PharMolix/UniProtQA huggingface dataset:
Protein: RK10_SPIOL
Sequence: MESTLFLSKPLPTTIKTTTHSLSSVYPNPFKPNNLTFPRTTHKHPTTTTITAAISRTKKEETVETVQKHLENCYLLAAINYKGFTVKQFQDLRKALPENTTLIVAKNTLVEKAVQDTQWAAIKPCMKGMNAWLFVHSEEIPIAIKPYRTFQKERKLEDNDFTGACFEGKFYGPGEVKRLETMPSKAEIFAKLLGSLKSPGSALVGTLQAPARDLVFLLKAYIKKLEDEQQQG
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
50S ribosomal protein L10, chloroplastic, CL10, Chloroplastic large ribosomal subunit protein uL10c.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BGA13_ARATH
Sequence: MKIHSSDHSWLLLAVLVILLSFSGALSSDDKEKKTKSVDKKKEVTYDGTSLIINGNRELLYSGSIHYPRSTPEMWPNIIKRAKQGGLNTIQTYVFWNVHEPEQGKFNFSGRADLVKFIKLIEKNGLYVTLRLGPFIQAEWTHGGLPYWLREVPGIFFRTDNEPFKEHTERYVKVVLDMMKEEKLFASQGGPIILGQIENEYSAVQRAYKEDGLNYIKWASKLVHSMDLGIPWVMCKQNDAPDPMINACNGRHCGDTFPGPNKDNKPSLWTENWTTQFRVFGDPPAQRSVEDIAYSVARFFSKNGTHVNYYMYHGGTNFGRTSAHYVTTRYYDDAPLDEFGLEREPKYGHLKHLHNALNLCKKALLWGQPRVEKPSNETEIRYYEQPGTKVCAAFLANNNTEAAEKIKFRGKEYLIPHRSISILPDCKTVVYNTGEIISHHTSRNFMKSKKANKNFDFKVFTESVPSKIKGDSFIPVELYGLTKDESDYGWYTTSFKIDDNDLSKKKGGKPNLRIASLGHALHVWLNGEYLGNGHGSHEEKSFVFQKPVTLKEGENHLTMLGVLTGFPDSGSYMEHRYTGPRSVSILGLGSGTLDLTEENKWGNKVGMEGERLGIHAEEGLKKVKWEKASGKEPGMTWYQTYFDAPESQSAAAIRMNGMGKGLIWVNGEGVGRYWMSFLSPLGQPTQIEYHIPRSFLKPKKNLLVIFEEEPNVKPELIDFVIVNRDTVCSYIGENYTPSVRHWTRKNDQVQAITDDVHLTANLKCSGTKKISAVEFASFGNPNGTCGNFTLGSCNAPVSKKVVEKYCLGKAECVIPVNKSTFEQDKKDSCPKVEKKLAVQVKCGRDKKN
What are the official names of this protein?
Beta-galactosidase 13, Lactase 13.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: LEPA_ECOSE
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVRCSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTLARNPAEKALPGFKKVKPQVYAGLFPVRSDDYEAFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPAVNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IFT88_HUMAN
Sequence: MMQNVHLAPETDEDDLYSGYNDYNPIYDIEELENDAAFQQAVRTSHGRRPPITAKISSTAVTRPIATGYGSKTSLASSIGRPMTGAIQDGVTRPMTAVRAAGFTKAALRGSAFDPLSQSRGPASPLEAKKKDSPEEKIKQLEKEVNELVEESCIANSCGDLKLALEKAKDAGRKERVLVRQREQVTTPENINLDLTYSVLFNLASQYSVNEMYAEALNTYQVIVKNKMFSNAGILKMNMGNIYLKQRNYSKAIKFYRMALDQVPSVNKQMRIKIMQNIGVTFIQAGQYSDAINSYEHIMSMAPNLKAGYNLTICYFAIGDREKMKKAFQKLITVPLEIDEDKYISPSDDPHTNLVTEAIKNDHLRQMERERKAMAEKYIMTSAKLIAPVIETSFAAGYDWCVEVVKASQYVELANDLEINKAVTYLRQKDYNQAVEILKVLEKKDSRVKSAAATNLSALYYMGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEALYNIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLYQIANIYELMENPSQAIEWLMQVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQYFERASLIQPTQVKWQLMVASCFRRSGNYQKALDTYKDTHRKFPENVECLRFLVRLCTDLGLKDAQEYARKLKRLEKMKEIREQRIKSGRDGSGGSRGKREGSASGDSGQNYSASSKGERLSARLRALPGTNEPYESSSNKEIDASYVDPLGPQIERPKTAAKKRIDEDDFADEELGDDLLPE
What is the function of this protein?
Positively regulates primary cilium biogenesis (PubMed:17604723).  Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
What are the official names of this protein?
Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, Tetratricopeptide repeat protein 10, TPR repeat protein 10.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cell projection, cilium, flagellum. Note=Colocalizes with ENTR1 and gamma- tubulin at the basal body of primary cilia. Colocalizes with ENTR1 and pericentrin at the centrosome.
Protein: Y7K7_BPP22
Sequence: MKIAIYKPGGSIMVWGVMAQMKVIDSSELPEYVKDGWLDHPSKLLPVEADDVKPRKGRKPKAVSDADKD
What are the official names of this protein?
Uncharacterized 7.7 kDa protein in gp5-gp4 intergenic region, ORF 109, ORF69.
Protein: TSAD_ECO5E
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_METMP
Sequence: MKKLNADDYIDILNDVLKDICPTDSEKEELKIFSDKIISKIKDISKYPVLDIIQVGSTARDANLKNDHDIDIFLRFEKETDRDMLKELGLKLGKDVINYFNGKSWIEYAEHPYVSGEIGKFNLDIVPCYDIENCEKIISAVDRTPLHNEFLLNAYENNDLSNDIRLLKKFLKGLGIYGSDLKTAGFSGYLCELLILKYRGFLNLLSAVQTWKPKHSIVLDEIYEMYDLKKDHDFLKFNDSLVVYDPVDLNRNVAAALNKENLCKFIFYSKMFLKKPSKEFFYGFYKKTTDLLNQRKRGYLITLEILRPENIVEDVIYPQMEKIQKSINKLVKEHDFEYLQYQNFADDNTCYLSWEFLIHELPDVKLRIGPPVYSEQGVLNFITHNEHYFVKECNVCAYKTRKYKNIQILFEDIVNGKLKNIITYPKYVCPENAKIRLGTFIERK
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
Protein: PUR7_STRE4
Sequence: MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEGKGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSKRFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAYLKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLGSLTQAYETVLERLRALDQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: ACP2_ARATH
Sequence: MASIAASASISLQARPRQLAIAASQVKSFSNGRRSSLSFNLRQLPTRLTVSCAAKPETVDKVCAVVRKQLSLKEADEITAATKFAALGADSLDTVEIVMGLEEEFGIEMAEEKAQSIATVEQAAALIEELLFEKAK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein 2, chloroplastic, ACP-2.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FABH_GEOKA
Sequence: MGAGIIGVGRYVPEKVLTNFDLEKMMDTSDEWIRTRTGIEERRIAADDIDTSDMAYFAAKRALQDAGMEAKDIDLILVATVTPDRPFPSVACMLQERLGAVNAAALDISAACAGFMYGMVTAAQFIDTGAYKYILVVGADKLSKITDWTDRNTAVLFGDGAGAVVMGPVSPGRGILSFELGADGTGGKHLYKDEYIVMNGREVFKFAVRQMGESSVRVLEKAGLTKDDVDFLIPHQANIRIVEAARQRLELPEEKISTTIRRYGNTSAASIPISLVEELEAGKIHDDDLIIMVGFGGGLTWGAIALRWGR
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUTA_STAAC
Sequence: MTNNKVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSNRDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAHEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFAPGIVQTPMMESIAVATAEEAGKPEAWGWEQFTSQIALGRVSQPEDVSNVVSFLAGKDSDYITGQTIIVDGGMRFR
What is the function of this protein?
Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.
What are the official names of this protein?
Diacetyl reductase [(S)-acetoin forming], Acetoin(diacetyl) reductase, AR, Meso-2,3-butanediol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ADE_ASPOR
Sequence: MCKSDLHDFLHGLPKCEHHVHLEGCLAPDLIFELAKRNNVSLPNEPAYESIEALSHRYGHFTSLDDFLRFYFIGMSVLHHESDFADLAWAYFQKAHADGVHHAEVFFDPQVHRDRGIPYETIVSGFVAGCQRAERELGLTTRLILCFVRHLPVDNAARVYQEALDQEHFDNEVVHGLGWSSTEVGPPKDMFRELYSSASAKGIRLTAHAGEEGDPSYISAALELGAQRIDHGIRLVEDPVLMEKVVRDRIMLTVCPISNLQLRCVESIAHVPIRKFLDAGVMFSINSDDPAYFGGYILDNYCAVQEAFQLTVDEWRVIAENSIKGSWIGEERKTELLKRIDDHVQRHVAAV
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL14_PROM2
Sequence: MIQQETYLTVADNSGAKRLQCIRVLGSNRRYAHVGDVIVATVKDALPNMGVKKSEVVKAVIVRTKATLRRNTGNSIRFDDNAAVLINEDKNPKGTRVFGPVARELRDKNYTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RSGA_SALPB
Sequence: MSKNKLSKGQQRRVNANHQRRLKTSAEKADYDDNLFGEPAEGIVISRFGMHADVESADGEVHRCNIRRTIRSLVTGDRVVWRPGKAAAEGVNVKGIVEAVHERTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVGCETLQVEPLIVLNKIDLLDDEGMDFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGVGKSSLLNALLGLQNEILTNDVSNVSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLWHLEPEQITQGFVEFHDYLGHCKYRDCKHDADPGCAIREAVENGAIAETRFENYHRILESMAQVKTRKNFSDTDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_STRSV
Sequence: MEINTHNAEILLSAANKSHYPQDDIPEIALAGRSNVGKSSFINTLLNRKNLARTSGKPGKTQLLNFFNIDDKLRFVDVPGYGYARVSKKEREKWGRMIEEYLTSRENLRAVVSLVDLRHDPSADDVQMYEFLKYYDIPVILVATKADKIPRGKWNKHESAIKKKLDFDKNDDFILFSSVTKDGLDAAWDAILSKI
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: HEMH_BURMS
Sequence: MSFDSVPRHALSMRFDLEPPSHASAAHRVAVLLVNLGTPDAPTPRAVRRYLAQFLSDPRVVEIPQLVWQVILCTLILPLRGRASAKKYAAVWLPEGSPLRVYTERQVESVKPLFAANGYRVIVDYAMRYGTPSIADVLAQLKRAGAERVLLLPMYPQYSSSTTATAFDAAFAALGRMRNQPEVRTVRHYADHPAYIHALAEQVRQYWAAHGRPAFDAGDKLVLSFHGVPKRTLDLGDPYHDQCQQTAALLMSALGLTTFECRVTFQSRFGKAEWLQPYTAPTLKELGAAGVRRADVFCPGFTADCLETIEEIGIEVRDEFVHGGGKEFHRIPCLNASPAWIAALGEIAAENLQGWPVRVAMAPEAVS
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_DICT6
Sequence: MEYFELILKTKKDLEEPIIAILEILGSKGTAIEDNFFDNSVLWDYVDEEFAERDYVLIRSYFDKDTDMEEIINRLKARIKENFEGLGDVEDVEYRVVKEEDWANEWKKYAKPIYVGRILILPSWEKVDTTEDKILVIMDPGMAFGSGSHPTTIMCIEMLQKYLKEGMDVLDVGTGSGILSIVAKKLGAGKVKGIDIDKKAVEVAKENAKRNNVELEFQQANLTIGIEDKYDIVVANLIAEIILKLNSEVKRVLKESGVYITSGIIGEKLDMVLKSFEENNIKILEIREKEGWFTVVGKNED
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLE2_CAEEL
Sequence: MTRNAPPGQESTDLAWLVTPAKDLVENFSIDVLKALAGYLEVIRQESEDTDNQVDAATTYRLFDFQRACRIIQGSCAVYGRKVDHVYELTISVVDLVENKGQDDGNTGSRRGAGRRKNFNLGSTNYDLADIDSLKQEALANFEKTVKEEKKSIDAVRMVENAEVIESQYERKSCLVAKPTQFMFKLNYGQLNRTDEQILNAKSRPDVIGKVKDFEIKKSKVKHDQQILYSHDCYRGNLDQFTLPGARWMPDNKELAANFGVADLEVELDLEQEHEKISAYGPFKDPLSGREVVPPPRWFIEQEAVRQNQEIQSRATSRAITIAAKTLRDSQGFGSQPTRLSQPFVERHRQSNHLNDFLSFVEGRVNKNRPSTHLTTGLVDMFVDNFGSVMQNDEPNTSRRPDENYAPMDFDDDFGGGGDDDDDDYIRNLSRRDEKRAPAPWDELDKNHIIWYTGDENLPVVSKPVKKITKFQPKPAEMLARKQRREEKINKSRRDEFMETHDYLQDYYYWRSAARINPIKDWKIESLRTAILAEKKRRIKEKTAKIREARIQNMQRKRTARVIPVEQFEPVTEDIPTSNRRTLGAEYDDVVDEDLAAEVELSMFGGGFDDDEEDVRPRGERPPMAPNNLEFDALQTDFDIPPAEYVPLRFEDIDDAELNSVINLPGNLLIDKALPLLKKFAENRTDREQMAYEMAKAYEDVDVAVSTLQEHVDKWHSRMEPILEEGETRKEYDVHAVGRAVIGQYDIEGGTKRLLDLVMDRPWYEISRYFLSCLFMCNVGNVMVSEDMELPLEERINSMKITLLKRDMHCEMFKEAGALDA
What is the function of this protein?
Regulatory subunit of the condensin II complex, a complex that seems to play a role in prophase chromosome condensation and in chromosome segregation in mitosis and in meiosis.
What are the official names of this protein?
Condensin-2 complex subunit kle-2, Kleisin, abnormal closure, protein 2.
What is the protein family that this protein belongs to?
Belongs to the CND2 H2 (condensin-2 subunit 2) family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=Localizes to the core of each sister chromatid in meiosis (PubMed:19119011).
Protein: PRCT_CARMA
Sequence: RYLPT
What is the function of this protein?
Stimulates cardiac output and hindgut motility, modulates visceral and skeletal muscle in many arthropods.  Also inhibits activities of the human peptidase neprilysin (NEP/MME) (PubMed:26056922).
What are the official names of this protein?
Proctolin.
What are the subcellular locations of this protein?
Secreted.
Protein: LYPA1_HUMAN
Sequence: MCGNNMSTPLPAIVPAARKATAAVIFLHGLGDTGHGWAEAFAGIRSSHIKYICPHAPVRPVTLNMNVAMPSWFDIIGLSPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFPQGPIGGANRDISILQCHGDCDPLVPLMFGSLTVEKLKTLVNPANVTFKTYEGMMHSSCQQEMMDVKQFIDKLLPPID
What is the function of this protein?
Acts as a acyl-protein thioesterase (PubMed:19439193, PubMed:20418879).  Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (PubMed:20418879).  Has depalmitoylating activity toward KCNMA1 (PubMed:22399288).  Could also depalmitoylate ADRB2 (PubMed:27481942).  Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC) (PubMed:19439193).  Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS) (By similarity).  Has much higher thioesterase activity than lysophospholipase activity (PubMed:19439193).  Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA (PubMed:21393252).
What are the official names of this protein?
Acyl-protein thioesterase 1, APT-1, hAPT1, Lysophospholipase 1, Lysophospholipase I, LPL-I, LysoPLA I, Palmitoyl-protein hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Nucleus membrane. Endoplasmic reticulum. Note=Shows predominantly a cytoplasmic localization with a weak expression in the cell membrane, nuclear membrane and endoplasmic reticulum.
Protein: NADA_STRCO
Sequence: MTTAQTQELDVQPTPLALLLLGREADPRSERGVECPGDLPSPSDPDLVARARAAKEKLGDKVFVLGHHYQRDEVIQFADVTGDSFKLARDAAARPEAEYIVFCGVHFMAESADILTSNDQKVVLPDLAAGCSMADMATAEQVAECWDVLTEAGIAEQVVPVSYMNSSADIKAFTGKHGGTICTSSNAERALNWAFEQGEKVLFLPDQHLGRNTAVRDLGMSLEDCVVYNPHRPNGGLTAKELRDANMILWRGHCSVHGRFSLDSVNDVRERIPGVNVLVHPECKHEVVAAADYVGSTEYIIKALEAAPAGSKWAIGTELNLVRRLANRFAAEDKEIVFLDKTVCFCSTMNRIDLPHLVWTLESLAEGTLVNRIEVDQETEAFAKLALERMLALP
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_BIFAA
Sequence: MTGENTGDNPRRVLLKLSGEAFGGGKVGIDTTVVRRIAEEIVPAVKQGVQVAIVVGGGNFFRGAELQQAGIDRSRGDYMGMLGTVMNCLALQDFLEQEGQATRVQTAITMGQVAEPYIPLKAIRHLEKGRVVIFGAGAGMPYFSTDTVSIQRSLEIHCDEVLMGKNGVDGVYTADPRKDENAKRFATLSYNRALVDNLAVMDAAALSMARDNKQRIRVFGLEGAGNVTQALLGEEIGTMVSTAESTLAE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETG_CUSGR
Sequence: MIEAFLLGIILGLIPITLIGLFVTAYLQYRRGDQLDF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: ERT12_YARLI
Sequence: MEKPVVISQRTGKPKRRKAHRACIHCQRTHLTCDNNRPCERCVARGFADTCVDGVRKKLKYLDDKEDNKPSKGLSPAPGVNVQPKLSPATRSARSSSAGFPDTKGNMQQQHMGNMPVPNTPQNGHPNLGTPGMAHTNLQGPQRQGAQQPQGGQSSTPSQLPADYLIHQQLLATEINQLGDLGRTGEGDFSSDWFSDLQLSGHSFQSVATNMEYSILSNMVYSSGQPNSAVSNSLLLGNNSQSPNTHSPHNQDQPTPQAATPSAKIKQLIESNGLSAKDLNQYPLAGEFVNDTFLTVPEIVAFNETRRNVKDSELTTDEKLRPLSFAVAAGQPQNTNGNGNGSEAPDSPSKSIFSSGALEAVYSNLPDYTDPIQVYTNITKPFSYTPGYHGLISYLKGRFNKQQLVQMTKYMAEYRPSFIACTNSLKEEDLVFMEQCFQRALLEYQKFISFSGTPTLVWRRTGQLAAVGKEFCQLSGWSEQRLIGQQTFIVELLDDNSVLEYFELFSRIAFGDSRGATMADCTLLTPTGAKIKTSSIWTLKRDVFGNPMMIVGNFLPILS
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis ERT1-2.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XERC_RICCN
Sequence: MLDTSIQALINKWQKYLALQRNYSNHTVISYNNDLKHFLEFMNYYNSELVTINHIKTADIRLIRSWLAKRNCDNFTASSISRGLSAVKNFYRFLEKTTQLNSHIIFSIKSPKKTKLLPKALSEDDVVISLEHIEEYGNVKWVELRNKALLVLIYASGLRISEALSITKLHLQNLEFIRIIGKGSKERIIPWLPIAKNLITQYLEILPYKLGDNEPIFRGKQGKKLQPPVFNRELIKLKHFYGLPQHLTAHSFRHSFASHLLEHGADLRSLQELLGHKSLSTTQNYTKTSIKHLEAVYTTAYPIKK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_BRUMB
Sequence: MQRITITIDDDLMAALDRMIEIKGYQNRSEALRDLARTGLQQASLEEGQMEACVGVLSYTYDHSARDLSKKLTNTHHDHHNISVASMHVHLDHDRCLEVSILKSKTDDVRHFADHVKAERHVTHGTLAVLPL
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.