PharMolix/UniProtQA huggingface dataset:
Protein: VME1_BEV
Sequence: MFETNYWPFPDQAPNPFTAQIEQLTATENVYIFLTTLFGILQLVYVMFKLLCTMFPSLHFSPIWRGLENFWLFLSLASLAIAYWWLPSMTFTGYWALTIIATILVFILLIMMFVKFVNFVKLFYRTGSFAIAIRGPIVLVALDVTIKLHCTPFAILVKEIGNIFYLSEYCNKPLTAAQIAALRICVNGQWFAYTRSSTTSAARVAAANSTAKYHLFVLQGVAEYTQLSSVKFE
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: GTAB_STAAN
Sequence: MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQEVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNNDNQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKALGL
What is the function of this protein?
Catalyzes the formation of UDP-glucose from glucose-1-phosphate and UTP.  This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i. e.  the predominant glycolipid found in the S. aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA) (By similarity).
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, Alpha-D-glucosyl-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, Uridine diphosphoglucose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: RHO1_KLULA
Sequence: MSQAVGNVASIRRKLVIVGDGACGKTCLLIVFAKGKFPQVYVPTVFDNYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICYSIDLPDSLENVMEKWISEVLHFCQGVPIILVGCKADLRNDPQVVEELRAQGLQPVSQAQAQEVADQIGAVDYIECSAKTGYGVREVFEAATRASLVGKQGKSKPKTKSSKKKKCVVL
What are the official names of this protein?
GTP-binding protein Rho1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RIBC2_MOUSE
Sequence: MEVAMSKDLQQEANLAKKRYIDLCRQGRIFDARNRIIGGDTQAWDFQVRDQKIKEITDKARHEAFAAEMKHNDKVMCMAHDREQRHRKQLCRAINDFQQNFQKPETRREFDLSDPLALQKELPARISDNDMRNTISGMQKFMGEDLNFQERRRFQKEQSREWFLQQHGEREKARADHLLAEHLHTQTRLKFDETARELMKLEGSTRKEVCAAVKAFNKNQVVELTERKRQEKQQEQEDNMTEITNLLHGDLLSENPRPVASSFGSHRVVLDRWKGMNREQLEEIWFTQKRQIQEKLRLQEEERQHSMDWDLRRIRKAHASLLHERQQQRLLREQRRALDCSNLNLARQQYLQKKQMNTASSSQPTEDYFSQFNTRSR
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
RIB43A-like with coiled-coils protein 2.
What is the protein family that this protein belongs to?
Belongs to the RIB43A family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: ACTP1_PHYSE
Sequence: MRHFVVFLYMFLALSIPTAFAKKHIVTKKGNHQDITNDNEGENAEKKSAAVAGAVIAGGELALKILTKILDEIGKIDRKIAIGVDNESGLKWTALNTYYKSGASDVTLPYEVENSKALLYTARKSKGPVARGAVGVLAYKMSSGNTLAVMFSVPFDYNLYTNWWNVKIYDGEKKADEKMYNELYNNNNPIKPSIWEKRDLGQDGLKLRGFMTSNGDAKLVIHIEKS
What is the function of this protein?
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers.
What are the official names of this protein?
DELTA-alicitoxin-Pse1a, DELTA-ALTX-Pse1a, Cytolysin PsTX-20A, Pstx20, ptx20a.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: F90AJ_HUMAN
Sequence: MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLKFPKKPRLGPFQIPESAIQGGELGAPGNLQPPPAATELGPSTSPQMGRRTPAQVPSVDWQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE
What are the official names of this protein?
Protein FAM90A19.
What is the protein family that this protein belongs to?
Belongs to the FAM90 family.
Protein: SYP_MYCPN
Sequence: MANKDQNLTLWYDQLLSKAQLVSYGDVKGTNCFLPNSWNLWLQIQRLYNNATALIKLKDKVILKQFIPIEPLPYTVEQVQLPTLSFYSEYQKEKRHVEGFNPELFLIEQIGTKKLHDPLVLRPTSEIAFCNLWKKQSFSYQNLPVIYNQWTCVFRAEKNTRPFLRNSEFYWQETHGLFSDGVNSESAAIAFWKLYQDIIVNQLCIPAFVGLKSPNERFAGAQNTWTVESIMPDGQALQCATSHDLGQTFTKPFGLTFQNQANQQAIPYSFSCGISTRILGALLLTHSDDFGLVLPWKVAPIQVKLYLFDKKGDTKTVELAQKVQTLLEQLAIRFQFIKVENQLGKQLGQGEVNGIPFQLIVDNPQTVNIFNRLTRVKTAYSFEQLASRFVELVQQYHQAMYDKAKAVVQQKVVQATTLKQIEQAFNDKKAVLCAVRLTDTLEQQLKERYQVTVRCCLEQLQKPQICPFSGESAQDYVLIARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI4_DICDI
Sequence: MALSLYYDEDDDENENENKDKPNNDFKNQQQINTSKTTNNNNNINNKNNYNNKFNDDDIFNNDKIITKPRVTTTTTTTKNTSTNSNINKTKFNDDDIFDDEDEDSNSNKTTTTTTTTTTTTDTIITNDYRYQKTVPFSSFCDLMNRIINDTKISNKKNYLEKFMNHYKDEPNNFYQLLRLILPQLDKDRNSYGLKEKTLARLYVELLNISPESVDAMRLLNWKKSTNDEIGGDFGTAVYLSLKNRCNNDNGRIKVSMGDINESLDQLSQPLTDKKTKVSILKKVLRSTTAQEQKWFVRIILKEMKNGLSDNITLKFFHPDAIDHFNITSNLRLVCTNLFYMTQSKQKELKDKQKLEEKENLLKQQQQQQNDLDIYKLEIKLFNPIKPMLANRQSIDNLSMILNSAISATQFVVEKKFDGERIQIHKDGEQVKYFSRNSNDSTGIYGSMFTPIVKECVLAERCILDGELIVWDSISQRFEDFGNLKTLALNKDGISGSGDPLGINYGKQLCFIAFDILFVKDQSVMNLPLMQRLMLLKRCVTIKSKQFEISEQTTVNSISQIISLLESAIINREEGLMLKNLHSLYVPAERKDKWVKIKPEYIDGMGNGADDLDLVIIGGYYGSGLNRRGGTISHFMLGVPFIADSTDTDIDDESTFDKNVIFYSFCKVGSGYTDIQLKSLQKDLDPHWNNFSTSKPPSIIQLAEPFKEKPDVWIDPRVYSKVLQIKASQIVVTDKYKCGYTLRFPRVLKIRDDKGWKDCCSHEEIIDLFTNYSTNLNFKRDHEYGDGSGGKNKKLKKSKKTTNQLLADSGLKVLSIFQDTDTSGIIPTQNIFQGIEICVIKGSSGEYTKSKLEIMIVEMGGSKVQYPSRNTNYVISSKEVVKIQNLIQSGFIDIVSFNWIVDCYNEKRLVPLGPKYMIFSTESTKKRFLLDSDQFGDSYINETTEQSLKDSFNQIDKLKLKKQLSINSTTTTTTTSISKYFSNCWWSLFKEFTFYLDLYQVVGEKSTLIENNNLELSNLNIQFYGGKISIEFNNKITHVVLDSLDLSRITFIKNKINSLSLPIQIVTTNWIQLSINNYSIQPILEILD
What is the function of this protein?
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction.  Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair.
What are the official names of this protein?
DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NAGK_SALA4
Sequence: MYYGFDIGGTKIALGVFDSTRRLQWEKRVPTPHTSYSAFLDAVCELVAEADQRFGVKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLVLNGKPITGQSYITGEFGHMRLPVDALTLMGFDFPLRRCGCGQMGCIENYLSGRGFAWLYQHYYDQSLQAPEIIALWEQGDEQAHAHVERYLDLLAVCLGNILTIVDPDLLVIGGGLSNFTAITTQLAERLPRHLLPVARAPRIERARHGDAGGMRGAAFLHLTD
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: YOYD_BACSU
Sequence: MVKKALIVILILLPFVQLALLPLVNRIEPIMFGLPFFHFWLLLWIIVTPLCSFGIYQMQKKDGGLE
What are the official names of this protein?
Uncharacterized membrane protein YoyD.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YHGN_SHIFL
Sequence: MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVRELLIALLVMLVFLFAGEKILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAGEEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFLRLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG
What are the official names of this protein?
UPF0056 inner membrane protein YhgN.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FENR_LACLA
Sequence: MQELDLIIVGAGPVGLYAAFYAGMRGLSVAIIESAQVPGGQPQNLYPEKLIYDIAGLPAVTGADLTKNLLEQLAQISHRLFLGESVQKIEKEEGIFSVTTDKSTRRAKGVLLTTGAGLLKPRKLGIDNEETLANEGKISYFITSLKEFEGKNVAVFGGGDSALDWSLMLEKVAKNVHLVHRRTAFRGHEITVDRVMNSNVQVHTPYTFSNLIENELELKKIKSEESLNFSIDKILVNYGFLTNQVTLAENLEVSRNGRVKADSMMQSNIEGLYVAGDASDYPGKMPLMSVGFGEAVHAINAMTKKLEFDHPLRGGHSSSIF
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: DNAJ_LACLA
Sequence: MNNTEYYERLGVDKNASQDEIKKAYRKMSKKYHPDLNKEEGAEEKYKEVQEAYETLSDEQKRAAYDQYGEAGANGGFGGGGFGGASGFSGFGGGSGGFGGFEDIFSSFFGGGGAQVNPNAPRQGDDLQYRINLKFEEAIFGVEKQVKYNREELCHTCGGSGAKAGTHPETCHKCGGRGQINVVRDTPLGRMQTQVTCDVCNGTGKEIKEKCETCHGSGHEKVAHTVKVTVPAGVETGQKMRLQGQGDAGVNGGPYGDLYVVFQVEASDKFERDGAEIYYKMPMDFVQAALGDEIEVPTVHGNVKLKIPAGTQTGANFRLKGKGAPKLRGSGNGDQYVIINIVTPKNLNQAQKEALQAFAKASGVEVSGSGKKGFFDKFK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX20A_LYCSI
Sequence: MSSKVQAVLLLVGVITFLAVHAQEELSENTESERSCARLYERCSMTRRPCCNNVPYVCSLLGTYCECKKGLIQTVGDFIGI
What are the official names of this protein?
U17-lycotoxin-Ls1a, U17-LCTX-Ls1a, Toxin-like structure LSTX-P3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTNA_METCA
Sequence: MSDHSFSAVSAVQALKWSDGGLEVLDQRLLPGDVVYQIFDTAAGVAEAIASMRVRGAPAIGIAAAYGVVLGARAAYARDPAHWKRAVEDDIAVLARSRPTAVNLFWALERMREAMAAIEGDPVPALLAAARRIHEDDLAANLAMGELGAAILGGCKGVLTHCNTGALATGGYGTALGVIRSTWRRGALERVYATETRPWSQGARLTVWELGQDRIPATLLADSAAAWLMKSGAVQWVVVGADRIAANGDVANKIGTYSLAVLARHHGVKLMVVAPISTVDWATATGEDIVVEERDPRELLHPLFLGSDSVIGAWNPVFDVTPAALIDAIVTEAGVVTNPSPDTMATLRGKAR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: HEPS_ASPOR
Sequence: MISMSVPRKKQEREISLLMHYVDDVFPHQFPIYHSQFVGKREWLLPLLSSTRSVYYATLCLSLLHKEKSSNLDQPGSVSFCQEERLRYYILALRETQQLLQQLSPVCDLEAMRSCVPSLASALHLISYESSCPVYGDWKVHLQAATSLIPILVGGWNSMIKPIKHTSTLWTGLTLSDFHDLHTEGSLSYEDASALRFLTNALAVTGILSFISTGPTSALSDYRYLMDATCDMVQCDQFLGCENWVMSAILDVGLLDRWKREEEGNRRLSFRELANRAKRLEDCLENGIRELSAKTSGSSDAVSSITRIYASSTLTYLHSVVSGLNPDLSEIQESVSRTIELLKELSNWHLLACLTWPLCVTGCMAAPDHEAFFHSLAISAEISPHSLRHTWIVLRILKDVGKVRGSLGEQILPTWEQILCIDGAPILLT
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing (PubMed:30466366).  Both hepR and hepS regulate the transcription of the heptelidic acid cluster, but they are not involved in mutual transcriptional regulation and act with different mechanisms (PubMed:30466366).
What are the official names of this protein?
Transcription factor hepS, Heptelidic acid biosynthesis cluster protein S.
What is the protein family that this protein belongs to?
Belongs to the TRI10 transcription regulator family.
What are the subcellular locations of this protein?
Nucleus.
Protein: M2DH_ASPFC
Sequence: MAPLKLNSRNLSQIAAAGGALVKIPTYQRGRAVKEGIVHIGVGGFHRAHLAVYIDQLMQKHGVNDYAICGVGLQPFDSAMRDALASQDHLYTLIERSAKGSFAHVIGSINSYLFAPDNREAVIAKMAHPDTKIVSLTITESGYYYNENTHELQSEHPDIQFDLDPANEKAPRTTFGFLYAGLTRRYQQGLKPFTVMSCDNMQKNGSITRHMLESFARLRNPEVAEWIAEEGAFPNAMVDRITPQTSETDKTALAEKFGIVDSWPVVTEPFTQWVIEDQFSDGRPPFEKVGVQVVKDVHAVEQFEKHKLRLLNGSHSALGYPGQLAGFQYVHEVMANPLFRKFVWQMMQEEVKPLLPEIPGVDIDEYCNTLIERFTNPTIMDQLPRICLNASGKIPQFIMPSIAEAIWETGPFRRLCFVAAAWFHYIKGVDDRGKPFEVVDPMREELQAKARAGGNDPSELLSIKSLFGDDLRNDERFLREITTAMNDIARDGIMKTLPKYIN
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol 2-dehydrogenase, M2DH, MDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: Y349_CHLPN
Sequence: MDAKMGYIFKVMRWIFCFVACGITFGCTNSGFQNANSRPCILSMNRMIHDCVERVVGNRLATAVLIKGSLDPHAYEMVKGDKDKIAGSAVIFCNGLGLEHTLSLRKHLENNPNSVKLGERLIARGAFVPLEEDGICDPHIWMDLSIWKEAVIEITEVLIEKFPEWSAEFKANSEELVCEMSILDSWAKQCLSTIPENLRYLVSGHNAFSYFTRRYLATPEEVASGAWRSRCISPEGLSPEAQISVRDIMAVVDYINEHDVSVVFPEDTLNQDALKKIVSSLKKSHLVRLAQKPLYSDNVDDNYFSTFKHNVCLITEELGGVALECQR
What is the function of this protein?
Part of an ATP-driven transport system CPn_0346/CPn_0347/CPn_0348/CPn_0349 for a metal.  Metal-binding component.
What are the official names of this protein?
Uncharacterized metal-binding lipoprotein CPn_0349/CP_0411/CPj0349/CpB0356.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CLPX_SHEWM
Sequence: MSDNKSTGDSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPHELRAHLDDYVIGQEKAKKVLSVAVYNHYKRLKNAGPKDGVELGKSNILLIGPTGSGKTLLAETLARFLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDTSKILFVCGGAFSGLEKVIEQRSHTGTGIGFGAQVKGEDDKATISDTLMQVEPEDLVKYGLIPEFIGRLPVLATLAELDDAALIQILSEPKNALTKQFAALFEMEDVELEFREDALKAIALKAKTRKTGARGLRSIVEGILLDIMYDLPSTDNVAKVVIDESVVKGESTPILIYENSESQAASAEQ
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PTFAX_RHOCA
Sequence: MIPLTSELVAIGKTATDKADAIAQAVDLLTAAGKIDPRYGQSMMGREAVANTFLGNGIAIPHGLPQDRDLIHDTAIAVVQLPAGVEWAPGDTARLVVAIAAKSDEHLQVLSNLTDVLGDEAEAERLATTLDAAVIVARLTGAAAPVAAPAETPADFAQGIDVVVTGAHGLHARPATTLVDLAKGFAAEIRIRNGAKVANGKSLISLLNLGAAQGAALRISAEGADATAALAAIAAAFEAGLEDEEDTGAAAPEAATPGLTGAGASMASYEGRTLVGISSSPGYALAPVFRFARDEVVFDTDAADAAFETDRLDTALQTAWHELEELHDEVWKTSGPARAAIFRAHQEFLHDPEMVAEAKALIGQGRSAGFAWHRVFSDRADMLGAMKDAVLSGRAIDLRDAGQRVLQHLGRVRTGETHLPTAPCILLADDLTPSDTARLDPALVRGLATAQGGPTSHTSIIARALDIPAVAGVGPRLLDLATGTPVLLDGGAGVIVVAPTEADKARAETAMAALTAQRELEARERYKPALTVDGARVEVVANISDVAEAIASVEAGAEGVGLLRTEFLFVNREAPPGEDEQLAIYAAMLSALNGLPIIIRTLDVGGDKEIPYLRMPVEQNPFLGERGIRFCLSHEDLFRTQLRAIYRASAGGQVRIMFPMIAMIEELETARRIAEEVRLEVGAAPVEIGIMIEIPSAVMMAPELAKRVDFFSIGTNDLTQYALAMDRMHPVLAKQADGLHPAVLRLIDSTVRAAEAARIWVGACGGIAGDPVGAAVLSGLGVRELSVSIPAVAGIKAQLRHSAMAENRDLARRALACTTAAEVRGLK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FruAB PTS system is involved in fructose transport.
What are the official names of this protein?
Multiphosphoryl transfer protein, MTP, Triphosphoryl transfer protein, TTP.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_CERS4
Sequence: MTEIRLTNTKSRRKEAFEPIDRKNVRLYVCGPTVYDRAHLGNGRPVVVFDVLFRLLRHVYGEGHVTYVRNFTDVDDKINAAALARKDAGDPRSLEALIRERTDETIRWYHEDMDALGALRPTHEPRATEWIGAMIAMIEDLIAKGHAYEREGHVLFRVRSYRDYGALSGRSVDDMIAGARVEVAPFKEDPMDFVLWKPSDDELPGWDSPWGRGRPGWHIECSAMSYELLGATFDIHAGGIDLQFPHHENEIAQSCCAHPEGGFARVWMHNEMLLVDGRKMSKSLGNFFTVRDLLDQGWPGEVIRMVYLGTHYGRPMDWTAEKAEQAKTTLRNWAEMVEGAAPGEVRAEVVDPLSDDLNTAGALAALSDLYKRKDAAGLLGSAHLLGVDLQAIRHQPWARPYAFEELDGRFLREGIDYQPTVGVIGWGEITDQARETSIGLLHRWLALRRAGDFETADRLKTDAMRLGVELRAQKSPNGVTGGLAKLADRVDVSALEGLL
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTF1_SCHPO
Sequence: MAQKKQLYVFSDFDGTITLQDSNDYLTDNFGMGNANRVNLNQQVLDGSISFRDAFAKMLDSVHLSYDEALEVLKKNVAIDPSFKPFYEWCKSQDIRVIILSSGMEPFIRALFEQYLGKEEASSIEIVSNDINVHPDGQWNIVYHDDSHFGHDKSLTIRPYAQLPESKRPHMVYCGDGVSDLSAAKETEHLFAKKGRDLIKYCEREKISFSEFETFADIHKDLQKLFFSS
What is the function of this protein?
May also function as a sugar alcohol (polyol) phosphatase that prevents accumulation of toxic levels of polyol phosphates, which can impair glycolysis by inhibiting glucose-6-phosphate isomerase.
What are the official names of this protein?
Pdp3-interacting factor 1.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CITA_SALTY
Sequence: MAQHTPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGSGFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGRLLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDAISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRIITAGTLLVAMTTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRRAVLMGITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLFVRLSRGYIAAENKA
What is the function of this protein?
Uptake of citrate across the boundary membrane with the concomitant transport of protons into the cell (symport system) (Probable).  Allows the utilization of citrate as a sole source of carbon and energy upon expression in E. coli (PubMed:1718953).
What are the official names of this protein?
Citrate-proton symporter, Citrate carrier protein, Citrate transporter, Citrate utilization determinant, Citrate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPB_SERP5
Sequence: MTDSLIRIAVAGSGGRMGRQLIQAVQQAPGVVLGAAISRPGSSLIGTDAGELAGVGALGVTVSDSLEKVVDDFDILIDFTRPESTLAYLAFCVEHKKAMVIGTTGFDDAGKDAIRAAGQQIGIVFAANFSVGVNLVLKLLEKAAQVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAGALGRDLKECAVYAREGYTGERDPKSIGFATVRAGDIVGEHTAMFADIGERVEITHKASSRMTFASGAVRAASWLHNHDKGLFDMRDVLNLDQL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_CITBB
Sequence: MNAITTIKCPQCRKETTLAGNPYRPFCSQRCKMIDLGTWADEGYRIPGEKAPESGDEEPGDE
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: T2R46_HUMAN
Sequence: MITFLPIIFSILIVVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALAVSRVGLLWVLVLNWYATELNPAFNSIEVRITAYNVWAVINHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVVLVILLGPLLFLVCHLFVINMNQIIWTKEYEGNMTWKIKLRSAMYLSNTTVTILANLVPFTLTLISFLLLICSLCKHLKKMQLHGKGSQDPSMKVHIKALQTVTSFLLLCAIYFLSIIMSVWSFESLENKPVFMFCEAIAFSYPSTHPFILIWGNKKLKQTFLSVLWHVRYWVKGEKPSSS
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).  In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 46, T2R46, Taste receptor type 2 member 54, T2R54.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Protein: RPIA_STRP1
Sequence: MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEGLQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKNFNGIKGGGAALLMEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLEAPTAG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: COAA_ECOL6
Sequence: MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.