PharMolix/UniProtQA huggingface dataset:
Protein: SNX15_RAT
Sequence: MSRRAKKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDIKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVPIPALNNSPQLKEFFRGGEVTRPSEVSRDLQILPPPLIPTPPSDEARLLQPLPAERRGQEELEVPVDPLPSSPAQEALDLLFCCDSTEEASSSPARGPLSEAELALFDPYSKEESTGPSPTHTSELAAMEVQSKRLDQEPWEPGGREEEEAEDGDPAPAYLGQATELITQALRNEKAGAYAAALQGYQEGVHILLQGVSGDPSPTRREGVKKKAAEYLKRAETLHAHLP
What is the function of this protein?
May be involved in several stages of intracellular trafficking.  Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN (By similarity).
What are the official names of this protein?
Sorting nexin-15.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: JMJCC_DICDI
Sequence: MNIDRIDKPTREQYEEYILKNQPFIITGVVNNWISFNKKWIPSQNIEDDYFLSILENKGIPVREIGIDVGEWLGKTKNINFSIFWKKWREHYFNFKNEKNNQSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKPKYYLASLPIQTYFKELINDFEIPEIPKEQNKNGNLWIGFKDQITPLHHDWSSGDPGMDGLHAIIIGRKQFKLFDPIVNVNCFKRKKEWGKFHQSEFDLDNPDFNKFPEAKNFKIIEIQLNQGEMLFIPKLWWHHVKTLEPSISINFWFQHIGSELLKSNKLWCHMEQYLNAVFEMDATKISNDKFKKIIKYLTNDNNGGDGDGDGDGDQIIQKYKDDNLKLIQLPKFIDSFSNAVNNPIFKNHPKKDQFKFEITEKVNQWIEEKKKEINENKIVIL
What are the official names of this protein?
JmjC domain-containing protein C, Jumonji domain-containing protein C.
Protein: HACL2_ORYSJ
Sequence: MKQGQGAHLSGQRIGHHPTAQMNPGDGDGNGRHQVASGHASADPELMNLRIRMTNRLIWELLSREPKLQTRPRKLVSDLAKRFEAVIYKKNPNKAAYYSILNGEIFPHLQHALSTHMAQHQQGQQMLQQLTSSSSYGTTIPIPDVVQNASGNTRALYEMDNTSGPMSNGHHHFSANFPLHSTTKGASLEMSAVSMQEGKITHMIPTPGSSNQQSLPGNFHYSTGTGYLNGKSNVMAQMQEQQAPFASKINCCPVQRDLGGYAGSGVHSDILNNSSPYGVSEAHMIDGMGLHRSNVQVINRTVVPETFINPSPYGISPNKPLQRHVNPSTRSTPTPADIAASTSFNGTGSSALSTTSYLDMTTVNSLPKSRMDSGLIMSQPTIQSFQTEYYIQTEGLDLQEKISLEQLHQQVNQLHLIQPHSQYAQNQCSLKLQQQNSLHHLVMSRGNVLTQCHLGSDHAEKLLDKRNQLHSELVSSQINEHVGLTNLQGHYEQTQYHDNYKKGQMSASSQNLGIPAPHDLLPPQQQFDDGSYRLSCFLKETYTKPLQPHCKSKPMKEVIMTSLLSGKIQDGFCQKKMARDREHHPIISGWHSAGCAATSFGSEEVMENTKQYHAQARWLLFLFHAKSCTSPPGSCKSSYCDRVRELVVHLTDCQIKDCSYRHCRESKMVSDHYKNCINEHCHVCCKAKEMLRRSSELAHKQNPAEPILITQHNMNQRSADRVHGDRMDIDQAVETFDDQPPAAKRPKLQLVSPDASENVPVCQKNPGFMLQEAHPRQLDQNKKMVPDQEVDVGLDIRHPQVTLVSCHGSDEKIGAAQNTVIPGALNKIHCHVQQETVVADKESVTVVDVKKKTGSVDVTISKTGKPKVKGVSLMELFTPEQIHEHINSLRQWIGQWVQCDKCECWQHQICALFNARRNDVEEAEYTCFKCYIEEFKRGLRMPLPESVVRGAKDLPRTLLSDHIEERLFKRLREERQERANKLKTSLDEVPGADGLVVRVVSSVDKKLEVKPHFFKILQEDNYPAEFPYKSKAILLFQKIEGVEVCLFGMYVQEYGAECKFPNQRRVYLSYLDSVKYFRPDIETVSGQALRTYVYHEILIGYLEYYKQRGFTSCYIWACPPVKGEDYILYCHPEIQKTPKSDKLRQWYLSMLQKAIKENIVVELTNLYDQFFVTAKECKIKVSAARLPYFDGDYWPGAAEDIINQLQLEGDGKLLKKGRVNKIITKRALKAAGHTDLSGNASKEAMLMQKLGEIICPIKDDLIMVHLQYSCSHCCTFMVSGRRWVCNECKSFYICDRCYNAEQRLEEKERHPSNSKCLHILHPVEIVGVSEDTKDRDIILENEIFDTRQAFLSFCQGYHYQYDTLRRAKHSTMMMLYHLHNPTGPAFVATCNVCNCDIENGQGWDFKSFERKQNQLSESRRMASVNERVRQRVAEVTRHE
What is the function of this protein?
Acetyltransferase enzyme.  Acetylates histones, giving a specific tag for transcriptional activation.
What are the official names of this protein?
Probable histone acetyltransferase HAC-like 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: INHB_DROME
Sequence: MRFAFDSNHSQSGAPFKGSRCFFNCQCICCRQGCCVVVVKCCCCFNLNCCNSLGSRKSFPQPAAMRKKVADLEVLRVSRFVAVILVLARWVTAVATLLTSCILLDIFSVPGQSGVADRSQASSRTVHVSVPTTPNETPSSTSETKLKLLYGYTSYDINNDQQVKSNNLCRVLCKSRNRKRQRRRRRRRNHRRRRHRYTKRLHHLMQDNMSGFEQRLNFSDAKCQSLETNYGTNYDLVQGGKLFSQSERSLLVSPLREIEAPWPAIHGSMRNCSKIKRNRANLIWLLIGLVWFEVKLINCNGISSSNYYASNLESHKGCTLCHESGKPNIYTDKDNPHTDYNIYNKYHSNNNFNKKTNQPHNNIAPSDEVRLESIKRQILTKLGLSHKPNVSHPLPKQFIWETIYRVDGGRMIPNNAFGSSGKNLDQKTIKLRAFASPGSHLFNGRGGRTDQRSERDPSHHKYRSPFDFTFNISKNNVYGKVLRNRSLERIDKKNSFLNGWTENRQLKINSQIASMPIELKSHHNSSPKELKSGAVRKVNGINGTQMNENALKKSTYPIDINHSIDNKTHTGKNGEMSHNDYEYFNDYSVQTHDKNRYHEGRSSIGYQPAIHNIEYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRSAQIHIRIDKPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAIIFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLLIDCTGCGGRYSLHLFQTSKLRGNSSDYLSTNPNRPFLVLHTESSRTRRVRRRAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFANYCRGDCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGMRPCCAPIKFSSMSLIYYGDDGIIKRDLPKMVVDECGCP
What is the function of this protein?
Controls several aspects of neuronal morphogenesis; essential for optic lobe development, EcR-B1 expression in larval brains, mushroom body remodeling, dorsal neuron morphogenesis and motoneuron axon guidance.  Ligands Actbeta and daw act redundantly through the Activin receptor Babo and its transcriptional mediator Smad2 (Smox), to regulate neuroblast numbers and proliferation rates in the developing larval brain.
What are the official names of this protein?
Inhibin beta chain, Activin beta chain, dAct, dActivin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: S39A9_MACFA
Sequence: MNMSTATTTHSCVPILVFPSYWASFSCCWWTRLVTPMCILLTPTQCEDDEDENLYDDPLLLNNPEAARSSNSKTTTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFSLAAPVMSMVTYLGLSKSSKEALSEVNATGMAMLFSAGTFLYVATVHVLPEVGGIGHSHKPDATGGRGLSRLEVAALVLGCLIPLILSVGHQH
What is the function of this protein?
Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis.  Participates in the zinc ions efflux out of the secretory compartments.  Regulates intracellular zinc level, resulting in the enhancement of AKT1 and MAPK3/MAPK1 (Erk1/2) phosphorylation in response to the BCR activation (By similarity).  Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1 (By similarity).  This pathway contributes to CLDN1 and CLDN5 expression and tight junction formation between adjacent Sertoli cells (By similarity).  Mediates androgen-induced vascular endothelial cell proliferation through activation of an inhibitory G protein leading to the AKT1 and MAPK3/MAPK1 (Erk1/2) activation which in turn modulate inhibition (phosphorylation) of GSK3B and CCND1 transcription.  Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process (By similarity).
What are the official names of this protein?
Zinc transporter ZIP9, Solute carrier family 39 member 9, Zrt- and Irt-like protein 9, ZIP-9.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BDNF_PANTR
Sequence: MTILFLTMVISYFGCMKAAPMKEANIRGQGGLAYPGVRTHGTLESVNGPKAGSRGLTSLADTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR
What is the function of this protein?
Important signaling molecule that activates signaling cascades downstream of NTRK2.  Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2.  Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD).  Binding to NGFR and SORCS2 promotes neuronal apoptosis.  Promotes neuronal growth cone collapse.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. SUBCELLULAR LOCATION: [BDNF precursor form]: Secreted. Note=A proportion of BDNF is secreted as immature precursor (proBDNF).
Protein: FLOA_PARD8
Sequence: MEITFLPLILLGAAVLLLAIFFYYVPFLLWISAKVSGVNISLIQLFLMRIRKVPPYIITRAMIEAHKAGIKTLTRDELEAHYLAGGHVEKVVHALVSASKANIDLPFQMATAIDLAGRDVFEAVQMSVNPKVIDTPPVTAVAKDGIQLIAKARVTVRANIKQLVGGAGEETILARVGEGIVSSIGSSESHKTVLENPDSISKLVLRKGLDAGTAFEILSIDIADIDIGKNIGAFLQMDQAQADKNIAQAKAEERRAMAVALEQEMKAKAQEARAKVIEAEAEVPKAMADAFRTGNLGVMDYYKMKNIEADTSMREAIAKPTGAPSKPLKD
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: LEUC_RHOP5
Sequence: MSATKPTTLYDKIWNDHLAHEAEDGTCLLYIDRHLVHEVTSPQAFEGLRTAGRKVHAPEKTLAVVDHNVPTTDRSKPNPDPESAEQIAALAENAREFGVTYYNEFDKRQGVVHVIGPEQGFTLPGTTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAKNMRVTVDGDLPAGVTAKDIILAIIGEIGTAGGTGYVLEYAGSAIRALSMEGRMTVCNMSIEGGARAGLIAPDEKAYAYLKGRPLAPKGEAWDAAMRYWQTLRSDEGAHFDHEIRLDAAALPPIVTWGTSPEDVISITGKVPNPADIADEAKRLSKERALAYMGLNPGTKITDIKIDRMFIGSCTNGRIEDLRAAAKVAEGKTVNANVNAIIVPGSGLVKEQAEAEGLDKIFIAAGFEWREPGCSMCLAMNPDKLAPDERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGHFVDIREWR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CIP2A_CHICK
Sequence: MDASGCMKSLLLAATQYRAAKTPSNAALVQRSLEVISGLKLTRLFASNQILPSECLNCLVELLEDANIDPPLTLSLVTLLSQLASDSETREALRDTYSLTNVLAGVVHRSSTNLSDPVLLQSIQLLQRLTYNVPVFCAGANIDELISFLMHHVQSTEDELTIPCLGLLANLCRHNLPIQTQIKSLNNVKSFYRTLISFLAHSSLTMVVFALSVLSSLTLNEEVGEKLFHARNIHQTFQLIFNIVVNGDGTLTRKYSVDLLMDLLKNPKVADYLTRYEHFTSCLGQVLDLLHGKDPDSSSKILELLLAFCSVVELRHTLRQAILEPSGLPVSGNTRFVTRSKTFEPSVALVHLSNQPLEGSEDCSVLALQLFKEVFEDVISSGNSASAEHFVDLLLPVLLDHLQTPEQIVDELLVKKKCERMVKTINVLTVLCRDDILKTHASKLLTASQCVSLIEHQFSYSGIDAGFGTKVVDSKMCKLAADIILKTLDLMSRLKQDVPGMEVSFYKILQDQRLITPLTFALTSDYREQVQVGLRILFEAAPLPDFPAILLGESIAANNAYRQQEKEHASKRIQLQSPLISNVTVSSSSCANGDESTASNVQELIQKLHSGLEVKEPITDMRISDIMDIYEQKLSSLASKETRLQDLLEAKALALAQADRLMAQYRCQRAQAESEARTLAAMLKDAERKNEELNVLLKAQQVESERAQTDIEQLFQHNRKLQTVAEEHEMLKKSSVDLLQRYETTERQHKDLRITCNSLNKEIEAMKKLNESLKQQNDRTAAQLVESEEHRKELQQQLHDRESKIASLQQKIKGLEEKLKAQQKEKNSMEETVDVLRKELSKTEQARKELSIKASSLEVQKSQLEVRLEEKEALVKLQKEELNKHSTMIAMIHSLSGGKLSAEAVNLSL
What are the official names of this protein?
Protein CIP2A homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Cytoplasm.
Protein: HCP_ALIFM
Sequence: MFCIQCEQTIQTPTTKGCSFAQGMCGKTAEVSDLQDILVYALQGVSFWAEQGRKVNVIFDEIDQWAPKAFFATLTNVNFDPERVIEFALQAQAYKQQLEETVRAAATVTNTELDELSPAAKFELPTEAEQIIALAPQAAVNRGHETQHEDIIGLRLLCLYGLKGAAAYMEHARVLGQTDKDVFAEYHQIMAWLGTDPTDLGELLDCSMKIGLMNYRIMEMLDTGETDTFGHPEPSQVNVKTIEGKCILVSGHDLHDLEKILQQTEGKGINVYTNGEMLPAHSYPELKKYPHLVGNYGSAWQNQQKEFANFPGAIVMTSNCLLNPNVGQYADRLFTRSIVGWPGVAHIEGDDFTTVIDCALAQEGFKHNEIEQMITVGFGRNALMAAAPAVVEQVKEGNISHFFLVGGCDGDKSERSYYTDFTAQAPEDSVILTLACGKYRFNKNQFGDINGIPRLLDVGQCNDAYSAIQLALALAKEFDCDINELPLTLVLSWFEQKAIVILLTLFALGVKGIYTGPTAPAFLTDNLLAIIQEKFDMRSIGNVEDDLKAILAA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_AGGAC
Sequence: MAIVKCKPTSAGRRHVVKVVNPELHKGKPFAALLDTKSKTGGRNNYGRITTRHIGGGHKQHYRLIDFKRNKLDIPGVVERLEYDPNRSANIALVLYKDGERRYILAPKGLAAGDQIQAGAHAPIKVGNALPMRNIPVGSTVHNVELKPGKGGQIARSAGSYVQIIAREGNYVTLRLRSGEMRKVLAECSATIGEVGNSEHMLRVLGKAGANRWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRHNKRTDKYIVRRRGK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RUVA_RHIE6
Sequence: MIGKLKGTIDEIGEDYVLVDVHGVCYVAHCSARTLSKLGSAGEACVLFIETYVREDQLKLFGFMTALEREWFNLLQSVQGVGAKVALAVLSTLTPSELANAIALQDRAAVSRAPGVGPKVAMRLVTELKNRAPAFAGEAINIALKQELGEGVAAAPVADAVSALTNLGYSRDQAANAVAAAMKTAGDGADSAKLIRLGLKELAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MSX2_MOUSE
Sequence: MASPTKGGDLFSSDEEGPAVLAGPGPGPGGAEGSAEERRVKVSSLPFSVEALMSDKKPPKESPAVPPDCASAGAVLRPLLLPGHGVRDAHSPGPLVKPFETASVKSENSEDGAPWIQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSGFSLPFPINSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS
What is the function of this protein?
Acts as a transcriptional regulator in bone development.  Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation.  Probable morphogenetic role.  May play a role in limb-pattern formation.  In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE).  Binds to the homeodomain-response element of the ALPL promoter.
What are the official names of this protein?
Homeobox protein MSX-2, Homeobox protein Hox-8-1.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IRL1A_DANRE
Sequence: MTALNPVLFLLCGVSVSLSLKVVSKRGSVDGCTDWSVDYLKYRVLHGEPVRIKCALFYGYIRANYTQAQSIGLSLMWYRSSGLGHGDFEEPISFDGTRMSKEEDAIWFRPAELQDAGLYSCVLRNSTFCMKVSMTLLVADNDTAGCYNSKLRYTEKGELGKSKDISCPDIQDYVQPGEKPQITWYKECNVQQWRSSVLQTADLLAIQDVREDDIGNYTCELLFGGFLVRRTTYLSVTAPLTEEPPRILFPSENKLLAMDVQLGSMLNLTCRAFFGYSGDISPLVYWMKGEKFIEDMDQSRIRESEIKTVREHLGEQEVSITLTIDSLEEVDLGNYSCYAENGNGRRQANVQIGKRVELMYTVELAGGLGAILLLLALLLSVYKCYRIELLLCYRHHFGGEDTDGDNKEYDAYLSYSKVELDQWGQELQEEERFALEILPDVLEKHYGYKLFIPDRDLIPTSTYIEDVSRCVDMSKRLIIVLTPSYVLRRGWSIFELESRLRNSLVSGDIKVILIECADLRGVINYQEVEELKQSIKCLSVVHWNGPQSNKPGSRFWKQLRYTMPYRRPQQTITNHALDTSEPGPFADLQTVSAISMATATSAALAPAHPELRPSLRSSYRSHSLARQKHSHYRSYDYELPFTAGGTLPPQHTYCNLPLTLLNGQRPVNNKTLRQHSLDEHHGNNAMLPLLPRETSISSVIW
What is the function of this protein?
May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel.  During presynaptic differentiation may regulate both synaptic vesicle accumulation in axon terminals and subsequent axon terminal remodeling.
What are the official names of this protein?
Interleukin-1 receptor accessory protein-like 1-A.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=May localize to the cell body and growth cones of dendrite-like processes.
Protein: RS19_STRP7
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NQOR_XANP2
Sequence: MAKVLVLYYSAYGHIEQMAEAAAAGAREAGATVDIKRVPDLVPEEVAKSAHFKLDQKAPIATVAELAEYDAIIVGVGTRFGRMASQMANFLDQAGGLWARGALNGKVGGAFTSTATQHGGQEVTLFSIITNLMHFGMVIVGLDYGYGAQMTLDEVTGGSPYGATTITGGDGSRQPSAIELDGARYQGRKIAETAIKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: PF23B_DANRE
Sequence: MLEIMSEHQDSLLKCKAETLPSERRKRTVEDFNKFCSFVLAYANYIPSQKEEGPWSPASSSSPNGSGASGEGSVLGGASSNMSPSWNHGTSDLHTIHTFVHKARANKSSKSMRRLSPDGALEDNMCLKDSFYESQAASKAERKKDKKLKRLSLGSGAGDSSSSGGEKRARIKHSKNSKQSKAYKKLKSSAHSESDSENGLGHREERSEHRLQVQVKEEKNEEDEEEAIREADMSSSEGETWIADEDIMVESGDDSWDLITCYCGKPFAGRPMIECSQCNVWVHLSCAKIKKSNVPDIFNCHKCRDSRRSSHKKDS
What is the function of this protein?
Acts as a negative regulator of autophagy.
What are the official names of this protein?
PHD finger protein 23B.
What is the protein family that this protein belongs to?
Belongs to the PHF23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RS13_HAEIG
Sequence: MARIAGINIPDHKHAVIALTAIYGIGKTRSQAICAAAGIAEDVKIRELSEEQIDKLRDEVGKFTVEGDLRREVTLNIKRLLDLGCYRGLRHRRSLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL27_AROAE
Sequence: MAHKKAGGSSRNGRDSESKRLGVKRYGGQFVLAGNIIVRQRGTEYHPGENVGIGKDHTLFALKDGTVQFTIKGAQRRRTVVIVPEAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SECF_METKA
Sequence: MGLFEKYVSNLNRLLILTMVFAVICAGSTLALGVKKGIDLKGGTMVILKTEKDPDTVTSEASRILGVSDVEAIRSSQGDVIVQVPKYLSADDVNKLARAVGGEVESVQTIGPALGRVFWESVKVAVPLALVAVSIVVFAIFRKPLLSAAVLGALALDLVDALGLMALTGVPLTLASFAGLLMIIGYAVDSNILLSMYTVKRRRVRRVDRAIADSFKTGITMVATTTAAACALFLLSMSEAMFEIAAVVIFGLIADVLNTWIFNAWVIREKIAGR
What is the function of this protein?
Involved in protein export.
What are the official names of this protein?
Protein-export membrane protein SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPEH_ACIF5
Sequence: MRSLGHQIVADFYHCDGSTLSDVDFVTDAMLEAARRANCTIVTQTFHHFSPYGVSGAVIVAESHLAIHTWPEYGYAAVDVFTCGDIIQPEDALNYLKEAFGAGQVSTMEMKRGQVDMMGVPAHELRVKPALCA
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: YN003_YEAST
Sequence: MENSSSSSKALLPASGSPSPWFICRMLSKVTL
What are the official names of this protein?
Putative uncharacterized protein YNR003W-A.
Protein: ADE_YEAST
Sequence: MVSVEFLQELPKCEHHLHLEGTLEPDLLFPLAKRNDIILPEGFPKSVEELNEKYKKFRDLQDFLDYYYIGTNVLISEQDFFDLAWAYFKKVHKQGLVHAEVFYDPQSHTSRGISIETVTKGFQRACDKAFSEFGITSKLIMCLLRHIEPEECLKTIEEATPFIKDGTISALGLDSAEKPFPPHLFVECYGKAASLNKDLKLTAHAGEEGPAQFVSDALDLLQVTRIDHGINSQYDEELLDRLSRDQTMLTICPLSNVKLQVVQSVSELPLQKFLDRDVPFSLNSDDPAYFGGYILDVYTQVSKDFPHWDHETWGRIAKNAIKGSWCDDKRKNGLLSRVDEVVTKYSH
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.  Also exhibits a low activity towards N(6)-substituted adenines that are commonly known as the plant hormones cytokinins.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FHL5_MACFA
Sequence: MTTAQFYCQYCTASLLGKKYVLKDDSLFCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHGGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNFCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCVDCYNHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDSDI
What is the function of this protein?
May be involved in the regulation of spermatogenesis.  Stimulates CREM transcriptional activity in a phosphorylation-independent manner (By similarity).
What are the official names of this protein?
Four and a half LIM domains protein 5, FHL-5.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclei of round and elongated spermatids.
Protein: LSRD_PHOTE
Sequence: MNIGQRYGWEFALAVLLVMEILLFGIANPRMLDINILLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAISLGVMNQADIPMAAAIPLTLNVGAMCGIINAALILYTGVNPLVITLGTLYLFGGSALLLSGIFGATGYEGIGGFPQAFTDFANLTLLGLPVPLAMFIICVLVFWLFMHRTHSGRNIFLIGQNNKAAYYTAIPVARTLYFIYSLTGIAAAIAAIVLVSYFGSARSDLGSSFLMPAITAVVLGGANIYGGSGSIIGTALAMLLIGYLQQGLQMIGIPNQISSALSGALLIIAVVGRSISLHRHQIRGWMQRRRNQKLPS
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrD, AI-2 import system permease protein LsrD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLS3_PHYTS
Sequence: FFSMIPKIATGIASLVKNL
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Phylloseptin-3, PStar 03.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYS_HALWD
Sequence: MIDRQLLRKNPDAIRGALDEKGVTDVNLDQILTLDQEWRERKARGDELRHERNQISSKIGKLKAAGDEDAASEAIAQSQELKNELEEIEREADKLKSELDTAMLKIPQVPDDAVPVGTDESENVERRREGFDSLRSLPDTVIPHYDLGEELEILDFERGAKVTGGGFYFAKGDGARLEHALVQFMLDIHREQGYQDVFPPIPVNSQSMVGTGQFPKFTEDAYRIGETNDEPWDNDDLWLCPTAEVPVTNMYRDEILLDDDLPVKIQAYTPNFRREAGEHGTETRGIVRVHQFNKVELVNFVRPEDSAERFDGLLTEAEVVLQRLGLPYRILEMCTGDLGFTQRKKYDIEVWAPGDDMATGPDIGGRWLEVSSVSNFGAFQSRRAGLRYRPERHESASYLHTLNGSGVAVPRVMVAIMEYYQNDDGTITIPEPLQPYMNGLSVIEGHDPVGEAAVGAGKRE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.