PharMolix/UniProtQA huggingface dataset:
Protein: PKN2_RAT
Sequence: MASNPDRGEILLTELQVDSRPLPFSENVSAVQKLDFSDTIVQQKLDDVKDRIKREIRKELKIKEGAENLRKVTTDKKNLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDYTDCPRTPDTPNSDSRSSTSNNRRLMALQKQLDIELKVKQGAENMIQMYSNGPSKDRKLHGTAQQLLQDNKTKIEVIRMHILQAVLTNELAFDNAKPVISPLELRNGRIIEHHFRIEFAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNELPKNHPKSSVVIEELSLVASPTLSPRQSMLSTQNQYSTLSKPAALTGTLEVRLWGAKISWENVPGRSKATSVALPGWSPSENRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTIWKPISNQSWDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMALYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQTPVPATVPVVDARTPELAPPASDSTVTKLDFDLEPEAPPAPPRASSLGEIDDSSELRVLDIPGQGSETVFDIENDRNNMRPKSKSEYELNIPDSSRSCWSVGELEDKRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKHTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEASVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGAGEKDAEDVKKHPFFRLTDWSALLDKKVKPPFVPTIRGREDVSNFDDEFTSEAPILTPPREPRILLEEEQEMFRDFDYVADWC
What is the function of this protein?
PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell.  Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes.  Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin.  Phosphorylates HDAC5, therefore lead to impair HDAC5 import.  Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells.  Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner.  Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation.  Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion.  Inhibits Akt pro-survival-induced kinase activity.  Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF).  Involved in the negative regulation of ciliogenesis.
What are the official names of this protein?
Serine/threonine-protein kinase N2, Cardiolipin-activated protein kinase Pak2, PKN gamma, Protease-activated kinase 2, PAK-2, Protein kinase C-like 2, Protein-kinase C-related kinase 2, p140 kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane. Cell projection, lamellipodium. Cytoplasm, cytoskeleton. Cleavage furrow. Midbody. Cell junction. Note=Colocalizes with PTPN13 in lamellipodia-like structures, regions of large actin turnover. Accumulates during telophase at the cleavage furrow and concentrates finally around the midbody in cytokinesis. Recruited to nascent cell-cell contacts at the apical surface of cells.
Protein: HSF1_CHICK
Sequence: MEGPGAAAAAVGAGPGGSNVSAFLTKLWTLVEDPETDPLICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPEKDDTEFQHPYFIRGQEHLLENIKRKVTSVSSIKNEDIKVRQDNVTKLLTDIQVMKGKQESMDSKLIAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSSSAHSMPKYSRQYSLEHVHGSSPYAASSPAYSGSNIYSPDSSTNSGPIISDVTELAQSSPSASPSGSLDERSSPVVRIKEEPPSPSRSPKENEPSTTTAAAGNSTEQPQPQEKCLSVACLDKNELNDHLDTIDSNLDNLQTMLSTHGFSVDTTALLDLFSPSMTVTDMNLPDLDSSLASIQDLLSSQEQQKPSEADAAAADTGKQLVHYTAQPLFLVDSSAVDVGSGDLPIFFELGEGSYFTDGDEYNEDPTISLLSGTEQPKPKDPTVS
What is the function of this protein?
Functions as a stress-inducible and DNA-binding transcription factor that plays a central role in the transcriptional activation of the heat shock response (HSR), leading to the expression of a large class of molecular chaperones heat shock proteins (HSPs) that protect cells from cellular insults' damage (PubMed:8455593).  In unstressed cells, is present in a HSP90-containing multichaperone complex that maintains it in a non-DNA-binding inactivated monomeric form.  Upon exposure to heat and other stress stimuli, undergoes homotrimerization and activates HSP gene transcription through binding to site-specific heat shock elements (HSEs) present in the promoter regions of HSP genes.  Upon heat shock stress, forms a chromatin-associated complex with TTC5/STRAP and p300/EP300 to stimulate HSR transcription, therefore increasing cell survival (By similarity).  Activation is reversible, and during the attenuation and recovery phase period of the HSR, returns to its unactivated form.  Binds to inverted 5'-NGAAN-3' pentamer DNA sequences.  Binds to chromatin at heat shock gene promoters.  Also serves several other functions independently of its transcriptional activity.  Involved in the repression of Ras-induced transcriptional activation of the c-fos gene in heat-stressed cells.  Positively regulates pre-mRNA 3'-end processing and polyadenylation of HSP70 mRNA upon heat-stressed cells.  Plays a role in nuclear export of stress-induced mRNA.  Plays a role in the regulation of mitotic progression.  Also plays a role as a negative regulator of non-homologous end joining (NHEJ) repair activity in a DNA damage-dependent manner.  Involved in stress-induced cancer cell proliferation.
What are the official names of this protein?
Heat shock factor protein 1, HSF 1, HSF 3A, HSTF 3A, Heat shock transcription factor 1, HSTF 1.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nucleoplasm. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore.
Protein: QUEA_STAS1
Sequence: MDIEAFDYHLPEALIAQTPLKNRDESRLLILGRQSGYIEHKHFKDVTDYLNEGDTLVLNDTRVMPARLFGMKEETGAKVEMLMLTQIEGNDWEVLLKPAKRIKVGNKLTFGEGKIIAECIEELDQGGRIMRLHYDGILQERLDELGEMPLPPYIKERLDDQERYQTVYAKASGSAAAPTAGLHFTDELLERIKAQGVNIAFITLHVGLGTFRPVSVDNIDDHEMHSEYYQMDEATANLLNSTRDNGNRIISVGTTSTRTLETIMQSSDRFVAKSGWTDIFIFPGFNFKAIDGLITNFHLPKSTLVMLVSAFSSRDYIINAYNQAVASEYRFFSFGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GVPI1_HALSA
Sequence: MSDKQQQKHKQKARQARVKAQINRDKARRNLLRQREKLARRRTRNRKQSEPRRDDSDGDDTDGETVKNPAAHSTMPPQKSNAENAVRNSHSTVPKTPKYSDVTARERLYGQRLHQKTAGGNSEASAPSDESASGSPTEDEVNDE
What is the function of this protein?
May play a structural or regulatory role in gas vesicle synthesis.
What are the official names of this protein?
Protein GvpI 1.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: GGT5_RAT
Sequence: MAWGHRTTVCLVLLGVSLGLAIIVLAVVLPHHQASCRPDAFTRAAVAADSKICSDIGRVILQQQGSPVDAAIAALICTGVVNPQSMGLGGGVVFTIYNASTGKVEVINARETVPASHDQRLLDQCTNALPLCTGAQWIGVPGELRGYAEAHRRYGRLPWAQLFQPTIALLREGFRVPPILSQFLNTSFLQPCLNSSTLRQLFFNGTETLRSQDPLPWPALANTLETVAKEGAEVLYTGKLGQTLVEDIAWQGSQLTVQDLAAFRPKVVEPLEMALGNYTLYSPPPPAGGAILSFILNVLKGFNFSAETVAGPEGKVNMYHHLVEALKFAVGQRWRLWDPYSHPGIQNISQDLLRETLAQHIRQQIDGRGDHQLSHYNLSGVRGNSMGTSHVSVLGEDGSAVAATSTINTPFGAMVYSPRTGILLNNELLDLCWRHKPGSTVTPPPVPGEQPPSSMVPSILINEVQGSKLVIGGAGGELIISAVTQAIVNKLWLGFSLTDAIAAPILHVNSKGHVEYEPKFNQEVRKGLQDRGQSQSQSQRPVFLNSVQAVFQEGPCVYAASDLRKAGKASGY
What is the function of this protein?
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione-S-conjugate.  Converts leukotriene C4 (LTC4), a glutathione-S-conjugate, to leukotriene D4 (LTD4).  Does not cleave gamma-glutamyl compounds such as gamma-glutamyl leucine.  May also catalyze a transpeptidation reaction in addition to the hydrolysis reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound.  Acts as a negative regulator of geranylgeranyl glutathione bioactivity by cleaving off its gamma-glutamyl group, playing a role in adaptive immune responses.
What are the official names of this protein?
Glutathione hydrolase 5 proenzyme, Gamma-glutamyl leukotrienase, GGL, Gamma-glutamyl transpeptidase-related enzyme, GGT-rel, Gamma-glutamyltransferase 5, GGT 5, Gamma-glutamyltransferase-like activity 1, Gamma-glutamyltranspeptidase 5, Leukotriene-C4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein.
Protein: UHPA_ECO57
Sequence: MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW
What is the function of this protein?
Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT.  Activates the transcription of the uhpT gene.  Acts by binding specifically to the uhpT promoter region.
What are the official names of this protein?
Transcriptional regulatory protein UhpA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYF_ACOCL
Sequence: MQNRNTFSWVKEQMTRFISVSIMIYVITRTSIANAYPIFAQQGYENPREATGRIVCANCHLANKPVDIEVPQAVLPDTVFEAVVRIPYDKQLKQVLANGKKGSLNVGAVLILPEGFELAPPDRISPEMKEKMGNLAFQSYRPTKKNIIVIGPVPGQKYSEIVFPILSPDPATKKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATAAGVVSRILRKEKGGYEITIADASDGHQVVDIIPPGPELLVSEGESIKLDQPLTSNPNVGGFGQGDAEIVLQDPLRVQGLLFFLASVILAQIFLVLKKKQFEKVQLYEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CDK7_RAT
Sequence: ANRNEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNWAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLQHIFIAAGDDLLELIQGLFLFNPCTRITASQALRTKYFSNRPGPTPGCQLPRPNCPVEALKEQSNPAMATKRKRAEALEQ
What is the function of this protein?
Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription.  Cyclin-dependent kinases (CDKs) are activated by the binding to a cyclin and mediate the progression through the cell cycle.  Each different complex controls a specific transition between 2 subsequent phases in the cell cycle.  Required for both activation and complex formation of CDK1/cyclin-B during G2-M transition, and for activation of CDK2/cyclins during G1-S transition (but not complex formation).  CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex.  Phosphorylates SPT5/SUPT5H, SF1/NR5A1, POLR2A, p53/TP53, CDK1, CDK2, CDK4, CDK6 and CDK11B/CDK11.  CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation, thus regulating cell cycle progression.  CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts.  Phosphorylation of POLR2A in complex with DNA promotes transcription initiation by triggering dissociation from DNA.  Its expression and activity are constant throughout the cell cycle.  Upon DNA damage, triggers p53/TP53 activation by phosphorylation, but is inactivated in turn by p53/TP53; this feedback loop may lead to an arrest of the cell cycle and of the transcription, helping in cell recovery, or to apoptosis.  Required for DNA-bound peptides-mediated transcription and cellular growth inhibition (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 7, 39 protein kinase, P39 Mo15, CDK-activating kinase 1, Cell division protein kinase 7, TFIIH basal transcription factor complex kinase subunit.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Colocalizes with PRKCI in the cytoplasm and nucleus. Translocates from the nucleus to cytoplasm and perinuclear region in response to DNA-bound peptides (By similarity).
Protein: LEPA_LIGS1
Sequence: MDLEQMKVRQKHIRNFSIVAHIDHGKSTLADRILEMTDTVTKREMQDQLLDSMELERERGITIKLNAVELHYHAKDGETYIFHLIDTPGHVDFSYEVSRSLAACEGAVLVVDAAQGVEAQTLANVYLALDDDLEIVPVINKIDLPSADPERVRQEIEDVIGLDASEAVLASAKKGIGIEEMLEQIVQNVPAPDGDLEAPLKALIFDSVYDDYRGVVLSIRVVEGTVKPGDKIRLMNSGAEYEVVEVGVNSPKPLKRDFLMAGDVGYLTASIKDIQDTRVGDTVTNANNPTAKPLEGYREMNPMVYSGLYPTDNAKYNDLREALEKLQLNDAALEFEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNMDLITTAPSVTYDVELTDGTHINVSNPSEMPETPLIKQINEPYVKAEIMVPNDYVGAVMELCQRKRGTFVTMDYLDDYRVNVIYEIPLSEIIFDFFDKLKSSTRGYASLDYELDGTRPSDLVKIDILLNGDKVDALSFISHRQFAQARGRVIVDKLKTIIPRQNFEIPIQAAIGAKIIARTNIKAYRKDVTARIHTGDPDRRAKLLDKQKRGKKRMKAVGTVDVPQAAFMAVLKTDEEIK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OSA_SHIFL
Sequence: MLMLLRRRCRAWLEIRRLDKELAQSSGLPLELPQIVPNAWNEVVWRLPVPNHPDAFMTASNAAQSDFIVYVNGLAFYRAWLALGVEDSQACPLKQDMPKDRKYPSSAAHFAVGIDSPVPLADVSPTMILGHFAVCFTDGMTRSMWLLAHEVAVFPVLSRDEASAVMLAEHVGVAAPIQVSKLREQCRKI
What is the function of this protein?
Suppression of A. tumefaciens oncogenicity.
What are the official names of this protein?
Protein osa.
Protein: HFQ_YERPS
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNTPSGSTNNYHGSNPSAPQQPQQDSDDAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: DID8A_CERCE
Sequence: MNSAHPCCDPVTCKPKRGEHCISGPCCRNCKFLSPGTICKKARGDDMNDYCTGISSDCPRNRIKK
What is the function of this protein?
Inhibits integrins alpha-IIb/beta-3 (ITGA2B/ITGB3), alpha-V/beta-3 (ITGAV/ITGB3), and alpha-5/beta-1 (ITGA5/ITGB1).
What are the official names of this protein?
Disintegrin CC8A.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KAD_SYNJB
Sequence: MPRLIFLGPPGAGKGTQAERLAAIYHTPKISTGDLLRAEVKAQTPLGCQAKVYMDAGELVPDEVLIGMVKGQLQQSPEQGWILDGFPRTLAQAEALEELLQELGQDYDYVLNLEVPDEVVVARLLARGKEQGRSDDADRSVILKRLEVYRQQTAPLIDFYEAKGRLQRVNGNQPMESVQEHLQALLEGFRRTA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_AQUAE
Sequence: MRIVFGGSFDPVHVGHIILARDVCEHFNAKEVIFVPTYQAPLKEKHKASAQDRLNMLKLALEREEKFTIEDYEIRRKGISYTVYTLKYLKEKYGGEELYLLLGSDSFLKFHKWKEPREILKLAKIIVVEREGMLEKVKEYIKEYFPELRKNEDIFFYKGRRIDISSTE
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RS12_GLOC7
Sequence: MPTIQQLIRTERSKVQKKTKSPALKQCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGTLDATGVKDRKQGRSKYGTKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ASA1_YEAS7
Sequence: MRGFSNEIILKRTLTLSDFTLRYHKRGITALQVIKAPSVSNVPVLLSGDNYGYFVMWDLVTKRPITHIEIEGNSHIIAFWWVETTNVLYILSKDSMLRIFELDSSTQLSIDLVRKLSQANKTDHLQWTKIYEMPINTLNFANFIIEAEVKPTKDNKSYRLVCCHTDDSETIDIYQIIEDSTFKLKRPFNNINFPRFLKQQNFLGISKDSKFGIIMRFAKLNDVIFLGYENGFVVGFKITFDEGLQRDIAELVHVSNDHYPNPILDMCVSGDELYSCSTDDFITKYKIPVNLQLETKYLRDDALLIKCPSSLRVSEPSKVHLPLKNIGHIDKVKDDYLVVSSWSGMTIVYNMRTSEVEQTFVKSKNNLVVSDSSMGDLTNGSGSNTESSSKSHNYKVGAMTCLESFDVQSDGLRLGQLRRIKALAKCNWCLIGYEDGTIKLNKI
What is the function of this protein?
Component of the ASTRA complex involved in chromatin remodeling.
What are the official names of this protein?
ASTRA-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ASA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECU_PEDPA
Sequence: MKFNYPTGSKATTPKMSQAKVSMPPIYGKRGMSLEEELNESNAYYLSHGVAVIHKKPTPIQIVKVDYPKRSAAQIKEAYFSKASTTDYNGVYRGKYIDFDAKETTNSTSFPLSNFHEHQINHMKDCEKVGGICFTIIKFVKLNKIFLLKTKDLFQFWDSKENGGRKSIPLSVFEEQGYQLEYQMNPLIPYLKAVDKIIENL
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHDC_BACAN
Sequence: MSEATTTLDGWYCLHDLRSIDWAAWKTLSSDERGQAVSEFLNVVEKWNDVAAAKKGSHAMYTVVGQKADIMLMILRPTMEELNEIETELNKTTLAEYMVPAYSYVSVVELSNYLPADEDPYQNPQILARLYPELPKANHICFYPMDKRRQGDDNWYMLPMEERKKMMYSHSKIGRQYAGKVRQVISGSVGFDDFEWGVTLFADDVLQFKKLIYEMRFDEVSARYGEFGTFFVGNILPDEKVEKFLHI
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: CLPP_SODGM
Sequence: MALVPMVVEQTSRGERSYDIFSRLLKERIIFMTGQVEDHMANLIVAQMMFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTFCMGQAASMGAFLLAAGAKGKRFCLPNSRVMIHQPLGGFQGQATDIEIHAREILKVKARMNELMAKHTGQPLEVIERDTERDRFLSAPEAVDYGLVDSVLSQRT
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_CLOB8
Sequence: MKSKRHTKILEIIGSREIETQEELADALKKEGFDVTQATVSRDIKNLKLIKMQSTNGKSKYAVSTGEQKNIIDRLSNILANTVLSVENVDKMVVIKTITGSAPITAEAIDNLESADIAGTVAGDNTIFILVRSLESAEDLVDKIRKRMSS
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLYL_DICCH
Sequence: MKYLNCFISTGLAAFFLVNSTSVLAADCSSDLTSGISTKRIYYVAPNGSSSNNGNSFNSPMSFTAAMAAANPGELILLKPGTYTIPYTQGKGNTITFNKSGKEGSPIYVAAANCGRAVFDFSFPDSQWVQASYGFYVTGDYWYFKGIEVTRAGYQGAYVTGSHNTFENTAFHHNRNTGLEINNGGSYNTVINSDAYRNYDPKKNGSMADGFGPKQKQGQGNRFGGCRAWENSDDGFDLFDSPQKVVIENSWAFRNGINYWSDSSFAGNGNGFKLGGNQAVGNHRITRSVAFGNVSKGFDQNNNAGGVTVINNTSYKNGINYGFGSNVKSGQKHYFRNNVSLSGSATVNNADAKSNSWDTGPVASASDFVSLDTSLATISRDNDGTLPETALFRLSTNSKLINAGTKESNISYSGSAPDLGAFERN
What is the function of this protein?
Presents an endo-cleaving activity on polygalacturonate or partially methylated pectin.
What are the official names of this protein?
Pectate lyase L, Pectate transeliminase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 9 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASTD_SALHS
Sequence: MTLWINGDWITGQGERRRKTNPVSGEILWQGNDANAAQVAEACQAARAAFPRWARQPFAARQAIVEKFAVLLEAHKAELTEVIARETGKPRWEAATEVTAMINKIAISIKAYHARTGEQKSELVDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTLIFKPSELTPWTGETVIKLWERAGLPAGVLNLVQGGRETGQALSSLDDLDGLLFTGSASTGYQLHRQLSGQPEKILALEMGGNNPLIIEDVANIDAAVHLTLQSAFITAGQRCTCARRLLVKQGAQGDAFLARLVDVAGRLQPGRWDDDPQSFIGGLISAQAAQHVMEAWRQREALGGRTLLAPRKVKEGTSLLTPGIIELTGVADVPDEEVFGPLLNVWRYAHFDEAIRLANNTRFGLSCGLVSTDRAQFEQLLLEARAGIVNWNKPLTGAASTAPFGGVGASGNHRPSAWYAADYCAWPMASLESPELTLPATLSPGLDFSRREAV
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.