PharMolix/UniProtQA huggingface dataset:
Protein: EUTC_XANAC
Sequence: MSVPSTPPRDAWAQLRQLTPARIALGRVGTSLPTDAHLEFQLAHAQARDAVHLAFDPAPLQAALEQRGRSNILLQSAAADRHQYLQRPDLGRRLAEEAAAQLRGLTAVHGGRHDVAVVVADGLSALAVHRHAARMLDQIDALASQEGWSLAPVVLVRQGRVAIGDEVGELLDARTVIVLIGERPGLSSPDSLGLYLTYTPRVGLTDAARNCISNIRAEGLSYAEATHKLGYLLREAFRRKLSGVQLKDEAEQPALLSGPADVAPRTFLLPD
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: THIC_ANADF
Sequence: MRAQWIARRHGQPNVTQMHHARRGSVTEEMAHVAAREKLDPELVRQEVARGRMVIPANLKHPELEPIAIGIAATCKINANIGNSAVTSDVDEELRKLSVCLRHGADTVMDLSTGGDIPLIRENILRHSPIPVGTVPIYECLAHVKDVVDLTPRGLLEIIEAQAAQGVDYMTIHAGVLRDIVPMAAGRITGIVSRGGALLARWMAANGQENPLYTHFDEICEIFKRYDVTFSLGDGLRPGCLADASDEAQFAELKVLGELTRKAWAHDVQVMVEGPGHVPLDQIPMNMQKERELCDEAPFYVLGPLVTDIAPGYDHITSAIGAAVAAQHGASMLCYVTPAEHLGLPDAEDVRQGIVAYKIAAHAADVARQRPGARDRDDALSRARYAFDWKRQFELSLDPDAARTKHDATLPQEAAKSAEFCSMCGPKFCSMRIHSHLGDGAAPGAALPCADAAPSQPTRAGGPLPIAR
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: Y1245_TRIL1
Sequence: MSGHNKWSTIKHKKGAADAKRGKIFTKIIKEISVAAKLGGGDPAANPRLRTAIDKAKGENMPKDNIERAIKKGTGGMEGVVYEEIVYEGYGPGGVAVLVEVMTDNRNRTVSEVRSIFTKCNGNMGEAGCVAWMFDKKGVISYDTSLDFDQLFEAALEAGAEDVVEEDEQIEVYTEPSSFIEVRDALEAKGFKFQSAEITMIPQTQVALEGKQAESMLKMMDRLEDCDDVQNVYANFDISADEMEKMM
What are the official names of this protein?
Probable transcriptional regulatory protein Glov_1245.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAZF1_MYCTU
Sequence: MLRGEIWQVDLDPARGSAANMRRPAVIVSNDRANAAAIRLDRGVVPVVPVTSNTEKVPIPGVVAGSERWPGRRFEGAGPAGWIRRCATSPLPS
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system, its cognate antitoxin is MazE1 (Probable).  Probably an endoribonuclease (By similarity).
What are the official names of this protein?
Probable endoribonuclease MazF1, Probable toxin MazF1.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: S1FA_MAIZE
Sequence: NKGLNPGMVVXLVVASFLLIFFVGNYALYXYAQKTLPPKKKKPVSKKKLKKEKLKQGVSAPGE
What is the function of this protein?
DNA-binding protein that specifically recognizes a negative element (S1F) within the RPS1 promoter.
What are the official names of this protein?
DNA-binding protein S1FA.
What is the protein family that this protein belongs to?
Belongs to the S1FA transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y4370_ARATH
Sequence: MAVEYVCCSPNFFIHIAVIVFLVLFAGLMSGLTLGLMSLSLVDLEVLAKSGTPEHRKYAAKILPVVKNQHLLLVTLLICNAAAMETLPIFLDGLVTAWGAILISVTLILLFGEIIPQSICSRYGLAIGATVAPFVRVLVFICLPVAWPISKLLDFLLGHRRAALFRRAELKTLVDFHGNEAGKGGELTHDETTIIAGALELSEKMVKDAMTPISDIFVIDINAKLDRDLMNLILEKGHSRVPVYYEQPTNIIGLVLVKNLLTINPDEEIPVKNVTIRRIPRVPEILPLYDILNEFQKGLSHMAVVVRQCDKIHPLPSKNGSVKEARVDVDSEGTPTPQERMLRTKRSLQKWKSFPNRASSFKGGSKSKKWSKDNDADILQLNGNPLPKLAEEEEAVGIITMEDVIEELLQEEIFDETDHHFEDS
What are the official names of this protein?
DUF21 domain-containing protein At4g33700, CBS domain-containing protein CBSDUF6.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS12_SALEP
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: P3_BPPH6
Sequence: MRYQGINEWLGGAKKLTTANGEIGAIYLSAAPPTDAARADAKAVDFTAGWPSAIVDCADATRAKQNYLWVGDNVVHIGAKHVPLLDLWGGTGDAWQQFVGYACPMLDLCRAWGLGYASASVTTGSLQGYQPSAFLDVEQQQFAKDNLNLYGDNCLDLATSSSAQRAFLEQCMGCALPEDCIFGWYVKMDWEGSAVADAYAAIRVQGFATVMAPWQSVGGAGYVYARVPQKGAWMGVNLLAYVHGTSGQPAYGIPMTLSGFTGNMGQVASKWLMLPLLMIVDPHVVQILAALGVKRGTKSDPRTTDVYADPKVPASRISGPMINGTVAPPATIPATIPVPLAPLGGAGGPGAQGFQVYPVFTWGLPEFMTDVTIEGTVTADSNGLHVVDDVRNYVWNGTALAAIEQVNAADGRVTLTDSERAQLASLTVRTASLRQQLSVGADPLSKTSIWRRAQKADYDLLSQQIIEADTVKNLPAVTFAQANKAAGGQSETLWHQMYRVNDIAGDQVTAIQITGTMATGIRWSATAGGLVVDADEQDAVIAISSGKPVKNSSDLPTADAVNYLFGITADDMPGIVSSQKEMNSEFEEGFLQKARLWNPRKLVENVQNAYFLMVYARDRKQFHSLVASSLAMAKLGVSTRACKESYGC
What is the function of this protein?
P3 protein is necessary for adsorption onto host cells.  Attaches to a type IV pilus of the host.
What are the official names of this protein?
Spike protein P3.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Note=The spike protein P3 protrudes from the membrane, where it is anchored by the integral membrane protein P6.
Protein: LIPB_MYCLB
Sequence: MDSIRSIPTAIDVRQLGTVDYHIAWQLQRDLADARVAGGPDTLLLLQHPPVYTAGRRTQPHERPNPSLHGVPVVETDRGGKITWHGPGQLVGYPIIGLAEPLDVVNYVRRLEEALIKVCAELGLDTSRVNGRSGIWVPGSAGQPARKIAAIGVRVSRATTMHGFALNCQCDLDAFHAIVPCGISDAGVTSLSAELGRTVAVNDVRSAIAEAVNDALDGWLALSWLSTPASVTSTL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B2_ORYSI
Sequence: MAPKAEKKPAEKKPAEEKAGEKAPAAGKKPKAEKRLPASKGEKGGEGKKERGRKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAGEAAKLARYNKKPTITSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TRPD_YERPS
Sequence: MQHLFEKLFRAESMSQEESQQLFAAIVRGELEPSQLAAVLISMKVRGETPAEIAGAAQALLADAQHFPRPDYLFADIVGTGGDGTNSINISTASAFVAASCGVKVAKHGNRSVSSRSGSSDLLAAFGIRLDMSAEQSRLALDDLGVCFLFAPQYHTGFRHAMPVRQQLKTRTLFNVLGPLINPARPPLALIGVYSPELVLPIAQTLKVLGYQRAAVVHGGGMDEVAIHAPTQVAELNNGSIESYQLTPEDFGLNRYPLAALQGGMPEENRDILARLLQGKGETAHAAAVAANVALLLKLYGQENLRHNAQQALEMIHSGQAFDRVTALAARG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: TRMFO_STRPD
Sequence: MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDREGYAESVTAELENHPLIEVIRDEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGFYFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQDNTAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLTETFQSRRNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGSLPHYVTHADSKHFQPMNVNFGIIKELEGLRIRDKKERYEAIASRALADLDTCLASL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_DESAL
Sequence: MTSQDALKKQAAEKAVEYLESGMVVGLGSGSTATFAIHAIARLMKEGKLKDIVGIPSSTPTEEVARSLGIPLVGFEEHAVIDVTIDGADEVDPDLNLIKGGGGALLREKVVAQATKKNIIIVDESKISDKLGTIFALPVEVVPFATASETRFLESLGAKVTVRENQLGKAFKTDNHNRILDADFGPMDDAVKIGMALSQRAGVVEHGLFLGTTALVIVAGADGIREMKAA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RS12_ECO7I
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: HUTH_PARDP
Sequence: MSELILIPGETTLAQLEQVWRQGLAVRLADSARPGIAESAARIAAAANGEAPVYGVNTGFGKLASIKIAARDTATLQRNLILSHCCGVGEPVEPETVRLIMVLKLLSLGRGASGVRPEVIQLIEDMLARGVLPVIPSQGSVGASGDLAPLAHMAAAMLGEGRAVHEGREMSSAEALASAGLKPVVLAAKEGLALINGTQVSTAFALAGLFEAFASARAALVTSSLSTDAIMGSTAPFLDEIHTLRGHRGQIVAARTIRALMDGSEIRESHREGDSRVQDPYCIRCQPQVTGACIDLLWQAARTLEIESNAATDNPLVLVGADRIVSGGNFHAEPVAFAADQIALAIAEIGAISQRRIALMVDPALSHDLPPFLTPDPGLNSGLMIAEVTSAALMSENKHLATPCSTDSTPTSANQEDHVSMAAHGARRLKRMNANLAQILGIEALCASAGVEFRAPLATSAPLQAVIAALRQTVPALEQDRYLAPDLAESARLVREGVLVGAIPSHLLDEVRP
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_MYCBO
Sequence: MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRVSGVPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACOI_PIG
Sequence: MKRRNADCSKLRRPLKRNRITEGIYGSTFLYLKFLVVWALVLLADFVLEFRFEYLWPFWLFIRSVYDSFRYQGLAFSVFFVCVAFTSNIICLLFIPIQWLFFAASTYVWVQYVWHTERGVCLPTVSLWILFVYIEAAIRFKDLKNFHVDLCRPFAAHCIGYPVVTLGFGFKSYVSYKMRLRKQKEVQKENEFYMQLLQQALPPEQQMLQKQEKEAEEAAKGLPDMDSSILIHHNGGIPANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKRLNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCTSKSPSAHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTETLRNRIRELEAEGKKLTMDMKVKEDQIRELELKVQELRKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQILQKDQEIKDLKQKIAEVMAVMPSITYSAATSPLSPVSPHYSSKFVETSPSGLDPNASVYQPLKK
What is the function of this protein?
Plays a role in the regulation of neuronal activity.
What are the official names of this protein?
Macoilin, Macoilin-1, Transmembrane protein 57.
What is the protein family that this protein belongs to?
Belongs to the macoilin family.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi- pass membrane protein. Note=Detected in the nucleus membrane of non-neuronal cells and in axonal outgrowths of neuronal cells.
Protein: HSL54_DICDI
Sequence: MTILSAITSISRPNKISKSVISSNGGSSLSMGSNSVSCYNACGGGSSYSYSSSYSGSGLDYSYKANYSSSTGYNSSVVIASSTCHCS
What are the official names of this protein?
HssA/B-like protein 54.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: NUOD_BORBR
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAEHKTFIQALPYMDRLDYVSMMCNEHAYVMAIEKLLGIEAPLRAQYIRVMFDEITRVLNHLMSLGSHALDVGAMAVFLYAFREREDLMDCYEAVSGARMHAAYYRPGGVYRDLPDTMPQYGDSSKYRGEKEVRAMNDARSGSLLDFIEDFTNRFPGCVDEYETLLTDNRIWKQRLVGIGVVDPDRAKALGFTGPMLRGSGVAWDLRKTQPYEVYDLMDFDVPVGVNGDCYDRYLVRVAEMRESNRIIRQCVEWLRNNPGPVMIENHKIAPPSRTAMKSNMEELIHHFKLFSEGFHVPPGEAYAAVEHPKGEFGIYLVADGANKPYRLKIRAPGFAHLQSLDEMARGHMIADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UGDH_CHICK
Sequence: MFEIKKICCIGAGYVGGPTCSVIAQMCPKIQVTVVDVNEARINAWNSDTLPIYEPGLKEVVESCRGRNLFFSTSIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLDLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDDSPEGQKAVRALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVARAIGTDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAKLHIYDPKVPKEQIILDLSHPGVSEDNQVSRLVTISQDPYEACDGAHALVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDDLHNELQVIGFQIETIGKKVSAKRIPFASSCEIPKFSLQDPPVKKPRV
What is the function of this protein?
Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans (By similarity).  Required for the biosynthesis of chondroitin sulfate and heparan sulfate.  Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity).
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: YIDD_CORJK
Sequence: MARRLILGYQSYLSPLKMGPTCRFEPTCSNYALIAISRHGLIKGSVLALGRLARCGPWHPGGWDPVPPRRPLCSWGGRRR
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CCA_BORPE
Sequence: MSRTDDPGVAGLRVYIVGGAVRDDLLGLPAGDRDWVVVGATPEDMARRGFIPVGGDFPVFLHPRTKEEYALARTERKSGRGYKGFTFYTGADVTLEQDLQRRDLTVNAIARTPQGELVDPLDGVADVRARVLRHVGEAFAEDPVRILRLGRFAARFGDFSIAPETMQLCRRMVEAGEADALVPERVWKEVSRGLMAQAPSRMLDVLARAGALARVMPELHDDTAVRAEIDRAAAAGLPLAGRYALLCRHTPERDALGRRLRAPVECMDQARLLPLAVDALAASATPAAQLDLIERCDALRKPERFDALLQAAAIVAPVDLSAWRARVQAVRAIDAGAIARQCAGDPARIKPALRQARLQALGGA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
Protein: FADE_ECO57
Sequence: MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLKEHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVPFQNGPTLGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNVFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLRSINVDDFDPEELATKPVKLPEKVRKVEAA
What is the function of this protein?
Catalyzes the dehydrogenation of acyl-coenzymes A (acyl-CoAs) to 2-enoyl-CoAs, the first step of the beta-oxidation cycle of fatty acid degradation.  Is required for the utilization of medium- and long-chain fatty acids as sole carbon sources for growth.
What are the official names of this protein?
Acyl-coenzyme A dehydrogenase, ACDH, Acyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: RL31_CARHZ
Sequence: MKPGIHPEYGKARVICACGETFETGSTKKEIRVEICSKCHPFYTGSQRTVEARGRAEQFKKKYGL
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RS2_MANSM
Sequence: MAQVSMRDMLQAGVHFGHQTRYWNPKMKPFIYGPRNGVHIINLEKTVPMFNGALAELTRIASNNGKILFVGTKRAATEAVQAAALDCQQYYVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALVRTREMEKLELSLGGIKDMAGLPDAIFVIGADYEHIAIKEANNLGIPVFAVVDTNSNPDGIDFVIPGNDDATRAIQLYVTAAAAAVKEGRSQQTATEEKFAEEVAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ILVD_SYNS9
Sequence: MLRSDAVTKGIQRSPNRAMLRAVGFGDADFGKPILGIANGYSTITPCNIGLDVLAKRAEEAARLAGGMPQMFGTITVSDGISMGTEGMKYSLVSREVIADAIETACNGQSMDGVLAVGGCDKNMPGAMLAMARMNIPSVFVYGGTIKPGKLGGCDLTVVSAFEAVGQITSGKIDEEQLTAVEKNACPGAGSCGGMFTANTMSAAIETMGLSLPYSSTMAAEDQEKADSAARSAEVLVDAVKANIRPLDLLTTEAFENAISVIMAVGGSTNAVLHLLAIARTAGVDLSIDDFERIRQRVPVICDLKPSGRFVTVDLHNAGGIPQVMKLLLDAGLLHGDCQTVEGKSLNELLADVPSEPPADQEVIRPLTNPMYSKGHLAILKGNLAIEGSVAKISGVKTPVLTGPARVFESEEDCLASILEKKINAGDVVVIRYEGPVGGPGMREMLAPTSAIVGQGLGDKVALITDGRFSGGTYGLVVGHVAPEAAVGGTIGLVQEGDSITVDANQLLLQLNVDETELAKRRAAWSKPKPRYTTGILGKYARLVSTSSKGAVTDQPD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RS11_ECOUT
Sequence: MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SYR_BURM9
Sequence: MLPAQKHTLETLLENSVKQVVQASKGDADAAFVLPAIALERPKVAAHGDVACNVALQLAKPLGANPRQLAEQIVAALTAQPEAAGLVDAAEIAGPGFINLRLTPASKQAVIGAVLAQGRAFGASERDHDKRVLLEFVSANPTGPLHVGHGRQAALGDALANVLASQGYAVHREFYYNDAGVQIGNLAISTQARARGLKPGDAGWPEAAYNGEYIADIARDYLNGETVAASDGEPVTGKRDVEDLEAIRKFAVTYLRREQDMDLKAFGVKFDQYYLESSLYTEGRVEKTVDALIAAGMTYEQEGALWLRTTDEGDDKDRVMRKTDGTYTYFVPDVAYHVTKWERGFTKVINIQGSDHHGTIARVRAGLQGLHIGIPKGYPDYVLHKMVTVMRDGQEVKISKRAGSYVTVRDLIEWSGGATPGSEGSPELLDEATITRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVYYVQYAHARICSVINEWKSRYGATDALLPGADLSPLDSKQAMALMQKLAEYPDVLAHAAGELAPHAVAFYLRELASEFHSFYNAERVLVDEQAPRTARVALLAATRQVLENGLAMLGVSAPSKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_DESVM
Sequence: MGQKVHPYGFRLGYNKNWQSRWFSKKEYPGFVFEDHNIRKFVKKTLYHAGLSKIEIERAGGKVRLILSTARPGIVIGRKGVEIEKLRGDLRKKFKREFSIEVNEIRRPEVEAQLVAENIALQLERRVAFRRAMKRTVSMSRKFGAEGIKVTCSGRLAGAEIARTEWYRDGRVPLQTLRADIDFGFAEARTTYGVIGVKVWIFKGEILDNEVEQ
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL30_NITHX
Sequence: MAKAAKTIKVEQTRSAIRRQHSQRSTLVGLKLNKIGRVAELQDTPETRGMIAKVQHLVRVIDET
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: IKBD_HUMAN
Sequence: MEAGPWRVSAPPSGPPQFPAVVPGPSLEVARAHMLALGPQQLLAQDEEGDTLLHLFAARGLRWAAYAAAEVLQVYRRLDIREHKGKTPLLVAAAANQPLIVEDLLNLGAEPNAADHQGRSVLHVAATYGLPGVLLAVLNSGVQVDLEARDFEGLTPLHTAILALNVAMRPSDLCPRVLSTQARDRLDCVHMLLQMGANHTSQEIKSNKTVLHLAVQAANPTLVQLLLELPRGDLRTFVNMKAHGNTALHMAAALPPGPAQEAIVRHLLAAGADPTLRNLENEQPVHLLRPGPGPEGLRQLLKRSRVAPPGLSS
What is the function of this protein?
Regulates the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity.  Functions in the regulation of inflammatory responses.  Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR).  May also regulate TCR-induced negative selection of thymocytes.
What are the official names of this protein?
NF-kappa-B inhibitor delta, NFKB inhibitor delta, I-kappa-B-delta, IkB-delta, IkappaBdelta, IkappaBNS, T-cell activation NFKB-like protein, TA-NFKBH.
What is the protein family that this protein belongs to?
Belongs to the NF-kappa-B inhibitor family.
What are the subcellular locations of this protein?
Nucleus.