PharMolix/UniProtQA huggingface dataset:
Protein: ENO_MYCBP
Sequence: MPIIEQVGAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGVQKAVQAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRYVGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGAEVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRPGADVALALDAAATEFFTDGTGYVFEGTTRTADQMTEFYAGLLGAYPLVSIEDPLSEDDWDGWAALTASIGDRVQIVGDDIFVTNPERLEEGIERGVANALLVKVNQIGTLTETLDAVTLAHHGGYRTMISHRSGETEDTMIADLAVAIGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFACETK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SYM_RUTMC
Sequence: MTSRKILVTSALPYANGEIHLGHLLEYIQADIWVRFQKMMGNECYYVCADDTHGTPIMLKSDELGITPETLIKGVSERHQADFKEFSIGFSKYHSTHSQENKDISANIYHKLNDAGFIKTRIISQAFDPEKQMFLPDRFIKGDCPKCGANDQYGDNCEICGVTYSPTELKNAKSIISDATPIAKDSEHYFFDLPQFETQLKAWIKEGHLQDEVSNKLSEWFEQGLQQWDISRDAPYFGFQIPDVEGKYFYVWLDAPIGYMASFKKLCDEQGLDFDEYFNKDSNTELYHFIGKDIVYFHALFWPAILMGSNYRTPSAIFVHGFLTVNGQKMSKSRGTFIQARTYLNHLNPECLRYYYAYKLSAKIDDIDLNLTDFKQRVNSDLVGKVVNIASRSTGFLVKKFNKTLSDYAIDPELYHEFVACGDIIKKHYEARNYNQAMREIMKLADKANQYIDEHKPWQLVKKDTKQVHDVTSLAINLFRVLMTYLKPVLPVMAKQAEMFLNIDAFNWQDLKRPLTKHQINTFKPLMSRIEDEKIEQVIEASKQNMQVVA
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOCD_SALSV
Sequence: MVNNMTDLTAQDAAWSTRDHLDDPVIGELRNRFGPDAFTVQATRTGIPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHLISIERNRDIMLKVALSENDLRVPTFTKLFPNANWYERETWEMFGIDIEGHPHLTRIMMPQTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEDWGMKRGTDNEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLDSYEKAALRNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKWRPYSGYENFDFEVPVGGGVSDCYTRVMLKVEELRQSLRILQQCLDNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPAQESFQMVEATKGINSYYLTSDGSTMSYRTRVRTPSFAHLQQIPSAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRXB_ALIFS
Sequence: MNVKHSKLLILGSGPAGYTAAVYAARANLNPVMITGMQQGGQLTN
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRGBP_MOUSE
Sequence: MGEAEVGGTGAPGDKGPGEAAPSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQNIGRQVPSKVIWDHLSTMYDMQALHESEILPFPNPERNFVLPDEIIQEVREGKVVIEEEMKEEMKEDVDPHSGADDVFSSSGSLGKALEKSSKDKEKNSSDLGCKEGADKRKRSRVTDKVLTANSNPSSPSAAKRRRT
What is the function of this protein?
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A.  This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription.  This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair.  NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
What are the official names of this protein?
MRG/MORF4L-binding protein, MRG-binding protein.
What is the protein family that this protein belongs to?
Belongs to the EAF7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HUTU_KLEAE
Sequence: MSQSKYRQL
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALB2_CHICK
Sequence: MAGQRAPHLHLAELSASQFLDVWRHFDADGNGYIEGKELENFFQELESARKGTGVDSKRDSLGDKMKEFMHKYDKNADGKIEMAELAQILPTEENFLLCFRQHVGSSSEFMEAWRRYDTDRSGYIEANELKGFLSDLLKKANRPYDEAKLQEYTQTILRMFDMNGDGKLGLSEMSRLLPVQENFLLKFQGMKLSSEEFNAIFAFYDKDGSGFIDEHELDALLKDLYEKNKKEMSIQQLTNYRRSIMNLSDGGKLYRKELEVVLCSEPPL
What is the function of this protein?
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
What are the official names of this protein?
Calretinin, CR.
What is the protein family that this protein belongs to?
Belongs to the calbindin family.
Protein: VF030_IIV6
Sequence: MELNKNYKLNKQQSRALTLMCQDKNIFITAPAGAGKTLLINHYCDYVRQHEPFKKIAITSTTGVSAILIGGSTLHSYLGIGLGDGTIEDLVQRIKKASKGIKERVWKELTTLIIDEVSMLNPVLFDKLEKIARIIRGSDLPFGGIQLILSGDLLQLPVVKGGGTGNKNDHNMEFVTDANSWKKCIGNNIVLLTEIMRQKDFHFKEILLKIRVGNIDQQVRSVLSQHMKKEEKLKKEEIQPTRLFCLKKYVQDLNDSELKKLEDSGKKFINFNALIKKYSEEAVLTNKGRSRCTDLQFKFLSDRFVKDSTTPQHLRVCEGAQVMLTYNIDQLSGLVNGSRGVIIGFTEMKFPIVRFKNHKRNNLTPKLNKTNEDIKSDSTSQPQGFPEGNRRVMENPETKVSKTDDEEMNDTLELEVRPQTWEICNDFGKKIGYFKQIPLKIAYALTIHSCQGSTLDSAEVDLSDTFEHGQVYTALSRTRDLNSLVIKNLCFDSIKCHPRALQFYDDIKSMQDAISEIENSLSELDFDDDF
What are the official names of this protein?
Uncharacterized protein 030L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 030L family.
Protein: MOBA_TRIV2
Sequence: MNNLTAIVLAGGQSSRMGQDKALITVQGVPLLQFVCNIAASCAEIVYIVTPWPERYEHLVLPRCQFIPEAGTQGPLIGFAQGLAQVKSEWVLLLACDLPKLRVEVLQEWAANLDSVPEEAIATLPHHAKGWEPLCGFYRRRCSPPLLEFIHQGGRSFQQWLQHHSVQVLALPTPEILFNCNTPEDLAVIQGEFDDLSPNPSPTRRGA
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2275_RENSM
Sequence: MTDSTPEAGAEGEFTPVKPQESELLVVTGMSGAGRSTAANALEDHGWYVVENLPPQMLTTLADLVARTPNSLPKLAVVVDVRGKAFFADIRDSLNTLAASGISYRVLFLDASDNTLVRRFEQGRRPHPLQGDGRMLDGIAAEREILALLRDSADVVVDTTSLNVHELANQVTGLFSDSGPVVLRLTVMSFGFKYGLPVDANYVADVRFLPNPHWVPALRPHTGLDQDVSDFVLIENDANEFVTRYVRALGPVLEGYRRENKHYATIAVGCTGGKHRSVAVSVELAKRLAQLPRVTVSTKHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein RSal33209_2275.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: ARNT_PSEAB
Sequence: MSRRQTWSLLLIAFGLFYLVPLSNHGLWIPDETRYAQISQAMLLGGDWVSPHFLGLRYFEKPVAGYWMIALGQAVFGENLFGVRIASVVATALSVLLAYLLARRLWRDPRTSLACALLYASFGLIAGQSGYANLDPQFTFWVNLSLVALWYALDAGSRRARLLGWILLGLACGMGFLTKGFLAWLLPVLVALPYMLWQRRWRELLGYGALAVLAALLVCLPWALAVHAREADYWRFFFWHEHIRRFAGEDAQHSRPWWFYLPLLVVACLPWSGLLPSALRQAWHERRQAPVVFLALWLLLPLAFFSLSRGKLPTYIMPCLLPLALLMGHALVQRLRLGNSVALRGNGLLNLGLALLALAALAYLQLRKPVYQEEPFELFLVLLVIGAWAAAGLAQWRYPLRAWAAPLLASWVLIALLPAAMPNHVVQNKTPDLFVAEHLDELTGARHLLSNDLGAASALAWRLRRSDVTLYDTRGELKYGLSYPEHSQRSVPLADIRQWLWRARQDGSVAVLLRINSASDRYQLALLPGDGERYRNGNLVLAILPQVRP
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYP_PLAF7
Sequence: MNNNTNGEIIIPQEYLEKSECLFKELKELNINFKEVKHGLAATIKDLLEMNLENSTNILKNLFLKDKKKNYFLICTLNNKTVDLKNLSNILKTNNLRFVDENNLNNILNIQPGCLSPLAIKNDKENIVKLYFDEEIKNMQEVIIHPLHNYSSLYIKTQDVIKFCESFNHAPEYVQIKEDTTSKARVDKKEDVQEEMAKNEELQNNNNNNKNNSNSNNNNNNNNNHIKDTILKGKLLSNNEVEDNKSKDSNILGITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKNHIEGFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNQTNSETTLSGAMKPLCIPLDQPPMPPNMKCFWSGKPAKRWCLFGRSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro) (PubMed:25817387, PubMed:27798837).  Functions in trans to edit the amino acid moiety from incorrectly charged Ala-tRNA(Pro) (PubMed:14663147).  Has no activity on correctly charged Pro-tRNA(Pro) or Ala-tRNA(Ala) (PubMed:14663147).
What are the official names of this protein?
Proline--tRNA ligase, PfPRS, Prolyl-tRNA synthetase, PfProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_BACAN
Sequence: MRRTLYRLMIELTNGRFTSYTLRKFAQSRLSSIIIPSYAKVFQINQDEMEKGLKEYRTLHELFTRKLKEGKRSIDTDASSIVSPVDGVFADHGPIEDTKTFDIKGKRYSIVDMLGNEERAQRYAGGTYMVIYLSPSHYHRIHSPLSGSVTERFVLGRKSYPVNAAGMEYGKEPLSKNYRSVTEVNSDGEHMALVKVGAMFVNSIELLHERDTVQKGEEMAYFTFGSTVVLLFEKDMIEVVQELKSGQELRLGEKIATRLAHK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AINX_HUMAN
Sequence: MSFGSEHYLCSSSSYRKVFGDGSRLSARLSGAGGAGGFRSQSLSRSNVASSAACSSASSLGLGLAYRRPPASDGLDLSQAAARTNEYKIIRTNEKEQLQGLNDRFAVFIEKVHQLETQNRALEAELAALRQRHAEPSRVGELFQRELRDLRAQLEEASSARSQALLERDGLAEEVQRLRARCEEESRGREGAERALKAQQRDVDGATLARLDLEKKVESLLDELAFVRQVHDEEVAELLATLQASSQAAAEVDVTVAKPDLTSALREIRAQYESLAAKNLQSAEEWYKSKFANLNEQAARSTEAIRASREEIHEYRRQLQARTIEIEGLRGANESLERQILELEERHSAEVAGYQDSIGQLENDLRNTKSEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTSGLSISGLNPLPNPSYLLPPRILSATTSKVSSTGLSLKKEEEEEEASKVASKKTSQIGESFEEILEETVISTKKTEKSNIEETTISSQKI
What is the function of this protein?
Class-IV neuronal intermediate filament that is able to self-assemble.  It is involved in the morphogenesis of neurons.  It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges.  May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).
What are the official names of this protein?
Alpha-internexin, Alpha-Inx, 66 kDa neurofilament protein, NF-66, Neurofilament-66, Neurofilament 5.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: MURA_GLAP5
Sequence: MEKFRVHGPFTLSGTVDISGAKNAALPILFAAILAEEPVILTNVPNLKDVETTVKILRKLGVVVERAENNAVHIDASKIDHYVAPYELVKTMRASIWALAPLVARFHQGQVSLPGGCTIGARPVDMHIAGLEKMGATITLDEGYVKAEVNGRLTGARILMDKVSVGATLSVMMAATLAKGTTTIENAAREPEIVDTAIFLNKMGAKITGAGTDTITIEGVERLGGCEHHIVPDRIETGTFLVAAAISGGRITCRGTKADTLDAVIEKLREAGMQVDVTENSITLDSLGMRPKAVNIRTMPHPGFPTDMQAQFTLLNVVANGTSKITETIFENRFMHIPELIRMGAKAEIEGNTAICHGVENLSGAEVMATDLRASISLVLAGCIANGQTIVDRIYHIDRGYEHIEDKLQKLGARIERFNAPFEE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRB_RICPR
Sequence: MSVIEEKCNESSYSADSIKVLKGLEAVRKRPGMYIGDVGDGSGLHHMIYEVVDNSIDEALAGYCDLVQVTLNKNGSVTVSDNGRGIPVEIHEEEGISAAEVIMTQLHAGGKFDQQSYKISGGLHGVGVSVVNALSEWLELRIWRNNKEYFIRFNNGITEAPLSIVKENIDKKGTEVTFFPSVGTFTNIEFDFVTIEHRLRELAFLNSGVKILLVDNRFEEVKKVEFYYTGGIEAYVQYIDRAKHAIHPCIVVNTVHVESGISLELALHWNDSYHENILCFTNNIRQRDGGTHLSAFKSAITRVITSYLDTTGLNKKTKHDFSGEDTREGICCVLSVKVPDPKFSSQTKDKLVSSEVRPVVENAVYTKVLEWFEEHPTEAKAIIAKIMEAANAREAARKARELTRRKSALEVSNLPGKLADCHAKDPAISELFIVEGDSAGGTAKQGRDSKIQAILPLRGKILNVERARFDKMLGSDQIGTLITALGISVEREFSLEKLRYHKVIIMTDADVDGSHIRALLLTFFYRHMPELINKGYLYIAQPPLYKVKSGASELYLKNEKALQNYLIKSTINDTYLILDGQEQLVGENLEDLINKVVKFNNLLDHVSKKFNRSITEILAINDLFNKKIFEPESSARLQKALDILNNLEESPDKTNLQVLKHENKIEFFHFSRGLKETKILLKEQLELFEFVEISQFALSIFDIFSKRLKLIVKSKAFDILTPSQLLNTIIECGKKGITIQRFKGLGEMNSDQLWETTLDPTKRTLLQVRVAEVDEAEGIFSTLMGDVVEPRRLFIQANALNVMNLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANR53_MOUSE
Sequence: MRRPSRRRSKASTPPRSHTTPRRTGPSDSRRRPGTKEQPRPSVQGGTRQAEHDLKVSSPNSESSQYSTSELWSHKVIANYSELFAASVGNVDWLRFCVNPERKEIIVDDKGFTAIHFAAQKCQLSCLKVLIEEYKYPVDLPTNKGQTPLHLVIHKNNKSDILPCIDYLLKKGAAINSQTYNGSTPLHLASCNGLLGCIKLLVQSGANVHARDATGFKPIDYCRLWNHRTCARFLKDVMWKHDKKVLAQEMEKLRTLKEKLTILEYHYLVEYQKEHQILREAHFRKWLQNKVLAQTLGSADSKQKAGVQPWSLASNTLRCPITESLHYPSVEAQLKNLPSPVVPPKPIYKQTTISRPKLWNYSANPARSPITNIGHPQNIRLGVHPEPYKEHDFRRFLEVTRNKHGGACLRTVDRQLVTPVPQLPFEMMVRVLYPGTQPYRMKVPQGLYPRDILKVPEKRHVGDTCSNTMAMTLRETFDKPFLDSLEVCRTRVAPPSK
What is the function of this protein?
Required for normal progression through mitosis.  Involved in chromosome alignment and cytokinesis via regulation of microtubules polymerization.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 53.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes at the spindle around the centrosome at prophase and prometaphase and at the spindle poles at metaphase and anaphase.
Protein: ADX_CHICK
Sequence: CSAVAVRTLRPLSLSARAACSSEDKITVHFINRDGDKLTAKGKPGDSLLDVVVENNLDIDGFGACEGTLACSTCHLIFEDHIFEKLDAITDEEMDMLDLAYGLTETSRLGCQICLKKSMDNMTVRVPEAVADARQSVDLSKNS
What is the function of this protein?
Essential for the synthesis of various steroid hormones.  Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis.  Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage.  Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons.
What are the official names of this protein?
Adrenodoxin, mitochondrial, Adrenal ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL5_METMJ
Sequence: MTAMKDIYIDKVVVHMGVGESGERLVKAEDLVKQITGQKPVRTIAKRTQPAFGIRKGAPIGCKVTLRRENAEKFITTALDIIERRLAPSQFDRTGNVSFGIEEHTDFPGMSYDPTIGIYGMDVNVVLEYKGARIARRSVERRKLPADQKVNKEEAIAFMCENYRVEV
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: YPZ6_METTF
Sequence: MRQIAEMRKEVSQHGFDVRMMEVPGMKVAIAGDGEVNYLFMLLPFRDKFKLKKRDVWLFKKLSYKFQARPFMVTFDKMLSFYPLHALEEAGEHFELDIRNSRGLMFSFDTIVSEQLQQRLVV
What are the official names of this protein?
Uncharacterized protein ORF6'.
Protein: SHDAG_HDV27
Sequence: MSRSESKESRKGREESLEKWVNSRKKVEELERELRKEKKKIKRLEDQNPWLGNIKGILGKKDKDGEGAPPAKRARTDQMEVDSGPRKRPLRGGFTDKERQDHRRRKALENKKKQLAGGGKNLSREEEEELKRLTEEDERRERRVAGPPTGGVNPLEGGQRGAPGGGFVPSMQGVPESPFSRHGEGLDTRGDRGFP
What is the function of this protein?
Promotes both transcription and replication of genomic RNA.  Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA.  RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome.
What are the official names of this protein?
Small delta antigen, S-HDAg, p24.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LIP1_STAAM
Sequence: MKSQNKYSIRKFSVGASSILIATLLFLSGGQAQAAEKQVNMGNSQEDTVTAQSIGDQQTRENANYQRENGVDEQQHTENLTKNLHNDKTISEENHRKTDDLNKDQLKDDKNSSLNNKNIQRDTTKNNNANPSDVNQGLEQAINDGKQSKVASQQQSKEVDNSQDSNANNNLPSQSLTKEAPSLNKSDQTSQREIVNETEIEKVQPQQNNQANDKITNHNFNNEQEVKPQKDEKTLSVSDLKNNQKSPVEPTKDNDKKNGLNLLKSSAVATLPNKGTKELTAKAKDDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQDLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGIYKDWKPGQKVHLVGHSMGGQTIRQLEELLRNGNREEIEYQKKHGGEISPLFKGNNDNMISSITTLGTPHNGTHASDLAGNEALVRQIVFDIGKMFGNKNSRVDFGLAQWGLKQKPNESYIDYVKRVKQSNLWKSKDNGFYDLTREGATDLNRKTSLNPNIVYKTYTGEATHKALNSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTNATDKIQKGIWQVTPTKHDWDHVDFVGQDSSDTVRTREELQDFWHHLADDLVKTEKVTDTKQA
What are the official names of this protein?
Lipase 1, Glycerol ester hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOE_STAAW
Sequence: MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: RCNR_SHISS
Sequence: MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAAIRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK
What is the function of this protein?
Repressor of rcnA expression.  Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt.  In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity).
What are the official names of this protein?
Transcriptional repressor RcnR.
What is the protein family that this protein belongs to?
Belongs to the FrmR/RcnR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_AZOSB
Sequence: MSAISQERLLQVLLAPQISEKATYVADKNEQVVFKVATSATKPEVKAAVELLFKVEVKSVQISNVKGKSKRFGKMMGRRKDWKKAFVCLKPGQEINFVAGE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MURA_SHEPC
Sequence: MDKLTIQASPPLAGDVIISGAKNAALPILMAGVLAETDFVVSNVPNLRDVSTSCKLLRCLGAEVTELGDGQIRISTTNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAAALADGETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCEYRVMPDRIETGSFLVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMEGKRPKAVNIKTAPYPGFPTDMQAQFCVLNALAQGTATITETIFENRFMHVPELIRMGATMELEGNTCIIQGIESLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRGYEHIEQKFQGLGAHVERVQ
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_CITBB
Sequence: MAKVDVVERVTEIIAEVGAPLGIELVDLEYKREGRDMVVRVFLEKREGGINLDDCADVSRQLSDILDVEDFMPERYTLEVSSPGICRPLKKVADYERFLGHLIKVKTFEMLADEAGNKRKTFTGKLTGIADGVIGIDLTEGQKARVPLDKVAKANLEFEF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.