PharMolix/UniProtQA huggingface dataset:
Protein: WRI1_ARATH
Sequence: MKKRLTTSTCSSSPSSSVSSSTTTSSPIQSEAPRPKRAKRAKKSSPSGDKSHNPTSPASTRRSSIYRGVTRHRWTGRFEAHLWDKSSWNSIQNKKGKQVYLGAYDSEEAAAHTYDLAALKYWGPDTILNFPAETYTKELEEMQRVTKEEYLASLRRQSSGFSRGVSKYRGVARHHHNGRWEARIGRVFGNKYLYLGTYNTQEEAAAAYDMAAIEYRGANAVTNFDISNYIDRLKKKGVFPFPVNQANHQEGILVEAKQEVETREAKEEPREEVKQQYVEEPPQEEEEKEEEKAEQQEAEIVGYSEEAAVVNCCIDSSTIMEMDRCGDNNELAWNFCMMDTGFSPFLTDQNLANENPIEYPELFNELAFEDNIDFMFDDGKHECLNLENLDCCVVGRESPPSSSSPLSCLSTDSASSTTTTTTSVSCNYLV
What is the function of this protein?
May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).  Transcriptional activator involved in the activation of a subset of sugar-responsive genes and the control of carbon flow from sucrose import to oil accumulation in developing seeds.  Binds to the GCC-box pathogenesis-related promoter element.  Promotes sugar uptake and seed oil accumulation by glycolysis.  Required for embryo development, seed germination and, indirectly, for seedling establishment.  Negative regulator of the ABA-mediated germination inhibition.
What are the official names of this protein?
Ethylene-responsive transcription factor WRI1, Protein ACTIVATOR OF SPORAMIN::LUC 1, Protein WRINKLED 1.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GP180_HUMAN
Sequence: MGGLRLLAVALTCCWWPQGSQGKTLRGSFSSTAAQDAQGQRIGHFEFHGDHALLCVRINNIAVAVGKEAKLYLFQAQEWLKLQQSSHGYSCSEKLSKAQLTMTMNQTEHNLTVSQIPSPQTWHVFYADKYTCQDDKENSQVEDIPFEMVLLNPDAEGNPFDHFSAGESGLHEFFFLLVLVYFVIACIYAQSLWQAIKKGGPMHMILKVLTTALLLQAGSALANYIHFSSYSKDGIGVPFMGSLAEFFDIASQIQMLYLLLSLCMGWTIVRMKKSQSRPLQWDSTPASTGIAVFIVMTQSVLLLWEQFEDISHHSYHSHHNLAGILLIVLRICLALSLGCGLYQIITVERSTLKREFYITFAKGCILWFLCHPVLACISVIFSDYQRDKVITIGVILCQSVSMVILYRLFLSHSLYWEVSSLSSVTLPLTISSGHKSRPHF
What are the official names of this protein?
Integral membrane protein GPR180, Intimal thickness-related receptor.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NEUR4_HUMAN
Sequence: MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGCCWPS
What is the function of this protein?
Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides.  Efficiently hydrolyzes gangliosides including alpha-(2->3)-sialylated GD1a and GM3 and alpha-(2->8)-sialylated GD3 (PubMed:15847605, PubMed:21521691, PubMed:15213228).  Hydrolyzes poly-alpha-(2->8)-sialylated neural cell adhesion molecule NCAM1 likely at growth cones, suppressing neurite outgrowth in hippocampal neurons (By similarity).  May desialylate sialyl Lewis A and X antigens at the cell surface, down-regulating these glycan epitopes recognized by SELE/E selectin in the initiation of cell adhesion and extravasation (PubMed:21521691).  Has sialidase activity toward mucin, fetuin and sialyllactose (PubMed:15847605).
What are the official names of this protein?
Sialidase-4, N-acetyl-alpha-neuraminidase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein. Cell projection, neuron projection. Note=Predominantly associates with endoplasmic reticulum membranes. Only a small fraction associates with mitochondrial and plasma membranes. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein. Lysosome lumen. Note=According to PubMed:15213228, isoform 2 is soluble, N-glycosylated and found in the lumen of lysosomes. However, no signal sequence nor N-glycosylation site is predicted from the sequence.
Protein: VE2_BPV5
Sequence: MAAAERLSAAQETQMTLLEKPSFDLKDHISYYGALRTENTIFYAARKKGLTSLGHCPVPTLATAAANAKAAIEMQLLLKDLLRSPFAKNDWSLNDVSHERYKAPPSDTLKRKPRIVEVIFDKDPQNKTWYTLWDEVYVCTVDGWTLTTSGADATGIFVNMQGSRQYYELFGEDAQRFGTSGTWEVIDQNQRFHFPPSSRADTTDGLPGLQEEPRGGDGPTCSGPAPAIPDSPSRCLSRGFAGRDPGCHRNRHRVHPYILSGGQRILVTSSSSSTVQGPLSSGSSQHSQSRGRPPSPDSTETERARTPVNSDRQRAGEFDLLKGGCRPCCLIEGNGNKVKCLRFRLKKSHRSRFLDITTTFWATGDEGSDRQGNGTILITFTDTTQRDLFLGSVSIPGELSVRRITISTD
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: OPGG_ECOL6
Sequence: MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATAVKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAYKFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPSAWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDEDKLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTSIGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MUTL_CHLT3
Sequence: MSLIKKLPDIVANKISAGEVVQRPASAVKELLENAIDAGADEITLAIKAAGKTLIQVIDNGCGLSEEDATLCFERFATSKISDVGDLENLHTLGFRGEALASIASVSQVELKTKRYDDRTGTLVKISGGRFEEVSRTETPNGTAFSIRNLFYNVPARRKFLKTNATEYKHIFETVQAQTLVYPDIKWRFYSDDEEIFSFLNNNLSERLDYFFGKDFSQNLIEFTEENDFMKLRGYLGKPAMMKRTKNQQFLFINNRVTQSKLLSSAIMTAYGELLGEREYPFFLIYMDIAPHYIDVNVHPTKMEVKFDDERNIYNMVHSVVKHRIKTLDFSPNVQVEEKPDSPRPTGESFNFPGVAKRLSYNDRDADMRSSNALFRDYKTYYKAQDERAEPGFFANPKREMDWRSSLPAHTEASLTPPKQAEPEGNPTFHDGSRQMEIFIQSRDDEPATAGQERFVWQLHNTYILTQIKSGLLIIDQHVAHERILYERAIAVMESNVPNSQQLLFPHSAKLSAWEFDVLKEIKTDLVQLGFSLRILDQRTVLVEGIPPDVMPGREERILHEMLEQYQDYQQNLKLEQRDNVAKSYACRSSIMAGQKLSRNEMTSLIDQLFATSMPYVCPHGRPIIIKLSIEELDKMFGRS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: TDH_SHEAM
Sequence: MKALAKLKPEEGIWMVDAPKPEMGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVRGFKIGDRVSGEGHITCGHCRNCRAGRTHLCRNTTGVGVNREGSFAEYLVIPAFNAFKIPDDISDDLAAIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVCRHVGARHVVITDVNEYRLELARKMGATRAVNVAKENLKDVMKDLGMTEGFDVGLEMSGVPAAFHAMLDTMNHGGKIAMLGIPGGEMAIDWSKVIFKGLIIKGIYGREMFETWYKMASLLQSGLDLSPIVTHHFKVDDFQQGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBAA_ANGAN
Sequence: MSLSAKDMAVVKGFWNKIAPKADEIGGEALGRMLRVFPQTKAYFAHWKDTSPNSPEVKKHGALILATIGDVVNRIENMTTVLGSLSDLHAFKLRVDPANFKILGHNIMVVICMTFPNDFTPEVHLSVDKFFQNFTLALSERYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin anodic subunit alpha, Hemoglobin anodic alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MURD_FRATW
Sequence: MFSFYFNDNKITKLLMVGYGSTGKSVCDFLANFIDITVDISQNDDEFVNYDLNSYDLITVSPGIPLNKSPYRALTKFKDKIVSDIDIFYQYIKDTKAKTIAVTGSNGKSTVVTMTDFVLKDLGYKSILVGNIGTPALNKIGEKFDYCVVEVSSFQINLFNCVRFDLGCIINVSPDHLDRYQNFEQYKQSKLNLAKFSNDFFVYDVHNGIKYAGEYQIIRGAIYRNSTKLLDIVETKLFGEHNLENIIVVLNILDRLGLDINQAIASIKKFKGLEHRCKIVKKVNGTTYINDSKGTNVGATIAALNSITNSKNIILLLGGVAKGGDFSLMIKSLDKYVKYVYIYGADKEYIESYIKGYCKYQLCNNMKQAFELASQKANSNEIVLLSPACASFDEFSGYAQRGEVFQNLVAQLEQKS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_EXISA
Sequence: MTKIMAVNAGSSSLKFQLLEMPTEELLAVGLVERVGKEDAIFTIKYGEGQKFNVVTPLHTHKEAVELTLEKLIELDIIQSFDEISGVGHRVLHGKELYADSVVIDDEVMKNIESFTELGPLHIPPNLTGIRAFQAILPNVPQVAVFDTAFHQSMPEENFLYSLPYEYYTEHGVRKYGFHGTSHKYVTQRAAELLGRPLEDLRLISCHLGSGASIAAVAGGRSIDTTMGFTPLEGITMGTRSGSLDPALIPFLMQKTGKSAEDVLNVMNKESGVYGLSGISSDLRDIEQAAAEGNHRAEVSLKIFSNRIHGYIGQYAAEMNGVDAIIFTAGVGENSDVIRERILRGLEFMGVYWDPSLNNGARGKELFINYPHSPVKVIIIPTNEELVIARDTVRIANLVEAHA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_COXB1
Sequence: MARYLGPKCRLSRREKTDLQLKSGIRAIDSKCNIERIPGMHWQRRGRTTDYGVQLRMKQMIKRYYDVLEKQFANYYKQADRLKGSTGDNLLKLLESRLDNVVYRMGFSATRAEARQLISHKAILVNGEVVNIPSYQVKPGDIIEVRSRAKGQLRIKGALELAQQRAPISWIEVDTKKMTGTFKEQPDVAELPAEFKVNLVVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: KHSE_BRUSI
Sequence: MAVYTDINEIELGAFLRHYDIGTLTSYKGIAEGVENSNYLLHTSSGSFILTLYEKRTNREDLPFFLGLMQHLAKRGLECPQPVVRNDGAMIGQLAGRPAAIVTFLEGMWMRRPTVAHCEAVGEGLAHMHLAGADFPMRRRNGLTLPDWRPLWNLSRKCADTVERGLVAETEADLDFLEKNWPADLPQGVIHADLFPDNAFFLGDRLSGFIDFYFACTDILAYDVAVCLNAWCFEKDFSYNRTKGAALLRGYTSVRPLSEAEADALPVLARGAAVRFMLTRLYDWLTVPAGSFVVKKDPMEYVRRMRFHRQIESAAEYGLEMQGVAA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: TGAL5_ORYSJ
Sequence: MIQSDAYTESAGYLAARPPTLEIFPSWPMSHLQEPYSNSQSVGSTTDSSSAQNTMSQAELVSPASMRSDSGQEQQQQEVLMVTIDDYNYKQGLGAAIATAPSFQQHAGGLDMRKHGSTRKDGKLLDAKTERRLAQNREAARKSRLRKKAYVQQLETSRIRLQQIEQELQRARSQGLFPGGCSAPGDMSSGAVMFDMDYTRWIDDDSKCMAELQGALQAQLPDGNLGAIVEECMRHYDELFHLRAVLASSDVFHLMTGMWAAPAERCFLWMAGFRPSEILKMLIPQLDPLTEQQLMGMCSLQQSSEQTEEALAQGLHQLHQSLADAVGGGPLNDGADVANYTGLMALALGRLENLESFYRQADNLRQETLHHMRRILTTRQTARCFLSIGEYNRRLRALSSLWASRPRENFIATENVSPTGTEFQVIQQSQQNQFSGF
What is the function of this protein?
Transcriptional regulator involved in defense response.
What are the official names of this protein?
Transcription factor TGAL5, bZIP transcription factor 41, OsbZIP41.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM1_CHLPN
Sequence: MVLGVVGISYREAALKERERAIQYLQSFEKNLFLAQRFLGKGGAFIPLLTCHRAELYYYSESPEIAQAALLSELTSQGIRPYRHRGLSCFTHLFQVTSGIDSLIFGETEIQGQVKRAYLKGSKERELPFDLHFLFQKALKEGKEYRSRIGFPDHQVTIESVVQEILLSYDKSIYTNFLFVGYSDINRKVAAYLYQHGYHRITFCSRQQVTAPYRTLSRETLSFRQPYDVIFFGSSESASQFSDLSCESLASIPKRIVFDFNVPRTFLWKETPTGFVYLDIDFISECVQKRLQCTKEGVNKAKLLLTCAAKKQWEIYEKKSSHITQRQISSPRIPSVLSY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: C295L_MOUSE
Sequence: MQRDTERAAQLSPSSEDEALVLRQKPLEMPAQEEDSTTLQQWKARQLQRLAEELKAEWQEARLQQVRQAERLYLSHLLDEAAERSMGNDPSVHEQNQRRTAKHTRAKERNRAAFREERGRREEHPRQHPKSRKKAPCSERRSSAKARGPASGEKGKRRRVSSSKDHDGYQGPRVTRRVGVAKLNPFFDGDTDCMEDVQKEFFREGRRPSAKGTHNLRDQSLQGKTTALTQPLLHGPTCKQEAAAQEPPSKYNKNLWHKEIESTFEELFNMNRKLKKHLNLHLEQRLKADQNPDEQQSYSEIRSETFGTPREERTEEVETAEESGSPTEVETTEMWSKVNLKQILSDSEYPRYQQIAKYPLKSESLVPVKAGTSREQDDLLSLSPESGQEPPKSPLLEDESLKPYLQKQADSVASWMALRQKQKAELEQRRQKALLELTEHPNMSLEIHYKAELEEERRARRRMRLALLKSNSTGICALPPDRNNLSLDNGLLDEDKQNQMIRDLQQQILEQNKLHQEFLEKARKRLQEFQKSF
What are the official names of this protein?
CEP295 N-terminal-like protein, Differential display clone 8, KIAA1731 N-terminal like protein.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Colocalizes to the motile cilium of mature spermatozoa.
Protein: PCX4_HUMAN
Sequence: MSPDVPLLNDYKQDFFLKRFPQTVLGGPRFKLGYCAPPYIYVNQIILFLMPWVWGGVGTLLYQLGILKDYYTAALSGGLMLFTAFVIQFTSLYAKNKSTTVERILTTDILAEEDEHEFTSCTGAETVKFLIPGKKYVANTVFHSILAGLACGLGTWYLLPNRITLLYGSTGGTALLFFFGWMTLCIAEYSLIVNTATETATFQTQDTYEIIPLMRPLYIFFFVSVDLAHRFVVNMPALEHMNQILHILFVFLPFLWALGTLPPPDALLLWAMEQVLEFGLGGSSMSTHLRLLVMFIMSAGTAIASYFIPSTVGVVLFMTGFGFLLSLNLSDMGHKIGTKSKDLPSGPEKHFSWKECLFYIIILVLALLETSLLHHFAGFSQISKSNSQAIVGYGLMILLIILWILREIQSVYIIGIFRNPFYPKDVQTVTVFFEKQTRLMKIGIVRRILLTLVSPFAMIAFLSLDSSLQGLHSVSVCIGFTRAFRMVWQNTENALLETVIVSTVHLISSTDIWWNRSLDTGLRLLLVGIIRDRLIQFISKLQFAVTVLLTSWTEKKQRRKTTATLCILNIVFSPFVLVIIVFSTLLSSPLLPLFTLPVFLVGFPRPIQSWPGAAGTTACVCADTVYYYQMVPRLTAVLQTAMAAGSLGLLLPGSHYLGRFQDRLMWIMILECGYTYCSINIKGLELQETSCHTAEARRVDEVFEDAFEQEYTRVCSLNEHFGNVLTPCTVLPVKLYSDARNVLSGIIDSHENLKEFKGDLIKVLVWILVQYCSKRPGMKENVHNTENKGKAPLMLPALNTLPPPKSPEDIDSLNSETFNDWSDDNIFDDEPTIKKVIEEKHQLKDLPGTNLFIPGSVESQRVGDHSTGTVPENDLYKAVLLGYPAVDKGKQEDMPYIPLMEFSCSHSHLVCLPAEWRTSCMPSSKMKEMSSLFPEDWYQFVLRQLECYHSEEKASNVLEEIAKDKVLKDFYVHTVMTCYFSLFGIDNMAPSPGHILRVYGGVLPWSVALDWLTEKPELFQLALKAFRYTLKLMIDKASLGPIEDFRELIKYLEEYERDWYIGLVSDEKWKEAILQEKPYLFSLGYDSNMGIYTGRVLSLQELLIQVGKLNPEAVRGQWANLSWELLYATNDDEERYSIQAHPLLLRNLTVQAAEPPLGYPIYSSKPLHIHLY
What are the official names of this protein?
Pecanex-like protein 4, Hepatitis C virus F protein-binding protein 2, HCV F protein-binding protein 2, Pecanex homolog protein 4.
What is the protein family that this protein belongs to?
Belongs to the pecanex family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLT13_HUMAN
Sequence: MRRFVYCKVVLATSLMWVLVDVFLLLYFSECNKCDDKKERSLLPALRAVISRNQEGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPDSQIPRRYYSLGEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTDDLCLDVSRLNGPVIMLKCHHMRGNQLWEYDAERLTLRHVNSNQCLDEPSEEDKMVPTMQDCSGSRSQQWLLRNMTLGT
What is the function of this protein?
Can glycosylate both unmodified peptides and glycopeptides that already contain an O-linked GalNAc sugar.  Transfers GalNAc to Thr-/Ser-rich tandem repeats GTTPSPVPTTSTTSAP of MUC5AC, specifically on Thr-3 of non-glycosylated MUC5AC peptide, on Thr-12 and Thr-13 of preglycosylated MUC5AC at Thr-3 (MUC5AC-3), on Thr-3 of preglycosylated MUC5AC at Thr-13 (MUC5AC-13) and on Thr-12 of preglycosylated MUC5AC at Thr-3 and Thr-13 (MUC5AC-3,13).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 13, Polypeptide GalNAc transferase 13, GalNAc-T13, pp-GaNTase 13, Protein-UDP acetylgalactosaminyltransferase 13, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: CCA_PSEA7
Sequence: MQIYKVGGAVRDRLLGRPVTDIDWVVVGASSEEMLARGYRPVGADFPVFLHPQSGEEYALARTERKSGRGYGGFTFHASPDVTLEEDLTRRDLTINAMAEDEQGRVIDPYGGQADLEARLLRHVSPAFAEDPLRVLRVARFAARYAGLGFRVAAETLALMRQLAGSGELQALTPERSWKEISRALMEPNPEVFVQVLHDCGALAELMPEVEALFGVPQPAAHHPEIDTGVHVLSVLQQCARHHQPLTVRWACLLHDLGKGLTREADWPRHIAHETRGLPLIDAINRRFRVPRDCQELARLVGEYHTHAHRALELRPTTLLELLQSFDVYRRPQRFEEFVAASEMDARGRHGLEQRDYPQAAYLLGAAQAARAVSVKPLVEKGLKGAELGEALKRARLAALKAYKEERGKA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: ASF1_DEBHA
Sequence: MSIVSLLGIEVLNNPAKFTDPYEFEITFECLEPLKEDLEWKLTYVGSSRSLDHDQELDSILVGPVPVGINKFLFQADPPSPELIPASELVSVTVILLSCSYADREFVRVGYYVNNEYDSEELRENPPAKVQVEHVVRNILAEKPRVTRFNIVWDNEDGNADEYPPEQQVDEEEEEEEEEEEEEDDEEEEEEKDVEGEEGEEGEDAEEAAEVEENGSKEASKEEDIEEDIEEDIEEDIEEDIEIEDEEEAKNADQGETPIDKVQS
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
What are the official names of this protein?
Histone chaperone ASF1, Anti-silencing function protein 1.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1742_SYNP2
Sequence: MIRIYTQQTQGQAWLSNHQQKSVVFACGLGFTDTALIPNISAAGATPEARKYTAIADAECICHGFREKAIYPLPPLIVGASPAILSRAILSHYQIPAYLFDTGLWLKPDKNAVDCIDVSGQKARCVSTGKALEFSTVNKLFEQGLTWGETLATQYLNHLFVLGECVVAGTTTALGVLTGLGYDANQKVNSSYIECNHDLKWQIVQTGLKKANLNPNPDPFAVVAAVGDPMQIFVAGMAIALSRTQGVLLAGGTQMLAVYALMERICKYHSLDFDPKNIAVGTTRWVAEDPTGDTVGLAELIGEVPLLATQLSFQTSQYSQLQSYEQGYVKEGVGAGGLAIAAHLAYGATQAELLAMIERTIVPYLAAN
What are the official names of this protein?
UPF0284 protein SYNPCC7002_A1742.
What is the protein family that this protein belongs to?
Belongs to the UPF0284 family.
Protein: AOFB_MOUSE
Sequence: MSNKSDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDNNNLWRTMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTKSTKQIATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQTGENVIVKTLNHEIYEAKYVISAIPPALGMKIHYSPPLPMLRNQLISRVPLGSVIKCMVYYKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGTYAAIMGFILAHKARKLVRLTKEERLRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVGKIFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESLDVPARPITSTFLERHLPSVPGLLKLFGLTTILSATALGFLAHKRGLFVHF
What is the function of this protein?
Catalyzes the oxidative deamination of primary and some secondary amines such as neurotransmitters, and exogenous amines including the tertiary amine, neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), with concomitant reduction of oxygen to hydrogen peroxide and participates in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:4156831).  Preferentially degrades benzylamine and phenylethylamine (By similarity).
What are the official names of this protein?
Amine oxidase [flavin-containing] B, Monoamine oxidase type B, MAO-B.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Protein: RL14_PROMA
Sequence: MIQQETYLTVADNSGAKRLQCIRVLGSNRRYAHVGDVIVAAVKDAVPNMGVKKSDVVKAVVVRTKATLRRETGNSIRFDDNAAVLINEDKNPRGTRVFGPVARELRERNYTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y886_HAEIN
Sequence: MNNLEKYRPYFLAFLRIVVAYMFILHGTAKFLEFPISMTGGNGAVGDPMLLVAGVIEIVGSILLILGLFTRQAAFILSVEMAYAYFFLHVAGKGNLFFPIANGGELALLYSLLFLYFVFSGAGACALDNKFFKK
What are the official names of this protein?
Uncharacterized protein HI_0886.
What is the protein family that this protein belongs to?
Belongs to the DoxX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCPP_VIBVY
Sequence: MSKKIMATQKVIIASLNPAKITAVESAFTSAFPDGTFEFVGVNVPSEVADQPMSDSETHLGALNRVRNAKACRADGAFYVGLEAGIDGNVTFAWMVIESHTHRGESRSASLMLPPNVIAKLPNANELGDVMDEVFGTENIKQKGGAISLLTQNQLTRSSVYHQALILALIPFTNPEHFPANLS
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: ACYP_LATSS
Sequence: MQKAVQLDVFGRVQGVGFRWTTKLVADRLGITGTVSNQPDGSVKIIAMGPDAILEQFIGAVKASPTPSGRVDRVVQTPLQDVSACHKFSVVG
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RS15_DECAR
Sequence: MALTTENKAAIVADYAQSKGDTGSPEVQVALLTARINDLTPHFKEHSKDHHSRRGLLHLVSQRRKLLDYLKGKNVERYRTLITRLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.