PharMolix/UniProtQA huggingface dataset:
Protein: PDXB_BLOFL
Sequence: MRILADQAIPYVYKLFGSDNYVQVCDGRSISANMLKDVDVLIIRSITKVNHMLLYDSSIKFIGTVTSGVDHIDQNYLKNNNIRCVSTPGSNAVSVVEYVCATLFWLAQRDCFFLRDKTVGIIGVGNIGNLLYQRLNSLGVHTLLYDPYKSKCDTDRMSWKSLDILVSKSDILTLHVPLTYTGAYPTWHMINKDILDALPSNSILINTSRGAVVNNDDLLAILRCGKKINVILDVWESEPKLSLPLLSYVDIGTAHIAGYSFESRIRSIKKIYDDYCDYFNVKNKVNWISLGLSDIRYIAVSRLDECIINRLIQLVYNVYYDHIALKNNVLRLRGFDKLREYYCFRREWSSLLVDSKNGYNNDILFKFGFSTL
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_PAVHU
Sequence: MELFRGVLQVSSNVLDCANDNWWCSLLDLDTSDWEPLTHTNRLMAIYLSSVASKLDFTGGPLAGCLYFFQVECNKFEEGYHIHVVTGGPGLNPRNLTVCVEGLFNNVLYHLVTENVKLKFLPGMTTKGKYFRDGEQFIENYLMKKIPLNVVWCVTNIDGYIDTCISATFRRGACHAKKPRITTAINDTSSDAGESSGTGAEVVPFNGKGTKASIKFQTMVNWLCENRVFTEDKWKLVDFNQYTLLSSSHSGSFQIQSALKLAIYKATNLVPTSTFLLHTDFEQVMCIKDNKIVKLLLCQNYDPLLVGQHVLKWIDKKCGKKNTLWFYGPPSTGKTNLAMAIAKSVPVYGMVNWNNENFPFNDVAGKSLVVWDEGIIKSTIVEAAKAILGGQPTRVDQKMRGSVAVPGVPVVITSNGDITFVVSGNTTTTVHAKALKERMVKLNFTVRCSPDMGLLTEADVQQWLTWCNAQSWDHYENWAINYTFDFPGINADALHPDLQTTPIVTDTSISSSGGESSEELSESSFFNLITPGAWNTETPRSSTPIPGTSSGESFVGSPVSSEVVAASWEEAFYTPLADQFRELLVGVDYVWDGVRGLPVCCVQHINNSGGGLGLCPHCINVGAWYNGWKFREFTPDLVRCSCHVGASNPFSVLTCKKCAYLSGLQSFVDYE
What is the function of this protein?
Multifunctional protein essential for viral DNA replication, which cooperatively interacts with the viral DNA origin of replication and transactivates several promoters including the viral p6 promoter.  Binds the origin of replication and performs an endonucleolytic nick within a conserved sequence in the viral genome, thereby initiating the rolling circle replication (RCR).  Participates in the transcriptional regulation the viral p6 promoter that regulates all viral transcripts and the cellular CDN1A or IL6 promoters.  Transactivates several host promoters some of which induce the S cell cycle phase for the production of host replicative proteins.  Up-regulates the expression of host E2F4 and E2F5 and interacts with both these factors thereby inhibiting the host cell cycle G2/M transition.  This arrest promotes apoptosis for viral release.
What are the official names of this protein?
Initiator protein NS1, NS1, NCVP1, Non-capsid protein NS-1, Non-structural protein 1, Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the parvoviruses initiator protein NS1 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: VRAC_STAAM
Sequence: MQHYLLDSNQRLNVSFSKDSVAAYYQCFNQPYRKEVPPLMCASLWPKFDLFKKYANSELILTKSAINQTQKIEVDTIYVGHLEDIECRQTRNITRYTMALTLTKNDQHVITVTQTFIKAMK
What are the official names of this protein?
Protein VraC.
Protein: HD8_ENCCU
Sequence: MRKNDFDVREMNAALGILKLAREGRGDSDEPDTRTRKTTFQMMVLKEVFKIAPHPSTLTKADLALMIKLPLKAVQIWFQNERSRKERGGRLGKRTRGGKSESIDPVRLFKVIMKVLEKNREGLGF
What are the official names of this protein?
Homeobox protein HD-8, EcHD-8.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOC2B_DICDI
Sequence: MSKESRIFIEISENIIDLNYWYKIVSDDSSGATSSFLGTTRNEFKGKSVERLEYETYEPMAIKEIEKICKTILNGFENDIKKIGIVHRIGNVPVGESSILIVISSGHRKSSLEAVHYAIDTIKSTVPIWKKEFYTDGSENQWKGNCESCHFNNNNHPH
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated mocs2s into precursor Z to generate a dithiolene group (By similarity).
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, MOCO1-B, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B, Molybdopterin synthase large subunit, MPT synthase large subunit.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_PHOPR
Sequence: MKRIFQTIALIGKPRNPDALQTHKTLFDWLTGKGYDVLVDHRLANDLDVPQDCLCDLLTIGDKANLAIVVGGDGNMLGAARVLSRFDIAVIGVNRGNLGFLTDLDPESFKEELTRVLEGEFVTERRFLLEAEVHRHGQIKSRNAALNEAVLHPDKIAHMIEFEVYIDDNFAFSQRSDGLIIATPTGSTAYSLSGGGPILSPSLNAITLVPMFPHTLSSRPLVVDGDRCIKLLVSPNNGSTLEVSCDGQVSLPVSPGDEVHIYQSPEQLQLIHPKNYNYYGVLRAKLGWSSKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLQD_BACSU
Sequence: MQIIHRVAVMQVLTERSKEKLLASFAEKKQMLERECSQLYFQLRKHEKEQQNPNMIEQFKKAIEKRKDDIKIIDFQIAQVHTLPLGSELKEKEVDALLTIEAGDDWHEKTAANTIVIKDGKVIEIRQR
What are the official names of this protein?
Uncharacterized protein YlqD.
Protein: NADA_ECOL5
Sequence: MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGCYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVEMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALELEGSNHEVYVDERLLERALVPLNRMLDFAATLRG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_CALS4
Sequence: MLKKDLLGIKDLTREEILEILDLAFEMKKLLNGEKYSQALRGKTVVTIFFEPSTRTRLSFEMAAKYLGAHYGNIEVATSSVVKGESLIDTIRTVERMKADVIVTRHNMSGTPHLLAKYTNASIINGGDGINEHPTQALLDMMTIKEKKGDFKGLKVAIIGDIMHSRVARSNIWGLKKLGAEVKVAGPSTLMPPQIEKMGVKVCYNAEEAIKDADVVMGLRIQLERQKSGLFPSIEEYREYFGINEERMRLAKSDAILMHPGPINRNVEVTSGAANASYSVIEEQITNGVAVRMALLKILCERRN
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TXG1A_SCOAL
Sequence: MAPPSNPLFVVLCWALFAYLMLVLRDIQAAERQYRTESRDGKCVGEDGLLHAPTELWYNDNDCSEHTCVNDNTGYYEIIRRCTLIVYPPECHLMNGTGTRYPKCCCKVTCELN
What are the official names of this protein?
U-scoloptoxin(16)-Sa1a, U-SLPTX(16)-Sa1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_STRPD
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVADAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: Y3827_MYCTA
Sequence: MARTDDDSWDLATGVGATATLVAAGRARAARAAQPLIDDPFAEPLVRAVGVEFLTRWATGELDAADVDDPDAAWGLQRMTTELVVRTRYFDQFFLDAAAAGVRQAVILASGLDARGYRLPWPADTTVFEVDQPRVLEFKAQTLAGLGAQPTADLRMVPADLRHDWPDALRRGGFDAAEPAAWIAEGLFGYLPPDAQNRLLDHVTDLSAPGSRLALEAFLGSADRDSARVEEMIRTATRGWREHGFHLDIWALNYAGPRHEVSGYLDNHGWRSVGTTTAQLLAAHDLPAAPALPAGLADRPNYWTCVLG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MRA_3827.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: PYRR_STRP1
Sequence: MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVFLARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYTGRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVEVDGRDRVSIIDST
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: UREF2_BRUAB
Sequence: MTMRTATITEFSSSYRSLPGLLHLLQFGDSALPIGGFSFSNGLESAIQQNLVHDKETLREFTLTAMNQAATSDGIALLTAHRAARADDRGALQVIDKAVFERKLNEETRLMTVRMGRKLCELSASIIDDRLNRDWLECIKTAETPGTHPVSLGLAFAALDVDGRDAFGAQQYGVATTILGAALRLMRVSFMDTQKILLEATSTVAPAYEEIADAGIEDMASFAPMVDILAAVHVKGHVRMFMN
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF 2.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_CUPNH
Sequence: MNAVAEAPVTEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFDEEVNEDDTTMVKNGVTLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: SELO_ECO81
Sequence: MTLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIPSSLFKNGAGVWGGETLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETVESGAMLMRVAPSHLRFGHFEHFYYRREPEKVRQLADFAIRHYWSHLDDEEDKYRLWFTDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDGLNEALDSYQQVLLTHYGQRMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRVRLQQDEVTDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: PAX_I43A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKSQEQCASSPTKVSRRTSPALKILEPMWMDSSRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: ERPA_SHIF8
Sequence: MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: METN_XANOM
Sequence: MIEFQRLHKSYSVDGRQIVALHPLDLRIGPGEVFGIIGHSGAGKSTLIRLINRLEEPSGGRLLIGDEDVTALDSQGLRALRRRIGMIFQHFNLLSSRTVAGNVAFPLELVGTPRAEIDARVAELLARVGLQEQANQYPAQLSGGQKQRVGIARALATGPQILLCDEATSALDPQTTASVLQLLAQINRELGLTIVLITHEMDVIRRVCDRVAVLDAGKLVETGPVTEVFLHPKHVTTRRFVSEAEHLDEAELHRDFAAVGGRIVRLTFLGNGTYEPVLGRIARDTGVDYNILSGRVDRIKDTPYGQLIVALTGGDQTAARAGFVAAGVQVEDLRV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FABZ_BURL3
Sequence: MSTEKINLDIHKILTLLPHRYPILLVDRVLELEPHKGIKALKNVSINEPYFQGHFPKRPVMPGVLILEALAQAAALLTFSEEQPKDPENTLYYFVGIDGARFKRPVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTTDVAP
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_BUCAT
Sequence: MSLCLWKQCLDRLQDELPNTEFSMWIRSLKAKLNNNILEIYAPNKFVLEWVKDKYLNHLKKILQDYCGTNSPLIKFEIYQIYKENKLKKNIENNNNNKNEKLIWSNIPKFKNLSYRSNINKRYNFQNFVEGKSNQLARSAAFQAARNPGNSYNPLFLYGATGLGKTHLLHAIGNEILSYKYDIKIIFMNSECFVQDMVKALKNNAIEKFKLYYRSVDALLIDDIQFFAHKERSQEEFFHTFNTLIEGNQQIILTSDRYPKEINGVEDRLKSRFSWGLTIAIDPPEIETRVAILIKKADQNNVILSNEVAFFIAKHLRSNVRELEGALNRVILNSRFTHRAITVDFAREALQDILAVQEKIITIDNIQKTVAKYYKIKVSDLLSKKRSRSIARPRQMAMAMAKKLTNHSLPEIGEAFSGRDHTTVLHACCKIEQLRKENHDIKKDFLNLIRTLSK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_CLOB1
Sequence: MKYSAGDFDVVVIGAGHAGCEAALASARMGCKTLICTMNLDSIALMACNPNIGGTAKGHLVREIDALGGEMGINIDHTFIQSRMLNTSKGPAVHSLRAQADKKRYSERMKHLLEKEDNVVLRQLEVIEIDVEDNEVKGVLTKNGAYFTTKAIILCTGTYLKGKIIIGDIIYSSGPSGLYPANDLSQSLLDLGINLRRFKTGTPARINKRSVDFSKMIEQPGDEKIVPFSFIHNKLDKDQISCYLTYTSEETHKIIHENIHRSPLYNGSIEGVGPRYCPSIEDKIVRFPDKDKHQIFIEPEGENTEELYVGGMSSSLPEDVQIKMYRSVPGLENAEILRTAYAIEYDCIDPQQLDLTLEFKNINGLYGAGQFNGSSGYEEAAAQGLIAGINAVLKIKEKNPLILKRSDAYIGVLIDDLVTKGTNEPYRMMTSRAEYRLLLRQDNADLRLTELGYKVGLVKEDRYNKFLNRKKNVENEIERLRNMQITGKREINEFLLEKGSTELKKPISLYELIKRPELDYFKVESLDDKRPSLSDDEKEEINIIAKYEGYINKQLEQVEQFKKYEDRLIPKSINYLDIKGLRLEAIQKLEKIKPINIGQASRISGVSPADISVLLIYMERKNREN
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAS_ECOSE
Sequence: MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAQTLAQEFFRDVEAGLDPDVPYNYFPHNDPQNTPRASWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNT1_RAT
Sequence: MGCWGRNRGRLLCMLLLTFMFMVLEVVVSRVTASLAMLSDSFHMLSDVLALVVALVAERFARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAVERFIEPHEMQQPLVVLSVGVAGLLVNVLGLCLFHHHSGEGQGAGHGHSHGHGHGHLAKGARKAGRAGGEAGAPPGRAPDQEPDQEETNTLVANTSNSNGLKADQAEPEKLRSDDPVDVQVNGNLIQESDSLESEDNRAGQLNMRGVFLHVLGDALGSVIVVVNALVFYFSWKGCTEDDFCVNPCFPDPCKSSVELMNSTQAPMHEAGPCWVLYLDPTLCIIMVCILLYTTYPLLKESALILLQTVPKQIDIKHLVKELRDVEGVEEVHELHVWQLAGSRIIATAHIKCEDPASYMQVAKTIKDVFHNHGIHATTIQPEFASVGSKSSVVPCELACRTQCALKQCCGTRPQVHSGKEAEKAPTVSISCLELSENLEKKPRRTKAEGSVPAVVIEIKNVPNKQPESSL
What is the function of this protein?
Zinc ion:proton antiporter that could function at the plasma membrane mediating zinc efflux from cells against its electrochemical gradient protecting them from intracellular zinc accumulation and toxicity (PubMed:7882967, PubMed:19095042, PubMed:24951051).  Alternatively, could prevent the transport to the plasma membrane of CACNB2, the L-type calcium channels regulatory subunit, through a yet to be defined mechanism.  By modulating the expression of these channels at the plasma membrane, could prevent calcium and zinc influx into cells.  By the same mechanism, could also prevent L-type calcium channels-mediated heavy metal influx into cells (PubMed:15378655, PubMed:16741752, PubMed:19767393).  In some cells, could also function as a zinc ion:proton antiporter mediating zinc entry into the lumen of cytoplasmic vesicles.  In macrophages, can increase zinc ions concentration into the lumen of cytoplasmic vesicles containing engulfed bacteria and could help inactivate them (By similarity).
What are the official names of this protein?
Proton-coupled zinc antiporter SLC30A1, Solute carrier family 30 member 1, Zinc transporter 1, ZnT-1.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localized on the basolateral surface of the enterocytes.
Protein: PANC_AGRRK
Sequence: METISTIAALRERLAAYRRAGKSIGLVPTMGYLHAGHMELVSRARAENDIVVVSIFVNPLQFGANEDLAKYPRDLERDSAILRDGKVDFIFAPGVADMYPRPMETVVDVPKLGTELEGAVRPGHFAGVATVVTKLFNIVQPDSAYFGEKDYQQVAIIRRMVEDLAQPVRVVPVPTVRDADGLALSSRNVYLSTEQRAAAVIVPKALAEAERLYNEGADDPIAFEAALRDFIASEPFATPEVTAVRHPDTLEPLTNLQGQPILVALFVRIGATRLLDNRVVGRKQASSDKAA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KKX41_HETPE
Sequence: MKSTLMTASLLILVVLFIIDYASVYAEFIDGEISLERERDIPCFETCMKLYHIPKLCYIKCRKH
What is the function of this protein?
Potassium channel inhibitor (Kv).
What are the official names of this protein?
Potassium channel toxin kappa-KTx 4.1, HSP040C.2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor kappa-KTx family. Kappa-KTx 4 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HUTI_CHLAD
Sequence: MEPCDLLIHSATQLVTCAGPPGLRRGPAMRELGVIRDGAVAIRGSTIVAVGPGTDVRRRFRASHEIDARGRAVCPGLVDCHTHIVYAGDRVEEFEQRCAGATYQEIMAAGGGILRTMRLTRAATTTELVHAALPRLRQMLSFGTTTAEVKTGYGLERDAELRQLAAIALLDAAQPIELVPTFLAAHAVPPEFTGRADDYIDLVVESMLPLARDWYAVSSFAARAIPLFVDVFCERGAFDVAQSRRVLDAARSLGLPRKAHVDEFVELGGLAMALELGATSVDHLDVTGPSAFTALAASSTVAVLLPLVSLNLGLSHFAAARAMIDAGVAVALSTDANPGSAPSLSLPLTMAIACRYLRMLPAETLIATTVNAAYAIGRGGHVGALMPGMQADLLILAADDYRWLMYELGGMPVAQVIKRGQVVVTNE
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_HERAR
Sequence: MALLQIAEPGMSTAPHQHRLAVGIDLGTTNSLVATVRNSIPEILTDEEGRSLLPSVVHYLKNGSAHIGYKAQAAQNTDPKNTIVSVKRFMGRGLKDIAYAENLPYDFLDTPGMVQLKTVAGVKSPVEVSAEILATLRQQAEDALGDDLVGAVITVPAYFDDAQRQATKDAAKLAGLNVLRLLNEPTAAAIAYGLDNGSEGVFAVYDLGGGTFDVSILKLTKGVFEVLSTGGDSALGGDDFDHRLFCWIIEQAGLAPLSEIDTSVLMVKAREAKELLSSKSETLIDAVLTSGEEVHVTVTAADFIQMTQHLVTKTITPTKKALRDAGLSVDDVDGVVMVGGATRMPHIRKAVGDFFQSTPLANIDPDKVVALGAAVQANLLAGNRAAGDDWLLLDVIPLSLGIETMGGLVEKVIPRNSTIPCARAQEFTTFKDGQTALAVHIVQGERELVTDCRSLAKFELRGIPPMAAGAARIRVTYQVDADGLLSVSARELRSGVEASISVKPSYGLADDQIAQMLQDSFKSADVDMAARALREEQVEAERIVLATQSALDADASLLSDNEREDIVALLDSVRQAGSGTDHLAIKAAVDALAHGTEEFAARRMDRSVRSALSGKKLDEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YM16_PARTE
Sequence: MLFWKVVTWDTLVFLPLYETSPIWLMSHCKAFFAFEMSSRVSEVSTYFASNEFFVLHEIFSKASYFFLVFELFFSNLMDAFLNNIVVFFEFDEPTLRRYISFMDPTLFSIYHPEAVFIQKSLLTTNHLSYFANFKLNVAVLLDKSNAIEPLNYMLQVSFLLYFIVSFQFFFFLSFLKTTRSTKSMLSTL
What are the official names of this protein?
Uncharacterized mitochondrial protein ORF16.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: THIE_NEIG1
Sequence: MTFPPLKSLLKFYAVVPTADWVGRMVKAGADTVQLRCKTLHGNELKREIARCVAACQGSRTQLFINDHWREAIEAGAYGVHLGQEDMDTADLAAIAAAGLRLGLSTHSVAELDRALFVHPGYIASGAIFQTTTKQMPTAPQGLDKLREYVEQARGTPVVAIGGIDLNNARAVLATGVSSLAAVRAVTEAANPEAVVKAFQALWDG
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RBL1_CERS5
Sequence: MDTKNTEIKGKERYKAGVLKYAQMGYWDGDYQPKDTDVLALFRITPQEGVDPIEAAAAVAGESSTATWTVVWTDRLTACDSYRAKAYKVEPVPGTPGQYFCYVAYDLILFEEGSIANLTASIIGNVFSFKPLKAARLEDMRFPVAYVKTYKGPPTGIIVERERLDKFGKPLLGATTKPKLGLSGKNYGRVVYEGLKGGLDFMKDDENINSQPFMHWRDRFLYVMEAVNLASAQTGEVKGHYLNITAGTMEEMYRRAEFAKSLGSVIVMVDLIIGYTAIQSISEWCRQNDMILHMHRAGHGTYTRQKNHGISFRVIAKWLRLAGVDHLHCGTAVGKLEGDPPTVQGYYNVCREPFNTVDLQRGLFFEQDWADLKKVMPVASGGIHAGQMHQLLSLFGDDVVLQFGGGTIGHPMGIQAGATANRVALEAMVLARNEGRNIDVEGPEILRAAAKWCKPLEAALDTWGNITFNYTSTDTSDFVPTPSVSM
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain 1, RuBisCO large subunit 1.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: Y2201_CHRSD
Sequence: MSNSNNDSRRRGLEMERRAADWLASHGLRLVDANQHARRGEIDLIMRDGDTLVFIEVRHRRDARHGHPFETVTAAKQRRLIGAARFYLHRNGLSCACRFDVVGVTGTPPHLSFEWIRSAFDAF
What are the official names of this protein?
UPF0102 protein Csal_2201.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.