PharMolix/UniProtQA huggingface dataset:
Protein: ATG2_PICAN
Sequence: MAPQWMPQNIQKRLLKYILQQLSLFSEIDLPNLDVSLGTSSKVNLRNLELDIEKFSIPGMYMRSGSIETLSLSLTISDGVNVDCAGVNITLTPSLTPGKPNSTDQFSLAKSTADLANSVMFEDNVVEDEDIKETPSVDSNPLPPEIKDYRMSNMMAKAADMALSRLQLTVRDVKITMILETSHMEVCIEKVTLLSKEGTRYITVEGMTLNAIKPEVYSGEGVDNVDNSEERDETESEESEDYDDELMQTSFMADNKDDIHNSLMESMMFATQTSESVYMSATSNVFSSTTPRASTYENHQPSAVCVAYVSKCSVQFDGLQNIENMQVNLGRIKIAASPIPECLSSVIQSIRNLVRLSAMSTNETAGNTEKEPESDNTTLLNTLKIDEICVSFESALLKDGNFALDNTTCLSLSDIRFEQKNASFSFGSIAKIRLSRNDSKTELFCFDDSRAPNVADLGLEILNNDVSRITLICPKSLNIVVDEHLLTLAARYYSLMEPVIETLISVISTQTPYSYSNTHTSRFALHDTANNQKSNEFHAQTSSIHVKLQLNDFCITITISPITYDSQEGRFDTSSILFEYNDPTLGEQYASNQFLMISNLETSSAGVNKIRSFDSSSLQEIWLKTKIKTIVEKATLKLNFDVLIKIISSFGKLADLVRKSMVTSLPVARQKKVRMGSSLFLNATKMLKNCVEIKHCTIIFSHICPHFGDLKFSLKDIFVNFLQDGTLHSYVMSVLIQRICDSVHESLLEAADPRNKGYPMMFAKFKDNVGVHFKNCSFNYYGEWITLLESRERPREETNQSSSASSATSKKRQVNFTFADVSIGLVPVNLKSKIEVVIKKGIADLLIGTDGRSKLQSSFSSLTLLLIDDVANILSDKESKSLRHWINANNNHAIWTLNAILKSKGFVPVSYISSLFLNSTFESERHLEKRMTQAFSGQKIFASIDTKIHADALAVDLCADSCQCLIQTLKDLKQPVQFSFNEKYKPMTDEVDVFKDVDETTFSASVSVDVDNLEQTEIPENEKLEIVEDFFDKNLNSDSAEQSAIRSGSLSNSGTKSGAMSNIIFDDNHFGHSGEEFTTKVIPMAIGVSISNVTIKLYDGYDWKETQTTIKNAIRRVEDKAAKIGDNMNEVTEGSTSEHVRSVSNDSTELDTEAVNELLYESIHVGLLAGQDPQSFYDNINKSISNCGGSENVSEHNNLSPGSSSPASVNTANSTRSAASSHNIELGKVSSRRVRLKRSIYHKVLVELENLDLSNLTMVNSEPHPTKNSIVFSEDESKDDSELVSRMDLSVGSFKVVDNVPTSSWNMFVGYLREAGDKELGSSMLHAVIDTVRPVSSLAASELVISVSVLPLRLYVDQDTLDFLTRFGEFKDDRFTLPALDEEEVFIEKFQVNSVRIKLDYKPKKVDYAGIRSGHTNEFMNFFILDESEMVLKKLVLYGIPGFARLHKMLNDLWMPDIKRNQLGGVLSGLAPVKSIVKIGSGFKELVAVPLKEYEKDGRVIRGLQKGALSFAKITGGELLKFGVKLAAGTQTILESTEEALGGDGSAVRLPGYKKNTKSRRRTSPSEVIYATSRERSLFGHNTMSGAVFHRNSFDSYGEEEEFLEGAPALDGAGTQDAEQHQKSRFLVPAVFKSTAELPDVLESDSDLDDYYDESDNEGQKIVSLYSNQPENLNEGLQTAYTSLGRNLDTAREAIVSASTRAARSGSAQTAAREFAKATPIMVIRPIIGTTEAISRTLQGGINILDPEEKRRSEEKYKNTKKEAG
What is the function of this protein?
Lipid transfer protein required for autophagosome completion and peroxisome degradation and peroxisome degradation (PubMed:17204848).  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  ATG2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region.  The latter binding is assisted by an ATG18-PtdIns3P interaction.  ATG2 then extracts phospholipids from the membrane source using its NR and transfers them to ATG9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
What are the official names of this protein?
Autophagy-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: PGK_CLOPA
Sequence: XYNLLTIEDIDVKGKRVLVR
What are the official names of this protein?
Putative phosphoglycerate kinase, CP 11.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSM7_DICDI
Sequence: MTSSFNPKKESILDLQKFLGKEICVKFTGGREVQGILKGYDQLVNITLDQTQEFIRDAEDPLITTDEKRFLGLVVCRGSSVMMVCPTEGCEPIDNPY
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).  The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
What are the official names of this protein?
Probable U6 snRNA-associated Sm-like protein LSm7.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL28_METRJ
Sequence: MARRCELTGKAVQVGHLVSHSNRKTKCRFLPNLCNVTLQSDALGKRVRLRVTAHALRSVEHRGGLDAFLIKAGEGDLSQTARLLKREIHKKLAETPAAAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: UBID_HAES1
Sequence: MKYKNLRDFLELLEKQGELKRITQEIDPYLEMTEIADRTLRAGGPALLFENPKGYEIPVLCNLFGTPKRVALGMGQEDVTALRDVGRLLAFLKEPEQPKSFKDLWSTLPQFKQVLNMPTKVLSKAECQQIVFSDAEVDLYKLPIMHCWKDDVAPLVTWGLTITKGPSKKRQNLGIYRQQLIGKNKLIMRWLSHRGGALDFQEWKEARPNQPFPISVALGADPATILGAVTPVPDTLSEYAFAGLLRGNKTEVVKSISNDLEIPASAEIILEGYIDPTETALEGPYGDHTGYYNEQEYFPVFTVTHLTMRKDPIYHSTYTGRPPDEPAVLGEALNEVFIPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDINARDWKDVIWAITTRSDPARDCTIIENTPIDYLDFASPIAGLGSKMGIDATNKWIGETQREWGTPIKKAPNVVKRIDDIWESLNIFAPK
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FUCI_HAEIE
Sequence: MALATQSNRIKIGIRPTIDGRRMGVRESLETQTIRMAQSVAQLLQTHIRYTDSTFVECVVADSTIGGVAEAAACADKFKRENVGLTITVTPCWCYGSETIDMDPHMPKAIWGFNGTERPGAVYLAAALAGHSQLGLPAFSIYGTEVQEADDTNIPEDVKEKLLRFARAGLAVASIRGKSYLSIGSVSMGIAGSIVNQAFFQEYLGMRNEYVDMMEIKRRLDRKIYDQEEVDLALSWVKQYCKEGVDVNSLENQRNAEERAELWENVVKMTIITRDLMVGNPKLATLNYAEEALGHNAIAAGFQGQRHWTDHLPNGDFMEAMLNSTYDWNGVRPPYILATENDSLNAIGMLFGHQLTGKAQIFADVRTYWSQDSVERVTGWRPESGFIHLINSGSAALDGTGEHQDAQGNPTLKPAWDVTEEEAKRCLENTRWCPAVHEYFRGGGLSSQFLTKGGIPFTMHRINLIKGLGPVLQIAEGWSIDLPQDVHNKLNQRTNETWPTTWFVPRLTGKGAFTDVYSVMANWGANHCVATHGHVGADLITLASMLRIPVCMHNVSEKNIFRPSAWNGFGQDKEGQDYRACQNFGPLYK
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATXA_BACAN
Sequence: MLTPISIEKEHIRLINLLHFINEQNRWFTIKELSDYLQVADKTVRKYLKLLEDEIPPSWNLLVQKGKGIYLKKPLNESLSFVESKILRKSLNLQICEELVFKKNSMQSLAQKLHLQVGALYPIINQINYDIQSSHLNIKKKPLEISGREQDVRVFMLRLYCNIPNDYWPFPYINKQNITDLINKMEKILNVQMYTYSKHKLCVLFAITISRLLSGNTIDNVSGLILVNKNDDHYKTVASITSELQNSFGVTLHETEISFLALALLLSLGNSITTDSNKTLTSYKKTIMPLAKEITKGIEHKLQLGINYDESFLTYVVLIIKKALDKNFIQYYNYNIKFIRHIKQRHPNTFNTIQECISNLNYTVYSHFDCYEISLLTMHFETQRMLFKNNPKKIYVYTSQGCIHREYISALLEKRYNGLIKIVRNTIINLTNESLQDMEIDIIISNVNLPIKNIPIVQISEFPTERDFHEIKKII
What is the function of this protein?
Acts in trans to stimulate anthrax toxins expression.  It activates the transcription of the pagA, cya and lef genes.  It also activates capB, a gene required for capsule production.
What are the official names of this protein?
Anthrax toxin expression trans-acting positive regulator.
What is the protein family that this protein belongs to?
Belongs to the AtxA/AcpA family.
Protein: MNME_CYAP4
Sequence: MLNPGQTIAAIATAIVPQQGSIAIVRLSGSEAVAIAQRLFIAPGQQVWESHRILYGYVCNPRTGQRVDEALLLLMLAPRSYTKEDVVEFHCHGGMIAVQQVLQLCLEAGAVLAQPGEFTLRAFLHGRLDLTQAESVADLVGAKSPQAAQAALAGLQGKLIQPLQQLRRTCIDILAEIEARIDFEEDLPPLDLNQISSQIQHSLTEVNRILATADRGELLRTGLKVAIVGRPNVGKSSLLNAWSRSDRAIVTELPGTTRDVVESYLVVGGIPVQVLDTAGIRETSDQVEQIGVERSHKAAQAADLVLLVIDAQTGWTAEDQAIYTQVQERSLILVINKIDLVDQAFQPQACLPDPALTYLCTAAAQNQGIEDLESAILSKVQGGELEGANLDWAINQRQAAALTRAKLSLENVQETIANQLPLDFWTIDLREAIRALGEITGEEVTESVLDQIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGRG6_HUMAN
Sequence: MMFRSDRMWSCHWKWKPSPLLFLFALYIMCVPHSVWGCANCRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPELSAFTLCFEATKVGHEDSDWTAFSYSNASFTQLLSFGKAKSGYFLSISDSKCLLNNALPVKEKEDIFAESFEQLCLVWNNSLGSIGVNFKRNYETVPCDSTISKVIPGNGKLLLGSNQNEIVSLKGDIYNFRLWNFTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKAESNLSCGSYLIPLPAAELASCADLGTLCQATVNSPSTTPPTVTTNMPVTNRIDKQRNDGIIYRISVVIQNILRHPEVKVQSKVAEWLNSTFQNWNYTVYVVNISFHLSAGEDKIKVKRSLEDEPRLVLWALLVYNATNNTNLEGKIIQQKLLKNNESLDEGLRLHTVNVRQLGHCLAMEEPKGYYWPSIQPSEYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEANEVANQILNLTADGQNLTSANITNIVEQVKRIVNKEENIDITLGSTLMNIFSNILSSSDSDLLESSSEALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLPGTNAISNFSIGLPSNNESYFQMDFESGQVDPLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDARNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWITSFNVDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILKFCIIGWGLPALVVSVVLASRNNNEVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIVVMVQICGRNGKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRQHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNSHTDNVSYEHSFNKSGSLRQCFHGQVLVKTGPC
What is the function of this protein?
G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane (By similarity).  Couples to G(i)-proteins as well as G(s)-proteins (PubMed:24227709).  Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PubMed:24227709).  Regulates neural, cardiac and ear development via G-protein- and/or N-terminus-dependent signaling (By similarity).  May act as a receptor for PRNP which may promote myelin homeostasis (By similarity).
What are the official names of this protein?
Adhesion G-protein coupled receptor G6, Developmentally regulated G-protein-coupled receptor, G-protein coupled receptor 126, Vascular inducible G protein-coupled receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Detected on the cell surface of activated but not resting umbilical vein.
Protein: PDUO_MYCTO
Sequence: MAVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDGDVLWRPGGDRTAS
What are the official names of this protein?
Corrinoid adenosyltransferase, Cob(II)alamin adenosyltransferase, Cob(II)yrinic acid a,c-diamide adenosyltransferase, Cobinamide/cobalamin adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Cob(I)alamin adenosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_EDWI9
Sequence: MDPLIIKLGGVLLDNPQAMERLFQALLAYRHHDRRPIVIVHGGGCLVDELMVRLQLPVVKRQGLRVTPADQIGIISGALAGTANKTLQACAIAHGLAAIGLSLADGGAVQVSPLDASLGHVGQALPGSPLLLRQLLAADFLPIVSSIGISADGMLLNVNADQAATALAATLGADLLMLSDVSGILDGKGQRIAEMTAQKAQRLIEQGIITDGMVVKVNAALEAARTLGRPVDIAGWRHAEKLPALFNGEAVGTRIHA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_THEVO
Sequence: MDYVITTGKRKTAVARAVVKKGKGIITINGTPAELYPVEVLRNKILEPVKLAEDKAKGIDVTVKVKGGGVTGQADASRTAIARGIVKFLQDNELENLFRQYDRTLIVNDVRIKLPKKPGGRGARAKKQKSYR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MNME_SYNJB
Sequence: MDPTAPLADTIAAIATAVVPEQGSVGIVRLSGSRALPIVQAIFTPARRNAVWESHRLLYGWIRDEKGQILDEALAVWMQAPRSYTREDVAELHCHGGIMVVQATLQQCLRQGARLAQPGEFSLRAFLNGRIDLTQAESVADLVAARSPQAARMALAGLQGKLGGSIRALRQELLGLLAEIEARLDFEEDLPPLDVAAWQARLQAIQTQIQALLATAERGQLLRTGVKVAIVGRPNVGKSSLLNAWSGQDRAIVTDLPGTTRDVVESHLVVKGIPVQLLDTAGIRATEDPVERLGVERSQRLAQAADVLVLVIDAQAGWTAADAAIYESIRHRPLILVINKTDLAPPEGIPLPPEIAHRVPAVAAQGKGIPELEEALEQLVTQGRPQPNLEISLNQRQAAALQQAQASLEQVGQAIQAQLPLDFWSIDLRGALHALGQITGEEISESVLDQIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_BACVZ
Sequence: MPKGSGKVLSQNKKANHDYFIEETYETGIVLQGTEIKSIRAGRVNMKDSFAKIERGEVFLHNMHISPYEQGNRYNHDPLRTRKLLMHRKEINKLIGLTKEKGYSLVPLKLYLKNGFAKVLIGLGKGKKTYDKREDLKRKDAKREIERAFRDRQKGF
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: FCN1B_XENLA
Sequence: MTRWVQTFLLLVAVIRSYAEDSCPDVKVIGVGASDKLTILRGCPGIPGVPGPQGPSGPAGAKGEKGFPGIPGKMGPTGLKGERGISGPKGQKGDKGDPGIPVVGMAQNCKEWLDQGASISGWYTIYTTNGLSLTVLCDMETDGGGWIVFQRRMDGSVDFFQDWISYKRGFGRQDSEFWLGNNNLHLLTVTGSFQLRVDLTDFGNNRTSASYSDFRIAAEAQNYTLSLGTFTGGDAGDSLYGHKNKGFSTKDRDNDSSPASCAERYRGAWWYTSCHSSNLNGLYLRGNHSSFANGVNWKSGRGYKYSYEVSEIKFRPQP
What is the function of this protein?
May function in innate immunity through activation of the lectin complement pathway.  Binds to GalNAc and GlcNAc carbohydrate moieties.
What are the official names of this protein?
Ficolin-1-B.
What is the protein family that this protein belongs to?
Belongs to the ficolin lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUON_SALDC
Sequence: MTITPQHLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNQEEFYLLVLIASLGGILLTNANHLAALFLGIELISLPLFGLIGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGNLSFEALGKSLGDGMLHEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAVRVVLGIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPFRGPDADSLYSYRGLFWHRPVLAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQASLWWLVAAVVVGSAIGLYYYLRVAVSLYLHAPQQPGRDAPTNWQYSAGGIVVLISALLVLVLGVWPQPLISLVQLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOCD_ECO27
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGISDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COXX_KORVE
Sequence: MSSVTQPLAVPRPGVASLLRDYSELTKARVTTLIVMTAWTGAFFGAAKSGLPLVSWTLFHALLGIGLVSGGTAAMNEVIERESDARMRRTAIRPLVTGSMSLGHGMVVSLVMMIGGAGYLGLMTNWLTAALALMTSVVYLMAYTPLKKIHPICTTIGAFPGAMPPVLGWTAIRGHLGWEAVALFAILFFWQFPHFHSIAWLYRDDYANAGIRMLPVVERDGRSTAREIVIYAAFLLPITLTPFLLRFAGRIYFLAALVLGSMLFWVSLRMFTMNLAPSSPHSKKYARQLLLASVTYLPLLFAVMMLDRTI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y007_METJA
Sequence: MMKLKAIEKLMQKFASRKEQLYKQKEEGRKVFGMFCAYVPIEIILAANAIPVGLCGGKNDTIPIAEEDLPRNLCPLIKSSYGFKKAKTCPYFEASDIVIGETTCEGKKKMFELMERLVPMHIMHLPHMKDEDSLKIWIKEVEKLKELVEKETGNKITEEKLKETVDKVNKVRELFYKLYELRKNKPAPIKGLDVLKLFQFAYLLDIDDTIGILEDLIEELEERVKKGEGYEGKRILITGCPMVAGNNKIVEIIEEVGGVVVGEESCTGTRFFENFVEGYSVEDIAKRYFKIPCACRFKNDERVENIKRLVKELDVDGVVYYTLQYCHTFNIEGAKVEEALKEEGIPIIRIETDYSESDREQLKTRLEAFIEMI
What are the official names of this protein?
Putative dehydratase subunit MJ0007.
What is the protein family that this protein belongs to?
Belongs to the FldB/FldC dehydratase alpha/beta subunit family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Z_PARVP
Sequence: MGLRYSKAVKDKYGDREIEGRATMTLNLPQGLYGRFNCKRCWFATKGLIACSDHYLCLNCLTIMLSDGNFCEVCGKTLPKKIVFEESPSAPPYDG
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L.  Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z.  Also selectively represses protein production by associating with host eIF4E.
What are the official names of this protein?
RING finger protein Z, Protein Z, Zinc-binding protein.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae Z protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly perinuclear. During budding, associates at the inner side of the plasma membrane of infected cells.
Protein: RS12_NITOC
Sequence: MATINQLVRKPRVRQKQKSNVPALQACPQKRGVCTRVYTTTPKKPNSAMRKVARIRLTNGMEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGSLDTAGVGDRRQGRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: BTUD_ECOLI
Sequence: MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFATPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GUN4_ARATH
Sequence: MAGKSFMTPAIMLAMLLLISPETYAGHDYRDALRKSILFFEGQRSGKLPPDQRLKWRRDSALRDGSSAGVDLTGGYYDAGDNVKFGFPMAFTTTMMSWSVIDFGKTMGPELENAVKAIKWGTDYLMKATQIPDVVFVQVGDAYSDHNCWERPEDMDTLRTVYKIDKDHSGSEVAGETAAALAAASIVFEKRDPVYSKMLLDRATRVFAFAQKYRGAYSDSLYQAVCPFYCDFNGYEDELLWGAAWLHKASKKRVYREFIVKNQVILRAGDTIHEFGWDNKHAGINVLVSKMVLMGKAEYFQSFKQNADEFICSLLPGISHPQVQYSQGGLLVKSGGSNMQHVTSLSFLLLTYSNYLSHANKVVPCGEFTASPALLRQVAKRQVDYILGDNPMKMSYMVGYGSRFPQKIHHRGSSVPSVVDHPDRIGCKDGSRYFFSNNPNPNLLIGAVVGGPNITDDFPDSRPYFQLTEPTTYINAPLLGLLGYFSAHY
What are the official names of this protein?
Endoglucanase 4, Endo-1,4-beta glucanase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.