PharMolix/UniProtQA huggingface dataset:
Protein: KD5BB_DANRE
Sequence: MTQQGPAEFTPPPECPVFEPSWEEFKDPFAFINKIRPIAEKTGICKVRPPPDWQPPFACDVDRLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWDLQGCTLKIPHVERKILDLYQLNKLVADEGGFDLVCRERRWTKIAMTMGFAPGKAVGSHLRAHYERILYPYNLFQSGTNLLCLQKPGDEVNDIDKEYKPHDLLQRQNVPLQPSNTSAPARRAKRMKTESGCIKSEEGEGVENKPNLRRRMGSFVVKTEPKKEIPIQVKEEPVEIKELNPEPEKSKPKKKNIPPPPVSMVDLYVCLVCGKGNDEDRLLLCDGCDDSYHTFCLIPPLTDVPKGDWRCPKCLTQECCKPQEAFGFEQAHRDYTLKAFGEMADSFKSDYFNMPVHMVPTELVEKEFWRLVGTIQEDVTVEYGADIASKEFGSGFPIKGGRFKIAPHDEKYLQCGWNLNNMAMMTPSVLTHVTADICGMTLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGFAAEQLEAVMKKLAPELFDSQPDLLHQLVTIMNPNTLMAHGVPIYRTNQCAGEFVITFPRSYHSGFNQGFNFAEAVNFCTVDWMPLGRQCVDHYRQLHRYCVFSHDEMVCNMAMKADCLDVVLASAVQKDMQLMIKEERELREKVRKMGVAQCELFQYDLLADDERQCVKCRTTCYLSALTCPCRPGVQVCLYHTHDLCSCPISNYTLNYRFTLDDLYPMMNAVRQRAEYYDDWASRVTEVMEAKLDKKRNVTVFRTLLEESNEQSFPENDLLRQLRLVTQDAEKCSSVAQQLLNGKRQTRYRTGKAKSPNQLTVEEMRSFVRQLYNLPCSLTQAPLLKELLNSIEDFQQHSEKLLSDEVSADAVSEIESLLEEGSQFDVFLPELPLLRERLEQARWLTGVHQAEDPVANPCGLSLESMRRLIDRGVGLTPHPSIERMMARLQELLTVSEELEENAQALLKARPPESLETLCSMLTQVEGVPAYLPNCLLLQDTVNRAKEWLQEAESLQVGGQVPVFSSLSDMVLRAHSIPVRLEPLDQLEVQVSEVQSWKETAAKTFLIKSSPFTLLEVLCPRWEMGSSLKKKKMRKMKGDCVSSGKKKFVKLDSMSDVERALSDSKDSASAMFTLAEVRLKELESLCSLRASNESKLLPTADCASLKVCVCQKPAMGAMLQCELCRDAFHSVCVRGPSDPLDPEAWLCPLCLRSTKPPLDKIRSLLSSLQRIRVRLPEGDALRYMIERSVSWQRRVREVIDSYGLSSTSQDGRGASPSQNLYRSTGHSRKLQLCGSPSRCQDWAVSGQEQTVFYTEQRCIPLQGLSPELEELMVEGLVLQVSLPETQQLYRLLLSGPPTTNTSHAEHKSYLTPPQTETDAITSAEKKAKRRMNRDEVDIRERGTKLKSKKQRMMGVEKRRERKAASVSASDMSQSEDSEEDMTLCPAESCLQPEGEEVDWVQCDCCNRWFHMICVGVSAELAAEEDYMCVSCSTSHMDRRK
What is the function of this protein?
Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'.  Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'.  Acts as a transcriptional corepressor (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 5B-B, Histone demethylase JARID1B-B, Jumonji/ARID domain-containing protein 1B-B, [histone H3]-trimethyl-L-lysine(4) demethylase 5B-B.
What is the protein family that this protein belongs to?
Belongs to the JARID1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS4_JANSC
Sequence: MILYPAIDLKDGNAVRLLRGEMSDATVFNTDPAAQARAFQDAGCDWLHLVDLNGAFAGEPVNGAAVEAILAATSVPTQLGGGIRDMATIEGWLTRGIARVILGTVAVEDPDLVRQAARAFPGQVAVGIDARKGRVATKGWAEETDVMVTDLARAFEDAGVAAIIYTDIDRDGAMGGPNVSATADLARATSIPVIASGGVSSLDDLHALKTTGVISGAISGRALYDGALDLSEALHALA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_ORYSJ
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIWKAIKFEFEPVDKLDS
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2655_BACCR
Sequence: MQPIISFEQFTFQYGHAAQPTLSDITFHIYPGEKVLIAGRSGSGKSTLAHCINGLIPFSYEGNSTGNVLIAGKDPREGSIFEQSKQVGTILQDQDAQFIGLTVEEDVAFYLENECVKQDNMKKIVSDSLRKVKMHTFHKQSPHELSGGQKQTVSLAGLLTTNADILLFDEPLANLDPLSAIHTIELMKDIHEQYNKTIVIIEHRIEEIFKLDLDKVILIDEGKVIAMGTPKEILASNILPRIGLREPIYIEALKRLHFDSNNDVIYPMENLQKEKVSNVIKEWMEKQVILKRNAKNKELLKVENLSFSYPNKQKVLENVNLLIYEGEIVALLGHNGAGKSTLAHSLIGINKMKNGKIALKGEDISSWSIRKRGEIISYVMQNPNHMITQPTVFEEVSFTLTLHNFSKEEIKNKVEGILKICGLYPFRNWPIQALSYGQKKRLTIASVLTTNPKLIILDEPTAGQDYYHYKQFMSFIKNLAKKGISFVVITHDMNLALEYTDRAVVLHEGKIIADNTVFDVLGNQETLQRANLRESSLTKLIKFSGIACPEKFMELYLDSTRREEGA
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein BC_2655.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RBFA_BACC7
Sequence: MKLRANRVGEQMKKELGDIISRKIKDPRVGFVTVTDVQVSGDLQIATVYISVLGDEEQKDSTLKGLAKAKGFIRSEIGQRIRLRKTPEISFEFDESIGYGHRIDTLLHEINKEGKREE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAXX_MOUSE
Sequence: MAPPLLSLPLCILPPGSGSPRLVCYCERDSGGDGDRDDFNLYVTDAAELWSTCFSPDSLARLKARFGLSGAEDIHSRFRAACQQQAVTVSLQEDRALITLSGDTPALAFDLSKVPSPEAAPRLQALTLSLAEHVCNLERRLAAAEETITSPKKNTQPAGTQFLPELDHQRGSSGPGVRRRCPGESLINPGFKSKKPAAGVDFDET
What is the function of this protein?
Non-essential DNA repair protein involved in DNA non-homologous end joining (NHEJ); participates in double-strand break (DSB) repair and V(D)J recombination (PubMed:27601299, PubMed:27798842, PubMed:27601633, PubMed:27830975, PubMed:28051062, PubMed:29077092).  May act as a scaffold required for accumulation of the Ku heterodimer, composed of XRCC5/Ku80 and XRCC6/Ku70, at double-strand break sites and promote the assembly and/or stability of the NHEJ machinery (PubMed:28051062).  Involved in NHEJ by promoting the ligation of blunt-ended DNA ends (By similarity).  Together with NHEJ1/XLF, collaborates with DNA polymerase lambda (POLL) to promote joining of non-cohesive DNA ends (By similarity).  Constitutes a non-essential component of classical NHEJ: has a complementary but distinct function with NHEJ1/XLF in DNA repair (PubMed:27601299, PubMed:27798842, PubMed:27830975, PubMed:28051062).
What are the official names of this protein?
Protein PAXX, Paralog of XRCC4 and XLF.
What is the protein family that this protein belongs to?
Belongs to the XRCC4-XLF family. PAXX subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Predominantly localizes to the nucleus. Accumulates at sites of DNA damage generated by laser microirradiation.
Protein: ACPS_CHLCH
Sequence: MEVGIDIVSLERIEVLYSRYGVRFLEKILLPEEVALCLQKPQIVASVAGRFAAKEAIVKALGSGFAQGVHWKSFAILNDAAGRPYVKVIDDECLPPSSVVKLSISHDRHSAVAVAIIE
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_SALAI
Sequence: MSSLLVDNIGELVTNAGAGDGPLGIRRNAAVLVEDGLVAWVGPNRYPPPADRRIDAEGAAVLPGFVDSHAHLVFAGDRAAEFAARMAGEPYTGGGIRTTVGATRAATDDELRATVRRLRGEALRQGTTTVEIKSGYGLTVPDETRSLRLAAEVSEETTFLGAHLVPAEYADRPDDYVGLVCGPMLAAAAPHARWIDVFCERGAFDADHTRAILTCGQAAGLGARLHANQLGPGPGVQLGVELGAASVDHCTHLTDADVDALAGAGGATVATLLPGAEFSTRSPYPDARRLLDAGVTVALATDCNPGSSYTSSMPFCIALAVREMRMSPTEAVWAATAGGAAALRRTDVGQLTPGARADLMILDAPSHLHLAYRPGVPLIRQVLHNGVPQCRP
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_SHEB2
Sequence: MPADDYPVTELTKALIARPSVTPLDEGCQTLMAERLSAIGFNIEPMVFEDTTNMWARRGNEGPVFCFAGHTDVVPTGDVSRWHTPPFVPTIIDGYLYGRGAADMKGSLAAMVIATERFVAKHPDHNGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWALVGEPSSTLKLGDVVKNGRRGSLTGNLTVKGIQGHVAYPHLADNPIHKAAPFLAELSQMHWDNGNEFFPPTSFQIANINGGTGASNVIPGALDVMFNFRYSTEVTADILIERVETLLKAHELDYDISWIFNGLPFLTGDGPLLDATRIAIRQVTGYETDPQTTGGTSDGRFIAPTGAKVLELGPVNATIHKVNECVKVDDLEQLALCYEVILEQLLC
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: XYND_ASPAC
Sequence: MAVAALALLALLPQALGQHNSSYVDYNVEANPDLFPQCLDTISLSFPDCQSGPLSKNLVCDSTASPYDRAAALVSLFTLEELIANTGNTSPGVPRLGLPPYQVWSEALHGLGRANFTDNGALHAGRPSFPSPILSAAAFNRTLINQIASIISTQGRAFNNAGRFGLDVYSPNINTFRHPVWGRGQETPGEDAYTLTAAYAYEYITGIQGGVNPEHLKLAATAKHFAGYDIENWDNHSRLGNDVNITQQDLAEYYTPQFLVAARDAHVHSFMCSYNAVNGVPSCSNTFFLQTLLRDTFSFVDHGYVSGDCGAVYGVFNPHGYAANEPSAAADAILAGTDIDCGTSYQYHFNESITTGAVARDDIERGFIRLYANLVELGYFDGNSSSSNPYRSLGWPDVQKTDAWNISYEAAVEGIVLLKNDGTLPLASPSEGKNKSIALIGPWANATTQLQGNYYGDAPYLISPVDAFTAAGYTVHYAPGTEISTNSTANFSAALSAARAADTIVFLGGIDNTIEAEAQDRSSIAWPGNQLELISQLAAQKSDDQPLVVYQMGGGQVDSSSLKFNAKVNALLWGGYPGQSGGLALRDILTGARAPAGRLTTTQYPAAYAESFSALDMNLRPNETTQNPGQTYMWYTGEPVYAFGHGLFYTTFNASSAQAAKTKYTFNITDLTSAAHPDTTTVGQRTLFNFTASITNSGQRDSDYTALVYANTSTAGPSPYPNKWLVGFDRLAAVAKEGGTAELNVPVAVDRLARVDEAGNTVLFPGRYEVALNNEREVVVEVELVGEQVVLLKWPEEVQGVAGDE
What is the function of this protein?
Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable exo-1,4-beta-xylosidase xlnD, 1,4-beta-D-xylan xylohydrolase xlnD, Beta-xylosidase A, Beta-xylosidase xlnD, Xylobiase xlnD.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTU_META1
Sequence: MAKLDFDRSKPHVNIGTIGHVDHGKTTLTAAIATVLSKKGLSEARDYASIDNAPEEKARGITINTSHIEYNSEKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLAKQVGVPKIVVFLNKIDMFKDDEREEMVGLVEMDVRGLLSEYGFDGDNAPVIAGSALKALQGDPKYEDIIMELVQAVDDYIDEPKRETDKPFLMAIEDVFTITGRGTVATGRVERGVLQLNEEVEIVGIKPTKKTVVTGIEMFRKNLKQAQAGDNAGLLLRGVERTEIERGQVLAKPKTIIPHTEFEATVYVLKKEEGGRHTPFFQNYKPQFYFRTTDVTGGIKFQDGREMVMPGDNVQFTVTLISPIAVEEGTKFSIREGGRTVGAGSVTKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLB76_CHITH
Sequence: MKFFAVLALCIVGAIASPLTADEASLVQSSWKAVSHNEVEILAAVFAAYPDIQNKFSQFAGKDLASIKDTGAFATHATRIVSFLSEVIALSGNDSNAAAVNSLVSKLGDDHKARGVSAAQFGEFRTALVAYLQANVSWGDNVAAAWNKALDNTFAIVVPRL
What are the official names of this protein?
Globin CTT-VIIB-6.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SUBT_BACSU
Sequence: MRSKKLWISLLFALTLIFTMAFSNMSAQAAGKSSTEKKYIVGFKQTMSAMSSAKKKDVISEKGGKVQKQFKYVNAAAATLDEKAVKELKKDPSVAYVEEDHIAHEYAQSVPYGISQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLNVRGGASFVPSETNPYQDGSSHGTHVAGTIAALNNSIGVLGVAPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPTGSTALKTVVDKAVSSGIVVAAAAGNEGSSGSTSTVGYPAKYPSTIAVGAVNSSNQRASFSSAGSELDVMAPGVSIQSTLPGGTYGAYNGTSMATPHVAGAAALILSKHPTWTNAQVRDRLESTATYLGNSFYYGKGLINVQAAAQ
What is the function of this protein?
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.
What are the official names of this protein?
Subtilisin E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_GEOSM
Sequence: MANHKSAMKRIKQTAKRTERNKHERSTLRTFIKRVREAVATKDQEAAKAALAVAIPVIDGAATKGIIHSSNASRNVSRLTKLVNTLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: DNSL3_MOUSE
Sequence: MSLHPASPRLASLLLFILALHDTLALRLCSFNVRSFGASKKENHEAMDIIVKIIKRCDLILLMEIKDSSNNICPMLMEKLNGNSRRSTTYNYVISSRLGRNTYKEQYAFVYKEKLVSVKTKYHYHDYQDGDTDVFSREPFVVWFHSPFTAVKDFVIVPLHTTPETSVKEIDELVDVYTDVRSQWKTENFIFMGDFNAGCSYVPKKAWQNIRLRTDPKFVWLIGDQEDTTVKKSTSCAYDRIVLCGQEIVNSVVPRSSGVFDFQKAYDLSEEEALDVSDHFPVEFKLQSSRAFTNNRKSVSLKKRKKGNRS
What is the function of this protein?
Has DNA hydrolytic activity.  Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends (By similarity).  Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA (PubMed:15796714, PubMed:19154352, PubMed:12095301).  Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis.  The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells (PubMed:12050166, PubMed:15167901, PubMed:17218958, PubMed:24312463).  Is active on chromatin in apoptotic cell-derived membrane-coated microparticles and thus suppresses anti-DNA autoimmunity (PubMed:15796714, PubMed:27293190).  Together with DNASE1, plays a key role in degrading neutrophil extracellular traps (NETs) (PubMed:29191910).  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (PubMed:29191910).  Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation (PubMed:29191910).
What are the official names of this protein?
Deoxyribonuclease gamma, DNase gamma, DNase I homolog protein DHP2, Deoxyribonuclease I-like 3, DNase I-like 3, Liver and spleen DNase, LS-DNase, LSD.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum. Secreted. Note=Contradictory reports exist about the subcellular localization under normal physiological conditions. Shown to translocate to rough endoplasmic reticulum and to be transported through the entire secretory pathway for secretion. However, under conditions of cell death, may diffuse and/or be actively transported to the nucleus.
Protein: NQRD_SHEPA
Sequence: MADAKELKQVLIGPIVSNNPIALQILGVCSALAVTSKMETALVMTIALTAVCALSNLFISLIRNHIPSSVRIIVQMTIIASLVIVVDQVLQAYAYDVAKQLSVFVGLIITNCIVMGRAEAYAMKTPPMMSFMDGIGNGLGYGAILLSVGFVRELFGNGSLFGIEILSKISDGGWYQPNGLLLLPPSAFFLIGALIWIIRVMKPEQVEAKG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ILVD1_METAC
Sequence: MRSAIIKEGPERAANRSLLKATGVTDSEMKKPFIAVVNSWNEIVPGHIHLDKLAEAVKAGIRNAGGVPFEFHTIGVCDGLAMGHEGMKYSLPSREVIEDTIELMVRAHQFDGMVLIPTCDKIVPGHLMAAGRLDIPAIVVTGGPMLPGYVDDKYTDLISVFEGVGAYSAGKLSEAELKRLENLSCAGAGSCAGMFTANTMACMTEALGLSLPGCATAHAVDAKKVRIAKESGERIVALVKENLTPRKIVTQKSFENAIMVDMAVGGSTNTTLHLPALAHEFGLELPLKTFDELSRTTPHLISLRPGGPNFMLHFDRAGGVEAVVQRLASKLHLDQLTVNGKTIGENLDELEIVNPKLNAEIITTLENPIHAEGGIAVLKGSLAPDGSVVKQAAVDPKMRVHTGPAKVYDCEEDAMKSILAGDVKPGDIVVIRYEGPKGGPGMREMLAATAAIGGMGLLESVALITDGRFSGGTRGPCIGHVSPEASEGGPIGLVKDGDLIEINIPERILNLKVTEEELEKRKAAFVPPKKEVTGYLARYQRSVHSANTGGIVD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 1, DAD 1.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PTER_XENLA
Sequence: MSSLSGKVQTVLGPIHSDQLGHTLTHEHLSMTFECCYCPPPAPQGALSDAPILMKNLFWVKQNPYSNKENLLLNQEIDAISEELKLFKAAGGGSIVENTTTGISRDVKMLKKLAEETGVNIISGAGFYVDATHSNSTRSMTVEQLTEVLVNEVLQGADGTNIKCGIIGEIGCSWPLTESEKKVLQATAEAQSQLGCPVNIHPGRNSDAPFQIIQILQEAGADISKTVMSHLDRTIFDETKLLEFAKLGSYLEYDLFGTEMLNYQFNQAVDMPSDNDRIKMLRFLINEGYEDRIVVSHDIHTKNRLLKYGGHGYSHILNNIVPKMLIRGISQQCIDKILLENPKKWLTFK
What are the official names of this protein?
Phosphotriesterase-related protein, Parathion hydrolase-related protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
Protein: NQRE_VIBVU
Sequence: MEHYISLLIKSIFIENMALSFFLGMCTFLAVSKKVKTSFGLGVAVVVVLTIAVPVNNLVYNLVLKENALVEGVDLSFLNFITFIGVIAALVQILEMILDRFFPPLYNALGIFLPLITVNCAIFGGVSFMVQRDYNFAESVVYGFGAGVGWMLAIVALAGIREKMKYSDVPPGLRGLGITFITVGLMALGFMSFSGVQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLHD_RALP1
Sequence: MEATSLLSEIRSLNIAYLRLARRLLATDQALATTALGISQSMGEALLTLDEEACVRMAQTNLFLCRIHFDDRVLAALLAGPRLELLESPASAGKAAPAIA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_STRT2
Sequence: MISSLHRPTLAKVDLSAISENIEQVVSHIPKQVQTFAVVKANAYGHGAVEVAKHVSKQVDGFCVSNLDEALELRQAGIEQPILILGVVLPDGVPLAIQENISLTVASLEWLTLAQKQGLDLTGLTCHIKVDSGMGRIGVRNLKDADNLIAGLKALGADVEGIFTHFATADEADDSKFKRQLSFFTDLVDNLTDRPRLVHASNSATSIWHAATVFNTVRLGVVIYGLNPSGSVLELPYNIQPALSLETALIHVKTLPAGQDVGYGATYTTTDEEVIGTLPIGYADGWTRDLQGFHVIVDGQLCPIVGRVSMDQITVRLPKVYPLGTPVTLMGENGGVSITATEVAEKRGTINYEVLCLLSDRVPRSYD
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: LAP_BOVIN
Sequence: MRLHHLLLALLFLVLSAGSGFTQGVRNSQSCRRNKGICVPIRCPGSMRQIGTCLGAQVKCCRRK
What is the function of this protein?
Shows a broad spectrum of antibacterial and antifungal activities.
What are the official names of this protein?
Lingual antimicrobial peptide.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family. LAP/TAP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NFSA_ECOLI
Sequence: MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWPADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR
What is the function of this protein?
Catalyzes the reduction of nitroaromatic compounds using NADPH.  Has a broad electron acceptor specificity.  Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product.  Major oxygen-insensitive nitroreductase in E. coli.
What are the official names of this protein?
Oxygen-insensitive NADPH nitroreductase, Modulator of drug activity A.
What is the protein family that this protein belongs to?
Belongs to the flavin oxidoreductase frp family.
Protein: IF3_SHEWM
Sequence: MKIKKTAGRQAAPNRINELITGISEVRLNGLDGEPLGLMTIREAQELADEAGVDLVEISPNAEPPVCRIMDYGKFLFDKAKSQKEQKKKQKIVQVKEIKFRPGTDENDYQVKLRNLNRFLDDGDKAKVTLRFRGREMAHQSLGMNLLNRIKDDLAEIAVVESFPKMEGRQAVMVLAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_SHESW
Sequence: MQLNSTEISDLIKQRIEQFEVVSESRNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYADLAEGVKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPIDNDGFSPVEVIAPGVIERQSVSQPVQTGYKAVDAMIPIGRGQRELIIGDRQTGKTAMAIDAIINQKDSGIKCVYVAIGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQFLAPYSGCSMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNEIYVEKFTKGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFSQFASDLDDATRAQLEHGVRVTELMKQKQYAPMSVAAQSVSIFAAEKGYLKSVELKKVGDFEAALLSFMNSEHAALMKLINETGDYNAEIEAELKAGLDKFVATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.