PharMolix/UniProtQA huggingface dataset:
Protein: NCER3_ARATH
Sequence: MTRWSMSMHCTLFLLFLLRLTCIFSDSDYLMGLGSYDITGPAADVNMMGYANMEQVASGVHFRLRARAFIVAEPYKKRIAFVNLDAGMASQLVTIKVIERLKQRYGELYTEENVAISGTHTHAGPGGYLQYILYLVTSLGFVHQSFNALVDGIEQSIIQAHENLRPGSILINKGELLDAGVNRSPSAYLNNPAHERSKYEYDVDKEMTLVKFVDDQWGPVARIMEDWFERENGCRSVDVESPRRVSSIISDPYDQDLMEMASSLLSTGGKTVTRMSSVARRVRSRFRHADKPRFVSAFCQTNCGDVSPNVLGAFCIDTGLPCEFNQSTCGGKNEQCYGRGPGYPDEFESTRIIGERQFKKAADLFTKASEEIQGKVDYRHAYVDFSQLEVTINGQNGGSEVVKTCPAAMGFGFAAGTTDGPGAFDFKQGDDQGNPFWRLVRNLLKNPTEEQVRCQRPKPILLDTGEMKQPYDWAPSILPVQILRIGQLVILCVPGEFTTMAGRRLRDAVKTVLKEGSNGREFSVVIAGLTNSYSQYIATFEEYQVQRYEGASTLYGPHTLSGYIQEFKKLANDLLSAQTTDPGPQPPDLLHKQISLLTPVVADMTPIGTAFGDVTSDVPRLSKFRKGADIVRVQFRSANPRNDLMTEGTFALVERWLEGRETWVPVYDDDDFCLRFKWSRPFKLSTQSTATIEWRIPETASPGVYRITHFGSAKTPISSIHHFSGSSSAFVVY
What is the function of this protein?
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid (By similarity).  Promotes oxidative stress resistance (PubMed:26150824).
What are the official names of this protein?
Neutral ceramidase 3, AtNCER3, N-CDase 3, NCDase 3, Acylsphingosine deacylase 3, N-acylsphingosine amidohydrolase 3.
What is the protein family that this protein belongs to?
Belongs to the neutral ceramidase family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum. Golgi apparatus.
Protein: PMK2_CAEEL
Sequence: MGMSATMGDSASIPGVFFADFGPAPPEITPEGYHEVELNKTKWVLPQWYNSLKPLGEGAYGVVCTAEYEPTGDRVAIKKFFRPFQSTIHAKRTYRELKLLRTLQHDNVLEMIDVFTPDPDASSLNNVYFVSVLMGSDLQNIMKIQRLTDEQIQLLIYQVLRGLKYIHSAGIIHRDLKPSNIAVNERCEVKVFLSFSQLSFLILSFFKILDFGLARAQDAEMTGYVATRWYRAPEIMLNWMHYTQTVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKIQSEEARNYIKNRSPIIRQDFVTLFPMASPYALELLEMMLILDPDRRISVSSALRHDYLREYSVPNDEPVAMDTVINSIVTIDPAEERATTLSDWRELIWNEIRLFQNSARRLSFVSCTDTEEEPMKI
What is the function of this protein?
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets.
What are the official names of this protein?
Mitogen-activated protein kinase pmk-2, Stress-activated protein kinase pmk-2, p38 MAP kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_LONMO
Sequence: MTNIRKTHPLLKILNNSFVDLPAPSSLSAWWNFGSLLGVCLTLQILTGLFLAMHYTADTATAFNSVAHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYTETWNVGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTELVQWIWGGFSVDKATLTRFFTFHFLFPFIVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLMMLTVLSTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAVMPVLHMSKQRSMMFRPLSQCLFWLLVAVLLTLTWIGGQPVEYPYVIIGQAASVLYFMILLILMPLVSIMENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PGP_METAC
Sequence: MKFKAIVIDIDGTITCENRELHLGAVKKIRILKVPVVLATGNILCYARTASKLIGLDGAVIAENGGAVTVRYDLNGTFEESLEECEKAFSFLSEYFKLTKLDPFYRKTEIALRRDFNLEKARTLLETQPFDVEMVDTKYAVHIKSTRINKGSGLRKLAEIMGLEAEDFVAIGDSENDIEMFEAAGFGIAVANGDERIKEAANYVTEASYGDGAVEAIEFLESNGWI
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: ACPS_ANAMF
Sequence: MIVGIGVDLVSVRRMQQLLERFGNRFTTRAFSEVEIRDSLQYKNAHAVARHFAKRFAAKEAYVKAVGLGFGRGIEMRGVSVFNDALGKPRIAVSGDVGHNVELSLSDDGEYAIAFVVLHV
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_DESRM
Sequence: MNAIIWENNQLQLLDQTKLPRTIEYIQCTDYHTVGKAIKKLSVRGAPAIGAAAAYGLVVGAQQVDATDRKTFLEKLEAIAGELGATRPTAVNLRWALDRMMMRLSTAPEQNVEDLRKIMLEEAHAIYNEDVESNRKMGEYGQELLPEEARVLTHCNAGALATAGYGTALGVVRAAHEKGKKVHVYADETRPLLQGARLTSWEMVQEGIPVTLITDNMAGYLMSKKMVDCIVVGADRITANGDVANKIGTYGVAVLANHHNIPFYVAAPLSTIDMSLSSGEEIPIEERDPQEVTHHGGQPMAPEGVQVWNPAFDVTPNSLVKAIITERGVVLPPFAENLAKICCNKK
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: RR4_OROMI
Sequence: MSRYRGPRFKKIRRLGALPGLTNKRPKAEKDLINQSRFVKKSQYRIRLEEKQKLRFHYGLTERQLLKYIRIAGKAKGSTGQVLLQLLEMRLDNILFRLGMALTIPAARQLVNHRHVLVNGRIVDIPSYRCKPLDIITAKDKQQSRTLIQNSLNSSPHAKIPNHLTLDLFQYKGIVNQIINSKWVGLKINEFLIVEYYSRQIKT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
Plastid 30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid.
Protein: RF2_SACEN
Sequence: MNPDVAADLKELSTTLEGIESVMDLDALRAKIAELEEEAARPDLWDDVEHAQRVSSQLVHRQSELRKIKDLRQRVEDLEVLYELSEDEGDDSGLAEADSERTKLKKDLEALEVRTLLSGDYDQREAVVTIRAEAGGVDAADFAEMLMRMYVRWAERHEYPVEVYDTSYAEEAGLKSATFRVNAPYAYGTLSVEQGTHRLVRISPFDNQGRRQTSFAGVEVLPVVEETDHVEIPEKDIRVDVFRSSGPGGQSVNTTDSAVRITHIPTGIVVSCQNEKSQLQNKAAALRVLQSKLLAKKKEQERAELDALKDSGSSWGNQMRSYVLHPYQMVKDLRTEFEVGNPDAVLDGQIDGFLEAGIRWRRQQDAA
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_PSEE4
Sequence: MSGNTYGKLFTVTTAGESHGPALVAIVDGCPPGLEISLADLQHDLDRRKPGTSRHTTQRQEPDEVEILSGVFEGRTTGCSIGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGLRDYRGGGRSSARETAMRVAAGAIAKKFLATQGIRVRGYMSQLGPIEIPFKTWDSVEQNAFFSPDPDKVPELEAYMDQLRRDQDSVGAKITVVAEGVMPGLGEPIFDRLDAELAHALMSINAVKGVEIGAGFASVAQRGTEHRDELTPEGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTPGRSIDVDGNPVEVITKGRHDPCVGIRATPIAEAMMAIVLMDHLLRHRAQNAEVKVGTPVLGQL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: MNME_YERPN
Sequence: MSTTDTIVAQATPPGRGGVGILRVSGRAASEVAHAVLGKLPKPRYADYLPFKDVDGSTLDQGIALYFPGPNSFTGEDVLELQGHGGPVILDLLLKRILALPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSAVNSLQGAFSARIHQLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEGQLNGVMADLEQVRTEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREANDEVERIGIERAWNEIEQADRVLFMVDGTTTDATEPAAIWPEFMARLPATLPITVVRNKADITGETLGLTKVNGHSLIRLSARTGEGIDLLRDHLKQSMGFTSNTEGGFLARRRHLQALETAARHLIQGHEQLVSAYAGELLAEELRLAQQSLSEITGEFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBID_RALPJ
Sequence: MQYRDLRDFLAQLERTGELRRVHQPVSPRLEMTEVCDRLLRSEGPAVVFAQPVDGAQKYDMPVLANLFGTTRRVALGMGAESLDELRDIGRLLSALKEPEPPRGLREAGKLWTMAKAVWDMAPRKVSSPACQEIVWEGNDVDLSRIPVQTCWPGDAAPLVTWGLVITRGPHKKRQNLGIYRQQVINRNQVIMRWLAHRGGALDFREHAIANPGQPFPIAVALGADPATILGAVTPVPDTLSEYQFAGLLRGSRTELATCLTPSLAQAQLQVPAGAEIILEGHIQPDPTHPSGYQHALEGPFGDHTGYYNEQDWFPVFTVERITMRRDPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFPEIADFYLPPEGCSYRMALVSMKKQYAGHAKRVMFGVWSFLRQFMYTKFIVVVDDDVNLRDWKEVIWAITTRVDPARDTVMVENTPIDYLDFASPVSGLGSKMGIDATNKWPGETTREWGQPIVMDTAVKAKVDAMWDTLFQ
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL331_MYCBP
Sequence: MASSTDVRPKITLACEVCKHRNYITKKNRRNDPDRLELKKFCPNCGKHQAHRETR
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL6_CHLAD
Sequence: MSRIGKRPITVPKGVQVTIGEQNLVTVKGPKGTLTQKLHPDMIIKQEGDVITVQRPSDEKLHRSLHGLTRTLINNMIVGVTQGWQRALEINGVGYRAQLEGKTLVLNLGFSHPVRIEPPPNISYIVGERKSANDPLSLTVVGIDKQQVGEEAARIRSLRPPEPYKGKGIKYLEEKIRRKAGKAGKAK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MET14_DANRE
Sequence: MNSRLQEIRERQKLRRQLLAQQLGAESPDSIGAVLNSKDEQKEIEETRETCRASFDISVPGAKRKCLNEGEDPEEDVEEQKEDVEPQHQEESGPYEEVYKDSSTFLKGTQSLNPHNDYCQHFVDTGHRPQNFIRDGGLADRFEEYPKQRELIRLKDELISATNTPPMYLQADPDTFDLRELKCKFDVILIEPPLEEYYRESGIIANERFWNWDDIMKLNIEEISSIRSFVFLWCGSGEGLDLGRMCLRKWGFRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVRRSTDGDFIHANVDIDLIITEEPEMGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNFNIEVYSTHFSEPNSYLSGCTEEIERLRPKSPPPKSMAERGGGAPRGGRGGPAAGRGDRGRERNRPNFRGDRGGFRGRGGPHRGFPPR
What is the function of this protein?
The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis.  In the heterodimer formed with mettl3, mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core.  N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.
What are the official names of this protein?
N6-adenosine-methyltransferase non-catalytic subunit, Methyltransferase-like protein 14.
What is the protein family that this protein belongs to?
Belongs to the MT-A70-like family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CATA1_WHEAT
Sequence: MDPYKYRPSSSFNAPMWSTNSGAPVWNNDNSLTVGSRGPILLEDYHLVEKIADFDRERIPERVVHARGATAKGFFEVTHDVSHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAIKFYTREGNWDLVGNNFPVFFIRDGMKFPDMVHALKPNPKTHIQENWRILDFFSHHPESLHMFTFLFDDIGVPADYRHMDGSGVNTYTLVNRAGKAHYVKFHWKPTCGVKSLLEEEAVTVGGTNHSHATKDLTDSIAAGNYPEWTFYIQTIDPDYEERFDFDPLDVTKTWPEDVVPLQPVGRLVLNRNIDNFFSENEQLAFCPGIIVPGVYYSDDKLLQTRIFSYSDTQRHRLGPNYLLLPANAPKCSHHNNHYDGLMNFMHRDEEVDYFPSRFDPAKHAPRYPIPSRTLNGRREKMVIEKENNFKQPGERYRSMDPARQERFINRWIDALSDPRLTHEIKAIWLSYWSQADKSLGQKLASRLSSKPSM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase-1.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: CLVS2_RAT
Sequence: MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVNEVDKELSPKSMKRSQSVVDPTALKRMDKSEEENMQPLLSLD
What is the function of this protein?
Required for normal morphology of late endosomes and/or lysosomes in neurons.  Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
What are the official names of this protein?
Clavesin-2, Retinaldehyde-binding protein 1-like 2.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle.
Protein: YICR_SALG2
Sequence: MDTLDELLPREKMLRSGIASLSDVELLALFLRTGTPGKDVMTLAKEILQHFGSLYGLLSADFAQFRGVNGIGLAKFAQLKGIAELARRYYSVRMNEESALLSPEMTREFLQSQLTGEEREIFLVIFLDAQHRVLQHSRLFSGTLNHVEVHPREIVREAIKLNASAVILAHNHPSGCAEPSKADKLITERVIKCCQFMDIRVLDHLIIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: RS8_METHJ
Sequence: MARLNTVADAMSTLKNASDTGRAECIVQPAGRLIGELLRIMKEAGYIKEYTRIEDGRGGQFKVVMSGLINKCGCISPRYSVSLDEMEYWEQLYLPSKNIGMLMISTSKGVMGHHDARRNGVGGELLGYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: YOKD_BACSU
Sequence: MKKIVESTTFPRTKQSITEDLKALGLKKGMTVLVHSSLSSIGWVNGGAVAVIQALIDVVTEEGTIVMPSQSVELSDPKEWGNPPVPEEWWDIIRESMPAYNSNYTPTTRGMGQIVELFRSYPEVKRSNHPNYSFVAWGKHKNKILNQHPLEFGLGEQSPLGKLYIRESYVLLLGADFDSSTCFHLAEYRIPYQKIINRGAPIIVEGKRVWKEYKELEFREELFQEVGQAFEAEHNMKVGKVGSANCRLFSLTEAVDFAEKWFINNDSKNIKK
What is the function of this protein?
May contribute to antibiotic resistance.
What are the official names of this protein?
SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD.
What is the protein family that this protein belongs to?
Belongs to the antibiotic N-acetyltransferase family.
Protein: PDXH_ALIF1
Sequence: MELEDIRRDYSLGGLRRADLPQEPVELFELWLKQAVEAKLTDPTAMTVATVDENGQPFQRIVLLKHFDKTGFVFYTNLGSRKAQQLEQHSKISLHFPWHPLERQVHITGTAEKLTALENMKYFTSRPKESQIAAWASKQSSRLTARAALEGKYLELKQKFAKGEIPVPKFWGGFRIKIDSIEFWQGGDHRLHDRFLYSKDQNDWQIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: STRH_STRGR
Sequence: MVMTSPTRKPSGDVRPDEPLHHLDQPFREFLDGLPADRPPWFCFFSSGLLHVLHHFLRFTPERLNCVFICSGLSKEEAELRDRMSGGRPVFDMTEQVGSHEIFELLVRNLDRPFGIVDVDCFVTETDWFERCMDGLEPGVAVSGPLSYGPIPLAAPPFLALDPRVRPDIERAIGGTVTPAAYSYTAPGPEKEIDGAMVRLIEPHHERALARVVALEGPRLPFPQGGLVDVLDDGREVRSHERYHHLQNGNEVIRVVFDGLMFYQLMALAAGLRIAHFHSFPGTKVFAPQLVHAGGISYWHRLRPSEIAAGINELPWAAHVDALLLEEFNRRADVPASYRTRGTRLAANLRRSMVDMAGLRDELRAKLDSSGVDVTDPRWAVVLG
What is the function of this protein?
Is probably a dihydrostreptosyl glycosyltransferase, involved in the first glycosylation step condensing streptidine-6-phosphate and dihydrostreptose.
What are the official names of this protein?
dTDP-dihydrostreptose--streptidine-6-phosphate dihydrostreptosyltransferase.
Protein: EIF3K_ASPFU
Sequence: MGVAFDKCDTRPAHIDAILNGLDRYNPETTTVFQDYVVQQCEERTFDCYANLALLKLYQFNPHLLQPETVTNILAKALTVFPSPAFSLCLALLPAHTQPFPTADTDASQTSDFVESIQKLARLSTLLESAQYAQFWSTLNSDDLYADLVADVAGFEELVRIRIAIEVGKAFREINAEVLEQWLDLRSREALEKFVTEVCSWEVDKTGPNGTVVKVPTNKENEARSEVKSERVGVEMFGRVIRRGFEQAA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M18BP_HUMAN
Sequence: MIATPLKHSRIYLPPEASSQRRNLPMDAIFFDSIPSGTLTPVKDLVKYQNSSLKLNDHKKNQFLKMTTFNNKNIFQSTMLTEATTSNSSLDISAIKPNKDGLKNKANYESPGKIFLRMKEKVLRDKQEQPSRNSSLLEPQKSGNNETFTPNRVEKKKLQHTYLCEEKENNKSFQSDDSSLRASVQGVPLESSNNDIFLPVKQKIQCQQEKKAPLHNLTYELPTLNQEQENFLAVEARNKTLTRAQLAKQIFHSKESIVATTKSKKDTFVLESVDSADEQFQNTNAETLSTNCIPIKNGSLLMVSDSERTTEGTSQQKVKEGNGKTVPGETGLPGSMKDTCKIVLATPRLHITIPRRSKRNISKLSPPRIFQTVTNGLKKNQVVQLQEWMIKSINNNTAICVEGKLIDVTNIYWHSNVIIERIEHNKLRTISGNVYILKGMIDQISMKEAGYPNYLIRKFMFGFPENWKEHIDNFLEQLRAGEKNREKTKQKQKTGRSVRDIRKSMKNDARENQTDTAQRATTTYDFDCDNLELKSNKHSESPGATELNMCHSNCQNKPTLRFPDDQVNNTIQNGGGDDLSNQELIGKKEYKMSSKKLKIGERTNERIIKSQKQETTEELDVSIDILTSREQFFSDEERKYMAINQKKAYILVTPLKSRKVIEQRCMRYNLSAGTIKAVTDFVIPECQKKSPISKSMGTLENTFEGHKSKNKEDCDERDLLTVNRKIKISNLEKEQMLTSDFKKNTRLLPKLKKIENQVAMSFYKHQSSPDLSSEESETEKEIKRKAEVKKTKAGNTKEAVVHLRKSTRNTSNIPVILEPETEESENEFYIKQKKARPSVKETLQKSGVRKEFPITEAVGSDKTNRHPLECLPGLIQDKEWNEKELQKLHCAFASLPKHKPGFWSEVAAAVGSRSPEECQRKYMENPRGKGSQKHVTKKKPANSKGQNGKRGDADQKQTIKITAKVGTLKRKQQMREFLEQLPKDDHDDFFSTTPLQHQRILLPSFQDSEDDDDILPNMDKNPTTPSSVIFPLVKTPQCQHVSPGMLGSINRNDCDKYVFRMQKYHKSNGGIVWGNIKKKLVETDFSTPTPRRKTPFNTDLGENSGIGKLFTNAVESLDEEEKDYYFSNSDSA
What is the function of this protein?
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
What are the official names of this protein?
Mis18-binding protein 1, Kinetochore-associated protein KNL-2 homolog, HsKNL-2, P243.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
Protein: DCD_ERWT9
Sequence: MRLCDRDIEAWLDNGKLGIDPRPPVERINGATVDVRLGNQFRTFRGHTAAFIDLSGPKAEVSAALDRVMSDEIVLPEGDAFFLHPGELALAVTLESVTLPDDLVGWLDGRSSLARLGLMVHVTAHRIDPGWQGRIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNSRQDAKYKGQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: QUEG_FRACF
Sequence: MKLELSLEQWQQVKDFAIRNLNLSSISKADCDLSEYIPYYNKWLENNYHADLEYMVKHGSKRFIPNELVPGTNSVIVATLNYLNRPVNVKTEVKRLRTTSNIADISIYAHGRDYHKVMKKKLQQLGEFIDELTGGHQFRVFTDSAPVLERPLAEKAGLGWQGKSSMLMNKAQGSFFFIGVIYSNLDLSKLPDSPKHQDSCGKCQACIKLCPTGAIQPGKMIDSRKCISYLTIENKGSIPLELRDKIGTRIYGCDDCQLVCPFNNYAPITTEKDFQQRDFLVNKPLLELLAWSEKDFDKYTQGSAIRRIGYAAWIRNIAIAVGNSPFNQDNIQALELKKLEFSDNQLVLEHLDWAINKQKLLS
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase, Queuosine biosynthesis protein QueG.
What is the protein family that this protein belongs to?
Belongs to the QueG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1258_PROMH
Sequence: MPIWVDADACPKVIKEILYRAADREKVVITFVANQRLSIPASPYLRTLQVSAGFDVADNEIVQRANQDDLVITADIPLAAEVIEKGAIALNPRGERYTESTIRERLNIRDFMDTMRASGIQTGGPASLSQRDRQLFANELDKWLLQQKRKK
What are the official names of this protein?
UPF0178 protein PMI1258.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: MUTS2_BACAA
Sequence: MLERTLRVLEYNKVKEQLLEHTASSLGRDKVKHLVPSTDFEEIVEMQDTTDEAAKVIRLKGSAPLGGITDIRSNVKRAKIGSMLSPNELLDIANTMYGSRNMKRFIEDMVDNGVELPILETHVAQIVSLYDLEKKITNCIGDGGEVVDSASDKLRGIRTQIRTAESRIREKLENMTRSSNAQKMLSDSIVTIRNERYVIPVKQEYRGVYGGIVHDQSASGQTLFIEPQVIVELNNALQEARVKEKQEIERILLMLTEEVAVEADIVLSNVEVVANLDFIFAKAFYAKRIKATKPIVNNERYMDLRQARHPLIDPEVIVPNNIMLGKDFTTIVITGPNTGGKTVTLKTVGICVLMAQSGLHIPVMDESEICVFKNIFADIGDEQSIEQSLSTFSSHMVNIVDILEKADFESLVLFDELGAGTDPQEGAALAISILDEVCNRGARVVATTHYPELKAYGYNREQVINASVEFDVNTLSPTHKLLIGVPGRSNAFEISKRLGLSNRVIDQARNHISTDTNKIENMIAKLEESQKNAERDWNEAEALRKQSEKLHRELQRQIIEFNEERDERLLKAQKEGEEKVEAAKKEAEGIIQELRQLRKAQLANVKDHELIEAKSRLEGAAPELVKKQKVNVKNTAPKQQLRAGDEVKVLTFGQKGQLLEKVSDTEWSVQIGILKMKVKESNMEYINTPKQTEKKAVATVKGRDYHVSLELDLRGERFENAMARVEKYLDDAQLASYPRVSIIHGKGTGALRQGVQDYLKKHRGVKTFRYGDMGEGGLGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: HEM3_LISMF
Sequence: MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGLFVSEVEQALSDEVIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNRVNSLDELPQGSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLENTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKLNGGCEIPIAGFATRANEVVHFKGLVGNADGSIILASEQAGANPSEIGNKVAEDLLSEGADTIIKELRNI
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: IPYR_METTH
Sequence: MNLWKDIEPGPSVPEVVYAVVEIPKGSRNKYEYHKDLQAFALDRVLYSAVFYPAEYGIIPRTLYDDGDPMDILVLMDEPTFPGCIIESRPIGLLRMIDGGDQDDKILAVPVADPHFADVKDISDIPEHNLKEIANFFETYKKLEGKKTETLGWEGAEKAFEAVNHSIELYRKKYME
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.