PharMolix/UniProtQA huggingface dataset:
Protein: METXS_PSEU2
Sequence: MPTVFPHDSVGLVTPQTAHFSEPLALACGRSLPAYDLIYETYGQLNAARSNAVLICHALSGHHHAAGFHSADDRKPGWWDSCIGPGKPIDTTKFFVVSLNNLGGCNGSTGPSSIDPDTGKPFGANFPVVTVEDWVNSQARLADLLGIDTWAAVIGGSLGGMQALQWTISYPNRVRHCLAIASAPKLSAQNIAFNEVARQAILTDPEFHGGSFQERGVIPKRGLMLARMVGHITYLSDDSMGEKFGRGLKSEKLNYDFHSVEFQVESYLRYQGEEFSGRFDANTYLLMTKALDYFDPAANFNDDLAKTFANATARFCVMSFTTDWRFSPARSRELVDALMAARKDVCYLEIDAPQGHDAFLIPIPRYLQAFGNYMNRISL
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADD_METVS
Sequence: MILVKDAIINGKKQDLLVEGNIIKKIGNVPISEVSKDETEIIDGKNCILIPGLVNTHTHIPMSLFRGVADDIPLMEWLSGHIWPMESKLNEKIVYAGTLLGAVEMIKSGTTAFNDMYFFLDSIIKAVDETGIRSTIAYGMIDLFNEEKREKELKSAKKSIEMIKKLNNSRITGALGPHAPYTCSKELLESTNALAREYNVPIHIHMNETVDEINQVLEKTKMRPFEYLNSFGFFDNVTTVCAHCVHLNDSEIKIIKEKNIFVAHNPISNLKLASGVSPVAKLLENEVNITLGTDGCGSNNSLNLFEEMKTAALIHKGVNLNPVLVTAKEAFEFGTLNGAKALNINSGEIKEGKLADFALINVKKPYLTPRENIESHLVYSFNGAVDSVVIDGKLTLKDGKMVTIDEEKVYELAEEAYLELTK
What is the function of this protein?
Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'-methylthioadenosine, to produce the inosine analogs.  Can also deaminate adenosine.  The preferred substrate for this enzyme is 5'-deoxyadenosine, but all these substrates are efficiently deaminated.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  May also be involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens.
What are the official names of this protein?
5'-deoxyadenosine deaminase, 5'-dA deaminase, 5'-methylthioadenosine deaminase, MTA deaminase, Adenosine deaminase, S-adenosylhomocysteine deaminase, SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: AROE_ACICJ
Sequence: MILSGHARLAGVIGYPVAHSRSPRLHGTWLERHGIDGAYLPLAIAPDDFAACVAALAKMGFAGANVTIPHKEAAFAVCDRVADSARRAGAVNTLVFTPTGIEGANTDGSGFLANLRAHGVNPAAGPALVLGAGGAARAIATALQDAGAVVTLCNRSPERAVALARDFGLVHIPWEARSAALADHALVVNTTSLGMAGHNPLELDLARAAPGMAVADIVYVPLETPLLAAARARGLVAVEGLGMLLHQAVPGFAAWFGVTPVVDDALYRAVAADLMG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: ARLY_NITWN
Sequence: MSNKMWGGRFGEGPDAIMEEINVSIDVDRHLYAQDIAASKVHAEMLAAQGIIAANDAKKIGKGLDTILSEIRDDSFDFKRALEDIHMNVESRLGELIGPSAGRLHTARSRNDQVATDFRLYVRDIIDETDNALATFQHTLATRALEFAGTVMPGFTHLQTAQPVTFGHHLLAYVEMAARDRGRFADARRRLNESPLGAAALAGTSFPIDRHATAKGLGFDRPMANSLDAVSDRDFVLETLSAAAIASTHLSRFAEEMVIWTSPLVGLVRLSDKFTTGSSIMPQKRNPDAAELVRAKTGRVVGALTGLLVVMKGLPLAYQKDMQEDKQGAMEAFSALSLAIRAMTGMVADLVPDEARMKAAAGDGYATATDLADWLVRTLKMPFRDAHHVTGRIVAAASKQGVALHELPLSAMQAVEPRITRDALAVLSVEASVKSRTSYGGTAPKNVRAQAKAWLRRLEKKRTPD
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_ROSDO
Sequence: MSDEKICVGAIAGAYGVRGELRIKSFCATAEDIETYSPLTSEDGQRHFHLALVRPIKGGFVARIAEVSSKEEADALKGVQLFALRDQLPSLPDDEYYYTDLIGLQVLDTGGELLGSVKTVADHGAGDILEVQRPGTSETILLPFTRAVVPTVDLLAGKLIADPPEGAL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDX19_DROME
Sequence: MGDWAKKSEDQEVSKLVDKLNLDSKSGEETDFDVADPAETSLLIKILGKGLVNTKLSLDLQQKNPNSPLHSVKTFEALHLKASLLKGIYAMGFNTPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVNVCLNHPQVLCLSPTYELAIQTGEVAARMGQFCREIKLRFAVRGEEVDRSKKIEEHILIGTPGKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCIRIHKMLNPHCQMLFFSATYGKEVMDFARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRTAAWLAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQLQVVVNFDLPVDLDGMADCETYLHRIGRTGRFGKSGIAINLITDEKTMKVCSDIEKHFNKKIEVLNTDSADDIEKIGT
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA export from the nucleus.
What are the official names of this protein?
DEAD-box helicase Dbp80.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Note=Associates with the nuclear pore complex cytoplasmic fibrils.
Protein: MSHB_STRBB
Sequence: MTPVLPARRLLLVHAHPDDESINNGATMAKYAAEGAQVTLVTCTLGEEGEIIPPALAHLAADRDDALGPHRIGELAVAMKALGVSDHRFLGGPGRYRDSGMMGAPQNDRPECFWRAEVDDAAAHLAEVVREVRPQVLVTYDPHGGYGHPDHIQAHRVAMRAAELAAEPAYRRDLGDPHQIAKIYWNCVPRSELEEGFARLRAQGDGAPFPRIASAGDVPGVVDDARVTATVDGAGYAEAKAEAMRAHATQIAVDGPFFALSNDLGQPLSAMEHYLLVRGQAVAASGSDRGREDDLFAGVSV
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: TOTF_DROME
Sequence: MKTVILFGFLLALLGYLEAEHAQSDPEFTAKARQMLAVFGNSEVDRYTKSRNLPALIEFYEKYSSRLPLTVQDRTYANNVIRRYRAHNNQQVDGVPAQGGVGVVFALLLPFAVSIVEGIAKAIRE
What is the function of this protein?
A humoral factor that may play a role in stress tolerance.
What are the official names of this protein?
Protein Turandot F.
What is the protein family that this protein belongs to?
Belongs to the Turandot family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECO_DESAL
Sequence: MPPVTTSAVILRSIEYGDFDLIVTFFTQAQGKRAALAKNARKSFKRFGGALELFSKVSIVYAHGKKKGGLPLLSESNLEQHFSNIRMDIHKTALASLWAETIYSWAEEEHAQEEIFQLLIRSLENLDNEKVDRDKVNILFLLRFLALAGLSPSLDQCVLCCRSLEDWGQGGICFDHARGGIVCPKCGVCLAPGPVLSVGAVKQLLWLNKGDLAAAGRMKLSREAMDRGRDLLESFLAYHLGKEPKSLRFLKDLRRRHF
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PRVB_GADMO
Sequence: MAFAGILNDADITAALAACKAEGSFDHKAFFTKVGLAAKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKVFLKAGDSDGDGKIGVDEFGAMIKA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: RNPH_PSEP1
Sequence: MKRPSGRVADQLRSIRITRNYTKHAEGSVLVEFGDTKVICTVSVENGVPRFLKGQGQGWLTAEYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLRAALDMSKLGDITLYVDCDVIQADGGTRTASITGAMVALCDALAVIKKRGGLKGGNPLKHMIAAVSVGMYQGEAVLDLDYLEDSAAETDLNVVMTSAGGFIEVQGTAEGAPFQPEDFNAMLALAQKGMNEIFELQQAALAD
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: CDPAS_SULIL
Sequence: MSIAYDLLLSILIYLPAFVANGSGPFIKRGTPIDFGKNFVDGRRLFGDGKTFEGLIVALTFGTTVGVIISKFFTAEWTLISFLESLFAMIGDMIGAFIKRRLGIPRGGRVLGLDQLDFVLGASLILVLMRVNITWYQFLFICGLAFFLHQGTNYVAYLLKIKNVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISL1_MESAU
Sequence: MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA
What is the function of this protein?
DNA-binding transcriptional activator.  Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes.  Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation.  Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina.  Involved in the specification of motor neurons in cooperation with LHX3 and LDB1 (By similarity).  Binds to insulin gene enhancer sequences (By similarity).  Essential for heart development.  Marker of one progenitor cell population that give rise to the outflow tract, right ventricle, a subset of left ventricular cells, and a large number of atrial cells as well, its function is required for these progenitors to contribute to the heart.  Controls the expression of FGF and BMP growth factors in this cell population and is required for proliferation and survival of cells within pharyngeal foregut endoderm and adjacent splanchnic mesoderm as well as for migration of cardiac progenitors into the heart (By similarity).
What are the official names of this protein?
Insulin gene enhancer protein ISL-1, Islet-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASSY_MYCA1
Sequence: MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEDMEVIRQRALDCGAVEAVVVDARDEFAEGYCLPTIRNNALYMDRYPLVSAISRPLIVKHLVAAAREHGGSIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDVYAYTEDPTLNWSTPDEVIVGFERGVPVSIDGKPVSVLGAIEELNARAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRHTDQRWAELVYDGLWYSPLKAALESFVDKTQEHVTGEIRMVLHGGHIAVNGRRSAESLYDFNLATYDEGDSFDQSAAKGFVYVHGLSSKIASRRDQR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_ACIBT
Sequence: MAIERTLSIVKPDAVSKNHIGEIFARFEKAGLKIVATKMKHLSQADAEGFYAEHKERGFFGDLVAFMTSGPVVVSVLEGENAVLAHREILGATNPKEAAPGTIRADFAVSIDENAAHGSDSVASAEREIAYFFADNEICPRTR
What is the function of this protein?
(Microbial infection) Catalyzes the phosphorylation of dZDP to dZTP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SX19B_DANRE
Sequence: MYSMMEHELKTAGPPHTLQHSPGMSPPGSGVGNAHHVSKTACPPGVDPMDKVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTDVEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKALMKKDNPVGKYPLAAGNLLASAVAQGQGGSPRMDGYGWGHAGGYMGMQGDALGYPQQLHRYDLSALQYPAAQPYMNSASSYSQMSYSSSPQQPSPVMSMVKPEPLSHSPTGVPNHHRGAFQGDLRDMISMYIPGGDTSESSNQRAYPGVQQHYLGGTVPLTHI
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Transcription factor Sox-19b, Protein sox-31.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUB56_ARATH
Sequence: MTPSSSGLEQSEIDAIQELEQTSRNDTLLKYHDICIDEGVIEQDVDMSCFSANSVGEWIVELIYQNNIKKLIMGATADSHYSEGMVHITPTKADYVIQHAPHCCNIWLVCNGNLIQTREGRFEHAGSAYSSSSSLHSIDSALIPYGGAGRAERVTEPHALSSSEEQSARGIEKMYYEEQRRRLEIEELKREKEQRDKMRRVREEALSSSSGVTKILYNEEVMRRREVEAELNRAKAEIEDMKRVQIELKEQHYADCRLLEKERDEAIKTTEELLRALEKGESSIPLQWSVSIEPPQCFICPISKDIMQNPHVAADGYTYEADEFRRWLNHGGEKSPMTNLRLENRNLIPNLVLRSAIKDWLQQHP
What is the function of this protein?
Functions as an E3 ubiquitin ligase.
What are the official names of this protein?
U-box domain-containing protein 56, Plant U-box protein 56, RING-type E3 ubiquitin transferase PUB56.
Protein: APT_KLEP3
Sequence: MTATAQQLEYLKNSIQSIEDYPKPGILFRDVTSLLEDPKAYALSIELLTERYKDAGITKVVGTEARGFLFGAPVALALGVGFVPVRKPRKLPRETIAESYELEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIDATVKLIRRLGGEVHDAAFIINLFDLGGEQRLEKLGIHCYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1124_ARATH
Sequence: MRKVHLFLVLVHFIYISTSRSDSISERDILLQFKGSISDDPYNSLASWVSDGDLCNSFNGITCNPQGFVDKIVLWNTSLAGTLAPGLSNLKFIRVLNLFGNRFTGNLPLDYFKLQTLWTINVSSNALSGPIPEFISELSSLRFLDLSKNGFTGEIPVSLFKFCDKTKFVSLAHNNIFGSIPASIVNCNNLVGFDFSYNNLKGVLPPRICDIPVLEYISVRNNLLSGDVSEEIQKCQRLILVDLGSNLFHGLAPFAVLTFKNITYFNVSWNRFGGEIGEIVDCSESLEFLDASSNELTGRIPTGVMGCKSLKLLDLESNKLNGSIPGSIGKMESLSVIRLGNNSIDGVIPRDIGSLEFLQVLNLHNLNLIGEVPEDISNCRVLLELDVSGNDLEGKISKKLLNLTNIKILDLHRNRLNGSIPPELGNLSKVQFLDLSQNSLSGPIPSSLGSLNTLTHFNVSYNNLSGVIPPVPMIQAFGSSAFSNNPFLCGDPLVTPCNSRGAAAKSRNSDALSISVIIVIIAAAVILFGVCIVLALNLRARKRRKDEEILTVETTPLASSIDSSGVIIGKLVLFSKNLPSKYEDWEAGTKALLDKENIIGMGSIGSVYRASFEGGVSIAVKKLETLGRIRNQEEFEQEIGRLGGLQHPNLSSFQGYYFSSTMQLILSEFVPNGSLYDNLHLRIFPGTSSSYGNTDLNWHRRFQIALGTAKALSFLHNDCKPAILHLNVKSTNILLDERYEAKLSDYGLEKFLPVMDSFGLTKKFHNAVGYIAPELAQQSLRASEKCDVYSYGVVLLELVTGRKPVESPSENQVLILRDYVRDLLETGSASDCFDRRLREFEENELIQVMKLGLLCTSENPLKRPSMAEVVQVLESIRNGFGS
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At1g12460.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TAPT1_XENLA
Sequence: MADAAMSGEEKEEDGGKRTTAATPAETLGFYEPSDGSRVETKKRSLSDLSLLRFISAELTRGYFLENNEAKYKERREKVYTCLRIPRELEKLMVFGFFLCLDAFLYVFTLLPLRVLLALIRFLTLPCCGLSDGRVLQPAQVCDVLKGVILVICYFIMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHLGVIPHFFMAVLYVILHAILILVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYVLLLIVCLRNMEQFSWNPDHLWVLFPDVCMVIASEIAVDVVKHAFITKFNDITADVYSEYRASLAFELVSSRQKNACTDYSDSVSRRMGFIPLPLAVLLIRVVTSSVKVQGILAYSCVVLFYFGLITLKVLNSIVLLGKSCQYIKDANMEEKLFQPPTCQPGKTPKKAQNKSKPNQGHPPDETANTSVTSQPTKAASTAQLLVESNSDKLLTTPDAEEKDISGDNSELKQKQADKDLLDIDRFTICGNRID
What is the function of this protein?
Plays a role in primary cilia formation.  Involved in cartilage and bone development.  May play a role in the differentiation of cranial neural crest cells.  May act as a downstream effector of hoxc8 during development.
What are the official names of this protein?
Transmembrane anterior posterior transformation protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TAPT1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Membrane; Multi-pass membrane protein.
Protein: GLPD2_MYCBO
Sequence: MSNPIQAPDGGQGWPAAALGPAQRAVAWKRLGTEQFDVVVIGGGVVGSGCALDAATRGLKVALVEARDLASGTSSRSSKMFHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPLPFLFPLTKRWWERPYIAAGIFLYDRLGGAKSVPAQRHFTRAGALRLSPGLKRSSLIGGIRYYDTVVDDARHTMTVARTAAHYGAVVRCSTQVVALLREGDRVIGVGVRDSENGAVAEVRGHVVVNATGVWTDEIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAMILRTEKSVMFVIPWGSHWIIGTTDTDWNLDLAHPAATKADIDYILGTVNAVLATPLTHADIDGVYAGLRPLLAGESDDTSKLSREHAVAVPAAGLVAIAGGKYTTYRVMAADAIDAAVQFIPARVAPSITEKVSLLGADGYFALVNQAEHVGALQGLHPYRVRHLLDRYGSLISDVLAMAASDPSLLSPITEAPGYLKVEAAYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPVLGWTAADIDREVANYMARVEAEVLSQAQPDDVSADMLRASAPEARAEILEPVPLD
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASF1_CANAL
Sequence: MSIVSLTGIEVLNNPAKFTDPYEFQITFECLEPLKEDLEWKLTYVGSSDSLDHDQELDSILVGPVPVGINSFLFKADAPSPELIPASELVSVTVIILSCSYNDKEFVRVGYYVNNEYDTEELRENPPAKVAIDHVVRNILAEKPRVTRFNIVWDNEEGADEYPPEQPEDEEEEEEEEEEGEEEEEDEDEEDDDDDEDLNGDAVVDLEKEEISTPRDNDEDIEIDIASESEVEEGGVEEEAKVNTPKD
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
What are the official names of this protein?
Histone chaperone ASF1, Anti-silencing function protein 1.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURB_BURMS
Sequence: MSRPDSAVSLLPDYSLRAHNTFGFDARARVAARIGSPGQFASLARDPRVAGLDRLVLGGGSNVVFTRDFDGLVLLDEIRGRALVREDDGAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAPIQNIGAYGLEMKEHFASLRAVDLATGELVEFDAARCAFGYRDSFFKRDGRGRFAIVAVTFRLPKAWTPRIGYADVARELAARGIDARAARARDVFDAVVAIRRAKLPDPLALGNAGSFFKNPVIDAQAFAALRAREPDIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHERQALVLVNLGGASGADVLALAHAIRRDVLGRFGVELEMEPVCL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CS13A_LISSS
Sequence: MWISIKTLIHHLGVLFFCDYMYNRREKKIIEVKTMRITKVEVDRKKVLISRDKNGGKLVYENEMQDNTEQIMHHKKSSFYKSVVNKTICRPEQKQMKKLVHGLLQENSQEKIKVSDVTKLNISNFLNHRFKKSLYYFPENSPDKSEEYRIEINLSQLLEDSLKKQQGTFICWESFSKDMELYINWAENYISSKTKLIKKSIRNNRIQSTESRSGQLMDRYMKDILNKNKPFDIQSVSEKYQLEKLTSALKATFKEAKKNDKEINYKLKSTLQNHERQIIEELKENSELNQFNIEIRKHLETYFPIKKTNRKVGDIRNLEIGEIQKIVNHRLKNKIVQRILQEGKLASYEIESTVNSNSLQKIKIEEAFALKFINACLFASNNLRNMVYPVCKKDILMIGEFKNSFKEIKHKKFIRQWSQFFSQEITVDDIELASWGLRGAIAPIRNEIIHLKKHSWKKFFNNPTFKVKKSKIINGKTKDVTSEFLYKETLFKDYFYSELDSVPELIINKMESSKILDYYSSDQLNQVFTIPNFELSLLTSAVPFAPSFKRVYLKGFDYQNQDEAQPDYNLKLNIYNEKAFNSEAFQAQYSLFKMVYYQVFLPQFTTNNDLFKSSVDFILTLNKERKGYAKAFQDIRKMNKDEKPSEYMSYIQSQLMLYQKKQEEKEKINHFEKFINQVFIKGFNSFIEKNRLTYICHPTKNTVPENDNIEIPFHTDMDDSNIAFWLMCKLLDAKQLSELRNEMIKFSCSLQSTEEISTFTKAREVIGLALLNGEKGCNDWKELFDDKEAWKKNMSLYVSEELLQSLPYTQEDGQTPVINRSIDLVKKYGTETILEKLFSSSDDYKVSAKDIAKLHEYDVTEKIAQQESLHKQWIEKPGLARDSAWTKKYQNVINDISNYQWAKTKVELTQVRHLHQLTIDLLSRLAGYMSIADRDFQFSSNYILERENSEYRVTSWILLSENKNKNKYNDYELYNLKNASIKVSSKNDPQLKVDLKQLRLTLEYLELFDNRLKEKRNNISHFNYLNGQLGNSILELFDDARDVLSYDRKLKNAVSKSLKEILSSHGMEVTFKPLYQTNHHLKIDKLQPKKIHHLGEKSTVSSNQVSNEYCQLVRTLLTMK
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  Unlike many single-component effectors, this CRISPR-Cas system targets RNA (By similarity).  CRISPR clusters are transcribed from pre-CRISPR RNA (crRNA) and processed into crRNA by this protein (PubMed:27669025).
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas13a, CRISPR-associated endoribonuclease C2c2, EndoRNase, LseC2c2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas13a family.
Protein: PYRE_HALWD
Sequence: MTIPQSPTTEDIVAALRNADAVQYGEFELSHGGTSAYYIDKYLFETDPKCLQIIASAFADRINETTLAGVALGAVPLVAVTSTVAGQPYVVVRKKAKKYGTGNRIEGRLNEDEEVVVLEDIATTGTSAVEAVNALRDVGATVERVFVVVDRQEGAREQLESNNVEMEALVTATDLLVDDENV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PSA72_DROME
Sequence: MSSRYGRALTIFSPDGHLLQVEYAQEAVRKGSTAVGVRGANCVVLGVEKSSVSEMQEDRTVRKISMLDRHVALAFAGLTADARILINRGQVECQSHRLNFENQVTLEYITRYLAQLKQKYTQCNGRRPFGISCLIGGIDADGSARLFHTEPSGIFHEYKATATGRWANTVREFFEKAYSDHEVTTKCDAIKLAMRALLEVTQMSQMRLEVAVLENGKPMKMLDSVVISEIVKIVQNEKELQAKAHKMKR
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-7-1A, Testis-specific alpha4-t1 proteasome subunit, Testis-specific proteasome 28 kDa subunit 1A.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECA_WOLTR
Sequence: MASNPEEKSNDRQKALDNAISQIEKAFGKGAIMKLKQNPVEKIDTISTGSIALDSALGVGGLPKGRIVEIFGPESSGKTTLALHVIAEAQKKGGLCAFIDAEHALDVMYARKLGVNTDNLVISQPDTGEQALHIVEYLVCSSAVDVIVVDSVAALTPRAEIEGDMGDQHVGLQARLLSHGLRKLTSAVSKANCILIFINQIRMKIGVVYGNPETTTGGNALKFYTSVRLDIRKVGAIKDKESIKGNETRVKVVKNKVAPPFREAKFDIMYNEGVSKLGEIIDIGAKLGVLEKAGAYYSYNNTRLGQGRENVKNYFKANKEVANEVEAKIRDLLGNSDNSITMEEESRQLLEEAVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.