PharMolix/UniProtQA huggingface dataset:
Protein: MDE6_SCHPO
Sequence: MERKELSYTIQSWSSYSGAFHPINILIDNPHQANSRWSCNTSICKPNNSEEQYVILKLDKLALVTDITFGKFHTPHLCNLKDFIVYGGREQHLMFPLLRAGLTNDSNRETFPLCIKKYNKIENSIACKYIKIVPLQAHAHEFNMSIWYVALHGIDSASALSCTEKNRALHLEKKALNCLLSYFAFKGKLDICSVILQSYQLSIPHSPLMRMYDAFCRLGDTQKTILLFQQELQAEIIEKWPKHKLTKLRSHRIATFLKGISRRSGHQMVYNPKDNCIYLYGGWDGVKTFSDFWIYNVDKDLWIMENEYGIPGERVCHRMVIDTSQQKLYLLGNYFGSSRETEVPPDARTDFWEFDISKKVWTCLSYDTSKDGGPAAIFDHGMSVDEKRGIVYVSGGCKWDPDELVFEGLYAYDTKNRIWEQLAVRYEDRQKHCEFKIERMGHCMEYFPDENKLYIFGGQSYDQEFILDMCYIKLETREAVQHVRKNDTSQSPSPSFCQRSIMDSKNHRIFTMFGFEQRNIHKVLRPSLWIFYITTEEWVKISDINEEEGNEHPCSRFGHAVAADLNRNIIYLMGGNASTHPLRPMKLSDFWKLDILDRWGIKHCLSNVSLQLHLHRFHELVSENLAKAVEYLQKSMQPQFDKSPLFWNALILDAFSGTHKNKDIAQRRFETFQTIYDLLPVDENTVAPNESLLNMIEFFT
What are the official names of this protein?
Mei4-dependent protein 6.
Protein: KAIB_PROMP
Sequence: MVARKTYILKLYVAGNTPNSMRALNTLKEILENEFKGVYALKVIDVLKQPQLAEEDKILATPTLAKILPPPVRRIIGDLSDREKVLIGLDLLFDELSESEYSGGTKN
What is the function of this protein?
May be a metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, and perhaps clock output effectors.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: TENA_STAAN
Sequence: MEFSQKLYQAAKPIINDIYEDDFIQKMLSGDIGADALRHYLKADAAYLKEFTNLYALLIPKMNSMNDVKFLVEQIEFMVEGEVLAHDILAQIVGESYEEIIKTKVWPPSGDHYIKHMYFQAHSRENAIYTIAAMAPCPYIYAELAKRSQSDHKLNREKDTAKWFDFYSTEMDDIINVFEALMNKLAESMSDKELEQVKQVFLESCIHERRFFNMAMTLEQWEFGGKVND
What is the function of this protein?
Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.  Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).  Is also able to catalyze the hydrolytic cleavage of thiamine; however, this thiaminase activity may not be physiologically relevant.  Therefore, is probably involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment, rather than in thiamine degradation.
What are the official names of this protein?
Aminopyrimidine aminohydrolase, Thiaminase II.
What is the protein family that this protein belongs to?
Belongs to the TenA family.
Protein: RLMH_CLOB8
Sequence: MNITIITVGKIKEKYLRDAIEEYSKRLGRYCKLDIVELVDEKTPDNASEKEEEVIKEKEGQGILNKIKDNMFVIAMDLGGKQLTSEEFAGYIDNLGVTGNPNIAFIIGGSLGISKSVLARANYKLCFSKMTFPHQLFRVMLLEQIYRGFRIIKGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_DICNV
Sequence: MPRRTAFFISDRTGITVESMGDALLNQFEVNLKRENHPFIDSPEKAHQLVNIINATAEKSALRPLVFSSIVDEEIRNIVKSSAGLHLSFFDAFLGTLEKELGVSALQFSPRINSIINTERYDARMESLNFTLNHDDGSSDRNLQHAEVILIGVSRSGKTPTCLYLALQYGIRAANYPLTPEDLQSPNLPNMVKPFRNKLFGLTIDPERLSKIRQERRPNSEYADILTCKREVSDAKAMFYRFNLPYANTTHKSVEELAVHIMQTCHLKRRY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: Y3424_BRUAB
Sequence: MNARLTGLGLNLLSFAVGIGGWYLLTATGAVVLPGPVDVLERAVTLLLNGQLVGDIFASLRRVLSGFVLGVALAIPVGFLMGWYRIARSLIEPWVQFFRMIPPLAVIPLAIVTLGIDESPKIFVIFLASFLSSVVATYQGVISVDRTLINAARVLGAKDATIFARVIVPASVPFILVGVRIGLGSAWATVVAAELIAAQSGLGYRMQQAQLYYDLPTIFVSLVTIGILGLFMDRLLQAADRRLTQWQERA
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Probable ABC transporter permease protein BruAb2_1124.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMH_STRP1
Sequence: MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTPDKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYSTITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RANB3_HUMAN
Sequence: MADLANEEKPAIAPPVFVFQKDKGQKSPAEQKNLSDSGEEPRGEAEAPHHGTGHPESAGEHALEPPAPAGASASTPPPPAPEAQLPPFPRELAGRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST
What is the function of this protein?
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein.  Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction.  In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex.  Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1.  Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner.  Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
What are the official names of this protein?
Ran-binding protein 3, RanBP3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RLP23_ARATH
Sequence: MSKALLHLHFLSLFLLCCVCHSSIFTLNFHFTGIVACRPHQIQAFTKFTNEFDTRGCNNSDTFNGVWCDNSTGAVAVLQLRKCLSGTLKSNSSLFGFHQLRYVDLQNNNLTSSSLPSGFGNLKRLEGLFLSSNGFLGQVPSSFSNLTMLAQLDLSYNKLTGSFPLVRGLRKLIVLDLSYNHFSGTLNPNSSLFELHQLRYLNLAFNNFSSSLPSKFGNLHRLENLILSSNGFSGQVPSTISNLTRLTKLYLDQNKLTSSFPLVQNLTNLYELDLSYNKFFGVIPSSLLTLPFLAHLALRENNLAGSVEVSNSSTSSRLEIMYLGSNHFEGQILEPISKLINLKHLDLSFLNTSYPIDLKLFSSLKSLRSLDLSGNSISSASLSSDSYIPLTLEMLTLRHCDINEFPNILKTLKELVYIDISNNRMKGKIPEWLWSLPLLQSVTLGNNYFTGFQGSAEILVNSSVLLLYLDSNNFEGALPDLPLSIKGFGVASNSFTSEIPLSICNRSSLAAIDLSYNNFTGPIPPCLRNLELVYLRNNNLEGSIPDALCDGASLRTLDVSHNRLTGKLPRSFVNCSSLKFLSVINNRIEDTFPFWLKALPNLQVLTLRSNRFYGPISPPHQGPLGFPELRIFEISDNKFTGSLPPNYFVNWKASSRTMNQDGGLYMVYEEKLFDEGGYGYTDALDLQYKGLHMEQAKALTSYAAIDFSGNRLEGQIPESIGLLKALIAVNISNNAFTGHIPLSMANLENLESLDMSRNQLSGTIPNGLGSISFLAYINVSHNQLTGEIPQGTQITGQSKSSFEGNAGLCGLPLKESCFGTGAPPMYHQKQEDKEEEEEEEEEEEEVLNGRAVAIGYGSGLLLGLAIAQVIASYKPEWLVKIIGLNKRRKR
What is the function of this protein?
Involved in the perception of necrosis and ethylene-inducing peptide 1-like proteins (NLPs), that act as extracellular signals mediating immune activation.  Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity.
What are the official names of this protein?
Receptor like protein 23, AtRLP23.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SIX1_BUTOC
Sequence: VRDAYIAQNYNCVYFCMKDDYCNDLCTKNGASSGYCQWAGKYGNACWCYALPDNVPIRIPGKCHS
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This contractive toxin is highly toxic to insects and barely toxic to mammals.
What are the official names of this protein?
Alpha-insect toxin BotIT1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CC157_MOUSE
Sequence: MAHLLGSQACMDSLRKDLTDLQGTIVDVFSRAGPVRFPSWKFPDRVACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCASYLENLSVEQMMPPARAAGPCMSVGLTVRRFWSNLLRLGLLYQQAVPQKRANQGEISITKPTAKGEPARSPECMTAKFIKPPSPVPGLPLICQGLQSIPVRVSLRSPGGTSEKTKSVYSQTVETALVPCDACTSVQGSLWEVGKVVISLCQSQNLPSSLGQFQKLVKDSLGLKPLPAATVGHWAAEQSKDLTRLNKHVGALTQLVGPLRAQLEDAEGQKDGLRKQVSKLEQALQQEQGQRQRQTEEAERTLAKCEHDRHQLLTETCDLKTKVAVLEGDLKQQQKSIQAMEAKAQQLEEEGERRAAAERQVQQLEEQVQLLAGRLDGASQQIRWASTELDKEKARVDSMVRHQESLQAKQRTLLQQLDCLDQEREELRGSLDEAEAQRSELEEQLQSLQSDREQEQCQLQAQQELLQSLQQEKQDLEQVTTDLQLTISELRQQLEELKERERLLVAFPDLHQPEEAQIQSSSNVTQDMERQVQANAIRIQVLQEENKRLQSMLTKIREVAQQGGLKMVPQGQLWSPPYKGIQGATPPAQAQSAFSGLTGRRQSPGSRTSSTGRTHPGGLRTSPSRQPGGLPSKFSLGDGSHSASCTQNPIRALARLRRKLSPNRQAGSTYQPQERPT
What are the official names of this protein?
Coiled-coil domain-containing protein 157.
Protein: TULP_DROVI
Sequence: MHPQLHKCRQLMDAYIRQKRASPGMVQASDLQMSRPMSGMRGNSRELHAYDGPMQFIGSPHNPDQILSNNSSSVHLSSSMNSSRNNSNNLRSLSTINQEDLIEEISSHELEDEESSPVTVVENPLPPLSANSAHSQRLRNGQQSFNETLDEDDYANRNIAGVAPVRPAGIASPYKDGVAPEASNGVANGSNSGVGSAESEGDVIGSIDLFVMQPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKKIFLLGGRKRKKSKTSNYIVSCDPTDLSRNADGFCGKLRSNVFGTSFTVFDSGNKDSTESPRLDLAVIIYDTNILGFKGPRNMTVILPGMTEDDQRVKISSADPKQQGILDLWKMKNMDNIVELHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLVHDSDPEYIVMQFGRTSEDVFTMDYRYPLCAMQAFAIALSSFDGKIACE
What are the official names of this protein?
Protein king tubby.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSTB_BURP1
Sequence: MNMAESHLDPSKLATGPAGFGAAAGQRPLAPLNAKIEVKNLNFFYNQFHALKNINLSIPEGKVTAFIGPSGCGKSTLLRTFNKMYALYPEQRAEGEIVMDGENLLQSKLDISLLRARIGMVFQKPTPFPMSIYDNIAFGVKMFERLTRSEMDDRVEWALTKAALWNEVKDKLSQSGYGLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELIAELKSDYTVVIVTHNMQQAARCSDYTAYMYLGELIEFGETEKIFIKPARKETEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HEM3_PROM1
Sequence: MTLDQLRIASRRSQLAMVQTNWVRDELQRAHPDLAITIEAMATQGDKILDVALAKIGDKGLFTKELEAQMLLGHAEIAVHSLKDLPTNLPEGLILGCITEREDPSDALVVNEKNQIHKLETLPEGSVVGTSSLRRLAQLRYHYPHLVFKDVRGNVITRLEKLDSGEYDCLILAAAGLQRLGFANRIHQLIPTDISLHAVGQGALGIECVSGQQKVLDILKTLEHESTSKRCLAERSFLRELEGGCQVPIGVRTEINNNELILEGMVASLDGKRLIRDIKKGSVSSAEEIGIDLANELKGRGAGEILEEIFKSARA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RPOB_PSEMY
Sequence: MAYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQQGVSKEQFRDIGLHAAFKSVFPIISYSGNAALEYVGYRLGEPAFDVKECVLRGVTFAVPLRVKVRLIIFDKESSNKAIKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDAVFVRIDRRRKLPASVLLRALGYSTEEVLDAFYDTNVFHVKNESLSLELVPQRLRGEVAVLDIKDASGKVIVEQGRRITARHINQLDKAGIKELEVPLDYVIGRTTAKAIVHPATGEIIAECNTELTADLLAKMAKANVVRFETLYTNDIDCGPFISDTLKIDSTTNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSAERYDLSAVGRMKFNRRIGRTEIEGSGVLSKEDIVAVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAVKERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVKEGKVTDEIVFLSAIEEADHVIAQASATLNDKGELVDELVAVRHLNEFTVKAPEDVTLMDVSPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVCVVARRGGVIDSVDASRIVVRVNDDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGDQVARGDIMADGPSTDMGELALGQNMRVAFMPWNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEISSDIPNVGEAALNKLDEAGIVYVGAEVGPGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDSRALAIEKQQLDEIRKDLNEEFRIVEGATFERLRSALVGAIAEGGAGLKKGTAITDEFLDGLERGQWFKLRMADDALNEQLEKAQAYISDRRQMLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIRRRIQPGDKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDIVLNPLGVPSRMNVGQILETHLGLAAKGLGEKINRMLEEQRKVAELRKFLAEIYNEIGGRQENLDEFSDNEILELAKNLKGGVPMATAVFDGAKETEIKAMLKLADLPESGQMRLFDGRTGNQFERPTTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLIKEIRSLGIDIDLETE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: NIFH_FRAAL
Sequence: MRQIAFYGKGGIGKSTTQQNTMAAMAEMGQRVMIVGCDPKADSTRLILHSKAQTSVIQLAAEKGSVEDLELDEVLVEGQWGIKCVESGGPEPGVGCAGRGVITSITYLEEAGAYENLDFVTYDVLGDVVCGGFAMPIRQGKAQEIYIVTSGEMMAMYAANNIARGILKYAHSGGVRLGGLICNSRKTDREDELIMELARRLNTQMIHFIPRNNVVQHAELRRMTVIEYDPKNSQADEYRQLANKIVNNDMKTIPTPITMDELEELLIDFGIMAQEDESVIGKAAAVA
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: ISPH_NEIMB
Sequence: MNEKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVHNKFVVDNLREKGAVFIEDLAEVPPGATLVYSAHGVSKAVRQEAAERGFRVFDATCPLVTKVHKEVARLDAQDCEIIMIGHKGHVEVEGTMGQLAPGKMLLVETVGDVAKLEVRNPDKLAYVSQTTLSVDETKDIIAALNARFPNIRNPHKEDICYATTNRQTAVKELAEQCDIVIVVGSPNSSNSNRLREVAASRGIDAYMVDNAGYLQRAWFEGKNKVGVTAGASAPEVLVREVLATIRGWGHETVREGEGAEESIVFVLPKELRREGETKPDLCKR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: FGFP1_RAT
Sequence: MRIHGLILLSFLLLAAQVLSEKVRKTAKNVPDSTTEEDMSPSLGKARNKQRSRTSKSMTHGRFVTKDQATCRWAVTEEELGINLKVQCTRADQEFSCVFAGDPTGCLKYDKDQTYWKQVARTLRKQKNICENSKSVLKTRVCRKKFPESNLKVVNPRKEKAEVSPREHNKVQEAVSMEPNKVKVDITTSPAATVAVKDSECLEDPDVLTQRKTALEFCGESWSSFCTFFLNMLQATSC
What is the function of this protein?
Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs.  Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth (By similarity).
What are the official names of this protein?
Fibroblast growth factor-binding protein 1, FGF-BP, FGF-BP1, FGF-binding protein 1, FGFBP-1, Growth factor-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the fibroblast growth factor-binding protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cell membrane; Peripheral membrane protein. Note=Extracellular and plasma membrane- associated.
Protein: OBG_LACPL
Sequence: MFVDQVKVDVKAGNGGNGMVAFRREKFVPNGGPAGGDGGRGGSVVLQADEGLRTLMDFRYTRKFKAAAGGNGMIKQMTGRSAKDTIIKVPLGTTVTDAETGELIGDIVNKDQRLVVAKGGRGGRGNIHFASAKNPAPEIAENGEPGDELTIRMELKVLADVGLVGFPSVGKSTLLSVVTSAKPKIAAYHFTTLVPNLGMVRLDDGRDFVMADLPGLIEGAANGVGLGIQFLRHIERTRVILHLIDMSGVEENDPFEDYHKINHELTSYDPDLLKRPQIVVATKMDMPDAEANLEDFKAKLATDDTLPNTPAVYPVSSITQQGLKALLAKTADLLDTTPQFPIKGVDDLKHRDYTTEADADFSIDNPEPGLFVLSGDKLERLFKMTNLDHEESLMRFARQLRGMGVDDALRAAGAKNDDTIQILDYSFQFMD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCA10_CHICK
Sequence: MMDVSSWKEMEVALVSFDNADQIVEDPCYSNDLSPASQSRKGHPSCANLLSNWRILINSENANNETIFSRFSAEFSEHLVGERVGMEEGDQRVIINIAGLRFETRLKTLNQFPETLLGDPEKRMRYFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDVFADEITFYELGDEAMDQFREDEGFIKDPETLLPTNDFHRQFWLLFEYPESSSAARGVALVSVLVIVISIIIFCMETLPEFREEREYKSTQELSKNTTDTLLAHSTFTDPFFVIETACIIWFSFELFVRFIVCPSKTEFFKNIMNIIDIVSIIPYFVTLTTELIQQSELNGQQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPQSHFSSIPDGFWWAVVTMTTVGYGDMCPTTLGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKQILPGEVERILNSVVTGNDSMESLNKTNGGYPRDKAKK
What is the function of this protein?
Mediates voltage-dependent potassium ion permeability of excitable membranes.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.  The channel activity is up-regulated by cAMP (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily A member 10.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.8/KCNA10 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACYP_THEMA
Sequence: MKALKIRVEGIVQGVGFRYFTRRVAKSLGVKGYVMNMDDGSVFIHAEGDENALRRFLNEVAKGPPAAVVTNVSVEETTPEGYEDFTIKYY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: HA21_MOUSE
Sequence: MATIGALVLRFFFIAVLMSSQKSWAIKEEHTIIQAEFYLLPDKRGEFMFDFDGDEIFHVDIEKSETIWRLEEFAKFASFEAQGALANIAVDKANLDVMKERSNNTPDANVAPEVTVLSRSPVNLGEPNILICFIDKFSPPVVNVTWLRNGRPVTEGVSETVFLPRDDHLFRKFHYLTFLPSTDDFYDCEVDHWGLEEPLRKTWEFEEKTLLPETKENVMCALGLFVGLVGIVVGIILIMKGIKKRNVVERRQGAL
What are the official names of this protein?
H-2 class II histocompatibility antigen, E-D alpha chain, H2-IE-alpha.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CEMA_SOLTU
Sequence: MAKKKAFTPLFYLASIVFLPWWISFSVNKCLESWVTNWWNTGQSQIVLNNIQEKSLLEKFRELEELLFLDEMIKEYSETHLEEFGIGIHKETIQLITIQNENRMDTILHFSTNIIWFGILSGYSILGKEKLVILNSWAQEFLYNLSDTAKALCLLLVTEFFLGYHSPPGWEFAIRSIYNEVGVVANEQTITILVCILPVIFDTCFKYWLFRYLTSLSPSILLIYDSITE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: ARGC_PROM1
Sequence: MAKSTSKTGRIAIIGASGYGGLQLVKLINEHPNFEISTLNGERSVGKNWNEINPFMKILQDKKITKSNIDEIALDSDYAILSLPNGLSSQLTPLLLKKGVKVLDLSADYRFKSLDKWKEVYTKEAAKYKRYDYELCEEAIYGFSEEFSSEISKSRLIACPGCYPTASLSLLIPFLKQGLIESEGIIVDAKSGTSGGGRNPNEQLLLSECSESISPYGVIGHRHTAEIERIASHFAGHEVNLQFTPHLVPMVRGILSTVYARLRDPGLTAEDCKIVIEAFYKDQPFIDILPVGIYPATKWVKNTNKVMISVEVDKRNGRIVLMSVIDNLLKGQAGQAVQNLNIMHGLESDIGLPKITFYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_LACJO
Sequence: MSFSVTLPDGSKKDFDKAVSVKELASSIATSLGKAAVGAKINGVMKPLDYIVDEDVEAAIITDKDEEGLDILRATAAFLLEAVAKRKYPELRLGMHEADEGGFFVDTDKEDQIKVTELPDLEKAMQKAIKNGEKIEYTSMKKSELEEIFKDDQFKLDLLKDEEDEVAVYKLGDFVDFGFDALLPNTGKIKNFKLLSVAGAYWLGKSSNPMLQRIFGTAFFKKAALDEDLKRRAEIKERDHRTIGRDLDLFFVDPKVGAGLPYWMPKGATIRRVVERYIVDKEVADGYEHVYTPVLMNVDAYKTSGHWAHYRDDMFPPMDMGDGEMLELRPMNCPSHIQIYKHHIRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVALDQIREEFAKVLKLIMDVYKDFDITDYYFRLSYRDPKNTDKYYANDEMWETSQSMLKAAMDDLGLDYVEAEGEAAFYGPKLDIQTKTALGNDETMSTIQLDFMLPERFGLTYVGQDGEEHRPVMIHRGIVGTMERFIAYLTEIYKGAFPTWLAPVQAEIIPVNEEAHGEYADKVRAELAKRGFRAEVDHRNEKLGYKIRESQTQKVPYTLVLGDEEMNANGVNVRRYGTEEQISKSLDDFIAEIDADVKSYSREK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB6_ORYSJ
Sequence: MREILHIQGGQCGNQIGSKFWEVVCDEHGIDPTGRYAGTSDLQLERVNVYYNEASCGRFVPRAVLMDLEPGTMDSVRTGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPRGLSMASTFVGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEAEYEEEEDAIQE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-6 chain, Beta-6-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.