PharMolix/UniProtQA huggingface dataset:
Protein: NOGG2_DANRE
Sequence: MGSITRALPLLLLLLLCAHGTASQHHLRLRPLPSEGLPVPDLIENPDPEHDPREQDLSEKTLLKKLGSNFDANFMSIHLPAQLNASAPPELPRLPMPAELKKLDLTETPYGRRVKVGKKARRKFLQWLWMYTHCPVLYTWKDLGLRFWPRYIKEGNCFSERSCSFPEGMSCKPVKAVTKTFLRWYCQGFMRQKYCTWIQVQYPIISQCKCSC
What is the function of this protein?
Inhibitor of bone morphogenetic proteins (BMP) signaling.
What are the official names of this protein?
Noggin-2.
What is the protein family that this protein belongs to?
Belongs to the noggin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPR_CLOPE
Sequence: MYNVRTDLAVESREIYKHRYNREIDGVVFEEKTVEEDIKVTNVDILNEEGAKAMEKPIGRYVTIDIPEYTHYDGGIMDEVSHVVAASLEELINLPEERTALVVGLGNWNVTPDAIGPKVVGKLMVTRHLKKVMPDIIDDSVRPVCAIAPGVLGITGIETGEIIKSLVEKIKPDLVVCIDALASRKLERVARTIQISNTGISPGAGVGNHRMQINEESLGIPVIALGVPTVVDAATIANDAMDLVLDEMINQADAGKEFYNILNNIDKNEKGMMIKSLLDPYVGDLMVTPKEIDDIIESVSKIIANGINIALQPNMVLEDINKFLN
What is the function of this protein?
Initiates the rapid degradation of small, acid-soluble proteins during spore germination.
What are the official names of this protein?
Germination protease, GPR endopeptidase, Germination proteinase, Spore protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A25 family.
Protein: RL1_LIBAS
Sequence: MVSKISKRMQQISQGIDRSALYGLSDAVVMLKERATARFDETVEIAMNLGIDPRHANQMVRGVVTMPNGTGVNVRVAVFATSSKADEAREAGADIVGGEDLFEIVKGGQIDFDRCIATPDMMPLVGRLGRILGPRGIMPNLRVGTVTTDVATAVRESKSGAVDFRSEKAGIIHAGIGKVSFENKKIEENVLAFVSAVVKAKPSVAKGDYVKRVTLSSTMGCGIKVDLSSFSV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LDL3_ORYSJ
Sequence: MSDQPPPYTPLPLLSSFPPNPYPDQTPDPASTPTLVLPNPAFPNKRKRTGFRRKLPSGSPAAPVAVAASPSAQPPPRASAADDIIVINREPTAEAVTALTAGFPADSLTDEEIEAGVVSDVGGIEQVNYILIRNHLLTRWRETFNSWLAKESFATLIPPHCDHLLNAAYSFLVSHGHINFGVAPAIKERIPKEPTRHNTVIVVGAGLAGLAAARQLVAFGFKVVVLEGRKRCGGRVYTKKMEGGGRSAAGDLGGSVLTGTFGNPLGIVAKQLGLPMHKIRDKCPLYRPDGSPVDPEVDKKVEGTFNKLLDKSSLLRASMGDVAMDVSLGAALETLRQTDGDLSTDQEMNLFNWHLANLEYANAGLLSKLSLAFWDQDDPYDMVGDHCFLPGGNGRLVQSLAENVPIVYERTVHTIRYGGDGVQVVVNGGQVYEGDMALCTVPLGVLKNGGVKFVPELPQRKLDSIKRLGFGLLNKVAMLFPHVFWSTDLDTFGHLTEDPSHRGEFFLFYSYATVAGGPLLMALVAGEAAHNFETTPPTDAVSSVLKILRGIYEPQGIEVPDPLQSVCTRWGTDSFSLGSYSHVAVGASGDDYDILAESVGDGRLFFAGEATTRRYPATMHGAFISGLREAANITLHANARAAKSKVEKGPSTNTQACAALLMDLFRQPDLEFGSFSVIFGGQASDPKSPAILKVELGGPRKKGATEGGKADQHHSNKLLFQQLQSHFNQQQQLYVYTLLSRQQAMELREVRGGDEMRLHYLCEKLGVKLVGRKGLGPGADAVIASIKAERNSSRTKTRPSKLKIGIPKSKS
What is the function of this protein?
Probable histone demethylase.
What are the official names of this protein?
Lysine-specific histone demethylase 1 homolog 3, Flavin-containing amine oxidase domain-containing protein 3, Protein FLOWERING LOCUS D-LIKE, Protein LSD1-LIKE 3.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: GAS1_YEAST
Sequence: MLFKSLSKLATAAAFFAGVATADDVPAIEVVGNKFFYSNNGSQFYIRGVAYQADTANETSGSTVNDPLANYESCSRDIPYLKKLNTNVIRVYAINTTLDHSECMKALNDADIYVIADLAAPATSINRDDPTWTVDLFNSYKTVVDTFANYTNVLGFFAGNEVTNNYTNTDASAFVKAAIRDVRQYISDKNYRKIPVGYSSNDDEDTRVKMTDYFACGDDDVKADFYGINMYEWCGKSDFKTSGYADRTAEFKNLSIPVFFSEYGCNEVTPRLFTEVEALYGSNMTDVWSGGIVYMYFEETNKYGLVSIDGNDVKTLDDFNNYSSEINKISPTSANTKSYSATTSDVACPATGKYWSAATELPPTPNGGLCSCMNAANSCVVSDDVDSDDYETLFNWICNEVDCSGISANGTAGKYGAYSFCTPKEQLSFVMNLYYEKSGGSKSDCSFSGSATLQTATTQASCSSALKEIGSMGTNSASGSVDLGSGTESSTASSNASGSSSKSNSGSSGSSSSSSSSSASSSSSSKKNAATNVKANLAQVVFTSIISLSIAAGVGFALV
What is the function of this protein?
Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.  Involved in cell wall biosynthesis and morphogenesis.
What are the official names of this protein?
1,3-beta-glucanosyltransferase GAS1, Glycolipid-anchored surface protein 1, Glycoprotein GP115.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 72 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as GPI-anchored plasma membrane protein (GPI-PMP) as well as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer.
Protein: CUL3A_XENLA
Sequence: MSNLGKSTGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNRDKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHMFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA
What is the function of this protein?
Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity).  Involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division (By similarity).  May play a role in the regulation of mittotic entry via ubiquitination of aurka (By similarity).
What are the official names of this protein?
Cullin-3-A, CUL-3-A.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAJ_FRATU
Sequence: MQQKCYYEILNISKTASGVEIKRAYRKLAMKYHPDRNPGDKEAEIKFKEISEAYEILSDDSKRSRYDQFGHAGVNQQSGFGGTGGFEDIFDTFFGGGTSRGSNRSRASRGSDLEYTLEITLEEAFFGVEKEITIPRMESCDSCDGTGSKSRSKTTCHACHGQGTIRRQQGFFAFEQTCPVCNGTGYSITDPCDACYGNGKVKKQKTLKVKIPEGVDNGDRIRLQGEGDSGSNGAMNGDLYVQIIIKEHKIFERRDINLYCEMPISFTKACLGGDIKVPTLDGEVVLKVVPETQTGKVFRLREKGMKSLRGHRRGDLLCKVVVETPVNLSAEQKELLEKFADSLGEDYQSKHAPKSKTWFDNVKDYAKKFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT_LISMO
Sequence: MFKKLFRQDENILNSELAEDLPIPRHVAIIMDGNGRWAKKRFLPRIAGHKEGMDVVKRVTRYANAIGIDVLTLYAFSTENWKRPTDEVDFLMKLPVEFFDSFVPELIEENVRVNVMGYRENLPDHTMRAVEKAIADTAHCTGLTLNFALNYGGRSEIITAAKEAMKELELEGKSADDLTEEKLNDHLMSSGLGDPDLLIRTSGELRLSNFMLWQLAYSEFYFTDTHWPDFSKEDFLQAIIEYQNRSRRFGGL
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: Y2395_YERE8
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPGANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDEDNNMETIIYEGYGPGGTAVMVECLSDNRNRTVSEVRHAFTKTGGNLGTDGSVSYLFTKKGVISYAPGLEEDAVMDAALEAGADDIVVYDDGAIDVFTAWESLGAVKDALDATGLVAEGAEVSLIPSTKAELDAETAPKLLRLIDMLEDSDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YE2395.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_BEUC1
Sequence: MLRWLTAGESHGPALVAVLEGLPAGVEITTTQIGDALARRRLGYGRGARMSFERDEVRLLGGVRHGLTQGGPIAVEIGNTEWPKWETVMAADPVDPAALTGARGAPLTRPRPGHADLIGMTKYGFDEARPVLERASARETASRVALGRVAAAFLEQAAGVRLVSHVVAIGPVSAPDDADLPTPDDVAALDADPIRCFDAATSAAMVAEIDDAQKAGDTLGGVVEVLAYGLPPGLGSYVQSDRRLDGRLAGVLMGIQAIKGVEVGDGFRTAARRGSAAHDEIERATDGRVRRRTNRAGGVEGGMTNGEVLRVRAAMKPISTVPRALDTIDTATGDAAKAIHQRSDVCAVAPAAVVAEAMVALVLAQALLEKVGGDSVAESARNLTSYLEAIPEQQR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CSN8_HUMAN
Sequence: MPVAVMAESAFSFKKLLDQCENQELEAPGGIATPPVYGQLLALYLLHNDMNNARYLWKRIPPAIKSANSELGGIWSVGQRIWQRDFPGIYTTINAHQWSETVQPIMEALRDATRRRAFALVSQAYTSIIADDFAAFVGLPVEEAVKGILEQGWQADSTTRMVLPRKPVAGALDVSFNKFIPLSEPAPVPPIPNEQQLARLTDYVAFLEN
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.  The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases.  CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
What are the official names of this protein?
COP9 signalosome complex subunit 8, SGN8, Signalosome subunit 8, COP9 homolog, hCOP9, JAB1-containing signalosome subunit 8.
What is the protein family that this protein belongs to?
Belongs to the CSN8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPOC_PROA2
Sequence: MIFSQGSSPFKGDFSKIKFSIASPESVLAHSRGEVLKPETINYRTFKPERDGLMCEKIFGPTKDWECYCGKYKRVRYKGIICDRCGVEVTMKSVRRERMGHISLAVPVVHTWFFRSVPSKIGALLDLSTKELERIIYYEVYVVINPGDPGEKQGIKKLDRLTEEQYFQIITEYEDNQDLDDDDPAKFVAKMGGEAIHTLLKGLNLDESAVGLRKVLKESGSEQKRADALKRLKVVEAFRKSYEPQKKTRKKPGGLFPEDEMPEPYIFEGNKPEYMVMEVIPVIPPELRPLVPLEGGRFATSDLNDLYRRVIIRNNRLKKLIDIRAPEVILRNEKRMLQEAVDALFDNSRKANAVKTGESNRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHECGLPKSMAIELFQPFVIRRLVERGIAKSVKSAKKLIDKKDPIVWDVLEKVIDGRPVLLNRAPTLHRLGIQAFQPTLIEGKAIQIHPLVCTAFNADFDGDQMAVHVPLSQEAQLEASLLMLSSHNLILPQSGKPVTVPSQDMVLGMYYLTKSRIGENGQGNIFYSNEEVLIAHNEERLGLHALVFIKYDGHVEQKFDPVRLLDIISDDESEKKAWLKKEIEAKRLLVTTVGRVIFNQYVPEKIGFVNKVIDKKGAKELISKICSEVGNVQAAEFLDNIKQVGYHYAMKGGLSIGLADAIIPEAKIQLIKKATKESNKILREYNRGTLTENERYNQIVDVWQKVTNLVAEESYQKLRKDRVGFNPLFMMLDSGARGSREQVRQLTGMRGLIARPQKSMSGQPGEIIENPIISNLKEGLTVLEYFVSTHGARKGLSDTSLKTADAGYLTRRLHDVAQDVIVTIDDCGTTRGLHVERSIEEETGGQIKFSDKIRGRVASRDIWDTLKDEIVVPAGGIITEDIADAIQANIGVLEADIRSVLTCEAKQGICSKCYGTNLAVHKIVEIGEAVGVIAAQSIGEPGTQLTLRTFHQGGTAQGGIAETETKAVYEGQVEFENIRTVEQETINEDGMPEVRILVIQKNGRINIVDPDSGKVLKRHDVPHGASLHRSVGDLVKKEDVLFSSEPNSTQIIAELEGYVKFADIEKGVTYKEEVDPQTGYVQHVIINWRSKLRASETREPRIMIVSESGEILKTYPVPIKSNLFVEDNKKVSIGDILAKVPRNLDRVGGDITAGLPKVTELFEARIPSDPAIVSEIDGYVGFGSQRRSSKEIKVKNEFGEEKTYYVQVGKHVLANEGDEVTAGEPLTDGAISPQDILRIQGPNAVQQYLVNEIQKVYQINAGVEISDKHLEVIVRQMLQKVRVEEPGDTELLPGDLIDRTVFIEANTAIAEKVRVIDKGDAPARIQEDQLYKLKEITKLNRELRKNSKSLIVVEPAIQATSHPVLLGITSAALQTESVISAASFQETTKVLTDAAVAGKIDNLLGLKENVIVGKLIPAGTGLKAYRKLELNKVYPEAAEIAVPEVDEAAPASSDDDAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: AFB3_ARATH
Sequence: MNYFPDEVIEHVFDFVASHKDRNSISLVCKSWHKIERFSRKEVFIGNCYAINPERLIRRFPCLKSLTLKGKPHFADFNLVPHEWGGFVHPWIEALARSRVGLEELRLKRMVVTDESLDLLSRSFANFKSLVLVSCEGFTTDGLASIAANCRHLRELDLQENEIDDHRGQWLNCFPDSCTTLMSLNFACLKGETNVAALERLVARSPNLKSLKLNRAVPLDALARLMSCAPQLVDLGVGSYENEPDPESFAKLMTAIKKYTSLRSLSGFLEVAPLCLPAFYPICQNLISLNLSYAAEIQGNHLIKLIQLCKRLQRLWILDSIGDKGLAVVAATCKELQELRVFPSDVHGEEDNNASVTEVGLVAISAGCPKLHSILYFCKQMTNAALIAVAKNCPNFIRFRLCILEPHKPDHITFQSLDEGFGAIVQACKGLRRLSVSGLLTDQVFLYIGMYAEQLEMLSIAFAGDTDKGMLYVLNGCKKMRKLEIRDSPFGNAALLADVGRYETMRSLWMSSCEVTLGGCKRLAQNSPRLNVEIINENENNGMEQNEEDEREKVDKLYLYRTVVGTRKDAPPYVRIL
What is the function of this protein?
Confers sensitivity to the virulent bacterial pathogen P. syringae (By similarity).  Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription.  Involved in embryogenesis regulation by auxin.
What are the official names of this protein?
Protein AUXIN SIGNALING F-BOX 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIPB_DESPS
Sequence: MSFLVDLGATSYIACYATQQAVVARRCSGDLDRDCFLLTEHPPVYTLGKRGGEQHLHISKEMLAQKGIDVVSIERGGEITYHGPGQLVLYPILHLRKRKMRVTEYVGLLEETMIRLAADFGVRVVRNTRNAGVWTEDGRSKIGSIGIAIRHGVSFHGFAFNLNTDLEPFSWINPCGLTGVTATSLAREAGTDFDPAEVKKRLLSIVADLFGEFTVVDSLHSVK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCHS_ECOLI
Sequence: MVVGEGLLSAARFALRVVACGNALSLALKSNLGRSFSSFPAWAEYLIADSFENSGAFESDGGGGRITQRCALRPSGRCLRQRSLADARAEP
What are the official names of this protein?
Protein YchS.
Protein: KDGD_XANCP
Sequence: MSSRYTPSEMAQALGAGLLSFPVTHFDADMAFDEPAYRSNLDWLSSHPAAGLFAAGGTGELFSLTLDEVDRAVRAAVTQTAGRMPVIAPAGYGTAIAVAMAQAAERNDADGILLFPPYLTECDADGVAEHVERVCKATSLGVIVYGRANARLDDVALARVAERCPNLVGYKDGIGDVERMTRIYARLGDRLLYVGGLPTAETFALPYLEMGVTTYSSAIFNFLPEWALSFYAAVRARDHATIYRELNDFVLPYTVLRNRRAGYAVSIVKAGMRAVGRPAGPVRTPLADLTEDEFAQLTQLIGGRR
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: TRPB_BACP2
Sequence: MYAYPNELGRYGEFGGKFVPETLMQPLKEIEQAFNELKEDPAFEQEYLSLLHNYSGRPTALTYADQLSAYLGGAKIYLKREDLNHTGAHKINNALGQALLAKKMGKSNIIAETGAGQHGVAAATVAAKFGLSCTVFMGKEDVERQSLNVFRMKLLGAEVIPVTSGNGTLKDATNEAIRYWVQHCSDHFYMIGSVVGPHPYPQIVSEFQRMIGDEAKEQMLKKEGRLPHKVIACVGGGSNAIGMYRAFLDDEVDLIGVEAAGKGIDTPLHAATITKGTKGVIHGSLTYLIQDEFGQIIEPYSISAGLDYPGIGPEHAYLHASGRVQYVSATDQEALDALKLLTEKEGILPAIESAHALAKAFEMSRTMSEDEIILVCLSGRGDKDVHTLMNVLESEGKTK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: GERDS_LAVAN
Sequence: MEIHSSVVPAITNVKSLDEIRRSAKFHPTVWGDYFLAYNSDNTEITAAEHEEHAKQKEMVKKLLTLAPNDPTDKMQLIDAIQRLGLQYHFEKEIQEILQSIHANFKADKDLHTVALRFRLLRQHGYNVACDVFNNFLNKEGDFMESITNDFEGLLSLYEAAYLGTHGEEILDKAIEFCSFHLQSSLPQISNVSLSKRVEEALYIPTHKSLTRFGARKFIPIYEEDESHKKVLLNLAKLDFNIVQKIHQKELSDLTRWWTKLEVPKNMPYSRDRLVELFFWIVGVYFEPQFTTARRILVKAISMASLIDDTYEHATLDELKVLTDVIERWDTNAVIKDWPPYTQMCYKYLFDTYAEIEDEVEERESYRVQYAKKEMQKLVRAYFDEAKWLYKNYLPTWEEYMKVSTVTGAYMMLSTTSLVGMGDLVTKQDFDWVVREPLIVRASSVISRLMDDLVGDEDEQKPSGALCYMKQYGVSKEEACAEVRKHVKNAWKDMNQECLEPRPASMQVLTRVVNLGRVINLLYTGDDWYGNPLGSKEWVKMVFVEPLTI
What is the function of this protein?
Sesquiterpene synthase that catalyzes the formation of sesquiterpenes and sesquiterpenoid alcohols (PubMed:24078339).  Converts farnesyl diphosphate (FPP) to germacrene D (PubMed:24078339).  Converts FPP to bicyclogermacrene (PubMed:24078339).  Germacrene D is the major product (PubMed:24078339).
What are the official names of this protein?
Germacrene D synthase, LaGERDS, (-)-germacrene D synthase, Bicyclogermacrene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: PTPA2_DICDI
Sequence: MSENNNKIPSFGLKSNVNSTYNHLETVAKLSIDEKLVNEPPKFVDIKTITPLNVENNGIAQKRIISKRDLRSFHTSSTYSELLNFIIQLSLDIQGKSLKSNFTITKNINSIIVLLNQLDQYITDIPPKQIRTRFGNESFVEWFNKVEKETPKLLFNLINDNPLNTPITNEVPIIYNEISTYLQNSWGDKQRIDYGSGHELNFICFLLCLVKIKFIKREEYELLVLIIFNKYLNMMRRLQESYWLEPAGSHGVWGLDDYHFLPFLFGSSQLIEHKYIRPKSIRNDEIVNSSFSDEYMYLGCIRFIGKVKSGGSLLEHSPMLVDISGVKNWSKVNEGMIKMFKSEVLGKLPIMQHMFFASIIQYIDNPDIIETDEEINQRKPIVTHSFSSCGCINRVPSMFAVANTDKILASTSTTTNNNNNNITSGDHCNDNEQQCSETHNHDHNHNHNHNHNHPPPPPQQQRSYFPLD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase (By similarity).
What are the official names of this protein?
Probable serine/threonine-protein phosphatase 2A activator 2, Peptidyl-prolyl cis-trans isomerase PTPA-2, PPIase PTPA-2, Rotamase PTPA-2, Phosphotyrosyl phosphatase activator 2.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_CUPNH
Sequence: MAFQECVIEVAQDQAEAWSDALFDLGALSVSVEDADADTPDEQPLFGEPGLEPKQLAWNRSRVVALFGDDADPAVVVAAAANQLGIDPVPAYQLRAVEDQDWVRLTQSQFEPIRIGERIWVVPSWHDAPEPDAVVLELDPGLAFGTGSHPTTRLCMQWLEQNLKPGETVLDYGCGSGILAIVARKLGAGDTVGIDIDPNAVEASRYNAERNRVEASFALPESVSEASYDLVVANILSNPLKLMAAMLSARVRAGGRLVLSGVLERQADEVAAAYAPWLPLTVWRSEEGWVCLHGTRGAQP
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COLI_NEOVI
Sequence: SEPGRREGKRSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEFKRELAGERPEPALGPEGAAEGMAALADLEYGLVAKAEVAEKKDDGPYKMEHFRWGSPGKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ
What is the function of this protein?
Endogenous opiate.
What are the official names of this protein?
Pro-opiomelanocortin, POMC, Corticotropin-lipotropin.
What is the protein family that this protein belongs to?
Belongs to the POMC family.
What are the subcellular locations of this protein?
Secreted. Note=Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms.
Protein: PLSY_CITK8
Sequence: MSAIAPGMILFAYLCGSISSAILVCRIAGLPDPRQSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYALGVTPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKLKKKREKDPQ
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSP_BURCM
Sequence: MKLEHPDRLMNRTPLSLAALETHDAFAERHIGPDAASQQAMLDTLGFASRAALIDAVIPASIRRAETLPLGPFAQPKSEAEALAALRALADKNQVFRSYIGQGYHDTHTPAVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQQMVADLTGLAISNASLLDEATAAAEAMTLLQRTGKPASNVFYVADDVLPQTLEVIRTRALPVGIEVKTGPAADAAQANAFGVLLQYPGVNGDVRDYRALTEAIHAAGGHVVVAADLLALTVLTPPGEWGADVAVGNTQRFGVPMGFGGPHAAYLAVRDEFKRQMPGRLVGVTVDAQGKPALRLALQTREQHIRREKATSNVCTAQALLAIMASMYAVYHGPHGLKTIALRVNRIAALFAAGVKQLGFAPINDTFFDTLTIDTGARTAQVHEFAKARRINLRRVSDTQVGVSFDETTTRDDLAALLAVFAQAAGGTAPSVDALDAGLAGVAALPAGLERTSAYLTHHVFNRHHSETEMLRYLRSLSDKDLALDRSMIPLGSCTMKLNATSEMLPVTWPEFGRIHPFAPAEQTVGYREMIDQLEQMLVAATGYAAVSLQPNAGSQGEYAGLLIIHAYHASRGEAHRDVCLIPASAHGTNPASAHMAGMKVVVVACDAQGNVDIADLKAKAEQHANDLAAIMITYPSTHGVFEQNVREICEIVHAHGGQVYVDGANMNAMVGLTAPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGPHLAKFLPNQRSTGYTREENGIGAVSAAPYGSASILPISWMYIAMMGAKNLTAATETAILNANYIAKRLAPHYPVLYSGPGGLVAHECILDLRPIKETSGISVDDVAKRLMDYGFHAPTMSFPVPGTLMVEPTESESQEELDRFIAAMIAIREEIRAVEEGRADREDNPLRHAPHTAAVVTANEWPHAYSREQAAYPVASLGTNKYWPPVGRADNAYGDRNLFCSCVPMSDYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.