PharMolix/UniProtQA huggingface dataset:
Protein: CRTF_CERS4
Sequence: MSALRPPARGGLGLSRLGVRLAGSRRFQLIAERVPFLRRIGRREGEELFDIVAGFVHSQVLYALVELRVLHLVAEGPQTVQALAAATGLAPERMQLLLQGGAALKLLTRRRDGQFDLAVRGAAFLAVPGLEAMVGHHHVLYRDLADPVAFLKGETEPELARFWPYVFGAGGATDPEVTAKYSRLMTESQGLVAEDALRLVDLMGVRRLMDVGGGTGAFLAAVGRAYPLMELMLFDLPVVAEAAPQRLTEAGLAGRFTVHGGSFRDDPLPLGADAISLVRVLFDHSDETVKLLLHRVREALPAGGRVIVAEAMSGGARPHRETDTYMAFYTAAMRTGRVRSAAEIAELLTGQGFSEIKIFPGLRPYVASAVTAVRPSDAP
What is the function of this protein?
Methyltransferase that mediates the O-methylation of 1-hydroxy carotenoids.  Converts hydroxyneurosporene to methoxyneurosporene or demethylspheroidene to spheroidene.  Also able to produce spirilloxanthin (By similarity).
What are the official names of this protein?
Demethylspheroidene O-methyltransferase, Hydroxyneurosporene methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: GLGA_ACTP2
Sequence: MKILHICSEMYPLIKTGGLADVMGALPYAQQQSGNDVRVLIPLYPQVAEKIGETNEVATIGTFAGLVTIRFTYFNGLGVYVIDAPHLFQRSGNPYHDSGYADYPDNYKRFALLGYLGAQLSEGLDQWWGKADILHAHDWQGGLACAYLKSWNSPVKSVFTIHNIAYPGRFHSYHLHELGLPWHFFQAEGLEFYGEISYLKAGLYFADKITTVSPTYALEITEEIAGGGMHGLLQTRKAQGRLHGVLNGVDDTVWNPETDTNIVATYKPSYMQGKSKNKAELQQMFHLPEDKDAMLMVMVTRLTEQKGADFILDRIDELMEERVQLVVLGSGSPHLEYLLNEARSRHPEQIGIYIGYNEALSHQIIAGGDVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVVDSNKESIEQRTATGFVFNYPSSDDFLEAFRRAVNLWKKNKLWSSVRQNALAQDFGWARAAASYQAIYQEIV
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: AROE_SULIA
Sequence: MLEEINYDTKLFGLIGKNIKYTLSPYIHNFSFTTLGINAVYLVFDLDEMKFNRIINGLLEIAEGLNVTIPYKEEVMKYLDNTDTYSTRIQAVNTIYKKSGYNTDYLAIKNLVRKKIGNMSGYECYVYGAGGAAKAAAFALSELGCSSISIVNRTNLRANELVELLNKNGYNASIKENCNSTSNIVVVNSTPNPSVVPENCIQKSELVIEFVYKPVETELIKNAKKYGIKYIDGLEILVNQAVEAEKIWFNKSVSDEKIIEYLYARKLVW
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: YQGF_EHRRW
Sequence: MLYKNINEFEQVIDKTKRIMCLDFGEKKIGVALSDKTNLIAIPHSVYVRKNTRKDLGSLYGILIENDAGSMVIGLPLDLFGMGNELCDKVMLFANRMIKKYAINIYLHDERYSTAMATRVAKLANIKRKESQKIDDKIAAVLILQQVLDMVKIYQM
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_MARSD
Sequence: MKVLVINAGSSSIKYQLLDMSTGNDLASGIVERIGEEMGSISYKTGEKYTAEQPFPTHREGMVEVINLLTDADKGVVKDKAEIAAIGHRIVHGGELFFEPVEIDDKVLQGIRDCIPLAPLHNPGHVIGIETAMELFPGVRQVAVFDTSFHQTMEPKAYMYGVPYKYYEDWGLRRYGAHGTSHKYVARETAKLLGKPLEESNIITVHLGNGASISAVKNGKCYDTSMGLTPLGGIIMGTRCGDIDPAIVGFIAERTKQSAAEVVATLTNESGLKGICGSNDLRDIHARIEEGDEKAKLALDMACHKVRQFIGAYAFELGRVDAIVFTAGIGENDEIYRENCLSGLENFGITINKEKNENWDRTPSFISEDDGAVKVAIIATNEELEIANDTVKVLGL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS2_GEOSL
Sequence: MEHLYIVSYDIRNQRRWRRLFKTMHGFGCWLQLSVFQCRLDRIRIIKMEAAINEIVNHAEDHVLILDLGPAENVKPKVSSIGKTFDPILRQAVIV
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: RS20_GEOUR
Sequence: MANHKSALKRIKQTEKRTERNRHVRSTLRTFIKRVREAAAAKDAALAKEALAAAIPVIDTAASKGVIHSSNASRNISRLTKLVNTLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HOA1_NOVAD
Sequence: MTSNFNVEAGDKLYIQDVTLRDGMHAVRHMYGIDHVRSIASALDKAGVDAIEVAHGDGLSGASFNYGFGAHTDWEWLEAVADVLEKSVLTTLILPGVGTVEELRRAYDIGVRSVRVATHCTEADVSKQHIGIARDLGMDVSGFLMMSHMIEPEALAQQASLMESYGAQCVYVTDSGGALDMDGVKARLEAYDRVLKPETQRGIHAHHNLALGVANSIVAAQCGAVRIDASLTGMGAGAGNAPLEVFIAAADRKGWNHGCDVMMLMDAAEDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHAEKAAETYGLDTRTILVELGRRKMVGGQEDMIVDVALDMLKEQQA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: RRAAH_VIBVY
Sequence: MKDITPDICDQHEDKVTLLNLPLQNFGQKAAFFGEIVTVRCYHDNSKVRDVLSENGKGKVLVVDGHGSCQKALLGDQLAILAIENDWEGVIVFGAVRDVAQMSQMELGIKALGTSPFKTEKRGAGEVNVTLTMHNQMVQPKDYIYADWNGILISKELLQF
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: IF6_ARCFU
Sequence: MKVAVNGNPLIGLYAKVSEEYAVVGVNHEPLIDAIQEKLDVDVIVTKIAGSELVGAMMALNSRGAVVSDQVLSSELRELEKSLDVLVIETPMTCFGNNLLINDRGGIANPEMESSVVEKVADFMDIELVKGTVGGIKTVGMAAVVTNRGGLANPNINEWEAKKLQEVAGVEVLTGTVNFGTDMVGSGLVANSKGYVVGRDTTGFELGIVEEALFP
What is the function of this protein?
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
What are the official names of this protein?
Translation initiation factor 6, aIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
Protein: HIS2_ALCBS
Sequence: MSDILSELHQVLESRKGANPDSSYVASLYAKGLNKILEKVGEEAIETILAARDAEVSGEHQALISETADLWFHSLVMLAKLGEHPDKVLAELQRRFGLSGHDEKAARSGKH
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1207_BACAC
Sequence: MLQALLIFVLQIIYVPILTIRTILLVKNQTRSAAAVGLLEGAIYIVSLGIVFQDLSNWMNIVAYVIGFSAGLLLGGYIENKLAIGYITYQVSLLDRCNELVDELRHSGFGVTVFEGEGINSIRYRLDIVAKRSREKELLEIINEIAPKAFMSSYEIRSFKGGYLTKAMKKRALMKKKDHHVS
What are the official names of this protein?
UPF0316 protein BAMEG_1207.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRDE2_CAEEL
Sequence: MFRAYGNNGLKNPERISGENPDLYTQTRAAVQQRATTTLKRNEKQKLAVQNDSVFQQVGIGESDSDDDNGGVRIRMSPHRYIDPDDVFTLPEVKKQNALRDAKIAARAAQATAYNTFPSVKSLNGCQDPPETSQQSTSRKRSASNSRSPSRSHSRRYDRDNGRQRSRSREKKRRKKERRRKRSSSRSSSSSRSRDRSSRARDTSSHTLMKMNKPAKYAFLTDEEYRTCDAYISSAFITQTKSDCENYTQGVPKKEIAKCRLSVKFIVGLEHNNILFNNIYGAEYARDKENRPFWEQLDRYLKDVPKETFFRYVPPVGGYWKIRDRVDLLNLDHIDDDVLANDSDNRKDAFTFELEQAKKTFSENVHNIDALIKVISMEEEMCRRNVGSFSSSNPAALAERHQEMVKKAIKADGRNAKLRLMKIELLIKMDPNSPTIIDDFKNLTITFPHEPMVWIKYLDYIQYDSNVYNYKKLKNAFEDCIRQVTGLTNGTLLSHLNAVNDRPLLRMFHLWIYIRYLKWMISCAHTPVVLANIQATFEYNFGLADVEKRTSTNSKEREVRLEEFWESGLPRIGDEGAVGAEKMLKQSEELSDEDIQKLENDDFDILISRTEETIATCLQAQRDVQISWIEVEREMMNIDARVKRTKLKDCELYEDHVDDLETCELWDIIPFDRIRYYEAPGDCANFDFVQPFLELLGVKFLNSTNCFTTTEQIISDWISNDSTVNFYKTPTYTEKKCFEVGNNILKFMLYNRLKLTENNPEYLDKTMVKYLLAMLVTEASEQEKKLNFHSFKLNLKNLVGTFITKHPDIFKRAMLSKITGIVYMEKFVSWWERALKEQEKVVEADERRKNYKEIKMEEGVVDDVKFDVILLKKDKERVQTIRDKIRDMIDIAIPKSTEKLIQSADSSLPTLQLHLYANVLRGRLSILNQNALEETRDVFCKEILGIHTSEFESDEALLLALDQGLNELLEHCKEKDNLESVDSIPELPRAEALCEALKVVAVFVFLDKMAFSRRAVDCLIANAITKFEQFEAKKNDFNRGTYEKYCDQIDLKFITDTLITFFSHKKHRFIYNENFKKLIFQASQAFPCDSKYAKMLGELHSSGRLQVMKLQGFTDSRNSILNAKRDQQFDPELETRLLMNSLTIMFSWMNAANRIGDAGNQILYKNWKREAANTRDPAIWRQVIRVASKLSQKILKDDAYTRARGQCTWALNLHFDYIEAKTVRKNGDLMEMIYLILEQSMGQEHSLFVTDEEYMKTQQEIGLQYSESGR
What is the function of this protein?
Protein of the nuclear speckles that regulates RNA exosomal degradation (By similarity).  Involved in short interfering RNAs-mediated silencing in nuclei (PubMed:20543824).  Functions with nrde-3 in the nuclear RNA-mediated gene silencing (RNAi) pathway to regulate gene expression via inhibition of RNA polymerase II during the elongation phase of transcription (PubMed:20543824).  Required for exogenous RNAi-induced H3K27 methylation (PubMed:26365259).
What are the official names of this protein?
Nuclear exosome regulator NRDE2, Nuclear RNAi defective-2 protein.
What is the protein family that this protein belongs to?
Belongs to the NRDE2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: CSRA_PSYCK
Sequence: MLILTRRVGETLMIGDEVSVTVLGVKGNQVRIGVDAPKDIAVHREEIYQRIQHERTVQSQMQHLEQGSFAPSFDDEDYFNR
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_YERE8
Sequence: MAKEFSRSQRVSQEMQKEIALILQREIKDPRVGMATVSGIELSRDLAYAKVFVTFLNVLTDNADPDTVKNGIKALQDASGYIRTLLGKAMRLRIVPELTFAYDNSLIEGMRMSNLVTNVIKNDVERQVNPGSDEEK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSRA_ALLVD
Sequence: MAIDKHATPMLDQLETGPWPSFISGIKRLRDQHPDARINAVTNDLLGQLEHSYETRKGYWKGGTVSVFGYGGGIIPRFSEVGKVFPSSKEFHTVRVQPPAGNHYTTAMLRQLADTWEKYGSGLITFHGQTGNIMFIGVDTPNTQNFFDEINDYGWDLGGAGPCVRTAMSCVGSARCEMSCTNELKAHRLLVNNFTDDVHRPALPYKFKFKVSGCPNDCQNAIERSDFAVLGTWRDDMKVDQAEVKHYIADKGRQYYIDNVITRCPTKALSLNDDDTLDVNNRDCVRCMHCLNVMPKALHPGDDKGVTILIGGKRTLKIGDLMGTVVVPFKKLETEEDYESLVELAETIIDFWAENGLEHERCGEMIERIGLANFLEGIGIEPDPNMLSHPRQSSYIRMDGWDEAAEEWFARQAEAGR
What is the function of this protein?
Catalyzes the reduction of sulfite to sulfide.  This is the terminal oxidation reaction in sulfate respiration.
What are the official names of this protein?
Sulfite reductase, dissimilatory-type subunit alpha, Dissimilatory sulfite reductase subunit alpha, Hydrogensulfite reductase subunit alpha.
Protein: GHD7_ORYSJ
Sequence: MSMGPAAGEGCGLCGADGGGCCSRHRHDDDGFPFVFPPSACQGIGAPAPPVHEFQFFGNDGGGDDGESVAWLFDDYPPPSPVAAAAGMHHRQPPYDGVVAPPSLFRRNTGAGGLTFDVSLGERPDLDAGLGLGGGGGRHAEAAASATIMSYCGSTFTDAASSMPKEMVAAMADDGESLNPNTVVGAMVEREAKLMRYKEKRKKRCYEKQIRYASRKAYAEMRPRVRGRFAKEPDQEAVAPPSTYVDPSRLELGQWFR
What is the function of this protein?
Probable transcription factor involved in the regulation of flowering time under long day (LD) conditions.  Plays a major role as repressor of flowering.  Controls flowering time by negatively regulating the expression of EHD1 and HD3A.
What are the official names of this protein?
Transcription factor GHD7, Protein GRAIN NUMBER PLANT HEIGHT AND HEADING DATE 7.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMO_GEOMG
Sequence: MKEKVSMVSLGCPKNLVDAEVMLGCLAKDQYEITTDEHEADIIIVNTCSFIGDAKKESIDTILDLADRKHDGRCKLLVVTGCLPQRYQEELATELPEVDIFVGTADYPRIAEIIAEKRGVAEQLRYISDPNYIFDESLPRLKSSPAYTAYLKIAEGCSNCCSYCVIPSLRGALRSRPLDNLLMEARTLVATGTREINLIAQDITAWGRDLPGSPTLEELVRELAKIVGLRWIRLLYAYPDGITDGLIEIIKTEPKVCKYLDIPIQHISDPVLKRMNRRSTEPQIRALIAKIRAEIPEIALRTSLIVGFPGETEEDFRTLLHYVEETQFDRLGVFCYSREEGTPAAGMEDQVSERVKRDRYKKLMKVQARLSFKRNRRLIDTEEEVIVEGYSDETDLLLKGRSSRQAPDIDGQVYITAGNANVGDIVRLRITDSSDYDLIGEIVEE
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPH_GUIAB
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PSMD3_CAEEL
Sequence: MAPKTGETVVEKMEVDEAKQDVPATEPAKDLNAIAVENIKEQLAALDKGEEHLITRVLQVLPKTRKQINDNVLYKLVSSHLSSDAQFAEGMLKYLHYTPAADTEVQPMDTSNVKTKSPKKGVKPVFASPESDCYLRLLVLLHLYAQKKNTEALALGENQLTSIYNFDRRTLDGLAAKTLYFLCVIYEREGRLFDHQGFLNSRLRTATLRNFSESQAVLICWLLRCYLINRQYQSAAHLVSKVAFPDNASNNDLARYMYYQGRIKALQLDYNSAAGYFLQAQRKAPQEGAIGFKQAVQKWVVVIGLLQGEIPDRSVFRQPIYRKCLAHYLDLSRGVRDGDVARFNHNLEQFKTQFEADDTLTLIVRLRQNVIKTAIKQISLAYSRIYIKDIAKKLYITNETETEYIVAKAIADGAIDAVITSDVRDGPRYMQSSETADIYRTSEPQAHFDTRIRYCLELHNQAVKALRYPPKKKIAVETIEQAREREQQELEFAKELADEDDDDF
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 3, 26S proteasome regulatory subunit rpn-3.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S3 family.
Protein: MGSA_LEPIN
Sequence: MKEVSVPAIKRIVLIAHDNRKEDLVNWVKTHREILSKHQLYGTGTTGKLISEETELPVYRFLSGPLGGDQQIGAKIAEGDLDIVIFFWDPLTAQPHDPDVKALLRIAVLYNVPMACNRSTADYMISSPQFTKTYKKILLSYNTKVKKD
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: KTN82_ARATH
Sequence: MAKRGYKLQEFLAHSANVNCLSIGKKTSRLFITGGDDYKVNLWAIGKPTSLMSLCGHTSAVDSVAFDSAEVLVLAGASSGVIKLWDVEEAKMVRAFTGHRSNCSAVEFHPFGEFLASGSSDANLKIWDIRKKGCIQTYKGHSRGISTIRFTPDGRWVVSGGLDNVVKVWDLTAGKLLHEFKFHEGPIRSLDFHPLEFLLATGSADRTVKFWDLETFELIGSTRPEATGVRSIKFHPDGRTLFCGLDDSLKVYSWEPVVCHDGVDMGWSTLGDLCISEGKLLGCSYYQNSVGIWVSDISQIEPYGIGSADKKECVEKILSALDDQSFDRIKSTPRRSSSPDYETKEIKNIYIDSTGGNSAVAHKSGSLSTPATSTGQAGDNKSLVVHSVVPRDSDIGKDSSDSGKESITFSKTKPGMLLRPAYVRKTPTKFDETKKQSVAVGYLKKSGLDGEKKLDTETAFDSEMSGRNPYDADDSIIKSITNKFEQALLPESPTDEAKCMLLKPPRVQRSPSTKYNEARWATSTDSGALDSKKNGLESSRDMDLPTGLRDDRGSNPCEEDIENKSISSRSERVLSPEKAGDELKSLESPGGSKESKSVKVVRGVKVVSGRTRSLVERFERGEKITHSEDKAASATVVHSSNSVEEEPLTASVQTVSMMPTQVMPVKLDQATNSTTVDVPVLSTRRTKSTPVRVMPVVLGRDTSMATDTPPVTSTRPDRTSATNLTSDVSGVTSKRQTRTSPAPVMPMILNQTTKMKSDEPSITSTWPDRTSATDLTSDVSGVISSRQTRTSPAPVMPMKLNQKTKIKSDEPPITSTRPDRPSATNLTSDESPVTSTRQAKTSPAPVTPVILNQRQTTNMKSDEPPVISTRPLRTSSARVMPVILNQASTTYDERPLSSSRSARTSPARIMPMKLNQADNMPSYEPPVALTRSARNSPARVIPVKLNQATNVTADASHIRSRQRFSPTQTLATPAVFDQVTDMTLDETTKTQQSSDILTQKEEPQISGREDDGDIWEILMRTHSEVLNTLQSRLTKLQIVRHFWERSDIKGAIAALRKLSDHSVQADVINILTDKTEILTLDLFSQLAPVLTGLLGSKTERPVNVSLEMLLKLVAVFGTVIQSTVSARRVVGVDLHAEERLQICQSCSAELQKVQKILPLLTRRGGLIARKAQELNLVLQTP
What is the function of this protein?
May participate in a complex which severs microtubules in an ATP-dependent manner (By similarity).  Microtubule severing may promote rapid reorganization of cellular microtubule arrays (By similarity).  Confers precision to microtubule (MT) severing by specific targeting of KTN1 to MT cleavage sites such as crossover or branching nucleation sites (PubMed:28978669).  Together with other KTN80s, regulates cell elongation by modulating MT organization (PubMed:28978669).  Negative regulator of abscisic acid (ABA) responses (PubMed:21421380).  May function as a substrate receptor for cullin-RING ubiquitin ligase 4 complexes (CRL4), a family of E3 ligases involved in protein degradation (PubMed:21421380).
What are the official names of this protein?
Katanin p80 WD40 repeat-containing subunit B1 homolog KTN80.2, DDB1 binding WD40 hypersensitive to ABA 3, DWD hypersensitive to ABA 3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat KATNB1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Present in dynamic discrete particles specifically localized to microtubule (MT) crossovers and branching nucleation sites.
Protein: CBPC4_HUMAN
Sequence: MAEQEASGLQVLLHTLQSSSDKESILTILKVLGDLLSVGTDRRIHYMISKGGSEALLQTLVDTARTAPPDYDILLPLFRLLAKVGLRDKKIGRKALELEALDVTLILARKNLSHGQNLLHCLWALRVFASSVSMGAMLGINGAMELLFKVITPYTRKRTQAIRAATEVLAALLKSKSNGRRAVNRGYVTSLLGLHQDWHSHDTANAYVQIRRGLLLCLRHIAALRSGREAFLAAQGMEILFSTTQNCLDDKSMEPVISVVLQILRQCYPTSPLPLVTASSAYAFPVPGCITTEPPHDLPEEDFEDDGDDEVDKDSDTEDGKVEDDDLETDVNKLSSKPGLDRPEEELMQYEVMCLELSYSFEELQSKLGDDLNSEKTQYANHHHIPAAASSKQHCYSKDQSSCGQEREYAVQTSLLCRVKTGRSTVHLGSKKNPGVNLYQNVQSNSLRRDSSESEIPDIQASPKADAWDVDAIFCPRMSASFSNSTRTREVVKVIDKLLQTHLKRVPFHDPYLYMAKARRTSSVVDFKMMAFPDVWGHCPPPTTQPMLERKCGVQRIRIFEDIRRLIQPSDVINKVVFSLDEPWPLQDNASNCLRFFSKFESGNLRKAIQVREFEYDLLVNADVNSTQHQQWFYFKVSGMQAAIPYHFNIINCEKPNSQFNYGMQPTLYSVKEALLGKPTWIRTGHEICYYKNHYRQSTAVAGGASGKCYYTLTFAVTFPHSEDVCYLAYHYPYTYTALMTHLDILEKSVNLKEVYFRQDVLCQTLGGNPCPLVTITAMPESNSDEHLEQFRHRPYQVITARVHPGESNASWVMKGTLEFLVSSDPVARLLRENFIFKIIPMLNPDGVINGNHRCSLSGEDLNRQWLSPSAHLQPTIYHAKGLLYHLSSIGRSPVVFCDFHGHSQKKNVFLYGCSIKETLWQAACTVGTSTILEEVNYRTLPKILDKLAPAFTMSSCSFLVEKSRASTARVVVWREMGVSRSYTMESSYCGCNQGPYQCTQRLLERTKNERAHPVDGLQGLQFGTRELEEMGAMFCLGLLILELKSASCSHQLLAQAATLLSAEEDALDQHLQRLKSSNFLPKHIWFAYHFFAITNFFKMNLLLHVSPVCDT
What is the function of this protein?
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins.  Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein.  Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate.  Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK.
What are the official names of this protein?
Cytosolic carboxypeptidase 4, ATP/GTP-binding protein-like 1, Protein deglutamylase CCP4.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CE12C_MAGO7
Sequence: MIKTLTAAITLLAAGGVVAVPHPVANEKPTRTQPLSKRATTVCGQWDSVQTGGYTVYNNLWGKDSGTGSQCLTVDGVSSGLLSWSTTWSWSGGQYNVKSYPNAVVSAPAARLSAISSIPTRWQWSYTGNSMVANVAYDLFTNSNCGTTPEYEIMVWIGAYGGAGPISQSGQPIASPNIGGVTWRLYKGSHSQMTVFSFVSPGQITNYSGDLVNFVRYLTQSQGMPASQCLYSAGAGTEPFTGSNARFTTSGYSMSISTSGSGGGEGGGGPNPPSCAALYGQCGGSGWSGPTCCTQGTCKAANQWYSQCS
What is the function of this protein?
Endoglucanase that hydrolyzes 1,3-1,4-beta-glucan.
What are the official names of this protein?
Endoglucanase cel12C, Cellulase cel12C, Endo-1,4-beta-glucanase cel12C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 12 (cellulase H) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCIC_ECO55
Sequence: MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPSDAQLAQLNDGVPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVILIIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLALAPVMLVQDKMGIFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEIGAVLANTLSNLISAILLIYLFRLYMLIRQ
What are the official names of this protein?
UPF0259 membrane protein YciC.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTLY_THESQ
Sequence: MRFSRVVSLVLLLVFTAVLTGAVKASLNDKPVGFASVPTADLPEGTVGGLGGEIVFVRTAEELEKYTTAEGKYVIVVDGTIVFEPKREIKVLSDKTIVGINDAKIVGGGLVIKDAQNVIIRNIHFEGFYMEDDPQGKKYDFDYINAENSHHIWIDHCTFVNGNDGAVDIKKYSNYITVSWCKFVDHDKVSLVGSSDKEDPEQAGQAYKVTYHHNYFKNCIQRMPRIRFGMAHVFNNFYSMGLRTGVSGNVFPIYGVASAMGAKVHVEGNYFMGYGAVMAEAGIAFLPTRIMGPVEGYLTLGEGDAKNKFYYCKEPETRPVEEGKPAFDPHEYYDYTLDPVDDVPKIVVDGAGAGKLVFEDLMSSK
What is the function of this protein?
Cleaves unsaturated trigalacturonate from pectin.  Activity is highest towards polygalacturonic acid, activity on methylated pectins decreases with an increasing degree of methylation (By similarity).
What are the official names of this protein?
Pectate trisaccharide-lyase, Pectate lyase A, PelA.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.