PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_STRPF
Sequence: MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVGRYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKFVYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIVWLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQHNGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIADGPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: OBG_UREU1
Sequence: MAFIDKCKIVLIAGNGGDGIVSWRRETHVPEGGPAGGNGGNGGSIWFVGNHNETSLEFLKYKKIIRAKHGEKGDIKNQHGANAEDVFINVPLGTVVYDAITNEILADINIDQQKYLVAQGGLGGHGNTHFKSAFNKAPNLYELGELGENIEVVLELKTIADIGIIGLPNAGKSTLISSFTNAKPKTANYMFTTLNPVLGTIYRDQNRIIFADIPGLIEGAHTGVGLGHDFLKHIERCFLLIHLISLDPNDNSDIISAYETIVNELKQYKQSLVNKPIVLVANKIDQIGALENLQILKEHLKDNQYIKVISALTNLHVDAMLDDVIKIYFDQKKIYEQRLKEHLPVDQILKWASDTPKNKELDKTIKIVKVDDHFFEVFGEYLKYWVHRIPLKTQDNLIRFNQKLQSINFNQQLLQAGAIAGDSIKIYDITLEFEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_ECOHS
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RRF2M_PICGU
Sequence: MFSINARTKVPIWVPFIARKGFSMSTRQLAEPKLNQVSSLNTRNIGIIAHIDAGKTTTTERMLFYSGKTTTMGDVDQGDTVTDYLPSERSRGITIQSAAITIPWNNNKINIIDTPGHADFTFEVIRSLRVLDGCVTILDAVAGVEAQTEKVWKQAQALKIPRIAFVNKMDRPGAGFSRTVKEVVQKLQTKVVLCNIPYFEMSKDDAVFVGVIDILHNKILKWNIDEDPNGRDITVIDLQEAKESHQEAYMEALKCRESMVETLGGIEETVVDAFLECDEDYMKIPSSILKSAIRKACISNQVTPVFCGSAFRKIAVQPLLDGVVDYLPSPLQTPVPEITASTSKVSKKQKQKKNSKVSSVPIEMNPKKGLIVNKNPQLTVALAFKVMTHATRGVMTFFRVYSGSLTSNTTVVNTRTGKKLHLNKVLLMHGDTPEPVSQISSGNIGVITGTENDVITGDTLVSHGPVKRNFTDLETSIKLLPIEIPPPLFNSSIEPLTAGDARYMNECINTLIREDPSLNVNVDEELGQTILSGMGELHLEIVRDRLINDMKAKIRLRNVAVSFKETVSKPSLEVVKASKNDGLVKVEVSLEAIDGPAEESTHADENGSVLLETDNNVVKLPPEAAASHINESLSERRWKSEHSLEELNDIILQGITTGLQLGGPILGLPLHSVVVRVIHWDFPVEGKEVSASMLLDASRQVVREALSKLPESSFCILEPIMSTRVYVDSGSMGEVVHDLSHRCSAHITSIEDESENMDSNAWANEEAENLYLPQDYTMKSGKNAVNFTNKKVVVAETPLRDMVGYLSKLRSITQGRGVFDMTYLGMRRAIRPVLLDS
What is the function of this protein?
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.  Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
What are the official names of this protein?
Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GATB_BLAGS
Sequence: MIRQCLSRRGAYSRYRLAARGVELAEPFHHQSSRPQGRRNWSSSPRCSLDIRTDTPRSRSEYVPLRKQLKEEAKAKRAAKRKGSAPPAKHDDWELTVGIEIHAQLDTDAKLFSRASAAIDDIPNSNVALFDIALPGSQPLFQPSTLIPALRAALAMNCDIQRVSRFDRKHYFYQDQPAGYQITQYYEPYAKNGSIWLQEHDGIAREDGEGVQIGIKQIQMEQDTAKSQELPSSTYLLDFNRVSRPLIEIITLPQIHSPATAAACVRKIQAILQSVGAVTTGMEMGGLRADVNVSVRKRSEGAGDHEYHGIVGLGQRTEIKNLSSFKAVEDAIIAERDRQIAVLEAGGTIEGETRGWTLGSTETRKLRGKEGEVDYRYMPDPDLGPVVIGEDVICDLQMKMPLLPDALFQMLVRNPKYKLSTADAKTMIELDDGQRLEYYQDVVDILIGLQTDLSADFSGGKAVGNWVLHELGGLLTKSSLPWDSGRVPAQSLAEIIDLLSRKEITSSSAKSLLAMVFDGDKRSVAQIVEDENLRFQSLSRGEYIALAEEVMRQNPKMVSEIREKGQLGKIGWFVGQIKRIGDANRVEAQKAEEILRELILKKNS
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ISPH_CHLFF
Sequence: MRRVILSNPRGFCAGVVRAIQVVEAALEKWGAPIYVKHEIVHNRHVVDDLRRRGAIFIENLSDIPCGGKVIYSAHGIPPEVREEAKNRNLFDIDATCVLVTKIHSAVKLYASKGYQIILIGKKKHVEVIGIYGEAPDSVTVVEKVEDVENLPFGIDTPLFFVTQTTLSLDDVAEITQALKVRYPNVITLPSSSVCYATQNRQEALRSVLPRVNFVYVVGDVQSSNSNRLREVAERRNIPARLVNSPDHISDEILNYSGDIAITAGASTPENIVQLCISRLKELIPDLQVEEDIFAIEDVVFQPPKELRN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PDXT_STRP4
Sequence: MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSGLILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGTMDMVVERNAXGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SNX31_HUMAN
Sequence: MKMHFCIPVSQQRSDALGGRYVLYSVHLDGFLFCRVRYSQLHGWNEQLRRVFGNCLPPFPPKYYLAMTTAMADERRDQLEQYLQNVTMDPNVLRSDVFVEFLKLAQLNTFDIATKKAYLDIFLPNEQSIRIEIITSDTAERVLEVVSHKIGLCRELLGYFGLFLIRFGKEGKLSVVKKLADFELPYVSLGSSEVENCKVGLRKWYMAPSLDSVLMDCRVAVDLLYMQAIQDIEKGWAKPTQAQRQKLEAFQKEDSQTKFLELAREVRHYGYLQLDPCTCDYPESGSGAVLSVGNNEISCCITLPDSQTQDIVFQMSRVKCWQVTFLGTLLDTDGPQRTLNQNLELRFQYSEDSCWQWFVIYTKQAFLLSSCLKKMISEKMVKLAAENTEMQIEVPEQSKSKKYHIQQSQQKDYSSFLSRKSKIKIAKDDCVFGNIKEEDL
What is the function of this protein?
May be involved in protein trafficking.
What are the official names of this protein?
Sorting nexin-31.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
Protein: SYGA_STRP4
Sequence: MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEKLGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAEVTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFDKFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVAKTFVAERKRLGYPLLDEETRAKLLAEDAE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_CLOP1
Sequence: MINKDYKKLYLVTDYRIPFNELLEKTKEALIGGVSIVQYRAKNKKTKEMCKEAKELKKLCDEFGALFLVNDRIDVALAVKANGVHIGQDDMEVFIAREIMPKDAVIGVTVHNKEEALKAIKEGADNLGVGALFSTNSKDDATLMTLETLREIKSVSNIPLYGIGGITPYNLNKDILENLDGVAVISALLNSDNIREKSKEFLNILSK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: ADRB3_SHEEP
Sequence: MAPWPPGNSSLTPWPDIPTLAPNTANASGLPGVPWAVALAGALLALAVLATVGGNLLVIVAIARTPRLQTMTNVFVTSLATADLVVGLLVVPPGATLALTGHWPLGVTGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRRARAAVVLVWVVSAAVSFAPIMSKWWRVGADAEAQRCHSNPRCCTFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRRELGRFPPEESPPAPSRSGSPGPAGPYASPAGVPSYGRRPARLLPLREHRALRTLGLIMGTFTLCWLPFFVVNVVRALGGPSLVSGPTFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLLCRCPPEEHLAAASPPRAPSGAPTVLTSPAGPRQPSPLDGASCGLS
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  Beta-3 is involved in the regulation of lipolysis and thermogenesis.
What are the official names of this protein?
Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMM_PSEPF
Sequence: MSATPEKADDLIVVGKIFSVHGVRGEVKVFSFTDPIENLLGYRNWTLRREGVVKQVELVSGRSTQKDLVVKLKGLDDRDEARLLSGYEICIPRSLLPDLTADEYYWYQLEGLSVINQDEQLFGKVDHLLETGANDVLVVKPCVGSLDDRERLLPYTEQCVLAIDLEAGVMRVEWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPB3_ASFK5
Sequence: MEKIFQNVDIKPLLIDFSNPFIKNAAKKLFQLEEQLPLVPVNVMMDFKGINRATVHGLSRVLQDEIPNYMLDIKPGGYKIEDSTDLFMTEQFVRNRINFIPIYAENETLVFALRSLNNSCEVKTIYSRDLIQVAGPKLKYPIFNPTFEIGFLQPGKSLIIEDIYIKKGIGRKHAAFNLAVKTHFSHLDIEQYPTDKKEYMALSGYKQSSMTSDPRHHRLGLCFPAVPLPRINQVVRTYLKNACRVIIGRIQNIQKIYENFEEPQPELVLFSMDEEKTKAIITIKDETHTIGNLLKTCIYEMIPDISFVGYQCIPHKQEMVLTIIHKASQEDLITLLEKSIQNIIQIFQTLEKNIDERIA
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB3-11 homolog, RPB3-11 homolog.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: RL18_CORDI
Sequence: MSNTENNNAKRLPVGKDISTRRRIARARRHDRIRKNLRGTAETPRLVVHRSSRHMHVQVIDDIAGRTLAAASTLEAEVRALEGDKKAKGAKVGQLIAERAQAAGITAIVFDRGGYKYHGRIAALADAAREGGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: YEBY_ECOLI
Sequence: MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEVMLTCRPGNALYVINPSTLVQYPLNDIAQKEVASGKTNAQPISVIQIDDPNNPGEKMSLAPFIERAEKLC
What are the official names of this protein?
Uncharacterized protein YebY.
Protein: ARAB_STAAB
Sequence: MSYSIGIDYGTASGRVFLINTTNGQVVSKFVKPYTHGVIESELNGLKIPHTYALQNSNDYLEIMEEGISYIVRESKIDPVNIVGIGIDFTSSTIIFTDENINPVHNLKQFKNNPHAYVKLWKHHGAYKEAEKLYQTAIENNNKWLGHYGYNVSSEWMIPKIMEVMNRAPEIMEKTAYIMEAGDWIVNKLTNKNVRSNCGLGFKAFWEEETGFHYDLFDKIDPKLSKVIQDKVSAPVVNIGEAVGKLDDKMAQKLGLSKETMVSPFIIDAHASLLGIGSEKDKEMTMVLGTSTCHLMLNEKQHQVPGISGSVKGAIIPELFAYEAGQSAVGDLFEYVAKQAPKSYVDEAANRNMTVFELMNEKIKHQMPGESGLIALDWHNGNRSVLSDSNLTGCIFGLTLQTKHEDIYRAYLEATAFGTKMIMQQYQDWHMEVEKVFACGGIPKKNAVMMDIYANVLNKKLIVMDSEYAPAIGAAILGAVSGGAHNSINDAVDAMKEPILYEINPEAEKVQRYETLFKAYKALHDIHGYKKANIMKDIQSLRVEG
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: RECO_CHESB
Sequence: MEWHDEGIVLGTRRHGESSVILEAITAAHGRHLGLVRGGRSKRMQPVLQPGNRVDLTWRARLDEHLGLFQVEPLELNAARLLNSAVAIYGIQLLAAHLRLLPERDPHPGLFEALGVIAAHLDEPETAGVLVARFELAVLDALGFGLDLARCAVTGSREDLAYVSPKTGRAVTREAGAPWADKLLPLPTFLTAGNEALYDRAILSQAFALTGFFFARHVYEPRGLTEPEARAGFLAAVMRNLPEGESAP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TSAD_MAGMM
Sequence: MLRVLGIESSCDETAAAVVEGAEHGHPHGVVVRSNVVWSQLEVHALYGGVVPELASRAHIRHIQPVIEQALAEAGVRPQQLDAIAVTVAPGLVGALLVGVAAAQGLAVALDKPLVPVHHMEGHLMSPFLMAGVVPAMEFPFVALLVSGGHTLLLHARDFGDYQLLGQTRDDAVGEAFDKGARMLGLGYPGGPEVAALAQSGDRQAVAFPRVLLDRSQFDFSFSGLKTALRTHLLKFPPESGGPSLADVAASYQEAIVDTLVIKSLSACRHVGVSRLVIAGGVGANRRLREKLAKQALKQGVQLYAPPIHLCTDNGAMIASAGVCRLARGDQARGVVNAVPRLPIHELEKIYGR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMD3_DANRE
Sequence: MEYMQAPPSSSHGNILCCTCGVPIPPNPANMCVSCLRTQVDISEGIPKQVTIHFCRQCERYLQPPGSWVQCALESRELLALCLKKLKASMSKVRLIDAGFLWTEPHSKRIKIKLTIQKEVMNGAILQQVFTVEFVVQGQMCEDCHRVEAKDFWKAVVQVRQKTVHKKTFYYLEQLILKHKLHQNTVRIKEIHEGIDFYYATKQHAQKMVDFLQCTVPCRSKASQRLISHDVHSNTYNYKSTFSVEIVPVCKDNVVCLSPRLAQSLGNMGQVCVCVRVTSSIHLIDPNTLQIAEVDGSTFWRHPFNSLCSPRQLEEFIIMDIDIIRDQRLGAGAGLKSNKHTLAEVWVQKTSEMDSSHQYHCRTFMGHLLNIGDLVLGFDFANANINDEFLNKMNPQHVPDVVLIKKSYDRMKRARKRVWKLKEMDREKDAADTDDERQYTEFLEDLEEDEMLRKNINIFRDASKIPVEESDTDDDGAPRISLAEMLEDLSLSDATGGEGADMMTD
What is the function of this protein?
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
What are the official names of this protein?
60S ribosomal export protein NMD3.
What is the protein family that this protein belongs to?
Belongs to the NMD3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.
Protein: DAPEL_BACCN
Sequence: MTISKFVQIRRDLHQIPELGFQEWKTQQYILNYIETLPNEHIEVKTWKTGVIVKVKGKNPVKTIGYRADMDGLPIVEETGYEFASTHEGMMHACGHDFHTTIGLGLLTATVNDRIDDDLVFLFQPAEEGPGGALPMLESEELKEWKPNMILGLHIAPEYPVGTIATKEGLLFANTSELYIDLKGKGGHAAYPHMANDMIVAASHLVTQLQSVISRNVNPLDSAVITIGKITGGTVQNIIAEKSRLEGTIRTLSVESMKRVKDRIEAIVAGIEAAFQCEAVIDYGAMYHQVYNHEALTKEFMEFASKDTNMNVVTCKEAMTGEDFGYMLRDIPGFMFWLGVDSEYGLHHAKLKPNEAAIDRAIEFLNQYVKWKGNRR
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: UPP_STRMU
Sequence: MGKFQIISHPLIQHKLSILRRKDTSTKHFRELVNEIAMLMGYEVSRELPLEEVEIETPITKTVQKQLTGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRDEETLEPVEYLVKLPEDIDQRQIFVVDPMLATGGSAVLAIDSLKKRGAANIKFVCLVSAPEGLKKLQEAHPDIDIYTAALDEKLNEKGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CTU1_USTMA
Sequence: MAPKLCVICNAERAVLRRPKTAQQICKECFFYVFETEVHHTIVSNNLFKRGDRVAIGASGGKDSTVLAHCMKVLNERYDYGLDLFLLSIDEGITGYRDDSLETVKRNQQQYQLPLKVLGYGELYGWTMDDIVKSVGRKNNCTFCGVFRRQALDRGAAALGVDHIVTGHNADDVAETVLMNVLRGDIARLERCTDIVTKGPDGSEDDQHQEGCGSSGSNGIGVGGSGIRRSKPFMYAYEKEIVMYAYFKKLDYFSTECIYSPNAYRGYARTFLKDLEAIRPSSIVDIIQSGQNLKVSQVVKQSRKTQLQNCLRCGYISSNTVCKACILLEGLEKGTPQLGIGSEKSRKIKDIRSENSKEVEKVSITADGKERKERRIPQWTGVAKDAPPISSLPFVPPQHKVDLSF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3BP5H_DROME
Sequence: MSSAEDGELDPQIQIELENLNSATDEINKLEIELEEANSTFRILLNESTRRLKVSSKKLGNCIEKARPYYEALDKAREAQIECQKAAVKFQRANEIHAAAKETVALAEQRFMSNSHEWQFDNAWQEMLNHATQKVMDAETQKADCHAEHQRLTKLFNAAEQKLQQLEDRFRRSINKSRPYFEEKQVCQDQLQTQKNRIQELQQQVAGAKSTYSTALRNLERISEDIHRQRGDFPTPPGPREPGVGAELNSPTSSALPSLPDFQLELEKCDYPSIAGSQMSLGAKTPQAAAETEDEEDACDYDETGAGELRGVVDERDLEALRQKVKILAVRPIEGGDGQQQNDVWEHELKATVDKLDHLMMLKETAKRQQTNRLKSTEQRPDSLGAEALKRHCDVVEVKVTSCATTASLPVTPHHQLNHLAPPTPIKKLQQQLAPLPSVNVSMRELPLLARLSNELLDRSSAAFGGVRKTLRRRSLE
What are the official names of this protein?
SH3 domain-binding protein 5 homolog, Protein parcase.
What is the protein family that this protein belongs to?
Belongs to the SH3BP5 family.
Protein: RL3_GEODF
Sequence: MNKGLIGKKIGMTQIFADDGRRIPVTVVEAGPCVVIQKKTKEKDGYNAIQVGFDAKEAAKANSATVGHCKAAGSGAFSFFRELRVDNVDSYNVGDVLNADLFAAGDVIDVTGTSIGKGFQGVIKRWGFKGGRSSHGSRFHRAPGSIGCSATPSRVFKNKKMPGQLGNERVTVQRLKVVRVDAADNLILVGGAIPGSTNGLVFIKDSVKAKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ARCA_BACC0
Sequence: MKHPIHVTSEIGELQTVLLKRPGKEVENLTPDYLQQLLFDDIPYLPIIQKEHDYFAQTLRNRGVEVLYLEKLAAEALVDKKLREEFVDRILKEGQADVNVAHQTLKEYLLSFSNEELIQKIMGGVRKNEIETSKKTHLYELMEDHYPFYLDPMPNLYFTRDPAASVGDGLTINKMREPARRRESLFMEYIIKYHPRFAKHNVPIWLDRDYKFPIEGGDELILNEETIAIGVSARTSAKAIERLAKNLFSRQNKIKKVLAIEIPKCRAFMHLDTVFTMVDYDKFTIHPAIQGPKGNMNIYILEKGADEETLKITHRTSLMEALKEVLDLSELVLIPCGGGDVIASAREQWNDGSNTLAIAPGVVVTYDRNYVSNTLLREHGIEVIEVLSSELSRGRGGPRCMSMPIVRKDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAP_GAHVM
Sequence: MAGITMGSEHMYDDTTFPTNDPESSWKIVLAGEKFMTASAALKTIVGCVKNPLITFSDDGLMIQGTVCGQRMFVPIDCTSFSEYEWRGPTAIFLALTDSRRTLLDAFKCDKKKVVEVCFTFRGEPPCRHLTQTVTYANDGCSFSSTIVKYELWSASIICPQKTPDATFSLNKQQLSKILTVAAKVQHEELIFALKAEGGFYAGTICDVISFDIDGSAMVQYPYNATSHASSALIVACGKKKTNKSIAVTAYGSGKPFCLALEDTNAFRNVVQKIKTGAAGADLGFYTTCDPPMLCVRPHVFGSPTAFLFCNSDCMSIYELEEVSAVSGAIKSKRISEYFPKVSNIGSRKRGPSSPPFEREGKLAKVINQ
What is the function of this protein?
Plays an essential role in viral DNA replication by acting as the polymerase accessory subunit.  Associates with the viral polymerase to increase its processivity and forms high-affinity direct interactions with DNA.  Facilitates the origin-binding protein UL9 loading onto DNA thus increasing its ability to assemble into a functional complex capable of unwinding duplex DNA (By similarity).
What are the official names of this protein?
DNA polymerase processivity factor, DNA-binding protein UL42, Polymerase accessory protein, PAP.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA polymerase processivity factor family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PROBL_OLEEU
Sequence: MSWQSYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNAPGHLVPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-4, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RPA12_HUMAN
Sequence: MSVMDLANTCSSFQSDLDFCSDCGSVLPLPGAQDTVTCIRCGFNINVRDFEGKVVKTSVVFHQLGTAMPMSVEEGPECQGPVVDRRCPRCGHEGMAYHTRQMRSADEGQTVFYTCTNCKFQEKEDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit H, Zinc ribbon domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.