PharMolix/UniProtQA huggingface dataset:
Protein: TEKT1_CANLF
Sequence: MAKLLQPSPKFLPEEWHIANKNQYHRAEAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVRFWKKELDDKLEQLVCTTEDLLTYQTRLQNALESLKEPLHITQMCLEYRDKRIGIDLVHDEVEQELLKEAEVIHGVMALLTRTMDEVTEQIRLNRSAKYNLEKDLKDKFVALTIDDVCFSLNNNSPGIYYSDSVVRVEPHSVSLEDWLDFSNTNVEKANRQRNNSLALKALVDRILSQTADDLRRQCDMVDTAFQMGLKETKAARDQLAAHLAKVMEEIACQEKNMTVLEKAILDQEGPAKVAHTRLETRTRRPNVELCRDVAQYRLVKEVGEIAQNVGRLKEALAQAQVELKGLNRRQLALQEEVQVKENTIYIDRVLCTHMRKSNPLRDGGDQGQWARACAPTPSAEDGTSHTD
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme.  Forms filamentous polymers in the walls of ciliary and flagellar microtubules.
What are the official names of this protein?
Tektin-1.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: XPT_STRPB
Sequence: MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQKYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQVTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQDGRRLIEDMGIEVTSLARIKNFENGNLNFLEADA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYHD_CPVBM
Sequence: MADVAGTSNRDFRGREQRLFNSEQYNYNNSLNGEVSVWVYAYYSDGSVLVINKNSQYKVGISETFKALKEYREGQHNDSYDEYEVNQSIYYPNGGDARKFHSNAKPRAIQIIFSPSVNVRTIKMAKGNAVSVPDEYLQRSHPWEATGIKYRKIKRDGEIVGYSHYFELPHEYNSISLAVSGVHKNPSSYNVGSAHNVMDVFQSCDLALRFCNRYWAELELVNHYISPNAYPYLDINNHSYGVALSNRQ
What is the function of this protein?
Major component of the virus occlusion bodies, which are large proteinaceous structures (polyhedra), that protect the virus from the outside environment for extended periods until they are ingested by insect larvae.
What are the official names of this protein?
Polyhedrin, C-polyhedrin.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Strain H polyhedrin is found in the cytoplasm, while strain A is found in the nucleus.
Protein: DDL_ENTHA
Sequence: MKITLLYGGRSAEHDVSVLSAFSVLNAIYYTYYQVQLIFISKEGQWVKGPLLTEKPTSKEDLHLTWDPSGKVTDGFTGRVINPGEIKEEGTIVFPVLHGPNGEDGTIQGFLETLNLPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKENPKKIFDQCEGSLLYPMFVKPANMGSSVGISKAENREELQNALALAYQYDSRAIVEQGIEAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYDAKYINNKIEMQIPAEVPEEVYQKAQEYAKIAYTMLGGSGLSRCDFFLTNKNELFLNELNTMPGFTQFSMYPLLWENMGLKYGDLIEELIQLGINRFNQRQGFFEANE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2A_THEAC
Sequence: MNIKPLPDNGDLVVVKITEVKNFGANGVLEEYPGVEGYIHISEVATGWVKHIRSYLREGQRVVCKVIGVNPERKVVDLSLKRVNQHQSREKIAEWKNEQKADKLFEIVCSRLNRNPEECKEQFGRRLVELFGTLFAAFESAAQSNGEWLPEMNGDWKNVFVEIAKENITIPEVSVSGYFEVYSLASDGVERIKEVLTIPEDTGKVELEYVGAPRYRIVVKDKDYKKAEEILKKVVQIVNEKAKKLQVEVEFNKQ
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit alpha, aIF2-alpha, eIF-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
Protein: Y3666_ECOL6
Sequence: MPGYTEYVLAEGSFSYGQAVAVITAYRNVFIQDDPGMHFRRVIRNAEGQRRWRCRNSEADAGKQLNAWLASGGLLRQ
What are the official names of this protein?
UPF0401 protein c3666.
What is the protein family that this protein belongs to?
Belongs to the UPF0401 family.
Protein: MTNN_PHOLL
Sequence: MKVGVIGAMEQEVTLLRNQIEDRQTLSRGGCEIYTGKLNGVEIALLKSGIGKVSAAIGTTLLLEHCQPDVIINTGSAGGLDPKLQIGDIVVSREVRYHDTDVTAFGYEPGQMAQCPAAFVADDQLIDLAEKCIHSLNLNAVRGLICSGDAFINGAEPLARIRATFPQVTAVEMEAAAIGHVCHQYNTPFVVVRAISDVADKESHISFDEFLAVAARQSTLMVNAMLATLSKDK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: KV51_METSE
Sequence: MKLQLIVVLLIALVIVSLVDGEMLEKRCKNRLKKCTSNSECCDKKDRGGRKLRCLTXCDERHCLTYKQCLFYPGLQKVKRLCFTYCRCTI
What is the function of this protein?
Neurotoxin (By similarity).  Blocks voltage-gated potassium channel (Kv) (By similarity).  In vivo, induces a rapid increase in swimming speed on zebrafish larvae, as well as death which occurs between 2 and 18 hours later (By similarity).
What are the official names of this protein?
U-metritoxin-Msn2a, U-MTTX-Msn2a, Toxin MsePTx1.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 5 potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: BETA_ECO27
Sequence: MQFDYIIIGAGSAGNVLATRLTEDPNTTVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNALDLDNWAQEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVITSKPGVNPLFEAMIEAGMQAGYPRTDDLNGYQQEGFGPMDRTVTPHGRRASTARGYLDQAKSRPNLTIRTHAMTDHIIFDGKRAVGVEWLEGDSTIPTRAAANKEVLLCAGAIASPQILQRSGVGNAELLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPRIGAEWLFGGTGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSPSRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRTTREIMHQPALDQYRGREISPGVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMAVVDGEGRVHGLEGLRVVDASIMPQIITGNLNATTIMIGEKIADMIRGKEALPRSTAGYFVANGMPVRAKK
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: PHNHY_PSEPU
Sequence: MTQLINVNSRSYRLSSAPTIVICVDGCEQEYINQAIQAGQAPFLAELTDFGTVLTGDCVVPSFTNPNNLSIVTGAPPSVHGICGNFFFDQETQEEVLMNDAKYLRAPTILAEMAKAGQLVAVVTAKDKLRNLLGHQLKGICFSAEKADQVSLEEHGVENILARVGMPVPSVYSADLSEFVFAAGLSLLINERPDFMYLSTTDYVQHKHAPGTPEANAFYAMMDSYFKRYHEQGAIVAITADHGMNAKTDAIGRPNILFLQDLLDAQYGAQRTRVLLPITDPYVVHHGALGSYATVYLRDAVPQRDAIDFLAGIAGVEAVLTRSQACQRFELPEDRIGDLVVLGERLTVLGSAADKHDLSGLTVPLRSHGGVSEQKVPLIFNRKLVGLDSFDRLRNFDIIDLALNHLA
What is the function of this protein?
Specifically hydrolyzes phosphonoacetate.  Does not have activity on other organophosphonates or acetates (By similarity).
What are the official names of this protein?
Phosphonoacetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase family. PhnA subfamily.
Protein: SLMA_SALNS
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKNTSTRLRLIVLLILGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDENLLASQLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: KUP2_GEOMG
Sequence: MVQEHTESFWGGIIKSMGLVFGDIGTSPIYTLTVIMTLTKPDAEHVLGILSLIVWTLIILVSVEYAWLAMSLGRKGEGGTIVLKEILVRLLKSGRQVAFVGFLAFMGVSLLLGDGIITPAISILSAVEGMRLIPGWENLAQGVLIFIAAVIALILFIFQFKGTDKVAGAFGPIMVIWFGALTLSGIVSIAGTPEVVSAVSPHHAVTFLMHNGLAGFFILSEVILCATGGEALYADMGHLGRKPIIRAWYFVFSALVINYLGQGAFILRNPNETNILFSMVKSQAPILYIPFLCLTIMATIIASQALISGVFSIVYQGITTRILPLMKVDYTSTHLKSQIYIGSVNWSLLVAVIFIMLIFKKSENLAAAYGLAVTGTMFITGIMMTMIFSHTTKKWKVPIALAVTLIDLVYLTANFHKLPHGGYWSLILASIPLAIMIIWTQGQKALYRALRPLDLDTFLLSFGQIYAKGHNIPGTGLFFVRETAVVPPYVIHCIIRSNIIYERNVFVSLNRSDEPFGVKANLTKGIGPGLDSFEILAGYMELVDIERLLKKKGIEEKVIFYGIEDIATNNPFWRVFSTIKRQTANFVQFNKLPVSKLQGVVTRVEM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSRA_SALG2
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: RPOC2_RANMC
Sequence: MAERADLVFHNKAIDGTAMKRLISRLIDHFGMAYTSHILDQVKTLGFQQATTTSISLGIDDLLTIPSKGWLVQDAEQQSLILEKHHNYGNVHAVEKLRQSIEIWYATSEYLRQEMNPNFRMTDPSNPVHIMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTTRGISVSPRNGMITERIFIQTLIGRVLADDLYMGSRCIAIRNQDIGVGLVNRFITFRSQPISIRTPFTCRSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPDNGKIKFNEGLVYPTRTRHGYPAFLCYIDLSVTIEGPDILHNVNIPPKSFILVKNDQYVESEQVIAEIRAEASTLNFKERVRKHIYSDSEGEMHWSTAVYHAPEYTYGNVHLLPKTSHLWILSGVPQRSSIVPFSLHKDQDQINIHSLSAKQKFISNLSLSMTNDQVIKKLFRSDSSVKKGGWVLDYSGPAEVLCNGHCNLIYSAILDENSDLLAKRRRNRFTIPLQSNQEKEQKPRSGISIEIPINGLFRINSILAYFEDPRYRRKSSGITKYGTIEVDSIVKKEDLIEYRRTKEFRPKYQMKIDRFFFIPEEVHILPGSSSIMIRNNSIIGVDTRITFNIRSQVGGLVRVEKKKKKIELKIFSGNIYFPGETDPISWHSGILIPPGAGKKNSKESKKLKNGIYVQRITPTKKKYFVLVRPVVTYERADGINLAALFPQDPLQERDNVQLRVVNYILYGNGKPIRRISHTNIQLVRTCLVLNWDQDKKGSSIEEVRASFVEIKINALIRDFIKMDLVKYPISYTRKRNDPVGSGLIPVNGSDHTNLNPFYSKASIKQSLIRHQGTIRTLLNKNKECQSLITLSSSNCSRIDPFNRLKYHNNMIKKSNKRDILPPIRNLLGPLGIIPKITNFFSFYYLITHNQILVKKNSQLDNLKRTSPVLKYYLIDENGRIFNPDPSINMILNPFNWNWYFIHHDYCEETSTIINLGQFFCENVCISKSGPHLKSGQVLIVDVDSLVIRSAKPYLATPGATVHGHYGEILYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISMNLENRVEGWNERITRTLGIPWGFLIGAELTIAQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEDGMSNVFSPGELIGLLRAERTGRALEEAICYRAVLLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGMIPVGTGFKGLVHRLSNISLEIEKKNLFKGGMRDILFHHKELFDSCIPRNFPDTSEQLFTKQSFTRFTD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DPOLX_MIMIV
Sequence: MNSKIIEQFNLLEKQVDAEYLNSKVENDLKEETMNRFRLKSIKKALSILKNLDFEITDANDVKGIPGIGAGTIKRIKEILETGKLHDLKDKFSPEKQKQIEGIQELENVIGIGSSTAKKLISQYGIRSVDDLKKAIETGKVKVSTSIMLGLKYYGIVQRDIPRKEITAIEKLLSKEAHKIDPDLEIIICGSYRRGKKTSGDIDVLMYHPKMKTSKEMLHPEKFDLEPYFNLYIDRLTEKGFLIDDITFNPNKKYMGFCKYKLNPVRRIDIRFIPYNSLAPAMLYFTGPMELNTKMRSAAKKRKMILNEYGLFKTDKNGAQIPLDTKSEADIFHALGMDYLTPQQRELYSSGKIH
What is the function of this protein?
Repair polymerase.
What are the official names of this protein?
Probable DNA polymerase family X.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Virion.
Protein: GPDA_PAULE
Sequence: MRISILGAGAWGTALAIALAERHDVVLWGRSEDAMAQRARSXENTAYLPGHPLPAALKATADFSLALDHVAQGDGLLIAATSVAGLRPLAQQLQGKAIPNLVWLCKGLEEGSGLLPHQVVREVLGTQLPAGVLSGPSFAQEVAQGLPCALVIAAEDAALRELVVAAVHGPAIRVYSSDDVVGVEVGGAVKNILAIATGILDGMSLGLNARAALITRGLAEITRLGIALGARAETFMGLAGVGDLILTCTGDLSRNRKVGLGLAQGKPLETIVTELGHVAEGVRCAAAVRNLAQQLQIEMPITNAVAGILFDGHSPRATVEQLLARHPRDESISAS
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QTRT2_PONAB
Sequence: MRLSLTKVVNGCRLGKIINLGKTGDHTMDIPGCLLYTKTGSAPHLTHHTLHNIHGVPAMAQLTLSSLAEHHEVLREYKEGVGKFIGMPESLLYCSLHDPVSPCPAGYVTNKSVSVWSVAGRVEMTVSKFMAIQQALQPDWFQCLSDGEVSCKEATSIKRVRKSVDRSLLFLDNCLRLQEESEVLQKSVIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGNPTTLETRLRLLSSVTAELPEDKPRLISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETLLQQNGTQEEIKCMDQIKKMETTGCNQEITSFEINLKEKKYQEDFNPLVRGCSCYCCKNHTRAYIHHLLVTNELLAGVLLMMHNFEHYFGFFHYIREALKSDKLAQLKELIHRQAS
What is the function of this protein?
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Note=May associate with the mitochondrion outer membrane.
Protein: MRGA1_MOUSE
Sequence: MDNTIPGGINITILIPNLMIIIFGLVGLTGNGIVFWLLGFCLHRNAFSVYILNLALADFFFLLGHIIDSILLLLNVFYPITFLLCFYTIMMVLYIAGLSMLSAISTERCLSVLCPIWYHCHRPEHTSTVMCAVIWVLSLLICILNSYFCGFLNTQYKNENGCLALNFFTAAYLMFLFVVLCLSSLALVARLFCGTGQIKLTRLYVTIILSILVFLLCGLPFGIHWFLLFKIKDDFHVFDLGFYLASVVLTAINSCANPIIYFFVGSFRHRLKHQTLKMVLQNALQDTPETAKIMVEMSRSKSEP
What is the function of this protein?
Orphan receptor activated by a subset of RFamide-family neuropeptides such as FLRF-amide and FMRF-amide.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  Its effect is mediated by G(q) and G(11) proteins.  May regulate the function of nociceptive neurons by modulation of pain perception.
What are the official names of this protein?
Mas-related G-protein coupled receptor member A1, RF-amide G-protein coupled receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Protein: GSPE_ECOLI
Sequence: MRIHSPYPASWALAQRIGYLYSEGEIIYLADTPFERLLDIQRQVGQCQTMTSLSQADFEARLEAVFHQNTGESQQIAQDIDQSVDLLSLSEEMPANEDLLNEDSAAPVIRLINAILSEAIKETASDIHIETYEKTMSIRFRIDGVLRTILQPNKKLAALLISRIKVMARLDIAEKRIPQDGRISLRIGRRNIDVRVSTLPSIYGERAVLRLLDKNSLQLSLNNLGMTAADKQDLENLIQLPHGIILVTGPTGSGKSTTLYAILSALNTPGRNILTVEDPVEYELEGIGQTQVNTRVDMSFARGLRAILRQDPDVVMVGEIRDTETAQIAVQASLTGHLVLSTLHTNSASGAVTRLRDMGVESFLLSSSLAGIIAQRLVRRLCPQCRQFTPVSPQQAQMFKYHQLAVTTIGTPVGCPHCHQSGYQGRMAIHEMMVVTPELRAAIHENVDEQALERLVRQQHKALIKNGLQKVISGDTSWDEVMRVASATLESEA
What is the function of this protein?
ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
What are the official names of this protein?
Putative type II secretion system protein E, T2SS protein E, Putative general secretion pathway protein E, Type II traffic warden ATPase.
What is the protein family that this protein belongs to?
Belongs to the GSP E family.
What are the subcellular locations of this protein?
Cell inner membrane. Note=Membrane association is not an intrinsic property but requires the GspL gene product.
Protein: DER_CYTH3
Sequence: MSNIVAIVGRPNVGKSTFFNRLVGARIAIMDDESGVTRDRHYGEAEWCGKFFTVIDTGGYVTGSDDIFEGQIRDQVDIAIDEADVILFLVDSDVGVHHLDQEFANKIRRSKKPVILVANKSDNNKRLHMSAEFYELGMGEVWPISSQNGTGTGELLDEVISHFKDEGEEDPNKGIPRIAVLGRPNAGKSSYVNALLGTNRSIVTDQAGTTRDSITSHYNVFGKEFIFVDTAGIRKKSRIKEDVEYYSILRSVKALEESDVCVIMIDAERGIESQDMNIIWMAHNNKKGIVILVNKWDLIEKDSKTAQVFQENIREALKPIDYPLIMFISVLNKQRLFQSVEAIMKVYENRGKRIPTSELNDKILKEIDYNPPPATKQKYVKIKYVTQLPTKSPTFAFFCNLPQYVGESYSRFLEHKIRGYFDFEGVPISIVYRKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RRAA_HAEIG
Sequence: MFIDTSELCDLYAEQVDVVEPIFSSFGGVSNFYGKVTTVKCFESNGLIAEVLEENGEGRVLVIDGGGAVRRGLIDAELAQLAVDNGWEGIIVYGAVRQIQQLENLDIGIHALAPIPVSADESSAGESDIPVNFGGVTFFPEDYIYADLTGIILSQEPLDLED
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_PHOLL
Sequence: MSLNFLEFEQPIAELEAKIDSLTAVSRQGEKLDINLDEEVQRLREKSLELTRKIFSDLGAWQIAQLARHPRRPYTLDYIQHIFTDFEELAGDRAYADDKAIVGGLARIDGRPVMVIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLSVPVICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSAEKAPLAAEAMGITAPRLKELELVDTVISEPLGGAHRDYEAISTSLKAQLLIDLAELDHLTSEELVNRRYQRLMQYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAL4C_MOUSE
Sequence: MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKDLMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYDRFENFLISKVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESELCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKSEKSYIFLHPSIQEVCAAIFYLLKSHMDHPSQDVKSIEALIFTFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLSEGQEHSYTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQCLQHLDLNLTFLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRNKTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKNQNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKTLWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRITDFDKETQELLMAEEEKNPHLSILSSV
What is the function of this protein?
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 4C, NALP-alpha.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
Protein: DPOLB_RAT
Sequence: MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
What is the function of this protein?
Repair polymerase that plays a key role in base-excision repair.  Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap.  Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
What are the official names of this protein?
DNA polymerase beta.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Cytoplasmic in normal conditions. Translocates to the nucleus following DNA damage (By similarity).
Protein: TPIS_MORSP
Sequence: MQAWVIGNWKQNPATSHDVNALLDDLCAAISTTKQMSHDNSARCQIMVAPSLIHLAAVNGRLKDTSILCAAQDVSGHSASVGAYTGECSAQQIVDAGATWTILGHSERRQYHQESNDALLQKMIHALSQDLGVVFCIGESQEQYDTKQTLTVIDNQLVVIKEFITQQPELIDALPTRLIIAYEPVWAIGTGKVPTVAEVSATHKHIKQTLAGFADSLSNMTVLYGGSVNADNANSFAADPMIDGALVGGASLKADSFLTIATAFSQASI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_ALTMD
Sequence: MSFTVVIPARFGSSRFPGKPLALIDGKPMIQHVVERAKEAGAESIIVATDDERIQNVVEGFAQVCMTSVDHQSGTERIAEVIQTQNISGDTIVVNVQGDEPFIPAENIKQVATNLANAPQCQMATLSTPIVSVADVFNPNIVKVLVNEKGESIYFSRSPIPFERDYMMANPNKANTALYNRHIGIYAYRADYVNQYVNYAPSALEQIESLEQLRAIWYGDKIHCEVAVAPPPVGIDTPEDLERLLETI
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.