PharMolix/UniProtQA huggingface dataset:
Protein: RS8_ACIB5
Sequence: MSMQDTVADMLTRVRNAQMAKKQTVSMPSSKLKVAIANVLQQEGYISNVEVAQEETKSTLTITLKYFEGKPVIEMVKRVSRPGLRQYRGKDKLPSVKQGLGIAIVSTSKGIMTDRAARAAGIGGEVIAFVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PP2AB_BOVIN
Sequence: MDDKAFTKDLDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL
What is the function of this protein?
Catalytic subunit of protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of a wide variety of enzymes, signal transduction pathways, and cellular events.  PP2A can modulate the activity of phosphorylase B kinase, casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, PP2A-beta.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles (By similarity).
Protein: H3L_ENCCU
Sequence: MSRTKQTASKALGGKAPRKGISAKSIPSSGCSPAMPKRTRFKAGALALKEIRKYQKSTDLLIRKRPFQRMVRDLCKGREGVRFQASAIVAFQEAVENFLTSLMEDAYRCVLHAKRVTLMPKDICLVYKIKYANILYAALD
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3-like protein.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YCIB_HAHCH
Sequence: MKLLFDFFPIILFFVVYKTTNDIVTATAALIPATAAQVAFSWFKYRKVEKMHLFALVIVVILGGATILFKDDTFIKWKPSVVCWLLAVVFLIGGWVSKKNLYQRMMEANISLPQHAWSKLNYSWVIFNTLLGALNLYVAYHYTQEQWVNFKLFGMLGLSLVFALMQGVYISRHMVEDEPAPSESATGNGDNKSF
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1095_STRZP
Sequence: MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASVFEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEMESILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILHYAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFSYREKTDLI
What are the official names of this protein?
UPF0758 protein SPP_1095.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RBFA_STAAT
Sequence: MSSMRAERVGEQMKKELMDIINNKVKDPRVGFITITDVVLTNDLSQAKVFLTVLGNDKEVENTFKALDKAKGFIKSELGSRMRLRIMPELMYEYDQSIEYGNKIERMIQDLHKQDR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENC_STAAC
Sequence: MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAYFGECNAFQTDWYDHETIASVKHVIEQWFEDNRNKSFETYEAALKLVDSLENTPAARATIVMALYQMFHVLPSFSVAYGATASGLSNKQLESLKATKPTRIKLKWTPQIMHQIRVLRELDFHFQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFKDISMLDEVADGTIPPIALDEKATSLLDIINLIELYNVKVVVLKPFRLGGIDKVQTAIDTLKSHGAKVVIGGMYEYGLSRYFTAMLARKGDYPGDVTPAGYYFEQDVVAHSGILKEGRLEFRPPLVDITQLQPY
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24872444).  Does not show N-succinylamino acid racemase (NSAR) activity with N-succinyl-L-phenylglycine as substrate (PubMed:24872444).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
Protein: MSHC_MYCUA
Sequence: MQSWSSAPVPIVPGREPELRLYDTADRQVRPVAPGNTATMYVCGITPYDATHLGHAATYLAFDLIHRLWLDLGHEVRYVQNVTDVDDPLFERADRDGVDWRDLAAQEVALFREDMAALRVLSPHDYVGATEAVAEIIELVEKLLASGAAYVLDGEHPDVYYRSDATLQFGYESGYDRDTMLGLFEQRGGDPGRPGKNDALDALLWRAARPGEPSWPSPFGPGRPGWHIECAAIALSRVGSGLDVQGGGSDLIFPHHEFTAAHAECVTGEQRFARHYVHAGMIGWDGHKMSKSRGNLVLVSGLRAEGVNPAAVRLGLLAGHYRADRFWSQQVLDEAVGRLQRWRAATTLPAGPDAAAVVARVRQYLADDLNTPKAIAALDGWATDALDYGGHDEVAPRLVASTIDALLGVDL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: VG17_BPB03
Sequence: MNNYQLTIKEVLYIIKTSRNYGKKSSAKLHTITVKELITDVLNLKYTIDIILTELNSVDRVKMNNYMLAILEAVEYIEDTQEIISSLSNKDTSAKGLSKLPKPRLVEIFLRLENLMYRIEDILEVTNND
What is the function of this protein?
This protein is involved in the replication of the phage DNA.
What are the official names of this protein?
Early protein GP17.
What is the protein family that this protein belongs to?
Belongs to the podoviruses GP17 family.
Protein: SYR_METST
Sequence: MYSKLKTEINESIKEALTKLRIKYDDEIILEEPPNPSMGDMSTNIAFSLASKLKKSPVEIAQEIKENIKLPLYFEKVETKGPYINFYINYTLFTTKVVNYIDKNYGELPEKDERILLEHTSANPNGPLHVGHLRNAILGDSLKRILQHAGYKVEAQYYVNDMGRQIAIIVWGMDKFNYTVDDDKKADHAIGEVYYKCNQQLEANPEYNQEIDDILRKYEEGTDAALIDAFQGVVEYCIDGIKETLKDLNIKMNLFKWESTFLRNGSVDDVLEKLQPFTIQKDILYLPLERYNVDKELVLRRSNGTSLYATRDLAYHQYKTKNSDISLDILGADHKLAAKQLGLALELSNNRAPEVVFYEFIDLPEGSMSTRKGVFISVDEFIEQSVEHAKEELIRRDLDLTEKQIEEVSKIVGVGSIRFYINQISPEKPITFKWEEALSFERGCASIQYAHARACKLLAKSDYNEFEEVRCDYELDDEEKDLIKTLSQFTEVICQSAQERRVHHLAQYTLSLSKAFNKFYKSKQVIGSEHEKLRLKLVDASRITLKNSLKLLGIKSPEFM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_SALG2
Sequence: MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: POTA_MESH7
Sequence: MKNIEKSEIIISLVDVDKEFGDKKVLDQINLDIKRGDFVTLLGPSGSGKTTILRLIGGFEWTTRGEIKFNGIDIKDVPAHKRDTATIFQDYALFPHLSVRGNIEFGLKLKRIKKKAEEIPDVVWKKFEHLKKKWQDKQKRKIKELKILQAHLEKLLENPQLDIKKRKKLQDKLDDSDFRYSNWENYLTSKSESFKKKYLTRKITKQEINKEITDIIDLVGLTGNENRAISELSGGMKQRVALARSLVIEPEIVLLDEPLSALDTKIRQKMQVFLKKIQQKLGLTFIFVTHDQDEALQLSDKIAIIRNGKIAQYDEPKQIYDYPVNKWVANFIGDSNFFQAKYIKKNQVEILGLKLYTIHDEFIPGQKLDCLIRPEDIDIDLDSGYFKGKVIQNIYKGSYYSLDIKVENTIINVETNDFYDLETQVFIKWDDDAIHLMEMENAEI
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYK_ACIBT
Sequence: MTQQNAQSTSEPTISENDLIAQRHAKLKQIQDVAKETGKSPWPNTFKREHYAADLQEQFKDQSKEQIESAEHVYVKVAGRVMLNRGSFMVIQDMTGRIQLYVDRKGLPKDTLETIKGLDLGDIIAAEGYIGRSGKGDLYVHLEGFELLTKSLRPLPDKFHGLNDTEVKYRKRYLDLIVNEETRKTFEIRAKVVAGIRAFLTNERFMEVETPMMHVIPGGASARPFETHHNALDMPLFLRIAPELYLKRLVVGGFERVFEINRNFRNEGVSTRHNPEFTMIEFYQAYADYKDLMALTENMLEKLAIDILGTTDVPYQGEVFSFKGPFKKISMFDAILENNPQFTPENVGDREFLAKFVREELKEEVKPGFGLGKLQTIVFEETVETKLRQPTFITEYPAETSPLARRNDDNPHITDRFEFFIGGRELANGFSELNDPIDQAERFQAQVAEKDAGDDEAMHYDAEFVEALEYGLPPTAGEGIGIDRLVMLFADAPSIRDVILFPHMRRKEG
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_GLUOX
Sequence: MTETGSSLMSDKTPDPSVAAFKEQQDRYRDTVFLPRTGFPMRGGLPKREPETLARWAATGLDEKIREAGKGRPVFTLHDGPPYANGHIHIGHALNKVMKDVINRAHRMSGYEVRYLPGWDCHGLPIEWRIEEQYRKAGKDKDQVPLLQFRAECRQYAAQWVQKQAEDFKRIGVQAEWANRYVTMDFSSEAKIVDEIGKFLLNGSLYRGLRPVMWSPVEKTALAEAEIEYHDIDSTTIFVAFPIIKDPTPAHALNGVSAVIWTTTPWTIPANRALAYGPDITYVVLRVDETNENSVVPQGAKLLVAEDRVDAFCTETGITAHHILYTLPGNGLEGAVCAHPLRGRGYEYDVPMLPGDFVTTDAGTGLVHMAPSHGQDDFMLCRQYGIEVPELVQDDGRYAPWVPHLAGIHVFKAADPVCDLLTEARQSAEHDDAPATGLMARGTVRHSYPHSWRSKAPIIFRATPQWFIAMDGETKLREKSLSALDNVTFVPEAARRRLTSMIEQRPDWCISRQRAWGVPIAVFVEKRTGEVLRDAAVMQRIVEAFREKGADIWYEADPSLFLGEGRNPADYEQVFDIVDVWFESGSTHRFDLGQEGLNFPADLYLEGSDQHRGWFQSSLLESVGTMGVAPYKALVTNGFVMDEQGRKMSKSLGNVVAPSDVTESLGADILRLWVLNSDTNEDLRIGQDILKQQGELYRRLRNTLRWLLGALDGFTPEEAVSYADLPPLEQYILHRLTELRGLIASAVETHQWVGVYPALHGFCTTDLSAFYFDIRKDAIYCDAPSDPTRRAARTVLDALHRALCTWLAPVLVFTAEEAWQARFGEDDSVHLAQFFEPEAEWNDPELGNRWEDIRAYRRLITTELETARRDGTIGSSLEASVTLPLSQEEAGIFGGLDWAELLITSHAETELLPGDTAHGGPQVERAPGHKCARCWKVLPEVGENTEHPALCRRCIDVVSA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTU2_CULQU
Sequence: MCSIVEDDFGDEGGAHTMKEESPAPAISATTDGEELCRKCTVNPSVLKLNLKEPQCRECFLHYVRHKFRASLGATKIVRRGSRVLVVFSGSAENVVMLDMIRYGLQQESFKKLRIEPVVVFVSEDHVGREDGERVGVVQEKVRILKQFEFRSYFSVIGAKECVAVEDSDLLERYSEERARFNKILSGFKSATSKQDFIVQNRKQTLKVIAKRLDCPYVFLSDIGLDLAKTLLSNVALGRGRSLALDIAFCDDRDEQHKIIRPMRDLNPDEIENYLKHADNELSYITLEDPFKDKPSLQNLTCKFVDGLQRTYPSTVSTVFRTGDKMSCETVKPTAENDDDQDLLSLFDQSLRLNSSSTSVRCKFCHSALDFHGSTTLFATEFSRMVSSRINVELSHEAIVESSKRMEEDARRRVNGEEVDGGEGS
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_PECCP
Sequence: MSTYLVGDVHGCLVELKALLAQVSFNPEQDTLWLTGDLVARGPDSLQVLRFVRSLGSAVRMVLGNHDLHLLAVYAGISRNKPKDRISDLLTAPDADELINWLRRQPILQVDDDLKLVMAHAGITPQWDLPTAQMCAREVEAILSSDSYPLFLDAMYGDMPNHWSPELSGLARLRFSTNVFTRMRYCFSGGQLDMLCKEPPSQAPSLLKPWFDLPSQVAGEYAIAFGHWASLEGKGTPENIYALDTGCCWGGELTMLRWDDKRYFTQSSLSSNTESSGDIAL
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: CTU2_DROWI
Sequence: MCSIGEDDFGDTGGLHAMTAGGPVQIATGGTGECQKCGQHSDDLFKVNFRSEECRDCFLNYARHKFRAALGAAKALPRDSDVLLLLDGSIESIVLLDMLHYAQTQNTFKRLHCQAKVLYLDESVVQEQQSLDIDRLQKLQDRYTPFDLFVIELGTDLSNLRPLKNYTPKTSREESDLKIKLDKLRTLSARQDYLQQQRKRFLASVAHQLNCTHVFVPSISKDLATQFLTSIALGRGGSAALDVALCDDRLDHDIKLLRPLKDLNEQEVQLYVRARNLEDLKLGPSLATYGQEKGETASLQNLTAAFVRNLQENYAATVSTVFRTGNKIAPNRHVDQDMCQQCQSPLDSLLSDTLLAIEYSRVVSLEGSKLSNHNNDLEQLSMQRLNKDDRLCHACRNVQDEYL
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLDH_MYCTU
Sequence: MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGLTEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF
What is the function of this protein?
Appears to be essential for Mtb pathogenesis.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, LPD, Component of peroxynitrite reductase/peroxidase complex, Component of PNR/P, Dihydrolipoamide dehydrogenase, E3 component of alpha-ketoacid dehydrogenase complexes.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBPS2_XENLA
Sequence: MSGIKSDTEHNNNNIEEEVRTLFVSGLPIDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVTFDNRAGAEAAKNALNGIRFDPENPQTLRLEFAKANTKMAKNKLMATPNPTNFHPALGAHFIARDPYDFTGAALIPASPEAWAPYPLYTAELAPAIPHAAFTYPAAAAAALHAQMRWYPPSEATQQGWKSRQFC
What is the function of this protein?
RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (By similarity).  Binds NOG mRNA, the major inhibitor of the bone morphogenetic protein (BMP) pathway.  Mediates an increase of NOG mRNA levels, thereby contributing to the negative regulation of BMP signaling pathway and promoting reversible dedifferentiation and proliferation of smooth muscle cells (By similarity).
What are the official names of this protein?
RNA-binding protein with multiple splicing 2, Heart and RRM expressed sequence, Hermes.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_TERTT
Sequence: MASSQLAKEIAKRRTFAIISHPDAGKTTITEKLLLFGNAIQLAGSVKGKRGPHAKSDWMTMEQERGISVTSSVMQFPYKERVVNLLDTPGHEDFSEDTYRTLTAVDSVLMVIDGAKGVEDRTIKLMEVCRLRDTPILSFINKMDRDIRDPVEVMDEIEDVLKIAAAPINWPIGMGKEFKGVYNLYTDTIHLYEHGQGHTIPEDIQIKGLDSEEASALLGAYAEDVREEIELVRGATHEFDLDAYHAGELTPVFFGTALGNFGVREMLDGFVEWAPAPLDRDTAERKVAADEDKFSGFIFKIQANMDPKHRDRIAFMRVCSGRYSQGMKMRHVRLGKDVKIADAVTFLAGDRSQVEEAISGDIIGLHNHGTIQIGDTFSSGEILKFTGIPHFAPELFRRIRLKDPLKTKQLQRGLQQLSEEGSTQVFFPLNNNDIVVGAVGVLQFEVVAYRLKDEYKVEAIYEPVNVNTARWVDCSDDKKLAEFKRKCSDNLALDGGGHLTYLAPTRVNLSLSEERYPDVAFRATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_STAA9
Sequence: MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGLRLQNRKLRRPDLTFATLDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGIIQPDDITFEYVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEMGVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVKGNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAIHGKFVDVRKVVV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RL31B_CORGL
Sequence: MKKDIHPDYHAVVFQDAGTGFQFLTKSTASSDRTVSWEDGNEYPLIVVDVTSESHPFWTGAQRVMDTAGRVEKFERRFGGMARRKKKA
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: CISY_DAUCA
Sequence: MVFFRSVSLLNKLRSRAVQQSNLSNTVRWFQVQTSASDLDLRSQLKELIPEQQERIKKLKAEHGKVQLGNITVDMVLGGMRGMTGLLWETSLLDPEEGIRFRGLSIPECQKLLPGAKPGGEPLPEGLLWLLLTGKVPTKEQVDALSAELRSRAAVPEHVYKTIDALPVTAHPMTQFATGVMALQVQSEFQKAYEKGIHKTKYWEPTYEDSITLIAQLPVVAAYIYRRMYKNGQSISTDDSLDYGANFAHMLGYDSPSMQELMRLYVTIHTDHEGGNVSAHTGHLVASALSDPYLSFAAALNGLAGPLHGLANQEVLLWIKSVVSECGENVTKEQLKDYIWKTLNSGKVVPGYGHGVLRNTDPRYICQREFALKHLPDDPLFQLVSNLFEVVPPILTELGKVKNPWPNVDAHSGVLLNHYGLTEARYYTVLFGVSRAIGICSQLVWDRALGLPLERPKSVTMEWLENHCKKSS
What are the official names of this protein?
Citrate synthase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: 3S11_NAJHA
Sequence: LECHNQQSSQPPTTKTCPGETNCYKKRWRDHRGSITERGCGCPSVKKGIEINCCTTDKCNN
What is the function of this protein?
Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site.  Binds to the muscular nicotinic acetylcholine receptor.
What are the official names of this protein?
Short neurotoxin 1, Neurotoxin alpha.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMM_YERPB
Sequence: MNNKIALYCRSGFEKECAAEITEKAAQLEIFGFARVKENSGYVLFECYQLEDADRLIREIPFREFIFARQMMVVGELLKDLPPEDRVSPIVGMLVGVIEKAGELRVEVADTNESKELLKFCRKLTVPLRSALREQKILSARENAHRPVVHVFFIAPGCCYVGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWEERLASGMHAVDLGACPGGWTYQLVQRSMMIQAVDNGLMAQSLMDTGQVTHHRADGFKYEPTRSNIYWLVCDMVEKPTKVTQLITKWLVNGWCREAIFNLKLPMKKRYEEVVQNLAMMDEQLKENGINADIHAKQLYHDREEVTVHVRRIWSGAPGRRDERY
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLT11_YARLI
Sequence: MQTTKSDTNKITWEDTEVPAVCTQCLGANPYIRMTKEKYGAECKMCTRPFTVFRWQPERAQKGSSRGKPLKTNVCLTCSRQKNCCQSCSLDLTYGLPLAIRDAALKMEQEGGGGGLSLSSSSNTITKQFIAQNYEEQLKQDQRLLTDNSVTGTGKAQSAAKGLLKQLANAMPYRKELYEKGQKDKRPADSRDSKALTADVTKIASKLPLTGSTTPVPKDASIKSLFFMGVEDDLPEHVIRKHFTETGGTISLLTVVHRAHCGYVVFETRAAAEKAAAAISGGRLVLNGCRLRVAWGKPRNLGSSSDEQWKLGQMIKKYLRSKGGSSNKDGAAGRDEAAPPPPGQGIKYQSQGNIEL
What is the function of this protein?
Involved in pre-mRNA splicing.  Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome.  Binds to RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor SLT11.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRTXL_ATRMM
Sequence: IWDEPVVVSARDTEEAARVPSPQKRSQPLCSCNDINDKECMYFCHQDVIWDEPVVVSVRDTEEAARVPSPQKRPQPRCSCNDMNDKECMYFCHQDVIWDEPVVVSVRDTEEAARVPSPQKRSQPRCSCNDMNDKECVYFCHLDIIWDEPVVVSVRDTEEATRVPSPQKRSQPLCSCNDINDKECMYFCHQDIIWDEPVVVSVRDTEEAARVPSPQKRSQPLCSCNDINDKECMYFCHQDIIWDEPVVVSVRDTEEAARVPSPQKRSQPLCSCNDINDKECMYFCHQDVIWDEPVVVSVQDTEEAARVPSPQKRSQPLCSCNNMSDKECLNFCNLDIIWENVDTSADPEFLG
What is the function of this protein?
Vasoconstrictor activity.  Causes cardiac arrest probably as a result of coronary vasospasm (By similarity).  Displays low agonistic activities towards endothelin-2 receptor (EDNRB) (displays affinity in the micromolar range) (PubMed:21889567).
What are the official names of this protein?
Long-sarafotoxin, L-SRTX.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: APT_HISS2
Sequence: MNKLELIKSSIKSIPNHPKEGIIFRDITSLTEVPEAFQATIDLIIERYKSKGITKVIGTESRGFIFGAPVALALNVPFILVRKPGKLPRETIAQSYQLEYGQDTLEMHVSSIQAGDNVLVIDDLLATGGTIEATVKLVERLQGQVKHAAFVISLPDLGGEVRLRELGVEPFTLVEFSGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A29AB_DROSI
Sequence: MYATNLLYLLALWNLWLVSGGQQDIPNGNATLPSPQKPQNTIDQIGANQNYWFTYNALRQNETLAIIDAMESGIASSVLAFQAQMEIQLQPLKIIMLHHAGNIKASNNIKMSRFEKVGSRYFHIEKNLTLTWFEAYVTCREMNGHLANIRDEKELDGILALAPNNSYWVDISKLVEYGGTFVSTLTGREPIFVKWKPNQDKKKQHNCVYIYAKEMYYDECFEKKSFVCQANQWA
What is the function of this protein?
Responsible for physiological and behavioral changes in mated female flies.
What are the official names of this protein?
Accessory gland protein Acp29AB.
What are the subcellular locations of this protein?
Secreted.