PharMolix/UniProtQA huggingface dataset:
Protein: EMBB_MYCSM
Sequence: MSGNMDEAVSGNMDEAVSAGKDVRIARWVATIAGLLGFVLSVSIPLLPVTQTTATLNWPQQGRLDNVTAPLISQAPLELTATVPCSVVRDLPPEGGLVFGTAPAEGRDAALNAMLVNVTETRVDVIVRNVVVASVNRDRVAGPDCQRIEITSNLDGTYADFVGLTQISGEDAGKLQRTGYPDPNLRPAIVGVFTDLTGPAPQGLSVSAEIDTRFTTHPTALKLAAMLLAIVSTVIALLALWRLDRLDGRRMHRLIPTRWRTVTAVDGVVVGGMAIWYVIGANSSDDGYILQMARTAEHAGYMANYFRWFGSPEDPFGWYYNVLALMTKVSDASIWIRLPDLICALICWLLLSREVLPRLGPAVAGSRAAMWAAGLVLLGAWMPFNNGLRPEGQIATGALITYVLIERAVTSGRLTPAALAITTAAFTLGIQPTGLIAVAALLAGGRPILRIVIRRRRLDGTWPLIAPLLAAGTVILAVVFADQTIATVLEATRIRTAIGPSQEWWTEKLRYYYLILPTTDGAISRRVAFVFTAMCLFPSLFMMLRRKHIAGVARGPAWRLMGIIFATMFFLMFTPTKWTHHFGLFAAVGGAMAALATVLVSPTVLRSARNRMAFLSLVLFVLAFCFASTNGWWYVSNFGAPFNNSVPKVGGVQISAIFFALSAIAALWAFWLHLTRRTESRVVDRLTAAPIPVAAGFMVVVMMASMAIGVVRQYPTYSNGWANIRAFAGGCGLADDVLVEPDSNAGFLTPLPGAYGPLGPLGGEDPQGFSPDGVPDRIIAEAIRLNNPQPGTDYDWNRPIKLDEPGINGSTVPLPYGLDPKRVPVAGTYSTEAQQESRLSSAWYELPARDETERAAHPLVVITAAGTITGESVANGLTTGQTVDLEYATRGPDGTLVPAGRVTPYDVGPTPSWRNLRYPRSEIPDDAVAVRVVAEDLSLSQGDWIAVTPPRVPELQSVQEYVGSDQPVLMDWAVGLAFPCQQPMLHANGVTEVPKFRISPDYYAKLQSTDTWQDGINGGLLGITDLLLRASVMSTYLSQDWGQDWGSLRKFDTVVEATPAELDFGSQTHSGLYSPGPLRIRP
What is the function of this protein?
Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
What are the official names of this protein?
Probable arabinosyltransferase B.
What is the protein family that this protein belongs to?
Belongs to the emb family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CD048_HUMAN
Sequence: MAPPPACRSPMSPPPPPLLLLLLSLALLGARARAEPAGSAVPAQSRPCVDCHAFEFMQRALQDLRKTACSLDARTETLLLQAERRALCACWPAGH
What are the official names of this protein?
Neuropeptide-like protein C4orf48.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBI_PROMM
Sequence: MLALKLSVYSVVFFFIAVFVFGFLASDPSRTPARKDLED
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: Y1465_ARATH
Sequence: MVDEDRITLAPTEIYGRSDEEQSGPRIWRRKTEEPPGKCLVYSLTIIVIIFALCLILSSIFLRISKPEIETRSISTRDLRSGGNSTNPYFNATLVSDISIRNSNFGAFEFEDSTLRVVYADHGVVGETKIEGRRVEAHKTVRITGVVVEIGSFRLLDTKDLDKDLRLGFLELRSVAEVRGRIKVLGRKRWKVSVMSCTMRLNLTGRFIQNLLCE
What are the official names of this protein?
Late embryogenesis abundant protein At1g64065.
What is the protein family that this protein belongs to?
Belongs to the LEA type 2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PURA_CUTAK
Sequence: MPGIVVMGTQWGDEGKGKATDLMSERVDYCVRYSGGNNAGHTVVVGDEKFFMHLLPSGVLNPNSTAVLGNGVVLNLDVLADEIDALRGRGVDIPHPLISANAHLITPYHQTLDKVTERFLGSRRIGTTGRGIGPTYSDKINRMGIRVQDLFDESILRQKVEASLDQKNQILVKIYNRRAIDPGEVADGLLAHAERIRPYVVDVARVLNKGLDEGKVVLFEGAQAHHLDVDFGTYPYVTSSNPIAAGACTGSGVGPTRIDRIVGIAKAYTTRVGEGPFPTELCDDDGERLRSEGGEYGVTTKRPRRCGWFDALVVQQAVMINSVTDLFLTKLDVLTGWERIPVCVGYDIDGERTDIMPVTQSDLHHAKPVYEFLDGWSEDISTARSFDDLPRNCQAYVRRLEELVGTRVSGIGVGAGRDESVVINDLID
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_CAMJJ
Sequence: MKTSILILAAGLGTRIKSQKPKVLQELCQKSMILHILKKAFALSDDVSVVLSHQKERVEKEILEYFPKTQILEQDLQNYPGTAGALSGFEPKNERVLILCGDMPLVEQTSLEALLSNNAKLNLAVFKARDPKSYGRVVIKNDSVEKIVEFKDANTQEKEINTCNAGVYVIDSRLLKELLPLIDNNNAAKEYYLTDIVKLAKEKDVMIKAVFVDEDEFMGINDKFELSIAENFMQEKIKKYWMQQGVIFHLPQSTFIGADVEFVGECEVYENVRIEGKSKIINSIIKSSSVIENSIVENSDVGPLAHLRPNCELKNTHIGNFVECKNAKLNTVKAGHLSYLGDCEIDSGTNIGCGTITCNYDGVKKHKTIIGKNVFVGSDTQFIAPVKIEDEVIIAAGSTVSVNVEKGALFINRAEHKMIKDYYYKKFQK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRCC3_CALJA
Sequence: MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMRTVAEKVDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSESLHGPRDFWSSSKHISIEGQKEEERYERIEIPIHIVPHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLRELQQEKEELMQELSSLE
What is the function of this protein?
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains.  Does not have activity toward 'Lys-48'-linked polyubiquitin chains.  Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).  In the BRCA1-A complex, it specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the RNF8-dependent ubiquitination at double-strand breaks (DSBs).  Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates.  Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex.  The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.  Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression (By similarity).  Acts as a regulator of the NLRP3 inflammasome by mediating deubiquitination of NLRP3, leading to NLRP3 inflammasome assembly (By similarity).  Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (By similarity).  Deubiquitinates HDAC1 and PWWP2B leading to their stabilization (By similarity).
What are the official names of this protein?
Lys-63-specific deubiquitinase BRCC36, BRCA1-A complex subunit BRCC36, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRISC complex subunit BRCC36.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. BRCC36 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs). Interaction with ABRAXAS2 retains BRCC3 in the cytoplasm.
Protein: RRF_CORU7
Sequence: MMDEILLECEERMTSSVEFAREDLTTIRTGRANPAMFNSVIAEYYGVPTPITQMATISVPEARMMLIKPYEQSQIQVIENAIRNSDLGVNPTNDGQVLRVTIPQLTEERRREMVRQAKSKGEDAKIAIRNIRRHGMEQLAKIQKDGDAGEDEVRASENELEKITSNYVKQVDELVERKEEELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_MALP2
Sequence: MSKIVKQEENFSKWYTSIIENANLVDYGLVKGTIMFKPYGFAIWKRIQEEFNKILVSLNTAEVCFPMLIPYSEFMKEKEHVEGFNPELFKVSHLGEKKLEDELVIRPTSEISFCNYFKKNIKSYNDLPCILNQWGSVFRVEKNTRPFLRTSEFLWQEQHAVFADKKEAFDFSITMVNEYKKFVNDYLSIAVLMGEKTENERFAGADNTFTIEALMPDGQVLQSATSHYLGTNFAKSYDLKYQTKNNNYDLMFQTSAGLSTRIIGAIIMSHSDNNGLVLPFKIAPIQFAIVTSNEVNKDSDELKAIYKNLFGYKYQTYFVEKSLGLQLQENEIKGIPFQLILGKKEIENNTITIYRRDTREKQNISFKEFNQNFIENLIKEYSSNLFNKTEKRLNSSIEFVNNIDEFKKALDNKKIISAYWSGNAEDEKKLKELTTATPRCFDWNQKIDKTKKCFFTNKPNAKLVYFARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_CLOPS
Sequence: MFKKADRKEARERRHLRVRKKVFGTPERPRLSVYRSEKNIYAQIIDDVNAVTLVAASSLDKAIEVKGSNKEAAKLVGELVAKRAIEKGINDVVFDRGGYVYHGRVEALASGAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RAB1B_RAT
Sequence: MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTVTSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGERPNLKIDSTPVKSASGGCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity).  Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum (By similarity).  Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments (PubMed:1918138).  Required to modulate the compacted morphology of the Golgi.  Promotes the recruitment of lipid phosphatase MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment (PubMed:23188820).
What are the official names of this protein?
Ras-related protein Rab-1B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor; Cytoplasmic side. Preautophagosomal structure membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Targeted by REP1 to membranes of specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between these two compartments. In the GDP-form, colocalizes with GDI in the cytoplasm (By similarity). Co-localizes with MTMR6 to the endoplasmic reticulum- Golgi intermediate compartment and to the peri-Golgi region (PubMed:23188820).
Protein: HIS2_BURMS
Sequence: MTQSTTEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAILKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLVALSHFDLSPADVIAELERREGMSGIEEKALRKRREREENGG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCL10_HUMAN
Sequence: MEPTAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFPDGATNNLSRSNSDESNFSEKLRASTVMYHPEGESSTTPFFSTNSSLNLPVLEVGRTENTIFSSTTLPRPGDPGAPPLPPDLQLEEEGTCANSSEMFLPLRSRTVSRQ
What is the function of this protein?
Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation (PubMed:10187770, PubMed:10364242, PubMed:10400625, PubMed:25365219, PubMed:24074955).  Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing proteins CARD9, CARD11 and CARD14 to activate NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines (PubMed:24074955).  Recruited by activated CARD domain-containing proteins: homooligomerized CARD domain-containing proteins form a nucleating helical template that recruits BCL10 via CARD-CARD interaction, thereby promoting polymerization of BCL10, subsequent recruitment of MALT1 and formation of a CBM complex (PubMed:24074955).  This leads to activation of NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines (PubMed:18287044, PubMed:27777308, PubMed:24074955).  Activated by CARD9 downstream of C-type lectin receptors; CARD9-mediated signals are essential for antifungal immunity (PubMed:26488816).  Activated by CARD11 downstream of T-cell receptor (TCR) and B-cell receptor (BCR) (PubMed:18264101, PubMed:18287044, PubMed:27777308, PubMed:24074955).  Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK (PubMed:10187815).
What are the official names of this protein?
B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, Cellular homolog of vCARMEN, cCARMEN, Cellular-E10, c-E10, Mammalian CARD-containing adapter molecule E10, mE10.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Membrane raft. Note=Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts.
Protein: LGI1_PONAB
Sequence: MESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGGFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIETQLYVIVAQLFGGSHIYKRDSFANKFIKIQDIEILKIRKPNDIETFKIENNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIVRTPQTLRTPHLILSSSSQRPVIYQWNKATQLFTNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQICKHVIVDLSA
What is the function of this protein?
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1.  It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit.  Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors.  Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity).
What are the official names of this protein?
Leucine-rich glioma-inactivated protein 1.
What are the subcellular locations of this protein?
Secreted. Synapse.
Protein: CST10_ARATH
Sequence: MSYQDPQHPVSAPPPQGYPPKEGYPPAGYPPPAGYPPPQYPQAGYPPAGYPPPQQGYGQGYPAQGYPPPQYPQGHPPQYPYQGPPPPHYGQAPPKNKKDKKDSGGFMEGCLAMLCCCVLLEACF
What is the function of this protein?
Involved in resistance to abiotic stress.
What are the official names of this protein?
Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 10, AthCYSTM10, Protein WINDHOSE 3.
What is the protein family that this protein belongs to?
Belongs to the CYSTM1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cytoplasm.
Protein: MQNX_STRAW
Sequence: MTEHFDARGTRDAQTGRDLHSFIAGLPKAELHVHHVGSASPRIVSELAARHPDSSVPTDPEALADYFTFTDFAHFIKVYLSVVDLIRTPEDVRLLTYEVARELARQQVRYAELTITPFSSTRRGIDERAFMDAIEDARKSAEAEFGTVLRWCFDIPGEAGLESAEETVRLATDDRLRPEGLVSFGLGGPEIGVPRPQFKPYFDRAIAAGLRSVPHAGETTGPETVWDALTDLRAERIGHGTSSAQDPKLLAHLAEHRIPLEVCPTSNIATRAVRTLDEHPVKEFVRAGVVVTINSDDPPMFGTDLNNEYAIAARLLDLDERGLAGLAKNSVEASFLDAAGKARIAAEIDTYTAAWLAP
What is the function of this protein?
Catalyzes the deamination of aminodeoxyfutalosine (AFL) into futalosine (FL), a step in the biosynthesis of menaquinone (MK, vitamin K2).  To a lesser extent, can also deaminate adenosine, 5'-methylthioadenosine, 5'-deoxyadenosine, and 2'-deoxyadenosine.
What are the official names of this protein?
Aminodeoxyfutalosine deaminase, AFL deaminase, Aminofutalosine deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: SPLC_STAAW
Sequence: MNKNIVIKSMAALAILTSVTGINAAVVEETQQIANAEKNVTQVKDTNIFPYNGVVSFKDATGFVIGKNTIITNKHVSKDYKVGDRITAHPDGDKGNGGIYKIKSISDYPGDEDISVMNIEEQAVERGPKGFNFNENVQALNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDNILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ
What are the official names of this protein?
Serine protease SplC.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNC_VIBA3
Sequence: MNSPIDKLERKIGYQFNDADLIHLALTHRSAAGKHNERLEFLGDSILSFVIADDLYHRFPKVNEGDMSRMRATLVRGHTLAELGREFELGDYLKLGPGELKSGGFRRDSILADAVEAIIGAVYLDSDTEVVRRIILSWYQSRLESIQPGVSQKDPKTRLQEFLQGRRNPLPVYTVTNIKGEAHNQEFTVECEVAGVDKPVIGKGTSRRKAEQAAAETALEQLSNV
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_SALNS
Sequence: MSKPFKLNSAFKPSGDQPDAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQVESTVPRYTIYPKTHYVTPRERILQAMEEIKDELADRRKVLLANNKLLEEQRLSQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGDEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGKGKGRSTAKAGIVELDMTPKALQQKIHELEGQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_SULIA
Sequence: MRVKIVSKPTSQLNNIIEKIKNISTKLGFEVVDKDFDYVIAVGGDGTLLRAVKQNKPVIAVKAGRRGLLMDVPVDKFEEALLRLKKGDYEEEEYMLLEMIYNDKVELGFNEVGILYDRPEAIKVGISFDTERVSVEGDGVLVSTPQGSSGWGMSATNSLLYKDLSAIEIIFVNPIFYYLRSVVIPPKPLTLRLEDKGYPQTARAVVDGEVVTLIKTNQEITVRVSQRKAKILRFFKLDLIGEVLHAYHI
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_ECOL6
Sequence: MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: VPRL_OMVVS
Sequence: MEEAPRRRPGGSREAEGIFRYYEDWECWDHVSQRVPNEVLQRWLAMLTNNQLRRKVIREAQIWMWKNANAPIRRNCGCRLCNPGWGSQVRDVEL
What is the function of this protein?
Seems to function as a Vpr-like protein, since it mediates host cell cycle arrest in G2 phase.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production (By similarity).
What are the official names of this protein?
Probable Vpr-like protein, Protein S, Protein Tat.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: HIS6_CAUVC
Sequence: MLKTRIIPCLDVKDGRVVKGVNFVSLRDAGDPVEQARAYDAAGADELMFLDITASSEGRGLILDVISRTAEVCFMPVSVGGGVRQVSDMRRLLLAGADKVSVNTAAVENPDLIAGGADAFGSQCVVVAIDAKAREDGSGWNVWTYGGRKDTGIDVVEWAAKVVERGAGEILLTSMDRDGAKIGYDIPLLQAVTGAVNVPVIASGGAGKTEHLIEAAREGHAAAVLAASIFHFGEISIGEAKQAMADAGIPVRLDALKGAA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_CUPTR
Sequence: MRNRILVSACAALAMFAMQAPAHAAATDQLQSFVTGVKSARGEFTQRQVKGQGANVKVTGTSSGTFVFSRPGKFTWRYTKPYEQLLQADGQTLYIYDKDLNQVTERKLDGALGSSPAAILFGSNDLDKNFVVRNGPTRDGVEWLELTPKAKDTQFERIGIGFKAGNLEAMELRDAFGNTTLLTFTGMQKNPPLAADAFRFTVPKGADVMKQ
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.