PharMolix/UniProtQA huggingface dataset:
Protein: TRPD_ALKMQ
Sequence: MMQQAIDKVIRRQDLAETEMMAVMQGIMEGKVTDSQIGGFLTALRMKGETVEEITASAKVMRSKALVVEVNQPHSIDTCGTGGDQANTFNISTAVAFVAAAAGVTVVKHGNRSVSSQCGSADVLEKLGVNIDLTPKQVETCVEQVNMGFMFAPKFHQAMKYAAAARRELGVRTIFNILGPLTNPAKVKGQVLGVFDESLTEVMAQVLKELGVERGMVVHGLDGLDEITTTTKTKVSELKNGMISNYVIDPRQFDIPLTDKEDLAGGDAEKNASIILNIVKGETGGKRNMVLINAGAAIYVGNAANSLQEGIDRAAEVIDMGLALDKLNQLIKLSQELKV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: PIMT_HELPY
Sequence: MNSIKNHLMCEEINKRFNLHPKVREAMESIEREVFVPAPFKHFAYTLNALSMQAQQYISSPLTVAKMTQYLEIDHVDSVLEIGCGSGYQAAVLSQIFRRVFSIERIESLYIEARLRLKTLGLDNVHVKFADGNKGWEQYAPYDRILFSACAKNIPQALIDQLEEGGILVAPIQENNEQVIKRFVKQNNALRVQKVLEKCLFVPVVDGVQ
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins (By similarity).
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_KLEPN
Sequence: MSTKAIYPGTFDPITNGHIDIVTRAASMFDKVVLAIAASPSKKPMFSLDERIALAEQATAHLVNVEVIGFSDLMANFARAQQANILIRGLRAVADFEYEMQLAHMNRHLMPTLESVFLMPCKEWSFISSSLVKEVARHQGDVSHFLPANVHQALLNKLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASY_NEUCR
Sequence: MASVETLLQGVTISGPIEEHQRKILTPQALSFVALLHRSFNQTRKNLLERRQLRQAEIDRGVLPDFLPETKHIRENPTWKGAPPAPGLVDRRVEITGPTDRKMVVNALNSDVYTYMADFEDSSAPTWANMVNGQVNLYDAIRRQIDFKQGPKEYKLRTDRTLPTLIVRPRGWHLEEKHVTIDGEPVSGSLFDFGLYFFHNAKELVQRGFGPYFYLPKMESHLEARLWNDAFNLAQDYVGIPRGTIRGTVLIETILAAFEMDEIIYELREHSSGLNCGRWDYIFSTIKKFRNHSSFVLPDRSCVTMTVPFMDAYVKLLIQTCHKRGVHAMGGMAAQIPIKDDKAANDKAMEGVRADKLREARAGHDGTWVAHPALASIALEVFNKHMPTPNQLFNRREDVKIGQQDLLNMNVPGSITEEGIRKNLNIGLGYMEAWIRGVGCVPINYLMEDAATAEVSRSQLWQWVKHGVTTAEGKRVDKSYALKLLKEQTDELASKAPQGNKFNLAAQYFATQVTGEDYADFLTSLLYNEITSAGNSLPASKL
What are the official names of this protein?
Malate synthase, glyoxysomal, Acetate utilization protein 9.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: ATPE_PELHO
Sequence: MTLNLCVLTPNRILWDSEVKEIILPTNSGQIGVLPNHASIVTTIDIGVLRIRHFNDQWFTIALMGGFTRIRNNEITILATAAEKGSDIDPQEAQQTLQIAEDSLRKAEDKRQRIEAKLAIKRASTRVKAINPIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: YO24_BPHC1
Sequence: MERISGMSFDFYLFGLPIHAESISLSITDNSTVVQTRGIPDGWVSGDVAAEGEIELDAKNFSKLSAAAAAAGSYRSLPETDFTFFAQRGGIRDKVETFGNKIILTDVLNIDPKGGAKSMKKLKYFVTSPDFVRINGVSYLSDEDTRDLLG
What are the official names of this protein?
Putative tail tube protein, ORF24.
Protein: AROC_VIBPA
Sequence: MAGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLEITEADLQTDLDRRRPGTSRYTTQRREPDEVKILSGVFEGKTTGTSIGLLIENTDQRSKDYSDIKDKFRPGHADYTYHQKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLKDEFGVEIRAYLSQMGDVSIDKVDWDEIENNAFFCPDADKVEAFDQLIRDLKKEGDSIGAKIQVVATNVPVGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVNQKGSQHRDPLSPQGFGSNHAGGILGGISTGQDIVANIALKPTSSITVPGDTITKEGEPTQLITKGRHDPCVGIRAVPIAEAMLAIVVMDHLLRHRGQNHGVTTETPKI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RUVB_PSEU2
Sequence: MIDADRLITATGGRDRDEQMDRAIRPLSLADYIGQPTVREQMELFIQAARGRSEALDHTLIFGPPGLGKTTLANIIAQEMGVSIKSTSGPVLERPGDLAAILTNLEPNDVLFIDEIHRLSPIVEEVLYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGMLTNPLRDRFGIVQRLEFYNIADLSTIVSRSAGILGLVIEPQGAFEIARRARGTPRIANRLLRRVRDFAEVRGNGQITRQTADKALNLLDVDEHGFDHQDRRLLLTMIEKFDGGPVGVDSLAAAISEERHTIEDVLEPYLIQQGYIMRTPRGRVVTRHAYLHFGLNIPSRMGEIPVPDDFGDEPVDL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RS4E_SULAC
Sequence: MVHITRFEAPWFLKVGKKEYKWIIRSRAGPHKIQESVPLAILLKYYLKAVDTTREAKRIIFDGKVLVDGKVRRDYKYPVGLMDVVEIPSADLRVRIIPDNVRYLTTINISREDAKYKFVRIMNKTTLKSGVLQLNLEDGRNILLKGEELSQYNLPTLTTLKIELPEQKITTAYTIKEGVYAMIIGGRNAGLHGKISKIQLAKYKRIKYSLVTLEGKDGSTFQTNLINVMAIGENEADSNLGVKL
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: KCNN3_HUMAN
Sequence: MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQQQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQHAGTTASSTTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSSTSFPTPYTSSSSC
What is the function of this protein?
Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:31155282, PubMed:20562108).  Activation is followed by membrane hyperpolarization (By similarity).  Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization (By similarity).
What are the official names of this protein?
Small conductance calcium-activated potassium channel protein 3, SK3, SKCa 3, SKCa3, KCa2.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GSM1_VANPO
Sequence: MTKKLPVEKKLSRKPISRACEFCHLKHLQCDTGRPCQNCVKRNIGKGCKDKERKTKKRQLKNNTSNSDLENIPKQVKTDIIPGPIRMTPTTAIYQQNNDFSIKKIHSLTTILNSTNSFLGTDFVNTGNIDDPKNEINNPPSTLSISTNGSNPDSTFDSIWAGDEYKKLNDIIGLGRASGLSLSHPNTETEKGIVHVNSISKINSRPFISLSIDSTGGSIDEYNLRYSIPSDSTKFKQLKIDTNESFLSPYMFRKAIKTPKEFHEKRSTILPHNYRIGYRYLLKTLHNMFINETTLDAETLSIRKQQVSYIVKSILVKYTENFISISSNMVEEDLLLQELTLQRTLLEFESMSRLVPATPIAIWRRTGEICYISSEFTSLTGFTKKEVLNKRSYIFEYMDHESVIHYFETIYNKLSFNISSNAAKFSSSNNFLFTKCNLLLNNGSFLKCVCCWTVTRDTLKIPVLFTGHFMPIFDVQ
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.
What are the official names of this protein?
Glucose starvation modulator protein 1.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YABA_STRPJ
Sequence: MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLENSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELLYRE
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: OXLA8_DEIAC
Sequence: ADDRNPLEEFRENNYEEFL
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme.  Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation.  Its effect on platelets is controversial, since it either induces aggregation or inhibits agonist-induced aggregation.  These different effects are probably due to different experimental conditions (By similarity).  Induces apoptosis in HeLa cervical cancer cells.  Both the caspase-dependent and the mitochondrial pathways seem to be involved in apoptosis (PubMed:17275856).
What are the official names of this protein?
L-amino-acid oxidase ACTX-8, LAAO, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS6_BACVZ
Sequence: MKKYEVMYIIRPNIDEESKKAVIERFNNVLTSNGAEITGTKDWGKRRLAYEINDFRDGFYQILNVQSEAAAVAEFDRLAKISDDIIRHIVVKEEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RS21_STAAS
Sequence: MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: NDVA_RHILO
Sequence: MSLLQIYWRALGYLAADKRRVALICGANVALAAIAILEPIMFGRVIDAISEHGSVFSTLAVWAGLGAFNVIAFVLVARGADRFAHARRSEVLCQSFERVITMPLAWHHQRGTSNALHTLLRAVETLFSLWLEFMRQHLSTAVALVLLVPTALSMDVRMSMVLLGLGVLYVGIGRLVMKRTKAGQAAVERHYHKVFAHVTDSVSNVAVLQSYNRLGHEAETLRRYVKNLLDAQNPVLDWWAIANALNRLSSTISMMVVLLIGAYLVTHGQLRVGDVIAFTGFATLLISRLDQMSAFANQISEARAKLEEFYKLEDSAADAAEPDGLRDLTNVTGHVRFEDVGFEFANSGQGVSGVSFEVQAGQTVAIVGPTGAGKTTLINLLQRVFSPSTGRILIDGIDTRTVTRKSLRHSIATVFQDAGLLNRSIEDNIRVGRADASNVEIHAAAVAAAAQDFILAKSGGYDTVVGERGGQLSGGERQRIAIARAVLKDAPILVLDEATSALDVETEDRVKEAIDELRRDRTTFIIAHRLTTVRDADLVVFMDKGRVVEMGGFAELSLRNGRFASLLRAGGLLNDEEVRRLSRSVQGEAA
What is the function of this protein?
Involved in beta-(1-->2)glucan export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Beta-(1-->2)glucan export ATP-binding/permease protein NdvA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Beta-(1-->2)glucan exporter (TC 3.A.1.108.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLIE_BUCAI
Sequence: MFIENINHQNINTKFNLLDAQKKDSENFIDYIKIALGEISKNQNHAKIDSEKFILNQSGISLNDVMINLEKSSISMQLAVQIRNKIVSAYQEIMSQQI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: DPPB_PSEAB
Sequence: MLSFIARRLGLLIPTFFGVTLLTFALIRLIPGDPVEVMMGERRVDPQMHAEALHRLGLDKPLYQQYLDYVGNLAQGNLGESLTTREGVWHEFLTLFPATLELSLAAMLFAGTFGLLAGVIAALKRGSLFDHGVMTVSLAGYSMPIFWWGLILIMLFSVSLGWTPVSGRLDLLYDIEPKTGFMLIDTLLSDEQGSFLDAVRHLILPAIVLGTIPLAVIARMTRSAMLEVLREDYVRTARAKGLSPARVVFVHALRNALIPVLTVFGLQVGTLLAGAVLTETIFSWPGIGKWLIDAISRRDYPVVQNGILLVATLVILVNFVVDILYGLANPRIRHQR
What is the function of this protein?
Part of the ABC transporter DppABCDF involved in the uptake of various di/tripeptides (PubMed:25338022).  Is also involved in the uptake of phaseolotoxin, a toxic tripeptide inhibiting the enzyme ornithine carbamoyltransferase (PubMed:25338022).  Responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Di/tripeptide transport system permease protein DppB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDHI_RAIAR
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLENDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PME35_ARATH
Sequence: MATTSFSLPNHKFGIKLMLFLVLNLLSLQTSVFAHSSNSKFTKISRHPNSDSSSRTKPSTSSNKGFLSSVQLSLDHALFARSLAFNLTLSHRTSQTLMLDPVNDCLELLDDTLDMLYRIVVIKRKDHVNDDVHTWLSAALTNQETCKQSLSEKSSFNKEGIAIDSFARNLTGLLTNSLDMFVSDKQKSSSSSNLTGGRKLLSDHDFPTWVSSSDRKLLEASVEELRPHAVVAADGSGTHMSVAEALASLEKGSGRSVIHLTAGTYKENLNIPSKQKNVMLVGDGKGKTVIVGSRSNRGGWNTYQSATVAAMGDGFIARDITFVNSAGPNSEQAVALRVGSDRSVVYRCSIDGYQDSLYTLSKRQFYRETDITGTVDFIFGNSAVVFQSCNLVSRKGSSDQNYVTAQGRSDPNQNTGISIHNCRITGSTKTYLGRPWKQYSRTVVMQSFIDGSIHPSGWSPWSSNFALKTLYYGEFGNSGPGSSVSGRVSWAGYHPALTLTEAQGFTVSGFIDGNSWLPSTGVVFDSGLL
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Probable pectinesterase/pectinesterase inhibitor 35.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ARGR_SALHS
Sequence: MRSSAKQEELVRAFKALLKEEKFSSQGEIVLALQDQGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPASGFSVRDLYEAILELFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_SORC5
Sequence: MSGVVKRATRVAERLREDLSNLLRDLRDPRIAGVLVSRVEITDDLQSAKVHVRHEFGAEDAAARRALLKGLEAASGRLRRDVARTMGLRVVPTLRFFYDEGPDAERRIEELLREIKDGSSGERS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INT11_PONAB
Sequence: MPEIRVTPLGAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVAVHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPIYFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRNMFEFKHIKAFDRAFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQVLEVKMQVEYMSFSAHADAKGIMQLVGQAEPESVLLVHGEAKKMEFLKQKIEQELRVSCYMPANGETVTLPTSPSIPVGISLGLLKREMAQGLLPEAKKPRLLHGTLIMKDSNFRLVSSEQALKELGLAEHQLRFTCRVHLHDTRKEQETALRVYSHLKSILKDHCVQHLPDGSVTVESILIQAAAPSEDPGTKVLLVSWTYQDEELGSFLTSLLKKGLPQAPS
What is the function of this protein?
Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates the snRNAs 3' cleavage.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 11, Int11, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NAGZ_STRM5
Sequence: MLLIGVAGTELTAQERDWLQHDAVAGVVLFKRNFASRQQVTDLSAAIRAAAPRPQLICVDQEGGRVQRFREGYSELPPLQDIGALYATDPQQALALAEQHAWLMASEVRASGLDLSFAPVVDLGRGNRAIGNRAFSEDPQVVAAFTAAYVRGMHAVGMAATLKHFPGHGTVLEDTHVDTAIDPRALDELRAQDLVPFQAGIAAGADAVMMAHVVYPQVAPEPAGYSPRWIQDILRGELGFRGVVFSDDIGMAASHSAGGVPARVHAHLDAGCDVVLVCHPELVDEALHAVQGRSLNTAALLGLLGRGALGWDGLLADARHGDTQSHLLETLGRTV
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSUG_THET2
Sequence: MREPRVALESAVLTHGLPYPLNLEVALALEEAVREEGATPKTIALVRGEVRVGLSPEEMEALAAGGAEKASLWNLAALLAQGRSAGTTVAATVHLAHLHGIPVFATGGIGGVHPEPYDESADLVALSRTPILVVSSGPKAILDLRATLERLETLGVSVVGYRTDRLPAFFSPDSPFPVPARVDTPMEAARVYLRARALGLGGVLLVNPVSQGLPYEQVALWVEEAGRMAAREGVFGKALTPYLLRKLSELSSGETDRVNRRLLLENARLAARVALALAGLE
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: MDMII_MUSDO
Sequence: MNATDAESRKPENKPSSESSSSGSTSGSSDGEVSSKTYFKNNKSKVLSGQREVVLEVVRDLSYTICKEAEEKLVERFPRKDGSNEMLPKEDSINTNHNYTTDSNEHPVELTTKTEECKNTEKTKKKSFVRALSKDKQLSAYRSRSRSTRLSYSGHISRTHSVEKSLSRYKTSVLRNRRTSFGHGRDSSTTKRSVSRDKDNRLRRRIGSSRSHTRSHSRFRRSEKKLPSRSPRRIRSQERRHERRRSMSSDYERIALRRSEPIKRRDKDEFFKNNKKVSGDIKKGKGNDNGTVAELEAKITERQRKSLDILTSRTGGACLTPDKLRMIQAEITDKSSAAYQSIAREALKKYIHGYINKVNVDSVAVITRKLLKDNIVRGRGVLCHSIIQAQATSPTFTHVYAAMVAIINSKFPNIGELLLKRLVIQFKRAFGCNDKTVCLTSSHFIAHLVNQRVAHEILALEILTLLIESPTDDNVEVAITFLKECGMKLTEVSSDRVGGIFELLKNILHQGKLDKRVQYMIKVLFQVRRDGFKDHQSIIESLELVEEYAQFTHLLLLEDVTYPKDILNEFRFDDQYETNEEKYKALSKNILGSHASDSDGSFGSGSNSETALSDCDKGKNEVNDKYTSGDIIDETKPNLIALRRTIYLTLNSCLDYEECAQKLMKMQLKTCQQNEFCQILLDCCAEQRTYEKFYGLLTHRICKMNKSFIEPFKEIFKDICQTTHCLDTNRLRNISKFFAHLLFTDAISWDVLDCIKLTEDEAITSRCIFIKSFFQELVEYMGLYHFNKKLKTEVLAGTLAGLFPKDNPRNIRFSINFFTSIGLGGITNELCQLLKIAPKSAPSSSSSSSLSSELSAPSDDDSSSDSENKKKHKGKNKKMTKKKNPSKKKEKTKKIVGKNKIAAKNKTIKRRTDKDNSSSKDNFLKSESSSNESISLDSLSSELFAPSSYSSSESSNDSESKEKHKGKNKKMTKKKNPSNKREKTKKKLSKNKKAPNKNTKKRMTEKDISSSESSISESKSLNCSASNQNENEKRKKRVTSKSRTKRVKMFKQCQWVDADNQRDIKRKKRAEYRYEPLVYRKRNEECLKKGAPNCRKDNYGNRQNHEISQRHDSEIKRRREERKKRHHEKNHSREYKRSKLGLCQREYFLYMCCQFYYPCTFQCLCQNCHFTFYS
What is the function of this protein?
Male determiner protein (M-factor) that controls male somatic sexual differentiation.  Acts as a dominant factor that regulates the mRNA splicing of transformer (tra) and doublesex (dsx) transcripts and promotes expression of male splice forms of tra and dsx (By similarity).  Probably acts as a component of the spliceosome C complex required for mRNA splicing factor and exon-junction complex (EJC) assembly (By similarity).  Hinders eIF4AIII from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs (By similarity).
What are the official names of this protein?
Male determiner protein Mdmd(II), Male determiner encoded on chromosome II.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Nucleus speckle.