PharMolix/UniProtQA huggingface dataset:
Protein: RL11_BIFLD
Sequence: MAPKKKVSALIKLQIQAGKANPAPPLGPALGSHGVNIMDFCKAYNAQTQDKMGQVIPVEITVYEDRSFTFVLKTPPAAALLKKAAGVEKGTENPLTHKVGSVTKAQVREIAEIKMEDLSARDIEAGMKIIEGTARSMGITVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NDK_STAAW
Sequence: MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMELAETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIRGDLGLTVGRNIIHGSDSLDSAEREINLWFNENEITSYASPRDAWLYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PILQ_NEIGO
Sequence: MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVLEYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQAATPAKQTNIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTALQRSLDVADFKTPVQKVTLKRLNNDTQLIITTTGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVSGKMTLSLKDVPWDQALDLVMQARNLDMRQQGNIVNMAPRRAACQRQSLLTSGKRHCRSGRAVFPKLPIEIQKCGRIPQHPALDNADTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGRKKLKNETSAFGWGVNSGFGGGDKWEAKPKSTCRLPCRKQHFAGARDFSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTTRSGGGNSTNTELKKAVLGLTVTANITPDGQIIMTVKINKDSPRQCASGNNTILCISTKSLNTQAMVENGGTLIVGGIYEENNGNTLTKVPLLATSPLSATSLKHSGKNRPPRTADFQLPPREL
What is the function of this protein?
Required for type IV pilus biogenesis and competence.  Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.
What are the official names of this protein?
Type IV pilus biogenesis and competence protein PilQ, Outer membrane protein Omc.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. PilQ subfamily.
What are the subcellular locations of this protein?
Cell outer membrane. Note=Associated with the membrane through its C-terminus.
Protein: NRDI_STRP3
Sequence: MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYLLIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQKLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHTSH
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: XNI_ECOUT
Sequence: MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQRGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: SLB_PROTO
Sequence: DCPSDWSSYDEHCYRVFQQKMNWEDAEKFCTQQHKGXHLX
What is the function of this protein?
Platelet antagonist that specifically and reversibly binds to a site on platelet glycoprotein Ibalpha (GP1BA) close to or identical with the site for vWF binding.  It inhibits the binding of vWF to platelets and vWF-dependent shear-induced platelet aggregation.
What are the official names of this protein?
Snaclec tokaracetin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: MSRB_PSEU2
Sequence: MDKLQKTLEEWKQMLDPEQYNVCRLKGTERPFSGKYDKVKTDGIYHCICCDEPLFDSTTKFDSGCGWPSFYAPLENSAVIEVRDMSHGMIRTEVVCAKCDAHLGHVFPDGPPPTGLRYCINSVCLDLVPRS
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: LCTL_MOUSE
Sequence: MKPVWVIILGWILLVPRVGTAWRGPPEEASFYYGTFPPGFSWGVGSSAYQTEGAWDEDGKGPSIWDAFTHGRKEQVLGGDTADTACDSYYKVQEDIALLKELQVSHYRFSLSWPRLLPTGVRAEQVNKRGIKFYSDFIDALLKSNITPVVTLHHWDLPQMLQVAYGGWQNVSMTRYFSDYADLCFEVFGDRVKHWLTFSDPRTMVEKGYETGLHAPGLRLQGTGLYVAAHHIIKAHAQAWHSYNNTWRSKQHGLVGISLNCDWGEPVDIDNPDDIEAAERYLQFCLGWFANPIYAGDYPQVMKDHIGTKSAEQGLEMSRLPTFSLQEKSYLKGTSDFLGLGHFTTRYITQRKYPSHQGPSYQNDRDLVELVDPNWPEMGSPWLYSVPWGFRRLLNFAQTQYGDPPIYVTESGAPQKLHCTQFCDEWRIQYLKGYINEMLKAIKDGVDIKGYTSWSLLDKFEWEKGYADKYGFYYVEFNVRNKPRYPKASVQYYKEIITASGFPNPQEVESWRLKALETCSINNQMLATEPLLRHMHVASEIVVPTVCALSILTAALMLTLLLRRRG
What is the function of this protein?
Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens.
What are the official names of this protein?
Lactase-like protein, Klotho/lactase-phlorizin hydrolase-related protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: IGF1R_HUMAN
Sequence: MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
What is the function of this protein?
When present in a hybrid receptor with INSR, binds IGF1.  PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin.  In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.
What are the official names of this protein?
Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I receptor.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PSBK_TRIV2
Sequence: MEAALLLAKLPEAYQIFDPLVDVLPIIPVFFLLLAFVWQAAVGFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: GCH41_BURO0
Sequence: MNQMNPAFVMPDVQSTVDTRQIPIQRVGVKAVRHPLTVCTESGDVQPTVGVWNLDVRLPADQKGTHMSRFVALLEENRAPLTVERFRAMLASMLVKLEAEAGRIEVTFPYFVNKTAPVSGVQSLLDYEVTLAGESRNGDTRLFLKVLVPVTSLCPCSKKISQYGAHNQRSHVTIDAELAADLPVEALIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDVAQRLDADERVVAYVLEAENFESIHNHSAYALIERDKRQAA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2 1.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: GALT_LATSS
Sequence: MQARELIQKFITKVSTFPETTYTAEDEQYLFNVVLDLVGEGDETPVVAQETTTLIDLKEALVQLAVDHQRIQDLAAERDILGAKLMDLVTPLPSAVNKRFWTLYEKDPEKALAYFYELSQANDYIKVAAIAKNIAYDVPTKYGDLEITINLSKPEKDPKQIALAKTMKQTGYPKCQLCLENEGYAGRLDFPARRNHRIVRFDLEQQTWGFQYSPYAYFNEHSIFLDGKHEPMVIDQTTFKNLLQIVKQFPGYFAGSNADLPIVGGSILTHEHYQGGRHDFPMAKAPISTPLQFAGYDDIQAGIVEWPMSVMRLTGSDAKRIETLAADILTKWQHYSDPEVQVLAQEADGTPHHTITPIARMRGDQYEIDLVLRDNQTSPEHPDGIYHPHADVQHIKKENIGLIEVMGLAILPPRLKSEMAEVEKYLCDQPNEMAAYHKTWADQIKADHSAITPANVTTLVQNEVGKVFMRVLEDAGVFKRDAKGQAAFIKFTERVNNA
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRTA_ASPNG
Sequence: MKFSTILTGSLFATAALAAPLTEKRRARKEARAAGKRHSNPPYIPGSDKEILKLNGTTNEEYSSNWAGAVLIGDGYTKVTGEFTVPSVSAGSSGSSGYGGGYGYWKNKRQSEEYCASAWVGIDGDTCETAILQTGVDFCYEDGQTSYDAWYEWYPDYAYDFSDITISEGDSIKVTVEATSKSSGSATVENLTTGQSVTHTFSGNVEGDLCETNAEWIVEDFESGDSLVAFADFGSVTFTNAEATSGGSTVGPSDATVMDIEQDGSVLTETSVSGDSVTVTYV
What are the official names of this protein?
Aspergillopepsin-2, Acid protease A, Aspergillopepsin II, Proctase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase G1 family.
Protein: SYGB_STRPF
Sequence: MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDIQTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTDAIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVHTLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQFVIADAKERQEMIVEQIKAIEAAQGVQVDIDADLLNEVLNLVEFPTAFMGSFDAKYLDVPEEVLVTSMKNHQRYFVVRDQEGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQKLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIYKFDLLTGMVGEFDELQGIMGEKYARLAGEDAAVATAIREHYLPDAAGGALPETKVGAVLALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYDLSFDSLTYANKADVMNFIRARVDKMMGKAVPKDIREAVLESSTFVVPEMLAAAEALVKASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQQLEQVFALSPVINDFFDNTMVMAEDQALKNNRLAILSDLVSKAKAIAAFNQLNTK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_CERSK
Sequence: MANSPQSKKRARQAEARAAVNKARRSRIRTFLRKVEEAIATGDASVAAAALKTAQPELARGVTKGVLHKNTVARKMSRLAHRVKVLSQPAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: APOF_HUMAN
Sequence: MTGLCGYSAPDMRGLRLIMIPVELLLCYLLLHPVDATSYGKQTNVLMHFPLSLESQTPSSDPLSCQFLHPKSLPGFSHMAPLPKFLVSLALRNALEEAGCQADVWALQLQLYRQGGVNATQVLIQHLRGLQKGRSTERNVSVEALASALQLLAREQQSTGRVGRSLPTEDCENEKEQAVHNVVQLLPGVGTFYNLGTALYYATQNCLGKARERGRDGAIDLGYDLLMTMAGMSGGPMGLAISAALKPALRSGVQQLIQYYQDQKDANISQPETTKEGLRAISDVSDLEETTTLASFISEVVSSAPYWGWAIIKSYDLDPGAGSLEI
What is the function of this protein?
Minor apolipoprotein that associates with LDL.  Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport.  Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
What are the official names of this protein?
Apolipoprotein F, Apo-F, Lipid transfer inhibitor protein, LTIP.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein F family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNFD_SHEPA
Sequence: MAFKLASSPHLKVQLQTQSVMRRVILCALPGIAAQCYFFGFGVLIQVMLAIVVALTAEAAVLALRKRAVLSTISDNSALLTAILIGVAIPPIAPWWLVVIGTLFAIVLVKQLYGGLGQNIFNPAMAAYVMLLISFPVQMTSWSIPTAIAQNPMDIGLTLQAIFGSMSAEQLSLYKLGFDGVAMATPLDTVKTDLSLGLTTSESLTKAIFSDGYGVGWFWVNMAYLAGGLIMLKLKVIRWHISFAILGSLFVCSSFGYLLSPDTHVGPLLQLFSGATMIAAFFIATDPVTAATSVKGRLLFGTLIGVMVYVIRTYGGYPDAFAFAVLLANLCAPFIDYYVKPRTYGHRTGN
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS2_PSEPK
Sequence: MSQVNMRDMLKAGVHFGHQTRYWNPKMGKYIFGARNKIHIVNLEKTLPMFNDALSFVERLAQGKNKILFVGTKRSAGKIVAEQAARCGSPYVDHRWLGGMLTNYKTIRASIKRLRDLETQAEDGTFAKLTKKEALMRSRDLEKLDRSLGGIKDMGGLPDALFVIDVDHERIAITEANKLGIPVIGVVDTNSSPEGVDYIIPGNDDAIRAIELYMTSMADAVIRGRNNVAGGTEVYAEEAAAPAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: DPO3A_STRP1
Sequence: MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEIEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYFCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTAFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDALTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDITAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSVTEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK2_MANES
Sequence: MAIHLYKTSTPSTRNGAVDSQAKSNTRNTRKNLIYGQHRCGKGRNARGIITARHRGGGHKRLYRKIDFRRNEKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIISGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNTGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPATPWGYPALGRRSRKRNKYSDNLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RAD60_SCHPO
Sequence: MDNLDEDDLAFFSKPIKKPPLNYAKQLIASSSDSEEESELDTNKQALEHINAQKNITHNENKSAEPLSRQSTILDADEGNQDVSDTTPNACLNEGRHSPKSAISCVTQPVSPVYNTRAAANLRNNSINSEAALSTTSSLLDDDFARRLEEIDRQVQEFEKSSSDMDVQIHTHKREIEEDDDNTSADVPLLKHSKSDHSTLYHSKSEFSTNEPVISVVLQLAVIGQRIPNSNISLPRDWEAPLFFKVKSNQQFRRVRIAYSERKKVDNVVLVFQNQRLWDYGTPKGAGMLKVDTRLVVHAYCHSDFISLKRIKELEVEKLSSVTEDSTAQTCKLITLLLRSSKSEDLRLSIPVDFTVKDLIKRYCTEVKISFHERIRLEFEGEWLDPNDQVQSTELEDEDQVSVVLD
What is the function of this protein?
Required for repair of DNA double strand breaks which occur during replication, or induced by UV or gamma radiation, via recombination between sister chromatids.  This has a subsequent role in the maintenance of chromosome structure.  May work in conjunction with the Smc5-Smc6 complex.
What are the official names of this protein?
DNA repair protein rad60.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYC_PHOV8
Sequence: MENKLTIYNTLSRQKELFVPLHAPHVGMYVCGPTVYGDAHLGHARPAITFDILFRYLTHLGYKVRYVRNITDVGHLEHDADEGEDKIAKKARLEQLEPMEVVQYYLNRYHKAMEALNVLPPSIEPHASGHIIEQIELVEEILKNGYAYESEGSVYFDVAKYNKDHHYGKLSGRNLDDVLNTTRELDGQSEKRNPADFALWKCAQPEHIMRWPSPWSNGFPGWHCECTAMGKKYLGEHFDIHGGGMDLIFPHHECEIAQSVASQGDDMVHYWMHNNMITINGQKMGKSYGNFINLDEFFHGTHKLLTQAYSPMTIRFFILQAHYRSTVDFSNEALQAAEKGLERLTEAVKGLERITPATQTTGIEGVKDLREKCYTAMNDDLNSPIVIAHLFDGARMINTVLDKKATISAEDLEELKSMFHLFMYEILGLKEEAANNEAHEEAYGKVVDMLLEQRMKAKANKDWATSDKIRDELAALGFEVKDTKDGFTWKLNK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRX1_MONPV
Sequence: MAEEFVQQRLANNKVTIFVKFTCPFCRNALDILNKFSFKRGAYEIVDIKEFKPENELRDYFEQITGGRTVPRIFFGKTSIGGYSDLLEIDNMDALGDILLSIGVLRTC
What is the function of this protein?
Displays thioltransferase and dehydroascorbate reductase activities.
What are the official names of this protein?
Glutaredoxin-1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
Protein: DID4_YEAST
Sequence: MSLFEWVFGKNVTPQERLKKNQRALERTQRELEREKRKLELQDKKLVSEIKKSAKNGQVAAAKVQAKDLVRTRNYIQKFDNMKAQLQAISLRIQAVRSSDQMTRSMSEATGLLAGMNRTMNLPQLQRISMEFEKQSDLMGQRQEFMDEAIDNVMGDEVDEDEEADEIVNKVLDEIGVDLNSQLQSTPQNLVSNAPIAETAMGIPEPIGAGSEFHGNPDDDLQARLNTLKKQT
What is the function of this protein?
Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB).  Acts a component of the ESCRT-III complex, which appears to be critical for late steps in MVB sorting, such as membrane invagination and final cargo sorting and recruitment of late-acting components of the sorting machinery.  The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complex assemblies.  Can directly stimulate VPS4 ATPase activity.  The DID4/VPS2-VPS24 subcomplex is required for the VPS4-dependent dissociation of ESCRT-III.
What are the official names of this protein?
DOA4-independent degradation protein 4, ESCRT-III complex subunit VPS2, Vacuolar protein-sorting-associated protein 2, Vacuolar protein-targeting protein 14.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: PROA_CLOBA
Sequence: MNELILKGERAKEASYVLMNATTSEKNDALIKMGQKLLENKDYIIAENEKDLENAMLKGTSKAMLDRLSLDEKRLEDMADGLNQLVNLNDPIGEVITMWKRPNGLQIGKQRVPMGVIGIIYEARPNVTCDAAGLCLKAGNAVILRGGSEAINSNKAIVKALCEGIKESGLPEYSLQLIENTSREIANEMMRLNEYIDVLIPRGGAGLIQAVVKNATVPVIETGVGNCHVYVDEEADFKMAEDIIINAKTSRPAVCNAEEKLLVNEKIAEEFLPKIISALREKNVEVRGDSNVMKIADDVKEATDEDWGKEYLDFIIGIKIVNNIDEAIKHINRYGSGHSEAIITNNYQNSQKFLQRVDAAAVYVNASTRFTDGCEFGFGAEIGISTQKLHARGPMGLNELTTTKYIIYGNGQIR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_BORA1
Sequence: MTSRPALRRYAVIGNPITHSRSPQIHAMFAAQTGISLEYERIPAPLDGFRATAEAFFLAGGQGLNVTVPFKQEAFELAREHLSARARMAGAVNTLTWRDGVLQGCNTDGVGLVNDLIRLGVMLQGARLLLVGAGGAARGVLQPLAEAGCAEIRIVNRSPGRAAELLAAWTASGIPGGVQTSAGALDEAGGAWDIVINATASSLHDLAPALPGGLYAPGALAYDMVYGARPTPFMRQARADGAALTADGLGMLVGQAAESFFIWHGLRPDPTAVLTTLRANLLAED
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: SCP2_BOVIN
Sequence: MSLVASQSPLRNRVFVVGVGMTKFTKPGVENRDYPDLAKEAGQKALADAQIPYSAVEQACIGYVYGDSTSGQRAIYHSLGLTGIPIINVNNNCSTGSTALFMARQLIQGGLADCVLALGFEKMVKGPIAVNIQDKANPIDKHIEVMVNKYGLSPSPVAPQMFGNAGKEHMEKYGTTLEHFAKIGWKNHKHSVNNPYSQFQKEYSLDEVMTSRKIFDFLTVLQCCPTSDGAAAAILASEAFVQKHNLKPKAVEILAQEMVTDMPSSFEGKSIIKMVGFDMSKEAARRCYEKSGLRPSDIDVIELHDCFSANELITYEALGLCPEGQGGKLVERGDNTYGGKWVINPSGGLISKGHPLGATGLAQCVELCWHLRGEAGKRQVPGAKVALQHNIGIGGAVVVTLYKMGFPEAARTHQIEAAPTSSSVDGFKANLVFKEIEKKLEDEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDLLALMTGKMNPQTAFFQGKLKINGNMGLAMKLQNLQLQPGKAKL
What is the function of this protein?
Mediates the transfer of all common phospholipids, cholesterol and gangliosides from the endoplasmic reticulum to the plasma membrane.  May play a role in regulating steroidogenesis (By similarity).  Stimulates the microsomal conversion of 7-dehydrocholesterol to cholesterol (By similarity).  Also binds fatty acids and fatty acyl Coenzyme A (CoA) such as phytanoyl-CoA.  Involved in the regulation phospholipid synthesis in endoplasmic reticulum enhancing the incorporation of exogenous fatty acid into glycerides.  Seems to stimulate the rate-limiting step in phosphatidic acid formation mediated by GPAT3.  Isoforms SCP2 and SCPx cooperate in peroxisomal oxidation of certain naturally occurring tetramethyl-branched fatty acyl-CoAs (By similarity).
What are the official names of this protein?
Sterol carrier protein 2, SCP-2, Acetyl-CoA C-myristoyltransferase, Non-specific lipid-transfer protein, NSL-TP, Propanoyl-CoA C-acyltransferase, SCP-2/3-oxoacyl-CoA thiolase, SCP-2/thiolase, SCP-chi, SCPX, Sterol carrier protein X, SCP-X.
What are the subcellular locations of this protein?
[Isoform SCP2]: Peroxisome. Cytoplasm. Mitochondrion. Endoplasmic reticulum. Mitochondrion. SUBCELLULAR LOCATION: [Isoform SCPx]: Peroxisome.