PharMolix/UniProtQA huggingface dataset:
Protein: Y6280_PSEA7
Sequence: MLSWAITFLIIAIIAAVLGFGGIAGAATGIAKILFVLFLVLFVVSFFFGRRRG
What are the official names of this protein?
UPF0391 membrane protein PSPA7_6280.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: T2E1_HERAU
Sequence: MAINPITRNKIKDYLNSFIQQQLSVYRERSLREFQDVDSYLPSLSKDGDLKPFHASLIPASIMRLNRFERSLSTGLGSTFEECTRLIALDHHAVALRNYDIQAALDQAQWAAIDQLISIIDRGLKHQTPSLNQMLEQIQSIPLTGILETHIVRADLYIQRHDGSELFFEIKSPKPNKGQCLEVMQRLLRIYTIKQQSAVPVKAFYAMAYNPWGISRASYRSSNTKKYTDFSNAVVIGQEFWSLIGEPSTYTELLEIYHEVGLAKSAEITQKLLQ
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GGWCC-3' and cleaves after G-1 (PubMed:7607523, PubMed:12654995).  This system is more active than isoschizomeric RM. HgiBI (PubMed:7607523).
What are the official names of this protein?
Type II restriction enzyme HgiEI, R.HgiEI, Endonuclease HgiEI, Type-2 restriction enzyme HgiEI.
What is the protein family that this protein belongs to?
Belongs to the TdeIII type II restriction endonuclease family.
Protein: GLR32_ARATH
Sequence: MFWVLVLLSFIVLIGDGMISEGAGLRPRYVDVGAIFSLGTLQGEVTNIAMKAAEEDVNSDPSFLGGSKLRITTYDAKRNGFLTIMGALQFMETDAVAIIGPQTSIMAHVLSHLANELSVPMLSFTALDPSLSALQFPFFVQTAPSDLFLMRAIAEMISYYGWSEVIALYNDDDNSRNGITALGDELEGRRCKISYKAVLPLDVVITSPREIINELVKIQGMESRVIIVNTFPKTGKKIFEEAQKLGMMEKGYVWIATTWLTSLLDSVNPLPAKTAESLRGVLTLRIHTPNSKKKKDFVARWNKLSNGTVGLNVYGLYAYDTVWIIARAVKRLLDSRANISFSSDPKLTSMKGGGSLNLGALSIFDQGSQFLDYIVNTNMTGVTGQIQFLPDRSMIQPSYDIINVVDDGFRQIGYWSNHSGLSIIPPESLYKKLSNRSSSNQHLNNVTWPGGTSETPRGWVFPNNGRRLRIGVPDRASFKEFVSRLDGSNKVQGYAIDVFEAAVKLISYPVPHEFVLFGDGLKNPNFNEFVNNVTIGVFDAVVGDIAIVTKRTRIVDFTQPYIESGLVVVAPVTKLNDTPWAFLRPFTPPMWAVTAAFFLIVGSVIWILEHRINDEFRGPPRKQIVTILWFSFSTMFFSHRENTVSTLGRAVLLIWLFVVLIITSSYTASLTSILTVQQLNSPIRGVDTLISSSGRVGFQVGSYAENYMIDELNIARSRLVPLGSPKEYAAALQNGTVAAIVDERPYVDLFLSEFCGFAIRGQEFTRSGWGFAFPRDSPLAIDMSTAILGLSETGQLQKIHDKWLSRSNCSNLNGSVSDEDSEQLKLRSFWGLFLVCGISCFIALFIYFFKIVRDFFRHGKYDEEATVPSPESSRSKSLQTFLAYFDEKEDESKRRMKRKRNDDLSLKPSRPI
What is the function of this protein?
Glutamate-gated receptor that probably acts as non-selective cation channel (Probable).  May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells (Probable).  Could play a role in calcium unloading from the xylem vessels (PubMed:11158446).  Acts as negative regulator of lateral root initiation and development (PubMed:23590882).  May restrict primordia numbers and position along the root axis by a signaling process originating in the phloem (PubMed:23590882).
What are the official names of this protein?
Glutamate receptor 3.2, AtGLR3.2, AtGluR2, Glutamate receptor-like protein 3.2, Ligand-gated ion channel 3.2.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the plasma membrane.
Protein: RL351_ENCCU
Sequence: MKIEASALRQLGIKQIEERAAEIKADLAALRQKKNSGDVGANDIKTAKKNLARALTVRREKILEELVEAYRGTPVSKLPKELRPKLNRSKRRALTKTQLRRKTRRQRARMSKFPRVIFAYNE
What are the official names of this protein?
60S ribosomal protein L35-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CI114_MOUSE
Sequence: MAERPRKRPCGPGEHGQRVEWRKWKQQKKEEKKKWKDLKIMKKLERQRAQEEEAKRQEEEEEAAAQRSNQGRPYTLSVALPGSILDNAQSPELRTYLAGQIARACTIFCVDEIVVFDEEGQDTKSVEGEFRGVGKKGQACVQLARILQYLECPQYLRKAFFPKHQDLQFAGILNPLDSPHHMRQDEESEFREGVVVDRPTKAGHGSLVNCGMKKEVKIDKKLDPGLRVTVRLNQQQLPECKTYKGTVVSSQDPRTKAGLYWGYTVRLASCLSAVFAEAPFQDGYDLTIGTSERGSDVASAQLPSFRHALVVFGGLQGLEAAVDADPNLEVADPSVLFDFYVNTCLSQGSRTIRTEEAILISLAALQPGLTQVGSRPASPLSGPRM
What is the function of this protein?
Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase.  Also involved in chromosome alignment.  May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis.  Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level (By similarity).
What are the official names of this protein?
Putative methyltransferase C9orf114 homolog, Centromere protein 32, CENP-32, Kinetochore-associated protein, SPOUT domain-containing methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associated with the outer kinetochore.
Protein: EFG_BIFLO
Sequence: MAEEISDLHDVRNIGIMAHIDAGKTTTTERILFYTGKNYKIGETHDGASTMDFMAQEQERGITIQSAATTCFWSRQSHDTKDKFQINIIDTPGHVDFTAEVERSLRVLDGAVAVFDGKEGVEPQSETVWRQADKYGVPRICFINKMDKLGANFYYSVDTIKEKLGATPIVMQLPIGSENDFTGVVDLVEMQAYVWNGTEELGAKYDTTEIPDDLKDKAQEYHEKLVEAAAEADDDLMNKFFEDGDLSKEDIRAGVRKLTIAKEAFPIFCGSAFKDKGVQPMLDGVVDYLPSPEDVPAIKGYKPGDESVEIDRHPVKSDPFAALVFKISTHPFYGKLVFVRVYSGSVVPGDSVLDSTREKKERIGKIFQMHADKENPMDRADAGNIYTFVGLKNVTTGDTLCAIDDPITLDSMTFPDPVIQVAVEPKTKADQEKMGIALSKLAEEDPTFQVTTDEESGQTLIAGMGELQLDIIVDRMRREFKVECNQGKPQVAYRETIRKAVMDQGYTHKKQTGGSGQFAKVLMNFEPLDTTEGKTFEFENKVTGGHISAEFIGPIEAGVKEAMESGVLAGFPVVGVKATVTDGQMHPVDSSEMAFKLAGSMCFKEAAPKAKPVILEPIMKVEVRTPEEYMGEVIGDLNQRRGNIQSMTDGVGVKVIDAKVPLSEMFGYIGDLRSKTQGRAMFTMEMDSYDEVPKSVSEEIIKAQRGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_CHLL2
Sequence: MRKVKPARKLGRTAAHRKATLANLTTQLLVYKRIETTEAKAKETRKVVEKIITKARKGTVHAQREIFKSIRDKEAVKMLFEDIVSKIGDRNGGYTRIIKLAPRFGDAAKMAVIELVDYAEAPSKQLPGKQDRAKRVKGSKKTEVVAAAAGE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: TCAA_STAHJ
Sequence: MSICPKCGQKIDSNLNKCPNCGNKLDNKDNQINSPQINTSNIRIRKFIPWAIVAFIIVLLIIVFVLVRNYNSPDAQTKILVNAIDNNDSQKVATLLSSKNSHIDSDEASVYIDYIRSEVGMKKFARDIKSTVETLNKSDSKEAINLKTRAGNNYLRVSKNGTRLLIFDNMSYTAPTKKAIVKPKLDTKYEFKDGGKKKTVIADANKTTSLGTYIPGIYSVDAKKETEYGEFSGQLKFDFRYGKSNTVEVNENFNEALLTVKLKGKSDLDKDSLKVEINDKQMKYSSSREYGPYPQTKDVTVSALGKAKGKTFHAETKTIKARDLGNINSATLEFDDEEISDYIEEKEAEENSLKTKLSNFFSNYSFTLNSAISRSDFNLVSTFLKDKSSIYKSIKNNLNQSVAFINPQVISASQKGNTINTKVQHLNSNGQYETTNYELREDSDTGNIQLVDSK
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACPS_RALSO
Sequence: MSGAIYGIGTDIIQIERVEGVMQRTHGRFAEKVLGPDELRIYQARKARSERRGLAFLATRFAAKEAVSKAIGLGMHWPMTWRAVQTLNLPSGQPVVRYSGELADWIAQRGLHIQISVTDERDYAVAFAVAELQSKLSA
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_BDEBA
Sequence: MKWIGLTGGIACGKSTVSRMLRTHDIPVVDADEIAKEVVKPGSAGLKSVIQEFGPEFLTADGALDRRKLGQKVFGHPELLHKLEAITHPLIREETRRRRRLYEDMGHKLAIYDIPLLFETRAKDQFDGVIVVACTKEQQKERLRRQNWSEDEIEMRIASQIPIQFKEQQADFVLHNNRDEQHLLREVDRVLKWLEELKNQN
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA1_YEAS7
Sequence: MSLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTFGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRSDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRDPEEVEQQVAEEATTEEAGEEEAKEEVTEEQAEATEWAEENADNVEW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0-A, Nucleic acid-binding protein NAB1A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ARGC_LACP7
Sequence: MIKVGIIGSTGYAGQELVRILLQHKEVSIVWYGSKSYIDKKYSEVFQNMFQIVEESCFDDNMEELARHVDVIFTATPQGFCASVMTEDILSKVKVIDLSADYRIKDVKTYEEWYGIKHNSPDFLKEAVYGLCEFNREDIKKARLIANPGCYPTCSILSIYPLIKEGIIETDSIIIDAKSGVSGAGRGAKVDNLYCEVNENMKAYGVSTHRHTPEIEEQFSLITLENVTINFTPHLVPMNRGILITAYGKLKKRVSYEEVKEIYDRYYEKEYFVRVLEKGMPPETRWVEGSNFVDVNFVIDNRTNRIIMMGAMDNLVKGAAGQAVQNMNLMFGLPEQEGLKLVPMFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_ACIET
Sequence: MTSPSAPLTGSIVALVTPMHDDGSVDYPALRKLIDWHIAEGTDCIGVVGTTGESPTVNVEEHCEIIRVSVEQAAKRVPIMAGCGANSTAEAIELARFAKKVGADSQLQVVPYYNKPTQEGQYRHFKAIAEAVGDLPMVLYNVPGRSVADMQHETVLRLTQVPGIVGIKEATGNIERAQWLIRDVPKGFAVYSGDDPTAVALMLCGGQGNISVTANVAPRLMHELCVAALAGDTRRAMEIQFRLMPVHKQLFVEANPIPVKWAVQRMGLCGGALRLPMTPLSQGNEAVVEAALRAAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_AZOC5
Sequence: MQRLVARAPAKVNLTLRILRRRPDGFHDLASIVAFAGACDVVTLESDAPLGLAVAGPSAAAAGPDADNLILRAADAFARHVPGARLGRFTLTKRLPVAAGIGGGSSDAAAALRLLAQINDIALDDPRLHAAAREVGADVPVCLDPQARIMEGIGERLSEPLGLAPLFAVLVNCRVPVPTADVFRTLGLRAGEDLAGLPHEAPMSTGRAAVMRHLVLHGNDLEPPAETVAPEITRVKAMLAQEPEVRLVRMSGSGATVFALTDDCRAAAQVARRVAAAEPGWWVRPTVLR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: VF349_IIV3
Sequence: MDQTNLRRCLATYFGDEKNINHILKKTAGPDQMVQIYQILTTIENPSHSEQDNFRRAVTMVKQNQLGWGHPIFQPEQQKISEENDFITCPYEVSEGVLRCGKCDCTKILWFSKQTRSMDEPTTIFASCSNCKTRWTE
What are the official names of this protein?
Putative transcription elongation factor S-II-like protein 055R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 349L family.
Protein: IF2_COXBU
Sequence: MADMSVKQLADLVRTTPERLLEQLKEAGVAITHVDQTISDEEKRKLLLHLKTSHSTETDKKRSKIVLKRKKLSVVKSGKKSVNVEIRSKRTYTKPVVEQKRETEPAPTQEVPPTSDTTNLNEKAEVNVATLEKAVEAEVKEEAKKTPSEKKETPKKGPRKETRRSRKPDKEDKWEREELHMTKLVEERRRRHKPAHMPDSDSASAKLEQGFARPTAPVVREVALPESITVADLAQKMSVKAAEVIKAMMKLGAMVTINQRIDQETAAIVVEEMGHKPKLIKEDVLEENLVATLGEQTGEAVPRAPVVTIMGHVDHGKTSLLDYIRRTKVTSTEAGGITQHIGAYHVETELGMITFLDTPGHEAFTAMRARGAKCTDIVVLVVAADDGVMPQTVEAIQHARAAKVPVVVAVNKIDKPEADPERIKTELSTHDVLPEEWGGDTMFQPISAKTGEGIDALLERILLQAEVLELKAVDNGPARGMVVESRLDRGRGPVATVLVTSGELHLGDILLVGREYGRVRAMIGDDGRPCESAGPSMPVEVLGLSGTSVAGEEAIVVPDERKAREIARFRQGKYREVRLAKKQTAHLERIFDRMGEGKQNTLNIVLKADVQGSLEALTEALNKLSTDEVKVNIIASGVGGITESDVNLAIASDAVVIGFNVRADAPTRVLVEREGVDLRYYSIIYDLIDEVKKALSGLLAPEFEEKIVGLAEVRDVFRSSKIGAIAGCMVVEGVVRRHLPIRVLRDNVVIYEGQLESLRRYKEDVAEVRQGTECGIGVKNYNDVKVGDQIEVYEKTQVHRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAL4_ECOLX
Sequence: MAKIHMVLQGKGGVGKSAIAAIIAQYKMDKGQTPLCIDTDPVNATFEGYKALNVRRLNIMAGDEINSRNFDTLVELIAPTKDDVVIDNGASSFVPLSHYLISNQVPALLQEMGHELVIHTVVTGGQALLDTVSGFAQLASQFPAEALFVVWLNPYWGPIEHEGKSFEQMKAYTANKARVSSIIQIPALKEETYGRDFSDMLQERLTFDQALADESLTIMTRQRLKIVRRGLFEQLDAAAVL
What are the official names of this protein?
Protein TraL.
What is the protein family that this protein belongs to?
To plasmid R751 TraL.
Protein: NU1C_SYNJA
Sequence: MTTAGIDLQLGFETALQNLGLSPGAAHALWVPLPMLLMVIAATLGVMVMTWLERKISAAAQQRIGPNMAGPQGVLIPIADGIKLLTKEDVLPSLADPVLFTLGPILVFLPVFLCYLVVPFGQNLLISNIAIGVFFLIATSSVQPIGLLMSGYGSNNKYSLLGGLRAAAQSISYELPLALSVLAVVLMSNGLDTVGIVEQQSGLGILSWNVWRQPIGFVIFLISALAETERIPFDLPEAEEELVAGYQTEYSGMKFALFYLGSYANLLLASLIAAVLYLGGWSFVVPVETIAAWLGIPLDNPFLQIGAAVLGILMTMVKAFIFVFLAILLRWTLPRVRIDQLLDLGWKFLLPVSFVNLLLTAALKLAFPTFFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: FAD3_MYCTU
Sequence: MINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRELG
What is the function of this protein?
Involved in the catabolism of the rings C and D of cholesterol.  Catalyzes the ATP-dependent CoA thioesterification of 3aalpha-H-4alpha(3'-propanoate)-7abeta-methylhexahydro-1,5-indanedione (HIP) to yield HIP-CoA.  It can also use the hydroxylated analogs of HIP, 5alpha-OH HIP and 1beta-OH HIP.  It requires that the side chain at C17 is completely removed.
What are the official names of this protein?
3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase, HIP:CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: YHFA_BACSU
Sequence: MMEVGILPVHVLYVFFIGAIILFMLLRKDTTFISLFGIFIISLWASHSLSASVSSLFHSFIYAAGELLPTIFIICFIVSMSDLLTKTGINEAMISPFASLVRGPVTAYWLIGGLMFAISLFFWPSPGVALIGAVLLPAAARAGLTPLAAAMAMNLFGHGFALSGDFVIQAAPKLTADAAGIPVGDVVSASIPLVLIMGVTTTTAAFIMIQRERKKQEHPTSFSPVLSGEQDNSLYLPKRLRSILAFLIPLAFLADIACMLLFNLQGNDATALIGGSAICILFTVHFFVYKHKGLEKITGYFIDGFKFGFKVFGPVIPIAAFFYLGDSGYESILGTSLPKGSHGIVNDLGIALSHMMPMSKELAATALTAAGAITGLDGSGFSGISLAGSIAKLFSSALHADPAILTALGQISAIWVGGGTLVPWALIPAAAICKVDPFELARKNFIPVAIGLLVTTLAAVMML
What are the official names of this protein?
Uncharacterized membrane protein YhfA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TF7L2_HUMAN
Sequence: MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE
What is the function of this protein?
Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner.  Acts as repressor in the absence of CTNNB1, and as activator in its presence.  Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1.  TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1.  Expression of dominant-negative mutants results in cell-cycle arrest in G1.  Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
What are the official names of this protein?
Transcription factor 7-like 2, HMG box transcription factor 4, T-cell-specific transcription factor 4, T-cell factor 4, TCF-4, hTCF-4.
What is the protein family that this protein belongs to?
Belongs to the TCF/LEF family.
What are the subcellular locations of this protein?
Nucleus, PML body. Note=Diffuse pattern. Colocalizes with SUMO1 and PIAS4 in a subset of PML (promyelocytic leukemia) nuclear bodies.
Protein: HYP2_AGABI
Sequence: MFSRVLVAALVALPVLVSASPTPGGYPDSTTVVSQCNVGELHCCNTQQTPDHTNAAGGLLGAAANVGALLGFDCTPISVIGIGGNNCAAQPVCCEANEFTGLINALSCSPINVNL
What are the official names of this protein?
Hydrophobin-2, Hydrophobin-C.
What is the protein family that this protein belongs to?
Belongs to the fungal hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: OBG_MARN8
Sequence: MKFVDEATIIVEAGKGGHGCLSFRREKYVPKGGPDGGDGGDGGSVYLEADSALNTLIDYRFQRKYKAQNGEPGAGRNCTGTKGEDLVLPVPVGTTVVDMDTHEVLGDLTKEGQRLKVAQGGFHGLGNTRFKSSVNRAPRQTSKGSEGEARNLRLELKVLADVGLLGLPNAGKSTFIRSVSAARPKVADYPFTTLVPNLGVVSVQAHQSFVIADIPGLIEGAAEGAGLGIRFLKHLVRTRLLLHLVDVAPYDGSSPADAVRAIAHELEKFSETLASRPRWLVLNKVDMVAEEDREAHCQAIVDELGWEGPVFRISALSGEGTKPLVQAVMRWIEEQAEQEADNPDFAEQEAARRRRMDEEARQKIEADRQARRAARNADDDDDFDDDDYDVEVVYAPE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIF22_HUMAN
Sequence: MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS
What is the function of this protein?
Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis.  Binds to microtubules and to DNA (By similarity).  Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells (PubMed:25743205).
What are the official names of this protein?
Kinesin-like protein KIF22, Kinesin-like DNA-binding protein, Kinesin-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton.
Protein: MEIG1_HUMAN
Sequence: MASSDVKPKSVSHAKKWSEEIENLYRFQQAGYRDETEYRQVKQVSMVDRWPETGYVKKLQRRDNTFYYYNKQRECDDKEVHKVKIYAY
What is the function of this protein?
Essential for spermiogenesis.
What are the official names of this protein?
Meiosis expressed gene 1 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the MEIG1 family.
Protein: FUCI_ECO55
Sequence: MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEAELEMALTWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_CYTH3
Sequence: MSKQELEIKTYVSDLLQERAELFLVDIAFSGTHSRRKILVILDKDSGILIDECGEFSRALGNLIEENNLFGDNAYVLEVSSPGMDRPLLVSRQYKRRIGNTLSFLLNDGTQFDAVLESVSEEGVVVMPAPQKVKKSNKKEAVVDVAIEPRKLRFEEIKKCNLIVSFK
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.