PharMolix/UniProtQA huggingface dataset:
Protein: QCR2_EUGGR
Sequence: MKSVVRSKGTQALFRRFSSALGDSINPNQVGVGDNVIRVNGRLFEVDKVQEKGLKTSVLDNGTKVITLDNGGSVAQLTFLYKDGPVYENIFNAGISSFMKHALTKDGLTSSEYITKTFLQKAGIIVHEPTVVNKSAIAFTVEGFRDTLAQPAVADKFWQSLLFPRFSPENVKEVKRLVELESKETKRDSPFAYLQDILHKTAFKGSPLGHTSFVPAYNLGYIDSNKLFDRWDAHYGFGNIAVIATNIEHEAVLAAITDSAWVARAHNKVGGVAAPASKYSGGEGYDVVHRAKEFDDQFTDVYSTYTAYAFKAPGRSNLKEHAASLVIAQALSNAVSPVLNTSFAPKRLEVFYQAYDTVGLIGLSSVQASNAQLKAFKAALSKIGTLSEADLAVHKSAALLTAYGNVESWRATQATLIDSFNTTGQPLSPLEIVSAIKAVSADTVKSVVATMLGSPATLVHHGDSPCAPTLDALQ
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: TM168_DANRE
Sequence: MSGQEKSDKSVDMWSFLRCLGYLSSFNLLVAVCLGMYVRWEQTSEPMILVLFILGLFVSAIACILYYYFSMESASLSLFHLWFGFLQGLLCFLNSPSLEDEIKEQVTNYLLLSSVSIRTLWALTERLCANPKYKPVVITSSELLELLGFGVASISLVFDKSLAMIALTFALTALIIDLRMKSPLALPNLACFSVIAAVTFFQSLKIQTNPFALSCYLGRLICEPLLDVYFSSLTATERWKQFLSAGRLWRRFSLFPLALVELLFFVVCAFKLGNLKDWYLVIPGFCIFGLLWILCHMVFLVTLWCFHTKLSECQKMWAAQRLQTLNLDRIMASRGMRHFCLISERLVLFCLMSTIILGAVSWQVANGLFMSVFLVVLPLESLAHGLFHELGNGLGGTCVGYAVVIPTCYSSADGQPVLLPPGQVQELHSTSTLNAVQRLFSHHLIQTFGCDYSTSLSLETLLVKLRSFLELCTAEGPRHDTYILYYSGHTLPSGDWTLAGGDYLRMKQILDMWREQNSSFSSRLILVLDTENSAPWVKAVRKVEGMYVAVQGAKLSPVQDAEGQDAPRLGDFTSEWVKYNCDPESGVQWSERGRVISAIYGVSKPWSDYALHLPTGSDVAKHWKTHFPKTTYPLVAVANWCCGLNLLWLCSVCLRCVRRLKLSWFPPSILDTGQGIKLVRS
What is the function of this protein?
Plays a key role in maintaining the cardiac electrical stability by modulating cell surface expression of SCN5A.
What are the official names of this protein?
Transmembrane protein 168-A.
What is the protein family that this protein belongs to?
Belongs to the TMEM168 family.
Protein: Y1059_MYCMM
Sequence: MTSTGSTRYDGDSWDLASSVGVTATMVAAARAMATRAENPLINDPYAEPLVRAVGVDLLTRLATGEFNVADLDDDPQRPLGPLGDVADNMAVRTRFFDDFFLDATRAGLEQVVILASGLDARAYRLPWPPQTVVYEIDLPQVIEFKSRTLADLGAAPTADRRVVAVDLREDWPAALRAAGFDPNQPTAWSAEGLLGYLPPEAQDRLLDTVTELSAPGSRLAAECLSSVDPGEEEQIKERMQEVSARWRAHGFDVDMVGLVYFGDRNEAVPYLSDRGWLLTSTPLPELRAANGLAPAAVDDDGPSVDMLYVSGTLYTTPRPDPAP
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MMAR_1059.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: EFG_STRP1
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAVAETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIAYLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIAGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3024_PSEE4
Sequence: MIISTTSQLEGRPVAEYLGVVSAESVQGINFVRDFFARFRDFFGGRSQTLESALKEAREQATEELKARARQLQADAVVGVDFEISMPSVQGGMVVVFATGTAVRLK
What are the official names of this protein?
UPF0145 protein PSEEN3024.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: ISPE_FUSNN
Sequence: MRISLNKYKIFSNAKINIGLNVFQKESDGYHNIDSIMAPIDLSDEMDVTFYSDLGDLKIECSDKSIPTDERNILYKTYKIFFEESKKEKEKIDIILKKNIPSEAGLGGGSSNAGFFLKLLNKHYGNVYNEKELEKLAMRVGSDVPFFIKNKTARVGGKGNRVDLVENNLKDSIILIKPLDFGVSTKEAYESFDNLKEVKYADFDKIIKNLKEGNRIALESNIENSLEQGILETDTNIKMLKMTLNSVVSGKKFFMSGSGSTYYTFVTELEKSQIETRLKTFVDNVKIIICKTIN
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PNP_STRPD
Sequence: MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGESTVLTAAVMSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFIINPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQEQIVAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVKAEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVVDFLPKVHGSGLFTRGQTQALSILTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGETGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITALQMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVDKIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKVGEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKIDEKGRVDASMKALIPRPPKPEKKEEKHD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNR_CHLPN
Sequence: MLKKPKRKPGRRTYGKSLKIFIPGTLFVHARKGFGFVSPDNPEEYPFDIFVPARDLRGALDGDHVIVSVLPYPRDGQKLKGTISEVLARGKTTLVGTITSLVSPTSALAYTSMSGSQSLIPVELLPGRTYKIGDRILLSTPPWVDKPQEGASPALQMLEFIGHITNAKADFQAIQAEYNLAEEFPPEVIEEASLFSQKHITQVLHSRKDLRDLLCFTIDSSTARDFDDAISLTYDHNNNYILGVHIADVSHYVTPHSHLDKEAAKRCNSTYFPGKVIPMLPSALSDNLCSLKPNVDRLAVSVFMTFTKSGHLSDYQIFRSVIRSKYRMTYDEVDNIIEKKHSHPLSKILNEMATLSKKFSDIREERGCIRFVLPSVTMSLDNLQEPVALIENHQTFSHKLIEEFMLKANEVVAYHISHQGVSLPFRSHEPPNDENLLAFQELAKNMGFDITFTPTQEPDYQYLLQTTSAGHPLEQVLHSQFVRSMKTASYSTENKGHYGLKLDYYTHFTSPIRRYIDLIVHRLLFNPLSIDQTHLEIIVRACSTKERVSAKAENSFENLKKTRFINKFLQEQPKTTYHAYIITANHEGLSFVVTEFCHEGFIAAAELPKEYSLKKNALPESIPDKMKPGASIKVTIDSVNLLTQKIVWSIATTTEDKPKKIKKTPSKKKGTKKRAS
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
What are the official names of this protein?
Ribonuclease R, RNase R, VacB protein homolog.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_KOSOT
Sequence: MLMPKRVKYRKQQRGKMRGKAKGGTLVHFGDWGLKALEPHWITAQQIEACRIAIMRTLKRNGKVWIRVFPDKPITSKGIGVRMGKGKGDVEGWVAVVKPGKILFEIGGINDELAKEALAYAATKLPIKTKIVPRYEIGGEL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CYSZ_CITK8
Sequence: MVSSSATAPRSGFYYFSQGWKLVTQPGIRRFVILPLLVNILLMGGAFWWLFTQLDVWIPSLMSHVPDWLQWLSYLLWPIAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGVLGIMKDVPRIMKREWQKFIWYLPRAIVLLILYFIPGVGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTQKVANMQFGALTSLFTMIPVLNLVIMPVAVCGATAMWVDCYRSKHALWK
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLA_FRAT1
Sequence: MKKIIICFIFVFSINVSFADATSELIDKIKNIHSMTANFNQKLIDGQTNNNLNSKGNMSLKKPQYFKWITTSPNNQEIVSNGTKLWIYDGDLDQLIIKKVSNDIAQFPYLILLSKNTNNINKLFTVTAQDNNSYILKPKNDQMIDSIKIKFTPNNQLEYLEISTSLNQFTKIEFNNVKTDVDISNTSFDFKAPQNTDIIDETKFA
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KCNT1_CHICK
Sequence: MARAKLKNSPSESNSHVKTVPPATTEDVRGVSPLLPARRMGSLGSDVGQRPHAEDFSMDSSFSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPEEGIGCWECEKQNYTLFNQSTKINWSHIFWVDRKLPLWAVQVSIALISFLETMLLIYLSYKGNIWEQIFRISFILEMINTVPFIITIFWPPLRNLFIPVFLNCWLAKYALENMINDLHRAIQRTQSAMFNQVLILICTLLCLVFTGTCGIQHLERAGEKLSLFKSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDIQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCVCPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFMEYEGKSFTYAAFHAHKKYGVCLIGIRREENKSILLNPGPRHIMAASDTCFYINITKEENSAFIFKQAEKQKKKGFAGRGTYDGPSRLPVHSIIASMGTVAMDLQNTECRPTNSSKLALPAENGSGNRRPSIAPVLELADTSSLLPCDLLSDQSEDEMTQSDEEGSAVVEYVKGYPPNSPYIGSSPTLCHLLPEKAPFCCLRLDKGCKHNSFEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPEHHFLEAICCFPMVYYMEGTIDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSIITELTHPSNMRFMQFRAKDSYSLALSKLEKKERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHMFATSEPHDIRAQSQISINVEDCEDTKDVKEHWGIKTGHHRNSCSSDQSEHPLLRRKSMQWARRLSRKGNKHSGKTAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYDEMNDHQNTLSYVLINPPPDTRLELNDIVYLIRSDPLAHVANDGHSRKSSCSNKLGPCNPETRDETQL
What is the function of this protein?
Generates outwardly rectifying currents that are suppressed by elevation of intracellular calcium.
What are the official names of this protein?
Potassium channel subfamily T member 1, Sequence like a calcium-activated potassium channel subunit.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS19_METSB
Sequence: MARSIWKGPFVDGYLLKKADASRATGRSEVIKIWSRRSTILPQFVGLTFGVYNGHKHVPVNVTEEMIGHKFGEFSPTRTFHGHSADKKARRG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: LGTE_NEIMB
Sequence: MQNHVISLASAAERRAHIAATFGVRGIPFQFFDALMPSEELNRMMAELVPGLAKQHLLSEVEKACFMSHAVLWKQALDEGLPYVAVFEDDVLLGKDAEKFLAEDTWLEERFDKDSAFIVRLETMFAKVIVRPDKVLNYENRSFPLLESEHWGTAGYIISREAMRFFLERFAVLPAEWIKAVDWMMFTYFFDKEGMPVYQVNPALCTQELHYAKFLSKNSMLGSDLEKDREQERRHRRSLKVMFDLKRALGKFGREKKKRMERQRQAELEKAYGRRVISFK
What is the function of this protein?
Adds the first galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS).
What are the official names of this protein?
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtE.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 25 family.
Protein: RELE_ECOLI
Sequence: MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKRIL
What is the function of this protein?
Cross-talk can occur between different TA systems.  Ectopic expression of this toxin induces transcription of 7 tested TA systems (dinJ/yafQ, hicAB, mazEF, mqsRA, prlF(sohA)/yhaV, relBEF and yefM/yoeB) with specific cleavage of the relBEF mRNA produced immediately upstream and within the relB coding sequence.  The cleaved mRNA can be translated into RelE, leading to a positive feedback cycle of RelE expression.  The relBEF operon is required for transcription of the mazEF TA system operon during amino acid starvation.
What are the official names of this protein?
mRNA interferase toxin RelE, Endoribonuclease RelE, Toxin RelE.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family.
Protein: FCN1_HUMAN
Sequence: MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
What is the function of this protein?
Extracellular lectin functioning as a pattern-recognition receptor in innate immunity.  Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system.  May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097).  Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
What are the official names of this protein?
Ficolin-1, Collagen/fibrinogen domain-containing protein 1, Ficolin-A, Ficolin-alpha, M-ficolin.
What is the protein family that this protein belongs to?
Belongs to the ficolin lectin family.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Peripheral membrane protein; Extracellular side. Note=Found on the monocyte and granulocyte surface (PubMed:20400674).
Protein: TSAD_HYPNA
Sequence: MRAMSKSLTILGIETSCDETAAAVLRYEDGRATLLSDVIRTQLAEHAPYLGVVPEIAARAHAELADLTVAAAMNASGLSYAELDGVAATAGPGLIGGVLVGLMTGKAIAQAAGKPFIPVNHLEGHALSPRLSEDCPFPYLLLLVSGGHCQFLDVRGLGDYRRLGSTIDDAVGEAFDKVAKLLGLGFPGGPAVEALARNGDPKAHDFPRPLLNRPGLDMSFAGLKTAVARASANAKSEAEKADICASFQAAICDVLAEKARRALEGFDAGAGDKRFVVAGGVASNKAIRAALETAATAQGARLIAPPLRHCTDNAAMIALAGAEHLAAGLCETDGLASSARPRWPLDEASAKADPVFGAGRRGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_LEPIC
Sequence: METRKIIHVDMDAFYASVEQRDFPEYKGKPLIVGGPPNSRSVVSAASYEARKFGVRSAMPCSKAAQLAPQAIFVFPRFEVYKEVSKQIREIFLEYTDLVEMLSLDEGYLDVTFNKKNIPFAVTIAKEIRTEIFKRTELTASAGVGNSKFISKLASEKNKPNGLTVVLPDDVISFIDPLPVSSFHGVGKVTARKMKELGIYTGKDLRTKSIDELVQHFGKMGIYYYKISRGEDERMVQSSRERKSLGAESTFDRDKLDYDDLLKQLKDVAVVVERRLEKKDFAGKTLTLKIKFYDFSLKTRSKTLSEPIFKADELYSTAIELFEEFFEIKYGKKSAIKAIRLLGISLSHPNSENEDPNLFLNL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_PECAS
Sequence: MSYSGEQERQAPHMALVPMVVEQTARGERSYDIYSRLLKERIIFLTGQVEDYMANLVVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQACSMGAFLLTAGAKGKRICLPNSRVMIHQPLGGFQGQATDIEIHAKEILKVKAKMNELMAKHTGQPLEAIERDTERDRFLSASEAVEYGLVDSVFTNRG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_HYDCU
Sequence: MADTIKHTPMMQQYLAVKADYPNQLLFYRMGDFYELFYEDAVKASELLEITLTARGKSGGNPIPMAGIPHHSAEGYLAKLVKLGQSVAICEQIGDPSISKGPVERKVVRVITPGTLVEDALLEDKSENLLAAIFQQADEYGLATLDVASGRFEATLLPDSTQLSAEVERLKPAEIILPDDPLFKQNLPESIQNRPGLVDYPSWHFEKDSCRKRLIDHFGTQDLVAFGCDQLPAVISAAGVILHYAQSMLQNTLAHVFSLQTYQADDALALDAMSRRNLELDTNLTGGKNHTLFAILDNATTAMGSRLMNRWLNQPLRNRDIINDRFNAIEDIIEQHSQEEFRSALKPIGDLERILSRVSLYSARPRDILHLGRSLNQLPELQALLKQQTANKWQQLSKQLGLYPELASQLETALVESPPMLMRDGGVFAEGYDSELDELRNLKNQAGDYLLALEAREKERTGITTLKVGYNRVHGYYIEVSKLQSDNVPADYVRRQTLKAQERYITPELKEFEDKVLSANEKALAREKWLYQQLLERLNQDLQALQRTAAALAETDVLVSLARQAINLNLTRPTLSSEPGIDIKQGRHLTVEALSNQPFIPNDTCFDEQRRLQIITGPNMGGKSTFMRQTALIAIMAYMGSFVPAESATLGPIDRIFTRIGASDDLTSGRSTFMVEMTETANILHHASPESLILMDEVGRGTSTFDGLALAWAIAEQMAQSIQGYCLFATHYFELTTLVEQFNNTVNIHLSAIEHQDKIVFMHQVEEGPASQSYGLQVAALAGVPTAVIDKAKKHLHRLENQTAAQQQTSGTASSAKESVQQFDLFAQPALPEAIETMLTDLKALSVDDLTPRQALEKLYEVTNTVKNASE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DTD_THESQ
Sequence: MRAVVQRVSEARVVVEEETVGAIGKGLLVFVGVGKDDTEEDCEWLADKVSGLRIFEDEDGKMNLSVKDINGEVLVVSQFTLYGDCRRGKRPSFTEAAPPDKGKALYEKFVELLREKGLKVETGKFRAHMHVHLVNDGPVTILLDSSKLF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAP_CERV
Sequence: MNLATIASEIEVVKTNQKTIESKIDQILAKIGSTPDESSNLESVAAKIISDLTKEMKECHCNKEIVEILNKDKAIIPSPEQDSIQKRLSEPQYTFPNFDVGNEGMGSSTNPNALKWPPTEKPQPWPPR
What is the function of this protein?
Plays a role in virus cell-to-cell and plant-to-plant transmission.  Interacts with virion icosahedral capsid and movement protein, thereby facilitating virion cell-to-cell transmission through plasmodesmata opened by viral movement protein.  Also interacts with aphid transmission factor, attaching the virion to aphid stylet when the animal feeds on an virus infected plant.  Aphid saliva may later detach the virion, inducing release of infectious particles when the animal feeds on a new plant (By similarity).
What are the official names of this protein?
Virion-associated protein, Vap, Protein 3, P3.
What is the protein family that this protein belongs to?
Belongs to the caulimovirus ORF III family.
What are the subcellular locations of this protein?
Virion. Host cell junction, host plasmodesma.
Protein: Y5A4_ENCCU
Sequence: MKSLPLLGILAFAANRLSAKHISHHYDVHIMGNYVDSLKKANPPSESNEMISKARYLNKVYFDICEPAYRDAGAIMTQERFKYIALVLNFLYEFCSAREYELAAVTATVLHNTSYLRIFEAPGSDKYKPRGIFQICTKKNYAILESIAFFYHDYVENPERVGTFSIHVLVDITCFWLHMSFAKKRRIDIYDVLSICNPSEYEILRNKSKYSREEVKKAEERFANRDEIYQKMLSIIYINYYRE
What are the official names of this protein?
Uncharacterized protein ECU05_1040.
Protein: COBS_MYCSK
Sequence: MIGSLAGAFAFGTVLPVPAGSTATLGRGVMTALPGVGIVLGAVAAAVLWAGSWAFGPHSALAGLLAVAVLLLATRGMHIDGLSDTVDGLGCYGAPERALRVMRDGSAGAFGAASIVVAVGAQTLAFSMLPGGWSGAVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVVLVWLAAVAALAIPATERIWQGPLTVVVAVGMTALLVRHCVRRFGGITGDVLGAAIEVTTTVVAVGLVIR
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y275_METSB
Sequence: MRDMLGLMKQAQAMQEKIQQMQAEIERLEVEGQSGGGMVRVTLSAKGQLRNLAIDDQLIKADEKQILEDLIITAHEDARKKAERLMEEKMQGVTAGLALPPGMKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Msil_0275.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CARA_THISH
Sequence: MNFTPALLALEDGSLFHGISIGAPGQTVGEVVFNTAMTGYQEILTDPSYARQIVTLTYPHIGNTGVNPEDEESAGVHAAGLVIRDLPPLVSSWRSRESLPDYLTRFGVVAIANIDTRRLTRILREKGAQNGCIMAGEIDEQAALAAARGFPGLKGMDLAKEVSTAEIYDWTEGTWQLGSGHAPAPASSPYKVVAYDFGVKRNILRMLVDRGCQVTVVPAQTPAAQVLAMQPDGVFLSNGPGDPEPCDYAISAIREIVDTGIPTYGICLGHQLLGLASGARTVKMKFGHHGANHPVQDLDSKRVMISSQNHGFAVDENTLPGNVKATHRSLFDGTLQGIARTDRPAFSFQGHPEASPGPHDVAPLFDRFIELMKPQGVRK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.