PharMolix/UniProtQA huggingface dataset:
Protein: CH10_STRU0
Sequence: MLKPLGDRVVVRFEEEKEQTVGGFVLAGNHKESTRKATVVAVSETGMRTITGEVVPPSVTVGQMVLVEDGQVLEVTHEDEKLAIIREADIIAILG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_ALCBS
Sequence: MAVSKEDILGAIADMSVMDLVELIEAMEEKFGVTAAAAVAAAPAAAGGDAAAAEEQTEFDVVLSSFGDKKVGVIKAVREVTGLGLKEAKELVESAPAPVKEGATKDEAEEIKKKIEEAGGTAELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PSAA_SYNP6
Sequence: MTISPPEREAKVKATVDKNPVPTSFEKWGKPGHFDRTLAKGPKTTTWIWNLHANAHDFDSHTSDLEDISRKIFSAHFGHLAVIFIWLSGAYFHGARFSNFSGWLADPTHVKPSAQVVWPIFGQEILNGDVGGGFHGIQITSGLFQLWRASGYTNEFQLYVTAIGALVMAGLMLFAGWFHYHKAAPKLEWFQNVESMLNHHLAGLLGLGSLSWAGHQIHVSLPVNKLLDAIDAGEPLVLNGKTIASAADIPLPHEFLDVSLISQLFPGFEAGVKAFFTLNWSAYADFLTFKGGLNPVTGGLWLTDTAHHHLAIAVLFIVAGHMYRTNWGIGHSLKEILEAHKGPFTGQGHKGLYEILTTSWHAQLSINLAILGSISIIVAHHMYAMPPYPYLATDYPTMLSLFTHHIWIGGFLIVGAGAHAAIFMVRDYDPAKNVDNLLDRVLRHRDAIISHLNWVCIWLGFHSFGLYIHNDTMRALGRPQDMFSDSAIQLQPIFAQWIQNIHALAPGNTAPNALASVSQVFGGDVVAVGGKVAAAPIVLGTADFMVHHIHAFTIHVTALILLKGVLYARSSRLVPDKANLGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNSLSIVIFHYSWKMQSDVWGSVLPDGSVAHIANGNFAQSALTINGWLRDFLWAQASQVITSYGSSTSAYGLLFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIIQGRAVGVAHYLLGGIVTTWSFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SNCAP_HUMAN
Sequence: MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDTQNEDRSVSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGPPGKSSEPSTSLGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLSGKACSTGSSESSSSNMAPFCVLSPVKSPHLRKASAVIHDQHKLSTEETEISPPLVKCGSAYEPENQSKDFLNKTFSDPHGRKVEKTTPDCQLRAFHLQSSAAESKPEEQVSGLNRTSSQGPEERSEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSLMGEDCLNERNTEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSASSRARPKAKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQASSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRPRPQPIVESVESMDSAESLHLMIKKHTLASGGRRFPFSIKASKSLDGHSPSPTSESSEPDLESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRVTFEEPVVQMEQPSLELNGEKDKDKGRTLQRTSTSNESGDQLKRPFGAFRSIMETLSGNQNNNNNYQAANQLKTSTLPLTSLGRKTDAKGNPASSASKGKNKAA
What is the function of this protein?
Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins.  Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH.  Isoform 2 modulates SNCA monoubiquitination by SIAH1.
What are the official names of this protein?
Synphilin-1, Sph1, Alpha-synuclein-interacting protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Detected in cytoplasmic inclusion bodies, together with SNCA.
Protein: METN1_STAAB
Sequence: MIEFRQVSKSFHKKKQTIDALKDVSFTVNRNDIFGVIGYSGAGKSTLVRLVNHLEAASNGQVIVDAHDITNYSDKMMRDIKKDIGMIFQHFNLLNSATVFKNVAMPLILSKKSKTEIKQRVTEMLEFVGLSDKKDQFPDELSGGQKQRVAIARALVTNPKILLCDEATSALDPSTTASILTLLKNVNQTFGITIMMITHEMRVIKDICNRVAVMEKGQVVETGTVKEVFSHPKTTIAQNFVSTVIQTEPSTSLIRRLNDEQVGDFKDYKIFVEETQVTQPIINDLIQICGREVKILFSSMSEIQGNTVCYMWLRFNMDQQFDDTAINQYFKEKNIQFEEVH
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ARGI1_BOVIN
Sequence: MSSKPQSIGVIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKELECDVKDYGDLSFADNLDDSPFQIVKNPRCVGKASEKLADVVAEVKKTGRISLVLGGDHSLAIGSISGHARVHPDLCVIWVDAHTDINTPLTTKTGNLHGQPVSFLLKELKEKMPEVPGFYWVAPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVQGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTTVAITMACFGVAREGNHKPIDYLSPPK
What are the official names of this protein?
Arginase-1, Liver-type arginase, Type I arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSA_STAAM
Sequence: MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVADTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKKIDEQIEKMQKQYGGKDKFEKALQQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEGLDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEKALFKLKDGEVSEVVKSSFGYHIIKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAYKDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NCAP_CVCAK
Sequence: MANQGQRVQWGVDITKKRGLSNSRGRKNNTIPLSFFNPITLQQGSKFWNLCPRDFVPKGIGNKDQQIGYWNRQSRYRMVKGQRKELPERWFFYYLGTGPHADAKFKDRIDGVVWVAKDGAMNKPTTLGNRGANNESKALKFDGKVPGEFQLEVNQSRDNSRSPSQSRSQSRNRSQSRGRQQSNNKKDDSVEQAVLAALKKLGVDTEKQQQRSRSKSKERSNSKTRDTTPKNENKHTWKRTAGKGDVTKFYGARSSSANFGDSDLVANGNGAKHYPQLAECVPSVSSILFGSYWTAKEDGDQIEVTFTHKYHLPKDDPKTGQFLQQINAYARPSEVAKEQRQRKARSKSAERVEQEVVPDALTENYTDVFDDTQVEIIDEVTN
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the alphacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: PSRP_AERHH
Sequence: MHTVFYVSDGTAITAEVFGHAVLSQFPLAFEQITIPFVETLEKARQVRMRIDEQFRQTGVRPILFHTIVDHQVREEVLKAQASSHDFLNTFVSPLEHELGVKAEPRLHRTHGMENRKLYDDRIEAVNFALANDDGITTKEYDEADIILIGVSRCGKTPTSLYLALQFGIRAANYPFIEQDMGVLDLPAALKANRHKLFGLTIAPQRLHEIRNQRRANSRYSSLEQCEQELACVERLFRQEAIRFLDTSSHSVEEISAKILEATGLRRQLY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: HIS2_META3
Sequence: MDILKEEFEIIKQRIKDKPEGSYVAYLTTADKKTPINKICEKVGEEATETILAAKDQDKQELIYESADLIFHILVLLANNGIEYEELMEEFERRRK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_METPB
Sequence: MKFRPLHDRVVVRRIESEEKTKGGIIIPDTAKEKPQEGEIVAVGPGARDEQGRVNALDVKVGDRVLFGKWSGTEVKIDGQDLLIMKESDIMGVVAA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_ACIBC
Sequence: MINTSPLLNYVSSHHDIKAINQWRTDVEKQLQDSYENGQSIREIIKARSDLVDEALVFLWKHAELDQSKLGLFAVGGYGRREMLPYSDVDIMILSEDEISEENEKRISTFISSLWDVGNFKPGISVRTIQSCVEQAATDLTVATTLIEARLITGNTQLAKWPRRIVSQTWTDKTFYDAKMAEQAKRYHQHNNTESNLEPDIKNAPGGIRDINQIGWIAKRHFRVNRIYDLVHLGFISEFELAVLEEAESFLWEIRHHLHRLAKRDENRLLFDHQREIAAKFGYVRQEGQPVNYGVEQFMKRYYRTAQQVSTLNEMLLAYFSESVITPRLPNYERKIEVVNDHFKIVDNKLAVQHHKIFAEHPSAILELFYILANRPDIEGIRARTLRLLILAAKRINQSYRDNPEHQALFMSIIRSPYRLYDTLVAMKRYGVLGNYIPAFAQIMGLMQYDLFHIYTVDAHTLLLLRNLNRFREPEFAKEFPVVSSVFQRLARQDIVFIAALFHDIAKGRGGDHSELGAEDAIEFGRAHGFTERECKLIAWLIQNHLLMSLTAQKKDISDPDVVKDFAEKLGDMEHLDYLYTLTVADINATNPKLWNTWRASLMRQLYTHARDVIRTGLGRPVDYQMLIEDTKFAASELLVNNFALADVEKVWQELGDEYFIKESADEIAWHTQAILKHGDNPEPLVLLRAHRKAAQDAVQIFIYTRDQPNLFATTVAVLDRMNLDVQDAKIITASTAFSLDTYVVLDRFGTLLTDPEREETVKNALVKALSQPDQYPGLMQRRIPRQLRHFDIENTVDVTLNEALQQNMVEISTLDHPGLLARVGGLFMMQGLDIHSARIATLGERAEDIFFVTKKDGKPLNNEEVKLFSEKLKAALDEASNQICQH
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: ATI1B_ALYOB
Sequence: GLKEIFKAGLGSLVKGIAAHVAN
What is the function of this protein?
Antibacterial peptide with amphipathic alpha-helical structure.  Shows selective growth inhibitory activity against the Gram-negative bacteria E. coli (MIC=25 uM).  Has a weak hemolytic activity against human erythrocytes (LC(50)=200 uM).  Is not active against S. aureus (MIC=200 uM).
What are the official names of this protein?
Alyteserin-1b.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Alyteserin-1 subfamily.
Protein: LEG_ELEEL
Sequence: SMNGVVDERMSFKAGQNLTVKGVPSIDSTNFAINVGNSAEDLALHINPRFDAHGDQQAVVVNSFQGGNWGTEQREGGFPFKQGEDFKIQITFNSEEFRIILPDGSEIHFPNNRYMHFEGEARIYSIEIK
What is the function of this protein?
This protein binds beta-galactoside.  Its physiological function is not yet known.
What are the official names of this protein?
Beta-galactoside-binding lectin, 14 kDa lectin, Electrolectin.
Protein: Y1909_AQUAE
Sequence: MLRLWEELNRVENLFLELLDDPKKKDVLLYLICYCQLVRRDGEYEVELPKLINCAEKPYKYISGNWQDVLLELGVLYLKDKKGKVYTGKEILLVKNPEGFKVGILPDYREDFYKFYTKLLKYWSVLNSRRTLGSNTTPDYYTPLLVHTFNEKLFKEAQYFSEILAMRFPKEKNLFLSVKLVSEFYREYAKTGRVKADNLNDAINFLSDTPDVFYSVNVKKFKKDIKKFLENLNKGEFYYITIEFASENRGKKRSILSKLWNFIKSLGGKRWNSRSSGMDYYSFIEHLLKKHRRQMMRSLESSTPRLQGT
What are the official names of this protein?
Uncharacterized protein aq_1909.
Protein: TRPB_BUCDN
Sequence: MTLLNPYFGKFGGMYVPQILMPALLELEKNFVEAQKDINFHKTFFNLLKNYAGRPTPLTLCNNLTKGTKTRIYLKREDLLHGGAHKTNQVLGQAILAIRMKKNEIIAETGAGQHGVATAIACALLNLKCRIYMGIKDIKRQHPNVFRMKLMGAEVIPVKNGSGTLKDACNEALRDWSNSYKNSHYMIGTAAGPHPYPTIVREFQKIIGEETKQQILEQETKLPNAIIACVGGGSNAIGIFSNFINDKEVSLIGVEPGGKGIKTGQHGAPLKHGRTGIFFGMKSHLMQDQEGQIQESWSISAGLDFPSVGPEHAWLNSINRAQYVSITDQEALDTFQLLCKKEGIIPALESSHALAYALKLMNLSPKKEQIFVVNLSGRGDKDIFTVHDILKKTGKRI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: MPAA5_AMBEL
Sequence: LVPCAWAGNVCGEKRAYCCSDPGRYCPWQVVCYESSEICSKKCGK
What are the official names of this protein?
Pollen allergen Amb a 5, Allergen Amb a V, Allergen Ra5.
Protein: CYB_SORHO
Sequence: MTNLRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLP
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LEXA_CLOBK
Sequence: MNKSRIDKQNEVYNFIKLQIKEKGYPPSVREICKAVGLSSTSSVHFHLKRLEKEGLIKRDSSKTRAIEIVDPTSKKEVINVPIVGTITAGNPILAIENIEDVFPLPIDYVKNTKDLFMLKVSGESMIEAGILDGDLAIIEKTDSANNGDIVVALIDNEATLKRFFKESSYIRLQPENKSMKPIILENCKVLGRLVGIYRKY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: NHAB_PSEP1
Sequence: MSRSLTGALAHGFLGQSPLWYKAVICLFLVLNPLLLATIGPAAAGWALVIEFIFTLGMALKCYPLMPGGLLLIEALLLQMTTPQALYEELQHNFPVILLLMFMVAGIHFMKELLLFLFSRILLGVRSKAMLSLLFCVLSAFLSAFLDALTVTAVIISAAVGFYAVYHRVASGANPREDSALDSDQQVAQLHRDDLNQFRAFLRSLLMHGAVGTALGGVCTLVGEPQNLLIGHEMGWHFADFLLKVAPVSIPVLGAGLLTCVLLEKLRLFGYGTLMPETVRQVLAAYAAEDDAARTQAQRIALWVQGLAALILIICLGLHVAEVGLIGLMVIVLITAFTGITDEHRLGRAFQDAMPFTSLLVVFFAVVAVIHQQQLFSPLISWVLTLPAEQQPGMLYLANGLLSAISDNVFVATIYITEVKQAFLNGSMSREHFETLAVAINTGTNLPSVATPNGQAAFLFLLTSAIAPLIRLSYGRMVWMALPYTVVMGGLGWWAVTYWL
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LUXS_STRPY
Sequence: MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLVQPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: COAD_BIFLD
Sequence: MTIAVCPGSYDPVTAGHLDVIERSARFFDEVHVVVAVNAAKTPMFSEATRVDVIRRALDKAGCKNVTVSSTDGLITDYCKKVGATVIIKGLRQNGDYEAELGMALVNRKLAGIETLFLPADPILEHISSSIVKDVARHGGDVTGMVPDCVVPMLADALAEERQRKD
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2493_STAAC
Sequence: MIHSKKLTLGICLVLLIILIVGYVIMTKTNGRNAQIKDTFNQTLKLYPTKNLDDFYDKEGFRDQEFKKGDKGTWIVNSEMVIEPKGKDMETRGMVLYINRNTRTTKGYYFISEMTDDSNGRPKDDEKRYPVKMEHNKIIPTKPLPNDKLKKEIENFKFFVQYGNFKDINDYKDGDISYNPNVPSYSAKYQLNNDDYNVQQLRKRYDIPTKQAPKLLLKGDGDLKGSSVGSRSLEFTFVENKEENIYFTDSVQYTPSEDTRYESN
What are the official names of this protein?
Uncharacterized protein SACOL2493.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PSB10_RAT
Sequence: MLKQAVEHRGGFSFENCQRNASLEHVLPGLRVPLARKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVDLNGPQLYSVHPHGSYSRLPFTALGSGQDAAVALLEDRFQPNMTLEAAQELLVEAITAGILGDLGSGGSVDACVITAGGAKLQRALSSPIEPVQRAGQYRFAPGTTPVQTQEVRALTLELLEETVQAMEVE
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  This subunit is involved in antigen processing to generate class I binding peptides (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-10, Low molecular mass protein 10, Macropain subunit MECl-1, Multicatalytic endopeptidase complex subunit MECl-1, Proteasome MECl-1, Proteasome subunit beta-2i.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATG21_VANPO
Sequence: MGLSRFNQDATCFVTSSEGNSVTIYNCDPFGKCFEMVDEDTQNIGDDDARGDDNSGGDDDLLVEMLFSTNLVAIVHRKQGILKSKKLKIVNIKRKTIICELSFPHPIQDVVMNRKRVCVLLNSDQIHIYDISCMKHLHTIDIWDSQVKSITGQGVDSLSNSGTSNMTSLRERSSTFSKSISPKICLSNDDRSILAFNCYSTSSKSVILNDVVIFDALNISPLNYINSVHKGNVASLAISPDGKFIATASEKGTLVRIFNTGAETESELLTPLLYEFRRGNRPCNINQLTFNSDSTLLGCVGDSDTIHIFKLDSTSRLLSMSVNSEDNSHITSEDIKALRKDPNSKQFTKLISKTIKKSIPSQALRRDFAHITIKNTKTKHILGFPKEFMNQVYVLSNDGSFFIYSLPSTSGSCVLSKQNDFK
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) vesicles formation and mitophagy.  Involved in binding of phosphatidylethanolamine to ATG8 and in recruitment of ATG8 and ATG5 to the pre-autophagosomal structure.  Protects ATG8 from ARG4-mediated cleavage (By similarity).
What are the official names of this protein?
Autophagy-related protein 21.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=Vacuolar and perivacuolar punctate structures.
Protein: ARL2_MOUSE
Sequence: MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDVDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATLLIFANKQDLPGALSCNAIQEALELDSIRSHHWRIQGCSAVTGEDLLPGIDWLLDDISSRVFTAD
What is the function of this protein?
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP).  GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit.  Regulates formation of new microtubules and centrosome integrity.  Prevents the TBCD-induced microtubule destruction.  Participates in association with TBCD, in the disassembly of the apical junction complexes.  Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly.  Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3.  Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine.  Required for normal progress through the cell cycle.
What are the official names of this protein?
ADP-ribosylation factor-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules (By similarity). The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria.
Protein: CHP2_MYCTU
Sequence: MKRVIAGAFAVWLVGWAGGFGTAIAASEPAYPWAPGPPPSPSPVGDASTAKVVYALGGARMPGIPWYEYTNQAGSQYFPNAKHDLIDYPAGAAFSWWPTMLLPPGSHQDNMTVGVAVKDGTNSLDNAIHHGTDPAAAVGLSQGSLVLDQEQARLANDPTAPAPDKLQFTTFGDPTGRHAFGASFLARIFPPGSHIPIPFIEYTMPQQVDSQYDTNHVVTAYDGFSDFPDRPDNLLAVANAAIGAAIAHTPIGFTGPGDVPPQNIRTTVNSRGATTTTYLVPVNHLPLTLPLRYLGMSDAEVDQIDSVLQPQIDAAYARNDNWFTRPVSVDPVRGLDPLTAPGSIVEGARGLLGSPAFGG
What is the function of this protein?
Involved in the final steps of polyacyltrehalose (PAT) biosynthesis.  Catalyzes the transfer of three mycolipenoyl groups onto diacyltrehalose (DAT) to form PAT.
What are the official names of this protein?
Diacyltrehalose acyltransferase Chp2.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL28_VESOH
Sequence: MAKVCMVTGKRPISGNNVSHANNKTRRRFYPNLHKHRFWVESENRFVKLKLSAKGFRIIDKKGINIVLTEIRARGKFKESSL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.