PharMolix/UniProtQA huggingface dataset:
Protein: MTRA_METBF
Sequence: MADKKEPAPGWPILKGEYEVGDVKNCVLVITCGSHLPGQPILDAGAAVTGSCKTENLGIEKVVAHIISNPNIRYLLVTGSEVKGHITGQSVMSLHANGVKDNRISGALGAIPYVENLNEDAIARFQEQVDVVNLLDTEDMGAITSKVKELASKDPGAFDAEPMIVEISEEGEEEEEGGAVRPVSGEIAVIRSRLKAIEARMMDIGNLNKFHSGVHAGKIEGAMIGLTVTISLLGLLLLGR
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit A, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A.
What is the protein family that this protein belongs to?
Belongs to the MtrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YIB2_YEAST
Sequence: MCLGKLYFEQLILVRCIKGRQSGNITTGESRCVSWNVYCTTSMIGLFSWRKMLLFQHFSYTQRENRQIGGKTWSLISSLFHLNETLASALHHPYETLALYEAYFALREKKFLL
What are the official names of this protein?
Uncharacterized protein YIL012W.
Protein: DAPEL_STRPI
Sequence: MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQIRTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTIALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLKVGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVNPIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFDMEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDGVMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: CALC2_ONCNE
Sequence: CSNLSTCVLGKLSQDLHKLQTFPRTNTGAGVP
What is the function of this protein?
Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
What are the official names of this protein?
Calcitonin-2.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECF_STAAR
Sequence: MKLNTLQLENYRNYDEVTLKCHPDVNILIGENAQGKTNLLESIYTLALAKSHRTSNDKELIRFNADYAKIEGELSYRHGTMPLTMFITKKGKQVKVNHLEQSRLTQYIGHLNVVLFAPEDLNIVKGSPQIRRRFIDMELGQISAVYLNDLAQYQRILKQKNNYLKQLQLGQKKDLTMLEVLNQQFAEYAMKVTDKRAHFIQELESLAKPIHAGITNDKEALSLNYLPSLKFDYAQNEAARLEEIMSILSDNMQREKERGISLFGPHRDDISFDVNGMDAQTYGSQGQQRTTALSIKLAEIELMNIEVGEYPILLLDDVLSELDDSRQTHLLSTIQHKVQTFVTTTSVDGIDHEIMNNAKLYRINQGEIIK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAF2_HOLDI
Sequence: MKRLFVITAFFLFGAEAQNSVIDAAVVNIFGNASEYIPPGYEIVTKAPLGALTALPRCGTGADQGKKVCIVYHRCDGVTNTVTPEEVINTTGEGIFDIRENANECESYLDVCCGLPEGGVLPTPSPTPPVVPVLKPSFCGIRNERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQQSQIFDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLDQTFVCAGGEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIGCGDENVPGVYANVAHFRNWIDQEMQAKGLSTTPYVE
What is the function of this protein?
Binds and activates processed prophenoloxidases PPO1 and PPO2 and thus is involved in the activation of the prophenoloxidase cascade probably following the recognition of pathogen-derived products.
What are the official names of this protein?
Phenoloxidase-activating factor 2, 45 KDa PPAF, Hd-45, Prophenoloxidase-activating factor II, Serine protease-like PPAF-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the hemolymph.
Protein: DNAK_NEIMF
Sequence: MAKVIGIDLGTTNSCLAISENGQTKVIENAEGARTTPSVIAYLDGGEILVGAPAKRQAVTNAKNTIYAAKRLIGHKFEDKEVQRDIESMPFEIIKANNGDAWVKAQGKELSPPQISAEVLRKMKEAAEAYLGEKVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAFGMDKGDNKDRKVAVYDLGGGTFDISIIEIANLDGDKQFEVLATNGDTFLGGEDFDQRLIDHIIAEFKKEQGIDLKQDVMALQRLKEAAEKAKIELSSGQQTEINLPYITMDATGPKHLAMKITRAKFESLVEDLIARSIEPCRTALKDAGLSTSDIDDVILVGGQSRMPKVQEAVRDFFGKEPRKDVNPDEAVAVGAAIQGEVLSGGRSDVLLLDVTPLSLGIETMGGVMTKLIQKNTTIPTKASQVFSTAEDNQSAVTIHVLQGERERASANKSLGQFNLGDIAPAPRGMPQIEVTFDIDANGILHVSAKDKGTGKAANITIQGSSGLSEEEIERMVKDAEANAEEDKKLTELVASRNQAEALIHSVKKSLADYGDKLDAAEKEKIEAALKEAEEAVKGDDKAAIDAKTEALGAASQKLGEMVYAQAQAEAQAGESEQANASAKKDDDVVDADFEEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: AROA_SALTI
Sequence: MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGGPLRASGTLELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGGDIEVDGSVSSQFLTALLMTAPLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARMSTPA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OVGP1_PIG
Sequence: MGKLLLWVGLVLVLKHHNGAAHKLVCYFANWAFSRPGPASILPRDLDPFLCTHLVFAFASMNDSQIVAKDARDESIFYPEFNQLKERNEKLKTLLSIGGWNFGTSRFTTMLSTFTNREKFIRSAIGLLRTHGFDGLDLFFLYPGLRGSPRRDRWNFLFLLEELLLAFRREAQLTMRPRLLLSAAVSADPHVIQKAYDVRLLGRLLDFINVLSYDLHGSWEKVTGHNSPLFSLSDDPKSSAYTMNYWRKLGAPPEKLLMGFPTYGRTFRLLKASKNELGAEAVGPASPGKYTKQAGFLAYYEVCSFVQRAKKRWIDHQYVPYAYRGKEWVGYDDDISFSYKAFFIKKEHFGGAMVWTLDLDDVRGTFCGTGPFPLVYMLNDLLLKAEVSSTLSPGFGLSTTVNSSRTCPESLAVTKDLTTDLGILPLGGEAVATETHGRSDNMTVTPGGGLVAPTRPTLSFGKLTVAPEGKTESPGEKAMTPVGHPSVTPGDMSVPPVPIQTGDRITPPRRQAVAPEKMTLPSGKRSD
What is the function of this protein?
Binds to oocyte zona pellucida in vivo.  May play a role in the fertilization process and/or early embryonic development.
What are the official names of this protein?
Oviduct-specific glycoprotein, Estrogen-dependent oviduct protein, Oviductal glycoprotein, Oviductin, POSP-E3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
Protein: SST_EMENI
Sequence: MSPLNGVARSFPRPFQAVTRRPFRVVQPAIACPSNSRSFNHSRSLRSTGSQSPAPSPRDSSNPALSFPCLDAQEAKSALLSARSLGSGPEPSYTAGHHERFHSDEPLLLDWGGLLPEFDIAYETWGQLNEKKDNVILLHTGLSASSHAHSTEANPKPGWWEKFIGPGKTLDTDKYFVICTNVLGGCYGSTGPSTVDPSDGKKYATRFPILTIEDMVRAQFRLLDHLGVRKLYASVGSSMGGMQSLAAGVLFPERVGKIVSISGCARSHPYSIAMRHTQRQVLMMDPNWARGFYYDSIPPHSGMKLAREIATVTYRSGPEWEKRFGRKRADPSKQPALCPDFLIETYLDHAGEKFCLEYDANSLLYISKAMDLFDLGLTQQLATKKQRAEAQAKISSGTNTVNDASCSLTLPEQPYQEQPSASTSAEQSASASETGSAPNDLVAGLAPLKDHQVLVIGVASDILFPAWQQREIAETLIQAGNKTVEHIELGNDVSLFGHDTFLLDVKNVGGAVRKFLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.  Has also weak serine acetyl transferase activity and homoserine succinyl transferase activity.
What are the official names of this protein?
Serine O-succinyltransferase, SST.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL30_LISMO
Sequence: MAKLEITLKRSLIGRPQPQRKTVQALGLGKTNSVVVKEDNPAIRGMITKVSHLVDVKEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SYM_XANOP
Sequence: MTRTALVTTALPYANGPLHLGHLVGYIQADIWVRARRLRGDKTWFVCADDTHGTPIMLAAEKAGVTPEAFIASIQASHERDFAAFGVTFDHYDSTNSPVNRELTEAFYTKLEAAGHISRRSVAQFYDPAKGMFLPDRYIKGICPNCGSADQYGDNCEVCGATYAPTELKEPRSVISGATPELRDSEHFFFEVGQFDGFLHEWLAGDVALPGVKAKLKEWLDAEGGLRAWDISRDAPYFGFQMPGQPGKYFYVWLDAPIGYLCSFKTLCAQMGEDFAAHLVDGTQTELHHFIGKDIVNFHGLFWPAVLHGTGHRAPTRLHVNGYLTVDGAKMSKSRGTFVMARTFLDVGLEPEALRYYFAAKSSGGVDDLDLNLGDFIARVNADLVGKFVNLASRCAGFIGKRFDGKLAEALPDAAQYDRFVAALAPIREAYERNDAASAIRQTMALADEANKYIDDTKPWVIAKQDSADAQLQSVCTQGLNLFRVLVAALKPILPRTCAEAEAFLSAPMTSWEDVIRPLTSHTIQPYTALFTRIDPKLIDAMTDASKDTLAAPAAPATTSKAAPAKPDTKPAAAANPQSPISNPSFIGMDDFAKLDLRIGKVLVCECVEGSDKLLRFELDAGELGKRQIFSGIRASYGEPEALVGRSVVFIANLAPRKMRFGISDGMILSAGFDGGALALLDADSGAQPGMPVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_BORBU
Sequence: MGIEPNILENKKRHIEICLNKNDVKGGCNFLKFIKLKHNALSDFNFSEINIKEEIFGYNISMPVFISSMTGGSKEGNDFNKSLVRIANYLKIPIGLGSFKLLFKYPEYIRDFTLKRYAHNIPLFANVGAVQIVEFGISKIAEMIKRLEVDAIIVHLNAGQELMKVDGDRNFKGIRESIAKLSDFLSVPLIVKETGFGISPKDVKELFSLGASYVDLAGSGGTNWILVEGMKSNNLNIASCFSDWGIPSVFTLLSIDDSLKANIFASGGYETGMDIAKGIALGARLIGVAAVVLRAFYDSGEDAVFGLFSDYEHILKMSMFLSGSKSLLEFRNNKYFLSSYLLDELGVFKQFYGT
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHP2_ORYSJ
Sequence: MEYSNLRRQIIFMKKNLFDQGYLDEQFNQLEELQDESSPNFVEEVAALFFKDSSRLLTNIEQAIDKYPQDFYRLDSLVQQLKGSGSSIGALRMKNECSVFKVNCNDRNLEGCRRSLQKMKREHATLKQKLESYFQLLRQVGPRDYAVSSRK
What is the function of this protein?
Functions as two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs).  Plays an important role in propagating cytokinin signal transduction.
What are the official names of this protein?
Pseudo histidine-containing phosphotransfer protein 2, OsHpt4.
Protein: MA659_ARATH
Sequence: MSKSQIESTWSSLLQELEIIWKEVGETETEREKILIEIEEECREVYNRKIEKVKEEKIRIKQEIADSEARVIDICSVMEEPPILGRHHQSDQQSGNGRSLKDELVKILQKLEEMEKRKSERKIQFIQVIDDIRCVREEINGESDDETCSSDFSADESDLSLRKLEELHRELYTLQEQKRNRVKQIQDNIRTLESLCSVLGLNFRETVTKIHPSLVDTEGSRSISNETLDKLASSVQQWHETKIQRMQELQDLVTTMLEFWNLMDTPAEEQQKFMDVSCNIAATVSEITKPNSLSIDLLEEVKAELCRLEELKWSKMKELVLKKRSELEEICRRTHIVLEEEDIAVENVIKAIESGDVNPENILEQIEYRAGKVKEEALSRKEILEKADKWLNACEEENWLEEYNQDENRYNAGKGSHLILKRAEKARALVNKLPAMVEALASKITIWESEKEYEFLFDGNRLLSMLEEYTELREEKEQERRRKRDLKKHQGQVTSEQDKGSVTKPQSAKKGLKVSTNKRFVSSPHTPQTDSPHSAKSNQSFSTPLSRHG
What are the official names of this protein?
65-kDa microtubule-associated protein 9, AtMAP65-9.
What is the protein family that this protein belongs to?
Belongs to the MAP65/ASE1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole.
Protein: CP17A_SHEEP
Sequence: MWVLLAVFLLTLAYLFWPKTKHSGAKYPRSLPSLPLVGSLPFLPRRGQQHENFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGRPKVATLDILSDNQKGIAFADHGAHWQLHRKLVLNAFALFKDGNLKLEKIINQEANVLCDFLATQHGQSIDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQNVNDGILEVLGKEVLLDIFPALKIFPSKAMEKMKGCVETRNELLSEILEKCQENFTSDSITNLLHILMQAKVNADNNNTGPEQDSKLLSNRHMLATIADIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDSIDQNIGFNRTPTISDRNRLVLLEATIREVLRIRPVAPMLIPHKAIIDSSIGDLTIDKGTDVVVNLWALHHNEKEWQQPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDDGKLPSLEGNPSLVLQIKPFKVKIEVRQAWKEAQAEGSTS
What is the function of this protein?
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.  Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways.  A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage.  The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol.  Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione.  Has 16-alpha hydroxylase activity.  Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA.  Also 16-alpha hydroxylates androgens, relevant for estriol synthesis.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Microsome membrane.
Protein: PHOC_MORMO
Sequence: MKKNIIAGCLFSLFSLSALAAIPAGNDATTKPDLYYLKNEQAIDSLKLLPPPPEVGSIQFLNDQAMYEKGRMLRNTERGKQAQADADLAAGGVATAFSGAFGYPITEKDSPELYKLLTNMIEDAGDLATRSAKEHYMRIRPFAFYGTETCNTKDQKKLSTNGSYPSGHTSIGWATALVLAEVNPANQDAILERGYQLGQSRVICGYHWQSDVDAARIVGSAAVATLHSDPAFQAQLAKAKQEFAQKSQK
What are the official names of this protein?
Major phosphate-irrepressible acid phosphatase, HPAP.
What is the protein family that this protein belongs to?
Belongs to the class A bacterial acid phosphatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PG055_VACCW
Sequence: MGFCIPSRSKMLKRGSRKSSSILARRPTPKKMNIVTDLENRLKKNSYIENTNQGNILMDSIFVSTMPVETLFGSYITDDSDDYELKDLLNVTYNIKPVIVPDIKLDAVLDRDGNFRPADCFLVKLKHRDGFTKGALYLGHSAGFTATICLKNEGVSGLYIPGTSVIRSNICQGDTIVSRSSRGVQFLPQIGGEAIFLIVSLCPTKKLVETGFVIPEISSNDNAKIAARILSEKRKDTIAHINTLIQYRQQLELAYYNSCMLTEFLHYCNSYAGTIKESLLKETIQKDINITHTNITTLLNETAKVIKLVKSLVDKEDTDIVNNFITKEIKNRDKIVNCLSLSNLDFRL
What is the function of this protein?
Stimulates increases in peripheral microtubule dynamics and may increase the motility of the infected cells, contributing to cell-to-cell spread of the virus.  Seems to inhibit the signaling via the GTPase RHOA and DIAPH1/mDia.
What are the official names of this protein?
Protein OPG055, Protein F11.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG055 family.
Protein: MDH_XYLF2
Sequence: MKALVRVAVTGAAGQIGYSLLFRIAAGEMFGKDRPVILQMLELPDEKAQAALKGVMMELEDCAFPLLAGMVVTDNPDIAFKDADAALLVGSRPRGPGMERKDLLMENAKIFTAQGAALNKVARRDVKVLVVGNPANTNAYIAMKSAPDLNPKHFTAMLRLDHNRALSQLSTKLGKPVANIEKLIVWGNHSPTMYPDYRFATADGTPIIEAINDQAWNANSFIPTVSKRGAAIIEARGLSSAASAANAAIDHMRDWLLGSNGKWITMGVPSDGSYGIPEGMIFGFPVTTTNGEYSIVKDLPIDTFSKTYIDKTLAELEEERASIAHLLR
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: UVRC_NOSP7
Sequence: MTISTQILPLVKEPERLENRLAEIPPEPGVYFMRDNSDRIIYIGKSRKLRSRVRSYFRDGYNKTERIATMVKLVTEIEFIVTDTEAEALALEANLIKQHQPYFNVLLKDDKKYPYLCITWSEDYPRIFITRKRQLGKEKDKFYGPYTDAGLLREIVRICKRIFPQRQRPQPLFKDRPCLNYDLGRCPGVCQKLTSPEEYRKIVQKIAMVFQGRTQELIDILTQQMNAAAENLNFESAARIRDQISGLKSLTADQKVSLPDDTVSRDAIALAANEEHACIQLFQIRAGQLVGRLAFVADAHAELGAILQRALEEHYQTADSVEIPLEILVQHDLPDSDILADVLTQRKGKKVTILTPLRQTKAELIEMVERNAQYELQRMQKFGDRNHQAMQDLAAILDLPDVPHRIEGYDISHIQGSNAVASQVVFIDGLPAKQHYRHYKIKNPTVTAGHSDDFASLAEVIQRRFRKYAEDPQLSRLGNPDWPDLIMIDGGKGQLSSVTAVLQEMNLLEDLRVVSLAKQREEIFLPGESKPSSTDAEQPGVQLLRRLRDEAHRFAVSFHRQQRSDKLKRSRLDEIPGLGHHRQKQLLGHFRSVDYIRQATTPQLAEVPGIGPRLAQEIYDYFHPA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCE2_RAT
Sequence: MASPGSGFWSFGSEDGSGDPENPGTARAWCQVAQKFTGGIGNKLCALLYGDSEKPAESGGSVTSRAATRKVACTCDQKPCSCPKGDVNYALLHATDLLPACEGERPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILTHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMLIARYKMFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEVKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLNGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHIDKCLELAEYLYNIIKNREGYEMVFDGKPQHTNVCFWFVPPSLRVLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL
What is the function of this protein?
Catalyzes the production of GABA.
What are the official names of this protein?
Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, GAD-65, Glutamate decarboxylase 65 kDa isoform.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasmic vesicle. Presynaptic cell membrane; Lipid-anchor. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
Protein: ACP_HAEIN
Sequence: MSIEERVKKIIVEQLGVKEEDVKPEASFVEDLGADSLDTVELVMALEEEFDIEIPDEEAEKITTVQSAIDYVQNNQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALL5_HUMAN
Sequence: MAGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLTAAKKARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLAQE
What is the function of this protein?
Binds calcium.  May be involved in terminal differentiation of keratinocytes.
What are the official names of this protein?
Calmodulin-like protein 5, Calmodulin-like skin protein.
Protein: RIMP_SHISS
Sequence: MGLSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEZA_STRPN
Sequence: MIGKNIKSLRKTHDLTQLEFARIVGISRNSLSRYENGTSSVSTELIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGISIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Upon expression in E. coli neutralizes the toxic effect of cognate toxin PezT.  Represses transcription of its own operon, PezT acts as a corepressor, considerably increasing repression.
What are the official names of this protein?
Antitoxin PezA.
Protein: PTH_PHOLL
Sequence: MSNIKLIVGLANPGAEYAQTRHNAGAWYVDLLARSHNQSLKEESKFFGYTARINICGHDVRLLVPTTFMNLSGKSVVALASFYRIQPDEILVAHDELDLPPGVAKMKLGGSHGGHNGLKDIQNKFGNNPNFYRLRIGIGHPGDKNKVVGFVLGKPPASEQQLIDDAIDEARRCTDILMKQDMDKAINRLHSFKASV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USPB_VIBCM
Sequence: MISGDTILFALMLVTAINVARYVTALRSLIYIMREAHPLLYQQVDGRGFFTTHGNVTKQVRLYHYLKSREYHHHHDPVFTGKCDRVRELFILSGSLLVLTTVVAFML
What are the official names of this protein?
Universal stress protein B homolog.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INO1_POPEU
Sequence: MFIEKFKVESPNVKYTEDEIHSVYNYETTELVHENKNGSYQWTVKPKTVQYEFKTDIHVPKLGVMLVGWGGNNGSTLTGGVIANREGISWATKDKVQQANYFGSLTQASSIRVGSFNGEEIYAPFKSLLPMVNPDDIVFGGWDISDMNLADAMARAKVFDFDLQKQLRPYMESMVPLPGIYDPDFIAANQDSRANNVIKGTKKEQVQQIIKDIREFKEKNKVDKVVVLWTANTERYSNIVVGLNDTMENLLAAVEKDESEISPSTLYALACIYENIPFINGSPQNTFVPGLVDLAIKRNSLIGGDDFKSGQTKMKSVLVDFLVGAGIKPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVSSNGILYEPGEHPDHVVVIKYVPYVGDSKRAMDEYTSEIFMGGKNTIVLHNTCEDSLLAAPIILDLVLLAELSTRIQLKGEAEGKFHSFHPVATILSYLTKAPLVPPGTPVVNALSKQRAMLENILRACVGLAPENNMILEYK
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner (PubMed:29579299).  May play a role in oxidative stress resistance and influences ascorbate levels (PubMed:29579299).
What are the official names of this protein?
Inositol-3-phosphate synthase 1, MIP synthase 1, Myo-inositol 1-phosphate synthase 1, PeMIPS 1.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
Protein: PNP_STAA9
Sequence: MSQEKKVFKTEWAGRSLTIETGQLAKQANGAVLVRYGDTVVLSTATASKEPRDGDFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDDATLTARLIDRPIRPLFPKGYKHDVQIMNMVLSADPDCSPQMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGKYIINPTVEEKEVSRLDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQRLVDFQQQIVDHIQPVKQEFIPAERDEALVERVKSLTEEKGLKETVLTFDKQQRDENLDNLKEEIVNEFIDEEDPENELLIKEVYAILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSEVGILPRTHGSGLFTRGQTQALSVLTLGALGDYQLIDGLGPEEEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERALKYIIPDTADFPYTIRIVSEVLESNGSSSQASICGSTLALMDAGVPIKAPVAGIAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGITAIQMDIKIDGLTREIIEEALEQARRGRLEIMNHMLQTIDQPRTELSAYAPKVVTMTIKPDKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAVDQAMINRAREIIEEITREAEVGQTYQATVKRIEKYGAFVGLFPGKDALLHISQISKNRIEKVEDVLKIGDTIEVKITEIDKQGRVNASHRALEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.