PharMolix/UniProtQA huggingface dataset:
Protein: TRKA_ECO57
Sequence: MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSPDYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKAYYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQNTIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERLFQPSPFFL
What is the function of this protein?
Part of the constitutive potassium transport systems TrkG and TrkH.  May regulate the transport activity of TrkG and TrkH systems.  Binds to NAD(+) and NADH (By similarity).
What are the official names of this protein?
Trk system potassium uptake protein TrkA, K(+)-uptake protein TrkA.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripherally bound to the inner side of the inner membrane via the TrkG and TrkH proteins.
Protein: MXRA8_BOVIN
Sequence: MELRAWVLLWRLVLLQSSAVLLSSGPSGPATSDRSVVSESTVSWAAGARAVLRCQSPRMVWTQDRLHDRQRVVHWDLSGSKAGGPARRLVDMYSTGEQRVGEQRLGEQRVGEQRVYEPRDRGRLLLPPSAFHDGNFSLFIRAVEETDEGLYTCNLHHHYCHLYESLAVSLEVTDDPRAAGAHWDGEKEVLAVERGAPALLTCVNRAHVWTDRHLEEAQQVVHWDRQPPGVPHDRADRLLDLYASGERRAYGPPFLRDRVAVEADAFARGDFSLLIDPVEPADEGTYSCHLHHHYCGLHERRVFHLRVTEPAARPPPPPRDSPGNGSSHSGAPGPGARDPTLTRGRSVINVIVPEGRAHFFQQLGYVLATLLLFILLLITVVLATRQRRRGGYEYSNKKSKSKGKDINMAEFAVASGDQSLYRSEDIRLDYKNNILKERAEVAHSLPPAKNIDLDKEFRKEYCK
What is the function of this protein?
Transmembrane protein which can modulate activity of various signaling pathways, probably via binding to integrin ITGAV:ITGB3.  Mediates heterophilic cell-cell interactions in vitro.  Inhibits osteoclastogenesis downstream of TNFSF11/RANKL and CSF1, where it may function by attenuating signaling via integrin ITGB3 and MAP kinase p38.  Plays a role in cartilage formation where it promotes proliferation and maturation of growth plate chondrocytes.  Stimulates formation of primary cilia in chondrocytes.  Enhances expression of genes involved in the hedgehog signaling pathway in chondrocytes, including the hedgehog signaling molecule IHH; may also promote signaling via the PTHLH/PTHrP pathway.  Plays a role in angiogenesis where it suppresses migration of endothelial cells and also promotes their apoptosis.  Inhibits VEGF-induced activation of AKT and p38 MAP kinase in endothelial cells.  Also inhibits VTN (vitronectin)-mediated integrin ITGAV:ITGB3 signaling and activation of PTK2/FAK.  May play a role in the maturation and maintenance of the blood-brain barrier.
What are the official names of this protein?
Matrix remodeling-associated protein 8, Limitrin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Cytoplasm. Cell projection, cilium membrane. Nucleus. Note=Primarily localizes to the cell membrane. Detected in the cilium of primary chondrocytes. Highly expressed at areas of cell-cell contact and may localize to tight junctions. Also found in the nucleus where it is detected in the soluble (as opposed to chromatin-bound) fraction.
Protein: KLHL3_DANRE
Sequence: MVLWGFFLRFRFFLTCGRNCIQKTLDSQDDAKDPGLHTFSHTHMRKAFLLMNDLRSHSRKMLCDVLLVAGEVEIPAHRVVLASCSPYFCAMFTGDMSESKANHVEIRDVDGQTLLKLVDYIYSAEIEVSEENVQVLLPAASLLQLMDVRQVCCDFLQTQLHPTNCLGIRAFADLHACTVLLSQAHAYAAEQHFTDVMVGEEFMALSLQQVCSLISSDKLTVSTEEKVFEAMVAWIKHDKEARLEHMPKLMEHVRLPLLSRDYLVQIVEEEPLIKNNNTCKDFLIEAMKYHLLPADQRHLIKTDRTRPRTPISLPKVMMVVGGQAPKAIRSVECYDFQEDRWYQVADLPSRRCRAGVVYMAGKVYAVGGFNGSLRVRTVDVYDGLKDQWSSIPSMQERRSTLGAAVLGDLLYAVGGFDGSTGLSSVEAYNPKANEWMFVAPMNTRRSSVGVGVVDGKLYAVGGYDGASRQCLSTVEEFNPVSNKWCYVSDMSTRRSGAGVGVLSGQLYAAGGHDGPLVRKSVEVYDPTTNTWRQVCDMNMCRRNAGVCAINGLLYVIGGDDGSCNLSSVEYYDPAADKWSLIPTNMSNGRSYAGVSVIDKPL
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron.
What are the official names of this protein?
Kelch-like protein 3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytosol.
Protein: FTSZ_STRCO
Sequence: MAAPQNYLAVIKVIGVGGGGVNAINRMIEVGLKGVEFIAINTDAQALLMSDADVKLDVGRELTRGLGAGANPAVGRKAAEDHREEIEEVLKGADMVFVTAGEGGGTGTGGAPVVANIARSLGALTIGVVTRPFTFEGRRRANQAEDGIAELREEVDTLIVIPNDRLLSISDRQVSVLDAFKSADQVLLSGVQGITDLITTPGLINLDFADVKSVMSEAGSALMGIGSARGDDRAVAAAEMAISSPLLEASIDGARGVLLSISGGSDLGLFEINEAAQLVSEAAHPEANIIFGAVIDDALGDEVRVTVIAAGFDGGQPPSKRDNVLGSSSAKREEPTPARPSESRPSFGSLGSVKPKEEPEPAPVPEPVADLPVSPPPVPPSRTYSDSAAEELDVPDFLK
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: NAGB_LACPL
Sequence: MKVIVVKDQAAGGKEGFKVFKNALDNGAKVFGLATGSTPVTTYKEIVNSDLDFSDCTSVNLDEYVGIAPDNDQSYKYFMQTHLFNDKPFKESFLPNGLASDPEAEVKRYDKVIDEHPIDLQILGIGRNGHIGFNEPGTPRDITTHVVDLTESTIEANARFFASENDVPKQAFSMGLASIMKSKHLLLEAFGENKADAVKGMIEGPDTPELPASILQNHPDVTVIIDEAAASKLSKKY
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RL15_HALSA
Sequence: MTDKKRRQRGSRTHGGGTHKNRRGAGNRGGRGRAGRKKHEQHNYEDVGKSGFKRPEKTDRDVAVLSVQELDEDIPVLSESGVAEETEFGYRVDARDVVDDGWDADVVKVLGGGQLYEQLEVTADAFSDAAVELIEGEGGDAVVSERASEDDEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15, HL16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: XAC1_XYLAI
Sequence: GFVALLKKLPLILKHLH
What is the function of this protein?
Antimicrobial and mast cell degranulating peptide which probably acts by forming pores in membranes (PubMed:28546807, PubMed:28855917).  Active against both Gram-negative and Gram-positive bacterial strains as well as against yeasts (PubMed:28546807, PubMed:28855917).  Has leishmanicidal activity (IC(50)=25uM) (PubMed:28855917).  Has little hemolytic activity (PubMed:28546807, PubMed:28855917).  In the context of inflammation and cancer tests, is weakly cytotoxic to normal cells, induces calcium signaling but does not impact cAMP production (PubMed:36548715).  In addition, prevents LPS-induced nitric oxid (NO) synthesis but does not affect the IP3 signaling and pro-inflammatory activation of endothelial cells (PubMed:36548715).  Does not show significant antiproliferative activity on the breast cancer cell line MDA-MB-231 (PubMed:36548715).
What are the official names of this protein?
Antimicrobial peptide Xac-1, Xac1, Xylopin.
What is the protein family that this protein belongs to?
Belongs to the xylopin-like family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Assumes an amphipathic alpha- helical conformation in a lipid environment.
Protein: RISB_SULNB
Sequence: MKIVEGNLSVDKSKKVAIINARFNHFITDRLVEGAKDAYARHGGNPEELDLILVPGAFEIPFALDKALASGKYDAVCCLGAVIRGATPHFDYVSAEATKGVANVTLKYGKPATFGVLTVDSIEQAIERAGTKAGNKGAEAMAGLIELINLYGSLEK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RUVB_ACIBY
Sequence: MQDRLISGTEKPEDHFDRAIRPTSLADYIGQPVVREQMEIFIGAARGRGEALDHTLIFGPPGLGKTTLANIIAREMGGNLKSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVAATTRAGLLTSPLRDRFGIVQRLEFYSVEDLTHIVSRSANLMDVPITVEGAEEVARRSRGTPRIANRLLRRVRDYAQVKGTGEVNHEMAQRALDMLNVDKAGLDTLDRRYLSMLLERFDGGPAGVEALAAAMAEDSGTLEDVIEPYLIQQGYVMRTARGRIATNQSYLQFGMTPPEPKN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: XERC_BACP2
Sequence: MTNKQRLVHLFIEYLQIEKNYSALTISGYTEAIEEFVRFMNVQGIDGFEEVSYQDTRIYLTEAYEKGLTRRTISKKVSALRSFYKFLLREQLVKENPFLLVSLPKQDKRIPSFLYEEELKELFTVSDVSTPLGQRNQAILELLYATGMRVSELCSLKESDLDLSMDTVLVHGKGSKQRYVPFGSYAHEALITYLEDGRLKLKAKGKDRADAYVFLNQRGAPLTDRGVRFILTELMKKASGTLHIHPHMLRHTFATHLLNEGADLRSVQELLGHSNLSSTQVYTHVSKDSLRKTYMSHHPRAFKRS
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSOP_WHEAT
Sequence: MADEAKAKGNAAFSAGRFEEAAGHFSDAIALAPANHVLYSNRSAALASIHRYSDALADAEKTVELKPDWAKGYSRLGAAHLGLGDAASAAAAYEKGLALDPSNEGLKAGLADAKKAAAAPPRRAPSGGADAIGQMFQGPELWTKIASDPATRAYLDQPDFMQMLREVQRNPSSLNTYLSDPRMMQVLSLMLNIKIQTPQDSDFSQSSSPSQPPPQQQKQQPETKAREMEPEPQPEPMEVSDEEKERKERKAAALKEKEAGNASYKKKDFETAIQHYTKALELDDEDISYLTNRAAVYIEMGKYDECIEDCDKAVERGRELRADFKMVARALTRKGTALAKLAKNSKDYDIAIETFQKALTEHRNPDTLKRLNEAEKAKKDLEQQEYYDPKLADEEREKGNEMFKQQKYPEAIKHYNEAIRRNPKDARVYSNRAACYTKLGAMPEGLKDAEKCIELDPTFTKGYTRKGAVQFFMKEYEKAMETYQAGLKYDPNNQELLDGIRRCVEQINKANRGDISQEDLQEKQSKAMQDPEIQNILTDPIMRQVLMDFQENPRAAQDHLKDPGVAQKIQKLINAGIVQTR
What is the function of this protein?
Mediates the association of the molecular chaperones HSP70 and HSP90 (By similarity).  Mediates nuclear encoded chloroplast preproteins binding to HSP90 prior to chloroplastic sorting.
What are the official names of this protein?
Hsp70-Hsp90 organizing protein, TaHop.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MQO_MYCGI
Sequence: MSEAEKTDVLLVGAGIMSATLCALLRLLEPNWSMTLVERLDGAAAESSDPWNNAGTGHSALCELNYTPARPDGSIDIAKAVNVNEQFQVSRQFWTYAVENGVLPDVRSFLNPIPHVSFVTGADNVQYLRKRYEALVGNPLFGTMEFIDDAGEFARRLPLMAEGRDLREPVGLNWTQDGTDVDFGALSRQLLGFGAQQGMDTLFGHDVTNLSQNSDSTWTVKVVNRRTGRKRTFNAKFVFVGAGGGALPLLQKAGIKEAKGFGGFPVGGQWLRTGNPELTAKHQAKVYGLPPLGAPPMSVPHLDTRVINDKSWLLFGPFAGWSPKFLKQGKVTDLPFSVKPDNLVSMLGVGLTEMGLLKYLIGQLLLSEAARVENLREFAPSAKDSDWELDIAGQRVQVIRKAKGKGGVLEFGTTVLSAADGSIAGLLGASPGASTAVPAMFDVMKRCFADRYPSWEPKLKEMVPSLGVTLSDEPKLFEEVWARGTKVLKLDKPAGAIPATTDGQSTAGTEHTPTAATV
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: Y244_STRZT
Sequence: MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYVLLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE
What are the official names of this protein?
UPF0473 protein SPT_0244.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: APAH_ECOLC
Sequence: MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGEAAAS
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: RMLA_NEIGO
Sequence: MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILVITAPEDNAAFQRLLGDGSDFGIRLQYAVQPSPDGLAQAFIIGEEFIGNGNVCLILGDNIFYGQSFTQTLKQAAAKTHGATVFGYRVKDPERFGVVEFDENFNALSIEEKPQQPKSDWAVTGLYFHDNRAVEFAKQLKPSARGELEISDLNRMYLEDGSLSVQILGRGFAWLDTGTQESLHEAASFVQTVQNIQNLHIACLEEIAWRNGWLTKKDVETRAKHLEKTAYGQYLLHLIGK
What is the function of this protein?
Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.
What are the official names of this protein?
Glucose-1-phosphate thymidylyltransferase, dTDP-glucose pyrophosphorylase, dTDP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the glucose-1-phosphate thymidylyltransferase family.
Protein: PSK2_ORYSJ
Sequence: MSTTRGVSSSSAAAALALLLLFALCFFSFHFAAAARAVPRDEHQENGGVKAVAAVAADQLVLQLEGDTGNGDEVSELMGAAEEEAAACEEGKNNDECVQRRLLSDAHLDYIYTQHKNKP
What is the function of this protein?
Promotes plant cell differentiation, organogenesis and somatic embryogenesis as well as cell proliferation.
What are the official names of this protein?
Phytosulfokines 2.
What is the protein family that this protein belongs to?
Belongs to the phytosulfokine family.
What are the subcellular locations of this protein?
Secreted.
Protein: TUSA_PSEPG
Sequence: MTDFTPDAVLDATGLNCPEPVMMLHQHVRNLAAGGLLKVIATDPSTRRDIPKFCNFLGHELLQQQEDAGTFLYWIRKKAD
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_ACIAD
Sequence: MAKRDYYEVLGVSKTASDDEIKKAYRKLAMKYHPDRNPDNAEAEDKFKEASEAYEVLSDSEKRSMYDRMGHNAFEGGGGGGFGGFSAEDIFSQFGDIFGGAFGGGGRQQQRQRRGSDLRYVMELSLEEAVRGVKKTITFTAPAPCEVCDGKGSKNPNDVETCRTCHGTGQVRMQQGFFSVQQTCGTCRGQGKIIKNPCQSCHGSGVADRQQTLEVTIPAGVDNGDRVRLSGKGEAVRDGQAGDLYVEVVVREHEIFQRDGADLYMDVPVSIADAALGKEIEIPTLEGRVSLKIPEGTQTGKLFRLRGKGVRPVRSSMVGDLLCRVVVETPVNLTSRQRELFKELQATLDGDEHSSSPKKKSFFDRLFD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP2_RHIEC
Sequence: MTSTHADKTGDVASRTGFVGLVVGAIGVVYGDIGTSPLYAFREALRPFTADGVHEFEVIGLISLMIWTLTIIVTFKYVLFLLRADNDGEGGTLSLLALLMKKMGRNVPVLFFAGLIGSALFIGDAMITPALSVMSALEGLKLITPAFAEYVPPLSAAIMIVLFAAQSRGTAAVSMFFGPITVLWFFAMAAGGVIHIGDDWRILAAINPINALSFLAHAGTVGLIVLGAVFLTVTGAEALYADLGHFGRRPIQMAWFVLVFPALLLNYLGQGALVLSQPAASADPFFLMYPDWALLPVVLLATLATIIASQAVITGAFSLARQAVHLGFLPRLRIKFTSETNTGQIYVPSVNLLLLTGVLMLIFSFGDSESLATAYGISVTGAMVITTMLAFQFLRAVWGYSFMLASAALLPLFVIEVVFLAANLLKIQDGGWVPVALALAIMTLMWTWTRGQTYLKKLRANNEIPLDSFIRSIERKSDHSPVTVPGTAVFLTSVPDRTPNVLLHNLKHNHVLHEQNVILTVWTEDEPYVPDNRRIKISQLSPRFVRLDINFGFMDDPDVTRALALCREGGFKFEIMKTSFYLGRRNLVRTPNTGLPGWQERIFMALEGFAIDPSDYFNLPSNRVVELGEQVAI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NP_BPB03
Sequence: MRKMMQREVTYTTAQLARMKMEDGQVTAEVLEPVTLIGNLSVEQAQREINKRPEFKENPAQVVGVEPNTQLYELPLDVFLEHATVKERPAAKEEVAEVQA
What is the function of this protein?
Histone-like nucleoprotein that binds to the viral dsDNA and responsible for wrapping and compacting the viral DNA about 4-fold.  Forms a nucleoprotein complex in which the DNA adopts a right-handed toroidal conformation winding around a protein core.  Binds ito most, if not all, the viral genome, although with different affinity, the highest one corresponding to the genome ends.  The formation of the nucleoprotein complex at the genome ends, activates the initiation of viral DNA replication.  The binding of p6 would recruit the complex formed by the TP and the DNA polymerase to the origin.  Protein p6 also represses early transcription from promoter C2, and, together with protein p4, represses transcription from promoters A2b and A2c and activates late transcription from promoter A3.  Protein p6 is therefore involved in the early to late transcription switch.  The formation of the nucleoprotein complex at the right end of the phage genome where the early promoter C2 is located affects local topology, which may contribute to the promoter repression.
What are the official names of this protein?
Histone-like protein p6, Double-stranded DNA-binding protein, Double-stranded DNA-binding protein p6, Gene product 6, gp6, Histone-like binding protein, Nucleoid-associated protein p6, Protein p6.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus histone-like protein p6 family.
Protein: RL9_YERPS
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNVEFFEARRAELEAKLADVLAAAEARATKINELVSVTISSKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTAGEHEVHFQVHSDVFAKLNVVVVPEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: AROA_ECOLI
Sequence: MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SACD2
Sequence: MSRVANNPVQLPSGVQVDLKGSDLSVKGSKGAMSLSVHSSVAVVQEDNVLTFAAKDGAKSSKAMAGTVRSLVNNMVTGVSVGFEKKLQLVGVGYRTKVTGNVLNLTLGFSHPVDYVLPEGVTAETPTQTEIVLKCSDKQLLGQVAAEIRAFRPPEPYKGKGVRYADENVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SYM_ECO24
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNA_ECO5E
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPAGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNAHHCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.