PharMolix/UniProtQA huggingface dataset:
Protein: MOAC_HELPG
Sequence: MLLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHGVKKGPVLQTAIIAGIMGAKKTSELIPMCHSIMLNGVDIDILEEKETCSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CLPP1_LEPIC
Sequence: MSVIPYVIEQTSRGERSYDIFSRLLKDRIIFLGNAINDDYANVITAQLLFLEAENPERDIYLYLNSPGGYVSSGLAIYDTMQYIKPDVRTLCLGQASSMAALLLAGGAAGKRSALPNARIMMHQPMGGATGQASDIEIQAREVLKLKEILNSIYHKHTGKTVEQIQKDTERNFYMTADEAKNYGIIDTVIQIDRKQTE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPHB_COMTE
Sequence: MTIVHRRLALAIGDPHGIGPEIALKALQQLSATERSLIKVYGPWSALEQAAQICQMESLLQDLIHEEAGSLAQPAQWGEITPQAGLSTVQSATAAIRACENGEVDAVIACPHHETAIHRAGIAFSGYPSLLANVLGMNEDEVFLMLVGAGLRIVHVTLHESVRSALERLSPQLVVDAVDAAVQTCTLLGVPKPQVAVFGINPHASEGQLFGLEDSQITAPAVETLRKCGLAVDGPMGADMVLAQRKHDLYVAMLHDQGHIPIKLLAPNGASALSIGGRVVLSSVGHGSAMDIAGRGVADSTALLRTIALLGAQPG
What is the function of this protein?
Involved in the degradation of terephthalate (TPA) via the protocatechuate (PCA) 4,5-cleavage pathway.  Catalyzes the dehydrogenation of 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate (DCD) to yield protocatechuate (PCA) (By similarity).
What are the official names of this protein?
1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase, DCD dehydrogenase, Terephthalate dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
Protein: Y304_HAEIN
Sequence: MMELQGKFLIAMPHLDDYFNRTVVFMCEHNEQGSMGLVINQPTDLSIAELYSKLNFMMKNDRTFGNEMVVAGGPMHTERGFILHKNTLNAFQHTYKVTKELSMTTSADVVETLGSTFAPEKYLVALGCSSWGAGQLEKEIRDNAWLVVSSNDQILFDMPYEDRYAAANQLLGIHPYNFALAQVGHS
What are the official names of this protein?
UPF0301 protein HI_0304.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: GLMU_THET8
Sequence: MHAHVILAAGQGTRMRSRLPKVLHPLLGKPMLLYALEAALALKPERLVVVVGHGGEKVVEALEGYPVEVAWQKEQLGTAHALLQAEGLLRDFPGPFLVTQGDTPLLSPRTLEALLRRVREGAGMALLTAELPDPTGYGRILREGEEVLGNVEEKDAPPEVRAIREVNAGAYAFDGFLFQALKEVRNENAAREYYLPDLIAIYRAHGRRVLAVRGVAEEALGVNTREELARVEGVLLRRLRAEWMGKGVRMILPETIYLEPSVELAPDVTLWPGAVLKGKTRIGEGCEVGPYAVLEDTVLEPGAKVLAHTVAQGAHLHPGASAGPFARLRPGAVLMEEVHVGNFVEVKNSLLHKGVKAGHLAYLGDAEVGEGTNIGAGVITANYDGKRKHKTEIGKKAFIGSNSVLVAPVRVGDRALVGAGSVITQDVPEGALAVARERQKNLEGYALRKLGEG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_XANAC
Sequence: MALNLSQKQEVVAELADIAAKAHSLIAAEYAGTTVSQMTAMRKQARETGVFLKVVKNTLAARAVEGTDFAVAADKLVGPLLYAFSMEEPGAAGRLIKEFAKSNDKLQAKVVSIGGELFPAGHVDVLASLPTRDQALAMLARVLSEPAAMFARAVKAVGDKQGGGDEAAAPVAETAEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CLPP_AQUAE
Sequence: MNHKEILDQLVPIVIEQTPRGERAYDIYSRLLQDRIVLLGSPIDDHVANLIVAQLLFLESQDPDKDIYLYINSPGGSVTAGLAIYDTMQYIKPDVVTICMGQAASMGAILLAAGAPGKRYALPHSRIMIHQPLGGIQGQATDIIIHAEEIKRIKEMLIDILAKHTGQPKDKIANDIERDYFMSPYEAKDYGLIDKVIEKRE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNAA_DICDI
Sequence: MGDDAKAKEFLDAADKRLRGGNFFKMFGGGSSRYDDAASDYTKAANLFKMSKKWDQAGAAFQKAAECFLKGSSKHDAASSYVLAAGCYKKGNVIDAITCLKAAIEYYTDEGRFAISAKHQKEIAELYEAEGDFDQAIASYQIASDYFDGENSTVSSHQCLLKIALFSAQLERYEKSIEIYEQVAAASLDNNLTQWGCKEYFLRACLCYLAADDVVGAERALQRYKDMQASFNSTRECRLLDGIIQACRNNNVEDFTNEVAEFNSISPLDSWKTSILLRIKNTINRETESVV
What is the function of this protein?
May be required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity).  Involved in vesicle fusion with nsfA and probably SNARE proteins.
What are the official names of this protein?
Alpha-soluble NSF attachment protein, SNAP-alpha, N-ethylmaleimide-sensitive factor attachment protein alpha.
What is the protein family that this protein belongs to?
Belongs to the SNAP family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein.
Protein: PI3R6_MOUSE
Sequence: MESSDVELDFQRSVQAVLRELNTPNPALQSNQGMWRWSLHKKVERNPGKSSILVRILLRELEKAESEDGRRVIIPLLLTLMSVLTKATGIPEDLYHRAYTFCTRLLTLPAPYSTVALDCAIRLKTETAVPGTLYQRTVIAEQNLISELYPYQERVFLFVDPELVSASVCSALLLEIQAAQEQQTPEACMRHVVSHALQAALGEACHTGALNRKLQASSRRVLEYYFHAVVAAIEQVASEDSPSRLGHLEKMEEIYCSLLGPATTRRHCVGDLLQDRLPSIPLPSPYITFHLWTDQEQLWKELVLFLRPRSQLRLSADLDALDLQGFRLDRDLARVSTDSGIERDLPLGSDELPDPSSSEMERAALQRKGGIKKRVWPPDFFMPGSWDGPPGLHRRTGRPSGDGELLPGVSRVHTARVLVLGDDRMLGRLAQAYYRLRKRETKKFCLTPRLSLQLYYIPVLAPQVTGQDPEASRKPELGELASFLGRVDPWYESTVNTLCPAILKLAEMPPYLDTSRTVDPFILDVITYYVRMGTQPIYFQLYKVKIFTSLSHDPTEDIFLTELKVKIQDSKSPKEGSSPRRRGAAEGTGAELSMCYQKALLSHRPREVTVSLRATGLVLKAIPAGDTEVSGFFHCTSPNAASATDCSCLHVSVTEVVKSSNLAGRSFTTSTNTFRTSSIQVQSQDQRLLTLWLDKDGRRTFRDVVRFEVSPCPEPCSRTQKSKTSALNSHGQETEKNMAKPNSLLMPINTFSGIIQ
What is the function of this protein?
Regulatory subunit of the PI3K gamma complex.  Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers.  The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G proteins than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG.  Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS.
What are the official names of this protein?
Phosphoinositide 3-kinase regulatory subunit 6, Phosphoinositide 3-kinase gamma adapter protein of 87 kDa, p84 PI3K adapter protein, p84 PIKAP, p87 PI3K adapter protein, p87PIKAP.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Translocated to the plasma membrane in a Ras-dependent manner (PubMed:19906996).
Protein: C3H43_ORYSJ
Sequence: MPQDDDWFWGRPTPVVVGDGETTSKPKPPVAGKTKKVEEQHPRRPGEPDCSYYVKFGSCKFGISCVYNHPDPRPQHGADDKKPAEQFPRRPGEPDCSYYVKFGSCKFGMNCRFNHPPRMPVPPQQEYFSGNACHCHHIEGKSKVEQVKLNVLGLPLRPGTGLCSYYMNRGICKFGTNCKFDHPDPGSDHEKWVVSSNANQVSSQVNIYSVLDHGESNEHTFTSEEVHQPGIPSFHQRISYTRDQLLQLCQNVEVPKDILKFCQDINVELNGEDKISGFGAEKDHVQTPSYKRFDATDSRDWHSWSAQTNWEQKFWDNFSEAKEPYSLGWKQEKFNKPDQSSFHFDSKDQWLKFIKCTPCKSTLIKAEVPLSIQRGIISGKDEVLKTLKSILNTFSPKMFDLQKGQLIETRISSADILKDVINLIFEKVVAEPAFCSTYAQLCTYLNQNLTPFPPEDCDCEEITFKQALSNKCQEIFESAHTVCSEIGKLIGQDREMEQRDKERVVKLETLGNINFIRALLKKKLITNKIIDHIVQAVMDCCKFRFEPLGKVDLLNIIFEGMLDSDSAGDESNICVNAMIGGNKSSIASNDVEMTRKNVNRQNEEAILQKSYDEVPNNKMDPQKNYADGAISYLIEKEKPTNLESSVRICRGGCSISEIMELVVDAGAVEGSDEHFMATLLFIKPEYREIFLTLDTREGRLGWLKRMYKVKE
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 43, OsC3H43.
Protein: YNEJ_ECOLI
Sequence: MDLTQLEMFNAVAEAGSITQAAAKVHRVPSNLTTRLRQLETELGVDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAVRIPATLAEFNRRYPKIQFSLSTGPSGTMLDGVLEGKLNAAFIDGPINHTAIDGIPVYREELMIVTPQGYAPVTRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESYHGMLACVIAGAGIALIPRSMLESMPGHHQVEAWPLAEQWRWLTTWLVWRRGAKTRPLEAFIQLLDVPDSARQGYQ
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YneJ.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RS13_LISW6
Sequence: MARIAGVDVPREKRIVISLTYIYGIGKQTASEVLAEAGVSEDTRTRDLTEEELGKIREILDRIKVEGDLRREVNLNIKRLIEIGSYRGMRHRRGLPVRGQNTKNNARTRKGPSKTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RPOC_MYCS2
Sequence: MLDVNFFDELRIGLATADDIRNWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITSVDDEMRHNELSTLEAEMAVEKKAVEDQRDADLEARAQKLEADLAELEAEGAKSDVRRKVRDSGEREMRQLRDRAQRELDRLDEIWNTFTKLAPKQLIVDEVLYRELQDRYGEYFTGAMGAESIKKLIENFDIDAEAESLREVIRSGKGQKKLRALKRLKVVAAFQQSGNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGKPLAMPRLDMVTGLYYLTTLVEGATGEYQAATKDAPEQGVYSSPAEAIMAMDRGALSVRAKIKVRLTELRPPTDLEAQLFENGWKPGDAWTAETTLGRVMFNELLPKSYPFVNEQMHKKVQARIINDLAERFPMIVVAQTVDKLKDAGFYWATRSGVTVSMADVLVPPQKQEILERHEAEADAIERKYQRGALNHTERNESLVKIWQDATEEVGKALEEFYPADNPIITIVKSGATGNLTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERGPDGTLIRDAHVETSAFARTLATDAVDANGNVIIERGHDLGDPAIDALLAAGITTVKVRSVLTCTSATGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVTGGADIVGGLPRVQELFEARVPRNKAPIADVAGRVRLEESDKFFKITIVPDDGGEEVVYDKLSKRQRLRVITHEDGTEGVLSDGDHVEVGDQLMEGAADPHEVLRVQGPREVQIHLVKEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGSTEFLPGSLTERAEFEAENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGISRYRNIQVQPTEEARAAAYTIPSYEDQYYSPDFGQATGAAVPLDDYGYSDYR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: TRMB_BUCAI
Sequence: MKNNIITPRYNLEGVFLRQIHSFVCRKGRTTTSQLSAIKKYWSLIGVDFQLNALNFSSIFKHRAPIILEIGFGSGESLVKTAMNFPEKNFLGIEVYKSGIGSCLHYASSYQIQNLRIIYYDATEVMYNMIPDDTLSKVQIFFPDPWHKKRHHKRRLLKNIFLKIITKKLIIDGILHIATDSESYAFYILDEIKDIKNYKNLSEKNNFVKRPVSRIITKFEKKGLLQGKKIFDLMFQLKK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: 1105L_ASFB7
Sequence: MLVIFLGILGLLANQVSSQLVGQLHPTENPSENELEYWCTYMECCQFCWDCQNGLCVNKLGNTTILENEYVHPCIVSRWLNK
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-5L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
Protein: NAGB_ECOSE
Sequence: MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: FIBA_BISBO
Sequence: EDGSDPASGDFLAEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: RS7_STRR6
Sequence: MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVYGAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SYT_ACIC5
Sequence: MEKQIQVTLPDGTVKTFPAGTTPFQVAESISPRLAQAAVVARIQTTQPAAATVTAGSEADSKTASEAAMYSAADPGAPRLVDLSTPLEEDVQLALLTEKDPEALKVLRHSAAHLMATAVLELFPETKLGHGPATDAGFFYDFYRPTPFTPEDLKLIEGRMAEIAQRNDKFVREFIPREEGLAEFKAGDDFMKVHFIERFTQPGEAISLYRNGNFVDFCRGPHVPSTNRIKAFKVTNLAGAYWLGDEKNPQLQRLYGTAFFSKKDLDEHFARLEEIAKRDHRVLGKQLDLFSIQEIAGAGLIFWHPKGAMIRKIMEDWMREECIRRGYDLVYTPHVMRVQLWKTSGHEGFYSQNMFTPMELDDAEYRLKPMNCPGHILIYKSQPRSYRDLPVRYAELGNVYRYERSGTMHGLLRVRGFTQDDAHIFCTPEQIEDEVVACIDFAQSVLTTFGFMDFQVELSTWDPNDRKNYAGSDDKWNLAISSLESALTRKGIAYKTIAGEAAFYGPKIDIKLVDVLGRLWQLSTVQFDFNLPARFELEYVGEDGERHQPVMVHRALYGSVERFFGVLIEHYAGAFPLWLAPVQIGLVPISERHLAYAEKVQQQLEAAGFRVELDRRNEKMNAKIRDFTLQKFPYVLIMGDKEAEAGAVSVRTRGKGDQGSLPLDEFIGRATTLIDTKSGDL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SHEPW
Sequence: MSDRVIIFDTTLRDGEQALAASLTVKEKLQIALALERLGVDVMEVGFPVSSPGDFESVQTIARTVKNSRVCALSRALEKDIDAAAQALSVADQFRIHTFISTSTIHVESKLKRSFDQVLEMAVGAVKYARRFTDDVEFSCEDAGRTPIDNLCRMVEEAIKAGARTINIPDTVGYTVPSEFGGIIQTLFNRVPNIDQAVISVHCHDDLGLSVANSITAVQHGARQIECTVNGIGERAGNCSLEEIAMILSTRKGELGLETGINAKEIHRTSSLVSQLCNMPVQANKAIVGANAFTHSSGIHQDGMLKAQNTYEIMTPESIGLNRNNLNMTSRSGRHVIKHRMSELGYGDQDYDMDVLYEDFLVLADKKGQVFDYDLEALAFMEAQAEDDDHFKLQQLVVHSDSTEGSATATVKVEVNGETVTEAAIGNGPVDAAYKAVARASGCEIDITSYQLGAKGEGQNALGQVDITASYRNQNFHGVGLATDVVEASVKALVHVMNLTWRADKVADCKQKIQQEKQVLGGV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: SYM_THEPD
Sequence: MGDKARRKWLVLAAWPYAYGVPHLGNLIGSVLSADVAARFLRLAGDEVVFVSGSDMHGTPIEVEALKRGESPKDLAERNHEKIKELFERWEISFDNYSKTESPTHIKFVQDFYRRVYENGYVFSDTVQLYYCPKDKIFLPDRYIVGTCPYCGYDRAYGDQCENCGRLLEPTLLLNPRCAICGSTPELRTTTHWFFDLPKLTDALKRYIEENENLPPNARNMSLQILRDGLKPRALTRDNKWGIPAPFPGAEDKTIYVWMEAVLGYISATIEYFASKGEPEKWKEFWLDPETRSVYFIGKDNIPFHTLILPALLIASGEKYVLPWTVASTEYLLFRGLKFSKSRRIGVWIDEALEVFPADYWRFVLVSLRPEQKDMSFTWEEFLRIVNNDLNDNIGNFVHRVLVLVQRKFGGIAPAPLDFADEDLKFREEILARSREVAEFMYAFRFKEALTHILWLSSSGNSYLNFRKPWELDSESARTPAFLALHAVKALAIMLYPIIPRSSQEMWKLLGYKDDIANHRWHEINEAVPPGQELPSPRPLFRKISEEELKAAVEKIEELRASRSS
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_STRP8
Sequence: MSTSFENKATNRGVITFTISQDKIKLALDKAFNKIKKDLNAPGFRKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGKEWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEAAQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVTFPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKELEAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEMYFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYNMPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ULAR_SALSV
Sequence: MTEAQRHQILLDMLAQLGFVTVENVIERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTADGLYKTDMLTAMAEQKMLSVVGKLVALVDSSKIGERAGMLFSRADQIAMLITGKNANPQVLQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AF111_ALTAL
Sequence: MTYEKPDLKRTKATVSFKRIYLHRASEFPGPWLCQCSSIMAQYHAWRGDLPRYLHVLHEKYGDFVRYAPNHVSIRHCDVWEDVYGFQRNVSKYDTTYSPFRLAPDFTSTWNTSNVDVHKSRRKLLNKLFSEQHLDDYGTLITVQVDEFMRQILEALPKDKDVMAGPINFAYKSDVVAREIITSLVSGQTYGFQSGDAKSASLLADISKFERKLYLLGFAPWLKMLPSFKPTLALAQWIVQSSKQGLASGSKNTLVAKMLAARDEEKDVEFSRNDVIADARFFLLGGSVTSSSALSATLFFLLHHPVEMQELYDELRGIFPTYEDIKADAQLMRCKRLRAVFEESMRLAPPVPTLLPRLVGPGGIKACGRYVPEGVVIGAPCWAISRDKRYFDKPNVFKPDRWLADSSDPVALEKMLLATRASQPFSYGPRACPGRALAFRENGLLLAKLVYAFEMEPVQDKSIVEESLTGICDGLVFNQLDTVGAHEVELMVRYRLRLDGKTKRRVSGN
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AF-toxins responsible for Alternaria black spot of strawberry disease by the strawberry pathotype (Ref. 1).  AF-toxin I and III are valine derivatives of 2,3-dyhydroxy-isovaleric acid and 2-hydroxy-isovaleric acid respectively, while AF II is an isoleucine derivative of 2-hydroxy-valeric acid (PubMed:15066029, Ref. 1, PubMed:22846083).  These derivatives are bound to a 9,10-epoxy-8-hydroxy-9-methyl-decatrienoic acid (EDA) moiety (PubMed:15066029, Ref. 1, PubMed:22846083).  On cellular level, AF-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).  The aldo-keto reductase AFTS1 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV) by reduction of its ketone to an alcohol (PubMed:15066029).  The acyl-CoA ligase AFT1, the hydrolase AFT2 and the enoyl-CoA hydratases AFT3 and AFT6, but also the polyketide synthase AFT9, the acyl-CoA dehydrogenase AFT10, the cytochrome P450 monooxygenase AFT11 and the oxidoreductase AFT12 are all involved in the biosynthesis of the AK-, AF- and ACT-toxin common EDA structural moiety (PubMed:12019223, Ref. 1, PubMed:18986255).  The exact function of each enzyme, and of additional enzymes identified within the AF-toxin clusters have still to be determined (PubMed:12019223, Ref. 1, PubMed:18986255).
What are the official names of this protein?
Cytochrome P450 monooxygenase AFT11-1, AF-toxin biosynthesis protein 11-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: METK_FRAT1
Sequence: MSKNYLFTSESVSEGHPDKLADQISDAILDEILKQDKNARVACETLVKTGMALVAGEITTSAWVDIEELVRNVITETGYDNASKGIDGRTCSVINAIGKQSRDITQGVDRGSLEDLGAGDQGLMFGFATNETPTLMPSAIYYSHLLMRKQAELRKSGKLAWLRPDAKAQVTLAYENDKPKFIDTIVLSTQHNESISQKELHDAVIEEIVKKVIPNELITKDTKYHINPTGVFLIGGPQGDCGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSGAYMGRYIAKNIVAAGLADKCEVQVAYAIGVAKPVSLMVNTFGTGKITDNQIEKLVAEVFDLRVGKIIENLDLLRPIYRKTSNYGHFGRELPEFTWEKIDKADILKSAARI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWP28_SOLLC
Sequence: VKIGTYELLKGDFSV
What are the official names of this protein?
38 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: CYB6_PHAAO
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFSSVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLAVLTASFGVTGYSLPWDQIGYWAVKIVTGVPEAIPIIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFPMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.