PharMolix/UniProtQA huggingface dataset:
Protein: RPOC1_DAUCA
Sequence: MIDQYKHQQLRIGSVSPQQISTWANKILPNGERVGEVTKPYTFHYKTNKPEKDGLFCERIFGPIKSGICACGNYRVIGDKKKDRKSCEQCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKRLPSYIANLLDKPLKELEGLVYCDFSFARPIAKKPTFLRLRGLFEYEIQSWKYSIPLFFTTQGFDTFRNREISTGAGAIREQLADLDLRIIIDSSLVEWKELGEDGPTGNEWEDRKVGRRKDFLVRRMELAKHFIRTNIDPKWMVLCLLPVLPPELRPIVQIDGGKLMSSDINELYRRVIYRNNTLTDLLTTSRSTPGELIMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLYQCGLPREIAIELFQTFVIRSLIRQQLASNIGVAKSKIREKKPIVWEILREVMRGHPVLLNRAPTLHRLGIQAFQPVLVEGRAICLHPLVRKGFNADFDGDQMAVHVPLSFEAQAEARLLMFSHINLLSPAIGDPISVPTQDMLIGLYVLTSGNRRGICVNRYNPSNHRNQNKRIYENNYKYTKEKEPFFCNSYDAIGAYRQKRINLDSPLWLRWRLDQRVIAAREAPLEVHYESLGTYYDIYGQYLIVRSIKKEILSIYIRTTVGHISIYREIEEAIQGFCQAC
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL20_PSYWF
Sequence: MARVKRGVQANRRHKKILKRAKGYYGARSRVYRVAVQAVTKAGQYAYRDRRNKKRTFRRLWIARINAGARLNGLSYSRFINGLKKANIEIDRRVLADIAMHDAAAFTALTEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RSMG1_SYNFM
Sequence: MRETPSPQTLRAFLNGHGIAVSPQQAEMLFEHVRLMLEWNLRSNLTRITEFDRILTAHLLDSLLPARWLPLTGKTLDVGTGAGFPGVPLKILHPETQMYLLESNRKKVSFLKVLLAGLSLPGIHVLHGRWEEPEGWFTEEDERFTAVIMRAVRVEPGHLTRLAPRVLRPGGVFASWAGSGTETALENRRTHAYPAPAETRSYELPGMSAPRRLYLWRMEG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G 1, 16S rRNA 7-methylguanosine methyltransferase 1, 16S rRNA m7G methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAN_POPEU
Sequence: ALPNQQTVDYPSFKSNYNFEKPFLYLAR
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein Ran.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: F163B_HUMAN
Sequence: MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEDEEEPDFAVHSHLPPLHSNRNLVLTNGPALYPTASTSFSQKSPQARALCRSCSHCEPPTFFLQEPPEEEEDVLNGGERVLYKSVSQEDVELPPGGFGGLQALNPNRLSAMREAFARSRSISTDV
What are the official names of this protein?
Protein FAM163B.
What is the protein family that this protein belongs to?
Belongs to the FAM163 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RPIA_PSEF5
Sequence: MTQDQLKQAVAQAAVDLILPKLDDKSIVGVGTGSTANCFIDALALHKGTFDGAVASSEATAARLKGHGIPVYELNTVSDLEFYIDGADESDEHLNLIKGGGAALTREKIVAAVAKTFICIADASKLVPVLGNFPLPVEVIPMARSHVARELVKLGGDPVYREGVITDNGNIILDVHNMQITNPVELESQINAIVGVVTNGLFAARPADVLLLGTAEGVKTLKA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RBL_ORYSI
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIWKAIKFEFEPVDKLDS
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MYS_BOMMO
Sequence: SKYESEGVARSEELQEVHQAFADAGRKPI
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin heavy chain, muscle.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: SG11A_MOUSE
Sequence: MIPRLLPFFASLLFAALLFPGDIPPGIRNTVCLMQQGHCRLFMCRSGERKGDICSDPWNRCCVPYSVKDRR
What is the function of this protein?
Has antimicrobial activity against E. coli (By similarity).  Plays a role in the defense response in the male reproductive tract, contributing to sperm maturation, storage and protection (By similarity).
What are the official names of this protein?
Sperm-associated antigen 11A, Antimicrobial-like protein Bin-1b, EP2 protein.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_LACJO
Sequence: MSVKIRMRRMGSKRKPFYRIVVADSRMPRDGRFIEEVGYYNPLTNPDEVKLEEDKIFEWLEKGAQPSDTVRSLLSKAGLMTRYHDAKYGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: A1L2_LOXSA
Sequence: WIMGHMVNAIYQIDEFVNLGANSIETDVSFDDSANPEYTYHGVPCDCRRWCKKWEYFNNFLKALRKATTPGDSKYHEKLVLVVFDLKTNSLYDHQAYDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPNLSHYKLITGFKETPKNEGHPELKEKVGFDFSGNDNIDQVAKAYKKAGVTGHVWQSDGITNCIASFIRGLDRAKEAVANRDSSNGFINKVYYWTVDKRATTREALDAEVDGIMTNDPDVIADVLNESAYKAKFRIATYDDNPWETFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LsaSicTox-alphaIB2ii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTND_RAT
Sequence: MVQAWYMDESTADPRMPHRAQPDRPVGLEQLRTLGVLYWKLDADKYENDPELEQIRKTRNYSWMDIITICKDSLPNYEEKIKMFFEEHLHLDEEIRYILEGSGYFDVRDKEDKWIRISMEKGDMITLPAGIYHRFTLDEKNYVKAMRLFVGEPVWTPYNRPADHFDARVQYVKFLEGTA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.  Also down-regulates cell migration mediated by MMP14.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD, Androgen-responsive ARD-like protein 1, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1, MTCBP-1.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the plasma membrane when complexed to MMP14.
Protein: CALMF_NAEGR
Sequence: MSREAISNNELTEEQIAEFKEAFSLFDKDGDGTITTSELGTVMRSLGQNPTEAELHDMINEVDADGNGTIDFTEFLTMMAKKMKDTDNEEEIKEAFKVFDKDGNGFISAQELRHVMCNLGEKLTDEEVDEMIREADIDGDNQINYTEFVKMMMQK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, flagellar, CAM-1.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum.
Protein: RSMJ_SHESR
Sequence: MAAISTCQTVIPLPIPVFFNQQFPTLVDICARWQLVFDADAPFELRFESDTLTLHKRDEPKLDGIIVDFVTGAVAHRRKFGGGRGQSIAKAVGLKQGVTPKVVDGTAGLGRDAFVLASLGCTVTMVERHPVVAALLEDGLRRAYQDAEIGDWMRERMQLFHGSSLEALAKLEQEVDVVYLDPMYPHRDKSALVKKEMRVFQTLVGADLDADGLLAPAMALASKRVVVKRPDYAEDLAGVKPSMVIETKKNRFDVYVKSAMK
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_BACC7
Sequence: MAVITKIEVQKRSKERFNIYIDKGQGEEYGFSVNEVILIKHGLQKGLEIDEIALGNILYNEEVQKAYLQAISYLSYQMRTKLEIEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQIENALILIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEELKDEKDDEKQREALHYHGNKYYEKYKKYDGWTFENKMKQALYRKGFSIDEIEIFLQMKREEG
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_LEVBA
Sequence: MKVSIFSNNGLSSQKVATALQKGLTAAGVPIDSLDPDVVVTVGGDGTLLSAFHHYNDRLDKVRFVGIHTGHLGFYTDWRDYEVQELIDSLAQDNGQSVSYPLLTIQVEYADGTHPDQALALNESTIKKVSGTMVADVYIKDELFESFRGDGLCISTPTGSTAYNKSVGGAVLNPRFNAVQMAEIASINNLVFRTLGSPLIIPADEWIRIEPADPTDNVLMCDQLGIEGRPIKAIMYRIARQRIAFAEYRHTHFWQRVESSFIGRENA
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3_STAA1
Sequence: MAMTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYTNARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_FRAT1
Sequence: MRVLHVCSELYPILKTGGLADVTAALPPALAGFGVDSRVLVPGFPAFINAIKDKQLLINIPSRFGAEEINIFLAKISNTKIDIYVIDAPSLFARPGNPYADSSNQAYADNYLRFALLGWVAARISEGLDAKWKPEIVHSHDWHAGLVPAYIKASELASGKKAVKTVFTVHNLAYQGLFPMSVFAELDLPGIFLSMNGLEFYGQVSFMKAGLYFADKITTVSPTYAKEIQIYEQGCGLEGLLADRHNDLYGVLNGVDPQIWNPKKDSLIATNYSSTTVATGKAKCKLALQQMMGLAEKEDALLFGIVTRLTEQKGLNLLIEAIGEITSRGGQIVLLGSGDKALEEVFLAAAKKYSKSIAVQIGYDEEQAHRIIAGSDVIMVPSRFEPCGLTQLYGLTYGTLPLVHKVGGLADTVIDSSLENLADGTATGFVFDEFSVESLTLAIRRAFALYNRKTDWKKVRKTAMQQQVTWDSSAEKIYQIYKNLVRENN
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: ODFP2_MOUSE
Sequence: MSASSSGGSPRFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGTLLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKMLKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSQKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKASYANVFGDAPYTSSYLTSSPIRSRSPPA
What is the function of this protein?
Seems to be a major component of sperm tail outer dense fibers (ODF).  ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.  May have a modulating influence on sperm motility.  Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles.  Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes.  Required for the formation and/or maintenance of normal CETN1 assembly (By similarity).
What are the official names of this protein?
Outer dense fiber protein 2, 84 kDa outer dense fiber protein, Cenexin, Outer dense fiber of sperm tails protein 2.
What is the protein family that this protein belongs to?
Belongs to the ODF2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell projection, cilium, flagellum. Note=Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.
Protein: DPHB_THEGJ
Sequence: MALYFIGLGLYDERDITLKGLKTARKCDKIFAEFYTSLLAGTTMERIEGLIGKPIIRLSREDVELNFEKIVLPEAKEKDVAFLTAGDPMVATTHSDLRIRAKKAGVESYVIHAPSIYSAVAVTGLQIYKFGKSATVAYPERNWFPTSYYDVIKENRERGLHTLLFLDIKAEQNRYMTANEAMEILLQVEDMKKEGIFTPETLVVVLARAGSLNPTIRAGYVKDMIHEDFGRQPHVLIVPGRLHVVEAEYLVEFAGAPEEILEEV
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: ADHC_MYCTU
Sequence: MSTVAAYAAMSATEPLTKTTITRRDPGPHDVAIDIKFAGICHSDIHTVKAEWGQPNYPVVPGHEIAGVVTAVGSEVTKYRQGDRVGVGCFVDSCRECNSCTRGIEQYCKPGANFTYNSIGKDGQPTQGGYSEAIVVDENYVLRIPDVLPLDVAAPLLCAGITLYSPLRHWNAGANTRVAIIGLGGLGHMGVKLGAAMGADVTVLSQSLKKMEDGLRLGAKSYYATADPDTFRKLRGGFDLILNTVSANLDLGQYLNLLDVDGTLVELGIPEHPMAVPAFALALMRRSLAGSNIGGIAETQEMLNFCAEHGVTPEIELIEPDYINDAYERVLASDVRYRFVIDISAL
What are the official names of this protein?
NADP-dependent alcohol dehydrogenase C.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: GPMA_STAAT
Sequence: MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: CRL_YERE8
Sequence: MTSTSAHPKSKLMKRFAALGPYLREGQCQNDRFFFDCLAVCVNVKLAPEKREFWGWWIELEPAADHFTYVYQLGLFNKDGDWKAEKIKDPEVQEKLETTLRGFHKRLAEMLTSIEMRLEPAQDFSEQPVKLSA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_CLOD6
Sequence: MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFGSPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREGLKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLIAEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYILITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKAPGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGSGDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKLRIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPLRQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAASIASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_ACIC5
Sequence: MNSTVKTIVFWVFILACCILLWQVFQRSSNTGKEQEISFSQFLNDAQQGQIHDVTVVGGEVHGHFRSANAAFHVEVPTNYPQLYDILNKNHVAVTVKDNSGSPWWSILIQFSPVLVLVALWFFMIRQMQSGGNKALSFGKSRARLLSMQQKKVTFKDVAGVDEAKEELKEIIEFLREAQKFQKLGGRIPKGVLLVGPPGTGKTLLARAVAGEANVPFFSISGSDFVEMFVGVGASRVRDLFEQGKKNAPCIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFEANDGVILVAATNRPDVLDPALLRPGRFDRRVVVGRPDVRGREEVLRVHAKKVPLAEDVDLRVLARGTPGFSGADLANMVNEGALSAARANRKVVTMQDFESAKDKVLMGAERKSMLLTDEEKRVTAYHESGHAIVAAMRKHADPLHKVTIIPRGMALGVTMQLPEEDKHTVTKDYLETQLAILMGGRIAEEIFLHQMTTGAGNDIERATEMARKMVCEYGMSRLGPLTYGKKEEQIFLGREIAQHRDFSEETARQIDAEVRSLVDEAYRASYQLLNDNQPIMHKMAAALLERETIDANDIRMIIEGKDLPPLKPSGGSGTATTDDVQQVLKPSSDRGAGGLPEGSPSPA
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: YCHJ_SHIDS
Sequence: MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQDADYLIKTWHPSCGAAALRAELIAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFIEGGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKIKKCCGQ
What are the official names of this protein?
UPF0225 protein YchJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: RPOB_CITSI
Sequence: MLGDGNAGMSTIPGLNQIQFEGFCRFIDQGLTEELYKFPKIEDTDQEIEFQLFVETYQLVEPLLKERDAVYESFTYSSELYVSAGLIWKSRGDMQEQTIFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELGHNGISVYTGTIISDWGGRFELEIDRKARIWARVSRKQKVSILVLSAAMGSNLREILENICYPEIFLSFLTNKEKKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFHQRCELGKIGRRNMNQRLNLNIPQNNTFLLPRDVLAAVDHLIGLKFGMGTLDDMNHLKNKRIRSVANLLQDQFGLALVRLENVIRGTICGAIRHKLMPTPQNLVTSTPLTTTYDSFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTASFRVRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGYWGSLESPFYEIFEKSKKVRMLYLSPSRDEYYMVAAGNSLALNQGSPEEQVVPTRYRQEFLTIAWEQVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLVRSEKCIVGTGLEPQVALDSGVPAIAEHEGKIIYTDIDKIVLSGNGNTYSIPLIMYQRSNKNTCMHQKPQVGRGKCIKKGQVLADGAATVGGELALGKNILVAYMPWEGYNFEDAVLISERLIYRDIYTSFHIRKYEIQTHVTSQGPERITNEIPHLEARLLRNLDKNGIVMLGSWVETGDILVGKLTPQAAKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWVQKKGGSSYNPETICVYISQKREIKVGDKVAGRHGNKGIVSKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFECSLGLAGGLLNRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEEPVLIGKPYILKLIHQVDDKVHGRSSGHYALVTQQPLRGRSKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGETIPNPEDAPESFRLLVRELRSLALELNHFVVSEKNFQINKKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.