PharMolix/UniProtQA huggingface dataset:
Protein: CDN1B_CRIGR
Sequence: MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVNHEELTRDLEKHCRDMEEASQRKWNFDFQNHNPLEGRYQWQEVDKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRQAVPSIGSQAYSEDRHLVEQMPDPTDSPAGLAEQCPGMRKRPAADDSSSQNKRANRTEENVSDGSLNAGSVEQTPKKPGLRRHQT
What is the function of this protein?
Important regulator of cell cycle progression.  Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA.  Involved in G1 arrest.  Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes.  Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation.  Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1.
What is the protein family that this protein belongs to?
Belongs to the CDI family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endosome. Note=Nuclear and cytoplasmic in quiescent cells. AKT- or RSK-mediated phosphorylation on Thr-198, binds 14-3-3, translocates to the cytoplasm and promotes cell cycle progression. Mitogen-activated UHMK1 phosphorylation on Ser-10 also results in translocation to the cytoplasm and cell cycle progression. Phosphorylation on Ser-10 facilitates nuclear export. Translocates to the nucleus on phosphorylation of Tyr-88 and Tyr-89 (By similarity). Colocalizes at the endosome with SNX6; this leads to lysosomal degradation (By similarity).
Protein: NSP3_ROTSH
Sequence: MLKMESTQQMAVSIINSSFEAAVVAATSALENMGIEYDYQDIYSRVKNKFDFVMDDSGVKNNLIGKAITIDQALNNKFGSAIRNRNWLADTSRAAKLDEDVNKLRMMLSSKGIDQKMRVLNACFSVKRIPGKSSSIIKCTKLMRDKLERGEVEVDDSFVDEKMEVDTIDWKSRYEQLEQRFESLKSRVNEKYNNWVLKARKMNENMHSLQNVISQQQAHIAELQVYNNKLERDLQNKIGSLTSSIEWYLRSMELDPEIKADIEQQINSIDAINPLHAFDDLESVIRNLISDYDKLFLMFKGLIQRCNYQYSFGCE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: AACUB_ASPA1
Sequence: MDTPISASNQTATVVKPQQPRRVLACVLCQQRKIKCDRTFPCTNCVRAHVQCEQATRQRRRRFPEKELLTRLRLYESLLQQHNIKFDPLHTPTADHRSASDDGRDDLPEGAESEGTFGEREKPAVKTKSLYEFGSCINSLISGRLILVNRGDDDGNNGEDDEHDTGFLHDTDDVRPAVIQKAWNHTFQGQNNDHLLFGSPVGTVNLSASHPSHVHIFRLWQVYLDNVNPLLKVTHTPTLQTRIIDAASDITNISPTLEALMFSIYCVSLLSLSDEQCRALFGSAKKELSTGYQFACQQALRSCSILRSSDRESLTALYLYLVSIRPDTDPASLSSLLSVAIRIAQRIGIHNESTYGKCSALETEMRHRLWWSLIIFDNRICEMSDDKTASLAPTWDCKVPLNVNDFELQPEMKTPPAPNNRPTEMLFAVVRSELADFVRHSAFHLNFTNPSLNTIATRLTDETAQLVSLERALEEKYLAFCNPENALHFMTLWTMRGSLAKSRLLQHYSQCSNTSVPPTDAQRNTGIAHALRMLECDTELMTSPLTQGYRWLVHFHFPFPAYIHLLQDLKKRPVEAHADRAWEAMSDNYAVRMMDASQDDRPFFIVFSRIVLQAWEAREKMAVAAQLETPPPVPPRMVVDIRDKVMQMTASFGMDAAAAVESGGVVGVKAGDLDMPMQMDFAAPEMAYGAGGHGATGLEPWGCLDMAGPAAGDVGANQFLLNTMEWNALHARDR
What is the function of this protein?
Transcriptional regulator; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer secalonic acid D.
What are the official names of this protein?
Transcriptional regulator AacuB, Secalonic acid biosynthesis cluster protein B.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNE_BUCBP
Sequence: MRRMLINAIEIKKLRIALIDGQQLYDLNVENIDKKQRKSNIYKGKIVRIEPSLEAAFVDYGEKKNGFLPLKEISRNYFPNNCSNYRHLHIKNILKEGQECIVQIDKEERGTKGALLTTFISLAGNYLVLMPNCPHLEGISRKIEGIDRFHLKKIISMLMVPENMGIIIRTSGVGRSIETLQLDLNFRVKNWYTIKKSAEINTAPCLIHKESNIVIRTLRDYLKKDIQEIIVDNPEILELARDYMFNMNCSYFEKKIKLYTGSDPLFSYYKIESQINALLRRIVKLPSGGSIIIDYTEALTAIDINSSQSTKGVNIEETAFNTNYEAVREIARQLRLRDLGGLIVIDFIDMSVLKHQKMIELHLHQVLQKDRARVQVGSISQFGLLEMSRQCLGSPLKKINHNYLFEMQKC
What is the function of this protein?
Endoribonuclease that plays a central role in RNA processing and decay.  Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs.  Also involved in the degradation of most mRNAs (By similarity).
What are the official names of this protein?
Putative ribonuclease E, RNase E.
What is the protein family that this protein belongs to?
Belongs to the RNase E/G family. RNase E subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y007_NPVAC
Sequence: MAVIFNNKQLLADNSIEKGGELFLFNGSYNILESYVNPVLLKNGVIELEEAAYYAGNILYKTDDPKFIDYINLIIKATHSEELPENSTVVNYRKTMRSGTIHPIKKDIYIYDNKKFTLYDRYIYGYDNNYVNFYEEKNEKEKEYEEEDDKASSLCENKIILSQINCESFENDFKYYLSDYNYAFSIIDNTTNVLVAFGLYR
What is the function of this protein?
May have a role in tissue tropism within the insect larvae.
What are the official names of this protein?
Uncharacterized 23.6 kDa protein in LEF2-PH intergenic region, ORF603.
Protein: COXX_RHOP5
Sequence: MSVIESHDLGLIAPRISEAGVADYVALLKPRVMSLVIFTALVGLLLAPGSFHPVLAITSILCIGVGAGAAGALNMWYEDDIDAKMTRTANRPIPRGKITRPEALTFGMTLAFFSVVTLGILVNWIAAALLAFTIFFYVVIYTIWLKRVTAQNIVIGGAAGALPPVVAWAAVTGSVSVEPMLLFAIIFFWTPPHFWALALFRAGDYANAGVPMLPVTAGPDATRLQILLYTIALVAVALAPWPLGYFSAVYGITSLALGGGMLACALRVYRHRTGSAALRASRNLFRFSILYLFALFAVLLLEVVARGVLALFG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROFA_ORYSJ
Sequence: MSWQTYVDEHLMCEIEGHHLTSAAIVGHDGTVWAQSAAFPQFKPEEMTNIMKDFDEPGFLAPTGLFLGPTKYMVIQGEPGAVIRGKKGSGGITVKKTGQALVVGIYDEPMTPGQCNMVVERLGDYLVEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).  May serve as a modulator in pollen germination and pollen tube growth.
What are the official names of this protein?
Profilin-A.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RNPH_IDILO
Sequence: MRPSGRTAQQIRPVTITRNFTKHAEGSVLIEFGETKVLCNASVERGVPRFLKGKGQGWVTAEYSMLPRATHTRSAREASRGKQGGRTLEIQRLIGRSLRTCIDMSALGEHTITIDCDVIQADGGTRTASITGACVALVDALNWMRAQGMVKVNPLKEMVAAISVGILDGEPVSDLEYIEDSKADTDMNIVMTEAGKFIEIQGTAEGEAFSFDEMNSLVEMARHSIRELIDIQKQALA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: REX_STAAS
Sequence: MSDQVKIPRATLKRLPLYYRFVSSLKSKGIDRVNSKAISDALQIDSATIRRDFSYFGELGKKGYGYNIDSLLDFFKSELSESDMIKIAIVGVGNLGKALLTYNFSIHDDMTITEAFDVKEDVIGQKIGNVIVKDNDELITTLKKEEIDVVILTTPERVAQKVADELVQAGVKGILNFTPGRINTPSDVQVHQIDLGIELQSLLFFMKNYSE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDA_ACET2
Sequence: MSERTKWTDEQWEAITGNEKSLLVSAAAGAGKTAVLVERIIRKITDEENPVDIDRLLVVTFTNAAATEMRERIAQAISEKLEENPGSANIQRQLTLLGKACITTIHSFCLEVIRSNFQQINIDPGFRIADETESRLMKLEALDEVFEEQYENENEDFFELLECYGGNRDDRALQDMVLNLYDFIQSSPWPEEWLEKMTESMNIPDGTDFGKTLWGSVLLSSVKIELEGLKEMISRALEILKDASGLEKYRAVYMEDLANVDALLKLLNEESEMQWDRIFNALQGFEFATLPRCGREVDKDKQEIVKKIRDDVKQRIRKFREKVITSVSNEIISDLKALYPKMKCLANLVKQLAEKYAEKKNRKSVVDFNDLEHFCLEILTERKEDGSIIPSRTAISYRERFAEILVDEYQDSNLVQETIINMISKGDDASPGVFMVGDVKQSIYRFRQARPELFLEKYNTYLPDKGSPCRKIILSRNFRSRREVIDAVNFLFKQIMSTGAGELDYTDAEALNFGAVFDENAKEDITVGGEVEFHLIQTEDEDKNFTFENEGEEGRQADEGEEDEEMLDSIQCEARLVGRRILELMKPDENGRYFSVFDKAKNEYRRVEYRDVVILLRTTRNWAEVFVDELSVMGIPVFADTGTGFFKTVEVQVMLSLLQIIDNPLQDIPLLSVLRSPIVGFTTDELAELRLVDKKALLFDALKKLAESGQGEAAGKASAFLENLQKWREMSLYMSTDRLLWQLYNDTGYYSIVGAMPAGEQRQANLRILYERARQFEETSYKGLFNFINFIDKLKSSRGDMGSAKILSENDNVVRIMSIHKSKGLEFPVVIVAGCGKKFNLQDMNKSILLHHELGFGPDVVDHKLRLSWPSVAKQAIREKIKAETLSEEMRILYVALTRAREKLVITGAVKNVRKAVEKWLDSASVQKSRLSAYDMLSGANYLDWIGPALLRHKNCGGLRDCVGSAGFRGLLIDDPSVWSVKIWNKTDVQSSGVSEEQGESEFIKWLDSLEKEEPSEYAEETARRLSWSYPYVKASKVPAKVSVTELKRRYNEVVSEDVMQFPDYMPVLVKKPMFLEEKKGLTYAEKGTILHFVMQHLDYGREDIEAQIEEMVAKDLLTPQQAQSVDAARIRRFLNSPLGKRMLASKSINREVPFNIEIPCHELYRDMEDEACHGETLLLQGVVDCYFEEPDGIVLVDYKTDYVAPGNVETIRERYKVQILYYARALEMLTGKKVKEKYIYLFWDGRILGF
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: MDMV_MUSDO
Sequence: MNATDAESRKPENKPSSESSSSGSTSGSSDGEVSSKTYFKNNKSKVLSGQREVVLEVVRDLSYTICKEAEEKLVERFPRKDGSNEMLPKEDSINTNHNYTTDSNEHPVELTTKTEECKNTEKTKKKSFVRALSKDKQLSAYRSRSRSTRLSYSGHISRTHSVEKSLSRYKKSVLRSRRTSFGHGRDSSTTKRSVSRDKDNRLRRRIGSSRSHTRSHSRFRRSEKKLPSRSPRRIRSQERRHERRRSMSSDYERIALRRSEPIKRRDKDEFFKNNKKVSGDIKKGKGNDNGTVAELEAKITERQRKSLDILTSRTGGACLTPDKLRMIQAEITDKSSAAYQSIAREALKKYIHGYINKVNVDSVAVITRKLLKDNIVRGRGVLCHSIIQAQATSPTFTHVYAAMVAIINSKFPNIGELLLKRLVIQFKRAFGCNDKTVCLTSSHFIAHLVNQRVAHEILALEILTLLIESPTDDNVEVAITFLKECGMKLTEVSSDRVGGIFELLKNILHQGKLDKRVQYMIKVLFQVRRDGFKDHQSIIESLELVEEYAQFTHLLLLEDVTYPKDILNEFKFDDQYETNEEKYKALSKNILGSHASDSDGSFGSGSNSETALSDCDKGKNEVNDKYTSGDIIDETKPNLIALRRTIYLTLNSCLDYEECAQKLMKMQLKTCQQNEFCQILLDCCAEQRTYEKFYGLLTHRICKMNKSFIEPFKEIFKDICQTTHCLDTNRLRNISKFFAHLLFTDAISWDVLDCIKLTEDEAITSRCIFIKSFFQELVEYMGLYHFNKKLKTEVLAGTLAGLFPKDNPRNIRFSINFFTSIGLGGITNELCQLLKIAPKSAPSSSSSSSLSSELSAPSDDDSSSDSENKKKHKGKNKKMTKKKNPSKKKEKTKKIVGKNKIAAKNKTIKRRTDKDNSSSKDNFLKSESSSNESISLDSLSSELFAPSSYSSSESSNDSESKEKHKGKNKKMTKKKNPSNKREKTKKKLSKNKKAPNKNTKKRMTEKDISSSESSISESKSLNCSASNQNENEKRKKRVTSKSRTKRVKMFKQCQWVDADNQRDIKRKKRAEYRYEPLVYRKRNEECLKKGAPNCRKDNYGNRQNHEISQRHDSEIKRRREERKKRHHEKNHSREYKRSKLGLCQREYFLYMCCQFYYPCTFQCLCQNCHFTFYS
What is the function of this protein?
Male determiner protein (M-factor) that controls male somatic sexual differentiation.  Acts as a dominant factor that regulates the mRNA splicing of transformer (tra) and doublesex (dsx) transcripts and promotes expression of male splice forms of tra and dsx (By similarity).  Probably acts as a component of the spliceosome C complex required for mRNA splicing factor and exon-junction complex (EJC) assembly (By similarity).  Hinders eIF4AIII from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs (By similarity).
What are the official names of this protein?
Male determiner protein Mdmd(V), Male determiner encoded on chromosome V.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: DHC5B_DANRE
Sequence: MPVGLSVGGALGDPSPSRPFRPSRYVPVSAATAFLVGATTLFLCFTCPWLSEKFSSFIPLYNVVVFLFTLANFCMATFMDPGVFPRAEEDEDKEDDFRAPLYKTVEVRGIQVRMKWCSTCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTVHIMDVFGFSLLYILHHTKQLDLVQSGVTMAVMCVAGLFFVPVAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTHGCFKNIAHVLCSSQAPRYLGRLRKPQSVQVQPPFLRPPLSEAQLAAKVLDNGIQQSKSSLEIMESQSTDADPPPPPKPEHRYPGLPHTQNEECSLLTEAPPTPSLYKYRPAYSSPGKNHTASTHSSKMSRGNSMTESPSVPVTTGQPSYRSDPSLSSRGAAGCRGGAEGGRSGSGGLGGASAFGGRSYPSFTDTLLQSAAASCSSSLRSAHTAHNALGPLISEGTTSTSYKSLANQTRNGSLSYESLLTPSESPEFESAAHELSPPRPHPPHSLSTAAGAAPILGYTSPFLSAQQREGSLQACPAPLRPSPNRAFLRPISSPPSRAPPLSPRARSLGSPPPGPAPGHTPLGKSMSYGGGAELQHRPSSSGGGTSMPNSTIKQNVANHNTHSHKPARGVKKVSGVGGTTYEISV
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes.
What are the official names of this protein?
Palmitoyltransferase ZDHHC5-B, Zdhhc5-like, Zinc finger DHHC domain-containing protein 5-B, DHHC-5B.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM3_YERIN
Sequence: MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQVELVPMVTRGDIILDTPLAKVGGKGLFVKELELALLDGRADIAVHSMKDVPVAFPEGLGLVTICEPDDPRDAFVSPHFAHIDDLPAGSIVGNSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYHAIILAVAGLNRLGLASRI
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: TYSY_STRMU
Sequence: MSKADFIFKKNIKKILTDGVWSEQARPKYKNGKTANSKYITGAFAEYDLAKGEFPITTLRPIAIKSAIKEVFWIYQDQTNELAILNDKYGVRYWNDWEVKQTGTIGERYGAIVKKHDIMNKILKQLEENPWNRRNVISLWDYEAFEKTEGLLPCAFQIMFDVRRVKGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFVNNLHIYDNQFEQAEELLRREPVVCQPHLVLNVPNKTNFFDIKPEDFELLDYEPVKPQLKFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_CAMHC
Sequence: MYRFAPSPTGDMHIGNLRAAIFNYICSLQDKSGFILRIEDTDTARNISGKGEEIKEILKQFGIKWDKLYIQSENLKFHRELASKLLNDKKAFCCFCSEEELAAKKAAAKKAGVAYRYDGTCEKLSDLEVLNCEKPFVIRMKKPNRILKFNDLIKGEIGFEPENIDSFVIMRVDKTPTYNFACAVDDMLEGVTCVIRGEDHVSNTPKQNWIRECLGYTEEISYAHLPIILNEDGKKMSKRENSSSVKWLLQSGYLPEAIANYLILLGNKTPCEVFTLDEAVEWFDISKISKNPAKFDISKLAFLNREHIKRADSARLVEVFGLDESFSELIKFYTQEASLVGEIKEKIKSIFSKKEIPAEFAENVKILKDEILKIKELPENFENFKEILTKATNLKGKNFFMPLRILLTGANHGPELKELYPLLRSQIKRIVNL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH1_STAAT
Sequence: MNKFKGNKVVLIGNGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKAGEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPVDILAYATWKFSGLPKERVIGSGTILDSARFRLLLSEAFDVAPRSVDAQIIGEHGDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQTRDAAYDIIQAKGATYYGVAMGLARITEAIFRNEDAVLTVSALLEGEYEEEDVYIGVPAVINRNGIRNVVEIPLNDEEQSKFAHSAKTLKDIMAEAEELK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate (Potential).  Appears to be the primary factor that allows S. aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells (By similarity).
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 087L_FRG3G
Sequence: MYLNALAKVRRGGGGGRPAAGGRPAAGGRPAAGGRPAAGSRAAAGAAGPPKPAKTVRGTVRPRGFGGGRFPPRRFPPAPVDEATREAEKILKSIHAHKVVKLPAQRKKHRGLYKTVRHTMPPDYIPVLGAEVLAGISSPDVMQAVLRIAPTRDNTQAADAMLCATILRAMPYKMVHPFLDMAAEGKDRHANVVLRDTFFPQNARTMDEFKAFMRRRAPDCPSPRTPMVKPPFRIPDAKPGLTPSVRNPRLNIPETAMVSIMTSAPWVAGHSIKGTVLPEGSTGALRGGLASRRWYVDNWVSVRMMGNPPVEYLTFSGKRIPETREMYDAYVRHLQSFGATAVSSSPSPPPNGDAATALANMYVDTGPEYLAALVRALPSGSGAEYEAALAYTVARAVPVFSNGETLHQIRLREGRYRPDGVHGLSDDIAFAEVYSDPDMVAEWKPRLDRIIKARVSEVIAAYRRLATGDLTAKRTPELALSSRIPAPAGLLFPKAFGESAVIRTSRGRRLVIARARRDAPAVLTDLLSVLITPMYPATAEPQRVASDDPTVLGDEPVAAAVEEPRGQAFRRKWGRGVGGKLLDALENYMDAIQQGRLPPYDNDME
What are the official names of this protein?
Uncharacterized protein 087L.
Protein: ACCD1_LYSSC
Sequence: MAIRSLFRKKNEDGQEKGFPEGLMTKCPECRHILLTKELEKNHKVCTKCDHHFKMTAQERVAYFIDEGSFVSMDDHLQTSNPLNFPDYVEKISVAKQQTGLSEAVLTGVGTLDGEEIVVAIMDSHFRMGSMGSVVGEKITRAVEKAIELRVPVIIFTASGGARMQEGILSLMQMVKTSVALKRHSEEGLLFISIMTHPTYGGVSASFASVGDINIAEPQALIGFAGRRVIEETLREKLPNDFQKSEFLLAHGQLDAVFHRKDLRNQVAMLVKMHTKGGVQHV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 1, ACCase subunit beta 1, Acetyl-CoA carboxylase carboxyltransferase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP1_MAIZE
Sequence: MTDGHHFNNILLGGRGGTNPGQFKVHSGGLAWKRQGGGKTIEIDKADVTAVTWMKVPRAYQLGVRIKAGLFYRFIGFREQDVSNLTNFIQKNMGVTPDEKQLSVSGQNWGGIDIDGNMLTFMVGSKQAFEVSLPDVAQTQMQGKTDVLLELHVDDTTGANEKDSLMDLSFHVPTSNTQFVGDESRPPAHILWETILKFADVGSSEEPVVTFEGIAILTPRGRYSVELHLSFLRLQGQANDFKIQYSSIVRLFLLPKSNNPHTFVVITLDPPIRKGQTLYPHIVIQFETEAVVERDLALSKELLVEKYKDRLEESYKGLIHEVFTKVLRGLSGAKVTRPGSFRSCQDGYAVKSSLKAEDGLLYPLEKGFFFLPKPPTLILHEEIEFVEFERHGAGGASISSHYFDLLVKLKNDQEHLFRNIQRNEYHNLFNFINGKNIKIMNLGGDGQGASGVVTDVLRDTDDDAVDPHLERIKNQAGDEESDEEDEDFVADKDDSGSPTDDSGDEESDASDSGGEKEKSSKKEASSSKPVQKRKHKARDDEGQEKKKPKKKKDPNAPKRAMTPFMYFSMAERGNMKSSNPDLPTTEIAKKLGEMWQKMSGEEKQPYIQQAQVDKKRYEKESAVYRGEATVDVDSGNESD
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).  Binds specifically to double-stranded DNA.
What are the official names of this protein?
FACT complex subunit SSRP1, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Zm-SSRP1.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PKND_CHLFF
Sequence: MQRYDIIRMIGKGGMGEVYLAYDPVCSRKVALKRIREDLSDNELLKKRFLREAKIAADLVHPGVVPVFTICSDSDPVYYTMPYIEGYTLKSLLKSVWQCDSLPKDLAEQTSVGTFLSIFHKICSTVEYVHSRGILHRDLKPDNILLGLFSEVVILDWGAALSKEMQEEVLLDIDIPVTGSMFSNMTIPGKIVGTPDYMAPERLRGTPASESTDIYALGVILYQMLTLSFPYRNKKGKKISFRHQISSPEEIAPHREIPPFLSQVAMKALAADPKVRYASVKELKDDIEQHLQGSPEWTPKTILHTQKAECWKLRESILLSKYFPMLGVSPALWYSLAISKIESFSEVRLEYTLLRKGLEDGFGILLPPSEGVDHGDFYHGYGFWLHIKNSVFSVSLVKNGLEIRKTSRPIKENKEKFFIALEKQNHRLSLIIDHVVWMIHMDYLPGRGGRIGVIIQDVTDVCGNIVVLESSGSLQVSCLAVPDAFLNEKLYDRAITFYRRIAESFPGRKEGYEAQFRIGIALLEKASESGDSEGFTQALGKFEILHNSVAAPLEYLGKALVYQRLGEYNEEVKSLLLALKRYCQCPEISRIRDHIVYRLHETLYSNHRLSLVFMLLALHIAPESINATEEEYFVKNLHGKIQDTLFCNLDLSPIDFRSSKMELLLSYWSGFTPFLPGLFQKYWDLKDYRALADVFYVAADLGNREFLEMYSDLVRENICSTTCTEDIVEFLPHQLEHFFSGVRAISLHEPLEKVFAHIEILDPVLILYLFDLFAKDALIHHRGELILSAITLIEKYVSSQQYYEHLLPCEVLAYLWMKDEKKVYNLLCNNYEESLWLDDRSPAFVLYGCWLALVEDSSLSYLHLSGCREDALYPRALIGGFCSPLGICENQLSYQERRKLLLQKFIFFHCLGMNEERDNCTVAYDLLSIERSL
What is the function of this protein?
Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.
What are the official names of this protein?
Serine/threonine-protein kinase PknD.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: SEP2B_OSTSE
Sequence: IIGDEINGAITTADNIAGKIGII
What is the function of this protein?
May act as an antimicrobial peptide.
What are the official names of this protein?
Septenin 2b.
What is the protein family that this protein belongs to?
Belongs to the Frog skin active peptide (FSAP) family. Septenin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BP44_BPMU
Sequence: MSNTVTLRADGRLFTGWTSVSVTRSIESVAGYFELGVNVPPGTDLSGLAPGKKFTLEIGGQIVCTGYIDSRRRQMTADSMKITVAGRDKTADLIDCAAVYSGGQWKNRTLEQIARDLCAPYGVTVRWELSDKESSAAFPGFTLDHSETVYEALVRASRARGVLMTSNAAGELVFSRAASTATDELVLGENLLTLDFEEDFRDRFSEYTVKGYARANGAEGDDIDAKSIVSRKGTATDSDVTRYRPMIIIADSKITAKDAQARALREQRRRLAKSITFEAEIDGWTRKDGQLWMPNLLVTIDASKYAIKTTELLVSKVTLILNDQDGLKTRVSLAPREGFLVPVESDRKNRKGGDSNGGIDALVEDYYRRHPEKTPPWKE
What is the function of this protein?
Forms the central cylindrical hub of the baseplate and plays an important role in baseplate and tail assembly (Probable).  Core component of the initiator complex that triggers the tail tube polymerization during tail assembly (Probable).  Forms a conduit that probably functions as an extension of the tail tube allowing viral DNA release during ejection.  Might facilitate the interaction of the virus with the host cell surface through electrostatic interactions during virus entry into host cell.
What are the official names of this protein?
Baseplate hub protein gp44, 43 kDa tail protein, Gene product 44, gp44, Gene product P, gpP.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Baseplate protein.
Protein: DEFN_ARCDE
Sequence: DKLIGSCVWGAVNYTSNCNAECKRRGYKGGHCGSFANVNCWCET
What is the function of this protein?
Possesses potent anti-fungal activity.
What are the official names of this protein?
Defensin ARD1.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YEBW_ECOLI
Sequence: MFALVLFVCYLDGGCEDIVVDVYNTEQQCLYSMSDQRIRQGGCFPIEDFIDGFWRPAQEYGDF
What are the official names of this protein?
Uncharacterized protein YebW.