PharMolix/UniProtQA huggingface dataset:
Protein: SKIT5_MOUSE
Sequence: MGAVGIPLTAHCVVLFLLQMVALSSEQFTVNGLESPVLVPLDGNLELSCQLSPPQQAKHMEIRWFKNRYSEPVYLYRNGKDLFGEIVYKYVERTELLKDDIGKGKVTLRIFKVTSVDSGSYHCFFKDGKFYEEHIIDVKVTATSSDIQILMHPPNIKGVRLECHSGGWFPQPHMEWRDSKGEYIPATSKSHSQDENEFFNMTMDLFIKSNSHWSATCYIQNFVTHQEESISIVLPGVWDSWCPAWIMITLLIVIHMTYYIKLYRTYATKEMLLKSIQSSSQSSTVDTEKKEWLLKSIQSRIQSSSVDAEKKEWLLKFIQSSIQSSSVDLEKKEWLLKSIQSSIQSAIVDRGTKEWLLESIQSSILSSIVDQGTKVLLLKSIQSSIQSSTLDIETKELLLKSIQSSIQSSIMDLGTKELLLKIIQSSIQSSSVDLGTKELLLKIIQSSIQSSTVDLGTKELLLKIIQSSIQSSSVDLGTKELLLKIIQSSIQSSTVDLGTKELLLKIIQSSIQSSSVDLGAKMGLLESILSSIQSSNVDLETKVLLLKSIQSSIQSSTVYLGIKQWLLERIESIIQSSSVYLDTKELLLKIIQSSIESYSVDLGNKEFLLKIILSSIQSSSVDLGTKELLVKFFQSNIQSSSVIPGTKKLLVKIIQSSLQSSSVDLGTKKVLLDIIQTSIQNSNVHTERKGLLLKIIQSSVQSSSVDQGTKEMLLEIIQSSIQNSSVNQWTKDLLLKIIQSIIQSSSVDLGTKGFLLKIIQSSIQSSSVDIGTKSMLLKKTGLILKSSIVNPGTELLFQLIESIRHSSSVNSETKKMLSEITQSTVQSSSVNPVTEEMIEEKYQLLLQSSSVNLEAENILNVTTQWILQISSVNQGKEMLLLDKIQQILQISSVNPETKDLLLEKIELILQNPGVHQETKDLLLERIQLILQNSSVQKETKYLLLERIRSILQSSCVQKETKDLLLERIQSLLQSSCVQKETKDLLLEKIQLILQNSTVHQETKDLLLERIQLFLQNSTVDQETSYLLLKRIQLILQSSSVKKETKEFVLYIIESILHSSSVHQETKDLLFDRVQLILESSSVQQGLKCLLLNMIQVIFQRTSVQKEMKDLLFNRIPLILESSSVQQETKDKLLDIIQSILQRTSVQEETKDKLLDIIQSILQRSSVQKDTIDTLLDRIQLILQRTSVQKEMKDFLLDRIKSILESFSVHQETKKLLLNRIMSILESSTVHQETKKLLLERIQSILESSSVQQETKKLLLDRIHSILKSSSVQKETKNLLLDRIHSILKSSSVQKESCNKRNPFWKKYALDLGISVFTIIVVTLIMHLKQREADQHFELNTLWSKDTSVILCVLIMFNNRLKALIYFRLYGFSPPGKAHKYIVNYILRFSHPVFCIVYSATILYMYLQIQNKDSLFSLYNSWMVEMEMVLIFLLVIFNVKNIATVLLYFDSTTLRLFFWIKG
What is the function of this protein?
May act by engaging a cell surface molecule on immature T-cells in the embryonic thymus.
What are the official names of this protein?
Selection and upkeep of intraepithelial T-cells protein 5, Skint-5.
What is the protein family that this protein belongs to?
Belongs to the SKINT family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SSRP_CERSK
Sequence: MAKHSDPNSKLIAENRRARFDYFIEEEIEAGIMLLGSEVKSLRQGGSNIGESYASVEEGELWLINGYIAPYLQAKTWGHEERRKRKLLVSRRELARLWTATAREGMTIVPIRMYFNDRGIVKLKIGIAKGKKLSDKRETSAKRDWSREKQRLLKQNS
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GMP_LOTGI
Sequence: MKTAVVLAAFSALMALARAQSPLASMGGGGSPMGMGMGMGMNRMMLPMLMGGMDMKHFALMNMLGGGGGMGGSRMLPLMAALRGNENMLPILLAAKGGMSNPLAMMAMLGGNDNLMNMLPLMMSSGMGMGGGGGMMRGAGAAGGGAAGPGM
What are the official names of this protein?
Glycine and methionine-rich protein, Uncharacterized shell protein 11, LUSP-11.
What are the subcellular locations of this protein?
Secreted.
Protein: CB092_HUMAN
Sequence: MSRAMALFFVLCWIQDEIVLQVFSKVPYDPSFDETRTAVRSITKRDTQKSYSQQKSLNNAAFASGSNEREEHLAKIFDEILLQVFPKFPYDPSFNEATAVRSITKTDMRKGTSIAWNSPKPEYFLGSVDKIPDKDHLSEEKNFKESCLFDRDLREQLTTIDKETLQGAAKPDAHFRTMPCGQLLHFLQRNTIIAAVSGVAILMAIVLLLLGLASYIRKKQPSSPLANTTYNIFIMDGKTWWHNSEEKNFTKLAKKQKQLKSSSCV
What are the official names of this protein?
Uncharacterized protein C2orf92, Long intergenic non-protein coding RNA 1125.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GLND_SHEON
Sequence: MNTALLAKQSLIEQNQTLLARFKAKTPIEELVTQRCQFVDSLVKQAWQQHGLDQYPIALIAVGGYGRGELHPHSDVDLLFLFEGELSKAAETTLSEFIAFLWDANLEIGHSVRTLDDTLRLGRDDITIATNLLEARLLTGPETLFDQLYDAIRQSDFWTSSNFFIAKRDEQTARHAKASAFDLEPNIKSCPGGLRDIQTIAWVAMRHFGASRLEELVEYEFLEPAELEELLECQHFLWKLRFALHMAVGRDENRLLFDVQRQVAELMGYEDATQLAVEQMMKRYYRTVRRVMELNEMLLQLFKRATLGHTKALEIQAIDDNYQRRGAFIEALSDDLFDSGEEIVRLFVHIAKNSNIKGIYAPTLRSLRRARRAQLQPLQENPLCRQAFMEILKHPRGIAALSLMHKHGVLSAYLPAWRNIEGQMQFDLFHAYTVDEHTHRLLLNIERFSQPEQKEEFPLGSVLINQLPKKGLLVLGAIFHDIAKGRGGDHSKLGSSDALAFCKLHGLNDHDGRLVAWLVENHLVMSVTAQRRDISDPDVVADFASKVRDAVHLSYLYCLTVADICATNEKTWNNWKGSLLRDLYFSTQRVLARGKEKPVDIRARVREYQAKAKKELLRRGIKEKDLDTLWQRFKADYFLRHQPNQVAWHAEAILKHKQVDEPLVLVSKHTTRGGTELFVYCQDRPKLFATVMAVLDNKNINVHDANIMTSKDNYALDTFVILEQDGEPVSQLSRIQSIRKALEKALASDNPKLPRFRKLSRKMKPFNVPTQVSFLESNRHGTSMMELIALDTPGLLAKVGDIFYRCNTTLLSAKITTIGERAEDFFILQTNDGLQLNETQEHTLKEALISALSAINTESTN
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: Y1073_HAEIN
Sequence: MKNKYLTLVALSGFFCVALGAFAAHGLSHILEAKALSWIDTGLEYQMFHTIAVLAVALSALRDNKFARLSMSSWLIGILLFSGSLYALAFEASNVIVWITPIGGTLFLIGWISLAYGSFKSKSL
What are the official names of this protein?
UPF0382 membrane protein HI_1073.
What is the protein family that this protein belongs to?
Belongs to the UPF0382 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PQQC_ACIBY
Sequence: MTQTPEALTTEQFKQAIIDKGQYYHIYHPFHVMMYEGKATQQQIQAWVANRYYYQINIPLKDAAIMANCPDQRVRQEWIQRMIDQDGEYPDGGGREAWLRLAEAVGLSREQVISEELVLPGVRFAVDAYVNFARRASWREAASSSLTELFAPQIHQSRLESWPQHYPWIDDKGYEYFRSRLSQARRDVEHGLTITLDSFTTHEQQQRMLEILQFKLDILWSILDALTLAYVHNEAPYHSVTQERVWHKGLFK
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: LEUC_CUPNE
Sequence: EFGGSAVRSLPVEARLTLCNLAVEFSAFSGIVAPDDTVFEYLAGRPYAPAGAQWEPALWHWRSLYSDADAVFDRELSVDCRQLAPMVTWGTSPQHGVAVDGAVPNPAMAIDADTRQAMERALSYMDLRPGQRMADIAIDAAFIGSCTNSRLSDLRSAAGVLAGRKVAPGVTAICVPVSSAVKRAAEAEGLDRVFREAGFEWRESGCSMCFYAGGESFGHRQRVISSTNRNFESRQGPQTRTHLAGPATVAASAVLGRIADPRRPPGA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CXA5_CANLF
Sequence: MGDWSFLGEFLEEVHKHSTVIGKVWLTVLFIFRMLVLGTAAESSWGDEQADFQCDTMQPGCGNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEARGAGSYEYPVAEKAELSCWEEVNGRIVLQGTLLNTYVCSILIRTTMEVAFIVGQYLLYGIFLDTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLFLSLAELYHLGWKKLRQRFVKSGQGMAECQLPGPSAGIVQNCTPPPDFNQCLENGPGGKFFNPFSNKMASQQNTDNLATEQVQGQEPIPGEGFIHIRYAQKPEVPNGASPGHRLPHGYQSDKRRLSKASSKARSDDLSV
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction alpha-5 protein, Connexin-40, Cx40.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: RS6_BRADU
Sequence: MALYEHVFLARQDASPQQVEELTAQMTGIVEGLGGKVTKTENWGVRSLTYRMNKNRKAHFVLLNIDAPSAAIAEIERQERISEDVIRYLSVRVEELEEGPSAMMRKADRDRERDDRGGGFRGEREGGFRGDREGGFRGGDRDGGGFRGDRGPRRPREEAETATDGE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RPOE_LISMO
Sequence: MDLKNLTQEERSELSLIDVAHFILEQRKETILFPELVKEIQAFLGLKDAEIRERLVQFYTDMNIDGNFISLGNNTWGLRAWYPMDAIDEEVQTQTTPKKKRKSDDDEDEDEEILDDDVDYDDEEIVEELGEEEISLADVLLDEDEDDDDHLPDGIEGDLATVEDDYTDGDYTEDPEDK
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: DOHH_CHAGB
Sequence: MTAPTTTSPSSEATTTTTTTTLNTIATLHQSLTTETTPLPVRFRALFSLKHVAATHPATSAESLAAIDAIAAGFASPSALLKHELAYCLGQTANGAAIPYLTAVLEDTGEDAMCRHEAAEALGALGDVASLGVLKRFRDREGEEVVVTETCELAVERIEWENGEGKKAEKLRASDFSSVDPAPPTAQGQEEQTVEELGNALMDTSLPLFKRYRAMFALRDLASPPDLPTAVPAVLALAKGFADSSALFRHEIAFVFGQLAHPASIPALTEALSNTEEASMVRHEAAEALGSLGDEEGVEETLRKFLHDAEAVVRESVIVALDMAEYEKSNETEYALIPEAQGTA
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRB_BORPA
Sequence: MLNPQLNRHGELIHLLSTEGLPRRIIEQILDLAATFVPAPGQEFPKLPLLHGKSVFNLFFENSTRTRTTFEIAAKRLSADVVNLNIAASSTSKGESLLDTIANLSAMQAGLFVVRHGASGAPYLIAQHVAPHVHVINAGDGRHAHPTQALLDMYTIRHHKGDFNQLTVAIVGDVLHSRVARSDIHALTTLGVPEVRVVAPATLLPEGLAQMGVRVCTDMEEGLRDADVVIMLRLQNERMRGALLPSAHEYFKHYGLTQARLALARPDAIVMHPGPMNRGVEIASEVADSGQAVILDQVTFGIAVRMAAMSLVAGVRP
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: LGT_RICPR
Sequence: MLNELNNLFMILPNINPIIFSIGPFSISWYSLAYVVGILLGWFYATKIIEKFKPEITKKHIDDFITYAIIAIIVGGRLGYVLLYNPLKYFTNPIEILKTYEGGMSFHGATIGIIMAAYLFCQKYKINFLSLTDIITTVAPIGLFLGRIANFINCELYGRITNSSFGIIFPNSDLQPRHPSQLYEAFFEGLILFCILTYAVFRHDTLKKRGLNSGIYLIFYSLFRIIIEMFREPDIQIGFILDSLTMGQILSAPMLLLGSYLICRSNPK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DHDDS_HUMAN
Sequence: MSWIKEGELSLWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEEKEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNHSVLQKARDMYAEERKRQQLERDQATVTEQLLREGLQASGDAQLRRTRLHKLSARREERVQGFLQALELKRADWLARLGTASA
What is the function of this protein?
With NUS1, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery.  Both subunits contribute to enzymatic activity, i. e.  condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:25066056, PubMed:28842490, PubMed:32817466).  Synthesizes long-chain polyprenols, mostly of C95 and C100 chain length (PubMed:32817466).  Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol (PubMed:21572394).
What are the official names of this protein?
Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Cis-isoprenyltransferase, CIT, Cis-IPTase, Cis-prenyltransferase subunit hCIT, Epididymis tissue protein Li 189m.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Note=colocalizes with calnexin.
Protein: RL39_AERPE
Sequence: MARNKPLGRKLRLARALKSNRAIPVWVVIRTSRRIRFNLLRRHWRRSKLKV
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: PEPT_AERHH
Sequence: MDTLLERFLRYVTFHTRSDATNPACPSSEGQLVFARALCDEMQQMGLSRVTLDEYGYLTACLPGNQPDAPAIGLIAHMDTADYEAAHVVPQIIENYQGGDICLGKGDEVLAIRDYRFLKNYLGQDLITTDGSTLLGADDKAGIAEILTAIDHLLAHPEIPRGDVWVGFTPDEEIGRGADRFPLDRFPAKWAYTVDGGELGELEYENFNAAGATVRFIGNNVHPGTAKGSMINSQTLAARFHAAMPTEQTPEATDGYQGFFHLAQMNGTVEETCLHYIIRDFDDEGFAARKAQLKERVASLQLEAPRARIELTLTDSYRNMRSQIEPHMHIVELAKAAMQAADVTPRIKPIRGGTDGARLSFMGLPCPNLFTGGHNFHGKHEFIPLQSMEKAVTTLVELVRLTSAWRG
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_LACLA
Sequence: MRYFTAGESHGPRLTAIIEGVPAGLSLSAEDINIELKRRQGGYGRGGRMKIESDQVEITSGVRHGKTIGSPITLNVTNRDFKNWEQIMAAQDVEDKIKKQRRLTKPRPGHADLVGGMKYEFEDLRNVLERSSARETTMRVAVGAVAKKLLHELEIEIANHVVNFGGREITSPENLSVQDIRQTAGLSDLSIFDESQAEELRNYIDQIKKAGDTIGGIIETRVEGVPAGLGSYVQYDRKLDAKIAAAVVSINAFKGVEFGLGFEAGKRPGSQVMDEIIWSEDKGYTRSSNQLGGFEGGMTNGEQVIVRGVMKPIPTLYKPLMSIDIESHEPYKASVERSDPTALPAAGVVMENVVATVVAQEICDKFDSDTMNELRDAVASYKKRLSEY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RLME_ECO8A
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIRL8_ARATH
Sequence: MMGYEQMNQMTMTTTAMMKNYNKKGLINTPQKKMTRRSVSAIDGGAAATAKEGDRRQNIKTLDLSGMSLASLSASSINLASISKLDLSNNNIQKIPESLVARMLNLWALDLQSNQLKTLPNSIGCLSKLKFLNVSGNYLQSLPKTIEDCRSLEELNANFNELTRLPDAIGFELTNLTKLSVNSNKLVLLPNSVSYLTSLRVLDARLNRLSSLPEDLENLVNLQVLNVSQNFQHLTTLPYSVGLLISLVELDVSYNGITVLPDSLGCLRRIQKLSVEGNPLISPPFEVVEQGLEALKQYMSEKMTESYKKTPTKKKSWGIGKLVKYGLSSSPGRSTGREDGKEGFINVSDYRQIDGIASPRHVSLFNPRRLLSPLSAYFSPPRY
What is the function of this protein?
Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction.
What are the official names of this protein?
Plant intracellular Ras-group-related LRR protein 8.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
Protein: G6PI_SALTI
Sequence: MKNINPTQTSAWQALQKHYDEMKDVTIAELFANDSDRFAKFSATFDDLMLVDFSKNRITEETLAKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHVALRNRSNTPIIVDGKDVMPEVNAVLEKMKTFSQAIISGQWKGYTGKAITDVVNIGIGGSDLGPFMVTEALRPYKNHLTMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKSAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIILSVGFDNFVELLSGAHAMDKHFSTTPAEKNLPILLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNAVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPAQLEHVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELGDDKAISSHDSSTNGLINRYKAWRA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CILK1_HUMAN
Sequence: MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDSEKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDHPSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWADLDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRDTPTLRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNSVGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYSSLKAMRPHPGRPFFHTQPRSTPGLIPRPPAAQPVHGRTDWASKYASRR
What is the function of this protein?
Required for ciliogenesis (PubMed:24797473).  Phosphorylates KIF3A (By similarity).  Involved in the control of ciliary length (PubMed:24853502).  Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity).  May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity).  Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase ICK, Ciliogenesis associated kinase 1, Intestinal cell kinase, hICK, Laryngeal cancer kinase 2, LCK2, MAK-related kinase, MRK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Also found at the ciliary tip (PubMed:24797473). Nuclear localization has been observed with a GFP- tagged construct in transfected HeLa cells (PubMed:12103360, PubMed:19185282). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Note=Predominant cytoplasmic localization has been observed with a N-terminally GFP-tagged construct.
Protein: ROCA_BACAH
Sequence: MVVAYKHEPFTDFSVEANKLAFEEGLKKVESYLGQDYPLIIGGEKITTEDKIVSVNPANKEELVGRVSKASRELAEKAMQVADETFQTWRKSKPEMRADILFRAAAIVRRRKHEFSAILVKEAGKPWNEADADTAEAIDFMEYYGRQMLKLKDGIPVESRPIEYNRFSYIPLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGVVNFVPGNGSEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGKDTIVVDKEADLELAAKSIVASAFGFSGQKCSACSRAVIHEDVYDHVLNRAVELTKELTVANPAVLGTNMGPVNDQAAFDKVMSYVAIGKEEGRILAGGEGDDSKGWFIQPTIVADVAEDARLMKEEIFGPVVAFCKAKDFDHALAIANNTEYGLTGAVISNNRDHIEKAREDFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLALHMQAKTTSETL
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: RIMM_STRE4
Sequence: MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDKDRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYHQIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRVDVEIMEGLDDED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_STAAW
Sequence: MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1618_HAEIN
Sequence: MVFSSAKREKNNMLAVNNLCIERNGRAIIQDLSFTLEGQKRLFVQGEIGSGKTTLLLALLGFVPVTKGEIKLFGKVCRKEKDFAPFRGTIGICFQNADDQLFGPTVLDDIAFGPLNQNVPREQAYHIAEQQLERLGITRLKDRMVHTLSGGEKNFTALAGVLAMQPKILLLDEPTNGLDRKNTEKLTALLRELSLPILISSHHHGFINELATEIISL
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein HI_1618.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.