PharMolix/UniProtQA huggingface dataset:
Protein: Y2851_MYCTU
Sequence: MTEALRRVWAKDLDARALYELLKLRVEVFVVEQACPYPELDGRDLLAETRHFWLETPDGEVTCTLRLMEEHAGGEKVFRIGRLCTKRDARGQGHSNRLLCAALAEVGDYPCRIDAQAYLTAMYAQHGFVRDGDEFLDDGIPHVPMLRPGSGQVERP
What are the official names of this protein?
UPF0039 protein Rv2851c.
What is the protein family that this protein belongs to?
Belongs to the UPF0039 (ElaA) family.
Protein: TRMD_STRP3
Sequence: MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKARHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEELIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSHQDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLLERYDFSEEERKLLDKIKEALGQGED
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGT_QUERO
Sequence: MGSEALVHVFLVSFPGQGHVNPLLRLGKRLAAKGLLVTFSTPESIGKQMRKASNITDEPAPVGEGFIRFEFFEDGWDEDEPRRQDLDQYLPQLELIGKDIIPKMIRKNAEMGRPVSCLINNPFIPWVSDVAESLGLPSAMLWVQSCACFCAYYHYYHGLVPFPSEAEPFIDIQLPCMPLLKYDETPSFLYPTTPYPFLRRAILGQYGNLDKPFCILMDTFQELEHEVIEFMSKICPIKTVGPLFKNPKAPNSVRGDFMKADDCLEWLDSKPPQSVVYISFGSVVYLTQKQVDEIAFGLLQSGVSFLWVMKPPHKDAGLELLVLPDGFLEKAGDNGRVVQWSPQEQVLAHPSVACFVTHCGWNSTMESLTSGMPVVAFPQWGDQVTDAVYLVDVFKTGVRMCRGEAENRVITRDEVEKCLLEATVGPKAVEMKQNASKWKAAAEAAFSEGGSSDRNIQAFVDEVRARSVAITGKSTANGVALDLAEKSAEINGKVDLVETKTNGKVELVEA
What is the function of this protein?
Glucosyltransferase that catalyzes the formation of 1-O-beta-D-glucose esters with hydroxybenzoic acids as preferred glucosyl acceptors.  Has the highest activity with 3,4-dihydroxybenzoate, vanillate and gallate in vitro.  Gallate is the predicted native substrate of the enzyme, which thus catalyzes the formation of 1-O-galloyl-beta-D-glucose, the first committed step of gallotannin biosynthesis.
What are the official names of this protein?
Gallate 1-beta-glucosyltransferase, UDP-glucose:gallate glucosyltransferase, Vanillate 1-beta-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: ECLH_MANSE
Sequence: MAGKVTVAFFMFAMIAFLANFGYVECNPAIATGYDPMEICIENCAQCKKMLGAWFEGPLCAESCIKFKGKLIPECEDFASIAPFLNKL
What is the function of this protein?
Neuropeptide that triggers the performance of ecdysis behaviors at the end of a molt.  It triggers adult behavior patterns: larval, pupal and adult ecdysis, and plasticization during the molt.
What are the official names of this protein?
Eclosion hormone, EH, Ecdysis activator.
What is the protein family that this protein belongs to?
Belongs to the insect eclosion hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: RMD1_RAT
Sequence: MALSSRLWRLLPLLRGAEQSVCQLARSWGSGGRCGTWGFRGSEVTGNTRAFKRGLLFSALSYLGFETYQVISQAAVVHATAKVEEILEQADYLYESGETEKLYQLLTQYKESEDVELLWRLARASRDIAQLCKTSEEEKKVLLYEALEYAKRALEKKGSSFAAHKWYAICISDVGDYEGIKVKIANAYVIKEHFEKAIELNPKDATSIHLMGIWCYTFAEMPWYQRRIAEVLFANPPSSTYEEALKYFHRAEEVDPNFYSKNLLLLGKTYLKLNNKKLAAFWLVKAKSYPAHTEEDKQIQTEAAQLLTGL
What are the official names of this protein?
Regulator of microtubule dynamics protein 1, RMD-1, Protein FAM82B.
What is the protein family that this protein belongs to?
Belongs to the RMDN family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.
Protein: RL21_LEGPL
Sequence: MYAVIKTGGKQYTVKEGDVLKIEMLPENVGNEIKFSEVLMLVDGDKVTCGAPFVAKATVKAEVLDHGRHKKVKIIKFRRRKHHMKQMGHRQYYSQVKITAIGK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RS21_LISW6
Sequence: MSKTVVRKNESLEDALRRFKRTVSKSGTLQESRKREFYEKPSVKRKKKSEAARKRKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: H18_BOVIN
Sequence: MAPGSIASSDTSSSTSSSSTSSASSASAEGSSRPLGSEKPGLARGAVRAPRRHPPVLRMVLEALQAGERRRGTSVAAIKVYILQKYPTVDALRLNHLLKQALATGLHRGLLIRPVNSKAKGATGSFKLVPKDKRKIPPRKTAPRMPGQAEGKDPKKPSESKKDPANTVEVKKGSRKPREERAAPSKPGAAKKAPKKGTQTKDPEPRLGEAKKSSRRPDKAAQAPPSAGGPGGKSKVKERGSRQADTKAHRKTQPGSQSSKSTVTKGENGAPLAKKKMGGKVPKEAAGEGPKAKAPVPPKGAGSKKEPGPLAGKAEASKGPRKPGIPTKSSVSKAASKKAEAEG
What is the function of this protein?
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure.  Essential for meiotic maturation of germinal vesicle-stage oocytes.  The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte.  The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure.  The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity).
What are the official names of this protein?
Histone H1.8, Histone H1oo, Oocyte-specific histone H1, Oocyte-specific linker histone H1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome. Note=In the 1-, 2- and 4-cell embryo, it is uniformly spread within the cytoplasm, while it is concentrated onto the chromatin in the nucleus. In the 8- to 16-cell embryo, its presence diminishes in the cytoplasm, although it is still strongly expressed in the nucleus.
Protein: MYBPP_RAT
Sequence: MKKANDRQSPPKLLEKKRAKAPEQPTPPIQEEPEPVSNVLQGDDILALAIKKEDLTKQHIPQFEETGEKPVVTQKFIIRKLKPKDSCKRVYHLVAHPANPDATTKPLDYSGPRDSFLSSDQILPHQILGSLQDFKRIAVARGNTQLAKLINIQPCLMTLISAKEEPKPKSPKEEKRPPWAPPLQHNFLKNWRRHITLRKKQQEVLSEHLKKPASELLMNSGEGYRKIQEEREAIDRALPTQHDRKAMNCFWSPLEYLGDEKSGLLMTKKKKQRGLVEPITHIRKPFSIQMETGLPVQKDAWYRYTWDRSLFLIYRRKGLQNIMAELDFSQQDIDGLEVVGHGKPFSSVTVEEPLPLEKSQKSSSEDTVFLDSLTNLSDMVPMPILGPSLLFCGKPACWIRGSNPEDKKNIGIGVRLTFETLEGEKTSSELTVVNNGTVAIWYDWRRRPQQDFFQDLKQNRTQRFYFNNREGVILPGETKHFTFFFKSRNAGIFMESWEFGTHPTLLGGAALQITLHAISLTQDIFMDERKLLESKLAAHEAVTIAQSVLQDLLRGVSTPERAPSPVDAYLTEEDLFHYRNPRLHYQHRVVQNLHQLWQQYTEAKASQEEALNLRTPTVPLLFVEKPPDHSRTLASEYPQLQPHQEMDTLKDPKNSLLPQKTGISTKSMQRKSIMEEILVEEGPDRENTRSPRVLENLPPPKWNLCLEDFRQAVMTFPEELQREDALIQLNKAAMELCQEQKPLQSDLLYQMCLQLWRDVIDSLVSQSLWLRSLLGLPEKETVYLDIPDEGQKSPPVTEVKVTSGKLGKEDRRGGAQEKKQLSARDKEEKKGSKTPSKEDRLNSKKQKAKDDKKVVKSTSRDRLLSEDPPADSSATSQEPIDPLVMEKYTQRLYSEVYGLLDNLVIDMMVLADELGSEKNVEEPLRFCT
What is the function of this protein?
May play a role in spermatogenesis (By similarity).  May be involved in synaptic processes.
What are the official names of this protein?
MYCBP-associated protein, Organ of Corti membrane-associated protein of 106 kDa.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Colocalizes with MYCBP in the cytoplasm.
Protein: MEP_ASPFC
Sequence: MRGLLLAGALALPASVFAHPAHQSYGLNRRTVDLNAFRLKSLAKYVNATETVIEAPSSFAPFKPQSYVEVATQHVKMIAPDATFRVVDDHYVGDNGVAHVHFRQTANGLDIDNADFNVNVGKDGKVFSYGNSFYTGQIPSSAALTKRDFSDPVTALKGTTNTLQLPITVDSASSESTEEKESYVFKGVSGTVSDPKAKLVYFVKDDGTLALAWRVETDIDSNWLLTYIDAKSGEEIHGVVDYVAEADYQVYAWGINDPTEGERTVIKDPWDSVASEFTWISDGSTNYTTSRGNNGIAQSNPSGGSSYLNNYRPSSSSLSFKYPYSVSSSPPSSYIDASIIQLFYTANIYHDLLYTLGFTEKAGNFEYNTNGQGGLGNDYVILNAQDGSGTNNANFATPPDGQPGRMRMYVWTESTPYRDGSFEAGIVIHEYTHGLSNRLTGGPANSNCLNALESGGMGEGWSDFMATAIRLKPGDKRSTDYTMGEWASNRAGGIRQYPYSTSLSTNPLTYTSVNSLNAVHAIGTVWASMLYEVLWNLIDKHGKNDAPKPTLRDGVPTDGKYLAMKLVMDGMALQPCNPNFVQARDAILDADTALTGGENQCEIWTAFAKRGLGAGAKYSSRNRVGSTEVPSGVC
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates and probably acts as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase mep, Elastinolytic metalloproteinase mep, Fungalysin mep.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMM_ACIC5
Sequence: MPTSPWVTLAHIVRPQGRRGEVIAELLTDFPEKFAERRHVFLTRDAASDAAPREMELAGYRLAQNRVVLHFAGIDSIDAAEMLRGLDVVIPESERAPLDQDAAYISDLIGCDVWDEAAGQRVGIVQDVDRQASHVDLLVVDCENGQRAEIPFVKAFLVKLDTTGKRITMRLPEGLLEINASTATAREPRARRTRKRGLRKPITGADATPPDSQ
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EV45_EHV4
Sequence: MSGDPTASLKDYQLLELDTAAGNDQAPQLPTKTVLGFTPPLPTLPQPTELVYTKRRRPKRRSRCRCLCFTMGMFAMGVLMTTTLLVSTFVLTVPMVALRTAPCPAQTFGLGDECVRPVSLDAYNSSNSSEIGAVCGAYSEMPAPDNTTVLIMNLLDCLNIGINESAGEKLNLTDTPLANCNFSQNSVCSRKRVGVCYAARPLSPLGELIYKARQALRLDHILPFLQ
What are the official names of this protein?
Envelope protein UL45 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae HHV-1 UL45 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein.
Protein: MOAA_SYNJB
Sequence: MPTVNYLRISLIDRCNFRCQYCMPDEAELTWLQAPERLTDEEILTLVREVFLPLGIDCFRLTGGEPLLRPGLEHLIRALCSLPGVRDVALTTNGFNLSQKAQLLYEAGLRRINISFDSLNPETFRLITGRDRWRQVWAGIQVAHQVGFDPLKLNVVVIPGLNESEVEDLAALTLERQWHVRFIEFMPIGNAALFQQAGWVESEVLRQRIRARFGLEPGFVAGNGPADVFRIPGAKGTLGFISQMSECFCDRCNRMRLSSDGWLRPCLLNESGQINLRDPLRAGIPAERLRQQVRELLDIKPDINFKGRDTGSQGSYRRTMSQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: EDIL3_HUMAN
Sequence: MKRSVAVWLLVGLSLGVPQFGKGDICDPNPCENGGICLPGLADGSFSCECPDGFTDPNCSSVVEVASDEEEPTSAGPCTPNPCHNGGTCEISEAYRGDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCTEEE
What is the function of this protein?
Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor.  Inhibits formation of vascular-like structures.  May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.
What are the official names of this protein?
EGF-like repeat and discoidin I-like domain-containing protein 3, Developmentally-regulated endothelial cell locus 1 protein, Integrin-binding protein DEL1.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21_MYCGA
Sequence: MPKIEVKDGDLELALRKFKRVASETKRSFLKHEYHLRKGVKRREKEKAARKRLQKKHRMY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: URM1_ASHGO
Sequence: MVQVQVEFLGGLDVIFSKQRKHQVSVEGANGSVTVGDLIDYIVSNMIQKQKDVSVFLEDNTIRPGILTLINDTDWELEGEKEYVLEDGDIVSFTSTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPC_XANCB
Sequence: MSTSLPLRDDGAVRASFALALFVLLGLGLGYSLVATGITSALMPDQAHGSLLRADGRVIGSSLVAQPFADARYFQPRPSAAKYDPTAAAGSNQARSNPELLARIATARAEIAQRDGIAPDAVPGELLTQSGSGLDPHLSPAGAQVQLRRVAAARGWPEQRVAALLQAATEQPQFGLLGQPRINVLALNLALDRAGDGVPGTENGVEQQR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SYDND_CHLTB
Sequence: MKYRTHKCNELSLDHVGEHVRLSGWVHRYRNHGGVVFIDLRDRFGITQIVCRQEENPELHQLMDQVRSEWVLCVEGLVCARLEGMENPNLVTGSIEVEVSSLEVLSRAQNLPFSISDEHINVNEELRLTYRYLDMRRGDILDRLMCRHKVMLACRQYLDEQGFTEVVTPILGKSTPEGARDYLVPSRIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADRQPEFTQIDMEMSFGGPEDLFPVVEELVTRLFAVKGIELKAPFLRMTYQEAKDSYGTDKPDLRFGLRLKNCCEYARKFTFSIFLDQLAHGGTVKGFCVPGGADMSRKQLDIYTDFVKRYGSMGLVWIKKQDGGVSSNVAKFASEDVFQEMFEAFEAKDQDILLLIAAPEAVANQALDHLRRLIAKERQLYDSTQYNFVWITDFPLFAKEEGELCPEHHPFTAPLDEDISLLDSDPFAVRSSSYDLVLNGYEIASGSQRIHNPDLQNKIFALLKLSQESVKEKFGFFIDALSFGTPPHLGIALGLDRIMMVLTGAETIREVIAFPKTQKAGDLMMSAPSEILPIQLKELGLKL
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_RUEST
Sequence: MRLSRYFLPVLKETPSEAQVVSHRYMLRAGMIKQSAAGIYSWLPLGYRVLKKIEGIVHEEQMRAGHIPMLMPTIQSADLWRESGRYDAYGEEMLRIRDRHDRDMLFTPTAEELITDIFRANVSSYKDLPLTMYQIQWKFRDEIRPRFGVMRGREFYMKDGYNFDLTKEDALHAYNRHLVTYLRTYERMGLQAIPMRADGGPIGGDYTHEFLVLAETGESEVFYDSEITDLTFGAREIDYDNVEQCQAVLEEFTSRYARTDETHDEALFNAVPEERRRVARGIEVGQIFYFGTKYSEALGATVQTADGQSVPVHMGSHGIGVSRLLGAIIEASHDDKGIIWPEGVTPFHCGIVNLKQGDDEADAACEQLYAALTAIGLEPLYDDRKERAGGKFASMDLIGLPWRITVGPRGLKNGVVEVTSRRTGESEEMSPEDAVKKIAAIYANHPTPRGF
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_HAEI8
Sequence: MSLTNEQIIEAIASKTVTEIVELIAAMEEKFGVSAAAAVAAAPAAGGAAAAEEKTEFDVVLKSAGANKVAVIKAVRGATGLGLKEAKDLVESAPANLKEGVSKEEAEALKKELEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RS3_AMBME
Sequence: MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGSKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLAWDPSGKIGPKKPLPDHVSIVEPKDEILPTTPISEQKGGKPDPQVPQQPPQQPPAMPPPVPTA
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Has endonuclease activity and plays a role in repair of damaged DNA.  Also involved in other processes including regulation of transcription, translation of its cognate mRNA, spindle formation and chromosome movement during mitosis, and apoptosis.
What are the official names of this protein?
40S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleolus. Mitochondrion inner membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, spindle.
Protein: TAT_SIVS4
Sequence: METPLKEQENSLESCREHSSSISEVDVPTPESANLEACYNKCYCKRCCYHCQHCFLKKGLGICYEQHRRRTPKKTKANPFPASNNRSLSTRARNRQPKKEKKETVETEVAADLGLGR
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: PROC_RABIT
Sequence: IPDDVGYRNQKTASKEGVCVVSKCQDGPNTLPRAKRANSFLEELRPSSLERECVEEVCDLEEAKEIFQSVDDTLAFWYKYVDGDQCAALPSEHPCSSQCCGHGTCADSIGGFSCQCHGGWEGSFCQYEVRFSNCSVDNGGCAHYCLEEEAGRSCSCAPGYELADDHLQCEPAVRFPCGRLGWKRIEKKRGNVKRDLEQVDEMDEVDPRLIDGKLTRRGDSPWQVILLDSKKKLACGAVLIHVSWVLTAAHCMEEPKKLFVRLGEYDLRRKERWELDLNIQEVLIHPNYSRSTTDNDIALLRLAQPATLSQTIVPICLPDNGLAERELMQAGQETVVTGWGYHSSREKEAKRNRTFILNFITVPVAPQNECEQVMSNIISENMLCAGILGDRRDACDGDSGGPMVASFRGTWFLVGLVSWGEGCGDLNNYGVYTKVSRYLDWIHSHIEEKEAAPESPAP
What is the function of this protein?
Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.  Exerts a protective effect on the endothelial cell barrier function.
What are the official names of this protein?
Vitamin K-dependent protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Endoplasmic reticulum.
Protein: RL2_SALEP
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLVEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: COAX_EHRCJ
Sequence: MLIAIDVGNTNIKFAICTSNRILKIIRIASQQAKTADQYFFYLNNIINQLNTDFKNINNIIISSVVPSITKPMLELSKNYFNINPIILDNNHADIFNIKINLQNKALGSDRLADIIAASNIYPNKDLLIIGMGTATVFNLLNKDKCIYGQVIAPGAHILAKSMRQFTALLPEVSVSKQDKVVHNNIYHAMESGVYWGYITMVNGMIEKIIKEEKKDLHVIATGGNSYLFFDHKTAINNIETDLTIKGILYLHNMLSNNTAQNSI
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_LEVBA
Sequence: MADVKYKRIMLKLSGEALAGDKGFGINPPVIKTVAEEVKDVYNLGIQIAIVVGGGNMWRGEAGAQMGMERAQADYIGMLATIMNALALQDNLESIGVPTRVQTSIEMRQIAEPYIRRKAIRHLEKERVVIFAGGTGSPYFSTDTTAALRAAEINADAILMAKNGVDGIYSADPKKDPAAVKFDQLTQLDIINKGLNVMDTTASSLSMDNDIPFVVFNLNESGNIRKVVEGENIGTTVRGK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP283_YEAST
Sequence: MMPAKLQLDVLRTLQSSARHGTQTLKNSNFLERFHKDRIVFCLPFFPALFFVPVQKVLQHLCLRFTQVAPYFIIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKIFQISYRVPMIWLDVFQVFFVFLVISQHSLHS
What are the official names of this protein?
UPF0479 membrane protein YPL283W-B.
What is the protein family that this protein belongs to?
Belongs to the UPF0479 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SOMA_HETFO
Sequence: MARVLVVLSVVVASLFFSQGATFENQRLFNNAVIRVQHLHQLAAKMMDDFEEALLPEERKQLSKIFPLSFCNSDSIEAPAGKDETQKSSVLKLLHTSYRLIESWEFPSKNLGNPNHISEKLADLKMGIGVLIEGCVDGQTSLDENDAFAPPFEDFYQTLSEGNLKKSFRLLSCFKKDMHKVETYLSVAKCRRSLDSNCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TILS_DESVH
Sequence: MERTIKGVCDGENGEGVRNCHCVVALSGGADSTALLLILHYLRQRLGLSLSALHVDHGLRPESAAEARAAVTFCHALGIPLAVHTLTVDELAAVWRVGTEEAGRKARYDLLAAALPSPAADWICTGHHLGDLAEDVLMRLVRGCGWPALGGMRLCDPARRILRPLLLTEKDRLEAFLATLGVSWTEDPSNASDTYLRNRMRHGVIPLLTAENPGFLDQVRDLWQLAHIDADFWETRTAATLSAAPASPSHVEGEASAPHDAAHGAESIRLPKTTLTGLHQAERLRLFKEVLRRMGEGQARAETLLALDAAWVAGRGGTRFMFAGCKTATVRRGDIIFSGGPPAEDTP
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YB230_YEAST
Sequence: MRNELYQLWCVASAARGVAKSSFVRANSAMCEYVRTSNVLSRWTRDRQWEAAKALSQRVKKEYAAN
What are the official names of this protein?
Uncharacterized protein YBR230W-A.