PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_BORBZ
Sequence: MTNILSAIILGIIQGITEFLPISSSGHLLLFRHFINLKLSIIFDIYLHLATVLVIIIYYRKRILELFLTFIRFSLRKTVKSDLTNLKLILLILIITIVTGVVGTFISKYESMFTLSFVLINFIITGILILMLEFNFLKVDFKGNILLAGIFMGLMQGLGALPGISRSGITIFSASVIGFNRKSAFEISFLSLIPIVFGAILLKHKEFYDIFMVLNFFEINLGALVAFVVGIFSINFFFKMLNNKKLYYFSIYLFALSIIVCYFVRI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXH_PSEPF
Sequence: MTQSLADMRRDYTRDGLTEAQAPAEPFALFHQWFAEAVKTEQAPVEANAMTLATVDADGRPHCRILLLKGLDEQGFTFFTNYESAKGQHLAANPFAAMTFFWPTLERQVRIEGRVVKVTPEESDAYYQVRPLGSRLGAWASPQSRVINGRGELEDLLKATEQRFTDTQPHCPEHWGGYRLLPERVEFWQGRASRLHDRLNYRVQGADWILERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: DJC25_DROME
Sequence: MRTHGLRLVLLALLPTMALGLLEGLYCGKENCYDVLGVTRESSKSEIGKAYRQLARRYHPDLHRGAEAKAAAETQFKLVATAYEILRDEESRTDYDYMLDNPDAYYAHYYRYYRRRVAPKVDVRVVIVVVLTIVSVIQYYSGWQRYDSAIKYFATVPKYRNQALEIARDEIQEKIQKKGKNRMSKNDQRDELERIIRRVIEEKMDVKGGYAKPTLWDVLWVQLIICPYTILSFIVWHAQWFWRYTVMKQPYGREQKLYLIRRHLGMGQHQFEAQEDKLIEEYLHLKLWKRENFVAWKAEQEEEMKKKLAENPRYKAYRRYMKNHGPGRITFED
What are the official names of this protein?
DnaJ homolog subfamily C member 25 homolog.
What is the protein family that this protein belongs to?
Belongs to the DNAJC25 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BP10_BPT4
Sequence: MKQNINIGNVVDDGTGDYLRKGGIKINENFDELYYELGDGDVPYSAGAWKTYNASSGQTLTAEWGKSYAINTSSGRVTINLPKGTVNDYNKVIRARDVFATWNVNPVTLVAASGDTIKGSAVPVEINVRFSDLELVYCAPGRWEYVKNKQIDKITSSDISNVARKEFLVEVQGQTDFLDVFRGTSYNVNNIRVKHRGNELYYGDVFSENSDFGSPGENEGELVPLDGFNIRLRQPCNIGDTVQIETFMDGVSQWRSSYTRRQIRLLDSKLTSKTSLEGSIYVTDLSTMKSIPFSAFGLIPGEPINPNSLEVRFNGILQELAGTVGMPLFHCVGADSDDEVECSVLGGTWEQSHTDYSVETDENGIPEILHFDSVFEHGDIINITWFNNDLGTLLTKDEIIDETDNLYVSQGPGVDISGDVNLTDFDKIGWPNVEAVQSYQRAFNAVSNIFDTIYPIGTIYENAVNPNNPVTYMGFGSWKLFGQGKVLVGWNEDISDPNFALNNNDLDSGGNPSHTAGGTGGSTSVTLENANLPATETDEEVLIVDENGSVIVGGCQYDPDESGPIYTKYREAKASTNSTHTPPTSITNIQPYITVYRWIRIA
What is the function of this protein?
Peripheral baseplate protein that is part of the tail fiber network.  Connects the short tail fibers to the baseplate (PubMed:16554069).  During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure.  At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors.  Involved in the tail assembly.
What are the official names of this protein?
Baseplate wedge protein gp10, Gene product 10, gp10.
What is the protein family that this protein belongs to?
Belongs to the T4likevirus baseplate wedge protein gp10 family.
What are the subcellular locations of this protein?
Virion. Note=Present in 18 copies in the baseplate.
Protein: ACAD9_RAT
Sequence: MSGYVLFSRGATAAAAAARASRVLRVFTERRRTLHTSLQSCSFAKELFLGHIQQKGVFPFPEVSQEELSEINQFVGPLEKFFNEEVDSRKIDQEGKIPADTLAKLKSLGLFGIQVPEEYGGLGLSNTMYARLGEIISMDASITVTLAAHQAIGLKGIILVGNEEQKAKYLPKLSSGEHIAAFCLTEPASGSDAASIQTRATLSEDKKYFVLNGSKVWITNGGLANIFTVFAKTEVVDSDGSIKDKMTAFIVERDFGGITNGKPEDKLGIRGSNTCEVHFENTRVPVENVLGEVGGGFKVAMNILNSGRFSMGSAVAGMLKKLIEQTAEYACTRKQFNRNLSEFGLIQEKFALMAQKAYVMESMAYLTSGMLDQPGFPDCSIEAAMVKVFSSEAAWQCVSEALQILGGSGYMKDYPYERMLRDARILLIFEGTNEILRLFIALTGLQHAGRILTSRIKELKSGNVTTVMETIGRKLRDSLGRTVDLGLSSNIAVVHPSLGDSANKLEENVHYFGRTVETLLLRFGKTIVEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLKNHDHEILLANMFCVEAYFQNLFSLSQLDKYAPENLDEQIKKVSQQILEKRAYICAHPLDRAS
What is the function of this protein?
As part of the MCIA complex, primarily participates in the assembly of the mitochondrial complex I and therefore plays a role in oxidative phosphorylation.  This moonlighting protein has also a dehydrogenase activity toward a broad range of substrates with greater specificity for long-chain unsaturated acyl-CoAs.  However, in vivo, it does not seem to play a primary role in fatty acid oxidation.  In addition, the function in complex I assembly is independent of the dehydrogenase activity of the protein.
What are the official names of this protein?
Complex I assembly factor ACAD9, mitochondrial, Acyl-CoA dehydrogenase family member 9, ACAD-9.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=Essentially associated with membranes.
Protein: SYH_MOOTA
Sequence: MLTSRPRGTEDILPEEVGRWYLLENTAREVSRLYGYREIRTPIFEHTELFNRGVGDTSDIVEKEMYTFIDRGDRSLTLRPEGTAPVVRAFVEHSLEARGLPVKLFYLGPMFRYGRPQAGRLRQFHQFGVEAFGSRDPALDAEVIALAMDFYTRLGLKDLELHLNSVGCPACRPAHREKLKAYLRPRLEELCPTCQGRFERNPLRIFDCKSPACQEIVREAPTVTASLCPDCAGHFHRVQEYLKALGIEFILDEHLVRGLDYYTKTAFEIMVKGIGAQSSIGGGGRYDGLVAALGGKQVPGIGFGLGLERVLLALEIQGQEPPPEGGVDVLVVTAGTGVDLAAFRLLAGLRAAGIRADKDYLERSLKGQMKYANRYPARMAVILGEEELARGRVSVRRLDAGSQEEVPLAAVVDYCRKMKESGW
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_CHRVO
Sequence: MLDRDGYRPNVGIILTNAKNEVFWGKRVREHSWQFPQGGIKPGESPEAAMYRELLEEVGLLPQHVKILGRTRDWLRYEVPTNWVRREWRGSYKGQKQIWFLLRLVGRDSDVCLRATNHPEFDGWRWNDYWAPVDAVIEFKRDVYERALSELARFMRGVESHHAYLARTSTQSEQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: KRIT1_MOUSE
Sequence: MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQSNSEIAQGILDYVVETTKPISPANQGIKGKRVVLMRKFPLDGEKTGREAALFIVPSVVKDNTKYAYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRPSPLERIKTNVINPAYAAELGQVDNSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQYTNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVVEDKERQWVDDFPLHRNACEGDSELLSHLLDKGLSVNQLDNDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLTHPDIDRHITDQQGRSPLNVCEENKQNNWEEAAKLLKDAINKPYEKVRIYRMDGSYRSVELKHGNNTTAQQIMEGMRLSQETQRYFTIWICSENLSLQFKPYHKPLQQVHDWPEILAELTNLDPQRETPQLFLRRDVGLPLEVEKKIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEETLKSIVPITKLKSKAPHWINRILHEYKNLSLSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYCCFTWQLGDAGTCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNGQLMPSERNS
What is the function of this protein?
Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity.  Negative regulator of angiogenesis.  Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells.  Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade.  Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B.  Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization.  Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1.  Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner (By similarity).  Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage.  Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2.  Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels.  May play a role in the regulation of macroautophagy through the down-regulation of the mTOR pathway (PubMed:26417067).
What are the official names of this protein?
Krev interaction trapped protein 1, Krev interaction trapped 1, Cerebral cavernous malformations 1 protein homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell junction. Note=KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions. Association with RAP1 relocalizes KRIT1 from microtubules to cell junction membranes. Translocates from the cytoplasm along microtubules to the cell membrane in an ITGB1BP1-dependent manner (By similarity).
Protein: CYB_SURSU
Sequence: MTNTRKSHPLIKIINESFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYAHANGASLFFICLFMHVGRGMYYGSHAFLETWNIGIVLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGVSSDSDKIPFHPYFTIKDILGLLIALTTLMMLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSIMILAIVPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASILYFSIILILMPIFGTIENQLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CAH1_GORGO
Sequence: MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVTFEDNDNRSVLKGGPLSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHLTHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKILDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase 1, Carbonate dehydratase I, Carbonic anhydrase I, CA-I.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOL_HBVCP
Sequence: MPLSYQHFRKLLLLDDEAGPLEEELPRLADEGLNRRVAEDLNLQLPNVSIPWTHKVGNFTGLYSSTLPVFNPNWQTPSFPDIHLHQDIINKCEQFVGPLTVNEKRRLKLSMPARFYPNSTKYLPLEKGIKPYYPDNVVNHYFQTRHYLHTLWQAGILYKRETTRSASFCGSPYSWEQELQHGAESFHQQSAGIFSRAPVGSSIQSKHQQSRLGLQPQKGLLARGNEGRSWSVRSRVHPTTWRSFGVEPSSSGHTNNFASKSASCLHQSAVRKAAYPTFSTTKRHSSSGHAVELHNISSSSAGSQSKGPVFSCWWLQFRNIEPCSEYCLSHLVSLLDDWGPCTEHGEHHIRIPRTPARVTGGVFLVDKNPHNTAESRLVVDFSQFSRGSTRVPWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSRILDHQHGTMQNLHDSCSRNLFDSLMLLYKTFGRKLHLYSHPIIMGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLYTAVTNFLLSLGIHLNPNKTKRWGYSLHFMGYVIGSWGTLPQEHIVQKIKNCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQAKQAFTFSPTYKAFLSQQYSTLYPVARQRSGLCQVFADATPTGWGLVMGHQRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLIRLLFQPTTGRTSLYAVSPSVPSHLPVRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: THI4_FUSOX
Sequence: MAPPAAVSPPSRSAELATSTKLPVMSKNINTKTVEEMLGQWDDFKFAPIRESQVSRAMTRRYFQDLDNYAESDIVIIGAGSCGLSAAYILGKKRPDLKIAIIEASVSPGGGAWLGGQLFSAMIMRKPADAFLREVGVPYEDEGNYVVVKHAALFTSTIMSKVLQMPNIKLFNATCVEDLITRPSEEGVRIAGVVTNWTLVSMHHDDQSCMDPNTINAPLIISTTGHDGPMGAFCVKRLVSMQRIEKLGGMRGLDMNLAEDAIVKGTREIVPGLIVGGMELSEVDGANRMGPTFGAMALSGLKAAEEALKIFDTRKKQNDL
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Stress-inducible protein sti35, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BIOF_MYCTF
Sequence: MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDYLGLSRHPAVIDGGVQALRIWGAGATGSRLVTGDTKLHQQFEAELAEFVGAAAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDACRLSRARVVVTPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGALLLVDEAHGLGVRGGGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVLGPTPVRAHLIDAARPFIFDTGLAPAAVGAARAALRVLQAEPWRPQAVLNHAGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPTVPAGTSRLRLTARASLNAGELELARRVLTDVLAVARR
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: MAP2_PHANO
Sequence: MAAQVADGVADLKLDDTKSKPTNGTTQNGDAEHEDSDDDNEGEEGAAEGGEGAAKKKKKRKPRKKKKAGAAGASGPKTQTKPPRVPVHEIFLNDSYPEGEIHEYLNENSYRTTSEEKRHLDRMNNDFLTDYRRGAEIHRTVRQWARDWIKPGMSLTEIAEGIEDSVRALTGHQGLEDGDAQIAGMGFPTGLSINHCAAHYTPNAGNKMVVNYEDVMKVDFGVHINGRIVDSAFTLTFDPVYDNLVEACKAATNAGIKEAGIDVRMSDIGAAIQEVMESYEVEIKGETFPVKCIRNLNGHSIGHYTIHGGKTVPIVKGGDQTKMEEGETFAIETFGSTGKGYVRDDMETSHYAKRSDAPKVALRVSSAKTLLNSITKNFGTLPFCRRYLDRLGHDKYLLGLNNLVSAGIVEAYPPLCDIKGSYTAQSEHVSFFPSV
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX8C_HUMAN
Sequence: MPLLRGRCPARRHYRRLALLGLQPAPRFAHSGPPRQRPLSAAEMAVGLVVFFTTFLTPAAYVLGNLKQFRRN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8C, mitochondrial, Cytochrome c oxidase polypeptide 8 isoform 3, Cytochrome c oxidase polypeptide VIII isoform 3, COX VIII-3, Cytochrome c oxidase subunit 8-3, COX8-3, Cytochrome c oxidase subunit VIIIC.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: TATA_LARHH
Sequence: MGSFSIWHWVIVLVVVVLIFGTKKLRNVGQDLGGAVKGFKEGMKSEGEDAAQTPPAAQKEGGRVIDAEPADKK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ALBA2_SULTO
Sequence: MTVKKPNEILISRTKRVEDYVLDVIVMFNQGYDEVELKGVGNSIYKAVEVYNQLKDRLGDGIILEKADIGSEVKDRRRISYISIKLKRVY
What is the function of this protein?
Binds double-stranded DNA tightly but without sequence specificity.  It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture.  However, it does not significantly compact DNA.  Binds rRNA and mRNA in vivo.  May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).
What are the official names of this protein?
DNA/RNA-binding protein Alba 2.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: PHT13_PETHY
Sequence: MAKDQLQVLNALDVAKTQLYHFTAIVIAGMGFFTDAYDLFCISLVTKLLGRIYYFHEGAPKPGILPSGISAAVNGVAFIGTLSGQLFFGWLGDKLGRKKVYGMTLMLMVICSIACGLSFGKTANGVIATLCFFRFWLGFGIGGDYPLSATIMSEYANKKTRGAFIAAVFAMQGFGILAGGIVALIVSAGFKNAYPAPTYSAHGKDSTPPEADYVWRIIVMIGALPALLTYYWRMKMPETARYTALVAKNTVKAAADMSKVLNVEIEEDKATVEKIEENGNSFGLFSKEFLRRHGLHLLGTTSTWFLLDIAFYSQNLFQKDIFSKIGWIPPPETMNALDEVFRIARAQTLIALCSTVPGYWFTVAFIDKMGRFAIQLMGSFFMTVFMFALAIPYDHWTKKENRIGFVIMYSLTFFFANFGPNATTFVVPAEIFPARLRSTCHGISAAAGKAGAIVGAFGFLYAAQSTDPKKVDAGYPTGIGVKNALIVLGCVNFLGMLSTLLVPESKGKSLEEMSKENEGEEENYGTETKGENAQTVPV
What is the function of this protein?
Low-affinity transporter for external inorganic phosphate (Pi) probably involved in the acquisition of phosphate released by arbuscular mycorrhizal (AM) fungi during AM symbiosis.
What are the official names of this protein?
Low affinity inorganic phosphate transporter 3, PhPT3, PhPht1;3, Arbuscular mycorrhiza-induced phosphate transporter PT3, AM-induced phosphate transporter PT3, H(+)/Pi cotransporter PT3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Present on the periarbuscular membrane in cells containing arbuscules during arbuscular mycorrhizal (AM) symbiosis with AM fungi.
Protein: RLMN_CORGB
Sequence: MATPVPLVFNAPKRGMPPTHFADLNDEARIEALKELGLPKFRLNQIARHYYGRLEADPLTMTDLPEGARQEVKDALFPTLMSPLRVIETDDDTTQKTLWKLHDGTLLESVLMRYSDRSTLCISSQAGCGMACPFCATGQGGLDRNLSIGEIVDQVRNAAATMQAEGGRLSNIVFMGMGEPLANYKRVVSAVRQITQPSPAGFGISQRSVTVSTVGLAPAIRKLADEEMSVTLAVSLHTPDDELRDTLVPVNNRWPVAEVLDAARYYADKSGRRVSIEYALIRDVNDQDWRADMLGEKLHKALGSRVHVNLIPLNPTPGSKWDAAPKARQDEFVRRVIAKGVPCTVRDTKGQEIAAACGQLAAEESA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOSO_STAAN
Sequence: MLFKEAQAFIENMYKECHYETQIINKRLHDIELEIKETGTYTHTEEELIYGAKMAWRNSNRCIGRLFWDSLNVIDARDVTDEASFLSSITYHITQATNEGKLKPYITIYAPKDGPKIFNNQLIRYAGYDNCGDPAEKEVTRLANHLGWKGKGTNFDVLPLIYQLPNESVKFYEYPTSLIKEVPIEHNHYPKLRKLNLKWYAVPIISNMDLKIGGIVYPTAPFNGWYMVTEIGVRNFIDDYRYNLLEKVADAFEFDTLKNNSFNKDRALVELNYAVYHSFKKEGVSIVDHLTAAKQFELFERNEAQQGRQVTGKWSWLAPPLSPTLTSNYHHGYDNTVKDPNFFYKKKESNANQCPFHH
What is the function of this protein?
Catalyzes the production of nitric oxide.
What are the official names of this protein?
Nitric oxide synthase oxygenase, NOSoxy-like protein, SANOS.
What is the protein family that this protein belongs to?
Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
Protein: RCOM2_PARXL
Sequence: MKSSESAAATASERRAETFQHKLEQFNPGIVWLDPQGHVSAFNDVALHILGPAGEQSLGVAQDHLFGIDVVQLHPEKSRDKLRFLLQSRDAGGCPVRSPPPVAMMINIPDRILMIKVSKMTGAAGTCGSCMIFYDVTDLTTEPSSQPAGASVPAPRRLFKIPVYRKSRVILIDLKDIVRFQGDGHYTTIVTKDERYLSNLSLADLELRLDSSVYLRVHRSHIVSLPYAVELVKLDESVNLVMDDAEQTQVPVSRSRTAQLKELLGVV
What is the function of this protein?
One-component, b-type heme-containing aerobic sensor and transcriptional regulator that responds to CO by activating the expression of the oxidation operon cox.
What are the official names of this protein?
Heme-containing CO-sensing transcriptional regulator RcoM 2, Regulator of CO metabolism 2, RCOM-2.
What are the subcellular locations of this protein?
Cytoplasm.