PharMolix/UniProtQA huggingface dataset:
Protein: TGT_STRZT
Sequence: MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSIGGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIRLTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PYRF_METAC
Sequence: MERNTCMILALDVTDREEALKIAEDVWEFVDAIKVGYPLILATGLGIIRELAEFAPVIADFKVADIPNTNRLICDQVFEAGADAVIAQGFTGRDSLDACIEIASEYRKDVFVVSEMSHPGGADFMQPVAEAIAKMALEAGAFGLVAPATRPKRVKKIRRIIGDKLTIISPGVGAQGGKASDVIAAGADWVIVGRSIYKAESPKEAARQIAEEIQAELRGEY
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: Y1541_CLOBK
Sequence: MDNNFKIKDLPKNERPQERLIRYGAEVLSNSELLAVILRTGTKNQNIMMLASSLIKETGGLDQLFNQSIEELTKIKGIGVTKAVQILALSELSKRFKTYKSGNEYKINTPLDVSNLVMEDMKYLKQEKLKILILNTKNIVTYIRDVFIGTLNSSIVHPREIFCEAIKKNGASIIICHNHPSGDPTPSKEDINITLRLKECGKLIGIDLLDHIIIGENKYVSMKEKGTI
What are the official names of this protein?
UPF0758 protein CLD_1541.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: OSM11_CAEEL
Sequence: MNFITVAALAIVMVLAQANPARVRRNEEMSERYCIKHLDHYNKYCGDNAGPIDRALFGKVAKFCPAYEKHCAVGKAGLVELPDLGSPLVMPPVLPRGSDFASLDLPIADERKPAHIHSSRTAPQTTRLTAAIVATCTPECTAAHCTDECKCAHTHPKVHQMCNPPSSAAMAETCQRWYSKCTMFTPVQY
What is the function of this protein?
Probable secreted lin-12/Notch ligand or co-ligand involved in the mediation of Notch signaling (PubMed:18700817, PubMed:21549604).  Involved in the lin-12/Notch pathway signaling of cell fate in vulval precursor cells (VPCs), acting redundantly with dsl-1 and lag-2 (PubMed:18700817).  Required for normal octanol avoidance response, acting via both lin-12/Notch and glp-1/Notch signaling pathways in neurons, in concert with lag-2 (PubMed:21549604).  Involved in regulation of sleep-like quiescence during the larval to adult transition, acting via Notch receptor activation and in parallel with EGF signaling (PubMed:21549604).
What are the official names of this protein?
Notch ligand osm-11, Osmotic avoidance abnormal protein 11.
What are the subcellular locations of this protein?
Apical cell membrane; Peripheral membrane protein. Note=Concentrated on the apical surface of vulval precursor cells.
Protein: HEM1_ACIBS
Sequence: MSFFALGVNHQTASVELREQIAFNAERLSNLLAEQRHHESLKDLVVVSTCNRTEVYAMAEDAESLLKWLADANNIDVKQLIHHVYRYENAQAITHLMRVASGLDSLMLGEPQILGQVKSALALSKEAQTVSPELNSVFEYAFYAAKRVRSETAVGSHAVSMGYAVAQLALQVFSKPEKLTVMVVAAGEMNSLVAKHLAEMGVAKMIICNRSRERADQLAQEIAHQVEVEIIDFSDLAENLYRADVVSSCTGSLHQVIAYADVKTALKKRRYQQMLMVDLAVPRDIDPKVESLDGVYLYGVDDLQSVIDENLAQRRQAAVEAEVMVNQLATQLITHQKVKEAGSTIHAYRQHSEEISQRELTHALEALHHGGNPEQVLQQFAHRLTQKLIHPTSMLLREAAKAESPDYFEWLQQHLQDVFDHERKPKR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: DAPB_MAGMM
Sequence: MTIKVGVTGVCGRMGRMLVEATHKAQGCMLGAASEYPGHTLIGADAGELAGVGKLGVLVGGDAETTFRDADVVIDFSVVEATLAHLRLALAQGTPIVIGTTGFSAAERQQIALAAERIPVVFAPNYAVGVNLLFKIAAEVAAVLGGEYDIEIVEAHHRHKVDAPSGTALGLGQAIAEAVERNLDEVAIYGRQGQTGARDPQTIGFSTIRGGDVVGDHTAMFMTDGERLELTHRASSRMTFAKGAVRAAKWVVEQKPGLYDMRDILGFK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADH_SACS2
Sequence: MRAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVKLPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLCDSPRWLGINFDGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGITTYRAVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGADYVINASMQDPLAEIRRITESKGVDAVIDLNNSEKTLSVYPKALAKQGKYVMVGLFGADLHYHAPLITLSEIQFVGSLVGNQSDFLGIMRLAEAGKVKPMITKTMKLEEANEAIDNLENFKAIGRQVLIP
What are the official names of this protein?
NAD-dependent alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: GSTA2_DICDI
Sequence: MSTSSVPSLTYFQGRGLGQFSRVLLSYLGIPYENITVTEISDALRATLPYGQLPIYRDGDFVLTQSSTIARYIAKKHNFMGKNLEEEFLVDQIVTAIHADIFPAFNNPVPEKLQKLYEKYFGSFEKKLQETGFLVGSSVTLADLYVYVGFDYIRFRGEAALSSELSDEKYPKIAELKKFFESNEGVAKYIKERPETKF
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Putative glutathione S-transferase alpha-2, GST class-alpha 2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
Protein: PNP_SHEPW
Sequence: MNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKAEEPGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSESETLIARLIDRPIRPLFPNGFKNEVQVIITVVSVDPEINPDIISMIGTSAALAISGLPFNGPLGVARVGYTNGEYVLNPDVTQLVDSELDLVVAGTEGAVLMVESEAASLPEEVMLGGVVYGHEQQQVVINAISELKAEASKPAWDWTAPVQDQELVAKIKDLAEAGLTEAYQIEVKQDRYTQVGVIKSAAKEALLAENPEADLREIDGLLGSLEKKVVRSRIIAGNPRIDGREPDMVRALNVMAGVLPRTHGSSLFTRGETQALVTCTLGTERDAQKVDSIMGEYTNRFMLHYNFPPYSVGETGFVGSPKRREIGHGKLAWRGINAVMPSAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTRDGITALQMDIKIEGITKDIMQIALQQAYGARVHILNVMDQAIGSHREDISDHAPRITTLKINPEKIRDVIGKGGATIRALTEETGTTIELEDDGTVKIASSNGEATKEAIRRIEEITAEVEVGTVYNGKVVRIVDFGAFVTILPGKDGLVHISQIAEERVANVSDYLEVGQEVKVKVMEVDRQGRVRLSMKEAAPKAEAPAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBT33_ARATH
Sequence: MRSFRSSILLVLLSLITVLNATRARSETESKVHIVYLGEKKHHDPEFVTESHHQMLASLLGSKKDADDSMVYSYRHGFSGFAAKLTKSQAKKIADLPEVVHVIPDGFHELATTRTWEYLGLSSANPKNLLNDTNMGDQVIIGVIDTGVWPESESFNDNGVGPIPRKWKGGCESGENFRSTDCNRKLIGAKYFINGFLAENKGFNTTESRDYISARDFDGHGTHVASIAGGSFVPNVSYKGLAGGTLRGGAPRARIAMYKACWFHEELKGVTCSDSDIMKAIDEAIHDGVDVLSISLVGQIPLNSETDIRDEFATGLFHAVAKGIVVVCAGGNDGPAAQTVVNIAPWILTVAATTLDRSFPTPITLGNNKVILGQATYTGPELGLTSLVYPENARNNNETFSGVCESLNLNPNYTMAMKVVLCFTASRTNAAISRAASFVKAAGGLGLIISRNPVYTLSPCNDDFPCVAVDYELGTDILSYIRSTRSPVVKIQRSRTLSGQPVGTKVVNFSSRGPNSMSPAILKPDIAAPGVRILAATSPNDTLNVGGFAMLSGTSMATPVISGVIALLKALHPEWSPAAFRSAIVTTAWRTDPFGEQIFAEGSSRKVSDPFDYGGGIVNPEKAAEPGLIYDMGPQDYILYLCSAGYNDSSISQLVGQITVCSNPKPSVLDVNLPSITIPNLKDEVTLTRTVTNVGLVDSVYKVSVEPPLGVRVVVTPETLVFNSKTISVSFTVRVSTTHKINTGYYFGSLTWTDSVHNVVIPLSVRTQILQNYYDEN
What is the function of this protein?
Serine protease that plays a role in the control of the establishment of immune priming and systemic induced resistance.
What are the official names of this protein?
Subtilisin-like protease SBT3.3, Subtilase subfamily 3 member 3, AtSBT3.3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ZN598_MOUSE
Sequence: MAAAAGAEGRRAALEAVAAPERGGGSCVLCCGDLEATALGRCDHPVCYRCSTKMRVLCEQRYCAVCREELRQVVFGKKLPAFALIPIHQLQHEKKYDIYFADGKVFALYRQLLQHECPRCPHLPPFSLFGDLEQHMRKQHELFCCKLCLKHLKIFTYERKWYSRKDLARHRMQGDPDDTSHRGHPLCKFCDERYLDNDELLKHLRRDHYFCHFCDSDGAQDYYSDYAYLREHFREKHFLCEEGRCSTEQFTHAFRTEIDLKAHKTACHSRSRAEARQNRQIDLQFSFAPRHSRRSEGVVSGEDYEEVDRYNRQGRAGRASGRGAQQNRRGSWRYKREEEDREVAAAIRASVAAQQQEETQRVEDREEGSRPKKEEAAARVPEEPRGHRRLPRAQGEGSGSKEASANGPVSQEAFPATGPGPVVALSNTLPPPSPELKEEDFPSLCASTSSCCTAVTPGSVGLALAYPGPPRGKNTFQEEDFPALVSSAPKPSSAPSSLISAWNSGCSKKGNLPTPGSQAVVGGSQPPRKAGKGSRGGRKGGPAPVDEEDSGGLTVQGLRSVPTTVAVSSLLAPATNQSSAKVGKKKKVGSEKPGATSSPLLPPDHTPKPSGAEQVLEAPLSKAEVPVTIVVNGHSEGSALVRSAPKEPPGLPRPLGPLPCPIPQEDFPALGGPCPPRMPPPPGFSTVVLLKGTPPPPPPPPGLVPPISKPPPGFSSLLPSSHSACAPSPTTTTTTTTTTKTPGLAPTPQAYLVPENFRERNLQLIQSIKDFLQSDEACFSKFKSHSGEFRQGMISAAQYYKSCRDLLGESFQKIFSELLALLPDTAKQQELLSAHTDFCSREKPPNSRSKRNKKNVWQTSTQQLGLDCCVCPTCQQVLAHGDVSSHQALHAARDDDFPSLQAIARIIT
What is the function of this protein?
E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation.  Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40S ribosomal protein RPS10/eS10, RPS20/uS10 and RPS3/uS3.  Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide.  Also acts as a component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation.
What are the official names of this protein?
E3 ubiquitin-protein ligase ZNF598, Zinc finger protein 598.
What is the protein family that this protein belongs to?
Belongs to the ZNF598 family.
Protein: GLF_MYCPN
Sequence: MTLFSFPNYVNWNKFDFIVLGAGISGIVLSHVLAQHGKSVLLLEKRNQLGGNCYDKLDETTGLLFHQYGPHIFHTDNQKVMDFIQPFFELNNYQHRVGLQLDNNLDLTLPFDFSQMRKLLDTKTASSLINFFQQHFPAEKHLTLMQLQTINFAPVQQLYQFLKIKVYGPYSVKMWGMPLEQIDPSVLGRVKISLSENSSYFPTATIQGLPKGGYTKAFTKMVDHPLIDLRLNCPANLISVNNNQLLFANQPITKPVVYCGLIDQLFGYCFGRLQYRSLHFEWKRYAVKQHQAYPVMNWPLHPTITRQVEYKQLTQEGLESNQTIVSCETPGAFREGDPRFMEPYYPLNDVSNNALFARYLKLANAIPNIHLLGRLALYQYIDMDRAIAQSLAKAEQLLQ
What is the function of this protein?
Involved in the conversion of UDP-GalP into UDP-GalF through a 2-keto intermediate.
What are the official names of this protein?
UDP-galactopyranose mutase, UGM, UDP-GALP mutase, Uridine 5-diphosphate galactopyranose mutase.
What is the protein family that this protein belongs to?
Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.
Protein: SSUB_BURPS
Sequence: MTGTTLAATYGPISGADLEAELAQPRIADGDAQDAAVYERDGGAHAPPDGDRADVRRAAGAGDASVRLTRVSKRYGERAVLADVDLSIGRGSFVSIVGRSGCGKSTLLRLVAELETPSAGTLVKRGDGGGALDTRIMYQEARLLPWKTVLQNVMLGLGRRAKDDARAVLDEVGLLARANDWPAQLSGGQRQRVALARALVHRPQLLLLDEPLGALDALTRIEMHALIERLWREHRFTALLVTHDVQEAVALADRVLLIEAGRIAFDQRVPLDRPRARASAAFAALEDRVLQRVLTGSDAAPAAPNAAGPEGASRGRAAPASGLRWAV
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LPLA_AERHH
Sequence: MSRLRLLLSDSHDPLFNLAVEECIFRQMDPNQRVLFLWRNANTVVIGRAQNPWKECNTRRMEEDGVTLARRSSGGGAVFHDLGNSCFTFMAGKPEYDKSVSTAIVLDALTRLGVEAFASGRNDLLVATPDGERKVSGSAYRETHDRGFHHGTLLLDADLGRLANYLNPDPKKLAAKGISSVRSRVANLCELLPGIDHPQVSEALQEAFFSHYGERVQPEHISPEQMPDLPGFAETFARQRSWEWNFGHAPAFSHQLDERFGWGGVELHFDVEKGVIGRAQIFSDSLDPAPLDALAARLPGTAYRADALYDLLRQWRSEFAAREAELEELSRWLLAALR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STR17_ARATH
Sequence: MDSLHVLRSFLLLFIVFNHLPRTTTSMSEPKVITIDVNQAQKLLDSGYTFLDVRTVEEFKKGHVDSENVFNVPYWLYTPQGQEINPNFLKHVSSLCNQTDHLILGCKSGVRSLHATKFLVSSGFKTVRNMDGGYIAWVNKRFPVKVEHKELKYDEL
What are the official names of this protein?
Rhodanese-like domain-containing protein 17, Sulfurtransferase 17, AtStr17.
Protein: ADDA_CLONN
Sequence: MGEVKWTKEQQQAIDVHGCNLLVSAAAGSGKTAVLVERIIKMITDIKNPVDIDRLLVVTFTNAAASEMKERIGKAIGKELTKHPKSKQLQRQLTLLNRASITTIHSFCLETIRNNFHYIDLDPNFRIGDETETVLLKGEIIEGIFEDLYEPENCTQEFLNLVEFYSSNKDDVALQNIVLNLYDFVMSSKNPKKQLQDMAEQFNVDESYNFGESKWAKVLMDDVELELSGLKDMMEEALKLINDTNGLDAYLEGFTDELLMINDLILNAKTSWDSLYNGLSEVKFGRLKTCRNCEDKKTQEKVKDIRNKVKKQLQDEIKKKITSYSTKEIVTDLRNLYPIMKSLCDLVIEFMDRYSKAKKERGIIDFNDFEHFCLEILGHEEVALKLRQKYIEILVDEYQDSNYVQEAIINSIARRHEETGNPINVFMVGDVKQSIYRFRQAKPELFLKKYNSYLEGENAKERKVNLFKNFRSRKEVLDGVNFIFKQIMSENIGELEYGDDEALYLGADFEQYEDKSLVGGPIELNLIEKSKDETKEEESEEEEILSNIQVEARFVAKKINELVNPKIGEPFKVYDNELKAYRNVEYRDIVVLLRSTSNWAPVFTDEMKENLIPAYADVGNGYFETVEIKTILSLLEIIDNPRQDIPLIAVLRSPIASFTPEELIDIRLENKDGDFYGGLLKVASSEDRDDNWILFKRKCNSFLEKLNYWREKSIHMPIDEFIWYLYMETGYYGYVGALAGGMQRQANLKILFQRARQYEKTSYKGLFNFINFINRLKVSSGDMGSAKILGENDNVVRIMSIHKSKGLEFPVIILSALGKNFNMQDLNKRILYHDELGFGPDYIDLDKRIIYETVPKSALKKKIKLESLSEEMRILYVALTRAKEKLILTGAVNDIEKSAKKWSYALEGEDYKLSQYQVMTGKNYLDWICPVIMRHKDGEVLRELAGIEIFEKVNLLSDESSWKITTDNISGILQNDDETNEIILEDIKEIEDIEESSSYYDEINERLNFKYKYIESSKLPTLLTVTELKRMKNSSMYEDYSRDMYTPKLVKKPMFMEKDKKLKGAEKGTAMHAVMQKINYSEELTIEDINRQMETMVEKEFITKEQADSVEAEKILNFFKSNIGKRLLKAENVRRETPFHMELKSTEIYESLPKEIYENENIMIQGIIDCYFEEEDGIVLLDYKSDYFKEGQEEAIIKKYKVQIDYYARAIEELTGKVVKEKYLYLFYGDKEVEIK
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: RECA_RHOBA
Sequence: MVKKPRMATPAASKGVKLDPGMKTILEKEPGLKTTLQQIEKSFGDGAIMPLGASQKLTIDCISTGSLSLDMALGGKGIPRGRIIEVFGPESSGKTTLALHIGAEAQKSGGIAAIIDAEHAFDPSWAKKLGVELDSLLVSQPSSGEEAMQICEMLVKSNAVDVIIIDSVAALVPKAELEGEIGDSHVGLQARLMSQSMRKLTGAIAKSKSAVVFINQIREKVGVMFGSPETTPGGRALKFYCSCRIDVRRIGSLKDGEEQVGQRVKAKIVKNKVAPPFRIAEFDMMHSNGISFEGDLLDLGTENKVVNRSGSWFKYGDTYLGQGKEKARNFLIENPDVSDEIKQKVLAAGGFVAPLEVDADESEEAVEDGEAVANS
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S22AG_BOVIN
Sequence: MGSSNLELIFDSVGHFGRYQIFLYFICAFQNISCGIHYLASVFLSVSPQHTCRPPGNVSQVLFQDLSTWQLEDIWTQFSVGREDRILVQLQDGAIWELTSCQRFRRDDQSSLDYEYSGQKSSFPCLDGYIYDRSKWLSTVVTQWDLVCNREWFGRLIQPTFMFGVLLGAVIFGYLSDRAGRRLVLWASSTGVFLFGIAAAFTFDYYSFIVARFLLAISGSGYLVVVFVYVTEFVGMKSRTWASIHLHSFFAFGTMVVALTGYFVRTWWIYQIVLSSVTVPFVLCCWMLPETPFWLISGGKYEEAQKVIDTMAKWNRTRPCKLSEILSLDHDGSAGNKPSQVEKHTLSELFYDWSIGTRTLILWLIWFTGCLGFYTFSLNSVHLGGSEYLNLFLMGVVEIPAYVLVCLGMDRVGRRNILIFSLLSSAVTSGVIMVIPKDYHVWLVVASMAGKFFIGAAFGLIYLYTAELYPTIVRSLAVGSGSTVGRVGSIVAPLCIYLSSVWIFMPQLLVGTLALVSGVLTFLLPETLRRPLTTTWEETEKESSSGKLLSTTSNTVLENVTVENSEDSSLNK
What is the function of this protein?
High affinity carnitine transporter; the uptake is partially sodium-ion dependent.  Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa.  Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin.  The uptake of TEA is inhibited by various organic cations.  The uptake of doxorubicin is sodium-independent (By similarity).
What are the official names of this protein?
Solute carrier family 22 member 16, Carnitine transporter 2, CT2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane.
Protein: BRXA_BACCH
Sequence: MVKEQVYKSTIKSRPLLFLEMKKVSILLNKGFKEFEVKEKAISENIFQVNTESRKKEIASSVLARLKILDDYLIREIGHGDIESSKAIVLYSIMKTDRLFFEFMNEVFKEKFVFGETFLTDADFNIFFENKQQQSEKVASWNDYTFYKLKQVYIRILFEAGYLKNQKGNREIERPLLNIDVVEHIRALGDGIYMDILVGE
What is the function of this protein?
BREX systems (bacteriophage exclusion) provide immunity against bacteriophage.  Part of a type 1 BREX system.  This system allows phage adsorption but prevents phage DNA replication, without degradation of the phage DNA.  Methylation of bacterial DNA by PglX probably guides self/non-self discrimination.  When the brxA-brxB-brxC-pglX and pglZ-brxL operons are transformed into a susceptible B. subtilis strain (BEST7003) they confer resistance to bacteriophages SPbeta, SP16, Zeta, phi3T and SP02 and partial protection to phages SP01 and SP82G (these include lytic and temperate phage).  They do not protect against phages phi105, rho10 or rho14.  Additionally confers a very slight reduction in efficiency of plasmid transformation.
What are the official names of this protein?
BREX protein BrxA, NusB-like RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BrxA family.
Protein: BACE2_BACIU
Sequence: MKQLKPNSKYLLFGQALSFMGDYCVLPALLILSTYYHDYWVTSGVIAVRSIPMVFQPFLGVLVDRLDRVKIMLWTDVIRGVIFLGLTFLPKGEYPLLFLALLFVSYGSGVFFNPARLAVMSSLEADIKNINTLFAKATTISIIVGAAAGGLFLLGGSVELAVAFNGVTYLVSAFFISRIKLQYVPIQSENVREAFQSFKEGLKEIKTNAFVLNAMFTMITMALLWGVVYSYFPIVSRFLGDGEIGNFILTFCIGFGGFIGAALVSKWGFNNNKGLMYFTVLSIVSLALFLFTPIFAVSVIAAILFFIAMEYGEVLAKVKVQENAANQIQGRIFSVAEASIGLCIAVGSMLINIVDAAVIMAFIVLLVSGLFLHTKLVNKSFSERNNESEQIHL
What is the function of this protein?
Part of the bacilysin biosynthesis operon.  May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic (By similarity).
What are the official names of this protein?
Putative bacilysin exporter BacE.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: XERDL_STRPF
Sequence: MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLLYQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINTDIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLSQILIPFLEQQLIGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFILKEKLAGKSIIELSDILGLKSPVTLEKYYKS
What is the function of this protein?
Putative tyrosine recombinase.  Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
What are the official names of this protein?
Tyrosine recombinase XerD-like.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_BURPS
Sequence: MITLTPGRLTLPQLRRIARENVQIALDPASFAAIDRGAQAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQKNLVLSHAVGVGEPMARPVVRLLMALKLSSLGRGHSGIRRVVMDALVTLFNADVLPLIPVKGSVGASGDLAPLAHMSAVLLGIGDVFIRGERASAAEGLRVAGLAPLTLEAKEGLALLNGTQASTALALDNLFAIEDLYRTALVSGALSVDAAAGSVKPFDARIHELRGHRGQIDAAAAYRSLLDGSAINVSHRDCDKVQDPYSLRCQPQVMGACLDQIRHAAGVLLIEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLAIAAAEIGALAERRIALLIDATLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATFAARKLADIAENVANILAIELLAAAQGVDLRAPHATSPALQHAMKTIRADVAHYDLDHYFAPDIAVVARRVRERAFATLSPLSFESEQ
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPC9_YEAST
Sequence: MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITRNVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEKLQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.  The RPC25/RPC8-RPC17/RPC9 subcomplex may bind Pol III transcripts emerging from the adjacent exit pore during elongation.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC9, RNA polymerase III subunit C9, RNA polymerase III subunit C17.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXA_HELPJ
Sequence: MAKKKIAISCGDIQGVGLELILKSHKEVSALCEPLYLVHSELLERANQLLDNAYETKTLNAIAIDAPLPLLNSSTIGKVSTQSGAYSFESFKKACELADSKEVDGICTLPINKLAWQQAQIPFVGHTDFLKQRYKDHQIIMMLGCSKLFVGLFSDHVPLSAVSQLIQVKALVKFLLAFQKSTQAKIVQVCGFNPHAGEEGLFGEEDEKILKAIQESNQTLGFECFLGPLPADSAFAPNKRKITPFYVSMSHDVGLAPLKALYFDESINVSLNAPILRASTDHGTAFDIAYQNKANHKSYLNAIKYLA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.