PharMolix/UniProtQA huggingface dataset:
Protein: Y1024_STRPJ
Sequence: MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLTGDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SPN23F10240.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: O162A_CONPL
Sequence: MKLTCVVIVAVLFLTACQLITAETYSRGEQKHRALSSTDKNSKLTRTCNTPTQYCTLHRHCCSLYCHKTIHACA
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like PuIIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL10_SALDC
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTQFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: TVP18_YEAS7
Sequence: MALSLGQFINVGGMVKDLKSFNFSVYGRWFGYINIILCIALGIANLFHVSGVIAFGIISIIQGLVILFIEIPFLLKICPLSDNFIEFIKRFETNGWRCLFYLAMAIIQYISIAVMATSLIVVAVGLTISSISYAVAYTKHQEFQNTNIIKNPTDDDFPHEAVVREML
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP18, TLG2 compartment vesicle protein of 18 kDa.
What is the protein family that this protein belongs to?
Belongs to the TVP18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: PROB_MARMS
Sequence: MEMREKIAKAQRVVVKIGSALLTNDGQGLDVARIGLWVAQIAELRAQGKEVVLVSSGSIAAGMKRLGFSSRPTQVNELQAAAAVGQMELVGVYESHFEKHGLCTAQILLTHDDLSNRRRYLNARSSLRTLLGFGVVPIINENDTVVTDEIRFGDNDTLGALVANLVEADLLIILTDQQGLFDKNPRDHQDATLISHISASDNRLESMASGGAGVLGSGGMLTKVRAALLAARSGADTLIASGREENVIVRVASGEMMGTWLQPEHGRVAARKQWLAGHLKSRGALILDDGAVKALRKEGTSLLAVGVKDAQGTFSRGDMVVCVDLQGGLVARGLVNYSVAETLKLLGQPSSNIGAILGYKGEPELIHRDDLVII
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFBU_ECO27
Sequence: MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQMRELDREFGELKEETCRTIIDIMEMYHALHVSWSNLHDQQSIDERRVTFLGFDAATEARYLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQIINA
What are the official names of this protein?
UPF0304 protein YfbU.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: DSC1_BOVIN
Sequence: MAVASAAPGSIFWKQLLFSLLVLILFCDACQKISLQVPSHLRAEALVGKVNLKECLQSASLILSSDPDFRILEDGSIYTTHDLVLSSGKSFSILLSDSQGQGQKEIEIILEAGGKKVPKRHMKDAVLRRTKRRWAPIPCSLMENSLGPFPQHVQQVQSDAAQNYTIFYSISGPGVDKEPFNLFFIEKDTGDIFCTRSIDREQYQEFPIYAYATTADGYAPEYPLPLVFKVEDDNDNAPYFENKLTVFTVPENCRTGTSVGKVTAIDLDEPDTLHTRLKYKILQQIPNNPRHFTVHPDTGVITTTTPLLDREKCDTYKLIMEVRDMGGQPFGLFNTGTITISLEDENDNAPYFTETSYTVEVEENRIDVEILRMAVHDHDLPNTPHSRAVYQILQGNENGTFKISTDPNTNEAVLCVVKPLNYEVNRQVVLQIGVLNEAQFAKAVNSKTTTTMCTTVVTVKVKDHDEGPECQPPVKVIQSEDCLPTGTELLGYKAVDPERGTGEGLRYKKIQDEDNWFEINEYTGDLKTVKVLDRESTFVKNNQYNVSVIAFDADGRSCTGTLVVFLEDKNDHPPQIKQEELTICRHDKDYVVLEPTDQDGPDNGPPFQFILDNSASKLWTVETRDGKTAILRGRQDLDYDYYTVPIQIKDRHGASATHILPVRVCDCTIPSECRMPSKLSREAALANVFLGKWAILAMVLGSVLLLCILFTCFCVTVKKTVKKCFPEDVAQQNLIVSNTEGPGEEVMDANIRLPTQTSNVCDTSISVGTLGGQGVKTQQSFEMVKGGYTLDANKGGGHQTLESVKGVTDTGRYTYSDWHNFTQPRLGEKVYLCGQDEEHKLCEDYVRSYSYEGKGSVAGSVGCCSDRQEEEGLDFLDHLEPKFRTLAKTCVKK
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.  May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.  Linked to the keratinization of epithelial tissues.
What are the official names of this protein?
Desmocollin-1, Desmosomal glycoprotein 2/3, DG2/DG3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: PROA_BACCZ
Sequence: MNEVLAKGKKAKEIARELVLKSTEQKNEALSAIADQLILETAYILEENKKDIEEGKAKGFSDSLLDRLMLNEQRIVDMTEGIKQLIELRDPVGDCVSAWERPNGLSIQEMRVPLGVVGMIYEARPNVTVDAATICLKTGNAVILRGSSSAIHSNKAIVAVIHRALKQTSLPQESVQLIEDTTRDSAKQLFTMNDYLDVLIPRGGKQLIDTVVREASVPVLETGAGNCHVFIDETADKQMAFDIIINAKTQRPSVCNAIETIVLHEKWAEQYGSELFSSLKKRGVELRGDQKALAMDSSIVLASEEDWGTEFLSLTLAVKLVSSIEEAIHHINTYGSMHSEAIISENEENVSKFFVSVDAAALYHNASTRFTDGYEFGFGAEIGISTQKLHVRGPMGLPALTSIKYVIRGNGQIRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_CLOBH
Sequence: MENRMVTPFDVEDDREQYSLRPTTLKEYIGQKKVKANLDIFIKAAKKRNESLDHVLFYGPPGLGKTTLANIIANEMTGNLKVTSGPAIEKAGDLAAILTSLTDYDVLFIDEIHRLNRSIEEILYPAMEDYALDIVIGKGAAAKSIRLDLPKFTLIGATTRVGLLTSPLRDRFGMLCAMEFYTDEELMEIVVRSAAILNVNICREAAFEIGKRSRGTPRIANRLLKRVRDYCDVKHDGDIDLQGAKAALDLLEVDKEGLDKIDNKILEAIIFNFKGGPVGLETLAYFIGEELDTIEDVYEPYLIQKGFIMRTPRGRVASEKAYNHFGVTKKEEKDNQVSIFNK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PDXA_PSESM
Sequence: MKPKRFALTPGEPAGIGPDLCLLLATQPQPYPLIAITSRDLLTQRAAQLGVAVSLLDVTPETLPDQPAPAGSLYVWHTPLAAPVETGVLNKANAAFVLQTLTRAGQGCLDGLFSGMITAPVHKGVINDGGIAFSGHTEFLAELTHTEQVVMMLATGDLRVALVTTHLPLREVADAITADRLERVTRILHADLVNKFGIAHPRILVCGLNPHAGESGHLGREEIDIIEPTLERLRSEGLDLRGPLPADTLFTPKYLEHCDAVLAMYHDQGLPVLKYKGFGAAVNVTLGLPIIRTSVDHGTALDLAGSANIDTGSLRVALQTAYQMAETHS
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_LACLA
Sequence: MKRDKRLEIIKEIVTNNKISTQEELQSLLLERGVEVTQATLSRDIRKLNIIKKRDKGESFYSFLTSGNSKINSDLQLYFYNFVISAKSVGALVVIRTKLGEADVLANALDDERDSRTDILGTIAGADTLLVICASEKAANILTAEIKYILLG
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_SHIB3
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: FMT_STRP3
Sequence: MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKDIKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFGQFLPTILLDSVSFAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETDNVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMFNQEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIATGQGALSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SECF_RHOM4
Sequence: MRIFENANYPFVQHRKKAYVFSGVLILLSLVSLVTRGLELGIDFKGGMEFIISGAREPGATAIREALTPVLGTEPEVKTYGAEDILIRVAAEGDINEVQRRIVETIRQRFPETQPEVVQTNIVGPRFAEDLKRGAIYSILGALLVIFVYILIRFEWRFSLGAVVALFHDVLITLGLFSLLHGWLPFSLEIDQTIIAAFLTIVGYSLNDTVVVFDRIREYMNIFKTKPFEEVVNLSINTTLSRTIITSGTTLLVVVILFIFGGEVLRGFSFALIVGIVIGTYSSIFVASPVVIELRARAAARRRLATAR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YAJC_MYCTU
Sequence: MESFVLFLPFLLIMGGFMYFASRRQRRAMQATIDLHDSLQPGERVHTTSGLEATIVAIADDTIDLEIAPGVVTTWMKLAIRDRILPDDDIDEELNEDLDKDVDDVAGERRVTNDS
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FLGH_SALEP
Sequence: MQKYALHAYPVMALMVATLTGCAWIPAKPLVQGATTAQPIPGPVPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTSFGFDTVPRYLQGLFGNSRADMEASGGNSFNGKGGANASNTFSGTLTVTVDQVLANGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNSVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: PP2B3_DROME
Sequence: MSSPAAQSNSSSSQSQSAAQQQQQQNQKANVNNTHDNKNAAATTGTAAGSGSGGAAGSAGTQQQGQGGTGTSSGPSSPTKRSTISTKERVIDSVAFPPSRKLTCADVFDARTGKPQHDVLKQHFILEGRIEESAALRIIQEGATLLRTEKTMIDIEAPVTVCGDIHGQFYDLMKLFEIGGSPATTKYLFLGDYVDRGYFSIECVLYLWSLKITYPQTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIHELEDIRRLDRFKEPPAFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYAACCDFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELMTEESEEPLSDDEAALRKEVIRNKIRAIGKMARVFSVLREESESVLQLKGLTPTGALPLGALSGGKQSLKNAMQGFSPNHKITSFAEAKGLDAVNERMPPRRDATPSPAEEGQKSLSAAAAAAANANANSING
What is the function of this protein?
Calcium-dependent, calmodulin-stimulated protein phosphatase.  This subunit may have a role in the calmodulin activation of calcineurin.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2B catalytic subunit 3, Calmodulin-dependent calcineurin A3 subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2B subfamily.
Protein: RLMN_AKKM8
Sequence: MPPLPLITAQTEEKLLAFLTEHGHTKFRTQQVLDWVWRKRVTTFDAMSNLPPALKNLLAENFRFHTPEIVEIHGSADTTRKFLTKMEDGSLVESVIIPAAAAENGEKSERVTLCVSSQVGCAFGCKFCASGLLGLKRHLTTGEIIGQILSAEAIAGKRVNNIVFMGMGEPLSNFDNLADALEIITSHRGLEIGARHITISTSGFVPGLKKLAAYPRQIRLAVSLHGATDEVRDQIMPVNKKWPLSQLIPALEEWNRGRNQMPTLEYILIRDINDSPKDASHLVRIAKRLHAKVNLIPYNTVEGLPWKRPSEERCRSFRDAVHKARIPVTMRYEKGHDINAACGQLRLRKEQEKSGKTSR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCDB_ACIFV
Sequence: MDAFVVALTSVIQDSGFVAFTWGNAVMMLVGCILLYLAIVKGFEPLLLSPIAFGCILANVPRTGFETDPGVMQLILGGIKYEIFPPLIFMGVGAMTDFGPLIANPKTLLLGAAAQIGVFVALLGAMLLGFNVKEASAIGIIGGADGPTSIYLASKMAPHLLGAIAVAAYSYMSLVPLIQPPVMKLFTSKEERKIKMAQLRTVTHFEKVVFPIVTTIFISLLLPSVCSLIGMLMLGNLFTESGCMDRLSDTAQNALMNSVTIMLATGTGLTMKAESFLTLQTIEIICLGLVAFIGGTAGGVLFGKLMSKLDGGKTNPLIGSAGVSAVPMAARVSQVVGQQADPGNFLLMHAMGPNVAGVIGTAVAAGTMLAMVGGK
What is the function of this protein?
Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
What are the official names of this protein?
Glutaconyl-CoA decarboxylase subunit beta, Carboxylyase.
What is the protein family that this protein belongs to?
Belongs to the GcdB/MmdB/OadB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYT_NEOSM
Sequence: MGRVVLTVTLLSSSFSLSSGKTVGSVISDFDAEIFSKTIAASVNGVSVDLSYRLDCDANIEPILLESEAGIEILRHDCAHVMAQAVQELYPETKLGIGPVIDDGFYYDFSTPIAFSDSDFEKIEEKIREIIQRNYRIIREEWSRDDAVSFFQKKGEKYKVELISRIPPEEKISIYKQGDFIDLCRGPHAPSTGWLKHFKLLKVSTAYWLGDAKSDSLQRIYGTAWATKDGLEAYLSFLHEAKKRDHRAIGKTMELFHLQEEAQGQVFWHENGFILYRVLENYIRNKLKTHGYREVKTPLVYNKCLWERSGHWSKFKENMFVIRSDDGEFSLKPMNCPAHIEVYKQSLKSYRDLPLRLAEFGMCHRNEASGALHGLMRVRGFVQDDAHIFCTPQQICDETIAFCGLLKEVYRDLGFTEVEVRFSDRPEVRLGNDETWDKAEIALKSAMDKAGLIYTLNPGEGAFYGPKIEFVLVDALKRKWQCGTLQVDFVLPERLDATYIDHEGKKQHPVMLHRAILGTFERFLGILIEHYDGKFPLWLAPTQVAVLTITEKVEEYAKSLLNHLSKTGIRAVSDFSNQRIDYKIRYHTTRRVPILWIIGRIEEKSNSVTVRRMGSSESEVKTVDTALGDILREFNVR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRA1_DANRE
Sequence: MFALGIYLWETIVFFSLAASQQAAARKAASPMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFQRRRRHLKEDEAGDGRFSFAAYGMGPACLQAKDGMAIKGNNNNAPTSTNPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKIIRSEDIHKQ
What is the function of this protein?
Glycine receptors are ligand-gated chloride channels.  Channel opening is triggered by extracellular glycine (PubMed:10188956, PubMed:26344198).  Plays an important role in the down-regulation of neuronal excitability.  Contributes to the generation of inhibitory postsynaptic currents.  Channel activity is potentiated by ethanol (By similarity).
What are the official names of this protein?
Glycine receptor subunit alphaZ1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Synapse. Perikaryon. Cell projection, dendrite. Cell membrane; Multi-pass membrane protein.
Protein: BRE3_CAEBR
Sequence: MNCEVKHALHCAVLVAWIVCFAYFCGVFTEPAEGTVPESPVASYGLVWTICLYLLRFTALLVLPQCLCNLCGLMMFNAFREKVQLKAAPLLSPFVCFRVVTKGNFPLLVKENIDANMKTCFEAGMENFIFEVVTDKAINLPPNPRVREVVVPTAYRTKSGAKFKARALQYCLEDDVNILQPTDWIVHLDEETLLTTNAICGILNFCEDGKHQFGQGVITYANGDIVNWLTTLSDSFRVADDMGKLRFQFKLFHKPLFGWKGSYVVTQVEAERDVSYDHGMEGSIAEDCFFSMVAMKHGYTFDFIEGEMHEKSPFTMWDFLQQRKRWLQGILLTVHSSKIAVVHKALLALSLYAWATMPLTSLQVFLCPLFPLPRCLPFDFLLSFVGALNLYMYIFGVVKSFSHKYRNSFLRLGMYLAGALMTIPFNILIENAAVLVGMFGRKDQFYIVNKDIQTV
What is the function of this protein?
Glycosyltransferase with a proposed role in glycosphingolipid biosynthesis.  Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-1, bre-2 and bre-4.  Involved in resistance to the nematotoxic C. cinerea galectin Cgl2.  Has a role in determining brood size (By similarity).
What are the official names of this protein?
Beta-1,4-mannosyltransferase bre-3, Bacillus thuringiensis toxin-resistant protein 3, Bt toxin-resistant protein 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In punctate structures throughout the cell.
Protein: OM24_PASMU
Sequence: MKNKSKLLACCLMALPISSFSIGNNNLIGVGVSAGNSIYQVKKKTAVEPFLMLDLSFGNFYMRGAAGLSELGYQHVFTPSFSTSLFLSPFDGAPIKRKDLKPGYDSIQDRKTQVAVGLGLDYDLSDLFNLPNTNISLEMKKGRRGFNSDITLTRTFMLTDKLSISPSFGLSYYSAKYTNYYFGIKKAELNKTKLKSVYHPKKAYSGHIALNSHYAITDHIGMGLSFSWETYSKAIKKSPIVKRSGEISSALNFYYMF
What are the official names of this protein?
24 kDa outer membrane protein.
What is the protein family that this protein belongs to?
Belongs to the MipA/OmpV family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RECO_STRCO
Sequence: MSLFRDDGIVLRTQKLGEADRIITLLTRGHGRVRAVARGVRRTKSKFGARLEPFSHVDVQFFSKGSELVGRGLPLCTQSETIAPYGGGIVTDYARYTAGTAMLETAERFTDHEGEPAVQQYLLLVGALRTLARGEHAPTLVLDAFLLRSLAVNGYAPTFGDCAKCGMPGPNRFFSVGSGGSVCVDCRVPGSVVPSPQALELLGALLTGDWGTADAAEPRYVREGSGLVSAYLHWHLERGLRSLRYVEK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TGT_CLOBL
Sequence: MYKLLKKSGKARRGEFTTPHGVIQTPVFMNVGTLAAIKGAVSSMDLKEIGCQVELSNTYHLHLRPGDEVVKKMGGLHKFMNWDRPILTDSGGFQVFSLSKIRKIQEEGVYFNSHIDGRKIFMGPEESMRIQSNLASTIAMAFDECVENPAPREYVEKSVERTTRWLHRCKDEMNRLNSLPDTINNKQMLFGINQGGTYEDIRIEHAKTIAKMDLDGYAIGGLAVGESHEDMYRIIDAVVPHLPEDKPIYLMGVGIPSNILEAVDRGVDFFDCVLPARNGRHAHVFTKEGKINLLNAKFELDDKPIDEGCQCPACKHYTRSYIRHLFKAKEMLAMRLCVLHNLYFYNNLMEEIRDAIDGDYFKEYKERKLKEWGGRA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RPOA_SERP5
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENAAISMRIKVQRGRGYVPASARIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: LIVF_SALTY
Sequence: MEKTMLTFEKVSAHYGKIQALHDVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRASSGRVVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLAMGGFFAERDRFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLSDTGDALLANEAVRSAYLGG
What is the function of this protein?
Component of the high-affinity branched-chain amino acid transport system.
What are the official names of this protein?
High-affinity branched-chain amino acid transport ATP-binding protein LivF, LIV-I protein F.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.