PharMolix/UniProtQA huggingface dataset:
Protein: IXTPA_CHLPN
Sequence: MKIVIASSHGYKIRETKTFLKRLGDFDIFSLSDFPDYKLPQEQEDSITANALTKGIHAANHLGCWVIADDTMLRVPALNGLPGPLSANFAGVGAYDKDHRKKLLDLMSSLESLVDRSAYFECCVVLVSPNQEIFKTYGICEGYISHQEKGSSGFGYDPIFVKYDYKQTFAELSEDVKNQVSHRAKALQKLAPHLQSLFEKHLLTRD
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: GSA_MYCPA
Sequence: MGSSDQATAHARAQAASARLFDDACAVIPGGVNSPVRAFTAVGGTPPFITAARGCRLTDADGNHYVDLVCSWGPMILGHAHPAVVEAVAKAAASGLSFGAPTPAESELAAEMIARVAPVERIRLVNSGTEATMSAVRLARGFTGRAKIVKFSGCYHGHVDALLADAGSGVATLGLPSSPGVTGATAADTIVLPYNDIDAVRQAFTEFGDQIAAVITEASPGNMGVVPPAPGFNAALRALTADHGALLIVDEVMTGFRVSRSGWYGIDPVDADLFTFGKVMSGGLPAAAFGGRAEVMERLAPLGPVYQAGTLSGNPVAMAAGLATLRHADAAAYAALDANADRLARLLSDALTNAGVPHQIPRAGNMLSVFFTDTPVTDFASARATQTWRYPPFFHALLDAGVYPPCSAFETWFVSTALDDDAFDRIAAALPAAARAAAGADEGNS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_IPMAE
Sequence: MVQKMLTSRGLFLILTMLNLSQVPSIMGEQRWAILSTFPKPMPVRHDAIVFPKFFTTNKTVDLPYLLYDPTAPLGENRSLLEQGSLCFQINGPGNCINLTARALGKFNEHRGWVSTTQDTSNVEITFTNRTFWQEVNWVNGTFLPPNFSDKEHLHQPKIAPHCSLEDEGLILPWSDCQSSIIRWVDQSKTFSFSPNMIDDPEKEFVMKKGLFIQDFRMHPFHKWVLCGVNGSCTELNPLIFIQGGAVGKASFTGISRFAQYWGIHDASQDSYGYTNTSVEITGFNKTLVNQINYPSTPVCVYPPFLFILSNDSFEVCSNDSCWISQCWDVTKNTRAMVARIPRWIPVPVETPSTLSMFRQKRDFGITAAMIIAISASAAAATAAGYAMVSAVSGTKLNQLSADLADAITVQTSASTKLKGGLMILNQCLDLAEEQIGVLHQMAQLGCERKLEALCITSVQYENFTYAANLSRQLSLYLAGNWSERFDETLEALIAAVLKINSTRMDLSLTEGLSSWISSAFSYFKEWVGVGLFGVATCCGLVVMLWLVCKLRTQQTRDKVVITQALAAIEQGASPEIWLSMLKN
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: YO248_YEAST
Sequence: MTPLLCLHHLLQQVSVTKIQTTKMQRSSPLNRLQLPMVASQSQSLSLSPMSPLPSTLQSPQIRLHNTLLSPVHLLLPLPLQVTYNGTTPLRLLIRPVGEL
What are the official names of this protein?
Putative uncharacterized protein YOR248W.
Protein: UVRC_DESAL
Sequence: MSEIEKKLATLSNGPGVYLMKDESGEIIYVGKARSLKKRVSSYFLEKPNRDLKTGILVKKIASFDAILVTTEKEALILEANLIRKHKPRYNILLKDGKRFPSLRIDVRTSYPRLEVVRKVKKDGAIYFGPFSSAGKLRSTLKIINKTFQLRKCKQKEPPKRNRPCLNYQMGQCLGPCCLPVDRDEYLDMVNEVILFLKGRTNDLLQKIKEQMAAASERQEYELAARLRDRMFAIQATVEKQAAVTTDFVDRDVIGIDREPEGSAISVLYIRGGFLLGSRNYNFDEVLGTDSESIQAFLRQYYDKDRFIPDEVFVPCQLENMELMEQWLTETAEKRVVLHWPQRGEKTRLIEMANENAHEALKDRISSENVFKSLLERLQKRLRMDRPPRRIECFDISHTGGNQTVASMIVFEDGKEAKSEYRTFNIDSLDHPDDYAAMHEVMARRFSPDKDWPTPDVLLIDGGKGQLSITASVLDGLGVMGAFEVISIAKKDEAKKETMDKIYRPGQANPVVFGRDGDVLLFLQRVRDEAHRFAITTHRKKRAKTIRKSALDSVPGIGEKRKKALLRHFGSIKRLKEASPEDIAQVPGISVKRAQEILEALDA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_CHLTA
Sequence: MSVPDRKRALEAAIAYIEKQFGAGSIMSLGKHSSAHEISTIKTGALSLDLALGIGGVPKGRIVEIFGPESSGKTTLATHIVANAQKMGGVAAYIDAEHALDPNYAALIGANINDLMISQPDCGEDALSIAELLARSGAVDVIVIDSVAALVPKSELEGEIGDVHVGLQARMMSQALRKLTATLARTNTCAIFINQIREKIGVSFGNPETTTGGRALKFYSSIRIDIRRIGSIKGGENFDIGNRIKVKVAKNKLAPPFRTAEFDILFNEGISSAGCIIDLAVEKNIIDKKGSWFNYQDRKLGQGREAVREELKRNKELFHELERCIYESVQASQVPAAACVDAESRQVAEAAK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y109_EMEND
Sequence: MSNRIYWHRCSGLNPFQIITSLRLTQPGQRLGIANQGYRRFLLVSSSIADTRELSMSYHPSTYLTQSGNILPSVDKGLCFEKLLETVFLSVGGCVRL
What are the official names of this protein?
Putative uncharacterized 10.9 kDa protein in spoC1 gene cluster region.
Protein: PUR9_SALHS
Sequence: MQQRRPVRRALLSVSDKAGIIEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKIHGGILGRRGQDDAIMEQHHIAPIDMVVVNLYPFAETVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDANEGSLTLDTRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATAQQVQGKALSYNNIADTDAALECVKEFNEPACVIVKHANPCGVAVSTTILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSATEEALKITAAKQNVRVLTCGQWAQRVPGLDFKRVNGGLLVQDRDLGMVSEAELRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYAKENMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSAMASDAFFPFRDGIDAAAAVGVSCVIQPGGSIRDDEVIAAADEHGIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: VES_ESCF3
Sequence: MEYFDIRKMPVNLWRNGAGETREICCFPPATRDFHWRASIASIATNGEFARFPGMERVVTLLEGGEIHLESTDSFSHTLKQLQPFAFSGEQIVKAQLNEGQMSMDFNIMTRCNSCKAKVRIADRTFTTFGSRGGVVFVISGIWQLGDKVLTTDQGACWYDGKHTLRLLQSTGKLLFSEINWLPGYSPDQVQ
What are the official names of this protein?
Protein Ves.
What is the protein family that this protein belongs to?
Belongs to the Ves family.
Protein: THIO_CHLPN
Sequence: MVKIISSENFDSFIASGLVLVDFFAEWCGPCRMLTPILENLAAELPHVTIGKINIDENSKPAETYEVSSIPTLILFKDGNEVARVVGLKDKEFLTNLINKHA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: RS18_LACP7
Sequence: MKRRMTRRRKKVCAFCADKNHKEIDYKDVNKLKRYVSERGKILPRRITGNCAKHQRALTVAVKRARHIALMPYTLD
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SULA_SALSV
Sequence: MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: EZRA_ENTFA
Sequence: MKNNWIIILVLVIVIIAAVLYLIGYFMRKKNQEQLDELEVRKEALFDLPVFEEIDDIKKMHLVGQSQNSFREWNQRWVELSTRSFAELESQIYEVENQNEIFRFMKAKKAVVEANETMTEMEAEVEVIRNGLKELRESEERNSLEVQKALDVYEELSKSLKDDKASFGPAYSEIQKQLRNVEIEFTQFVTLNTSGDPIEAREVLEDAERHTYELEDLMKRIPPMYEELNETFPDQLKEIEEGYNQLLADDYVFPEQNFAEEIQHAKKRVENSMADLEKTEIAAVEVANRDTATAIDALYEVMEREIEAKKYVVTNQKIIDDYISHSLKNNRQLMIELDHVSQSYTLNNNELGRSRGFQTEIEEIIRRQKDLEPRMKEHTVPYSEIQAFYKECYKILDDIENQQLEIDASLKELRKGEKVAQEKVDEYEFRLRSIKRYVEKQRLPGLSADYLEFFYVATDRIEDLSRALNKMRINMDEINRLCDLCEDDLELLDKKTKDLVNAAALTEQMMQYANRYRHTHENIRAALDKSMYLFSTEFRYQDALDEIGTALEAVEPGAFKRIEDFYFKNINNPNLTAI
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: CYB_CEPHA
Sequence: MINIRKTHPLMKILNDAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTSTAFSSVAHICRDVNYGWFIRYLHANGASMFFICLYAHIGRGLYYGSYMFQETWNIGVLLLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAAVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGALFLILALLALTLFAPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILIFIPMLQTSKQRSMMFRPFSQLLFWTLIADLLTLTWIGGQPVEHPYIIVGQLASILYFFLILVLMPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SNA17_LYCMC
Sequence: MKILFVIVLAAFFIGVHCKHGYPVQYSGREKGCKIACVINNASCDGECKRRGGRAGYCYFWKLACFCEYLPNNSPTWDYKTGKCRV
What is the function of this protein?
Binds voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin LmNaTx17.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: URE1_ALIB4
Sequence: MKISKEKYASMYGPTTGDRFRLADTTLIAKIEKDYTIYGEESKFGGGKTVRDGMAQSPTAVDVADLIITNAIIIDYTGIYKADIGIKDGKILAIGKSGNPNLCDGITEGLEIGANTEILSAEGKIITAGGIDTHIHFISPGQINEALSSGVTTMIGGGTGPNTGTNATTCTPGEWNISKMIQSVDDLPLNFGFMGKGNSSSYEALKVQIEAGAMGLKLHEDWGSTPNAIDTCLSVADDFDVQVAIHTDTLNESGFVEATVGAFKNRTIHTFHSEGAGGGHAPDIMKVAGLSNVLPSSTNPTLPYTKNTIEEHLDMLMVCHHLSPKIPEDVSFAESRIRGKTIAAEDVLHDLGAISITSSDSQAMGRVGEVIIRTWQVAHSMKQQRGTLEGDDEKSDNNRIKRYIAKYTINPAIACGIDEYVGSVEVGKMADLVLWNRAFFGVKPEIIIKGGFIALAMMGDSNASIPTPEPNMYRLMFGSLGRASGATSVIFTSKVASSNLKDKLGISKNVLPVKNTRNIGKANMKLNDFIGDIEIDSETYDVKINGEPIESNYVEKVPMARRYFMF
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_CHLP8
Sequence: MDQLIQLVEATQERNDIPEVRPGDTVRIQLKVIEGEKERLQAFEGVVIGDKGAGTSKTITVRKISHGVGVERIIPVNSPNVESITVVRNGKARRAKLFYLRKRTGKAALKVKERKTASAQA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: CRN15_PHYIN
Sequence: MVKLVCAIVGVAGSAFPVDIDASQLVGDLKKAIKAENAMTFTGDAKDLQLFLAKQPVDDESGKEVVPVYRPSAEEMKEESFKWLPDEHRAALKLVEGESDDYIHALTAGEPILGSKTLTTWFYTKNNMELPSSEQIHVLVVVPEQGSSVPTVSQDGVFDHCINPFFLQFRTVDKVGDWLEFSSLLPLTRRQKLYIRSSYQVIANHALFNPNVGMVKYAVVTGTPGVGKSVFVYYVLWRLIKEKKRVLLFDNNGLFYFDGSTMLICLALPSKFNEQFWSPDLWCLVDSMDPTSIPGLPYRLCSVLLASTPRRDCIGEFKKQPPTADVFYMPLWSKEELATIAPMYPHAAAVWENRFDCLGGVPRLVLQDIETDPQALLMSACSSCSLDDCIMLVSIYSEINSKTKIVQTLIHIHSQEPYRKYKVVYASDLAMQLIVRTKWRFDRAKLQSLLGSSDGNPLAQSLCGYIFEFYSMDRLEQGGTFVYRELFSGKRKRTPADGTIDIPRSSQPRQVAERVEVGQHAKQLYVPGTSNYTAIDAWMPQFGGFQMTVGKTHDIKGGAADDLAKLGQNGNRLFFLLPPLYYKTFTKKTPQTIKQYAILVPYPEVRNELSASTLQ
What is the function of this protein?
Secreted effector that elicits necrosis in host plants, a characteristic of plant innate immunity.
What are the official names of this protein?
Crinkler effector protein 15.
What is the protein family that this protein belongs to?
Belongs to the Crinkler effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: AROB_PSE14
Sequence: MQTLKVELGERSYPIHIGEGLLDQPELLTPHIVGRQVAIVSNTTVAPLYLERLTQTLAGYNVLPIVLPDGEAFKNWETLQTIFDGLLTARHDRRTTVIALGGGVIGDMAGFAAACYQRGVNFIQIPTTLLSQVDSSVGGKTGINHPLGKNMVGAFYQPSVVLIDTTSLNTLPERELSAGLAEVIKYGLICDEPFLTWLEEHVDALRGLDQAALTVAIERSCAAKALVVGADERESGVRATLNLGHTFGHAIETHMGYGVWLHGEAVAAGTVMALEMSSRLGWISTQDRDRGIRLFQRAGLPVVPPQDMTEDNFLEHMAIDKKVIDGRLRLVLLRQMGEAVITDDYPKEVLQATLVADYRALVDQLRG
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_NOSP7
Sequence: MGRAKKVVLAYSGGVDTSVCIPYLKQEWGVEEVITLAADLGQGDELEPIREKALKSGASESLVADVKDSFVKDYAFGAIQANALYENRYPLGTALARPLIAKILVETAEKYGADAIAHGCTGKGNDQVRFDVSVTALNPNLKILAPAREWGMSREETIAYGEKFGIPSPVKKSSPYSIDKNLLGRSIEAGLLEDPSFEPPEEIYEMTKAIADTPNEPEYIKIGFHGGIPTTLNGIAKQPVELIEELNQLVGNHGVGRIDMIENRLVGIKSREIYESPAMLVLIQAHRDLESLTLTADVTHYKRGIEETYSQIVYNGLWYSPLKVALDAFIQKTQERVSGTVRVKLFKGNSTIVGRSSDSSLYTPDLATYGADDQFDHKAAEGFIYVWGLPTRIWSRQIKS
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHU1_YEAST
Sequence: MQFEERLQQLVESDWSLDQSSPNVLVIVLGDTARKYVELGGLKEHVTTNTVAGHVASRERVSVVFLGRVKYLYMYLTRMQAQANGPQYSNVLVYGLWDLTATQDGPQQLRLLSLVLRQCLSLPSKVEFYPEPPSSSVPARLLRFWDHIIR
What is the function of this protein?
Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase.
What are the official names of this protein?
Suppressor of HU sensitivity involved in recombination protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: TTLL6_MOUSE
Sequence: MLQCLTSESEEGAEEREESSTEDLEELKEFVTLAFVRENTQKRLQNAQQHGKKKRKKKRLVINLSNCRYDSVRRAAQQYGLREAGDNDDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKLFPKDFHFFPRTWCLPADWGDLQTYSRTRKNKTYICKPDSGCQGRGIFITRSVKEIKPGEDMICQLYISKPFIIDGFKFDLRVYVLVTSCDPLRVFVYNEGLARFATTSYSHPNLDNLDEICMHLTNYSINKHSSNFVQDAFSGSKRKLSTFNSYMKTHGYDVEQIWRGIEDVIIKTLISAHPVIKHNYHTCFPSHTLNSACFEILGFDILLDRKLKPWLLEVNHSPSFSTDSKLDKEVKDSLLYDALVLINLGNCDKKKVLEEERQRGRFLQQCPNREIRLEEVKGFQAMRLQKTEEYEKKNCGGFRLIYPGLNLEKYDKFFQDNSSLFQNTVASRARELYARQLIQELRQKQEKKVFLKKARKEETQGESAGEQARDKVVRLQRQRQQPKCKTVATCPPKQSLHPVTLVSCTSGLLLNIRGLKKGEISESLEQKDTKEAMLIPCKPVSARNYSSVPDLRSANPSCFEPEFHVPNAKVKEVKSAFMVNIESTAQPITSVESSRDATAPISTSLESLASMSLSTSPECSSPESVHMVSYNHKQQKASFHKPMQEKKSKPLMFSKSRHLDLNCTSMKNDINRQYLMSEILQKVQMKKKRPLFPAPKSQYPTLSKERCPHSRSSSRKKEMNSPSVFVLQASHSRAESLNDLLVVATQARLDPRPSRSHSGTTTRDSSTQDPKHTATA
What is the function of this protein?
Polyglutamylase which modifies both tubulin and non-tubulin proteins, generating alpha-linked polyglutamate side chains on the gamma-carboxyl group of specific glutamate residues of target proteins (PubMed:17499049, PubMed:21074048, PubMed:20530212, PubMed:26829768, PubMed:32747782).  Preferentially mediates ATP-dependent long polyglutamate chain elongation over the initiation step of the polyglutamylation reaction (PubMed:17499049, PubMed:21074048, PubMed:20530212, PubMed:26829768, PubMed:32747782).  Preferentially modifies the alpha-tubulin tail over a beta-tail (PubMed:17499049, PubMed:20530212, PubMed:21074048, PubMed:32747782).  Promotes tubulin polyglutamylation which stimulates spastin/SPAST-mediated microtubule severing, thereby regulating microtubule functions (PubMed:20530212).  Mediates microtubule polyglutamylation in primary cilia axoneme which is important for ciliary structural formation and motility (PubMed:22246503).  Mediates microtubule polyglutamylation in motile cilia, necessary for the regulation of ciliary coordinated beating (PubMed:23897886).  Polyglutamylates non-tubulin protein nucleotidyltransferase CGAS, leading to CGAS DNA-binding inhibition, thereby preventing antiviral defense response (PubMed:26829768).
What are the official names of this protein?
Tubulin polyglutamylase TTLL6, Protein polyglutamylase TTLL6, Tubulin--tyrosine ligase-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=CEP41 is required for its transport between the basal body and the cilium axoneme.
Protein: RS10_RHOPS
Sequence: MNGQNIRIRLKAFDHRILDTSTREIVNTAKRTGAQVRGPIPLPTRIEKFTVNRSPHVDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: COFH_METPE
Sequence: MRTMNHDLQGLLSDLKGGHRLGEDEALMLFETRGRDIWTIAAAADERREAVAGDPVTYVRNQNINVTNLCVNACGFCGFSKKPGDDGIYYHSREEIQQKAALAKSRGVSEICTVSGLHPHFTAESYIEIYRWITEAAPGIHLHASNPMEVAYGAERSGMTTREVLTGMKAAGLSSMCGTAAEILVDPVRDTICRGKIPTDEWVRIIREAHSLGIPTTATIMYGHCETEADRVRHLAILRAIQDETHGFTEFVPLSFIHMNTPIYRQGLARAGATGREDLLMVAVARLFLDNFRNIQVSWVKEGIKMAQLGLIAGANDLGGTMYEESISKGAGATNTDYLDPAEMQRVAEDLGRMLERRTTLYDMC
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: ISPG_HALH5
Sequence: MTEITHRTKTRPVKVGNLTIGGNNEVVVQSMTTTKTHDVEATVAEIKRLEEAGCQVVRVACPDMRAAEAIPAIKKQISIPLVVDIHFDYKLALKAIEGGADKIRINPGNIGKRHKVEAVVKAAKEKGIPIRIGVNAGSLEKRILDKYGYPTADGMVESALHHIKILEDLDFHDIIVSMKASDVNLAIEAYEKAAKAFDYPLHLGITESGTLFAGTVKSAAGLGAILNMGIGNTVRVSLSADPVEEVKVARELLKSFGLASNAATLISCPTCGRIEIDLISIANEMEEYISKIRAPIKVAVLGCAVNGPGEAREADIGIAGARGEGLLFRKGEIVRKVPEETMVEELKKEIDKIAEEYFAKQKELEKA
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: Y095_OSHVF
Sequence: MSHEKSVTEFTRDLVGVYINAGVVKSYAKDTKGNTRLYELSNKEIMDIGIEIHSICETDEKEYIDIDYCTEADLKIIRLANTISLLNQLHVAGRVCELPIKTLVHGTSLRGIIDRIIWNKDKKEIEVIDIKSHYIPFILDDPELKGMPQSKRLGYSFQLHVYVEMLDWLFTASPDALRDSFIGSIYNKDEPIHPIICSKLEIPKTITANNLFDILLKERSVFTDVKYTVLIMHIDQNYFKSEYKTGKASVVYESIKCNREWFKKMVFFDLAELERKKSLAEIHKKAAMAKKREEKKKIKQELKKSAKGKK
What are the official names of this protein?
Uncharacterized protein ORF95.
Protein: PSBK_SOLBU
Sequence: MLNTFSLIGICLNSTLYSSSFFFGKLPEAYAFLNPIVDIMPVIPLFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ZSC12_MACNE
Sequence: MASTWAIQAHMDQDERLEVKIEEKKYTTRQDWDLHKNNTHSREVFRQYFRQFCYQETSGPREALSRLRELCHQWLRPETHTKEQILELLVLEQFLTILPEELQAWVQEQHPESGEEVVTVLEDLERELDEPGEQVSAHTGEHEMFLQKMVPLGKEGEPSMPLQSMKAQLKYESPELESQQEQVLDVETGNEYGNLKQEVSEEMKPHGNTSSKFENDMSQSARCGETHEPEEITEEPSACSREDKQPTCDENGVSLTENSDHTEHQRICPGEKSYGCDDCGKTFSQHSHLTEHQRIHTGDRPYKCEECGKAFRGRTVLIRHKIIHTGEKPYKCNECGKAFGRWSALNQHQRLHTGEKHYHCNDCGKAFSQKAGLFHHIKIHTRDKPYQCTQCNKSFSRRSILTQHQGVHTGAKPYECNECGKAFVYNSSLVSHQEIHHKEKCYQCKECGKSFSQSGLIQHQRIHTGEKPYKCEVCEKAFIQRTSLTEHQRIHTGERPYKCDKCGKAFTQRSVLTEHQRIHTGERPYKCDECGNAFRGITSLIQHQRIHTGEKPYQCDECGKAFRQRRKTSYKEILLKNHSEPQAGVNLLLSSLIPEWQSCCRKDL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 12, Zinc finger protein 96.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.