PharMolix/UniProtQA huggingface dataset:
Protein: CYB6_PROM5
Sequence: MSNSSSVYDWFQERLEIQDITDDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVTQAYNSVSYLMTDVSFGWLIRSVHRWSASMMVLMLILHVFRVYLTGGFKRPRELTWVTGVVMAVITVAFGVTGYSLPWDQVGYWAVKIVSGVPAAIPIIGDFMVELLRGGESVGQSTLTRFYSLHTFVLPWSLAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SI1L1_MOUSE
Sequence: MTSLKRSQTERPVTADRASVVSTDGAPKVHTDDFYMRRFRSQNGSLGSSVMAAVGPPRSEGPHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESLSSKGSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTGPAESMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKSGPSLHREYGSTSSIDKQGTSGDSFFDLLKGYKDDRSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLGMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESTSFESALSSHCTNAGVAVLEVPKESLMLHLDRVKRYTVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEDMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRAHNPCTESVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEFDCLLGISSEFIVLIEQETKSVAFNCSCRDVIGWTSSDTSLKIFYERGECVSVESFISGEDIKEIVRRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYQMNEGISYEFKFPFRNNNKWQRNASKGAHSPQVPSQLQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSETGSGGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDISGSGKSTPSWQRSEDSLADQMEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESDLNSYNYLQGTSADSGIDTASYGPSHGSTASLGASTSSPRSGPGKEKVAPLWHSSSEVLSLADRTLETEGHGMDRKAESSLSLDIHSKSQGGSSPLSRENSTFSINDAASHTSTMSSRHSASPVVFSSARSSPKEELHPTASSQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLQASPKPTSKSTIEEDLKKLIDLESPTPESQKNFKFHALSSPQSPFPTTPTSRRALHRTLSDESIYSSQREHFFTSRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPIPDPGLMPLPDAASDLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEEQALVQMKSYSSKDPSPTLASKVDQLEGMLKMLREDLKKEKEDKAQLQAEVEHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS
What is the function of this protein?
Stimulates the GTPase activity of RAP2A.  Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin.  Contributes to the regulation of dendritic spine morphogenesis (By similarity).
What are the official names of this protein?
Signal-induced proliferation-associated 1-like protein 1, SIPA1-like protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Postsynaptic density. Synapse, synaptosome. Note=Associated with the actin cytoskeleton. Detected at synapses and dendritic spines of cultured hippocampal neurons (By similarity).
Protein: RP8HA_ARATH
Sequence: MAEGFVSFGLEKLWDLLSRESERLQGIDEQLDGLKRQLRSLQSLLKDADAKKHGSDRVRNFLEDVKDLVFDAEDIIESYVLNKLRGEGKGVKKHVRRLARFLTDRHKVASDIEGITKRISEVIGEMQSFGIQQIIDGGRSLSLQERQRVQREIRQTYPDSSESDLVGVEQSVTELVCHLVENDVHQVVSIAGMGGIGKTTLARQVFHHDLVRRHFDGFAWVCVSQQFTQKHVWQRILQELQPHDGEILQMDEYTIQGKLFQLLETGRYLVVLDDVWKKEDWDRIKAVFPRKRGWKMLLTSRNEGVGIHADPTCLTFRASILNPEESWKLCERIVFPRRDETEVRLDEEMEAMGKEMVTHCGGLPLAVKALGGLLANKHTVPEWKRVSDNIGSQIVGGSCLDDNSLNSVYRILSLSYEDLPTHLKHCFLHLAHYPEDSKIYTQDLFNYWAAEGIYDGSTIQDSGEYYLEELVRRNLVIADNRYLISEFKIKNCQMHDMMREVCLSKAKEENFLQIIKDPTCTSTINAQSPSRSRRLSIHSGKAFHILGHKRNAKVRSLIVSRFEEDFWIRSASVFHNLTLLRVLDLSWVKFEGGKLPCSIGGLIHLRYLRLYGAVVSHLPSTMRNLKLLLYLNLSVHNEDLIHVPNVLKEMIELRYLSIPVKMDDKTKLELGDLVNLEYLYGFSTQHTSVTDLLRMTKLRNLTVSLSERYNFKTLSSSLRELRNLETLYVLFSRKTYMVDHMGEFVLDHFIHLKELGLVVRMSKIPDQHQFPPHLVHIFLFYCGMEEDPMPILEKLHHLKSVQLRYKAFVGRRMVCSKDGFTQLCALDISKQSELEDWIVEEGSMPCLRTLTIHDCEKLKELPDGLKYITSLKELKIEGMKREWKEKLVPGGEDYYKVQHIPDVQFINCDQ
What is the function of this protein?
Disease resistance protein.  Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein.  That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.  In contrast to RPP8, it does not specifically recognize the Emco5 avirulence protein from Hyaloperonospora parasitica.
What are the official names of this protein?
Disease resistance protein RPH8A, RPP8 homolog A.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family. RPP8/HRT subfamily.
Protein: SBCC_STAAC
Sequence: MKPLHLKLNNFGPFLKEEIDFSKIDNNELFLISGKTGSGKTMIFDAMTYALFGKASTEQREENDLRSHFADGKQPMSVTFEFQLNHRIYKVHRQGPYIKEGNTTKTNAKFDVFEMVDGKYEIRESKVISGTQFIIELLGVNADQFRQLFILPQGEFKRFLISNSREKQGILRTLFDSEKFEAIREILKEEVKKEKAQIENRYQQIDLLWQEIESFDDDNIKGLLEVATQQIDKLIENIPLLQARSKEILASVNESKETAIKEFEIIEKKTLENNILKDNINQLNKNKIDFVQLKEQQPEIEGIEAKLKLLQDITNLLNYIENREKIETKIANSKKDISKTNNKILNLDCDKRNIDKEKKMLEENGDLIESKISFIDKTRVLFNDINKYQQSYLNIERLRTEGEQLGDELNDLIKGLETVEDSIGNNQSDYEKIIELNNTITNINNEINIIKENEKAKAELDKLLGSKQELENQINEETSILKNLEIKLDRYDKTKLDLNDKESFISEIKSAVNIGDQCPICGNEIQDLGHHIDFDSIAKRQNEIKEIEANIHAIKSNIAVHNSEIKFVNEKISNINIKTQSDFSLEVLNKRLLENENALNNQRDLNKFIEQMKEEKDNLTLQIHNKQLRLNKNESELKLCRDLITEFETLSKYNNITNFEVDYKKYVQDVNQHQELSKEIEDKLMQLSQRKLIEQNNLNHYENQLETYNNDLELNEQSIEMEMSRLNLTDDNDIDEIIAWRGEQEELEQKRDTYKKRYHEFEMEIARLESLTKDKELLDSDKLKDEYELKKGKMNTLIDEYSAVHYQCQNNINKTQSIVSHINYLNQELKDQQEIFQLAEIVSGKNNKNLTLENFVLIYYLDQIIAQANLRLATMSDNRYQLIRREAVSHGLSGLEIDVFDLHSNKSRHISSLSGGETFQSSLALALGLSEIVQQQSGGISLESIFIDEGFGTLDQETLETALDTLLNLKSTGRMVGIISHVSELKNRIPLVLEVKSDQYQSSTRFKRN
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit C.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SbcC subfamily.
Protein: LEXA_ECO81
Sequence: MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: TXLNG_MOUSE
Sequence: MATRLEEVTRGRGGGTEEASEGGRGGRRRSPPQKFEIGTMEEARICGLGVKADMVCNSQANDILQHQDPSCGGTTKKHSLEGDEGSDFITKNRNLVSSVFCTQEKREEIPGREARTGPPDGQQDSECSRNKEKTLGKEVLLLMQALNTLSTPEEKLAALCKKYADLLEESRNVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLNEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKHKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKAFQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAADGDLVSPATQPCAVLDSFKETSRRTLGMHLEARAKSVCEKSAAQKPSSSGSPAQGIESVD
What is the function of this protein?
May be involved in intracellular vesicle traffic (By similarity).  Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA.  May be involved in regulating bone mass density through an ATF4-dependent pathway.  May be involved in cell cycle progression.
What are the official names of this protein?
Gamma-taxilin, Factor inhibiting ATF4-mediated transcription, FIAT, Lipopolysaccharide-responsive gene protein.
What is the protein family that this protein belongs to?
Belongs to the taxilin family.
What are the subcellular locations of this protein?
Nucleus membrane. Cytoplasm, cytosol.
Protein: RRF_STRAW
Sequence: MIEETLLEAEEKMEKAVVVAKEDFAAIRTGRAHPAMFNKIVADYYGALTPINQLASFSVPEPRMAVVTPFDKSALRNIEQAIRDSDLGVNPSNDGNIIRVVFPELTEERRKDYIKVAKTKGEDAKVSIRSVRRKAKDAIDKLIKDGEVGEDEGRRAEKELDDTTAKYVAQVDELLKHKEAELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S6A11_RAT
Sequence: MTAEQALPLGNGKAAEEARGSEALGGGGGGAAGTREARDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTEKCVEFQKLNFSNYSHVSLQNATSPVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIVSYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKYNNVYTYPAWGYGIGWLMALSSMLCIPLWIFIKLWKTEGTLPEKLQKLTVPSADLKMRGKLGASPRMVTVNDCEAKVKGDGTISAITEKETHF
What is the function of this protein?
Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:1400419, PubMed:1497897).  Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity).
What are the official names of this protein?
Sodium- and chloride-dependent GABA transporter 3, GAT-3, Solute carrier family 6 member 11.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A11 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1706_HAEIN
Sequence: MTKRTSFNPLVIGVTLFFILLLMAMIFIAPEQTQALLNQAKSGIFANFSWFYVLTFSVFLGFLLILSVSSLGNIKLGQDEEEPEFSFLSWLAMLFAAGMGVGLMFFGVAEPLTHYLSDITAGSAEHKQQEALLHTLFHWGIHAWAVYGTIALALAYFGFRYKLPLALRSCFYPLLKDRINGKIGDAIDVMALLATLFGIITTLGFGSSQLGAGLEQIGWISQNSFALQVGVIVVVMCLAVFSAISGVGKGVKILSEINLTLAFCLLLFVLISGPTLYLLSAFSDNIGNYFSNLVQLSFKTYAYEQEHTSWFSGWTVLYWAWWCSWAPFVGLFIARISKGRTIREFIFGVLVIPSLFGILWFTVFGNTAVWLNDGIAAGGLGEFISSPEILLFKFLNYLPLPTITGFVSLLVILLFFITSADSGIYVLNNIASRDKSLASPAWQAIMWGTLMSVVAIVLMQSGGLANLQTMTLIVALPFALLMLVMCFSLWKGLIADKKYFSTKVNPTSIFWSGDKWKSHLEQMMNQTQEKDILRFLKNTALPAMRELRQELTGKYNLSVEINTLFEQEEPALELVIHKESMRDFMYGIKSVGREVSEQLINDENLPHIQHSATYEPYTYFFDGRVGYDVQYMDQDELIADMLKQYERYLSLLDDVGQELMAHEQTELAE
What are the official names of this protein?
Uncharacterized transporter HI_1706.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXB_VIBCH
Sequence: MKILIDENMPYAQALFSQLGEVILKPGRTLTADDLIDVDALMIRSVTKVNDALLAKANRLKFVGTATAGMDHVDQALLRERGIFFTAAPGCNKVGVAEYVFSVLMVLAQQQGFSVFDKTVGIIGAGQVGSYLAKCLSGIGMKVLLNDPPKQAQGDEREFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAARGPVVDNAALKARLQQGDGFTAVLDVFEFEPQVDMELLPLLAFATPHIAGYGLEGKARGTTMIFNSYCEFLGSAHCANPASLLPKAPVPKVYLERAWDEETLRTLTQIIYDVRKDDAQFRREIHQPGAFDLMRKHYWDRREYSAVTLAGGADCHLAPLAKLGFQVEVCDEPTI
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OVCA2_DANRE
Sequence: MSAVPLRILCIHGYRQNGNSFREKTGALRKLLKKQVELVFISAPHQVPAIQEENCGTNQQSQTVSVGDEDQRGWWFSDVQARSFNAKQDCESSLGLEESIEAVKAALKDLGPFSGILGFSQGAALVAMLCALQEQKLEPDFNFRFAILVAGFRSACLEHQRFYEGPVITIPSLHVFGQDDRVIPEEMSRDLLPAFDGAQVLLHPGGHFVPAASSHRQTYQDFLKRFQ
What are the official names of this protein?
Esterase OVCA2, Ovarian cancer-associated gene 2 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: RUXX_THEAC
Sequence: MPKTPANVKPMDVLKSALSRNVLIDVKGNREYSGILEGYDVYMNIVLQNASEIINGENKGVYDRVLVRGDNVIFVSPSKGDGS
What are the official names of this protein?
Putative snRNP Sm-like protein.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
Protein: NUC1_NEUCR
Sequence: MNSSSWSAPDHSHHPALHTAADDDFHQYLDINDMGDLSDALDFDFRDFGADHHTAPHAGRHAADHLLHPSGGEHLDTPMTGTDMSMILSPVDHAMLRHGVQQQQHHQQQQHQQHQMPTITTTAPYQNAPTALIQPSTPSEAIVNTIDAQIQFLQQQKLHAQHQQLQEQQAAFFASQQNHIVPPTPQSLELTAGSSQNYYAQSTLSDQHHSGPQKQQQPQQAIDYRYTRIKDQHDMSFTPLVSPAVTPLETHFPIDTPFAVPGAYFSPLTSPALHAQNDALGIIDQRLGMMSGSSPREMELEPPAMSQASVSPGDLARKTRKNAVKARAKSGSGIKQSPISKPIRRKTATTPMLNPQALNQLVENAAPSQERQQPLTPLIPTSSSSTAGVTDSENGSISPENLNDVVLPVEMPPPPLPKPRSAKPSPFLAPQASGSAVPINLQPGRPGIASPATPASLMKLSSPSNRNPSVVGTGSHDPMDPDHIENFELPDSINFSSAPKPAPIITTLGTPALDPLQKAAAPLQTPGLPPPPSPAVAKPLALPSAALSSPQLKPDSAHSLKRTPQLAPMGRSSKKRASVTSIQMSPALRPKISPSIKPLLPGGSAGAEDAASILLATKSNYQRILEGNTVPGVSYPSELSTNLTSKRTSHKIAEQGRRNRINSALQEIATLLPKAPAKEGGDGDGDGHSSSGGGGGSGGADREDKREKDKDKAGGGIPNSKASTVEMAIEYIKQLQKEVADANKRAEEAERKLVEMKMQGGAATGSGSSVGDAGDLGTPTTEANPVVDEDLKSGGGDAMDE
What is the function of this protein?
Factor that activates the transcription of structural genes for phosphorus acquisition.
What are the official names of this protein?
Phosphorus acquisition-controlling protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGK_STRP4
Sequence: MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEAAINVLEDGQVLLVENTRYEDVDGXKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAFAGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_SHEAM
Sequence: MSLRIDAVILAGGQARRMGGQDKGLVELLGKPMIEHAITRIQPQVKEILINANRNQNLYAQFADCVFGDEDSGFLGPLAGMVTAMGKTQADLLLVVPCDCPCLPTDLVARMAAALEAEAADLAVASDGEYEQPVVMLLKPSLRDSMKAFLAAGERKIDFWYAKHKVAVVSFADQPNAFVNVNTPEQVEQLSKALTQ
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_DESHD
Sequence: MGQKVNPKGLRVGIIRDWEGRWFADKNYLELLHEDLKVRKFVKTKLQQAGVPKVEIERAANRVKVSIYAAKPGIVIGRGGTEVENLRKQLEAMTGKQVAVNIVEVKKPELDAQLVAESVAQQLEKRVSFRRAMKQTVQRTMRQGGQGIKISCSGRLGGAEIARTEWYSEGKVPLHTLRADIDYGFAEANTTYGKIGVKVWIYKGEVLPAKKVAQVEGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y2135_LACPL
Sequence: MDFTVKPRRSLIVYMHSMKQVRQLKRFGLIQYQSRKEHYVVLYMDESQIPAATTKIKKLNFVRRVEPSYRPDVAMNFGERVDQGFFKPTTTGAPDDDDED
What are the official names of this protein?
UPF0298 protein lp_2135.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRBJ_BLOB1
Sequence: MSFDSIPILDLSLARNEETKPAFLRDLRHTLLEVGFLYIKNTGIPETLISDVIAQGKAFFDLPDEEKLAIEMKNKPSFLGYSRLGMEVTRFKVDWREQLDLSTPHPMPGPDDPLYYNLLAPNQWPSTPGFREVYEDYMTRMGKMSIEFTSLIAEAIGLPADAFDRFFDASQQHKLKIVKYPDLAELGVEGEAQGVGPHKDSMLTSYLLQASHHRGLQVQNHEGEWIDCPPIDGTLVVAVGQGMQALTRGVCLSTTHRVLSPARGAGARYSIPFFQGVSYDATFESMDVPESVTALRDEVQARRGAKQDDVEFTFRPGQWDHLGSATLYNRIKSHPDVGEKWDQYPEILAGIRKQHAQQGHVSEALPSG
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of the antifungal antibiotic FR901469, an inhibitor of beta-1,3-glucansynthase, exerting antifungal activity against the pathogenes Candida albicans and Aspergillus fumigatus (PubMed:27660098).  FR901469 is a cyclic depsipeptide containing 12 amino acid residues and a fatty acid chain (PubMed:27660098).  The NRPS frbI contains 12 modules responsible for the formation of the depsipeptide backbone which is denoted as Acyl-Thr-Ala-Tyr-Val-4OHPro-Thr-Thr-3OHPro-threo3OHGln-Gly-Thr-Orn-OH (C71H116N14O23) (Probable).  The PKS frbB is probably involved in the production of the hydrocarbon chain, and the acyl-CoA ligase frbC might be involved in the transport of the chain to the peptide ptoduct of frbI (Probable).  Because FR901469 contains 3 hydroxylated amino acid residues, the 3 oxygenases frbA, frbH, and frbJ might be participating in amino acid hydroxylation (Probable).  As no thioesterase domains were detected in frbI or frbB, the thioesterases frbD and frbE may instead release and cyclize the products of the NRPS and PKS, respectively (Probable).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase frbJ, FR901469 biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: GDL23_ARATH
Sequence: MWTSKTISFTLFITTTLLGSCNASAKAKTQPLFPAILIFGDSTVDTGNNNYPSQTIFRAKHVPYGIDLPNHSPNGRFSNGKIFSDIIATKLNIKQFVPPFLQPNLTDQEIVTGVCFASAGAGYDDQTSLTTQAIRVSEQPNMFKSYIARLKSIVGDKKAMKIINNALVVVSAGPNDFILNYYEVPSWRRMYPSISDYQDFVLSRLNNFVKELYSLGCRKILVGGLPPMGCLPIQMTAQFRNVLRFCLEQENRDSVLYNQKLQKLLPQTQASLTGSKILYSDVYDPMMEMLQNPSKYGFKETTRGCCGTGFLETSFMCNAYSSMCQNRSEFLFFDSIHPSEATYNYIGNVLDTKIRGWLKA
What are the official names of this protein?
GDSL esterase/lipase At1g58430, Extracellular lipase At1g58430.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPF_LISMF
Sequence: MGLSNKFKSFFFLDEEEEYYEEEVAREPEPMQKKTKKEKPNKNRFYAVEEDDAKVVSMQGAQFSSRMVLAEPRVYAEAQELADYLKEYKSVVVNLQRISHDQATRIVDFLSGTVYALGGDIQRVGNNIFLCTPDNVEVDGSISEMLDEQNFM
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: THID_MYCTO
Sequence: MNYLPLAPPGMTPPRVLSIAGSDSGGGAGIQADMRTMALLGVHACVAVTAVTVQNTLGVKDIHEVPNDVVAGQIEAVVTDIGVQAAKTGMLASSRIVATVAATWRRLELSVPLVVDPVCASMHGDPLLAPSALDSLRGQLFPLATLLTPNLDEARLLVDIEVVDAESQRAAAKALHALGPQWVLVKGGHLRSSDGSCDLLYDGVSCYQFDAQRLPTGDDHGGGDTLATAIAAALAHGFTVPDAVDFGKRWVTECLRAAYPLGRGHGPVSPLFRLS
What is the function of this protein?
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
What are the official names of this protein?
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, Hydroxymethylpyrimidine kinase, HMP kinase, Hydroxymethylpyrimidine phosphate kinase, HMP-P kinase, HMP-phosphate kinase, HMPP kinase.
What is the protein family that this protein belongs to?
Belongs to the ThiD family.
Protein: MPM1_YEAS7
Sequence: MGFYEGDDNDANTKAFNDKYIKDQKFATAPFWNLFPKLRDIDEYDNPLLPLPFNFNFRDLGDSALAMASGIPTVKQFDKCEELKGQSAWTTQGIWKCLVPSKAIPPLPQLDFLLPLEEIKSDKSHSHGLFFNDFNLFLKWRSHMNRLQKQRIKTRTTAVEPLARTPEDLMLNWDDLHLGNDAEYASADGSKKIVGRAQSISTTKDSNDAKPSTVKTEKIYFDDGTVDITTTTTSKGSSPQVKHKVVSVDEDN
What are the official names of this protein?
Mitochondrial peculiar membrane protein 1.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein.
Protein: ATPG_STAA9
Sequence: MASLKEIDTRIKSTKKMKQITKAMNMVSSSKLRRAEKNTKQFTPYMDKMQDAITAVAGASSNTNHPMLRPRKITRSGYLVITSDKGLAGAYSANVLKKLITDIEAKHQDSSEYSIVVLGQQGVDFLKNRGYDIEYSQVDVPDQPSFKSVQALANHAIDLYSEEEIDELNIYYSHYVSVLENKPTSRQVLPLSQEDSSKGHGHLSSYEFEPDKESILSVILPQYVESLIYGTILDAKASEHATRMTAMKNATDNATELIDDLSLEYNRARQAEITQQITEIVGGSAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RLMF_DECAR
Sequence: MHPRNKNAEGYDFAALAATSAALAKHIKTTQAGTASIDFANPAAVKMLNRAILMHHYGVKGWDIPAGYLCPPIPGRADYIHSVADLLATCNKKNIPSGPGVRVLDIGVGANMVYPLIGHAEYGWSFLGVDIDEAALANAQSIIGKNPELASDIELRHQPVWDNIFTGLLRSGEVFDLSICNPPFHNSPDDVHAVSQRKWNNLNKPGAKRGAAEPRLNFGGGGSELWCNGGERAFVKRMIEQSCNIPKRVMWFTSLLSQGDNLPHIEAALKKAKVVESRIIPMAQGQKQSRLVAWTFCGNGEREKWRRERWTAAPSYAVPAFAEQTAPLTAEATPPAADPV
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_RHIL3
Sequence: MVNKVVAENRKARFNYEIIDTYEAGIVLMGTEVKSLREGKANIAESYASDEGGEIWLINSYLPEYLQANRFNHEPRRRRKLLLSGREIHRLRSAINREGMTLIPLKIYFNDRGRAKMELALAKGKKLHDKRESEKERDWNRQKSRLLKAHG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.