PharMolix/UniProtQA huggingface dataset:
Protein: CAS2_DICTD
Sequence: MYVIMVYDVNQRRINKVLNTARKYLEWIQNSVLEGEITEAKFEMLKREIEIIINEEEDSVIFYIMRTTKYSERQILGIEKNKREQIL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: VATB_STRSV
Sequence: MSVIKEYRTVSEVVGPLMIVDQVAGVHFNELVEIQLHDGSKRQGQVLEVQEDKAMVQLFEGSSGINLEKAKVRFTGRPLELPVSEDMVGRIFNGMGKPIDGGPAILPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKELAAQIARQATVLNSDENFAVVFVAMGITFEEAEFFMNDLRETGAIDRSVLFINLANDPAIERIATPRIALTAAEYLAYEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYPGYLYTNLSTLYERAGRLVGKKGSVTQIPILSMPEDDITHPIPDLTGYITEGQIILSRELYNSGYRPPINVLPSLSRLKDKGSGEGKTRGDHAATMNQLFAAYAQGKQAKELAVVLGESALSETDKLYVRFTDRFEQEYINQGFQTNRTIEESLDLGWELLSILPRTELKRIKDDMIDQYLPQTKEEER
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: HSLV_PASMU
Sequence: MTTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELFERKLEMHQGHLLKSAVELAKDWRTDRALRKLEAMLIVADEKESLIITGIGDVVQPEADQILAIGSGGNFALSAARALVENTELSAREIVEKSLKIAGDICVYTNTHFTIEELPNS
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNC_PSEAB
Sequence: MTIKAILTDIEGTTSAVSFVFDVLFPYAARHLPDFVREHAGEPEVAAQLAAVRAESGEADADVERAIAILLQWIAEDRKATPLKALQGMVWAQGYRDGQLKGHVYPDAVQALREWKARGLDLYVYSSGSIQAQKLIFGCSEAGDLGPLFSGYFDTTSGPKRESASYARIAGAIGLPAAEILFLSDVVQELDAARDAGMRTLGLAREGGSLDGHPTVASFADIVVE
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: KMT_SULIR
Sequence: MSYVPHVPYVPTPEKVVRRMLEIAKVSQDDIVYDLGCGDGRIIITAAKDFNVKKAVGVEINDERIREALANIEKNGVTGRASIVKGNFFEVDISEATVVTMFLLTNVNEMLKPKLEKELKPGTRVVSHEFEIRGWNPKEVIKVEDGNMNHTVYLYVIGEHK
What is the function of this protein?
Catalyzes the methylation of lysine residues in target proteins, using S-adenosyl-L-methionine (SAM) as the methyl donor.  Exhibits broad substrate specificity, being able to methylate the crenarchaeal chromatin protein Cren7 primarily at 'Lys-11', 'Lys-16' and 'Lys-31', as well as a number of recombinant Sulfolobus proteins in vitro.  Methylates lysine residues in a rather sequence-independent manner.
What are the official names of this protein?
Protein-lysine N-methyltransferase, Archaeal protein lysine methyltransferase, aKMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily.
Protein: RIMM_XANOM
Sequence: MKQTERRILLGRVVGAFGVKGELKLESWTEPRSAIFRYQPWIVRAPSGQESVINGVRGRDQGKNLIAVFPGVADRDTVEAMHGTEIYVARSALPPPKPDEYYWVDLEELQVETVEGVKLGTVSHLFSTGSNDVVVVRGDRERMIPFVFPDFVKSVDFEANLIVVDWDPDF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1322_MYCTO
Sequence: MARRRKPLHRQRPEPPSWALRRVEAGPDGHEYEVRPVAAARAVKTYRCPGCDHEIRSGTAHVVVWPTDLPQAGVDDRRHWHTPCWANRATRGPTRKWT
What are the official names of this protein?
Uncharacterized protein MT1363.1.
Protein: TYRA_SHEON
Sequence: MNEKTTSELEHLRGLIDGVDQQLLHLLRKRLDLVAQVGTVKHAAGLPIYAPQREAAMLAKRREEAQTMGIAPQLIEDILRRLMRESYLNEKDVGFKQVKNDLGSVVIVGGKGQLGGLFQQMLRLSGYQVKVLDKDDWQQAECLFADAGLVLVTVPIAITCDIIREKLTQLPRDCILADLTSIKTEPMQAMLAAHKGPVVGFHPMFGPDVGSLAKQVVVVCHGREADKYQWLLEQIAIWGARIVEAEPECHDNAMQLVQAMRHFSTFVYGLNLCKEEADIETLLKFSSPIYRLELAMVGRLFAQSPELYADIIFAQQESQHAIGDYLDNYREALELLKRGDREEFINQFQMVAKWFGDFAPQFQRESRMMLQSVSDMKTN
What are the official names of this protein?
T-protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prephenate/arogenate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHO_MYCTO
Sequence: MTDTDLITAGESTDGKPSDAAATDPPDLNADEPAGSLATMVLPELRALANRAGVKGTSGMRKNELIAAIEEIRRQANGAPAVDRSAQEHDKGDRPPSSEAPATQGEQTPTEQIDSQSQQVRPERRSATREAGPSGSGERAGTAADDTDNRQGGQQDAKTEERGTDAGGDQGGDQQASGGQQARGDEDGEARQGRRGRRFRDRRRRGERSGDGAEAELREDDVVQPVAGILDVLDNYAFVRTSGYLPGPHDVYVSMNMVRKNGMRRGDAVTGAVRVPKEGEQPNQRQKFNPLVRLDSINGGSVEDAKKRPEFGKLTPLYPNQRLRLETSTERLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQDIANAITRNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLSPDEFAIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKTTPGSMDSD
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: CHLP_TOBAC
Sequence: MASIALKTFTGLRQSSPENNSITLSKSLPFTQTHRRLRINASKSSPRVNGRNLRVAVVGGGPAGGAAAETLAKGGIETFLIERKMDNCKPCGGAIPLCMVGEFDLPLDIIDRKVTKMKMISPSNVAVDIGQTLKPHEYIGMVRREVLDAYLRDRAAEAGASVLNGLFLKMDMPKAPNAPYVLHYTAYDSKTNGAGEKRTLEVDAVIGADGANSRVAKSINAGDYEYAIAFQERIKISDDKMKYYENLAEMYVGDDVSPDFYGWVFPKCDHVAVGTGTVTHKADIKKFQLATRLRADSKITGGKIIRVEAHPIPEHPRPRRLQDRVALVGDAAGYVTKCSGEGIYFAAKSGRMCAEAIVEGSEMGKRMVDESDLRKYLEKWDKTYWPTYKVLDILQKVFYRSNPAREAFVEMCADEYVQKMTFDSYLYKKVAPGNPIEDLKLAVNTIGSLVRANALRREMDKLSV
What is the function of this protein?
Catalyzes the reduction of geranylgeranyl diphosphate to phytyl diphosphate, providing phytol for both tocopherol and chlorophyll synthesis.
What are the official names of this protein?
Geranylgeranyl diphosphate reductase, chloroplastic, Geranylgeranyl reductase.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. ChlP subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PR20A_HUMAN
Sequence: MEEPRPSKRLRSMAPNQASGGPPPEPGCCVADPEGSVEADGPAQPAQPAKPIAYVKPFRRQPPARPESPPPAERGRRRGGSRRPGRGRGRRAGPRGDAGQRQGAEGLMAPDVHIQLDHHGEPGHQGEPEITETAAFSLSETGPPPGTVQEGPGPDVAQPELGFQEPPAAPGPQAVDWQPVLTLYPCIGFRALGDSAVLQVIQTPQGTYVQGVPVFLTDIAY
What are the official names of this protein?
Proline-rich protein 20A.
What is the protein family that this protein belongs to?
Belongs to the PRR20 family.
Protein: MSRB_BURM9
Sequence: MSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGIYHCVVCGTALFESGAKFHSGCGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPERK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: PURL_CAMHC
Sequence: MDQKTIKAHKISDSEYKKILEILGREPNLLELGIFSSMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDIGDGMAAVFKMESHNHPSYIEPFQGAATGVGGILRDIFTMGARVEVNMNSLRFGDVIGDSKVNRYQRYLVKGVVGGIAHYGNCMGIPTIGGETTFDSSFNGNILVNAFALGIVKSDEIFYGKAEGAGNPVIYVGSKTGRDGLGGAVMASDSFNEENKSLRPTVQVGDPFAEKLLMEACLELFKKGYIIGIQDMGAAGLTSSSFEMAGRSGSGMIMHLDKVPMRENEMTPYELMLSESQERMLICAKKGCEEKVKEIFAKWDLDAEVIGEVTNSGNMELFWYGKKVADVPIAPLSEAAPILDRPVKKPAYLDKIASGNLCGCGVSKISNKEAFDKIFAEPEILNKNFIYDQYDANIGTNTIKKPGFLGAAAIRVKENGVNLCMAMDCNSRMNYINPRIGAALAVAASGRKVAMSGAVPLAITDCLNYGNPQNEEVMWQFAQGCEGIKAACKALNTPVVSGNVSLYNETDGVSIQPTPAIVMVGTAKNALLPSHFTKNGVNVYLIGDTKGVFAGSLYMKVVENRITGTLPEIDFIKERALWDLVIEANKCEILEFANSVGVGGVAITLAKMACIEQIGGNFDMIVDDDRDIFDESFSRAIVGVKNETEFLKLAKKSGLKFTKLGASGGETFKINEISVKIKQLAEIYFNKFSQIIKGETF
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_SACEN
Sequence: MRTDAAGGTYLDPSAADVTALLERVHLVGIGGAGMSGIARILLARGRQVSGSDARDSRTVLALKAQGAHIALGHRAENIEQFDGDPTAVVVSTAIRRDNPELVAAQERGVPVLRRAEALAALMADHRVACVAGTHGKTSTTSMLTVALQHCRLDPSFAIGGDLNESGANAHHGDGGVFVAEADESDGSFLVFAPSVAVVTNVEPDHLDHHGTAEAYTEVFQRFVERIEPGGVLIACADDAGAALLADQAEAAGVRVRRYGHEVTADGDARMVGYRPEHGSGVVTVEVSGDRLDVQVAVPGEHMAANAVAALLAGLELGAPLEGLLEGLAAFGGVRRRFEFKGRADGVRVYDDYAHHPTEVDAQLRAARPVVGDGRLVVVFQPHLYSRTAAFSGEFATALGLADEVVVLDVYGAREDPQPGVTGELIAESVPLPAERVHYEASFTAAAPLVAGLVQPGDLVLTMGAGDVTMLGPEILAEVERESGATEEDA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_SHIDS
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PAND_ECO55
Sequence: MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_LATSS
Sequence: MPTISVNLTTQKYQIKIENGLATSIGREVQRVWSVRKIALVTDTIVGPLYQAQITEQLTQAGFQVTVLTIPAGESAKSLEQAMSLYEALLTANFNRSDGLIALGGGVVGDLTGFVASTYMRGLPFIQIPTSLLAQVDSSVGGKTAVDLPAGKNLVGTFYQPELVLIDPQMLETLPQRQLVTGYAEVVKIAALVGADFWNLVQQIESPTAILDKAPELIARSIAYKAQIVMADVQESGQRRLLNFGHTIGHAVESLADGELTHGEAVSIGLIAISRLFEQPTQIAAQLQTVLERVGLPVTHPLLQSPALFEKIAHDKKNQGALINIVYLKAIGQPTILQLPLTQFSAQLKMKQRSF
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_BURA4
Sequence: MNLIAKLEQEEIERALAGKTIPEFAPGDTVIVNVNVVEGNRKRVQAYEGVVIAIRNRGLNSNFIVRKISSGEGVERTFQTYSPLLASIVVKRRGDVRRAKLYYLRERSGKSARIKEKLVSKDRTAAASQE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL24_PRUAV
Sequence: MVLKTELCRFSGAKIYPGKGIRFIRSDSQVFLFANSKCKRYFHNRLKPSKLTWTAMYRKQHKKDIAQEAVKKRRRTTKKPYSRSIVGATLEVIQKRRTEKPEVRDAAREAALREIKERIKKTKDEKKAKKAEVTKSQKSQGKGSIAKGGAQPKGPKLGGWRWQALSHCSVAYLLGSRVIDRTCLFV
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: RS12_LEPBJ
Sequence: MPTISQLIRHGRQKQKKRTKSPALKSSPQRRGVCTRVMTFTPKKPNSALRKVARVRLTTGIEVTAYIPGEGHNLQEHNVVLIRGGRVKDLPGVRYHIIRGTLDTLGVDKRRNGRSKYGAKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PP2D1_MOUSE
Sequence: MNWELYSSPLRVFWRSKVWDEKTSTFTSDENLKIGKMVGKRRRPRPKRSIDLEDSTEQLISGDMVTFPCSVCYRELNKARNFLHKKHHNALSMLGFQWMGGRQPKPKLVSLHRECIISNLLRSSTYNEKVLHNVNYAFEFLWKKQVPSYFKLCDKVGETSTYSPNSNHLMIKGIAICSNNNSAWKAEPNCKFTVVNDFGDKANVCFFGLFDSHYGYAAADLASKEFQVLLLHQLSIQDPSYQMTAEQKQLINSFDTVFREEYRAREEAFSSTYKTFRTSRREYEDTHKAFAKAFWRMDRLLRLGRNETSRVRWSGCSALTCILEGGIKNPHANKDWEKTYQQGSTSLPFQKTPQIISGVLHLANAGNVQAVLCRNGKGFCLTKEHSTRNTKERRRVLYSEAVISSDDPYGLLDGHIKTTRGLGFHGNLRLKKSIIPAPQTISVPIDDLCQFLILATNGLWQVLDKKEVTALVITLFHAYKETHVPRPKSKPWPPIGLLSPPDSNIRVLFQYQPENEDIMSTADGTKGLSDSIYAEAYTHQGTFSPKVTPYDPCSTKENSSLPTIDSKQENEKELCIKNFYKGAAEYIGCELVSAAIEGGSRDSITVMVMFLNGSEYHRLT
What are the official names of this protein?
Protein phosphatase 2C-like domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: PI15A_DANRE
Sequence: MNENRLAIDILLLCISCGASALAGFSPTASSSLPATNLTDIGFAPPKYLTEAANIPKTRRKRYISQNDMLAILDYHNKVRGKVFPPASNMEYMVWDDTLAKTAEQWASTCIWEHGPRNLLRFLGQNLSVRTGRYRSILQLVKPWHDEVKDYSFPYPRDCNPRCPLKCYGPMCTHYTQMVWATSNKVGCAINTCHNMNVWGSVWKRATYLVCNYSPKGNWIGEAPYKVGVPCSMCPPSYGGSCSNNMCFPAVNSNYLHWFK
What is the function of this protein?
Serine protease inhibitor which displays weak inhibitory activity against trypsin (By similarity).  May play a role in facial patterning during embryonic development (By similarity).
What are the official names of this protein?
Peptidase inhibitor 15-A.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: CP20A_RAT
Sequence: MLDFAIFAVTFLLALVGAVLYLYPASRQASGIPGLTPTEEKDGNLPDIVNSGSLHEFLVNLHGRYGPVVSFWFGRRLVVSLGTADALKQHFNPNKTLDPFETMLKSLLGYRSGAGSGSEDHVRRRLYGDAVTAALQSNFPLLLKLSEELLDKWLSYPETQHIPLSQHMLGFALKFVTRMVLGDTFEGEQEVIRFQKIHGTVWSEIGKGFLDGSLDKNTTRKNQYQEALMQLEAILKKIIKERKGGDFSQHTFIDSLVQRNLNEQQILEDSVVFSLAGCIVTARLCTWAIHFLTTAEEVQKKLHKEVDHVLGKGPITSEKIEQLRYCQQVLCETVRTAKLTPVSAQLQDIEGKVGPFIIPKETLVLYALGVVLQDASTWPSPHKFDPDRFADEPVMKVFSSLGFSGTWECPELRFAYVVTTVLVSVLLKKLHLLAVDRQVFEMKYELVTSCREETWITVSERH
What are the official names of this protein?
Cytochrome P450 20A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VSPS2_TRIST
Sequence: MELIRVLANLLILQLSYAQKSSELVVGGDECNINEHRSLVAIFNSTGFFCSGTLINQEWVVTAAHCDSKNFKMKFGAHSKKLLNEDEQIRNPKEKFICPNKKNNDVLDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSVGSDCRIIGWGSITPIEVTYPDVPYCANINLLDDAECKPGYPELLPEYRTLCAGIVEGGKDTCGGDSGGPLICNGQFHGIVSYGGHPCGQSLKPGIYTKVFDYNDWMKSIIAGNTAATCPP
What is the function of this protein?
Snake venom serine protease that degrades preferentially beta-chain of fibrinogen (FGB).
What are the official names of this protein?
Beta-fibrinogenase stejnefibrase-2, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
Protein: TRUA_CUPPJ
Sequence: MNRIAIGLHYDGAAFSGWQSQPHRNTVQDYLEDSIERFAGVRLLTTVAGRTDAGVHALGQVIHLDTTLDRTTFSWVRGINAFLPPSIALQWARPVDESFHARFLAFERMYYYALYTGPHRVPLAHGRAGYLMLPPGQRLDVDAMQAASRCLLGEQDFSSFRAAECQAKSPVKTMYDVTLKADGNWVFLRFRASAFLHHMVRNLMGCLVAVGRGRYPPEWLAEVLAARDRKLAAPTFMPDGLYLADVKYPEAYKIPAADPSASLFHGVFRHDAA
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: YJJB_SHIDS
Sequence: MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVQALRWCALLGSIGHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSVDLSIPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRIA_MYCLE
Sequence: MLSVPHLDREFDYLVSAEQSDDAQPGVRVRVRFHGRLVDGFVLERRNDTEHFGKLGWLDRVVSAQPVLTAEVRRLVDAVVARYAGTRPDVLRLAVPTRHARVERETLAIPVSPLPLIPGPVDPSGWEVYGRGGQFLTALAESRAARAVWQALPGEQWADRFAEAAAQAIRAGRAALAIVPDQRDLDVLWRAVTTRVDERSVVALSAGLGQAVRYQRWLKVLRGSARLVIGTRSAVFAPVNDLGLVMVWSDADDMLAEPRAPYPHAREVAMLRAYQARCAALIGGYTRTAEAHALVRSGWAHDVVAARSVVRARAPRVVALDDSGYAEESDPAARTARLPSIALRAARSALAAGAPVLVQVPRRGYVPSLACGRCRTLARCRHCTGPLSLLDRATPGTVCCWCGRADLTLRCARCGSEVVRAVVVGARRTAEELGRAFAGMPVITSVGDTIVPEVGARPALVVATPGAEPRAPGGYGAALLLDTWALLGRQDLRAAEEALWRWMTAAALVRARGDGGVVMVVAEASIPTVQSLMRWDPASHAEAELAARTEVGLPPSVHIAAVDGTTGAVNELLQEARLPDEADLLGPVDLPQGVRRPAGTPLGAPISRLLVRVPREQGWQLAASLRRGIGVLSVRQTHQLVRVQIDPLHIG
What is the function of this protein?
Involved in the restart of stalled replication forks.  Recognizes and binds the arrested nascent DNA chain at stalled replication forks.  It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
What are the official names of this protein?
Probable primosomal protein N', ATP-dependent helicase PriA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PriA subfamily.
Protein: RECO_FLAPJ
Sequence: MQIKTKAIVISAIKYQEKSLIVKCFTLSDGLKSYFVRDAFSSKKSNQKIAYFQPLTILEIEAVHKNKGTLERFKEVKIATPFHSIHYDVIKSTIVIFISEILHHSIHEEEKNEAFFTFLETALHWLDNHDQIANFHLILLLETTKYLGFYPDISNTEHPFFEMTEGLFSPFHAISSLTEHETNLFKKLIDLKFDNSNTNTLHSTERQILLKILINYYSYHLDGFKKPKSLEVLKEVFS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: MTNN_ALISL
Sequence: MKIGIIGAMEQEVAILKEQINGLATTIKAGCTFHTGTLNGAEVVLLQSGIGKVAAAVGTTLLISDHNVDVVLNTGSAGGFDSSLNLGDVVISTEVRHHDADVTAFGYEMGQMAQQPAAFKADEKLMAVAEKALTQMEDKHAVRGLICTGDAFVCTPERQAFIRSHFPSVIAVEMEASAIAQTCHQFSVPFVVVRAISDVADKESPMSFEEFLPLAAESSSEMVMKMVTLLK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: CLCN4_RAT
Sequence: MDFLDEPFPDVGTYEDFHTIDWLREKSRDTDRHRKITSKSKESIWEFIKSLLDAWSGWVVMLLIGLLAGTLAGVIDLAVDWMTDLKEGVCLSAFWYSHEQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLVRVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVACCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTVFTRCNIAWCRRRKTTRLGKYPVLEVIVVTAITAIIAYPNPYTRQSTSELISELFNDCGALESSQLCDYINDPNMTRPVDDIPDRPAGVGVYTAMWQLALALIFKIVITIFTFGMKIPSGLFIPSMAVGAMAGRMVGIGVEQLAYHHHDWIIFRNWCRPGADCVTPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAVTSKWVADAFGKEGIYEAHIHLNGYPFLDVKDEFTHRTLATDVMRPRRGEPPLSVLTQDSMTVEDVETLIKETDYNGFPVVVSRDSERLIGFAQRRELILAIKNARQRQEGIVSNSIMYFTEEPPELPANSPHPLKLRRILNLSPFTVTDHTPMETVVDIFRKLGLRQCLVTRSGRLLGIITKKDVLRHMAQMANQDPESIIFN
What is the function of this protein?
Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons (By similarity).  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (By similarity).  The presence of conserved gating glutamate residues is typical for family members that function as antiporters (By similarity).
What are the official names of this protein?
H(+)/Cl(-) exchange transporter 4, Chloride channel protein 4, ClC-4, Chloride transporter ClC-4.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note=Localizes to late endosome membrane, lysosome membrane and recycling endosome membrane in the presence of CLCN3.