PharMolix/UniProtQA huggingface dataset:
Protein: DEF_THET8
Sequence: MVYPIRLYGDPVLRRKARPVEDFSGIKRLAEDMLETMFEAKGVGLAAPQIGLSQRLFVAVEYADEPEGEEERPLRELVRRVYVVANPVITYREGLVEGTEGCLSLPGLYSEEVPRAERIRVEYQDEEGRGRVLELEGYMARVFQHEIDHLDGILFFERLPKPKREAFLEANRAELVRFQKEARALLKELSQG
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: GLYA_BACAH
Sequence: MVDHLKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRVKEIFGAEHVNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDAESHRINYDDVLAKAKEHKPKLIVAGASAYPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGGMILCEEQFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEDMDEIASLIAYTLKNHENEAALEEARKRVEALTSKFPMYTDL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_GEODF
Sequence: MAKIIDGKAIAAKIRGEITAEVAKLAAQGITPGLAVVLVGEDPASKVYVSMKEKACKDVGIFSDEYKLPAETTEEELLQLIDKLNKDRKIHGILVQLPLPKQINTEKVLEAISPEKDADGFHPYNVGRLVIGKPLFQPCTPYGVMVMLKETGVDLAGKEVVVVGRSNIVGKPVAFMCLQQNATVTLCHSKTRDLAAKVAMADVVIAAVGQPEMIKGAWIKKGAVVIDVGVNRVGEKKLVGDVEYEAASARASAITPVPGGVGPMTITMLLYNTLESAKRR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Y876_CLOP1
Sequence: MLVLTTETIPGKGIKEVKGLVKGSTVRCKNIGKDIASSFKNLVGGEMNSYTEMLTEARQIAIGRMVDEAESLGANAIIGMRLVSSSLAAGAAEMVAYGTAVIYEDA
What are the official names of this protein?
UPF0145 protein CPF_0876.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: YJCS_BACSU
Sequence: MKSHKMMGGGISMHYITACLKIISDKDLNEIMKEFKKLEEETNKEEGCITFHAYPLEPSERKIMLWEIWENEEAVKIHFTKKHTIDVQKQELTEVEWLMKSNVND
What are the official names of this protein?
Uncharacterized protein YjcS.
Protein: HES2_XENLA
Sequence: MAPNVALADSMHNYQPKPGKRNQEASELRKTLKPLMEKRRRARINESLNQLKTLILPLIGKDNSRYSKLEKADILEMTVRFLRDIPPVQAQNQADRYKEGYRACVERLSAILGKSHVLTGEASNRLLEYLQRSPELCSSDCNHPPKPQRPRIVLQVSPRTSQFGSPLQNQPSSHRPAPCPPQLNSSIWRPW
What is the function of this protein?
Transcriptional repressor.  Essential in the retina to govern glial versus neuronal differentiation.  Promotes gliogenesis through the inhibition of neuronal differentiation by at least two distinct mechanisms; represses proneural gene transcription, and also physically interacts with proneural proteins, including neurod1.
What are the official names of this protein?
Transcription factor HES-2, XHes2, Hairy and enhancer of split 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRGP2_MOUSE
Sequence: MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIEMDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIYLNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSKLKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYTENKLKAIKARNEYLLALEATNASVFKYYIHDLSDIIDQCCDLGYHASLNRALRTFLSAELNLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQPVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSMESVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGESQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLIACVTMDNLQERAVHIRKVLLVLPKPTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQAHVNELIKTIIIQHENIFPNPRELEGPIYSRGGSMEDYCDSTHGETTSAEDSTQDVTAEHHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQYIVVQDTEDGVVERSSPKSEIEVMSEPPEEKVTARTGASCPSGGHVADIYLANINKQRKRPESGSIRKAFRSDSHGLGSSLTDSSSLGVGASCRPSSQPIMSQNLPKEGPDKCSISGHGSLNSISRHSSLKNRMDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELQELERQSSAKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSASPQATDKSCTV
What is the function of this protein?
Postsynaptic RAC1 GTPase activating protein (GAP) that plays a key role in neuronal morphogenesis and migration mainly during development of the cerebral cortex (PubMed:19737524, PubMed:22559944, PubMed:27373832).  Regulates excitatory and inhibitory synapse maturation and density in cortical pyramidal neurons (PubMed:19737524, PubMed:22559944, PubMed:27373832).  SRGAP2/SRGAP2A limits excitatory and inhibitory synapse density through its RAC1-specific GTPase activating activity, while it promotes maturation of both excitatory and inhibitory synapses through its ability to bind to the postsynaptic scaffolding protein HOMER1 at excitatory synapses, and the postsynaptic protein GPHN at inhibitory synapses (PubMed:27373832).  Mechanistically, acts by binding and deforming membranes, thereby regulating actin dynamics to regulate cell migration and differentiation (PubMed:19737524, PubMed:22559944, PubMed:26439400).  Promotes cell repulsion and contact inhibition of locomotion: localizes to protrusions with curved edges and controls the duration of RAC1 activity in contact protrusions (PubMed:26439400).  In non-neuronal cells, may also play a role in cell migration by regulating the formation of lamellipodia and filopodia (PubMed:22559944).
What are the official names of this protein?
SLIT-ROBO Rho GTPase-activating protein 2, srGAP2, Formin-binding protein 2, Formin-binding protein 27, FBP-27.
What are the subcellular locations of this protein?
Cell membrane. Cell projection, dendritic spine. Postsynaptic density. Postsynaptic cell membrane. Cell projection, lamellipodium. Cytoplasmic vesicle, phagosome. Nucleus. Cytoplasm, cytosol. Note=Recruited to actin-rich phagosomes during phagocytosis (PubMed:21148482). Translocates from nucleus to cytoplasm during development (By similarity).
Protein: ATPF_RHORU
Sequence: MISLALAAETAEHGGEAASHGGLFADPAFWVSIAFLMVVGFVYIKAKNKILGALDGRGAAVKAKLDEARKLRDDAQALLAEYQRRQRDAMKEADEIIRHAKDEAARLRAKAEADLEASIRRREQQAVDRIAQAEAQALAQVRNEAVDVAVSAARSLMAGSLAKADQNRLIDAAIADLPGKLH
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Single-pass membrane protein.
Protein: FRDD_SALG2
Sequence: MINPNPKRSDEPVFWGLFGAGGMWGAIIAPVIVLLVGIMLPLGLFPGDALSFERVLTFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTAIGVITL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FNR_CAPSP
Sequence: CEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILLLSKKNAEERLDVFIYNLSRRFGQRGFSPREFRLTMTRGDIGNYLGLTVETISR
What is the function of this protein?
It is involved in the activation of genes necessary for anaerobic respiration.
What are the official names of this protein?
Anaerobic regulatory protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I05A1
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVSGIGRFYIQMCTELKLSDHEGRLIQNSITIERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYRRRDGKWVRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVVPRGQLSTRGVQIASNENMEAIDSNTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPIVPSFDMNNEG
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: IRX_CAEEL
Sequence: MIPIANQVKMEEPTTPQTTTPAPPTSAPDALRGILPPNLLGQFHFHPAMAQVLAAQAQAAAAAQQATLAGFPGVPMFPHGIPADLKPEMLLGGGPGPMPMFFSDAHRLYHPYGLDGIKKRNATREATAPLKDWLHSHRKNPYPSKADKVMLAVGTGMTLTQVSTWFANARRRLKKENKMTWSPQNRRGDGCDDDEDDDDDDMNRPSSSTSINSERKGESLFGKPHLASPTPSGGSGGSDELTTPKKELVSPIPNDDSESPKRKPKMWSIADVTSDDDSSKKDSPPSSDENLLTGSLFQNAMKKQMEVMARLDPTLFRHTMHPFMFQLLAQQAAQGQQLALLAPQTTPPNEAGLNSQAETSTPSPASSPTSSPRSHQE
What is the function of this protein?
Transcription factor (By similarity).  Required for D-type inhibitory GABAergic motor neuron synaptic remodeling, acting via degenerin unc-8-dependent and -independent mechanisms (PubMed:22031882, PubMed:34045310).  Regulates expression of genes involved in synaptic remodeling, including negative modulation of immunoglobulin domain-containing protein oig-1 and positive modulation of unc-8 (PubMed:26387713, PubMed:22031882, PubMed:34045310).
What are the official names of this protein?
Putative iroquois-class homeodomain protein irx-1.
What is the protein family that this protein belongs to?
Belongs to the TALE/IRO homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNH2_CHLSY
Sequence: MLPDLSIEHDLQRRGYANLAGIDEAGRGCWAGPVVAAAVVLSPAVYRQPDLLAGVNDSKQLTAGARERIYTSIQTHALGVGVGIVPAFLIDAYGILPATRLAMIQALLALPCAVDALIIDAVQLPGISLPQTALVRGDERSLSIAAASIIAKVTRDRLMATADHCFPHYGFALHKGYGTAVHRRALAQYGPSPLHRRTFQPVIEALLSLEQS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_STRA3
Sequence: MRKKPIIIGVTGGSGGGKTSVSRAILSNFPDQKITMIEHDSYYKDQSHLTFEERVKTNYDHPLAFDTNLMIEQLNELIEGRPVDIPVYDYTKHTRSDRTIRQDPQDVIIVEGILVLEDQRLRDLMDIKLFVDTDDDIRIIRRIKRDMEERDRSLDSIIEQYTEVVKPMYHQFIEPTKRYADIVIPEGVSNIVAIDLINTKVASILNEAK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_ECO57
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RL4_VIBA3
Sequence: MELMVKGADALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRSEVSGGGAKPWRQKGTGRARAGTIRSPIWRTGGVTFAAKPQDHSQKVNKKMYRGAMKSILSELIRQERLIVVDNFSVEAPKTKELVAKLKELELNDVLIVTGEVDENLFLAARNLYKVDARDVAGVDPVSLIAFDKVLMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PMD1_YEAST
Sequence: MTVLQPPSSVCYPLNLPIVPNPNLDEATRKKLTLECRTGAAVELARSGVFVHGGLTLPLNLTIINSLQLQKELILYFGKQKDRNADFKTLADWISPEIFFLDLISRTWQRINTTIDTTSENELNNGLSFKERLFHSMCFTESNIYIFGGLMVSPHNGYELIATNELWKLDLKTKCWSLISENPQITRRFNHSMHVLNENNENQDTKLIIVGGLDNMDIPVKKIDIFNLRTSLWESESKSDENPASKGSSKILVNIDGMPISLSHDSNFSVLIENNQAEIPTLALYYPQREANTSRRGTDDGSFSTYAHDLDDKSKLPKHHHHHHGDLKYFESDDADENAVKTLMSPIVILPLLGNSQGARMTSNPTQNNKENSILQVPFHLQYPSGNYFNYNIVVIGFYPDPQPSNLHCFIYNIASGKWIRVNIACTECSISMHRFWKLLIWKSHHQALLLGTRTDDFCSPSVQKFDHILSFSLPMLNGYNKLVNTKHTRTNNGIANSHNLNVNLSLYDHLPYSNSSTIEHTNPYTVTQGYSLDDSGIPRLTSTATSQFENYSRYITVPLEMESTSSIFPPYAMVLGKDALEIFGKTLSDFEFITADGDSIGVPVYLLRKRWGRYFDSLLSNGYANTSFNYEFNGDTSNIISFSPHTASKTTKFGNSSQSSNGSLEKYFSKNGNSKSNSNTSLKKPHSVDFTSSTSSPKQRAISHNKLSPSEPILCADEEDSRSNTLKQHATGDTGLKETGTSNKRPISTTCSSTGMVFRVPFQDMKNSKLGLSEQSGRSTRASSVSPPPVYKKSTNDGNDSNCTLSNTPLVYRRASTVGTTTNSSVDDGFSSIRRASHPLQSYIIAKSSPSSISKASPAEKAFSRRKSSALRFIASPNQSRQTSFASTASTASVVSSTSGRRRNSNQISHLGSSASLPNSPILPVLNIPLPPQEKIPLEPLPPVPKAPSRRSSSLAEYVQFGRDSPVASRRSSHSTRKSSSSDARRISNSSLLRNTLDSQLLSNSYGSDIPYEASIQEYGMNNGRDEEEDGDNQDYGCISPSNIRPIFSTINAININGNFKEGEFFSSKSYINNEKSRRLSYISNPESVESTNSNNNAIIELEPLLTPRSLYMPWSTASVRAFAEFFYTAQINGKWLLAPVTLDLLIMAKIYEIPILYELITEVLYKIISKKEEGLSVTCEALLNLFQQKVSRYCNENEGKIRKQLDSSESYQDTLEIKRSLANIDNGYVDSYLLRNTSMAQSIHYTDDSNGETEIDMHHTGISSIGSLANRAVPTVFAGGPRDSHNSIGSIAFPSNSGVQNIRRSVSLFSPATKKKSSLSRETDPLDTSDQFTDDVPDSGPVSRQQNFPRRSSSFTETVPTEPTRYNYQNLDSSKSNRASDDKEEQNEQATLQDISNFDKYKVETLQKRNSNDGKDLDRTNDPLKNRGTEIPQNSSNLETDPFIRDSFDSDSGSSFRSDSDDLDSQLGILPFTKMNKKLQEQTSQEFDDSIDPLYKIGSSTPGSSRLHGSFSKYIRPNSQREDGSEYVNISSLENMVSPNALPPVDYVMKSIYRTSVLVNDSNLMTRTKEAIELSKVLKKLKKKVLQDISQMDDEMRETGKPIFARGSSSPTLSRQHSDVATPLKQQENTRPALKFASSSPISEGFRKSSIKFSQAPSTQISPRTSVTDFTASQQRRQHMNKRFSTQTTHSTSALFMNPAFMPSAVNTGRKESEGHCEDRSATANRTNRKEDATTNDNDNIAPFPFFGKRR
What is the function of this protein?
Negatively regulates early sporulation-specific genes.  Seems to exert its function by positively regulating the Ras/cAMP pathway.  Required for growth under alkaline conditions.  Acts synergetically with MDS3.
What are the official names of this protein?
Negative regulator of sporulation PMD1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNP_RICTY
Sequence: MLKYLIKFYPKILFIIEGTLVTLKYSIIAVILGLVIGMLLAICKVNKNCVLRLFANFYTSIFRGTPLLVQLSIIYFAAPYIISIKFSVFMAGVISFALNSGAYVSEVIRAGINTIDKGQFEAAEALAIPKFLIMKDIILPQAINNIFPSLVNELINLIKESAIISMLGEMDLMRRAQIVSIETYNYFFPMLIAACCYYILVMLISFIAKIIEKKMIVN
What is the function of this protein?
Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Putative glutamine transport system permease protein GlnP.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GNAS_CRILO
Sequence: MGCLGDSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPNFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs).  Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP.  GNAS functions downstream of several GPCRs, including beta-adrenergic receptors.  Stimulates the Ras signaling pathway via RAPGEF2.
What are the official names of this protein?
Guanine nucleotide-binding protein G(s) subunit alpha, Adenylate cyclase-stimulating G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(s) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: THIK_ECOHS
Sequence: MPFRSNNPITRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGAVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRPLRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHLQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: MNMG_CAUVN
Sequence: MSKSWDVIVIGGGHAGCEAAAASARAGARTLLLTHKLETIGEMSCNPAIGGLGKGHLVREIDALDGVMGRMADKAGIQFRMLNRSKGPAVRGPRSQIDRRLYREAMQAELFSTGNLDIIAAAAEDLIVEDGKVAGAVDAAGQAYRAPRVILTTGTFLKGVIHRGEDRIPAGRVGDQPAIGLSDRLYGLGFQMGRLKTGTPARLDGKTIAWDRLESQAADDTPVPFSYLNHRIDVPQIACGVTYTTEETHRIIAERIGESLVYSGRATGVGPRYCPSIEDKVVRFADKTSHQIFLEPEGLDDDTVYPNGISTSVSEETQLLFLRTIPGLEQVEVIRYGYAIEYDYVDPRELYPTLETKRLPGLYLAGQINGTTGYEEAGAQGLVAGLNAALAVQGREPAIFARDEAYIGVMIDDLVTRGVTEPYRMFTSRAEFRLTLRADNADQRLSDRGISLGVVGPVRAAAWTEKKARLDAARAFARSVTLTPNEAVKAGFKVNSDGVRRDVFAMLAYPDVTLDDLGRIWPEVFTWNTDVREQIEIEAAYAGYLDRQRADAESLRKDEDLRLPADLDYAEIGSLSNEVRGKLARVRPLTLGQAARIEGVTPGALTALLAHVRRGRAA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMC_FLAPJ
Sequence: MLIKNYRTQFVQALASIFDEKEIESFFYIILEAFHQLKRVDLVLSPDLKLDNIQLLQWETVLLQLKEQKPIQYILGETQFFGLPFYVNENTLIPRPETEELVEWIIKENLKISSLKNLKILDIGTGSGCIAISLAKNLPNASVFAIDVSDKALATAQKNAVLNEVDITFIEKNILQTEDLNQEFDIIVSNPPYVRNLEKKEIHKNVLEYEPHLALFVEDNDSLLFYRKITELATRNLSNNGQLYFEINQYLGKETVELLEKYNFKNTTLKKDIYGNDRMIKVNFR
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: RBFA_TRIEI
Sequence: MAIARRISRIASLIKQEISQMLLHGIKDNRVGIGMVSVTDVDVSGDLQHAKVFVSIYGSDEVRSQTMAGLRSATGYVRSELGKRIRMRRTPEVIFVEDRSLERGTEILSLLNKLSQERQQQEIEDITHKESHQDTIE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_SERMA
Sequence: MSKRWFVTGTDTEVGKSVASSALLQAANRAGYPSAGYKPVASGSEMTAEGLRNGDALALQANSGVALDYDEVNPYVFAEPTSPHIVSADEGRPIDAARLSDGLRRLEQRADWVLVEGAGGWFTPLSAEYTFADWVRQEQLPVILVVGIKLGCINHAVLTAQAVQQAGLTLAGWIANDVGGAPGRRHQEYLATLRRMLPRRCWAKSRTCRRPERAPLGQYLDISLLAQ
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y011_MYCGE
Sequence: MGKIKLKNRKALVVYDNKDDFEKNQTFALSLIKELQKKKLNAEVLLLENKDINFEAKINEAELILNRSRKVDFLKTNNQINTFLVNPFNVVFIANDKYETYKWLKQNRFLTVNSSLLSKETIKSFPVIVKKRNSHGGKDVHLVNSADEIKHLNIENATEWIVQPFLSIGTVEYRAYILFGKIIKVIKKISNANQFKANFSQGAEVSLFKLKWFTKRKIKKIAKRLREGYYAIDFFLNRYNRVIVNEIEDAAGARALVQLCPDLNITKIIIRTIISKFKKFLKKKLIS
What are the official names of this protein?
Uncharacterized protein MG011.