PharMolix/UniProtQA huggingface dataset:
Protein: NCCA_ALCXX
Sequence: MIESILSGAVRFRWLVLFLTAVVGAIGAWQLNLLPIDVTPDITNKQVQINTVVPTLSPVEVEKRVTYPIETAIAGLNGVENMRSLSRNGFSQVTVIFKESSNLYFMRQQVTERLAQARPNLPAGVEPQMGPVSTGLGEVFHYSVEYEFPDGKGAKVKDGEPGWQSDGSFLTERGERLTDRVSKLAYLRTVQDWIIRPQLRTTAGVADVDSLGGYVKQFVVEPDAAKMAAYGISFEELAQALEDANLSVGANFIRRSGESYLVRADARIKSADEIARAVIAQRQGVPITVGQVANINVGGELRSGAASRNGYETVVGSALMLVGANSRTVAQAVGDKLEEIKKTLPPGVVIVPTLNRSQLVMATIKTVAKNLVEGAALVVVILFALLGNWRAAVIAALVIPLSLLISAIGMNGLNISGNLMSLGALDFGLIIDGAVIIVENSLRRLAERQHHEGRLLTLKERLEEVILSSREMVRPTVYGQLVIFMVFLPCLTFQGVEGKMFSPMVITLMLALASAFVLSLTFVPAMVAVLLRKKVSEKEVRVIAVTKERYRPLLERAVARPMPFLGAALVTLALAAMAFTFVGREFMPTLDEQNLNLSSVRIPSTSIDQSVAIDLPLERAVLSLPEVQTVYSKAGTASLAADPMPPNASDNYIILKPKSEWPEGITTKEQVIERIREKTAPMVSNNYDVTQPIQMRFNELIGGVRSDVAVKIYGENLDDLASTAQKIAAVLRKTPGATDTRVPLTGGFPTFDIVFDRAAIARYGLTVKEVADTVAAAMAGRPSGQIFDGDRRYDIVIRLPGQQRENLDVLGALPVMLPAVEGQPRASVPLRQLVQFRFTQGLNEVSRDNGKRRVYVEANVGGRDLGSFVDDAAKRIAAEVKLPPGMYIEWGGQFQNLQAATQRLAIIVPLCFILIAATLYMAIGSAALTATVLTAVPLALAGGVFALVLRDIPFSISASVGFIAVSGVAVLNGLVLISAIRKRLEDGAAPNEAVIEGAMERVRPVLMTALVASLGFVPMAIATGTGAEVQKPLATVVIGGLITATVLTLFVLPAVCGMVLRRQKKLEKPGGELLEA
What is the function of this protein?
Component of the NCC cation-efflux system that confers resistance to nickel, cobalt and cadmium.  May form a membrane tunnel, which allows ion transport across the membrane.
What are the official names of this protein?
Nickel-cobalt-cadmium resistance protein NccA.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VSX1_CHICK
Sequence: MPGRADPSGGRAAVPVPLPVAVAAAPSPASVRSALPERSARPGGAGLRAKGFAITDLLGLEAELQPPPGAAPGPAGGYEGGGALGLGLGLLCGLAGPGAPCLLPAPLPLLPARGPRPGPPGPPPAARRHKESASDEDSLSGDASELKMPASQIKRKKRRHRTVFTAHQLEELEKAFNEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESIINSAKSGLVGSCAPWLLGMHKKSMEVSRKAESQEKPADGWQAEQDGEELQGKQASSQRSSEKLGPAKDPEDTAIDLSRTAKQEKRSVLRQCVNGDPTTEQKDRDH
What is the function of this protein?
Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster.  May regulate the activity of the LCR and the cone opsin genes at earlier stages of development (By similarity).  Dispensable in early retinal development (By similarity).
What are the official names of this protein?
Visual system homeobox 1, Homeobox protein Chx10-1, Transcription factor VSX1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUCC_POLSJ
Sequence: MKIHEYQGKEILRNFGVPVPRGIPAFTVQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGVKVAKTIDDVKRIAGEILGMQLKTHQTGPEGQKVRRLYIEDGADIQKEYYVSAVTDRESQKVAFIASSEGGMDIEEVAHSNPEKIIKVFVDPLVGMTDAQAKEVAAGIGMPADSVAQTVDVLQKLYKCYMETDASLVEINPLNRNSKGEIMALDAKFNFDANALFRHPEIVAYRDLDEEDPAEVEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATAEKVTEAFKIMLKNPEVKGILVNIFGGIMKCDTIADGVITACKAVNLSVPLVVRMKGTNEDLGKKMLADSGLPIIAADTMAEAATKIVAAVK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MON1_ASPCL
Sequence: MNSKASEQPQVSPGDNEHAQDGSTSCAKNCARYTNDDASAALEERLPPLPPRPSTLSFLDEGYTSSRSIRQTSQVNLQAKATTAVSLTDIGFRQSSEGDGEDHSAPDFPEPLRAKASLNQPKTSKGSDAGDSTSIGSTIPNVELGEVENVFSDFLAAEPSAPQEDGSGLLQFPEFRADDAEDEFATEFEPIGDLNEQGENEELLLERWKSKRKHYLILSAAGKPIWTRHGDGGLISGYVGVIQTIISFYEDAKDHLSSFCAGDTKFVVITRGPLHLVAISRLHESDTQLKSQLEALYMQILSTLTLPSLTHLFSVRPSTDLKRPLQGSETLLSTLADSFTKGSPSSLLSALECLKIRKSHRQAINNALLKTRVGSLLYGLVVAGGRLVSVVRPKKHSLHPGDLQLLFNMIFEAEGVKAGGGENWIPVCLPGFNSSGYLYMYVSFLDLREDSGSTANETATKEESVAIILISTKKESFFELQGMRNAFVEQMDKNESIKIIKEAIKRGRPTTTDIVPGTVLHHFLYKSRANVQFTMSAYGPESSSTFRLRRLMSTYNDLHSSVHAKHAHVKVHHCVSQSTSSFAWVTPRFELYCVASPNANRNALAQSASKIVQWVQQEEERLFIIGGAVF
What is the function of this protein?
Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
What are the official names of this protein?
Vacuolar fusion protein mon1.
What is the protein family that this protein belongs to?
Belongs to the MON1 family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: CINAL_ECOSM
Sequence: MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVGDNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHEAWLKEMERYFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVMVEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDSLQLPPGVTMGYRSSMPIIELKLTGPASEEQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQSRQFSLTLSEQFTGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGFENEHLNFALATPDGTFALRVRFSTTRYSQAIRQEVCAMMALNMLRRWLNDQDIASEHGWIEVVESMTLSV
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: TRPD_METTM
Sequence: MRFEGIMNDIMDFRNLSEDEAHDLMEMIMDGEMGDVQIAALLTALAMKGETVDEITGFARAMRERAVKVKIPESMRVVDACGTGGDRFKSYNVSTAAAIIAAAAGVKVAKHGNRAVTGSCGGADILEAAGVNIELGPEAACRSLETLGIAFMFAPLFHRATARVAPVRRELGFKTVFNILGPLTSPASAEVQLLGVFDPYLVGPVAEVLRNLGVKRAMVVHGFDGNMNPAMDEISTVGPTLVGFLEDDEIGIKRLMPPDFGVDVGQLQHLKAASTVDGNLRMFMDVLAGLDDTPGRKSRLDIALANAGALIYLAEMEDTLEGGTEAARETVESGAALRLMEDFASFTQNL
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: VPU_HV1N5
Sequence: RKVDRIIDRIRERAEDSGNESEGDQEELSALVEMGHDAPWDVNDL
What is the function of this protein?
Enhances virion budding, by targeting human CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its receptor human CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to interfere with the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo (By similarity).
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: YIDC_ALCBS
Sequence: MEIQRALVITGIAVVSYLMIQAWQRDYANTASPVPVEQVAEQGNSSSSDSADLPSVQSQTDNSIPSAQSDNDLPSVSPADIAQPTPSSQRIEVNTDVLRVEINPVGGDIVRLALPDYPKHVDTPDQPFVLMDQNSNGTYVAQSGLVGKNGTDSSKGRPHWNSAQQSYRLAEGDNELNVDLTLTQDSGAEIIKRYTFEKGSYLIRVSHIVRNNGSTPWTGALYGQIKRDGRDDPGLSKAGFAPMPTYLGAAYWSADKPYNKLTFDDMSEDDVKLDQTVEGGWLAMVQHYFVSAWIPDAKQKNHYSSVYLKSRDQYLLRFVSPNTTIQPGEESVLYSEFYAGPKQQDNLEAISPGLNMTVDYGWLWFISQPIFALLVFLQSGEVSVFGMDIDIGGGVGNWGVAIILLTLIIKAIFFKLSATSYRSMAKMRKVAPEMQRIKEQNKNDKQKQQMETMNLFKREKINPLGGCLPMLVQMPVFIALYYVLLESVELRQAPFFLWINDLSVMDPYFVLPILMGASMFLQTRLNPTPADPTQAQVMKWMPMIFAVFMLWFPAGLVLYWLTNNILSIAQQWIITRNIENSA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF2_PELPD
Sequence: MSKIRVSNLAEKLGLEHKEVLARLKEIGVDAKTATSLVDEDVLKKLMPSLSPDGAEEVRVTTTIIRRRAKAAPVVEPAPAAVAESLEEKPAEPVAPAAPTPPEVPAAAPAPPKAAAAPAEAATMNARIIAPPPAPVETAAPVAAAPVAAATAPPEKALPTPPVVEAPVVEAKPEPVVEKPKVPAQPDKPSANQARILGRMEIPGVTTRPTRVVRRDGTVAPAAEHAQRRPSPAAGAPSRGAAPDRSRMKPATLPPSAPPAADDRRKFGGKSAAPHSEGAGKGGKKGGASTAKKKEQPKKHEILEKRERVFDPVYRGSRKKVKERASETRKTEITIPKAIKRIIKISETISVGELAKRMGIKANDLIKSLMKMGMMVTINHALDFETTVILASEYGYEVENMAVDLDEILESTPDAPETLVKRPPVVTIMGHVDHGKTSLLDAIREANVIAGEAGGITQHIGAYDVELNGRKITFLDTPGHEAFTAMRARGAKVTDIVILVVAADDGVMPQTREAINHSKAAGVPIVVAINKIDKPEAKPERVKQELMEFGLVASEWGGDATMVEVSAKKRLNLEGLLEMVLLQADLMELKANPDKEAKGTIVEAKLDRGRGPVATVLVQEGTLKNGDYCVVGVHSGRVRAIHNDRGEKVNEAGPSMPVEVIGLSGVPDAGDVFVSLKDEKQAKEIATLRQIKQREIEMAKHSKVTLEDLYKQIQSGDVKDLNVIVKGDVQGSVEVVSDSFRKLSTDAVRLNVIHSGVGAITETDVNLAAASNTIIIGFNVRPEVKAQAMAEKEGVDIRLYSIIYDAVEDVKKAMEGLLDPTLKEKYLGRAEIREVFSVPKIGNIAGSYVQDGKMLRNAQARLLRDNVVIYEGKLSSLRRIKDDVKEVAAGYECGIGLENYNNIRIGDIIEAFEIEKVATKL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y111_CUPMC
Sequence: MTNKGRAGTGPAPCPCGNGAYDTCCGRFHRGEASPPTAEALMRSRYSAYVLGDVSWLRQTWHASTCPPDLSADPGTNWLGLTVKSHAQQDATHATVEFVARYKVGGRAHRLHELSRFVFESREPGEASRWLYVDGDLREPA
What are the official names of this protein?
UPF0225 protein Rmet_0111.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: GEP3_YEAST
Sequence: MLNLCHALRGVRQFSCSVIVKVKCASCSIKLQDQDPSKPGYYTKPKSLPDSKLNPDLQDLKYLLFSQDIQLSKQATQNDPDLKTKRDLLLRVICKRCSNALHHNNYNPEEFPESTLNDILNYVPRGSNVMHIVPFVEFPLHLDPNVLKRNDLDTTLVLTKSDQVFKDKNAVSKKVPIFMKQFLKNTLRIDSNKTFAISALKNWNISMFYNYFKNYTYLLGNPNVGKSTLINTLLQKYLGYKVKIDSTGKINSPSEEVMQEAFTNPKNFFKIQAAGVSHIPNLTRSVQAYQVGGKILFDLPGYSTSTSRLRLEELIDERWLQRLRKTDLFNRKHIKQKTYESMKGTSQGGCYTVGGIFYLVPPKGSINQIVKYIPGPSKTFKNIEKGIDVFNSCNSSSGTHPLSRYCGIKSVICEKSQYKRYAIPPFIGSIEIVLKDIGYILLRTTGRYEFKGLHEIWIPRGIQVGIREPLENLIESGYQRYIETNGKESSCPRDRPIISSLYEMAPDEADTLNAVKKSYLEKTEKDLSARRFVDDDPYDLVQHLEKKKNPYWYYQW
What is the function of this protein?
Interacts genetically with prohibitins and thus may be involved in the mitochondrial lipid metabolism.
What are the official names of this protein?
Genetic interactor of prohibitins 3, mitochondrial, Altered inheritance of mitochondria protein 40, Found in mitochondrial proteome protein 38.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ALKR_ACIAD
Sequence: MDALSKIFDDIHLNKSEYLYVKTQGEWAFHMLAQDALIAHIILMGSAHFTLQDGTTQTAYSGDIVLIPSGQAHFVSNDAQNKLIDCSNIQSFFDGHRNDAIELGTTSSDHGLIFTVRSHIDMHMGSPLLNALPSLIHIHHAMSSTGPEWLRVGLYFVALETQRIQPGRDKIFDHLMSILFIECVRDHIAQLDDPKSWLTALMHPELSNALAAIHAYPEKPWTVESLADQCCMSRSKFATLFQSIVHETPLAYLQQHRLRLAVQLLKTSQLNIQQIANKVGYSSETAFSQAFKRQFEQSPKHYRQQS
What is the function of this protein?
This protein activates the expression of the alkane 1-monooxygenase AlkM.
What are the official names of this protein?
HTH-type transcriptional regulator AlkR.
Protein: DAPEL_LACLM
Sequence: MINLIEIRRQLHQIPEIGLEEHKTQKYLLTIIHQIIQNKSFIQVETWQTGLLVYLKGSQGQKTIGWRTDIDGLPVEELTNLPFASKNGRMHACGHDIHMTVALGLLEKLSESQPKNNLLFLFQPAEENEAGGKLMYDGGAFKNWLPDEFYGLHVRPDLKVGDIATNEQTLFAGTCEVELTFVGTGGHAAFPHTANDALVAAAYFVTQVQTIVSRNVDPLDSAVVTFGKMEAGTTNNIIAERAFLHGTIRSLTQEVNELTQKRLTELAKGVAQSFDMTIDLKLKQGGYLPVENNPKLAKELMDFFRNETKANLIDIAPAMTGEDFGYLLSKIPGVMFWLGINSEAPLHSQKMQADEGVLDFAVEAIGQFLDIKANRN
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: PRMC_BUCAI
Sequence: MNIKKWIKKSIQKLSHVDNPKFESELLLSYVTKHTRSFIISSDEIQLTEKQYKYLNHLIHRRSLGEPIAYIIKEKEFWSLSLCVSYDTLIPRPDTEILVERALSKIKSNSACILDLGTGCGAIALALASINSNWNIIGIDKSENALAIARINASKLNFKNVTFFFSDWFLNIKKKFNIIVSNPPYVSKKEIKFFKKDIFFEPLSALISDNNGLSDIENIIKNSKHYLFYGGWLMIEHGWRQKVKVQYLFKKYNFHEIESYQDYGGNDRVTIGKKYDK
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, M.BusHemKP, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: SAP11_ORYSJ
Sequence: MAQREKKVEEPTELRAPEMTLCANSCGFPGNPATNNLCQNCFLAASASSSSSSAAASPSTTSLPVFPVVEKPRQAVQSSAAAAVALVVERPTAGPVESSSKASRSSSVNRCHSCRRRVGLTGFRCRCGELYCGAHRYSDRHDCSFDYKSAARDAIARENPVVRAAKIVRF
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 11, OsSAP11.
Protein: IP21_SOLLC
Sequence: MAVHKEVNFVAYLLIVLGMFLYVDAKACTRECGNLGFGICPRSEGSPLNPICINCCSGYKGCNYYNSFGKFICEGESDPKRPNACTFNCDPNIAYSRCPRSQGKSLIYPTGCTTCCTGYKGCYYFGKDGKFVCEGESDEPKANMYPVM
What is the function of this protein?
Potent inhibitor of both trypsin and chymotrypsin.
What are the official names of this protein?
Wound-induced proteinase inhibitor 2, Wound-induced proteinase inhibitor II.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I20 (potato type II proteinase inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTQC_ECOLI
Sequence: MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVAEMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQIIMDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQYGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTMPTGLGAFFNTNGSVAALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANALKF
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II ChbABC PTS system is involved in the transport of the chitin disaccharide N,N'-diacetylchitobiose (GlcNAc2) (PubMed:10913117).  Also able to use N,N',N''-triacetyl chitotriose (GlcNAc3) (PubMed:10913117).
What are the official names of this protein?
PTS system N,N'-diacetylchitobiose-specific EIIC component, EIIC-Chb, IIcel, N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIC component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS14Z_PYRHO
Sequence: MAKADYNKRKPRKFGKGARRCIRCGQYGPIIRIHGLMLCRHCFREVAPKLGFRKYE
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RL13_SALAR
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS12_NITEC
Sequence: MPTISQLVRKPRKAKQVKSKVPALESCPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGYEVSSYIGGEGHNLQEHSVVLIRGGRVRDLPGVRYHTVRGSLDTAGVKDRKKARSKYGSKRPKSA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: HIS7_CYBJA
Sequence: MAERTVKPQRRALVNRTTNETKIQISLSLDGGYVTVPESIFKDKKYDDATQVTSSQVISINTGVGFLDHMIHALAKHGGWSLIVECIGDLHIDDHHTTEDVGIALGDAVKEALAYRGVKRFGSGFAPLDEALSRAVVDLSNRPFAVVELGLKREKIGDLSCEMIPHFLESFAQAAHITMHVDCLRGFNDHHRAESAFKALAVAIKESISSNGTNDVPSTKGVLF
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
Protein: YOPE_BACSU
Sequence: MIGLAYFLIIWLGVGLLTGIKFIFVDQVYDEEFKELMDKETAAGMERNLASLFFKNKLNVIAFFMLIGLLPLAMRITKLFKRG
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YopE.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF3_GEOMG
Sequence: MAKPTVNVNQAIRAREIRVVGANSEQLGIMPLNEALALAESQQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEAKKKQSHVVVKEVKLRPKTDEHDLQFKIKHVRRFIEEGNKAKVTLVFRGREITHMEFGVRALERVASEIEDIAVIEMKPKMEGRSMFMIVAPKVKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECU_LIGS1
Sequence: MVFHYPNGRAYDYHKNENHPSLVNKVNHRSINHNRSKTIYGNRGMSLEEEINESNQYYLSQGIAVIHKKPIPIQIVSVDYPKRSAAVIKEAYFKQASTTDYNGVYKGKYLDFEAKETTNISSFPLRNFHAHQVEHMRACQKQGGICFTIVKFTKTDELFILPADLLFKYWDEQDKSRKSIPKAEIEQLGYKLNYSISPRIPFLKGVDLLIANS
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_CHLTE
Sequence: MVNSKASSFRFSFFIHNSAFIILFPPSFSRLLFIPAIGYLQDHLQSLSTSRLMSEERLVSGNIIDYPAPVYSYRRRVTREVPFGTIFLGGYLPIRVESMITAHTMDTAASVEQCRRLYEAGCEIIRLTVPTEKDAENLKNIREQLRRDGIDTPLVADIHFSAKAAMKAVEFVENIRINPGNYATGAKFSSKDYTDDEYRAELDKVREEFTPLVRKARSLGVSMRIGTNHGSLSDRIVSRYGNSPEGMVEAALEFSRICEDEGYYDQLFSMKSSNVRVMIQAYRLLVARADAELRYAYPLHLGVTEAGDGDEGRIKSAMGIGALLEDGLGDTIRVSLTEDPVNEVPVGFAIVKKYNDMLLVRGDRAHLPVKHVIEHERKSAGHVQLPFEPFSYSRRPSISIDGAGIPVGGDALPGVETAAHAPITDTESLRDEILARLDPGKPEDAIRSELVSVGVGSAEDISLLKALLDSLGNLREKIVVSTADTSIVPALLPLCGRVRLDIVEGETLGTGLIESLHDRNAAIEFCFIHEKSSENVPAEVLVRLAAKLKARGLQRVMLSIVSDAPLYSTRKLALELKKAGLDYPIAVRYRRLDGERSGVLIQSAIQAGTLFCDGIGDLIALETNMPASEEVSLCFNILQAARIRMSKTEFISCPGCGRTYFELEKTTALIKQRVSHLKGLKIGIMGCIVNGPGEMADADFGYVGSGKGRVSLYVGKECVEENIPEAEALERLIELIRQNGKWVDPV
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.