PharMolix/UniProtQA huggingface dataset:
Protein: IF2_BRADU
Sequence: MVDTKTPGDKKLSVPSKTLSLKPRVETGTVRQSFSHGRSKQVVVEKRGKRRIGDGPEPHAPEVTAKPAPAAPAPSRPAPPPAPPRNAGSGVVLRTLTEDERSARASALADAKLREVEERRQAEEEAQRRAVREAAERAEREAAEARRKAEDERHRHEDEAKRKAETEAKKRFGEGEQPASAARPATAAPAAPAPRPGAPAARPGTTTTRPGTTTARPATTTAQRPGAPAGRGPAVAAEPDEDEAPRQIRRGPGGAARPAPPPKTTHKPGPQKERGRLTVVTALNADEVRERSIASFRRRTQRLKGHASNEPKEKLIREVIIPEAITIQELANRMAERAVDVIRMLMKQGAMHKITDVIDADTAQLIAEELGHTVKRVAASDVEEGLFDQVDDSTDTETRSPVVTVMGHVDHGKTSLLDALRHANVVSGEAGGITQHIGAYQVVSPESGKKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQTVEAINHAKAARVPIIVAINKIDKPDAKPERVRTELLQHEVQVESFGGDVVDVEVSAKNKTNLDKLLEMIALQADILDLKTNSERPAEGTVIEAKLDRGRGPVATVLVQRGTLRVGDIIVAGAEMGRVRALISDQGETVQEAGPSVPVEVLGFNGPPEAGDRLAVVENEARARQVTSYRAHQKRENAAASISGMRGSLEQMMSQLKTAGRKEFPLIIKADVQGSLEAILGSLEKLGTDEVAARILHAGVGGISESDVTLAEGFNAAIIGFSVRANKEAAAAAKRNGIEIRYYNIIYDLVDDVKKAMSGLLAPTLRETMLGNAAILEIFNISKVGKVAGCRVTDGTVERGANVRLIRDNVVVHEGKLSTLKRFKDEVKEVQSGQECGMAFENYHDMRAGDVIECYRVETIQRSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S39AD_DROME
Sequence: MTTNSSFFDEHIAMIYSNLMDQYMPEYFKSFEYTPWVFSLLGSVVIGLSGIFPLIIIPTEEKMAKEGYKDPADSKLLRVLLSFAVGGLLGDVFLHLLPEAWEGDNQDPSSHPSLRSGLWVLSGILIFTIVEKIFSGYASADEENPQPKCVEIANCLLRRHGGQLPEGETSESCGGACDIEDVGKVCFLREQEQKSKERKEQPKKVAGYLNLLANSIDNFTHGLAVAGSFLVSFRHGILATFAILLHEIPHEVGDFAILLRSGFSRWDAARAQLLTAGAGLLGALVAIGGSGVTSAMEARTSWIMPFTAGGFLHIALVTVLPDLLKEEERKESIKQLLALVFGIALMAVMTMLFEH
What is the function of this protein?
Involved in zinc transport and homeostasis.
What are the official names of this protein?
Zinc transporter ZIP13 homolog, Zinc/iron regulated transporter-related protein 99C.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Also detected on intracellular membranes.
Protein: ERF1_GIAIN
Sequence: MSINPDAPQSNGEQERQIAIWQLKRTIEKLESYTGSGTSVISLLIPPGEQLSSVTGMLTNEYGTASNIKSRVNKNAVLSAITSAMSRLKLYNRLPPNGLAVYCGEIEEDGKNTKVVIDYTPYKPISNFIYLCDSKFHTEHLRELLTNDDTFGFIIMDGKETLMATLSGTVRTILDRSTVDLPKKHGRGGQSSVRFARLREEARHNYVRKVAERANSLFISSGPTGTNKPIVSGLILGGSADFKNVLSTSAIFDQRLQSIVMKQIDINYGGEQGFNQAIEMAGDTLKDVKLIQEVKLLTEFTENIAKDTKRVCFGITDTIRCLEMSAVEKLIVWDDLPYHRVTLQCVINGETSAPVIKYLLKSQMSNPKYLREVINGEEVQLDIMGDQLLLEWFVDNYKNYGASLEFITNRSAEGTQFCSGFGGIGGLLRWQVDLVEAARFMQESDEDSFMDDLEDFI
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, eRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSL_LIMPO
Sequence: MANQLSYSSLGWPYQPNASVVDTMPKEMLYMIHEHWYAFPPMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFMMPTMTSNCFAETWILGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAAAPLTHKKATLLLLFVWIWSGGWTILPFFGWSRYVPEGNLTSCTVDYLTKDWSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKKMNVASLRANADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVFSSGTRLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLACGSGESGSDVKSEASATTTMEEKPKIPEA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Lateral eye opsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: INS1_CONKI
Sequence: MTTSSYFLLVALGLLLYVCQSSFGSPHTSDSGTTLVRRRLCGSELVTYLGELCLGNRKRRGFPSMLKARAKRNEAFLLQRDGRGIVEDCCYNDCTDEKLKEYCHTLQG
What is the function of this protein?
This venom insulin, from a fish-hunting cone snail, facilitates prey capture by rapidly inducing hypoglycemic shock (PubMed:30747102).  It is one of the smallest known insulin found in nature and lacks the C-terminal segment of the B chain that, in human insulin, mediates engagement of the insulin receptor (INSR) and assembly of the hormone's hexameric storage form (By similarity).  Despite lacking this segment, it both binds and activates human insulin receptor (long isoform (HIR-B)) with a moderate potency (EC(50)=30. 45 nM) (PubMed:30747102).  In vivo, intraperitoneal injection of this peptide into zebrafish lowers blood glucose with a lower potency than human insulin (PubMed:30747102).  In addition, when applied to water, this peptide reduces overall locomotor activity of zebrafish larvae, observed as a significant decrease in the percentage of time spent swimming and movement frequency (By similarity).  When tested on a mouse model of diabetes, this insulin also lowers blood glucose with a 20-fold lower potency than human insulin (PubMed:30747102).
What are the official names of this protein?
Con-Ins K1, Insulin K1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_SORC5
Sequence: MQLRAEEISQIIKKQIQNIDKAAQVTETGTVLTVGDGIARVHGLSRAMAGELVEFTGSEGGSLMGLVLNLEQDNVGAAIFGDTSSIKEGDAVKRTGRIMEVPVGEATLGRVVNALGMPIDGKGPLETKERRRVEVKAPGIIQRQPVTEPMQTGIKAIDAMIPVGRGQRELIIGDRQTGKTAVAVDAIINQKGKGVICVYVAIGQKLSTVRQVVDKLDAHGALEYTIIVAATASETAPLQFIAPYTGVTIGEYFRDSGRHALCIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKMADVFYVVSKGTKIEGGDASYRGIDGKAHVGAHGMHSAKDSLWKTIDGALFEKLEQARKDEKKDEIKKLEQQLSDKAKASDYEIVRDPKSGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLEADLFYSGVRPAINVGISVSRVGGNAQIKAMKSIAGTLRLDLAQYRAMAAFSQFASDLDAKTRAQLERGARLTEILKQGQYVPLAVEKQILIIYAGTQGLLDSLPVSSLSRFEEELYKFVEAKHPQIFTDIREKKVLDDDLKSRMTKAIDTFKKRFAVEAGGASTAADEDGAGDDEEEAPAPKAKSKNAKSASKAKEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PEPF_BORBU
Sequence: MINRNEINENDKWDLSFLFANEEEYVKTINAIEIKTKEFKKYEKLELNFDLFKETLNKYYEIMEDLEKVSYYAMLQLETDVTNKDSNKIYSICVNLATKVSNTTSYFMPKILKTDEKKIQAWINDPELKDKKIAIEKILREKKHILSEQEEKILANYTPLYTSYQSIFSALTNADMEFGEINKHPLTNSTYTLFLQNEDQKIRKEAFLRFYQKYKNNENTLANLIISDFKKNHFIAKTRRFQNTFSMQLFSNNIDKKVYTNLIETVNENLPVLNDYYEFRKKVLNQEYLYHYDVYVPLTKGIIFKNSFEDACEKILKSLEVLGNEYTKILRNGLLKERWVDKYENTGKRSGAFSAGSYNGKPYILLNYKDESIRDMFTLAHEAGHSMHSYFSIKNNPFPHYNYSIFEAEIASIINEQILAEYLLKNETDTNKIKYIKLTQIDDMISTFFRQTMFAEFEYIIHEMISKEEPVVKETLTETYMNLLKKYFGPSLKFDELSPLECLRIPHFYSPFYVYQYATGIAAALSIYKGIKENKKDAVENYIKFLKTGGSKYPLDSLNITGVDLTKKATIENTINIFKCRLEEIKKIFQ
What are the official names of this protein?
Oligoendopeptidase F homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3B family.
Protein: UREF_PROM9
Sequence: MTKSHLLKYLLTSPNLPVGGFCYSEGMESYLHNKNLNDSNSVKELIISELKIGQIRLDAKLLLDFFDIFNEINDGKNAKSNLQKLLSLNKWILSSKDSIEMREQQTQMAKSLFDLTKEFGFEYLYENNKKSSWPLAWSWACFCFEITKIEMVENFFYAWSANQLSAALRIIPIGSTKTQLIQRDLLAIISKVSKEIMDKQIDDIYFGNVGLAMAQQNHNDLYTKLFRN
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC11_CHAGB
Sequence: MLSSLQNPRQAAAQLMNFGLILSTAFMMWKGLSVITDSPSPIVVVLSGSMEPAFQRGDLLLLWNRNLISETNVGEIVVYNVKGKDIPIVHRIVRKFGVGPDAKLLTKGDNNAADDTELYARGQDYLNRKDIVGSVVGYMPFVGYVTIMLSEHPWLKTVMLGIMGLVVVLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: OTC_ECOHS
Sequence: MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE1_PSEPF
Sequence: MAILIGERPAQALWRDYLELTKPKVVVLMLITSLVGMFLATRAGVPWTVLVFGNLGIALCAGGAAAVNHVVDRRIDAVMARTHKRPLADGRVSPTGALTFALVLALLGQALLLTFTNPLTAWLTLASLLGYAVIYTGFLKRATPQNIVIGGLAGAAPPLLGWTAATGHVSAEPLLLVLIIFAWTPPHFWALAIHRKEEYAKADIPMLPVTHGEHYTKVHILLYTFALLAVSLLPYVIHMSGLLYLICALGLGARFLQWAVVLYRGTRPHAAINTFKYSIWYLFLLFIALLVDHYLLLNL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 1, Heme B farnesyltransferase 1, Heme O synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PESC_LEIIN
Sequence: MAHKKQAWAKRVKKERFKKKFLTRMQATRLLQMESVQFRRLCILKGIYPRALNRSKQKQSGHEKQYYLAREIKWLVRDQIAEKMMAYRAWEKKVKRAEAMGRSEDLKVLQSSRVKPRHSLVATIKERYPYFIDAIRDVDDAMSMIHLYAFLSPEIKSDTTIEIHHSLTSGMSEKAKEVCERWDRYVARARVLTKGFISIKGYYYEAIVKGERVRWLCPHEYAHRFPPGIQQYVMLSFLEFYLEMMKFVLFKLESDLARDEADRLAAEDEEGVTRANAEDFANGGALAVLDVGANGAQAKEVKEAESKRSLMGEELHKVRELFRGLTFFISREVPSKRFALVINACGGRVATDYVPSNITHVVVDRPALPPGMKKHDQLEYVQPQYIFDCLNARLMLPVTGYRIGEELPPHVSPFSVSITNSAEDNAAVEQVKKDHPRIVGYVPARVHEIRKLINPSYSAVDPEGKVAHLEGEYSDEESHVAVPEMDMEDDVSLSGDELAEARRKPAWQEEEVTEEVQRPKLSAFKVKKQREMNLMNAPTNEVVARRRQALRKAQEKSRQTETSEARLQRKMSEVKRQEAATRKMQLQVARKKAARFYKMISGVVQGTAKKAATLEAKAKHIAEGKLHKTEDGKGLVNTRLEARRQRAEAKSKKLKERKAGNPYKKLPKWVQ
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: B3GT1_PONPY
Sequence: MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVARKNFTFGNIRTRPINPHSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWGDENNFKGIKIATLFLLGKNADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDIFVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTGYIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLGIHPFQNSGFNHWKMAYSLCRYRRVITVHQISPEEMHRIWNDMSSKKHLRC
What is the function of this protein?
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue.  Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins.
What are the official names of this protein?
Beta-1,3-galactosyltransferase 1, Beta-1,3-GalTase 1, Beta3Gal-T1, Beta3GalT1, UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: SYP_HALMA
Sequence: MSGEQELGITESKEHSPGEWYAEVVQKAGLADYAPMGGFIVTRPRGYAIWERIQNNLDGWFKDTGVQNAYFPLFIPESYLEKEKDVVEGFDPEVAWVTHGGHNELEERLAVRPTSESIIAPFMAQWTRSHRDLPMRLNQWCSVVRWEATETKPFFRTKEFLWQEGHTAHADEDGAWEETMTRLDQYARLYEEVMAMPPLKGRKPPHDKFPGAHTTTTIETLMPDGKTVQAATSHYLGTSFGEAFDITYADADEEENTAHTTSWGLSWRAMGALIMTHSDDQGLVLPPALAPDQVVVVPIWQEDNKDEVIDYAADLAAELDEADVRVELDDREHRNPGFKYNEHELHGVPLRVEIGPHEVEDGEATLVHRPDGETETVDRDGIADTVTDHLDTVHAKLYASAEETLEGEIREAESREEILGTIGQHGGYVKCGWCGDEDCEEPIKDAIAAEIVMVPLDRDEEPIHEDCAICGEDAEETAYFAKSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CILK1_MOUSE
Sequence: MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQIGHPLGIISKDSGKPQREVQDKTGPPPYIKPAPPAQAPAKAYTLISSRPSQASQPPQHSVHPYKGDVSRTEQLSHVQEGKPSPPFFPSLHNKNLQPKILASLEQKNGEIKPKSRRRWGLISRSTKGSDDWADLDDLDFSPSLTRIDVKNKKRQSDDTLCRFESVLDLKPSESVGTGTTVSTQASSQRRDTPTLQSSAKQHYLKHSRYLPGINIRNGVLPNPGKDFLPSNSWSSSGLSGKSSGTVSVVSKITSVGSGSASSSGLTGSYIPSFLKKEIGSVMQRVQLAPLAAPPPGYSSLKAVRPHPGRPFFHTQPRSTPGLIPRPPAAQPVHGRIDWSSKYPSRR
What is the function of this protein?
Has an essential role in ciliogenesis, particularly in neuronal and retinal progenitor cells (PubMed:24797473).  Phosphorylates KIF3A (PubMed:24797473).  Involved in the control of ciliary length (PubMed:24853502).  Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (PubMed:24797473, PubMed:24853502).  May play a role in cardiac development (By similarity).  Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling -dependent manner and this regulation requires its kinase activity (PubMed:25243405).
What are the official names of this protein?
Serine/threonine-protein kinase ICK, Intestinal cell kinase, mICK, MAK-related kinase, MRK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, cilium. Nucleus. Cytoplasm, cytoskeleton, cilium basal body. Note=Also found at the ciliary tip (PubMed:24797473). Predominant nuclear localization has been observed with a N-terminally GFP-tagged construct in transfected COS-7 cells (PubMed:15988018).
Protein: EBNA3_EBVG
Sequence: MDKDRPGDPALDDNMEEEVPSTSVVQEQVSAGDWENVLIELSDSSSEKEAEDAQLEPAQKGTKRKRVDHDAGGSAPARPMLPPQPDLPGREAILRRFPLDLRTLLQAIGAAATRIDTRAIDQFFGSQISNTEMYIMYAMAIRQAIRDRRRNPASRRDQAKWRLQTLAAGWPMGYQAYSSWMYSYTDHQTAPTFVQLQATLGCTGGRRCHVTFSAGTFKPPRCTPGDRQWLYVQSSVGNIVQSCNPRYSIFFDYMAIHRSLTKIWEEVLTPDQRVSFMEFLGFLQRTDLSYIKSFVSDALGTTSIQTPWIDDNSSTETAQAWNAGFLRGRAYGLDLLRTEGEHVEGATGETREESEDTESDGDDEDLPCIVSRGGPKVKRPPIFIRRLHRLLLMRAGKRTEQGKEVLEKARGSTYGTPRPPVPKPRPEVPQSDETATSHGSAQVPEPPTIHLAAQGMAYPLHEQRGMAPCPVAQAPHTPLPPVSPGDQLPGVSSDGRVACAPVPAPAGPIVRPWEPSLTQAAGQAFAPVRPQHMPVEPVPVPTVALERPVYPKPVRPAPPKIAMQGPGETSGIRRARERWRPAPWTPNPPRSPSQMSVRDRLARLRAEAQVKQASVEVQPPQVTQVSPQQPMEGPGAPFSQVADVVHTPGVPAMQPQYFDLPLIQPISQGAPVAPLRASMGPVPPVPATQPQYFDIPLTEPINQGASAAHFLPQQPMEGPLVPEQWMFPGAALSQSVRPGVAQSQYFDLPLTQPITHGAPAAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDVVQHQLDALGYPLHALNHPGVPVSPAVNQYHLSQAAFGLPIDEDESGEGSDTSEPCEALDLSIHGRPCPQAPEWPVQGEGGQDATEVLDLSIHGRPRPRTPEWPVQGESGQNVTDHEPRRVVVSAIVHMCQDDEFPDLQDPPDEA
What is the function of this protein?
Plays an essential role for activation and immortalization of human B-cells.  Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters.  Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop (By similarity).
What are the official names of this protein?
Epstein-Barr nuclear antigen 3, EBNA-3, EBV nuclear antigen 3, Epstein-Barr nuclear antigen 3A, EBNA-3A, EBV nuclear antigen 3A.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae EBNA-3 family.
What are the subcellular locations of this protein?
Host nucleus matrix. Note=Associated with the nuclear matrix.
Protein: EX7L_CROS8
Sequence: MPLTQTPSIFTVSRLNQSVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQRYEQLKQQLAAEGLFDPALKKPLPSPARQVGVITSKTGAALHDVLNVLRRRDPSLPVVIYPTAVQGDDAPAQIVRAIELANLRDECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPIVSAVGHETDVTIADFVADLRAPTPSAAAEIVSRNQLELLRQVQALQQRLEMAMDYSLANRQQRFTRLHHRLEQQHPQLRLARQQTLLMRLRQRMDNALDSRMRHATQRQTRLMQRLNQQQPLPRLHRASARVQQLEYRLGQIVAARLSHTRERFGNAITHLEAVSPLATLARGYSVTTAQDGNVLKATKQVRPGDTLTTRLADGWVESEVRQITPAKKTRKKKTG
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSP_CUPNH
Sequence: MRITQGTFSFLPDLTDAQITSQLEYCLNQGWAVGIEYTDDPHPRNTYWEMFGLPMFDLRDAAGILLEINNARSTFPNHYIRVTAFDSTHTVESVVMSFIVNRPADEPGFRLVRQEEPGRTIRYSIESYAVQARPEGSRY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, plasmid, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
Protein: PROB_BORPE
Sequence: MTAQTSAVSVISAANRLVAKVGSSLVTNEGRGLDRAAVGHWAAQIAALHQQGKQVVLVSSGAIAEGMARLGWRKRPSAMHELQAAAAVGQMGLCQAYEAAFAEFGLRTAQILLTHEDLADRHRYLNARSTLFALLRLGVVPIVNENDTVVTDEIRFGDNDTLGALVTNLIEADALIILTDQRGLYEADPRRDPAARFVAHAQAGDAALEAMAGGAGSGVGTGGMLTKILAAKRAAHSGAHTVIASGRERNVLTRLAQGECIGTELRAVLPVWSARKQWLADHLRLRGRVVLDDGAVHALLHEGKSLLPIGVAEVQGEFERGDVVACVDMHGRECARGLINYSSADTRRILRQPSSQIARILGSMTDPELMHRDNLVVT
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN2_RAT
Sequence: MMNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPAPGPGTATASAATSAASPGPERRPPPAQAPAPQPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLVDAPAPSAASRKAKVLLVVDEPHTDWAKCFRGKKILGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVVRSFRPDFVLIRQHAFGMAENEDFRHLVIGMQYAGLPSINSLESIYNFCDKPWVFAQMVAIFKTLGGEKFPLIEQTYYPNHREMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVVALTQTYATAEPFIDAKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKLWVDACSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITDLVISKMNQLLSRTPALSPQRPLTTQQPQSGTLKEPDSSKTPPQRPAPQGGPGQPQGMQPPGKVLPPRRLPSGPSLPPSSSSSSSSSSSSSAPQRPGGPTSTQVNASSSSNSLAEPQAPQAAPPQKPQPHPQLNKSQSLTNAFSFSESSFFRSSANEDEAKAETIRSLRKSFASLFSD
What is the function of this protein?
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release.  May play a role in noradrenaline secretion by sympathetic neurons (By similarity).
What are the official names of this protein?
Synapsin-2, Synapsin II.
What is the protein family that this protein belongs to?
Belongs to the synapsin family.
What are the subcellular locations of this protein?
Synapse.
Protein: NADK_DESOH
Sequence: MKTIGLVVKTDPEAARNADELEKWLAGRGVGVVRTGSVSDDRKAPVDLGCVFVLGGDGTFLSAARWIGDAPIPLVGIKFGGVGFLSETVEDDLFSAAEKILKGEFTIAKRMRLRVTIYENGQEQARRTVLNDVVINKGALARLAHIHTFVDGYDLTTYHGDGLIVSTPTGSTAYSLAAGGPVIHPAVPGIILTPICPFTLTNRPLVVPDSVRIELRLAQSPSDIMVTLDGQEGFEMTEGHRLMIEKAAHPVHMIILPGQRYFDVLKTKLKWGGGPAGY
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAT_BACCR
Sequence: MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFHSDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTVRRWAYDVKKVEANRAEIIVCEDNFHGRTMGSVSMSSNEEYKRGFGPMLPGIVVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGYLKEAFEVCKKENVLFVADEIQTGLSRTGKVFACDWDNVTPDMYILGKALGGGVFPISCVAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTNLP_ARATH
Sequence: MDSLSDIDGDFDGRNEGGSSSDYRLLGRQITVHQFMGGGKAADLLLWRRRHLSLGVIIISTVAWLIFEFSGLPFLSVSSDVLLIVIMISFVHARVSAFRNRQLHSLPELVLSEEMVNSAAASFRIKLNHLLVMAHDVTVGNDFRLFFKVVICLWLLSAIGSYISLCTLLYIGTILSVTIPALYSKYQSKVDKCCGTIHRRLSHHYKIVDENVISRLSWSLSKDKDS
What are the official names of this protein?
Reticulon-like protein B16, AtRTNLB16.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.