PharMolix/UniProtQA huggingface dataset:
Protein: MANA_HYPJR
Sequence: MMMLSKSLLSAATAASALAAVLQPVPRASSFVTISGTQFNIDGKVGYFAGTNCYWCSFLTNHADVDSTFSHISSSGLKVVRVWGFNDVNTQPSPGQIWFQKLSATGSTINTGADGLQTLDYVVQSAEQHNLKLIIPFVNNWSDYGGINAYVNAFGGNATTWYTNTAAQTQYRKYVQAVVSRYANSTAIFAWELGNEPRCNGCSTDVIVQWATSVSQYVKSLDSNHLVTLGDEGLGLSTGDGAYPYTYGEGTDFAKNVQIKSLDFGTFHLYPDSWGTNYTWGNGWIQTHAAACLAAGKPCVFEEYGAQQNPCTNEAPWQTTSLTTRGMGGDMFWQWGDTFANGAQSNSDPYTVWYNSSNWQCLVKNHVDAINGGTTTPPPVSSTTTTSSRTSSTPPPPGGSCSPLYGQCGGSGYTGPTCCAQGTCIYSNYWYSQCLNT
What is the function of this protein?
Endo-1,4-mannanase that catalyzes the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans and heteromannans.  It is a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.  Active against locust bean gum and ivory nut mannan, releasing mainly tri- and disaccharides (PubMed:7793911, Ref. 3, Ref. 4, PubMed:8529653).  Also has transglycosylation activity.  Transglycosylation of two mannotrioses into a mannohexaose is the major transglycosylation route (PubMed:8529653, Ref. 7, PubMed:24950755).
What are the official names of this protein?
Mannan endo-1,4-beta-mannosidase A, Beta-mannanase 5A, Man5A, Beta-mannanase I/II, BMANI, BMANII, Endo-beta-1,4-mannanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRR_LISMC
Sequence: MQKQVVVMDEAAIKRALTRVSYEIIERNKGTKNLALVGIKTRGIYLAERLHKRILEIEGIDVPVGDIDITLYRDDLSFKDDKTREPAVHGTNIPFDINGKKVVLVDDVLYTGRTVRAAMDALMDVGRPAQIHLAVLADRGHRELPIRADYVGKNIPTSGNERVEVRLTDVDNEEDAVIINKNE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: UVRC_SALDC
Sequence: MSEIFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQHIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPVRQCENSVYRNRSRPCLQYQIGRCLGPCVAGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLIARMEKASQDLAFEEAARIRDQIQAVRRVTERQFVSNAGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRRIHVQTKPRGDRARYLKLARTNAATALITKLSQQSTITQRLTALAAVLKLPAIKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNIAGITPGDDYAAMNQVLRRRYGKAIEESKIPDVILIDGGKGQLAQAKAVFAELDVPWDKHRPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSTLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SALTY
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNDDMIAQLESRIRAKASQLDEARRIDVLQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: KLAC_ECOLX
Sequence: MNATNTDVFAQVGGLEARGAKMKKRGTRFLIAALAVLAIAGIGAVTGWAISPSATPGSIDVPQVLASTFSDQVPGSEGGGLGGGLPFTSAVGAFTDFMAGPAIFTLGILGIVVAGAVLVFGGEFSGFVRSVCMMVIAVSMIFVSSNLVKGILGGDHDAGPAEPSPRARFMAAVEAKDFARVQELIEARGAKSAADYVLAQLAVAEGLDRKPGARVVVGKAAGSMAMPPAALGFTPRGEAAYAIERSAYGEPRSSIAKQYQQEWNRKAATWWAMAGVAGIIGAILAAAATGFVGLAVSIRNRVKRVRDLLVMEPGAEP
What is the function of this protein?
Belongs to the kla operon, which is associated with cryptic tellurite resistance, and IncW plasmid fertility inhibition.
What are the official names of this protein?
Protein KlaC, Protein TelB.
Protein: NADA_HALH5
Sequence: MNVFDTLQQSKKLPDVYRQMTRVELEERIRQHKERLGKKLLMLGHHYQRDEVFQFADQTGDSLQLAQIAAKEKEAQFIVFCGVHFMAETADLLTSEEQTVLLPDLRAGCSMADMADIHQTERAWERLQLMFGDTILPLTYVNSTAAIKAFCGRNGGATVTSSNAKKMLEWAFTQKERLLFLPDQHLGRNTAYELGIPLEAMAVWNPETERLETDQPLENIRVILWKGHCSVHEKFTVKHIEHLRKNEPDMSIIVHPECTHDVVIHADDAGSTHYIIKTIESADSGTKWAVGTEMNLVNRLANEHPDKEIVSLNPTMCPCLTMNRIDIEHLCWSLDQLAEGVFQHPIKVEDKDRGPALLALQRMLDRA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
Protein: MTAP2_MOUSE
Sequence: MADERKDEGKAPHWTSASLTEAAAHPHSPEMKDQGGAGEGLSRNANGFPYREEEEGAFGEHRSQGTYSDTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETANLPPSPPPSPASEQTATVEEDLLTASKMEFPEQEKFPSSFAEPLDKGEMEFKMPSKPGEDFEHAALVPDTSKTPQDKKDLQGMEGEKLPPVPFAQTFGTNLEDRKQSTEPSIVMPSIGLSAEPPAPKEPKDWFIEMPTESKKDEWGLAAPISPGPLTPMREKDVLEDIPRWEGKQFDSPMPSPFHGGSFTLPLDTMKNERVSEGPRPFAPVFFQSDDKVSLQDPSALATSKESSKDEEPLKDKADKVADVSISEVTTLLGNVHSPVVEGYVGENISGEVKVTTDQEKKETSAPSVQEPTLTETEPQTKLDEKSTVSIEEAVAKKEESFKLRDDKTGVIQTSTEQSFSKEDQKGQEHTIDELKQDSFPISLEQAVTDAAMTSKTLGKVTSEPEAVSERREIQGLFEEKTADKNKLEGAGSATIAEVEMPFYEDKSGMSKYFETSALKEDMTRSTELGSDYYELSDSRGSAQESLDTISPKNQHDEKELQAKASQPSPPAQEAGYSTLAQSYTPDHPSELPEEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCLDSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDDYLPPTTPAVEKMPCFPIESKEEEDKAEQAKVTGGQTIQVETSSESPFPAKEYYKNGTVMAPDLPEMLDLAGTRSRLASVSADAEVARRKSVPSEAMLAESSTSLPPVADESPVTVKPDSQLEDMGYCVFNKYTVPLPSPVQDSENLSGESGSFYEGTDDKVRRDLATDLSLIEVKLAAAGRVKDEFTAEKEASPPTSADKSRLSREFDHDRKANDKLDTVLEKSEEHIDSKEHAKESEEMGGKVELFGLGITYDQASTKELITTKDTSPEKTEKGLSSVPEVAEVEPTTKADQGLDFAATKAEPSQLDIKVSDFGQMASGMNVDAGKAIELKFEVAQELTLSSEAPQEADSFMGVESGHIKEGGKVNETEVKEKVTKPDLVHQEAVDKEESYESSGEHESLTMESLKPDEGKKETSPETSLIQDEVALKLSVEIPCPPPVSEADLSTDEKGEVQMEFIQLPKEESTETPDIPAIPSDVTQPQPEAIVSEPAEVPSEEEEIEAGGEYDKLLFRSDTLQISDLLVSESREEFVETCPGELKGVVESVVTIEDDFITVVQTTTDEGESGSHSVRFAAPAQPEEERRPRPHDEELEIEMAAEAQAEPKDGSPDAPATPEKEEVAFSEYKTETYDDYKDETTIDDSIMDADSLWVDTQDDDRSILTEQLETIPKEERAEKDARRPSLEKHRKEKPFKTGRGRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAELAKKSEVQAHSPSRKLILKPAIKYTRPTHLSCVKRKTTAASGDLAQAPGAFKQAKDKVTDGISKSPEKRSSLPRPSSILPPRRGVSGDREENSFSLNSSISSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPGTPKSGILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPSRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL
What is the function of this protein?
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization.  They also seem to have a stiffening effect on microtubules.
What are the official names of this protein?
Microtubule-associated protein 2, MAP-2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, dendrite.
Protein: SYH_JANSC
Sequence: MAKQKKQPRPKAETPKGFRDYFGAEVVERQTMLRKIGEVYHRYGFDPLETSAVETVEALGKFLPDVDRPNEGVFAFQEDGGSDDGKWLALRYDMTAPLARVAAQFRERPLPGQEDSLPSPYRRYTMGPVWRNEKPGPGRFRQFYQCDADTVGAPSVAADAEICAMLADCLEAVGIERGDYVVRVNNRKVLNGVMEVAGLAGDDKEAARGIVLRAIDKMDRLGAGGVRDLLGDGRKDESGDFTKGAGISSANADKILAFVQATAGDNAATVSNLKSLTEGSDIGTQGVSELEQIASLLAAQGYGPDRIIIDPSVVRGLGYYTGPVYEAELTFDVQNEKGQTVQFGSVAGGGRYDDLVKRFTGQEVPATGVSIGVDRLLAALHATGKLKGEDAGPVIVTVMDRDRMAEYQAMVATLRNAGIRAEVYLGNPKNFGNQLKYADKRRSPVAIIQGSDEAARGVVQLKDLILGAKLAEDATLEEWKSQPAQTEVAVADLVAEVQAIIARHK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_CALBD
Sequence: MITRNDVEYVANLARLTLTEEEIEKMTKELGAIIEFANKLSELNTEGIEPTAHVLNIYNVFRSDEVKPSYPREEILKNAPSHDDVCIKVPKIVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RUVC_SYNSC
Sequence: MRILGIDPGLARVGYGVIDIQDGCQRMLDCGIIQTNSDRSDGDRMVEIAGDLRQLIRIWRPELAAVEKFFFYRSSNTINVVQARGVVVMTLARFKIPMVEFPPMQIKLAVAGFGHAEKDEVLEAVMRELSLEEPPRPDDAADALAVALTAWLQR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PTER_MOUSE
Sequence: MSSLSGKVQTVLGLVEPSQLGRTLTHEHLTMTFDSFYCPPPPCHEVTSKEPIMMKNLFWIQKNPYSHRENLQLNQEVGAIREELLYFKAKGGGALVENTTTGLSRDVHTLKWLAEQTGVHIIAGAGFYVDATHSAATRAMSVEQLTDVLINEILHGADGTSIKCGVIGEIGCSWPLTDSERKILEATAHAQAQLGCPVIIHPGRNPGAPFQIIRILQEAGADISKTVMSHLDRTIFDKKELLEFAQLGCYLEYDLFGTELLNYQLSPDIDMPDDNKRIRRVHFLVDEGYEDRILMAHDIHTKHRLMKYGGHGYSHILTNIVPKMLLRGLTERVLDKILIENPKQWLTFK
What are the official names of this protein?
Phosphotriesterase-related protein, Parathion hydrolase-related protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
Protein: ARGB_BACFN
Sequence: MKEKMKEKLTVIKVGGKIVEEEATLNQLLNDFAAIEGHKVLVHGGGRSATKIAAQLGIDSKMVNGRRITDAETLKVVTMVYGGLVNKNIVAGLQARGVNALGLTGADMNVIRSMKRPVKEVDYGFVGDVERVDSTLLSDLIHKGVVPVMAPLTHDGQGNMLNTNADTIAGETAKALSAIFDVTLVYCFEKKGVLRDENDDESVIPQINHAEFQRYIAEGVIQGGMIPKLENSFEAINAGVSEVVITLASAIHTDGGTRIKK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A1I_MOUSE
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-I.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ATPD_RHIME
Sequence: MPVADTSQLISGVAERYASSLFELALDAGSIEAVGADLTRIQALIDGSDDLKRLIVSPVFSADDQFKAISALVEKFGFSGLVGNFLKVVARNRRLFVLPGIIKAFRLLAARHKGEITADVTSAHALTLAQEIELKAALKGVTGKDVAVNVTVDPSILGGLIVKVGSRQIDTSLRTKLSTLKLALKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MURG_ACICJ
Sequence: MRGAMLNPIVIAAGGTGGHMVPAESVADELMRRGQRIVLMTDARSAGQKSAVFAGCERHVLAGAGLAGRSLGRRLLGVAQLARGTVAARHILAKLDAAAVVGFGGYPSVPPVLAAATLRRRPAIVLHDQNAVLGGANRFLARFADHLALSFEGTVGLPGRARATVTGNPVRAAISVLAASPYEPPAETIRLLVLGGSLGARIFATLVPEALARLPEGLRRRIALTMQCPGEAIGAARGALDAAGITHELAPFFSDVAPRMAAAHLLVARSGGSTVAEVATIGRPAIFIPLAINTDQRHNADVLARRGGAFRLDQATTTPDRLAGVLESLLDDPLRLAAMAEAAASARIEEAAARLADLVLSAIAERVR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: URM1_YEAS7
Sequence: MVNVKVEFLGGLDAIFGKQRVHKIKMDKEDPVTVGDLIDHIVSTMINNPNDVSIFIEDDSIRPGIITLINDTDWELEGEKDYILEDGDIISFTSTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YQGF_STRA1
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEESGNFGFDRLAELVKEYKVDKFVVGLPKNMNNTSGPRVEASQAYGDKITELFNLPVEYQDERLTTVQAERMLVEQADISRGKRKKVIDKLAAQLILQNYLDRMF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y020_PYRFU
Sequence: MKIVWCGHACFLVEDRGTKILIDPYPDVDEDRIGKVDYILVTHEHMDHYGKTPLIAKLSDAEVIGPKTVYLMAISDGLTKVREIEVGQEIELGDIRVRAFFTEHPTSQYPLGYLIEGSKRVAHLGDTYYSPAFTELRGKVDVLLVPIGGKSTASVREAADIVEMIRPRIAVPMHYGTYSEADPEEFKKELQKRRIWVLVKDLKPYEGFEI
What are the official names of this protein?
UPF0173 protein PF0020.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: SYE_KORCO
Sequence: MEDVKELIVRLAAENALKYGKADTKAVIGKILYMRPDLKQNVRELIPLVEEAVRAVNEMPKEALEGIVGEVKKEKKEEVRKWPDLPKAERGKVVTRVAPEPNGYPTLGHAKGLLVPFIYARLYDGKFLLRFEDTNPRVERLEYYEAIRNEFSRLLEACEEELGLSPGRWDEEIIESYHLEEMYSLAKKLIEAGKAYVCTCPAAEVRKRRKLGISCDHRDQPIEKNLELWEKMLNGGFREGEAHLRLKTDMSHPNVTMRDPGIFRVIEAEHPIHGDKYRVYPVYDFSVSVMDSLTGVTHAFRSKEFEPHVDVQRHIVRALGLREYEMIQFGRITVEGIPLSKRYIRPLVESGILEGWDDPRIPTLRGLFRRGINPRAIVRFFYELGPSKVDATVNMEAIASINRKILDPIAERYMFVPNPIKAKIEGLTPPVIAQVEVHPDSKRKREIRLDESEVFIASSDLEGLKPGDELRLRGLVNVTIRSVNPDEVSLRVSEEQRVKGVKIIQWAPVRNGVPARLFVPESPYSFRMLGGYGEPALRGIKEGEIVQFVRVGFARLDRRDPLTFILSHD
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COL13_CAEEL
Sequence: MSEDLKQIAQETESLRKVAFFGIAVSTIATLTAIIAVPMLYNYMQHVQSSLQSEVEFCQHRSNGLWDEYKRFQGVSGVEGRIKRDAYHRSLGVSGASRKARRQSYGNDAAVGGFGGSSGGSCCSCGSGAAGPAGSPGQDGAPGNDGAPGAPGNPGQDASEDQTAGPDSFCFDCPAGPPGPSGAPGQKGPSGAPGAPGQSGGAALPGPPGPAGPPGPAGQPGSNGNAGAPGAPGQVVDVPGTPGPAGPPGSPGPAGAPGQPGQAGSSQPGGPGPQGDAGAPGAPGAPGQAGAPGQDGESGSEGACDHCPPPRTAPGY
What is the function of this protein?
Nematode cuticles are composed largely of collagen-like proteins.  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
What are the official names of this protein?
Cuticle collagen 13.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
Protein: SYE2_EHRRG
Sequence: MLNHVVTRFAPSPTGHLHLGGARTALFNWLYAKHNNGKFLLRIEDTDSKRSSKELIDSIINSMIWLNIQHDGEIILQSSRISRHIEIANQLILNDKAYYCYCSEEEINLEKEQYTKKGLHYKHNCIWKNRKPPTGNCSKVIRLHSDTEGITEFKDKVYGTIAVNNVQLDDMVLLRSNNTPTYLLSVVVDDYDMGITHIIRGTDHLTNTARQLLIYNALGWKPPEFAHIPLIHDENGNKLSKRHHALGIHEYKNAGILPEALVNYLLRMGWSHGNDELITIDEAIRWFSIDKVGQSPAGLDSKKLEFLNNHYINTTNNATIIEMIIPIIEKTIGYKVNTEKIGYLLNGINELKKRTKNLVNLANESLFYVEDIPISFDQESLIIIKSNHDILSILYDNLSKVLNDDWNNSTLTSMIKNIVKDYNTKIHNIYHCLRASIIGRINAPSIIDIMVNFQREECLNRIKYARDMVK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y628_AQUAE
Sequence: MKKKFAVIGSILALAPFALATNGDNMIGIGPASRGMGGIGTGMPVGPIDSIFRNPAWMSYFNTKRFFLSFGGILFMPNVKVSSKMFMDFEPRNSGGGGYFQTNGRVKSDADTFIVPEVGIVHKVN
What are the official names of this protein?
Uncharacterized protein aq_628.
Protein: KAT6B_MACFA
Sequence: MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGTFPKSTKESRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYGSLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVTSDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYHHHERHISIKAISRATGMCPHDIATTLQHLHMIDKRDGGFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEVLSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEEDEEEEDEEEEEEEEEDEEEEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSRNLKEGSKDNPEPLKCKQAWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPLEPDEQVTVEEQKETSEGKTSPTPISIEEEAKEAGEALLPQEENRRQETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEGEEEEEEGGNVEKDPDGAKSQEKEEPEISPEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENEEAFLDLNVQPSHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIPETGNANIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASKGHVSMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTLTMQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTPQYPMQMQMGMMGTQPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR
What is the function of this protein?
Histone acetyltransferase which may be involved in both positive and negative regulation of transcription.  Required for RUNX2-dependent transcriptional activation.  May be involved in cerebral cortex development.  Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
What are the official names of this protein?
Histone acetyltransferase KAT6B, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4, MYST-4.
What is the protein family that this protein belongs to?
Belongs to the MYST (SAS/MOZ) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS3_DESVH
Sequence: MTAFVPDFGKAGGLVPAIAQDADTGEVLMMAWMNAEAFEMTLKTGEAHYFSRSRGRLWHKGGTSGHTQHIRAVRLDCDSDTILLLVEQRGGAACHEGYRSCFYREMKDGEVSICSPKVFDPKEVYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIO_BOSTR
Sequence: MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGSWGQPHGGGWGQPHGGSWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGTHGQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMNRPLIHFGNDYEDRYYRENMHRYPNQVYYRPVDQYSNQNNFVRDCVNITVKEHTVTTTTKGENFTETDIKMMERVVEQMCITQYQTESQAYYQRGASVVLFSSPPVVLLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: IOVO_POLNP
Sequence: VDCSEYPQPACTTERRPVCGSNNKTYSNKCNFCNAVVKSNGTLTVSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.