PharMolix/UniProtQA huggingface dataset:
Protein: NDHI_HUPLU
Sequence: MFSMVEGLQVYGQQTIQAAKYIGQGFMVTLDHMNRLPMTVQYPYEKLIPSERFRGRIHFEFDKCIACEVCVRVCPINLPVVDWEFEKNIRKKQLTSYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNHDQIALGRLPLSVVEDSTIRVISGLTKLPKGTMDGHSASKNVTNFLH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CRP_MESAU
Sequence: MEKLLWCSLVMIGFSQAFAQKDMSKTAFVFPKESANSYVSLEAQSKKTLKAFTVCLHIFTELSTTRSFSIFSYATKNSPNEILIFWSKDRGYAFGVGGPEVLFKASEIPEVPTHICASWESATGIAELWVDGKPKVRKILQKGYTVGTDASIILGQEQDSYGGGFDANQSLVGDIGDVNMWDIVLSPEQINTVCVGGTLDPSVLNWQALKYKVQGDVFIKPQLWP
What is the function of this protein?
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine.  Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity).
What are the official names of this protein?
C-reactive protein.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SL9A9_MOUSE
Sequence: MAGQLRFTSGKDEDHFQHQGAVELLAFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLILRYATAPTDIDSGTVYNCGNLFFSPSTLLVNITDQVYEYKYQREINQHNISPHQGNAILEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCVVIGLIMYGFVKAMVHAGQLKSGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLTYSISIYSPKENPNAFDTAAFFQSVGNFLGIFAGSFAMGSAYAVVTALLTKFTKLREFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKLRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDESLKEEPSSQQEANKLDKNMTKTESAQLFRMWYGFDHKYLKPILTHSGPPLTTTLPAWCGPVSRLLTSPQAYGEQLKEDDVECIVNQDELAMNYQEQSPSPSSPTTKLALDQKSSGQTPGKENIYEGDLGLGGYDLKLEQTRGQPQMD
What is the function of this protein?
Endosomal Na(+), K(+)/H(+) antiporter.  Mediates the electroneutral exchange of endosomal luminal H(+) for a cytosolic Na(+) or K(+) (PubMed:17005858).  By facilitating proton efflux, SLC9A9 counteracts the acidity generated by vacuolar (V)-ATPase, thereby limiting luminal acidification.  Regulates organellar pH and consequently, endosome maturation and endocytic trafficking of plasma membrane receptors and neurotransporters (PubMed:29362376, PubMed:24065030).  Promotes the recycling of transferrin receptors back to the cell surface to facilitate additional iron uptake in the brain (By similarity).  Regulates synaptic transmission by regulating the luminal pH of axonal endosomes (PubMed:29362376).  Regulates phagosome lumenal pH, thus affecting phagosome maturation, and consequently, microbicidal activity in macrophages (PubMed:35716776).  Can also be active at the cell surface of specialized cells, e. g. , in the inner ear hair bundles uses the high K(+) of the endolymph to regulate intracelular pH (PubMed:17005858).
What are the official names of this protein?
Sodium/hydrogen exchanger 9, Na(+)/H(+) exchanger 9, NHE-9, Solute carrier family 9 member 9.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein.
Protein: RIMM_SHEPW
Sequence: MSSKQEPVVLGKLGSSHGIKGWLKITTYTDSVEGIFDYSPWLLKEQGEWREVKVLQWRMQGKAVVACLEGVETRDQAQALTNCEIAVTPEQMEVLPEDEFYWRDLIGCEVVNTKGYNMGKVQEIVETGSNDVLLVKANAKDGFGKAERMIPFVTEQFIQKVDLTAKQILVDWDPDF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMBD1_REOVD
Sequence: MKRIPRKTKGKSSGKGNDSTERADDGSSQLRDKQNNKAGPATTEPGTSNREQYKARPGIASVQRATESAEMPMKNNDEGTPDKKGNTKGDLVNEHSEAKDEADEATKKQAKDTDKSKAQVTYSDTGINNANELSRSGNVDNEGGSNQKPMSTRIAEATSAIVSKHPARVGLPPTASSGHGYQCHVCSAVLFSPLDLDAHVASHGLHGNMTLTSSDIQRHITEFISSWQNHPIVQVSADVENKKTAQLLHADTPRLVTWDAGLCTSFKIVPIVPAQVPQDVLAYTFFTSSYAIQSPFPEAAVSRIVVHTRWASNVDFDRDSSVIMAPPTENNIHLFKQLLNTETLSVRGANPLMFRANVLHMLLEFVLDNLYLNRHTGFSQDHTPFTEGANLRSLPGPDAEKWYSIMYPTRMGTPNVSKICNFVASCVRNRVGRFDRAQMMNGAMSEWVDVFETSDALTVSIRGRWMARLARMNINPTEIEWALTECAQGYVTVTSPYAPIVNRLMPYRISNAERQISQIIRIMNIGNNATVIQPVLQDISVLLQRISPLQIDPTIISNTMSTVSESTTQTLSPASSILGKLRPSNSDFSSFRVALAGWLYNGVVTTVIDDSSYPKDGGSVTSLENLWDFFILALALPLTTDPCAPVKAFMTLANMMVGFETIPMDNQIYTQSRRASAFSTPHTWPRCFMNIQLISPIDAPILRQWAEIIHRYWPNPSQIRYGAPNVFGSANLFTPPEVLLLPIDHQPANVTTPTLDFTNELTNWRARVCELMKNLVDNQRYQPGWTQSLVSSMRGTLDKLKLIKSMTPMYLQQLAPVELAVIAPMLPFPPFQVPYVRLDRDRVPTMVGVTRQSRDTITQPALSLSTTNTTVGVPLALDARAITVALLSGKYPPDLVTNVWYADAIYPMYADTEVFSNLQRDMITCEAVQTLVTLVAQISETQYPVDRYLDWIPSLRASAATAATFAEWVNTSMKTAFDLSDMLLEPLLSGDPRMTQLAIQYQQYNGRTFNIIPEMPGSVIADCVQLTAEVFNHEYNLFGIARGDIIIGRVQSTHLWSPLAPPPDLVFDRDTPGVHIFGRDCRISFGMNGAAPMIRDETGLMVPFEGNWIFPLALWQMNTRYFNQQFDAWIKTGELRIRIEMGAYPYMLHYYDPRQYANAWNLTSAWLEEITPTSIPSVPFMVPISSDHDISSAPAVQYIISTEYNDRSLFCTNSSSPQTIAGPDKHIPVERYNILTNPDAPPTQIQLPEVVDLYNVVTRYAYETPPITAVVMGVP
What is the function of this protein?
Inner capsid (core) component.  Displays NTPase, RNA 5'-triphosphatase (RTPase) and RNA helicase activities and probably participates in transcription of the viral genome.  Helicase activity might be involved in unwinding or reannealing dsRNA during RNA synthesis.  RTPase enzymatic activity represents the first step in RNA capping, which yields a 5'-diphosphorylated plus-strand RNA.
What are the official names of this protein?
Inner capsid protein lambda-1, Lambda1, ATP-dependent DNA helicase lambda-1, Lambda1(Hel).
What is the protein family that this protein belongs to?
Belongs to the orthoreovirus lambda-1 protein family.
What are the subcellular locations of this protein?
Virion. Note=Found in the inner capsid (120 copies).
Protein: RS14Z_DESOH
Sequence: MARTSLVVKASREPKFSARKYNRCPICGRPRAFIRKFGICRICFRSMASMGKLPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RK32_PHAAO
Sequence: MAVPKKRTSMSKKHIRRNLWKKKGSLAAVKAFSLAQSISTGQSKSFFVAQKKVLEKS
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COF_ECO7I
Sequence: MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQIQLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: HIS4_LEGPC
Sequence: MLVIPAIDLQSGRCVRLKQGRFDQVTQFSVFPIERALHFAKLGAKRLHVVDLDGARSGKMQQLELICSMQKTGIPIQAGGGIRSIEQALECSSAGISQLVIGSLAITNTDLTIQIIEKIKPENIVLALDVRVDTKVPLLAINGWQNNSTSSLWEVVSYYENYGIKNILCTDIACDGMMNGPNFDLYQQAVEYFPQIAWQASGGIRHMQDITTLGSLGISAVILGLMLYQDNVSFEELLC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRAD4_MOUSE
Sequence: MPEAGFQATNAFTECKFTCTSGKCLYLGSLVCNQQNDCGDNSDEENCLLVTEHPPPGIFNSELEFAQILIIVVVVTVMVVVVVCLLNHYKVSTRSFINRPNQSQRQEDGLQPEGSLWPSDSSVQRPGASEIMCAPRGRDRFTTPSFIQRDPFSRFQPTYPYVQHEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTVFDSDLIDISMYNGGPCPPSSHSGISAATCSSNGRMEGPPPTYSEVMGHYPGTSFFHHQHSNTHRGSRPQFQPNNSEGTIVPIKGKDRKPGDLV
What is the function of this protein?
Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression.  In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor.  Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription.  Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.
What are the official names of this protein?
Low-density lipoprotein receptor class A domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the PMEPA1 family.
What are the subcellular locations of this protein?
Early endosome membrane; Single- pass membrane protein.
Protein: DUT_YEAST
Sequence: MTATSDKVLKIQLRSASATVPTKGSATAAGYDIYASQDITIPAMGQGMVSTDISFTVPVGTYGRIAPRSGLAVKNGIQTGAGVVDRDYTGEVKVVLFNHSQRDFAIKKGDRVAQLILEKIVDDAQIVVVDSLEESARGAGGFGSTGN
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RS18_LEUCK
Sequence: MSEQNSRPQNSERPQRSRRPQGGPRRRRKVDYIAANHIEFIDYKNTELLERFISERGKILPRRVTGTSAKNQRKVTTAIKRARIMALLPFVTED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HSF_YEAST
Sequence: MNNAANTGTTNESNVSDAPRIEPLPSLNDDDIEKILQPNDIFTTDRTDASTTSSTAIEDIINPSLDPQSAASPVPSSSFFHDSRKPSTSTHLVRRGTPLGIYQTNLYGHNSRENTNPNSTLLSSKLLAHPPVPYGQNPDLLQHAVYRAQPSSGTTNAQPRQTTRRYQSHKSRPAFVNKLWSMLNDDSNTKLIQWAEDGKSFIVTNREEFVHQILPKYFKHSNFASFVRQLNMYGWHKVQDVKSGSIQSSSDDKWQFENENFIRGREDLLEKIIRQKGSSNNHNSPSGNGNPANGSNIPLDNAAGSNNSNNNISSSNSFFNNGHLLQGKTLRLMNEANLGDKNDVTAILGELEQIKYNQIAISKDLLRINKDNELLWQENMMARERHRTQQQALEKMFRFLTSIVPHLDPKMIMDGLGDPKVNNEKLNSANNIGLNRDNTGTIDELKSNDSFINDDRNSFTNATTNARNNMSPNNDDNSIDTASTNTTNRKKNIDENIKNNNDIINDIIFNTNLANNLSNYNSNNNAGSPIRPYKQRYLLKNRANSSTSSENPSLTPFDIESNNDRKISEIPFDDEEEEETDFRPFTSRDPNNQTSENTFDPNRFTMLSDDDLKKDSHTNDNKHNESDLFWDNVHRNIDEQDARLQNLENMVHILSPGYPNKSFNNKTSSTNTNSNMESAVNVNSPGFNLQDYLTGESNSPNSVHSVPSNGSGSTPLPMPNDNDTEHASTSVNQGENGSGLTPFLTVDDHTLNDNNTSEGSTRVSPDIKFSATENTKVSDNLPSFNDHSYSTQADTAPENAKKRFVEEIPEPAIVEIQDPTEYNDHRLPKRAKK
What is the function of this protein?
DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription.
What are the official names of this protein?
Heat shock transcription factor, HSTF, Heat shock factor protein, HSF.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZEAYW_MAIZE
Sequence: MATKILALLALLALFVSATNAFIIPQCSLAPSAIIPQFLPPVTSMGFEHLAVQAYRLQQALAASVLQQPINQLQQQSLAHLTIQTIATQQQQQFLPALSQLDVVNPVAYLQQQLLASNPLALANVAAYQQQQQLQQFLPALSQLAMVNPAAYLQQQQLLSSSPLAVGNAPTYLQQQLLQQIVPALTQLAVANPAAYLQQLLPFNQLTVSNSAAYLQQRQQLLNPLEVPNPLVAAFLQQQQLLPYSQFSLMNPALSWQQPIVGGAIF
What is the function of this protein?
Zeins are major seed storage proteins.
What are the official names of this protein?
22 kDa alpha-zein 8, 22 kDa zein ZA1/M1, Zein-alpha ZA1/M1.
What is the protein family that this protein belongs to?
Belongs to the zein family.
Protein: DC1L1_DICDI
Sequence: MVEQQQQEEDIWGQILRESSNKNNYFEKRDVAILGDPTSGKSLLLSKFDTVSNVESLKSIALSYTFSDIYEDDTSEDPVGRINYWSLEGEASQNDLLKFSLNKENIKNCMVIITLDFSQPWNLVESLKKWLGILEEHIKSIFKDDKNGFKNLQDKLSIKWHEYEEPTTTAATTTTTTTSNNIENNTNKTSPTTDKIQTNNVQKKKKKKVNISSAEDASVLPPLSENILINNLGVPILVACCKSDSVVMLEKDFDYKDELFDYIQQYLRRICLQYGAGLIYTSARKEINCGVTLEYIENILFGFELKSKTQLIEKDQIFVPAGWDTLAKIQVDFENQKVCKDTDEPYENIVKKPSIIKRREQTQTNSIICDDDQDFLGKIKSQLDNDDQSSINSPSTPSPLSQSSNNNNSNNNINNTSTPSINTPLQPTDKPLSDIKSSNNPVAASPSAERAALANFFTSLISKDKTSSRKDLKSSLASPPTTSVSSNAREDAKKELDKLKQQKK
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  May play a role in binding dynein to membranous organelles or chromosomes (By similarity).
What are the official names of this protein?
Cytoplasmic dynein 1 light intermediate chain 1, Dynein light intermediate chain 1, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the dynein light intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ATPA_RHOPA
Sequence: MDIRAAEISAILKDQIKNFGQEAEVSEVGQVLSVGDGIARVYGLDNVLAGEMVEFENGTRGMALNLETDNVGVVIFGADREIKEGQTVKRTRSIVDAPVGKGLLGRVVDALGNPIDGKGPIQAVERKRVDVKAPGIIPRKSVHEPMATGLKSIDALIPIGRGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSVVVAATASDPAPMQYIAPFTGCTIGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDEQGNGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDAATQRLLNRGSRLTELLKQPQFSPLKMEEQVCVIWAGTNGYLDALPLNKVRAFEDGLLALLRGKESGILEAIRTSRDLSDDTAAKLKAVVESYAKTFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATG13_DEBHA
Sequence: MVSPGQNDLSSDKSQIDPFVKKQNAKLTQVIQNFFSKSVQIVLQSRIQSESHNKEEQLKVGGDVGGHNVSSKINKWFNLHMYNDNLPKEELKLWKNINDVSQMPPMIIEVYLDLRQLTAIQTVILRDDNGNPWTVAKGGSKKHEVVLERWLIEFDANTVSGTIVDELPLIYKQAIILFRSLYGYTRLMPTFKLKKNLNKSNLNIGCKILDGKQPISSKGRIGLSKSIIPHQMLTTESHMSHKHFLPIQTTLGTLKISIAYRNHHEFSIHDNEELLSTHFVNIDDNDKDSEITPVEIEFKEELKIDRDSTTNEKVNEPEDDESHHADVESSQEHLQSEEPDESFEQDAKHISGSRKKFSISNNASMSLSPCSSGPQTVTEDSPSHNKPSANTTPIVSQRPTINPFKVGSISTSPPATTNFGGSSLERKVSITSNKSASNASLAAMLRNPRSSTSSTNTTANIPIANNNSNNQYNSTFPRSVSSSHGSNLAHDNDNLLGFSNPDNTSNTPRFSSSFGSRASRRFSNTSGRQSSLPSGNMNDTSLLATSAGSASSDAPMSGLYIDDDIGDFVRMIDSKSDLRFSGYNSNNDSKISYNQGSNSQIDALNKFQMLKNQHQQLSDSVSASLILHHNQLSGSRPSSRKSSHSIHSPPPSLPSGSYDNSHLPSINSKLRENSSTSGNDDNLARDSGTPSSRKNSFDYSTNSNTTFLKSPITNKLVSSPVTSTTPIHSCLHKTNNESGVISGLATTPSIYNDRRQIHYESVFDDDDDDYANNTADNRDQDDSLKLYLTNKLANAPKSNTNSRSLKSSTNPPNIGEDDDDDDDDLLFTMSDMNLAKH
What is the function of this protein?
Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy.  Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation.  Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy.  Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity).
What are the official names of this protein?
Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Fungi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: RS16_CUPTR
Sequence: MVVIRLARGGSKKRPFFNIVATDSRSRRDGRFIERVGFYNPLAAEGEEGLRLAQDRLAYWQGVGAQLSPTVARLVKQGAKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RISB_CHLTR
Sequence: MKPLKGCPVAKDVRVAIVGSCFNSPIADRLVAGAQETFFDFGGDPSSLTIVRVPGAFEIPCAIKKLLSTSGQFHAVVACGVLIQGETSHYEHIADSVAAGVSRLSLDFCLPITFSVITAPNMEAAWERAGIKGPNLGASGMKTALEMASLFSLIGKE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: DER_NITOC
Sequence: MNALVALVGRPNVGKSTLFNRLTRSRDALVVDQPGVTRDRKYGLAHYGEQSFFVVDTGGVMEQESGIGRLMRAQAQLAIEEADVIFFLVDGREGLSSLDEEIAAWLRCAQKPLKLVINKAEGRDGDLVASEFYRLGLGEPIIISAQQGQGVGRLLEALLTLLPVLEREESEIQAKGLQFAVIGRPNVGKSTLVNRILGEERVLSSEIPGTTRDSISIPFRHHGKDYTLVDTAGIRRRSRILDKVEKFSVIQSLQSIAIAQVVILVIDAHDSVVEQDLHLAGVILESGKGVVIAVNKWDGLPLEQRQRVKTDLDRRLPFLVFARIHFISALHGSGVGDLFPSIDEAYQSANSHLPTGELNRALLAAVEKYPPPVVKGRRIKLRYAHQGGQNPPKIIIHGNQAEAVSANYRRYLINYFRNAFGLMGTPIALEFRTVKNPFKGRANILTQRQQQKRKRLVRFRKGRD
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CR3L4_MOUSE
Sequence: MELGCPELLEPPEDIFSTGSFLELGFNGPASKVPVTRGLQKSEPDDFLNLFIDPNMIHCSETSPGRDSGVSEDPGSPAQQASSSPALYEVVYDSGTLQGTQREAGPTFGLISIQIDQWTPALMVPDACTVSGLPSDSHRHILPRVSTRAPAPPAAMPSCQHHLFLTDEEKQLLAQEGITLPSHLPLTKAEERILKKIRRKIRNKQSAQDSRRRKKEYLDGLESRVAACSEQNQKLQRKVQELERQNIFLMEQVRQLQKLTAQTSSRAAQTSTCVLILLFSLALIILPSFSPFQGQSEARPEDYQLHGVISRNILTHENVTENLESPVLKSKLEELPEAPTTNGSTKTHLKMRVKARPPGQIRGMVHTDEM
What is the function of this protein?
Transcriptional activator that may play a role in the unfolded protein response of the testis.  Proposed to be involved in spermiogenesis.  May be involved in regulating the maturation of sperm head nuclei.  Alternatively proposed to be a paternally delivered transcription factor that may function in early zygotic gene activation.  Increases the binding of CREM isoform Tau with CRE.  The CREM isoform Tau-CREB3L4 heterodimer functions through CRE but not through UPRE and may recruit HIRA to CRE to regulate histone exchange.
What are the official names of this protein?
Cyclic AMP-responsive element-binding protein 3-like protein 4, cAMP-responsive element-binding protein 3-like protein 4, Attaching to CRE-like 1, ATCE1, Acre1, Transcript induced in spermiogenesis protein 40, Tisp40, mJAL.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type II membrane protein. Note=According to PubMed:16925989 is not observed within nuclei of haploid spermatids at any spermiogenic stage. SUBCELLULAR LOCATION: [Processed cyclic AMP-responsive element-binding protein 3-like protein 4]: Nucleus. Note=Under ER stress the cleaved N- terminal cytoplasmic domain translocates into the nucleus.
Protein: Y1175_LEGPL
Sequence: MPSFDIVSKMNEVDLRNAVDNAVREVSTRFDFRGVEATIELKDLTVTLRSESDFQVRQLEDLFRNHCSKRNLSTSGVDIEDEPVHSGKFYTLTMTFKQGIDQPTAKEIVKYIKETKAKVQTSIQGDKVRVTGKKRDDLQETIALLKKSNIELPLQYENFRD
What are the official names of this protein?
UPF0234 protein lpl1175.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: NUDI_ECOSE
Sequence: MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVESGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSANREVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: GCSPA_BACAA
Sequence: MLHRYLPMTEEDKKEMLQTIGVQTIDELFSDIPESVRFKGDLKIKEAKSEPELLKELSQMASKNANLKEYASFLGAGVYDHYAPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMDVANSSMYDGGTALAEAAMLAAGHTRKKKILVSSAVHPESRAVLETYAKGQHLEVVEINHKDGVTDLDVLQSEVDDTVACVIVQYPNFFGQVEKLADIEKIVHQQKSLFIVSSNPLSLGALTPPGKFGADIVIGDAQPFGIPTQFGGPHCGYFATTKAFMRKIPGRLVGQTVDSDGKRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVAMTALGKQGVKEMARQNISKAQYAKRQFEAKGFTVTFAGPFFNEFVVDCKRPVKEVNDALLQKNIIGGYDLGRDYKEHENHMLVAVTELRTKEEIDTLVNEMGAIQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: YR387_MIMIV
Sequence: MDKKTWVYIIIAIIIILLLVWYFRNHMSDQKGVNVNNQTYNMLQQQISSLNQQILFLKQQISNLHVPAPTSTVNSLRQTVSDINQQVSTINNQISSLNPYLPRNQQLELASVLSIFNRNALDLNNISRSVINRDINYFNAGQHGSQVPQNSHTVQNPNVADNELNVLQQKVDNLNGVVSNIRQHLAQFGSGIPESFRDEAEKAASYLNDRIDDINKNLPNLVQRLNPNQRNNLNRILSELNNDLSSLKNSLGSAVRNRINSVNIH
What are the official names of this protein?
Uncharacterized protein R387.
What are the subcellular locations of this protein?
Host membrane; Single-pass type II membrane protein. Virion.
Protein: Y587_METJA
Sequence: MVNEYKAHSSFILKVVITLIGYWIASILAIIIYSMFFKIETNTFLLCLLLPTPIIWFNILIGMGLTYRCMENLTIYDKHKLWCVFVRDLTLTILATILATLTTMELYQIEHPLKPIEFVFIVGLVLIVGFTIITTLIIKYLKIIKNLKKISKN
What are the official names of this protein?
Uncharacterized protein MJ0587.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0129 and MJ0554.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.