PharMolix/UniProtQA huggingface dataset:
Protein: MSRA_MYCPU
Sequence: MQKEIFIAGGCFWGVERYFQKVKGVLDTKACYINGGFEGVKYKEVCEGSSHVEAVRVIYDNSKITEEDLWKLYLRIINPYSLNKQGNDRGVQYRIGLYSYDKDLLKKFSDLNEAFMKSEGKKNYIEIQKVEDVTLAEEYHQNYLLKNVNGYCHINLDDIPEEYQKQ
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: UXAC_ECOLI
Sequence: MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: HIS4_SPHAL
Sequence: MAALTIFPAIDLKAGQVVRLAEGDMDRATVYGDDPAAQARRFADAGATHLHVVDLDGAFAGASVNGAAVESIIAAFPGQVQVGGGIRDRAGVDRWLALGVARVIIGTAALKDPEFVKSAARDLPGRIVVGVDARDGMVATEGWADVSDVRVEDLARRFEDAGVAALLFTDVGRDGLLKGCNVAATVALAGVVDIPVIASGGVAGIEDIHALRPHVADGIEGVITGRALYDGRLDLAEAIAAGAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCDX_ECOL6
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIAEFADL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: RPB9_ASFP4
Sequence: MKICKACSSCMVRTYVDGNIIFRCSCGESVQGDSQNLLVSSKVYHTGEMEDKYKIFIKNAPFDPTNCQIKKDCPNCHLDYLTQICIGSQKIIILVCRCGYTSNRG
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB9 homolog, RPB9 homolog.
What is the protein family that this protein belongs to?
Belongs to the Asfivirus DNA-directed RNA polymerase RPB9 homolog family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: ADH2_CERCA
Sequence: MGLSGKNVIFVGGLGFIGYEACKQLMAKNMASFFVFDVLDKPENIKALQALNPKTKVYYTKFDITSKQSIKSALADVVAKVKYIDALINGAGILTDPNVELTMNINLIGLINTTLEGLPLMDKNKQGRGGVIVNIASVLGLEPCPPAAVYCASKFGVMGFSRSIGDPYYYNITGVAVVTFCPGLTETPLKNNIGSKYTFEYSKKISEELNSTKTQKPEVCGAHLAQVVESHENGGIYISNQGTLAKVTPTVYWQPTYH
What are the official names of this protein?
Alcohol dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: IF4E3_ORYSJ
Sequence: MEPAAEKREAEQEELQQQHDEPAVPSADDDEAEAEENERRNRELKAGFHPLRRRFVLWYTRRTPGARSQSYEDNIKKIVDFSTVESFWVCYCHLTRPVSLPSPTDLHLFKEGIRPLWEDPANRSGGKWIIRFKKTVSGRFWEDLVLVLVGDQLDYSDDVCGVVLSVRFNEDILSVWNRNASDHQAVMTLRDSIKRHLKLPHSYLMEYKPHDASLRDNSSYRNTWLRG
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
What are the official names of this protein?
Eukaryotic translation initiation factor NCBP, Novel cap-binding protein, nCBP, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
Protein: Y1546_STRP1
Sequence: MADKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIVTLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLEDGEYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN
What are the official names of this protein?
Uncharacterized acetyltransferase SPy_1546/M5005_Spy1274.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: MEPA_ESCF3
Sequence: MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKKRWTSAQLLRPQALDLVSRDGKHVVPTLWKPEIFSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ACP_BACFN
Sequence: MSEIASRVKAIIVDKLGVEESEVTETASFTNDLGADSLDTVELIMEFEKEFGISIPDDQAEKIGTVQDAVAYIEEHAK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTER_PIG
Sequence: MSANSMSDPRSPNKVLRYKPPPSECNPALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSEDTKQMMSSFMLSISAVVMSYLQNPQPMTPPW
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity).  Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein.  Within the PAT subcomplex, WDR83OS/Asterix binds to and redirects the substrate to a location behind the SEC61 complex (By similarity).
What are the official names of this protein?
PAT complex subunit Asterix, Protein WDR83OS homolog, Protein associated with the ER translocon of 10kDa, PAT-10, PAT10.
What is the protein family that this protein belongs to?
Belongs to the Asterix family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DEF3_RAPSA
Sequence: MAKFASIVALLFAALVVFAAFEAPTVVEAKLCERSSGTWSGVCGNNNACKNQCIRLEGAQHGSCNYVFPAHKCICYFPC
What is the function of this protein?
Possesses antifungal activity sensitive to inorganic cations.
What are the official names of this protein?
Defensin-like protein 3, Cysteine-rich antifungal protein 3, AFP3.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: SRSF1_XENTR
Sequence: MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGAGGRGGGGGGGGGGGGGGGGGGGGGGGGGGGAPRGRYGPPSRRSEYRVVVSGLPPSGSWQDLKDHMREAGDVCYADVFRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT
What is the function of this protein?
May play a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing.
What are the official names of this protein?
Serine/arginine-rich splicing factor 1, Splicing factor, arginine/serine-rich 1.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus speckle. Note=In nuclear speckles. Shuttles between the nucleus and the cytoplasm.
Protein: SYFA_SULAC
Sequence: MLSENEIKILSYLKLKKKANAEEISKELGLPLSSIFSLAKLLEEKGYVKIGERKIIRFELTEEGKKRLKEGFPEEILLKELNGQPSLIEDLKNKMGKDLEIAISWARKKNLVKIDQNRVIPNTSNYTFSTEKEALLKPESADEKVLQELLSRKLITRKEESKLEITLLKEEFEEQNYITQLTSELLRSKDWKKYKIREYNVEALPPYFPLAKKHFFRDFIEKLKDVMKELGFTEVNAGYIEMELYNFDLLFQAQDHPAREIHDSFRVDGLGKIDDERLLKEIKEMHEKGWKYSWDPQIAKRLVLRSQTTAVTARILSSRPSVPFKGFSLGKVFRPDSIDATHLIEFHQLDGVIIQKEFSFTDLLGILREIFYKIGIKEIKFKPGYFPFTEPSVEVYGKIEGLGWVEMSGAGLLRPEILKAMDIDANAGAWGIGIDRLAMLLFGLKDIRLLYANDIDFLRKMKVRL
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1501_MYCTU
Sequence: MIPVKVENNTSLDQVQDALNCVGYAVVEDVLDEASLAATRDRMYRVQERILTEIGKERLARAGELGVLRLMMKYDPHFFTFLEIPEVLSIVDRVLSETAILHLQNGFILPSFPPFSTPDVFQNAFHQDFPRVLSGYIASVNIMFAIDPFTRDTGATLVVPGSHQRIEKPDHTYLARNAVPVQCAAGSLFVFDSTLWHAAGRNTSGKDRLAINHQFTRSFFKQQIDYVRALGDAVVLEQPARTQQLLGWYSRVVTNLDEYYQPPDKRLYRKGQG
What are the official names of this protein?
Uncharacterized protein Rv1501.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: YBEY_BRUC2
Sequence: MSDNAIHIDIMIEAGNWPDEASLESLVSKSVAAAWNNLGLKSATSELSVVFTDDASIQLLNGEWRGKDKPTNVLSFPAFPVKAGSQPGPMLGDIVIARETVEREAKEEGKPIENHLSHLVVHGFLHLLGYDHETDEEAEVMEAREREILHALAIPDPYAVSDEDINND
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_NATPD
Sequence: MSLRVTFLGTSGAVPTTRRNTSAVFLRREGDRMLFDCGEGTQRQMMRFGTGFAVSKAFITHLHGDHILGLPGLLQTMDFNDREEPLSVYVPSGKQAELRDLIDTAAGAPSFPVHVNGVSDGQVVVDADDYEIRAFETDHDARSLGYALIEASRKGRFDRERAEELGVPVGPKFQQLHAGEAVELEDGTVVEPEQVVGDPRPGRRVVYTGDTRPTDRTVTVAENADLLIHDATFATDNADRAARTAHSTAAEAADIASRADARRLALVHISSRYAGDPSPIEREADDAFGGEAFVPEDGDTVDIPFPDE
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: PFKA_BACAN
Sequence: MKRIGVLTSGGDSPGMNAAIRAVVRKAIFHDIEVYGIYHGYAGLISGHIEKLELGSVGDIIHRGGTKLYTARCPEFKDPEVRLKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEQGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHERTYVIEVMGRHAGDIALWAGLADGAETILIPEEEYDMEDVIARLKRGSERGKKHSIIVVAEGVGSAIDIGKHIEEATNFDTRVTVLGHVQRGGSPSAQDRVLASRLGARAVELLIAGKGGRCVGIQDNKLVDHDIIEALAQKHTIDKDMYQLSKELSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR3_PANGI
Sequence: MGQKINPLGFRLGTTQGHHSLWFAQPKNYSEGLQEDQKIRDFIKNYVQKNMKISSSVEGIARIEIQKRIDLIQVIIYMGFPKLLIESRPRGIEELQMNLQKEFKSVNQKLNIAITRIAKPYGSPNILAEFIAGQLKNRVSFRKAMKKAIELTEQADTKGIQVQIAGRIDGKEIARVEWIREGRVPLQTIRAKIDYCSYTVRTIYGVLGIKIWIFIDGEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS9_YERE8
Sequence: MAENQYYGTGRRKSSAARVFLKPGSGKIVINQRSLEVYFGRETARMVVNQPLELVDMVTKFDMYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAGFVTRDAREVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: THIC_META3
Sequence: MTQMTDAKNNIITKEMEFVAKEENIAVEKIRKWVAKGFVVIPKNIHRNTKPVGIGDNLKTKVNVNLGTSTDCIDIDMEIRKAIISEEYGADAIMDLSTGGELPEIRKQILKNTTLPVGTVPMYEIGIESKNKYGRVIDFDEDIIFNTIERQAKEGVDFMTLHCGITKHTIDTLNNDDRIMGVVSRGGAYITAYIMHHQKENPLYSQFDYLLEMLKEHDVTLSLGDGMRPGCLCDHTDRPQIQELIVLGELVDRCREAGVQVMVEGPGHVPLNNVETNMKIQKTLCKNAPFYVLGPLPTDLAMGYDHITSAIGGALAAYSGANFLCYVTPAEHVRLMNEDDVREGLIASKIAAQVADVAKGNKQAWAKEKEMAIARKNHDWEKQFELSIDSDKPKKMREELPPKEEDACSVCGEYCALLMVEEAGKR
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: APT_PSEP1
Sequence: MHSDAFDLKALIRPVVDFPKPGVIFRDITPLFQSPRGLRYVADQFIERYVEAEFSHIGAMDARGFLIGSIIAHQLNKPLILFRKQGKLPADVLSEGYQTEYGEAFLEVHADSLCEGDSVLIFDDLIATGGTLLAAANLVRRTGAQVFEAAAIIDLPELDGSRRLQAAGVPTFCLTEFSLSEY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANR16_RAT
Sequence: MAPPGDPRRLCRLVQEGQLRALREELEVAGGCWDPEMFRGSQGPAGDTLLHFASRHGRQDILAYLVEAWSMDIEAANRDYKRPLHEAASMGHRDCVRYLLGRGAVVDSLKKADWTPLMMACTRKNLEVIQDLVEHGANPLLKNKDGWNSFHIASREGDPVILRYLLTVCPDVWKTESKIRRTPLHTAAMHGCFEAVQELLERCHYEPDCRDNCGVTPFMDAIQCGHVSIAKLLLENHEACSSATDSLGAQALHRAAVTGQDEAIRFLVCGLGIDVDVRAKSSQLTALLYAAKEGQTSTVQTLLSLGADINSTDERNRSALHLACAGQHAACARFLRQSGLKDSADLTGALAQQLTRGVAILQDFDPGVKS
What is the function of this protein?
Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity.  Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 16.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SRAC1_MACFA
Sequence: MSLAAYCVICCRRVGTSTSPPKSGTRWRDIRNIIKFTGSLILGGSLFLTYEVLALKKAVTLDTQVVEREKMKSYIYVHTVSLDKGENHGIAWQARKELHKAVRKVLATSAKILRNPFADPFSTVDIEDHECAVWLLLRKSKSDDKTTRLEAVQEMSEAHHWHDYQYRLIAQACDPKTLIGLARSKESDLRFFLLPPPLPSLKEDSSTEEELRQLLASLPQTELDECIQYFTSLALSESSQSLAAQKGGLWCFGGNGLPYAESFGEVPSATVEMFCLEAIVKHSEISTHCDKIEANGGLQLLQRLYQLHKDCPKVQRNIMRIIGNMALNEHLHSSIVRSGWVSIMAEAMKSDRIMEASHAARILANLDRETVQEKYQDGVYVLHPQYRTSRPIKADVLFIHGLMGAAFKTWRQQDSEQAVIEKPMEEEDRYTTCWPKTWLAKDCPALRIISVEYDTTLSDWRARCPMERRSLLSISSGIGEVLESPLHSEATNFLGSSELLVLGIGRWFGYHIAWEVFSSKRCCWKPLRSQK
What is the function of this protein?
Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking.  May catalyze the remodeling of phosphatidylglycerol and be involved in the transacylation-acylation reaction to produce phosphatidylglycerol-36:1.  May be involved in bis(monoacylglycerol)phosphate biosynthetic pathway (By similarity).
What are the official names of this protein?
Protein SERAC1, Serine active site-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SERAC1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Endoplasmic reticulum. Mitochondrion. Note=Localizes at the endoplasmic reticulum and at the endoplasmic reticulum-mitochondria interface.
Protein: GLMU_RHIEC
Sequence: MERTCLAVILAAGDSTRMKSSKSKVLHPVAGRPMIAHVVEAVASAGISSVALVVGRDAGEVAKAASIDGVGIEAYLQQQRLGTGHAVLAAREAIAKGYDDILVTYGDVPLQTNGPLKAARQGLAEGSDVVVIGFHTDRPTGYGRLLVKDGELIAIREEKDASDAERAVTWCNSGLMAINGRKALDLLSRIGNANAKGEFYLTDLVEIARSLGGRVTAVDAPEIEMTGCNNRAELAVIERFWQERRRREMMLAGVTMIAPETVFLSYDTVIGQDALIEPNVVFGPGAVIDSGAVIHAFSHIEGAHVSEGATVGPFARLRPGADLAMGSKVGNFCEVKNGRIGVGAKVNHLTYIGDAVVGAGSNIGAGTITCNYDGVNKSETVIGENAFIGSNSSLVAPVTIGDGAYIASGSVITVDVPADALALGRARQEIKPGRATLLRQRALAIKAAKKAEA
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_HAEIE
Sequence: MRVSDFNFDLPDELIARYPKTDRVSCRLLQLNGENGEIFHRTFSDVLDLIDEGDLLIFNNTRVIPARMFGRKASGGKIEVLVERMLDEHRFLAHIRSSKSPKEGAELFLGEDKLGENNGIKAVMKARHSSLFEVELSDKSTALLDVLQTIGHMPLPPYIDRPDEEADKECYQTVYSKVPGAVAAPTAGLHFDENLLEKLKAKGVNFEFVTLHVGAGTFQPVRVENIEDHVMHAEYVEVSQEVCNAIIATKKAGKRVIAVGTTSVRSIESAALSAEEFGNPDLIEPYFSDTSIFIYPGKKFRVVDCLITNFHLPESTLIMLVSAFAGYKNTMNAYKQAVQEKYRFFSYGDAMFINKNSNVRELE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFB_ECOLU
Sequence: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMRDKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKIGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVIAVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HFQ_VEREI
Sequence: MSNKGQLLQEPFLNTLRREHVPVSIYLVNGIKLQGQIESFDQYVVLLRNTVTQMVFKHAISTIVPGRAVHFSTAEPADANSNNG
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RL35_BIFLO
Sequence: MPKMKTNSAASKRAKITGTGKVKHVGSAMRHNLEHKSARKRRELSADDVLRGGQAKKLHQLLQK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: Y2611_SYNJA
Sequence: MILCIGDVLSLAELQQILSLIADAEFVDGALTAGWNARLVKNNRQMPKGSLQQRKIEEIILAALERNLLFQMAARPKLIHSILISCYEAGMSYGTHTDDALMLDRHQLMRTDISFTLFLSAPEDYDGGELKIESSEGEQAYKLPAGALILYPASTLHRVEPVTRGIRYAAVSWVQSLIRDPQEREILFDLQTVRQQMFQESGKTRHFDLISKVYANLLRKWAEL
What are the official names of this protein?
PKHD-type hydroxylase CYA_2611.
Protein: Y2784_BRUAB
Sequence: MLIRKWKAGLLAGLSILALASSADAGEVRMTVAEYSAKTGPYFEEVKKAFEAENPGITLNFEVVPWDVLLQKLTTDISAGTNADLSIIGTRWLIDFVQQGIAEPLDGYMNDEFKGRFIETFLSPSVLDGKTYGLPIAASARAMYYNKDLFEKAGIKNPPANWDELKADAAKIKALGGENYGFGLQGKEIETDVYYYYAMWSYGTEILNKDGTSGLSTPGALEAAKLYKSMIDDGLTQPGVTSYAREDVQNLFKQGKVGMMITAPFLSNQIKEEAPNLKYGVAAIPAGPTGARGTYGVTDSVIMFQNSKNKEEAWKVLDFLFQKDWRAKFTQNEGFLPVNKEEAKMDYYVNNADLAAFTALLPDARFAPVIPGWEEIADITSNAMQSIYLGKGEPDAVLKDAAAKADAILKK
What is the function of this protein?
Probably part of an ABC transporter complex.
What are the official names of this protein?
Putative binding protein BruAb2_0484.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CHIPS_STAAN
Sequence: MKKKLATTVLALSFLTAGISTHHHSAKAFTFEPFPTNEEIESNKKMLEKEKAYKESFKNSGLPTTLGKLDERLRNYLEKGTKNTAQFEKMVILTENKGYYTVYLNTPLAEDRKNVELLGKMYKTYFFKKGESKSSYVINGPGKTNEYAY
What is the function of this protein?
Involved in countering the first line of host defense mechanisms.  Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP).  Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses.  Prevents phagocytosis of the bacterium (By similarity).
What are the official names of this protein?
Chemotaxis inhibitory protein, CHIPS.
What is the protein family that this protein belongs to?
Belongs to the CHIPS/FLIPr family.
What are the subcellular locations of this protein?
Secreted.