PharMolix/UniProtQA huggingface dataset:
Protein: UHRF2_MOUSE
Sequence: MWIQVRTIDGSQTRTIEDVSRKATIEELRERVWALFDVRPECQRLFYRGKQLENGYTLFDYDVGLNDIIQLLVRPDSSLPSTSKQNDAQVKPSSHNPPKVKKTARGGSSSQPSTSARTCLIDPGFGLYKVNELVDARDVGLGAWFEAHIHSVTRASDGHSRGKTPLKNGSSYKRTNGNVNHNSKENTNKLDNVPSTSNSDSVAADEDVIYHIEYDEYPESGILEMNVKDLRPRARTILKWNELNVGDVVMVNYNVENPGKRGFWYDAEITTLKTISRTKKEVRVKVFLGGSEGTLNDCRVMSVDEIFKIEKPGAHPISFADGKFLRKNDPECDLCGGDPDKTCHMCSCHKCGEKRDPNMQLLCDECNMAYHIYCLSPPLDKVPEEEYWYCPSCKTDSSEVVKAGERLKLSKKKAKMPSASTESRRDWGRGMACVGRTKECTIVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFEDEVDRGDEFTYTGSGGKNLAGNKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYPSEKEGKKTKGQSKKQGSEATKRPASDDECPGDSKVLKASDSTDAVEAFQLTPQQQRLIREDCQNQKLWDEVLASLVEGPNFLKKLEQSFMCVCCQELVYQPVTTECFHNVCKDCLQRSFKAQVFSCPACRHDLGQNYVMVLNETLQTLLDLFFPGYSKGR
What is the function of this protein?
E3 ubiquitin ligase that plays important roles in DNA methylation, histone modifications, cell cycle and DNA repair.  Acts as a specific reader for 5-hydroxymethylcytosine (5hmC) and thereby recruits various substrates to these sites to ubiquitinate them (PubMed:23434322, PubMed:28402695).  This activity also allows the maintenance of 5mC levels at specific genomic loci and regulates neuron-related gene expression (PubMed:28115522).  Participates in cell cycle regulation by ubiquitinating cyclins CCND1 and CCNE1 and thus inducing G1 arrest.  Ubiquitinates also PCNP leading to its degradation by the proteasome.  Plays an active role in DNA damage repair by ubiquitinating p21/CDKN1A leading to its proteosomal degradation.  Promotes also DNA repair by acting as an interstrand cross-links (ICLs) sensor.  Mechanistically, cooperates with UHRF1 to ensure recruitment of FANCD2 to ICLs, leading to FANCD2 monoubiquitination and subsequent activation.  Contributes to UV-induced DNA damage response by physically interacting with ATR in response to irradiation, thereby promoting ATR activation (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase UHRF2, NIRF, Np95-like ring finger protein, Nuclear protein 97, Nuclear zinc finger protein Np97, RING-type E3 ubiquitin transferase UHRF2, Ubiquitin-like PHD and RING finger domain-containing protein 2, Ubiquitin-like-containing PHD and RING finger domains protein 2.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Enriched at genomic loci that are enriched for 5-hydroxy-methylcytosine (5hmC).
Protein: GCSH_CLOBK
Sequence: MKVLNNLLYTGDHEWVRVEDNKAYIGISDCAQRMLSDIVFVELPEVDDEIAKGETFATIESVKAASDSYMPVSGTIVEINEELEDNPAALNEDPYGSWIAAIEMSDKNELEELIKPEVYEKICEELDKEA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: GH109_SHEB9
Sequence: MHNIHRRNFLKAAGAATAGLVTANIALNAYASSVAPKPQAGKSVIGLIAPKMDVVRVGFIGVGERGFSHVEQFCHLEGVELKAICDTHQAVLDRAIDHIVKQNRPKPAVYTGNDLSYRDLLSRDDIDIVIISTPWEWHAPMAIETMESGKHTFVEVPMALTVEECWQVVDTAERTQKNCMMMENVNYGREELMVLNMVRQGVFGELLHGEAAYIHELRWQMKEIDHKTGSWRTYWHTKRNGNLYPTHGLGPVSQYMNINRGDRFDYLTSMSSPALGRALYAKREFPADHERNQLKYINGDINTSLIKTVKGRTIMVQHDTTTPRPYSRHNLIQGTNGVFAGFPNRIAVENGGFGQSYHEWDMDMQKWYDKYDHPLWQRIGKEAEINGGHGGMDFVMLWRMIYCLRNGEALDQDVYDGASWSVVNILSEHSLNDRSNSVTFPDFTRGAWQTAKPLGIVGA
What is the function of this protein?
Glycosidase.
What are the official names of this protein?
Glycosyl hydrolase family 109 protein.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
Protein: IHFA_ECOLC
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RLME_PARPJ
Sequence: MAKNKFNTAWLHDHINDPYVKMAQREGYRARAAYKLKEIDEQDRLIRPGQVIVDLGSVPGSWSQYARNKLAKGAQRDAEREGGIDGTIIALDILPMEPIADVTFIQGDFREDTVLGQLEELVGERQVDLVISDMAPNLSGVAVADAARIEHLCDLALEFSQNHLKQDGALLVKCFHGSGYSQIVEKFKHQFKVVAARKPKASRDKSSETFILGKHLKRPA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUR3_YEAST
Sequence: MGEFKPPLPQGAGYAIVLGLGAVFAGMMVLTTYLLKRYQKEIITAEEFTTAGRSVKTGLVAAAVVSSWIWCSTLLTSSTKEYADGIFGGYAYAAGACFQIIAFAILAIKTKQMAPNAHTYLELVRTRYGKIGHGCYLFYAIATNILVTSMLLTSGSAVFSDLTGMNTIASCFLLPVGVVVYTLFGGIKATFLTDYMHTCVIIIIVLVFAFKVYATSDVLGSPGKVYDLVREAAKRHPVDGNYQGEYMTMTSKSAGILLIINLIGNFGTVFLDNGYWNKAISASPAASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSPNFPTYPDPLTSFQANSGLVLPAAAIAIMGKGGAVASLLMIFMAVTSAMSAELIAVSSVFTYDIYREYIDPRASGKKLIYTSHVACIFFGLAMSGFSVGLYYGGISMGYIYEMMGIIISSAVLPVVLTLCSKDMNLVAAVVSPILGTGLAIMSWLVCTKSLYKELTVDTTFMDYPMLTGNLVALLSPAIFIPILTYVFKPQNFDWEKMKDITRVDETAELVQADPDIQLYDAEANDKEQEEETNSLVSDSEKNDVRVNNEKLIEPNLGVVISNAIFQEDDTQLQNELDEEQRELARGLKIAYFLCVFFALAFLVVWPMPMYGSKYIFSKKFFTGWVVVMIIWLFFSAFAVCIYPLWEGRHGIYTTLRGLYWDLSGQTYKLREWQNSNPQDLHVVTSQISARAHRQSSHFGQVDEII
What is the function of this protein?
Required for active transport of urea.
What are the official names of this protein?
Urea active transporter.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COFH_METM6
Sequence: MDLMSFKEKEISKKECLELFEDTENFFDVIKLADSLRKDIVGDTVTYVVNANINFTNICSGTCGFCAFKAEPDDSNAFFLNPNEVAKKALEAKKTGATEVCIQGGLLKEIDTHFQAEILKKVKEITESFGKIDVHAFSPMEVKSAAENAGLSVKEALKILKENGLNSMPGTAAEILNDKIRSEICPTKLKTSEWIDVVTNAHKTGIKTTCTMMYGHIEENKHLAEHLSILRKIQKETGGFTEFVPLTFLHENAPLYHLDRVKNGASGMLDLKTYAVSRIFFKDCIKNIQTSWVKLGTKLSQVSLNCGANDIGGTLMEESISKAAGGSYGTYMSEEKLKDMILAVGRTPKQRNTAYEIIE
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: HBD_BRADU
Sequence: MAAVIKKVGVIGAGQMGNGIAHVAALAGFDVVLNDVSADRLKSGMATINGNLARQVSKKVVTEEAKTKALSRIVAAEKLDDLADCDLVIETAVEKEEVKRKIFHELCAVLKPEAIVASDTSSISITRLAAATDRPERFIGIHFMNPVPLMELVELIRGIATDDATFEASKEFVAKLGKQVAVSEDFPAFIVNRILLPMINEAIYTLYEGVGNVEAIDAAMKLGAHHPMGPLELADFIGLDTCLSIMQVLHEGLADSKYRPCPLLVKYVEAGWLGRKTQRGFYDYRGAKPVPTR
What are the official names of this protein?
3-hydroxybutyryl-CoA dehydrogenase, Beta-hydroxybutyryl-CoA dehydrogenase, BHBD.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: GLMM_NOSP7
Sequence: MVSSITRIPGIPGDSPSEAEGLGKGIESSFGLNLIPLPANPLFGTDGIRGRVGELLSAPLALQVGFWTGIVLRNHATQIGPVILGQDSRNSSDMLAMALSAGLTAAGLEVWYLGLCPTPCIAYLTSISDAIGGVMISASHNPPEDNGIKVFGANGGKLPQILQAEIEAGLRGKISPIAKVSNCGRHYSRFELVGHYGDALKKPLNSTLNLQGMKIVLDLAWGAAVGLAPSVFTEMGAEVICLHNEADGDRINVNCGSTHLDILAATVQEHNADIGFAFDGDADRVLAVDNTGRQVNGDYILYLWGRHLQKNQQLPDNLIVSTVMANLGFEKAWQQIGGKLIRTAVGDQYVQAEMQRTGGMLGGEQSGHILCRHYAVTGDGLLTALHMAALVKEAGVSLAELVDQSFQTYPQILRNVRVTDRDRRLGWQDCEPVQQAIALAEAAMGDSGRILVRASGTEPVIRVMVEAANAELTNYWTNELVSKVQQHLMD
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TGA1W_MAIZE
Sequence: MDWDLNAAGAWDLAELEQDHAAAAPSSGGHAANAAAAGTGTESRPPAPGAAGAPAECSVDLKLGGMGECEPGAARREREAAAGAAKRPRPAGPGGQQQQQCPSCAVDGCRADLGKCRDYHRRHKVCEAHSKTPVVVVAGREMRFCQQCSRFHLLAEFDADKRSCRKRLDGHNRRRRKPQPDTMASASFIASQQGTRFSPFAHPRLEASWPPGVMKTEESPYHITHQIPLGSSSSSRQQHFVALGAATPAYAKEGRRFPFLQEGEISFATGVVLEPPAAAPACQPLLRTGAPSESSGAGGSKMFSDQGLARVLDSDCALSLLSAPANSSGIDVSRMVRPTEHVPMAQQPVVPGLQFGSASWFPRPQASTGGSFVPFCPAAVEGEQQLNAVLGPNDSEVSMNYGGMFHVGGGSGGGEGSSDGGTSSSMPFSWQ
What is the function of this protein?
SBP transcriptional regulator probably involved in the domestication of maize (PubMed:16079849).  Acts as a transcriptional repressor binding to a 5'-GTAC-3' motif (PubMed:25943393).  May repress the growth of lateral branches in length and numbers (PubMed:25943393).
What are the official names of this protein?
Teosinte glume architecture 1.
Protein: ARGR_STAA8
Sequence: MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSRDIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPGNAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORR26_ORYSJ
Sequence: MDATAFPYGLRVLVVDDDPTWLKILEKMLRKCSYEVTTCGLARVALDILRERKNKFDIVISDVNMPDMDGFKLLEHIGLEMDLPVIMMSIDGETSRVMKGVQHGACDYLLKPVRMKELRNIWQHVYRKKMHEVKEIEGNDSCDDLQILRNSFEGLDEKSLFMRSDSDTMRKRKDVDKDHADQESSDGNTVKKARVVWSVDLHQKFVNAVNQIGFDKVGPKKILDLMNVPGLTRENVASHLQKYRLYLSRLQKQNEERILGAARQDFSHKGTSENLNLRSSFQEQPSNIANGYPHASQNIQTQANMLDSQLEDTKSTVPLPVPDKKRTLASDAADSQNVTSASSLGGVLSFKSMPVNQDRKPSETMILECQAWTGGIPSKQFMQYPKHNHERCDLLGDYSCLPKPDLEHPVGPSNLYAPPPLISMSCGMEGDARDFSDVKPAIMDCIKSLSPALTCTVDSVSVQLSDSVVTSIDGDLKSSGVDGLPSIKDCCLDQTNSQGSLRPSQEPSIIGSTELASLPEDLPSYPLHGVSLENIGLSSIDLLNYSDAMILSGLQSNWYDDLEFSSEMMDYPSIDECLFASS
What is the function of this protein?
Transcriptional activator that binds specific DNA sequence.  Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  May directly activate some type-A response regulators in response to cytokinins.
What are the official names of this protein?
Two-component response regulator ORR26, OsRRB6.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ICP46_FRG3G
Sequence: MANFVTDSRNGLTISCAPQDQSHLHPTIRALVMEGDSVIFRGLPHPDIHREAPPAGLRLKDCLVYDSYEGALVNVFWHGGQWWFCTNKKLSIDRASWSASPGSFKRAFVNCLRKMWRDDRSWADLFDRSYMPSFCDANLDKDLGYVFMVFDPEERIVCSDTEQRLRLLATFDRCTNSHSYECSLTLTCGTEVEVPRPICLKNEREFLLHLRSQDPCRVAGVVLIDALDIHYKILPSEYTKVLDARGEQPRLLNRMFQLMEMGPEGEAHIEVLCRYFSDARVAMERAWDVRERIVQCYLDLTEPDSEPQVWMTRRLMEIVRGCRPGTERTMIDEFLRTMTTGQRKAFYKKHACLAGGDNAWISSDAPIKQAKTVQDLVEFPDDNCQDMDELFVVRA
What are the official names of this protein?
Immediate-early protein ICP-46.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 393L family.
Protein: MHPB_ECOLU
Sequence: MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPELVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSGIDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGRFTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVISAAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWVAAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: PUKI_ARATH
Sequence: MEPVIIGALILDVHAKPSTTPISGTTVPGQVLFAPGGVARNVADCIFKLGITPFMIGTLGLDGPANVLLKEWKLSMKGILRREDISTPIVSLVYDTNGEVAAGVAGVDAVENFLTPEWIQRFEYNISSARLLMVDANLSSLALEASCKLAAESSVPVWFEPVSVTKSQRIASIAKYVTIVSPNQDELIAMANALCAKNLFHPFRSDENKLSIEDMFRALKPAILVLLKNGVKVVIVTLGSNGALLCSKGNPKKALNIDRKFLRSGEVFKRVQSVCSPNRFSELGSNRSPSLFAMHFPTIPAKVKKLTGAGDCLVGGTVASLSDGLDLIQSLAVGIASAKAAVESDDNVPPEFKLDLISGDAELVYNGAKMLMVHQSML
What is the function of this protein?
Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP) (PubMed:31907295).  Catalyzes the first step in a pseudouridine degradation pathway (PubMed:31907295).  Acts together with the pseudouridine 5'-phosphate glycosidase PUMY in the peroxisome to prevent toxic pseudouridine monophosphate accumulation (PubMed:31907295).
What are the official names of this protein?
Pseudouridine kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: Y3078_CLOK1
Sequence: MRILIDGDACPGKYIIENIARENDIEVIIYCDTNHILKSNYSTVVTVDSGFQSVDMVIVNKVRSGDIVVSQDYGVAAMVLGKKAYAINPKGYIYHEGNMDKLLFERYISSKVRRTGGRTSNPKKRTKEDDKRLRENLFQLILNGKVYKGEDW
What are the official names of this protein?
UPF0178 protein CKR_3078.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: LPXA_SALTI
Sequence: MIDKSVFIHPTAIVEDGAVIGANAHIGPFCIVGPQVEIGEGTVLKSHVVVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNAYKLLYRSGKTLDEAKLEIAELAEKHPEVKAFTEFFERSTRGPIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPSB_BACSH
Sequence: MLADKVKLSAKEILEKEFKTGVRGYKQEDVDKFLDMIIKDYETFHQEIEELQQENLQLKKQLEEASKKQPVQSNTTNFDILKRLSNLEKHVFGSKLYD
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation (By similarity).
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: DNAE2_RALSO
Sequence: MNAPTPLPIGLPDYAELHCISNFTFLTGASHPHELVARAQAFGYRALALTDECSVAGTVRAHMAAKEAGLKLIIGSRFTVRDAQGEPWLRLVLLAQDIDGYGNLCECITQARLAAPKGDYRLLADDLAAPAGELAHLRGMPHCLAILLPDYDPDPRHLLAQAQWCRQVFGDRLSMALELPLRHADDRHRGTVAAVSEQTDVPMVATGDVAMHSRQRKPLHDVLTAIRLSRPIAECGLALAPSAEQAMRTRMQLAFFYQGERGAQVLRRSVELASLCDFSLDEIAYEYPHEVVPEGQTPAGYLLAEVMAGAARRYGKDIPSKVRAQLDEELALIAELRYEPFFLTVYDVVRFARSQSILCQGRGSAANSAVCYCLGITEVNPESGNTLFARFLSRARNEPPDIDVDFEHQRREEVIQYIYKKYGVTRTALAAALITYRTRSALRDVGRALGIDLGVIEQVAKAQAWWDGRHEFAQRAGQQGLDPESPLVQRWAGLIEQLRGFPRHLSQHVGGFVIAQGKLSRLVPIENAAMPERRVIQWDKDDLESLRLLKVDVLALGMLTAIRRTLDMLDALPGRRAHYGAPDKLAMQHLPDEDTATYEMICRAETIGVFQIESRAQQSMLPRLRPRTYYDLVIQVAIVRPGPIQGGMVHPYLQRREAVRNGNPDCVTYPGPEVKAVLERTLGVPIFQEQVMEIAMKAGGFTADEADRLRRDMAAWKRKGNLTQHQARLMKEMVEVRHYDPAFVEALCRQMEGFAEYGFPESHAAGFARLAYVSSFLKCHEPAAFFAALLNSQPMGFYSPSQLVQEARRSRVRVLPADVTASAWDSTLHARPDGAGGQPDIRLGLNRIRGMRPAAGERIVVARAQAPFSSVEDLAHRAALDRHDLSVLAAANALLSLAGHRRQALWQTLALQEPGQDHALLRQARPVEAPLVLPAPSLGEEVVADYGSLGLSLQSHPLSLLRPRLERMRFVTAAALAGYRNGQLARACGIVTVRQRPGTAKGTIFVSIEDETGAVNVVLWPRLIERQRREVLHARLLGVYGKWQCERETRHLVAQHLVDLTPLLGRLASSSRDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_ECOLC
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_MYCMM
Sequence: MADPARARRLAKRITTIVASAIEYEIKDPGLVGVTITDAKVTADLHDATVYYTVMGPTLDDEPDYAAAAAALERAKGVLRTKVGAGTGVRFTPTLTFTRDVTSDTVHRMDELLARARAADADLARVRVGAKPAGEADPYRDRGSADEPSDAGGLVIRTSDGLEAENTGDDYQAED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_THEP1
Sequence: MSGKLTIITGPMYSGKTTELLSFVEIYKLGKKKVAVFKPKIDSRYHSTMIVSHSGNGVEAHVIERPEEIRKYIEEDTRGVFIDEVQFFSPGLFEVVKDLLDRGIDVFCAGLDLTHKQNPFETTALLLSLADTVIKKKAVCHRCGEYNATLTLKVAGGEEEIDVGGQEKYIAVCRDCYNTLKKRV
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_PSEAE
Sequence: MSTPTPKVGFVSLGCPKALVDSERILTQLRMEGYEVVPTYEDADVVVVNTCGFIDSAKAESLEVIGEAIAENGKVIVTGCMGVEEHAIRDVHPSVLAVTGPQQYEQVVTAVHEVVPPKTEHNPLVDLVPPQGVKLTPRHYAYLKISEGCNHSCSFCIIPSMRGKLVSRPVGDVLSEAERLVKAGVKELLVISQDTSAYGVDLKYKTDFWNGQPVKTRMKELCEALSSMGVWVRLHYVYPYPNVDDVIPLMAAGKLLPYLDIPFQHASPKVLKAMKRPAFEDKTLARIKQWREICPELTIRSTFIVGFPGETEEDFQYLLDWLTEAQLDRVGCFQYSPVEGAPANELGLEPVPDEVKQDRWERFMAHQQAISAARLQLKVGKEIEVLIDEVDEQGAVGRSWADAPEIDGNVFVDSDELKPGDKVRVRITDADEYDLWAELV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_ECO57
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGTVQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIADYEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDKLEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHYS_METTE
Sequence: MDFEASAKILTTPVKGAKIVSNMTVDELVREYAGCAFGAGRLAKAVDIYYEMLASEKTTKFFGLAGAMTPAGMRNIIADLIRDGYIDVLVTTGANMVHDTVEALGLHHYKGSDCTNDIQLRHECIDRIYDVYLPDQHFTDLEEFLQGVYAGLPQEKLSIRQVLTEIGKNLDDDSSILKTAAEMGVPVYCPALQDSVIGLQAWLYKEGNPLHVDAFADMHEFMEICFETESAGAMLLGGGVPKNYILQSMLVTPRSFDYAIQLTMDHPETGGLSGATLDEAQSWGKVGENAKSVTVYADSTITLPLIVSAVRTRLSKR
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: RS9_BEII9
Sequence: MAETLSSLQDLKAATAVPTEEAPVYAQKLDAFGRAYATGKRKDAVARVWIKPGSGKVTVNGRPLDVYFARPVLRMILQQPLGVAKRVDQYDLMVTVAGGGLSGQAGAVRHGLAKALVNYEPELRSALKKEGFLTRDSRTVERKKYGKKKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: OBG_CLOP1
Sequence: MFIDTAKIFVKSGDGGHGSVSFRREKYVPLGGPDGGDGGKGGDVTFVVDPGMTTLLDFKYKRKFVAGRGQDGQGSKCYGRDGENLTIKVPMGTIIRDVETNKVMADLSHRDDTYTICRGGKGGKGNCKFCTPTRQAPTFAEPGMPGEERWVALELKLLADVGLLGFPNVGKSTLLSVVTKAKPKIANYHFTTLKPNLGVVAVPGIEPFVMADVPGIIEGASEGVGLGLDFLRHIERTRLLIHVVDISGVEGRDAVEDFKRINEELKNYSVKLWDRPQIVVANKCDMLFDEEIFENFKAEVNKMGFDKVFKMSAATSQGVEEVIKEAARMLKDIPVTDLEIPEDERFIPEDKKFTYTINPIEEDGLKVYVVEGSFVDRLLLAVNVNDPDSLRYFHKVLNNKGIFHELREMGIEDGDMVRLNDFEFEYLL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_STAA3
Sequence: MKCPKCNSTQSKVVDSRHADELNAIRRRRECENCGTRFTTFEHIEVSQLIVVKKDGTREQFSREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDEGHTEVSSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILSENKRSDA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.