PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_NOCFA
Sequence: MTRARSYEIRTFGCQMNVHDSERLSGLLEDAGYVKAAPGATADLVVFNTCAVRENADNKLYGTLGHLAPVKAGRPGMQIAVGGCLAQKDRDTVVRKAPWVDVVFGTHNIGSLPVLLERARHNEQAQVEILESLEAFPSTLPAKRESAYAGWVSISVGCNNTCTFCIVPALRGKEVDRRPGDVLAEVQALVDQGVLEVTLLGQNVNSYGASFADPDEPRDRGAFAKLLRACGGIEGLERVRFTSPHPAEFTDDVIEAMAQTPNICPQLHMPLQSGSDRVLKAMRRSYRKARYLGIIEKVRAAMPHAAITTDIIVGFPGETEEDFQETLDVVRQARFTSAFTFQYSKRPGTPAAEMADQVPKQVVQERYDRLIALQEEISLAANRELIGTEVELLVAEGSGKKNAATARMSGRARDGRLVHFRPGGTAEPIRPGDLVTVDITEAAPHHLIADAPVKTHRRTRAGDAHERGITPKTAPIGVGLGLPRIGAPAPEPVAAGCSTGCGA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_PAVHV
Sequence: MSKESGKWWESDDKFAKAVYQQFVEFYEKVTGTDLELIQILKDHYNISLDNPLENPSSLFDLVARIKNNLKNSPDLYSHHFQSHGQLSDHPHALSSSSSHAEPRGENAVLSSEDLHKPGQVSVQLPGTNYVGPGNELQAGPPQSAVDSAARIHDFRYSQLAKLGINPYTHWTVADEELLKNIKNETGFQAQVVKDYFTLKGAAAPVAHFQGSLPEVPAYNASEKYPSMTSVNSAEASTGAGGGGSNPVKSMWSEGATFSANSVTCTFSRQFLIPYDPEHHYKVFSPAASSCHNASGKEAKVCTISPIMGYSTPWRYLDFNALNLFFSPLEFQHLIENYGSIAPDALTVTISEIAVKDVTDKTGGGVQVTDSTTGRLSMLVDHEYKYPYVLGQGQDTLAPELPIWVYFPPQYAYLTVGDVNTQGISGDSKKLASEESAFYVLEHSSFQLLGTGGTATMSYKFPPVPPENLEGCSQHFYEMYNPLYGSRLGVPDTLGGDPKFRSLTHEDHAIQPQNFMPGPLVNSVSTKEGDSSNTGAGKALTGLSTGTSQNTRISLRPGPVSQPYHHWDTDKYVPGINAISHGQTTYGNAEDKEYQQGVGRFPNEKEQLKQLQGLNMHTYFPNKGTQQYTDQIERPLMVGSVWNRRALHYESQLWSKIPNLDDSFKTQFAALGGWGLHQPPPQIFLKILPQSGPIGGIKSMGITTLVQYAVGIMTVTMTFKLGPRKATGRWNPQPGVYPPHAAGHLPYVLYDPTATDAKQHHRHGYEKPEELWTAKSRVHPL
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 20 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1 (PubMed:15289612).  The capsid encapsulates the genomic ssDNA (Probable).  Binds to erythroid progenitor cells expressing high levels of P antigen and uses host ITGA5-ITGB1 and XRCC5/Ku80 autoantigen as coreceptors on the cell surface to provide virion attachment to target cell (PubMed:12907437, PubMed:8211117, PubMed:16076874).  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (PubMed:22718826).  Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region (PubMed:17020940).  The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (PubMed:11702787).
What are the official names of this protein?
Minor capsid protein VP1, Coat protein VP1.
What is the protein family that this protein belongs to?
Belongs to the parvoviridae capsid protein family.
What are the subcellular locations of this protein?
[Isoform Minor capsid protein VP1]: Virion. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Isoform Major capsid protein VP2]: Virion. Host nucleus. Host cytoplasm.
Protein: SYE_STREM
Sequence: MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFVIRIEDTDRKRHVEDGERSQLENLRWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKAYKSYVTEEELAAERERQEAAGETPRYVNEYLGMSADEKAAYIAEREAAGIVPTVRLAVNEAGIYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGDDHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYMPEAVFNFIALLGWNPGGEAEIFSREQLIALFDESRLSKSPAAFDQKKMDWMSNEYFKHADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAKEKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRIAVSGEMHGPELPNTIYLLGREQSIEHIANML
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLPG_BORBU
Sequence: MKIINILFCLFLLMLNGCNSNDTNTKQTKSRQKRDLTQKEATQEKPKSKSKEDLLREKLSDDQKTQLDWLKTALTGVGKFDKFLENDEGKIKSALEHIKTELDKCNGNDEGKNTFKTTVQGFFSGGNIDNFADQATATCN
What is the function of this protein?
An outer membrane protein that may participate in pathogenesis.  Some human Lyme disease patients have antibodies against this protein (PubMed:10948116).  The Mlp proteins probably undergo intragenic recombination, generating new alleles (Probable).
What are the official names of this protein?
Lipoprotein MlpG.
What is the protein family that this protein belongs to?
Belongs to the Multicopy lipoprotein (Mlp) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GPR20_HUMAN
Sequence: MPSVSPAGPSAGAVPNATAVTTVRTNASGLEVPLFHLFARLDEELHGTFPGLWLALMAVHGAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGARGCLRCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAGAVTLSVLGVTGSRPCCRVFALTVLEFLLPLLVISVFTGRIMCALSRPGLLHQGRQRRVRAMQLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFVTSGFQATVRGLFGQHGEREPSSGDVVSMHRSSKGSGRHHILSAGPHALTQALANGPEA
What is the function of this protein?
Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.
What are the official names of this protein?
G-protein coupled receptor 20.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
Protein: SECB_RALSO
Sequence: MSDQQQQQPGQDGQPFFNIQRVYLKDLSLEQPNSPHIFLEQEQPTVEVQVDVAATQLAEGVFEVTVIGTVTTKVKEKVAFLVEAKQAGIFDIRNVPVEQMDPLLGIACPTIVYPYLRSNIADTIGRAGFQPIHLAEINFQALYEQRLASAMEEAQAAGGNGGIVMPDGSKATH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_CLOPE
Sequence: MYMKKFNKVILAYSGGLDTSIIIPWLKENYGCEVIAVVGNVGQSDELVGLKEKAIKTGASKIYIEDLTKEFVEDYIFPTIQAGAKYEGKYLLGTSFARPIIAKRLVEIAKLEGADAICHGCTGKGNDQVRFELAIKTFNPEMQIIAPWRTWEIKSREEEIQYAIDNEVPINITYETNYSKDKNLWHLSHEGLDLEFPENEPKYDKILELCNTLEKAPNEAEYITLGFEKGIATSLNGEKLDGVTLLQELNKIGGKHGIGVIDMVENRLVGMKSRGVYETPGGSILYKAHKDLEELCLDKETSHYKEIVSLKFADLVYNGQWFTPLREALSAFISKTQETVTGEIKLKLYKGNIINAGMTSPYSLYSEEYATFGEDGIYNQKDAEGFINLFSLPSIVQAKMAQKLN
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_BURO0
Sequence: MSASDLTSVQAAAPQGSRQILVTSALPYANGQIHIGHLVEYIQTDIWVRTLRMHGHEVYYIGADDTHGTPIMLRAEKEGLTPKQLIDRVWTEHKRDFDSFGVSFDNFYTTDSEENRVLSENIYLALQEAGLIAEREIEQAYDPVKEMFLPDRFIKGECPKCHAKDQYGDSCEVCGSTYLPTELLNPYSVVSGATPVRKTSKHYFFRLSDPRCESFLREWVSGLAQPEATNKMREWLGDAGESKLADWDISRDAPYFGFEIPGAPGKYFYVWLDAPVGYYASFKNLCERNGIDFDAWIRPGSKAEQYHFIGKDILYFHTLFWPAMLEFSGHRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSYIDTGLNPEWLRYYFAAKLNATMEDIDLNLDDFQARVNSDLVGKYVNIASRAAGFLIKRFDGRVQDSAMNHPLVAKLRDAIAQIAASYEAREYGRALRHTMELADEVNAYVDGAKPWDLAKDPANAVALHETCSVSLEAFRLLSLALKPVMPRVAEAVEAFFGIAPLAWADAAKPLSSAQPIKAYQHLMTRVDAKQIEALLAANRDSLQAEAAGAAAAGANAAKDAKSNAKAKPAAVNGADDAPISIDDFAKIDLRIAKIVACQAVEGSDKLLQLTLDVGEEKTRNVFSGIKSAYQPEQLVGKLTVMVANLAPRKMKFGLSEGMVLAASATDEKAEPGLYILEPHSGAKPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
Protein: PE23_MYCBO
Sequence: MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAEDEVSTAIASIFGAYGRQCQVLSAQASAFHDEFVNLLKTGATAYRNTEFANAQSNVLNAVNAPARSLLGHPSAAESVQNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPLPSAGAGLAQVVNGVVTAGQGSAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVVGVVQAGGTFLTAGTSAATGLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLFSPAFLLAVPTALGGVGSLAIAVVQLVQGVQHLSLVVPNVVAGIAALQTAGAQFAQGVNHTMLAAQLGAPGIAVLQTAGGHFAQGIGHLTTAGNAAVTVLIS
What are the official names of this protein?
Uncharacterized PE family protein PE23.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDB4X_HETPE
Sequence: ILGKFCDEIKRIV
What is the function of this protein?
Amphipathic peptide with antimicrobial activity.
What are the official names of this protein?
Peptide Hp1478.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: PAX_I02A2
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKSDYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPKEAKRQLKKDLKLQEPCAGLPTKVSHRTSPALKTLEPMWMDSNRTAALRASFLKCQKR
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: BIOF_XYLFM
Sequence: MTRPDLNERILSLRKLRLAQCRTRTRRTIERRNGVRLEINGSWLVEFCSNDYLGLAQHFEIIAALQDAAARNGIGATASHLICGHHAIHKALEYELAEWLGYPRALLFGSGFTANLAVQQALLTKENDICVQDRLNHASLIDATRLAGCRLRRYPHLDVDGAAHQLKNAPEGAAMLATDGIFSMDGDIAPLRALSLVARTQQALMYVDDAHGIGVTGPQGRGCIAAAWLSVEEVPLQLVTLSKALGGYGAAVLGSATLIQHLAETARPYIYTTALPPAQAAAALTAIRIARRDEWRRQRLQELVERFRENSRRHGLEIMDSETPIQPLQCGDETTTMAMSAALEREGFLVNAIRPPTVPEGKSRLRVTLSALHTTEQIDTLVQALARSRDTLATEAAPVQV
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RBL_OSTTA
Sequence: MAPQTETKTGTGFQAGVKDYRLTYYTPDYQVKETDILAAFRMTPQPGVPAEECGAAVAAESSTGTWTTVWTDGLTQLDRYKGRCYDLEPVPGEDNQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPVAYCKTFQGAPHGIQTERDKLNKYGRGLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEAIYKSQAETGEIKGHYLNATAGNVDQMLKRAQVAKELGMPIIMHDYLTAGFTANTTLATYCREEGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRLSGGDHLHSGTVVGKLEGERNVTLGFVDLMRDAYVEKDRDRGIYFSQDWASLPGVMPVASGGIHVWHMPALVEIFGDDACLQFGGGTLGHPWGNAPGASANRVALEACTQARNEGRDLAREGGDVIRAACKWSPELAAACEVWKEIKFEFDTVDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLMM_CHLTA
Sequence: MTRDVRQLFGTDGVRGRANFEPMTVETSVLLGKAVAGVLLEKHAGKHRVVVGKDTRLSGYMFENALIAGLTSMGIETLMLGPIPTPGVAFITRAYRADAGIMISASHNPYRDNGIKIFSSDGFKIGQAVEERIEAMVASKDFGKLPDDHAVGKNKRVKDATGRYIEYAKATFPKGRTLKGLRIVLDCAHGATYRVAPSVFEELDAEVICYGCEPSGCNINAGCGALWPSTIQKAVIEHKADVGIALDGDGDRLIMVDEKGHIVDGDMLLSICASDLKRRQALSDNRVVATVMTNFGVLRYLESLGIQVTISPVGDRHVLQHMLENQAVLGGEQSGHMIFLDYNTTGDGIVSALQVLRIMIESESTLSDLTACIAKSPQALINVPVTKKVPLESLANVQGVLKEVKEVLGDSGRILLRYSGTENICRVMVEGTKKHQVDSLAKTIVDVVEAEIGAEISE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL30_BURO0
Sequence: MSEKTVKVQLVKSLIGTRESHRATVRGLGLRRLNSVSELQDTPAVRGMINKVSYLVKVIA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: MSRB_TERTT
Sequence: MSDHNLKDDDYWRSKLTDEEFRICREKGTEMPFSGKYVDTTEAGTYLCRCCNTPLFKSLAKFDAGCGWPSFFEPLEKGVITEEMDTSLGMVRTEIMCEACGCHLGHVFTDGPQPTGLRYCVNSASIQFEEEKNQS
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: RS2_CAUVN
Sequence: MALPEFSMRQLLEAGAHFGHQTHRWNPKMDRYIFGSRSNIHIIDLSQSIPLLHQALVKVREVAAAGGRVLFVGTKRQASDPVATAAKRCAQYYVNHRWLGGTLTNWRTVSGSIARLRELEGVLAGEGQGRSKKELLQLTRERDKLELSLGGIKDMGGIPDIMFVIDTNKEAIAILEARKLNIPVVAILDTNCDPDGITYPIPGNDDAARALQLYCDLIADAVLDGLAAGQAAAGVDLGASVAPVEPALARELAPEAPAAEAAPESAEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y3198_SHEHH
Sequence: MPSMDIVSEVNEVELRNAVDNSVRELKGRFDFRGKEASIEYKDHIVTLTAEDDFQCRQLVDILRMQMSKRDVDPKSMDVDEKAVHSGKTFSLKVKFKEGIETLVAKKLVKLIKDSKLKVQSSIQGDSVRVTGKKRDDLQQVMALARESELGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein Shal_3198.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: CCDC7_MOUSE
Sequence: MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKYDMKICYLFIPQLVKMYLNHGLF
What is the function of this protein?
May play a role in tumorigenesis.
What are the official names of this protein?
Coiled-coil domain-containing protein 7, Protein BIOT2.
Protein: TBC14_MOUSE
Sequence: MTDGNLSTSMNGVALMGILDGRQGDSLQDLQHLSIKAAPRSLSVPEYGPSLKLGALEDRHSLQSVDSGIPTLEIGNPEPVPCSVVHVKRKQSESEIVPERAFQSACPLPSCTPSAPTCSEREQVVRKSSTFPRTGYDSVKLYSPTSKALSRSDNVSVCSVSSLGTELSTTLSVSNEDILDLMVTSNSSAIVTLENDDDPQFTDVTLSSINETSDLHQQDCVAETEEGRKLKLLHPFSHFFTRNLLARKQNARLDRQRDLGWKLFGKVPLRETAQKDSKKTQKEYEDKAGRPSRPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVLQAKKRELKEAQRRRKQLEERCKVEESIGNAVLTWNNEILPNWETMWCSKKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTADIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTRMDFIHSAQFLTRLPEDLPADEVFAAISTVQMQSRNKKWAQVLSALQKDSREMEKGSPSLRH
What is the function of this protein?
Plays a role in the regulation of starvation-induced autophagosome formation.  Together with the TRAPPIII complex, regulates a constitutive trafficking step from peripheral recycling endosomes to the early Golgi, maintaining the cycling pool of ATG9 required for initiation of autophagy.
What are the official names of this protein?
TBC1 domain family member 14.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Golgi apparatus, trans-Golgi network. Note=After amino acid starvation, Golgi apparatus-associated protein levels increase compared with fed conditions. May be cycling between the Golgi apparatus and an endosomal pool, redistributing to the Golgi apparatus upon starvation.
Protein: RPIA_BURO1
Sequence: MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSIATTERLKSHGIKVFDLNEIESLQVYVDGADEIDAGGAMIKGGGGALTREKIVASVADTFVCIADASKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVLRVTKDGAPYITDNGNEIIDVKGLQIADPRGFEAQVNAWPGVVTVGLFAERGANLCLLGTENGVETIVYPAG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SECA_HAHCH
Sequence: MFSSIARKIFGSKNAREIKRMGKVVKRINELEESISALDEAALKAKTQEFRSRLEKGETLEQLLPEAFAVAREAGKRVMGMRHFDVQLIGGMVLHEGKIAEMRTGEGKTLVATLPVYLNALSGKGVHVVTVNDYLARRDADWMRPLYEYLGLSVGVVVSGQDGETKRAAYASDITYGTNNEFGFDYLRDNMAFSLTDKAQRGQHFAIVDEVDSILIDEARTPLIISGPAEDSSELYRKINELVPQLKKGEPPEEGQPVDGHFTVDEKSRSVELSESGHTYVEELLTKNGLLEEGDSLYAATNLGLLHHISSALRAHHLYSKDVDYIVQNGQVVIVDEHTGRTMPGRRWGEGLHQAIEAKERIKIQAESQTLASTTFQNYFRLYEKLAGMTGTADTEAFEFRQIYGLDVIVIPTNKPIKRIDYNDLVYLSVDEKFQAVIDDIKDTVTQNRPVLVGTASIEASEYLSAMLKKEGIAHNVLNAKQHEREAHVIAQAGRPGAVTIATNMAGRGTDIVLGGNWEADVAELEDPTPEQIAKIKADWQKRHDQVIAAGGLHVVGSERHESRRIDNQLRGRSGRQGDPGSTRFYLSLEDNLMRIFASDRVKNIMQALGMQKGEAIEHRMVSNAIEKAQRKVEGRNFDIRKSLLEYDDVANDQRHVVYEQRNEIMATDDISEMIDAIRGDVVSATVSQFIPPQSIAEQWNVPGLEKQLESDFGVDLPVQQWLDEDKRLHEETLREKILQAVVDSYREKEEVVGASVMRNFEKQVFLQVLDTLWKEHLSNMDLLRMGIHLRGYAQKNPKQEYKREAFELFQNMLDTIKHDVVRVICHVRVQKQEEMEELERRRREALAQQMQRAQATHPEATEEDSDAEEQAEGSDAPYVRDHKKVGRNEPCPCGSGKKYKQCHGRLE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PIIL_ACHLY
Sequence: NDGNGRDSDPHDPGDWTTAGQCGLWQPARNSQHWTLV
What are the official names of this protein?
Protease 2 large chain, APII, Protease II large chain.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AUSJ_ASPCI
Sequence: MTTTRHRLLATASRFVTTLESLDVDAMLAVRSPTCLHHMCLPSFRNYSITNDQTREAFPQWKATITKYQFGILDDSQTLVDEQARKVMIRAKTAAETTVGDYNNEYVFILRMTEDCDTVDEIWEFYDSLRLRDLHHRLEGGHVPIGVDAPAPFTTTGSNSLDRSK
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of calidodehydroaustin, a fungal meroterpenoid (PubMed:28233494, PubMed:29076725).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:28233494).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:28233494).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (By similarity).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (By similarity).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (By similarity).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (By similarity).  The cytochrome P450 monooxygenase ausG modifies austinolide to austinol (By similarity).  Austinol is further acetylated to austin by the O-acetyltransferase ausP, which spontaneously changes to dehydroaustin (PubMed:28233494).  The cytochrome P450 monooxygenase ausR then converts dehydroaustin is into 7-dehydrodehydroaustin (PubMed:28233494).  The hydroxylation catalyzed by ausR permits the O-acetyltransferase ausQ to add an additional acetyl group to the molecule, leading to the formation of acetoxydehydroaustin (PubMed:28233494).  The short chain dehydrogenase ausT catalyzes the reduction of the double bond present between carbon atoms 1 and 2 to convert 7-dehydrodehydroaustin into 1,2-dihydro-7-hydroxydehydroaustin (PubMed:28233494).  AusQ catalyzes not only an acetylation reaction but also the addition of the PKS ausV diketide product to 1,2-dihydro-7-hydroxydehydroaustin, forming precalidodehydroaustin (PubMed:28233494).  Finally, the iron/alpha-ketoglutarate-dependent dioxygenase converts precalidodehydroaustin into calidodehydroaustin (PubMed:28233494).
What are the official names of this protein?
Austinoid biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the trt14 isomerase family.
Protein: RM23_MOUSE
Sequence: MARNVLYPLYQLGGPQLRVFRTNFFIQLVRPGTAQPEDTVQFRIPMEMTRVDLRNYLEQIYNVPVAAVRTRVQHGSNRRRDHKNVRIKKPDYKVAYVQLAHGQTFTFPDLFPEKDPRSPEPLEEELPQQRQSSDLRCPGIPSWFGL
What are the official names of this protein?
39S ribosomal protein L23, mitochondrial, L23mt, MRP-L23, L23 mitochondrial-related protein.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UBC9_CAEEL
Sequence: MSGIAAGRLAEERKHWRKDHPFGFIAKPVKNADGTLNLFNWECAIPGRKDTIWEGGLYRIRMLFKDDFPSTPPKCKFEPPLFHPNVYPSGTVCLSLLDENKDWKPSISIKQLLIGIQDLLNHPNIEDPAQAEAYQIYCQNRAEYEKRVKKEAVKYAAELVQKQMLE
What is the function of this protein?
Accepts the ubiquitin-like protein smo-1 from the aos-1-uba-2 E1 complex and catalyzes its covalent attachment to other proteins with the help of an E3 ligase such as gei-17.  Required to sumoylate the ETS transcription factor lin-1, Polycomb protein sop-2, and intermediate filament proteins, such as ifb-1 (PubMed:15107848, PubMed:15689373, PubMed:24933177).  Required for embryonic development, fertility, vulval morphogenesis, inhibition of vulval cell fates, lifespan, and neuromuscular activity (PubMed:24933177).
What are the official names of this protein?
SUMO-conjugating enzyme UBC9, RING-type E3 SUMO transferase UBC9, SUMO-protein ligase, Ubiquitin carrier protein 9, Ubiquitin-conjugating enzyme E2 9, Ubiquitin-protein ligase 9.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus envelope.
Protein: RS17E_SULIA
Sequence: MGNIYTKDIKRIVKEIYNQYKDEIKDDYNTNKQIVVRYVDVKSKKVRNRIAGYLTRYYKIMKEKETSPTEEKEEISEEI
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.