PharMolix/UniProtQA huggingface dataset:
Protein: RL3_BURM7
Sequence: MSLGLVGRKVGMTRIFTAEGDSIPVTVLDVSDNRVTQIKTVETDGYTAVQVAFGSRRASRVTKPLAGHLAKAGVEAGEILKEFRIEADKAAELSNGAVIGPDLFEVGQKVDVQGVSIGKGYAGTIKRYNFGSGRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHMGDETVTVQNLEIARIDADRKLLLVKGAVPGAKGGKVFVTPAVKTRAVKGAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: P2C28_ARATH
Sequence: MKKTIKNSTHRPEDILVHAIKKRRSASGDVKNAVKLKEGEDYLRVEEEIPHDDNVVVIDDGCDHDHDVDDNDDDEEENGRYCRREFDHGYHLVKGQMGHGMEDFIVADTKTVKGHNLGLYAIFDGHSGSDVADYLQNHLFDNILSQPDFWRNPKKAIKRAYKSTDDYILQNVVGPRGGSTAVTAIVIDGKKIVVANVGDSRAILCRESDVVKQITVDHEPDKERDLVKSKGGFVSQKPGNVPRVDGQLAMTRAFGDGGLKEHISVIPNIEIAEIHDDTKFLILASDGLWKVMSNDEVWDQIKKRGNAEEAAKMLIDKALARGSKDDISCVVVSFLQWID
What are the official names of this protein?
Probable protein phosphatase 2C 28, AtPP2C28.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: AMPP3_FUSV7
Sequence: MFAEDLDRILSGKYPGKSHALRVVELLREKVPNAKGYLYLEGRMSKLLEDSDEFEPFRQRRHFYYLTGCDLSNCYLLYDIDSSKSTLFIPPIDPEEVVWSGLPLSPQQGLEKYDVDEVKFSTELDNILSHLSGSQESTVYTIADQVCPHIKFGLDNVDSSILKGVIDRCRVVKDKYEVAMIRKANNISSLGHEAITKQASKASNEMQLEATFLGHCVAHGAKKMAYPPIVAAGRSGAILHYEANDQPLGGKQNLLVDAGAEWNNYASDITRTFPLSGTFTKESRQIYDIVYKMQMECIAIIKAGVRWEDVHMLAHEIAVEGLLQLGIFQGAKADILKAQTSLAFFPHGLGHYLGLDTHDVGGNPNFDDENKYLRYLRTRGTLPAGSVVTVEPGIYFCEHIIRPYLQDERHKDLINSDVLDKYWDVGGIRLTQGSIEDNVLVTPTGVDNLTTTIKHPDQLEGMIRGLEGV
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase PEPP, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: MRAZ_DELAS
Sequence: MFQGASSLNLDGKGRLSVPTRHRDALVAMAQGQVTLTKHPHGCLMLFPRTEWLQFRERIAQLPMSAQWWKRIFLGNAMDVDMDATGRVLVSPELREAVGLTKEVVLLGMGNHFELWDKATYEAHEAKAMQEEMPAAFQDFAF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SSI15_STRBI
Sequence: SLYAPSAVVLSIGKGDASGPVTVLRATTLSCAPVPGGTHPAPEAACAELKAGFAGGGFGGLLASPDPDRACPQHFDPVTVTLDGVWEGARTSWQHTFSNACVMGTTLDGGEAF
What is the function of this protein?
Inhibitor of subtilisin BPN'.
What are the official names of this protein?
Subtilisin inhibitor-like protein 15, SIL-15, SIL15.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I16 (SSI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PBAN_HELAU
Sequence: MFNQTQFFVLLAVFTTSSVLGNNNDVKDGAASGAHSDRLGLWFGPRLGKRSLRISTEDNRQAFFKLLEAADALKYYYDQLPYEMQADEPETRVTKKVIFTPKLGRSLAYDDKSFENVEFTPRLGRRLSDDMPATPADQEMYRQDPEQIDSRTKYFSPRLGRTMNFSPRLGRELSYDMMPNKIRVVRSANKTRST
What is the function of this protein?
A hormone that controls sex pheromone production in females and pheromone responsiveness in male.  Also mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
PBAN-type neuropeptides, Pheromone/pyrokinin biosynthesis-activating neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUSB_BURCM
Sequence: MKKSARRQSRELATQGLYQWLLSNAAPGEIDAQLRGALGYDKADKELLDAILHGVIREHATLIEALTPSLDRPVDQLSPVERAVLLIATFELTHHVETPYRVIINEAVELAKTFGGSDGYKYVNGVLDKLAAKLRPAETQARRNG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CY24B_BISBI
Sequence: MGNWVVNEGISIFVILVWLGMNVFLFVWYYRVYDIPDKFFYTRKLLGSALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRIRRQLDRNLTFHKMVAWMIALHTAIHTIAHLFNVEWCVNARVNNSDPYSIALSDIGDKPNETYLNFVRQRIKNPEGGLYVAVTLLAGITGVVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAQRIVRGQTAESLLKHQPRNCYQNISQWGKIKDCPIPEFSGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVVITKVVTHPFKTIELQMKKKGFKMEVGQYIFVKCPVVSKLEWHPFTLTSAPEEDFFSIHIRIVGDWTEGLFKACGCDKQEFQDAWKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASILKSVWYKYCNKAPNLRLKKIYFYWLCRDTHAFEWFADLLQLLETQMQEKNNTDFLSYNICLTGWDESQASHFAMHHDEEKDVITGLKQKTLYGRPNWDNEFKTIGSQHPNTRIGVFLCGPEALADTLNKQCISNSDSGPRGVHFIFNKENF
What is the function of this protein?
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.  It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior.  Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes.
What are the official names of this protein?
Cytochrome b-245 heavy chain, CGD91-phox, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Heme-binding membrane glycoprotein gp91phox, Neutrophil cytochrome b 91 kDa polypeptide, gp91-1, gp91-phox, p22 phagocyte B-cytochrome.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=As unassembled monomer may localize to the endoplasmic reticulum.
Protein: AROD_METJA
Sequence: MICLPVVEDSVEKAIKTAEKYLEIADIVEFRIDMLKEVSEEDIEKFAKYPCIITVRADWEGGYWKGNNEERLNLIKKAIECNAKFVDIELREEKNKELVKFRDEIGSKTKIIISYHDFEKTPSKEKLVEIVEKALSIGDIAKFATMANSKEDVLNILEVINKYPGKIIGIGMGEKGKLTRILGVYFGSILTFASYKGKSSAPGQVDIDTLKEIWRLMDLK
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: S27A2_MOUSE
Sequence: MLPVLYTGLAGLLLLPLLLTCCCPYLLQDVRYFLRLANMARRVRSYRQRRPVRTILRAFLEQARKTPHKPFLLFRDETLTYAQVDRRSNQVARALHDQLGLRQGDCVALFMGNEPAYVWIWLGLLKLGCPMACLNYNIRAKSLLHCFQCCGAKVLLASPDLQEAVEEVLPTLKKDAVSVFYVSRTSNTNGVDTILDKVDGVSAEPTPESWRSEVTFTTPAVYIYTSGTTGLPKAATINHHRLWYGTGLAMSSGITAQDVIYTTMPLYHSAALMIGLHGCIVVGATLALRSKFSASQFWDDCRKYNVTVIQYIGELLRYLCNTPQKPNDRDHKVKKALGNGLRGDVWREFIKRFGDIHVYEFYASTEGNIGFVNYPRKIGAVGRANYLQRKVARYELIKYDVEKDEPVRDANGYCIKVPKGEVGLLVCKITQLTPFIGYAGGKTQTEKKKLRDVFKKGDIYFNSGDLLMIDRENFVYFHDRVGDTFRWKGENVATTEVADIVGLVDFVEEVNVYGVPVPGHEGRIGMASLKIKENYEFNGKKLFQHIAEYLPSYARPRFLRIQDTIEITGTFKHRKVTLMEEGFNPTVIKDTLYFMDDAEKTFVPMTENIYNAIIDKTLKL
What is the function of this protein?
Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport across cell membranes, playing an important role in hepatic fatty acid uptake (PubMed:9671728, PubMed:15699031, PubMed:20530735).  Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (PubMed:15699031, PubMed:20530735).  Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis (PubMed:15699031, PubMed:20530735).  Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid (By similarity).  May contribute to the synthesis of sphingosine-1-phosphate (By similarity).  Does not activate C24 bile acids, cholate and chenodeoxycholate (By similarity).  In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.  However, it is not critical for THCA activation and bile synthesis in vivo (By similarity).
What are the official names of this protein?
Long-chain fatty acid transport protein 2, Arachidonate--CoA ligase, Fatty acid transport protein 2, FATP-2, Fatty-acid-coenzyme A ligase, very long-chain 1, Long-chain-fatty-acid--CoA ligase, Phytanate--CoA ligase, Solute carrier family 27 member 2, Slc27a2, THCA-CoA ligase, Very long-chain acyl-CoA synthetase, VLACS, VLCS, Very long-chain-fatty-acid-CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Peripheral membrane protein. Cell membrane; Multi-pass membrane protein. Microsome.
Protein: SYGA_HERAR
Sequence: MLTFQQIILTLQKYWDAQGCALLQPYDMEVGAGTSHTATFLRSIGPEPWKAAYVQPSRRPKDGRYGENPNRLQHYYQFQVVLKPAPANILELYLGSLEALGFDLKANDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGINCKPITGEITYGLERLAMYLQGVDNVYDLKWTEGLSYGDVYKQNEIEQSTYNFEHSDADFLFTAFGAHEKQALNLIENKLALPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRNLARSVARSYLDSRARLGFPMATPEHAAEVLAQIEKETA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMAD5_MOUSE
Sequence: MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNAPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMAPDNSQPMDTSSNMIPQTMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
What is the function of this protein?
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.  SMAD5 is a receptor-regulated SMAD (R-SMAD) (By similarity).  Required for angiogenesis.
What are the official names of this protein?
Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, Dwarfin-C, Dwf-C, SMAD family member 5, SMAD 5, Smad5, mSmad5.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4 (By similarity).
Protein: MIAB_BACMK
Sequence: MNEQQRLASRQANSSTKKEEKDYSKYFESVYQPPSLKLAKKRGKEEVKIERDFGLPEEFRDFGAGRKFYIRTYGCQMNEHDTEVMAGIFTTLGYEPTFSTEEADVILLNTCAIRENAENKVFGELGHLKSLKRRNPDLIIGVCGCMSQEESVVNKIMQKNQHVDMVFGTHNIHRLPYILKDAMFSKETVVEVWSKEGDVIENLPKVRRGDIKAWVNIMYGCDKFCTYCIVPYTRGKERSRRPEDIIKEIRHLAANGYKEITLLGQNVNAYGKDFEDIQYGLGDLMDELRKIDIARIRFTTSHPRDFDDHLIDVLGKGGNLVEHIHLPVQSGSTDMLKIMARKYSREHYLELVRKIKETIPNAVLTTDIIVGFPNETDEQFEETMSLYREVGFDTAFTFIYSPREGTPAAKMQDNVPMEVKKERLQRLNTLVNEYGVNKNKRYIGQIVEVLVEGESKNNPEVLAGYTRTNKLVNFVASKSLIGQLVKVKITEAKTWSLNGELVKEPIEVK
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDX1_HUMAN
Sequence: MYVGYVLDKDSPVYPGPARPASLGLGPQAYGPPAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQRPTPYEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQPPQPPMAHDITATPAGPSLGGLCPSNTSLLATSSPMPVKEEFLP
What is the function of this protein?
Plays a role in transcriptional regulation (PubMed:24623306).  Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306).  Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306).  Could play a role in the terminal differentiation of the intestine.  Binds preferentially to methylated DNA (PubMed:28473536).
What are the official names of this protein?
Homeobox protein CDX-1, Caudal-type homeobox protein 1.
What is the protein family that this protein belongs to?
Belongs to the Caudal homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XYL2_ASPFU
Sequence: MSKSTATAQNLSFVLEGIHQVKFEDRPIPELKDPHDVLVNVKFTGICGSDVHYWEHGSIGQFVVKGPMVLGHESSGVISKVGSAVTGLKVGDRVAMEPGIPCRRCEPCKAGKYNLCEKMAFAATPPYDGTLAKFYVLPEDFCYKLPDNISLQEGALMEPLGVAVHIVKQASVTPGQSVIVFGAGPVGLLCCAVAKAFGAAKIIAVDIQKARLDFAKKYAATSTFEPAKVSAVDNADRLRKENNLGVGADVVIDASGAEPSVHTGIHVLRPGGTYVQGGMGRSEIMFPIMAACTKELAIKGSFRYGSGDYNLAVGLVASGKVNVKDLITGVVEFHDAEQAFKEVKAGKGIKTLIAGIQD
What is the function of this protein?
Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
Probable D-xylulose reductase A, Xylitol dehydrogenase A.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: IDI2_METAC
Sequence: MINTTSRRKIEHLKLCAESPVEARGVSAGFEDVTLIHRALPELNMDELDLTVDFLGKRMQAPFLIASITGGHPDTLPVNAALAAAAEELGVGIGVGSQRAAIDDPAQEDSFRVVRDKAPNAFVYGNVGAAQIRQYGVEGVEKLIEMIDADALAIHLNFLQEAIQPEGDRDATGCLDMIAEICSMVRIPVIAKETGAGISREDALLLHKAGVSAIDVGGVGGTSWAGVEVYRAKESKDPVSERLGELFWDFGIPTVASLIESRVSLPLIATGGVRTGLDIAKSIALGASAASAALPFVGPSLEGKESVVKVLSCMLDEFRAAMFLCGCANIQALHNSPVVVTGWTLKYLEQRGFNVKDYSLPKNAL
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOH_XANAC
Sequence: MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSRDDSTPLALPYVVAEIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLAMIAATPRFVRGSDWPSAVQREVFVQFGVELSRDYRGTLERFLALDTLGSAHARSELRSLRETLTARGEPAPEALQQGLTLLERTDLRRTVPQLARPSLWIAGQRDRLVPAAGMHAAAALSPHAQALTIAGGGHAPFLGHADQVSEALQRFVASVP
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNO0_YEAST
Sequence: MLEAKMVMVVPTIEDQAMIVLHPKILSQSVVMHIKGQNYQLDLVKVKHIMIEVGHLDPQVRTGAMVLIKGITAYVKSIRKTVHNVHNYGFLKSHFKRAKTAAKPTLTKLHLTSATRLQKMKKSRIKDSRRMKQLETNFKRKIIEIHEIAVLPIEPMKIKGTTEIERAILRRFRKVPRVGITSVGTRGNY
What are the official names of this protein?
Uncharacterized protein YNL140C.
Protein: YDEA_BACSU
Sequence: MKKALFLILDQYADWEGVYLASALNQREDWSVHTVSLDPIVSSIGGFKTSVDYIIGLEPANFNLLVMIGGDSWSNDNKKLLHFVKTAFQKNIPIAAICGAVDFLAKNGLLNNHSHTGNFVYLWKDYKQYKPISSFVEKQAVRDKNLVTANGTAPIEFTNLILEMIDFDTPENIEKMMYMNRYGFYHFCDKYGNPFVD
What are the official names of this protein?
Uncharacterized protease YdeA.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: RSMH_SOLUE
Sequence: MHVPVMPAEAIELLAIRPEGVYLDATAGLGGHSGLIARQLTTGTVIANDRDTRSLEMARANTAEWSDRMCFHYGSFGSLSDAVSQAGFEKVDGLLADLGVSRYQLTAPDRGFSFMADGPLDMRMDASIQTTAADLVNHTDEKTLADLIYQMGEERRARRIARAIVRARPLRSTLHLADVVERAVPRTGRLHPATKTFMALRMAVNDEPGELRRLLEIAPGLLKSGGRMVVISFMSSDDRMVKEKFKELGQSKQATILTKHPLQPSDEESFNNPASRSAKLRALEMR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CREA_COCCA
Sequence: MQSNSASTGFANLLNPETASQNQQQQQQQPTSTPTASMAAATVSLMAPLLQNAPQQTEEPRQDLPRPYKCPLCDKAFHRLEHQTRHIRTHTGEKPHACTFPGCTKRFSRSDELTRHSRIHNNPNSRRGKGQQHAAATQAAVAAVQAGLMEPGSNLAHMMPPPSKPISRSAPGSQLGSPNVSPPHSFSNYSPGMSNDLAAYHQGGLSNSSSPSGLARPMDLLADAASRLEQRPGHISHSSRHHLTSGYHPYANRLPGLSQYAYSSQPMSRSHSHEDDDPYSHRMTKKSRPGSPSSTAPPSPTFSHDSCSPTPDHTPLATPAHSPRLRPHGFSDLQLPHLRHLSLNQNFVPALAPMEPSTEREQPYVPSQSSGLRIGDIISKPEGAQRKLPVPQVPKVAVQDLLNGPSNSGFSSGNNSATASLAGEDLSNRN
What is the function of this protein?
Involved in carbon catabolite repression.  Represses the transcription of a number of genes by binding to a GC-rich region in their promoter (By similarity).
What are the official names of this protein?
DNA-binding protein creA, Carbon catabolite repressor.
What is the protein family that this protein belongs to?
Belongs to the creA/MIG C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: G3P_THEMA
Sequence: MARVAINGFGRIGRLVYRIIYERKNPDIEVVAINDLTDTKTLAHLLKYDSVHKKFPGKVEYTENSLIVDGKEIKVFAEPDPSKLPWKDLGVDFVIESTGVFRNREKAELHLQAGAKKVIITAPAKGEDITVVIGCNEDQLKPEHTIISCASCTTNSIAPIVKVLHEKFGIVSGMLTTVHSYTNDQRVLDLPHKDLRRARAAAVNIIPTTTGAAKAVALVVPEVKGKLDGMAIRVPTPDGSITDLTVLVEKETTVEEVNAVMKEATEGRLKGIIGYNDEPIVSSDIIGTTFSGIFDATITNVIGGKLVKVASWYDNEYGYSNRVVDTLELLLKM
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD (PubMed:2271518).  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_PHYAS
Sequence: MAKKVVKMVKLQIPAGKANPAPPVGPALGQAQVNIPSFCSQFNETTKDQMGFIIPVIISVYEDRTFTFVTKTPPASDLLKKAAKIDAGSANAKQTKVATISKSQLQEIANLKLRDLNAYSVEQACKIIAGTARNMGILIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NDHK_PROM0
Sequence: MNPQLSPKAIREIREGTCNPLGAPQVTTDLSENIILTSLDDLHNWARLSSLWPLLYGTACCFIEFAALIGSRFDFDRFGLVPRSSPRQADLLIVAGTVTMKMAPALVRLYEQMPEPKYVIAMGACTITGGMFSADSTTAVRGVDKLIPVDLYLPGCPPRPEAIFDAVIKLRKKVGNESILERTKTEQTHRYITSDHEMNLVFSENTGEYLNKTSANSIPSSKKEKITELPDNNEKAEIIDTLEN
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, NAD(P)H dehydrogenase I subunit K, NDH-1 subunit K, NDH-K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PNP_CELJU
Sequence: MNPIIKKFQYGNQTVTLETGRIARQATGAVLVSIGEVAVLCTVVGAKEASPGQDFFPLSVHYQEKAYAAGRIPGGYFKREGRPSEKETLTSRLIDRPIRPLFPEGFLNEVQVICTVVSTDKKQDPDIAAMIGTSAALAVSGIPFNGPIGAARVGYTQGEGYILNPSYKQLETSELDMVVAGTKDAVLMVESEAKELPEDIMLGAVLYGHQEMQAVIQACAELARDAGKARWDWQPVPENTELKTAIKAAFGVAIGDAYRITDKAERYNRLGELRSEAVAQFATEESGISADAVKSLFGTLEYNIVRSRIVANEPRIDGRDNKTVRPITVDVGVLPKAHGSALFTRGETQALVVATLGNARDVQIIDQLEGEKKEAFLLHYNFPPYSVGECGRMGSTGRREIGHGRLAKRGVQAVLPKAESFPYTLRVVSEITESNGSSSMASVCGSSLALMDAGVPLKAPVAGIAMGLVKEDNGFAVLTDILGDEDHLGDMDFKVAGTTSGVTALQMDIKIEGITEEIMEIALEQALAARLHILGEMNKVLSQSRTAVSENAPRFETIKIHPDKIRDIIGKGGATIRSITEETNSSIDIDDDGTVKVYADDNEALQAALNRIGAIVAEAEIGAIYEGTVVRIVDFGAFVNFLPGKDGLVHISQIADERVNNVSDYLKEGQVVKVKCLDVDQRGRIKLSIKEALAEEAGTAPAAEPVADAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_NEIMA
Sequence: MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINPDKRSTYTVAERQDMLCDITKMFPNVRTDVFENRFLVHYAREVDAGFIVRGIRSASDYEYERSMRHINSDLAPEISTVFLMPPREIAEVSSTMVKGLVGPEGWTETIHRYVPQAVYEKILAEHQHEN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_MYCPN
Sequence: MAKTIKHPRWGRYVAEAVGRGHPDKICDQIADSILDECIKQSPTSHVACEVFASKNLIMVGGEILTTGYVDVVQTGWKVLNRLGYTENDFSFLSCINSQSSEINQAVQSNDEIGAGDQGITVGYACSETEQLMPLGSIVAQALVQRAARIIDQYPFIKHDMKSQVVLNYTGNKVQCESVLMSVQHTQDVSLDQLRQTIINQVILPVLTEYGLNDPKIKHLVNPGGSFVVGGPMADTGLTGRKIIVDTYGPYANHGGGSFSGKDPTKVDRTGAYFARFIAKHIVSLGWAEECEVSISWVFSQPLPQSIQVKCFNINKEFSEQLINQVISQYFNWSVAKIIAKLKLLDQVEYFRYAVYGHFGHQTAPWEQLSERDSLQCLIKNFQ
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.