PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_NEOSM
Sequence: MRNSIFEQEETFQDLSLRPKSIEKFVGQQRVVENLQVFIDSAQKRNDSLDHVLFCGPPGLGKTTLAHIISNELESRIHTTAGPLLSKAGDIAAILTNLHKNDILFIDEIHRLPSAVEEVLYPAMEDYHLDLIVGDGPAAKSIRINLAKFTLVAATTRIGMLSNPLRDRFGITLRLDFYTVSELLQLLQQAAERLSVNIENGAMIELAKRSRGTPRIALRLLKRVRDFLEVSDSDVITREFADLALNKMEVDQFGLDKLDYTYMDFIAKNYSDNPVGIKTIAAAISEKEDSIEELIEPYLIKIGFLSRTQRGRRLTGKALDYLSTINSARLP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HSE1_NEOFI
Sequence: MFRAQQNAFDDAVAKATDENLTSENWEYILDVCDKVAAEESGAKDAVAAMIKRLAHRNANVQLYTLELANALAQNCGPKIHRELASRSFTDALLRLANDRNTHQQVKPKILERMQEWAQMFANNPDFGIMEQAYMKLKTQNPNLQPPSKPGKREITEADRQKEEEELQMALALSIREKPSAAPEPKAEPSTSASVPASQTQAATSQAVPPGTSAATVSRVRALFDFQPSEPGELQFRKGDIIAVLESVYKDWWKGSLRGQTGIFPLNYVEKLPDPTVEELQREAQMEAEVFGQIKNVEKLLTLLSTRSSELNVQDNEEITALYHSTLSIRPKLIELIGKYSQKKDEFTQLNEKFIKARRDYESLLEASMSHPAQPQYGRPGQTPYGYPGPAAPLGYPQGPPQSDPQRYFSPRPQDQTHMYPPTSHSPDPRGRTPPAGPSFPQHQQPPPDSYQPVHHRPESTYDNPQELGTSVYDSPVEHPSSSQRLPYPPSGAPVPPGVHQQFQHQQQEYPPSGYPPEDASKPPTAGFASQPPQQTLQQPPYPTAPVAHQPPPSHQPPPVPSTASKPTPYPSLTPGTPSGGEYQAYNPSQAGAANSNPNSYYR
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
What are the official names of this protein?
Class E vacuolar protein-sorting machinery protein hse1.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYFA_CERSK
Sequence: MTALDTLRGKYIEAIASAADEAALEEVRLAALGKKGEISLKMRELGQMSPEERQTTGAALNRLRDEIDASLRARKQGLADAALDARLKTEWLDVTLPGRPRRAGTIHPVSQVMAELTAIFSDMGFAVAEGPQVESDWFNFDALNIPPEHPARQEHDTFFMARAEGDDRPPHVLRTHTSPVQIRAMQAQGAPIRVIAPGRVYRMDMDQTHTPMFHQVEGLAIDRDISMANLKWVLEEFCRAFFEVPSVELRFRASHFPFTEPSAEVDIRCSWEGGQLRIGEGDGWLEILGSGMVHPKVLAAAGVNPDEWQGFAFGMGIDRIAMLKYGIPDLRAFFESDLRWLRHYGFAALDMPDLAGGLSR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBV2_THEVB
Sequence: MYQPHFWQRSIGWLCGGLLILLLGWTIAPATALAAAGVDNYVIQYLKVTDTVELPVNDRGETKTFTAVDLTRGKRLFEENCKNCHVGGSTLPNPLVSLSLKDLKGATPPRDTIASLVAFQRSPKSYDGSEESYSCRRVSEDWLTTEQLETLAAFILRAAAVAPGWGVESFPDSAP
What is the function of this protein?
Can partially replace cytochrome c-550 (PsbV) function.
What are the official names of this protein?
Cytochrome c-550-like protein.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: TBB_SCHCO
Sequence: MREIVHLQTGQCGNQIGAKFWEVVSDEHGIEADGLYKGTNDQQLERISVYYNEIGANKYVPRAILVDLEPGTMDSVRSGPLGGLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAEGTDCLQGFQITHSLGGGTGAGMGTLLISKIREEYPDRMMCTFSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICFRTLKLSTPTYGDLNHLVSFVMSGITTSLRFPGQLNSDLRKLAVNLVPFPRLHFFMTGFAPLTARGSQQYRAVTVPELTQQMFDAKNMMAASDPRHGRYLTVAAMFRGKVSMKEVEEQMQNVQNKNSAYFVEWIPNNVLASQCDIAPRGLRMSVTFLGNSTAIQELFKRVSDQFTAMFKRKAFLHWYTQEGMDEMEFTEAESNMQDLVAEYQQYQDATVEEEGEYEEEVIEDQE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HIKES_XENLA
Sequence: MFGCLVAGRLVQTDAQQVAEDKFVFNLPDFESINHVVVFMLGTVPFPERMGGSVYFSFPDQTGMPVWTLLGFITNEKPSAIFKISGLKSGEGSQHPFGTMNLPQTPSVAQIGISVELLEQMAQQTPVANAAVSTVDSFTQFTQKMLDNFYNFATSFAVSQAQMIPNPSEVFIPSNVVLKWYENFQRRMAQNPFFWKT
What is the function of this protein?
Acts as a specific nuclear import carrier for hsp70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound hsp70 proteins into the nucleus.  hsp70 proteins import is required to protect cells from heat shock damages (By similarity).
What are the official names of this protein?
Protein Hikeshi.
What is the protein family that this protein belongs to?
Belongs to the OPI10 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: MURD_STRP4
Sequence: MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTEVELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATDKNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAADFLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYC_HRSV2
Sequence: MSKNKDQRTAKTLERTWDTLNHLLFISSCLYKLNLKSVAQITLSILAMIISTSLIIAAIIFIASANHRVTSTTTIIQDATNQIKNTTPTYLTQNPQLGISPSNPSEITSLITTILDPTTPGVKLTLQSTTVRIKNTTTTQAQPNKSTTKQRQNKPPSKPNNDFHFEVFNFVPCSICSNNPTCWAICKRIPNKKPGKRTTTKPTKKPTLKTTKKDPKPQTTKSEEVPTTKLTEEPTINTTKTNIITTPLTSNTARNPELTSQMETFHSTSSEGNPSPSQVSITSEYPPQPSSPPNTPR
What is the function of this protein?
Helps the virus escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fc-gamma receptors.
What are the official names of this protein?
Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG.
What is the protein family that this protein belongs to?
Belongs to the pneumoviruses glycoprotein G family.
What are the subcellular locations of this protein?
[Isoform Membrane-bound glycoprotein G]: Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform Secreted glycoprotein G]: Secreted. Note=The protein is shed from infected cells before the appearance of progeny virus. The initiation at the downstream methionine removes a portion of the transmembrane domain. The remaining hydrophobic portion of the sG protein is essential for translocating it into the lumen of the ER during translation and would likely maintain its membrane association until a proteolytic event releases the mature sG protein into the medium.
Protein: FABZ_COXBN
Sequence: MNITDIKKYIPHRYPFLLIDRVIKIEKDKSLVAIKNVTVNEPFFTGHFPVRPVMPGVLIIESLAQAAGILIVKSLNLPEGHKDIYFFAGVDNARFKRVVEPGDQLTLEVKVLKVHRGLWKFEGKATVDDQLACKAELMTIKG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_ACIF5
Sequence: MLTDIVILAAGQGTRMHSALPKVLQPLGGKPMLAHVLATATDLAVRRIHIVVGFGGDAVQAAFPDTQASWWIQAQQLGTGDALKSALPGLTGADRVLVLYGDVPLLTAATLREFLQQTPVTALGLTTASVSEPHGYGRILRDADGQVQGIREHKDCQTDEQAICEINLGMMVLPVQPLAGWLQGLSARNAQGEIYLTDVVAAARADGYVVWPFTLADATEALGVNDPVQLAILERVFQRQQLRALQMQGLRVADPARVDIRGELTCGQDCWVDPNVLFVGEVHLGHRVRVGAGAVLQDARIGDDVEILPYSHIEGAQIGAGARIGPFARIRPGTEIGEAAHIGNYVEVKAAKIGAGSKANHLSYLGDAEIGTGVNVGAGTITCNYDGANKHRTIIGNDVFIGSDSQLVAPVNIGDGATIGAGSTITKEVPPGGLTLSRSPQRTIPHWQRPRRDKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKTS1_HUMAN
Sequence: MASGRPEELWEAVVGAAERFRARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIALAHRAATAARPPAPPPAPQPPSPTPSPPRPTLAREDNEEDEDEPTETETSGEQLGISDNGGLFVMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPPTCSVPPASALPTQQYAKSLPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPRLNTSDFQKLKRKY
What is the function of this protein?
Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals.  mTORC1 is activated in response to growth factors or amino acids.  Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1.  Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases.  Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis.  mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E).  mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation.  Within mTORC1, AKT1S1 negatively regulates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3 proteins.  Inhibits RHEB-GTP-dependent mTORC1 activation.  Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms.  May also play a role in nerve growth factor-mediated neuroprotection.
What are the official names of this protein?
Proline-rich AKT1 substrate 1, 40 kDa proline-rich AKT substrate.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Found in the cytosolic fraction of the brain.
Protein: GLUC_LITCT
Sequence: HSQGTFTSDYSKYLDSRRAQDFVQWLMNSKRSGGISXXHADGTFTSDMSSYLEEKAAKEFVDWLIKGRPKHADGSFTSDFNKALDIKAAQEFLDWIINTPVKE
What is the function of this protein?
Plays a key role in glucose metabolism and homeostasis.  Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.
What are the official names of this protein?
Pro-glucagon.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP6_CITK8
Sequence: MASENMTPQDYIGHHLNNLQLDLRTFSLVDPHNPPATFWTLNIDSMFFSVVLGLLFLLMFRSVAKKATSGVPGKFQTAIELVIGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIGEHIFGLPALRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMGLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPD_BACFR
Sequence: MKQILYKLFEHQYLGRDEARTILQNIAQGKYNDAQVASLITVFLMRNISVEELCGFRDALLEMRVPVDLSEFAPIDIVGTGGDGKNTFNISTAACFTVAGAGFPVVKHGNYGATSVSGASNVMEQHGVKFTDHTDRLRRSMEKCNIAYLHAPLFNPALKAVAPIRKALAVRTFFNMLGPLVNPVIPTYQLLGVYNLPLLRLYTYTYQESATRFAVVHSLDGYDEISLTDEFKVATCGNEKIYTPESLGFNRCRESELDGGNTPEDAARIFDAVMEGTATEAQKNVVIVNAAFAIRVICPEKPIEECIALARESLESGKARETLKKFVELNG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: UBP30_DROME
Sequence: MESEKILMAAGVTVAAVVGAFVFWGPSGSRLRQRRGQIAGLHNFGLTCFLNTLLQAMAACPQFIAWLQLYNNASPDRKSLITSMLNTLEVVNGTHATLRGDPYSPGAVLRALNALGWVIPQEEHDAHELFHVLLTCLEEEAIRPQPLGCLSDALPTDNDDNSSLAGTATPVGGFRSFSSMAAGLGASQRIGDQPNRPSSAMLTDFLNMEYDESTSLQRLVRSEAHTPDSPASVCERDGNDRLGSVLLDAVSPGTPFGFPLVSNPDSLATPMLGGERSSRPRLPQSQQQQDEGLNRRVSSSCRSLERLHRGPGRVSIWSNMMPSQVAHPFQGAMGAQIVCNGCGSKSAVRYDKFDSITLNLPPQRRTGLSLGHLLSEYITSEDLSDVKCDSCNETTTHTKSVTFAKLPACLCIHVARTVWLPTGQVCKRKDYVHFPESLSMAPYSFVQPHLNSQAGTPWGSTMSLYSSSLPMNNGVGGGEGFGTMFPKNLYRLLAVVVHSGEANSGHFVTYRRGSLRNAHRWYYTSDTIVREVSIDEVLSVPAYLLFYDRGQQRQLNLR
What is the function of this protein?
Deubiquitinating enzyme that acts as a key inhibitor of mitophagy by counteracting the action of parkin (park).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 30 homolog, dUSP30, Deubiquitinating enzyme 30 homolog, Ubiquitin thioesterase 30 homolog, Ubiquitin-specific-processing protease 30 homolog, Ub-specific protease 30 homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: BIOB_CAMJD
Sequence: MQIMLCAISNIASGNCSEDCKYCTQSAHVRTDIQKYRRKELSQIVLEAKMAKKNEALGFCLVTAGLGLDDEKLEYVCEAAKAVQKEVPNLLLIACNGMASVEQLKELKKAGIFSYNHNLETSKEFFPQICTTHTWESRFQTNLNAKEAGLMLCCGGIYGMGESEENRLSFRKSLQELQPFSTPINFFIANENLKLQTPRLSADEALKIVRDTKEALPQSVVMVAGGREVVLQERQYEIFQAGAGAIVIGDYLTTKGEEPSQDIIKLKEMGFTFASECH
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: MALT_KLEP3
Sequence: MLIPSKLSRPVRLEHTVVRERLLAKLSGANNYRLVLITSPAGYGKTTLISQWAAGKNDLGWFSLDEGDNQQERFASYLIAAIQQATGNHCAASEAMVQKRQYASLSSLFAQLFIELADWQRPLYLVIDDYHLINNPVIHDAMRFFLRHQPENMTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLTSPIEADDSSRLCDDVAGWATALQLIALSARQNNSSAQHSARRLAGINASHLSDYLVDEVLDNVDARTRNFLLKSSLLRSMNDALIVRVTGEENGQMQLEEIERQGLFLQRMDDSGEWFRYHPLFGSFLRQRCQWELAVELPEIHRAAAESWMAQGFPSEAIHHALAAGDAKMLRDILLNHAWGMFNHSELGLLEQSLSALPWSNLLENPRLILLQAWLMQSQHRYSEVNTLLARAEQEMSVEMDTAMHGDFNALRAQVAINDGDQDEAERLSMVALEELPLANYYSRIVATSVHGEVLHCKGKLTKSLAVMQQTEQMARRHDVWHYALWSIIQQSEILFAQGFLQAAWESQEKAFQLVREQHLEQLPMHEFLLRIRSQLLWAWARLDEAEACARQGMDVLSTYQPQQQLQCLALMVQCSLARGDLDNARSHLNRLENLLGNGHYHSDWVSNADKVRVIYWQMTGDKTAAANWLRQTPKPEFANNHFLQSQWRNIARAQILLGDFEPAEMVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSEAQKALLEALTLANRTGFINHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILRDINQHHRHKFAHFDEGFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: RK33_ILLOL
Sequence: MAAGKDVRVTVILECTSCAKNGANKKSPGVSRYITEKNRHNTPGRLELIKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NPP1_YEAST
Sequence: MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGFHSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGDIPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTSFTNLVIVSDHGMSDIVVPSNVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDEDKYTVYVNGNFPKEWNFNDGKNHHMASIWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYDNNAIDMRSVFIGMGPYFPQGYIEPFQNTEIYNLLCDICGVAEKDRNSNDGTGMLMNQLREPQSSEEVEIEDDFDYLVSKFGEFSTYNIIWGGYPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT
What is the function of this protein?
Mediates extracellular nucleotide derived phosphate hydrolysis along with NPP2 and PHO5.
What are the official names of this protein?
Ectonucleotide pyrophosphatase/phosphodiesterase 1, E-NPP 1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: AOX1_SOYBN
Sequence: MMMMMSRSGANRVANTAMFVAKGLSGEVGGLRALYGGGVRSESTLALSEKEKIEKKVGLSSAGGNKEEKVIVSYWGIQPSKITKKDGTEWKWNCFSPWGTYKADLSIDLEKHMPPTTFLDKMAFWTVKVLRYPTDVFFQRRYGCRAMMLETVAAVPGMVAGMLLHCKSLRRFEHSGGWFKALLEEAENERMHLMTFMEVAKPKWYERALVITVQGVFFNAYFLGYLLSPKFAHRMFGYLEEEAIHSYTEFLKELDKGNIENVPAPAIAIDYWQLPPGSTLRDVVMVVRADEAHHRDVNHFASDIHYQGRELREAAAPIGYH
What is the function of this protein?
Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation.  May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.
What are the official names of this protein?
Ubiquinol oxidase 1, mitochondrial, Alternative oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the alternative oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Note=Mitochondrial, possibly in the inner surface of the inner mitochondrial membrane.
Protein: Y469_STRPG
Sequence: MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYIDYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFSKAYITIWYKRYLELKNR
What are the official names of this protein?
UPF0374 protein SpyM50469.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: RSMD_ECOLI
Sequence: MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLFNWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATLIEMDRAVSQQLIKNLATLKAGNARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADEALIYVESEVENGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDAD
What is the function of this protein?
Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase D, 16S rRNA m2G966 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmD family.
Protein: IF3_XYLFA
Sequence: MGDCNISTSDNKQNRKNHEIRVPRVRVIGSDGEMVGVLSRDEALAMAEKEGLDLVEIQPQADPPVCKVMNFGKFKFEQQKKANEAKKKTKQVEIKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKINIRFRGREMSHQELGRQMATRIEMDLGDDVVIESRPRLEGRQMVMMVAPRKKS
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSL2_HUMAN
Sequence: MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
What is the function of this protein?
Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure.  Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A.  This activity is greatly enhanced by heterodimerization with MSL1.  H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.
What are the official names of this protein?
E3 ubiquitin-protein ligase MSL2, E3 ubiquitin-protein transferase MSL2, Male-specific lethal 2-like 1, MSL2-like 1, Male-specific lethal-2 homolog, MSL-2, Male-specific lethal-2 homolog 1, RING finger protein 184.
What is the protein family that this protein belongs to?
Belongs to the MSL2 family.