PharMolix/UniProtQA huggingface dataset:
Protein: A85A_MYCBP
Sequence: MQLVDRVRGAVTGMSRRLVVGAVGAALVSGLVGAVGGTATAGAFSRPGLPVEYLQVPSPSMGRDIKVQFQSGGANSPALYLLDGLRAQDDFSGWDINTPAFEWYDQSGLSVVMPVGGQSSFYSDWYQPACGKAGCQTYKWETFLTSELPGWLQANRHVKPTGSAVVGLSMAASSALTLAIYHPQQFVYAGAMSGLLDPSQAMGPTLIGLAMGDAGGYKASDMWGPKEDPAWQRNDPLLNVGKLIANNTRVWVYCGNGKPSDLGGNNLPAKFLEGFVRTSNIKFQDAYNAGGGHNGVFDFPDSGTHSWEYWGAQLNAMKPDLQRALGATPNTGPAPQGA
What is the function of this protein?
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M. tuberculosis to murine alveolar macrophages (AMs).  They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor).  They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM.  FbpA mediates triacylglycerol (TAG) formation with long-chain acyl-CoA as the acyl donor and 1,2-dipalmitoyl-sn-glycerol (1,2-dipalmitin) as the acyl acceptor.  It has a preference for C26:0-CoA over C18:1-CoA (By similarity).
What are the official names of this protein?
Diacylglycerol acyltransferase/mycolyltransferase Ag85A, DGAT, Acyl-CoA:diacylglycerol acyltransferase, Antigen 85 complex A, 85A, Ag85A, Fibronectin-binding protein A, Fbps A.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial A85 antigen family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cytoplasm.
Protein: IXTPA_XANAC
Sequence: MKQLVLASGNAGKLEELRAMLAGLPLRVVAQGELGVEDVPETGLTFVENALIKARHASAVTGLPALADDSGLIVDALDGAPGLYSARYAGSPTNALANNAKLLDAMREVPSDRRSARFYAVIVLLRHPEDPQPLIAEGSWEGVITTQPRGDGGFGYNPVFLDPVYGLTAAEMDTALKNRLSHRAVALATLQHKLHAMSL
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: PVK22_PERAM
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2.2, Lem-PVK-2-like peptide, Periviscerokinin-2, PerAm-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MDM12_DEBHA
Sequence: MSFDINWSELVSDESLNESIKEFLDNQFQSISLPSFIDNLSVSDFSLGNSPPEITIRHIGDPFDDFYEDEGDDDEKERKNVYMQQGVSEDTNSSDDDEDDEYDGDRSNDLSIITEDPNIHTFTSEADRSRLASPPRPPLTDLRRSRASSDPFSLIMGNNNLNYMHNYNMNYVGLGNLNATGTHTGTDTPTNILNQNPYATLKSNPSSYYKNKDPSKFSGSDTHKNGFRLTSKEPCSTRGENDIQLIAEVKYNGDLHLELTVNLLVNYPSPNFISLPIKLHVTDLVIHSIITIAYLKNSVFFSFLCDVNDINSDYFTSSTQNSTPEHMGATNTGGNFVDYVSGPINRERIDIIKKVKIESEIGEAEQNALRNVGKVERFLVEQLRNIIRDEFAWPSWVCFDLNEDDDDESDDQEEN
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: CBNB_CUPNE
Sequence: MKIEAISTTIVDVPTRRPLQMSFTTVHKQSYVIVQVTAGGLVGIGEGGSVGGPTWGSESAETIKVIIDNYLAPLLIGKDASNLSEARALMDRAVTGNLSAKAAIDIALHDLKARALNLSIADLIGGTMRKSIPIAWTLASGDTARDIDSALEMIEARRHNRFKVKLGARTPAQDLEHIRSIVKAVGDKASVRVDVNQGWDEQTASIWIPRLEEAGVELVEQPVPRANFGALRRLTEQNGVAILADESLSSLSSAFELARDRAVDAFSLKLCNMGGIANTLKVAAIAEAAGISSYGGTMLDSTVGTAAALHVYATLPSLPYGCELIGPWVLSDRLTQQDLEIKDFEVHLPVGSGLGVDLDHDKVRHYTRAA
What are the official names of this protein?
Chloromuconate cycloisomerase CbnB, Muconate cycloisomerase II CbnB.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: MS152_CAEEL
Sequence: MTQSVPPGDIQTQPGTKIVFNAPYDDKHTYHIKVINSSARRIGYGIKTTNMKRLGVDPPCGVLDPKEAVLLAVSCDAFAFGQEDTNNDRITVEWTNTPDGAAKQFRREWFQGDGMVRRKNLPIEYNP
What is the function of this protein?
Central component in molecular interactions underlying sperm crawling.  Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
What are the official names of this protein?
Major sperm protein 152, MSP.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasm, cytoskeleton.
Protein: PMEPA_XENLA
Sequence: MHNLMGLNSTSESIHSNVSCTCNCKRSLFQTMEISELEFVQIIIIVVVMMVMVVVITCLLNHYKLSARSFIHRHSQGRRREENLSSEGNLWPSESTVSGNGIIEQHIYTPRPSDRLSVPSFLQRDRFNRFQPTYPYIQNEIDLPPTISLSDGEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDSSVYGGPCPPSSNSGVSATSYSSNGRMEGPPPTYNEVIGHYPRSSFYHCQQPNLATPSILESNRLQPGNHGLDSTITRSKDKDKQKGQPF
What is the function of this protein?
May function as a negative regulator of TGF-beta signaling and thereby inhibits activin-mediated mesoderm formation.
What are the official names of this protein?
Protein TMEPAI, Prostate transmembrane protein androgen induced 1, Transmembrane prostate androgen-induced protein.
What is the protein family that this protein belongs to?
Belongs to the PMEPA1 family.
What are the subcellular locations of this protein?
Early endosome membrane; Single- pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.
Protein: KS6A2_CAEEL
Sequence: MEDILMPEGEKVSMENFALLRVLGKGAYGKVFLVRKVGGKDHNTIYAMKVLRKTRVLTKQKTLEHTMAERQVLERLRGTPFLVNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRGHFDLEAARFVIAELVVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLFLPGELDRANSYCGTIEYMSPEVINRPEGGYSDVVDWWSLGVISFELLTGCSPFTVDGAQNSSKDIAKRIMTKKVPFPKTMDVDARDFIGQLLEKKLEKRLGYNGVDEIKNHKFMSSIDWDAAVKRTLKPVIVPRIGHDLDTQFFSAEFTSQPPLYSPAESPLNANTLFRGYSYVSPSVIFANDNVIGEELMAEDVNALLASSSFFAKYKLDKSDAGLLGKGAFSVVRRCERVVDGAQFAVKIVSQKFASQAQREARILEMVQGHPNIVQLHDVHSDPLHFYLVMEILTGNELLERIRKLERFTESEAADIMRQLVSAVKYLHDKRIVHRDLKPENILFESIDSSARLRLVDFGFARLLPNSMEQQLKSVQVLRKMTPCFTLQYAAPEVLDVGDSQPEYNEQCDLWSLGVVLFTMLSGQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAKNLITGLLTVDPKKRLSMQELTAHMWLKSSASMDTPLQTPSILPSSADETFNETLRAFLHANRDGFHLLDVAAAPLMKRRGIKRQSGDKDASGNSKNSRVTQFECLPEEQEAEMTSSTSRPSNLGMMNYREPNSGTIRETRGSDSS
What is the function of this protein?
Serine/threonine kinase that may play a role in mediating the mitogen- and stress-induced effects on transcription.  May repress transcription via phosphorylation of 'Ser-1' of histone H2A.  May phosphorylate histone H3 (By similarity).
What are the official names of this protein?
Putative ribosomal protein S6 kinase alpha-2, Ribosomal protein S6 kinase alpha-5 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Protein: PG170_VAR67
Sequence: MYSLVFVILMCIPFSFQTVYDDKSVCDSDNKEYMGIEVYVEATLDEPLRQTTCESEIHKYGASVSNGGLNISVDLLNCFLNFHTVGVYTNRDTVYAKFTSLDPWTMEPINSMTYDDLVKLTEECIVDIYLKCEVDKTKDFIKTNGNRLKPRDFKTVPPNVGSIIELQSDYCVNDVTAYVKIYDECGNIKQHSIPTLRDYFTTTNGQPRKILKKKFDNC
What is the function of this protein?
May interact with several cellular chemokines to interfere with chemokine-glycosaminoglycan (GAG) interactions at the cell surface to alter chemotaxis of nearby responsive cells.
What are the official names of this protein?
Protein OPG170.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG170 family.
Protein: UXAC_PECAS
Sequence: MPQFLSEDFLLDTEFARRLYHEYAVDQPIFDYHCHLPPEQIAENYRFKNLYDIWLKGDHYKWRAMRTNGVPERLCTGDASDWEKFEAWAATVPHTIGNPLYHWTHLELRRPFGVTGTLLSPSTAKGIWDRCNAMLERDDFTARGIMQQMNVKMVGTTDDPIDDLRHHKAVAQDSSFSIKVLPSWRPDKAFNIELATFNDYMAKLGEVSDTDIRRFSDLQTALTKRLDHFAAHGCKVSDHALDVVMFAEADDATLDKILARRLAGETLSEHEVAQFKTGVLVWLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPLAQELSRLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMQRQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEDGEAPADLPLLGEMVKNISFDNAKNYFAIEL
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: GPPA_PSET1
Sequence: MGQLKPQKNVYAVIDLGSNSFHMLIAKSIAGGLQTIGRVKRKVRLAAGLDIDNVLSSEAMHRGWECLALFAERLQDIPKQNITIVATATLRLASNADVFKAQAEKILGHKVNVISGELEARTIYKGVAHTSSCTGSQLVIDIGGASTEVIIGKNFDALLYKSLNIGCVTYLERYFKDCKLSNANFNTAIKAARTVIDEIASEYKVKGWQIASGASGTVQAIQEIMIAQNLDELLTLEKLYTIKKQSIAYKTIAALDLPGLSEDRRLVFVSGLAILIALFESLEIEKMGLAGGALREGVLYSMLPELHNSDIRKRTIDGFIDRYHVDQKQASRVASLVLNLASEVNESWPIKALNGLPLLTAVAQLHEIGLLIEYKQYHKHSAYILKNTEMPGFSQSEHKVIVAVAKGHRSDLQKGYFDSLGANSVLAQYLVRLIRIAVILCMRRQDDVLPEFAITVKDDVLNLQFENDWLKNHPLMASELQQESKQQAKLGWKLIVN
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: RUSD2_HUMAN
Sequence: MWLDRRGWLRVLGHWRYDLRRPSFTRTWSGDKGPMAETVSTQVGTEGGLRASHQQNGDAGGDAKVELSPGPPKPAGREVEPAPVGGEHPSAAAPGPGKHKKRRGATRERVVPPPKKRRTGVSFGDEHFAETSYYFEGGLRKVRPYYFDFRTYCKGRWVGHSLLHVFSTEFRAQPLAYYEAAVRAGRLQLNEKPVQDLNIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENEDVVVVDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSERIHEQVRDRQLEKEYVCRVEGEFPTEEVTCKEPILVVSYKVGVCRVDPRGKPCETVFQRLSYNGQSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIYNSVAWGPSRGRGGYIPKTNEELLRDLVAEHQAKQSLDVLDLCEGDLSPGLTDSTAPSSELGKDDLEELAAAAQKMEEVAEAAPQELDTIALASEKAVETDVMNQETDPLCAECRLVRQDPLPQDLVMFLHALRYKGPGFEYFSPMPAWAQDDWQKD
What is the function of this protein?
Pseudouridine synthase that catalyzes pseudouridylation of mRNAs.
What are the official names of this protein?
Pseudouridylate synthase RPUSD2, RNA pseudouridylate synthase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: PHMT_MYCTA
Sequence: MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEEDPPMDLPLEASDEPNRAHINLYHRTATQVDLGGKQVLEVSCGHGGGASYLTRTLHPASYTGLDLNQAGIKLCKKRHRLPGLDFVRGDAENLPFDDESFDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNNEIAAWEADLAATPLRQLSQRQINAEVLRGIGNNSQKSRDLVDRHLPAFLRFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD
What is the function of this protein?
Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL).
What are the official names of this protein?
Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase family.
Protein: DEOC2_STAAN
Sequence: MNSAKLIDHTLLKPESTRTQIDQIIDEAKAYHFKSVCVNPTHVKYAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRFDDVQQDIEAVVKAAKGHTVKVIIETVLLDHDEIVKASELTKVAGADFVKTSTGFAGGGATAEDVKLMKDTVGADVEVKASGGVRNLEDFNKMVEAGATRIGASAGVQIMQGLEADSDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase 2, DERA 2, 2-deoxy-D-ribose 5-phosphate aldolase 2, Phosphodeoxyriboaldolase 2, Deoxyriboaldolase 2.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_BRUA2
Sequence: MAEAKALPRFKKLYQDNIRKALLEEFKYDNEMQIPRITKVVLNMGVGEATGDSKKPAVAAEDLAMIAGQKAVVTRARNSIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNPKSFDGRGNYAMGIKEHIVFPEINYDKVDQIWGMDIIVCTTAKTDDEARSFLRAFNFPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: FABV_SHEB2
Sequence: MIIKPKIRGFICTTTHPVGCEANVQEQITLTKAKGKIANGPKKVLVVGSSSGYGLSSRIAAAFGSDAATIGVFFEKPGTETKPGTAGWYNSAAFDKFAKAEGLYSKSINCDAFSHEAKQKVIELIKQDLGEIDMVVYSLASPVRKLPDSGELIRSALKPIGETYTATAVDTNKDCIIEATVEPATEQEIADTVTVMGGEDWELWIKALSEAGVLADNCKTVAYSYIGTELTWPIYWHGALGKAKMDLDRAAKALNEQLSATGGSANVAVLKSVVTQASSAIPVMPLYIAMVFKKMRQEGLHEGCMEQIYRMFSERLFRADGAKPETDSDNRIRLDDWELREDIQQHCRNLWPQVTTENLSELTDYREYKAEFIKLFGFGIEGIDYDADVNPYVEFDVIEL
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: SECA2_GEOTN
Sequence: MLSLLKRAIGYTNERQLKKYMRVVEQINRMEPQMEKLTDAELRRKTDEFKEQLASGKSVNDIQVEAFAVVREVAKRVLGMRHFDVQLIGGLVLAEGNIAEMATGEGKTLVASLPSYLRALEGKGVHVITANDYLAKRDRNLIGQIHEFLGLTVGLNLPLMSPQEKKQAYQADITYGIGTEFGFDYLRDHMVYDASDKVQRPYHYAIIDEIDSVLIDEAKTPLIIAGKTRSSTELHYIAARLVKRFEREVDYIYDGETKTVNLTDEGIEKVEKAFGIDNLYDAEHQVLYHYVIQALRAHVLFQRDVDYIIRDGKVLLVDAFTGRVMEGRSLSDGLHQAIEAKEGLEITEENKTYASITIQNYFRMYPILSGMTGTAKTEEKEFQRIYGIDVIPIPTNRPKIRVDLPDRVYMTRHDKYVAVAKEVKRRHESGQPVLIGTTSILQSEEVAKYLDQEQVPYELLNAKTVEQEAEVIARAGQRGRVTIATNIAGRGTDILLGEGVNELGGLHVLGTERHESRRIDNQLKGRAGRQGDPGSSQFFISLEDDMFRRFAAEETEKLKAKLKTDETGCILNNDIHEFVDKVQRIVEGMNFSVREYNLKLDDVMNEQRNVIYQIRDRVLEENDRVALVVPMIRSACDRIVDAYALSEQIPEEWDVRRMTEELNRIVYRTPITFDQPPADLEDVKRKVAEAVESYVALLEKKKAHTQLQTLLKSVMLTVIDDYWMRHLDQMALLKEGIGLRHYQQEDPIRLYQKEGFEMFKAMYEVIEKEISVHTARLLQSLEQEEGQS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: TPIS_PHOLL
Sequence: MRHPLVMGNWKLNGSTHMVNELITGLRQELSSVTGCDVAIAPPALYLSQAKQALAGSRIALGAQDVDVNLSGAFTGETSATMLKDIGAEYIIIGHSERRTYHQESDEFIAKKFAILKQQGLIPVLCIGETEQENEAGQTESVCARQIDAVLNTLGVAAFQGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAQKDAAIAQQIIIQYGGSVNADNAAELFSQPDIDGALVGGASLKANAFAVIVKAAAAAKKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_ECODH
Sequence: MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: KRR1_DROWI
Sequence: MSDSESEEATKINTDPVDNAWSLKIPAFKETDNPHGMIEESSFATLFPKYREKYLKEVWPLVEQAVGEHHLKAELDLVEGSMVVKTTRKTWDPYIIIKARDMIKLMARSVPFEQAKRVLQDEIGCDIIKIGNLVQKKEKFVKRRQRLIGPNGATLKSIELLTDCYVLVQGNTVSALGPYKGLQQVRDIVLETMNNVHPIYNIKALMIKRELMKDPKLANEDWSRFLPKFKNKNLSKRKQPKVKKPKKEYTPFPPAQPESKIDKQLASGEYFLNKEQKQAKRQQERQTKQAEAAKKQDERRNKDFIPPTEEPPTGSKRKANDNDSSDSRVDVQSLKAKLLKANKKSKS
What is the function of this protein?
Required for 40S ribosome biogenesis.  Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.  Binds to RNA.  Required for female germline development, cell viability during eye development and for survival of dividing cells and epithelial cells during early wing disk development (By similarity).
What are the official names of this protein?
KRR1 small subunit processome component homolog, KRR-R motif-containing protein 1, Protein dribble.
What is the protein family that this protein belongs to?
Belongs to the KRR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RS9_DESRM
Sequence: MAQVQFYGTGRRKNAVARVYLVPGEGKVVVNNKEVLDYFGRKTLDMVVRQPLELTNTTGRFDVLVKVVGGGVSGQAGATRHGLARALVQADPNLRPVLKRAGFLTRDPRMKERRKYGLKKARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ADHS2_ARCFU
Sequence: MTKIGKKIRIERIINRESRNTVIVPMDHGVSMGPIEGLKNLAETVNAVAEGGANAVVLHKGVVGFGHRGYGKDVGLIIHLSASTSLAPDPNEKVLVCTVEEAIKLGADAVSVHVNVGSKTEAYQLRKLGEISKIAGEWGMPLLAMMYPRGDGINQFDEKAVALAARVGAELGADIIKTNFTGDVESFRRVVDGCPVPVVVAGGPKMGSDEDILRMVRMAMDAGARGVAIGRNIFQANNPTKMTRAISMIVHDNADVSEALEFLKS
What is the function of this protein?
Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH).  Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
What are the official names of this protein?
Putative 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase 2, ADH synthase 2, ADHS 2, ADTH synthase 2.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
Protein: DUT_SALCH
Sequence: MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELAPGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RSMH_NEIG2
Sequence: MSGAESYRHITVLLNEAVDALAVREDGVYVDGTFGRGGHSRLILSRLGDAGRLIVFDKDPQAIAVAEELARSDKRVGVVHGGFASFQTALDGLGIGKVDGALFDLGISSPQIDDGSRGFSFRFDAPLDMRMDTTRGMSAAEWIAVASEQDLHEVIKNYGEERFSRQIVRAIVAQRAESPIDTTRKLAQIVAQNVRTRERGQDPATRTFQAIRIFINRELEEVGAVLPQVMCRLKEGGRLAVIAFHSLEDRIVKQFVKKYSQHEPLPSWAAVREADLPEPPLKIVGRALKPGEAEIAANPRARSAVLRVAERTAGPIPE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT4_ANSCE
Sequence: SGSCEFKTCWKAMPPFRKVGNVLKEKFDGATEVEQSEIGSTKVLVPKNSQFKPHTDEDLVYLDSSPDFCDHDLKNGVLGTSGRQCNKTSKAIDGCELMCCGRGFHTDEVEVVERCSCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors (Probable).  Plays an important role in embryonic development (By similarity).
What are the official names of this protein?
Protein Wnt-4.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.