PharMolix/UniProtQA huggingface dataset:
Protein: RPB9A_ARATH
Sequence: MSTMKFCRECNNILYPKEDKEQKILLYACRNCDHQEVADNSCVYRNEVHHSVSERTQILTDVASDPTLPRTKAVRCSKCQHREAVFFQATARGEEGMTLFFVCCNPNCGHRWRE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  Component of RNA polymerases IV and V which mediate short-interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements.  Required for RNA silencing.
What are the official names of this protein?
DNA-directed RNA polymerases II, IV and V subunit 9A.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RSMH_AQUAE
Sequence: MEVLHKPVLLRESVEFLTENGGKIYVDCTLGGGGHAKEILKKRKDIFLIGIDRDEEAIEIAKENLKEFEGRFSIYKANFKDLDLVLKEEGIDKVDGFLFDLGVSMYQLKGERGFTFQEDQPLDMRMDKEQTLTACKVVNNYPERELIRILKEYGEEKFAVRIAKAIVQRRKKKPIETTGELVDVILSVVPEYYKHGKIHPATRTFQAIRIEVNKELESLKEALEKTPYHFNSKGRLVVITFHSLEDRIVKHFIKEKEKEGIFRIITKKPVTPSEEEIRENPASRSAKLRVAEKI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_PSET1
Sequence: MTLDSSKYPLLNLVNEPAHLRDLAQDKLPAFSHELRDYLLNSVSQSSGHLASGLGTVELTVALHYVYNTPDDRLVWDVGHQAYPHKILTGRRDLMHTIRKKDGLHPFPFREESQYDTFSVGHSSTSISAALGMSIAAQKEGKGRKTVAVIGDGAITAGMAFEAMNHLGDVKSDMLIILNDNEMSISENVGALTNHFARILSGSFYTNIREGSKKLLSGVPPVKQLASKMEEHIKGMMIPGTFFEELGLNYIGPIDGHDVNMLVDTLRNMRNLKGPQLLHIKTQKGKGYKPAEADPIGYHGVPKFDPNTSSLPKSKPGAATFSNVFGDWLCDIAKQDSKLMAITPAMREGSGMVRFSKEHPDQYFDVAIAEQHAVTLAAGFACEGLKPVVAIYSSFLQRAYDQLIHDVALQNLPVLFAIDRAGIVGADGETHQGAYDLSFMRCIPNMVIMAPSDTNECRHMLYTGYQANCPVAVRYPRGSAGTAEIATNMQLLEIGKADVVKQGAKVAILSFGTLLENAQLAADELNATLVNMRFIKPLDTALLDELINSHDVIVTLEDNAISGGAGSAVNEYLATQKAQVSILNLGIPDEFIKHGTQDEMHDEMGLGEQGILTAIKAFIN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RAPA_SHEB5
Sequence: MPFALGQRWISDTESELGLGTVVQVEGRMVTVLFPATGENRMFSRAEAPLTRVIYNPGDSVESHEGWSLAVSELTEKDGIVIYHGIHSETGEQVTLRETLLNHNIRFNKPQDRLFAGQIDRLDRFGVRYQCQMLRHKLASSDLLGLQGPRVGLIPHQMWIAHEVGRRYAPRVLLADEVGLGKTIEAGLIIHQQLLTGRAERILIIVPDTLRHQWLVEMLRRFNLRFSVFDEDRCVEAYADHDNPFYTEQLVICSLELLRKKKRLDQALDADWDLLVVDEAHHLEWTEEAPSRAYQVVEALSEVIPGVLLLTATPDQLGHESHFARLRLLDPDRFYDYDAFLAEEDSYKDVAIAAEALAGNTKLPDAAINSLTELLGEKDISPSIRLIQADGIDAEVQQAARSELLQELLDRHGTGRVLYRNSRASVKGFPKRFFNAYPHAMPDQYQTAARVSGMMGGHKSLEAKAAQALSPEKLYQEFEDNSASWWKFDPRVDWLIEFLKSHRSKKVLIIASQAETALSLEEALRTREGIQATVFHEGMSIIERDKAGAYFAQEEGGAQALICSEIGSEGRNFQFASHLVLFDLPLNPDLLEQRIGRLDRIGQKNDIQIHLPYLEDTAQERLMQWYHQGLNAFELTCPSGHVLYSEFAEDLLNVLAVDDSDELTNLLNHTQSRYKELKHAMEQGRDKLLEINSHGGEKAMAIVQRLAQNDGDTHLIGSVIRLWDIIGVDQEDKGENSIILRPSEHMMFPTYPGLPEDGVTVTFDRDTALSRDDIALITQEHPLVQTGLDLITGSETGTTSVAILKNKALPAGTLFLELIYMADASAPKSSQLYRYLPPTPIRVLLDKNGNDLSAKVDYASFDKQLSAVNRHIGGKLVTASQPILHPLFAKGEEYAQVVVDEMVAQAREKMTQQLSAERSRLESLKAVNPNIREEELEYLRNQMQELNTYLDASQLQLDAIRMVLVSHV
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: HRTB_STAHJ
Sequence: MNLAWKEIKFYRFRYTLIMLIIFLLGSMVLFISGLAQGLARENISYLNNMPAEHYIVEDNKEPKLESSQLNQSQQNKIEKIIHENATQMGTQTLKINQQDQDVITLNTPKHLTPKLVSGNYPKKQNEIAISEKLTGNDLKVGDTVTFKGHHHNYKISGIMNESMYSHSSMILMNKEAFKSLNKQVSTFYPVDKINKDNKESLKQIKGIKVVNEKALTDNIASYQAEQMPLNLMIISLFVITAIVLSAFFYVMTIQKIPQIGILKAIGIKTKHLLTALLLQIILTTMVGVILAFSVILILNAFMPVTMPFYLSYSQVLLMIVVFLIVGLIGALLSFIKVLKVDPIEAIGGME
What is the function of this protein?
Part of the ABC transporter complex hrt involved in hemin import.  Responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Putative hemin transport system permease protein HrtB.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APM1A_ORYSJ
Sequence: MAAAEQSAEQFRGQARLPGFAAPRRYDLRLVPDLDGCAFTGSVDVSVDVTAPTRFLVLNAAELEVSPGGVQFKPHGAEQELHPAEVTNVPEDEILIIRFNEVLPVGEGTLVIAFKGTLNDKMHGFYRSVYELNGEKKNMAVTQFEPADARRCFPCWDEPSFKAIFKITLEVPSETVALSNMPVVEEKVNGLIKAVYFQETPIMSTYLVAVIVGMFDYVEAFTTDGTRVRVYTQVGKSAQGKFALEVAVKTLVLFKEYFAVPYPLPKMDMIAIPDFASGAMENYGLVTYRETALLFDEKHSAAANKQRVAVVVAHELAHQWFGNLVTMEWWTHLWLNEGFATWVSYLAADNFFPEWNVWTQFLEESTTGFKLDALAGSHPIEVDVNHVDEIDEIFDAISYRKGAAVIRMLQSYLGAETFQKSLAAYIEKFAYSNAKTEDLWAALEEGSGEPVKTLMHSWTKQQGYPVVNVKLKDGKLEMEQTQFLSSGAEGVGQWVVPITLCCCSYSRQEKFLFNGKQEDFNLSGLVECQKKEDFWIKLNVNQTGFYRVSYDEELASRLRYAIEANKLSAADRYGVLDDTYALCMAGKQKLVSLLHLIAAYKDETEYTVLARVIDTSLSIVEMVAVAAPEGLGKLKKFLIDFLEPFAQRIGWDAKSGEGHLDALLRGTLLTALAELGHEATINEAVRRFNIFVEDRETPLLPPDVRKAAYVALMQTVNKSNRAGYESLLKIYKETDLSQEKVRILGSLASCPDPDVVRDTLDFMLSPEVRNQDSIFLLRGVGAAGHEVAWTWLKEKWDYISDTFSGTLLTYFVSTTVSPLRTDEMGDDAEEFFKSRTKANIARTVKQSIERVRINAKWVESTRAEANLGNVLKEISHDH
What are the official names of this protein?
Aminopeptidase M1-A, Alpha-aminoacylpeptide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm. Note=The dileucine internalization motif may be involved in intracellular sequestration.
Protein: ACDD_METTH
Sequence: MLMDKLTELLKLLQNTESIEINEFRMDVEELELYLMPAVQQAIQKTVEVREAVEALPAEEFNPPIRSYPGEVAQVKLGEGTRKSVYLGGQKALYRFEEPQPNPPVVTFDVFDIPMPGLPRPIREHFSDVMEDPGDWARKAVKEYGANMVTIHLIGTGPKVMDKSPREAAKDIEEVLQAVDVPLVIGGSGDPEKDPLVLEKAAEAAEGERCLLASANLDLDYRKVARAALDHNHAVLSWAITDVNMQKTLNRYLLKEGLKREDIVMDPTTCALGYGIEFSIDVITRTRLAALKGDSDLQMPMSSGTTNAWGSREAWMKKDEWGPTDYRGPLWEIVTGLTMMLSGVDIFMMLHPTSVRLLREIGETFTREYMTAETPDLREWITELDYQEV
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).  Probably maintains the overall quaternary structure of the ACDS complex.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit delta, ACDS complex subunit delta, Corrinoid/iron-sulfur component small subunit.
What is the protein family that this protein belongs to?
Belongs to the CdhD family.
Protein: COAX_HALHL
Sequence: MRLLLDLGNSAIKWAVVPPGGAAWQTGRLAYADGAGPEDTAAALGGRIPSTVAPARICVASVLAPAWQRRFDTALERAWGGPVQHLVASAAAAGVTNGYDQPEQLGVDRWAALIGARAVAPEGACIVDVGTAITVDGLDADGRHLGGAIFPGARLLHQALARGTARLPDSPIGAAALPARSTEEGIAAGVAVGAGAAVTALADAILAACPPGAQRLITGGGGGELAAGLSPAWCHRPYLVLEGLLHWSRHEARR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_STRS2
Sequence: MAEITSAKATARTVRVSPRKSRLVLDNIRGKSVADAIAILKFTPNKAAGIIEGVLNSAIANAENNFGLEKANLVVSEAFANEGPTLKRFRPRAKGSASPINKRTAHITVVVAEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: NU4LM_BOSIN
Sequence: MSMVYMNIMMAFTVSLVGLLMYRSHLMSSLLCLEGMMLSLFVMAALTILNSHFTLASMMPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IBMP_CAMVB
Sequence: MEDIEKLLLQEKILMLELDLVRAKISLARAKGSMQQGGNSLHRETPVKEEAVHSALATFAPIQAKAIPEQTAPGKESTNPLMVSILPKDMKSVQTEKKRLVTPMDFLRPNQGIQIPQKSEPNSSVAPNRAESGIQHPHSNYYVVYNGPHAGIYDDWGSAKAATNGVPGVAHKKFATITEARAAADVYTTAQQAERLNFIPKGEAQLKPKSFVKALTSPPKQKAQWLTLGVKKPSSDPAPKEVSFDQETTMDDFLYLYDLGRRFDGEGDDTVFTTDNESISLFNFRKNANPEMIREAYNAGLIRTIYPSNNLQEIKYLPKKVKDAVKKFRTNCIKNTEKDIFLKIKSTIPVWQDQGLLHKPKHVIEIGVSKKIVPKESKAMESKDHSEDLIELATKTGEQFIQSLLRLNDKKKIFVNLVEHDTLVYSKNTKETVSEDQRAIETFQQRVITPNLLGFHCPSICHFIKRTVEKEGGAYKCHHCDKGKAIVQDASADSKVADKEGPPLTTNVEKEDVSTTSSKASG
What is the function of this protein?
Enhances the ribosomal termination-reinitiation event leading to the translation of major open reading frames on the polycistronic viral RNAs.
What are the official names of this protein?
Transactivator/viroplasmin protein, Tav, Inclusion body matrix protein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae viroplasmin family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in cytoplasmic occlusion bodies.
Protein: RL31_PROM5
Sequence: MPKSEIHPKWYPDAKVICNGEVVMTTGSTKPELHVDVWSGNHPFFTGTQKILDTEGRVDRFMKKYGMGSADSATSQETKEAKESDK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: T131L_BOVIN
Sequence: MAGPRRPQPGCYRRTAAAVNLLLGVFHVLLPCGRPGGAQGQAIEPMPNVVELWQAEEGELLLPTQGDSEDDTEEQSQEQSFSDKLFSGKGLHFQPSVLDFGVQFLGQPAAKILYAYNPSRESEVVVNSVFTAARHFHVPPVHCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSHGVLSYHVSGFGTRVMSAKGSAEQLPNAYFLLPQVQTVQLSQTQAETTNSSLLQVQLECSLHNKVCQRLKSCYVESDDVLRLQMSIIVTMENTSKEFEENTQDLLDHLSIIYVATDKSESSDDSAVNMYILHSGNSLIWIQDVRHFSQRDVLSLQFEPVLLPTSTTNFTKIASFTCKAPSCESGAREDGKKKDTPTLKACLSSPVVQGYFRMDPSATQFHIENHENTSGLWSLWYLNHFDHGVVLNDVFVSKETKHVLKILNFTGPLFLPPGCWKIFSLKLAVKDIAINVFTHVFLTTNIGAVFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAENPDWEGSLSLDPSTWDVDSELANTLYERWKKLKHGDVCKRTVLGVTRFAHSKKSKESEPFAVFLPRLVPEPGLVLNFSATALRNSMVKYFVVKNPSSWPVSLQLLPVSLYPKPEAAARLLHKWFGTDMQMINLTTSEFQLTKACPYLGVRSEGSRFGILHLHLQPLERKRVGVVFTPADYGKVSSLILIRNNLTVIDMIGVEGFGARELLKVGGRLPGTGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPITVTSLKINGYNCQGYGFEVLDCHQFSLGPNTSRDISIVFTPDFTSSWVIRELTLVTAADLEFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNASSSSQQSTAPVDVISAHSHKSNCKNFLDAYAPSDKGRGKSCLPVSSPQSRTQNATKRSPATCGHSQKKHKCSVYYGRHRGAAVASSAGAPSEDRPAPAKAGGCPAGAGEAWVGLRCAGGLSANLQKSLALPRSFLGKDENTLKSAVAASSPSSECHVKEGAQTCVFPKETDFQVSESVAELKEREVCPMKTPKKLPENHLPRSSPQCQSDLPDISRKNNGNNQQVPVKNEVDNCESLKKVDTKSSSEKKIHKAAKEDGCSEKQDIPSIEQEDPYRKKALQEKKEGNVQNLNWNKNRMCRKNKKRGAAQVLRPSDQSELKLVCSEFERSELSSDINVRNWRIQENPGEACKAGASSGSSLPATQGEAEGYFQKPGKKGAEKSCSDSGSDCGSSSGSVRASRGSWGSWSSASSSDGDRKPAVGPPRCLLPGDSVSQNDFSSEAPISLNLSRNICNPTDVSGLPAPADAPCPSLPAGPAAAEEQGLCAPGDLWPAQPVCVTGGFGCALESGGPAALPPPAAVPSSSFIDWNATCEGQFPSVYCPLELNDYNAFPEEGMNYPSGFPCPAEVQTDFIDHSSPSAWGSPPSVPTAWGHASLISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCAINPTTEHSAHMENQAVMCKEYYPGFNPFRAYMDLDIWTSTANRNANFPLSRDSSYCGNV
What are the official names of this protein?
Transmembrane protein 131-like.
What is the protein family that this protein belongs to?
Belongs to the TMEM131 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NU4LC_LOLPR
Sequence: MMFELVLFLSVYLFSIGIYGLITSRNMVRALICLELILNSINLNLVTFSDLFDSRQLKGDIFAIFVIALAAAEAAIGLSILSSIHRNRKSTRINQSNLLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MUTS2_LISMH
Sequence: MEKKVEAILEFDKIKKQLTEFASSSLGEQAILELAPATDFQVVQKTQLETEEGAKIIRLRGSAPITGLTDVFAHLKRLEIGGDLNGLEIYQIGSNLRVSRQMKNFMNDLLEIGVEIPLLGALSDELLVLKEVEEDIAISVDESGKVLDTASEALSTIRRTLRRTEDRVREKLESYLRDRNASKMLSDAVITIRNDRYVIPVKQEYKGHYGGIVHDQSASGQTLFIEPQSVVDLNNERKALQAKEKQEIERILAEISASLAAWINEIHHNTFILGRFDFIFAKARFGKAMKAVTPHLSDAGVVHLIAARHPLLDAAKVVANDIYLGEDFTTIVITGPNTGGKTITLKTLGLLTLMAQSGLQIPAQEDSTIAVFEHVFADIGDEQSIEQSLSTFSSHMTNIVSILENVNQKSLILYDELGAGTDPQEGAALAIAILDASHAKGASVVATTHYPELKAYGYNRVHATNASVEFNVETLSPTYKLLIGVPGRSNAFDISRRLGLSENIITEARSLVDTESADLNDMISSLEEKRNLAETEYEEARELARGADSLLKDLQKEISNYYQQKDKLIEQASEKAATIVEKAEAEAEEIIHELRTMQLNGAAGIKEHELIDAKTRLGNAKPKTINKTIPQAPKQKPHVFQEGDNVRVLSLGQKGTLLNKISDKEWNVQIGIIKMKIKTADLEYIQPEKPKKQRIITSVHSSGSPAKSELDLRGERYEDALQKVDKYLDEALLAGYPQVAIIHGKGTGALRTGVTEYLKNHRMVKSIRFGAAAEGGNGVTIVEFK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: Y4A8_ENCCU
Sequence: MAESVASSESLPQMKPEEPESKKSPSREAIPKDMPVVNVRDIMMYVENMEGMENKKLIPYVVYLDEQFKEIVQKRRKDARVVFIFMIAIMSMLVIGLVVCGVKLLGYLMEQK
What are the official names of this protein?
Uncharacterized membrane protein ECU04_1080.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYM_METBU
Sequence: MSKFPSEKPVLVTCGLPYANGKAHVGHLRTYVPADIFTRSLKKTGQEVTFVCGSDTHGTPIVFNAEELKTTPTEIIKVYHKHFDEIFKKMGVMLDAFGTTDDPTNHNRTTEIVSKLIENGYVYPKTIEIAYCPSCDRSLPDRYVKGTCPHCKKEARGDECDQGCGKHLEPGELEHPACTTCNGPAEYKQQEHFFFKLSQFKDFLLEYLEGLGGTLNARNYALGWVKQELTDWCITRSLDWGIKFPGHEDLVVYVWVDAPIGYIAFTEEWAEANNESWEKFWKDDGSIIHFIGGDIIYHHCIFWPAMLKGAGYNQPDAVVASGMVKIEDRTFSKSRGYVVWVDEDYLDHGFHQDLLRYYLASYTSHTKELNFSWKVFQDKVNTELVGVFGNFLYRTLLFTHKNFGEIPEGEVKQDILDEINTTIENAKEAMENYEFKKYADTVMALASYGNTYFQSNEPWKLIKENKEACGEIVKNCAQITKALCLLFEPILPEKMEEAWKQIGMETDVHETNYMEATELVKSGTTLEKPSILFEKIEDEKTEEMEAISAARVKEAIAKENGTEEVEEVKEIEEMKDLITFDDFSKLDIRIGTIVSAEAIKKSKKLLKLQVDLGEEETRQIVAGLKESHEPEQLIGKQVAVLTNLAPAKLCGVESNGMVLAGVDAADNAILLQPEKETNPGTCIH
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC1_STRP6
Sequence: MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKYAGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTFLWVELAQHDHLYLLPVLAAVFTFLSTWLTNLATKEKNVMMTVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 1, Foldase YidC 1, Membrane integrase YidC 1, Membrane protein YidC 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARYL_CHICK
Sequence: MNIQEYFSRISFDGSHKDADLQTLTAIFQHHIQAIPFENLSMHCGETIDLDLQATYNKIVKKKRGGWCMETNYLLFWALKEMGYDICVLGGNSYEPAKKAYTDEINHILLKVVIKGSSYIVDAGFGGGPYQTWLPMLLISGKDQPQIPGIFRFIEDNGIWYLEKVKRKHYVPEGSVPLTDNPEMGNIRKLYSFTLEPKHIDDFQELNAYLQVAPDTILQKKSICSLQTTDGFYALVGWTFSEMKYKYKEDADLLQTTTLTDEEVEKTLKDKFNIVLENKLIPVNVRG
What are the official names of this protein?
Arylamine N-acetyltransferase, liver isozyme, Arylamine acetylase.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
Protein: 1433E_TOBAC
Sequence: MAESTREENVYMAKLAEQAERYEEMVEFMEKVAKTVDVEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEDHVSSIKEYRGKIEAELSKICDGILNLLESHLIPVASTAESKVFYLKMKGDYHRYLAEFKTGAERKEAAENTLLAYKSAQDIALAELAPTHPIRLGLALNFSVFYYEILNSSDRACNLAKQAFDDAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDTTVSLSLSQKYTPTNADAPTNNTVHTSKSFLGSA
What are the official names of this protein?
14-3-3-like protein E.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: GCST_LISW6
Sequence: MTELLKTPIHPLYAKYGAKTIDFGGWDLPVQFAGIKAEHEAVRTDAGLFDVSHMGEILVKGPDSTSYLQYLLSNDIEKIKIGKAQYNIMCYENGGTVDDLVVYKKSETEYILVVNAANTEKDFEWMVQNVRGDVTVTNVSAEYGQLALQGPSAEKILSKLTDVDLSSISFFGFIEDVEVAGVKTIISRSGYTGEDGFEIYMASADAGKVFEAILAEGVAPIGLGARDTLRLEAVLALYGQELSKDITPLEAGLNFAVKLKKEADFIGKEALIKQKEAGLTRKLVGIELIERGIPRHDYPVFLNDKEVGIVTSGTQSPTFGTNIGLALIDTAYAELGQELEVGIRNKKVKAKIVQTPFYKRAK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: DGT1B_RHILO
Sequence: MYTDADRSREVVPEKDGHDKKWRDEFGRDYGRIIHSASFRRQQGKTQVFPSRESDFFRNRLTHSLEVAQIAQGIAERINYDYDKDLGGKIDPRLCATAGLVHDIGHPPFGHNGESALDKAMQRYGGFEGNAQTLRILTRLEKKLRYAEPLAGDDRAGLNLCHRTIAATLKYDNEIPAIRKAADGFVKGYYGSEKIIVDRVKASVLNGYVLGAEEKFCTIECSIMDLADDIAYSVYDLEDCFKVGFLSPAEMLASDDALLSAVAKRASKPMKRTVTINEIQAVFMEIFSEIIEQPAEDADSPLDGIVIEDDIAQQAKRDESLLTFAEAYRTSKVMSEDGYKRTEFSSELVHQFISGVELKAHKECPSLSQIYLPEKLMLRKEVLKQYTFVAAIYAPRVKLGEYRGYDLVTDIFKALMGDRGDLLMPADVRGRIRKAPNVSVKAREVCDFVAGMTDRYAMEFWARLNSDAAESMFKPI
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: FETP_DECAR
Sequence: MARTVNCIKLGREAEGLDFPPYPGPLGQRIFEHVSKEAWQQWIKMQTMIINENRLNLVDAKHRKYLAEQVEKHFFGEGADQIQGYVPPAA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: ZIM17_YEAS7
Sequence: MIPRTRTLLQSKIPITRYFARCWAPRVRYNVCRTLPAAALHTNIIAHNEVKKDDKKVHLGSFKVDKPKMMIAFTCKKCNTRSSHTMSKQAYEKGTVLISCPHCKVRHLIADHLKIFHDHHVTVEQLMKANGEQVSQDVGDLEFEDIPDSLKDVLGKYAKNNSENASQLPHPSQK
What is the function of this protein?
Involved in protein import into mitochondria.  Acts as a Hsp70-specific chaperone that prevents self-aggregation of the matrix Hsp70 chaperones SSC1 (mtHSP70) and SSQ1, thereby maintaining their function in mitochondrial protein import and Fe/S protein biosynthesis.  May act together with PAM18 as co-chaperone to facilitate recognition and folding of imported proteins by SSC1 in the mitochondrial matrix (By similarity).
What are the official names of this protein?
Mitochondrial protein import protein ZIM17, Mitochondrial import inner membrane translocase subunit TIM15, mtHsp70 escort protein 1, mtHsp70-associated motor and chaperone protein TIM15/ZIM17, MMC.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=Soluble matrix protein loosely associated with the inner membrane.
Protein: SSRP_SINFN
Sequence: MAQKGSERTIRKVVAENRKARFNYEIVDTYEAGLVLTGTEVKSLREGKANISESYATDEGGEIWLINSYLPEYLQANRFNHETRRRRKLLLSKREVNRLQGAVNREGMSLIPLKIYFNDRGRAKLELALGKGKKLHDKRETSKERDWNRQKNRLLKERG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SSTT_PECAS
Sequence: METQQSRFLQYITRGSLVQQILLGLAAGIILASLSTQAALAAGLLGTLFVGALKAVAPILVLVLVMASIANHQQGQKTNIRPVLFLYLIGTFSAALIAVVLSVLFPSTLALNAQAADITPPSGIVEVLEGLLMSVIANPIHALLNANYIGILVWAVGLGIAFRHGSGSTKSMINDASNAVTMIVRVVIRFAPLGIFGLVASTLAETGFGALWGYAHLLMVLIGGMLLVALVVNPLIVYWKIRSNPYPLVLRCLRESGVTAFFTRSSAANIPVNMELCRKLNLDEDTYSVAIPLGATINMAGAAITITVLTLAAAHTLGIQIDVPTALLLSVVASLCACGASGVAGGSLLLIPLACSMFGISNDIAMQVVAVGFIIGVLQDSAETAVNSSTDVMFIAAVCHAEDAKLAEKERLNLL
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.