PharMolix/UniProtQA huggingface dataset:
Protein: LLDD_PECAS
Sequence: MIISASTDYRAAAQRRLPPFLFHYIDGGAYGEHTLRRNTADLADIALRQRILKNMSDLSLETQLFGEKLAMPVVLAPVGLTGMYARRGEVQAARAAAQKGIPFTLSTVSVCPIEEVAPAIDRPMWFQLYVLKDRGFMRSALERAQAAGVKTLVFTVDMPTPGARYRDAHSGMSGPNAAARRMLQAVTHPQWAWDVGLNGKPHDLGNVSAYRGKPTTLEDYIGWLAANFDPSISWQDLAWIREFWKGPMIIKGILDPEDAKEAVRFGADGIVVSNHGGRQLDGVLSTAHALPAIADAVKGDITILADSGIRSGLDVVRMIALGADGVMLGRAFVYALAAAGEAGVVNLLNLIEKEMRVAMTLTGAKSIADITSDSLVQVTQRRLDGL
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MSRR_STAAM
Sequence: MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLIALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKNDGKISILVLGADKAQGGQSRTDSIMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPKLLRKTLDKNLGINPEYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFRHDPEGDFGRVRRQQQVMQTLKKEMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGLSFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAIKDFLDED
What is the function of this protein?
Involved in SarA attenuation.  Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors (By similarity).
What are the official names of this protein?
Regulatory protein MsrR.
What is the protein family that this protein belongs to?
Belongs to the LytR/CpsA/Psr (LCP) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: YXEF_BACSU
Sequence: MVIPLRNKYGILFLIAVCIMVSGCQQQKEETPFYYGTWDEGRAPGPTDGVKSATVTFTEDEVVETEVMEGRGEVQLPFMAYKVISQSTDGSIEIQYLGPYYPLKSTLKRGENGTLIWEQNGQRKTMTRIESKTGREEKDEKSKS
What are the official names of this protein?
Uncharacterized protein YxeF.
Protein: CYB_FICPA
Sequence: MALNLRKNHPLFKTINDALIDLPTPSNISAWWNFGSLLGICLITQIVTGLLLATHYTADTSLAFNSVAHMCRNVQFGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLNKETWNVGVVLLLLLMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIAGITLVHLTFLHETGSNNPLGIPADCDKIPFHPYYSTKDILGFALMLILLVALALFSPNLLGDPENFTPANPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLVPLLHTSKQRSLTFRPISQVLFWALVANLLILTWVGGQPVEHPFIIIGQLASLSYFTIILVLFPLAAVLENKMLNL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ROGFB_ARATH
Sequence: MVKAMEQEQETYKSRLFHFKNMNENSASRHVKSWSSDCAMRMDGSDNLDDDDNDMMMFRSQPGKCGSVDRPSLPIGGVTPNRNDKLPRVSSSDSMEALIILQAAMEQMKEKFSKLLLGEDMSGGGKGVSSALALSNAITNLAASAFGEQRRLEPMAVDRKTRWRREIGWLISVADYIVEFAPTQQTNKDGTSMEVMSTRQRTDLLCNIPALKKLDAMLLDCLDKFKDQDEFYYVKKDSPDSCETRNDEKWWLPAVKVPPNGLSEISRRFLQSQKECVNQVLKAAMAINAQVLSEMEIPESYLESLPKNGRASLGDVIYRMITVEMFDADQFLIEMDLSSEHKILDLKNRIEASIVIWKRKMVQKDTKSPWGSTVSIEKREQFEERAETILLLLKQGFPGISQSSLDISKIQFNRDVGLAILESYSRVLESLAHTVMSRIEDVLYADQLTQEPTNNAPSKNRYSLKENEKLREERLSFTEDMASGTLSDVMQWGNKNNEMKKESFFGDREKPLLSKVTGIMTNNKKSSYLDNLGAMRSPTARYS
What is the function of this protein?
Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP.  Functions as a light-signaling switch that functions in root growth and development through the activation of Rop in a phytochrome-dependent manner.  May act as a negative regulator of phytochrome-mediated primary root development.
What are the official names of this protein?
Rop guanine nucleotide exchange factor 11, AtRopGEF11, Phytochrome interacting RopGEF 1, Rho of plants guanine nucleotide exchange factor 11.
What are the subcellular locations of this protein?
Cytoplasm. Note=Interacts with PHYA and PHYB in the cytoplasm in darkness.
Protein: GLGB_DESHY
Sequence: MQSKIQKDSPLLTQEEMYLFNCGEFYYSYRKFGAHFLEHKGRWGTYFAVWAPQARQVSVVGDFNGWCGMNHSLQKWEEQGIWTLFIPGLPTGEIYKYEILTSSGESVLKADPYAFFSEVRPHTASVIYSLEDYSWGDQAWLAQRKTRNPKVLPLSSYEIHLGSWRRTEDGRFLNYAQLVTVLIPYVKSLGYTHIEILPLMEHPYDGSWGYQITGFYACTSRYGTPHDLMYLIDQCHQAGIGVILDWVPGHFCMDAHGLGKFDGSPLYEREVHEQWGTYKFDYSRSEVRSFLISNAVFWLDVFHVDGLRVDGVSSMLYLDYGKAKGAWQPNRYGGRENLEAVGFIKQLNATLHGLYPDALLIAEEATDWQGVTGPLDQEGLGFTFKWNMGWMNDTLRYIGLDFPERRSFHQLLTFPMMYAYAESYILPLSHDEVVHGKKSLLDKMPGDYGQKFAGLRGLTTYFMTSPGKKLLFMGGEIPQFIEWREDRELDWFLMDYEMHRKYHGFVQQLNGLYLREKALWEIDGDWTGFEWIDVHNHEQGVIVFCRKGKSFQDRLVVLINFQPYNYERYRIGVEMAKGYREILNTDSTDFGGWGMTNPGLLKVEGVPWHGREFSLEIRVPALGAMILKPELA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RS16_SHEB2
Sequence: MVTIRLARGGAKKRPFYNIVVADSRNARDGRFIERVGFFNPLARGQEETLRLDLARVEHWVSNGAAATERVAKLIKDARKATA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: FABZ_PROM2
Sequence: MEKKLSSENNQLSSEQILGLLPHRYPFALVDKVIEHIPGERAVAIKNVTINEPQFQGHFPERPLMPGVLIVESMAQVGGIIVTQMPDLPKGLFVFAGINNVKFRKPVLPGDQLIISCELLSIKRQRFGKVKGEAHVDGKLVCAGELMFSLVN
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_XANC5
Sequence: MLIEHERGFVLHVRAWRETSLLVEVLTEQHGRVGLLARGVQGPRKQALRAALQPLQLIQFSAVQRGELAQLRQAEALDTAPRLVGDTMLAGFYISELLLRLAPRNDPVPELYACYAQARTYLASDLPLAWGLRRFERDVLDGLGFAFDLQHDSDGQPIDPAARYRLDPQEGALRVLSERLAQDRRETVTGAALLALGEDVMPDADDMPGLRRSMRGVLLHHLGGRGLKSWQMLEDLARRR
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: ARCC_LATSK
Sequence: MTKRKIVVALGGNAILSTDASANAQIKAVKETVKQLVAFVKQGDQLIISHGNGPQVGNLLIQQAASDSEKTPAMPLDTVGAMSQGEIGYWMQNAFNEVLAEEGLALDVATIVTQTIVDAKDEAFQNPTKPIGPFYSEAEAKKQQSINPEAHFVEDAGRGWRRVVPSPRPIGIQEAPVIQKLVEGNVITISAGGGGVPVAKEGNKLRGVEAVIDKDFASEKLAELVGADMLIILTAVDNVYVNFNKPDQKKLTNVSVAELEDYIKDDQFAKGSMLPKIQTAIEYVNNRPDSKAIITSLDNVKNLLAHDAGTIITK
What are the official names of this protein?
Carbamate kinase.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_PANPS
Sequence: VLSSADKNNVKACWGKIGSHAGEYGAEALERTFCSFPTTKTYFPHFDLSHGSAQVQTHGQKVADALTKAVAHINDLPNALSDLSDLHAYKLRVDPVNFKFLSHCLLVTLACHHPEEFTPAVHASLDKFFSAVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DAPD_PSYWF
Sequence: MSLEQIIEQAFEKRAEYSPATMPQEVKDAVNSVLDQLDNGSLRVAEKKDGEWIVNQWAKKAVLLSFRLNDNYPMQTGEHVQFYDKVPTKFANWTEQQFVEAGVRVVPPAVARRGSFIAKGVVLMPSYTNIGAYVDEGAMIDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVYIGQSTKIYDRETGEITYGRVPAGSVVVSGSLPSKDGSHSLYCAVIVKKVDAQTRSKTSINELLRLA
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1490_MYCTU
Sequence: MSQCFAVKGIGGADQATLGSAEILVKYAQLADKRARVYVLVSTWLVVWGIWHVYFVEAVFPNAILWLHYYAASYEFGFVRRGLGGELIRMLTGDHFFAGAYTVLWTSITVWLIALAVVVWLILSTGNRSERRIMLALLVPVLPFAFSYAIYNPHPELFGMTALVAFSIFLTRAHTSRTRVILSTLYGLTMAVLALIHEAIPLEFALGAVLAIIVLSKNATGATRRICTALAIGPGTVSVLLLAVVGRRDIADQLCAHIPHGMVENPWAVATTPQRVLDYIFGRVESHADYHDWVCEHVTPWFNLDWITSAKLVAVVGFRALFGAFLLGLLFFVATTSMIRYVSAVPVRTFFAELRGNLALPVLASALLVPLFITAVDWTRWWVMITLDVAIVYILYAIDRPEIEQPPSRRNVQVFVCVVLVLAVIPTGSANNIGR
What are the official names of this protein?
Uncharacterized protein Rv1490.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AT326_ASPTN
Sequence: MAKPNQRHACDRCHGQKLRCIHSGGGPCVRCAKAKATCSWSQSLRSNRLKRHNVPISDVPLACAQLATQSTDPNTPQFGAYMSQPSSAGVDIDINLLQTQFTDSTPWALPAGRYPSPASQEMETYNVGHTEADLPTTADWMWPAVANGPVQTTPPANWQQAFNQEWAMMASQHPVATMNTPSRTSPVSDAVDPPNTVCLLATIRELSELNVDLYAHEATVPRPPASLDEPISWKNKDFAIDRTFHLSQRLIEIVNKRYPRYLETARMQTPEGTPERTSESSPSGPPLDQGSCLLVLSCYTRLIETYDRIFANMQGCLDRSSVTAREDYVNMPSVQVGSFSLPHSSSLQIVLILQLARQLLTRMGEIIKAVQPEKGTNSADVTLSESATGGLLLSSALETVSAEEDRLMKRITKLRSTLIELNIL
What is the function of this protein?
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of isoflavipucine (PubMed:21236704).
What are the official names of this protein?
Isoflavipucine cluster transcription factor ATEG_00326.
What are the subcellular locations of this protein?
Nucleus.
Protein: KUP_LATSS
Sequence: MKLATEKKTTRQKLSIAGMLITMGVVYGDIGTSPLYVMKSIVEGNGGIRNISQDFVVGSISLVFWTLMLMTTVKYVLIALRADNNGEGGIFALYTLIRKQAKWLVIPAIIGGATLLADGMLTPAVTVTTAIEGLKGLPINGNVLVSNQREVIILTVTILSVLFFIQKFGTDLIGKSFGPIMLIWFTFIGAIGVMNLMGDLTMLKALNPYYAIHLLFSPENKVGILILGSVFLATTGAEALYSDMGHVGRHNIYGSWPYIAACLVLNYFGQGVWLLQHKEVAAYQNMTDFNPFFEAMPAQLKIPAILLATVAAIIASQALISGSYTLVSEAIKLRLLPRIKVDYPAKLKGQLYISIVNWILWAVCLAVVFYFKNSAHMEAAYGLAITITMLMTTILLFHYLGRREKRWFLAYVVLLFFGAIETIFFIASAAKFMHGGYVTVLIAFVILFIMFVWYRSNSIKESNTFKSSTVSLLAYKRQLHDLRNETSLPLYTTNLVYLSKPQAEPRGKNMVKKNILYSILDKRPKRAQVYWFVAVNVTDEPYTAEYTVDTLGTDYIVSVQLYLGFKMEQKVNIFIRQIIHEMIHNGELPAQPQHYTTIPNREVGDFSFVIIQEDLSPETQIRAMDKVIVQIRLWLEKFTDTPASWFGLEYSDVFVERIPLVLGRQKAINKYHLKRRQEES
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVC_BRUMB
Sequence: MKETIRIIGIDPGLRRTGWGIVESLGNSLHFIGSGTVTSNAEMDLASRLCQLHEGLSKVLHEFMPHEAAVEHTFVNKDATATLKLGQARGIALLAPAQAGLPVAEYAPNAVKKAVIGVGHGEKQQIHMMVKVLMPRASFDTSDAADALAIAICHAHHRQSIVSARRMQALLAG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CTNA1_RABIT
Sequence: MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLDKGDKIAKESQFLKEELVAAVEDVRKQGDLMKSAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVNGISNAAQATTSDDASQHPGGSGGGELAYALNDFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSAIDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLFKEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMDENEFIDASRLVYDGIRDIRKAVLMIRTPEELDDSDFETEDFDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKSQGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEFKAMDSI
What is the function of this protein?
Associates with the cytoplasmic domain of a variety of cadherins.  The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.  Can associate with both E- and N-cadherins.  Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions.  In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components.  The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments.  Involved in the regulation of WWTR1/TAZ, YAP1 and TGFB1-dependent SMAD2 and SMAD3 nuclear accumulation (By similarity).  May play a crucial role in cell differentiation (By similarity).
What are the official names of this protein?
Catenin alpha-1.
What is the protein family that this protein belongs to?
Belongs to the vinculin/alpha-catenin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries.
Protein: KAD_BORA1
Sequence: MRLILLGPPGAGKGTQATFITQTYGIPQISTGDMLRAAVKAGTPLGIEAKKVMDAGGLMPDEIIIGLVKDRLAQPDCANGYLFDGYPRTIPQADALKDAGVKLDYVIEIAVPDEDIVKRMSGRWVHLASGRSYNTQSNPPKVAGQDDITGEALIQRDDDREETVRHRLGIYQQQTRPLVDYYSSWAAQDPANAPKYRKISGVGSVEEIKARAAAALQS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSC9_SCHPO
Sequence: MSQVIQGAVEEPVYSNKSLTNENDSFLSLIESFSQERGVPIDINPKIGRKPILLYELYKKVIKRGGYDAVSATEDGWTNIAEEFNQSDPARSAGILQNVYFKYLISWEIHDHWHLLLPPPSTLELSENRQNVLERVKVFNSCSPPKPTNPITIIDNDKTHSFKKFYKSLVKEDEENGIEKKINEAMNSSASQPLPNSTNFASTTFPSVPFHPLPVDSGLQKYIDRNSNLTPPALGAGVPGPPLLVRVALALKSQQDKEVDWAIGHLIKISFERHQEFKLERLPSLAECLVYSLGFQVTKAKQVSDLTDISLCMDRAIGIALVLRNSVLSVENAKHVAQTKLVISVLEASIRCAKTFNNLEFLHYCLDISEMISSYLHVEDEKNVFYLALCEFLNSSDYSILIATLRTLARLALNDRNNRLLQDLKSNVIANIIALVETDNEEIVAAALDFLYQYTTYRTNTSNLLASQEAWMLVDQLIRLMMYQAQERFMTVTIENSESNPAVKHEATSSISLPMEELQQLVAMREPERSVKWMRCCFEPSSDDYVLQTDIWQLYCSDMERAQGPNVMGISPADFIKVSSHAFYNARAMTVSTPQLPVEYVINGIKRRKFPTSVNGMRYQPCRWCLDSGKECGELLLGTPLLHSHLQEMHIFPQILETGKCRWSDCKYEIQRLTPASELSHYQLLSHIVTHLHDDSLETLVEGRKLSPSREFRIPLLLTAVDDQGDATGIALTATLVLRNLVRSKQGKMLFSAIESRVLEVSSLNPAVAPYVSEMLLGQI
What is the function of this protein?
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  Controls particularly membrane and organelle development genes.
What are the official names of this protein?
Chromatin structure-remodeling complex subunit rsc9, RSC complex subunit rsc9, Remodel the structure of chromatin complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the RSC9 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EASF_TRIVH
Sequence: MGSINPPQILDIRRSKFEESIPKQVEAGLLSSPKTLPALLFYSTEGIQHWNRYSHASDFYPRHEEIQILKDKATDMAASIADGSVVVDLGSASLDKVIHLLEALEAAQKKVTYYALDLSFSELTSTLQAIPTDQFVHVQFSALHGTFDDGLQWLKETLVIRDQPHCLLLFGLTIGNFSRPNAAKFLHNIASHALVESPSQSSILLTLDSCKVPTKVIRAYTAEGVVPFALESLKYGNTLFQQDAGENVFDPEDWYFLSEWNYVLGRHEASLVPRSKDIKLGRPLDKIVVGKHEKVRFGCSYKYDSEERKELFGTAGLRDVKSWSKEGCDVAFYQLKCCPN
What is the function of this protein?
4-dimethylallyltryptophan N-methyltransferase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid (PubMed:22403186).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:22403186).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (PubMed:22403186).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:22403186).  Chanoclavine-I aldehyde is the precursor of ergoamides and ergopeptines in Clavicipitaceae, and clavine-type alcaloids such as fumiclavine in Trichocomaceae (PubMed:22403186).  However, the metabolites downstream of chanoclavine-I aldehyde in Arthrodermataceae have not been identified yet (PubMed:22403186).
What are the official names of this protein?
4-dimethylallyltryptophan N-methyltransferase easF, 4-dimethylallyltryptophan methyltransferase, Ergot alkaloid synthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: TVP18_KLULA
Sequence: MVSVGFLKSMFNVSGMVADLKSSNFSIYGQWISYLNIIFCLAFGIANIFHFSAVIVFSIIAIVQGLIILFIEVPFLLKICPLSDNFIGFVSKFDTNLRRALFYLVMCAIQWCSIIVQSTSLIVVAVGLSITATVYALGAAAGQEFKNSAILSDRGRVAASVTNEAVVRDML
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP18.
What is the protein family that this protein belongs to?
Belongs to the TVP18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RIMK1_SHEFN
Sequence: MHIAIMSRNKNLYSTSRLKEAAEARGHVIKIVDPLKCYMNINMNAPSIHVRGEELPKFDAVIPRIGASVTFYGTAVLRQFEMMGTHPLNESVAITRSRDKLRSLQLLSRKNIGLPVTGFASKPADIPDLLDMVGGAPCVIKLLEGTQGIGVVLAETRKAAESVIEAFMGLKANIMVQEYIAEAGGADIRCFVIGDKVIAAMKRQALPGEFRSNLHRGGSASIVKLTPEERSTALRAAKTMGLNVAGVDILRSKHGPLVMEVNSSPGLEGIEKATGIDVAEKIIQFIEKNVKSTSSKTKGVG
What are the official names of this protein?
Probable alpha-L-glutamate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: PR20E_HUMAN
Sequence: MEEPRPSKRLRSMAPNQASGGPPPEPGCCVADPEGSVEADGPAQPAQPAKPIAYVKPFRRQPPARPESPPPAERGRRRGGSRRPGRGRGRRAGPRGDAGQRQGAEGLMAPDVHIQLDHHGEPGHQGEPEITETAAFSLSETGPPPGTVQEGPGPDVAQPELGFQEPPAAPGPQAVDWQPVLTLYPCIGFRALGDSAVLQVIQTPQGTYVQGVPVFLTDIAY
What are the official names of this protein?
Proline-rich protein 20E.
What is the protein family that this protein belongs to?
Belongs to the PRR20 family.
Protein: DAPE_NITOC
Sequence: MSATLELAKRLIACASITPRDAGCQGLLAQRLLALGFQGEQMNFGEVDNIWLRRGQKPPLFVFAGHTDVVPPGPPDKWLTDPFTPEVRNGLLYGRGAADMKGSLAAMVTACEHFINVHSDHAGSIAFLLTSDEEGPAINGTIKVVETLQARGEKIDYCLVGEPTSQKQVGDMIKNGRRGSLGGRLIVRGIQGHVAYPHLADNPIHSLAPALAVLCAQTWDQGNKDFPPTTFQISNIQGGTGATNVIPGEVEILFNFRYSTEVTHQQLQQQMEEILSQQRLNYELEWTLSGKPFLTAPGSLMTAVSQAVRGITGIDAEFSTTGGTSDGRFIAPTGAQVVELGPVNATIHKVNECVAVADLEILSRIYSRILEILLTE
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CYB_TRASA
Sequence: MAPNIRKSHPLLKMINNSLIDLPTPSNISAWWNFGSLLAMCLATQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIFLHIGRGLYYGSYLYKETWNTGVVLLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGITITHLMFLHESGSNNPLGISSNSDKIPFHPYYSLKDILGLTLMLTPLLTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILLLIPFLHKSKQRTMTFRPLSQTLFWLLVANLLVLTWVGSQPVEHPFIIIGQMASFSYFTILLILFPMTSTLENKMLNH
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FTHS_CORDI
Sequence: MPTDVEIAQAHTLEPITDIANRAGVPSDALIPYGFTKAKIDINRIASENTGKLVLVTGISPTPAGEGKSTVLIGLSDAMRLRGHNSIVAIREPSLGPVMGIKGGAAGGGYSQIVPMEDINLHFTGDFHAITAANNTLAAMIDNHIHQGNTLGIDVRRITWQRCLDVNDRCLRKVVTGLGGKAHGVPTETGFTITAASEIMAILCLALDLTDLEARLARIVVGQTFSSEPVTVGQLNAQGALAALLRDAVNPNLVQTLGGTPALCHGGPFANIAHGCNSLIATKTALSLGDVVLTEAGFGSDLGAEKFFDIKSRVGDLNVAATVVVATVRSLKYNAGVPKDELTTENLEALASGVVNLERHVENIRAFGIEPIVALNKFASDTDAEINQLKAWAETMSVQLIPVEVWAHGGQGALELADAVAVSMQNQTSHHLYDPELGIEASLLTIAQKIYGAADVELSKQARQDLAYLQENGWDRLPVCISKTQYSFSDDPSQLGRPEGHTLHVRNLLPRIGAGFIVALTGDVMTMPGLPKKPAAENIGVENGEIKGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RECR_DESOH
Sequence: MLPYPPSIRNAISHLSRLPGIGQKTAERLAMHLLHVPDRAVHELARSLVDLKKNTRMCSVCFTLSDTPVCAICGDPDRNASLLCVVEGPTEVMAIEKTAAFKGVYHVLHGVLSPMDGIGPDDIRIRELVDRVKKGIVKEIVLATDTRVEGEATAAYLVEVLKPFPVTVTRIASGMPAGGEVRYSDPVTLKNAMEKRYAL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.