PharMolix/UniProtQA huggingface dataset:
Protein: RLME_SODGM
Sequence: MATKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFRPGMTVVDLGAAPGGWSQYVATQIGGKGRIIACDILPMDPMVGVDFLQGDFREPLVLQALLERVGEQKVQVVVSDMAPNMSGTPAVDIPKSMYLVELALDMCRDVLAPGGNFLVKVFQGEGFDEYLREIRSLFTKVKIRKPDASRARSREVYIVATGRKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTRI_MOUSE
Sequence: MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQSGEYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDDKRLVEGKKGVKVENRPFLSKLTFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPGAVSEVNNGTSRRAGCIWLLPLLVLHLLLKF
What is the function of this protein?
Neural cell adhesion molecule.
What are the official names of this protein?
Neurotrimin.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IgLON family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: RS20_SHIDS
Sequence: MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: UCRI_CHLTI
Sequence: MAQTGNFKSPARMSSLGQGAAPASSGAVTGGKPREGGLKGVDFERRGFLHKIVGGVGAVVAVSTLYPVVKYIIPPARKIKNVDELTVGKASEVPDGKSKIFQFNEDKVIVVNKGGALTAVSAVCTHLGCLVNWVDADNQYFCPCHGAKYKLTGEIISGPQPLPLKQYKARIEGDSIIISKA
What is the function of this protein?
Component of the green S-bacteria bc-complex which consists of the Rieske protein and cytochrome b subunit and which appears to lack a cytochrome c1-equivalent.  This complex has a comparatively low redox potential.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, Rieske iron-sulfur protein, ISP, RISP.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PA2A_GLOBL
Sequence: SLMQFETLIMKIAGRSGIWYYGSYGCYCGAGGQGRPQDASDRCCFVHDCCYGKVTGCDPKLDVYTYTEENGAIVCGGDDPCKKQICECDKDAAICFRDNIDTYDNKYWFFPAKNCQEESEPC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2, PA2-II, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BXA1_CLOBH
Sequence: MPFVNKQFNYKDPVNGVDIAYIKIPNAGQMQPVKAFKIHNKIWVIPERDTFTNPEEGDLNPPPEAKQVPVSYYDSTYLSTDNEKDNYLKGVTKLFERIYSTDLGRMLLTSIVRGIPFWGGSTIDTELKVIDTNCINVIQPDGSYRSEELNLVIIGPSADIIQFECKSFGHEVLNLTRNGYGSTQYIRFSPDFTFGFEESLEVDTNPLLGAGKFATDPAVTLAHELIHAGHRLYGIAINPNRVFKVNTNAYYEMSGLEVSFEELRTFGGHDAKFIDSLQENEFRLYYYNKFKDIASTLNKAKSIVGTTASLQYMKNVFKEKYLLSEDTSGKFSVDKLKFDKLYKMLTEIYTEDNFVKFFKVLNRKTYLNFDKAVFKINIVPKVNYTIYDGFNLRNTNLAANFNGQNTEINNMNFTKLKNFTGLFEFYKLLCVRGIITSKTKSLDKGYNKALNDLCIKVNNWDLFFSPSEDNFTNDLNKGEEITSDTNIEAAEENISLDLIQQYYLTFNFDNEPENISIENLSSDIIGQLELMPNIERFPNGKKYELDKYTMFHYLRAQEFEHGKSRIALTNSVNEALLNPSRVYTFFSSDYVKKVNKATEAAMFLGWVEQLVYDFTDETSEVSTTDKIADITIIIPYIGPALNIGNMLYKDDFVGALIFSGAVILLEFIPEIAIPVLGTFALVSYIANKVLTVQTIDNALSKRNEKWDEVYKYIVTNWLAKVNTQIDLIRKKMKEALENQAEATKAIINYQYNQYTEEEKNNINFNIDDLSSKLNESINKAMININKFLNQCSVSYLMNSMIPYGVKRLEDFDASLKDALLKYIYDNRGTLIGQVDRLKDKVNNTLSTDIPFQLSKYVDNQRLLSTFTEYIKNIINTSILNLRYESNHLIDLSRYASKINIGSKVNFDPIDKNQIQLFNLESSKIEVILKNAIVYNSMYENFSTSFWIRIPKYFNSISLNNEYTIINCMENNSGWKVSLNYGEIIWTLQDTQEIKQRVVFKYSQMINISDYINRWIFVTITNNRLNNSKIYINGRLIDQKPISNLGNIHASNNIMFKLDGCRDTHRYIWIKYFNLFDKELNEKEIKDLYDNQSNSGILKDFWGDYLQYDKPYYMLNLYDPNKYVDVNNVGIRGYMYLKGPRGSVMTTNIYLNSSLYRGTKFIIKKYASGNKDNIVRNNDRVYINVVVKNKEYRLATNASQAGVEKILSALEIPDVGNLSQVVVMKSKNDQGITNKCKMNLQDNNGNDIGFIGFHQFNNIAKLVASNWYNRQIERSSRTLGCSWEFIPVDDGWGERPL
What is the function of this protein?
Responsible for host epithelial cell transcytosis, host nerve cell targeting and translocation of light chain (LC) into host cytosol.  Composed of 3 subdomains; the translocation domain (TD), and N-terminus and C-terminus of the receptor-binding domain (RBD) (PubMed:9783750, PubMed:17173035).  The RBD is responsible for the adherence of the toxin to the cell surface.  It simultaneously recognizes 2 coreceptors; polysialated gangliosides and synaptic vesicle glycoproteins SV2A, SV2B and SV2C in close proximity on host synaptic vesicles (By similarity).  The RBD specifically recognizes the N-linked glycan on 'Asn-559' of SV2A, SV2B and SV2C (By similarity).  Isolated HC binds to host synaptosomes, significantly decreases uptake and toxicity of whole BoNT/A (PubMed:19476346).  Binds ganglioside GD1a in vitro (PubMed:21849494).  The N-terminus of the TD wraps an extended belt around the perimeter of the LC, protecting Zn(2+) in the active site; it may also prevent premature LC dissociation from the translocation channel and to protect toxin prior to translocation (PubMed:9783750).  The TD inserts into synaptic vesicle membrane to allow translocation into the host cytosol (By similarity).
What are the official names of this protein?
Botulinum neurotoxin type A, BoNT/A, Bontoxilysin-A, BOTOX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M27 family.
What are the subcellular locations of this protein?
[Botulinum neurotoxin A light chain]: Secreted. Host cytoplasm, host cytosol. SUBCELLULAR LOCATION: [Botulinum neurotoxin A heavy chain]: Secreted. Host synapse, host presynaptic cell membrane. Host cytoplasmic vesicle, host secretory vesicle, host synaptic vesicle membrane; Multi-pass membrane protein.
Protein: STING_HUMAN
Sequence: MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLLNGVCSLAEELRHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWMLALLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTSTMSQEPELLISGMEKPLPLRTDFS
What is the function of this protein?
(Microbial infection) Antiviral activity is antagonized by oncoproteins, such as papillomavirus (HPV) protein E7 and adenovirus early E1A protein (PubMed:26405230).  Such oncoproteins prevent the ability to sense cytosolic DNA (PubMed:26405230).
What are the official names of this protein?
Stimulator of interferon genes protein, hSTING, Endoplasmic reticulum interferon stimulator, ERIS, Mediator of IRF3 activation, hMITA, Transmembrane protein 173.
What is the protein family that this protein belongs to?
Belongs to the STING family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=In response to double-stranded DNA stimulation, translocates from the endoplasmic reticulum through the endoplasmic reticulum-Golgi intermediate compartment and Golgi to post-Golgi vesicles, where the kinase TBK1 is recruited (PubMed:19433799, PubMed:30842659, PubMed:30842653, PubMed:29694889). Upon cGAMP-binding, translocates to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) in a process that is dependent on COPII vesicles; STING1-containing ERGIC serves as a membrane source for LC3 lipidation, which is a key step in autophagosome biogenesis (PubMed:30842662).
Protein: UVRC_ARTS2
Sequence: MADPASYRPQTGEIPTNPGVYRFRDPHGRVIYVGKAKSLRSRLNSYFANPGGLLPKTYAMVHAASSVEWTVVASELESLQLEYTWIKEFKPRFNVVFRDDKTYPYLAVTMGEKFPRVQVLRGERRKGTRYFGPYTAGAIRETMDTLLRVFPVRSCSPGVLKRAQASGRPCLLGYIDKCAAPCVGRVTPEEHRALAEDFCSFMGGEAKRFIGRLEKDMAAAVAELDYERAARVRDDIIALRKVFERNAVVLAEDTDADVFALHEDELEAAVQVFHVRGGRVRGQRGWVVEKVEDFTTPDLVEHLLQQVYGEEGETQGRLPREVLVPEEPSNAAELAQWLAGLRGAKVDIRVPRRGDKAALMSTVRENAEHALKLHKSRRAGDLTNRSLALQELQEALDLPVALLRIECFDISHVQGTNVVASMVVVEDGLPKKSDYRKFSITGAAAVDDTAAMHDVLTRRFRNYLQEKAAQAEAAQLPGHQAALEAMAVASMQDTTTPAPRAKFAYPPNLVVVDGGKPQVNAAARALAELGIDDVYVVGLAKRLEEVWLPDSDFPVILPRTSEGLYLLQRIRDEAHRFAITFHRQKRGKAMTVSALDSVPGLGEAKRKALLAQFGSVKSIRTASAAELATAKGIGPSLADAIVSHFSNGAAASGAEAPSINMTTGEIIET
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_CROS5
Sequence: MVKTVDFSGRPFHFIGIGGIGMSALAYVLAKRQLPVSGSDLRSTHITERLQGVGAHIFSRQEATNLELFNSSPERVLETVSVAVNGTQPSYPNGNGKTFSDSPSLLLQETLPQVICSTAIAHNNSEYAAAKEKGCPIFHRSDVLAALIRDYQSIAVAGTHGKTTTSSLIGYMLLKADLDPTIIVGGEVDAWEGNARIGAKGGYLVAEADESDGSLTKHYPNIGIVTNIELDHPDHYQTLDDVVKTFQIFETQCDLLIGCLDCETVASELTPAITYSLDPSKGADYTVQNVTSNHKGTFAEVWERGNYLGEIRLTIPGSHNLSNALAAIAVGRKLGLNFAVIADALFTFAGAKRRFEQRGQCNGITFIDDYAHHPSEIEATLSAARSKVDGETISRVVAIFQPHRYSRTATFLKEFATCFKDADLVILTDIYSAGEVNLHNISGQDLAEAVENNHSQVIYEPSLKGLPQVIPDLIKPGDLVLFLGAGNLNQIIPEMINTYHTASTQSTANAMVETSINC
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARND_ECO8A
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIEAKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVVRGNIAGREGWLGCQQIAGSR
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: Y1221_YERPE
Sequence: MSTKIHQQAVQPGISQQVSTRLAFFIAGLGMAAWAPLVPFAKARIGLNDASLGLLLLCIGIGSMLAMPLTGVLTAKWGCRAVILLAGAVLCLDLPLLVLMNTPATMAIALLVFGAAMGIIDVAMNIQAVIVEKASGRAMMSGFHGLFSVGGIVGAGGVSALLWLGLNPLTAIMATVVLMIILLLAANKNLLRGSGEPHDGPLFVFPRGWVMFIGFLCFVMFLAEGSMLDWSAVFLTTLRGMSPSQAGMGYAVFAIAMTLGRLNGDRIVNGLGRYKVLLGGSLCSAIGIIIAISIDSSMAAIIGFMLVGFGASNVVPILFTAAGNQTVMPANLAVASITTIGYAGILAGPAAIGFIAQLSSLSVAFGCVALLLLTVAASARAVTR
What are the official names of this protein?
Uncharacterized MFS-type transporter YPO1221/y2967/YP_0917.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KCNS2_RAT
Sequence: MTRQSLWDLSETDVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSVLSILVVLGSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESSPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSLMASLTNMSRSSPSELSLDDSLH
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.
What are the official names of this protein?
Potassium voltage-gated channel subfamily S member 2, Delayed-rectifier K(+) channel alpha subunit 2, Voltage-gated potassium channel subunit Kv9.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.2/KCNS2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2.
Protein: BOSS_BOTBR
Sequence: MVKLVEVLQHPDEIVPILQMLHKTYRAKRSYKDPGLAFCYGMLQRVSRSFSVVIQQLPDELRHPICVFYLILRALDTVEDDMNLPNEVKIPLLRTFHEHLFDRSWKLKCGYGPYVDLMENYPLVTDVFLTLSPGAQEVIRDSTRRMGNGMADFIGKDEVHSVAEYDLYCHYVAGLVGSAVAKIFVDSGLEKENLVAEVDLANNMGQFLQKTNVIRDYLEDINEEPAPRMFWPREIWGKYAQELADFKDPANEKAAVQCLNHMVTDALRHCEIGLNVIPLLQNIGILRSCLIPEVMGLRTLTLCYNNPQVFRGVVKMRRGETAKLFMSIYDKRSFYQTYLRLANELEAKCKGEASGDPMVATTLKHVHGIQKSCKAALSSKELLAKSGSALTDDPAIRLLLLVGVVAYFAYAFNLGDVRGEHGVRALGSILDLSQKGLAVASVALLLLVLLARSRLPLLTSASSKQ
What is the function of this protein?
Produces squalene when coexpressed with SSL-1 and bisfarnesyl ether and a very small amount of squalene when incubated alone in the presence of NADPH.
What are the official names of this protein?
Botryococcus squalene synthase, Squalene synthase-like 2.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DLTC_STRT1
Sequence: MDVKAEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVELESRFDIRVPVSEFGRDDWNTANKIVEGVTELRNA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG10_KLUMD
Sequence: MLTLPEYNEQIPNVRSLLTKWAKVERIQDVQDGLQLDVRLKTDTLLELHIYYDHVYHVPSIKFRLWSLDTEEDISSLRLLTLSDSELRSILNLGTFSVTLSTDMEMKSVYYYINNCDTDANVGSDVEHYLTRWISLYIRIFDLNFVP
What is the function of this protein?
E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy (PubMed:26442587, PubMed:22682742).  Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5 (PubMed:22682742).  ATG12 conjugation to ATG5 is required for proper localization of ATG8 to the preautophagosomal structure (PAS) (By similarity).  Likely serves as an ATG5-recognition molecule (By similarity).
What are the official names of this protein?
Ubiquitin-like-conjugating enzyme ATG10, Autophagy-related protein 10.
What is the protein family that this protein belongs to?
Belongs to the ATG10 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: RL11_PROMS
Sequence: MAKKIVAVIKLALQAGKANPAPPVGPALGQHGVNIMAFCKEYNARTQDKAGFVIPVEISVFEDRSFTFITKTPPASVLITKAAGIEKGSGESAKGSVGNISKAQLEEIAKTKLPDLNCSSVESAMKVIEGTARNMGVSITD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: HEM1_ECOLC
Sequence: MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQILADEVGAEVIALSEIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMAWLRAQSASETIREYRSQAEQVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAPTKSLQQAARDGDNERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: GAL1_MYCBT
Sequence: MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITARSDRADGSARIPLDTTPGQVTGWAAYAAGAIWALRGAGHPVPGGAMSITSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRAENDYVGAPTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRARHRHAGGEYALRRASCERAAADLGVSSLRAVQDRGLAALGAIADPIDARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASHESMREDFAITTERIDLIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGYDEPAVSRTYAAPGAAECC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN148_HUMAN
Sequence: MNIDDKLEGLFLKCGGIDEMQSSRTMVVMGGVSGQSTVSGELQDSVLQDRSMPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQMETHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQIREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESALDKSDLKKDKNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQNQTISPLSTYEESKVSKYAFELVDKQALLDSEGNADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDESTTASILESQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSEVPEVTPSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNQPAFSSIDKQVYATMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHSFPFSGDETNHASATSTQDFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG
What is the function of this protein?
Involved in transcriptional regulation.  Represses the transcription of a number of genes including gastrin, stromelysin and enolase.  Binds to the G-rich box in the enhancer region of these genes.
What are the official names of this protein?
Zinc finger protein 148, Transcription factor ZBP-89, Zinc finger DNA-binding protein 89.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: ZDHC1_DANRE
Sequence: MDVCSKNSNRTAPVSEGGIRRADVPLCSRTNGWSWPPHPFQFLAWLLYLYFAVTGFGVFVPLLPTHWIPAGYICTGITFVCHLFMHLMAVSIDPADYNVRAKSYKGPMPVFDRTKHAHVIENCHCYLCEVDVGPKSKHCSACNKCVASFDHHCRWLNNCVGSRNYWLFLNSVISALLGIVLVVVIASYVFIEFFLDPSKLRSDKHFQQVRNESVVWFVFLPVAPVTTAGPAIPALAGVTIALGLLSALLLGHLLCFHIYLMWNRLSTYEYIVRQRHRQEAGDSRKPPPENDSGVPKLNLIKQQVSYSGTLGYTNPEMEVEDPKAMTSQEGAARYGNGRIRCSSEHMDEEEHLPSVLTEQKASPHPHKHAQKKKRKVRKLAAEVNGDISIDTSTAKGLQKTSAEKESSVAAATVSSSLGQRLPFPAFPLRASLPPLAPVQAAGPPAEYHSDSAESLEEIPVAMARLGSAALAGAQIPTTTATASSSYSSMLQCALPSSAAGHAAPSPQPRTKRKTAARTVSEQRFEMLYHNPSMFMTRESGEPAIPPEESPRAAKRKQTGKKRNTEDAKPSSRVGTSLA
What is the function of this protein?
May have a palmitoyltransferase activity toward substrates like ncdn, thereby regulating their association with membranes.
What are the official names of this protein?
Palmitoyltransferase ZDHHC1, DHHC domain-containing protein 1, Zinc finger DHHC domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus.
Protein: NOC_LISW6
Sequence: MPFSRLFGKKEKNQMDDIVEEGVQRVLELPMDKIFPNQFQPRTVFDQDKIDELARTIRIHGVIQPIVVREMEPDYYEIIAGERRFRAVLSLELEKIPAIIQNLDDEEVAAIALIENLQREELTPIEEAKAYRSLLDMQDVTQEALAQRVGKSQSAIANKLRLLKLPEAVQQAVLNKQISERHARSLLALETEATQVDLLAEIEENHWNVKQTEARIQEILGVKKPTTTKKTKPKRQAISRDVRIAMNTIKQSVTMVKDNGMDLDFKEEETDDFYQITIQIPKKK
What is the function of this protein?
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle.  It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
What are the official names of this protein?
Nucleoid occlusion protein, Noc.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PK81D_PSEFD
Sequence: MALGFLVYLSYTPRIKGNIPAFTPETYPIIGSYKFFTHKLSFWKAAQRASKNGMFSFWLGKNHVVGVSGEAARKMYLENPAMDHIKGVILIGHGPDYIDGRKTKQHGIWLPVMAGNKSYAQKNVLNCQKTAELTKRLPKVTNDVRKAFESVASQGFIINPARMCAVLTWDTATRVFAADELIDVPENRAKLLYYLPILQKTSSCHLLSFPWASYFSLPYWKRKYGREGMRRLVTPIVEARMRIIDPVRADDPLQTFVDNGDSADYMINFLISMIFISAANGCVVSGAMLYSIAHHPELQEKIYQEIKAAANQYAADSSAPLVDQLDSLPVKAWENMSETIDLCYKECIRMWVAFPMGRMNEGTTDIKIPGTDEVVPAGGLCCYNTIDVHYSEKLYPEPLKWDPARFGEGRKEMEQEAHGFMGWGAGRHPCNGIRWAKIQQNMMLAYAFAMYKWTGCHKDGSPNTDFIPPTTALNELAPSLPQNLFLKAEPRK
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of an emodin derivative that may be involved in black Sigatoka disease of banana (PubMed:27388157, PubMed:30735556).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase PKS8-1 (Probable).  The atrochrysone carboxyl ACP thioesterase MYCFIDRAFT_190111 then breaks the thioester bond and releases the atrochrysone carboxylic acid from PKS8-1 (Probable).  The decarboxylase MYCFIDRAFT_34057 then catalyzes the concerted decarboxylation-elimination required to convert atochrysone carboxylic acid into emodin anthrone, which is further oxidized to emodin by the anthrone oxygenase MYCFIDRAFT_34418 (Probable).  The functions of the other tailoring enzymes as well as the final product of the cluster have still to be identified (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase MYCFIDRAFT_204672, PKS8-1 gene cluster protein MYCFIDRAFT_204672.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YSXB_CAEEL
Sequence: MRRGGEPQCDGREFRIASSPAREREDDNETAPPQTSAAQEPLVDCFLGTVPNSCFVRCELI
What are the official names of this protein?
Uncharacterized protein T28D9.11.