PharMolix/UniProtQA huggingface dataset:
Protein: MRAY_SALPC
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIARLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLIGYGIIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPVTQLVVPFFKDVMPQLGLFYILLSYFVIVGTGNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_ACISJ
Sequence: MSETRAVLRGVRLSVDKGRLVADLIRGKKVDQALNILAFTQKKAAVIVKKVLESAIANAEHNDGADIDDLKVKTIFVEQGTTLKRFTARAKGRGNRISKPTCHIYVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: EAF11_USTMA
Sequence: MSTEPVSSLALPAPAILPTTPIPASTQQASSLVSDQIQEASTASQKSVTSITQPPIPSQQQPPQHITANHPASIAAAATVALSATLLNPNEWNALASTSMVTLDDLRSAFLEQRQQQLKDLERSHRESLREMIFMSENYDKEDVAGSPWKLGQSLQVAEDDAREHVKSFLDQHRLALDPKMSIKDHILEQPKLLRQRVSQELKTGPIELAPPPTPTSATAPSAGEAQRDRDLKREIEQNNLHRSQAVARAAAAVQAHAIAEGVAKIKPLTITAAESQGVRVAPLQPGQVPSFVIESTTPIAHIVASSDSSTAVLVASDAQKVDSHTTMSAAEAVTPAIKVESTDNIDASPSKASHALEKAVSPVPGLARNASTQSTSLRVPPSPMVVPTIPENITAPPLHPTLQVLAPNPLSVTYAASLRPLPPDPTRRITGAGLSGGAIHHRSGRKITSLSNHSNVNSYSSIAAAKIGPAGSGQADLYRWYVRARASPGAGMVGKADKCLMTSDWRVAFNEQRFVRAMARIEKLKAQGEWSFRQPKKQKGPVVRKAHWDHLLEEMKWLQTDFREERRWKMTVAFHLAHEVAAWHRARTPAERAQFCVHVQRSYRHRTISDNVEQHNTDKLSAKEVVSSSQPFQAAAASLDDVEMTHSTSSSHIQKDGEPATVKAESGQPVEDADVTMDGGADADEAVTQAVESALQTTNEAASARAEEMDADGEDDADTDANDVEAATAALVSGEPSKPPKVEVVREPLSQPQPMPTLADVSVPTTSSATPTVPASSTPTTAANDKLVHALRSQPKDADSTLTAEMPPQLLATLRAPIFSTSVTTTVVSPAALLDSLNPEAAAALLGIEVSDLANAADLLEPGSLSFSKMFPELPLYGGVSLPESNSKSDRRWDEGSLNQPPRLTHVTKLLDSRPLLVSTLEPSKNRANGRWLADSDWVVAAEQSDPLRGVTDGADTALPPMPGSLLFARKSNRAAKDASGPASTTPAEPASPDARAALFVWTPDEDNYLMTLAKQYHNNWALVADLFNSTRLNTATDKREAWDCYDRCKRIEQAAAEGKPPPGPPPMPAPAADADKDSKKGDGKDADASSSKRDKLSKKSGSKHDGSKRKQRRSNLMEVMRRSAKRREATKQAQQTQQTKKVNLNTHETHAQIKAGPAITPQSLSALKTERDQAALRQYYEQQRAQLAYQQQQQQQQRLLAQQAQAQRMAQQQGTAGTSAPAATAVTQAGKAGTAIVAGGTGGVGNVSLLPAGTPAASAGPAGQAQQKAATGQGTNQAIAQQTQQQQQQPQSQQTAQMQVQQPPAAAAAAQQQQQQQVQLQSQLQASQAAQMQNLYAQMQQQQQQQQRQQQQQLGQAAAGLAQVRPGVGALTQQQLATLTPQQQQQYHAQLAAATAAAQQQQLRSQMAAVAAAQGGQAGFQLPNAQAQAQAQAQAQFQLMQQQQQQQNVMQNQGRPAMAQQAQQAALQMYQQQQRQAQMRPPQPTQPFAARPNARPGTAASSQAKPQAAARSATPAPPMPATVQALQQQLAISLATSNLSAEQINGLAIQLYKQAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQQPAPTQQRPPPQQLLNQAIQALAAQTQKNQQPAPTVHGVTGSPVRPPTPRPS
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF1, ESA1-associated factor 1, Vacuolar import and degradation protein 21.
What is the protein family that this protein belongs to?
Belongs to the EAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MYOC_DICDI
Sequence: MAQQKPEWGNQMKNEGLDDMTLLSKVSNDQILDNLKKRFEKDIIYTNIGDVLISVNPFKFIDGMYSDEVLQEYIGKSRIELPPHVFAVAEQTYRSMINEKENQCVIISGESGAGKTEAAKKIMQYIADVSGERGSSSNQKVEHVKSIILETNPLLEAFGNAKTLRNNNSSRFGKYFEIQFNQKNEPEGGKITNYLLEKSRVVFQLKGERNFHIFYQFCRGATPQEQQEFGIYGPENFAYLTKGDTLDIDGVDDVEEFALTRNAMNVIGIPANEQKQIFKLLAAILWIGNIDFKEQAGDKVTIADTSVLDFVSQLLDVPSHFLKTALEFRQMETRHGNQRGTQYNVPLNKTQAIAGRDALAKAIYDRLFNWLVDRINKEMDNPQKGLMIGVLDIYGFEVFDRNGFEQFCINYVNEKLQQIFIEFTLKMEQEEYVREGIKWEPIPFFDNKIVCELIEGKNPPGIFSILDDVCRAVHSQAEGADQKLLQSIAVCKSNPHFDTRGNAFCVKHYAGDVVYEGPGMIEKNKDTLLKDHLEILQMSANNFLVGLFPDVIDTDSKKLPSTAGFKIKSQAAELVATLMKSTPHYIRTIKPNDLKKPNILEGGRVLHQVKYLGLLDNIKVRRAGFAYRATFDRFFQRYYLLSDKTCYAGNNIWKGDALSACRAILASQNVDNTQYQIGKTKIFIRYPEMLFSLEETRERYWHDMASRIKNAYRNYKAFQFECSNRIKNAFRNYKLYRQRCAQTIQGYFRAWKQASPFFDLRMQNEQLFQGRKERNRFSMISVRKYFGDYLDVRSQSYFLDAMAEGRNEDVIFSSKSQVMVHPILSANKLSPRFLIVTKQAIYLIKLKQKKNLATYLLDRRVPLAEVTSFSLSSLADNLLVIHTSTQFDVAVTTEFKTELVALINKQKGTTLAVNFGQSIQYFKKKGSNNTVTFLKDEMHKEIFLKKNQFHIASGLPASTTVAKVRKNPSQVSTPSKPIAKPVAKPMVAKPSGGSVIMKKPAPAAPPSGPPVMKKPAPTAPGGAPMMKKPAPAPGGAPMMKKPAPVPGGPAPGGSAIMKPAGGVSKPLPSPTGAPMMKKPAPTAPGGPAPAGAPTPMMKKPAGQPMMKPIAKPQPTPMKKPAAPPPQQYIALYEYDAMQPDELTFKENDVINLIKKVDADWWQGELVRTKQIGMLPSNYVQQI
What is the function of this protein?
Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.  Involved in the process of phagocytosis and appears to support streaming behavior.
What are the official names of this protein?
Myosin IC heavy chain.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cell projection, lamellipodium. Note=Found in the leading edge of translocating cells.
Protein: UBIC_SHIDS
Sequence: MSHPALTQLRALRYFKEIPALEPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSGPELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2012_BOVIN
Sequence: MFTLSLLSRGHGKLVQNKQKLEVYFEPEDYLNWKSPEDYILVRKPQDEGNADQHTWSLFLPKTFSTRKGALILYSEGLAISAWTPEERRKGPYRPKGRRKRPDLELHTLQDLKEAILAYGRRQREQDRAWQPYLHFRSQPESQGLRQIQPGYSAKRYLRGLLRTWPPGTINKLQCAGYIKDSVLLQDSQLNVPKNLRPQQDLSGVPLKYHLLPVFPPFWIQQGKSFGQGQQDLDEGEAGAGGQVDQGSVVKDRGIQGTCLPPLKKQPWQKDETQTEDTSKDNHHCIHTSKENHQEKAQQTSRRTLGHALFDHSWLLHDKSHTTFYYGGTFPNRKADLSDKQGTMKLHQGRSSHLFKEPPAERCLFPPVASAAGSEKNMPGDMKKKKAPKALKLPLISEEPPRVLDPLRSQLKASEPPAELFIFPVEIHYHSQHPPKGKAQRRGAPQPESAPETEEYTSSWRPPLKQVSLRGSRALRVHLPMDTDRDTLSPQEDVAPPQKGTSSPSLRKGKKSPESQRGPDSPRTSGRSSPTGPPCERPAGGALPAAGQAYESVSSNAGHGEEESSIQHLLKVNTESRTDLHMNLNETSPLTQKPENQGAQQSLEAAAQKTGEPQSCINKGLICSNRKEFYTRKLHLDMTPFLKASREEMDDHEEGGELRENHPDAQDPVRRNMTLDPLCASLAKHMQTPEADTVQKASKDYNVHHRHRGLSGHGPDSPEGLDPIDTSFLPRGKEGKTEPRLFNQKTSNNISNEMELIEKAKSRKRAKTDKSKAPKREKEGKLHEEAEAAVGKSKESKAEKKSQLISKGKKTGAKGKRTRKEGNLETAAELSGPDGINSKETKDRSGGGFFRSGSGVEDPWVSSKVEAPESQVSIDGRSSPTQTAAVPGNMEPEEDRSHEDPSKAFLVKREQEKASRDRLRAERAEMRRLEVERKRREQEEQRRLQQEQLERAERMKEELELEQQRRVEEIRLRKQRLEEERQWQEEEERRQWLQLQMAQERARQQQEEFRRKCQELQRKKQQEEAERAEAEKQRLKELEMQLAEEQKHLMEMAEEERLEYQRRKQEAEEKTRWEAEDRRQKEKEAARLAQEEAMKQAQDQARQKDALKKHLHFHQELHKEASGLQWTHNISRPWVYSYFHFLQIPRP
What are the official names of this protein?
Uncharacterized protein KIAA2012 homolog.
Protein: ISPDF_PARDP
Sequence: MTIPATYAAIITAAGRGTRAGDGPPKQWRPLAGQSVLERSIAAFAGFPRVVVTLAPEDMARGVAELSGPVVLVAGGATRSDSVRAALESLEGSGVTHVLIHDGARPLVSRRVIGGVIEALQSGAPAAAPALPVTDALWRAQDGCVTATASREGLFRAQTPQGFALDAILAAHRAHPEGAADDVELAIRAGLPVTVTPGDEDNLKLTWPGDFARAERILGDAMDIRLGNGFDVHAFTTGDHVWLCGVKIPHDKALLGHSDADVGMHALTDAIYGALAQGDIGRHFPPSDPQWKGAESHIFLRHAAMLARQMGYEISNADVTLICERPKVGPHAGAMALRLSEIIGVEPDRVSVKATTSERLGFTGREEGIASIATATLVKG
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: DUT_HAES1
Sequence: MKKIDVKILDPRIGTEFPLPTYATIGSAGLDLRALVDEGFEVQPGETKLISTGLSIYIADPNLAAVILPRSGLGHKNGIVLGNLVGLIDSDYQGPLMVSLWNRSDKPFKIEIGDRIAQLVFVPVVQAEFNIVEEFQQTDRGNGGFGHSGKK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PYRI_METJA
Sequence: MIPMEELKVKKITNGTVIDHIDAGKALMVFKVLNVPKETSVMIAINVPSKKKGKKDILKIEGIELKKEDVDKISLISPDVTINIIRNGKVVEKLKPQIPDEIEGTLKCTNPNCITNKEKVRGKFKIESKNPLKIRCYYCEKFLNEVIFE
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: PDK1A_XENLA
Sequence: MVSSQPKYDLIREVGRGSYGVVYEALVRRTSQRVAVKKIRCQAPENVELALREFWALSSIQSQHPNVIHMEECVLQKDGMVQRMLHGSSSVLYLPLVETSLKGEIAFDPRSIYCLWFVMDFCDGGDMNEYILTRRPSRRTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILVCKSRDGVDEPTLKVADFGLSKVCSSSGLNPEEPANVNKSFLSTACGTDFYMAPEVWEGHYTAKADIFALGVILWAMLERITITDTHTKKRLLGGYVQRGAQVVPVGEALLENPKLELLIPVKKKSMNRRMKQLLHQMLSANPQERPDAFQLELKLIQIAFRDYTWET
What are the official names of this protein?
Serine/threonine-protein kinase pdik1l-A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEPA_STRPM
Sequence: MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RDRP_TRVPP
Sequence: MANGNFKLSQLLNVDEMSAEQRSHFFDLMLTKPDCEIGQMMQRVVVDKVDDMIRERKTKDPVIVHEVLSQKEQNKLMEIYPEFNIVFKDDKNMVHGFAAAERKLQALLLLDRVPALQEVDDIGGQWSFWVTRGEKRIHSCCPNLDIRDDQREISRQIFLTAIGDQARSGKRQMSENELWMYDQFRKNIAAPNAVRCNNTYHGCTCRGFSDGKKKGAQYAIALHSLYDFKLKDLMATMVEKKTKVGHAAMLFAPESMLVDEGPLPSVDGYYMKKNGKIYFGFEKDPSFSYIHDWEEYKKYLLGKPVSYQGNVFYFEPWQVRGDTMLFSIYRIAGVPRRSLSSQEYYRRIYISRWENMVVVPIFDLVESTRELVKKDLFVEKQFMDKCLDYIARLSDQQLTISNVKSYLSSNNWVLFINGAAVKNKQSVDSRDLQLLAQTLLVKEQVARPVMRELREAILTETKPITSLTDVLGLISRKMWKQFANKIAVGGFVGMVGTLIGFYPKKVLTWAKDTPNGPELCYENSHKTKVIVFLSVVYAIGGITLMRRDIRDGLVKKLCDMFDIKRGAHVLDVENPCRYYDINDFFSSLYSASESGETVLPDLSEVKAKSDKLLQQKKEIADEFLSAKFSNYSGSSVRTSPPSVVGSSRSGLGLLLEDSNVLTQARVGVSRKVADEEIMEQFLSGLIDTEAEIDEVVPAFSAECERGETSGTKVLCNLLTPPGFENVLPAVKPLVSKGKTVKRVDYFQVMGGERLPKRPVVSGDDSVDARREFLYYLDAERVAQNDEIMSLYRDYSRGVIRTGGQNYPHGLGVWDVEMKNWCIRPVVTEHAYVSNPDKRMDDWSGYLEVAVWERGMLVNDFAVERMSDYVIVCDQTYLCNNRLILDNLSALDLGPVNCSFELVDGVPGCGKSTMIVNSANPCVDVVLSTGRAATDDLIERFASKGFPCKLKRRVKTVDSFLMHCVDGSLTGDVLHFDEALMAHAGMVYFCAQIAGAKRCICQGDQNQISFKPRVSQVDLRFSSLVGKFDIVTEKRETYRSPADVAAVLNKYYTGDVRTHNATANSMTVRKIVSKEQVSLKPGAQYITFLQSEKKELVNLLALRKVAAKVSTVHESQGETFKDVVLVRTKPTDDSIARGREYLIVALSRHTQSLVYETVKEDDVSKEIRESAALTKAALARFFVTETVLXRFRSRFDVFRHHEGPCAVPDSGTITDLEMWYDALFPGNSLRDSSLDGYLVATTDCNLRLDNVTIKSGNWKDKFAEKETFLKPVIRTAMPDKRKTTQLESLLALQKRNQAAPDLQENVHATVLIEETMKKLKSVVYDVGKIRADPIVNRAQMERWWRNQSTAVQAKVVADVRELHEIDYSSYMFMIKSDVKPKTDLTPQFEYSALQTVVYHEKLINSLFGPIFKEINERKLDAMQPHFVFNTRMTSSDLNDRVKFLNTEAAYDFVEIDMSKFDKSANRFHLQLQLEIYRLFGLDEWAAFLWEVSHTQTTVRDIQNGMMAHIWYQQKSGDADTYNANSDRTLCALLSELPLEKAVMVTYGGDDSLIAFPRGTQFVDPCPKLATKWNFECKIFKYDVPMFCGKFLLKTSSCYEFVPDPVKVLTKLGKKSIKDVQHLAEIYISLNDSNRALGNYMVVSKLSESVSDRYLYKGDSVHALCALWKHIKSFTALCTLFRDENDKELNPAKVDWKKAQRAVSNFYDW
What is the function of this protein?
Is a methyltransferase active in RNA capping and an RNA helicase.  Methyltransferase displays a cytoplasmic capping enzyme activity.  This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus.  Helicase region probably exhibits NTPase and RNA unwinding activities (Potential).
What are the official names of this protein?
Replicase large subunit, 194 kDa protein, RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: VF136_IIV3
Sequence: MVHFMVCGILLGFLVFKISRHLESRRDDGEFAPSTNLVWDLRRDLGNLFYGPNSGPLVGPLEPLNDLNIFNNLKIVEDQESYTLNKKIIHLCTRDLRSKRYYDKNTLMFVVLHELAHVLCRDIGHTDNFSTINQALLDYAIARGYYDPRKPFVKNYCSL
What are the official names of this protein?
Uncharacterized protein 042R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 136R family.
Protein: VF475_ASFP4
Sequence: MDQEESHVISIFETLGAYFINIFYNFLYKNALYKKHSIVTEYQYQVKGYILGVKQNKKLYEKMLDSFYKYFCNITQINSKTLNFSNFVSTIVDSFIPKEYSQSISLEKKESILELLLCDYISNLGTFITTEKMLPFIIKNRKENYHKVTKEMQDYSLTFLLKKRMELYNKFLRKQAYVEPETELEETYARLSSYNRSLLHQIEELTSEKKSLLADLSTLRKKYEKRQSEYRRLVQLLYQQIQRSSTSKSSYPLTKFIETLPSEHFSNEEYQKETPADQKEVVETELLRKQELLTSQELTSKSPNNYPVPHSRTIVSKPSDNYPVPRSRTTKLDFDNSLQNQELHTKNGFSEKDIVEFSQDKPVFKQDKPEEENILANNQDNPEEEDILAIKQDKPEEEDILAIKQDKPEEEDILEFNQDKPEFKEAVLDIKENILEEENQDEPIVQNPFLENFWKPEQKTFNQSGLFEESSYFSNDWSGGDVTLNFS
What are the official names of this protein?
Uncharacterized protein B475L, pB475L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B475L family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: DPP3_MOUSE
Sequence: MADTQYILPNDIGVSSLDCREAFRLLSPTERLYAHHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKDKLGRVILGSKAAQQRPEEVRDLWQTCGDLMFSLEPRLRHLGLGKEGVTTYFSGDCTMEDAKLAQDFLDSQNLSAYNTRLFKVVGQEGKSHYEVRLASVLNTDPALDSELTSKLKRYEFQGNHFQVTRGDYAPILQKVVEHLEKAKAYAANSHQEQMLAQYVESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFERLVASAEQLLKELPWPLAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYAAKREKLTFLEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDKETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLNPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAANWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVRLDRSKIRSVGRPALERFLRRLQVLKSTGDVVAGRALYEGYAAVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSEVQLVEYEASAAGLIRSFCERFPEDGPELEEVLIQLAAADARFWRNQAQEAPPGQA
What is the function of this protein?
Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin.  Also cleaves Arg-Arg-beta-naphthylamide (in vitro).
What are the official names of this protein?
Dipeptidyl peptidase 3, Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, Dipeptidyl peptidase III, DPP III, Enkephalinase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M49 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MURI_CLOBH
Sequence: MSINDKPIGFFDSGVGGISVLKEAFKLLPKEDFLYYGDSKNAPYGTKKVEEVKALTFNATDFLMSKGIKALVVACNTATSVTINDLRENYDIPIIGIEPALKPAVELKKGGKIIIMATPMTLAEKKFANLMDLYKETEDIEPLPCPGLPELIEQGIVSGDVIYNYLKDKFSKYDNEKISSIVLGCTHYPFIEETLKEVTHNKACIIDGSFGTSRELKRQLKNSNMLTEENRVGKVTIFNSREDKDIIDLSYKLFNMK
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PUR9_XYLFT
Sequence: MASDFLPVHRALLSVSDKTGLVELARVLLAYNIELLSTGGTATIIREAGLPVQDVADLTDFPEMMDGRVKTLHPVVHGGLLGRAGIDDAVMAKHGIAPIDLLIVNLYPFEQITAKKDCTLADAVDTIDIGGPAMLRSAAKNFARVAVATSPDQYPDLLAELQAHHGQLSAEKRFALAVAAFNHVAQYDAAISNYLSSVSDMHTTLPLRHEFPTQLNNTFVKMTDLRYGENPHQSGAFYRDVHPQPGTLATFKQLQGKRLSYNNLVDADAAWECVRQFEAPACVIVKHANPCGVAVGTACSDAYEAAYATDPTSAFGGIIAFNRTLDAVTMQSILDRQFVEVLIAPYYDADALAYATKKANVRVLRIPSTGAMNRYDFKRIGSGLLVQSADSLNIHSGALKVVTQLAPTYAQQRDLLFAWHVAKYVKSNAIVYAKDNRTIGIGAGQMSRVYSARIAGIKAADAHLAVTGSVMASDAFFPFRDGIDAAAATGIKAVIQPGGSMRDNEVIAAADEHGIAMVFTGIRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: IL5RA_HUMAN
Sequence: MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF
What is the function of this protein?
Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:9378992).  Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 (PubMed:1495999, PubMed:22528658).  In unstimulated conditions, interacts constitutively with JAK2.  Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway (PubMed:9516124).
What are the official names of this protein?
Interleukin-5 receptor subunit alpha, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5R-alpha, IL-5RA, CDw125.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 5 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GRPE_AQUAE
Sequence: MEKNQKEIEKELEELRKREKELEEKIQKLETIAKNSNLRVAELQREIDYLKERYRRDLEEQRKFCYEKFAYDLLEVMDNFERALEYGRQAQDVKSILLGIEMIYSEMKKIFEKYGIREIPVEGKEFDPYVAEAVEKVETDQYPPNTVVKVIRKGYYIHDKVLRPARVAVAVPPQEEEGEEIT
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAD20_ORYSJ
Sequence: MGRGKVQVRRIENEVSRQVTFSKRRPGLLKKAHEIAVLCDVDVAAIVFSAKGNLFHYASSHTTMERILEKYDRHELLSEGNNVIEEFPELEGSMSYDHIKLRGRIEALKKSQRNLMGQELDSLTLQDIQQLENQIDTSLNNIRSRKEKLLMEKNTILEKKITELETLHTCIRASPTKAAAPPACNTADAFVPNLNICCGDSGEPETVTAPLGWTSSNNGLPWWMLQSSSNGKS
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
MADS-box transcription factor 20, OsMADS20.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDH_KLEPN
Sequence: MKVAVLXAAGGIQALALLLKTSLYDIAPVTPGVAVDLSHIPTDVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQIAKTCPQACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLF
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: OGA_BACTN
Sequence: MKNNKIYLLGACLLCAVTTFAQNVSLQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLSGKQSSKKGMLISIGEKGDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYYALQTFAQLLKDGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGKNKMNTYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPGQDIKWNKEDRDLLLAKFEKMYQLGVRSFAVFFDDISGEGTNPQKQAELLNYIDEKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLNPSIQIMWTGDRVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLLGPVYGNDTTIAKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQTWKDAIRTILPSAAEELECFAMHNSDLGPNGHGYRREESMDIQPAAERFLKAFKEGKNYDKADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQFKLTAEMGEEVLKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPYQPGVKTATRVIKPLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMISNVEQIKNLPLQVKANRVLISPANEVVKWAAGNSVEIELDAIYPGENIQINFGKDAPCTWGRLEISTDGKEWKTVDLKQKESRLSAGLQKAPVKFVRFTNVSDEEQQVYLRQFVLTIEKK
What is the function of this protein?
Can hydrolyze the glycosidic link of O-GlcNAcylated proteins.  Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates (in vitro).
What are the official names of this protein?
O-GlcNAcase BT_4395, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, Hexosaminidase B, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 84 family.
Protein: MDCC_XANAC
Sequence: METLRYRFDGQRGARAGLEHALVGVVASGNLEVLVERVPLEGAMEIDILTAARGFGAIWQAVLDDFAARHPLRDVRISINDVGATPAVVSLRLEQALDVLQGADA
What is the function of this protein?
Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.
What are the official names of this protein?
Malonate decarboxylase acyl carrier protein, Malonate decarboxylase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the MdcC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOH_YERPB
Sequence: MKQLYWYTCGEGDCDLVLLHGWGLNSGVWHCIIDRLAPHFRLHLVDLPGYGRSQDYGAMSLADMAERVAQQAPKQALWLGWSMGGLVASQIALSQPECVRGLITVSSSPCFTARDEWPGIKPEVLAGFQHQLSDDFHRTVERFLALQTLGTESSRQDARLLKSVVLQHQMPDVEVLTGGLEILRTADLRTALSGFTLPFMRVYGHLDSLVPRKVASLLDSAWPQTQSVVMQGAAHAPFISHPNDFAKLILNFAEENKK
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.