PharMolix/UniProtQA huggingface dataset:
Protein: EPC1_MOUSE
Sequence: MSKLSFRARALDASKPLPVFRCEDLPDLHEYASINRAVPQMPTGMEKEEESEHHLQRAISAQQVYGEKRDNMVIPVPEAESNIAYYESIYPGEFRMPKQLIHIQPFSLDAEQPDYDLDSEDEVFVNKLKKKMDICPLQFEEMIDRLEKGSGQQPVSLQEAKLLLKEDDELIREVYEYWIKKRKTCRGSSLIPLVKQEKRDGSSTNDPYVAFRRRTEKMQTRKNRKNDEASYEKMLKLRRDLSRAVTILEMIKRREKSKRELLHLTLEIMEKRYNLGDYSGEIMSEVMAQRQPVKPTYAIPIIPITNSSQFKHQDATDSKEFKVNKQDKADLIRPKRKYEKKPKVLPPSAAAPQQQSPAALPGFSAKDLNQYDFPSSDEEPLSQVLSGSSEAEEENDPDGPFAFRRKAGCQYYAPHLDQTGNWPWTSPKDGGLGDVRYRYCLTTLTVPQRCLGFARRRVGRGGRVVLDRAHSDYDSMFHHLDLDMLSSPQPSPVNQFANTSEPNTSDRSSSKDLSQILVDIKSCRWRHFRPRTPSLPDSDSGELSSRKLHRSISRAGAAQPGAHTCSTSTQNRSSSGSAHCAFTAEQYQQHQQQLALMQQQQLAQTQQQQQANSSSSAAAQQGFVSKTLDSASAQFAASALMTSEQLLGFKVKDDVVLGLGVNGVLPASGVYKGLHLSSTTPTALVHTSPSTAGSTLLQPSNITQTSGSHSSLSHQVTAASSATTQVLFGNNIRLTVPSSVPTVNSVTPINARHIPRTLSAVPPSALKLAAAANCQVSKVPSSSSVDSVPRENHESEKPALNNIADNTVAMEVT
What is the function of this protein?
Component of the NuA4 histone acetyltransferase (HAT) complex, a multiprotein complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A (PubMed:28694333).  The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) by promoting homologous recombination (HR) (By similarity).  The NuA4 complex is also required for spermatid development by promoting acetylation of histones: histone acetylation is required for histone replacement during the transition from round to elongating spermatids (PubMed:28694333).  In the NuA4 complex, EPC1 is required to recruit MBTD1 into the complex (By similarity).
What are the official names of this protein?
Enhancer of polycomb homolog 1.
What is the protein family that this protein belongs to?
Belongs to the enhancer of polycomb family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: KBAY_ECOL5
Sequence: MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires KbaZ subunit for full activity and stability.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Ketose 1,6-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily.
Protein: PURP_SACS2
Sequence: MIIATIGSHSALQILHGAKKEGFQTMVITDNKRENFYKNFSFIDNIYAYASLDEAVSIINGIKDYGILIPHGSLVEYLGKERVDKIETKIFGNKKIFEWEADQKKKMELLRKSNIKIPEIFERPEDVDRLVIVKLNGAKGGKGYFLARNKSEVKEGIQKLIESKMIRDENEVIIQEYVVGVPMYFQFFYSDIINRTEIFGIDIRYETNIDGLRRLPFEYMKELKINPTFVVVGNIPAVARESLLPVALEYANNFVRTTKELVPPGMIGPFCLESIITDNSDIVVFEFSGRIVAGTNLYVNGSPYSWLYWDEPMSIGRRIAREIRVANEKDKLSLVVS
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RPOA2_FRATT
Sequence: MALENLLHPTNIKIDEYAKNATKFSFEALERGVGYTLGFALKQTMLYSIAGACVTSIKINDGKVTSLEDVIPCDETVADIILNVKSLPVTLAEGVETGTITFELSGSEEEIFSEEAKLSEGLAITEEVFICSYNGGKKLKIEAKVEKGVGFRPAQDNFKDGEFLLDATFSPVVFCDFEIKDARVGRRTDLDKLELNIKTNGNVNCEEALRLAATKIQNQLRNILDIEEINKGIFVEDPTKDINPILLKHVEELNLTARSSNCLKAVNIRLIGELVQKTENELLKAPNFGKKSLTEIKDKLSELGLSLGTLIENWPQDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha 2, RNAP subunit alpha 2, RNA polymerase subunit alpha 2, Transcriptase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SYR_SYNSC
Sequence: MLSLSQSLDAQLRAAMQRAFPEADAGLDPQLASASKQEFGDFQANGALPLAKPLKQAPRQIATAIVEQLQADPAFTDLCLEPQIAGPGFINLTIRPERLAAEVSARLGDERLGVPAVSNAAPVVVDFSSPNIAKEMHVGHLRSTIIGDSLARVLEFRGHPVLRLNHVGDWGTQFGMLITHLKQVAPEALDTADAVDLGDLVAFYREAKKRFDDDEAFQSTSRDEVVKLQGGDPVSLKAWGLLCDQSRREFQKIYDRLDILLSERGESFYNPFLPAVIDGLKAAELLVTDDGAQCVFLEGVQGKDGKPLPVIVQKSDGGFNYATTDLAAIRYRFGAAPEGDGARRVVYVTDAGQANHFAGVFQVAERAGWIPDGARLEHVPFGLVQGEDGKKLKTRAGDTVRLRDLLDEAVERAETDLRSRLKEEERSESEEFIQHVAGTVGLAAVKYADLSQNRITNYQFSFDRMLALQGNTAPYLLYAVVRIAGIARKGGDLAATNAQLQFSEPQEWALVRELLKFDAVIAEVEEELLPNRLCSYLFELSQVFNRFYDQVPVLKADPEALASRLALCRLTADTLRLGLGLLGIATLDRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANE_LACLA
Sequence: MKKEVFLDKVKNGIIVSCQALPGEALYSEKGGIMPLMAKAAAQAGAVGIRANSVRDIKEIQKIVDLPIIGIIKRDYPPQKPFITATMKEIDELVATSCEVIALDCTSRERYDGLTINEFIKSIKEKYPNQLLMADCSTFEECKNAYEAGVDFVGTTLSGYTDESPKQDEPDFTLLEKLVEEKIPVIAEGRIHSPEQAKRVYDIGVDAMVIGGAITRPFEIATRFIKAIGEK
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: PSKR1_ARATH
Sequence: MRVHRFCVIVIFLTELLCFFYSSESQTTSRCHPHDLEALRDFIAHLEPKPDGWINSSSSTDCCNWTGITCNSNNTGRVIRLELGNKKLSGKLSESLGKLDEIRVLNLSRNFIKDSIPLSIFNLKNLQTLDLSSNDLSGGIPTSINLPALQSFDLSSNKFNGSLPSHICHNSTQIRVVKLAVNYFAGNFTSGFGKCVLLEHLCLGMNDLTGNIPEDLFHLKRLNLLGIQENRLSGSLSREIRNLSSLVRLDVSWNLFSGEIPDVFDELPQLKFFLGQTNGFIGGIPKSLANSPSLNLLNLRNNSLSGRLMLNCTAMIALNSLDLGTNRFNGRLPENLPDCKRLKNVNLARNTFHGQVPESFKNFESLSYFSLSNSSLANISSALGILQHCKNLTTLVLTLNFHGEALPDDSSLHFEKLKVLVVANCRLTGSMPRWLSSSNELQLLDLSWNRLTGAIPSWIGDFKALFYLDLSNNSFTGEIPKSLTKLESLTSRNISVNEPSPDFPFFMKRNESARALQYNQIFGFPPTIELGHNNLSGPIWEEFGNLKKLHVFDLKWNALSGSIPSSLSGMTSLEALDLSNNRLSGSIPVSLQQLSFLSKFSVAYNNLSGVIPSGGQFQTFPNSSFESNHLCGEHRFPCSEGTESALIKRSRRSRGGDIGMAIGIAFGSVFLLTLLSLIVLRARRRSGEVDPEIEESESMNRKELGEIGSKLVVLFQSNDKELSYDDLLDSTNSFDQANIIGCGGFGMVYKATLPDGKKVAIKKLSGDCGQIEREFEAEVETLSRAQHPNLVLLRGFCFYKNDRLLIYSYMENGSLDYWLHERNDGPALLKWKTRLRIAQGAAKGLLYLHEGCDPHILHRDIKSSNILLDENFNSHLADFGLARLMSPYETHVSTDLVGTLGYIPPEYGQASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRASEVFDPLIYSKENDKEMFRVLEIACLCLSENPKQRPTTQQLVSWLDDV
What is the function of this protein?
Phytosulfokine receptor with both a serine/threonine-protein kinase activity and a guanylate cyclase activity (PubMed:21504901).  Regulates, in response to phytosulfokine binding, a signaling cascade involved in plant cell differentiation, organogenesis, somatic embryogenesis, cellular proliferation and plant growth.  Involved in plant immunity, with antagonistic effects on bacterial and fungal resistances (PubMed:23062058).  Not involved in PSY perception.  CNGC17 and AHAs form a functional cation-translocating unit that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes (PubMed:26071421).
What are the official names of this protein?
Phytosulfokine receptor 1, AtPSKR1, Guanylate cyclase, Phytosulfokine LRR receptor kinase 1, Protein serine-threonine kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LEPA_RICAH
Sequence: MKNQKYIRNFSIIAHIDHGKSTLADRLIEHCGGLQAREMRTQVLDSMDIEKERGITIKAQTVRLVYKAKDGNTYYLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDSTQGVEAQTLANVYQAIEHDHEIVPVLNKIDLPASEPEQVKQQIEDIIGIDASEAVLISAKSGIGIDLVLEAIVNKLHPPKESSTDILKALLVDSWYDPYLGVVILVRIIDGTLRKNMRIKMMATNSVYTVENVGFFTPKKHISDVLYAGEIGFVTASIKQVADCKVGDTITDEKKPCEQALPGFKPNLPVVFCGLYPTDSSEFEHLKDSLAKLRLNDASFEYEMESSSALGVGFRCGFLGLLHLEIIQERLSREFDLDLITTAPSVVYKIHMRYGESLEIHNPADLPDLQKIESMEEPWIKATIMVPDEFLGAVLSLCTEKRGVQLDHSYIANRAKIVYKLPLNEIVYDFYDRLKSCSKGYASFEWQIDVYEPSELVKLGILVNGEVIDALSTIVHRSRAEQRGKVLCVRLKDLIPRQQIDIAIQASIGSRIIARETIKALRKDVLSKCYGGDISRKRKLLEKQKAGKKRMRQYGNIEIPQSAFIAALKIGDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KRA31_CAPHI
Sequence: MACCAPRCCSVRTGPATTICSSDQFCRCGVCLPSTCPHDISLLQPTFCDNSPVPYHVPDTYVPTCFLLNSSHPTPGLSGINLTTFIQPGCENACEPRC
What is the function of this protein?
In the wool cortex, wool keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant wool shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of wool keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 3-1, Keratin, high sulfur matrix protein, IIIB2, Keratin-associated protein 3.2, M1.2 protein.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 3 family.
Protein: MTB12_MYCTU
Sequence: MKMVKSIAAGLTAAAAIGAAAAGVTSIMAGGPVVYQMQPVVFGAPLPLDPASAPDVPTAAQLTSLLNSLADPNVSFANKGSLVEGGIGGTEARIADHKLKKAAEHGDLPLSFSVTNIQPAAAGSATADVSVSGPKLSSPVTQNVTFVNQGGWMLSRASAMELLQAAGN
What is the function of this protein?
May play a role in the development of protective immune responses.
What are the official names of this protein?
Low molecular weight antigen MTB12, CFP-2, Low molecular weight protein antigen 2.
What is the protein family that this protein belongs to?
Belongs to the MTB12 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIG_COXBU
Sequence: MTLSEQNIDKEELAKFSDLAQDWWNPAGKMKPLHLINPVRLKYIEQQITLKGKHVLDVGCGGGLLSEALAKHGAIVTGVDMSESLIDVAKNHAEQQQLNINYQCQDIEILTKDAQRFDIITCMELLEHVPDPQRMIKNCAALIKPGGKLFFSTINRNFKAYLYTIVGAEYVFNLLPKGTHDYAQFIRPSELTQWAESGGLRLLDITGIHYHPLKNEFDLSRDVSVNYLACFTHE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: AMPP2_ASPFU
Sequence: MRGSGRSDIVISAVDALDICITLARNDCDKYPGSVAAKLGVSSGLIYLVGQPTINWGDSDQPRPFRQRRYFYYLSGVEEADCYLTYDIKNDLLTLYVPDFDLHRAIWMGPTLTVKEARERYDVDQVRYHASLKGDIQRWADNYNKTSLLYILHDTQKPQVLSNELRLDDELLLPAMDAARGIKDEHEIRMIREANRVSALAHRKVLENVLRMSTEAEIEGLFLDTCISHGAKNQAYEIIAGSGENAAVLHYVKNNEPLQGRQLVCLDAGAEWNCYASDVTRTFPLAADWPTARARDIYQLVEEMQEECIKRIQKGVRFLDLQVLAHVIAIEGLMRLGILKGGSVEEIRESGASTVFFPHGLGHHVGLEVHDVSAKRLTAVEGDKEYYSSILVPSMSHCPCTLSAPLLEEGMVVTVEPGIYFSRLALANARKLAFAKYINFDEAEKYIPIGGVRIEDDILVTSSGHENLTTAPKGEEMLEIIRRGIDS
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase AFUA_1G14920, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: KTHY_MYCGE
Sequence: MNKGVFVVIEGVDGAGKTALIEGFKKLYPTKFLNYQLTYTREPGGTLLAEKIRQLLLNETMEPLTEAYLFAAARTEHISKLIKPAIEKEQLVISDRFVFSSFAYQGLSKKIGIDTVKQINHHALRNMMPNFTFILDCNFKEALQRMQKRGNDNLLDEFIKGKNDFDTVRSYYLSLVDKKNCFLINGDNKQEHLEKFIELLTRCLQQPTHY
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: EDC4_MOUSE
Sequence: MASCASIDIEDATQHLRDILKLDRPAGGSNAESQRPSSAYNGDLNGLLVPDPLSSGDGNSTNKPGIRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVKGKIQEEILVHIRQPEGTALNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHNTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGFVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPEVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQDEGRACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGTESSHGAGALESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLSTHTAHEDFTFGESRPELGSEGLASAAHGSQPDLRRIVELPAPADFLSLSSETKPELMTPDAFMTPTASLQQISASPSSSSSSSSSSSSSSSSSSSSLTAVSAVSSSSAMDPSLPRPPEELTLSPKLQLDGSLTLNSSSSSLQASPRSLLPGLLPGPADKLISKGPGQVSTAASALSLDLQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSVPEGLIEPNSMASAASALHLLSPRPRQGPELGSQLGLDGGPGDGDRHSTPSLLEAALTQEVATPDSQVWPTAPDITRETCSTLTESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDTSAEQSDHDDEVASLASASGGFGSKIPTPRLPSKDWKTKGSPRTSPKLKRKSKKDDGDSAVGSRLTEHQVAEPPEDWPALIWQQQRELAELWHNQEELLQRLCAQLEGLQSTVTDHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSVRDEIKKTVPPCVSRSLEPVAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVSSSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQATVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRSDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQADPHNSLSKAARRLSLMLHGLVTPSLP
What is the function of this protein?
In the process of mRNA degradation, seems to play a role in mRNA decapping.  Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs.  Promotes complex formation between DCP1A and DCP2.  Enhances the catalytic activity of DCP2 (in vitro).
What are the official names of this protein?
Enhancer of mRNA-decapping protein 4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EDC4 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Nucleus.
Protein: VATG1_ARATH
Sequence: MESNRGQGSIQQLLAAEVEAQHIVNAARTAKMARLKQAKEEAEKEIAEYKAQTEQDFQRKLEETSGDSGANVKRLEQETDTKIEQLKNEASRISKDVVEMLLKHVTTVKN
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase).  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase subunit G1, V-ATPase subunit G1, Vacuolar H(+)-ATPase subunit G isoform 1, Vacuolar proton pump subunit G1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase G subunit family.
What are the subcellular locations of this protein?
Cell membrane. Vacuole membrane; Peripheral membrane protein.
Protein: QUEA_BACC0
Sequence: MDINLFDFHLPEELIAQVPLEERETSRLMVLDRETGDIEHKHFTDILSYLHEGDCLVLNETKVMPARLHGVKEDTGAHIEVLLLKQEEGDKWETLVKPAKRVKEGTVISFGEGKLKATCTGTADQGGRQLEFSYDGIFYEILDELGEMPLPPYIKETLEDRDRYQTVYAKEIGSAAAPTAGLHFTEELLEKLKQKGVELAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAALLNRVKENGGRIITVGTTSTRTLETIATDHDGKLCAASGWTDIFMYPGYEFKAIDGLITNFHLPKSTLIMLVSAFANRDNVLHAYNEAVKEKYRFFSFGDAMFVASHAKMGNK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACBP3_ORYSJ
Sequence: MGLQEDFEEYAEKVKTLPESTSNEDKLILYGLYKQATVGDVNTSRPGIFAQRDRAKWDAWKAVEGKSKEEAMSDYITKVKQLQEEAAALKAVFRAYLVGEMNIFECHIGRLTRCRRGFRTQMKKQIVYSPGTREMNLLSLIKPSLAHVGYCSTYG
What is the function of this protein?
Binds medium- and long-chain acyl-CoA esters with high affinity.  Can interact in vitro with linolenoyl-CoA (PubMed:21128943).  Binds phosphatidic acid (PA) and phosphatidylcholine (PC) in vitro.  May play a role in the biosynthesis of phospholipids (PubMed:24738983).
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 3, Acyl-CoA binding protein 3, OsACBP3.
What is the protein family that this protein belongs to?
Belongs to the ACBP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ES2VB_ODOVE
Sequence: MFTMKKSLLLLFFLGTISLSLCEEERGADEEEGDGEKLMKRGLFSILKGVGKIAIKGLGKNLGKMGLDLVSCKISKEC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Esculentin-2Vb, esc2Vb, Esculentin 2VEb.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Esculentin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AAEA_ECOL6
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SCN3_MESMA
Sequence: MKLSLLLVISASMLIDGLVNADGYIRGSNGCKISCLWGNEGCNKECKGFGAYYGYCWTWGLACWCEGLPDDKTWKSESNTCGGKK
What is the function of this protein?
Binds to sodium channels (Nav) and inhibits them (By similarity).  Recombinant ANEP delays the convulsion seizure of model animals by 18% and shows anti-neuroexcitatory activity.
What are the official names of this protein?
Anti-neuroexcitation peptide 3, BmKANEP3, Anti-epilepsy peptide, Anti-neuroexcitation peptide III, ANEPIII, Toxin KIM.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_NOSS1
Sequence: MANVIVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVKGQTFKLHLIPSGILYPDTECMIGCGTVIDPQVLIKELDQLESLNISTKNLLISETAHVTMPYHRLIDKASEERRGSHKIGTTGRGIGPTYADKSERTGIRVLDLMDPAALRDQLEWTINNKNVILEKLYNLPPLDTEEVIQEYIGYAERLRPHVVDTSLKIYDAIQRRRNILFEGAQGTLLDLDHGTYPYVTSSNPVAGGACVGTGLGPTMIDRVIGVSKAYTTRVGEGPFPTELHGELGELLCDRGAEFGTTTGRKRRCGWFDAVIGRYAVRINGMDCMAITKLDVLDELEEIQVCIAYEIDGDRCDHFPTSARQFARCRPIYKTVPGWQVPTSECRTLEDLPQQALDYLKFLAELMEVPIAIVSLGASRDQTIIVEDPIHGPKRALLHPDGTPASLLSA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTC_SALPA
Sequence: MDQKQIEEIVRSVMASMGQDVPQPVAPSKQEGAKPQCASPTVTESCALDLGSAEAKAWIGVENPHRADVLTELRRSTAARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLSPEAIDALKSQCVMNPDVQVVVSDGLSTDAITANYEEILPPLLAGLKQAGLNVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRVATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: TNR5_PIG
Sequence: MVRLPLKCLLWGCFLTAVHPEPPTSCKENQYPTNSRCCNLCPPGQKLVNHCTEVTETECLPCSSSEFLATWNREKHCHQHKYCDPNLGLQVQREGTSKTDTTCVCSEGHHCTNSACESCTLHSLCFPGLGVKQMATEVSDTICEPCPVGFFSNVSSASEKCQPWTSCESKGLVEQRAGTNKTDVVCGFQSRMRALVVIPITLGILFAVLLVFLCIRKVTKEQETKALHPKTERQDPVETIDLEDFPDSTAPVQETLHWCQPVTQEDGKESRISVQERE
What is the function of this protein?
Receptor for TNFSF5/CD40LG (By similarity).  Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, CD40L receptor.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: OR30A_DROME
Sequence: MELKSMDPVEMPIFGSTLKLMKFWSYLFVHNWRRYVAMTPYIIINCTQYVDIYLSTESLDFIIRNVYLAVLFTNTVVRGVLLCVQRFSYERFINILKSFYIELLQSDDPIINILVKETTRLSVLISRINLLMGCCTCIGFVTYPIFGSERVLPYGMYLPTIDEYKYASPYYEIFFVIQAIMAPMGCCMYIPYTNMVVTFTLFAILMCRVLQHKLRSLEKLKNEQVRGEIIWCIKYQLKLSGFVDSMNALNTHLHLVEFLCFGAMLCVLLFSLIIAQTIAQTVIVIAYMVMIFANSVVLYYVANELYFQSFDIAIAAYESNWMDFDVDTQKTLKFLIMRSQKPLAILVGGTYPMNLKMLQSLLNAIYSFFTLLRRVYG
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Involved in the behavioral responses to propyl acetate and anisole.
What are the official names of this protein?
Odorant receptor 30a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or30a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.