PharMolix/UniProtQA huggingface dataset:
Protein: BUAB_ASPBU
Sequence: MPGQKPVVLFLTNSEFGQSSVVLAVAQELVRQSACEVHVASFSALKQQVEALNVAFHALPGRSMKEALCDSGLPFLPKHAPGTRGAVESYRKGLQHVVAPWEPAGYEPIYRACLDLLDKLNPDLVAVDPLFGPGQDACNVRQCRYLVLSPASFKDHLVQVQPHLRVLWKYPVISSGLPCPLPLFLIIINFYLIFKLVLHTFLSKRVQTLTKWRNHIGIPGDLTTIYANFNEKVPWLLPSIPQSDFPLKIPTNVTGCGPIIPPFESVAHNPTASWLAQRPTILFNLGSHMKYKLTDAQQVVTALSMVLHTYPDMQILWKCELSHDDPSSKEPESSDSSAIQDLIPAELTDRIRVTSWITPSPMSILAHDSTIMYVHHGGSNSFHEALAAGVAQVVCPVWLDTYDVAARVEFLRVGLRGNGKAAPHLEGSELGAAICRTAHRLRSGDMGTRTRELQAHILAQEEGVSGTGPADVYGVGRRKAAKVILDMITA
What is the function of this protein?
Glycosyltransferase; part of the gene cluster that mediates the biosynthesis of burnettramic acids, an unusual class of bolaamphiphilic pyrrolizidinediones that display potent antibacterial, antifungal, and cytotoxic activities (PubMed:30735051).  The first step of the biosynthesis of burnettramic acids is the hydroxylation of proline by the proline hydroxylase buaE to generate 4-hydroxyproline (PubMed:30735051).  The PKS-NRPS buaA and trans-enoyl reductase buaC construct the highly reduced polyketide chain, and the condensation (C) domain of buaA then catalyzes the amide bond formation with the activated 4-hydroxyproline (PubMed:30735051).  This is followed by the R domain releasing the nascent polyketide-peptide directly via a Dieckmann condensation to afford a tetramic acid fused to the hydroxyproline, generating the bicyclic pyrrolidinedione moiety (PubMed:30735051).  The cytochrome P450 monooxygenases buaD and buaG are likely responsible for the multiple hydroxylations on the polyketide chain and its terminus, although in the heterologous context, buaD does not appear to be required.  Therefore, while buaG may be a multifunctional cytochrome P450 monooxygenase, it cannot be ruled out that the two secondary alcohols on the polyketide chain could have an acetate origin (PubMed:30735051).  Finally, the glycosyltransferase buaB transfers beta-D-mannose to the aglycone burnettramic acid A to form burnettramic acid A (PubMed:30735051).  Burnettramic acid B is a minor cis-pyrrolizidine epimer of burnettramic acid A and it is likely that small amounts of it form naturally in acidic environments (PubMed:30735051).
What are the official names of this protein?
Glycosyltransferase buaB, Burnettramic acids biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DVR1_XENLA
Sequence: MVWLRLWAFLHILAIVTLDPELKRREELFLRSLGFSSKPNPVSPPPVPSILWRIFNQRMGSSIQKKKPDLCFVEEFNVPGSVIRVFPDQGRFIIPYSDDIHPTQCLEKRLFFNISAIEKEERVTMGSGIEVQPEHLLRKGIDLRLYRTLQITLKGMGRSKTSRKLLVAQTFRLLHKSLFFNLTEICQSWQDPLKNLGLVLEIFPKKESSWMSTANDECKDIQTFLYTSLLTVTLNPLRCKRPRRKRSYSKLPFTASNICKKRHLYVEFKDVGWQNWVIAPQGYMANYCYGECPYPLTEILNGSNHAILQTLVHSIEPEDIPLPCCVPTKMSPISMLFYDNNDNVVLRHYENMAVDECGCR
What is the function of this protein?
Serves to facilitate the differentiation of either mesoderm or endoderm either as a cofactor in an instructive signal or by providing permissive environment.
What are the official names of this protein?
Protein DVR-1, Vegetal hemisphere VG1 protein, VG-1.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPIA_STRS2
Sequence: MINLKEQVGIKAAEFVTDGMIVGLGTGSTAYYFVQEIGRRVAEEGLQITGVTTSHATAEHAASLGIPLKNIDEVEYVDLTVDGADEVDGDFNGIKGGGAALLMEKVVAVNSKDCIWIVDESKMVQTLGAFKLPVEVVQYGAENLFRLFEKKGYRPSFRMRNGKKHITDMQNFIIDLDLRRIEDTYALAEELDRTVGVVEHGLFIGLISKVIVGTPEGPNIIEKK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RAB1B_DICDI
Sequence: MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTINLDGKIIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDHVSFNNVKQWMQEIQRYACDSVTRLLVGNKCDLIEKKIVDTSTAREYADSVGIPFLETSAKSSANVEQAFMIMASEIKKLQGGIQPNNNSTYNAHVVKPTGFTPIGKKKKCSII
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  Rab1B regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.  Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum.
What are the official names of this protein?
Ras-related protein Rab-1B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor; Cytoplasmic side. Preautophagosomal structure membrane; Lipid-anchor; Cytoplasmic side.
Protein: RS4_FRAT1
Sequence: MARYLGPKCKLSRREGTDLFLKSGVKANDEKCKMNTAPGQHGARRARLSDYGLQLREKQKVRRMYGILEGQFKKYYVEASRRKGNTGATLLELLESRLDNVVYRMGFAATRAEARQLVVHKGIMVNGHTCNVPSAQVKAGDVVAVREKAKKQLRIQNAVELAKHRKELSWIDVNTDSLEGTMKSSPDRSELSADINEQLIIELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GPMA_STAAN
Sequence: MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PSBM_COFAR
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQNN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AAD6_YEAST
Sequence: MADLFAPAPEPSTELGRLRVLSKSAGIRVSPLILGGMSIGDAWSEILGSMSKERAFELLDAFYEAGGNFIDTANNYQNEQSEAWIGEWMVSRKLRDQIVIATKFTTDYKKYDVGGGKSANYCGNHKRSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEVMDSLHILVQQARSSIWVCLIRLPGLFLRQITTLNLMVKPLLASIKVNGTC
What are the official names of this protein?
Putative aryl-alcohol dehydrogenase AAD6.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: GATC_CHLT2
Sequence: MTESYVNKEEIISLAKNAALELEDAHVEEFVTSMNDVIALMQEVIAIDISDIILEATVHHFVGPEDLREDMVTSDFTQEEFLSNVPVSLGGLVKVPTVIK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RBSD_VIBVY
Sequence: MKKSALLNSELSYLVATLGHTDEITICDAGLPIPDGVSRIDLALTHGVPSFIETVRVMLSESQIEGAIVATEFAEVSPELYQALVAELQCEEEKTGKVLSLTHVSHEEFKQRTESSKAVVRTGECTPYANVIFQAGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_STRS7
Sequence: MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGLKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVAAVSSRSEKVGDYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFILITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGAGSSEAIANRVNLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKLRIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQIAYNAGYEGSVIIDKLKNSAAGVGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVAGLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEC10_CAEEL
Sequence: MNRNPRMSKFQPNPRSRSRFQDETDLRSLRSFKTDFSNYLASDTNFLNVAEIMTSYAYGESNNAHEKEIQCDLLTENGGIEIDPTRLSYRERIRWHLQQFCYKTSSHGIPMLGQAPNSLYRAAWVFLLLICAIQFINQAVAVIQKYQKMDKITDIQLKFDTAPFPAITLCNLNPYKDSVIRSHDSISKILGVFKSVMKKAGDSSSEALEEEEETEYDMNGITIQAKRKKRGAGEKGTFEPANSACECDEEDGSNECEERSTEKPSGDNDMCICAFDRQTNDAWPCHRKEQWTNTTCQTCDEHYLCSKKAKKGTKRSELKKEPCICESKGLFCIKHEHAAMVLNLWEYFGDSEDFSEISTEEREALGFGNMTDEVAIVTKAKENIIFAMSALSEEQRILMSQAKHNLIHKCSFNGKPCDIDQDFELVADPTFGNCFVFNHDREIFKSSVRAGPQYGLRVMLFVNASDYLPTSEAVGIRLTIHDKDDFPFPDTFGYSAPTGYISSFGMRMKKMSRLPAPYGDCVEDGATSNYIYKGYAYSTEGCYRTCFQELIIDRCGCSDPRFPSIGGVQPCQVFNKNHRECLEKHTHQIGEIHGSFKCRCQQPCNQTIYTTSYSEAIWPSQALNISLGQCEKEAEECNEEYKENAAMLEVFYEALNFEVLSESEAYGIVKMMADFGGHLGLWSGVSVMTCCEFVCLAFELIYMAIAHHINQQRIRRRENAANEY
What is the function of this protein?
Subunit of an amiloride-sensitive cation channel (degenerin channel complex) permeable for sodium, potassium, lithium and N-methylglucamine, and required for mechanosensory transduction (touch sensitivity) (PubMed:11875573, PubMed:17261841, PubMed:7509039, PubMed:12478294).  Negatively regulates the turning step of male mating behavior (PubMed:17611271).
What are the official names of this protein?
Degenerin mec-10, Mechanosensory abnormality protein 10.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYDND_METHJ
Sequence: MRVPINTITPDTPSAEVIGWAHEIRDLGGLAFLLIRDRTGIIQVTVPKKKVAPEIAETIRAISRESVVRVTGTVKPEGKAPGGRELIPDAIEIVSLSATPLPLDVAEKVPAELDTRLDNRFLDARRPRVSAIFKIRNAVQHATRNFFFENGFIEINTSKIVAAATEGGTELFPIAYFEKEAFLNQSPQLYKQMMMAAGFEKVYEIGPIFRAEEHNTTKHLNEATSIDIEVSFTDHLGVMQTLEDLIRDIYQFVDKTCSDAIADLGLDDFAVPEKGFPRLPYSEAIEIASATCEEDIAYGDDIGTAAERAIGEEMGRLYFIVDWPSSIRPYYAMPYENDPEICKAFDMMHPRMELSSGAQRVHQHDLLVEQIAKKGLNPENFEFYLNPFRFGMPPHAGWGLGAERLVTTMLGLPNVREAVLFPRDRHRVVP
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_RHOPS
Sequence: MASRDSANADITPEVLLRAYACGIFPMAESIDDPTLFWVEPELRGIIPLGGFRVASRLARTVRSDVFTVTVNRDFRGVIDGCASPQPGRDDTWINRRIRELYIGLHGIGHCHSVEVWQDDDLVGGLYGVSLGRAFFGESMFHRARDASKVALVHLVARLLAGGYELLDTQFVTEHLRSFGAIEVPRQRYRALLDDALHGVADFGALPVDQPVSGAQALEIIAKN
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_BORHD
Sequence: MIDSILFDLIEREVKREKENIELIASENFVSSDVRRAVGSILTNKYAEGYPSKRYYGGCFVVDDIESLAISRARELFGANYANVQPHSGSQANMAAIMALIKPGDRILGMELSHGGHLTHGSKVSFSGMFFDAYSYGVSRESEMIDYDDVRKIAKECRPNLIIAGASSYSREIDFKKFREIADEVSAYLLCDVAHTAGLIATGFHNSPIDVAHLTTSTTHKTLRGPRGGLILAGRESSIIVNYNNKERRLEDAVNSCVFPGTQGGPLMHVIAGKAVAFREALMEDFKDYISRVISNTKAMAECFISEGFRIVSGGTDNHLFLVDLGILGITGADAEKVLERVNITLNKNAIPFDSKNPSVTSGIRIGAAAITSRGLNRDDSIRVAHFVIRALKTKSEDELKKIKRDVIEFISSFDMP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG4D_HUMAN
Sequence: MNSVSPAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEPDEVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPPELSGSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSGKKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKSVVILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATERYPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL
What is the function of this protein?
Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis.  The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
What are the official names of this protein?
Cysteine protease ATG4D, AUT-like 4 cysteine endopeptidase, Autophagy-related cysteine endopeptidase 4, Autophagin-4, Autophagy-related protein 4 homolog D, HsAPG4D.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
[Cysteine protease ATG4D]: Cytoplasm. SUBCELLULAR LOCATION: [Cysteine protease ATG4D, mitochondrial]: Cytoplasm. Mitochondrion matrix. Note=Imported into mitochondrial matrix after cleavage by CASP3 during oxidative stress and cell death.
Protein: Y082_VIBPA
Sequence: MVRWMFIFLALALVSAVLGFSGIAGAAAAVAQVIFYLFLLSLIVSIVFVILGKKNVNR
What are the official names of this protein?
UPF0391 membrane protein VP0082.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL7_ALIFM
Sequence: MSITNEQILDAVAEMSVMQVVELIEAMEEKFGVTAAAAVVAGGAAGGDAAEEQSEFDVILTSAGANKVAVIKAVRGATGLGLKEAKGLVDSAPAPLKEGVDKAEAEALKAQLEEAGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: HSP74_TRYBB
Sequence: MTYEGAIGIDLGTTYSCVGVWQNERVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPTNTVFDAKRLIGRKFSDSVVQSDMKHWPFKVVTKGDDKPVIQVQFRGETKTFNPEEISSMVLLKMKEVAESYLGKQVAKAVVTVPAYFNDSQRQATKDAGTIAGLEVLRIINEPTAAAIAYGLDKADEGKERNVLIFDLGGGTFDVTLLTIDGGIFEVKATNGDTHLGGEDFDNRLVAHFTEEFKRKNKGKDLSSNLRALRRLRTACERAKRTLSSAAQATIEIDALFENIDFQATITRARFEELCGDLFRGTLQPVERVLQDAKMDKRAVHDVVLVGGSTRIPKVMQLVSDFFGGKELNKSINPDEAVXYGAAVQAFILTGGKSKQTEGLLLLDVAPLTLGIETAGGVMTALIKRNTTIPTKKSQIFSTYSDNQPGVHIQVFEGERTMTKDCHLLGTFDLSGIPPAPRGVPQIEVTFDLDANGILSVSAEEKGTGKRNQIVITNDKGRLSKADIERMVSDAAKYEAEDKAHVXXIDAKNGLENYAFSMKNTINDPNVAGKLDDADKNAVTTAVEEALRWLNDNQEASLEEYNHRQKELEGVCAPILSKMYQGMGGGDGPGGMPEGMPGGMPGGMPGGMGGGMGGAAASSGPKVEEVD
What are the official names of this protein?
Heat shock 70 kDa protein 4, HSP70-4.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RIBBA_MYCA1
Sequence: MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPTSIAEDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFADEHDLAMITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYTSIYEEVEHVALVRGEIAGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMRGHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGFPADARDYGIGAQILVDLGVRSMRLLTNNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKMGHDLAGLDDFHESVHLPGEFGGAL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: LEPA_CHLTE
Sequence: MPPTGTEVGMIRNFCIIAHIDHGKSTLADRLLEVTHTLERNQMSTAQVLDDMDLERERGITIKSHAVQMRYTAKDGQDYILNLIDTPGHVDFSYEVSRSLAACEGALLVVDATQGVEAQTIANLYLAIEAGLEIIPVINKIDLPSSDVEGVARQIIDLIGVNRDEILRVSAKNGIGVDDLMEAIVARVPAPADNRQMPLRALIFDSVFDAYRGAIAYIRIVDGVLKKGDRVRFFANDKIFMADEIGTMSLKRNPVDILEAGNVGYLICSIKDVKDAKVGDTVTLVENPAAERLAGYKDVKPMVFSGLYPVESNEFEDLRESLEKLSLNDASLVYTPETSAALGFGFRCGFLGLLHMEIIQERLEREYGVNIITTVPNVEYRVIMTSGETVEVDNPSKMPETTKINWIEEPYVSMQIITMSEYIGNIMKLGMERRGEYKNTDYLDTSRVNIHFEFPLGEVVFDFHDKLKSISKGYASMDYEYIGYRRSDLVKLDVLLNGEPVDALSSIVHRSKSYEWGRKLCQKLKGIIPRQMYEVAIQAAIGSRVIARESISAMRKNVLAKCYGGDISRKRKLLEKQKEGKKRMKQVGRVEVPQEAFLAVLNIDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DHAR4_ARATH
Sequence: MGIEVCVKAASGAPDVLGDCPFGQRILLTLEDKKLPYKTHLIDVSLKPDWFLAISPKGKLPLVKFDEDENWVADSDLIVGIIEEKYPEPSLVTFPPEFASVGSKIIGAFVMFLTSKDHANDGSDMALLDELEALDHHLKTHVGPFVAGDKVTVVDLSLAPKLYHLETTLGHFMDWCVPESLTNVRDYMKVLFSLESFEKTKAAKEYLIASWAPKLDV
What is the function of this protein?
Exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities.
What are the official names of this protein?
Probable glutathione S-transferase DHAR4, Chloride intracellular channel homolog 4, CLIC homolog 4, Glutathione-dependent dehydroascorbate reductase 4, AtDHAR4, GSH-dependent dehydroascorbate reductase 4.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. DHAR family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MNS1_BOVIN
Sequence: MASIRRTLSFSERHQKLVDINYCKKLHVEALQRLQNQTRDQMVQNENDDRAERKRFLRLLQDEQFELDMEEAIQKAEENKRLRELQLAQEEKLATELAKLKRESLKDEKLRQQVRENSAELRELEKKLKAAYMNKERAAQIAEKDAIKYGQMKRDAEIARTMMEEHERLIKEESAAEDKRNQAKAQYSHDLEKQLEEQGKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLERQQRLEKMNTTRRYIEEFQKEQALWRKKKREEMEEENRKIIEFAKLQQQREEDRMAKVQEKVKKKRLQLKNMLTQRLEEMLRQREDLEQVRQELYQEEQAEIYKKKLEEEAEEKLRKQKELKQDFMDQMALKELILQAAKEEEETFRKAMLAKFAEDDRIELMNAQKPRMKQLEHKRAVEKLIEERRNQFLADKQRELEEWQWQQRRQGCINAIVEEERLKLLKEHATKLLGYLPKGVFKNEDDIDMLGEEFRKAYQKRSEICEK
What is the function of this protein?
May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity).  Required for sperm flagella assembly (By similarity).  May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC).  ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules (By similarity).
What are the official names of this protein?
Meiosis-specific nuclear structural protein 1.
What is the protein family that this protein belongs to?
Belongs to the MNS1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme.
Protein: ATPD_MAGSA
Sequence: MPSETIGVIADRYATALFELADSSGSLDQVAGDLKTLQAMLRESADLRRVVDSPVLSRNDQGKAISAVAKAAGFSELTNKFLGLAAQNRRLHTLSGVIASYLGRLAARRGEKSATVASAVALSPAQQDALTTALKAAFGGNVAVDVKVDPSLLGGLVVQVGSRMVDSSLKTKLQHLKLAMKGVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PUR5_SHESH
Sequence: MSTPTQLSYKDAGVDIDAGNALVDNIKTAVKRTHRPEIMGNLGGFGALCELPTKYKHPVLVSGTDGVGTKLRLAIDHKKHDTVGIDLVAMCSNDLIVSGAEPLFFLDYYATGKLDVEAATSVVKGIAEGCVQSGCALIGGETAEMPGMYEGDDYDLAGFCVGVVEKADIIDGSKVVAGDSLIALASSGPHSNGFSLIRKVLEVSEADPQLNLEGKPLIDHLLEPTKIYVKSLLKLLEQTDVHAMAHITGGGFWENIPRVLPEDCKAVVKGDSWQWPTVFNWLMENGNIAEFEMYRTFNCGVGMVVALPSEKVDAALTLLNAEGENAWLIGDIAKRNGDEEQVEIL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.