PharMolix/UniProtQA huggingface dataset:
Protein: NU6C_CUCSA
Sequence: MDLPGPIHDFLVVLLGSGLILGSMGVLLFNNSIYSAFSLGLVLVSISLFYILANAQFVAAAQLLIYVGAINVLIIFAVMFMKGSEYSKDFNLWTVGNGVTFLVCTSIFVSLMTTIVDTSWYGIIWTTRSNQILEQDLISNSQQIGIYLSTYFFLPFELISIILLAALIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y1136_STRA5
Sequence: MSEEKFDAKVDKVSGSVKESVGKLTGDKEVESEGKVDKLKGHAKEKLADIKDTIKGASESFKKKD
What are the official names of this protein?
UPF0337 protein SAG1136.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: RETR2_HUMAN
Sequence: MASGGGGGNTGAGGGPGMGLSLGLGLGLSLGMSEATSEAEEEAATAEAVGRLATTLWLRLRGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLWQPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKRQNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLLMQLDYSMKAEANALHHKHDKRKRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAVAEP
What is the function of this protein?
Endoplasmic reticulum (ER)-anchored autophagy regulator which exists in an inactive state under basal conditions but is activated following cellular stress (PubMed:34338405).  When activated, induces ER fragmentation and mediates ER delivery into lysosomes through sequestration into autophagosomes via interaction with ATG8 family proteins (PubMed:34338405).  Required for collagen quality control in a LIR motif-independent manner (By similarity).
What are the official names of this protein?
Reticulophagy regulator 2.
What is the protein family that this protein belongs to?
Belongs to the RETREG family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EXP22_ORYSJ
Sequence: MAPARPFALLFLAVTVGFVLLTAADDSANATATTTTAMAPSSSTDDAAPPVWLKAHATFYGGADASGTMGGACGYGDLYSQGYGTRNAALSTALFNDGASCGQCYKIACDRKRAPQWCRPGVTVTITATNFCPPNWDLPSDNGGWCNPPRPHFDMAQPAWEKIGIYRAGIIPVIYQRVPCVKKGGVRFTINGHDYFNLVLVTNVATTGLIKSMDVMGSNSTDWLPMVRNWGANWHSLSYLTGQMLSFRVTNMDGQTLVFRNIVPSGWKFGQTFASKLQFK
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-A22, Alpha-expansin-22, OsEXP22, OsEXPA22, OsaEXPa1.9.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: COBT_BRUA2
Sequence: MSASGLPFDDFRELIRNLPGPDLGAERAVREREVTLTKPAGSLGRLEEIVAWLATWTGKRTPQVNRPLVAVFAGNHGVTAKNITPFPPSVTAQMVENFAAGGAAINQICIANDLGLKVFDLALEHPTGDITEEAAMDEHTCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAIALALFGGTAEDWVGPGTGSTGELMQRKLAAVRQAVALHQPHLQDPLEVLRCLGGREIAAMAGAILAARMEKIPVIVDGFVASAAAAVLYAANPEAIDHCMFGHVSAEPGHRKLLAKMGKEPLLDLGMRLGEGTGAALAANIVKAAALCHSGMATFEQAGVSASK
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: CH60_SHIDS
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y066_HALSA
Sequence: MSGLTADLDAVAAAGGYDDTDAMVEEAVRELLRRRPELRLSLAVEKYQSGAVSLNRAAELAGVSVEAFKDELADRGIDRDAGFLTDAQRDDHLQTFME
What are the official names of this protein?
UPF0175 protein VNG_0066H.
What is the protein family that this protein belongs to?
Belongs to the UPF0175 family.
Protein: MTH1_HAEPA
Sequence: MDQRLICSNAIKALKNLEENSIDLIITDPPYNLGKDYGTTDDNLNFNKYLEFSHEWLEECYRVLKPHGTIYIFMGMKYISYIYKILEQDLGMYFNSWITWYYTQGIGKTRGYSPRHDDILMFTKHPKKFTFNLDRIRVPQKYYRSVNNMRGANPSNVWEFSHVHYCNKNRKPHPTQKPEALYERMILASSNEGDIVLDPFVGSGTLNFVCKHLNRSGIGIDINKEYIEMAKERLDSEFNGFDSIDERMKRCPNDLSDPVIRKQYIINHINWFLKNHENAREEFLNEVKTKYYKKMTQEEKRLLDKENNLSFDFS
What is the function of this protein?
A beta subtype methylase that recognizes the double-stranded sequence 5'-GTTAAC-3', methylates A-5 on both strands, and protects the DNA from cleavage by the HpaI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.HpaI, M.HpaI, Adenine-specific methyltransferase HpaI, Modification methylase HpaI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: ATPE_MARMM
Sequence: MADKLHFDLVSPERRLFAGNVDQVVVPGEEGDFGVLPNHAPFMSVIRPGAITVIDDGKETRTFIHGGFAEVTAAGLTILAEEAIAVADIDTEKLARDLSDAREDVTAAKDEEERDQAAALVAKYEAMQAVAAH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PHNC1_PSEU2
Sequence: MTLRLSAIELRHSDGTLALRGLDLSIARGERVAIIGPSGAGKTTLLNLLASALPPSAGQLQVLGTDPWQLSSKRRQRLRSRIALIHQAPPLPARQRVVTAVSAGRLGQWGLGKSLLNLLHPLDISGAREVLARLDLADKLFERCQQLSGGQLQRVGIARALYQQPELLLADEPVSAMDPRLADHTLALLGQHAIEHNVTLVASLHAVELALAHFPRIIGVRDGRIHFDLAASEVGREHLDTLYANEQLSPQPVSDAAETRWTPRC
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PURA_KLEP7
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKGLEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFADKLKEVMEYHNFQLVNFYKAEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINSLSGFCLTKLDVLDGLKEVKICVGYRMPDGREVTTTPLAADNWEGIEPIYETMPGWSETTFGVKERSGLPQAALNYIQRIEELTGVPVDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIM3_RAT
Sequence: MAKREDSPGPEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSAVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICGAKQKVLQTQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSAAAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELCAEITGPDGMRLAVPVVDHKNGTYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIVDELVFRVGSRGREKGEFTNLHPLSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
What is the function of this protein?
E3 ubiquitin ligase that plays essential roles in neuronal functions such as regulation of neuronal plasticity, learning, and memory (PubMed:20352094).  In addition to its neuronal functions, participates in other biological processes such as innate immunity or cell cycle regulation.  Component of the cytoskeleton-associated recycling or transport complex in neurons, polyubiquitinates gamma-actin, thus regulating neuronal plasticity, learning, and memory (By similarity).  Ubiquitinates postsynaptic scaffold GKAP, a neuronal substrate involved in synaptic remodeling and thereby modulates dendritic spine morphology (PubMed:20352094).  Positively regulates motility of microtubule-dependent motor protein KIF21B (By similarity).  Induces growth arrest via its RING-dependent E3 ligase activity and ubiquinates CDKN1A.  Positively regulates TLR3-mediated signaling by mediating 'Lys-63'-linked polyubiquitination of TLR3.  In turn, promotes the recognition and sorting of polyubiquitinated TLR3 by the ESCRT complexes (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 3, Brain-expressed RING finger protein, RING finger protein 22.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome. Golgi apparatus, trans-Golgi network. Cell projection, dendrite.
Protein: Y410_RHIME
Sequence: MIENKKKPNPIDIHVGSRIRLRRTMLGMSQEKLGESLGITFQQIQKYEKGTNRVGASRLQNISQILNVPVSFFFEDAPGDGGGTGPGMAEASSSNYVVDFLSSSEGLQLNRAFVKISDPKVRRKLVDLVKALAAEAESE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator R00410.
Protein: ARGC_THEP3
Sequence: MVKVGIFGATGYTGVELIRILSKHEKVEIKYLSSQSYNTKAISDVYSSLIGFCDKVLEEVDFQKAMSECDVIFTALPSGHASKIAREAVKKGVKVIDLGADFRFDDYSVYKEWYSGDYEDYGDIKRVYGIPEIYRDDIKEAQVVGNPGCYPTSVILGLMPLLKNGIIEGNIIVDSKSGVSGAGHNPSYNNMYAECNENIKAYNVAKHRHIPEMEQELSKIFGEKVSVVFTPHLAPMTRGILSTMYCKLKKDMDVNTVYNIYTDFYKNEYFVKVLKPGNYPATKNVYGSNFCHIGFEVDKHTNTLIVMSAIDNLVKGASGQAVQNMNIMFGIEENTALDIVPIYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_FRAAA
Sequence: MPSIEAVGAREILDSRGNPTVEVEVVLEDGTLGRAAVPSGASTGAFEAVELRDGEDRYGGKGVRKAVAAVIERIGPAIIELEATEQRLLDQTLIDLDGTPGKSALGANALLGVSLAVAKAAAAASGLPLFRYLGGPSAHLLPVPMLNILNGGAHADTNVDIQEFMIAPIGASSFSESLRWGAEVYHALKSVLKARGLGTGVGDEGGFAPSLPTNRDALDLIAEAVDKVGLRLGSDVALALDVASTEFYADGSYTFEGSTRTAEELSDYYAELVGAYPIVSIEDPLAEDDWSGWVALTERLGTKVQLVGDDLFVTNPERLARGIASKAANALLVKVNQIGTLTETLDAVNLAHRNGYRAMMSHRSGETEDTTIADLAVAVDCGQIKTGAPARSERVAKYNQLLRIEEELDDAARFAGAAAFPRHGQPA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MURC_ACTP7
Sequence: MKNFQDKIKKLVPEMRRVNQIHFIGIGGAGMSGIAEVLLNEGYQISGSDIAEGPVTKRLAEAGAKVFIGHQAENVAGASVVVASSAIDDSNPEVRAAKEARIPVIQRAQMLAEIMRFRHGIAVAGTHGKTTTTAMISMIYTEAKLDPTFVNGGLVKSAGKNAHLGASRYLIAEADESDASFLHLQPMVSVVTNIEPDHMDTYGGDFEQMKATYVKFLRNLPFYGLAVMCADDETVMEIAPQVGRQVLTYGFSEKADYRIEDYQQTGFQGHYTVVCPNGERIDVLLNVPGKHNALNATAALAVAKEEGIANEAILAALADFQGAGRRFDQLGSFIRPNGKVMLVDDYGHHPTEVDVTIKAARSGWENKRVVMIFQPHRYSRTRDLFDDFVQVLSQVDALIMLEVYAAGEAPIVGADSKALCRSIRNLGKVDPILVSDTDQLGEVLDQIIQDGDLILAQGAGSVSRISRGLAESWKA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_SHIBS
Sequence: MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_ECO24
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMDFADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLVGEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: CMOA_SHEB5
Sequence: MNVSQDTIYAQASEHISDFQFDNRVAGVFSDMIRRSVPGYTQIINTIGDFADRFVMPNTQIYDLGCSLGAATLSIRRQIQGRQCRIIAVDNSESMVARCQENLNAYVSDTDVDLVCGDIRDIDIQNASLVVLNFTLQFLPPEDRETLIAKIYQGLNPGGILVLSEKIRFEDAPIQTLLEEQHLDFKRANGYSELEISQKRSALENVMKPDTLTTHQQRLTSQGFSHFSLWFQCFNFASMVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: CAN1C_EMENI
Sequence: MSSDAMSDYSHDDEHDPQTDELRETALVTLEALISSCSSQMQSYLPNTINSALRFLKYDPNVADMGEDEEMSGTQDDGSEDDVTEEPDLEDDDFEDFEEEGGYSDIDDMSWKVRRCAAKLLYAVISTYGRGRALDDTSLYQQIAPAIVARFNKEREESVKLELVSTMDALVRKTAEGSMIMTSSGFLESVGSGSKISRKRRRQDSDASMIDFEPSMGTSSAAGTPLAAPSSPQSGPQSELANALPVIVRSLVTMWKQASIHLKQAIIILLKSLALVRYGGLADHLQQIEDPIADVLKSSLSGAPSASIGISASAGTLQIETLSLISAISETHASDALLPFLIALIPGVIVAVNDKNYKVSSEALAAVEQIVKALTPPRVTTASQDLIFQLEKLYDVSHSRITDTSADLEVRQRAIHVLGVLLARTSDEQGSAFLSFEKRSKGLVTLVDRLKNETTRLSAVRAIDDVAVLCSRKDDVDSNWVREVTAELGAQLRKSDRVLRSASLETLRSLSMNPNTRAHYDGETMKNLEECLIPLISVEDVHLLAPSLIIIAKLVPGNAQLLVNDGLVSAICSIVRTSLAGTVLKALLLLVKVIGEEGSGLTLMQNLLQDVGVNGDTSVVGRSIGTLLVHGGSNVGVRMEDFLSELQKTQDPQRQCLALAILGESALRLGASCSLTPNVFIPHFNSKSEKVRLASATALGNAAAGNVKAYLPTILGGLEKSDPQSYLLLHSVKELLQHPEMVRRDVAPSALKLWQALLVVSKEEDNRAMGAECVGRLALLDPPAYIPQFQEYLANGDAGIRSIVVSAFRFTLSDSRDVFNDVLRPLIVPLLVNMLSDRDLGNHRLALTTLNSAIHNKLALILPHLGELLPAVLGDTQIKPELIREVQMGPFKHKVDDGLELRKSAYETVYAALDTSFSLSHITELYSRILAGIDDEQDIRTICNLMTSKLITLAPEETQRHLDALSERYTAILNFKPKENAVKQEIEKAQEASTGVLKITRELSKAFPNAETMGDHHKWKAYMEMVRAQFGTQLSNLESEF
What is the function of this protein?
Assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes.  Acts as a F-box protein exchange factor when interacting with candA-N (By similarity).
What are the official names of this protein?
Cullin-associated NEDD8-dissociated protein 1, C-terminal part, Cullin-associated and neddylation-dissociated protein 1, C-terminal part.
What is the protein family that this protein belongs to?
Belongs to the CAND family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYCM_XENLA
Sequence: MNTLMRRACRRALFPGSFRLPALDPLNGTLMFSSGNACAAPVGCWAPPSGQDTGIKVYNSLTRKKEPLILADPTVATWYSCGPTVYDHAHLGHACSYVRFDTIRRILLKVFGIDIVMAMVVTDIDDKIIKRAKELNISPVALARTYEQDFKQDMTALRVLPPTVYMRVTESIPQIISFIQQIIANGHAYSTSQGNVYFDVQSIGDQYGKFNDSFCDAASESALQDKRHIRDFALWKTSKPEEPYWASPWGKGRPGWHIECSTIASSVFGKHLDIHTGGIDLAFPHHENEIAQCEAYHQSTQWGNYFLHTGHLHLKGNEEKMSKSLKNYVTIKEFLKSFSPDHLRMFCLRSKYKSAVEYSKESMHDAVNTLHLISSFVDDAKAYLKGQLICQPVQETLLWQRLNETKVNVKAAFSDDFDTPRAVDAVLDLIHHGNRQLKAVSKESSSPRSPIVYGAMVSYIEQFLEIMGISLGQNQVPAEERHSAMLFNVVEEMVSFRSKVRNYSLATNESATAIGQEEKQQYKERRRQLLLEREPLLQACDIARQHLAVYGINVKDRGDTSTWELLDRKEET
What are the official names of this protein?
Probable cysteine--tRNA ligase, mitochondrial, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DYN1_CAEEL
Sequence: MSWQNQGMQALIPVINRVQDAFSQLGTSVSFELPQIAVVGGQSAGKSSVLENFVGKDFLPRGSGIVTRRPLILQLIQDRNEYAEFLHKKGHRFVDFDAVRKEIEDETDRVTGQNKGISPHPINLRVFSPNVLNLTLIDLPGLTKVPVGDQPADIEQQIRDMILTFINRETCLILAVTPANSDLATSDALKLAKEVDPQGLRTIGVLTKLDLMDEGTDAREILENKLFTLRRGYVGVVNRGQKDIVGRKDIRAALDAERKFFISHPSYRHMADRLGTSYLQHTLNQQLTNHIRDTLPTLRDSLQKKMFAMEKDVAEYKNYQPNDPGRKTKALLQMVTQFNADIERSIEGSSAKLVSTNELSGGARINRLFHERFPFEIVKMEIDEKEMRKEIQYAIRNIHGIRVGLFTPDMAFEAIAKKQITRLKEPSLKCVDLVVNELANVIRQCADTMARYPRLRDELERIVVSHMREREQIAKQQIGLIVDYELAYMNTNHEDFIGFSNAEAKASQGQSAKKNLGNQVIRKGWLSLSNVSFVRGSKDNWFVLMSDSLSWYKDDEEKEKKYMLPLDGVKLKDIEGGFMSRNHKFALFYPDGKNIYKDYKQLELGCTNLDEIDAWKASFLRAGVYPEKQKAQEDESQQEMEDTSIDPQLERQVETIRNLVDSYMRIITKTIKDLVPKAVMHLIVNQTGEFMKDELLAHLYQCGDTDALMEESQIEAQKREEMLRMYHACKEALRIISEVNMSTLGDQPPPLPMSDYRPHPSGPSPVPRPAPAPPGGRQAPMPPRGGPGAPPPPGMRPPPGAPGGGGGMYPPLIPTRPGPGGPPPNMAPPR
What is the function of this protein?
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.  Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).  Required for coelomocyte endocytosis (PubMed:20803083).  Involved in apoptotic cell phagocytosis (PubMed:21490059).  Required for recruitment of phosphatidylinositol 3-kinase piki-1 to phagosomes (PubMed:22272187).  May play a role in rab-5 recruitment to cell-corpses-containing phagosomes but not to endosomes (PubMed:18425118).  Required for embryonic and larval development (PubMed:9294229, PubMed:21490059, PubMed:20803083).
What are the official names of this protein?
Dynamin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle, phagosome membrane; Peripheral membrane protein. Note=Microtubule- associated (By similarity). Transiently associates with cell corpses containing early phagosomes where it colocalizes with vps-34 and rab-5 (PubMed:18425118).
Protein: WCAM_SHIFL
Sequence: MPFKTLSRRTFLTASSALAFLHTPFARALPARQSVNINDYNPHDWIASFKQAFSEGQTVVVPAGFVCDNINTGIFIPPGKTLHILGSLRGNGRGRFVLQDGSQVTGGEGGGMHNITLDVRGSDCTIKGLAMSGFGPVMQIYIGGKNKRVMRNLTIDNLTVSHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISDHVIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNINARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVSLTNIEMKRASLELHNKPQHLFMRNINVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSSVDIDRINHHIVNVEKINFRLPERRE
What are the official names of this protein?
Colanic acid biosynthesis protein WcaM.
Protein: SIDT1_MOUSE
Sequence: MLDCLRLALLCALPWLLRAAVPGHQEEPLAKSAELRRDPRDPARGADFDRVYSGVVSLSTENIYSFNHTSHPGQVTAVRVHVNSSSDNLDYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSKATNETGPLEQLIFVDVASMAPHGAHYKLLVTKIKHFQLPTNVAFYFTASPSQPQYFLYKFPEDVDSVIIKVVSEKAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPDEQFFVVFVIKPEDYACGGSFSIQENENQTWNLQRSKNLKVTIVPSIKESVYVKSSLFSIFVFLSFYLGCLLVVLVHHVRFQRKSIDGSFGSSDGSGNMAVSHPITASTPEGSNYGAIDESSSSPGRQMSSSDGGQPCHSDTDSSVEESDFDTMPDIESDKNVIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDLLHRRALEAKDIFAMEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVITLTVLGVVFGKNDVWFWIIFSAIHILSSLALSTQIYYMGRFKIDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPLPVFCIAATAVVWAAALYFFFQNLSSWEGTPAESREKNRECVLLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF
What is the function of this protein?
In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp (PubMed:26067272).  Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded (PubMed:27046251).
What are the official names of this protein?
SID1 transmembrane family member 1.
What is the protein family that this protein belongs to?
Belongs to the SID1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.