PharMolix/UniProtQA huggingface dataset:
Protein: SYR_HELPS
Sequence: MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTHEKTQGLFDSVVACKGYINFTLSLDFLERFTQKALELKEKFGSQPKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLKESVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDALGIHFDSYASEREVFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLAGDIVYHDEKFKQNYTKYINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLTDLNAEEKYLLFSALSLPKIIESSFEEYGLQKMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLSNAFKLLGIEIKTKISAKD
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3061_HALSA
Sequence: MSADYDITETLDVKGASCPMPVVKTKSAIDDLAEGEILEVLATDSGSMSDIDGWASGTAGVELVDQEEGDDVYKHYVRKTK
What are the official names of this protein?
Putative sulfur carrier protein VNG_5061C/VNG_5236C/VNG_6059C/VNG_6467C.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
Protein: ITR2_SECED
Sequence: EEDRKCPKILMRCKRDSDCLAKCTCQESGYCG
What is the function of this protein?
Inhibits trypsin.
What are the official names of this protein?
Trypsin inhibitor 2b, SETI-IIb, Trypsin inhibitor IIb.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GM_HHV8P
Sequence: MRASKSDRFLMSSWVKLLFVAVIMYICSAVVPMAATYEGLGFPCYFNNLVNYSALNLTVRNSAKHLTPTLFLEKPEMLVYIFWTFIVDGIAIVYYCLAAVAVYRAKHVHATTMMSMQSWIALLGSHSVLYVAILRMWSMQLFIHVLSYKHVLMAAFVYCIHFCISFAHIQSLITCNSAQWEIPLLEQHVPDNTMMESLLTRWKPVCVNLYLSTTALEMLLFSLSTMMAVGNSFYVLVSDAIFGAVNMFLALTVVWYINTEFFLVKFMRRQVGFYVGVFVGYLILLLPVIRYENAFVQANLHYIVAINISCIPILCILAIVIRVIRSDWGLCTPSAAYMPLATSAPTVDRTPTVHQKPPPLPAKTRARAKVKDISTPAPRTQYQSDHESDSEIDETQMIFI
What is the function of this protein?
Envelope glycoprotein important for virion assembly and egress.  Plays a role in the correct incorporation of gH-gL into virion membrane.  Directs the glycoprotein N (gN) to the host trans-Golgi network.
What are the official names of this protein?
Envelope glycoprotein M, gM.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein M family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network. Host endosome membrane; Multi-pass membrane protein. Host nucleus inner membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein accumulates in the trans-Golgi network where secondary envelopment occurs.
Protein: RU2A_ARATH
Sequence: MVKLTADLIWKSPHFFNAIKERELDLRGNKIPVIENLGATEDQFDTIDLSDNEIVKLENFPYLNRLGTLLINNNRITRINPNLGEFLPKLHSLVLTNNRLVNLVEIDPLASIPKLQYLSLLDNNITKKANYRLYVIHKLKSLRVLDFIKIKAKERAEAASLFSSKEAEEEVKKVSREEVKKVSETAENPETPKVVAPTAEQILAIKAAIINSQTIEEIARLEQALKFGQVPAGLIIPDPATNDSAPMEE
What is the function of this protein?
This protein is associated with sn-RNP U2.  It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity).
What are the official names of this protein?
U2 small nuclear ribonucleoprotein A', U2 snRNP A'.
What is the protein family that this protein belongs to?
Belongs to the U2 small nuclear ribonucleoprotein A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPA1_LEGPA
Sequence: MNWSNTPSFLEKQRQRLERYQFQIKVSEQGRVVSVGDGIIWIKGLPGAAIDEILISEDECCIAMVFHLTEELVGAVMLVQTKKLKAGTPIFPLKRVLSIPVGDKLLGRVIDPLGHPLDGGEIPPHEEQGLLDRLSPPILHRDFVNRPLYTGNKMLDNLIPIGKGQRELLIGDNGLGKSALALDIVMNQKDKKVYCVYVLIGQKRSTVSSTIQLLKEANALDYTTVVVAQATALPGLLYLAPFAGCAIAEHWMKKGLDALVIYDDLSAHANSYRELSLLLRRPPGREAFPADIFYLHSRLLERSTCLSPALGGGSMTALPIIETKEGEMATYIPTNLISITDGQIFFDESLFSSGFLPAIDITKSVSRVGGKAQHPQIKKESGRMKLDYLQFLDLELFTRFGAKLDAKMQKQIQKGRVLREILKQERFSPLPIEFQLAWLIAYNEGFFDELNLEDIPKMLKKIEEEIKQSTLSLGSPREQWKKAIKEWLMA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PANC_HELP2
Sequence: MRVLETIAVLREYRKSLKESVGFVPTMGALHRGHQSLIERSLKENSHTIVSVFVNPTQFGANEDFSAYPRPLEKDLALCEKLGVSAVFVPKVSEMYPYEIEQRLKLYAPTFLSHSLEGAVRHGHFDGVVQVVLRLFHLVNPTRAYFGKKDAQQLLIIEHLVKDLLLDIEIAPCEIARDSDHLALSSRNVYLNATERKQALAIPKALENIKQAIDKGEKACEKLKKLGLEILETLEVDYLEFCNHKLEPLKTIEPANTLVLVAARVGKTRLLDNLWV
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_ARAHI
Sequence: MSRYRGPRFKKIRRLGALPGLTSKRPRAGSDLRNQSRSGKKSQYRIRLEEKQKLRFHYGLTERQLLKYVRIAGKAKGSTGQVLLQLLEMRLDNILFRLGMALTIPQARQLVNHGHILVNGRIVDIPSYRCKPRDIITVKDEQNSRTLVQNLLDSSAPEELPNHLTLHTFQYEGLVNQIIDRKCVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS11A_YEAST
Sequence: MSTELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S11-A, RP41, S18, Small ribosomal subunit protein uS17-A, YS12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THPS_BOVIN
Sequence: PEFLEDPSVLTKEKLKSELVANNVTLPAGEQRKEVYVELYLQHLTALKR
What is the function of this protein?
Hormone of the spleen with pleiotropic actions on prothymocytes, mature T-cells, the nicotinic acetylcholine receptor, and pituitary corticotrophs.
What are the official names of this protein?
Splenin, Thymopoietin III.
What is the protein family that this protein belongs to?
Belongs to the thymopoietin family.
Protein: RAP2B_HUMAN
Sequence: MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSACVIL
What is the function of this protein?
Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.  Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1.  May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK.  May regulate membrane vesiculation in red blood cells.
What are the official names of this protein?
Ras-related protein Rap-2b.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Note=Associated with red blood cells- released vesicles.
Protein: EAF7_YARLI
Sequence: MVKREDTDDTSTQAVDGAEVESNGQGDAGTDSSPWSIESETVLFNSLCKFKPVGIHKHFRMISLSASLNYYFSESPKDAPVFSHQDVWDKLGTLYDLDGLDELEYVADNQDSDMDEDEDDEAAIEGIAKRSQMKEFVLPFRDYGFLQIEQATAVASEQSSPAMSREQSVLEDGPTAGDEKKGLADDDDESSDLDELDDEEMKLAETKIKVEGEQQEREENGGEEEHDTMEGSAEPEEAEKSEEEGEGEESGESESESGSESQSDSDAQTGRQRRTRAATAAAVRGRGTSKGKTVRDKKSSPSTRASSAPRRSTRRKATTEPEDTATEREETPTPKKSSGGVKKPAPRRSTRRKK
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF7.
What is the protein family that this protein belongs to?
Belongs to the EAF7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR15_SACHY
Sequence: MVKEEKQENRGSVEFQVFSFTNKIRRLASHLELHKKDFSSERGLRRLLGKRQRLLAYLAKKNRVRYKKLISQLDIREK
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACP_PSEPF
Sequence: MSTIEERVKKIVAEQLGVKEEEVVNTASFVEDLGADSLDTVELVMALEEEFETEIPDEEAEKITTVQAAIDYVTSHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRA32_HUMAN
Sequence: MDCCASRSCSVPTGPATTICSSDKSCRCGVCLPSTCPHTVWLLEPICCDNCPPPCHIPQPCVPTCFLLNSCQPTPGLETLNLTTFTQPCCEPCLPRGC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 3-2, High sulfur keratin-associated protein 3.2, Keratin-associated protein 3.2.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 3 family.
Protein: EX7L_RHIEC
Sequence: MSNLFDSDSPTNLAEYSVSELSGSIKRTIETAFDQVRVRGEISGYRGPHSSGHAYFALKDDRARIDAVIWKGTFSRLKFRPEEGMEVIATGKVTTFPGSSKYQIVIETLEPAGAGALMALIEERKRRLGAEGLFDAARKKRLPFMPHVIGVVTSPTGAVIRDILHRISDRFPVHVLVWPVKVQGEGSGEEVANAIRGFNALEPASAISRPDVLIVARGGGSLEDLWSFNDEIVVRAAAESRIPLISAVGHETDWTLIDYAADVRAPTPTGAAEMAVPVKAELEAQAAALAARLQGCMNRQMDQRRQSVRSLMRAFPSLDQLLALPRRRFDEAAAGLGRGLELNTINKRRGFERVIAHLRPDLLSGRISERRQMLNERMVRAERMVERLIDRSASRVERAEAILASLPARLKAQTDRSRERLGNLTRHADTAIRHQLTRARAELSAQDRVLQSLSYKNVLRRGYAVIRDEDNRPVSQAAALSAGMGIAIEFADGRIGAMTTEGGTPPGGAKKRSTKPAEPTKQGSLF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECM_ECOUT
Sequence: MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTLPVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQGIRAGPQRLS
What is the function of this protein?
Regulates secA expression by translational coupling of the secM secA operon.  Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
What are the official names of this protein?
Secretion monitor.
What is the protein family that this protein belongs to?
Belongs to the SecM family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Periplasm. Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease.
Protein: PYRD_HERAR
Sequence: MSEKFLYALARPFLFAIDPEAAHNLTLHALRRAASLGWTSAIAKPAHDPRTVMGITFPNPVGLAAGLDKDGAYIDGLATLGFGFIEVGTVTPHAQPGNPLPRMFRLPQANAIINRMGFNNGGVDAFVSNVQASRFYQNKEGILGLNIGKNADTPIERAVDDYLICLEKVYPYASYVTVNISSPNTKNLRQLQGASELDALLAQLKEAQQRLADQHQRYVPIALKIAPDIDTEQIQTIAQALLRHKMDGVIATNTTINREAVKNMKHAEEAGGLSGAPVFASSNAVIRALKAELGDALPIIGVGGILSGTDAQAKIAAGASLVQLYTGLIYRGPALIRECAAALRAPT
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CECD_GALME
Sequence: ENFFKEIERAGQRIRDAIISAAPAVETLAQAQKIIKGGD
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.  Has antibacterial activity against the Gram-positive bacteria M. luteus (MIC=34. 4 uM), L. monocytogenes (MIC=34. 4 uM), and S. lutea (MIC=34. 4 uM), and the Gram-negative bacterium E. coli D31 (MIC=8. 6 uM).  Lacks antibacterial activity against the Gram-positive bacterium B. circulans, and the Gram-negative bacteria E. coli ATCC 25922 and S. typhimurium.  Has antifungal activity against A. niger, but lacks antifungal activity against C. albicans, C. wickerhamii, F. oxysporum, P. pastoris, P. tannophilus, S. cerevisiae, T. harzianum, and Z. marxianus.
What are the official names of this protein?
Cecropin-D-like peptide.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1751_AERPE
Sequence: MEGTRSRVRITVEAEVRPTEDREKVLKAVRNVVEPESVRFEKIGSTEILVGESSTLASLSRLHSILRAERILDAARGAMKKGVQGADRMTIHLHKQAAYKGRLSFVSSDHESPMGAIRITIEHPNVREVIDWLAPPTVRGRPVFERRMPE
What are the official names of this protein?
UPF0201 protein APE_1751.
What is the protein family that this protein belongs to?
Belongs to the UPF0201 family.
Protein: RL19_META1
Sequence: MRTKLLELVEKDQIRTDLPEIREGYNVKVHVRIKEGNKERIQVFEGLVIASYGTGINKSITVRKDSYGVGVERIFKLNSPLIAHIEVTRINKVRRAKLYYMRDLKGKSARLKEIKKAK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: B2KB9_SICCD
Sequence: WIMGHMVNAIEQVDKFLNLGANAIEFDIDFDKDGIAQITHHGIPCDCGRKCTKKAIFTEYLDNIRQVTTPDDPKFREQLVLLALDLKLQRISSAKAYRAGEDVAKKLPDHYWQRGNSRARAYILLNIPLVEDYEFIRAFKDTLKNEGYESYNDKVGINFTGNEDLDKIRDVLEILGIHKQVWQADGITSCFARGTERLKEALEKRDTPGYNYINKVYAWTLVRKSIMRRSLRLGVDGVMSNNPDRVIKVLKEKEFADKFRLATYNDNPWEKFRG
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin SdSicTox-betaIIB1bix, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NU5M_PONAB
Sequence: MAMFTTMTALTLTSLIPPITATLINPNKKNSYPHYVKTAIASAFTISLIPTTMFICLGQETIVTNWCWTTTQTLQLSLSFKLDYFSMTFLPVALLITWSIMEFSLWYMASDPNINQFLKFLLIFLITMIILVTANNLLQLFIGWEGVGIMSFLLISWWYARTDANTAAIQAILYNRIGDIGFILALAWFLLHSNSWELQQVFLLNNNPNLLPLLGLLLAAAGKSAQLGLHPWLPSAMEGPTPVSALLHSSTMVVAGVFLLIRFHPLTENSPHIQTLTLCLGAITTLFAAICALTQNDIKKIVAFSTSSQLGLMMVTIGINQPHLALLHICTHAFFKALLFMCSGSIIHNLNNEQDIRKMGGLLKTMPLTSTSLTISSLALAGMPFLSGFYSKDLIIETANMSYTNTWALSITLIATSLTGAYSTRMILHTLTSKPHFPTPISINENNPTLLKPIKRLMLGSLFAGFLITNNIPPMSLPQVTTPPYLKLAALAATLLGLLVALDLNYLANKLKTKTPPPTFYFSIMLGFYPSIIHRMIPHLSLLMSQNLSLLLLDLTWLKKLMPKTISQHQTSASITISTQKGLIKLYFLSFLIPLLLILLMIS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RLMH_FRATH
Sequence: MMAFLLDIITFLQISFSTNIFRINYKWVSDGYDEYKKRLSKLIPLELIELPIAKRTKTGNPKLWMEQEAKTILGKLNDSDHLVILDVNSKIISTEELADKMQNWKFNNPNVVILIGGPDGIDQSIKDIAKEKISISKMTFPHPLVRIIAEQLYRAYTILEGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_BORPA
Sequence: MPHVDLNPLKQRMQAARAAAVAQFRQHPRPDMLLTELRRIVDQALRELVKLCPLPAGATLAAVGGYGRGELYPHSDVDLLILLPQPPSAADARAVEALVAALWDLGLEPGHSVRTLEDCEREARGDITVETALLESRWLAGSRTLMKRLDSAMQARLDAAVFFQAKRVEMQQRHARYQDTPYALEPNCKESPGGLRDLQVILWMARAAGFGHSWREVAQAGLLTSSEARDLRRAEQAFKRLRIELHLLTGRREDRVLFDLQPGLAAVYGIASTATRRASELLMQRYYWAARLVTQLNVILVQNIEERLFPRPDSDARLIDDDFRNLRERLDIVREDGFERNPTLLLRAFLVMQQHPELIGMSARTLRAIWHSRHRIDAQFRRNPVNRKLFLQILQQPRGIVHELRRMTMLNILPRYLPVFRRIVGQMQHDLFHVYTVDQHTLAVVRNLRRFTMPEHAQEYPLASQLIAGLDRHWLLYVAALFHDIAKGRGGDHSELGAREVRRFAQDHGLDPADAELVEFLVRHHLLMSAVAQKRDLSDPQVVRDFAAQVGDERRLAALYLLTVADIRGTSPRVWNAWKGKLLEDLFRLALAALGGAHADAHTVLTERKDEAARLTRLAGLRDDAREAFWNQLDIAYFLRHDASEIAWHTRHLYYQVAPDEPVVRVRPTEHGEGLQVMVYTRDAPDLFVTTCGYFDAKSLSVQDARVHTTRHGWALDSFIVLAPEGFADLRAQATLVEHELAERLRDPHAARHAHAPRRLPHSHARRSRVFPVMPQAELSPDERSQSWRLSVTATDRPGLLYALARVFAEHGVDLIMAKIMTLGERVEDVFIVSGSALERPRSQMQFERAILDALAGDEPRQQAA
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: NADD_LARHH
Sequence: MTVLPRVAIGLFGGSFDPVHEGHLRLARALRDELQLAEVRLLPAGTPPHRAPLAAAAADRLAMLRLALAGEPGLTVDERELSGRLSGYTVDTLAMIRRETGPEAALWWLVGGDQLASLDRWHRWRDLFGLAHLAVAVRPGFDAGSLPPAVAAEWQARQATDFANLPPAGRIRALSLSPVDISATAIRADLARGGDGLGHLAPAVRDYIHLHRLYRSESPA
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: FABZ_ECO57
Sequence: MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity).
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB2B_HUMAN
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:23001566, PubMed:28013290, PubMed:26732629).  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.  Plays a critical role in proper axon guidance in both central and peripheral axon tracts (PubMed:23001566).  Implicated in neuronal migration (PubMed:19465910).
What are the official names of this protein?
Tubulin beta-2B chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.