PharMolix/UniProtQA huggingface dataset:
Protein: L6_LINUS
Sequence: MSYLREVATAVALLLPFILLNKFWRPNSKDSIVNDDDDSTSEVDAISDSTNPSGSFPSVEYEVFLSFRGPDTREQFTDFLYQSLRRYKIHTFRDDDELLKGKEIGPNLLRAIDQSKIYVPIISSGYADSKWCLMELAEIVRRQEEDPRRIILPIFYMVDPSDVRHQTGCYKKAFRKHANKFDGQTIQNWKDALKKVGDLKGWHIGKNDKQGAIADKVSADIWSHISKENLILETDELVGIDDHITAVLEKLSLDSENVTMVGLYGMGGIGKTTTAKAVYNKISSCFDCCCFIDNIRETQEKDGVVVLQKKLVSEILRIDSGSVGFNNDSGGRKTIKERVSRFKILVVLDDVDEKFKFEDMLGSPKDFISQSRFIITSRSMRVLGTLNENQCKLYEVGSMSKPRSLELFSKHAFKKNTPPSYYETLANDVVDTTAGLPLTLKVIGSLLFKQEIAVWEDTLEQLRRTLNLDEVYDRLKISYDALNPEAKEIFLDIACFFIGQNKEEPYYMWTDCNFYPASNIIFLIQRCMIQVGDDDEFKMHDQLRDMGREIVRREDVLPWKRSRIWSAEEGIDLLLNKKGSSKVKAISIPWGVKYEFKSECFLNLSELRYLHAREAMLTGDFNNLLPNLKWLELPFYKHGEDDPPLTNYTMKNLIIVILEHSHITADDWGGWRHMMKMAERLKVVRLASNYSLYGRRVRLSDCWRFPKSIEVLSMTAIEMDEVDIGELKKLKTLVLKFCPIQKISGGTFGMLKGLRELCLEFNWGTNLREVVADIGQLSSLKVLKTTGAKEVEINEFPLGLKELSTSSRIPNLSQLLDLEVLKVYDCKDGFDMPPASPSEDESSVWWKVSKLKSLQLEKTRINVNVVDDASSGGHLPRYLLPTSLTYLKIYQCTEPTWLPGIENLENLTSLEVNDIFQTLGGDLDGLQGLRSLEILRIRKVNGLARIKGLKDLLCSSTCKLRKFYITECPDLIELLPCELGGQTVVVPSMAELTIRDCPRLEVGPMIRSLPKFPMLKKLDLAVANITKEEDLDAIGSLEELVSLELELDDTSSGIERIVSSSKLQKLTTLVVKVPSLREIEGLEELKSLQDLYLEGCTSLGRLPLEKLKELDIGGCPDLTELVQTVVAVPSLRGLTIRDCPRLEVGPMIQSLPKFPMLNELTLSMVNITKEDELEVLGSLEELDSLELTLDDTCSSIERISFLSKLQKLTTLIVEVPSLREIEGLAELKSLRILYLEGCTSLERLWPDQQQLGSLKNLNVLDIQGCKSLSVDHLSALKTTLPPRARITWPDQPYR
What is the function of this protein?
TIR-NB-LRR receptor-like protein that confers resistance to the flax rust phytopathogenic fungus (M. lini) (PubMed:7549479).  An NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792).  Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (PubMed:31439792).  Makes small amounts of 2' cyclic ADPR (2'cADPR) (PubMed:36048923).
What are the official names of this protein?
Disease resistance protein L6, 2' cyclic ADP-D-ribose synthase, 2'cADPR synthase L6, NAD(+) hydrolase L6, NADP(+) hydrolase L6.
What is the protein family that this protein belongs to?
Belongs to the disease resistance TIR-NB-LRR family.
Protein: LEP4_DICNO
Sequence: MLISELLQTPLGIFFVGLFSLMVGSFLNVVIYRVPVMMDREEKQYAWQVFHGEDSVCPEIPKQRFNLLVPASRCPHCGHRIRAIENIPVISWLFLKGKCSGCGAAISARYLLVELLTAALSVIVAFHYHDPLSLGFALVFTWTLIALCFIDAEHQLLPDRLTLPLLWLGILAALFNVFINLESSVIGAMIGYLSLWSVYWLFKLITGREGMGYGDFKLLACLCAWQGAWMLPIILFSAAILGMIYALGIGLRMGKPMPFGPFLAIAGWLTFLYGAQIGQLFGYFPA
What is the function of this protein?
Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.
What are the official names of this protein?
Prepilin leader peptidase/N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDRP_LACJO
Sequence: MTEEKKENQKIVNLIIISDSVGDTAFNMVQAGAVQYPNVKFNYRRYPFITNREKLEKVFSEITEFENVLIAFTLIHEDEQLAVIKFAREHNMKYVDLLSGVIDNIHALTGEEPKHEIGAVHHMGQNYFDRISAMEFAVMYDDGKDPKGFLEADVVLLGVSRTSKTPLSLFLANKNLKVANLPLVPQTHIPDEIYKINPKKIIGLTNDPSVLNEIRRQRMIAYGLNPDTTYSNMDSINAELEAADKLYKKLGCYVINVAHRSIEETAALILEHLGIDDYAK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: HIS7_STAS1
Sequence: MIFQKKRKTAETELSIILADDKRTSEINTGVGFLNHMLTLFTFHSGLSIIIEANGDTEVDDHHVTEDIGIVLGQLLLDMIRERKSFQRYGVSYIPMDETLSRAVVDISGRPYLSFNATLSKEKVGTFDSELVEEFFRALIINARLTTHIDLLRGGNTHHEIEAIFKSFARALKMALSENDNDNIPSSKGVIE
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODP1_MYCS2
Sequence: MTTEFVRQDLAQNSSTAAEPDRVRVIREGVASYLPDIDTEETAEWLESFDELLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGFNHFFRGKSHPGGGDHVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHSGGGLPSYPHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEPESRGLIQVAANEALDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWDVLLHADRDGALVNLMNSTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVADMSDQEIWNLKRGGHDYRKVYAAYRAAMEHKGQPTVILAKTIKGYTLGQHFEGRNATHQMKKLALEDLKNFRDVTRVPVSDAQLEEDPYLPPYYHPGPEAPEIRYLLERRRALGGFVPSRRTKSKPLALPGSDTYKALKKGSGSQAVATTMATVRTFKELLRDKNIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTSVDSELMLAYKESEVGQILHEGINEAGSTSSFTAVGTSYSTHDEPMIPIYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAAVTYDPAFAYEIAHIIESGLQRMYGEDPENVFFYLTIYNEPYQQPAEPENLDVEALLKGLYLYRPAPEKRAKSAQILASGVAMPEALRAADLLASDWDVAADVWSVTSWGELNREGVAIEKHRLRHPDEPAGTPHVTSALADAAGPVIAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSDTRPAARRYFNTDAESVVVAVLQGLARDGEIDASVAAQAAEQYRIDDVSAAGVSYADTGSA
What is the function of this protein?
Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component, PDH E1 component.
Protein: YXZE_BACSU
Sequence: MIVIILLFISIIVFLSVIQPQPSKNKSRQQADSGYFGYSDHSSHHDGCSSDGGFSDSGCGGGGGGD
What are the official names of this protein?
Uncharacterized protein YxzE.
Protein: LOLA_ALIFM
Sequence: MKKFLFSLCLLSSTVLASPQSELTERLNQNAGFEAGFTQKVLSPEGDVLMQGEGDVKILRPNLFRWHTQTPDENLLVTDGNTLWYYNPFVEQVTLMGLEKATTQTPFVLLTRNKASDWDNYSVSQNGDAFTVSPKADSAVKSEFIVRIQENGKVTGFSVVEQDGQRSDFDFTKFEAKKPAKNNFTFAIPDGVDIDDQR
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYI_BACC0
Sequence: MEYKNTLLMPKTEFPMRGNLPKREPAMQEKWAEMNIYEKVQEHTKGRPLFVLHDGPPYANGDIHMGHALNKVLKDFIVRYKSMTGFCAPYVPGWDTHGLPIEQALTNKGVKRKEMTVAEFRKLCAEYAYEQVERQREQFKRLGVRADWDNPYITLEPAYEAQQIKVFGDMAKKGYIYKGQKPVYWSPTSESALAEAEIEYQDKKSASIYVAFPVKDGKNVLEGDEKYIIWTTTPWTLPANLGISVHPELEYAIVKVNDEKYIIASELFETVAKTLEWENAEVVKTVKGSELEYTVAKHPFYDRDSLVMLGDHVTTDAGTGCVHTAPGHGEDDFIVGKKYGLEVLCPVDDKGVLTEEAPGFEGLFYDKANKPITEKLEEVGALLKLTFITHSYPHDWRTKKPIIFRATAQWFASIEAFRKELLEAVAETKWVPAWGETRLHNMVRDRGDWCISRQRAWGVPIPVFYAENGDPIITDETINHVADLFREHGSNVWFEREAKDLLPEGFTHPGSPNGEFRKETDIMDVWFDSGSSHQAVLEERDDLQRPADLYLEGSDQYRGWFNSSLSTAVAVTGKAPYKGVLSHGFVLDGEGRKMSKSIGNIVVPKKIMDQLGGDILRLWVSSVDYQSDVRISDDILKQVAEVYRKIRNTFRFLLGNLDDFKPSENTVAVAELREVDRYMLVKLNDLITKVKEAYETYDFAAVYHAIHNFCTIDLSSFYLDFAKDILYIEGANHEDRRAIQTVLYDVLVALTKLVTPILPHTADEVWPYIPGVTEESVQLTDMPEAVQLDDAEALKTKWDAFMTLRDDVLKALEVARNEKVIGKSLNASITLYPTAEMKAMLESINEDLKQLFIVSEYKLGGMMEEAPADAPKYEHTAVVVAQATGETCERCWVVSETIGKDAEHETLCERCATVVKENYVK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y479_STRP6
Sequence: MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYSLYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLFKIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKANDTATMISYWPLTISEELALMIEGYFYKLDKNELPTPRFTKMGGDIKVMVVRNDLEYSIRINFPLISKFFNNDIESQLYVDKHVEKIKKYIEQKYKNISFSIDYHYYLTTTGSCIDFGEEGAVGRGNKTHGIISSFRPNTMEAPAGKNCTYFVGKVWGFLSDTIAKEIYEAFNTPCQIIMQLNIGSKLYRPTHLFIQTEESVDQERVLEIVNRHLNNGKQNTNLILSTQHFIPKTNVYDG
What are the official names of this protein?
Uncharacterized protein M6_Spy0479.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthetase 2 family.
Protein: CITG_STRP1
Sequence: MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFITFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKGLNFSMALLLGATGAYLARTPHLMTDLGRFSKEDTLAICRLVKPMTAHLIQTDLGHLNTKKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYLMSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGGAADLLALTFYFAFLEKLL
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: RPOB_SHEVI
Sequence: MVYSYSEKKRIRKDFGKRPKVLDIPYLLSIQLDSFKKFTDQDPTGERGFEAAFRSVFPIKSFSGNSELQYVSYKLGEPVFDVKECQIRGITYAAPLRVKLRMVLYDREAAPGTVKDIKEQEVYMGDIPLMTNNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLPASIMLRALDYSTQDILDLFFDRVNFKIKKDSLVMDLVPERLRGETASYDIKDSDGSILVEKGRRVTARHIRQLEKSKTTELEVPVDYIEGKIAGQDYIDPDTGEVLVSANAEITLEDLAKLSMAGIKEISTLYINDLDNGAYMSDTLRIDSTTNRLEALVEIYRMMRPGEPPTKDAAEGLFQNLFFSEERYDLSKVGRMKFNRRLSIGEDEGSGILSKEDIVAVMKNIITIRNGGDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLASFARTNSYGFLETPYRKVEDGVVTDQIDYLSAIEEGRYVIAQANIDIDKNGRLLEEQVACRHKGDSTFMRGTDIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGIERIIAVDSGVVVVAKRGGSIDYVDASRIVVKVNESELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGDPVVVGDVLADGPSTDLGDLAFGQNMRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAVEIEEMHIAQAKKDLTEEFKILEEGVYGRARNLLLNAGFEQAQLDAIPRSHLLVQTIDDEAKQTELEQLAEQHDELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKINPVEDMPYDENGNPIDIVLNPLGVPSRMNIGQILEVHMGAAAKGIGDQITAMLEEQRQLAEIRGYIKEVYELGDEVLQRVDIDSFTDDEVLRLAKNLKGGIPIATPAFDGAKEKEIKEMLALAKLPTSGQRTLYDGRTGNEFERKVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNYQMQPGMPESFNVLLKEIRSLGINIELDQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: NMU_HUMAN
Sequence: MLRTESCRPRSPAGQVAAASPLLLLLLLLAWCAGACRGAPILPQGLQPEQQLQLWNEIDDTCSSFLSIDSQPQASNALEELCFMIMGMLPKPQEQDEKDNTKRFLFHYSKTQKLGKSNVVSSVVHPLLQLVPHLHERRMKRFRVDEEFQSPFASQSRGYFLFRPRNGRRSAGFI
What is the function of this protein?
Does not function as a ligand for either NMUR1 or NMUR2.  Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system.
What are the official names of this protein?
Neuromedin-U.
What is the protein family that this protein belongs to?
Belongs to the NmU family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y5073_PSEF5
Sequence: MLQGSSQHSGRDAESQALRHLQQHGLRLLAQNWLCKRGELDLVMLDGDTVVFVEVRYRKHTQWGGALGSIDGRKRQKLILAAQLFLQSESRWSSHPCRFDVVAIDGASGAEARLNWLRNAFDS
What are the official names of this protein?
UPF0102 protein PFL_5073.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: SYE2_BRUC2
Sequence: MSKPVITRFAPSPTGYLHIGGARTALFNWLYAKHCGGKMLLRIEDTDRERSTEAATAAILDGLTWLGLDWDGEAISQFERAPRHREVAEELVANGKAYYCYASPEELEEMREKARAEGRPPRYDGRWRDRDPSEAPAGVKPVIRIKAPRDGETVVHDAVQGDVRFPNKDLDDFIILRSDGTPTYMHAVVVDDHDMGVTHIIRGDDHLTNAARQTIIYNAMGWDVPQMSHIPLIHGADGAKLSKRHGALGVDAYRAMGYLPAALRNYLVRLGWSHGDDEIMSTEQMIEWFDVKDINKGAARFDFQKLEAINGLYMRSSDDQALFDALVAVLPEIEGGKELAEALDDKGRAQLLLAMPGLKERAKTLVELADGAKFIFASRPLALDEKAASLLNDEGRAVLKPVYPVLEAVGEWTAESLDAAIRAHAEAEGLKLGKIAQPLRAALTGRATSPGVFDVLVVLGREESLARIGDQIG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEAD4_MOUSE
Sequence: MTSNEWSSPDSPEGSSISGGSQALDKPIDNDAEGVWSPEIERSFQEALAIYPPCGRRKIILTEEGKMYGRNELIARHIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKDQAAKNKALQSMAAMSSAQIVSATAFHSKMALARGPGYPAISGFWQGALPGQPGTSHDVKPFSQNTYPVQPPLPLPGFESPAGPTPSPSAPLAPPWQGRSIASSKLWMLEFSAFLERQQDPDTYNKHLFVHISQSSPSYSDPYLETVDIRQIYDKFPEKKGGLKELFERGPSNAFFLVKFWADLNTNIDDEGSAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE
What is the function of this protein?
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction.  Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription.  Binds to the M-CAT motif (By similarity).  Might play a role in the embryonic development of skeletal muscle.
What are the official names of this protein?
Transcriptional enhancer factor TEF-3, ETF-related factor 2, ETFR-2, TEA domain family member 4, TEAD-4, TEF-1-related factor 1, TEF-1-related factor FR-19, RTEF-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: INA17_YEAST
Sequence: MLKRRSNALITLSRTKLFPITTVAYYHRRLLNQQRRAVSTSPKKEIKSLEDLANLDSLDGVDTELIRDLINEHTTKLNIKKELDMLKKFSQEEESGHEIPVKRFIRPLWMFILMGSSVYLLLHFSWWKLEHEERESQLKKEVEILEHQLNELIVQDKTHNTSRGKGSNESTHMKPWYRRWFW
What is the function of this protein?
Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase.  INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain.
What are the official names of this protein?
Inner membrane assembly complex subunit 17, Altered inheritance of mitochondria protein 43, Found in mitochondrial proteome protein 14, INA complex 17 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the INA17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NOX_THET8
Sequence: MEATLPVLDAKTAALKRRSIRRYRKDPVPEGLLREILEAALRAPSAWNLQPWRIVVVRDPATKRALREAAFGQAHVEEAPVVLVLYADLEDALAHLDEVIHPGVQGERREAQKQAIQRAFAAMGQEARKAWASGQSYILLGYLLLLLEAYGLGSVPMLGFDPERVRAILGLPSHAAIPALVALGYPAEEGYPSHRLPLERVVLWR
What is the function of this protein?
Can oxidize either NADH or NADPH with a preference for NADH.  Can catalyze electron transfer from NADH to various electron acceptors which include, in addition to molecular oxygen, cytochrome c, 2,6 dichlorphenolindophenol, methylene blue, ferricyanide or P-nitroblue tetrazolium.
What are the official names of this protein?
NADH dehydrogenase, H(2)O(2)-forming NADH oxidase, NADH:oxygen oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: RNH2_SERP5
Sequence: MIEPFIYPVATLIAGVDEVGRGPLVGAVVTAAVILDPARPIVGLADSKKLSEKRRLALYDEIVEKALSWSLGRAEPDEIDQLNILHATMLAMQRAVAGLHIAPDMVLIDGNRCPKLPMRSQAVVKGDSRVAEISAASILAKVTRDREMTELDREFPDYGFAQHKGYPTAFHLERLAALGATEHHRRSFAPVRRVLAL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_RHOPS
Sequence: MLNSLDLEGRPQDTRVVVAMSGGVDSSATAALLKSQGYDVVGITLQLYDHGAATHRKGACCAGQDIHDARAVAERIGIPHYVLDYESRFRESVIDSFADSYALGETPVPCIECNRSVKFRDLLATARELGASALATGHYVSSRRLDDGSRALICAADRDRDQSYFLFATTREQLDFLRFPLGDMTKPQTRELARQFGLSVADKHDSQDICFVPTGRYTDVVERLKPNAMEPGEIVDLNGHVLGSHPGIVHFTVGQRRGLGIASRAPLYVLRLDAAHRRVVVGPREALRMERIVLRDVNWIGDGAIDQAVGDGLELFVRVRSTRAPQPAWLRAVGGGYEVELVAGEEGVSPGQACVFYDAADGQARVLGGGFIKSAAPRWSADGVRDDAASPALAAMRG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL033_MIMIV
Sequence: MSKKISRSIDTIIFVDINSRYTKCQYCDIYIIIDNENGYINITSLCSIISKKIGKEKTFKQWKKNKTSKEQVEEMAKLEKISEKKLFIDICSGPKKMQGKYIHPGLVTLVVHWISPEFAAKVSLWIEEWRRYSSNNSDKYYESLLTANPSYNSQREKEIQEKLLGKYGGEIEVETKTGRIDLMTNDKIIEIKNYYKWKNAIGQLFAYSIYYPDKKKCLYLFNVGTNDLNEIKKVCKKYDVKLKVYD
What are the official names of this protein?
Putative KilA-N domain-containing protein L33.
Protein: LEUC_BACAA
Sequence: MGKRLLDKLWERHVVTTNENGLDLLYIDLHLVHEVTSPQAFEGLRLTNRTVRRPDLTFATMDHNIPTKDVWNITDRIAKQQLDTLRENCKQFQVPLADIGDEEQGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPKAMGIELKGKLQKGVYAKDIILHLLSKYGVAVGTGYVMEFYGETIGTMEMEERMTLCNMAIEGGAKAGIIAPDEKTFAYVKGRKYAPRDYETFEKKWFELYTDADAIYDLHISIDVTDLAPYVTWGTNPSMGVRIDEKLPEKHDVNDERAFSYMGLIPGQSTYDIPVQHVFIGSCTNSRLSDLEIAASVVKGRKVKEGVRALVVPGSKRVRDAAMQKGLHHIFEEAGFEWREPGCSMCLGMNPDQVPEGEHCASTSNRNFEGRQGKGARTHLVSPAMAAAAALYGHFVDIRKESYDGAISYS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: FUB6_GIBF5
Sequence: MGGEVSNKTWVFKKSPSSLPEPGVHTAFEDRPLSLVAPPGGLVIKLLTAGLDPHQRDRMRGAGNVDYVPGYEVNEPITNFSIAKVIRSDNDVFEEGSLIAGSLPIAEYGIIPRELIDARAMASPLVWKVSNDYNLDVKHYVGTLGLAGMTAWNSFYGLVKAVKGETIWVNAASSSVGEVVVQLAKIEGMKVIASVSSDDKLDYVVNELGADVGFNYRKEPVGKALKPAIENMKWFGRIISCGTASQYNKPVEEQYGVTNLSEIFRRRIKIQGFIFWDDNIYTDNIENFKATMPKWVSEGKIKSRYTQFEGIEQADKAFLSMFTGGSHGKTVLKISDP
What is the function of this protein?
Dehydrogenase; part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties (PubMed:26662839).  L-aspartate is suggested as fusaric acid amino acid precursor that is activated and further processed to O-acetyl-L-homoserine by cluster enzymes aspartate kinase FUB3 and homoserine O-acetyltransferase FUB5, as well as enzymes of the primary metabolism (PubMed:26662839).  The polyketide synthase (PKS) FUB1 generates the triketide trans-2-hexenal which is presumptively released by the hydrolase FUB4 and linked to the NRPS-bound amino acid precursor by NAD(P)-dependent dehydrogenase FUB6 (PubMed:26662839).  FUB1, FUB4, and the non-canonical NRPS Fub8 may form an enzyme complex (PubMed:26662839).  Further processing of the NRPS-bound intermediate might be carried out by FUB6 and the O-acetylhomoserine FUB7, enabling a spontaneous electrocyclization to close the carbon backbone of fusaric acid (PubMed:26662839).  Dihydrofusaric acid is likely to be released via reduction by the thioester reductase (TR) domain of FUB8 whereupon the final oxidation to fusaric acid may (also) be performed by the FMN-dependent dehydrogenase FUB9 (PubMed:26662839).
What are the official names of this protein?
Dehydrogenase FUB6, Fusaric acid biosynthesis protein 6.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: BTPS1_METBS
Sequence: MEKQRLTAQLSSLRVPLFSVPWPGQCSNKAEVIEARMMKWADEHNLLVTDEYRNRVIRTRYGLLAARCYPNAGEELLQAIADCLVWFFLADDLFVDRVEVATDETIRNLTAMVDVLDLNVAGSPPVFGELAWLDVCQRLRRLLQAEAFERFAQGMRLWATTAALQILNHLRPTSVGMREYQTIRRHTSGMNPCTSLADAANKGSVQACEFYDADVQTLVRQTNNIVCWANDIQSLRIEIHQPGQFRNMVTIYAQQGQSLQDAVETTATRVNKEIASFCELADAVTARPISDELHGLIDGLKYWIRGYLDWVVHDTLRYADQFIESDADDRRF
What is the function of this protein?
Terpene synthase that catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into sesquiterpenes which are important for fungi-environment interactions (PubMed:31239482).  Produces a mixture consisting of 8 sesquiterpenes including corvol ethers A and B, as well as traces of epizonarene, gamma-cadinene, delta-cadinene, alpha-cadinene, alpha-cadinol, and an unidentified sesquiterpene (PubMed:31239482).  The major product is corvol ether B (PubMed:31239482).
What are the official names of this protein?
Sesquiterpene synthase MBR_10393, Bacterial terpene synthase-like protein MBR_10393, BTPSL.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: YCHJ_SHIBS
Sequence: MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQDADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTEGGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ
What are the official names of this protein?
UPF0225 protein YchJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: YJFA_BACSU
Sequence: MKRLFMKASLVLFAVVFVFAVKGAPAKAETHAYDGKSPYYNDCASSGSTKKSSNLVNASNQVIGVVELKFSSTCKTAWAKITMNNTLTSGYEANAEITRNTDGKRYNCDSAGGNGKAVAGQKSCYTPMVYDLDPRTSYAFGKYSGPNLNVWATTGSY
What are the official names of this protein?
Uncharacterized protein YjfA.
Protein: MBLC1_MOUSE
Sequence: MNGPVRTEPLHGEIPLLASSGSYSVVVLLRGYAEPQGAGDAVRADGTVTLVLPRGWASDSSRGLAPSADGGSKTALEEAVRGPILVDTGGPWARGALLEALATQGVAPEDVTLVVGTHGHSDHIGNLGLFPEAALLVSHDFCLPEGLYLPHGLCETQPLILGSGLQVWATPGHGGQRDVSVVVEGTSLGTVVVAGDVFERLGDEDSWQALSEDPVAQQRSRERILSVADVVVPGHGAPFRVVRETVKSSEDLICEGKAVA
What is the function of this protein?
Endoribonuclease that catalyzes the hydrolysis of histone-coding pre-mRNA 3'-end.  Involved in histone pre-mRNA processing during the S-phase of the cell cycle, which is required for entering/progressing through S-phase.  Cleaves histone pre-mRNA at a major and a minor cleavage site after the 5'-ACCCA-3' and the 5'-ACCCACA-3' sequence, respectively, and located downstream of the stem-loop.  May require the presence of the HDE element located at the histone pre-RNA 3'-end to avoid non-specific cleavage.
What are the official names of this protein?
Metallo-beta-lactamase domain-containing protein 1, Endoribonuclease MBLAC1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Localizes in the nucleus during early S-phase of the cell cycle.