PharMolix/UniProtQA huggingface dataset:
Protein: RLME_ACIBY
Sequence: MATRITNQKLSKSSRAWMREHLDDPFVKKAQKEGYRARAAYKLLEIQEKYKLIKPGMTVVDLGAAPGSWSQIAGKLVGSKGLVIASDILPMDALPDVTFLQGDFREEAVFEKLLNILNGRQVDIVISDMAPNTSGNRAVDQPRQIYLCELALDFAQKVLGPNGQFVVKVFQGAGFDEFRKQVVDSFDVLKTAKPAASRARSKEVFLVGQGRKKALQ
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLB1_YEAST
Sequence: MKLQSLLVSAAVLTSLTENVNAWSPNNSYVPANVTCDDDINLVREASGLSDNETEWLKKRDAYTKEALHSFLNRATSNFSDTSLLSTLFGSNSSNMPKIAVACSGGGYRAMLSGAGMLAAMDNRTDGANEHGLGGLLQGATYLAGLSGGNWLTSTLAWNNWTSVQAIVDNTTESNSIWDISHSILTPDGINIFKTGSRWDDISDDVQDKKDAGFNISLADVWGRALAYNFWPSLHRGGVGYTWSTLREADVFKNGEMPFPITVADGRYPGTTVINLNATLFEFNPFEMGSWDPTLNAFTDVKYLGTNVTNGKPVNKGQCIAGFDNTGFITATSSTLFNQFLLRLNSTDLPSFIANLATDFLEDLSDNSDDIAIYAPNPFKEANFLQKNATSSIIESEYLFLVDGGEDNQNIPLVPLLQKERELDVIFALDNSADTDDYWPDGASLVNTYQRQFGSQGLNLSFPYVPDVNTFVNLGLNKKPTFFGCDARNLTDLEYIPPLIVYIPNSRHSFNGNQSTFKMSYSDSERLGMIKNGFEAATMGNFTDDSDFLGCVGCAIIRRKQQNLNATLPSECSQCFTNYCWNGTIDSRSVSGVGNDDYSSSASLSASAAAASASASASASASASASGSSTHKKNAGNALVNYSNLNTNTFIGVLSVISAVFGLI
What is the function of this protein?
Sequentially removes both fatty acyl groups from diacylglycerophospholipids and therefore has both phospholipase B and lysophospholipase activities.  It also displays transacylase activity.  Substrate preference is phosphatidylserine > phosphatidylinositol >> phosphatidylcholine > phosphatidylethanolamine (PubMed:10497163, PubMed:8051052).  The substrate specificity is pH- and ion-dependent.  In contrast with activities observed at optimum pH 3. 5, the order of substrate preference at pH 5. 5 is phosphatidylcholine = phosphatidylethanolamine >> phosphatidylinositol.  Degrades predominantly phosphatidylcholine and to some extent phosphatidylinositol in vivo (PubMed:15588231).
What are the official names of this protein?
Lysophospholipase 1, Phospholipase B 1.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: HIS1_PELPD
Sequence: MSNMLKFGIPKGSLENATVELFKKSGWQVSISSRSYFPGIDDSEMTCKLIRPQEMGRYVERATIDAGIAGRDWVSENQSDVVEVCEMVYSKVSRRPARWVLVANGDSNVKGPEDLAGATIATELVGFTKRYFSERNIPVNVEFSWGATEAKVVDGLCDAIVEVTETGSTIKANGLRIVCELMESVPVLIANKASWADPWKREKIEQIATLLKSSLAAENMVGLKMNAPGDKVEAITSVLPSLKNATVSHLYNSDWLSIESVMSEKEVRRVIPELIKLGAEGIIEYPLNKII
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFI_STRCO
Sequence: MTTVSVQIPAGWPATEERARAVQDELRARVVLDEPGPPPGTGRVTGVDVAYDDERDVVAAAAVVLDAGTLAVVAEATAVGRISFPYVPGLLAFREIPTVLAALEALPCPPGLVVCDGYGLAHPRRFGLASHLGVLTGLPTIGVAKNPFTFTHDDPDTPRGSTSPLLAGAEEVGRAVRTRDGVKPVFVSVGHRVGLGNACAHTLALTPAYRLPETTRRADALCRAALRDAAYRA
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_MYCVP
Sequence: MAQQAPDREKALELALAQIDKNFGKGSVMRLGEEVRQPIAVIPTGSIALDVALGIGGLPRGRVVEIYGPESSGKTTVALHAVANAQAAGGIAAFIDAEHALDPDYAQKLGVDTDALLVSQPDTGEQALEIADMLIRSGALDILVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLREKIGVMFGSPETTTGGKALKFYASVRMDVRRIETLKDGTDAVGNRTRVKVVKNKVSPPFKQAEFDILYGKGISREGSLIDMGVEHGFIRKSGSWFTYDGEQLGQGKENARNFLLQNVDVANEIEKKIKEKLGIGAQLTDDANDDALPAPVDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIM5_SAISC
Sequence: MASRILGSIKEEVTCPICLELLTEPLSLDCGHSFCQACITANHKESMLHQGERSCPLCRLPYQSENLRPNRHLASIVERLREVMLRPEERQNVDHCARHGEKLLLFCEQDGNIICWLCERSQEHRGHNTFLVEEVAQKYREKLQVALETMRQKQQDAEKLEADVRQEQASWKIQIQNDKTNIMAEFKQLRDILDCEESNELQNLEKEEKNILKRLVQSENDMVLQTQSVRVLISDLERRLQGSVVELLQDVDGVIKRIEKVTLQKPKTFLNEKRRVFRAPDLKRMLQVLKELTEVQRYWAHVTLVPSHPSYTIISEDGRQVRYQKPIRHLLVKVQYFYGVLGSPSITSGKHYWEVDVSNKRAWTLGVCVSLKCTANQSVSGTENYQPKNGYWVIGLRNAGNYRAFQSSFEFRDFLAGSRLTLSPPLIVPLFMTICPNRVGVFLDYEARTISFFNVTSNGFLIYKFSDCHFSYPVFPYFNPMTCELPMTLCSPRS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Restricts infection by simian immunodeficiency virus (SIV-mac)(PubMed:22291694).  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2 (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: NSPS_VIBCH
Sequence: MTNFCNEWVSYSQMIKRFLSLMVLNTVCYQASALELNVYLWEDTIAPSVVEAWHKKTGVSVNLFHFDNDDERSLLMLKSVQLPFDIMVLDNVSAFIFSRQNVFEDLTALPNRANNDPMWLQACGTHAVPYFWGSVGIAYRKSLFDKPPTQWSEVVDIAPAHRGRVGMLKDSVETLLPALYMLNASPITDSIDTLRQAYRLLDAANPHILTYEYVLSYVRSHPQTDNLHMAVSYSGDHYSLNRFFNTQDWDFSVPEGRPYLWVDCMAVNSVSPNTVQAKAFLDFLMKPDIAAINAEYIRAASPNYKARALLPVEHREDLSIYLPEQRLAEGIIDSELSAKNLSLRAKIISSVTYQYEAKP
What is the function of this protein?
Acts as a sensor of norspermidine and enhances biofilm formation.  When complexed to norspermidine, could interact with the periplasmic portion of MbaA to regulate its enzymatic activity.
What are the official names of this protein?
Norspermidine sensor, Norspermidine-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein PotD/PotF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HFQ_DECAR
Sequence: MSNKGQLLQDPFLNALRREHVPVSIYLVNGIKLQGQVESFDQYVVLLKNTVTQMVYKHAISTVVPARPVNLQQEQAAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: NANE_PROMH
Sequence: MALIEKMTKDIQQKGGLIVSCQPVDNSPMDKPDIVAAMAQAAVNAGAVAVRIEGIDNLKATRPLIDVPIIGIVKRDLPDSPVRITPWLNDIEALAAAGADIIAFDGTDRLRPVPVKALLEHVHRLGKLAMADCATFNEGMYCHQLGTEFIGSTMSGYTGGEIPKLPDLQLVTALAEQGCRVIAEGRYNTPMMAARGMQAGAWAVTVGSALTRLEHVCEWFTQALKWQQELDK
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: PTFBC_XANCP
Sequence: MSSSIVVIAAGERSTEAVLAAEALRRAATAAGRSVTIEIRSDQGVLGALPTELTNGAAHVLIVGDADADTARFGDAQLLHLSLGAVLDDPAAAVSQLAATTAPASTSATTDASGAGGKRIVAITSCPTGIAHTFMAAEGLQQAAKKLGYQMRVETQGSVGAQDALTDEEIRAADVVIIAADREVDLARFGGKRLFKSGTKPAINDGPALIQKALAEAGVHGGAAPVAGANATSDAKGNARTGAYKHLMTGVSFMLPFVTAGGLLIALAFALGGIYAGDDAHQGTLAWSLFQIGAKAGFTLMVPALAGYIAYSIADRPGIAPGMIGGLVAANLNAGFLGGIIAGFIAGYGVAALNRYIKLPRNLEGLKPVLILPVLGTLLVGLAMMYVFGQPVADLLAWLTAWLRGMQGSSALLLGLLLGGMMAFDMGGPVNKAAYAFSTGLIASQVYTPMAAAMVAGMTPPLGIALATWVFRNRFTVEERGSATAAGVLGLAFVTEGAIPYAARDPLRTIPALVIGSAVAGAISMTAGAELKAPHGGIFVLLIPNAVTHLLNYVLALVVGVVVTAVALRLLKKPVADVIA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FruAB PTS system is involved in fructose transport.
What are the official names of this protein?
PTS system fructose-specific EIIB'BC component, EIIB'BC-Fru.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYY_MYCMS
Sequence: MKNSILEELKWRGLIKQITNESKILDAQNNNDAVYCGFDPTADSLHVGHLMMIITLKRFADYNFKPIALIGGATGMIGDPSFKANERVLQTKDQVEHNINKISAQLKQIIPNVNFVNNNTWLSNISLIDFLRDIGKHFNLSYLLAKESIATRIQTGLSVTEFCYTMLQAYDFYYLYKNNNCSIQIGGSDQWGNITSGIDFISDTINKNNKAAGLTINLLTKSDGQKFGKTESGTIWLDKTKTSEYEFYQFWFNQTDQDSINLLKCLTFLTKEQIDNLIKEHQNQSSKHLLQKALASEMTKFVHQQQGLDKALKLTEAFFSGDLFSLTNDLFKMALNSLPNTQINKDTKVIDALIEVKAASSKREAREFLTNKAIMINNQIIEDENTLISSFDLIQNKYLLVKKGKKKYFVILIK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_AKKM8
Sequence: MSSKKPVVLVIRDGWGRNPLGPDVAKEYGDATVLADTPFTDYLLANYPHSLLGASGEDVGLPDGQMGNSEVGHLNLGAGRVVFQDLCRVDNAIKDGSMGENAVLKTAFSQAASSRLHLLGLVSDGGVHSHINHLIGIVKYAYEAGVRDICIHAITDGRDCSPTSGVGFIRQLEEAVRPYGAKIATVVGRFYAMDRDKRWDRNKLAWDAIVLGRGEQCSCSPAEYVEQCYAKGETDEFLKPGIFAYGNEQRVRDNDVVFFFNFRADRARQMSDAFLYPEFDGFDREVTPKVHYVTLTEYDAKYPSPIVFEQEQLNNIFGQIVSEAGKTQLRIAETEKYAHVTFFFNGGVETQFPGEDRILVPSPREVATYDLKPQMSAAEVADKFVDAVNKYDVVIMNFANGDMVGHTGFVEAGIAACEAVDSALEKCVKKVLELGGKLLITADHGNAEHMRNEDGSPNTAHTTNLVDLIYVADDKDQVTLSDGILADVAPTLLSLMGLKQPAEMSGHSLVTPGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: KAXU1_HOTTA
Sequence: RCHFVVCTTDCRRNSPGTYGECVKKEKGKECVCKS
What is the function of this protein?
Blocks Kv1. 6/KCNA6 potassium channels.
What are the official names of this protein?
Tamulustoxin, TmTX, Potassium channel toxin alpha-KTx.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family.
Protein: KDSA_ACTP7
Sequence: MNNKIVKVGNIEVANDKPFTLFGGMNVLESRDMAMRVCEQYVEVTNKLGVPYVFKASFDKANRSSIHSYRGPGMEEGLKIFQELKDTFGVNIITDVHEIYQCKPVAEVVDIIQLPAFLARQTDLVEAMARTGAVINVKKPQFLSPGQMGNIVEKIAECGNENVILCDRGTNFGYDNLVVDMLGFNIMKKVSKGCPVIFDVTHSLQCRDPFGAASGGRRDQVTELARSGMAIGLAGLFLEAHPDPNNAKCDGPSALPLSKLEAFVSQMKAIDDLVKSFEEIDTSN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_HELAH
Sequence: MALLEIIHYPSKILRTISKEVVSFDAKFHQQLDDMHETMIASEGIGLAAIQVGLPLRMLLINLPREDGVQHKEDCLEIINPKFIETKGSIMFKEGCLSVPGFYEEVERFEKVKIEYQNRFAKVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKFEKELKELNKNPKNKS
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ACCD_SALNS
Sequence: MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFSASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQESEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXA_ACICJ
Sequence: MDQSPFPDIAHQTASFSDGLVLDCGTTLQRLEVAYRTYGSLNAEKSNAILICHALTGDQYVAEPHPLTGKPGWWNALVGAGKPVDTDRFFVICANVLGGCMGSTGPRSRRDHGADEPWSIDFPAITVQDMVRAQKKLVDWLGIERLFAVVGGSMGGMQVLAWASLFPDRVFAAVPIATAPYHSAQNIAFHEVGRQAIYTDPDFHGGHYRTHGVIPARGLAVARMTAHITYLSEAALTRKFGRRLQRQNALAAPVFGERFAVESYLEHQGSSFVRRFDANSYLVITRAMDYFDLAADHGGSLSAAFRGTKTRFLLVSFSSDWLFPTAESRAMARALNQVAANVSFVEIVSDKGHDAFLLDEPDFHRTVAGFISGAAEAAGLQ
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICAA_STAAC
Sequence: MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVDELEGITFLLACYNESETIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENNDFIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAVTGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGYWDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLLRDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFLLSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKALKRKKGGYATWSSPDRGNTQR
What is the function of this protein?
N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homomer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide.  Requires IcaD for full activity (By similarity).
What are the official names of this protein?
Poly-beta-1,6-N-acetyl-D-glucosamine synthase, PNAG synthase, Poly-beta-1,6-GlcNAc synthase, Biofilm polysaccharide intercellular adhesin synthesis protein IcaA, Biofilm PIA synthesis protein IcaA, Intercellular adhesion protein A, N-acetylglucosaminyltransferase IcaA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS2_METPP
Sequence: MSGDDTLARLAAVIESRRGGDPEASYVARLFHKGTDAILKKVGEEATEFVMAAKDGDRPKIVAEAADLWFHAMVALAHFGLTPAQVLAELERREGQSGLEEFALRKVRGREAESTKESGP
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLR15_PLAVT
Sequence: MRGHSALMMAVVTLAAVSSGAAEVANTAAVSSDYLIGTILTFAESDRLLRVNDVDDVPVYHYPPEKGKRTTFFEDRMKKKLANPEKIRRLYWKWYSMGYSAREVVQHLDQTDNRELKEIYHNLGVGYAEFVAKMNV
What is the function of this protein?
Effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 15.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm.
Protein: YPD1_CAEEL
Sequence: MSASKLWSCTETVLNGGIKLFLYSSKNTKLRVAIGEVPGPMVHGAVSFVTEADSDDGLPHTLEHLVFMGSKKYPFKGVLDVIANRCLADGTNAWTDTDHTAYTLSTVGSDGFLKVLPVYINHLLTPMLTASQFATEVHHITGEGNDAGVVYSEMQDHESEMESIMDRKTKEVIYPPFNPYAVDTGGRLKNLRESCTLEKVRDYHKKFYHLSNMVVTVCGMVDHDQVLEIMNNVENEHMSTVPDHFPKPFSFALSDIKESTVHRVECPTDDASRGAVEVAWFAHSPSDLETHSSLHVLFDYLSNTSVAPLQKDFILLEDPLASSVSFHIAEGVRCDLRLNFAGVPVEKLDECAPKFFDKTVREHLEEANFDMERMGYLIDQTILNELVKLETNAPKDIMSHIIGHQLFDNEDEELFKKRTNEIDFLKKLKSEPASYWVQLVNKYFTAPSATVIGVPNEELVDKIAEEEEKRIAAQCEKLGKKGLEEAGKSLEAAILENTANHPSAELLDQLIVKDLEAFDRFPVQSLTSNSPSLTPQQSTFLAQFPFHANLHNCPTKFVEIFFLLDSSNLSIEDRSYLFLYTDLLFESPAMIDGVLTSADDVAKHFTKDLIDHSIQVGVSGLYDRFVNLRIKVGADKYPLLAKWAQIFTQGVVFDPSRIHQCAQKLAGEARDRKRDGCTVASTAVASMVYGKNTNCILFDELVLEKLHEKISKDVMKNPEAVLEKLEQVRSALFSNGVNAHFVADVDSIDPKMLSSDLWTWVQADPRFGPGHQFSAEAGENVSLELGKELLIGVGGSESSFIYQTSFLDANWNSEELIPAMIFGQYLSQCEGPLWRAIRGDGLAYGANVFVKPDRKQITLSLYRCAQPAVAYERTRDIIRKIVESGEISKAEFEGAKRSTVFEMMKREGTVSGAAKISILNNFRQTPHPFNIDLCRRIWNLTSEEMVKIGGPPLARLFDEKCFVRSIAVHPSKLNEMKKAFPGSSKIKISDLQFAC
What are the official names of this protein?
Uncharacterized protein C05D11.1.
Protein: THAP4_RAT
Sequence: MVICCAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQRDNWTPTKYSFLCSEHFTKDSFSKRLEDQHRLLKPTAVPSIFHLSEKKRGAGGHGPARRKTTGAMRGHTSAATGKGTIGSSLSSSDNLMAKPESRKLKRASPQDDTAPKATPGAVSQEPGQSLERTPGDQAAPLARGQEEAQVSATEADHQKASSSAADAGGADKSGISMDDFTPPGSGACKFIGSLHSYSFSSKHTRERPSVPREPMDRKRLKRDIEPRCSGNSVAQSPPSSSLTATPQKASQSPSAPPTDVTPKPAAEAVQSEHSDANPMSINEVILSASGACKLIDSLHSYCFSARQNKSQVCCLREQVEKKNGELKSLRQRVSRSDSQVRKLREKLDELRRASLPYLPYLSGLLPPSHEPPKLNPVVEPLSWMLGTWLSEPPGVGTFPTLQPFQYLEEVHISHVGQPMLNFSFNSFHPETHKPMHRECGFIRLKPDTNKVAFVSAQNTGVVEVEEGEVNGQELCVSSHSISRISFAKEPHVQQITRKFRLNSEGKLEQTVSMATTTQPMTQHLHITYKKVTP
What is the function of this protein?
Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate.  Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively).  Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo, possibly modulating the transcriptional activity residing in the N-terminal region.
What are the official names of this protein?
Peroxynitrite isomerase THAP4, Ferric nitrobindin, Nb(III), THAP domain-containing protein 4.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the nitrobindin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes mainly in the cytoplasm and partially in the nucleus.
Protein: MFS2B_XENTR
Sequence: MAETSRELPLSTLTASTRRALRIRARQAREAKLSVLSKVCYAIGGAPNQVSGSASAFFLQIYLLDVALISPYQASLVLSLGKTWGGITDPIVGYCISKSKWTRIGRLMPWMLGCTPFLVVSYFLLWFVPTFETGRVLWYLAFFSCFQALSTAYHVPYTTLTMFLSTDQMERDSATAYRMTVEVLGTLIGAAVQGQIVASAHTGSHCNVTNMTGNLTADFLYEPTEYITSARQVYMIAAGIIGCLYLLCISVLFLGVKERDDPYALVAGKVIPFFKGFRETMQFGPYLNLISSFLLISAAVQIQQSNFVLFCTHAADLQDHFQNLVLTILIAAVLSIPFWQWFLQKFGKKMAAFGISLMIPFSIMLVTISSLVVAYVVAVASGLSIAASLLLPWSMLPDVVDNFRLTNPQGKGLEAIFYSSFVFFTKLSAGIALGISTLSLQFADYNTSLCKQSYSVVLTLKLLIGAAPALMIIIGLTILAFYPITEDTRKETELALDVIRMRTRRSTLIVI
What is the function of this protein?
Lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets.  Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology.  Sphingosine-1-phosphate export from platelets is required for platelet aggregation and thrombus formation.  In addition to export, also able to mediate S1P import.
What are the official names of this protein?
Sphingosine-1-phosphate transporter MFSD2B, Major facilitator superfamily domain-containing protein 2B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the cell membrane and intracellular membranes.
Protein: RL33_NEIMF
Sequence: MRDKIKLESSAGTGHFYTTTKNKRTMPGKLEIKKFDPVARKHVVYKETKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MLCD_DICDI
Sequence: MASKLNEEAQSEFKEGFALYDGNKDGKLEAAELANTLRWLGQNPSQSEINEILREFGSNNQMGVDGLFNYLGRKVVDDFDEKEIIEAFQVFDKDGKGMIGASDLRHILTNLGERLPEEQVEEMLRQAVGSGDGAINYEPFVRNMLKK
What is the function of this protein?
Functions as the light chain for myosin-D.  Has low affinity for calcium.
What are the official names of this protein?
Myosin-ID light chain, Calmodulin-like protein mlcD, Myosin light chain mlcD, MlcD.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALYT_ALYOB
Sequence: QGRLGTQWAVGHLM
What are the official names of this protein?
Alytesin.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1378_NEIMB
Sequence: MRLTTKGRFAVTAMLDLAMNAQTGAVKLSAISERQNISLSYLEQLFGKLRRAGLVESLRGPGGGYILAAPAARINIAQIIAAAEDRLDATQCGSKANCHHGAPCLTHDLWENLNKTINDYLGSVTLQSIIEQKNNGDGSRVVQFTHIH
What are the official names of this protein?
Putative HTH-type transcriptional regulator NMB1378.