PharMolix/UniProtQA huggingface dataset:
Protein: FOX1_CAEEL
Sequence: MAELIEEVSTATHASLNACDPIVVNSEALPMQALYQLSATGAQQQNQQIPIGLSNSLLYQQLAAHQQIAAQQHQQQLAVSAAHQTQNNIMLATSAPSLINHMENSTDGKVKDDPNSDYDLQLSIQQQLAAAAQAAQMGQTQIGPQIVGQQGQPVVATTAGSTNGSAAVTQPDPSTSSGPDGPKRLHVSNIPFRFRDPDLKTMFEKFGVVSDVEIIFNERGSKGFGFVTMERPQDAERARQELHGSMIEGRKIEVNCATARVHSKKVKPTGGILDQMNPLMAQSALAAQAQMNRALLLRSPLVAQSLLGRGAALIPGMQQPAFQLQAALAGNPLAQLQGQPLLFNAAALQTNALQQSAFGMDPAAVQAALLANEQARFQLAAAAAQGRIPSSGNASAFGEQYLSNALATASLPSYQMNPALRTLNRFTPY
What is the function of this protein?
RNA-binding protein that regulates tissue-specific alternative splicing events by binding to 5'-UGCAUG-3' and 5'-GCACG-3' elements (PubMed:17060915, PubMed:17923701, PubMed:23468662, PubMed:33372658).  Also binds to poly(A), poly(G), poly(C), or poly(U) stretches of RNA (PubMed:9927456).  Plays a role in the sex determination pathway and X chromosome dosage compensation, and together with sex-1 is involved in making the distinction between one and two X-chromosomes (PubMed:7821230, PubMed:21471153, PubMed:23666922, PubMed:9217163, PubMed:9927456, PubMed:16139225, PubMed:17720939, PubMed:33372658).  Binds to 5'-GCAUG-3' and 5'-GCACG-3' elements in intron 6 of the pre-mRNA of the sex-determining factor xol-1 to promote its alternative splicing and together with sex-1 negatively regulates the expression of xol-1 to promote hermaphrodite development (PubMed:9217163, PubMed:33372658).  Negatively regulates the expression of the active isoform of xol-1 (isoform b) by promoting intron 6 retention and the deletion of exon 7 coding sequences in hermaphrodite embryos (PubMed:33372658).  Furthermore, binding to the pre-mRNA of xol-1 can also direct the use of an alternative 3' splice site enabling the xol-1 transcript to be trans-spliced to unrelated genes on chromosome 2, which also leads to xol-1 exon 7 deletion (PubMed:33372658).  Does not seem to regulate the retention of introns 1 to 5 of xol-1 pre-mRNA (PubMed:33372658).  Plays a role in the association of the dosage compensation complex proteins dpy-27 and sdc-3 with the hermaphrodite X chromosomes (PubMed:16139225, PubMed:17720939).  Binds to 5'-UGCAUG-3' elements in intron 7 of the pre-mRNA of unc-32 to promote its alternative splicing in neuronal tissues (PubMed:23468662).  Binds to 5'-UGCAUG-3' elements in intron 4 of the pre-mRNA of egl-15 to promote its alternative splicing in body wall muscle tissues (PubMed:17060915).  Promotes binding of RNA-binding protein sup-12 to target RNA (PubMed:17923701).  Plays a role in male mating behavior (PubMed:9927456).
What are the official names of this protein?
Sex determination protein fox-1, Feminizing locus on X protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEPA_BUCBP
Sequence: METIRNFSIIAHVDHGKSTISDRLIQICGGLSKREMHSQVLDSMDLEKERGITIKSQSVTIEYKSKCNKIIQMNFIDTPGHVDFSYEVSRSLSACEGALLIIDATQGVEAQTIANCHTALDMNLKVIPILNKIDLPTADPQRVKKEIEDIIGLSTNNIILCSAKTGTGITNLLETITHNIPYPKGNPNDPLQALIIDSWFDCYLGVVSLVRVKNGYLTKKTKIQIMSTKKIYNIEKIGIFTPKPIFKDILKCGEVGWIICGIRNITGAPVGDTITQHPNSAKKVLSGFKKIKPKIYAGLFTIQSNQFSLFRDALGKLSLNDASLFYEPEHSLALGHGFRCGFLGILHMEIVQARLEREYNLQIIATSPTVIYKIIMIDNTNYYLDTPHKLSTLQKIKEIREPIAKCLILLPIKYLGNTLLLCSQRRGVQNDISYYNNQILLDYSIPMSEVVLNFFDQLKSVSSGYASLEYNFELYKVAHVKCLDILVNYKKIDSLSTIVHKTKILNQAKNVVEKMKNLIPRHQFDIIIQAVIGTKVIVRTTIKQLRKNVLAKCYGGDVTRKKKLLKKQKIGKKRMKQIGNITIPQEVFLKILNNN
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PI16_HUMAN
Sequence: MHGSCSFLMLLLPLLLLLVATTGPVGALTDEEKRLMVELHNLYRAQVSPTASDMLHMRWDEELAAFAKAYARQCVWGHNKERGRRGENLFAITDEGMDVPLAMEEWHHEREHYNLSAATCSPGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHCKNSLCEPIGSPEDAQDLPYLVTEAPSFRATEASDSRKMGTPSSLATGIPAFLVTEVSGSLATKALPAVETQAPTSLATKDPPSMATEAPPCVTTEVPSILAAHSLPSLDEEPVTFPKSTHVPIPKSADKVTDKTKVPSRSPENSLDPKMSLTGARELLPHAQEEAEAEAELPPSSEVLASVFPAQDKPGELQATLDHTGHTSSKSLPNFPNTSATANATGGRALALQSSLPGAEGPDKPSVVSGLNSGPGHVWGPLLGLLLLPPLVLAGIF
What is the function of this protein?
May inhibit cardiomyocyte growth.
What are the official names of this protein?
Peptidase inhibitor 16, PI-16, Cysteine-rich secretory protein 9, CRISP-9, PSP94-binding protein.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_RICAE
Sequence: MLYNLLLPHIHNSHIANLFHYITFRGGLAIIITLSLSFITGPILIEFLRSLQKNGQPIRSDGPESHQTKVGTPTMGGIMIILSSCLSTLLLADLTNKYIWITLFGFISFGIIGFMDDYAKVTKDNHYGVRGKSKLLLQGIISFIICVLLEYLDKSPSHLLNVPFFKNLSLDLGYCYIVFAIFVIVGSSNAVNLTDGLDGLATVPIAFTAGSFALISYLVGNLIYSNYLQLTYIPNTGELTVLCAGLVGSCLGFLWFNAQPAEVFMGDTGSLSLGGVLGIISVITKHEIVLAIVGGLFVIETASVILQVYYFKATKGKRIFKMAPLHHHFEKHGWAESKVVIRFWIISVIFALIGLSSLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL7_NEIMB
Sequence: MAITKEDILEAVGSLTVMELNDLVKAFEEKFGVSAAAVAVAGPAGAGAADAEEKTEFDVVLASAGDQKVGVIKVVRAITGLGLKEAKDIVDGAPKTIKEGVSKAEAEDIQKQLEEAGAKVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CRCB_DEHMB
Sequence: MGEILLLAAGGALGAVSRYGLNNLTVKLLGDSFPYGTLIVNCLGCFVLGFLMQWGFSSDSHNTHLKLMLTAGFLGAFTTFSTFSYETLDCFKNGDYFNGFSNILANVLLGLLMVFIGAYLGSLLKQNSGT
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLBLA_DICDI
Sequence: MRVIRSLLLLTIAIIGSVLSQSSIDDGYTVFYSQPDNYYVKPGTFSNGVAQAIFSNEMMTTGWSFMSISSSEGLYPNDIIAAGAGYLEGYISQEMIYQNWMNMYNNEYHNVIGSDVENWIQENLQYLQTMIDSAPSNDLYWQNVETVLTQITYMQRGYNQSVIDNGVDASQSLGITEFFLMNMDGDMIDLGPALNLTNGKQVTSPATATSPKQAFKEFMRRTGHCSALIKMTDDLSDLFSGHTTWSSYYEMVRMFKVYNLKYLFNGQPPASKVTMFSGYPGTLSSIDDFYLLDTKIVVIETTNGLMNNNLYHLITSESVLSWIRVIVANRLATGGESWCQTFSLYNSGTYNNQWIIVDYNKFIKGYGALDGTLYILEQVPDYVEYGDQTAILRTGYWPSFNIPFYENIYGLTGFNETYAQFGNWFSYQASPRSMIFKRDANNIHSLTQFQAMLRYNNWQNDPFSQGNAGNQISSRFDLVTADDPNNQYLDPDAFGGIDSKVVSADMVAALLVNAQSGPSHDNETPFTWNSQWNQKYTYAGQPTTWNFDWMTMSLQSMKPASPSSDSSSDSTTFN
What is the function of this protein?
Phospholipase that removes both fatty-acid chains from phosphatidylcholine and produces the water-soluble glycerophosphorylcholine.  In addition to phosphatidylcholine deacylation, it also hydrolyzes phosphatidylinositol and phosphatidylethanolamine.
What are the official names of this protein?
Phospholipase B-like protein A.
What is the protein family that this protein belongs to?
Belongs to the phospholipase B-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: TYW4_CANAL
Sequence: MTSTSKLDANQLARQRKKLEKDRRKKVYDDQQVQGTNNSSIVSKRSVEKLYTQVLQPELGEWFQYFVPKGKRRSPAINRGYWIRMESIRQMVIRIIKANSPNVRINVVNLGCGFDPLAFQLLSLFKNQYNLNFIDIDYPDLVKNKYNMIQQSDEIKQLIGDQGSKSSDLYVMETDNYQLVGCDLKNLAYYKEILPKLVSRNVDPHPTSINIFIAEVSLAYMKPQFANPVIEISSQVNNSHFLILEQIMPDGATNAFATKMLYHFQHLRSPIQCVETYPTEKLQLQRFKRYYKHAEIKNLYGNWKFLIDYQMQKNISTIEEFDEWEEFIIFCQHYVIVHATHMDQLIYDDESSEEQKNEKAFSEMSLDSSVAISHDDRFNDEQLQLKFPAIASFKDKIYVNGGLKQTRNDENLEIDLQTGVITKLDQTENLPTARMCHTLTNLGENLVLIGGRSRPGVFFKDVYMFDTAKKWTRLADLPVGRSRHATVKISDHEVLIFGGLDASSSTTGDELFLLCNTNTNSYTPVKPIGDNDNHPIKNLQSACMIFDGKQGYIFGGMEDINVPIVNSKLYRFELVGENNISVTKVFDHSLLKRIGSKAHILENGDKLLIVGGVSPDQLFTKSTNIVTLDLNIFTFKSVEIPNVISEKVPPIFVGFELVQINNKASYIISGGAVCYSFGSCYNSVYKLEY
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues (By similarity).
What are the official names of this protein?
tRNA wybutosine-synthesizing protein 4, tRNA-yW synthesizing protein 4, Leucine carboxyl methyltransferase 2, tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase, tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: ILVM_ECOL6
Sequence: MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQNINIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA
What are the official names of this protein?
Acetolactate synthase isozyme 2 small subunit, ALS-II, Acetohydroxy-acid synthase II small subunit, AHAS-II.
Protein: GCH1_LEPIN
Sequence: MEEDVINILKSIGEDPTREGLLNTPKRVKKAYEFLTSGYRADITKIVNGAIFEEPTEGMVLVRDIEMYSLCEHHLLPFYGKAHVAYLPNKKIIGISKIPRIVDVFARRLQVQERLTEQIAYAIQEVLDPQGVAVVIKAKHLCMMMRGVEKQNSELFTSCMLGAFKENMVTRSEFLDLIRTGST
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: ATPL_VIBVU
Sequence: METVLSFSAIAVAIIVGLCALGTAVGFAVLGGKFLEGAARQPEMAPMLQVKMFIIAGLLDAVPMIGIVIALLFTFANPFVGQLAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUTA_METED
Sequence: MNIGVFIPIGNNGWLLSENAPQYMPSFELNKQITLKAEQHGLDFVLSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIKLYATAPTLCLPPAIVARMASTIDSISNGRFGLNLVTGWQRPEYAQMGLWPGDEYFGRRYEYLSEYAQVLRELWETGRSDLKGEFFQMEDCRLSPRPQAEMKIICAGQSAAGMAFTATYADYNFCFGKGVNTPTAFAPTVERLEEAKAKTGRDVSSYVLFMVISDETDEAARAKWEHYKAGADAEAIAWLGLQGAADTKSGADTNIRQMADPTSAVNINMGTLVGSHATVAALLDEVVTVPGTGGVLLVFDDFLKGLDDFGTKIQPLMRSRRHVTGEALAEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: ISPG_BACP2
Sequence: MSEVTHRTKTRPVKVGPLTIGGNNEVVIQSMATTKTHDVEATVAEIKRLEEAGCQIVRVACPDERAANAIADIKKQINIPLVVDIHFDYKLALKAIEAGADKIRINPGNIGRREKVEAVVKAAKEKGIPIRIGVNAGSLEKKILDKYGYPTADGMVESALHHIKILEDLDFHDIIVSMKASDVNLAIEAYEKAAKAFDYPLHLGITESGTLFAGTVKSAAGLGAILNMGIGNTLRISLSADPVEEVKVARELLKSFGLAANAATLISCPTCGRIEIDLISIANEVEEYISTIKAPIKVAVLGCAVNGPGEAREADIGIAGARGEGLLFRKGEIVRKVPEETMVEELKKEIDKIAEEHYAKMEAEKAKANA
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: IF2A_BOVIN
Sequence: MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSINKLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLEYTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNINRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTTTLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEVDGDDDAEEMEAKAED
What is the function of this protein?
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.  This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex.  Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.  EIF2S1/eIF-2-alpha is a key component of the integrated stress response (ISR), required for adaptation to various stress: phosphorylation by metabolic-stress sensing protein kinases (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2) in response to stress converts EIF2S1/eIF-2-alpha in a global protein synthesis inhibitor, leading to a attenuation of cap-dependent translation, while concomitantly initiating the preferential translation of ISR-specific mRNAs, such as the transcriptional activators ATF4 and QRICH1, and hence allowing ATF4- and QRICH1-mediated reprogramming.
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
What are the subcellular locations of this protein?
Cytoplasm, Stress granule. Note=Colocalizes with NANOS3 in the stress granules.
Protein: ATPB_RAPSA
Sequence: MRTNPTTSDPAVSIREKNNLGRIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTLGQEINVTCEVQQLLGNNRVRAVAMSATEGLKRGMDVVDMGNPLSVPVGGATLGRIFNVLGEPVDNLGPVDTSTTSPIHKSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTSLIMELINNIAKAHGGVSVFGGVGERTREGNDLYKEMKESGVINELNLAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGTLQERITSTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQQVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFKLILSGEFDSLPEQAFYLVGNIDEATAKATNLEMESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TOS6_VANPO
Sequence: MKFSTVAATIASTFAVASAASESVTYVDITVTPEVTTSMVSTVKVTSTPYTTTTLSFAVQSNSVSHNETTSNSTQTTTVSLFEGAGNTAQVGAGALVAAVAAALLL
What are the official names of this protein?
Protein TOS6.
What is the protein family that this protein belongs to?
Belongs to the TOS6 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Protein: THII_PEDPA
Sequence: MKYTEIMVRYGELSTKGKNRKDFIARLGGNIRKSLKDFEDVEIHPNRDRTHVTLNGTDSDAVINRLKKVFGIQNFSPMLKVEKTMEAVQAGALEMMKEQLKPGMTFKINTRRSDKEFAINTDTMNRELGGFILDNFPDNDVKMKNPDITLRVEIRSNGIFLTSEVINGAGGLPVGTAGKGMMMLSGGIDSPVAGYLGMKRGVEMEMVHFFSPPYTSEQALAKAKELSGKLAAYSGSVQFIQVPFTEIQETIKEKCPEGYLMTIQRRMMLRLVVALAKQRGGLAIFNGESLGQVASQTMESMLAINDVTTMPIIRPVVSMDKNEIIDIAKDIDTYDLSIMPFEDCCTIFAPPSPKTHPDLEKTRYFEKRIDVEGLLERSLAGVKITNIRAEENFMNQNEEVFAELL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_BLOFL
Sequence: MKVRASVRKMCQHCFIIKRRNVIRVVCRVTPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: URK_STRPS
Sequence: MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGP3_ARATH
Sequence: MFAQLAPSPSPSPANVSHFVHRRTFRQCTYAVSASLPTANSSRPPPIQIVGGKDLNLDVTRKDDSIGFKLEANEDEIDWMNLESDIRLWTRALRPVQWYPGHIMKTEKELREQLKLMDVVIEVRDARIPLSTTHPKMDAWLGNRKRILVLNREDMISNDDRNDWARYFAKQGIKVIFTNGKLGMGAMKLGRLAKSLAGDVNGKRREKGLLPRSVRAGIIGYPNVGKSSLINRLLKRKICAAAPRPGVTREMKWVKLGKDLDLLDSPGMLPMRIDDQAAAIKLAICDDIGEKAYDFTDVAGILVQMLARIPEVGAKALYNRYKIQLEGNCGKKFVKTLGLNLFGGDSHQAAFRILTDFRKGKFGYVSLERPPL
What is the function of this protein?
GTPase that may function in chloroplast ribosome assembly (Probable).
What are the official names of this protein?
DAR GTPase 3, chloroplastic, Protein EMBRYO DEFECTIVE 3129.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VSGP_EBOSU
Sequence: MGGLSLLQLPRDKFRKSSFFVWVIILFQKAFSMPLGVVTNSTLEVTEIDQLVCKDHLASTDQLKSVGLNLEGSGVSTDIPSATKRWGFRSGVPPKVVSYEAGEWAENCYNLEIKKPDGSECLPPPPDGVRGFPRCRYVHKAQGTGPCPGDYAFHKDGAFFLYDRLASTVIYRGVNFAEGVIAFLILAKPKETFLQSPPIREAVNYTENTSSYYATSYLEYEIENFGAQHSTTLFKIDNNTFVRLDRPHTPQFLFQLNDTIHLHQQLSNTTGRLIWTLDANINADIGEWAFWENKKISPNNYVEKSCLSKLYRSTRQKTMMRHRRELQREESPTGPPGSIRTWFQRIPLGWFHCTYQKGKQHCRLRIRQKVEE
What is the function of this protein?
Viroporin that permeabilizes mammalian cell plasma membranes.  It acts by altering permeation of ionic compounds and small molecules.  This activity may lead to viral enterotoxic activity.
What are the official names of this protein?
Pre-small/secreted glycoprotein, pre-sGP.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
[Small/secreted glycoprotein]: Secreted. SUBCELLULAR LOCATION: [Delta-peptide]: Secreted.
Protein: HCP_MICAN
Sequence: MFCEQCEQTASGNGCHQWGACGKSPEVNAVQDLLVYCLRGLASVVLKAKEAAISTREADIFTCESLFATMTNVNFDQRRFTDYIQRCLEIRENLKAQLGSLDWSALANYQPNFNESLVSQGQEVSLELIEKVQDLDIFSLKLTAIYGVKGLASYTFHAQELGQEDDSVYQVIQETLVAIDRSDLNLNDWVAICLKVGAANLRAMELLDQGHTETYGHPIPTNVPLNPRLGKAILVSGHDIKQLAALLAQTANTGITVYTHGELLPAHGYPKLKEKYPHLYGHYGTAWQNQTKEFAKFPGAIVLTTNCLMPPHENYESKLFTLGPVGYAHINRLETVDGAIDFSPVIAKAQSLLGFTEISEPRQVMVGFAHNTVLSVADTVVNALKQGKIRHFFLVGGCDGAKPDRNYYTEFVEQVPEDCIVLTLACGKFRFFDKQLGSIEGLPRLMDLGQCNDAYSAIKIALGLANAFNVSVNEIPLSLIISWYEQKAIAVLLTLLHLGMQNIRLGPTLPAFISPNVLKFLSDTYHLQPITTPAKDLADCLG
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_GLUOX
Sequence: MSAPATSPSAPTRPLLAIETSCDDTACAILAWDGTILAEGVLSQTDHAILGGVVPEIAARAHLDALPALVAEVLKKASLTLADIDTFAGTTGPGLIGGLIVGSSYAKGLAMALHRPFVAVNHIEAHILTPRLPSLGADLHFPYLTMLVSGGHCQCVSVEETGRYVRLGGTIDDAAGEAFDKVAKMLGLSWPGGPALEKLATEGRDDAYPLPRPLKGREGCDFSFSGLKTAVSRLIDTQDPTGSRDALPRQFAADVAASFQRAVADVMADRAEHALALSPNATALVVAGGVAANKTLRHALEQVAANHGIPFFAPPLRLCTDNAVMVAWAALERLHAGETPNEIDTAARPRWPLSERTPATPEHVS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJGA_ECOBW
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: RL331_STAA8
Sequence: MRVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MURC_DESDA
Sequence: MNSKIRHIHMVGIGGAGMSGIAEVLLNLKYEISGSDMSDSAVVRHLRSLGARIAVGHAAENVGDVQVLVKSTAISDDNPELVEARKRNIAIIPRAEMLAELMRLRQGIAIAGTHGKTTTTSLTASIFDEAGLDPTVIIGGRLNVYGANAHLGHGEYLIAEADESDGSFLCLLPIINVVTNVDEDHLDHYKTREAINSAFVQFMNNVPFYGLNIVCGDDPGVLELLPQVKRPVLTYGFAEDNALRAVPLESGRISRFQVWLHDEKLGEVSLPQPGRHNILNALASIGAAMEVGISFEKCAAGLCGFKGVGRRFEFKGEKQGVTVVDDYGHHPAEIAATLATARQVFEGRRIVAAFQPHRFSRTEAHFGEFCKVFNNVDQLLLTEIYAASENPIPGVSGQSLAQGIRQVSSTPVEYFQTLDDLARALPDILQEGDVLLTLGAGNITRLGPTWLEGLDHA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.