PharMolix/UniProtQA huggingface dataset:
Protein: PBP2A_STRP2
Sequence: MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGPIRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKEAGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGSTITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVEDASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYIDKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYRIYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDKTGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGIKTSREVPMYQSLAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGVETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTSMMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFPTTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQTNDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan (PG) from the lipid intermediates (By similarity).  Binds dansylated lipid II and catalyzes the polymerization of glycan chains.  Hydrolyzes S2d (N-benzoyl-D-alanylmercaptoacetic acid) molecule, a synthetic thiolester analog of cell wall stem peptide.  Active against bocillin, a fluorescent penicillin.  No transpeptidase activity with non-fluorescent lysine-containing lipid II as substrate (By similarity).
What are the official names of this protein?
Penicillin-binding protein 2a, PBP2a, Cell wall synthase PBP2a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Secreted, cell wall. Note=Localizes to sites of new peptidoglycan (PG) synthesis at midcell independently of MacP.
Protein: IFIT3_HUMAN
Sequence: MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYLQGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN
What is the function of this protein?
IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication.  Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription.  Exhibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27.  Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation.  IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels.  Up-regulates CDKN1A/p21 by down-regulating MYC, a repressor of CDKN1A/p21.  Can negatively regulate the apoptotic effects of IFIT2.
What are the official names of this protein?
Interferon-induced protein with tetratricopeptide repeats 3, IFIT-3, CIG49, ISG-60, Interferon-induced 60 kDa protein, IFI-60K, Interferon-induced protein with tetratricopeptide repeats 4, IFIT-4, Retinoic acid-induced gene G protein, P60, RIG-G.
What is the protein family that this protein belongs to?
Belongs to the IFIT family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: YLN8_SCHPO
Sequence: MRKLRCKQMIPKLLPFIFIYLSVANKIMFYCILNERAFKHYKTYRRITDCPEIKNKKSRRKNQRNSSSIGLSNPNKFSIYIYIYFFFYSFLCSPYLFKYISLF
What are the official names of this protein?
Uncharacterized membrane protein PB8E5.08.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: THIO_MYCSM
Sequence: MSEDSATVAVTDDSFSTDVLGSSKPVLVDFWATWCGPCKMVAPVLEEIAAEKGDQLTVAKIDVDVDANPATARDFQVVSIPTMILFKDGAPVKRIVGAKGKAALLRELSDAL
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: APBE2_KLEP3
Sequence: MSDNRVYSYSAVLMGSPILLKLYSHDEALASRVFQLIKRYEDLLTVNRAESQVMDINHAAGRHPVTVSRPVFQLIQCAKAASMVRDSAFNLAIGPLVKLWRIGFHGHSVPDAADIRARLALTRPQEVILDETTCSVFLQQPGMELDLGAIAKGYIADRVRDYLRQQQVEKALINLGGNVHTLGEWTIGLKKPFADAQALIGSLTINGQSVVTSGTYERYFEQDGKRWHHILDPRSGYPLDNELDSVTVISTDSLDGDIWTTLLFGLGVEKGCAALRQREDIDAIFVTKNRDIILSSPQRLRFSPLDSGYQVIDCTA
What is the function of this protein?
Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.  Is responsible for the modification of the fumarate reductase KPK_2907.
What are the official names of this protein?
FAD:protein FMN transferase, Flavin transferase.
What is the protein family that this protein belongs to?
Belongs to the ApbE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPB45_MYCTU
Sequence: MAGDQELELRFDVPLYTLAEASRYLVVPRATLATWADGYERRPANAPAVQGQPIITALPHPTGSHARLPFVGIAEAYVLNAFRRAGVPMQRIRPSLDWLIKNVGPHALASQDLCTDGAEVLWRFAERSGEGSPDDLVVRGLIVPRSGQYVFKEIVEHYLQQISFADDNLASMIRLPQYGDANVVLDPRRGYGQPVFDGSGVRVADVLGPLRAGATFQAVADDYGVTPDQLRDALDAIAA
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC45.
What are the official names of this protein?
Putative antitoxin VapB45.
Protein: TVA1_MOUSE
Sequence: MLLALLPVLGIHFVLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYSATPYLFWYVQYPRQGLQLLLKYYSGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDSAVYFCAVSGFASALTFGSGTKVIVL
What are the official names of this protein?
T-cell receptor alpha chain V region PHDS58.
Protein: Y329_PECAS
Sequence: MKRTKNINQETFRKEWRTHRLAPVALAVSAVFFLAGCEQTDETVSLYQNADDCSSANPSMAAQCTTAYNNALKEAEKTAPKYATKEDCVAEFGEAQCTQTPAPAQAGMAAEPQQSGGMSWMPLMAGYMMGRMMGGGAGFAQQPLFSPKTPASPANGQFVDAAGKNYGNAATGRTMTVPKTALAPKPATTSTITRGGFGETVAKQNSMQRSSASSNSSSSRSMGG
What are the official names of this protein?
UPF0441 protein ECA0329.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: ADEC_ECOLU
Sequence: MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYTDAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: KGUA_RHORT
Sequence: MSAPSSAPALIPRRGMMLVLSSPSGAGKTTISRALLAEEDGLEMSVSVTTRAPRPGERDGEHYHFIDVARYMALTKDDGLLEHARVFENYYGTPRAPVEAALARGCDVLFDIDWQGTQQVAEKARTDLVSIFILPPSVGELERRLKGRAQDSDAVVAARMAKAMDEISHYFEYDYIIVNDDLDRSIADVRAILRAERLKRARRIGLAEFVNRMRGAGE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD2_PSESM
Sequence: MLQAASALRHAKRILVITGAGLSADSGLPTYRGVGGLYNGETEDGLPIEMALSGPMLRRDPELCWKYIAELGKACLGGEPNVAHYAIAQLQRIKPECWVLTQNVDGYHRAAGSPPERLIEIHGQLSPLFCQSCAAQDPQLSEHLQRPLPPLCRLCGGILRPPVVLFQEMLPERALETLYEQLATGYDAVLSIGTTASFPYIHEPVIRTRVSGGFTAEINPQPTDHSAQMDVFLQCRAAHVMAELISHI
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacylase 2, Regulatory protein SIR2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_DESAH
Sequence: MDKAVLETQFPDMNLVRKGKVRDIYDTGEAFLMVTTDRLSAFDVVLPNGIPGKGKVLTKISEFWFKQMAPLVGNHLISTDVADFPDVCQPYAKVLSGRTMLVKKAEPLPVECIVRGYISGSGWKSYQNNGTLCGITLPKGLVESDRLPEPLYTPSTKAEVGDHDINIDFAKTVDLIGRERAEKLRDLSIQIYLKGAQTALKKGIIIADTKFEFGLVDDEVILIDEVMTPDSSRFWPMDTYAPGGAQKSYDKQFVRDWLVSSGWDMKAPGPEIPQDVIAGTVAKYQEVLELITGQK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: VSPBF_MACLB
Sequence: MVLIRVLANLLLLQLSHAQKSSELVVGGDECNINEHRSLVFLYNSSFGCGGTLINQEWVLSAAHCDMENMRIYLGWHNFSLPNMNQKRRVAKEKFFCLSSKNYTEWDKDIMLIKMNRPVTYSTHVAPLSLPSSPPSVGSVCRIMGWGAITSPNETYPDVPHCANINILNYTVCRAAHPWLPAQSRTLCAGILQGGIDTCKGDSGGPLICNGQIQGIVSWGDNPCAQPLKPGHYTNVFDYTDWIQSIIAGNTTATCPP
What is the function of this protein?
Snake venom serine protease that has fibrinogenolytic activities by hydrolyzing the beta chain of fibrinogen (FGB).  Typical arginine esterase which hydrolyzes esters and amides of arginine.
What are the official names of this protein?
Beta-fibrinogenase, VLBF, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DEGS1_DROME
Sequence: MGQKVSRTDFEWVYTEEPHASRRKIILEKYPQIKKLFGHDPNFKWVAGAMVLTQILALFVVKDLSWSWLIVAAYCFGGIINHSLMLAVHEISHNLAFGHSRPMHNRILGFICNLPIGLPMSISFKKYHLEHHRYQGDEAIDTDIPTLLEARLFDTTFGKFLWVCLQPFFYIFRPLIINPKPPTRLEIINTVVQLTFNALIVYFLGWKPLAYLLIGSILAMGLHPVAGHFISEHYMFAKGFETYSYYGPLNWITFNVGYHNEHHDFPAVPGSRLPEVKRIAKEFYDTMPQHTSWTRVLYDFIMDPAVGPYARVKRRQRGLAS
What is the function of this protein?
Has sphingolipid-delta-4-desaturase activity.  Converts sphinganine-containing sphingolipids (such as N-acylsphinganines or dihydroceramides) into sphingolipids containing the delta-4-desaturated sphingoid base (E)-sphing-4-enine (such as N-acylsphing-4-enines or ceramides), which are required for many different functions (structural functions as well as signaling) (PubMed:11937514).  Required to initiate spermatid differentiation among other signals (PubMed:9003299).  Required for central spindle assembly and cytokinesis during male meiosis, may act as part of an anchoring mechanism that links membrane-bounded cellular compartments to components of the cytoskeleton (PubMed:9819060).
What are the official names of this protein?
Sphingolipid delta(4)-desaturase DES1, Degenerative spermatocyte homolog 1, DES-1, Dihydroceramide desaturase-1.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Mitochondrion.
Protein: SELO_BACCR
Sequence: MTKNNETGWNLDNSYTTLPQSFYTEIPPTPVSSPELVKLNHSLAISLGLTPEELKKEAEIAIFAGNGLPEGAHPLAQAYAGHQFGHFNMLGDGRALLIGEQITPSGERFDIQLKGSGPTPYSRRGDGRAALGPMLREYIISEAMYALDIPTTRSLAVVTTGEPTYRETKLPGAILTRVASSHIRVGTFQYAAARGSIEDLKSLADYTIKRHYPEIESHENRYTALLQEVIKRQASLIAKWQLAGFIHGVMNTDNITISGETIDYGPCAFMDNYDQGTVFSSIDTQGRYAYGNQPYMAAWDLARLAESLIPILHEDEEEALKIAQDEISKFSVQYEKQWFLGMKKKLGLFSNEEQDHSLIEQLLKMMEKYKADYTNTFRSLTLDAIENTALFESPEFKEWYKLWQSRLDRQEQSKENAYEMMKNNNPSIIPRNHRVEEALEAAVTNDDYSVMEKLLEALSNPYAYSTDQEEYCAPPAPTNRPYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: PUR2_VIBPA
Sequence: MRVLIIGSGGREHALGWKAAQNPNVETIFIAPGNAGTALEPKLENVNIDVEDIAGLVAFAKEKAIELTIVGPEAPLVIGVVDAFREAGLPIFGPTQAAAQLEGSKAFTKDFLARHQIPTGAYANFTEIEPALAYVREQGAPIVVKADGLAAGKGVIVAMTLEEAEDAIKDMLAGNAFGDAGSRVVIEEFLDGEEASFIVMVDGENVLPMATSQDHKRVGDKDTGPNTGGMGAYSPAPVVTPEIHNRIMEEVIYPTVRGMASEGNPYTGFLYAGLMIDKDGTPKVIEYNCRFGDPETQPIMMRMESDLVDLCLAAIDEKLDQVESKWDPRASIGIVLAAGGYPAAYNKGDVISGLPQVEIEGEKVFHAGTDNQDGDIVTNGGRVLCATALGNSVSEAQQRAYELAKQISWDGMFHRNDIGYRAIAREQEK
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: AROC_PAEAT
Sequence: MLRWLTAGESHGPALIGIVEGVPAGVELTSGQIRDALARRRLGYGRGARMKFEQDEVTIMGGVRHGLTQGGPVAIQVGNTEWPKWEQIMSADPVDPEVLADQARNAPLTRPRPGHADFTGMQKYGFDEARPVLERASARETATRVALGTVAAQFLKQLGIELVSHTVSIASVTVPEGRPLPLPKDVIALDADPLRCFDRETSNAMVAEVDAAHKEGETLGGVVEVLAYGLPPGLGSYVHWDRRLDSRLAAALMGIQAIKGVEVGDGFLTAARRGSAAHDEILKDENGKIVRQTNRAGGIEGGMSIGEVLRVRAAMKPIATVPRALRTIDVSTGEPAKAHHQRSDVCAVPAAGVVAEAMVALVLAEAVAEKFGGDSVPETQRNLQSYLESIPATLDSVGR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RIMP_ECO45
Sequence: MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_PARXL
Sequence: MSFSPSIAGLSGPLSALSDALTTAPESAFASLGSVFLTRLPAAPLSAPYVVGFSAETAALLGLEPGIENDPAFAELFSGNATREWPAEALPYASVYSGHQFGVWAGQLGDGRALGLGEVEHGGRRFELQLKGAGRTPYSRMGDGRAVLRSSIREYLCSEAMHHLGIPTTRALCVIGSDQPVRRETVETAAVVTRVAPSFVRFGHFEHFYSNDRTDALRALADHVIERFYPHCREADDPYLALLNEAVISTADLMVEWQAVGFCHGVMNTDNMSILGLTIDYGPFGFMDGFDAGYICNHSDSQGRYAYRMQPQIAYWNLFCLAQGLLPLLGEKHEESVRGDKAIEDAQRVLGGFKDRFAPALERRMRAKLGLETERAGDDALANRLFEVMHANRADFTLTFRNLARVSKHDASGDAAVRDLFLDRAAFDAWVNDYRARLSEETREDAARAIAMNRVNPKFVLRNHLAETAIRRAKEKDFSEVERLAAVLRRPFDEQPEHEAYAGLPPDWASSLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: AROA_STRMU
Sequence: MKLRTNASGLSGTLKIPGDKSISHRSIMFGSLAKGITKIYGILRGEDVLSTMQAFRDLGVEIKDKDDFVEIHGRGFDGLKSPKKALDMGNSGTSIRLISGVLAGQDFTVEMFGDDSLSKRPMDRVTVPLRQMGVQILGRTERDLPPLTMKGSKRLKPIRYELPVASAQVKSALIFAALQASGESVIIEKEKTRNHTEDMIKQFGGHLDVDGKEIRISGGQEFTAQNVIVPGDISSAAFWLAAGLIVSNSKLTLKNVGINETRTGILEVIEAMGGKVELSDRDDLAKAATLTVESSNLKGTEIGGDIIPRLIDELPIIALLATQANGRTVIYDAQELKVKETDRIQVVADALNAMGAKITPTDDGMIIEGKTNLHGAKVNTFGDHRIGMMTAIAALLVKEGEVELERAEAINTSYPTFFSDLERITNG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF11_BORBR
Sequence: MSKDDVIQMQGEVLENLPNATFRVKLENGHVVLGHISGKMRMHYIRILPGDKVTVELTPYDLTRARIVFRSK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT12_LEITA
Sequence: MRVLFLYGLCVRFLYFCLVLYFSPRLPSSGNRRCLYAICYMFNILWFFCVFCCVCFLNHLLFIVEGGGFIDLPGVKYFSRFFLNA
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion matrix, kinetoplast.
Protein: MNTP2_PSYCK
Sequence: MLEVLLLALALAADAFAASIGLGSTHKSDVNSQFMKMALLIGVYFGVAQGVMPLIGYALGSTMLGWFAEGASWVAFVILVALGIKMLYESRSVNNDETRINLSHKTLLSLAIATSLDAMGAGFTLNLLAVNAYLACLIIALTTAVLSVLGAYIGRKSGTWLGSWAEALGGLVLIAIGVNMVV
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP 2.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNPA_EDWI9
Sequence: MVKLSFPRELRLLTPNHFNFVFQQPQRAGTPQLTILGRMNSLGYPRIGLTVAKKHVKRAHERNRIKRLTRESFRLRQHSLPAMDFVVIVKKGVQELDNRALTEMLEKLWRRHCRQARAS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RECA_BRUMB
Sequence: MSQNSLRLVEDNSVDKTKALDAALSQIERAFGKGSIMRLGQNDQVVEIETVSTGSLSLDIALGVGGLPKGRIVEIYGPESSGKTTLALHTIAEAQKKGGICAFVDAEHALDPVYARKLGVDLENLLISQPDTGEQALEITDTLVRSGAIDVLVVDSVAALTPRAEIEGEMGDSLPGLQARLMSQALRKLTGSISRSNCMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGSIKERDEVVGNQTRVKVVKNKLAPPFKQVEFDIMYGAGVSKVGELVDLGVKAGVVEKSGAWFSYNSQRLGQGRENAKQYLKDNPEVAREIETTLRQNAGLIAEQFLDDGGPEEDAAGAAEM
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHO_SALCH
Sequence: MRVAKIGVIALFLLMAIGGIGGVMLAGYSFILRAG
What are the official names of this protein?
UPF0387 membrane protein YohO.
What is the protein family that this protein belongs to?
Belongs to the UPF0387 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: KAPB_YEAST
Sequence: MEFVAERAQPVGQTIQQQNVNTYGQGVLQPHHDLQQRQQQQQQRQHQQLLTSQLPQKSLVSKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQLDYGIQGDDPYAEYFQDF
What are the official names of this protein?
cAMP-dependent protein kinase type 2, PKA 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein: NU120_YEAST
Sequence: MACLSRIDANLLQYYEKPEPNNTVDLYVSNNSNNNGLKEGDKSISTPVPQPYGSEYSNCLLLSNSEYICYHFSSRSTLLTFYPLSDAYHGKTINIHLPNASMNQRYTLTIQEVEQQLLVNVILKDGSFLTLQLPLSFLFSSANTLNGEWFHLQNPYDFTVRVPHFLFYVSPQFSVVFLEDGGLLGLKKVDGVHYEPLLFNDNSYLKSLTRFFSRSSKSDYDSVISCKLFHERYLIVLTQNCHLKIWDLTSFTLIQDYDMVSQSDSDPSHFRKVEAVGEYLSLYNNTLVTLLPLENGLFQMGTLLVDSSGILTYTFQNNIPTNLSASAIWSIVDLVLTRPLELNVEASYLNLIVLWKSGTASKLQILNVNDESFKNYEWIESVNKSLVDLQSEHDLDIVTKTGDVERGFCNLKSRYGTQIFERAQQILSENKIIMAHNEDEEYLANLETILRDVKTAFNEASSITLYGDEIILVNCFQPYNHSLYKLNTTVENWFYNMHSETDGSELFKYLRTLNGFASTLSNDVLRSISKKFLDIITGELPDSMTTVEKFTDIFKNCLENQFEITNLKILFDELNSFDIPVVLNDLINNQMKPGIFWKKDFISAIKFDGFTSIISLESLHQLLSIHYRITLQVLLTFVLFDLDTEIFGQHISTLLDLHYKQFLLLNLYRQDKCLLAEVLLKDSSEFSFGVKFFNYGQLIAYIDSLNSNVYNASITENSFFMTFFRSYIIENTSHKNIRFFLENVECPFYLRHNEVQEFMFAMTLFSCGNFDQSYEIFQLHDYPEAINDKLPTFLEDLKSENYHGDSIWKDLLCTFTVPYRHSAFYYQLSLLFDRNNSQEFALKCISKSAEYSLKEIQIEELQDFKEKQHIHYLNLLIHFRMFEEVLDVLRLGHECLSDTVRTNFLQLLLQEDIYSRDFFSTLLRLCNAHSDNGELYLRTVDIKIVDSILSQNLRSGDWECFKKLYCFRMLNKSERAAAEVLYQYILMQADLDVIRKRKCYLMVINVLSSFDSAYDQWILNGSKVVTLTDLRDELRGL
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  NUP120 is involved in nuclear poly(A)+ RNA and pre-ribosome export, in GSP1 nuclear import, in NPC assembly and distribution, as well as in nuclear envelope organization.
What are the official names of this protein?
Nucleoporin NUP120, Nuclear pore protein NUP120.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Protein: RL17_OPITP
Sequence: MRHNKHRASLGVTVEHRRAMLSNLAAALITHGRIETTLVKAKALRPFVEKVITKAKQAAAKTDKKDALHLRRLAQSDVRDETAVTKLFNETYKEFANRNGGYTRIYKLGPQRIGDAAEMALIEFVKADDPGYKKSKGKKATKAKGKKAKATPAAEAAAAATTEAAPAEEKK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RECR_RICCK
Sequence: MNETNDIDQLIYLFSKLPGLGSRSARRIVLYLLQDKDVRLKSLINNLINIDKKIVKCEICGNMDTENICRICSSEYRDKSVIAIVETVAELWAMERSGNFKGLYHVLGYNLSAASRKNPSMLRLPELLTRCFAANIKEVIIATNSTLEGQTTAYFITEYLKEHPAKISRLASGIPIGGELDYLDEGTLSAAINLRQPFE
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.