PharMolix/UniProtQA huggingface dataset:
Protein: ATG17_KLUMD
Sequence: MSYHYDGIPDIEIDLYWNKARNHLLKAQVECEESLKLLSTIRSEMDSCQKSRLKLQFILNCLVNQVEFFSSVILEKCIAVELLDNEWSKVVLVGVVKDLNYWQDEITNKINALKNTKYDLNAEYKSLADFICEDHVEILQQKLDEVPFIKKQVSNIRQHYKSIKEGVQYQLKAGKVKKLKKYYETHFSRDNHLFELLEGEYLTKLNSYESELTDYIRSITDHFDKCSILKADGLPPQDLKDLFEVVKNDDAELEHIRELIYESDAEITQFYKNVEGTITSIKENVADFYGLSTKIMVELEKCEEYVSIFQDIAKLVSVYKESCIRKIEQVQELCEVYDKFKKAYFNLLKERERRKSVAIQMKSILDECKGKLMALNEDDLDHRQQFLHENGDYLPENIWPGKIDDMTPLYSLEYTIYNEQK
What is the function of this protein?
Autophagy-specific protein that functions with ATG13, ATG29, and CIS1/ATG31 in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation (PubMed:26442587).  Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles, through interacting with and regulating ATG1 kinase activity (By similarity).  Plays particularly a role in pexophagy and nucleophagy (By similarity).  With ATG13, is required for ATG1 activation by autophosphorylation (By similarity).  Recruits ATG9 to the pre-autophagosomal structure (By similarity).
What are the official names of this protein?
Autophagy-related protein 17.
What is the protein family that this protein belongs to?
Belongs to the ATG17 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: SPSS_METBF
Sequence: MKLDDSSLQKFGFIKRDTLGSINIDPLQTGGRLTEAAKQALVEWGDGYSVCDFCGGILDQIKKPPIYDFVHKALPEFLDCDEARVTNGARESKFAVMHSIGKPGDWIVLDGLAHYSSYVAAERAGLNIKTVPHSGSPDYYLDPEGYATAIEEVTKESGKPPALALVTYPDGSYGNLPDARKIASVCHEYDVPLLLNGAYAVGRMPVSAKEIGADFIAGSGHKSMAASGPVGVLGVSEEYAPIVFRKSKYNKVKEVELLGCTARGATVMTLIASFPDVVKRVRNWDQEVENARWFSARFEEMGFIQRGQKPHSHDLMFFEAPRFYEISEKVKKGRYFLYKDLKARNIHGIKSGLTKYFKLSTFGLGKEKLGIVADSFEEILKKYEDV
What is the function of this protein?
Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
What are the official names of this protein?
O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Sep-tRNA:Cys-tRNA synthase, SepCysS.
What is the protein family that this protein belongs to?
Belongs to the SepCysS family.
Protein: MGRB_ECO24
Sequence: MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AAEB_SALAR
Sequence: MGVFSIANQHIRFAVKLACAIVLALFIGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGMLRIIGTFIGCIAALIIIISMIRAPLLMILVCCVWAGFCTWISSLVRIENSYAWGLSGYTALIIVITIQTEPLLTPQFALERCSEIVIGIGCAILADLLFSPRSIKQEVDRELDSLLVAQYQLMQLCIKHGDSEEVDNAWGDLVRRTAALEGMRSNLNMESSRWVRANRRLKALNTLSLTLITQSCETYLIQNTRPELITDTFRELFETPVETVQDVHRQLKRMRRVIVWTGERETPVTLYSWVGAATRYLLLKRGVISNTKISATEEEILQGEPVVKVESAERHHAMVNFWRTTLSCVLGTLFWLWTGWTSGNGAMVMIAVVTSLAMRLPNPRMVCIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCLSLAVLGFFIGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCMLAFIVILLVRDKSKDRTGRVLLNQFVSAAVSAMTTNAARRKENRLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSVFHRQLRRTADHVISAGNDDKRRRYFGQLLDELDIYQEKLRIWEAPPQVTEPVKRLTGMLHKYQNALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_KLULA
Sequence: MLSRSAIRSASRSVVAANLVRSMNRVARPALVVAGRRFASAKAQPTEVSSILEERIRGVSEESNLNETGRVLAVGDGIARVFGLNNVQAEELVEFSSGVKGMALNLEPGQVGIVLFGSDRLVKEGEVVKRTGKIVDVGVGPELLGRVVDALGNPIDGKGPINASGRSRAQVKAPGILPRRSVHEPVQTGLKSVDALVPIGRGQRELIIGDRQTGKTAVALDTILNQKRWNNGTDESKKLYCVYVAVGQKRSTVAQLVQTLEQHDALKYSIIVAATASEAAPLQYIAPFTAAAIGEWFRDNGRHALIIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEKNGGGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKALKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLARGERLTQLLKQNQYSPLAAEEQVPLIYAGVNGYLDNIDISRIAEFETKFLAYLKANHDEIVSAIREKGELSKELLATLKSATESFVATF
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.  Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).
What are the official names of this protein?
ATP synthase subunit alpha, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Protein: RIMP_PORG3
Sequence: MIDREQIVRIVSDYLSTGETFLVEVAIHPGNRILVELDSAQGVCIDECVALSRHIESQVDRDLEDYELEVGSTGLTSPLKVMRQWENCIDSELSVLLTNGMKETGRLITVAPEAIKLEVVRMVKPEGAKRKKPETQELTIVMADIKQAVRII
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUBT_GEOSE
Sequence: MRSKKLWISLLFALTLIFTMAFSNMSVQAAGKSSTEKKYIVGFKQTMSAMSSAKKKDVISEKGGKVQKQFKYVNAAAATLDEKAVKELKKDPSVAYVEEDHIAHEYAQSVPYGISQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLNVRGGASFVPSETNPYQDGSSHGTHVAGTIAALNNSIGVLGVSPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPSGSTALKTVVDKAVSSGIVVAAAAGNEGSSGSSSTVGYPAKYPSTIAVGAVNSSNQRASFSSAGSELDVMAPGVSIQSTLPGGTYGAYNGTSMATPHVAGAAALILSKHPTWTNAQVRDRLESTATYLGNSFYYGKGLINVQAAAQ
What is the function of this protein?
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.
What are the official names of this protein?
Subtilisin J.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIO_STAAB
Sequence: MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAADYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDKHL
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: NFI_PICTO
Sequence: MQSIDLYSYLYSLLGQIPEGMVTTYGDLAVALGDVKAARACGYMLSRNNDTENIPCYKVIMSDGSLGGYSLGIDEKIRRLRNDGIEINNGRIDLKRYRFNNFDSSYPLKRLQEEQEKIAGLAVYSDDYNEDKICAIDVSYKDEIGYSVMVSFENNEYDFKTFIKETRFPYIPGYLAYREFPYIKELGKNFDGTMIIDANGLLHPRRCGLATYVGVIMNKPSIGVAKSLLTGSIKNGYVYYNNMPLGYMINSRTIVSPGNRISLESSINFIRNLGKDHYPEILKIAHDRTVALRRNNII
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity).
What are the official names of this protein?
Bifunctional methyltransferase/endonuclease.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1395_STRSV
Sequence: MKILIPTAKELNLTAPSAIPNPPLAQTQAVLDELATMSVAGLASFYKISPERAEIELQAIQALREGTAQHAPALYLFDGLMYRHIKRQDYTKEESQYIEKYLAITSALYGVIPALEPIAPHRLDFMMPLKLDGKSLKAFWKEAYDQALAEDEVIFSLLSSEFETVFSKKIRQRMIGFKFLEDRGDKLKVHSTISKKARGEFLTALITNQVTEVEQMKKLNFAGFTYRPDLSSEQEMVYVKEV
What are the official names of this protein?
UPF0246 protein SSA_1395.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: ZG67_XENLA
Sequence: SDRKTVSCPECGKCFTSRTYLNVHKKVHTGQTYSCSECGKSFLSRSHLNTHLRTHTGEKPYSCSECGKCFTSSAILITHKRIHTGERPFSCQECGKSFSYRSVFMEHQKIHTGEKPFSCSDCGKCFRYRSHLKVHSRIH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Gastrula zinc finger protein XlCGF67.1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PANB_SINFN
Sequence: MSVQTTKRRLSPASIEALKGERPIVSLTAYTTPIARLLDPHVDFLLVGDSLGMVLYGLDTTVGVTLDMMIAHGQAVMRGSERSCIVIDLPFGSYQESKEQAFRSAARILKETGCSAVKLEGGAEMAETVDFLVSRGIPVLGHVGLMPQLVNTTGGYRSVGRNEKEVAKIRRDAKAIDDAGAFAIVVEGTVEPVAREITATLRCPTIGIGASPACDGQILVSDDMLGIFNDFKPRFVKHFAELAPAISKAVEDYANEVKARTFPGIEHTFQVKR
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEN2_HUMAN
Sequence: MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
What is the function of this protein?
Transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3'.  Involved in regulating energy expenditure, body mass, voluntary physical activity, mating behavior and reproductive longevity, acting through the hypothalamic-pituitary-gonadal axis.  Acts as a transcriptional activator of target genes, including NDN, PCSK1, MC4R (By similarity).  Is also a transcriptional activator of KISS1 (PubMed:35066646).  May act centrally to regulate function of both white and brown adipose tissue.  Together with NHLH1, required to maintain migration and survival of cells in the anterior extramural migration stream (aes), which forms the precerebellar nuclei.  Also, in concert with NHLH1, may determine fate of gonadotropin releasing hormone-1 (GnRH-1) neurons.
What are the official names of this protein?
Helix-loop-helix protein 2, HEN-2, Class A basic helix-loop-helix protein 34, bHLHa34, Nescient helix loop helix 2, NSCL-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGR_MYCLB
Sequence: MTHGASKTTPETTRAGRQARIVAILSSTSVRSQSELATLLADDGIDVTQATLSRDLEELGAVKLRGADGGVGVYVVPEDGSPVRGVSGGTARLSRLLSELLVSADSSANLAVLRTPPGAADYLASAIDRAALPYVVGTIAGDDTVFVAAREPMTGSELATVLESLNR
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_CHLPM
Sequence: MRRKIVVGNWKMNKTVAESTELASAVVAALGSDCSACEAGIAPTYPALDSVGRTIKGSEVLLVAQNCHYEDDGAFTGEVSTGMLNALGCSYVIIGHSERRQYFGETDATVNLRIKKVLAAGMKAILCVGETLEERESGAFEAVVSTQVTGGLQGVVDISDIVIAYEPVWAIGTGRTASSEQAQEVHKIIRNKVAELYGAPAADAVRIQYGGSVKPSNAAELFAMPDIDGGLIGGAALKAEDFAAIVKAAC
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC24_CANAL
Sequence: MSGRRRAYPQPQYATGPAEMATPPAPNQFQQQQPVQQPVQQYGVDQMQGQFQQMNVGGVGPTGVPPAPQYSYQQPGQPQQSPQLSYDPYQPQPQANTGVYGQGMGGVPPSAVPAGGAGYGGYGQQNNIGLGAQLNALYTTDLSRDLPPPIAELSFQPPPITLPDNATLIPASKTANATPEYFRSTLNVVPTNSSLLKKSKLPLAIVVNPYNALKIENENVPVTCDTVISRCRRCRGYINPFVTLAENGRRWRCNFCNLLNDIPSAFDYDEISGQVKNKFDRVELNHSVVEFIAPKEYMARAPQPIVYTFIIDVSVHAIQSGLTGTITRTILESLDRIPNENKTARVSFIGVDSNLHYIRFNEGLEGTEILVVADIDEPFLPSPGGLLVNLDENREAIEKLLLDFPSYFENNANQGFALGPALKAGHKMISNIGGKLVCFAATLPNIGEGKLSVRDEASVAGKAKEAKALLAPADSFYKSFAVTCNSSQVTVDLFLTSSAYQDVATLSNLARYTAGQTHFYPAWTSNKYEDVAKLSKEVSDHLSQDIALEAVLRVRGSTGFRMSSFYGNFFNRSSDLCSFPTFPRDQSYLIEMSIEETINKPVVYFQAAVLHSTCFGERRIRVMNLALPTSSKLVDIYASADQLAIANYFTHKAIEKALSSSLPEAREYLIARVVDILNVYRKELVAGNVSGASPLQISTNLRMLPLLLFCLTKHLAFRGERVPSDHRAAALNNLGSSPIPQLIKSIYPTVYSLHNMPDTCGLPGVKEDEDDEEGAGAEIDVVLPDPINDSKASWENYGLYLIDNGSELFLWVSGNVVPGLVQDLFGTENLYEIPTGKTELPEFSLEESEFNYRVRQIIGKIREQNDSIIWKNLYVVVGASSNEPIEISQQRDLMALRMWASSCLVEDKTGSEPSYRDFLTSLKSKVSQ
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC24.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ABCC9_DICDI
Sequence: MIRNKIKNKKSKSDYYSEISLEEEEDKEEEIKDKKVLSKEEIKENENKNEKIKQTQCPEDNASLFSKITFGWITKLIVKAYIKKSLDIKDIFDVPNYLKSNYTSKFLTTEKQTFKRNTKYSLILNIYINFILLKNKKLILIQFLRVLFTLLSPLILKLFIEFTQRIDSEKSIIEGIIYCGLLFFSSFCSSLVDEYLVWFGMITSSQVKSCLTCLIFEKSLKLSNSAKVKYNAAKITNLISIDVDNFSNFFWSNSVEIFFQPFQLIFLLILLISEVGWSGFVGTAVILISFPINSYFGKKTSDYYEKLLKYTDKRVSTTSEFINGIRFIKMYAWESLFLKKIEKQRKQELKILLERGLFWLGQIIIINTNSTFVFVATMVTYSLSGNKMKLETAFTAMNILDSIRILLIVMPYCYYSIMELIPSNKRIEKFLSTLEIQQNLQTTKNSNTISINNGTFKWKDENFEETDDDDDHDDDDDEGEKEIEGKEEKEEINNFIFENINFKAPIGKLTMICSPVGSGKTSLINALIGEIEKVNGEINGVPENISFTSQQPFLLSTSLRENILFGKELDIEYYKQVLDACCLVSDLTQLSALDLTEIGEGGINLSGGQKQRVSLARALYSNSDFILMDEPLSAVDPEVANHLFEKCIQGMMKNKTRILVTHQIQFIPYADHIVIIKDGKIIQGTYKELKDENGIDFESIIKTKNSNLNLNKTIKDEEEKEDKEGEEKEEDKKEMILKLIKINYSDELKEKAKLLVEEDRNEGEVSFKTYKEYFYYGSSNLFLFITLLVFLIGLIVNRLSDFWLTIWTEQSFKEKSQTFYIICFVSIFIVSLILIFIRYSLVAKIGFKSSKKLHDLLINSISKSPIQFFDSNPSGRILNRFSNDISDIDTSMIDMFSDTLEYIFAIVVGIFSIIYINPMTIVPFLILSMFYYQIFNIYRVSVRELNRCKSISQSPIISFLSECCNGLSTIRAFKQQSRFIGIMNDNIDKNLKCEFASFAVEMWISIRLELLSSIIVFIVSLFSLFNGYSNSALSILSVSTARSITSYLKSACRQMVDLERKMNSFERVNNYIKLPSEGSGSGVKSMEFISEKDLLNWPEKGNIQFNNVQVNYNSNSVPSLKDITFSVESNEKIGIVGRTGAGKSTIANCLFRLVECSKGSILIDGIDIKTIDLNKLRGSLGIVPQEPWLFSGTIRSNIDPLNQYDDEMIWNYLEMVKLKKLIIEMPLKLNSKIHENGNTTLSYGQKQLLCLCRCLIKNPKLIIMDEATSSVDFQTAETIKSVINENLVNNTILTIAHRLDIIIDSDKIAVIDNSKLIEFENPKNLINSNSKFRKIVNFQTKIQTN
What are the official names of this protein?
ABC transporter C family member 9, ABC transporter ABCC.9.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CYSKP_CAPAN
Sequence: MASIINNPFTSLCCNTNKCEPNRICSLRSQQSLVFDNVNRKVGFPSVVCKAVSVQTKSPTEIEGLNIAEDVTQLIGNTPMVYLNTIVKGCVANIAAKLEIMEPCCSVKDRIGFSMISDAEEKGLISPGKTVLVEPTSGNTGIGLAFIAASRGYKLILTMPASMSLERRVILKAFGAELVLTDPAKGMKGAVSKAEEILNNTPDAYILQQFDNPANPKIHYETTGPEIWEDTKGKIDILVAGIGTGGTISGTGRYLKEKNPNIKIIGVEPTESNVLSGGKPGFIPGNLDQDVMDEVIEISSDEAVETAKQLALQEGLLVGISSGAAALAAIQVAKRPENAGKLIAVVFPSFGERYLSSILFQSIREECEKMKPEL
What are the official names of this protein?
Cysteine synthase, chloroplastic/chromoplastic, CSase B, CS-B, O-acetylserine (thiol)-lyase, O-acetylserine sulfhydrylase, OAS-TL B.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chromoplast.
Protein: HUPQ_AZOCH
Sequence: MIGTQSILPPGFGPGSHGEEDRLDYLPMPREMHTFERPSLPEPEQLDSHPIALALLERLQEALTAYRIGEQSRVIGLDRQPKADLKLLQQILGEGEVAIQVGGQRPVRIQETVLAGVWWVQLQVGLGEVVGQWLEVADIPALVRRRAFAEARWPRLGATLPDDLLNAGPVLVELLEAAKQHAEHASATPHVINLSLLPFSAEDQRFLAEQLGEGPVTVLSRGYGNCRIASTATPGIWRVQYFNSTDRLILDTLEVTAIPQAACAAQEDIDDSAERLREIREALE
What are the official names of this protein?
Hydrogenase expression/formation protein HupQ.
What is the protein family that this protein belongs to?
Belongs to the HupH/HyaF family.
Protein: F1712_XENLA
Sequence: MGRARDSGKRSGGPPCSFLLLLLLSCGGGRGKSLLGAAGAQDFHIKVQVYENGDLSPLASAAVEIFGNQSSLASGVTDQDGVAVLGISYRLGTWVLVSATKRGFVTNSVPWRVDRLPLYASVSLYLVPERPATLILYEDIVQILLGSPGARSQPWVQFQRKAARLPRSSTYNQLTSSLTTASTRHQMRGFPAFIGTEPESANGGNTSWVELLPVAAISVHLFSGNGSEVHLSGPVQLSLPLPPESGLTTSSSVPAWRYEPKVGVWIRSGMGLVRRDGQQLYWSFVSPKLGYWAAAIPSSGRGMLSLMSGVDIAGYHTIFLLSILGALTLLVLILLCLLIYYCRRRCLKPRQQHHKLQLSGLSEPKRDQATSTSRLNLISTSHLDSTSTADSDLRTPVLRSAFSSREDFCKSGGRSSFQHSADTLPLRPGSRDEYPLKSARSGDLLESEDSKRGYGTGGKGQQRRRGGRGGVRDPPPSPPPLPPPFKHVIGDSKPPDYLMTQSADPLSRPTSLTQPGQFIFCGSIDHMKEGSYRHAMPTLVIPAHYMRLSSEENQGGQGEEQSESESGSTQVSHAHHFAPQDHAQRQQLLQQGHGYQQGATASSQDQEGKGWGNHGSVTIPVVFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNAQVRHSYIDLQAGDKTRSNDASLDSGVDVNEIKVKLGPEERSGKAQLQPSNLTYSKLVFAEEGEQSLSESRTGGGCSPEDSSLTPLLDEGSETCLPMSRRGRSRGDSSRSSTSELRRDSMTSPDEDLNDQSEGGDDQDKKSPWQKREERPLMVFNVK
What are the official names of this protein?
Protein FAM171A2.
What is the protein family that this protein belongs to?
Belongs to the FAM171 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GT251_MOUSE
Sequence: MAALPRGSRGLPLLPLLLLLPPLGGPRGADGYFPEERWSPESPLQAPRVLIALLARNAAPALPATLGALEQLRHPRERTALWVATDHNTDNTSAILREWLVAVKGLYHSVEWRPAEEPSSYPDEEGPKHWSDSRYEHVMKLRQAALKSARDMWADYILFMDIDNLITNPDTLSLLIAENKTVVAPMLDSRAAYSNFWCGMTSQGYYKRTPAYIPIRKRDRRGCFAVPMVHSTFLIDLRKAASRNLAFYPTHPDYTWSFDDIIVFAFSCKQAEVQMYVCNKEVYGFLPVPLRAHSSLQDEAESFMHVQLEVMVKHPPVQLSRFISAPRKTSDKMGFDEVFMINLKRRRDRRERMLRALHEQEIDCQLVEAVDGKAMNTSQVEAMGIQMLPGYRDPYHGRPLTKGELGCFLSHYNIWKEVVDRGLQKSLVFEDDLRFEIFFKRRLMNLMRDVEREGLDWDLIYVGRKRMQVEHPEKAVPHVRNLVEADYSYWTLAYVISLQGAQKLLAAKPLAKMLPVDEFLPVMFDKHPMSEYKSHFSPRNLRAFSVEPLLIYPTHYTGDDGYVSDTETSVVWNNEQVKTDWDRAKSQKMREQQALSREAKNSDVLQSPLDSTARDEL
What is the function of this protein?
Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen.  By acting on collagen glycosylation, facilitates the formation of collagen triple helix.  Also involved in the biosynthesis of collagen type IV.
What are the official names of this protein?
Procollagen galactosyltransferase 1, Collagen beta(1-O)galactosyltransferase 1, Glycosyltransferase 25 family member 1, Hydroxylysine galactosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 25 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Note=Colocalized with PLOD3 and mannose binding lectin.
Protein: Y1414_MYCTO
Sequence: MLGDAQQLELGRCAPADIALTVAATVVSRQDCRSGLRRIVLDCGSKILGSDRPAWATGFGRLIDHADARIAALSEHHATVVWPDDAPLPPVGTRLRVIPNHVCLTTNLVDDVAVVRDATLIDRWKVAARGKNH
What are the official names of this protein?
Uncharacterized protein MT1457.
Protein: GLSA_SHESM
Sequence: MPEQALLEEVVDKVRPLLGQGKVANYIPALANVDAGKLGIAVTTIDGETIGAGDYLEPFSIQSISKVFSLTLALTLYEETEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRALSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTLDGTELISQVQTRQLNALLATSGLYDGAGEFAYRVGMPGKSGVGGGIIAVIPGELSVCVWSPELDNQGNSLAGTAMLEHLSQRLGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: SPT5_ASPOR
Sequence: MSRNMLDHDFGSDEEDDDFNPAPAYDSDNEDARPTHQDRDDDDDEEDVKPSRRAERRVGSEEADDNEDADGHDDEEEDENDDDDEEEEDEDEEGAVSRPKKRRRKGGVAHFFEEEAGVDEDEDEAEDEEDEMAELGGEMHPDDMDALPVGAETDDRRHRQLDRQRELEASMDAEKQAQLLKERYGRNRAAASDAVVVPKRLLLPSVEDPSIWGVRCKPGKEREVIFAIQKRIEERPMGSRNPMKIISAFERGGAMSGYIYVEARRQADVMDALQDMSNVYPRTKMILVPVREMPDLLRVQKSEELLPGGWVRIKRGKYQNDLAQIEEVETNGLAVTVRLVPRLDYGMNEDIGAPFMDPKRKRPGMNPAVARPPQRLFSEAEAKKKHGKYLSATSGLGGKSWSYLGETYVDGFLIKDMKVQHLITKNVSPRLEEVTMFARGSEDGTANLDLASLAETLKNSTAEDSYLPGDPVEVFRGEQQGLIGRTTSTRGDIVTLQVTEGDLAGQHIDAPVKSLRKRFREGDHVKVIGGSRYQDELGMVVQVKDDTVTLLSDMSMQEITVFSKDLRLSAETGVDGKLGMFDVHDLVQLDAATVACIVKVDRESLRVLDQNGSIRTILPTQVTNKITPRRDAVATDRNGAEIRHGDTVREVYGEQRNGVILHIHRSFLFLHNKAQAENSGITVVRTTNVVTVSAKGGRSTGPDLTKMNPALMSRGGPSGMMGPPKSFGRDRMIGKTVMVRKGPFKGLVGIVKDAGDVQARVELHSKNKLVSIPKELLVVKDPVTGQTIEMGRGRGGPRVPSAAPPSGWQGGRTPMAAADSSRTPAWGGASSARTPAWAGMGGSRTPAWKNDGSRTSNPYDGSRTAYGGFGSRTPAWNAGARTPYGGSGSGQSDFDAFAAGSRTPAWNANSGSRTPAWSGATASNGSKDSRGYDAPTPGGAYSAPTPGAYASAPTPGVSAPTPGAWADSAPTPGAFNAPTPGGPSKKPYDAPTPAAWDSRPYDAPTPAMGGDGDDAGPRYEDGTPSP
What is the function of this protein?
The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing.  This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
What are the official names of this protein?
Transcription elongation factor spt5, Chromatin elongation factor spt5.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: H4_DROSI
Sequence: MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MDLB_ECOL6
Sequence: MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPLLISYFIDNMVAKNNLPLKVVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAMFSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQQFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSASGTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDRPLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQALETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASIDSGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQGRYWQMYQLQLAGEELAASVREEESLSA
What are the official names of this protein?
Multidrug resistance-like ATP-binding protein MdlB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.