PharMolix/UniProtQA huggingface dataset:
Protein: OTC_GEOMG
Sequence: MTRHFLALNQYTKEALDALFALTRELKEEQKKGIPHRILEGKSVALIFEKSSTRTRISFEVGVHQLGAHPLFISSATSQMGRGEPVRDTARVMARYCDGVMIRTYGQEIVEEFARYSSVPVINGLTDLFHPCQIMADLFTVIEHKGKYDGLKFAWVGDGNNMANTWIEAAAILGFDLALACPEGYEPDRTVWDWAQKKATSSITITRDPKEAVRDADVVNTDVWASMGQEQEQKVREVAFKGYCLDDDLVALAKPDCMVLHCLPAHRGEEITDSVIEGPRSAVWDEAENRLHVQKAIMASLLK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_FRATT
Sequence: MNLDFIKSKIAAVPDFPKPGIMFRDITPLLADPQGLRKTAEAMAQELKNKGIQPTIVAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRATYSVKYDLEYGSDSLEIHQDAFKVTDEVLVVDDLLATGGTAKATVDLIEKTQAKVAGLIFVMELDGLGGREVLAGYNVSALIKF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_CLOPE
Sequence: MAVKIRLRRMGAHKAPFYRVVVADSRSPRDGRFIEEIGYYNPIAKPEAEVKIDAEKAAKWLGNGAQPTDIVKKLFNQAGIK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y2474_ARATH
Sequence: MSPIENSSSWTLESDLEDLDLDLQDYKPSVPLKKVPNGDIFEASRAGDVDRLRYLVETGVNVNARDRWDSVALYYACLAGHIDSARLLLENGAICSEHTFDGDRCHYASLNLRIRKLLKAFEARPPPLAPLQASLRDTFLGCCHNRDYLQQEEANLDVSDTLSEFGSSNYFPPDVMFYVQGRPIEAHRVILSARSPFFKQKFENEWKDRREVRFSKEKLSYPALCSLIHFFYSDRLEISVDDMEDLVRICKVCKCESLQKIIEKELIHQRYAEYKTHRDLDNSMKRFILQGISLPEEDRLPASLHRILRVSLAKSFVGDVIDSSVGDTRVGDSVESLADVCVRVDKRNFYCHQVILASRSEYFRARLSRVNDFHEGKNGLPGDTLPFLEEHDLSAEAFEKMIEYMYTDGLKEINPNQAEEIFDVASRYLLFPLKRAVADALLPHLETATPAELCQWLVLSDMYGVLKIREYCLDLVACNFEAFVETHEFRAMLLTLPPPSGDSSLRTTVPSAPGAMMTTDQGNLLDDLREKWLEAEALELDMRDESALIFDKRLAMLVEIAEREKSESEAEDYKDTSA
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At2g04740.
Protein: RL35_DESDA
Sequence: MPKIKTRRSAAKRFSQTGSGKFKRRRQNLRHILTKKAASRKMRLGQSTTVDKANEKAVRRMLPNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RS16_RHOP2
Sequence: MSVVIRLARAGTKKRPFYHVVVADSRFPRDGRFIERLGYFNPLMAKDNEARLKLDLDKVKDWLAKGAQPSDRVARFLDITGVKKREARNNPEKAVPRKERKAAAEAAAKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ZUPT_SALTI
Sequence: MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLMEMLPAALDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQKRQQPLPGSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMAEILGGVLAWLILGSLVSPIVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSIMGLSLVILQTIGIG
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL32_COXB2
Sequence: MAVQKSRKTRSRRGMRRSHDALRGAMLSKDPTTGETHLRHHISPEGYYKGRQILTPKESYEDEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: PHNC_YERPE
Sequence: MGQALRKLTAADYPVVVQEPRKKVLAVKGLVKAYKSQHRVLDNINFELHAGEFVAIIGRSGAGKSTLLHILNGTIPTSAGEIINYHENGDTQNIAALTTKQMRKWRAKCGMIFQDFCLVPRLDVITNVLLGRLSYTSTLKSFFKLFSEQDQARAIELLQWLNMLPHALQRAENLSGGQMQRVAICRAMMQNPKILLADEPVASLDPKNTTRIMNTLQKISENDIAVIVNLHSVDLVKDYCTRVIGIAHGRIIFDGPPSMLNDSIIQDIYSDESAELLH
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS7_SYNP6
Sequence: MSRRTSAQKRSVNPDPKFNSRLASMMVARLMDSGKKSLAFRILYSAFDLIQERTGNDPLELFEQAVRNATPLVEVRARRVGGATYQVPMEVRSERGTAMALRWLVQYSRQRPGKSMAIKLANELMDAANETGSSVRKREETHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CXD3_MOUSE
Sequence: MGEWAFLGSLLDAVQLQSPLVGRLWLVIMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVIYSMHQASKEAGGAQLAPPCARGRAEAPCSPCALRARRARRCYLLSVALRLLAELAFLGGQALLYGFRVDPHYACAGPPCPHTVDCFVSRPTEKTVFVVFYFAVGLLSALLSVAELGHLLWKGRQRAKLLPPPPPSPSLPSQRGDPDPFGPPAYAHRSPAGDSEGEGGSGHSKASLATVRQDLAI
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction delta-3 protein, Connexin-30.2, Cx30.2, Gap junction alpha-11 protein, Gap junction chi-1 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Delta-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: MIAA_LATSS
Sequence: MKKEKIIVIVGPTGVGKTALSLQVAQQLKGEIISGDAMQVYRHLDIGTAKVTPAEQAIAPHHLIDVADIDERFTAFNFQQQGQQLITKITDRQHLPLIVGGTGLYLQALLYDMTLGSATDAEQDFSIRNKWQAYLEQHSETDLWQALAKIDPDAAAKIPAANTRRVIRALEVYETTGVLFSQQKPKELRYDTFIIGLNCERPVLYERINQRVDQMVDAGLIEEARWAYERRATSPQAVRGIGYKEFFPYFDGECSLEAAIDQVKQNSRHYAKRQLTWFRNQIPVNWYNLVEHQEADLARIQEDIQTWLQK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: VG51_EHV2
Sequence: MAKRINFTSCLIFTSCFTAFIVSLCLLVSSCVNLVNDVIIPSVHMSRRADITPFIDNYTINFTDLHFFTDGANASVPQPEAIFINSNNFSLYAHNCSARDNCSVHSASITQEGRCYHYSRAKYSFAGCLEFCRSYSPCYYLINPQKHMTAVRQNINESDTYWVGIFKSPKNTWVDLDNSSVTGVHDLYEDSYCAYIGLYTEVPWPSFYCDTPRRCLCGGSKGI
What are the official names of this protein?
Putative C-type lectin protein 51.
Protein: EXP24_ORYSJ
Sequence: MADMAPARALALVLLAVAVGSALMAAAQDAPSPPTPMAPSPSTDETPPVWLKAHATFYGGADASGTMGGACGYVDLYSQGYGTRNAALSTALFNDGASCGQCYKIACDRKRAPQWCKPGVTVTVTATNFCPPNWNLPSDNGGWCNPPRPHFDMAQPAWEKIGIYRAGIIPVMYQRVPCVKKGGVRFTINGHDYFNLVLVTNVATTGSIKSMDIMGSNSTDWMPMVRNWGANWHSLSYLTGQMLSFRVTNMDGQTLVFRNIVPSGWKFGQTFASKLQFK
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-A24, Alpha-expansin-24, OsEXP24, OsEXPA24, OsaEXPa1.10.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: TRHO_MARMS
Sequence: MSKVVVCALYKFVELPHFESLREPLQKTLEDNGIRGTLLLASEGINGTVAGSREGIDAMLAWLDQQPGLDKIVSKESYDEDMPFYRTKVKLKKEIVTMGVEGIDPKRVVGTYVKPSEWNALISDPDVVLVDTRNDYEVQIGTFKNAVNPKTDTFREFPAYVKENMDPAKHKKVAMFCTGGIRCEKSTAYMLEQGFEEVYHLEGGILKYLEEVPKEETLWEGECFVFDNRVSVNHDLQKGEYDQCHACRMPITEEEKQSEHYIQGVSCVHCVDKFTDEQRQRFIERERQVQLARSRGEEHIGAEVLSAVEKHRLEKALEKERQRKVREAKAN
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ZN615_PONAB
Sequence: MQAQESLTLEDVAVDFTWEEWQFLSPAQKDLYRDVMLENYSNLVAVGFQASKQDALSKLERGEETCTTEDEIYSRICFEIRKIDDPLQHHLQNRSIQKSVKQCHEQNMFGNIVNQNKGHFLLKQDRDTFDLHEKPLKSILSFENQKRSSGLKNSAEFNGDGKSLFHANHKQFYTEMKFPATAKPINKSQFIKQQRTHNIENAHVCSECGKAFLKLSQFIDHQRVHNGEKPHVCSMCGKAFSRKSRLMDHQRTHTELKHYECTECDKTFLKKSQLNIHQKTHMGEKPYTCSECGKAFIKKCRLIYHQRTHTGEKPHGCSVCGKAFSTKFSLTTHQKTHTGEKPYICSECGKGFIEKRRLIAHHRTHTGEKPFICNKCGKGFTLKNSLITHQQTHTEEKLYTCSECGKGFSMKHCLMVHQRTHTGEKPYKCNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLIVHQRTHTAEKPYICNDCGKGFTVKSRLIVHQRTHTGEKPYVCGECGKGFPAKIRLMGHQRTHTGEKPYICDECGKGFTEKSHLNVHRRTHTGEKPYVCSECGKGLTGKSMLIAHQRTHTGEKPYICNECGKGFTMKSTLSIHQQTHTGEKPYKCNECDKSFRKKTCLIQHQRFHTGKTSFACTECGKFSLRKNDLITHQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHLSILVKHKRIHR
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 615.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISK12_MOUSE
Sequence: MKPAGAFLLLISLACLFLSVDAVSQGGFQAFCSNYEKTLAPDGKSCPKTHKPVCGTDGKTYQNRCAFCQTAMERSLGKLGFKHEGKC
What is the function of this protein?
Inhibits trypsin.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 12.
What are the subcellular locations of this protein?
Secreted.
Protein: I5P2_CAEEL
Sequence: MDWKITIFTYNLAMKASDSEAVHNMLNGMIDDHTHLVAIGLQEVAHSETIGGAVLTWATTIASWMNTNGRMVLLAKTFQATNQVLIFGRKQLIGQIKRIDYRFQRNTMGGLTGHKGSIGVRLQLASPYSIVFVDSHFIHGPENYGKRVEQYHTNRNCSFPEDKSVRAAFWFGDFNFRVEEDVNTVIRKIKNGTHLELLDTREQLKRALVERDAFIGFHEQPVTFEPTYRVTVGTTEQDGKRVPSWTDRILYKGDGITGLSYTNNKKAVASDHLPVVAMFRVTAPAAPKPQWEVIFEHLPTWYTSIPLVGRFQVNELYYKENGSYRDWIGVFPSSINDCTTATNWIYAATCFEQVIEGSKFLACEFNNIPAGNYRLGYFSCHLHCLVGLSKVFQIVEQP
What is the function of this protein?
Dephosphorylates a number of phosphatidylinositols.  Controls the cellular levels and subcellular distribution of phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate.  Has a role in sperm activation and motility.  Influences the localization of the transient receptor potential polycystin (TRPP) complex proteins lov-1 and pkd-2.
What are the official names of this protein?
Inositol polyphosphate 5-phosphatase, Ciliary localization protein 1.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Observed in reticular structures.
Protein: RHLB_PROMH
Sequence: MSKTYLTEKKFSDFALHPKVIEALEKKGFSNCTQIQALTLPITVKGHDIAGQAQTGTGKTLAFLTSTFHYLLTHPAKEGHEKNQPRALIMAPTRELAVQIYTDAQPLAQSTGVKMGLAYGGDGYDEQLKVLNNGVDIVIGTTGRLIDYVKQGHINLNAIQVVVLDEADRMYDLGFIKDIRWLFRRMPNAAERMNMLFSATLSYRVRELAFEQMNNPEYVEVEPEQKTGFSIKEELFYPSNEEKMRLLQTLIEEEWPERCIIFANTKHRCDDIWAHLAADGHRVGLLTGDVPQKKRLRILEDFTQGNIDILVATDVAARGLHIPSVTHVFNYDLPDDCEDYVHRIGRTGRAGKSGNSISLACEEYALNLPAIETYIQHAIPVSKYNSDALLTDLPEPKRRHRPRQGQPRRNNSAPRRGNNTQRNNRNKRPSHS
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCXE_MESEU
Sequence: ARDAYIADDRNCVYTCALNPYCDSECKKNGADGSYCQWLGRFGNACWCKNLPDDVPIRKIPGEECR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission (By similarity).  Has paralytic activity in mice.
What are the official names of this protein?
Toxin BeM14, Neurotoxin M14.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH10_METBF
Sequence: MIIKPIGERVLLKHQKKQEVTKGGIYIPESARQEKKEGIVISVGTFEDGKELPLKKGDHVIYGGYQSDEIEIDDEKYIFVDFKDILATIAEE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_PIG
Sequence: MVFPSPLQGVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGREGKTAVVVGTITDDVRVQEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALDSPKGCGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN
What is the function of this protein?
Component of the large ribosomal subunit.
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (PubMed:24930395).
Protein: Y1769_BRUMB
Sequence: MAGHSQFKNIMHRKGRQDAVRSKMFSKLAREITVAAKQGLPDPAMNPRLRLAIQNAKAQSMPKDNIERAIKKAAGNDGENYDEVRYEGRGPGGVSVIVEALTDNRNRTASNVRAAFTKSGGSLGETGSVSFMFDRVGEIVYKPEAGDADKVMEAAIEAGAEDVQSGEDGHVILCAFEDIGEVSKALEAALGEAESIKTIWKPQTNTELDEEKARSVLKLLSVLEDDDDVQNVYTNFEVSDEVMEKLSA
What are the official names of this protein?
Probable transcriptional regulatory protein BMEA_A1769.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_PHAAN
Sequence: MKINASVRKICEKCRLIRRRGRIIVICFNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ABCF1_MOUSE
Sequence: MPKGPKQQPPEPEWIGDGEGTSPADKVVKKGKKDKKTKKTFFEELAVEDKQAGEEEKLQKEKEQQQQQQQQKKKRDTRKGRRKKDVDDDSDERVLMERLKQLSVPASDEEDEVPAPIPRGRKKAKGGNVFEALIQDDSEEEEEEEENRVLKPAKPEKNRINKAVAEEPPGLRSKKGKEEKSKGKAKSKPAAADSEGEEEEEDTAKEKEPPQQGKDRDKKEAEQGSGEEKEEKEGDLKANDPYANLSKKEKKKLKKQMDYERQVESLKAANAAENDFSVSQAEVSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLRLLEEERRLQGQLEQGDDTAAEKLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEVLTRKQQKCRRKNQDEESQEPPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQYAEQLHMEETPTEYLQRSFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINDYKGAVIVVSHDARLITETNCQLWVVEEQGVSQIDGDFDDYKREVLEALGEVMVNRPRD
What is the function of this protein?
Required for efficient Cap- and IRES-mediated mRNA translation initiation.  Not involved in the ribosome biogenesis (By similarity).
What are the official names of this protein?
ATP-binding cassette sub-family F member 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
Protein: MACB_VIBPA
Sequence: MSDVLLKVEDLTRRFVSGDESLTVLNHINLEIKRGEMVAIVGASGSGKSTLMNVLGCLDKPSSGRYFINGQDVSTLESDQLAELRREYFGFIFQRYHLLGDLTAVANVEVPAVYAGVPHRQRTERAQSLLARLGLEDRLTHKPSQLSGGQQQRVSVARALMNGGEVILADEPTGALDSHSGQEMMALLKELHQLGHTIILVTHDMNVANFADRIIEIKDGEIIADTLNAQVVINEQAAKTPSASFHRPAQAVSKWWKWDSFIDALKMALLAMSSHRMRTFLTMLGIIIGIASVVSVVALGNGSQQQILSNISSMGTNTIDVRPGKGFGDRRSGRVKTLTADDAKSLESLPFVDSVTPSLSNSLTVRYANQDATASVEGVGEDYFRVRGYEIAKGQFWDEESVNSLAQEAVIDDNTRKEMFADRNPIGEVIFLGSLPVRIVGVTQKKEDAFGNSDALKIWVPYTTMSGRMMGQRYLNGITVRIDENAPSAAVEQSIINLLKMRHGTEDFFTINTDTIRQSIEKTTATMTLLISAIAVISLIVGGIGVMNIMLVSVTERTKEIGVRMAVGARQADILRQFLIEAVLVCLCGGIAGIGLAFLIGFAFSTSGSSFQMIYSMNSIIWAFICSTLIGIAFGFLPARNAAKLDPIEALARD
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCFP_SALPB
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLVSYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVVFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRHDEALDSQRSAQALHPYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: RUVA_RICPR
Sequence: MIGKLNGKIDSHCDDYVIIDVNGVGYLVYASGKTLAKLVEGKFYKLFIETHVREEHIHLYGFLTLEEKNFFNLLQSVNGIGTKMALSILSNLTPTDIQIAINNDDRNIFKAISGVGAKLAERIMLELKDKITKIFSSSAIIKDSNISSIAINEVMKALVNLGFTRFEAQNTVQGIITQNPKISIDELIKTALKNRNSSF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RMA1_CAPAN
Sequence: MNQDMALEQLDTTFNKHDTPLGKWKSMNDEVEENISGGFDCNICLDCVHEPVITLCGHLYCWPCIYKWIYFQSVSSENSDQQQPQCPVCKAEVSEKTLIPLYGRGGQSTKPSEGKAPNLGIVIPQRPPSPRCGGHFLLPTTDSNPSQLLQRRGYQQQSQTRQPAYQGSYMSSPMLSPGGATANMLQHSMIGEVAYARIFGNSSTTMYTYPNSYNLAISSSPRMRRQLSQADRSLGRICFFLFCCFVTCLILF
What is the function of this protein?
E3 ubiquitin-protein ligase required for aquaporin levels regulation.
What are the official names of this protein?
E3 ubiquitin-protein ligase RMA1H1, Protein RING membrane-anchor 1 homolog 1, RING-type E3 ubiquitin transferase RMA1H1.
Protein: SAMC_MOUSE
Sequence: MDAPGFTASLVAGGVAGVSVDLILFPLDTIKTRLQSPQGFNKAGGFRGIYAGVPSAAVGSFPNAAAFFLTYEYVKSLLHTDSTSHFKPVKHMLAASTGEVVACLIRVPSEVVKQRAQVSASSKTLQIFLTILSEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWAWRRGHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIMLAKAGSSTAVGNVLSAMHGVWRSQGLAGLFAGVLPRMAAISMGGFIFLGAYDQARSLLLEVGRKSP
What is the function of this protein?
Mitochondrial S-adenosyl-L-methionine/S-adenosyl-L-homocysteine antiporter.  Mediates the exchange of cytosolic S-adenosyl-L-methionine, the predominant methyl-group donor for macromolecule methylation processes, for mitochondrial S-adenosylhomocysteine(SAH), a by-product of methylation reactions.
What are the official names of this protein?
Mitochondrial S-adenosylmethionine carrier protein, SAM carrier, Solute carrier family 25 member 26.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CAPSD_BPPH6
Sequence: MLLPVVARAAVPAIESAIAATPGLVSRIAAAIGSKVSPSAILAAVKSNPVVAGLTLAQIGSTGYDAYQQLLENHPEVAEMLKDLSFKADEIQPDFIGNLGQYREELELVEDAARFVGGMSNLIRLRQALELDIKYYGLKMQLNDMGYRS
What is the function of this protein?
Assembles to form an icosahedral capsid with a T=13 symmetry.  Drives the penetration of the inner capsid (core) into the cytoplasm.
What are the official names of this protein?
Major outer capsid protein, Protein P8.
What are the subcellular locations of this protein?
Virion. Note=Outer capsid protein (600 copies).
Protein: PLS10_PITHY
Sequence: FLSLIPHAINAVSALVHHF
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Phylloseptin-H10, PLS-H10, Phylloseptin-12, PS-12.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: H3_TALFU
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKAAPSTGGVKKPHRYKPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKSDLRFQSSAIGALQESVEAYLVSLFEDTNLCAIHAKRVTIQSKDIQLARRLRGERS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.