PharMolix/UniProtQA huggingface dataset:
Protein: NCLX_HUMAN
Sequence: MAGRRLNLRWALSVLCVLLMAETVSGTRGSSTGAHISPQFPASGVNQTPVVDCRKVCGLNVSDRCDFIRTNPDCHSDGGYLDYLEGIFCHFPPSLLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWIYQRQRRGSLFCPMPVTPEILSDSEEDRVSSNTNSYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKALKVFKLPVEFLLLLTVPVVDPDKDDQNWKRPLNCLHLVISPLVVVLTLQSGTYGVYEIGGLVPVWVVVVIAGTALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGVIHLKSM
What is the function of this protein?
Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, by mediating the exchange of 3 sodium ions per 1 calcium ion (PubMed:20018762, PubMed:22829870, PubMed:23056385, PubMed:24898248, PubMed:28219928).  Plays a central role in mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion: calcium efflux is essential for mitochondrial function and cell survival, notably in cardiomyocytes (By similarity).  Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses (PubMed:23056385).  Required for store-operated Ca(2+) entry (SOCE) and Ca(2+) release-activated Ca(2+) (CRAC) channel regulation: sodium transport by SLC8B1 leads to promote calcium-shuttling that modulates mitochondrial redox status, thereby regulating SOCE activity (PubMed:28219928).  Involved in B-lymphocyte chemotaxis (By similarity).  Able to transport Ca(2+) in exchange of either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange (PubMed:15060069).  In contrast to other members of the family its function is independent of K(+) (PubMed:15060069).
What are the official names of this protein?
Mitochondrial sodium/calcium exchanger protein, Na(+)/K(+)/Ca(2+)-exchange protein 6, Sodium/calcium exchanger protein, mitochondrial, Sodium/potassium/calcium exchanger 6, Solute carrier family 24 member 6, Solute carrier family 8 member B1.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL4_DESRM
Sequence: MPKVALYNINGEQVGEVELKDEVFGIEPHEHVMHEAVNMQLANQRQGTHDTKTRAEVRGGGRKPWRQKGTGRARAGSSRSPIWRKGGIVFGPHPRDYAISLPKKVRRLALKSALSSKVLDQNIIVLDSLTMDAPKTKDMVRILGNLKADKALVVTATRDLNVEKSARNIEGVKPLKADGVNVYDLLKYTKLVITKDAVAKIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y1729_BRUA2
Sequence: MAGHSQFKNIMHRKGRQDAVRSKMFSKLAREITVAAKQGLPDPAMNPRLRLAIQNAKAQSMPKDNIERAIKKAAGNDGENYDEVRYEGRGPGGVSVIVEALTDNRNRTASNVRAAFTKSGGSLGETGSVSFMFDRVGEIVYKPEAGDADKVMEAAIEAGAEDVQSGEDGHVILCAFEDIGEVSKALEAALGEAESIKTIWKPQTNTELDEEKARSVLKLLSVLEDDDDVQNVYTNFEVSDEVMEKLSA
What are the official names of this protein?
Probable transcriptional regulatory protein BAB1_1729.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTSA_SALTI
Sequence: MSRLVVVSNRIAPPDNKGGAGGLAVGVLGALKAAGGLWFGWSGETGNEDEPLKKVTKGNITWASFNLSEQDYEDYYCQFSNAVLWPAFHYRLDLVQFQRPAWEGYMRVNALLADKLLPLIKENDIIWVHDYHLLPFASELRKRGVNNRIGFFLHIPFPTPEIFNALPPHDELLEQLCDFDLLGFQTENDRLAFLDSLSSQTRVTTRSGKQHIAWGKDFQTEVYPIGIEPDEIALQAAGPLPPKLAQLKAELKNVKNIFSVERLDYSKGLPERFLAYEALLENYPQHRGKIRYTQIAPTSRGEVQAYQDIRHQLETEAGRINGKYGQLGWTPLYYLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEFVAAQDPANPGVLVLSQFAGAANELTSALIVNPYDRDDVAAALNRALTMPLAERISRHAEMLDVIVKNDINRWQERFIHDLKEVTPRSPERQQQNNVATFPKLA
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose.  Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Acts with retention of the anomeric configuration of the UDP-sugar donor.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: FRDD_PHOPR
Sequence: MVNLNPKRSDEPVWWGLFGAGGTWFAMLTPVTILVLGIMVPLGILDADAMSYERVSGFVTSFIGALFTIATLALPMWHAMHRLHHGMHDLKFHTGVVGKIACYATAFLVSALAIIFVFMI
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PMT4_YEAST
Sequence: MSVPKKRNHGKLPPSTKDVDDPSLKYTKAAPKCEQVAEHWLLQPLPEPESRYSFWVTIVTLLAFAARFYKIWYPKEVVFDEVHFGKFASYYLERSYFFDVHPPFAKMMIAFIGWLCGYDGSFKFDEIGYSYETHPAPYIAYRSFNAILGTLTVPIMFNTLKELNFRAITCAFASLLVAIDTAHVTETRLILLDAILIISIAATMYCYVRFYKCQLRQPFTWSWYIWLHATGLSLSFVISTKYVGVMTYSAIGFAAVVNLWQLLDIKAGLSLRQFMRHFSKRLNGLVLIPFVIYLFWFWVHFTVLNTSGPGDAFMSAEFQETLKDSPLSVDSKTVNYFDIITIKHQDTDAFLHSHLARYPQRYEDGRISSAGQQVTGYTHPDFNNQWEVLPPHGSDVGKGQAVLLNQHIRLRHVATDTYLLAHDVASPFYPTNEEITTVTLEEGDGELYPETLFAFQPLKKSDEGHVLKSKTVSFRLFHVDTSVALWTHNDELLPDWGFQQQEINGNKKVIDPSNNWVVDEIVNLDEVRKVYIPKVVKPLPFLKKWIETQKSMFEHNNKLSSEHPFASEPYSWPGSLSGVSFWTNGDEKKQIYFIGNIIGWWFQVISLAVFVGIIVADLITRHRGYYALNKMTREKLYGPLMFFFVSWCCHYFPFFLMARQKFLHHYLPAHLIACLFSGALWEVIFSDCKSLDLEKDEDISGASYERNPKVYVKPYTVFLVCVSCAVAWFFVYFSPLVYGDVSLSPSEVVSREWFDIELNFSK
What is the function of this protein?
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity.  Forms a homodimeric complex to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins.  Specifically acts on secretory proteins with an ER-luminally oriented Ser/Thr-rich region flanked by a membrane anchor such as FUS1, AXL2, GAS1, KEX2, MID2, WSC1, WSC2, OPY2, PRM5, RAX2, or YNL176.
What are the official names of this protein?
Dolichyl-phosphate-mannose--protein mannosyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YP68_CAEEL
Sequence: MTDQMRDMIAQLMGSQHVDNKEKPSMPFDHHSVCRAFLLGVCPHDMVPDSRLQNVVSCRKVHEPAHKADYERAQKEKDHFYDVDAFEIIEHAVHLVDIEIAKVREKLEDDVKTQTSQAADSKAKQVAEIEEKIAKNVDDIEKLGNEGKIEESMKLHKYVEELREKIQEIEDSQTEVKTAGPGSNSAKLRVCEDCGAQLNITDHESRIADHYNGKMHIGMVETRETYLKMKETIDERRKEREEKLGSQRGYQRRESYGRRDRGGDRGEYRGDRDRDRRNRDRSRSRDRSYRRDDRGDRRYDRDNRDRRDRDRRY
What are the official names of this protein?
Uncharacterized protein B0495.8.
What is the protein family that this protein belongs to?
Belongs to the Luc7 family.
Protein: CO1A1_GLYSX
Sequence: GGVSVPGPMGPSGPRGLPGPPGSPGPQGFQGPPGSSGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKQMGPRGLPGERGRPGASGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGAPGPKGNSGEPGAPGNKGDTGAKGEPGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGIAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPAGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGNGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGAPGKDGVRGLTGPIGPPGPAGAAGDKGETGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGPPGPIGNVGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKEGGKGPRGETGPAGRPGEVGPPGPPGPGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGSSGERGPPGPMGPPGLAGPPGEAGREGSPGAEGSPGRDGSPGPKGDRGETGPGPPGAPGAPGAPGPVGPAGKSGDRGETGPSGPAGPAGPAGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPAGPPGSPGEQGPSGASGPAGPRGPPGSAGTPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: NADE_STRT2
Sequence: MTLQETIIAQLGVKPSINPKEEIRKSVDFLKAYMIKHPFLKTYVLGISGGQDSTLAGRLAQLAVEELRAETEKDYQFIAIRLPYGVQADEDDAQRALAFIKPDVSLTINIKEAVDGQVAELAKAGVNVSDFNKGNIKARQRMITQYAVAGENSGAVIGTDHAAENLTGFFTKFGDGGADILPLFRLNKRQGAALLAELGADKALYEKVPTADLEEDKPGIADEVALGVTYHEIDDYLEGKEVSAKAQETIETWWRKGQHKRHLPITIFDDFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: HISX_RHIME
Sequence: MAIRLNYLDTSFERDFAAFLTTKREVSEDVNAVVRAIIDDVRARGDAALADYSARFDGIDFTVTGMAVTSAEIDAAIHAVAPEVLGALKVAATRIEAHHRRQLPKDDIYEDQMGVGLGSRWTPIDAVGLYVPGGTASYPSSVLMNALPAKVAGVPRIVMVVPASGGSINPAVLAAARLAGVEEIYRIGGAQAVAALAYGTETIEPVAKIVGPGNAYVAAAKRQVFGTVGIDMIAGPSEVLVIADRDNDPDWIAADLLAQAEHDAGAQAILITDDAAFGDAVEKAVERQLKTLPRAETAAASWRDFGAVILVPDFDKAVPLANRIAPEHLELATADPDAMVPAIRNAGAIFIGRHTPEVIGDYVGGSNHVLPTARSARFSSGLGVLDYVKRTSILRLGPDQLRILGPAAIALARSEGLEAHARSVAIRLNLGEEG
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: DCE2_CANLF
Sequence: MASPGSGFWSFGSEDGSGDPENPSTARAWCQVAQKFTGGIGNKLCALLYGDAEKPAESGGSEPPRATSRKAACACNQKPCSCPKAEVNYAFLHATDLLPACDGERPTLAFLQDVMDILLQYVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILMHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMLIARFKMFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMVPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHIDKCLELAEYLYSIIKNREGYEMVFDGKPQHTNVCFWYVPPSLRVLEDNEERMNRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL
What is the function of this protein?
Catalyzes the production of GABA.
What are the official names of this protein?
Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasmic vesicle. Presynaptic cell membrane; Lipid- anchor. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters (By similarity).
Protein: KXDL1_XENLA
Sequence: MAEQVTEATASGVFCSRILNMVNTGDVNAIILAQRHMLDRFEKTNEMLLNFNGLSNVRLQQMSDRFAHHTRTLVEMKKDLDIIFRRIRMLKGKLAKQYPESFNNVHESPILEDDDDFDPTLKSAATTIATSEQSTESCDTSPSIISPAMSQDFEDLSQAPSDTPSVNGQILTDEELVHED
What is the function of this protein?
As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor.  May also be involved in the biogenesis of lysosome-related organelles such as melanosomes.
What are the official names of this protein?
KxDL motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the KXD1 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: RISB_STAAU
Sequence: MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNEDNIDVAFVPGAFEIPLVAKKLASSGNYDAIITLGCVIRGATSHYDYVCNEVAKGVSKVNDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: AACUJ_ASPA1
Sequence: MTIRALNQNIPPWTFAANADEQGPTHPFSSPHPNPNTWAFQPAPNKVGRPGHPYPSPWAAQPRDGDDTNEANHERGEATAPRKPYPYPGPAKGHPPYSFPGAPEARKPYPFPIYAQEPHTYPGPLPWHQPHVYPGPAEDRKPYPSPWVDDDGAKPKPFPRKPYPYPGPAEGHKPYPYPGAIPWRQPYPSPWADDNDDDDDDHKGKPTFPRQPYQPYQFPGAQTHGAGGFPYHQPPDTFPGFQQGGSRGRGWGANGYSARTSFDTPHHPWGFPLLYSNQPPFTFPGVKSDAYQLDVDVFDTPEAFVIHVPLPGAKKEDVEVSWDPKAVQLGISGTIGRPGSEELLKTIALDERRVGAFERKVRLGGPGSAPKVDGEAISAKLEDGVLVVEVPKTEPDDVEVKKVVI
What is the function of this protein?
SHSP domain-containing protein; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer secalonic acid D (PubMed:30996871, PubMed:33891392).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase AacuL (Probable).  The atrochrysone carboxyl ACP thioesterase AacuM then breaks the thioester bond and releases the atrochrysone carboxylic acid from AacuL (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase AacuI, and oxidized by the anthrone oxygenase AacuG to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by a yet unidentified oxidoreductase (Probable).  A-ring reduction by the short chain dehydrogenase AacuN, dehydration by the scytalone dehydratase-like protein AacuK and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:33891392).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) AacuH then yields monodictyphenone (PubMed:33891392).  Monodictyphenone is transformed into compounds with the tetrahydroxanthone skeleton via methylesterification by the methyltransferase AacuQ, followed by the action of the flavin-dependent monooxygenase AacuC, the isomerase AacuP, and the short chain dehydrogenase/reductase AacuF or AacuD (PubMed:33891392).  AacuF and AacuD should accept the same compound as a substrate but perform the ketoreduction with a different stereoselectivity, thus yielding blennolides B and A, respectively (PubMed:33891392).  In the final step of the biosynthesis, the cytochrome P450 monooxygenase AacuE accepts blennolide B and/or blennolide A to conduct the dimerization reaction to furnish the tetrahydroxanthone dimers, secalonic acids D, B, and F (PubMed:33891392).
What are the official names of this protein?
SHSP domain-containing protein AacuJ, Secalonic acid cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: NADK_HELHP
Sequence: MKSHNAPITKVGVILRPSSPELKTTFLQIKEELNNAGIEVILESISGGMIELLGRDFHQLATQCDALFSLGGDGTLISMLRRAFEYELPCMGINTGRLGFLTALMPQNLHTFTSHLKSGDYTLQKHLVLQARIYSTLNTAYENNLDNKNQTPTQTLIAINEFLISKHELSGMVHIDASIDRKYFNTYRCDGLIIGTPAGSTAYNISAGGSVIYPYCRNILLTPIAPHSLTQRPLVLSDEFMLEFYAKERAKLIIDGQEMIDIMPSDRVQIQALPQSAMLMYPPTRDYFSVLKEKFKWGEEH
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMG1_BOVIN
Sequence: MGRIFLTGEKANSVLKRYPRANGLFEEIRQGNIERECKEEVCTFEEAREAFENNEKTKEFWNTYTKAQQGESNRGSDWFQFYLTFPLIFGLFIILLVIFLIWRCFLRNKTRRQTVTESHIPFPQHLNIITTPPPPDEVFDNSGLSPGFLEYVVGRSDSVSTRLSNCDPPPTYEEATGQMNLRRSETEPHLDPPPEYEDIINSNSASAIAMVPVATTIK
What are the official names of this protein?
Transmembrane gamma-carboxyglutamic acid protein 1, Proline-rich gamma-carboxyglutamic acid protein 1, Proline-rich Gla protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: FLIW_CAMLR
Sequence: MNLEVKCPILGFEDTKNMNFYKIDEVFYRLKSLDGKDFSFVMIDPYMIRPDYDFEVPDYYQELLALNEQTNFGVFVIVAINEPLEESTVNFLAPVVMNYDNNSLVQVILDTSKYPNYFQSEKISAFIKQTK
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_RHOP2
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRRYATVGDVIVVSIKEAIPRGKVKKGDVMKAVVVRVRKDIRRPDGSVIRFDRNAAVLINNQSEPVGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GGS4_PHOAM
Sequence: MDFPIRSQARLYPAQCVTFCLYVRVPPLSEWNFLKMQTDARPSATWPSVPKVHKRNRSTSLSDQQTAKKAHANHARLHLPQPIEPVYESQNGSVSQSEEKSSAVEINNSAAGDPQRFAVADLNFSWAEEEEKVVLAPYDYVASNSGKEFRTLILNAFNAWFRVPPESLTIICDVVRMLHTSSLLIDDIQDNSLLRRGRPVAHSIYGVAQTINTGNYVYFLAAKELNKLRNAASALEVFTAEMLNLHRGQGQELYWRDTLKCPTEDEYLKMVSNKTGGLFRMAVKLMQAESPAGPMAPVCDKLVQLLGLVYQIADDYKNLTAVEYTTSKGFCEDLTEGKFSFPVVHSIQSRPEDRRLYQILAQKTTEVEVKKYAVSYIESTGSLEYTKQVVRVLVQRARDELSRIDQGRERNQEMHALLGKMALE
What is the function of this protein?
Catalyzes the trans-addition of the 3 molecules of isopentenyl diphosphate (IPP) onto dimethylallyl diphosphate (DMAPP) to form geranylgeranyl pyrophosphate (GGDP).
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase D, GGPP synthase D, GGPPSase, (2E,6E)-farnesyl diphosphate synthase D, Dimethylallyltranstransferase D, Farnesyl diphosphate synthase D, Farnesyltranstransferase D, Geranylgeranyl diphosphate synthase D, Geranyltranstransferase D.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_THEKO
Sequence: MSDSKDELIRMFFDEEAILFGRFILTSGKESNYYINVKKLSTKPRALKLIAKLMAGEAQKRGITFDRVAGPELGAVPIATALALETEKPLVIVRKKPKGHGTGSQLEGEVKAGDKVLLVEDVTTTGGSVLRAAEVLEREGAEIAAIMVVVDREEGAEETIGAKYTFLPLVRVSELFARRKEPQKE
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LTG20_ARATH
Sequence: MSKIISLVVAMIAVLALPIRGQQQPLSQCTPSMMTTVSPCMGFITNSSSNGTSPSSDCCNSLRSLTTGGMGCLCLIVTGTVPFNIPINRTTAVSLPRACNMPRVPLQCQANIAPAAAPGPAATFGPSMSPGPETDPIVPEPTPAAQTPQSDTTRPFTPSVDGGAPTSDDGGSTSRPSETPSSAYALSPSLLFFSIALVALKFY
What is the function of this protein?
Probable lipid transfer protein.
What are the official names of this protein?
Non-specific lipid transfer protein GPI-anchored 20, AtLTPG-20, Protein LTP-GPI-ANCHORED 20.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: RRF_CHLTR
Sequence: MTLASAEKEMVGVLTFFQKETRGFRTGKAHPALVETVTVEVYGTTMRLSDIASISVSDMRQLLLSPYDAGTVSAISKGILAANLNLQPIVEGATVRINVPEPTEEYRREVIKQLKRKSEEAKVAIRNIRRTFNDRLKKDDNLTEDAVKSLEKKIQELTDKFCKQIEELAKQKEAELATV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_SALG2
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSNPASQIYVASKRKACDEVGFVSRSYDLPETTSEAELLALIDTLNADNTIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDLRHHVEHADLLIVAVGKPGFIPGEWIKEGAIVIDVGINRLENGKVVGDVVFDEAAARASYITPVPGGVGPMTVATLIENTLQACIEYHDPQGK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HXB2A_TAKRU
Sequence: MNFEFEREIGFINSQPSLAECLTSFPAVLESFQTSSIKESTVIPPPFEHTIPSLSPCAASQPRPTARNQQNRRNSNTNGIQTHQRAAQQPCPPGQAPATATAAGPMAPEFPWMKEKKSSKKSSKPGSSSGGGAPILPPSSASPSPTASGYASASIESPTDQSQAGLDAGGAGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTHHRDGSGGGNDSNEPGGFEPLEGADASSPYSSQPLEASGTGESESEQGSSNPSSAAYASDSGDNAQSTAEEGGLLGCPDRQSLSAVSGSSATHLHPLTATNSSDNQAPLQLNRTGPEPSFSEQRDSSIPSATAALPDLTLFATDACLSPSLQSSLDSPVDFSEEDFDLFTSTLCTIDLQHLNF
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B2a.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Proboscipedia subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLIT_ECOSM
Sequence: MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEIDPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLS
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.