PharMolix/UniProtQA huggingface dataset:
Protein: GCFC2_HUMAN
Sequence: MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRAQVAGLPHRVRGPRGRGRVWASSRRATKAAPRADEGSESRTLDVSTDEEDKIHHSSESKDDQGLSSDSSSSLGEKELSSTVKIPDAAFIQAARRKRELARAQDDYISLDVQHTSSISGMKRESEDDPESEPDDHEKRIPFTLRPQTLRQRMAEESISRNEETSEESQEDEKQDTWEQQQMRKAVKIIEERDIDLSCGNGSSKVKKFDTSISFPPVNLEIIKKQLNTRLTLLQETHRSHLREYEKYVQDVKSSKSTIQNLESSSNQALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALLLKQAMTFMKRRQDELKHESTYLQQLSRKDETSTSGNFSVDEKTQWILEEIESRRTKRRQARVLSGNCNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQNILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSVEEFMDSSVEDSKKESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVILEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFWSGLKLFRNILLWNGLLTDDTLQELGLGKLLNRYLIIALLNATPGPDVVKKCNQVAACLPEKWFENSAMRTSIPQLENFIQFLLQSAHKLSRSEFRDEVEEIILILVKIKALNQAESFIGEHHLDHLKSLIKED
What is the function of this protein?
Involved in pre-mRNA splicing through regulating spliceosome C complex formation (PubMed:24304693).  May play a role during late-stage splicing events and turnover of excised introns (PubMed:24304693).
What are the official names of this protein?
Intron Large complex component GCFC2, GC-rich sequence DNA-binding factor, GC-rich sequence DNA-binding factor 2, Transcription factor 9, TCF-9.
What is the protein family that this protein belongs to?
Belongs to the GCF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: LIPB_FRATH
Sequence: MNNIYQKDLGLQQYTKVFEDMLEFTSTRTPETNDEIWLVEHPAVFTQGKHGKPEHILNSHNIPIVATDRGGQVTYHGPGQAVIYFLLDIKRNKLGAKKLVTTVEQACINMLDKYYNLKAHIIDGAHGIYINNQKIASLGLRIKQGKSYHGIAINTNMDLTPFSYINPCGYSGLKMCQLANFYQEADIKKVQQQYTAEFVTLLNNSI
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPB2_YEAST
Sequence: MKLDIKKTFSNRSDRVKGIDFHPTEPWVLTTLYSGRVELWNYETQVEVRSIQVTETPVRAGKFIARKNWIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWSLGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDGTLKIWNSSTYKVEKTLNVGLERSWCIATHPTGRKNYIASGFDNGFTVLSLGNDEPTLSLDPVGKLVWSGGKNAAASDIFTAVIRGNEEVEQDEPLSLQTKELGSVDVFPQSLAHSPNGRFVTVVGDGEYVIYTALAWRNKAFGKCQDFVWGPDSNSYALIDETGQIKYYKNFKEVTSWSVPMHSAIDRLFSGALLGVKSDGFVYFFDWDNGTLVRRIDVNAKDVIWSDNGELVMIVNTNSNGDEASGYTLLFNKDAYLEAANNGNIDDSEGVDEAFDVLYELSESITSGKWVGDVFIFTTATNRLNYFVGGKTYNLAHYTKEMYLLGYLARDNKVYLADREVHVYGYEISLEVLEFQTLTLRGEIEEAIENVLPNVEGKDSLTKIARFLEGQEYYEEALNISPDQDQKFELALKVGQLTLARDLLTDESAEMKWRALGDASLQRFNFKLAVEAFTNAHDLESLFLLHSSFNNKEGLVTLAKDAERAGKFNLAFNAYWIAGDIQGAKDLLIKSQRFSEAAFLGSTYGLGDDAVNDIVTKWKENLILNGKNTVSERVCGAEGLPGSSSSGDAQPLIDLDSTPAPEQADENKEAEVEDSEFKESNSEAVEAEKKEEEAPQQQQSEQQPEQGEAVPEPVEEES
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
What are the official names of this protein?
Coatomer subunit beta', Beta'-coat protein, Beta'-COP.
What is the protein family that this protein belongs to?
Belongs to the WD repeat COPB2 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: EIF3K_DROYA
Sequence: MSHLVKMENGQSQTIQEMLGCIERYNPDHLKTLEAYVQDQAKNNTYDLEANLAVLKLYQFNPHMLNFDITYTILLKSLTSLPHTDFVMAKCLLLPQQMKDENVQTIIDLADILERADFTLFWQRAEVNRSMFRHIAGFHDSIRKFVSHVVGTTFQTIRKDLLKELLGGIEDSTLESWIKRNGWKHQGQGLVVVAMQDDKIKTKNITEKIEFDNVGGLMAQCL
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_GLUOX
Sequence: MSDTQAAEPLAEPAAEPTGLNRWALRIEYDGTGYLGWQKQNDGTSIQGLIEAAASKLVRNRPVPSITAGRTDAGVHAAGMVIHLDFPDDAPIDARQIRDGMGYHLKPHRVVVLETAKVGPEWNARFSATWRSYRYTILNRPARPGLMENRVWHIKRPLDVDLMQQAANHLLGPHDFTSFRAVACQARSPIRTLDVLNIHRDGELVMIDTKARSFLHHQVRNMAGTLMMIGSRQWPVEKIIEILEAKDRCAAGQTAPPEGLCLMDVGYPDDPFNRS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL20_MESH2
Sequence: MRVKGGSTTRQRRRRWLKLAKGYWGHKSIGFKTAKQAVVKSWTYAFRDRKQRKRDFRKLWISRINAAARNQGISYSQLMHKIKQSNIEINRKMLAEMAIHHQSDFENIVKLAIAKSA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: LIPA_LEPBL
Sequence: MINPLKKKPRTHFLQKAPEKPDWLKVKLTFPDPKNNPVAIVRNSLEKKKLNTVCESASCPNLNHCWSRKTATYMLGGDICTRRCSYCDVASGKPSALDRDEPKRVAESAIALGLKHVVITAVNRDDLEDGGAAHFAETVEVVREGLPDCKIELLVPDFKVRPESLEIIFQCKPDIFNHNVETIKRLFPEVAPQKKYERSLDVLKIASEKGFLTKSGLILGMGETVEEVKECMRDLIGVGVSLLTLGQYLQPTPTHLPVKSYVLPEVFQELRIYGKSIGFKGVFSGPLVRSSYHADEQVSWNP
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_LEPBL
Sequence: MAKEKFDRSKPHLNVGTIGHVDHGKTTLTAAITTTLAKAIGGKNKAVAYDQIDNAPEEKARGITIATSHQEYETNNRHYAHVDCPGHADYVKNMITGAAQMDAAILVVSATDGPMPQTKEHILLARQVGVPYVIVFINKADMLAADERAEMIEMVEMDVRDLLNKYNFPGDTTPIVYGSAVKALEGDESEIGAPAILKLMEALDTFVPNPKRVTDKPFLMPVEDVFSITGRGTVATGRVEQGVLKVNDEVEIIGIRPTTKTVVTGIEMFRKLLDQAEAGDNIGALLRGTKKEDIERGQVLAKPGSITPHKKFAAEVYVLTKDEGGRHTPFINNYRPQFYFRTTDVTGVCNLPNGVEMVMPGDNVSLTVELISPIAMDKGLKFAIREGGRTIGSGVVVDIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_BARBK
Sequence: MRRTLVLVRHGQSEWNIKNLFTGWKDPDLTEKGRTEAITAGKNLKKAGLKFDIAYTSALQRAQKTAQHILEQMAQPDLQLIKNSALNERDYGDLSGLNKDDARQRWGQEQVHIWRRSYTIAPPNGESLRDTGARVWPYYFHHIQPHILRSQTVLIVAHGNSLRALIMVLEGLSSEEIVLQELATGVPIIYEFNADSTILSKKIIQS
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: UP05_PINHA
Sequence: LRCTFGRTVK
What are the official names of this protein?
Unknown protein 5.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: HFOB_METFO
Sequence: MELPIAPIGRIIKNAGAERVSDDAREALAKALEEKGETIATEAVKLAKHAGRKTVKASDVELAVKRL
What is the function of this protein?
Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils.  Increases the resistance of DNA to thermal denaturation (in vitro).
What are the official names of this protein?
Archaeal histone B.
What is the protein family that this protein belongs to?
Belongs to the archaeal histone HMF family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: ACADM_BOVIN
Sequence: MIALFRRSCGVLRSLSHFDWRSQHTKTALQREPGSGFSFEFTEQQKEFQATARKFAREEIIPLAAEYDKTGEYPVPLIKRAWELGLMNTHIPESCGGLGLGTFDSCLISEELAYGCTGVQTAIEANSLGQMPVIIAGNDQQQKKYLGRMTEEPLMCAYCVTEPVAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPASKAFTGFIVEADTPGVQIGRKELNMGQRCSDTRGIVFEDVRVPKENVLIGEGAGFKIAMGAFDKTRPPVAAAAVGLAQRALDEATKYALERKTFGKLLIEHQGISFLLAEMAMKVELARLSYQRAAWEVDSGRRNTYYASIAKAYAGDIANQLASDAVQIFGGNGFNTEYPVEKLMRDAKIYQIYEGTAQIQRLIIAREHIGRYKK
What is the function of this protein?
Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats.  The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA.  Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).  Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 6 to 12 carbons long primary chains.
What are the official names of this protein?
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial, MCAD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CPDP_YERPE
Sequence: MKYLSIKSASDKIKSGLLKTGVILSFSLFSSLSTAAFEVVALGVDGGVSDGNLTSYLIRNDSQPLYLGLDAGSVLPGIARALEKGHFAAITDAMAAPLTRQGYIFRQSINSYFISHAHLDHVSGLIIGSPDDSKKTIYASADTIDVLRNYYFNWRVWPNFTDSGSGARLGTYRMQVVRPAQSLSLGLTRLTGEMYPLSHDKSPSSMLLISSNNEFFAYFGDTGPDDVEKSKNLDTVWRKLAEKVTQQQLKGMIIEVSYPNDVADNKLFGHMTPTWLLKELKKLEQYSGEGQPLKGLPVVISHIKPSFQQGQDVRKLILSELQQGNDMGIEFILMEQGDSQKFQ
What are the official names of this protein?
Probable 3',5'-cyclic-nucleotide phosphodiesterase, 3':5'-CNP, PDEase.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-II family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ACCA_NEIMA
Sequence: MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKSNDLTKSIFSKLTPAQISQVSRHPQRPYTLDYIEALFTDFEELHGDRHFADDYAIVGGLARFNGQSVMVVGHQKGRDTKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDTPGAYPGIGAEERGQSEAIGKNLYELTRLRVPVLCTVIGEGGSGGALAVAVGDYVNMLQYSTYSVISPEGCASILWKTAEKAADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDFGQTMKNVKAVLEKQLHEAQSIPLADLLSRRFDRIMAYGKFSEQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB2_RHILO
Sequence: MAQPPIRIAIAGALGRMGRQMVEAVQADPRLALAARFHRPDSVGDGLVSRDEALAMADVVIDFTTPAASADLARVSANRGGPALVIGSTGFDAAELADIADAAKTVPIVRSGSFSLGLNMLVGLVEQAARAFAPEDWDAEIFEAHHRHKIDAPSGTALMLGQAVAGGRGAELDAVARRVRDGVTGARPPGEIGFAVVRGGSIVGEHSVSFCAEGELVTLSHAAGDRIMFARGAIAAALWVSGRPPGEYDMRDVLGFDR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase 2, HTPA reductase 2.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_XANOR
Sequence: MSTPTQSLQVKLLDPRFGDLWPLPAHATESSAGMDLRAALEAPMTLQPGDAALIPSGIAIHLADPQLCAVILPRSGLGHRHGIVLGNGTGLIDADYQGPLLISTWNRGREAFTIEPGDRIAQLVILPIVRAGLQVVDTFVDSARGAGGFGHTGVR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL9_ACIAC
Sequence: MQIILLDKVVNLGNLGEIVKVKDGYARNFLIPSGRARRATEANKAEFEAKRAELEKAAAAKLAEAQAQGEKLGGTTVKLTQKAGVDGRLFGSVTNHDIAEELNKQGYKIAKSQVRLPSGPIKTVGDSTVSVALHTDVVVEVTVSVYGETA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: APOD_BOVIN
Sequence: MVPVLLLLPALAGLFGAAEGQAFHLGKCPHPPVQENFDVNKYLGKWYEIEKIPVSFEKGSCIQANYSLKENGNVEVINKELRADGTVNQIEGEATPENITEPAKLAVKFFWFMPSAPYWVLATDYENYALVYSCTTIIWLFHMDHVWILGRNPYLPPETVTYLKDILTSNNIEVEKMTITDQVNCPESM
What is the function of this protein?
APOD occurs in the macromolecular complex with lecithin-transport and binding of bilin.  Appears to be able to transport a variety of ligands in a number of different contexts (By similarity).
What are the official names of this protein?
Apolipoprotein D, Apo-D, ApoD.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GERIA_BACCE
Sequence: MIWNWLRKKKKSNTSKLNETDNQEQHSNNQEDDNKEQTRSMKHNKGKNNEQKDSSQDKQQSAKQGDSSQDKQQNPKQEDSSQDKQQNPKQGDSSQDKQQSAKQKDPSQDKQQNPKQEDSSQDKQQSAKQGDSSQDKQQSAKQGDSSQDKQQNAKQDEPSQSKQQSSGGNSIYDFTKPEKDRIHSLQNLIEKLKKSSDFVNYHTSDDETMPYWISYYRPSLDGEKLQKYLMPTLLERPNASLEELKEHIPMSGITITNDLQKIEDMVLKGHAIIQLNQQDQKCMLANIAIDNYRAPTPPLNESTVIGPQEGFVEDIDTNINLVRKRLPVLDLQTKEMIIGEFSKTKVVMMYLDNLAEKDNVDFLEESLRALEYDQINDSAYLQELMGEKSIFPLYINTERTDRVTKALIDGKIAIFVDGSPSVLLTPVSYFDFFISPEDYNVSWMYATFSRILRLIAVLFSICATPLYVAVLNYHYELIPSDLLETLILSRAQVPFPPLIEALFLELAIDLLREAGARLPMKVGQTLGIVGGIVIGQASVQAGLTSNILLIIVALSALASFITPIYKMGNAVRLLRFPFLAFAEIGGLFGISLGFIFLFTHLFRLTSLRKPYALFYPTRQQSVKDSWIRFPLTMIDTRDVQARPQHVKKAAKGISTKHRSDFDD
What is the function of this protein?
Required for inosine germination.
What are the official names of this protein?
Spore germination protein GerIA.
What is the protein family that this protein belongs to?
Belongs to the GerABKA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTU_LIGS1
Sequence: MAKEHYERTKPHVNIGTIGHVDHGKTTLTAAITKVLAEKGLAEASDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLARQVGVEYIVVFLNKCDLVDDDELLDLVEMEVRDLLSEYDFPGDDIPVIRGSALKALEGDKDAEAQIMELMDTVDEYIPTPQRPTDKPFLMPVEDVFTITGRGTVASGRIDRGTVKVGDEVEIVGLKDDVVKTTVTGVEMFRKTLDEGEAGDNIGALLRGVDRTQVERGQVLAKPGSIQTHKKFKGEVYVLTKDEGGRHTPFFSNYRPQFYFHTTDVTGVIELPEGVEMVMPGDNVTFTVELIAPVAIEKGLKFTVREGGRTVGAGVVSEIDD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTIF_XENTR
Sequence: MESSSVASASSEAGSSRSLEIEELERFIDSYVLEYQVQGLLTDKTEGDGESDKTQSNVSQWTVECTERLEENRTSPRNREPTYSQNGNKEGPLDMLGTDIWAASTVESISGATWDLQPEKLDFTQLQLRQRNSPKHPPPQIDRDGFGKGKRVEGDDINLNDIEKVLPTWQGYSPLPHEADIAQTKKLFRRKRNDRRKQQKPQGGNKQPPSQQNDHQPATAKHNSREHQRQYHGNPPPPHPSGKQGHHGYSQNRRWHHNQKHLPNDLQRNAKETDTLKIEDASVCTVHIPLDIHSNTDSTERHCPPANDSEAKRKESIQSRDRPKISLLQSSKDRLRRRLKEKEDVAVESTNPQKTKMDKLIEILNSMRNNSSDVDYKLTTFMAEAQNSANSEEMLGEIVKTIYQKAVTDRSFAHTAAKLCDRMALFMVEGTKFRSLLLNMLQKDFSIREEMHRSDVERWLGFITFLCEVFGTMRSNMAEPFRVLVCPIYTCLRELLQSEDVKEDAVLCCSMELQSAGRLLEDQLPEMMSELLATARDKMLCPSESMLTRSLLLEVIELHANSWNPLTPTITQYYNKTIQKLTG
What is the function of this protein?
Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC).  In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E.  Also required for nonsense-mediated mRNA decay (NMD), the pioneer round of mRNA translation mediated by the cap-binding complex playing a central role in nonsense-mediated mRNA decay (NMD) (By similarity).
What are the official names of this protein?
CBP80/20-dependent translation initiation factor.
What is the protein family that this protein belongs to?
Belongs to the CTIF family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: KDSA_METPP
Sequence: MKLCGFDVGLDRPFFLISGPCVVESEQLQMDVAGRLKEITAALGIPFIFKSSYDKANRSSGTSFRGPGMEKGLEILAKVRRDLQVPVLTDVHSEAEIPVVAQHVDVLQTPAFLCRQTDFIRAVAQSGKPVNIKKGQFLAPGDMKNVIQKARDAAREKGLPDDVFMACERGASFGYNNLVSDMRSLAIMRETGSPVVFDATHSVQLPGGQGTSSGGQREFVPVLSRAAIAVGVAGVFMETHPDPAKALSDGPNAVPLKHMKALLEQLVSIDRVIKAQPLLENDFSC
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPXH_BACCZ
Sequence: MDKQEAKHINMPSPSTCEHKSVEAYLFIDPLCKDCWEIEPFIIKLWLEYGKYFSIRHIVTGKVDGTNASSHKWNKPANIRFVWEKTTSLHGFSCDGKVHMQEASSTPYLVSMAIKAAELQGRKAGSKFLRKLQEYIFLENVSNPDCELLLACAKDSDIDVEEFKKDLYSASAKKAFQCDLKFTNEMHITEIPSLVFFHANSDEEGIKIAGTYSYDVYVQLLKELVKCEIEPEPLPPLEVLLEATQFISSKEVAFIYDCSKQEIERELKKLQLKRKVQMIDVKCERYWKWIAKEKDLV
What is the function of this protein?
Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions.  Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
What are the official names of this protein?
ClpXP adapter protein SpxH.
What is the protein family that this protein belongs to?
Belongs to the SpxH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_DROSE
Sequence: MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGRVFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEAKTIDGYLLRVFCIGFTAKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDSIAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDVSKLLELHGDGGGKSVEAVVSSEGAVIDRPEGYEPPVQEAV
What is the function of this protein?
Essential for oogenesis; required for late follicle cell development.
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_CHESB
Sequence: MAKNTNITTVADNRKARFSYEVIDTLEAGLVLSGTEVKSLREGHANIQESYAAVEGGEIWLINSHIPEYFAGNRFNHEPRRRRKLLLSKKEMARLAQAVEREGMTMVPLKLYFNERGIAKLLLAIARGKKLHDKRETLKQRDWSREQARLLKERG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RNPH_ANADE
Sequence: MRKNGRGPLDLRPILLEPRVSKHAEGSCLVRFGDTHVLCTASVDEKVPPHVYGTGAGWVTAEYGMLPRSTHERMQREAARGKQTGRTLEIQRLVGRALRAAVDLRAIGPRTVTLDCDVIQADGGTRTAAITGAYVALVQAVRSIQKRKQLAHDPVKRSVAAVSVGIVAGEVHLDLDYDEDSTAEVDMNVVATGEGALVEVQGTAEGKPFARAELDRMLDAALAGLSRLKELQEAALRTP
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: Y6559_BACAN
Sequence: MDFQDIIFLMMDIKIEIYQDEKDMEKTEVAVKTEKTAIPFKWENPLEDTYTKMGYSESSPISAGGTFMG
What are the official names of this protein?
Uncharacterized protein pXO2-52/BXB0059/GBAA_pXO2_0059.
Protein: RS3_METVS
Sequence: MIERTFIAENVSETLIDEYFKGKLVRAGYSHLELKKTPIGTRITVFAEKPGFVIGRKGKMVKELTDTLTEVYKVENPQIEVKPLETPDLDPAIVGHKIAASLEKGMHFRKTAHSAVRRVMAAGAKGVAIIISGKLSGERSRTEKFMDGYMKHCGEPAEELVIKSHQLAKLKLGIVGVTVKIMRPDVSLPDEIIILSGEIKEVTEFSEVSQE
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RS15_SHEDO
Sequence: MSLSTEAKAKILADFGRCENDSGSTEVQVALLTAQINHLQGHFKTHIHDHHSRRGLLRMVSARRKLTAYLKRTDNARYTALIQKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.