PharMolix/UniProtQA huggingface dataset:
Protein: CF157_MOUSE
Sequence: MAPKKKPNKGGKEMQGKKIGGKKDASGTKTPELAMVEELKEFYHKQIQDLEDRLARYQRKWDELAVREKLFHQEFEQLANNKKEIVAFLKRTLNQKVDEITDLNDQLQSLEVAKDMEKDAFEAQLAQVRHEFQEIKDQLTTENIALGIKLSSLEEFRLQKEELTEKYLALEEQLHRQEGEYKEYVYNLEKKSVLDKDRLRKEIIQRVNLVATEFRKMATNQMWETTRRAILENNSVTLQLNKVSKHGVQLLQENEQLKGTQNKLCQQLEMLENTQEIMARKNIGHKKIILMLTEKCRQQRKGTEETEQLRLLLSQLEQNFQNVQRDNQTLRSEKDQLEAQLKEKQAEANRLQEELTKEQKIRANLKTVLIQATSMLQDIVHMQTEAEDGDFDVVFQLQRKELLQQLLVLLSSGVVLKTQPDMGSHQDKQPQGLSKESQRITQTSKEGAVSLLQQLSTITTYKPGDLGLVPRRPVRIPLKPQDLRPLSYITRMGICQNTNEIYPSGALKRFRKFTLPRPFLHRK
What is the function of this protein?
Specifically required during spermatogenesis for flagellum morphogenesis and sperm motility (PubMed:27965440).  May be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure (PubMed:27965440).
What are the official names of this protein?
Cilia- and flagella-associated protein 157.
What is the protein family that this protein belongs to?
Belongs to the CFAP157 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: TR105_RAT
Sequence: MLSAAEGILLSIATVEAGLGVLGNTFIALVNCMDWAKNKKLSKIGFLLFGLATSRIFIVWILILDAYAKLFFPGKYLSKSLTEIISCIWMTVNHMTVWFATSLSIFYFLKIANFSHYIFLWLKRRTDKVFAFLLWCLLISWAISFSFTVKVMKSNPKNHGNRTSGTHWEKREFTSNYVLINIGVISLLIMTLTACFLLIISLWKHSRQMQSNVSGFRDLNTEAHVKAIKFLISFIILFILYFIGVAVEIICMFIPENKLLFIFGLTTASVYPCCHSVILILTNSQLKQAFVKVLEGLKFSENGKDLRAT
What is the function of this protein?
Gustducin-coupled cycloheximide receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
What are the official names of this protein?
Taste receptor type 2 member 105, T2R105, Taste receptor type 2 member 9, T2R9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PLF4_RABIT
Sequence: SDDPKESEGDLHCVCVKTTRLVRPGHITXL
What is the function of this protein?
Released during platelet aggregation.  Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.  Chemotactic for neutrophils and monocytes.  Inhibits endothelial cell proliferation (By similarity).
What are the official names of this protein?
Platelet factor 4, PF-4, C-X-C motif chemokine 4.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU1_SULTO
Sequence: MGCQFSVNSKKVRIFDTTLRDGEQAPGIDLTVEQKVKIARKLAELGVDVIEAGFPAASEGEFIATKKILEEVGDQVEVIGLSRANKQDIDKTIDTGISSIHVFIATSDIHLKYKLKMTREQVLDKIYESVRYAKDHGLIVEYSPEDATRTDKDFLLKAVSTAIEAGADRINIPDTVGVMHPFKFHDLIKDVVSVTKDKIVSVHCHNDFGLATANSIAGVMAGARQVHVTVNGIGERAGNASLEEVVMALKKLLGYEVNIKTYKLYETSRLVSELTGVPVPYFKAIVGENAFGHEAGIHVHGVIENPLTYEPISPEEVGNFRRLALGKHSGIHGLKKLLEEQGIYLNDQELREVLNEIKKLAENGEKVNVDVAKEIAIKVSSKKIKV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).  Carries out the first step of the leucine biosynthesis pathway.
What are the official names of this protein?
2-isopropylmalate synthase, IPMS, Alpha-isopropylmalate synthase, Alpha-IPM synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: RS2_RHIME
Sequence: MALPDFTMRQLLEAGVHFGHQTHRWNPKMKPYIFGDRNNVHIIDLAQTVPMLSRALQVVSDTVASGGRVLFVGTKRQASEIIADAAKRSAQYYVNARWLGGMMTNWKTISNSIQRLRKLDEILASEASGFTKKERLNLEREREKLNRALGGIRDMGGTPDLMFIIDTNKESIAIDEAKRLGIPVVAVIDSNCDPDQIDYAIPGNDDASRAIALYCDLIARAAIDGIARQQGASGRDLGASEEVPVEPALEEASEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y985_THEM4
Sequence: MSGHNKWANIKHRKAAQDAKRSKIFTKLIREIIVAAREGGGDPETNPRLRAVIERARAANMPKDTIEKSIKKGTGELEGVDYQEIIYEAYAPAGVALYIYAMTDNKNRTAQELRHLLSKHGGSLAESGSVAWLFERKGIIEIPKDKVADFEEFAMVAIDAGAEDIIEDDPIQVVTAPEKLTEVKDNLASNGFEGEAKVTFIPKNTVKVTGADAEKVLKLISVLEDNDDVQEVYANFDIDDKEMEEIMAKLEG
What are the official names of this protein?
Probable transcriptional regulatory protein Tmel_0985.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M1_I78A3
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDSNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALATCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVITTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: TSAC_SHEB8
Sequence: MLQLHPSDIKDIILQGGVIAYPTEAVYGLGCDPDNDTAIQKLLAVKQRPWQKGLILVASDFQQLLAYVDESQLTAEQLEFAFSKWPGPFTFVMPIKAHVSKYLCGEFDSIAVRVSAHAGVQALCRALNKPLVSTSANLAGEDPALTAAEILADFTGKIDALVLGELGEQRQPSTIIDARSGKILRNGQ
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_CUPPJ
Sequence: MARMVQCIKLNKEAEGLDFPPLPGELGKKIWQSVSKEAWAGWLKHQTMLINENRLNMADARARQYLLKQTEKYFFGEGADEAAGYVPPQA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: SHRM3_HUMAN
Sequence: MMRTTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAAWSGGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQISQGMIGPPWHQSYHSSSSTSDLSNYDHAYLRRSPDQCSSQGSMESLEPSGAYPPCHLSPAKSTGSIDQLSHFHNKRDSAYSSFSTSSSILEYPHPGISGRERSGSMDNTSARGGLLEGMRQADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQGYDKWSNIPRGKGVPPPSWSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSLDQKRLCRPQANSLGSLKSPFIEEQLHTVLEKSPENSPPVKPKHNYTQKAQPGQPLLPTSIYPVPSLEPHFAQVPQPSVSSNGMLYPALAKESGYIAPQGACNKMATIDENGNQNGSGRPGFAFCQPLEHDLLSPVEKKPEATAKYVPSKVHFCSVPENEEDASLKRHLTPPQGNSPHSNERKSTHSNKPSSHPHSLKCPQAQAWQAGEDKRSSRLSEPWEGDFQEDHNANLWRRLEREGLGQSLSGNFGKTKSAFSSLQNIPESLRRHSSLELGRGTQEGYPGGRPTCAVNTKAEDPGRKAAPDLGSHLDRQVSYPRPEGRTGASASFNSTDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCSVLEKVSKFEQREQGSQRPSVGGSGFGHNYRPHRTVSTSSTSGNDFEETKAHIRFSESAEPLGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLSSEPEREPEWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRPRPSSAHVGLRSPEASASASPHTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREATLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSGFGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSVHAQLAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQRTVSSSGCEGKRNEDKEAVSMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDRRERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDFIPKAGALALPPNLTSEPIPAGGCTFSGIFPTLTSPL
What is the function of this protein?
Controls cell shape changes in the neuroepithelium during neural tube closure.  Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers (By similarity).  Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity).
What are the official names of this protein?
Protein Shroom3, Shroom-related protein, hShrmL.
What is the protein family that this protein belongs to?
Belongs to the shroom family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cytoplasm, cytoskeleton. Apical cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin in stress fibers and adherens junctions.
Protein: MUTT_HAEIN
Sequence: MDKKIIQVAAGIIRNEFGQIYLTQRLEGQDFAQSLEFPGGKVDAGETPEQALKRELEEEIGIVALNAELYERFQFEYPTKIISFFFYLVNEWIGEPFGREGQEGFWVEQHALDAGQFPPANAKLIHRLLNETHNFI
What is the function of this protein?
Specifically hydrolyzes both 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to the related monophosphates, thereby cleaning up the nucleotide pools and preventing misincorporation of 8-oxoGua into DNA and RNA.  It prevents replicational errors by removing an oxidatively damaged form of guanine (8-oxo-dGTP) from DNA and the nucleotide pool.  8-oxo-dGTP can be inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions.
What are the official names of this protein?
8-oxo-dGTP diphosphatase, 8-oxo-dGTPase, 7,8-dihydro-8-oxoguanine-triphosphatase, Mutator protein MutT, dGTP pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: TARA_STAAN
Sequence: MTVEERSNTAKVDILGVDFDNTTMLQMVENIKTFFANQSTNNLFIVTANPEIVNYATTHQAYLELINQASYIVADGTGVVKASHRLKQPLAHRIPGIELMDECLKIAHVNHQKVFLLGATNEVVEAAQYALQQRYPNISFAHHHGYIDLEDETVVKRIKLFKPDYIFVGMGFPKQEEWIMTHENQFESTVMMGVGGSLEVFAGAKKRAPYIFRKLNIEWIYRALIDWKRIGRLKSIPIFMYKIAKAKRKIKKAK
What is the function of this protein?
Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
What are the official names of this protein?
N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase, N-acetylmannosaminyltransferase, UDP-N-acetylmannosamine transferase, UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
Protein: ZN407_HUMAN
Sequence: MMDSENKPENDEDEKINKEAQDLTKLSSHNEDGGPVSDVIASFPENSMGKRGFSESSNSDSVVIGEDRNKHASKRRKLDEAEPLKSGKQGICRLETSESSVTEGGIALDETGKETFLSDCTVGGTCLPNALSPSCNFSTIDVVSLKTDTEKTSAQEMVSLDLERESPFPPKEISVSCTIGNVDTVLKCSICGHLFSSCSDLEKHAESHMQQPKEHTCCHCSHKAESSSALHMHIKQAHGPQKVFSCDLCGFQCSEENLLNAHYLGKTHLRRQNLAARGGFVQILTKQPFPKKSRTMATKNVHSKPRTSKSIAKNSDSKGLRNVGSTFKDFRGSISKQSGSSSELLVEMMPSRNTLSQEVEIVEEHVTSLGLAQNPENQSRKLDTLVTSEGLLEKLESTKNTLQAAHGNSVTSRPRPERNILVLGNSFRRRSSTFTLKGQAKKRFNLLGIKRGTSETQRMYMKHLRTQMKTHDAESVLKHLEACSSVQRVCVTTSETQEAEQGQGSARPPDSGLHSLTVKPASGSQTLCACTDCGQVATNRTDLEIHVKRCHAREMKFYCRTCDFSSMSRRDLDEHLHSNQHQQTASVLSCQCCSFISLDEINLRDHMKEKHNMHFLCTPCNLFFLSEKDVEEHKATEKHINSLVQPKTLQSSNSDLVLQTLPLSTLESENAKESMDDSGKASQEEPLKSRVSHGNEVRHSSKPQFQCKKCFYKTRSSTVLTRHIKLRHGQDYHFLCKACNLYSLSKEGMEKHIKRSKHLENAKKNNIGLSFEECIERVCIGANDKKEEFDVSGNGRIEGHIGVQLQEHSYLEKGMLASEELSQSGGSTKDDELASTTTPKRGRPKGNISRTCSHCGLLASSITNLTVHIRRKHSHQYSYLCKVCKYYTVTKGDMERHCATKKHKGRVEIEASGKHSSDIIVGPEGGSLEAGKKNAGSAVTMSDEHANKPAESPTSVLEKPDRGNSIEAEVENVFHSLDGEVNSHLLDKKEQISSEPEDFAQPGDVYSQRDVTGTGENKCLHCEFSAHSSASLELHVKRKHTKEFEFYCMACDYYAVTRREMTRHAATEKHKMKRQSYLNSANVEAGSADMSKNIIMPEEEHQQNSEEFQIISGQPSDTLKSRNAADCSILNENTNLDMSKVLCAADSVEVETEEESNFNEDHSFCETFQQAPVKDKVRKPEEMMSLTMSSNYGSPSRFQNENSGSSALNCETAKKNHEISNDAGELRVHCEGEGGNAGDGGGVVPHRHLCPVTLDGERSAESPVLVVTRITREQGNLESGGQNRVARGHGLEDLKGVQEDPVLGNKEILMNSQHETEFILEEDGPASDSTVESSDVYETIISIDDKGQAMYSFGRFDSSIIRIKNPEDGELIDQSEEGLIATGVRISELPLKDCAQGVKKKKSEGSSIGESTRIRCDDCGFLADGLSGLNVHIAMKHPTKEKHFHCLLCGKSFYTESNLHQHLASAGHMRNEQASVEELPEGGATFKCVKCTEPFDSEQNLFLHIKGQHEELLREVNKYIVEDTEQINREREENQGNVCKYCGKMCRSSNSMAFLAHIRTHTGSKPFKCKICHFATAQLGDARNHVKRHLGMREYKCHVCGVAFVMKKHLNTHLLGKHGVGTPKERKFTCHLCDRSFTEKWALNNHMKLHTGEKPFKCTWPTCHYSFLTASAMKDHYRTHTGEKSFLCDLCGFAGGTRHALTKHRRQHTGEKPFKCDECNFASTTQSHLTRHKRVHTGEKPYRCPWCDYRSNCAENIRKHILHTGKHEGVKMYNCPKCDYGTNVPVEFRNHLKEQHPDIENPDLAYLHAGIVSKSYECRLKGQGATFVETDSPFTAAALAEEPLVKEKPLRSSRRPAPPPEQVQQVIIFQGYDGEFALDPSVEETAAATLQTLAMAGQVARVVHITEDGQVIATSQSGAHVGSVVPGPILPEQLADGATQVVVVGGSMEGHGMDESLSPGGAVIQQVTKQEILNLSEAGVAPPEASSALDALLCAVTELGEVEGRAGLEEQGRPGAKDVLIQLPGQEVSHVAADPEAPEIQMFPQAQESPAAVEVLTQVVHPSAAMASQERAQVAFKKMVQGVLQFAVCDTAAAGQLVKDGVTQVVVSEEGAVHMVAGEGAQIIMQEAQGEHMDLVESDGEISQIIVTEELVQAMVQESSGGFSEGTTHYILTELPPGVQDEPGLYSHTVLETADSQELLQAGATLGTEAGAPSRAEQLASVVIYTQEGSSAAAAIQSQRESSELQEA
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 407.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXS_STRP4
Sequence: MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMALERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDESEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAVRHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPADAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVGINENEIQILMAERGK
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: RPOB_METEP
Sequence: MANTLVGRKRIRKFFGKIREVAEMPNLIEVQKASYDQFLMVDEPEGGRADEGLQSVFKSVFPISDFASTALLEFVRYTFEQPKYDVDECRQRGITFAAPLKVTLRLIVFDVDPDTGAKSVKDIKEQDVYMGDMPLMTDNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAARIIPYRGSWLDVEFDAKDIVHVRIDRKRKLPVTSLLFALGLDGEEILSTFYNRVAYQRDGADWRVPFDAERLKGFKASVDLIDADSGEVVLEAGKKLNARNARLIGEKGTKFLRAADEDLIGQYIAEDLVNMKTGEIWAEAGDEISEKLLKSLDDVGVTELPVLDIDHVNVGPYIRNTLAVDKNSAREGALFDIYRVMRPGEPPTLDTAEAMFHSLFFDSERYDLSAVGRVKMNMRLDLDAADTVRTLRREDMLAVVKALVDLRDGKGEIDDIDHLGNRRVRSVGELMENQYRLGLLRMERAIKERMSSVDIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIETPFRRVKDGVVTDEVAYLSAMEEAKYYVAQANAGMDEGRKLTDDLVVCRRAGEVIVVAPDRVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRADAPFVGTGMEAVVARDSGAAIAARRSGIVDQVDATRIVIRASEETDPTKPGVDIYRLQKFQRSNQSTCITQKPLVRVGEPVKKGEIIADGPSTEFGELALGRNVLVAFMPWNGYNFEDSILLSERIVKDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVHAGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVPPGVTGTIVEVRVFNRHGVDKDERAQAIEREEIERLAKDRDDEQTILDRNTYARLAEVLIGQSPIAGPKGFRKDTTLTREIISEYPRSQWWQFAVVDDRMMTEIEAMQKQYDESKKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWAAAGLGRKVSKAVDAYLKNQDIAPLRAEMEAIYSPSELEGLSDEALAEAGNNVRRGVPMATPVFNGAKEADIETMLEMAGLDRSAQSTLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELTSSKQQQAANDQIEPPADAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: HSLO_ESCF3
Sequence: MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMSLAVINGNNKQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQIMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEEGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPLF_STAAC
Sequence: MNKNIIIKSIAALTILTSITGVGTTMVEGIQQTAKAENTVKQITNTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVSSDAIIQPGSSGSPILNSKHEAIGVIYAGNKPSGESTRGFAVYFSPEIKKFIADNLDK
What are the official names of this protein?
Serine protease SplF.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_BORPD
Sequence: MSVERTLSIIKPDAVAKNVIGQIIARFENAGLKVIAARLQQLSRADAERFYAVHKERPFFKDLVDFMVSGPVFVQVLEGEGAIQKNRDLMGATDPKKAAPGTIRADFADSIDANAVHGSDAAETAAVEVAFFFPEINIHSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHE9_CRYNJ
Sequence: MACRYPFSPAKVAITRFFYPSPLSRSTTPLFCPPSCRIRVGNTSRMLTSSSSVASEDPKSEMAKFLASPNPKSSASEPGPSPHDVLSAPTSAGHISEAEETLSDQLRNPGSSSSSSPSQSSTNNLSSKNAPFKLSSTYSLPSNISVPPEVREHLIEWSKNVLEHSRYVIQEAQKKFVGLGLKVNEMTGYQEVERLKYMVFEKEDELQRLREHARTAKAAYDEAVAARSEAQRETNILLERKHSWTDADVSKFTSLVRSDHTSSHAVASTSIALKDAEIAVDKSFSQLMQVILQRYHEEQVWSDKIRSVSTWANVAGLAINFIIFVGAVLLVEPWKRKRLVEKLEERVASMMERVDHRLEGVEGHLERVAAGSASASAIKEQHSDAAIQGVEDMPSNSTANPLEFVSPQTIPLMAAVDPTINGSESQSDPFFTQTIRGFPNYLDPLVKPSQKRDLAVAGMAGAVAAWILIGAVRLVRA
What is the function of this protein?
Required for the maintenance of the structure of the mitochondrial inner membrane.  Involved in mitochondrial morphology.  Causes growth arrest when highly overexpressed (By similarity).
What are the official names of this protein?
Sensitive to high expression protein 9 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SHE9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNY_MYCCT
Sequence: MNDDIIILLSVFCGIFFICFIICSSIALYLWKSKSRKRLVEQYTKEAKQAKKQILANGYKEISEAKMLFLKRSELEKNELDRVKEQLELRSNDLKRNQEIVESKSQRLDASLLDLEKRKFLLDKKEEYLIKVLEDASSLTKSQAKELLIKQVKNKSEKELISILKNAELQAHSNSKMIANNIIISAMERIKVELTSQRTTNIVKLPSDDLKGRIIGKDGRNMKAFKQIGGVDIVIDETPNTVVVSSFNPIRREIATRTLEQLIIDGRIQPVKIENELKKQEQELEYIIQETGLSTIKELNINDIDIELVKLIGKLKFRTSYGQNVLAHSIEVAKLSGAIASELGLDVEKAIRAGLLHDIGKAIDFEKQGSHVVLGAEIAKKYNEDPIVINCIESHHEDKEKESEIAAIVAIADSISASRPGARYNAIDEFILRMTEIEKIGNSIPGVAKTYALQSGRQIRLIVDPLVASDLDLAMILEKMKEEIKNKVIIPGEITITVIRERKETDVLK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ALLA_SALEN
Sequence: MKLEVLPLDQKTFSAYGDVIETQERDFFHINNGLVERYHDLAKVEVLEQDRTLISINRAQPAAMPIVVHELERHPLGTQAFVPMNGEAFVVIVALGDDKPELSTLRAFISNGRQGVNYHRNVWHHPLFAWQTVTDFLTVDRGGSDNCDVESIPTHELCFA
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the utilization of allantoin as nitrogen source.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: XAPB_ECOLI
Sequence: MSIAMRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVYSSKGIAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGVLFYAASVTDPDMMFWVMLVNAMAFMPTIALSNSVSYSCLAQAGLDPVTAFPPIRVFGTVGFIVAMWAVSLLHLELSSLQLYIASGASLLLSAYALTLPKIPVAEKKATTSLASKLGLDAFVLFKNPRMAIFFLFAMMLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAYGDPSTTGFILLLLSMIVYGCAFDFFNISGSVFVEQEVDSSIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFSVDGVKDWQTIWLVFAGYALFLAVIFFFGFKYNHDPEKIKHRAVTH
What is the function of this protein?
Uptake of xanthosine (PubMed:11466294).  Can also transport other nucleosides such as inosine, adenosine, cytidine, uridine and thymidine (PubMed:11466294).  Transport is driven by a proton motive force (PubMed:11466294).
What are the official names of this protein?
Xanthosine permease, Xanthosine transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.