PharMolix/UniProtQA huggingface dataset:
Protein: RL14_HYPBU
Sequence: MPKGAAGAGPRRHIAAGLQVGSYVKVADNSGAKEAMIIGVIGYKGRLRRIPPAAVGDMVVVTVKKGTPEMRKQVVRAIVIRQRRPYRRPDGTWIAFEDNAVVIVSPDGTPKGSEIRGPVAREAAERWPKVANIASIII
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ATPB_IPOQU
Sequence: MRINPTTSGSEVSAVEKKNLGRIVKIIGPVLDVAFPPGKMPNIYNALVVQGRDNEQTNVTCEVQQLLGNNRVRAVAMSDTDGLMRGMEVIDTGAPISVPVGGSTLGRIFNVLGQPVDNLGPVDTNTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYLEMKESGVINEENIPESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLKT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GLYR1_MOUSE
Sequence: MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHTSADDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVTSGSADRGSKCLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTATEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH
What is the function of this protein?
Cytokine-like nuclear factor with chromatin gene reader activity involved in chromatin modification and regulation of gene expression (PubMed:29759984).  Acts as a nucleosome-destabilizing factor that is recruited to genes during transcriptional activation.  Recognizes and binds histone H3 without a preference for specific epigenetic markers and also binds DNA.  Interacts with KDM1B and promotes its histone demethylase activity by facilitating the capture of H3 tails, they form a multifunctional enzyme complex that modifies transcribed chromatin and facilitates Pol II transcription through nucleosomes.  Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300 (By similarity).  With GATA4, co-binds a defined set of heart development genes and coregulates their expression during cardiomyocyte differentiation (PubMed:35182466).  Regulates p38 MAP kinase activity by mediating stress activation of MAPK14/p38alpha and specifically regulating MAPK14 signaling.  Indirectly promotes phosphorylation of MAPK14 and activation of ATF2.  The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (By similarity).
What are the official names of this protein?
Cytokine-like nuclear factor N-PAC, NPAC, Glyoxylate reductase 1 homolog, Nuclear protein NP60, Putative oxidoreductase GLYR1.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. NP60 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Found in actively RNAPolII-transcribed gene bodies.
Protein: ANMK_BURVG
Sequence: MPQRHPQPAHPADGVYFGLMSGTSMDGVDGVAVRFETGRAPVVLAEAFVGFAQSLRDALFALQQPGDDEIDRESVAANALVARYAVCCHELQRTAGLSRDDVRAIGVHGQTVRHRPERGYTRQLNNPALLAELTHVDVIADFRMRDVAAGGHGAPLAPAFHATVFGAPGDTRVVCNLGGISNITILPAEGSDVRGFDCGPANALIDAWATRQLGKPYDDGGKFAARGTVHAALLDALLDEPYFTAPPPKSTGRDLFSAAWLDAKLAGFAQVAPEDVQATLTALTAVSVAREIARHAAGCKAVFVCGGGARNPVLLDALRRALQEAGVLATVDTTAALGVPPQQVEALAFAWLAYRFTARLPGNLASVTGAAGERVLGALYPR
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: DDL_VIBVY
Sequence: MMRNVLLLCGGGSSEHEISLLSSEYLQQQLGLIENVNVLKVEIKNEGWFDQKERLVYLDIHTKSVKSDEFNESIDIDFIVPCIHGFPGETGDIQSLFELAGIPYLGCGPEASSNSFNKITSKLWYDAIGIPNTPYLFLTENNEESHQLSREAFDKWGKLFVKAARQGSSVGCYSVTNIEQLSDAIDKAFGFSHQVLVEKAVKPRELEVSAYEMNGQLHISKPGEIIAPDGAFYSYDEKYSAGSHSITEVEAKNLTEQQLATIQLCSEKVFRQMNLRHLSRIDFFLTSEGEIYLNEVNTFPGMTKISMFPKMLQHNGHKFHEFLADCIERSL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_DECAR
Sequence: MKFSESWLRTLVDPKLSSEELSHLLTMAGLEVEELDPVAPAFDNVVVAHVLDVVKHPDADRLNVCQVDTGSGAPTTIVCGAPNVAVGLKVPCALPGAKLPGDFTIKIAKVRGIESSGMLCSAKELGIAEEASGLLVLPSDAPVGQAIRQYLDLDDNLFELKLTPNRADCLSLLGIAREVGAITGAATSLPVVPEVVASIADSRAVVLDAPEACPLYCGRVLKGVNAKAPTPEWMKRRLERSGIRAISALVDVTNYVMLELGQPLHAFDNTRLEGAVHARLAKPEEKLLLLNEQTIAVDADVLVIADDVKPLAMAGIMGGEESGITLETSELFLESAFFAPKAIAGRARRYGFGSDASHRFERGVDFGGARRAIERATQLILEICGGQAGPVVEAKAVLPVRKPVLLRTARAEMVLGLPLGAERIAGLFAGLDLSFVCEGDNFQVTPPSWRFDMEVEEDLIEEIARLYGYDNIPSVSPRGALKMQVQPEARRPAYRLRQMLADRGYQEVVNFAFVEAAWEADFAENVAEAELIRLANPIASQMAVMRSTLFGGLISNLITNLKRKQTRVRLFEVGRTFHRAADAVPVNGFHQPWKLAGLAFGGALPEGWGSGARKVDFYDVKGDIEALLAPAVLRFEKLAHPALHPGRAARILFDGRDIGCIGEVHPEWVQKYDLPQAPVVFELDFDAVKAANVPAYAEVSKFPPVIRDLAIVVDQNVVLQTLLDGLKGQVSDLIQDIQLFDVYVGKGVPENKKSLAFRIVMQDTQRTLQDSEVDAAMQQLVSCFEQAFGAQLRA
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATP_ECO57
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVLLSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQRLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COF_ESCF3
Sequence: MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHVLEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLDRVTKICFCGDHDDLTRLQIQLHEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDNPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: C99A3_ORYSJ
Sequence: MMEINSEATVTLVSVVTLPILLALLTRKSSSKKRRPPGPWNLPLVGGLLHLLRSQPQVALRDLAGKYGPVMFLRTGQVDTVVISSPAAAQEVLRDKDVTFASRPSLLVSEIFCYGNLDIGFAPYGAYWRMLRKLCTVELLSTKMVRQLAPIRDGETLALVRNIEAAAGGKKPFTLATLLISCTNTFTAKAAFGQACGGELQEQFLTALDEALKFSNGFCFGDLFPSLRFIDAMTGLRSRLERLRLQLDTVFDKIVAQCESNPGDSLVNVLLRIKDQGELDFPFSSTHVKAIILDMFTGGTETTSSTTEWLMSELMRNPEVMAKVQAEVRGVFDNKSPQDHEGLLENLSYMKLVIKETLRLNPVLPLLLPHLCRETCEIGGYEIVEGTRVLINSWAMARSPEYWDDAEKFIPERFEDGTADFKGSRFEYLPFGTGRRRCPGDIFAMATLELIVARLLYYFDWSLPDGMQPGDIDMELVVGATARRKNHLQLVASPYKPISMQS
What is the function of this protein?
Involved in momilactone phytoalexins biosynthesis; acts as a multifunctional diterpene oxidase.  Participates in the biosynthetic steps between 9-beta-pimara-7,15-diene and 3-beta-hydroxy-9-beta-pimara-7,15-dien-19,6-beta-olide.  Catalyzes also consecutive oxidations at C19 of syn-stemod-13(17)-ene.
What are the official names of this protein?
9-beta-pimara-7,15-diene oxidase, Cytochrome P450 99A3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CCNB3_CANLF
Sequence: MPLPLPSRSSKPETKKSRSSKIVPSGNNGQSEKRGENYQEKISSSSPRRLCKKRSAFEDLTNASQSQPAQLKKEANKEFVKDVPKKIKGNTPALGLAKSNEVNMVSYKLESSPGVVSTTLVPNITEKPLILERSTTSGTITTEEASFFRKPLILKEESTTEDTGLIKRSLFLKKFTNKGEISLMEKPTSVQEEADSNDEFVVKLITFGKKHKTEEVAITKGTLSLKKMCTYQEDLALQDITVEENSFFMEPTNFRKKPKTDDVTPTKKMLSLKKKKYITLGKVSRMKKPLVLQKTNSEDESPLIKEPLAFKKKPTKKETTFTLRPLSLKKYTTQGKMAHLKKPLESQNTSGEKALIKEPLSFKKKPITKEESLFQEFSASQEKHTTDREVVLLKKPQVLQEEKDSKDKFLMEPMFLRKKCTTKETNPTKKPLPIKKKCTIQGKMYYLKKPLVLQKTTPGEESFVKEPLSFKKNTTELSMLQEKYTTQEEVSVLKKALTLQKTLTEEESHLKEPLAFKKKHTTEEATPTKKLSSLKRKRFTAQGKRSCLMKPLVLQTSSGEKTHIKEPLSFKKRSAIEESFFKESPVLQEKHTMQGEVALLEKPGALQENVSSEDEFLMEPISFRKTHTTNEVVSTKEPLSLKKKKCTTQITMSICQELLDLQNIISKDKASFFMEPVSLREKSLAEEVILTKTPLSLKKKEITQGKIFLLKKPLVSEKTTSEEESLFKKLLPFNKKSTTEGEFLFQDPSVLQEKHTTPQEVSLSTKPLTLPEKTTTEEEPYIKEPLTLEERPTTKEEFLSQEPFSLHAKPTNEDESLFWKALGLQKTQTKEDSLKKLLTLQEKNTTDEESLLNKPSILKEELSTKVATSIEKELSLKKKPTAQGEVFLLKKQLALQENITNEESLIKQPLAFLKPSIEEAILRESLALQEKPRSEEETLFKEPLSFQEKPTLNEAFHFKEIISLNEKHSTGKELSLKEPLALQENPTQKEDTSLEDSLILQVETSSRVPSTPPESRAGMSSVGKLSTTSKSSVCESSSNKPSSSWGESSQKEMTPLEDIDRNHGDPFFNSIYAKDIFSYMKEREEKFILKEYMNKQTDISSCMRAILVDWLVEVQMTFEMSHETLYLAVKLVDHYLMEVICKRDKLQLLGSTAFLIAAKFEEPCPPCVDDFLYICDDIYQRHEMLSMEISILQTLKFDINIPIAYHFLRRYARCLHASMKTLTLSRFICEMTLQEYDYVQERASKLAAGSFLLALYMMKLRYWVPALEYYSGYKTSDLHPLVKQLNILLTLRPSNKLKTVYSKYSHQVFFEATKIPPLDMLKLEEILNYC
What is the function of this protein?
Cyclins are positive regulatory subunits of the cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division.  Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity).
What are the official names of this protein?
G2/mitotic-specific cyclin-B3.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NITR2_BRADU
Sequence: MMDSNRPNTYKAAVVQAASDPTSSLVSAQKAAALIEKAAGAGARLVVFPEAFIGGYPKGNSFGAPVGMRKPEGREAFRLYWEAAIDLDGVEVETIAAAAAATGAFTVIGCIEREQGTLYCTALFFDGARGLVGKHRKLMPTAGERLIWGFGDGSTMPVFETSLGNIGAVICWENYMPMLRMHMYSQGISIYCAPTADDRDTWLPTMQHIALEGRCFVLTACQHLKRGAFPADYECALGADPETVLMRGGSAIVNPLGKVLAGPCFEGETILYADIALDEVTRGKFDFDAAGHYSRPDVFQLVVDDRPKRAVSTVSAVRARN
What is the function of this protein?
Nitrilase that acts on various kinds of nitrile compounds such as aliphatic and aromatic nitriles.  Has higher activity toward aliphatic nitriles compared to aromatic nitriles.  Among the different substrates tested, has the highest activity toward hydrocinnamonitrile.
What are the official names of this protein?
Nitrilase blr3397.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: OPDC_PENO1
Sequence: MGDLPTSQQALKVASSGRVILETGHPLPELGADEVLVRVACVALNPYDAKSVDMSPSPGATAGLDFAGEIVALGEAVNSSTRLAVGKRVCGFVFGNNPDRRDNGAFAEYVAVPASLVLCIPDSMTFLEAATLPCGLATTGTALYNSHNLGLPLLRPGSEVNSSNKSSTYVLVYGGGTATATIIIQVLRRSGFIPITTSSPHNFNRLQQLGAEATFDYHSPTCGSDLRDYTHNRLAFAIDCISSTDSMQICYEAIGTAGGRYVSLDPFPLNKHTRRSIRPVWLFSFTIFGSAIKWDTPYNFPARPDDRESAERWYAEIEAILATGELVTHPFQEETGGLSSVIDGIGAVRNGQITGYKLVYPIRNCAY
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of oxopyrrolidines, polyketide-amino acid hybrid compounds with feature structures of tetramic acid (PubMed:36005526).  The polyketide chain is first assembled by the highly reducing PKS module of opdA using acetyl-CoA as the starter unit and five malonyl-CoA as the extender units (PubMed:36005526).  OpdC acts as trans-acting enoyl reductase and reduces the terminal alkenyl to alkane (PubMed:36005526).  The 17R in oxopyrrolidine A and 15R, 17S in oxopyrrolidine B are generated by non-stereospecific catalysis of the ketoreductase (KR) domain and enoyl reductases (PubMed:36005526).  Then the polyketides with specific configurations are transferred to the NRPS module of opdA and linked to L-tyrosine to form an amide bond (PubMed:36005526).  Finally, the oxopyrrolidines are offloaded through a Dieckmann cyclization catalyzed by the terminal D domain to give a tetramic acid moiety (PubMed:36005526).
What are the official names of this protein?
Trans-enoyl reductase opdC, Oxopyrrolidines biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RPPH_SHIDS
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQENTPKPQNASAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: Y3630_MYCTU
Sequence: MAVGAAAVTEVGDTASPVGSSGASGGAIASGSVARVGTAAAVTALCGYAVIYLAARNLAPNGFSVFGVFWGAFGLVTGAANGLLQETTREVRSLGYLDVSADGRRTHPLRVSGMVGLGSLVVIAGSSPLWSGRVFAEARWLSVALLSIGLAGFCLHATLLGMLAGTNRWTQYGALMVADAVIRVVVAAATFVIGWQLVGFIWATVAGSVAWLIMLMTSPPTRAAARLMTPGATATFLRGAAHSIIAAGASAILVMGFPVLLKLTSNELGAQGGVVILAVTLTRAPLLVPLTAMQGNLIAHFVDERTERIRALIAPAALIGGVGAVGMLAAGVVGPWIMRVAFGSEYQSSSALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYSLGWVGATVGSGLLLLLPLSLETRTVVALLCGPLVGIGVHLVALARTDE
What are the official names of this protein?
Uncharacterized protein Rv3630.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1510 and M.bovis Mb3654.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU4LM_ORYAF
Sequence: MPPIYMNIILAFTLSLMGMLVYRSHLMSSLLCLEGMMLSLFILGTTMALNMHFTLMTMLPIVLLVFAACEAAVGLSLLVMVSNTYGLDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ISPF_LISMO
Sequence: MIRIGQGYDVHKLAYDRDLIIGGVKIPYEKGLLGHSDADVLLHAITDAIIGAIGAGDIGHFFPDTDMVFKDADSAELLAEIWQKVEADGFRLGNLDATIIAEKPKMAPYVEQMKLRIAELLHADSAQVNVKATTTEKLGFTGREEGIASLAVVLLEK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ATPF_PARD8
Sequence: MSLLTPDSGLLFWMIVSFGIVFVILSKYGFPVIVKAIEQRKAYIDNSLETARQANERLAHIQAEGEKMLAEAKEKQNAVLKEAFAEKERIIEEARKKAVSEAHLQIEEATRRIREEKEKAIREVRSEIADLSIAIAEKVMKEKIGRDKEQQQMIDRLLDEVSFSKS
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: QUEA_ANADF
Sequence: MRLSDFDYELPEELVAQEPVTPRDASRLLVLPREGAAEHRAFTDLPDLLAPGDLLVFNDTKVIPARLVGTKPTGGKVELLLCEPLGGGLGSRWRAMGQASKPIREGTTLLFEGLEARVEASEGEGFYVVTLDREGEALEAALARAGRIPLPPYIRRAPSDVDRERYQTIWARAPGSAAAPTAGLHFTEAILARLAARGVERTAVTLHVGPGTFLPVRGDSVEGHRMHAEQYEVRPEAAAAIAACRARGSRVVAVGTTSVRTLESAWRGGAVAAGAGRTALFVRPGHAFRAVDALVTNFHLPRSTLLMLVCAFGGTHRVLAAYRDAVARRYRFFSYGDAMLLARAD
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLPA_METKA
Sequence: MVEIEIEPHEEFEGVYWAIFEDGRKKPATENLVPGHQVYGERLVEYDGKEYRVWEPRRSKLAAMIMNGMEYFPFEEGSKVLYLGAAAGTTPSHVSDIIKESGVEYCVEFASRMMQELIPVCEKRPNMIPILGDATKPHGYAPLVEQVDVIYQDIAQPKQAEVVADNAEAFLRPGGYVIVAIKARSIDVTKEPEEVFEDEERKLEERGFEVLEVIDLEPYERDHVGIVAEYHG
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: LI601_CANLF
Sequence: MKLLLLCLGLILVHAHEEENDVVKGNFDISKISGDWYSILLASDIKEKIEENGSMRVFVKDIEVLSNSSLIFTMHTKVNGKCTKISLICNKTEKDGEYDVVHDGYNLFRIIETAYEDYIIFHLNNVNQEQEFQLMELYGRKPDVSPKVKEKFVRYCQGMEIPKENILDLTQVDRCLQARQSEAAQVSSAE
What are the official names of this protein?
Lipocalin Can f 6.0101, Allergen Can f 6.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHM1B_HUMAN
Sequence: MSNMEKHLFNLKFAAKELSRSAKKCDKEEKAEKAKIKKAIQKGNMEVARIHAENAIRQKNQAVNFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLKTMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGSVGTSVASAEQDELSQRLARLRDQV
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes.  ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.  The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).  ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.  Involved in cytokinesis.  Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells.  Involved in HIV-1 p6- and p9-dependent virus release.
What are the official names of this protein?
Charged multivesicular body protein 1b, CHMP1.5, Chromatin-modifying protein 1b, CHMP1b, Vacuolar protein sorting-associated protein 46-2, Vps46-2, hVps46-2.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome. Late endosome membrane; Peripheral membrane protein. Note=Localizes to the midbody of dividing cells, colocalizing with CEP55 and CHMP5. Localized at the periphery of the Fleming body.
Protein: EX7S_THEPX
Sequence: MNEELTFEEEMMRLEEIVNTLEKGNLMLEESFNLFKEGVEISKRLEKRLSEVEGKITLLINENEEIDFKEEEKDV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_PSEPG
Sequence: MYTLARQLLFKLSPETSHDLSLDLIGAGGRLGLNGMLCKQPAALPVSVMGLNFANPVGLAAGLDKNGAAIDGFAQLGFGFVEIGTVTPRPQPGNPKPRLFRLPEATAIINRMGFNNLGVDHLLERVRAARYNGVLGINIGKNFDTPVERAVDDYLICLDKVYTAASYITVNVSSPNTPGLRSLQFGDSLKQLLDALAERREQLAVTHGKRVPLAIKIAPDMSDEETALVAAALMASGMDAVIATNTTLGREGVEALPHGGEAGGLSGAPVLAKSTHIVKVLAGELGGKLPIIAAGGITEGRHAAEKIAAGASLVQIYSGFIYKGPALIREAVDAIAAMPRV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RCF1_MAGO7
Sequence: MPTTGPPPPLPGDRPLPSSFDNDEDFYNENGFQKIARKLKQEPLVPLGCVLTVAAFTGAYRAMRAGDHGRVNRMFRYRIAAQGFTILAMVAGGIYYSDDRHKEREMWKAKRDADEEEKRLKWIKELEARDEEDKLAKEIMDKRRQRAAAAAAKREGRAVEDKAAEGGAAAAQDAKSSSGLSWASAPGWFGGNKNEPDANAQTNTGDAEKPSEK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: LYSC_HUMAN
Sequence: MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.