PharMolix/UniProtQA huggingface dataset:
Protein: GCH1_SHEDO
Sequence: MALSDAAIKVQAALNERGLETPMLPKTSTPEERKIKIEHHMREILTLMSLDLTDDSLMDTPRRIAKMYVDEIFSGLDYDNFPKITVIDNKMGFDEMVRVQDISLTSTCEHHLVTIDGLATVAYLPRAKIIGLSKINRIVRFFAQRPQVQERLTQQILVALQTLLETKDVAVKIDAVHFCVKSRGVMDSTSSTTTTSLGGIFKSNPATRAEFLQQAKF
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GLK_ECO57
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What is the function of this protein?
Not highly important in E. coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate.
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_ECOHS
Sequence: MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKFRFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMVVRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQLLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: MQO2_STAAR
Sequence: MAKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPAIESSNERNNAGTGHAALCELNYTVLQPDGSIDIEKAKVINEEFEISKQFWGHLVKSGSIENPREFINPLPHISYVRGKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLMMKGREDNPGIMAASKIDEGTDVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNGQWEVTVKNRLTGEKFKQVTDYVFIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACTNPQVIEQHDAKVYGKEPPGTPPMTVPHLDTRYIDGQRTLLFGPFANVGPKFLKNGSNLDLFKSVKTYNITTLLAAAVKNLPLIKYSFDQVIMTKEGCMNHLRTFYPEARNEDWQLYTAGKRVQVIKDTPEHGKGFIQFGTEVVNSQDHTVIALLGESPGASTSVSVALEVLERNFPEYKTEWAPKIKKMIPSYGESLIEDEKLMRKIRKQTSKDLELGYYEN
What are the official names of this protein?
Probable malate:quinone oxidoreductase 2, MQO 2, Malate dehydrogenase [quinone] 2.
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: CU13_LIMPO
Sequence: GIFPYNVPEGQHDPAYLQALQQQALHYINLQQVPDLQLHRARELEVIAKNPTAYHPGYNYAGHYYPGNYYSGYYHPGHYYTALHHNAALHQHSLNEQKVINEQKALIAGQ
What are the official names of this protein?
Cuticle protein 13, LpCP13.
Protein: EIF3G_ASPNC
Sequence: MSKLGNRADWADDEEFDDPSALPPQQITTNKDGTKTIVSYRFNDEGKKVKVTRRIKTTVVREHVNPQVAERRSWAKFGLEKGNAPGPSFDTTSVGENIVFRPSVNWKLQAAEAEKNGGEKGSVKDQLKDKKVKCRICSGEHFTARCPFKDTMAPVDEPTAGGEAGDEDSPAAGALGAGTSSYVPPHLRKGAAGGGERMAGKYEKDDLATLRVTNVSELAEEGELRDLFERFGRVTRVFLARDRETQRAKGFAFISFADRSDAARACEKMDGFGYRHLILRVEFAKRAT
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit homolog, eIF3 p33 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MU117_SCHPO
Sequence: MWKFCCVTEKLTLFLFIYGICIYICIAVPIRSDLSTVFEPEAKGSRITSNYRRSLFNMLGYDNSVHPNNCKGSFLCPMLRGENRACPNAYMKYNRSLIYHGYSSYTASSCTAIYECEGDYPARTGNEIIDEFDQLNLQCSACGTRFFNNDNENTRCYVKLNYCYPDCTEITPSTSEYDYREPVRDW
What is the function of this protein?
Required for correct meiotic chromosome segregation.  Appears to also have role in sporulation.
What are the official names of this protein?
Meiotically up-regulated gene 117 protein.
Protein: YIP5_SCHPO
Sequence: MAHEIEIDSEADLGRTTFEAEDLYKQRTPITKPPAPRLQSRRASMQETPWTIKDSFNVETKDVVQRCIHTLIPTVNFFDVVDDRPDLYGPFWITTTVIQALFFSNSITEYARYATGHGTSGYSIKKLISAASIIYGYTTIIAVLLWGILVWNKCNPKLLDCLCLYGYANIVWLPVSLATPPFGLLSTLASHIVKYVLTGIGLLISIVFLTRNLYPICQQAGSNLCKLLLFGIIVFHCLLALSLQLIFFS
What is the function of this protein?
Possible role in vesicle-mediated transport.  May be involved in proper membrane localization of Rab GTPases (By similarity).
What are the official names of this protein?
Protein YIP5, YPT-interacting protein 5.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPD_RHDSA
Sequence: MSSKNVKVAKPYADAFIEIANKGSVINDLNCIATALSESKDLQKAIANPLVSSAAKKDIIKSIFAGNVDENTVKFMMVLCDRGRIEYLDAIAETALILAYKQASIEMAYVASSVKLSSAQTEALVDKLKAMTKADQIKLELKVDESLIGGFKVQIGSRIIDTSVQNQLKQLSSYLGASVA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, chloroplastic, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: IHFB_PARP8
Sequence: MTKSELVAQLATRFPQLVLKDADFAVKTMLDAMSDALANGHRIEIRGFGSFGLNRRPSRVGRNPKSGEKVLVPEKHVPHFKPGKELRERVDRNAGEPLKADAADDDL
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: DCD_PSEFS
Sequence: MSIKSDKWIRRMAQEHGMIEPFVERQIRGEGDERVISYGVSSYGYDVRCADEFKVFTNINSAIVDPKNFDEKSFVDVKSDVCIIPPNSFALARTVEFFRIPRDVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTTLPAKIYANEGVAQMLFLQSDEACEVSYKDRAGKYQGQRGVTLPRA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: SYA_ROSS1
Sequence: MKKLSSAAIREQFLRFFEERGHVRVPSSSLIPGNDPTLLFTNSGMVQFKDTFLGLEQRPYTRATTVQKCLRVSGKHNDLEEVGPSPRHHTFFEMLGNFSFGDYFKSEAIPMAWELLTKVFELPVERLWFTVFEGDDEVPPDDEAAQLWVAAGADPDRVLRFGRKDNFWVMADTGPCGPCSEITIYIGDDLRAMSAQGVNSDDPNYVEIWNNVFMQFERSTMQPLHRPSVDTGMGLERMAMVMQGVHSTYETDLFIPLIERQLALLGADESTYRARVAPYRAVADHSRAVAFLIADGVLPGNTGRSYVLRRILRRAVYQGRTVGFEKPFLAEIVAAVIEQMGAVYPELRERADFILETVDLEERQFLRTLSGGMSILNSVIERVRASGSTVIPGDDAFTLKDTYGFPLDLTQKIAAEHGLTVDEAGYERRMEEQRDRGRRAAQFKRAAEAEVWAGIDLPPTRFTGYAAVSGSGVVQAIVVAGDQVAEASAGQQVQIALDSTPFYAESGGQVGDTGVLIGPRGRVRVEDVQRPVPGVIVHYGVVESGSVMLHDPVDAHVDSGRRAAIMRNHTATHLLHRALRDVLGEHAAQAGSLVAPDRLRFDFTHTRPLTPEQLHEIERRVNAWIRADTPVVWQELSYQAAIEAGAIALFGEKYGDVVRMVTIGCVNGHDAPSPAALAERELAGFPMCSRELCGGTHVGRSGEIGLFRIISESSVAAGVRRIEALTGPEAEAWVDAQIATLQAVAARVGAPQTQLVERVEALIAELKQRQRALDELTARMARSNLEGLLASVQSVGDIRFLAAQVEAPNAARLREMGDWLRDKLGSGVVVLATVFDGKAQILAMATPDLAGKRIHAGNLVKALAPIVGGSGGGRPDMAQAGGRDSAKIPQALEHVAAVIAAQAGV
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT21E_HUMAN
Sequence: MIHFNLLETQLTPLASFQEIMKKTSIYHLPSFHYLMDSEAQEDTREAYDDKQVVTEIMARCFIPTLITTTSWESFHFIGHEIRITEAMDCYGAVVWPSALVLCYFLETNAKQYNMVDKNVIEIGAGTGLVSIVASLLGAHVTATDLPELLGNLQYNISRNTKMKSKHLPQVKELSWGVALDTNFPRSSNNFDYILAADVVYAHPFLEELLITFDHLCKETTIILWAMKFRLEKENKFVDRFKELFDLEEISSFPSLNIKLYKAVKKNRRSV
What is the function of this protein?
Protein-lysine methyltransferase.
What are the official names of this protein?
Putative methyltransferase-like protein 21E pseudogene.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL21 family.
Protein: RNY_LIGS1
Sequence: MIIAITILAIAIATLVIGFALGVAYRKRSYEQALDVATQTATGIIETAKKEAAASKKEAIIEAKEENHRYRSEIESELKERRSEIQRQENRLLQREEILDRKDTALDKREDVLEKKEAQLDSDQKVVTKQKEQASLLVKEQQDKLEEIAALTRPEAKELILNETKEELIHERAVMIKESEEETKATVDRKAKSLIAQAIQRSAADMVSETTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPVRREIAKMALERLIQDGRIHPARIEEMVDKATKDMDAKIREIGEEVIFDLGIHSMHPDLIKTIGRLNYRTSYGQNVLNHSIEVAKISGILAAELGEDVILAKRAGLLHDIGKAVDHEIEGSHVELGVELTKKYNESETVVNTIASHHGDTEPKSVIAVLVAAADAISAARPGARSESLENYIHRLEKLEDISNEFKGVQKSYAIQAGREVRVIVQPNEVSDLEATVLARDIRMKIEDELEYPGHIKVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RECA_RICPU
Sequence: MSNTDKERAIAAALAQIEKSYGKGSVMKLGQRPHVDIEAVSTGSLGLDIALGIGGVPKGRIIEIFGPESSGKTTLTLHLIAEAQKKGGTCAFIDAEHALDPAYAKKLGVNIAELIISQPDTGEQALEIADTLIRSSGIDMIIIDSVAALVPKSEIEGEMGDAQMASQARLMSQALRKLTASINRTNCITVFINQIRMKIGVMFGSPETTTGGNALKFYASVRIDIRRIGSIKDKEEVIGSQTKVKVVKNKVSPPFKTADFDIMYGSGISKEGEIIDLGVKLDIVEKSGSWFSYKNVRIGQGRENVKQYLKEHPQISNEIEKIIREKSSKITNINLDQTEEEND
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCMO_HELTU
Sequence: MDLLLIEKTLVALFAAIIGAILISKLRGKKFKLPPGPIPVPIFGNWLQVGDDLNHRNLTDLAKRFGEILLLRMGQRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRYGWEAEAAAVVDDVKKNPAAATEGIVIRRRLQLMMYNNMFRIMFDRRFESEDDPLFLKLKALNGERSRLAQSFEYNYGDFIPILRPFLRNYLKLCKEVKDKRIQLFKDYFVDERKKIGSTKKMDNNQLKCAIDHILEAKEKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQAKLRHELDTKLGPGVQITEPDVQNLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLGGFDIPAESKILVNAWWLANNPDQWKKPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKIDTDEKGGQFSLHILKHSTIVAKPRSF
What is the function of this protein?
Catalyzes the first oxidative step of the phenylpropanoid pathway in higher plants by transforming trans-cinnamate into p-coumarate (PubMed:8026495, PubMed:9398253, PubMed:14576280).  The compounds formed by this pathway are essential components for lignification, pollination, and defense against ultraviolet light, predators and pathogens (PubMed:8026495, PubMed:9398253, PubMed:14576280).  Can also use 2-naphthoic acid as substrate (PubMed:9398253).
What are the official names of this protein?
Trans-cinnamate 4-monooxygenase, Cinnamic acid 4-hydroxylase, C4H, CA4H, Cytochrome P450 73, Cytochrome P450C4H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYFA_DESRM
Sequence: MEQKLRTLAQEALAALESAKTPEALNDIRVKYLGKKGEVTQLLRGMGALSAEERPRVGQVANEVRASIEQALEERNARVKEAQKEQMLAAETIDVTLPGNQFGLGRMHPLTQVMQEIESIFMGLGFKIAEGPEVELDYYNFEALNLPKDHPARDMQDTFFINPEVLLRTHTSPVQVRTMEKMVPQVPIKIICPGRVYRRDDDATHSPMFHQVEGLVVDKHITFADLKGVLATFARQMFGLDTKTRLRPSYFPFTEPSAEVDISCFNCKGNGCRVCKGSGWLEILGSGMVHPRVLEMSGYNPEEVTGFAFGMGVERIAMLKYGIDDLRLLFDNDLRFLSQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUB_SHIFL
Sequence: MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVGRSGGGKSTLLHLLAGLETPTAGDVLAGTTPLAEIQDDTRMMFQDARLLPWKSVIDNVGLGLKGQWRDAARRALAAAGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRLEMQDLIVSLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKISLDLTVDIPRPRRLGSVRLAELEAEVLQRVMRRGHSEQLIRRHG
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KV5A1_MOUSE
Sequence: MHHTSMGIKMESQIQVFVFVFLWLSGVDGDIVMTQFAGVDGDIVMTQSHKFMSTSVGDRVSITCKASQDVSTTVAWYQQKPGQSPKLLIYSASYRYTGVPDRFTGSGSGTDFTFTISSVQAEDLAVYYCQQHYSTPPTFGGGTKLEIKR
What are the official names of this protein?
Immunoglobulin kappa chain variable 6-17, Ig kappa chain V-V region MPC11, Ig kappa chain V19-17.
Protein: AZUR_PSEAI
Sequence: AECSVDIQGNDQMQFNTNAITVDKSCKQFTVNLSHPGNLPKNVMGHNWVLSTAADMQGVVTDGMASGLDKDYLKPDDSRVIAHTKLIGSGEKDSVTFDVSKLKEGEQYMSFCTFPGHSALMKGTLTLK
What is the function of this protein?
Transfers electrons from cytochrome c551 to cytochrome oxidase.
What are the official names of this protein?
Azurin.
What are the subcellular locations of this protein?
Periplasm.
Protein: PURA_BURP0
Sequence: MSASAVNVTPGRNVVVVGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLIIGGKKTILRLIPSGIMREGVACYIGNGVVLSPEALFKEIGELEEAGLSVRERLFISEATTLILPYHVAIDQAREARRGAGKIGTTGRGIGPAYEDKVGRRALRVQDLFDARTFADRLRENLDFHNFVLTQYLGGAAVDFQATLDTMLGYADRLKPMVTDVSRRLYEENHAGRNLLFEGAQGTLLDIDHGTYPFVTSSNCVAGAAAAGAGVGPQKLDYILGITKAYCTRVGSGPFPSELYDADNPSRQDQIGITLANVGKEFGSVTGRPRRTGWLDAAALRRSIQINGVSGLCMTKLDVLDGLDEVKLCVGYKIDGEDVDLLPRGAAEVARCEPVYETFGGWKESTVGIDSWDALPANARAYLTRVQEVAGVPIDMVSTGPDRDETILLRHPFKV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH3A_MOUSE
Sequence: MAGSAWVSKVSRLLGAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEEASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
What is the function of this protein?
Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate.  The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitric dehydrogenase subunit alpha, NAD(+)-specific ICDH subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PBX2_HUMAN
Sequence: MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYEQACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN
What is the function of this protein?
Transcriptional activator that binds the sequence 5'-ATCAATCAA-3'.  Activates transcription of PF4 in complex with MEIS1.
What are the official names of this protein?
Pre-B-cell leukemia transcription factor 2, Homeobox protein PBX2, Protein G17.
What is the protein family that this protein belongs to?
Belongs to the TALE/PBX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_PSEMY
Sequence: MALAKRIIPCLDVDNGRVVKGVKFENIRDAGDPVEIARRYDEQGADEITFLDITASVDGRDTTLHTVERMASQVFIPLTVGGGVRTVQDIRNLLNAGADKVSINTAAVFNPEFVGEAAARFGSQCIVVAIDAKRVSAPGEPGRWEIFTHGGRKPTGLDAVEWARKMEGLGAGEILLTSMDQDGVKSGYDLGVTRAISEAVRVPVIASGGVGNLQHLADGILEGKADAVLAASIFHFGEYTVPEAKAYLASRGIVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_META1
Sequence: MVQDIFSKSAVASVKAQRISPRKARLVADLIRYKTATQALIILQTTNKKASGIILKLLNSAIANATNNNGLDATKLVVTEILVNDGPTLKRYQPHSRGRAYPILKRTSHFFIRVSEVSLPSVNEMTSKETVKEPAKKPSAKVEKPAEAKAPKQETSTKKPTTTTESKPKTSKAPAQKQAAKVAKPAAEDTKKPVKKSTTTTKSTKKEGSK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: QUEC_PROM9
Sequence: MTLKNKSIVVLLSGGLDSSTVTSIAKKSEAKIFGLSFDYGQRHKKELHSASTIAKHFDIQEFKIIKLDLSLWGGSSLTDTKKNIPTEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEQIIQLAMDNHVPLDKTWSCYSGDAKPCGKCDSCRIRNTAYKKWLNNKNKK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PHEB_CHRS2
Sequence: MLDAFSRVVTSADSKAAYVGGADLQALKKFVSEGNKRLDAVNAIVSNASCIVSDAVSGMICENPALISPSGNCYTNRRMAACLRDAEIILRYVSYSLLSGDSSVLEDRCLGGLKETYASLGVPAAGNARAVGIMKATCVGFINNTSNQKKLSTPAGDCSALASECAGYFDKVTSALA
What is the function of this protein?
Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.
What are the official names of this protein?
Phycocyanin PC645 beta subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: Y1543_HAEIN
Sequence: MSEKQINNFSLISRLFGNLFYRFPTDKVLADAFVWLQQEGLSQVWALDTDKESELALNSLQVKIDLNLLNEEYQKLFATNGKVMTAISAYGIDVEEFVNFRLVRNMPEVESADHFALLLLTASWLEDNSDSLVAQQEFFETFLLPCAAKFLTQVENQATLPFYRALALLTREILATMADELEEE
What are the official names of this protein?
Uncharacterized protein HI_1543.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family.
Protein: TIG_LISW6
Sequence: MSVKWEKQEGNVGKLTFDIEQEKVKEGLDRAFVKVRKTLNVPGFRKGKVPRQIFNQRFGEEALYQDALDILLPEVYSQAIDEAGIDPVDTPQVNIESMEKGETWVLTAEVTVKPEVKLGDYKGLEVEKRETELTTEELEAELKQLQERQAELVVKEDAPAENGDTVILDFEGFKDGVAFEGGQAENHSLELGSGQFIPGFEEKLVGLKAGDEADIELTFPEEYHAEDLAGQPVVFKVKLHEIKTKEVPALDDELAKDIDEEVETLDELKEKISKRLQEAKEESVAQAKQEEVIAKAVENAEVDIPHAMVHHEADHLMNHFAQDLQAQGLTPELYYQFTGQTEEAMHAQMETDAEKRVKMNLVLEAIAEAENIEPTEEAIDEEISTLAEKYGMEKDAVRAALGDMSELKSDLKIRKAIDVLLDSAVEK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CLPP3_PROMT
Sequence: MLPTVIEQSGQGDRAFDIYSRLLRERIIFLGTDVNDQVADALVAQMLFLEADDPEKDIQLYVNSPGGSVTAGLAIYDTMQQVSPDVITICYGLAASMGAFLLSGGTKGKRLALPNSRIMIHQPLGGAQGQAVEIEIQAKEILYLKETLNSLLAEHTGQNIQKISEDTDRDHFLSPQEAVEYGLIDKVVSNLNSI
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 3, Endopeptidase Clp 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_XYLFM
Sequence: MHITQLVLRHFRCFDVVDFFPLPGLNFFIGENGSGKTSLLEAVHLMGYGRSFRGRVRDGLIRHGSENLEIFVDWQETALINARRHRAGLSHYGQEWIGRLDGQKIIHLASLCAALAVITFESSSYQLINSNAELRRRFLDWGLFHVEPDFLDLWRCYTHVLKQRNSLLKQKEELAMLEAWDQKLSEVGEQLTFRRFQYLERLKQRVIPLISRITPNLKIHGFNFNHGWRRHELPLIDALFISRERDYQYGYTSLGPHRSDWTPQFSSIPGVHVLSRGQGKLITLMCLLAQAQDFFDQRGEWPILSLDDLASELDQKHQWRVLEMLAEIPAQVLITGTEIPQGLKPFFSVGAMFHVEHGAITRMF
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.