PharMolix/UniProtQA huggingface dataset:
Protein: ARHG5_HUMAN
Sequence: MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQQSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGSESGTIRQGEELPPEELQESQGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQDVMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCDLFPGASYLMTQIPGTQTESRAEELSPAALSPSLEPIRCSHQPISLLGSFLTEESPDKEIDQNSQQEESRLRKGTVSSQGTEVVFASASVTPPRTPDSAPPSPAEAYPITPASVSARPPVAFPRRETSCAARAPETASAPLSMDDPSPCGTSEMCPAALYGFPSTGTSPPRPPANSTGTVQHLRSDSFPGSHRTEQTPDLVGMLLSYSHSELPQRPPKPAIYSSVTPRRDRRSGRDYSTVSASPTALSTLKQDSQESISNLERPSSPPSIQPWVSPHNPAFATESPAYGSSPSFVSMEDVRIHEPLPPPPPQRRDTHPSVVETDGHARVVVPTLKQHSHPPPLALGSGLHAPHKGPLPQASDPAVARQHRPLPSTPDSSHHAQATPRWRYNKPLPPTPDLPQPHLPPISAPGSSRIYRPLPPLPIIDPPTEPPPLPPKSRGRSRSTRGGHMNSGGHAKTRPACQDWTVPLPASAGRTSWPPATARSTESFTSTSRSKSEVSPGMAFSNMTNFLCPSSPTTPWTPELQGPTSKDEAGVSEHPEAPAREPLRRTTPQQGASGPGRSPVGQARQPEKPSHLHLEKASSWPHRRDSGRPPGDSSGQAVAPSEGANKHKGWSRQGLRRPSILPEGSSDSRGPAVEKHPGPSDTVVFREKKPKEVMGGFSRRCSKLINSSQLLYQEYSDVVLNKEIQSQQRLESLSETPGPSSPRQPRKALVSSESYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEVKFELIVSEASYLRSLNIAVDHFQLSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEENFENNIFSFQVCDVVLNHAPDFRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLESDPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEQLIRDCNNNVQSMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSASPGLRRKLNTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGPHKNLFRLFLRQNTQGAQAEFLFRTETQSEKLRWISALAMPREELDLLECYNSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGERGWFPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQA
What is the function of this protein?
Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624).  Strongly activates RHOA (PubMed:15601624).  Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity).  Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624).  Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653).  Required for SRC-induced podosome formation (By similarity).  Involved in positive regulation of immature dendritic cell migration (By similarity).
What are the official names of this protein?
Rho guanine nucleotide exchange factor 5, Ephexin-3, Guanine nucleotide regulatory protein TIM, Oncogene TIM, Transforming immortalized mammary oncogene, p60 TIM.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, podosome.
Protein: RH14_ORYSJ
Sequence: MASAAAAAATARGPRYAPPDPTLPKPWRGLIDGNTGYLYFWNPETKAVQYDRPTAPPPSSPPAQQPPERPRNSDPAESQAQAGASRTQNAAPADDRARNDHLNDHFERRTEAAGSHAQNVPFTEQNTRSNPSSQPCSAAGVYPAQNVFSEAASGDRTSPEAYRAKHEITIVGNEAPAPFMTFQSTGFPPEILREVQQAGFSAPTPIQAQSWPIALRNRDIVAVAKTGSGKTLGYLIPGFILLKRLQHNSRDGPTVLVLSPTRELATQIQDEAKKFGRSSRISSVCLYGGAPKGPQLRDLERGADIVVATPGRLNDILEMRRVSLHQVSYLVLDEADRMLDMGFEPQIRKIVKQVQPKRQTLMFTATWPKEVRKIASDLLSNPVQVNIGNTDQLVANKSITQYVDVITPPEKSRRLDQILRSQEPGSKIIIFCSTKRMCDQLARNLARQYGASAIHGDKSQAERDSVLSEFRSGRCPILVATDVAARGLDIKDIRVVVNYDFPTGVEDYVHRIGRTGRAGATGVAYTFFCDQDSKYASDLVKILEGANQSVSQQLRDMVSRGGYGGRSRRWASSDDSYGGRGYDSGYTSRSTDNYNSGYGSQSGNGSSFHSSFHNSNSGNQFGDTSGFQTSFHNSSSNNQTSDNPSFHASSNNDQPGDGLSFHARFYSSSRGSDQSRTNNAGFRDRSRSPPSNRNHEDPGSKAVGVSNW
What is the function of this protein?
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 14.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FB321_ARATH
Sequence: MVELSEIPGDPNGADPNNNPQEEDEENLPILLQLPEELIERIIAHFPQCYSPSPILVCETFRQVINSDHFYYVTRSLLSFTKPVLYALIAFQAYTRPSWFFLRQSNIALQLHRIRSYEPVQGLWESWGEESELMRFWHSVSSCVVGDLLYALDLTCALEHPIVVYYPNEFVWRPVMGVDTAHLPILCEYRSTLANFDGKLVILGGGDCSESSSEIWCVEIALETRQGDQIWGVVKSVSIVSRDLPMRHVIELCRTVMV
What are the official names of this protein?
Probable F-box protein At2g29610.
Protein: RL27_COXB1
Sequence: MAHKKAGGSTRNGRDSNPKMLGVKRFGGERVLAGNIIVRQRGTHYRPGENMGMGRDHTLYALIEGKVKFTRKGPKKRNFVSIEPLEESQP
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: LONM_ASPNC
Sequence: MLRGQTLPWRAALQQVSRPFIPRPLLAPSRYNVTARSILNASRLHRSLPTSRAFSSSSIRRREKPPPGDEKDDPAQKEQKDANEEKDVERAPDARRKAADPSGKQGSSHEPGAPTSGFARRKEKAGADKEQRGLEEDSKKDGNAVEGKGNSSDTPSPIPVNGGSDSRPSGANNGGNEDGGKKGKKGSGEKALQKPSVPEVYPQVMAIPIAKRPLFPGFYKAITIRDPNVAAAIQDMMKRGQPYVGAFLFKDENADGDVIENLDDVYDVGVFAQITAAYPLRGEASGVTAVLYPHRRIKVSSLLPPSDAAKAGTTDEKTSERRGDVVASFEEGTAELAPKDHYEPTSFLRKYPVSLVNVENLAEEPYDKKSAIIRAVTSEIVNVCKEIASLNPLFRDQISAFYTDQFPGNLSDEPAKLADFAAAVSAGELNEMQEVLELMNIEERLPKALVVLKKELMNAQLQSKISKDVEAKIQKRQREYWLMEQMKGIKRELGIESDGKDKLVEKFKEKAEKLAMPDAVKKVFDEELNKLAHLEPAASEFNVTRNYLDWLTQIPWGQKSVENFGIQHAVKVLDEDHYGLKDVKDRILEFIAVGKLRGTVEGKILCLVGPPGVGKTSIGKSIARALNRQYYRFSVGGLTDVAEIKGHRRTYVGALPGRIIQALKKCQTENPLILIDEIDKIGRGHQGDPSSALLELLDPEQNSSFLDHYMDVPVDLSKVLFVCTANVTDTIPRPLLDRMELIELSGYVADEKMAIAQRYLAPAARELTGLKEVDVNLTEEAVEELIKSYCRESGVRNLKKQIEKVYRKAAYKIVRDLGEDVLAEEKALTDEGKAVQEESQKETESPDSKSPVDPEKSTTETPRVALKVPESVQLSIGKDSLTDYVGPPIFTADRLYDTFPPGVTMGLAWTSMGGAALYVESILENALTPQSRPGIDITGNLQNVMKESSQIAYSFAKSVMAKQFPENRFFEKAKLHMHCPEGAVPKDGPSAGITMATSLLSLALNHPLDPTIAMTGELTVTGKVLRIGGLREKTVAARRAGAKKIVFPADNMSDWLELPENIKEGIEGHAVGWYSEVFDLLFTDLDKGAANHVWQKQLAEKPEKKSNEVEEDE
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner.
What are the official names of this protein?
Lon protease homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MIAB_FRAAA
Sequence: MTGRSYEVRTFGCQMNVHDSERLSGLLESAGYVPAPPGSEADVVVFNTCAVRENADNRLYGNLGQLVPVKKGHPGMQIAVGGCLAQKDRSTILDRAPWVDVVFGTHNLHRLPVLLERARHNAAAELEIAEALEVFPSSLPTRRASHHSAWVSISVGCDNTCTFCIVPSLRGRERDRRPGDVLAEVEALVGEGALEITLLGQNVNSYGRSLGDPGAFAKLLLACGRVDGLERVRFTSPHPRDFTDDVIEAMAATPNVCHQLHMPLQSGSDDVLRRMRRSYRRDRFLGIVERVRAAMPDAAITTDIIVGFPGETEADFADTLDVVRQARFAGAFTFQYSPRPGTPAATMDGQIDRTTVAERYARLVALQDEVSWAQNRELVGRRVELLVAEGEGRKDDATGRLSGRARDGRLVHFRAGAGLAARPGDVVETVVTRAAPHHLTADGPLLSHRRTRAGDAWELARTAPVPAAGDGAGTTAARQTVALGMPSVGPAPSPGRR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_XYLF2
Sequence: MGLIDFLRNKTKTAETAKNRLQIIIAQERTQRGGPDYLPLLQRELLEVIKKYVKIDADAVKVDLIKDGANDVLDISVALPDDSER
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SYM_THEKO
Sequence: MVRYMVTSALPYANGPIHAGHLAGAYLPADIFVRYLRLKGEEVLFICGTDEHGTPITFRALKEGRSPREIVDEFHEHIKTTFERAKISFDFFGRTELPVHYRLSQEFFLKALENGHLVKKVTKQAYCEHDKMFLPDRYVIGTCPYCGAENQRGDQCEVCGHPLTPEILINPRCNICGNPITFKDSAHYYIRMQDFEERLKKWVESQEHWKPNVRNTVLGWINEGLEERAITRDLDWGIPVPLDDEDVKGKVLYVWFEAPIGYISITIEHLKREGKENEWKKFWLNLDGETKVIHFIGKDNIPFHAIFWPAFLMAYGKYRDEEVEAEWNLPYDIPANEYLNLEGKKFSTSRNWAIWVHEFLDVWPADYLRYYLTAIMPETRDSDFSFEDFKKKINEELVNNLGNFVHRAMTFVNRYFDGVVPERGELNDLDRQALEEIEKAFKETGELISNYRFKDALKRVMELAIFGNRYFDYQKPWKTAKENRERTATTVNVSLQIVKALGILLEPFLPDASEKIWHLLNLEEVKKWSFEELPAGHRVRKAFPMFRKVTDGEIIYFIVNYIGRGNPDSAKILLNKYYKQEDVVKVTLERFGEKRKDEALALLKSIYGDEFKGEKPEKAGKAEKKEKVKEGKKMEYVSFDEFAKLDLRVGKIIEVNDHPNADRLYVVKVDLGDEVRQLVAGLKKYYKPEELLGHYVVIIANLEPKKLRGVESQGMLLAADDGERVALLMPDKEVKLGARIR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUSR_ECOLI
Sequence: MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLEFFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVGYMLEVPDGQ
What is the function of this protein?
Member of the two-component regulatory system CusS/CusR involved in response to copper and silver.  Activates the expression of cusCFBA, hiuH and plasmid pRJ1004 gene pcoE in response to increasing levels of copper or silver ions.  Can also increase the basal-level expression of copper resistance gene operon pcoABCD.
What are the official names of this protein?
Transcriptional regulatory protein CusR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_ACIBS
Sequence: MLIIPAIDLKDGKCVRLKQGRMEDDTVFSDDLVATAQHWVNEGARRLHLVDLNGAFAGTPIHKPVVEAIAKAQPELPIQIGGGIRSLETIEHYLEAGVTFVIIGTKAVQEPEFVEEACKSFAGHIIVGIDAMNGMVATDGWANVTDVKATDLAKRFADAGVSSIVYTDIARDGMMQGVNVEQTVNLAQYSGLPVIASGGVTNLDDVRNLKGQLGILGAITGRAIYEGTLNLREAQLLLDENRL
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_SHIB3
Sequence: MTLSFVTRWRDELPETYTALSPTPLNNARLVWHNTELANTLSIPSSLFKNGAGVWGGEALLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETAEPGAMLMRVAPSHLRFGHFEHFYYRRESEKVRQLADFAIRHYWSHLEDDEDKYRLWFSDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGQRMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMMELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: DAPD_ACIB5
Sequence: MSQLSTIIEQAFEDRANFTAADCPSEIRQAVEEAIAGLDNGTLRVAEKINGEWVVHQWLKKAVLLSFKLNDNKPIESCDLRFYDKVETKFSGWTEEQFKAAGVRVVPPAVARRGSFQAKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVPGNLPSADGKYSLYAAIIVKKVDAQTRAKTSLNDLLRAD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_MAGMM
Sequence: MISAAYAATHAAAEHAQSGMPQFDSSTFSSQMFWTVISFVALLLLLKKFVVPAISDVLEARASRIEEELKAAENERKEAAALLVDQRAEVKAEREKIAQLLESARKEADALREQEKAELEAELAKLKSQATQDIEQARRQAMSEVRGVVVEVALAVTEKLITKSIDKAEANKLADEAIRHLEANKDQLH
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TAL_DESPS
Sequence: MKFFIDTANLDEIREGVELGLVDGVTTNPSLIARENLPFEELIAEICKIVDGPVSAEVISLDAPGMVAEAKKLASIDEKVVIKVPMTAEGLKAVRQLSAAGIKTNVTLIFSANQALLAAKAGASYVSPFVGRLDDIGVNSADLISDILTIFDNYGYASEVIVASVRGPQHVLDSALLGADIATIPLKTIKQLTKHPLTDKGMEQFLADWEKRTQ
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLAB1_TRIST
Sequence: MGRFIFMSFGFLVVAVSLSGTGAGFCCPLGWSSYDEHCYKVFNQRKTWDDAEKFCTQQHKGSHLLSFHSSEEVDFVVSKTYPILKEDFVWIGLSDVWSECTKEWSDGTKLDYKAWSGESECIASKTTDNQWWSRSCNTTYYVVCKFQA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec stejaggregin-A subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: IOLG_HALH5
Sequence: MTLRFGVIGTGAIGREHMKRIENKLSGGKIVAVTDMNQEAAKQVVTQMKLEADVYPDDRSLVAADNVDAVLVTSWGPAHEANVLAAIEAGKYVFVEKPLATTAEGCMKIIKAEMNHGKRLVQVGFMRRYDKGYVQLKKAIDDHFIGEPLMVRCAHRNPEVGESYIDDMAIHDTLIHEIDVLHWLIDDEYESVSVSFPKKTKHALPHLRDPRVVTLETKGGVLITAEVFVNCKYGYDIQCEVIREEGIASLPEVDSISFRKRATLGTNILMDWKQRFIEAYDVELQHFIDSIKQSGEPSGPNAWDGYVAAITADAALKASNSGQKQFISLKEKPAFYSVKKENAHEAML
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively.
What are the official names of this protein?
Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, MI 2-dehydrogenase/DCI 3-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: TSAC_VIBCH
Sequence: MALVENLQQAVDALRKGCVIAYPTEGVFGLGCDPDNQTAMLRLLAIKQRPVEKGVILIAASYAQLRPYVDETQLTAEQLTQVLASWPAPLTWVMPASGDTPSWVRGQFDTVAVRVSDHPVVQKLCLAFGKPLTSTSANLSGQPACVTQQEVMVQLGNQIAVVVEGKTSGRHGPSEIRDARSLQVLRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLB_STAHA
Sequence: MSDIIFLNGMRFYGYHGALHAENELGQIFIVDVTLKVDLTEAGKTDNVKDTVHYGEVFEDVKNIVEGPSCQLIEHLAERIAKRI
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.  Can also catalyze the epimerization of carbon 2' of dihydroneopterin to dihydromonapterin.
What are the official names of this protein?
Dihydroneopterin aldolase, DHNA, 7,8-dihydroneopterin 2'-epimerase, 7,8-dihydroneopterin aldolase, 7,8-dihydroneopterin epimerase, Dihydroneopterin epimerase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: CWC25_GIBZE
Sequence: MGGGDLNLKKSFHPALRRNQQAVWDEEQKALAERKRTQQRLDEIKEERAKEEVQRQLEAAGGKKKVDRVEWMYQGPNDGQTGTTEETEAYLLGKRRIDNLIKGTEHKKLEKDAGTESFMALQNANTARDTAAKIREDPLLAIKRQEQAAYEAMMNDPARRRQLLASRGIDEDKKDKSRRKEDRHRRRHRHRSADGEDRHHRRRRSYSRSQSPRRRDGSREDRHRRRRDDSRDRHSRRRRDGSDEEGRRDRDNRSGGDRHRHDGDRRHSDEPRDERRDNRRDERPRDNNRQYSRRSYPSDRRPRHNEEDDKAKEEERQRKLAAMQSAATELDVDRQERLADLEKREQAAREADNKARERGGDRGFVNKLHQQAEHKGLAERMGGARRGYQKDDD
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC25.
What is the protein family that this protein belongs to?
Belongs to the CWC25 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS12_TROWT
Sequence: MPTIQQLVRKGRRPKVNKTKSPALRGNPQQRGVCSRVYTTTPKKPNSALRKVARVKLSNGTEVTVYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYKVVRGALDAQAVKDRKQARSRYGAKMEKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: Y844_AZOVD
Sequence: MTDTDVQAPKIEFPCERYPIKVIGDAGEGFADLVVEVIQRHAPDLDSSTLRLRDSRNGRFLSVQVLITATGVEQLQAIHLDLRATGRVHMVL
What are the official names of this protein?
UPF0250 protein Avin_08440.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: OTC_ECO57
Sequence: MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKPFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAT2_COCSA
Sequence: MDSTNSISLAEAVKIAEARFKAAVQGCKDDWHNGNDLVILQDNIPQLFGGILIEHFKHCVGEVSGFPVELTVMDSGNSNYHTLVQMPKNNMRLSQVASSPKSAKTSPSEQASINLRAVAAGLKKAPRPMNCWIIFRDAMHKHLRAEFPHLTIQEISTQCSQIWHNLSPEAKRPWQDAAQSAKEEHLRQHPNYKYTPRKPGEKKKRQSRKSKRAAATTTAPEVLQFQLSPNLIPTVPEVTDQPPLTANPVAATGDSPCPEDVLNYFDPNIFPEIYPQAPMAADFFYNAESIRHGLLDAEFDIDFNMDTTFALFDDEMLAFRDGADGDATLPSSFQDTY
What are the official names of this protein?
Mating-type protein MAT-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MYG_SARCH
Sequence: MADFDAVLKFWGPVEADYTSHGGLVLTRLFKEHPETQKLFPKFTGIAQADMAGNAAISAHGATVLKKLGELLKAKGNHAAILKPMANSHATKHKIPINNFKLISEIIVKVMQEKAGMDAGGQQALRNVMAAVIADLEANYKELGFSG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MYLK2_RAT
Sequence: MATENGAVELGTQSLSTDHPPTDAAGDGSPASEKEPSLPDTEKDLGPTNTKKDPGAPDPKKNPDPPSLKKTPEAPGPEKKGDSAPASASNQGPSGEGDGGGGPAEGGTGPPAVLPQPTATADASIQKLDATQAPSGNQESGEAKAGKKAAECREAGRRGSPAFLHSPSCPAIISCSEKTLAMKPLSETTELIFAGVSETPDPQDPGPAKDEGGTNTLADGKEEAEAGQAEQAKVQGDTSQRIGFQAVPSERAEVGQALCLTAKEEDCFQILDDCPPPPAPFPHRIVELRTGNVSSEFSMNSKEALGGGKFGAVCTCTERSTGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYSAIETSHEIILFMEYIEGGELFERIVDEDYQLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLITKDQSARMSAEQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV
What is the function of this protein?
Implicated in the level of global muscle contraction and cardiac function (By similarity).  Phosphorylates a specific serine in the N-terminus of a myosin light chain.
What are the official names of this protein?
Myosin light chain kinase 2, skeletal/cardiac muscle, MLCK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
Protein: RL9_PSEF5
Sequence: MELILLEKIANLGNLGDKVNVKAGYGRNYLLPFGKATAATAANLAAFEARRAELEKLAAEKKASAETRAAQLAELEVTITATAGDEGKLFGSIGTHDIADALTASGVEVAKSEVRLPNGTIRNVGEFDVAVHLHAEVEATVRVVVVAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NADD_PSEPK
Sequence: MASCAARGPAELSKAQAVRRIGILGGTFDPVHIGHLRSALEVAEFMGLDELRLLPNARPPHRDTPQVAAQDRLAMVREAVQGVACLSVDARELERDKPSYTIDTLESIRAELSGHDQLFLVLGWDAFCGLPAWHRWEELLQHCHILVLQRPDADVEPPDELRNLLAARSESDPTAMSGPAGNISFVWQTPLAVSATQIRQLLASGKSVRFLVPDAVLAYIEAHELYRAPN
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: T23O_BURCH
Sequence: MQPPGGDAPAGCPFSGARAAQPAQAPHEAPHVPGEADAQAGWHNAQLDFSKSMSYGDYLSLNSILDAQHPLSPDHNEMLFIIQHQTSELWMKLALFELRGALDAVRTDALPPAFKMLARVSRILEQLVQAWNVLSTMTPSEYSAMRPYLGQSSGFQSYQYRQLEFLLGNKNAQMLQPHAHRPDILEQVRATLEAPSFYDEVVRLLARRGFPIAAERLERDWTQPTRHDETVEAAWLEVYRHPQQHWELYEMAEELVDLEDAFRQWRFRHVTTVERIIGFKQGTGGTSGAPYLRKMLDVVLFPELWHVRTTL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.