PharMolix/UniProtQA huggingface dataset:
Protein: RIMP_ECO55
Sequence: MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1009_MOOTA
Sequence: MESTLIILAVLVVAVLGRANTVALAASLLLVLKLLQVDQYIFPFIEKGGTFWGLVLLIAAILVPLARGTVTLRDLGHVFLSWVGLSAFILSLITTYMSGQGLQYLTVQGHSEVMPALILGAVIAAAFLGGVPVGPFITSGVLALLVKLIAKL
What are the official names of this protein?
UPF0756 membrane protein Moth_1009.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_CAMJ8
Sequence: MYYCISFTHKNTDIALREKLSFSNEAKKSEFLKIISTHENIEECLVISTCNRVEIVAFVKMACAEFIVKSLALLCDVDKDILLEKADIFEDSGAIHHLFSVASSLDSLVVGETQIAGQLKDAFAFAVKNNFCGVHLSRAVHSAFKCAAKVRNETQISKNPISVASVAVAKAKELADLAQKKAVVIGAGEMGELAAKHLIAAGAKVIILNRDLQKAKDLCERLGVLSEYDSLENLKKYLNQYEFFFSATNAPNAIITNSLIEELPYKRYFFDIAVPRDIDINENENISVFAVDDLENVVQKNLALREQEARMAYGIIGRETSEFFRYLNDLALMPIIKAIRLQAKEYADKQLEIALKKGYLKKSDKEEARKLIHQVFKAFLHTPTVNLKHLQGKMQSDTVINAMRYVFDLQNNLEGLNQYKCEFDMENNDEIY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SECB_ACIAC
Sequence: MSEENPVFQIQRVYLKDLSLEQPNSPQILLEQEQPNVDIQLGVEAAPVADGIFEVAVTATVQTKIKDKTVFLVEAKQAGIFEIRNIPEDQMGPIMGIACPQIVYPYLRGNIADVITRAGFPPVHLAEINFQAMYEQQQSQLASAAPTPGVTQ
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJIG_ECO57
Sequence: MTTQVRKNVMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKITGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMGGAVGVAASLATAGALTGHDVTVLLPAMYLMGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV
What are the official names of this protein?
Inner membrane protein YjiG.
What is the protein family that this protein belongs to?
Belongs to the SpmB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DHB2_HUMAN
Sequence: MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICLAHYLPIGIYDYFAKRHFGQDKPMPRALRMPNYKKKAT
What is the function of this protein?
Catalyzes the NAD-dependent oxidation of the highly active 17beta-hydroxysteroids, such as estradiol (E2), testosterone (T), and dihydrotestosterone (DHT), to their less active forms and thus regulates the biological potency of these steroids.  Oxidizes estradiol to estrone, testosterone to androstenedione, and dihydrotestosterone to 5alpha-androstan-3,17-dione.  Also has 20-alpha-HSD activity.
What are the official names of this protein?
17-beta-hydroxysteroid dehydrogenase type 2, 17-beta-HSD 2, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, Estradiol 17-beta-dehydrogenase 2, Microsomal 17-beta-hydroxysteroid dehydrogenase, Short chain dehydrogenase/reductase family 9C member 2, Testosterone 17-beta-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: AMPA_PSEAE
Sequence: MEFLVKSVRPETLKTATLVLAVGEGRKLGASAKAVDDATGGAISAVLKRGDLAGKVGQTLLLQSLPNLKAERVLLVGAGKERELGDRQYRKLASAVLSTLKGLAGADAALALGDLAVKGRDAHAKARLLVETLADGLYVFDRYKSQKAEPLKLKKLTLLADKADSAAVEQGSKEAQAIANGMALTRDLGNLPPNVCHPTFLGEQAKGLAKEFKGLKVEVLDEKKLRELGMGSFLAVAQGSDQPPRLIVLQYNGAKKDQAPHVLVGKGITFDTGGISLKPGLGMDEMKFDMCGAASVFGTFRAVLELQLPINLVGLLACAENMPSGGATRPGDIVTTMSGQTVEILNTDAEGRLVLCDALTYAERFKPQSVIDIATLTGACIVALGSNTSGLMGNNEALVRQLLKAGEFADDRAWQLPLFDEYQEQLDSPFADIANIGGPKAGTITAGCFLSRFAKKYHWAHLDIAGTAWISGGKDKGATGRPVPLLTQYLLERAK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LALIN_LAVAN
Sequence: MSININMPAAAVLRPFRCSQLHVDETRRSGNYRPSAWDSNYIQSLNSQYKEKKCLTRLEGLIEQVKELKGTKMEAVQQLELIDDSQNLGLSYYFQDKIKHILNLIYNDHKYFYDSEAEGMDLYFTALGFRLFRQHGFKVSQEVFDRFKNENGTYFKHDDTKGLLQLYEASFLVREGEETLEQAREFATKSLQRKLDEDGDGIDANIESWIRHSLEIPLHWRAQRLEARWFLDAYARRPDMNPVIFELAKLNFNIVQATQQEELKALSRWWSSLGLAEKLPFVRDRLVESYFWAIPLFEPHQYGYQRKVATKIITLITSLDDVYDIYGTLDELQLFTNLFERWDNASIGRLPEYLQLFYFAIHNFVSEVAYDILKEKGFTSIVYLQRSWVDLLKGYLKEAKWYNSGYTPSLEEYFDNAFMTIGAPPVLSQAYFTLGSSMEKPIIESMYEYDNILRVSGMLVRLPDDLGTSSFEMERGDVPKSVQLYMKETNATEEEAVEHVRFLNREAWKKMNTAEAAGDSPLVSDVVAVAANLGRAAQFMYFDGDGNQSSLQQWIVSMLFEPYA
What is the function of this protein?
Specifically catalyzes production of (R)-(-)-linalool, the main component of lavender essential oil.
What are the official names of this protein?
R-linalool synthase, LaLINS.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: FOXA_SALTS
Sequence: MPLEMFMFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETPQSVSIITRQQFEEQGATSVRQAVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVALTSRKPAFDAGGEVKLFAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLMAYLHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKVTLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDYITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYSTAFTPTSFADENGNVLEPMKGKQWEAGVKYEPPGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEAISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTLPSYTLVDMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
What is the function of this protein?
Ferrioxamine binding and uptake, in association with the TonB protein (By similarity).  May play a role in intestinal colonization.
What are the official names of this protein?
Ferrioxamine B receptor.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: GAP3_CANAL
Sequence: MTTKEKDEFNIGSLQNSPESSTNMSPDVITTPISKWQAFKDSFKPPEQKPLASSSSSTSSLSASSPHHNDVANNYDIEKSLRPDQQGELKRELKNRHVQMIALGGSVGTGLLIGSGGALHQGGPAALLIAWGITGTMVFCIIHSLGELCVAFPVNGAFSTYANMFVDSSWAFAVGWNYAIMWLIVLPLELVAAAMCITYWNDEINPASWVAIFYVLIVVINIFGVKYYGDAEMYLTIFKIIAIVGFIILGVVLVCGGGPTHEFIGNKYWKQDGAFANGFKGVATTFVTASYSMAGSEMVGLASAEVANPQKSLPKAIRQVFWRIFLFYFLSLTFIGLLVPSNSPQLLGASGTSASPFVIAIKNGGIYALPSIFNACILLSVLSVGNSAVYGCSRTIQSLGAQGLGPKIFAYVDRKGRPLGGLVMSAIFGLLCFLSAYHDEATIFNWLLSVAGLATIFSWFNIGLCHVRFRLALRKQGRSLQELTFTALTGVWGSVYSMIFLCVVLVIQFWTALFPLGSKGKANAENFFQNYLGAVVILIFYVGHKLYTRNWKLCVKLEDIDLDSGRRSFDLDLIRAEIEEEKAANKAKPLYKRLWNYWC
What is the function of this protein?
Amino-acid permease that is able to transport phenylalanine (PubMed:21764911, PubMed:28028545).
What are the official names of this protein?
Amino-acid permease GAP3.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTPPA_CALBD
Sequence: MKRLILASSSPRRIELLKQFGIEFEIIPSNIDESIDQSLSVEENVMQLAKKKAQEVFNKLREENKHFLVIAADTLVFVEGVILGKPSNEDEAFWMLRKISGKWHSVYTGVCIIDGPRERILVEYEKSNVYIKHMSDEEILRYISTKEPFDKAGAYAIQGFGSLIVERIDGCFYNVVGLPLYRLNIMLQKLGYDLMKGEL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_RIPO1
Sequence: MGRTRDNKAAVIADLKELLSDAQLAFVIDYQGLSVSEITELRNRLRPTGSICKVTKNTFMEMAVQEDDNWQPMTQFLTGSSAFVLVKDDVGGAVRAYQGFKKDTKKTEFRGGVMQGQALNEDQVKAIADLPSKEELMAQIAGALNSIATKLAVGINEVPSSVARGINEVPGSLGRVVNAIANKEEGNAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: UBIE_HAEDU
Sequence: MIKDTQSTAENQANETTHFGFKTVAKEEKQQLVANVFHSVAAKYDLMNDLLSFGIHRIWKRFTIDCSGVRKGQKVLDLAGGTGDFSAKFSRIVGETGQVVLADINSSMLEVGRDKLRNLGVVGNINYVQANAEHLPFADNTFDCVVISFGLRNVTDKDKALKSMYRVLKPGGRLLVLEFSKPIFDPISQLYNFYSFNILPKVGGIVVNDAESYRYLAESIRMHPKQDELKTMMEHAGFESVNYYNLSAGIVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: MUG_ECO45
Sequence: MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQAGFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELDQALVVRGR
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLH3_CAEEL
Sequence: MGIGTKILSKIEKNKTSDGLTIPLTPTTQKQSSSWCSFESIKTFFRTVIRDWIFLALLGFIMASLSFGMDYAILNLQNGQMRLFDLVKEYHFTLAYLVWVGYVVGLILLSAVCAHYIAPQAIGSGIPEMKTILRGVILKEYLSVRTLLSKMIGLTLSLGSGLPMGKEGPFVHVASVVASQLTRLVHGSSGGIFENESRSGEMLAAGCAVGVACTFSAPIGGVLFSIEVTSVYFAVRNYWRGFFAATCSATLFRILRMFSVSAAVTVEAHYQTNFPPQNVFLPQELPIFALIGLVCGLAGSIFVYLHRRTVLFLRRNWLAKMIFQKYWLIYPIFIATFISSLSFPLGLGKFMGGEERFSHTMKEFFVDCAWTAPPNDSYACPMPTSNATSSDSFDIRHWKGDNYDYSPFVTLSSFQVVYFFLAILASTLPVPSGIFMPVFVLGAAFGRLVGEGVFSLDPYGHISGDIQFFVRPGVYAVVGAAAFCGAVTHTVSVAVIVFELTGQLCHLLPVMIAVLIANAVASYLQPSIYDSIIRIKNLPYLPDIPHTTSLYHQMLIEQFMISPLVYIAKDSTVGDIKRALETKTRIRAFPLVENMESLALVGSVSRSQLQRYVDSQIGTKARFAEATRRIKQRLEDEESERKRREESKSDDTEDSLETTGAGERRASRFLIVPVAKNGPQVAKNETLTGLSEENARKILTVEEKQALFDAASLATPKREMSGKTINPVHIESHHTIGDIFRSITHLSFGRQNFPKKNNHNEFDLFGEERTEWEDMMLNQKLDLSQLDIDSTPFQLSEYTSLFKAHSLFSLLGLNRAYVTKKGQLIGVVALKELRLAIEYLQSGKVPTPGMSIFNEPPTEQSIYEKSARLESGRATGDAQNAAFVTDNGEDDAQNDYIQPPLEVVRRGALTPNRMSELTRLENVRTTPESPHFEVSSPSTSSSCVSIDFSPLDAANSENGSVGGLVLNVPSLPTRARSANELTRQNTHVQINLPDDVHDEKF
What is the function of this protein?
Voltage-gated chloride channel (PubMed:10567397, PubMed:11078724, PubMed:11231150).  Sensitive to depolarizing conditioning voltages, requires stronger voltages for activation and activation is slower, is inhibited by low concentrations of chloride and is activated by low pH.  Channel gating properties are conferred by the cytoplasmic C-terminus (PubMed:14565992, PubMed:16500974).
What are the official names of this protein?
Chloride channel protein clh-3.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS12_ERYLH
Sequence: MPTINQLVRKGRVPQKAKSKVPAMEQNPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNQREVISYIPGEGHNLQEHSVVLIRGGRVRDLPGVRYHVLRGVLDTQGVKDRKQSRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS2_STRGC
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKYADQAYDFIRDAAANDAIILFVGTKKQAAEAVKDEAERAGQYYINHRWLGGTLTNWSTIQKRVARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEEMPRIPDVMYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPSNDDAIRAVKLITAKMADAIIEGRQGEDSVESVEAELAATETQADSIEEIVEVVEGDNA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL34_PSEA6
Sequence: MKRTFQPSNLKRKRSHGFRARMATKNGRKVIANRRAKGRARLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TKN1_BOVIN
Sequence: MKILVAVAVIFFISTQLSAEEIGANDDFNYWSDWSDSDQIKEEMPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSIEKQVALLKALYGHGQLSHKRHKTDSFVGLMGKRALNSVAYERSVMQDYERRRK
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Protachykinin-1, PPT.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PIGU_RAT
Sequence: MAAPLALVLVVAVTVRAALFRSSLAEFISERVEVVSPLSSWKRVVEGLALLDLGVSPYSGAVFHETPLIIYLFHFLIDYAELVFMITDALTAIALYFAIQDFNKVVFKKQKLLLELDQYAPDVAELIRTPMEMRYIPLKVALFYLLNPYTILSCVAKSTCAINNTLIAFFILTTIKGSVFLSAIFLALATYQSLYPITLFAPGLLYLLQRQYIPVKVKSKAFWIFSWEYAMMYTGSLVVIVCLSFFLLSSWDFIPAVYGFILSVPDLTPNIGLFWYFFAEMFEHFSLFFVCVFQINVFFYTVPLAIKLKEHPIFFMFIQIAIISIFKSYPTVGDVALYMAFFPVWSHLYRFLRNIFVLTCIIIVCSLLFPVLWHLWIYAGSANSNFFYAITLTFNVGQILLISDYFYAFLRREYYLTHGLYLTAKDGTEAMLVLK
What is the function of this protein?
Component of the GPI transamidase complex.  May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
What are the official names of this protein?
Phosphatidylinositol glycan anchor biosynthesis class U protein, Cell division cycle protein 91-like 1, Protein CDC91-like 1, GPI transamidase component PIG-U, Liver regeneration-related protein LRRGT00059.
What is the protein family that this protein belongs to?
Belongs to the PIGU family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SUFS_YERPA
Sequence: MNFPIERVRADFPLLSRQVNGQPLVYLDSAASAQKPQAVIDKELHFYRDGYAAVHRGIHSLSAEATQQMEAVRTQVADFIHAASAEEIIFVRGTTEAINLVANSYGRHFLAAGDSIIITEMEHHANIVPWQMLAQDLGVEIRVWPLTATGELEITALAALIDDTTRLLAVTQVSNVLGTVNPIKDIVAQAKAAGLVVLVDGAQAVMHQPVDVQALGCDFYVFSGHKLYGPSGIGILYGKSALLQQMPPWEGGGAMIKTVSLTQGTTFADAPWRFEAGSPNTAGIMGLGAAIDYVTELGLLPIQQYEQSLMHYALAQLSQIKSLTLYGPTERAGVIAFNLGQHHAYDVGSFLDQYGIAIRTGHHCAMPLMAFYQVPSMCRASLALYNTREDVDRLVAGLQRIEKLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM37_HUMAN
Sequence: MALASGPARRALAGSGQLGLGGFGAPRRGAYEWGVRSTRKSEPPPLDRVYEIPGLEPITFAGKMHFVPWLARPIFPPWDRGYKDPRFYRSPPLHEHPLYKDQACYIFHHRCRLLEGVKQALWLTKTKLIEGLPEKVLSLVDDPRNHIENQDECVLNVISHARLWQTTEEIPKRETYCPVIVDNLIQLCKSQILKHPSLARRICVQNSTFSATWNRESLLLQVRGSGGARLSTKDPLPTIASREEIEATKNHVLETFYPISPIIDLHECNIYDVKNDTGFQEGYPYPYPHTLYLLDKANLRPHRLQPDQLRAKMILFAFGSALAQARLLYGNDAKVLEQPVVVQSVGTDGRVFHFLVFQLNTTDLDCNEGVKNLAWVDSDQLLYQHFWCLPVIKKRVVVEPVGPVGFKPETFRKFLALYLHGAA
What are the official names of this protein?
39S ribosomal protein L37, mitochondrial, L37mt, MRP-L37, 39S ribosomal protein L2, mitochondrial, L2mt, MRP-L2, Mitochondrial large ribosomal subunit protein mL37.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL37 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LEUD_YERPP
Sequence: MAKFIQHIGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFNDWRFLDDAGKVPNPDFVLNLPRYQGATILLARENFGCGSSREHAPWALTDFGFKVVIAPSFADIFYGNAFNNQLLPVTLSEADIDTLFQLVKENEGIEFVVDLEQQTVNAGGKSYAFEIDPFRRHCMINGLDSIGLTLQHEHNISAYEKQQPEFLR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: SULA_ECOLI
Sequence: MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.  The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU) (PubMed:22515815).
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: DAPB_NEIMF
Sequence: MIPLKIAIAGVNGRMGRVLVEAVNNHPDTVLSGALEHSGSEALGLDAGYAVGLKTGIAISDDVDTVLAQSDVLIDFTRPEPTLKHLQKCVEKQVNIIIGTTGFDDAGKAAIQAAGEKTGVVFAANFSVGVNLTFHLLDTVARVLNEGYDIEIIEGHHRHKVDAPSGTALRMGEVIAGALGRDLKQCAVYGREGHTGPRDPSTIGFATVRAGDIVGDHTALFATDGERVEITHKASSRMTFAAGAVRAAVWVNGKTGLYDMQDVLGLNNR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CISY2_MYCTO
Sequence: MTVVPENFVPGLDGVVAFTTEIAEPDKDGGALRYRGVDIEDLVSQRVTFGDVWALLVDGNFGSGLPPAEPFPLPIHSGDVRVDVQAGLAMLAPIWGYAPLLDIDDATARQQLARASVMALSYVAQSARGIYQPAVPQRIIDECSTVTARFMTRWQGEPDPRHIEAIDAYWVSAAEHGMNASTFTARVIASTGADVAAALSGAIGAMSGPLHGGAPARVLPMLDEVERAGDARSVVKGILDRGEKLMGFGHRVYRAEDPRARVLRAAAERLGAPRYEVAVAVEQAALSELRERRPDRAIETNVEFWAAVVLDFARVPANMMPAMFTCGRTAGWCAHILEQKRLGKLVRPSAIYVGPGPRSPESVDGWERVLTTA
What are the official names of this protein?
Putative citrate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: AP1G1_USTMA
Sequence: MSTFFQKQQQVAALDPRLGGLMASAGLYNLKALIKAIRSCKTLADERSLIQKESASIRTAFKDEDPFARHNNIAKLLYIHMLGYPAHFGQIECLKLVATPRFTDKRLGYLGIMLLLDENTEVLTLVTNGLKNDMEHSNMYVCGLALCTFANIASEEMSRDLCNEIEKLMGSSNTYIRRKAAICAMRIVRKVPDLIDHFVDRTQQLLSDKNHGVLLCAVTLAIEICRQDDEALTVYRRAVPLLVQHLKSLVTTGYSPEHDVSGITDPFLQVKILRLLRILGKENAQASETMNDILAQVATNTEASKNVGNSILYETVLTILEIDADNGLRVMAINILGKFLSNRDNNIRYVALNTLSKVVSMDTNAVQRHRNIILDCLRDGDISIRRRALELSYALINESNVRVLTRELLSFLEVADNEFKLGMTTQICLAAEKFAPNKRWHIDTVLRVLKLAGNYVREEILSAFIRLVCHTPELQAYTVQKLFSGLHQDFSQESLTLAAVWVIGEFGDVLIQGGNFEDEELVREVQPKDVVDLLSSVLDSPYVNGLIRQFVLTSLAKLHTRLSDASQQSRIEQIIASFETSVEVEIQQRSVEFATLLKRSDIRQGVLESMPPPEIKQTVLGTVSEAKPVGSTRSDKDALLDLMGDEMPVTSGGGTGADNAPSGATQQSTHDLLADIFGGGDMGGMPSAAPAASASAAQKPKSSVNDILGLFGDGASAPAAAAQQAPTPAPAATSSYGGLDLLGGLGASSSASTPAATPASTVAKSHTVYTKHGLTITLTPTTNPARPEIVHITARFTSATSAISNINFQAAVPKTHKLQMQAISNSTVHPDSTETQPLRVMVPPGAAVRLRLRIAFQVDGHSVQDQTDWAQPSA
What is the function of this protein?
Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  The AP-1 complex interacts directly with clathrin (By similarity).  Required for apical growth extension.
What are the official names of this protein?
AP-1 complex subunit gamma-1, Clathrin assembly protein complex 1 gamma large chain, Clathrin assembly protein large gamma chain, Gamma-adaptin, Gamma-ADA.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.