PharMolix/UniProtQA huggingface dataset:
Protein: ACASE_CAEBR
Sequence: MDSSSISRWFEYESGHAWCESAYKYQTLPYVAEFANTCTNLPIIVLPLVNIMLLRRYLHDVNGGLVFPQLLLTFNGLASTYYHATLNLFGQLVDELSLVWIITVFLVVYIPVMKWFPERFSKRLTVVRWVVLIVTAVVSALCFLEPNLNAIALMLFSIPAAVVIRYEGKQSGIPDIENFPSRILALWGVAFSFWFADRLLCDFWLYLGTPYLHALFHLLAGLAGYTIFIMFSMIDIESRSKTHRYTAAVRYFPDKNGSIFSFPYISLKERSQ
What is the function of this protein?
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
What are the official names of this protein?
Alkaline ceramidase, AlkCDase, Alkaline N-acylsphingosine amidohydrolase, Alkaline acylsphingosine deacylase.
What is the protein family that this protein belongs to?
Belongs to the alkaline ceramidase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRPA_METPP
Sequence: MSRIAATFERLRGQRRTALIPYITAGDPYADATVDIMLAMAGAGADVIELGVPFSDPMADGPVIQKASERALAKGIGMGQVLAMVRSFREHNDTTPVVLMGYANPVERYGIDRFVADAKSAGVDGVLVVDYPPEECEAFAAQLQGADLDPIFLLAPTSTEQRMKDVGRIARGYVYYVSLKGVTGAGHLDTDAVATMLPRIREHVKVPVGVGFGIRDAATAKALAAVADAVVIGSRIVQLLEAEPRESVAAVGGTFIASIREALDSSTEGVRA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RUVB_PELPD
Sequence: MSRAIAADKREDDSQFDSTLRPKSLDDYIGQEKIKGNLRLFIEAARGRGEALDHVLLYGPPGLGKTTLANIVACEMGVNLKSTSGPVIERPGDLAAILTNLEPHDVLFIDEIHRLSHVVEEILYPAMEDFQLDIIIGQGPSARSIKLDLPRFTLVGATTRAGLLSSPLRDRFGVISRMDFYTHDELATIITRSSRILGMEIEPRGADELSRRSRGTPRIANRLLRRVRDFAQVRADGVITRQVVKETLALLEIDEMGFDHMDRMILLTIIDKFSGGPVGLDTIAAAISEESDTIEDVYEPYMIQNGFLNRTPRGRVATLAAYEHFGRSVPAAPQAALL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GATC_PELPB
Sequence: MSVTTKDVTYIAELAKLKFSDDEMLTMTSELNNILHYVEKLNEVDTEGVLPLSTIHDAVNVLREDVEHQPLSSTAVLLNAPDRQDRFFKVPKVIG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: COAD_BURO0
Sequence: MVVAVYPGTFDPLTRGHEDLVRRASSIFDTLVVGVADSRAKKPFFSLEERLTIANEVLGHYPNVKVMSFTGLLKDFVRVNNARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVEKWLTEKVTAMGGPAA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
Protein: VF307_IIV6
Sequence: MPQTILPISVGQMVLICIFILIILFVITKAKGIKGSWSKKSEIDPFINHSLSFYVPEEDELKDSEGERICRKFLRETVGVLFKDRDGNPEPFNKARPDFLKNPVTSGKNGNFNLEIDCYSPKLKLGVEYNGAQHYKFIPHFHKNKEAFRNQQYRDELKRRMCNDNNVTLIEVPYTVKDIPTYLYNKLKPLGYLNSLQ
What are the official names of this protein?
Uncharacterized protein 307L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 307L family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NCAP_MOKV
Sequence: MESDKIVFKVNNQVVSLKPEVISDQYEYKYPAILDGKKPGITLGKAPDLNTAYKSILSGMKAAKLDPDDVCSYLAAAMHLFEGVCPEDWVSYGIVIAKKGEKINPSVIVDIVRTNVEGNWAQAGGTDVIRDPTMAEHASLVGLLLCLYRLSKIVGQNTANYKTNVADRMEQIFETAPFAKVVEHHTLMTTHKMCANWSTIPNFRFLVGTYDMFFARVEHIYSALRVGTVVTAYEDCSGLVSFTGFIKQINLSPRDALLYFFHKNFEGEIKRMFEPGQETAVPHSYFIHFRALGLSGKSPYSSNAVGHTFNLIHFVGCYMGQIRSLNATVIQTCAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKEMQDYTELEEARVEASLADDGTVDSDEEDFFSGETRSPEAVYSRIMMNNGKLKKVHIRRYIAVSSNHQARPNSFAEFLNKVYADGS
What is the function of this protein?
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: MTNA_ACET2
Sequence: MKPLEYCNGVLKLLDQTLLPGEQKIVELKNYIEVADAIKNMIVRGAPAIGVTAAYGVAIASKAINTDSKEEFFAELAKVCDIIKSTRPTAVNLFWAVDRVYSRAVSNRDKTIEEIKKLIEEEAYLMEKEDIESNRSIGRFGNELIKENWTILTHCNAGALATCDYGTALGVIRAAHESGKNIQVFADETRPYLQGARLTAWELMQDNIPVTLICDNMAGHFMKEGLIDCVIVGADRIALNGDTANKIGTYSLAVLAKENNIPFYVAAPTTTIDFSIETGEQIPIEERSPAEITHIKGIRIAPEGVKVRNPAFDVTPNKYISAIITEKGIIYPPYDENIKKYR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: CYHEI_AFREN
Sequence: GSTPCGESCVWIPCISGIVGCSCSNKVCYMD
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide hyen-I.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: FEN1B_XENLA
Sequence: MGIHGLAKLIADVAPAAIKEHDIKSYFGRKVAVDASMCIYQFLIAVRQDGNMLQNEEGETTSHLMGMFYRTIRMLEHGIKPVYVFDGKPPQMKSGELAKRSERRAEAEKLLEAAEEAGEVENIEKFNKRLVKVTKQHNEECKKLLSLMGIPYVDAPCEAEATCAALVKAGKVYAAATEDMDALTFGTPVLLRHLTASEAKKLPIQEFHLNRVFQDIGINHEQFVDLCILLGSDYCETIRGIGPKRAIDLIRQHKTIEEIIDNIDLKKYPIPENWLHKEARQLFLEPEVIDADITELKWTEPDEEGLVAFMCGEKQFSEDRIRNGAKKLAKNRQGSTQGRLDDFFKVTGSISSTKRKEVESKGSTKKKSKTGGTPAGKFKRGK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1-B, FEN-1-B, Flap structure-specific endonuclease 1-B, xFEN-1b.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: RL7_LEVBA
Sequence: MAFDKDTIIASLKEASITDLSDLVKAIEDEFGVSAAAPVAAAGAAGGDAAGAKDSFDVEMTESGDAKVKAIKAVREITGLGLKDAKGLVDNVPSVIKEGVSEDEANDIKEKLEAVGAVVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PA1_DINQU
Sequence: MKFITAILVIFCVYLLSTAGDSKILPLKKLPSKIFGHLKSHVDNTVKKPLKVFGHLKSHVENSVGPLRMNKLTPNCIFGVKSMSMVLFTKNIPDGKYISLDSDLGRDLDLTKTIYFTAHGFISNVNHSLSNRLSRALVEKDYTVFSLDWSDAACTTGGLPLVKLLGYPSAVQNTREIGNLMADYVMSLIDHGASLRNMAFIGHSLGSHVCGFASKKIYESGYGKVPLLFAADPAQPLFQLKQCPDRLCDTDAKLVITLHTSQIGLGYPIGGLDLYFNGGFVQPKCHLDITCAHIRSVLYLINMVEKKCSFPGIPATYKQILNPFSKFPYPNSKTTDCFVMDDSIFNPRRKSLQNLAGGIYYMFVDPDTFCTRKNFNCQR
What is the function of this protein?
Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity).  May act as an allergen and induce hemolytic activity (By similarity).
What are the official names of this protein?
Phospholipase A1, PLA1, Venom allergen 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSAD_RHOP5
Sequence: MASDAASLVLGIETTCDETAAAVIERRADGSGQILSNIVHSQIEDHAPFGGVVPEIAARAHVDLLDGIIARAMREADVGFAQLSGVAAAAGPGLIGGVIVGLTTAKAIALVHETPLIAVNHLEAHALTPRLTHALEFPYCLFLASGGHTQIVAVLGVGDYVRLGTTVDDAMGEAFDKVAKMLGLPYPGGPQVERAAETGDADRFAFPRPMLGRAEPNFSLSGLKTAVRNEASRLMPLERQDIADLCAGFQAAVLDATADRLKVGLALFRDRFGPPHALVAAGGVAANQAIRRALHDVAVAAGTVLMMPPPKLCTDNGAMIAWAGAERLALGLTDPLDTAPRARWLLDANIATPAKFANTRAGF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU1_NITEC
Sequence: MAKSKFERVKPHINVGTIGHVDHGKTTLTAAITTILTRKFGGEAKSYAQIDSAPEERARGITINTSHVEYETDKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIIVFMNKADMVDDAELLELVEMEIRELLSKYDFPGDDTPIIIGSALKALEGDKGDIGEAAILKLAEVLDSYIPEPQRAIDGAFIMPVEDVFSISGRGTVVTGRVERGIVKVGDEIEIVGLRPTIKTTCTGVEMFRKLLDQGQAGDNVGILLRGTKREEVERGQVLAKPGSILPHTKFSAEIYVLSKEEGGRHTPFFAGYRPQFYFRTTDVTGSIELPAGVEMVMPGDNISVNVNLIAPIAMSEGLRFAIREGGRTVGAGVVAKVIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBG5_ARATH
Sequence: MAFLSKVGRLFSQTSSHVTASSSMLQSIRCMSSSKIFVGGISYSTDEFGLREAFSKYGEVVDAKIIVDRETGRSRGFAFVTFTSTEEASNAMQLDGQDLHGRRIRVNYATERGSGFGGRGFGGPGGGYGASDGGYGAPAGGYGGGAGGYGGNSSYSGNAGGGGGYGGNSSYGGNAGGYGGNPPYSGNAVGGGGGYGSNFGGGGGYGVAGGVGGSENFAQGSSTNAGFDDKFESNQPLGNDTDHQTESGLGGDEQFGGSDNQFGDAENGNTENGPVGFDQTDDGDVAKRA
What is the function of this protein?
Possibly has a role in RNA transcription or processing during stress (By similarity).  Binds RNAs and DNAs sequence with a preference to single-stranded nucleic acids.  Displays strong affinity to poly(U) sequence (PubMed:11972043).  Involved in C-to-U editing of mitochondrial RNA.  Functions as major mitochondrial editing factor.  Controls 44 percent of the mitochondrial editing sites (PubMed:26578708).
What are the official names of this protein?
Glycine-rich RNA-binding protein 5, mitochondrial, AtGR-RBP5, AtRBG5, Mitochondrial RNA-binding protein 2b, At-mRBP2b, Organelle RRM domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the GR-RBP family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL17_NITOC
Sequence: MRHRYSGRRLNRTSAHRKAMFRNMAVSLIEHEMINTTLPKAKEFRRVAEPLITLAKEDSVANRRLVFSRLRDRKAVTKLFNELGPRYQARPGGYLRILKRGFRAGDNAPMAIVELLERPLPDSQEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: I17RB_HUMAN
Sequence: MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
What is the function of this protein?
Receptor for the pro-inflammatory cytokines IL17B and IL17E.  May play a role in controlling the growth and/or differentiation of hematopoietic cells.
What are the official names of this protein?
Interleukin-17 receptor B, IL-17 receptor B, IL-17RB, Cytokine receptor-like 4, IL-17 receptor homolog 1, IL-17Rh1, IL17Rh1, Interleukin-17B receptor, IL-17B receptor.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: MOAG4_CAEEL
Sequence: MTRGNQRDLAREKNQKKLADQKKRQGASGQDGNAGLSMDARMNRDADVMRIKQEKAAAKKEAEAAAAAANAKKVAKVDPLKM
What is the function of this protein?
Positive regulator of protein aggregation and age-related proteotoxicity (PubMed:20723760, PubMed:28336532).  Induces conformational changes in aggregation-prone proteins, driving them into compact formations preceding the formation of aggregates (PubMed:20723760, PubMed:28336532).
What are the official names of this protein?
Modifier of protein aggregation 4, Small EDRK-rich factor, SERF.
What is the protein family that this protein belongs to?
Belongs to the SERF family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: FDHE_ACTSZ
Sequence: MAIRILPENEIKQVASSFQNPPLLFSSPQNLYARRAQRLRQLAENHPFSDYLLFAADVVEAQNLIFAENPLEKTEFTFNQLRPLDIKHWPRSAKWREYLSALLAEIKPRANEQMIGTIDCLEKASSEELERLADKLLVQEYAQVASDKAVFIWAALSLYWVQLTQFIPHHAIMENAEDLHTCPVCNSVPVASVVQFGSNQGLRYLHCSLCESEWNVVRAKCTVCDQSKELEYWGIDTDKETVKAETCGDCHSYLKTVYQEKDPYVDPVADDLASIFLDIEMEEKQFSRSGLNPFVFPAE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_BACFR
Sequence: MFNSFGNIFRLTSFGESHGKGIGGVIDGFPAGIVIDEEFVQQELNRRRPGQSVITTSRKEADKVEFLSGIFEGKSTGCPIGFIVWNENQHSNDYNNLEKVYRPSHADYTYTVKYGIRDHRGGGRSSARETISRVVGGALAKLALRQLGIHITAYTSQVGPIKLEGNYTDYDLDLIETNPVRCPDPEKAKEMQDLIYKIKGEGDTIGGVLTCVIKGCPIGLGQPVYGKLHAALGNAMLSINAAKAFEYGDGFKGLKQKGSEQNDVFYNNNGRIETRTNHSGGIQGGISNGQDIFFRVAFKPVATVLMEQETVNIDGIDTTLKARGRHDPCVLPRAVPIVEAMAAMTILDYYLLDRMTQL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: Y1183_CITK8
Sequence: MFCVIYRSSKRDQTYLYVEKKDDFSRVPEDLMKGFGQPTLAMILPLDGRKKLVNADLEKVKQALTDQGYYLQLPPPPEDLLKQHLSAPGENKPDAKS
What are the official names of this protein?
YcgL domain-containing protein CKO_01183.
Protein: COPG2_RAT
Sequence: MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTMEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLLKESEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISLCQKYPRKHSVMMTFLSNMLRDDGGFEYKKAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQNESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMALNATYIFNGLTVSIPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKSEITLVTPKPEKLAPSRQDIFQEQLAAIPEFVNLGPLFKSSEPVQLTEAETEYFVRCVKHMFTDHIVFQFDCTNTLNDQLLEKVTVQMEPSDSYEVLCCVPAPSLPYNQPGICYTLVRLPDEDPTA
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit gamma-2, Gamma-2-coat protein, Gamma-2-COP.
What is the protein family that this protein belongs to?
Belongs to the COPG family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (By similarity). Over 60% of the COPG1-containing coatomers are found in the trans-Golgi apparatus and less than 40% in the cis-Golgi.
Protein: DUT_AERHH
Sequence: MTTQIELKILDARIGTEYPLPAYATPGSAGMDLRALLDAPLTLAPGDTTLVPTGLAIHIQDPGLCATILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSVWNRGNDNFTMQPGERIAQLVIMPVVQASFQLVDEFNQSERGEGGFGSSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PLCB4_BOVIN
Sequence: PVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKQGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKKQTTETEVEKKQLEALKSMMEAGESAAPVNMLEDDNEEEIESAEQEEEAHPEYKYGNELSADDLGHKEAIANSVKKASDDLEHENSKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNSGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAALGAGLEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELSSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKLTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSDMINTHSAEEQEIRDLLLSQQCELLRKLLISAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFVEKQNEQAKEMQQMVKLEAEMDRRPATVV
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.  This form has a role in retina signal transduction.
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4, PCL-C1, Phosphoinositide phospholipase C-beta-4, Phospholipase C-beta-4, PLC-beta-4.
Protein: TSAD_BURVG
Sequence: MLVLGIESSCDETGLALYDTQRGLLAHALHSQIAMHREYGGVVPELASRDHIRRALPLLDEVMIQSGTHRDDIDAIAFTQGPGLAGALLVGASIANALALAWNKPTIGIHHLEGHLLSPLLVDAPPPFPFIALLVSGGHTQLMRVTDVGVYETLGETLDDAAGEAFDKTAKLIGLGYPGGPEVSRLAETGTPGAVVLPRPMLHSGDLDFSFSGLKTAVLTQMKKFEAAKLEGDALERAKADLARGFVDAAVDVLVAKSLAALKQTKLKRLVVAGGVGANRQLRAALSAAAAKRGFDVHYPDLALCTDNGAMIALAGALRLGRWPEQANTDYAFTVKPRWDLASLAR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGA15_CANAL
Sequence: MKFIIILFTLISIVTAAQRIYNKDYSYYGCNSYCDKASDQEDACGYYDDDVSYQDYYGCLCGNEIFLSNLKSCDCFTSIIASVSKSVCSKATEDSDWGYYDDSTSSIMDFFTADNTPASNTGMTTQTDGAINDNQNTGSKTSSGAANYLTSFSIGTFFVFVLGLI
What is the function of this protein?
Probable GPI-anchored cell wall protein that may be involved in cell wall organization, hyphal growth, as well as in virulence.
What are the official names of this protein?
Probable cell wall protein PGA15, Predicted GPI-anchored protein 15.
What is the protein family that this protein belongs to?
Belongs to the IHD1 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.