PharMolix/UniProtQA huggingface dataset:
Protein: SECD_MAGMM
Sequence: MRQQPRWKLYLVVLVALGSIYYALPSLLGGNLPSWMPNKVIHQGLDLQGGLYLLYDVKVEEAIKQAGNNMVDSARNLLRKERQRYRGIEQVGADQVVIRLTPNSDTERMLSVLKDELRESKVEHFQPEAQIRLTLGEAEKVEIRKFAVDQAIEIIRNRIDAFGVSEPSIQKQGERRIIVQLPGIKNPDRAKGLIGRTARLDFKLVNEKGDLNRALEGQVPADSELMYEERSANQGGKSAYPLLVFKRTILSGQHIQNAQTTFNEYNEPIVSVKFDAVGGRKFSQITGEHIKERLAIVLDGKVQSAPVIQDKIAGGRATISGSFTREEAHDLAIVLRAGALPAPLVILEERTVGPTLGADSVAQGLNSVLIGGVLVVLFMVLYYKGFGMLANLAVVLNVTILVSLLALMQATLTLPGIAGAVLLLGMAVDANVLIFERIREELRLGKSPLAAIDHGYSKAFSTILDANITTLITAVILYQFGTGPVRGFAVTLSVGLLASMFTAIFVTRVVLAEVVKNRRLKTLSI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLGB_STRA1
Sequence: MSNKDELYTFGIGENFHLQNYLGVHSENGSFCFRVWAPNAENVQVIGDFTDWRNRPLQMNKNQAGVWEANSLDAREGDLYKYLVTRKGGQVVEKIDPMAVYMERRPGTASVIKVLRNKKWEDGLWMGRRKRLGFQKRPINIYEVHAGSWKKDDFGHPMTFSQLKDYLIPYLVEMNYTHVEFMPLMAHPLDMSWGYQLMGYFAFEHTYGTPEEFQDFVEACHKNNIGVLVDWVPGHFIQNDDALAYFDGTATYEYQNHDRAHNYRWGALNFDLGKNQVQSFLISSALFWIEHYHIDGIRVDAVSNMLYLDYDEGPWEANQFGDNRNLEGYHFLRKLNKVIKERHPNVMMIAEESTASTPITKDLESGGLGFDFKWNMGWMNDILRFYEEDPLYRQYDFNLVTFSFMYIFNENFVLAFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNLYAYQMCHPGKKLLFMGSEFGQFLEWKYNDQLEWENLNDDMNQKMQRYTKQLNQFYKDHKCLWRIDDSFDGLEIIDADNKSETVLSFIRKDDKGDLLLCVFNMTPVERPNFTIGVPQAGIYEEVLNTEMEEFGGVWKNHNPVTKTQVATWKDYDHTLSFTLPALGASVWRIKRRLRK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: CDD_MYCTO
Sequence: MPDVDWNMLRGNATQAAAGAYVPYSRFAVGAAALVDDGRVVTGCNVENVSYGLTLCAECAVVCALHSTGGGRLLALACVDGHGSVLMPCGRCRQVLLEHGGSELLIDHPVRPRRLGDLLPDAFGLDDLPRERR
What is the function of this protein?
Recycles cytidine and 2-deoxycytidine for uridine and 2-deoxyuridine synthesis, respectively.  Catalyzes the hydrolytic deamination of cytidine and 2-deoxycytidine to form, respectively, uridine and 2-deoxyuridine (By similarity).
What are the official names of this protein?
Cytidine deaminase, CDD, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: NACA_CRYNJ
Sequence: MSIENLHIADETEIPAGATVELHSRPERKARKALEGLGLKRVQGIQRVTLRRARNVLLVVSSPEVYKSPGSDCYIVFGEAKVEDPNSAAQLQAQAQLAASSQAAQQAHAHGGFKEGVPKSLEELMQDAPSTDSSAPAPSGEATDASASGDFKVSDEEIQLIVAQTGVDEAKAREAYISEKGDLINAIMKLQ
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  EGD2 may also be involved in transcription regulation (By similarity).
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: ATP5S_HUMAN
Sequence: MCCAVSEQRLTCADQMMPFGKISQQLCGVKKLPWSCDSRYFWGWLNAVFNKVDYDRIRDVGPDRAASEWLLRCGAMVRYHGQERWQKDYNHLPTGPLDKYKIQAIDATDSCIMSIGFDHMEGLEHVEKIRLCKCHYIEDDCLLRLSQLENLQKTILEMEIISCGNITDKGIIALRHLRNLKYLLLSDLPGVREKENLVQAFKTALPSLELKLQLK
What is the function of this protein?
Involved in regulation of mitochondrial membrane ATP synthase.  Necessary for H(+) conduction of ATP synthase.  Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
What are the official names of this protein?
ATP synthase subunit s, mitochondrial, ATP synthase-coupling factor B, FB, Distal membrane arm assembly complex 2-like protein, Mitochondrial ATP synthase regulatory component factor B.
What is the protein family that this protein belongs to?
Belongs to the ATP synthase subunit s family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: RRP14_YEAST
Sequence: MSNSLEERLRANSSAFDGLLALIPAKYYYDEKSQEQWKAKKKTKEQSKNDKLKKLDPEQRDDETSSTLEVMKKKEKDAKPVVLPGEKFKHMKMQKQKEATSKVEGDSDLNVEVNDPMIIAPDEDEEEEEDIKVIFDDEGNEIPLESKKDTTEPDRSVEKKSITEEEKLQRKKNLEALRSKLQAKISDMKSKRKAPGSREAILAQRKRKEELKKRKRLESEQEQDQDEIASDSDMEDIDSDLENNSKKRFKKGKKDSEINADGVMFQNIIFDDGARATSDLQRLRKAGRTKGPAKNDVKSHLKLLEAKKNKMEAKDELEQIKQKEKEKWQKAMLQAEGIKIRDDEKLLRKAIKRKEAQKRKSAIEWSERKRVVEDTISERQKRREENLRIRKDNKGKKRNKQEKMKRKYVGSAVPKKRAGFEGRLKTGKKKGGPK
What is the function of this protein?
Involved in ribosome biogenesis and cell polarity.  Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in correct positioning of the mitotic spindle during mitosis.
What are the official names of this protein?
Ribosomal RNA-processing protein 14, Ribosome biogenesis protein RRP14.
What is the protein family that this protein belongs to?
Belongs to the SURF6 family.
Protein: NRDI_STAAW
Sequence: MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: FPG_MYCUA
Sequence: MPELPEVEVVRRGLQDHVVGKTMTAVRVHHPRAVRRHEAGPADLTARLLGARISGTDRRGKYLWLTLDAGAPTTGRDDPDAALVVHLGMSGQMLLGGVPRAEHVRISAVLDDGTVLSFADQRTFGGWQLADLVSVDGSVVPAPVAHLARDPLDPLFDVDSVIKVLRGKHSEVKRRLLDQQVVSGIGNIYADEALWRAKVHGARVAATLTRRQLGAVLDAAADVMREALAKGGTSFDSLYVNVNGQSGYFDRSLDAYGREGEHCRRCGAVMRREKFMNRSSFYCPRCQPRPRR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TRMB_SYNC1
Sequence: MTQHMIEIKSPYFLREESLASPADFAAVFGNRNPLVLEIGCGIGDFVTQLASSAPERNYLAIDIYNKGCNKTCNRLEQARLTNVRVMRIEARYLLEQFLATESLAAVYINCPDPWPKKRHLKRRLVNERFLQTLLHYLQPGGELFFSSDVADYAHAVTAHLNQIKGYENRLPVPVALDMAGYPLSKYMRRFLAQGQSIHFIHHRRNPQHTCETAAPQPVHRGFRTAWSANNG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ESA1_SCHPO
Sequence: MSNDVDDESKIETKSYEAKDIVYKSKVFAFKDGEYRKAEILMIQKRTRGVVYYVHYNDYNKRLDEWITIDNIDLSKGIEYPPPEKPKKAHGKGKSSKRPKAVDRRRSITAPSKTEPSTPSTEKPEPSTPSGESDHGSNAGNESLPLLEEDHKPESLSKEQEVERLRFSGSMVQNPHEIARIRNINKICIGDHEIEPWYFSPYPKEFSEVDIVYICSFCFCYYGSERQFQRHREKCTLQHPPGNEIYRDDYISFFEIDGRKQRTWCRNICLLSKLFLDHKMLYYDVDPFLFYCMCRRDEYGCHLVGYFSKEKESSENYNLACILTLPQYQRHGYGKLLIQFSYELTKREHKHGSPEKPLSDLGLISYRAYWAEQIINLVLGMRTETTIDELANKTSMTTNDVLHTLQALNMLKYYKGQFIICISDGIEQQYERLKNKKRRRINGDLLADWQPPVFHPSQLRFGW
What is the function of this protein?
Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A. Z (PubMed:16199868).  Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac (By similarity).  The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation (PubMed:18505873, PubMed:33723569).  The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination (PubMed:33723569).  Recruitment to promoters depends on H3K4me (By similarity).  Also acetylates non-histone proteins (By similarity).  In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively (PubMed:29192674).
What are the official names of this protein?
Histone acetyltransferase mst1, Protein 2-hydroxyisobutyryltransferase mst1, Protein acetyltransferase mst1, Protein crotonyltransferase mst1.
What is the protein family that this protein belongs to?
Belongs to the MYST (SAS/MOZ) family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to pericentric heterochromatin (PubMed:20299449). Following DNA damage, localizes to sites of DNA damage, such as double stand breaks (DSBs) (PubMed:33723569).
Protein: PYRDB_METJA
Sequence: MGECMLKTNICGIEFKNPVFLASGIMGETGSALKRIAKGGAGAVTTKSIGLNPNPGHKNPTIVEVYGGFLNAMGLPNPGVDEYLEEIEKVRDELNRMDVRIIGSIYGKDEEEFAEVAKKMERYVDIIELNISCPHAKGYGATIGQNPDLSYDVCKAVKKAVKIPVFAKLTPNVTDIIEIAQAVVDAGVDGLVAINTVRGMAIDIRAKKPILANKFGGLSGKAIKSIGIKVVWDLYENFDVPIIGVGGIMSGEDAIEYMMAGASAVQIGSGVYYRGYDIFKKVCDEIISFLKEENLTLEEIVGMAHE
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTF8_MOUSE
Sequence: MVQIVISSTGAEGLAEWVLMELQGEIEARYSTGLAGNLLGDLHYTTEGIPVLIVGHHILYGKTIHLEKPFAVLVKHTPGKQDCDEPGRGTGTQYLVTALIKNKILFKTRPKPIITNVPKKV
What is the function of this protein?
Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission.  Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DSCC1, RFC2, RFC3, RFC4 and RFC5.  The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated the presence of primed DNA, replication protein A (RPA) and proliferating cell nuclear antigen (PCNA).  The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA.  It also interacts with and stimulates POLH, which is suggestive of a protein network that coordinates DNA repair, recombination and chromosome cohesion reactions with replication fork progression (By similarity).
What are the official names of this protein?
Chromosome transmission fidelity protein 8 homolog.
What is the protein family that this protein belongs to?
Belongs to the CTF8 family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with chromatin during S phase.
Protein: RS22_AGABI
Sequence: MVRISVLNDCLKSICNASRRGKRQVIVRPSSKVVVKFLSVMQRHGYIGEFEIIDDHRGGKIIVQLNGRLNKTGVISPRFNVQHNRIEQWINYLLPSRGIGIIVLTTSSGILDHEEARRKNVGGKLLGYVY
What are the official names of this protein?
40S ribosomal protein S22, Ribosomal protein S15a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: FABV_ERWT9
Sequence: MIIKPRIRGFICVTAHPAGCKANVEKQIEYVTAQGAITSGPKKVLVIGASTGYGLAARISAAFGCNADTLGVFFERAGEENKPATAGWYNSAAFEELATAKGLYANSINGDAYSDAVKQKTIETIRQDLGQVDLVVYSLAAPRRTHPKTGEVFNSTLKPIGKPLTTRGLNTDKETITDVSLEPASAEEIEGTVAVMGGEDWQMWIDALLEAGVLAEGAKTTAFTYLGEKITHDIYWNGSIGEAKKDLDKRVLTIRDTLAAHGNGDARVSVLKAVVTQASSAIPVMPLYLSLLFKVMKEKGTHEGCIEQVYGLFKDSLYNAAPIVDETGRLRADYKELQPEVQDEVSALWPTVTNENLNQLTDFVGYKKEFMHLFGFGLEGVDYDADVNPDVKIKNLVQM
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: UNG_HUMAN
Sequence: MIGQKTLYSFFSPSPARKRHAPSPEPAVQGTGVAGVPEESGDAAAIPAKKAPAGQEEPGTPPSSPLSAEQLDRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELLQKSGKKPIDWKEL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Protein: SODCP_POPTM
Sequence: MASQTLVSPSPLSSPSLLRTSFSGVSVKLAPQFSTLATSNFKPLTVVAAAKKAVAVLKGQSRVEGSSTLHQDERQQQLMFVSLAYTQGFMVFTYMSMVIPQMGVSQQDHILIQQVDTWCSEDEIRHAGDLGNIVANAEGVAECRQSWQIRYHSLRPNSVVGRALVVHELQDDLGKGGHELSLSTGNAGGRLACGVVGLTPV
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn], chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YD83_SCHPO
Sequence: MSFFKKKLSKGKEILSKSNLKTHTSSNASLSIDDLNRFGFSLNPVLWCLDHQQGLLAIVSSTNRIYIYGKQHVQSVIVPDCSTIVHIALCAAYLIVIDSRNTVLSYPLMKHRDLSKPAATYFLKQKVTCTVTDPTIDWVFFGMSDGSVVPWDVTRHCLGKFKVPNLYVPRHEEWRMMGYSYAPVPGKLSPVVSVQIHPKDLGVILIAYPDGVVLYSIRTDEVIRFYELEYAPGSTAAVLSPHNYRRPIVKGIEWSPWGDHFVSYYTDSTFAFWDVDQEYPVQVRNFVDSNIHTYTPMQRNPPKTELEPIRSMRWCCCEDPTVSFILMLGGLPKEAPVKGISLFSYRNLPAKKDVETFAEFFANPNSQRFFPFIDIPPVRDMLVIPSSSPHYNGSHNPKNLLLLSEDNSLSLLDISTGNISNMSLSIPPSLCFLASDFRVIAFQTVTKKVWNQIEDTISVNSHYSCLFGGSPSPGYLKKLDERNLLITSTGLSLSIWDISQGFMNPSLCVNLDFSSVMRKHLTPSAFITTASFSTYNPEFSCADSFGRVIVCKRKNHKENLPAQLANGIYRLDDTLVLEGTLHAQYYIDLKRGRVTLNQMSNIGFVCIGYQDGGITIIDMRGPHILCNTSISELGLERRGKPDPDFLTSAEFVVMNPKGSPSSIYVVTGTYRGMTLLFRIDPSSSGRFSAYFESSRQLDIKNIYKICSLTQDGQIATATGSSLQSVGYPLPQEVFLVYIGDSGISVFNKINNQVGNLDWRKPVCCRAALVLSTVSKHMGSVVCVNSDLSVNWYSLPNLREERKMQLPLDIDKNRLKEGDILGNGDYIFPTLGAHELAFGCVLGSGRTLANLAPMMLITHNASHVPPRPSKSLWNWLLGEQSTSAEELDILLGGENRAESKVHTLETPKVISARPAESVKQPLTPVPSMTSQSAQSYIPPRRQQQQKGFFAQINDHLAQRGNMLGGIENTMDDLEEMSAEWANEIKDSLAGTKKDLILSGLKSYIP
What are the official names of this protein?
Uncharacterized protein C1F3.03.
What is the protein family that this protein belongs to?
To yeast YPR031w.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNLJ_HELPH
Sequence: MIKSQKEYLERIAYLNTLSHHYYNLDDPIVSDAVYDELYQELKAYEEKNPSHIQANSPTQKVGATATNPFNKNPHLMRMWSLDDVFNQSELQAWLQRILKAYPSASFVCSPKLDGVSLNLLYHHGKLISATTRGNGLEGELVSANAKHIANIPHAIAYKGEIEIRGEVIISKKDFDALNKERLNANEPLFANPRNAASGSLRQLDSEITKKRKLQFIPWGVGKHSLNFLSFKECLDFIVSLGFSAIQYLSLNKNHQEIEENYHTLIREREGFFALLDGMVIVVNELNIQKELGYTQKSPKFACAYKFPALEKHTKIIGVINQVGRSGAITPVALLEPVEIAGAMINRATLHNYSEIEKKNIMLNDRVVVIRSGDVIPKIIKPLESYRDGSQHKIERPKVCPICSYELLCEEIFTYCQNLNCPARLKESLIHFASKDALNIQGLGDKVIEQLFEEKLIVNALDLYALKLEDLMRLDKFKIKKAQNLLDAIQKSKNPPLWRLINALGIEHIGKGASKTLAKYGLNVLEKSEAEFLEMEGFGVEMARSLVNFYASNQEFIRSLFELLNPRNSDMAEEKQKSSSVFNNKTIVLTGTLSKPRQEYAQMLENLGAKISSSVSAKTNFLIVGENAGSKLALAQKHGVSVLNEEELLKRLKELD
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: KITH_PHOPR
Sequence: MAQMYFYYSAMNAGKSTTLLQSSFNYRERGMRPVIFTAAIDDRFGTGKVSSRIGLEEDAELYNKSDDLWSKLSMMHADTHIDCVLIDECQFLTKEQVYQLTEVVDKLHIPVLCYGLRSDFRGELFDGSRYLLSWADKLVELKTICHCGRKANMVIRQDEAGHAIADGDQVEIGGNDRYVSVCRKHYKEALGR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_XANCB
Sequence: MRVLILGSGVIGTTTAWYLAQSGCEVTVVDRQPASGLETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPTRDLRQLAWLSQMLRNCTAERYAVNKARMVRLSDYSRDCLNELRASTGLEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQYGVPYELLSPAQIAQYEPGLAGGGAQMAGALHLPEDQTGDCRLFTQRLADLATQAGVQFRYGQQIERLEHAGGEITGVQIDGRLVTADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDERIRVGGMAEVAGFDLSLNPRRRATLEMVVNDLFPGAGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQGRTPEIDTEGLDVFRYLSTRSTRPHREAA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: Y2265_YERPS
Sequence: MSEPLKPRIDFEQPLQSLDEPVLKSAQAFDEQAAEKFYPAAPELDAEDEEGRVEGLVNAALKPKRSLWRKMVTAGMVILGASVIAQSVQWVNQAWQQQDWIALGATTAGGLIILAGVGSVVTEWRRLYHLRQRAEERDIARALLVSHGVGQGRVFCEKLARQAGLDQGHPALQRWQASLHETHNDREVVELYAKLVQPALDNQARAEISRYAAESALMIAVSPLALVDMAFIAWRNIRLINRIAALYGIELGYFSRIRLFRLVLLNIAFAGASELVREVGMDWLSQDLAARLSARAAQGIGAGLLTARLGIKAMELCRPLPWLEGDKPKLGDFRRQLMNQLKNTLPKKDKTAH
What are the official names of this protein?
UPF0283 membrane protein YPTB2265.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLGL3_SOLTU
Sequence: MGKKLKYTKFQLRSNVVKPNICMSLTTDIAGEAKLKDLERQKKGDARTVVAIILGGGAGTRLFPLTKRRAKPAVPMGGAYRLIDVPMSNCINSGINKVYILTQFNSASLNRHIARAYNFGNGVTFESGYVEVLAATQTPGELGKRWFQGTAHAVRQFHWLFEDARSKDIEDVLILSGDHLYRMDYLHFVQSHRQSGADITISSLPIDDSRASDFGLMKIDDTGRVMSFSEKPKGDDLKAMAVDTTVLGLSPEEAKEKPYIASIGKVYVFKKDILLNLLRWRFPTANDFGSEIIPASTKEFCVKAYLFNDYWEDIGTIRSFFRANLALTEHPPRFSFYDATKPIYTSRRNLPPSAIDNSKIVDSIVSHGIFLTNCFVEHSVVGIRSRIGTNVHLKDTVMLGADYYETDAEIRSQLAEGKVPLGIGENTRIKDCIIDKNARIGKNVVIANSEGVQEADRSSEGFYMASGITVISKNSTIPDGTVI
What is the function of this protein?
This protein plays a role in synthesis of starch.  It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase large subunit 3, chloroplastic/amyloplastic, ADP-glucose pyrophosphorylase, ADP-glucose synthase, AGPase S, Alpha-D-glucose-1-phosphate adenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Found in the chloroplast in leaf. Found in the plastid in the developing endosperm.
Protein: TOP1_CANAR
Sequence: MSDSEDVALSELSSRNGIKKEDEEMPLAQLNGNGNAKLRKRKHSEKSKDDHKDKKRKKEKKLSKEKVNNKVKDELISAPVTPKKTPKISKTPVSATSSPAPKKEDSVETDEGYKWWEDENFGEGDERWQTLEHNGVLFPPPYEPLPSYVKLYYEGKPVDLPPLAEEVAGYFAAMIETDHAKNPVFQQNFFNDFLQVLKEGGGCNVDIKEFSKCDFSKMAAFFEKQREEKKSMSKAEKQRIKEEKEKLEEPFKTCLMDGRRENVGNFRVEPPGLFRGRGAHPKTGKFKRRVFPEDITLNLGEGAPIPPPPEGHQWGGIRHDKTVVWLAMWRENISDTFKYVKLAANSSIKGISDMKKFETARKLKDHIERIRADYQKMLKDQFMQNRQIATATYLIDIFALRAGGEKGEDEADTVGCCSLRYEHVTLKPPNKVIFDFLGKDSIRFYQEVEVDRQVFKNLRIFKKEPKGPGDDLFDRITPTILNKHLQNYMKGLTAKVFRTYNASKTMQDQMDLISNEGTVAEKVVKYNAANRTVAILCNHQRTVSKNHEQAVKRINDKIRELEWQKIRLKKMILDIDETEKKDNPKYFEELDDLTNDEMNVIVERVIERQKDQAEKKWNRDNEKRKMEKEELLTKADLQEKLDKIEETRKDYLEEIKTGVVRATKGSSVSSLKSKVETVENRIVNTSYQLKDKEDNSEVSLGTSKMNYIDPRLTVVFAKKFNVPIEKLFTKTLRDKFNWAIESTDENWRF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils.  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: PRMA_SHEFN
Sequence: MAWIQLRIHTHRDNADLLGDLLMDQGSLSITYEDGQDEPIFEPKLGETPLWQDTVMIALFDAGTDLAPTIEFLESMPFLGKGFNHKIEQVEDKDWIREWMDSFHPIQFGSRLWICPSWREIPDPTAVNVILDPGLAFGTGTHPTTALCLEWLDSLDLSNQEVIDFGCGSGILAIAAIKLGAKKVTGVDIDYQAIDASKANAERNDVVDKLALYLPEDQPANLQADVLVANILAGPLKELAPLIAEKVKIGGKLALSGLLQEQAQEVSDFYSQWFIMDPVSNKEDWSRLTGIRK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.