PharMolix/UniProtQA huggingface dataset:
Protein: FBIA_MYCBT
Sequence: MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPVDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA
What is the function of this protein?
Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
What are the official names of this protein?
Phosphoenolpyruvate transferase, EPPG:FO PEP transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: PTH_LISMF
Sequence: MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMTSEIIVGGEKMILVKPLTFMNASGECIRPLMDYYNIPIEDVVIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHVKTQEFNRIRVGVSRPLKGEVIHYVLGDFPKAEQPDIIAAIQKSADAIEDFAQTPFIEVMNKYNQK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALF_SINMW
Sequence: MARITLRQLLDHAAERSYGVPAFNINNMEQGLAIMEAARACDAPVILQVSRGARSYANDIMLAKMMEALEVMYPDIPLCIHQDHGNNVATCLTAIQHGFTSVMMDGSLKEDAKTPADYAYNAMITTEVSRLAHMVGASVEGELGCLGSLETGHGEAEDGHGFEGALDRSQLLTDPDEAARFVAETGVDALAVAIGTSHGAYKFTRKPTGEVLAMDVIEKIHERLPDTHIVMHGSSSVPQEWQDVFNAHGGEMRETYGVPVEEIVRGIRFGVRKVNIDTDLRLAAAAAFRRVADTSRTEFDPRKFLKPAMDAMSAVCKARFEAFGTAGNASRIKVVPMAEMARRYASGSLKPQAKRAEAA
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: ORT1_YEAST
Sequence: MEDSKKKGLIEGAILDIINGSIAGACGKVIEFPFDTVKVRLQTQASNVFPTTWSCIKFTYQNEGIARGFFQGIASPLVGACLENATLFVSYNQCSKFLEKHTNVSPLGQILISGGVAGSCASLVLTPVELVKCKLQVANLQVASAKTKHTKVLPTIKAIITERGLAGLWQGQSGTFIRESFGGVAWFATYEIVKKSLKDRHSLDDPKRDESKIWELLISGGSAGLAFNASIFPADTVKSVMQTEHISLTNAVKKIFGKFGLKGFYRGLGITLFRAVPANAAVFYIFETLSAL
What is the function of this protein?
Required for arginine biosynthesis.  Transports ornithine synthesized from glutamate in the mitochondrial matrix to the cytosol, where it is converted to arginine.
What are the official names of this protein?
Mitochondrial ornithine transporter 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS7_BRADU
Sequence: MSRRHSAEKREVLPDPKFGNIVITKFMNSVMYAGKKSVAEGIVYGALGIIETKTKQNPLGVFEQALENVMPTIEVRSRRVGGATYQVPVEVRSTRRQALGIRWLISAARERNEKTMTERLSAELLDASNNRGNAVKKREDVHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL36_LACP3
Sequence: MKVRPSVKKMCEHCKVVRRKGRVMIICSANPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RL35_ICTPU
Sequence: MAKIKARDLRGKKKEELLKHVDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPRKTRAIRRQLTKHEQGLMTKKMQRRSRLYSMRKFAVKA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3675_HALWD
Sequence: MNDYHYVYIVECSDESLYTGYTTDVERRVREHNAGEGAKYTRGRTPVQLVHFECFDTRSAALSREHEIKSYTREKKQQLAEEGTDINQP
What are the official names of this protein?
UPF0213 protein HQ_3675A.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: AROC_LISW6
Sequence: MRYLTAGESHGPGLTTIIEGLPAGMPLLAEDVNKELKRRQGGHGRGARMRIEKDQVQITAGIRHGKTLGAPVAMFVENKDWKHWETVMSIEPVPEKNEKSRRVSRPRPGHADLVGGMKYGHNDMRNVLERSSARETTVRVAAGAIAKKLLHELGIEVAGHVLEIGGTRANLTRDFSVSEIKETSEASPVRCLDEVAEKEMMQKIDDAKKNGDTIGGIVEVVVGGVPAGLGSYVQWDKKLDAKIARAIVSINAFKGAEFGVGFEAARKPGSEVMDEILWSKEDGYTRRTNNLGGFEGGMTNGMPIVVRGVMKPIPTLYKPLQSVDIDSKETFNASVERSDSCAVPAASVVAEAVVAWEVAVAVLEKFDGDRFDTLKKHVEEHRNLTKEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CFA68_BOVIN
Sequence: MTATDYHCYSEFFQRQVLACFLTNPHYGSLINADGHAEVWTDWNDMSKFFQYGWRCNTNEDAYSNRTLMGNWNQERYDLKNIVQPKPLPSQFGHYFETTYDTSYNNRRPLSTHRFKREPHWFPGHQPELVPPPYKCTEKSTYMTSYSKPQTDHHSVCVWNPSNCQFQSP
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Cilia- and flagella-associated protein 68.
What is the protein family that this protein belongs to?
Belongs to the CFAP68 family.
Protein: ISPH_ACIBS
Sequence: MEIVLANPRGFCAGVDRAIAIVNRALECFNPPIYVRHEVVHNKFVVDDLRQRGAVFVDELDQVPDDSIVIFSAHGVSKAVQQEAERRGLKVFDATCPLVTKVHIEVTKYAREGTEAILIGHEGHPEVEGTMGQYDKLKGGDIYLVEDEADVAALEVRHPEKLAFVTQTTLSIDDTAKVIDALRAKFPNIQGPRKDDICYATQNRQDAVRDLAEKCDVVLVVGSPNSSNSNRLRELAERMGKAAYLVDNADQLEQSWFNDTCKIGVTAGASAPEILIKQVIQRLQDWGAQAPKELEGREENITFSLPKELRIHVTQA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: ENO_CAMJ8
Sequence: MLVIEDVRAYEVLDSRGNPTVKAEVTLSDGSVGAAIVPSGASTGSKEALELRDNDERFGGKGVLKAVANVNETIADEILGLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATARAAAAALGMPLYRYLGGANASILPVPMCNIINGGAHANNNVDFQEFMIMPFGFTSFKEALRSVCEIYAILKKELANSGHSTALGDEGGFAPNLANNTEPIDLLMTCIKKAGYENRVKIALDVASTEFFKDGKYHMEGKAFSSEDLIERYVELCAKYPICSIEDGLAENDFEGWIKLTEKLGNKIQLVGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTVRLAQRNNYKCVMSHRSGESEDAFIADFAVALNTGQIKTGALARGERTAKYNRLLEIELESDEYLGEKL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ATPD_PELPB
Sequence: MSTLIASRRYASALLSAAEEGNFLNQIVDELHVIKEVLEHSRDLVYALRSPLVKGDRKIHILEEIFKDSVGEKMFLFLRLVAHKKRAGLLPEIIDEFQILLDEKRGVINVDITSATALSDEQTAELVTKLAAFTGKEIRPRMAINEQFIGGVAVKIGDTIYDGSISHQLQMLRKSLVS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYI_NITOC
Sequence: MAKYKETLNLPKTAFPMKANLAQREPQALKRWQAMDLYGKLRNAARGRPRFILHDGPPYANGAIHIGHAVNKILKDIIVKSKSLSGFDAPYVPGWDCHGLPIELNVEKKVGKPGRKIDVASFRRACRDYARKQVNAQREDFERLGVLGDWCHPYLTMDYQFEADVIRTLGKIIEKGHLHKGVKPVHWCVDCGSALAEAEVEYQEKTSPAIDVRFPVVEEVELLARCKAEIPGAGPMSVVIWTTTPWTLPANQAVALHPALKYVLVECSAGQGRERLLLAEGLYREVLARYSAESAVILATCQGDELEGLKLQHPFYERTVPIILGEHVNLEAGTGAVHTAPGHGQDDYVVGNRYQLSIDNPVGGNGCFLPETPLFAGEPVFKANDHIIQVLKERGNLLREQSLQHSYPHCWRHKTPIIFRATPQWFINMEREGLRTAALAEIKKTRWLPGWGQQRIEGMVENRPDWCISRQRAWGTPIPLFVHCQTGELHPDTPRLMEEVARRVEEKGIEAWFELEPKELLGNQAPAYEKVGDTLDVWFDSGVTHTCVLETREELGVPADLYLEGSDQHRGWFQSSLLTSVAIRGTAPYRMVLTHGFTVDAKGKKMSKSQGNVVAPQQVMGSLGADILRLWVAATDYRGEMNVSDEILKRIADSYRRMRNTARYLLANLNGFDPTIHGVPAKDMLALDRWALDRASLLQGEIVQAYEDYNFHLIYQRVHNFCAVDMGAIYLDIIKDRQYTTQADSRARRSAQTAMYHIAEALVRWLAPVLSFTADEIWQYLPGERGESVFLTTWYEDLPSLGEEAPWGRAFWDVILAAREAIAKVLEGVRVEGRIGSSLDAEVDLYVEESLYQALRKLGDELRFVLITSYARVYPAQKRPVEALETEMPGLWTVVIPSHYPKCVRCWHHREEVGSHEDHPELCSRCVENTEGGGEQRAFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_SHIFL
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQVGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPTDRDFIGREALEVQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: Y1464_SYNY3
Sequence: MNTTFPAVYGPVNSWRYGRSLGIDPIGAISTCSFNCVYCQLGEIEHLSGDRQIFIPTADILRELAQFAPWEVDVITLSGSGEPTLAKNLGEILEGIKKLTGKLTLVLTNATLLNDAQVREELSLADKISVKLDGLWPDQLQRINRPIAGIELEQILTGIQTFQQEFTGELSVQTMVLQPWDQTTENRYLELLSLIKPTEVQLNRPTRPKPLQRELEGRGNHTGTPYGDRPVTQIKCVDGQTLQNLAKKISGAIGIPVRCAPVKVL
What are the official names of this protein?
UPF0026 protein slr1464.
What is the protein family that this protein belongs to?
Belongs to the UPF0026 family.
Protein: 7B2_HUMAN
Sequence: MVSRMVSTMLSGLLFWLASGWTPAFAYSPRTPDRVSEADIQRLLHGVMEQLGIARPRVEYPAHQAMNLVGPQSIEGGAHEGLQHLGPFGNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTADDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGLGKWNKKLLYEKMKGGERRKRRSVNPYLQGQRLDNVVAKKSVPHFSDEDKDPE
What is the function of this protein?
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway.  Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated.  Also required for cleavage of PCSK2 but does not appear to be involved in its folding.  Plays a role in regulating pituitary hormone secretion.  The C-terminal peptide inhibits PCSK2 in vitro.
What are the official names of this protein?
Neuroendocrine protein 7B2, Pituitary polypeptide, Secretogranin V, Secretogranin-5, Secretory granule endocrine protein I.
What is the protein family that this protein belongs to?
Belongs to the 7B2 family.
What are the subcellular locations of this protein?
Secreted. Note=Neuroendocrine and endocrine secretory granules.
Protein: FPG_RICAE
Sequence: MPELPEVETLKNSLKDKLIGLIIENVELKRDNLRYKLSPLLTTEILNTNILDVRRRAKYLIIDFNNDYSLIVHLGMSGRFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEKEFFNDLGIEPFSDLLTLEYLKDKLQTKKIPIKNLIMDNRVIVGIGNIYASESLHLARIHPDKSGNDLRDDEIENLIKAIRDVLTKAITAGGTTLKDFVNGDNKPGYFTKQLKVYGREGQSCLSCSSTIIKIKHSGRSTFYCKTCQYS
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SUS1_KLULA
Sequence: MKYFNGLFSIFFFLLLTNYLNFNSRISNQLNQMLLDDGWIDKVKQLTREEMERSDSTNFVDILNKVEPQALNMVNDKTRTEILQTIKEFLNDIVEV
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor SUS1.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, P-body.
Protein: ZN384_RAT
Sequence: MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISTPMIVSALPPGSQALQVVPDLSKKVASTLTEEGGGGGGGGGTVAPPKPPRGRKKKRMLESGLPEMNDPYVLAPGDDDDHQKDGKTYRCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQASQASQQQQQQQPPPPQPPHFQSPGAAPQGGGGGDSNQNPPPQCSFDLTPYKPAEHHKDICLTVTTSTIQVEHLASS
What is the function of this protein?
Transcription factor that binds the consensus DNA sequence [GC]AAAAA.  Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1.
What are the official names of this protein?
Zinc finger protein 384, Cas-associated zinc finger protein, Nuclear matrix transcription factor 4, Nuclear matrix protein 4.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: GLE2_CHATD
Sequence: MAGLFGTTTSTTTSTLGDLKNDVELGSPPEDSITDLSFNPNPNDPKDFLAVSSWDKKVRVYEIAANGQNQGKVQMEHEGPVFAVDFFKDGTKVISAGADKQAKVLDLASGQAMQVAAHDAPIRCVKYFEAGGTPMAVTGSWDKTIKYWDFRSATPAGTVQCQERVYTMDVKENLLVIGTADRYIDVINLKEPVKFYKTLQSPLKWQTRVVSCFTDSQGFAIGSIEGRCAIQYVEDKDQSMNFSFKCHRDTPQNNVTNVHAVNAISFHPQHGTFSTAGSDGTFHFWDKDAKHRLKGYPNVGGSITATKFNRNGTIFAYAISYDWSKGYQGNTANYPTKVMLHPVLGDECKPRPSVKKR
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  It is specifically important for nuclear mRNA export.
What are the official names of this protein?
mRNA export factor GLE2, Nuclear pore protein GLE2, Nucleoporin GLE2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat rae1 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Protein: UXAC_VIBVU
Sequence: MKNFLCEDFLLSNETARRLYHEHACHQPIYDYHCHLNPAEVAQNRQFDNLGQIWLEGDHYKWRGMRSAGIEERLITGDASDYDKYMAWAKTVPQTLGNPLYHWTHLELRRPFGITNTLFSPDTADQIWHQCNELLATPEFTARGIMQQMNVVMAGTTDDPIDSLKHHKTIAEDDTFNVKVLPSWRPDKAFKIELDLFADYMHKLGEVADIEIRRFDDLLSALDKRLAHFDAHGCRAADHGIEIVRYAPIPSEADLDVLLARRLNGEVLSELECAQFSTAVQVWLGKRYAQLGWVMQLHIGAQRNNSTRMFQLLGADAGFDSIGDRPFAFELAHLLDEMDQTNELPRTILYCLNPRDNEMMATMIGNFQGGGIAGKVQFGSGWWFNDQKDGMQRQMEQLSQLGLLSQFVGMLTDSRSFLSYTRHEYFRRILCDMVGRWAENGEVPNDLSLLGPMVEDICFGNAKRYFEERV
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: HIS1_THEVB
Sequence: MLTIALPKGALLKDSVAYFQRLGLNFEALLEPANRQLQVLSQDGRARALLVRAQDVPVYVQYGQAQLGIVGYDVLREKNPHVAKLADLGFGQCRLSVAVKASSPYRSARDLPPHCRVASKFVRCADAFFQQLDLPVDIVPLYGSVELGPITGMAEAIVDLVSTGRTLKENGLVEIEQIFSSTAYLIAHPRSYRLNLNGLGHYVPQLTGAIA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLVAP_MOUSE
Sequence: MGLSMDRSPYARTGDQQRGCWYYLRYFFLFVSLIQFLIILGLVLFMIYGNVHATTESSLRATEIRADSLYSQVVGLSASQANLSKQLNISLLVKETVMQQLLTTRREMERINASFRQCQGDLITYINYNRFIAAIILSEKQCQEQLKEVNKTCEALLFKLGEKVKTLEMEVAKEKAVCSKDKESLLAGKRQTEEQLEACGKARERQQQEQQVTEENLRKVQSLCIPLDQEKFQADVLSAWRDSLIYRTLETLPYHYQLMPEYASLRRTCESLPGIMTTKIEELARGLRAGIERVTRENAELRRQKLELERAAQAAQEARARAGTEAQARETQLRAECARQTQLALEEKAALRAQRDNLERELEARKRELEQLRTEVDVRISALDTCVKAKSLPAVPPRVSGPPPNPPPIDPASLEEFKKRILESQRLPVVNPAAQPSG
What is the function of this protein?
Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae.  It is also required for the formation of stomata of caveolae and transendothelial channels.  Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs.  Plays a specific role in embryonic development.
What are the official names of this protein?
Plasmalemma vesicle-associated protein, MECA-32 antigen, Plasmalemma vesicle protein 1, PV-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Membrane, caveola; Single-pass type II membrane protein. Cytoplasm, perinuclear region. Note=Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region.
Protein: DAPF_CAMJE
Sequence: MKFYKYCASGNDFVITNADRKEDRSALAKELCNRYEGIGADGFIVILPHEKYDFEWEFYNNDGSRAAMCGNGSRAAAHFAHHINKINPNMSFLTGAGIIKAKVNQDKVEVSLGKIKSVQNTFEELGKTWQLCNTGVPHLVHFCQNLDEFDTMLCQKMRQKYNANVNFVKILDENHLKVRTYERGVEDETLACGTGMGACFYLAFLNKKVQNKVKITPKSGEEVGFAYKNEELFFEGKVKYCFEANYNFF
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_STAAN
Sequence: METIFDYNQIKQIIPHRQPFLLIDKVVEYEEGQRCVAIKQVSGNEPFFQGHFPEYAVMPGVLITEALAQTGAVAILNSEENKGKIALFAGIDKCRFKRQVVPGDTLTLEVEITKIKGPIGKGNAKATVDGQLACSCELTFAIQDVK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_FRATW
Sequence: MINDILKDAENRMKKSLEVLADDLAKIRTGRAHPDLLAHVTIDYYGVETPITQAANITVLDARTLGITPWEKGLSSKIEKAILTSDLGLNPTNLGDSLRVPMPALNEERRKELVKLVKSETEAGRVSIRNIRRDANGDIKELLKEKEITEDQAKKAEDDIQKITDKMIAQADALAAKKEQDLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_EUCGG
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAMKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.