PharMolix/UniProtQA huggingface dataset:
Protein: TENB_BEAB2
Sequence: MALSEVLSMVAQLGYYEKVTGILGVVSIILLFWKLNHEPFYPALPLAGEPPQRRWFSLSNRLRYYNDCAALFDEAYHTAYAKKGKAVLVPSMGVHTAMIMPESAMNWAMSQPDDSLSIKKAFSELNQTKYSLGHSRYWEDPWQLDLVKAHLSSILQNLIPQLNEELAAAFSKHLGTDAENWKEIELEVIMRRVIAQATSRFIVGLPLCRDDGYLDLSYKVILGMVTTIWATLPFPDLIRAVTGPLASWQTRRNISRIQEHLEPLYQERISILESRDGQKSDPGPQDLFMMMLRFAQKKRPDEYANLGIMTRRVCAANFVAMHQSTVSVTNLILNIIGSDAEFNTIATLRDEITQVMRGTDAKGCWTKDTFTRMRKCDSVAREAMRLNFPLGTRGSMRTVLKDGLESPEGIKLQKGTTISWLASCAQVDADRFDNPQKFDPFRFSRASKDDDDDDDDDGRSTSSHTKDAFVTTSPQYLPFGHGKHACPGRFMVDLMFKIILAQLLTHYDLGWPEDYQGKQPPSVWQGELSEPPPGARILVKRRKV
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of tenellin-type 2-pyridones, iron-chelating compounds involved in iron stress tolerance, competition with the natural competitor fungus Metarhizium robertsii and insect hosts infection (PubMed:17216664, PubMed:19067514, PubMed:20575135, PubMed:34903054).  TenB catalyzes the selective N-hydroxylation of the 2-pyridone nitrogen of yield tellinin and 15-hydroxytellenin (15-HT), respectively (PubMed:19067514, PubMed:34903054).  The pathway begins with the assembly of the polyketide-amino acid backbone by the hybrid PKS-NRPS tenS with the help of the enoyl reductase tenC.  These enzymes catalyze the synthesis of the pyrrolidine-2-dione intermediates pretellinin A, 11-hydropretellenin A, 12-hydropretellenin A, 13-hydropretellenin A, 14-hydropretellenin A, 12-oxopretellenin A and prototellinin D.  The cytochrome P450 monooxygenase tenA then catalyzes an oxidative ring expansion of pretenellin A and 14-hydropretellenin A to form the 2-pyridone core, leading to pretenellin B and pyridovericin, respectively.  The cytochrome P450 monooxygenase tenB is then required for the selective N-hydroxylation of the 2-pyridone nitrogen of yield tellinin and 15-hydroxytellenin (15-HT), respectively.  The UDP-glucosyltransferase GT1 and the methyltransferase MT1, located outside the tenS gene cluster, contribute to the stepwise glycosylation and methylation of 15-HT to obtain the glycoside pyridovericin-N-O-(4-O-methyl-beta-D-glucopyranoside) (PMGP).  Additional related compounds such as 1-O-methyl-15-HT, (8Z)-1-O-methyl-15-HT, and O-methyltenellin A are also produced but the enzymes involved in their biosynthesis have still to be determined (PubMed:34903054).
What are the official names of this protein?
Cytochrome P450 monooxygenase tenB, Tenellin biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PRIO_MACAR
Sequence: MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWHKPSKPKTSMKHMAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYEKESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: YMF34_MARPO
Sequence: MLDQFIKHRLKLKENNKLGALTFQIVLNGIFGRTNSIYFALYEPSLHGSVCGQLIMLEVFTEMVSDDLLWCNTD
What are the official names of this protein?
Uncharacterized mitochondrial protein ymf34, ORF74.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS10_MICLC
Sequence: MAGQKIRIRLKSYDHEVIDVSARKIVDTVTRAGATVVGPVPLPTEKNVYCVIRSPHKYKDSREHFEMRTHKRLIDIIDPTPKAVDSLMRLDLPADVNIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ARLY_XANCB
Sequence: MTNLLWQKPGVAVDAKIQTFLAGDDVILDREFFLYDIAASKAHAQGLQHIGILSLEELGGLSEQLDLLAGDFRSGAFVLDAHYEDCHSAIEARLTERLGDAGRKIHTGRSRNDQILVATRLWLKDKLQRVAALSTEVAKVALDRAQAEAELPVPGYTHIQRAVVSSAGMWWAGWAEAFIDNAVRANDTFKLVDTNPLGTAAGYGVNLPLDRAHTTAELGFARLQVSPIYAQLSRGKFELAALEALGGATLDLRRIAWDLSLFTSGEFAFVALPAQYTTGSSIMPNKRNPDVIELMRATHASVAAARTEIEQLLSLPSGYHRDLQSSKGAIVHGFARGLAALELLPALLANLEWRPDKLRAAIDSGMYATDVAVEAAVAGVPFRDAYKAAAAASDSAGQGRTPEASLAARVSPGAAADLQLDVLRARWEALQ
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINAL_CHLCH
Sequence: MRAEIISVGDELLRGQRVNTNAAVIARMLSAIGVSVSHIVACSDDEADIMATCSAALGRAEVVLVTGGLGPTRDDRTKHAIQQLLGRGTVLDEASYRRIEERMAARGSAVTPLLREQAVVIEGSHVIINSRGTAAGMLLDCGEPFAHHHLILMPGVPVEMEAMMHEGVIPFLTSLSNSVICQTPLKIVGVGETAIAAMLVEIEDAMPPATMLAYLPHTAGVDLMVSSRGNSREAVEAEHQQVVDAIMERVGTLVYATREISLEEVIGEMLLRQTFTVAVAESCTGGLLASRFTDISGASTYFQQGFVVYSNEAKERALGVPHETLVAHGAVSEEVAQGMALGCLEKSGADFALATTGIAGPTGGTPEKPLGTLCYAIAVKGGGVVVCRKVVMQGTREQRKVRFSTAVLREFWMLLKEREASEE
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: DNAA_BURL3
Sequence: MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDASANTLSIAAPNRFKLDWVKSQFSGRITDLAREFWNTPIEVQFVLDPKAGMRSAPAGAAPAAPRAPLAPTGPAATVAAIAANLAANASAAPTAPADVPMTPSAAAAHHLNADDADIDLPSLPAHEAAAGRRTWRPGPGAAPAAGGEADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLYGGVGLGKTHLIHAIGNQLLLDKAGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEGVNLSEDVAFFVAKHLRSNVRELEGALRKILAYSKFHGREISIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BP4A_BRANA
Sequence: MKKSLQLSFSFLIISIILSHGMMADAQKKNCPHKIPIKGSYCAPTICLDMCKKQHGTVGSCAE
What are the official names of this protein?
Protein BP4A.
Protein: EIF3D_BOTFB
Sequence: MAPISLSDIISALPSEDSWGPSTTSETTLNGVPYAPYSKGDKLGRMADWTAEGKDGRDGRGGRQQYNRNYRDQQVYGAGTSSLFAVQLAEDESTFSVVSNTRDSTKTRFGRGGLARGRGQRGGRGDTRGGRGQFQRVGGRGGQQGYNSYDTRGGRGGARGGRKFGWKDYDKPQRNRDASVNIKPDWKMLEEIDFNRLAKLNLDTDDGEDIDSYGFLYYYDRSFDKQPVKAAERKLNVVDRASYNVTTSSDPVIQELAEKDEATIFATDSILSMLMCSPRSVYPWDIVIVRQGNKVFLDKRDNATLDMVTVNENAADAPMDASEGSKDAINQPSALAEEATYINHNFANQVMKESDSQKVEMENENPFYNSAEETDPPASKAYKYRKFDLSLNDEDPVHLVVRTELDAVSKNAISGEDQFLTVKALNEFDSKAQGSGGALDWRTKLVSQRGAVVATEMKNNSCKLARWTVQSIIAKADVMKLGFVSRANPKLNDRHVVLGVIGWKPRDFASQMNLSLSNGWGIVRTIVDMCLKREEGKYVLVKDPNKPILRLYQVPAGSFEDDGEHDVIEENVEEDD
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGBA_HELPY
Sequence: MLRLLIGLLLMSFISLQSASWQEPLRVSIEFVDLPKKIIRFPAHDLQVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATAKFRAFESMKQRHLPTPRMVARKGDLVYFRQFNNQAFLIAPNDELYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIYIVTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKLFSGSQSKNYFAYYDALVKKEKRKEVRIKKREEKIDSREIKREIKQEAIKEPKKANQGTQNAPTLEEKNYQKAERKLDAKEERRYLRDERKKAKATKKAMEFEEREKEHDERDEQETEGRRKALEMDKGDKKEERVKPKENEREIKQEAIKEPSDGNNATQQGEKQNAPKENNAQKEENKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEAGKK
What is the function of this protein?
Binds plasminogen, specifically, and in a concentration and lysine-dependent manner.  Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin.  Acquisition of plasminogen/plasmin could enable H. pylori to degrade host components.
What are the official names of this protein?
Plasminogen-binding protein PgbA.
What are the subcellular locations of this protein?
Cell surface. Note=The plasminogen- binding region is localized on the surface the bacterium.
Protein: RHMD_SALHS
Sequence: MTLPKIKHVRAWFIGGATAEKGAGGGDYHDQGGNHWIADHIATPMSKYRDYEQSRQSFGINVLGTLIVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEGKCVSDIKLIHDQMLGATMYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAVRDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGPDFWLMLDCWMSQDVNYATKLAHACAPFNLKWIEECLPPQQYEGYRELKRNAPAGMMVTSGEHHGTLQSFRTLSETGIDIMQPDVGWCGGLTTLVEIAALAKSRGQLVVPHGSSVYSHHAVITFTNTPFSEFLMTSPDCSTLRPQFDPILLDEPVPVNGRIHKSVLDKPGFGVELNRDCHLKRPYSH
What is the function of this protein?
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
What are the official names of this protein?
L-rhamnonate dehydratase, RhamD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
Protein: PSD_NOCFA
Sequence: MARRPTPPGTPETTGVGHVVDLVRASIPPLHPAGLPFVAVPLAVAVAAGKRKWVRRAGLATAAACAGFFRHPNRVPPNRPGVVVAPADGEIALVDTASPPAELGLGDQPLPRVSIFLSVLDVHVQRTPVSGVVREVRHQSGQFRSADLPEASAVNERNSMLLETQSGQQIVVVQIAGLLARRIVCDARVGDVLTIGDTYGLIRFGSRVDTYFPVGTELLVQPGQRTIGGETVLATLS
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KAIC_RIPO1
Sequence: MNEPISNSSKKTENTTQGVRKIRTMIEGFDEITHGGLPIGRTTLVSGTSGTGKTLLAVQFLYHGIKYFDYPGLFVTFEESPTDIIQNAYSFGWDLQEIVDEGKLFILDASPDPDGQEVVGSFDLSALIERIQYAINKYKAQLVSIDSVTAVFQQYDAASVVRREIFRLVARLKLLGVTSIMTTERIEEYGPIARYGVEEFVSDNVVVLRNVLEGERRRRTAEILKLRGTTHMKGEYPFTITNDGINIFPLGAMRLTQRSSNARISSGVKTLDEMCGGGFFKDSIILATGATGTGKTLLVSKFLEEGCRQGERAILFAYEESRAQLSRNAFSWGIDFEEMERKGLLKLLCSYPESAGLEDHLQIIKSEISEFKPSRIAIDSLSALARGVTNNAFRQFVIGVTGYAKQEEITGFFTNTTDQFMGAHSITESHISTITDTIIMLQYVEIRGEMSRAINVFKMRGSWHDKGIREYSINESGPTIQDSFRNYERIISGSPTRITVDEKNELSRIVRGVKDKTLDEE
What is the function of this protein?
Has a weak, temperature-independent ATPase activity; ATPase activity defines the circadian period.  The phosphorylation state of KaiC modulates its ATPase activity and effects KaiB binding.
What are the official names of this protein?
Circadian clock oscillator protein KaiC.
What is the protein family that this protein belongs to?
Belongs to the KaiC family.
Protein: PLAS1_ARATH
Sequence: MAAITSATVTIPSFTGLKLAVSSKPKTLSTISRSTSATRAPPKLALKSSLKDFGVIAVATAASIVLAGNAMAMEVLLGSDDGSLAFVPSEFTVAKGEKIVFKNNAGFPHNVVFDEDEIPSGVDASKISMDETALLNGAGETYEVTLTEPGSYGFYCAPHQGAGMVGKLTVK
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.  Seems to be a minor plastocyanin in Arabidopsis.
What are the official names of this protein?
Plastocyanin minor isoform, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
Protein: Y1222_LEVBA
Sequence: MSSLDKTMYFDFGANQPKDVHDTLVTVYQALEEKGYNPINQIVGYLLSGDPAYIPRIDDARNLIRKHERDEIIEELVRVYLNQNGSVKKS
What are the official names of this protein?
UPF0297 protein LVIS_1222.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: ADRH_PENRW
Sequence: MADSMETHKFKVIIVGGSIAGLTLAHSLSKANIDHIVIEKRAEIAPQEGAFIGVWPNGAQILDQLGLYQSLEELTAPISRMHLSFPDDYSFSSFLPKTIHERFKYPIVSLDRQKVLEILFQNYPDKSNIITNQRVSEVRLLGDSASVVTEDGSVFRGDLIVGADGVHSPLTVEYACVFGISRPIPGLRSGEHINHYGDKFCVITFHGKDGRVFWFIIQKLDRVYTYPNAPRYSPNDAADLCGKMQNVVIWQDITVGDLWKTKVVASMTALEEGIFETWSLNRIVILGDSVHKMTPNIGQGANTAIEDVAVLASLINRMIHADDLNKPSESCIETMLQEYKSLRYEPAKSTYQRSRFGARFHTRDSWLKAVVGRYVFQYVGGLIENRTIKTLAGGDTIDFLPRPDRLETGRVAQFQKSEESPQRQWTLLWVSSLALFLFFPWLGSYLHSTIS
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (Ref. 2).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase adrD via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Ref. 2).  DMAO is then converted to farnesyl-DMAO by the prenyltransferase adrG (Ref. 2).  The methyltransferase adrK catalyzes the methylation of the carboxyl group of farnesyl-DMAO to farnesyl-DMAO methyl ester which is further converted to epoxyfarnesyl-DMAO methyl ester by the FAD-dependent monooxygenase adrH (Ref. 2).  The terpene cyclase adrI then catalyzes the carbon skeletal rearrangement to generate the andrastin E, the first compound in the pathway having the andrastin scaffold, with the tetracyclic ring system (Ref. 2).  The post-cyclization tailoring enzymes adrF, adrE, adrJ, and adrA, are involved in the conversion of andrastin E into andrastin A.  The short chain dehydrogenase adrF is responsible for the oxidation of the C-3 a hydroxyl group of andrastin E to yield the corresponding ketone, andrastin D.  The ketoreductase adrE stereoselectively reduces the carbonyl moiety to reverse the stereochemistry of the C-3 position to yield andrastin F.  The acetyltransferase adrJ is the acetyltransferase that attaches the acetyl group to the C-3 hydroxyl group of andrastin F to yield andrastin C.  Finally, the cytochrome P450 monooxygenase adrA catalyzes two sequential oxidation reactions of the C-23 methyl group, to generate the corresponding alcohol andrastin B, and aldehyde andrastin A (Ref. 2).
What are the official names of this protein?
FAD-dependent monooxygenase adrH, Andrastin A biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YAAI_ECOL6
Sequence: MKSVITISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLALKLPVCRIVKRIQLSADHGDLQLSGASIYFKATRSASQTLNIPSEIKEEQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: TRPD_HELP2
Sequence: MKEILNALYHQKDLSDKEVKKLFTLIIHEKVSPVQLGAILCALKIKGESFKEISVAATTLLEHAPKPFDSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMDPTQLENCFKQTHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYDKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDITHAYELKNNEILEYDLNAKDFDLPPYDLKELQIENAQESVQACLDILENKGKDSHTMVVVANVASLLYLSHKAKDLKEGVSMTLEHLKTKAPYVHLQKIIRLSHA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RRF_BACP2
Sequence: MSKEVLNQTKEKMEKAVQAYGRELATVRAGRANASLLDKVTVDYYGAQTPLNQIASITVPEARMLIITPYDKTAIGDIEKSIQKSDLGITPTSDGNVIRIAIPALTEERRKELVKVVRKYSEEAKVAVRNVRRDANDELKKLEKNGEITEDELRSSTEDVQKLTDEYVAKIDDVMKDKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX17A_ODOMO
Sequence: MKPSGLTLAFLVVFMMAIMYNSVQAEALADADAEAFAEAGVKELFGKAWGLVKKHLPKACGLMGYVKQ
What is the function of this protein?
This homodimer composed of two cationic amphipathic alpha-helical peptides has antimicrobial activities against E. coli, S. aureus (MIC=3. 1 uM), and S. cerevisiae (MIC=3. 1 uM).  It also shows histamine-releasing activity (66. 4% at 10 uM) and a weak hemolytic activity (10. 5% at 50 uM).
What are the official names of this protein?
U-poneritoxin(01)-Om4b, U-PONTX(01)-Om4b, Pilosulin-like peptide 7, PLP7, Poneratoxin.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CAIA_SHIF8
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNSVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR3_CYAPA
Sequence: MGQKIHPIGFRLGITQKHRSCWFANPKQYPTLLQEDHLIRQYIEKNLSNAGIAQIYIQRKADRIELELRTARPGVVVGRGGRGIEVLRKGLKDLLGEQKQIRINVIEVKQIDAEAALIGEFITQQLERRVAFRRIVRKAITRAQRRGIEGIKIQISGRLNGAEIARSEWSREGRVPLQTLRAEIDYSYKRAQTIYGVLGVKVWIFKGEVIPGNPTEISE
What are the official names of this protein?
Cyanelle 30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: MCE_PYRHO
Sequence: MIWMFKRIDHVGIAVKNLEEAIKIWEGLGFKVEEIEEVPDQKVKVAVIKVGENRIELLEATTEDSPIAKFIEKRGEGIHHLAIRVENIESKLEELKQKGYKLIDEKPRVGAGGAKIAFIHPKSVTGVLLELCERKE
What are the official names of this protein?
Methylmalonyl-CoA epimerase, DL-methylmalonyl-CoA racemase.
What is the protein family that this protein belongs to?
Belongs to the methylmalonyl-CoA epimerase family.
Protein: BECN1_SCHPO
Sequence: MQYLCQRCHSLINFKDVYDDDLLKLKNLPKSRFVQASSLTEMNESGESDDQMNSSSEDYPAQRLQLYKKTISEGDYNFDNVPPPELRTPTLDSFVVLPAAKDGYEEEKNSPEEVNDLFSWKIEIYNRIFDLLSSKTKVDHPLCVECAELLTEEMSKTLRALKEEKKMYFNYDNFLSSQTVHEENTAALDSEIDELMKQINEKEEKIEEISDETDKLQKLLRELDEEKEKVYAEEQEFYNNLNQFQIKKLSLERQYDCANLEFEHNSRKLEKLQKMNVFSDIFYISHYSEPNGEGSIATINGLRLGRLPSQKVNWAEINAAWGMTVLLLDVLTEKLDFHSSSYQLKPFGSQSFIIRFDRDPNGNQVKPTKLDLFSSGELKIFMNRRFDQGMVAFLDYLHQFGDFCAAKTPSAVLPYAIENDRIGGKCIRLAFNQDENWTRALKFVLTDIKFLEAYVSSQDKQSNF
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt), autophagy, nucleophagy, and mitophagy, as a part of the autophagy-specific vps34 PI3-kinase complex I.  This complex is essential to recruit the atg8-phosphatidylinositol conjugate and the atg12-atg5 conjugate to the preautophagosomal structure.  Also involved in endosome-to-Golgi retrograde transport as part of the vps34 PI3-kinase complex II (By similarity).  Plays a role in meiosis and sporulation.
What are the official names of this protein?
Vacuolar protein sorting-associated protein atg6, Autophagy-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the beclin family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein. Cytoplasm.
Protein: SYD_CLOBK
Sequence: MGEALRGLKRTIMCGESRENNIGEKVTVMGWVQRKRNLGGLIFVDLRDRTGIMQIVFGEEINKEAFEKSDNVKSEYCIAVTGEIVKRQSPNNDMETGAVELKGEDIKILSESETPPIYIKEGLDASENIRLKYRYLDLRRPDMQKIFMIRHKTCKVVRDFLDENGFLEMETPILTKSTPEGARDYLVPSRNYKGMFYALPQSPQIFKQLLMVSGYDKYFQITKCFRDEDLRANRQPEFTQIDMELSFVEEDDVIELNERLLAKVFKEVGGIDVKLPIERMPYKIAMEKYGSDKPDLRFGMEINDLTEAVKNSEFKVFKGAIEAGGSVRAIKAENCATMGRKQIDKLQDFVKTYKAKGLAWIAYKEDEIKSPIAKFLTEEEMKAILEKMDAKAGDLILIVADKNNVVFESLGALRLHIAKELDIINKNEFRFVWITEFPLLAYNEEEGRYQAEHHPFTAIMDEDIELLDTEPGKVRAKAYDIVLNGEELGGGSIRIHDSKLQEKMFSVLGFTKEKAWERFGFLLEAFKFGPPPHGGLAYGLDRMIMFLAGTENIKDVITFPKNQNAFCPLTEAPNVVDENQLEELGIKKIEKED
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C71D8_SOYBN
Sequence: MEYSPLSIVITFFVFLLLHWLVKTYKQKSSHKLPPGPWRLPIIGNLHQLALAASLPDQALQKLVRKYGPLMHLQLGEISTLVVSSPKMAMEMMKTHDVHFVQRPQLLAPQFMVYGATDIAFAPYGDYWRQIRKICTLELLSAKRVQSFSHIRQDENKKLIQSIHSSAGSPIDLSGKLFSLLGTTVSRAAFGKENDDQDEFMSLVRKAITMTGGFEVDDMFPSLKPLHLLTRQKAKVEHVHQRADKILEDILRKHMEKRTRVKEGNGSEAEQEDLVDVLLRLKESGSLEVPMTMENIKAVIWNIFAAGTDTSASTLEWAMSEMMKNPKVKEKAQAELRQIFKGKEIIRETDLEELSYLKSVIKETLRLHPPSQLIPRECIISTNIDGYEIPIKTKVMINTWAIGRDPQYWSDADRFIPERFNDSSIDFKGNSFEYIPFGAGRRMCPGMTFGLASITLPLALLLYHFNWELPNKMKPEDLDMDEHFGMTVARKNKLFLIPTVYEAS
What are the official names of this protein?
Cytochrome P450 71D8, Cytochrome P450 CP7.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.