRSLFPESSPIQAVVDTAALVEASRRVALVAERNTALRMVFTEGQVTLDAGTGDDASANESVPCTLE
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN_SYNWW
Sequence: MIEISNLTKIYGSGPQEVMALKEVSLSIRKGEIFGIIGLSGAGKSTLIRCINMLERPTQGTIMVDGQDVGSLNSLELRRLRQKIGMIFQHFNLLSSRTVFENVMFPLEIAAVPKNEAAQKVNALLELVGLTDKAQVYPEQLSGGQKQRVGIARALANDPKVLLSDEATSALDPQTTRSILGLLKDINRKLGLTIVLITHDMNVIKDACDRVAVIDDSTIVEVGDVLNTFSNPGTPTSRSFINSIINREIPAEILHRQVIDHGSNSSRLIRVSFIGPSAGEPIISSMVQKYAIAANILYGNIDQVKDIPFGNLTLELIGPVNTINEALDFLRKCGLEIEVLNHAGN
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: IACH_PESFW
Sequence: MVSLKACVVAYGFTLLPALVSGSPLVPRYFQKHLVSRCNISAITVQSELGPQLSNTSLIFGPDNVLFPNATERWNTLDTPDVQLVVQPAAESDISKIVKYCNDNSIEFLVRNRGHGTTTSLSAFSGIEINVELLQGITIQPDGETAIFQAGTYGAEVINTLWDQGYVTTTGSTACVGLTGPSLGGGHSRYEGLYGLVMDNIVHYNIVLANGTEIGVNETSHPDLMWALKGAGHNFAIVTSLEKKIYPGENWHQHTYTWTQDKLETVFEALNTFHKSYNGTTPPKMGVNYGAIIMNTSYSTTEAVMEWGFQYAGPGDEAEALLAPFNAIGAIAEDQFDASYPTIAGTTSETCGSAKRAISSAMTLDYNITTERALYDHFVAKVAEYPDLAATAYLWHEGYSTEGYQIIPEDSTAYPHREENHLMVFFTEVPEDSDLLEPALDWAKEAMDLWNGGQPDRLPSTYVNYAQGADYETLESVYGYESWRLERLRSLKAEYDPENRFRYFVPIISDEA
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of iso-A82775C, a enylepoxycyclohexane and biosynthetic precursor of the chloropestolide anticancer natural products (PubMed:29384350).  Within the cluster, the prenyltransferase iacE prenylates siccayne to generate pestalodiol E, using dimethylallyl diphosphate (DMAPP) as cosubstrate (PubMed:29384350).  The probable oxidoreductase iacF is then involved in the epoxidation of pestalodiol F to pestalodiol F, which is further converted to pestalofone A by the short-chain dehydrogenase/reductase iacG (PubMed:29384350).  Iso-A82775C is subsequently generated from pestalofone A by the short-chain dehydrogenase/reductase iacC (PubMed:29384350).  Iso-A82775C is further condensed with maldoxin via a Diels-Alder reaction to produce the anticancer natural products chloropestolides A to E (Probable).
What are the official names of this protein?
FAD-linked oxidoreductase iacH, Iso-A82775C biosynthesis cluster protein HK.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: STRA_STRGR
Sequence: MSSSDHIHVPDGLAESYSRSGGEEGRAWIAGLPALVARCVDRWELKRDGGVRSGEASLVVPVLRADGTRAALKLQMPREETTAALIGLRAWGGDGMVRLLDHDEESSTMLLERLDGSRTLASVEDDDEAMGVLAGLLNRLHSVPAPPGLRGLGEIAGAMVEEVPSAVDSLADPEDRSRLRGWASAVAELVGEPGDRVLHWDLHYENVLAAEREPWLAIDPEPLVGDPGFDLWPALDTGWERIEATGDARRVVRRRFDLLTESLELDRGRAAGWTLARLLQNTLWDIEDGLTAIAPSQIAVAEALAKP
What is the function of this protein?
The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation.
What are the official names of this protein?
Streptomycin 6-kinase, APH(6), Streptidine kinase, Streptomycin 6-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the aminoglycoside phosphotransferase family.
Protein: SDS3_PONAB
Sequence: MSAAGLLAPAPAQAGAPPAPEYYPEEDEELESAEEDERSCRGRESDEDTEDASETDLAKHDEEDYVEMKEQMYQDKLASLKRQLQQLQEGTLQEYQKRMKKLDQQYKERIRNAELFLQLETEQVERNYIKEKKAAVKEFEDKKVELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLRTLNKLKSPKRPASPSSPEHLPATPAESPAQRFEARIEDGKLYYDKRWYHKSQAIYLESKDNQKLSCVISSVGANEIWVRKTSDSTKMRIYLGQLQRGLFVIRRRSAA
What is the function of this protein?
Regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1.  May have a potential role in tumor suppressor pathways through regulation of apoptosis.  May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity).
What are the official names of this protein?
Sin3 histone deacetylase corepressor complex component SDS3, Suppressor of defective silencing 3 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SDS3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIPA_MYCUA
Sequence: MNVAPEPGAAGAAAPQGRKLLRLEVRNAQTPIERKPPWIRTRARMGPEYTELKNLVRREGLHTVCEEAGCPNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAPLDRDEPRRVAESVHTMGLRYATVTGVARDDLPDGGAWLYAETVRAIKELNPSTGVELLIPDFNGKADQLGEVFEARPEVLAHNVETVPRVFKRIRPAFTYQRSLDVLTAARQFGLVTKSNLILGMGETPEEVRTALVDLHDAGCDIITITQYLRPSPRHHPVERWVRPEEFVEFAQYAEGLGFAGVLAGPLVRSSYRAGRLYEQARSRNTSGASNSG
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_CAMJE
Sequence: MKTQMNYAKEGIFTKEMQIVAQKENLSKDFLLENIACGKIIIPANINHKSLDPNGIGFGLRTKVNVNLGVSNDCVDYSEEMKKVELAHKFGIEAIMDLSNYGKTSRFRDELVNVSKAMIGTVPVYDAVGFLEKDLKQINAKDFLDVVYHHAKSGVDFMTIHAGINSRAAHIFKQSKRLTNIVSRGGSVLYAWMMMKDAENPFFEYYDDLLDICLKYDVTLSLGDALRPGSTHDASDGAQISELIELSLLTQRAWDVGIQVMIEGPGHMAINEIEANMQLEKRLCKGAPFYVLGPLVTDIGAGYDHISGAIGGAVAAASGADMLCYVTPAEHLRLPNLEDVREGIVATKIAAHAGDIAKLPKERARDDEMSKARQEIDWEKMFKLAIDGEKAKKMFNERRPDDLNSCSMCGKMCAMNTMNQILKGEDVSLA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: Y956_METJA
Sequence: MHEDVWSLIKETNHKTILYSHGMKNRVLLGYLLKLRGKYNFDFEAVTFISDRSPKWVREEIKWIMKANDVKHRFIECGKCKISLENNGHDYHGSCVVWEGIKNFEGGVVASSIGEHIKDKERFLTWCNDYNLFPPFIHLNVSRERLVKEFESLDKNLISSCYHACVFCPILYKLGKSLIKSEIFYKKKILTDNERKEHALNEFYDAMKEQDIGRMINSVKIYYNKYIRELDEPYADYIKSRDVEMFDKLVNKCKEYLGVK
What are the official names of this protein?
Uncharacterized protein MJ0956.
Protein: UREF_METPB
Sequence: MIDALRLMAWLSPTYPVGAFAYSHGLEWAVECGDVRDAATLADWLSDVLERGAGRNDMILCACAHRAVAARDDADLVAINDLALALAPSRELHLETSQQGRSFLDATLQAWPCPALAEVAARLEGRLAYPIAVGAAAGAHGVAREATVAAYGLAFVQNLVSAALRVAPVGQSAGTAVLASLTPRVAALAETLHAADRDALGSATLRLDLGSFRHETQYSRIFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP167_BPPH2
Sequence: MEAILMIGVLALCVIFLLSGRNNKKKQEARELEDYLEDLNKRVVQRTQILSELNEVISNRSIDKTVNLSACEVAVLDLYEQSNIRIPSDIIEDLVNQRLQSEQEVLNYIETQRTYWKLENQKKLYRGSLK
What is the function of this protein?
Binds to the long stretches of ssDNA of the viral DNA replication intermediates created during the protein-primed mechanism of replication of the viral genome and attaches the viral DNA to the membrane of the infected cells (PubMed:11741949) (PubMed:11169113).  Required for the redistribution of replicating viral DNA from the initial replication site to membrane-associated sites surrounding the nucleoid (PubMed:10921898).  Required for the second pull step of DNA ejection (PubMed:17526715).
What are the official names of this protein?
DNA replication protein 16.7, Gene product 16.7, gp16.7, Protein p16.7.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus gp16.7 family.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass membrane protein.
Protein: PYRDB_MARSD
Sequence: MDVSIDFAGLKLKNPILTASGTFGFGLEFQRYGDLESLGGIVVKGLSLKPREGNPMPRIAETPCGMLNAIGIQNPGVEEFINKKLPKLPWKTLPVLANLYATDAEEFGELAGVLAGEEGVAALEVNVSCPNVKEGGIAFGQDPKQITKVAEAVKKNAGNKPIIIKLSPNVTDITVCAKAAEDGGADALSLINTLSGMAVDIERRTPRLANVIGGLSGPAVKPVALRCVYQTVNAVKIPVMGLGGITTAEDAAEFLLVGAKAVQIGTGNFLSPDTAFRIAEELPKVLERVKAESLDEFIGSLKLPK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.