PharMolix/UniProtQA huggingface dataset:
Protein: LAP_SWPVK
Sequence: MDPVCWICKDDYSIEKNYCNCKNEYKVVHDECMKKWIQYSRERSCKLCNKEYNIISVRKPFSQWVFSIKDCKKSAILYATLFLCTFIISLVLTRINITKIIDTSKNDVSFKLVTMIFYLLPFVITCISFITLIVYLYKYCKISAKNNTYDTIYEL
What is the function of this protein?
E3 ubiquitin-protein ligase which promotes ubiquitination and subsequent degradation of host MHC-I and CD4 molecules, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.  Binds target molecules through transmembrane interaction.  The result of this ubiquitination is the enhancement of the endocytosis of the target chain and the delivery to the lysosome, where it is proteolytically destroyed.
What are the official names of this protein?
E3 ubiquitin-protein ligase LAP, Leukemia associated protein, LAP, RING-type E3 ubiquitin transferase LAP.
What is the protein family that this protein belongs to?
Belongs to the poxviridae LAP protein family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network membrane. Host early endosome membrane.
Protein: WRKY9_ARATH
Sequence: MGFDFSTSKSKAKRQKRIEVRFASPLMGIDLSLKLEAEEKKKEIEGSKHSRENKEDEEHDASGDEDEQMVKEDEDDSSSLGLRTREEENEREELLQLQIQMESVKEENTRLRKLVEQTLEDYRHLEMKFPVIDKTKKMDLEMFLGVQGKRCVDITSKARKRGAERSPSMEREIGLSLSLEKKQKQEESKEAVQSHHQRYNSSSLDMNMPRIISSSQGNRKARVSVRARCETATMNDGCQWRKYGQKTAKGNPCPRAYYRCTVAPGCPVRKQVQRCLEDMSILITTYEGTHNHPLPVGATAMASTASTSPFLLLDSSDNLSHPSYYQTPQAIDSSLITYPQNSSYNNRTIRSLNFDGPSRGDHVSSSQNRLNWMM
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
What are the official names of this protein?
Probable WRKY transcription factor 9, WRKY DNA-binding protein 9.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBY_CROS5
Sequence: MDWRVLVVLGPILIAAGWAGFNIAAAAIRQVQGFFNKEA
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: NANT_YERPA
Sequence: MSISVGPSREDKPLSGGAKPPRWYKQLTPAQWKAFVAAWIGYALDGFDFVLITLVLTDIKQEFGLTLIQATSLISAAFISRWFGGLVLGAMGDRYGRKLAMITSIVLFSFGTLACGLAPGYTTLFIARLIIGIGMAGEYGSSSTYVMESWPKNMRNKASGFLISGFSIGAVLAAQAYSYVVLAFGWRMLFYIGLLPIIFALWLRKNLPEAEDWEKAQSKQKKGKQVTDRNMVDILYRSHLSYLNIGLTIFAAVSLYLCFTGMVSTLLVVVLGILCAAIFIYFMVQTSGDRWPTGVMLMVVVFCAFLYSWPIQALLPTYLKMDLGYDPHTVGNILFFSGFGAAVGCCVGGFLGDWLGTRKAYVTSLLISQLLIIPLFAIQGSSILFLGGLLFLQQMLGQGIAGLLPKLLGGYFDTEQRAAGLGFTYNVGALGGALAPILGASIAQHLSLGTALGSLSFSLTFVVILLIGFDMPSRVQRWVRPSGLRMVDAIDGKPFSGAITAQHARVVTQK
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS18_LACJO
Sequence: MAQQRRGGRRRRKVDFIAANHIDYIDYKDVDLLKRFISERGKILPRRVTGTSAKNQRKLTVAIKRARVMGLLPFVAED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y4009_MYCSJ
Sequence: MASTDDPAGQRPSRAEAIVAHAEQSISEDAIVAAARERAVDIGAGAVTPAVGALLSVLARLTEAKAVVEVGTGAGVSGLWLLSGMREDGVLTTIDVEPEHQRIAKQAFIEAGIGPSRTRLISGRAQEVLTRLADESYDLVFIDGDPADQPQFVVEGVRLLRPGGAIVVHRAALGGRAGDAAANDAEVSAVREAARLIAEDERLTPVLVPLGDGLLVAARD
What are the official names of this protein?
Putative O-methyltransferase Mjls_4009.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: NUOK_DICC1
Sequence: MIPLQHGLLLAAILFVLGLTGLVIRRNLLFMLICLEIMINAAALAFVVAGSYWGQPDGQVMYILAITLAAAEASIGLALLLQLYRRRQTLNIDTVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYV_VIBVY
Sequence: MEKTYNPTSIEQDLYKTWEEQGYFKPHGDTSKESYSIMIPPPNVTGSLHMGHAFQDTIMDTLIRCERMKGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTKHDYGREAFIDKIWEWKGESGGTITKQLRRLGASVDWDRERFTMDDGLSNAVQEVFVRLYEDDLIYRGKRLVNWDPKLHTAISDLEVENKDTKGHMWHFRYPLADGVKTADGKDYIVVATTRPETMLGDTGVAVNPEDPRYQDLIGKDIILPIVDRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHQLPMINILTFDANIRDAAEVFTTNGEPSDAYGTELPAKYHGMERFAARKAIVAEFDELGLLEEVKDHDLQVPYGDRGGVVIEPMLTDQWYVRTAPLAKTAVEAVENGDIQFVPKQYENMYFSWMRDVQDWCISRQLWWGHRIPAWYDNQGNVYVGRSEEEVRQNHNLESVIELHQDEDVLDTWFSSALWTFGTQGWPEQTDDLKVFHPSDVLVTGFDIIFFWVARMIMMTMHFVKDENGKPQVPFKTVYVTGLIRDENGDKMSKSKGNVLDPIDMIDGIDLESLVEKRTGNMMQPQLAAKIEKNTRKTFENGIEAYGTDALRFTLAAMASTGRDINWDMKRLEGYRNFCNKLWNASRYVMMNTEEQDCGFGAGEIEYSLADKWIESQFELAAKAFNNHIDNYRLDMAANTLYEFIWNQFCDWYLELTKPVLWKGTEAQQRGTRRTLITVLEKTLRLAHPVIPYITETIWQSIKPLVDGVEGETIMLQSLPQYDEANFNQEALDDIEWVKAFITSIRNLRAEYDINPGKPLEVMLKADEKDAARLEANKQVLMSLAKLESVRVLAAGEETPACATALVAKSELMIPMAGLIDKDAELARLDKEVAKTQGEIKRIEGKLGNEGFVAKAPEAVIAKEREKLEGYQETLAKLEEQKATIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETG_PROM2
Sequence: MIEPLLCGIVLGLVPITLLGLFVSAWNQYRRGSGMLDID
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RH1_ORYSJ
Sequence: MVVAMATKEEEGGPSSRVPHLPWMRNPVDIDSFSGCPVAHLPRLDPRLVKPLQRMGIESFFPVQVAAWLETIGPGAFERDICINSPTGSGKTLAYALPIVQMLATRKVRCLRALVVLPTRDLALQVKEVFDAIAPVVGLSVGSAVGQSSIADEVSNLIEKSKQGLFPSLDEEYIQMEPQTKVDILVATPGRLMDHISMTKGFSLEHLQYLVVDETDRMLREAYQSWLPTVIQLTRSSDQNHSWSDMNGETLLHPLTTIRRSGVERGFKGKSFPRLAKIVLSATLTQDPSKLSQLELQHPLLLNSGKKRYRIPTKLQSYKLVCKSNLKPLSLIVLLQELRGEKCLVFTSSVESSHRLSTLLEFFEDLPFKFSEYSRLQRESTRRKTLDAFKEGKIDVLIGTDRMARGIHIDGLRYVINYDMPPYVKTYIHRAGRTARAGESGSCFTFLRKHEVKAFDKMLKKADNSSCSLHSLPEESVETLRPVFSSALKKLEESLESEATKKSKSGDKAPNASKRKRTINT
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily.
Protein: OTC_PIG
Sequence: GGQPLQNKVQLKGRDLLTLKNFTGEEIKYILWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGVNESLKDTARVLSSMTDAVLARVYKQSDLDILAQEASIPIINGLSDLYHPIQILADYLTLQEHYGALKGLTLSWIGDGNNILHSIMMSAAKFGMHLQVATPKGYEPDPSITKLAEQYAKENGTNVSLTNDPLEAARGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAEVAASDWTFLHCLPRKPEEVDDEVFYSPQSLVFPEAENRKWTIMAVMVSLLTDYSPQLQKPKF
What is the function of this protein?
Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline.  The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion.
What are the official names of this protein?
Ornithine transcarbamylase, mitochondrial, OTCase, Ornithine carbamoyltransferase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TPM02_PERAM
Sequence: MDAIKKKMQAMKLEKDNAMDRALLCEQQARDANLRAEKAEEEARSLQKKIQQIENDLDQTMEQLMQVNAKLDEKDKALQNAESEVAALNRRIQLLEEDLERSEERLATATAKLAEASQAADESERARKILESKGLADEERMDALENQLKEARFMAEEADKKYDEVARKLAMVEADLERAEERAESGESKIVELEEELRVVGNNLKSLEVSEEKANLREEEYKQQIKTLTTRLKEAEARAEFAERSVQKLQKEVDRLEDELVHEKEKYKFICDDLDMTFTELIGI
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin Per a 7.0102, Major allergen Per a 7.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: BXA5_BOMMO
Sequence: MKLLLAIALMLTTVMWASTQQPQTVHTYCGHHLARTLADLCWEAGVDKRSDAQFASYGSAWLMPYSEGRDQRGIVDECCLRPCSVDVLLSYC
What is the function of this protein?
Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects.
What are the official names of this protein?
Bombyxin A-5, BBX-A5, 4K-prothoracicotropic hormone, 4K-PTTH.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLR71_PLAVT
Sequence: MRPTGWRWPVLSLLLVLLPFQAAGPPRPRAAWTRIVSFLTCALTALAASWMTATRTLSNEITHCLTLTRLFRRYTIVNSWLLDRSLREAVLPSKTVTRMAIDQLWWPRKYTSTNGTIWCWGGGPSGISCRWIRINTCASCRTADPSGNARVYTVARPQPPTCCSNGRPRPLFRTFRYRTLPYLINPKRANNGAGPRQRFRNVYPPRLATVSLGRDGNGPVRGISSSPTRLTRPRMGGNTLRVSRTFGPVPCIVPEAKPWTPRVKRRCPLGATSRRLRPQARRGNVCACVVENGYGTAGYVPAAARCRLVRPPVRSTTRFST
What is the function of this protein?
Secreted effector that partially suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 71.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: SYP_STRU0
Sequence: MKQSKMLIPTLREMPSDAQVISHALMMRAGYVRQVSAGIYAYLPLANRTIEKLKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGDDLYKLKNRESSDFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQAKYRDEKRPRNGLLRTREFIMKDGYSFHQNYEDLDVTYEDYRKAYEAIFTRSGLEFKGIIGDGGAMGGKDSQEFMAITPERTDLNRWLVLDKSIPSLSDIPEDVLEEIKKELASWLISGEDTIAYSSESSYAANLEMASNAFSPTTKVAVAEDLKEVATPDCKTIDQVADFLNISAETTIKTLLFIADEKPVVALLVGNDQVNDVKLKNYLGADFLDPATEEEAFQVFGAHFGSLGPVNLPDSVRIIADRNVQNLANAVSGANKDGFHLTGVNPERDFKAEFVDIREVKEGEASPDGHGHLQFARGIEVGHIFKLGTRYSDSLGANILDENGKSIPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGEYRYSWGINFPKELAPFDIHLITVNTKDEEAQTLTDKLEKELMTKGYEVLTDDRNERVGSKFSDSDLIGLPIRITVGKKASEGIVEIKIKASGDSIEVNAENVIETLEILTKDH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPQ_PROMH
Sequence: MEKLLSLYQEHIKTLQNRTRDALSRHHLDNVLIHSGEPIGVFLDDSDYPFKVNAHFKAWVPVTDVPHCWLLVDGVNKPKFWFYSPVDYWHSVEALPSSYWTHEIELIHLKNVDDIQKELAPFINKNTAYIGPNTQRADSLGVSLDNVNNQSLLNYYHYYRAYKTGYELACMREAQKMAVNGHIAAREAFQAELSEFDINMAYLMATGHRDTDVPYGNIVALNEHAAVLHYTKLDHQSPDEYRSFLIDAGAEYNGYAADITRTYSAKENHEFTALVKDMNDAQQALIATMKAGVRYSEYHIQMHQRIAGLLHKYGIVKGISEEEMVSEGLTTPFLPHGLGHALGLQVHDAGGFMQDDKGTHLAAPAMYPFLRCTRIVEPGMVLTIEPGFYFIDSLLAPWREGKYRSHFDWHLIEHFKPFGGIRIEDNIIIHDNKIENMTRDLHLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: ZG64_XENLA
Sequence: PSGKQYECPECGKTFKYKNSLTIHQRGHTEEKPFMCTQCGKCFRQKKALRRHQFIHTGEKPYVCTECEKRFLEKSQLILHQRGHTGEKPFTCTECGESFRHKQVLMRHQFIHTGEKPYECTQCGEGFLLKSKLIHHQRGHTGEKPFMCTECGKGFRQKQVLIEHQFIHTGEKPLMCTDCGKHFRQKHVLRLHKLSH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Gastrula zinc finger protein XlCGF64.1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TYRA_STAEQ
Sequence: MRNILFVGLGLIGGSLASNLKYHYSNFNILAYDSDYTQLDEALSIGIIDQKVNDYATAVEIADIIIFATPVEQTIKYLSELTNYNTKTHLIVTDTGSTKLTIQSFEKELLKHDIHLISGHPMAGSHKSGVLNAKKHLFENAYYILVFNEIENNEAATYLKKLLKPTLAKFIVTHANEHDFVTGIVSHVPHIIASILVHLSANHVKDHSLIEKLAAGGFRDITRIASSNAQMWKDITLNNQNHILSLLNEIKEQITGIENLIREQNSNSIYDFFVKAKDYRDQLPVKQHGAISTAYDLYVDIPDKPGMISQITNIISSHNISIINLKILEVREDIYGALQISFKSPEDRENAIKALANFDTYY
What are the official names of this protein?
Prephenate dehydrogenase, PDH.
What is the protein family that this protein belongs to?
Belongs to the prephenate/arogenate dehydrogenase family.
Protein: SCOT_DROME
Sequence: MLCRLVGNRSLGARYTASIKAIACYSTSGKQRNGKIYESAIDAVADVQDGAQILFGGFGICGIPEKMINALKQKGVKNITGVSNNGGVDDTGLGVLIKQKQVSKVIGSYVGENTELVRQYLEGELAVELTPQGTLAEKIRAGGAGIPAFYTPTGYATLVQEGGAPIKYSKDGKVEISSEKKPVKEFNGKNYVMEESIFADFAFVKAQKADPLGNLVFNKAARNFNAPMCRAAKITVAEVEEIVPIGALSPDEIHVPGIYINRIFKGTNYNKRVERLRITEPKDPSKPAPPPNPAQVLRERIARRVALEFHDGMYANLGIGIPVLSSNYIPKGMNVMLQSENGILGLGPFPTKDKVDPDLINAGKESVTVVPGASYFGSDDSFAMIRGGHVDITILGAMEVSATGDLANWMIPGKLVKGMGGAMDLVAAPGTKVIITMEHNARDGSPKILDTCSLPLTGKGVIDMIISEKAVFTVEKGVGLTLIEVAEGYTVDDIIASTGAKFTVSPNLKKMGQIPV
What is the function of this protein?
Key enzyme for ketone body catabolism (PubMed:24100554).  Transfers the CoA moiety from succinate to acetoacetate (PubMed:24100554).  Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity).
What are the official names of this protein?
Succinyl-CoA:3-ketoacid-coenzyme A transferase, mitochondrial, 3-oxoacid CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LRC53_MACFA
Sequence: MLQLVAACPESCVVCTKDVTLCHQLTYIVAAPMTTRVLIITDGYLSSIESTNLSLLFNLALLSLSRNGIEDVQEDALDGLTMLRTLLLEHNQISSSSLTDHTFSKLHSLQVLVLSNNALRTLRGSWFRNTRGLTRLQLDGNQITNLTDSSFGGTNLHSLRHLDLSNNFISYIGKDAFRPLPQLQEVDLSRNRLAHMPDVFTPLKQLIHLSLDKNQWSCTCDLHPLARFLRNYIKSSAHTLRNAKDLNCQPSTAAVAAAQSVLRLSETNCDPKAPNFTLVLKDRSPLLPGQDVALLTVLGFAGAVGLTCLGLVVFNWKLQQGKANEHTSENLCCRTFDEPLCAHGARNYHTKGYCNCHLTQENEIKVMSIVGSRKEMPLLQENSHQATSASESTTLDGSFRNLKKKDHGVGSTLFCQDGRLLHSRCSQSPGNTTAFNEAGLLTTYNSRKVQKLRNLESGEVLPQTLPHHIIRTEDISSDTFRRRYAIPTSALAGESLEKHLTNESCLHTLN
What are the official names of this protein?
Leucine-rich repeat-containing protein 53.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CH60_BIFLO
Sequence: MAKIISYDEEARQGMLEGLDKLANTVKVTLGPKGRNVVLDKTYGAPTITNDGVSIAKEIDLEDPYERIGAELVKEVAKKTDDVAGDGTTTATVLAQSLVHEGLKNVVAGSNPIALRRGIEKATEVIVKELVAAAKDVETKDQIAATATISAADPEVGEKIAEALDKVGQDGVVTVEDNNRFGLDLDFTEGMRFDKGYIAPYFVTNADDQTAVLEDPYILLTSGKVSSQQDIVHVAELVMKTGKPLLIIAEDVDGEALPTLILNNIRGTFKSCAVKAPGFGDRRKAMLQDMAILTGAQVVSDELGLKLESVDTSVLGHAKKVIVSKDETTIVQGAGSKEDIDARVAQIRAEIENTDSDYDREKLQERLAKLAGGVAVIKVGAATEVEAKERKHRIEDAVRNAKAAIEEGLLPGGGVALVQAAAKAEKTEAVTSLTGEEATGAAIVFRAIEAPIKQIAENAGVSGDVVINTVRSLPDGEGFNAATDTYEDLLAAGVTDPVKVTRSALQNAASIAGLFLTTEAVVANKPEPKSAAPAAGADMGY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI_THEFM
Sequence: MKYSELAGLYRRLEKTTLKTLKTRFVADFLKNVPDELLEIVPYLILGKVFPDWDERELGVGEKLLIKAVSIATGVPEGEIENSIKDTGDLGESIALAVKKKKQKSFFSQPLTIKRVYDTFVKVAESQGEGSQDRKMKYLANLFMDAQPEEAKYIARTVLGTMRTGVAEGILRDAIAEAFKVKAELVERAYMLTSDFGYVTKVAKLEGNEGLSKVRIQVGKPVRPMLAQNAASVKDALLEMGGEAAFEIKYDGARVQVHKDGDRVVIYSRRLENVTRSIPEIVEAVRSQLRPEKAIVEGELVAVGDGGKPRPFQYVLRRFRRKYNIEEMIERIPLELNLFDVLYVDGESLVDTPFMERRKRLEEAVEESERIKLAQQLVTKKAEEAEEFYRRALELGHEGLMAKRLDSVYEPGNRGKKWLKIKPTMEDLDLVIIGAEWGEGRRAHLLGSFLVAAYDQHRGEFVPVGKVGSGFTDEDLAEFTKMLKPLIVREEGKYVEIEPRVVIQVTYQEIQKSPKYESGFALRFPRYVALREDKSPEEADTIERISELYGLQERFKAKR
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.  Shows high activity with either ATP or NAD(+).
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP/NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: CYB_DIPVE
Sequence: MTILRKTHPLMKMVNHAFIDLPTPANISGWWNFGSLLGLCLIIQIASGLFLAMHYTPDTLTAFSSVTHICRDVNYGWLIRYMHANGASLFFICLYLHIGRGIYYGSYSYTETWNIGIILLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLNRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSDCDKIPFHPYYTTKDFLGMVLLLAFFFTMVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALIMSILVLALLPHIQTSKQRSLMFRPISQFLFWLLVADVLALTWIGGQPVEPPFIIIGQIASLLYFTIILILMPIAGIIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VG24_BPML5
Sequence: MTNVFTIDAFREEVKKKYAPVLIGLSDDVTVELKPLLKLGQKAREAVVEVFKEFADIPDLEEDDDDELVDEYSLQVCDIIAKAFRLIATKPKKLIAALDEEPDPRIRAELYAAVLNTWKRETQLGEAAPSPS
What is the function of this protein?
Promotes tail assembly by creating a scaffold for the tail tube proteins.  The tail assembly proteins Gp24 and Gp25 would wrap the linear tape measure protein to create a tail assembly scaffold.  It would allow polymerization of tail tube protein during which Gp24 and Gp25 are released and therefore are absent from the mature virion.  The tail assembly protein Gp25 is produced by a rare -1 ribosomal frameshift.  The ratio Gp24/Gp25 is important for proper tail assembly.
What are the official names of this protein?
Tail assembly protein Gp24, Gene product 24, Gp24, Minor tail protein Gp24.
What is the protein family that this protein belongs to?
Belongs to the L5likevirus tail assembly protein family.
Protein: CHRC1_ONCHC
Sequence: MTSIAFWNAFTVNPFPAAARRSPPPLTPFTSGALSPARKPRILEISHPRTLPSFRVQAIAEDEWESEKKALKGVVGSVALAEDETTGADLVVSDLKKKLIDQLFGTDRGLKATSETRAEVNELITQLEAKNPNPAPTEALSLLNGRWILAYTSFAGLFPLLGAESLQQLLKVDEISQTIDSEGFTVQNSVRFVGPFSSTSVTTNAKFEVRSPKRVQIKFEEGIIGTPQLTDSIVIPDKFEFFGQNIDLSPFKGVISSLQDTASSVAKTISSQPPIKFPISNSNAQSWLLTTYLDDELRISRADGGSVFVLIKEGSPLLT
What is the function of this protein?
May be involved in carotenoid sequestration within chromoplasts.
What are the official names of this protein?
Chromoplast-specific carotenoid-associated protein C1, chromoplastic, OgCHRC1, Fibrillin-like protein 1, Plastid lipid-associated protein CHRC1.
What is the protein family that this protein belongs to?
Belongs to the PAP/fibrillin family.
What are the subcellular locations of this protein?
Plastid, chromoplast.
Protein: NUOD_ORITB
Sequence: MALKKRSKHSKKFKLNLGPQHPATHGVLRLILEMDGEIVERADPHIGLLHRGTEKLIEYKTYLQAIPYFDRLDYVSPMCQEHAFALAIEHLLKCEVPLRAQYIRVMFSELTRILNHTLNIATQALDVGATTPLLWMFEEREKIMEFYERVSGSRLHANYFRPGGVAQDLPEGLIENIVDFCEQFPCKIADLETLLTDNRIWKQRTVDIGIVSKQQAMDWGFSGVMLRGSGIAWDLRKSQPYDQYANLDFDVAIGKNGDCYDRYLIRIEEMYQSIKIIKQCIQKMPVGEIKTQDPSISPPKRSEIKKSMEALINHFKLYSEGYNVPAGEVYAAVEAPKGEFGVYLYSDGTNRPYRCRIKAPGFAHLQGLDFMARGHSLSDIITIIATLDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KITH_STAEQ
Sequence: MYETYHSGWIETITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNGNEIEAINISTAQEILNHKLEEVNVIGIDEVQFFEDDIVNIVEKLAENGHRVIVAGLDMDFRGEPFKPMPKLLAVSEHITKLQAVCSVCGSPSSRTQRLINGEPAKVDDPIILVGANESYEPRCRAHHIVAPSENEKEEM
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRK_BACC4
Sequence: MMQKQNMIVVNQKEIAKNIYELVLQGTLVQQMNEPGQFVHIKVAEGIAPLLRRPISICNVDQEKNEFTMLYRAEGQGTKTLATRKQGEMVDVLGPLGHGFPLEEAEAGQTALLVGGGIGVPPLYELSQRLVAKGVRVIHILGFQTKDVVFYEEKFAELGDTYVATVDGTHGTKGFVTDVIDNYGIDFDILYSCGPLAMLRALEGRYKEKKAYISLEERMGCGIGACFACVCHLQEDPSGHSYKKVCSDGPVFPIGEVVL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.