PharMolix/UniProtQA huggingface dataset:
Protein: TERL_BPP7
Sequence: MARSCVTDPRWRELVALYRYDWIAAADVLFGKTPTWQQDEIIESTQQDGSWTSVTSGHGTGKSDMTSIIAILFIMFFPGARVILVANKRQQVLDGIFKYIKSNWATAVSRFPWLSKYFILTETSFFEVTGKGVWTILIKSCRPGNEEALAGEHADHLLYIIDEASGVSDKAFSVITGALTGKDNRILLLSQPTRPSGYFYDSHHRLAIRPGNPDGLFTAIILNSEESPLVDAKFIRAKLAEYGGRDNPMYMIKVRGEFPKSQDGFLLGRDEVERATRRKVKIAKGWGWVACVDVAGGTGRDKSVINIMMVSGQRNKRRVINYRMLEYTDVTETQLAAKIFAECNPERFPNITIAIDGDGLGKSTADLMYERYGITVQRIRWGKKMHSREDKSLYFDMRAFANIQAAEAVKSGRMRLDKGAATIEEASKIPVGINSAGQWKVMSKEDMKKKLNLHSPDHWDTYCFAMLANYVPQDEVLSVEDEAQVDEALAWLNE
What is the function of this protein?
Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging.  Heterooligomerize with small terminase protein to be docked on capsid portal protein.  Forms a ring-like structure through which genomic DNA is translocated into the capsid.  May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation.
What are the official names of this protein?
Probable terminase, large subunit, DNA-packaging protein B, PACase B protein, Terminase B protein.
What is the protein family that this protein belongs to?
Belongs to the punalikevirus large terminase family.
Protein: SYW_THESM
Sequence: MPEFEVTPWEVTGVVDYNKLIEEFGTTPLTDDLLKKTEELTKKELPMYFKRKFFFSHRDYDLVLKDYEAGKGFFLYTGRGPSGPMHIGHIIPFFATKWLQENFGVNLYVQITDDEKFLFKPQLTFEGTKRWAYENILDIIAVGFDPDKTFIFQDSEFTKIYEMAIPIAKKVTYSMAKAVFGFNEQSKIGMIFFPAIQAAPTFFEEKRSLIPAAIDQDPYWRIQRDFAESLGYYKTAALHSKFVPGLMGLGGKMSASKPETAIYLTDDPEEAGKKIWKYALTGGRATAKEQRELGGEPDKCVVFKWLEIFFEPDEKKLLERYIACKNGEILCGQCKRYLIEKVQNFLKEHQEKREKAKKEIEKFKYTGDLAREQWDKAIPEPLRK
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIP3_MOMCH
Sequence: MVKCLLLSFLIIAIFIGVPTAKGDVNFDLSTATAKTYTKFIEDFRATLPFSHKVYDIPLLYSTISDSRRFILLNLTSYAYETISVAIDVTNVYVVAYRTRDVSYFFKESPPEAYNILFKGTRKITLPYTGNYENLQTAAHKIRENIDLGLPALSSAITTLFYYNAQSAPSALLVLIQTTAEAARFKYIERHVAKYVATNFKPNLAIISLENQWSALSKQIFLAQNQGGKFRNPVDLIKPTGERFQVTNVDSDVVKGNIKLLLNSRASTADENFITTMTLLGESVVN
What is the function of this protein?
Irreversibly relaxes supercoiled DNA and catalyzes double-stranded breakage.  Acts also as a ribosome inactivating protein.
What are the official names of this protein?
Ribosome-inactivating protein beta-momorcharin, B-MMC, MAP 30, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: LPXH_MANSM
Sequence: MKKTYFISDLHLSENRPKLTALFEHFMHNIAPQAQAVYILGDLFDFWVGDDEKSPLISRVQAQIKQLTEKNIPCYFIHGNRDFLLGEKFAESCGLQLLPDYKIVNLYGTDTLICHGDTLCTDDVNYQTFRRKVHQKWRQRLFLLLPLKVRIKIADKIRRQSRHDKKMKSAEIMDVNGEFVCQIFERFNVRQMIHGHTHRQNIHQIPPHFKRIVLGDWHDDYASILEVSEQETYFLPQTAR
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DIRC2_RAT
Sequence: MGSGWSSEEEERQPLLGPGLGPAPGATRRGREAAAVLPAAGPSPGRVYGRRWLVLLLFSLLAFAQGLVWNTWGPIQNSARQAYSFTGWDIALLVLWGPIGFLPCFAFMWLLDKRGLRITVLLTSFLMVLGTGLRCIPVSDLTLKKRLIHGGQILNGLAGPTVMNAAPFLSTTWFSADERATATAIASMLSYLGGACAFLVGPLVVPAPNGTAPLLTAESSRDHIKDRIETVLYAEFGVVCLIFSATLAYFPPRPPLPPSVAAASQRLSYRRSFCRLLSNLRFLMIALAYAIPLGVFAGWSGVLDLILTPVHVSQVDAGWIGFWSIVGGCVVGIAMARFADFIRGMLKLILLLLFSGATLSSTWFTLTCLNSVTHLPLTTVTLYASCILLGVFLNSSVPIFFELFVETVYPVPEGITCGVVTFLSNMFMGVLLFFVTFYHTELSWFNWCLPGSCLLSLLLILCFRESYDRLYLDVVVSV
What is the function of this protein?
Electrogenic metabolite transporter.
What are the official names of this protein?
Solute carrier family 49 member 4, Disrupted in renal carcinoma protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: ASPG1_DROER
Sequence: MKRHLGTCLWVLCLASTAFSSLAVTTSPKPTLASAFSGKSKTTAGTTAVKANKTTVELLPMVINTWKFTAANVLAWRILKQSKGGLRQTRNAVVEGCSKCEKLQCDRTVGYGGSPDELGETTLDAMVMDGATMDVGAVAGLRRIKDAIKVARHVLEHTQHTMLVGDAASAFANAMGFESESLITPESKDMWLQWTAENCQPNFWKNVHPDPKVSCGPYKPRPTPLTRWKEDRARNEYEIGRKNHDTIGMIAIDVESNIHAGTSTNGARHKIPGRVGDSPIPGAGAYADNEVGAAVATGDGDVMMRFLPSLLAVEAMRAGKPPAEAAQEGLRRILKYHKDFMGALIAVDRLGNYAAACYGLDEFPFMVSSPAGTDGPTRLETVKCIAGQDKVNVVSL
What is the function of this protein?
Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.
What are the official names of this protein?
Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase GG24090, Aspartylglucosaminidase, AGA, Glycosylasparaginase, N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
Protein: YCEI_SALDC
Sequence: MKKNLLGFTLASLLFTTGSAVAAEYKIDKEGQHAFVNFRIQHLGYSWLYGTFKDFDGTFTFDEKNPSADKVNVTINTNSVDTNHAERDKHLRSAEFLNVAKFPQATFTSTSVKKEGDELDITGNLTLNGVTKPVTLEAKLMGQGDDPWGGKRAGFEAEGKIKLKDFNITTDLGPASQEVELIISVEGVQQK
What are the official names of this protein?
Protein YceI.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ASNA_SHIB3
Sequence: MKTAYIAKQRQISFVKSHFSRQLEECLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T22D3_MOUSE
Sequence: MNTEMYQTPMEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVALDNKIEQAMDLVKNHLMYAVREEVEVLKEQIRELLEKNSQLERENTLLKTLASPEQLEKFQSRLSPEEPAPEAPETPETPEAPGGSAV
What is the function of this protein?
Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.
What are the official names of this protein?
TSC22 domain family protein 3, Glucocorticoid-induced leucine zipper protein, TSC22-related-inducible leucine zipper 3, Tilz3.
What is the protein family that this protein belongs to?
Belongs to the TSC-22/Dip/Bun family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. Nucleus. Note=Localization depends on differentiation status of myoblasts. In undifferentiated myoblasts, isoform 1 localizes to the cytoplasm, but in differentiating myoblasts, isoform 1 is localized to the nucleus. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm. Nucleus. Note=Localization depends on differentiation status of myoblasts. In undifferentiated myoblasts, isoform 4 localizes to the cytoplasm, but in differentiating myoblasts, isoform 4 is localized to the nucleus.
Protein: INS_CANLF
Sequence: MALWMRLLPLLALLALWAPAPTRAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEDLQVRDVELAGAPGEGGLQPLALEGALQKRGIVEQCCTSICSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_BUCAT
Sequence: MSKITKIIAREIIDSRGNPTVESEVHLEGGFVGLASSPSGASTGSLEALELRDENKDRFMGKGVEKAVSLINEKISIALKNKNARNQSDIDHIMIDLDGTINKSKLGANAILSVSLAVAKAAAASKRMPLYAHIAEINETPGVFSMPLPMINIINGGKHANNNIDIQEFMIQPISAKTVKESIRIGCEIFHALGELLKEKGMSTTVGDEGGYAPNLKSNEEALNIIQDAIQKTKYKLGQDIRLAIDCAASELYNKNEKKYNLKGENISFSSKEFTHYLEKLSQKYPIVSIEDGQDESDWEGFLYQTHVLGHKIQLVGDDLFVTNKNILKKGIKKGIANSILIKLNQIGTLTETLEAIKTAKQANYGVIISHRSGETEDASIADLSVGTSSGQIKTGSMSRSDRTSKYNQLIRIEENLGTKYAPFHGLREIKSAF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y512_METJA
Sequence: MIFMVLGKIKSLLPNSQILTKVKIVDIRRKESEEGSIFYIGTMVDKDGVANFITTIPLERGKCYEIFGRITEEKSVRIVEKVIKGVKYPREIPEIPKEQLYNRGEVLDVKVPAILEVSQSTIFVNYYCKICRGIVDTKIKPRGLVYICRNCGEIDPEDVDVKIKVFGKIHFGTSSKRCYIPPATLEQFMPGILDMLEEYGIDDTIREICLKLNGKTFLVRGFEGKEGNYIITEMEDI
What are the official names of this protein?
Uncharacterized protein MJ0512.
Protein: NDF6B_DANRE
Sequence: MLTVPFEEPDMMRESQFGATFTRQEDVRTLSSAELKEAEDDNTDREEEEEREEDENGLPKKKGPRKKKSEGRGDRVKMRRQEANARERSRMHGLNDALESLRKVVPCYSKTQKLSKIETLRLAKNYIWALSETLSAGKRPDLLAFVQTLCKGLSQPTTNLVAGCLQLNARNFLTDHNGDVSFSGRPAYDSLYPYPNAEMATPTGLSSGTRESVKPFRPYNYYASYESYYDSASPESSSPHFDGQMSPPINYNGIFSLKKHDEQVEYSKNCHYGMRYCNVPGRGSMYRVSPDSHFPYDLHPRSQSFQSQDELNTGYHN
What is the function of this protein?
Differentiation factor required for neurogenesis (By similarity).  Does not act as an upstream activator of isl1.
What are the official names of this protein?
Neurogenic differentiation factor 6-B, NeuroD6-B, Protein atonal homolog 2-B.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTHY_YEAST
Sequence: MMGRGKLILIEGLDRTGKTTQCNILYKKLQPNCKLLKFPERSTRIGGLINEYLTDDSFQLSDQAIHLLFSANRWEIVDKIKKDLLEGKNIVMDRYVYSGVAYSAAKGTNGMDLDWCLQPDVGLLKPDLTLFLSTQDVDNNAEKSGFGDERYETVKFQEKVKQTFMKLLDKEIRKGDESITIVDVTNKGIQEVEALIWQIVEPVLSTHIDHDKFSFF
What is the function of this protein?
Catalyzes the conversion of dTMP to dTDP.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: GSPC_AERSA
Sequence: MTLPFRDDLLSSLLARCKTVPLSRFSQPLFWLLLLLLAHQCAGLTWRLLDLGSQQSSQPWQPAVAGSQGQGKARLDLGGVSRLALFGKAKQQARAADAVAADAPKTQLNAQLNGVLASSDPAKSIAIIAHSGVQNSYGIGDFIDGTQAKVRQVFADRVIIERDARDETLMLDGEEYGKPLPKQGNPDEKLSSVRSELLGNPGKITDYLNISPVRVDGRMVGYRLNPGSNPELFNQLGLVANDMAVSINGLDLRDNAQAMQAMQQVAGATEMTVTVERQGQLYDVYVGLSE
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
What are the official names of this protein?
Type II secretion system protein C, T2SS protein C, General secretion pathway protein C.
What is the protein family that this protein belongs to?
Belongs to the GSP C family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: RL1_CHLMU
Sequence: MTKHGKRIRGIQEKYDFTKPYSLGEAIDILKQCPAVRFDQTVDVSVKLGIDPRKSDQQIRGSVSLPHGTGKVLRILVFAAGDKAAEAIEAGADFVGSDDLVEKIKGGWVDFDVAVATPDMMREVGKLGKVLGPRNLMPTPKSGTVTTDVVKAIAELRKGKIEFKADRAGVCNVGVAKLSFDSAQIKENIEALCAALVKAKPATAKGQYLVNFTISSTMGPGVTVDTRELIAL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NUDT5_HUMAN
Sequence: MESQEPTESSQNGKQYIISEELISEGKWVKLEKTTYMDPTGKTRTWESVKRTTRKEQTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEFVEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHANAKPFEVPFLKF
What is the function of this protein?
Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate (PubMed:27257257).  In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10567213, PubMed:10722730, PubMed:19699693, PubMed:21389046, PubMed:17052728).  Can also hydrolyze other nucleotide sugars with low activity (PubMed:19699693, PubMed:21389046).  In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate.  Nuclear ATP synthesis takes place when dephosphorylated at Thr-45 (PubMed:27257257).  Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257).  Does not play a role in U8 snoRNA decapping activity (By similarity).  Binds U8 snoRNA (By similarity).
What are the official names of this protein?
ADP-sugar pyrophosphatase, 8-oxo-dGDP phosphatase, Nuclear ATP-synthesis protein NUDIX5, Nucleoside diphosphate-linked moiety X motif 5, Nudix motif 5, hNUDT5, YSA1H.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VDR_MOUSE
Sequence: MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIMKRKEEEALKDSLRPKLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPIRADVSTGSYSPRPTLSFSGDSSSNSDLYTPSLDMMEPASFSTMDLNEEGSDDPSVTLDLSPLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTLDDMSWDCGSQDYKYDITDVSRAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGNEIS
What is the function of this protein?
Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity).  Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity).  The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity).  Plays a central role in calcium homeostasis (PubMed:32354638).  Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites (PubMed:12016314, PubMed:32354638).
What are the official names of this protein?
Vitamin D3 receptor, VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes mainly to the nucleus. Translocated into the nucleus via both ligand-dependent and ligand- independent pathways; ligand-independent nuclear translocation is mediated by IPO4.
Protein: NAGAB_BOVIN
Sequence: MLLKTVLLLALASQVLVLENGLLRKPPMGWLAWERFRCNIDCSEDPKNCISEQLFMEMADRLAQDGWRDLGYVYLNIDDCWIGGRDAKGNLVPDRKRFPHGIAFLADYAHSLGLKLGIYEDLGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCYSTPQERAEGYPKMAAALNATGRPIAFSCSWPAYEGGLPPKVNYTLLADICNLWRNFDDIQDSWRSVLSVLDWFVTHQDVLQPIAGPGHWNDPDMLLIGNFGLSFEQAQAQMALWTVLAAPLFMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRILKEKSHIEVYLRPLASEASAIVFFSRRMDMPYHYHSSLARLNFSSSVVYEAQDVYTGDIISGLQDKTNFTVIINPSGVVMWYLYPIRKLEIPQQ
What is the function of this protein?
Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides.  Required for the breakdown of glycolipids.
What are the official names of this protein?
Alpha-N-acetylgalactosaminidase, Alpha-galactosidase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: GLPK_BDEBA
Sequence: MFMSSFIMAIDQGTTSSRTCIINQAGGLVAEAREAFKQIFPKPGWVEHDPEDIWYSTQRSMRLALEKAKIKGSQIRTIGITNQRETVMLWDAKSGKALHNAIVWQCRRTQDLCEKLKKNKKEKIITAKTGLVLDPYFSATKIQWLLKNVPNAAKKAKDGQALAGTVDSFLLWKLTAGHSHKTDVSNASRTMLMNIHTGWWDEDLLKIFGVPEAILPEICPSNSDFGVTQGLGFMPDGIPITGIVGDQQAALFGQTCFETGDSKCTFGTGSFLLLNTGKKAVKSKNKLLTTIAWKLKNQEMTYALEGGAFVCGAAVQWLRDGLGLIQQSSDVEALAKTVDGTDGVEFVPALTGLGAPHWQPEARGLICGLTRGSTKAHIARATLEAMALQNVDILNTMQRDLGKKLRGVRVDGGAAANDLLMQMQADYCGANVVRPQNLETTALGAAFMAGLGAGVWKDLKEIKRVWKVNKEFKVKMTPKARKERLQRWAQALERV
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: KYNU_NEMVE
Sequence: MAYKPTQTLRKLAEKSSLDIVSREFADYMDSKDPLRKMRDEFFYPRVKDLPGVDLSLVDGDQDSIYFCGNSLGLQPRGCRELIDRSLTKWEQMGVLGHTSGWCPWKPIEDILIKPMAEIIGAKDIEVVAMNTLTVNLHMMMVPFYRPTPQRYKILMEGKAFPSDQYAAQSQVHFHGFDPDKDIIEVFPREGEQSLRTEDILSAIEEHGNSITLVLFSGVQYYTGQFFDMKTITAAAQKKGCVVGWDLAHAVGNVELHLHDWNVDFACWCTYKYLNSGPGGIAGAFVHEKHAYNFELPKFAGWWGTDRNSRFQMRKEFEQIPGAHGYQCSNPPVFQCLLLRASLDVFEKTSVKEIRAKGDLLTAYLELLLLHYFSPSNDITKNGNTPHVSIITPADPKDRGCQLSVKFSVPVDKVFEELCKRGFVGDIRHPDVMRIAPAPLYNSFADVHRFISMLNAAFKTITPNS
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JOX4_ARATH
Sequence: MATCWPEPIVSVQSLSQTGVPTVPNRYVKPAHQRPVFNTTQSDAGIEIPVLDMNDVWGKPEGLRLVRSACEEWGFFQMVNHGVTHSLMERVRGAWREFFELPLEEKRKYANSPDTYEGYGSRLGVVKDAKLDWSDYFFLNYLPSSIRNPSKWPSQPPKIRELIEKYGEEVRKLCERLTETLSESLGLKPNKLMQALGGGDKVGASLRTNFYPKCPQPQLTLGLSSHSDPGGITILLPDEKVAGLQVRRGDGWVTIKSVPNALIVNIGDQLQILSNGIYKSVEHQVIVNSGMERVSLAFFYNPRSDIPVGPIEELVTANRPALYKPIRFDEYRSLIRQKGPCGKNQVDSLLLTR
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase involved in the oxidation of jasmonate (JA), a stress-induced phytohormone synthesized in response to attack by pathogens and herbivores, which triggers the activation of defense responses via the JA-mediated signaling pathway (PubMed:28760569, PubMed:28559313).  Converts JA to 12-hydroxyjasmonate (12OH-JA), an inactive form of JA (PubMed:28760569, PubMed:28559313).  Is specific to free JA, and cannot oxidize the bioactive form jasmonoyl-L-isoleucine (JA-Ile) or other JA-amino acid conjugates (PubMed:28760569).  Prevents over-accumulation of JA and indirectly its bioactive form JA-Ile under stress response (PubMed:28760569, PubMed:28559313).  Acts as negative regulator of JA-mediated defense signaling, by contributing to 12OH-JA accumulation, which represses JA defense responses upon infection by the fungal pathogen Botrytis cinerea (PubMed:28760569, PubMed:28559313).  Acts as negative regulator of JA-mediated defense responses upon infestation by the herbivorous caterpillar Mamestra brassicae (PubMed:28559313).
What are the official names of this protein?
Jasmonate-induced oxygenase 4, 2-oxoglutarate-dependent dioxygenase JOX4, Anthocyanidin synthase, Jasmonic acid oxidase 4.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: HCYA_CONCC
Sequence: LMRKDVDTLTD
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin subunit A, CCH-A.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: VNS3_AHSV4
Sequence: MNLAAIAKNYSMHNGESGAIVPYVPPPYNFASAPTFSQRTSQMESVSLGILNQAMSSTTGASGALKDEKAAFGAMAERLRDPEPIRQIKKQVGIRTLKNLKMELATMRRKKSALKITILISGCVTLATSMVGGLSIVDNEIFEDYKKNDWLMKAIHGLNLLCTTVLLAAGKISDKIQEEISRTKRDIAKRESYVSAASMSWNGDTEVLLQGIKYGDS
What is the function of this protein?
May play a role in the release of virions from infected cells.
What are the official names of this protein?
Non-structural protein NS3.
What is the protein family that this protein belongs to?
Belongs to the orbivirus NS3 family.
Protein: AQP7_MILTA
Sequence: MAHNEKDPSSVEPIKRKRFSNEYVRLFLAEFLGTFILIVFGCGTVAVTILSKHQSQDFFSVNVGFFLGIAFGVFIAGGVSGGHLNPAVTLAFAVINKCKWRKVPVYMAAQYLGAWVGSAILTAIYYDALHNHDQGNRTIETAGIYASYPQEFLTWQGGLADQIFATLLLMMGILALTDERNMVGPTGRAYVPLLVGLLVLAIGLAFGFNCGYPINPARDFGPRLFTAMAGWGTQVFSEPRGTYNWWWIPIIGPHVGAIIGALAYNFFIGYHWPKERDDVQLQSPSSPIVIVKNDAYQPLRPSRSVYSEELRITTS
What is the function of this protein?
Aquaglyceroporin that may modulate the water content and osmolytes during anhydrobiosis (PubMed:23761966).
What are the official names of this protein?
Aquaporin-7, AQP-7.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BQMT_SYNY3
Sequence: MPEYLLLPAGLISLSLAIAAGLYLLTARGYQSSDSVANAYDQWTEDGILEYYWGDHIHLGHYGDPPVAKDFIQSKIDFVHAMAQWGGLDTLPPGTTVLDVGCGIGGSSRILAKDYGFNVTGITISPQQVKRATELTPPDVTAKFAVDDAMALSFPDGSFDVVWSVEAGPHMPDKAVFAKELLRVVKPGGILVVADWNQRDDRQVPLNFWEKPVMRQLLDQWSHPAFASIEGFAENLEATGLVEGQVTTADWTVPTLPAWLDTIWQGIIRPQGWLQYGIRGFIKSVREVPTILLMRLAFGVGLCRFGMFKAVRKNATQA
What is the function of this protein?
Involved in a key methylation step in both tocopherol (vitamin E) and plastoquinone synthesis.  Catalyzes the conversion of 2-methyl-6-phytyl-1,4-hydroquinol (MPBQ) to 2,3-dimethyl-6-phytyl-1,4-hydroquinol (DMPQ, a substrate for tocopherol cyclase), and 2-methyl-6-solanyl-1,4-benzoquinol (MSBQ) to plastoquinol.
What are the official names of this protein?
2-methyl-6-phytyl-1,4-hydroquinone methyltransferase, 2-methyl-6-phytylbenzoquinone/2-methyl-6-solanyl-1,4-benzoquinone methyltransferase, MPBQ/MSBQ methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.