PharMolix/UniProtQA huggingface dataset:
Protein: OARD1_HUMAN
Sequence: MASSLNEDPEGSRITYVKGDLFACPKTDSLAHCISEDCRMGAGIAVLFKKKFGGVQELLNQQKKSGEVAVLKRDGRYIYYLITKKRASHKPTYENLQKSLEAMKSHCLKNGVTDLSMPRIGCGLDRLQWENVSAMIEEVFEATDIKITVYTL
What is the function of this protein?
ADP-ribose glycohydrolase that hydrolyzes ADP-ribose and acts on different substrates, such as proteins ADP-ribosylated on glutamate and O-acetyl-ADP-D-ribose (PubMed:23481255, PubMed:23474714, PubMed:21849506).  Specifically acts as a glutamate mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to glutamate residues on proteins (PubMed:23481255, PubMed:23474714).  Does not act on poly-ADP-ribosylated proteins: the poly-ADP-ribose chain of poly-ADP-ribosylated glutamate residues must by hydrolyzed into mono-ADP-ribosylated glutamate by PARG to become a substrate for OARD1 (PubMed:23481255).  Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins (PubMed:21849506).  Catalyzes the deacylation of O-acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP-ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively (PubMed:21849506).
What are the official names of this protein?
ADP-ribose glycohydrolase OARD1, O-acetyl-ADP-ribose deacetylase 1, Terminal ADP-ribose protein glycohydrolase 1, [Protein ADP-ribosylglutamate] hydrolase OARD1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus. Chromosome. Note=Localizes both in the nucleoplasm and in the nucleolus (PubMed:29712969). Relocalizes to the nucleoplasm in response to DNA damage (PubMed:29712969). Recruited to DNA lesion regions following DNA damage (PubMed:23481255).
Protein: APOC4_NEOSC
Sequence: MLPPGLSPQALPSLCFCILVLACVVACQQAVPTESPSPQPELASGFWSLVPDNMKALVTRTRDKWQWFWGPEAVQGFVQTYYDDHLKDLSLRSQAWLKSSKDSLLNRAHNLCPRLLCGDGDQN
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ICP27_HCMVA
Sequence: MELHSRGRHDAPSLSSLSERERRARRARRFCLDYEPVPRKFRRERSPTSPSTRNGAAASEHHLAEDTVGAASHHHRPCVPARRPRYSKDDDTEGDPDHYPPPLPPSSRHALGGTGGHIIMGTAGFRGGHRASSSFKRRVAASASVPLNPHYGKSYDNDDGEPHHHGGDSTHLRRRVPSCPTTFGSSHPSSANNHHGSSAGPQQQQMLALIDDELDAMDEDELQQLSRLIEKKKRARLQRGAASSGTSPSSTSPVYDLQRYTAESLRLAPYPADLKVPTAFPQDHQPRGRILLSHDELMHTDYLLHIRQQFDWLEEPLLRKLVVEKIFAVYNAPNLHTLLAIIDETLSYMKYHHLHGLPVNPHDPYLETVGGMRQLLFNKLNNLDLGCILDHQDGWGDHCSTLKRLVKKPGQMSAWLRDDVCDLQKRPPETFSQPMHRAMAYVCSFSRVAVSLRRRALQVTGTPQFFDQFDTNNAMGTYRCGAVSDLILGALQCHECQNEMCELRIQRALAPYRFMIAYCPFDEQSLLDLTVFAGTTTTTASNHATAGGQQRGGDQIHPTDEQYANMESRTDPATLTAYDKKDREGSHRHPSPMIAAAPPAQPPSQPQQHYSEGELEEDEDSDDASSQDLVRATDRHGDTVVYKTTAVPPSPPAPLAGVRSHRGELNLMTPSPSHGGSPPQVPHKQPIIPVQSANGNHSTTATQQQQPPPPPPPPPVPQEDDSVVMRCQTPDYEDMLCYSDDMDD
What is the function of this protein?
Immediate early (EI) protein that plays many roles during productive infection including regulation of host cell cycle progression, regulation of viral gene expression or nuclear export of intronless viral RNAs.  Acts as a transcriptional transactivator via interaction with the cellular transcription elongation factor SUPT6H (PubMed:22171252).  In addition, acts as a post-transcriptional transactivator that mediates the nuclear export of unspliced mRNAs via interaction with DDX39B, a component of the cellular mRNA export machinery (PubMed:16478985, PubMed:26178996).
What are the official names of this protein?
mRNA export factor ICP27 homolog.
What is the protein family that this protein belongs to?
Belongs to the HHV-1 ICP27 protein family.
What are the subcellular locations of this protein?
Virion tegument. Virion. Host nucleus. Host cytoplasm. Note=Shuttles between host nucleus and cytoplasm.
Protein: EIF3C_DROAN
Sequence: MSRFFANGSDSESESSEEEVQATNFNKASAFQFSDDEEEVKRVVRSTKEKRYENLTNIIKTIRNHKKIKDIPNTLSSFEDLTKAYTKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRKNLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAPDQESEAEDEEAAQDSDGGDAGDDSDAGIKREPAEAAPKVAKTVPAKAAPADDDDSDDSIDWDSDSETETESSDDENQYQNMRERFLKRTTEKEEKDDDKRKDKRKEQKIKIRKRPEDDEDGEWETVVKGHVVEKPKMFEKDAEIDIPLVLAKLVEIMSARGKKRTDRRLQIDLLFELRDISDQHNLGTAVSVKIHFNIISAIFDYNQKISEPMKLEHWALLLEVMQSMLKLLLVNPDIHMSESVAEEHEELATSPFYVRGCPLAAVERLDDEFTKLLKECDPHSNDYVSRLKDEVNVVKTIELVLQYFENDGNNNERCRIYLRKIEHLYYKFDPEVLKKKRGEIPQNTQTSVDVMDRLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQENIKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVREMLTKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPVQKVHSIISKMIINEELMASLDDPTETVVMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQDGNWGGQLRDIKRIRGQRIQRGRKHQQQQQQQVQTIDEE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_WOLTR
Sequence: MHKILVRSNYKPLVGQIKINGSKNAILPIMAASLLSSSSVVLHNVPDLIDVHLMSELLEGLGAKVNFMHNKDHKANHTLETDCSNINNYAIQYETASKLRASFLMLGPMLSRFGKARTAFPGGCNIGKRPVDMHIKALEEMGAKIEIDGYNIIATVKGKLQGRKITLEKISVGATENIIMAATLAEGVTTINNAATEPEILDLIEFLKKIGADIKINNTKVIITGVKKLNGCIHKIISDRIEAGTYALAAIITNGKLVLEGINLSDIRCIANELEAIGAMVELYDGSIVISRKNGSIKSTNVATDPYPNFPSDMQPQLMSAMCIADGISVIEENIFENRFSHADELRKLGANISIKKNKAAINGIKSLSGANLYATDLRSTAALVLASLVASGETTINNSHHLWRGYEAMHEKLNSCGADISISP
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHC_ECOBW
Sequence: MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEKTTRNALQLLHFWNAEIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRKPLGIPAFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTPNAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLSTLPQLNRTGKMLHALFSHYRSGSMQSGLRMHDLCAIAWLVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCLGKPANVQVALDLDVKGFQQWVAEVLALAS
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: Y1064_HAEIN
Sequence: MKKLNMEILSERWIIATFSFQGRQYNTKKTSQILPALFAVICAAFAGYFILIGSGMFTEPSVALILLATITILLLSSSKKSFYFILLPLTLLHAFYTPTGLNFGPPSYQYIASLFATDILETKEFLLQIPVSSYLIAFAIPILIFLQYKSAVKFGIKFYRNKTFIALATLLFAYNMPLAEPLKETVSSTLKIVDEVQKLKQISQSDNWGKSTLENSRYDDYVIVLGESARKDYHHAYGYPIENTPFMSNAKGTLIDGFRSAGTNTVASLRLMLTFPDKEKWEPNYSLSLVDLIKSAGIKTYWLSNHGMIGKFDTPVSSLASKSDETFFLKKGGSFNSTNFSDFDLLPKFAQVLENSVQGKRFIVLHIYGSHPMACDRIEDYPKIFDDKDLNPRYGYLNCYVSSIKKTDEFLKRVYDQLEENVKKNHRTFSMIYFSDHGLCHQQDEKTIYFCSIKTVSAESTIIFRYSKFHQMIWNAKNIRCLNQV
What are the official names of this protein?
Putative phosphoethanolamine transferase HI_1064.
What is the protein family that this protein belongs to?
Belongs to the phosphoethanolamine transferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YD003_YEAST
Sequence: MTCGIENSYKSAEKKKKYRSFRFFESRDYSELCIIVGTYY
What are the official names of this protein?
Uncharacterized protein YDR003W-A.
Protein: CE120_MOUSE
Sequence: MVPKSDQLLIVVSILEGRHFPKRPKHLLVVEAKFDGEQLATDPVDHTDQPEFATELAWEIDRKVLHQHRLQRTPIKLQCFALDPQTSAKETVGYIVLDLRTAQETKQAPKWYQLLSNKYTKFKAEVQISLTLETDTKAQVDSYKAKAAPPRDGKVLASLAGVDPKDIVAVLNEEGGYHQIGPAEHCTDPFILSVTIAFATQLEQLIPCTMKLPERQPEFFFYYSLLGNDVTNEPFSDLINPNFEPERASVRIRSSVEILRVYLALHSKLQIHLCCGDQSLGSTEIPLNGLLKKGSTEINQHPVTVEGAFTLDPPNRAKQKLAPVPLDLAPTVGVSVALQREGIDSQSLIELKTQNGHEAEHSQKRVLTPIKEKTLTGPKSPRESPAPPPPPNQTPPTKDDATESEVESLQYDKDPKPTVKGIGSVPASLAQPEATCGASEVVTSGQKIAVPAASHHFCFSVDLRSVHDLELSFPVNCILRYSYPFFGSAAPIMTNPPVEVRKNMEVFLPQSYCAFDFATMPHQLQDTFLRIPLLVELWHKDKMSKDLLLGVARIQLSNILSSEKTRFLGANGEQCWRQTYSESVPVIAAQGSNNRILDLSYTMTLEDYGLVKMREIFVSESSQGVPAVDQKPSSPPPAPCPSEIQMEPRETLEYKAALELEMWKEMQEDIFESQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYSILEGKLQKALTELETREQQLASAEAELQRERKELQLERERNLQELQDSVRRARDDCVYQVELERLKLKQLEEDKQRLQQQLNDAGNKYKTLEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKETVRTEQQELLDIRNELNRLRQQEQNQYQDCKEIASGKLGSPRGSGLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREVLTKNSAS
What is the function of this protein?
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome.  Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development.  Also implicated in the migration and selfrenewal of neural progenitors.  Required for centriole duplication and maturation during mitosis and subsequent ciliogenesis.  Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner (By similarity).
What are the official names of this protein?
Centrosomal protein of 120 kDa, Cep120, Coiled-coil domain-containing protein 100.
What is the protein family that this protein belongs to?
Belongs to the CEP120 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo.
Protein: CB24_ARATH
Sequence: MATSAIQHSSFAGQTTLKPSNDLLRKIGASNGGGRIIMRRTVKSTPQSIWYGPDRPKYLGPFSENTPSYLTGEYPGDYGWDTAGLSADPETFAKNRELEVIHSRWAMLGALGCTFPEILSKNGVKFGEAVWFKAGSQIFSEGGLDYLGNPNLIHAQSILAIWACQVVLMGFIEGYRIGGGPLGEGLDPLYPGGAFDPLNLAEDPEAFSELKVKELKNGRLAMFSMFGFFVQAIVTGKGPIENLFDHIADPVANNAWAYATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated (By similarity).  Mediates rapid phosphorylation and migration of LHCII-PSII to photosystem I (PSI) after transition to state 2 (red) light conditions, thus leading to the formation of PSI-PSII-LHCII and PSI-LHCII supercomplex to balance the relative excitation of PSI and PSII (PubMed:23995216, PubMed:23888908, PubMed:25194026, PubMed:26392145).  Involved in the production of reactive oxygen species (ROS) and stomatal closure upon abscisic acid (ABA) treatment.  Required to prevent water loss (By similarity).
What are the official names of this protein?
Chlorophyll a-b binding protein 2.4, chloroplastic, Photosystem II light harvesting complex gene 2.4, Protein LIGHT-HARVESTING CHLOROPHYLL B-BINDING 2.4.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KDGA_SULAC
Sequence: MEIISPIITPFDKQGKVNVDALKTHAKNLLEKGIDAIFVNGTTGLGPALSKDEKRQNLNALYDVTHKLIFQVGSLNLNDVMELVKFSNEMDILGVSSHSPYYFPRLPEKFLAKYYEEIARISSHSLYIYNYPAATGYDIPPSILKSLPVKGIKDTNQDLAHSLEYKLNLPGVKVYNGSNTLIYYSLLSLDGVVASFTNFIPEVIVKQRDLIKQGKLDDALRLQELINRLADILRKYGSISAIYVLVNEFQGYDVGYPRPPIFPLTDEEALSLKREIEPLKRKIQELVH
What is the function of this protein?
Involved in the degradation of glucose and galactose via the Entner-Doudoroff pathway.  Catalyzes the reversible cleavage of 2-keto-3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively.  It is also able to catalyze the reversible cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3-deoxygalactonate (KDGal).
What are the official names of this protein?
2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. KDPG aldolase subfamily.
Protein: RK2_HORVU
Sequence: MAKHLYKTPIPSTRKGTVDRQVKSNPRNNLIHGRHRCGKGRNSRGIITARHRGGGHKRLYRKIDFRRNQKDISGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTKVPISMGNALPLTDMPLGTAMHNIEITRGRGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLVSQNCLATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGKAPIGRKKPTTPWGYPALGRRTRKRKKYSDSFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GCSH_BORA1
Sequence: MSLPTDRKYTTSHEWVKAEGDVFVVGITENAQDQLGDLVFVGDVSVGANLKAGETAGVVESVKAASDIYAPVDGVIVAFNDELEANPNLINESAFTAWIFKIKPLNAADADKLLDAAGYEAVANG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: Y641_ALIF1
Sequence: MNSIWKQYIDILQGVVKPALGCTEPICAAYAASVATQMLGSKPETIDVFVSDNLYKNSMGVFVPRTGRVGLAIAAATGAIGGNPDAGLEVLAKITEEEVDEAQKLIDNGCVVVQRETTDEFIYCRVIAKNAVHNAEVTISGGHTLIIEKRLDDNVIFTLDSSLPKTSTASICDGVDITISSIYDFATQAEFDDIKFILEAKELNIALAQEGLNNPYGLEVGRTYQKNIEKGLLAKSLDSDILIYTSAASDARMGGATLPAMSNYGSGNQGIAATIPVVKMADFFNADDEKLARAFIMSHLGAIYIKSHYPPLSAFCGNAVTSAAASMAMVYLAGGTFEQSCSAIQNTISDTSGMICDGAKSTCAMKVGSSAQSAMKSALLALNDHCVTKQGVIADDVEKTIKNIGRMITTGMPNIDHEIIEIMAS
What are the official names of this protein?
UPF0597 protein VF_0641.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: YMI9_YEAST
Sequence: MPHAWQSCIFDSFSRFVELFLAYNKQRLYFRSSPLLTAEFLRLTNEMQERTKSGAAPNARVLIGQALGAETRCALQFPHDKAKTVSFPRIIHTSITNPWIKLSLVRPYYTFLFSCMLYKIDP
What are the official names of this protein?
Putative uncharacterized protein YML089C.
Protein: ACCD_PINTH
Sequence: MSIKEWFEDKRKITALLKNSVERDSKDANETEKNKNKSIDYAKIKKLWAQCDNCENLLYLRFLRENQSVCKECGYYLQMNSSDRIELLIDRDTWRPMDEDMYTLDVLQFYSENEPSHSDNLNSEDESYKDHITFYQIETGLTDAIQTGIGQLNGLTIALGVMDFQFMGGSMGSVVGEKITRLIERATAESLPLIMVCASGGARMQEGSFSLMQMAKIASALYIHQKEKKLLYISILTSPTTGGVTASFGMLGDIIIAEPKAYIAFAGKRVIEQTLGQKVIEDFQVTEHLFGHGLFDLIVPRNLLKGVLSELFWFYVLRSSL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: HIS4_LISMF
Sequence: MQIFPAIDLKNGQCVRLFQGDFSKKTVVNEDPIAQAKAFATDGATYLHIVDLDGALEGRPINLEIIQRMKKAAKIPVQVGGGIRSMAQVDYYLESGIDRVIIGSAALTNPDFLRAAVQKYGAKIVAGIDAKNGFVATRGWLDVSQVSYLDLAKRMEKVGVETIIYTDISRDGTLTGPNLEQMANLKEHVKVSLIASGGVSSRADLEALAQLGLYGAIAGKALYNHDISMSDIVEVEQIAY
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_BATNI
Sequence: YLVSPAAYAALGAYMFLLILIGFPVNFLTLYVTLEHKKLRTPLNYILLNLAVADLFMVLGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGEIALWSLVVLAIERWIVVCKPISKFRFTEDNAIMGLAFSWVMALACAVPPLVGWLRYIPEGMQCTCGVDYYTRAEGFDNESFVIYMFIVHFLIPLSVIFFCYGRLLCAVKEAAAAQQESETTQRAEKEVSRMVVIMVIGFLVCWLPYASVAWWIFCNQGSDFGPIFMTLPSFFAKRPAIYNPMIYICMNKQFRHCMI
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: ERPA_HAES1
Sequence: MADLAVPLTFTDAAANKVKTLISEEENTELKLRVYITGGGCSGFQYGFTFDEKTNDGDLIVENSGVKLVVDPMSLQYLVGGTVDYTEGLEGSRFIVNNPNASTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: TILS_TREPS
Sequence: MSESRQKLHPLLVHVARSFGHFLVPRKPSCLLVAVSGGADSLALLYAAHELAPDFGVCACAVTVDHSLRAQEGALDARFVRALCARFSPPLPCFVQQISAGAVHACAKIRGRGVQDAARALRYKVFDHVAARCGAQVVLTAHTRDDQYETLLMRLFQGAAASALQGIRAARGRYVRPLLKVSRTCVEDFLQTRGVRWREDASNTCRKYVRNRIRHELIPALDAVLAGWRSGLDKTFAGISAEHSFCVAALTRWREGCSHAWEPVPRALGTRLRMPRSDFLAAEFILRFFLLQEACVRLGVSHRVPRGALERCARFDGVRRIHVSGLQLERAGAYVLFSCIHASDTARETKKQDAGSPPSSEKQGVSAIYVARPGAYPCACGTLLVEVRPAGVFVCCAQDHVGVGPFSFPFYIRTHRTGDTISIRGGHKGIRKMFSEWHVPLSDRTVLPMIEQDGVLRALYGAALGYQNRYAERTPHE
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSB_XYLF2
Sequence: MRNWRWLLLVLAALLAWLQHRFWFGPGNSGEVRMLQVQIVQQHQENERLRQRNASLAAEVKNLKDGDAAIEERARSELGMIKPGEIFYRVVEDIPVPLPNDTSADHGVDLSQPRREKR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: XPT_BACFR
Sequence: MQLLKKRILQDGKCYEGGILKVDSFINHQMDPVLMKSIGVEFVRLFAGTNVNKIMTIEASGIAPAIMTGYLMDLPVVFAKKKSPRTIQNALSTTVHSFTKDRDYEVVISSDFLTPKDNVLFVDDFLAYGNAALGVIDLIKQSGANLVGMGFIIEKAFQNGRKTLEERGVRVESLAIIEDLSNCRITIKD
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPA_ECOLX
Sequence: MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKERTRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITEKTNQNFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: NIG2A_ODOIS
Sequence: MFTLKKSMLLLFFLGTINLSLCQEERDAEEERRDEDNAKMEEIKRGIFSTVFKAGKGIVCGLTGLC
What is the function of this protein?
Has antimicrobial activity against Gram-negative bacterium E. coli ATCC 8739 (MIC=25 ug), against Gram positive bacteria S. aureus ATCC 6538 (MIC=3. 1 ug), methicillin-resistant S. aureus ATCC 43300 (MIC=12. 5 ug), B. subtilis ATCC 6633 (MIC=12. 5 ug) and against fungus C. albicans ATCC 90028 (MIC=50 ug).
What are the official names of this protein?
Nigrocin-2ISa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GYRB_NEIGO
Sequence: MTEQKHEEYGADSIQVLEGLEAVPKRPGMYIGDTQDGSGLHHMVFEVLDNAIDEALAGHCDKITVTIHADHSVSVADNGRGMPTGIHPKEGRSAAEVIMTVLHAGGKFDNNSYKISGGLHGVGVSVVNALSDWVTLTIYRDGKEHFVRFVRGETEEPLKIVGDSDKKGTTVRFLAGTETFGNIEYSFDILAKRIRELSFLNNGVDIELTDERDGKHESFALSGGVAGFVQYMNRKKTPLHEKIFYAFGEKDGMSVECAMQWNDSYQESVQCFTNNIPQRDGGTHLTALRQVMTRTINSYIEANEVAKKAKVETAGDDMREGLTCVLSVKLPDPKFSSQTKDKLVSGEIGPVVNEVINQALTDFLEENPNEAKIITGKIVDAARARQAARKAREITRRKGLMDGLGLPGKLADCQEKDPALSELYLVEGNSAGGSAMQGRDRKFQAILPLKGKILNVEKARFEKMLASQEVATLITALGAGIGKEEFNPEKLRYHRIIIMTDADVDGAHIRTLLLTFFYRQMPDLVERGYIYIAQPPLYKAKYGKQERYLKDELEKDQWLLGLALEKAKIVSDGRTIEGAELADTAKQFLLAKTVIEQESRFVDELVLRAMLHASPIDLTSSENADKAVAELSGLLDEKEAALERIEGHEGHQFIKITRKLHGNVMVSYIEPKFLNSKAYQTLTQTAAALKGLVGEGAKLYKGENEYDADSFETALDILMSVAQKGMSIQRYKGLGEMNPEQLWETTMDPTVRRLLKVRIEDRIADEVFVTLMGDEVEPRRAFIENNALIAQNIDA
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
Antibiotic resistant DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_MYCBP
Sequence: MNRLDFVDKPSLRDDIPAFNPGDTINVHVKVIEGAKERLQVFKGVVIRRQGGGIRETFTVRKESYGVGVERTFPVHSPNIDHIEVVTRGDVRRAKLYYLRELRGKKAKIKEKR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.