PharMolix/UniProtQA huggingface dataset:
Protein: NCHL1_MOUSE
Sequence: MMELPLCGRGLILSLIFLLLKLSAAEIPLSVQQVPTIVKQSYVQVAFPFDEYFQIECEAKGNPEPIFSWTKDDKPFDLSDPRIIAANNSGTFKIPNEGHISHFQGKYRCFASNRLGTAVSEEIEFIVPGVPKFPKEKIEPIDVEEGDSIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQRGDLYFANVEENDSRNDYCCFAAFPKLRTIVQKMPMKLTVNSSNSIKQRKPKLLLPPAQMGSLSAKTVLKGDTLLLECFAEGLPTPHIQWSKPGSELPEGRATIEVHEKTLKIENISYQDRGNYRCTANNLLGKASHDFHVTVEEPPRWKKKPQSAVYSTGSSGILLCEAEGEPQPTIKWRLNGLPIEKHPFPGDFMFPREISFTNLLPNHTGVYQCEASNIHGTILANANIDVIDVIPLIKTKNEENYATVVGYSAFLHCEYFASPKATVVWEVADETHPLEGDRYHTHENGTLEIYRTTEEDAGSYSCWVDNAMGKAVITANLDIRNATKLRVSPKNPRIPKSHVLELYCESQCDSHLKHSLKLSWSKDGEAFEMNGTEDGRIVIDGAYLTISNITAEDQGVYSCSAQTSLDSTSEKTQVTVLGVPDPPGNLHLSERQNRSVRLSWEAGDDHNSKISEYIVEFEGNREEPGKWEELTRVQGEETDVVLSLAPYVRYQFRVTAVNEVGRSHASLPSDHHETPPAAPDKNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYKVSWKPQGAPEEWEEEIVTNHTLRVMTPTVYAPYDVKVQAINQLGSSPDPQPVTLYSGEDYPSTAPVIQRVDVMNSTLVKVTWSSIPKETVHGLLRGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDPFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPSFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYELGELNEINVTTPSKSSWHLSNLNSTTKYKFYLRACTSRGCGKPISEEGATLGEGSKGIRKITEGVNVTQKIHPVEVLVPGAEHIVHLMTKNWGDNDSIFQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLILLTICFVKRNRGGKYSVKEKEDLHPDPEVQSAKDETFGEYSDSDEKPLKGSLRSLNRNMQPTESADSLVEYGEGDQSIFNEDGSFIGAYTGAKEKGSVESNGSSTATFPLRA
What is the function of this protein?
Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity.  Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death.  Plays a role in neuronal positioning of pyramidal neurons as well as in regulation of both the number of interneurons and the efficacy of GABAergic synapses.  May play a role in regulating cell migration in nerve regeneration and cortical development.  Potentiates integrin-dependent cell migration towards extracellular matrix proteins.  Recruits ANK3 to the plasma membrane.
What are the official names of this protein?
Neural cell adhesion molecule L1-like protein, Cell adhesion molecule with homology to L1CAM, Chl1-like protein, Close homolog of L1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Soluble forms produced by cleavage/shedding also exist. SUBCELLULAR LOCATION: [Processed neural cell adhesion molecule L1-like protein]: Secreted, extracellular space, extracellular matrix.
Protein: DAPF_CAUVN
Sequence: MSRTFLKMNGLGNDFVVIQTLTEAFDPTPEQIRAIAKRPGVDGKGGIGCDQVIAIDPPRAEGASAYVRFWNSDGEVAGACGNGTRCVAWLLMQSAGKDAVAFDTVAGRLSGVAAGDKLVTVDMGPPGLDWTQIPLAEEMNTERVELQVGPIDAPLVHTPVCVSMGNPHVVFFVDAPVTDDFARGTGSLVEHHPLFPEGVNVGFAHIASRDHIRLKVWERGAGLTQACGTGACAAQVAAVRRGLTDRKARVEFDTGSLTIEWRESDGHVIMTGPITMEYAGKLPELVAA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_PSEE4
Sequence: MANNDQKRDEGYIEKLVQVNRVAKTVKGGRIFTFTALTVVGDGKGRVGFGRGKSREVPAAIQKAMEAARRNMIQVDLKGTTLQYATKAAHGASKVYMQPASEGTGIIAGGAMRAVLEVAGVQNVLAKCYGSTNPVNVVHATFKGLKAMQSPESIAAKRGKTVEEIF
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MOAC_STAAT
Sequence: MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RF1_RUMCH
Sequence: MFDKLQAAEDRYEEISHKLSDPDVINNQDEYKKYMKECSDLEEIVQKYREYTKVTKEIEEARELLEQTLDKDFREMVQQEFQEAQEKLEVIKRQLKILIVPKDPNDDKNVIVEIRGGAGGEEAALFAGVLFRAMAKYAEKKRWKYEILDSNPTELGGFKEVVFTIEGKGAYSRLKFESGVHRVQRVPSTESSGRIHTSTITVAVLPEVEEVDVDINPSDLRIDTYRASGAGGQHINKTDSAIRITHMPTGIVVSCQDERSQHKNKDKAMKILRSKLYEIAQEQQINEVAQDRKNQVGTGDRSERIRTYNYPQGRVTDHRINLTLYKLEQVLDGDLDELIDALITTDQSEKLGSGSDDEG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_AZOPC
Sequence: MDKNTIIGFILIFWVLFGFAYLNHNRPIQEQLEKNPPMSANSVKKEFSNPISEIQSSDIYGNFAASTKGTETFVTIQNALMEIKLSTKGGRIYSVRLKKYTNYKNEPLYLFEGDESAFNIIFISSNNKVLNSEDFYFEIVSNSELETILRLNAGKNRYIDFVYTLHPDDYMVDWKLVSHNIQTELSHSMHTLNIQWMQKIRQQEKGRKFEERYARLTYKFLTDDIEQLRETKDDVRNVPNKLKWIGYKDQFFSSVFIVHSNFESAKLDSKYLTYGAYIKEYSTSTSIPYNIANIEPIKFNFYFGPNDYSLLKSYDKTKLKEQNLELEKLVPLGWSLFRAINKCLIIPIFNWLTNGENVNLGLAILILTLIIKIALFPLTYKSFISSAKMRVLKPQVENINIKYSGQEKALIRQQKTMELYRQVGVNPMTGCFPILLQMPFLIALFMFFPSAIGLRHQSFLWANDLSTYDTLIQWSTDIPFIPRFLGNHISLFCLLMSLATILNTRYNTMYQQNIGQEQFPGMKLTMYFMPVVMFFFLNSYPAGLNYYYLISTLITIMQTIIFRGLVNELNLLAKLEANKKKSKLVKKKFGFMDRLEEFQRKQQELLKKKRKR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y840_BRUA2
Sequence: MKNLFRTAALMVPLSLALAYGAQAKEIPIGKPQLLGGMEIAAVYLQPIEMEPEGMMRPAKDSDVHLEADIKAAKDNTNGFAEGDWVPYLVVSYELTHLDNGKVQKGDFMPMVANDGPHYGDNVKLDGPGKYKLKLFVSPPSANQHAHFGRHVDKETGVGPWFKPVTAEYEFVYAGTGKKGAY
What are the official names of this protein?
UPF0423 protein BAB2_0840.
What is the protein family that this protein belongs to?
Belongs to the UPF0423 family.
Protein: SP39_BRUME
Sequence: MHKLLKLAAMGTAACALLAGMAPVANAQEKQNVEVLHWWTSGGEASALEVLKKDLESKGISWTDMPVAGGGGTEAMTVLRARVTAGNAPTAVQMLGFDIRDWAEQGALGNLDTVASKEGWEKVIPAPLQEFAKYDGHWIAAPVNIHSTNWMWINKAALDKAGGKEPTNWDELIALLDNFKAQGITPIAHGGQPWQDATIFDAVVLSFGPDFYKKAFIDLDPEALGSDTMKQAFDRMSKLRTYVDDNFSGRDWNLASAMVIEGKAGVQFMGDWAKGEFLKAGKKPGEDFVCMRYPGTQGAVTFNSDMFAMFKVSEDKVPAQLEMASAIESPAFQSAFNVVKGSAPARTDVPDTAFDACGKKAIADVKEANSKGTLLGSMAHGYANPAAVKNAIYDVVTRQFNGQLSSEDAVKELVVAVEAAK
What is the function of this protein?
Part of a binding-protein-dependent transport system for a sugar.
What are the official names of this protein?
Probable sugar-binding periplasmic protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NGA2_ARATH
Sequence: MNQEDKEKPIEEASSSMEREHMFDKVVTPSDVGKLNRLVIPKQHAERYFPLDNSTTNDSNKGLLLNFEDRSGNSWRFRYSYWNSSQSYVMTKGWSRFVKDKKLDAGDIVSFQRDSCNKDKLYIDWRRRPKIPDHHHQQFAGAMFPRFYTFPHPQMPTNYETHNLYHRFHQRDLGIGYYVRSMERSHPTAVIESVPVMMQRRAQVASMASRGEKRLRLFGVDMECGGGGGSVNSTEEESSSSGGSIPRGRVSMVGAGSLLQLRLVSSDDESLVAMEAASLEDHHFFTKKGKPSLSFDLDR
What is the function of this protein?
Regulates lateral organ growth.  Functionally redundant with NGA1, NGA3 and NGA4.
What are the official names of this protein?
B3 domain-containing transcription factor NGA2, Protein NGATHA 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL27_ROSCS
Sequence: MAHKKGVGSSRNGRDSNPKMLGVKRFGGERVKPGMIIVRQRGTKFKPGANVGLGRDYTIYSLIDGVVTFEQHSRNQKRVSVYAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RNH_RHIEC
Sequence: MKHVDIFTDGACSGNPGPGGWGAVLRYGEVEKELCGGEAETTNNRMELMAAISALQALKSPCEVDLYTDSAYVKDGISKWIFGWKKNGWKTSDKKPVKNAELWQALEEARNRHKVTLHWVKGHAGHPENERADELARRGMEPFKKGKAVSF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_ACET2
Sequence: MSKKKVMVGMSGGVDSSVAAAILLEQGYEVIGATMQIWPDTDEETKLVEGGCCSLSAVDDARSVANKLGIPYYVLNFKDIFEKSVINYFKDEYLKGRTPNPCIACNRFVKFESMLNKALSMGIDYIATGHYAIITYDDNKKRYLLKKSVTQQKDQTYALYNVTQEQLKHILMPIGNFTKEQVRAKAKELGLYVASKPDSQEICFVNDNDYGKFIEENTDKEIKPGYFVDTKGNILGKHRGIIHYTVGQRKGLGIALGKPMYVVRIDAENNTVVLGDENEVYSKELTAYDLNFISIDKLEEPMRVKAKIRYSAKEADAVIYPLEDGKVRVVFDTPQRAVTPGQSVVFYDGDIVVGGGIIQ
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPC1_RICCN
Sequence: MLKSVRLYIPSIAVMILSSNIAIANKNYDAGNATPLRQVADLIDNQITNIDNLFKNRLSLYESNSIKSNFITKDKQYIIVMEVPGFDKSQIKVKVNGNKLFITGNIEEKNKADYSDNYMNKNFNYVISLYEDVDQANISSSLKNGILTIILPRIEIKEQEAREIVID
What are the official names of this protein?
Small heat shock protein C1.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: MTNA_CROS8
Sequence: MQTLQTTSLRVVDNKLWILDQQALPQQKNWLPADNTEALVGHIHALRVRGAPLIGLSASLLLALLAEHGMTRDALGQALEVLRAARPTAVNLMNNLDRMKQALTQPDFVAALGAEALRLVQEDRELCERIARAGSELVKPGSRLLTHCNTGGLATAGVGTALGVIARAHEAGKVANVWVDETRPLLQGGRLTAWELGELGVPYQLITDSMAASLMAQGQVDAVWVGADRIAANGDVANKIGTYSLAVLAKFHNVPFYVAAPQTTLDPACPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPEDARVYNPAFDVTPAALISGWVLDSGVVTPEDVANGRFAG
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: THIC_BURCM
Sequence: MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQGWIEARGDTEVLDGLSSQYGLERAADPATADLRFPGLHRNPRRAQPGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYIESLKSSGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEIARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: COX2_BOSIN
Sequence: MAYPMQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDSYMIPTSELKPGELRLLEVDNRVVLPMEMTIRMLVSSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMSSRPGLYYGQCSEICGSNHSFMPIVLELVPLKYFEKWSASML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VINT_LAMBD
Sequence: MGRRRSHERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELFSGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEGHITTNHVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTALHIDALGISMKETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.  In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
What are the official names of this protein?
Integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: ENV_FRSFB
Sequence: MEGPAFSKPLKDKINPWGPLIVLGILIRAGVSVQRDSPHQVFNVTWRVTNLMTGQTANATSLLGTMTDAFPKLYFDLCDLIGNDWDETRLGCRTPGEGKRARTFDLYVCPGHTVPTGCGGPREGYCGKWGCETTGQAYWKPSSSWDLISLKRGNTPKDRGPCYDSSVSSGVQGATPGGRCNPLVLKFTDAGKKASWDAPKVWGLRLYRSTGTDPVTRFSLTRQVLNIGPRVPIGPNPVISDQLPPSRPAQIMLPRPPQPPPPGTASIVPETAPPSQQPGTRDRLLNLVNKAYQALNLTSPDKTQECWLCLVSRPPYYEGVAVLGTNSNHTTLISTIMGLLIILLLLLILLLWTLHS
What is the function of this protein?
This envelope-like membrane glycoprotein is responsible for ligand-independent activation of the erythropoietin receptor EPOR leading to the abnormally rapid proliferation of erythroid precursor cells.  In the first stage of Friend disease, constitutive activation of the EPOR by gp42 causes uncontrolled, polyclonal proliferation of infected erythroblasts, leading to polycythemia (massive increase in the number of mature red cells).  Host susceptibility to SSFV-induced erythroblastosis usually depends on the expression of the truncated isoform of MST1R receptor tyrosine kinase (MST1R isoform sf-Stk), but the deletion mutant BB6 apparently can overcome its absence.
What are the official names of this protein?
Glycoprotein 42, gp42.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Virion membrane; Single-pass type I membrane protein. Note=The envelope-like membrane glycoprotein gp55 is defective in its transport to the cell surface and remains associated predominantly with the rough endoplasmic reticulum (RER) membrane. It is almost not incorporated into virions. Host cell surface expression appears to be a prerequisite for its leukemogenicity (By similarity).
Protein: GLPK_ACIET
Sequence: MTYLLALDQGTSSSRSIVFDERGRIVAQAQRELPQIYPRPGWVEHDPREIWRTQLATAQDALREARITAQDVRALGITNQRETTVLWNRRTGQPVHHAIVWQDRRAEPACAQLREQGHAAAIQAKTGLLIDAYFSGTKLQWLLDHVPGARDAAEAGELAFGTVDSWLIWQLTGGTRHVTDVSNASRTMLFNVHTNQWDDELLQLLRIPRALMPEVLPSASDFGATDAALLGGPIAIGGVAGDQQSALFGQACFTAGMAKNTYGTGCFMLMHTGSRFQKSENGLLTTSAAQASRSPEYAMEGSVFVGGAVVQWLRDGLRAISASSEVQALAESVPDSGGVMMVPAFTGLGAPYWKPDARGTITGLTRGTTIAHIARAALESIAYQSAALLAAMSRDAVAAGGAPVSELRVDGGACVNDLLMQFQADLLGIPVVRPAVVETTALGAAYLAGLASGVYASTDELSALWQAERRFTPTLPRSQAEALMARWEHAVAQAVLPG
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: COX5C_ORYSJ
Sequence: MAGGRIAHATLKGPSVVKEICIGLTLGLVAGGLWKMHHWNEQRKTRSFYDMLEKGQISVVVEE
What is the function of this protein?
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
What are the official names of this protein?
Cytochrome c oxidase subunit 5C, Cytochrome c oxidase polypeptide Vc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5C family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: CIGB_DICDI
Sequence: MKESEDIIINNQNRCTLHPNKNLEFLCLDCKFMPCCSLCTSRKGEHHGHKTDSLESSASNIHSLINDFKDNIYPKLIERKENDQILLKESNETFKEIQSQNDDNNNLLKNEFKQIHNILSFVELDIEKQLSTNLDQNILINTIITSSINNDNKIISTILNNNNNSIIDKLNYFTQINNQQDNDDNDDCYQIDTDTIELIKQYQNSLLILKNSNNINNLTKLKEYNNQILKFDNQTINNIKNSFKSIYSFGDIPNDAIDYNINNNNNNNNNNNNNNNNELNNSNNKNEFIKILNHNFYIYSESDESSFLTDDFESLAFKDNCNILSKLKKLPNNVLLLSGFNQKLTKGIIPEGVKVLYIGDIKQELIIDSIPNTVTTVGLWYGFNQKLTKGIIPEGVKELRLGDIKQELIIDSIPSTLTTVILCDGFNQKLTKGIIPEGVKVLYIGDIKQELIIDSIPNTVTRVRLLDGFNQKLTKGIIPESVKELHIGNIKQELIIDSIPNTVTTITLCDGFNQKLTKGIIPEGVKELYIGNLKQELIIDSIPNTVTTVRLCDGFNQKLTKGIIPEGVKELYIRDIKQELIIDSIPNTVTTVILCDGFNQKLTKGIIPEWVKGLCLGDIKQELIIDSIPNTVTTVRLLDGFNQKLTKGIIPESVKELYIDDIKQELIIDSIPNTVTTVRLLDGFNQKLTKGIIPEWVKELHIGDIKQELIIDSIPNTLNNVYIYKSCKKLIYSFVPVNVKIVNI
What are the official names of this protein?
FNIP repeat-containing protein cigB.
Protein: SSRP_RICCK
Sequence: MTRYKKVIAQNKKALFNYFIEERLEAGIVLKGSEVQSLRQGKASIEESYAGDTGHELFLYNCHIAEYEKANKFNHATRRPRKLLLHTKEMKKIIGKIKIKGYTLVALSMYFNKKNKVKVELGLAKGKKLYDKRESIKEKDWQRDQSRLIRQK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MP2K2_XENLA
Sequence: AQWGLLHCSLHLVANILTMATSNPSGSSGSSAGLGFQGQSQQHSTVNSMQGKRKALKLNFANPAFKSTAKFTLNPTIQSTHVMHKLDAIRKLETSYQKQDLRTSGAKALSTNEQATKNRLERLRTHSIESSGKLKLSPEQHWDFTAEDLKDLGEIGRGAYGSVNKMSHTPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMATSFDKFYKYVYSFLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDTNGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFTSFVNQCLTKDESKRPKYKELLKHPFILMYEERTVDVAGYVGKILEQMPVSPSSPMYVD
What is the function of this protein?
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases.
What are the official names of this protein?
Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, MAPK-ERK kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: NANK_SHIFL
Sequence: MTILAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDALSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIAINDAQAAAWAEYQALEGDITDMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLADPHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADARTIFTRAGQGDEQAQQLIHRSARTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVEMYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: DSBB_BURMA
Sequence: MNNLTLSLRRERRLLVLLALVCLALLAGALYLQYVKNEDPCPLCIIQRYFFVLIAVFAFIGAGMASGAGVAVTEALIVLSAAAGVGTAARHLYVQLNPGFSCGFDALQPVVDSLPPARWLPGVFKVAGLCETVYPPIFGILLPGWALIAFVLIAVPVAVSLLRHRGRLR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTS_CHLRE
Sequence: MSGIPRSLLGQCAVALLGANARSGLTLHHAFAAYSSAAAPAQSAALIKQLRERSGAPIADVKSMLVEHGWDMDKAYEALRKKGLAAAAKKASRHAAEGLVGASFAASAASSGGSSSSEASTSGGGRGSVVVVELNSETDFVARNELFQKLLREVMGAAHALGPAAALMSARTASGPSVSEAVTALAVQVRENVRLRRAFRVDSGAGGLVFPYVHQAAAPGLGKLASVVVLAPEPDDKAQPLVLDKVVEGRLGKLLSDWCLEAQRYVLEDELTVDKLMARLKKEVGQPVRVASFLRVQCGEGLGAKAGGGDFAAEVARIVSEA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PNCB_SHIB3
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQIQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYKKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.