PharMolix/UniProtQA huggingface dataset:
Protein: SRY_ZALCA
Sequence: MFGVLNSDDHRAAIQHRNILAFGRTSSELWTSNPTSNYWCETRGNGRDSGQNRVRRPMNAFMVWSRDQRRKVALENPQMQNSEISKQLGYQWKMLTEAEKWPFFEEAQRLQAVHREKYPDYKYRPRRKALPQKSDKLLPAASSSLLCRQVLVDKSYPFTYRDSCSRATHSHMEDQLSSSQPVNIANSLLQQEHHYSSTSLRGSPETLATHLSADPPFYPK
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: LPRE_MYCBO
Sequence: MPGVWSPPCPTTPRVGVVAALVAATLTGCGSGDSTVAKTPEATPSLSTAHPAPPSSEPSPPSATAAPPSNHSAAPVDPCAVNLASPTIAKVVSELPRDPRSEQPWNPEPLAGNYNECAQLSAVVIKANTNAGNPTTRAVMFHLGKYIPQGVPDTYGFTGIDTSQCTGDTVALTYASGIGLNNVVKFRWNGGGVELIGNTTGG
What are the official names of this protein?
Putative lipoprotein LprE.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL34_BACSU
Sequence: MKRTFQPNNRKRSKVHGFRSRMSSKNGRLVLARRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DDX46_DANRE
Sequence: MGRESRHYRKRSSSRGRSGSLSKSRSPDSKRSKKDDRTASRTHSRRERSRSRERRRSRERKRQRRSSRDRRRSRSRERRRSKSRSRGRSKEKPENGDQTADKKKIKEEKEEEKPEDQDFDQNTLEEEMRKRKERVEKWREEQRKTAMENIGEIKKELEEMKQGKKWSLEDDDEEQDKAAEAEESERMEEEEVGEEVDPLDAYMEEVKEEVKKFNMGTMKGANDKKGGMSVTKVVTVVKTKKMPHATKKKGELMENDQDAMEYSSEEEEVDLQTALTGFQTKQRKVLEPVDHQKIQYEPFRKNFYVEVPELARMSPEEVSEYRLELEGISVKGKGCPKPIKTWVQCGISMKVLNALKKHNYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQRPVGEAEGPLAVIMTPTRELALQITKECKKFSKSLALRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANNGRVTNLRRVTYVVIDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRTMEALARRILSKPVEVQVGGRSVVCSDVEQHVIVIEEEKKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCMSLHGGIDQYDRDSIINDFKNGACRLLVATSVAARGLDVKQLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEGQARYSGDILKALELSGSSVPAELEQLWTNFKEQQKAEGKIIKSSSGFSGKGFKFDETEHALANERKKLQKWALGLHDSDDEDTALDIDEQIESMFNSKKRVKDFSAPGSVSAGSAGGVSGSVSAVSGLGSLSTPSAGNIQKLEIAKKLALRIQAQKNLGAEAQDVMQQATNAILRGGTIIAPSVSAKTIAEQQAEKINAKLNYTPVEKLEEERQAAEAAETVKRYEEELEINDFPQTARWKVTSKEALQRIGEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTSKGRYKVL
What is the function of this protein?
Plays an essential role in splicing, either prior to, or during A complex formation.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX46, DEAD box protein 46.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, Cajal body. Note=Present in Cajal bodies (CBs) and nuclear speckles.
Protein: COAA1_CHICK
Sequence: MHLQISLLLLFCLNIVHGSDGYFSERYQKQSSIKGPPHFLPFNVKSQGVQMRGEQGPPGPPGPIGPRGQPGPAGKPGFGSPGPQGPPGPLGPPGFSTVGKLGMPGLPGKPGERGLNGEKGEAGPVGLPGARGPQGPPGIPGPAGLSVLGKPGPQGPPGAQGPRGPPGEKGEPGVPGINGQKGEMGFGVPGRPGNRGLPGPQGPQGLPGSAGIGKPGENGLPGQPGMKGDRGLPGARGEAGIPGPQGPPGEPGEVGIGKPGPMGPPGPAGIPGAKGLPGPAGLPGSPGLPGFGKPGLPGMKGHRGPEGPPGFPGPKGDQGPAGVPGELGPAGPQGNMGPQGLKGLPGENGLPGPKGDMGPVGPAGFPGAKGERGLPGLDGKPGYPGEQGLPGPKGHPGLPGQKGDTGHAGHPGLPGPVGPQGVKGVPGINGEPGPRGPSGIPGVRGPIGPPGMPGAPGAKGEAGAPGLPGPAGIVTKGLRGPMGPLGPPGPKGNSGEPGLPGPPGPPGPPGQSTIPEGYVKGESRELSGMSFMKAGANQALTGMPVSAFTVILSKAYPGATVPIKFDKILYNRQQHYDPRTGIFTCRIPGLYYFSYHVHAKGTNVWVALYKNGSPVMYTYDEYQKGYLDQASGSAVIDLMENDQVWLQLPNSESNGLYSSEYVHSSFSGFLFAQI
What is the function of this protein?
Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage.
What are the official names of this protein?
Collagen alpha-1(X) chain.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: NANR_ECO57
Sequence: MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.
Protein: AZOR_FRAAA
Sequence: MPNLLHVDASLAQEGSTSRSLAATYIDAWRAAHPDGTVTYRDLALTPPPHLDWATLSAAFTPPEQHTPEQTEGVKLREELIGELEAADELLLSLPMYNYSVPSTFKAWVDQVILVGRTLQQPPAESVLTGDRVTVIATQGGSYGVGTPKEGWDHQLPFIAHVLESLGATDVELVRVEMTLAPVNPALADFTDVYERSRAAGESALRARAAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: HEMH_NEIMB
Sequence: MLPFFPEPSLSYTQQNRTAVLLLNLGTPDAPTAQAVRPYLKSFLTDRRVVELPKWLWYPILHGLVLTLRPKKSAHAYEKIWFKEGSPLEVYTARQAAALAKRMPDLIVRHAMTYGNPSVADVLSELKAQGAGRLLVIPMYPQYAASSSGAAVDKVCEQLLLQRNQMSVRTVSRFYDDTGYIDAMKNHILRYWAEHGRGKKLMLSFHGVPQKHHDLGDPYPDECRHTAKLLAEALELTEDQYVVSFQSQFGRAKWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLETMEEIALMGREQFYEAGGKSYRYIPCLNDNPDWIDALVALAEENLGSWR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_METAC
Sequence: MKIAIIQFGGTNCDMDVLHVLKDVVGVDAETVWYKEENLTGFDGVVVPGGFSYGDYLRAGAIAARTPIMDSVKKIAAEGKPVLGICNGFQVLTEARLLAGALTTNEYPKFRCHWTNLRVETADTPFTSKFRKGEVIRMPIAHMEGKFYAEESTLAELDENEQVVFRYVDEKGRVTDEANPNGSLENIAGILNASRNILGLMPHPERASESILGSDDGRKVFESMADYITENF
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_DESAL
Sequence: MSCIKNSFEALKAKNEKALVGFVTAGDPDFGKSVEIVKAMCEGGMDVLELGIPFSDPTADGPVIQRSSQRALSSGMSLPKVLEMVKIVRGFTKIPIVLFGYYNPIFSYGGKRFYEDALAAGADGVLIVDLPPEESAELTSLWEGDDFDFIRLVAPTTGQDRMKQIAGEASGFIYLVSMTGVTGSQGLDSSKVADVNAPLKAVTDLPVCVGFGISTPEHVKAVAAVSDGVVVGSAFERLIEENLENRGLHTMVQEYTESLKAATRG
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: C640_CONCL
Sequence: MSGSGVLLLTLLLLVPLSALAKECSMYYCSGGDFCCPGLKCGDPTGKKICIEPGK
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal6.40, O3_cal6.2.
What are the subcellular locations of this protein?
Secreted.
Protein: RL29_RHILW
Sequence: MKASDVRGFTADQLKDELAKLKKEQFNLRFQKATGQLEKSSRINEVRKDIARVKTIARQKAAEVKA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PDUW_KLEP7
Sequence: MTYKIMAINAGSSSLKFQLLNMPQGALLCQGLIERIGLPEARFTLKTSAQKWQETLPIADHHEAVTLLLEALTGRGILSSLQEIDGVGHRVAHGGERFKDAALVCDDTLREIERLAELAPLHNPVNALGIRLFRQLLPAVPAVAVFDTAFHQTLAPEAWLYPLPWRYYAELGIRRYGFHGTSHHYVSSALAEKLGVPLSALRVVSCHLGNGCSVCAIKGGQSVNTSMGFTPQSGVMMGTRSGDLDPSILPWLVEKEGKSAQQLSQLLNNESGLLGVSGVSSDYRDVEQAADAGNERAALALSLFAERIRATIGSYIMQMGGLDALIFTGGIGENSARARAAICRNLHFLGLALDDEKNQRSATFIQADNALVKVAVINTNEELMIARDVMRLALPQARELAVSA
What is the function of this protein?
Works with phosphate acetyltransferase (pta) to capture exogenous propionate and regenerate propionyl-CoA during degradation of 1,2-propanediol (1,2-PD).
What are the official names of this protein?
Propionate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family. PduW subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1431_STAA2
Sequence: MATWLAIIFIVAALILGLIGGFLLARKYMMDYLKKNPPINEEMLRMMMMQMGQKPSQKKINQMMTMMNKNMDQNMKSAKK
What are the official names of this protein?
UPF0154 protein SaurJH1_1431.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PYRH_FRATW
Sequence: MSNDSSECSQKLPKLKRILLKLSGESLSADQGFGINVESAQPIINQIKTLTNFGVELALVVGGGNILRGGRANFGNKIRRATADSMGMIATMINALALRDMLISEGVDAEVFSAKGVDGLLKVASAHEFNQELAKGRVLIFAGGTGNPFVTTDTTASLRAVEIGADALLKATTVNGVYDKDPNKYSDAKRFDKVTFSEVVSKELNVMDLGAFTQCRDFGIPIYVFDLTQPNALVDAVLDSKYGTWVTLD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_CHLL3
Sequence: MSFNALPQSSMPLLMGNSLNAWSDALTGFAPMGLPLGLLVIAAIPLVFIALYALTYGVYGERKISAFMQDRLGPMEVGKWGILQTLADILKLLQKEDIVPTSADKFLFVIGPGVLFVGSFLAFAVLPFGPAFIGANLNVGLFYAIGIVALEVVGILAAGWGSNNKWALYGAVRSVAQIVSYEIPAAIALLCGAMMAGTLDMQEINVLQSGPWGFAHFFLFQSPIAWLPFLIYFIASLAETNRAPFDIPEAESELVAGYFTEYSGMKFAVIFLAEYGSMFMVSAIIAIVFLGGWNSPLPNIGSLALNDLTTGPVWGAFWIIMKGFFFIFVQMWLRWTLPRLRVDQLMYLCWKVLTPFAFVSFVLTAIWMIYVP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IFT81_MOUSE
Sequence: MSDQIKFIVDSLNKEPFKKNYNLITFDSLGPMQLLQVLNDVLAEIDPKQDVDIREEMPEQTAKRMLNLLGILKYKPPGNATDMSTFRQGLVIGSKPVIYPVLHWLLQRSNELKKRAYLARFLIKLEVPSEFLQDETVADTNKQYEELMEAFKTLHKECEQLKTSGFSTAEIRRDISAMEEEKDQLMKRVERLKKRVETVQNHQRMLKIARQLRVEKEREEFLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRHAAADAKPESLMKRLEEEIKFNSYMVTEKFPKELESKKKELHFLQKVVSEPAMGHSDLLELETKVNEVNTEINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQETKEKLASLEREVLVKTNQTREFDGTEVLKGDEFKRYVSKLRSKSTVFKKKHQIIAEFKAEFGLLQRTEELLKQRQETIQHQLRTIEEKKGISGYSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLNSLVSEKKSALAPVIKELRQLRQKCQELTQECDEKKAQYDSCAAGLESNRSKLEQEVRGLREECLQEESKYHYTNCMIKNLEVELRRATDEMKAYVSSDQQEKRKAIREQYTKNITEQENLGKKLREKQKAVRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSPASIGQVIQEGGEDRLVL
What is the function of this protein?
May play a role in development of the testis and spermatogenesis.
What are the official names of this protein?
Intraflagellar transport protein 81 homolog, Carnitine deficiency-associated protein expressed in ventricle 1, CDV-1.
What is the protein family that this protein belongs to?
Belongs to the IFT81 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm.
Protein: EFTS_CYAP4
Sequence: MAEITAQLVKQLRDKTGAGMMDCKKALQETGGEMEKAIDWLRQKGLASAGKKAGRLTAEGLVDSYIHTGGRIGVLVEVNCETDFVARNEAFRSLVQDIAKQIAACPNVEYVSIDEIPPATVEREKAIAMGSDALKGKPENVKEKIVQGKMDKTLRELCLLDQPFIRDQSITVEELIKQAIAQLGENVKVRRFVRFVMGEGIEKEEANLAEEVAAQIAAKEAPPAVVEAPVAETPEPAVAETPEAKPAATESKPAKSKSAKKKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_CHLPB
Sequence: MAVQQKIRIKLKSYDHSLVDKWAVKIIDVVKQTDAIIFGPIPLPTKTHVYTVNRSPHVDKKSREQFSFSSHKRLIEIIPTGRTIDMLMKLELPSGVDVEIKS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: AAER_ECOLI
Sequence: MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK
What is the function of this protein?
Activates transcription of the aaeXAB operon.
What are the official names of this protein?
HTH-type transcriptional activator AaeR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RPOB_STRPC
Sequence: MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVGRYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKFVYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIVWLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQHNGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIADGPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SSN3_CRYNJ
Sequence: MATIPGGGTIMDPMHLYRARRDKERRGVLKTYKILGFISSGTYGRVYKAVLLPPPKTASAKSALPSSTRAALSLPKDKLPSPSFTEDSDPLNNPEMCMRPGDRPAKRGDVFAIKKFKPDKEGDVLTYAGISQSGAREIMLNRELHHRNLVSLREVILEDKSIYMVFEYAEHDFLQIIHYHSQTARASIPPSTLRRLLHQLLCGVHFLHSNFVLHRDLKPANILVTSQGVVKIGDLGLARLWHKPLAQQGLYGGDKVVVTIWYRAPELILGAKHYTAAVDIWAVGCIYAELLSLRPIFKGDEAKMDGKKSLPFQRDQMGKICEVLGPVKPEQWPGIVHMPEYRTYQATGPYPHSNPLAPWYHARSNSSEGYDILVKMFEWDPARRITARDALRHPWFQEEGGVDTKSVFEGSSITYPTRRVTHEDNGDAKMGSLPQSMAGGRLPSSSNFRPASGNIVQPAARKKARI
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase SSN3, Cyclin-dependent kinase 8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL331_LIMRJ
Sequence: MSQKKVALECTKCGARNYTITANPQRQERLELRKFCKHCGEYTIHRESR
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ATPD_PEDPA
Sequence: MSLDKTTIAKRYSKALFEIVSEKGQRDETRAELNQIQQVFNDNEGLGKILTDKGLEQNQKLEILNILTKDASNYVGNLIKMTFDYGRMDYLTAIIDEFNNLCDADEKIVRAKVVSAIPLSDQQLDKMAEQFAKRLKVSEVVLDSEVDDSIIGGAIIKTDSLIYDGSIQTQINQIRQRLIG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RECO_PORG3
Sequence: MIIVSRAIVLHNTAYNDSYSIAHLFSRESGRVSYLIPRSSKRGKSGGSLRLLISPLNELEITAEHKQHRDLHFIKEAKLCSLHGRIQSDPVRNSIALFLAEFLYLILRLPEADTNLYDFVAFSIDKLEEMDGPMANFHLAFLFRLLVPLGLIPDLQFGGSVIPRWFDPADGRFVPNAPAHGRGIPPHQSTYLQLFRRITFDNMKAFRLSRAERRQVLDYLVDYYRFHLPPFPLLKTPDILSTLFD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: YQGF_BLOPB
Sequence: MRDVNCVGIVMGFDFGTKHIGVAIGQKLTCTAQPLTVLQSQSGVPNWKRIRDIYNTWKPMIFVVGLPLKIDGSEQPITILAKIFAIQLKELFPVPVKMHDERFSTSEARLNYFKYYHDDLCARSNIKINAIAAGVILKSWLNKS
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_STUS1
Sequence: MPDYRSKTSTHGRNMAGARALWRATGMKDEDFKKPIIAIANSFTQFVPGHVHLKDMGQLVAREIEKHGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAIVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKTKLANHGLDLVDAMVVAADDSCSDEKVAEYERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTTLATHADREQLFLRAGRIAVELCKRYYQDGDESVLPRNVASRKAFENAMTLDIAMGGSTNTILHLLAAAQEAEVDFDLRDIDALSRKVPQLCKVAPNIQKYHMEDVHRAGGIFSILGELARGGLLHTDASTVHSPSMADAIAEWDITQTQDEAVHTFFKAGPAGIPTQVAFSQATRWPSLDLDRAEGCIRSVEHAYSQEGGLAVLYGNIALDGCVVKTAGVDESIHVFEGTAKIFESQDSAVKGILNDEVKAGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKECALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVQDGDKVLIDIPNRSIQLQVSDEELAHRRIEQDKKGWKPAQPRARKVSTALKAYALLATSADKGAVRDKAMLDG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: IFT81_HUMAN
Sequence: MSDQIKFIMDSLNKEPFRKNYNLITFDSLEPMQLLQVLSDVLAEIDPKQLVDIREEMPEQTAKRMLSLLGILKYKPSGNATDMSTFRQGLVIGSKPVIYPVLHWLLQRTNELKKRAYLARFLIKLEVPSEFLQDETVADTNKQYEELMEAFKTLHKEYEQLKISGFSTAEIRKDISAMEEEKDQLIKRVEHLKKRVETAQNHQWMLKIARQLRVEKEREEYLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRQAAADAKPESLMKRLEEEIKFNLYMVTEKFPKELENKKKELHFLQKVVSEPAMGHSDLLELESKINEINTEINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQEAKEKLASLEREASVKRNQTREFDGTEVLKGDEFKRYVNKLRSKSTVFKKKHQIIAELKAEFGLLQRTEELLKQRHENIQQQLQTMEEKKGISGYSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMKAYISSDQQEKRKAIREQYTKNTAEQENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQTSIGQVIQEGGEDRLIL
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium.  Binds tubulin via its CH (calponin-homology)-like region (PubMed:23990561).  Required for ciliogenesis (PubMed:27666822, PubMed:23990561).  Required for proper regulation of SHH signaling (PubMed:27666822).  Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella (By similarity).
What are the official names of this protein?
Intraflagellar transport protein 81 homolog, Carnitine deficiency-associated protein expressed in ventricle 1, CDV-1.
What is the protein family that this protein belongs to?
Belongs to the IFT81 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm.
Protein: CC28B_MOUSE
Sequence: MEDKKKKRSPKPCLTQPAQAPGTLRRVPVPTSHSGSLALGLPHLPSPKQRAKFKRAGKEKCRPVLAGGGGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEEEEEDGVTEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEDQPAA
What is the function of this protein?
Involved in ciliogenesis.  Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex.  Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation.  Does not seem to modulate assembly and function of mTORC1 complex.
What are the official names of this protein?
Coiled-coil domain-containing protein 28B.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=It localizes near centrosomes and basal bodies.