PharMolix/UniProtQA huggingface dataset:
Protein: CO1EA_CONGR
Sequence: MKLTCVLIITVLFLTACQLTTAVTYSRGEHKHRALMSTGTNYRLPKTCRSSGRYCRSPYDRRRRYCRRITDACV
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin is very potent on alpha-9-alpha-10/CHRNA9-CHRNA10 nAChR (IC(50)=4. 61-12 nM for the bead isomer (I-II; III-IV), IC(50)=7-16 nM for the ribbon isomer (I-IV; II-III) and IC(50)=22. 7 nM for the globular isomer (I-III; II-IV)) (PubMed:26170295, PubMed:31986036).  The bead isomer also shows a weak inhibition on other nAChRs (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE, alpha-7/CHRNA7, alpha-6/alpha-3-beta-2-beta-3 (CHRNA6/CHRNA3-CHRNB2-CHRNB3), alpha-3-beta-2/CHRNA3-CHRNB2, alpha-2-beta-2/CHRNA2-CHRNB2, alpha-6/alpha-3-beta-4 (CHRNA6/CHRNA3-CHRNB4), alpha-4-beta-2/CHRNA4-CHRNB2, alpha-4-beta-4/CHRNA4-CHRNB4, alpha-2-beta-4/CHRNA2-CHRNB4, alpha-3-beta-4/CHRNA3-CHRNB4) (PubMed:26170295, PubMed:31986036).  The toxin blockade is voltage-dependent, and its binding site does not overlap with the binding site of the competitive antagonist alpha-conotoxin RgIA (PubMed:26170295).  The toxin inhibits Sf9 cell growth (PubMed:22825834).  Both the bead and ribbon isomers relieve pain effects in the rat chronic constriction injury (CCI) model of neuropathic pain, and in the acute pain model of tail flick test, but have no effect on motor performance (PubMed:26170295, PubMed:26706456).
What are the official names of this protein?
Alpha-conotoxin GeXIVA, Alpha-O-conotoxin GeXIVA, Conotoxin Ge14.1, Conotoxin GeXIVAWT.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CRGB_MACFL
Sequence: MGKITFYEDRNFQGRCYECSGDCADLQAYFSRCNSVRVESGSWVLYEQPSYKGCQYFLKRGEYSDYRQWMGTSDSIRSCRLVPRHEGSYRMRIYERENCAGQMMEFTEDCPSVRDHFHQKDVLSCNVLDGYWVLYEQPNYQGRQYFLRPGEYRRHSEWGAGTAVLGSFRRAVDNP
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin B, Gamma-B-crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: RL11_DESOH
Sequence: MAKKVTGQIKLQVTAGKANPSPPIGPALGQHGVNIMDFCKAFNARTADQEGMIIPVVITVYADKSFSFITKTPPAAILLKKAAKIAKGSAVPNKDKIGKVSMQDVEEIARLKMPDLNATDLDAACRIIQGTARSMGIEIVQ
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: KPTA_CLOPS
Sequence: MKNNDSKISKYISLILRHKPEEIGLKLDEHGYLVVLDLIEGINKSYEGFSMDDLERIVREDSKGRYSFNEDKSKIRANQGHSIKVDLGLEEIKPPKVLYHGTGRKYLESILKNGLIKKERQYIHLSKDRETASIVGKRHGDLVILEVDSESMFNDGIKFYLSKNNVWLCNYVPKKYIKELNLEEVF
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: DYL_DICDI
Sequence: MSSNKYIINVKNADMPDFMQQDATECTIKAFEETNIERDIAMIIKKEFDKKYSPTWHCIVGKSFGSFVTHETKNFIYFNINKHSVLLFKAG
What is the function of this protein?
Acts as a non-catalytic accessory component of a dynein complex.
What are the official names of this protein?
Dynein light chain, cytoplasmic, Dynein light chain LC8-type 2.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SCBM1_MEGVE
Sequence: TTEEVPLNPEPRTECDSDNCAAGERPYAPNIAIENGDTIIAIGVVADVMFVIDXNCPLYCNFCIVADVMFVIDLVYEVGSFEALQQAIDNIMFT
What is the function of this protein?
Hydrolysis of sulfocarbamoyl esters of paralytic shellfish toxins.  Does not hydrolyze the carbamoyl esters of paralytic shellfish toxins.  Ester hydrolysis is significantly affected by the stereochemistry of sulfate esters at C-11 of the substrate toxin.
What are the official names of this protein?
Sulfocarbamoylase-1, Sulfocarbamoylase I.
Protein: YTFP_ECO57
Sequence: MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGAVPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKLIESGDWLDRDK
What are the official names of this protein?
Gamma-glutamylcyclotransferase family protein YtfP.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: RPOB_PORCN
Sequence: MSSHNPTQRVNFASIKNPMEYADFLDVQLKSFKDFLQLDTPPEKRKKEGLYKVFAENFPIHDTRNNFVLEFLDYYIDPPRYTLDECISRGLTYNVPLKAKMKLYCTDPEHEDFETVIQDVYLGPIPYMTESGTFIINGAERVVVSQMHRSPGVFFSESVHPNGTKLFSARIIPFKGSWIEFATDINNVMYAYIDRKKKLPVTTLLRAIGFETDKDILNLFGIAEEVKVSKSTLKKYYGRKIAARVLNSWIEDLVDEETGEVVSMERYDVIVDRDELLTEDNVDQIIESGAKNILITKDDSELGLDYSVTTNTLQKDPSNSEKEAVYHIYKQLRNQDPVDDASAREVINSLFFSEKRYDLGDVGRYRINKKLGINIDEETKVLTTEDITAIIAHLVELMNSKQVVDDIDHLSNRRVRTVGEQLYNQFGIGLARMARTVRERMNVRDNEVFTPIDLINAKTISSVVNSFFGTNALSQFMDRTNPLAEITHKRRLSSLGPGGLSRDRAGFEVRDVHYTHYGRLCPIETPEGPNIGLISSLCVYAKINDLGFISTPYRKVVDGKVDFSENGVEYYTAEAEDDKTVAQGNAPLDENGKFIKDAVYARYGSDFPVVSPSEIDLMDVSPIQIASIAASLIPFLEHDDANRALMGSNMMRQAVPLIHSDAPIVGTGVEQKLVHDSRTQIVAEGAGTVEFVDASVIKIRYDRSEDDTFVSFEDNLKIYNLPKFRKTNQSTTIDLRPICRKGDRVEKGDILTEGYSTENGELALGRNVQVAYMPWKGYNYEDAIVLNERMVREDIFTSVHVDEYILEVRETKRGLEELTSDIPNVSEEATKDLDDRGIIRVGARVHPGDILIGKITPKGESDPTPEEKLLHAIFGDKAGDVKDASLKANPSLSGVVIKTHLFSKAMHSKKDKGGVREIVKKLDEEMEEKLAELRELMLKKLIQLTDNKLSNGIRNFEDTEIVPKGVKLTPAVCSKIEFGEVAIFNWTGDEHTDELVAKLISNYLRKAKEIESEYRRKKFDATIGDELPNGIIQIAKVLIAKKRKIQVGDKMAGRHGNKGIVSKIVRQEDMPFMEDGTPMDLCLNPLGVPSRMNLGQIFELSSMGSRRLDVKFATPIFDGASLDDLDQWTDKAGIPRYGKTYLYDGGTGEQFDQPATVGVTYFLKLGHMVDDKMHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHVLQEMLTIKSDDVVGRSKAYEAIVKGAPMPTPGIPESLNVLLHELKGLGLSFCME
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: IFR_CICAR
Sequence: MASQNRILVLGPTGAIGRHVVWASIKAGNPTYALIRKTPGDINKPSLVAAANPESKEELLQSFKAAGVILLEGDMNDHEALVKAIKQVDTVICTFGRLLILDQVKIIKAIKEAGNVKRFFPSEFGLDVDRHDAVDPVRPVFDEKASIRRVVEAEGVPYTYLCCHAFTGYFLRNLAQFDATEPPRDKVIILGDGNVKGAYVTEADVGTYTIRAANDPRTLNKAVHIRLPHNYLTSNEVVSLWEKKIGKTLEKSYISEEKVLKDINVSTFPHNYLLALYHSQQIKGDAVYEIDPAKDAEAYDLYPDVKYTTADEYLDQFV
What is the function of this protein?
Reduces achiral isoflavones to chiral isoflavanones during the biosynthesis of chiral pterocarpan phytoalexins.
What are the official names of this protein?
Isoflavone reductase, IFR, 2'-hydroxyisoflavone reductase, NADPH:isoflavone oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: GLEM_HUMAN
Sequence: CEGHSHDHGA
What are the official names of this protein?
Erythrocyte membrane glycopeptide.
Protein: NUOJ_BUCAI
Sequence: MEFVFYVCSFAAVVSTFFVIIQKNAVYSLVYLIISLLSIAGVFFSLGAFFAGSLEVIIYAGAIIVLFVFVIMMLNISDKYNLEEAHYLKPRFWIGPSILSLILLLSMTYAIFFLRDKKIDGFLIDSKIVGINLFGPYVFLVELSSILLLSALVVIFHIGTEKNVDKNKVL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit J, NADH dehydrogenase I subunit J, NDH-1 subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y533_BACC2
Sequence: MISQSTLFLFILLIIGLIAKNQSLTVAIGVLFLLKFTFLGDKVFPYLQTKGINLGVTVITIAVLVPIATGEIGFKQLGEAAKSYYAWIALASGVAVALLAKGGVQLLTTDPHITTALVFGTIIAVALFNGVAVGPLIGAGIAYAVMSIIQMFK
What are the official names of this protein?
UPF0756 membrane protein BCG9842_B0533.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y5634_DICDI
Sequence: MAPRKKAVTKKKTVEKSPPIEEEIIEEPVDEIVESDGDDKKNKKKGKRKSSKKSKKEKEENVEEEEQDQEEEEEGNKKQKEENDADKKSRKHDEHRKKRDSKNRRSHSKSDENEEGEEDDEERRKKRRRRKHREKRKKNGNKEEEEEEEQDDEHEDQNVEEDEEDVNVEKQKQQQQQSDFDEEEKEEEKEEEEEEEQIEIKKRSKKRNSIDSGRKDKSKKRKSKKKKRGQNDDDDDDDDNDDDDDDQDEEKEYEQDEDVNQESIVSEKEEEEDEEKQSQGSEDEEKQSENERRNDQDYTDRERERNRSRDRDSRDYSSRSDHRDYRDRDRDRSRDRDRDYRDSRDYRDRDRDYRDRDRDHYSSGGSSSSSRDHRDHRDRDYRDRDRDHRDRSRDRDRDHYSSSSGSSSNRRSRDRDNDSKRDEKSSSSNNSNNSTSTTSNNNASSNNVKIVQPPKENFFSNYRAIQSSIIPTHNKSKFGERILSIAPTEPPPNFQIPLSKPYRDDSLQQNNDNNNNSSNNNSNNSNNNFNNDNNPYNNSNNYNMNNSNTSPYNNSNNSNSNSSYYNDNDYNNNNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNFNNSNSNSSESKPNYFNNLSNVFNQITKPLENYKNNGKNENNNNNNNKNKNEDEKRIDLVQTKLSLKSSKSTPQTYNEKEFKVQISNIVVKKLKKYYKTKITTKEDFQYLGKKFTDFVITKERGNQTINKDSEKKIEKVIDNYFEKKEVYDRKKDKDYKKDDGDKLINSSIDISNDSNLSESSITITSTSTSTSTSALTSPKTTGTTTSTITTVTSTSTSSIENTKILVDDEKFKTNIQNETSKESNSI
What are the official names of this protein?
Uncharacterized protein DDB_G0283697.
Protein: UVRC_BORBU
Sequence: MKENLTNLFEKVIKLPTTSGCYKMLNENKKILYIGKAKNLRSRVKSYFLEKNSHKIKILMKNVKSIEVITTNSEYEALLLECNLIKTHKPDYNVKLKDGKGYPMVRITHEKYPRIFKTRKIINDKSEYFGPFTNVKKLDQVLDFINKTFKIRKCKKKSNAPCLYYHMGQCLGVCYKENLEKEYQKELDKAKSILNGNISEISSQIDIKLKHAIQKEDFETAIKLKEIRNSLIEINQIQIVTKTNNLNIDYVHVHPGENVNTIIVLKYRNGKLVERDANFDESICKENELILQFLIQYYTSINMIVPDKIHIFLKDIDTKNVEKLINEIKNTKTEIIYKETEEILKIMEMAISNAELSLREYENKSTKALESLKIVLEMDKLPKIIEGFDIAHLKGQETVASMVTFKMGMPFKENYRLYKLNSLLKGEIDDFKAIKEVISRRYSEIINNNLELPNLILIDGGKGQLNAALSILKGLKIENKVKVCSLAKKQETIFLTTNKKGINLPQGHPALRILQNVRDEAHRKANGFNKKRREKITLLYTKIHGIGEKTAQKILKSIGTYKDILPLSENEISEKIKVNVQLAKRIKEFAIKENSIKNNNQDK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS72_PHYTB
Sequence: ALWKDVLKKIGTVALHAGKAALGAVADTISE
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Dermaseptin-7.2TR.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SSG1_AEGTS
Sequence: ATGSGGMNLVFVGAEMAPXXX
What are the official names of this protein?
Granule-bound starch synthase 1, Granule-bound starch synthase I, GBSS-I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast. Note=Amyloplast or chloroplast, granule- bound.
Protein: RL17_ALTMD
Sequence: MRHRKSGRQLNRNSSHRQAMFKNMAGSLVKHEVIKTTLPKAKELRRVIEPLITMAKEDSVANRRLAFARTGDKEVVGKLFNELGPRYEARPGGYTRILKCGFRAGDNAPMAYVELVDRPVVEAEEEAVEATEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SUB3_PLAF7
Sequence: MINRQYFIWYIFIFNIINKIYFENIRYVKNYEVVIRKKKNIERGIGNDFAFIRRYYKSRLLSDVSYKNNSIKGKNRVDKEGDIKKYDNNDDNKMDNSYDYKNKSIKENETKIRKEQVISLDKRYNRNINEKEEIKKKIKDIQRKRLIIYFKQDNTILSSRNYKHIFMKVLSSCGHIEKLTFINFYLYEFPKSINNEDMLLKICLRLLESRRINVENDNQISHTVQMKSYNNNNNKWDNINSKNNCIYQIKDKIKDLPNVSPSASTFTSISTSPYTLKLRDRNKYANDKNHIFKINHSNKHKNNNNNNNNNDYHNNNKSNYHSHSSAKCQTQRLNKKMIGTNILDGYDIIQMEEGLNLSHNYELNDVNVCIIDTGIDENHIDLKDNIIEKKTFMKHSYKKYNIDGINNIESDNIDGINNIESDNIDGINNIESDNIDGINNIESDNIDGINNIESDNIDGINNIKSSDNIKSSDNIKSSDNINSSDNIKSSDNNNVHTMLRNKLYLKKKKECSNYNTSNDGHGHGTFIAGIIAGNSPKGKKGIKGISKKAKLIICKALNNNNAGYISDILECFNFCAKKKARIINASFASTTHYPSLFQALKELQDKDILVISSSGNCSSNSKCKQAFQECNLNIQKLYPAAYSADLNNIISVSNIIQQSNGNIVLSPDSCYSPNYVHLAAPGGNIISTFPNNKYAISSGTSFSASVITGLASLVLSINSNLTSQQVIELFKKSIVQTKSLENKVKWGGFINVYDLVRFTIDSLPKDKDE
What is the function of this protein?
Serine protease which may cleave PFN/profilin.
What are the official names of this protein?
Subtilisin-like protease 3, PfSUB3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEFA2_ORNAN
Sequence: MRTLSLLLALLFLAAQTLAQPIDEGAEEVITEEPEITETQDPTTIMLIERGIGGDSTDATRSTITCYCRSRCRMLEKNSGTCRSSNCTYTLCCKKTS
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Defensin-A2, DefA2, OaDefA2.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS7_BURPS
Sequence: MRVAQVVRNTSETQISVKIDLDGTGRQKLATGVPFLDHMLDQIARHGLVDLDIEAHGDTHIDDHHTVEDVGITLGQAVAKAVGDRKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARIGTFDVDLSIEFFRGFVNHAGVTLHIDNLRGVNAHHQLETVFKAFGRALRMAVELDERAAGQIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_METFK
Sequence: MKGNLFIITAPSGAGKTSLVRALLDGDEHIKLSVSHTTRKPRPGEEDGVHYHFVEEARFVELLNHGDFLESAQVHGAYYGTSQSTVNSALAEGYDLILEIDWQGAQQVRSLYADAISIFILPPSMEALEQRLNNRAQDSAEVIARRLAAAREEMRHVTEFDYVTINDRFEHALEDLRAIIRSQRLRREKQLIRYQDVVQKLL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB1_ARATH
Sequence: MREILHVQGGQCGNQIGSKFWEVICDEHGVDPTGRYNGDSADLQLERINVYYNEASGGRYVPRAVLMDLEPGTMDSIRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDAVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLSTPSFGDLNHLISATMSGVTCSLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYISLTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQILNVQNKNSSYFVEWIPNNVKSSVCDIPPTGIKMASTFVGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEDEYDEEEEQVYES
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS10_ALKMQ
Sequence: MSKANQKIRIRLKGYDHKAVDQSAEKIVATAKKSGAEVSGPIPLPTEKQIITILRAVHKYKDAREQFEMRTHKRLIDILSPTPKTVDLLMRLDLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GCSP_SHEON
Sequence: MTKQTLTQLEQHDLFLRRHIGPDSSQQQEMLNYVGAESLDDLTAQIVPESIRLSQELSIGDSCGEAEGIAYIRGLAKQNQVFKSYIGMGYYGTQVPNVILRNVLENPGWYTAYTPYQPEIAQGRLEAILNFQQVSMDLTGLDLASASLLDEATAAAEAMALAKRVSKAKKANIFFVADDVFPQTLDVVKTRAECFGFEVVVGPASEAVNHELFGALFQYSNRFGQITDFTDLFAELRAKNVIVTVAADIMSLVLLKSPGSMGADVVFGSAQRFGVPMGFGGPHAAFFVARDEHKRSMPGRIIGVSKDTRGNRALRMAMQTREQHIRREKANSNICTAQILLANMASFYAVFHGPQGLKTIASRINRFADILAAGLQAKGVSLVNNTWFDTISIKGLDVAAVNARALAAEMNLRFDADGIVGVSLDETTIRTDIDALFEVILGAGHGLDVAALDAQIVAQGSQSIPASLVREDAILSHPTFNRYQSETEMMRYIKRLESKDLALNYSMISLGSCTMKLNAAVEMIPVSWPEFANMHPFCPLDQAKGYTQLIEELSSWLVNVTGYDAVCIQPNSGAQGEYAGLLAIRKYHESRGEAHRNICLIPQSAHGTNPASAQLAGMQVVVTACDKQGNVDLEDLKAKAAEVAENLSCIMITYPSTHGVYEETVREICNIVHQHGGQVYLDGANMNAQVGLTSPGFIGADVSHLNLHKTFAIPHGGGGPGMGPIGVKAHLAPFVAGHVVVKPGRESDNNGAVSAAPYGSAGILPISWMYIKLLGSKGLKKSTQTALLNANYVMKKLSEHYPVLFRGRNDRVAHECIIDLRPIKEASGVTEMDIAKRLNDYGFHAPTMSFPVAGTLMIEPTESESKVELDRFIDAMVSIRAEIAKVEAGEWPADNNPLHNAPHTMADIMDSAFDSRPYSREVAVFPSAAVRTNKFWPTVNRIDDVYGDRNLFCACVPLSDYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: DERPC_MOUSE
Sequence: MKEPRIFPRERPTPWTRAPLPPRGRLDGGPVMNAGHPMGVNSDPFLMAAGSLGGNLAPFPRNAAPFQNPSGSLASNPAHFAAGARDPGMTSFPRGMNPTGTGAVSFPRPGGLLGPGPGPGLNPRTGALPGPGPMSNPRLGGLPGPGPMANPRAGGLLGASPDPRSGGPMVPGCGPNMRAGVLSSGTGPPNPRPVGLGPGPSPNLRSSFLGTNPAPRSGMFPGPGLGPNPRACGLGPGLGPNPRAGGLGPGPNLDNRAGGLLGTGSGLNLRMAGPQGLDLAPILRAAGLLGTNSVSFSQASGNMGTNPPTMTRVPGPIGPNTGPSSRGLGLPGPNPSPMSRAPGPMGPNSAHFSRPGGPMGVNAGVFPRGTGSGGLNPNAFSQSSGTLASNPGTFQRSAGLQGSNQAVFPRASGPLGPNPANFPRATGLQGPSPAAFPRSAGPLGPGQVAFPRSAAGHLGSSPAGPVGINPAPFARPTGTLGLNPASFPRMNGPVGKTLVPFPRVGSLPGSNPAAFPRPGGPMAAMYPNGMLPP
What is the function of this protein?
Potential tumor suppressor.
What are the official names of this protein?
Decreased expression in renal and prostate cancer protein.
What is the protein family that this protein belongs to?
Belongs to the DERPC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBK_SOLTU
Sequence: MLNTFSLIGICLNSTLYSSSFFFGKLPEAYAFLNPIVDIMPVIPLFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ATPA_PSEFS
Sequence: MQQLNPSEISEIIKGRIDKLDVTSQARNEGTVVSVSDGIVRIHGLADVMYGEMIEFPGGVYGMALNLEQDSVGAVVLGAYTSLAEGMSAKCTGRILEVPVGKELLGRVVDALGNPVDGKGPLGNTETDAVEKVAPGVIWRKSVDQPVQTGYKAVDAMIPVGRGQRELIIGDRQIGKTALAIDAIINQKNSGIFCVYVAIGQKQSTIANVVRKLEENGALANTIIVAASASESPALQFLAPYSGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVSEEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESAMFNSGIRPAVNAGVSVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDEATRKQLEHGQRVTELMKQKQYAPMSIADMALSLYAAERGFLTDVEIAKVGSFEQALIAYFNRDHAELMAKINVKGDFNDDIDAGMKAGIEKFKATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RR8_DRIGR
Sequence: MSKDTIADIITSIRNADMDKKGTVRIASTNITENIIKILLREGFIENVRKHRENNKYLLILTLRHRRNRKGTYRNILKCISRPGLRIYSNYKRIPRILGGIGIVILSTSRGIMTDREARLKGIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: THIC_HUMAN
Sequence: MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
What is the function of this protein?
Involved in the biosynthetic pathway of cholesterol.
What are the official names of this protein?
Acetyl-CoA acetyltransferase, cytosolic, Acetyl-CoA transferase-like protein, Cytosolic acetoacetyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: VE8E2_HPV42
Sequence: MKALSVIHSTTSTDAEIPSTGSTKLVQQVCTTNPLHTTTSIDNHHADCTDGTAYNVPIQTSPPRKRYRQCGQSPSQHLQHSNPSIPSIPSASVDPGLCGVRTNSENCNKRRNHCGSQATPVIHLQGDPNCLKCLRFRLKRNCSHLFTQVSSTWHLTENDCTRDTKTGIITIHYYDEAQRNLFLNTVKIPSGIKSCIGYMSMLQFI
What is the function of this protein?
Plays a role in limiting the replication of viral DNA in keratinocytes.  Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.
What are the official names of this protein?
Protein E8^E2C.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E8^E2C protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: HIS6_THET2
Sequence: MSLAKRIVPCLDVHAGRVVKGVNFVNLRDAGDPVEAARAYDEAGADELVFLDISATHEERAILLDVVARVAERVFIPLTVGGGVRSLEDARKLLLSGADKVSVNSAAVRRPELIRELADHFGAQAVVLAIDARWRGDFPEVYVAGGRVPTGLHAVEWAVKGVELGAGEILLTSMDRDGTKEGYDLRLTRMVAEAVGVPVIASGGAGRMEHFLEAFQAGAEAALAASVFHFGEIPIPELKRYLAEKGVHVRLD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_SACD2
Sequence: MAVQQNRKTRSRRGMRRSHDALTGKTLSVDSTTGEKHLRHHVTPDGFYKGRKVVDVADDE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.