PharMolix/UniProtQA huggingface dataset:
Protein: KDPB2_STAAN
Sequence: MHHVNKYFNQTMVIEALKMSFYKLNPKQLIKNPIMFVVEVGMVLTLILICFPDIFGTSYLSRGYLITIFIILLITILFANFSEAFAEGRGKAQADSLRQAQSNLTARLIEENGAYRIVNATELKAGQNIRVENGETIPADGVVINGLATVDESAITGESAPVIKESGGDFDGVIGGTLVTSDWLEIRVESEAGTSFLDKMIALVEGAERNKTPNEIALFTLLTTLTIIFLVVIVTLYPIASYLHLILPIAMLIALTVCLIPTTIGGLLSAIGIAGMDRVTQFNVLAKSGRAVEVCGDVDVMILDKTGTITYGNRIASEFLPVNQQMLEKLIVAAYMSSIYDDTPEGKSIVRLAKQMYINELPKDIDGTYKPFTAETRMSGIITNEISVFKGAPNSMINLVKQQQGNIPLNIESLCMDVSSKGGTPLIVIENNVMLGVIYLKDVIKDGLVERFTELRKMGIETVMCTGDNALTAATIAKEAGVDRFVAECKPEDKIKVIKDEQAKGHIVAMTGDGTNDAPALAQANIGLAMNSGTISAKEAANLIDLDSNPTKLIEVVKIGKQLLMTRGALTTFSLANDVAKYFAILPALMMSTIPEMTSLNIMHLSSPKSAIISALIFNALIIVALIPIAMKGVKVKGYSIDRIFINNMLIYGLGGLIVPFLGIKLIDMIVQFFV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit 2, ATP phosphohydrolase [potassium-transporting] B chain 2, Potassium-binding and translocating subunit B 2, Potassium-translocating ATPase B chain 2.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYC_RHILO
Sequence: MSDASQGLRLYNTLTRAKTDFVPIDALNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHLYGQAHVTYVRNITDVDDKINARALRDFGSEISAGKLSLNEAIRRVTEKTADQFHRDVATLGCLEPTVEPRATEFVEPRADGKADMITLIQSLIKRGHAYAAAGEVLFDTASMPDYGQLSKRNLDEQQAGARVAVDAHKKNPGDFVLWKLSSPEEPGWQSPWGRGRPGWHIECSAMSAAYLGEVFDIHGGGLDLIFPHHENEIAQSRCAHGTSVMANVWMHNGFLQVEGQKMSKSLGNFYSIHELLETETFGGRSWPGEVLRLAMLMTHYREPIDFSVRKLEEAENTLRKWKRAADLAPAAGQLPVEVIDALSDDLATYAAFQVLTQLAGEAADGNEAAAALKASLLFLGFDVASADIDEDGVAKAIANRLALIAAKNWTEADRIRDELLAQGVQLKDGKDPVTGERITTWEVKR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_PARPJ
Sequence: MQFDVVTLFPDMFRALTDWGITSRAAKQERYALRTWNPRDFTTDNYRTIDDRPYGGGPGMVMLAKPLEDAIGAAKAAQAEQGIGASRVVMMSPQGATLNHDRVMQFAAEPGLILLCGRYEAIDQRLLDRVVDEEVSLGDFVLSGGELPAMALMDAVVRQLPGVLNDSQSAVQDSFVDVLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEAWRRREALRNTLKKRPDLIVKARRNKMLSRADEAWLASLAKEESKA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPTC1_MOUSE
Sequence: MAALDSDSDEDLISYGTGLEPLDEGERPKKPIPLQDQTVRDEKGRYKRFHGAFSGGFSAGYFNTVGSKEGWTPSTFVSSRQNRADKSALGPEDFMDEEDLSEFGIAPKAIVTTDDFASKTKDRIREKARQLAAAAAPIPGATLLDDLITPAKLSVGFELLRKMGWKEGQGVGPRVKRKARRQKPDPGVKIYGCALPPGGSEESEDEDDDYLPDNVTFAPKDVMPVDFTPKDNVHGLAYKGLDPHQALFGMPGEHLNLFGGASEGTSHLLGDVGLSKGRKLGISGQAFGVGALEEEDDDIYATETLSKYDTVLKDEEPGDGLYGWTAPKQYKNQKEPERDLRYVGKILEGFSLASKPLSSKKIYPPPQLPRDYRPVHYFRPVVAATAENAHVLQVLSESSGKAGQDVGTHSRHQLNASKRGELLGEMPIQGSATSVLEFLSQKDKERIKEVKQATDLKAAQAKARSLAQSASSSRAQASTPDLGHSSWHLALGGGTVTTRANNFKPFAKDPEKQRRYEEFLVHMKKGQKDALERCLDPSMTEWERSREREEFARAAQLYVSSNSTLSSRFTHAKEEEDSDQVEVPRDQENDVSDKQSAVKMKMFGKLTRDTFEWHPDKLLCKRFNVPDPYPGSTLVGLPRVKRDKYSVFNFLTLPEPAPLPTAPVPSEKAPQQRGSDKSRKPSRWDTSKQEKKEDSISEFLSQARSKVGPPKQESSALGSKEEQAPEPRPDTTVDKAVDAQTDGEGSRPSMDLFKAIFASSSDEKSSSSEEEQDDSEDSQEHTEEASLKGSQEAAAGETSVVLAAEPEPCEPATPFPIQKAQIDEREEFGPRLPPVFCPNSRQKLEIPQKEKPKKSKERHKSKKEHRRKREKKKKHKKHKHKSKQKNKKSEKNSSSESTDSSDSGSDDGGPAELSPQELLRRLKCLPLRRQ
What are the official names of this protein?
G patch domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the GPATCH1 family.
Protein: Y2134_ARCFU
Sequence: MLASVLILGAIAVGSAIPTIAELKVDRSLCRKSPMEEFYVFENGEWVKKEELADWWLCIDVDSIERSDYYSAAKKAIELQKLGRDSPYYGGEWIGC
What are the official names of this protein?
Uncharacterized protein AF_2134.
Protein: DIOX1_RUTGR
Sequence: MAPTKDFSTTTTNGAESWDDVADFVTKKGHGVKGLSERGIKTLPKPFHQPLEERFSEKKILERASIPLIDMSQWDSPEVVKSICDAAENWGFFQIVNHGVPLETLERVKEATHRFFGLPAEEKNNYSKENSPINNVRFGSSFVPHVEKALEWKDFLSMFYVSEEETNTYWPPICRDEMLEYMRSSEVLIQRLMEVLVVKGLKVKQIDEIREPMLVGSRRINLNYYPKCPNPELTLGVGRHSDISTFTILLQDQIGGLHVRKLDDTGNTWVHVTPIAGSLIINIGDALQIMSNGRYKSIEHMVVANGTQDRISVPLFVNPKPQAILCPFPEVLANGEKPVYKPVFCSDYSRHFYTKPHDGKKTVDVAMIN
What is the function of this protein?
2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD) involved in scopoletin and umbelliferone biosynthesis (By similarity).  Converts feruloyl CoA into 6'-hydroxyferuloyl CoA, and p-coumaroyl CoA into 2,4-dihydroxycinnamoyl-CoA (By similarity).
What are the official names of this protein?
Bi-functional coumaroyl CoA and feruloyl CoA ortho-hydroxylase Diox1, 2-oxoglutarate-dependent dioxygenase 1.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: REX_CLOBJ
Sequence: MDKKKNISMAVIRRLPKYHRYLYELLKNDVDRISSKELSEKIGFTASQIRQDLNCFGDFGQQGYGYNVSELHHQISNILGLNNPYNIIIIGAGNIGQALANYTRFSKLGFNVKAMFDTNPKLIGLKIREIEILDIDYLSSYLEKNNIDIGIICVPHDNAQKVANILVKNDIKGIWNFAPIDLSVPEDVVVENVHLSDSLLTLTCLINKTE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_BORA1
Sequence: MTQNATSETLGFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDACDKLRFEAIDQPELLAGDSELAIRVSYDKAARTITIADNGIGLSREEAIANLGTIARSGTREFFSQLTGDKQKDAQLIGQFGVGFYSSFIVADRVSVLSRRAGSDEAIRWESDGQGEFSIASAEKATRGTDVVLHLRADEDEFLNGWKLREVLRRYSDHISLPILMRKEEWDADKDEQVTRDEWETVNQANALWTRSKSEISDEQYREFYKTVSHGFDEPLAWTHNRVEGRSEYTQLLYVPRQAPFDLWDRDARRGVKLYVKRVFIMDDAEQLLPAYLRFVRGVIDSADLPLNVSREILQESRDVRAIREGSAKRILSLLEDLAENRKDDYAVFWGEFGQVLKEGVGEDPSNQERIAKLLRFASTHAGDASQTTSLQDYLGRLKEGQDKIYYVTADSYSAASNSPHLEIFRKKGIEVLLLWDRVDEWMLSHLREFEGKSLVSVAKGGLDLADLADEEEKKKQTEVAESFKPLIERLQTALGEQVKEVRVTLRLVDSPACVVVGQNDLSPHLLRMLKAAGQEVPEVKPVLEINPEHALIARIRDVSDADFGAWAQLLLDQALLAEGAQIADPAAFVKRLNALLLKV
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_AERS4
Sequence: MNQSLLSEFGDPLARVEAALAALRAGRGVLVADDEDRENEGDLIFAAQTMTNEQMAMMIRECSGIVCLCLTDERVRQLALPMMVEANSSHYQTAFTVTIEAAQGVTTGVSAADRITTIRAAIADGAKPSDLHRPGHVFPLRARTGGVLTRRGHTEATVDLMQLAGLKPFGVLCELTKEDGSMARLPDLVAFGRLHQMPVLTIEDLVQYRQLLSERSA
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: NUOB_HELPY
Sequence: MQQAPVVLSTLDKLLNWGRSNSLWPLTYGLACCAIEMMATGGSRFDFDRFGTIFRASPRQSDVMIIAGTLTKKHAEFMRRLYDQMPEPKWVISMGSCANTGGMFNTYATVQGADRVVPVDIYLPGCAPRPETLQYALMVLQDKIRRSKAIKQDAPKRLV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MTNN_KLEP3
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTITIGGSEIYTGQLHGVDVALLKSGIGKVAAATGATLLLERCQPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLVAAAEDCIKALDLNAVRGLIVSGDAFINGSVALAKIRHNFPQAIAVEMEATAIAHVCHNFKVPFVVVRAISDVADQQSHLSFEEFLAVAARQSTLMVENLVQNLARG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: SHD_HUMAN
Sequence: MAKWLRDYLSFGGRRPPPQPPTPDYTESDILRAYRAQKNLDFEDPYEDAESRLEPDPAGPGDSKNPGDAKYGSPKHRLIKVEAADMARAKALLGGPGEELEADTEYLDPFDAQPHPAPPDDGYMEPYDAQWVMSELPGRGVQLYDTPYEEQDPETADGPPSGQKPRQSRMPQEDERPADEYDQPWEWKKDHISRAFAVQFDSPEWERTPGSAKELRRPPPRSPQPAERVDPALPLEKQPWFHGPLNRADAESLLSLCKEGSYLVRLSETNPQDCSLSLRSSQGFLHLKFARTRENQVVLGQHSGPFPSVPELVLHYSSRPLPVQGAEHLALLYPVVTQTP
What is the function of this protein?
May function as an adapter protein.
What are the official names of this protein?
SH2 domain-containing adapter protein D.
Protein: PHS_XANOP
Sequence: MTDLIPLEQAHCLPRKGSDHKLGEARLAELLPQVPGWELAEAGMALTRTFRFPDYCRTLAFVNALAWIAHREDHHPDLGVHYDRVVVRYSTHDVGGLSENDFICAAKTARLYDQGITG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: FABZ_HELHP
Sequence: MDTNKIQGDKPIMNVEKIRQILPHRYPMLLVDRVMELVQNTSDSEPNGYIKAYKNVTINEEVFLGHFPNKPIYPGVMQIEGMAQAGGLLAFVSMFGDNVAEAKNKIVYFMTIDNVKFRIPVVPGDRLVYELKVLKHKGSIWQLGANAFVEDKLVSEAELKAMITEAKES
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFM3_MOUSE
Sequence: MNHTSQAFITAASGGQPPNYERIKEEYEVAEMGAPHGSASVRTTVINMPREVSVPDHVVWSLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDVTGAQAYASTAKCLNISTLVLSILMVVITIVSVIIIVLNAQNLHT
What is the function of this protein?
IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis.  Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes.  May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane.  Active against multiple viruses, including influenza A virus, SARS coronaviruses (SARS-CoV and SARS-CoV-2), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1), hepatitis C virus (HCV) and vesicular stomatitis virus (VSV) (PubMed:33270927).  Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV and SARS-CoV-2 S protein-mediated viral entry and VSV G protein-mediated viral entry (PubMed:33270927).  Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase).  Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.  In hepatocytes, IFITM proteins act in a coordinated manner to restrict HCV infection by targeting the endocytosed HCV virion for lysosomal degradation.  IFITM2 and IFITM3 display anti-HCV activity that may complement the anti-HCV activity of IFITM1 by inhibiting the late stages of HCV entry, possibly in a coordinated manner by trapping the virion in the endosomal pathway and targeting it for degradation at the lysosome.  Exerts opposing activities on SARS-CoV-2, including amphipathicity-dependent restriction of virus at endosomes and amphipathicity-independent enhancement of infection at the plasma membrane.
What are the official names of this protein?
Interferon-induced transmembrane protein 3, Dispanin subfamily A member 2b, DSPA2b, Fragilis protein, Interferon-inducible protein 15, Mouse ifitm-like protein 1, Mil-1.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Late endosome membrane; Single-pass type II membrane protein. Early endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. Cytoplasm, perinuclear region. Note=Co-localizes with BRI3 isoform 1 at the perinuclear region.
Protein: PGK_BORPA
Sequence: MSNVNTLSALAKSGALSGKRVFIRADLNVPFDDAGRISEDTRIRASVPGIRLALDAGEAVMVTSHLGRPKEGALTEADSLAPVAQRLSELLGMQVRLVPDWVDGVSVEPGEVVLLENCRGNVGEKKDDEGLSRKMAALCDVYVNDAFGTAHRAEATTHGIARFAPVACAGPLLEAELEALGRALHDPKRPLVAIVGGSKVSTKLSILQSLADKVDQLVVGGGIANTFMLAAGLPIGKSLAEPEQVEQARAVIEIMKRRGAEVPIPTDVVCAKSFGADAAATVKAAADVAEDDMILDIGPQTAQRLADILKAAGTIVWNGPVGVFEFDQFAHGTEVVARAIADSAGFSIAGGGDTLAAIAKYGIADQTGYISTGGGAFLEFLEGKALPAVAVLQARAA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIT_GEOTN
Sequence: MGVVHDVWVVTKQLLEATALPWPAEERETWLSQVDELLRRRERLLHKLRPPYSEEEQRLGREIVAWNQEIEARLRQVRDEIRDDLRMAGAKRQANAHYVHPYEQPLSFDGMFYDKRR
What is the function of this protein?
May act as an export chaperone for the filament capping protein FliD.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the bacillales FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TRBD_RHIRD
Sequence: MAESGSALVRSRVHRALSRPNLLMGADRELVLLTALAAIILIFVVLTWYAALFGIAIWLIVVGALRTMAKADPLMRRVYIRHISYKNFYRATSSPWRKF
What are the official names of this protein?
Conjugal transfer protein TrbD.
What is the protein family that this protein belongs to?
Belongs to the TrbD family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YIDD_CAMJJ
Sequence: MICLKILRFYQKFLSPLKPAACRYYPSCSEYALWQFQKKNFFLAFFSTFFRILRCNPFFKGGFDYPRVSKNFYPINLCFKPIFLAKKQLCFLYIPYKNKSFYLIKIIFKRTNQ
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PYRG_UREPA
Sequence: MEIDLMKHIQKTKFIFVTGGVYSSLGKGVSASSIGRILVELGYSVAMQKLDPYLNIDPTYLSPLQHGEVFVTKDGKEADLDLGTYERFINADLNKYASVTSGKIYYEILTKERENGFDGKTVQTIPHVTSAVIDYIKKIKDSLKTDFIIVEIGGTIGDIESLPFIEAISQFKTIYGVNNVMFIHCSPLIYIEKVGELKTKPTQHSVKTLRSLGINLDLLLLRTNQKLDEVTIKKLAWSCGLDIDMIFAAYDVESVYLLPNVLFEQGIHKTILDFFSLPLKNDNINSWIDFTDKITTFKKHNLVIGLVGKYVELPDAYKSVLASLELAAIELNIDLKIKYIQPQNLNENNINEELKKINGIVIPSIAGSIKGWPGALLAASYARKNNIPFLAVGTGVNIGIGEFINNVLKLPIEFINLGNGDFSFLKDAFVKNEIENYRIGEYCSNIQANTITSQIYLKQNQLNERHRHHFEFNNHYINNYFLNQNWKIGAISVDNNYIDVLEYTKNHFYVLTIFNPEYTSKPSKANPYFINLLKMSLKIKES
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
Putative CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: FBL61_ARATH
Sequence: MVDSKRMDSGSKDMINDLPDALLCHVLSYLTTKEAASTSLLSRRWRYLLAFVPNLEFDDSAYLHRDKRVKNPLHEKGLVGFVLTVDDKRKKLSTSFPDFVDRILDLQGNSPLDKFSLKMVDDHDPVDPDCVAPWIHKVLVRGVSDLHLVIDMNEWTSLPAKIFLTETLVKLTLKIRDGPPIDVKHVHLPKLKTLHLESVMFDEEDIGFSKLLSGCPELEELVLHHIWSCVWTSCSVSVATLKRLTFCCNNMKFCGMHEENPNNVSFDTPNLVYLEYAEVIANNYPKVNFDSLVEAKIDIWMTNDQLDEVRIRDIYEKNVMVGNATDLIVGIRNVRVLCLSADTLEVLTYCCKQIPIFNNLTHVTIQSTPKVGWKSLLKLLKNSPKLQTLVFQGLLHRDTKEEGVAIIKIEKQIEKVKHFLETMPHLEQLVLHYDSSIDGDMKQLLMLSSLASPKCKVQLIPLVT
What are the official names of this protein?
Putative F-box/LRR-repeat protein At3g59160.
Protein: TCPA_RAT
Sequence: MEGPLSVFGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIINTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAVKYTDIRGQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMLKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGASILSTLANLEGEETFEATMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDDKHGGYENAVHSGALDD
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit alpha, TCP-1-alpha, CCT-alpha.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: FABA_PSEFS
Sequence: MTKQNAFTREDLLRCSRGELFGPGNAQLPAPNMLMVDRITHISEEGGKYGKGELVAELDITPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFFLGWQGLPGRGRALGSGEVKFFGQVLPTAKKVTYNIQIKRVLKGKLNLAIADGSVSVDGREIYTAEGLRVGVFTSTDNF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POL2_ARMV
Sequence: RGLAGRGSVQVPKDCQAGIYLKTLDLRDMVSGFSGIQYEKWITAGIVMPNFKVVIRYPANAFTGITWVMSFDAYNRITSSISTTASPAYTLSVPHWLLHHKNGTTSCDLDYGELCGHAMWFGATTFESPKLHFTCLTGNNKELAADWEFVVELYAEFEAAKSFLGKPNFIYSLDAFNGSLKFLTIPPLEYDLSATSAYKSVSLLLGQTLVDGTHKVYNFNNTLLSYYLGIGGIVKGKVHVCSPCTYGIVLRVVSEWNGVTNNWNQLFKYPGCYIEEDGSFAIEIRSPYHRTPLRLIDAQSASSFTSTLNFYAISGPIAPSGETAKMPVVVQIEEIALPDLSVPSFPNDYFLWVDFSSFTVDVEEYVIGSRFFDISSTTSTVALGDNPFAHMIACHGLHHGILDLKLMWDLEGEFGKSSGGVTITKLCGDKATGMDGASRVCALQNMGCETELYIGNYAGANPNTALSLYSRWLAIKLDKAKSMKMLRILCKPRGNFEFYGRTCFKV
What is the function of this protein?
The movement protein is assembled into tubules that allow the transport of virions from cell to cell.
What are the official names of this protein?
RNA2 polyprotein, P2.
What is the protein family that this protein belongs to?
Belongs to the nepoviruses RNA2 polyprotein family.
What are the subcellular locations of this protein?
[Movement protein]: Host cell junction, host plasmodesma. Note=Assembles in tubules that are embedded within modified plasmodesmata. SUBCELLULAR LOCATION: [Coat protein]: Virion.
Protein: TRI1_PSEPG
Sequence: MIDLRSPNALLSDYVERYAHLSPEPSRQLQQRMDYNVRADAPAEPASKPRWLQSRACTLTPEQALDRAKGALLGLAIGDAVGTTLEFLPRDREHVNDMVGGGPFRLAAGEWTDDTSMALCLADTYVSQGKFDYATYANALVRWYRHGENSVNGRCFDIGNATRNALEGWLREGIGWQGNYDPSTAGNGSIIRLAPTAIFRRHSLSASWWESVTQSSVTHNADEAVNCCQLLAAQLHLALNGADKEETLAPAVRSLRPRPMIINAGEYKQKSRDQIRSSGYVVDTLEAALWAVWNSNNFHDAILLAANLADDADSVAATAGQLAGALYGVSGMPPEWVEKVAWSQHIQKLAQELFDRAPQVDELDALLYGKR
What is the function of this protein?
Immunity component of an interbacterial competition system (also called effector-immunity systems).  Expression in E. coli neutralizes the toxic effects of non-cognate S. proteamaculans effector protein Tre1 (Tre1-Sp); cannot be co-purified with Tre1-Sp from E. coli, suggesting they do not form a stable complex (PubMed:30343895).  Probably acts as an arginine mono-ADP-ribosylhydrolase, mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.  Probably de-ADP-ribosylates FtsZ and possibly other proteins; the ability to hydrolyze ADP-ribosyl moieties is not essential for neutralization of its cognate toxin, strongly suggesting its N-terminal extension occludes the active site of cognate toxin Tre1 (Probable).
What are the official names of this protein?
ADP-ribosylarginine hydrolase Tri1, Immunity protein Tri1, Tri1-Pp.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosylglycohydrolase family.
Protein: DSBB2_PSE14
Sequence: MYLARTRFLFFLASLACASIIGTAFYLQQTFGLDPCFLCLIQRAAIIACGVLALCAACHAPGPTGMRRYSLGFLLIALTGLVTAGAQVWLQTASADQLIPFITKLEHLLSLLSLDMCIDRLRSDAMFCAEITWTLFGISLPEWSLLAFTGLALLPLYPLFSEFSHWLATKDRARY
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B 2, Disulfide oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DRS13_PHYSA
Sequence: MAFLKKSLFLVLFLGLVSLSICDEEKRENEDEENQEDDEQSEMRRGLRSKIKEAAKTAGKMALGFVNDMAGEQ
What is the function of this protein?
Antibacterial peptide with activity against Gram-positive and Gram-negative bacteria (By similarity).  May also be active against fungi (Probable).
What are the official names of this protein?
Dermaseptin-S13, DRS-S13.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.