PharMolix/UniProtQA huggingface dataset:
Protein: RK20_VITVI
Sequence: MTRTRRGYIARRRRTKIRLFTSSFRGAHSRLTRTITQQKIRALVSTHRDRDRQKRDFRRLWITRINAVIHENGASYSYSRFIHDLYKRQLLLNRKILAQIAISNRNCLYMISNEIIK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CHLN_TRIV2
Sequence: MTIAQEPTALNFECETGNYHTFCPISCVAWLYQKIEDSFFLVIGTKTCGYFLQNAMGVMIFAEPRYAMAELEEGDISAQLNDYAELKRLCEQIKRDRNPSVIVWIGTCTTEIIKMDLEGLAPKLEGELGIPIVVARANGLDYAFTQGEDTVLAAMAHRCPDKAPVAEAEKNERNAVQKLLNFGKKKELVAQEESEYVDHPPLVLFGSLPDPVVTQLTLELKKQGIKVSGWLPAKRFTELPVLEEGYYVAGVNPFLSRTATTLMRRRKCKLIGAPFPIGPDGTRAWIEKICSVFGITPQGLDEREAQIWAGLEDYVKLIRGKSVFFMGDNLLEVSLARFLVRCGMTVQEVGIPYMDKRYQAAELAMLEKACQEMGVPSPKMVEKPDNYNQVQRIYDLKPDLVITGMAHANPLEARGINTKWSVEFTFAQIHGFTNARDILELVTRPLRRNNNLKDLGWDKLVREEAKI
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: PA2A1_BUNCA
Sequence: MNPAYFLVLAAVCVSLLGAANIPPQPLSFYRYTEMIQCTIRGSLTYLDYMDYGCYCGTGSRGTPVDELDRCCQTHDNCYAEAEEHPKCSSLVKSPYMNLYSYTCSGGTITCNADNDECGAFICNCDRTAALCFAKAPYNEENKEIDISKRCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 1, svPLA2, PA2-I, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSC_SALDC
Sequence: MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: IXTPA_ACIC5
Sequence: MALTLYVASSNAGKLRDFRVAAGHTATEILPLPGLAEIDAPEETGTTFAENARLKAEFYSRCRPGGLVLADDSGLEVRALGLLPGVRSARFAEDAEYLPGSPLSADERNNLLLMDRMRGVEDRAGRYVCVLSVARDGVEIASAEGEVAGEILGVPQGTGGFGYDPLFYLPELEKTMAEIDLETKLRLSHRGAALRVLLARLPG
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: R1AB_CVCAI
Sequence: PNTKSIDGENTSKDGFFTYVNGFIKEKLSLGGSAAIKITEFSWNKDLYELIQRFEYWTVFCTSVNTSSSEGFLIGVNYLGPYCDRAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLKKGKLLIRNNGKLLNFGNHLVNVP
What is the function of this protein?
The replicase polyprotein of coronaviruses is a multifunctional protein: it contains the activities necessary for the transcription of negative stranded RNA, leader RNA, subgenomic mRNAs and progeny virion RNA as well as proteinases responsible for the cleavage of the polyprotein into functional products.
What are the official names of this protein?
Replicase polyprotein 1ab, pp1ab, ORF1ab polyprotein.
Protein: SECY1_LACKZ
Sequence: MFSTLKNAFKDKEIRNKIYFTLFILLLYRIGANITVPGINVKAITQVAQTGLVPMLDTVSGGGLDNYSIFSLGVSPYITAQIVIQLLQMDIVPTLVEWGKQGEVGRRKTNQVTRYLTLVVAFVQSIGITLGFNALTQMGLVKNQTPQTYVEIAIIMTAGTMLLTWLGDEITDKGLGNGVSVIIFAGIIARLPSGLYQIYKEEIINNSASDRWQGILFFIAVIVAILIVTQLVTWVEQADRRIPIQYTRRATISGSESFLPLKVNVSGVIPVIFASSFIVTPATILMAFQRTQGDQQWFKVMNQIFSLQTTPGVIIYTLLIILFTFFYAFVQVNPEKLAENLQKQGAYIPSVWPGKDTQDYVSKMLIKLSTVGSIFLGLVALLPQLATNFWNLPSSIGLGGTSLLIVIGVVLELSRQINGLLMKREYVGFIR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY 1.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL5_NEOSM
Sequence: MLESEYHKSALARVMKEVGVDSPVKAPRFEKVCLSVGLGGASSDSKLLASAVEDLSLIAGQKAVVTVAKKSISSFKLRKGFPVGCRVTLRKRRMFDFINRLLYMALPDQKDFKGFTMRNFDGHGNMAFGLTEHIVFPEVDFDKTYRIIGMNVVVVTTASTDQLARILLSCYGFPFRD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NU1M_TETNG
Sequence: MITTLITHILNPLAFIVPVLLAVAFLTLLERKVLGYMQLRKGPNIVGPYGLLQPIADGVKLFIKEPVRPSTSSPILFILTPMLALTLAMTLWAPLPLPYPVLDLNLAILLFVALSSLAVYSILGSGWASNSKYALVGALRAVAQTISYEVSLGLILLSLIIFTGGFTLQTFNTAQESIWLIIPAWPLAAMWYISTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFFLAEYANILFMNTLSASLFLGASHIPMLPELTTMNLMTKAAVLSLVFLWVRASYPRFRYDQLMHLIWKNFLPLTLALVIWHLALPITFAGLPPQM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL5_PARL1
Sequence: MAEAQYIPRLKVQYLEKFRPELTEKFSYKNLLEVPRLDKIVLNMGVGEAVGDSKKIKSAFEDLQAIAGQKPVITKAKTSIATFKLREGMPIGVKVTLRKDRMYEFLDRLVTVALPRVRDFRGLNAKSFDGRGNYAMGLKEHIVFPEIDYDKVDQIWGMDIIVCTTAKTDDEARELLRKFNFPFTK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MURB_MYCBO
Sequence: MKRSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTDLTVVRLANSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCML
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y693_AQUAE
Sequence: MLKRLMLASAILPVVSFAESDPLDVLLKKLEEKGVITKEEAKEVKKVAKKHPHLKVKIRLQPRIDFGDIYKENNDYKSRSDFYFRRVRLEISKEWKNIPFGKKLKINFTLHSDKGERDYDYKKGEKEHHSFDPKVKYAYADWTFVDEFAVRIGKNKIPYSRVSLTSSSRQLLIERPYVTEDAKKWLGDYDSNQIMFHGKVAGGIFRYMLSIWDGSTIESKNKTGGTVKADTSLGDAYAIRLEFSPPGFVEKKKDDTGIGEKNKGDVISVGLNYAKNSDFDITDKNIKNEEATVWGGDIFGRFHLGPGALVAQAEYVKMKYDKLDLEEKGYYIQAGYLIPTPYGKFEPAARYEHFKQEDKKNDVTKHKKDIITLGFNHYIKGHKIKWGYNVLFIDNKEKDEKDQTVHQIQMQFYF
What are the official names of this protein?
Uncharacterized protein aq_693.
Protein: SYI_SHIDS
Sequence: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAIDQDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDSQAVILAKDLVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAWWDLDAKELLGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGLADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALGDELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKVAEHAEICGRCVSNVAGDGEKRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_CHESB
Sequence: MAKTVYVLNGPNLNTLGKREPGIYGGKTLADIEADCRAAAAGLGLEVEFRQSNHEGMLIDWIHEAGERGAGIVLNPGAYGHTSIALHDAIRAVSPLPVIEVHLSNIHAREPFRHRTMTAPVVAGMICGLGPIGYTLALQALAARL
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: NHAA_BARHE
Sequence: MSDLSSNRLPNRASRVTNQALSAIERFLHIEALSGVVLLLAAAAALMFANSEYASLYESFWHTPLGFNFGHFTLSWDLHFWVNDALMAVFFLVAGMEIRREIHEGALADFKQAILPIVAAIGGVCLPAIIYFSFNFNSGQIHGWAVPTATDIAFALGILALLGKKIPSNLHIILLSLAIIDDIIAVLIIAFFYSTNIDPSGLVIAIAGIALVLFFQWIGFASAWLYILPGAIIWWGLMVTGIHPSLAGVILGMMTPVLPTRTLIAPLTILSNAMQILQEKNTKTDLHHISTALKKMRKGQRDIIAPVTRIQKALHPWVAYGVMPIFAFANAGVSFANFDLSSDKSFLIVLGVVIGLFIGKPLGIITASYLAVKSGLCRLPPQMTWAGILLIGFLAGIGFTMSIFVSMLAFKDIVLLDSAKIGVLCGSGLSALIGLGYGLIYIKRNKKASHSSQ
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPP_THEMA
Sequence: MTVKEKKIIDQYVPIVVESTGRYERAYDIFSRLLKDRIVFLGSPIDDYVANLVIAQLLFLEAEDPDKDVYLYINSPGGSVTAGLAIYDTMQYIKCDVSTICVGQAASMAAVLLAAGAKGKRYALPNARIMIHQPLGGAEGPAKDVEIITRELLRIKDLLNRILSKHTGQPIEKIEKDTDRDFFMSAEEAKEYGIVDKVVSTRE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIRB4_BRUA2
Sequence: MGAQSKYAQQLNNERSLAPFIPFRSQVGPTTVITRDGDFVRTWRIAGLAFETQDKEKLLIRKDQLNTLFRAIASNNVALWSHNVRRRTWDHLKSFFSNPFCDALDKKYYGSFSGYRMMSNELYLTVIYRPVPAKISRLFNVAVHRSHAEILQEQQLAIRKLDEIGNQIETSLRRYGGDDGRGIEVLSTYEDKHGALCSQQLEFYNFLLSGEWQKVRVPSCPLDEYLGTGWVYAGTETIEIRTANATRYARGIDFKDYANHTEPGILNGLMYSDYEYVITQSFSFMTKRDGKEFLTRQKQRLQNTEDGSASQIMEMDIAIDQLGRGDFVMGEYHYSLLVFAEDMETVRHNTSHAMNILQDNGFLATVIATATDAAFYAQLPCNWRYRPRVAGLTSLNFAGLSCFHNFRAGKRDGNPWGQALTLLKTPSGQPAYLNFHYSKGDEDNFDKKLLGNTRIIGQSGAGKTVLMNFCLAQAQKYLHNAPMGMCNVFFDKDQGAKGTILAIGGKYLAIRNGEPTGFNPFQMEPTAGNILFLEKLVQVLVSRDGQHVTTTDESRISHAIRTVMRMRPELRRLSTVLQNVTEGSDRQDRENSVAKRLAKWCFDDGTGKRGTFWWVLDCPQDQIDFNTHSNYGFDGTDFLDNADVRTPISMYLLHRMELAIDGRRFIYWMDEAWKWVDDEAFSEFANNKQLTIRKQNGLGVFATQMPSSLLNSKVASALVQQVATEIYLPNPKADYHEYTDGFKVTNEEFDIIRSMSEESRMFLVKQGHHSMICRLELNGFDDELAILSGSSDNNELLDQVIAEVGDDPSVWLPVFQERRKARIASSKSTGR
What is the function of this protein?
The virB operon is essential for intracellular survival and is not involved in the invasion process.  Constitutes a major determinant of virulence in mice.
What are the official names of this protein?
Type IV secretion system protein virB4.
What is the protein family that this protein belongs to?
Belongs to the TrbE/VirB4 family.
Protein: RL17_THEAB
Sequence: MRHRMKRHRIGRYGSHRKATLRNLSREIVEHGSIITTTPKAKAVQIFFEKLMTKAVKAKKADKKEREVALRREIFKALGDRRLVNKLVDEIAPKYLDRQGGYTAIYKVGPRRGDGAEMSLIKLVIEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: CCL11_CAVPO
Sequence: MKVSTAFLCLLLTVSAFSAQVLAHPGIPSACCFRVTNKKISFQRLKSYKIITSSKCPQTAIVFEIKPDKMICADPKKKWVQDAKKYLDQISQTTKP
What is the function of this protein?
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils (By similarity).  Binds to CCR3 (By similarity).
What are the official names of this protein?
Eotaxin, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YGFB_SALDC
Sequence: MSIQNEMPGYNEMNRFLNQQGAGLTPAEMHGLISGMICGGNNDSSWQPLLHDLTNEGLAFGHELAQALRKMHAATSDALEDDGFLFQLYLPEGDDVSVFDRADALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDESEDQEELEMSLEEIIEYVRVAALLCHDTFTRQQPTAPEVRKPTLH
What are the official names of this protein?
UPF0149 protein YgfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: TRMD_PSECP
Sequence: MRIDVVSIFPEYLAPLELSLIGKARQDGILDLHVHDLRSFTTDRHRTVDDTPYGGGAGMVMKPEPWSQALTAVAEARRGHQGKPVLIVPSPAGERFTQALAHELAGEEHLAFACGRYEGIDERVIEWAGEHFDVRPVSLGDYVLNGGEVAVLAMVEAVGRLLPGVVGNPESLVEESHSDGLLEYPVYTKPAVWRDREVPAILLSGNHGKIAQWRRHEQFRRTSERRPDLLEVFDAGKLPKADRLALQELGYDIVDGRPVRRQGTAEPAG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFNA2_CHICK
Sequence: MPRWEAAALLAAIVGVCVWSDDPGKVISDRYAVYWNRSNPRFHRGDYTVEVSINDYLDIYCPHYEEPLPAERMERYVLYMVNYEGHASCDHRQKGFKRWECNRPDSPSGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISASPLNVVDRPCLKLKVYVRPTNDSLYESPEPIFTSNNSCCSLAVPRAVLVAAPVFWTLLGS
What is the function of this protein?
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.  Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity).
What are the official names of this protein?
Ephrin-A2, ELF-1, EPH-related receptor tyrosine kinase ligand 6, LERK-6.
What is the protein family that this protein belongs to?
Belongs to the ephrin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: BRK1_TRICX
Sequence: GPNPGFSPFR
What is the function of this protein?
Causes constriction on isolated rat ileum preparations and relaxation on rat duodenum muscle preparations at amounts higher than bradykinin.  Is a partial agonist bradykinin receptor B2 (BDKRB2).  Is moderately lethal to honeybees.  May be related to the predation of insects by the spider webs.
What are the official names of this protein?
Nephilakinin-1, Nephilakinin-I.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL3_MICAN
Sequence: MSIGILGTKLGMTQIFDNKTGVAIPVTVVQAGPCPVTQVKTKKTDGYESIQVGYKTVKEKALNKPLLGHLAKAGVSPLRHLIEYRLEDASAYTLGQEITADIFQEGDLVDVAGTTIGRGFSGYQKRHNFKRGNMTHGSKNHRLPGSTGAGTTPGRVFPGKRMAGQYGSTQVTIRKLSVVKIDSERNLILIKGAVPGKPGTLLNITPAKKFGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL21_BACFN
Sequence: MYAIVEINGQQFKAEAGQKLFVHHIQNAENGATVEFDKVLLVDKDGNVTVGAPTVDGAKVVCQIVSSLVKGDKVLVFHKKRRKGHRKLNGHRQQFTELTITEVVA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: COMB_CLOP1
Sequence: MKIDVIISADYIDSEALKGKIAVVIDMLRATSVITTALYNGAKKVIPVVSVEEAFEKAKELKSLGEEVLLGGERKALKIDGFDFSNSPLEYKREIVEGKNVIMSTTNGTRALNLCSKADKVIVASVLNGQAVAKYLENEEKEIVFVNSGTNGEFSSDDFMCAGYIISELCKNKEAELTDIAKTAKYVYESSEGIEEFIKDAKHYNILKNLGLEEDLKYCSTKNLIDLVFEFKNGEIKTVESGVKVTI
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: PBPX_BACSU
Sequence: MTSPTRRRTAKRRRRKLNKRGKLLFGLLAVMVCITIWNALHRNSEENEPSQETAAVSNTDQKKEVKKKTAKKSEEQIKTVDRNQKISNYLKEIGFSGTAMIVRNGEIVTNKGFGYADRKHYIQNNPLTSFYVGSSQKALIATAILQLEEKGKLQTSDPVSTYLPHFPNGQTITLKNLLTHTSGINGHIEGNGAITPDDLIKDIELQGIKRQPGVWDYKDSNYSVLAYIIAEVSGEPYEQYIKNHIFKPAGMTHAGFYKTYEKEPYPAVGYKMEGSKTVTPYIPDLSQLYGAGDIYMSAIDMYKFDQALIDGKLYSQKSYEKMFTPGSSSTYGMGFYVAPGSYSNHGVMPGFNILNSFSKSGQTIVILFSNIQNNAKLGQVNNKIYQLLNQE
What are the official names of this protein?
Putative penicillin-binding protein PbpX.
What is the protein family that this protein belongs to?
Belongs to the beta-lactamase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Localizes to the division septum during vegetative growth, and accumulates at the prespore during sporulation.
Protein: PGK_NAUPA
Sequence: MKINSPKDLDFKPGSSVFLRCDFNVPLDEFGNITDDRRIRMALPTIKYLLDNECKIVIASHLGRPKGEFDEKYSLKPVAKRLSHLLKQDVIMAKDVVGPDAKEKASKLQNGEILLLENVRFDPRETKNDEGFAKELSEFGEFYINDAFGVSHRAHASVEAITRFYDNEHKAAGFLLLKEINFFYKLLENPVRPFVAVVGGSKVSGKLQALINLLPKVDKIIIGGGMAFTFLKAMGYNVGNSLVEDELIDEALKIMAEAKRLGVKFYLPVDIVIADKFAEDAMVKYVTAQEIPDGWMGLDIGPASVRLFGEVLWDAQTILWNGPMGVFEMDKFSRGTFKISHEIARSHGIKVVGGGDTADAVQRAGDDEEMTFISTGGGASLELLEGKKLPGIAALEIK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_STAAC
Sequence: MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: PPIL2_CAEEL
Sequence: MGKKQHQKDKLYLTTSEWKSIGGHKDDTGTRLQRAQFKRLPINHCSLSLLPFEDPVCARSGEIFDLTAIVPYLKKHGKNPCTGKPLVAKDLIHLKFDKGEDGKFRCPVTFRTFTDHSHILAIATSGNVYSHEAVQELNLKRNHLKDLLTDVPFTRADIIDLQDPNHLEKFNMEQFLHVKLDLKTSEEIKKEKDAMKDPKFYIRRMNNACKSVLDQLDKEYVPKKSSTETDETADEINAAHYSQGKVAAGFTSTVMAPVTSNKAAVLDNDTVRYSRVKKNAFVRLVTNFGPLNLELFAPKVPKACENFITHCSNGYYNNTKFHRLIKNFMLQGGDPTGTGHGGESIWDKPFSDEFISGFSHDARGVLSMANKGSNTNGSQFFITFRPCKYLDRKHTIFGRLVGGQDTLTTIEKLETEEGTDVPMVSVVIMRAEVFVDPFEEAEKEVQAERAEILKKTSKDAASLANKKAKETATKPEAVGTGVGKYMKSAAAVNKRQGKMEDVPLEAAKKTKFARAGLGDFSKW
What is the function of this protein?
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins.  May also function as a chaperone, playing a role in intracellular transport of proteins.  May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.  Influences the hermaphrodite switch from spermatogenesis to oogenesis.  Required for body wall muscle cell development.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase 4, PPIase 4, Cyclophilin mog-6, Cyclophilin-4, Masculinization of germline protein 6, RING-type E3 ubiquitin transferase isomerase 4, Rotamase 4.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
What are the subcellular locations of this protein?
Nucleus.