PharMolix/UniProtQA huggingface dataset:
Protein: NOS_SQUAC
Sequence: LNYQLSPSFEYQSDPWFTHVWKGVNGTPTKKRAIGFKKLAKAVKFSTKLMGQAMAKRVKATILYATETGKSQVYAKTLCEIFKHAFDAKVMSMDEYDIVHLEHEALVLVVTSTFGNGDPPENGEKFGSALMEIRHPSSNSAERKSYKVRFNSVSSYSDSRKSSSDEPEHKDNFESTGPLANVRFSAFGLGSRAYPHFCAFARAVDTLLEELG
What is the function of this protein?
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
What are the official names of this protein?
Nitric oxide synthase, NOS.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
Protein: ATPL_GEOSE
Sequence: MSLGVLAAAIAVGLGALGAGIANGLIVSRTIEGIARQPELRPVLQTTMFIGVALVEALPIIGVVFSFIYLGR
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: QUEC_HALH5
Sequence: MENKKKKAVVVFSGGQDSTTCLFWALKTFDEVATVTFDYGQRHAEEIECAKEIAEQLGVSFRVLDMTLLNQLTESALTREEIAVKDGENGELPSTFVPGRNQLFLSFAAVYAKQIGARHLVTGVCETDYSGYPDCRDVFIKSLNVTLNLAMDDQFVIHTPLMWLDKAETWKLADELGALDFVREKTLTCYHGIRGDGCGECPACMLRRRGLELYLAEKEGDRA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PNP_STRP4
Sequence: MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAVMSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFAEGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQIIINPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQEEIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVTAVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVVDFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGETGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGTLALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITALQMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVDKIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKVDEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKIDEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHHY_ACIAD
Sequence: MQTMKTKVAIIGSGPAGLLLGQLLYKAGIEHVIVEQRSADYVASRIRAGILEQVSVDLLEQAGVDQNLKEKGLPHSGIEILTNGQKFRVDLSALTQGKQVTVYGQTEVTKDLMQAREQAGLCSFYESNDVQIHDFYNAPKVTFESNGTHYQIECDFIAGCDGYHGVCRASVPQDKIKTFEKVYPFGWLGVLADVPPVADELIYVQSERGFALCSMRSETRSRYYIQVPLTDHVENWSDDQFWEELKNRLDPESCEKLVTGPSIEKSIAPLRSFVTEPMRFGKLFLAGDAAHIVPPTGAKGLNLAASDIAYLSSALIEFYTQGSEQGIDQYSEKCLQRVWKAERFSWWMTHLLHRFETESEFDHKIKQAELSYILGSTAGQTTLAENYVGLPYEIKSLDYLKHAS
What is the function of this protein?
Catalyzes the incorporation of an atom of dioxygen into p-hydroxybenzoate (p-OHB) to form 3,4-dihydroxybenzoate (3,4DOHB).  The reaction occurs in two parts: reduction of the flavin adenine dinucleotide (FAD) in the enzyme by reduced nicotinamide adenine dinucleotide phosphate (NADPH) in response to binding p-hydroxybenzoate to the enzyme and oxidation of reduced FAD with oxygen to form a hydroperoxide, which then oxygenates p-hydroxybenzoate.
What are the official names of this protein?
p-hydroxybenzoate hydroxylase, PHBH, 4-hydroxybenzoate 3-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family.
Protein: A1MA3_LOXDE
Sequence: WIMGHMVNAIAQIDEFVNLGANSIETDVSFDKNANPEYTYHGIPCDCGRTCTKSEKFNVFLQGLQKATTPGDSKYQEKLVLVVFDLKSSSLYDNQASDAGKKLAKSLLQNYWKNGNNGGRAYIVLSIPNLAHYKLITGFKETLKTEGHPELMEKVGYDFSGNDDIDQVAKAYKKAGVTGHVWQSDGITNCLPRGLDRVKQAVANRDSSNGFINKVYYWTVDKRSTTRGALDAGVDGIMANYPDVIADVLSESAYKSKFRIATYEDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LdSicTox-alphaIB3aiii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS6_SHESA
Sequence: MLAKRIVPCLDVKDGCVVKGVQFRNHEIVGDIVPLAARYAAEGADELVFYDITASAHDRVVDKSWVSRVAEQIDIPFCVAGGIKTIGQARELLAFGADKISVNSPALSDPSLISRLQDEFGRQCIVIGIDSFYDAASDSYKVKQFTGDEAATKETAWYTQDWVEEVQKRGCGEIVLNVMNQDGVRGGYDIKQLSLVRQLCDVPLIASGGAGTMTHFRDVFIEAKVDAALAASVFHKAIINIGELKQYLAAEGIAIRQ
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGW2_SCHPO
Sequence: MTLLDSSIFRFRLSSLHVSSRSLGVYFAGIMFASAVWVFVDAALYSAFDYARNLHITFIDWIPFLCSILGIVIVNSIDKSRLSGDSFAYTDESLARKARFILFIGFALLAGGLGGSFTVFILKYVVAGYEGKSLLMGSANIISNILFMISATALWITGNMNDDYHYNLQL
What are the official names of this protein?
UPF0220 protein C8D2.02c.
What is the protein family that this protein belongs to?
Belongs to the UPF0220 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AGP24_ARATH
Sequence: MMMMTKMFVQIAVVCLLATMAVVSAHEGHHHHAPAPAPGPASSSTVVSATNMFTVLAIAAVALVVGSNH
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.
What are the official names of this protein?
Arabinogalactan protein 24, AtAGP24, Arabinogalactan peptide 24, AG-peptide 24.
What is the protein family that this protein belongs to?
Belongs to the AG-peptide AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CSRA_SALNS
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: HCS1_USTMA
Sequence: MSARPQNVGIKAIEIYFPRRCISEDELEDFDGVAKGKYTIGFGQKYMACTDDREDINSFALSVVSGLLEKNNIDPRSIGRLDVGTETIIDKSKSVKTVLMDLFAPSGNMNIEGIDSKNACYGGTAALFNAINWVESSSWDGRDAIVVAGDIAIYAEGSARPVGGAGSVAMLIGPDAPLVFEPAHGTHMSNYWDFYKPNLSSEYPEVDGPETIQTYLGCLDKAYDAYRLRAAKLKSGAANGHSDASSLASIKVDDFDYTLFHSPYSKLVQKGFGRLLYNDFFSDPKNEKYASIPANFAELDRKSTITNKDVEKAFAAFGKEAQQTKLEPGMNTVRRCGNMYTASLYGGLVSLLSNIPSQEIQGKRILLYSFGSGAAASMFAIRINGSTEQIVKAVDLKNRLDSMKVVPCQTYVEALKTREATHNAVNHKPVGQLENLWPGAYYLENVDHMYRRTYGRIPTNAN
What is the function of this protein?
Hydroxymethylglutaryl-CoA synthase involved in the biosynthesis of siderophore ferrichrome A which is contributing to organismal virulence (PubMed:20070524).  The first step of ferrichrome A biosynthesis is performed by the HMG-CoA synthase hcs1 which catalyzes the generation of HMG-CoA and CoA using acetoacetyl-CoA and acetyl-CoA as substrates (PubMed:20070524).  The enoyl-CoA isomerase/hydratase fer4 then catalyzes the conversion of hcs1-produced HMG-CoA to methylglutaconyl-CoA (PubMed:20070524).  The acyltransferase fer5 then fuses the fer4-generated methylglutaconyl-CoA with sid1-generated hydroxyornithine to yield methylglutaconyl hydroxyornithine (PubMed:20070524).  Methylglutaconyl hydroxyornithine is then available for use by the NRPS fer3 to generate ferrichrome A (PubMed:20070524).
What are the official names of this protein?
Hydroxymethylglutaryl-CoA synthase, HMG-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
Protein: MIEAP_MOUSE
Sequence: MAESLKKLAKSESLQALQDKVTYWVNDYNSNSCDQNLNYCIELIEQVAKVQAQLFGILTVTAQEGGNNEGVETIKCRLLPLLQTSFSSVNMGKTAESEMCATQDFQLRSKNRDNSPDQDQHQSDNESFSETQPTQVQDDLAESGKSLEGAKNGSTISLLAAEEEINQLKKQLKSLQAQEDARHKTSENRRSEALKSDHRSTKRTQDQRPQDVVSNYEKHLQNLKEEIAVLSAEKSGLQGRSARSPSPSTGTRSHRRGRSRSHSRSRSHSRSNSPCTTVAKIRSPSPNRAKMSSVARKAALLSRFSDAYSQARLDAQCLLRRCIDRAETVQRIIYIATVEAFHVAKMAFRHFKIRVRKMLTPSNVGSNTDFETAVSEYIVCHLDLYDSQSSVNDVIRAMNVNPKISFPPEVDFCLLTDFIQEICCIAFAMQSLEPPLDIAFGADGEIFNDCKYRRSYDSDFTAPLVFYHVWPALMENDCVIMKGEAVTKRGAFWSSVRPVMRCRSRSLSPICPRNHFGISTVSRSRSPSPIRCTFARY
What is the function of this protein?
Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage.  Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen.  Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade unhealthy mitochondria by accumulating lysosomes.  May have a role in spermatogenesis, especially in cell differentiation from late elongate spermatids to mature spermatozoa (By similarity).  The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity).
What are the official names of this protein?
Mitochondria-eating protein, Spermatogenesis-associated protein 18.
What is the protein family that this protein belongs to?
Belongs to the MIEAP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane. Note=Localizes to the cytoplasm under normal conditions. Relocalizes to mitochondrion outer membrane following cellular stress. Colocalizes with BNIP3 and BNIP3L at the mitochondrion outer membrane.
Protein: MFAP2_MOUSE
Sequence: MRAACLFLLFMPGLLAQGQYDLDPLPPFPDHVQYNHYGDQIDNADYYDYQEVSPRTPEEQFQSQQQVQQEVIPAPTPEPAAAGDLETEPTEPGPLDCREEQYPCTRLYSIHKPCKQCLNEVCFYSLRRVYVVNKEICVRTVCAHEELLRADLCRDKFSKCGVMAVSGLCQSVAASCARSCGGC
What is the function of this protein?
Component of the elastin-associated microfibrils.
What are the official names of this protein?
Microfibrillar-associated protein 2, MFAP-2, Microfibril-associated glycoprotein 1, MAGP, MAGP-1.
What is the protein family that this protein belongs to?
Belongs to the MFAP family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: TRMA_KLEP3
Sequence: MTPEHLPTEQYEAQLAEKVVRLQTMMAPFAAPVPEVFRSPVSHYRMRAEFRLWHDGDDLYHIIFDQQTRSRIRVDSFPAASALINQLMTAMLEGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDTWREQAEALRDALRAQGLNVHLIGRATKTKIELDQDYIDERLPVGGREMIYRQVENSFTQPNAAMNIQMLEWALDVTKEATGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLQSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCRNLETLSQTHNVTRLALFDQFPYTHHMECGVLLTRK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RDRP_PVXX3
Sequence: MAKVREVYQSFTDSTTKTLIQDEAYRNIRPIMEKHKLANPYAQTVEAANDLEGFGIATNPYSIELHTHAAAKTIENKLLEVLGSILPQEPVTFMFLKPRKLNYMRRNPRIKDIFHNVAIEPRDVARYPKETIIDKLTEITTETAYISDTLHFLDPSYIVETFQNCPKLQTLYATLVLPVEAAFKMESTHPNIYSLKYFGDGFQYIPGNHGGGAYHHEFAHLQWLKVGKIKWRDPKDSFLGHLNYTTEQVEMHTVTVQLQESFAANHLYCIRRGDLLTPEVRTFGQPDRYVIPPQIFLPKVHNCKKPILKKTMMQLFLYVRTVKVAKNCDIFAKVRQLIKSSDLDKYSAVELVYLVSYMEFLADLQATTCFSDTLSGGLLTKTLAPVRAWIQEKKMQLFGLEDYAKLVKAVDFHPVDFSFKVETWDFRFHPLQAWKAFRPREVSDVEEMESLFSDGDLLDCFTRMPAYAVNAEEDLATIRKTPEMDVGQEVKEPAGDRNQYSNPAETFLNKLHRKHSREVKHQAVKKAKRLAEIQESMRAEGEAEPNETSGGMGAIPSNAELPGTSDARQELTLPTTKPVPARWEDASFTDSSVEEEQVRLLGEEAVKTATQQVIEGLPWKHWIPQLNAVGFKALLIQRDRSGTMIMPITEMVSGLEKEDFPEGTPKELARELLVMNRSPATIPLDLLRARDYGSDVKNKRIGAITKTQATSWGEYLTGKIESLTERKVATCVIHGAGGSGKSHAIQKALREIGKGSDITVVLPTNELRLDWSKKVPNTEPYMFKTYEKALIGGTGSIVIFDDYSKLPPGYIEALVCFYSKIKLIILTGDSRQSVYHETAEDASIRHLGPATEYFSKYCRYYLNATHRNKKDLANMLGVYSERTGVTEISMSAEFLEGIPTLVPSDEKRKLYMGTGRNDTFTYAGCQGLTKPKVQIVLDHNTQVCSANVMYTALSRATDRIHFVNTSANSSAFWEKLDSTPYLKTFLSVVREQALREYEPAEAEPIQEPEPQTHMCVENEESVLEEYKEELLEKFDREIHSESHGHSNCVQTEDTTIQLFSHQQAKDETLLWATIDARLKTSNQEANFREFLSKKDIGDVLFLNYQKAMGLPKERIPFSQEVWEACAHEVQSKYLSKSKCNLINGTVRQSPDFDENKIMVFLKSQWVTKVEKLGLPKIKPGQTIAAFYQQTVMLFGTMARYMRWFRQAFQPKEVFINCETTPEDMSVWALNNWNFSRPSLANDYTAFDQSQDGAMLQFEVLKAKHHCIPEEIIQAYIDIKTNAQIFLGTLSIMRLTGEGPTFDANTECNIAYTHTKFDIPAGTAQVYAGDDSALDCVPEVKHSFHRLEDKLLLKSKPVITQQKKGSWPEFCGWLITPKGVMKDPIKLHVSLKLAEAKGELKKCQDSYEIDLSYAYDHKDSLHDLFDEKQCQAHTLTCRTLIKSGRGTVSLPRLRNFL
What is the function of this protein?
RNA replication.  The central part of this protein possibly functions as an ATP-binding helicase (Probable).
What are the official names of this protein?
RNA replication protein, 165 kDa protein, ORF1 protein.
What is the protein family that this protein belongs to?
Belongs to the potexvirus/carlavirus RNA replication protein family.
Protein: RL31_ALKMQ
Sequence: MKKDIHPAYQQIDVHCVCGNKFKTGSTNKEIRVEVCSDCHPFYTGKQKSVEKGGRVEKFKKKFGM
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: KAD2_ASPCL
Sequence: MAPITDEAVNGLKDMIGKLEARVQELEGRLVGDLKPKSTAEQMRIILMGPPGAGKGTQAPRLKEKYCVCHLATGDMLRSQVAKKTELGKEAKKIMDQGGLVSDEIMVNMIKSELETNSECKNGFILDGFPRTVAQAERLDDMLEARKQKLQHAVELQIDDALLVARITGRLVHPASGRSYHKIFNPPKNEMLDDITGEPLIQRSDDNAETLKKRLSTYHAQTAPVVDYYKKTGIWRGIDASQEPGQVWKSLLGVFQK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: SAS2_BACCR
Sequence: MSRSTNKLAVPGAESALDQMKYEIAQEFGVQLGADATARANGSVGGEITKRLVSLAEQQLGGYQK
What is the function of this protein?
SASP are bound to spore DNA.  They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation.  They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light (By similarity).
What are the official names of this protein?
Small, acid-soluble spore protein 2, SASP.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.
Protein: HPT_PAPHA
Sequence: MSDLGAVVALLLWGQLFAVDSGNDVTDIADDGCPKPPMIANGYVEHLVRYQCKNYYRLRTEGDGVYTLNNEKQWTNKAVGDKLPECEAVCGKPKNPADAVQRILGGHLDAKGSFPWQAKMVSRHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLYPNYSQIDIGLIKLKQKVPVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFNFTDHLKYVMLPVADQYDCIKHYEGSTVPEKKTPKSPVGEQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEKDTWYAAGILSFDKSCGVAEYGVYVKATSIQDWVQKTIAEN
What is the function of this protein?
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine.  Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage.  Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response.  Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity).
What are the official names of this protein?
Haptoglobin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGH_HAHCH
Sequence: MKTLTLISLIMVTLLSGCSPISREQVRPGDPAFAPVPPQTLMQPAPVDGSIYSSAQNFSLFGDRTAHQVGDVLTVVLQESTQSSKSTGTSMKKDSENSFNEATILGTAISAHNLSLLTDQNFERDFSGEADADQSNSLSGSISVTISDVLPNGVLRIRGEKWLTLTEGDEYLRVSGLVRPQDIGVDNTILSSKIADARFAYSGAGAFGDVNRAGWLQRFFNSEWFPL
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: PETL_CHLSC
Sequence: MPTITSYFGFLLAASTITSALLIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SER_TABYA
Sequence: MLKYSALFLYLIYVGGSESAHSRIVGGVPVAEEKVPYVVSIRMKEIHVCGGSILSESIVLTAAHCFDKSKGYSNYAVFAGSNRLSGGLKVEIQNITIHPKYIGPSDWWKNDLAVVKLKKPLNFSKSVRTVKIFPSYVPENETVYAYGWGKTIVPFFTLPNVLQKLETKALNLTACQKSWKEHVVESQLCLWTGHGTGVGLCKADSGGPVVYKGKLVGVISWVQVHCNTKKPDVAVRLSPYFENGLRKR
What is the function of this protein?
Serine protease that inhibits blood coagulation in a dose-dependent manner.  May act by destroying coagulant factors to inhibit blood coagulation.
What are the official names of this protein?
Tabserin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NAGB_YERE8
Sequence: MRLIPLKNTTEVGKWAARYIVNRINAFKPTADRPFVLGLPTGGTPMEAYKHLVALYKAGEVSFKNVVTFNMDEYVGLPQEHPESYYTFMHSNFFDHVDIPAENINLLNGNAPDIDEECRRYEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLASRTRIKTLTEETREANSRFFGGDANLVPKYALTVGVGTLLDAEEVMILVTGRGKAQALQAAVEGSINHMWTISCLQLHAKAIMVCDEPSTMELKVKTVKYFSELEAENIKNL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: S22AI_MOUSE
Sequence: MAALPRQGIIILTYVLAALELTCLFMQFSILPYLSRTLGLDSVSFGYLQTTFGVLQLLGGPVFGRFADQCGARAALSLSFLAASALYLLLVASCSPALPGVFLLFASRIPSALMHTLPAAQMVITDLTAPTERPAALGRLGLCFGIGIIFGSLLGGTLNTAYGIQCPAILAFVVTLLGAVLSFTCVPATTKEASVQSAPQGGTKASVFDLKAITRLLLLPRVLPVFLVKVISGLPSGLFLVMFSIISMDFFQLEAAQAGYLMSFFGILQMMIQGLVIGRLSTHFPEEALLRSSVLVFAVVGLGMALMSSVLHFCFLMPGLVFSLCTLNVVTDSMLTKAVSASDTGTMLGLSASVQPLTRTLGPTLGGLLYRSYGVPIFGHVQLMVNLLVLLVLWKKPLSQKGEKAR
What is the function of this protein?
May act as a transporter of organic cations based on a proton efflux antiport mechanism.  May play a role in the transport of chloroquine and quinidine-related compounds in kidney (By similarity).
What are the official names of this protein?
Solute carrier family 22 member 18, Imprinted multi-membrane-spanning polyspecific transporter-related protein 1, Multi-membrane-spanning polyspecific transporter, Organic cation transporter-like protein 2, ORCTL-2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Localized at the apical membrane surface of renal proximal tubules.
Protein: RIFK_IGNH4
Sequence: MLAALYYVLKGDPYKALKEDLESLKKAKLLTEDLRITEKGMELIQQLISKPISLKGKVVSGDGEGRYYLSLEGYRRQVREKLGFDPFPGTLNVLLDPTSTEKKSTLMFKRPIILKGFTENGKRYGEVLAFPARVSGVEAALVIPLKTHHPPEIIELISPVELRKALKLKDGDEVEVLVY
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.