PharMolix/UniProtQA huggingface dataset:
Protein: MYH1_PIG
Sequence: MSSDQEMAIFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESFVKGTVQSREGGKVTVKTEAGATLTVKEDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPELIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQGLNSADLLKALCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKVEAHFSLIHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSSVKTLAFLFTGAAGADAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQARCRGFLARVEYQKMVERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRTLEDQLSELKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHAVQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERSNAACAALDKKQRNFDKILAEWKQKYEETHAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHVRVVESMQSMLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVETVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-1, Myosin heavy chain 1, Myosin heavy chain 2x, MyHC-2x, Myosin heavy chain, skeletal muscle, adult 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: RHL_HYLPI
Sequence: MSSKYPRSVRGCLPLWALTLEAALILLFFFFTHYDASLEDQKGLVATYQVGQDLTVMAALGLGFLTSNLRRHSWSSVAFNLFMLALGVQWAILLDGFLSQFPPGKVVIKLLSIRLATMSAMSSLISVGAVLGKVNLVQLVVMVLVELTAFGTMRMVINNIFKTDYHVNIMHIHVFAAYFGLTVAWCLPKPPPEGTEDKEQIANSPSLSAMLGALFLWIFWPSFNSALLTNPIERKNAVFNTYYALAVSTVTAISVSSLAHPQGKINMTYMHNAVLAGGVAVGTSCHLISSPWLAMVLGLVAGLISIGGAKCLPDWLPDPLQHWGTQLGHGDSSHVWFPDRFAPKSQNMESTSCG
What is the function of this protein?
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
What are the official names of this protein?
RH-like protein, Rhesus-like protein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EFTS_TERTT
Sequence: MAVSASLVKELRERTGLGMMECKKALAETDGDIDAAIENLRKASGLKAAKKADRTAAEGVVAAKVADDGSYGVLVEVNSETDFVARDAGFLAFVDSVVEKAFSAKAADVAAVNDEAMESTRQALVQKIGENIGIRRVSLIEADGGLVGAYVHSNNRIAVMVQLANGGSVELAKDVAMHIAAVNPQVVNPEDMPEEVVNKEKDIIKAQPDMEGKPEQIVEKMMTGRINKFLKENSLVEQPFVKDPEITVGALVKKEGASVVSFSRFEVGEGIEKKEEDFAAEVAAQVAASKGNA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROCA_BACAN
Sequence: MVVAYKHEPFTDFSVEANKLAFEEGLKKVESYLGQDYPLIIGGEKITTEDKIVSVNPANKEELVGRVSKASRELAEKAMQVADETFQTWRKSKPEMRADILFRAAAIVRRRKHEFSAILVKEAGKPWNEADADTAEAIDFMEYYGRQMLKLKDGIPVESRPIEYNRFSYIPLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGVVNFVPGNGSEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGKDTIVVDKEADLELAAKSIVASAFGFSGQKCSACSRAVIHEDVYDHVLNRAVELTKELTVANPAVLGTNMGPVNDQAAFDKVMSYVAIGKEEGRILAGGEGDDSKGWFIQPTIVADVAEDARLMKEEIFGPVVAFCKAKDFDHALAIANNTEYGLTGAVISNNRDHIEKAREDFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLALHMQAKTTSETL
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: GSIC_SHIDS
Sequence: MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEADAQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLTITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELGWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEILLFSLEFILINLVVDVLYAAINPAIRYK
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BR1P_PELFU
Sequence: MFTLKKSLLVLFFLGTINLSLCEEERSADEEERRDEPNEMDVDVEKRFLPALIGIAAKALPSLLCKITKKC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Brevinin-1P.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PIGR_BOVIN
Sequence: MSRLFLACLLAIFPVVSMKSPIFGPEEVTSVEGRSVSIKCYYPPTSVNRHTRKYWCRQGAQGRCTTLISSEGYVSDDYVGRANLTNFPESGTFVVDISHLTHKDSGRYKCGLGISSRGLNFDVSLEVSQDPAQASHAHVYTVDLGRTVTINCPFTRANSEKRKSLCKKTIQDCFQVVDSTGYVSNSYKDRAHISILGTNTLVFSVVINRVKLSDAGMYVCQAGDDAKADKINIDLQVLEPEPELVYGDLRSSVTFDCSLGPEVANVPKFLCQKKNGGACNVVINTLGKKAQDFQGRIVSVPKDNGVFSVHITSLRKEDAGRYVCGAQPEGEPQDGWPVQAWQLFVNEETAIPASPSVVKGVRGGSVTVSCPYNPKDANSAKYWCHWEEAQNGRCPRLVESRGLIKEQYEGRLALLTEPGNGTYTVILNQLTDQDTGFYWCVTDGDTRWISTVELKVVQGEPSLKVPKNVTAWLGEPLKLSCHFPCKFYSFEKYWCKWSNRGCSALPTQNDGPSQAFVSCDQNSQVVSLNLDTVTKEDEGWYWCGVKEGPRYGETAAVYVAVESRVKGSQGAKQVKAAPAGAAIQSRAGEIQNKALLDPSFFAKESVKDAAGGPGAPADPGRPTGYSGSSKALVSTLVPLALVLVAGVVAIGVVRARHRKNVDRISIRSYRTDISMSDFENSRDFEGRDNMGASPEAQETSLGGKDEFATTTEDTVESKEPKKAKRSSKEEADEAFTTFLLQAKNLASAATQNGPTEA
What is the function of this protein?
Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens.  On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells.
What are the official names of this protein?
Polymeric immunoglobulin receptor, PIgR, Poly-Ig receptor.
What are the subcellular locations of this protein?
[Polymeric immunoglobulin receptor]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Secretory component]: Secreted.
Protein: RS19_RICFE
Sequence: MARSIWKGPFVDGYLIKKVQKLMESGKSEMIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNEEMVGRKLGEFAPTRTFHGHGADKKVKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ICA69_HUMAN
Sequence: MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELLNA
What is the function of this protein?
May play a role in neurotransmitter secretion.
What are the official names of this protein?
Islet cell autoantigen 1, 69 kDa islet cell autoantigen, ICA69, Islet cell autoantigen p69, ICAp69, p69.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Note=Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
Protein: ERF53_ARATH
Sequence: MATAKNKGKSIRVLGTSEAEKKDEMELEEEFQFSSGKYKDSGPGSDMWLGDASSTSPRSLRKTRTFDRHNPYLVSSYATPQPPTTTTCSVSFPFYLPPAIQNQQRFLHPNDPSGQRQQQMISFDPQQQVQPYVAQQQQQQQHLLQYWRDILKLSPSGRMMMMNMLRQESDLPLTRPPVQPFSATKLYRGVRQRHWGKWVAEIRKPRNRTRLWLGTFDTAEEAAMAYDREAFKLRGETARLNFPELFLNKQEPTPVHQKQCETGTTSEDSSRRGEDDSSTALAVGGVSEETGWAEAWFNAIPEEWGPGSPLWDDYHFPISNHKDDLDATQNSSSDTI
What is the function of this protein?
Transcriptional activator involved in abiotic stress tolerance.  Can directly regulate stress-related gene expression by binding to the DNA sequence 5'-[AG]CCGAC-3' (DRE element) of their promoter region.  Involved in the regulation of stomatal closure movement under drought stress (PubMed:23625358).  Acts as a positive regulator of drought stress response (PubMed:22095047).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF053, AtERF53.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CBPM_ECOSE
Sequence: MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: XPT1_YEAST
Sequence: MAENERMYISYNNIHKLCQGVAKHILARNERPDIIIAITGGGMIPARIIRSFLKTKGQKNIPIQAIGLSLYEDLGLDNSVETIGKEVIRTQWLDFGALNQHFDSLIGKKVLIVDEVDDTRTTLHYAVSELEKEIAEQQKVLNRMSEETVISIFVLHNKDKPKRAGLPDSMMNSGRYIAAQTVPDKWLCYPWDAEDIEEHTMLAKAQGHD
What is the function of this protein?
May act as a xanthine phosphoribosyltransferase involved in the synthesis of purine nucleotides.  Such activity is however unclear in vivo.
What are the official names of this protein?
Xanthine phosphoribosyltransferase 1, XPRT.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URER_ECOLX
Sequence: MEYKFFLSESQMVLKAFYIESAMIAMLTGAKGNIVINGQSIEIESDVTLIIPKYSQVSCNIVCNTVKQPLELHTLSMSAEELQAVFLLLKTLMKSGAPLTSHQPIYHISPPETVRDNFSLLKQCLPLKKQSASQEALLMKQSLYFILMAIYQEGIDILNLFRFNYDEPKNQAITHLITQEPQKKWHLDDVAKALFTTPSTLRRHLNREGVSFRQLLLDVRMGMALNYLTFSNYSVFQISHRCGFGSNAYFCDVFKRKYNMTPSQFRLQSRQSNDPNFITNLSLRSNPIEFDKEIDE
What is the function of this protein?
Positive regulator of the expression of the urease operon.
What are the official names of this protein?
Urease operon transcriptional activator.
Protein: SSPO_BACAC
Sequence: MGKRKANHTISGMNAASAQGQGAGYNEEFANENLTPAERQNNKKRKKNQ
What are the official names of this protein?
Small, acid-soluble spore protein O, SASP O.
What is the protein family that this protein belongs to?
Belongs to the SspO family.
What are the subcellular locations of this protein?
Spore core.
Protein: NUSA_THEAC
Sequence: MEMNEITVDNETMAHIAIFEKIARIELMECVENEDMILFVVGEHKMAEMFRKNKEVISQLKEKINKHILVAEVSRDLLTFVRNIFFRYGVNEIQISWKNNRTDIVVGVKPEEIGKVIGKEGKNIKLFKDAVSRYFNVNSISVKQ
What is the function of this protein?
Participates in transcription termination.
What are the official names of this protein?
Probable transcription termination protein NusA.
What is the protein family that this protein belongs to?
Belongs to the NusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU131_SCHPO
Sequence: MFIVHRRFFQNEKAFTPAGKHEKVADGNKHETLATSEYPKVCASNDLYKILQISAPKVGNFTIHDAPVVGLIDSILEYYLYISVKVRKAWIAGYGSQPQNLICFDWERFTGILDQQSLNSPPLAGFVKPDPTSAEPGFLLLWPASGDLFYWERTSLMNVEVSAPEFPGFLHYRIQLKRYESCKNLVSAEPAGFFLTLSSGRLLHLNLKDSDGNSSIQVRILFPGLHIPNCLLSLYNSIFAFTSGRVIPIRCGSIKGPGERLVYSMHSGSTLRIWEIFGTGDHHLLRGFDIYDIILDSIQESFSYVNRFLILDFSVSTSDPYTLACLVSWRDNASLFNYAAIIISFNHQMIPHVSQFCHVRSYLSAILPSVCRIFLPSPGTVVFCVFDVTFAMFHKVRGKEGTFYVEENLVVNNLTSKSRVLDFGMEDAIYEKSTHTLLKTPALILLTEGHGIIRIESSASYLKTSFSATTYLRSRLSQFASQSPLFREQFLLNFDFTYNLSESEVYNTVFNLCDELYTTPCKKNMSVLETLHSQQRDLMEIVLVAFKYLHLSPSNRLQLWLKVAYCSALADLYELLMCNEKMSNLLRRVLKIMSSNDNIDELFLKKCLNINLLLQHLSSEYSQISGQDASNAQKRIEVIVNVNNVYGTIFGNELAYRQEKISKFTDPSSVIRSDLWTVEVDHLDLLRKQIEDSISLHRDVRDSKDAHILKVSNKLRKQILHLVEQNCLLIFDLHNGTDDTIVKSHNFQKFEEEFGNSRKEWLQYLASVGYLEKAIDLAEKVKDFQTMVILLDCLDPKDPTIKLQKQKACLNKYKEEFADVIFFYLVDTEQYASLLHDFLEYQSLLISFFEANDLLNLLWIFEAQNGNYGRASEILFRDCEPEENRIIGKISQLALAKLYSWTNRIEGENIILSNETEVIENHLAILLIQEQYAEMLSSLVDITEDEGEAVEAIVTSNCVNLSENSIRAWLVSSAVERLIQNEYTTLCEMVDFFSSFSLRECSFKEVDLALELLERATITKDVYFYLKDLVYRRFLLQVNWAEIIDAHEDLESSFFPMVKEIMLESDFLIWLQHMEHNIHDESKHYLKSEKNFLQSVYSSLSESQVEDYQMELFREKQIFSVLCKDRELYILIPKLLDVATKQ
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.
What are the official names of this protein?
Nucleoporin nup131, Nuclear pore protein nup131.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin Nup133 family.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear rim.
Protein: MSRB3_ORYSJ
Sequence: MGVQHLLKLRMASPHPHPHPGAPLAARPLSALASFFLARPSSTAAAPPPRHVTLSCSRPHCNHNQWAASRCRGTAGRRRLQVVVAMSSSAPPPPPGSVQKSEEEWEAILSPEQFRILRLKGTEYPGTGEYDKLFAEGVYECAGCGTPLYKSSTKFNSGCGWPAFYEGFPGAIARTPDPDGRRIEITCAACGGHLGHVFKGEGFNTPTDERHCVNSISLKFIPASEDSKL
What is the function of this protein?
Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins.  Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation.  MSRB family specifically reduces the MetSO R-enantiomer (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase B3, chloroplastic, OsMSRB3, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RN128_BOVIN
Sequence: MGQLPGAGVFCRGGCGFSRLLAWCFLLVLSPQTPGSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVPGDWGSSVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAGDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTQKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHVFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNETSSNASPHEEDNRSETASSGYASVQGADEPPLEEHAHSANENLQLVNHEANSMAVDVVPHVDNPTFEEDESPDQETTVREIKS
What is the function of this protein?
E3 ubiquitin-protein ligase that catalyzes 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains formation.  Functions as an inhibitor of cytokine gene transcription.  Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production.  Ubiquitinates ARPC5 with 'Lys-48' linkages and COR1A with 'Lys-63' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse.  Functions in the patterning of the dorsal ectoderm; sensitizes ectoderm to respond to neural-inducing signals.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF128, RING finger protein 128, RING-type E3 ubiquitin transferase RNF128.
What are the subcellular locations of this protein?
Endomembrane system; Single-pass membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Note=Localized in an asymmetric perinuclear punctate manner. Localizes to the internal pool of the transferrin recycling endosomal pathway. Partially colocalized with the endoplasmic reticulum resident HSPA5, with Golgi resident STX5, and with the late endosomal GTPase RAB7A.
Protein: RS11_MICLC
Sequence: MPPKTRASAARKPRRKANKNITVGQAHIKSTFNNTIVSITDTTGAVISWASSGEVGFKGSRKSTPYAAQMAAEQAAKRAQEHGMKKVDVFVKGPGSGRETAIRSLQAAGLEVGSIQDVTPMAHNGARPAKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CARX_BACSU
Sequence: MEGYLVLEDGTSFSGELDGHENCTGEAVFFTGMTGYQEVLTDPSYKGQIIVFTYPLIGNYGINEKDFESKKPQVKAAVVYEACDHFSHYEAVYSLKEYLQKWNIPLLTHVDTRAVVKKIRANGTMGATVTASKEGAEIALQPENVAEQASAQEISTFGDGNKHIALIDFGYKKSIASSLVKRGCKVTVVPYQQMEAVYNIKPDGIVLSNGPGDPKAIQPYLGKIKSIISRFPTLGICLGHQLIALAFGGNTFKLPFGHRGANHPVIDRKTKRVFMTSQNHSYVVDEQSINEEELTIRFHHVNDTSVEGLAHKKLPVMSVQFHPEAHPGPAESEWIFDDYLKNVIPARREIAHA
What are the official names of this protein?
Carbamoyl-phosphate synthase arginine-specific small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: RS7_CYTH3
Sequence: MRKAKPKKRYLLPDPKFSDTMVTKFVNSLMYDGKKSTAYSIFYDAVALVEKKTSESGLEVWKKALNNVSPQVEVRSRRVGGSTFQVPTEVRPDRKMALGMKWLINYARSRGEKTMTDKLAGEIISASKGEGAAVKKRDDVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CBPN_BOVIN
Sequence: MSDLVSIFLHLLLFKLVAPVTFRHHRYDDLVRMLYKVHNECPHITRVYSIGRSVKGRHLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRIVRLVEDTRIHIMPSMNPDGYEVAAAAQERDISGYLVGRNNANGVDLNRNFPDLNTYIYYNEKNGGPNHHFPLPDNWKSQVEPETQAVIQWIRSFNFVLSANLHGGAVVANYPYDKSLGHRVRGFRRTANTPTPDDKLFQKLAKIYSYAHGWMHQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPLQGELQREWLGNREALIQFLEQVHQGIKGMVRDENYNNLADAVISVGGINHDVTSGAHGDYFRLLLPGTYTVTATAPGFDPETVSVTVGPAEPKLVNFQLKRSTPQAAPKRRIPNSGHRGRVLPKKVQPRAARKKETMMKQPQRGPA
What is the function of this protein?
Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
What are the official names of this protein?
Carboxypeptidase N catalytic chain, CPN, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: DCR1_DICDI
Sequence: MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN
What is the function of this protein?
May be required for DNA interstrand cross-link repair.
What are the official names of this protein?
DNA cross-link repair 1 protein.
What is the protein family that this protein belongs to?
Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENO_BORRA
Sequence: MGFHIYEIKARQIIDSRGNPTVEADVILEDGTLGRAAVPSGASTGTNEAVELRDGDKSVYMGKGVLKAVENIINIISPELEGMSALNQVEIDRKMLELDGTPNKSKLGTNAILAVSMATARAAAEHLGLKVYQYLGTYKANILPTPMCNIINGGAHSDNSVDFQEFMIMPIGAKTFSDAIRMSAEVFHTLKSILSKKGYATSVGDEGGFAPNLKSNEEACEVIMEAIKSAGYTPGTDIAIALDPATSELYDPKTKKYVFKWSTKEELTSQEMVEYWAKWVEKYPIISIEDGMAEEDWDGWKKLTDKIGNKIQLVGDDLFVTNTSFLKKGIEMKVANAILIKVNQIGTLTETFEAVEMAKKAGYTAIVSHRSGETEDTTIADLVVALGTGQIKTGSLSRTDRIAKYNQLLRIEEELGSIAEYHGKDVFYSINK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: IF2_PSEMY
Sequence: MTQVTVKELAKVVDTPVERLLQQMREAGLSHDNAEQVVTDSEKQALLAHLKSSHGDKVEEPRKITLQRKTTSTLRVAGSKTISVEVRKKKTFVKRSPEELEAEKQRELEAQRAEAEAERLKAEEEAKRKAEEEAKRQAAAATSEAPAPAASPAPLSEPVVAAPVVEVERKKEEVRRPEKARSDEDERRDRKHAQHRPTLKEKAPAPRVAPRSVDEESDGFRRGGRGKAKMKKRNQHGFQAPAGPVVRDVAIGETITVADLAQQMSIKAAEVIKFMFKMGTPVTINQVLDQETAQLVAEEFGHKVKLVSDNALEEQLAESLKFEGEAMSRAPVVTVMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETDRGMVTFLDTPGHAAFTAMRARGAKATDIVILVVAADDGVMPQTQEAVQHAKAAGVPIVVAVNKMDKPEANPDNIKNGLAALDVIPEEWGGDAPFVPVSAKAGTGIDELLEAVLLQAEVLELKATPTAPGRGVVVESRLDKGRGPVATVLVQDGTLRQGDMVLVGVNYGRVRAMLDENGKPIKEAGPSIPVEILGLDGTPDAGDEMMVVADEKKAREVALFRQGKFREVKLARAHAGKLENIFESMGQEEKKTLNIVLKADVRGSLEALQGSLSTLGNDEVQVRVVGGGVGGITESDANLALASNAVLFGFNVRADAGARKIVESEGLDMRYYNVIYDIIEDVKKALTGMLGSDVRENILGTAEVRDVFRSPKFGAVAGCMVIEGTVYRNRPIRVLREDVVIFEGELESLRRFKDDVAEVRNGMECGIGVKSYNDVKVGDKIEVFEKVQVARSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.