PharMolix/UniProtQA huggingface dataset:
Protein: QUEA_BACVZ
Sequence: MKVDLFDFELPERLIAQVPLKERDASRLMVLDKQTGGLTDSSFKEIVSFFNEGDCLVLNNTRVLPARLFGTKEDTGAKVELLLLKQEENDTWETLVKPAKRVKKGTVLTFGDGRLTAVCTEELDHGGRKIEFRYDGIFYEVLESLGEMPLPPYIKEQLDDKERYQTVFSKEIGSAAAPTAGLHFTEEILDELKQKGVRIEFITLHVGLGTFRPVSADDVEEHNMHAEFYEMTEETAASLNEVRKAGGRIVSVGTTSTRTLETIAGEHDGEFTASSGWTSIFIYPGYEFKAIDGMITNFHLPKSSLIMLVSALAGREHVLSAYRHAVEEEYRFFSFGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_SHEPW
Sequence: MIALIQRVSEANVVVDGETIGEIDKGLLVLLGVEREDDLAKMEKLATKVMSYRVFSDDNGKMNLNLEQAGGSLLVVSQFTLAADTGRGLRPSFSGAGTPEQARELYQAFVDFCLSKGVNTQTGEFAADMKVSLVNDGPVTFNLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NR13_COTJA
Sequence: MPGSLKEETALLLEDYFQHRAGGAALPPSATAAELRRAAAELERRERPFFRSCAPLARAEPREAAALLRKVAAQLETDGGLNWGRLLALVVFAGTLAAALAESACEEGPSRLAAALTAYLAEEQGEWMEEHGGWDGFCRFFGRHGSQPADQNSTLSNAIMAAAGFGIAGLAFLLVVR
What is the function of this protein?
Shows anti-apoptotic properties.  Counteract the pro-apoptotic activity of BAX.
What are the official names of this protein?
Anti-apoptotic protein NR13, Apoptosis regulator Nr-13.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHEB2_METHJ
Sequence: MIRVLLVDDSPVTLMVLQSILEKEPDISVIGQAKNGKEAIILASRLAPDIITMDINMPDLDGFATTRQIMERTPVPIIIVSGIDNLEEIRASFRAVEAGALAVFRKPPAYGDPDYEEAVSEFVNAIRTYSEVKVIRRRSNHLKVPKPEASTIQIPFQIHQDIRVIVIGASTGGPQVIQEIISNLPLGFPLPLVLVQHMSPGFIEGLALWLTESTGFPVSIAREGEVLQPGKLYVAPDGIHTGVTSDLRFSFSISPPEHNLRPSVSYLFRSAAKNLGSHVLGILLSGMGSDGAEELLQIRQNGGCTIIQDRDSSFVYGMPGAAEMLNAGMFSLPPVEIARFLRSLSERRQL
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLM2A_MOUSE
Sequence: MEAAAVLPRYLQLRLLLVLLLLVLLRAGPVWPDSKVFSDLDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETVSSGADCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGALYSMDLMKVHAYIQKVASQMNTLEESIKANLSLENKVVKDSVHHLSEQLKSYENQSAIMMSIKKELSSLGLQLLQRDAAAVPATAPASSPDSKAQDTAGGQGRDLNKYGSIQKSFSDKGLAKPPKEKLLKVEKLRKESIKGRIPQPTARPRALAQQQAVIRGFTYYKAGRQEARQEARQEAPKAAADSTLKGTSWLEKLPPKIEAKLPEPNSAKHDDVRLQASEGGNLTPDITTTTTSTSSSTTTTTGTTSTTSTTSTTSTTTPSPITTPWPTEPPLHPEVPSQGREDSCEGTLRAVDPPVKHHSYGRHEGAWMKDPAALDDRIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAVDEHDETQHEVIVLSRLDPADLSVHRETTWKTRLRRNSYGNCFLVCGILYTVDTYNQHEGQVAYAFDTHTGTDAHPQLPFLNEYSYTTQVDYNPKERVLYAWDNGHQLTYTLHFVV
What are the official names of this protein?
Olfactomedin-like protein 2A, Photomedin-1.
Protein: SCX_TITME
Sequence: KKNDYPVDTAKRNCMLDCNVWDDEGYCDNFCKGRKAESGYCYKLKAACYCYGLPDDSPTKTSGRCNPNV
What is the function of this protein?
Inhibits voltage-gated sodium channels (Nav).
What are the official names of this protein?
Sodium channel toxin.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_STAEQ
Sequence: MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQLGTYNPAHVNAPEVKIDEELALKWLHDGAKPTDTVHNILSREGILKKFDEQKNAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: AGAP9_HUMAN
Sequence: MFEDVFSDSGNTGNFDRGKKRRLTIIECGCDINMMIDLAKVADLVLMLIDASFGFEMEMFEFLNICQAHGFPKILGVLTHLDSFKHNKQLKKTKKRLKHRFWTEVYQDKVGLTHELVQSLISTYSTIDAKMASSRVTLLSNSKPLGSEAIDNQGVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGEDLHMHQVRDREMPEVVEIRRSNCTNHCDLGDTSSYHTKVSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKSNGLSKDMDTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYEEKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLEQLLTGWTSWPEMPTGTQR
What is the function of this protein?
Putative GTPase-activating protein.
What are the official names of this protein?
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9, AGAP-9, Centaurin-gamma-like family member 6.
What is the protein family that this protein belongs to?
Belongs to the centaurin gamma-like family.
Protein: VGLU1_XENLA
Sequence: MEFRKEEFKKLAGNTLGHLHRILEKKQKNGETIELTEEGQPVVKEEKHQPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNNTVYKGNKLVIEQAQFNWDPETVGMIHGSFFWGYIVTQIPGGYICQKFAANRVFGFAIVATSTLNMLIPSAARVHFACVICVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYGSFGITWYMFWILVSYESPAQHPTISEEERKYIEESIGESTGFMNPMAKFKAPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSALPHLVMTIIVPIGGQIADFLRTKRIMSTTNVRKMMNCGGFGMEATLLLVVGYSHSRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQYVFLIASLVHYGGVVFYGIFASGEKQPWAEPEETSDEKCGFIHEDELADESEEQTQAHGGYGSYGATQTTSQQNGGWATDWEKKDEFIQDQGKDPYLYGTVAERDLS
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate.  At the synaptic vesicle membrane, mainly functions as an uniporter which transports preferentially L-glutamate but also phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells.  The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane.  In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane that affects the proton electrochemical gradient and promotes synaptic vesicles acidification.  Moreover, may function as a K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular glutamate uptake.  The vesicular K(+)/H(+) antiport activity is electroneutral.  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation.  The symporter activity is driven by an inside negative membrane potential and is electrogenic (By similarity).  Is necessary for synaptic signaling of visual-evoked responses from photoreceptors (By similarity).
What are the official names of this protein?
Vesicular glutamate transporter 1, VGluT1, Solute carrier family 17 member 7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: CALR_CAEBR
Sequence: MKSLCLLAIVAVVSAEVYFKEEFNDASWEKRWVQSKHKDDFGAFKLSAGKFFDVESRDQGIQTSQDAKFYSRAAKFDKEFSNKGKTLVIQYTVKHEQGIDCGGGYVKVMRGDADLADFHGETPYNVMFGPDICGPTRRVHVILNYKGENKLIKKEITCKSDELTHLYTLILNADNTYEVKIDGESAQTGSLEEDWDLLPAKKIKDPDAKKPEDWDEREYIDDAEDVKPEDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIKNPAYKGKWIHPEIENPEYTPDDELYLYENWGAIGFDLWQVKSGTIFDNVLITDSVEEAEAHAAETFDKLKTVEKEKKEKADEEARKVEEEARKKAEEEKEAKKDDDEEEEKEEEEGHDEL
What is the function of this protein?
Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle.  This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER.  Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis.  Protects dopaminergic neurons against oxidative stress-induced neurodegeneration (By similarity).
What are the official names of this protein?
Calreticulin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: EGL44_CAEEL
Sequence: MNSMFCSELQQALPQMSEDVAVTAQTILNGTPPHNHFRKEWLAGAAGTTTPTTTSGGQMMTLSPPAGDGPGSAGSMAPESTSSLSDLSGDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLARKKLRDEQAKKKGDIPSLLQQASPPGGVKSPSAVVFPPVSAAVAAITEISPQSSYSSIVPKVETDQISQQLFKSLPLWSFQQTPGLPIGMDLSQLVFQQSSPDKTVSPVKSEVVEETKPIASSQLTLHSFSAYVKCNKTSLRTELVKIENTLEKDDIDISVFYEKYPKLLRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQEPEPSCSVYRLIDGGGDSDE
What is the function of this protein?
Transcription factor (PubMed:30291162).  Binds to DNA sequence motif 5'-CATNNNNAAATGCAT-3' as a heterodimer with egl-46 (PubMed:30291162).  Represses expression of genes involved in differentiation of touch receptor neurons (TRN), probably acting as a heterodimer with egl-46, perhaps by occupying similar cis-regulatory elements as an unc-86/mec-3 heterodimer (PubMed:30291162).  Plays a role in cell fate specification of neurons, including the hook neuron HOB, and touch receptor neurons (PubMed:12954713, PubMed:30291162).  Involved in male mating behavior, acting in concert with egl-46, via modulation of expression of polycystins lov-1 and pkd-2, homeodomain protein ceh-26, and neuropeptide-like protein nlp-8 (PubMed:12954713).  Acts upstream of egl-46 to prevent touch cell differentiation in FLP neurons (PubMed:11274062).  Plays a role in neuron differentiation by repressing the expression of zag-1 in FLP neurons, probably acting as a heterodimer with egl-46; because zag-1 represses expression of egl-46 and egl-44, together these proteins form a bistable, negative-feedback loop that regulates the choice between neuronal fates (PubMed:30291162).  Also promotes HSN neuron development (PubMed:11274062).  In association with egl-46, regulates cell cycle exit in the neuronal Q cell lineage (PubMed:23946438).  Plays a role in specifying commissural dendrites of the PVD nociceptive neurons, acting in concert with egl-46 (PubMed:29031632).  May be involved in thermal stress response downstream of yap-1 (PubMed:23396260).
What are the official names of this protein?
Transcription enhancer factor-like protein egl-44, Egg-laying defective protein 44.
What are the subcellular locations of this protein?
Nucleus.
Protein: SLMA_SALHS
Sequence: MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKNTSTRLRLIVLLILGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDENLLASQLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: STK26_HUMAN
Sequence: MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHSDDESDSEGSDSESTSRENNTHPEWSFTTVRKKPDPKKVQNGAEQDLVQTLSCLSMIITPAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEKFQKCSADESP
What is the function of this protein?
Serine/threonine-protein kinase that acts as a mediator of cell growth (PubMed:11641781, PubMed:17360971).  Modulates apoptosis (PubMed:11641781, PubMed:17360971).  In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006).  Phosphorylates ATG4B at 'Ser-383', thereby increasing autophagic flux (PubMed:29232556).
What are the official names of this protein?
Serine/threonine-protein kinase 26, MST3 and SOK1-related kinase, Mammalian STE20-like protein kinase 4, MST-4, STE20-like kinase MST4, Serine/threonine-protein kinase MASK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Note=Colocalized with RIPOR1 in the Golgi of serum-starved cells and relocated to cytoplasmic punctae, probably vesicular compartments, along with RIPOR1 upon serum stimulation in a Rho- and PDCD10-dependent manner (PubMed:27807006).
Protein: LUXP_VIBHA
Sequence: MKKALLFSLISMVGFSPASQATQVLNGYWGYQEFLDEFPEQRNLTNALSEAVRAQPVPLSKPTQRPIKISVVYPGQQVSDYWVRNIASFEKRLYKLNINYQLNQVFTRPNADIKQQSLSLMEALKSKSDYLIFTLDTTRHRKFVEHVLDSTNTKLILQNITTPVREWDKHQPFLYVGFDHAEGSRELATEFGKFFPKHTYYSVLYFSEGYISDVRGDTFIHQVNRDNNFELQSAYYTKATKQSGYDAAKASLAKHPDVDFIYACSTDVALGAVDALAELGREDIMINGWGGGSAELDAIQKGDLDITVMRMNDDTGIAMAEAIKWDLEDKPVPTVYSGDFEIVTKADSPERIEALKKRAFRYSDN
What is the function of this protein?
Binds to the signaling molecule autoinducer 2 (AI-2), a furanosyl borate diester, (3a-methyl-5,6-dihydrofuro-[2,3d][1,3,2]dioxaborole-2,2,6,6a-tetraol).  This complex then interacts with the LuxQ sensor protein.
What are the official names of this protein?
Autoinducer 2-binding periplasmic protein LuxP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TIG_MYCA9
Sequence: MKSTVEKLSPTRVRINVEVPFAELEPDFSKAYKELAQQVRLPGFRPGKAPAKLLEARVGRAAVLEQVVNAALPARYSEAVTASDVKPLGQPEIEVTKIEDGQELTFTAEVDVRPEIELPDLSGVAVTVKPVTVEDSEVEAELDALRARFGTLKGVERAAENGDFVSIDLSATVDGKEVEEAATTGLSHEIGSGQLIDGLDEAIIGLKAGEEKVFTTKLAAGEFAGQEAEVTVKVGSIKERELPDADDDFAQLASEFDTIGELKDSLTEQVKGRKRIAQADEIRDETITALLDKIEIPVPEKILEEQIGNNLHEAVHGLDHNEERLNELLQEQGSSREEFDKDMRESATKSIKTELLLDVIADKFDINVDQQDLTERLVLMSRQYGIEPQQLVQYLTQQQQLPGLYVDVRRGKAIAEVIRQAKVTDSTGADVDVDAVLGPRRGGADEAGAEAEAAEEKPAKAKKSADSEKTDKSEKAEKKSKKKSKDDDAE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: MOAC_JANSC
Sequence: MARLTHFDGDGQAHMVDVSGKAVTDRIAVADCYIKMTTQTLDLVEQGTAKKGDVLGVARLAGIMGAKKCADLIPLCHPLPITKVAVDLVPDASLPGVRITATVKTSGQTGVEMEALTAASTAALTVYDMLKAAEKTMEIGGLRVVLKDGGKSGRFEAPEGSAP
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: MUTS_YEREN
Sequence: TLLNEEVSPAVEALESLDPDSLSPRQALEWIYRLKNMV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PYRH_RUTMC
Sequence: MLMSKYKRILLKLSGEALANTENIIDPVALNKVVNIIKSVLSQNVEIAIVVGGGNIFRGAVLAQAGMNRITGDHMGMLATVMNALAIADVCQKNKVDTLVMSGFSIGGGVCDSINHVHAKQALNEGKVVIFCAGTGSPCFTTDTGAALRAIEIDADAVFKATKVDGIYTSDPIKNSDAKRYDSLSFDGAIEKNLQIMDVSAFALCREHDLEICVFSMLENTNTLSDILKGKPLGTIVRK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTK_BOVIN
Sequence: MGSKRSVPSRHRSLTTYEVMFAVLFVILVALCAGLIAVSWLSIQGSVKDAAFGKSHEARGTLKIISGATYNPHLQDKLSVDFKVLAFDIQQMIDDIFQSSNLKNEYKNSRVLQFENGSIIVIFDLLFDQWVSDKNVKEELIQGIEANKSSQLVTFHIDLNSIDITASLENFSTISPATTSEKLTTSIPLATPGNVSIECPPDSRLCADALKCIAIDLFCDGELNCPDGSDEDNKTCATACDGRFLLTGSSGSFEALHYPKPSNNTSAVCRWIIRVNQGLSIQLNFDYFNTYYADVLNIYEGMGSSKILRASLWSNNPGIIRIFSNQVTATFLIQSDESDYIGFKVTYTAFNSKELNNYEKINCNFEDGFCFWIQDLNDDNEWERTQGSTFPPSTGPTFDHTFGNESGFYISTPTGPGGRRERVGLLTLPLDPTPEQACLSFWYYMYGENVYKLSINISSDQNMEKTIFQKEGNYGQNWNYGQVTLNETVEFKVSFYGFKNQILSDIALDDISLTYGICNVSVYPEPTLVPTPPPELPTDCGGPHDLWEPNTTFTSINFPNSYPNQAFCIWNLNAQKGKNIQLHFQEFDLENIADVVEIRDGEGDDSLFLAVYTGPGPVNDVFSTTNRMTVLFITDNMLAKQGFKANFTTGYGLGIPEPCKEDNFQCKDGECIPLVNLCDGFPHCKDGSDEAHCVRLFNGTTDSSGLVQFRIQSIWHVACAENWTTQISDDVCQLLGLGTGNSSVPTFSTGGGPYVNLNTAPNGSLILTPSQQCLEDSLILLQCNYKSCGKKLVTQEVSPKIVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLHMASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVFPPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFGYQCALPNRPGVYARVPRFTEWIQSFLH
What is the function of this protein?
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A).  It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
What are the official names of this protein?
Enteropeptidase, Enterokinase, Serine protease 7, Transmembrane protease serine 15.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: HSL24_DICDI
Sequence: MTIIGSIIKISNPKKFSIGGGSISNNNFISLYSSKKKKCESNSGSGLFGANNLLGGLLGSLGGNNNKQVVYHPAVSATGETIYIHSVCGCE
What are the official names of this protein?
HssA/B-like protein 24.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: DLTA_STRPG
Sequence: MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAFIDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPSLIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPKGVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFALPKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELTVSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDEDGKELASGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDNILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIVVKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINEVNNR
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_XANOM
Sequence: MNEVVIPSVLQDVPVRTSEPRKQNLLDLDREGLERFFADTLGEARYRAHQVMKWIHHRYVTDFDHMTDLGKALRAKLHQHAEVLVPNVVFDKPSTDGTHKWLLAMGTDGKNAIETVYIPDKGRGTLCVSSQVGCGLNCSFCSTATQGFNRNLTTAEIIGQVWVAARHLGNVPHQQRRLTNVVMMGMGEPLMNFDNVVRAMSVMRDDLGYGLASKRVTLSTSGLVPMIDRLSTESDVSLAVSLHAANDALRETLVPLNKKYPIAELMESCARYLRGSKKRDSVTFEYTLMKGINDQPEHARQLARLMRQFDNAVQSKDAGKVNLIPFNPFPGTRYERSGETEIRAFQKILLDAQVLTIVRRTRGDDIDAACGQLKGQVMDRTRRQAEFRRTLEGQADRDAAA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_ACTP7
Sequence: MTKNLYLGVMSGTSLDGVDLCVMDFAKNPPKLTACGFTPMPEDLRTDLSHLLKSRETSLQKLGEIDHRLGLLYAESIKRFLAEHHLSASDIQAIGCHGQTVWHSPNGNFPFTMQIGDMNLVAAHTGITTIADFRRKDMAVGGQGAPLVPAFHEGIFASQERLTVVLNIGGISNISVLTPQQPTIGYDVSVGNALMDSWIELHQAKRYDKNAEWAKTGKLIPTLLDSLLDEPFFKLPAPKSTGRELFNLEWLAKKSANLTAYRPEDVQRTLAEFTAQSVVNELKTLESEKQCLLLVCGGGARNPLLMQRFSELLPKWQVATTDEYGLDIDYVEAAAFAWLAYQRVHNLTSNLPSVTGAKQPVSLGVIYPK
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.