PharMolix/UniProtQA huggingface dataset:
Protein: COAD_HELPS
Sequence: MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAYSCAKNPMFSLKERLEMIQLATKGFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIHPFISKV
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_RENSM
Sequence: MPENFGAMRQDGLVSTSESDSPAPAATPAATLRAEYSKLVEDIRHYRFAYYNEAESLVSDAEFDVLFRRLEEIEALHPELISNDSPTQEVGGEVSAAFTPVQHTSQIYSLEDVFSIEELQSWIIKAQANAEKLAGSIVAERPLRWLTELKIDGLAVNLLYRNGQLVRAATRGDGITGEDITHNVLTIQEIPRQLRGENLPEEVEIRGEVFIASKDFLALNEQIVGTGRAPFANPRNAAAGSLRQKDPADTAKRPLSMLVHGIGSRIGLDVASQSESYALLKAWGLPTSPYFKVLTGYQEVLDYINHYGEHRHDLLHEIDGIVIKIDDFASQNALGFTSRVPRWAVAYKYPPEEVHTKLLDILVNVGRTGRVTPFGVMEPVKVAGSTVEMATLHNQDVVKAKGVLIGDTVVLRKAGDVIPEIVGPVLALRDGREREFVMPTECPSCGTALAPAKEGDVDIRCPNAKSCPDQLRERVFHLAGRGAFDIEALGWEAAIALTQPAEPELAPVRNEAQIFNLVAEDLALVKIKREKKVKGVLSGVHELVPYFYSKGTEEKPSEPTSNTVKLFIELEKAKAQPLWRVLVALSIRHVGPTASRALATAFGSMAAIRAASEPELAEVDGVGPTIAAALIEWFAEDWHREIIDAWAADGVRMADERDESVRRTLAGLTIVVTGSLEKFNRDQAKEAIINRGGKSAGSVSKNTDYVVAGENAGTKLDKAEKLGVTVLDEAGFETLLAHGPDHSAEAEENESEGSTTND
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: FACE2_DROME
Sequence: MKNLSETEAEVTMQENVVHESLPQIPVATSVSCCFVLAVLYVGSLYIWSTKHNRDHPTTVKRRFASVSMVMLAAPFFVYFFSSPELLSRVPFPKLLGLRLEGLWQAVVIPYSLTVLLFLGPIFVNMQNESVRSYFDLDYWRGSFGSIIWVRNHVIAPLSEEFVFRACMMPLILQSFSPLVAVFITPLFFGVAHLHHIAERLSLGVELSTALLIGLFQFIYTTLFGFYSAFLFARTGHVMAPILVHAFCNHMGLPDLQDLWQQDLWRRVVAIILYLAGFVGWMFLVPLATDPSIYDNTLYWNA
What is the function of this protein?
Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins.
What are the official names of this protein?
CAAX prenyl protease 2, Farnesylated proteins-converting enzyme 2, FACE-2, Prenyl protein-specific endoprotease 2, Protein severas.
What is the protein family that this protein belongs to?
Belongs to the peptidase U48 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: U17PA_MOUSE
Sequence: MVVALSFPEADPALSSPDAPELHQDEAQVVEELTVNGKHSLSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKLCAMEALVTQSLLHSHSGDVMKPSHILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSKPTSEDSSPIHDIFGGWWRSQIKCLLCQGTSDTYDRFLDIPLDISSAQSVKQALWDTEKSEELCGDNAYYCGKCRQKMPASKTLHVHIAPKVLMVVLNRFSAFTGNKLDRKVSYPEFLDLKPYLSEPTGGPLPYALYAVLVHDGATSHSGHYFCCVKAGHGKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQANLKQVSIDMPEGRINEVLDPEYQLKKSRRKKHKKKSPFTEDLGEPCENRDKRAIKETSLGKGKVLQEVNHKKAGQKHGNTKLMPQKQNHQKAGQNLRNTEVELDLPADAIVIHQPRSTANWGRDSPDKENQPLHNADRLLTSQGPVNTWQLCRQEGRRRSKKGQNKNKQGQRLLLVC
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.  Has deubiquitinating enzyme activity for DNAH5, suggesting a role in the regulation of DNAH5 degradation by the ubiquitin-proteasome pathway.  Has growth-suppressing activity; induces arrest in G1 phase upon controlled expression.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 17-like protein A, USP17-A, Deubiquitinating enzyme 1, Ubiquitin carboxyl-terminal hydrolase DUB-1, Ubiquitin thioesterase DUB-1, Ubiquitin-specific-processing protease DUB-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: MIAA_CYAP4
Sequence: MELFLNLESRPGLIVICGPTATGKSGLAIALAEYLNTVILSADSRQVYKEFDIGTAKPTVQERQQVAHYLIDICEPTDNCTLAQYQEQANQLIQHFHQQGKTPLLVGGTGLYIQAVTEGLIIPRVAPQVELRSQLAQLAQTQLYAYLQQVDPVSAQRIHANDQVRTLRALEVYYVTGIPLSQQQGRNPPSYPICKIGLESEQLTHRIQQRTLQMLEKGWLAEVEFLLKQYGDDLPLLKTLGYAEMKQHIAGETSLEEAIQLTVLHTRQFAKRQRTWFRADAEITWLNGDDAQLLEKLQPG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TRPA_XYLFM
Sequence: MHRIDETFRRLRAQSRKALIPFITAGDPSLEAAVPVMHALVRAGADVIELGVPFSDPMADGPVIQHSSERALQRGVGLAYVLQTVDVFRQSDAVTPVVLMGYLNPLEIYGIARFTQQALASGVDGVLLVDLPPEEADEIRAIFSAAGLALIVLASPTTSASRLATLSGVAQGYLYYVSFAGVTGADRLDAQSAGDRLRGLRAQTQVPVVVGFGIRDAASAVVMAVDADGVVVGSALVTALSDAPDVDTACRRADAFLAPLRQALDAVK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: VME1_BCRP3
Sequence: MAENGTISVEELKRLLEQWNLVIGFIFLAWIMLLQFAYSNRNRFLYIIKLVFLWLLWPVTLACFVLAAVYRINWVTGGIAIAMACIVGLMWLSYFVASFRLFARTRSMWSFNPETNILLNVPLRGTILTRPLMESELVIGAVIIRGHLRMAGHSLGRCDIKDLPKEITVATSRTLSYYKLGASQRVGTDSGFAAYNRYRIGNYKLNTDHSGSNDNIALLVQ
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: KCY_MYCA1
Sequence: MSADVVVAIDGPAGTGKSSVSKGLARALGARYLDTGGMYRMVTLAVLRAGIDPADADAVGRAAQAVRMSVDYHPDGDRYFLGGEDVSTEIRGDKVTAAVSAVSSIPAVRTRLVGLQREMASGPGSIVVEGRDIGTVVLPDAPVKIFLTASAETRARRRNDQNVAAGLADDYEAVLAEVRRRDHLDSTRRVSPLRAAPDAVVVDTSDMTEAQVIDHLRDLVRQRSEVAR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y728_ENT38
Sequence: MEIYCELIRKRYAEIASGDLGYIPDALGCVLKVLNEVATDNSLSESIREKAAYAAANLLVSDYVNE
What are the official names of this protein?
UPF0253 protein Ent638_0728.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: YIHI_SALPC
Sequence: MKKPTSAPRSKAFGKQRRKTREELNQEARDRKRLKKHRGHAPGSRAAGGNSASGGGNQNQQKDPRIGSKTPVPLGVTEKVTQQHKPKSEKPMLSPQAELDLLETDERLDALLERLEAGETLSAEDQAWVDAKLDRIDELMQKLGLSYDDDDEDDEEDEKQEDMMRLLRGGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: YKNY_BACSU
Sequence: MIQLSNVRKSYQIGKETFDVLHSIDLDIHQGEYVSIMGPSGSGKSTIMNIIGCLDRPTSGTYQLDGEDISSYKDKELAAVRNRSIGFVFQQFQLLPRLNAKKNVELPMIYSGIGKKERQERAERALEKVGLADRMLHMPNELSGGQKQRVAIARAIVNEPKLILADEPTGALDTKTSEAIMDQFTALNAEGTTIVLVTHEPEVADCTNRIVMVRDGNIVPASSGQRSVGE
What is the function of this protein?
Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation-delaying protein).
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YknY.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1235_STRP2
Sequence: MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDSYKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK
What are the official names of this protein?
UPF0223 protein SPD_1235.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: PSB_ACIC1
Sequence: MTTSGGLTGPGAFGRLPQPFHQPGITSFVEFLALQAPDLLPGRLQMPAGGQPPEVPHGTTIVAVAYQGGVVMAGDRRATMGNVIAQRDIEKVFQTDEHSCVGIAGSAGIALEVVRLFQVELEHYEKLQGTTLSLEGKANRLAMMIRANLPMALQGLAVVPLFAGYDLFADDPQRAGRIFSFDVTGGRYEEHSFHAVGSGSTFARGALKKLFRDDFDEPHAVRTCIEALYDAADDDSATGGPDLTRRIYPVVAVVDANGFRRLADDTVGGVVEQVIAARMANPGGPVAVLP
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1880_VIBVU
Sequence: MRKRIWVGLPLALVFGGIFAFHTVFHIPEQPEMTTISDGSFNQQLHCYESSTRASIDQEGSLNLLVWNIYKQNRANWQSVLTQMSAGAQLILLQEASLEDGLKRWIASGGWSGEQVNAFKAFDKAAGVLTLGWRKPRLACGYTQLEPWIRLPKSGLYSEYLLSDGQMLIVVNLHAVNFTWGVQEYQQQVNDLIAALKEHPGPAIVAGDFNTWSEKRLQAVTERLENAGLIEVVFSPDQRTRFITGLPLDHVFYKGLEVQKAEAPQTDASDHNPLLVSFTLPTDK
What are the official names of this protein?
UPF0294 protein VV1_1880.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_RHOP2
Sequence: MFGRRSMADPPAPPAIILAGGLAQRMGGGDKALRMVGGRTLLALVIDRLASQCDILALSANGDPARFADYDLPVIADPVDGFRGPLAGVLAGLDWVAEHRPAARWMLSTPADCPFLPRDLVARLHQARIDQQADIAVAASAGRSHPVIALWPVGLRIDLRRALLADDIRKVDRFTARYPRAMAEWPVEPADPFFNANTPQDLAEAEGLAMREPD
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_STAES
Sequence: MAEQRWTGQLDLTVFNNGQSSKARNIFFEKALKVLRPIYLEQSPVPTFYIVNVGGGYLDGDRYRVNVNLEDNAQVTLTSQGATKIYKTPNDHVEQYQTFNLSNQSYMEFVADPIIAYENAKFFQHNTFNLKEDSAMFYTDILTPGYSSNGQDFTYNYMHLINEIYIDNQLVVFDNMMLSPDKSRLDGIGYMENYTHLGSAYFIHPDVNQSFIDDIYAAVADFQKQYDCRIGISQLPTHGLAVRILTKRTQIIEEILTRVQSYINQTIYHRQINFLRKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_CMVCS
Sequence: MDKSESTSAGRNRRRRPRRGSRSAPSSADANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCKPGYTFTSITLKPPKIDRGSYYGKRLLLPDSVTEYDKKLVSRIQIRVNPLRKFDSTVWVTVRKVPASSDLSVAAISAMFADGASPVLVYQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDALETDELVLHVDVEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: TRUA_SHIBS
Sequence: MSDQQQLPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAPRKDAAWTLGVNANLPDDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MSRA_SALPC
Sequence: MSLFDKKHLVTQADALPGRNTPMPIATLHAVNEHSMTNVPAGMEIAYFAMGCFWGVERLFWQLPGVYSTAAGYAGGYTPNPTYREVCSGQTGHAEAVRIVYDPAVIRYEQLLQTFWENHDPTQGMQQGNDHGTQYRSAIYPLTPEQNAAAHASRERFQSAMAAAGDHRPITTEIAHATPFYYAEDEHQQYLHKNPYGYCGIGGIGVCLPPDA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: SSRP_DESPS
Sequence: MGIKIVCKNKKAYHEYEILDTYEAGMVLSGPEVKSLRGGRGNLVDGHVAINARGEAMLYNVHISHYMFTSHNPVEPLRVRKLLLHKRELHKLNGKLKEKGLALIPLKIYFIENGKAKIELGLAKGKKMYDKRATLKEQQGKRELARVMRRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GACY_DICDI
Sequence: MDSSFKRASFKLPPGVNIDNINEMNNNNMNTAPAPAPAPIPTPQPTTTTTTAPQRKVTFGSRVRAQEINATPTPTTPAPAPTTTPSENDTAKKDDFDFDPVPVSRPRATRAATMIPSNMLGDKRPIRPLGKGFIGADRQTPKPETDNNNNGNNNNNNNNNDNNNNNNNNDDDDEDEDDDEYSNVSAPSWNSVLSKAKTNTMNSRKRSGMIHDFVDVNIKNDSGGENSANTTSEDGSSSRRGTLRKAIVIGTHNPQPQQEDDVEETTSRISSLDLANVQRPRPQYHTIDPASIPQWKKNNEDLVNTMEQQQQQPQQPQQPQQQQSTVGGLFNSILKKQPNNNANNAQRLTRAEAEYNEYLTKSKSQRFPEIEALNFIYPAGKDNLGRTIIVIIASHLPVREMDMERVLLYTISIMDPVVEEEYVLVYVHTNMNNSNKPSMAWMKKVYTIFNRKYKKNLKGLYIVHPTTWIKFTLGIFKHFLSSKFWKKLTYIDDLGELFKTFPREQLALPNAIMMHRPAGKKSQPIFGAPLEDVINRPDNPGEIPVLFEKGIAYLSRRGLQVEGLFRLSGANSQIKSLRQGFDQGEDVDLEDVEDVHTVAGLLKLYLRELPSPLFPFDLYSSFIEISKGEQTKPQKVESLKLLLSLLPPANKALSKHLFKFLGKVIENSSVNKMNSVNLSIVFAPNLLKDKEGNVMDAVADAQFVNQVVQLILDNINILFNY
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacY, GTPase activating factor for raC protein Y.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_HYDCU
Sequence: MPDIACQPHQDPQGKLNWVGMSGIELPIKIEQDSQTLTLSSQVQAYVSLDDPLSKGIHMSRLYLILDEMGSNAPLNPASIQTLLTAFIESHQGLSQNAFVEFRFDYYERRRSLKSDNSGWKHYPCTLRGEMRNGQFECEISISVPYSSTCPCSAALSRQLIQEAFEQQFNGQDLDYNQVLEWLGTPEGICATPHSQRSYAQVKLKVNAEHPLNLSNVINQIEDAVKTPVQSTVKREDEQEFARLNATNLMFCEDAARRLQAKLESCPEYKDYWVRVNHLESLHPHDAVAIVTKNVPGGYSDEPNFMERFQN
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: PAN3_SCHPO
Sequence: MSVRKNSPASPKPTSRSRESSRSPSVTDLKDHSKAKRTLCRNILLYGSCKHSENGCAFRHDGPFIPSSENLEQYSVKKKLNAASASFQPVRALPVKAAGAAVFVPKSQEKSLFLSRERTPVALSPGSHAINPYNNASMLVNEPFHDDSGVYYTRQNQFKPTLYNLYNPQPSPMPTLLPYERTVNGLFIDDTTRERIERKSEASRQTISALPSIISSYTSLAPLNTKLYRYKEQIGFSSWTYKCTSSIDGNAYVLKRLQDCSINIDTSTVDKLKNVFHPNIVPFHSAFHTDTFHDSSLLLIYDFYPCTTTLGELYLNNSKNSVKLEENRKIPERELWNYFFQLTIALSYLHKSGFACNKLTPSRILVDQTERIRISGCADYELVVSNKPPLEERKKQDFVDLGVVIANLATGRTDMDMSSAARAIYSTYSREFYKAVLYFVSEVPEDKNLELFLQNHIESFFPIMSSPYVECEKMERKISDAFQHGRFFNILCKIMFIIDNNRASREYPIAREKEISLIYLLRDYLFHQIDEDECPVIDLYQVLNRLGKLDAGINQAIALISRDELDCVSVSYGELKAWLDNVYEMEINS
What is the function of this protein?
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.  ppk26/pan3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit pan2 to mRNA via its interaction with RNA and with pab1.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex subunit pan3, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. PAN3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EPSH_METS1
Sequence: MEKHIKHAIRWPSLDTIPWAWVAIAIGLLILYFPTFWDLFHGLWGTERHAHGPIVFFVSIWFFYFKFKQLPEYGITYDPSPKLGWPILVLGLLLFILGRSQTLLIFEVGSLIPVLLGITLIFMGTRVAKFLWFAFFFLCFVVPLPAFVVDAATLPMKTAVSFATAHILYALDYPIARTGVMLTIGQYQLLVADACAGLNSLFTLEVLGLLYMNVTHHESPFRNFMLAVLIIPISFIANVTRVIVLALITYHWGDAAGQGFLHEFSGIVLFITALMLVIATDSLLRFFSRKFEKVPSTQSVDLKR
What is the function of this protein?
Transpeptidase that recognizes and modifies its substrate by proteolytic cleavage of a sorting signal.  Following cleavage, a covalent intermediate is formed via a thioester bond between the exosortase and its substrate, which is then transferred and covalently attached to the cell membrane (By similarity).  This sortase may recognize a tripartite structure consisting of a conserved Pro-Glu-Pro (PEP) motif, followed by a transmembrane alpha helix domain and a cluster of basic residues, usually at the C-terminus of target proteins (Probable).
What are the official names of this protein?
Probable exosortase EpsH.
What is the protein family that this protein belongs to?
Belongs to the exosortase/archaeosortase family. Exosortase EpsH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CC142_HUMAN
Sequence: MAQASRSGSLPPLVIVPPLRAQPGGTGEEQWERSRTGGLRWEVHCWPSGTSGGTPWWPTPADVSEDYEADAAAWRRGPAGGGPIPPALQRLRAVLLRLHREREQLLQARDCAYHLQSAVRLMKTLSPGSPSGGPSPLPQWCRDLQLHPSQGAVLRIGPGETLEPLLLARPIGLAAQCLEAVIEMQLRALGREPASPGLSSQLAELLFALPAYHTLQRKALSHVPGAARPFPTSRVLRLLTGERGCQVASRLDEALQGSALRDQLRRRCQEEGDLLPGLLGLVGGVAGSASCGLGLGGAGALWSQYWTLLWAACAQSLDLNLGPWRDPRATAQQLSQALGQASLPQECEKELASLCHRLLHQSLIWSWDQGFCQALGSALGGQSSLPTSSGTAELLQQLFPPLLDALREPRLRRIFCQPADPAPVALGLCTLQTTLLWFLGRAQQYLAAWDPASFLLLIQKDLPPLLHEAEALYSLASEESLALEVEQQLGLEIQKLTAQIQLLPEESLSVFSQECHKQAMQGFKLYMPRGRYWRLRLCPEPPSAPSEYAGLVVRTVLEPVLQGLQGLPPQAQAPALGQALTAIVGAWLDHILTHGIRFSLQGALQLKQDFGVVRELLEEEQWSLSPDLRQTLLMLSIFQQLDGALLCLLQQPLPKSQVHRRPPCCCACQEVQTTKLPSSCLNSLESLEPPLQPGTSPAQTGQLQSTLGGRGPSPEGYLVGNQQAWLALRQHQRPRWHLPFFSCLGTSPES
What are the official names of this protein?
Coiled-coil domain-containing protein 142.
Protein: Y3343_XANAC
Sequence: MRIEVWQGDITELDVDVIVNAANESLLGGGGVDGAIHRAAGPRLLEACEALPQVRPGVRCPTGEIRITDGFDLKARHIFHTVGPVWRDGRHNEPEQLANCYWQSLKLAEQMMLHSIAFPAISCGIYGYPLHQAARIAVTETRDWQRSHKVPKHIVLVAYNEATYKAYQQALATQETAAA
What are the official names of this protein?
Macro domain-containing protein XAC3343.
Protein: SURA_CUPPJ
Sequence: MKRQEFALFSLTLMLSPWRRVLLPAVLAAMAGPALAQLKAPSQASRATGIFVPQSSDVAVPSSQPQLGVPQPSSGGKRSQLVDEVVAVVNNSVITRRELLDRADEIEAQLRTANRPAPPRADLLGEVLERLIMERVQTQAAQDAGIKVTDQELDRAIESVAQQNRLSATELRRRVEASGMTWTKYRDELRKQVQVIRLREREVDSKVQVYDGEIDNYLAARGGQGAAATGPTEFNVSQILVRVPENASDAQKQELQKKAEQLLKQAQGGADFAQLAQANSQGPEAAQGGAIGFREIGRLPALFANAVVDLQPGAVAPEVVESANGFHILKLTAKRVAPASTSASSPAAASRITQTQVRHILIRTGPNMPEAEARRQLGTLRDRITHGGDFADAAKRFSQDGSAQAGGELGWVSPGELVPEFEQAMNRLRPGEISEPVVTQFGVHLIQVENRRETEMAPEKQRDFARAEIREQKLRAAYDDWVRQLRSQAYVEYRVNRQR
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: THIQ_BRUA2
Sequence: MTASADIRLSDVRFSYGETAMHFDVTITGGEIAAIVGPSGSGKSTFLNLIAGFETPQSGIISINGVDVTHLPLADRPVSMVFQENNLFAHLTVEQNVDLGRSPNLRLNEEDRKAVASALARVGLQGKEKRKPEALSGGERQRVAIARVLVRERPVLLLDEAFASLGPALRHQMLDLVNKLRRETGMTVLMVTHTPEDALHLDALLIFLDNGKIAAQGPATEMLSRAGPEALRHYIGEMRSF
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUSB_ACTP2
Sequence: MKVSPRRRARECAVQALYSWYVSQNSVEEVELSFVTDQDMNGVDLPYFRKLLRGTVLYVEAIDNDLRPFLDRAEDEVDPIERTILRLSAYELKYELDVPYKVVINEGIEVAKVFGSDDSHKYINGILDKLAPALGRK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: APEA_BORBU
Sequence: MKKQNPWIYLNEEEKNQILNFSESYKKFISKFKTEREVTAYALDKAKKLGFINAEEKKNLMPGDKIFYTCREKSVAFAIIGKNPIEDGMNFIVSHTDSPRLDAKPSPISEENELTFIKTNYYGGIKKYQWLSTPLSIRGVVFLKNGEKVEINIGDNENDPVFVIPDILPHLDRKIQRNKKSDEIVEGENLKILIGSLPIETKEKNKVKLATLQLIKEKYKIEEEDFVSSEIEIVPAGTAKDVGFDKALIGAYGQDDKICVFTSLESIFDLEETPNKTAICFLVDKEEIGSTGSTGLDSRYLEYFVSDMIFKIKKSEYNNLHVQKALWNSKSISADVCAAINPLFSSVHDEQNAPQLGYGIPIMKYTGHGGKSMASDADAELVSYIRQLLNKNNIAWQVATLGKVEEGGGGTVAKFLAGYGIRTIDMGPAVISMHSPMEITSKFDLYNAYLAYKAFYRE
What are the official names of this protein?
Probable M18 family aminopeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.