PharMolix/UniProtQA huggingface dataset:
Protein: THIE_STAAB
Sequence: MFNQSYLNVYFICGTSNVPSHRTIHEVLEAALKAGITLFQFREKGESALKGNDKLVLAKELQHLCHQYNVPFIVNDDVSLAKEINADGIHVGQDDAKVKEIAQYFTDKIIGLSISDLGEYAKSDLTHVDYIGVGPIYPTPSKHDAHTPVGPEMIATFKEMNPQLPIVAIGGINTSNVAPIVEAGANGISVISAISKSENIEKTVNRFKDFFNN
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: SUCC_BURP1
Sequence: MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYSNQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEADDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: YMA6_VICFA
Sequence: MMYSIKTRKIRRNKIRLHKGSVREHQERGSDQVRDWIKNSVLKDYGLSSTVRSIKSFSKVSSRCVYGILLERVVYIAPDKFFPFSFVHLSPLHFWINQPAISFSTSLFSLLKVKQNFNLTRHELVLTVRLILIQRQLILILILRVGGGSYTQPS
What are the official names of this protein?
Uncharacterized mitochondrial protein ORF154.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LPXC_SOLUE
Sequence: MRFETTVQRPVEASGVGLHSGVPVKIRILPAPVSTGVVFVRTDLDGFQIPASWRHVARVSYATSLMRQGVLISTTEHLLSVFYSMGIDNVYVEIDNLEVPILDGSGLPFVKLIAQAGIRQYRRKRRYLRIRRPISVEDKGKRISILPDEAFRLTCDTEYPAPVGRQSLELVVTPEHYASELAFARTFGWENDLDQMRNMGLIRGASLANAVCFTSEGPLNPDGLRAVDECCRHKALDLIGDLALLGRPLLGHVIAERAGHAMHAALVARIMGDPSIYEIITFDQLASRVTQALVS
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: GREA_HELPY
Sequence: MNKEPMSMHGYNKICAELKQLKEVERPNIVKEIDIARGHGDLKENAEYHAAKEKQRFIEARIVDLSEIVANAQVIDPSALAHNKVSFGSTIKILNLDNDKEFSYTIVGSVESDPAKGLISFGSPIAKSLIGKSKGDAVSIQLPNGESDFEILDIYYKEICFDEN
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: YTDC2_MOUSE
Sequence: MSRPSSVSPRPPAPSGGGTGGGGGGSGGGGGGGGGGPASCGPGGGGRAKGLKDIRIDEEVKIAVNIALERFRYGDQREMEFPSSLTSTERAFIHRLSQSLGLVSKSKGKGANRYLTVKKKDGSETAHAMMTCNLTHNTKHAVRSLIQRFPVTNKERTELLPKTERGNVFAVEAENREMSKTSGRLNNGIPQVPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCRIFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQREEKQQTTLTEWYSAQENTFKPESQRQRAVASVSEEYDLLDDGGDAVFSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDVDAFAQVFHLILTENVSVDYRHSETSATALMVAAGRGFTSQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSASLEFGNLDESSLVQTNGNDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAILIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCTIADFLMKAPEPPPALIVRNAVQMLKTIDAMDAWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGTFSDHMALLRAFQAWQKARSDGWERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVDRENVILTGPKEKKVRFHPTSVLSQPQYKKIPPANGQAAAIQALPTDWLIYDEMTRAHRIANIRCCSAVTPVTVLVFCGPARLASNALQEPSSFRADGIPNDSSDSEMEDRTTANLAALKLDEWLNFKLEPEAASLLLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSTADTEFADGSTTGERVLMKSPSPALHPPQKYKDRGILHPKRSTDDRSDQSSVKSTDSSSYPSPCASPSPPSSGKGSKSPSPRPNMPIRYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSMVYLVFSVQGSGHFQGFSRMSSEIGREKSQDWGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQELEPQVGEQLLQLWERLPLGEKTTSD
What is the function of this protein?
3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells (PubMed:28380054, PubMed:28809393, PubMed:29033321, PubMed:29087293, PubMed:29360036, PubMed:32470506).  Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability (PubMed:29360036).  Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs (PubMed:29033321).  Acts by binding and promoting degradation of m6A-containing mRNAs: the 3'-5' RNA helicase activity is required for this process and RNA degradation may be mediated by XRN1 exoribonuclease (PubMed:29033321).  Required for both spermatogenesis and oogenesis (PubMed:28809393, PubMed:29033321).
What are the official names of this protein?
3'-5' RNA helicase YTHDC2, Keen to exit meiosis leaving testes under-populated protein, Ketu, YTH domain-containing protein C2, mYTHDC2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region.
Protein: NDUF7_XENTR
Sequence: MSGLARLRKTAFLMVSASANCRIQRYQSSRTEKHQDSTSANALLNHLIFKIKSTGPITVSEYMREVLTNPVKGYYMHHDMLGEHGDFVTSPELSQIFGELLGVWCISEWMSAGKPKSLQLVELGPGRGTLTDDLLRVFSNFGRLLNSCDISVHLVEVSPKLSDIQAQRLTGKAIEVELDKNSPVYKKGITKTGFPVCWYQDIQDVPTGFSFYIAHEFFDALPIHKLQKTKDGWREILIDIDPGIPDKLRFVLGPNVSLVANTFVQDDEPRDHVEVCPSAAVIIQKLANQINSYGGAALIADYGHMGERTDTFRGFRAHKLHDVLSNPGTADLTADVDFNFMRRIVGEAASCLGPVTQHEFLKNMGIDIRLKVLLEKSSDVAVQKQLIHGYNILMNADQMGQRFKFFSVVPQSRLKTTMPPVAGFSKLLMH
What is the function of this protein?
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).  Acts by mediating symmetric dimethylation of 'Arg-118' of ndufs2 after it assembles into the complex I, stabilizing the early intermediate complex.
What are the official names of this protein?
Protein arginine methyltransferase NDUFAF7, mitochondrial, NADH dehydrogenase [ubiquinone] complex I, assembly factor 7, Protein midA homolog.
What is the protein family that this protein belongs to?
Belongs to the NDUFAF7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYP22_ARATH
Sequence: MSFQDLESGRGRSTRKFNGGRQDSTQAVASGIFQINTGVSTFQRLVNTLGTPKDTPELREKLHKTRLHIGQLVKDTSAKLKEASETDHQSGVNPSKKIADAKLARDFQAVLKEFQKAQQTAAERETTYTPFVPQSALPSSYTAGEVDKVPEQRAQLQESKRQELVLLDNEIAFNEAVIEEREQGIQEIHQQIGEVNEIFKDLAVLVNDQGVMIDDIGTHIDNSRAATSQGKSQLVQAAKTQKSNSSLTCLLLVIFGIVLLIVIIVLAA
What is the function of this protein?
May provide the t-SNARE function in the vacuolar assembly.  Promotes the formation of vacuolar membrane 'bulbs'.  Required for inflorescence stem gravitropism.
What are the official names of this protein?
Syntaxin-22, AtSYP22, AtVAM3, Protein SHOOT GRAVITROPISM 3.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Prevacuolar compartment membrane; Single-pass type IV membrane protein. Vacuole membrane; Single-pass type IV membrane protein. Note=Prevacuolar compartment (PVC) in roots, and junction of two vacuolar membranes in shoot apical meristem.
Protein: CLPX_STAA3
Sequence: MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTNILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNILTQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEETEPELYDAEGNLINNSKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: THIM2_CLOBH
Sequence: MQIRQSIKLKKPLIHYITNPISINDCANIILAAGAKPIMAEHPLEVSEITSVSKSLGVNLGNITDNKMKSMLISGKTAYENKIPQVIDLVGVGCSKLRLDYAKKFISECHPNVIKGNMSEIKAIYGIKSSAKGIDVGACDIITKQNFDENIEMIKRLSMETGSVVAATGVVDIISNGTYTYIISNGCEMLSMITGTGCMLTGLIASYISSENILDGTVLAVALMGICGELSQHAKGTGSFRNELTDNMFSISDDIIIKKIRINSY
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase 2, 4-methyl-5-beta-hydroxyethylthiazole kinase 2, TH kinase 2, Thz kinase 2.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: SYC_ECO55
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPE_DROME
Sequence: MASARNLLLLSSSRLHGHGYLEHARGQLEDLFKSANVKTVLFVPYALRDHDKYTATVRDALQPWGFNVEGLHTKPDREQALREAQAIFVGGGNTFVLLRSLYEMKLLDPIRELVLQRGLPYVGSSAGTNVATRSIHTTNDMPVAYPPSFEALALVPFNINPHYLDPEAGSRHKGETRDERLEEFVAYHGLPVLGLREGTSVRVQGEKAILLGDRNAKLFKADGGTEELAPLADLTFLLQK
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.
What are the official names of this protein?
Probable alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP110_VANPO
Sequence: MDHTGEQNIQSVKSYEFTPIGYIKEKQNNGASKRPNESPIKESMQDTFRNESPPRKVRRTSIDDAMNSRMFNDSMQFDDTLPELDVNLQSSKLTSINMNKKNLIKELKENSNASNPLKEQQEQLSKLTTENYNLKLKCNSLLKVLNNVTDQGELRKSLEFLDEIEEWKSKYSTANSEFNLLKIKYDDLVIKFRNLESKVDEQESEVEDHTRCIIERDNLQNKIDKLSEELGTLNDKLDTITKELIAKDELIASNEEDIKQLNSHIDTLKNTIRGLEETIIEKDDNLKKQKDEIKTLNNNLNDSDHLGSEFLLLQNKLKEKNSQISVLENNLIDSKNTATELKTRLENLQKEYDDKLREKINQIHKLDDNIKQLKSERDSKYVSLDTNDKVRKDFERMRENNANLDSKLSQISNENKLFRDKISKLSNQLDDTKRERDNQVELMKRRIDEIITNNNRENSIAADKSEEIREKQEAHINELQRKLNDTLKVQTLSISTVEDKFKAEILKTKKELEENAQKLQKSEELVKELKRQVIENTTNASERNSKRLETKDKEINLLKNDIIELKNKINSLEKDSKLEDNNLREYYTNKIRQIEEESLNEKVKLEREIFMLKSERDTLIESNKHDINFWKSKCNSLEKQNEALLSQENEGFSSVNLKLNQRLKELDELLNQNNTLKKDNMELTRKLSKSQILNEEYKVELRKAVADLDMATKEYQKSKDFTKIRGSDDSNFELDNMRKNLLIMKTKYNNIKKDYLTKLSELQEENLQLEKKLSMNQPTSRSSDNAAAVQQDRIDYYRLKYHNEVKSNNDLKVMNEYLNRVLMAGSQQIRLDLLKLKEEMNLNDYNYSNFPNRDYYNSRNPYESAYDFRFVNNSHNIFENRHRKKFKTIALLVKACVRMKNTAIKRRWDEQRINYLQRKIAVDDNRITW
What is the function of this protein?
Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication.  Potential role in cross-linking filaments or anchoring other molecules.  It is essential for growth (By similarity).
What are the official names of this protein?
Spindle pole body component 110, Spindle pole body spacer protein SPC110.
What is the protein family that this protein belongs to?
Belongs to the SPC110 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Tightly associated with the nucleus. It is present in a granular pattern that excludes the nucleolus.
Protein: RT24_HUMAN
Sequence: MAASVCSGLLGPRVLSWSRELPCAWRALHTSPVCAKNRAARVRVSKGDKPVTYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAERTVEDVFLRKFMWGTFPGCLADQLVLKRRGNQLEICAVVLRQLSPHKYYFLVGYSETLLSYFYKCPVRLHLQTVPSKVVYKYL
What are the official names of this protein?
28S ribosomal protein S24, mitochondrial, MRP-S24, S24mt, Mitochondrial small ribosomal subunit protein uS3m, bMRP-47, bMRP47.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DCUB_ECOLI
Sequence: MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQPGKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTILCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLGNVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREYVYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMFMLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLGEMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL
What is the function of this protein?
In addition, possesses a regulatory function, which is independent from the transport function, and is required for the response of the DcuS/DcuR two-component system to C4-dicarboxylates (PubMed:18957436, PubMed:27318186).  DcuB interacts physically with DcuS and converts DcuS to the C4-dicarboxylate responsive form (PubMed:27318186).  However, the site for C4-dicarboxylate perception and specificity in sensing by DcuB/DcuS is located on DcuS and not on DcuB (PubMed:27318186).
What are the official names of this protein?
Anaerobic C4-dicarboxylate transporter DcuB.
What is the protein family that this protein belongs to?
Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_TRIPB
Sequence: MTNIRKSHPLIKIINHSFIDLPTPSNISAWWNFGSLLGVCLALQIITGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYAHANGASMFFIFLYFHIGRGIYYGSYNFMETWNIGVILLFLVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPMLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDILGVLLMLLTLLSLILFSPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILMLFPALHMSKQRSMLFRPVSQCLLWILVANLIILTWIGGQPVEYPFITIGQMASISYFCIILILMPTTSFMENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y519_PASMU
Sequence: MALGWYELKLAKDGQFMFNLKAANSQVILTSELYRSRSAAENGIASVQKNGLDEKNFEVRVAKNDKPYFVLKAKNHQEIGRSQYYSSSVSAKKGIVSVTKNAASTVIKDLTNEA
What are the official names of this protein?
UPF0339 protein PM0519.
What is the protein family that this protein belongs to?
Belongs to the UPF0339 family. Duplicated subfamily.
Protein: FIL1_ANTMA
Sequence: MAAMKSIVPLVMLTVLVAQSQLITQSEAQTCSASLANLNACAPFVVLGAATTPSSDCCTALQSVDHECLCNTLRIASRVPAQCNLPPLSCGGKLSWTNC
What are the official names of this protein?
Stamen-specific protein FIL1.
What is the protein family that this protein belongs to?
Belongs to the A9/FIL1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: COAD_PSEPG
Sequence: MNRVLYPGTFDPITKGHGDLVERASRLFDHVIIAVAASPKKNPLFPLEQRVALAREVTKHLPNVEVIGFSSLLAHFAKEQGANVFLRGLRAVSDFEYEFQLANMNRQLAPDVESLFLTPSERYSFISSTLVREIAALGGDITKFVHPVVADALTERFKK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_STRZT
Sequence: MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKARHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEELIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSHQDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLLEHYQLTVEEEKMLAEIKENKE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_ACIF2
Sequence: MTTEPGDRAWVLHHYPYGDTSLIVELFTRTQGRLGVLAKGARRARSALARIEAGRPLWVRWLGRGELPVLAQAEELGPFLPLNPLQNLSLFYVNELLLRLTQRRDPFPDLFQVYEETIDALCSEPGEGWYLRRFERRLLENLGWAPDLAHCAECGRSPDAASSEHWLYQAAHGVFCRAHAPDAAVAIEAAALVWLRGAMQTRSMPVWNSSLRRCLEQELLVHLGGRPLESRRLLTAYLRRTQPAMTIQKREEHSE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SYP1_BACCZ
Sequence: MKQSMVFSPTLREVPADAEIKSHQLLLRAGFMRQNASGIYSFLPFGLKVLHKVERIVREEMERAGAVELLMPAMQAAELWQESGRWYSYGSELMRMKDRNAREFALGATHEEVITDLVRDEVKSYKKLPLTLYQIQTKFRDEQRPRFGLLRGREFLMKDAYSFHATQESLDEVYDRLYKAYSNIFARCGLNFRAVIADSGAMGGKDTHEFMVLSDVGEDTIAYSDTSDYAANIEMAPVVATYTKSDEAEKELEKVATPDQKAIEEVSAFLNIEADKCIKSMVFKVDEKLVVVLVRGDHEVNDVKVKNVYGASVVELASHEEVKELLNCEVGSLGPIGVNGDIEIIADHAVASIVNGCSGANEEGFHYVNVNPERDFKVSQYTDLRFIQEGDQSPDGNGTILFARGIEVGHVFKLGTRYSEAMNATFLDENGKTQPLIMGCYGIGVSRTVAAIAEQFNDENGLVWPKAVAPFHVHVIPVNMKSDAQREMGENIYNSLQEQGYEVLLDDRAERAGVKFADADLFGLPVRVTVGKKADEGIVEVKVRATGESEEIKVEELQTYIANILK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase 1, Prolyl-tRNA synthetase 1, ProRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_EQUHE
Sequence: MVLSAADKTNVKAAWSKVGGNAGDFGAEALERMFLGFPTTKTYFPHFDLSHGSAQVKAHGKKVGDALTLAVGHLDDLPGALSNLSDLHAHKLRVDPVNFKLLSHCLLSTLAVHLPNDFTPAVHASLDKFLSTVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1/2, Alpha-1/2-globin, Hemoglobin alpha-1/2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TVBJ1_HUMAN
Sequence: MGTRLFFYVALCLLWAGHRDAEITQSPRHKITETGRQVTLACHQTWNHNNMFWYRQDLGHGLRLIHYSYGVHDTNKGEVSDGYSVSRSNTEDLPLTLESAASSQTSVYFCASSE
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 10-1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: Y536_LIMRD
Sequence: MSKQENNEDMITLIDENGNEQLFKELFTFDSDDYGKSYIFIYPAEQENDDSVDIQAYIIADNEDNDGQDLVPIEDDKEWDMVEEVLNTFLDNDGNFKA
What are the official names of this protein?
UPF0473 protein Lreu_0536.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: COAD_PSECP
Sequence: MRRAVCPGSFDPIHNGHLEVIARAAGLFDEVIVAISTNYAKKYRFSLDERLEMARETLASLKGIVVEPVGEGLLAEYCRQRGVSAIVKGLRSSSDFDYELPMATMNRQLSGVETVFLPAEAHYIHLSSTLIKEVAGLGGNVSEYVPRSVLRRLLAGEPSANQQPRR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.