PharMolix/UniProtQA huggingface dataset:
Protein: MURC_STAA2
Sequence: MTHYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALRNKGIKILPFDANNIKEDMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPIYYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIETARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSINVLEQFDNAVVLFMGAGDIQKLQNAYLDKLGMKNAF
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_CHRVO
Sequence: MARYIGPKCKLARREGTDLFLKSARRALDSKCKLDAAPGQHGARRGRLSDYGVQLREKQKIRRIYGVLERQFRNYFAEAVRRKGSTGENLLKLLESRLDNVVYRMGFGSTRAEARQLVSHKAIVVNGQVVNIPSYQVKAGDVVSVREKAKKQARIVEGLALAEQGGFPSWVSVDSKKMEGTFKSAPERSELSSDINEQLVVEFYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: XG74_ACETH
Sequence: MVKKFTSKIKAAVFAAVVAATAIFGPAISSQAVTSVPYKWDNVVIGGGGGFMPGIVFNETEKDLIYARADIGGAYRWDPSTETWIPLLDHFQMDEYSYYGVESIATDPVDPNRVYIVAGMYTNDWLPNMGAILRSTDRGETWEKTILPFKMGGNMPGRSMGERLAIDPNDNRILYLGTRCGNGLWRSTDYGVTWSKVESFPNPGTYIYDPNFDYTKDIIGVVWVVFDKSSSTPGNPTKTIYVGVADKNESIYRSTDGGVTWKAVPGQPKGLLPHHGVLASNGMLYITYGDTCGPYDGNGKGQVWKFNTRTGEWIDITPIPYSSSDNRFCFAGLAVDRQNPDIIMVTSMNAWWPDEYIFRSTDGGATWKNIWEWGMYPERILHYEIDISAAPWLDWGTEKQLPEINPKLGWMIGDIEIDPFNSDRMMYVTGATIYGCDNLTDWDRGGKVKIEVKATGIEECAVLDLVSPPEGAPLVSAVGDLVGFVHDDLKVGPKKMHVPSYSSGTGIDYAELVPNFMALVAKADLYDVKKISFSYDGGRNWFQPPNEAPNSVGGGSVAVAADAKSVIWTPENASPAVTTDNGNSWKVCTNLGMGAVVASDRVNGKKFYAFYNGKFYISTDGGLTFTDTKAPQLPKSVNKIKAVPGKEGHVWLAAREGGLWRSTDGGYTFEKLSNVDTAHVVGFGKAAPGQDYMAIYITGKIDNVLGFFRSDDAGKTWVRINDDEHGYGAVDTAITGDPRVYGRVYIATNGRGIVYGEPASDEPVPTPPQVDKGLVGDLNGDNRINSTDLTLMKRYILKSIEDLPVEDDLWAADINGDGKINSTDYTYLKKYLLQAIPELPKK
What is the function of this protein?
Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG.  Has low activity on carboxymethylcellulose, lichenan,hydroxyethylcellulose and glucuronoxylan, and no activity on xylan, polygalaturonic acid, wheat arabinoxylan, rhamnogalacturan, curdlan, laminarin, galactomannan, galactan, arabinan and pachyman or amorphous cellulose.
What are the official names of this protein?
Xyloglucanase Xgh74A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 74 family.
Protein: PAI3_ARATH
Sequence: MSTGISSDLHLHPRALNFSKTSKSGLSNRKVSFSSVGYAQNRKLSCSVSSTENVAPKDDDRGKDRPLVKMCGITSARDAAMAVEAGADFIGMIIWPHSKRSISLSVAKDISQVAREGGAKPVGVFVEDDENTILRAADSSDLELVQLHGNSSRAAFSRLVRERKVIYVLNANEDGKLLNVVPEEDGHLADWILVDSATGGRYLDQLLSFFALSHCNVFLRGTSYTITLVHETVCLSQVTEISRV
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase 3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CH602_MYCSK
Sequence: MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEKVTETLLKSAKEVETKEQIAATAGISAGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDAERQEAVLEDPYILLVSSKISTVKDLLPLLEKVIQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVISEEVGLSLETADISLLGQARKVVITKDETTIVEGAGDAEAIQGRVAQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQAAPSLEELNLTGDEATGANIVRVALEAPLKQIAFNGGLEPGVVAEKVRNSAAGTGLNAATGEYEDLLAAGVADPVKVTRSALQNAASIAALFLTTEAVVADKPEKSAAPAGDPTGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Secreted, capsule. Cell surface. Secreted, cell wall.
Protein: RLA0_LEIIN
Sequence: MPSITTAKREYEERLVDCLTKYSCVLFVGMDNVRSQQVHDVGRALRAKAEFMMGKKTLQGKIVEKRAQAKDASPEAKHFNDQCEEYNLLSGNTGLIFTNNAVQEITSVLDAHRVKRAARVGAISPCDVIVAAGSTGMEPTQTSFFQALNIATKIAKGMVEIVTEKKVLSVGDKVDNSTATLLQKLNISPFYYQVNVLSVWDRGVLFTREDLMMTEDMVEKMLMEGLSNVAAMALGAGIPTSSTIGPMLVDAFKNLLAVSVATSYEFEEHNGKELREAAINGLLAGSCSAAAEPAAAAPAAPSAAAKEEPEESDEDDFGMGGLF
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SYGB_RUTMC
Sequence: MNTKDFLLELGCEELPPKCLQQLSNAFTHNLTTELDKLKLSYSSVESFATPRRLAVLVSNLQLQQNDQIIERKGPSISAFDQDIEGFAKSCGVAKNVLVQKTFGKTQYYFFTKQQKGLKTIDLLESTVDIAIQNISIIKPMRWSNLDTYFVRPTHWLIMMLGSDVVPASIMGLASGNTTRGLRFTGERIFDITCAKDYQKILLERAQIEVDFNTRKEIIRKQVIQVAKNNNAIAVIDESLLDEVCALVEYPRAFSGNFSSKFLDVPEEALISAMKSHQKYFHMLDVDGNLMPVFISVANIESSNLSVIIDGNERVIRSRLADSEFFWTQDKAHTLESRLDKLNQVLFMKSLGSMGDKIKRIEIFSGYIATVIGANVKDSARAGLLCKSDLVTDMVGEFADLQGVMGGYYALNDGENKAVASAISEHYHPRFSGDSLPNTSEGLAVAIADKLDTVTGIIGIGQGPTGSKDPYALRRMALGLLRIMIESKLNLNLKELISKSLNENSSAVNINSVDDIYQFMMRRLRAYYKEQKVNIQVFEAVLAVCPESPYDFHLRVEALNTFTNNQAFENLIETNKRIANILKNYSNLLIKVDDSALVEVAEKALFKATKSLSKRILNSTNYTKNIQELIAFKDIIDEFFDKVMVNTDDVVLRQARLNLINWVRSLFLSVADVSHLSL
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_HALHL
Sequence: MPELPEVETTRRGLQVHLVGRTLQRVVVRQRQLRYPVPARVEAAVVGEEVVALERRAKYLLIRLGGGAWLLLHLGMSGSLRLVAETDAPGRHDHVDLVLNDGRAVRLTDPRRFGCLLLGDGDPQDHRLLRRLGPEPLGSAFDGAVLHRAARGRRVAVKALLMDATVVVGVGNIYANEALFRAGIRPDRAAGRIARARYDRLAGAVRAVLEAALAAGGTTLRDFTDGSGEPGYFAVNLSVYGASVCPVCGGALRQIRLAQRGTWFCPRCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: GCSP_MYCLB
Sequence: MSVPNSSNKQTCFTARHIGPNSEDVATMLAVIGVESLDDLAAKAVPSDILDNVTDTGVAPGLDRLPPPATESETLAELGALARANTVAVSMIGQGYYDTLTPAVLSRNILENPAWYTPYTPYQPEISQGRLEALLNFQTLVSDLTGLEIANASMLDEGTAAAEAMTLMYRAARSTASRVVVDVDVFAQTVAVFATRAKPLGIDIVVADLREGLPDGEFFGVITQLPGASGRITDWTALIAQAHSRGALVAVGADLLALTLITPPGEIGADVAFGTTQRFGVPMGFGGPHAGYLALHTKHARQLPGRLVGVSVDSDGTPAYRLALQTREQHIRRDKATSNICTAQVLLAVMAAMYASYHGAEGLTGIARRVHAQARALAAGLSAAGVEVVHQAFFDTVLARVPGRTVQIQGAAKERGINVWLVDGDHVSVACDEATTDEHITAVLAAFAATPARASFAGPDIATRTSAFLTHPTFTKYRTETSMMRYLRALADKDIALDRSMIPLGSCTMKLNAAAEMESITWQEFTRQHPFAPVSDTPGLRRLISDLESWLVQITGYDAVSLQPNAGSQGEYAGLLAIHDYHVSRGEPHRNVCLIPSSAHGTNAASAALVGMRVVVVGCHDNGDVDLDDLRIKLSEHANRLSVLMITYPSTHGVYEHDIAEICAAVHDAGGQVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVRSHLVSFLPGHPFAPELPQGQPVSSAPYGSASLLPITWAYIRMMGADGLRTASLTAIASANYIARRLDKYFPVLYTGENGMVAHECILDLRPITKSVGVTVDDVAKRLADYGFHAPTMSFPVPGTLMVEPTESESLAEIDAFCEAMIAIRGEIARVGAGEWSVEDNPLRGAPHTAECLLASDWDHPYTREEAAYPLGKAFRPKVWPPVRRIDGVYGDRNLVCSCLPVEAFV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: NADK_THEFY
Sequence: MKTSESTDRFGGVAGETTNRTVLLLAHTGRPAALRSARLVHESLTRAGVTVRMLASEIEAIRKTGARMQPVEVVEPGADAAAGTELIMVLGGDGTLLRAAELARPAGAPLLGVNLGHVGFLAEAERDDLSDTVRCVVERDYSVEERMTIDVAVYNGGRTSAAPAVRTWALNEATAEKVESGRMLEVVLEIDGRPLSRWGCDGVVCATPTGSTAHAFSGGGPIVWPSVEALLVVPLSAHALFARPLVVAPDAVIALEVLPETTDGVLWCDGRRRVELPAGARVEISRSKTPVRLARLQQAPFTNRLVAKFALPVAGWRGRAAERDSG
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOKA_ECOLI
Sequence: MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system (Probable).  When overexpressed kills cells within minutes; causes collapse of the transmembrane potential and arrest of respiration (PubMed:10361310, PubMed:20105222).  Its toxic effect is probably neutralized by antisense antitoxin RNA SokA (PubMed:10361310).
What are the official names of this protein?
Protein HokA.
What is the protein family that this protein belongs to?
Belongs to the Hok/Gef family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AGUA_ENTFA
Sequence: MAKRIVGSTPKQDGFRMPGEFEPQEKVWMIWPERPDNWRDGGKPVQEAFTNVAKAISQFTPMNVVVSQQQFQNCRRQLPPEITVYEMSNNDAWVRDCGPSFVINDHGEIRGVDWTFNAWGGLVDGLYFPWDQDDLVAQKICEIEHVDSYRTDDFVLEGGSFHVDGQGTVLTTEMCLLSEGRNPQLSKEAIEQKLCDYLNVEKVLWLGDGIDPEETNGHVDDVACFIAPGEVACIYTEDQNSPFYEAAQDAYQRLLKMTDAKGRQLKVHKLCCPVKNVTIKGSFKIDFVEGTMPREDGDICIASYMNFLITNDGVIVPQYGDENDHLALEQVQTMFPDKKIVGVNTVEVVYGGGNIHCITQQEPKR
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: YBEY_PETMO
Sequence: MKINVINQQELREINSKKIKDIAKKVLLNEVGKGNFELNILITDDKSITEFNKYRGKSTPTDVLSFSYGLSEPVIGDIVISVESIEKQAPDFGNSFEEEFYYILIHGLLHIVGYDHENSEEDAKKMFEVQDQYFHQLIKDRRR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_ANASK
Sequence: MAVVLRLSRAGTHKAPFYHVVATDSRNARDGKYLEDVGIYDPTKRPERIELKVERIEHWLKAGAKPSQTVAMILKRAAKAAAPVAPKA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ALF1_STAA8
Sequence: MNKEQLEKMKNGKGFIAALDQSGGSTPKALKEYGVNEDQYSNEDEMFQLVHDMRTRVVTSPSFSPDKILGAILFEQTMDREVESKYTADYLADKGVVPFLKVDKGLAEEQNGVQLMKPIDNLDNLLDRANERHIFGTKMRSNILELNEQGIKDVVEQQFEVAKQIIAKGLVPIIEPEVNINAKDKAEIEKVLKAELKKGLDSLNADQLVMLKLTIPTEPNLYKELAEHPNVVRVVVLSGGYSREKANELLKDNAELIASFSRALASDLRADQSKEEFDKALGDAVESIYDASVNKN
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: TAUE2_ARATH
Sequence: MRNNFVPIILSFIIFLTPSIAEQEPSILSPVDQLLNKTSSYLDFSTKFNQPRIELTTSTIIAGLLSFLASSISSAGGIGGGGLYVPIMTIVAGLDLKTASSFSAFMVTGGSIANVGCNLFVRNPKSGGKTLIDFDLALLLEPCMLLGVSIGVICNLVFPNWLITSLFAVFLAWSTLKTFGNGLYYWRLESEMVKIRESNRIEEDDEEDKIESLKLPLLEDYQRPKRFPWIKLGVLVIIWLSYFAVYLLRGNKYGEGIISIEPCGNAYWLISSSQIPLTLFFTLWICFSDNVQSQQQSDYHVSVKDVEDLRSNDGARSNKCMFPVMALLAGVLGGVFGIGGGMLISPLLLQVGIAPEVTAATCSFMVLFSSTMSAIQYLLLGMEHTGTASIFAVICFVASLVGLKVVQKVITEYGRASIIVFSVGIVMALSIVLMTSYGALDVWNDYVSGRYMGFKLPC
What are the official names of this protein?
Sulfite exporter TauE/SafE family protein 2.
What is the protein family that this protein belongs to?
Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARGR_STAAC
Sequence: MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSRDIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPGNAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_META1
Sequence: MYTSLISIKEKYELLAQELTKLEIFNDIKKYTKIQKEHASIEDIAIAFINYLAAESSYNLSKEILQNEKDEELIALAKEDIDEQSTLMQKLEQELKELLLPQDENDNKNVIMEIRGAAGGDEGDIFSGDLFKMYQKFCEANDFKIKIVDSVYGTAGGYSRIVFIVKGEKVFSKLKFERGVHRVQRVPQTETQGRVHTSTATVTVLPEVDDDVKIEIRPEDIEVDVFRSSGAGGQSVNTTDSAVRITHKKTGIIVTSQDERSQIMNRETALKILKAKLYEIEVKKREEEEQGLRKLAGTGDRSEKIRTYNYPQDRITDHRIGFSLSLKNVMEGNLDKIIDALIADEKALKIKAAGF
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2156_YERPN
Sequence: MDMTNAQRLILSNQYKMMTMLDPENAERYRRQQTIVERGFGLQMRELDRDFGEMSEDTCRTIINIMEMHHALQVSWGNLKEKQDLDERRISFLGFDAATESRYLSYVRFMVNTEGRYTHFDSGTHGFNSQTPMWDKYQRMLAIWQSCPRQYHLSAVEISQIINA
What are the official names of this protein?
UPF0304 protein YPN_2156.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: 148R_IIV6
Sequence: MLLKIKIKIRLFEKRYTIYFFLLKGKNKEEMEIIKKEFEHLVISELESSMLQKALDYSLTIVDIIKFVEITNFDIDPFMIDKFWHTMYDNSLLYISRDILEWMGYTGEFGEQRKAFKKLLKRKNINFTELSNNDPTKHLYPEIQKDSLLLSNAVVSQSKWIIMNSDDFKDSILMLNTKNSGKIRKYYRSFEKLLKLNLLYTLKFRERADKMQISSLETMMEEMRLERKQSEERSIKQEQLLLSIGYNLKELQEQKEEDTQKIDVLIDQNEDLKQNIEETNDKLDSVVEKLGIAVEDRAPRLKRASIRERFVLFKKNNSTNEIYQYYAIRGQSVYVNGRLSKLQSEKYPDMIILIDIICQPNPRNLFLRFKERIDGKPEWENNFIYAGNNVGCSFKLEKEMINIFKSLDEEKRDV
What are the official names of this protein?
Putative MSV199 domain-containing protein 148R.
Protein: COX1_BACP3
Sequence: MSTIARKKGVGAVLWDYLTTVDHKKIAHLYLISGGFFFLLGGLEALFIRIQLAKPNNDFLVGGLYNEVLTMHGTTMIFLAAMPLVFAFMNAVVPLQIGARDVAFPFLNALGFWMFFFGGLFLNCSWFLGGAPDAGWTSYASLSLDSKAHHGIDFYTLGLQISGFGTIMGAINFLVTIINMRAPGMTFMRMPMFTWATFVTSALILFAFPPLTVGLIFMMMDRLFGGNFFNPAAGGNTIIWEHLFWVFGHPEVYILVLPAFGIFSEIFATFSRKRLFGYSSMVFATVLIAFLGFMVWAHHMFTVGMGPIANAIFAVATMTIAVPTGVKIFNWLFTMWGGSIKFTTPMHYAVAFIPSFVMGGVTGVMLASAAADYQYHDSYFVVAHFHYVIVGGVVFALLAGTHYWWPKMFGRMLNETLGKITFWLFFIGFHLTFFIQHFLGLTGMPRRVFTYLPHQGWETGNLISTIGAFFIAAATVILLINIVVTTAKGEKVPGDAWGDGRTLEWAIASPPPVYNFAQTPLVRGLDAFWLEKMEGKKELTPAEPLGDIHMPNSSFLPFVIAFGLFVAAFGFTYHNDAGWGLPVAILGLLITLGSMFLRSVIDDHGFHIHKEEVLEL
What is the function of this protein?
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Subunits 1-3 form the functional core of the enzyme complex.  Co I is the catalytic subunit of the enzyme.  Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B.  This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome aa3 subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPB_THEP3
Sequence: MSGRFGRFGGQYVPETVMNALIELEREFEKAKEDKDFMEEYRYYLREYSGRPTPLYYAENLTKRLGGAKIYLKREDLNHTGAHKINNVLGQILLAKRMNKKRVIAETGAGQHGVATATAAAMFGMECEIFMGEEDIKRQSLNVFRMKLLGAKVTPVTTGTKTLKDAVNEAIRDWVTNIDNTFYVIGSVVGPHPYPTMVRDFQRVIGDEAKEQILQKEGRLPDYVIACVGGGSNAMGIFYPFIEDKEVKLIGVEAAGEGIETGKHAAAMAKGSVGVLHGMMTYLLQDEEGRIMPVYSISAGLDYPGVGPEHAFLKESNRAQYVYATDEEALAAFMDLSQTEGIIPALESAHALAYAMKLAPNLTKDNIIIVNLSGRGDKDVNTVAKVLGVEL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: NSF1C_MOUSE
Sequence: MAEERQDALREFVAVTGTEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPSDNRVTSFRDLIHDQDEEEEEEEGQRFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGERRRHSGQDVHVVLKLWKTGFSLDNGDLRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLNTSSPAQQAENEAKASSSILINEAEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFVLMTTFPNKELADENQTLKEANLLNAVIVQRLT
What is the function of this protein?
Reduces the ATPase activity of VCP.  Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis.  May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).  Inhibits the activity of CTSL (in vitro).  Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase.  Also, regulates spindle orientation during mitosis.
What are the official names of this protein?
NSFL1 cofactor p47, p97 cofactor p47.
What is the protein family that this protein belongs to?
Belongs to the NSFL1C family.
What are the subcellular locations of this protein?
Nucleus. Golgi apparatus, Golgi stack. Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Predominantly nuclear in interphase cells. Bound to the axial elements of sex chromosomes in pachytene spermatocytes. A small proportion of the protein is cytoplasmic, associated with Golgi stacks. Localizes to centrosome during mitotic prophase and metaphase.
Protein: PDXJ_MICAN
Sequence: MLTLGVNIDHVATIRQARRTVEPDPVAAAVLAEIGGADGITVHLREDRRHIQDRDVRILRQTVRTHLNLEMAPTEEMIAIALDIKPDYVTLVPEKRQEVTTEGGIDMLGNFDRFCRVVERLQAANIPVSWFIDADFAQIQAAANTGAKFIELHTGQYAEAQQESDRQALLTILKEGCEYASSLGLRVNAGHGLTYGNVYAVACLPNMEELNIGHTIISRAVLVGLERAVREMKLAMRGQL
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTAI2_HUMAN
Sequence: MAETEALSKLREDFRMQNKSVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQEVVDFEKLDDYASAFQGHDVGFCCLGTTRGKAGAEGFVRVDRDYVLKSAELAKAGGCKHFNLLSSKGADKSSNFLYLQVKGEVEAKVEELKFDRYSVFRPGVLLCDRQESRPGEWLVRKFFGSLPDSWASGHSVPVVTVVRAMLNNVVRPRDKQMELLENKAIHDLGKAHGSLKP
What is the function of this protein?
Oxidoreductase required for tumor suppression.  NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors.  May act as a redox sensor linked to transcription through regulation of nuclear import.  Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties.  Isoform 2 has an antiapoptotic effect.
What are the official names of this protein?
Oxidoreductase HTATIP2, 30 kDa HIV-1 TAT-interacting protein, HIV-1 TAT-interactive protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus envelope.
Protein: SYD_BUCAT
Sequence: MRTKYCGNIRISHVNKKVKLCGWVHKVRNLGQFIFVDMRDYTGLVQVIFELKNYTIFKKALNLRNEFCIQVFGTVQKREKKNQNIKIRTGEIEILANVLNILNTSKSLPLNFTQENNDDSRLKYRYLDLRSFDILENLKIRNKITYLIRNFMTKKNFLDIETPILTKSTPEGARDYLVPSRNHYGKFYALPQSPQLFKQILMISGIDRYYQIVKCFRDEDLRSDRQPEFTQIDIEVSFMSAKKIRNLVENLIKKLWLEIRNINLKKFPQISFHEAMKKYGSDKPDLRNPIEIIDVSNIFKDKKFISFFNLNPQKNNRIALLCISKGAHLSRKKIDDYTKYVQRFDAKKLFYIKIKECKLGCLGIHSSIKNILDEIILKEIIEKSQSKNGDILFLIADQEHIVNKSLGMLRLKIGIDLNITKKNRWEPLWIVNFPMFDKDIQGNLSSVHHPFTAVKNMDREILKNSPDLAISDSYDLIINGYEIGGGSVRIHDVNMQKQVFDIIGIKKSMQNEKFGFLIEALKYGAPPHAGIALGLDRIVMLLTNSKNIRDVIAFPKTTSATCLMTNSPSTVDNLLLQELAIKHLKK
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM6_YEAS6
Sequence: MLGLKGCLTILIGYVIAVCALFSSRGRNPSLTDWEKLKDQKISNIDNFGLTGQHLLAFFQENLPFLSFSEEKYRHKHVSLYYDVFKEYILRRASSKKCLPVDSAIAKLNKDVNPMPVHSHNDYWRKLPLFEGLAYGASSTEADVWNIDEKILAVGHNEAYLDPVELTLDKLYTGPLLEILDEVNCQDSDSDRKNGVFFNSPETSLFFYIDFKSDDNELTYKLLMEQYFKSLIDSGYLTYYDMKKDEIIWRPVTVILTGNYPTSLDILDNGNDNGYFESSQRFAFLDAPLLSLEPKYSKLSVAATVSFSQLMKHCGSDHWKVSLRGRMDSNEISCAKSIIDGAHALKLKTRIWGAPTWPANLVETISRQIIHDLGSDLLNLDNLFMASSLI
What are the official names of this protein?
Altered inheritance of mitochondria protein 6.
What is the protein family that this protein belongs to?
Belongs to the AIM6 family.
Protein: ASTB_ECODH
Sequence: MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQGLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFSVHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATQVSVSDTVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGYLNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFNALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.