PharMolix/UniProtQA huggingface dataset:
Protein: RIMO_PSELT
Sequence: MKIGIKVLGCPKNEADCDVLEAILKDRGHEIVSDIEEAEAVIIDTCGFIESAKKESIDEIITFANYKKYRPFFLCVKGCLVQRYSKELSKEIPEVDSWLGVLSPHQIAEAIEKATPYLVEKPTVVYEEAPRSCNNSFAYVKIADGCDRSCTFCSIPLFKGRFKSRSIESIYSEVERLVEIGVKEIILVAQDTTAYGVDLYNKAVLDQLLKKLNSIEGNFRIRVMYLHPDHLTDKMIDAICSLDKLLPYFDIPVQHGSDRILKQMGRIKNSEQLLELIAYIRSHNPDAAIRTSVMVGFPGETNDDFQKLLDFLEKAKFDRLGCFIYSDEEGTVSSSMKRKVSERIARERYENLLIFQSQIAYERLKRFVGKNLNVLIEQENELFYVARSHLDAPEVDGEVTVKKTREVDIPGYYTVRITDSDEYDLKGELI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLGN3_HUMAN
Sequence: MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
What is the function of this protein?
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members.  Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins.  May promote the initial formation of synapses, but is not essential for this.  May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).
What are the official names of this protein?
Neuroligin-3, Gliotactin homolog.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Synapse. Note=Detected at both glutamatergic and GABAergic synapses.
Protein: CYC_EUGVI
Sequence: GDAERGKKLFESRAGQCHSSQKGVNSTGPALYGVYGRTSGTVPGYAYSNANKNAAIVWEDESLNKFLENPKKYVPGTKMAFAGIKAKKDRLDIIAYMKTLKD
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: ERV29_YEAST
Sequence: MSYRGPIGNFGGMPMSSSQGPYSGGAQFRSNQNQSTSGILKQWKHSFEKFASRIEGLTDNAVVYKLKPYIPSLSRFFIVATFYEDSFRILSQWSDQIFYLNKWKHYPYFFVVVFLVVVTVSMLIGASLLVLRKQTNYATGVLCACVISQALVYGLFTGSSFVLRNFSVIGGLLIAFSDSIVQNKTTFGMLPELNSKNDKAKGYLLFAGRILIVLMFIAFTFSKSWFTVVLTIIGTICFAIGYKTKFASIMLGLILTFYNITLNNYWFYNNTKRDFLKYEFYQNLSIIGGLLLVTNTGAGELSVDEKKKIY
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.  The C-terminal di-lysine motif is required for exit from the endoplasmic reticulum.  Required directly for packaging glycosylated pro-alpha-factor into COPII vesicles.  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum.
What are the official names of this protein?
ER-derived vesicles protein ERV29.
What is the protein family that this protein belongs to?
Belongs to the SURF4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AGUA_YERPE
Sequence: MLQQQALPGTPRQDGFFMPAEWAPQDAVWMLWPYRQDNWRGKAIPAQQTFAKVAEAISRATPVFMGVPAEFMAQAKATMPANVTLVEMASDDAWMRDTGPTMVINGAAERRAVDWQFNAWGGLNGGLYADWQQDEKVAVQVSDFLKNAHYSAPLILEGGSIHTDGEGTLLTTAECLLNPNRNPHLNQAQIEQLLCDYLGVTHFIWLQDGVYNDETDGHIDNMCCFVRPGEVALHWTDDQQDPQYARSVAAFEVLSNTVDAKGRKLKIWKLPAPGPLYNTEEETFDVLTSDAVPRTAGERLAGSYVNFLISNQQIIFPLLDSRTDGQANDLLQQMFPGYAIVGVPAREILLGGGNIHCITQQIPAA
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: HTF_PERBR
Sequence: QVNFSPNW
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, PerBr-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: EASF_ARTBC
Sequence: MGSINPPQILDIRRSKFEESIPKQVEAGLLSSPKTLPALLFYSTEGIQHWNRHSHASDFYPRHEEIQILKDKATDMAASIADGSVVVDLGSASLDKVIHLLEALEAAQKKVTYYALDLSFSELTSTLQAIPTDQFVHVQFSALHGTFDDGLQWLKETPVIRDQPHCLLLFGLTIGNFSRSNAAKFLHNIASHALVESPSQSSILLTLDSCKVPTKVTRAYTAEGVVPFALESLKYGNTLFQQDGGENVFDPEDWYFLSEWNYVLGRHEASLVPRSKDIKLGRPLDKIVVGKHEKVRFGCSYKYDSEERKELFGTAGLRDVKSWSKEGCDVAFYQLKCCPN
What is the function of this protein?
4-dimethylallyltryptophan N-methyltransferase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid (PubMed:22403186).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:22403186).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (PubMed:22403186).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:22403186).  Chanoclavine-I aldehyde is the precursor of ergoamides and ergopeptines in Clavicipitaceae, and clavine-type alcaloids such as fumiclavine in Trichocomaceae (PubMed:22403186).  However, the metabolites downstream of chanoclavine-I aldehyde in Arthrodermataceae have not been identified yet (PubMed:22403186).
What are the official names of this protein?
4-dimethylallyltryptophan N-methyltransferase easF, 4-dimethylallyltryptophan methyltransferase, Ergot alkaloid synthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: CDD_VIBVU
Sequence: MKSRFENALASAPESLSRHLAPIILAADFDASLSTVQFDELLKQTGMTDNQLRVALLPFAAAYSYAPISEFYVGAIVRGLSGALYFGANMEFDGVQLGQTVHAEQSAISHAWMKGEQGLSDITINFSPCGHCRQFMNELSSAKELKIQLPEREEKKLHDYLPDSFGPSDLGIESALMSQVHHGFATEDDDALMQRAVEAMNRSHAPYTHNLSGVALQTESGRVYLGAYAENAAFNPSLPPLQVALIQLLLAGERFENIQSAALVESHKGKISHLACTQSTLEALNPDIPVSYLSL
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: PMT2_YEAST
Sequence: MSSSSSTGYSKNNAAHIKQENTLRQRESSSISVSEELSSADERDAEDFSKEKPAAQSSLLRLESVVMPVIFTALALFTRMYKIGINNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEIYPDYLDYVKMRLFNASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGRFILLDSMLLFFTVASFFSFVMFHNQRSKPFSRKWWKWLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDLLSHSGTGDANMPSLFQARLVGSDVGQGPRDIALGSSVVSIKNQALGGSLLHSHIQTYPDGSNQQQVTCYGYKDANNEWFFNRERGLPSWSENETDIEYLKPGTSYRLVHKSTGRNLHTHPVAAPVSKTQWEVSGYGDNVVGDNKDNWVIEIMDQRGDEDPEKLHTLTTSFRIKNLEMGCYLAQTGNSLPEWGFRQQEVVCMKNPFKRDKRTWWNIETHENERLPPRPEDFQYPKTNFLKDFIHLNLAMMATNNALVPDPDKFDYLASSAWQWPTLNVGLRLCGWGDDNPKYFLLGTPASTWASSVAVLAFMATVVILLIRWQRQYVDLRNPSNWNVFLMGGFYPLLAWGLHYMPFVIMSRVTYVHHYLPALYFALIILAYCFDAGLQKWSRSKCGRIMRFVLYAGFMALVIGCFWYFSPISFGMEGPSSNFRYLNWFSTWDIADKQEA
What is the function of this protein?
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity.  Forms a heterodimeric complex with PMT2 and more rarely with PMT5 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins.  The PMT1-PMT2 complex participates in oxidative protein folding, ER-associated protein degradation (ERAD), as well as ER export.
What are the official names of this protein?
Dolichyl-phosphate-mannose--protein mannosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RISB_XANC8
Sequence: MTHYEGDLRPTTARFVIIASRWNARITDALVTGARQSLAGNGIGEDAIDVVRVPGAWEIPMAANRVAQGGQHAAIIALGCVIRGDTRHYEHVADLCAEGLMSVQLQTGVPVLNGVLAVERVEDAEARAGGSHGNKGEECALAALELVNLMELLP
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: NET1C_ARATH
Sequence: MEIAAKSNSKRMYSWWWDSHNTPKNSKWLQDNLADMDSNVKQMIKVLEEDADSFARRAEMYYRKRPELMKLVEEFYRAYRALAERYNHATGVIHKAHETIAEAFPNQVPLIFGDESHGGALTNDVDPQTPDMPPPFRARGNPDEFQQDALGFSLSHVHDVKRNIDFSEEPLFVSNGKARKGLNFNDHGDGKGRNGLKDHILSESERASKAEAEVVALKDSLSKMQAEKQASLALFEKNLERLSNLESEVSRAQADSRGINDRAASAEAEIQTLRETLYKLESEKESSFLQYHKCLQKIADLEDGLSVAHKEAGERASKAETETLALKRSLAKAETDKETALIQYRQCLNTISNLEERLRKAEEDARLINERAEKAGVEVENLKQTVSKLIKDKEASELQFQQCLNIIASLKVKLHHAQEETQSLSHEIEDGVAKLKFSEEKCLLLERSNQNLHSELDSLLEKLGNQSQKLTEKQTELVKLWSCVQAEHLHFQEAETAFQTLQQLHSQSQEELNNLAVELQTVSQIMKDMEMRNNELHEELEQAKVENKGLNDLNFTMEKLVQKNLMLEKSISYLNSELESFRRKLKTFEEACQSLSEEKSCLISENQHNVIENTVLIEWLRQLRLEAVGIATEKTDLEGKAKTIGDKLTDAETENLQLKRNLLSIRSEKHHLEDEITNVKDQLHEKEKEFEEIKMEKEKLIQEVFKERKQVELWESQAATFFCDKQISVVHETLIEATTRELAEACKNLESKSASRDADIEKLKRSQTIVLLNESIKSLEDYVFTHRESAGEVSKGADLMDEFLKLEGMCLRIKAIAEAIMEKEKFLMLENTNTYSMLEASLKQIKELKTGGGRSMRKQDGGSGRMRKQSHETEMVMKDIVLDQTSDGSSYEIVSKKGNSELDHLGFVELKPVKTHKTETKALSEESLIVEKVEIFDGFMDPNREVNKRRVLERLDSDLQKLENLQITVEDLKSKVETVEKEKTKVGENEYKTIKGQLEEGEEAIEKLFTVNRKLTTKAESEKDIDRRRRIFEHARRGTEKIGRLQSEIQRIQFLLMKLEGEREHRLRSKISDTKVLLRDYIYGRTRSVSMKKRTKKRSVFCGCVQQPESP
What is the function of this protein?
Plant-specific actin binding protein.  May be part of a membrane-cytoskeletal adapter complex.
What are the official names of this protein?
Protein NETWORKED 1C.
What is the protein family that this protein belongs to?
Belongs to the NET family.
Protein: FABH_DINSH
Sequence: MGKRAVVTGVGHYLPSRVVPNSELETLVDTTDEWIRTRSGIERRHFAADGEQTSDLATAAAQAALDHAELTAQDVDAVIVATSTPDLTFPAVATMVQARLGMTRGFAYDVQAVCAGFVFAMANANAMILSGQADRILVIGAETFSRIMDWTDRSTCVLFGDGAGAVVLEARDGTGGTADRGILSADLNSDGRHRDILYVDGGVSSSQTAGYLRMEGKEVFRHAIEKLAATAETALAKAGLTEADVDWVVPHQANLRIITATARKMGIGMDRVVVTVADHGNTSAASIPMALSVGVARGQIKPGDLVVTEAIGGGLSWGSVVLRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TERL_BPLSK
Sequence: MYYLNKMLEYNKENGIIINKYIRKTIQKQIRIHNKYIYRYDRVTQAIEWIEDNFYLTTGNLMKIELLPTQRWWYELMLGYDMIDEKGVQVNLINEIFLNLGRGSGKSSLMATRVLNWMILGGQYGGESLVIAYDNTQARHVFDQVRNQTEASDTLRVYNENKIFKSTKQGLEFASFKTTFKKQTNDTLRAQGGNSSLNIFDEVHTYGEDITESVNKGSRQKQDNWQSIYITSGGLKRDGLYDKLVERFKSEEEFYNDRSFGLLYMLENHEQVKDKKNWTMALPLIGSVPKWSGVIEEYELAQGDPALQNKFLAFNMGLPMQDTAYYFTPQDTKLTDFNLSVFNKNRTYVGIDLSLIGDLTAVSFVCELEGKTYSHTLTFSVRSQYEQLDTEQQELWTEFVDRGELILLDTEYINVNDLIPHINDFRTKTGCRLRKIGYDPARYEILKGLIERYFFDKDGDNQRAIRQGFSMNDYIKLLKSKLVENKLIHNQKVMQWALNNTAVKIGQSGDYMYTKKLEKDKIDPTVALTMALEMAVSDEV
What is the function of this protein?
The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction (By similarity).  The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities (By similarity).  Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine (By similarity).  The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer (By similarity).
What are the official names of this protein?
Terminase large subunit, DNA-packaging protein, Gene product 2, gp2.
What is the protein family that this protein belongs to?
Belongs to the skunavirus terminase large subunit family.
Protein: CH602_MYCGI
Sequence: MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEAVTQGLLKSAKEVETKEQIAATAAISAGDVQIGELIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDAERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIQAGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVVSEEVGLSLETADVALLGTARKVVVTKDETTIVEGAGDSDAIAGRVAQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQSAPVLEDLGLSGDEATGANIVRVALSAPLKQIAFNGGLEPGVVAEKVSNLPAGHGLNAATGEYEDLLKAGVADPVKVTRSALQNAASIAALFLTTEAVVADKPEKAAAPAGDPTGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Secreted, capsule. Cell surface. Secreted, cell wall.
Protein: GCH1_RICBR
Sequence: MTIKKPTKEEAKEAVRTLLRFIGEDPNREGLFKTPDRVIKSYEEIFSGYGKNIEEILETKFSDTGNFQDFISLEGIKFTSFCEHHMLPFSGTVHIAYIPDNCIVGISKLARIVNAFAKRLQIQEKMTVQIAESVQENLKPLGVAVKISALHSCMSMRGVMQDNSIMNTMHYTGIFAEQQKYRHEFLNLTSKK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: PYRH_ALKEH
Sequence: MSQPQYKRILLKLSGEALMGDAAYGISPDVIRRIAHEVAEVSRMGVEIALVIGGGNIFRGAGLAAAGMDRVTADHMGMLATVMNGLALQDALEHEGVYCRVMSAVKINQVCEDYIRRRAIRHLEKGRVVVFAAGTGNPFFTTDSAASLRAIEVGADIMLKGTKVDGVYSADPTRDPDARRYELLTYDQVLEDRLMVMDATAVVLCRDQNMRIMVFDITSPGALVDVITGQRTGTIVERGDEL
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPSF6_DROME
Sequence: MADVVLDLYAEDLDKDFAGQAQDEFGGDGVDLYDDIGGPTESAASGGGGGGTPSADGAAGPGSGEPGERNSGGPNGVYHQSSGSLTPTMNRRYQLYVGNLTWWTTDQDIANSLRDIGVSDLQEVKFFENRANGQSKGFSVISLGSESSLRAVLDQLPKKEMHGQAPVVTYPSKQALTQFESLQKTRPVPPPQQNGPPRGPAPPSMGGGPMPTGHPGGPQGGGPPGHPPRGMNSIMQPGQYRPQHMSQVPQVGGPNSGPPRMQPPMHPQGGLMGNQQPPPRYPSAQGQWPGQRPGGPRPGPPNGPPQRPMFQGGPMGMPVRGPAGPDWRRPPMHGGFPPQGPPRGLPPAPGPGGPHGAPAPHVNPAFFNQPGGPAQHPGMGGPPHGAPGPQPGMNMPPQQGMNMTPQHGPPPQFAQHGPRGPWPPPQGKPPGPFPDPQQMGPQLTEVEFEEVMSRNRTVSSSAIARAVSDAAAGEYSSAIETLVTAISLIKQSKVAHDERCKILISSLQDTLHGIEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGSYRERSRSRERERQAPDHYRDDSRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRREEHRSRH
What is the function of this protein?
May play a role in pre-mRNA 3'-processing.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 6.
What is the protein family that this protein belongs to?
Belongs to the RRM CPSF6/7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_LEPBA
Sequence: MVLLAASGFNLLKVNPGLVIWTLVTFSVVVFVLKKFAWDKILHALEERASGIQGDINKAESLRVEAEKSLKEYKDQLFKATEEAHRIVDEAKKDAVALRTKLTEEAHNEVKGIKDSAVREIELAKGRALSEIQNQIVEMSVLIASEILEKQLKKEDYASFVEKEIAKLDKLKIK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CLNK_MOUSE
Sequence: MTSQGNKRTTKEGFGDLRFQNVSLLKNRSWPSLSSAKGRCRAVLEPLPDHRRNLAGVPGGEKCNSNNDYEDPEFQLLKAWPSMKILPARPIQESEYADTRYFQDTMEAPLLLPPKASVSTERQTRDVRMTHLEEVDKPTFKDVRSQRFKGFKYTKINKTPLPPPRPAITLPKKYQPLPPAPPEESSAYFAPKPTFPEVQRGPRQRSAKDFSRVLGAEEESHHQTKPESSCPSSNQNTQKSPPAIASSSYMPGKHSIQARDHTGSMQHCPAQRCQAAASHSPRMLPYENTNSEKPDPTKPDEKDVWQNEWYIGEYSRQAVEDVLMKENKDGTFLVRDCSTKSKAEPYVLVVFYGNKVYNVKIRFLESNQQFALGTGLRGNEMFDSVEDIIEHYTYFPILLIDGKDKAARRKQCYLTQPLPLARLLLTQYSSQALHE
What is the function of this protein?
An adapter protein which plays a role in the regulation of immunoreceptor signaling, including PLC-gamma-mediated B-cell antigen receptor (BCR) signaling and FC-epsilon R1-mediated mast cell degranulation (PubMed:10562326, PubMed:10744659, PubMed:11509653, PubMed:12681493).  Together with FGR, it acts as a negative regulator of natural killer cell-activating receptors and inhibits interferon-gamma production (PubMed:15199160, PubMed:16439675).  Acts as a positive regulator of both T-cell receptor and natural killer T (NKT) cell receptor signaling in CD4-positive NKT cells (PubMed:16439675).  Together with MAP4K1, it enhances CD3-triggered activation of T-cells and subsequent IL2 production (PubMed:11509653).  May be involved in tumor necrosis factor induced cell death by promoting reactive oxidative species generation, and MLKL oligomerization, ultimately leading to necrosis (PubMed:26009488).  Involved in phosphorylation of LAT (PubMed:11463797).  May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells (PubMed:12681493).
What are the official names of this protein?
Cytokine-dependent hematopoietic cell linker, Mast cell immunoreceptor signal transducer.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BDBA_BPSPB
Sequence: MKKWIVLFLVLIAAAISIFVYVSTGSEKPFYNDINLTQYQKEVDSKKPKFIYVYETSCPPCQEIKPELNEVIKKEKLKVQALNIEEKENYNTEFLDKYNLNKTPTILYYKDGKEKDRLEGYRSASQIEKFFDKNGDR
What are the official names of this protein?
Disulfide bond formation protein A, Disulfide oxidoreductase A, Thiol-disulfide oxidoreductase A.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FNTB_SCHPO
Sequence: MDELSETQVMQNETATAVLPLLNGESQSFNLQKHLKYLTKMLDPLPSPFTVLDASRAWMVYWELSSLAILGKLDSSVCERAISSVRQLKGPSGGFCGGNGQDEHLLSTYASILSICLCDSTDAYSLIERDRLYDWLFSLKNPDGSFRVNNEGESDARSVYAAVCVSSLVGISMDDPLFEGTLQWLCKCQTYEGGLSGVPYAEAHGGYTFCALAAIALLGGLDNLNEIKLSTWLVQRQDPALYGFSGRSNKLVDGCYSWWVGASHVIVASGYGSASHKSLPNLFYNPEKLLGYILQCCQSTSGGLRDKPPKRPDQYHTCYCLLGLSSIAYDYRYHTSDGWSYKPSILHSSLSSLLPAHPIYCVPFGFEERIKSYFLSQESSKF
What is the function of this protein?
Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins.  The beta(cpp1) subunit is responsible for peptide-binding.
What are the official names of this protein?
Protein farnesyltransferase subunit beta, FTase-beta, CAAX farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit beta family.
Protein: MMP1_RAT
Sequence: DTLKSEKNADFKDLY
What is the function of this protein?
Cleaves collagens of types I, II, and III at one site in the helical domain.  Also cleaves collagens of types VII and X.  May play a role in the deterioration of the heart wall extracellular matrix proteins during the onset of dilated cardiomyopathy.
What are the official names of this protein?
Interstitial collagenase, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1, Myocardial collagenase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ASNA_BACMK
Sequence: MYQSLMTVRETQIAIKEVKTFFEDQLAKRLELFRVSAPLFVTKKSGLNDHLNGVERPIEFDMLHSGEELEIVHSLAKWKRFALHEYGYEAGEGLYTNMNAIRRDEELDATHSIYVDQWDWEKIVQKEWRTIDYLQKTVQTIYGIFKELEGHLFEKYPFLGKYLPEEIIFITSQELEDKYPELTPKDREHAIAKEHGAVFIIGIGDALRSGEKHDGRASDYDDWKLNGDILFWHPVLQASFELSSMGIRVDSKALDEQLTKTGEDFKREYDFHKGILEDVLPLTIGGGIGQSRMCMYFLRKAHIGEVQSSVWPDDLREACKKENIHLF
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSY_HALVD
Sequence: MFDGLKKKLNRFRNDVEETAEEKAEAAADEAESDADAEAESAPADTDNAAVEPEASEPAAADPDADAVGDADAGSEADAVDAADAPADAESSSAAVEADAESESESAATPEPDSEVDAGADTGDEPSGEPTADEVEPRESLASDAAKAALTEEDEDDSSGPGRLRRAAAFATGKVVIEEEDLEDPLWELEMALLQSDVEMQVAEEILETIREKLIGETRKQVESTGQLVSEALHDALYEVISVGQFDFDQRIAEADKPVTLIFTGINGVGKTTTIAKLAKYFEKQGYSTVLANGDTYRAGANEQIREHAEALDKKLIAHEQGGDPAAVIYDGVEYAEAHDIDIVLGDTAGRLHTSNDLMAQLEKIDRVVGPDLTLFVDEAVAGQDAVERARQFNDAAAIDGAILTKADADSNGGAAISIAYVTGKPILFLGVGQGYDHIEKFDPEQMVERLLGEDE
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.