PharMolix/UniProtQA huggingface dataset:
Protein: Y2395_DROME
Sequence: MREVNLLNRFTRQFLFLIVLVTQICGVATFVYNSKAQCFRQSGFLRFYSSLVLIFLALFLIVTTSKMFHNLQAVWPYVVGSVIILVVRIHGLLESAEIVELLNQMLRIMRQVNLMARHPNLFRLKHLLLLLLALQNLLRSLNTIVGISNHSAEAYDSFLNSVILLIILAVLLSFLLQITINICLFVVLIATYSELHHCTRRISNDMDKLRLHSVHESGQFMVLVKQLQGITEKLIRLRQNVFHITVRIIRHFRFHWLCAIIYGLLPFFSLTAKDQNGFNFLIISALNIIFQWTIFAILSRESRITRSLCTFHLTNYHKETARTIDELLHQEIWERITVTIYGNTLDTKLLFKLLSISAFCAFVNRLEYLHI
What are the official names of this protein?
Uncharacterized protein CG32395.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROD_STRMU
Sequence: MKIVVPVMPQNIEEANQLDLTRIDSTDIIEWRADYLVKDDILTVAPAIFEKFSGHEVIFTLRTEKEGGNISLSNEDYLAIIRDIAALYQPDYIDFEYFSYRDVLEEMYDFSNLILSYHNFEETPENLMEVFSELTALAPRVVKIAVMPKNEQDVLDLMNYTRGFKTLNPNQEYVTMSMSKLGRISRLAADLIGSSWTFASLEQESAPGQISLADMRKIKEVLDAN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: ORC6_DICDI
Sequence: MDIEDVMNKLSLKNKKVLNRSSEYSRLIKVKRPMGLGPLEMCKPGACIFVACKELSIELNKSQLVRVLGTNDKLFEQSILALYTILGKKRPPYSIVEISNTFKLNSTICESSENLLKLYRTKILGGIEEVQSQFTNIDDGIFSAASVYIMTQQHSINIDHTLLLSLVDCSQETFQRAMNAITQCCYQGESIVKLKKTPPKNKQNTILRSPTSILISSSSTLNNTTTSTTTTAPKSPIPIPSLTPISQIKNLTTKPIVSPSSSPLLSSISPPKVLATPTLSSSSSSSSSSSSSLSPPLSSNPTTDLSSTNEPIVFNISSELLPIPPTTTFKNDGNENKNNTKNCNIEIIEEISNVDESPFNDNSVKKIEQSNPNISNKKRSRDELEKESELGKSQPPQPQQQPQQQQQQQKEKSVKNKINEGDLTLEQERLLIKKKKEQQFNDWKNSDFAKSKPTPVNATKQLTLDSFFK
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 6, Origin replication complex subunit F.
What is the protein family that this protein belongs to?
Belongs to the ORC6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL14_HELHP
Sequence: MIQSFTRLSVADNSGAKEIMCIKILGGSHRRYARVGDVIVASVKKAIPNGKVKKGQVVKAVVVRTKKEIHRENGSLVRFDDNAAVILDAKKEPIGTRIFGPVSREVRYANFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: BAT2_MYCRK
Sequence: MPATSMHQEDKQSANGLNLSPLERIKIEKHYGGGATLAFISNQHDELAQVLSRADILKIASYDCAAQALQAVLDCGPMLGKRGFSRADIVRIAGNGGGAQALYSVLDVEPTLGKRGFSQVDVVKIAGGGAQALHTVLEIGPTLGERGFSRGDIVTIAGNNGGAQALQAVLELEPTLRERGFNQADIVKIAGNGGGAQALQAVLDVEPALGKRGFSRVDIAKIAGGGAQALQAVLGLEPTLRKRGFHPTDIIKIAGNNGGAQALQAVLDLELMLRERGFSQADIVKMASNIGGAQALQAVLNLEPALCERGFSQPDIVKMAGNSGGAQALQAVLDLELAFRERGFSQADIVKMASNIGGAQALQAVLELEPALHERGFSQANIVKMAGNSGGAQALQAVLDLELVFRERGFSQPEIVEMAGNIGGAQALHTVLDLELAFRERGVRQADIVKIVGNNGGAQALQAVFELEPTLRERGFNQATIVKIAANGGGAQALYSVLDVEPTLDKRGFSRVDIVKIAGGGAQALHTAFELEPTLRKRGFNPTDIVKIAGNKGGAQALQAVLELEPALRERGFNQATIVKMAGNAGGAQALYSVLDVEPALRERGFSQPEIVKIAGNIGGAQALHTVLELEPTLHKRGFNPTDIVKIAGNSGGAQALQAVLELEPAFRERGFGQPDIVKMASNIGGAQALQAVLELEPALRERGFSQPDIVEMAGNIGGAQALQAVLELEPAFRERGFSQSDIVKIAGNIGGAQALQAVLELEPTLRESDFRQADIVNIAGNDGSTQALKAVIEHGPRLRQRGFNRASIVKIAGNSGGAQALQAVLKHGPTLDERGFNLTNIVKIAGNGGGAQALKAVIEHGPTLQQRGFNLTDIVEMAGKGGGAQALKAVLEHGPTLRQRGFNLIDIVEMASNTGGAQALKTVLEHGPTLRQRDLSLIDIVEIASNGGAQALKAVLKYGPVLMQAGRSNEEIVHVAARRGGAGRIRKMVALLLERQ
What is the function of this protein?
Binds to DNA in a sequence-specific manner.
What are the official names of this protein?
Burkholderia TALE-like protein 2, Modular DNA-binding domain protein BurrH2.
What is the protein family that this protein belongs to?
Belongs to the transcription activator-like effector (TALE) family. Bat subfamily.
Protein: PCKA_STAAW
Sequence: MSVDTYTETTKIDKLLKKPTSHFQLSTTQLYNKILDNNEGVLTELGAVNASTGKYTGRSPKDKFFVSEPSYRDNIDWGEINQPIDEETFLKLYHKVLDYLDKKDELYVFKGYAGSDKDTMLKLTVINELAWHNLFAKNMFIRPESKEEATKIKPNFTIVSAPHFKADPEVDGTKSETFVIISFKHKVILIGGTEYAGEMKKGIFSVMNYLLPMQDIMSMHCSANVGEKGDVALFFGLSGTGKTTLSADPHRKLIGDDEHGWNKNGVFNIEGGCYAKAINLSKEKEPQIFDAIKYGAILENTVVAEDGSVDFEDNRYTENTRAAYPINHIDNIVVPSKAAHPNTIIFLTADAFGVIPPISKLNKDQAMYHFLSGFTSKLAGTERGVTEPEPSFSTCFGAPFFPLHPTVYADLLGELIDLHDVDVYLVNTGWTGGKYGVGRRISLHYTRQMVNQAISGKLKNAEYTKDSTFGLSIPVKIEDVPKTILNPINAWSDKEKYKAQAEDLIQRFEKNFEKFGEKVEHIAEKGSFNK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1023_RICCN
Sequence: MRKLLLIITVFFTFNVAQASLPNIVASVNDEPITLNEFRARKKMIMALNNVESLTPAQDKQLSDLALKSLIDESLLFQYAGDREIPQEEIENAIKSIEDRNKMPHGSLLQYLKSRSVNPDSFISQIKSELIKMNILSSLSRSVQVSNKEIDVAILSSDQKDVEISMQVFTSKDGGNKAFTQMNNLKNRLKKCADVKKSLYDNFATMQIITDKLSKIEGVKQTIVKDLTPDKASNVFEVNNKFEITLVCSKKILNVNEDENNYVVNFLTNKKISQKAQKMFENMRKKAAIKIMLPS
What are the official names of this protein?
Uncharacterized protein RC1023.
Protein: AURC_CALAK
Sequence: MGAYSFRVIIVGGSITGMTLAHCLDRAGIDYVILEKHKDIFAEPGISIGLMPNGSRILEQLGIYSDVHALFEGIKKIYQYMPDGYCIETDSPVNIVDRFGLPFCVIDRYQFLKVLYSKFEDKSRFHMNKKVTSICHGKSDVSVTTADGETYHGDLVVGADGVHSVVRSEMWRIGNLARPGFVTEREKSELAAEFACVFGVAKAVPGQGRWEHILRYNEDFCFMFFPASGTDVFFNVIYKLNQKYVYPDIPRFTKEEGIEVCESVGDFPVWEDVKFRDIWAQRIAFTCVPLEEHMFKNWHHRRIICVGDSVSKMSPNMGQGGNTAIESAAALTNGLRKLVTSNYPDKPSERQLSNTLETFNRNQFKRLNTVHGDARYVTRLEALDGTLKRVFARYVMGHCGDLLVGNLARIVAGGGVLDFIPLTARSGKDWPPCPWQHSWGISESIDFCKKFAVASLIVLIVVLARALDSPAGLSSGIRSSSWSF
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of aurovertins, fungal polyketides that exhibit potent inhibition of adenosine triphosphate synthase (PubMed:26340065).  Tha biosynthesis starts with the HR-PKS aurA that selects propionate as the starter unit; synthesizes a hexa-ene chain through the repeated functions of the KR and DH domains in the first six iterations; selectively introduces three alpha-methyl substitutions at C4, C6, and C16 using the S-adensylmethionine-dependent cMET; and shuts off KR and DH in the last three iterations to afford a 1,3,5-triketo portion that can undergo intramolecular cyclization to yield the alpha-pyrone intermediate (PubMed:26340065).  AurE may act as a cyclase and enhances the rate of pyrone formation and product release of aurA (PubMed:26340065).  The methyltransferase aurB then methylates the C17 hydroxyl group (PubMed:26340065).  C17 methylation is required to initiate epoxidation by the downstream monooxygenase aurC (PubMed:26340065).  The monooxygenase aurC and the epoxide hydrolase aurD can iteratively transform the terminal triene portion of the methylated precursor into the dioxabicyclo[3. 2. 1]octane scaffold of aurovertin E.  Epoxidation modifications of the precursor occur in two separate steps; bis-epoxidation of the two terminal olefins takes place first, followed by another epoxidation that occurs at C7-C8 after tetrahydrofuran formation (PubMed:26340065).  The O-acyltransferase aurG converts aurovertin E to aurovertin A (PubMed:26340065).
What are the official names of this protein?
FAD-dependent monooxygenase aurC, Aurovertin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SNU13_KLULA
Sequence: MSAPNPKAFPLADATLSQQILDVVQQASNMRQLKKGANEATKTLNRGISEFIIMAADCEPIEILLHLPLLCEDKNVPYVFVPSRTALGRACGVSRPVIAASITTNDASAIKSQIYAVKDKIETLLI
What is the function of this protein?
Common component of the spliceosome and rRNA processing machinery.  In association with the spliceosomal U4/U6. U5 tri-snRNP particle, required for splicing of pre-mRNA.  In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs.  Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
What are the official names of this protein?
13 kDa ribonucleoprotein-associated protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YQGF_THEP3
Sequence: MRIMGLDVGDKTIGVAISDLSGTIAQGLTTIKRSSNKKDFERIKQIINEYEVGMIIVGLPKNMNGTLGPQGQKVMRFVEHLKEAFSIPIILWDERLTTVEAQRVLIEKADISRAKRKEVIDKLAAVLILQNYLDSQKNK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_BRASO
Sequence: MTTNDAGRIPSAAGGAELAALYRLLTWLSPAFPIGGFSYSSGLEWAVEAGDICDAAALRGWLATMLTDGSGFCDAAFLVHAHRATELDDIKRLSEVAELAAAFVPSRERQLETAAQGRAFIEIARSAWSCAGLDEAVAQCDVVVYPVAVGMVGALHGVPLEPLLHGFLHALVSNWISAGSRLVPLGQTDSQRVLAALEPVVVATADRSLHASLDDIGSATFRADLASLRHETQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_ANADF
Sequence: MKLILREDVENLGKGGELVDVKPGYGRNFLLPRGLAVLANPKNVRELEHQKAIATAKAAKMKASAQAVAKRLAETPITLSRKVGEQDKLYGSVTAMDVAEALAARGLQIDRRAIDLAEPIKTTGDFEVPVKLHSEVVGKVKVKVEAEAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YL446_MIMIV
Sequence: MNNSNTDNIIIINDSEPTYNLEDVINEIGDLLEDFDKIIDQYKQTIDQMVKKPKYVNLVLSGGSIRGISHIGVIKKLIDEELLDLSKMKAVAGVSAGAMLGLLIVLGFTIGEIWDFILNLDTKKIVDPDFMLILEKCGVERGRIIYDLIEDILTSKTDTKHINFKQLYEKTGIHFTVVGSCLTTKDVIYYDHINTPTFKVSVAVRISIGMPGFFTPIDIGGKKYIDGAVLNNYPMNLFAKELDKTIGILICNEHNTNYKYFEEYFMAIINLFMYNYFEKTCHQYADNTIYVKKAPENVFIFNFDLDNNTKMKLFEYGIEAAEEFIKNKFDNK
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Uncharacterized protein L446.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GCH1_CLOK1
Sequence: MDENKIKDAVRMIIEAIGENPEREGLAETPDRIARMYTEIFSGLKEKPEEHLKKVFTVNNDDIVLEKDIQFYSMCEHHFMPFYGKTHVAYIPNGKVVGLSKLARTVEVFAKRLQLQERMTVQIADSIMDYLKVKGVMVVIEAEHMCMTMRGIKKPGSKTVTVATRGIFKNKIEFRNQVYEMIKMK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: TIG_FRATF
Sequence: MQVTLEKKEGIHCSLLIEVPANEIDSVVSKEINRTAKTIKMDGFRPGKVPAGMVKKKYGEQIRMEVISDLIPQKYSKAIQDEKLAVAGIEVELKENKEGQPLKFVANLELFPEFEVTGFEKIEVQKPVVELTDKEVKQMIENLRKQFATFSEVYKVVEKDDKVTIDFVGKKDGEAFEGGTANDIDVIIGSGQMIPGFEDGIIGMKKGEQKTITVTFPQDYQNKDLAGAETTFDITVKKIQQAELPEVNDEFVKKFGVKGGVDTFENEIKENMQRELKFILQRKVKDQVFKGLREIAKFETPKSLIKREIDAAKQNLLKQMGGAKGFDVNQLPDNLFEANAKQKVETSLILDSIMNSQEFKAEEAEVESLLDELVQAYEEPEKTKEQIKKNDKEIANLKALVIENKLTDWVLEQAKVTEKTEDFFEVIKENMQAQQAGF
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: S2529_HUMAN
Sequence: MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQPSSL
What is the function of this protein?
Mitochondrial transporter of arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine (PubMed:19287344, PubMed:24652292).  Does not transport carnitine nor acylcarnitines (PubMed:24652292).  Functions by both counter-exchange and uniport mechanisms (PubMed:24652292).  Plays a physiolocical role in the import of basic amino acids into mitochondria for mitochondrial protein synthesis and amino acid degradation (PubMed:19287344, PubMed:24652292).
What are the official names of this protein?
Mitochondrial basic amino acids transporter, Carnitine/acylcarnitine translocase-like, CACT-like, Mitochondrial carnitine/acylcarnitine carrier protein CACL, Mitochondrial ornithine transporter 3, Solute carrier family 25 member 29.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: Y3016_METHJ
Sequence: MAEDELAEIRRRKMAEMQQHAAMQQQDMERQQQYEAQMQMALMQILEPEARERLNTIKLTKPDFARAVEQQLVMLAQSGRIKNKISDDQLKVILQQVTPAKREFNIRRKG
What are the official names of this protein?
DNA-binding protein Mhun_3016.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: PLSY1_LACAC
Sequence: MARIYATLIGYVFGNFLTAMIVGKLFLKINPTEYGSHNPGTANMGAVFGKKWGILTCLGDLLKSLIALFIVYFVFPGHINIAYAGLGLILGHCFPIWNHFKGGKGVAVSAQVAVFYDWRAGLATLLIALILTAIMQNLTIPPLVFMLLFSVYEFWQNQEAGIVFMVITLIMVYKFWQDIIDFFTGHGKRVDILYSIKKKLGIKSE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 1, Acyl-PO4 G3P acyltransferase 1, Acyl-phosphate--glycerol-3-phosphate acyltransferase 1, G3P acyltransferase 1, GPAT 1, Lysophosphatidic acid synthase 1, LPA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPP_LACJO
Sequence: MLVPTVIEQTARGERAYDIYSRLLKDRIIMLSGEINDQMANSIIAQLLFLDAQDNTKDISLYINSPGGVITSGLAIMDTMNFIKSDVSTIAIGMAASMASILLTSGTKGKRFALPNSTVLIHQPLGGAQGQQTDIQIAANEILKSRKKLNQILHETTGQPLDKILKDTERDNYLSAEEAKDYGLIDEILVNQKKD
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1C_PROMM
Sequence: MSSGLDLELSFSQSLQGLGLSPQVAHLIWLPLPMLLVLTAAMVGVLVTVWLERKISAAVQQRIGPEYAGALGVLQPMADGLKLLVKEDVIPVRADGLLFTLGPVLVLVPVILSWLIVPFGQNLLISNVGIGIFLWISLSSIQPIGLLMSGYASNNKYSLLGGLRAAAQSISYEIPLALAVLAVVMMSNSLSTVDIVAQQNGAGLLSWNVWRQPVGFLIFWICALAECERLPFDLPEAEEELVAGYQTEYAGMKFALFYLGSYINLVLSSLLVAVLYLGGWGFPIPVEWLAGWLGQSVDAPLVQVITGSVGIVMTVLKAYLLVFLAILLRWTTPRVRIDQLLDLGWKFLLPIALGNLLITAALKLAFPVAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: ACCD_XANAC
Sequence: MSWLSKLMPSGIRTENTPAKKRSVPEGLWEKCSNCGSALYGPELEENLEVCPKCDHHMAIRARARLNSLFDPDTATTEIAAQLGPVDALKFKDQKRYGERIKASQKASGEYDALIAMRGTLKGNPLVAAAFDFAFMGGSMGSVVGERFARAAEVALEVGCPFVCFSASGGARMQEGLFSLMQMAKTSAALGRLREAGLPYISVLTHPTTGGVSASFAMLGDINIAEPHALIGFAGPRVIEQTVRETLPEGFQRSEFLLDHGTIDQICDRRQMRDRIAELTAMMMRQPHPQDADAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP1_SCHPO
Sequence: MPTYSKRKSRGSLEVSEKTNQPKFIKRSQSSETITSGETASELMQDEKEQSNGAVGSIEDEELQRLRENQASVEALSKKPESIDRELGVEALEIDNVVKSDEEKEDPNGASSKTVKARPLPAGSVHRVTTHMAPIPARSIGSHDTTTQRLIVVLDQACLEIYKVGKAKDAKYQLLNCDDHQGILKKLNRNIAQARPDITHQCLLTLLDSPLNKAGRLQVYIHTAKKVLIEVNPSVRIPRTFKRFSGLMVQLLHKLSIRSVNGNEKLLKVIKNPVTDYLPPNCRKATLSFDAPTVPPRKYLETLQPNQSVCIAIGAMAHGPDDFSDGWVDEKISISDYPLSASIACSKFLHSMEDFLGIV
What is the function of this protein?
S-adenosyl-L-methionine-dependent pseudouridine N(1)-methyltransferase that methylates the pseudouridine corresponding to position 1189 (Psi1189) in S. cerevisiae 18S rRNA.  Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.  Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre-ribosomes (By similarity).  Essential for cell growth.  It also has a key role in promoting the mating function (PubMed:9133664).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase mra1, 18S rRNA (pseudouridine-N1)-methyltransferase, Multicopy suppressor of ras1-deficiency protein.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: BACA_RHIME
Sequence: MFQSFFPKPKLFFISSAVWSLLAVLAWYAGGRDIGAYLGLPPLPPGQEPVIGVSVFWSTPFLWFYIYYAVVAGLFAAFWFAYSPHRWQYWSVLGTALIIFNTYFSVQVSVAINAWYGPFYDLIQQALARTAPVTAGQLYSGMIGFSGIAFVAVTVGVLNLFFVSHYIFRWRTAMNEFYVAHWPRLRHVEGASQRVQEDTMRFSSTVERLGVGLVSSIMTLIAFLPVLFKFSEQVNVLPIVGEIPHALVWAAVFWSVFGTVFLAAVGIKLPGLEFRNQRVEAAYRKELVYGEDHEDRADPITLAQLFDNVRRNYFRLYFHYMYFNIARIFYLQADNLFGTFVLVPAIVAGKLTLGVMNQVLNVFGQVRESFQYLVNSWTTIVELLSIYKRLKAFESVLVDEPLPEIDRQFIDAGGKEELAL
What is the function of this protein?
Functions in the transport of molecules, possibly peptides, across the inner membrane.  Is essential for bacteroid development.
What are the official names of this protein?
Bacteroid development protein BacA.
What is the protein family that this protein belongs to?
Belongs to the peptide uptake permease (PUP) (TC 9.A.18) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEFI_BOMPA
Sequence: VTCDLLSIKGVAEHSACAANCLSMGKAGGRCENGICLCRKTTFKELWDKRF
What is the function of this protein?
Antibacterial peptide against Gram-positive and Gram-negative bacteria and fungi.
What are the official names of this protein?
Defensin.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS19_BURA4
Sequence: MARSVKKGPFCDAHLLKKVEAAAASRDKKPIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISENMVGHKLGEFALTRTFKGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SEPS_METLZ
Sequence: MKFDIEEFKERRKTDFEGAWHAGPSVITPPESSKIYPRYAYRRAKVHPIFDTIARLRAAYMSMGFDEAMVPVFIDEQDVYRQFGPEAAAVLDRVYYVGGLPRPNVGISRERLDAIAEIIEKPLAEGTEEKLMKCLHAYKKGKFDGDDLTHEMSVALGVDDGVVVHILDTVFPEFKELAPESSRTTLRSHMTSGWFISLAQMWDKKPMPIRMFSVDRCFRREQEEDATHLRTYHSASCIVAGEDVTVEEGKAVAEGLLSAFGFTEFRFQPDEKRSKYYMPETQTEVYGKHPVHGWVEVATFGIYSPAALAEYGVGVPVMNLGMGVERLAMVLTQAEDVRKLSFAQLYPPVYSDTDLTKGIGLREEPQTAEGRRAVRAVMETAAAHAAERSPCSFPAWKGELYGHQVEIVVEEPEENTSLLGPAALNEVYVRKGAVLGVPDTEKFADVKAEGVPVGISFLYSTANLALARIEEAARVGEGTSIQVKMSKHPSDVNLKIEEYVMRYITDNKKKLDLRGPVFMTITSKIL
What is the function of this protein?
Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
What are the official names of this protein?
O-phosphoserine--tRNA(Cys) ligase, O-phosphoserine--tRNA ligase, Non-canonical O-phosphoseryl-tRNA(Cys) synthetase, O-phosphoseryl-tRNA(Cys) synthetase, SepRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
Protein: FBX10_HUMAN
Sequence: MEAGGLPLELWRMILAYLHLPDLGRCSLVCRAWYELILSLDSTRWRQLCLGCTECRHPNWPNQPDVEPESWREAFKQHYLASKTWTKNALDLESSICFSLFRRRRERRTLSVGPGREFDSLGSALAMASLYDRIVLFPGVYEEQGEIILKVPVEIVGQGKLGEVALLASIDQHCSTTRLCNLVFTPAWFSPIMYKTTSGHVQFDNCNFENGHIQVHGPGTCQVKFCTFKNTHIFLHNVPLCVLENCEFVGSENNSVTVEGHPSADKNWAYKYLLGLIKSSPTFLPTEDSDFLMSLDLESRDQAWSPKTCDIVIEGSQSPTSPASSSPKPGSKAGSQEAEVGSDGERVAQTPDSSDGGLSPSGEDEDEDQLMYRLSYQVQGPRPVLGGSFLGPPLPGASIQLPSCLVLNSLQQELQKDKEAMALANSVQGCLIRKCLFRDGKGGVFVCSHGRAKMEGNIFRNLTYAVRCIHNSKIIMLRNDIYRCRASGIFLRLEGGGLIAGNNIYHNAEAGVDIRKKSNPLILCNQIHHGLRSGIVVLGNGKGIIRNNQIFSNKEAGIYILYHGNPVVSGNHIFKGRAAGIAVNENGKGLITENVIRENQWGGVDIRRGGIPVLRSNLICFGYSDGVVVGDEGKGLIEGNTIYANKGCGVWMMSSSLPHVTSNHVSYNGLYGVAVFSQKDGSSELPRGHRAQENFSEDGDAILWETELEKEDDPLRRPITIALVESNSINHNGASGLYVQSSEALHVITNVIHANGDRGITVAQSSQPTRVANNSISCNRQSGVKVEAQCKVELRGNGIYDNRGHGIITKGDSTIVIENDIIGNRGSGLQLLPRSDTKVIKNRIHSFRAYGIAVRGRAKALVQENIIFQGKTSKTIFQQISNNRECIMQNNKFLVFKKKSDTWRLVNPPARPHLENSLRRPSAAHNGQKVTAMATRITARVEGGYHSNRSVFCTIL
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Mediates the ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2.  Targets also the receptor for advanced glycation end products RAGE for ubiquitination and subsequent lysosomal degradation (PubMed:28515150).  Directly controls HGAL/GCSAM ubiquitination and degradation and thereby decreases BCR signaling (PubMed:31570756).
What are the official names of this protein?
F-box only protein 10.