PharMolix/UniProtQA huggingface dataset:
Protein: ENDA_SULIK
Sequence: MVKALLVGSKVLIPNVDESRYIYSNGFYGKAIGISKPKGPKDIIRPLELSLIESVYLAKKGLIKVIDKNGEVLEYEKLYEYSSKIINKFDIMYRVYEDLREKGFIVRSGVKYGADFAVYTLGPGLEHAPYVVIAVDIDEEITPHELLSFGRVSHSTRKRLVLALVDRKSESVRYIMFKWVKM
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
Protein: RS17_SHEB9
Sequence: MSDKIRTLQGRVTSNKMDKSITVAIERQVKHPIYGKYIKRTTKIHAHDETNQCNEGDLVAIRECRPLSKTKSWTLVEVVSKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RDRP_ISAV8
Sequence: METLVGGLLTGEDSLISMSNDVSCLYVYDGPMRVFSQNALMPTLQSVKRSDQFSKGKTKRFIIDLFGMKRMWDIGNKQLEDENLDETVGVADLGLVKYLINNKYDEAEKTSLRKSMEEAFEKSMNEEFVVLNKGKSANDIISDTNAMCKFCVKNWIVATGFRGRTMSDLIEHHFRCMQGKQEVKGYIWKHKYNERLKRKQLSKEEVKFDREEYTSRSFRLLSFLKNSERTKLEPRAVFTAGVPWRAFIFVLEQTMLVVNKLDPNSVIWMGSDAKINTTNSRIKEIGMKNQGQTLVTLTGDNSKYNESMCPEVMMVFLRELGIKGPMLEVLDYALWQFSQKSVKPVAPIKKRTGKSTVVIKADSVKECRDAFNEKELELIQGVEWMDDGFVRVRRGMLMGMANNAFTTASTIASSFSFTPEAVYTLQSSDDFVTGSCGRDVQHARQRLEMALKVSKAAGLNVSQKKSFYVEGTTFEFNSMFVRDGKVMANGGNFENMTVPGGLGPSTDLFVVGKQARNSMLRGNLSFSQAMEMCKIGITNVEKVYYGNRKYQELKNEIREKCGEETMSIPESMGGDRKPRPWELPQSFDGIALKEAVNRGHWKAAKYIKSCCSIEFDEEGDQSWDTSKTALVVIRKNETDMRRRTVKTRNPKDKIFNDAMNKAKRMYETVVDRNPLLGLKGKGGRLTVKDLKARKLIDEVEVVKKKKHV
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus segments.  Binds the promoter sequence of the encapsidated viral RNA.  Displays an endonuclease activity involved in cap-stealing.  Cleaves cellular pre-mRNA to generate primers for viral transcription (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, Protein 1, P1, RNA-directed RNA polymerase subunit P1.
Protein: VP7_ROTBS
Sequence: MVCTTLYTVCVILCILLMYIILFRKMIHFLIDLSLIAFVISSCIRLSNAQFFANDMLYNGNVEGVINTTNIFNVESLCIYFPNSAVGRPGPGKSDGLINDNNYAQTLAVLFETKGFPKGSVNFNTYTKISDFINSIEMTCSYNIVIIPETLANSETIEQVAEWVLNVWKCDNMNVDIYTYEQIGKDNFWAAFGEDCDVAVCPLDTTMNGIGCTPASTETYEVLSNDTQLALIDVVDNVKHRIQLNQVTCKLRNCVKGEARLNTAIVRISNLSSFDNSLSPLNNGQKTRSFKINAKKWWKIFYTIIDYINTFIQSMTPRHRAIYPEGWMLRYA
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: RL28_LIMF3
Sequence: MAKDFITGKRTQFGNKRSHALNSSRRSWKPNLQKATILVNGKPKKVYVSARTLKSGKVTRVN
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: WECG_ECO57
Sequence: MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAINAEKMLTIEENAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMARAGKEGTTVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASGAQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWLYRLLSQPSRIKRQLRLLRYLRWHYTGNL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: EX7S_GEOSL
Sequence: MAVEKFETALKKLEDVVRKLEGGDLSLDDSLKAFEEGVKMASFCTKKLDEAEKKVELLLKKKDGTFVREDFRLDDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2290_PAESJ
Sequence: MMTGELILVGLIVIGLIGRSPIIATAACVLLAVKLLHLSRFLPSIERRGLELGLLFLTLSVLVPFASGKVQMKELIAAFNTWPGWLALIGGAVAAYMNAKGLDLLKLDPQMVVGLVIGSIFGIIFLRGIPVGPLMAAGITAILYKLFKLMSGG
What are the official names of this protein?
UPF0756 membrane protein Pjdr2_2290.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAN5_ORYSJ
Sequence: METSYREEEARRKASLLHCIFFFLLGALAMAAAIAVLHESSYWEWRCNRLTDIVVDGDDGDGPSSSEVVDGGGEWGMVRTRGAQFVVGGGRPFYVNGFNTYWLMVLAVDPSTRGKVTEVFRQAAAVGLTVCRTWAFNDGGWRALQKSPGVYDEEVFKALDFVVSEARKHKIRLILPLINNWDDYGGKAQYVRWAQAAAAGAGADAFFSDETVRGYFKSHVTAVLTRVNAYTGVAYRDDPTIMAWELMNEPRCASDPTGDTLQAWIAEMAFHVKSVDPAHLLGVGAEGFYGPSSPPARLRVNPNADVALAGADFVRNHRVLGVDFASVHVYPDTWLPAGATKEAQLRFATSWVEAHIADAEGALGGMPVLFAEFGVSTRGARAAFNATSRDAFIEAVYGAMLRSTRRGGGGAGALLWQVFPEGTDYMDDGYAVVLPRAAATAGIVAAHSRRLQSFNSRCAWSCRWGCNKRDNDTAETTTAEADVDVSFHHEL
What are the official names of this protein?
Putative mannan endo-1,4-beta-mannosidase 5, Beta-mannanase 5, Endo-beta-1,4-mannanase 5, OsMAN5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUTA_BRASB
Sequence: MDLGVFIPIGNNGWLISTASPQYKPTFELNKQIVQRAEHYGFEFALSMIKLRGFGGKSEFWDYNLESFTLMAGLAAVTSRIKLFASTAVLTLPPAIVARMATTIDSISGGRFGINIVSGWAKAEYEQMGLWPGDDYFGYRYAYSTEYVQVMQELWRTGASDFKGKYFQMTDCHMKPLPAHKIEIVAAGQSPTGMAFAATYADYNFVLASGVNTPTAHVKLNEQLLDAVAKTGRDVGAYVLFMVIADETDEAAMAKWQAYKDGTDVDALVWMADQGSKDQSAAGSSTAKTINLPEQALNFNMGTIVGSYATVARLLDEAASVPGTKGLMLTFDDFVQGIESFGQHVQPLMTSRAARLLPAA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: NFUA_SALNS
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: MNMC_ECOLC
Sequence: MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLGGNQLEVRFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQARLQRLHFISFEKFPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDEGRVTLDLWFGDINELTSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRRGLQEAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSAPWFNRTGSSKREAAIIGGGIASALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVATNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQNLSRKDDCWLLNFAGDQQATHSVVVLANGHQISRFSQTSTLPVYSVAGQVSHIPTTPELAELKQVLCYDGYLTPQNPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKEARCGVRCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALGSRGLCSAPLCAEILAAQMSDEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_GEMAT
Sequence: MPDAMSAGAILRALLPEMLLSGGAMLLLLASVWTPQGNQPGAAEGAERTSVLARFGVILCLVVGLAVVIAWGDGAAGTPDGRVAGDGFRWAVDLVILLGTALALMLLEAEHQRSAAFGPEVPSLMLLASTGMMVLAGARDLMFVFLGVELMSLAVYVLAGVNRRSARSAEAAVKYFLLGAISSGFLLYGMALLFGATGSTRLQDITEWAAAQATLSPLFMSGVALLLVGLAFKVAAAPFHLWTPDVYDGAPLPVTAFMSATVKTAAFAVFARIMIEGLAVAAPRWHMGLWWLAAVTMVVGNVFALSQRNLVRMLAYSSIAHAGYLLVSIIVGDAAGTSALIFYVVSYTLATMGAFGVLITINGGRDRAPTLDDIAGLWLVRPWLAIAMTVFLLAFMGMPVLGGMGFFAKWYILQAALQAPAPQTILAVVLVIASAVSAAYYLAVVSAMFMRPRPEGQPVPSTTPLNQSLIATAAVALLVFGLYPTPIMELARRATTTTSPTSNPAAPRGEVRLQTASVPR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDH_XANC5
Sequence: MKAPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLELPIEKAQAALKGVMMELEDCAFPLLAGMVGTDDAEVAFKDVDIALLVGSRPRGPGMERKDLLLANAEIFTAQGAALNKVAKRDVKVLVVGNPANTNAYIAMKSAPDLDPKNFTAMLRLDHNRALSQLSAKLGKPVAGIEKLAVWGNHSPTMYPDYRFATADGASVGDAINDQEWNASTFIPTVGKRGAAIIEARGLSSAASAANAAIDHIRDWVLGTNGKWVTMGVPSDGSYGIPEGVMFGFPVTTENGKYTIVKDLPIDDFSQKYIDKTLAELEEERSGVAHLLG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: MENE_LACLA
Sequence: MKWLKKQAELYPQKQFLNDSTFAQINQEVNKMAEHLAPLIDNQSRVALLSENSVEMAVVLFALLGLSKEVLLLNRHLTEYELADQIKELKIDKVFTSDLLTEKVTDSISFSEIWTSNPCPVSLSADFPDEKIAVIMNTSATTGKFKSVPITWGMISNHVKASKETLGAYDNDNWLVILPMFHVSGLSIIMRTLYNATSATVVDKFDENQLLEMINSGKINMVSLVPTLLTRIADKLHSNNLRLILLGGEFIPQPLIKKCQELGLPIYKTYGMTESFSQSVTFNILDFPDKTSSVGRPLPGVEIEIRQADLAGVGEIWLKSPMLMKAYLGQKPYGTAFETGDIGYLDTDGFLYLLNRRKDIIISGGENIYPKEIEDLVYSLPEIKECALVAKPDAKWGQVPILFVSGNISQEKLENFLTEKLAKYKRPQSITFMDELPKNASGKILRKELKG
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: MMAD_CHICK
Sequence: MANVLCNRARLVTYLPGFYSLVKRVVNPKAFSTAGSSGSDEPHVAATPPDLCPRTVWPDEVMGPFGPQDQRFQLPGNIGFDCHLNGTAAQRKSQASKSLPDILAEPSPNERHEFVMAQYINEFQGSDVPQKQQVNNAETYFENAKVECAVQACPELLRKDFESMFPEVNANHLTVLTVTQKTKNDMTVWSQEVEDEREMLLENFINGAKEICYAICSEGYWADFIDPSSGLAFFGPYTNNTLFETDERYRHFGFSVDDLGCCKVIRHNIWGTHVVVGSIFTNAEPDSPIMRKLSGN
What is the function of this protein?
Involved in cobalamin metabolism and trafficking.  Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl).  Promotes oxidation of cob(II)alamin bound to MMACHC.  The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
What are the official names of this protein?
Cobalamin trafficking protein CblD, CblD, Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: PORB_METTH
Sequence: MKIPEEEFLAPGHRGCAGCGATVGVRLALKVLGKNTVAVSSTGCLEVITTPYPETAWRIPWIHVAFENAAAVASGVERALKAKGRDDVNVVAFAGDGGTADIGLQALSGAMERGHNIIYICYDNEAYMNTGIQRSASTPYGASTTTSPHGKESFGEDRPKKNMPLIMAAHGVPYVATASISYPEDFMEKVRKAKETDGPAYIHLHQPCTTGWGFDPAKTVELGRLAVETGSWILYEIEDGDFRVTYRPVQRKPVEEYLNAQKRFRHLTEEQKARIQEYVDSVCQELRI
What are the official names of this protein?
Pyruvate synthase subunit PorB, Pyruvate oxidoreductase beta chain, POR, Pyruvic-ferredoxin oxidoreductase subunit beta.
Protein: MES9_ARATH
Sequence: MKHYVLVHGGCHGAWCWYKVKPMLEHSGHRVTVFDLTAHGVNMSRVEDIQTLEDFAKPLLEVLESFGSDDKVVLVAHSLGGIPAALAADMFPSKISVAVFVTSFMPDTTNPPSYVFEKFLGSITEEERMDFELGSYGTDDHPLKTAFLGPNYLKNMYLLSPIEDYELAKMLMRVTPAITSNLTGTKSLTAQGYGSISRVYIVCGEDKGIRVDFQRWMIENSPVKEVMEIKDADHMPMFSKPHELCDRLLKIADKYP
What is the function of this protein?
Methylesterase shown to have carboxylesterase activity, methyl indole-3-acetic acid (MeIAA) esterase activity, methyl salicylate (MeSA) esterase activity and methyl jasmonate (MeJA) esterase activity in vitro.  Required to convert methyl salicylate (MeSA) to salicylic acid (SA) as part of the signal transduction pathways that activate systemic acquired resistance in systemic tissue.  MeSA is believed to be an inactive form that needs to be demethylated to exert a biological effect.
What are the official names of this protein?
Methylesterase 9, AtMES9.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Methylesterase family.
Protein: RRF_AERHH
Sequence: MINEIKNDAKDRMAKSVESLKTQMSKIRTGRAHPSLLDGIQVEYYGAATPLKQLANVVAEDARTLSISIFDRSMIQAVEKAILTSDLGLNPSSNGQTLRVPLPPLTEERRRDLTKIVRAEAEGARVAVRNIRRDANADLKALLKDKEISEDDDRRAQEEIQKLTDSFIKLVDEALALKEKELMEI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_CLOB8
Sequence: MRMRKKPWARPELEGCDFFVINPKEYKGKWKEFFGNDKPIYLELGCGKGTFMAVHASENPDINYIAIDIKDEVLGLAKRNIEKAYEEKNRKTDNVKLMAQEIGLISEILSEEDVVSRIYINFCNPWPKEKHKKRRLTHMRQLEQYKTFLKSEGEIYFKTDDDELFEESLEYFNEAGFRIKYITYDLHNSDVEGNVQTEHEKMFSEQGIKIKFLIAMKDN
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RNY_OCEIH
Sequence: MDIVIVVISILLALIVGIVVGYLVRRSIAEAKISSAERLAKQIVEEAHRNADAAKKEALLEAKDETHKFRQQAEDEIRERRMEAQKQENRLMQKEENLDRKSETLDKRESSLESKEQSLTEQQQQIEEMKSKVEAMKDEQQAELERISGYTSEQAKQIILERIEKEVQHESAVLIKESETRAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARMALEKLVQDGRIHPARIEEMVEKSRREVDEYIREVGEETTFEVGVHGLHPDLVKILGRLKYRTSYGQNGLKHSAEVAYLSGLLAAELGEDVTLARRAGLLHDIGKAIDHEVEGSHVEIGKELAMKYKEHEVVINSIASHHGDEEATSIIAVLVAAADALSAARPGARSETLENYIKRLEKLEEISESFDGVEKSFAIQAGREIRIMVRPDEIDDIESISIARDIRKRIEGELDYPGHIKVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YIDC_METC4
Sequence: MGNDKTNMFVAIALSLVVLLGWHYFVTGPASERQRQAAQSQAAQTGAPQTADGIPSPSPREGSPNAPAPGTLPGAAAQGPVSREDALARSARVRIDTPALYGSIGLKGARIDDVSLKNYHETVSDESPRIVLLSPTGSANPYYAEFGWVGANAGPLPNADTLWKADGDLLAPGRPLTLTWDNGQGLVFKRIVAVDDKFMFTVRDEVENTSANPVTLYPYSLVSRWGKPQTQGYYVLHEGLIGVLGGDGLQEYTYDKVGKEPAYGGAATQGKAWTNVTGGWVGITDKYWAAAAIPEQDKPFTGAFTERTDGATKIYQTSVRGDAVTLAPNASSVTTQRLFAGAKEVNRINAYEREFGIKQFDLMIDWGWFWFLTKPMFRALDFFFHLLGNFGVSILLVTLILKLFFLPIANRSYVSMAKMKAVQPEMTSIRERYKDDRVKQQQAMMELYKKEKINPVAGCWPVLIQIPVFFALYKVLFITIEMRHAPFFGWIQDLAAPDPTSIVNLFGLLPFTPPEYIPIHLGVWPIIMGITMFIQMKMNPAPPDPVQAQVFAFMPIVFTFMLGSFPAGLVIYWAWNNTLSVIQQYVIMRRNGVKVELWDNLRGMFKRGNKSAAAKG
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FBK95_ARATH
Sequence: MSSPIIIRAPKKQPPEPPCLISLLPEEIVVDIVARVPRCYYPTLSQVSRRFRSLVASPEIYKRRSFFGCTEQCLYIAISKDQTSDIHWFTLCRKPNGQQFSGTTASDHRLVHIPTLPPMPMHGSYVGIGSNIFVMGGFCNWKITSSVSLIDCRTHTAQTLPNMPKAVAFPVTELIDRKIYVIGGSDTLSPMKSPSRIMMVYDTDTEMWQLRARPDWEAGKKWFSSVVIGGKIYMRTYHNSFVCDPNDTSCDRDEVLHSKEWWSACVIDDVLYYYDVRENCLRAYDPKQRAWGVVKGFEGLLPVACKWSKTVSYTGGKLVLFLQKTEKTEIWCAEIAVERREGGEIWGKVEWCNVVLSGNFHIMDCVAVVL
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
F-box/kelch-repeat protein At4g38940.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_MESFL
Sequence: MKLIVGLGNYGSQYEATRHNAGWIALDQLIEKYGFTQQKNEHNSIIFFSTVNNEKVLFVKPQTYMNNSGIAIQAIMHYYKIEIKDLVILHDEKDFPVGKNQFKMNGSAAGHNGIKSVIQYLGTQNFNRYRIGIGQPEQGWKIIDWVLSKFKPEELENIILASKSISNFVNDWTKGTTFQNIMNLYN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_AGARV
Sequence: MRVIFMGTPDFSVGTLEAIIEAGHEVALVVTQPDKPKGRGKTMQYTPVKECALSHGIEVFQPVKIRETANIEYLRKFNADIIIVVAFGQILSKSILDMPRYGCINVHASLLPKYRGAAPIQWAVINGDEFTGVTTMRMDEGVDTGDMIAKSTVRLAPDETGGSLFDKLSAEGAKLCVETMKMIEDGTAEYTPQNSEEATHTSMISKELGFIDWTKPAVEIERLIRGLNPWPSAYTHLNGKTFKVWSAKVIDGSDDYEPGCIYHIGKNDMYVQTGKGALSLVEVQLQGKKRMDTGSFLRGCHVEEGSFFTL
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CUP7_DROME
Sequence: MYKYLFCLALIGCACADNINKDAQIRSFQNDATDAEGNYQYAYETSNGIQIQEAGNANGARGAVAYVSPEGEHISLTYTADEEGYHPVGDHLPTPPPVPAYVLRALEYIRTHPPAPAQKEQQ
What is the function of this protein?
Component of the cuticle of the pupa of fruit fly.
What are the official names of this protein?
Pupal cuticle protein Edg-78E.
Protein: RL33_PROMA
Sequence: MAKKGTRIVVTLECTECRSAPASEKRSPGVSRYTTEKNRRNTSDRLELKKFCPQLNKMTIHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.