PharMolix/UniProtQA huggingface dataset:
Protein: RPOA_ACIBY
Sequence: MTRTANEFLTPQAIKVEAVSGTSAKVILEPLERGFGHTLGNALRRILLSSLPGAAVVEVEIEGVEHEYSTLEGLQQDIVELLLNLKGLSIKLFDQNEAYLTLEKQGPGDITAADLRLPHNVEVVNPEHLIGTLSATGSLKMRLKVSQGRGYETSDSRFPEGETRPVGRLQLDASYSPIKRVSYTVENARVEQRTDLDKLVIDLETNGTVDPEEAIRKAATILQQQIAIFVDLQKDQTPVAQEPREEVDPILLRPVDDLELTVRSANCLKAENIYYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASKGLQLGMRLENWPPASLRMDDRFAYRSR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PHLN_PSEAE
Sequence: MISKSRRSFIRLAAGTVGATVATSMLPSSIQAALAIPAHRRHGNLKDVEHVVILMQENRSFDHYFGTLKGVRGFGDRMAIPLPDGQRVWHQKGSKGEILPYHFDTSTTSAQRVDGTPHTWPDAQQAWNEGRMDKWLPAKTERSLGYYKEQDIAFQFAMANAFTICDAYHCSFQGGTNPNRLFLWTGTNDPLGQHGGPVTTNDHDSNGPVEQGYTWTTYPERLQAAGITWRVYQDMADNFSDNPLIGFRQYRAAAPDSPLIVNGLSTWKLDALKRDVLANSLPQVSWIVAPAKYSEHPGPSSPIWGAEYTSWVLDALTANPEVWSKTALLVMFDENDGFFDHVAPPAAPSLNKDGTLRGKTTADATLEWHTKGDIRYRNQPYGLGPRVPMYVISPWSKGGWVNSQVFDHTSVIRFLEQRFGVMEPNISPWRRAVCGDLTSAFNFANPNNEPFPELPDTSQADAIVASQIKLPKPKPPAVAAMPKQEMGIRPARALPYELGVHARYRSGGDALSLTFANTGKAGAVFQVFDLLDSENPPKRYTVGARKRLHDSFQGDASGDYHLEVHGPNGFLRVFRGNLRRDLAERKAPLPEVRIDYEPLFGNLRVQLINRGRHPVKLTVKDNVYRQGERRTVNVPPGQRREVRYSLRSSGNWYDFSVSAQGADSFLRRFSGRMEDGRSGFSDPGMGLGTLTF
What is the function of this protein?
Hydrolyzes phosphatidylserine as well as phosphatidylcholine.
What are the official names of this protein?
Non-hemolytic phospholipase C, PLC-N, Phosphatidylcholine cholinephosphohydrolase, Phosphatidylcholine-hydrolyzing phospholipase C, PC-PLC.
What is the protein family that this protein belongs to?
Belongs to the bacterial phospholipase C family.
Protein: Y1330_METJA
Sequence: MDAGMDLYIGSNEERDRVKEKLKEILLKQLSNPNVSTLLIAAILLDNEGRANNLPFNYNEDPNYVYVDEVIGLAIANEIAGTKAIFNFRFYDAKKPGIIGELDRKGFMFLDDAIAGLLAGCMSKVFE
What are the official names of this protein?
Uncharacterized protein MJ1330.
Protein: COP2_STAAU
Sequence: MTFNKIFKYLISLLFLSILFHTIIHKNNLVFSKTMHKKVAFFSFSFFFVWIRHLKRYNSMLEKATFFVLQTSYTNELKGLYIAGNSYPYYQDKKKLVFNSFQKPFKNHQSTKIPRE
What is the function of this protein?
Putative control of replication message.
What are the official names of this protein?
Protein cop.
Protein: CPFC_LACLM
Sequence: MDKKKGILLVALGTPRSCETEDVREYLKEFLGDPLVIQKPRWLWLPILNGIILKVRPQKSAEMYKQIWTDEGSPLMSYTIAQTEQLQGLREDFDVRFAMTYGEPRIDKVIREMKESGVEDITVLPLYPQYSLTTVEPIIQQVKKIDDKINVIRDFHQIESYTDLLAESIREKWQANHYDKLILSYHGIPLSYVTKKKDAYEAQCIETTRLFVEKLGLKEEEYEHTYQSKFGPEKWLEPATIDRIAELPKEDTKKVLICSPAFVADCLETLFELEIENKEVFVENGGETFDFVHPFNDSLEFTKVLSEVIEKNKVEVEV
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAB_TETOB
Sequence: MATKLFPKFSQGLAQDPTTRRIWFGLAVAHDFESHDGMTEENLYQKIFASHFGQLAIIFLWTSGNLFHVAWQGNFEQWGADPIHVRPIAHAIWDPHFGQPAVEAFTRGGASGPVNISTSGLYQWWYTIGMRTNQDLYVGSVFLALVSAIFLFAGWLHLQPSFQPSLSWFKDAESRLNHHLSGLFGVSSLAWTGHLVHVAIPESRGKHVGWDNFLTQLPHPQGLTPFWTGNWAAYAQNPDSASHIFGTSDGAGEAILTFLGGFHPQTQSLWLTDMAHHHLAIAVLFIVAGHMYRTNFGIGHRMSAILDAHVAPSGRLGAGHKGLFETVNNSLHFQLGLALASVGTICSLVAQHMYSLPPYAFLANDFTTQAALYTHHQYIAGFIMCGAFAHGAIFWIRDYDPEQNKGNVLSRMLDHKEAIISHLSWVSLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPVFAQWIQAAHGKAFYGFDLLLSSSSSSASSASQTLWLPGWLDAINNNQNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAYDAFYLAVFWMLNTIGWVTFYWHWKHLTLWQGNVSQFDESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLAGHLVYATGFMFLISWRGYWQELIETLVWAHEKTPLANLVYWKDKPVALSIVQARLVGLAHFSVGYVFTYAAFVIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: SNX3_RAT
Sequence: MAETVADTRRLITKPQNLNDAYGPPSNFLEIDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVPPLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHPLAQNERCLHMFLQDEIIDKSYTPSKIRHA
What is the function of this protein?
Phosphoinositide-binding protein required for multivesicular body formation.  Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)).  Can also bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2).  Plays a role in protein transport between cellular compartments.  Together with RAB7A facilitates endosome membrane association of the retromer cargo-selective subcomplex (CSC).  May act in part as component of the SNX3-retromer complex which mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway.  Promotes stability and cell surface expression of epithelial sodium channel (ENAC) subunits SCNN1A and SCNN1G.  Not involved in EGFR degradation.  Involved in the regulation of phagocytosis in dendritic cells possibly by regulating EEA1 recruitment to the nascent phagosomes.  Involved in iron homeostasis through regulation of endocytic recycling of the transferrin receptor Tfrc presuambly by delivering the transferrin:transferrin receptor complex to recycling endosomes; the function may involve the CSC retromer subcomplex.  Involved in regulation of neurite outgrowth in primary neurons.
What are the official names of this protein?
Sorting nexin-3.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
Protein: RECA_LEVBA
Sequence: MADERQAALDKALKKIEKDFGKGSIMRLGDNSNLEVETVPSGSLALDVALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKRGGTAAYIDAENALDPAYATALGVNIDDLLLSQPDTGEQGLQIADALISSGAIDIVVVDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGTINKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATVRLEVRRAEQIKDGTDVIGNRTRIKVVKNKVAPPFKRAEVDIMYGQGISQTGELLDMAVEKDIVDKSGSWYSYGEDRIGQGRENAKQYLADHPDMMAEVNQRVRAAYGVGDEEAAATKATETKTDAPKDKDKGKTKAKDKPADVTPGQIELAPDKSAK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_KLEP7
Sequence: MRVTDFAFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDILDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESIKATMLARHGALFEVEFNDERPVLEILNGIGHMPLPPYIDRPDEDADRELYQTVYGTRPGAVAAPTAGLHFDEPLLDKLRAKGVEMAFVTLHVGAGTFQPVRVDSIEEHTMHSEYAEVPQEVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKDALIAPFFDDTQIFIYPGYQYQVIDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKVAVEQKYRFFSYGDAMFITYNPQAISERP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MALT_VIBPA
Sequence: MWIPSKLTRPGRLHNAIVRPRVLDLLQQAPYYKLVLFRSPAGYGKTTMAAQWLSDKPNVGWYSIDDSDNDGFRFVNYLLQALNKATNFSCSNAQKLAEKRQISSLRSLFSEVFAEMADFHQECYVVLDDYHLITNDEIHESMRFFLKHMPDNLTVVVTSRAAPPLGTANLRVRDLMIEIGNEMLAFDTEETTRFFNQRIADGIDEDMANSLRTYVEGWPSAMQLIALQAQHQNRTLAQTVESVSQFNHAHLWDYLVEEVFDLLDHETRHFLMQVSVLDHFNDELVFALTQREDALGLIESLNRYGLFIYPLEGEHNWFRFHNLFGEFLSHERQARIPQQEKDLHRNAAVAWLQQKSPHQAIHHAQKSNDKDLVVEILNEFGWKMFNQGELSTLEHAINKLDAELLFSHPKLTMLRAWLAQSQHRYNQVGQLLEEAEEEHKKRNIELDIHYQGQANALLAQVAINSNQPEKALELAELALSQLDNTIYRSRIVATSVVGEVNHVLGKLDRALPMMQQTEKLARQYQVYHQALWAILQQSEILIAQGYVQAAFELQDSGFRLIEDQQLQHVPLHEFLLRIRAQVLWCWNRLDEAEECAYRGLQILENHSPSKHLHSYSMLARIAIGRGELDKAGKFIEHIQHLMKQSTYHVDWTANASLSLILFWQARGNTEAMQEWLNTAVRPESACNHFLQLQWRNIVRAHINLGQYEEARQALNFLQSEARRTNLITDTNRNLVVEAVLAARQKDEEQAKALLKEALVMTNQTGMVGNFLIDGATIGGLLEKLSLRHELGDLERHRAQQLMKDISSNQRSRSIHFDEDFIEKLVNHPNVPELVRTSPLTQREWQVLGLIYSGFSNEQIAQELDVAGTTIKTHIRNLYQKLNIANRKEAIVTAENLLQLMGY
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: CCR4_EMENI
Sequence: MYSQTHQQQHVIMNGGQAHQRFGMQMKFQTQNHHPHPAQQPHHHAHHNQPPQHVGHQHNFSSGALASATPHFTPSHIQNGTHTNIDEELDESMNEHWQQQLQLAAESRQASSPHYYARAVAQQTKGIQIAPSQPEAQENGVNQKNGITKTKPASRQGWHALDFGGQGLRALAPSLFKYAFLEKLYLSHNKLKVLPPQIGQLRKLTHLDLSANDLTELPEEIGMLTNLRHLLLFDNNIRTLPYEMGYLYRLEILGIEGNPLEDVLKSLIMKEGTKALIRYLKEEMPVHVPPPARDWLVLDETAATSPDKVSVLSYNTLCDSSATQSHYGYAPSRVLSWEFRRETILNELRAHDPDIICLQEIDQGSYNEFFREQLAYSDYKGVFWPRGRAMGMQEEDAKGVDGCATFFKGSKFILLDKQVINFGQTAVRRPDAKGQDDIYNRLWQKDHIAVIVFLENRQTGSRFIIVNAHLYWDPAFKDVKLIQTAILMEEITKHSEKYAKWPPCTDKAAFRFREAQGEQTMPEPAPSAEYASGDQIPLFMCGDFNSSPGSAAYNLIANGGLIEEHPDLEKRMYGNLSKVGMTHPFKLKSAYGAIGELSFTNYTPDFKDILDYIWYSSNTVHVSGLLGEVDKDYLQRVPGFPNYHFPSDHIALLAEFSVKGKKGKVVEADFGPQRN
What is the function of this protein?
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity).  Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
What are the official names of this protein?
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4, Carbon catabolite repressor protein 4, Cytoplasmic deadenylase, Glucose-repressible alcohol dehydrogenase transcriptional effector.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VE1_HPV40
Sequence: MADSPGTEDGGAGCSGWFVVEAVVDKQTGDAVSEDEDEEDIEDSGFDMIDFIDNSVVAEEHVELSNAQALLHVQQTCADAADLCELKRKYISPYVSPIQYSEPSIDGDLSPRLHAIRLGGGQKAKRRLFQRVEQRDSGYGYSEVETTERQVETEHGGPEDTVGGSGRVTTDEAEAVEVVEDGSHVIDHCSPRTQLIELFKCKDLNAKLYGKFKELYGVGFGDLVRQFKSDKSTCTDWVYAVFGVNPTIAEGFHTLLKRQALYLHTQWTSCKWGMVLLALCRYKVGKNRETVVRQLSKMLNVPDNQILVQPPKLQSPPAALFWFRAGMGNGSEVSGTTPEWIAKQTMLEHSFADTQFSLTDMVQWAYDNGHTDECEIAYYYAQRADVDANAAAFLKSNNQAKYVRDCASMCKHYRLAEMRRMSMAEWIKHRGEKCDEGDWKPIVKLLRYQHIDIIVFLAALKKWLQGIPKKNCICIVGPPDTGKSCFGMSLMHFMQGTIISYVNSCSHFWLQSLADAKVAMLDDVTAACWGYMDTHMRNLLDGNPTSIDRKHKPLAVIKCPPLLLTSNINITQDSKYQYLQSRVQVFEFPNPFPFDSNGNAVYELNDANWNSFFKRLASSLELQTPGDEDGESSQAPRFVPGTVVRTV
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: TIG_THEP1
Sequence: MEVKELERDKNRVVLEYVFGAEEIAQAEDKAVRYLNQRVEIPGFRKGRIPKNVLKMKLGEEFQEYTLDFLMDLIPDTLKDRKLILSPIVTERELKDVTARVVVEVHEEPEVRIGDISKIEVEKVDEEKVLEKYVERRIEDLRESHALLEPKEGPAEAGDLVRVNMEVYNEEEKKLTSREYEYVISEDEDRPFVKDLVGKKKGDVVEIEREYEGKKYTYKLEVEEVYKRTLPEIGDELAKSVNNEFETLEQLKESLKKEGKEIYDVEMKESMREQLLEKLPEIVEIEISDRTLEILVNEAINRLKREGRYEQIVSSYESEEKFREELKERILDDIKRDRVIEVLAQEKGISVNDEELEKEAEELAPFWGISPDRAKSLVKARQDLREELRWAILKRKVLDLLLQEVKVKVVEPKGEGDDSEGKEDN
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RS3_MYCMS
Sequence: MGQKVSPNVLRLGIVRDWENRWYAEKDQYVKWLDQDIKIRTALFKLLKDAAVSKIDIERTTKDLTLFIKTARPAIVLGQEGKNIEKIVLAVRKTVKNKKLIVNVRVIEIKSPDADATLVARWIGEQISNRASFRTVQKLAIKKALKAGAKGIKTAVSGRLGGVEMARTEGYLEGSVPLSTLRNNIDYALYEAPTTYGQIGVKVWINHGEVFKKERMNNSQIMAKPRTNKGGKR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GSTA5_RAT
Sequence: MPGKPVLHYFDGRGRMEPIRWLLAAAGVEFEENFLKTRDDLARLRSDGSLMFEQVPMVEIDGMKLVQTKAILNYIATKYNLYGKDMKERALIDMYAEGVADLELMVLYYPYMPPGEKEASLAKIKDKARNRYFPAYEKVLKSHGQDYLVGNKLSRADVSLVELLYHVEEMDPGIVDNFPLLKALRTRVSNLPTVKKFLQPGSQRKPFDDEKCVESAKKIFS
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Has substantial activity toward aflatoxin B1-8,9-epoxide.
What are the official names of this protein?
Glutathione S-transferase alpha-5, GST A5-5, Glutathione S-transferase Yc-2, GST Yc2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYND_CELFI
Sequence: MSDSFEATRTTRRRRPLQALTGLLAAGALVAGALAAASPAAAAVTSNTTGTHDGYFYSFWTDSPGSVSMDLNSGGGYTRWSNTGNFVAGKGWSTGGRKTVSYSGQFNPSRNAYLTLYGWTQSPLVEYYIVDSWGTYRPTGTFMGTVTSDGGTYDIYRTQRVNKPSIEGDSSTFYQYWSVRQQKRTGGTITSGNHFDAWASKGMNLGRHNYMIMATEGYQSSGSSSITVSEGSGGGGGGDTGGGGGSTGCSVTATRAEEWSDRFNVTYSVSGSSAWTVNLALNGSQTIQASWNANVTGSGSTRTVTPNGSGNTFGVTVMKNGSSTTPAATCAGSGGGTATPTPTPTPTPTPQSCSAGYVGLTFDDGPNTGTTNQILSTLTQYGATATVFPTGQNAQGNPSLMQAYKNAGVQIGNHSWDHPHLVNMSQSDMQSQLTRTQQAIQQTAGVTPTLFRPPYGESNATLRQVESSLGLREIIWDVDSQDWNNASASQIRQAASRLTNGQIILMHDWPAATVQALPGILQDLRSRNLCTGHISSSTGRAVAPSSAGGGGGGGGGTGSCSVSAVRGEEWADRFNVTYSVSGSSSWVVTLGLNGGQSVQSSWNAALTGSSGTVTARPNGSGNSFGVTFYKNGSSATPGATCATG
What is the function of this protein?
Endo-acting xylanase which displays no detectable activity against polysaccharides other than xylan.  Hydrolyzes glucosidic bonds with retention of anomeric configuration.
What are the official names of this protein?
Bifunctional xylanase/deacetylase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
Protein: KAD_PSELT
Sequence: MKIVLLGAPGAGKGTLAKDLSIMFSVPHISTGDMFREAVAAGTELGVKVQNILSSGALVPDEIVNQVVEERLRKQDCEKGFIFDGYPRTIAQAIALDEILQKMSKKLDLAIYLEASEETVVKRLTSRRICPKCGKIYNLISMPPVSDQICDDCGEQLVIREDDKEEVVRKRYRLYLETTAPLVEYYSGRDILVSVNSERDHRKLVEDVSRLLKKVIS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTOX_ESCF3
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMIDAHMPPHQQGSHHGDTRLIRHAYGEGEKYVPLVLRAQQLWDELSTHNEEPVFVRSGVINLGPENSEFLANVAHSAEQWQLPVERLDATAITSRWPEIRVPENYIGLFESESGFLRSELAIETWIRLAKEAGCAQLFNCPVSAIRHEGDGVTVVTEDGEYSARKVLISAGTWVKSLLPELPVQPVRKVFAWYQADGRYSIKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQSISNAAERLPFAEVASDGSEAFPFLRSVLPGIGCCLYGASCTYDNSPDEDFIIDTLPGHDNTLVITGLSGHGFKFASVLGEIAADFAQGKPAAFDLTPFKLSRFK
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: MNMA_BORHD
Sequence: MKIAVLLSGGVDSSVALYTMIQKGYKNIKCYYLKIWLEDELSYIGECPWEEDINYVEAVCTKFNVPYEIISLQDEYYKRVVTYAIEELKIGNTPSPDIFCNQRIKFGAFFDKINEHYDLIVTGHYAKIENKNNHYILKQAKDKIKDQSYFLSHLSREQISKLHFPLGDLLKTEIRQIAHKIDLPNKNRKDSQGICFLGKIKYDEFIKYHLGELKGNIIEQETGKILGTHNGYWFFTIGQRKGIKLSHGPWFVTEKDIQNNIIYISNSVNYLAQGKHQFLVHKTNWINKPVNNIDLSAKIRHGEKKIKCKIEMLKNDIIKVDLEEKDYGISPGQFCIFYQEDECLGGAQILQTLT
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_PSEPF
Sequence: MLIVADENIPLLDAFFAGFGEIRRVPGRSIDRATVEQADVLLVRSVTNVNRALLEGSKVRFVGTCTIGTDHLDLDYFNEAGITWSSAPGCNARGVVDYVLGSLMTLAEIEGVDLRERTYGVIGAGEVGGRLIKVLKGLGWNVKVCDPPRQAAEGGDYVSLEQIIAQCDVISLHTPLTRSGDGATWHLFDEQRLQQLKPGAWLINAARGPVVDNTALREVLLEREDLQAVLDVWEAEPQVDVSLAELCVLATPHIAGYSLDGKQRGTAQIYQAYCDFIGEPASIQLGDLLPAPWLSEVSLHADSDPAWALAMLCRGVYDPRRDDADFRRTLLGSVGEQRAAFDVLRKQYPSRREIEGLKVRIEGDSPALRQIVAALGAVAV
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCPP_HALH5
Sequence: MWTIMIGSKNRAKVHALQEVVIRDKIIVRSEAVPSDVASQPFSDQETIQGAINRANHCLSFDGVDYGVGLEGGVVRSEYGLFLCNWGALVSQTGDQWVAGGARVPLPQEVAHELEGGKELGDIMESLTKNPDVRMTDGAIGYLTDGEISRKAMFQHVVHLLIGQARRDGHLLRTVTH
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Probable inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: Y489_HAEIN
Sequence: MDIFSFFSADFWQANSLCFMFISAFLSATVLPGNSEVIFVALAVPKLMLGSLFNVDILALILIATAGNSLGSLTTYGIGRWMPKFDPKNYRTLWAINQLRRYGAIALLLSWLPVVGDLFCAIAGWLRLNFVTSSLFIFLGKMVRYVALLFLSTPFLL
What are the official names of this protein?
Uncharacterized protein HI_0489.
What is the protein family that this protein belongs to?
To E.coli YqaA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TCP17_TRYCR
Sequence: MSVVASGRVAANLQRLGIKLPAAAAPATNYVSYVCSGMQLHVSGQLPKNDVGGCMTGQLGASLTVTEGQAAARACALQVVSQMQAALGDLDRVKRVVKLNVFVNSSPSFTEQSYVANGASDLILSVFGEEVGRHARCAVGVAQLPFGAAVEVDALVELNN
What are the official names of this protein?
Protein TCP17.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_ACIAD
Sequence: MTDPSQVKPKHVMMMAAGTGGHVFPALAVAKQLQQHGCQVSWLATPAGMENRLLKDQNIPIYQIDIQGVRGNGAVRKLLAPFKILKATYSAMRYMKQLKVDAVAGFGGYVAGPGGLAARILGIPILIHEQNAVAGFTNTQLARVASKVCEAFPNTFPASAKRVTTGNPVRKEITAILSPKWRYDSREQAGQPLNILIVGGSLGAQALNERLPDALKNLNLPLNVFHQCGQKQFEETRVRYTNAPANMSVQVMPFIEDMAQAYRDADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQTANARFLADVGAAKICQQSTMTPENLDALLKPLMNRQLLSEMAVKARQHAQPNATQHVVDLIQTL
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL21_BURP6
Sequence: MYAVIKTGGKQYKVAVGEKLKVEQIPADIDAEITLDQVLAVGEGESIQFGTPLVSGASVKATVVSHGRHAKVTIFKMRRRKHYQKHGGHRQNYTELRIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PANB_XANC5
Sequence: MSSHADSKPWTVPALAQAKREGRKLVMLTAYDAGFARTFDAHGVDLILVGDSLGMVVQGHDSTLPVTTADMVYHTAAVARALDRALLVADLSFQADATPERALDAATQLLQAGAEMVKIEGAGHKLEVIRYLVEREIPVCSHLGLTPQSVLRFGGYKVQGRGEAGEQLRRDAQAVVDAGASLLVLECVPTPIATQISADLSVPTIGIGAGPGCDGQVLVMHDMLGLDSGHRRPKFVKDFLAEGGSVAGAVRAYAQAVRDGSFPDAEHAYAA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMA21_DROYA
Sequence: MSTKNKKAAGGNGGAPKQTRQQSHDSQDYSSFKTVLFYCMLIVFLPVLTFFVLKGFVLDQFLDISEVKVNIASAVGAVVALHVALGLYIYRAYFGAPGSKASKTD
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein VMA21 homolog.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.