PharMolix/UniProtQA huggingface dataset:
Protein: 6PGL_YERPY
Sequence: MKQAVYVASPDSQQIHVWQLDSAGELTLLQTVDVPGQVQPMAISPNQRHLYVGVRPDFGIVSYHIADDGTLTAAGMAPLPGSPTHIDTDRQGRFLFSASYSFNCVSISPIDTHGVVQAPIQQLDDLPAPHSANIDPTNQILLVPCLKEDKVRLFDLSAEGQLTPHAQADITVAAGAGPRHMAFHPNHQVAYCVNELNSSVDVYQISNNGQEYHLVQSLDAMPADFTGTRWAADIHITPNGRYLYISDRTANLLGIFTVSKDGRVISLVGHHLTEAQPRGFNIDHSGNFLIASGQKSDHIEVYRIDQNTGELTTLKRYPVGKGPMWVSIRGAQNS
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: Y3148_PARPJ
Sequence: MAEDATLVDETALEAAAGESPPSNATACGELAPSPLLRGKWLKDDMPRERLLRQGPGVLSDTEMIVLILGSGLPGHDVFSVARELLDRFGSLRAMLDATYTDFDGLRGIGPAKKAQLLAIMEMARRSLVDKLRSRSLLNSPEAVENYLRLRIGGRPLEVFVSLFLDARHRLIHCEESAQGTLTRMAVYPREIVRRALSLNAASLIVAHNHPSGAVQPSASDCRLTHTLRDALTLIDVQLVDHLVVGVDSVYSFARAGWP
What are the official names of this protein?
UPF0758 protein Bphyt_3148.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: PUR5_BURA4
Sequence: MNPPKSAPDAQGLSYRDAGVDIDAGDALIDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYKEPVLVSGTDGVGTKLKLAFHLNKHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVDTAATVVKGIAHGCELSGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSKIIDGSTIAEGDVVLGLASSGIHSNGFSLVRKIIERANPDLSADFHGRSLADTLMAPTRIYVKPLLALMQKLPVKGMAHITGGGLVENIPRVLREGLTAELDQNAWPLPPLFKWLQEHGGVADAEMHRVFNCGIGMAVIVSAADADAAIADLTAAGEQVWKIGTVRASREGEAQTVVA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_PORGI
Sequence: MLEKLIILDFGSQTTQLIARRIRELNTYCEVYPYNKLPEDLSGVRGIILSGSPYSVYDSKAFRIELSELRGKLPLLGICYGAQSLVHQAGGKVEPCDSREYGRTHLTLRQPDDALLTGLQSGTTVWMSHGDTITSLPEGFEVIAGTEDVPNAAFRIRGEKTWGVQFHPEIYHSEEGTKLLGNFLDICGMKRDWTPASFIEATVQELRERLGDDKVILALSGGVDSSVVAVLLNKAIGRNLTCIFVDHGLLRKGEFERVLQDYEHLGLNVIGVNAKEKFFAALSGVTDPEQKRKIIGRGFIEVFDEEARKLKDIKWLGQGTIYPDVIESLSITGMVIKSHHNVGGLPERMNLRLVEPLRMLFKDEVRRVGLELGMMPHLIHRHPFPGPGLGIRILGEITEEKATILQNADDIYMSLMREWGLYDQVWQAGAILLPVRSVGVMGDERTYEYTVALRAVTSMDAMSADWVHLPYDFLAKVSNEIINKVRGVNRVVYDISSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: CDPAS_METBF
Sequence: MLPAYLSNPFAAVFGGGKPIDGGRTYKDGRRILGDGKTYRGLFSGIFCGFIAGCIEIWLSSRGFEIMGINMPVFGPDYKSALIVVLALASGALFGDMFKSFFKRRMGLKRGASLPLVDQLDFVVGAWVFTYLVAPEWFVSNFTHGIMLTVIIITPLLHLTTNIIGYLIGVKKEPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACA7_ORYSJ
Sequence: MECADYFIGSGRRCSPSTSTSTSREAWRPEKQWRKATNVIRGCHRLLRLGVLSAAAGIMRRNPSYVEIKVHDEGELDVSSGGDGEAPVAFTVAADDESFKGLVKNKREDCFRLLGGGAGVAAVLASGAERGIRGDDADVARRKKAFGSNTYPKPKPKGFFRHVWDALADVFLIVLLVCAAVSLAFGIKEHGIKDGWYDGVSIFLAVFLVAAVSAVSNHSQGKRFDKLARESENIMVSVVRAARRQEVSIFDVVVGDVVVLKIGDVVPADGVFLDGHALQVDESSMTGEPHPVEVDAVKSPFLASGVKVVDGYGKMVVTAVGTDTAWGEMMRTITRENTDPTPLQERLEGLTSSIGKVGIAVAVLVFAVLTARHFTGSTRDEQGNALFDKRNVTFNAVFSGLVGIFQQAVTIIVVAIPEGLPLAVTLTLAFSMKRMVRENALVRRLSACETMGSVTAICTDKTGTLTLNQMKVTEFWVGADRPRSAAAVNGGVVRLLCQGAGLNTTGSVYKPDNVSPPEITGSPTEKALLSWAVEELPMDADALKRKCKVVRVEAFNSDKKRSGVMLRDAATGAVTAHWKGAAEMVLARCTVYVGADGAARELGVEQRRKLEQVINDMAAASLRCIAFAYKQVVDGGDSDNAKIDDEGLTLLGFVGLKDPCRPEVKSAIEACTKAGIAVKMVTGDNVLTARAIAKECGIISGNDDDAAGVVIEGHEFRAMSEQEQLAIVDNIRVMARSLPLDKLVLVQRLKQKGHVVAVTGDGTNDAPALKEADVGLSMGVQGTEVAKESSDIVILNDNFDTVVTATRWGRCVYNNIQKFIQFQLTVNVAALVINFVSAVTTGRMPLTTVQLLWVNLIMDTMGALALATDTPTAGLMRRPPIGRAAPLISNAMWRNLAAQAAYQVAVLLALQYRGFGGAGAGERANGTMIFNAFVLCQVFNEFNAREIERRNVFAGVHRNRMFLGIVAVTVALQVVMVELLTKFAGTERLGWGQWGACVGIAAVSWPIGWAVKCIPVPERPFHEIITARRRRRRST
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell, into the endoplasmic reticulum, or into organelles (By similarity).  Involved in salt stress tolerance (PubMed:24286292).
What are the official names of this protein?
Calcium-transporting ATPase 7, plasma membrane-type, OsACA7, Ca(2+)-ATPase isoform 7.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: URED_BURP6
Sequence: MSAHEPHTSLVRPAAKAWHARLELGFERQPGGRTALAHRRHVGPLRVQRALYPEGDAICHAVIVHPPGGVAGGDRLEIDVRLDAGTHAVLTTPGATKWYKSNGLDARQRIDIDVGAHAKLDWLPQNNLFFDAAHASLEFVLALGDGASVLGWDATQLGRQAAGEAWSAGSIASFSKIVGPSGRPLWVERARLDAGDPLRAAPQGLGGFAVYGTLWALGAACTEALAESIAPALPFDDALRAGVTCVAPGTLLIRALAHSMEALQRLLAEQWLALRPIVHGVDPKPLRLWQT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKSA_METJA
Sequence: MTKVLVMFMDFLFENSWKAVCPYNPKLDLKDIYIYDTTLRDGEQTPGVCFTKEQKLEIARKLDELGLKQIEAGFPIVSEREADIVKTIANEGLNADILALCRALKKDIDKAIECDVDGIITFIATSPLHLKYKFNNKSLDEILEMGVEAVEYAKEHGLFVAFSAEDATRTPIEDLIKVHKAAEEAGADRVHIADTTGCATPQSMEFICKTLKENLKKAHIGVHCHNDFGFAVINSIYGLIGGAKAVSTTVNGIGERAGNAALEELIMALTVLYDVDLGLNLEVLPELCRMVEEYSGIKMPKNKPIVGELVFAHESGIHVDAVIENPLTYEPFLPEKIGLKRNILLGKHSGCRAVAYKLKLMGIDYDREMLCEIVKKVKEIREEGKFITDEVFKEIVEEVLRKRNKN
What is the function of this protein?
Catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form (R)-homocitrate.  Can also catalyze the condensation of alpha-ketoadipate with acetyl-CoA to form (R)-homo(2)citrate, and the condensation of alpha-ketopimelate with acetyl-CoA to form (R)-homo(3)citrate.  These reactions are part of the biosynthesis pathway of coenzyme B and biotin.
What are the official names of this protein?
Homocitrate synthase AksA, (R)-homo(2)citrate synthase, (R)-homo(3)citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: ACBD6_DICDI
Sequence: MTDAQIENKFKLAVDYITNNSGKLSNIKNEEQLYLYCNYKQATIGDCNTKAPPFYDYIGKSKWNSWNSLKGVEKIVAMNSYISLVNALSPGWDSNIKVERATQSVFLNDEEFKELEKKEKEEKEELKKLEEENGGEIEKPKSKWMGPVLSKFSLVDDETLEKLEKNTKQDLGYWVSVNDIERVKKEIENDKNIINEVDEDGRTALIWACDRGYFEIAKLLIENGSNVNVQDGEGMTPLHYAVVCDQFEICKLLLSQSSIDKSIKDNSDSIPSDFIDSSTSENIKSLFK
What is the function of this protein?
Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA.  Does not bind fatty acids (By similarity).
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 6 homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YABA_STRPM
Sequence: MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLENTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRELLDRK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: SEY1_TRYB2
Sequence: MAAFSGETAVKGIHLINDDGELLPEADINDFLISALAGKGSSDILYRTGVNYHVVGVFGGQSSGKSTLLNSLFQTEFMTMDEAHHRGQTTKGAFMTRAILDAQTHRKEREEGEGADLLKREKPQPLFVLDFEGTDGIERGEDQNFERQLSLFALSVADILIINMWAVDVGRFNAANMNLLRTVFEVNLQLFSHGSYVKEEKPTLLVVLRDFTENDPAPSFETVRKSFDKIWGNIQKPESFTDATIDVVFDLRYRVLPHYKLQRPEFDSAVSEFREWFVSPKNSNFLFSNCSMFRGVPADGMPSYLSNCWNAICSSKDLDIPTQRDMLARHRCADAKHAAIEEFKEVCEEYTKKIQRGDVIPQFTRALEETIERLLKNFSDQTKLYKVSVVHETAEALEEELGDMELHLLKQYAKSIAVTVLAALDGVIGSSVDEAVRWLQNEARSVLLLEGKDNKGDRIDGGGLAQGVLDTAEGLVDNKRCRLFVEEFWKRICLSLQGAFDMLNGCSKSHQAALSSLYGKFATAIMDDQAVREGVAHAAMEGAQHKLRNRFVAMAENAAETVHQVFEQALTSKTDGTVRFFRTTDGLLGAEKQARQAGLVLLGCLLYYRLKLVPVEVDAGEVEGEGTTRALQRLVRDRCRFQVRDNRTEKNFFLHFTNISDVPRYPLDAPTSVVDSGDTTADTVNADNVLLSHNALQCAFHLYKQKADFTLQMQLRNIESGKQSLPPWVLPVMLLLGWNELYYLLTSPILLIAIIVIAVLFFKTFLKSQLEVLEEKCPVWLVVSVKALLQQAQALQNAYAPTEAVRGGGGGAQFRDPTQATSVSGASAGVSSESSSAASPRRRVCRESRDKGED
What is the function of this protein?
Probable GTP-binding protein that may be involved in cell development.
What are the official names of this protein?
Protein SEY1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GB_GAHVR
Sequence: MHYFRRNCIFFLIVILYGTNSSPSTQNVTSREVVSSVQLSEEESTFYLCPPPVGSTVIRLEPPRKCPEPRKATEWGEGIAILFKENISPYKFKVTLYYKNIIQTTTWTGTTYRQITNRYTDRTPVSIEEITDLIDGKGRCSSKARYLRNNVYVEAFDRDAGEKQVLLKPSKFNTPESRAWHTTNETYTVWGSPWIYRTGTSVNCIVEEMDARSVFPYSYFAMANGDIANISPFYGLSPPEAAAEPMGYPQDNFKQLDSYFSMDLDKRRKASLPVKRNFLITSHFTVGWDWAPKTTRVCSMTKWKEVTEMLRATVNGRYRFMARELSATFISNTTEFDPNRIILGQCIKREAEAAIEQIFRTKYNDSHVKVGHVQYFLALGGFIVAYQPVLSKSLAHMYLRELMRDNRTDEMLDLVNNKHAIYKKNATSLSRLRRDIRNAPNRKITLDDTTAIKSTSSVQFAMLQFLYDHIQTHINDMFSRIATAWCELQNRELVLWHEGIKINPSATASATLGRRVAAKMLGDVAAVSSCTAIDAESVTLQNSMRVITSTNTCYSRPLVLFSYGENQGNIQGQLGENNELLPTLEAVEPCSANHRRYFLFGSGYALFENYNFVKMVDAADIQIASTFVELNLTLLEDREILPLSVYTKEELRDVGVLDYAEVARRNQLHELKFYDINKVIEVDTNYAFMNGLAELFNGMGQVGQAIGKVVVGAAGAIVSTISGVSAFMSNPFGALAIGLIIIAGLVAAFLAYRYVNKLKSNPMKALYPMTTEVLKAQATRELHGEESDDLERTSIDERKLEEAREMIKYMALVSAEERHEKKLRRKRRGTTAVLSDHLAKMRIKNSNPKYDKLPTTYSDSEDDAV
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: PYRC_ACIB5
Sequence: MNSITLLQPDDWHAHLRDGLALKRTVPDLAKQFARAICMPNLVPPVKTVEEALAYRERILAHVPEGNNFDPRMVLYFTDHTSPDEVRKIKESEHVNAIKLYPAGATTNSDNGVSDIRKVYAVIEQLEEHQVPLLLHGEVTHNHVDIFDREKRFLDEVLSPLLKQFPKLKVVLEHITTSDAAHFVLEQDRNVAATITPQHLLFNRNDMLVGGIKPHFYCLPILKRQTHQTTLLEVATSGNPKFFLGTDSAPHAQNAKENACGCAGCYSAPNAIELYAQAFDQVGKLERLEGFASHFGADFYGLPRNTSTITLVKEDNLVPESFDYLDNQKIIPLHAGKTLQWRKV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: FADI_YERPP
Sequence: MSKPLPLVTRQGDRIVIVNGLRTPFAKQATAYHGVPAVDLGKIVVSELLARSGISSELIDQLVFGQVVQMPEAPNIAREIVLGTGMSVHTDAYSVSRACATSFQAVANVAESIIAGSVDIAIAGGADSSSVLPIGVSKALARTLVDANKARSLSQKLKLFSRLRLRDLLPVAPAVAEYSTGLRMGDTAEQMAKTYGISREDQDALALRSHQLAAEAWQQGWLHDEVMTAYIPPYREAIIEDNNIRKDSTLAQYAKLRPAFDRQHGSVTAANSTPLTDGAAAVLMMSESKAKALGLPPLGYLRSFAFSAIDVWQDMLLGPSYATPLALDRAGITLADLTLIDMHEAFAAQTLANLKMFASDTFAREKLGRSQAIGEVDMSKFNVLGGSIAYGHPFAATGARMITQTLNELRRRGGGLGLTTACAAGGLGAAMILEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_SCOJU
Sequence: MTILRKSHPLLKIINHSLIDLPTPSNISSWWNFGSLLGICLMIQIITGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYIHANGASMFFICLFIHVGRGIYYGXXMLNETWNIGIILFLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYVGTTLVEWIWGGFSVDKATLTRFFTFHFILPFIITALVLVHLLFLHETGSNNPSGLNSNADKIPFHPYYTIKDLLGIFMLLLALMTLVLFFPDILGDPDNYIPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILAAFPLLNTSKQHGLMYRPITQTLYWIFIANLFILTWIGGQPVEHPFIMIGQISSILYFTIIVILMPMASMIENNVLKLHV
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UPP_THEGJ
Sequence: MRRDERWDGVYSFEDSPFIMEILTELRDKNTDSIAFRKGLVKLGRYMGYELTKTMDVEEIEVETPLEKTRGILVKDRRNVVIITVLRAAIPLMEGLIKVFEHARVGIVSASRGKAPKFEIEMNYIKIPTVKPDDTVIVADPMIATGSTLIRVLKEVSKYGRPKRLIILGVLAAPEGISRIKEAFPEAEIFVAKVDRELNEKGYILPGLGDAGDRAFGAPLKSPR
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PYRD_ANASK
Sequence: MLWPALRSVLFQLDPERVHHLAHWALHRVPLAVARARRPAPIPALAVRCMGLDFDGPVGLAAGFDKGDVALPGLFGLGFSHVEIGTITPRPQPGNDRPRLFRLPEHRALLNRMGFNNEGMEACARRLAALPPAARLGPVGINVGKNKVTPNEDAAADYLACIERLHPYADYLVVNISSPNTPGLRQLQERDALDRLLRACVRHLAERAPGKPLLVKLAPDLSPEALDEAVDVAIAAGAAGIVATNTTLSRAGVERHPRAAEAGGLSGAPLERLATDVVRRCYARAAGRVPIVGVGGVMDAEGAYAKIRAGATLVQAYTGLIYGGPGFVGRVNAGLARLLERDEFSTLSDAIGADHRQGGGKAAG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MDTB_ECOSE
Sequence: MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTEITPGLAALDTIRLTSSDGGVVPLSSIAKVEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y7786_DICDI
Sequence: MDAQIKNEIVELTKAMLETFTKEYIKAYTIQITKKAIKDAKAIPSPYLLEPRPRDHDKSDVFSGYLVKLGAIRKNWLKRHFVVRYDYSIDYFVDDKHTNKKGTINLCGYSVNDDPNKSGLDRILKIAEKMGVDTSSIPKPAQLPPFTIELYHYSRRCYYIQCANEEEFKEWIEIFKTCCRRSHGFKNKDPCHIAAFGIAVRNTRWSLGRWGWFGYGGNENQILSDIILDEIEYDILGRALSKLPNAPWFIRNYLRNKMMTVIEGMVSSAVAPAWTGLSKTVEELRPTIEPRIKNQVDPIAQAQTNIINKMRESMMSQIKPAMEEHVNKHLKKIIGEIRTPIENGFDESLKIWNEKTNAYNGNGSTESFSSYRSYPNSYWTMYPAKDKISPLYSIVEEYRPIFRDYSSYFICYDIKESINNMAYDGAYTLEKTVTQDQVDVASAKNQTHSKYQHDVILGTNMQLKFVVREMVKPTLCKIINPLTKPLLNTLSSSIPSAIGDFIDINELYNQLVDDILNDSTQVVIDELN
What are the official names of this protein?
PH domain-containing protein DDB_G0267786.
Protein: RIHC_ECOUT
Sequence: MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEKTTRNALQLLHFWNVDIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRQPLGIPAFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTPNAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALFSHYRSGSMQSGLRMHDLCAIAWLVRPELFTLKPCFVAVETQGEFTSGTTVVDIDGCLGKPANVQVALDLDVKGFQQWVAEVLALAL
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: PURA_PSYCK
Sequence: MGKNVVVLGSQWGDEGKGKIVDLLTEKASAVARFQGGHNAGHTLVVDGKTTVLHLIPSGILREGVTCFIGNGVVLAPDALLKEMKGLEENGVPVRERLRISPNCPLIMPYHVALDQAREAKRGSGKIGTTGRGIGPAYEDKVARRAIKLADLFRDDLEEKLRNLIEYHNFQLTQYYKVEAIDFDETLKLCKEWKEEIRGMVTDVTEDLNQLRLAGKNLMFEGAQGTLLDIDHGTYPFVTSSSVTAGGVSTGTGIGPLYLDYVLGITKAYTTRVGSGPFPTELFDDVGAHLAKVGHEFGATTGRARRCGWFDAEALRRAVVLNSMSGICLTKLDVLDGLEELLIGVGYNLPETECAGAHDAEFYEAVTPKYETLQGWSESTVGITNYDELPENAKIYIKRIEALIGCPVDIISTGPDREETIVLRDPYDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBP_BHV1C
Sequence: MTATPGAAADAVRVEGAGACSDGGEEARYASSASLARMLYGADLSERVRRRHPAVCVEHQSGRPVALPSPLAADARRVTVVRAPMGSGKTTALLRWLGEALGATDASVLVVSCRRSFTRTLHERLRDAALPAFATYFDARSYVMTGAAYRRLLVQVESLHRVDEELLGDYDILVLDEVMSTLAQLYSPTMGRLHRVDALLHRLLRRCPRIVAMDATVNAQLVDLLAALRGAGSVHVVICDYASAGFLQRRCTVARRLGARVLAARLKGDAEDGAEDGGASFFTRLRARLEAGHNVCVFSSTVLFSELAARFCLTFTPSVLVLNSTRPAEGDVSRWRDVRVLIYTTVITVGLSFDHSYFHAMFAYVKPMSHGPDMVSVYQSLGRIRSLVDNELCVYFDSSAARPEPVFTPMLLNHVVAEDGGWPATFSEVTNLLCCSFRAACAPAFRGARGLALFPRFKYKHLFERCTLASASDSLNILHALLENNRVGFQLEALRSAHRRGILPLSRGRARRRPAAAADLRALAAGIPSPVSAEGLAEHPAVAAFADKYLRAGGAPPAALEELLRALNGPAARARFVNLAVLGGCLHVPAAAESLEVFAGIYRHYASGEVPVLTEAGAVETAALAPGLRWKPTALFGLRRMARALGLLRRRGGGEADDVADAAHGLTEPAIVELVGPPGGHDYAQCLLEIARCNITPAGVMARGPVVAVAARLSGRGFAQGRGVGLGAAAHAVSVFKVIWEEVFGARLQKSTQTFPGHARVKNLRKHEIVALLDLAGIDRAGRDTHRELYRLLMSHKARFASPKYSLRLPKWGRLLGFAARGPEPGPDAPPEASLEAALARVPALHWPCAAGAVDFCAL
What is the function of this protein?
Functions as a docking protein to recruit essential components of the viral replication machinery to viral DNA origins.  In the presence of the major DNA-binding protein, opens dsDNA leading to a conformational change in the origin that facilitates DNA unwinding and subsequent replication (By similarity).
What are the official names of this protein?
Replication origin-binding protein, OriBP, OBP.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae OriBP family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PYRC_AQUAE
Sequence: MLKLIVKNGYVIDPSQNLEGEFDILVENGKIKKIDKNILVPEAEIIDAKGLIVCPGFIDIHVHLRDPGQTYKEDIESGSRCAVAGGFTTIVCMPNTNPPIDNTTVVNYILQKSKSVGLCRVLPTGTITKGRKGKEIADFYSLKEAGCVAFTDDGSPVMDSSVMRKALELASQLGVPIMDHCEDDKLAYGVINEGEVSALLGLSSRAPEAEEIQIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHLLFTEREVLNSGANARVNPPLRKKEDRLALIEGVKRGIIDCFATDHAPHQTFEKELVEFAMPGIIGLQTALPSALELYRKGIISLKKLIEMFTINPARIIGVDLGTLKLGSPADITIFDPNKEWILNEETNLSKSRNTPLWGKVLKGKVIYTIKDGKMVYKD
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: DTD_BACC3
Sequence: MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHVETGEFGAMMDVSLINDGPVTLIVESK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B3GT1_HUMAN
Sequence: MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVARKNFTFGNIRTRPINPHSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWGDENNFKGIKIATLFLLGKNADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDIFVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTGYIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLGIHPFQNSGFNHWKMAYSLCRYRRVITVHQISPEEMHRIWNDMSSKKHLRC
What is the function of this protein?
Beta-1,3-galactosyltransferase that transfers galactose from UDP-alpha-D-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue.  Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins.  Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.
What are the official names of this protein?
Beta-1,3-galactosyltransferase 1, Beta-1,3-GalTase 1, Beta3Gal-T1, Beta3GalT1, UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.