PharMolix/UniProtQA huggingface dataset:
Protein: ECPT1_ASPRC
Sequence: MPSEVLTSYYDYPTHDQEAWWRDTGPLFGRFLKGAGYDVHTQYQYLVFFIKNILPSLGPYPARWRSTITPTGLPIEYSLNFQLNSRPLLRIGFEPLSRFSGTPQDPYNKIAAADLLNQLSKLQLHEFDTQLFNHFTNEFELSKSESESLQKQGGINGKSTVRSQTAFGFDLKGGRVAVKGYAFAGLKNRATGTPVGQLISNSIRNLEPQMHCWDSFSILNSYMEESDGWNEYSFVSWDCVDIERSRLKLYGVHNAVTWDKVKEMWTLGGRIENNATIKTGLELLQHMWSLLQINEGDRDYKGGFAADNGGKTLPIIWNYELNKGSPHPAPKFYFPVHGENDLQVSKSISEFFTHLGWQDHARQYPHLLRQIYPNQNISQTERLQAWISFAYNERTGPYLSVYYYSAERPPWGSDQVK
What is the function of this protein?
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of echinulin family alkaloid (PubMed:29072465, PubMed:33381959).  The pathway begins with the biosynthesis of the cyclic dipeptide cyclo-L-Trp-L-Ala (cyclo-TA) by the NRPS echPS via condensation of L-alanine and L-tryptophan (By similarity).  The prenyltransferase echPT1 then catalyzes the first prenylation step, a reverse prenylation reaction at C2, to yield preechinulin (PubMed:29072465, PubMed:33381959).  Preechinulin is the substrate of the cytochrome P450 monooxygenase echP450 that catalyzes the formation of the double bond between C10 and C11 to produce neoechulin A (PubMed:33381959).  The unique prenyltransferase echPT2 functions as a competitive enzyme with echP450 for preechinulin metabolization and uses preechinulin for effective regiospecific prenylations.  Preechinulin is prenylated by echPT2 at C5 or C7.  C7-prenylation leads to accumulation of tardioxopiperazine B without further modification by echPT2.  In contrast, the C5-prenylated tardioxopiperazine A can be prenylated again by echPT2, predominantly at C7 to form echinulin or less frequently at C4 to give variecolorin L.  EchPT2 accepts also neoechilunin A to produce varlecolorin G (prenylation at C5) or isoechinulin A (prenylation at C7).  EchPT2 further converts isoechinulin A into dehydroechinulin.  Moreover, a yet unidentified enzyme can also convert neoechilunin A into neoechilunin B by introducing a double bond between positions C14 and C17 and thus provides a further substrate to echPT2 for C5 and C7 prenylation (PubMed:29072465, PubMed:33381959).
What are the official names of this protein?
Echinulin prenyltransferase 1, EchPT1, Echinulin biosynthesis cluster protein echPT1.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: HGD_BORPA
Sequence: MSLQYQTGFGNACATEALPGALPAGRNSPQICPYGLYAEQLSGTAFTAPRAENRRSWLYRIRPGVQHLPFAPFAGAQRWLSDFGRQPVTPNQLRWSPLPMPDAPTDFIDGMHTWGGNGGPEEQSGVGIHLYAANRSMQGRFFYNADGEMLIVPQQGRLRLATELGLIDIEPYEIAVVPRGVRLRVELLDDVARGYMLENFGTAMRLPELGPIGSNCLANARDFQIPVAWYEDVEGDFELIAKFTGGFWRAPIAHSPLNVVAWHGTHAPYKYDLRNFNTVGSISYDHPDPSIFTVLTSPSDTPGTANMDFAIFPPRILAMENTFRPPWFHRNIASEFMGLIHGVYDAKAEGFAPGGASLHNCMSGHGPDADTFEKASHADTSQAHYIRDTMAFMFETRRVIRPTAQALASPQRQDDYYQCWQGLQKHFDPEQA
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: ACUK_NEUCR
Sequence: MPDDVGPAEAEVSGAVSESDNEYDETEVTTKDDDDEKMAERSVASEGVETNGDQKKKYDPKDPLRPRRKKARRACYACQRAHLTCGDERPCQRCIKRGLAEACQDGVRKKAKYLHDAPPEALRPVLGPNYNPAAAVSVRNGHRHPSNAGSDAGSSIGTFYSQSTQYPVFSSAATQLGSIPENLPFPQQSPVSPTFQPSSNPQLGSIGVSSVSSPMNSFPPALFDPSNPAIFNFNLEGLNFGSQYGAMEFGMLGHMSSGAAETPPRDPSMAQQGTSDVGFNPSGVFGNGLNQFEKVYDNNTGLISDFLTLDAHSNGLYSQGNLQHGLPHAYAIPAGPTSLQSPSTENNSPQPTGFGFESPTATNYTGVPGAAGNQPGSQQPRAQKPKTPALGKLGPQSVLGKRQRDPSSIYEAVKEPFQYVASFHKLISLLQNRFSGASTISIVRSLASIRPSFMSCMKTLNRADLIFMEKSFQRALFEHEEFMHQSPSPAIACRRTGEIAAVNKEFTALTGWTKDVLLGKTLNLNANMGGTNSDTLSISSKGGRGGIVGTTPRLKPLHPEQGTNADSQQQQSQQHKEQPQPVFLAELMDEASVTQFYEDYAQLAFTHSRGTVVRKCRLLKYRTQENMDAAAAAAAAASAPTASGGSGSSNGTVVNGGPDSSPAGKTEKERPTGVNVASNSILSNRVAKIDGEHGISKLERDGKLECSYTWTIKRDVFDIPMIIMINFLPCYYRSHNQLAV
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis NCU03938.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTS_CUPMC
Sequence: MSEALSVPAAEGENTVTASESPDLAATSARAEKVGKQEKPEKAEKQSPMMLQYHRIKADHPDTLLFYRMGDFYELFHDDAEKAARLLDITLTARGQSGGVPIRMAGIPFHSADQYLARLVKLGESVAICEQIGDPATSKGPVERKVVRIVTPGTLTDAALLPDKSDTFLLAVHQQTTRRGVSKTGLAWLNLASGELRLMECDAAQLSRELERIRPAEVLYTDGMDLPTLTCARTRLPEWHFDQEAGTRRLREQIGVASLEPFGCSGLGAALGAAGALLNYAATTQGQSLRHVQGVTVERESEFVGLDSATRRNLELTETLRGTESPTLFSLLDTCATTMGSRALRHWLHHPLRDPALPRARQQAIGALITQGPDGLRAVLRKLADVERITARLALLSARPRDLSSLRDTLRALPDVQAATVSSEDAPLLAQTLEEIDIPQDCLELLIRAVADEPSTVIRDGGVIARGYDSELDELRDISENCGQFLIDLETRERERTGITNLRVEYNRVHGFYIEVTNGQADKVPDDYRRRQTLKNAERYITPELKAFEDKALSAQDRALAREKQLYDGLLQALLPHIGSLRRVAGALARLDVLATLAERAKTLDWVQPERVQENVIDISQGRHPVVEGQLAAESVAFIANDCQLNEARKLLLITGPNMGGKSTFMRQTALIVLLACVGAWVPARRAVIGPVDRIFTRIGAADDLAGGRSTFMVEMTEAAAILHNATPSSLVLMDEIGRGTSTFDGLALAWAIARHLLSHNRSHTLFATHYFELTQLPVEFPQAANVHLSAVEHGDGIVFLHAVQDGPASQSYGLQVAQLAGVPQPVIRAARKHLAWLEEQSADATPTPQMDLFSAQSSPSADDEDDKSAGQSAVPPAQAATLEALADIDPDSLSPREALEALYRLKSISETARTV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: YM04_SCHPO
Sequence: MSNPESLKKQVEPPGYNELFMVEDVCNVDLEQGLDLCKPEKVNKQSQRSRQSRQSLFTNTIKPQKDKMNIKTNKIKEFLNDLFTEFSKFHNSYYPNGRISTQDKSRWVLLIIWSIITILTIDKKFKIKESYLEWIGENQSHSEIWGPIVIYVGLFILLLSAFNYCSKLIIKALPLISMVIAWVGVVIAAFSVIITATIAGVIAAFSVIITATIAGVIAAMVGILYFGHWLVYKILILAFGFKIVTSGDVCVSNTLPTHNGETALHSDATVGSDIEQIELQNMPTPVKK
What are the official names of this protein?
UPF0494 membrane protein C212.04c.
What is the protein family that this protein belongs to?
Belongs to the UPF0494 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Protein: ECCA3_MYCTU
Sequence: MAGVGEGDSGGVERDDIGMVAASPVASRVNGKVDADVVGRFATCCRALGIAVYQRKRPPDLAAARSGFAALTRVAHDQCDAWTGLAAAGDQSIGVLEAASRTATTAGVLQRQVELADNALGFLYDTGLYLRFRATGPDDFHLAYAAALASTGGPEEFAKANHVVSGITERRAGWRAARWLAVVINYRAERWSDVVKLLTPMVNDPDLDEAFSHAAKITLGTALARLGMFAPALSYLEEPDGPVAVAAVDGALAKALVLRAHVDEESASEVLQDLYAAHPENEQVEQALSDTSFGIVTTTAGRIEARTDPWDPATEPGAEDFVDPAAHERKAALLHEAELQLAEFIGLDEVKRQVSRLKSSVAMELVRKQRGLTVAQRTHHLVFAGPPGTGKTTIARVVAKIYCGLGLLKRENIREVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDKFLDTNEGLRSRFTRNIDFPSYTSHELVEIAHKMAEQRDSVFEQSALHDLEALFAKLAAESTPDTNGISRRSLDIAGNGRFVRNIVERSEEEREFRLDHSEHAGSGEFSDEELMTITADDVGRSVEPLLRGLGLSVRA
What is the function of this protein?
Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis (PubMed:19684129, PubMed:24155985).  EccA3 exhibits ATPase activity and may provide energy for the export of ESX-3 substrates (By similarity).
What are the official names of this protein?
ESX-3 secretion system protein EccA3, ESX conserved component A3, Type VII secretion system protein EccA3, T7SS protein EccA3.
What is the protein family that this protein belongs to?
Belongs to the CbxX/CfxQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_HELPH
Sequence: MKIGVFDSGVGGFSVLKSLLKAQIFDEIIYYGDSARVPYGTKDPTTIKQFGLEALDFFKPHQIKLLIVACNTASALALEEMQKHSKIPIVGVIEPSILAIKQQVKDKNAPILVLGTKATIQSNAYDNALKQQGYLNVSHLATSLFVPLIEESILEGELLETCMRYYFTPLEILPEVVILGCTHFPLIAQKIEGYFMEHFALSTPPLLIHSGDAIVGYLQQKYALKKNACAFPKVEFHASGDVVWLEKQAKEWLKL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: Y475_CHLMU
Sequence: MEISHILEDLVYDNGVLPREAIEAAIVKHNQITPYLLKILEEAIDHVSDIIDDDCYQGHLYAMYLLAQFRETRALPLIIKLFSFEQDIPHAIAGDVLTEDLSRILASVCDDVSLIQELIETPRVNPYVQAAAISSLVSLVGVKKLSRGAAIRYFGELLNYRLEKRPSFAWDSLVASICALYPKELFYPISKAFSAGLIDKSFISMEDVETIIHEESIDSCLQEVFSSTDLIDDTLEEMEKWLERFPFES
What are the official names of this protein?
Uncharacterized protein TC_0475.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0206/CT203/TC_0475 family.
Protein: FUCM_ECO7I
Sequence: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_PYLLI
Sequence: MSLNIRVIAPDGLIWDTTAEGVVLPSLTGQLGILTGHAPLITSLEIGILRIKTNSKWTPIIVLGGFAVIKDDEVLVLISGVEEVIKEDYSKAKSILAKAKIDLDSAKTTKEIIDASQELKIASAKVKAFKFI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RL4_LARHH
Sequence: MELKVINQQGQAVESLQAAETLFGREYNEALVHQVVTAYLANARAGNRAQKDRSEINKSTKKPFRQKGTGRARAGRASSPLWRGGGKVFPNSPDENFSHKVNRKMFRAGMAAILSELLRSDRLVIIDDIKVDSPKTKEFAAKAKALGLENALVITGELDENLYLSSRNLSNVLVIEASQADPYSLVRFDKVVVTRDAVKQFEEQWA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RISB_LEPBA
Sequence: MTAQLEGLRIGNGQKHCVIVSKFNEFITESLLKGAKDAYRQHGVAESDVTVIYVPGAFELPQTVKRVLGSKKYQFSAIVCLGAVIRGATSHYDLVSGEAAKVGSVADGSVPVIFGVITTESIEQAIERAGTKAGNKGYEAATTAIEMANLFKEIG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SSPP_BACSU
Sequence: MTNKNTSKDMHKNAPKGHNPGQPEPLSGSKKVKNRNHTRQKHNSSHDM
What are the official names of this protein?
Small, acid-soluble spore protein P, SASP P.
What is the protein family that this protein belongs to?
Belongs to the SspP family.
What are the subcellular locations of this protein?
Spore core.
Protein: DCUP_BACC1
Sequence: MVRTINETFLKACRGERTDYVPAWYMRQAGRSQPEYRKIKEKYSLFEITHNPELCAYVTKLPVDQYNVDAAILYKDIMSPLPAIGVDVEIKSGIGPVIDNPIRSLQDVEKLGEINPEDDVPYILDTIRLLTTEMLDVPLIGFSGAPFTLASYMIEGGPSRNYHNTKAFMYAEPKAWFALMDKLADMVITYLKAQINAGAKAVQIFDSWVGTVNVADYRVFIKPAMERIFAEVRTMGVPMIMHGVGAAHLVNEWHDLPLDVVGLDWRLPIEEARARGVHKAVQGNMDPSFLLAPWSVIEEHVKGILDQGMKQPGYIFNLGHGVFPEVNPDTLKRLTTFIHEYSKGQLAK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMT5_YEAST
Sequence: MARKLKGKIGSKGLKGALLRHKAKVKLVRNIESKQKHELRKKNSSANNKTVKRNQEFQKLNQGKVMPFEKDETLMLCGEGDFSFARSIVEQNYIESDNLIITSYDNSVNELKLKYPHTFEENYQYLKDLNIPIFFQIDVTKLVKSFKISKNNTWFKIINRLSDHRWGNKPLQNIVFNFPHNGKGIKDQERNIREHQDLIFNFFQNSLQLFNLINTKIQNDTLRYTQGYDLNEDTPQAKKLTAEGYGNIILSLFDGEPYDSWQIKLLAKKNGLTLSRSSKFQWENFPGYHHRRTNSEQDTTKPAKERDARFYIFSKYVSNSSKHNRKSKKDTDSDSD
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(3) position of uridine 2634 (m3U2634) in 25S rRNA.
What are the official names of this protein?
25S rRNA (uridine(2634)-N(3))-methyltransferase, Base methyltransferase of 25S RNA 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. BMT5 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TXK01_LYCSI
Sequence: MFSTSDQVSKMNSRILSALLILGIATCVIAGGFCPKSRHPQCNLSYKINDCCAQSDCRVGSVCCVEGCGNVCRAESDTPLGEKFVDGSECKHGHVFPKKWYQFW
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
U20-lycotoxin-Ls1a, Toxin-like structure LSTX-Q1.
What is the protein family that this protein belongs to?
Belongs to the venom protein 11 family. 02 (wap-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CPESY_DROME
Sequence: MIGPSSQISKILLTLLFLLIIFYVFMDVELYLRIHNYAIERNYHTNVSLPASVVGPSTSESGSGSIGGSSSSSSSSSSSTSTKLPTAGDRQPSYEDHTWISCDINPLCHVTVKAILLDHTNHYLFAPLATMFDNVIGFSRSTFITPNMISFFHVGVACLAGKLVASDSLGYRRLGVLLFQIRTFLDDLDGHVARVRKHIRGERSEIGTSGYYVDGLCDGLGCIALLLGIFFYLKNNPPRRGYSIIPMSDSKLPEPTMMIPKMKATTRKVAKNVISFTGQLLLSSTAWNRYIAVYQNMLEREDVSGNQSHCQDYVFKSTWFFCVAWMWRIVNVHALLHCVLLSIFCDKLWDFLRAIRYSGYIILLVAICLTEMHILEAQNYIFNSTACSNISL
What is the function of this protein?
Catalyzes the biosynthesis of ceramide phosphoethanolamine (CPE) through the transfer of a phosphatidyl head group from cytidine 5'-diphosphate (CDP)-ethanolamine on to the primary hydroxyl of ceramide.
What are the official names of this protein?
Ceramide phosphoethanolamine synthase, CPE synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Golgi apparatus membrane. Cell membrane. Note=The majority of protein localizes to the Golgi apparatus.
Protein: SPT4H_XENLA
Sequence: MALETVPKDLRHLRACLLCSLVKTIDQFEYDGCDNCDAYLQMKGNREMVYDCTSSSFDGIVAMMSPDDSWVSKWQRITNFKPGVYAVSVTGRLPQGIVRELKSRGVVYKSRDTAIKT
What is the function of this protein?
May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.  Probably enhances transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT4, DRB sensitivity-inducing factor small subunit, DSIF small subunit.
What is the protein family that this protein belongs to?
Belongs to the SPT4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1461_PASMU
Sequence: MKKNTLFLGLVFIGILTFLVNLLAKTPFALNANLSALTIAILLGILFGNTFYPKISQYTAQGVIFAKGTLLRLGIILYGFRLTLQDISNVGINAIATDTIMLISTFLLTLWLGIRYLKMDKQIVYLTAGGCSICGAAAIMSMQPVTKAESHHVSIAVAVIVIFGTISMFLYPLMYPYLATWLNEHQFGIYIGSSVHEVAQVYAAGGNISPAVADTAVISKMIRVMMLAPFLLLVSWLLTKQNDQAKTTNISIPWFAFLFILMAVINSFSLIPAHIVAWIVEIDSLLLIAAMTALGLTTHISAIKQAGIKPLILGALVLCWLVIGGFFVNVGISQLF
What are the official names of this protein?
UPF0324 membrane protein PM1461.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LILIP_NOSS1
Sequence: MDLNTYLKLLNLLDSESQKIMLELQAMFSAAGLALRGRGTHTDGIIVKGNLTVLHSSDVPSHSLFTPGKKYDVIFRHANIVGGAKDDALINGRGSAIRIGNIGDDLSKPRLLDLVLNTGEVFGLPTARLYHQFFGSDFHQKSDMLASGSLRRYAVEAALRNPDSFTELYYHTQLCYEWVDSKKKSRYARFRLLNPNQSTEGGLLDDSVEIGPRLVLPRKRGDTREKNYLRNEFRQRLTDGNIVEYVLQAQFRSIEDVAVDCSNIWDPNTYPWLDIAAIVLNQDESENDYYQEIAYNPGNTHYDLKLPNSYSVDDFASLGVSGALVHYFGSIVRAERTQYLYGSKDDLPGKPVYFPLPVTEIPSKRFLFLLEKYNFLTDNSYPSDGEHDKIEALVSAMPTTALDLAVGTTDPTDIPDSYFLERRLNGYNPGAIRESSGQEGWTHELTHNLAKYDIKPGLHFPDFVQCRLFVDKQNGVKLHSIKIDDHEITPCQEQWQYAKRTYLQAEFLSQELKLHLARCHFNIEQYVMAIKRRLAPTHPVRAFINPHLEGLIFINSSAVPKIIGSTGFIPIASMLTQGSIVDVMKNELSKLSYMWNPIADLPRDIPGDLFTPAATAYWELLNNYVEQGLLQPFEDELRTEVNAIQVDELFAELKERSLYSGDQPPKYDSSELKSLLMYIIYHSSFLHSWANFKQYDDAGNPNHVSMGDYSQYDQQTQDKIRFSQRSLTWVLSSIRYNSVAVYGSDLLKQLIREKSSILEPGLPLEDLMMSINI
What is the function of this protein?
Catalyzes the conversion of alpha-linoleate to (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate in oxylipin biosynthesis.  Also converts alpha-linoleate to (9R,10E,12Z)-9-hydroperoxyoctadeca-10,12-dienoate.
What are the official names of this protein?
Linolenate 9R-lipoxygenase, NspLOX.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
Protein: PRA15_HUMAN
Sequence: MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC
What are the official names of this protein?
PRAME family member 15.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
Protein: GLYG5_SOYBN
Sequence: MGKPFFTLSLSSLCLLLLSSACFAITSSKFNECQLNNLNALEPDHRVESEGGLIETWNSQHPELQCAGVTVSKRTLNRNGSHLPSYLPYPQMIIVVQGKGAIGFAFPGCPETFEKPQQQSSRRGSRSQQQLQDSHQKIRHFNEGDVLVIPLGVPYWTYNTGDEPVVAISPLDTSNFNNQLDQNPRVFYLAGNPDIEHPETMQQQQQQKSHGGRKQGQHRQQEEEGGSVLSGFSKHFLAQSFNTNEDTAEKLRSPDDERKQIVTVEGGLSVISPKWQEQEDEDEDEDEEYGRTPSYPPRRPSHGKHEDDEDEDEEEDQPRPDHPPQRPSRPEQQEPRGRGCQTRNGVEENICTMKLHENIARPSRADFYNPKAGRISTLNSLTLPALRQFGLSAQYVVLYRNGIYSPDWNLNANSVTMTRGKGRVRVVNCQGNAVFDGELRRGQLLVVPQNPAVAEQGGEQGLEYVVFKTHHNAVSSYIKDVFRVIPSEVLSNSYNLGQSQVRQLKYQGNSGPLVNP
What is the function of this protein?
Glycinin is the major seed storage protein of soybean (PubMed:2485233).  Glycinin basic peptides (GBPs), and, to a lower extent, glycinin exhibit antibacterial activity against Gram-negative and Gram-positive bacteria (e. g.  L. monocytogenes, B. subtilis, E. coli and S. enteritidis) by forming pores and aggregating in transmembranes, leading to membrane permeability and, eventually, cell death (PubMed:22236762, Ref. 15, PubMed:28590128).
What are the official names of this protein?
Glycinin G5, Glycinin 11S G5, Glycinin A3B4.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Endoplasmic reticulum. Protein storage vacuole. Note=Hexamers are assembled in the endoplasmic reticulum and later sorted to the protein storage vacuoles (PubMed:29348620). Cotyledonary membrane-bound vacuolar protein bodies.
Protein: K1C17_HUMAN
Sequence: MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKKEPVTTRQVRTIVEEVQDGKVISSREQVHQTTR
What is the function of this protein?
Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity).  Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity).  Modulates the function of TNF-alpha in the specific context of hair cycling.  Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity).  Involved in tissue repair.  May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial 'stem cells'.  Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity).  May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
What are the official names of this protein?
Keratin, type I cytoskeletal 17, 39.1, Cytokeratin-17, CK-17, Keratin-17, K17.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOR_ECOL6
Sequence: METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNNHSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKLAATLVEPDQTLFFDCGTTTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQTLNNFCPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPARMGDLKRFDIVVSDCCPEDEYVKYAQTQRIKLMY
What is the function of this protein?
This protein is one of the repressors that regulate the expression of deoCABD genes, which encode nucleotide and deoxy ribonucleotide catabolizing enzymes.  It also negatively regulates the expression of nupG (a transport protein) and tsx (a pore-forming protein).  The inducer is deoxyribose-5-phosphate (By similarity).
What are the official names of this protein?
Deoxyribose operon repressor.
Protein: HEM6_FRAT1
Sequence: MQEKISKFEDFLTQLQQNITTALEQHETNAAKFISDKWQKPDTHDQKLKGYGNSMIIEGGEIFEKGVVAFSRVHGSELPPSATAKRQELAGKSFIATGLSLVIHPRNPFVPTSHANFRIFIAGADTDNPIWWFGGGFDLTPYYPFEEDAIHWHQTAKNICDKHDKTYYPKFKKWCDEYFYLKHRDECRGVGGLFFDDLNDKSFDECFNFVTDCANSYLDAYIPIVAQRKNIEYSQKHKDFQLYRRGRYVEFNLVFDRGTIFGLQSGGRTESILSSMPPIATWKYNWQPELGSEEEKVYQYIKPRDWIK
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGR1_METBU
Sequence: MKDQYDLVVVGAGPAGSIAATTAAKKGLSVLMLEKRQEIGEPVRCAEGVGKKRLRQHIELDEKWLCGEVSSAKIISPNGTTLTMAEEDAGSEVGYVLDRKIFDRTLVELSGEAGVDIMVKARVTGLIIEENTVCGVEMMHLGKTYSIRSKLVIGADGVESKVGRWAGIDTSLKPSHIETCAQFLVSGVDIDQSSCYFYMGNKVAPGGYVWVFPKGNNMANVGIGILGSRAGEKKPIEYLTDFVEANYPNGSIIEQVAGAVPASGPIEKTIANGLMLVGDAARQSDPFTGGGISNAMDAGLYAGEVAAEAIAQDDVSEKILQKYEKRWRGSFGNEIANNLIVKETFFSLSDEDLDSLALSIKDVDFKKMDLIDFIAALFKANKKLLWNLRPLFTQKLKQKFSGLTKFKR
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase 1, DGGGPL reductase 1, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase 1, Geranylgeranyl reductase 1, GGR 1.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.