PharMolix/UniProtQA huggingface dataset:
Protein: ORML3_MOUSE
Sequence: MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNLGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQVHFILNTVSLMTVLIPKLPQLHGVRIFGINKY
What is the function of this protein?
Negative regulator of sphingolipid synthesis.  May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (By similarity).
What are the official names of this protein?
ORM1-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the ORM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: VMPA1_TITPA
Sequence: DDCIVVEYYIVTDSRFTQRFDSDQAVTDYVTVMFTGVQNLIDTLNLDIKVRLLGVTPYHKESEPSFIDDSLLPGHETYVDARKIVRNMKFYFCNHNTGLAKSADIIMLLITRKMGVLDPGDTDISEIAGASSISSVCQRCNNVGACVDNSDYNERADTVAHESVHLLGSPHDGEGPNGLGLPNSPGAANCPDSDGYIMGTRNEQNGKKFSECTKQCVKYLLSLPRASCVYENCSK
What is the function of this protein?
Acts as a metalloprotease.  Penetrates intact tissue and specifically cleaves the vesicle-associated membrane protein 2 (VAMP2) (part of the SNARE complex) involved in pancreatic secretion, thus disrupting the normal vesicular traffic (By similarity).
What are the official names of this protein?
Venom metalloproteinase antarease-like TpachMP_A, VMPA.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXD_CHESB
Sequence: MTEPAFFAPARRFEVGEIAALTGARLRDASQEKITISRLAPAAEGGEETLVFIDGRRHASRIGSVRAAALLCSEELAENAPDGVAVLVSPKPQQAFAMVARLLFPEANRPQPVTGETGVSPRAVIAEGAVVEDGAIIEAGAVIGVGASVGRGTIVGPNTVIGARCSIGRDGYVGPNVMLQYAVIGDRVIIHPGAQIGQDGFGFLPGPNGFEKNPQIGRVIIQDDVEIGANTTIDRGALSDTIIGEGTKIDNLVQIGHNVHIGRRCVIAGLCGLSGSVKLGDYVMLGGQVGIADHITIGNRAQLAASSGVMDDVPEGERWAGVPAKPMRQAFREIAALRSLVQDMRKGSKG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: LUTA_MACCJ
Sequence: MKVSLFSTCLVDVFEKRVGIATVELLEKLGCEVDFPAAQVCCGQPAYNSGYHEETKKAAKNMIKAFEQSEVVVAPSGSCVTMFKHYPDLFKNDAKWQARAQELADKTYEVTQFIVEVLGITNVGAKLDGVATIHPSCHMTRLLGNVTAPAKLLNEVEGLEVVELPKYYNCCGFGGTFAVKMSDVSGEMVDEKVDCIVESGADYLVGGDCSCLMNIDGRLRRRGVDVKAVHIIEILNNQVEAVTTR
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: TRP7_RHOPR
Sequence: SPATMGFAGVR
What is the function of this protein?
Myoactive peptide.  Increases the amplitude and frequency of spontaneous contractions and tonus of hindgut muscle.
What are the official names of this protein?
Tachykinin-related peptide 7, Rhopr-TRP-7.
What are the subcellular locations of this protein?
Secreted.
Protein: RNZ_MYCTO
Sequence: MLLTHLHSDHIAELGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity).
What are the official names of this protein?
Putative ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: IAA3_ARATH
Sequence: MDEFVNLKETELRLGLPGTDNVCEAKERVSCCNNNNKRVLSTDTEKEIESSSRKTETSPPRKAQIVGWPPVRSYRKNNIQSKKNESEHEGQGIYVKVSMDGAPYLRKIDLSCYKGYSELLKALEVMFKFSVGEYFERDGYKGSDFVPTYEDKDGDWMLIGDVPWEMFICTCKRLRIMKGSEAKGLGCGV
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Plays a central role in auxin regulation of root growth, in gravitropism, and in lateral root formation (PubMed:9895319).  Regulated by an auxin-induced protein turnover (PubMed:14617065).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.  When activated by cytokinin, restricts the expression of the PIN genes to the vascular transition zone (PubMed:19039136).  Induction of SHY2 in the vascular transition zone restricts BRX expression to down-regulate PIN3 and thus limit meristem growth, but proper SHY2 expression requires BRX (PubMed:21149702).  Involved in meristem growth and in determining its size (PubMed:20605455).  May participate in strigolactone signaling to regulate meristem size and lateral root formation (PubMed:23425316).
What are the official names of this protein?
Auxin-responsive protein IAA3, Indoleacetic acid-induced protein 3, Short hypocotyl, Suppressor of HY2.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YIDC_AZOVD
Sequence: MDIKRSILLVALAVVSYLLVLQWNQDYGQAALPPQNAVAQSASPALPETVPGDSSTSADVPTAGSGNQVPDSAASTAGSDLIQVRTDVLEVAIDPRGGDIVQLKLPKFPRRQDHPEIPFQLFDNGSERLYLAQSGLTGTNGPDARADGRPLYVSEQRSYQLADGQDSLVVDLKFSDGGVDYVKRFTFKRGAYDLEVRHQIANHSEQPWSGNLFAQLKRDASADPSSTTATGTATYLGAALWTSEEPYRKVSMGDMDDKNLRETVQGGWVAWLQHYFVTAWVPNKDDTNLVATRKDSQGNYIIGFTGSTLNIPAGATGETVTRLYAGPKDQNQLEALSPGLELTVDYGFLWFIAQPIFWLLELIHALLGNWGWSIIVLTVIIKLAFFPLSAASYRSMGRMRAVAPKLQALKEQHGEDRQKLSQAMMELYKKEKINPLGGCLPILVQMPVFLALYWVLLESVEMRQAPWLGWITDLSVKDPYFILPIIMGATMFFQQTLNPTPPDPMQARVMKLMPIIFTFFFLWFPAGLVLYWVVNNVLSIGQQWYITRQIEKAAQLA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDB3T_OPICY
Sequence: MQYKTFLVISLAYLLVADEAAAFWATLAKGALKLIPTIANAFSSKSKKRREINNVFEPYHENLDLELERFLSQLQ
What is the function of this protein?
Amphipathic peptide with probable antimicrobial activity.
What are the official names of this protein?
OcyC3, Non-disulfide-bridged peptide 4.3, NDBP-4.3.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Medium-length antimicrobial peptide (group 3) family.
Protein: PSTB_SHISS
Sequence: MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DNAK_THET2
Sequence: MAKAVGIDLGTTNSVIAVLEGGKPVVLENAEGERVTPSVVAFRDGETLVGRMAKRQAVLNPEGTIFEIKRFIGRRFEEVQEEAKRVPYKVVPGPDGGVRVEVKGKLYTPEEISAMILRKLVEDASKKLGEKITKAVITVPAYFNNAQREATANAGRIAGLEVLRIINEPTAAALAYGLDKKGNETVLVFDLGGGTFDVTVLEIGEGVFEVKATSGDTHLGGSDMDHAIVNWLAEEFKKEHGVDLKADRQALQRLIEAAEKAKIELSSTLETTISLPFIALDPASKTPLHLEKKLTRAKFEELIQPLLKRLRGPVEQALKDAGLTPAQIDEVILVGGATRVPAVQQVVRELLGKEPNRSVNPDEVVAMGAAIQAGVLMGEVRDVVLLDVTPLSLGVETKGGVMTVLIPRNTTIPTRKCEIFTTAEHNQTAVEIHVLQGERPMAQDNKSLGRFRLEGIPPMPAGVPQIEVCFDIDANGILHVTAKERSTGREASITIQNTTTLSEEEIQRIIEEAKRHAEEDRRRREHAELKNALDSARVQAERVLQERQGAPEARARLEAAIGKAKELVERDAPDPELKAATEELLKAVEEYEKGAQAASGKGPDDVIDADYKPAD
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MURD_DINSH
Sequence: MIPVRGFSGETIAVLGLGRSGLATARALRAGGATPLCWDDNTEARARAEAEGFACAPLKHADAFDGVAALITSPGIPHLYPTPNPTIALAMSLGIPVDNDIGLFFRSFATPDWDEFDSLPRVIAVTGSNGKSTTSALIHHVLTAAGRPTQLAGNIGRGVLDIDPGEDGGIVVLELSSYQTELARALTPDIAVFTNLSPDHLDRHGGMGGYFAAKRRLFTIGGPDRAVIGTDEPEGLFLASQLSVAPADDRVIRVTSAKPSGPGWVVSARKGFLAEHRKGRQTGSIDLRPIPGLPGAHNHQNAACAYAACRSLGLAPRQIEAGFASFKGLPHRSQIVGTANGVTFVNDSKATNVDSAAKALQAFDRIRWIAGGLEKEGGLAALTPHLGGVRKAYLIGRSAAEFALGIPDTPHEVCETMARAVAAAVAEAEPGDTILLAPAAASFDQYDNFERRGEDFIAEVAKYL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_THANO
Sequence: MSQSVSERTRIKSDRYESGVIPYAKMGYWDAAYTVKDTDVLALFRITPQPGVDPVEAAAAVAGESSTATWTVVWTDLLTACERYRAKAYRVDPVPNSPDVYLAFNAYECDLFEEASLSNLTASIIGNVFGFKAVAALRLEDMRIPHSYLKTFQGPATGIVVERERLNKYGTPLLGATVKPKLGLSGKNYGRVVYEGLKGGLDFLKDDENINSQPFMRWRERFLNCLEGINRAAAATGEVKGSYLNITAATMEEVYKRAEYAKAIGSVLVMIDLVMGYTAIQSIAYWARENDMLLHLHRAGNSTYARQKNHGINFRVFCKWMRMSGVDHIHAGTVVGKLEGDPLMIKGFYDILRLTELEVNLPFGVFFEMDWASLRRCMPVASGGIHCGQMHQLIHYLGDDVVLQFGGGTIGHPDGIQAGATANRVALEAMVFSRNEGADFFNNQVGPQILRDAAKTCGPLQTALDLWKDISFNYTSTDTADFAETATANR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPA43_YEAST
Sequence: MSQVKRANENRETARFIKKHKKQVTNPIDEKNGTSNCIVRVPIALYVSLAPMYLENPLQGVMKQHLNPLVMKYNNKVGGVVLGYEGLKILDADPLSKEDTSEKLIKITPDTPFGFTWCHVNLYVWQPQVGDVLEGYIFIQSASHIGLLIHDAFNASIKKNNIPVDWTFVHNDVEEDADVINTDENNGNNNNEDNKDSNGGSNSLGKFSFGNRSLGHWVDSNGEPIDGKLRFTVRNVHTTGRVVSVDGTLISDADEEGNGYNSSRSQAESLPIVSNKKIVFDDEVSIENKESHKELDLPEVKEDNGSEIVYEENTSESNDGESSDSD
What is the function of this protein?
DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I (Pol I) which synthesizes ribosomal RNA precursors.  Besides, RNA polymerase I has intrinsic RNA cleavage activity.  Through its association with RRN3 is involved in recruitment of Pol I to rDNA promoters.  In vitro, the A13-A43 subcomplex binds single-stranded RNA.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA43, A43, DNA-directed DNA-dependent RNA polymerase 36 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYV_CALS4
Sequence: MKDIAKTYNPKEFEDRIYSFWMEKGFFTPEIDPEKKPFTIVIPPPNVTGELHMGHALDNTLQDILIRWRRMQGYAALWIPGTDHASIATEIKVLDKIREETGKTKKDLTREEFLEKAWEWKDKYENRILSQLKKLGSSCDWTRTAFTMDEKRSKAVREVFVSLYEKGLIYKGNRIINWCPSCNTALSDAEVEHKEHKGHLWYIKYPVKGEEDYVVIATTRPETMLGDVAVAVHPEDERYRHLIGKTLILPLVGREIPVIADEYVDPSFGTGAVKVTPAHDPNDFEIGVRHNLPFVNIMNENATINENGGKYEGLDRYEAREKIVKDLEEQGLLLKVEEHVHNVGHCYRCDTVVEPLLSEQWFVKMEPLAKPALQVVKEGKIKFVPERFEKIYTNWLENIKDWCISRQLWWGHRIPAWYCEDCGHVTVSREDPVKCEVCGSTNIHQDENVLDTWFSSALWPFSTMGWPEETEDLKYFYPTDVLVTGYDIIFFWVARMIFMSLEFMKEIPFKYVLIHGLVRDALGRKMSKSLGNGIDPLEVIEKYGADTLRFTLVIGNAPGNDMRFSWEKVEHSRNFANKLWNASRYVLLNLDENDTNLYLDNLALADKWILTRYNNIVKEITDNLEKFELGVAASKLYDFVWSEFCDWYIELSKPVLYSDNEEAKKVTKSVLRYVLDNTLRLLHPFMPFITEEIWQNLPHEGESIMVAEWPKYREDLNFEEDAKKAEIIMEAIRAIRNIRAEANVSPSKKAKVIIAVEKEEHEKIFESGKNYIMKLAGASEVAIERNRDNIPQKAMSAAISAGLIAVPLEELIDLEEEIKRLEEEREKVLKEIERAQSLLNNENFVKKAPEKVVNAEREKLEKYTAMLKNIEERLSLLNS
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_CALS4
Sequence: MDIEIIRKTDPEIAEVILKELNRQRNKIELIASENFVSRAVMEAMGTPLTNKYAEGYPGRRYYGGCEYVDMAEELARERLKKLFGAEHANVQPHSGAQANMAAYFALLKPGDTVLGMDLAHGGHLTHGSKVNFSGQIYNFVSYGVREDTGYIDYDQVEDLAKKHKPKLIVAGASAYPRIIDFKKFREIADKVGAYLMVDMAHIAGLVAAGLHPNPVPYADVVTTTTHKTLRGPRGGAILCKQEHAKAIDKALFPGTQGGPLMHIIAAKAVCFKEALSDEFKEYQKRIVENAKALANALMERGINLVSGGTDNHLMLLDLRNTGITGKELETRLDEVNITCNKNAIPFDPLGPNVTSGVRLGTPAVTTRGMKPEDMVEIADIIANMIKDENYKEKAKERVAKLLEKYPLYPDLL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUB1_RHIL3
Sequence: MTSIAHERFHAVAEEPAYARENAPAVSRSAPAAISLTGLEKSFGGNRVLRGINLHIPAGQFVAVIGKSGCGKSTLLRILMGLDEPSAGELHFEDADGAQASPNARIVFQEPRLLPWLSVADNVVVGLGDGVDSRAAAKAAEAVLAEVQLGEKTEEWPARLSGGQRQRVALARALISRPGVLALDEPLGALDALTRISMQELINRVWRELGFTAVLVTHDVSEAVHLADRVIVLDEGRIALDLPIPHPRPRRHGHPGLCELEGRLLAAILGTDGGH
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: E1A_ADE12
Sequence: MRTEMTPLVLSYQEADDILEHLVDNFFNEVPSDDDLYVPSLYELYDLDVESAGEDNNEQAVNEFFPESLILAASEGLFLPEPPVLSPVCEPIGGECMPQLHPEDMDLLCYEMGFPCSDSEDEQDENGMAHVSASAAAAAADREREEFQLDHPELPGHNCKSCEHHRNSTGNTDLMCSLCYLRAYNMFIYSPVSDNEPEPNSTLDGDERPSPPKLGSAVPEGVIKPVPQRVTGRRRCAVESILDLIQEEEREQTVPVDLSVKRPRCN
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E1A protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1 by direct competition for the same binding site on RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes and of the E2 region of the adenoviral genome.  Release of E2F1 leads to the ARF-mediated inhibition of MDM2 and causes TP53/p53 to accumulate because it is not targeted for degradation by MDM2-mediated ubiquitination anymore.  This increase in TP53, in turn, would arrest the cell proliferation and direct its death but this effect is counteracted by the viral protein E1B-55K.  Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection.  Interaction with RBX1 and CUL1 inhibits ubiquitination of the proteins targeted by SCF(FBXW7) ubiquitin ligase complex, and may be linked to unregulated host cell proliferation.  The tumorigenesis-restraining activity of E1A may be related to the disruption of the host CtBP-CtIP complex through the CtBP binding motif.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).  Promotes the sumoylation of host ZBED1/hDREF with SUMO1 (By similarity).
What are the official names of this protein?
Early E1A protein, Early E1A 29.5 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1A protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: ETFD_BOVIN
Sequence: MQVLLARLACPVYQCFHAIKIKKNYLPLCATRWSSTSVVPRITTHYTVYPRDQDKRWEGVNMERFAEEADVVIVGAGPAGLSAAARLKQLAAQHEKDIRVCLVEKAAQIGAHTLSGACLDPRALQELFPDWKEKGAPLNTPVTEDRFGILTEKYRIPVPILPGLPMNNHGNYIVRLGHLVSWMGEQAEALGVEVYPGYAAAEVLFHEDGSVKGIATNDVGIQKDGAPKTTFERGLELHAKVTIFAEGCHGHLAKQLYRKFDLRANCEPQTYGIGLKELWVIDEKKWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLVALGFVVGLDYQNPYLSPFREFQRWKHHPSIQPTLEGGKRIAYGARALNEGGLQCIPKLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGILAAESIFNQLTNENLQSKTIGLDVTEYEDNLKKSWVWKELYAVRNIRPSCHSILGVYGGMIYTGIFYWIFRGMEPWTLKHKGSDSDKLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLKDDSVPVNRNLSIYDGPEQRFCPAGVYEFVPVEQGDGFRLQINAQNCVHCKTCDIKDPSQNINWVVPEGGGGPAYNGM
What is the function of this protein?
Accepts electrons from ETF and reduces ubiquinone.
What are the official names of this protein?
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial, ETF-QO, ETF-ubiquinone oxidoreductase, Electron-transferring-flavoprotein dehydrogenase, ETF dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the ETF-QO/FixC family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: YAP1_RAT
Sequence: MEPAQQPPPQPAPQGPAPPSVSPAGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAGTLTASGVVSGPAATPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHNDQTTTWQDPRKAMLSQLNVPTSASPAVPQTLMNSASGPLPDGWEQAMTQDGEVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGSSNQQQQIQLQQLQMEKERLRLKQQELFRQELALRSQLPSLEQDGGTQNAVSSPGMTQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSIPRTPDDFLNSVDEMDTGDTISQSTLPSQQSRFPDYLEALPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSEILDVESVLAATKLDKESFLTWL
What is the function of this protein?
Attenuates p73-mediated cell death signaling in transcriptional repression-induced atypical death (TRIAD) of neurons.
What are the official names of this protein?
Transcriptional coactivator YAP1, Yes-associated protein 1, Protein yorkie homolog, Yes-associated protein YAP65 homolog.
What is the protein family that this protein belongs to?
Belongs to the YAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Both phosphorylation and cell density can regulate its subcellular localization (By similarity). Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus (By similarity). At low density, predominantly nuclear and is translocated to the cytoplasm at high density. PTPN14 induces translocation from the nucleus to the cytoplasm (By similarity). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity).
Protein: ST7_COLGU
Sequence: MAEAATGFLEQLKSCIVWSWTYLWTVWFFIVLFLVYILRVPLKINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAMSDIFCSAEFRDWNCKSIFMRVEDELEIPPAPQSQHFQN
What are the official names of this protein?
Suppressor of tumorigenicity 7 protein.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LCL2_PARBD
Sequence: MFHILIGALLGLLFLATETRAQFQFFEQMFGGGGHQQQQDHREQNVASDSSWYQRNYDNAHCSDYLCPGTLACVSVPHHCPCQHPDVEDKFELGDGSAICISKGGFKANEAARKVELARKGLL
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: PA2GC_HUMAN
Sequence: MKVIAILTLLLFCSPTHSSFWQFQRRVKHITGRSAFFSYYGYGCYCGLGDKGIPVDDTDRHSPSSPSPYEKLKEFSCQPVLNSYQFHIVNGAVVCGCTLGPGASCHCRLKACECDKQSVHCFKESLPTYEKNFKQFSSQPRCGRHKPWC
What is the function of this protein?
Inactive phospholipase.
What are the official names of this protein?
Putative inactive group IIC secretory phospholipase A2, Phosphatidylcholine 2-acylhydrolase-like protein GIIC.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted.