PharMolix/UniProtQA huggingface dataset:
Protein: RL5_ALISL
Sequence: MAKLHDYYKSSVVAELTKEFSYSSVMQVPRVEKITLNMGVGEAINDKKLLENAAADMAIISGQKPLITKARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVSIALPRVRDFRGVSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTSANTDAEGRALLAAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: FADJ_YERPP
Sequence: MSKENIVTRENTAVSENAVSEPTVNNDVGASATNSVTHPAFTLNVRPDNIGIITIDVVGDKVNTLKAEFADQIATILQQAHALPKLQGLVIVSGKPDSFIAGADITMIAACRTAHDARVLAQKGQSILAQIAAFPVPVVAAIHGACLGGGLELALACHSRICSLDDKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSKALDMILTGKQIRPRQALKMGLVDDVVPRDILLDVAIQRAKAGWLNRRALPWQERLLSGPLGKALLFRIVRKKTLAKTRGHYPAAERIIDVVRKGLDQGGPSGYEAEARAFGELAMSPQSAALRSLFFATTSLKKETGSAATARAIHRVGVLGGGLMGGGIANVTATRAGLPVRIKDINPQGINQALKYTWDALGKRVRSKRMRPTEQQRQMMLISGSTDYRGFERVDIVVEAVFEDLSLKQQMVADIERFGAAHTIFASNTSSLPISQIAALAQRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATTVALARKQGKTAIVVADRAGFYVNRILAPYINEAARCLLDGEPIESVDNALVDFGFPVGPMMLLDEVGIDVATKIMPILVEQLGPRFAAPPSFDVILKDGRKGRKNGRGFYLYSNPTKNSSPTKNGNSPAKRNSFKWRKNKVKPVDASIYTLLGVTPKAHLGAGVITQRCTMLMLNEAVRCLDESIIRNPRDGDIGAVFGIGFPPFLGGPFRYLDSLGADKVVQALRLLVQQYGERFEPCQRLVTMAEQQQQFYPVDANIDEVTDVAS
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL_YERE8
Sequence: MKQVVYVASPDSQQIHVWQLGSTGELTLLQTVEVPGQVQPMTINPNQRHLYVGVRPDFGIVSYNIADDGTLTAAGMAPLPGSPTHIGTDLQGRFLFSASYSFNCVSISPIDEHGVVQTPIQQLNDLPAPHSANIDPTNQILLVPCLKEDKVRLFDLSAEGKLTPHAQSDVTVAAGAGPRHMAFHPNQQVAYCVNELNSSVDVYQISNNGQEYKIIQTLDAMPADFTDTCWAADIHITPNGRHLYISDRTASLLGIFSVSEDGREIALVGHHQTEAQPRGFNIDHNGQFLISSGQKSDHIEVYRIDQISGELTTLKRYPVGKGPMWVSILAPRA
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: PVK1_DERIN
Sequence: GASGLIPVMRN
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, DerIn-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: REC8_CAEEL
Sequence: MVVSAEVIRKDAVFHVAWILGTGDSKKLSRREILDQNLPELCHSIIEMVPERHRGSATKTGLYLLSLLTYGTVLIHQVQVDFLKRDVEKLKELMKKKSFILLMAERFDRNQELQRKEDKFARLRSKPIMCVEELDRVDLAHLQAIGDELGINGNPGDFIMMDALPNMNQWIDNNSELNAIYGCVEPYLREKEITMHSTFVEGNGSNEHNKERRNDAVIADFSQLLFPEIPEITLGEKFPIDVDSRKRSAILQEEQEEALQLPKEASEIVQEEPTKFVSIALLPSETVEQPAPQEPIQEPIQPIIEEPAPQLELPQPELPPQLDAIDLVTIPASQQDMVVEYLQLINDLPDDENSRLPPLPKDLELFEDVILPPPAKKSKVEEEEDALERARRRPSSRPVTPINQTDLTDLHSTVRPEDPSFAIDSQIHDVLPQRKKSKRNLPIIHSDDLEIDEAVQKVLQADYSSLVRKKEDVIAKIPPKTDAVAVLMNLPEPVFSIGYRLPPEVRDMFKACYNQAVGSPVSDDEEDEDEEEEEEYKYAKVCLLSPNRIVEDTLLLEEQPRQPEEFPSTDNINPPRQLQENPVFENLEYEAPPHPIRTARTPTPIKDLKYSVISLFPTPEKRRETSIIAELNLDPIPVEEIDPLLTMRTEEELENVRRRQKSSLGVQFMRTDDLEEDTRRNRLFEDEERTRDAREDELFFYSSGSLLPNNRLNIHKELLNEAEARYPEWVNFNEFTADHDRKKAATAFEGLLLSLKNMKVEAKQEDPYFPILVRHISHEEM
What is the function of this protein?
Plays a role in meiotic chromosome cohesion and segregation (PubMed:11390355, PubMed:25171895).  Necessary for sister chromatid co-orientation and sister chromatid cohension until meiosis II (PubMed:19574299).  May also be required for repair of programmed meiotic double stranded breaks (PubMed:11390355).  During spermatogenesis, likely involved in spermatocyte centriole cohesion, thus preventing their separation during the second meiotic division (PubMed:23401519).
What are the official names of this protein?
Meiotic recombination protein rec-8, Cohesin rec-8.
What is the protein family that this protein belongs to?
Belongs to the rad21 family. Highly divergent.
What are the subcellular locations of this protein?
Chromosome. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Colocalizes with smc-1 along synapsed chromosomes during meiotic pachytene and diakinesis (PubMed:12827206). Loaded onto chromosomes upon entry into meiosis (PubMed:21856158). Localizes to chromosomes until meiotic anaphase II and to microtubules throughout meiotic divisions (PubMed:23401519).
Protein: C2AIL_BOVIN
Sequence: MVGGEAAAAVEELISGVRRATDFAEQFRSYSESEKQWKARMEFILRHLPDYRDPPDGGGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLPQFTTRSELMKKHQS
What are the official names of this protein?
CDKN2AIP N-terminal-like protein, CDKN2A-interacting protein N-terminal-like protein.
What is the protein family that this protein belongs to?
Belongs to the CARF family.
Protein: CTL1L_DROME
Sequence: MGCAESKDGEGEAQNNRPKYRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNTCGVKYNEKFQGFPLSGMNTLDKPELFYFDVKELKKSLKICVKSCPAKTMTKGSELLEYYSQTGTQLCKYDYNMQQLTTAGNDAKTFNFLGPCPSFPVHESSPVLHRCVPKGTGEKVQNYYDMLNNWDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVASVALTVALWYAYYNIRNKSGVNTQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQPLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVAFWYFQKPTSTPTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGKVVVAALSGLIGIVLLKDKPGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKTLNGRSGRWAQSNLAKLVGEEPLQPGEEPPIEVVQMMPINKQPFSITRLPQSDPEVAPMSAD
What are the official names of this protein?
Choline transporter-like 1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACTC_BOVIN
Sequence: MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, alpha cardiac muscle 1, Alpha-cardiac actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LCL3_ZYGRC
Sequence: MGDNRNLPVTQPNSINFNVVILSIFFSGSFIGAWAFFNRFLKQYTKATEIPQNVFRKRWLFGKVTAVGDGDNFHFFHAPGGLIAGWGWLRPLPELNKSDPPISSSKVGSSVPIHRRIFDSIFGRNKTRTAYSNYFLGLPVPYKNKRNLPTISIRICGVDAPERAHFGNPAQPFSEEALIWLRHTLIGKCVWIKPLAVDQYNRCVAKVEYWTWTGWKNVSLEMVKQGLAVVYESKTSAEFDGEEDKYRFHEMAAKARRRGIWSQKQFETPGEYKRRI
What are the official names of this protein?
Probable endonuclease LCL3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: SSN8_KLULA
Sequence: MSASYWDSSQRHKWKYTRESLAKEKQKLWLLECQLFPQGLNVTIHDSKANKQVTTNIPVTQRDLHYDRDYNLRIYCYFLIMKLGRRLNIRQCALVTAHVYLSRFLLRASVREVNLYLLITTCIYLACKVEECPQHIRTLVNEARSLWPEFIPPDVTKVTEFEFYLIEELQSYLIVHHPYRSLEQIEKALSSEKYNYKLSDDELQKIWSLINDSYTTDVHLLYSPHVIAISCLFAVSCIIHKPEDSTKRANINMFIAETQVNLEQVMFILQELISLYDHWDKYNELRIRALLHELYLRQQTPAIQ
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
RNA polymerase II holoenzyme cyclin-like subunit.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDH_PASMU
Sequence: MKVAVLGAAGGIGQALALLLKLQLPAGSELSLYDIAPVTPGVAADVSHIPTAVKVQGFAGEDPTPALQGADVVLISAGVARKPGMDRSDLFNINAGIVRNLIEKVAQVCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKRKLFGVTTLDIIRSETFVSELKNLEPARTTVPVIGGHSGVTILPLLSQVQYAEWNDAEIAPLTKRIQNAGTEVVEAKAGGGSATLSMAQAAARFALSLVKGLNGENVVECTYVEGDGKYARFFAQPVRLGKEGVEEILPLGSLSAFEQHALDAMLETLRADIELGEKFVNQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: PA2B_TRIPE
Sequence: MRTLWIMAVLLVGVEGSLLEFGRMIKEETGKNPLFSYISYGCYCGWGGQGQPKDATDRCCFVHDCCYGKLWSCSPKTDIYFYYRKNGAIVCARGTWCEKQICECDKAAAICFRENLGTYKAEYESYGKSRCTEKSLKC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that impairs hemostasis.  It weakly inhibits ADP-induced platelet aggregation when tested on platelet rich plasma from human and rabbit blood (15-25% of inhibition at 5-10 ug of enzyme), and dose-dependently inhibits blood coagulation, possibly by inhibiting thrombin activation.  Also induces local edema a few hours after injection in the hind foot.  Exhibits high hydrolytic activities toward L-dipalmitoyl phosphatidylcholine.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 Tpu-G6D49, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMU_SHEB2
Sequence: MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHKVGSDAIQLVYGYGADKLQASLGEQQLNWVLQAEQLGTGHAVAQASPHIADNDTVLILYGDVPLIQQSTLEALLAARPENGVAILTVNLANPMGYGRIVRTPCEGQEQGKVVGIIEQKDATAEQLLINEINTGIMAVPGKQLKAWLSRLSNNNAQGEYYLTDIIAMAHDDGVAIDTAQPQSAIEVEGANNRVQLAQLERAYQAREAEKLMLAGANLRDPSRIDIRGEVTVGMDVMIDINVIFEGKVTLGNNVTIGAGAILIDCEIADNAEIKPYSIIEGAKLGVAASAGPFARLRPGAELKQDAHIGNFVEVKKAVIGVGSKAGHLAYLGDAVIGDGVNIGAGTITCNYDGANKHLTVIEDNVFVGSDTQLVAPVTIGKGATLGAGSTITRDVGENELVITRVKQKHLTGWQRPVKIKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B2CL2_CANLF
Sequence: MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
What is the function of this protein?
Promotes cell survival.  Blocks dexamethasone-induced apoptosis.  Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity).
What are the official names of this protein?
Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein. Note=Loosely associated with the mitochondrial membrane in healthy cells. During apoptosis, tightly bound to the membrane (By similarity).
Protein: SCDA_STAAW
Sequence: MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein ScdA.
What is the protein family that this protein belongs to?
Belongs to the RIC family. ScdA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAPA_SPHXN
Sequence: MTSTQRLWSGALPLLTALIVSIAATASLAGPRARDLGVPFEGTPGALNAITDVAGVEVGHTTVISGDGAMVIGKGPYRTGVTIIHPLGKTSLDGVAAGRAVINGTGEWTGMHLVDEVGQFLGPIALTGTGNVGLVHQSMMDWSVGKVPEEALFSRLLPVVAETLDNRLNDVFGHGLTRDHVFAALDGAKGGPVAEGNVGGGTGMIAYTFKGGIGTSSRVVSAGDTRYTVGVLVQANHGDRNDLRIAGVQIGKEIKGAWPEVNGIVAAGPDAGKPQDKNSLLIVIATDAPLMPHQLERMARRAALGVGRNGSTAGALSGEFALAFSTSHVIPLGGKPRLPAIINDTDSETMNALFRGVVQATEEALVNQLVASETMTGANNAKVYGIPHDQLARIMKARFPRR
What is the function of this protein?
Beta-aminopeptidase that can cleave synthetic beta-peptides which consist of backbone-elongated beta-amino acid residues that are not processed by common proteolytic enzymes.  Can cleave the beta-peptides beta-homoVal-beta-homoAla-beta-homoLeu and beta-homoAla-beta-homoLeu.  Requires a beta-amino acid at the N-terminus of peptide substrates and cleaves the peptide bond between the N-terminal beta-amino acid and the amino acid at the second position of tripeptidic substrates of the general structure H-betahXaa-Ile-betahTyr-OH according to the following preferences with regard to the side chain of the N-terminal beta-amino acid: aliphatic and aromatic > OH-containing > hydrogen, basic and polar.
What are the official names of this protein?
Beta-peptidyl aminopeptidase BapA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S58 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RNC_ECOHS
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_BACSU
Sequence: MNIHEYQGKEVLRKYGVSVPEGKVAFTAEEAVESAKSLSSSVYVVKAQIHAGGRGKAGGVKIAKSLDEVKAYAEELLGKTLVTHQTGPDGQVIKRLLIEEGCDIKKEYYIGLVLDRATSRIVLMASEEGGTEIEEVAEKTPEKIKKAVIDPAVGLQGYQAREIAFAINIPKELVGKAAKFMLGLYKAFVEKDCSIAEINPLVVTGDGNVMALDAKLNFDSNALYRQKDIMEYRDLDEEDPKEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTEAFKIILSDQNVKGIFVNIFGGIMKCDVIAEGVVEATRQVGLTLPLVVRLEGTNVDLGKKILSESGLNITSAESMADGAQKIVSLV
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MBHS_SHIFL
Sequence: MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAWALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAEEVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTCASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVDRMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACSSTRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGVVAAAVGVHAVASSVDQRRRHNQQPTETEHQPGNEDKQA
What is the function of this protein?
This is one of three S. flexneri hydrogenases synthesized in response to different physiological conditions.  HYD1 is believed to have a role in hydrogen cycling during fermentative growth (By similarity).
What are the official names of this protein?
Hydrogenase-1 small chain, HYD1, Membrane-bound hydrogenase 1 small subunit, NiFe hydrogenase.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein; Periplasmic side.
Protein: FOLD_SHESM
Sequence: MTAQIIDGKAIAQSIRTQLREKVTARKEAGQRVPGLAVILVGADPASQVYVGSKRKACEEVGFISRSYDLDTSYTEEALLALIDELNDDPTIDGILVQLPLPAHIEDSKVIERIRPDKDVDGFHPYNVGRLAQRIPVLRSCTPMGIMTLIKSTGVDTYGLDAVVVGASNIVGRPMTLELLLAGCTTTTCHRFTKNLEQKIRQADLVVVAVGKPGFIPGEWIKPGAIVIDVGINRLENGTLVGDVQYDVAAQNASFITPVPGGVGPMTIASLLENTLYAAEQYHD
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RNH_BRASB
Sequence: MSELPTVSIYTDGACSGNPGPGGWGAILRFGDKEKELKGGEPHTTNNRMELMAAISALEALKKSCQVELYTDSQYVRQGITGWIHGWKRNGWKTADKKPVKNAELWQRLDAALKPHKVNWHWVKGHAGHAENERADQLARDGVAMARLQKNVRG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX3_ORYSI
Sequence: MIESQRHSYHLVDPSPWPISGSLGALATTVGGVMYMHSFQGGATLLSLGLIFLLYTMFVWWRDVLRESTLEGHHTKAVQLGPRYGSILFIVSEVMFLFAFFWASSHSSLAPTVEIGGIWPPKGIGVLDPWEIPLLNTPILPSSGAAVTWAHHAILAGKEKRAVYALVATVLLALVSTGFQGMEYYQAPSTISDSIYGSTFFLATGFHGFHVIIGTLFLIVCGIRQYLGHLTKKHHVGFEAAAWYWHFVDVVRLFPFVSIYWWGGI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NINJA_TOBAC
Sequence: MDENGLDLSLGLPCGGGAASEKSKSGSSSDSKVEEVDRDGKVINDFKNFLDGGTSSQKHDSGVGSQRSDSTKHEGNLLSSINVDVDASKKLNSGGFWVQNDSRPVEVEEDRRADVGDKRKNLFRESSQQKKQEREGHHADTHDKTRTSHISITTDEGSTAENEDVADSETVGSTSRQILQHDESSKRFVGSSGLAEVHKELRSVPASSGVELIGQRRFTISSEKDVKFGNIPYTIPFQGQSINIMNLPYSMPLNSNTVSTTSTTSYPVPGVMQLMATTCVDRPPSHPVIPAYLPLMFGYSSVQLPTLDNDNLHGVASHLLQLHPSHGRGPLGSDKQKDGPNISQAAASSIPHKSSDSVQYDGRAMEHVKGNGRQHKAEETSNSRGEENVKGSNISFRAKDPPDQPRAEAVPSEFSTIRPGLAADLKFGGSGSYPNLPWVSTTGPGPNGRTISGVTYRYSSTQIRIVCACHGSHMSPDDFVRHASVEQTSQEPGTGVSSFPSSNPAASAQS
What are the official names of this protein?
Ninja-family protein mc410.
What is the protein family that this protein belongs to?
Belongs to the Ninja family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NOP10_THEAC
Sequence: MKSLIRKCPRCHAYTMEEKCPKCGSDTYIAVPPRYSPVDRFRKYRIEELRGEIDGENSGDQI
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: ELAP_ECOLX
Sequence: MKNITFIFFILLASPLYANGDRLYRADSRPPDEIKRSGGLMPRGHNEYFDRGTQMNINLYDHARGTQTGFVRYDDGYVSTSLSLRSAHLAGQSILSGYSTYYIYVIATAPNMFNVNDVLGVYSPHPYEQEVSALGGIPYSQIYGWYRVNFGVIDERLHRNREYRDRYYRNLNIAPAEDGYRLAGFPPDHQAWREEPWIHHAPQGCGNSSRTITGDTCNEETQNLSTIYLREYQSKVKRQIFSDYQSEVDIYNRIRDEL
What is the function of this protein?
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
What are the official names of this protein?
Heat-labile enterotoxin A chain, LT-A, porcine, LTP-A.
What is the protein family that this protein belongs to?
Belongs to the enterotoxin A family.
Protein: PSBI_LEMMI
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.