PharMolix/UniProtQA huggingface dataset:
Protein: GLPK_CLOBA
Sequence: MGKYVVALDQGTTSSRAIIFDKEQNIVGVSQKEFTQIYPHEGWVEHNPLEIWSSQYGVLQEVLAKTNITADEISAIGITNQRETTIVWDKNTGEPVYNAIVWQCRRTAGIVDELKKDDEFAEYVKANTGLLLDAYFSGTKIKWILDNVEGAREKAEKGDLLFGTVDTWLVWKLTNGKVHVTDYTNASRTMLYNIKELRWDEKIINKLGIPTSMLPEVKNSSEVYGHTNLGGVGGVRVPISGMAGDQQCALFGQTCFEKGSAKNTYGTGCFLLMNTGEDMVLSKNGLVTTIAVGINDKIEYALEGSVFVGGAVIQWIRDELQFIHDAADSEYFAKKVEDNGGVYVVPAFVGLGAPYWDMYARGAIFGLTRGANRNHIIRAALESIAYQTNDLLTAMAEDAGCKLASLRVDGGASRNDLLMQFQADISNTQVLRPIITETTALGAAYLAGLAVGFWESKEEIATKWAVSKSYGPTFESAKREKLNKGWKNAVSRVKGWAE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y942_SINMW
Sequence: MKIKWLGHSAFHVETAKAKILIDPFFTGNPAFRDGERRAVTAGLTHILLTHGHGDHVGDTVAIAKETGATVLANFDLCMWLGRQGVAKLEPGNTGGTIRLGSFSATFVNALHSSAQITEDGVSHSLGNANGLVLHFDDEPTLYHMGDTDIFSDMALVQELHEPEIGIVPIGDRFTMGGAVAALACQRYFKFATAIPCHYGSFPIIDQTPETFVAGMDGASTLVATPEVGGIVNA
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Smed_0942.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: HIS6_DECAR
Sequence: MLAKRIIPCLDVTAGRVVKGTNFVGLRDAGDPIEIARRYNEQGADEVTFLDITASSDQRDIILHIIEACAEQVFIPLTVGGGVRKVEDVRRLLNAGADKVSMNTAAVQNPDLIFDASSKVGSQCIVVAIDAKQVAPGQWHVFTHGGRNDTGMDAIEWAKKIDALGAGEILLTSMDRDGTKNGFDLALTRAVSDAVKIPVIASGGVGNLQHLADGVTEGRADAVLAASIFHFGEYTVRQAKEYMASRGIEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBRG1_MOUSE
Sequence: MSVLSGLASEPRTPLSSKARMKRLPRKSQNEKYRLKYLRLRRAAKATVFENASICDEIARLEEKFLKAKEERRYLLKKLLQIHALTEGEPQAAAPSHSSSLPLPYGVTSSVGTMQGAGPSTGAEEPFAKKSKKEKKEKGKENSKLEVLKKTSKKKKMEGGARKLVRPIALDPSGQPVFPIGLGGLTVYSLGEIITNRPGFHDENAIYPVGYCSTRVYASMKCPDQKCLYTCQIKDGGVQPQFEIVPEDDPQNTIVGSSADACYEELLRAISATTGKLMPNPLSCGADFFGFSHPTIHNLIQSCPEAQNCVNYQWVKFDACKPRKGQLSQELPENDATMSLEAFQTQTFDDDHDDSILPGSLDLPELQHEAFVSSYQPEFLTHEPLVDTDLQHLKSPSQCSPIQSSD
What is the function of this protein?
Acts as a growth inhibitor.  Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis.  Redistributes CDKN2A into the nucleoplasm.  Involved in maintaining chromosomal stability.
What are the official names of this protein?
Transforming growth factor beta regulator 1, Nuclear interactor of ARF and Mdm2.
What is the protein family that this protein belongs to?
Belongs to the TBRG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIP7_RAT
Sequence: MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEMILKLAANISGDKLVSLGTCFGKFTKTHKFRLHVTALDFLAPYAKYKVWIKPGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADVPLGFGVAAKSTQDCRKVDPMAIVVFHQADIGEYIRHEETLT
What is the function of this protein?
Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
What are the official names of this protein?
60S ribosome subunit biogenesis protein NIP7 homolog, Nucleolar pre-rRNA processing protein NIP7, PEachy, kDa93.
What is the protein family that this protein belongs to?
Belongs to the NIP7 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CCME_RICB8
Sequence: MQKGAKNRLITIIICFCSAVIGVSIILYNLEKSIVFFVPPSKINEVEQGKELRVGGLVKVDSINKIAADKISFVITDNIKDLEIFYQGVLPALFRENQGIIAIGRLSNGKFIARELLAKHDENYRPPNTVIPAKAGI
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RL16_XANP2
Sequence: MLQPKRTKFRKQFKGRIHGVAKGGTELNFGEFGLKAVEPERVTARQIEAARRALTRHMKRAGRVWIRVFPDVPVSAKPTEVRMGKGKGAPEYWAARIKPGRIMFEIDGVSVETAREALTLAAAKLPIKTRFIQRIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ACTB_MESAU
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells.  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.  Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: ZACN_CANLF
Sequence: MAPRLLLLLLAFLRLGTTGPLVQGRGFRSPTVAWPSFFNFNQPQGVQETIQIPNNGSAPLLVDVQVFVSNVFNVDILRYTVSSMLLLRLSWVDTRLAWNASLYPQHAVTLPWDSLWTPGLTIQEALWVDWQDQSPRARVGPDGHVDLYLALTTETNCDFELLHFPRDQSDCNLSFYALSNTVLELEFRAHAVNEIVSVKREYVVWGLETQIPPRQLVPCFQVTLRLQNTALKAIIALLVPGEALLLADMCGGLLPLRATERIAYKVTLLLGYLVFHSSLVQALPSSSSCNPLLIYYFTVLLLLLFISTMETVLLAALQARGHLSARSSPIPTPRGEQQDHGDLGPHPEEAPGVKESRSWAEAADHIFFLVYVVGVVCSQFFFIGFWMWATCKSDPAPGEAIPHGGQPRL
What is the function of this protein?
Zinc-activated ligand-gated ion channel.
What are the official names of this protein?
Zinc-activated ligand-gated ion channel, Ligand-gated ion channel zinc-activated 1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GERAA_BACSU
Sequence: MEQTEFKEYIHDNLALVLPKLKENDDLVKNKKMLANGLVFYYLYFSEMTDENKVSEAIKTLIKDEETLTLDQVKKRLDQLDARPVETAKKTIESILNGNCAVFINGLDKAYILTTGKKKTRSLTEPTTEKVVRGPKVAFVEDIDTNLALIRQRTSHPKLITKKIMIGENKLKPAAIMYIEGKAKKSVIKEVKARLKNIQLEDIQDSGTLEELIEDNKYSPFPQIQNTERPDKVSSALFNGRVAILVDSSPFVLLVPVSLGILMQSPDDYYERWISASLIRSLRFASIFITLFLSSIYITLVSFHQGLLPTALAVTISANRENVPFPPIFEALLMEVTIELLREAGLRLPNPLGQTIGLVGGVVIGQAAVEANLVSSILVIVVSVIALASFTVPQYGMGLSFRVLRFISMFSAAILGLYGIILFMLVVYTHLTRQTSFGSPYFSPNGFFSLKNTDDSIIRLPIKNKPKEVNNPNEPKTDSTET
What is the function of this protein?
Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine.  Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence.
What are the official names of this protein?
Spore germination protein A1.
What is the protein family that this protein belongs to?
Belongs to the GerABKA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URE2_CUPNH
Sequence: MIPGELMPADGEIELNAGRATVSVTVANTGDRPIQVGSHFHFYETNAALAFDRETARGFRLNIAAGTAVRFEPGQTRTVELVALDGDRIVYGFNGKIMGAL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2218_STRAW
Sequence: MVEEGTMERLRTLGTLGTGIGWRPEIADAVERMPGIDWVEAVAENVCPGHLPESLLRLRARGVTVVPHGVSLGLGGADRPDEGRLAALAERAEALGSPLVTEHIAFVRAGGALTASPLLEAGHLLPVPRTRDALDVLCENVRIAQAALPVPLAVENIAALISWPGEEMTEGQFLYDLVERTGVRLLIDVANLHTNHVNRGEDPAKALDELPVEAIAYVHVAGGFERDGVWHDSHAHPVPQPVLDILADLASRTTPPGVLLERDENFPEPGELERELGAIRKTLEKAGTRAGASAGAAGAATRTAAELTVAESTAVGAIAGPRRGGADAQAAPRAAGTEALSAASTSTPADPARQRLALAQAALLSALVAGTPVPEGFDRVRLGVQARALAAKRADVVAKVAPELPEILAEEYRPAFLTYAPGHPMTGGYRRDALDFAEHLLLAGRPEDAEARRRLRDWWLERSGPTPPSRHPAARLARATRRVLLRR
What are the official names of this protein?
UPF0276 protein SAV_2218.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the UPF0276 family.
Protein: YCX5_YEAST
Sequence: MLFLYTYVYVFLCTNNDVYNETSVMLSKTSAHCFIAEEVTTDNGLICGLAMLGKTKYQFYELFTVYSIQSLTQLASRVKKGGLIMARLILFTLCALPVLFHFILFMLQYLVFVYIEK
What are the official names of this protein?
Uncharacterized protein YCR085W.
Protein: GATA_PROMT
Sequence: MTFEDLRQKLKSGEVSSKELVQEKINRINELDPTLNSFLIVNTELALSKAEHIDKQIASGDHLPPLSGIPIAIKDNLCTKGIKTTCASKILDNFVPPYESTVTKKLLNAGAIMIGKTNMDEFAMGSSTETSAFGPTLNPWNITKVPGGSSGGSAASVAAGLCYGSLGSDTGGSIRQPASFCGVVGMKPTYGRVSRWGLIAFASSLDQVGPFANNVSDAAEILQVISGKDELDSTTVDIPVPNYLETLSKSIKGMKIGLIDNCFDHEGLATDVKESVLSSASLLENLGAEIVNISCPRFNDGIATYYVIAPSEASANLARYDGVKYGFRAEDEQSLIEMTSKSRALGFGSEVKRRILIGTYALSAGYVDAYYKKAQQVRTLIRRDFDDAFKKVDVLLAPTAPTTAFGSGDNIDNPMAMYLSDLLTIPANLAGLPAISLPCGFDKYGLPIGLQLIGNVFEEGKLFQVANQFEKAAEVYKNRPKTDFTL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: OLEC_XANCP
Sequence: MGDNGRMTTLCNIAASLPRLARERPDQIAIRCPGGRGANGMAAYDVTLSYAELDARSDAIAAGLALHGIGRGVRAVVMVRPSPEFFLLMFALFKAGAVPVLVDPGIDKRALKQCLDEAQPQAFIGIPLAQLARRLLRWAPSATQIVTVGGRYCWGGVTLARVERDGAGAGSQLADTAADDVAAILFTSGSTGVPKGVVYRHRHFVGQIELLRNAFDMQPGGVDLPTFPPFALFDPALGLTSVIPDMDPTRPATADPRKLHDAMTRFGVTQLFGSPALMRVLADYGQPLPNVRLATSAGAPVPPDVVAKIRALLPADAQFWTPYGATECLPVAAIEGRTLDATRTATEAGAGTCVGQVVAPNEVRIIAIDDAAIPEWSGVRVLAAGEVGEITVAGPTTTDTYFNRDAATRNAKIRERCSDGSERVVHRMGDVGYFDAEGRLWFCGRKTHRVETATGPLYTEQVEPIFNVHPQVRRTALVGVGTPGQQQPVLCVELQPGVAASAFAEVETALRAVGAAHPHTAGIARFLRHSGFPVDIRHNAKIGREKLAIWAAQQRV
What is the function of this protein?
Involved in olefin biosynthesis (PubMed:21266575, PubMed:28029240, PubMed:28223313).  Catalyzes the conversion of 2-alkyl-3-hydroxyalkanoic acids to beta-lactones in the presence of ATP (PubMed:28029240).
What are the official names of this protein?
Olefin beta-lactone synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S35D3_MOUSE
Sequence: MRQLCRGRVLGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLSLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVSIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFLETRRQSNYEDLESQAEGEERQPSGDQLPFVMEELPAKSGNSEPESAEGAGDSVQQGGQESRGSIRGISLAARSSRAEGHSDEVGRRSLKDTYLEVWRLVRGTKYMKKDYLMENEALPSP
What is the function of this protein?
May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules.
What are the official names of this protein?
Solute carrier family 35 member D3, Fringe connection-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MURD_PARDP
Sequence: MIPVQGVQNQTIAVLGLGRSGRATAAALAAGGARVVAWDDGVDTREQAEQEGLHLLDLTQDQNWDGISALIASPGIPHLYPKPHPVIARAYALGVPVDNDIGLFFRSFATAEWERFDTTPRVIAVTGSNGKSTTTALIHHILKETGRPTQIGGNIGTGVLSLDPAHDGEVVVLELSSYQTDLARALTPDVAVFTNLSPDHLDRHGGLGGYFAAKRRLFAEGGPDRAVIGVDEVEGRYLAGQLGMGAADDRVIRVSSGQKLEGFGWSVFARKGYLAEYRKGRQVASIDLRGIQGLPGAHNHQNACAAYAAARAVGIAPREIERAFHSFQGLPHRSQTVAEIGGVAWVNDSKATNVDAAAKALAAFPRIRWIAGGMGKDGGIEALAPCLGPVVKAYLIGHSARDFALQIGQTPYEIVETMEQAVARAAAEAQPGETVLLAPAAASFDQYPNFEKRGEHFTALVKALQA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_ECOHS
Sequence: MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: EGR1_COTJA
Sequence: CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKVEKAASVSTTSSPVAAYSSSVATSYSSSIATTYPSPVRTVYSSPASSSYPSPAHTAFPSPSIATTYPSGTATFQTQVATSFPSPAVTNNFSSQVTSALSDMTSTFSPRTIEIC
What is the function of this protein?
Transcriptional regulator.  Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity).  Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity).  Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia.  Plays a role in the regulation of cell survival, proliferation and cell death.  Mediates responses to ischemia and hypoxia; regulates the expression of proteins that are involved in inflammatory processes (By similarity).  Plays a role in regulating the expression of circadian clock genes (By similarity).
What are the official names of this protein?
Early growth response protein 1, EGR-1, Zinc finger protein ZENK.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GSA_NOSS1
Sequence: MVNTTIKTTKSQEIFAAAQNLMPGGVSSPVRAFKSVGGQPIVFDHVKGAYIWDVDGNQYIDYVGTWGPAICGHAHPDVIGALHDALEKGTSFGAPSFLENVLAEMVIAAVPSIEMVRFVNSGTEACMAVLRLMRAFTNREKVIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPKSATSSTLTAPYNDLEAVKALFEENRDQIAGVILEPVVGNAGFITPDAGFLEGLRELTHEHGALLVFDEVMTGFRIAYGGAQEKFGVTPDLTTLGKVIGGGLPVGAYGGRRDIMSMIAPAGPVYQAGTLSGNPLAMTAGIKTLELLQKPGAYEYLERITKKLADGLLQVALETGHAACGGHISAMFGLFFTSGPVHNYEDAKNSDTAKFGRFHRGMLERGVYLAPSQFEAGFTSLAHTDEDIDQTIAIAREVLSSI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_STRP4
Sequence: MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CA074_SALSA
Sequence: MASSDVFVAAARKCLRVGKKRFSATVSLNLATQVLAVDLGLKPALLYDSNTASAEQVQQYLNSLQAAQLVSKSLQTLVISENSLIVNPSLTIANLEALLLRRTVTVVDVCHSLEQPAITELQWGAIRDMIQALLAHIRQFGQHSAMRNVPHRIEKRHCETWNLCTLFGILLGYPSTYWFDQSRSFENCLAMSPLVVTKAVASWQGGDSGVEGHRCCLYSFSTPEMLQADTQSVMASWTTQLQERFQQQKVLSGLSVTRSTVTLPSVAL
What are the official names of this protein?
UPF0739 protein C1orf74 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0739 family.
Protein: VE6_HPV13
Sequence: MESANASTPAKTIDQLCKECNLSMHSLQILCVFCRKTLSTAEVYAFQYKSLYIVWRGQFPFAACACCLEIQGKINQFRHFDFAGFAVTVEEDTKQSILDVLIRCYLCHKPLCEVEKLRHILQKARFIKLNSSWKGRCFHCWSSCMENILP
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Sequesters tumor suppressor TP53 in the host cytoplasm and modulates its activity by interacting with host EP300 that results in the reduction of TP53 acetylation and activation.  In turn, apoptosis induced by DNA damage is inhibited.  E6 protects also host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RLMKL_MAGMM
Sequence: MYRYFATTARGLEPALAAELKRMGAKSVRPASAGVGFEGDLEIGLRACLWSRVATRIILSLKKIDVSTPEALYASVLEIPWEDHLDAEGTLSVDCIGTNDTIRHTNFGGQKLKDAVVDRIRDKKGSRPSVARERPDLRINLGIRGNEGRVGIDLSGEGLHRRGYRLRTGDAPLKENLAAALLYFAGWEEQARLGAPFVDPMCGSGTLPIEAAMMAGDIAPGSLRRYFGFRRWRGASGIAELWQRLADESIERQNQAKMPIIEAGDSDANMVHIAQANIEEAELEGHIRLHQRDVAAWQKGADWPDRPGVLVTNPPYGERLGEVVELKGLFAKLGMLLNGPLLGWRSGVLMGDVLWQSAMGLPQQGQRMDLNNGPIPCAYILHGTEPKPQAAKGAPAPKPGLQQGVVSPENAQMFANRLKKNQKRLKKWVTRENVRCYRLYDADMPEYALAVDRYEEWVVVQEYQAPSSIPDADAHRRLQDACSVLPEVLGVPPERVVVKQRKRQKGYNQYDKMANRGQKVLVAEQGLNFEVNLTDYLDTGLFPDHAPMRRRIQQEAANRRFLNLFCYTGTATVHAAAGGALTTTSVDLSNTYLEWAQRNMELNGFKGEHQHRFIKANCMQWIATTDQTFDLIFLDPPTFSNSKSMLESFDIQRDQVTLIGGVARLLNPDGVLYFSTNRKKFKLEQDLLSAQNLHMEEITQQTLDPDFHREPPIHRCWRITCA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_YERPS
Sequence: MRNPAKQEDLIKAFKALLKEEKFSSQGEIVLALQEEGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDVDYNDSVVVINTSPGAAQLIARLLDSLGKAEGILGSIAGDDTIFTTPARGFTVKQLHEAILRLFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_CROS8
Sequence: MMSKQDAAKAPVNPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQQAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPDLEEGDYYWKDLIGCQVVTTEGYSLGKVIDMMETGSNDVLVVKANLKDAFGIKERLLPFLDGQVIKKVDLATQTIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDP3_SCHPO
Sequence: MMVARTRSQKRKLEEINNQKKIKTKKKATGQQTSNTKNLRDVKKKGKQLAYVPRTSPRKSYKNGEYVLAKMSSFPWWPARVASQKSIPTEVRERLKRNFRMDNGIFVQFLPSRDYAIISSSNVLPLTVDESRFILDHDLSTKYIQKTVGLIIASVKRKVSFSDVEEDEFEPENTRKKLQKPIEKPKKEKIEATPKIDGGKRLKNEKSSAEISQTSKQRPSRRSARVRMATDNAQKSPSPIPSPKKTAKKRVRFAGSLEELPKFSLEYQLAQPISTVDMYAQVHYIRFNTLLYYRYQLQEILLSYNHYPQESDMSHVHQILEMIENFSAINSELLESTKLYSLFTLLVKLSDIPLDEKYDFSSRFSTLLLQFQAFVQPKTMTSNVSTAPIGKNAQVNTEAARPSVITT
What is the function of this protein?
Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 acetylation (H3K14ac), critical for DNA damage checkpoint activation.
What are the official names of this protein?
PWWP domain-containing protein 3.
Protein: T1841_DICDI
Sequence: MTQESSSSNHYVDESSFDNNNNNNNNGGEGSSNEILIRIPFLHDSVPALYAMFALASLFVLLATILSAHLIYKHLKYYTQPDHQRYIVRIVFMIPIYAIYSLLSLLLHNYQVYFALLRDCYEAYVLYMFFALCVSYGGGDKNLVTHFTSHPVMRLPMPLFFKFKPNEAFLQVCRMGMLQYVLVRPAVTLASAIFEIFGLYDEGSYAINRFYFYNAFIINVSVTVALYIVVLFYQAAAEELAPYKPLLKFTSIKIVVFFCFWQSIAISGMTNFGWIPTLDGWNSGEVSTGLQNFLICFEMFGVAILHQYAFPYELYRVRAFSAAPLIHRVEMGTVFKSVINSVSQKDMVKETVKSFKGTKITDGKTGLYSGLKDEVFNEFDIEEIEMGDFTSANDNNNFDDFDFSENNINSNNKDNNSSIYNDGASKKNHIGSAILAGGGGGGKKDNDLITDDDFFSLMNNDYANIDFSNFDQDALEEMNFDDDDDDMAFTARR
What is the function of this protein?
Probable transporter.
What are the official names of this protein?
Transmembrane protein 184 homolog DDB_G0284525.
What is the protein family that this protein belongs to?
Belongs to the TMEM184 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUDI_SALDC
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRIKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: RSMJ_VIBC1
Sequence: MQLQLICEDPSQQSHLDELAARWQLSHTDDSDFALVLTTERLELRKVDEPKLGAIFVDLIGGAVGHRRKFGGGKGQAIAKAAGLNKGATPTVLDGTAGLGRDAFVLASLGCKVQMVERHPVVAALLDDGLARAKHDPEIGTWVSERMSLIHASSHDALEQLAQDKDFLQPDVVYLDPMYPHPENKKKSALVKKEMRVFQSLVGADLDADGLLAPAMALASKRVVVKRPDYADWLDEQKPSMAIETKKNRFDVYVKASMA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.