PharMolix/UniProtQA huggingface dataset:
Protein: QUEC_BORBR
Sequence: MFRCLMQNHQRRALVLFSGGQDSTTCLAWALERYAHVETLGFDYGQRHRVELDARQVVLRELRANFPDWAQRLGDDHLLDLGILAQVGDTAMTSDREIEMQANGLPNTFVPGRNLLFLTLAAALGYRRQLDVLVGGMCETDFSGYPDCRDDTIKSQQVTLGLGLGTRVTIETPLMWLDKAQTWELADRLGGQALVDMVIEHSHTCYLGERGQRHDWGYGCGHCPACALRKNGWERWVAGAAHAD
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ASSY_YERPY
Sequence: MTTILKHLPINQRVGIAFSGGLDTSAALLWMQKKGAIPYAYTANLGQPDEEDYEAIPRKAMEYGAEKARLIDCRKQLVAEGIAAIQCGAFHNTTAGVTYFNTTPLGRAVTGTMLVAAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNAELKIYKPWLDTDFIDELGGRHEMSEFMIQSGFDYKMSTEKAYSTDSNMLGATHEAKDLEFLNSSVKIVNPIMGVKFWDENVVVKAEEVTVRFERGYPVALNGVVFDDSVELMMEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHANGRVLGRLLYQGRWFDPQALMLRDSIQRWVASEITGEVTLELRRGNDYSILNTVSDNLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFNYVETGLLTSSAATGLPQVDNNNLSSGRGLQDKRQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBIB_MYCTO
Sequence: MTGPEHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLRDGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDRTLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLGVTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTEVAVADEIAAAADLVKGKLTATPVAVVRGFGVSDDGSTARQLLRPGANDLFWLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHHTRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQILYDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAVRGLGSCWIGSTIFAADLVRDELDLPVDWEPLGAIAIGYADEPSGLRDPVPAADLLILK
What is the function of this protein?
Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
What are the official names of this protein?
Bifunctional F420 biosynthesis protein FbiB.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the CofE family.
Protein: P5CR3_MACFA
Sequence: MAAAGSATRRVGFVGAGRMAGAIAQGLIRAGKVEAQRIVASAPTDRNLCHFQALGCQTTHSNQEVLQSCLLVIFATKPHILPAVVAEVAPVVTAEHILVSVAAGVSLSTLEELLPPNTRVLRVLPNLPCVVQEGAIVMARGRHVGSSETKLLQHLLEACGRCEEVPEAYVDIHTGLSGSGVAFVCAFSEALAEGAIKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYGLHALEQGGLRAATMSAVEAATCRARELSRK
What is the function of this protein?
Enzyme that catalyzes the last step in proline biosynthesis.  Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs).  PYCRL is exclusively linked to the conversion of ornithine to proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase 3, P5C reductase 3, P5CR 3, Pyrroline-5-carboxylate reductase-like protein.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_ACTPJ
Sequence: MLILTRKIGESLLIGDNVEITVLSVRGNQVKLGVNAPKEVSVHREEIYQRIKALADDVASDTQQ
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_GEOKA
Sequence: MAKRDYYEILGVSKNATKDEIKKAYRKLSKQYHPDVNKAPDAAEKFKEIKEAYEVLSDDEKRARYDRFGHADPNETFGGGGFQGGGFDFGGFSGFGGFEDIFETFFGAGPRRRASGPRKGADVEYMMTLTFEEAAFGKETEIEIPREETCDTCQGSGAKPGTSPTSCPHCHGSGQVTSEQATPFGRIVNRRTCPVCGGTGRYIPEKCPTCGGTGRVKRRKKIHVKIPAGVDDGQQLRVAGQGEPGVNGGPPGDLYIIFRVEPHEFFKRDGDDIYCEVPLSFAQAALGDEIEVPTLHGHVKLKIPAGTQTGTRFRLKGKGVPNVRGYGQGDQHVIVRVVTPTKLTEKQKQLLREFERLGGDTMHDGPHGRFFEKVKKAFKGEA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN1_STRHA
Sequence: MSRKLRTLMAALCALPLAFAAAPPAHAADPTTMTNGFYADPDSSASRWAAANPGDGRAAAINASIANTPMARWFGSWSGAIGTAAGAYAGAADGRDKLPILVAYNIYNRDYCGGHSAGGAASPSAYADWIARFAGGIAARPAVVILEPDSLGDYGCMNPAQIDEREAMLTNALVQFNRQAPNTWVYMDAGNPRWADAATMARRLHEAGLRQAHGFSLNVSNYITTAENTAYGNAVNNELAARYGYTKPFVVDTSRNGNGSNGEWCNPSGRRIGTPTRTGGGAEMLLWIKTPGESDGNCGVGSGSTAGQFLPEVAYKMIYGY
What is the function of this protein?
Implicated in the mechanism of induction exerted by cellobiose.
What are the official names of this protein?
Endoglucanase 1, CEL1, CMCase I, Cellulase I, Endo-1,4-beta-glucanase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 6 (cellulase B) family.
Protein: RS4_MYCLE
Sequence: MARYTGPITRKSRRLRIDLVGGDQAFEKRPYPPGQHGRARIKESEYLLQLQEKQKARFTYGVMEKQFRRYYEEAVRQPGKTGEELLKILESRLDNVIYRAGLARTRRMARQLVSHGHFSVNGVHVNVPSYRVSQYDIIDIRDKSLDTVPFQIARETVGDRPIPSWLQVVGEHQRILIHQLPERVQIEVPLIEQLIVEYYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: EXPI_PECPM
Sequence: MLEIFDVSYTLLSEKKSEELFTLRKETFKDRLNWAVKCINGMEFDQYDDDNATYLFGVEGDQVICSSRLIETKYPNMITGTFFPYFEKIDIPEGKYIESSRFFVDKARSKTILGNSYPVSTMFFLATVNYSKSKGYDGVYTIVSHPMLTILKRSGWKISIVEQGMSEKHERVYLLFLPVDNESQDVLVRRINHNQEFVESKLREWPLSFEPMTEPVG
What is the function of this protein?
Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), an autoinducer molecule which binds to ExpR and thus acts in virulence (soft rot disease) through the activation of genes for plant tissue macerating enzymes.
What are the official names of this protein?
Acyl-homoserine-lactone synthase, Autoinducer synthesis protein ExpI.
What is the protein family that this protein belongs to?
Belongs to the autoinducer synthase family.
Protein: PUR9_BACMK
Sequence: MKKRALVSVSDKTGVVEFVKGLLEQGIEVISTGGTKKLLEENGLQVIGISEVTGFPEIMDGRVKTLHPNIHGGLLAVRDNEMHVAQMNELGIQPIDFVVVNLYPFKETIAKPDVTFADAIENIDIGGPTMIRSAAKNHKFVSVIVDPVDYDVVLAELKENGEVTEETKRKLAAKVFRHTAAYDALISNYLTKQMGEESPETVTVTFEKKQDLRYGENPHQKATFYKAPFAATSSVAYAEQLHGKELSYNNINDADAALSIVKEFTEPAVVAVKHMNPCGVGVGADIHEAYTRAYEADPVSIFGGIIAANREIDKATAEKLHEIFLEIVIAPSFSQEALEVLQSKKNLRLLTVNIEKATSASKKLTSVQGGLLVQEEDTLSLDEDAISIPTKREPSEQEWKDLKLAWKVVKHVKSNAIVLANDNMTVGVGAGQMNRVGSAKIAITQAGEKAQGSALASDAFFPMPDTVEEAAKAGITAIIQPGGSIRDEDSIKMADAYGITMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CYB6_SYNE7
Sequence: MSKVYDWFEERLEIQAIAEDVSSKYVPPHVNIFYCLGGITLTCFLIQFATGFAMTFYYKPTVAEAYSSVQFIMNQVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKRPRELTWVTGVVMAVITVTFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGSAMVELLRGGQSVGQATLTRFYSLHTFVLPWLIAVFMLLHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RPOB_MESVI
Sequence: MMIIEEYTPVPNTAFDFKIPDLIEMQLSSFRIFLKKGLIEELKDFSVISNSKKNLELRFFPEKYKLKRPKYNERTSIRRASTYTCQLYVPAKLTNKRTGEIQEQDVFLGEIPLMTGRGSFIINGSSRVIVNQIVRSPGIYYKREIDKKGRKTHSATIISNRGAWLRIETDKNGLIWARIGKIRKVSIMIVFKAMGLTKNEIFDALKYPQFLKKTIQETDPYLENDIQHDDDFENESTSTLLSTREILESRFFQSKYYDLGKVGRYKINKKLQLNIPENIRVLTVQDILAAVDYLINLEFNIGTLDDIDHLKNRRVRSVGELIQNQVRVGLGRLERMIYKRMGESSPDSLTLTSLVNPKPLVGAIREFFGSSQLSQFMDQTNPLSEITHKRRLSCLGPGGLSRERAGLAVRDIHPSHYGRICPIETPEGPNAGLIGSLATHSRVNEYGFLESPFYITKNRKVIKSELPIYLAPDQEDQFKVAPGDLLLSCYSSIENNYVPVRYKQEFTTSKAEEVDYVGISPTQAISIATSLIPFLEHDDANRALMGSNMQRQAVPLLKPNRPIVGTGFEEQVALDSGTVVICRHKGIVISVDSKTILVRSLRMNAKGIQHSHIDRYYLQKYNRSNQDTCINQKPVVSQGEWVQKGDILADGSATVNGELTLGQNILVAYMPWEGYNFEDAILISEKLVYEDIYTSIHIEKYEVDARKTKLGPEKITREIPNVNDHLLRNLDDNGIVIPGARVESGDILVGKVTPKEDLDQHPEGKLLRAIFGEKARDVRDSSLRVPNGVSGTVVNVRRLTGKELPSGVIMMVHVSISQKRKIQVGDKMAGRHGNKGIISKILPRQDMPYLQDGTPVDMVLNPLGVPSRMNVGQVFECLLGLAGEYLSENYKLMPFDEMYGKETSRGLVYSKLYEARQKTGYPWLFNIQSPGKSKLFDGRTGESFDQPVTIGKAYMLKLVHLVDDKIHARSTGPYSLVTQQPLGGRAKHGGQRLGEMEVWALEGFGAAYTLQELLTIKSDDMKGRNDALNAIIKGRPIPKPGTPESFKVLIRELQSLCLDIGVYKVHKSNKNQEIDLMQNF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TTCA_COXB2
Sequence: MSEKRVEKKLIHYVKKALNDYRMINTGDRVMVCLSGGKDSYTLLSLLNSIRIEGNYKFDIFAFVLDQSQPGWDDSALRGWLDDKKISYEILTRDTYSIVKEKIPAGKTYCSLCSRLRRGIIYRYAEEQGFSKIALGHHRDDLIQTLLMSVFYNGQIRSMPPKLLSDNKRHVLIRPLAYCQERDIIKYAMEQQFPLIPCNLCGSQKNLMRQRVKRLISDLAKENPKVPSNILRALSNIKPSQLMDHELWNFRELNVD
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNRE_DROGR
Sequence: MVKYLNQKEAINVDLELFNEYKFSVDQLMELAGLSCAHAITKCFPADRFGRVLVCCGPGNNGGDGLVCARHLALMGYTPAIYYPKPTAKPLFENLSHQCQRMEICRIDECPTVETSANSYDLIVDALFGFSFKPPVRVDFVPVVELLQQTKLPIASVDIPSGWDVENGKLNDCDLEPTLLISLTAPKLCAKHFKGKHHFLGGRFVPPALQRKYELNLPEYPGNELCLELETHK
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: SSN8_EMENI
Sequence: MAANYWASTQRKHWLFTRERLAEIRESFKEKDKASHTHFPLPDQRLLNIYFNQQLIKLGKRMSTRQQALATAQVYIKRYYTKNEIRNTNPYLVLTTAFYLACKMEECPQHIRFVVSEARALWPEFIVPDVSKVGECEFSLISEMQAQLIVHHPYRTLSELQPELSLTSDEVALAWSVINDHYLTDLSLLYPPHIIAVMAIIVAVVFKPSSQTAFHGSAAPIAGAMRDGGMNILAALSDKGGAGPPPRIQKLIAWLAESEVDIKAVIESTQELVSLYEVWEQYSEKNCKELLGRMIRSKSLDK
What is the function of this protein?
Component of the srb8-11 complex.  The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
RNA polymerase II holoenzyme cyclin-like subunit.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: EAF_DROPS
Sequence: MMMTKQKNTLAERLNIGDEVRELKLGSTFNPKNTSTAFHTIKYDFKPASVDTSRMATVDVGSNNQVTVIVPNSELALNVRLLIFGLTESSGVPHTVYKGNQREYAKECLMIYDKETGAITIEKLNHNIQVKKTRTEVTNKPVQLPAQSVPMNMGHQGQVLGTNGSVPPPMAQLAQGPLSGPGGKLENSTMRVSSKTKVSTGSRRNNIIDFKPRNSPMQQSSPSRPVVTHRSPQSAPAWDANNAQQTLPSIPMITDDDDFGLRAALHNGGQANISGSSTGSSSGQPDLYGSSSSSHMGKQRQAHGKRQQIHQRSSPPVQQQPHYQQQQQPNYGRAYNGASNYAQQQQPQPQQQRHSPHQQPHQQQHQRHSPQQQQQRHSPQQLQQQRPTSYGHSNNMPMDLDSSREHDLASQSVAQAAAVLEQQIGGALSASSSSSESDSSDSDSGSDSDDSTEDDRSMKEQQEQQQQQQLQHQQLQLQHQQIQQPAPHHQRHQQQQSQQHMNQLPNLGLGSISPSYNNHHNHQQPQPQPQQQQMSGVYASNGGFPNDLLQNDLQLSSNSSDDDD
What is the function of this protein?
Promotes transcriptional elongation by Su(Tpl)/ELL.  Essential for development (By similarity).
What are the official names of this protein?
Ell-associated factor Eaf.
What is the protein family that this protein belongs to?
Belongs to the EAF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCNAA_TITDI
Sequence: MWTFAIVLAFLLIGLDEGEALDGYPLSKNNYCKIYCPNTEVCKDTCKRRAGATDGECRWDGCYCFNVAPDTKMYPGELPCH
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This toxin binds, in vitro, to sodium channels and inhibits the inactivation of the activated channels.  Seems not toxic to mice, crickets and sweet-water shrimps (By similarity).
What are the official names of this protein?
Toxin TdNa10, T-alpha* NaTx7.2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VERB_PENPO
Sequence: MHPSARLYNNIALWFYDYLVHSIFMVYGWHCPTKSVGLPFFSSHVGPKHMDVGVGTGYFPVAVRKSSRKRNGQLKPQWPQKLMLVDLNPNCTAMAATRVGAPDCTETLTADVLQPIPAAGKHETFDSLSLMNVLHCLPGTSESKAQAFGHLKPFLKEDGVLFGSTILGRGVEHNRFGRLVMWLSNSLGIFHNYGDHPDDFVRALQKDFNQVEHVVVGRVLLFTAKEPN
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of the neurotoxin verrucosidin, a methylated alpha-pyrone polyketide that inhibits oxidative phosphorylation in mitochondria and thereby causes neurological diseases (PubMed:34093475).  The carbon backbone of verrucosidin is synthesized by the HR-PKS verA, and further modified by the other verrucodidin cluster enzymes (Probable).
What are the official names of this protein?
Methyltransferase verB, Cluster 4 protein B, Verrucosidin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: HFQ_ALBFT
Sequence: MSNKGQLLQDPFLNALRREHVPVSIYLVNGIKLQGQIESFDQYVVLLRNTVTQMVYKHAISTIVPGRAVNFSTGEGDEPAAA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: OBG_STACT
Sequence: MFVDQVKILLKAGDGGNGITAYRREKYVPFGGPAGGDGGRGASVIFEVDEGLRTLLDFRYQRQFKAKRGEGGQGSNMHGKNAEDLVLKVPPGTLIKDAETEEVLADLVEAGQRAVVAKGGRGGRGNSRFATPRNPAPDFSENGEPGEEIEVTLELKLLADVGLVGFPSVGKSTLLSVVSKAKPKIGAYHFTTIKPNLGVVSTPDGRSFVLADLPGLIEGASEGVGLGHQFLRHVERTKVIVHVIDMSGSEGRDPLEDYKTINKELESYGQHLEDRPQIVVANKMDLLDAEDNLELFKEEVGDDVEIIPISAYTKENIDQLLYAIADKLDEYKDVDFTKEDDEALGVNRVLYKHTPSQDTFTITRDDDAAYVVSGKAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGAKNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT2A3_RAT
Sequence: MEEAHLLSAADVLRRFSVTAEGGLTLEQVTDARERYGPNELPTEEGKSLWELVVEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTDAIPDPRAVNQDKKNMLFSGTNIASGKALGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAEAGACRLHEFTISGTTYTPEGEVRQGEQLVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRVERAGACNSVIKQLMQKEFTLEFSRDRKSMSVYCTPTRADPKAQGSKMFVKGAPESVIERCSSVRVGSRTVPLSATSREHILAKIRDWGSGSHTLRCLALATRDTPPRKEDMQLDDCSQFVQYETGLTFVGCVGMLDPPRPEVAACITRCSRAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVLGKAYTGREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRNPREALISGWLFFRYLAIGVYVGLATVAAATWWFLYDAEGPQVTFHQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLGAVVMSMALHFLILLVPPLPLIFQVTPLSGRQWGVVLQMSLPVILLDEALKYLSRHHVDEKKDLK
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.  Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen.  Contributes to calcium sequestration involved in muscular excitation/contraction.
What are the official names of this protein?
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, SERCA3, SR Ca(2+)-ATPase 3, Calcium pump 3.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TRMFO_HYPNA
Sequence: MTLKPIHVIGGGMAGSEAAWQIASAGVPVILHEMRGVRGTDAHQTDKLAELVCSNSFRSDDHTTNAVGVIHEEMRRANGLIITTAKDHQVPAGSALAVDREGFSEAITAKLEAHPLVTIVREEIAGLPPEDWDSVIVATGPLTSIALAEAVRAHTGETDLAFFDAIAPIVYFESIDMDKAWRQSRYDKAGPSGDTAAYINCPMTEEQYNAFLDALLAAPKTEFRDWEKDTPYFEGCLPIEVMAERGRETLRFGPMKPVGLTNPHNPTVKAHAIVQLRQDNALGTLWNMVGFQTKLKYAAQTDIFRMIPGLEKAEFARLGGIHRNTFLNSPKLLDRQLRMKSMPRLRFAGQVTGVEGYVESAAMGLLAGRFAAAERLGQRLEPPPPTTAMGALISHITGGHLAEKQTFQPMNVNFGLFPDITDYSKTDENGKRLRGKDKGRAKKIAQAIRALQDFDAWLAGEAVVAAE
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESPG1_MYCTU
Sequence: MTGPSAAGRAGTADNVVGVEVTIDGMLVIADRLHLVDFPVTLGIRPNIPQEDLRDIVWEQVQRDLTAQGVLDLHGEPQPTVAEMVETLGRPDRTLEGRWWRRDIGGVMVRFVVCRRGDRHVIAARDGDMLVLQLVAPQVGLAGMVTAVLGPAEPANVEPLTGVATELAECTTASQLTQYGIAPASARVYAEIVGNPTGWVEIVASQRHPGGTTTQTDAAAGVLDSKLGRLVSLPRRVGGDLYGSFLPGTQQNLERALDGLLELLPAGAWLDHTSDHAQASSRG
What is the function of this protein?
Specific chaperone for cognate PE/PPE proteins.  Plays an important role in preventing aggregation of PE/PPE dimers.
What are the official names of this protein?
ESX-1 secretion-associated protein EspG1.
What is the protein family that this protein belongs to?
Belongs to the EspG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_THEVB
Sequence: MFTLTQLCPTPLENARQLHLSLTAEERCRRRLHCHSDEGESLYLKLPRGITLQPGDRLRDEDATVIVTVHAKPEPTLKVMASTPLDLLRAAYHLGNRHVPLEIHTDYLRLGADSVVQTMLEQRGLTVTFEVAPFCPERGAYHAH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU_FLAJ1
Sequence: MRSIWTGSVSFGLINIPIKMFSAVQESSLDMDMLDKKDNANIKFKRVNENTGKEVDFANIVKGYMLNDKYVILDDSDFEAADAIKTKTIDIESFVLEKEIESIYYEQPYYLEPDKGAMNAYGLLRDALQASGKVGVTRFVLRNKESLAILKPYKNVIVLNRIRFEQEIRSTDELNLPPISKKATKEMDMAEKLIDQLTEKFDITGFKDEYTTKLLDIIKKKAKGKVQKTAPKMKVVHKQGDDLMSMLKASLETKKKKSS
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: PGK2_METTH
Sequence: MIMVQGEVSGKKYTEPFSKGVLARSLTRAEMDPNRAYTFASRIEAHLKKNKVDLITIEELVEIVSEHLRKEDPEVAEKYMLWRKIRQCKEPLIILIGGASGVGTSSIAFEVANRLGIRNMISTDMIREVMRKIVSRELLPSIYESSYTAYQSLRIPPPPELDEVLIGFRDHVESVSIGVEAVIERALTEGISIVIEGVHIVPGFIREDLVNKENVAMFVLTVSDENVHKGRFYSRCRQMWARRPLKRYISYFWAIRRIHRYIENQARKHGVPVIENIDVVTTIDSIIKSLTKTTVKGGEKGAEKTE
What is the function of this protein?
Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3-diphosphoglycerate.  Involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant.
What are the official names of this protein?
2-phosphoglycerate kinase, 2PGK.
What is the protein family that this protein belongs to?
Belongs to the 2-phosphoglycerate kinase family.
Protein: Y889_ALIF1
Sequence: MNIDVATLLSQNDILLLFVVLALGLFIAKLRIGSFQLGSSIGVLITALFMGSLGYTFTADSLNIGFMLFIFCVGIEAGPNFFGIFLRDGKHYLLLVLVVLVSAVSLSFLTGHYFGLDYGLSTGMMAGALTATPVLVGAKDALNSGLAALPEGVDFSKVIDNLSVGYAFSYLIGLTSLILLARLLPKLQKQNLQDSAMQIAQERGIGSAGQRKVYLPIIRAYRVGQELIDWTDGKNLRELGIHRQTGCHIERIRRNGILANPDGDYILQQGDEIALVGYPDSHARLDSSFRNGKEVFDRNLLDLRIAEEEIVVKSDNIAGKRLSELNLSEYGCFLNRVVRAQIEMPIEHDIVLAKGDILQVSGEKSKVHYLADKIGFISIHSQVSDLLAFCSFFILGIMFGMITMSFGQVTFGLGNAVGLLISGITLGFLRANHPTFGYVPQGALNMTKNLGLLVFMVGIGLSAGGNINEYFSEDGLKVLAAAFIVSVIPVILAYLVGAYILNMNRALLIGAIIGARTCGPAMDVVNEHARSTIPALGYAGTYAIANILMTVAGTIMILLA
What are the official names of this protein?
Putative transport protein VF_0889.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.