PharMolix/UniProtQA huggingface dataset:
Protein: MTD2L_HUMAN
Sequence: MTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSAFRGFRSSGVRHEAIIISGTEMAKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY
What is the function of this protein?
Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities.
What are the official names of this protein?
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial, NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein, MTHFD2-like.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Z518B_HUMAN
Sequence: MKDIGQQLYTTHLNGGHNSLTMSPKQPDANGAPRPNRQEAQTLLYQGSEAEAAMMTIATCAKCKSVHKISLQDLQKGTGKDGMYVCFQCSLGAAPPNFHFVSNNSSATHVGNKTENFSSSVNSKFKVRNFKPGKYYCDKCRFSTKDPLQYKKHTLQHEEIKFICSHCSYISYTKGEFQRHLVKHTGIFPYQCEYCDYGAIRNDYIVKHTKRVHERAGAKRPVKAVAKLEPKRTGTSKQNPELLKASNPRTTFQNKWSDQLSGFSLHANKDKMHNIMLLPEPKEYQKDVVCIPNKMTLSEPNEVNLFENKNVEVEVLSPAKEPVQPGMPLTVVAPAELVVPANCLAQLIDVKVVNGTQQLVLKLFPLEENNCLEAGRDNGGNSERMVKEKGSNEQEKVLSAEKTKSLTVDGNVGKLVGIDSFQPSVQKQLKNVKWVRSYDFIMPNSSVHNNGKSFINSETIEDFQKKNNLYPHRTAFPSVALKGHSLASVFKNSVLRSLGAASNPFPYKAAVCFAESGRNLHSSSQQLLPFAASPATCSFSGEKGLLPVSENDLESTSKVNIPVKVVSSNRKQEDNQTEEHKAVSTVGQISSQHKSEYLHINITGEDRSQQPGDKPLELKNSERTNNTNDGPVISSVFSLSSGSENVPEGIKWNSSTSKIKSIELLRRKIAQLIESCGKPSSLASNSAHRRSVGQASKGTSKATSEGIQEINVSLTGLGHSTGTLQKPPNDGGITGNRQLTHQQIYPHFADGSNRKTKSRVARKAHVATPVLIPKGAVLRVLNSSENAHIIEATCEAPVSIPCSERQLIKPVPFCPVRQADSDLQPLRSERGPIDMSPNIETPLRPKLRKESAVCSTIHRKTGLLYGQQGSSELNKQGRLLSRSLSISRNKTKQVHLSRKKNKIQAEPSRCLKDPSIFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRCQLGIRRHHVRLTYQNAEEASQIKRQMMLKMKLKKVHKNNYQVVDSLPDDSSQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK
What is the function of this protein?
Through its association with the EHMT1-EHMT2/G9A and PRC2/EED-EZH2 histone methyltransferase complexes may function in gene silencing, regulating repressive post-translational methylation of histone tails at promoters of target genes.
What are the official names of this protein?
Zinc finger protein 518B.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CQSA_VIBCH
Sequence: MNKPQLPDFIQNKIDHYIENYFDINKNGKHLVLGKQASPDDIILQSNDYLALANHPLIKARLAKSLLEEQQSLFMSASFLQNDYDKPMIEKRLAKFTGFDECLLSQSGWNANVGLLQTICQPNTNVYIDFFAHMSLWEGARYANAQAHPFMHNNCDHLRMLIQRHGPGIIVVDSIYSTLGTIAPLAELVNISKEFGCALLVDESHSLGTHGPNGAGLLAELGLTREVHFMTASLAKTFAYRAGAIWCNNEVNRCVPFISYPAIFSSTLLPYEAAGLETTLEIIESADNRRQHLDRMARKLRIGLSQLGLTIRSESQIIGLETGDERNTEKVRDYLESNGVFGSVFCRPATSKNKNIIRLSLNSDVNDEQIAKIIEVCSDAVNYGDFYFR
What is the function of this protein?
Required for the synthesis of the quorum-sensing autoinducer CAI-1 ((S)-3-hydroxytridecan-4-one) which probably functions as an intragenus signal.
What are the official names of this protein?
CAI-1 autoinducer synthase, Cholerae quorum-sensing autoinducer.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: CH602_MYXXD
Sequence: MAKDILFDVRAREAILRGVNILADAVKVTLGPKGRNVVIEKSFGSPTITKDGVTVAKEIELENKFENMGAQMVKEVASKTSDVAGDGTTTATVLAQAIFREGAKLVAAGHNPMDIKRGIDKAVGAIVAELKKLAKPTKDKKEIAQVGTISANGDETIGTIIADAMEKVGKEGVITVEEAKGLETTLDVVEGMQFDRGYLSPYFVTDPERMEAALNDALILINEKKISSMKDLLPILEQVARAGKPLLIIAEDIEGEALATLVVNKIRGVLNVCAVKAPGFGDRRKAMLEDIATLTGGRMIAEDLGIKLDTITLQDLGRAKRITVDKDNTTIVDGAGGQQEIEARVKQIRAQIEETSSDYDREKLQERLAKLVGGVAVINVGAATETEMKEKKARVEDALNATRAAVEEGVVPGGGVAYIRCLKALDGLQLSGGEKFGVDIIRRAVEEPLRQIVGNGGLEGSVVVNKVKESSGPFGFNAATGTYEDLLAAGVIDPAKVSRTALQNAASVSSLMLTTEAMVAERPKEEKDLPAGGGMGGMGGMGGMGGMGM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMA1_HUMAN
Sequence: MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN
What is the function of this protein?
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
What are the official names of this protein?
Chymase, Alpha-chymase, Mast cell protease I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Mast cell granules.
Protein: MNME_BACSU
Sequence: MDTIAAISTPMGEGAIAIVRLSGPEAIQIADKIYKGPKGKTLSSVESHTIHYGHIVDRPSDRVVEEVMVSVLKAPRTFTREDVIEINCHGGIVTVNQVLQLALREGARLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMNVAMNQMEGRLSALVRRLRSEILETLAHVEVNIDYPEYDDVEEMTHQILVEKATAVKKEIETLLRTSEQGKILREGLSTVIIGRPNVGKSSLLNSLVHEAKAIVTDIPGTTRDVIEEYVNVRGVPLRLVDTAGIRETEDIVERIGVERSRQVLKEADLILLVLNYSEELSEEDVKLFEAVEGMDVIVILNKTDLEPKIDTERVRELANGRPVVTTSLLKEEGINDLEEAIQSLFYTGAIESGDLTYVSNTRHITILQQAKRAIEDALSGIEQDVPIDMVQIDLTRCWELLGEIIGDSVHESLIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAR_ECOHS
Sequence: MAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFNASAGQPHWRLGSMGMAQARQVIGQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRHLNSQKD
What is the function of this protein?
Activates expression of the rhaSR operon in response to L-rhamnose.
What are the official names of this protein?
HTH-type transcriptional activator RhaR, L-rhamnose operon transcriptional activator RhaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRRS7_ARATH
Sequence: MARIILTAPLFYFFFSLLSHQTMSQPQHMHTFCSVDSFTQTSSYETNRNILLTTLSLTSSLVHYLNATIGLSPDTVYGMFLCRGDINTTSCSDCVQTAAIEIATNCTLNKRAFIYYDECMVRYSNVSFFSEFESKPVIVRYSLRSAPNSNRFNQTLSNKLDQLIPNVSPSTLIPYFVEDQERVTQLEGSYDLVSMIQCSPDLDPSNCTICLRFAYATVSTCCGVPSSALIFTPKCILRYRTFVLPSPAPSPSSLPPISPTSSPPLSLPPQLPPPLSQPPPPLST
What are the official names of this protein?
Putative cysteine-rich repeat secretory protein 7.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: KCC2B_RAT
Sequence: MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSSAITSPKGSLPPAALEPQTTVIHNPVDGIKESSDSTNTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRPDGKWQNVHFHCSGAPVAPLQ
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle (PubMed:12873385, PubMed:15312654).  In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.  This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.  In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling.  Also regulates the migration of developing neurons.  Participates in the modulation of skeletal muscle function in response to exercise (PubMed:17272343).  In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.  In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (PubMed:11972023).  Phosphorylates reticulophagy regulator RETREG1 at 'Ser-134' under endoplasmic reticulum stress conditions which enhances RETREG1 oligomerization and its membrane scission and reticulophagy activity (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type II subunit beta, CaM kinase II subunit beta, CaMK-II subunit beta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Synapse. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with the cortical actin cytoskeleton by binding to F-actin in hippocampal cells.
Protein: UGDH_RAT
Sequence: MVEIKKICCIGAGYVGGPTCSVIARMCPEIRVTVVDVNEARINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIREADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPKEKILTTNTWSSELSKLAANAFLAQRISSINSISALCESTGADVEEVATAIGMDQRIGNKFLKASVGFGGGCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSADDQVSRLVTISKDPYEACDGAHALVICTEWDMFKELDYERIHKRMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYTPGEIPKFSLQDPPNKKPKV
What is the function of this protein?
Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans (By similarity).  Required for the biosynthesis of chondroitin sulfate and heparan sulfate.  Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity).  Required for proper brain and neuronal development (By similarity).
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: SYE2_LEVBA
Sequence: MAKNSIRVRYAPSPTGHLHIGNARTAIFNYLFARHNKGKFIIRIEDTDTKRNIEDGERSQLENLKWLGLDWDEGPDVGGDYGPYRQSERRDIYTPLIQQLLDEGKAYESYRTEEELQADREAQKARKEMPHYEYEYAGMSEEEKQAAIDEAKAKGLKPVIRFRVPKDEVFAWDDMVKGHVSFNSDTIGGDFVIAKRDGMPTYNFAVVVDDHKMAISHVFRGDDHVANTPKQLMIYQAFGWEAPKFGHMSLIISKDTGKKLSKRDESVLQFIEQYRSLGYLPEAMFNFILLLGWSPVGEEEIFNKKQFIKMYDETRLSSSPATFDSDKLEWLNNRYVKDADDSTIMDLALKQLIKAGNMPANPDAKTIEWARQLINLYKRQMSYMAQINDMASVFFEEPEQVSGEAFDEINNDTAPVVLKEFAAQIEALDLFDSVEIFKVIKSVQAKTGIKGRQLWMPIRIAVTHEMHGPELPESIELVGRETALEHIHQTLAQLKG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 14332_ENTH1
Sequence: MTSREDLVYLSKLAEQSERYEEMVQYMKQVAEMGTELSVEERNLISVAYKNVVGSRRASWRIISSLEQKEQAKGNTQRVELIKTYRAKIEQELSQKCDDVLKIITEFLLKNSTSIESKVFFKKMEGDYYRYYAEFTVDEKRKEVADKSLAAYQEATDTAASLVPTHPIRLGLALNFSVFYYEIMNDADKACQLAKEAFDEAIQKLDEVPEESYKDSTLIMQLLRDNLTLWTSDMGDDE
What is the function of this protein?
Probable adapter protein.
What are the official names of this protein?
14-3-3 protein 2, 14-3-3-2, EhP2.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: FMT_COLP3
Sequence: MVTPLNIIFAGTPEFAAQHLAALINSEHNIVAVYCPPDKPAGRGKKLTACATKLLAIEHDIIVEQPINFKNEEDQQQLAKYNADIMVVVAYGLLLPEVILNSPRLGCINVHGSILPKWRGAAPIQRSLEAGDKKTGVTIMQMDKGLDTGDMILSAECEIENTDTSASLYEKLANLGPTALVNTLTIMAEPDYQASNHNIAQDDELATYAKKLDKTEAELNWQFSADELHRKIRAYIPWPVAQFTFTESEGKQHRLRIWQASVQEYRGNADPGTIIKADKEGIEVATTSGSLRLEVIQLPGKKALAVKDILNGRSDWFVVGSTINKLG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CENPV_MOUSE
Sequence: MRRTRSAVATGPREQRRSGATGGLSGGESRAQRSRSRTRAGAGGGGGAVGPQPSAKPRPKPPPRAQEAAAEEPPPAVTPAASVSALDLGEQRERWETFQKRQRLSFEGAAKLLLDTFEYQGLVKHTGGCHCGAVRFEVWASADLHIFDCNCSICKKKQNRHFIVPASRFKLLKGAESITTYTFNTHKAQHTFCKRCGVQSFYTPRSNPGGFGIAPHCLDEGTVRSVVTEEFNGSDWERAMKEHKTIKNMSKE
What is the function of this protein?
Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis.
What are the official names of this protein?
Centromere protein V, CENP-V, Proline-rich protein 6.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Enriched at the nuclear periphery and around the nucleolus. In mitotic cells, localizes to kinetochores from prometaphase to metaphase. At anaphase onset, transfers to the spindle midzone and then to the mid-body in telophase and cytokinesis.
Protein: PUR4_PSE14
Sequence: MLILRGAPALSAFRHSKLLEQLKQKVSAVSGLYAEFAHFADVNDVLTSEEQQVLDRLLKYGPSVPVQEPSGRLFLVLPRFGTISPWSSKASDIARNCGLTKIQRIERGIAFYVEGQFSEAQAQAIADSLHDRMTQLVLGDHEQAASLFSHAQPKPLTAVDILGGGRAALEKANVELGLALAEDEIDYLITSFNGLGRNPHDIELMMFAQANSEHCRHKIFNASWDIDGQSQEKSLFGMIKNTYQMHSEGVLSAYKDNASVIVGNVAGRFFPDPETRQYGAVQEPVHILMKVETHNHPTAIAPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFVQPWEVPYGKPERIVTALDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSITTPHGDEVRGYHKPIMLAGGMGNIREDHVQKGEITVGSKLIVLGGPAMLIGLGGGAASSMATGTSSADLDFASVQRENPEMERRCQEVIDRCWQLGDRNPISFIHDVGAGGLSNAFPELVNDGDRGGRFELRNVPNDEPGMAPLEIWSNESQERYVLAVGVEDFDRFKAICERERCPFAVVGEATAEPQLTVTDSHFGNSPVDMPLEVLLGKVPRMHRSVEREAEIGDDFDPSTLDIEESVQRVLRHPAVASKSFLITIGDRSITGLVARDQMVGPWQVPVADCAVTATSFDVNTGEAMAMGERTPLALLDAPASGRMAIGETLTNIAASCIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKDSMSMKTRWSDEGTEKSVTSPLSLIVTGFAPVVDIRQTLTPELRMDKGITDLILIDLGRGQNRMGASILAQTHGKLGRVAPDVDDAEDLKAFFAVIQGLNSDGHILSYHDRSDGGLLVSTLEMAFAGHCGLNLHLDGVADNVSELSAILFNEELGAVIQVRQDATPLVLAQFSAAGLEDCVAVIGQPINNDEVSISFHGEPVFSGQRRLLQRQWAETSYQIQRLRDNAECADQEFDALLEEDNPGLTVKLGFDVNEDIAAPYIKTGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDVHMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERADSFTLGVCNGCQMLSNLHELIPGSEFWPHFVRNRSEQFEARVAMVQVQESASIFLQGMAGSRMPIAIAHGEGHAEFRNDDALLEADVSGTVALRFVDNHGKVTETYPANPNGSPRGIGGMTTLDGRVTIMMPHPERVFRAVQNSWRPEDWNEDAAWMRMFRNARAWVN
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_CITBB
Sequence: MGETVRFGISMDDQLLESFDRLIEQKGYANRSEAIRDLIRAAQVELDWEEGEKEGVGTVTLVYNHHVRDLSDKLTEHQHAHHDQIISALHVHLDAHNCLEVLVVRGKARDVRRIADELIGVKGVKHGKLVMTTTGEGLH
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: HTPX_VIBPA
Sequence: MKRIMLFLATNLAVVLVLSVVLNIVYATTGMQPGSLSGLLVMAAVFGFGGALISLMMSKGMALRSVGGMVIESPRNETEHWLLETVGRQAQQAGIGMPTVAIYDSADINAFATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQGVVNTFVIFLSRFIANIVASNDDEEGQGTNMMVYFGVSMVLELVFGFLASFITMWYSRHREFHADAGAARLVGKEKMIAALERLKMSQESKLDGTMMAFGINGKQSLTELLMSHPPLDKRIAALRNQ
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEND_PHOLL
Sequence: MSNSAFNRRWAELLLEALTRHGLRHVCIAPGSRSTPLTIAAAANNKLICHTHFDERGLGHLALGLSKASREPVAVIVTSGTAVANLYPSLIEASLTGERMVFLTADRPPELMDCGANQAIRQNGIFASHPCQTISLPRPTVDIPASWLASVIDHSMANLQHGAVHINCPFAEPLYGNEEPAYDEWQQQLGDWWKSKTPWLSQPVAKVVAEVPDWDCWQQKKGVVLAGRMSAEEGVNVAKWAKALSWPLIGNALSQTGQPLPCADLWLDNPHVQEILAQAQLVVQFGSSLIGKCLLQWQAKCQPQEFWIIDPIPGRLDPANHRGKKLTCHIADWLLAHPAQPCIPWAQSCTLWAEELIVWSEKAVNCVRTELAGKFGEATVAYRLRELLPERGQLFVGNSLIIRLIDTLGQLPAGYPVYSNRGASGIDGLISTAAGVQRATAKPTLAVIGDLSALYDLNSLALLRHPSAPMVLIVVNNNGGQIFSLLPTQEEARQRFYCMPQYVNFDHAAAMFGLKYASPQNWMELQQSIKQAWQQNETTLIELKVPDREGAECLQQLLKQVAML
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: TRPB2_PYRFU
Sequence: MKVVLPDGRIPRRWYNILPDLPEPLAPPLDPETNEPVDPKKLERIFAKELVKQEMSTKRYIKIPEEVRKMYSKIGRPTPLFRATNLEKYLNTPARIYFKFEGATVTGSHKINTALAQAYYAKKEGIERLVTETGAGQWGTALSLAGALMGIKVRVYMARASYEQKPYRKVLMRIYGAEVFPSPSENTEIGKRFLSENPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGLEAKQQMEEFEEPDVIIGCVGGGSNFAGLAYPFVKEVLDGDNEYEFIAVEPKAAPSMTRGVYTYDFGDSGELTPKLKMHTLGHRYHVPPIHAGGLRYHGVAPTLSVLVNNGIVKPIAYHQTEVFEAAALFAKLEGIVPAPESAHAIKATIDKAIEAKREGKEIVILFNLSGHGLLDLHGYEEYLEGRLQDYEPKDLPISNPLNPKP
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 2.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PPB_BOMMO
Sequence: MSTWWLVVVAAAAAAGLVRAEDRYHPERLAAGEASAATRSAAESEASFWVREAQEAIERREREGAGAKQAAGHAKNVVMFLGDGMSVPTLAAARTLLGQRRGQTGEEASLHFEQFPTLGLAKTYCVNAQVPDSSCTATAYLCGVKANQGTLGVTAAVPRHDCEASTDVTKRVQSIAEWALADGRDVGIVTTTRITHASPAGTFAKVANRNWENDNDVKQEGHDVNRCPDIAHQLIKMAPGNKFKVIFGGGRREFLPTTQVDEEGTRGLRTDGRNLIEEWQNDKESQKVSYKYLWNRQELLKLGSSPPDYLLGLFEGSHLQYHLEGDESTEPTLAELTDVAIRVLSRNERGFFLFVEGGRIDHAHHDNYAHLALDETIEMDRAVKVATDALKEDESLVVVTADHTHVMSFNGYSPRGTDVLGTVRSLDSNRMPFMVLSYTNGPGARIQQNGVRPDVTTDANFGALRWRTHTDVPLDSETHGGDDVTVFAWGVHHWMFSGLYEQTHVPHRMAWAACMGPGRHVCVSAATVPTAALLSLLLAAFITLRHQCFL
What are the official names of this protein?
Membrane-bound alkaline phosphatase, M-ALP.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: LDOX_MALDO
Sequence: MVSSDSVNSRVETLAGSGISTIPKEYIRPKDELVNIGDIFEQEKNNEGPQVPTIDLKEIESDNEKVRAKCREKLKKAAVDWGVMHLVNHGISDELMDKVRKAGKAFFDLPIEQKEKYANDQASGKIQGYGSKLANNASGQLEWEDYFFHCVYPEDKRDLSIWPQTPADYIEATAEYAKQLRELATKVLKVLSLGLGLDEGRLEKEVGGLEELLLQMKINYYPKCPQPELALGVEAHTDVSALTFILHNMVPGLQLFYEGKWVTAKCVPNSIVMHIGDTLEILSNGKYKSILHRGMVNKEKVRISWAVFCEPPKEKIILKPLPETVSEDEPAMFPPRTFAEHIQHKLFRKSQEALLPK
What is the function of this protein?
Oxidation of leucoanthocyanidins into anthocyanidins.
What are the official names of this protein?
Leucoanthocyanidin dioxygenase, LDOX, Leucocyanidin oxygenase, Anthocyanidin synthase, Leucoanthocyanidin hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: HPNN_RHOPT
Sequence: MLKSAIVSIVRASTRFAAFTVLIGVFLAVAAGFYTYQHFGINTDINHLISSDLDWRKRDIAFEKAFDQERLILAVVEAPTPEFANAAAAKLTAELSKNNINFDSVKRLGGGPFFDRSGLLFLPKDEVAKATGQFQQAVPLIEIMAGDPSIRGLTAALETGLVGLKRGELTLDATAKPFNTVAATVEDVLGKQQAFFSWRGLVNPEPLTDGDKRAFIEVKPILDFKALEPGKAATDAIRQAAVDLKIEQDFGARVRLTGPVPIANEEFATVKDGAVVNGIGTVVVVLLILWMALHSSKIIFAVAANLVIGLSITTAVGLMLVDSLNLLSIAFAVLFVGLGVDFGIQFSVRYRSERHKTGDLEKALVQAAEYSAVPLSLAAMSTTAGFLSFLPTSYKGISELGEIAGAGMAIAFFTSITVLPALLKLLNPAGEKEPLGYAFLAPVDHFLEKHRIAIIVGTIGVALAGLPLLYFMHFDFNPINLRSPKVESIATFLDLRKDPNTGANAVNVMAPNEQAAREIEAKLAKLPQVSRTISLDTFVPPDQPEKLKLIQAGAKVLEPALNPEQIDPPPSDQDNIASLKSSAEALRRAAGEATGPGADASRRLATALTKLAGADQAMREKAQDVFVRPLLLDFELLRNMLKAQPVTLDNLPADIVSSWKTKDGQIRVEVLPSGDPNDNDTLRKFAAAVLQAEPLATGGPVSILKSGDTIVASFIQAGLWALLSISILLWITLRRISDVALTLVPLLVAGAVTLEICVLIDLPLNFANIVALPLLLGVGVAFKIYYVTAWRSGRTNLLQSALTRAIFFSALTTATAFGSLWLSSHPGTASMGKLLALSLLTTLGAVLLFQPALMGKPRHIDESGDTDL
What is the function of this protein?
Essential for hopanoid transport from the cytoplasmic to the outer membrane (PubMed:21873238).  Required for the C(35) hopanoid, bacteriohopanetetrol, to remain localized to the mother cell type (PubMed:21873238).
What are the official names of this protein?
Hopanoid transporter HpnN.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
Protein: HLD_STAA8
Sequence: MAQDIISTIGDLVKWIIDTVNKFTKK
What is the function of this protein?
Lyses erythrocytes and many other mammalian cells.
What are the official names of this protein?
Delta-hemolysin, Delta-lysin, Delta-toxin.
What is the protein family that this protein belongs to?
Belongs to the delta-lysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Note=In infected cells, it is found in the membrane.