PharMolix/UniProtQA huggingface dataset:
Protein: GAG_FRSF5
Sequence: MGQTVTTPLSLTLEHWEDVQRTASNQSVDVKKRRWVTFCSAEWPTFGVGWPQDGTFNLDIILQVKSKVFSPGPHGHPDQVPYIVTWEAIAYEPPPWVKPFVSPKLSPSPTAPILPSGPSTQPPPRSALYPALTPSIKPGPSPIMADLSLTFSQKTLRRTEDRDRPPLTEMATEKRPPPLLRFLPPLP
What is the function of this protein?
Matrix protein p15 targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus.  Also mediates nuclear localization of the preintegration complex (By similarity).
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion.
Protein: Y3035_BRUO2
Sequence: MDNKVETGNIDVRLLELLVCPLTKGPLEYDAERSELVSRKARLAYPVRGGIPIMLPSEARSLTE
What are the official names of this protein?
UPF0434 protein BOV_A0835.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PB2_I70A0
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPMTSTVHYPKVYKTYFDKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAIIRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMIGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDEGTSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: SUCC_LEGPL
Sequence: MNLHEYQAKQLFASYGLPVPRGEVAYNVEDALLVASQLSTSRWVVKAQVHAGGRGKAGGVKLVSSKDELAAVAKSMLGTRLVTYQTDARGQPVNAILVEETCEIDKELYLGAVVDRSTRRVVIMASTEGGVEIEKVAHETPEKIFKVVVDPLVGVMPFQCRETAFKLGLKDDQIKQFTHLMMGLGKMFVDCDLSLLEINPLVITKSGQLICLDGKINIDGNALFRQPKLKNMRDVSQEDDRENRASDWELNYIPLDGTIGCMVNGAGLAMATMDVIKLHGGEPANFLDVGGGATKERVSEALKIIVSDEKVKGILVNIFGGIVRCDLIADGILAAVKEVDVKIPVVVRLEGNNAQLGAEILNKSNLNVIAATSLTDAAKKIVAAVSE
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: YCHJ_SHIB3
Sequence: MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQDADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTEGGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ
What are the official names of this protein?
UPF0225 protein YchJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: RL5_RHOP2
Sequence: MAETAYVPRLRAEYDNSIRTQLTEKFGYGNVMQVPRLDKVVLNMGVGEAVNDRKKAEQAAADMALIAGQKAVVTYSRVAISTFKLRENQPIGCKVTLRKAKMYEFIDRLITVALPRVRDFRGLNPKSFDGRGNYSLGIKEHIIFPEIDFDKTGESWGMDITVCTTAGTDDEARALLTAFNFPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RS7_BORDL
Sequence: MSRKSKKIKKKVFKDSKYDSQVIAKFVNRMMYDGKKFISESIVYNSIDMLAEKLEEVDKVAAFNKALDNVKPLVEVRSRRVGGATYQVPVEVREERREALAMKWIISAARKASGKSMQEKLANELVNSYNSTGAAFKKREDTHRMAEANRAFTHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MURI_PSESM
Sequence: MPDIPVSQPVNPGCDAPVGVFDSGVGGLSVLNEIRQTLPNESLLYLADCGHIPYGEKTPEFIIERCLIIADFFHGQGAKALVVACNTATAAGVAHIRQRYPDWPIVGMEPAVKPAAEATRSGVVGVLATTGTLQSARFAALLDRFASDVSVVTQPCPGLVELIETGDLVSPQIRQLLQRYVEPLLAARCDTIILGCTHYPFLKPLLREMLPASVTLIDTGAAVARQLQRLLSRSGLLASGPARDTLYWSSDIPDNFGKILPFLSQMSGNVRSFRL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: MTGA_RHOPT
Sequence: MSDPVASAPRTKRVVRIVILVALALLALPYLLTILYGGGQPVSTLMLWRWATGAPVSRTWIDIENISPALPRSVVAAEDAKFCSHHGIDWDSVRDVIDDMQDGEASRGGSTITQQVAKNLFLWPGRSMIRKALEAPLALWIDFVLPKQRILEIYLNIAEWGPDGQFGAMAGADYAFGRSAAQLSAKEAATLAAILPNPRVRSAKAPGPGVRRLAATYVARARAAELRQCWRENRES
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PCKA_CERS5
Sequence: MNFGRVNPAQTLDAQGITGLGEVHYNLIEPALVEAAVKRGEGRLGRGGAFLCSTGAFTGRSPKDKFVVRTPSVEDTIWWENNAPMDPEAFDRLHADMLEHMKGRTYFVQDLFAGADPELRLDVRMVTELAWHGLFIRHMLRRPERTELDSFVPEWTVINCPSFKADPARHGCRTDTVITLNFDKKLILIANTEYAGENKKSVFTLLNYILPGKGVMAMHCSANHAIGNTDDAAVFFGLSGTGKTTLSADPSRTLIGDDEHGWSDKGTFNFEGGCYAKTINLSPEAEPEIYATTSKFATVVENMVYNEETLELDFDDDSLTANTRCAYPLEYISNASATGMGGHPKNVIMLTCDAFGVLPPIARLTPAQAMYHFLSGFTSKVAGTERGVTEPQPTFSTCFGAPFMPRRPEVYGKLLQEKITSLGATCWLVNTGWTGGAYGTGKRMPIKATRALLTAALDGSLANVTFRKDPNFGFEVPTELHGVDSSLLDPRSTWADPAAYDAQAKKLVEMFANNFAQYVPYIDADVKAAAIG
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2M_DROMA
Sequence: STVLLFSSILLMLKNNLNNEINESFTSMIIMSALLLKSGAAPFHFWFPNMMEGLTWMNALVLMTWQKIAPLMLISYLNIKYLLLISVILSVIIGAIGGLNQTSLRKLMAFSSINHLGWMLSSLMISESIWLIYFFFYSFLSFVLTFMFNIFKLFHLNQLFSWFVNSKILKFTLFMNFLSLGGLPPFLGFLPKWLVIQQLTLCNQYFLLLLMMMSTLITLFFYLRICYSAFMMNYFENNWIMKMNMISSNTNMYLIMTFFSIFGLFMISLFYFMF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UPPP_RHIME
Sequence: MADQSIISALVLGLIEGLTEFIPVSSTAHVLLAGHFLGFKSPGNTFAVLIQLGAILAILLVYFQKLLAIALALPTSVKARRFVFSVLLAFLPAALIGAAAHGFIKSVLFETPMLICVVLIVGGIILYAIDRLPLTPRYTDVFDYPPSLALKIGLFQCLAMIPGTSRSGATIAGALLMGTDKRSAAEFSFFLAMPTMVGAFALDLYKNRDALSFDDVGLIAAGFIAAFIAGIFVVRSLLDFVSHRGFTPFAIWRILVGTAGLVGLWLLG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDTB_ECO27
Sequence: MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYQALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFERIIAAYGQGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRP18_BOVIN
Sequence: MDVLKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKDEDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNELVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLMTICQKHFPTDPSKCVEYNAL
What is the function of this protein?
Participates in the second step of pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor 18, PRP18 homolog.
What is the protein family that this protein belongs to?
Belongs to the PRP18 family.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.
Protein: PUR5_STRMK
Sequence: MTNTPSSAPSPLTYRDAGVDIDAGNALVERIKPLVKRSFRPEVMGGLGGFGALFDLSNKYREPVLVSGTDGVGTKLKLAHQLNRHDTIGIDLVAMCVNDVLVQGAEPLFFLDYFATGKLDIDTAAAVVGGIANGCTEAGCALIGGETAEMPDMYAPGEYDLAGFTVAAVEKSELKDGASVAAGDVLIGIASSGPHSNGYSLVRRIYDRAGRPADLELEGGVKLVDALMAPTRLYVKPILSLLKSHGEAIHGMAHITGGGLTENIIRVVPDGLGLDIQASSWTLPPVFQWLQKEGAVADSEMWRTFNCGIGFVLIVAADQVAAVSDAVKAQGLEHWTIGQVVTAEGAERVHIG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MREC_CAUVN
Sequence: MRFREGPLGDLKVPLTWTAAVALIVAAVIGVAFLLADRRETLQEQAYGVTRQTVDTVARPVSGAIAAPGRWTGLGLDYVRSYFFTAHENRRLKAELAEMRQWRDRALALQDQNDRFKSLLGLRTDPPIPMAAARVVSDSRGPFANTRLADAGSERGIVVGNPVLNERGLVGRVVGVSRGVSRVLLLTDIASRTPVMIDRTNARAILTGDGGPNPKLDYLRGVDPIQQGDRVVTSGDGGVVPRGLPVGAAVKGLDGRWRVVLFADQASIDYVRILLFKDFAQLADEKQLQARSLPPVTTEDPQTSILSNPVSRPVAPTPSPATATPSAAPAARPATTATPPQTGAPR
What is the function of this protein?
Involved in formation and maintenance of cell shape.  Required for the spatial organization of components of the peptidoglycan-synthesizing holoenzyme in the periplasm and peptidoglycan synthetic activity.
What are the official names of this protein?
Cell shape-determining protein MreC, Cell shape protein MreC, Rod shape-determining protein MreC.
What is the protein family that this protein belongs to?
Belongs to the MreC family.
What are the subcellular locations of this protein?
Periplasm. Note=Localizes in helical or banded patterns along the cell length. This localization requires a normal cell shape, but is not disrupted in the absence of intracellular filaments formed by MreB.
Protein: MABA_MYCTO
Sequence: MTATATEGAKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTRALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH
What is the function of this protein?
Part of the mycobacterial fatty acid elongation system FAS-II, which is involved in mycolic acid biosynthesis.  Catalyzes the NADPH-dependent reduction of beta-ketoacyl derivatives, the second step of the FAS-II elongation cycle.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase MabA, 3-ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase, Beta-ketoacyl-acyl carrier protein reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: HDM_DROME
Sequence: MARRIKFQRLAEMRPTMTRFSTVALIVSKSSPNIFYDKMSGTERGVLSLTIRDSPNHLTNCKCWGQRDCVDEYAAMLQIGHVVDIVGAKVMSIPFAAPGEQRYQPQATVSCALVVNEGSGYVVRHDNDDFGQITILQQLLHQPIRPLGAVLKLADVRSGLGFPDKIITTNVNLLVVVAAVRPVRQIKRKLQGPLSEVQELLQCLEVIVIDASYPEGMLLSVWQPDWIQRAQQWQPRRTVLHLIDVRVSYSNFHRSLVLSHSNCTLICENPQAAGDDCRLLLAFAATVPLTTFSGCDQAELDNMPAVASIQAQMTVRQIYSRAEGELQDPSIHQFTAVLYGMVTKFDLDGLTSHVNRKCIACQQHIPRNLQDCASDACQQYFSLDNDEPRSISYFNINIHLSDQTGTLVEARLAGHPAERILGLRAEDFERLAEREKSELKWRFLLKYFEVRLMIKKPVGVRNHLVIVVVDMQAIPLEKLVANMVVF
What is the function of this protein?
Single-stranded DNA-binding protein required for meiosis.  May be involved in the resolution of recombination intermediates into crossovers in the meiotic recombination pathway.
What are the official names of this protein?
Protein hold'em.
What is the protein family that this protein belongs to?
Belongs to the MEIOB family.
Protein: FEX1_SCHPO
Sequence: MLLTQSYFCIMSMLGTLARLGLTALNTYPGAPFSGLLWVQFVGCVIMGFCQTESVFFPRPKHNATFLLAITTGFCGSLTTFSSWMLQMFTGMANLDPFERRGRGYSFLSVVSDFMVTMCIAMSSLIWGKQIGKTTGQWRIGKVAFAWPIPAHTHIVVRVLLLLLSICFFVGAAFYTAYTTNVTHRGIGFSLIFSPFAALTRLYLARFLNSPQYFIPYGTLCANVFATLLLSIMYMIPQITHCTPVSRSVMYGIQNGFCAVLSTLSTFSNELHTMPIKRAYIYCIISVAISFSICVIVDGATAWGHGYTEKY
What is the function of this protein?
Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
What are the official names of this protein?
Fluoride export protein 1.
What is the protein family that this protein belongs to?
Belongs to the fluoride exporter Fluc/FEX family.
Protein: ENOPH_CANTT
Sequence: MTIDTVILDIEGTVCPITFVKDTLFPYFLTKLPSILSSIEFPLSTSSSTNDDPIIQILKQLPESITISNESVFSYLKNLVDQDIKDPILKSLQGYIWEKGYEIGDLKAPIYKDSIKFIENFNKKIYIYSSGSIKAQILLFGHAEKDQESINLNPFLKGYFDITTAGFKNKSESYIKILNEINKSNDPSSVLFLSDNVNEVKSAIESGMNSYIVIRPGNAPLSDDDKSTYKTIHSLDELTL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSAB_DIOEL
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFESWIQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGAIGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLCLSAISLIAGWLHLQPKWKPSLSWFKNAESRLNHHLSGLFGVSSLAWAGHLVHVAIPGSRGEYVRWNNFLNVLPHPQGLEPLLTGQWNLYAQNSDSSSHLFGTSKGAGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFLFLVAGHMYRTNFGIGHSIKDLLEAHIPPGGRLGRGHKGLYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTNGPAFNAGRSIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL2_CAMJJ
Sequence: MAIKTYKPYTPSRRYITGLSSEDITAKPSVRSLLVKLPVHAGRNSYGRITSRHKEAGAKKLYRIIDFKRRKFGIEGKVEAIEYDPYRNCRIALIAYKDGEKRYILQPRGLSVGDIVAAAESGLDIKPGNAMKLKNIPVGTIVHNVELKPGKGGQMIRSAGAYAQLMGKEEKYVILRLASGEMRQVLAECMASIGEVGNEEWANVTIGKAGRNRHRGIRPQTRGSAMNPVDHPHGGGEGKKNSGRHPVTPWGKPTKGAKTRRKKASDKLIISRRKGK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HCHA_ECOSE
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDIAGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS20_SCHPO
Sequence: MGVNSSKINDKDRSILSIKEQRDKLLRYSKRLEKIEQLEIDIARKCLRDSDKRGALRALKAKKLYSGLITQTYGQLGNIEQLLSTIEFTLIQKDVMFGLQEGTNLIRQLQADMPLERVGRICNDRDEAMSYVDEVNDMLQGRMSRDQEDEIQEELDSLIREQEDEKVKDLEKPGFTPSTGVDVLPSVPLKNAIPSLDESFPKAASVSNTSSAVVIDEELRKDPVLG
What is the function of this protein?
Class E VPS protein implicated in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles.  The lumenal sequestrated membrane proteins will be targeted into the vacuole after fusion of the endosome with the vacuole.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 20.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Cytoplasm, cell cortex.
Protein: DPOL_BPSP2
Sequence: MKTLSIDIETFSSVDLLKAGVYAYTEAPDFEILLFAYAFDDDPVKIIDLAQGDTLPHEVLVALTSSKVIKTAYNANFERTCIAKHFNLMLLPAQWRCTAVHATTLGLPGNLDGVAKALKLSAQKDKAGKALIRYFSVPCKPTKANGQRVRNLPEHDPEKWEKFKVYCIQDVEVERAIKNRISKFEPLESEHKLWALDQEINDRGVRIDVDLVKHAIACDEQYQAGLIAEAKKLTGLPNPNSTAQLKKWLEEKGLTISSLAKDKIEELIENTNDETVHRVLRLRQEMAKTSVKKYLAMEKALCPDNRVRGLLQFYGASRTGRWAGRLVQVQNLPQNKIEDLDTARNLLKGGHYEAIELLYGQVPFVLSQLVRTAFIPSEGNEFYVSDFSAIEARVIAWLAGEEWRLEVFNTHGKIYEASAAQMFKVPVESITKGSPLRQKGKVAELALGYQGGKGALIQMGALNMGLAEGELPELVKAWRTANKKIVKFWYDVEAAAIKAVKERKPVKLQHGLTFLYESGILFVQLPSGRRLAYAKPKLELDERFGKEALTYEGKLESGKWGRLNTYGGKLVENIVQATARDCLAITLMRLDNAGYKTVMHVHDEAVLDVPRGKNELDKVEAIMGEPISWAKGLPLTADGFVTDYYKKD
What is the function of this protein?
Replicates the viral genomic DNA.  This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'-5' direction.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: YDJH_BACSU
Sequence: MRGFFGKAIFVVLAVFIMMPLLGIEAVRASELQQHVYDRAHLLSKAEIGKLESLSAKLGAKRDTDFIIITTKSTNGEDIADYTGDFYDRYGKGSTAILTIDMTNREVFIAGFKKAEQYLDNSRLNSIRNTISSDLSNENYFEAFETYIQLSYKDMGIKPGVNPDNIFFTWWFQLIAAIAVGGIAVSIMLYHAGGKVTVNGSTYMDQRTSDVIDQYDTYIRTTVTRERKPSDKDSGSDGGVTKGGTSYSGSRGSF
What are the official names of this protein?
UPF0603 protein YdjH.
What is the protein family that this protein belongs to?
Belongs to the UPF0603 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.