PharMolix/UniProtQA huggingface dataset:
Protein: Y292_RICCN
Sequence: MNKSLTEKISAFIITKNESTRVARAINSVKNITDEVIVVDSESTDDTVAIAEKLGAKVVIKPWLGYVGQKSFAESLCVNDWVLNIDADEELSKELQDEIEYIFASHNQDRYLAYQIKLLIMHRNDQKPRMFAPFNKCTRLYNKKFASFANTVNSTTHDSVIFNKDVDFAGKIYLLNEAAYHYSGTSIEQLVTKANFYSNEQAKDLVKQGKKLSNFRLTTEMIWWFFKAFFIRRYFVFGVDGFVDSIIFAFARFLRLTKLRESSLKSKNVIASDYKERGNFMK
What are the official names of this protein?
Uncharacterized glycosyltransferase RC0292.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. WaaE/KdtX subfamily.
Protein: RS17_DESHY
Sequence: MERTQRKVRMGKVVSDKMDKTVVVAVEMKVRHPLYHRTITQTKKFKAHDENNEAKTGDTVVIMETRPLSKDKRWRLIEITERAVAL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CAV1_SAIBB
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYIHTVCDPLFEAIGKIFSNVRIGLQKEI
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: SYT_STRPN
Sequence: MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKLIDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGFYYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIEEHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIYGTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRELERYIVNKELVSGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPMNCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTPEQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAALDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADGEDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVAKKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQTVSVDNFVQAILADIANKSRVEK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKG_BURMA
Sequence: MTRSNVVAATRTVPIDVPEYVKHRGLIDWVARIAELTEPDRVVWCDGSQQEYDRLCDAMVEQRTMVRLNPAKRPNSFLALSDPSDVARVEDRTFICSEHRDDAGPTNHWVAPAEMRATLNGLFRGAMRGRTLYVVPFSMGPLGSPIAHIGVELSDSPYVVVNMRIMTRMGRAVLDALGERGEYVPCVHSVGRPLAAGEQDVPWPCNPTKYIVHFPESREIWSFGSGYGGNALLGKKCFALRIASTMGRDEGWLAEHMLILGVTSPEGRKYHIAAAFPSACGKTNFAMLIPPKGFEGWRVTTIGDDIAWLKPGRDGRLYAINPEAGYFGVAPGTGEKTNPNALATLRENVIFTNVALTEDGDVWWEGLTDTPPARLTDWQGNAWTPEIGRETGRKAAHPNSRFTAPASQCPSIDDDWENPGGVPIDAFIFGGRRSTTVPLVTEARDWIEGVYMAATMGSETTAAAAGQQGIVRRDPFAMLPFCGYNMSDYFSHWLALGEKLAAAGATLPKIYCVNWFRKDADGRFAWPGFGENMRVLKWMLDRIDGRGEGVEHAFGVTPRYEDLHWAGLAFSPAQYAQVTSMNPDEWRAELALHAELFDKLSARLPDALAETKARIEKRLGG
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RODL_NEUCR
Sequence: MQFTSVFTILAIAMTAAAAPAEVVPRATTIGPNTCSIDDYKPYCCQSMSGPAGSPGLLNLIPVDLSASLGCVVGVIGSQCGASVKCCKDDVTNTGNSFLIINAANCVA
What is the function of this protein?
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures.  Important for the formation of hydrophobic rodlet layers of asexually-produced spores.
What are the official names of this protein?
Hydrophobin, Blue light-induced protein 7, Clock-controlled gene protein 2, Rodlet protein.
What is the protein family that this protein belongs to?
Belongs to the fungal hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: SYI_MALP2
Sequence: MSDYKKTLSMPNTNFEMKANLSVKETKIQENWVLEKIEKKILAKNKSNTPFIIADGPPYANGDLHTGHALNKILKDIILRFKASVGFYTKYIPGWDTHGLPIEQEMAKRGLNKNANQTITEKRKNCKNFAIENVYKQRDQFRRLGILSEMDEIYVTCDLDYVIRQIKIFNKMLSKGLIYQDLKPVYWSWSSQTALADAEIIYQDVESDSIYVSLEILDKNEFVSKGDKVIIWTTTPWTLPSNLAIAANPKVTYCRVQVENSVYVISKNLVEKLAETLEWTNYEILSEFSGKKLENLPYKSPISDKKCKIIVDGYVSDSDGTGLVHNAPGFGHEDYLACKKYNIKPYCPIDNLGKFTGEVNDKELAGLFYKDANPIIIERLAKKKLLLKASKFTHSAAHDWRTKKPVIYRATKQWFVNIDKISKEIVAALNKVKSIDNTIIKKIKEMVLNRQEWCISRQRIWGVPICIIYDKDYNPILDPKLLNNIVDILNDEGINAWYNEDAKYFLTDSYNTSKKYIKETDIMDVWFDSGTSYSVLQADKLGYPADLYFEGKDQFRGWFNSSLITSVAAFKKSPYKELLTHGFVLDENGNKMSKSLGNIIDPLQVCKEYGADVLRLWVASVDFSKDVSISKDIIAQNAELYRRIRNTLFRFILGNLNGFNLKKLRGAKYSEADLYVLSCLSNDIKTIKACYDKYDFKQIVKIVSKNVADLSSWYFDYIKDPLYCEKEDNEQRIAIQATLYQLLDSYLRILAPIIPHTCEEAYEFFDKKDKQKSVHLEGFTNFKIDSKYKVDFKKWEEFFDLKDKVYSEIEKTRNEKVINSKGQAHITIHSKSLPFDEQTLERYLGVAKVEFKVKEKDGTTIKVKNSKYARCERCWNYYPTNLIANELCERCKKVIGNKKI
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYQ_VIBVY
Sequence: MSEADARPSNFIRQIIDKDLADGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGKCNLRFDDTNPEKEDIEYVESIKNDVSWLGFEWDDEICYSSNYFDKLYEYAVELINKGLAYVDELSPEQIREYRGTLTAPGKPSPYRDRSAEENLALFEKMRDGGFEEGKACLRAKIDMASSFMVMRDPVLYRVRFASHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFMDNRRLYDWVLDNITIDCRPHQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTISGLRRRGFTPASIREFCKRIGVTKQENMIEFSSLESCIRDDLNENAPRAMAVLDPVKLVIENFPAGEVENLTVANHPNKPEMGEREVPFSREIWIEREDFREEANKKYKRLVLGSEVRLRGAYVIKAERVEKDDEGNITTIFCTYDSETLGVNPADGRKVRGVIHWVSADKGVPAEIRLYDRLFTVPNPAAADDFASTINPESLTVMNGFVEPSLVEAEAEKGYQFERMGYFCADSKDSSKEHLVFNRTVGLRDTWAKIEAK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTUB_CHLTR
Sequence: MKKRSSRKLAQVIGRKTGNYFPASIEGETKKEHKHHYSTASKEKESLRKRAKEFDVLVHSLLDKHVPQNSDQVLIFTYQNGFVETDFHNFGRYSVKL
What are the official names of this protein?
Late transcription unit B protein.
Protein: RL36_STRPI
Sequence: MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DSBB_SHELP
Sequence: MSALTRFAQSRLAWTLLLLTAVGLEACALFFQHVMKLDPCVMCIYQRLAVLGVLTAGLIGVVGHQFRLLRFLGVLLWGVSAAWGLKLALELVEMQTNPSPFSTCSFLPEFPEWMPLHEWFPSVFLPTGMCTDIPWEMFGITMSQWMVVAFSTYLIALVVFIVPALMPTKKA
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GYRA_MYCSM
Sequence: MTDTTLPPEGEAHDRIEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMYDSASSDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSRGIAVGMATNNPPHNLGELAEAVYWCLENYEADEEATCEAVMERVKGPDFPTSGLIVGTQGIEDTYKTGRGSIKMRGVVEIEEDSRGRTSIVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSSDRVGLRIVVELKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQLIRLYVDHQLDVIVRRTRYRLRKANERAHILRGLVKALDALDEVIALIRASQTVDIARAGLIELLDIDDIQAQAILDMQLRRLAALERQKIVDDLAKIEAEIADLEDILAKPERQRGIVRDELKEIVDKHGDARRTRIVPADGQVSDEDLIAREDVVVTITETGYAKRTKTDLYHSQKRGGKGVQGAGLKQDDMVNHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAFQPEERIAQVIQIKSYEDAPYLVLATRNGLVKKSKLSDFDSNRSGGIVAINLREGDELVGAVLCSAEDDLLLVSANRQSIRFSATDEALRPMGRATSGVQGMRFNEDDRLLSLNVVRPDTYLLVATSGGYAKRTSIDEYSVQGRGGKGILTIQYDRKRGSLVGALIVDDDTELYAITSTGGVIRTAARQVRKAGRQTKGVRLMNLAEGDTLIAIARNGRGRGGRVDQRIRRGHRRVTRGVMETLRSRKVLGPS
What is the function of this protein?
Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1463_STAA8
Sequence: MVKTVYVTGYKSFELNIFKDDAPEVHYLKQFIKHKIEQLLDEGLEWVLIQGQMGIELWTAEVVIELQRTYDSLKFAVITPFQGHTEKWNEHNQSKYANIIKHADYVDSIFHTSYQGPFQFKQADQFMLEHSDQTLLIYDEEQEASPKFFKQMLVDFMDKTNYTCDIVTFDELTAFINDLQWSEDQSF
What are the official names of this protein?
UPF0398 protein SAOUHSC_01463.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: DISA_BACAH
Sequence: MEENKQRVKSMINILQLVAPGTPLREGIDNVLRAQTGGLIVLGYNEQIKSIVDGGFHINCAFSPASLYELAKMDGALILNETGSKILIANAQLVPESSIDSIETGMRHRTAERVAKQTGSLVVAISQRRNVITLYQGNLRYTLKDIGVILTKANQAIQTLEKYKAVWNDGITNLGILEFEEVVTMSEVVHVLHSVEMVLRIKNEILSYIHELGTEGRLIRLQLTELLADLEAEAALLIKDYYQEKTQDHHQILKKLQELANTQLLEDSDLVKLLGYPGQTSLEESVTPRGYRITSKISRVPPLIIENLINRFKTLQGVCRATINELDDVEGIGEVRAKKIREGLKRIQEHLYMSRHN
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation.  The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: MGSA_ALISL
Sequence: MKKTTRIVPAHKHIALVAHDNYKAELLRWVKENKEALQGHFLYATGTTGHLLSKETGLAIKSLLSGPMGGDQQLGALISEGKIDMMIFFWDPLNAVPHDPDVKALLRIATVWNVPVAMNRSSAKFMISSPRMTQEIEIEIPDYPAYLAERI
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: SYC_SHEWM
Sequence: MLKLYNSLTRQKEEFKPLQPGKVGMYVCGITIYDLCHIGHGRTFVAFDMIVRYLRYSGYDVNFLRNITDVDDKIIKRAAENKESCDSLTERLIGEMHKDFDSLNMKRPDFEPRATLHMAEIIEMVEKLIEKEHAYVSSNGDVLFSVSSFPEYGRLSGQNLEQLQAGARVEVEDSKRDPMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGQHFDIHGGGSDLQFPHHENEIAQSCCAHNTPYVNYWMHTGMVMVDKEKMSKSLNNFFTIRDVLAHYDAATIRYFLLSGHYRSQLNYSEDNLKQAKSALARLYTALKDLDLTVEPAAAENFVSKFKQAMDDDFNTPEAYSVLFDMVREVNRLKVTDLAQASALAVRLKELAGVLGILEQDVDSFFKGESNDAEVAEVEALIAERNRARAEKDWPAADIARDGLNALGVILEDGPEGTTWRKK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_SALDC
Sequence: MTLLGTALRPAATRVMLLGAGELGKEVAIECQRLGIEVIAVDRYPDAPAMHVAHRSHVINMLDGEALRHVITEEKPHYIVPEIEAIATDTLRELEGEGLNVVPCARATQLTMNREGIRRLAAEELGLPTSTYRFADSEASFHDAVAAVGFPCIVKPVMSSSGKGQSFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQQDGDYRESWQPQQMSELALKRAQEIARHVVLALGGHGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGMPVGAIRQYGPAASAVILPQLTSQNVTFDNVHAAVGAGVQVRLFGKPEIDGTRRLGVALATGENVEEAVIRAKKAASRVTVKG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: PTH_EXIS2
Sequence: MKCIVGLGNPGAKYTNTRHNIGFLAIDALAKEHGIKLTESKFKAVFGTGMIKGERVVLVKPLTYMNLSGEAVRPLLDFYKIAVEDVLVIYDDLDLPLEKMRLRSKGSAGGHNGVKSLIQHLGTQDIKRLKLGVGRPPAPIQVIDWVLMPFAKSEQTTLQHVLSDSVNIATDFIDTPFLALMNRYN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR2_STAA8
Sequence: MTATWSVNKKIFLQNAITVKNNQPLMAVVKNNAYHYDLEFAVTQFIHAGIDTFSTTSLREAIQIRQLAPDATIFLMNAVYEFDLVREHQIHMTLPSLTYYYNHKNDLAGIHVHLEFENLLHRSGFKDLNEIKEVLKDHHHNQNAKMIISGLWTHFGYADEFDVSDYNVERSQWMEIVEALLSEGYQFDLIHAQNSASFYREGQILLPHHTHARVGIALYGSRPYSSLNQHDIVQSLTLKAHVIQVREVQAGDYCGYSFAFEVTKNNTKLAVVDIGYGDGILRTRAKHEALINGKRYPIRALMMSHMFVEVDGNVHAQDEVILYNNDIRIDEYTFKGVGANSEQLSAMNHDSLKKEYISNDC
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase 2.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: HPAB_THET8
Sequence: MARTGAEYIEALKTRPPNLWYKGEKVEDPTTHPVFRGIVRTMAALYDLQHDPRYREVLTYEEEGKRHGMSFLIPKTKEDLKRRGQAYKLWADQNLGMMGRSPDYLNAVVMAYAASADYFGEFAENVRNYYRYLRDQDLATTHALTNPQVNRARPPSGQPDPYIPVGVVKQTEKGIVVRGARMTATFPLADEVLIFPSTLLQAGSEKYALAFALPTSTPGLHFVCREALVGGDSPFDHPLSSRVEEMDCLVIFDDVLVPWERVFILGNVELCNNAYAATGALNHMAHQVVALKTAKTEAFLGVAALMAEGIGADVYGHVQEKIAEIIVYLEAMRAFWTRAEEEAKENAYGLLVPDRGALDGARNLYPRLYPRIREILEQIGASGLITLPSEKDFKGPLGPFLEKFLQGAALEAKERVALFRLAWDMTLSGFGARQELYERFFFGDPVRMYQTLYNVYNKEPYKERIRAFLKESLKVFEEVQA
What is the function of this protein?
Utilizes FADH(2) supplied by HpaC, to catalyze the hydroxylation of 4-hydroxyphenylacetic acid, leading to the production of 3,4-dihydroxyphenylacetic acid (DHPA).
What are the official names of this protein?
4-hydroxyphenylacetate 3-monooxygenase oxygenase component, 4-HPA 3-hydroxylase, 4-HPA 3-monooxygenase large component.
What is the protein family that this protein belongs to?
Belongs to the FADH(2)-utilizing monooxygenase family.
Protein: DNAJ_CHLFF
Sequence: MDYYDVLGVSKTASPEEIKKAYRKLAVKYHPDKNPGDAEAEKRFKEVSEAYEVLSDAQKRESYDRYGKDGPFAGAGGFGGAGMGNMEDALRTFMGAFGGEFGGGGSFFEGLFGGLGEAFGMRGDPAGARQGASKKVHITLTFEEAARGVEKELLVSGYKTCTTCSGSGAANERGIKCCERCKGSGQIVQSRGFFSMASTCPECGGEGRIITDPCSNCRGQGRVKDKRNVHVQIPAGVDSGMRLKMEGYGDAGQNGAPSGDLYVFIDVEPHPVFERRGDDLILELPIGFVDAALGMKKEIPTLLKEGTCRLTVPEGIQSGTILKVKNQGFPNVHGRGRGDLLVRVSVETPQNLSEEQKELLRKFSSTEKAENFPKKRGFLDKIKGFFSDFTV
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_KOCRD
Sequence: MTRNGLSHAQDDLWPAPFRHGSPVSGTVAVPGSKSLTNRYLVLAALASEPSLVRRPLHSRDSALMVAALQTLGAAVTPLPDPGPFGPDLRIDPVRRSAPAADPVRIDCGLAGTVMRFVPPLAALHTGQVDFDGDDAARVRPMGPVLDGLRQLGVHVVDQGRAALPFRVLGTGSVPGGTVTIDASGSSQFVSALLLAAVRFDSPLVLRHDAPGGVPSLPHVEMTLQVLRDAGVDARRVDERSWRVVPGDVAGLDVTVEPDLSNAGPFLAAAVATGGTVSIPDWPQHTTQGGDHWRHILPRFGADVTLREGVFTVTGPRELRGVDLDLSEAGELAPTVAALCALASGPSRLRGIAHLRGHETDRLAALSTELNGLGGAVTETLDGLAIEPTALHGGVFHTYQDHRMATAGAILGLRVPGVQVADIATTAKTLPEFPRMWAELVGSEG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TREF_SHIFL
Sequence: MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKMIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRT14_KOMPG
Sequence: MNKFSSDSSRTTAQSTINKLLVNLIPGSQLNDAKVAKKAKKSSSAKIISDQIGSRMEFKRNEEKRRKFLKQNNLKKRKMKRKSKDLEAQLERIARLSNIKELQQMSEDSNDPLLDQVIDKKITALLSWTTDNSELGTEIEKLKKDILNTDNEEVRRRKSYRDEEREEAEFRSEVEKGSIAYPGLTPGLAPVGLSDDEDDEEEDESDGFDKEEEEDQFSE
What is the function of this protein?
Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription 14.
What is the protein family that this protein belongs to?
Belongs to the RRT14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CYC6_ANAVA
Sequence: ADSVNGAKIFSANCASCHAGGKNLGVAQKTLKKADLEKYGAYSAMAIGAQVTNGKNAMPAFKGRLKPEEIXXVAAYVLGKAEAEWK
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: MIAA_NAUPA
Sequence: MFAIIGPTASGKSDLAIKLALKLNYEILSLDSLSIYKEIDIASAKPSKEELSKVKHYGVNEIYPNEKFDVMKFIEIYKKIPHKNIIIVGGTGFYLKAMLEGISQMPEITDEIKKKAKQKDYAFFESVDPDFASKISPNDTYRIQKGLEIYFATKTPPSVYFKNNPPKPVLPDIPIFEIAVDRSVLRERIKKRTDKMFNSGLIDEVAYLEKKYRDRRLPALKAIGIKEVLDYFNGKYTLKTLKEKIITNTARLAKRQQTFNKTQFKKKISAPLEELEEIILSEIK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: AROK_RHOJR
Sequence: MAPKAVLVGPPGAGKSTIGRRLAQALDLPLFDTDVAVEEEAGRTIAEIFVQEGEPAFRALEEEIVRKAIESHEGIVSLGGGSILSERTRELLKGHTVIYLEISVAEGLKRTGTNTARPLLAGGDPRQKYTELMRKRRPLYRQVASIRIRTDGRSPARVVQQLVAKLAE
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_RUMCH
Sequence: MLLDDRKLKILQAIIDDYIYSAEPVGSRTIAKKHELGLSSATIRNEMADLEEMGLLEQPYTSAGRIPSDRGYRLYVDQLMKIDELNECEIEKIRSDMNIRINELSQLIRSASAVMAKITKYTSMAVSPHMKKSVLKSVQVVPIESGKALVIIVTDANIVRNNLIRIPESVTPAFLIQISNMLNEQLKGFTLEMLKSDILNEKFEKLTALPFRLIKPILDGIEELIITIDNPEVYLEGATNILNFPEFKEVDKAKEFLNILDEKKLVSDLLTNSVNDNNEIIIHIGNENAMEGIKDCSLVTASYSVGNHVIGTIGIIGPTRMEYSRVVSSMNYIRNKINQEILKLLDNG
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.