PharMolix/UniProtQA huggingface dataset:
Protein: PTH_MARMS
Sequence: MAGFRLLVGLGNPGSEYENTRHNAGAQWIEALARQSQCSLRSEKKFFGQFGKVYIAGEECYLLIPTTYMNLSGKAVQAVCQFYKIPPEEVLVIHDELDIPPGTAKLKQGGGHGGHNGLKDIISKLANNREFGRLRIGIGHPGHASQVANYVLKKAAPDDYTKIEQAIDESLRYVDDIVRGNLNAVMNQLHSFKA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSHB_AILFU
Sequence: MEMLQGLLLWLLLNVGGVWASRGPLRPLCRPINATLAAENEACPVCVTFTTTICAGYCPSMVRVLPAILPPMPQPVCTYHELHFASIRLPGCPPGVDPMVSFPVALSCRCGPCRLSNSDCGGPRAQPLACDRPPLPGLLFL
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta, Lutropin beta chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_EHRRG
Sequence: MSDTKNLNHDRQKALDNAISQIEKAFGRGAIMKLKQGAIEKIDSIPTGSIALDTALGIGGFPKGRIIEIFGPESSGKTTLALHVIAESQKKGGNCAFIDAEHALDIMYARKLGVNTGDLIVSQPDTGEQALHIVEYLICSGAIDVIVVDSVAALTPRAEIEGDMGDQHMGLQARLLSHALRKLTSIVSKANCILIFINQIRMKIGVVYGNPETTTGGNALKFYSSVRLDIRKVSAIKDKDVIIGNQTKVKVVKNKVAPPFKQVDFDIMYNEGISKVGEIIDMGVKLNIVEKAGSYYSYNSVRLGQGKENAKLYLKNNPSTADEIEQKIRASLQASDNDVSCFNAEVDSISDMDVPVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1661_FUSNN
Sequence: MSGHSKWNNIQHRKGAQDKKRAKLFTKFGRELTIAAKEGGGDPNFNPRLRLAIEKAKAGNMPKDILERAIKKGSGELEGVDFTEMRYEGYGPAGTAFIVEAVTDNKNRTASEMRMTFTRKDGNLGADGAVSWMFKKKGVITVKAEGIDADEFMMAALEAGAEDVTEDDGYFEVTTEYTEFQTVLENLKNAGYQYEEAEISMIPENTVEITDLETAKKVMALYDALEDLDDSQNVYSNFDIPDEILEQLD
What are the official names of this protein?
Probable transcriptional regulatory protein FN1661.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOE_PAPHA
Sequence: MKVLWAALLVTFLAGCQAKVEQPVEPETEPELRQQAEWQSGQPWELALGRFWDYLRWVQTLSEQVQEELLSPQVTQELTTLMDETMKELKAYKSELEEQLSPVAEETRARLSKELQAAQARLGADMEDVRSRLVQYRSEVQAMLGQSTEELRARLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGVSAIRERLGPLVEQGRVRAATVGSLASQPLQERAQALGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQISLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGASTAPVPSDNH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: HTF_EURFL
Sequence: QVNFSPNW
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, EurFl-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: DYM_XENTR
Sequence: MGANSSTIKELSENEFLKKLSGTDSISENEPFWNQLLSFSFSTPTNSADSKLLEEGTLSICKSLIENNPRTGNLGALIRVFLSRTKELKISAECQNQLFIWQAHNALFIICRLIKVFTSQISEEELLLHFTYRPADPGNYESDTENLFEELLFCLIQLIVEIPLLDLTYSILLEAVTALIVLLSYQLFRKDILHESPIHRHLMKGPCLPYTSRLVKTLLYNFIRQEKSPPPGSHIFPQQQDGGGLLYGLASGVASGIWTVLTLGGVGSKPTPQQEQSSPLANQSLLLLLVLSNLTDAPDCPNPFRQSVTFFRNTQDSSVSPTPNPHSFQINFNSLYTALCEQQKSDQATLLLYTLLHQNSNVRTYVLARSDMENLVLPILEILYHVEDRNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYTERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLGSDESPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNMVYALLYKRELFEQFRSHPSFQDIMQNIDMVISFFSLRLEQAGADLSVERVLEVIKQGAVALPKDRLRKFPELKFKYVEEEQPEEFFIPYAWSLVYHSGVGLYWNPQDIQLFTMDSG
What is the function of this protein?
Necessary for correct organization of Golgi apparatus.
What are the official names of this protein?
Dymeclin.
What is the protein family that this protein belongs to?
Belongs to the dymeclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Note=Sequence analysis programs predict 2 transmembrane regions. However, it has been shown in human that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol (By similarity).
Protein: MAM_PINMA
Sequence: ASMFKHDHYMDNGVRYPNGDGICEQLNETKCDAGFSYDRSICEGPHYWHTISKWFIACGIGQRQSPINIVSYDAKFRQRLPKLKFKPHMEKLKTEVTNHQNRAPEFEPEDGENLYVKLNNLVDGHYKFHNLHVHNGRTRRKGSEHSVNGRFTPMEAHLVFHHDDQTHFEPTRTKLGGAFPGHNDFVVVGVFHEVGDDGFGDEPDDEECKRILKGHHPDNNENGNGDNGNNGYNGDNGNNGDNGNNGYNGDNGNNGDNGNNGYNGDNGNNGDNGNNGENGNNGENGNNGDNGNNGENGHKHGCRVKKAKHLSRILECAYRNDKVREFKKVGEEEGLDVHLTPEMALPPLKYRHYYTYEGSLTTPPCTESVLWVVQKCHVQVSRRVLHALRNVEGYKDGTTLRKYGTRRPTQKNKVTVYKSFK
What is the function of this protein?
Acts as a negative regulator for calcification in the shells of mollusks.  May function both as a calcium concentrator and as a carbonic anhydrase required for production of carbonate ions, which are assembled to CaCO(3) at mineralization sites.  Is important for shell formation in both the calcitic prismatic layer and the aragonitic nacreous layerr (By similarity).  Shows inhibitory activity of crystal formation when present in free state but, when attached to the insoluble matrix, may regulate the form and size of aragonite crystal.
What are the official names of this protein?
Nacrein-like protein M.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CB21_PINTH
Sequence: MATASAIQSSSLAGQTLLRPQQNELVKKVGTAQARITMRRTVRSAPESIWYGPDRPKYLGPFSEGTPSYLTGEFPGDYGWDTAAVSADPETFAKNRELEVIHCRWAMLGALGCVFPELLAKNGLKFGEAVWFKAGAQIFSEGGLDYAGNPNLIHAQSILAIWACQVVLMGLIEGYRVGGGTLGEGLDPLLPGGAFDPLGLADDPEACAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPIENLYDHLADPVANNAWAYATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein type I, chloroplastic, CAB, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: RLMKL_ALISL
Sequence: MKKYLAITSKGLENLLADELVALGVTDPKLVYAGVTFEAPIEVVYRCCLWSRIASRFIQILSEFDVRDDMDLYLGASAINWPNYFTADKTLVVDFNGTNREIRNSQYGALKVKDAIVDRFTKADLERPNIDKAEPDLRVHMRLSGEKGILGFDLIGSGLHQRGYRTEAGRAPLRETLAAALVLRSTWDESKPLLDPMCGSGTLLIEAALMACEMAPGVKREKWCFEALSDFDPEVWTEIRSEARVKSRRGVKKVDTHFYGFDRDYRVIQTARDNARRAGVEDLITFDVGDATKIERPEGFENGVVICNPPYGERLSTEPALIALYSEFGRQLKEQFGGCTASIYSSNDDLLACIRMRADKQFKLNNGALPCVQKNYSISESAERKEAANIEVAPEFMNRLKKNLSKLGKWARKEKLDCYRLYDADLPDYNAAIDVYKDYIIIQEYTAPKEISEDKARRRLTDMIRATVLVTGVETNNVILKVRQKQSGKNQYQKLAEKSRYFDVEEYGVKLIVNLQDYLDTGLFLDHKLTRKMIGDMAAGKDFLNLFAYTGSATVHAACGGAKSTMTIDMSRTYLEWAQKNMNTNDQTGTQHQFLQADCLQWLQQAEGEFDLIFIDPPTFSNSKRMDQTFDVQRDHIMLLENLKRMLRQDGTVVFSNNKRNFKMDEEALDKAGLQAKNISKQTLPLDFARNKHIHNCWIITHKED
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_BACHK
Sequence: MIFVLDVGNTNAVLGVFEEGELRQHWRMETDRHKTEDEYGMLVKQLLEHEGLSFEDVKGIIVSSVVPPIMFALERMCEKYFKIKPLVVGPGIKTGLNIKYENPREVGADRIVNAVAGIHLYGSPLIIVDFGTATTYCYINEEKHYMGGVITPGIMISAEALYSRAAKLPRIEITKPSSVVGKNTVSAMQSGILYGYVGQVEGIVKRMKEEAKQEPKVIATGGLAKLISEESNVIDVVDPFLTLKGLYMLYERNANLQHEKGE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_HAHCH
Sequence: MKKQIFFTLILLISGLARADLVIEIDKGSRAAIPVAVVPFANESGQPLAEDIGQIFTEDLKRSGDIEPLDRTKMVSIPSKAEEIYFRDWGLLGQRYLLVGGVQYDAPSQVYKVRYELYNVQSQQRVIGKIISGKSEKLRDMGHAIADAVYEAVTGIRGVFSTRIAYVTLEKSGAKNIYRLEVADADGRRSTELLKRSMPIISPAWSPDGKKLAYVSFESQRPAIYVQDVDTGTRTQVTSFKGLNSAPTWSPDGTKLAVTLSKDGNAELYVLDLRNNSLKRLTNHWAIDTEASWSPDGRTIAFTSDRGGGPQIYLVDASGGSPRRLTFEGRYNSRPRFSVDGKKVYYVHQRDGSFNVASLDLESGQDQILTQTEMDESPSVAPNGSMIIYATQKNGKGVLAVVGVNSGSKYTLPAQFGDVREPAWSPYISR
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HJE_SACS2
Sequence: MNRDIGKNAERELVSILRGEGFNAVRIPTSNSSPNPLPDIFATKGNTLLSIECKSTWENKVKVKEHQVRKLLDFLSMFTMKGVPLIAIKFKQVHEWRVLVPEKAEDIIVTIDNSIPIEDLFKILEKRIEEKILTP
What is the function of this protein?
A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination.  Acts only on 4-way DNA junctions in a sequence non-specific manner; introduces paired nicks in opposing strands 2 bases 3' of the point of strand exchange only on continuous strands of 4-way junction DNA.  Cleaves both mobile and immobile junctions.
What are the official names of this protein?
Holliday junction resolvase Hje, Hje.
What is the protein family that this protein belongs to?
Belongs to the Holliday junction resolvase Hjc family. Hje subfamily.
Protein: PIMT_XANOP
Sequence: MTPRLRLQPESVGIGMTSQRVRDRLVERLREAGIHDEATLNAMQTVPRHLFIDEALASRAYEDTALPIGHGQTISQPWVVARMTEAVLQVTPTKVLEVGTGSGYQGAILAALGLEVYTVERIGDLLRQARKRFRHLGMNVRSKHDDGRIGWHEHGPYDAIVVTAAAPALVDALVDQLAVGGRLVAPVGGASSQSLVQLTRGADGTIEQQVLAPVTFVPLLSGMLD
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_CHLCH
Sequence: MRLAGVNLPLNKHAVIALTHVYGIGRTSAENILRKAGIAYDKKISELSDEEAHAIREIIAEEYKVEGQARGEQQTAIKRLMDIGCYRGLRHRRSLPVRGQRTRTNARTRKGKRKTVAGKKKAVKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RS18_PHOLL
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MIAB_FINM2
Sequence: MEENNDKLATNSYVNLFINRHEHAPTYSIITHGCQMNEHDSEKIKTLLENMGFEKSDEKLDADFIIFNTCLVRENAEMKVYGQLGALKNLKRENPDMLIAVCGCMMQTGPARDIIREKYPQVDIVFGVNNINSLPYLIDRHLSSGKLVVDIERKDDIDEDITIKRDNEYVGYVNIMTGCNNFCTYCIVPYARGREQSRSVESILSEVKRMVDQGYKDITLLGQNVNSYGKTLENPVTFTELLTKVNDVEGLERLRFLTSHPKDISDELIEAMGKLDKVCENIHLPFQAGSNSVLERMHRRYTKESYLEKVEKLKKSVKGITFSTDIIVGFPGETEEDFQDTLDVVRKVGYEQAFTFKYNRRPGTKADLFEDQVDEDVKQDRLERLLDVAYPIFYEKNKSYLGTIQEVLIEGESKNNPEVMTGRTRTFKLVNVKCDKSYIGKLVNTKIVDFNSFALTGEMVD
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HV205_HUMAN
Sequence: MDTLCSTLLLLTIPSWVLSQITLKESGPTLVKPTQTLTLTCTFSGFSLSTSGVGVGWIRQPPGKALEWLALIYWDDDKRYSPSLKSRLTITKDTSKNQVVLTMTNMDPVDTATYYCAHR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 2-5, Ig heavy chain V-II region HE, Ig heavy chain V-II region MCE.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: ASNA_SALTI
Sequence: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAEVHKQFGLAPFLPDQIHFVHSQELLARFPDLDAKGRERAIAKELGAVFLVGIGGKLSDGRRHDVRAPDYDDWSSASELGYAGLNGDILVWNPVLEDAFELSSMGIRVDADTLMRQLALTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAQVRESIPAIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_CLOB8
Sequence: MRTKVTLACTECKQRNYDSMKNKKNDPDRLEMKKYCKFCKKHTLHRETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: CH60_BUCRM
Sequence: MAAKDEKFGNEARIKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPSITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATLLAQSIVNEGLKAVAAGMNPMDLKRGIDKAVISAVEELKNLSVPCSDSKAITQVGTISANADEKVGALIAEAMEKVGNDGVITVEEGTGLQNELEVVKGMQFDRGYLSPYFINKPETGVVELENPYILMADKKISNVREMLPILESVAKSGKPLLIISEDLEGEALATLVVNSMRGIVKVAAVKAPGFGDRRKAMLQDISVLTGGSVISEELAMDLEKSTLEDLGQAKRVVINKDTTTIIGGVGEKQAIQSRISQIRQEIQEATSDYDKEKLNERLAKLSGGVAVLKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRVAGKISNLRGHNEDQNVGIRVALRAMEAPLRQIVSNSGEEPSVVTNNVKDGKGNYGYNAATDEYGDMIDFGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKEDKTSDASSSPAGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLAB1_PHOV8
Sequence: MKLLSVLSLSLVLSCTTLSAQKVYEISAFGLKANSSKNASPVLQKALAKIKAEYKEGEKVILRFPEGRYEFHEKGAAVREYYISNHDQTNPKKVGIALEDMKNLTLDGQGSEFVFHGRMLPVSLLRSENCLLKNFSIDFENPHIAQVKIVENDPQDGIVFEPAPWVDYRIAKDSIFEAYGEGWTMRHSWGIAFDGDTKHLVYNTSDIGCPTKGASEVAPRRIHAPGWKDARLVPGTVVAMRGWGRPTPGIFLSHDVNTTIENVKVHYAEGMGLLAQLCENITLEKFGVCLKGDADPRYFTTQADATHFSGCKGKIVSCNGLYEGMMDDAINVHGTYLKVVKRVDDRTLVGRYMHGQSWGFEWGCPGDEVQFIRSNTMELVGKQNKIISIRPYDKEQTEGAREFLITFQEPVDQVINEQSGFGIENLTWTPEVLFSGNVIRNNRARGSLFSTPRKTIVENNLFDHTSGAAILLCGDCNGWFETGACRHVIIRKNRFVNALTNLFQFTNAVISIYPEIPDLKGQQQYFHGGPEGGIVIEDNEFETFDAPILYAKSVDGLVFRNNTIKLNTEYKPFHPNRNRFWLERVTNVTIAE
What is the function of this protein?
Alpha-galactosidase.  Removes both branched alpha-1,3-linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures.
What are the official names of this protein?
Alpha-1,3-galactosidase B, Exo-alpha-galactosidase B1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 110 family. B subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DPO4_LACLS
Sequence: MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKGKPVVIARNPLQTGGRGVVSTCSYEARAFGIHSAMSAKEAYDLCPQAIFISGNYEKYTKVSKQVREIFKRYTDNIEAASIDEAYLDVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKFLAKIASDYEKPHGLTLIMPDEALEFLAKLPVEKFHGVGKATVPKLHALGFFTGGDLQKADPVDLAEKFGIYGWELFQKANGIHNSKVKNHRERKSVGKERTYGKLLYLPDDIKAELIKISKQVSESLKRHQLKGNIIILKLRYSDFTTLTKRKSMVENLDSPEDIAEAAQQIFEEIDYDESLGVRLLGVTVSGFGVQKATLDMQ
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOC_NEORI
Sequence: MPDINNDVVAANFSRASRSYDLVAKIQKECCYKLVAMIRERLPHFMPASVLDIGAGTGYLTKLLLSEFPNACYTMNDISYEMLSRAREMVGESVSTILGDMSKVKFPVSDLIVSSMAIHWSSNPITVLKRVCRLSKVFAFSILVQPSLYEWNRLFHELSLPSPGLHYISSEEVELAMLDTSPTLFTWEVCNFDMRFASPKEFIRYMRQLGSNYSPAGFNAYHVRKVLKHAPGEFFSKYSVMFGVVSRSHF
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: TF2B_METST
Sequence: MKEDVAEMEKKETKCPECGSTKLINDHERGEVVCGACGLVIDDNIVDMGPEWRAFDHEQRDKRTRVGAPITYTIHDKGLSTMIDWRNKDIYGRDIPARNRAQWYRLRKWQRKIRISGATERNLAFALSELDRDSSRLGLPRSVRESASVVYRNAVENKLIRGRSIEGVVAASLYAACRRCKVPRTLDEIADVSRVSKKEVGRTYRFLTRELHIRLPPTSPIDYVPRFASELNLSGVVQSKAIEIINQAMDNGLTSGRGPTGVAAAALYIASVLLGERKTQRDVADIAGVTEVTIRNRYKELTEQLDMGVNL
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.