PharMolix/UniProtQA huggingface dataset:
Protein: LEG8_HUMAN
Sequence: MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
What is the function of this protein?
Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy (PubMed:22246324, PubMed:28077878).  Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture (PubMed:22246324, PubMed:28077878).  Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52 (PubMed:22246324, PubMed:28077878).  Required to restrict infection of bacterial invasion such as S. typhimurium (PubMed:22246324).  Also required to restrict infection of Picornaviridae viruses (PubMed:28077878).  Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans (PubMed:21288902).
What are the official names of this protein?
Galectin-8, Gal-8, Po66 carbohydrate-binding protein, Po66-CBP, Prostate carcinoma tumor antigen 1, PCTA-1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Cytoplasm, cytosol.
Protein: METN2_BACC1
Sequence: MISFNNVSKVYETGGQSVHAVEDVTLSVEKGEIFGIIGFSGAGKSTLLRLVNMLERPTAGTISIDDKEITSLSTKELRKLRQRIGMIFQSFNLFNSRTVFGNIAYPLKLAKVPKNEIKERVNELLKFVGLEDKANNYPEQLSGGQKQRVGIARALATSPDILICDEATSALDPETTTEILNLLKKVNREYNLTILLITHEMHVVKEICHRVAVMEKGKVIEEGKLFDVFTQPKTKTTQNFVRSVINDHLPESVLAKIQNGGQIYRLTFTGEETGQPVLSYIAKNYNVDVNVLYGNIIELQNVLFGNLLVELQGEQREIQKALQHLRLQVQLKEVEAHAS
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CARB_BACCN
Sequence: MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTATADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLEECGVEILGTKLSAIEQAEDRDLFRTLMQELNEPTPPSEIVHTLDEAYEFVKEIGYPVIVRPAFTLGGTGGGICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGFKEIEYEVMRDANDNAIVVCNMENIDPVGVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRWPFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELNHLKELDKETMKKRIIKADDERLFIVAEAIRQGVTKEEIHEWCEMDFFFLQKIENIVNMERKVKANVGDMEVLREAKEMGFSDHYIASAWNKTECEIYATRKENGIMPVFKMVDTCAAEFESATPYYYSTYGDENESIVTERKSVMVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIIVNNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLAERGVKILGTSLEDLDRAEDRDKFEAALTELGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYVLGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVYIPGIMEHIERAGVHSGDSIGVYPPQSLSAKVKEQIIENTIALGRGLKIVGLLNIQFVVFKDEVYVIEVNPRASRTVPFLSKITGVPMANIATKVILGKNLVEQGYETGYHPEDNEVYVKAPVFSFAKLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVAAGISIPTHGSVIITVADKDKEEAIEIARRFHEIGYNLLATAGTAKSLTEQNIPVQVVNKIDSEDYNLLDIIRQGKAQFVINTLTKGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHTMKEIAPTTRHEVVHA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: GCSH3_SACS2
Sequence: MKILGFTFPDDLLYEPEKHVWVRIEDNSVVSIGVTDLGQYMAGKIFQVTAKQKGEKVNGRSVLFSIESAKWIGKFRLPIEGEVFDVNEEVVKNPSIINERPYDSWIVKIRVEDMDIIKRTFKPIQEVYKQFEEEAKRVVR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Probable glycine cleavage system H protein 3.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: LIPA_ZYMMO
Sequence: MSKIPAPDEKTSRSDSGSSILRKPDWLRVRSPGGAAFNETHGLIRKLGLATVCEEAACPNIGECWTKKQATVMILGEVCTRACAFCNVKTGHPDKVNPLEPGHVADVAAEMNLEHIVITSVDRDDLEDGGASQFVKVIEAVRARTPKTTIEILTPDFRGKPDHALDMIVKARPDVFNHNLETVPRLYPTIRPGARYFTSLRLLEKVRERDPSIFTKSGLMLGLGEDRLEVHQVMDDMRQADVDFLTLGQYLQPTPRHVRVEEFVTPDSFKAYAATARAKGFSMVASSPLTRSSYYAGADFARLKEARQKKLEKIAAKNSGKGA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_THEP3
Sequence: MAIQIVLIVGPTASGKSKLAVDVAKEFNGEIISADSMQVYKYMDVGTAKITKEEMQGIPHYLIDIVEPDQEFSVAEYEKRAKEIIKDIYKRGKLPIIVGGTGLYINSIIYIMHFSDFEGSKEFREKMKELANTYGSQYLYEKLKSVDPEAAKKIHPNDIRRIIRALEVYEFTGKPISYYQKMSGMRLNPEYQPIMIGLNFRDRQILYDRINQRVDEMIKNNLVEEVVNLLKIGYNKDSTAMQALGYKEIVEYLKGEISLEEAIEKIKKGTRRYAKRQITWFKGYDFIKWFFVDDYKNYEELKKNIIKYLAGKLNF
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ARLY_AZOVD
Sequence: MSAEKTNQSWGGRFSEPVDAFVARFTASVDFDKRLYRHDIMGSIAHASMLEQAGVLSAAERDAIIDGLKQIQSEIEAGQFDWRVDLEDVHMNIEARLTERIGITGKKLHTGRSRNDQVATDIRLWLRDEIDTILGEITRLQQGLLEQAERHAEVIMPGFTHLQTAQPVTFGHHLLAWFEMLARDHERLVDCRKRVNRMPLGSAALAGTTYPIQREITCRLLGFEAVGGNSLDGVSDRDFAIEFCAAASLAMMHLSRFSEELVLWTSAQFNFIELPDRFCTGSSIMPQKKNPDVPELVRGKSGRVFGHLTGLLTLMKGQPLAYNKDNQEDKEPLFDAVDTLRDSLRAFADMVPAIKPRVEAMREAARRGFSTATDLADYLVRKGLPFRDCHEIVGHAVKYGVESGKDLAEMSLDELRRFSDQISEDVFAVLTLEGSVNARDHVGGTAPAQVRAAVARGRALLAAR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_CHLAA
Sequence: MPRLSEAEIAEQLAQRPDWSLENNEIVRTFRLANFPAAIAFVTHVAFLAEAAGHHPDIDIRYNRVRLALTTHDAGGLTEKDFALAAAIDEIMG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: F16PA_TERTT
Sequence: MEITKTLGEFIVDHQNQYPTATGELSALFSSIRLAGKIVHREVNKAGLADIRGAAGGDNIQGEAQQKLDVYANEKFKAALSARGVVCGLASEEEDSFVAFDGQRSLQGKYVVLIDPLDGSSNIDVNVSVGTIFSIYRRISKTGGPVTLEDFLQPGRAQVAAGYIVYGSSTMLVYSTGDGVNGFTYDPSLGVFCLSHENMRCPPEGNIYSVNEGNYVHFPSGIKKYIKFCQEEDKPSGRPYTSRYIGSLVSDFHRNLIKGGIYLYPTSSTYPSGKLRLLYECNPMAFLAEQAGGKALAGVNQPVLDIVPSELHQRSPLIIGSSRMVDKACEFLSEK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGS_SELML
Sequence: MSLVCFPFKEEDVAVVVRNVECAAAHPRVSTVLCVGYSKGETWCAIEAKRPSIESSTGKRIILLQQKRIGVSLRSGKGDGMNTALAYFLDHTELKRIHFYDSDIVSFSADWITKAERQADLDFDVVRHYFPRSSTDAMITWFVTKIGFCLLWPKTVLPFIEQPLGGELLLTRKAAEALYTDHRVRGQSDWGIDTLYTFIMVQKGLHLAEVYIPEGKVHALYSGLRDLRTMLVECFSAMQSLKDEAVPLNEGTHRMEYTRPVPELVKQKVGYDVEKTLKLLRSNWTQGQRDLLQKHFDPALAKGLLNASEWPTWGFADEEAWVAAYRTLLVHFEKGDEDWEELLFKIWVSRVLNHTMRHSLRGYDAALDALRSLIWETQHQSAMLSKSAAANHHIVSGHSASEALPRTAGQLREKRMDAACAV
What is the function of this protein?
Involved in the biosynthesis of the compatible solute alpha-D-mannosyl-glycerate (MG) (PubMed:23179444).  Catalyzes the condensation of GDP-alpha-D-mannose (GDP-Man) with D-glycerate to produce alpha-D-mannosyl-glycerate (PubMed:23179444).  Can also use GDP-alpha-D-glucose (GDP-Glc) as sugar donor to produce alpha-D-glucopyranosyl-glycerate (GG) (PubMed:23179444).
What are the official names of this protein?
Mannosylglycerate synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 78 family.
Protein: DPOG2_DROME
Sequence: MSRIQRCFKSLASAGFFRTVEDNKLELLSHGREYAKLLQQHWTRLRPLAAHLGATKEPINPVNIQRFSFPQSQQFRNNFQKLVKDHPRKAKCPTLLKHQSTCSGPTSNSLFGIKGPTLHLTTDFLVEPHRALEHFYNMQRESKIWWMRLSSNPSRYRIVPCDLAEDLNPNDYQAIDIRTSYGDAGEVTVEQLSLVRIVDDKDFRLPDARTGEIVQPTVIRSVIELETTTCALLLDGCDHGRDSQSLLLHRVLAPYQCGIACVESDSELSADLSDLCQHLKHVLNHAGLRLSEGDGIRTTKNASHLAEHLLETDMLGIPYTLVINEQTLRNGLMQLRSRDTRLAETIHISDVPDYLLNIFKN
What is the function of this protein?
As accessory component of the DNA polymerase gamma complex is involved in the replication of mitochondrial DNA (PubMed:3095323, PubMed:7499423).  Does not bind DNA (PubMed:7499423).  Essential for mitochondrial DNA maintenance and larval development (PubMed:11917141, PubMed:19924234).
What are the official names of this protein?
DNA polymerase subunit gamma-2, mitochondrial, DNA polymerase beta subunit, DNA polymerase gamma 35kD subunit, DNA polymerase gamma subunit 2.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TATA_POLAQ
Sequence: MGSFSIWHWLIVLVIVMLVFGTKKLRNIGQDLGGAVKGFKDGMKSAEDPNEQIPQSTTTAEKTVDVQAKDINK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL36_VIBA3
Sequence: MKVRASVKKICRNCKVIKRNGVVRVICSEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: Y1022_LACP3
Sequence: MSGHSKWHNIQGRKNAQDSKRGKIFQKLSRELYMAAKQGGPDPSGNPSLRLVMDKAKAANMPKDNIKRALDKASDRDAANYDEVTYEGYGPGGVAILVEALTDNRNRTSSTVRVAITRHGGNMAAAGAVSYMFDRKGYLVISRDDLDVDEDQMLEDALEAGAEDMQTSDEAFEIYTDPKEFAQVRDALEEKGYKFVQNELTMVPQNLTPIPEDKVEKFQAMIDQLEDDDDVQEVYTAGDWPDD
What are the official names of this protein?
Probable transcriptional regulatory protein LSEI_1022.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_METCA
Sequence: MFSKGMEIAGFDDELWAAIQEEERRQEDHIELIASENYASPRVLQAQGTVLTNKYAEGYPGKRYYGGCEYVDIVETLAIERAKRLFGADYANVQPHSGSQANAAVYMALLKPGDTVLGMSLAHGGHLTHGAKVNFSGKIYNAVQYGLNPETGEIDYDQVDELAREHRPKMIVAGFSAYSQVVDWQRFRAIADSVGAWLMVDMAHVAGLIAAGLYPSPVQIADVTTTTTHKTLRGPRGGLILAKANPEVEKQLNSLVFPGIQGGPLMHVIAAKAVALKEALQPDFRHYQSAVMENADAMAKTFIERGYRIVSGGTRNHLFLVDLIQKGLTGKLAEEVLGRAHITVNKNAVPNDPQSPFVTSGIRVGTPAVTTRGFGVEECRLLAGWMCDIMDCPGDETVIGQVREEVTHLCRRFPVYAN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETR1_PELHO
Sequence: MEACNCFEPQWPADDLLMKYQYISDFFIAVAYFSIPLELIYFVKKSAVFPYKWVLVQFGAFIVLCGATHLINLWTFNLHTRTVEIVMTTAKLMTAAVSCVTALMLVHIIPDLLSVKTRELFLKNKAAELDREMGLIRTQEETGRHVRMLTHEIRSTLDRHTILKTTLVELGRTLGLEECALWMPTRTGLELQLSHTLRQQNPVGYTVPIHLPVLNQVFSSNRAIKISPNSPIARLRPLAGKYVPGEVVAVRVPLLHLSNFQINDWPELSTKRYAMMVLMLPSDSARQWHVHELELVEVVADQVAVALSHAAILEESMRARDLLMEQNVALDMARREAETAIRARNDFLAVMNHEMRTPMHAIIALSSLLQETDLTSEQRLMVETILKSSNLLATLINDVLDLSRLEDGSLQLDIATFNLHAVFRQVFNLIKPIASVKKLFITLNVSPDLPEYVIGDEKRLVQIMLNVVGNAVKFSKEGIISVTAFVAKSESVRDPRAPDFFPVSSDNQFYMRVQVKDSGSGINPQDMPKLFTKFAQSQPVATKNSGGSGLGLAISKRFVNLMDGHIWIDSEGPSKGCTVTFVVKLGIPEGSNEPKLPLMPKVSANNSQTDFPGLKVLLMDENGISRMVTKGLLMHLGCDVTSVSSSEECLRMVSQDHKVVFMDVRVPGLDGHELAVRIHEKFMKRHERPLIVALTSNADKVTKENCLRVGMEGVILKPVSVDKMRNVLSKLLEHRILFEA
What is the function of this protein?
May act early in the ethylene signal transduction pathway, possibly as an ethylene receptor, or as a regulator of the pathway.
What are the official names of this protein?
Ethylene receptor 1, PhETR1.
What is the protein family that this protein belongs to?
Belongs to the ethylene receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS16_TRIL1
Sequence: MATKIRLQRHGAKKRPFYQVVIADERSRRDGRFIENVGYYDPTKNPAVLKLNVEKVIAWLDKGAQPTDTVNQILKKEGILEKAAQAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: DBP3_LODEL
Sequence: MGSSSKSEKRKYDDGEELLERKKLKLQKKQEKKEKKDKKEKKDKKEKKDKKEKKDKKEKNKESKEAEARDDSGSNVQASSSSSTESTSYGYVQSSKVKDVPQSEVDKFLTDNEVTVEDPQHLHYRPILSFDQIKLQKDVSSKLTKFPKPTPIQSVSWPFLLDGKDVVGVAETGSGKTFAFGVPAINNIITSKNKDLSVLCISPTRELALQIYDNLEDLTRGTDVSCVAIYGGVSKDDQIKKIRNGANVVVATPGRLVDLINDGAVDLSSINYLVLDEADRMLEKGFEEDIKLIIGSTPAQGRQTLMFTATWPKEVRELANNFMNQPVKVTIGDRDELSANKRITQIVEVLDDKFQKEKKLINLLQKYQNTGNGDNKILVFALYKKEASRIESLLHRNKFKVAAIHGDLSQQQRTQALQSFKSGECNLLLATDVAARGLDIPNVKYVINLTFPLTIEDYVHRLGRTGRAGQTGIAHTFFTEDEKHLSGALCNILRGANQPVPEALLKYGGHTKKKTHSVYGAFYKDVDMPIDSKED
What is the function of this protein?
ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis.  Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TCMPB_STRMU
Sequence: MAIFNHLPSSVLQCLAIFLSIIIEALPFILLGAILSGFIEVYLTPDIVQKYLPKNKIGRILFGTFVGFIFPSCECGIVPIVNRFLEKKVPSYTAIPFLATAPIINPIVLFATFSAFGNSWRFVFLRLFGAIIVAISLGILLGFIVDEHIIKESAKPCHFHDYSHKKAYQKIFYALAHAVDELFDTGRYLIFGSFVAASMQIYVPTRILTSIGHNPLTAILIMMLLAFILSLCSEADAFIGTSLLATFGVAPVVAFLLIGPMVDIKNLMMMKNAFKTKFILQFVGTSSLIIIIYCLIVGVMQ
What is the function of this protein?
Could be part of a two-component membrane permease system responsible for amino acid transport under low pH.  Involved in acidogenesis, biofilm formation and low-pH survival.
What are the official names of this protein?
Putative two-component membrane permease complex subunit SMU_747c.
What is the protein family that this protein belongs to?
Belongs to the UPF0718 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: END4_THEMA
Sequence: MIKIGAHMPISKGFDRVPQDTVNIGGNSFQIFPHNARSWSAKLPSDEAATKFKREMKKHGIDWENAFCHSGYLINLASPKDDIWQKSVELLKKEVEICRKLGIRYLNIHPGSHLGTGEEEGIDRIVRGLNEVLNNTEGVVILLENVSQKGGNIGYKLEQLKKIRDLVDQRDRVAITYDTCHGFDSGYDITKKEGVEALLNEIESLFGLERLKMIHLNDSKYPLGAAKDRHERIGSGFIGEEGFAVFFSFKEIQEVPWILETPGGNEEHAEDIKKVFEIIEKFGIEVD
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: DCDA1_ARATH
Sequence: MAAATQFLSQPSSLNPHQLKNQTSQRSRSIPVLSLKSTLKPLKRLSVKAAVVSQNSSKTVTKFDHCFKKSSDGFLYCEGTKVEDIMESVERRPFYLYSKPQITRNLEAYKEALEGVSSVIGYAIKANNNLKILEHLRSLGCGAVLVSGNELRLALRAGFDPTKCIFNGNGKSLEDLVLAAQEGVFVNVDSEFDLNNIVEASRISGKQVNVLLRINPDVDPQVHPYVATGNKNSKFGIRNEKLQWFLDQVKAHPKELKLVGAHCHLGSTITKVDIFRDAAVLMIEYIDEIRRQGFEVSYLNIGGGLGIDYYHAGAVLPTPMDLINTVRELVLSRDLNLIIEPGRSLIANTCCFVNHVTGVKTNGTKNFIVIDGSMAELIRPSLYDAYQHIELVSPPPAEAEVTKFDVVGPVCESADFLGKDRELPTPPQGAGLVVHDAGAYCMSMASTYNLKMRPPEYWVEEDGSITKIRHAETFDDHLRFFEGL
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase 1, chloroplastic, DAP decarboxylase 1, DAPDC 1.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KAD_PHEZH
Sequence: MNLILFGPPAAGKGTQAKRLVEQRRMVQLSTGDMLRAAIASGSELGQRVSGIMERGELVSDAIVIELIEQRLPEAEAAGGAIFDGFPRTLAQAEALDAMLAGRGRRIDLVVRLKVDDAALMQRIAGRFAESGRADDNPESFKVRLDAYNRQTAPLLPYYEGQGKLVEVDGMGSIDQVAAAIDAALTGAAA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAL1_PHAVU
Sequence: YIAGLLTGRPNSKAVGPSGVVLTAKQAFELANINSEFYELQPKEGLALVNGTAVGSGMASIVLFDANILAVLSEVLSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYMKDAKKLHEIDPLQKPKQDRYALRTSPQWLGPLIEVIRFSTKSIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVSMDNTRLALASIGKLMFAQFSELVNDFYNNGLPSNLTASRNPSLDYGFKGAEIAMASYCSELQYLANPVTSHVQSAEQHNQDVNSLDLISARKTNESIEILKLMSSTFLMGLCQAIDLRHLEENLKSSVKNTVSQVSKRTLTTGGNGELHPSRFCEKDLLKVVDREYVFSYIDDPYSGTYPLMQKLRQVLVDHALINAENEKDVNTSIFQKIATFEEELKTILPKEVESTRAAYESGKAAIPNKIKECRSYPLYKFVREELGTGLLTGEKVKSPGEEFDKLFTAICQGKIIDPLLECLGEWNGAPLPIC
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase class 1, Phenylalanine ammonia-lyase class I.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLD1_CHLCH
Sequence: MPNTILKLERIRKDLELSRSIRQTIIPNLSLSIERGEFVTITGPSGSGKSTLLYLMGGLDKPTSGSVWLDGDELTAKNESEMNRIRNEKIGFIYQFHFLLPEFTAVENVSMPMLINGRRSRKEIRDRAMMLLDLVELQDKYTNKPNQMSGGQQQRVAIARALANEPKVLLGDEPTGNLDSRSANNVYQLFDRLNRELQQTIIVVTHDEAFANRASRRIHLVDGQVAYDRQLRTEASVTNEAASLVS
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CCD14_HUMAN
Sequence: MKRGIRRDPFRKRKLGGRAKKVREPTAVNSFYREASLPSVWASLRRREMVRSGARPGQVLSSGRHTGPAKLTNGKKATYLRKIPRFNADSGYSIHSDSESQAETVHGLDGCASLLRDILRNEDSGSETAYLENRSNSRPLESKRYGSKKKRHEKHTIPLVVQKETSSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQMSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNTSPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIREATSERKDLNIHVRDTKTVKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPLRSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKDQTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNLTKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQDSDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSRASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDANIARLQKSLRTGLLEK
What is the function of this protein?
Negatively regulates centriole duplication.  Negatively regulates CEP63 and CDK2 centrosomal localization.
What are the official names of this protein?
Coiled-coil domain-containing protein 14.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Colocalizes with PCM1 at centriolar satellites throughout the cell cycle.
Protein: NALP_NEIMB
Sequence: MRTTPTFPTKTFKPTAMALAVATTLSACLGGGGGGTSAPDFNAGGTGIGSNSRATTAKSAAVSYAGIKNEMCKDRSMLCAGRDDVAVTDRDAKINAPPPNLHTGDFPNPNDAYKNLINLKPAIEAGYTGRGVEVGIVDTGESVGSISFPELYGRKEHGYNENYKNYTAYMRKEAPEDGGGKDIEASFDDEAVIETEAKPTDIRHVKEIGHIDLVSHIIGGRSVDGRPAGGIAPDATLHIMNTNDETKNEMMVAAIRNAWVKLGERGVRIVNNSFGTTSRAGTADLFQIANSEEQYRQALLDYSGGDKTDEGIRLMQQSDYGNLSYHIRNKNMLFIFSTGNDAQAQPNTYALLPFYEKDAQKGIITVAGVDRSGEKFKREMYGEPGTEPLEYGSNHCGITAMWCLSAPYEASVRFTRTNPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDNLRTTLLTTAQDIGAVGVDSKFGWGLLDAGKAMNGPASFPFGDFTADTKGTSDIAYSFRNDISGTGGLIKKGGSQLQLHGNNTYTGKTIIEGGSLVLYGNNKSDMRVETKGALIYNGAASGGSLNSDGIVYLADTDQSGANETVHIKGSLQLDGKGTLYTRLGKLLKVDGTAIIGGKLYMSARGKGAGYLNSTGRRVPFLSAAKIGQDYSFFTNIETDGGLLASLDSVEKTAGSEGDTLSYYVRRGNAARTASAAAHSAPAGLKHAVEQGGSNLENLMVELDASESSATPETVETAAADRTDMPGIRPYGATFRAAAAVQHANAADGVRIFNSLAATVYADSTAAHADMQGRRLKAVSDGLDHNGTGLRVIAQTQQDGGTWEQGGVEGKMRGSTQTVGIAAKTGENTTAAATLGMGRSTWSENSANAKTDSISLFAGIRHDAGDIGYLKGLFSYGRYKNSISRSTGADEHAEGSVNGTLMQLGALGGVNVPFAATGDLTVEGGLRYDLLKQDAFAEKGSALGWSGNSLTEGTLVGLAGLKLSQPLSDKAVLFATAGVERDLNGRDYTVTGGFTGATAATGKTGARNMPHTRLVAGLGADVEFGNGWNGLARYSYAGSKQYGNHSGRVGVGYRF
What is the function of this protein?
Plays a role in extracellular-DNA (eDNA) mediated biofilm formation.  In some strains (including cc32 strain MC58) eDNA stimulates biofilm formation.  When NalP is not expressed (and no longer processes NHBA or IgA) biofilm formation increases.
What are the official names of this protein?
Neisserial autotransporter lipoprotein NalP, Autotransporter NalP, NalP, Autotransporter serine protease A, AspA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: PTH_AYWBP
Sequence: MKLIVGLGNPGKKFLNTRHNIGFVVVDSFLSQNKYQTLKEDTNAHIYQINFNNHQTLLIKPQTYMNLSGEVVKKIINKYRIKIENILVIVDDIYLDEGKLKLKMQGGHGGHNGLRNIIDRLCTKQFKRLKIGVSLDSCMPLDQYLLTPVNASSQKNILKNIDIINKIIFNFIQDVDFNILMNGYNSKH
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.