PharMolix/UniProtQA huggingface dataset:
Protein: SECA_RHDSA
Sequence: MLQILFGDPNERKIGRYKQIVNRINALEEEFKQLTDKELQNRTAIFISDISKNADLDNVLPSAFAVAREASFRVLGLRHFDVQLIGGMILHEGKIAEMKTGEGKTLVAILPAYLNALCGYGVHIVTVNDYLARRDAEWVGQVPKFLGLSVGLIQEGMTQEERKNNYSQDITYTTNSELGFDYLRDNMAILLQDIVQRPFYFCIIDEVDSILIDEARTPLIISGAGETTEEKYVQASKVSLNLVKNLHYEVDEKARNILLTDSGIVESEKQLECKDLYNVQNPWASYIFNALKAKELFIKDVHYIVKDSEVIIVDEFTGRIMQGRRWSDGLHQAIEAKENVPTQNETQTLASITYQNFFLLYPKLSGMTGTAKTEEAELDKIYALEVTCVPTHRPMQRKDYSDLIYKNQYAKWKSIADECLDMHTLGRPVLIGTTSVEKSELLSSLLKEYGVPHNLLNAKPENIKREAEIIAQAGRKGAVTIATNMAGRGTDILLGGNSNYMAKNALNILLKEVPSKSSFTKNDPQLQSLHSFLLNKIESYEIDDDELETKISIACEKGFTEDALTITLRAAYQILIEKYSSLIKKEQGEVIALGGLHVIGTERHESRRVDNQLRGRAGRQGDPGSSRFFLSLEDNLLRIFGGDKIVNLMETLRVEEDVPIESMLLNKSLESAQKKVEAYYYDARKQLFEYDEVLNYQRLAIYSERRRILESNNLRDWVIQYAETTIEDYIEHYFDKKHSMPNSASEVLDKIEDLLGLPYDLDPMYFETLSTSEAKNFLYQQVRIAYDLKESQIDLIENGLMRELERSFLLQKIDSAWKEHLQQMNSLRESIGWRGYGQKDPLIEYKNEAYDLFTSMTTNIRHSVVYLIFRSQPILKN
What is the function of this protein?
Has a central role in coupling the hydrolysis of ATP to the transfer of proteins across the thylakoid membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein. Note=A minor fraction is associated with the chloroplast thylakoid membrane.
Protein: GLYA_MYXXD
Sequence: MENIRTLAEVDPEIARVLREETQRQEEGLELIASENFVSPAVMEAVGSVLTNKYAEGYPGKRYYGGCEVVDVAENLAIARAKDLFGADAVNVQAHSGSQANMGAFMALMKPGDTMLSLDLNSGGHLTHGATFNFSGKLYKVVHYGLTRDTETIDFAQVESLAKEHKPKVIVVGASAYPRTLDFAKFREIADAVGAAMLVDMAHIAGLVAAGVHPSPVPVADIVTSTTHKTLRGPRGGLVLSREPYAKAINSQIFPGIQGGPLMHVIAGKAVAFKEALSPEFKAYQRQIVANAKALAEALQRAGLRLTSGGTDNHLMLVDLRPKKLTGKVAEEVLDKAGITVNKNMIPFDPEKPMTTSGVRVGTPAITTRGMREAEMAVVGRLIGEALDAAQDDAALARIKGQVKELSQGFPLYASRLK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TWST1_CALJA
Sequence: MMQDVSSSPVSPADDSLSNSEEEPDRQQPQSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGSAGGGGGSSSGGGSPQSYEELQTQRVMANVRGRQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH
What is the function of this protein?
Acts as a transcriptional regulator.  Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction.  This interaction probably involves the basic domains of both proteins.  Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B.  Regulates cranial suture patterning and fusion.  Activates transcription as a heterodimer with E proteins.  Regulates gene expression differentially, depending on dimer composition.  Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression.  Heterodimerization is also required for osteoblast differentiation.  Represses the activity of the circadian transcriptional activator: NPAS2-BMAL1 heterodimer (By similarity).
What are the official names of this protein?
Twist-related protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: DDX55_DROME
Sequence: MSRKKWSSLDKPPLSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEILQRRHKETPWGPKEIGALVISPTRELARQISEVLAQFLEHEDLEHLNQQLIVGGNSIEEDIATLRRETPCILVCTPGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLPRQRRTGLFSATQTTEVTDLIRAGLRNPVLVSVKEKASVNTPARLQNFYRIVEPELKFVALLEFLSSPATVIGKVMVFFPTCACVEYWAEALPPLLPKRTVLGIHGKMKNKRANVVEKFRNTPQAVLLCTDVLARGLDVPEIEWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLLPSEDAYVHFLKINQKVELTKLLTEEAEDADREKKKLPAVLDQLHRLQAADKGVYDKGMRAFVSHVRAYTKHECSAILRLKDLDLGKMATAYGLLQLPRMPELKNYQGGGYVAPAFEVDLSKLTYKNAQKEQVRQKKMETYEQTGSWPGQKQHKKRVESWDQTKKAKLDAKSKKELRKAKKQRKKAAEAEASRSGKGKKRQQFSQEDLDELASDIRLFKRLKKNKISEEDFDKAMGIEGNND
What is the function of this protein?
Probable ATP-binding RNA helicase.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX55 homolog, DEAD box protein 55.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
Protein: RIBA_BURMA
Sequence: MTLVATATLPTRYGTFTSYAFRVAGGDAEHLALVMGDVAEQPSVLTRLHSECLTGDVFGSYRCDCGEQLDLSLRYIAAEGRGVLLYLRGHEGRGIGLSNKIRAYALQEQGRDTVEANLDLGLPDDAREYDSAAAILRILKVTSVRLMSNNPKKFDTLARHGIPVCERVALAVPVREENERYIRTKQLKFGHYYFDENE
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: CY561_MOUSE
Sequence: MEHSSASVPAALPYYVAFSQLLGLTVVAVTGAWLGLYRGGIAWESSLQFNVHPLCMVIGMIFLQGDALLVYRVFRREAKRTTKILHGLLHVFAFIIALVGLVAVFDYHKKKGYADLYSLHSWCGILVFVLYFVQWLVGFSFFLFPGASFSLRSRYRPQHIFFGATIFLFSVGTALLGLKEALLFKLGSKYSTFEPEGVLANVLGLLLVCFGVVVLYILAQADWKRPSQAEEQALSMDFKTLTEGDSPSPQ
What is the function of this protein?
Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles (Probable).  It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes (By similarity).
What are the official names of this protein?
Transmembrane ascorbate-dependent reductase CYB561, Chromaffin granule Cyt b561, CGCytb, Cytochrome b-561, Cytochrome b561.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Multi-pass membrane protein. Note=Secretory vesicle containing catecholamines and amidated peptides.
Protein: UBIA_ECO81
Sequence: MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUBP2_CHICK
Sequence: MEEVVAERSNLGGVRHILLVLSGKGGVGKSTISTELALSLRHSGKKVGILDVDLCGPSIPRMFKVQDNDVHQCDAGWVPVFVDQEKSISLMSIGFLLEKPDDAVVWRGPKKNALIKQFVADVAWGELDFLIVDTPPGTSDEHISTVEALRPYKPLGAILVTTPQAVSVGDVRRELTFCKKTGLRVLGIVENMSGFVCPHCSECTNIFSKGGGEELAKHAGVPFLGSVPLDPQLSQSLEEGRDFIQEFPKSSAFPALTRIAQQILDGALQRSS
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2, Nucleotide-binding protein 2, NBP 2.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFW_FRASN
Sequence: MSALTSQLEEFRRCSTAEQYFDLLDVDYDPRVVAVNRLHILRFFAEEIAGLHDGADAEVSPEVLLRDYRAALIRAYEAFTTATALDHRLFKVLKDRAPEPAGFVPMSEITVERPATTQTDEKGQQR
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: RL6_METTP
Sequence: MVEEVVRRLDIPDGVDVQISGRSVRVKGPKGELSRELWYPDIEIKREDSKILIRSVARKKQHLAMVGTIAAHIKNMIRGVTDGFEYRMRVVYSHFPIQVKVADGKVAISNFLGERKPRFATIVGDVNVEVGKDEILIRGMDKEAVGQTMANIEQATRVRGFDVRIFQDGIYLVEKR
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: EF1A_METMP
Sequence: MAKEKPILNVAFIGHVDAGKSTTVGRLLLDGGAIDPQLIVRLRKEAEEKGKAGFEFAYVMDGLKEERERGVTIDVAHKKFPTAKYEVTIVDCPGHRDFIKNMITGASQADAAVLVVNVDDAKSGIQPQTREHVFLSRTLGITQLAVAINKMDTVNFSEADYNEMKKMLGDQLLKMVGFNPDNIDFIPVASLLGDNVFKKSENTPWYNGPTLAQVIDGFQPPEKPTTLPLRLPIQDVYSITGVGTVPVGRVETGIIKPGDKVVFEPAGAVGEIKTVEMHHEQLPSAEPGDNIGFNVRGVGKKDIKRGDVLGHTTNPPTVAADFTAQIVVLQHPSVMTVGYTPVFHAHTAQIACTFMELQKKLNPATGEVLEENPDFLKAGDAAIVKLMPTKPLVMESVKEIPQLGRFAIRDMGMTVAAGMAIQVTAKNK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMJ_SALTI
Sequence: MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNAQIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVAEAANTPVALVFGRERVGLTNDELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAWLATQENGDAADHEETPYPLVDDLERFYGHLEQTLLSTGFIRENHPGQVMNKLRRLFTRARPESQELNILRGILASIEQQNKGK
What is the function of this protein?
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
What are the official names of this protein?
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ, tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase, tRNA Cm32/Um32 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST_POVWU
Sequence: MDKTLSRNEAKELMQLLGLDMTCWGNLPLMRTKYLSKCKEFHPDKGGNEEKMKKLNSLYLKLQECVSTVHQLNEEEDEVWSSSQVECTELCCNFPPRKYRLVGEVYGDVFEEYILKDWDICLKGFYYLCNCFYCFLDKRHKQKYKIFRKPPMWIECYCYRCYREWFGFEISAETFFYWKKIIFLTTMQGVGLTR
What is the function of this protein?
Promotes efficient viral genome replication by accelerating both G1 and S phase progression of the cell cycle.  Inhibits host PP2A by binding to the A subunit, thereby displacing lower affinity regulatory B subunit.  Inactivation of PP2A in turn results in the transactivation of cyclin A and cyclin D1 promoters.  Late during the infection cycle, ST may induce dephosphorylation of host MTOR, leading to the inhibition of cap-dependent translation.  May establish and maintain high levels of viral genomes during persistent infection in cell culture.
What are the official names of this protein?
Small t antigen, ST, ST-AG.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: ISPE_PAEAT
Sequence: MGERFHARTVRVKAPGKVNVSLSVGPLRPDGYHSVASVYLAVSLYEEVAATSTEAPGITVSISPDSTLDLDGVDIPLDQRNLAYKAAAIMAEMSEKPTGVHLEITKRVPVAGGMGGGSADAAATLLACDALWNSGLSREELAHLAAELGADVPFSLLGGTAVGLGVGDKLSPALAKAQMDWVLVFADYGLSTPDVFRTLDGLRDSEGVEIPEPVDVDPTILQALRKGDPETLSRVLINDLQRASITLAPQLRDTIGLGEARGALAGMVSGSGPTIALLARDSVSASVLAEELTHRGHNALAVHGPVPGARIISDTLL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CIPKC_ORYSJ
Sequence: MLMATVSPARREPTPQAVRASPMPSAAAALVRRGGGGSGGTVLGKYELGRVLGQGSFAKVYQARHLETDECVAIKVLDKEKAVKGGMVHLVKREINVLRRVRHPNIVQLFEVMASKTKIYFVMEYVRGGELFSRVSKGRLREDTARRYFQQLVSAVDFCHARGVFHRDLKPENLLVDENGDLKVSDFGLAAGPDQFDPDGLLHTFCGTPAYVAPEVLRRRGYDGAKADIWSCGVILFALMAGYLPFHDHNIMVLYRKIYNGEFRCPRWFSKDFTRLITRLLDANPKTRITVPEIIESDWFKKGYKPVKFYIEDDKLYNLSDDVLNLEPADPVPPPLGLAPPVPPPPQGDDPDGSGSESDSSVVSCPATLSTGESQRVRGSLPRPASLNAFDIISFSKGFNLSGLFEERGNEIRFVSGEPMSDIVKKLEEIAKVKSFTVRRKDWRVSIEGTREGVKGPLTIGAEIFELTPSLVVVEVKRKAGDNEEYEDFCNMELKPGMQHLVHQMLPAPNGTPVSEKVERSSSLQAPLTLKLIGTEGSMS
What is the function of this protein?
Involved in drought stress tolerance.  CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
What are the official names of this protein?
CBL-interacting protein kinase 12, OsCIPK12, OsPK7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: ATPB_MYRFG
Sequence: MRINPTTSGPGVSTLEEKNLGSIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESXLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: KA17G_MESMA
Sequence: QRQCERLRDCYKYCMSPKRCTYGTCYCEPSP
What is the function of this protein?
Blocker of potassium channels (Kv).
What are the official names of this protein?
Toxin BmKK16.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 17 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSX_SINMW
Sequence: MVRISLDVMGGDYGPEVVIPGAARALERHPDIKFVLFGQEARCTELLAKHPKLQASSTFHDCEIAVGMDEKPSQALRRGRGKSSMWKAIDAINAHEADVVVSAGNTGALMAMSVFCLRTMQGIQRPAIAAIWPTLKGESIVLDVGATIGADAQQLMDFALMGGAMARALFEVERPSVGLLNVGVEEIKGQEEVKEAGRLIREADIEGIEYYGFVEGDDIGRGTVDVVVTEGFSGNIALKAAEGTARQIAEYLRAAMSRTLLAKIGYIFAKSAFDRLREKMDPRKVNGGVFLGLNGIVIKSHGGADAEGFAAAIDVGYDMVKNGLKAKIEADLARYHGAQASEALPRA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RS19_METBF
Sequence: MAKKSSSRLPKRKGEYTYRGKTVSELQELSLEEFAELLPSRERRSIKRGFTDGQKKVLHEFKEGKKVRTHHRDLIILPEMIGQTIEIHNGKGFVSVDLQPEMIGHRFGEFAPTRSRVSHGSAGVGATRSSKFVPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NDK_SULIL
Sequence: MVMQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDIAEKLYDEHKGKSFFEELVNYVTSGPVVCMVIEGDDVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASDSIEKAQREMSLFFDKSDL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_LEGPA
Sequence: MSKPVNLVLLYGGKSGEHEVSLVSAASVLKHLDSEKYHIIPIAMDKSGRFHRHDYNDLLACSDKLPVVTEKSTPLEGLLINGRLAVDAEIVFPVVHGPLYEDGCLQGLLELAGVAYVGCDVLSSAIGMDKDMARRLACINGLKSARYKLLSWHANASERQQFCHEVASEFGWPLFVKPCSLGSSVGIHKANNMDELNAAVADALRYDEEILVEEFIVGREIELAVLENSIPCGKPRVSMVGEIKVNHPDGYYSYTAKYLESSQTDLIIPAQLNNSLEEQLKQAAANIFSYLKCKGMARVDFFVNDKTEEIYFNEINTLPGFTSISMYPKLWQATGVAYPDLLDELINLAMVHHNCRQHLVTNYL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MX2_ICTPU
Sequence: MSLSEQYEEKVRPCIDLIDSLRALGVEKDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKKSRKADFWHGKIKYEDYEEEIEDPADVEQMIRKAQNEIAGTGMGISDKLISLEVTSSNVPDLTVIDLPGITRVAVKDQPENIGDQSKRLIKKFITKQETINLVVVPCNVDIATTEALKMALEVDPNGERTFGVLTKPDLVDKGSEETVVSIINNEIVYLNKGYIIVRCRGQQEIKDRVSLNETVKRERDFFEDHPHFRTLYDNRKATIPNLAEKLTLELVFHIGRCLPRLEERIQVKLSETQAELDRYGSGTPTEPEQRIYFLTDKITAFIQDVLNLTTGEEVKSMLYMNIFPDLRKQFDLWKNDLDSVGETFNKKIEKEMKAYEEKYRGRELPGFLKYNTFEVIVKGQIKQLEEPAIRRLKEISDLIKREFSQLAHSNFPGFPNILKMAKTKIDNIKQVKESETESILRTQFKMEMMIYTQDKTHHDNLKMLKSKEEGKERQKLGVAHSPSHKLYDHSDSEGIREELTCHLKSYFSIVTKRLADQVPMVIRYMMLQESAAQLQREMIQLIQDRHNIEELLKEDHDIASKRNNLHSCQKRLTEALKYLAKF
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx2, Interferon-inducible Mx2 protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPCT_RAT
Sequence: MAGPAAHFSDEQFREACAELQKPALTGADWQLLVEASGITIYRLLDQSTGLYEYKVFGVLESCIPSLLADVYMDLDYRKKWDQYVKELYEKSFDGQMVAYWEVKYPFPLSNRDYVYTRQRRDLDVDGRKIYVVLAQNISVPQFPEKSGVIRVKQYKQSLAIESDGKKGSRVFMYYFDNPGGQIPSWLINWAAKNGVPSFLKDMVKACQNYHKKT
What is the function of this protein?
Lipid transfer protein that promotes intermembrane transfer of phosphatidylcholines but no other phospholipids.  Binds a single lipid molecule.  May play a role in hepatocellular selection and transport of phosphatidylcholines during bile formation.
What are the official names of this protein?
Phosphatidylcholine transfer protein, PC-TP, START domain-containing protein 2, StARD2, StAR-related lipid transfer protein 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSWB_TRYBR
Sequence: MWIILALLTLAGSRVAHGAGKNVNGVEFNLFCHIANMLNAEKIEDDKTDGLDRQAAEAWTAIDSIFTVTANESYYSEGPASAANTTDENQDAKPERVAKWVQKRNQIDKIAAPGNEKNGKYARRPRDRMSAATGAKLDTVFTLASEARVRLMQIDTEIATNKQEIRQQLGLHCSEGQGKGQSRNQHPDNAAFASDYSTACKGSTGPGKSLANDLVCICSTDTSQAQSTLQMCTSIDDANSLFSTLHKRSQCQGDFPCPHRVCAKTAETSELTETNINNCVTAFTATLGRHTKSSATNEGAYVFGSGQNSGDECNGGAATGQSCVSYHDLITAKSGTTLSGAITRLKQLQIAKAKLKARRLLLQNRERQQTRLMALADKMQELYQEALHDEVQLRKEAQNKPQETPDSDKQKACEKYHNKSKECKENGCQWSGTEETIGKCEAKPKAGTEAATTGPGERDAGATANTTGSSNSFVIKTSPLLFAFLLF
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein WRATAT B, VSG.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: PMP3_CANAX
Sequence: MNSEKIIEVIIAIFLPPVAVFMKCGATTPLWINLVLCIFIWFPAILHALYVVLKD
What is the function of this protein?
Plays a role in the regulation of membrane potential.
What are the official names of this protein?
Plasma membrane proteolipid 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0057 (PMP3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYRD_BURO1
Sequence: MFSSLYPLARASLFKMDAEDAHHLTLRALGAAGRTGLACALSARVPDAPRTVMGLTFRNPVGLAAGLDKDGAAIDGLAALGFGFIEVGTVTPRPQPGNPRPRMFRLPQAEALINRMGFNNHGVDQFVKNVQAARYRGILGLNIGKNADTPIERAAEDYLYCLERVYPFASYVTINISSPNTKNLRQLQGAGELDALLAALKDKQQRLADLHGKLVPLALKIAPDLDDEQVKEIGDTLLRHKIEAVIATNTTLSRAAVQGLPHADEAGGLSGRPVFDASNEVIRKLHAEVGNDVPIIGVGGIFSGEDAHAKLAAGAALVQLYTGFIYRGPALVSECVKAIARERSA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
Protein: HPRK_LACP3
Sequence: MADSVTVRQLVKATKLEVYSGEEYLDQRQVVLSDISRPGLELTGYFNYYPHERIQLFGRTEISFARNMSSEERLLILKRMATEDTPAFLVSRGLEAPAEMITAATAAHIPVLGSRLPTTRLSSLITEYLDSQLAERRSMHGVLVDIYGLGVLITGDSGVGKSETALELVQRGHRLIADDRVDVYQQDEQTIVGAAPPILSHLLEIRGLGIIDVMNLFGAGAVREDTTISLIVHLENWTPDKTFDRLGSGEQTQLIFDVPVPKITVPVKVGRNLAIIIEVAAMNFRAKSMGYDATKTFEKNLNHLIEHNEETDQNSSGDK
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.