PharMolix/UniProtQA huggingface dataset:
Protein: CUL2_HUMAN
Sequence: MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADHLQFLHAECHNIIRQEKKNDMANMYVLLRAVSTGLPHMIQELQNHIHDEGLRATSNLTQENMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVEDRLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLNNKFNNFIKNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMNFSSKRTKFKITTSMQKDTPQEMEQTRSAVDEDRKMYLQAAIVRIMKARKVLRHNALIQEVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA
What is the function of this protein?
Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins (PubMed:11384984, PubMed:26138980, PubMed:29779948, PubMed:29775578).  CUL2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme (PubMed:9122164, PubMed:10973499, PubMed:11384984, PubMed:12609982, PubMed:24076655).  The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (PubMed:12609982, PubMed:24076655, PubMed:27565346).  The functional specificity of the ECS complex depends on the substrate recognition component (PubMed:9122164, PubMed:10973499, PubMed:26138980, PubMed:29779948, PubMed:29775578).  ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF) (PubMed:9122164, PubMed:10973499).  A number of ECS complexes (containing either KLHDC2, KLHDC3, KLHDC10, APPBP2, FEM1A, FEM1B or FEM1C as substrate-recognition component) are part of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation (PubMed:26138980, PubMed:29779948, PubMed:29775578).  ECS complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (PubMed:27565346).  ECS(LRR1) ubiquitinates MCM7 and promotes CMG replisome disassembly by VCP and chromatin extraction during S-phase (By similarity).
What are the official names of this protein?
Cullin-2, CUL-2.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: Y093_STAAN
Sequence: MIKRVNKLVLGISFLFLIISIFAGCGTGKEAEIKKSFEKTLSMYPIKNLEDLYDKEGYRDDQFDKNDKGTWIVRSSMSIQSNGKDMNIKGMVLYMNRNTRTTNGYYYVDVIEREDKGIHRDNEKRYPVKMVDNKIIPTKEIKDEKIKKEIENFKFFVQYGDFKDLSKYKDGDISYNPEVPSYSAKYQLTNDDYNVKQLRKRYNIPTNKAPKLLLKGTGNLKGSSIGYKKIEFTFVEKKGENIYFSDGLHFNPSEDK
What are the official names of this protein?
Uncharacterized lipoprotein SA0093.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: HIS8_METM5
Sequence: MSIDDKVRAIVKEFKAYVPGKSKEEIARNYGIDPEKIIKLGSNENPWGCSPKIAEKLMNEVSNLHQYPQPINPELMDEISKFTKMPTENIIVGGDGADEVIDNIMRILIDEGDEVIIPIPTFTQYAISAKIHGANIKWAKFDEENGFKLDVESVLNNITEKTKVIFLCTPNNPTGNVIPTEDIKKIVESTDALVMIDHAYIEYSKGEYDLTNWALKYDNVLVLRTFSKVFGLAGQRVGFGVTSKKIVDYMMRIKPIFSLTRASQVSAITALQDKEFFDRCLKEGIESREQIYNGLKKFKQLEVYPTEANYMLVKVKNGMNSSEFCEALLKKGVIVRDCYSFEGLEPYYFRISIGTFEENERFLKIMSEIVE
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: PGPS1_YEAST
Sequence: MTTRLLQLTRPHYRLLSLPLQKPFNIKRQMSAANPSPFGNYLNTITKSLQQNLQTCFHFQAKEIDIIESPSQFYDLLKTKILNSQNRIFIASLYLGKSETELVDCISQALTKNPKLKVSFLLDGLRGTRELPSACSATLLSSLVAKYGSERVDCRLYKTPAYHGWKKVLVPKRFNEGLGLQHMKIYGFDNEVILSGANLSNDYFTNRQDRYYLFKSRNFSNYYFKLHQLISSFSYQIIKPMVDGSINIIWPDSNPTVEPTKNKRLFLREASQLLDGFLKSSKQSLPITAVGQFSTLVYPISQFTPLFPKYNDKSTEKRTILSLLSTITSNAISWTFTAGYFNILPDIKAKLLATPVAEANVITASPFANGFYQSKGVSSNLPGAYLYLSKKFLQDVCRYRQDHAITLREWQRGVVNKPNGWSYHAKGIWLSARDKNDANNWKPFITVIGSSNYTRRAYSLDLESNALIITRDEELRKKMKAELDNLLQYTKPVTLEDFQSDPERHVGTGVKIATSILGKKL
What is the function of this protein?
Essential for the viability of mitochondrial petite mutant.  Catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GPMA_RHIL3
Sequence: MSGTLVLVRHGQSDWNLKNLFTGWKDPDLTELGIQEANTGGAALAEYGIKFDVAYTSVLVRAQHTLKLILDKVGQPDLLTIRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLRDTGARVWPYYLTEILPRVLRGEKVLVAAHGNSLRSLVMVLDKLSREGVLALNLATGVPMVYKLKADSTVASKEVLGDMSGAH
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: SYG_ALKMQ
Sequence: MTTAKSMEKIVALAKSRGFIFPGSEIYGGLANTWDYGPLGVELKNNVKKAWWKKFIQQSPYNVGLDSAILMNPTTWEASGHIGGFSDPLMDCKKCRARFRADKLIEDHFAKDGEDTIVDGWSNEQMASFIDEKAIVCPECDAKEFTDIRQFNLMFKTHQGVNEDTSTEIFLRPETAQGIFVNFKNVQRTARKKIPFGIGQIGKSFRNEITPGNYTFRTREFEQMELEFFCKPGDDLEWFDYWSNFCKKWLLDLSMKETSIRLRAHTEEELSHYSNATTDIEFKFPFGWGELWGIADRTDFDLKQHTEHSGVQLIYQDPVTNEKYVPYCIEPSLGADRVTLAFLVDAYEEEQIDEKDSRIVLKLHPALAPFKAAVLPLTKKLKEQSLELFEKLSDKFMIDYDDAGSIGKRYRRHDEIGTPYCITYDFDTLEDNCVTVRDRDTMEQQRVAIDELEVFLEEKIKF
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_LACDB
Sequence: MDYRNFFTGRPTSEICRDLIGRPFYYQAGGEKIGGYIVESEAYLGIYDRAAHSYGGRRSQANEGLWRAGGTIYIYSQRQYVFFDIACQEEGNPQGVLIRAIEPVWGLDQMLKNRGGKDGVLLTNGPAKLMQAMGIKSRNWDLAPLADSPFVIDLTEKKPAKEIVASPRIGIVQADPAWAQAPLRYYVAGNPYVSGMKKRDWADDHGWL
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: GLGB_PSEA7
Sequence: MSEPMSERERWQLELDKLQRGLQGDPFAFLGPQRDADGEGGVLRAYLPGAQRVELLDEDGATLAELEQSDPGSGLFQHHLERLPARYRLRTHWPDGVQESEDPYAFGPLLGELDLYLFAEGNHRQLASCLGAQLTRHEGVDGVRFAVWAPNAVRVSVVGDFNGWDGRRHPMRRRYPSGVWELFIPRLGAGELYKYELQGHAGLLPLKADPLALACETPPGTASKTCAALRHEWRDQDWLARRAERQGYAAPLSIYEVHAGSWRHRDGRPPRWSELAEELIPYVRQLGFSHIELMPVMEHPFGGSWGYQPLGLFAPTARYGTPEDFAGFVDACHQAGIGVILDWVPAHFPTDAHGLGRFDGTALYEYEHPFEGFHQDWDTYIYNLGRSEVHGFMLASALHWLRTYHVDGLRVDAVASMLYRDYSRKEGEWLPNRHGGRENLEAIDFLHHLNQVVASETPGALVIAEESTAWPGVSRPVAEGGLGFSHKWNMGWMHDSLAYIGEDPLHRRYHHHQLTFGLLYAFSEHFILPISHDEVVHGKHSLLDKMPGDRWQKFANLRLYLSFMWSHPGKKLLFMGCEFGQWREWNHDGELDWYLLRYPEHQGVQDLVATLNRLYHELPALHARDGEALGFEWLIGDDQANSVYAWLRHAAGEPSLLAVHNFTPVPRQGYRIGVPQGGDWDVLLNSDAQAYAGSGAGSQGRVASEPAGAHGQAQSLLLELPPLGTLLLRPAG
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RS18_NITOC
Sequence: MARFFRRRKFCRFTAEGVKEIDYKDLATLKDYITETGKIVPSRITGTKAKYQRQLSRAVKRARYLALLPYCDRH
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: LUXS_SHISS
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: RBL_LUPLU
Sequence: SVGFKAGVKDYKLTYYTPDYKTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPNAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASEGNQIIREASKWSPELAAACEVWKE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y4958_ARATH
Sequence: MAAPRNLTGDGGARQLVKDEESPAASSAAKGLLNDDSPTGKRTKSERFPLSRWEFAVFFTVFLVFTTGLFCIYLTMPAAEYGKLKVPRTISDLRLLKENLGSYASEYQARFILGYCSTYIFMQTFMIPGTIFMSLLAGALFGVVRGFVLVVLNATAGACSCFFLSKLVGRPLVNWLWPEKLRFFQAEIAKRRDRLLNYMLFLRITPTLPNLFINLSSPIVDIPFHVFFLATLVGLMPASYITVRAGLALGDLRSVKDLYDFKTLSVLFLIGSISIFPALLKRKRVYE
What are the official names of this protein?
Uncharacterized membrane protein At4g09580.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FAP24_HUMAN
Sequence: MEKNPPDDTGPVHVPLGHIVANEKWRGSQLAQEMQGKIKLIFEDGLTPDFYLSNRCCILYVTEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLDLGMVLLPVASQMEASCLVIQLVQEQTKEPSKNPLLGKKRALLLSEPSLLRTVQQIPGVGKVKAPLLLQKFPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQPR
What is the function of this protein?
Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA.  Regulates FANCD2 monoubiquitination upon DNA damage.  Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.  Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
What are the official names of this protein?
Fanconi anemia core complex-associated protein 24, Fanconi anemia-associated protein of 24 kDa.
Protein: ATPA_MOOTA
Sequence: MSIRPDEITSILKNQIEQYQLEVEMAEVGTVTQVGDGIARIYGLDRAMAGELLEFPGDIYGMVLNLEEDNVGAVILGPYTHIKEGDQVKRTGRIVEVPVGEALIGRVVNAMGQPIDGKGPIQTDKFRPVESPAPGVVYRQPVNTPLQTGLKAIDSMVPIGRGQRELIIGDRQTGKTAIAVDTIINQKGQNVICIYVAIGQKASTVAGVVQRLEEAGAMEYTIVVMATASEPAPMLYIAPYAGCTMGEYFMYEQHRDVLCVYDDLSKHAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAARLNDSLGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLESDLFYAGQRPAINVGLSVSRVGGAAQIKAMKQVAGRLRLDLAQYRELAAFAQFGSDLDKATQARLARGERMMEILKQDQYQPMPVEEQVVVLYAAVNGFLDDLPVARVRAFEKDFLRFLRNERPEVLAGIREKRQLDDNLQEQLKKSIEDFKGSFTAAGES
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPL_ECO81
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU6M_ARTSA
Sequence: FLIFLGGILVMFIYVSSLSANEKFAVDLTSFMWVVPTIVLSFLVLNKNFMFMSPSS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TAL_KITKI
Sequence: MTAPHTAPARVAVLGGTGFIGRVLGARLLAQGAEVLSLARKAPAEPAPGRFVAFDLSNGDPAELTALLDRERIDTVVNAAGGMWGLNDEQMYQANVVLTERLIEAVAAMASPARLVHLGTVHEYGMAPVGTSQRESDPAAPVMEYGKLKLAATEAVVRAVEAGRISGVVLRLGNVVGAGQPGHSLLGVMAAKLDAARAAGETAQLSLQPLTALRDFVDLTDTLDAVLLAAADRSAPPVVNVGTGSASTARHLVELLIEESGVPTEITEVPAPDGTGPETEWQQLDVTVARDSLGWTPRRTLREAVRELWTAQSTAPVA
What is the function of this protein?
Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to dTDP-6-deoxy-L-talose.  Can use NAD(+) or NADP(+).
What are the official names of this protein?
dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD(P)(+)).
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: SAA_BOVIN
Sequence: MKLFTGLILCSLVLGVHSQWMSFFGEAYEGAKDMWRAYSDMREANYKGADKYFHARGNYDAAQRGPGGAWAAKVISDARENIQRFTDPLFKGTTSGQGQEDSRADQAANEWGRSGKDPNHFRPAGLPDKY
What is the function of this protein?
Major acute phase reactant.  Apolipoprotein of the HDL complex.
What are the official names of this protein?
Serum amyloid A protein, SAA.
What is the protein family that this protein belongs to?
Belongs to the SAA family.
What are the subcellular locations of this protein?
Secreted.
Protein: VG19_ICHVA
Sequence: METMGPMVKSIWFWVIVLLVSGEGTDAVEIYWLELHESAVPCYGSKNTTMGDCLLAGGILGLCGFEMLHRDTPLRRGVINKVSYRAVPRFMVFLSVMVTILHVLIITACLTIYIIAKVRSRCRRPIERTPDKPDPERVRLYLDSVRRRYWPCSGTEGDEDRTRLMPPGDRVEYDGREKLVRFSDVVTTHLLTDPGDGTYTIANE
What are the official names of this protein?
Putative membrane protein ORF19.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PHS_RICB8
Sequence: MTITCSLSDKKCIPCEGGVPPLEKKEIDKLLSELQNEWIVNESGHLYKKYKFPDFMQPIEFANKIAALAEQEVHHPDLTISWGACIVEIWTHKIDGLTESDFILAAKIDLLQN
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: PUP11_ARATH
Sequence: MAKEPVRVLVTGAAGNQEPILVKEESVVGIPTPLLKLKSWQWWVLVSVNIFFLIGGQAASVLLGRFYYDEGGNSKWMATLVQTAAFPILYIPLLLLPSSASVESSESSCSLKYIVLIYVLLGVIIAGDNMLYSVGLLYLSASTYSLICATQLAFNAVFSYFINAQKFTALILNSVVLLSFSAALIALNDDADTPSGVSRSKYIVGFVCTLAASALYSLLLSLMQFSFEKILKRETFSVVLEMQIYTSLVATCVSVIGLFASGEWRTLHGEMEGYHKGQASYVLTLVWTAVTWQVCSVGVVGLIFLVTSLFSNVISTLSLAVTPLAALVVFRDKMSGVKIMAMLIAIWGFASYVYQNHIDDLKVRQARQQAQAGRVEPPC
What are the official names of this protein?
Probable purine permease 11, AtPUP11.
What is the protein family that this protein belongs to?
Belongs to the purine permeases (TC 2.A.7.14) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: H2C01_CYRHA
Sequence: MKVTLIAILTCAAVLALHTTAAEELEAESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWECKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1w, U4-TRTX-Hhn1w, Hainantoxin-II-3, HNTX-II-3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMU_ALKOO
Sequence: MKLKAIILAAGAGTRMKSKLPKVLHKVCGRTMLNHVIDVAKGSMVQECIVVVGHGAEDVKESLTPDVKTVLQKEQLGTGHALMMAEPYIDDGTILVLCGDGPLITEETLNRTVAYHREGNFKATVLTTDLANPKGLGRIVRNAEGQLEKIVEEKDATEEEKAIIEVNSGIYCFDGEILKEALPKLKNENAQKEYYLTDILSIIRNMGFGVGVYKLEEYEEIMAVNSREQLADVEAIMRRRIAKKHMANGVTIMNPEHVYIEKTVTIGADTILYPGVILTGNTVIGEDCIIGQNSRIEDTIIGDGVEVQSSTIIHSKVGNFTHIGPYAYLRPNSNIGEHVKIGDFVEVKNSNIGDHSKASHLAYIGDADVGQNVNIGCGVVFVNYDGKNKHRTTVEDNSFVGSNSNLIAPVTVKESGYVACGSTITKDVPEGSLAVARARQENKEGWTKRKGLLKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C1C1L_HUMAN
Sequence: MVSASGTSFFKGMLLGSISWVLITMFGQIHIRHRGQTQDHEHHHLRPPNRNDFLNTSKVILLELSKSIRVFCIIFGESEDESYWAVLKETWTKHCDKAELYDTKNDNLFNIESNDRWVQMRTAYKYVFEKYGDNYNWFFLALPTTFAVIENLKYLLFTRDASQPFYLGHTVIFGDLEYVTVEGGIVLSRELMKRLNRLLDNSETCADQSVIWKLSEDKQLAICLKYAGVHAENAEDYEGRDVFNTKPIAQLIEEALSNNPQQVVEGCCSDMAITFNGLTPQKMEVMMYGLYRLRAFGHYFNDTLVFLPPVGSEND
What are the official names of this protein?
C1GALT1-specific chaperone 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: DNLJ_SYNPW
Sequence: MSIPQGLQERAAELRQLLNRAAHAYYVLDAPDLEDSVYDRLYRELLDLEAAHPELVEADSPTQRVGGSPAEGFRSVTHRIPLFSLDNAFSAEELRGWYTRLLKVLDREPPSGSPLPALAMVGELKIDGNALALSYDNGVLVRAATRGDGDQGEDITANVRTIASIPLRLHLDPPPAWVEVRGEALIPDNTFAAINSERAARDEPLFANPRNACAGTLRQLDPKVVAARRLDFFAYTLHLPEDWSGERPTSQWESLRWLEDAGFRVNPNAALLPDVDSVEQFFGDWDSRRHDLNYATDGVVVKLNDLRLQDAAGFTQKAPRWAIALKYPAEEAPSRLLKLTCQVGRTGVVTPVAEFEPVSLAGTSVSRATLHNADRLQELDLHSGDTIIVRKAGEIIPEVLRVLPELRPEGALPLELPQQCPSCGSDLVRESGEAATRCVNSSCPAILSGALRHWVSKGALDVDGLGSKLIEQLVERGLVRSIADLYRLDTALLTSLERMGEKSAGNLVAALAQSRTQPWSRQLYGLGIHHVGEVNAKALASAFADAHSLADAAVQRPEAITDLHGIGPEIAQSLQQWFNTSANQDLLQQLRAVGLTLAASDQERQALADRNNGKGHLNGQTFVLTGTLPSLSRSQAQALIEGAGGKVSGSVSKKTSFVVAGDEAGSKLDKANTLGVSVLDEAALMLLIQNSADTIHLL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RS19_FRAT1
Sequence: MPRSLKKGPFVDHHLLKKVFEAQESNSKKPIKTWSRRSMIVPDMIGLTIAVHNGQQHVPVLMTEEMVGHKLGEFVVTRNYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: STDH1_CAEEL
Sequence: MDIEWFATGVGAVVVLYILYHFIRITLNILGPYVFCQPIDLKKKAGASWAVVTGATDGIGKSYSFELAKRGFNVYIVSRTQSKLEHTKKEILEVHPDIEVRFATFDFTNPSVSDYEKLLSKLNEVSIGILINNVGMFFDYPEMLHKINGGIDSIANVTIINTLPATLLSAGILPQMVPRKAGIIVNIGSVAGLATMAEWSVYSATKKYVEWITGCLQKEYGHQGIIFQAITPAMVATKMAGNPNTSFFTPDSDTFAKSALNTIGHASQTTGYITHQIECEMLKLLPDFVIDRSIKQTSAQLREALAKNENKPLM
What are the official names of this protein?
Putative steroid dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
Protein: NTPPB_CHRSD
Sequence: MTRLVLASGSRWRRQLLDRLELPYAWAAPDIDETPHPRESPQALVHRLALGKATALAGEYPDHLIIGSDQVCLFDDQILGKPGDAATARANLQRFSGQRVRFLTGIAVIDTAHARHWVDHERYDVIFRDLSETEIAHYVDREQPLDSAGSFRMEGLGITLFERLEGRDPNTLIGLPLIRLCEMLREAGLDPLG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNF22_PONAB
Sequence: MRLAKPKAGISRSSSQGKAYENKRKTGRQRQKWGMTIRFDSSFSRLRRSLDDKPYKCTECEKSFSQSSTLFQHQKIHTGKKSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDECGESFKQSSNLIQHQRIHTGEKPYQCDECGRCFSQSSHLIQHQRTHTGEKPYQCSECGKCFSQSSHLRQHMKVHKEEKPRKTRGKNIRVKTHLPSWKAGTGRKSVAGLR
What is the function of this protein?
Binds DNA through the consensus sequence 5'-CAATG-3'.  May be involved in transcriptional regulation and may play a role in tooth formation (By similarity).
What are the official names of this protein?
Zinc finger protein 22.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DGOD_ESCF3
Sequence: MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAAVHELSDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAVDAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAEAYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFSMVGGFFKPLMKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase, GalD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.