Protein: ANKHM_DROME
Sequence: MNNDAKNHESDDLNVRSTAYFNQQTTTNQPKAPATSKNNTGSGSGSNNNNNNTNQNPNRQLNHNLPRIAAARQSIAAALLKNSGRKILTAKNEPLTTTESSGVLTNTPLPSNSRLKVNNNNNTNNTAKMSGTSSSQSSATPTPPTASSSTTTTTTTNISTGGGGSGSSGGGGGSTTVIANPASVTNTGAGSAAKFRAAVASAPSPALPATNAPANATAAAAIAAIATAPAPSSSSSSSSSSKKTRAAVAALKRQVALQQQQPVTGNAPNMTSKDSAHLKFATTTLLMGAAAAAADSNAGAALGGSGAGGSGSSSSVGAVGGARMALNPAVDMANAAVLLKQKLKDAAAAASASASNRSATSSMSSTASSLSSSAGIVNAISSALQNIITPDTDTDTEFYPQPVTTDLSESEEESVSEDDIPESDPDSCPHEGEVREDEDETEEESEDSDESEGEEEEEDEEEIDVLQDNDADDEEIDDEDEEEDAPEVSSFLLDANNKRSSNISALLEAAANEKAPVLRHATHAIDETKQALTKMRCASSPRDKNSGFSRSLVAACTDNDVNTVKRLLCKGNVNLNDAAASTDDGESLLSMACSAGYYELAQVLLAMSAAQVEDKGQKDSTPLMEAASAGHLDIVKLLLNHNADVNAHCATGNTPLMFACAGGQVDVVKVLLKHGANVEEQNENGHTPLMEAASAGHVEVAKVLLEHGAGINTHSNEFKESALTLACYKGHLDMVRFLLQAGADQEHKTDEMHTALMEASMDGHVEVARLLLDSGAQVNMPTDSFESPLTLAACGGHVELATLLIERGANIEEVNDEGYTPLMEAAREGHEEMVALLLSKGANINATTEETQETALTLACCGGFMEVAAFLIKEGANLELGASTPLMEASQEGHTDLVSFLLKKKANVHAETQTGDTALTHACENGHTDAAGVLLSYGAELEHESEGGRTPLMKACRAGHLCTVKFLIQKGANVNKQTTSNDHTALSLACAGGHQSVVELLLKNNADPFHKLKDNSTMLIEASKGGHTRVVELLFRYPNISPTENAASANVTQAAPTSNQPGPNQMRQKIMKQQLQHQLQQLNAPPGLHELSEAARASNQQHFHQQQFSSAGNGSSNIVAMGTGDFLDAGELQLTATAGMSAGAGTSTTGSETGMEEYGEVGGIDLTTLGAQQQEGLIAKSRLFHLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPPAAGQHQLVPCKHFDLDMEHINSLQPPQKAPPAPPVLFHTVCQQPVMQQQQQQLQPGQLKLKAMLPNRNRALKTAEVVEFIDCPVDQQQPGEQVRTQPLGEDGKTPQFACAGEDPRLQRRRGFMPELKKGELPPESSSSDPNELALKGADNNQPVPTALDNSACAQIPARNSGGAITHSSEVLQSTAISDRPKVKATNKNNRKQAAAAAAAAAAAAAAAAAAAQHAQQVLPNPMVSIYNNLHLQHLQHPHLQFQQQLQLHHQRVAGLDNAAAAAAAAASSANMAYSISPASPLPSPTGSGNYVDQQLQQQSMDVALQRKTAMDDFRGMLETAVNGPRGRKDLALNTPQLNFFKDGWHMVGVHNFFGDQPKSPTETPPEMEETTMSSPTEADRLGSEPRAEMKNLATLCSAAAAAAAVAAVNKDQVEISSDLESECEDDAEGGAGADCEENTLPPEPIELAAALREDGIIVEEEEDDEEEDDDDEEQDTNSGEVDKLNYDDEDAEVDNDGEVDYIDEDEGGGEGEEEEDDADDDEFFLDEPDSDQGTGNNNNNSKSGASSLPLKQRKMATRLENLILNSQTVCDFPPELSNSELVHVLPQISNLKAAANSNAALNSVLQQQLAAASAAAAHAKASVVHQKQQHGEGDQQCEDDGSASASELYSGLEHFANDGEMEDIFQELASSLNYPELAEFSLNQMCKGRFAGNWAQSSGKWTGQEQLVGVVRSPGLINPGDVPQDAQRQANLVLLDYPMQQNIQLEQRLLDAEEMHLQQHQQTPLSLLPFTDEQQQQLHHQALSNASDFQQHQQLALENDPELKQQLQQNSNARIIKAVAAQHQQQPPTNFVYNVESGDKNAPPVQLLFQLPPHMAQHQAQQQQGVGEPLTEQQQQQLHAEQAHLFQHRTGGQRPPTQSELEQVAQELLLQRSGQVPAGAPVVGVQAIPLKQKHFNLHPPPCPPTCVQHQVATQTHPASVVVPQPAVGYTQFALQASQQQQMQQNELSIWPMATPTPAPSSGVSSTKSMPGGIAKKAIDKQSRKERRCVVRQTPAGIQENTKLHLQPQVATAQQQFLVQNQLAVATTVSLDKTIEIDSETESNHDTALTLACAGGHEELVELLINRGANIEHRDKKGFTPLILAATAGHDKVVDILLKHSAELEAQSERTKDTPLSLACSGGRYEVVELLLSVGANKEHRNVSDYTPLSLAASGGYVNIIKLLLSHGAEINSRTGSKLGISPLMLAAMNGHTPAVKLLLDQGSDINAQIETNRNTALTLACFQGRHEVVSLLLDRRANVEHRAKTGLTPLMEAASGGYIEVGRVLLDKGADVNAAPVPTSRDTALTIAADKGHQKFVELLLSRNASVEVKNKKGNSPLWLAAHGGHLSVVELLYDHNADIDSQDNRRVSCLMAAFRKGHTKIVKWMVQYVSQFPSDQEMIRFIGTISDKELIDKCFDCMKILRSAKEAQAVKANKNASILLEELDLERTREESRKAAAARRRERKKKKKMEKKEEKRRQQQGNGPGGDDMQGDDDDASDKDDDSDKDDEDEEAAPAAAREEGDSGIDQGSCSSGDTKGARFGGSQSAQAAEAAANSVSTNSQGKKNKKQAKNKVLISVEPTQPVITSNSVLKGVCAKKHPAVEVVKQPPATQQAAPLKRQLDVKKEEPALKKKEEKNSSSSSSSKREKENLAPKEVALPAKQQPSSSSKLQSSESASNINSSTATNTSSANTTRKEVAKPASQTASATTLNPAKRTEVDGWKEVVRKSSAQQTTAVGASGAPLPVTATSSATSVQHHPHHHLANSSSNSSSSLTTSTTTAASSVPEMTCKKVQVPVNAISRVIGRGGSNINAIRATTGAHIEVEKQGKNQSERCITIKGLTDATKQAHMLILALIKDPDVDILQMLPRINSSIKQASSGGASTPMSVGTWDNRTAAGVNAYTFSSAASTTSTSSSSSASSTTPAGASYSNAHKQHQQQPQSVKGPSGRSSTSVKSNGSSTKVSASSGSGSRSGRAGSSYLAQQQPGRSSGGGSSNGVIKSKSESSSKSLPAAQKSSTTLGKSSTVSPGAQNFAKAAAIGQSSPKKAEGGATSAVVTSAGGRSSGVVAPFGRGKPVAGQGGPAATAASNVAQLGSVSGNSNILAGPIGTFNVADVAAVNAAAAAGAAAATNSNVKPIAPIAPPSKRVGSPTQVQQQHQTQQQQQQQLPQPAPVPGPQPQQQPLQQQQQQQAPQQQPQQPNQQQQPQTSQQNLVINTNLLNDLMAASAANTTSDSFSAQLAAKLSSAYSLFSDYQQSQWGKLGDPGIGGGAGAVGDGLPQADASKAPGYNRNILSSPVGSSKASSNHSTSPPVGNVIQQQQQQQPQSSQQALNIITSGPGGPATAPARSPMVSANEGNPAVGQPSMNGTQGLGETAPAHSPGVIKPPTATVPIQRHVPMPISAPEAGAPPTFGAIGSNPASGNNSAAAQAAAAAAASAMIDRQQQNLQNLQTLQNLQRMVGASQQQQPQQQLNYPMDPTSSFIVDANNVLRLNPRVIFPQGNTKPPQPPPQGGTQSNVFGGNPGRQPPGTGARQPGGAAAQRWYGGTLEYPSYTGRDMLHLENGAGGMAGMGSPSAMSPNHDDIRKMPRPIGTERAASWKYNNFNVGGPSLNMEDALASVLPPWAHELKAQPPGLQQPPPPPQSQQQQQQPLNWLKQQPQQQQYRAYNNGPYPQQQQQHEPMNMPMDYHNMQAPPNMSQQQQQHVNLMPSYGYQHFVGAPGAVDISAHMPDKMEVWDHHDKHMPWTNYTTNWSN
What is the function of this protein?
Mediator of receptor tyrosine kinase (RTK) signaling, and may act either downstream of MAPK or transduce signaling through a parallel branch of the RTK pathway (PubMed:11782402).  Required for the development and organization of indirect flight muscle sarcomeres by regulating the formation of M line and H zone and the correct assembly of thick and thin filaments in the sarcomere (PubMed:26251439).
What are the official names of this protein?
Ankyrin repeat and KH domain-containing protein mask, Multiple ankyrin repeat single KH domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere, M line. Note=In indirect flight muscle, more strongly associated with Z lines where it colocalizes with sls isoform A (kettin).