PharMolix/UniProtQA huggingface dataset:
Protein: NUDC_MYCTA
Sequence: MTNVSGVDFQLRSVPLLSRVGADRADRLRTDMEAAAAGWPGAALLRVDSRNRVLVANGRVLLGAAIELADKPPPEAVFLGRVEGGRHVWAVRAALQPIADPDIPAEAVDLRGLGRIMDDTSSQLVSSASALLNWHDNARFSALDGAPTKPARAGWSRVNPITGHEEFPRIDPAVICLVHDGADRAVLARQAAWPERMFSLLAGFVEAGESFEVCVAREIREEIGLTVRDVRYLGSQQWPFPRSLMVGFHALGDPDEEFSFSDGEIAEAAWFTRDEVRAALAAGDWSSASESKLLLPGSISIARVIIESWAACE
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: SMP_SHIFL
Sequence: MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQLEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQLTDESRILDAGVYDEQGDLIARSGESVEVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDNTTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEESEKKE
What are the official names of this protein?
Protein Smp.
What is the protein family that this protein belongs to?
Belongs to the Smp family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYA_NEIMF
Sequence: MKTSELRQKFLKFFETKGHTVVRSSSLVPHDDPTLLFTNAGMNQFKDVFLGFDKRPYSRATTAQKCVRAGGKHNDLENVGYTARHHTFFEMMGNFSFGDYFKRDAIHFAWEFLTSPEWLNIPKDKLLATVYAEDDEAYNIWLNEIGMPSERIVRIGDNKGAKYASDNFWQMGDTGPCGPCSEIFYDHGEEIWGGIPGSPEEDGDRWIEIWNCVFMQFNRDEQGNMNPLPKPSVDTGMGLERMAAVMQHVHSNYEIDLFQDLLKAVARETGAAFSMEEPSLKVIADHIRSCSFLIADGVLPSNEGRGYVLRRIIRRAVRHGYKLGQSKPFFHKLVADLVKEMGDAYPELKEKQVQIEEALKNEESRFAQTLETGMALLENALAKGSKKLDGEIIFKLYDTYGFPYDLTADICRERNIELDEAGFEREMEAQRARARAAQSFKANAQLPYDGQDTEFKGYSERQTESKVLALYKDGEQVDELNEGDSGAVVIDFTPFYAESGGQVGDVGYIFSGENRFEVRDTQKIKAAVFGQFGVQTSGRLKVGDSVTAKVDDEIRNANMRNHSATHLMHKALRDVLGRHVEQKGSLVTAESTRFDISHPQAVTAEEIAEVERRVNEAVLANVAVNAAIMSMEDAQKTGAMMLFGEKYGDEVRVLQMGGFSTELCGGTHVSRTGDIGLFKIISEGGIAAGVRRIEAITGLNALKWAQEQERLVKDIIAETKAQTEKDVLAKIQAGAAHAKALEKELARAKAELAVHAGAKLLDDAKDLGAAKLVAAQIEADAAALREIVTDLTGKSDNAVILLAAVNDGKVSLCAGVSKALTGKVKAGDLVKFAAEQVGGKGGGRPDLAQAGGTDAGKLPAVLDSVKDWVGAKLV
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_STRGC
Sequence: MYEYFKGIISKITAKYIVLEVNSIGYILHVANPYAYSGHLHQEAKVYVHQVVREDAELLYGFATEEEKQLFLSLISVSGIGPVSALAIIAADDNAGLVQAIEQKNITYLTKFPKIGKKTAQQMVLDLEGKVVAADGLAESKAPVQTVDNQELEEAMEAMLALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: AMPP2_COCPS
Sequence: MAGSNTLSSSEHGDDPRGHSYSIHIQTRGTTLDKYPAKQHARNVARQLGLTDGLIYLMSQSTRTLEDSDQPQPFRQRRYFFYLSGVDEPDCHLTFDIKSDILTLYVPHYDLRKAIWVGPTLRPSEAMMRYDLNAAKTYDELSKNIRTWASKRMSPVIYILHEGQKPNINAHFLAFNHEDLLPAMDACREIKDEHEIDLIRRANEISASAHIEVLLGIRNMQNEAEIHGKFLDTCVSQGARNQSYEIIAASGENAAILHYTKNNEPLDDRQLVCLDAGAEWNCYASDVTRTFPRRPYWPSCESANIYSVVQRMQEECINGLKEGVRYLDLHILAHRIAIEELLSLGILKGGSTEEILQSGASLVFFPHGLGHHVGLEVHDVSPTPLMAFSLDKYKGLPLLSCRPPCTLSAPYLKAGMVVTVEPGIYFSRPALKDARRKPLSKYIDMDVVQKYIPVGGVRIEDDVLVTRDGFENLTKAPKGREMLKTIR
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase CPSG_02684, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: TF2B_METJA
Sequence: MVWLMEALKTKENETTKEKKLTTKVEKSEKKEENVREEEIVCPICGSKEVVKDYERAEIVCAKCGCVIKEKLFDIGPEWRAFDHEQKIKRCRVGAPMTYSVDYNEPIIIKENGEIKVVKIGELIDKIIENSENIRREGILEIAKCKGIEVIAFNSNYKFKFMPVSEVSRHPVSEMFEIVVEGNKKVRVTRSHSVFTIRDNEVVPIRVDELKVGDILVLAKELPNIEEDIEIDKKFSKILGYIIAEGYYDDKKIVLSYDYNEKEFINETIDYFKSLNSDITIYSKDLNIQIEVKNKKIINLLKKLRVKNKRIPSIIFKSPYEIKKSFIDGIFNGKDAKVFVSKELAEDVIFLLLQIKENATINKKSINDIEVYEVRRITNIYTNRKLEKLINSDFIFLKIKEINKVEPTSGYAYDLTVPNAENFVAGFGGFVLHNTIHDKGLSTVIDWRNKDSYGKDLSANKRAQLYRLRKWQRRIRVSDAAERNLAFALSELDRITSKLGLPRHVRENAAIIYRGAVEKGLIRGRSIEGVVAAAIYAACRRCRVPRTLDEIAEASRVDRKEIGRTYRFLARELNIKLTPTNPIDYVPRFASELGLPGEVESKAIQILQQAAEKGLTSGRGPTGVAAAAIYIASVLLGCRRTQREVAEVAGVTEVTIRNRYKELTEHLDIDVTL
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: TRUA_LEUMM
Sequence: MPRYKAVIAYDGAEFFGFQLQTKNGVESVRTVQGELNKVINKMAKNPSPQIKVVGASRTDTGVHAFGQVVHFDLPFNIDPEGVRKGMNTLLPFDVVVNHVEHVSDDFHARFNTHSKRYIYRVSTTDYKDPFKRKYTGHFHWKLDINRIKAALPDLLGEHDFASFAASGNETATTIRLITRADVDEKPEEHEIVFTFEGNAFLYNQIRIMVGVLLEIGTGKRPVHDIVRLIEVKDREQARYTAPASGLYLDEIDYN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MNMA_RHIEC
Sequence: MSAQNLAPPLNTLDFDKKPEETRVVVAMSGGVDSSVVAGLLKQQGYDVLGITLQLYDHGAAVHRAGSCCAGQDIDDARHVCETLGIPHYVLDYEKRFRETVINPFAESYVAGETPIPCVSCNQTVKFADLLATAKELGADALATGHYIRSRPNPSSEHPGRRALFRPADADRDQSYFLFATTQEQIDYLRFPLGGLPKAETRRLAEEMGLVVAKKADSQDICFVPQGKYSDIITKLKPNAALAGEIVHLDGRVLGSHEGILHFTIGQRRGIGIATGEPLYVVYLDARSRRVIVGPKEALETHRVYLRDVNWLGDETLAEAASGEGFACYAKVRSTRAPAPAVLHVDATGTYVDLTIGEAGIAPGQACALYSAPGDDARVFGGGFIERSEREPSAEASLKALLASPVAA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTD_YERPP
Sequence: MVTQATSVRWQLWIVAFGFFMQTLDTTIVNTALPSIAASLGENPLRMQSVIVSYVLTVAVMLPASGWLADRIGVKWVFFSAIILFTFGSLMCAQSATLNELILSRVLQGVGGAMMVPVGRLTVMKIVPREQYMAAMAFVTLPGQIGPLVGPALGGFLVEFASWHWIFLINLPVGVIGALATLLLMPNHKMSTRRFDISGFIMLAIGMATLTLALDGHTGLGLSPLAIAGLILCGVIALGSYWWHALGNRFALFSLHLFKNKIYTLGLVGSMSARIGSGMLPFMTPIFLQIGLGFSPFHAGLMMIPMIIGSMGMKRIIVQVVNRFGYRRVLVNATLLLAVVSLSLPLVAIMGWTLLMPVVLFFQGMLNALRFSTMNTLTLKTLPDRLASSGNSLLSMAMQLSMSIGVSTAGILLGTFAHHQVATNTPATHSAFLYSYLCMAIIIALPALIFNRVPPDTGANRHLAR
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y534_HISS2
Sequence: MSDIAITICILALVAVIGLWIGHWKIRGVGLGIGGVLFGGIIVAHFMNQNGLKLDAHTLHFIQEFGLILFVYTIGIQVGPGFFASLLSAGLKLNGLATLIVVLGAVSVFVLYKVVNVDLDIILGIYSGAVTNTPSLGAGQQILTELGIENANSTMGMAYAMAYPFGICGILLSMWLIRLFFKIKVEEEEKQFQKASGQDKESLTTVNVKVTNPNLSGLRLIDIPGFDNKDVVCSRLKRQENISVPSADTIIAIDDVLHLVGEINALKKMKLVIGEEIDMPMTHLAGDLRSERIVVTNEKVLGKRIKHLGIHKKYGVVISRLNRAGVELVPTANTALQFGDVLHIVGRSDTIGNATSIIGNAQQKLQQVQMLPVFIGIGLGVLLGSIPFYIPGFPVALKLGLAGGPLVVALILARIGSVGKLYWFMPPSANLALREIGIVLFLAVVGLKSGGGFVDTLVNGQGLEWMGYGMFITFIPLMITGIIARLYMKLNYLSLCGLLAGSMTDPPALAFANAIKEDSGIAALSYATVYPLSMFLRIMSPQLLAILLWTAM
What are the official names of this protein?
Putative transport protein HSM_0534.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LOC1_CANGA
Sequence: MGSIKKTKGKSQSTKRVVTPEVFADQQARNQLANAPNLTEKSERRKANKLQVKKEQARARLYGKKKKESTYSEKDLDLPSLNKAVNPGVKLRRGKKGKKFIDDHDSLTLHRLIKTIGDKYDDITESKLEKDRRLEVIRELKRQEIERKEAAKQSQLEEKKDELKKKSSIARSMRRKNRRDQERDLHTTSNDKVQRKKKSVSFA
What is the function of this protein?
Required for efficient assembly and nuclear export of the 60S ribosomal subunit.
What are the official names of this protein?
60S ribosomal subunit assembly/export protein LOC1.
What is the protein family that this protein belongs to?
Belongs to the LOC1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: M231_CONAE
Sequence: MMSKLGVLLTICMLLFPLTALPLDGDQPADRPAERMQDDFISEQHPLFNPIKRCCDWPCTIGCVPCCK
What are the official names of this protein?
Conotoxin ArMMSK-01.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CSRP1_RAT
Sequence: MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKSCYGKKYGPKGYGYGQGAGTLSMDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCPRCSQAVYAAEKVIGAGKSWHKSCFRCAKCGKGLESTTLADKDGEIYCKGCYAKNFGPKGFGFGQGAGALVHSE
What is the function of this protein?
Could play a role in neuronal development.
What are the official names of this protein?
Cysteine and glycine-rich protein 1, Cysteine-rich protein 1, CRP, CRP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUCC_SHEB5
Sequence: MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGHIGGNLWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIEKVAEETPELIHTAIIDPLTGPQGYQARDLGFKLGLNPTQMKQFTKIFMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALYRQPKIKGMHDPSQDDAREAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREVLAKSGLDIIAATSLTDAAEQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: IPGF_SHISO
Sequence: MSRFVFILLCFIPYLGRADCWDKAGERYNIPSSLLKAIAEKESGFNKFAVNVNNNGSKDYGIMQINDFHSKRLREMGYSEEMLISHPCLSVHYAAKLLNEFMMMYGRGWEAVGAYNAGTSPKKKKERLKYAEDIYRRYLRIAAESKQNNRRI
What are the official names of this protein?
Protein IpgF.
What is the protein family that this protein belongs to?
Belongs to the IagB/IpgF/P19 family.
Protein: HEM1_MARN8
Sequence: MALVTLGINHRTAPVEIRERVAFTPERMAEAFSELRAASGASEAAILSTCNRTELYLAGDDDCAPSVLRWLAGFHELDVADLENVLYVHRDSDAVRHMMRVAAGLDSMVLGEPQILGQLKDAYALAREHSATGSFLSRLFEQTFSVAKRVRTQTAIGENPVSVAYASVSMAHHIFADMSRNKALLIGAGKTIELVARHLAEAGVRSFLVANRTLEKAQALAEAHGGKGILLSEIPDHLSDVDIVISSTASPLPILGKGAVERALKKRKHRPYFMVDIAVPRDIEPEVASLADVYLYTVDDLRQVIEENIRSREGAAREAENLISSGVQDFLDQLRALDAVSTLKVFRQRAELLRDVETEKALRALRNGTDPETALRSLARGLTNKLLHQPSVQVRKAMAEGRTEVTECLRELYQLDALEADEPTTTEKL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RL34_SALA4
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SYFB_THEVB
Sequence: MRVSLRWLRELVAVDLDVTMLADRLTMAGFEVEDIEDRRTWAEGVVVGYILACEPHPNAQKLRVCQVDVGQGEPRTIVCGAPNAAAGLYVPVALPGAYLAKIDLKIRPAKLRGVKSEGMICSLAELGLTKESEGIHTFTDAVTVGEDVRPLLGLDDVILHLTSTANRADALSMVGIAREVAALTGAPLTLPTPRAIAPKKSGAKGPVQLAIADPQACPAYCGTLITHVQIAPSPLWLQQRLEAAGLRAINNVVDITNYILLKWGQPLHAFDWDRLQKVAAQTPVSVGVRFAKAGETLKTLDGQERRLSSENLLITAGDVPVALAGVMGGEETEVHPGTQNVFLEAALFASPVIRRSARAQGLRTEASARYERGVNPAELEAATAEAIALLKEIAQGTVSDTTLADQRPPLERTLTLRLEQVHRLLGAVVSEAEDSDEPAYLDPETVEELLSRLGFHLSRQETLEDELVVWSVTVPPYRFRDIEREVDLIEEIARLYGYDRFEETLPAQTEVGALPLELTLLREVRAAFRGAGLTELMHYSWVKGGQPNQVTVVNPLVAEFSSLRTDLITGLVQAFRYNHEQGNPPLNGFEIGRVFGQDEEGLWENDRLGGIIGGDPWQGKWVRRSQQPQPLTWYEAKGILESVFQRFGLNVEYQSDRHDERLHPGRTAVLCLQGERLGIFGQLHPQYAATLEIPAAIYVFELDLEVLLSRLEERYRQIVFQPFSTYPASDRDLAFFAPTALTVAELSRTIWKAAGGRDSFLESVELFDEYSGSGVPAGQRSLAFRLTYRASDRTLTEAEVNELHQRIRDSLVEKYAVTLRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_KORVE
Sequence: MSTYFPKGEVARKWFVVDADGQTLGRLASRVARILSGKDNPKYTPFIDTGDHVVVINAEKIKITGLKADNKKYYHYSGYPGGMKEEEFLKRLERRPELILETAIKGMLPKSKLGKAMGGKLKVYRGADHPHIAQKPEVLANA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: DUX5_HUMAN
Sequence: MPAEVHGSPPASLCPCQSVKFRPGLPEMALLTALDDTLPEEAQGPGRRMILLSTPSQSDALRACFERNLYPGIATKEELAQGIDIPEPRVQIWFQNERSCQLRQHRRQSRPWPGRRDPQKGRRKRTAITGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPIG
What are the official names of this protein?
Double homeobox protein 5.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCE3_ARATH
Sequence: MVLSKTASKSDDSIHSTFASRYVRNSISRFEIPKNSIPKEAAYQIINDELKFDGNPRLNLASFVTTWMEPECDKLMMESINKNNVEMDQYPVTTDLQNRCVNMIARLFNAPLGDGEAAIGVGTVGSSEAVMLAGLAFKRQWQNKRKALGLPYDRPNIVTGANIQVCLEKFARYFEVELKEVKLREGYYVMDPDKAVEMVDENTICVVAILGSTLTGEFEDVKLLNDLLVEKNKKTGWDTPIHVDAASGGFIAPFLYPDLEWDFRLPLVKSINVSGHKYGLVYAGIGWVVWRTKTDLPDELIFHINYLGADQPTFTLNFSKGSSQVIAQYYQLIRLGFEGYRNVMDNCRENMMVLRQGLEKTGRFNIVSKENGVPLVAFSLKDSSRHNEFEVAEMLRRFGWIVPAYTMPADAQHVTVLRVVIREDFSRTLAERLVADFEKVLHELDTLPARVHAKMASGKVNGVKKTPEETQREVTAYWKKFVDTKTDKNGVPLVASITNQ
What is the function of this protein?
Catalyzes the production of GABA.  The calmodulin-binding is calcium-dependent and it is proposed that this may, directly or indirectly, form a calcium regulated control of GABA biosynthesis (By similarity).
What are the official names of this protein?
Glutamate decarboxylase 3, GAD 3.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: MURB_COXB2
Sequence: MDKENFTRLRGELFCDHPLARYTSWRVGGKAERFYRPADLFDLQDFLTQLPSDEPLTWLGLGSNVLIRDGGIKGTVILTLNRLKELSVVNSQLVFREKSGTEDFFSGNGKTIIRAEAGVTCAKLAKFCVSQGLEDGAFFAGIPGTVGGALAMNAGAFGGETWRTVIGVETMNHQGEILKRTPDEFKIHYRQVEGLENQFFIAGYFCFNHGDPDKAKTAINALLKKRNLSQPIGKYSCGSVFRNPPGDYAARLIESAGLKGKSIGNAEVSEKHANFILNKGNASAADIEALIHYVAQHVSQIHGIQLVKEVNIIGRS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRD2_MOUSE
Sequence: MLQNVTPHKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLAPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSITSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVSAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTALPPGLTKSSSESSSEESSSESSSEEEEEEEEDEDEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRIGIDEDDKGPRAPRPPQPKKSKKAGGGGSNATTLSHPGFGTSGGSSNKLPKKSQKTAPPVLPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIRKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKASEKTESSAQQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSDSG
What is the function of this protein?
Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling.  Regulates transcription of the CCND1 gene.  Plays a role in nucleosome assembly (By similarity).  May play a role in spermatogenesis or folliculogenesis.
What are the official names of this protein?
Bromodomain-containing protein 2, Female sterile homeotic-related protein 1, Fsrg-1, Protein RING3.
What are the subcellular locations of this protein?
Nucleus. Note=Detected on chromatin and nucleosomes.
Protein: SMP3_ASHGO
Sequence: MRLAVIRYIWLLVALLVALEPAYVHPDEHMQSVEVMMQKIFGLRGTVPWEFQPEYAARSFAPLWIFMGPALVAARLFNAGPRVVLGLLRIQGYFLYVSLTRVAVELVGRTKLRRSMAAFLLSTTYVVGAFQSHTFSNSIETLLAVAAVGLLEVVIADGRAGHRHVRISGVLGFLIALGLFNRVTFAGYLGLPCIVAFWQFYRRQWRSLAALLLCFLLTSGACIWIDTLSYGTSEWVITPLNNLLYNMDEENLAQHGLHPRYTHILVNLPMLLGPGLLFALGGIQRLSLPLLSCVSGVATLSLFKHQEARFLLPVVPLFLMSVDLTKLRTVSLTLTLKLWLAFNGLMVVIMGVGHQRGVITALHQLREEPIGVQVWWKTYSPPTWVLMNEALTVSTTNFVGDDERIDEVPLDVTRNHVIDLKGCNIELLNHTLSQFIAAGSKVHLIVPDSVAKKTALLTKRYGFDIHREFRTLVHLDLDHLDWSEPSSFTPGLSIYTVT
What is the function of this protein?
Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly.  The presence of a fourth mannose in GPI is essential in fungi (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 4, GPI mannosyltransferase IV, GPI-MT-IV.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CXCR6_MACNE
Sequence: MAEHDYHEDYGLNSFNDSSQEEHQDFLQFRKVFLPCMYLVVFVCGLVGNSLVLVISIFYHKLQSLTDVFLVNLPLADLVFVCTLPFWAYAGIHEWIFGQVMCKTLLGVYTINFYTSMLILTCITVDRFIVVVKATKAYNQQAKRMTWGKVICLLIWVISLLVSLPQIIYGNVFNLDKLICGYHDKEISTVVLATQMTLGFFLPLLAMIVCYSVIIKTLLHAGGFQKHRSLKIIFLVMAVFLLTQTPFNLVKLIRSTHWEYYAMTSFHYTIIVTEAIAYLRACLNPVLYAFVSLKFRKNFWKLVKDIGCLPYLGVSHQWKSSEDNSKTFSASHNVEATSMFQL
What is the function of this protein?
Receptor for the C-X-C chemokine CXCL16.  Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
What are the official names of this protein?
C-X-C chemokine receptor type 6, CXC-R6, CXCR-6, G-protein coupled receptor bonzo.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTNA_PODAN
Sequence: MATLQAIKYSRGKLLVLDQLRLPHENHYDEVSTAEEAFDCIRSMRVRGAPAIAIVAALAHAVELHNGDCTATEPEEVIAHIEKRLDYLKESRPTAVDLSNAITLLKLATRAANLEGLAHPEAKEAILNTYIQTAEEILAKDLHNNTSIGSYGTAWLQQQYSASSEKPISVLTHCNTGSLATSGHGTALGIIRTLHSEGLLKHAYCTETRPYNQGSRLTSFELVFEGIPSTLITDSMAGALFNLHRERMNIGAVIVGADRVVRNGDTANKIGTYQLAVLARHHGVKFVVAAPTTSIDLETGNGSAIEIEERKREELTQISGAIVNEDGTVDTSKTARVAIADQRIGVWNPAFDVTPHELIDAIVTERGTVVKGADGKFDFSQVLPERLASVAARQL
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BIOD_CORK4
Sequence: MSIVIMTGTGTDVGKTVATGAVACVLQKEGYEPFIVKPAQTGEPEGEGDAPRVTALTGIDNAETLYRFPEPLAPATSARRANMPYPELTTVAEEIKSFDKPGRVVLVEGAGGLLVRIGQDWTIADLARELGAPIIVVCSTGLGSLNEAELTVEAATRRGLTVLGLIGGSIPDSPDLATRCNKEDLPVVTGTDVLGYIPEGAGGWSQQRFVQEAPGFFVPDVVGRVTRESD
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_BLOPB
Sequence: MITTNTSSENWDLYRKVTHCLVGHTRLVLSYSGGLDSTVLLDILTRLKNNSDHFTSSPFMLRAIYVHHGISNYSDEWASHCFNQCKIRGIPFSVIHINCYNAENKQRNIEALARNLRYKKLYNRLNSKEILLTAHHMNDQVESLFLALKRGSGPSGLSGMSKNALYANKYRLLRPLLDCSREQLEMYAYKKKLVWIEDDTNTDTRFDRNFLRIKILPSIYQRWPCFNQVVARTAQLCRDQENLLNELLSESFQKLIDESDGSLLFIPLFQYSIPKRQALLRRWLLHFSMKMPSYQLINRIWKEVVLSRKDATPILQLDKYLCRRFREKLYILPVNMRCSLNRIELSWNIIHNVFILPYNLGKLIYQPLSINEHVPKNPFDLHLNINSSLNTSHDVFEKYKKVLTHCFVRSPKSDEKISIIFGNIDGLLYILGRNHGRHLKKIWQELGVPPWLRSRIPLLFYNKTLITAIGVFITHNGKIISKENTLWKISWLQDIISYKIFKNSVRYHLE
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM1_THEON
Sequence: MELKEVREGLARILVPKAERIYDAPVFYNPLMALNRDISVLALKALGSRRVLDALSATGIRGIRYALETPAGEIWLNDINPNAFRLIVDNVKLNFSGELEIEGKMAVLEGEKTLVVTNADANRLMNEQFRYFDFVDLDPFGSPMEFLDSALRAVKRRGVLAITATDTGVLCGAYRNACLRKYLAEPIRGELCHEAGLRILIGTLVRYAAKYDLGVEVLLAYYRDHYFRAFLQLRNGAKTADKSMKQLGYLYQDESGKFEFENTFLPSKATAHGPLWLGPLKNQEFVEELHRLSAEHPLGSKKTQKFLGLLKDELEVPFFYDTHAVARRHGLEVRKLAGVIEILYEKGYKATRTHFSPTALKTDAPFEEVLEALRELQ
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.