PharMolix/UniProtQA huggingface dataset:
Protein: SCYL2_HUMAN
Sequence: MESMLNKLKSTVTKVTADVTSAVMGNPVTREFDVGRHIASGGNGLAWKIFNGTKKSTKQEVAVFVFDKKLIDKYQKFEKDQIIDSLKRGVQQLTRLRHPRLLTVQHPLEESRDCLAFCTEPVFASLANVLGNWENLPSPISPDIKDYKLYDVETKYGLLQVSEGLSFLHSSVKMVHGNITPENIILNKSGAWKIMGFDFCVSSTNPSEQEPKFPCKEWDPNLPSLCLPNPEYLAPEYILSVSCETASDMYSLGTVMYAVFNKGKPIFEVNKQDIYKSFSRQLDQLSRLGSSSLTNIPEEVREHVKLLLNVTPTVRPDADQMTKIPFFDDVGAVTLQYFDTLFQRDNLQKSQFFKGLPKVLPKLPKRVIVQRILPCLTSEFVNPDMVPFVLPNVLLIAEECTKEEYVKLILPELGPVFKQQEPIQILLIFLQKMDLLLTKTPPDEIKNSVLPMVYRALEAPSIQIQELCLNIIPTFANLIDYPSMKNALIPRIKNACLQTSSLAVRVNSLVCLGKILEYLDKWFVLDDILPFLQQIPSKEPAVLMGILGIYKCTFTHKKLGITKEQLAGKVLPHLIPLSIENNLNLNQFNSFISVIKEMLNRLESEHKTKLEQLHIMQEQQKSLDIGNQMNVSEEMKVTNIGNQQIDKVFNNIGADLLTGSESENKEDGLQNKHKRASLTLEEKQKLAKEQEQAQKLKSQQPLKPQVHTPVATVKQTKDLTDTLMDNMSSLTSLSVSTPKSSASSTFTSVPSMGIGMMFSTPTDNTKRNLTNGLNANMGFQTSGFNMPVNTNQNFYSSPSTVGVTKMTLGTPPTLPNFNALSVPPAGAKQTQQRPTDMSALNNLFGPQKPKVSMNQLSQQKPNQWLNQFVPPQGSPTMGSSVMGTQMNVIGQSAFGMQGNPFFNPQNFAQPPTTMTNSSSASNDLKDLFG
What is the function of this protein?
Component of the AP2-containing clathrin coat that may regulate clathrin-dependent trafficking at plasma membrane, TGN and endosomal system (Probable).  A possible serine/threonine-protein kinase toward the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine has not been confirmed (PubMed:15809293, PubMed:16914521).  By regulating the expression of excitatory receptors at synapses, plays an essential role in neuronal function and signaling and in brain development (By similarity).
What are the official names of this protein?
SCY1-like protein 2, Coated vesicle-associated kinase of 104 kDa.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus, trans-Golgi network membrane. Endosome membrane. Note=Colocalizes to the trans-Golgi network (TGN) and to endosomal membranes with clathrin, transferrin and plasma membrane adapter AP1 and AP3 complexes.
Protein: TBP_HALMA
Sequence: MVDPKESIDIENVVASTGIGQELDLESVAMDLEGADYDPEQFPGLVYRTQDPKSAALIFRSGKIVCTGAKSTDDVHQSLRIVFDKLRDLNIQVDDDPEIVVQNIVSSADLGSSLNLNAIAIGLGLENIEYEPEQFPGLVYRLDEPDVVALLFGSGKLVVTGGKRKEDAEEAVDTIVERLSDLGLLD
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: TSAC_HYDCU
Sequence: MNCPLLTIKAAAKLITEGGVLAYPTEAVYGLGCDPLNKDAFQQLLRLKQRPLEKGVILIASSIAQIEPFVKLHNQAWTEKVLASWQVLNQPVTWVLPATDNVPEWITGGRNTVAVRVTQHPDVMALCNQLNFPIVSTSANLSGEDPVTTMEACCKAFPALAIMQGNLMGISAPSQIWEAQTQKRLR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_SALPB
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNATDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RS9A_YEAST
Sequence: MPRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAADEADEADEE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  uS4 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (PubMed:15590835).
What are the official names of this protein?
40S ribosomal protein S9-A, RP21, S13, Small ribosomal subunit protein uS4-A, YP28, YS11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: LYSC_TRAVT
Sequence: MKALTILGLVLLSVTVQGKIFERCELARTLKKLGLDGYKGVSLANWVCLAKWESGYNTEATNYNPGDESTDYGIFQINSRYWCNNGKTPGAVDACHISCSALLQNNIADAVACAKRVVSDPQGIRAWVAWRNHCQNKDVSQYVKGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.  Also plays a role in digestion in this species.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR11_ORYNI
Sequence: MTKAIPKIGSRRKVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DBH_BUCBP
Sequence: MNKSELINIISKKSNLSKIQIKNILEITLTAIIQSLKDGNSVQLVGFGTFKVNNRAARIGRNPQTGQTIHISATKTPVFISGKTFKTAIKTI
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PSOB_ASPFU
Sequence: MATIHKLFKSPFFDFEFLRLLAMAPYEGAEIGEVLEAAAKIKDQDPESWYSTLLETGGKAEAIAKQAEASGDRVGARRAYLRSSNYLRAAQFMLNEGPIGHDERVLPTLERAIANFRKGVQYRDGKTIFLEIPYEGGKTLPGYLYLPPAARRIPGRKIPILLNSGGGDSTQEEIYFVNPAYGPDLGYAVLTFEGPGQGIVLRRDKLPMRPDWESVTGPVLDHLFDLATRHPELELDLDHIAVTGASMGGYFALRAAADPRIKACVSVDGFYSLSSFVGGRMPGPLFNGFMSGWLSDWMFNGILGVLKKLAFQARWEFNHLRWATGSTTDADVMRSFGAYTLQKADGTEYLADVKCPTLVTGAGASFYFDPATTTDKIYDCLTSLQDGVDKEKWIATDVAYGGLQAKIGAFGYSAQKTFEWLDQRFGIQREPLAASSRLEDLVSRL
What is the function of this protein?
Alpha/beta hydrolase; part of the gene cluster that mediates the biosynthesis of pseurotin A, a competitive inhibitor of chitin synthase and an inducer of nerve-cell proliferation (PubMed:24082142, PubMed:24939566).  The PKS-NRPS hybrid synthetase psoA is responsible for the biosynthesis of azaspirene, one of the first intermediates having the 1-oxa-7-azaspiro[4,4]-non-2-ene-4,6-dione core of pseurotin, via condensation of one acetyl-CoA, 4 malonyl-CoA, and a L-phenylalanine molecule (PubMed:24082142, PubMed:24939566).  The dual-functional monooxygenase/methyltransferase psoF seems to be involved in the addition of the C3 methyl group onto the pseurotin scaffold (PubMed:24939566).  Azaspirene is then converted to synerazol through 4 steps including oxidation of C17 by the cytochrome P450 monooxygenase psoD, O-methylation of the hydroxy group of C8 by the methyltransferase psoC, and the trans-to-cis isomerization of the C13 olefin by the glutathione S-transferase psoE (PubMed:24939566).  The fourth step of synerazol production is performed by the dual-functional monooxygenase/methyltransferase psoF which seems to catalyze the epoxidation of the intermediate deepoxy-synerazol (PubMed:24939566).  Synerazol can be attacked by a water molecule nonenzymatically at two different positions to yield two diol products, pseurotin A and pseurotin D (PubMed:24939566).
What are the official names of this protein?
Alpha/beta hydrolase psoB, Pseurotin biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. FUS2 hydrolase family.
Protein: RL22_XANOP
Sequence: MEAKAILRTARISPQKARLVADQVRGLSAERAVNLLKFSDKKAAHLIKKVVESAIANAENNQGADVDELKVKTIMVDEGPSLKRFMARAKGRGTRILKRTSHITVIVGAAK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TUSA_SHEPC
Sequence: MNDAFSNAQHKLDALGLRCPEPVMMVRKTVRQMAAGETLLIIADDPATTRDIPSFCEFMDHTLIASETAQTPYQYLIKKGL
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLP9A_ARATH
Sequence: MLIFTIPQFFFAAWVMVVSLQMQGYISCIEKERKGLLELKAYVNKEYSYDWSNDTKSDCCRWERVECDRTSGRVIGLFLNQTFSDPILINLSLFHPFEELRTLNLYDFGCTGWFDDIHGYKSLGKLKKLEILDMGNNEVNNSVLPFLNAASSLRTLILHGNNMEGTFPMKELKDLSNLELLDLSGNLLNGPVPGLAVLHKLHALDLSDNTFSGSLGREGLCQLKNLQELDLSQNEFTGPFPQCFSSLTQLQVLDMSSNQFNGTLPSVISNLDSLEYLSLSDNKFEGFFSFDLIANLSKLKVFKLSSKSSLLHIESEISLQLKFRLSVIDLKYCNLEAVPSFLQQQKDLRLINLSNNKLTGISPSWFLENYPKLRVLLLWNNSFTIFHLPRLLVHSLHVLDLSVNKFDEWLPNNIGHVLPNISHLNLSNNGFQGNLPSSFSEMKKIFFLDLSHNNLSGSLPKKFCIGCSSLSILKLSYNRFSGKIFPQPMKLESLRVLIADNNQFTEITDVLIHSKGLVFLELSNNSLQGVIPSWFGGFYFLYLSVSDNLLNGTIPSTLFNVSFQLLDLSRNKFSGNLPSHFSFRHMGLLYLHDNEFSGPVPSTLLENVMLLDLRNNKLSGTIPRFVSNRYFLYLLLRGNALTGHIPTSLCELKSIRVLDLANNRLNGSIPPCLNNVSFGRSLDYEIDPDFGSSYGMVRADQELEESYSRSLVLPLEFELDYSGYLDFTVEFASKRRYDSYMGESFKFMFGLDFSSNELIGEIPRELGDFQRIRALNLSHNSLSGLVPESFSNLTDIESIDLSFNVLHGPIPHDLTKLDYIVVFNVSYNNLSGLIPSQGKFLSLDVTNYIGNPFLCGTTINKSCDDNTSGFKEIDSHSGDDETAIDMETFYWSLFATYGITWMAFIVFLCFDSPWRQAWFRLVNVFVSFLKCV
What are the official names of this protein?
Receptor-like protein 9a, AtRLP9a, Receptor like protein 9, AtRLP9.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: I1B6_CONAL
Sequence: GDWGTCSWPGQECEHDSDCCGSFCCVGRRCLHIYFPCNLSRS
What are the official names of this protein?
Conotoxin Au11.6.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FUT5_ARATH
Sequence: MYQKFQISGKIVKTLGLKMKVLIAVSFGSLLFILSYSNNFNNKLLDATTKVDIKETEKPVDKLIGGLLTADFDEGSCLSRYHKYFLYRKPSPYKPSEYLVSKLRSYEMLHKRCGPDTEYYKEAIEKLSRDDASESNGECRYIVWVAGYGLGNRLLTLASVFLYALLTERIILVDNRKDVSDLLCEPFPGTSWLLPLDFPMLNYTYAWGYNKEYPRCYGTMSEKHSINSTSIPPHLYMHNLHDSRDSDKLFVCQKDQSLIDKVPWLIVQANVYFVPSLWFNPTFQTELVKLFPQKETVFHHLARYLFHPTNEVWDMVTDYYHAHLSKADERLGIQIRVFGKPDGRFKHVIDQVISCTQREKLLPEFATPEESKVNISKTPKLKSVLVASLYPEFSGNLTNMFSKRPSSTGEIVEVYQPSGERVQQTDKKSHDQKALAEMYLLSLTDNIVTSARSTFGYVSYSLGGLKPWLLYQPTNFTTPNPPCVRSKSMEPCYLTPPSHGCEADWGTNSGKILPFVRHCEDLIYGGLKLYDEF
What is the function of this protein?
May be involved in cell wall biosynthesis.  May act as a fucosyltransferase.
What are the official names of this protein?
Probable fucosyltransferase 5, AtFUT5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 37 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: LPXZ_CHLTE
Sequence: MLIHQRTLQNEISLTGIGLHTGHECTITFKPAPVNTGYIFVRTDINDCPEIPALIDHVVDVLRGTTIGIGDVKVHTTEHVLAALYGLQIDNCRIELSGPEPPVLDGSSNPFAEALLSAGIAEQDEPKNYLVIDETIEFHNPEKSVDIVALPLDGFRMTVMVDYKNPALGSQHSGLFDLDKEFLREFSPCRTFCFLSEVEAMANQGIIKGADIDNAIVIVDKQLDETEVQTLADKVGVDASHLVLGQNGILNNRELRFSNEPARHKLLDLLGDLALLGMPVKAQILAXRPGHASNVEFVKQLKKYADRNKLARQYQHEKKAGVIFDINAIQNILPHRYPFLLIDKIVEFKLDEKIVSIKNVTMNEPFFQGHFPGNPIMPGVLIIEAMAQTGGIMMLNGKENIKESVVFFMGIDKARFRKPVLPGDTLVIEAVMTNMRRTVCQFDAKAYVRGELVCEASLMATVMEKKN
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
Bifunctional enzyme LpxC/FabZ.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thioester dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTD2_SCHPO
Sequence: MSAKVVLKDFLSQAPIDKLKATLSGHLPVSCITMDAKITSLQPGYHFLFFSLASPESNLNSDGYESLYSPKPNNPFSFKRRIWLHGVLRFHRPLHLFQTSECHELIQEESVKSPSITKEVEACLPKSSFLTKPTSEKQTKHVYIRRKIYDSQHQLCIEEDRTLAYLNRQELAIPKTLRSKSIPQHSWVFTPTPIMVFRYSALMFNAHMIHWNATYATKSENYPNLVLPGPLLVTSMLEYFRSVYPQMSKNMKRFEFRLLSPAFVNQPLRICISETGNLWIDRFTTDLDPPSLIARGRVYT
What is the function of this protein?
Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis.  Required for respiratory growth and for normal mitochondrial morphology (By similarity).
What are the official names of this protein?
Hydroxyacyl-thioester dehydratase type 2, mitochondrial, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase.
What is the protein family that this protein belongs to?
Belongs to the HTD2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PFKA1_CLOPE
Sequence: MKKIAVLTSGGDAPGMNAALRAVTRMALHHGLEVMGVQRGYAGLINGELFKMDRKSVSEIINRGGTILRTARCLEFKQEEVREKAAQILKAYGVEALVVIGGDGSFMGAKLLSKLGVKTVGLPGTIDNDLSYTDYTIGFDTALNTVVDAINKLRDTSTSHERVSIVEVMGRNCGDLALYAGIAGGAEAIIVPEMPFDKDELIKTILEGRTNGKTHSIIVVAEGVGGSAELAKEIESVTGIETRATILGHIQRGGSPTADDIVLASRMGAKAVEVLLEGKTSKVIGIKENRIFDMDIDEALDIERSFDESLYEMANAINK
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase 1, ATP-PFK 1, Phosphofructokinase 1, Phosphohexokinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_LEPCP
Sequence: MQPDRDTLLAGAQALGCPLSDTQADALLAYLGLLQRWNQVYNLTAIRDPKQMLVQHLLDSLAVIAPLNRVAGSAPLRLLDVGSGGGLPGVVIAVLRPDCQITCVDTVAKKATFIRQVTAELRLPQLVARHARVEQLTDGPYSVITARAFASLADLVKLTRPLLAPGGCWMAMKGQHPQAEIDALDADINVFHVEQLSVPGLDAERRLVWMRPRSVASS
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLTC_LACGA
Sequence: MDTKQAVLDILNELTGEDLSDQMDENIFENGLLDSMATVQMLLELQDKCGVTAPVSEFHREDWDTPNKIIAKVESLRNE
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_VIBPA
Sequence: MDVIQPCIKIQVHTKYIEEQSNPELQRFVFAYVITIKNLSQQTVQLISRRWLITDSNGKQMTVEGEGVVGQQPFIPSNDEYTYSSGTALETPVGVMQGHYKMLDEKGQEFITEIEPFRLAIPNVLN
What are the official names of this protein?
Protein ApaG.
Protein: CYB_SCAPL
Sequence: LLGLCLITQILTGLFLAMHYTADISTAFSSVAHICRDVNYGWLIRNVHANGASFFFICLYLHVARGMYYGSYLQKETWNIGVVLLLLTMMTAFVGYVL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MUTL_PERMH
Sequence: MRRIKPLSEDLIRKIAAGEVVERPANVLKELIENAIDAGSDRIDIFIEKGGKRLIQVVDNGEGIHPDDMLDCVKRYTTSKISSEDDLYSISSYGFRGEALYSISSVSKFSIVSRPEDLSVGKELYIEGGVFRSFTETGAPVGTKVRVKDIFFNTPVRKKFLKSERTEFVHCLKTFINYAVVNTDIHFRLYHNGRELMNLPPSDLKKRITYIYPELSGRLLELDYTDETGRIYGYISTDERFKKEGIVYVNKRPVKNRELRKIIKSLISEKFYVLFIELPPYFVDHNVHPAKIEVKFKNDTAVKNLVREGLKALETPFKKGVTFDYTVSQRKGSYGKEKVFDLLGQVENTFIVVYYDGDIYLIDQHVVHERINYEILMEDLREDGFIKRKILNRNITHSISELEKALIEDKKGTLERSGFSFDIDGYNLVIKEIPVFVSEDQALDIFFRILMDEDAETVDYVIGEIACKLSVKSGDILSDEKAKLILKRWFETDSPNLCPHGRPVYYKVSIDDVKKAIGRG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: UREH_HELPS
Sequence: MNTYAQESKLRLKTKIGADGRCVIEDNFFTPPFKLMAPFYPKDDLAEIMLLAVSPGMMRGDAQDMQLNIGPNCKLRITSQSFEKIHNTEDGFASREMHIVVGENAFLDFAPFPLIPFENAHFKGNTTISLRSSSQLLYSEIIVAGRVARNELFQFNRLHTKISILQDEKPIYYDNTILDPKTTDLNNMCMFDGYTHYLNLVLVNCPIELSGAREWIEESEGVDGAVSEIASSHLCVKALAKGSEPLLHLREKIARSITQTITQKI
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreH.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_PROMS
Sequence: MRVTTSFPLGTLRDTPSEAEIISHQLLLKAGYIRRVNSGIYAYMPLMLRVIEKISAIIEKELNSIGCTKLLLPQLHPADLWKKSERWEGYTAGEGIMFNLKDRQGKEFGLAPTHEEVITSIASETINSYKQLPQCFYQIQTKFRDEIRPRFGLMRSREFIMKDGYSFHSSQNDLASFYEKVSNAYENIFKSCGLQTVGVEADSGAIGGASSKEFMVTADAGEDSILFTQSGSYAANIEKAVSLPSQPIPLKDNIPEWLETPHQKTILEVCDNNNLDPSQIIKVVIFLAQFEGEFNVPILACIRGDQHINEVKLFNLINKLNHFNLLNLKKIEDKKTIEKNLVDLPLGFIGPDLDNNTIKAISNWEKQWTRIIDHSASDLSKFISGGNKVNFHKVFQEFSFDSKDYLIGDIRNAKKGDKISVYDDEELKEKKGIEIGHIFQLGQKYSEKLNAKFSDKDGQLKNLWMGCYGIGVTRIAQAAIEQNHDQKGICWPIHISPFEVIIIPTNLKDPIQSDLTEQIYSNFLINKIDVLLDDRNDRAGVKFKDAELIGIPFQIIIGRDSINKEVELLCRTNNTKLKISTDKLLETFISESEIMYNKKS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ION3_CARAU
Sequence: MSYTKKTSYSVKSSSSGSVPRSFSSMSYSGPSVTRQSYSVRTSYGGANRGMGAGMGGGGFISSSSAYGLGMGMGSGVVAPIQAVTFNKSLLAPLNLEIDPNIQVVRTQEKEQMKSLNNRFASFIDKVRFLEQQNKMLETKWSLLQNQTATRSNIDAMFEAYINNLRRQLDSLGNDKMKLEADLHNMQGLVEDFKNKYEDEINKRTECENDFVLIKKDVDEAYMNKVELEAKLESLSDEINFLRQIFEEEIRELQSQIKDTSVVVEMDNSRNLDMDAIVAEVRAQYEDIANRSRAEAEMWYKSKYEEMQTSATKYGDDLRSTKTEIADLNRMIQRLQSEIDAVKGQRSNLENQIAEAEERGELAVRDAKARIKDLEDALQRAKQDMARQIREYQELMNVKLALDIEIATYRKLLEGEEDRLLSGIKSVNISKQSTSYGSYPMESASSGYSNYSSGYGGGYGGGYSSGGGYSSGGGYSSGGGYSSGSGYSETVSQTKKSVVIKMIETKDGRVVSESSEVVQD
What is the function of this protein?
One of the non-neuronal predominant intermediate filament proteins of the visual pathway.
What are the official names of this protein?
Intermediate filament protein ON3.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RS20_META1
Sequence: MANIKSKQKAILYNQKANAYNSAVKSTVKTAIKKAKLAADQQDAKLSDFVSKAHHEIDKAVSKGVLHKNNGSRKASRLDAYVQSKQQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.