PharMolix/UniProtQA huggingface dataset:
Protein: ENLYS_BPT5
Sequence: MSFKFGKNSEKQLATVKPELQKVARRALELSPYDFTIVQGIRTVAQSAQNIANGTSFLKDPSKSKHITGDAIDFAPYINGKIDWNDLEAFWAVKKAFEQAGKELGIKLRFGADWNASGDYHDEIKRGTYDGGHVELV
What is the function of this protein?
Endolysin with L-alanyl-D-glutamate peptidase activity that degrades host peptidoglycans and participates with the holin in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles.  Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer by hydrolyzing the link between L-alanine and D-glutamate residues.
What are the official names of this protein?
L-alanyl-D-glutamate peptidase, Endolysin, Lysozyme.
What is the protein family that this protein belongs to?
Belongs to the peptidase M15C family.
Protein: ACP_AEDAE
Sequence: MRNSIYKLIMFAVLCMVLTSSLSYAQVTFSRDWNAGKRSLAEAAQSTGDCAAIWRSVTNLCAAVTKNIQHLTMCEARALMKNLQSEDASMENNGGGGLPLFSNGHL
What is the function of this protein?
Neuropeptide with neuromodulator or neurotransmitter role that activates the adipokinetic hormone/corazonin-related peptide receptor (ACPR) (Probable).  May function in regulation of post-ecdysis activities (Probable).  Does not activate the A. gambiae adipokinetic hormone (AKH) and corazonin (CRZ) receptors (Probable).
What are the official names of this protein?
Adipokinetic hormone/corazonin-related peptide, ACP, AKH/CRZ-related peptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: LSR_RAT
Sequence: MAPAAGACAGAPDSHPATVVFVCLFLIIFCPDPASAIQVTVSDPYHVVILFQPVTLPCTYQMSNTLTVPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFEQTAWGDSGVYYCSVVSAQDLDGNNEAYAELIVLGRTSEAPELLPGFRAGPLEDWLFVVVVCLASLLLFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSIYTHLSPAKTPPPPPAMIPMGPPYGYPGDFDRHSSVGGHSSQVPLLRDVDGSVSSEVRSGYRIQANQQDDSMRVLYYMEKELANFDPSRPGPPNGRVERAMSEVTSLHEDDWRSRPSRAPALTPIRDEEWNRHSPQSPRTWEQEPLQEQPRGGWGSGRPRARSVDALDDINRPGSTESGRSSPPSSGRRGRAYAPPRSRSRDDLYDPDDPRDLPHSRDPHYYDDIRSRDPRADPRSRQRSRDPRDAGFRSRDPQYDGRLLEEALKKKGSGERRRVYREEEEEEEGQYPPAPPPYSETDSQASRERRLKKNLALSRESLVV
What is the function of this protein?
Probable role in the clearance of triglyceride-rich lipoprotein from blood.  Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (PubMed:10224102).  Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (By similarity).
What are the official names of this protein?
Lipolysis-stimulated lipoprotein receptor, Lipolysis-stimulated remnant receptor.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. LISCH7 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Located at tricellular contacts.
Protein: RISB_BORPA
Sequence: MNPYILTPDLNGEGLHIGIVRARFNEEIGQAQLQACLEELGKLGVDERDVMVVSVPGALELGVALARMAESYEFDALIALGAVIRGETYHFEVVSNESAAAISRIALETGIPVANGVLTVDTDEQAQARAAGKGADCAQVAVEMANLAAALEPEEDDEDEDDEDEDFDDEEDDGR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CP3AE_CAVPO
Sequence: MDLVPSFSLETWVLLALSLVLLYRYATYSHGFFKKLGIPGPKPLPLFGNVLSYRKGMWSFDIECRKKYGNMWGLYDGPQPVLAITEPDMIKAVLVKECYSVFTNRRSLVPVGFMKKAVSLSEDEEWKRIRTQLSPNFTSGKLKEMFPIIKQYGDVLVKNLRQEAEKGKPVQLKEIFGAYSMDIIVATAFGVNVDSLNNPHDPFVSKARKLFRFDFLSPFLLSIVMFPFLTQLYEMLSISIFPRDSLKFFTKFVKKTKENHLESNKKQRVDFLQMMLNSQNFKDTESHKALSDVEILAQSIIFIFAGYETTSSTLSFIMYSLATHPDVQKKLQQEIDKTLPNKAFPTYDVMMEMEYLDMVVNETLRLYPVTNRIERMSKKDFEINGMSFPKGTGVMIPSFALHRDSKYWPEPDEFRPERFSKKNKENIDPYIYMPFGNGPRNCIGMRMALMNLKLALIRLLQNFSFYPCKETQIPLRLGSEALLQPAKPIILKVVSRDETIRGA
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 3A14, CYPIIIA14.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: SDC25_YEAS7
Sequence: MSCTASYAGMTTPVKDKEGHGIPCLQPIDVVECTYQYFTKSRNKLSLRVGDLIYVLTKGSNGWWDGVLIRHSANNNNNSLILDRGWFPPSFTRSILNELHGVPDIGNELEIFQAGLNLKLELSSNPVILSLEDFLDCCRDIEFKEQLAWSPTPVHERKGCCELLYYNQDLDVYCRTLPYLPQNQVETVNDYSSFPAISKIAGKKMPITSSPDLFYLNDCDVVYWYDLTRLVCHYVNLTERDLLANEREKFLTSLDLLTAQITCVYMLFRNLRLVEDSFKKTLKKLIYTLSRFSINANIWFHSTPFEEREAIASQKDPERRSPLLQSILGTFQKFHFLLRLLHFLSNPNELTILPQLTPRFFKDSFNTISWNNPFLRKHLNQHMSHDLPRQMIKAVAGASGIVAENNDEIPASKQGTSCSSETSHHSPSAPFQRRRRGTIFSNVPGSSDESDTIWSKRKKPYPLNEETLSLVRARKEQLDAKLKQMIKSANEYLSNTANFSKMLNFEMNFKTYEEVSGTIPIIDILENLDLTIYLNLRELGDENRVFDEDVAIDDEDKEFLKHSLSSLSYILSDYFNMKQYFHDVVVKFIIVAQHLTLEDPFVFSPMQNDLPTGYYEPMKPSSLNLDNAKDKKNGSQNTDIQEEEDEYEPDPDSLILFHNLINQDSDFNDLKFFNLAHVFKKSCDDYFDVLKLSIEFVNRLILERENLLNYAARMMKNNITELLLRGEEGYGSYDGGETAEKSDTNAVYADSDTKDNDEWRDSQVKLPRYLQREYDSELIWGSNNRIKGGSKHALISYLTDNEKKDLFFNITFLITFRSIFTTTEFLSYLISQYNLDPPEDLCFEEYNEWVTKKLIPVKCRVVEIMTTFFKQYWFPGYDEPDLATLNLDYFAQVAIKENITGSVELLKEVNQKFKHGNMQEATAPMKTLDQQICQEHYWGTLYSTTESILAVDPVLFATQLTILEHEIYCEITIFDCLQKIWKNKYTKSYGASPGLNEFISFANKLTNFISYSIVKEADKSKRAKLLSHFIFIAEYCRKFNNFSSMTAIISALYSSSIYRLEKTWQAVIPQTRDLLQSLDKLMDPKKNFINYRSELKSLHSAPCVPFFGVYLSDLTFTDSGNPDYLVLEHGLKGVHDEKKYINFNKRSRLVDILQEIIYFKKTHYDFTKDRTVIECISNSLENIPHIEKQYQLSLIIEPKPRKKVVPNSNSNNKSQEKSRDDQTDEGKTSTKKDRFSKFQLHKTKKKAPKVSK
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP.
What are the official names of this protein?
Guanine nucleotide exchange factor SDC25.
Protein: RS20_MICLC
Sequence: MANIKSQKKRILTNEKARQRNVAVKSELKTAIRAVDKAVAAGEAEAAAAALRTASRKLDKAASKGVIHKNQAANRKSGIAARVKALLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RISB_METS3
Sequence: MAKYNIGAVVAEFNYDITQMMLGLAKEEAKSRDCEITQVVTVPGVFDMALAIKKLLEKDEIDAVITLGAVIEGATDHDQIVAQHASRKIADLSLEYEKPVALGISGPGMTRLDAHKRVDYGKRAVEAAIKMCDRLNEI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RIMP_SYNAS
Sequence: MVNEFVKKLREDIWQLAEPVIASEGLELVEVECLRMKTRWLVRIYMDREGGVTLDDCSEISNQLGDVLDVHDLPPDPYTLEVSSPGLDRPLVRDKDFVRYQGCEVSIRLEQKVDGIRNFRGRLLEYVEEDGRKILVIEMASKLYRIPRDLIVKANLVYRF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOM_PODAS
Sequence: MKKNNTILYYGCAAQARYASSNHGLLYSPSQAHLFNFSLARTYLNFSNGFRAFSSERKRQNSWKLSVRSIYMDSVNFTKHDFINALLKNFKQGNVYTVLVKVEYLDSSGNRAWCMLNVQKGIIYRNKSDFIELVKEFFDEVYIGYIEYMSRYHAQEVLSIQIMYILNNDSYRQYSLKNINKEKLDKNLVNVKQTKLDFSESLLPLTTNEKFYGKRLTPILDYKKQFVTSLYINGINFIKLVNKKSKDLNQEFINFDSKTRFYRYKLNEIEYIITVSNISKTETVKTIYLMTGFKFKDNILDKELTTKIFSRQIGNTTIEFDGADIINKEIKLKLPIIRLNYKPFTDLNSRIGTFDLETFRDYNSNSAVYALGFSTLSMSKTDKKTSMYYLTKDGNTSHEIIIKCINEMLSSDYRDHIYFTHNLGGYDIIFILHALKLENKIILENKLKGINTIVEDDKKIKVKKKKPISDVNKKSQNKDHYEISTILRDDRILKCVIKVKTPSGYNKITFIDSYNILPDKLDNLAKSFGTEIQKGLFPYEFVKSNTLNYVGITPSIEYYKINNEVISQELYNELIVPQWDLRKQTLHYLERDLLSLLEIINTYNHYVYKRYNVQLTESLTIARLALNIYLKRYLGDNLIPVVLNNSLFTSIKAAYYGGVAEVYRPYGKNLRYYDVNSLYPFVAKNTMPGHECKYIESKKGLKLSELFGFFYCKVTTNNQYLGLLPVHNQGLIMPNGQWYGWYFSEELKFAEVNGYNIEVIKGYQFNKIDNLFSSYVDDLYKIKANSEGSEKLITKFLLNSLLGRFGMSIFKLKTDIVSVEKAKKLAVTNYINSVKAISDTDVLISYNKEISRKLVEEHGLNYIEILNSNSKLDLEKNNSFKDVAVSISAAVTAYARIFMAQTKLDILKNGGNLYYTDTDSIVTDIDLPDNLVGSELGQFKLEFKLKEGFFISAKTYCLILEKEYIKKNKNKDTVIKAKGVFKTSLDVEKFKSLYFNKQDVEAIKSNNKTNYLEGYVNIESGIVKLKHDAYTKRSKIYDNNGLWIDTKPLNYQVSNMLEDTNSKPLNSPNNNDLCALIKYNKPCFDLIKYNKSITDLILYLPTNKAKFINYAQLESMINEAIHESDMRVANHIKMLIYSLTGILYHGKDGTMYIYSPNSKKIYIKYKKNNKWVTFWNIKYHNGYVYIKNKNKFYLYKG
What are the official names of this protein?
Probable DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RADA_METJA
Sequence: MITFIYFFGNIIYYLPIYSYINNYKFMLMVIIMDDLTQLPGVGPTTAEKLKEAGYTDFMKIATASIGELTEIDGISEKAAARIIEAARELCNLGFKSGTEVLSQRKNIWKLSTGSKNLDEILGGGLESQSVTEFAGMFGSGKTQIAHQACVNLQCPERIVADDAIKDEILNEPKAVYIDTEGTFRPERIVQMAEALGLDGNEVLNNIFVARAYNSDMQMLYAENVENLIREGHNIKLVIVDSLTSTFRTEYIGRGKLAERQQKLGRHMATLNKLADIYNCVVIVTNQVAARPDALFGPSEQAIGGHIVGHAATFRIFLRKAKGDKRVAKLYDSPHLPDAEAMFRITEKGIHD
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: RS4A_CLOPE
Sequence: MARYTGATCKLCRREGMKLFLKGDRCYTDKCAFVRRSYAPGQHGASRKKLSNYGTQLREKQKAKRIYGVLEGQFRNTYERAEKMRGIAGENLLKLLEMRLDNVVYRLGYGASRTEARQLVNHGHFLVNGKKVDIASFKVSVNDVITVCEKSRGSERFKMFAENPKALPKWLEANVENFEGKVVAEPAREDIDVPVNETLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4 A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: O13G1_HUMAN
Sequence: MNHSVVTEFIILGLTKKPELQGIIFLFFLIVYLVAFLGNMLIIIAKIYNNTLHTPMYVFLLTLAVVDIICTTSIIPKMLGTMLTSENTISYAGCMSQLFLFTWSLGAEMVLFTTMAYDRYVAICFPLHYSTIMNHHMCVALLSMVMAIAVTNSWVHTALIMRLTFCGPNTIDHFFCEIPPLLALSCSPVRINEVMVYVADITLAIGDFILTCISYGFIIVAILRIRTVEGKRKAFSTCSSHLTVVTLYYSPVIYTYIRPASSYTFERDKVVAALYTLVTPTLNPMVYSFQNREMQAGIRKVFAFLKH
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 13G1, Olfactory receptor OR1-37.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ADD_VIBC3
Sequence: MITSSLPLTDLHRHLDGNIRTQTILELGQKFGVKLPANTLQTLTPYVQIVEAEPSLVAFLSKLDWGVAVLGDLDACRRVAYENVEDALNARIDYAELRFSPYYMAMKHSLPVTGVVEAVVDGVRAGVRDFGIQANLIGIMSRTFGTDACQQELDAILSQKNHIVAVDLAGDELGQPGDRFIQHFKQVRDAGLHVTVHAGEAAGPESMWQAIRDLGATRIGHGVKAIHDPKLMDYLAQHRIGIESCLTSNLQTSTVDSLATHPLKRFLEHGILACINTDDPAVEGIELPYEYEVAAPQAGLSQEQIRQAQLNGLELAFLSDSEKKALLAKAALRG
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: RGS8_HUMAN
Sequence: MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
What is the function of this protein?
Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2 (By similarity).  Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:18434541).  Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 8, RGS8.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane; Peripheral membrane protein; Cytoplasmic side. Perikaryon. Cell projection, dendrite. Nucleus. Note=Detected in Purkinje cell soma and dendrites. Associated with Purkinje cell membranes. Not detected in Purkinje cell nuclei. Detected in the nucleus after heterologous expression. Recruited to the cell membrane in the presence of GNAO1.
Protein: STXB_BP933
Sequence: MKKMFMAVLFALASVNAMAADCAKGKIEFSKYNEDDTFTVKVDGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSGFAEVQFNND
What is the function of this protein?
The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
What are the official names of this protein?
Shiga-like toxin 2 subunit B, SLT-2 B subunit, SLT-2b, SLT-IIb, Verocytotoxin 2 subunit B, Verotoxin 2 subunit B.
What is the protein family that this protein belongs to?
Belongs to the stxB family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL17_STRU0
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTSALQKLFNEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: TRNP1_HUMAN
Sequence: MPGCRISACGPGAQEGTAEQRSPPPPWDPMPSSQPPPPTPTLTPTPTPGQSPPLPDAAGASAGAAEDQELQRWRQGASGIAGLAGPGGGSGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGPRRGRRGRPPALLASALGLGGCVPWGAGRLRRGHGPEPDSPFRRSPPRGPASPQR
What is the function of this protein?
DNA-binding factor that regulates the expression of a subset of genes and plays a key role in tangential, radial, and lateral expansion of the brain neocortex.  Regulates neural stem cells proliferation and the production of intermediate neural progenitors and basal radial glial cells affecting the process of cerebral cortex gyrification.  May control the proliferation rate of cells by regulating their progression through key cell-cycle transition points (By similarity).
What are the official names of this protein?
TMF-regulated nuclear protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCOP_PARDP
Sequence: MADTDDEHASPQNPDNRIELERQAADEAHKAKILAHPPEGPGGDPLHPPVTPRPGATRVVRDRKGGRRVVEVPSTGHSWDGIEEYDNPLPRWWLWTFYATIVWGVLYLIAYPAIPLVNGATQGLLGQNYRSDVAAEIQRFNEANAPIQAKLVETPLEEIAADPELANYTANAGAAIFRTWCAQCHGSGAGGATGYPSLLDNDWLWGGTLEEIHTTVMHGIRDPKDADTRYSEMPRFGIDGLLENAQISQVVNHVLELGGLPHDAALAAEGVEVFADNCSSCHAEDGTGDRAQGAPDLTDAVWLYGSDPATITRIVRDGPFGVMPAWTGRLSEADIVAVAAYVHSLGGGE
What is the function of this protein?
C-type cytochrome.  Part of the cbb3-type cytochrome c oxidase complex.  CcoP subunit is required for transferring electrons from donor cytochrome c via its heme groups to CcoO subunit.  From there, electrons are shuttled to the catalytic binuclear center of CcoN subunit where oxygen reduction takes place.  The complex also functions as a proton pump.
What are the official names of this protein?
Cbb3-type cytochrome c oxidase subunit CcoP, Cbb3-Cox subunit CcoP, C-type cytochrome CcoP, Cyt c(P), Cytochrome c oxidase subunit III.
What is the protein family that this protein belongs to?
Belongs to the CcoP / FixP family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YC51L_SYNY3
Sequence: MDVTIYLRWSAYATIASFIFMVLAFVFRWGFRFRLVGVTSFMTVLTIGIFGLGLGMFDRPTVEGSVKFNRVYDNGANQIVISVPVTVSATEVEATLKQAANNYFSLGRISTDGKEQMVIRARTLIHPQPGLTKPLYLGSAYRTLGTKENDQIEIKLDRKALRELERNQAA
What are the official names of this protein?
Ycf51-like protein.
What is the protein family that this protein belongs to?
Belongs to the ycf51 family.
Protein: YD406_YEAST
Sequence: MTLFSFFLVILSFYYILFSLLGRNYLIFIYIKIIPTVSYFHFNHHFFKLKFRNAKHIIVYFSRKHNFQHQALFVLYYLYSI
What are the official names of this protein?
Putative uncharacterized protein YDR406W-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATG15_PICST
Sequence: MLAAEKRRLLHKTRPVSASEKPGSIYPQRALYLLVCFSIATISLGYLHFIGAIDIGRFGISSVISDLTKQDAVSEPFSLHKEQTSSVHTESDEQTFELKHIFHHGTGPENYRLHRRLDITPSYLAKHSSYFADFSQRLAQKRDDSSVDSENLEDIYNLMDWPDVHKHKNPFTIQLPIKKDHKKGKVVRLKDRHEPGFLDSYLSYALQVKGDPKILNRIALEWEDEIEIDIPNMKDKDTLVSLATISSNAYVKFPKDENEKNKSDWIDVGQWEPDQENVDLNFGWEDIGLRGHVFVSKDNKTVVIGIKGTSGAGLPGGGSDETAGNDKDNDNLLFSCCCARVGYMWTTVCNCYEKTYTCNQDCLEKELLREDKYYQAVLDLYRNVSAIYPPETTNVWVTGHSLGGALASLLGRTYGLPVVAFEAPGEMLATKRLHLPQPPGIPKFMENIWHVGNTADPIYMGVCNGASSTCNVAGYAMETACHTGYQCVYDVVTDLGWRVNLLNHRIHTVIDDIILAYNDTAQCIEQPPCRDCFNWRFTSHDDDVPDEPEMPNPLRPKPKPKPSSSTSDGKNNRISSTATTTISPTSRKADPTSSDISEPSESPKKCLERTWYGWCSKWGYDGDVDDDQ
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase ATG15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: NIKR_ECOUT
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: MCFI_DICDI
Sequence: MVNGEEYVETPNLIHDEETRKDVKFNLGIELLAGTLAGVSSCILFYPLECVEAKLQVQSSSTAVAATMLGLKKNGGSGSGSSSSSSISHQTPNGPIAMAKSILRNEGFKGFYQGVSPTILGNAVNWGVYFSIYRATNHWWNSTDINGNQYQGPAWVGHSVSAITAGVITTAIVNPFWVLKIRLATSKKYSGMKHAFQSILRSEGVGGFWKGVGVSFIGVSEGLFQFVSYEYILNQMKESNLKMNGGELSVGNYLFAGGTARLIAGVLTYPYLLIRSSLQSETCPYKSMSEAVKGIYKTNGIKGFYKGIGPNLARSIPPAAFMLYIVEFFRDTLTNFSQ
What is the function of this protein?
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.  Transports folate across the inner membranes of mitochondria (By similarity).
What are the official names of this protein?
Mitochondrial substrate carrier family protein I, Mitochondrial folate transporter A.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS3_HELPH
Sequence: MGQKVNPVGLRLGINRNWTSRWFPSARTAPSNIDEDNKIRKFLKKELYYAGVSEIVIERAAKKLRVTVVAARPGLIIGKKGVDIEKVKEGLKTLIKKEVSINIKEVKRPQADAQLAAENVATQLEKRVAFRRAMKKVMQAALKSGAKGIKVRVSGRLAGAEIARTEWYMEGRVPLHTLRAKIDYGFAEAMTVYGIIGVKVWIFKGEVLQKGIQFEKKEEAKEEREPRRSRRGRQ
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GNAT5_ARATH
Sequence: MAALSISLAFSVDSLKPTQSTKFGFSSSSHRYPLLYSCKSHRSNLRFAFPPSSVSTATETGEENSKSTGNYAFLEESFRTGRFLSNDELEKLKTLEGFAYFQELESGSMWVRVMRHEEMDSTVHLLAESFGESMLLPSGYQSVLRFLIKQYLIERREVLPHAVTLVGFFRKKVDEFSDDGEEEAVMAGTVEVCLEKRGANASPPSPTPPKESPYICNMTVKEDLRRRGIGWHLLKASEELISQISPSKDVYLHCRMVDEAPFNMYKKAGYEVVKTDTVLVLLMLQRRKHLMRKKLLPLCTNPIVEMVGSDNELTSSANV
What is the function of this protein?
Protein acetyltransferase with dual specificity triggering both N-alpha-acetylation (NTA), with a large spectrum of modified N-termini, including methionine, alanine, serine and to a lower extent threonine and valine as substrates, and epsilon-lysine acetylation (KA).
What are the official names of this protein?
GCN5-related N-acetyltransferase 5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
Protein: NRAM_I57A4
Sequence: MNPNQKTITIGSVSLTIATVCFLMQIAILATTVTLHFKQHECDSPASNQVMPCEPIIIERNITEIVYLNNTTIEKEICPEVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNGTIHDRIPHRTLLMNELGVPFHLGTKQVCVAWSSSSCHDGKAWLHVCVTGDDRNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIKEGKIVHISPLSGSAQHIEECSCYPRYPDVRCICRDNWKGSNRPVIDINMEDYSIDSSYVCSGLVGDTPRNDDSSSNSNCRDPNNERGNPGVKGWAFDNGDDVWMGRTINKESRSGYETFKVIGGWSTPNSKSQVNRQVIVDNNNWSGYSGIFSVEGKSCINRCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.