PharMolix/UniProtQA huggingface dataset:
Protein: ATG8_COCH4
Sequence: MRSKFKDEHPFEKRKAEAERIRQKYNDRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSGENTFGEAL
What is the function of this protein?
Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation (PubMed:28800850).  With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton (By similarity).  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity).  Participates also in membrane fusion events that take place in the early secretory pathway (By similarity).  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).  Moreover not only conjugation, but also subsequent ATG8-PE deconjugation is an important step required to facilitate multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components (By similarity).  Autophagy is required for conidiation, aerial mycelial growth, and pseudothecia formation, but not for host invasion (PubMed:28800850).
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, cvt vesicle membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Note=Membrane-associated through a lipid anchor (By similarity). This association needs the 2 ubiquitin- like systems required for cytoplasm to vacuole transport and autophagy (By similarity). Localizes to both the isolation membrane (IM) and the vacuole-isolation membrane contact site (VICS) during IM expansion (By similarity). The IM is a membrane sac generated from the pre- autophagosomal structure that ultimately expands to become a mature autophagosome (By similarity).
Protein: APT_SOLM1
Sequence: MDLRQLIRDIPDYPKEGILFFDITPLLGDPDGFRRAIDLLAERFADSGATKIVAAEARGFIFGAALAYKMGLGFVPVRKPGKLPYKTVSVSYDLEYGSDTLCMHEDALLRDEKVLVIDDLLATGGTLSGVIDLVEHFGADIVGIGVVIELEFLNGKEQLRSYGCESILQIA
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OE66_NPVOP
Sequence: MGLITLILALIVVLFVCVFASNSSKPANNASFADNGAQRTAREFGPAARGGELLEFERWFKDTLATVFAQKAEKVANPTRAWNAETVFDNLSPWTSAADFGTVCHTLIGYCVRYNSPGDALHHSPDLANNLISGLRAICARLPDPPPHQQAPWGPVADWYHFTITMPEVFMTVTIVLDNTPHYDEAAALTRHWLALYLPTAVTSMGWHRTAGNAMRMGVPYAYGQLLRGYSAQQIAQEPGVQETLKTVAFPYVAAGNGLHPDSIYIDHLDVRAYGYLINSFFTFAYYTRLFGADVVNTEGLTRAIENVGSPEGVVVPGVMSRNGTLYSNVIGNFVDYPIAVHSADLSKVLTKLSDSYYGAVVGATTRLAYYEADPTNNTQAPLWTMTRRIWNRRARVINYNANTVMFESGIILQSLNGVLRVPSTTTSTQSFRPAVGKTALAKTRTAGAILVHARFAEMNNLQFKSCTLFYDHGMFQLYYNIGVEPNSLNNVNGRVVVLSRDTSVNTNDLSFEAQRLNNNNSSDGSAFNGVVCQRVPITNFNVPSLTVRSPSASVELVEQIISFQNMYTASAVACYKLNVEGHSDALRAYRINMDEVVYVTTGEGVKALFAYPWLMLKEDAAVVFMSANEDLVVPMSVINNAFSAIDEPGLQYAPVNCFLYGNGFRLNDSLANLQFQFEIIN
What is the function of this protein?
Component of the polyhedra envelope.
What are the official names of this protein?
Occlusion-derived virus envelope protein E66, ODV-E66.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae E66 family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: NAGB_STRS2
Sequence: MKIHVVNNQVEGATVALDILREKLNGGTKVLGLATGSSPLEFYRLIRESDLDFSDVTSVNLDEYVGLGEESDQSYIHFMKENLFNTKPFKQSYLPNGLATDVVAETERYNKILAEHPVDFQILGIGRNGHIGFNEPGAPFDGQTHLVELAPSTIEANARFFDNPEDVPKQAISMGIANIMAAKTIVLMAYGQEKADAIKATVEGAVTEDVPASVLQNHDNVILILDQAAASKLV
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: HXB1_PANTR
Sequence: MDYNRMNSFLEYPLCNRGSSAYSAHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQNSGYPAQQPPSTLGVPFPSSAPSGYAPAACSPSYGPSQYYPLGQSEGDGGYFHPSSYGAQLGGLSDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTAKVSEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREGGRVPPAPPGCPKEAAGDASDQSTCTSPEASPSSVTS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Acts on the anterior body structures (By similarity).
What are the official names of this protein?
Homeobox protein Hox-B1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Labial subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPC_SINMW
Sequence: MTDILRRIEAYKRGEIAAAKVRIPLAELKARIAEQSPPRGFRAALGAHREKGDFGLIAEIKKASPSKGLIRPDFDPPELAKAYAAGGAACLSVLTDAPSFQGAPEFLTKAREACPLPALRKDFMFDTYQVFEARAWGADCILLIMASLADDDARRLEEAAFALGMDVLVEVHDAEEMDRALRLSSPLVGINNRNLRTFEVDLAVSERLATMVSSDHLLVGESGVFTHEDCRRLEKSGITTFLVGESLMRKDDVEAATRALLTGSANILAAE
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: LYSY_PICTO
Sequence: MQVGIVGGSGYIAGQLLRMLAFHKDIEIKIVSSKSHAGEKLSRVHPDLLNILDLRFSDMDPVDLASRVDLVFLALPHGTSINYVPDIYEIGTKIIDMSADFRLKDPDLYREWYGFEHNYPDLLEKFVYGMPEFHRNEIKNSRYVSVPGCIASSTIYSVAPFSMLNLDNNIVTVDAKVGSSGSGSGTDSSKNYSERYNSVRAYKPVHHRHTPEIEQEIKYISGKNIKIAMSAHSVNMVRGILTTSNIFIDLDEPDALSQLREFYKNEKFIRLIFDRKSNFRYPDPKTVIGTNFADLGVISDGYIKRIVSLGAIDNMIKGAAGNAIQSMNIMNHFDESEGLLIPAAFPV
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1578_ARCFU
Sequence: MIFLIISVPFGIYSLVIYNLTRRAPGKMRYLIPPLLTATLPALYLPLTGFKVSYDLLPVVGYLTYSQFLLLLLQLQR
What are the official names of this protein?
Uncharacterized protein AF_1578.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCPR_CAVPO
Sequence: MGDSHVDTGATSTEAVAEEVSLFSMTDMILLSVLVGFLTYFFLFRKKKEEIPEFTKISTTTSSVKESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMAADPEEYDLADLSSLPEIDNSLAVFCMATYGEGDPTDNAQDFYDWLQETDLDLSGVKYAVFGLGNKTYEHFNSMGKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEATGEESSIRQYELVLHADTDPAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSNLVNQLGKILGADLDVVMSLKNLDEESNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEQLHKMASSSGEGKELYLTWVVEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETKSGRINKGVATSWLQAKDPAGENGRRALVPMFVRKSQFRLPFKSTTPVIMVGPGTGVAPFIGFIQERAWLQQQGKEVGETLLYYGCRRSDEDYLYREELAQFHKDGTLTQLNVAFSREQAQKVYVQHLLKRDQEHLWKLIHEDGAHIYVCGDARNMARDVQNTFCNIAAELGGMEHTQAVDYVKKLMTKGRYSLDVWS
What is the function of this protein?
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes.  It can also provide electron transfer to heme oxygenase and cytochrome B5.
What are the official names of this protein?
NADPH--cytochrome P450 reductase, CPR, P450R.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: TGT_MACCJ
Sequence: MNAVTYEHIKTCKQSGARLGIVHTPHGSFETPMFMPVGTQATVKTMSPEELKAMNAKIILSNTYHLWLRPGNDVIREAGGLHKFMNWDGPILTDSGGFQVFSLSDMRKIEEEGVHFRHHLNGSKLFLSPHKAMHIQNDLGSDIMMAFDECPPMPATYEYVKASIERTSRWAERCLEAHQRPEDQALFGIIQGGEYEDLRTQSAKDLVSMDFPGYAIGGLSVGEPKPIMYRMLEHTTPLMPFNKPRYLMGVGSPDALIEGAIRGIDMFDCVLPTRIARNGTCMTSKGRVVVKNAKYERDFTPLDEKCECYTCKNYTKAYLRHLIKADETFGIRLTTIHNLHFLLNLMEQVREAIRNDRLLDFKEEFFEEYGLNVENPKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: SMG_BORPA
Sequence: MFDILVYLFENYYTPQACPAADVLAKRLAAAGFEHEDIDDALGWLYGLAETTERCVELAHAPATGIRIYTDAEYQQLGTESIGFITFLESAGVLPAPLREIVIDRALASPETPISLSKIKIIALMVLWSQEAEIDNLVLEELLDDEGSRRLH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: RPOA_CAUVN
Sequence: MIERNWNELIRPEKPQIETGADATRKARIVAEPLERGFGVTLGNALRRVLLSSLQGAAVTAIQIDGVVHEFSSLEGVREDVVDIVLNIKQLAVRMHAEGPKRMTLRATGPGPVTAGQIETPADIEILNPDHVLCTLDDGASVRMEFTVNNGKGYVPADRNRPEDAPIGLIAVDALYSPVKRVAYRVEPTRQGQSLDYDKLILEVETNGAVTPVDAVAYAARILQDQLQIFITFEEPKAKSADESKPELPFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLAGMGLHLGMDVPNWPPENIEDLAKKFEDQI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: Y7KD_STRLI
Sequence: MIALAYLATVAIAAMVLAVALRRRPTPTNPPAPAPAPALAAVDGGAEIRVILAATHQLAARLSTAA
What are the official names of this protein?
Uncharacterized 6.6 kDa protein, ORF66.
Protein: MOBA_STAAW
Sequence: MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_STRT2
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKARYGGLGTQKAVDNVNNVIAEHIIGFDVRDQQGIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIVPAGAPTFKEALRWGAEIFHALKKILKERGLETAVGDEGGFAPRFDGTEDGVETIIKAIEAAGYVPGKDVFIGLDCASSEFYDAERKVYDYTKFEGEGAAVRTAAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGDKVQLVGDDFFVTNTAYLEKGIAEHAANSILIKVNQIGTLTETFDAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RSMJ_SALSV
Sequence: MQICLMDETGATDGALSVLAARWGLEHDEDNPMALVLTPQHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLTRGYADADIGPWLQQRLQLIHASSLTALTDITPRPQVVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVKRPDYAPPLADVATPNAIVTKGHRFDIYAGTPLTE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FYV10_DEBHA
Sequence: MSEPTVNFHIQTRLTEFKIPTELIKKNFKAVQKQIEKQKKSIGEDVAKVKKNNKLPTAMKIEMINKLIKSFEIFQKRLRTSINRDEVFRSRIIARLENLSELANYTVKTNVVLESNASPIDSDDNRDESSVTPKSMEDEDRPLDLHNVNLINWYRDQTNLLIIDYLIKSNTRSDQNIGLQLLKSISQTNPKFTKLIDYDLYDNFNKVFVSIIENHDLSLVIAWFNENRSFLKKANSNLEFEINYCKFLSLIEEGDVNEAIKFSQVNLSPYGNKGNYQSQEFMNHESNLNKLKEIGGLLVYMAINEKANAQIDKSIPFSSSLVINSPRFKEYKKLLSNERWDSLSQCFIENFTKLYGISRNYPLFIYLSAGLSSLKTKSCYCNTENTIFKQYEESSESNKNIYKKDLAVLTDKKYRGPNKYYKLLNKINHCPVCSPELYKLSKNLPYAQLITSIFNNPFKLPNGNIYPFDKLLNPSEKYLSEKNTLLRMGKIKDPLTREIFLIDDCVRVYPA
What is the function of this protein?
Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
What are the official names of this protein?
Protein FYV10.
What is the protein family that this protein belongs to?
Belongs to the FYV10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PALB_CANGA
Sequence: MNVDRCWEQYYKTLKLIYLEENKETCQREIDHLVDTAIELKEKTYSNAVLDLGRQFREVCPKARIMWKTSSIAGNFYPPISISDIYSPVIANVFDQTTRLECRRQEYSLRMPLQEEPNFTGIQQHAQVSDCSLVVSLININRYKTTMPVVKQVAENLYATNLYFNGAQRRLVLVSTENIPTMQDDPTKQMSVHSANKINKILELGLLKLTSLSYHSEGSNTAIDTYRLCGWIPDISSINEFNFLKVHKAFSRGECLIAMGTGGFVPKENIFGVKLRKYHDYAVLDIDMINEVVTLRDPLISDTLLTINFDSIRKYFLQVYCNWDSSKLFMFTKDTQIFYSDKKFNPYQTLAGKPTFYLKNNSDRDEYAWVLLEFHLDKNNNTTAYLQEIPDRISTVRLGYNDNSAETGFQLIKIRLKPKQCIWYFCYSSTDKMLTFHTYSTSSDVVFVRSKMPGCDFDVTECAILPENIVPMQYPNHSETDIYYLASIDFSIEGEPGITIITDMVVCLETDDDLVNFQMFHWDDLDFNSPIYDEFYMNERMFEKKDLPLTSGERYRIVASTARPPISKGYQCAVSGINIHADYPCSYKLRESDVRYNSMMFKLPHVFTLASTGITKISLVNRNKYNKVFMRIYPQTQEDYRYNYRVISADTGEDLVKPGNNIQKLYGGIVIKEFLVSDQTNLELHLSFQDNGRVPVELKCQLYVGSVKIITLS
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
Calpain-like protease palB/RIM13, Cysteine protease RIM13.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family. PalB/RIM13 subfamily.
Protein: MDCG_PSEPF
Sequence: MVNTPLAHDLLWGMTPAQLPADAPQWAIDSLAAGQPVVVRRALSEDGCVAVGVRGRFREQRLAAFMSVDSIACRVSPEALCQVESARDLPVMQALRQLRPVLDDCGWTWGVSGSVGFELASGFTAMHERSDLDLILRTPQLITRNQARKLVAYFEQAICRVDLQLQTPFGAVALREWAGNASRVLLKNAREACLVSDPWNPQEQAA
What is the function of this protein?
Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].
What are the official names of this protein?
Phosphoribosyl-dephospho-CoA transferase, Malonate decarboxylase holo-[acyl-carrier-protein] synthase, Holo-ACP synthase.
What is the protein family that this protein belongs to?
Belongs to the MdcG family.
Protein: UNG_ACIB3
Sequence: MQLTEQQQDKLSKVQLEESWKRSLTPFLLSPYMDSLRDFLFQQKQAQKTIYPPSKQIFNALNITPLDHVKVVILGQDPYHGPNQANGLSFSVQRGVALPPSLRNIFHELHTDLGVPISRHGDLTKWAEQGVLLLNSVLTVEAGQPTSHQKQGWEEFTDAVIDVLNEQREHIVFILWGAYAQRKGQRINREKHLVLTAAHPSPLAANRGGFFGCKVFSKTNQYLKQHGIEPIDWQLDA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO10_ARCFU
Sequence: MDVPRNENSSDFPIRCFSCGAVIGHLYDEYKQKLSEGKSPKEALDELGIERYCCRRMFITHKSVIKELSRFHGAVG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_STAAE
Sequence: MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YWBE_BACSU
Sequence: MNGQERNSISKGLQVDIVLKADQKTGKLTRGTVKDILTKSNFHPHGIKVRLEDGRIGRDQQIVST
What are the official names of this protein?
Uncharacterized protein YwbE.
Protein: RS2_CLOPS
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMAPYIFTERNGIYIIDLQKTVKKAEEAYNFIREVSEAGKDVIFVGTKKQAQEAVKEEAERSNMYFVNHRWLGGMLTNFTTIKTRINRLNKLDEMEQDGTFDVLPKKEVIKLKLEREKLQRNLGGIKELDASNIGAMFVVDPRKEKNAIAEAKILGIPVVAIVDTNCDPEEVDYVIPGNDDAIRAVKLIAGKMADAIIEGRQGEQLAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: DAPA_STAA2
Sequence: MTHLFEGVGVALTTPFTNNKVNLEALKAHVNFLLENNAQAIIVNGTTAESPTLTTDEKERILKTVIDLVDKRVPVIAGTGTNDTEKSIQASFQAKALGADAIMLITPYYNKTNQRGLVKHFEAITDAVKLPVVLYNVPSRTNMTIEPETVEILSQHPYIVALKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGTLLSALSVDINPIPIKALTSYLEFGNYELRLPLVSLEDTDTKVLREAYDTFKAGENE
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_LOBMA
Sequence: MAKGKDVRVTIILECTSCVRNDSKKELAGISRYITQKNRHNTPSRLELRKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: C19L1_XENLA
Sequence: MGERVLRVLTCGDVYGRFDVLFNRVRVIQKKSGQFDMLLCVGSFFGTSPESQTHWDEYKSGAKKAPIQTYVLGANNQETVKHFKDVDGCELAANITYLGRKGLFTGASGLQIAYLSGIESSSEPAPAYCFTAKDVTSLKMSLMSNSKFKGVDILLTSSWPKDVSNYGNALPNEASKKCGSALISNLAFNLKPRYHFAALEGENYERLPYRNHLVLQENAQHVSRFISLASVGNLDKKKYIYAFNIVPMSLTDIADLVKQPLDVTENPYRKSDKDTPKSKGNKSAEEEEPTQQFFFDLNKPQGKKRQTDGKGGRQSQAKQPRKHPQPTGPCWFCLASPEVEKHLVVSIGDNCYVALAKGGLMSDHVLILPIGHYQSTVDLSSDVVKEVEQYKAALRTFFKTKGKRYVMFERNYKSQHLQLQVVPLPLSCCTTEDIKETFILQAQEQGMELLEIPEHSDIKQIAQPGTPYFYVELDSGEKLFHRIKKHFPLQFGREVLASEAILNIPTRADWKDCKSSRAEEEDLTKTFRDAFEPFDFTLQD
What are the official names of this protein?
CWF19-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the CWF19 family.
Protein: CBIA_METBF
Sequence: MLNDKQSVENIPRILISADRSSSGKTTISMGLMAALVSRGYKVQPFKVALDYIDPSYHTEITGRFCRNLDGYLMDENGILDVYTHACEAGEKADIAIIEGVRGLYEGFESLSDLGSTAQIAKILNCPVIFVINARSITRSSAALINGYRNFDPDVEIAGVILNNIGSRRHAKKAKEAIEYYTGVPVIGIVPRDPAMQISMRHLGLMPALEGRRRLGDGGFEARLRGIEEIINKGIDVDRFMEIAKSAKALKSPENSVFSSVSDPGAPRPKIGVALDEAFNFYYRDNIDLLNLAGAEIVYFSPVKDASLPEVDGLYIGGGYPELFAAELEANESMRQDIKKASAAGMPIYAECGGLMYLTEKISTGVPGKGTYHDASMPESTYSMVGALPGHTIMGQTRVVSYNIGTLNKDCLLGKKYNSFKGHEFHHSEIREIPEDAEFAITLSRGTGIKNGMDGLISGNTLGSYAHLHGVAYREFASSLVEAARNFRDSRVLP
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source (Potential).  Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation (PubMed:28225763).  Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source (PubMed:28225763).  Also able to use sirohydrochlorin as substrate, but only produces a monoamide species in a much slower reaction (PubMed:28225763).  Unable to use other metallosirohydrochlorins such as sirohaem and Co-sirohydrochlorin (PubMed:28225763).
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase, Ni-sirohydrochlorin a,c-diamide synthase, Ni-sirohydrochlorin a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: RS27B_YEAST
Sequence: MVLVQDLLHPTAASEARKHKLKTLVQGPRSYFLDVKCPGCLNITTVFSHAQTAVTCESCSTVLCTPTGGKAKLSEGTSFRRK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S27-B, RP61, Small ribosomal subunit protein eS27-B, YS20.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.