PharMolix/UniProtQA huggingface dataset:
Protein: LIPB_BURP0
Sequence: MPSAPAAPDAAASVAPNPPAALPVTVRWLGETPYDACFDAMRAFTDARTPDTDDEIWVVEHPPVYTLGQAGNPAHLLVADSGVPLVKVDRGGQITYHGPGQIVAYLLVDLRRRKLMVRTLVTRIEEAVIETLAAYNLASARKAGAPGIYVESGPHRGAKIAALGLKIRNGCSYHGLSVNVKMDLRPFLAINPCGYAGLETIDMASLGATADWHEVAQTLVRRLIAHLDGATAAAALPQQALEQSND
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_SCHJY
Sequence: MSGLMFRFPFRRFVATMPDKTKYIAKSGTYPKGFLINGVSSGVKAKGALDLTMLVSEKPCNAAAVFTKNAFQAAPVRVSRETLQQTKGQGIQCLVVNSGCANAVTGSGGVQDARLITALADKAVLGRGDGGLPSTLVMSTGVIGQRLKMDKISSGVMKAIEGLGSSHEHWMRGAKAICTTDTFPKVVSQEFSVNGQTYRIAGLAKGAGMINPNLATLLGFFATDAPVAVEAVQQILREAVDKSFNAISIDGDTSTNDTIAFLANGASGGPEIDVSSPAYEELKQSVTGIAQKLSQLVVRDGEGATKFVTIRVRGAATEADAKLVAATISNSALVKTAFFGEDANWGRILCAIGYSGAIVNPKATSVSFVPADQTESLRLLVLGEPQNVDEERASEILSHDEFGLDVDLGSGNHETVSWTCDFSYEYVRINADYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y1285_CHLL3
Sequence: MGMPNFGDMMKQIQQAGEKMQDVQKQLEKLVTSGEAGGGMVKVTVNGKQRVLSLWIDPEIMDDAEMVQDLVLAAVNSALEASGRMAQEEISKVAGGMINPQDILKNLGQ
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Plut_1285.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: 148R_ASFB7
Sequence: MKKIFLTMTPLPYMNHLPENHYFLSLTVVISIIHLFTTCVPQHNHSTHFPYLNHARHLNHVLHPSHARHPNHVLHLNRVLHPNRVVHLNHVLHLNHVLHLNHVLHLNHVLHPNHVLHLNPILHPNHYLVSRYYPISRHYLHKIFRLFM
What are the official names of this protein?
Uncharacterized membrane protein EP148R.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: PRM3_MOUSE
Sequence: MGSRCAKLSTGHGPAQNTGHSRGHESSMKKLVACVSQDNFSLSSEGEEEEEDEEEEEEEEEEEEEEQIPVKGKLLLLEPEKQESAEDGEAQPSPEPKQTHS
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-3, Sperm protamine P3.
What is the protein family that this protein belongs to?
Belongs to the protamine P3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS20_STRA3
Sequence: MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELYRAASSSIDKAASKGLIHTNKASRDKARLATKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: DDL_HALOH
Sequence: MSKLRLGVLFGGRSQEHEVSVMSARSVVKMAKKEKYKVIPFGITKKGQWVGPEESWNILNNGINEVKASKDRCITESVRVFLDHKLDIVFPVLHGPYGEDGKLQGFLDCLDIPYIGASVLSSAAGMDKEIMKNLFSYHKIPQARYRVYRQNHLENGLDGIISEIDRFLGWPCFVKPANMGSSIGVSKVHSPGEVKKALEKGFYYDRKLIFEEFVEGREIECSVLGNDQVEASLPGEILPGKEFYDYEAKYKDNKTRLVIPASLDESVIDKARNLAIKAFKAIDGNGFARVDFFLKNNGVLLVNEINTIPGFTQYSMYPKLWEATGLNYPDLIDKLIELALEDR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_PSEP1
Sequence: MAAITAALVKELRERTGEGMMDCKKALEKAGGDIEKAIDDMRASGAIKAAKKAGNVAAEGAIAVKTDGTSAVLLEVNSQTDFLALQDDFKNFVAESLEEAFAQKLTDAAPLIASREAAREALVAKCGENVNIRRLVRVEGDVVGAYLHGNKIGAVVVLKGGDVELAKNIAMHVAASNPEFLDSSEISAEAIEREKNVFLQLNADKIAGKPENIVENMINGRITKFKAEASLKEQAFVMNPEVKVGELAKKAGAEIVSFTYFKVGEGIEKPVDDFAAEVAAQVAAAKQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_FRATW
Sequence: MLLDDLYEIVEPITADLGYILWGIEVVGSGKLTIRIFIDHENGVSVDDCQIVSKEISAVFDVEDPVSGKYILEVSSPGMNRQIFNIIQAQALVGFNVKAVTLAPVGSQTKFKGVLERVEGNNVILNLEDGKEISFDFDELKKLRVSPDFS
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF_TRYBB
Sequence: MSWQSYVDDSLVGSGFMHSAAIVGLADGSYWAYGGTYVPQPEEVTHILKCLENFSLVQSSGVTICGVKFFGLQSGSEGQMKYIFFKKGAAGGCIYTSKQTAIIAVYGNPGDASALQQDLQKTEATYVAVNPADCNTTVKRIAEYLISLDY
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: APT_RUBXD
Sequence: MNITERTIQVIRNRIRSVPDYPSPGVVFRDITPLMEDGPSLHAAVDALAEATRSLDYDRVISAEARGFVFGTALAYRSRKGLVLARKPGKLPREVISVSYELEYGTDSLEVHADAIPPGTRVLVADDLLATGGTARAMCELVEKSGGSVAGCAFLIELGFLEGRKKLLAGYDVISLINYHDPAAE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIT2_YEAST
Sequence: MKFSTIFGATTVMTAVSAAAVSSVMTTKTITATNGNNVYTKVVTDTADPIISYSTTRTVVVSNSDATYTKVVTEGPDTTSEKSTTKTLTLTNGSGSSTNLYTKTVTQAVESSTSSSSSSSSSSSSASSSGAAPAAFQGASVGALALGLISYLL
What is the function of this protein?
Involved in the uptake of non-siderophore and siderophore sources of iron.  Has a role in the retention of iron in the cell wall and periplasmic space.
What are the official names of this protein?
Facilitator of iron transport 2.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Protein: SEM1A_DROME
Sequence: MLNSHNTNHNNNSASNSNYNKGHKMHLKSATAKATIMKHKLSKFYGYGWMQVFLLLTVLVIGNQSAWQENIRPKLYVELGPEDVLKFVGNESVVDHFKLVTKDGNSLLIGARNTVFNLSIHDLVEQQRLVWTSPEDDTKMCLVKGKDEEACQNYIRIMVVPSPGRLFVCGTNSFRPMCNTYIISDSNYTLEATKNGQAVCPYDPRHNSTSVLADNELYSGTVADFSGSDPIIYREPLQTEQYDSLSLNAPNFVSSFTQGDFVYFFFRETAVEFINCGKAIYSRVARVCKWDKGGPHRFRNRWTSFLKSRLNCSIPGDYPFYFNEIQSASNLVEGQYGSMSSKLIYGVFNTPSNSIPGSAVCAFALQDIADTFEGQFKEQTGINSNWLPVNNAKVPDPRPGSCHNDSRALPDPTLNFIKTHSLMDENVPAFFSQPILVRTSTIYRFTQIAVDAQIKTPGGKTYDVIFVGTDHGKIIKSVNAESADSADKVTSVVIEEIDVLTKSEPIRNLEIVRTMQYDQPKDGSYDDGKLIIVTDSQVVAIQLHRCHNDKITSCSECVALQDPYCAWDKIAGKCRSHGAPRWLEENYFYQNVATGQHAACPSGKINSKDANAGEQKGFRNDMDLLDSRRQSKDQEIIDNIDKNFEDIINAQYTVETLVMAVLAGSIFSLLVGFFTGYFCGRRCHKDEDDNLPYPDTEYEYFEQRQNVNSFPSSCRIQQEPKLLPQVEEVTYAEPVLLPQPPPPNKMHSPKNTLRKPPMHQMHQGPNSETLFQFQPDGYNTQQSYRGRDNFGTLRSHQVMGDNYRRGDGFSTTRSVKKAVNNTNTRNRSLGRARRQPPRHGIVTQHRSNSPQQQQQQSQQPHSSSGSSPVMSNSSSSPAPPSSSPSPQESPKNCSYIYRD
What is the function of this protein?
Involved in growth cone guidance through its role in axonal repulsion.
What are the official names of this protein?
Semaphorin-1A, Semaphorin-I, Sema I.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OPGC_SHIFL
Sequence: MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTLD_BUCAP
Sequence: MRALHFGAGNIGRGFIARVLLKSDFNLIFSDVDQNIINAINNYKKYKIKLIDNSFEKIININNISAINSYDPNVLNVISHVDLITTAAGVNALYKIASILIEGIILRINLKCKKPLNIIACENKIKATSFLKKIIFDKIPLKYHDYFDEYIGFVDCTIDTIVPTFSSFKEENSLFVIAENFKEWIVDVNQFKGMVPKIIDMTLSDNLTSFIDRKILTLNTGHAIAAYLGLMKNYKNICEAMSDFSIQRIVKDAMYESGLVLIKRYNFNKKDHLSYIDKIFVRFKNPFILDKLERIARNPLQKLSKDERLIQPFVEAMKYNLPYFNLVKGIAAALHYRNINDIQSIKLSSLIKEEGLEETLVKVCKLNANSNEIRIIISEYHSIIKDFL
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: TRMFO_STRPQ
Sequence: MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDREGYAKSVTAELENHPLIEVIRDEITEIPNDAITVIATGPLTSDALAEKIHAVNGGDGFYFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLTETFQSRSNPNLLFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGSLPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM_RHIME
Sequence: MSWSAAQYAKFEDERTRPARDLLAQVPDLPAGPAFDLGCGPGNSTELILARFPGSPLTGIDSDDDMLSAARTRLPDLRFERGDLAAWTPPAESALFFANAVFQWLPEHVTLFERLILALAPGGTLAVQMPDNLDEPTHLLMEETAEESAFAPAFAGRTIRRRSLPSPATYVERLASKEVRVDVWHTVYYHQLANANAIVEWVKGTGLRPYLDALPTTQRAGYLAAYAEKIRKAYPAMKNGRVLLRFPRLFIVATRNL
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_MYCPN
Sequence: MQNKTVFVGISGGVDSAVSALLLKQQYREVIGIFMECWDNTLNNDQLGHRAFNEHKSGCSSKEDFREAQAIAQLLGIKLIKQNLVEPYWKQVFLPTIDAFKNGLTPNPDMLCNRLIKFGLMRDYCKQLDPNSDFATGHYAALSWDNNQPLLAIPKDKHKDQTYFLAHVKPAQLQDVVFPLAHLLKTEVRQIALAHHFSVATKKDSTGICFIGERHFSDFLKNYLPVKPGVIYDWKTQRQLGSHEGVWFYTTGQRSGLNLGGQAARNFVVEKDLKTNTLYVSSDPEDLQRRGITLSHFNWLYQPNPLTQTVLVRIRHAQPLVQGHITVQPNNVVQVQLDQPIDRVTNGQYGVLYTQNGICLGSGIITASQI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARA_STAAR
Sequence: MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
What is the function of this protein?
Global regulator with both positive and negative effects that controls the expression of several virulence factors and the biofilm formation process in a cell density-dependent manner.
What are the official names of this protein?
Transcriptional regulator SarA, Staphylococcal accessory regulator A.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTF77_ARATH
Sequence: MADKYIVEEAEALAKRALHSPIAQATPIYEQLLSLYPTSARFWKQYVEAQMAVNNDDATKQIFSRCLLTCLQVPLWQCYIRFIRKVYDKKGAEGQEETTKAFEFMLNYIGTDIASGPIWTEYIAFLKSLPALNLNEDLHRKTALRKVYHRAILTPTHHVEQLWKDYENFENTVNRQLAKGLVNEYQPKFNSARAVYRERKKYIEEIDWNMLAVPPTGTSKEETQWVAWKKFLSFEKGNPQRIDTASSTKRIIYAYEQCLMCLYHYPDVWYDYAEWHVKSGSTDAAIKVFQRALKAIPDSEMLKYAFAEMEESRGAIQSAKKLYENILGASTNSLAHIQYLRFLRRAEGVEAARKYFLDARKSPSCTYHVYIAFATMAFCIDKEPKVAHNIFEEGLKLYMSEPVYILKYADFLTRLNDDRNIRALFERALSTLPVEDSAEVWKRFIQFEQTYGDLASILKVEQRMKEALSGKGEEGSSPPESSLQDVVSRYSYMDLWPCTSNDLDHLARQELLVKNLNKKAGKTNLPHVPAAIGSVASSSKVVYPDTSQMVVQDPTKKSEFASSANPVAASASNTFPSTVTATATHGSASTFDEIPKTTPPALVAFLANLPIVDGPTPNVDVVLSICLQSDFPTGQTVKQSFAAKGNPPSQNDPSGPTRGVSQRLPRDRRATKRKDSDRQEEDDTATVQSQPLPTDVFRLRQMRKARGIATSSQTPTGSTSYGSAFSGELSGSTG
What is the function of this protein?
One of the multiple factors required for polyadenylation and 3'-end cleavage of pre-mRNAs (By similarity).  Required for the targeted 3' processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed:19965720).
What are the official names of this protein?
Cleavage stimulation factor subunit 77, AtCstF-77, AtCstF77, CF-1 77 kDa subunit, Cleavage stimulation factor 77 kDa subunit, CSTF 77 kDa subunit, Protein SUPPRESSORS OF OVEREXPRESSED FCA 2, SOF2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_SALPA
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PYC_MOUSE
Sequence: MLKFQTVRGGLRLLGVRRSSSAPVASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELGIRTVAVYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENGVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDSPISSLHEAHEFSNTFGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPATHLDPQLRSRLTSDSVKLAKQVGYENAGTVEFLVDKHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVSEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIPFLQNVLNNQQFLAGTVDTQFIDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVNVSPSPVDPAVPVVPIGPPPAGFRDILLREGPEGFARAVRNHQGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFNKLFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVFKFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSLEYYMGLAEELVRAGTHILCIKDMAGLLKPAACTMLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAVDSMSGMTSQPSMGALVACTKGTPLDTEVPLERVFDYSEYWEGARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQMLGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGIPHGGFPEPFRSKVLKDLPRIEGRPGASLPPLNLKELEKDLIDRHGEEVTPEDVLSAAMYPDVFAQFKDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFELNGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVAAGDKVAKGQPLCVLSAMKMETVVTSPMEGTIRKVHVTKDMTLEGDDLILEIE
What is the function of this protein?
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.  Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
What are the official names of this protein?
Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase, PCB.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KAB14_OLDAF
Sequence: GLPVCGESCFGGTCNTPGCACDPWPVCTRD
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Kalata-B14.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: END3_PICST
Sequence: MPRLEDWEIKKYWEIFQGLDPVNKKLTGDKVAPVLKNSRLQDDQLAKIWELSDIDSDGKLDFEEFCITMRLIFDMVNGVSTAIPKELPSWLIPSSKAHLIQANNAVRSNSNQGFDYEDDEDGLSDDFDWYISPTDKATYETIYNSNSDSYGRVKFESLNSLYSSLSKVPKSDISSAWNLVNPKSFETIDKDQVLVFLHILNQRENGKRIPRGVPASLRATFSKEVPNYDLNSVQAKPQPSVGTGRKSFANDYLNKIGQANTITERGTDFSSTEGTDWEEVRLRRELTDLENLLHKIQNGNKNDNSNTNDDSALLKYEYEQLLKYKQNKLSSANLSTKSKDLTEVKGDLDLIQSQVSTLEDFLKSKSSELEKLNEEIRSLKA
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein END3, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: DER_STRPZ
Sequence: MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEYVSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIVENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQRLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKPPTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: 7B2_DROME
Sequence: MLFRSQTHVFPGVYMMVAMLVVALSGYQVQSYSAKDILADVLMTDLLNRMDKDMQVGYYDVGNEAAAGSKDNVDLVSRSEYARLCDGGSDCILQSGSASGAASHPSLRDDEFLQHSSLWGHQFISGGMGEGPNRYPTIVKNDAGLPAYCNPPNPCPEGYDMETQGGSCIVDFENTAIFSREFQAAQDCTCDNEHMFDCSEQDSADVGGDKGDLNSAVEQYIMQMGQENSLNNVNSLAKKAGYPVMPDPRLDDAVINPFLQGDRLPIAAKKGNLLFH
What is the function of this protein?
Acts as a molecular chaperone for neuroendocrine convertase amon/PC2, preventing its premature activation in the regulated secretory pathway (PubMed:10749852).  Binds to inactive amon in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated (By similarity).  Also required for cleavage of amon (PubMed:10749852).
What are the official names of this protein?
Neuroendocrine protein 7B2.
What is the protein family that this protein belongs to?
Belongs to the 7B2 family.
Protein: RL14_PROMH
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYADVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDSNACVLLNNNSEQVIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SULA_SALDC
Sequence: MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALSRRQHSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: OBG_CUPNH
Sequence: MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAVADRNINTLIDFRYARKHVARNGENGRGSDCYGAAGEDITLRMPVGTLITDMDTGEVIADLTEHGQRVCLAEGGMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISHISNARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGLLLHIVDLAPFDEAVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEDERAARVKDFIKRYKWKGPVFQISALTGEGCRELIYAIKDHLQAIKAEEAAALAEPDIRLDERLHNVDQGQGEA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U74C1_ARATH
Sequence: MSEAKKGHVLFFPYPLQGHINPMIQLAKRLSKKGITSTLIIASKDHREPYTSDDYSITVHTIHDGFFPHEHPHAKFVDLDRFHNSTSRSLTDFISSAKLSDNPPKALIYDPFMPFALDIAKDLDLYVVAYFTQPWLASLVYYHINEGTYDVPVDRHENPTLASFPGFPLLSQDDLPSFACEKGSYPLLHEFVVRQFSNLLQADCILCNTFDQLEPKVVKWMNDQWPVKNIGPVVPSKFLDNRLPEDKDYELENSKTEPDESVLKWLGNRPAKSVVYVAFGTLVALSEKQMKEIAMAISQTGYHFLWSVRESERSKLPSGFIEEAEEKDSGLVAKWVPQLEVLAHESIGCFVSHCGWNSTLEALCLGVPMVGVPQWTDQPTNAKFIEDVWKIGVRVRTDGEGLSSKEEIARCIVEVMEGERGKEIRKNVEKLKVLAREAISEGGSSDKKIDEFVALLT
What are the official names of this protein?
UDP-glycosyltransferase 74C1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.