PharMolix/UniProtQA huggingface dataset:
Protein: DDL_WIGBR
Sequence: MKKTVAVLFGGESKEHEISLQSSISIINAIDKKKYNIILIGVEKNGKIGIRSINNYILFKYNINYIKLAPAVSYLYIIPGKNNYQFYSLKNKKMLKIDVIFSILHGSNGENGAFQGLFNTIYTPFVGSNVLSSSICMDKDISKRILSTFGISVVPSITLYYENYKKKINKIINNIKFPCCIKPSNQGSSFGVNVANDFISLKESIDVAFLYSKKILIEPFIQGREIEVGVLGNRNVISSVCGEIKFKKIFYDYKEKYISKKTKIIIPAKISNEISNKIKKIAKLAFISLECSIMARVDFFLTKNKKIFLNEINTIPGFTKNSIYPKLWSKSGLDFKSLINKLILLTIYKK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_STRP8
Sequence: MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIKGQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIETGISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMTVPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDEIAEIESEFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANELKQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRIQDLDYQLSNDDKIDDQLTVIRRGKKKYAVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_PROM9
Sequence: MQFSTFQKNLDNWQGASLIFGVLEEEIASQLENIKFIVDPKLLLKKVTQKKFKGEKGETLSFEFLDQKLETLIIVGLGKSKYLNKSDIENSIGNLIRKTVDKNEKISILLPWELINSQLEINQLAESARLSAYKDNRFNKKKDEKKVLKEIEFLNFKSFENICFEEAEKICEGVELARRLVAAPPNSLTPQEMSMQASQIAKDHGLEVKILEAKECEDLGMGAYLAVAKGSDLDPKFIHLTLKSEGPIKEKIAIVGKGLTFDSGGYNLKVGASQIEMMKYDMGGSAAVLGAAKALGAIKPKGLEIHFIVAACENMINGSAVHPGDVVKASNGKTIEINNTDAEGRLTLADALTYASDLKPDSIIDLATLTGAIVVALGNDVAGFWSNNDDLANDLKAASAQAGEELWRMPLQKAYKEGLKSHIADMKNTGPRAGGSITAALFLEEFFDTEIKWAHIDIAGTCWTDKNKGINPSGATGFGVKTLVQWIKNK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_METPB
Sequence: MARRPGSSSRGPARPDRLAPQAVTSARRPQTPDKSPKPASPDPSLVLLGEFGRPHGLHGEVRLKSFTGEPLAIAGYGPLHASDGRTLELEDARPAPGGSPDLLIVRVKGVDNRSGAEALNRITLAIARERLGQAEDEDEFFLTDLIGLAVEDPSGTVIGTIVAVPNYGGGDLLEIRPAAGGPTALLPFTKAFVPTLDLAGGKVVADPPEDLFAPPGPKPADDPG
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_AZOBR
Sequence: ILVQTAPAGPIDVLIGRPALQRPDIAPRHHAPPHRAEREAVEADRSRRTAGDGWGFAGLRQLPAHAGGQHQQGREGQEKASGRRHVRCHIPLCALSVHTTMHTHALSGIATDGHRRFRRRHLCRPRAS
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Putative histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: HSLU_PSEA6
Sequence: MSEMTPREIVHELDRHIIGQKNAKRAVSVALRNRWRRMQLSGDLRQEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVETIIRDLADIAVKMAKEQETKKVKYRAEEAAEERILDVLLPPAENQWGEKEQNEDKGTRQTFRKKLREGQLDDKEIEIDVALPQVGVEIMAPPGMEEMTNQLQGMFQNLSGSQKKKKKLKIKEAFKLLIEEEAARLVNQEDLKANAIESLEQNGIVFIDEIDKICKREGSNSGGDVSREGVQRDLLPLVEGSTVSTKHGMVKTDHILFIASGAFQMAKPSDLIPELQGRLPIRVELEALTAGDFIRILTEPNASLTEQYIALLKTEGVDVDFTQDGIERIAQAAWQVNERTENIGARRLHTVMERLMEEISFDASEKSGEQLTVDAKYVNDHLEMLVENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_XANC5
Sequence: MGVIQTLDSLMTNPMPEGRVEDILRPEGENPLLEKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGASRLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALVYGILQLQKKIWRTQTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BON2_ARATH
Sequence: MGSCWSDGSYAGGGMVGVGGGANSSAATPNDAVDYYLKSRGYNGLFSQIELSFSASNLRDRDVISKSDAMVVVYTKGRDGTLAELFRSEVVLNSLNPKWIKNFTIGYQFEIVQTLLFRVYDIDTQFQNSKEELLKLDEQQFLGEATCTLSEVVTKSNRTIALELMRKEGVAAQTQPQHNGKLIVHAEESLASKTNTEIVFRGLNLESKDTFSKSDPFLVISKIVEHGTPIPVSKTEVLKNDPNPLWKPVSLSVQQVGSKDSPLVIECLDFNGNGNHDLIGKVQKSLSDLEKLHLAGQGINLALPTGVGHKHEDRVLKSQLFVDKFTETVQHTFLEYLASGFELNFMVAIDFTASNGNPRLPDSLHYIDPTGRLNAYQRAIVEVGEVLQFYDSDKRFPAWGFGARPIDIPVSHCFNLNGSSTYCEVDGIQGIMNAYNGALFNVSFAGPTLFGPVINAAATIASDSLAQSAKKYYVLLIITDGVITDLQETRDSIVSASDLPLSILIVGVGGADYKEMEVLDGDKGEKLESSSGRIASRDIVQFVALRDIQYGEVSVVEALLAELPTQFLTYMRNRNITPTTTTPSST
What is the function of this protein?
Negative regulator of cell death and defense responses.  May repress a number of R genes and may have effects in promoting growth and development.  May function in membrane trafficking and in fusion of vesicles with plasma membrane (By similarity).
What are the official names of this protein?
Protein BONZAI 2.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PHS_BORPE
Sequence: MSTEFPMRIGAEVALPALQGWNAAAGRDAIEKRYRFDNFNAAFGFMARVAMFAEKMDHHPEWRNVYNRVDVTLTTHDAGGVTELDVRMAQFMDEAAGRLGATGLPARADQPRT
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: LNT_RHIME
Sequence: MERLAGRIILLSGVSRTFVGFLAGLLAVLAQPPFGIFAAAFVSFPVLVWLIDGVAPDPGDGLLRRLMPPAAIGWSFGFGYFLGGLWWLGNALLVEADAFAWALPLTVVGLPAVLGLFYALAVVIARSLWSDGWGRIAALALGFGIAEWLRGFLFTGFPWNAIGYAAMPMPLMMQSASVVNLSTINMLAVFVFAAPALIWTGKGARAGLAIAAALFTAHVAFGFYRLAQPAPAPLQPEMTVRVVQPVIDQAKKLDDRERASIFEDHLSLTAAPVQDGAKRPDIVVWPETSIPFILTDNPDALARIADVLQDGQVLVAGAVRVEDAGAGLPPRYYNSVYVIDDRGQIVGAADKVHLVPFGEYLPFEDLLTSWGLSSVAASMPGGFSAASTRPVLTLPGGRRIYPMICYEAIFADEVDGNARLADALLNITNDAWFGDTPGPRQHFHQAQLRAVEAGTPMIRAANTGISAVVDARGVLVVVLGYNYRGVIDTILPGKLPTLTNIATRSQIFWLTTGILFLVAAISRLGFNIRKN
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase, ACT206, Acid-inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUP50_HUMAN
Sequence: MAKRNAEKELTDRNWDQEDEAEEVGTFSMASEEVLKNRAIKKAKRRNVGFESDTGGAFKGFKGLVVPSGGGRFSGFGSGAGGKPLEGLSNGNNITSAPPFASAKAAADPKVAFGSLAANGPTTLVDKVSNPKTNGDSQQPSSSGLASSKACVGNAYHKQLAALNCSVRDWIVKHVNTNPLCDLTPIFKDYEKYLANIEQQHGNSGRNSESESNKVAAETQSPSLFGSTKLQQESTFLFHGNKTEDTPDKKMEVASEKKTDPSSLGATSASFNFGKKVDSSVLGSLSSVPLTGFSFSPGNSSLFGKDTTQSKPVSSPFPTKPLEGQAEGDSGECKGGDEEENDEPPKVVVTEVKEEDAFYSKKCKLFYKKDNEFKEKGIGTLHLKPTANQKTQLLVRADTNLGNILLNVLIPPNMPCTRTGKNNVLIVCVPNPPIDEKNATMPVTMLIRVKTSEDADELHKILLEKKDA
What is the function of this protein?
Component of the nuclear pore complex that has a direct role in nuclear protein import (PubMed:20016008).  Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling (PubMed:20016008).  Interacts with regulatory proteins of cell cycle progression including CDKN1B (By similarity).  This interaction is required for correct intracellular transport and degradation of CDKN1B (By similarity).
What are the official names of this protein?
Nuclear pore complex protein Nup50, 50 kDa nucleoporin, Nuclear pore-associated protein 60 kDa-like, Nucleoporin Nup50.
Protein: PYRB_BACC0
Sequence: MSHLLTMSELSEVEISEILKDAEDFANGKESKTTEQTFVANLFFENSTRTRFSFEVAEKRLGLDVLNFSADASSVQKGETLYDTIRTLESIGTKAVVIRHEQDRYFDELKDQVNIPILNAGDGCGNHPTQCLLDLLTIKQEFGRFEGLKIAIVGDVRHSRVARSNAEALTKLGATIYFASPEEWKDEDNTFGTYKPLDELVPEVDVMMLLRVQHERHDHYETDIMKEYHEKHGLTVEREKRMKEGSIIMHPAPVNRDVEIASELVECERSRIFKQMENGVYVRMAVLKRALPNVLGGMKHELFV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RPPH_HAMD5
Sequence: MIDNDGYRLNVGIVICNKKGQVLWAKRYGQYSWQFPQGGIHLTESPEEAMYRELFEELGLNKKDVRILTSTHYWLRYKLPKHLVRWNTDPVCIGQKQRWFLLELTCDDSNINVECTKAPEFDGWCWVSFWYPVRQVVSFKRDVYRQVMKEFFSFVSLIQKHLI
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: YQ9H_SCHPO
Sequence: MDSIELIPGLPGPGRRLLQLLKDLPSNPSVIVREIPDAIDAFRESITPATRPSCLGLLDTILSCFELPIPTEPIMKALGKLLEPMSWADLKKFGIESYLVTGLEHPSTDVEIFCLHLIRRANWEKKEIGEPLFEAIMACINSRSIAVSEEATVLLFDMADFPYYFNLIIKRFTFVDYEIMNSTLRVRWLTLFAKLSTKSPEYLEELIKDDKLVINGDNKDILLQINFVDVLGIMLEAPFTYEYISSEKTKYLDTIAQDYKGSADSYTDHIGLKFLPRLCELHPDAINSLDEKHQLFDAVRERMKTNDATSILLYGVFLSNTVVTQALIKKYGIEDEANRYVPRWLTRRFLMDEPGMSSFAHALLQPDHNLWMQLWRILPPNTLSTLVNTASSPIPRSRQLAYQCLLHIAQNSPIQIASEGFAIRHLLEAEGDHETCLLRFQVLKTMMESPHGGPKLPFGRYREDILKRLQQGPIVSGASTLKVAAETA
What are the official names of this protein?
Uncharacterized protein C18.17c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ZIPA_SHESA
Sequence: MEDLQLVLFVLGAIAIVAVLVHGFWSIRRQQPKSLKDSPMGNFYKKQAERGEGAPKRVDADGFDADGIGAVRVRKANEAHTPEAPAFNPYLKQEAKAQPQPVEPVQVEPKPLFKQEPSMAQPDFSLQSPTAKEQHRGPKASRQEPVLPGHSANLAQAHVGQSHAAMVAQKAAEEQRAQVQMPTQTALFDEEEAYEEEQPQVVEQPDDDLGEPRDVLVLHVVAKEGQQLNGAELLPCFLTLNFKYGDMNIFHRHVDNAGNGKVLFSIANMVKPGFFDPDNMEQFSTQGVVFFMTLPCYGDALMNFSIMLNSARQLADDIDAVVLDGQRQPWGEFTKQDYLHRIRANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: RS7_ECOBW
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRWLSLRSFSHQAGASSKQPALGYLN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ATP61_CHLP8
Sequence: MHLSSDEVVLWQSGFLKLNLTIVTTWAVMLLLAGGSWLITRRLSTGITISRWQSVLEIIVTMARRQIGEVGLQKPEKYLPFIATLFLFIATANLCTVIPGYEPPTGSLSTTAALALSVFIAVPLFGIAESGLVGYLKTYAEPTPIMLPFNIVGELTRTMALAVRLFGNMMSGDMILVILLTISPLVFPVLMNILGLLTGMVQAYIFSILATVYIAAATRTREKSTS
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 1, ATP synthase F0 sector subunit a 1, F-ATPase subunit 6 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TEX35_MOUSE
Sequence: MSAKNAELKKTNLKKNYKAVCMEPKLTQIYDFKGFKQEGLLIRKGMTRELKNELREVREQLTEKMEEIKQIKDIMDKDFDKLYEFVEIMKEMQQDMDEKMDVLINNQKNNKLPFQNQAKEQQKFWQLGKMDKSSQAMITEEPDGVPLACDKNVVPPKPTRNPLESLHPCQSCCEKCLLCALKTNRNQGRPSHHAWVPFSPLSSGAAF
What are the official names of this protein?
Testis-expressed protein 35, Testis-specific conserved protein of 24 kDa.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENGB_RHILW
Sequence: MPETEKPLFGHPWIFIRGVPSLNFLPPEGPLEVAFAGRSNVGKSSLINALVGQKGLARTSNTPGRTQELNYFVPDGYSGESGDMPPMAIVDMPGYGYAQAPKEQVDKWTKLVFDYLRGRATLKRVYVLIDSRHGIKKNDDDVLDLLDKAAVSYQIVLTKTDKIKAPAVPKLLAETAEKIRKRPAAYPGVLSTSSEKGDGLDDLRQAIGETVGVARWK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PFKA_LACP3
Sequence: MKRIGILTSGGDAPGMNAAVRAVARKAMHEGLEVYGINYGFAGLVAGDIFKMNESTVGDKIQRGGTMLYSARYPQFAQEEGQLRGVEQLNKFGIEALVVIGGDGSYHGALALTRHGFNTIGLPGTIDNDIPYTDFTIGFDTAVNTVVEAVDRLRDTAASHERTFVIEVMGREAGDIALWSGVAGGAEDVIIPEHDFDVKKIASKLQSSRERGQKHAVILLAEGVMHADQFAKELAAHGDFQLRSTVLGHIVRGGAPSARDRVLASQMGSYAVELLLQGKGALAVGIENNKITAHDVRTLFDAKHHAELSLYTLAEELTF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_LISMO
Sequence: MSEKKNKKERLADEIEQEELNILDEAEEAVEEEATADTLTEEQAKILELENKLDEVENRYLRMQADFENVKKRHIADRDASQKYRSQSLAQDLLPALDSFEKALATTSDQEEVKQILKGMEMVYNQILIAFEKEGIEVIPAVGEQFDPNFHQAVMQDSDENAGSNEITAELQKGYKLKDRVIRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEA_LISIN
Sequence: MTTNMLDLFIEEASEHLQALNDNLLQLEKDPTNGQLVSEIFRSAHTFKGMSATMGFQQVADLTHAMENVLDEVRNNRLAVTEHLVDIIFTCTSHLETMVSDIQHGGQGAADISKTVADLEALLHPEQETDTAVEKTYRIAIQIEEAAILKAVRAVMCLERLAEMGIISETTPDREAIELEEFEHSFEVVLETAQTKEEIEAVILDISEIEKVTVTEEVEEVQIIEPIKKAAKQTTKRLENKTIRVQLEKIEKLMNVFEESVIERARIDEIAEKTNNKELMEHLGRFSSISKEIQNGLLNMRMVPVDSVFNRFPKMVRTLAKELGKKIDLVIEGADTEVDKIVIDEIGDPLVHLIRNSVDHGAETVEVRRKNGKNETATINLKAFHSGNNVVIEIVDDGAGINKRKVLEKAIAKNVVTRAESTKMTDSEIFDLLFDSGFSTADQVSDLSGRGVGLDVVRNTILKIGGKISVESSENAGSTFRIEIPLTLSIIQSMLVATSERRYAVPLANVAEAITINPADIQHVHGKDLINYRETIIEVLDLGECFHETPLTDTDELLLLVVKNAKRTFGLIIKDIIGQREIVLKTLGGFFSESQIAFSGATILGDGRVVLILNLETF
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
What are the official names of this protein?
Chemotaxis protein CheA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKNA_MYCLE
Sequence: MSPRIGVMLSGRYRLHRLIATGGMGQVWEAVDSRLGRRVAVKVLKGEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESHMDGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDATPASDVYSLGVIGYEVVSGKRPFTGDGALTVAMKHIKEPPPPLPADLPPNVRELIEITLVKNPGMRYPSGGLFAEAVAAVRAGHRPPRPNQTPSSGRASPTTIPSSTQARAAVACGTKTPAPRRSRPSTSGNRPPPARNTFSSGQRALLWAAGMLGALAIIIAVLIVINSYAGNEQHQPPTPTVTDTGTPPATKTLSGFPAAYCEYRVNWTNHKEISNSGLPKQAARAQLAGATDISPVAGQT
What is the function of this protein?
Protein kinase that regulates many aspects of mycobacterial physiology.  Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins.
What are the official names of this protein?
Serine/threonine-protein kinase PknA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RISB_SHIDS
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: Y1240_LEPBJ
Sequence: MKFTVRVKPNSKKIFFRKEEDGSVTIAVREPALEGKANEAVIETISREMKIPKRKIRIVSGEKGKKKTIEIDP
What are the official names of this protein?
UPF0235 protein LBJ_1240.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: Y1721_HAEIN
Sequence: MTFKLRETIKINHKKVQRIMQWLGLKGKCKTQKYRSYQGEVGHIADNLLQRDFTATQPNEKWTTDITEFKCAEGKLYLSPIKDLFNNEIIAYDLARSPNFEQITRMMKQAVARLEGAKPILHSDQGWQYQMIGYQNILRENGIQQSMSRKGNCLYNSAMESFFGRLKTECYYGKRFETFEQLEKTIHEYIHYYNHERIQGKLKGLSPVNYRTQSLN
What are the official names of this protein?
Uncharacterized transposase-like protein HI_1721.
What is the protein family that this protein belongs to?
Belongs to the transposase IS3/IS150/IS904 family.
Protein: UPP_STRPM
Sequence: MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEVSRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCLVAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CAPON_HUMAN
Sequence: MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV
What is the function of this protein?
Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1.  The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level.  Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1.  Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity).  In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation (PubMed:33523862).
What are the official names of this protein?
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, C-terminal PDZ ligand of neuronal nitric oxide synthase protein, Nitric oxide synthase 1 adaptor protein.
Protein: YOR3_YEREN
Sequence: MYSDPYFAKPAPKSTGREYFNAGWLDKQLNKIPGIKPEDVQATLAELTALSVAEQVQLAGGCERLLVCGGGARNPLVMSRMSTLLPGTEVCVTDDFGVSGDDMEALHSPGWLFEPCPVNRVIYPQ
What are the official names of this protein?
Uncharacterized anhydro-N-acetylmuramic acid kinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: TTCA_ACIBY
Sequence: MYAPVESNEGFNFKPELPTSSAYYRLLKKLRRQVGHAIRDFNMIEDGDKVMVCVSGGKDSYTLLDILLQFKRIAPINFDIVAVNLDQKQPGFPEDVLPRYMEENNIPYYILEKDTYSITKRLTPEGKTYCAVCSRLRRGSLYGFAQEIGATKVALGHHRDDIIATFFLNLFHGGSLKAMPPKLLSSDKKNILIRPLAYVEEKDIIKYAELRKFPIIPCNLCGSQENLQRAMINEMLREWDKQYPKRLHSIFGALQNVSPSQLADRDLFDFEVLDSQRELDFKDPEELKKRLDVVNLSFAAE
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.