PharMolix/UniProtQA huggingface dataset:
Protein: NOLA_BRASN
Sequence: MTKATPRRRRWRIGELAGATGVTVRTLHHYEHTGLLAASERTDGGHRMYDRESIQRVHQIRALRELGFSLQEIRRAMDGRTSLTDLLRKHLQRIEVQVARATQLRDRLRNMTTDGDVRVSVDQLPAALDAMSKVEKRPQPRPCTCALAADREERWRRIRNDLRHCMDRNEHPCSDRTKAVALEARTLISEIAGNDLTGSTILKVLARLSDPRSLAGWDPHLMQYLDSALVALGDQPH
What is the function of this protein?
Involved in genotype-specific nodulation of soybeans.
What are the official names of this protein?
Nodulation protein NolA.
Protein: ER10A_ASPFC
Sequence: MAIQTTTGLAARLVAKRATFPASRRNFSASRSALKEIQEAYILSGARTPTAKFNGSFVSVSAPELGAVAIKSAVSKSGVPVEKITDVYMGNVLQGAVGQAPARQASMFAGLSPTVESMTVNKVCASGLKAVALAAQNIQLGLAEAQVAGGMENMSRVPYYLPRSTQLPPFGEIKLQDGLIQDGLWDVYNQFHMGICAEKTAKKYEISREEQDQYAIQSYQRAQAAWKENKFAEEIAPVTVKGKKGETVVERDEGYENLRIDKMATLKPAFLRDGTGTVTAGNASTMNDGASALVLGSKAIAREFAQGNRALARIVSTADAAIDPVDFPVAPAKAVPIALERAGITKDQVAVWEFNEAFAAVIKANEKILGLQNARVNPLGGAISLGHALGSSGSRILVTLLHQLQPGEYGVAAICNGGGAATAMVVQKLDRVD
What is the function of this protein?
Mitochondrial acetyl-CoA acetyltransferase that catalyzes both the formation and degradation of acetoacetyl-CoA (PubMed:32005728).  Has no overlapping function with erg10B and seems not to be involved in ergosterol biosynthesis (PubMed:32005728).  Plays an important role in growth, morphogenesis and maintaining mitochondrial function including the response to oxidative stresses (PubMed:32005728).
What are the official names of this protein?
Acetyl-CoA acetyltransferase erg10A, mitochondrial, Acetoacetyl-CoA thiolase erg10A, Ergosterol biosynthesis protein 10A.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DEOB_STRMU
Sequence: MSTFNRIHLVVLDSVGIGAAPDANNFSNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRDTPLKTVPAENHPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEIISKIEKFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDVIPLDELYRICEYARSITLERPALLGRIIARPYVGKPRNFTRTANRHDYALSPFAPTVLNKLADAGVSTYAVGKINDIFNGSGITNDMGHNKSNSHGVDTLIKTMGLSAFTKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMKVDDLLLITADHGNDPTYAGTDHTREYVPLLAYSPSFTGNGVLPVGHYADISATIADNFGVDTAMIGESFLDKLI
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_DEHMC
Sequence: MALPKRRLSHSRQGNHRAHVALTAPAVMECPQCNSPKLSHQACSVCGTYNGRTVIDMEAIAKKKADKSKGQQ
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: TEG4_HHV11
Sequence: MELSYATTMHYRDVVFYVTTDRNRAYFVCGGCVYSVGRPCASQPGEIAKFGLVVRGTGPDDRVVANYVRSELRQRGLQDVRPIGEDEVFLDSVCLLNPNVSSELDVINTNDVEVLDECLAEYCTSLRTSPGVLISGLRVRAQDRIIELFEHPTIVNVSSHFVYTPSPYVFALAQAHLPRLPSSLEALVSGLFDGIPAPRQPLDAHNPRTDVVITGRRAPRPIAGSGAGSGGAGAKRATVSEFVQVKHIDRVGPAGVSPAPPPNNTDSSSLVPGAQDSAPPGPTLRELWWVFYAADRALEEPRADSGLTREEVRAVRGFREQAWKLFGSAGAPRAFIGAALGLSPLQKLAVYYYIIHRERRLSPFPALVRLVGRYTQRHGLYVPRPDDPVLADAINGLFRDALAAGTTAEQLLMFDLLPPKDVPVGSDVQADSTALLRFIESQRLAVPGGVISPEHVAYLGAFLSVLYAGRGRMSAATHTARLTGVTSLVLAVGDVDRLSAFDRGAAGAASRTRAAGYLDVLLTVRLARSQHGQSV
What is the function of this protein?
May participate in DNA packaging/capsid maturation events.  Promotes efficient incorporation of tegument proteins UL46, UL49, and US3 into virions.  May also play a role in capsid transport to the trans-Golgi network (TGN) (By similarity).
What are the official names of this protein?
Tegument protein UL21.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae UL21 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.
Protein: KPRS2_STRPQ
Sequence: MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACQRASANTVNIVLPYFGYSRQDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAERYSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSGKKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIVTDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Putative ribose-phosphate pyrophosphokinase 2, RPPK 2, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 2, Phosphoribosyl diphosphate synthase 2, Phosphoribosyl pyrophosphate synthase 2, P-Rib-PP synthase 2, PRPP synthase 2, PRPPase 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYA_SERS3
Sequence: MELPLGSDLARLVRVWRALIDHRLKPLELTQTHWVTLHNIHELPPGQSQIQLAKAIGIEQPSLVRTLDQLEDKGLITRHICVHDRRAKRIMLTDMADPIIQAVNDVIDQTRSEILNGITPEEVSELATIISRLESNILSLYEMQS
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes (By similarity).  Participates in transcriptional activation of pig (prodigiosin pigment) and car (carbapenem antibiotic) gene clusters (PubMed:9402023, PubMed:12519208).
What are the official names of this protein?
Transcriptional regulator SlyA, Regulator of antibiotic and pigment protein, Rap.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: GLMU_RHOP5
Sequence: MTSRTSLTIVLAAGEGTRMRSSLPKVLHQVAGETLLAHVLKAAPEGDGAALAVVIGPDHQAVAEEVGRVRPQATTYVQRERLGTAHAVLAAREAIAAGADDLLVAFGDTPLISAATFARLRQPLAQGVALVALGFRPADPTGYGRLLVQNDRLVGIREQADASADERAIGLCNAGVMAIDGKAALRILERIGSANAKGEYYLTDAVAIARELGLEAAVIETSEDEVRGINTKAQLAEAEAVMQARLRQAALDAGVTMIAPETVFLAADTTFGKDVTIEPFVVIGAGVSIGDGAVIHAFSHLVQAKIGKNASVGPYARLRPGTSLGDGAKIGNFVETKAAQIDPGAKVNHLTYIGDAHIGPNANIGAGTITCNYDGFGKHKTEIGAGAFVGSNSSLVAPLKIGAGAYVGSGSVVTRDVPDDALAVERNQQKVSEGWAKRFREAKTRGKTRPAK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF3_AGRST
Sequence: MPRSRANGNFIDKTSSIVANILLRIIPTTSGEKKAFTYYRDGMLAQSEGNYAEALQNYYEATRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAILQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITKRFEFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CAS4_RHORT
Sequence: MAPSDTPPSAEDLPSQGELALFAPPATAEDALVPASMVNAWIYCPRLAVLEWGRGEKARSVDLIAGLRAHQATESGPTPALPDPMVLREDQSLKTRKLSLSSERLGLTAELDLLDVEEGVVIPVEIKVGKRPSVDEGAYLPERAQVCAQALLLREAGYTCLEGALWFAESRERVTVDLTEALVTATLVATSDLRLTVASGRLPPPLDHSAKCPRCSLLPICLPDEIAWFRKGSIARTPPPPASPALPLYGQTPGARIGKKDRGGSVCLDRMAAWLSSRPVPCYAAIGMLNTASGASHPSVARHADGGASARSFRLPTAFRRPVRRSLPCYAAR
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  This may be a 5' to 3' ssDNA exonuclease (By similarity).
What are the official names of this protein?
CRISPR-associated exonuclease Cas4.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated exonuclease Cas4 family.
Protein: COAD_STRPC
Sequence: MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKKSYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEENLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMNEKT
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_MARN8
Sequence: MAKKIEAYIKLQVAAGQANPSPPVGPALGQRGVNIMEFCKAFNAKTQGMEPGLPIPTVITVYSDRSFTFITKTPPAPVLLKKAAGIKSGSGRPNTDKVGTVTRAQLEEIAKTKEPDLTAADMEAAVRTIAGTARSMGLNVEGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL19_DESDA
Sequence: MDIIKKIERENMRLDVPAFRSGDTVKVHLRIVEGEKQRIQIFQGNVIRVKRGTTCATFTVRKISDGVGVERIFPLNSPFIDRVEVVTQGRVRRSRLYYLRALKGKAARIKPRGRF
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RS6_NITOC
Sequence: MRHYEVVFLVHPDQSEQLSAMMDRYRQIIETDGGCIHRLEDWGRRQLAYPIQKLYKAHYVLMNIECTPRTIEELTSAFRFNDAVLRDMVIRREEAITETSPLAKGEESGGRGYDSARSGRDRDESGGRGYDGARPGRDEDESKENTDRDEQSEDSE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: THIM_CERS4
Sequence: MDGCGTYLDTMRREAPLVQCITNFVAMNVVANVLLAAGASPAMVHDAEESGEFAAIAQALTINMGTPSPRWVEGMEAAARGAAAAGRPWVLDPVAVGATAFRRGLGARLLALKPTVIRGNASEILALAGAETRGKGADSADPVAAAEAAAQRLAESSGAVVAVTGPVDFVTDGRRGIRCANGHPLMPRVTALGCSLTGIVGAFAATRPPFEATAAALAFFGLAGEEAAKTATGPGSFQVAFLDALHTLSPEALDRGARLEAA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: YCIB_HAEIN
Sequence: MKQLLDFIPLILFFITYKLGGVREAAIVLVVATILQIVILKWKYGMVEKQQKIMASAVVFFGLLTAYFNEIRYLQWKVTIINGLFAIVLLVAQFQFKTPLIKKLLGKELQLPEKAWNTLNFGWAIFFIICMLVNIYISHNMSEEAWVDFKSFGIIGMTVIATIISGVYIYRYLPKDGSNSKDGEK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTS2_TREDE
Sequence: MTEHTLEVLQFSRIREIIASYCVTDEGKEFCLKKNPDTDIKKIEEEKKLGIDFLSLLRAYKAPPIKYRPPVLPFLEGIEVEGAALDIEGVYSVGLLALSVFSLHEWLSPFLENEDLNENSIVSFVKKIPDMLHLKNLVFSFIDENGELQDLPSLRAIKNKIRSIEDDIDKTMRNYFTNDATRQMLQSNLPTVKDGRQVIAVRSNFKGRIPGIIHEYSQSGQTFYLEPEEIVLKNNDLIAAHAEYERELLRLLQDLTSQIAEHTENIKEACEAITKLDCVAAASRWAHSNNCVFAGSIDLGLSHSIDKDGSHDSKGTPLAFYLHQARHPLLGKSAVPIDLKLSKDDRVLIITGPNTGGKTVSLKTAALFALINQTGWPVPAGPLTRLPYFDFIACDIGDEQSMDQSLSTFSAHMKNVSEIIRRAGDKSLIILDELGSGTDPQEGCAIAMAVLDDLLEKKAFVFVTTHHGALKNYGYSKESCVNASVEFNQNTLSPTYRILMGVPGESHAVDIAKRNGLPEHIIEKAHTYLGNNRADVSDLIKGLIQKHEDLNEFELQKKEEELKLKEDRRRSDLKELQLKQKELELKKDGIKRLDLFFEEKRKFLENLVRELREGELSREKTLSVKKWIDDFEKDLDKEHEALKLEQTKIDERLHSSKEKNKAPQNPELREGTRVIIKSLNRNGELIREEKKGKWLVAVDNLKLTIAEDDIEVCENQEKLKLSKPIVSIISDTSAPSSRPSFELRLLGMRAEEAQKALQDQMDLALVHGITEFAIIHGKGHGILQELSHDFLKRSPYVKAFRFAKPEEGGSGKTIVSLG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: YR883_MIMIV
Sequence: MTTTNNVLLVDDQHRNIGVTDDLHTIESLKSELTLDYDLPTLCGKNLDSPNILLNSIEKFKETFNKHYPFLEKINMKNLLIAGGSVSNIVRNKFQYGSDIDFFIYGLNQQEASSRVRQWLIDILVKKPDNSSEKTTTKKIDMTKYYKIIRNNNCITILLDHGDLKLQLIFRLYQSISEILHGFDLGSSAVGYDGENVYFTTLGKYCHEYSCNVIDTTRRSTTYEYRLNKYFDRGFNIVVPKLDLSKLKTFNLKYGEVEICELPYFIFSYQNIIGNKIIVKKFYDKYNIKSDYGLEPINSTNLYYQSLKINIGNLINDVDYYYYVSSHIDKQNTDILTKAPRLTKGDIITFYDGVRTKLNGKNIDVCLIRKYITIDTIENIVATMFHKDTNVKEYFDSIIEKQKELALNKLDILLQKNHNIVWITENPGKQLTSSFNPIIEVESKWYGEFYKE
What are the official names of this protein?
Uncharacterized protein R883.
Protein: RSMJ_VIBPA
Sequence: MQLQLICEDPSQQSHLDELAARWQLSHTDESDFALVLTAERLELRKVDEPKLGAIFVDLIGGAVGHRRKFGGGKGQAIAKAAGLNKGATPTVLDGTAGLGRDAFVLASLGCKVQMVERHPVVAALLDDGLARAKQDPEIGTWVSERMSLIHASSHDALDQLAQDREFVKPDVVYLDPMYPHPENKKKSALVKKEMRVFQSLVGADLDADGLLEPALALATKRVVVKRPDYANWLNEQKPSMAIETKKNRFDVYVKASMA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGCU_ECOLI
Sequence: MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKVTGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
What are the official names of this protein?
Uncharacterized FAD-linked oxidoreductase YgcU.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
Protein: FER1_CAUVC
Sequence: MTYIVTDACVRCKFMDCVEVCPVDCFYEGENFLVINPDECIDCGVCEPECPVDAIKPDTEDEADGKWLKINADYAKVWPNITVKGEPPADREDFERETGKFEKYFSEKPGKGS
What are the official names of this protein?
Ferredoxin-1, Ferredoxin I, FdI.
Protein: YMDA_ECOLI
Sequence: MFRPFLNSLMLGSLFFPFIAIAGSTVQGGVIHFYGQIVEPACDVSTQSSPVEMNCPQNGSIPGKTYSSKALMSGNVKNAQIASVKVQYLDKQKKLAVMNIEYN
What are the official names of this protein?
Uncharacterized protein YmdA.
What is the protein family that this protein belongs to?
To the N-terminal of the FimA/PapA family of fimbria proteins.
Protein: LIPL_CHICK
Sequence: MERGRGMGKTALLAVLCLCLRGAAGSDPEAEMNFEGIESKFSLRTPAEPDEDVCYLVPGQMDSLAQCNFNHTSKTFVVIHGWTVTGMYESWVPKLVDALYKREPDSNVIVVDWLVRAQQHYPVSAAYTKLVGKDVAMFIDWMEEKFNYPLNNVHLLGYSLGAHAAGIAGSLTKKKVNRITGLDPAGPTFEYADAPIRLSPDDADFVDVLHTYTRGSPDRSIGIQKPVGHIDIYPNGGGFQPGCNLGEALRLIAEKGFSDVDQLVKCSHERSIHLFIDSLLYEEKPSMAYRCNTKEAFEKGLCLSCRKNRCNNLGYKVNRVRTKRNTKMYLKTRAQMPYKVFHYQVKIHFFGKTNVTKVDQPFLISLYGTLDESENIPFTLPEVSSNKTFSFLIYTEVDIGDLLMLKLQWEKDTFFSWSDWWTPFAFTIQRVRVKSGETQKKVVFCSRDGSSRLGKGEEAAIFVKCLEQPVSRKRGGAKKASKENSAHESA
What is the function of this protein?
Key enzyme in triglyceride metabolism (By similarity).  Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (By similarity).  Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (By similarity).  Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity).  Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (By similarity).
What are the official names of this protein?
Lipoprotein lipase, LPL, Phospholipase A1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Secreted. Secreted, extracellular space, extracellular matrix. Note=Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells. Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non- coated endocytic vesicles.
Protein: TRPDH_NOSPU
Sequence: MLLFETVREMGHEQVLFCHSKNPEIKAIIAIHDTTLGPAMGATRILPYINEEAALKDALRLSRGMTYKAACANIPAGGGKAVIIANPENKTDDLLRAYGRFVDSLNGRFITGQDVNITPDDVRTISQETKYVVGVSEKSGGPAPITSLGVFLGIKAAVESRWQSKRLDGMKVAVQGLGNVGKNLCRHLHEHDVQLFVSDVDPIKAEEVKRLFGATVVEPTEIYSLDVDIFAPCALGGILNSHTIPFLQASIIAGAANNQLENEQLHSQMLAKKGILYSPDYVINAGGLINVYNEMIGYDEEKAFKQVHNIYDTLLAIFEIAKEQGVTTNDAARRLAEDRINNSKRSKSKAIAA
What is the function of this protein?
Catalyzes the reversible oxidative deamination of L-tryptophan to indole-3-pyruvate in the presence of NAD(+) (PubMed:24835098, PubMed:27815281).  Shows weak activity with L-phenylalanine, but cannot use other L-amino acids and D-Trp (PubMed:24835098, PubMed:27815281).  Cannot use NADP(+) for oxidative deamination of L-Trp, and shows only weak activity with NADPH for reductive amination of indole-3-pyruvate (PubMed:24835098).  Involved in the biosynthesis of scytonemin, a cyanobacterial radiation-absorbing pigment (Probable).
What are the official names of this protein?
L-tryptophan dehydrogenase, L-Trp dehydrogenase, TrpDH, NpTrpDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: PEPT_BACAA
Sequence: MKEELIERFTRYVKIDTQSNEDSHTVPTTPGQIEFGKLLVEELKEVGLTEVTMDDNGYVMATLPANTDKDVPVIGFLAHLDTATDFTGKNVKPQIHENFDGNAITLNEELNIVLTPEQFPELPSYKGHTIITTDGTTLLGADDKAGLTEIMVAMNYLIHNPQIKHGKIRVAFTPDEEIGRGPAHFDVEAFGASFAYMMDGGPLGGLEYESFNAAGAKLTFNGTNTHPGTAKNKMRNATKLAMEFNGHLPVEEAPEYTEGYEGFYHLLSLNGDVEQSKAYYIIRDFDRKNFEARKNTIENIVKQMQEKYGQDAVVLEMNDQYYNMLEKIEPVREIVDIAYEAMKSLNIEPNIHPIRGGTDGSQLSYMGLPTPNIFTGGENYHGKFEYVSVDVMEKAVQVIIEIARRFEEQA
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_MYCPN
Sequence: MKVKSAAKKRFKLTKSGQIKRKHAYTSHLAPHKTTKQKRHLRKQGTVSASDFKRIGNLI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: DOP2_XENLA
Sequence: MDVEEQELLGDYRYRNYSSVIEKALRNFESSSEWADLISSLGKLNKALQTNLKYCLLPRRIIISKRLAQCLHPALPSGVHLKALETYEIIFKIIGTKCLAKDLFLYSSGLFPLLSHAAMSVRPILLGLYETYFIPLQRALLPSLQAFITGLLPGLEEGSEIYERTDQLLQRLSVVVGQNVFYGSLWGSVLVSSSIRLPASLFVVSHINKDLSAQSQSYMLGKDQELAIKSLCASVVDSNVLVQRNTLEILLFFFPFNTCLVPDECSMLLHRSDMVRILAGSIQTVLRRDMSLNRRLFAWLLGSDIKGRHMAPELKDSSGDEEYCNHFFARYSKDLLVEALMQILHQNTLASDTEQGLLVYLKPFRILVSLLDKPEIGPPVVGELFLEVMRAFIAYCRDALGTQMQLSYSQNGAQLISAIKENKNASEIVKTVNLLISSLSSDFLWDYMTICFEDSFRRKDHDTPAGNYLGRAPSITEVCSLLVFLLDVIPLELYSEVQTQYLPQMLSFMAHSLSDNMDVLSLPELTLALKTCFKVLSKVQMPPAFLDMETPSSDTDPLKESENNPAPEVEGEMADDDPVFHPLKSEDSGIGLSASSPELSKHLRMPRVCPDKGDVWKKGGSMQMTLHCFQELVANFASKHLFRIQLKGEGQNSPENGVMTENDMNTKKRGSWQPKQITGPQFKQMLTDFFTPRAPMLKQRSEQSPNKTTNKETEEEWDIERLLQNTGEMKEDCREALAAACHVLLDCATFPVYMSEEETEHLYSVLSQVPGSSDVSFPLWFKTLMMVCCCVKDCYIQNVAISTLLEVINHSQSLSLVLADRMKRSKTPGFGEVFGKLQMVTIPPVSPGVLKLIADKTDFYPRVAHVLWNQLNIETREHHITCVELFYRLHCLAPSANICEEIICQTLLHNDKLTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLNCSDGAIGAAAQGWLVRALSLNDVARILEAVFLLLLHPKTQRNSIHCIKQKNSSEEFSYWCRKKRTSLKDLAAFRDSPLSSSEENLPQFNTVDRDALWAEVEKDPEKIKNELTEKRPADFRDAPYCVEQEQDYSEHTESADTSTGHNDSDNTSSFTPSSVDLSSDQNYRDNTAGQVTHKNTGQQNMDMPRQNTLLTLVRTESDVTQTSESLSSDDEADLELQAIRSSQLLKQQKEKEEMIEALFKHILLYLQPYDSKRVLYAFTVLEAILKTNPKEFIESVAATSMDTSSTAHLNLIYNLLARHQEALVGQSFYGKLQTQSPLMCPHSLLIELLTYLCLSFLRSYYPCYLKVSHKDVLGNRDVQVKSVEVLIRIMSQLVNIAKSAEGKKVEFIRFLLERCKVQEFVLLSLSASMYTSQKKYELMSAGGNRGIDLGFFEEGIINFGQDQIWSEHPLQIELLKLLQVLIVLEHHLRQLQDDQDTHGDLTKEWQRGINFQQSINAMQYVQAHSITSQGLFVSAVVKALRPDYGYGMHPQWVALVTSSLPFFGKSLGLTVAPFVVQICKNLDELVKQYENESFKISTTSKRENVSPDYPLTLLEGLTMIGHFCLLDHPTQSKKSSSSDPANLKNARNALLEELPRIINTMSLLWSIISKQEREKRPSDLLGTIKASSSVYFKSTKTLKQKILDFLNPLTSHLGVQLIAAVAAVWKKKRFNKSLSKAKILPVPSESQLIFVDLVCALKTLKTDTILHLVKEVVKKPPQIKGDEKSSLVDIPMLQFSYTFIQRLSGSELQENSQSLLALLKESVPLNLAPPGFFLLLSMLNDFVTRTPNLESKKDQKELQEVTQKILEAVGNVAGSSLEQTSWLSRNLEVKAQPQISLDDAEAEEEDLNDDSVVAQSSMVSASAPSMYSVQALSLLAEVLANLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNIPSFRAGAQLLSSLSGYAYTKRAWKKEVLDLYMDPGFFQMDTSCVHWKAIIDHFLTHEKTMFKDLMSMPSSSLKLYSSSEQKAMLLKRQGFAVLSGEVDQYHQYLPLIQERLTENIRMGQTPNMAAQMYLFFRVLLLRISPQHLTSLWPIMVTELIHTFVQLQEDLMDEVPTKSSKASKHKTATAEVNGTVYCEIQQSALELYLSACKFLDTALSIPPDKMPLFQLYRWAFVPEVDTEACSVPSEKVENYQECKPHVLRILELLRFRFGEKTTEDPKWKRTEFPLLNLHSICSVTQLTPFFRTLGYAFKAKGETTGESQGSEPTIEYPVEDFTKVLKELEENVESDFLEKLGS
What is the function of this protein?
May be involved in protein traffic between late Golgi and early endosomes.
What are the official names of this protein?
Protein dopey-2.
What is the protein family that this protein belongs to?
Belongs to the dopey family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: LEUD_MYCGI
Sequence: MEAFRTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRNDPSFVLNQPPFDQGSVLVTGPDFGTGSSREHAVWALMDFGFRVVISSRFADIFRGNAGKAGLLAAEVTQDDVELLWKVIEQHPGTEITVNLQDRSVTAGTVMVPFTIDDYTAWRLLEGLDDIGLTLRKLDEIEDFETHRPSWKPRTLPA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.