PharMolix/UniProtQA huggingface dataset:
Protein: MVP1_NEUCR
Sequence: MSLFGSSPPNDGSAALNPAKTANSSRSTLFDNEAPTTRSGSALFADDDHDSPWDMPTPRKQRSRADLIRNLLPSGDVPESYIETFDAVVRTENRSTNGRITAGGVARTLAAAKLGADDQARIMGIIAPASASATGAGGGGDGAHGGEANSSAAAAAAAVGLGDLGRNEFNVLLALIGLVQEGEVASLDGVDERRRNLPQPKLQGLVNENVQPMLPNLSELGAKPPQRPVTPPKAPTPSPPKQQQQQQHQPPTLRKVSMEYPEDPWNAPDLHKGHNHGPLEHSTGHNGAADVPRSVANDLNGNDAVSYSTSPEVTTTSSALPGRTTSTFTTSQPPSGPSSIHNVAESIQESNGAWNYFPGSSSGGGFGEPADNAITGPFGDSGGPGQSVSGSVGGSNPNRSIGHVRSGSNVEENILVTLMPEKEGVFMFQHHNYEVSSIRRGSKVVRRYSDFVWLLDCLHKRYPFRVLPLLPPKRVAFNGNHLSNDGAFIEKRRRGLARFLNALVRHPVLGQEQLVIMFLTVPTELSVWRKQATISVQDEFTGRTLPPGLEDSLPPTLEELFARTRVGVRRSAELYISTCTIMDRLIKRSEGVAADHARMAVSLISLTETSADTYATDHNDVPLLNDGLQAMGRHLRTAQTLMEDEAKAWEEGVLEDLKRQRDALVSLRDMFDRRDRLDKDNIPFLQRRIETNEAKLQALNAKPEGMVKPGEKERVVEAIIKDKESIVTQHNRSVFVKECIRDELRFFQNTQYNVSRLTQDWAQERVKYSEMLADNWRRLLDDLEGMPLGD
What is the function of this protein?
Required for vacuolar protein sorting.
What are the official names of this protein?
Sorting nexin mvp1, Vacuolar sorting protein 1.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MURC_HAEIE
Sequence: MKHSHEEIRKIIPEMRRVQQIHFIGIGGAGMSGIAEILLNEGYQISGSDIADGVVTQRLAQAGAKIYIGHAEEHIEGASVVVVSSAIKDDNPELVASKQKRIPVIQRAQMLAEIMRFRHGIAVAGTHGKTTTTAMISMIYTQAKLDPTFVNGGLVKSAGKNAHLGASRYLIAEADESDASFLHLQPMVSVVTNMEPDHMDTYEGDFEKMKATYVKFLHNLPFYGLAVMCADDPVLMELVPKVGRQVITYGFSEQADYRIEDYEQTGFQGHYTVICPNNERINVLLNVPGKHNALNATAALAIAKEEGIDNEAILEALADFQGAGRRFDQLGEFIRPNGKVRLVDDYGHHPTEVGVTIKAAREGWGDKRIVMIFQPHRYSRTRDLFDDFVQVLSQVDALIMLDVYAAGEAPIVGADSKSLCRSIRNLGKVDPILVSDTSQLGDVLDQIIQDGDLILAQGAGSVSKISRGLAESWKN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_ACIBC
Sequence: MSTENTNTAVAEEIPNLLITPSAQEYLHELLAKQNTPGIGVRIFVEHPGTPRAECCMAYSAPEEVVPTDYKQDYPDFPAYIDAPSIPYLLDAVIDYNKDRFGGQLTFRAPNSKVPRVGPDASIEERITYVLQAEINPGLAGHGGNCSLVEVQDDPEHGLTAVLKFGGGCQGCSAIDVTLKQGVETTLKEHIPELQRVVDQTDHTQAEGAYFK
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: MSLN_RAT
Sequence: MALPTAQPLLGSCGSPICSRSFLLLLLSLGWLPLLQTQTTRTSQEAALLHAVTGTVDFASLPTGLFLGLMCDEVSGLSMGHAKELAMAVRQKNIVLQVHQLRCLARRLPKHLTNEELDALPLDLLLFLNPAMFPGQQACAHFFSLISKANVNVLPRRSLERQRLLTGALKCQGVYGFQVSETDARALGGLACDLPGEFVAKSSEVLLPWLARCGGPLDQGQAKAVREVLRSGRAPYGPPSTWSVSTLDALQGLLVVLDESIVHSIPKDVITEWLQGISREPSRLGSKWTVTHPRFRRDTEQKACPPGKEPNVVDENLIFYQNWELEACVDGTLLAGQMDLVNEIPFTYEQLSIFKHKLDKTYPQGYPESLIKQLGHFFRYVSPEDIRQWNVTSPDTVNTLLKVSKGQKMDAQVIALVACYLRGGGKLDEDIVKALDNIPLSYLCDFSPQDLHAIPSSVMWLVGLHDLDKCSQRHLGILYQKACSAFQNVSGLEYFEKIRTFLGGASREDLRALSQHNVSMDIATFKKLQVDALVGLSVAEVQKLLGPHIGDLKTEEDKSPVRDWLFRQQQKDLDSLGLGLQGGIPNGYLILDFNVREAFSSGAPLLGPGFVFAWIPALLSALRLS
What is the function of this protein?
Megakaryocyte-potentiating factor (MPF) may potentiate megakaryocyte colony formation.
What are the official names of this protein?
Mesothelin, Pre-pro-megakaryocyte-potentiating factor, Protein expressed in renal carcinoma.
What is the protein family that this protein belongs to?
Belongs to the mesothelin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Golgi apparatus. SUBCELLULAR LOCATION: [Megakaryocyte-potentiating factor]: Secreted.
Protein: NS3B_BCHK4
Sequence: MDYVSLLNQFWQKQIKSYKETPSQYHYLYPPRFFYKPVLGNLQHPTKWCCTIKFYEYSAQATECTKASAKQDAARLICEQLQAAGLLNGMELRFRSSASDIFGQNRYDASKSYFFSKTA
What is the function of this protein?
Induces host cell G0/G1 arrest and apoptosis.
What are the official names of this protein?
Non-structural protein 3b, ns3b, Accessory protein 3b.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host mitochondrion.
Protein: GCH1_LISW6
Sequence: MEQIDKQKIADAVKVILEAVGENPEREGLIDTPMRVARMYEEVFSGLKKDPSIHFDTIFAEQHEELVLVKDIRFSSMCEHHLVPFFGVAHVAYLPQNGRVAGLSKLARVVDDVSKRPQLQERITTTVAEIMMDKLKPLGVMVIMEAEHMCMTIRGVNKPGTKTITSAVRGAFKNDDKLRSEVLALIKHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RL24_SALPB
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: KIRR2_MOUSE
Sequence: MLASALLVFLCCFKGHAGSSPHFLQQPEDMVVLLGEEARLPCALGAYRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQASQAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDSRPAPELLWFRDGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSHDDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAEPQTVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADATFLTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKSVSVDVGKDASFSCVWRGNPLPRITWTRMGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGLGGGKAQARLTVNAPPVVTALQPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRRDLLPTVRIVAGAASAATSLLMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSSRGPEEETGSSEDRGPIVHTDHSDLVLEEKEALETKDPTNGYYRVRGVSVSLSLGEAPGGGLFLPPPSPIGLPGTPTYYDFKPHLDLVPPCRLYRARAGYLTTPHPRAFTSYMKPTSFGPPELSSGTPPFPYATLSPPSHQRLQTHV
What is the function of this protein?
May regulate basal insulin secretion.
What are the official names of this protein?
Kin of IRRE-like protein 2, Kin of irregular chiasm-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localized along the sites of the cell contacts (PubMed:26324709). Colocalizes with E- Cadherin and beta-catenin (PubMed:26324709).
Protein: RL14_MOUSE
Sequence: MVFRRYVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDFILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRNRIIKTEVKKLQRAAILKASPKKAAVAKAAIAAAAAAAAAKAKVPAKKATGPGKKAAGQKAPAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
60S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RASD_DICDI
Sequence: MTEYKLVIVGGGGVGKSALTIQLIQNHFIDEYDPTIEDSYRKQVSIDDETCLLDILDTAGQEEYSAMRDQYMRTGQGFLCVYSITSRSSYDEIASFREQILRVKDKDRVPLILVGNKADLDHERQVSVNEGQELAKGFNCPFMESSAKSRINVEEAFYSLVREIRKELKGDQSSGKAQKKKKQCLIL
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
What are the official names of this protein?
Ras-like protein rasD, Transforming protein p23 homolog.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ARCA_STAA2
Sequence: MTDGPIKVNSEIGALKTVLLKRPGKELENLVPDYLDGLLFDDIPYLEVAQKEHDHFAQVLREEGVEVLYLEKLAAESIENPQVRSEFIDDVLAESKKTILGHEEEIKTLFATLSNQELVDKIMSGVRKEEINPKCTHLVEYMDDKYPFYLDPMPNLYFTRDPQASIGHGITINRMFWRARRRESIFIQYIVKHHPRFKDANIPIWLDRDCPFNIEGGDELVLSKDVLAIGVSERTSAQAIEKLARRIFENPQATFKKVVAIEIPTSRTFMHLDTVFTMIDYDKFTMHSAILKAEGNMNIFIIEYDDVNKDIAIKQSSHLKDTLEDVLGIDDIQFIPTGNGDVIDGAREQWNDGSNTLCIRPGVVVTYDRNYVSNDLLRQKGIKVIEISGSELVRGRGGPRCMSQPLFREDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QSEB_HAEIN
Sequence: MRILLIEDDNLIGNGLQIGLTKLGFAVDWFTDGKTGMAALTSAPYDAVVLDLTLPKLDGLEVLQQWRSNHQDVPVLILTARDTLDERVKGLQSGADDYLCKPFALAEVAARLQALIRRRYGYHHSVIEQAGVKLDQNQRSVWLNNQPISLTSREYKLLELFMLNKDRVLSRSSIEEKLSSWDEEISSGALDVHIYNLRQKLGKQFIRTVHGVGYALGQVEK
What is the function of this protein?
Member of a two-component regulatory system QseB/QseC.
What are the official names of this protein?
Transcriptional regulatory protein QseB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX1_HETPN
Sequence: MKIAIVMTLLLVAFSTASFAIEPIERAALDLVMARADSGGDAGGDAGADDEGSCKWMFQSCEPPAKCCDGWTCYKGRCNLILGR
What is the function of this protein?
Weakly nhibits voltage-gated sodium channels Nav1. 7/SCN9A.  High concentration of the toxin (3 uM) inhibits Nav1. 7/SCN9A currents by 79%.
What are the official names of this protein?
Mu-Sparatoxin-Hp1, HptTx-208.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family.
What are the subcellular locations of this protein?
Secreted.
Protein: APAH_BORPD
Sequence: MKGSIWMIGDVQGCCAPLEQLLAHPDLAGDPDARFWFAGDLVNRGPQSLASLRRIIGLGERAVAVLGNHDLHLLAAAAGVRKPSKSDTIGEILQAPDADDLVDWLRHRPLAHFEQGHLLVHAGVLAKWDVAKTLALAGEVQEALRGPNWQKALQKMYGNEPVHWKEHHKGGKRMRVIINALTRIRLCTPAGHMEFATKVPPGAWPAGLMPWFDVPGRATRDITVVFGHWSTLGLLLRPDVICLDTGCVWGGSLSALRLQDRKLVQIKCSQFQDPLAD
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: VLPA_MESHY
Sequence: MKKSIFSKKLLVSFGSLVALAAIPLIAISCGQTDNNSSQSQQPGSGTTNTSGGTNSSGSTNGTAGTNSSGSTNGSGNGSNSETNTGNKTTSESNSGSSTGSQAGTTTNTGSGSNSESGMNSEKTENTQQSEAPGTNTGNKTTSESNSESGMNSEKTENTQQSEAPGTKTENTQHTS
What is the function of this protein?
Responsible for the antigenic diversity for host adaptation.
What are the official names of this protein?
Variant surface antigen A, VlpA prolipoprotein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TGFA1_HUMAN
Sequence: MMSIKAFTLVSAVERELLMGDKERVNIECVECCGRDLYVGTNDCFVYHFLLEERPVPAGPATFTATKQLQRHLGFKKPVNELRAASALNRLLVLCDNSISLVNMLNLEPVPSGARIKGAATFALNENPVSGDPFCVEVCIISVKRRTIQMFLVYEDRVQIVKEVSTAEQPLAVAVDGHFLCLALTTQYIIHNYSTGVSQDLFPYCSEERPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVSFPYVIALDDEFITVHSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASRRVEEALVLAKGARRNIPKEKFQVMYRRILQQAGFIQFAQLQFLEAKELFRSGQLDVRELISLYPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKMAKCKRFLMSYLNEVRSTEVANGYKEDIDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNNQDAAAVQLWVNIVNGDVQDSTRSDLYEYIVDFLTYCLDEELVWAYADWVLQKSEEVGVQVFTKRPLDEQQKNSFNPDDIINCLKKYPKALVKYLEHLVIDKRLQKEEYHTHLAVLYLEEVLLQRASASGKGAEATETQAKLRRLLQKSDLYRVHFLLERLQGAGLPMESAILHGKLGEHEKALHILVHELQDFAAAEDYCLWCSEGRDPPHRQQLFHTLLAIYLHAGPTAHELAVAAVDLLNRHATEFDAAQVLQMLPDTWSVQLLCPFLMGAMRDSIHARRTMQVALGLARSENLIYTYDKMKLKGSSIQLSDKKLCQICQNPFCEPVFVRYPNGGLVHTHCAASRHTNPSSSSPGTRT
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway.  Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.  The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290).  Functions predominantly in APPL1-containing endosomes and in degradative but not recycling trafficking of endocytosed cargo (PubMed:25266290).
What are the official names of this protein?
Transforming growth factor-beta receptor-associated protein 1, TGF-beta receptor-associated protein 1, TRAP-1, TRAP1.
What is the protein family that this protein belongs to?
Belongs to the TRAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome. Note=Colocalizes with TGF-beta receptors in the absence of signaling.
Protein: RNH2_THESQ
Sequence: MGIDELYKKEFGIVAGVDEAGRGCLAGPVVAAAVVLEKEIEGINDSKQLSPAKRERLFDEIMGKAAVGIGIASPEEIDLHNIFNATKLAMNRALENLSVGPSFVLVDGKGIELRVPGTCLVKGDQKSKLIGAASIVAKVFRDRLMSEFHKMYPQFSFHKHKGYATKEHLNEIRKNGVLPIHRMSFEPVLELLTDDLLREFFEKGLISENRFEHIKNLLEAKKSVVFRKERTDHNLPLF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP10_SCLS1
Sequence: MPRRAASPALSENDFDITKSLFNDDIDGNDDDFGNTTTKNVEPLDANGILDLGLESDGDGDGAFISAQQAAANRKASNLKGQSVKKGGGFQAMGLNSHLLKAISRKGFNVPTPIQRKTIPLVLDNQDVVGMARTGSGKTAAFVIPMIEKLRAHSVRVGARALIMSPSRELALQTLKVVKEFGRGTDLKCVLLVGGDSLEEQFGFMAANPDIVIATPGRFLHLKVEMSLDLSSMKYVVFDEADRLFEMGFAAQLGEILHALPISRQTLLFSATLPKSLVEFARAGLQEPSLVRLDAESKVSPDLQSAFFSVKGAEKEGALLHILQDLVKMPTGLPENALNATDNFSKKRKRGPDGPTKKLKPTEHSTIIFAATKHHVDYLASLLRMSGFAVSHAYGSLDQTARNIQVEDFRTGKSNILVVTDVAARGIDIPVLANVINYDFPPQPKVFVHRVGRTARAGQRGWSYSLVRDTDAPYLLDLQLFLGRRLLLGRDCGDSPNYAEDVIVGALQRNEVESKSEWITKLLYDDDDLTALRNVAGKGEKLYVKTRNSASSESAKRAKEVVASKGWMELHPLFKDVTNGAEQARLEMLAKISGFRPNETVFEIGQKGKAAHSEAAEIMRHRREKIIPRRQKEEDEKAAAAAAAAEEDNFDSPAEENDDNDDLEVTVTGGDDDMAEASDGELEVTFSKAAQKGKGRTLSWKDSENFMSYTPKTINTAEERGYGVHSGSYNTASQNSNFVEAARGVTMDLTNDDGAKSFAEPSKAKGMRWDKKNSKYVARANDEDGSKGIKYIRGESGQKIAASFQSGRFDRWRKAHKVDRMPRTGEAEREGPASAGGVGRGFGTRYKHKQERAPKEADKYRDDYHVRKKRVAEAKENRVGSFKDGSGKSEIKSTEDIRKDRKLQERRKAKNARPSKKGKY
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: KDSA_DELAS
Sequence: MKLCGFDVGLDRRFFLIAGPCVVESEQLQMDVAGHLKEITAALGIHFIFKSSYDKANRSSGASFRGPGMDKGLEILAKVKKDLQVPILTDVHTESEIPAVSQVVDVLQTPAFLCRQTDFIRAVAQSGRPVNIKKGQFLAPHDMKNVIDKARAAAKEAGLPEDSFMACERGASFGYNNLVSDMRSLSIMRETGAPVVFDATHSVQLPGGNGTSSGGMREMVPVLSRAAVAVGVAGLFMETHPNPPCALSDGPNAVPLKHMKALLETLVALDDVTKKNGFLENDFGV
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_BAUCH
Sequence: MSKIILDLQVACDHRCNLPSEDLFMYWLYMVLPLFRKKAEVTIRLVDEAESYNLNKIYRGQNHSTNVLSFPFKAPSPVKLVLLGDIIICRQVVEREAQEQNKILEAYWAHMVIHGSLHLLGYDHFIEQNAKKMEYLETKIMHKLGYLNPYETEIS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_SALA4
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLSDRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLSVTEDELVRVNMGEPNFEPAQVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDNVDTAAVETLGPVLESHERFPERANIGFMQVVRREHIRLRVYERGAGETRACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAAHIYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPT1_RAT
Sequence: MDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPDASARTTQTLTIERRGVEIEEGGIKVKLTLVDTPGFGDSVDCSDCWLPVVRFIEEQFEQYLRDESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALLPRETQVLKQKIRDQLKEEEINIYQFPECDSDEDEEFKKQNEEMKENIPFAVVGSSEVVREGTRPVRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARDRASRSKLSRQSATEIPLPMLPLADTEKLIREKDEELRRMQEMLEKMQAQMQQSQAQGEQSDVL
What is the function of this protein?
Filament-forming cytoskeletal GTPase (By similarity).  May play a role in cytokinesis (Potential).
What are the official names of this protein?
Septin-1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis (By similarity).
Protein: ATG9_PODAS
Sequence: MPRKLFSKMPTTQGRSFYEELRGHDSEGYDGGSRAGLLDEENLNHNFQDYDLDHAEGLTVDDSRATLAGLRKTPASKVPPGHQNDRSMWLAHDDDADNDVPPSLLVEPRGAHLAGKPKRKQSRQAAYTMPGSSNTRAQWETIQAHQPLHNDEPFTQSHRGNGAPGSLFSGSASLDAKKMAEWRWANVQNLDKFIKEVYDYYRGCGIKAIITERVLHLGNVAFIAVLLTFLTQCVDYSLVRGSQKLSQIIVPQCTRKMSGWWNLGLWLFAFYFIWKAIQYILDLHRLFHVRDFYTHLLNIPDHDMQTITWQEVVARVMALRNQNSKTATTLTPLQRHFIGSQSKERLDASDIANRIMRRENYLIALFNKDILDLTIPLPFLRNRQYFSRTLEWTLMFSVLDMVFDEKGQVNQKFLRADRRGEISEKLRSRFQFAGIMILVLSPFVSLYLVIYYFLMYYHEIQKNPSVLSSRSYTPLAEWKFREFNELPHLFQKRLDMSKAFATHYMDQFPKVKTEMVAKSVAFVSGALATVLAIASVFDPELFLGFEITPDRTVLFYTAIFGSIWAVAHGMQSQDDVVFDPEYAMRNVIEYTHYEPDHWKDRLHSYDIKLEFAELYKPKIVIFLEEILGILTTPFVLFFSLPKCSDQIIDFFREFTLHIDGLGYVCTFAEFDFKKAMANAKKPSDGGDVRDEYYSAKHGKMEASYYGFIGNYGNFALNPKGAPGSHLPPGMRNQFHPPPAWPGLNSPPLGADMQTSRMGRSEFRSRSRAPGQGLRPGPSMVAPSPMASILLDPHHLPPSHLVNPGRASHPHRVQQNRRPGESNIIEESLEDEERGREGVNRHDDEEVYGHGDGMDESAWQTSPARTLSRDNSAIEGTGTAEAGVVDMIYQFNQAQFTRNGV
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PCKA_SALSV
Sequence: MRVNNLTPQDLKAYGINDVQDIVYNPSYDTLYQEELNPGLEGYERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTLWWSDKGKGKNDNKPLSQETWQHLKGLVTHQLSGKRLFIVDAFCGANADTRLSVRFITEVAWQAHFVKNMFIRPTDEELVGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERIQLIGGTWYGGEMKKGMFSVMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYHAIRRDALLENVTVREDGTVDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTANQTQYHFLSGFTAKLAGTERGVTEPTPTFSACFGAAFLTLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFRLPLFDLAIPTELPGVDTHILDPRNTYASPEQWQEKATALAKLFIENFEKYTDTPAGEALVSAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGKH_DROSI
Sequence: MSHLKLDTLHVQRSPRGSRRSSRSSGRSSACSSGSISPVPIIPIISISHDGDESESESEIETEPARLFQRRMSIKCTNNLAAIIKEGFLLKHTWSFQRWRRRYFRLKRNMLFYAKDEKCDVFDDIDLSDLCYFECGIKNVNHSFQIITPTRSLVLCAESRREMEDWLGSLKTATAPQRPRGDSFLIEQHDILSNHHHWYATSHARPTYCNVCRDALSGVTSHGLSCEVCKCKVHKRCAAKSIANCKWTTLASVGKDIIEQADGSIIMPHQWMEGNLPVSSMCAVCKKTCGSVLRLQDWRCLWCRATVHVACRPQMAVACPIGPAKLSVVPPTSVHSISTDDAWDVASPKGNFSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLISTGPSLGLRLFRHFEMFRILVCSGDGSVGWVLSEIDRFNMHKQCQVAVMPLGTGNDLARVLGWGSSCDDDTHLPQILERYESASTKMLDRWSIMVFEKAIPVPKTPKMSISTEQEAMLTGMVTSANHHLRFIVETNDTQTLISSTRNLCDTVDDLVCRISEHHKDDEQLAVKCDILRQKLNMLLDALQEEEIGAHSGDDLIATIRSLIARSIPVTPGSNAYLLNPNISIEKTEKDQINSKERRNSRSLRSSEKEALQCRANSVKRAIYNVVEHSEPGRPKRYQRKLSITPFEALKLPTNASGESTPCTSPLPIIPPINIISPTMETSRLTCISPLPDTRRDSVDENFFNSINLPAPRQFADSRRSSGVPEVIQEIEEGANGETVYRRSRMSLTGGANIDDAGNRLSPCSDGGENTPTERKVDFLRVPIHTGEPIVDPLCDYRPHEVFEQKENDKEKDKPVEIDMERDTCVEKDGSVPEEKLVHTCNIQVPGVVVTPNPQNVYSSASITIIDTDAQTTTEQSSSDDLGGEASDVLSAISNEECSVASEIFDKQDAGQTVGDIIQNMDASNFTHIDSPETSDETEAMPGESIMDDISSVLGHDITYALQDNTLTDDTTTLCSEHVGPPKPPRKKSLSALSRTQAHPRRRNSSPPRIARLARMDSDDNPQQFGFENIVFEIDNRCDDQKMREPPRYCSLAQFVEGNDIARQSFKQLMLEQHRGEDNDSEYPEHQQTPTNKGANLLATTSEDELSTQTAIKIEIQDIDATVRNLNSSMKPNTILTTSTSPTKKSGHGQDISVVVRPPTPLRGDSIKPTVSLLPVSSGGAMAVSMTCSGMLGVRAMNASEIRRHSSHAPGLAVREFDKDKDRRHSGFNPNQLTLDPEHARFLSSSPAASRRISCGSLFKVKNKKIATKRSYGLFSVRFFVVAEPDFRLATLALIRPLIPLPNEALPNLQTLKGSKSSLFMGSTLFGFDHLASAERDKEEKGGKDKEKTPTEETNRKLPIINPLVRLPNWPNLANGGGFISKCLLANADTLCAAVSPLMDPDETLLAGYHEKCVMNNYFGIGIDAKISLDFHNKREEHPEKCRSRARNYMWYGVLGSKQLLQKTCKNLEQRVQLECDGQRIPLPELQGIVILNIPSFMGGTNFWGSSTKKDDIFLPPSFDDRVLEVVAVFGSVQMAASRLINLQHHRIAQCQSVQINILGDEEIPIQVDGEAWLQPPGMIRILHKNRVQMLCRNRSLELSLKSWQEKQRQHSISIQRDASSTASEHANSTDEVISERECYVLLNFIEAVSSLVKWVKFLIISHPALQHDLYEVACRASEALESIHPQGKLLEGPSLRTKLVEVIDSSRQLYDDACTLLRDRGHSLILREDLETKLSAALANMEMELKKCSVQKCIDGKLRAYFNVLAPNEEVDGRRKSRPFWVRLRSGSTAGQQQFKPPMTNTREAANNWSVNEVVTWLETMQLSEYVDSFLKNDIRGKELLTLGRRDLKDLGVVKVGHVKRILQAIKDLSEN
What is the function of this protein?
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).
What are the official names of this protein?
Diacylglycerol kinase eta, DAG kinase eta.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_STRCO
Sequence: MSRAGLEVLIRRVDPDVPLPAYAQPGDAGADLRTTVERELAPGERAVLPTGVSVALPEGYAAFVHPRSGLAARCGVALVNAPGTIDAGYRGEIKVIVVNLDPRESVRFERFDRIAQLVVQQVERVRFRQVAELPGSARAEGGFGSTGGHAGLDPASGTSGQVAEGGPTGGNRYASVVSDREGQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.