PharMolix/UniProtQA huggingface dataset:
Protein: CEL3A_XENLA
Sequence: MKEPDAIKLFIGQIPRNLDEKDLKPIFEQFGKIYELTVIKDKFTGMHKGCAFLTYCARESALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRRMFEPFGNIDECTVLRGPDGTSKGCAFVKFQTHTEAQAAINALHGSRTLPGASSSLVVKFADTEKERGLRRMQQVANQLGMFSPIALQFGAYSAYTQAVSDQLMQQQAALVAAHSAYLNPMATMAAVQMQQMATINPNGIIATPITQINPITSSSGTSTPPTLTATQVSAIPATLGVNGYSAVPTQSTVQPSSEAIYTNGLHPYPAQSPVAQLDPLQQAYAGMQHYTAAYPAAYGLVSPAFTQPPAILQQQPPQQQQQREGPEGCNIFIYHLPQEFTDSEILQMFLPFGNVISAKVFVDRATNQSKCFGFVSFDNPGSAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY
What is the function of this protein?
RNA-binding protein that may be involved in the regulation of pre-mRNA alternative splicing.
What are the official names of this protein?
CUGBP Elav-like family member 3-A, CELF-3A, Bruno-like protein 1-A, CUG-BP- and ETR-3-like factor 3-A, ELAV-type RNA-binding protein 1-A, ETR-1-A, RNA-binding protein BRUNOL-1-A, Trinucleotide repeat-containing gene 4 protein A.
What is the protein family that this protein belongs to?
Belongs to the CELF/BRUNOL family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ATPE_STRP7
Sequence: MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAVLAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLRAERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KHSE_GLUOX
Sequence: MAVYTELAAETLEAFLGTYDIGTLVSFHGIAEGVENSNFLLRTTEGDFILTLFERRVNARELPWFLGLMQYLAGRGLNCPLPVSDRSGTALRSLADRPAAITTFLPGVSATQLDANLCLELGKVLARLHIAGEGYDAVRPNALSPAAWGPLLDSCGESGDELSPGLTAEVRKALQNVEAAWPATADLPRGQIHADLFPDNVFFQNGQVSGLIDFYFACTDFLAYDLAICLNAWCFRDEKTFEPSFAAAIMQGYESVRPLSDAEKAALPTLCQGAAIRFLLTRLYDWINTPADALVTRKDPLAYLRRLRHFQSASHV
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: PP234_ARATH
Sequence: MYSLSRILQRSQRYNFAPSSFGAVSKLEVSSGGDKERVFKSFGLIYSKPQGLVRLYSARDVFSRFFGIHKLSSIADAKDKGDEVVREEELSESEEAVPVSGDVPEGVVDDDSLFEPELGSDNDDLEIEEKHSKDGGKPTKKRGQSELYESIVAYKSVKHVLEKWVKEGKDLSQAEVTLAIHNLRKRKSYAMCLQLWEWLGANTQFEFTEANYASQLDLVAKVHSLQKAEIFLKDIPESSRGEVVYRTLLANCVLKHHVNKAEDIFNKMKELKFPTSVFACNQLLLLYSMHDRKKISDVLLLMERENIKPSRATYHFLINSKGLAGDITGMEKIVETIKEEGIELDPELQSILAKYYIRAGLKERAQDLMKEIEGKGLQQTPWVCRSLLPLYADIGDSDNVRRLSRFVDQNPRYDNCISAIKAWGKLKEVEEAEAVFERLVEKYKIFPMMPYFALMEIYTENKMLAKGRDLVKRMGNAGIAIGPSTWHALVKLYIKAGEVGKAELILNRATKDNKMRPMFTTYMAILEEYAKRGDVHNTEKVFMKMKRASYAAQLMQYETVLLAYINAKTPAYGMIERMKADNVFPNKSLAAKLAQVNPFKKCPVSVLLDI
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g15590, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GUAAB_PYRHO
Sequence: MDWGRFVEEKVREIRETVGDSKAIIALSGGVDSSTAAVLAHKAIGDRLHAVFVNTGFLRKGEPEFVVKTFRDEFGMNLHYVDAQDRFFSALKGVTDPEEKRKIIGRVFIEVFEEVAKKIGAEYLIQGTIAPDWIESQGKIKSHHNVGGLPEKLNLKLIEPLRDLYKDEVRELAKFLGLPEKIYNRMPFPGPGLAVRVIGEVTPEKIRIVREANAIVEEEVERAGLRPWQAFAVLLGVKTVGVQGDIRAYKETIAVRIVESIDGMTANAMNVPWEVLQRIAFRITSEIPEVGRVLYDITNKPPATIEFE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: UL140_HCMVM
Sequence: MTPAQTNGTTTVHPHGAKNGSGGSALPTLVVFGFIVTLLFFLFMLYFWNNDVFRKLLRCAWIQRCCDRFDAWQDEVIYRRPSRRSQSDDESRTNSVSSYVLLSPASDGGFDNPALTEAVDSVDDWATTSVFYATSDETADTERRDSQQLLIELPPEPLPPDVVAAMQKAVKRAVQNALRHSHDSWQLHQTL
What are the official names of this protein?
Protein UL140.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: ADIRF_HUMAN
Sequence: MASKGLQDLKQQVEGTAQEAVSAAGAAAQQVVDQATEAGQKAMDQLAKTTQETIDKTANQASDTFSGIGKKFGLLK
What is the function of this protein?
Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation.  Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin.
What are the official names of this protein?
Adipogenesis regulatory factor, Adipogenesis factor rich in obesity, Adipose most abundant gene transcript 2 protein, Adipose-specific protein 2, apM-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTNA_HAHCH
Sequence: MSQSSVSAIRWANNQLILLDQRKLPLQEAYVNCVTHVEVADAIRQMVVRGAPAIGIAAAYGVALAAAEFGSDRDRLHRALETLADSRPTAVNLFWALRRMRGLIDGASVADLFPLLVEEATRIHEEDLQANLTMGELGADLIAESGRGALLTHCNTGSLATGGYGTALGVIRSAYRRDLVTEVFADETRPWLQGARLTAWELCQDDIPVKLIADSAAAHVMKTCAVKWVIVGADRITAHGDVANKIGTYGLAVLARHHGVKFMVAAPSSTIDFELFSGADIPIEERTSDELKFVQGTPLAPEKADAFNPVFDVTPAELIDAIVTERGVVLRPNAEKMLKLQ
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: ECFA1_MYCGA
Sequence: MDNKNSVIKFENVSFSYNSKKQVLKNVSYEIYEKEYVCIVGHNGSGKSTMSKLLTGILKPLAGTIYLFGYAISRDNIKFLRDNVGIIFQNPDNQFIGITAEDDIAFGLENRKIPRGEIKRIIDSVADKVGIKDILKFEPHKLSGGQKQRVAIASVLAINPSIILFDESTSMLDPKGKKDIKSFMLQLRNQGKTVISITHDMEEVVNCDRVLVMDHGNLIKQGRPDEIFKDKQFLRDINLDVPFSLDLAMQLNELDEKINSTLRYNELIDNICSRVDQKD
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RSMA_NEIG1
Sequence: MKEHKARKRFGQNFLQDTRIIGDIVNAVRPQADDVVIEIGPGLAAITEPLAKKLNRLHVVEIDRDIVCRLKTLPFADKLVIHEGDVLQFDFNGISGKKKIVGNLPYNISTPLLFKLAEVADDVADMHFMLQKEVVERMVAAPKSNDYGRLGVMLQYFFDMELLIDVPPESFDPAPKIDSAVVRMIPVKHRIGKADDFDHFAKLVKLAFRQRRKTIRNNLKELADDDDLQAVGISPQDRAEHIAPEKYVALSNYLADKAV
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_STRPG
Sequence: MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYLLIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQKLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHTSH
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: NCPP_SHESR
Sequence: MQQNIIKVIVGSKNPVKINAAANAMALLFPEYEIQTQGMDAPSGVPAQPMTDSDTRQGAINRVHYCQQQVEADYYFAMEGGVDCFEFGPATFAYIAIAHQARLSIGRGALLPLPMQVYQALEAGEELGHVMDRLFNTVNIKQKGGAIGLLTHGHATRESNYTQAIILAMAPFLNPELYP
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: NDK_MYCTO
Sequence: MTERTLVLIKPDGIERQLIGEIISRIERKGLTIAALQLRTVSAELASQHYAEHEGKPFFGSLLEFITSGPVVAAIVEGTRAIAAVRQLAGGTDPVQAAAPGTIRGDFALETQFNLVHGSDSAESAQREIALWFPGA
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_BRUAB
Sequence: MEGIFAAYVLPALIIALKSVVLLVVLLIVVAYLLYADRKIWAAVQLRRGPNVVGPWGLFQAFADLLKFVFKEPIIPSGANKGVFLLAPFISAVLAMATWAVIPVNEGWAVANINVGILYIFAISSLEVYGVIMGGWASNSKYPFLGALRSAAQMVSYEVSIGFVIVTVLLTVGSLNLTDIVLSQNTGLGTMLGLPASFLDWNWLCLFPMFVVFFISALAETNRPPFDLVEAESELVAGHMIEYSSTPFLLFFLGEYVAITLMCALMTVLFLGGWLPPVDVWFLSWVPGIIWFMLKLCFCFFLFAMVKAFVPRYRYDQLMRLGWKVFLPISLFMVVATATFLKVFGLA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y6590_MYCAP
Sequence: MAGHSHWAGIKHKKGANDAARGKIFQKMFKEIYVAATGPGGTDPSSNPALRLAISKAKAKSMPKANIERALDKAKGNAKDGAVFTEIIYNATISGGATFLVITLSDNVNRTTSNIQSYFNKQNAKLGKTGTIPFQFDHKGIMEISKSLVDEESLTIVCLENGAEDIEATDESFIITTSVEDFSTCKSAIESNLNITEFMQCEITYLPNATVTFTGEKAQKIQDFIAKLEDDDDVQEVFHNIEFEE
What are the official names of this protein?
Probable transcriptional regulatory protein MAG6590.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_THET2
Sequence: MALKDLFERDVQELEREGILFTTLEKLVAWGRSNSLWPATFGLACCAIEMMASTDARNDLARFGSEVFRASPRQADVMIVAGRLSKKMAPVMRRVWEQMPDPKWVISMGACASSGGMFNNYAIVQNVDSVVPVDVYVPGCPPRPEALIYAVMQLQKKVRGQAYNERGERLPPVAAWKRTRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYL_FLAJ1
Sequence: MKYNPNEIEAKWQKYWAENQTFAAKNNSEKPKHYVLDMFPYPSGAGLHVGHPLGYIASDVYSRFKRHQGFNVLHPMGYDSFGLPAEQYAIQTGQRPEDTTRVNIDGGVDKEGKQIAGYRKQLDKIGFSFDWAREVRTSNPDYYKHTQWIFIQLFNSWYCRKQGKAFDISELVTVFEESGNALVEAVCDDNVTIFTADEWKSYSDDQKEKILLQYRMTYLAETEVNWCPGLGTVLANDEIVNGVSERGGFPVIRKKMTQWSMRISAYAERLLQGLNDIDWSESIKESQRNWIGKSVGALVTFNVKNHDEVIEVFTTRPDTIFGVTFMTLAPEHDLVAKITTPEQKEAVEAYIEKTAKRSERERMADVKTISGVFTGAYAEHPFTKEAIPVWIGDYVLAGYGTGAVMAVPCGDERDYAFANFFKGQNGMQEIKNIFANVDISEAAYGSKDNVEIAASDFLNGLNYKDATAKAIYKLEEIGQGKGKTNYRLRDAVFSRQRYWGEPFPVYYVNGLPKMIDTQHLPIILPEVEKYLPTEDGLPPLGNAAVWAWDIKENKVVNTDLVDNVSIFPLELNTMPGWAGSSWYWMRYMDAHNENEFASKEALAYWENVDLYIGGSEHATGHLLYSRFWNKFLKDKGFAPTEEPFKKLINQGMILGTTAYVYRLEGTNTFVSKNKIKGQNVQPIRVDVHFVNSSDELNIEKFKAWREDFNTAEFIFDENGKYIVGREVEKMSKSYYNVVTPDDICAEYGADTLRLYEMFLGPLEQAKPWNTAGISGVFGFLKKLWRLYFDDNGLIVNNDEPTKDNLKSLHKTIKKVAEDIENFSFNTSVSQFMICVNELSSQNCHSRAILEPLAILVSPYAPHIAEELWAQLGHKTSISEVAFPVFDAKHLVETNKEYPVSFNGKMRFTIELPLDLTAAQIEEIVMKDERTQKQLDGRIPNKVIIVPGKIINLVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDUA_SALTY
Sequence: MQQEALGMVETKGLTAAIEAADAMVKSANVMLVGYEKIGSGLVTVIVRGDVGAVKAATDAGAAAARNVGEVKAVHVIPRPHTDVEKILPKGISQ
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Bacterial microcompartment shell protein PduA, Bacterial microcompartment protein homohexamer, BMC-H, Propanediol utilization protein PduA.
What is the protein family that this protein belongs to?
Belongs to the bacterial microcompartments protein family.
What are the subcellular locations of this protein?
Bacterial microcompartment. Note=The C- terminus probably faces the interior of the BMC (Probable). Modeling suggests the concave face (with both termini) is in the interior of the BMC (Probable).
Protein: YR325_MIMIV
Sequence: MSTYIIINIALLIAIVALIFFLSKKTKSEASYVKSDITNKSYLVQNLPNKEEAAHILGIIDKRISILDDYLRENINKFTEYKPYIEQFNNRIKKLTLYENAPDGKYTSFTVDKGKEIALCLRSRKTGQIHDINLVMYVTLHELAHVACPETDHTELFKKIFIFLIKISIDLNIYKHIDYEADPAEYCGLVIDEDLLK
What are the official names of this protein?
Uncharacterized protein R325.
Protein: RK36_EUGLO
Sequence: MKVYSSVRKICKSCGLIRRHGKLFVRCINSKHNQRQN
What are the official names of this protein?
50S ribosomal protein L36, plastid.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid.
Protein: AATC_RAT
Sequence: MAPPSFFAQVPQAPPVLVFKLIADFRDDPDPRKVNLGVGAYRTDDSQPWVLPVVRKVEQKIANDHSLNHEYLPILGLAEFRSCASQLVLGDNSPALRENRVGGVQSLGGTGALRIGADFLGRWYNGTDNKNTPVYVSSPTWENHNGVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIFVLHACAHNPTGTDPTEEEWKQIAAVMKRRFLFPFFDSAYQGFASGDLEKDAWAIRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVGKEHDSVLRVLSQMEKIVRITWSNPPAQGARIVATTLSNPELFKEWKGNVKTMADRILTMRSELRARLEALKTPGTWSHITEQIGMFSFTGLNPKQVEYLVNEKHIYLMPSGRINMCGLTTKNLDYVATSINEAVTKFQ
What is the function of this protein?
Biosynthesis of L-glutamate from L-aspartate or L-cysteine.  Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system.  Acts as a scavenger of glutamate in brain neuroprotection.  The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis.  Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide.  Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST).  Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
What are the official names of this protein?
Aspartate aminotransferase, cytoplasmic, cAspAT, Cysteine aminotransferase, cytoplasmic, Cysteine transaminase, cytoplasmic, cCAT, Glutamate oxaloacetate transaminase 1, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_VEREI
Sequence: MADPLDHCPDPAQMDPAQADARIRALREQLVHWAHQYHVLDAPSVPDAEYDRAFQALQALEAAHPALITPDSPTRRVQGAVLQGLTPVRHALPMLSIQTETDTGAGGAQAFDARVRRELGLTDADPAIEYVVEPKFDGLAMGLRYENRRLVQAATRGDGEIGEDVTHNIRTIRQIPLGLPDDAPALLEVRGEVYMRRADFDALNQRQRAQSGKTFVNPRNAAAGAVRQLDANITAQRPLRFFAYGLGAVTAPGEGGPAWRTHYALLQTLKSWGFPVAEQVGIAHGASQLAALHEQIGARRDALPYDIDGVVYKVNALQLQRDLGFKTREPRWAVAHKYPAQEMPTRVEGIELQVGRTGKLTPVARLAPVFVGGVTVTNATLHNLFEIRKKQVRVGDTVTVRRAGDVIPEVVGVLPGQRSAYVANFRMPAHCPVCGSAVVREKGEANHRCTGGLFCAAQRKEALLHFAARRALDIEGLGDKLVDQLVDAELVRGLPDLYRLDLVALSALDRMAEKSAQNLLDALEKSRQTTLPRFLFGLGLRHVGEATAKDLARHFGTLDAIMNASVEQLLQVSDIGPVVAQSLHCFFQQPHNREVVAQLRACGLRWPEGAPPERPAQRLAGKSVVLTGTLPTLGRDAARDLLEAAGAKVTGSVSKKTSYLIAGAEAGSKLAKARELGIPVLDEAGMLALLAGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RNC_PARUW
Sequence: MLPRILYMNPIEHVIRQAPAIEAKLGYTFKDPQLLVLAFVHRSFINENREVNQHNERLEFLGDSVLGMLISDYLYCKLPKTPEGQLSYLRSRLVEASSCVHYIQSLDLSGYLLLGKGERMNDGRGRESILADLFEAIIGAIYLDGGLQAAKDFLFKNFHQHIEIILATPLRNWKALLQDYCQKNYQQTPLYQVLHESGPDHSKVFQISVWIQDRELGRGKGTSKKEAQQAAAADALSRVELP
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2A2_CERCE
Sequence: MRTLWIVAVWLMGVEGNLFQFGKMIKHKTGKSALLSYSGNPCYCGWGGQGPPQDATDHCCFVHDCCYGEENACYPKTAFTLKFENQIIICDEDPCNYAVCMCDRVAAICGGENVATSDAKYLFYRSMGCEEESVQC
What is the function of this protein?
Snake venom phospholipase A2 that inhibits blood coagulation and platelet aggregation induced by ADP and arachidonic acid.  Inhibits tumor cell adhesion and migration in a dose-dependent manner.  Abolishes the attachment of human brain microvascular endothelial cells (HBMEC) to fibrinogen (IC(50)=0. 2 uM) and dramatically reduces its adhesion to fibronectin (IC(50)=0. 3 uM), whereas no effect is observed on type I collagen, vitronectin or laminin 1.  Also blocks the cell migration toward fibronectin and fibrinogen.  These effects are not dependent of the catalytic activity, but are mediated by alpha-5/beta-1 (ITGA5/ITGB1) and alpha-v-containing (ITGAV) integrins.  Also shows anti-angiogenic activity in chicken chorioallantoix membrane assay.  Has a relatively high enzymatic activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 CC-PLA2-2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_PYRAR
Sequence: MTGLPDQLRRPVRGMRDWMPQQLYALRRMEEVLSSVAEQYGYRRVETPVVEHFEVLAKKAGQEVINEIYYFRDKAGRELGLRFDMTVPIARVLSYNLDLPRPVRWYYFSKVFRYDEPQHGRYREFFQFGVELIGSASPRADAEVVQLLAASLEAAGASKYVIRINDRRAVDKLLESLGALSHRDAVYRALDKKLKLPREEVIGIMTSGGLPRDAAEKIYDTASEMSLDEAVEVLRRLDGRLGEAYAKFVKYLEAAVPLERFKFDMSIVRGLDYYTGVVFEAFVGDYWLAVGGGGRYDDLLELYSGVKIPALGFAIGVERLMEAVGLQSVEKPLDYYIYIFDDDAYKHAVALANRLRKQGHSVVVELGEKNLKDVFEYVLKIGTRYLVLIGRKELEKGVVKIRDLQKRGEVEVPLSALLS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHER_CHAGB
Sequence: MASAEETFFSAARSRRLACDRCHRHKLRCERSSVIVNGGVAVPLGPCKRCLKACIPCQTVQTISGAFTAAKTGDTPVPRRSAREADQAASPAKRAPSPARRPTASTPRNVPGLIHDDTLSGTDTAPFEISVADAAMLDVSNFDFSGSEFIDLGSNGVLSSPTPIQSPPDHGSLIRDSEIRDRTPIPPHNQPPPRYDDFANDLSCFGTMAPKDDTISTLPALTDVEKASTGSSKSAPERGPREECSQRLLEIHGLLLNELQCITPADVTDALMFPENGSFSGRTRTGQGPGNTVVHRVLFTSERLIELLSIIRAADTAINGDKREAGIGPRNTSSFVDLPIVISILTCYVGLLSVYHAIFSHIYEALRVYEPLRAAKIRQRAWTRRGSVPGPKPGPGLVQPRAIYGADEAGGRPALNVLGIRIQLEIMTHMLEQIDSALFGPRVAHGADGDEGRTDTINRGGEVMFGHPATKALLATMLSHEGYDSGVPVGPFADGDGDDDDDDGYMEGMRGCRMGFRTLMGLQKNIRRLLRTNSFG
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of chaetoglobosin A which has a unique inhibitory activity against actin polymerization in mammalian cells (PubMed:23611317, PubMed:33622536).  Chaetoglobosin A and its intermediates are involved in the morphological differentiation of C. globosum (PubMed:33622536).  Binds directly to asymmetric direct repeats present in the promoters of the chaetoglobosin A cluster genes (PubMed:33622536).
What are the official names of this protein?
Transcription factor cheR, Chaetoglobosin A biosynthesis cluster protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL28_CHLCV
Sequence: MSRKCPLTGKRPRRGNSYTIRGIAKKKKGIGLKVTGKTPRRFFPNMITKRLWSTEENKFLKLKISTSALRLIDKLGLEKVIARAKSKGL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PRIS_NITMS
Sequence: MNETDIKFLESAFKKYYFEQFELIRVPERTSEREFGYQKFNSGMTRHISVKDDKELHLLLMQNVPSDVYCSNAYYSFPNLPMNEKDWKEADLIFDIDAKDLNLSCRGNHTLSICNECHEISNNSEKCSKCNSTKLEKKSLPCKNCIDSSKIEVKKLSEILTNDLSVNKDDIQVYFSGNEGFHIYVYNSQFQQNGSRERSELVDYIMFNGAIPEKFGMKKFKPNRNSFPDFDEAGWKGRFSKYVYGSKSKRSKIVSELLSNGYSSFQKTLDDVSENIGTKIDPNVTMDIHRIFRLPGSINSKSGLTKIHCKDLVKFDAYVDSSFLSDDSVEVLANCPIEFKLKNKKFGPYHNEKVSVPTFAAVYMVCKKLATIA
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.