PharMolix/UniProtQA huggingface dataset:
Protein: CH10_JANMA
Sequence: MNLRPLHDRVIVKRLDQETKTASGLIIPEAAAEKPDQGEILAIGNGKILEDGKVRPLDVKVGDRVLFGKYAGQTVKVDGNEVLVMREEDIMAIVQK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_MYCGA
Sequence: MRKNRAEKRKVLPDPVYNSVLVTRAINAIMLDGKKGIAQKILYGSFDLIAQKTQKDPLEIFNKAVENIMPRLELKVRRIAGANYQVPTDVSPERKVTLALRWLVTLSRKRHEKTMLDKIANEIIDASNNTGASVKKREDTHKMAEANKAFAHMRM
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MANB_CALSA
Sequence: MRLKTKIRKKWLSVLCTVVFLLNILFIANVTILPKVGAATSNDGVVKIDTSTLIGTNHAHCWYRDRLDTALRGIRSWGMNSVRVVLSNGYRWTKIPASEVANIISLSRSLGFKAIILEVHDTTGYGEDGAACSLAQAVEYWKEIKSVLDGNEDFVIINIGNEPYGNNNYQNWVNDTKNAIKALRDAGFKHTIMVDAPNWGQDWSNTMRDNAQSIMEADPLRNLVFSIHMYGVYNTASKVEEYIKSFVDKGLPLVIGEFGHQHTDGDPDEEAIVRYAKQYKIGLFSWSWCGNSSYVGYLDMVNNWDPNNPTPWGQWYKTNAIGTSSTPTPTSTVTPTPTPTPTPTPTVTATPTPTPTPVSTPATSGQIKVLYANKETNSTTNTIRPWLKVVNSGSSSIDLSRVTIRYWYTVDGERAQSAISDWAQIGASNVTFKFVKLSSSVSGADYYLEIGFKSGAGQLQPGKDTGEIQMRFNKDDWSNYNQGNDWSWIQSMTSYGENEKVTAYIDGVLVWGQEPSGATPAPAPTATPTPTPTVTPTPTVTPTPTVTATPTPTPTPTPTPVSTPATGGQIKVLYANKETNSTTNTIRPWLKVVNSGSSSIDLSRVTIRYWYTVDGERAQSAISDWAQIGASNVTFKFVKLSSSVSGADYYLEIGFKSGAGQLQPGKDTGEIQIRFNKSDWSNYNQGNDWSWIQSMTSYGENEKVTAYIDGVLVWGQEPSGTTPSPTSTPTVTVTPTPTPTPTPTPTPTVTPTPTVTPTPTVTATPTPTPTPIPTVTPLPTISPSPSVVEITINTNAGRTQISPYIYGANQDIEGVVHSARRLGGNRLTGYNWENNFSNAGNDWYHSSDDYLCWSMGISGEDAKVPAAVVSKFHEYSLKNNAYSAVTLQMAGYVSKDNYGTVSENETAPSNRWAEVKFKKDAPLSLNPDLNDNFVYMDEFINYLINKYGMASSPTGIKGYILDNEPDLWASTHPRIHPNKVTCKELIEKSVELAKVIKTLDPSAEVFGYASYGFMGYYSLQDAPDWNQVKGEHRWFISWYLEQMKKASDSFGKRLLDVLDLHWYPEARGGNIRVCFDGENDTSKEVVIARMQAPRTLWDPTYKTSVKGQITAGENSWINQWFSDYLPIIPNVKADIEKYYPGTKLAISEFDYGGRNHISGGIALADVLGIFGKYGVNFAARWGDSGSYAAAAYNIYLNYDGKGSKYGNTNVSANTSDVENMPVYASINGQDDSELHIILINRNYDQKLQVKINITSTPKYTKAEIYGFDSNSPEYKKMGNIDNIESNVFTLEVPKFNGVSHSITLDFNVSIKIIQNEVIKFIRNLVFMRALV
What is the function of this protein?
Degradation of hemicelluloses, the second most abundant polysaccharides in nature.  Contains two catalytic domains with mannanase and endoglucanase activities.
What are the official names of this protein?
Beta-mannanase/endoglucanase A.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glycosyl hydrolase 44 (cellulase J) family.
Protein: TRPD_METB6
Sequence: MTMKEAIATVVEGRDLAPAQAAAVMNMMMDGQATPAQIGGFLTALRAKGETPEEIAAFARVMREHTVHVKPRVSGTLVDTCGTGGDGAQTFNISTAAAFVAAGAGITVVKHGNRSVSSRCGSADVLTALGVDISVDPGRQAGIVQETGIIFLFAPSHHPAMKHVMATRQDLGCRTVFNLLGPLANPAGAAAQVLGVYDQKLTGPMAEVLSLLGVSRAMVVFGSGLDEITVTGETSVTELANSRITNYIVTPEQFGFTRAAPGDLLGGDPEKNARIIRAILDGAPGPARDIVLMNAGAAIYVGGRAATLAEGIRHAAESIDSGKAAGKLAALVTATRGAS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RL28_XANCP
Sequence: MSRVCQVSGKRVQTGNNVSHANNRTRRRFLPNLHERRFWVASENRWVKLRVSAHALRTIDKNGIDAVLKELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: KPRS_THEKO
Sequence: MFLLGSGGKHFEDELRNAGAKILEVEIKRFPDGEKYVRVMGNGDEATVVSSTFYPQDEKIVELLLLGDALREKGFEKLKLVVPYFAYSRQDRVTKDGEPISVRAVMRALGIYYEELYIFDTHNPETLRFFPGKAVNVSPARVIGEYFREKLGDGLVLAPDKGALERARAVAEVLGLEYSHFEKRRISPTEVEMHPVDVDVKGKNVLIVDDIISTGGTMVRAAELLRKLGAKKIYVSATHGVFAEGAIERVSRAVDELAVTNTIPTPVSRISIVPELLKLE
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).  It can also use CTP and GTP as substrates in addition to ATP.
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMP8_ARATH
Sequence: MEKTEESVGIRVYTTTTTQNPSPTSSRSPKPVPLSSLPMLPAGAAAGGGKGRKRRMVAKGVQKTVSKTSMLVNFLPTGTLLMFEMVLPTIYRDGDCNGINTLMIHLLLLLCAMSCFFFHFTDSFKASDGKIYYGFVTPRGLAVFMKPPSPGFGGGDVIAEKEIPVTDERYKLRVNDFVHSVMSVLVFMAIAFSDRRVTGCLFPGKEKEMDQVMESFPLMVGIVCSALFLVFPTSRYGVGCMST
What is the function of this protein?
Involved in membrane remodeling.
What are the official names of this protein?
Protein DMP8, AtDMP8.
What is the protein family that this protein belongs to?
Belongs to the plant DMP1 protein family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Vacuole membrane; Multi- pass membrane protein.
Protein: LON_RICBR
Sequence: MNKKSLPLMALRDIVVFPGVIAPVFVGRQKSLHALSNTTLSEEDNSKYILVTLQKKFDQENPNRNELYDVGILAKVIQIVKLPNTTAKILVEAIARVKISNIKGDEAFEANYEIIPDEEIFDANNMRSLVDNAVQLFAKYAGSDKKINAEIIETINKEISETSNFINIINILASHLITSLEEKQRLLEETSPFKRISTIINILTSNIVNSETEQALQQRVKKQIEKTQRDYYLHEQMKAIQKELDEDKSDLAEFDKKIKAAKLSKEAREKAEAELKKLRTMNQMSAESGVTRNYLETLLSLPWGKYDNSKIDINQAEKILNRDHFGLEKVKERIIEYLAVLQRSSKIRGPILCLIGPPGVGKTSLIKSIAEGMGRKYTKFALGGVRDEAEIRGHRKTYLGSMPGKILTQLKKVKTSNPVMLLDEIDKMGSDFRGDPASALLEVLDPEQNSHFVDHYLEVEYDLSNVIFIATANSYNLPRALIDRMEIIDISGYMEEEKIQIAKNYLVPKQLKMHKIKKDEITISDDAILDLIRYYTKESGVRSLEREIGALTRKALKQILADKKVKHISVDSNNLEEFLGARKYNFGLAEKNDQIGSTTGLAYTEVGGELLTIEALSFPGKGEIKTTGKLGDVMKESAMAAYSCFRSRAADFGLKYEDYKDFDVHIHVPAGAIPKDGPSAGCALFTTIVSLMTKIPVRRTVAMTGEVTLRGNVLPIGGLKEKLLAASRGGIKTVLIPEENVKDLKDIPPNIKSSLEIIPVSNIDQVLEHALTKKT
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_MARSD
Sequence: MQVAGKELEVQQGALCGEVLKEALSKKQFKNVVVAKCGDTLLDLTTTVPADCTDLEPVMADSKEGLEVIRHSTAHLMAEAVKKLFPTAKVTIGPSIASGFYYDFDYERPFTPEDLEAIEAEMLRRVGANEEFTREVLSSADALKKFEEMGEDYKIELINDLGEETVSVYTNGEFADLCRGPHVARTGMLKAFKLLSVAGAYWRGDENRQQLQRIYGTAFPDPKALKKHLAQIEEAKKRDHRKLGTQLDLFSVNPEVGAGMTIWHPKGALIRAILEDFERKEHLKRGYQFVQGPLILKRELWEKSGHYDNYRENMYFTEIDEQSYGIKPMNCLSHMLVFKSRLRSYRDLPQRYFEHGVVHRHEKSGVLHGLLRVRTFTQDDAHLICRPDQLRDEIIGVAKFVGDVMGLFGFEYEAEVSTKPEKAIGSDEDWDRATEALEGALKEMGMEYSINEGDGAFYGPKIDIIIKDALERRWQCATIQCDFTLPERFDLSYVGEDGERHRPVMLHRVILGSIERFIGVLLEHTGGALPAWLSPVQAKILTVTDSQNEFAQKVLQFLREKGIRAEVDDRNEKLGYKVREAQLEKIPYMLVIGDKEVAAESVNVRARDGEDPGLKSLEEAAELISTAIDEPFKRGGMSYSFS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REG9_PYRFU
Sequence: MAELLDRTDKMLLEELKKNARENIAALSKKLGIPRTTVHYRIKRLLEEGIIEKFTIKPNYKKLNLGTTAFVLIRYDPDSGLTQKEVAEQIAKIPGVYEVHIVAGEWDILLKVRAANAEEVGKIVIEKLREIKGVGQTVTMVSFVTIKEEI
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator PF0250.
Protein: ATPE_MEDSA
Sequence: MTLNLCVLTPNRTVWDSEVKEIILSTNSGQIGVLKNHAPIATALDIGILKIRLTNQQWVTMALMGGFARIGNNEITILVNDAEKSIDIDPQEAQQTLKIAEANLNKAEGKRQTIEANLALRRARTRVETILESINRF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RNZ_THEGJ
Sequence: MLQVIFLGSGGIMPTRERNVPAIALRYKGEIILFDVGEGTIRQMNSAKLSPMRVEKIFITHFHGDHYLGLGGLIQTMNLWNREKPLHIYGPKYTFEFVQNFLNSGFFRPGFEVHVHELGETRLKFKDYEIWSFKVEHGIPALGYVFKEKDKRGKFLPEKLAQYGLRPGPILGKLEKDGKIEWNGQVIRLEDVTGPRRRGVKVVYTGDTEPCERVRLFAERADLLIHDATYLSDGDRGDSYHSTVEEACETARRAKVKLLALFHRAFRYTYDEYLSGASKICQETGVNFVIPRDFDVLTYKSGEWKRENLLEEGK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: ATPE_NITMU
Sequence: MGVFHVDIVSAEESIYSGPAEFLVAPAEGGEVGIYPQHTPMLTRIKPGSVRIKAPLKEEELVYVSGGMLEIQPDIVTILADTAVRGADLDEAKAIEAKKHAEEAVRDRASTLDYARAQAELSEAIAQLAAIQKLRKRGH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL9_SULSY
Sequence: MKVVLTKDVEGWGTIGDVIEVKKGFARNYLIPRGLALELTEENKRFIDNILAQKARKLQREKEKAFELAKKLNGVEIEIERPIGVTGKMYGSVTTSDITEKLKEKELEVDKKKIMLRSPIRNLGSYNIQVKLHPEVSATIKVHVVPESK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PANE_ECOLI
Sequence: MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGTIEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVLPDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIEREGHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVPENTRLFEMVKRKESEYERIGTGLPRPW
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPA reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMD7_HUMAN
Sequence: MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKDRKEDKEKDKDKEKSDVKKEEKKEKK
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 7, 26S proteasome regulatory subunit RPN8, 26S proteasome regulatory subunit S12, Mov34 protein homolog, Proteasome subunit p40.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family.
Protein: AROA_CALS4
Sequence: MDVEVKKKNSLKGVISVPGDKSISHRAVMIGSIAEGLTEVENFLVAKDTLSTVECMRKLGVDIKLERNRVKVYGKGLYLSKSSEVLDVGNSGTTIRLLMGILAGQEFETILTGDDSIKRRPMGRVIVPLTLMGAKIEAREGNFAPVKIRGGKLRGIEYKMPIASAQVKSSIMLASLYAEGRTVIEEPALSRNHTELMLQTFGARIEIDGKKIFCYPGSKLKGQKIIVPGDISSAAYFIVAANLLPNSEVVIKDVNVNPTRTGIIDVLKGMGGNVELINERYVNNEKIADIVVKSSKLKGIEIGGDLIPKLIDEIPVIAVAAVFAEGTTVIKNAEELKVKESNRIKSMTSELGKMGAKIFETEDGMIIEGTGFLRGAEVESYNDHRVAMSLWIAGLLAEGRTIIKKAECVDVSYPDFYKTFDML
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_LACDA
Sequence: MKLYDLKAQGLDLQENIPLSRYTFTQTGGPAEYLAFPKTLAELKELLAAAKEDQLPITVIGNASNLIIRDKGIKGLVIILTEMKEIKVEADKVHAQAGARIIDTSFAAGEAGLSGLEFAAGIPGSVGGAVFMNAGAYGGETKDCLESATVVTRDGEVKTYTNAELHFSYRHSLLQENDEIVIAATFALKAGDKATILDQMNYLNALRSYKQPLEYPSCGSVFKRPTGHFVGPMLIKAGLQGKQIGGAQVSTKHAGFIVNKGGATATDYLNLIHYIQKTIKEKDGIALQTEVRIIGEE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_IDILO
Sequence: MSYASVVDVLTGKVAVDETVTVRGWVRTRRDSKAGISFINLHDGSCFDAIQAVVPAELPNYSNEVQKLTTGCSVAITGVVVPSQGKGQSFELQATKVHVYGWVEDPDTYPMAPKRHSMEYLREYAHLRPRTNITGAVMRVRNALSQAIHRFFHEEGYLWVSTPIITTSDCEGAGEMFRVSTLDMLNIPKTDKGEVDYSEDFFGKEAFLTVSGQLNVESYACSLSKVYTFGPTFRAENSNTSRHLSEFWMVEPELAFATLDDVAGLAEAMLKYVFKAVLEERPDDMAFFAERINSDAISRLEAIVNNDFVHMDYTDAIEILKNCDRKFEYAVEWGVDLQSEHERYLAEEHVGAPIILKNYPRDIKAFYMRQNEDGKTVAAMDVLAPGIGEIIGGSAREERLDILDQRIDEMNLPKEEYGFYRDLRRYGTVPHAGFGLGFERLVAYVTGVQNIRDVIPFPRAPKSAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOPC_BACSU
Sequence: MDLYRKAKRLKKELSKHEEINDSLKELAFDIFKELTVKPEFIDKNTNDVIGEEKINTSTFSNKERLDILIEWTIEIDPILSFIIDKCDIPIERTGGDDLDAFMENVYTEYIEELHKLPNRKSFDSSKITKIESFAQQITKTIELYLDGYVHLAYAEFDKGMNIFSEEVNIEELLLYNIDSIRIPCKFFRMRTSNTEVFSKDDMFHIPFEKRGIIRTNRFSIPGFPCLYLGSSSLVCWEELGRPDLNTTYTSVFHLEDEDIKILDLSVSPTELADNLKKFFEITFRRKIYKFNAYFMTWILISACLIRVKKQKDIFKPEYIIPQFLLEWVKQTESSEYWGICYLSSKINRQTIENYKLYKNYAIPVRQRKDSGHCSLLGETFQISDPVAWETFQSHKDSPESLPIKNPLFPETEGTHHDYHKTELGRLEAFLIRYRSVVKDQL
What is the function of this protein?
May be the toxic component of a type II toxin-antitoxin (TA) system.  Neutralized by its cognate antitoxin YopB.
What are the official names of this protein?
Putative toxin YopC, SPbeta prophage-derived protein YopC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MbcT/ParT/Res family.
Protein: EXT1A_DANRE
Sequence: MQAKKRYLILFSAGVCLILLFYLQGPASRRTPKRGDDPHPHWPHFSDPLRAFIPWDQTETEDYNVRASPRHKRDDSTGADKCRMDSCFDFELCKRNGFKVYVYPQQKGEKISESYQNILSSIEGSRFYTSDPGQACLFVLNLDTLDRDQLSPQYVHNLKTKIQNLNLWNNGRNHLIFNLYSGTWPDYTEDLGFDIGQAMLAKASISTESFRPNFDISIPLFSKDHPRTGGERGFLKYNTIPPFRKYMLVFKGKRYLTGIGSDTRNALYHIHNAEDVVLLTTCKHGKDWQKHKDARCDKDNAEYDRYDYKEMLHNSTFCLVPRGRRLGSFRFLEALQAACVPVMLSNGWELPFSEIIDWRTAAVIGDERLLLQIPSTVRSIHQDRILSLRQQTQFLWEAYFSSVEKIVLTTLEIIQDRVLQHSAHSTLMWNRLPGGLFTLPQYSSYLGDFPFFYALLGIKPHQKFTAVIHAVTPLVSQSQPIFKLLVAVAKSQFCAQIMVLWNCDKPLPSKHRWPATSVPVIVIEGESKVMSSRFLPYENIITDAVLSLDEDTVLSTTEVDFAFTVWQSFPERIVGYPARSHFWDSNKERWGYTSKWTNDYSMVLTGAAFYHRYYNYLYTHYLPGSLKGLVDQLSNCEDILMNFLVSAVTKMPPIKVTQKKQYKETMMGQTSRASRWADPDHFAQRQTCMNKFASWFGTMPLVHSQMRLDPVLFRDQVSILRKKYRDIERL
What is the function of this protein?
Glycosyltransferase required for the biosynthesis of heparan-sulfate.
What are the official names of this protein?
Exostosin-1a, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase 1a, Multiple exostoses protein 1 homolog a.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: TSAD_WOLSU
Sequence: MILSIESSCDDSSIAITRLEDRAILFHKKISQDSAHSPHGGVVPELASRLHAVALPKILEECAPFFPRLKAIAVTNEPGLSVTLLEGVMMAKALALALHLPLIAVNHLKGHLYSLFLEQESRFPLDVLLVSGGHTMVLHARSFGEIEIIGQSMDDSFGESFDKVAKMLSLGYPGGPIVESYAKEGDASRFPLPLPLAGKKEVAFSFSGLKNAVRLVIQSLQNPPNEQEKRDICASFQATAIAHLIQKCRLYLATSNAPYLAIVGGASANLALREEMERLGEHFGKKLLLAPLAYCSDNAAMIGRAALESYALGAFTSPLELTVRPRTPSLC
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AB17A_BOVIN
Sequence: MNGLSVTELCCLFCCPPCPGRIAAKLAFLPPEPTYSLVPEPEPGPGGAGAAPSGNLRALAGTPGRWKLHLMERADFQYSQRELDTIEVFLTKSSRGNRISCMYVRCVPGARYTVFFSHGNAVDLGQMSSFYIGLGTRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGISPDSIVLYGQSIGTVPTVDLASRYECAAVVLHSPLTSGMRVAFPDTKKTYCFDAFPNIEKVSKITSPVLIIHGTEDEVIDFSHGLALYERCPKAVEPLWVEGAGHNDIELYSQYLERLRRFISQELPSQRA
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins.  Has depalmitoylating activity towards NRAS.  Has depalmitoylating activity towards DLG4/PSD95.  May have depalmitoylating activity towards MAP6.
What are the official names of this protein?
Alpha/beta hydrolase domain-containing protein 17A, Abhydrolase domain-containing protein 17A.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD17 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Endosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendritic spine. Postsynaptic density membrane.
Protein: SPRTL_OCEIH
Sequence: MKLPSDIELFELVDKLSLTYFNKHFIDKVYFNTRLRTTGGRYLPSKRVIELNPKYVLESNKEEFYGIIKHELCHYHLHIEGKGYKHGDRDFKELLKATGSPRHCSPLPSQQREYRYKYQCIQCGFVYKRVRKVNMRKYRCGKCRGSLKEI
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP1_ARATH
Sequence: MALLSAMKLQGRPPPISSNLNPNSKPAGSDSVSLNASEPGSERKPRKFSSQLNRWNRARTLRSGAKLDSTITNGSNNTTGPMRPIESSSRTDVSTLDSDVSSSSNGVSEADMTAAKSIYIVSDGTGWTAEHAVNAALGQFDYCLVDRGCPVNTHLFSGIEDGEKLMEIIKQAAREGAMVIYTLADPSMAEATMRACKLWKIPSLDILGPITESISSHLGTNPSGLSRGITNSSLNEDYFKRIEAIEFTIKHDDGALPENLEKADIVLVGVSRTGKTPLSTYLAQKGYKVSNVPIVNGVDLPKTLFEIDPRKVFGLMINPLVLQGIREARAKSLGLGSSFKTKYSELGSVKEELELAKKIFAENPTWPVIEVTESAIEETAAVVLRLYDERQSNRAMPRISKSY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the dark/light-mediated regulation of PPDK by catalyzing its phosphorylation/dephosphorylation.  Dark/light-induced changes in stromal concentrations of the competing ADP and Pi substrates govern the direction of the reaction.  In the dark, phosphorylates the catalytic intermediate of PPDK (PPDK-HisP), inactivating it.  Light exposure induces the phosphorolysis reaction that reactivates PPDK.  Unlike the kinase function which can utilize either Thr or Ser as target, the phosphorylase function has a strict substrate requirement for threonyl phosphate.
What are the official names of this protein?
Pyruvate, phosphate dikinase regulatory protein 1, chloroplastic, Bifunctional dikinase regulatory protein 1, AtRP1, BFRP1, Pyruvate, Pi dikinase regulatory protein 1, PPDK RP1, PPDK regulatory protein 1.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: SPT4H_PONAB
Sequence: MALETVPKDLRHLRACLLCSLVKTIDQFEYDGCDNCDAYLQMKGNREMVYDCTSSSFDGIIAMMSPGDSWVSKWQRVSNFKPGVYAVSVTGRLPQGIVRELKSRGVAYKSRDTAIKT
What is the function of this protein?
Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II.  DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A.  DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter.  Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex.  DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II.  TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme.  Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT4, DRB sensitivity-inducing factor small subunit, DSIF small subunit.
What is the protein family that this protein belongs to?
Belongs to the SPT4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTPS_POERE
Sequence: MAESSGNPPAERIGYITRVQSFSACHRLHSLRLSDEENKEVYGKCNNPYGHGHNYKVEVTVRGKIDPVTGMVMNLTDLKKCIEEVIMIPLDHKNLDKDVPYFADVVSTTENLAVYIWDNMAKALPASLPYEIRIHETDKNIVVYRGE
What is the function of this protein?
Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases.  Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
What are the official names of this protein?
6-pyruvoyl tetrahydrobiopterin synthase, PTP synthase, PTPS.
What is the protein family that this protein belongs to?
Belongs to the PTPS family.