PharMolix/UniProtQA huggingface dataset:
Protein: PEPE_ECOL6
Sequence: MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQTWDDYTAKTAAVLASLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGLLAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGEEAVPLEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAC_BACCN
Sequence: MEKVLVFGHKNPDTDAICSAIAYAELKKELGMNAEPVRLGEISGETQFALDYFKVEGPRFVETVANEVDNVILVDHNERQQSANDIESVRVLEVIDHHRIANFETSDPLYYRCEPVGCTATILNKMYKENGVAIRKEIAGLMLSAIISDSLLFKSPTCTEQDVAAARELAEIAGVDAESYGLEMLKAGADLSGKTMEQLISLDAKEFQMGNAKVEIAQVNAVDTNDVLVHQAELEKVISAVVEEKGLDLFLFVVTDILTNDSVGLAIGKAANAVEKAYNVTLENNTATLKGVVSRKKQIVPVLTETFQAL
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AUG1_ARATH
Sequence: MSDVTGDLAAVSEAKGGSDAARISEVKAWLTSQFEAVGKEVPNFEYTHRSITHLYNLATASQAKSQAATIVANDFRLKASEYRAQAARIREILESAGMSQESLPSNVVSSAQVLANVANLLNIRDTELSSFLVAMGDISLRKTGVEEKRAKAQKESNALLDYTRKAIQRLTYLKKILAQLEDDVVPCESQMENWKTNLEVMAVKEEQYIQQYKKYEQMLLNRVGYTPKISHRELVEMAEHRKELDKMTKPVLDTLRSYQDLPPDKALAALAIEDKKRQFTAAEKYLEEVLQSALETNDE
What is the function of this protein?
Involved in microtubules reorganization during spindle and phragmoplast development.
What are the official names of this protein?
AUGMIN subunit 1.
What is the protein family that this protein belongs to?
Belongs to the HAUS1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Note=Preferentially localizes to microtubules minus ends.
Protein: RS2_DEIGD
Sequence: MSYISMKQLLEAGVHFGHETKRWNPKFKRFIFAERNGIFIIDLQKTLKQIDRSFDYIKDLAERGGVILFVGTKKQAQEIVELEARRTGMPYVTSRWLGGMLTNFRTIRTRIDRLNELDDMFESGRVNDRPKAERIELAAERERLLRFVGGIRKMTRLPDAIFVVDPTKEVIAVQEANKLGIPVIALADTDSDPDVIDYIVPGNDDAIRSIQLITHRIGDLIVEARGGGEDVSGERVSPDNADIEAAEDGEEVDNAQLTSSQGRS
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: IHFA_CAUVN
Sequence: MKGATLTRADLCEAVHEEVGLTRQDCAGLVERTLDLVAEALEQGETVKLSGFGVFQVRAKRARMGRNPKTGEPAEIEPRRVIGFRASQVMKARIDRALGG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: SRDI_NEUCR
Sequence: MHLSSSLLFTSALLAGGINASPATNAYRRQGADMRTIIGDTTPVLSNTTAVHFPGSGDFFSVTERWDVYRPPSYQAAITPTTEADIVSLVKMAKQHNIPFLATGGRHGYGTSLGKCQEGLAIDLSHFKDVKIDKQRETVTIGPGVVFADVFPVVSDAGYQVQTGTCSCVGMIGATIGAGIGRLDGVHGLVIDALESVRMITANGDIVEASKTKNPELFWGIRGAGANFGIITQATYKMHKSMGDIISFDLIYEPEQNVTLFNTVANMYLPPGLTVETIMSYNQTTEKPTIIVSSTYAGGSEAEARRWMQPLLRLNPWYKDIKAIPWKRMSKETALGLDKEVCANSQVFDIYGVNLRRHDANTWVKTFNKLAKFWNEQPAAQSSSVVLETWPNQAVVAVPDSETAYPWRDATTYVMIQMRWDAPGNPVETVADAMGRELRNDFAKTSGYNGLTVYVNYAHGDETPEQMYGRNKLHRLAKLKKQYDPSSVFGFHNPLPTSYP
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of sordarial, a salicylic aldehyde structurally related to the phytotoxin pyriculol (PubMed:19277664, PubMed:28485098, PubMed:30908040).  The most interesting aspect of this pathway is formation of an aromatic product from the highly reducing polyketide synthase srdA (PubMed:30908040).  SrdA synthesizes a reduced polyketide chain from one molecule of acetyl-CoA and five molecules of malonyl-CoA (PubMed:30908040).  The polyketide chain is then reductively released as an aldehyde (PubMed:30908040).  The oxidoreductases srdC, srdD and srdE then oxidize one of the hydroxy groups to facilitate the intramolecular aldol condensation, followed by dehydration to yield a salicylic aldehyde (PubMed:30908040).  This aldehyde can undergo facile reduction by endogenous reductases to yield the alcohol 1-hydroxy-2-hydroxymethyl-3-pent-1,3-dienylbenzene (PubMed:30908040).  The flavin-dependent srdI counteract against the propensity of the aldehydes to be reduced under physiological conditions and is responsible for reoxidizing 1-hydroxy-2-hydroxymethyl-3-pent-1,3-dienylbenzene back to the salicylic aldehyde (PubMed:30908040).  This salicylic aldehyde is then selectively epoxidized by the cupin-domain-containing oxidoreductase srdB to yield the epoxide, which can be hydrolyzed stereoselectively by the hydrolase srdG to give the final product sordarial (PubMed:30908040).
What are the official names of this protein?
FAD-linked oxidoreductase srdI, Sordarial biosynthesis cluster protein srdI.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: CYSD_SALAR
Sequence: MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANTYGCELLVHKNPEGVAMDINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINTGESIRVFPLSNWTEQDIWQYIWLENIEIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: PURZ_BPS2L
Sequence: MLSIPPYYRVKNCNLIVDCQYGSTGKGLLAGYLGALEAPQVLCMAPSPNAGHTLVEEDGTARVHKMLPLGITSPSLERIYLGPGSVIDMDRLLEEYLALPRQVELWVHQNAAVVLQEHRDEEAAGGLAPGSTRSGAGSAFIAKIRRRPGTLLFGEAVRDHPLHGVVRVVDTRTAQDMLFRTRSIQAEGCQGYSLSVHHGAYPYCTARDVTTAQLIADCGLPYDVARIARVVGSMRTYPIRVANRPEAGEWSGPCYPDSVECQFADLGLEQEYTTVTKLPRRIFTFSAIQAHEAIAQNGVDEVFLNFAQYPPSLGALEDILDAIEARAEVTYVGFGPKVTDVYHTPTRAELEGLYARYRR
What is the function of this protein?
Involved in the synthesis of the atypical nucleotide dZTP (2-amino-2'-deoxyadenosine-5'-triphosphate) (PubMed:33926955).  Catalyzes the condensation of aspartate with deoxyguanylate into dSMP (N6-succino-2-amino-2'-deoxyadenylate), which undergoes defumarylation and phosphorylation respectively by host PurB and guanylate/nucleoside diphosphate kinases to give dZTP (PubMed:33926955).  dZTP is integrated into the viral genome instead of adenine by the viral DNA polymerase.  This Z-base probably completely replaces adenosine and forms a triple bond to the opposite T-base (PubMed:33926955).  The resulting non-standard viral DNA is called Z-genome (PubMed:33926955).  The chemically modified DNA is probably harder for the host bacteria to digest with nucleases or restriction enzymes (Probable).
What are the official names of this protein?
N6-succino-2-amino-2'-deoxyadenylate synthase, 2-amino-2'-deoxyadenylo-succinate synthase, PurZ.
What is the protein family that this protein belongs to?
Belongs to the Caudovirales PurZ family.
Protein: MENC_ENT38
Sequence: MRGAQVYRWQIPMDAGVVLRDRRLKTRDGLFVHLQQDDRQGWGEISPLPGFSLESLAEAEAALLAWVNAWRIGESPALPAIPSAAFGISCALAELDGTLPEAADYRAAPLCSGDPDELFESLAAMPGEKIAKVKVGLYEAVRDGMVVNLLLEAIPDLRLRLDANRAWTPLKAQQFAKYVNPDYRDRIAFLEEPCKSRDDSRAFAQETGIAIAWDESLREAGFEFVAEPGVTALVIKPTLTGSLDKVREQVAAAHALGLTAVISSSIESSLGLTQLARIAAWLTPQTIPGLDTLNLMQSQLVRRWPGNPLPYLDIEALEPLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: TATB_VIBVY
Sequence: MFDIGFWELVLIFVVGLVVLGPERLPHAIRSVARFVSAAKSMANSVKDELAHELKVQELQENLRKAEQMGMEELSPDLKASVEQLKQAAQSVNRPYADVSAKNEATSSSSSDATHQTEATKTSAANTKSE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SOR_THEKO
Sequence: MLSQTIKSGDWKGEKHVPVIEYEKEGDLVKVEVSVGKEIPHPNTPEHHIAWIQLWFHPEDGAFPILVGKVEFSNHTDPLTEPRAVFFFRTQKKGKLYALSYCNIHGLWENEVTLE
What is the function of this protein?
Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
What are the official names of this protein?
Superoxide reductase, SOR.
What is the protein family that this protein belongs to?
Belongs to the desulfoferrodoxin family.
Protein: ADAB_BACSU
Sequence: METNKPTLYWSLLMFKDWNFYIASTLKGLVFVGSQNKPIEELFEWARKRFPGSLLVEDDDKLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQLAVWNALCEIPYGQTKSYSDIANDINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEMKTLLLDLEKRASSEMDVPH
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, inducible, O-6-methylguanine-DNA alkyltransferase, O6-methylguanine-DNA methyltransferase, MGMT.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
Protein: S29A4_MOUSE
Sequence: MGSIGSQRLKEPCVAATSDQSVVTSFSFDNFQLETTAEGAQDPGIRVRGVPTFTDSAVEEPVPDDRYHAIYFAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALAAVLLNNVVVERLNLHTRITTGYLLALGPLLFISICDVWLQLFSHDQAYAINLAAVGTVAFGCTVQQSSFYGYTGLLPKRYTQGVMTGESTAGVMISLSRILTKLLLPDERASTIIFFLVSAGLELLCFLLHLLVRRSRFVLYYTTRPRDSRPVQAGYRVHHDVASGDIHFEHQTPALSSSRSPKESPAHEVTHSNSGVYMRFDVPRPRVKRSWPTFRALLLHRYVVARVIWADMLSIAVTYFITLCLFPGLESEIRHCVLGEWLPILVMAVFNLSDFVGKILAALPVEWRGTHLLACSCLRVVFIPLFILCVYPSGMPALRHPAWPCVFSLLMGISNGYFGSVPMILAAGKVSPKQRELAGNTMTVSYMSGLTLGSAVAYCTYSLTRDAHGSCFQTATAAAANDSIPVGP
What is the function of this protein?
Electrogenic voltage-dependent transporter that mediates the transport of a variety of endogenous bioactive amines, cationic xenobiotics and drugs (PubMed:16873718, PubMed:23255610).  Utilizes the physiologic inside-negative membrane potential as a driving force to facilitate cellular uptake of organic cations (By similarity).  Functions as a Na(+)- and Cl(-)-independent bidirectional transporter (By similarity).  Substrate transport is pH-dependent and enhanced under acidic condition, which is most likely the result of allosteric changes in the transporter structure (PubMed:16873718).  Implicated in monoamine neurotransmitters uptake such as serotonin, dopamine, adrenaline/epinephrine, noradrenaline/norepinephrine, histamine and tyramine, thereby supporting a role in homeostatic regulation of aminergic neurotransmission in the central nervous system (PubMed:23255610).  Also responsible for the uptake of bioactive amines and drugs through the blood-cerebrospinal fluid (CSF) barrier, from the CSF into choroid plexus epithelial cells, thereby playing a significant role in the clearance of cationic neurotoxins, xenobiotics and metabolic waste in the brain (PubMed:23255610).  Involved in bidirectional transport of the purine nucleoside adenosine and plays a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia (PubMed:16873718).  May be involved in organic cation uptake from the tubular lumen into renal tubular cells, thereby contributing to organic cation reabsorption in the kidney (PubMed:23255610).  Also transports adenine and guanidine (PubMed:16873718).
What are the official names of this protein?
Equilibrative nucleoside transporter 4, mENT4, Plasma membrane monoamine transporter, PMAT, Solute carrier family 29 member 4.
What is the protein family that this protein belongs to?
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Note=Located to the plasma membranes of ventricular myocytes and vascular endothelial cells. Targeted to the apical membranes of differentiated kidney epithelial cells (By similarity).
Protein: PTH_HISS2
Sequence: MSEIKLIVGLGNPGDKYADTRHNAGEWLIERLARRFNFNLSVESKFSGKTARAVISGQEMRFLVPTTFMNLSGKAVSALANFYRIPPEQILVLHDELDLPPGIAKLKQGGGHGGHNGLKDIIAQLANNKNFYRLRIGIGHPGDKNLVASYVLNKPSPTDWQLIDRTLDEATDCIEILMKEGITKATNRLNAFKA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HASP_BOVIN
Sequence: MAASLPLPASGLFRTYGAAGGGRPRRRQGLAAVQWFPPQDRKRFFSSSSSDTSSGGPSQSVVSDDPDDPDFPGSPVGQRRRRAGARLAKGRPSQIATPRRLRLRSRCPQKCSTPCGALEPPSFPNGNPGSLSPDLRVCGQPRDGGELGTSASLFSSLASPGPGFPAPEDSICTDPSTFLDAASEAPSNFHLPEASLDQAPLPCSQDAATGGGRFTRLAHQAQASLRSALFSFLDPGNPEDSELGTDGKNLQEFCHDRELVGRRLESPGLSGRGKKRTTDQDSCREIESQESVQIEYEEARGCKGGIASGKSNGPERTRLSRKRKHQGTAETSLLHHCQVTKGQKMEDGSCVTQDLTRLQNACSWTKTRASFSFHKKKIVTAVSEVCSCDTLAGSLSESLMSEYSHHPVQNRTSCALSPWHSSSMYLLTPLKTQQVTDKRTSDAEKLYGECNQVGPIPFSDYLSEEKLECCEKIGEGVFGEVFQTVTNHTPVALKIIAIEGQNLVNGAHQKTFEEILPEIIISKELSLLSDEACNRTEGFIGLNSVHCVQGSYPPLLLQAWDHYHSTKGSANDRPDFFREDQLFIVLEFEFGGIDLEQMRKKLSSIATAKSILHQITASLAVAEASLHFEHRDLHWGNVLLKKTSLKELHYTLNGKKSSIPTRGLQVNIIDYTLSRLERDGIVVFCDISRDEDLFMGQGDYQFEIYRLMRKENNNCWGEYHPYNNVLWLHYLTDKILNQMTFKSKHNTPALKRMKKQIQHFYQTMLNFSSATDLLCQHSLFK
What is the function of this protein?
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis.  May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
What are the official names of this protein?
Serine/threonine-protein kinase haspin, Germ cell-specific gene 2 protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Haspin subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis.
Protein: CWC16_SCHPO
Sequence: MQGFNMGKYIPPEGPNAKRKFDKLRNVIRFEMPFPVWCNNCENIIQQGTRFNAVKKEIGSYYTTKIWSFSLKCHLCSNPIDVHTDPKNTEYIVASGGRRKIEPQDINERPAKAENDEKVPSDAIEALETQLTQQKSEKHNSSVINFIYEKNERLWSDPFVSSQRLRKQFRERKKIEKKQEAKDLSLKNRAALDIDILPPSSSDKDKALLLLDNELGKNKFIRKLDYRRTLMPSSRTFSTFAKFAETSFAKKDPFARKFVPSEKLRSEQRKFPTENLKGEKILEDNSVSLVNYEVSDDEG
What is the function of this protein?
May be involved in mRNA splicing.
What are the official names of this protein?
Protein saf4.
What is the protein family that this protein belongs to?
Belongs to the CWC16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNME_RHIME
Sequence: MLSTDTIYALSSGSLPAGVAIIRVSGPETADALVRLCGTLPPPRIATLRTIRTRNGETLDSGLVLYFPTPASFTGEDCCELQVHGGRAVVSAILDELAATGGLRHAEAGEFARRAFQNGKLDLVEVEGLADLIAAETEMQRRLAIEQSGGGQSALYAGWARRLTHSRAMIEAELDFADEDDVPGSVSAVIWEDVGRLRQEIDGHIARAGLAEIIRDGLKIVIAGEPNAGKSSLLNALARRDIAIVTEVAGTTRDVLSVDLSLAGFSVKLFDTAGLRETDELVEREGIRRARQVIADADLVLLLSEKPGHFRIDEVLPENVPVIRVATKVDRPSPSWAPSDADIFLSTRTGEGMADLLTALQSHLPDLAGRTALAMPSRKRHVDCLRQASAALERSLISSDLELRAEQLRQAGDALGRITGRVDVENLLDVIFSEFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOB_HELAH
Sequence: MLICNDNLNQKTLLEEIMALRPWRKGPFEISKIKIDSEWDSSIKWDLVKNATSLKDKIVADVGCNNGYYLFKMLEHGPKSLVGFDPGVLVKKQFEFLAPFFDKEKKIIYKSLGVEDLNEKYPNAFDVIFCLGVLYHRKSPLETLKALYHALKIGGELVLDTLIIDSPLDIALCPKKTYAKMKNAYFIPSISALKGWCERVGFGDFEIISVLKTTPKEQRKTDFILGQSLEDFLDKKDHSKTLEGYDAPLRGYFKMLKSSSKR
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RL35_SACEN
Sequence: MPKNKTHSGTAKRFRVTGSGKLRREQAGRRHILEKKSSRVTRRLEGTEAVAKADVKRINKLLGR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PAND_PSECP
Sequence: MNRTMFKSKIHRATVTHADLHYVGSVTVDLDLLEAADILPGELVSIVDITNGARLETYTIAGERGSGVIGINGAAAHLMHENDLVILITYAQMTTEEAKAYEPKVVHVDQDNRIIQLGNDPAEGIAPGMTRPPFALNNAAL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_CHLCH
Sequence: MKKQVTIYTDGACSGNPGPGGWGALLMFGSITREVSGSSPATTNNRMELGAAIEALALLKEPCLVDLYSDSSYLVNAINNGWLQRWQRNSWQTAAKKSVENIDLWQKLIKLLKVHEVRFHKVKGHSDNAYNNRCDQLAREAIKKTS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_CAUVC
Sequence: MRLDQVRAALDRRLDPASRAPLAVGFSGGGDSLFLLKTVLDWARPLDRPVLALVVDHQLQPQSTAWTAEAVAKARALGAAALGLTWTDQKPRTGLPAAARRARHALLATAAREAGARVLILGHTASDLAEGVAMRAEGSSVSNPRAWAPSPVWPEGRGLFVLRPLLTLTRAEIRDALTREGETWLDDPANLDLRYARARARAAGALTPLLPVRESPPPGVFEIDPAGAIRLPRDVVPAHLAAALLCASGAERPPRGDRLARLVERLRSGARFTATLAGARIEADQAVLICRDAGEAARGGLARLDLAPGACGVWDGRWEVVAGKTALAVVALRGRTSSLPAEQRARLSAIAPAVRPSLPVLLSLDGDAPGELVLDDLQLEADGEARVRSLVPDRFKAAVGLLDQESVT
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTD_PSEPK
Sequence: MTTHYIAGNWQAGQGETLQSLNPVTQAVIWQGQGADASQVDAAVQAARQAFPAWAQLSLEARIDVLEKFAAQLKVHAEAMAQCIGEETGKPLWESATEVTSMINKVAISVQSYRERTGEKSGPLADATAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNCVVFKPSELTPKVAELTVNCWIAAGLPAGVLNLVQGARETGVALAANPGIDGLFFTGSSRTGNLLHQQFAGRPDKILALEMGGNNPLVVDEVKDLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDALIARLVEVCKTITVGAFDEQPAPFMGSVISLQAARALLAAQVELAAKGGVKLLEMTQPQADAALLTPGIVDVTAVADRPDEEFFGPLLQVIRYADFDAAIDEANNTQYGLAAGLLSDSRARYQYFWLRSRAGIVNWNKQLTGAASSAPFGGVGASGNHRASAYYAADYCAYPVASLETASLALPATLTPGVTL
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: DEOC_SHIBS
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQTKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_GEOMG
Sequence: MERTFAIIKPDAVERNIVGKVLEKIEAAGFRIVGMKKIQLSKKEAEGFYYVHSERPFFGDLCSFMSRSPVVVLALERENAIAKWREVMGATNPANADAGTIRKEFGLSIEENTVHGSDSPESAAFEIPYFFSQLELL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_FRATO
Sequence: MFSFYFNDNKITKLLMVGYGSTGKSVCDFLANFIDITVDISQNDDEFVNYDLNSYDLITVSPGIPLNKSPYRALTKFKDKIVSDIDIFYQYIKDTKAKTIAVTGSNGKSTVVTMTDFVLKDLGYKSILVGNIGTPALNKIGEKFDYCVVEVSSFQINLFNCVRFDLGCIINVSPDHLDRYQNFEQYKQSKLNLAKFSNDFFVYDVHNGIKYAGEYQIIRGAIYRNSTKLLDIVETKLFGEHNLENIIVVLNILDRLGLDINQAIDSIKKFKGLEHRCKIVKKVNGTTYINDSKGTNVGATIAALNSITNSKNIILLLGGVAKGGDFSLMIKSLDKYVKYVYIYGADKEYIESYIKGYCKYQLCNNMKQAFELASQKANSNEIVLLSPACASFDEFSGYAQRGEVFQNLVAQLEQKS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.