PharMolix/UniProtQA huggingface dataset:
Protein: PO121_MOUSE
Sequence: MSPAAAAADGGERRRPPLGGREGRSRARGYGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRALSSFVRDARRHPRPALTASPPPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALRQDPRERPGRRPPARSPPPASAVQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSPRNSRMVCSPVTVRIAPPDSKLFRSSMSEQILDTTLSSPSSNAPDPCAKETVLNALKEKKKRTVAEEDQLHLDGQENKRRRHDSGGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLASACTGGIPSSSRNAITSSYSSTRGISQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCQQSSSSPPLVTDKESPGEKVTDTTTGKQQSSWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERKASLQWFNKVLEDKPDDASASATDGPPSTSPPFTFTLPAVGPAASPASLPAPSSNPLLESLKKMQESPAPSSSEPAEAATVAAPSPPKTPSLLAPLVSPLAGPLASTSSDSKPAATFLGLASASSITPLTDSKSSGVSQAEQSVSTPASTASSPTPKPSMLFGMLSPPASSSSLATPAPACASPMFKPIFPATPKSESDSPLPSSSSAATTASSSTAPPTAASTTPTFKPIFDKMEPFTAMPLSTPFSLKQTTATATTTATSAPLFTGLGTATSTVASGTAASASKPVFGFGVTTAASTASSTMTSTSQSVLFGGAPPVTTSSSAPALASIFQFGKPLAPAASAAGTSFSQPLASSTQTAASNSGFSGFGSTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSSSAKPALPTYPGANSQPTFGATDGATKPALAPSFGSSFTFGNSVASAPSAAPAPATFGSAAQPAFGGLKAAASTFGAPASTQPAFGSTTSVFSFGSATTSGFGAAATAATTTQTTNSGSSSSLFGSSAPSPFTFGGSAAPAGSGGFGLSATPGTSSTSGTFSFGSGQSGTPGTTTSFGSLSQNTLGAPSQGSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGASSTPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK
What is the function of this protein?
Essential component of the nuclear pore complex (NPC).  The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane.  When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL) (By similarity).
What are the official names of this protein?
Nuclear envelope pore membrane protein POM 121, Nucleoporin Nup121, Pore membrane protein of 121 kDa.
What is the protein family that this protein belongs to?
Belongs to the POM121 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single- pass membrane protein. Note=Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase.
Protein: DPO1_KLULA
Sequence: MNYIINLKMDYKDKALNDLRNVYADFDSLPLDFRQILIKDRATLLQKEDVEKKILERQEDAKKYAEYLKQSEIPERISLPNIKRHKGVSISFEETSEDMVLEPRPFIFDGLNIRCFRRETIFSLKNKILNMVKESSSFKNVSRQSVSFMYFKIFNKGKVIASTKSVNIYEDKIDERLEDLCNNFDDVLKKIIDVTYGYESLFVSETYSYVIFYAKSIYFPQPRCVNNWGNNIPNILTFDSFKLFTANKNNVSCIKQCSRFLWQKDFNTLEEMIEYKNGNICIVTPQLHINDVRDIKSFNDIRLYSESPIKTFSVIDNTITYLFYFKEHLGVIFNITKSRHDRRVTKFSPLSKFSDVKNITVCFDIESYFDPEKESNQVNIPFICCASIIYNKVIGNIVDFEGRDCVAQMIEYVVDICGELNISSVELIAHNGGGYDFHYILSSMYNPAAIKNILIRNNSFISFNFAHDGVKFSVKDSYSFLLCSLANASKAFLNEETFKKTDFPHHDLKTADDLYKVYKEWSSVNTEINHVVEKEKLLITSEHIVNFTKNDKSKTLIEWSKDYCRNDVLVLSKVWLEFKNAVEDIFNCELVDQTMTLAGLSYKLFQANMPFDVELRHPNKEDYFNMREALIGGRCISVNGIYKDVLCLDVKSLYPASMAFYDQPYGSFKRVSSRPKDELGIYYVRVTPNRNNKSNFFPIRSHNKITYNNFEESTYIAWYTNVDIDIGLSEGHNIEYIPFDSYGNIGYSWSKKGKIFEKYIKDVLYKLKIKYEKQNNKVKRNVIKIIMNSLWGKFAQKWVNFEYFIKSEDDIDFESEEAYKIWDTDFMLIKKIKESTYSSKPIQNGVFTLSWARYHMKSIWDAGAKEGAECIYSDTDSIFVHKEHFKKNAKFMLNGLKVPIIGSEVGQLELECEFDKLLCAGKKQYMGFYTYFQDGKPCIKEKKRFKGIPSNYIIPELYAHLLSGADKEAKIQFLKFRREWGSVKGYIENKTVKAT
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: HOG1_HYPAT
Sequence: MAEFVRAQIFGTTFEITSRYSDLQPVGMGAFGLVCSARDQLTNQNVAVKKLMKPFSTPVLAKRTYRELKLFKHLRHENVISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQIMRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTAYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVINTIASENTLRFVKSLPKRERQPLRNKFKNADDSAIDLLERMLVFDPKKRITATEALAHDYLAPYHDPTDEPVAEEKFDWSFNDADLPVDTWKIMMYSEILDYHNVEGVPQMEDQQFPPQ
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase hog1, MAP kinase hog1, MAP kinase tmk3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRF_SYNJB
Sequence: MKGDRLIVALDTPSQEQALEWVDSLPQVLWWKVGLELFTAAGSSILQALKERGKRIFLDLKLHDIPHTVGRATEVAVGYGVDLLTVHAAGGSAMLRSAVAAAQGSSCRLLAVTLLTSISPPQVRQELGIEMDPADYVLHLARLAQAQGFTGLVCSPQEVSRLRQALGPEVLLVTPGIRLGQAKAGDGDEDQQRICTPDEALRAGADYLVVGRPITASPDPVAALRRFQALWDAAS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: NUP2_YEAST
Sequence: MAKRVADAQIQRETYDSNESDDDVTPSTKVASSAVMNRRKIAMPKRRMAFKPFGSAKSDETKQASSFSFLNRADGTGEAQVDNSPTTESNSRLKALNLQFKAKVDDLVLGKPLADLRPLFTRYELYIKNILEAPVKSIENPTQTKGNDAKPAKVEDVQKSSDSSSEDEVKVEGPKFTIDAKPPISDSVFSFGPKKENRKKDESDSENDIEIKGPEFKFSGTVSSDVFKLNPSTDKNEKKTETNAKPFSFSSATSTTEQTKSKNPLSLTEATKTNVDNNSKAEASFTFGTKHAADSQNNKPSFVFGQAAAKPSLEKSSFTFGSTTIEKKNDENSTSNSKPEKSSDSNDSNPSFSFSIPSKNTPDASKPSFSFGVPNSSKNETSKPVFSFGAATPSAKEASQEDDNNNVEKPSSKPAFNLISNAGTEKEKESKKDSKPAFSFGISNGSESKDSDKPSLPSAVDGENDKKEATKPAFSFGINTNTTKTADTKAPTFTFGSSALADNKEDVKKPFSFGTSQPNNTPSFSFGKTTANLPANSSTSPAPSIPSTGFKFSLPFEQKGSQTTTNDSKEESTTEATGNESQDATKVDATPEESKPINLQNGEEDEVALFSQKAKLMTFNAETKSYDSRGVGEMKLLKKKDDPSKVRLLCRSDGMGNVLLNATVVDSFKYEPLAPGNDNLIKAPTVAADGKLVTYIVKFKQKEEGRSFTKAIEDAKKEMK
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm).  As one of the FG repeat nucleoporins NUP2 is involved in interactions with and guidance of nuclear transport receptors such as SRP1-KAP95 (importin alpha and beta) through the NPC.  Like the closely related NUP1 it also plays an important role in disassembling and recycling SRP1-KAP95 to the cytoplasm after nuclear import.  Upon entry of the heterotrimeric SRP1-KAP95-cargo complex in the nucleus, NUP2 binds through its N-terminus to the SRP1 nuclear localization signal (NLS) binding site, thus accelerating the release of the NLS-cargo.  SRP1 in turn is released from NUP2 by binding of the GSP1-GTP associated export factor CSE1.  NUP2 may also have a chromatin boundary/insulator activity through indirect interaction with genomic DNA via CSE1 and blocking of heterochromatin spreading.
What are the official names of this protein?
Nucleoporin NUP2, Nuclear pore protein NUP2, p95.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.
Protein: PLY1_ARATH
Sequence: MAVLPTWLLAMMCLLFFVGAMENTTHDNISSLPRSDETEWNQHAVTNPDEVADEVLALTEMSVRNHTERRKLGYFTCGTGNPIDDCWRCDPNWHKNRKRLADCGIGFGRNAIGGRDGRFYVVTDPRDDNPVNPRPGTLRHAVIQDRPLWIVFKRDMVIQLKQELIVNSFKTIDGRGANVHIANGGCITIQFVTNVIVHGLHIHDCKPTGNAMVRSSETHFGWRTMADGDAISIFGSSHVWIDHNSLSHCADGLVDAVMGSTAITISNNHLTHHNEVMLLGHSDSYMRDKAMQVTIAYNHFGVGLIQRMPRCRHGYFHVVNNDYTHWEMYAIGGSANPTINSQGNRYAAPKNPFAKEVTKRVDTPASHWKGWNWRSEGDLLQNGAYFTSSGAAASGSYARASSLSAKSSSLVGHITSDAGALPCRRGRQCSS
What are the official names of this protein?
Probable pectate lyase 1, Pectate lyase A1.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
Protein: CYC_MACMU
Sequence: MGDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGITWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE
What is the function of this protein?
Plays a role in apoptosis.  Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol.  Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity).
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: MPTA_MYCTU
Sequence: MTTPSHAPAVDLATAKDAVVQHLSRLFEFTTGPQGGPARLGFAGAVLITAGGLGAGSVRQHDPLLESIHMSWLRFGHGLVLSSILLWTGVGVMLLAWLGLGRRVLAGEATEFTMRATTVIWLAPLLLSVPVFSRDTYSYLAQGALLRDGLDPYAVGPVGNPNALLDDVSPIWTITTAPYGPAFILVAKFVTVIVGNNVVAGTMLLRLCMLPGLALLVWATPRLASHLGTHGPTALWICVLNPLVLIHLMGGVHNEMLMVGLMTAGIALTVQGRNVAGIILITVAIAVKATAGIALPFLVWVWLRHLRERRGYRPVQAFLAAAAISLLIFVAVFAVLSAVAGVGLGWLTALAGSVKIINWLTVPTGAANVIHALGRGLFTVDFYTLLRITRLIGIVIIAVSLPLLWWRFRRDDRAALTGVAWSMLIVVLFVPAALPWYYSWPLAVAAPLAQARRAIAAIAGLSTWVMVIFKPDGSHGMYSWLHFWIATACALTAWYVLYRSPDRRGVQAATPVVNTP
What is the function of this protein?
Involved in the latter stages of the biosynthesis of the alpha-(1->6) mannan core of lipomannan (LM).  Catalyzes the addition of alpha-(1->6)-mannose residue.
What are the official names of this protein?
Alpha-(1->6)-mannopyranosyltransferase A, MptA, Polyprenyl-1-monophosphorylmannose dependent alpha-(1->6)-mannopyranosyltransferase, PPM-dependent alpha-(1->6)-mannopyranosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MptA/B family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PDXJ_SULNB
Sequence: MLLGVNIDHIAVLREARKVADPDPLDALGICKRARADQITIHLREDRRHMHDMDAKNIIELSALPVNLECATEPSMIDIACRLRPHRVTLVPEKREEVTTEGGLAVTGEQTRLQEAIKRLQEKEIEVSLFIDPASDAVKASSDLGVEWIEFHTGKYANIYAMLYSNLSKTHHSIPELKLPRSVLKKMLEEELESLSALSAEARVLGLKVAAGHGLNYHNVQAVAQIEEIEELNIGQSIIARSVYTGLEQAILDMKSLL
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_VIBVY
Sequence: MSDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTKKVIIGKDTRISGYMLESALEAGLAAAGLKATFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSSEGTKLPDDIELAIEAELDKEIECVESAELGKATRLNDAAGRYIEFCKSTFPSELSLAKLKIVVDCANGATYHIAPNVFTELGADVIAMGVTPNGTNINHEVGATDVRALQQRVVEEQADLGLAFDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEKLLEKGWKIGAENSGHVILLDKVTTGDAIVAALQVLASVVGSELSLNELSKGMTLYPQVLENVRFAGQGNPLEAEAVKKAVEEVEADLGSKGRVLLRKSGTEPLIRVMVEGEDGELVQNSALKIAQAVKDNC
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CCSA_GLOC7
Sequence: MNLVNLENILDNTSFLVLFLTMMIYWVGAAFPSVPYLQALGTAGVAIANLCIAALLGARWIEAGYFPISNLYESLFFLAWGVTAAHLIAQQMSRSHLVGVVTTPVAMGISAFAALTLPADMQTSAPLVPALKSNWLMMHVSVMMLSYATLMVGSALAIAFLFVTKGQNVELHGSSVGTGGYRTGVRLNKPQPVQETAIEGSGNVAVLNTTVVSDAPSLSLQRLSIADTLDNISYRIIGLGFPLLTIGIIAGAVWANEAWGSYWSWDPKETWALITWLVFAAYLHARITKGWQGRKPAILAASGFVVVWVCYLGVNLLGKGLHSYGWFF
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MVD1_SCHPO
Sequence: MDKKVYQCTVSAPVNIAVIKYWGKRDVALNLPTNSSISVTLSQDDLRTVTTASCSEKFENDTLWLNGNAEEIFANKRLRVCVEELRKARLDLEEENDDLDKIGALKLHVVSENNFPTAAGLASSAAGYAAFCEAIARLYDLPWTPTQLSRIARQGSGSACRSLFGGYVAWEMGELHSGADSVAVQVEPVENWPEIRVAVLVASAAKKGVSSTAGMQATVASSTLFQHRIQNIVPQRIQEMKTAIRERDFETFAKLTMTDSNQFHACCLDTFPPIFYLNDTSRAVIRVVENINATAGKTIAAYTFDAGPNAVIYFLEENSEIVLNTLYAVTKNAEGWSKQYGSSPVTVDSAAANIVSSGISRVILTRVGNGPRVLTIDESLIDASGNPKFIGSH
What is the function of this protein?
Diphosphomevalonate decarboxylase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (By similarity).  Mvd1 converts diphosphomevalonate into isopentenyl diphosphate (By similarity).  The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.  Activity by the mevalonate kinase erg12 first converts mevalonate into 5-phosphomevalonate.  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase erg8.  The diphosphomevalonate decarboxylase mvd1 then produces isopentenyl diphosphate.  The isopentenyl-diphosphate delta-isomerase idi1 then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).  Finally the farnesyl diphosphate synthase fps1 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (Probable).
What are the official names of this protein?
Diphosphomevalonate decarboxylase, Mevalonate pyrophosphate decarboxylase, Mevalonate-5-diphosphate decarboxylase, MDDase.
What is the protein family that this protein belongs to?
Belongs to the diphosphomevalonate decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GCM2_DROME
Sequence: MVVINGYSFKTQQLLTQQPDHSQLTQFVQPQSQSTHSVHPGPSPGQQQAGGSMTMPSSSTGKGKREWDINDAIVPHVPDQEFDEFNEWSDGHVRHIYSLHNEEAKKHISGWAMRNTNNHNVNILKKSCLGVLVCSQHCTLPNGSKINLRPAICDKARRKQEGKACPNKSCRGGRLEIKPCRGHCGYPVTHFWRHSGNAIFFQAKGVHDHLRPDPKNSSVSKRAFGRVPLAGKSANGSVAKKSVIAGLVKQAKQQHSLISKVLKRPAVSNPLAHTALDIYQYNACGKCAGYSHCTCSYLDDSTTARSHQLSQSSNYGTNSWPLSGSESSAPCETAANVFTVNHQHITYNYPIYHATPAAATAAPSKSPSLPYACSISELAAYQQSSSGNSFAMGVPVHGHTQCQAVAYDSSPQLATPEPEFINYSQIKHLGGGGGQEEISCKAEPGPTIKYNATVETQPYVEDNYDYYYSPKAEYEMQQHHHQQQQSHQQFGGNQTAGHHYYESSSGYNGVSYFDTGTTTAPGNTATGNGLEVGYGGYYDHYTSYEQQMAVAGGFATAGGSTAPTVAAPPGHPPPPPPPPTLTYHHHHHHHLHHPAAATGLAPSVTH
What is the function of this protein?
Transcription factor with a minor role promoting glial cell differentiation and a more significant role in hematocyte differentiation.  Gcm2, together with gcm, is required for the proliferation of plasmatocyte precursors, the expression of Croquemort protein, and the ability of plasmatocytes to convert into macrophages.
What are the official names of this protein?
Transcription factor glial cells missing 2, Protein glide-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CDAN1_HUMAN
Sequence: MAAVLESLLREEVSVAAVVRWIARSTQGSEDNAGEAAALSSLRALRKEFVPFLLNFLREQSSRVLPQGPPTPAKTPGASAALPGRPGGPPRGSRGARSQLFPPTEAQSTAAEAPLARRGGRRRGPGPARERGGRGLEEGVSGESLPGAGGRRLRGSGSPSRPSLTLSDPPNLSNLEEFPPVGSVPPGPTGTKPSRRINPTPVSEERSLSKPKTCFTSPPISCVPSSQPSALDTSPWGLGLPPGCRSLQEEREMLRKERSKQLQQSPTPTCPTPELGSPLPSRTGSLTDEPADPARVSSRQRLELVALVYSSCIAENLVPNLFLELFFVFQLLTARRMVTAKDSDPELSPAVLDSLESPLFQSIHDCVFFAVQVLECHFQVLSNLDKGTLKLLAENERLLCFSPALQGRLRAAYEGSVAKVSLVMPPSTQAVSFQPETDNRANFSSDRAFHTFKKQRDVFYEVLREWEDHHEEPGWDFEKGLGSRIRAMMGQLSAACSHSHFVRLFQKQLLQMCQSPGGAGGTVLGEAPDVLSMLGADKLGRLWRLQERLMAPQSSGGPCPPPTFPGCQGFFRDFILSASSFQFNQHLMDSLSLKIQELNGLALPQHEPNDEDGESDVDWQGERKQFAVVLLSLRLLAKFLGFVAFLPYRGPEPPPTGELQDSILALRSQVPPVLDVRTLLQRGLQARRAVLTVPWLVEFLSFADHVVPLLEYYRDIFTLLLRLHRSLVLSQESEGKMCFLNKLLLLAVLGWLFQIPTVPEDLFFLEEGPSYAFEVDTVAPEHGLDNAPVVDQQLLYTCCPYIGELRKLLASWVSGSSGRSGGFMRKITPTTTTSLGAQPSQTSQGLQAQLAQAFFHNQPPSLRRTVEFVAERIGSNCVKHIKATLVADLVRQAESLLQEQLVTQGEEGGDPAQLLEILCSQLCPHGAQALALGREFCQRKSPGAVRALLPEETPAAVLSSAENIAVGLATEKACAWLSANITALIRREVKAAVSRTLRAQGPEPAARGERRGCSRACEHHAPLPSHLISEIKDVLSLAVGPRDPDEGVSPEHLEQLLGQLGQTLRCRQFLCPPAEQHLAKCSVELASLLVADQIPILGPPAQYRLERGQARRLLHMLLSLWKEDFQGPVPLQLLLSPRNVGLLADTRPREWDLLLFLLRELVEKGLMGRMEIEACLGSLHQAQWPGDFAEELATLSNLFLAEPHLPEPQLRACELVQPNRGTVLAQS
What is the function of this protein?
May act as a negative regulator of ASF1 in chromatin assembly.
What are the official names of this protein?
Codanin-1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane; Multi-pass membrane protein. Note=Mainly detected as a cytoplasmic protein.
Protein: RL14_DEHMB
Sequence: MVQQYTRLNVADNTGAKKIMCINVLGGSHKIQAKVGDVIVAAVKKSSPDAQAKSGTVVKAVVVRITKPYARPDGSYIKFDDNAAVILNDKMEPKGTRIFGPVARELRDKKFTKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: REC16_SCHPO
Sequence: MDSDRCLTDEISLNTLSSTFASDNNLRRKENFLKSRYPSKFDLNVSMLTKSDDVGKTPFSIFDSPSNPGFSRSHQMCSDKNKSPFLFDKIRDEPVSVDPVKLIINNRNKRKINRQKSRLQGLYRSDANGLQPLNSENVKMKKSTALSLTSSPLNSWKTDFKTPPKANVVCISLVIEGDGCASLLYEDLNQISNSCPEVAPNRQNALFSDETLTTMFYSGVTEDEGSCNNLLQSSFGDDLDLGMQRSATWAPGYNYPSKFDSIPFASASPKIKAAFPFDPNVYALNTNDGPVTSTDNNCDQLNTRMQAWNNGFNYSNLNGDIQYPAVTPKFFQQEGRALNVSDCNFGNEEIAYGGIPMRVCHSDSTLCDARIAAKQALKGKRQYDTSTSKAELSTPPSKRRHIDDADLVFHSSPLLSRSRFICCYCTKPFLSISKLQEHESSCSHVERLFGFAPNRLYDDGDGFLGSSFCSDW
What is the function of this protein?
Transcriptional activator that controls the onset of premeiotic DNA synthesis by regulating res2 and some other factor(s) in a mei2 independent cascade.
What are the official names of this protein?
Transcriptional activator protein rec16, Zinc finger protein rep1.
What are the subcellular locations of this protein?
Nucleus.
Protein: AHLLB_AGRRK
Sequence: MGNKLFVLDLGEIRVDENFIIANSTFVTPQKPTVSSRLIDIPVSAYLIQCTNATILYDTGCHPECMGTNGRWPAQSQLNAPYIGASECNLPERLRQLDLSPDDISTVVLSHLHNDHAGCVEFFGKSRLIAHEDEFATAVRYFATGDHSSPYIVKDIEAWLATPRNWDLVGRDERERELAPGVNLLNFGTGHASGMLGLAVRLEKQPGFLLVSDACYTATNYGPPARRAGVLHDTIGYDRTVSHIRQYAESRSLTVLFGHDREQFASLIKSTDGFYE
What are the official names of this protein?
N-acyl homoserine lactonase AiiB, AHL-lactonase AiiB.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: PGDAE_HELPY
Sequence: MAKEILVAYGVDIDAVAGWLGSYGGEDSPDDISRGLFAGEVGIPRLLKLFKKYHLPATWFSPGHSIETFSEQMKMIVDAGHEVGAHGYSHENPIAMTAKQEEDVLLKSVELIKDLTGKAPTGYVAPWWEFSNITNELLLKHGFKYDHSLMHNDFTPYYVRVGDSWSKIDYSLEAKDWMKPLIRGVETDLVEIPANWYLDDLPPMMFIKKSPNSFGFVSPHDIGQMWIDQFDWVYREMDYAVFSMTIHPDVSARPQVLLMHEKIIEHINKHEGVRWVTFNEIADDFLKRNPRKK
What is the function of this protein?
Catalyzes the N-deacetylation of peptidoglycan (PG), an important mechanism that appears to confer lysozyme resistance and to mitigate host immune detection; this likely contributes to pathogen persistence in the host.  The exact nature of the residue in PG that is deacetylated has not been determined.  Is also able to catalyze the deacetylation of acetylated xylan, and, to a lesser extent, that of chitin and chitosan.  Therefore, this enzyme might play a role during infection, considering that xylan-containing carbohydrate structures are among those commonly consumed by humans.
What are the official names of this protein?
Peptidoglycan deacetylase, PG deacetylase, Acetylxylan esterase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
Protein: O1C5_CONCL
Sequence: MKVTCVLVVLLLLLPYGDLLGNSVCDFGSCVHNGCYCEEHRPCCTPGSCSSWWPRCPGSMMDP
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal12.5, O1_cal12c.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUDC_VIBCH
Sequence: MIRLQAIRRSRVEKSDGKNAYWCVVSGSDLWLVDGQIPYGSAEQWDLPQEKAILVDRYQNSPVYWLNAADIEQDRPLTSLRELLGVDEALFLAASKAVQYGHMSQTIRFCPQCGGRNYLNHQQLAMQCHDCRTLHYPRIFPCIIVAVRKQQQILLAQHPRHRNGMYTVIAGFVEVGETLEQCVAREVLEETGIVVTNIRYFGSQPWAFPSSMMMAFLADYDTGELKPDYSELSDANWFGIENLPPVAPRGTIARALIEQTLADIAQDQA
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: SLRA_BITRH
Sequence: MGRFIFLSSGWLVVFLSLSGTGADEGCLPGWSLYEGHCYKFFFIFKTWENAEKFCQEQSNGKNLASIEWLGKANFVAELVSQALTKTKYHVWIGLRREDEKQQCSSFWTDGSSVSYENVIRYTKCVGLNKNTGHRTWIALHCGDNYPFVCMSRLPH
What is the function of this protein?
Antagonist of the alpha-2 subunit of the integrin alpha-2/beta-1 (ITGA2/ITGB1) on human platelets and endothelial cells.  This protein inhibits collagen-stimulated activation of human platelets in a dose-dependent manner.  In addition, it antagonizes the binding of monoclonal antibodies against the alpha-2 subunit of integrin alpha-2/beta-1 to platelets and it coimmunoprecipitates with this integrin.
What are the official names of this protein?
Snaclec rhinocetin subunit alpha, C-type lectin like protein 1.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: PAND_FRATW
Sequence: MLISVLKSKISYATVTGKDLFYVGSITIDSEIMKQANIIENEKVQVVNLNNGERLETYVIKGEPNSKTIALNGPAARRCEIGDQLFIISYTQVDPTRENIKPKLVDLKTGD
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTC6_KOMPG
Sequence: MIIAFFLLIQCVYCVIWPPLSVDNEVALRSQRDVSYNVSVDQLVDVGVRLSTVIFERDTYTQPYLNRVDNLLNASVGNILIDAYWDEGGFNWQLCPAPFSANVTPIADGSTILQLEWDNKQYTCDRRLDLASIFTRIDEHIRASARSVSLNLITIYMSLHSIGTQNPTPVSQPGTLSRPLVRSIDQVQILTPASLRVAQLSNSTYQGLEFDPNGYPILGELLQSRGIRVIPIILENNMYEDTSYELERDSNLYFIQNSTIDVTQTNTADTKLTDLTTNITNWTIADSQALLSESFRLVMETEEDPFSLESYTNHISHGYSPFLNRKYNESEIRQFAVNRLWSWKNSYLPEVSVPLLGDQDDSNSANETLQCASFSNLSWIISSCDEPRQVACRNSSYWLQWTVTSTLSNYYGATEACPVGTFFDIPRTPLDSMTLQREIPLNSSVWIDLNTLDSGGCWISGGAEAECPYHRVTLVSLYVEILTPSSVVSIVLIAIVVLLHFVRIPIQKNRKYWRKLQDNIKDSDGIPS
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 6.
What is the protein family that this protein belongs to?
Belongs to the MTC6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.