PharMolix/UniProtQA huggingface dataset:
Protein: NEC2_BOVIN
Sequence: MRGGCISQGKAAAGLLFCVMVFASAERPVFTNHFLVELHRGGEEKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKARRRRSLQHQQQLERDPRVKRALQQEGFNRKKRGYRDINEIDINVNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWSNSHGTRCAGEVSAAANNNICGVGVAYGSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPTTGKPVLTLTTDACEGKENFVRYLEHVQAVVTVNATRRGDLNINMTSPMGTKSILLSRRPRGDDAKVGFDKWPFMTTHTWGEDARGTWILELGFVGSAPQKGVLMEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKEELEEELDEAVQRSLKSILGKD
What is the function of this protein?
Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues.  Responsible for the release of glucagon from proglucagon in pancreatic A cells (By similarity).
What are the official names of this protein?
Neuroendocrine convertase 2, NEC 2, Prohormone convertase 2, Proprotein convertase 2, PC2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Localized in the secretion granules.
Protein: TBP_ASFM2
Sequence: MEDETELCFRSNKVTRLEMFVCTYGGKISSLACSHMELIKRLQIAEPVKALNCNFGHQCLPGYESLIKTPKKNKNMLRRPRKTEGDGTCFNSAIEASILFKDKMYKLKCFPSTGEIQVPGVIFPDFEDGKNIIQQWVEFLQHQPIEKKVQIIEFKTIMINFKFQINPVSPRVIIHLKKFAALLEQIPTPYPIREIKPPLEDSKVSAKFMVSPGKKVRINVFLKGKINILGCNTKESAETIYTFLKDLISVHWQEILCVLPVPD
What is the function of this protein?
Putative TATA-binding protein.
What are the official names of this protein?
Putative TATA-binding protein pB263R, TBP.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B263R family.
Protein: DF157_ARATH
Sequence: MAKISCSSFFVLMLVFSVFSLVEKAKGDERCTIIIHPGSPCDPSDCVQYCYAEYNGVGKCIASKPGRSANCMCTYNC
What are the official names of this protein?
Putative defensin-like protein 157, Putative low-molecular-weight cysteine-rich protein 22, Protein LCR22.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4UH_SINFN
Sequence: MLKHPTLNLLQQLGLAGMADAFTRLADNDESDNLSHGEWLALLLDQEATWRNNKRLALRLRNAKLHHPAVPEDIIRRAPREYDRTILDLLIAGDWIRKHENCAIVGPTGIGKSWLACALGHKACRDNHSVLYVRMPALLQSLEQARGIGSLATRLKSLGAVELLILDDYGLQPIDGNAPHYLLEILEGRYGRRSTLVTSQFPVARWHEKISDPTYADAILDRLVHNAHRLEMSGESMRRLRQPAEIQT
What are the official names of this protein?
Putative insertion sequence ATP-binding protein y4uH.
What is the protein family that this protein belongs to?
Belongs to the IS21/IS1162 putative ATP-binding protein family.
Protein: NRAM4_ORYSJ
Sequence: MEEGAKIGREHEQQQQQHGRVNGSGRVAAVGGGSGGGGDEIEIEVAAAAGASPSRQHGGLHGDVQAPTWKRFLAHVGPGFVISIAYLDPSNLQTDLVAGSSHRYSLLWVLLFGFIFVLTVQSLAANLGIITGRHLAELCMGEYPKYVKYCLWLLAELGVIAATIPGVLGTALAYNMLLHIPFWAGVLACGACTFLILGLQGYGARKMEFTISVLMLVMATCFFMELGKVNPPAGGVIEGLFIPRPKGDYSTSDAVAMFGSLVVPHNLFLHSSLVLTRKMPYTSKGRKDASTFFLLENALALFIALLVNVAIVSISGTICANNLSFADTSTCSSLTLNSTYVLLKNILGKSSSTVYGVALLVSGQSCMVATSYAGQYIMQGFSGMRKCIIYLVAPCFTLLPSLIICSIGGTLRVHRIINIAAIVLSFVLPFALIPLIKFSSSCTNIGPYKNATSIIRIAWILSLVIIGINIYFFCTSFVAWLVHSDLPRVVNAIISSLVFPFMAAYIAALIYLAFRKVNLSDPFPTNSVSGEIEVQHIQIQEKQEDLGVHL
What is the function of this protein?
Probable metal transporter.
What are the official names of this protein?
Metal transporter Nramp4.
What is the protein family that this protein belongs to?
Belongs to the NRAMP (TC 2.A.55) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NDHH_MARPO
Sequence: MMILTKNKPMIVSMGPHHPSMHGVLRLIVTLDGEDVLDCEPVLGYLHRGMEKIAENRTIVQYLPYVTRWDYLATMFTEAITVNAPEKLTNIQVPKRASYIRIIMLELSRIASHLLWLGPFMADIGAQTPFFYIFREREMIYDLFESATGMRMMHNYFRIGGVAVDLPYGWIDKCLDFCDYFLPKINEYERLITNNPIFLKRVEGIGTVTREEAINWGLSGPMLRASGVQWDLRKVDHYECYDELDWKIQWQKEGDSLARYLVRIGEMKESVKIIQQALKAIPGGPFENLEARRLNQGKNSEWNLFEYQFISKKPSPTFKLPKQEHYVRVEAPKGELGIFLIGDDSVFPWRLKIRSPGFINLQILPQLVKGMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: GUDIS_FUSPR
Sequence: MVKFDSGSESEMTNGDDLHINSKHEVKSRMANGNGVHNVPDHDQFQDRAEMEVLILPDLFSSLMSVPARENPHYASVKADADEWISSVINADAKWASRNKRVDFTYLASIWAPDCSAFALRTSADWNSWAFLFDDQFDEGHLSNDLDGAINEIARTREIMEGTAPRYTADSEHPIRYVFQTLCDRVKQSPEGFYAGKPSSERFYRRWMWAHELYWEGLVAQVRTNVEGRSFTRGPEEYLAMRRGSLGAYPALVNNEWAYGIDLPEEVADHPLVFEIMVIMSDQILLVNDILSYEKDLRLGVDHNMVRLLKAKGLSTQQAINEVGVMINNCYRRYYRALSELPCFGEEADRALLGYLEVEKNHALGSLLWSYKTGRYFKSKEDGARVRKTRELLIPKKMAAL
What is the function of this protein?
Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) to yield the bicyclic sesquiterpene guaia-6,10(14)-diene via a 1,10-cyclization, which requires the abstraction of the pyrophosphate from FPP to yield the (E,E)-germacradienyl cation.  The only accepted substrate is farnesyl diphosphate (FPP).
What are the official names of this protein?
(1R,4R,5S)-(-)-guaia-6,10(14)-diene synthase, Sesquiterpene cyclase, Terpene synthase, Type I terpene cyclase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: MAD4_HUMAN
Sequence: MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDADDHYSLQSGTGGDSGFGPHCRRLGRPALS
What is the function of this protein?
Transcriptional repressor.  Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'.  Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity).
What are the official names of this protein?
Max dimerization protein 4, Max dimerizer 4, Class C basic helix-loop-helix protein 12, bHLHc12, Max-associated protein 4, Max-interacting transcriptional repressor MAD4.
What are the subcellular locations of this protein?
Nucleus.
Protein: FGOP2_CHICK
Sequence: MKMSCTIEKALADAKALVERLREHDNAAEALIEQTTALNKRVEAMKQYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLLMASKKDDPSIIMKLKEQHSKELQVHVDQITEMAAVMRKAIEIDDKHGCKEQERIIQLEQENKGLREILQITRESFLNLKKEDASESTSLSGLVTSSDLSLRKS
What are the official names of this protein?
FGFR1 oncogene partner 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SIKE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_CARHZ
Sequence: MKFYLDEGIVLKGSDFGDGHRMLTIITKELGKIKAVAYGAKKVKSKKRGALLEFSRTNIYLRQSNDYFIVEQAEGIEYFPNLYGNKDLLHAAGQIAWLTDRFWPLGQLNPKLYNWVLYSLRLLNSGVWPKIVLRNFELKLLAFTGFRPITTHCAVCRKPYRGEVWYFGAGEGGIVCPSCRPIEGIYFEIFPEVVKGMNALLLASPEKLPELLLDERVVDRVKTILEYFLGYQLGEPIRLL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: Y834_METJA
Sequence: MFMDYKYFFITIILISIFCGCYEKSYSFVEYNRHYELNEPNNTKNPNYDQNIFLNHDLPKTYPKMYKFPKNYYELSDKMFPDVKKRDLDTLSYILKTIKLPAYKKNYYDCSEASCQLEWILEGYGFKTYLVYGILDTYGNSGSHMWVAVQLDNGKMVLVESTYLCENYYCPDYAIIYKNYNLNNIVIVRDMKYIPKFYADTPDMFLIPHNNRRFLITQLDWWNHPKNAEIKKEMFNLK
What are the official names of this protein?
Uncharacterized protein MJ0834.
Protein: MNMG_LEPIN
Sequence: MIESKNQSFFPNRFDCVVVGAGHAGSEAAYISSKGGARTLLITMNLDTIGQMSCNPAIGGIAKGHMVREVDALGGIMGKMIDNTGIQFKMLNTSKGPSVWAPRAQAEKKEYQLKVKHTLEAEKNLSIRQDTVEELIIENDQVIGVRTGRGFEIFTDHVILTTGTFLSSLVHIGTYQNENGRMCEPTVKGLSKSLAKYNLKLGRLKTGTPPRIHKNSVDLSVLTIQEGDSNPSPFSFSTDKITRKQIPCFITYTNAETHKLIHENLNLSPMYSGQIQSTGPRYCPSIEDKVVRFADRERHQVFLEPEGYETSEIYLNGVSTSLPEEVQWKLVRSLKGLENAEIVRPGYAIEYDYVDPTELKPTLETKKIKGLYHAGQINGTTGYEEAAAQGLVAAYSVLHSLRNLTPLLFKRSESYIGVLIDDLVHKGVEDPYRMFTSRAEHRLLLRQDNADQRLMKYGYDLGLVDQKSYDCMKEKYERVNSVREKIYQIPLKPSDKFQNLLDQKGITNYKFGMKLDSFLKRPEIKIKDIEFMIPEVSSWSDLEKSILEMEIKYEGYIKRELETIQWKNKYLDLAIPEDINYEMIAGLKKEAIQKLKSHKPMTLEKASQISGVDPSDVDLILYHIKGKKKQEVEIF
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37A_ICTPU
Sequence: MAKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRRAVGIWHCGSCMKTVAGGAWTYNTTSAVTVKSAIKRLKEMKDQ
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L37a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_STAS1
Sequence: MTILDEIVDYKRNLIKEGYYEEKLKTLNEVDITHKSSFKSQLDESNQLAVIAEIKSKSPTLDQLPNRDLAQQVKDYEANGANAVSILTDEHYFGGSYERLQDLTLQTTLPVLCKDFVVDKIQIDVAKKAGASIILLIVNVLTDQQMKDLYQYATSLNLEVLVEVHDKEELERAYKLKPQIIGVNNRDLKRFVTDVLHTNEILENKKEGYYYISESGIRDEQDVANVVESGIDGLLIGESLMKCEDLSQFLPGLKLTKVTK
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: CENPU_MOUSE
Sequence: MAARRSLRYSGNPGAKHSKNTLRSTYSRKQKAGPKPRPKDVFDFSNNSDASSIPGALEEEEETYETFDPPLHSTAIYAEDELSKHCVSSSSLATHRGKASRNLDPSEDEASGNESIKVSTKKPRRKLEPISGESDSSADDVRRRVASAEGPRSQQRQAAPAAPSPPERPAEPVTPRRTRLHSAQLSPVDETPATQSQLKTQKKVRPSPGRRKRPRRGHTDTDGSESMHIWCLEGKRQSDITELDVILSVFEKTFLEYKQRVESESCNQAINKFYFKMKGELIRMLKEAQMLKALKMKNTKIIANMEKKRQRLIEVQDELIRLEPQLKQLQTKYDDLKERKSSLKKSKHFLSNLKQLCQDYSNVQEKGPKGTGKYDSSSLPALLFKARSILGAENHLRTINYQLGKLLELD
What is the function of this protein?
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.  Plays an important role in the correct PLK1 localization to the mitotic kinetochores.  A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation.  Involved in transcriptional repression (By similarity).
What are the official names of this protein?
Centromere protein U, CENP-U, MLF1-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the CENP-U/AME1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Note=Localizes in the kinetochore domain of centromeres. Colocalizes with PLK1 at the interzone between the inner and the outer kinetochore plates (By similarity).
Protein: COQ8B_HUMAN
Sequence: MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSWVDPS
What is the function of this protein?
Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:24270420).  Its substrate specificity is unclear: does not show any protein kinase activity.  Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway.  Required for podocyte migration (PubMed:24270420).
What are the official names of this protein?
Atypical kinase COQ8B, mitochondrial, AarF domain-containing protein kinase 4, Coenzyme Q protein 8B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein. Cytoplasm, cytosol. Cell membrane.
Protein: TRM5_ASPFU
Sequence: MDSMTDSSNSLRSSDLPEMFRPPVNRAMRVLDRSFFRKTVPLSAAAVFQNSDISKVRAELHKSRDLLAVPRLNCIRDVADQEGQIKKALLLRETVKHDDKETWSPKISELVEKGRIAMRPYDLTLDYDFWTYADIISSILPEDELQEIPQGFTQVGHVLHLNLREQYLPYKYLIAEILKDKNKVIRTVINKTEDVGSHSEFRTFPFELLAGDNDLNVVQHEQDCEFRFDYSRVYWNSRLETEHRRLVEKFNKGEMVCDVMAGVGPFAVPAGKKKIFVWANDLNPHGYEVMQDAIKRNKVEGFVTPFNMDGREFIRWSAKELLETEPVTVTIHPKVRRDRKSGNKVEQAPPPHPEEYHRPVFFDHYVMNLPATAIEFLDAFPGIYAGKESLFAPHTSQRLPMVHVYCFSGHSENELDDHIDICQRISERIGYTITPEDRIGGSGNQSVELSIHNVRLVSPKKQMFCASFRLPAEVAFKKV
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: BOP1_DROSE
Sequence: MTKKLALKRRGKDSEPTNEVVASSEASENEEEEEDLLQAVKDPGEDSTDDEGIDQEYHSDSSEELQFESDEEGNYLGRKQSSSAEEDEESSDEEDNEEEGSTDEEEVEDEEKVSKSKQSDDKPSGSGAASKKALTAELPKRDSSKPEYQDSDTSDEEDIRNTVGNIPMHWYDEYKHIGYDWDAKKIIKPPQGDQIDEFLRKIEDPDFWRTVKDPLTGQDVRLTDEDIALIKRIVSGRIPNKDHEEYEPWIEWFTSEVEKMPIKNVPDHKRSFLPSVSEKKRVSRMVHALKMGWMKTTEEVEREKQAKRGPKFYMLWETDTSREHMRRIHDPVSAPKRDLPGHAESYNPPPEYLFDAKETKEWLKLKDEPHKRKLHFMPQKFKSLREVPAYSRYLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPRDLQPFPTVESMVYRGHTDLVRSVSVEPKGEYLVSGSDDKTVKIWEIATGRCIRTIETDEVVRCVAWCPNPKLSIIAVATGNRLLLVNPKVGDKVLVQKTDDLLAEAPSQDVIESERIKTAVQWSNAEADEQEKGVRVVITHFKPIRQVTWHGRGDYLATVMPEGANRSALIHQLSKRRSQIPFSKSKGLIQFVLFHPVKPCFFVATQHNIRIYDLVKQELVKKLLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDLSTKPYQTMRLHRNAVRSVAFHRRYPLFASGSDDQAVIVSHGMVYNDLLQNPLIVPLKKLQTHEKRDEFGVLDVNWHPVQPWVFSTGADSTIRLYT
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: SPRE_BOVIN
Sequence: MEGSVGKVGGLGRTLCVLTGASRGFGRTLAQVLAPLMSPRSVLVLSARNDEALRQLETELGAEWPGLRIVRVPADLGAETGLQQLVGALCDLPRPEGLQRVLLINNAGTLGDVSKRWVDLTDPTEVNNYWTLNLTSTLCLTSSILQAFPDSPGLSRTVVNISSICALQPFKGWGLYCAGKAARNMMFQVLAAEEPSVRVLSYGPGPLDTDMQQLARETSVDPDLRKSLQELKRKGELVDCKISAQKLLSLLQNDKFESGAHIDFYDE
What is the function of this protein?
Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
What are the official names of this protein?
Sepiapterin reductase, SPR.
What is the protein family that this protein belongs to?
Belongs to the sepiapterin reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_LACCB
Sequence: MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVVIGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHDLLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDIFTNHNVIVESF
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PELO_METM6
Sequence: MKIIQEIPERNIIKLIPENLDDLWHLSNIIQPYNAIYAVTERRTEDKGDKLRADRGTKRRVFLGIKAEKINFHEDFNRLRVSGKIIHAPDDIPIGSYHTIDIEPLLQVSVQKNWKKWDLARLKDAEDSSKKPKVVVVIMDDSEADIFLVREFGIKELASIKSGISKKLDYKQNEQAKFSYYSDIINSISEYEGKILFAGPGFGKNNIQNYISEKHKDLAPNVVIESANHTGKSGLSEILKSGIIDKIYGEARISKETQIIEKLLEEISKKGLAAYGIESVSNAMNYSAIDTLLLTDEYLRRNRRTIEELMNNVENINGNILIISTEHDAGKQLKALGGISALLRFPIE
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_CLOPS
Sequence: MWKEFKEFAMKGNVIDLAIGVIIGGAFGKIVTSLVNDIIMPVIGRLVGKVDFSNLYINLSGQQFNSLQEAQAAGAATINYGLFLNNLINFLIIAFSIFIVIKQINKLKNFTKKKEEVQVEATEKDCPYCCTKIDIKATRCPHCTSVLEEATNQSS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL34_BORAP
Sequence: MKRTYQPSRVKRNRKFGFRARMKTKGGRLILSRRRAKGRIKLTVSDEKKKY
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PKS24_DICDI
Sequence: MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII
What is the function of this protein?
Probable polyketide synthase.
What are the official names of this protein?
Probable polyketide synthase 24, dipks24.
Protein: RIBB_ECO24
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: PYRG_FLAJ1
Sequence: MNQTKYIFVTGGVTSSLGKGIIAASLAKLLQGRGYRTTIQKFDPYINVDPGTLNPYEHGECYVTDDGAETDLDLGHYERFLNVPTSQANNVTTGRVYLSVIEKERRGEFLGKTVQVVPHITNEIKDRMQLLGKSGDYDIVITEIGGTVGDIESLPYIESVRQLVWELGENNGIVIHLTLVPYLAAAGELKTKPTQHSVKTLMESGIKADILVCRTEHELSQELRQKLALFCNVKKEAVIQSIDASTIYEVPNLMLEEGLDVVALKKLDLPKKASPDLKNWNTFLKRLKSPKQTVNIGLVGKYVEMQDCYKSILEAFIHAGAANETKVNVISIHSEHINADNVEEKLGTLDGVLVAPGFGERGIEGKIEAVRYVRENNIPFFGICLGMQMSVIEYSRNILGYADANSTEMNEKTPHPVVNLMEEQKNITDKGGTMRLGAWKCDIKPNTLAHRIYGEKTISERHRHRYEYNNKYADELQKAGLKASGVNPDTGLVEIVELENHPFFIGVQYHPEYKSTVANPHPIFVNFVAAAVNAHKK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: HOA_ECO7I
Sequence: MNDKKLYISDVTLRDGMHAIRHQYSLENVRQVAKALDDARVDSIEVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQAGARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGATCIYVVDSGGAMNMSDIRDRFRALKAVLKPETQTGIHAHHNLSLGVANSIAAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLRNNK
What is the function of this protein?
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde.  Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.