PharMolix/UniProtQA huggingface dataset:
Protein: SURE_SULDN
Sequence: MRYKILVTNDDGYEAKGLRALVKALKELEDVEVMVVAPASEKSACGHSLTLVRPLRFVGVDDNFFKLDDGTPSDCVYLALSTIYVDSKPDLLISGINRGSNMGEDITYSGTAAGAMEGVLHDVPSIAISQVMDFSDPQGDFTLAQKVIKELVIKIKNGSFPLPQREFLNVNIPPDLDSTDNRDAKMVVTYAGYRFYANDSHIHRNPRGEEFYWLGLHPLDFLPREGIKGISDYEAIEAGNISITPIQLDMSAYKSMNKLKEWIE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPI1_VAR67
Sequence: MIYIIYRYRYCLVYTMDIFKELILKYPDENVLISPVSILSTLSILNHGAAGSTAEQLSKYIENVNENTPDDKKDDNNDMDVDVPYCATLAIANKIYCSDSIEFHASFLQKIKDDFQTVNFNNANQTKELINEWVKTMTNGKINSLLTSPLPINTRMTVVSAVHFKAMWKYPFSKHLTYTDKFYISKNIVTSVDMMVSTENDLQYVHINELFGGFSIIDIPYEGNSSMVIILPDDIEGLYNIEKHITEENFKKWCGKLYTKSIDLYMPKFKLKMTESYNLVPILENLGLTNIFGYYADFSKMCNETITVEKFLHKTFIDVNEEYTEASAITGVFMTNFSMVYRTKVYINHPFIYMIKDNTGRILFIGKYCYPQ
What is the function of this protein?
Plays a role in mediating viral host range.  May act to inhibit a caspase independent form of apoptosis to allow efficient virus replication in infected cells.
What are the official names of this protein?
Serine proteinase inhibitor 1, Serp-1, Serpin-1.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Poxviruses subfamily.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PXPA_THEKO
Sequence: MKVDLNADLGESFGRYRLGLDEEVMKYITSANVATGWHAGDPLVMRKTVKLAKENGVAVGAHPGYPDLLGFGRRYMKLTYDEARNYILYQVGALYAFVRAEGIELQHVKPHGALYNALVKEEELARGVIEGIADFDKNLIFVTLSGSRPAEIAEEMGVKVAHEVFADRAYNPDGTLVPRSKPGAVIEDKEEIAERVISMVKDGGVRAINGEWVELKVDTICLHGDNPKAVEIAAHIRKVLEEEGVKIVPMKEIIR
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: EFEMO_STAAW
Sequence: MKKLTTLLLASTLLIAACGNDDSKKDDSKTSKKDDGVKAELKQATKAYDKYTDEQLNEFLKGTEKFVKAIENNDMAQAKALYPKVRMYYERSEPVAEAFGDLDPKIDARLADMKEEKKEKEWSGYHKIEKALYEDKKIDDVTKKDAQQLLKDAKELHAKADTLDITPKLMLQGSVDLLNEVATSKITGEEEIYSHTDLYDFKANIEGAQKIYDLFKPILEKKDKKLSDDIQMNFDKVNQLLDKYKDNNGGYESFEKVSKKDRKAFADAVNALGEPLSKMAVITE
What are the official names of this protein?
Efem/EfeO family lipoprotein.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYS_STAAM
Sequence: MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDIEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERMC2_STAAU
Sequence: MNEKNIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQVLNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVFDSIADEIYLIVEYGFAKRLLNTKRSLALFLMAEVDISILSMVPREYFHPKPRVNSSLIRLNRKKSRISHKDKQKYNYFVMKWVNKEYKKIFTKNQFNNSLKHAGIDDLNNISFEQFLSLFNSYKLFNK
What is the function of this protein?
This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.
What are the official names of this protein?
rRNA adenine N-6-methyltransferase, Erythromycin resistance protein, Macrolide-lincosamide-streptogramin B resistance protein.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: RLMN_STRR6
Sequence: MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEEMTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLSVCVTTQVDCNIGCTFCASDLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVSHIVVMGIGEPFDNYNNVLNFVCTINDDKGMAIGARHITVSTSGLAHKIRNFADEGVQVNLAVSLHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDSVEQALELAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEYGTDIDAACGQLRSNTMKRDRQKAVAEVNP
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_CALBD
Sequence: MVVVQKIQEMKEIAKKLKKEGKSIGFVPTMGYLHEGHLSLVRLSKQQNDITIMSIFVNPIQFGPNEDYDRYPRDFERDKSLAEKEGVDYIFYPSVEEMYPEDFKTVVSVKKITEIMCGKSRPGHFDGVATVVLKLFNIVNPDRAYFGQKDAQQLAVIKQMVKDLNLDVEIVPCPIVREQDGLAMSSRNVYLSEEERKSATVLYRALNLAKEMIEKGQKDVSSIKRAMEEMILKEKYTKIDYIEFVNNDTFEIISKVEGKVLIALAVFVGKARLIDNIVVEAK
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TES_NEONE
Sequence: MDLEAKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKTDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPREMDTQGPNRMLLPGGDRSTTAAVGAMEGKSAEPKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSACQELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: FABZ_RICRI
Sequence: MIIDITEIMDWIPHRYPFLLVDRVLKIDPNKSITGIKNVTVNEPQFTGHFPARPVMPGVLMVEAMAQLAAILVAKSLGSTKNKEVFLMTIENAKFRRIVQPGDTMHIHAVIDQQRANVWKFSSTVTVEGEIAAESKFTAMIKDKT
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRC22_YEAS1
Sequence: MRFSMLIGFNLLTALSSFCAAISANNSDNVEHEQEVAEAVAPPSINIEVKYDVVGKESENHDSFLEFYAEDTATLAYNVTNWEDTNITIFGVNGTIVTYPHGYPVADITGASIGPYEMEVNGTSKFGQDVTLNLPEGQYFLIPFLLASRFDEIVRIAAPPTLFEIVSPPISFFNPQFLSVQVIFLAIIGGVSYYYMKSKTNQRPSKKSATVKKVDESWLPETYKK
What is the function of this protein?
Is probably involved in a pathway contributing to genomic integrity.
What are the official names of this protein?
Increased recombination centers protein 22.
What is the protein family that this protein belongs to?
Belongs to the IRC22 family.
Protein: GCH1_CHLTE
Sequence: MKQEKTVSPTVENNRSAESRLSQCDLDECFDESHDRDEEVLGSMTDAVYSLLKGVGEDPEREGLLLTPERVAKSLRFLTKGYRQDPEQLLKKAVFTESYDEMVLVKDIDIYSMCEHHMLPFFGKAHVAYIPDGKIVGLSKIPRVVEVFARRLQVQERLTQQIRDAIQNVLNPRGVAVVIEATHMCMVMRGVEKQNAVTTTSAMSGDFMTSQSTRSEFLRLIGNH
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GLMM_BRUSU
Sequence: MTRKFFGTDGIRGQANSFPMTPEIAMKVGMAVGYIFRRKGQASRVVIGKDTRRSGYMLENALVAGFTAAGMDVFLLGPIPTPAVAMLCRSLRADIGVMISASHNPFYDNGIKLFGPDGFKLSDQIELQIEAMIEGDMTPFLASHGDVGRAKRVDGDIYRYIEFAKRTLPRNISLNGLRVVVDCANGAGYKVAPAALWELGAEVITINNEPNGININEDCGSTHPIGLMKKVHEVRADVGIALDGDADRVLLVDENGTVIDGDQLMAVIAESWAASNRLEGGGIVATVMSNLGLERFLADRNLTLARTKVGDRYVVEHMREHGFNVGGEQSGHIVLSDFATTGDGLISALQILAVAQEQNKPISDVCRKFQPVPQLLKNVRTTGGKPLENKRVKSAIDEAKERLGGQGRLVIRPSGTEPLIRVMAEGDDRGLVEKVVNDIIDVISSESSAAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SC6A4_MACMU
Sequence: METTPLNSQKQLSACKDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPAATTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLIPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIILGYCIGTSSFVCIPTYIAYRLISTPGTFKERIIKSITPETPTEIPCGDVRLNAV
What is the function of this protein?
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization.  Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems.  Terminates the action of serotonin and recycles it in a sodium-dependent manner.
What are the official names of this protein?
Sodium-dependent serotonin transporter, SERT, 5HT transporter, 5HTT, Solute carrier family 6 member 4.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Synapse. Cell junction, focal adhesion. Note=Could be part of recycling endosomes. Density of transporter molecules on the plasma membrane is itself regulated by STX1A. Density of transporter molecules on the plasma membrane is also regulated by serotonin (By similarity). Density of transporter molecules seems to be modulated by ITGAV:ITGB3 (By similarity).
Protein: AAKG1_RAT
Sequence: MESVAAESAPAPENEHSQETPESNSSVYTTFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLEAIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQALVLTGGEKKP
What is the function of this protein?
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.  In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.  AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.  Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.  Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits.  ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit.  ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
What are the official names of this protein?
5'-AMP-activated protein kinase subunit gamma-1, AMPK gamma1, AMPK subunit gamma-1, AMPKg.
What is the protein family that this protein belongs to?
Belongs to the 5'-AMP-activated protein kinase gamma subunit family.
Protein: TPE_PELSA
Sequence: MFTLKKSLLLLFFLGTINLSLCEQERDAEEERRDGTDESDVEVEKRFLPALAGIAGLLGKIFGK
What is the function of this protein?
Non-amphipathic mildly cationic alpha-helical antimicrobial peptide with potent activity against Gram-positive and Gram-negative bacteria, and some fungi, as well as against Trypanosoma and Leishmania (both promastigote and amastigote forms).  Strongly and selectively perturbs anionic bilayer membranes by interacting with the polar head groups and acyl region of the phospholipids, with formation of regions of two coexisting phases, one phase rich in peptide and the other lipid-rich.  Shows low hemolytic activity and a low toxicity for human monocytes THP-1 and THP-1-derived macrophages.  Is not toxic to human hepatoma-derived cells.
What are the official names of this protein?
Temporin-SHe, Temp-SHe.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Deeply inserts into the lipid bilayer.
Protein: RS8_CAMHC
Sequence: MLNDLISDGLTRIRNASMRRLDTTKLLHSNVVESVLKILAEKGYIESYNLIEEDNKKFINVVLKYNEHGKSAINEITKISKPGRRIYQTKDEIKRFKNGYGTVIVSTSKGVMSGIEASKAGVGGEVLCTVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL13_DEHMC
Sequence: MNTYTVKANDIKRDWHVIDASGRVLGEVAAEAAKYLMGKHKPMFCRNLDCGDYVVIVNAKKITVTGNKLDQKMYYRHSGFPGGFRQEKLGDLLKTKPLFVIEHAVKGMIPRNTLGAQILAKLKVYEGAEHPHASQTGVVSKES
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PSBL_CRUWA
Sequence: MTQSNPNEQSVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MTNB_KLULA
Sequence: MSDTSETICSMCQLFYVNKWVLGTGGGIGIKQDNIAYISPSGIEKELLEPEQIVKYNIQDDTYQCGAPGLKPSACTPLFLELFKTLGASCVIHTHSINAVLCSMIYEKEFTIKDIEQIKAIPKGDGTNLRNVDTLRIPIIDNAPEEQDLMPALKQMIKDYPNACAVLVKRHGLFVWGPTPKKAKIYIESIDYLFEVALKMKELGQ
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_NANEQ
Sequence: MEYNYFELLERAYQKLKDVIKQEQIRWNPPIPHIEYVKNRTIITNFKQIANYLNRDPKIIAKFFSKELFVQTIIEGNSLIINKRVSYETIKKKLDEFINIFVICPVCKRPDTELIERGRKIYYIKCHACGSESPVNYEL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: PLSC_NEIMB
Sequence: MSSNKASFFTRLRRLCRLAVWLFKTGKNLRGIDGGCPESRNRAVIELGRGVLAALDIGLEVGRPAPEHPNGVLVAANHVSWLDIFAMSAVYPSSFIAKQEIKSWPVLGKMGQNAGTVFINRNSRRDIEPINRAVCETLQRGQNVSFFPEARTSSGLGLLPFKAALFQSAIDAGAKVLAVALRYYDETGKRTARPSYADVGLPTCLWRIVSMKKLTIRVDFVCVADAAESEDRYALKDKIEESIRAVVADDADIAV
What is the function of this protein?
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position.
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase, 1-AGP acyltransferase, 1-AGPAT, Lysophosphatidic acid acyltransferase, LPAAT.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FDHE_ECOLI
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCDTYLKILYQEKDPKIEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_STACT
Sequence: MIYGIGIDLIEIGRIKTLMERQKKLPERILSKDELTKFESFSHEQRRAEFLAGRFACKEAFSKALGTGLGKHVSFQDINCQNDELGRPYIRYEGFKVHVSITHTENYAASQVILEKM
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_HAHCH
Sequence: MIDAEGYRPNVGIILCNPQGEVFWARRIGQDSWQFPQGGIKKDESPEEALFRELKEEVGLPPEAVEIVAGTRGWLRYRLPKKMIRYDSHPVCVGQKQKWFMLQLLADESEICTNYTDKPEFDGWRWVSYWYPLGQVVSFKREVYRRAMREFAPVLFKREES
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RL29_HALMA
Sequence: MTVLHVQEIRDMTPAEREAELDDLKTELLNARAVQAAGGAPENPGRIKELRKAIARIKTIQGEEGDLQENE
What is the function of this protein?
Stabilizes the tertiary rRNA structure within the 23S rRNA domain (domain I) to which it binds.  Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L29, Hl33, Hmal29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: LIPB_ECOL5
Sequence: MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_HELPJ
Sequence: MKFSVLTLFPQLILPYFEDSILKRALEKNLFELEVLNLRDFSANKYQKADHTLIGGGAGQILDPEMIENALHSVKNPKHTIFLSAVGKPFKQIDAMRLAQKKHVVLVCGRYEGFDERSIELGADEVFCIGDFILTGGELGALCLIDSIARHIQGVLGNAQSLENESFENNYLETPNFANAVFKSKEINKIPAPLEYSKGNHAKIKQLKLDLSKLRTKFYRLDLFKQHKS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_CAMJ8
Sequence: MKNEVKKVVLAYSGGLDTSIILKWLQDEYNCEVVTFTADIGQGEELEPARKKALSLGIKEENIFIKDLRDEFVKDYVFPMFRANAIYEGEYLLGTSIARPLIAKTQAQIALQTGADAVSHGATGKGNDQVRFELGYLAFNPDLKIIAPWREWDLNSREKLLAYAQKHGIDISKKKGKSPYSMDANLLHISYEGLVLEDPAHAPEEDMWRWSKSPKDAPNESEIIELDFQKGDLVAINGEKLSPAGLLTKLNELGCKHGIGRLDIVENRYVGMKSRGCYETPGGTILLKAHRALESITLDREAAHLKDELMPKYASLIYNGYWFSPERMMLQALIDESQIHANGRVKLELYKGNVMIIGRESANDSLFNAAYCTFEEDEVYNQKDAAGFIKLNALRFIIAGKNGRKF
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_CHLTA
Sequence: MHFLSPAKLNLFLQILGRREDDFHEIVTRYQAIAFGDQLSLSISSRDSLQVINACHLETPSNSIWKSVALFRRYTGITTPVSWRVVKQIPVGAGLAGGSSNAATALFALNQIFKTGLSDEEMRSLAEQLGVDTPFFFSTGAALGVARGEKIIALEESVSDRYVLYFSSEGVLTSRAFAAVQPSDCSSRKNLEYTQNDLEKPVFRLRLDLKEKKHWLESLWAELPVYIGLTGSGATLFVRYPEILEKDLSYAAQIQRAVTLSGGLLTSPIRRDPTAWYSIYSESALAAT
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.