PharMolix/UniProtQA huggingface dataset:
Protein: MZM1_BOTFB
Sequence: MALAAYRHLLRATRVAFNVEDITLLTSARKQARSTFLANRSLALESPESIAAIAHAEDVAQFLRRNVVQGQKVEGDEKYKLNIHEHTERGDNDTIKMPNGKNVTIDGKTCKD
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SPEE_HYDS0
Sequence: MKDVYFMERDPYAPIRHCYGISKILYEGKSKYQEIQVVESHYFGKILILDGVVQFTEKNEFFYHEMLTHPVMFAHKNPQNVLIIGGGDGGILREVLKHKSVKKAVLVDIDKDVVEVSKKFFPTVACSMDDPRAIILNEDGFKYIQDYKNEFDVIIVDSTDPVGFAHVLTTEEFFKYVFEALKEDGIYVGQSESLHYHLDIVVRFQKALKKSFPIVDLYTTVIPVYAGYWWSFSVGSKVYNPREISREVDVETRFYSDEIHKNAFLPPNFYQKILNGNFKY
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDIP_ECOLI
Sequence: MYQRCFDNASETLFVAGKTPRLSRFAFSDDPKWESGHHVHDNETELIYVKKGVARFTIDSSLYVAHADDIVVIERGRLHAVASDVNDPATTCTCALYGFQFQGAEENQLLQPHSCPVIAAGQGKEVIKTLFNELSVILPQSKNSQTSSLWDAFAYTLAILYYENFKNAYRSEQGYIKKDVLIKDILFYLNNNYREKITLEQLSKKFRASVSYICHEFTKEYRISPINYVIQRRMTEAKWSLTNTELSQAEISWRVGYENVDHFAKLFLRHVGCSPSDYRRQFKNCFAEQEILSEFPQPVSLVG
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YdiP.
Protein: IXTPA_ACHLI
Sequence: MDIIFASNNYHKFIEMESILKPHQITLLKDFQIDEKEIIESGLTFEANAQIKARAFAKRFNQVAIADDSGIIIEAISPLPGIYSKRYSGLGDTVNNIKVLDVLKNKENRQARFVCAIAIAFPDGKIFTYVGNMLGNIALNLKGSMGFGYDPIFIPDGKQETLGELGSTYKDEHSHRRHALNNFLEAKDEIIDYWRYTWKK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: MIAA_MYCPA
Sequence: MTAAVRPLPIIGPTGTGKSQLALDVAERLGPLGAEIVNADAMQLYRGMDIGTAKLPVDARRGIPHHQLDVLDVTQTATVARYQRAAAADIEAILAAGAVPIIVGGSMLYIQSLLDDWSFPATDPRVRARWERRLGEVGVGELHAELARRDPAAAAAILPTDARRTVRALEVIELTGRPFAASAPRIGAPRWDTVIIGLDCDTTLLDERLARRTDAMFEQGLVAEVTGLLGRGLRDGVTAARALGYAQVIAALDAGGGDEQLRQAREQTYAGTRRYVRRQRSWFRRDHRVRWLDAGACSPPRLADAALEAWRHVS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CYSC_RHOBA
Sequence: MSQSNSDDSASSSTQQAGDGQDDVQQNIVWHAHTVSREDRESKLGQRGVVVWFTGLSGCGKSTIANELDRLLIDRGATCTLLDGDNVRHGLCAPPSVLKEEHGEDFAGRFGLGFGPTDREENIRRIGAVTELFASAGVIVLAAFVSPYQRDRDRVRNTIESSGRAGDFLEVFVDTPLEICKQRDPKGLYQKAIAGEIKNFTGISDPYDAPPSPEIHLKWREGQTPHDQASEIIREMEKRGVLGPAKG
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: YO015_YEAST
Sequence: MPHFKRAAVYEEQKRTGKWGQLVEETKDRIPEYSNKTIAKISHLDNGCLWPEIKVSFSHHLSILQSMCLHFIISILFSKYIFVFLFAFLLPSAFPLFILHSTLFRKPCLSIIGFLKTKV
What are the official names of this protein?
Uncharacterized protein YOR015W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYA_LEPBJ
Sequence: MKRQSVSEIREIFLNYFKDKAHAVVPSSSLLPAGDPTLLFTTAGMVQFKPLFTGAVELPYTRATSCQKCLRTTDLEVVGKTERHCTFFEMLGNFSFGDYFKEEAIDYALDCSVNHLGFDKEKIWVTVYTDDDEAEKIWITKGIPKERITRLGKKDNFWGPAGDSGACGPCSELYLDRGVEKGGPDCATSGTCRPGCDCDRFLEFWNIVFNQFNQDTEGNLHPLKQTGIDTGSGLERVALLLQGADSVYDTNELRKIISFYEELSGIKYDDVITLSKMPTQKNNTARIAANQKAAFRVVTDHIRSVLFSIGDGIYPDRTGRGYVIRRLIRRATLFGRKLNFKEPFLYKLVDKVVEIYKPRYPELGKNSAAIQKTILAEEELFLKTLELGLEKIETLVAKTKTSGKTIFSGADAFLLYGTYGFPAEMTEEIVAEQGLDFDKKGFQEELEKDRQLSRESWKANKVSLMTGQSVEKTEFLGYSSLSGKGNIIHLFNENKPAGALKEGQAGAIVLNKTPFYPEGGGQVGDTGFLRQGKNVFKVLDTQKENDVILHFGEVLSGEFSIAQELEAEVEAARRERLRFHHSGTHLLNGALRNLLGDHVLQKGSVVSPEYLRFDFSHPSALTSKEIRKIESWVNESIRKNYPVVTKELPIEDAKKIGAVATFGEKYGDRVRVVQMGDASVEFCGGTHVSHTGEIGYFFIKKESSPGAGNRRIEGVCGPAVIETFQNRFAELTESVQNLNLKIKSELDNEGSKILVNSNVPGPDEIREKLEKEGATAVTFFRDLSEEIASQIEESTSAFLKMKKSLESRDFENNASVIEKVFASSMDTGVGKIVSAIFDDKDPNSLKGLSDNLKVREKNLLVILGSKNADNASVVITCSSQLVSKGIHCGDLVRTVCEMLGGKGGGKPDMAQGGGKEKQNLESAISFAIQLAKQTLTGEKV
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAP1_NPVAC
Sequence: MNEDTPPFYFISVCDNFRDNTAEHVFDMLIERHSSFENYPIENTAFINSLIVNGFKYNQVDDHVVCEYCEAEIKNWSEDECIEYAHVTLSPYCAYANKIAERESFGDNITINAVLVKEGKPKCVYRCMSNLQSRMDTFVNFWPAALRDMITNIAEAGLFYTGRGDETVCFFCDCCVRDWHTNEDTWQRHAAENPQCYFVLSVKGKEFCQNSITVTHVDKRDDDNLNENADDIEEKYECKVCLERQRDAVLMPCRHFCVCVQCYFGLDQKCPTCRQDVTDFIKIFVV
What is the function of this protein?
Acts by blocking cellular apoptosis early in infection.  Later, stimulates caspase-3-like protease activity and induces apoptosis, probably to favor the release of occluded virions.
What are the official names of this protein?
Apoptosis inhibitor 1, IAP-1.
Protein: IL2RB_RAT
Sequence: MATVDLSWRLPLYILLLLLATTWVSAAVNDCSHLKCFYNSRANVSCMWSPEEALNVTSCHIHAKSDMRHWNKTCELTPVRQASWACNLILGPLPDSQSLTSVDLLSLSVVCWEEKGWRRVKTCTFHPFDNLRLIAPHSLQVLHIETRRCNISWEVSQVSHYVNPYLEFEARRRLLDRSWEDASVFSLKQRQQWIFLETLTPDTSYELQVRVIAQRGKTRTWSPWSQPMAFRTRPADPKEIFPLPWLRCLLLVLGCFFGFLSCVCVLVKCRYLGPWLKTLLKCHIPDPSEFFSQLSSQHGGDLQKWLSSPVPQSFFSPTGSAPEISPLEVLDRDSKTMQMLLFQKEKASSPSPSGHSQASCFTNQGYFFFHLSNALEIESCQVYFTYDPCMEEDVEEDGPRLPEESPLPPLLPFTGEQDDYCAFPPRDDLLLFSPSMSTPNTAYGNSITPEERPPLSLQEGLPSLASPDLMGLQHPLELELGDDGEGMSTNSSGQQASVPEAALMGTTKTEARPVLTLNTDAYLSLQELQAQDSAHLI
What is the function of this protein?
Receptor for interleukin-2.  This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.  Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity).
What are the official names of this protein?
Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell surface.
Protein: 3SO92_BUNCA
Sequence: MKTLLLTLVVLTIACLDLGYTKTCFNDNLANPKTTELCRHSMYFCFKNSWIAGGVERIERGCSLTCPDIKYNGKYIYCCTRDNCNA
What are the official names of this protein?
Candiduxin-2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group IX sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTNN_STAAS
Sequence: MIGIIGAMEEEVTILKNKLTQLSEISVAHVKFYTGILKDREVVITQSGIGKVNAAISTTLLINKFKPDVIINTGSAGALDESLNVGDVLISDDVKYHDADATAFGYEYGQIPQMPVAFQSSKPLIEKVSQVVQQQQLTAKVGLIVSGDSFIGSVEQRQKIKKAFPNAMAVEMEATAIAQTCYQFNVPFVVVRAVSDLANGEAEMSFEAFLEKAAVSSSQTVEALVSQL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: TOLB_BORA1
Sequence: MPTMTPAFSRASLSEALRSYGLALLLFLATLLAWQPAHAQLRVDISGTGATQYPIAIADFAGDDVRGRALAEVIRADLTRTGQFRLINAAGSGLTVDSPINYDDWRGRGADYVAYGSISQGADGRFEIRYRLADTVKKNQLDGVAFSGTEPELRRIAHQIADRIYEKITGVRGVFATRIAYVLKQGNTYELQVADADGQNPQVALRSREPIISPTWSPDGSKLAYVSFHSGKPVVYVQTLATRSQIPVANFKGNNSAPAWSPDGSQLAVALTQDGLSQIYIVSADGSAKPRRITRSPGIDTEPTFTPDGRSIIFTSDRSGGPQIYQVGLDGGDARRLTFNGSYNISPRISPDGSTLLYVARRDGAFRIASLNLPTGTETLLTDGRDDQSPSFAPNGMQVLYAATQNGRSVLAGVSSDGRVRQTLSVLNGEIREPTWGPFTR
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: BIOB_NOSP7
Sequence: MVGIRYDWQELEIRAIYNTPLLELIYQAASVHRQYHDPTKIQVCKLISIKTGGCPEDCSYCAQSSRYKTEVKAEALLEKETVVNIAQKAKETGVSRICMGAAWREVRDNSQFEEVLEMVKDITAMGLEVCCTLGMLTANQARKLEEAGLYAYNHNLDTSQEYYSTIITTRTYSDRLNTIENVRQTNVTVCSGGILGLGETVDDRVGMLQTLANLHPHPESVPINILSQVPGTPLENQPDVPIWDIVRMIATARILMPASDVRLSAGRARLSQVEQAFCFMAGANSIFSSDDNKMLTVTTPCPDYDTDREMLNLLGLGMRPPSQRQEKVASPAVVG
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RASA2_HUMAN
Sequence: MAAAAPAAAAASSEAPAASATAEPEAGDQDSREVRVLQSLRGKICEAKNLLPYLGPHKMRDCFCTINLDQEEVYRTQVVEKSLSPFFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCNHSGKETWFSLQPVDSNSEVQGKVHLELKLNELITENGTVCQQLVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEIFYFEVTRSSSYTRKSQFQVEEEDIEKLEIRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLNICYTEDYVLPSEYYGPLKTLLLKSPDVQPISASAAYILSEICRDKNDAVLPLVRLLLHHDKLVPFATAVAELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICDSSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQRFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGSWGSLSKSKSSFKETFMCEFFKMFQEEGYIIAVKKFLDEISSTETKESSGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTYHKQPGSKDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHTEKPLYVQANNCVEANEWIDVLCRVSRCNQNRLSFYHPSVYLNGNWLCCQETGENTLGCKPCTAGVPADIQIDIDEDRETERIYSLFTLSLLKLQKMEEACGTIAVYQGPQKEPDDYSNFVIEDSVTTFKTIQQIKSIIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKAS
What is the function of this protein?
Inhibitory regulator of the Ras-cyclic AMP pathway.  Binds inositol tetrakisphosphate (IP4).
What are the official names of this protein?
Ras GTPase-activating protein 2, GTPase-activating protein 1m, GAP1m.
Protein: COFG_METTP
Sequence: MCAGIQAEARGAEALRATFSRNVFIPVTDLCRNACGYCSFRRDPDRARVISRSEAQRLMERAQSAGCSEALFSMGDRPWEVRGDRLELLEYLVELCELALEMGLLPHTNAGILTREELELLAPYNASMGLMLESTAHLKIHERSPGKRPEVRIRTISDAGALRIPFTTGILVGIGESSEDRIRSLEVIAELHRRYGHIQEVIIQPLDPKPGTESEGMHPPAMTDMVKLVSIARRILPLEISIQVPPNLMDPVPLLRAGADDLGGISPVTPDWINPERRWPEIDELRGVVLVERLPVYPRYVKLGWYGSRTKDLIKRLADERGLRRT
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: GSHB_YEAST
Sequence: MAHYPPSKDQLNELIQEVNQWAITNGLSMYPPKFEENPSNASVSPVTIYPTPIPRKCFDEAVQIQPVFNELYARITQDMAQPDSYLHKTTEALALSDSEFTGKLWSLYLATLKSAQYKKQNFRLGIFRSDYLIDKKKGTEQIKQVEFNTVSVSFAGLSEKVDRLHSYLNRANKYDPKGPIYNDQNMVISDSGYLLSKALAKAVESYKSQQSSSTTSDPIVAFIVQRNERNVFDQKVLELNLLEKFGTKSVRLTFDDVNDKLFIDDKTGKLFIRDTEQEIAVVYYRTGYTTTDYTSEKDWEARLFLEKSFAIKAPDLLTQLSGSKKIQQLLTDEGVLGKYISDAEKKSSLLKTFVKIYPLDDTKLGREGKRLALSEPSKYVLKPQREGGGNNVYKENIPNFLKGIEERHWDAYILMELIEPELNENNIILRDNKSYNEPIISELGIYGCVLFNDEQVLSNEFSGSLLRSKFNTSNEGGVAAGFGCLDSIILY
What are the official names of this protein?
Glutathione synthetase GSH2, GSH synthetase, GSH-S, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic GSH synthase family.
Protein: PUR9_PSEP1
Sequence: MTDQTTRLPVRRALISVSDKTGILEFARELQQLGVEILSTGGTYKLLKDNGVNAVEVADYTGFAEMMDGRVKTLHPKIHGGILGRRGTDDAIMNEHGIKPIDLVAVNLYPFEATISKPGCDLPTAIENIDIGGPTMVRSAAKNHKDVAIVVNASDYAGIVEGLKAGGLTYAQRFDLMLKAFEHTAAYDGMIANYMGTIDQAKDTLSTEARSEFPRTFNSQFVKAQEMRYGENPHQSAAFYVEAKKGEASISTAVQLQGKELSFNNVADTDAALECVKSFVKPACVIVKHANPCGVAVVPEDEGGIRKAYDLAYATDTESAFGGIIAFNRELDGETAKAIVDRQFVEVIIAPKISQAARDVVAAKQNVRLLECGEWPAERAAGWDFKRVNGGLLVQSRDIGMITADDLKIVTKRAPTEQEIHDLVFAWKVAKFVKSNAIVYAKQRQTIGVGAGQMSRVNSARIAAIKAEHAGLQVQGAVMASDAFFPFRDGIDNAAKVGISAVIQPGGSMRDAEVIAAADEAGIAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: MOAC_PHOPR
Sequence: MMNQLTHINASGEANMVDVSAKAETVREARAEAFVHMAPETLELIVSGQNHKGDVFATARIAGIQAAKKTWDLIPLCHPLLLSKVEVQLEAIPAANENETNMVRIESCCKLAGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKTGGKSGHFKVEA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: ETR2_ARATH
Sequence: MVKEIASWLLILSMVVFVSPVLAINGGGYPRCNCEDEGNSFWSTENILETQRVSDFLIAVAYFSIPIELLYFVSCSNVPFKWVLFEFIAFIVLCGMTHLLHGWTYSAHPFRLMMAFTVFKMLTALVSCATAITLITLIPLLLKVKVREFMLKKKAHELGREVGLILIKKETGFHVRMLTQEIRKSLDRHTILYTTLVELSKTLGLQNCAVWMPNDGGTEMDLTHELRGRGGYGGCSVSMEDLDVVRIRESDEVNVLSVDSSIARASGGGGDVSEIGAVAAIRMPMLRVSDFNGELSYAILVCVLPGGTPRDWTYQEIEIVKVVADQVTVALDHAAVLEESQLMREKLAEQNRALQMAKRDALRASQARNAFQKTMSEGMRRPMHSILGLLSMIQDEKLSDEQKMIVDTMVKTGNVMSNLVGDSMDVPDGRFGTEMKPFSLHRTIHEAACMARCLCLCNGIRFLVDAEKSLPDNVVGDERRVFQVILHIVGSLVKPRKRQEGSSLMFKVLKERGSLDRSDHRWAAWRSPASSADGDVYIRFEMNVENDDSSSQSFASVSSRDQEVGDVRFSGGYGLGQDLSFGVCKKVVQLIHGNISVVPGSDGSPETMSLLLRFRRRPSISVHGSSESPAPDHHAHPHSNSLLRGLQVLLVDTNDSNRAVTRKLLEKLGCDVTAVSSGFDCLTAIAPGSSSPSTSFQVVVLDLQMAEMDGYEVAMRIRSRSWPLIVATTVSLDEEMWDKCAQIGINGVVRKPVVLRAMESELRRVLLQADQLL
What is the function of this protein?
Ethylene receptor related to bacterial two-component regulators.  Acts as a redundant negative regulator of ethylene signaling.
What are the official names of this protein?
Ethylene receptor 2, AtETR2, Protein ETHYLENE RESPONSE 2, Protein ETR2.
What is the protein family that this protein belongs to?
Belongs to the ethylene receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PURA_MOOTA
Sequence: MAAVVLVGAQWGDEGKGKITDYLAERADVVIRYQGGSNAGHTVMVGHEEFKLHLVPSGILYPGKLCIIGNGVVLDPAVLVEELDGLAARGVDTSGLKISNRAHLILPYHKGLDAAEEEHRGAAMIGTTKRGIGPAYVDKAARTGIRVGDLLDWEEFSAKVAHNLAATNELLAKIYDRPGYDLQAILEEYAGYARRLRPLIADSVRLVNRALQEGRKVLFEGAQGTLLDLDQGTYPFVTSSYPVAGGACIGAGVGPTRIDKVIGVVKAYTTRVGSGPFPTEITGPAGDALRQQGMEFGTTTGRPRRCGWLDTVILRHAAEVNGLTGIALTKLDVLTGLDPLRICTSYRYRGTVGEDFPASLKALEECEPVYEELPGWHEDITGARSLDDLPANCRRYIRRLEELTGVPVHLIAVGPRRDQTIVLESPF
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG8_KLULA
Sequence: MKSAFKSEFPFEKRKAESERIVQKFHNRIPVICERGGKSDIPDIDKRKYLVPGDLTVGQFVYVIRKRIKLPAEKAIFIFVNDTLPPTAALMSSIYQQHKDKDGFLYVSYSSENTFGDDALFSEE
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Participates also in membrane fusion events that take place in the early secretory pathway.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Protein: RNPA_BLOPB
Sequence: MNRKFLPKRARLLNLNEFIFVFQKPERVKTTGITLFSRSNRLGYPRIGLAISKKYVKYAHERNRIKRHIRETFRTCQHNLLAKDFVLTIRSKEIIYYKNKTLIQELEKLWYHHLC
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: SEPF_SYNPW
Sequence: MSLISRLRAVVAGDDYLDGDYDDLDYDAGEHDDSPQAMASASSALAPLDAANPFDMDQGFSGSNVIGMPGISSSAAEVSLMEPRSFDEMPRAIQALRERKTVILNLTMMEPDQAQRAVDFVAGGTFAIDGHQERVGESIFLFAPSCVTVTNSAHEEASTPTVVTKDVEQASAEASVAPAPAWAAPGAAAL
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: Y1571_ARCFU
Sequence: MQKKVLSLVLVLAVLESIVPVSAWGTITHVRMSSEAGNPYTGFKMEYLSGSIAPDAGYIISTEWGTKFHGYYVNDALNIANKMLSLAEGTDEKAFAKGWLAHLMQDRVAHGNGDGLPKDQAYGEGYSNYAAKKYGLTHIEAEFFVNGRVIHEKGWDWDFVRFAVPTELIVKTMRSLYGSAPNENDLNNAYNTFAMEYYGELAFWNSPSGNTAYLTLLLFGTVSDYDDYVSDVHCNPYEESIYLTNHPNARSTYAAGTYIMGVKKVKSSDGQIKKWMKEYAERLEKAGAIKVNRKFEDGWLVIEFRMVDKYKADRIAKEVLQDMARSEEIFQFINLKGDEK
What are the official names of this protein?
Uncharacterized protein AF_1571.
Protein: RS18_UREPA
Sequence: MAKVTNNRNRKPRKKVCILSAKGIEHVDYKDVELLQRFINNNNKIASRRVTGASARMQRRIANAIKRARFVGLLPYVKE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PYRG_PYRAE
Sequence: MPKLIIVTGGVMSGVGKGVVVASIGRILRARGLSVNAVKIDPYINVDAGTMNPYAHGEVFVTYDGGETDLDLGHYERFLDVELSKRNNITSGQIYLTVIEKERRGEYLGQTVQLIPHVTDEIKRRIVEASGGYDVTLVEIGGTVGDYEQLPFLEAARQLGLELGEDVVFIHVAWVPLLKITGEFKTKPLQHSVAELRRYGIQPDAVVVRSEKPIDANSIKKIALFAHVPQWAIFNSYDVDTIYRVPLILEQQGLGDFLTRRLRLPSRSPEYRDWEEFLSKLSAPKYRISVGMCGKYVELPDAYLSIVEALKHAGAALDARPELVWINSVEVEKNPDILRKLDLDAIVVLPGFGKRGTEGMIECIRHARMEKIPFLGICFGMQLAVVEFARNVLGLKGANSTELDPETPHPVVHLAPEQREVDVLGGSMILGNREVEIVPGTLAASLYGVSVITERHRHRYEVNLSYLPKFTEAGLVVSGWRRDIKRVEIIELPGHPYFIATQFHPEFKSRPAKPRPVFLGLLKAALFAKR
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RL29_PHEZH
Sequence: MKIDEVRGMTPDQLNEQLVALKKEQFNLRFQKATGQIEKTHRVDEVRKDIARIKTVLRAKQAQA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RLMI_ECOK1
Sequence: MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVDHQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFTRRLQQAQKWRDWLAQKDGLDSYRLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECAIYDRSDVAVRKKEGMELTQGPITGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRYVENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSHEALDIARQNVELNKLDLSKAEFVRDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPK1_LOCMI
Sequence: QDSGDGWPQQPFVPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Locustapyrokinin-1, Lom-PK-1.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.