PharMolix/UniProtQA huggingface dataset:
Protein: LRR70_HUMAN
Sequence: MCGLQFSLPCLRLFLVVTCYLLLLLHKEILGCSSVCQLCTGRQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECNCKLLGLRDWLASSAITLNIYCQNPPSMRGRALRYINITNCVTSSINVSRAWAVVKSPHIHHKTTALMMAWHKVTTNGSPLENTETENITFWERIPTSPAGRFFQENAFGNPLETTAVLPVQIQLTTSVTLNLEKNSALPNDAASMSGKTSLICTQEVEKLNEAFDILLAFFILACVLIIFLIYKVVQFKQKLKASENSRENRLEYYSFYQSARYNVTASICNTSPNSLESPGLEQIRLHKQIVPENEAQVILFEHSAL
What is the function of this protein?
Renders cells highly sensitive to the activation by cytokines and lipopolysaccharide (LPS).
What are the official names of this protein?
Leucine-rich repeat-containing protein 70, Synleurin.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CHEB_ALIF1
Sequence: MAIKVLVVDDSSFFRRRVSEIINSDPRLEVIDVAVNGKEAVEKAKSLKPDVITMDIEMPVMDGISAVREIMKACPTPTLMFSSLTHDGAKATLDALDAGALDFLPKKFEDIARNRDEAVSLLQKRIAEIARKKSFMRRPVLSSQSTSTVESRTATTRTATSALTASPVKAAPAAPIAQRFKATGKKYQLTAIGTSTGGPVALQKILTAIPANYPHPIILVQHMPATFTAAFAARLNNLCKIQVKEAEDGDVLKPGCAYLAPGGLQMMVDGRPGASRLKILDGGERMNYKPCVDVTFGSAAKVYGDKVLSMILTGMGADGREGCRMLKAGGATIWSQDEQSCVVYGMPQAVDKAGLSSESLPLDRIAERMLVEVGLK
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_BURP6
Sequence: MSIIDNRKAFFDYHIEERYEAGLVLEGWEVKALRAGRGQIKEGYVVVKHAEIFLIGTHISPLPEASTHIKPDPVRTRKLLLHRDEIKKLIGKVEQRGYTLVPLNFHYKGGRVKCEIGLAKGKKLHDKRETEKKRDWEREKARIMRSAT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: P24D7_ARATH
Sequence: MNHRRSSIVLLILSILSPVTLSIRYELLSGHTKCISEEIHANAMTIGKYSIINPHEDHPLPSSHKVTVRVTSPQGTAYHESDGVESGQFSFVAVETGDYISCFSAVDHKPETTLIIDFDWRTGIHTKDWSNVAKKSQVETMEFEVKKLFETVNGIHDEMFYLRDREEEMHNLNIATNSKMAWLSFVSLAVCLSVAGLQFWHLKTFFQKKKLI
What is the function of this protein?
Involved in vesicular protein trafficking.  Mainly functions in the early secretory pathway.  Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side (By similarity).
What are the official names of this protein?
Transmembrane emp24 domain-containing protein p24delta7, p24 family protein delta2a, p24delta2a, p24 family protein delta7, p24delta7.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Note=Cycles between the endoplasmic reticulum and Golgi via COPI and COPII dependent pathways.
Protein: RECO_STAAC
Sequence: MLMRQKGIIIKAVDYGESDKIITILNEHGAKVPLMARRAKKVKTGLQAQTQLFVYGLFIYNQWRGMGTLNSVDVISQHYKLQMDLYVSSYAALAAETIERSMDEGDIAPYNYQLLQFVLEKIESGTSAQLMSVVVMLKCMKRFGFTASFNRCAVSGNDTQADLIGYSFKFDGAISRQEASKDVHAVILSNKTLYLLDVLQKLPIDKMNSLNIHQEIIDEMSDIILMLYREYAGMFFKSQKLINQLKRLEQ
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: LDH_THEAQ
Sequence: MKVGIVGSGFVGSATAYALVLQGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVRSGWYEDLEGARVVIVAAGVAQRPGETRLQLLDRNAQVFADVVPKILKAAPEAVLLIATNPVDVMTQVAYRLSGLPPERVVGSGTILDTARFRALLAQHLLVAPQSVHAYVVGEHGDSEVLVWSSAQVGGVDLEAFAQARGRALTPDDRLRIDEGVRRAAYRIIEGKGATYYGIGAGLARLTRAILTDEKGVFTVSLFTPEVEGVEEVALSLPRILGARGVEATLYPRLNEEERQALRRSAEILKGAASALGF
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTSS2_XENTR
Sequence: MLRSDVRRVAAGRKASLDGLYCEELEVRGNRNLGNKFSHRGELRSSTESEVFDDGTNTFFWRAHTLTVLFILTCSLGYVTLLEETPQDTAYNAKRGIIASILVFLCFGVTQAKDGPFSRPHPAYWRFWLCVSVVYELFLIFILFQTVHDGRQFMKFIDPKLGVPLPERDYGGNCLIYDPGNKTDPYHNLWDKMDGFVPAHFLGWYIKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSECWWDHWIMDVLVCNGFGIYCGMKTLEWLSMKPYKWQGLWNIPTYRGKMKRIAFQFTPYSWVKFEWKPASSLRRWLAVCGIIFVFLLAELNTFYLKFVLWMPPEHYLVLLRLVFFVNVGGVAMREIYDFMDDLKFHKKLGQQAWMVAAITVTEFLIVVKYDPYTITLPLPFYVTQCWILGIVLVLTWTVWRFFIRDITLRYKEIRQQKQHRNEEEKSHRNGDVNSEKDTNKHKKH
What is the function of this protein?
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine (By similarity).  Catalyzes the conversion of phosphatatidylethanolamine and does not act on phosphatidylcholine (By similarity).  Can utilize both phosphatidylethanolamine (PE) plasmalogen and diacyl PE as substrate and the latter is six times better utilized, indicating the importance of an ester linkage at the sn-1 position (By similarity).  Although it shows no sn-1 fatty acyl preference, exhibits significant preference towards docosahexaenoic acid (22:6n-3) compared with 18:1 or 20:4 at the sn-2 position (By similarity).
What are the official names of this protein?
Phosphatidylserine synthase 2, PSS-2, PtdSer synthase 2, Serine-exchange enzyme II.
What is the protein family that this protein belongs to?
Belongs to the phosphatidyl serine synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Highly enriched in the mitochondria-associated membrane (MAM).
Protein: DYR1A_RAT
Sequence: MHTGGETSACKPSSVRLAPSFSFHAAGLQMAAQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWSLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFAAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS
What is the function of this protein?
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities (PubMed:8631952, PubMed:9748265, PubMed:18938227, PubMed:22998443).  Exhibits a substrate preference for proline at position P+1 and arginine at position P-3 (By similarity).  Plays an important role in double-strand breaks (DSBs) repair following DNA damage (By similarity).  Mechanistically, phosphorylates RNF169 and increases its ability to block accumulation of TP53BP1 at the DSB sites thereby promoting homologous recombination repair (HRR) (By similarity).  Also acts as a positive regulator of transcription by acting as a CTD kinase that mediates phosphorylation of the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A (By similarity).  May play a role in a signaling pathway regulating nuclear functions of cell proliferation (By similarity).  Modulates alternative splicing by phosphorylating the splice factor SRSF6 (PubMed:22767602).  Has pro-survival function and negatively regulates the apoptotic process.  Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1.  This in turn inhibits p53/TP53 activity and apoptosis (By similarity).  Phosphorylates SEPTIN4, SEPTIN5 and SF3B1 at 'Thr-434' (PubMed:18938227).
What are the official names of this protein?
Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Dual specificity YAK1-related kinase, Protein kinase minibrain homolog, MNBH, RP86.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: NTPPA_ACIAD
Sequence: MASSSPRRQELLKQLGLEFESYAPEIDESVQYNETVEAYVERLAREKANTILQQFPQSIIIAADTSLSIDGKIIGKPESKQHAFDIWSTLSGRRHDVFSGICVAASNAIHSCVVKTSVEFQTLSMADMELYWATGEPLGKAGAYAIQGIAAQFIPRIEGSYTNVVGLPLFETIQLLKRVKAFN
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNC_XYLF2
Sequence: MSMPQAILTDIEGTTSSLSFVKEVLFPYARRALPDFVREHREHPDVMPWLDQVANETGTAFSEEALVATLQTWIDTDSKHTALKALQGMIWTSGYQNGDFTAHLYPDAVQRLRAWHAANVPLYVYSSGSVPAQQLFFRHSHAGDLSGLFSGWFDTQIGGKRESTSYQRIAQHIGIAPAGIVFLSDVIEELNAAAQIGLNTVLIDRRDDYPTPRHLKDTDRHLHLDSFAQLPF
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: SYFB_CAMJE
Sequence: MIITKSWLNDWLELEEISSDKIAKTLNSIGIEVDRVGALKAPDKVVVGYVKEKIKHENSDKLSICQVDIGSETLQIVCGAANVDAGQFVAVATKGAIMSNGMEIKEAKLRGVDSCGMLCSSLELGFEKINEGIMLLDESIGKLELGRPLNTYEIFNDELIEVELTPNRGDCLSIYGIARDLAAALNLNLKEPKPFKESENVLGIGRILRLAAEKELNGLYNYRAIGLKEEIQTNLLLSLRLAQIEGLGKNSIENLLNYATHSTGVLFNAYDLSSFSEKDEEFTINLSKQVHGETKVSYKDKLLSFSGIFQNNESRCKDDSKIIIIEANYTDPLVIADAKIYHKDQDEKMLYRSFRGSEPKLNLGMDFLLGIFEQIPNLVIYSSSQQILTDKELPIIPISIEGISDIIGQNVDKDEVLKILKKLGFELILSGEGLINVKAPLHRPDIKNLSDICEEVVRIIGIDNIASKGLEFIEKNRLNSAYKNYIEFLNLRKRAVASGYFESLHYVLDNGEELKRLGFDSVKLKLINPITAELNTLRTTLLNHLLNAASLNAKNSKKIIKLFELGAVFNVNNQELNRIAFIHSGLKEEAKISNKAKPESVQFYDFLLDIKNIIGDFKLKSSKYNILSPYEQADIYLSDIKVGFIGRLHLKIENERDLPKTYICELDLDLIRQDFKIAKPYSKFPAITRDLSVLIPKGFEYNQIKNCIEELNLEILENFRLVDIYSDENLKEFYSITISFSFRDINKTLEDNQVNECMDKILNTLKNLGLDLR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTLQ_BACSU
Sequence: MAQIIKIHDYISRYELDPYHYINQFVRLKKERWLSLVEAAERQHEERQASAEEPEPVQKRKKFSLKRRKEEIKADIQEERHQWFEDEEDIHVRLPKSRVALASFYKRHLYDFQLKWASSTLSEISQLSNQVKQDRILRYLTQQLPDSYFIMYKPVLKIQQAAVELSIVIISPLEIYCVSFLEAEEDSVYIGSKNRFWDKKTASQTASVLNPGLSLFRTDSVVSKIVKEKQAEIPVRKLLLSRTSYIDYPEPPYGLEIADKRSAEEWIERQKKNTAPIKHHQVKAAKALLSYCMSDSYRRQEWLE
What are the official names of this protein?
Uncharacterized protein YtlQ.
Protein: LOLA_ENT38
Sequence: MKKIAIVGALLTSFVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGNAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATLLKDATSNTPFMLIARNQTSDWQQYNIKQNGDDFVLTPKTSNGNLKQFTINVSNNGTINQFSAVEQDEQRSSYQLKSQQNGAIDASKFTFTPPQGVTVDDQRNK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ILVC_AGRRK
Sequence: MRVYYDRDADLNLIKSKKVAIIGYGSQGRAHALNLKDSGAQNVVIALKAGSPTVKKAEADGFKVMTVAEAAGWADLMMMATPDELQADIYKADIAPNIRDGAAIAFAHGLNVHFGLIEPKASVDVVMIAPKGPGHTVRGEYQKGGGVPCLVAVHQNASGNALELALSYACGVGGGRSGIIETNFREECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEWGEYVTGPRIITEETKAEMKRVLKDIQTGKFTSDWMQEYRSGAARFKGIRRMNDSHQIEEVGAKLRGMMPWIGKNKLVDKSVN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ZN768_MOUSE
Sequence: MEREASSWGLESRDVHSPNAVGSPEGSLKDPAGNTSENEEGEISQREGNGDYEVEEIPFGLEPQSPEFEPQSPEFESQSPRFEPESPGFESRSPGFVPPSPEFAPRSPESDPQSPEFESQSPKYEPRSPGCHPRSPGCEPGSPRYEPKSPGYGSKSPEFESQSPGYESQSPGYEPQNSGDGVQNSEFKTHSPEFETQSSKFQEGAEMPLSPEEKNPLSISLGVHPLDSFTQGFGEQPTGALPPFDMPSGALLAAPQFEMLQNPLNLTGTLRGPGRRGGRARGGQGPRPNICGICGKSFGRGSTLIQHQRIHTGEKPYKCEVCSKAFSQSSDLIKHQRTHTGERPYKCPRCGKAFADSSYLLRHQRTHSGQKPYKCPHCGKAFGDSSYLLRHQRTHSHERPYSCPECGKCYSQNSSLRSHQRVHTGQRPFSCGICGKSFSQRSALIPHARSHAREKPFKCPECGKRFGQSSVLAIHARTHLPGRTYSCPDCGKTFNRSSTLIQHQRSHTGERPYRCAVCGKGFCRSSTLLQHHRVHSGERPYKCDDCGKAFSQSSDLIRHQRTHAAGRR
What is the function of this protein?
Binds to mammalian-wide interspersed repeat (MIRs) sequences in euchromatin and promoter regions of genes at the consensus sequence 5'-GCTGTGTG-[N20]-CCTCTCTG-3', consisting of two anchor regions connected by a linker region; the linker region probably does not contribute to the binding specificity (By similarity).  Required for cell homeostasis (By similarity).  May be involved in transcriptional regulation (Probable).
What are the official names of this protein?
Zinc finger protein 768.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CP1_ARATH
Sequence: MCPSGRIAIPITTTANPNFRPAFEIIDTDHDGKISSDDLRAFYAGIPSGENNDETMIGTMISVADANKDGFVEFDEFEKVLETTPFSRSGNGGDDGLMKDVFKVMDKDGDGRLSYGDLKSYMDSAGLAVTDDEIKSMIRLAGGDLNDGVSFDGLLKIFGC
What is the function of this protein?
Binds calcium in vitro.
What are the official names of this protein?
Calcium-binding protein CP1, NaCl-inducible Ca2+-binding protein, AtCP1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: FENR_LACPL
Sequence: MSAEYDLTIIGGGPVGMFAAFYAGMRNARVQLLESLPELGGQVQALYPEKIIHDVAGYPAIKGRELVAQLEKQLTQFPIDIQLASPVTDVTGAMGDFTITTASGQQSHSKAIIVATGSGAFEPRRLAVDNAAEFENKQLFYHIPSVKQFADRTVLVAGGGDSAIDMALMLEPVAKHVYIMHRRDRFRGMEHNVDLLKASSVEIKTPFLIKQLAETATGQLQLTMKEVRGTTEETLAVDDLIVNYGFIADNKVIRNWHVTPTMAHRLITVDTEMNTDVPGIAAIGDTVTYAGKLGLIASGFGEAPNAVNQLMMTLYPERRSPLHSTTVFEKM
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: IF1_BIFLO
Sequence: MAKDGVIEVEGQVVEALPNAMFRVELENKHIVLATISGKMRKNYIRILPQDRVVLEMSPYDLNRGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT5H_DROME
Sequence: MSDSEVSNMSDSGSEDGSISNKSQRSARSKSRSRSRSGSRGSRSVSRSRSRSQSGHSRSGSESPQRRDNRGKSDESGEEEEEPPGEDIDSEEYDEEENDDHPRKKKKKERFGGFIIDEAEVDDEVDEDDEWEEGANEIGIVGNEIDELGPTARDIEIRRRGTNLWDTQKEDEIEEYLRKKYADESIAKRHFGDGGEEMSDEITQQTLLPGIKDPNLWMVKCRIGEEKATALLLMRKYLTYLNTDDPLQIKSIIAPEGVKGYIYLEAYKQTHVKTCIDNVGNLRMGKWKQEMVPIKEMTDVLKVVKEQVGLKVKQWVRLKRGLYKDDIAQVDYVDLAQNQVHLKLLPRIDYTRMRGALRTTATESDDSKRKKKRRPAAKPFDPEAVRAIGGEVHSDGDFLLFEGNRYSRKGFLYKNFTMSAILSDGVKPTLAELERFEESPEEVNLEIMGTVKDDPTMAHSFSMGDNVEVCVGDLENLQAKIVAIDGTMITVMPKHQDLKDPLIFKASELRKYFKTGDHARVLAGRYEGETGLIIRVEPTRVVLVSDLTNHELEVLPRDLQLCSDVATGVDCLGQFQWGDMVQLDSQNVGVIVRLERENFHVLGMNGKCIECKPTALHKRKENRHTVALDADQNQIRRRDVVKVMEGPHAGRSGEIKHLYRSLAFLHCRMYTENGGIFVCKTRHLQLAGGSKTTVSNAGIVGGLGFMSPRIQSPMHPSGGRGARGGARGGRGGFRVTRDREILGKTIKISGGPYKGAVGIVKDATESTARVELHTSCQTISVDRNHIAIVGVTGKEGSVSTYGRTPARTPGYGAQTPSYTAAGSKTPLVGSQTPNWDTDTRTPYGTMTPSHDGSMTPRHGAWDPTANTTPARNNDFDYSLEEPSPSPGYNPSTPGYQMTSQFAPQTPGTLYGSDRSYSPFNPSPSPAPSPYPVGYMNTPSPSTYSPNTPGGIPQSPYNPQTPGASLDSSMGDWCTTDIEVRIHTHDDTDLVGQTGIIRTVSNGVCSVFLRQEDRSVSIVSEHLAPVLPCNGDEFKIIYGDDRESVGRVLSKDGDVFVCRINEEIKLLPINFLCKMKSID
What is the function of this protein?
Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.  DSIF enhances transcriptional pausing at sites proximal to the promoter, which may facilitate the assembly of an elongation competent RNA polymerase II complex.  DSIF may also promote transcriptional elongation within coding regions.  DSIF is required for the transcriptional induction of heat shock response genes and regulation of genes which control anterior-posterior patterning during embryonic development.
What are the official names of this protein?
Transcription elongation factor SPT5, DRB sensitivity-inducing factor large subunit, DSIF large subunit, dSpt5.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes predominantly to transcriptionally active regions of polytene chromosomes.
Protein: YPI1_MAGO7
Sequence: MASRQSRQQHTTSAPAASRTQTETSTPSQEQPPQDPTPEVRSQPAILRLRGVRASSGPSVRWAEGVVDNEGLGRKSSKVCCIYHPTKPVGESSDESSSDSSSDSGTDSDDSTRGKGKRKHRSGGGGGGKKHGEGDCHGHNHGHDHGSSSSSGGGGGARKKKKKRTPSPNAYEKMPKVKPRAPAPEGAPGASGQ
What is the function of this protein?
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.
What are the official names of this protein?
Type 1 phosphatases regulator YPI1.
What is the protein family that this protein belongs to?
Belongs to the YPI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BET12_ARATH
Sequence: MNFRRENRASRTSLFDGLDGLEEGRLRASSSYAHDERDNDEALENLQDRVSFLKRVTGDIHEEVENHNRLLDKVGNKMDSARGIMSGTINRFKLVFEKKSNRKSCKLIAYFVLLFLIMYYLIRLLNYIKG
What is the function of this protein?
Required for vesicular transport from the ER to the Golgi complex.  Functions as a SNARE associated with ER-derived vesicles (By similarity).
What are the official names of this protein?
Bet1-like SNARE 1-2, AtBET12, Bet1/Sft1-like SNARE 14b, AtBS14b.
What is the protein family that this protein belongs to?
Belongs to the BET1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: QUEF_YERPE
Sequence: MSSYQNHKALAELTLGKPTAYCDYYDATLLQAVPRSMNREPLGLYPDNLPFHGADIWTLYELSWLNSNGLPQVAVGEISLNADSINLIESKSFKLYLNSFNQTIFADKESVRMTLQRDLAACAQGNVSVALYDLDEITGQPISNFNGECLDKQDIRIDSYEFNADYLQGAAGKDHVEESLVSHLLKSNCLITHQPDWGSVQIHYRGPQIDHEALLRYLVSFRHHNEFHEQCVERIFNDIMRFCQPETLTVYARYTRRGGLDINPWRSNTDFVPLTGRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP13_SOYBN
Sequence: MSLIPSIFGGRRSNVFDPFSLDVWDPFKDFHFPTSLSAENSAFVNTRVDWKETPEAHVFEADIPGLKKEEVKVQIEDDRVLQISGERNLEKEDKNDTWHRVERSSGNFMRRFRLPENAKVEQVKASMENGVLTVTVPKEEVKKPDVKAIEISG
What are the official names of this protein?
17.5 kDa class I heat shock protein, HSP 17.5-M.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_PIPCE
Sequence: MISIALEHVLTHISFSIISIVISVHLIKFLVPEIIGLCDSLEKGIITTSFCITGLLIIRWVYSRHLPLSNLYESLMFLSWGFSTIHIFSKIWNHQNDLSTITATGAIYCQAFATSGILNEMHQSAILVPALQSQWLMMHVSMMLLSYGALLCGSLLSVSLLVITFRKNIEILEKMNQFSFLIESFLLSEVRPLKKKKSFLQNISFLSFKNYHKYQFTQQLDHWSYRIINLGFTLLTIGILSGAVWANEAWGSYWNWDPKETWAFITWTIFATYLHTRTNQRMPGMHSAIVASIGFLIIWICYFGVNLLGIGLHSYGAFTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.