PharMolix/UniProtQA huggingface dataset:
Protein: DOHH_DICDI
Sequence: MVVVTEEIVNGLKETLTDVSQPIAKRFRSLFTLRNLNGPLCIDAMASALNDKSALLRHEIAYCLGQMEDEYALKVLIDLVKNSDEHPMVRHEAAEALGAIGSESAHKTLKEYSNDPVREVSETCQLALSRVEWYEKNKPETEEDKMYMSVDPAPPLKKGSVSRDELRSKFLDSNLDIFNRYRALFSLRDIGDEQSVLALCDGLKDQSSALLRHEVAFVLGQLQHRVAIDPLTTCVLDESENAMVRHEAAEALGAIASTETIPLLEKLLQDKEPIVSESCAVALDVTEYFNNTESFQYADGIKILLEKNLVDQQQK
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A.  This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine.  Hypusination is unique to mature eIF-5A factor and is essential for its function.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
Protein: PYRE_PSEPK
Sequence: MQPYQRDFIRFAIDRGVLRFGEFTLKSGRTSPYFFNAGLFNTGSALAELGRCYAAAIVDSKIPFDVLFGPAYKGIPLAATTAVALADQHQLDVPWCFNRKEAKDHGEGGSLVGAPLAGDVLIIDDVITAGTAIREVMQIINAQQAKAAGVLIALNREERGNGELSAIQEVERDFGIPVVSIVSLTQVLEFLADDPQLKQHLPAVEAYRAQYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: DDRA_KLEOK
Sequence: MRYIAGIDIGNSSTEVALATLDEAGALTITHSALAETTGIKGTLRNVFGIQEALALVARGAGIAVSDISLIRINEATPVIGDVAMETITETIITESTMIGHNPKTPGGAGLGTGITITPQELLTRPADAPYILVVSSAFDFADIASVINASLRAGYQITGVILQRDDGVLVSNRLEKPLPIVDEVLYIDRIPLGMLAAIEVAVPGKVIETLSNPYGIATVFNLSPEETKNIVPMARALIGNRSAVVVKTPSGDVKARAIPAGNLELLAQGRSVRVDVAAGAEAIMKAVDGCGRLDNVTGESGTNIGGMLEHVRQTMAELTNKPSSEIFIQDLLAVDTSVPVSVTGGLAGEFSLEQAVGIASMVKSDRLQMAMIAREIEQKLNIDVQIGGAEAEAAILGALTTPGTTRPLAILDLGAGSTDASIINPKGDIIATHLAGAGDMVTMIIARELGLEDRYLAEEIKKYPLAKVESLFHLRHEDGSVQFFSTPLPPAVFARVCVVKADELVPLPGDLALEKVRAIRRSAKERVFVTNALRALRQVSPTGNIRDIPFVVLVGGSSLDFEVPQLVTDALAHYRLVAGRGNIRGSEGPRNAVATGLILSWHKEFAHER
What is the function of this protein?
Large subunit of the diol dehydratase-reactivating factor (DDR), which reactivates suicidally inhibited adenosylcobalamin-dependent diol dehydratase (DD, pddA, pddB, pddC).  DDR acts as a chaperone, reactivating inactivated DD holoenzyme in the presence of ATP, Mg(2+) and free adenosylcobalamin (AdoCbl), by mediating the exchange of the tightly bound damaged cofactor AdoCbl for a free intact one (PubMed:10529189, PubMed:9405397, PubMed:9920879, PubMed:17916188, PubMed:18586770, PubMed:21040475).  Reactivation takes place in two steps: ADP-dependent cobalamin release, then ATP-dependent dissociation of the DD apoenzyme-DDR complex.  DDR has weak ATPase activity which is required for DD reactivation (PubMed:10529189, PubMed:17916188, PubMed:21040475).  This subunit contains the adenosine nucleotide binding site (PubMed:16338403).  Activates glycerol-inactivated, O2-inactivated holoenzyme and inactivated enzyme-cyanocobalamin complex (PubMed:9920879).  Also reactivates glycerol-inactivated hologlycerol dehydratase, a DD isozyme (PubMed:17916188).
What are the official names of this protein?
Diol dehydratase-reactivating factor large subunit, DDR large subunit, Diol dehydratase-reactivase large subunit, Diol dehydratase-reactivating factor alpha subunit, DDR alpha subunit, DDRA.
What is the protein family that this protein belongs to?
Belongs to the DdrA/PduG family.
Protein: DEOD_ECOLI
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (PubMed:235429, PubMed:11786017, PubMed:21672603, PubMed:30337572).  Acts on 6-amino and 6-oxopurines including deoxyinosine, deoxyguanosine, deoxyadenosine, adenosine, guanosine, and inosine (PubMed:235429, PubMed:11786017, PubMed:21672603, PubMed:30337572).  Does not act on xanthosine (Probable).  May also catalyze a phosphate-dependent transfer of the pentose moiety from one purine base to another (PubMed:235429).
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: Y2900_MYCTU
Sequence: MYVEAVRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQQMGALRTAAALARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEEATKRTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRPISWDAAYQLIAEQLNGLDSPDRAVFYTSGRTSNEAAFCYQLLVRSFGTNNLPDCSNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAGQNPGTNHPRMLSVLGKAKANGAKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIADEFVQIRLGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNHCAGFDGYRRRTLQVGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAVATIGEVTNVLLLRGMIGKPGAGVCPVRGHSNVQGDRTMGIWEKMPEQFLAALDREFGITSPRAHGFDTVAAIRAMRDGRVSVFMGMGGNFASATPDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTDRDTRNGRKQLVSVEDSMSMVHLSRGSLHPPSDQVRSEVQIICQLARALFGPGHPVPWERFADDYDTIRDAIAAVVPGCDDYNHKVRVPDGFQLPHPPRDAREFRTSTGKANFAVNPLQWVPVPPGRLVLQTLRSHDQYNTTIYGLDDRYRGVKGGRRVVFINPADIETFGLTAGDRVDLVSEWTDGQGGLQERRAKDFLVVAYSTPVGNAAAYYPETNPLVPLDHTAAQSNTPVSKAIIVRLEPTA
What are the official names of this protein?
Uncharacterized oxidoreductase Rv2900c.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
Protein: APX1_CAEEL
Sequence: MTNFSSLLTTIFLCIISSATGSGTIELLISSPQTVLVEPTVCANFECAAPDDLSLARKVQRRVPLRFGTGQYHGEARERIDLHLKIIEPTSNEILALQHHRPAADTEWNSDAPIVIETSRGFNVTVQLRNLCSSNYHGKRCNRYCIANAKLHWECSTHGVRRCSAGWSGEDCSNPICAGGCSNRGRCVAPNQCSCADGFNGTRCEQCLPRAGCVNGDCVNETPNTCKCRDGFIGDRCDIDIKICSLEKPCANGGICSIDSSSSTGYKCHCPFEFVGSQCKTPLSKVRCSAEHVCKNGGACISMDDTNIQCKCRRGFSGKFCEIGNHGDCSAMRCSAGETCQISGDFAICVENDELLLTTNKPAETTKSVEKWREPRKTANDEQASDELQLRLIAAICVLFSVCVIGLALVSFFFYMHSFSKWKHPSSQQAGGSTILPTTTSIPMSTTSSGTGSPVYKVCIIDSEHRGNAPGSSSDSEPDHHCPPPHRHSPPPAYSSLVLYKKVPMAADDESSFRV
What is the function of this protein?
Probable ligand for lin-12/Notch and glp-1/Notch receptors and involved in the mediation of Notch signaling (PubMed:14960273, PubMed:7568229, PubMed:8575327).  Involved in the lin-12/Notch pathway signaling of cell fate in vulval precursor cells (VPCs), acting redundantly with dsl-1 and lag-2 (PubMed:14960273, PubMed:7568229).  Contributes to the establishment of the dorsal-ventral axis in early embryos (PubMed:8156602, PubMed:18036582).  Involved in the specification of the blastomere cell ABp fate, probably acting as a signal from the P2 blastomere to the glp-1/Notch receptor on ABp and ABa (PubMed:8156602, PubMed:7925031, PubMed:8674418).  Probably acts as a signal, from the secondary vulval epithelial cells and the vulval muscle type 1 (vm1) cells, to activate the lin-12/Notch pathway in type 2 vulval muscle (vm2) cells, contributing to formation of the postsynaptic muscle plasma membrane extensions, known as muscle arms (PubMed:23539368).  Required for oocyte growth control, acting redundantly with lag-2, perhaps signaling via the glp-1/Notch pathway (PubMed:19502484).  Plays a somatic role in ovulation during adulthood, perhaps via lin-12/Notch signaling (PubMed:29371032).  Involved in establishing left-right asymmetry during intestinal organogenesis (PubMed:10903169).
What are the official names of this protein?
Anterior pharynx in excess protein 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm. Note=Nuclear localization of transcripts at 36-cell stage in embryos.
Protein: TX32F_CHIGU
Sequence: MKLCVIIIASLMVASVSGRLRKIKGTELDKKMLLEKLGHGMDIRFEETPRACSKKAGEKCKSNCDCCGYSTLCGYITEGKEVKYQCMSKTSNNKILNTVGLGVNAIENMLSFCFR
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U31-theraphotoxin-Cg1a, U31-TRTX-Cg1a, Jingzhaotoxin-64, JZTX-64.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RR7_CERJA
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LPAA_PORGN
Sequence: AQGDNPDKDTDGN
What is the function of this protein?
Is associated with lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-associated protein.
Protein: 5059R_ASFB7
Sequence: MFSLQDLCRKNLFLPLEPLGKHVVQRLGLYWEGHGSLKRVGDCFICVDKIWILSIHKAIQIAASEGNENIVKLFLLWKGSLQYAIIGALEGRQYDLIQKYYNQIGDCHENLPLIQDPEIYERCHELNVTCTFQCLFQHAIRDNMLPIFQKYGEDLNGNRRMVQLLYEMACRLQNYDIIKWIGFNLHVYNLEAIFSIAFVRKDLTLYSLGYMLLLGRMSTEDRNFISIITRHLEYASKKGLFDFVLESLKYGGQVDTVLFQAVKYNHRKILAHFIHEIPRETVEKLILHAVESRASRKTFNLLLSSINYCVNPFVKKLLHTVVKHKYMLIIKLLLERPKKKINLVDAALFKLVKYSTYAEIVKFMKEFSVDPERVVKMAARLMRVDLIKKISNDAWENKLERIKHLKQMVNTMNHRNGKNLLMYNIHNITGYTCLNTKEAFNLTRFYAVHNATCLFKEMCKSCFVHDKIQFRELLEDCLHIANRHDYIQIAETADECIKYIDLITPK
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-9R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: NIRK_RHIME
Sequence: MSEQFQMTRRSMLAGAAIAGAVTPLIGAVSAHAEEAVAKTAHINVASLPRVKVDLVKPPFVHAHTQKAEGGPKVVEFTLTIEEKKIVIDEQGTELHAMTFNGSVPGPLMVVHQDDYVELTLINPDTNTLQHNIDFHSATGALGGGALTVVNPGDTTVLRFKASKAGVFVYHCAPPGMVPWHVTSGMNGAIMVLPREGLTDGKGNSITYDKVYYVGEQDFYVPRDANGKFKKYESVGEAYADTLEVMRTLTPSHIVFNGAVGALTGDSALKAAVGEKVLIVHSQANRDTRPHLIGGHGDYVWATGKFRNAPDVDQETWFIPGGTAGAAFYTFEQPGIYAYVNHNLIEAFELGAAAHFAVTGDWNDDLMTSVRAPSGT
What are the official names of this protein?
Copper-containing nitrite reductase, Cu-NIR.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y875_METJA
Sequence: MDSNILNIRELRKQAVNLEKEAKKEKQNGNYKKSAELFLKASEIYNKIRDEKNKKWTLANYYSIMAKEYSFSNEFDKAREFYKKAEELFLELGIKKSAMYCFYYYLKTYIYEEKEKVEKKDNDKYLELLNKYIIEAEQFLEKYKEFSDIWMYFDIKIYYYKKLSIKHRKFEGNLDKAIELTEKCYKLAEESYNKFNDKNYKKAEIFNKHFYYNLMAQKFESERKFKEAAEYYKKSGDTIKEIDEKIAYDEYANSYKWLAIENKYNKEKFEEYINKAIEFSEKRGDKLQEYYYLGLKYDHLVRFANDLEEKIDYIKKSKEYYYRSKSFEFAKYMEYLEYYYQFKYELLNGNYEKALNFLQKAKKSLKNVKISNIIFSKYTLECDELICRFYLSISQGEFKKSVELLDEYLEISLKILSDWKNTRKYKFYEYLKPCVEILSKESFTKDDLFLLEDVILEVRNEKISLNLYKICSLTYAYVSLWKNKIRDKEILEKIKLKIIKQITTEDVSKDLENRIKIQMAIERNDWLLRLPPALVENFDNCIYFLEEVLDEFKHAAYREFYRLLENYLKIIVEFNAMALWGDTWKQILEEKISNRKKPFEIFTFGDFAQSLRLLKNEGCEYCKNIDDEIFDLLDKHVKIRNNLSHDFNAKAPEDIDIKGDTLKIIYSTLNAFPICVKVTHDKKKPWYGVEVIWNQLPKKMSLYSNTELKKGCLYYIEPYSNILDKNKMHPKIIIPIEVSKDIVYPNKN
What are the official names of this protein?
Uncharacterized protein MJ0875.
Protein: ULAD_SALPK
Sequence: MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAESPVEAARQFKRSIAQLWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: Y1653_NEIMB
Sequence: MNNSVITVIGKDRVGIVYDVSKILAENQINILNISQQLMDDFFTMIILVDTSKCSKSRQEVLDLFAEESKKLALDIRMQNEEIFQAMHRI
What are the official names of this protein?
UPF0237 protein NMB1653.
What is the protein family that this protein belongs to?
Belongs to the UPF0237 family.
Protein: MOAC_CERS4
Sequence: MSGLTHFDESGRAHMVDVSEKPVTARVAVARGAVKMSAETLALVTEGRAEKGDVLGVARLAGIMGAKRTADLIPLCHPLPITKVALELTADPALPGVVVEATVKTGGQTGVEMEALTAVSVACLTIYDMVKAVEKGMEITGIRLLLKEGGKSGRFEASA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: C77A2_SOLME
Sequence: MDFFSTSSLSSYYHLIFTILAFVISSIIYFLSKKAESKKLKLPPGPPGWPVVGNLLQVARSGKPFFQIMRELRQKYGPIFTLRMGTRTMIILSNADLVHEALILKGQVFATRPRENPTRTVFSCDKFTVNAAVYGPVWRSLRKNMVQNGLSSIRLKEFRAVRKSAMDKMIEKIRAEADANEGVVWVLKNARFAVFCILLAMCFGVEMDEKTIEKIDQMMKSVLIALDPRLDDYLPILSPFFSKQRKHAMDVRKQQIKTIVPFIEQRKKILESPEIDKTAASFSYLDTLFDLKIEGRNSTPTYPELVTLCSEFLNGGTDTTATAIEWAIGRLIENPNIQSQLYEEIKKTVGENKIDEKDIEKMPYLNAVVKELLRKHPPTYMSLTHAVTEPAKLGGYDIPTGVNVEIFLPGISDDPNLWSEPEKFDPDRFYLGKEDADITGVSGVKMIPFGMGRRICPGLNMATVHVSLMLARLVQEFEWADPENTRVDFTEKLEFTVVMKNTLRAKIKPRM
What are the official names of this protein?
Cytochrome P450 77A2, CYPLXXVIIA2, Cytochrome P-450EG5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: FOLCP_HALSA
Sequence: MRYDEAANFLLDLRRYGPKPGTESTADLLASLGDPHQDGPDYVQIAGSNGKGSTARFTESILRAAGLDVGLYTSPHFDDVRERVTVNGRRMSKAALTTFIETITPYVTERAADGAAPTYFEVVTAMALWQFSRADVDVAVLEVGIGGRLDATSVVDPSASAVTSVTLEHTDVLGETIPEIARDKAHVAPAGDTPLVTATTDDALAAVRDHAGAVRTVGDTAGRDVTATYEGRTNHTEAAVSITGDDWSVATEIPLLGDHQAENAGVAAALARQTAGVDDDAIARGLRSAHWPGRFEVMGADPVVVLDGAHNPGACGAVAETVAEFDYDRLLTVFGAMHDKDHGAMAAALPTPDHVWACEPVPDRAEDADVLAAVFEDAGAGTVSVTRAVESAVADAIAEATADDLVLVAGSLFAVAEARTRWTRTFAETDVDSLDDARDALERAHVTPPGVWRMRGKGVHRVVKTRVQTRQAQYLKEELLSLGGECSVSGLNAQSGAMVDAVMMATMAQFKRLCEKLDGQPYGLSEVGADLRESLGIQAAPATHGYPWEGERTAVMGILNVTPDSFHDGGEYDALEDAVARAESMAENGVDVIDIGGESTRPGADAVSVADELDRVLPVIERISDLDVLLSVDTRKAEVARQALEAGADILNDVTGLDDPEMRFVAAEYDAPIVVMHSIDAPVDPDSDPDYDDVVDDVIAELTERVLLAEKAGVPRERIIVDPGLGFGKSAAEGFELLDRADEFHALGGPVLVGHSHKSMFGAVDRYPDEGGYATAAASALAADRGADIVRVHDVPENVAAVRVAEATRTGADAE
What is the function of this protein?
Can complement an H. volcanii mutant strain that is thymidine auxotroph because it lacks the two dihydrofolate reductase genes encoded by hdrA and hdrB.
What are the official names of this protein?
Probable bifunctional folylpolyglutamate synthase/dihydropteroate synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DHPS family.
Protein: ATPA_TUPAK
Sequence: MVKIQPDEISSIIRQQIAQYSEEVKVVNVGTVFQVGDGIARIYGLEKVMAGELLEFEDGTIGIALNLETKNVGAVLMGDGLAIQEGSSVRATGKIAQIPVSESYLGRVVNSLALPIDGKGAINSSETRLIESLAPGIISRRSVHEPLQTGLVAVDAMIPIGRGQRELIIGDRQTGKTAIAVDTIINQKGKDVICVYVAIGQKASSIAQVVNSLEERGCLSYTIIVAATADTPATLQYLAPYTGATLAEYFMYKGRHTLVIYDDLSKQAQAYREMSLLLRRPPGREAFPGDVFYLHSRLLERAAKLSDQLGGGSMTALPIVETQEGDVSAYIPTNVISITDGQIFLSGDIFNSGIRPAINVGISVSRVGSAAQPKAMKKVAGKLKLELAQFAELEAFSQFASDLDQATQKQLSRGSRLRELLKQAQSSPLALEDQVSTIYAGINGYLDGIPVENVRAFLVELRQYLASSKPKYGQILRDTEAFTEEAESILKEALVELTGSKN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PPT1_RAT
Sequence: MASPGYRRLLAAALLPWCCAAWALGHLDPPSPPPLVIWHGMGDSCCNPMSMGSIKKMVEKEIPGIYVLSLEIGKNMVEDVENSFFLNVNLQVGMACQILEKDPKLQHGYNAIGFSQGGQFLRAVAQRCPTPPMMTLISVGGQHQGVFGLPRCPGESSHICDFIRKSLNAGAYSKVVQERLVQAQYWHDPIKEEVYRNCSIFLADINQERHINESYKENLMALKKFVMVKFFNDSIVDPVDSEWFGFYRSGQAKETIPLQETTLYTEDRLGLKKMDKAGKLVFLAKEGDHLQISKEWFTAHIIPFLK
What is the function of this protein?
Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation.  Prefers acyl chain lengths of 14 to 18 carbons.
What are the official names of this protein?
Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the palmitoyl-protein thioesterase family.
What are the subcellular locations of this protein?
Lysosome. Secreted.
Protein: CYSJ_NEIMA
Sequence: MSEHDMQNTNPPLPPMPPEITQLLSGLDAAQWAWLSGYAWAKAGNGASAGLPALQTALPTAEPFSVTVLSASQTGNAKSVADKAADSLEAAGIQVSRAELKDYKAKNIAGERRLLLVTSTQGEGEPPEEAVVLHKLLNGKKAPKLDKLQFAVLGLGDSSYPNFCRAGKDFDKRFEELGAKRLLERVDADLDFAAAADGWTDNIAALLKEEAAKNRATPAPQTTPPAGLQTAPDGRYCKADPFPAALLANQKITARQSDKDVRHIEIDLSGSDLHYLPGDALGVWFDNDPALVREILDLLGIDQATEIQAGGKTLPVASALLSHFELTQNTPAFVKGYAPFADDDELDRIAADNAVLQGFVQSTPIADVLHRFPAKLTAEQFAGLLRPLAPRLYSISSSQAEVGDEVHLTVGAVRFEHEGRARAGGASGFLADRLEEDGTVRVFVERNDGFRLPEDSRKPIVMIGSGTGVAPFRAFVQQRAAENAEGKNWLFFGNPHFARDFLYQTEWQQFAKDGFLHRYDFAWSRDQEEKIYVQDKIREQAEGLWQWLQEGAHIYVCGDAAKMAKDVEAALLDVIIGAGHLDEEGAEEYLDMLREEKRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: DRL41_ARATH
Sequence: MNSNSIQSFDALPHNLRECFLDMASFLEDQRIIASTIIDLWSASYGKEGMNNLQDLASRNLLKLLPIGRNEYEDGFYNELLVKQDNVLREFAINQCLKESSSIFERKRLNLEIQDNKFPNWCLNPKQPIVINASLFSISTDDSFASSWFEMDCPNVEALVLNISSSNYALPNFIATMKELKVVIIINHGLEPAKLTNLSCLSSLPNLKRIRFEKVSISLLDIPKLGLKSLEKLSLWFCHVVDALNELEDVSETLQSLQEIEIDYCYNLDELPYWISQVVSLKKLSVTNCNKLCRVIEAIGDLRDLETLRLSSCASLLELPETIDRLDNLRFLDVSGGFQLKNLPLEIGKLKKLEKISMKDCYRCELPDSVKNLENLEVKCDEDTAFLWKILKPEMKNLTITEEKTEHNLNLLQLF
What is the function of this protein?
Possible disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein At5g66890.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: RNPA_SALAR
Sequence: MVKLAFPRELRLLTPAHFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRQRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CH60_CLOAB
Sequence: MAKQILYGEEARRSMQKGVDKLADTVKVTLGPKGRNVVLDKKFGAPLITNDGVSIAKEIELEDPYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLKNVTAGANPMLIRNGIRLAVDKTVEGLKKVSKNVNGKEDIARVASISAADPEIGKLIADAMEKVGNEGVITVEESKSMGTELDVVEGMQFDRGYLSPYMVTDQEKMEAVLDDPYILITDKKIANIQEILPLLEQIVQQGKKLLIIADDVEGEALATLVVNKLRGTFNCVAVKAPGFGDRRKDMLRDIAILTGGEVISEELGKDLKDVKVEDLGSAESVKISKENTTIVNGRGDKSAIHDRVAQIRGQIEETTSDFDREKLQERLAKLAGGVAVVKVGAASETELKERKMRIEDALAATKAAVEEGIIAGGGTAYINVLPEVRELTSDEPDVQVGINIIVKALEEPVRQIAANAGLEGSVIIEKIINSEKGIGFDALHEKYVDMLSVGIVDPTKVTRSALQNAASVASTFLTTECAVADIPEKDKPEMPGGAPGMGMGGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUHM_BPSP1
Sequence: MYTFSGSKPTQLYMDILSTVIKEGDVLAPRGKRIKEIRPVMIEFKNPIRRTTFLKGRNINPFFQVAESLWILAGRSDVGFLLDYNKNMGQFSDDGVFFNAPYGERLRFWNRSDANNFIYNPLDQLRDVYEKIKADPDTRQAVAVIYNPLFDNINNDTKDRPCNLLLSFKLRNGKLDLSVYNRSNDLHWGTFGANLCQFSTILEAMATWLGVEVGSYYQITDSLHVYLDDYGAKITEDIQKVYGVNLETDEAPVVEDFEELLDPNPRMSYTMNELNQFLNEYFGIVDSLMRDDETYMHDGDCAQMLLNQIRHEPDEYIKVTLLLMVAKQALNRGMKDTVATAMNWIPLCEIKVSALRFLYKSYPEYINQYDLDEKLMKYIRREE
What is the function of this protein?
Catalyzes formation of 5-hydroxymethyldeoxyuridylate (5HMdUMP) as a step in the pathway that replaces dTMP by thymidine hypermodifications in the viral genome (PubMed:8527927).  As a final result of the pathway of hypermodification, hydroxymethyluracil substitutes for a subset of thymidines in the viral DNA (PubMed:8527927).  These modifications probably prevent degradation of viral DNA by the host restriction-modification antiviral defense system (PubMed:8527927, PubMed:21597187).
What are the official names of this protein?
Deoxyuridylate hydroxymethyltransferase, Deoxyuridylate hydroxymethylase, Gp29, dUMP hydroxymethylase, dUMP-HMase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: RAD5_CANAL
Sequence: MKVIKKRFFKPKEETLPSDEVPDPQSSAEPLHSLFVPDESEEEETTTSPKTNFEKDIIAIVGDISPIIMKYLYAKYSQKRNGAKFAVTELLTNPPDVEKLQQDSIASQSAKRPHTIVSYQEPPNKKVNINPDSASSNNEPLMWQRLIGSLNIQAMATXPDHETVEIPGKXKLKRITTKNSTMANSAIVRVYHNEREIGRIPEDWTRILSPLFDLNIAVFEASVLEETKSRLSTGDSFVIEIEVYLTNSSFAKNLDATENPIDLKKSNFDYSKESESEAALRLRQFAISNLFDRLAIKPLKVNDDTEDEEDISSQEINSGDVEHPVPEINLDQMKEFYQSNNQLKILEGLPETTTPPKENFALDLRSYQKHGLSWMLAREKELDVLEMLSNEDKLSSQSRKELENLGTMNPLWRKYKWPYATEATQDPTQNQTEKYFYANMYNGELSLEKPVIKSSLRGGILADEMGLGKTIATLALVNSVPYDNFPEPKSDRPYASQTTLIVVPMSLLFQWKSEFEKCNNNSRHVCRLHYGEDQETNLAWSLCNPDNSKIPIVMITTYGTVLNEFTRLSKRRNSKGELPKVGLYSVKFFRIILDEGHNIRNRNTKTAKSVYELQSSRKWILTGTPIVNRLDDLYSLTKFLELDPWNNFSYWKTFVTLPFEQKKISQTLDVVKSILEPIFLRRTKSQKKNGKPLVELPAKEVVIEQIKFNDDEEKLYQWFKDRAYASFAEGIKSGQLLRRYTQILTHILRLRQVCCHVDLIGGAHEMDDEIIEAEQDEDMRKFLTSIKENQIRFANDTDVKEKMYNLYGKIKEENECSICTQVPIPYSEMVVTPCAHTFCLSCILEHLDFQKELKKEKLCPNCRSPISKYQLFRIRNQPTKGNEIRFHIQKDAPDYSFQLYLYDPNRSSSKIQALVRHLKALHSQSPNSKVIVFSQFSSYLDIIQSELKLASEEFIVFKFDGRLNMNDRTKLLESFNQPLEDGKVAILLLSLKAGGVGLNLTTASRAYMMDPWWSPSIEDQAIDRIHRIGQNETVKVVRFIMENSIETKMLKIQERKKQIGEAVAAEEEERRKRRIEEIQILFEE
What is the function of this protein?
Probable helicase, member of the UBC2/RAD6 epistasis group.  Functions with DNA repair protein RAD18 in error-free postreplication DNA repair.  Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats.  Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).
What are the official names of this protein?
DNA repair protein RAD5.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.