PharMolix/UniProtQA huggingface dataset:
Protein: PMA1_NICPL
Sequence: MGEEKPEVLDAVLKEAVDLENIPIEEVFENLRCTKEGLTATAAQERLAIFGYNKLEEKKDSKLLKFLGFMWNPLSWVMEAAAIMAIALANGGGKPPDWQDFVGIITLLIINSTISFIEENNAGNAAAALMARLAPKAKVLRDGRWKEEDAAVLVPGDIISIKLGDIIPADARLLEGDPLKIDQSALTGESLPVTKGPGDGVYSGSTCKQGEIEAIVIATGVHTFFGKAAHLVDSTNQVGHFQKVLTAIGNFCICSIAVGMIIEIIVMYPIQHRAYRPGIDNLLVLLIGGIPIAMPTVLSVTMAIGSHRLAQQGAITKRMTAIEEMAGMDVLCSDKTGTLTLNKLTVDKNLIEVFAKGVDADMVVLMAARASRTENQDAIDAAIVGMLADPKEARAGIREIHFLPFNPTDKRTALTYLDGEGKMHRVSKGAPEQILNLAHNKSDIERRVHAVIDKFAERGLRSLGVAYQEVPEGRKESAGGPWQFIGLLPLFDPPRHDSAETIRRALNLGVNVKMVTGDQLAIGKETGRRLGMGTNMYPSSALLGQTKDESISALPIDELIEKADGFAGVFPEHKYEIVKRLQARKHICGMTGDGVNDAPALKKADIGIAVDDATDAARSASDIVLTEPGLSVIISAVLTSRAIFQRMKNYTIYAVSITIRIVLGFMLLALIWKFDFPPFMVLIIAILNDGTIMTISKDRVKPSPLPDSWKLAEIFTTGIVLGGYLAMMTVIFFWAAYKTNFFPHVFGVSTLEKTATDDFRKLASAIYLQVSIISQALIFVTRSRSWSFVERPGFLLVIAFVIAQLVATLIAVYANWSFAAIEGIGWGWAGVIWIYNLVFYIPLDIIKFFIRYALSGRAWDLVFERRIAFTRKKDFGKEQRELQWAHAQRTLHGLQVPDTKLFSEATNFNELNQLAEEAKRRAEIARLRELHTLKGHVESVVKLKGLDIETIQQAYTV
What is the function of this protein?
The plasma membrane ATPase of plants and fungi is a hydrogen ion pump.  The proton gradient it generates drives the active transport of nutrients by H(+)-symport.  The resulting external acidification and/or internal alkinization may mediate growth responses.
What are the official names of this protein?
Plasma membrane ATPase 1, Proton pump 1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRF_STRPZ
Sequence: MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQKATDDAIKEIDRMTAEKEKELLSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQHA_ECOBW
Sequence: MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPNIFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DHP1_CAEBR
Sequence: MSPPLVIKNGTVVNEDGMFKADVLVKNGIIVEVSPKIIALPEMEIIDATDRLVIPGGIDPHTHMQMPYAGEVTKDDFLRGTQAAVAGGTTMIIDFCCPDHRNGESLMAGYARWRSWADPKVCCDYGLSVAITQWRPETADQMAVITSPEFGVNSFKFYMAYEGTLMVRDDEMYRAMQECAKLRALARVHAENGSVIKEREIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAAAAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDGCQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSATAAKIFNIYPKKGRIAVGSDADIVIFNPNATRTISAETHHHNLDFNIFEGIKCHGVAEITISRGRIVWANGQLQTVPGSGKFVPLLANSPFVFSSHEIREKKKEPRIVERLE
What are the official names of this protein?
Dihydropyrimidinase 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPB_PSEFS
Sequence: MRRIAVMGAAGRMGKTLVEAVQQRSPASGLTAAIVRPGSTLIGADAGELASLGRIGVSLSGNLEQVADEFDVLIDFTLPDVMLKNLAFCRKAGKAMVIGTTGLTLEQKQLLAEAGKDIPIVFAANFSVGVNLSLKLLDLAARVLGDEADIEIIETHHRHKIDAPSGTALRMGEAIADALGRDLSKVAVYGREGHTGARARDTIGFATVRGGDVVGDHTVLFASEGERLEITHKASSRMTFAKGAVRAALWLEGRAAGLYDMRDVLDLH
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_ACAM1
Sequence: MPYYRRRVSPIKPGDPIDYKDVDLLRRFITERGKILPRRITGLTARQQRDLTRAIKQARVLALLPFINREG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: KUP_ACIAC
Sequence: MQRSKSSLAALTLGAIGVVYGDIGTSVLYAVKEVFGSGHVAFTPQNVYGVLSILFWTLTTIVSLKYVVLVLRADNNGEGGLIAMLALASQAVKDKPRLRSALLGIGVFGTSLFYGDGVITPAISVLSAVEGLEVVSPHFGKAVIPLTLIVLFCLFAVQKRGTSGIGRYFGPVTLVWFTSIAALGVPHIVGHPEILGALSPHHALGFIWRSPGTSFIILGAVVLCVTGAEALYADLGHFGKKPIRLAWFSVAMPALTINYFGQGALLLAEPEAVKNPFYMMAPDWALIPLVIMATMATVIASQALITGAFSVTKQVIQLGYLPRLNILHTSVRDTGQIYIPFVNWALFLAIVLAVVMFRSSSNLAAAYGIAVTLDMLITTVLTFFVIRYGWRYPLALCIAATGFFFLVDLAFFGSNLLKLLQGGWFPLMIGSIVFMLMMTWKRGRELLNEKLRADAIDLRDFLTAVFVNPPTRVDGTAVFLTAEPGAVPNALLHNLKHNKVLHQQNLFVTVRNHEVPWIGLDKRLQVEALGGDCWQVMVHYGFKNDPDLPGALALMRGRGCELESMTTSYFLSRDVVTPTIGSGMAPWREKLFAQMHHNASGAAGFLNLPSNSVVELGSKIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS14Z_BORRA
Sequence: MAKKSMIVKALRKPKYKTRQKNRCKLCGRPKGYMRDFSMCRICFRNHASAGLIPGVSKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: LPTA_ECO57
Sequence: MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQSLDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNGKPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRVTTVLVPSQLQDKNNKGQTPAQKKGN
What is the function of this protein?
Involved in the assembly of lipopolysaccharide (LPS).  Required for the translocation of LPS from the inner membrane to the outer membrane.  May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
What are the official names of this protein?
Lipopolysaccharide export system protein LptA.
What is the protein family that this protein belongs to?
Belongs to the LptA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MTHK_METTH
Sequence: MVLVIEIIRKHLPRVLKVPATRILLLVLAVIIYGTAGFHFIEGESWTVSLYWTFVTIATVGYGDYSPSTPLGMYFTVTLIVLGIGTFAVAVERLLEFLINREQMKLMGLIDVAKSRHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDPTRVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAERYENIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRMVEVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRAGDIILGIGKPEEIERLKNYISA
What is the function of this protein?
Calcium-gated potassium channel.
What are the official names of this protein?
Calcium-gated potassium channel MthK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRM3_HUMAN
Sequence: MAALVRPARFVVRPLLQVVQAWDLDARRWVRALRRSPVKVVFPSGEVVEQKRAPGKQPRKAPSEASAQEQREKQPLEESASRAPSTWEESGLRYDKAYPGDRRLSSVMTIVKSRPFREKQGKILLEGRRLISDALKAGAVPKMFFFSRLEYLKELPVDKLKGVSLIKVKFEDIKDWSDLVTPQGIMGIFAKPDHVKMTYPKTQLQHSLPLLLICDNLRDPGNLGTILRSAAGAGCSKVLLTKGCVDAWEPKVLRAGMGAHFRMPIINNLEWETVPNYLPPDTRVYVADNCGLYAQAEMSNKASDHGWVCDQRVMKFHKYEEEEDVETGASQDWLPHVEVQSYDSDWTEAPAAVVIGGETYGVSLESLQLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQLRGRAEDLSRDRSYH
What is the function of this protein?
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
What are the official names of this protein?
rRNA methyltransferase 3, mitochondrial, 16S rRNA (guanosine(1370)-2'-O)-methyltransferase, 16S rRNA [Gm1370] 2'-O-methyltransferase, RNA methyltransferase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: B3GA3_MOUSE
Sequence: MKLKLKNVFLAYFLVSIAGLLYALVQLGQPCDCLPPLRAAAEQLRQKDLRISQLQADLRRPPPVPAQPPEPEALPTIYVITPTYARLVQKAELVRLSQTLSLVPRLHWLLVEDAESPTPLVSGLLAASGLLFTHLAVLTPKAQRLREGEPGWVRPRGVEQRNKALDWLRGKGGAVGGEKDPPPPGTQGVVYFADDDNTYSRELFKEMRWTRGVSVWPVGLVGGLRFEGPQVQDGRVVGFHTAWEPNRPFPLDMAGFAVALPLLLAKPNAQFDATAPRGHLESSLLSHLVDPKDLEPRAANCTQVLVWHTRTEKPKMKQEEQLQRQGQGSDPAIEV
What is the function of this protein?
Glycosaminoglycans biosynthesis.  Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate.  Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans.  Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins.  Stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP-GlcUA) during completion of linkage region formation.
What are the official names of this protein?
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3, Beta-1,3-glucuronyltransferase 3, Glucuronosyltransferase I, GlcAT-I, UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase, GlcUAT-I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Golgi apparatus, cis-Golgi network.
Protein: TRPB_AZOPC
Sequence: MKEKLTNNTFQVNEKGYYGKFGGAFIPEILHENINRLQKAYKSIIESQEFIEQYYKLLHDYAGRPSPLYFAKRLSDKHKCRIYIKREDLNHTGSHKINNTLGQILLSRKMGKTRIIAETGAGQHGVASATVCALMDMKCVVYMGKTDINRQNLNVRKMEMLGATVIPVTSGNMTLKDATNEAIRDWCSNPDDTHYIIGSTVGPHPYPDMVARFQSIISKEIKSQLPEKENRNYPDYLIACIGGGSNAAGTIYEYLYDNRVKIILAEAAGQGIHSGHSAATIHLGKIGIIHGSKTLIMQTSDGQIEEPYSISAGLDYPGIGPMHAHIAKQGRSEILAIDDNEALSAAMELTRLEGIIPALESAHALGIFQKKQFKTNDVIVVCLSGRGDKDMETYYK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: THEM6_RAT
Sequence: MMELLVVSLSLALAFFALLDGWYLVRVPCAVLRARLLQPRVRDLLAEQLYAGRVLPSDLDLLLHMNNARYLREADVARAAHLTRCGVLGALRDLGAHTVLAASCARYRRSLRLFEPFEVHTRLLGWDDRAFYLEARFVSLRDGFVCALLRFRQHVLGTSPDRVVQHLCKRRVEPPELPEDLKHWITYNETSSQLLRAESGLSDRKDQ
What are the official names of this protein?
Protein THEM6.
What is the protein family that this protein belongs to?
Belongs to the THEM6 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RRP36_CANGA
Sequence: MSYYFKNIKPSYDDDSDEVSDEQDLDAILASKMRGRAESDDESSEEEDDGLSKLSFGSLKKAEDQLEEEERGELRKKRKPQHSKPINDEPEVRHKVYKEEEQEESDSESGSDDGAFFEEDERDNHSRPKNKNSKKRKHAPTEHSSKKRVSKIRDIPGLEIARQAKSGIYQDVRFTKATGEATDFSVIRRRYKFLDEYREKEIEEMERLLNDKKFVNKAESREIENMKEKVRSMKSRLQSVKNRELEQQIVKDYEGKLNEGNKNRFHLKKAEKRKVIQKWKFDHMKAKQREKVMERKRKKKLGKEFKQFEFHNR
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RS3_HAEIG
Sequence: MGQKVHPHGIRLGIVKPWSSTWFANTQDFADNLEGDFKVRKFLNKELANASVSRITIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRNAVSKIAGVPAQINIAEVKKPELDAKLVADSIASQLERRVMFRRAMKRAVQSAMRLGAKGIKVEVSGRLGGAEIARSEWYREGRVPLHTLRADIDYNTAEAHTTYGVIGVKVWIFKGEILGGMAAVAQSEQQPADKPKKAPRGKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MTND_BACCN
Sequence: MAQIRIHEINTRIENEKEVQLFLQKEDVLYEKWDISKLPAHLQNNYALTDENKEEILTLFSNEIADVSQRRGYKAHDIISLSSATPNLDELLINFKQEHHHTDDEVRFIVSGHGIFAIQGKDGRFFDVELEPGDLISVPENVRHYFTLQDDRQVVAIRIFVTTAGWVPIY
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: MURA_SACD2
Sequence: MDKLIIEGGSRINGEIRISGSKNSGLPILAATLLASGPMHICNLPHLNDITTMLALLRCMGVGVTIDEKMCVEVDPTSITEFEAPYELVRTMRASILVLGPMLARFGKADVSFPGGCAIGSRPVDIHLRGLEAMGAEIEVDGGYIRAKAPNGLKGARYLMDTVTVGGTENLLMAAVLAEGTTILENAAREPEIVDLAECLIAMGAKIKGVGTDRLEIEGVKTLNGCTYEVMPDRIETGTYLVAAAATGGWVKLRDTRADILEAVLLKLEEAGAEITVGEGTIELAMHGKRPKAVSFKTAPYPAFPTDMQAQFTAMNAIAEGTSSVVETIFENRLIQVHELNRMGANIRLEGNTAIITGVEKLKAAPVMASDLRASASLVIAGMLAEGDTLVDRIYHIDRGYECIEEKLQALGVRIRRVPG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUB8_ARATH
Sequence: MAFDLPNDFRCPISLEIMSDPVILQSGHTFDRVSIQQWIDSGNRTCPITKLPLSETPYLIPNHALRSLILNFAHVSLKESSRPRTQQEHSHSQSQALISTLVSQSSSNASKLESLTRLVRLTKRDSSIRRKVTESGAVRAALDCVDSCNQVLQEKSLSLLLNLSLEDDNKVGLVADGVIRRIVTVLRVGSPDCKAIAATLLTSLAVVEVNKATIGSYPDAISALVSLLRVGNDRERKESATALYALCSFPDNRKRVVDCGSVPILVEAADSGLERAVEVLGLLVKCRGGREEMSKVSGFVEVLVNVLRNGNLKGIQYSLFILNCLCCCSGEIVDEVKREGVVEICFGFEDNESEKIRRNATILVHTLLGIPMSS
What is the function of this protein?
Functions as an E3 ubiquitin ligase (By similarity).  Involved in the age-dependent pseudo-self-compatibility process.
What are the official names of this protein?
U-box domain-containing protein 8, Plant U-box protein 8, RING-type E3 ubiquitin transferase PUB8.
Protein: YC58_SCHPO
Sequence: MTGLLSILLHYKGNGDLATTDIPSHEKIPSAKRTAVQFCIGPTHEQSPRMSTVSQGRVTFAVLPTKPKDEVTSMKANGSRQSSCIVSNARKRQSVHCLSRSPIPSTRLKENDSRLCSPLASPTGGLKRPAKVSFALANTPSRKGNLVPQSPRRTIATTCKGVLEDVLKKDNELKFNDSDEEDEVDDEEIESFNSFSRKMQTISNSRYRGSPKPNIEKQSCSSESDRVSQISDDEEDEEGSADEEDEEDSDVELSESSLSDDEDSPLRCPSTPVQTAAAPNESQIPDDTDFVPGTFDEDQPACLAFACSLTHANSKRSIMLPQDIDPTFPDSEPEDDGHASSTVGSLSKEEARFKAKAKWNYKSSFSAHVSSEVLRNSKSPPLDIARKAVGAHRV
What are the official names of this protein?
Uncharacterized protein C1259.08.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOBA_HISS2
Sequence: MATTISAVILAGGQAKRMAGLDKGLQLLQGKPLYQHCLQRLTNQVSSISINANRHQAIYQQSGVEVFGDELEDFQGPLSGILTALERANTDFVLFVPCDSPFLPLNLCEKLQSAVENSKSLLAYANDGEREHPAFSLLSTQLKLPLRVYLQSGHRQMLQFFRQHKAISVDFSLQKQAFVNMNTLQDIEKYQNIYA
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_SYNAS
Sequence: MKRAFERMSMAIAIRNQQKKVKIDLRQIRRRVQKLLRLVDCREKEISLLFVDDEEIQEINQRYLGRNYPTNVISFSLSEGEFSSVNPDVLGDIVISVDTASRDAERGNIPVSDELDFLIIHGLLHILGYNHENNNPEETACMQKKEQELFFLLHGYPLDF
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_CHLTE
Sequence: MKTGIKKVKLHVRKNDEVTVIAGNDKGKSGKVLKVFPQKGRVIVEGVNIRKRHMRPTQGMPQGAIIEREFPIHVSNVKKS
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: AZI2_HUMAN
Sequence: MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTSSPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSETAFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN
What is the function of this protein?
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity (PubMed:14560022, PubMed:21931631).  Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization (PubMed:14560022, PubMed:21931631).  Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1 (PubMed:14560022, PubMed:21931631).  Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B (PubMed:14560022, PubMed:21931631).  Participates in IFNB promoter activation via TICAM1 (PubMed:15611223).
What are the official names of this protein?
5-azacytidine-induced protein 2, NF-kappa-B-activating kinase-associated protein 1, Nak-associated protein 1, Nap1, TILP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIBC_VIBCH
Sequence: MVMKREVVGYTTMSEHLIDTQLTRSPFFFASANQSMLGCGVAHAFQQAIPFAELANQAKQLLQQAKRDECDNPLLFGIVPFDPKTPTRFMIPRTLYVSSSPRLNRPAHLTRQVAKLISSPSGEQYKQGVSHLLNMFHHSGLSKVVLSRAIEIATEQEIALPTLLRSLLAINHHGYTFAASLDEQRKLIGASPELLVAKRGNYLISNPLAGSRPRSQDAQENAQRRASLLNTAKDLHEHGLVVEEVERIMSRYCRNLYTPMVPSVIETETMLHLSTLLEGQVSDPEVCALQVAADLHPTPAVCGFPRESAYQAIRELEEFDRGYFTGMVGWCDARGNGEWVVTIRCAEVGSHQMKLFAGAGIVDESLPQSELEETGAKMKTILAAAGIELNDVLTA
What are the official names of this protein?
Vibriobactin-specific isochorismate synthase, Isochorismate mutase.
What is the protein family that this protein belongs to?
Belongs to the isochorismate synthase family.
Protein: DNLJ_HELPS
Sequence: MIKSQKEYLERIEYLNTLSHHYYNLDDSIVSDAVYDELYQELKAYEGKNPNSIQANSPTQKVGATTPNSFNKNPHLMRMWSLDDVFNQSELQAWLQRILKAYPSASFVCSPKLDGVSLNLLYQHGKLVKATTRGNGLEGELVSANAKHIANIPHAIAYNGEIEIRGEVIISKKDFDALNKERLNANEPLFANPRNAASGSLRQLDSEITKKRKLQFIPWGVGKHSLNFISFKECLDFIVSLGFSAIQYLSLNKNHQEIEENYHTLIKEREGFFALLDGMVIVVNELNIQKELGYTQKSPKFACAYKFPALEKHTKIVGIINQVGRSGAITPVAVLEPVEIAGAIITKATLHNYSEIEKKNIMLNDRVVVIRSGDVIPKIIKPLESYRDGSQHKIERPKVCPICSHELLCEEIFTYCQNLNCPARLKESLIHFASKDALNIQGLGDKVIEQLFEEKLIFNALDLYALKLEDLMRLDKFKIKKAQNLLDAIQKSKNPPLWRLINALGIEHIGKGASKTLARYGLNVLEKSEAEFLEMEGFGVEMARSLVNFYASNQEFIRSLFDLLNPKNSDMAEEKQESSSVFSNKTIVLTGTLSKPRQEYAQMLENLGAKISSSVSAKTDFLIVGENAGSKLALAKKHGVSVLNEEELLKRLKEFD
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: IF1_RICCN
Sequence: MSKDDLIQFTGTVLELLPNATFRVKLENDHVIIAHTSGRMRKNRIRILLGDKVMVEMTPYDLTKGRVIHRH
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEM1A_RAT
Sequence: MDLHTAVYNAAHDGKLLLLQKLLAGRGREEIEELLGEVAGGGTPLLIAARRGHLDVVEYLVDNCGASVEASGSVHFDGETIEGAPPLWAASAAGHLAVVRSLLRRGASVNRTTRTNSTPLRAACFDGHLDVVRYLVGEHKADLEVANRHGHTCLMISCYKGHREIARYLLERGAQVNRRSAKGNTALHDCAESGSLEILQLLLGCHARMERDGYGMTPLLAASVTGHTNIVEYLIQEQPGHGQLSGTELPGEGSSQMAGNHCSTPEEAEPYESCCPTSREAAVEALELLGATYVDKKRDLLGALKHWRRAMELRHQGGDYLPKPEPQQLVLAYDYSREVSTPQELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQNNLEPLSPMTASSFLSFAELFSYVLQDRSAKGNLGMQLGFADLMGVLSKGVREVERALQLPKEPGDSAQFTKAIAIILHLLYLLEKVECTPSQEHLKHQTVYRLLKCAPRGKNGFTPLHMAVDKETTNVGRYRVGIFPSLQVVKVLLDCGADPDSRDFDNNTPLHVAAQNNCPAIMDALIEAGAHMDATNAFKKTAYELLDSKLLAKSTMQPFNYVTLQCLAARALDRNKVPYKGFIPEELEAFIQLH
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.  The CRL2(FEM1A) complex specifically recognizes proteins with an arginine at the C-terminus: recognizes and binds proteins ending with -Lys/Arg-Xaa-Arg and -Lys/Arg-Xaa-Xaa-Arg C-degrons, such as SIL1 or OR51B2, leading to their ubiquitination and degradation (By similarity).  Involved in PGE2-EP4-mediated inhibition of inflammation of macrophages via interaction with NFKB1 and PTGER4.  Promotes inflammation in brain microglia through MAP2K4/MKK4-mediated signaling (By similarity).
What are the official names of this protein?
Protein fem-1 homolog A, FEM1a, FEM1-alpha.
What is the protein family that this protein belongs to?
Belongs to the fem-1 family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.