PharMolix/UniProtQA huggingface dataset:
Protein: DHAS_MYCTU
Sequence: MGLSIGIVGATGQVGQVMRTLLDERDFPASAVRFFASARSQGRKLAFRGQEIEVEDAETADPSGLDIALFSAGSAMSKVQAPRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFERDAHRRPKGIIANPNCTTMAAMPVLKVLHDEARLVRLVVSSYQAVSGSGLAGVAELAEQARAVIGGAEQLVYDGGALEFPPPNTYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRFESRKILGIPDLLVSGTCVRVPVFTGHSLSINAEFAQPLSPERARELLDGATGVQLVDVPTPLAAAGVDESLVGRIRRDPGVPDGRGLALFVSGDNLRKGAALNTIQIAELLTADL
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate (PubMed:15752328).  Is essential for the growth and pathogenicity of M. tuberculosis, and for the generation of the bacterial cell wall (PubMed:26437401).
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: RBL2A_HUMAN
Sequence: MAEDKTKPSELDQGKYDADDNVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDIQRKVTYRNLSTWYTELREFRPEIPCIVVANKIDDINVTQKSFNFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVSYKQNSQDFMDEIFQELENFSLEQEEEDVPDQEQSSSIETPSEEVASPHS
What is the function of this protein?
Plays an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.  Binds, in a GTP-regulated manner, to a specific set of effector proteins including key proteins involved in cilia development and function and delivers them into the growing sperm tail.
What are the official names of this protein?
Rab-like protein 2A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: EMBC_MYCTO
Sequence: MATEAAPPRIAVRLPSTSVRDAGANYRIARYVAVVAGLLGAVLAIATPLLPVNQTTAQLNWPQNGTFASVEAPLIGYVATDLNITVPCQAAAGLAGSQNTGKTVLLSTVPKQAPKAVDRGLLLQRANDDLVLVVRNVPLVTAPLSQVLGPTCQRLTFTAHADRVAAEFVGLVQGPNAEHPGAPLRGERSGYDFRPQIVGVFTDLAGPAPPGLSFSASVDTRYSSSPTPLKMAAMILGVALTGAALVALHILDTADGMRHRRFLPARWWSTGGLDTLVIAVLVWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTPEAPFGWYYDLLALWAHVSTASIWMRLPTLAMALTCWWVISREVIPRLGHAVKTSRAAAWTAAGMFLAVWLPLDNGLRPEPIIALGILLTWCSVERAVATSRLLPVAIACIIGALTLFSGPTGIASIGALLVAIGPLRTILHRRSRRFGVLPLVAPILAAATVTAIPIFRDQTFAGEIQANLLKRAVGPSLKWFDEHIRYERLFMASPDGSIARRFAVLALVLALAVSVAMSLRKGRIPGTAAGPSRRIIGITIISFLAMMFTPTKWTHHFGVFAGLAGSLGALAAVAVTGAAMRSRRNRTVFAAVVVFVLALSFASVNGWWYVSNFGVPWSNSFPKWRWSLTTALLELTVLVLLLAAWFHFVANGDGRRTARPTRFRARLAGIVQSPLAIATWLLVLFEVVSLTQAMISQYPAWSVGRSNLQALAGKTCGLAEDVLVELDPNAGMLAPVTAPLADALGAGLSEAFTPNGIPADVTADPVMERPGDRSFLNDDGLITGSEPGTEGGTTAAPGINGSRARLPYNLDPARTPVLGSWRAGVQVPAMLRSGWYRLPTNEQRDRAPLLVVTAAGRFDSREVRLQWATDEQAAAGHHGGSMEFADVGAAPAWRNLRAPLSAIPSTATQVRLVADDQDLAPQHWIALTPPRIPRVRTLQNVVGAADPLFLDWLVGLAFPCQRPFGHQYGVDETPKWRILPDRFGAEANSPVMDHNGGGPLGITELLMRATTVASYLKDDWFRDWGALQRLTPYYPDAQPADLNLGTVTRSGLWSPAPLRRG
What is the function of this protein?
Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
What are the official names of this protein?
Probable arabinosyltransferase C.
What is the protein family that this protein belongs to?
Belongs to the emb family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYL_STRZT
Sequence: MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVAYLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVTTDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYIDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_MANSM
Sequence: MTNYFDKIEKVKYEGADSTNPFAYKHYNANEVILGKTMAEHLRLAVCYWHTFCWNGNDMFGVGSLDRSWQKMSDPLAAAKQKADIAFEFLTKLGVPYYCFHDVDIAPEGNSYQEYVRNFNTIVDILEQKQAESGVKLLWGTANCFSNPRYMSGAATNPNPEIFTRAAAQVFNAMNATKRLGGENYVLWGGREGYETLLNTDLRREREQIGRFMQMVVEHKHKIGFSGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHTFQHEIATAAALDILGSIDANRGDPQLGWDTDQFPNSVEENTLAIYEILKAGGLTTGGFNFDAKIRRQSINPYDLFHGHIGAIDVLALSLKRAAKMVEDHTLQNIVDQRYAGWNGELGQQILAGKSSLEALAQAAQNLDPNPVSGQQEYIENLVNGYIYR
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBK_ORYSJ
Sequence: MPNILSLTCICFNSVIYPTSFFFAKLPEAYAIFNPIVDFMPVIPVLFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: JHD1_CANAL
Sequence: MPINSESCPLCKVHSNTIKKEDEDEEDNKTSWIQCSKCKVWYHVHCLDLPTDEIDQIVIYHCPECVPKYGESTYKRKSKRARVSIDYQSLNEGDTFAIDKSSHFHLHNFLNFKGETNINVIDKLTKTYALNTQMEKPILIPQADLSKNGMQLPIEKNEITIDYITDCCGEDTPLEVMDVISQQGISPPWKLKQWREYFKTNEEKRDRIRNVISLEISDVAKLGVDFTRPKCVRDMDVVDRVWIEEDEQKRSKVTKYCLMSVKNSFTDFHIDFGGTSVYYTVLSGAKTFLFFPPTDNNLELYKSWCLEPSQNFIWYPEYTITKNKKKIKPTGGFKVDLQPGDLFIIPSGWIHAVHTPQDSIVIGGNYLTIRDMVMQLKINEIERETKVPTKFRFPMFNKVLWLTAWYYYNHQNEFQSDIGEDEDGNAILTRLIGHLQGHLELSKTNATAKRSIPKTIGKPMVFINKLLAWKEDLYGTAV
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.
What are the official names of this protein?
JmjC domain-containing histone demethylation protein 1, [Histone-H3]-lysine-36 demethylase 1.
What is the protein family that this protein belongs to?
Belongs to the JHDM1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS12_TREPR
Sequence: MPTLNQLVRQGRRRFEARSKSPALRGCPQLRGVCTKVYTTTPKKPNSALRKVAKVRLSNRLEVISYIGGEGHNLQEHSMVLVRGGRVKDLPGVRYHIVRGALDAGGVRERRRSRSKYGAKMPRSAA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: LEPA_STAA8
Sequence: MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCVLRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: C7104_ARATH
Sequence: MVSSVSLFASLTPYLVSALLLFLLLEQLFYRVKKRNLPGPLFVFPIIGNVVALIRDPTSFWDKQSAMADTSVGLSVNYLIGKFIIYIKDAELSNKVLSNIRPDAFQLTGHPFGKKLFGDHSLIFMFGEDHKSVRRQVAPNFTRKPLSAYSSLQQIVILRHLRQWEESFSSGSRPVSMRQLIRELNLETSQTVFVGPYLDKEVKKTICDDYSLLTLGTMAIPIDLPGFTFGEARQAVSRLVNTMSVCVGKSKAKMAAGENPTCLVDFWTHSIIEENPPPPHSKDKEISCVLVDFMFASQDASTSSLLWAVVMLESEPEVLRRVREDVARFWSSESNELITADQLAEMKYTRAVAREVLRYRPPASMIPHVAVSDFRLTESYTIPKGTIVFPSLFDASFQGFTEPDRFDPDRFSETRQEDEVFKRNFLTFGNGSHQCVGQRYAMNHLVLFIAMFSSMFDFKRVRSDGCDDIVHIPTMSPKDGCTVFLSSRLVTSP
What is the function of this protein?
Required to form the C-22 double bond in the sterol side chain.  Possesses C-22 desaturase activity toward beta-sitosterol and produces stigmasterol.
What are the official names of this protein?
Cytochrome P450 710A4, C-22 sterol desaturase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: UCHL1_HORSE
Sequence: MQLKPMEINPEMLNKVLARLGVAGQWRFVDVLGLEEETLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLEFEDGSVLKQFLSETEKLSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDLLLQDAAKVCREFTEREQGEVRFSAVALCKAA
What is the function of this protein?
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins.  This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (By similarity).  Also binds to free monoubiquitin and may prevent its degradation in lysosomes (By similarity).  The homodimer may have ATP-independent ubiquitin ligase activity (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Lipid-anchor.
Protein: NMES1_HUMAN
Sequence: MSFFQLLMKRKELIPLVVFMTVAAGGASSFAVYSLWKTDVILDRKKNPEPWETVDPTVPQKLITINQQWKPIEELQNVQRVTK
What are the official names of this protein?
Normal mucosa of esophagus-specific gene 1 protein, Protein FOAP-11.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA4 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALF2_LETCA
Sequence: MAALYPALTPEQKKELAEIAQRIVSNGKGILAADESTGTMGKRLSAIKVENVDENRRVYRQLLFSSDPSVTKAIGGVIFYEETLYQKTDDGTPFVKLIKDRGIVVGIKVDKGTVPLAGTDGESTTQGLDGLAERCARYKKDGADFAKWRCVLKISKNTPSALAIAENANVLARYASICQQNGLVPIVEPEILPDGDHDLKTCQYVTEKVLAATYKALSDHHVYLEGSLLKPNMVTAGQASKIRCSPQEVAMATVTALRRTVPSAVPGITFLSGGQSEEDASLNLNAINQLPLERPWALSFSYGRALQASVLKAWAGAPANIPAAKKEFEKRAAINGLAAQGKYVPAGSSGSAASESLFIANHNY
What are the official names of this protein?
Fructose-bisphosphate aldolase, non-muscle type.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: ALLA_ECOK1
Sequence: MKLQVLPLSQEAFSAYGDVIETQKRDFFHINNGLVERYHDLALVEILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDLSTLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the anaerobic utilization of allantoin as sole nitrogen source.  Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: COBQ_SACD2
Sequence: MTTTLMIQGTTSDAGKTTLVAALCRILARKGIKVAPFKPQNMALNSAVTEDGGEIGRGQAVQAQAAGIAPHTDMNPILLKPSTDTGAQVIVHGKALSAMEADAYHDYKKVAMQAVLESYRRLQTQYQVIVVEGAGSPAEINLREGDIANMGFAEEVDCPVIIIADIDKGGVFAHLVGTLELLSASEQKRVVGFVINRFRGDIELLKPGLTWLEQKTNKPVLGVIPYIQKLHLEAEDALTANSTAENTQHLKIRVPVWQRISNHTDFDPLRLHPQVDFAFVGPGQSLEGADLIILPGTKNTIADLNFMRSQGWDTQLAKHLRYGGKVLGICGGLQMLGTALHDPHGIESPASSVNGLGYLDFETTFTQHKTLLNLQGELHINDKPVAISGYEIHAGLSTGPAFQRPIIYCEGQPEGCRSADDQIIATYWHGLFSQPSATQALLAWAGLTNARALDYSALIETELTRLADEVEQCMDIDALFPTFAS
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: F174B_MOUSE
Sequence: MSALPPQPPPPLLLLLLALLAAPAALARRAESASASQPEAEHQPPPGPGNATQLGSGMAGGGSSNSSVDAVVTRISSLLRDLPTLKATVIVACAFSALLIACLLLRVFRLGKRLKKTRKYDIITTPAERVEMAPLNEEDDEDEDSTVFDIKYR
What is the function of this protein?
Essential for Golgi structural integrity.
What are the official names of this protein?
Membrane protein FAM174B.
What is the protein family that this protein belongs to?
Belongs to the FAM174 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Golgi apparatus.
Protein: SNW1_PONAB
Sequence: MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGDGGAFPEIHVAQYPLDMGRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKVTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  Required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA.  May recruit PPIL1 to the spliceosome.  May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.  Involved in transcriptional regulation.  Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1-mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1.  Is involved in NOTCH1-mediated transcriptional activation.  Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD.
What are the official names of this protein?
SNW domain-containing protein 1, Nuclear protein SkiP, Ski-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the SNW family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SAES_STAAB
Sequence: MVLSIRSQIIIGVVSSILLTSTILAIAYILMWFNGHMTLTLTLTTIITSCLTLLICSIFINPLIQKIKQFNIKTKQFANGNYASNDKTFNSPKEIYELNQSFNKMASEITQQMNQIKSEQQEKTELIQNLAHDLKTPLASIISYSEGLRDGIITKDHEIKESYDILIKQANRLSTLFDDMTHIITLNTGKTYPPELIQLDQLLVSILQPYEQRIKHENRTLEVNFCSEIDAFYQYRTPLERILTNLLDNALKFSNVGSRIDINISENKDQDTIDIAISDEGIGIIPELQERIFERTFRVENSRNTKTGGSGLGLYIANELAQQNNAKISVSSDIDVGTTMTVTLHKLDITS
What is the function of this protein?
Member of the two-component regulatory system SaeR/SaeS involved in the regulation of staphylococcal virulence factors in a strain-dependent fashion.  Probably functions as a membrane-associated protein kinase that upon sensing the appropriate signal, autophosphorylates and in turn activates the cytosolic response regulator SaeR (By similarity).
What are the official names of this protein?
Histidine protein kinase SaeS, Sensor protein SaeS, Staphylococcus exoprotein expression protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ADA11_XENLA
Sequence: RRHHSPLLVSLIGGQTFKSSHSGAAYFGGICSPTHGGGVNEYGNIGAMAITLAQTLGQNLGMMWNKPRTTTGDCKCPDLWRGCIMEDTGFYLPQKFSRCSVDEYSKFLQDGGGSCLFNKPLKLLDPPSCGNGFIEIGEECDCGSPAECNKSRAGNCCKKCTLSHDAMCSDGLCCRGCKYEPRGTVCRESLNECDVPEACPGDSSACPANLHKQDGYFCDNEQGRCFGGRCKTRDRQCHALWGRGASDRFCYEKLNIEGTEKGNCGRDRQNWIQCSKQDVLCGYLLCSNISGIPQIGELNGDITSMSFYHQNRYLDCRGGQVTLPDGSCLGYVEDGTPCGPNMICLDRRCLPASAFNFSTCPGSWNGVICSDHGVCSNEGKCICHPEWTGKDCSVYDPLPVPKPTGVVEKYKGPSGTNIIIGSIAGAVLIAAIVLGGTGWGFKNIRRGRSGGG
What is the function of this protein?
Probable ligand for integrin in the brain.  This is a non-catalytic metalloprotease-like protein.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 11, ADAM 11, MDC11.1, Metalloprotease-disintegrin MDC11a, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein, MDC.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y778_ACTSZ
Sequence: MAKNSKYSDKQVDAVLHDMIAVLEKHQAPVELSLIVLGNMVTNLLASSVGTHQQAALAQAFSDALMNSVKK
What are the official names of this protein?
UPF0352 protein Asuc_0778.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: GRDE_PEPAC
Sequence: MRLEIGNIFIKDIQFGEQTKVENGVLYVNKDEMIKKLSVIEHIKSVDLDIARPGESVRITPVKDVIEPRVKVEGPGGIFPGVISKVETDGSGRTHVLKGAAVVTTGKVVGFQEGIVDMSGVGAEYTPFSKTLNLVVIAEPEDGIEQHRHEEVLRMVGLNAGVYIGEAGRSVTPDEVKVYETDTIFEGAAKYPNLPKVGYVYMLQTQGLLHDTYVYGVDAKKIVPTILYPTEVMDGAILSGNCVSSCDKNPTYVHCNNPMVEELYAMHGKEINFVGVIITNENVYLADKERSSDWTAKLCKFLGLDGAIVSQEGFGNPDTDLIMNCKKIEMEGVKTVISTDEYAGRDGASQSLADADVRANAVVSNGNANMVIVLPPMDKTIGHIQYIDTIAGGFDGSLRADGSIEVEIQAITGATNELGFGYLSAKGY
What is the function of this protein?
In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate.  Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine.  By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state.  Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
What are the official names of this protein?
Glycine reductase complex component B subunits alpha and beta, Selenoprotein PB alpha/beta.
Protein: GPMI_YERPN
Sequence: MSSTKKPLVLTILDGYGHREEQQDNAILNAKTPVMDVLWQQQPHTLIAASGLDVGLPDGQMGNSEVGHVNLGAGRIVYQDLTRLDKEIKEGDFFTNPTLTAAVDNAVKTGKAVHIMGLLSAGGVHSHEDHIMAMVELAAKRGATAIYLHAFLDGRDTPPRSAESSLKRFTAKFAELGNGRIASIIGRYYAMDRDNRWDRVQLAYDLLTQAKGEFTADNAVAGLQAAYARGENDEFVKPTVIQATGEADAAMNEGDTLIFMNFRADRARQITRTFVNAEFDGFKRDKVVNFGDFIMLTEYAADIKVACAYPPASLTNTFGEWLMKHDKTQLRISETEKYAHVTFFYNGGVEEPFKGEDRILINSPKVATYDLQPEMSSAELTEKLVSAIGSGKYDVIICNYPNGDMVGHTGDYDAAVKAVETLDNCIEQVVAAVKAADGQLLITADHGNAEQMRDPATGQAHTAHTSLPVPLIYVGNKAVKAVEGGKLSDIAPTMLSLMEMEIPQEMTGKPLFIVE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RF1_LEIXX
Sequence: MFDSVTGLIAEHDDLQQQLSDPELHSDPVRSKKVNRRYAELSRIVAAYTEWKQLTDDLEAARELAAEDDAFAAEIPGLEQGLEESEEKLRRLLIPRDPNDSRDAIMEIKMGEGGAESALFAGDLLSMYLHYADSRRWKAEIIEQTSSDLGGIKDVQVAFKGSSSDPAEGVWAHLKYEGGVHRVQRVPATESQGRIHTSAAGVLVFPEVDEPEEVEINPNDLKIDVFRSSGPGGQSVNTTDSAVRITHAPTGIVVSMQNEKSQLQNREAAMRVLRARLLAKQQEEADAEAAEFRKGQIRTMERSERIRTYNFPENRIADHRTGYKAYNLDAVMNGALGPVIESCILADEETRLANLSTD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SVP1_CAVPO
Sequence: MKSTIFFILSLLLMLENQAAGRRLSGSAGAQDPVISRVWAKSQDMEEAVSGSGLTAEGGRGSDREESVGERVSLRQEEFEKGHIRSSVEEPEGEHVSVRREHLEKSHIRHNVEEPEGERVSVRREHLEKSHIRHSAEEPEGERVSVRHERVEKTHKRFHDDSVEESDSASSVDHRKKGHIRFKRQDPIAALAAIEGQDAVKDSLWVKGQASSEERFSVKGQDLVKGHLQMKGQSSLAERFSVTGQDSVKGRLQMKGQDTLAERFSMTGQDSVKSRLQMKGQDSLSERFSMTGQDSVKGRLQMKGQSSLAERFSVTGQDSVKGRLQMKGKDTLAERFSVTGQDSVKGRLQMKGHDLLEERFSVSGQDSVKGLARIKGQESVQSGFSVKGQGSLKGLI
What is the function of this protein?
SVP-1 serves as substrate in the formation of the copulatory plug.  SVP-3 and SVP-4 may also contribute to the clot.
What are the official names of this protein?
Seminal vesicle major clotting proteins.
What is the protein family that this protein belongs to?
To the SVP-2 precursor, particularly in regions where protein processing must occur.
What are the subcellular locations of this protein?
Secreted.
Protein: NU2C2_ATRBE
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVLIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDSLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.