PharMolix/UniProtQA huggingface dataset:
Protein: AROA_STRA3
Sequence: MKLLTNANTLKGTIRVPGDKSISHRAIIFGSISQGVTRIVDVLRGEDVLSTIEAFKQMGVLIEDDGEIITIYGKGFAGLTQPNNLLDMGNSGTSMRLIAGVLAGQEFEVTMVGDNSLSKRPMDRIALPLSKMGARISGVTNRDLPPLKLQGTKKLKPIFYHLPVASAQVKSALIFAALQTKGESLIVEKEQTRNHTEDMIRQFGGHLDIKDKEIRLNGGQSLVGQDIRVPGDISSAAFWIVVGLIIPNSHIILENVGINETRTGILDVVSKMGGKIKLSSVDNQVKSATLTVDYSHLQATHISGAMIPRLIDELPIIALLATQAQGTTVIADAQELKVKETDRIQVVVESLKQMGADITATADGMIIRGNTPLHAASLDCHGDHRIGMMIAIAALLVKEGEVDLSGEEAINTSYPNFLEHLEGLVNA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PESC_SCHPO
Sequence: MARVKQKGKAGAARIYITRNQALKKLQLTLADFRRICILKGVYPREPKNKKKANKGSTAPVTFYYTKDIQYLLHEPIVQKFREYKVFARKLSKALGKGELETAKRLEARKPTYSLDHIIKERYPTFHDALKDIDDALSMLFLFSTMPVTDKIGAATVANCERLCAEFQHYVIRSNSLRKAFLSIKGIYYQAEIFGEQITWIVPYKFAQSVPTDVDFRIMHTFLEFYQALMGFVNFKLYNTLGLRYPPKIDVAKSESAAGLAAYELEESSSLPAIVHGNNKNARKNIATLKSKIRDIVNSDANVVEQSEKTTEDADEEPETEENLDEFKPADGADNEDSKSLVSHISSSNTSLFSNFTFFLSREVPRFSLEFVIRAFGGKVGWDPILGSGSPFSESDPVITHHICDRPHISQKYEGRIYIQPQWVYDSINKGILERTDLYACGATLPPHLSPFVKVGENDYDPEAELSAEENDDVSEALDDNISGEAVPISKKNDEPENVEQIDDAEEEDLEHQRELEAEAGGVAYSEYVKQNSKSAKKTKKRQRDTLTAEEKEEKEAKELSKMMMSNKQRKLYSKLKNENSKNENYNNALRNRKRDIEKRKKLKVEN
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Pescadillo homolog, Nucleolar protein 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: PURA_GEOSL
Sequence: MANVVVVGAQWGDEGKGKVVDIYTEHADDVVRYQGGNNAGHTLVVGEEKVVLHLIPSGILHEGKRCIIGNGVVLDPEVFIQEITRLKDKGRLKDDRALLVSESIHIIMPYHKRIDIAREAKSGEKKIGTTGRGIGPTYEDKIGRRGIRLMDLLDRDVFARKLKENLEEKNVILEKLLGDKPFTFEEIYEQYCGYADILRNYVADTSLILYNDSKAGKKLLFEGAQGTLLDVDHGTYPFVTSSSTCAGGACTGTGVSPRDIHEIIGISKAYVTRVGSGPFPTELLDADGEKLRQVGHEFGATTGRPRRCGWFDAMVVRYAVRVNGLTGVALTKLDVLNDFETIKVCTGYTFEGKPLADLPANLAVFEKCEPVYEELPGWMSDISGARTFEELPEKAKSYVKRLEQLIGCPIVLVSIGPRRDQTIIISNPFQDKV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMC_ECOSE
Sequence: MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRAHTQQFHHWQVLSRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLLPVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANCVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRAIMTRQAKKG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INAD_DROME
Sequence: MVQFLGKQGTAGELIHMVTLDKTGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGRLKVGDRILSLNGKDVRNSTEQAVIDLIKEADFKIELEIQTFDKSDEQQAKSDPRSNGYMQAKNKFNQEQTTNNNASGGQGMGQGQGQGQGMAGMNRQQSMQKRNTTFTASMRQKHSNYADEDDEDTRDMTGRIRTEAGYEIDRASAGNCKLNKQEKDRDKEQEDEFGYTMAKINKRYNMMKDLRRIEVQRDASKPLGLALAGHKDRQKMACFVAGVDPNGALGSVDIKPGDEIVEVNGNVLKNRCHLNASAVFKNVDGDKLVMITSRRKPNDEGMCVKPIKKFPTASDETKFIFDQFPKARTVQVRKEGFLGIMVIYGKHAEVGSGIFISDLREGSNAELAGVKVGDMLLAVNQDVTLESNYDDATGLLKRAEGVVTMILLTLKSEEAIKAEKAAEEKKKEEAKKEEEKPQEPATAEIKPNKKILIELKVEKKPMGVIVCGGKNNHVTTGCVITHVYPEGQVAADKRLKIFDHICDINGTPIHVGSMTTLKVHQLFHTTYEKAVTLTVFRADPPELEKFNVDLMKKAGKELGLSLSPNEIGCTIADLIQGQYPEIDSKLQRGDIITKFNGDALEGLPFQVCYALFKGANGKVSMEVTRPKPTLRTEAPKA
What is the function of this protein?
Involved in the negative feedback regulation of the light-activated signaling cascade in photoreceptors through a calcium-mediated process.  Interacts with tetrapeptide ligand located in C-terminal sequence of 3 key components of the visual cascade, tethering them and forming a macromolecular signaling phototransduction complex.
What are the official names of this protein?
Inactivation-no-after-potential D protein.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: STAR3_MACMU
Sequence: MSKLPGELARDLECSLPAVASLGSSLSHSQSLSSHLLPPPEKRRAISDVRRTFCLFVTFDLLFISLLWIIELNTNTGIRKNLEQEIIQYNFKTSFFDIFVLAFFRFSGLLLGYAVLRLQHWWVIAVTTLVSSAFLIVKVILSELLSKGAFGYLLPIVSFVLAWLETWFLDFKVLPQEAEEERWYLAAQAAVARGPLLFSGALSEGQFYSPPESFAGSDNESDEEVAGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFEKNNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLISYDVSAGAAGGMVSPRDFVNVRRIERRRDRYLSSGIATAHSAKPLTHKYVRGENGPGGFVVLKSASNPCVCTFVWILNTDLKGRLPRYLIHQSLAATMFEFAFHLRQRISELGARA
What is the function of this protein?
Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes (By similarity).  Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB (By similarity).  Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes (By similarity).  May also mediate cholesterol transport between other membranes, such as mitochondria membrane or cell membrane (By similarity).  However, such results need additional experimental evidences; probably mainly mediates cholesterol transport from the endoplasmic reticulum to endosomes (By similarity).  Does not activate transcriptional cholesterol sensing (By similarity).  Able to bind other lipids, such as lutein, a xanthophyll carotenoids that form the macular pigment of the retina (PubMed:21322544).
What are the official names of this protein?
StAR-related lipid transfer protein 3, Metastatic lymph node gene 64 protein, MLN 64, START domain-containing protein 3, StARD3.
What is the protein family that this protein belongs to?
Belongs to the STARD3 family.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Note=Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA, VAPB or MOSPD2.
Protein: ATG3_LODEL
Sequence: MLRSKLSSLREYLTPINHNSNFLTTGEISPEEFVKAGDYLVYKFPTWQWASCPKDLQKLFLPTDKQVLVTRHVPSHQRANEYFEGEFEVEIDEKDRDLALGNESNLKNGENGENDDEAEYGWIRSGRSSSEKGTGEVLDPQRVEEVNDIDELIDETAEGEEEEEEGEEGEGEGNGNGADFHADDDADYDDLDIVQGSHSKLRRYDLYITYSTSYRVPKLYLVGFDANGIPLLPQQMFEDINSDYKDKTATIEQLPVAHNTTSVSIHPCKHSSVMRVLMKHQRARREHENVAENMKRLSIGSEDHKEAMNHIRRLSAGSKELAQKQEEPNDSEIKVDLYLVIFLKFIASVTPGIEYDYTMDAL
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8.  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8.  The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme ATG3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURA_ECOUT
Sequence: MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: NUOK_LEGPC
Sequence: MIPVYDYLVLGVILFGLSLVGIMLNRKNIILLLVCVELMLLAVNTNFIAFSHYYNEVGGQVFVFFILTVAAAEAAIGLAIVMLLYRNRGNIDVDKMNHLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HTPG_LEGPA
Sequence: MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITISDNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGDGEFTIGYEKKLTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPILMKKLSEEGKESKEFETVNKATALWTLQKSEISEEEYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRFVKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLLRFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFAGKKLQSISKGKIELGDDETSEQIKEQEKTLEPLIKHIKSVLNDRVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQVPVSKPIFEINPDHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKB14_MOUSE
Sequence: MRFFLWNAILALWVTVLSGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPVWFTLGILEVLKGWDQGLKGMCVGEKRKLTVPPALGYGKEGKGKIPPESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWRLSKHEVKVYLQKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISAREFTYVHDEL
What is the function of this protein?
PPIase which accelerates the folding of proteins during protein synthesis.  Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen.  May also target type VI and type X collagens.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP14, PPIase FKBP14, FK506-binding protein 14, FKBP-14, Rotamase.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: LAT4A_LACTA
Sequence: MKFSIIALALAVAFVCVAESRSEEEGYDVSEEIQAEELEEAERGGIDRKLMEVVNNLRKVQGREDSEEAGRGGINRKLMEMVNNLRKVQGREDSEEAGRGGINRKLMEMVNNLRKVQGREDSEEAGRGGINRKLMEMVNNLRKVQGREDSEEAGRGGINRKLMEMVNNLRKVQGREDTEEARGLKDKFKSMGEKLKQYIQTWKAKFG
What is the function of this protein?
Shows no antimicrobial activity against Gram-positive bacterium B. subtilis B-501 or Gram-negative bacterium E. coli DH5-alpha at concentrations up to 20 uM.  Shows no toxicity towards insect (S. carnaria) larvae.
What are the official names of this protein?
M-zodatoxin-Lt4a, M-ZDTX-Lt4a.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 03 (latarcin) family. 04 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_ANADE
Sequence: MRVKKGFKARRRRNRVLKLAKGFRGRRKNCYRRANQAVERALNYSTRDRRLKRREFRALWIVRINAAARQNGTTYSKLVAALRKAGVEIDRKILADLALALPGDFAAIVKTAQA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ABCGC_DICDI
Sequence: MELQTIPNNISLANGDSKGVQLTFKNIVYKVDNKKYKKLVKKQEKAKKKNDTESSTGDMNTGVSTTIEKELTILNNVSGVIEKGELVALMGPSGSGKSTLLDILAQRKSTGKITGQLLVNGKEIGEAYKKYCSYVTQEDVLLQTSTVFETLKFYADLKLPGVSEIEKIKRVEQIIEDIGLTKRTHSKIGGVLPGGILMKGLSGGEKRRVSIGCGLVTNPSLIFLDEPTSGLDSVAALQIMKTLLNLTLKGVTVICSIHQPRPEIFALFNKVMVIIKGKMIYSGSNILEYFESLGYPCPNNTNPADFCLDSAVEIGEGERYTEICNQWQKIWENELLNEIEYPPVNVEKPKTASWGYQYWILLGRTWKDFLRNQGNFVARVGTAVVTGLLFGVCFAGLKETEADVQKILGTIFFLITGLNLTPFAVISLFLSGRTLFNAERASKIYHSFPYYMAMVTVETLIVFLVALINAAICYLFAHLRWTAGHFFFAIMVYFFVHLLSDFMISTIANLTGTSDMTFAYGSGLSVIYMLFAGFYVPTNELPKSFGWLHWVNPLFYSFVSLVVNQFEDLPLECTRPNIPVGNSTIQIPCQFSNGNQVIEYYGIDDWTRGSSFGVVVAWTVFFFWTSYLALHFLNKEKR
What are the official names of this protein?
ABC transporter G family member 12, ABC transporter ABCG.12.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPO6_THEPD
Sequence: MKIGPPWLTRFERARIIGIRALQISLGAPVLIQVSEELSDPITIAEKELELGLLPIIVVRWTPEGKIQEIPIKYLKLRPQL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo6, DNA-directed RNA polymerase subunit K.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_PIG
Sequence: MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_BUCAI
Sequence: MLINTEAVNEYLSFFMFIFFSLGLCFFMLCLSWILGGRSSSRYKNTPFESGIVSSGNTNLYFSVKFYLIAMFFVVFDVEALYLYAWSVSIKESGWIGFSEALMFGISLLLGLFYLVRIRALNWSSSVKNNIQLF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GTAO_DICDI
Sequence: TNNNNFNNINNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNYNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTSFNDNCNNNSNYHNHSNHHPLFESLQNINQYPLSPNNNKSSNQHLSHSSSNVNSQYYQTPYYQPSQKQNSPNSTPPLNGCQYENHNLNSNNTFFKKNTNHYISQQLYQQQFNQNVNNNNNNNNISNNNNNSYNINCNNNNNNNNSNYNNNSYNNNNNYNNNNNNNNNNNNNNNNNNNNNNIFNENNNNNNNNNNNNNNNCNNNYNNNDNNENKYCVPKIEIPQKNLQYSPPPFQLDSGSTTPKTPSAPTSPVLSPKTSNKICDLVLNIVPICQELSNEDGYQNKELLNKIQEYFEDAIREIKKIKKTRLPLMKQNHTKESDDKTFYSLRPRRNRKCTIKTKTLQSSNSEEIVCQACGTRASPEWRKGPDGFKSLCNACGLYYAKTKKRENEIIGQPDLIPKHMKIHNLIND
What are the official names of this protein?
GATA zinc finger domain-containing protein 15.
Protein: PWP2B_HUMAN
Sequence: MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARGVQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGSGPDRELRKPEEPENGEPTAAATARRSKRERREEDRAPAEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDDGSQDPEVLDRESRDRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRDSSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREGLAFLVSCPEGRADCASESACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSECITEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDGEPSWREAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANAARHVAPEIRELLTQFET
What is the function of this protein?
Chromatin-binding protein that acts as an adapter between distinct nucleosome components (H3K36me3 or H2A. Z) and chromatin-modifying complexes, contributing to the regulation of the levels of histone acetylation at actively transcribed genes (PubMed:30228260).  Competes with CHD4 and MBD3 for interaction with MTA1 to form a NuRD subcomplex, preventing the formation of full NuRD complex (containing CHD4 and MBD3), leading to recruitment of HDACs to gene promoters resulting in turn in the deacetylation of nearby H3K27 and H2A. Z (PubMed:30228260).  Plays a role in facilitating transcriptional elongation through regulation of histone acetylation (By similarity).  Negatively regulates brown adipocyte thermogenesis by interacting with and stabilizing HDAC1 at the UCP1 gene promoter, thereby promoting histone deacetylation at the promoter leading to the repression of UCP1 expression (By similarity).
What are the official names of this protein?
PWWP domain-containing protein 2B.
Protein: FETA_HORSE
Sequence: MKWVVSILLIFLLNSTESRTMHSNAYGIASALDSFQCSPEMNLVDLATIFFAQFVQEATYKEVSKMVKDVLTVTEKSTGSEQPTGCSENRLSAFLEEICHEEEIPEKYGLSGCCSQNEEERHNCLLARKKDSPASIPPFQVPEPVTSCKAYEENREMFLNRYLYEIARRHPFLYSSTALYLASHYDKIISACCKSENAVECFQSKAATITKELRETSLLNQHVCAVIRNFGPRTLQAITVTTLSQRYSKANFTEIQKLVLDVAHAHEECCRGNVEECVQDGEKLISYVCSQEDILSSSIVECCKLPTVELAQCIIHAENDDKPEGLSPNLNRLLGERDFNQFSSKEKDLFMARFTYEYSRRHTKLAVPVILRVAKGYQEFLEKCSQSENPLECQDKGEEELQKYIQEGQALAKRSCGLFQKLGDYYLQNAFLVAYTKKAPQLTPPELIALTRKMATAAATCCQLSEDKQLACGEQVAGLIIGQLCIRHEESPINPGVGQCCTSSYANRRPCFSSLVVDETYVPPPFSDDKFIFHKDLCQAQGVALQTMKQQFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQGQEVCFSEEGPQLISKTRAALGV
What is the function of this protein?
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
What are the official names of this protein?
Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMS_PECAS
Sequence: MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGLAVVDSEGHVARLRRLGKVQVLSQAAEEHELHGGTGIAHTRWATHGEPSEENAHPHISEHITIVHNGIIENHEPLRELMIGRGYRFVSETDTEVVAHLVHFEQKQNGGTLVEVVKRVIPQLRGAYGMVVLDNRDSSVLVAARSGSPLVIGRGVGENFIASDQLALLPVTRRFMFLEEGDVAEITRRDVRVFDKSGQLATREEIESKVSYDAGDKGAYRHYMQKEIYEQPMAIKNTLEGRFSHGEINLSELGPKADELLAKVEHVQIIACGTSYNSGMVSRYWFEALAGIPCDVEIASEFRYRKPAVRKNSLMITLSQSGETADTLAALRLSKELGYLGSLAICNVAGSSLVRESDMALMTKAGVEIGVASTKAFTTQLTVLLMLVARVGRLRGMDAQIEHDIVHGLQALPARIEQMLSQDKLIESLAEGFSDKHHALFLGRGDQYPIAMEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVVVVAPNNELLEKLKSNIEEVRARGGELYVFADEDAGFTSSENMKIIPLPHIEEVIAPIFYTVPLQLLSYHVALIKGTDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPE17_MYCTO
Sequence: MDFTIFPPEFNSLNIQGSARPFLVAANAWKNLSNELSYAASRFESEINGLITSWRGPSSTIMAAAVAPFRAWIVTTASLAELVADHISVVAGAYEAAHAAHVPLPVIETNRLTRLALATTNIFGIHTPAIFALDALYAQYWSQDGEAMNLYATMAAAAARLTPFSPPAPIANPGALARLYELIGSVSETVGSFAAPATKNLPSKLWTLLTKGTYPLTAARISSIPVEYVLAFVEGSNMGQMMGNLAMRSLTPTLKGPLELLPNAVRPAVSATLGNADTIGGLSVPPSWVADKSITPLAKAVPTSAPGGPSGTSWAQLGLASLAGGAVGAVAARTRSGVILRSPAAG
What is the function of this protein?
Induces pro-inflammatory responses.
What are the official names of this protein?
PPE family protein PPE17.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell surface.
Protein: RS16_PELPD
Sequence: MATKIRLARAGAKKRPFYQVVVADERSRRDGRFIENMGTYDPTKNPAVFKLNEEKILAWLSKGAQPTDTVRQLLKKAGILDKATA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: 5DNU_ECOSE
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.