PharMolix/UniProtQA huggingface dataset:
Protein: AC41_NPVAC
Sequence: MTMENNAEFNRRLEYVGTIATMMKRTLNVLRQQGYCTQQDADSLCVSDDTAAWLCGRLPTCNFVSFRVHIDQFEHPNPALEYFKFEESLAQRQHVGPRYTYMNYTLFKNVVALKLVVYTRTLQANMYADGLPYFVQNFSETSYKHVRVYVRKLGAIQVATLSVYEQIIEDTINELVVNHVD
What is the function of this protein?
Plays a role in late gene expression.
What are the official names of this protein?
Protein AC41.
Protein: CCL3_PANTR
Sequence: MQVSTAALAVLLCTMALCNQFSASLAADTPTACCFSYISRQIPQNFIADYFETSSQCSKPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA
What is the function of this protein?
Monokine with inflammatory and chemokinetic properties.  Binds to CCR1, CCR4 and CCR5 (By similarity).
What are the official names of this protein?
C-C motif chemokine 3, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, Small-inducible cytokine A3.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_XANCB
Sequence: MRIDVISLFPEFIAQCAAFGVVGRAQERGLLELQGWNPRDHAQGNYRRVDDRPFGGGPGMVMLIEPLRACLEAAKAADARPAPVIYLSPQGRPLTQPLARELAQLPRMVLLCGRYEGVDERFLDQAVDMEISIGDYVLSGGELGAAVLVDVVTRLQDGVLNDAESAAQDSFEGPQGLLDCPHYSHPSSHAWGDVPEVLRSGNHGAIARWRRQQSLGRTWLRRPELLDEATLDKQDRRLLEEFRRELAPGDEK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_BACLD
Sequence: MDYKDTLLMPKTDFPMRGNLPNREPEIQGKWEDMDIYSLVQKRTEGRPMFVLHDGPPYANGDIHMGHALNKVLKDFIVRSRSMSGYHAPYVPGWDTHGLPIETALTKNKKVKRKEMTVAEFRKLCEEYAWQQIEGQKAQFKRLGVRGDWENPYVTLKPEFEAQQIKVFGEMAKKGYIYKGKKPVYWSPSSESALAEAEIEYHDKRSPSIYVAFDVKDGKGVLTNGEKIVIWTTTPWTIPANLGIAVHPELEYSVVAAGGARYVMASALIESVAKAIGFEDHEVVQTVKGKDLEHIVAVHPLYGRDSLVMLGEHVTTDAGTGCVHTAPGHGEDDFIIGQKYGLDVLCPVDEKGHMTSEAPGFEGLFYDQANKPITEQLEEKGALLKLDFITHSYPHDWRTKKPTIFRATAQWFASIKDFRDELLEAVKKTKWVPEWGETRLYNMIRDRGDWCISRQRAWGVPIPVFYAENGEPIITDETINHVSELFREHGSNIWFEKEANELLPEGFTHPGSPNGKFTKEQDIMDVWFDSGSSHQAVLEEREDLVRPADLYLEGSDQYRGWFNSSISTAVAVTGKAPYKGVLSHGFALDGEGRKMSKSLGNVVVPAKIMNQFGADILRLWVASVDYQADVRVSDAILKQVAEVYRKIRNTFRFLHGNIADFDPAKDAIAVEDLREVDQYILIKLNSLIEKVKKAYEEYDFAVIYHAVHNFCAIELSSFYMDFAKDVVYIEHADHKDRRSMQTVFYETLLALVKLIAPILPHTADEMWSHFTFVSEKSVQLTDMPETRDIPNAKETEEKFDSFMKLRDDVLKALETARNEKIIGKSSVASLTLYPNEEAKALLSSIKEDVKQLFIVSELAIGGTEADAPEDAQSFETGKIVVAQAEGETCERCRMVSKEIGEDPDHPELCPRCAGIVKTYYQN
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_SALPA
Sequence: MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILAPLIEAGVTLLPNTSGAKTAEEAIFAAQLAREALGTHWLKLEIHPDARWLLPDPIETLKAAEALVKQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETKAMLEIIIQQATVPVVVDAGIGVPSHATQALEMGADAVLVNTAIAVADNPVMMATAFRLAVEAGLLARQAVPGNRSTYASATSPLTGFLEALA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTSB_METMA
Sequence: MIRHIDIAVQKIFEMKEKEPAKFKKLIDEGIMIGLGVDLGDRSREEYTAGHIKEQSRPKDPDYAAVTEAVIEGDSEETVRLTVALLEKGKDPTDLVLNALMPGIQTVCELYDIGESYMPEILLANEALIGGVKLCQERIGEIRYEGKVVSLVIEGDLHDIGKNIVAAILRANGFEVVDLGNDITVEAAVKAVKAANADLVVGTTLMSTTKEGLKVLAEVLESEDVPVACGGAAVDRRFVETFCNSVYGKTPLDAVKIAKNICAGKSWKEVRNDLH
What is the function of this protein?
Harbors a corrinoid prosthetic group and acts as a methyl group carrier in methanogenesis from methylated-thiols.
What are the official names of this protein?
Methylated-thiol--corrinoid protein MtsB.
What is the protein family that this protein belongs to?
Belongs to the methylamine corrinoid protein family.
Protein: SPX3_ORYSI
Sequence: MKFGKRLKKQVEESLPEWRDKFLAYKRLKKLVRLVSSSSGDVGGGGGGEAEFVRLLDGEVDRINAFFLEQEEEFVIRQRELQETVEKVAGGGGGGRRPAAAEMRRVRKEIVDLHGEMVLLLNYSAVNYTGLAKILKKYDKRTGRLLRLPFIEKVLRQPFFTTELISRLVRDCEATMEAIFTSSVATTAMAGDRRTWKGCSGDAGMAPMADQQGIFRNTVAALATMKELRSGSSTYGRFSLPPMAAPASPESDVLQSIRSDPHLKENGRIPSLQFFYA
What are the official names of this protein?
SPX domain-containing protein 3, Protein SPX DOMAIN GENE 3, OsSPX3.
Protein: NUON1_SOLUE
Sequence: MPVSPAFNPQDALRFLPEIILTVMGTLLMVLDPVIHKRSSNAFGHISLIALVMALGASIYAYGIAGPAFGGMLMVDGFATFFRVVVITVGILTVFPSYRFLARQDAETSEYHALLLFSIAGQCLMAASNDLIMVFIGLEISSIASYVLAGYLRDDKRANEAALKYFLLGSFATGFFLYGVAWIYGLTRSVNLSVVRGVFQHQPVDPTFVGIAAALMFVGLAFKVSAAPFQIWAPDVYQGAPTPVSAFLSAGPKAAAFAIFLRIFMTAFEPISDKWQPLVWTAALASMCIGNFAAILQTNIKRMLAYSSIAHAGYVLVALTAHSETGVAAAMFYLAGYAFMNVGAFAAVSVLTGKGERYQNIDDFKGMGRKQPLAAAMFTIFLLSLLGVPLTGGFFGKFYIFKAALDSHLIWLTVLGLLNSAVGAYYYLRILVVMYMYEPGEAADAAEPLAPSLAFALILPALGTLALGIFPGWVLEFATKSAANLK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 1, NADH dehydrogenase I subunit N 1, NDH-1 subunit N 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSHC_RHOE4
Sequence: MQSWSDTALPSVPGQGPPLRLYDTADRQVRPVTPGKKATMYVCGITPYDATHLGHAATYLTFDLVNRIWRDAGHDVHYVQNVTDVDDPLFERANRDGEDWIVLGIRETALFREDMEALRVLPPKDYIGAVESVNEVVELVEKFVASGAAYIVDDAEFPDVYFRADATEQFGYESGYDRATMEKFFAERGGDPDRVGKRNPLDALVWRAERPGEPSWPSPFGPGRPGWHIECAAIALNRIGSGFDVQGGGSDLIFPHHEFSAAHAESATGDRRFARHYVHTGMIGLDGEKMSKSRGNLVFVSKLRGEGVDPAAIRLGLLSGHYRQDRAWTDQVLEDAQSRLKVWREAAALDSAPSATDTVARLRQHLADDLDTPKALDALDGWARRAIEGGGSDTQAPGEFADAVDALLGISLR
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: GNGF_STRP3
Sequence: MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGELRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNESDGALAGHPLGNLIIAGISEMQGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYQGMIDHVYVTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVVYICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLVQVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ
What is the function of this protein?
Required for morphogenesis under gluconeogenic growth conditions.
What are the official names of this protein?
Putative gluconeogenesis factor.
What is the protein family that this protein belongs to?
Belongs to the gluconeogenesis factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_HAEDU
Sequence: MNNCTPNIKSSYGYEDLLASGRGELFGKEGPQLPAPTMLMMDRVNLMTENGGLFDKGYIEAELDIHPDLPFFGCHFIGDPVMPGCLGLDAMWQLVGFFLGWIGGKGKGRALGVGEVKFTGQILPTAKKVTYRIHMKRVINRKLVMGLADGEVEVDGRVIYTATDLKVGLFQDTSSF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBJ_NEOYE
Sequence: MAGTGRIPLWLVATVGGIAAITVLGIFIYGSYSGVGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MTRD_METTH
Sequence: MDPLLLIGAITAGGVLIGGGVHFVPVGGAPAAMATATGVGTGTAMLAAGAGLTGLITAAAMTGQSPLMIMAAGAVGSMLMIGITMLVGNLIYVYGVGTVPVSAKVAVDPLTGMEQEKYVTPGTEGHGLPTVCFVSGIIGGALGGIGGGLIYWALNEALKTLSYGAIGAAGVAAIFAVGIFFINAVIASYNIGGTIEGFHDPKFKRIGRGIVACLIASIVAGALSTLLVYGGVF
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit D, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit D.
What is the protein family that this protein belongs to?
Belongs to the MtrD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BDF1_YEAST
Sequence: MTDITPVQNDVDVNGNNVNDDVSSNLKRPIDQGDPSNGLAEEENPANNQLHLKKARLDGDALTSSPAGLAENGIEGATLAANGENGYNATGSGAEDEQQGLKKEEGGQGTKQEDLDENSKQELPMEVPKEPAPAPPPEPDMNNLPQNPIPKHQQKHALLAIKAVKRLKDARPFLQPVDPVKLDIPFYFNYIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFEKHMLNMPAKDAPPVIAKGRRSSAQEDAPIVIRRAQTHNGRPKRTIHPPKSKDIYPYESKKPKSKRLQQAMKFCQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFERDVRLVFKNCYTFNPDGTIVNMMGHRLEEVFNSKWADRPNLDDYDSDEDSRTQGDYDDYESEYSESDIDETIITNPAIQYLEEQLARMKVELQQLKKQELEKIRKERRLARGSKKRGKRSKGRSGSKNASSKGRRDKKNKLKTVVTYDMKRIITERINDLPTSKLERAIDIIKKSMPNISEDDEVELDLDTLDNHTILTLYNTFFRQYESSSGASNGLDGTSGVTRDASSLSPTSAGSRKRRSKALSQEEQSRQIEKIKNKLAILDSASPLSQNGSPGQIQSAAHNGFSSSSDDDVSSESEEE
What is the function of this protein?
Transcription factor involved in the expression of a broad class of genes including snRNAs.  Required for sporulation and DNA-damage repair.  Prevents the spreading of SIR silencing at telomeres and protects histone H4, but not H3, from deacetylation.
What are the official names of this protein?
Bromodomain-containing factor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATS8_MOUSE
Sequence: MLRDPTTTGWPPLLLLLLQLPPPPLVCGAPAGPGTGAQASELVVPTRLPGSASELAFHLSAFGQGFVLRLAPDASFLAPEFKIERLGGSSAAAGGEPGLRGCFFSGTVNGERESLAAMSCVAGWSGSFLLAGEEFTIQPQGAGDSLDQPHRLQRWGPGQRREDPGLAAAEVFPLPQGLEWEVEMGNGQGQERSDNEEDRKQDKEGLLKETEDSRKVPPPFGSKTRSKRFVSEARFVETLLVADASMAAFYGTDLQNHILTVMSMAARIYKHPSIRNSVNLVVVKVLIVEKERWGPEVSDNGGLTLRNFCSWQRRFNKPSDRHPEHYDTAILFTRQNFCGKGEQCDTLGMADVGTICDPDKSCSVIKDEGLQAAYTLAHELGHVLSMPHDDSKPCVRLFGPMGKYHMMAPFFIHVNKTLPWSPCSAVYLTELLDDGHGDCLLDAPTSVLPLPTGLPGHSTLYELDQQCKQIFGPDFRHCPNTSVEDICVQLCARHRDSDEPICHTKNGSLLWADGTPCGPGHLCLDGSCVLKEDVENPKAVVDGDWGPWRPWGQCSRTCGGGIQFSNRECDNPMPQNGGRFCLGERVKYQSCNTEECPPNGKSFREQQCEKYNAYNHTDLDGNFLQWVPKYSGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPDTLSICVRGQCVKAGCDHVVNSPKKLDKCGVCGGKGTACRKISGSFTPFSYGYNDIVTIPAGATNIDVKQRSHPGVRNDGSYLALKTANGQYLLNGNLAISAIEQDILVKGTILKYSGSMATLERLQSFQALPEPLTVQLLTVSGEVFPPKVRYTFFVPNDMDFSVQNSKERATTNIIQSLPSAEWVLGDWSECPSTCRGSWQRRTVECRDPSGQASDTCDEALKPEDAKPCGSQPCPL
What is the function of this protein?
Has anti-angiogenic properties.
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 8, ADAM-TS 8, ADAM-TS8, ADAMTS-8, METH-2.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HMX2_MOUSE
Sequence: MGSKEDVGKGCPAAGGVSSFTIQSILGGGPSEAPREPAGWPARKRSLSVSSEEEEPEEGWKAPACFCPDPHGPKEPSPKHHTPIPFPCLGTPKGSGGAGPAASERTPFLSPSHPDFKEEKERLLPAGSPSPGPERPRDGGAERQTGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVGMPLVFRDSSLLRVPVPRSLAFPAPLYYPSSNLSALPLYNLYNKLDY
What is the function of this protein?
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development.
What are the official names of this protein?
Homeobox protein HMX2, Homeobox protein Nkx-5.2.
What is the protein family that this protein belongs to?
Belongs to the HMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: K2C8_DANRE
Sequence: MSTYSKKTSYTVKSSSSGSIPRNFSSLSYSGPSMSRQSYSARSSYGGVNRGMGAGMGGGSGFISSSSAYGLGMGMGTGMGAGVVAPIQAVTVNKSLLAPLNLEIDPNIQIVRTQEKEQIKTLNNRFASFIDKVRFLEQQNKMLETKWSLLQNQTATRSNIDAMFEAYIANLRRQLDSLGNDKMKLEADLHNMQGLVEDFKNKYEDEINKRTECENEFVLIKKDVDEAYMNKVELEAKLESLTDEINFLRQIFEEEIRELQSQIKDTSVVVEMDNSRNLDMDAIVAEVRAQYEDIANRSRAEAEMWYKSKYEEMQTSANKYGDDLRSTKTEIADLNRMIQRLQSEIDAVKGQRANLENQIAEAEERGEMAVRDAKGRIKDLEDALQRAKQDMARQIREYQDLMNVKLALDIEIATYRKLLEGEEDRLATGIKAINISKQSTSYGGYPMESAGSSYSTYSSGYSSGLSGGYGGGYSGGYSGGYSSGSGYSDTVSQTKKSVVIKMIETKDGRVVSESSEVVQD
What is the function of this protein?
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
What are the official names of this protein?
Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
Protein: OBG_ALIF1
Sequence: MKFVDEATIKVDAGDGGNGVVSFWREKFVAKGGPDGGDGGDGGDVYLEADENLNTLIDYRFNRFYNAERGKNGSGGNCTGKRGEDITLKVPVGTRAIDIDTGEKVAELMTHGMKQMVAKGGWHGLGNTRFKSSVNRAPRQKTLGTKGEVRELRLELLLLADVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLIPSLGVVRARGNKSFVVADIPGLIEGAADGAGLGVRFLKHLERCRVLLHVIDILPIDGSDPVQNALTIIDELEQYSEKVASKPRWLLFNKTDLLLEEEADEKINEILEALAWEDRYFKIAAVSRTGTQELCDELADFMDTLPKEIQTEEEKAANKVDFMWDDYHKDAMSGKDVVTEDDWDDWDDEEDDGHVIYVRD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP12_BPAPS
Sequence: MRVAITEGPSPCTALIRFQPKSFITFYKHQTFFTDMHYNTFIAYRFFSSASCRCDLRPDNQSLHWLATNNPLSIPETAAVHVLPRQAWRTLMRPEENGKNLFGDIAPAAGPL
What are the official names of this protein?
Putative protein p12.
Protein: PPIL1_NEUCR
Sequence: MATDVAVETTMGTFTLELYTNHAPKTCKNFATLADRGYYDSTVFHRIIKDFMIQGGDPTGTGRGGSSIYGEKFEDEIHPGLKHTGAGVLSMANAGPNTNGSQFFITLAPTPWLDGKHTIFGRVKKGMGVIRRMGMVPTDKEDRPATEVKIVKARVVREEDMEA
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 1, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.
Protein: RL332_MYCGA
Sequence: MRKKIILICEHCLNRNYTTTRSKLETTRLVLNKYCSSCNQKTVHKESH
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NDK_RHIE6
Sequence: MAIERTFSMIKPDATKRNLTGAITKMLEDAGLRVVASKRVWMSRREAEGFYAVHKDRPFFGELVEGMTSGPTVVQVLEGEGAILKNREIMGATNPANADEGTIRKVHALSIGENSVHGSDAPETAAQEIKYWFSDTEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADB_RHIME
Sequence: MLTDHFRPQSFNGIDDIVIVGGGLAGLFCALKLAPRPVTILAAAPIGYGASSAWAQGGIAAAMSKGDTFEKHVADTVAAGAGIVDEKMTRMMVAEGPARIHDLLEFGVPFDRDLEGKLLLSREAAHSERRIVRVKGDMAGKSIMEALIAAVRNTPSIRVIEGYVVEELVREGRFISGVIARPDAGQSKSRVSFPARAVVLCSGGVGHLYAVTTNPWEACGQGVGMAARAGAIIADPEFVQFHPTAIDIGKDPAPLATEALRGDGATLINSEGRRFMLDIHPDGELAPRDIVSRGVFAEVQAGRGAFLDCTKAVGRHFPEMFPTVYASCMAAGIDPVRQPIPVTPAVHYHMGGVLTDGEGRTSIDGLWAAGEVTSTGVHGANRLASNSLLEAVVFAARIAENIKGSLPAPKLTAWGDNAGENDDPVTVEDSPPFKVLRQLMSDCVGVVRTRESLTRAIRGIAELERTNKRLRFANIATTAKLIAIAALQRTESRGGHFRADCPDERPEWRRRTYLTLAQAERLAAEVAESEPA
What is the function of this protein?
Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
What are the official names of this protein?
L-aspartate oxidase, LASPO, Quinolinate synthase B.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUKL2_STAAS
Sequence: MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKEKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNPKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKEGQRLIVTYEVDWKNKTVKVVDKYSDNKSFREG
What are the official names of this protein?
Uncharacterized leukocidin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: VGLU1_MOUSE
Sequence: MEFRQEEFRKLAGRALGRLHRLLEKRQEGAETLELSADGRPVTTHTRDPPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGVFASGEKQPWAEPEEMSEEKCGFVGHDQLAGSDESEMEDEAEPPGAPPAPPPSYGATHSTVQPPRPPPPVRDY
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate (PubMed:29642010, PubMed:25433636, PubMed:33440152, PubMed:29273736).  At the synaptic vesicle membrane, mainly functions as an uniporter which transports preferentially L-glutamate but also phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:25433636, PubMed:29642010, PubMed:15103023, PubMed:15118123).  The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane (PubMed:29642010).  In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane that affects the proton electrochemical gradient and promotes synaptic vesicles acidification (PubMed:25433636, PubMed:29273736, PubMed:29642010).  Moreover, may function as a K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular glutamate uptake (By similarity).  The vesicular K(+)/H(+) antiport activity is electroneutral (By similarity).  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation (PubMed:33440152, PubMed:29642010).  The symporter activity is driven by an inside negative membrane potential and is electrogenic (PubMed:29642010).  Is necessary for synaptic signaling of visual-evoked responses from photoreceptors (PubMed:17611277).
What are the official names of this protein?
Vesicular glutamate transporter 1, VGluT1, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: FAR8_TYRGL
Sequence: ARSDNFVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-8, FMRFa-8.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NKX25_CHICK
Sequence: MFPSPVTTTPFSVKDILNLEQQQQGGLAPMELSSPSCMLATFKQEAFGSEPPALPELPEPPPAKPPAAFPGPYYVKSYGEMDTAKDSKADKKELCALHKSLEQEKRELEDPERPRQRKRRKPRVLFSQAQVYELERRFKQQKYLSAPERDHLANVLKLTSTQVKIWFQNRRYKCKRQRQDQTLEMVGIPPPRRIAVPVLVRDGKPCLGESSPYSSPYNVSINPYSYNAYPAYPNYNSPACNANYNCSYPAVQPVQPSAAGNNFMNFSVGDLNSVQPPIPQGNAGISTLHGIRAW
What is the function of this protein?
Transcription factor required for the development of the heart and the spleen.  Implicated in commitment to and/or differentiation of the myocardial lineage.  Binds to the core DNA motif of promoter.
What are the official names of this protein?
Homeobox protein Nkx-2.5, cNKx-2.5, Homeobox protein NK-2 homolog E.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIP11_MAGO7
Sequence: MAEQLILKGTLEGHNGWVTSLATSMENPNMLLSSSRDKTLIIWNLTRDETSYGYPKRSLKGHSHIVSDCVISSDGAYALSASWDKTLRLWELATGTTTRRFVGHTNDVLSVSFSADNRQIVSGSRDRSIKLWNTLGDCKYTITEKGHSEWVSCVRFSPNPQNPVIVSSGWDKLVKVWELSSCKLQTDHIGHTGYINTVTISPDGSLCASGGKDGTTMLWDLNESKHLYSLNANDEIHALVFSPNRYWLCAATASSIIIFDLEKKSKVDELKPEFAAVGKKSREPECISLAWSADGQTLFAGYTDNIIRAWGVMSRA
What is the function of this protein?
Involved in regulating the cell wall integrity and MPS1 activation via its interaction with the MAPKKK MCK1.
What are the official names of this protein?
MST50-interacting protein 11.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.