PharMolix/UniProtQA huggingface dataset:
Protein: P53_BOVIN
Sequence: MEESQAELNVEPPLSQETFSDLWNLLPENNLLSSELSAPVDDLLPYTDVATWLDECPNEAPQMPEPSAPAAPPPATPAPATSWPLSSFVPSQKTYPGNYGFRLGFLQSGTAKSVTCTYSPSLNKLFCQLAKTCPVQLWVDSPPPPGTRVRAMAIYKKLEHMTEVVRRCPHHERSSDYSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPYESPEIDSECTTIHYNFMCNSSCMGGMNRRPILTIITLEDSCGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGQSCPEPPPRSTKRALPTNTSSSPQPKKKPLDGEYFTLQIRGFKRYEMFRELNDALELKDALDGREPGESRAHSSHLKSKKRPSPSCHKKPMLKREGPDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.  Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity).  However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity).  In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.  Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression.  Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.  LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation.  Regulates the circadian clock by repressing CLOCK-BMAL1-mediated transcriptional activation of PER2.
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress. Translocates to mitochondria in response to mitomycin C treatment (By similarity).
Protein: IXTPA_METTM
Sequence: MKVTFITGNKHKLSEAEKIFHDTGIELEHADLGYPELQGTLEEVARYGAEHAARIMDGPVIVEDAGLFIRALKWFPGPYSAYVQDTIGNRGILKLMENVEDRYAEFRSAVGFCAPKSEPEVFLGVVKGRIGTEERGTRGFAFDPLFYPEGMDRSFGELSTIEKNRFSHRSRALKKFAQWYTENYEVI
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: GRPE_FRATT
Sequence: MSKQEKSNVEDKSLDIETAAQVETAQESASGALEELSVEEQLERAKDTIKELEDSCDQFKDEALRAKAEMENIRKRAERDVSNARKFGIEKFSKELLPVIDSIEQALKHEVKLEEAIAMKEGIELTAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIPNPEFEDNTIFDVFQKGYMLNGRIVRAAKVVIVKN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_ACIC5
Sequence: MLTLLRLDSSPLETSVSRALTDEFVAAWKAAHPDGVVIVRDLTLAPPPPVDAVWIGACFTPPPQRTAEQNDRLALSDAFLEELERADEYAIGVAMHNFSIPAVLKLWIDQVVRVGRTFAYSDGRPQGLLQGKKATILAATGGVYSAGTPAEGMNFLDPYLKTVLGFLGVRDIQVVTAGGTSQLRNPDVDREAFLEPVLQRVRETAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RS2_LIMRD
Sequence: MSVVSMKQLLEAGVHFGHQTRRWNPKMEEYIFTERNGIYIIDLQKTVKLIDTAYNYMKDVAANDGVALFVGTKKQAQDAIEEEATRAGQYYVNHRWLGGTLTNWKTIQSRIARLKELKKMSEDGTFDVLPKKEVAVLTKQREKLERFLGGIEDMPRIPDVMFIVDPHKEQIAVKEAQKLHIPIVAMVDTNTDPDDIDYVIPSNDDAIRAVRLITSKMADAFVEGKQGQDDAQQETADDNAANETVSEDSLKNLKNSVEGKED
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL29_MYCTU
Sequence: MAVGVSPGELRELTDEELAERLRESKEELFNLRFQMATGQLNNNRRLRTVRQEIARIYTVLRERELGLATGPDGKES
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: EM514_ARATH
Sequence: MAEEQEIVDSLSAEVNPDQKVDMEVETATPKAETGDEKREREETEEEENGGESKKQKVGEEEKSGPVKLGPKEFVTSVAMFDYFVKFLHFWPTDLDVNKYEHMVLLDLIKKGHSEPEKKIGGGIKTFQVRTHPMWKSRCFFLVREDDTADDFSFRKCVDQILPLPENMKTPGANGNGHGGGRGGGGGRRGGRGGGRGGRFRR
What is the function of this protein?
May play a role in ribosome biogenesis and in determining the rate of cell division.  Involved in a process essential for nuclear and nucleolar functions.
What are the official names of this protein?
Protein EMBRYO DEFECTIVE 514, Protein DOMINO 1.
What are the subcellular locations of this protein?
Nucleus. Note=Does not localize in the nucleolus.
Protein: HFLX_AKKM8
Sequence: MFEIREKPEMVERAMLVSVYFDPSEAGEKQAMLDELEDLVSNLGIGIAGKHLIKSRDMHAKFLCGTGKAQEVKQLALDCRADCVVFDNMLSPSQQREWERLVDECVIDREEVILDIFARRARTREATLQVELARMQYSLPRMARMWNHLDRQGGGSGGGKGGGGAARGEGEKQIEVDRRLARARIEAIQRELVLVTRQRATQRKERERQAVATAAIVGYTNAGKSSLLSLVSGSEVMARDMLFATLDTTTRKIELPHGQPLLLTDTVGFIRNLPHRLVEAFKSTLEEAVLADFLIQVVDASDPEAVRHYETTLEVLNELGAGDKPMIVVLNKVDLVPEERRGALETLLAPHFSGRVVPMSVKEGNGEGDLLNACVEMLESRVRRARFLIPYTRSDLVAAMHSEGKVFSTEYVEEGTLLEAVLPVAFYNKLESFLADR
What is the function of this protein?
GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
What are the official names of this protein?
GTPase HflX, GTP-binding protein HflX.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=May associate with membranes.
Protein: YAAI_ECO55
Sequence: MKSVFTISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLALKLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: CRTI_SYNY4
Sequence: MLPAVGVDRPVGRRLQLHARVQQGIGVRSIAWSRVQAVALLAVVRDRQAAVQTPRVGQHQAVVQRNRRRHVRRARQGVADGRQHLGHARRAERDDLCVQEGGGDIEIQALVRAFEQDGVECELDPLALGLADVSAAVGVIGQTGRRLQLLEFIGEDVHRQAKTVRRPTQPGLIGGDGFGIERQGLGLGEDRGAVEAAAAIAGPRRDEDVQVRGKGVFGRDPTRHVVVLEGAVPDEGIGRGEGLGEGRDAPRVQVVVAPAEGRLVAGVTQTARQGQLVGQVIVDLAEHGEAVARLLVQVVVLGPGRIAGPVGVEVDIVRDVEGAHDPVQTTVVVVAQTHFQRGLVQRLIGIEARGRIGRAVAVALHRASRALDVADHRQIQVIAQTMLQRRRHAIDVDAMGRILRRIELVRVVVLARIGDIAVQRRRDTVVLARVAPVAAAEQLHGQVGVRREIEGDSGPAGEQILVAETFTAARIDDGRNLGLGHAGDDRLEARQVARARPGHEAAPCSASTASRTPTVSLRGPPTAASIAR
What is the function of this protein?
This enzyme converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene.
What are the official names of this protein?
Phytoene dehydrogenase, Phytoene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
Protein: SYP_DEIGD
Sequence: MPPMTKAEGKQDKKAQQYGVTPQSVDFNDWYNEVVKKADLADNSPVAGAMVVKPYGTALWENIQRWLDDRFKATGHESLIFPTLIPMNFITKEADHVEGFAPELFTVDRIGTEQLTEPYVLRPTSETIIGYMWSGWLNSYRDLPFLHYQWGSVFRAELRTKAFLRTSEFYWHEGHTAHASEEEARREVRQILDLYHEFCRDILALPVVRGEKTASERFAGAVATYSIEGMMRDGKALQSGTSHYLGQNFSKAFDVKFQTREQREEYAYTTSWAISSRIIGAIIMTHGDDFGLIMPPRIAPIQVVVIPVSRKENFDQMVAEGEKLAHELRAQGLRVKVDRREGVTNGFKYNDWELKGVPVRIELGPRDLEQGVVVVKNRNAEEKETLPREEAIRGMANRLDSIHNWLLQRATDFLLTHTVPADSYEELKNAIEHGNWVRAFHCGNAECEAQIKEDTKATTRNIPLDDAEFFNEREEGVCVKCGQPSAYGKRVIFGRQY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COE3_MOUSE
Sequence: MFGIQENIPRGGTTMKEEPLGSGMNPVRSWMHTAGVVDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVEKEKEPNNEKTNNGIHYKLQLLYSNGVRTEQDLYVRLIDSMTKQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEGTAPSYLENATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFVYTALNEPTIDYGFQRLQKVIPRHPGDPERLPKEVLLKRAADLVEALYGMPHNNQEIILKRAADIAEALYSVPRNHNQIPTLGNTPAHTGMMGVNSFSSQLAVNVSETSQANDQVGYSRNTSSVSPRGYVPSSTPQQSNYNTVSTSMNGYGSGAMANLGVPGSPGFLNGSSANSPYGIVPSSPTMAASSVTLPSNCSSTHGIFSFSPANVISAVKQKSAFAPVVRPQASPPPSCTSANGNGLQAMSGLVVPPM
What is the function of this protein?
Transcriptional activator (PubMed:9151732).  Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).
What are the official names of this protein?
Transcription factor COE3, Early B-cell factor 3, EBF-3, Olf-1/EBF-like 2, O/E-2, OE-2.
What is the protein family that this protein belongs to?
Belongs to the COE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEC2_YEAST
Sequence: MDASEEAKRVSIQVTSLSTQLIESVDKQSHLEEQLNKSLKTIASQKAAIENYNQLKEDYNTLKRELSDRDDEVKRLREDIAKENELRTKAEEEADKLNKEVEDLTASLFDEANNMVADARKEKYAIEILNKRLTEQLREKDTLLDTLTLQLKNLKKVMHSLDNESTVTNNSNRYSTILSDSATSSSTSLNKVPTSYSLASQDIYSGIVYSPSISSIRYDISLYNEFLKFVAALPRCENIKATSTESKLIRRLVNDEIQPILKIDNASGIGWLVKKTLLSLIIDGLVVVEPLSGVNATYQIGYNSSSPAKQATSNMPKMFKFPLDSPPVAVHAACSFCGESRDDIIEHARMYILKTLHKTDDGKEQVTNTYPLCHWCLLKLRQTCEIFAFLRSLKVGAWHLEKLTTQNITKEDLEKFSEVTKHTKRDGRVSSQDKKTKRLSFMAGLGINSSTKNKPKMEIFSSETNAKPGQPTTNIQRAWLQLCKLRCILHWTHIGIWAVDDSISSKIGPLVEDDSDEDQNDAISVRLQDKALWKQDAKRPFSSSSAEESQKSDAFDFESGDMENEITGESSSDESSSDGSSTDNSTADSSSEDESSLADSTTSSADSSSPESIDNGEGDDTVTKDDKSSIKSANNNEENSDCGDKKGRSIIKKKAPQRKIQKKKLLQDLDDLEEQFREESAIDQTEFENAESNVKQNISSKRASSGDENSKKDNNEKTLKTNLTIGDKTQEQIGENSPSSGLHASSSNDDNFDDAQEQQ
What is the function of this protein?
Guanine nucleotide exchange factor for SEC4, catalyzing the dissociation of GDP from SEC4 and also potently promoting binding of GTP.  Activation of SEC4 by SEC2 is needed for the directed transport of vesicles to sites of exocytosis.  Binds the Rab GTPase YPT32, but does not have exchange activity on YPT32.
What are the official names of this protein?
Rab guanine nucleotide exchange factor SEC2, GDP-GTP exchange factor SEC2.
What is the protein family that this protein belongs to?
Belongs to the SEC2 family.
What are the subcellular locations of this protein?
Bud neck. Bud tip. Cytoplasmic vesicle, secretory vesicle. Note=Localizes to sites of polarized growth, namely to the bud neck and to the bud tip of growing buds, and associates with membranes. Colocalizes with secretory vesicles at exocytic sites. Proper localization is dependent on the actin cytoskeleton, MYO2, the kinesin-related protein SMY1, the Rab GTPase YPT32, and the production of post-Golgi vesicles.
Protein: DNAA_HERAR
Sequence: MENFWQACSAQLEQELTPQQYSAWIKPLTPLDYEDGTLRIAAPNRFKLDWVKTQFASRITSIAAQFWEVPVEVQFVLDPRLVAARRPAAQASVVSDRADDVPSNVLEPIPSNATDHTPRRDQSRINTALTFDSFVTGKANQLARAAAIQVANNPGSSYNPLFLYGGVGLGKTHLIHAIGNQVLADNPNVKIRYIHAEQYVRDVVTAYQRKGFDDFKRYYHSLDLLLIDDIQFFGGKSRTQEEFFYAFEALIAAKKQIIITSDTYPKEITGMDDRLISRFDSGLTVAVEPPELEMRVAILLKKAVQEGVTFSDDVAFFVAKHLRSNVRELEGALRKILAYSRFHGKDITIEVVKDALKDLLSVQNRQISVENIQKTVADFFNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIAADRGKSPECNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_CLOB1
Sequence: MSRSVKKGPYIQEVLLKRINEMNKNGEKKVLKTWSRSSTVFPQMIGHTIAVHDGRKHVPVYITEDMVGHKLGEFVLTRTYRGHDDKSEKSSRLR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: YEG7_SCHPO
Sequence: MAILKSALVGFICFLHFFIVNASDNKSLLTEDIMASQVCNGMFAKKGKTSEITLKIDSYTSDFGGAIRLLIFNWKDVNAIGMEDDDGEKHYICNYEDIEAGVCKDDDYGLYLINQTAPHDSIYSAAVDAESMVSPLKYPVEQSGLYCVFTAPLEGSSEAYKITVTWENYFGNLDATDYPHLFLNPILLAINCLIGIWWSFIMFRYRHDLLQVQKYISGVVALSIVCTMVSTGYFYFANSKGYTTGSKVFAFFLSLAQSARQSYFGFLLLIVSLGYSIVVPSLGSLLRKCQILAGLQFVSSCFFLSSLFISPSNKESLVILFAAPVFLITLFAMFLWIVLALNNTIRDLRIRKQTVKAQMYTRLWIVICFGIVAYASIVAANAILIGIYGQMNYYLKYWKLLWFLNYGYTDILVLILMLTILYLWRPTENNRRFAMSEQVAQDVDEFEMTSSLSNDSLHLHHERPTSPANPHIIHGSADEHQALFAVDDESDDDASTLATSKQKPA
What are the official names of this protein?
Uncharacterized protein C26H5.07c.
What is the protein family that this protein belongs to?
Belongs to the LU7TM family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: PRP4B_HUMAN
Sequence: MAAAETQSLREQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSPDDILERVAADVKEYERENVDTFEASVKAKHNLMTVEQNNGSSQKKLLAPDMFTESDDMFAAYFDSARLRAAGIGKDFKENPNLRDNWTDAEGYYRVNIGEVLDKRYNVYGYTGQGVFSNVVRARDNARANQEVAVKIIRNNELMQKTGLKELEFLKKLNDADPDDKFHCLRLFRHFYHKQHLCLVFEPLSMNLREVLKKYGKDVGLHIKAVRSYSQQLFLALKLLKRCNILHADIKPDNILVNESKTILKLCDFGSASHVADNDITPYLVSRFYRAPEIIIGKSYDYGIDMWSVGCTLYELYTGKILFPGKTNNHMLKLAMDLKGKMPNKMIRKGVFKDQHFDQNLNFMYIEVDKVTEREKVTVMSTINPTKDLLADLIGCQRLPEDQRKKVHQLKDLLDQILMLDPAKRISINQALQHAFIQEKI
What is the function of this protein?
Has a role in pre-mRNA splicing.  Phosphorylates SF2/ASF.
What are the official names of this protein?
Serine/threonine-protein kinase PRP4 homolog, PRP4 kinase, PRP4 pre-mRNA-processing factor 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARA5_ARAHY
Sequence: TDSEPGAVILGFKASMTDVYAFPMTIGVRAHEPSDVMSKVRALEPSDMSKRAVAGMKEFYVRAEGIHGTDKSPVITARMKPVHSIGSVRAHFIDGKPTPIKVRAFGPITESMLDEHSMTIGRYEVIASRKYPSDYRHVFGMETSALDRVYAIKGEHRAFSDVSPTHATIEMESPAAHDFLYGRAKVDEPMTIRVAFHSTCM
What are the official names of this protein?
Arachin 25 kDa protein.
Protein: ACPS_EXIS2
Sequence: MIFGIGLDLVELEQIRQTLERQPRIVKRVLTAEEQNRFYTLSDKRQLEYLAGRFAAKEAFVKAFGTGIGADVSWLDLEVLNEASGRPVMTGPFEGTIHLSITHSDHYAAAQVLLEKRSSDVSTNLDRN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_BRUME
Sequence: MNRTRPLPEIKMVSANKTASILEERTGHRFLNLKRLERALTHSSVQAPARANYERLEFLGDRVLGLTVAEMLFEAFPEASEGELSVRLNALVNAETCAAIADEIGLADLIHTGSDIKSLNDKRLLNVRADVVEALIATIYLDGGLEAARSFIQRYWKKRSLETGAARRDAKTELQEWAHQQGNVHPVYAILSRSGPDHDPLFLVEVTVKGFAPEKGEGRSKRIAEQSAAEAMLYREGVWKRDGSA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHYS2_METMA
Sequence: MHHNVFTNTPTIPIDVKDRSVSELMDGMLRTGFQGRKLAESVQAWSNMLKEKDTTVLMGLSGAMVPAGMRRVISYLIRERMIDCLVSTGANLFHDSHEALGRKHYVGSHLANDEKLFEHGVDRIYDVFAVEEEFRNADNLIADFAEEIGEISCSSREFMYLLGKELVRRGAAEDSIVVSAYRHNVPIFVPALSDSSIGIGLTIARRRGLKLEIDQIKDVDEITQIVEKSGHTGVVYVGGGVPKNFIQQTEVIASILGMDVPGHEYAIQYTSDSPHWGGLSGCTFDEAVSWGKVAAQAKKVQVFVDATIALPIVAHALHEKTRGVKRTAPVFSWDGPEGLEIAYNE
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase 2, DHS 2.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: TYSY_STRPM
Sequence: MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFAEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_XANCP
Sequence: MSEIQSLTAQALADVAAAHTPDQLETLRVALLGKNGSITAQLKQLGTLPADQRKAAGEAINLARDALTTALSERKQVLETAALDARLEGERIDVTLPGRRGERGGLHPVTRTLERIVEIFARLGYELSDGPEIEDDWHNFEALNFPPHHPARAMHDTFYFGDGRLLRTHTSGVQVRYMDTAVATKSGPPLRMIAAGKVYRSDSDQTHSPMFHQVEGLLVDEHSNFADLKGTLSEFVRAFFERDFEMRFRPSYFPFVEPGAEVDIAWQQPDGSTRWLEVLGCGMVHPNVLRSVGIDPERYTGFAFGLGVERFAMLRYGVNDLRAFFENDVRFLRQFA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAMB_VIBPH
Sequence: RCYQRKDIHITDFYFLNTSGTGGGIENLSVGNQKLSLAIIQDGEDQNGAGYIADARLANIGLWEDASLEVALGINFSTESKNGKYDGDDGLLASGIIHQNMSNGFNQTVVQVGTAGYGIQMANFWGAGAYYDRSGDQNDASGYRVINWGVMNLGENWEMGHQLAYLAGSDLGTTKYDSSQYSIVARPMYKWNDTMRTIFEAGYNAGEVDDVDFGGAKFTVAQAWAMGDSFWARPEIRVYGSYLMDLENDSFGEVKNDTGVVTAAGTDNDFVVGIH
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin, Outer membrane protein S.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RS4_TETTH
Sequence: ARGPKKHLKRINAPKSWMLNKLGGIWATRPSQGPHKLRESLPLSVLLKERLNYALNGRDVTLILNDKEGNVFVDQKVRRDKGYPTGLMDVVRIEKTDQSFRILYDTKGRFVLKSLSKEEAKYKLLKVTAKAIGPNQIPYIVTHDSRTIRFPNPEIKIGDTLKYDLVNNKIENFAHLESGNVCYIQQGNNIGRVGIIQHIEKHQGSFDICHVKDAKGNAFATRLGNIFVLGQGKKLYIELPSGDGVRETILEERKRKFSY
What are the official names of this protein?
40S ribosomal protein S4, 40S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: GPGS_MYCS2
Sequence: MGHRWLTDHSWNRPSWTVADLEAAKAGRTVSVVLPALNEEETVGSVVETIKPLLGGLVDELIVLDSGSTDETEIRAVAAGAKVVSREAALPEVPPQPGKGEVLWRSLAATTGDIIAFVDSDLIDPDPMFVPKLLGPLLTCDGVHLVKGFYRRPLKVSGAEDANGGGRVTELVARPLLASLRPELNCVLQPLGGEYAGTRELLTSVPFAPGYGVEIGLLVDTYDRLGLDGIAQVNLGVRAHRNRPLTELASMSRQVIATLLSRCGISDSGVGLTQFFADGDDFTPRVSSVSLADRPPMTTLRPR
What is the function of this protein?
Involved in the biosynthesis of 6-O-methylglucose lipopolysaccarides (MGLPs) (PubMed:18221489, PubMed:19421329).  Catalyzes the transfer of the glucose moiety from a nuleotide sugar such as UDP-alpha-D-glucose to the position 2 of 3-phospho-D-glycerate (3-PGA) to form glucosyl-3-phosphoglycerate (GPG).  It can use UDP-glucose, ADP-glucose and GDP-glucose as sugar donor substrates with decreasing affinity and with 3-PGA as an acceptor.  D-glycerate can only be an acceptor with ADP-glucose and at a very low rate (PubMed:18221489).
What are the official names of this protein?
Glucosyl-3-phosphoglycerate synthase, GpgS.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: RL21_HALMA
Sequence: MPSSNGPLEGTRGKLKNKPRDRGTSPPQRAVEEFDDGEKVHLKIDPSVPNGRFHPRFDGQTGTVEGKQGDAYKVDIVDGGKEKTIIVTAAHLRRQE
What is the function of this protein?
This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains.
What are the official names of this protein?
50S ribosomal protein L21e, Hl31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.