PharMolix/UniProtQA huggingface dataset:
Protein: YIHD_ECOLI
Sequence: MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELADLTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE
What are the official names of this protein?
Protein YihD.
What is the protein family that this protein belongs to?
To H.influenzae HI_0845.
Protein: SUV91_XENLA
Sequence: MAENSNGALGCVVRCLSSESELQELCREEQLCCAELGVTRKNLSDFEVEYLWNYKKVQDQELYLVKWKYYPDSESTWEPRHHLKCNNLLKQFHLDLERELLRRAKAAGTKKTAVRCPRRLDQSLSHYLVLKAKQRKRLRQWAQQLNAKRSHLGLILVENEVDLEGPPRDFVYINEYRVGEGVTINRISAGCKCRDCFSDEGGCCPGAFQHKKAYNNEGQVKVKPGFPIYECNSCCRCGPSCPNRVVQKGIQYKFCIFRTSDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGTTYLFDLDYVEDVYTVDAARYGNISHFVNHSCKPNLQVYNVFIDNLDERLPRIAFFATRTIRTGEELTFDYNMQVDPVDVESSKMDSNFGIAGLPASPKKRVRVECKCGVSSCRKYLF
What is the function of this protein?
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate.  H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones.  Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions.  H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.  SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes (By similarity).
What are the official names of this protein?
Histone-lysine N-methyltransferase SUV39H1, Suppressor of variegation 3-9 homolog 1, Su(var)3-9 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associates with centromeric constitutive heterochromatin.
Protein: STUA_TALMA
Sequence: MNQTQSYMDVHTSHFSSPQPYGSHGATAGGMVPYSHYQQPPPLLPPGSAGYPSTPGSYSYPYSNGVASTTQPASNSISSQVPAQILPLPAMTSHTVTPHGYVSGAAQSQQNAVHDPTGQTCPPGAKPRVTATLWEDEGSLCYQVEAKGVCVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPYERALDFANKEKITDLLYPLFVHNIGGLLYHPANSNRTNMVVHDSQQRRLEGSQTARTSQGPQAPALHHHHSMNGSVPSHMPQASASTPQTNGRPELNRAHTFPTPPASASSLIGIPNQGSTYDWNSQNINSTVQTSQNVPIDNGLNSTRSMPTTPATTPPGNNLQGMPPYQNQPAYDSSKSYYSAAPSSQAQYASQPLPAHSLTYGQPMMKDLGSSGRPPLGPVEQEHDEVKVDRYNQPNGQVTNGTEEENGQQQEPEYVQDNVAGSYANRNSYTYTTNPSVSSLSGDHSQLGGSPSHQNGSDRMTPRTAGTNPPPQWSQGYNTPPRAVPAGSISNIVSDTRGAPNGDSYAPGTAYASNYSGYSSVNGSSMGSTKRMRDDDDDHLSRSDGRENEYETKRRKTLTEPPVGGAFMQMQQQPVPAGGVMRRR
What is the function of this protein?
Transcription factor that regulates asexual reproduction (PubMed:11994146, PubMed:20465521).  Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).  Required for accurate spatial organization of the developing conidiophore (PubMed:11994146, PubMed:20465521).  Primarily involved in the formation of the uninucleate sterigmata, which arise by budding in this multicellular structure (PubMed:11994146).  Required for metula and phialide formation during conidiation but is not required for dimorphic growth (PubMed:11994146).
What are the official names of this protein?
Cell pattern formation-associated protein stuA, Stunted protein A.
What is the protein family that this protein belongs to?
Belongs to the EFG1/PHD1/stuA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARND_ECOLI
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIEAKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVVRGNIAGREGWLGCQQIAGSR
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (Probable).
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: SYFB_MAGSA
Sequence: MKFTLDWLKSHLDTDATLEQIEVGLTAIGLEVEGIDDPSKHLGGFVVGHILEAEKHPDADKLKLCKVDSGAGILQVVCGAPNARAGLKVILAQPGTYIPITGDVLKKGKVRGVESQGMMCSWRELKLGEDHDGIAELDVTLAVGASLLDIMSFDPMIEISVTPNRVDCLGVRGIARDLAAFGLGNLKPLKVEPVPGAFKSSIGVRLEFAPEDSNACPLFAGRLIRGVKNGDSPQWLKDRLTAIGLRPISALVDITNFFAYDLCRPLHVFDAAKVKGDIRARLARDGETLAGLNGKTYTLESGMTVIADENGPEALAGILGGEHSGCTEATTEVFLEAAYFDPIRTAATGRKLDILSDARFRFERGVDPAFVVPSMELATRMILDLCGGEASEAVIAGTEPDWQKSIVLRPNRVAELGGVEVSTQRMETILNDLGCAVAEHADGLLVNPPSWRGDITAEHDLVEEVIRINGYDNIPATPMPRPAMPKPVLTPGQRRSGWVRRQLATRGLVETVTWSFLPEAQAVMFGGGAPEMHLANPISSDLDVMRPSVLPNLVTAAGRNADRGMKDLGLFELGPQFDGPEPGQQRLVAAGIRAGRARGRHWADPARAVDAFDAKADILSAVAAAGANPDSLQVVAEAPVWYHPGRSGTLKLGNKPVGFFGEIHPGLLAKLDVKGPVAGFELFLEALPAQKAKATKAKPLLKASALQPLDRDFAFTLDTGVAADAVVRAARNADKVLISDVAVFDLYEGDKMAAGKKSLAITVTLQPTDKTLTDEDIEAVGAKIVAAVAKATGGELRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_SHIF8
Sequence: MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTSVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSSRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRAGQQQQRLTQRLNQQNPQPKIHRTQTRIQQLEYRLAEILRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKKSRKKVH
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_SYNP6
Sequence: MAHPIPVVVNGATGKMGRETIKAIAAADDVTLVGAIARSADVQGQDIGEIVGLGPLEVPVTNDLEGMLCLASQEREVPVVVDFTHPDCIYDNVRKAIAYGVRPVVGTTGLNNEQLQELAEFAEKASVGCLVIPNFSIGMVLLMQAAIQASRFYDHVEILELHHDQKADAPSGTAIKTAQMLAELGKTFNPPKVTEKETMPGARGAVGPENIRIHSVRLPGLIAHEEVIFGAPGEILTLRHDTMDRSCYMPGVLLAVRKVRQLTGLIYGLDRIP
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_ACIC5
Sequence: MTVNGWLQIGIFIAAVLLGAKPLGVYMAAVFERRHTWLDPVLVPVEKLLYRLTAVKAEEEMHWTAYCASMLIFSAATMLLTYLIERVQQFLPLNPQHLGGVPAQLAWNTAISFTTNTNWQAYTPESTMSYLTQMVGLATHNFWSAAVGIALAIAFIRGIARKEMKTLGNFWVDMTRAILWVLLPICVVFALVLTSQGVIQNLKSYTVAHVVQPQSQTQTVNGKTVTTTDSTQTIAQGPVASQEAIKMLGTNGGGFFNANSSHPFENPTPLSNMLEMISIFLIPAGLTVTLGQMTGSPRHGWAVLGAMLILWFAGVATCYWAEAQPNPLFHGVNQQATALQAGGNMEGKEVRFGIADSALFATVTTDASCGAVNAMHDSFMPLGGMVPLTNIMLGEIVFGGVGAGLYGMLVFVIVAVFIAGLMVGRTPEYLGNKIQAYDVQMAMLYLLIFPLIILGFSAVAVLTPHLGLPSISNPGPHGLTQILYAYSSATGNNGSAFAGLNANTSWYNLSLGFAMFIGRFLMIVPMLALAGNLAQKKNVPETLGTFPVTTPLFTVLLTSVIIVVGALTFLPALSLGPILEHLLLQAGRTF
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS9_THEPX
Sequence: MATVQYYGTGRRKEAVARVRLMPGKGNIIINNRPLEEYFTLDTLKYTVKQPLILTETIDKFDVYAKVSGGGLTGQAGAVRLGIARALVKVDSELRPILKKAGFLTRDPRMKERRKYGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: SKP1_TALMQ
Sequence: MSGQVTLQSSDSVDITVERAVAERSMLIKNLLEDLGESEEPVPIPNVNESVLKKVIEWCTHHKNDPQSTGEDDDNRRRTTEIDEWDQKFMQVDQEMLFEIILAANYLDIKALLDVGCKTVANMIKGKSPEEIRKTFNIQNDFTPEEEDQIRRENEWAEDR
What is the function of this protein?
Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor (By similarity).
What are the official names of this protein?
E3 ubiquitin ligase complex SCF subunit sconC, Sulfur controller C, Sulfur metabolite repression control protein C.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
Protein: TX41F_ETHRU
Sequence: LLVCLFVCWNAVGAQDARSAFSSEETAQDQHVMEERIFINPCRKPGKNACMENCRSSPNCKTMSFVQSSIRP
What are the official names of this protein?
U-scoloptoxin(04)-Er1f, U-SLPTX(04)-Er1f, U-scoloptoxin-Er1.1a2e, U-SLPTX-Er1.1a2e.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-04 family.
What are the subcellular locations of this protein?
Secreted. Note=The mature toxins are clearly liberated from the multidomain precursors in the venom gland prior to venom expulsion and not by venom proteases upon secretion.
Protein: MUL1_HUMAN
Sequence: MESGGRPSLCQFILLGTTSVVTAALYSVYRQKARVSQELKGAKKVHLGEDLKSILSEAPGKCVPYAVIEGAVRSVKETLNSQFVENCKGVIQRLTLQEHKMVWNRTTHLWNDCSKIIHQRTNTVPFDLVPHEDGVDVAVRVLKPLDSVDLGLETVYEKFHPSIQSFTDVIGHYISGERPKGIQETEEMLKVGATLTGVGELVLDNNSVRLQPPKQGMQYYLSSQDFDSLLQRQESSVRLWKVLALVFGFATCATLFFILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSFKSCVFLECGHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS
What is the function of this protein?
Exhibits weak E3 ubiquitin-protein ligase activity (PubMed:18591963, PubMed:19407830, PubMed:22410793).  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates (PubMed:18591963, PubMed:19407830, PubMed:22410793).  Can ubiquitinate AKT1 preferentially at 'Lys-284' involving 'Lys-48'-linked polyubiquitination and seems to be involved in regulation of Akt signaling by targeting phosphorylated Akt to proteosomal degradation (PubMed:22410793).  Mediates polyubiquitination of cytoplasmic TP53 at 'Lys-24' which targets TP53 for proteasomal degradation, thus reducing TP53 levels in the cytoplasm and mitochondrion (PubMed:21597459).  Proposed to preferentially act as a SUMO E3 ligase at physiological concentrations (PubMed:19407830).  Plays a role in the control of mitochondrial morphology by promoting mitochondrial fragmentation, and influences mitochondrial localization (PubMed:19407830, PubMed:18207745, PubMed:18213395).  Likely to promote mitochondrial fission through negatively regulating the mitochondrial fusion proteins MFN1 and MFN2, acting in a pathway that is parallel to the PRKN/PINK1 regulatory pathway (PubMed:24898855).  May also be involved in the sumoylation of the membrane fission protein DNM1L (PubMed:18207745, PubMed:19407830).  Inhibits cell growth (PubMed:18591963, PubMed:22410793).  When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis (PubMed:23399697).  Involved in the modulation of innate immune defense against viruses by inhibiting RIGI-dependent antiviral response (PubMed:23399697).  Can mediate RIGI sumoylation and disrupt its polyubiquitination (PubMed:23399697).
What are the official names of this protein?
Mitochondrial ubiquitin ligase activator of NFKB 1, E3 SUMO-protein ligase MUL1, E3 ubiquitin-protein ligase MUL1, Growth inhibition and death E3 ligase, Mitochondrial-anchored protein ligase, Protein Hades, Putative NF-kappa-B-activating protein 266, RING finger protein 218, RING-type E3 ubiquitin transferase NFKB 1.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Peroxisome. Note=Transported in mitochondrion- derived vesicles from the mitochondrion to the peroxisome.
Protein: RS10_SHEHH
Sequence: MQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTILTSPHVNKDARDQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MURE_DEIRA
Sequence: MRLSDLAAALQLPAPETDPQTDTEVTGVTHNAAWVQPGSAFVAIRGAKFDGHSFMEQAQAAGAVAVLGEGLADGQTSPLPYLTVPNARAALADAAAALAGHPSRELKVVGVTGTDGKTTTSWLTRHLLRSAGLATGLLSTVGYELPDGELRHFPAHFTTPEAPQVQDTLREMVAAGAQATVLEASSHALSLDRVRGVDWDVAVWTHLSSEHLDFHGTLDNYFADKRKLVERARFAVLNVDDPWTAQLRGIAPGETTYSAENQHADWRAQDIEERHSGLHFRVVSPAGDFQAELPMIGRFNVANALAGMAAAHHLGATALQLQAGLASFRGVPGRMELVPGGATSPRVIVDFAHTPPSLEKALGTLRATTAGHLWVVIGSAGGPRDPYKRAPLGEVATRLADHAILTEEDCRDTPLQDILNEMERGAREEGRSNFVSIGDRREAIRYAVTHAQPGDTVLLAGKGPEDTLERATETLPWNEVAEARAVLAER
What is the function of this protein?
Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramyl-tripeptide synthetase, UDP-MurNAc-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PROM1
Sequence: MTIKLESLQSNKGSRRKKMRKGRGIAAGQGASCGFGMRGQKSRSGRPTRPGFEGGQMPLYRRVPKLKHFPIVNQKNFTVLNVSRLNALKDGTIVNLDLLVKEGILTKPKNPLKILGNGNLEVKLTVQAAAFTASAKKKIEEVGGSCELYN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SYE_SYNJB
Sequence: MSVCVRIAPSPTGNLHIGTARTAVFNWLYARRHGGRFILRIEDTDRDRSLPRYTRNILAGLAWLGLDWDEGPVYQSKRIERYQAVVQQLLDRGLAYRCYVSEAELEEMRAAQKAAGKAPRYDNRHRFLTEAQRRAYEAEGRQPVIRFKIEEPLEVSWVDLIRGPITWNTQDLGGDMVIARADGCPLYNLAVVVDDIDMGITHVIRGEDHIGNTPKQILLYRALGHEPPQFAHSPLILNPEGKKLSKRDGATSVAEFQQLGFLPEALKNYLALLSWSPPDGEELFSLEKAAALFDFDRVNRAAARFDWDKLNWINSQYIKRLSPPELVERLTPFWQAAGFDLSEVPDPTWLEDVARLIADGIDRLAEAPPLSRFLFQEPLSYTLPALEQLRLPGVAEAMAAMATTLAAAELPQVSADSLKPLVDQVAKGQNMKKGLLMKSLRAALTGDLQGPDLLESFALLQRRGWALGRLEAVQKLVPC
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1162_METJA
Sequence: MVKYMKIVGITDLHGKLPPAVREFKDFADVLVVCGDITHFGKGIEVIEKLAELSDYMEVLCVPGNCDTKEVIDELNSFKLNIDRKVKKIENINFVGIGGSNKTPFNTPNEYTEEEIYNKLINVVKNLKNIFLVSHAPPYNTMADIVDLDKDIHVGSKSIRKIIEDFNENIRFCACGHIHESRCIDKIGNTIVVNPSPKSYFVYDTKKNMVVLDDFNGF
What are the official names of this protein?
Uncharacterized protein MJ1162.
Protein: SYI_BORAP
Sequence: MFKKVENKANFPKIEEKILKFWNDNKIFEKSMKQREGCEEFTFYDGPPFATGLPHFGHFVPNTIKDIIPRYQTMRGKYVKRNFGWDTHGLPVEYEVEKKLGISGKYEIENYGIENFNKECKKIVLRYTEEWKNIILRLGRWVDFEKGYKTMDINFMESVWWVFKSLYNKGLIYESYYVLPYSPKLATPLSNFEVNLGEYKEVNDPSLTIKFKIKDKNEYLLAWTTTPWTLPSNLGIAVGQEIEYSKIFDKKKEEILILGSKKLDSYYDDENSYTIIEKFKGSKLEGIEYEPIFNYFLEQKDKGAFKVHMADYVTTDDGTGIVHIAPFGEEDYRILKKHTNVDIIDPLDAECKFTNRVKDFQGLFVKDADKKIIENLKLRNFLFKRENYLHRYPFCYRTNYPIIYRPISSWFVNVEKIKTKLLEVNEKINWMPAHLKKGRFGKWLENAKDWAISRNRFWGNPIPIWICSKTGKKICVGSKKELESLSGQKIEDLHKDKVDKITWPSKDGGTFIRTSEVLDCWFESGAMPYASNHYPFTNESNFKNIFPADFIAEGLDQTRGWFYTLTILGVSLFESTAFKNVIVNGLVLSSDGRKMSKSFKNYTDPMEVINTFGADALRLYLIMSPVVKADDLKYSDNGVRDVLKNIIIPIWNAYSFFTTYAIIDKFQPPKNLNLVKNNNLDKWIISELESLKKILNNEIDKYNLTKSIESLLEFIDKLNNWYIRRSRRRFWKSENDKDKNDAYETLYYAIKTLMILLAPFIPFITEEIYQNLKTDEDKQSIHLNDYPKANENLINKTIEEKINLARKITSMARSLRSLHNIKIRMPISMIYIVTKNQNEQNMLIEMQEIILDEINAKEMKIKSNEEDLITYKAKANFKELGKKLGKDMKTVSIEISKLKNEDIIKIINGISYEIKVGNTKYYLSLNDIILEREEKDNLKVINEESITIGIDSLITKELYLEGLTREFVRQIQNLRKEKNFDVSDRINLYIENNETLQEILNKFEKYIKTETLALNIIFNKSKLEKKINLDDNIFTIIGIEKC
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BADM_RHOPA
Sequence: MPMRLQKSTMCGLYAVLELAANPDRQVSAGDIADKYDISLNHLAKVLRALVRARLIESVRGPGGGYRFAGNPKRVTLLDIIALFEDTGLDLQEAASDDHEESRALHKVLRDIDEIAMTTLRSVSITSLLKVIDTERRKTERGPNGASARHSSAGRA
What are the official names of this protein?
Putative HTH-type transcriptional regulator BadM.
Protein: SYT15_HUMAN
Sequence: MAEQLALVIGGTIGGLLLLLLIGASCCLWRRFCATLTYEELPGTPAMATTAASSGQRDRPCQPHARTQLSRPPAVPFVVPPTLQGRDWVPLHSGEWADAPWDPCPASELLPHTSSGGLGDACMVGAINPELYKFPEDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETCSPLVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHALCRTTEP
What is the function of this protein?
May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues.
What are the official names of this protein?
Synaptotagmin-15, Chr10Syt, Synaptotagmin XV, SytXV.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type III membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane; Single- pass type III membrane protein. SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane; Single- pass type III membrane protein.
Protein: CCME1_XANCP
Sequence: MNATRKQRLWLVIGVLTAAALAVTLIALALQRNMSYLFTPSQVDAGAAAGYQQFRLGGMVKAGSIQRATDSLTVTFKVIDKHAATQVEYTGILPDLFRDNQSVIANGRMQAGRFVANEVLAKHDETYMPKELKDAMAEGHVGKPIPAAAAPLSGVR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE 1, Cytochrome c maturation protein E 1, Heme chaperone CcmE 1.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RISB_ACIET
Sequence: MFGADKGTADKLDGKKLHIGIVQARFNENITNTLAAACRAELLRLGVQEKHIRHVLVPGALEVPVALQALAERDEYDALIALGCIIRGETYHFELVANESGAGVTRLALDYQVPIANAIITTENLDQALARQTEKGVDAARVAVEMANLLEELS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: POTA_MANSM
Sequence: MENIVQSKPIIELRSLKKSYNENTIIDNFNLTINNGEFLTILGPSGCGKTTVLRLIAGFEEANGGQIILDGEDVTDLPAEHRPVNTVFQSYALFPHMTIFENVAFGLRMQKVPNEEIKPRVLEALRMVQLEEMADRKPTQLSGGQQQRIAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFIFVTHDQEEALTMSDRIIVLRKGNIEQDGSPREIYEEPSNLFVAKFIGEINIFDAQVLNRVDEKRVRANVEGRVCDIYTDLAVKEGQKLKVLLRPEDVQLEELDENEQSSAIIGHIRERNYKGMTLESTVELEHNNKLVLVSEFFNEDDPNIDHSLDQRVGVTWIEKWEVVLNDENDNA
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NRDR_PEDPA
Sequence: MKCPHCGNNGSRVVDSRPTDEGRVIRRRRECEKCGFRFTTFERVEATPLLVIKKNGSREEFDRDKILKGIVRAAEKRPLNMEQMTDMVDKVENKVRSLGESEISSQIIGEYVMNILVDLDEIAYIRFASVYRQFKDMHVFLDELQDMMKKDEEKEKE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PYRC_JANSC
Sequence: MTQSLTIRRPDDWHLHLRDGAMMRAVLPETARHFARAIIMPNLVPPVVTAQDALAYRDRIEAALPDGADFTPLMTLYLTEQTDPDDVEAAFADGLIHAVKLYPAGATTNSQSGVATLKNVYPVLERMAQIGLPLCIHGEVTDPQVDIFDREQAFIDTVLIPLRADLPDLKVTLEHITTSHGIDYVVGADGDIAGTITTHHLMINRNHMLVGGIRPHYYCLPIVKRASHQHALRRAATSGHPRFFLGTDSAPHLDGAKETACGCAGVFSATNTMSCLAHVFDEDGALVNLEAFTSLNGPARYGLAPNAATMTLEKRDHPTNYPAKFDTDDGPLTLFDPSTPLYWHVKD
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: SSB_BIFLO
Sequence: MAGETVITIVGNLTADPELRTIGSGVTVASFTIASTPRTWNRQTNQFEDGQALFMRCSAWRDLADHCAQSLKKGMRVIATGRLQQRSYQAQDGSQRTVVEMQLDEIGPSLRYATAQVTRQSSGQGGFQGRSGGFQGGQQPNQGYGNQGGQGGYAGGQGGYNGGYQGGGAGYSQQSAAPANPSAPAVDPWSNAGASDAGSFSTFGASSDFGGDDSDPEF
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: GLPE_PSEF5
Sequence: MSEFKRIPPEQAQALREQGAVVVDIRDPQTYALNHISGSQHLDNHSISDFIRAADLDAPLVVVCYHGNSSQSAAAYLVSQGFSDVYSLDGGFELWRSTYPAETAQGNPE
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.