PharMolix/UniProtQA huggingface dataset:
Protein: PRR30_MACFA
Sequence: MLPQNKDQVLPQTSVLPGCPPWGFSQLVDSSPHNLQPLSAHQSLRPSHPPFFSTQSHHPSFSPPASPSPGFQFGSCDPNSDFVPHPCSPSLPSSPTFFHQNYLSLPNPRASSPSNHWLYPSPPLTPSFSPSQPQNSSLPHSPCQSPSHPEDLHSSTLTSPGPSPPSQRLHSNRQTWRWHQYRDTGSGSPGVVERCVPSEKDPAQFRDPGALAQALVVQLGHRRIAHDLRLLLLQHLWLGRTGQAPVVEYPICLVCLRPRSPSCPLPKYRTGPRLLAFPQLLPCVEGQESGPLRIGIGFGLRLPQGQARALHLLPEKRPKEVGPQGKDPQACGHPSPAFQPPAAQARADPAPGTPSQTRSFRSAGLQSPNSPRCFSGPPPRAPKQATTSPKPRPCPAPKRPVSLELILQKSSV
What are the official names of this protein?
Proline-rich protein 30.
Protein: SEC11_MAGO7
Sequence: MLSSLGNPRQAATQLLNFALILSTAFMMWKGLSVATDSPSPIVVVLSGSMEPAFQRGDLLFLWNRNIVQETDVGEIVVYNVKGKDIPIVHRIVRKFGAGPKAKLLTKGDNNAADDTELYAKDQDYLERKDIIGSVVAYIPFVGYVTIMLSEHPWMKTAMLGIMGLMVVLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: CUTC_ECOLI
Sequence: MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLKSVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVDMPRMEKIMAAAGPLAVTFHRAFDMCANPLYTLNNLAELGIARVLTSGQKSDALQGLSKIMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSSDEHADEYSRYIVDGAAVAEMKGIIERHQAK
What are the official names of this protein?
PF03932 family protein CutC, Putative copper homeostasis protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIS_ECHOC
Sequence: MIPVLLVTICLAVFPFQGSSIILESGNINDYEIVYPKKVAVLPTGAMNSAHPCYDPVTCQPKEKEDCESGPCCDNCKFLKEGTICKMARGDNMHDYCNGKTCDCPRNPYKGEHDPMEWPAPAKGSVLM
What is the function of this protein?
The short monomeric disintegrin ocellatusin inhibits ADP-induced platelet aggregation (IC(50)=168 nM).  Inhibits alpha-5/beta-1 (ITGA5/ITGB1) integrin and induces the expression of a ligand-induced binding site epitope on beta-1 integrin subunit.  Has a direct chemotactic stimulus on human neutrophils in vitro.
What are the official names of this protein?
Disintegrin ocellatusin, Short ocellatusion precursor Eo10c-10.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Short disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RRG9_EMENI
Sequence: MPSICPKSAMISLPTVLQSIFAFEVAPQIRNSSVRSLNRSSLRHRLRSTRTITTVSIDSIPVPSAQKPDDRVTSPSEPSLTADKSTASDTSSSNPASKATSADNSGSARRTKTNTKTSNEKQASDHENKKNIKKSAKETTASNAPKPPKEKEPWQIQKEALKRKFPTGWAPPKKLSPDAMEGIRHLHHIAPDQFTTPVLAEEFKVSPEAIRRILKSKWRPSGEELEERRKRWEKRHDRIWSHLSELGLRPKVPDYGSDADAVLYKRKSKGV
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SPICE_PONAB
Sequence: MSFVRVNRCGPRVGVRKTPKVKKKKTSVKQEWDNTVTDLTVHRATPEDLVRRHEIHKSKNRALVHWELQEKALKRKWRKQKPETLNLEKRRLSIMKEILSDQYQMQDVLEKSDHLIAAAKELFPRRRTGFPNITVAPDSSQGPIVVNQDPITQSIFNESVIEPQALNDVDGEEEGTVTSQSGESENENELDNSLNSQSNTNTDRFLQQLTEENSELISKLWTDIQQKIVTQSQITPPGTPSSALSSGEQRAALNATNAVNRFQTRLQPEESTETLDSSYVVGHVLNSRKQKQLLNKVKRKPNLHALSKPKKNMLSGSTTSADLPNRTNSNLDVLKHMIHEVEHEMEEYERWTGREVKGLQSSQGLTGFTLSLVSSLCRLVRYLKESEIQLRKEVETRQQLEQVLGDHRELIDALTAEILRLREENAATQARLRQYMVTTDEQLISLTHAIKNCPVINNRQEIQASESGATGTRVMDSPEGPVVNANVSVPLMFREEVAEFPQEQLPVKLSQVPDPPDKMNLAKNFPAHIFEPAVLLTPPRQKSNLKFSPLQDVLRRTVQTRPAPRLLPTVEIIEKEQNWEEKTLPIDTDSQNSSEENRLFTQRWRVSHMGEDLENKTQAPFVNLSQPLCSSHSNTQQSRSPTFSEELPVLGDGQQLRTNESLIQRKDIMTRIADLTLQNSAIKAHMNNIIDPRGEQGDGLRELNKQESASDMTSTFPVAQSLTPGSMEERIAELNRQSMEARGKLLQLIEQQKLVGLNLSPPMSPVQLPLRAWTEGAKRTIEVSIPGAEAPESSKCSTVSPVSEINTRRSSGATSNSCSPLNATSGSGRFTPLNPRAKIEKQNEEGWFALSTHVS
What is the function of this protein?
Regulator required for centriole duplication, for proper bipolar spindle formation and chromosome congression in mitosis.
What are the official names of this protein?
Spindle and centriole-associated protein 1, Coiled-coil domain-containing protein 52.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle.
Protein: GLPK_SINFN
Sequence: MGGYILAIDQGTTSTRAIVFDGKQQVAGVGQKEFKQYFPKSGWVEHDPEEIWETVLFTARQAIEKAGISATDIAAIGITNQRETVVVWDRATGKPIHNAIVWQDRRTASFCDKLKKQGLEKTFSKKTGLLLDPYFSGTKLNWLLTNVKGAPARAAKGELCFGTVDTFLIWRLTGGKSFVTDATNASRTLIYNIVDNSWDDELTDILRIPRVMLPEVKDCAADFGVTDASLFGAAIPILGVAGDQQAATIGQACFKPGMLKSTYGTGCFALLNTGKDIVRSKNRLLTTIAYRLNGETTYALEGSIFVAGAAVQWLRDGLKVIKAAPDTGTLAESADPTQDVYLVPAFTGLGAPHWDPDARGAIYGMTRNTGPAEFARAALESVCYQTRDLLDAMHRDWRSNGKDTVLRVDGGMVASDWTMQRLSDLLDAPVDRPVILETTALGVAWLAGSRAGVWPKQEEFAKSWARDRRFEPKMDGTTRKGKLKGWRSAVKRTLMAA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: MUTS_BURP0
Sequence: MATQIDASSEAAAATAAAQHTPMMQQYLRIKSEHPDTLVFYRMGDFYELFFEDAEKAARLLDLTLTQRGASAGTPIKMAGVPHHAVEQYLAKLVKFGESAAICEQIGDPATSKGPVERKVVRVVTPGTLTDAALLSDKSDVFLLALCVGHNKRGVASNIGLAWLNLASGALRLAELAPDQLGAALERIRPAEILAADGTIESVPAGMGAITRVPAWHFDIASGTQRLCDQLEVASLDGFGAQALTSANGAAGALLIYAAATQGQQLRHVRSLKVENESEYIGLDPSTRRNLELTETLRGTESPTLYSLLDTCCTAMGSRLLRHWLHHPPRASVAAQARHQAIGALLDAPPNAGLDSLRSALRQIADVERITGRLALLSARPRDLSSLRDTFAALPALRERVAEIASNAAALGRLEAALEPPPGCLDLLTRAIAAEPAAMVRDGGVIARGYDAELDELRDISENCGQFLIDLETRERARTGISNLRVEYNKVHGFYIEVTRGQTDKVPDDYRRRQTLKNAERYITPELKTFEDKALSAQERALARERALYDGVLQALLPHIEGCQRVASGLAELDLLAAFAERARTLDWVAPEFTDEIGIEIDQGRHPVVEAQVEQFIANDCALNPERKLLLITGPNMGGKSTFMRQTALIALMAYVGSYVPAKAARFGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILNDATPHSLVLMDEIGRGTSTFDGLALAWAIARHLLSHNRCYTLFATHYFELTQLPAEFPQAANVHLSAVEHGHGIVFLHAVEEGPANQSYGLQVAQLAGVPAPVIRAARKHLEHLEQQSAAQATPQLDLFAAPPVVDEPECNEPPAAATPHPALERLLELDPDDLKPRDALDLLYELHTLARSGPADAQR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DER_CHLP8
Sequence: MKPLIALVGRPNVGKSTLFNRILRQKSAIVDPTPGVTRDRHINPGEWQGKQFLLMDTGGYAPENDSLSVAMLDQTMRAIADADAIIFMVDARSGLTYLDLDIAKILKQTFSDKKIFFAINKVDNPQLALEAAAMVRSGFTEPYLISARDGGGVADMLDDILETLPCPESEDEELDDDSIKLAVLGRPNVGKSSLVNALLGTDRQIVSDVPGTTRDAIDSVLKRNGKEYILIDTAGLRKRTKIDPGIEYYSSLRTERAIERCQVALVLLDAQLGLESQDMKIIHMAIERKKGVLILVNKWDLVEKDSKTSKKFTDNLMMQLGNIGYIPIIFTSALTKKNCYRAIDTAAQIAINRRQKISTSNLNRFLQEALAMRHPASKSGKELKIKYMTQIEAGHPVFAFFCNDPQLLENNFKRFLEKRLRESFDFEGLPITMRFLRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PIMT_IGNH4
Sequence: MEEKKRELIRNLIAEGYIKRKEVAEAMMKVPRELFVPEELRHMAYEDTPLPIGAGQTISAPHMVAYMVEAAELRRGDKVLEVGTGSGYHAAVMAELVGPEGHVYTIERIPELAERARERLKALGYNNVTVLVGDGSKGYPPAAPYDKIIVTAAAKRVPEALLKQLKVGGIMVIPVEEEPGYQVLYKIIKTPEGYVIKKLLPVAFVPLIEEE
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_THENN
Sequence: MRHRMKRHKLGRYGSHRRSLLRNLSREIVEHGSIVTTTAKAKALKTFMDKLVSKAIEAATTEDRARSVHLRRQINAVLGDRRLTNKLVDEIAKNYVGRRGGYVRVLRIGFRRGDAAEMSLVQLVEASSQEG
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SIRS_LEPMC
Sequence: MSPSKTTPPSPTALVYGATGVTGWGLCKNLLEQQADSASTPTFSRVIGVCKQPAQDLGLFLEDKRFELVDGVDLLQGEDSVVEVLKEVKGIENVTHVFYVANRNSPSDGPDERISFNVKMIQSAVKAAEQLSSNMQVLIMQTSINVYGIFASLMGGTLTCPSPLVESADRTPSPYREMDVHYAQCDELKRLSKGKSWSWFEVRPDAVIGYVPRRHENNFTVSLGLFLATYAHVHGAGAPVRFPGTPESWKCKFSMVSQDQLARFEIHLATHAEGLQSGEAFNVSNGDVLTWSKLWPEAAARFGLRGVGPEGAGEEEGKGEAEGGAKGATGWSWPLGDETTMKKWEEENQVQKGWGGNLSEVCFVNTMRPTVDRILSLDKAKKIGFEARDDTIAAFDKAWALFKKARILP
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of sirodesmin PL, an epipolythiodioxopiperazine (ETP) characterized by a disulfide bridged cyclic dipeptide and that acts as a phytotoxin which is involved in the blackleg didease of canola (PubMed:15387811, PubMed:18272357, PubMed:19762440).  SirD catalyzes the O-prenylation of L-tyrosine (L-Tyr) in the presence of dimethylallyl diphosphate (DMAPP) to yield 4-O-dimethylallyl-L-Tyr, and therefore represents probably the first pathway-specific enzyme in the biosynthesis of sirodesmin PL (PubMed:19762440, PubMed:21038099, PubMed:24083562).  4-O-dimethylallyl-L-Tyr, then undergoes condensation with L-Ser in a reaction catalyzed by the non-ribosomal peptide synthase sirP to form the diketopiperazine (DKP) backbone (PubMed:18272357).  Further bishydroxylation of the DKP performed by the cytochrome P450 monooxygenase sirC leads to the production of the intermediate phomamide (PubMed:27390873).  This step is essential to form the reactive thiol group required for toxicity of sirodesmin PL (PubMed:27390873).  The next steps of sirodesmin biosynthesis are not well understood yet, but some predictions could be made from intermediate compounds identification (PubMed:18272357).  Phomamide is converted into phomalizarine via oxidation, probably by sirT (PubMed:18272357).  Further oxidation, methylation (by sirM or sirN) and reduction steps convert phomalizarine to deacetyl sirodesmin (PubMed:18272357).  Finally, acetyltransferase sirH probably acetylates deacetyl sirodesmin to produce sirodesmin PL (PubMed:18272357).
What are the official names of this protein?
Short chain dehydrogenase sirS, Sirodesmin biosynthesis protein S.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. Highly divergent.
Protein: HCHA_ECOLC
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR12_EMIHU
Sequence: MPTIQQLVRFERQTSEKKTKSPALKSCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNIQEHSVVLIRGGRVKDLPGCRYHVVRGSLDASGVKDRKQGRSKYGGKRPKGD
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EF1A_METMJ
Sequence: MAAEKPHMNLAVIGHIDHGKSTTVGRLLFETGTVPPHIIESFRKEAESKGKGSFEFAWVMDSLKEERERGITIDIAHKRFDTDKYYFTVVDCPGHRDFVKNMITGASQADAALLVVAAPDGVMEQTKEHVFLSRTLGINQLIIGINKMDAAKYDEKRYNEVKEQLSQLLKMVGYKPDDISFIPMSAFVGDNIAKKSENTPWYKGPTVLDALNALSEPEKPTNLPMRLPIQDVYSISGIGTVPVGRVETGIMKKGMKVSFMPANKEGEIKSIEMHHEEIPQALPGDNVGFNVRGIGKGDIRRGDVCGPSDVPPTVAEEFIAQVVVLHHPSALTVGYTPVFHCHTAQIACSFVELMKKLDPRTGQVKEENPTFLKTGDAAIVKIRPTQPMVIEKVKEIPQLGRFAVRDMGSTIAAGVCMDITPKQMR
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_BURP1
Sequence: MGKIIGIDLGTTNSCVAIMEGNQVKVIENSEGARTTPSIIAYMDDNEVLVGAPAKRQSVTNPKNTLFAVKRLIGRRFEEKEVQKDIGLMPYAIIKADNGDAWVEAHGEKLAPPQVSAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAFGLDKAEKGDRKIAVYDLGGGTFDVSIIEIADVDGEMQFEVLSTNGDTFLGGEDFDQRIIDYIIGEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSSQQTEINLPYITADASGPKHLNLKVTRAKLEALVEDLVERTIEPCRTAIKDAGVKVSDIDDVILVGGQTRMPKVQEKVKEFFGKEPRRDVNPDEAVAVGAAIQGQVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMINKNTTIPTKHAQVYSTADDNQGAVTIKVFQGEREMAAGNKLLGEFNLEGIPPAPRGVPQIEVTFDIDANGILHVGAKDKATGKENKITIKANSGLSEAEIEKMVKDAEANAAEDHKLRELAESRNQGDALVHSTKKALTEYGDKLEAGEKEKIEAALKELEDVLKNASSDKAAIDAKVEAVATASQKLGEKMYADMQAQQAGAAGAAGAAAEGASAQGGAQPPDDVVDADFKEVKKD
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RF1_PARP8
Sequence: MKTSMQAKLDQLTTRLAELNDLLSREDITSNIDQYRKLTREHAELQPVVEQYGLWRQTMNDAATAQELLSDASMKDFAEEEIRASRERMETLESELQKMLLPKDPNDDRNIFLEIRAGTGGDESALFAGDLLRMYLRYAERNRWQVEMMSASESDLGGYKEVIVRIAGEAAYSKLKFESGGHRVQRVPATETQGRIHTSACTVAVMPEADEIGEVEINPADLRIDTFRASGAGGQHINKTDSAVRVTHLPTGIVVECQDDRSQHKNKDRALKVLAARIKDKQYHEQHAKEAATRKSLIGSGDRSERIRTYNFPQGRLTDHRINLTLYRLESIMEGDLDELIAALVSEHQAELLASLGDAD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAG_SHISS
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_STAA9
Sequence: MKKKALLPLFLGIMVFLAGCDYSKPEKRSGFFYNTFVDPMKNVLDWLGNNLLNDNYGLAIIILVLVIRIILLPFMLSNYKNSHMMRQKMKVAKPEVEKIQEKVKRARTQEEKMAANQELMQVYKKYDMNPIKSMLGCLPMLIQLPIIMGLYFVLKDQLVDGLFKYPHFLWFDLGRPDIWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMIIWISLSSASALGLYWSVSAAFLVVQTHFANIYYEKVAKKEVQPFIEAYEREHNGGSNKKGKNTQVVSKKKKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS10_METFK
Sequence: MAAQKIRIRLKAFDYRLIDQSALEIVETAKRTGAVVKGPVPLPTRIERFDILRSPHVNKTSRDQFEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RS8_DICTD
Sequence: MTVTDPIADMLVRIKNANMRRHPTVDVPYSKMKEKIIEILLREGYIAKYEVIGEIPQKYIRVYLKYKGKTPVIQDVKRVSKPGRRYYVNKEEIPRVLGGLGIAILSTSKGIMTDKEARLLGIGGELICMVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ERA_ECOBW
Sequence: MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: LRG1_YEAST
Sequence: MIQNSAGYRSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYFRRHNLLCHVCDTPLRGLYYTAFGYRYDEEHFSCTICATPCGVKKCFMYGNQLYCKYHFLKYFSKRCKGCEFPISDQYIEFPKGEEIHCWHPECYGIHKYWHVNLAAETVGLQYLPKLEYNPNSGDKDINPTAYELDKQMQAFNFILSKTWSVLYRFEEEAASCISDMFQYLTSNDQLKGIESTGLLVLKIDCLFRGLDTLNLSTNKSMPVNSDQECIENNAMAASKYSKFPKNLSTKIMIYLQLLRKLGTENKNETITISSFMSVITGLAHFLKLLTRFGLYTALENNKLTHSVNPLLRFLREVEKNELFENNPFQYIKTPVNATDSCAGCNKYIQEECIQFYEHRWHIACFTCSSCHKNINPRSLTDPTFNKEKKKILCSHCSIDDPASVPGFKFVTKLAQLIFLLKIALVKSRTVMLKSKASNKVGRNSLQSTMLKEQTYIRTLNDIKRLRSRRESVRVTHNKQQARKSVILETAETDLNDPTKQGDSKNLVIQTDDPSSSQQVSTRENVFSNTKTLTLDDISRIVAAEQARELRPNAFAHFKKLKETDDETSNVVPKKSGVYYSELSTMELSMIRAISLSLLAGKQLISKTDPNYTSLVSMVFSNEKQVTGSFWNRMKIMMSMEPKKPITKTVFGAPLDVLCEKWGVDSDLGVGPVKIRIPIIIDELISSLRQMDMSVEGIFRKNGNIRRLRELTANIDSNPTEAPDFSKENAIQLSALLKKFIRELPQPILSTDLYELWIKAAKIDLEDEKQRVILLIYSLLPTYNRNLLEALLSFLHWTSSFSYIENEMGSKMDIHNLSTVITPNILYLRHKEISNDNVPDEPESGLVDSFAQNKGENYFLAIEIVDYLITHNEEMAMVPKFLMNLLKDVQLQKLDNYESINHFISTVMQSKTIDYSECDIKTPVTVKDSTTTVIQGEINK
What is the function of this protein?
Acts in signal transduction.  Activates CDC42, RHO1 and RHO2.  Negatively regulates 1,3-beta-glucan synthesis.  May be responsible for the down-regulation of CDC42 during mating.
What are the official names of this protein?
Rho-GTPase-activating protein LRG1, LIM-RhoGAP protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Bud. Bud neck. Note=Localized to the bud site during bud formation and at the bud neck during cytokinesis.
Protein: ARE1_YEAST
Sequence: MTETKDLLQDEEFLKIRRLNSAEANKRHSVTYDNVILPQESMEVSPRSSTTSLVEPVESTEGVESTEAERVAGKQEQEEEYPVDAHMQKYLSHLKSKSRSRFHRKDASKYVSFFGDVSFDPRPTLLDSAINVPFQTTFKGPVLEKQLKNLQLTKTKTKATVKTTVKTTEKTDKADAPPGEKLESNFSGIYVFAWMFLGWIAIRCCTDYYASYGSAWNKLEIVQYMTTDLFTIAMLDLAMFLCTFFVVFVHWLVKKRIINWKWTGFVAVSIFELAFIPVTFPIYVYYFDFNWVTRIFLFLHSVVFVMKSHSFAFYNGYLWDIKQELEYSSKQLQKYKESLSPETREILQKSCDFCLFELNYQTKDNDFPNNISCSNFFMFCLFPVLVYQINYPRTSRIRWRYVLEKVCAIIGTIFLMMVTAQFFMHPVAMRCIQFHNTPTFGGWIPATQEWFHLLFDMIPGFTVLYMLTFYMIWDALLNCVAELTRFADRYFYGDWWNCVSFEEFSRIWNVPVHKFLLRHVYHSSMGALHLSKSQATLFTFFLSAVFHEMAMFAIFRRVRGYLFMFQLSQFVWTALSNTKFLRARPQLSNVVFSFGVCSGPSIIMTLYLTL
What is the function of this protein?
Sterol O-acyltransferase that catalyzes the formation of stery esters.
What are the official names of this protein?
Sterol O-acyltransferase 1, Sterol-ester synthase 1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LEUC_FRAAA
Sequence: MGRTLAEKVWDAHVVRRADGEPDLLYIDLHLVHEVTSPQAFEALRLAGRPLRRPDLTLATEDHNVPTTNTLAPIADPISAAQVEALRKNCAEFGVRLYPMNDPGQGIVHVVGPQLGLSQPGMTIVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPQSRPKTMAVTVDGDLPAGVTAKDLILAIIARIGTGGGAGHVIEYRGAAVRGLSMEGRMTVCNMSIEAGARAGMIAPDDTTFEYLAGRAHAATGPDWDQAVAYWRTLASDDDAVFDREVVIDAASLTPYVTWGTNPGQAAPLGSLIPAPADYADPAARASVERALTYMGLTAGTPLSEVTVDTVFIGSCTNGRLSDLRAAADVLRGRRVADGVRALVVPGSMQVKAEAEAEGLDEVFRAAGAEWRSAGCSMCLGMNPDTLRPGERSASTSNRNFEGRQGPGGRTHLVSPAVAAATAVTGQLTAPAQL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RS8_MYCPU
Sequence: MSIITDPIADMLTRIKNATKRKHKSVNIPFSNKKLKIVEIIKKEGYISGYEIVGQGIEKKILITLKYKGNTSAIFDLKRISKPGLRVYTTASNIPSVLSGYGIAIISTSKGILTDKEARKENVGGEVIAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.