PharMolix/UniProtQA huggingface dataset:
Protein: RAD26_YEAST
Sequence: MEDKEQQDNAKLENNESLKDLGVNVLSQSSLEEKIANDVTNFSNLQSLQQEETRLERSKTALQRYVNKKNHLTRKLNNTTRISVKQNLRDQIKNLQSDDIERVLKDIDDIQSRIKELKEQVDQGAENKGSKEGLQRPGETEKEFLIRTGKITAFGHKAGFSLDTANREYAKNDEQKDEDFEMATEQMVENLTDEDDNLSDQDYQMSGKESEDDEEEENDDKILKELEDLRFRGQPGEAKDDGDELYYQERLKKWVKQRSCGSQRSSDLPEWRRPHPNIPDAKLNSQFKIPGEIYSLLFNYQKTCVQWLYELYQQNCGGIIGDEMGLGKTIQVIAFIAALHHSGLLTGPVLIVCPATVMKQWCNEFQHWWPPLRTVILHSMGSGMASDQKFKMDENDLENLIMNSKPSDFSYEDWKNSTRTKKALESSYHLDKLIDKVVTDGHILITTYVGLRIHSDKLLKVKWQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNLTELWSLFDFIFPGKLGTLPVFQQQFVIPINIGGYANATNIQVQTGYKCAVALRDLISPYLLRRVKADVAKDLPQKKEMVLFCKLTKYQRSKYLEFLHSSDLNQIQNGKRNVLFGIDILRKICNHPDLLDRDTKRHNPDYGDPKRSGKMQVVKQLLLLWHKQGYKALLFTQSRQMLDILEEFISTKDPDLSHLNYLRMDGTTNIKGRQSLVDRFNNESFDVFLLTTRVGGLGVNLTGANRIIIFDPDWNPSTDMQARERAWRIGQKREVSIYRLMVGGSIEEKIYHRQIFKQFLTNRILTDPKQKRFFKIHELHDLFSLGGENGYSTEELNEEVQKHTENLKNSKSEESDDFEQLVNLSGVSKLESFYNGKEKKENSKTEDDRLIEGLLGGESNLETVMSHDSVVNSHAGSSSSNIITKEASRVAIEAVNALRKSRKKITKQYEIGTPTWTGRFGKAGKIRKRDPLKNKLTGSAAILGNITKSQKEASKEARQENYDDGITFARSKEINSNTKTLENIRAYLQKQNNFFSSSVSILNSIGVSLSDKEDVIKVRALLKTIAQFDKERKGWVLDEEFRNNNAS
What is the function of this protein?
May be involved in the preferential repair of active genes.
What are the official names of this protein?
DNA repair and recombination protein RAD26, ATP-dependent helicase RAD26.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CDPKI_ORYSJ
Sequence: MGLCSSSSARRDAGTPGGGNGAGNKDNAGRKGIVACGKRTDFGYDKDFEARYALGKLLGHGQFGYTFAAVDRRSSERVAVKRIDKNKMVLPVAVEDVKREVKILKALQGHENVVHFYNAFEDDNYVYIVMELCEGGELLDRILAKKDSRYSEKDAAVVVRQMLKVAAECHLHGLVHRDMKPENFLFKSTKEDSSLKATDFGLSDFIRPGKHFRDIVGSAYYVAPEVLKRKSGPESDVWSIGVITYILLCGRRPFWDKTEDGIFKEVLKNKPDFRRKPWPNITPCAKDFVQKLLVKDPRARLTAAQALSHEWVREGGQASDIPLDISVLHNMRQFVKYSRFKQFALRALASTLNAEELSDLRDQFNAIDVDKNGTISLEELKQALAKDVPWRLKGPRVLEIVEAIDSNTDGLVDFEEFVAATLHVHQLVEHDTEKWKSLSQAAFDKFDVDGDGYITSDELRMQTGLKGSIDPLLEEADIDRDGKISLDEFRRLLKTASMSSRNVQTPRSVHRS
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity).  Functions upstream of MPK5 in a signaling pathway that represses defense gene expression and negatively regulates resistance to rice blast fungus.  Phosphorylates MPK5 at Thr-14 and Thr-32 and activates MPK5 independently of MAP kinase kinase (MKK) phosphorylation (PubMed:25035404).  May be involved in arbuscular mycorrhizal presymbiotic phase signaling (PubMed:21595879).  Phosphorylates the elicitor-responsive protein ERG1 in vitro.  Phosphorylation is calcium-dependent (PubMed:23456295).
What are the official names of this protein?
Calcium-dependent protein kinase 18, OsCDPK18, OsCPK18, OsCDPK5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: IF1_PASMU
Sequence: MAKEDCIEMQGTILETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTIEMTPYDLNKGRIIFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_FRASN
Sequence: MDTAEIRRRFLNHFSERGHTVVPSASLVAQDPTLLLVNAGMVPFKPYFLGDLKAPWNRATSVQKCVRTVDIDNVGRTARHASFFQMCGNFSFGDYFKAEAIPFAFELIVDGYGFNPDDLWATVYLDDDEAEAIWRTLLPAERIQRRGKKDNFWSMGVPGPCGPCSEIYFDRGPAYGREGGPEADEDRYLEIWNLVFMQFARGEGSEYGYEIVGDLPARNIDTGMGLERMATILQGVENLYEIDISRPVLDAAGRLTGTRYGADPDSDVRLRVVADHTRTAAMLISDGVSPSNEGRGYVLRRMLRRAVRDARLLGAREPVMDELFGVVRAAMGPIYPELVDQAEAITAVAVAEETAFLETLRTGTTLFDTAVTQARSSGSSQLSGESAFRLHDTYGFPIDLTMDMAADAGLTVDEAGFRRLMERQRQAAKADRASRRIGNLDLSAFRPILAASGPTTFTGYTELGRESGIVGIVGIGDGDSLTAAGEGEEVGILLDATPFYAESGGQEADLGRIRFDGGEAEVLDVQRPVPDLVMHRVKVLGGELRVGADVFAEVDVERRRAVSRSHTATHLVHTAFRRALGESATQAGSLNSPGRLRFDFHALGAVPDSVLADVEDEVNEIALRDLEVRWYVTSQEEARRLGAMALFGEKYGDRVRVVDVGDYARELCGGTHVASSAQLGAIKLLSESSISAGTRRVEALVGMDAFRFLAREHVLVSQLSSTLKARPDELADRVADIVGRLRDAEKELERLRAQAVLAGSAALAAGAEDVGGVALVTAQVPAGTPADDVRLLALDVRGRLAGRPAVVAVVEAAGAAVVVATDETARTRGLRAGDLVRHSWAALGGKGGGKPDVAQGGRGDADMIPKVFARLRELVADQSA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_LACGA
Sequence: MARIAGVDLPRNKRVVVALTYIYGIGEPTAKKICKDAGISEDIRTNDLTPEDQEKLRSEVDKYRVEGDLRREVSLNIKRLVEIGSYRGIRHRRGLPVRGQNTKNNARTRKGSKRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GLMM_STRSY
Sequence: MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETDVPRVFVARDTRISGQMLEAALIAGLLSVGIHVYKLGVLATPGVAHLVKTEKASAGVMISASHNPAQDNGIKFFAGDGFKLDDALEAEIEALLDAEEDTLPRPSAQGLGDVVEYPEGLRKYQQFLVSTGTDLDGMKVALDTANGAAATSARQIFVDLGADLTVMAEKPDGLNINEGVGSTHPEKLQELVKETGSQIGLAFDGDSDRLIAVDENGVLVDGDRIMYIVGKYLADRGLLAKNTIVTTVMSNLGFHKALDREGIEKAVTAVGDRYVVEEMRKEGYNVGGEQSGHVILMDYNTTGDGQLTAVQLTKIMKETGKKLSELAAEVTIYPQKLVNIRVENSMKDKAMEVPAIAAIIEKMEAEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRAEIGS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: KUP_SHIF8
Sequence: MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGLERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIALGAVVLSITGGEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NEDD8_CAEEL
Sequence: MLIKVKTLTGKEIELDIEPNDRVERIKEKVEEKEGIPPPQQRLIFAGKQMNDDKTAADYKVLGGSVLHLVLALRGGF
What is the function of this protein?
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis.  Covalent attachment to its substrates requires prior activation by the E1 complex uba-3-ula-1 and linkage to the E2 enzyme ubc-12.  Attachment of ned-8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
What are the official names of this protein?
NEDD8, Neddylin, Protein NED-8, Ubiquitin-like protein Nedd8.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear during interphase, also cytoplasmic during interphase and mitosis.
Protein: NORB_STAA1
Sequence: MEKPSREAFEGNNKLLIGIVLSVITFWLFAQSLVNVVPILEDSFNTDIGTVNIAVSITALFSGMFVVGAGGLADKYGRIKLTNIGIILNILGSLLIIISNIPLLLIIGRLIQGLSAACIMPATLSIIKSYYIGKDRQRALSYWSIGSWGGSGVCSFFGGAVATLLGWRWIFILSIIISLIALFLIKGTPETKSKSISLNKFDIKGLVLLVIMLLTLNILITKGSELGVTSLLFITLLAIAIGSFSLFIVLEKRATNPLIDFKLFKNKAYTGATASNFLLNGVAGTLIVANTFVQRGLGYSSLQAGSLSITYLVMVLIMIRVGEKLLQTLGCKKPMLIGTGVLIVGECLISLTFLPEILYVICCIIGYLFFGLGLGIYATPSTDTAIANAPLEKVGVAAGIYKMASALGGAFGVALSGAVYAIVSNMTNIYTGAMIALWLNAGMGILSFVIILLLVPKQNDTQL
What is the function of this protein?
Multidrug efflux pump that acts independently of NorA and is one of the factors that confers resistance against diverse quinolones and chemical compounds.
What are the official names of this protein?
Quinolone resistance protein NorB.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UP01_EPHDI
Sequence: NPVLPCPVGSLYK
What are the official names of this protein?
Unknown protein 1.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RCC2_HUMAN
Sequence: MPRKKAAAAAWEEPSSGNGTARAGPRKRGGPAGRKRERPERCSSSSGGGSSGDEDGLELDGAPGGGKRAARPATAGKAGGAAVVITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIGRKEVPKQQAAYRNLGQNLWGPHRYGCLAGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGPSPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESETEKEKIKKLPEYNPRTL
What is the function of this protein?
Multifunctional protein that may affect its functions by regulating the activity of small GTPases, such as RAC1 and RALA (PubMed:12919680, PubMed:25074804, PubMed:26158537, PubMed:28869598).  Required for normal progress through the cell cycle, both during interphase and during mitosis (PubMed:23388455, PubMed:12919680, PubMed:26158537).  Required for the presence of normal levels of MAD2L1, AURKB and BIRC5 on inner centromeres during mitosis, and for normal attachment of kinetochores to mitotic spindles (PubMed:12919680, PubMed:26158537).  Required for normal organization of the microtubule cytoskeleton in interphase cells (PubMed:23388455).  Functions as guanine nucleotide exchange factor (GEF) for RALA (PubMed:26158537).  Interferes with the activation of RAC1 by guanine nucleotide exchange factors (PubMed:25074804).  Prevents accumulation of active, GTP-bound RAC1, and suppresses RAC1-mediated reorganization of the actin cytoskeleton and formation of membrane protrusions (PubMed:25074804, PubMed:28869598).  Required for normal cellular responses to contacts with the extracellular matrix of adjacent cells, and for directional cell migration in response to a fibronectin gradient (in vitro) (PubMed:25074804, PubMed:28869598).
What are the official names of this protein?
Protein RCC2, RCC1-like protein TD-60, Telophase disk protein of 60 kDa.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus. Cytoplasm, cytoskeleton. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Chromosome. Midbody. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Appears in the nucleus at G2, then concentrates at the inner centromere region of chromosomes during prophase. Redistributes to the midzone of the mitotic spindle during anaphase. Here, the protein covers the entire equatorial diameter from cortex to cortex (PubMed:12919680, PubMed:1939370, PubMed:7559776, PubMed:9914378). Colocalizes with cytoplasmic microtubules in interphase cells (PubMed:23388455). Colocalizes with RAC1 at the cell membrane (PubMed:25074804).
Protein: MNMG_ERYLH
Sequence: MGRAMHDFDILVVGGGHAGVEAACAAARMGVRTALVSFDPARIGAMSCNPAIGGLGKGHLVREVDAFDGVIARAADAAAIHYRMLNRSKGSAVWGPRVQADRKLFHAAVQAIVATQENLTVVPGEVAALRFEGARVTGIELADGTALSGQAVILCTGTFLGGKLYRGEEIMVGGRIGEDSASRLAEQMYGLELPMARLKTGTPPRLDGRTIDWAALEEQPSDGEDWTLSALTPARSNPEIFCGITRTNARAHDIIRANLNRSPLFSGAIDAQGPRYCPSIEDKIHRFGDRDGHQVFLEPEGLDTHLVYPNGISTSLPVDVQLGMLRAMDGLFHVELVEPGYAVEYDHIEPRALTSGLRLKDVEGLYCAGQINGTTGYEEAAAQGLIAGLNAACVVLDREAPALDRATSYMAVMVDDLTLHGVSEPYRMLTARAEYRLRLRANNATARLTPLAIELGCVGGERAEWFARREEKRARLDAALDSQASAKQMQDLGLPVKSDSGKMALREWLRFPTIDFPDLAPLVPEVDTGTELAAELAEDAAYAPYLARQDAELRELKANEAITLAADFPFAEVPGLSSEMVERLTAARPETLAAAGRVPGVTPAALAAVLVHTRKRGRAAA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3408_METJA
Sequence: MDKYVNGSINNIQNNNVLEYTINEINQYPEDVLEVAIKLLNIRYDPNTIKELDEHNKNNTEILGNIWLFSLNKLPLKERQLLLKYGLWELGAELPTDKLYRLEDAITSILGWSFWEIHDPKEVVLKLVKAGEMLHQQNRDIKIGEIVGEEFTALHQQNNDFTMLHQCGEEFTALHQQNNDFTMLHQLLHNIQDNSMIEDLCNKIGERANTLKKSYKNDDCKKTAKIFTILTFEGMRFDEFMNKAIEQLKIGEGTLKQHLKIYKQLEWIDIRKNPEDYDRKYIYLTYKFYEDIKDILDEYLPKKAFQEAEAKSEFMEDLKKSLKKFIEERLTPEGFEFDINEVDRLKGKERIVGAYFRSLLLNEPYEAIEMIYKVYYEKYFQFKPLEINIIGLETLRSRTIMTKAKDWGEFRNKLCVFRGDIAGIIHHRKSRPILRRYVCIDLDKNGNNKGCNCEVIRLYEPVENSQDYKIKCPECGRDIKYSESLFKDEDGEPIKLERDLTIAIIQLKETDEVYRVYLPYTPEINNLRDVEIVGILKTNHKGEYYIEGLSINPQKTINFNYDAFVRKVKNAGYSNALDYIKDRVFYEVKAILDKEGKNPTIDTLITLEILASSHIYWDKNRDGHLKPETIDCLFIGSYGQGKSLTIEPLAKLHNTTEDMIRVDMPNIENLIGLVISRDNIKFYKKGIIPMNHNRPIFIEEMMDFILRVGNDLDLLKSGKTSGIWKREREGYNIPMIGVSPWIGVGNIKDIDLMELWEIYHLKGFEEFKEAMINYFAKKLLKQHDYDRNEAEDRAKKIVNNILGANPQLNASEWLLSKILDFTLKNLRGMTDRIPLIYLLKPYTNEDWKEIKLHTYKVKRLREDNNFIKQKNLEAYECALFISYIKNKDIEFKEDALKTLWEVEEKLRDLLRDYGLFKGYSDRLFNQIEYMAKAYAKLKFKEYVDLEDVRDALKIWFKTILGVLLRIKAPDKVKEIFKLVGEEIKETQQKDEELEEINKLIEESRKLSQLKREILNYMLQNPKIYTTVEIAENFNISEDTARGILKELWKNGDVDNPESDQWRPL
What are the official names of this protein?
Uncharacterized protein MJECS08.
Protein: YBOH_SCHPO
Sequence: MLFNNFLCFAVSAIPLVSAMPLGNAPYHHHHHAGLNASNITVGVNVTNTTAFSKRDGGFPDGVYDCSSFPDDQNGVVRLDYLGFGGWSGVQKNDGKYGTASTCQDNTYCSYACKPGMSKTQWPSEQPDNGVSVGGLYCKNGKLYLTQKDNSNLCEDGKGTAYVKNTLSSNVAICRTDYPGTENMNIPTNIDGGSKQPLSDVDEDSYYNWGGKKTSAQYYVNKSGRSAEDVCVWGNEGDDYGNWAPMNFGSGYTDGKTWLSMSFNPLSSAKLDYNIRIKSDGGSLSGDCYYEDGSFHGSTADSSGCTVSVTGGNAYFELY
What is the function of this protein?
Cell surface beta-glucosidase involved in cell wall biogenesis.
What are the official names of this protein?
Probable secreted beta-glucosidase C2G2.17c.
What is the protein family that this protein belongs to?
Belongs to the SUN family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPVIF_BACSU
Sequence: MDNQFFKNIEKKTGVKMQDVMNLAGSLQNANFKDENTVRSVINRVAQMANRRVPKELEDKIVESITSGKEKLDFGTISKMMDNK
What is the function of this protein?
Transcription factor involved in spore coat assembly and spore resistance.  Regulates the transcription of at least cgeA, cotG and cotS.
What are the official names of this protein?
Sporulation-specific transcription factor SpoVIF, Stage VI sporulation protein F.
What are the subcellular locations of this protein?
Cytoplasm. Note=localizes in the mother cell compartment during spore development.
Protein: LF1_EBVB9
Sequence: MALQTDTQAWRVEIGTRGLMFSNCVPLHLPEGQYHKLRLPVSAYEALAVARYGLVGSLWEVPAVNSALQCLAAAAPCKDVKIYPSCIFQVHAPMFVTIKTSLRCLNPHDLCLCLICVGAAILDIPLLCAPRDGAGARAAEGQAAAAQGGKLRVWGRLSPSSPTSLSLAFPYAGPPPVAWYRHSINLTRSEGVGIGKDCAQDHACPVPPQGHASSAADQAGVPERGRKRAHEGPGAGEAASAGRGDVALSQSRALLWRGLGWDTGRGRLAPGLAMSRDAASGSVHLDIQVDRAEEGWVCDVLLEPGPPTAREGCSLSMDPGLVTLKDAWTLFPLHPEHDAVVPPKEEIHVMAQGHLQGGTPSLWGFTFQEAACDQWVLRPRVWTAHSPIKMTVYNCGHKPLHIGPSTRLGLALFWPAERSDNLDAGRIFYQLTSGELYWGRTVARPPTLTLPVDELRPWPKLTPEEPMQH
What are the official names of this protein?
Uncharacterized LF1 protein.
What is the protein family that this protein belongs to?
Belongs to the epstein-barr virus LF1 family.
Protein: SPT16_CAEEL
Sequence: MSGKRAVLNKDLFFQRAERLYEHWEKGADGLDSIKSLAFVYGETDNPYTKTSALFTWLFGHEIADTVLLLLKDHIYILGSNRKVEFFGSVTGDNQSSGKVPTVSTLLRDKTDKDAGNFEKLIDHIKSAGGDVGNFVKEKFSSEFVSSWNKALEEGGVNKNDVTLAFTHLFAVKDDKEMDLIRKSAQATTASWTAARARYVEIIDQEKRVRHSVLSNEFAAFMKDSKVQQALAKYEADTCYDPIVMSGGNYSFKWNHESSESHLHSQFGTIITSFGARLSEYCTNLTRTMLIFPSSELETAYEAILAAELAVIAALKPGAKLSDVYKIGIDTLTEKSPKLAETLNKKELGFATGIEFRESRLAISAKCDEVVKAGMVFIVYIGVDSIPNKNKGEKGKPAAIAISDTILVKEEGDNEILTEKAKSRLKSNVIKFKEEQENREAEKDNDQKKMLGRGQRSVVLTDQTRNKTTNEELRKERQKELGVQLNELAKARLSKQGGGTDEKKSKKSNVSYKTEERFPQDADVQKMLIFVDRKYDSVVVPIFGIPVPFHISMIKNCSQSVEGDFTYLRINFATPGSQVGKDSGQFPHPLAHYMKELTFRASNIKDHHSDSTAPSHNLSTAFRLIKEMQKRFKTEEAEEREKEGAVKQDKLILSQNKLNPKLKDLLIRPNIIQKRITGSLEAHTNGFRYTSLRGDRIDVLYNNIKHAFFQPCDNEMIILLHFHLKNPVLWGKKKYKDVQFYTEVGEITTDLGKYHHMQDRDDMQSEQQEREMRRRLNAAFNSFCEKVSRLTNDQFEFDSPFAGLGFFGVPYRSATTLKPTASCLVNLTEWPTFIVTLSEVELVHFERVSLQLKNFDMVFIFKDYKIKPQMVAQIPMSSIDKIKEWLHTCDIWYSEGIQSLNWAKVMKTITDDLEAFFEEGGWSFLNVESDNEEAMDDSDDSDAYDPEEEDASAGSGSESDEDESEGEETESDDDDEGSLDSDESEGKDWSDLEEEAANADKRREVEEPSRDRDRKRPHSSKSGPSHKRRK
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).  In embryos, promotes cell cycle progression and chromosomal segregation (PubMed:25446273, PubMed:30336114).  Plays a role in the development of the anterior pharynx during embryonic development (PubMed:30336114).
What are the official names of this protein?
FACT complex subunit spt-16, Facilitates chromatin transcription complex subunit spt-16.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. SPT16 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ILVC_CAMJR
Sequence: MAITVYYDKDCDLNLIKSKKVAIIGFGSQGHAHAMNLRDNGVNVTIGLREGSVSAVKAKNAGFEVMSVSEASKIADVIMILAPDEIQADIFNVEIKPNLSEGKAIAFAHGFNIHYGQIVVPKGVDVIMIAPKAPGHTVRNEFTLGGGTPCLIAIHQDESKNAKNLALSYASAIGGGRTGIIETTFKAETETDLFGEQAVLCGGLSALIQAGFETLVEAGYEPEMAYFECLHEMKLIVDLIYQGGIADMRYSISNTAEYGDYITGPKIITEETKKAMKGVLKDIQNGVFAKDFILERRAGFARMHAERKNMNDSLIEKTGRNLRAMMPWISAKKLVDKDKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: HN_NDVTG
Sequence: MDRAVSQVALENDEREAKNTWRLIFRIAILLLTVVTLATSVASLVYSMGASTPSDLVGIPTRISRAEEKITSALGSNQDVVDRIYKQVALESPLALLNTETTIMNAITSLSYQINGAANNSGWGAPIHDPDFIGGIGKELIVDDASDVTSFYPSAFQEHHNFIPAPTTGSGCIRIPSFDMSATHYCYTHNIISSGCRDHSHSYQYLALGVLRTSATGRIFFSTLRSINLDDTQNRKSCSVSATPLGCDMLCSKVTETEEEDYNSAVPTLMVHGRLGFDGQYHEKDLDVTTLFEDWVANYPGVGGGSFIDSRVWFSVYGGLKPNSPSDTVQEEKYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRIQQAILSIKVSTSLGEDPVLTVPPNTVTLMGAEGRILTVGTSHFLYQRGSSYFSPALLYPMTVSNKTATLHSPYTFNAFTRPGSIPCQASARCPNSCVTGVYTDPYPLIFYRNHTLRGVFGTMLDGEQARLNPASAVFDSTSRSRITRVSSSSTKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKNDGVREARSG
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: SYDP_SALG2
Sequence: MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISSTRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQTWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGTRNRTVLAATLAEFLTQLNPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: YHFL_ECOL6
Sequence: MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISISKIIGGCGPTAQ
What are the official names of this protein?
Uncharacterized protein YhfL.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DTD_OCEIH
Sequence: MKVVIQRSKEASVTVDDQIIGNISSGFVVLLGITHEDTYEDIQYLVSKIPNLRVFEDENGKMNLSLKDVGGSILSVSQFTLYGDTRKGRRPNFMQAAKPSVAEDLYNKFNTSLIDEGIHVETGEFGAMMDVKLTNDGPVTLIIDSKDR
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.