PharMolix/UniProtQA huggingface dataset:
Protein: OTSB_SALTY
Sequence: MAEPLTVSPELTANYAYFFDLDGTLAEIKPHPDQVVVPHKILQLLDRLAAHNAGALALISGRSMTELDALAKPFRFPLAGVHGAERRDINGKTHIVRLPEAVVREVEALLRSTLVALPGTELESKGMAFALHYRQAPEHEAALLALAQHVTQHWPQLALQPGKCVVEIKPKGTNKGEAIAAFMQEAPFAGRIPVFVGDDLTDEAGFGVVNHAGGISVKVGVGATQAAWRLESVPDVWRWLEQINYPQQEQQVMNNRRDGYESFSRSI
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
What are the official names of this protein?
Trehalose-phosphate phosphatase, TPP, Trehalose 6-phosphate phosphatase, Trehalose-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: MURC_RHOP5
Sequence: MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASESANVARLREKGIAISVGHKAENVAGADVVVVSTAIKRDNPELLAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGEFDPTVINGGIINAYGTNARLGAGEWMVVEADESDGTFLKLPADVAIVTNVDPEHLDHFKTFEAVQNAFRDFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGENPQADVRLLDLKPNGGASTFKVAFRDRKANTAHEIADLKLPMPGRHNALNATAAIAVAHELGLSDDTIRKALAGFGGVRRRFTKTGDWNGVSIIDDYGHHPVEIAAVLKAARESTKTKVIAVVQPHRFTRLQSLFEEFCTCFNDADAVIVAEVYPAGEAPIPGIDRDNFVLGLRAHGHREVIPLQESAALAGVVHSIAKPGDYVVLLGAGNITQWAYALPGELKALG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTGCB_BUCAP
Sequence: MFKNVFSSLQKVGKSLMLPVSVLPIAGILLGIGSAHFTLIPEIISQIMAQTGGSIFSNMPLIFAIGVALGFSNNDGVAALAAVVAYSILIQTLSAVELNILNTDANTIKNKNFSDIGILGGIIAGAISAYMFNKFYKIQLPEYLGFFAGKRFVPIISGLFAIFVGLILSLIWPSIGNKIQIFSEWAAYQNPIIAFSLYGLVERALVPFGLHHIWNVPFQMQIGEYKNSIGQIFHGDIARYMAGDTTAGNLSGGFIFKMYGLPGAALAIWHTAKKENRKKIGSIMISAALTAFLTGITEPIEFSFILVAPILYIIHAILAGLSFPLCIFLNMRAGTSFSHGFIDFIVLSGHSHKIFLFPIVGICYGLLYYSIFYFLITTFNLKTPGREENKNTVFFRNNIEIAPYIVEALGGKNNIKNLDACITRLRITVSEISKVNEENLKNLGAAGVVISGSGVQAVFGTRSENIKTAIDEYINNI
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of PtsG and Crr is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIICB component, EIICB-Glc, EII-Glc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSPB_ENDTX
Sequence: MEKLLNELSSENRPAYSVDSDVEIDAQIPENLKRSSGLGLPSITENDLSRHFTNLSRKNYALSTSFYPLGSCTMKYNPLINERVAKNEAFNFIHPYQPGKSMQGVLKIMYELEKDLCEISGMDCFSLQQAAGAHGEFTGLLIIAKYFKSIKQKRTKIIIPDTAHGTNPASAALAGFGTVSLKSESDGSILPEKLKKILTPEIAAVMLTVPNTLGAFEKNIPEISRIVHENGSLLYYDGANLNAVMGIVRPGDMGFDVMHINLHKTFSTPHGGGGPGSGPVGVKEFLEPFLPVPKIESRKSKFVLNYKKPKSIGKLKAFLGNFPVILKAYVYIKSLGAEGLKNVSEWAVLNANYMLARFKDKIDVPAGSRCMHEFVLSPKSLFKNNVKTLDVAKRLLDYGYYAPTIYFPLIVEEAVMLEPTETESKETMDAFIDTLIKIIYEEATQEPQKLKEAPFNTSVRRLNEVEAARNPVLKWKKA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: DRC6_MOUSE
Sequence: MASLRSATPRLRSYFRDKYIPQICEALLCGLLVTCPEDPLKYLEHMILAIIKRGLENLLWDTCIHPSLKSRVRRLSETYLDELFGLDDQLVTPELMIKACTFYTGHLVKTHFSGWKKVAIPRANQEEIMAEKMDKAIAHDNFRCQKYIFNRWFAYTVMSRERLITTLLRLRHLFYMQRQRIILAKWKERARHKSKTREDDLISKHELQLKKWKFKLGKPISLEGSLSDIAVENRRIAFDISVLPEQAILQIFLYLTFKDMMACSRVNRSWMAMIQRGSLWNSIDFSTVKNIADKCVVTTLQKWRLNVLRLNFRGCDFRTKTLKAVSHCKNLQELNVSDCQSFTDESMRHISEGCPGVLYLNLSNTTITNRTMRLLPRYFHNLQNLSLAYCRKFTDKGLQYLNLGNGCHKLIYLDLSGCTQVLVEKCPRISSVVLIGSPHISDSAFKALSSCDLKKIRFEGNKRISDACFKSIDRNYPGINHIYMVDCKGLTDSSLKSLSLLKQLTVLNLTNCIRIGDIGLKHFFDGPASIRLRELNLTNCSLLGDSSVIRLSERCPNLHYLNLRNCEHLTDLAIEYIASMLSLISVDLSGTLISNEGMTILSRHRKLREVSVSDCVNITDFGIRAYCKTSLLLEHLDVSYCSQLTDDIIKTIAIFCTRITSLNIAGCPKITDAGMEILSARCHYLHILDISGCIQLTDQIIQDLQIGCKQLRILKMQFCKSISPAAAQKMSSVVQHQEYNSDNPPHWFGYDSEGNPLDKIHSRVQLRTYSKLIVKEPFSIDEEDPDSKHQ
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.  Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
Dynein regulatory complex subunit 6, F-box and leucine-rich repeat protein 13, F-box/LRR-repeat protein 13.
What is the protein family that this protein belongs to?
Belongs to the DRC6 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: RPOA_HALH5
Sequence: MIEIEKPVIETIEISEDAKYGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVTSVQIDGVLHEFSTIEGVVEDVTTIVLNLKQLALKIYSDEDKTLEIDTQGEGVVTAGDLTHDSDVDVLNPDLHIATLTTGAHLRMRITAKRGRGYVPAEGNKSDELAIGVIPIDSIYTPVSRVNYQVENTRVGQVTNYDKLTLDVWTDGSIRPEEAVSLGAKILTEHLNIFVGLTDQAQNAEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELTQKTEEDMMKVRNLGRKSLEEVQEKLGELGLGLRKEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: C_MEASA
Sequence: MSKTDWNASGLSRPSPSAHWPSRKLWQHGQKYQTTQDRSEPPAGKRRQAVRVSANHASQQLDQLKAVHLASAVRDLERAMTTLKLWESPQEISRHQALGYSVIMFMITAVKRLRESKMLTLSWFNQALMVIAPYQEETMNLKTAMWILANLIPRDMLSLTGDLLPSLWGSGLLMLKLQKEGRSTSS
What are the official names of this protein?
Protein C.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus protein C family.
Protein: PTH_PYRAB
Sequence: MFKFKQVIVVRKDLKLSKGKLAVQVAHGAVTAAFKAYKEKREWFEKWFHEGQKKVVVKVESLDELFKLKAEAEKLNLPTALIQDAGLTEIPPGTITVLAIGPGPSEIIDKVTGHLKLL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS4_MESCR
Sequence: MASSLMSNAATTMAAATTTAQANMVAPFNGLKSISAFPVTRKNNDITSVASNGGRVQCMQVWPPLGMKKFETLSYLPPLSEESLLKEVQYLLNNGWVPCLEFEPTHGFVYREHGNTPGYYDGRYWTMWKLPMFGCTDPSQVVAELEEAKKAYPEAFIRIIGFDNVRQVQCVSFIAYKPASYGA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 4, RuBisCO small subunit 4.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MSHR_ALOPA
Sequence: MPMQGAQRRLLGSLNSTPTATPNLGLAANHTGAPCLEVSIPDGLFLSLGLVSLVENVLVVAAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLETAVILLLEAGALATRASVVQQLQNTIDVLTCSSMLCSLCFLGAIAVDRYVSIFYALRYHSIVTLPRARRAIAAIWVASVLSSTLFIAYCDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGITRLHKRQLPAHQGFGLRGAATLTILLGIFFLCWGPFFLHLMLVVLCPQHLTCSCIFKNFKVFLTLIICNTIIDPLIYAFRSQELCRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLR66_PLAVT
Sequence: MHLRLLMSTVITATLIVSNNALTSPSDKTKTRALRGASTVGIAADNLLAAHFSPTLKHKESRGDYNNIQTERHRKRRLYDAPHHPEFYDIAVHQVPSDKSYGGGPAIAIFAGVAATFILIDYLIRHFTEN
What is the function of this protein?
Effector that acts as a broad suppressor of cell death to interrupt plant immunity.  Inhibits cell death induced by cell death-inducing proteins, including the PAMP elicitor INF1 from P. infestans.
What are the official names of this protein?
Secreted RxLR effector protein 66.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus. Membrane; Single-pass membrane protein.
Protein: GPMA_RHIWR
Sequence: MPTLVLIRHGQSAWNLENRFTGWWDVNLTDQGIAEAKAAGELMAAKGLDFDQCYTSFQTRAIKTLNIALEAMGRLWLPVEKDWRLNERHYGGLTGLNKAETAARHGDAQVKVWRRSFDIPPPVLEPGGEFDLSKDRRYAGIAIPSTESLKDTIARVLPYWEERIAPDLKAGKRVVISAHGNSLRALVKHLSHIPDDEITELEIPTGQPIVYELADDLTARDRYYLSER
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: M2_I77AF
Sequence: MSLLTEVETPIRNEWECRCSDSSDPLVIAASIIGILHLILWILDRLLFKFIYRRFKYGLKRGPSMEGVPESMREEYRQEQQSAVDVDDSHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: LRC51_HUMAN
Sequence: MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRTTAEVWKRMNIKPKKAWTKQNTL
What are the official names of this protein?
Leucine-rich repeat-containing protein 51, Protein LRTOMT1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOME3_RAT
Sequence: MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFGSEQQLTQFAEKFQEVKEAARLAREKSQDGGELTSTALAMASHQVPPSPLVSTNGPEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNQRLAGALREANAAATQWRQQLEVQRAEAEHLRQRVAELEAQVAAEPVRAGEKEATSQSVEQLEARVQTKDQEIQTLKNQSTGPREAPDTAEREETQQQVQDLETRNAELEQQLRAMESNLEEARAERERARAEVGRAAQLLDVRLFELSELREGLARLAEAAP
What is the function of this protein?
Postsynaptic density scaffolding protein.  Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3.  By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release (By similarity).  Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway.  Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (By similarity).
What are the official names of this protein?
Homer protein homolog 3, Homer-3, VASP/Ena-related gene up-regulated during seizure and LTP 3, Vesl-3.
What is the protein family that this protein belongs to?
Belongs to the Homer family.
What are the subcellular locations of this protein?
Cytoplasm. Postsynaptic density. Synapse. Note=Postsynaptic density of neuronal cells.
Protein: PTH_FRATN
Sequence: MPKIKMIVGLGNIGKEYQDTRHNVGEWFIAKIAQDNNQSFSSNPKLNCNLAKVSIDYNNVVLVFPTTYMNNSGLAVSKVANFYKIAPAEILVVHDELDIDSGEIRLKKGGGHGGHNGLRSINQHLGTNDYLRLRIGIGHPGHKSKVANYVLSNPSIAQKKDIDSAIDNGICFLDDIINYKLEPVMQKLHTK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_CMVFN
Sequence: MDKSESTSAGRNRRRRPRRGSRSAPSSADANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCRPGYTFTSITLKPPKIDRGSYYGKRLLLPDSVTEYDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVAAISAMFADGASPVLVYQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDALETDELVLHVDIEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RUVA_DESVH
Sequence: MIAYVEGRLAEVAGNACVVVTDGGVGYEVFVPGHTLARLPDKGGRVSFFISTEVREDALELYGFATWDERQTFIVLTSISKVGAKTGLAILSQFRPDDLRRLVVEDDVLALTRVSGIGKKTAQHIFLELKYKLKVEDLPAAAPLVTGGAPGGVFRDALAGLANLGYGEEEASHVLKDVLHGEPDLDVGGALRAALRALARGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL4_BRUAB
Sequence: MDLTITTLEGKDAGKVKLNEEIFGLDPRDDILQRVVRWQLARRQQGSHKAQGRGDVSRTGSKMYKQKGTGRARHHSARAPQFRGGGQAHGPVVRNHDHDLPKKVRALGLRHALSAKAKASDLIIIDDLASADAKTKQLVSQFAKLGLENALLIGGAEIDANFQRAASNIPNIDVLPVQGINVYDILRRGKLVLSKAAVEALEERFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: BZR3_ORYSJ
Sequence: MTNGAGGGGGGGGLGGTRVPTWRERENNRRRERRRRAIAAKIYAGLRAYGNYNLPKHCDNNEVLKALCNEAGWTVEPDGTTYRKGCKPPQAERPDPIGRSASPSPCSSYQPSPRASYNPSPASSSFPSSGSSSHITIGGNSLIGGVEGSSLIPWLKTLPLSSSYASSSKFPQLHHLYFNGGSISAPVTPPSSSPTRTPRLRTDWENASVQPPWASANYTSLPNSTPPSPGHKIAPDPAWLSGFQISSAGPSSPTYNLVSPNPFGIFKEAIASTSRVCTPGQSGTCSPVMGGMPAHHDVQMVDGAPDDFAFGSSSNGNNESPGLVKAWEGERIHEECASDELELTLGSSKTRADPS
What is the function of this protein?
May function in brassinosteroid signaling.
What are the official names of this protein?
Protein BZR1 homolog 3, OsBZR3, Protein BRASSINAZOLE-RESISTANT 1 homolog 3.
What is the protein family that this protein belongs to?
Belongs to the BZR/LAT61 family.
Protein: SYE_METS3
Sequence: MNDLEEIVYKHALLNAAKHKGSANPGAVIGSIMSQEPDLRSRAKEIGPIAGKIVAQVNKLSEDEQSAQMAKYHVEVKENKQKKEEGLQELPGSHDNVVMRFAPNPSGPLHIGHARAAVPNAEYVKRYGGKLILRIEDTDPKRVFEPAYDLIPQDLEWLGIKADEVYYQSDRFEIYYDYARQLIEKGAAYMCTCDGATFKELKDNCKPCPCRDNSVEKNLELWDKFDQMHAGEAVLRVKTDINHKNPAIRDWVAMRIVEETHPRLGNKYRVYPMMNFSVAVDDHLMGMSHVLRGKDHLANSEKQKYLYDHMGWDVPEFIHYGRLKMEDIALSTSKALEGISSGKYSGWDDPRLGTLKAIARRGIQPQTIYNLITEIGVKMSDSAISWKKIYGLNRNFLEPIANRYFFVENPVEITVDGYEDGAVDIERPLHADHEDRGNRILPFAGKAYLASEDVKDGISRLMDAVNVDIDGDKITYNSTSFEQARDLKAKIIQWVPVEDNVNVSIVMDDASTKTGLGEGALKDLKVGDVVQFERVGFARLDEIKDNELVFYYAHK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_DECAR
Sequence: MSLTLEQVKRIAHLARIEISDDEALTTQGHLNGIFQLIEQMQAVDTTGIEPMAHAQDVSQRLREDAVSEGDRRAAYQAVAPEIEAGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: UBP16_HUMAN
Sequence: MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSEYEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL
What is the function of this protein?
Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator.  Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis.  In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes.  Regulates Hox gene expression via histone H2A deubiquitination.  Prefers nucleosomal substrates.  Does not deubiquitinate histone H2B.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 16, Deubiquitinating enzyme 16, Ubiquitin thioesterase 16, Ubiquitin-processing protease UBP-M, Ubiquitin-specific-processing protease 16.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP16 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURD_BLOFL
Sequence: MIRKYQKSNVVIIGFGKTGLSCLNFFLIRGVIPKIIDTRQYPSEMKNLPSFVEYCFGRLNDFWILNANLIVVSPGVRLDHPIIIEAMKLGIEVVGDIELFVREISAPIIAITGSNGKSTVTQLVSKMAKQAGWSVGVAGNIGVPVLSLLKKQYELYVLEISSFQLDVTYSLRATAATILNISVDHMDRYPKGLEEYICSKKRIYHNSYFCVVNDSDPLTKPLLNDGIYHVSFSMNSKSADYRLEYYKGNNWIVANGEYVLSCAELKINNCMNYMNMLSALALSDIVKIPRIVSLQVLRFFSGLSHRFQLVYKNRNVCWINDSKATNVGATKEAINNTIITLRDGNLHLLLGGDGKLANFFELSCLIKHYAIHLYCFGKDGVCLTQSGFNDVFLSNNIIDAMYIISRRVQRKDIVLLSPACASLDQFSSFRARGNLFTYLAQRLG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS8_PSEAD
Sequence: MSRFTSATHGLNLSIKMPISVSQVPSIRSNTSKYELQKLRSTGRSVLQTRRQLAIINMTKRSEADDNDGVERRKGVFHPNLWDDGFIQSLSTVYHEQASYRERAERLIGEVKAVFDSISMGDGDQFISPSAYDTAWVARVPAIDGSSRPQFPQAIDWILLNQQQDGSWGSQSHLSLTHRLTDTLACVIALASWKIESVQIDEGLDFITRGVEKLQSESVPAEFEIIFAELLNQAKSLQLSLPYEHSCLQSLWRKQEPILANGLMDSVAKRSLSSLEEMQDHRMNTDSDGTMHVESFLSSPAVAARVLMRTGNPICLAYLNNVLNKFGDYVPGMYPVDLFQRLWMVDNVERLGIDRHFKKEIQVTLDYVYSYWNGKGIGCGRDSLSPDLNSTSLGFRTLRLHGYNVSADVLEHFKDRDGKFVCSSNPTVGEIRSVLNLYRASLLAFPGEKVMEEAETFARRYLEEIVQKIPPSKFSREIEYVLEFGWQSTVPRWEARSYIDFHGLDTYSPWTIYEMASEKFLELAKLEFNIFNSLQHTELQYLSRWWNDSGMSQMRFTRHRNVEYYTMASCIAMEPSQSAFRIGFTKLCGIATCIDDIYDTYGTIDELKLFREAVKRWDPSAIESLPEYMKSVYMVLYELVNEMAQDTERTQGRDTLDYARNAWEAIIDAHLVEAEWIASGHIPTFEEYLENSKVTSGLHIAILPILTLDVPLPDQLPLQEIDTLSRFHHLASTIGRLSGDMNAYKIDLAHGEESSCISCYMKDNPGTTEGDAHNYANVTISYLMKELNLELMGQHNRVSFLRTSKKPAFDIYRASNYMYKYRDGYTIADKETKNLVMRTLVQAVSL
What is the function of this protein?
Converts geranylgeranyl diphosphate to an new 5,7-fused bicyclic diterpene, named pseudolaratriene (PubMed:28096378).  Catalyzes the first committed step in pseudolaric acid B (PAB) biosynthesis (PubMed:28096378).  PAB exhibits antiproliferative activity by inhibiting microtubule polymerization, and has demonstrated antitumor properties against several cancer types (Probable).
What are the official names of this protein?
Pseudolaratriene synthase, chloroplastic, Terpene synthase 8, PxaTPS8.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NADD_BACCN
Sequence: MKKIGIIGGTFDPPHYGHLLIANEVYHTLELDEVWFLPNQIPPHKRNRNVTSAEDRRKMLELAIEKEGYFSLCLEELEREGPSYTYDTMLQLTKKHPDTTFYFIIGGDMVEYLPKWYNIEKLLELVTFVGVARPGYTLQTPYKILTIEIPEFAVSSSLLRERYKNKKTCKYLLPEQVQSYIERNGLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.