PharMolix/UniProtQA huggingface dataset:
Protein: EFG_ALKMQ
Sequence: MPREFPLERTRNIGIMAHIDAGKTTTTERILFYSGTTRKLGETHEGASQMDWMDQEKERGITITSAATTCQWLNHRVNIIDTPGHVDFTVEVERSLRVLDGAVAVFCAKGGVEPQSETVWRQGDKYKVPRMAFVNKMDRQGADFFNVMQMMIDRLAANPVAVQLPIGSEEEFTGIIDLVKMEATIYLDDVGQETKIVEIPEELKELAVEYREKLVEAVSETSEELMMKYLEGEALTEEELVKGIRQGTINVQITPVYCGSAYKNKGVQLLLDGVVAYMPSPLDIPAISGIDADTQEEIERHADDSEPFSALAFKIMADPYVGKLAFFRVYSGTLDAGSYVLNSTKGKKERIGRILQMHANTRAEIPTVYAGDIAAAVGLKDTTTGDTLCDPTDAVILESMVFPEPVISVAIEPKTKAGQEKMGVALQKLAEEDPTFKTYTDEETSQTIIAGMGELHLEIIVDRMMREFKVEATVGKPQVAYKETITKAVEVEAKYAKQSGGRGQYGHVKIRMIPQEPGIGYEFTNSTVGGSIPREYVPAVDQGIQGAMVNGILAGYEVVDFKVELYDGSYHDVDSSEMAFKIAGSMAFKEGMRKASPALLEPYMKVEVVTPEDYMGDVIGDLNSRRGQIEGMESRSGAQVIKAFVPLSEMFGYSTDLRSKTQGRATYSMHFNHYAQVPASISEKIMTGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPSF3_DROME
Sequence: MTQATGDARMPDEESDLLQIKPLGAGQEVGRSCIMLEFKGKKIMLDCGIHPGLSGMDALPYVDLIEADEIDLLFISHFHLDHCGALPWFLMKTSFKGRCFMTHATKAIYRWMLSDYIKISNISTEQMLYTEADLEASMEKIETINFHEERDVMGVRFCAYIAGHVLGAAMFMIEIAGIKILYTGDFSRQEDRHLMAAEVPPMKPDVLITESTYGTHIHEKREDRENRFTSLVQKIVQQGGRCLIPVFALGRAQELLLILDEFWSQNPDLHEIPIYYASSLAKKCMAVYQTYINAMNDRIRRQIAVNNPFVFRHISNLKGIDHFEDIGPCVIMASPGMMQSGLSRELFESWCTDPKNGVIIAGYCVEGTLAKAVLSEPEEITTLSGQKLPLNMSVDYISFSAHTDYQQTSEFIRLLKPTHVVLVHGEQNEMSRLKLALQREYEADASTDIKFYNPRNTHAVDLYFRGEKTAKVMGSLAAKNSEVGSKLSGVLVKRDFKYHLLAPSDLGKYTDMSMSVVTQRQSIPWGSSLSTLELLLDRIGAGCVEVLEAERKLRVFGCIELTVEQKIIVMEWQATHVNDVYADAVLACIMQSELGGTNLKGATKQTKSEDSRFRECLIETLQDTFGDNCVPKMFEGDLLPVTVSGKRAEINLETLAISCAEDDVLRQMLNTTVQKLHQTLVSAL
What is the function of this protein?
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.  Has endonuclease activity and functions as mRNA 3'-end-processing endonuclease.  Required for the cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor 73.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DXS_BUCAI
Sequence: MNFNFNKYPILSFANSVENLRLLSVEQLPQLCFELREYLLDVVSISKGHFASGLGVVEITVALHYVYNTPFDNLLWDTGHQAYPHKILTGRGEKINSIRKKNGLHSFPCREESEYDSLSVGHSSTSISAGLGMSIAAEKEGRNRKTICIIGDGAMTAGMAFEAINHAGEIQSNLLVILNDNQMSISRNVGALNKHLKILRSVQNTQKNRKKIRLLNKKLFFKDKRIQNHSISFNSIFSNLGCKYLGPFDGHNIFSIINTLKKIKNKKGTYLLHLVTKKGKGYLPAELNPIKWHTISSRDSSVSKSLSYSDVFGTWLCEIAAFDKKLIAITPAMCEGSGMVKFSRLFPNQYFDVAIAEQHAVTFAAGLAISGYKPVVSIYSTFFQRAYDQLIHDIALQKLSVLFAVDRAGIVGNDGQTHQGVFDLAYLRCIPGIVIMTPSNENECRQMLYTGYMHNKGPSVVRYPKGYGVGELLMPMNRIPIGKSLIKRRGKKIAILNFGILLHNAYCAAEKLDATLVDMRFVKPLDKSMILKLSSQNKFFITLEEGVISGGAGSAVNEFIMVNKIFLPVLNIGLPDTFIPQGTQEEIRHVYKLDSEGIYKQIFYWLRQ
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: SPEB_SALTI
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHHRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLSAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPHHSVQIGIRTEFDKDNGFTVLDACQVNDRGVDDILAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: IXTPA_PORGI
Sequence: MEKLIFATNNPHKLNEIRHILEGKVEIVGLDEIGCREDIPETADTLQGNALLKAEFVHKRYGLPCFADDTGLEVEALDRAPGVHSARYAGEPTNADANVRKLLEALSSVPHPRKACFRTVIALIDDHGKHFFEGKIEGTIASECRGSGGFGYDPVFIPEGHTLSFAEMGEETKNQISHRALAVAQLRDFLLCAK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: RS3_SALPA
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ESPJ_MYCTO
Sequence: MAEPLAVDPTGLSAAAAKLAGLVFPQPPAPIAVSGTDSVVAAINETMPSIESLVSDGLPGVKAALTRTASNMNAAADVYAKTDQSLGTSLSQYAFGSSGEGLAGVASVGGQPSQATQLLSTPVSQVTTQLGETAAELAPRVVAKVPQLVQLAPHAVQMSQNASPIAQTISQTAQQAAQSAQGGSGPMPAQLASAEKPATEQAEPVHEVTNDDQGDQGDVQPAEVVAAARDEGAGASPGQQPGGGVPAQAMDTGAGARPAASPLAAPVDPSTPAPSTTTTL
What is the function of this protein?
Could be involved in regulation of growth and intracellular survival.
What are the official names of this protein?
ESX-1 secretion-associated protein EspJ, TB27.4.
What are the subcellular locations of this protein?
Secreted.
Protein: MURG_SHEB2
Sequence: MTPAGKRILVMAGGTGGHVFPALAVAKYLAQQGWQVRWLGTADRMEARLVPQYGFDIDFIDIKGVRGNGLIRKLAAPFKVVRSILQAKAVIAEFKPDVVLGMGGFASGPGGVAARLAGIPLVLHEQNAIPGMTNKLLSRIATQVLCAFKNTFTTVKAKVVGNPIRQELIALGAEPKPEADEALKVLVVGGSLGAKVFNDLMPEAVAILSQQQSVTVWHQVGKDNLAGVKAAYQQHGQDGGVNIAEFIDDMEAAYRWADVVLCRAGALTVSELAAVGLPSILVPYPHAVDDHQTRNGQVLVEAGAAFLLPQAILDVNKLAGKLQLLANDRTELARMGQRARDVAVLDATEQVAAVCISLAEKG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PETG_OENEH
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: COBQ_METKA
Sequence: MSAIMFVGTASNSGKSFLAAVTCAYLRQRGVDVAPFKSQNMSLNSCVAKENGEIAVAQAFQAAMAGQEPSIHHNPVLLKPKGELRSEVIVHGKPIGTMSYREYREIVFEDPWQAVLESAEILSEEHEVIVAEGAGSPAEINVLDTDIANLRVAEALGADVILVADISRGGAFAAVYGTIELLPERWRRLIKGFLFNKFLGDESLLEPGIKELERRLGVRYLGTVRHVGDFWMPWEDSEALDTHSPGRGSVRIAVIRLPRISNFTDFEPLAMEPDVRVEFVDPRDNLPEDADAVILPGTRTTISDLEELRKRGMDEEVVQAADEGTVVLGVCGGYQMLGRELVDESGGELDPGESVPGLGLLDAVTVFPSDAGKVTVRSEGVVNHPHLRGIRVEGFEIHEGRTYTDEPHLVRLRSGYGNRGCFLDGAYRTDRPVLGTYLHGIFFNRRFRHEFLRWVSGGRWKPPERDVVREAVKRNLQVALEIVESTDLPELLGE
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Probable cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: OXC_ECO57
Sequence: MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAEGIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMISGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPGGVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIILGKGAAYSQADEQLREFIESAQIPFLPMSMAKGILEDTHPLSAAAARSFALANADVVMLVGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELKQNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLVNEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAFGFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDAFRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN
What is the function of this protein?
Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR).  Catalyzes the decarboxylation of oxalyl-CoA to yield carbon dioxide and formyl-CoA (By similarity).
What are the official names of this protein?
Oxalyl-CoA decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: RNP2_PYRFU
Sequence: MSERPKTLPPTLRDKKRYIAFKVISENQFNKDEIKEAIWNACLRTLGELGTAKAKPWLIKFDETTQTGIIRCDRNHVYDVIFSLTLVSDINGNKAIIKVLGVSGTIKRLKRKFLSQFGWR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.  The RNA is catalytic, but its KM for pre-tRNA is 170-fold decreased in the presence of the 4 known protein subunits (Rnp1-4).  The protein subunits also decrease the amount of Mg(2+) needed for activity.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_THEVB
Sequence: MSPPAVDIKVSTDAPPKIVKALNLLGSTGSIGTQTLDIVAQYPDRFRVVGLAAGRNLERLIPQIRQFQPEIVSIADPEQLPELEAALADLPQKPQLVAGEAGIAAVAAYGDAEVVVTGIVGCAGLVPTIAAIKAGKDIALANKETLIAGGPVVLPLLQEYGVKLLPADSEHSAIFQCLQGVPEGGLRKIILTASGGAFRDWPVEKLAQVTVADALKHPNWSMGPKITVDSATLMNKGLEVIEAHYLFGMDYDNIEIVIHPQSIIHSLIELQDTSVLAQLGWPDMRLPLLYALSWPERIPTNWSPLDLVKAGDLTFRSPDHQKYPCMGLAYAAGRAGGAMPAVLNAANEQAVALFIAEAIAFLEIPRLIEMVCDRYSAQNIPNPTLEDILAADRWARATVQELAQRGVSPMVAL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ABD18_MOUSE
Sequence: MGVSKLDILYRRLLLTKLFIRGWGRPEDLKRLFEFRKMIGNRERCQNLVSSDYPVHIDKVEEQSDCKILDGHFVSPMAHYVPGIMPIESVVARFQFIVPKEWNSRYRPVCIHLAGTGDHHYWRRRTLMARPMIKEARMASLLLENPYYGCRKPKDQVRSSLKNVSDLFVMGGALILESAALLHWLEREGYGPLGMTGISMGGHMASLAVSNWPKPMPLIPCLSWSTASGVFTTGVLSKSINWRELEKQYYTQTVYEEEIIHMLEYCGTDSFKMGHEFMNHLPSNADKLTNLNLVSRTLNLDMTDQVVSPKDAKCHKSGKTSISAPSNGQLLQDTAKMECLNQTLSTNKSWFASYNPQSFHLLNREQRRSNRQKESLIFMKGVMDECTHVANFSVPVDPSLIIVVQAKEDAYIPRTGVRSLQEIWPGCEIRYLEGGHISAYLFKQGLFRQAIYDAFERFLHKYAN
What are the official names of this protein?
Protein ABHD18, Alpha/beta hydrolase domain-containing protein 18, Abhydrolase domain-containing protein 18.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RNT2_HUMAN
Sequence: MRPAALRGALLGCLCLALLCLGGADKRLRDNHEWKKLIMVQHWPETVCEKIQNDCRDPPDYWTIHGLWPDKSEGCNRSWPFNLEEIKDLLPEMRAYWPDVIHSFPNRSRFWKHEWEKHGTCAAQVDALNSQKKYFGRSLELYRELDLNSVLLKLGIKPSINYYQVADFKDALARVYGVIPKIQCLPPSQDEEVQTIGQIELCLTKQDQQLQNCTEPGEQPSPKQEVWLANGAAESRGLRVCEDGPVFYPPPKKTKH
What is the function of this protein?
Ribonuclease that plays an essential role in innate immune response by recognizing and degrading RNAs from microbial pathogens that are subsequently sensed by TLR8 (PubMed:31778653).  Cleaves preferentially single-stranded RNA molecules between purine and uridine residues, which critically contributes to the supply of catabolic uridine and the generation of purine-2',3'-cyclophosphate-terminated oligoribonucleotides (PubMed:31778653).  In turn, RNase T2 degradation products promote the RNA-dependent activation of TLR8 (PubMed:31778653).  Also plays a key role in degradation of mitochondrial RNA and processing of non-coding RNA imported from the cytosol into mitochondria (PubMed:28730546, PubMed:30184494).  Participates as well in degradation of mitochondrion-associated cytosolic rRNAs (PubMed:30385512).
What are the official names of this protein?
Ribonuclease T2, Ribonuclease 6.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: FBK65_ARATH
Sequence: MMMSDLSLDLVEEILSRVPATSLKRLRSTCKLWNALFKNPGFTKKQFLKAPKESLVLMLKEYSVCPMIANLSVSAPSIEFKGALNLKNYPPYSEEVDIHEACHCDGLLLCTTMDYRIVVWNPCLGETRWIRWPKNIYSRFALGYEKNKYGRIYKILRCWDRHNSPTGRVDEFEIYEFSSDSWRVLDLVALDCHIASHIGVSFKGNTYWLASDKKDKYGLLLCFDFTTERFTRLCLPPSQDVSKMALSVVGGKQLSLLSQSDSTSKIMEMWVTNIIEDVLMWSKSFTVDIPIRGDYCPYLTSYLVDEEKKVAVCYNENFEKSNKKVYIIGEDNGYYTEIPLVESSYQVWGYPIIFNYVPSLVQIEEGGCIIKE
What are the official names of this protein?
Putative F-box/kelch-repeat protein At3g22730.
Protein: YH028_YEAST
Sequence: MSLSNKCFFFVSKSSSGMRSTSSSPPSMSNLAYWYVAKILSERILRISALLMYTLMEAFLIRNSPSISFNTASGGIEGEKFGREHIIVINIYIYIYIYTSTLQLCV
What are the official names of this protein?
Putative uncharacterized protein YHR028W-A.
Protein: ATG18_BOTFB
Sequence: MNYVTFNQDYSCLAVGTAKGFRIYHTEPFSKIFTGDNENVTIIEMLFSTSLVAIKQSPRHIVIQNTKRGTVICELTFPSAVLAVRLNRKRFAVLLEEEIYLYDIQNMGLLYTISTSANPNAICSLSASSDNCYLAYPLPKPREETGDKRPAHAPPLSPYVAPTSGEVLIFDAKSLKAVNVIEAHRAPLSCIALNNDGTLLATASETGTIIRVFSVPDGQKLYQFRRGTYPSSIFSLSFNMSSTLLCVSSNSDTIHIFRLGGPVTGLPESPQSPGDKDKWRRSRSFDSENGSPPAGISPGSEMADVPAEKSKSSGTFGSMIRRSSQMVGKGVAGVVGGYLPQAVTEMWEPARDFAFIKLPKGGMGVTPRSGPVKSVVAMSSSSPQVMVVTSDGGFYIYSIDMETGGEGVLVKQYSVLESDDSLEPPPINYVSYRT
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct atg9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: FIXB_SHIDS
Sequence: MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQAIQLGANHVWKLNGKPDDRMIEDYASVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: PGK_CHLSY
Sequence: MNKKTIRDVDWAGKRALVRVDFNVPLDDQGQITDDTRIRAALPTIRYLLEHGASVVLMSHLGRPKGKPNPKYSLRPVVERLFELLPEAKEVKKTEAITGPAAEAAVAMLKPGQVLVLENTRFDPREEPNDPAMAAELAKLGDVFVNDAFGTAHRANASTEGVAHYLPAVAGFLMEKELTYIGGALNNPQRPFVTVIGGAKISDKIGVIENLLGKVDALLIGGGMANTFLLAKGLNVGDSLVEPDSVPVAQQLMARAEERGARLLLPVDVVIADAFSADAQRQVVDVSDIPAGWRVLDIGPKTIERYSAEIRAARTVIWNGPMGVFELEPFAVGTRAIAQAMAEAAANGAITIVGGGDSVAAVEQAGLADKMSHVSTGGGASLELLEGRVLPGVAALQDAE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_ECODH
Sequence: MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVRDPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRVRFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGRFYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPED_METCA
Sequence: MDNKLQLHGFNNLTKSLSFNIYDICYAKSEAGQRRYIEYIDEAYSAKRLTQILTDVNAIIGAEILNIARQDYEPQGASVTMLISEGHEAPAAITNSESPGPMPEAVVAHLNKSHITVHTYPESHPHAGISTFRADIDVSTCGRISPLKALNYLIHSFESDIVIMDYRVRGFTRDISGQKHYIDHDITSIQNYISDATADRYQMIDVNVYQEKIFHTKMILKDFNLDNYLFETDKDQLVPEERAHVQKQLQREMAEIFYGRNYKLRR
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: NADD_PSEPG
Sequence: MSKAQAVRRIGILGGTFDPVHIGHLRSALEVAELMGLDELRLLPNARPPHRDTPQVAAQDRLAMVREAVQGVACLSVDARELERDKPSYTIDTLESIRAELAGNDQLFLVLGWDAFCGLPAWHRWEELLQHCHILVLQRPDADVEPPDELRNLLAARSESDPTAMSGPAGNISFVWQTPLAVSATQIRQLLASGKSVRFLVPDAVLAYIEAHELYRAPN
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: VP6_ROTHP
Sequence: MEVLYSLSKTLKNARDKIVEGTLYSNVSDLIQQFNQMIVTMNGNDFQTGGIGNLPIRNWTFDFGLLGTTLLNLDANYVETARTTIEYFIDFIDNVCMDEMARESQRNGVAPQSEALRKLAGIKFKRINFNNSSEYIENWNLQNRRQRTGFVFHKPNIFPYSASFTLNRSQPMHDNLMGTMWLNAGSEIQVAGFDYSCALNAPANIQQFEHIVQLRRALTTATITLLPDAERFSFPRVINSADGATTWFFNPIILRPNNVEVEFLLNGQIINTYQARFGTIIARNFDTIRLSFQLMRPPNMTPAVNALFPQAQPFQHHATVGLTLRIESAVCESVLADANETLLANVTAVRQEYAIPVGPVFPPGMNWTELITNYSPSREDNLQRVFTVASIRSMLIK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: MURC_ORITB
Sequence: MTLLANRRLKSNFGIVHIIGIGGIGMSGIAEIMYNLGYKIRGSDLTSNVNTERLRLLGIEVLHGHNANNINGAGIVVISSAIKHNNPEYQAAILAKIPIISRAEMLAELMRSKVAIAISGSHGKTTTTALIACIFEACGLHPTVITGGIMNNRATNAYLGDGDYFIAEADESDATFIKIPATIAVITNIDVEHLDFYKNFDNLISAFRKFIINLPYDGFAVACIDDITVQNLIAKITSRKIITYGIDSKNAHIQAFNINTDNGYSTYDVRIKAYNFHNEVIITQVTLPALGKHNILNSLAAIAIAVELNLDLNIIKDGFKNFKGIARRFTKIGEYNNITVIDDYAHHPAEIIATIDTARCIADKQQGRVIAVFQPHRYSRLKQLFSEFTHCFQRVDQLYISQIYDAGEQETYNLSHISLVNAIKSYYHSVYVMPINNLDDLPQIIYRQVKPCDIILLMGAGDITKFAAILPQQLQKLLKQHVYSDITTKN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRGB8_RAT
Sequence: MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP
What is the function of this protein?
Orphan receptor.  Probably involved in the function of nociceptive neurons.  May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).
What are the official names of this protein?
Mas-related G-protein coupled receptor member B8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CSRA_CLOB1
Sequence: MLVITRKKGESLLIGDDIEITVVKLDDGSVKLAIDAPKNLTILRKELYNEVQEENKKATNFNPSILKNIKSK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.