PharMolix/UniProtQA huggingface dataset:
Protein: YAJL_ECOLI
Sequence: MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLAITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIVAAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWLDKRVVWDARVKLLTSQGPGTAIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals (PubMed:26774339, PubMed:28596309).  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Is able to repair glycated serum albumin, collagen, glyceraldehyde-3-phosphate dehydrogenase, and fructose biphosphate aldolase.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE) that cause irreversible damage (PubMed:25416785, PubMed:26774339).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  However, is less efficient than Hsp31 and YhbO, suggesting that YajL might be preferentially dedicated to protein repair (PubMed:28596309).  Displays a covalent chaperone activity with sulfenylated thiol proteins by forming mixed disulfides with members of the thiol proteome, and preferentially with sulfenylated cellular proteins, upon oxidative stress; these mixed disulfides can be subsequently reduced by low-molecular-weight thiols to regenerate YajL and reduced proteins (PubMed:22157000, PubMed:22321799).  Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone (PubMed:20889753).  Confers resistance to oxidative stress (PubMed:20124404, PubMed:22157000, PubMed:22321799).  Plays an important role in protection against electrophile/carbonyl stress (PubMed:26774339).  The chaperone activity reported for YajL is probably recruited to execute its deglycase activity, to interact with non-native glycated proteins and gain access to partially buried glycated sites (PubMed:25416785, PubMed:26774339).  Also displays an apparent glyoxalase activity that in fact reflects its deglycase activity (PubMed:26774339, PubMed:26678554).
What are the official names of this protein?
Protein/nucleic acid deglycase 3, Chaperone protein YajL, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: RS20_BORGP
Sequence: MRKNASALKRSRQNLKRKIRNVSVESELKTIEKRCINMIKAGRKDEAIEFFKFVAKKLDTAARKRIIHKNKAARKKSRLNILLLK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PROB_XANC8
Sequence: MLKVGSSLLAADGGGLSPRFALGLAQFVSANLAAGREVVIVSSGAVAAGRAILPKAAEAGAAIAARQALAALGQAQLIALWQRFFERPVAQVLLTHDDLRNRRRYLNARATLGELLRLGALPVINENDTVSVDELKLGDNDNLAAIVAALVDADALFIATDIDGLYSADPRSNPLARPLDEVAELSAEVLAMAGGSGSSVGTGGMRTKLEAAAKAGAAGIETYLFNGRSAEVVRGLAQDRLCGTRIHAARTRIAARKYWLRHAPVEPGTILIDAGAALALTDKGASLLPGGVAGAEGDFRRGDMVEIHLRDSVGSRCLARGVSQYSALDVRRIARRHSREIEPILGYSYGENVVHRDDLVVL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTMP_XENTR
Sequence: MPHTNEDPTAQQAGVILDPPPPLPPPPQIHLLPPTVAKCKFFKKVAENSDPSTGGCEELKKMIKNRQSRFNGELKWLLYNQYVPSLIQEGPQCGLVALWMAGKLLNLAHEAPLQTIVEAAVSRGYTAQGEMFSAANMAVLAKEVFGCRSELLTGGMDGENKGKILQQLTSGLPVLIPYDEDFNHEPCQREGHRAHWAVISGVLFGVRCGSFSPDPDIPGLCYPSSDSPSLEDLNIQEIYLVAKQGKSLRYQLWEYDCISRSNGQLIHLDPKRSNDGNVYIVPSGGVKAGLCGQIVLFQPKDV
What is the function of this protein?
Actin maturation protease that specifically mediates the cleavage of immature acetylated N-terminal actin, thereby contributing to actin maturation (By similarity).  Cleaves N-terminal acetylated methionine of immature cytoplasmic beta- and gamma-actin after translation (By similarity).  Cleaves N-terminal acetylated cysteine of muscle alpha-actin after canonical removal of N-terminal methionine (By similarity).
What are the official names of this protein?
Actin maturation protease, Actin aminopeptidase ACTMAP.
What is the protein family that this protein belongs to?
Belongs to the ACTMAP family.
Protein: RL18A_CASSA
Sequence: MVTFRFHQYQVVGRGLPSETDEHPKIYRMKLWATNEVRAKSKFWYFLRKLKKVKKSNGQMLAINEIFEKNPTKIKNYGIWLRYQSRTGYHNMYKEYRDTTLNGAVEQMYIEMASRHRVRFPCIQIIKTATIPAKLCKRESSKQFHNSKIKFPLVTRKIRPPSRKLKTHYKASRPNLFM
What are the official names of this protein?
60S ribosomal protein L18a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: MENC_ECOSE
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: SPS2_TRYB2
Sequence: MSEKEGKVIPETNGMKRPRFDPVKLGLPEEFTLTDYTRLKGCSCKVPQPELLALLQSVSTTPGRRDVGMDCSIVKLQHKDETGKPLYMVSTTDFFFPSVEDPYLQGQIGAANVLSDLYSTGIDRCDTVLMLLAASTDMDKTEREVCTQEMMKGFVDHVRLAGSDVTGGQTVMNPWPLIGGIATSVVAESQMIRPTGLQPGDILVLTKPLGCQIAVNLKQWLRRPSPIFEEQIQGKMDSEEIEELYNAAADGMKRLNRMAAALMHSHGAHGATDVTGFGILGHAKNLGSAQKADVCLVLDSLPMYRGAVKASKLMGDKYRLFEGYAAETSGGLLVAFGTREEAEGYIRELYETDGEPAWVVGRVVRREGSAPYALLQKDYKIIEVGAKVNDKII
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenophosphate synthetase 2, TbSPS2, TbselD.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: PRIB_SHISS
Sequence: MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).  During primosome assembly it facilitates the complex formation between PriA and DnaT.
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: QUEC_PHOPR
Sequence: MRKAVVVFSGGQDSTTCLIQAIKNYDEVHCITFDYGQRHKLEIEVAQSITKELGITAHKVMDVGLLNELAISSLTRDNIEVSHELQANGLPNSFVPGRNILFLTLSGIYAYQIGAEAVITGVCETDFSGYPDCRDEFVKSLNQSLVLGMDRALKIETPLMWLNKAETWALADQYKQLDFVREKTLTCYNGIIGDGCGNCPSCDLRRAGLEDYLTNKDAIMADLVAKQAEGQA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: CH60_OLEAN
Sequence: MAAKDVLFGDSARAKMLVGVNILADAVRVTLGPKGRNVVIEKSFGAPIITKDGVSVAREIELKDKFENMGAQMVKEVASQANDQAGDGTTTATVLAQAIISEGLKSVAAGMNPMDLKRGIDKATAAVVAAIKEQAQPCLDTKAIAQVGTISANADETVGRLIAEAMEKVGKEGVITVEEGKGLEDELDVVEGMQFDRGYLSPYFINNQEKMTVEMENPLILLVDKKIDNLQELLPILENVAKSGRPLLIVAEDVEGQALATLVVNNLRGTFKVAAVKAPGFGDRRKAMLQDLAILTGGQVISEELGMSLETADPSSLGTASKVVIDKENTVIVDGAGTEASVNTRVDQIRAEIESSTSDYDIEKLQERVAKLAGGVAVIKVGAGSEMEMKEKKDRVDDALHATRAAVEEGVVAGGGVALIRALSSVTVVGDNEDQNVGIALALRAMEAPIRQIAGNAGAEGSVVVDKVKSGTGSFGFNASTGEYGDMIAMGILDPAKVTRSSLQAAASIAGLMITTEAMVADAPVEEGAGGMPDMGGMGGMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_HAEDU
Sequence: MNPRRKSRLKVVVLIMFSVAVAAGLTLYALSQNIDLFYTPSEIVKGKNNDPQLKPAVGQRIRVGGMVVEGSVKRDDKTLKVEFNLNDIGPAITVEYEGILPDLFREGQGIVAQGVLVEPTRLKASEVLAKHDENYMPPELGDKMKQQHNAVGVAEGDLKGESIRDKAELDRTFNTLQGESK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: ANMK_ECO45
Sequence: MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGHGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGGRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: DADA_YERPS
Sequence: MRVVILGSGVVGVTSAWYLAKEGHDVTVIDRQDGPAQETSAGNAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAIRLDGSSLQLRWMWQMLRNCDTSHYMVNKSRMVRLAEYSRDCLKDLRAATGIQYEGRQGGTLQLFRTEQQFDNAAKDIAVLDDAGVPYSLLTAEQLATVEPALAKVAHKLTGGLRLPNDETGDCKLFTERLAKMAEQAGVKFIFNRSVDKLLVEGDQIAGVLCGDDIIKADAYVVAFGAYSTALLAGLVSIPVYPLKGYSLTIPITDPASAPFSTVLDETYKIAITRFDDRIRVGGMAEIVGFNTQLAPARRETLEMVVRDLYPHGGDISQAVFWSGLRPMTPDGTPIVGRTPLKNLYLNTGHGTLGWTMACGSGQLLADIIQGRRPAIVADDLSVARYRAGFQPLNIAPLHDIHPIR
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: RNR_VIBPA
Sequence: MSDNIPNDPFADRESQNYENPIPSREFILEFLEQAGVPMNRNDLFEALKLAGEEQYEGLRRRLRAMERDGQLVFTRRQCYALPEKLEMVKGYVIGHKDGHGWVRPEGSVGKDDDILLPHHQMKNIIHGDFVLVQPTDNSKRGRREGRLVRVLEERNSQIVGRFFLEYGYSYVVPDDSRISQDILIPNEHKAGARMGNVVVIEITDRGSRSRGMMGKVVEVLGENMAPGMETQIAIRTHQIPYEWPEAVEKQIVNLGEEVPEEAKVGRVDLRELPLVTIDGEDARDFDDAVFCEKKKDGGWRLWVAIADVSYYVRPDSALDKEAINRGNSVYFPSQVVPMLPEVLSNGLCSLNPQVDRLCMVCEMTISESGKLSSYKHYEAVMNSHARLTYSKVSAILEGDEELRERYQPLVSHLEELHAMYKVLKEARDQRGAIEFETVETKFIFNAERKIESIEPVIRNDAHKIIEECMILANIASASLVEKAKEPALYRIHESPGELRLQGFRDFLSELGLELKGGLEPSPTDYADLARQIAGRQDQELIQTMLLRSMKQAVYNADNAGHFGLALKRYAHFTSPIRRYPDLLLHRAIKYLIAKEEGRNQDRWTPTGGYHYSFDDMDFYGEQCSMTERRADDATREVADWLKCEYMQDHVGDELEGVIANVTSFGFFVRLTDLHIDGLVHISTLANDYYQFDPIGQRLIGESFGNIYRLGDAVKVKVLAVNLDDKQIDFELVETSRKLRGEGKTAKKRAAEAKRKAKEKKRAATRSSSKESATARAVPAIEPTKRPEQTDSGRKRKGPKRGDDDSAKKPKVKKAHKKKPHSKPKKTKRTKQDAQ
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
What are the official names of this protein?
Ribonuclease R, RNase R, VacB protein homolog.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_CALS4
Sequence: MDREEARKRIEELREKINYHNYRYYVLDQPEISDYEYDMLMRELIELEEKYPEFKTPDSPSQRVGGEPLDEFEPFTHIVPMLSLANAFTAEEIKEFDRRVKEAVGEVEYVVEPKIDGLSVELVYENGMFTVGSTRGDGIVGENVTPNLKTIKSIPLRLKDSVNLVVRGEVFMPKASFAKLNEERAERGESLFANPRNAAAGSVRQLDPKVTAKRDLDIFIFNLQRIEGRDFKTHVEALEFLKEQGFKVIPLIKKCTTIEEVIKAIEELGEMKDSLPYDIDGAVIKVNELDKREILGQTAKDYRWAIAFKYPAEMKKTKIVDIVVQVGRTGALTPTAVLEPVVISGSVVSRATLHNEDYIKEKDIRIGDTVLVHKAGGIIPEVVEVVKEERTGDEKAFVMPDKCPECGALAVRLPGEAVRRCTGLNCPAQIARRIIHFASKDAMDIEGLGPAIISQLLSKGLIQNVADLYYLKYRDLITLERMGDKSARNLLEAIEKSKKRDLDRLLFGLGINLIGSKAAQVIAEHFKSMDNIMKAKYEDFLELPDIGPKMARSIVTFFSEEQNRRVVERLKEAGVNMEKLSTGKVSNIFEGKIFVLTGALKNYTRDEAARLIVERGGKVTNSVSKKTDYLIVGADPGSKLKKAQELGVKIINEEQFEAMLKGDIQP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MENH_ENT38
Sequence: MILNGKTRAGKPGFPWLVFLHGFSGDSREWQDVGAQLPDYPQLHLDLPGHGDSANIAVAGFDEVSQLLADTLVSYNILKFWLVGYSLGGRIAMFHACQHPAGLIGLIVEGGHPGLHDEPTRKARAESDAQWAERFRREPLENVFSAWYQQPVFAALQETERDALVALRSQNNGAALGAMLQATSLAQQPDLRAALRAHDYPFHYVYGEHDDKFGAIATELTAQRHVIPNAGHNAHRENPAAVAACLAQILRLRIKDIP
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: CSPL9_SOYBN
Sequence: MASENGDKLELAFSAVPDPKPKKDWVILSLRVVAFFATASATLVMAFNKQTKGMVVATIGTNPVTITLTAMFQHTPAFIFFVIVNAIASFYNLLVIGVEILGPQYDYKGLRLGLIAILDVMTMALAATGDGAATFMAELGRNGNSHARWDKICDKFEAYCNRGGVALVASFVGLILLLVVTVMSITKLLKLNRI
What are the official names of this protein?
CASP-like protein 1B1, GmCASPL1B1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS12_MYCPA
Sequence: MPTIQQLVRKGRRDKIGKVKTAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL24_DEBHA
Sequence: MKVELDSFSGTKIYPGRGTLFVRGDSKIFRFQSSKSASLFHQRKNPRRISWTVLYRRQHKKGISEESAKRRTRKTVKNQRAIVGASLELIKERRSQKPSDRKAARDVKLAKDKEAKKADKAARKAEKAKSAAAGAQSKVSKQQSKGAFQKVHATSR
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: RNH3_STRPQ
Sequence: MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPDPLTFQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIP2_HORVU
Sequence: AAKMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNEPVLPPVEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTPGLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLEDAVTALHGRTKADKASGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKAVEKKSGKIGNEMKAQVNGWQDLSAALLKTDVKPPPGKSPAKFTPIEKMGVRTAEQAAATLGILLFVEVPGGLTVAKALELFHASGGK
What is the function of this protein?
Inhibits the elongation phase of protein synthesis.  It inactivates fungal ribosomes even more effectively than mammalian ribosomes and is thought to function as a constitutive antifungal agent in plants.
What are the official names of this protein?
Protein synthesis inhibitor II, Ribosome-inactivating protein II, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Starchy endosperm of mature seeds.
Protein: RSMJ_SHEPA
Sequence: MTSIFFNRHYPTIESACERWGLVYDPDAEFELVFEDNILTLIKRDEPKLKGISVDFVSGAVAHRRKFGGGRGQSIAKAVGLKQGVMPTVVDGTAGLGRDAFVLASLGCKVLMVERHPIVAALLEDGLRRAYEDAEIGGWMQQRMSLFHGSSIDSLADAAKASNTEVDVVYLDPMYPHREKSALVKKEMRVFQSLVGADLDADGLLAPAMALATKRVVVKRPDYADDLDGVKPSMVIATKKNRFDVYVKAAMTA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_CHLPN
Sequence: MSRSLRKGPFVDHHLLKKVRAMNIEEKKTPIKTWSRRSMITPEMIGHTFEVHNGKKFLTVFVSETMVGHKLGEFSPTRIFKSHPVKKG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GLYA2_BURP1
Sequence: MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRYYGGCEFADEVEALAIERVKRLFNAGHANVQPHSGAQANGAVMLALAKPGDTVLGMSLDAGGHLTHGAKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHKPSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRGPRGGFVLTNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLILEVFEALRTNPEGDHATEQRVRREIFALCERFPIY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 2, SHMT 2, Serine methylase 2.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASTA_VESAN
Sequence: IKWKAILDAVKKVL
What is the function of this protein?
Chemotactic peptide for polymorphonucleated leukocytes (PMNL), but causing no hemolysis to erythrocytes and no mast cell degranulation activity at physiological concentrations.  Potent antimicrobial peptide against both Gram-positive and Gram-negative bacteria (By similarity).
What are the official names of this protein?
Mastoparan-A.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Mastoparan subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CS4F1_GEOSL
Sequence: MAETDGSIPLIPVRMLNEHVYCPRLAYLMWVQGEFSHNEFTVDGVIRHRRVDAGGGVLPSETQEDSRIHARSVSLSSERLGITAKIDLVEGEGAYVSPVDYKRGKRPHVAGGAYEPERVQLCAQGLLLREHGFASDGGALYFVASRERVPVAFDDELIGRTLAAIDEMGRTALSGTMPPPLEDSPKCPRCSLVGICLPDEVRFLSHLSVEPRPIIPADGRGLPLYVQSPKAYVRKDGDCLVIEEERVRVAEARLGETSQVALFGNATLTTAALHECLRREIPVTWLSYGGWFMGHTVSTGHRNVETRTYQYQRSFDPETCLNLARRWIVAKIANCRTLLRRNWRGEGDEAKAPPGLLMSLQDDMRHAMRAPSLEVLLGIEGASAGRYFQHFSRMLRGGDGEGMGFDFTTRNRRPPKDPVNALLSFAYAMLTREWTVALAAVGLDPYRGFYHQPRFGRPALALDMMEPFRPLIADSTVLMAINNGEIRTGDFVRSAGGCNLTDSARKRFIAGFERRMEQEVTHPIFKYTISYRRLLEVQARLLTRYLSGEIPAYPNFVTR
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).  The Cas4 region acts as a ssDNA exonuclease, while the Cas1 region acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
What are the official names of this protein?
CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: MGSA_VIBVU
Sequence: MQKTTRTMPAHKHIALVAHDNYKPELLRWVKENKEKLQSHFLYATGTTGHMLSRETGLAIKSMISGPMGGDQQLGALISEGKIDMLIFFWDPLNAVPHDPDVKALLRIASVWNIPVATNRATAKFLFESPLLNEEVDVEIPDYQAYLAGRT
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RECR_THEFY
Sequence: MYEGAVQNLIDELGRLPGVGPKSAQRIAFHLLAAETADVHRLVNALVAVKERVRFCAVCGNIAEETQCRICRDPRRDDTVICVVEEPKDVVAIERTREFRGRYHVLGGAISPIEGVGPDDLRVKELMARLSEGRVTEVILATDPNLEGEATATYLARLLKPMGLKVTRLASGLPVGGDLEYADEVTLGRAFEGRRALDF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.