PharMolix/UniProtQA huggingface dataset:
Protein: PHS_BRUAB
Sequence: MARNRLTESEMNEALRALDGWQKVDGREAITRSFKFKDFSTAFGFMAQAALYAEKLDHHPEWFNAYNRVDVTLATHSENGVTELDIKMARKMNAIAG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: Y2292_MYCTU
Sequence: MNPGFDAVDQETAAAQAVADAHGVPFLGIRGMSDGPGDPLHLPGFPVQFFVYKQIAANNAARVTEAFLQNWAGV
What are the official names of this protein?
Uncharacterized protein Rv2292c.
Protein: YEGS_SALAR
Sequence: MANFPDSLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVETVIAGGGDGTINEVSTALIQIRDGVVPALGLLPLGTANDFATSAGIPEALDKALKLAIAGNAMEIDMARVNDKTSFINMATGGFGTRITTETPEKLKAALGGVSYLIHGLMRMDTLKPDRCEIRGENFHWQGNALVIGIGNGRQAGGGQQLCPTALINDGLLQLRIFTGEELLPALFSTLTQSDDNQNIIDGASAWFDIHAPHEITFNLDGEPLSGQEFHIEVLPGALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_BURMA
Sequence: MNPEHSPLGKATVYANQYDASLLFPIPRAGAREQIGIGAPLPFFGTDIWNAYELSWLNARGKPQIAIATFYVPAESPNIVESKSFKLYLGSFAQTAFESADAVRDALKRDVSAACGASVTVRLATPAEFRKLQMDELDGLSLDRLDLDAHVYETDPSFLTASHDEAPVEETLVTDLLKSNCPVTGQPDWGSVQIHYVGAPIDHAGLLRYIISFRNHTGFHEQCVERIFVDILRACQPVKLAVYARYTRRGGLDINPFRTNYNQPMPDNARTARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_PSESM
Sequence: MTQTLADMRRDYTRDGLTEAQSPQEPFALFHTWFEEAVKTEQPPVEANAMTLATVDEEGRPHCRVLLLKGLDAQGFTFFTNYESAKGRQLAAHPFAAMTFFWPALERQVRIEGRVEKVSAQESDAYYQVRPLGSRLGAWASPQSRVIADRDELEGLIRQTEQRFADTQPHCPEHWGGYRLLPERIEFWQGRSSRLHDRLNYRLINAKWARERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: IBPA_YERPE
Sequence: MRNSDLAPLYRSAIGFDRLFNLLESGQNQSNGGYPPYNVELVDENNYRIAIAVAGFAEQELEITTQDNLLIVRGSHANEPAQRTYLYQGIAERNFERKFQLAEHIKIKGANLVNGLLYIDLERLVPESLKPRRIEIK
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB2A_MOUSE
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-2A chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ARNE_PSEU2
Sequence: MLASACLLTCLGQIAQKYAVQGWRGAFPGVFAALRSLWLALACLGSGLLIWLLVLQRLDVGIAYPMLGVNFVLITLAGRYVFNEPVDVRHWLGIALILVGVFQLGRQA
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SFC9_SCHPO
Sequence: MGKDVALDFLPSSLYSCTCSCDGKLAFCDSEKVQILVPSTEANTPKFMKALAYLDDVEDELPNCQMLAPNELRLGDLTPSVISRYVVWSPTGLADNYDPLLTVLTNRHRVYFFSSSSRVLHQKWTCVAQMSTHLPSDPLELCRIHSVAWSPLVSLPSSSPWGVCLFALGAESGHVHLSIMSHSSTPFFKSFDLNCSWVVQLSFSSWNVVGDSATCLLSCSSRNGEIRILKIAISSHSDTFDTAMQELPFSLDYRPFSPLLAWSSPLANVEYLALVYPGHLFAFRYDKSLGKFCSFLNHNLLSLCSPSGVLFGHNDIDTIYVYILTHSGTLETFSLLDNSISMLDSPERHVLEKFLNNHLQNYGSVSDDSIKTLKIHGFCPSPYLSSAALHFSISYPASFTYVVTAAERSYFNFIPSLFSKSVFSHMITSSLNNLCVAPSAGCLLEISLMNDTLKEKTDIFTMLTNSLSSFLVTDYDFFLELKHLIDISSLSNLYLDSSLNAMRLLYGWSVYKQKALDATLLNSLRYRLTLYIMLYTLSQISLDPSYLTSDCKAVLRNFVSFTYKELAEVPIAMEVANEIAKSLEVSSDFSETCPACEATVQFNNTSLATCDNGHVWRRCSVTMLLLSQKAAKYCAVCNSIVAIFNPSQTKCLLADLQNELSICFYCGGHFLVS
What are the official names of this protein?
Putative transcription factor tau subunit sfc9, TFIIIC subunit sfc9, Transcription factor C subunit 9.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBL_CABCA
Sequence: SVGFKAGVKDYRLTYYTPEYETLATDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTSEEMMKRAACARELGVPIVMHDYLTGGFTANTSLSHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ENGB_SALTY
Sequence: MTNLNYQQTHFVMSAPDIRHLPSDCGIEVAFAGRSNAGKSSALNTLTNQKSLARTSKTPGRTQLINLFEVVDGKRLVDLPGYGYAEVPEEMKRKWQRALGEYLEKRQSLQGLVVLMDIRHPLKDLDQQMIQWAVESNIQVLVLLTKADKLASGARKAQLNMVREAVLAFNGDVQVEAFSSLKKQGVDKLRQKLDSWFSELAPVEEIQDGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: Y1582_STAA3
Sequence: MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKVIGKAKEVVENAKNKITDAIDKLKK
What are the official names of this protein?
UPF0337 protein SAUSA300_1582.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: CLPS_KLEP3
Sequence: MSKRDWLDFEHLVDDEVRDAIKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLTVHYEGKAICGVFTAEVAETKVAMVNQYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: ATPD_SHELP
Sequence: MAELSTIARPYAKAAFDFAIEKNAVESWAEMLSFAAQVSENETMKPLLSGALSSSQLADLFIKVCGEQINEQGQNLIKVMAENGRLEVLPAVYELFHEFSNEWAKEVEASVVSATELSAEQQQQISASLEKRLTRKVKLNCSVDASLVAGVIITAGDLVIDGSVSGKLNRLSEKLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CH10_MYCTA
Sequence: MAKVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGPGRWDEDGEKRIPLDVAEGDTVIYSKYGGTEIKYNGEEYLILSARDVLAVVSK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_ROSS1
Sequence: MPQLGMGELLIILIIVLLLFGASRITGVASALGGSIKAFRKAVRDDDVPASKSEPAESTDKKVETNV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYD_BACLD
Sequence: MFGRTYYCGEITEKAIGETVVLKGWVQKRRDLGGLIFIDLRDRTGIVQVVFNPDVSKDALETAESIRSEYVLDITGKVVAREEATVNPNLKTGRIEIQAESVDVLSAAKTPPFAISDQAAEVSEDIRLKHRYLDLRRPEMFNSLKMRHNVTKAVRRFLDDNGFLDIETPVLTKSTPEGARDYLVPSRVHEGEFYALPQSPQIFKQLLMVSGFDRYYQIARCFRDEDLRADRQPEFTQIDIEMSFMSQEDIMKLSEEMMAHVMRETHGIEISLPLPRMSYEDAMNRYGSDKPDTRFGMLLTDVSEAVKDSDFKVFASAVANGGAVKAINVKGAAANYSRKDIDALGEFAANYGAKGLAWLKTEADGLKGPIAKFFAGEKQEALVQALDAADGDLLLFVADKLEVANDALGALRLKLGKELNLIDESLFNFLWVVDWPLLEYDAEEGRYYAAHHPFTMPVREDLKLIETNPQDMKAQAYDLVLNGYELGGGSIRIFEKDVQEKMFGLLGFSEEEAKEQFGFLLEAFDYGAPPHGGIALGLDRLVMLLSGRTNLRDTIAFPKTASASCLMTEAPSEVDNAQLDELHLEIKRKIRQ
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_PARD8
Sequence: MSEQKVVICKDLKSELQDFLSSLKYDKLFILMDTNTKEKCFPLVEDIPAFQKAPILVMEAGDMNKGFVSLAQIWTALSNEGASRNSLLVNLGGGMITDMGGFAGATFKRGIRTINIPTTLMASVDAAVGGKTGINFNGLKNEVGSFYPPLCVFIDCDFLRTLDRDNILSGYAEMIKHGLISSMENYASVMLFDIDTMNYSYLNSLVGQSVAVKERIVEEDPKEQGIRKALNFGHTIGHAFESLSFLKMRPILHGHAVAAGIVSELYLSHKLCGFPMEKLSQVVYYIKEYYPALFFDCTDYDTLYELMTHDKKNEGGIINFTLLKNVGDVRINQSVTKEKILESLDFYRESFGI
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPLA_STAA2
Sequence: MNKNVMVKGLTALTILTSLGFAENISNQPHSIAKAEKNVKEITDATKAPYNSVVAFAGGTGVVVGKNTIVTNKHIAKSNDIFKNRVAAHYSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFAEGAKAKDRISVIGYPKGAQTKYKMFESTGTINHISGTFIEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
What are the official names of this protein?
Serine protease SplA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: URED_STAAR
Sequence: MDEQQWTGQLDLTVFFDGNRSVSRDIFFEKALKVIRPVYLNQSTIPTFYIVNVGGGYLDGDRYRMNVNVEDNAKVTLTSQGATKIYKTPSNHVEQYQTFNLKDNAYLEYVADPIIAYENAKFYQHNTFNLNNSSSLFYTDILTPGYSKTGEAFKYQYMHLINEIYIEDELVTYDNLLLNPNKQSINEIGYMEHYSHYGSAYFIHEDVNQKLIDSVYETISSYSNTFDCRVAISQLPTHGFAVRIFAYRTQIIEKILGTIQSYIAENIYDRKLDFLRKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAP2_SALG2
Sequence: MDAATIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGIGGIPFDNYPFAYIVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFHLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQKHETGLDWMFAVHIIQQFGLGIVFGLGGGYLLQQMINRISLPSGLYPMLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVTPSDLWPIAVPALILSIWMIFFARPLSVFTGLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKRAKVVVPPVGWPVSRVGLDIHPDNPWEQFIYQLSADKWCVGAALRDLHMPNETRIAALFRNNELFHPTGSTRLQEGDVLCVIGRERDLPALGKLFSQSPPVSLDQRFFGDFILEANAKFADVALIYGLEEGTEYRDKQQTLGEIIQQLLGAAPVVGDQVEFGGMIWTVAEKEDNVVRKIGVRVAEDEAE
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYE_ACTP2
Sequence: MNIETLFPLDPNVKVRTRFAPSPTGYLHVGGARTALSSWLYAKHFNGEFVLRIEDTDLERSTPEATAAILEGMEWLNLAWEHGPYYQTKRFDRYNQVIDQMIEQGLAYRCYCSKERLENLRHEQEANKEKPRYDRHCLAHHDQPTDAPHVVRFKNPQEGSVVFDDAVRGRIEISNSELDDLIIRRTDGSPTYNFCVVVDDWDMGITHVVRGEDHINNTPRQINILKALGAPIPTYAHVSMINGDDGQKLSKRHGAVSVMQYRDDGYLPEALINYLVRLGWGHGDQEIFSREEMIELFDIHSVSKSASAFNTDKLQWLNQHYMRSLPAEHVAKYLAWHMNDQAIDTSSGPALEEIIPVLSERAKTLKELAAASRYFYQEFDGYDEKAAAKNFKAEAVAPLAKLLEKLTALTDWSVEAIHDAMNATAADLEIGMGKVGMPFRLAVTGSGQSPSMDITAKLVGRERTLARIQKAIEFIQAQA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y278_LISMH
Sequence: MWGYIHLISWVAIVVLTVTALLIYSKSVKSFTMLQMINRVFYILVILSGIMMVKYSIEQSWILAIFKILMGIIVIGVVEMLLSYRKQQKPTGMFLMIFVIVVVITISLGFYLSGGYPLFN
What are the official names of this protein?
UPF0344 protein LMHCC_0278.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPE_DESRM
Sequence: MGIRLKAHGKINLTLDVLDRRPDGYHEVEMIMQSISLHDVLEIEEQSKEISLTVSGISVTAEEDNLVLKAARLLQQVAGTGAGAKIHLQKNIPVAAGLAGGSTDAAATLKGLNALWGLGLSQEQLRQLATQLGADVPFCLAGGTAIARGIGEKLTTLEPAPPFGIILVKPSFGVSTAEVYQGLRLEHLGKRPNTEAMVKALKERDLGQVARELANVLESVTLRMHPKLEQIKEILRQIGCTGVLMSGSGPTVFGLTENREKAAELISGLPQAGCHVLAAWMV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: GPDA_SHEPA
Sequence: MKNTADITVLGAGSYGTALAISLASNGHRTMLWGHEPEHIENLKNDKSNEAFLPGIPLPDLLIPEADLATALAASNNVLVVVPSHVFGLVLTQAKPLLRKDSRIVWATKGLEPETGRLIQDVAREAIGDEFPLAVLSGPTFAKELAAGMPTAISIAGTDPQFTKDLVELLHSPKRLRVYANDDFIGLQLGGAVKNVIAIGAGLSDGIGFGANARTALITRGLVELTRLGEAMGAQASTFMGMAGLGDLVLTCTDNQSRNRRFGLALGKGSDVETAQDEIGQVVEGYRNTKEVYTLAKRLGVEMPITEQVYQVLYKGKSPVDAAKELLSREKKSETSSAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTAA_CERSK
Sequence: MAVKKRSIFEEVGQGAKAPVPQGGSIDRGHGGARRGIRLWLMALFLLVMAMIVVGGLTRLTESGLSITEWRPVTGAVPPLNETQWAAEFDKYRDSPQYRLMNAGMTLAEFQRIYWWEWGHRQLGRVIGLVWAVGFLGFLAARRIPRGWWPRLLALGALGGLQGGIGWWMVASGLEGDKVTVESTRLATHLGLAFIILGLIAWQALLLGRSESDLLQARRQKEGRLVTLTTVLIGVAFLQIVLGALVAGIDAGRGFPTWPDMNGTFLPADMFYVPGVETDWRNPAWWLGLLQNPGFVQFLHRMAGYALAALGLIFWIFGRRSRHRATRGAFDLLAMALLAQILLGVGTVLSAAEWQVAIAHQVGAVVIWVLILHARHLALYPRVGSIRKGTL
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TILS_MYCPA
Sequence: MDRPGALDRLRTAVEAFSTAHLGAVERWCVALSGGPDSLALTAVAARLRPTTAVIVDHGLQPDSAAVAQTARAQAIALGCVAAQVISVHVDGEGGLEAAARRARYAALAAHRDGPVLLGHTLDDQAETVLLGLGRGSGVRSIAGMRPHDPPWCRPLLGQRRAVTHAACAELGLTAWQDPHNSDRRFARARLRAEVLPLLEEVLGGGVVEALARTATALREDNELLDALAERALPAARAGAGLQVAALAGLDAPVRRRVIRAWLLAGGATGLTDKQIRGVDNLVTAWRGQGAVAVGSSLPGERLFAGRRDGVLTLWREPVR
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_THEAB
Sequence: MAKCQICGKGPASGKNVSHSNRRTNRWFRPNLQKVRVLREDGTVKRMWVCTDCLSAGKIKRYVSKSVEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TSAE_SYNY3
Sequence: MNENSMEFFLPDLNATDQWGQQLAQQLPLGTIILLQGDLGAGKTSLVQGLGRGLGITGEIVSPTFTIVNEYREGKMPLYHLDLYRLNTLEVEYLYPEQYWQGEDFPLGITAVEWPERLPQLPSQYLQIQLCHQGEGRSIALTAQDWAMDLKELLPPS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB.  TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE.
What is the protein family that this protein belongs to?
Belongs to the TsaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LC7L2_MOUSE
Sequence: MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVSKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASRDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI
What is the function of this protein?
May bind to RNA via its Arg/Ser-rich domain.
What are the official names of this protein?
Putative RNA-binding protein Luc7-like 2, CGI-74 homolog.
What is the protein family that this protein belongs to?
Belongs to the Luc7 family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm. Note=Colocalizes with SCNM1 and SNRNP70 in nuclear speckles.
Protein: GLPG_YERPA
Sequence: MTRVIVISNLRLAQAFVDYMATHHVALEIRPDAQGVEIWLADDEQLSAVQHELEQFLLDPLNPRYQAASWQAGNVNSNLPYQRFSYLQTLRSQAGPLTLSVMVLCIAIYILMLITGDMAVMSWLAWPYNSSQYLQIWRWVSHAFLHFSLLHILFNLMWWWYLGGQMEKRLGTSKLLVLTIVSAVFSGWGQSLFSGANFGGLSGVVYALMGYVWLTGERAPERGISLPRGLMAFSVLWLIAGYFDILGLSIANAAHVSGLIIGLLMAFWDTRNSARTVQ
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TXC01_LYCSI
Sequence: MKFAVILLFSLVVLAVASESVEEVRREIDIEDLPEQQRGCADLRQPCTEGDDCSCCGSEGVCNCSHPHKKGCYCKTAGPLEKLAKKFKGCKNK
What are the official names of this protein?
U12-lycotoxin-Ls1a, Toxin-like structure LSTX-K1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 31 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR9_HISS2
Sequence: MQLNHPIRQALLSVSDKSGIVEFAQGLVRRGVKLLSTGGTAKLLAENGIPVTEVSDYTGFPEMMEGRVKTLHPKIHGGILGRRGIDDEVMMQHQIDAIDMVVVNLYPFAATVAKPDCTLEDAVENIDIGGPTMVRSAAKNHQHVAIVVNNSDFNAILAEMDQNRNSLTLETRFDLAIKAFEHTAQYDSMIANYFGQMVKPYFRAEEEAEAKCGQFPRTLNLNFIRKQSMRYGENGHQKAAFYVEQDVKEASVSTAKQLQGKALSYNNIADTDAALECVKSFSEPACVIVKHANPCGVALGKDILEAYNRAYQTDPTSAFGGIIAFNRELDEDTAKAIIERQFVEVIIAPTVSSAAQEIVKSKKNVRLLMCGNWESAIQRLDFKRVNGGLLVQEADLSMVDLADLEVVSKRQPTKQELEDLLFCWKVAKFVKSNAIVYAKNNQTVGIGAGQMSRVYSAKIAGIKAKDEGLEVKGCVMASDAFFPFRDGIDAAAKVGIECVIHPGGSMRDQEVIDAANEHNMVMVLTKMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.