PharMolix/UniProtQA huggingface dataset:
Protein: DPOE1_MOUSE
Sequence: MVLRNSGRRHPEPGADGEGSRDDGPSSSVSALKRLERSQWTDKMDLRFGFERLKEPGERTGWLINMHPTEILDEDKRLVSAVDYYFIQDDGSRFKVALPYMPYFYIAARKGCDREVSSFLSKKFQGKIAKLENVPKEDLDLPNHLVGLKRSYIKLSFHTVEDLVKVRKEISPAVKKNREQDHASDEYTTMLSSILQGGSVITDEDETSKKIADQLDNIVDMREYDVPYHIRLSIDLRIHVAHWYNVRFRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHIQETKPTIMVTYNGDFFDWPFVEARAAIHGLSMYQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHMLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPVEQATNFQEVCEQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAIVDEATCAACDFNKPGASCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHVTKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDASEVKRCKNMEILYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTNAKKPKLTISYPGAMLNIMVKEGFTNHQYQELTEPSSLTYVTHSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDIYKQKKISELFVLEGKRQIVMAQASENSLSLCTPDMEDIGLTKPHHSTVPVATKRKRVWETQKESQDIALTVPWQEVLGQPPSLGTTQEEWLVWLQFHKKKWQLQAQQRLALRKKQRLESAEDMPRLGPIREGPSTGLGSFLRRTARSIMDLPWQIIQISETRQAGLFRLWAIIGNDLHCIKLSIPRVFYVNQRVAKAEDGPAYRKVNRALPRSNIVYNLYEYSVPEDMYQEHINEINTELSVPDIEGVYETQVPLLFRALVQLGCVCVVNKQLTRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHTQGHKALFGVFIPSQRRASVFVLDTVRSNQMPGLSALYSSEHSLLLDKVDPKLLPPPKHTFEVRAETNLKTICRAIQRFLLAYKEERRGPTLIAVQSSWELCRLTSEIPVLEEFPLVPIRVADKISYAVLDWQRHGARRMIRHYLNLDLCLSQAFEMSRYFHIPVGNLPEDISTFGSDLFFARHLQHHNHLLWLSPTSRPDLGGKEADDNRLVMEFDDRATVEINSSGCYSTVCVELDIQNLAVNTILQSHHVNDMEGAGSMGISFDVIQQASLEDMVTGNQAASALANYDETALCSSTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLQSPCSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSVVYANFNRIILCTKKRRIEDALAYVEYITNSIHSKEIFHSLTISFSRCWEFLLWMDPSNYGGIKGKVPSSIHCGQVKEQDSQAREETDEEEEDKEKDEEEEGMGESEVEDLLENNWNILQFLPQAASCQSYFLMIVSAYIVAVYQSMKEELRHSAPGSTPVKRKGASQFSQESEGATGSLPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNTTEPSEMFPVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCHSYVLPEVICHSCNFCRDLDLCKDSSFSQDGAILPQWLCSNCQAPYDSSAIESALVEALQRKLMAFTLQDLVCLKCRGMKETHMPVYCSCAGDFTLTIRTEVFMEQIRIFQNIAKYYSMSYLQETIEWLLQTSPVSNC
What is the function of this protein?
Catalytic component of the DNA polymerase epsilon complex (By similarity).  Participates in chromosomal DNA replication.  Required during synthesis of the leading DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork.  Has 3'-5' proofreading exonuclease activity that corrects errors arising during DNA replication (By similarity).  It is also involved in DNA synthesis during DNA repair (By similarity).
What are the official names of this protein?
DNA polymerase epsilon catalytic subunit A, 3'-5' exodeoxyribonuclease, DNA polymerase II subunit A.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOE_MYCBO
Sequence: MTQPPGQPVFIRLGPPPDEPNQFVVEGAPRSYPPDVLARLEVDAKEIIGRYPDRRSALLPLLHLVQGEDSYLTPAGLRFCADQLGLTGAEVSAVASFYTMYRRRPTGEYLVGVCTNTLCAVMGGDAIFDRLKEHLGVGHDETTSDGVVTLQHIECNAACDYAPVVMVNWEFFDNQTPESARELVDSLRSDTPKAPTRGAPLCGFRQTSRILAGLPDQRPDEGQGGPGAPTLAGLQVARKNDMQAPPTPGADE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit E, NADH dehydrogenase I subunit E, NDH-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the complex I 24 kDa subunit family.
Protein: YJHX_SALPB
Sequence: MNLSRQEQRTLHVLAKGGRITHIRDASGRVTAVECYSREGLLLADCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRAQPDNR
What are the official names of this protein?
UPF0386 protein YjhX.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: ECM38_YEAST
Sequence: MLLCNRKVPKTLNTCFILHIFTLLTLGVLVSGMPSKMVSFASQETLQRINNLLRGSANRDVDIIAEYLKKDDDDDGGDKDHHNIDIDPLPRRPSLTPDRQLLKVGLHGAISSDLEVCSNLTINEVLLKFPGSNAADAAVTQALCKGMVNFFNSGIGGGGYVVFSGKDDEDHLSIDFREKAPMDSHKFMFENCSLCSKIGGLAVGVPGELMGLYRLFKERGSGQVDWRDLIEPVAKLGSVGWQIGEALGATLELYEDVFLTLKEDWSFVLNSTHDGVLKEGDWIKRPALSNMLMELAKNGSVAPFYDPDHWIAKSMIDTVAKYNGIMNLQDVSSYDVHVTKPLSMKIRKGANFIPDNDMTVLTSSGSSSGAALLAALRIMDNFQNQEGGDYEKETTYHLLESMKWMASARSRLGDFEGEALPKHIEEVLDPEWALKAVKSIKRNSQDGNFKTLENWTLYDPAYDINNPHGTAHFSIVDSHGNAVSLTTTINLLFGSLVHDPKTGVIFNNEMDDFAQFNKSNSFELAPSIYNFPEPGKRPLSSTAPTIVLSELGIPDLVVGASGGSRITTSVLQTIVRTYWYNMPILETIAYPRIHHQLLPDRIELESFPMIGKAVLSTLKEMGYTMKEVFPKSVVNAIRNVRGEWHAVSDYWRKRGISSVY
What is the function of this protein?
Catalyzes the transfer of the gamma-glutamyl moiety of glutathione (GSH) and other gamma-glutamyl compounds to amino acids and peptides.  Major GSH-degrading enzyme, catalyzing the hydrolytic release of L-glutamate from GSH.  Plays a role in the turnover of the vacuolar GSH, serving as an alternative nitrogen source during nitrogen starvation.
What are the official names of this protein?
Glutathione hydrolase proenzyme, CIK1 suppressor protein 2, Extracellular mutant protein 38, Gamma-glutamyltransferase, Gamma-glutamyltranspeptidase, Gamma-GT.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein.
Protein: LEUD_BRASB
Sequence: MDKFTTLEGVAAPLKIINVDTDMIIPKQYLKTIKRTGLGKGLFSEQRYKDDGSENPDFVLNQPAYRNAKILVAGDNFGCGSSREHAPWALLDFGIRCVISTSFGDIFYNNCFKNGILPIRVSQADLDKLFDDAERGANATLTVDLASQEIRGPDGGTVKFDIDPFRKHCLLNGLDDIGLTLEKKASIDSYEAKLAERAWA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: MCPH_PSEPK
Sequence: MRIWRKSIQLQLITSMGAALLASILVVVIIFTVALNRLTDRYLVDTALPASIEAIRNDIERMLGQPLVAAADIAGNTLLRDWLAAGEDPAQAPQFIEYLTAAKQRNHAFTTLFASTETGHYYNENGLDRTLSRSNPKDKWFYGYIDSGAERFINIDIDGATGELALFIDYRVEKEGKLVGVAGMGLRMTELSKLIHDFSFGEHGKVFLVRNDGLIQVHPDAAFSGKRQLAEQLGADAAKGVMTGGESLRSSRFSRDGERYLALGLPLRDLNWTLVAEVPESEIYAQMHQAVWLTSLIGGAVALVSLLLVVLLARGLVRPIRRVTAALVQIGSGAGDLSHRLDDSRQDELGDLARGFNRFLDSQRSLIGEVLSTSERLRRAVEQVTQVVDNTAERSGRQQEMTEMVATAVHEMGLTVQDIARNAGDAAQASQSARDEALQAREVVQRSIRGIEGMSGDIGKAADAVSQLADEVASVDEVLAVIRSISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRTLARRTQLSTDEVQQMIQRLKLGAGSAVSSMQAGQQATGSGVESSQRTGASLSAITDQVEHISDMNHQVATATEEQSAVTEEINRTVQGISDLARETAAEVQGCREECQALRGLADDLARQMGGFRL
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.  McpH is a chemoreceptor that binds and responds exclusively to intermediates of the purine degradation pathway.
What are the official names of this protein?
Methyl-accepting chemotaxis protein McpH.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRP1_ARATH
Sequence: MVADKSKKSKIEEKGEEENLEQIDAELVLSIEKLQEIQDDLEKINEKASDEVLEVEQKYNVIRKPVYDKRNEVIQSIPGFWMTAFLSHPALGDLLTEEDQKIFKYLNSLEVEDAKDVKSGYSITFHFTSNPFFEDAKLTKTFTFLEEGTTKITATPIKWKEGKGLPNGVNHDDKKGNKRALPEESFFTWFTDAQHKEDAGDEIHDEVADIIKEDLWSNPLTYFNNDADEEDFDGDDDGDEEGEEDDDDEEEEDGEE
What is the function of this protein?
Acts as histone H2A/H2B chaperone in nucleosome assembly, playing a critical role for the correct expression of genes involved in root proliferation and patterning.  Required with NRP2 for the maintenance of cell proliferation and differentiation in postembryonic root growth.  Involved in both intramolecular and intermolecular somatic homologous recombination.
What are the official names of this protein?
NAP1-related protein 1, Nucleosome/chromatin assembly factor group A6, Protein SET homolog 1.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EM55_HUMAN
Sequence: MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQMFMRAQFDYDPKKDNLIPCKEAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVASMAQSAPSEAPSCSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVVRLPAFKRKTLVLIGASGVGRSHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWVY
What is the function of this protein?
Essential regulator of neutrophil polarity.  Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
What are the official names of this protein?
55 kDa erythrocyte membrane protein, p55, Membrane protein, palmitoylated 1.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cell projection, stereocilium. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with PALS1 in the retina, at the outer limiting membrane (OLM) (By similarity). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC) (By similarity). Colocalizes with NF2 in non-myelin-forming Schwann cells (PubMed:19144871).
Protein: VF203_IIV6
Sequence: MSIQTLIIISIVIFILWLTFTSGSSYDPYHNFMKQKNHIFHNINKWVKKDVSKFLETLLKPFDKQCVGKTRTIESLEKLRTENNVEFKKLLNCGYIHNLFILIGLSVWEDFSKLHTETSLNTFINECLIPISTSPNFVAGNMLYTQTKPGVLKCLNDKNL
What are the official names of this protein?
Uncharacterized protein 203L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 203L/325L family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PMGT2_TAKRU
Sequence: MSVGTLLNGLLVSIVAALLWKYSKLSEHAALLEEELHMTRQSQELSQAHIDYHVALQALQEHGTRMVCTGKMHTDRICRFDYLCYCSEAEEFVFFHSNSSVMLPNLGSRRFQPALLDLSSVEDHNTQYFNFLELPAATLRFMPKPVFVPDVTLILNRFNPDNLMHVFHDDLLPAFYTMKQFLDSDEDARLVFMEGWEEGPHFELYRLLSNKQPLLKEQLRNFGKLMCFTKSYIGLSKMTTWYQYGFVQPQGPKANILVSGNEIRHFAKVLMEKMNITRAAGGEKDQGNAEDEKPKDEYIVVFSRSTTRLILNEAELIMALAQEFQMRVVTVSLEEQSFPSIVQVISGASMLVSMHGAQLITSLFLPPGAVVVELYPFAVNPDQYTPYRTLASLPGMDLHYIPWRNTEEENTVTHPDRPWEQGGIAHLEKEEQEQIMASKDVPRHLCCRNPEWLFRIYQDTLVDIPSFLEVLQEGVKAKPLLKKSKLSSTLHPGRVRDPQCQTSVQTSNEAKLTVSWQIPWNLKYLKVREVKYEVWIQEQGENTYMPYILPQQNYTFSDNIKPFTTYLVWVRCIFNKNLLGPFADVLMCRT
What is the function of this protein?
O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein.  Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity).
What are the official names of this protein?
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, POMGnT2, Extracellular O-linked N-acetylglucosamine transferase-like, Glycosyltransferase-like domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 61 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: YRBG_BACSU
Sequence: MEELLTIAFRTVVLYFVILVIFRFMGKREIGELSILDLVVFIMMAEIAVLAIENVDDHLFHTILPMLVLMIIQVTLAYFSLKNRKVRQLLDGKPTIIIKYGKIDEEAMKSQRYNFDDLMVQLRENSIDRVADVSFAILEPSGKLTIVKKENSGEHRQLEMPLIIDGFIQTENLSRISKDRKWLLESLQKHGYTNPSDISFCSFTDGEIYIDEKDGHRT
What are the official names of this protein?
UPF0702 transmembrane protein YrbG.
What is the protein family that this protein belongs to?
Belongs to the UPF0702 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIPA_LEIXX
Sequence: MSAEPEGRRMLRLEVRNAQTPIERKPEWIKTRATMGPEYRQLHSLVKSEGLHTVCQEAGCPNIYECWEDREATFLIGGSQCTRRCDFCQIDTGKPAEFDRDEPRRVAESVARMGLRYSTVTGVARDDLEDEGAWLYAETIREIHRQSPGTGVEILVPDFSGDPELLGEVFGARPEVFAHNVETVPRIFKRIRPAFRYERSLDVIAQGRAAGLITKSNLILGMGEERQEISQALQDLHDAGTDIITITQYLRPSPRHLPVARWVRPDEFVELRDEAEAIGFLGVLAGPLVRSSYRAGRLWAQSMRAKGRTVPEELRHLADASLGFAQAVS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATIF1_PIG
Sequence: MAATALAVRSRIGAWSVWAMQSRGFSSDTPEGVRSGAGAVRDAGGAFGKKEQADEERYFRARAREQLAALKKHHENEISHHVKEIERLQKEIERHKQSIKKLKNDDDD
What is the function of this protein?
Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix.  Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase (By similarity).  Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme (By similarity).
What are the official names of this protein?
ATPase inhibitor, mitochondrial, ATP synthase F1 subunit epsilon, Inhibitor of F(1)F(o)-ATPase, IF(1), IF1.
What is the protein family that this protein belongs to?
Belongs to the ATPase inhibitor family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SSRP_BORA1
Sequence: MSIIDNRKASHDYFIEDRYEAGLVLQGWEVKSIRAGRVQLKESYVIVRDGELFLLGMHVSPLPTASTHIHPDAMRTRKLLLKAEEIHKLIGKVEQRGFTLVPLNLHYKNGRVKLDFALGRGKKLYDKRDTSREKDWLRERERVMKHDTRRRSD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: DXR_RHOPT
Sequence: MSPVPLKNAERAHSGVRTVSVLGATGSIGDSTMDLIRAEPERYRVEALTGNANVAGLAKLAKEFNARFVAVADPARLGELRAALAGTDVACGAGESAVIEAAARPADWVMAAISGAAGLKPALAAVDRGTTVALANKECLVCAGDFFMSRATAAGAQILPADSEHNALFQALASGNRHELTRVIITASGGPFRTWAAADIEQATLAQALKHPNWSMGQKITIDSASMMNKGLEVIEASYLFALSPDEIDVLVHPQSIVHGLVEFADRSVVAQLGAPDMRIPIAHCLGFPDRITGRAAKLDLAKIGQLTFEAPDFTRFPGLRLAYDALRTGNGATTVYNAANEVAVAAFIAQKIRFGAIARLVEDTLNSWVRAGNQAPLGSADDAIALDQQARNLAATLLPQIAAKAS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: YDDE_BACSU
Sequence: MRLKTPMKAIHKNLLLTRTGDVWAYYRIKSNSIPMQNKEKVESYKKKWQHLFEEITSYEDFHLMMYPSEYELEKRFKDLETDIAADAMDVARYYNEETVRLLEQRLGRLTKYDFILGVKLKSSLVNISVELKDNILSFFNTATDTVVKMLGWEQNVSTSFFEKYEEVEETLANIMASVRGERLSETEMTYINRYHFVRGLKHQTNEESEIKDVRSITNTIIDPTDPSVLHLHSDQDEGYSAFVVIDEFLHNMSESDLFYEAQSLPFPVEVQMKIQTESKSITKPALNLKRQQLKEEQKEQQSTGDRSDVSTVTSATMIRHLQDEIKKEDVHVMNWLSVIVVHGKTKKECVGKATIVKRHLKGAGITCRLPVADQLNLFYKMLPGEKLDITDKNWIQKTTQDGVAESLFAVNSDIGSKIGFFLGWVDRFQEHTDLESAIMSSRDFVLFHPFLANQQLKGSKTRSPHCLITGDTGNGKSYLAKLIFNYISMLNIKSLYIDPKKEMRKWIQRVLNDEYIRENFPLYIAHLEKYNYITLDHENTHNWGALDPISFLPPMKAKELVQVIFEQVYDFKGKDDINTAFLRATSEVIDAKQKGEQVGSLDIIRKMQSHPEEAVQKAGDYLNEVVSDSILKLCIHDGSNPALSLEKRITILEVENMDLPDHAERLENYTISQLKSSAVMFALGKFCELFGMNQDEQTVEFIDEAWIFTTSQQGKKVERQMRRIGRSYNNAEYFISQSTKDALKEEDSGNFGVAFAFDEPNEREEVLKWMNMEVTKDNKKMMESMFQGQCLFKDYYGRTSKISIECLFEEWQGALKTVEKKAVAYAEEKYL
What are the official names of this protein?
Uncharacterized protein YddE.
Protein: PTH_SULIK
Sequence: MVKMVIVVRSDIKMGKGKMAAQVAHAAVTLVISIINSNNSRWKEWLNEWLQQGQPKIVVKANSLDEIILRSKKAETMNLPFSIIEDAGKTQLEPGTITCLGIGPAPENLIDPITGDLKLL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK2_LOBMA
Sequence: MAINLYKTSTPSTRNGAVDSQVKSNPRNNLIYGQHHCGKGRNARGIITVRHRGGGHKRLYRKIDFRRNAKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPVTPWGYPALGRRTRKRKKYSETLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AROB_MYCLE
Sequence: MTNIDAPVTVQVAVDPPYPVVIGTGLSDQLDELLANRHRVAILHQPVLTQTAEAIRSHLAGKGVDAHRIEIPDAEAGKDLSVMDFIWEVLGRIGIGRKDALVSFGGGAATDVAGFAAATWLRGVSIVHVPTTLLGMVDAAVGGKTGINTEAGKNLVGAFHQPLAVLADLATLETLPRKEIASGMAEVVKAGFIADPIILDLIEADPQASLDPMGGVLPELIRRAVTVKAGVVSADEKESELREILNYGHTLAHAIERRERYEWRHGAAVSVGLVFAAELARVAGRLDDATAQRHHTILTSLGLPVSYDADALPQLLEYMAGDKKTRAGVLRFVILDGLAKPGRLVGPDPGLLVTAYAGLSA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_CAMJJ
Sequence: MEFKLKHKDGMARVCEITTAHSTFLTPVFMPVGTVGAVKSLDANDMKNELDAKIILANTYHMYLRPTSKVVKDFGGLHGFTKFDRSFLTDSGGFQAFSLSKNSKHFNEGIEFKSHIDGSHHLFTPKSVLDTQYDFNSDIMMILDDLVALPATKERVKISVDRTILWAKEAITYHKSMQNKGIGIGQNIFGIIQGGTDYEERKRCALSLNEMPFDGLAIGGLSVGEENALMYETVQNLNPYLDENRPRYLMGVGTPEDLVENVERGVDMFDCVMPTRNARNGTFFTSFGKFNIKKAEFINDHEAIDPACSCYTCRNFSRGYLNHLFKAKELTFFRLASLHNLHYYLELARKMREAILNNSFTQFKRNFYHLRGK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: YCF24_GUITH
Sequence: MSDDLSKRSLRELVSQPYKYGFHTDIENEEFPKGLDEDIIKEISKLKCEPSYMLDFRLKSYILWKKMSLPEWACLTYLNINYQDIVYYSAPKNSTKLDSLEDVDKKILETFDKLGIPLNEQKKLANVAVDAIFDSVSVGTTFKQELSNVGVLFCPLSEATNKYSTLVEKYLGSVVPIGDNYFAALNSAVFSEGSFCYIPPNVKCPLELSTYFRINNENSGQFERTLIIADFNSYVSYLEGCTAPMYDKNQLHAAVVELIALENAEIRYSTVQNWYSGDTNGKGGIYNFVTKRGLCAGKSSKISWTQVETGSAITWKYPSCILVGEDSVGEFYSVALTNNYQQADTGTKMIHVGRGSKSRIISKGISAGYSKNTYRGQVKININALGSINNSQCDSMLIGPYSQANTYPYIQVSNAMSRVEHEASTSKIEEEQLFYFLQRGISVEQAISLLISGFCRDVFVKLPMEFAVEADKLLSVKLEGTVG
What are the official names of this protein?
UPF0051 protein ycf24.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COAD_SYNPW
Sequence: MKALYPGSFDPLTLGHLDLIERGASLVDELVVAVLQNPGKSPAFSLEQRLRQITASTEHLGNVSVISFDGLTVACAKEQGTRLILRGLRAMSDFEYELQIAHTNRSLAPEFETVFLTTSAHYSFLSSSVVKEVARFGGAVDHMVPRVVAEDLARFFNSAFAPPSR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_METFK
Sequence: MKKKVIVGMSGGVDSSVAALLLKEQGYEVVGLFMKNWEDDDTDEYCPAKQDLIDAAAVADKIGIELEAVNFSKEYKERVFANFLEEYSAGRTPNPDILCNSEIKFKAFLDHAMALGGDLMATGHYAQVREKNGLFQLMKADDGTKDQSYFLYRLNQAQLSKTLFPLGHLLKREIRDIARRAGLPTSEKKDSTGICFIGERPFQEFLSRYLPRAPGEIQTPEGKVVGQHHGLMYYTMGQRQGLGIGGSKDSNGEPWFVAGKDMQRNVLIVVQGHDHPLLLNDGLIADNLHWIAGEEPKTHWVYAAKTRYRQPDAPCEIDRLDSGTAEIRFGHKQWAITPGQSVVVYESNVCLGGGIITSAL
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.