PharMolix/UniProtQA huggingface dataset:
Protein: HMGCL_BACSU
Sequence: MPYPKKVTIKEVGPRDGLQNEPVWIATEDKITWINQLSRTGLSYIEITSFVHPKWIPALRDAIDVAKGIDREKGVTYAALVPNQRGLENALEGGINEACVFMSASETHNRKNINKSTSESLHILKQVNNDAQKANLTTRAYLSTVFGCPYEKDVPIEQVIRLSEALFEFGISELSLGDTIGAANPAQVETVLEALLARFPANQIALHFHDTRGTALANMVTALQMGITVFDGSAGGLGGCPYAPGSSGNAATEDIVYMLEQMDIKTNVKLEKLLSAAKWIEEKMGKPLPSRNLQVFKSS
What is the function of this protein?
Involved in the catabolism of branched amino acids such as leucine.
What are the official names of this protein?
Hydroxymethylglutaryl-CoA lyase YngG, HL, HMG-CoA lyase, 3-hydroxy-3-methylglutarate-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA lyase family.
Protein: CDKL2_PONAB
Sequence: MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSKSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQLKVQKDARNVSLSKKSQNRKKEKEKDDSLGEERKTLVVQDTNADPKIKDCKLFKIKGSKIDGEKAEKGSRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLSAVAPGINSGMGTATIPIQGHRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSDDSGADLPQMEHQH
What are the official names of this protein?
Cyclin-dependent kinase-like 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL19_STRCO
Sequence: MSHLLDSVDAASLRSDVPAFRPGDTVNVHVRVIEGNRSRVQQFKGVVIRRQGAGVRETFTVRKVSFSVGVERTFPVHTPIVEKIELVTRGDVRRAKLYYLRELRGKAAKIKEKRDS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL3_NEIG1
Sequence: MTLGLVGRKVGMTRVFDEQGVSVPVTVLDMSANRVTQVKSKDTDGYTAVQVTFGQKKANRVNKAEAGHFAKAGVEAGRGLIEFALTEEKLAELKAGDEITVSMFEVGQLVDVTGTSKGKGFSGTIKRHNFGAQRTSHGNSRSHRVPGSIGMAQDPGRVFPGKRMAGQYGNTKATVQKLEVVRVDAERQLLLVKGAVPGAVNSDVVVRPSVKVGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ERA_STRP7
Sequence: MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGDDMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSRLVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMKRDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWVKVKKNWRDKKLDLADFGYNEREY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: NDK_PSYWF
Sequence: MAIERTLSIIKPDAVGGNHIGAIYSRFEEAGLKIVGAKMLHLDDEKAGGFYAEHKERPFYNDLVSFMTSGPVVVSVLEGENAIAKHREIMGATNPAEAAEGTIRKDFASSIDENAVHGSDSAESAKREIAYFFSDNEVLDRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL70_ARATH
Sequence: MLQFTLSYIKSLTKNLSIISPLPPPKPIKQNHQTKPAMNNFQPPPPSEMPDYNGLLGTDDIGGFRYGIGVSIGVLLLITTITLTSYYCTRNQLSSSPSQTNQDSTRIHHHHHHVIIDVVPGLDEDTIQSYPKILYSEAKGPTTASCCAICLGDYKGKHLLRQLPDCNHLFHLKCIDTWLRLNPTCPVCRTSPLPTPLSTPLAEVVPLASSVAATRMS
What are the official names of this protein?
RING-H2 finger protein ATL70, RING-type E3 ubiquitin transferase ATL70.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y4563_ARATH
Sequence: MANFPDKQYDSNNPYNIMITLSPFDVDRSTTIMMPKALLETNLFPFMEISTLVQLLQVQDKPKMIGVYDIDTQITTYVIIRQDGNNFKFHGWNDILKRKHYKAGDTIAFWWDLRHTRLNFKHVA
What are the official names of this protein?
B3 domain-containing protein At4g05630, Protein AUXIN RESPONSE FACTOR 46.
What are the subcellular locations of this protein?
Nucleus.
Protein: O163_CONAH
Sequence: MKLTCVMIVAVLFLTAWTFVTADDSRNGLENLSPKARHEMKNPEASKSNKRYECYSTGTFCGVNGGLCCSNLCLFFVCLFS
What is the function of this protein?
Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.
What are the official names of this protein?
Delta-conotoxin-like Ac6.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NOL9_DICDI
Sequence: MEINKNDNNNNINNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQKNNYRNYKPIKTGTLIQHQILQQTLSNFQTKNKVFQLGSDKLILIFKENETIYFHGTIQARSIIGSVEVYGYTITPQSTTYYPIYSPFCSPTLSITSNNSNNKLYTLKEIIENQLIKIPELVKNKLKENEKQIEIDEPTLAISSIIVLKILDDHCENPKMFTKKKIEIIDSFKLLKGFYPLYQPDFNTQLLTIPNEWLNLINTQFLYNDHCNNNGLSILTCGERNVGKSTFNRILINKLLKKYTHIIFIETDTGQTEFTPSGIMSIDIINSPLLGPPFTHCKNNPLKSYFFGDTSPKNNPEYFLNLSFQLIDCCNLIKQQYPNIPIILNTNGWLKSLGLHLTQEIIKYFKPTSIVQLINNNNNNNNNNNNNNNNNNNNNNNNNNLNDNLNNFINRFDSTVTFSQDCINQLFEDCDDDNDDNKNLKTTIITKLYSINSINNFSQSIYKPIFNLGSSEIRNLMFKSYFKLESKGSLSHQSPYQVSWKELKVKILTNNVPPSQTMYALNASLVGICIDEDPEKNYKYISYKVGNNLPTIINQSPLISQCIGLGLIRSIDMVNGYYYIITPIDPSLLEISNTILKGSIEIPQTLTISVSSKGKILVPYLQLDVLSSYGTGSDVMNRPSFFDD
What is the function of this protein?
Polynucleotide 5'-kinase involved in rRNA processing.
What are the official names of this protein?
Polynucleotide 5'-hydroxyl-kinase nol9, Nucleolar protein 9 homolog.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. NOL9/GRC3 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PSBK_HELAN
Sequence: MLNIFSLICLNSALYPSSLFFAKLPEAYAFLNPIVDVMPVIPLFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: 146R_IIV6
Sequence: MRKGYIYVIENNFDNHVYIGSTVDSLENRFRRHKADALKRPSCLFHTYMKKHGVDNFVIKLLKEVEIISILDLHLLEQNFIKDYGTLNTLHGKLKNLEINDKPTNVVLSKQTPFFTTIEPNIVKTEDVLKEITTNPSISLKELIDIFIEEEQNFGTILNEMTCQHKIYISKKLLKWIGYEGDYKKQRDSFKKLLKRHNIDFEELKSNDIECENYPEIKVDMANLSNGVISQSKWLILNIYNFKYI
What are the official names of this protein?
Putative MSV199 domain-containing protein 146R.
Protein: AMPA_BURTA
Sequence: MDFSIKGCDWSKGSAKGFLTGKSDCIVLGVFEAQTLSGAALDIDEAAKGLVSRVIKAGDIDGKLGKTLFLHEVSGIGASRVLLVGLGKQDAFSQKAYNDAVKAAWRALLGTKVVQVTFTLAQLPVPERASDWGVRAAILALRNETYKFTQMKSKPDASAPALKRIVFSVDPADEKAAKIAAKQAVALANGMDLTRDLGNLPGNVCTPTYLANTAKKLAKDWGLKADVLGLKQIQALKMSSFLSVAKGSVEPPQFIVLHYQGAAAKAAPVVLVGKGITFDSGGISLKPGEGMDEMKYDMCGAGSVLGTIRAVAEMGLKINVVAIVPTCENMPAGNANKPGDIVTSMKGLTIEVLNTDAEGRLILCDALTYAERFKPAAVIDVATLTGACIIALGHHNTGLFSKDDALAGELLDASREAGDPAWRLPLDDEYQDQLKSNFADLANIGGRPAGSVTAACFLSRFAENYPWAHLDIAGTAWKSGAAKGATGRPVPLLAQFLIDRAGA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTH_ECOSM
Sequence: MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALNIWLLVGTALGL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_PROMS
Sequence: MQIWPHKHIHTLANFSIKDYESVFELANRFDALKNAGTKKIPALQGTLVTSLFFEASTRTKNSFELAAKRLSADVQTFAPSSSSLTKGETIIDTAITYSAMGADTLVIRHSSSYITFEIAKKLDAINSKTSVLNAGDGLHSHPSQGLLDIYTLIKFFSPQTLNPEVLNSKKILIIGDVNHSRVARSNLWALSAFGADIILCGPKALIPDEFINFLKTPAPNQTEDPVKSRGSITISRSLEESIKTADAIIVLRLQKERMMENLLSSIDSYSLDYGLTPEKLSLNNKEIPILHPGPINRDIEISSKVVDRYPNCLINNQVANGIPIRMALLYLLQKHNK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: SYDND_ANADE
Sequence: MPRFITELKRTHSCGELTKADIGKEVVLFGWVNNRRDHGGAVFIDLRDRAGLTQVVFEEDVRPDVHELAGQLRLEYCVGVRGKVVSRGGNVNPKLPTGEIEVHASDLEIFNRSEPAPFQIEDKIDTGEEKRLQYRYLDLRRAPLQQTLMTRAKVNHLTRNYFTDKGFLELETPFMVKYTPGGARNFLVPSRLNPGKFYALAESPQLFKQLYMMAGFDRYFQIVRCFRDEDLRLDRQPEFTQIDVEMSFVEQNDVFDVMEGLVVKLWKEVLGIEIPRPFQRMPFEESMAKYGNDKPDLRFDMPHVVLTDLVRQHDGGGVPLMHEAVKAKGIVKAMRVPASANFSRTEIDKLEEYVKGMGAKGLARAKVGEGGEWTQSPLAKTITPALRQAINDACEAKAGDLLLFQFGKESVVHTVMANLRVHLAKRMGLIPEYGSGGAWRFLWVVNPPLFEYDEESGQWAAAHHAFTRPHDSDLQFLESDPGKVNCYRYDLVLNGFEIGGGSIRLHDPEVQARVFKAMGISDEEARSKFGFLLDALKMGAPPHGGIALGMDRLVMLLTGAESLRDVVAWPKTQKGTDLMTGAPGDVDARQLRELYVKSTFEPK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C13A4_CAEEL
Sequence: MSLSLLIAGALFIGFLTYYIWIWSFWIRKGVKGPRGFPFFGVILKFHDYENPGLLKLGEWTKKYGSIYGITEGVEKTLVVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAHLVLAQGHRWKRLRTLASPTFSNKSLRKIMSTVEETVVELMRHLDEASAKGKAVDLLDYYQEFTLDIIGRIAMGQTESLMFRNPMLPKVKEIFKKGGKMPFLIAGVFPIAGTLMRQLFMKFPKFSPAFGIMNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFIEEESTLGFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDRECPDPEVTFDQISKLKYMECVVKEALRMYPLASLVHNRKCMKKTNVLGVEIDEGTNVQVDTWTLHYDPKVWGDDASEFKPERWETGDELFYAKGGYLPFGMGPRICIGMRLAMMEEKLLLTHILKKYTFDTSTETEIPLKLVGSATIAPRNVMLKLTPRHSN
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Putative cytochrome P450 CYP13A4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: PYRC_CUPNH
Sequence: MTQKLTITRPDDWHLHLRDGAALAAVLPDTARQFARAIIMPNLKPPVTTVAQAQAYRARILAALPAGLQFEPLMTLYLTDNTTAEEIAAAKASGFVHGVKLYPAGATTNSDAGVTDIRRCYPALEAMQRAGLPLLVHGEVTDPSIDIFDREAVFIDRVMTPLRRDMPELKVVFEHITTKDAAEYVRDASGPVGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETHREALVAAAVSGSPRFFLGTDSAPHARGLKEHACGCAGCYTALHAMELYAEAFDAAGALDKLEAFASFNGPAFYGLPRNTGTLTLEREDWELPAELPYGDTTLVPLRGGETLRWKAR
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: SFSA_LAWIP
Sequence: MEKTIIYFPKGCVIGRFVKRYKRFFVNVLVDGEEVVAHTNNTGSMLGLLNSGTPVLLSPALNPTRKLQWTLELVWTGGTYPDENKLPSFPNKEGGVTPFHSGLGFWVGVNTLIPHKFFKLAFEAGLFPWTKGYSICNTETKIGMSRLDICLHGNGVPRLWVECKNVTLVENNVALFPDAVSLRGLKHLQELKKIIDSGERAATFYCVQRKDGKFFGPAASIDPQYTEMFWKVKKRGVEIYPYHIDITTKGLSLGPILPLLSE
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RPIA_CUPNH
Sequence: MTQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKERFAGAVSSSEASTRRLQQHGFKVLDLNEVDEIPVYVDGADEIDASGAMIKGGGGALTREKIVASVAKRFVCIADGSKLVQTMGTFPLPVEVIPMARAAVARKLQALGGQPRLRMTKEGGIYKTDNGNVILDVAGLKIDDPRGLEQAVNQVPGVVTVGLFALRGADVLLLGTGDGVQRTDY
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: YRAN_SHIF8
Sequence: MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVNERGGEIDLIMREGLTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: MUTS_XYLFA
Sequence: MREKPEGGKGMAEHTPLMKQYFAAKAEYPDLLLFFRMGDFYELFHQDARKAARLLDITLTQRGSSGGAPIPMAGVPVHAYEGYLARLIALGESVAICEQIGDPGLAKGLVERKVVRIVTPGTITDEVLLEERRDTLLMALSRSKNCYGLAWADLAGGRFLVNEVNSEEALEAELARLEPAELLLPDEDAWPEYLQQRNGVRRRPPWLFDADSGRRKLLAFFKLHDLSGFGIENNPQATAAAGALLGYIEETQKQRLPHLTSITMETVGEAITMNAATRRHLELDTRVDGESRHTLLGVLDSTVTPMGGRLLRRWLHRPLRLREVVRQRHAAVGSMIDRDLDNKLMETFRRLGDMERILTRVALRSARPRDISTLRDSLSLLPRLRELLNASDSPRLRVLYAELGEHDSTASLLVKAVAEQPPLKLTDGGVIASEYDVELDELRKLSNNADQFLIDLETRERESSGISTLKVGYNRVHGYYIEISKGQADKAPVHYTRRQTLTNAERYITEELKAFEDKVLSARDRALVREKLLYEQLLDTVGAQLEPLKRCAAALSELDVLVCFAERAQTLDWVRPELEHTSCLHIEGGRHPVVEAVREQRFEPNDLDLHPERRMLVITGPNMGGKSTYMRQNALIVLLAYIGSYVPASRALIGPIDRIMTRIGAGDDLARGQSTFMLEMTETSYILHHATAQSLVLMDEIGRGTSTYDGLALADAVARHLAHINRCYTLFATHYFELTALADETYEGGLSGIANVHFDAVEHSERLVFMHTVKDGPANRSFGLQVAALAGLPAAAVAHARRRLAELEQRGRESHVSEITPLALDAPQQCSLFASAPSAAQEALVALHPDELTPKQALEALYRLKALL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: ACP_NATTJ
Sequence: MATFDKVKDIVVDQLGVDEDQVTMEANFTEDLEADSLDIVELIMAMEEEFDMEISDEEAEKMSTVGDVVNYIEQNQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_CHLMU
Sequence: MLILDRSSPQIFISNEQQDVDIDLQSVQRLVILFLELQKVSTDQVYIYFLSDAALAQLHDEQFSDPSLTDTITLPIDRPGIQSFPHVLGEAFVSPRAAMRFLGQYTEAQLYHEISRYVVHSLLHMLGYDDQTDEDKRIMREQEDSSLTFLAQNQALLHPTV
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1787_METS5
Sequence: MTRIVVTAEIRPSEDEDKVKVAVANFFSFKSSKVEEGKYRLFVAESDTLSSLSKFHRVLREERILDAARKYLRRGIEGDRLTFMIHKQAAYVGKITFVDSENESPLGPITYTVFHRDLEAVVDWLAPRTSRGRPLWDNPMPED
What are the official names of this protein?
UPF0201 protein Msed_1787.
What is the protein family that this protein belongs to?
Belongs to the UPF0201 family.
Protein: Y1502_STAAC
Sequence: MSETFNQIKESFIEYLLFQYRFKSRIAVWVLNYIKVNEAKLANIHFVDTKINHHETLEIAEVGSHASAIQFTKRNIKLMNTNEIFDYIANHNCAFDIQIHFANVSKREQRLDDLIVAQLTESPSYQTYLHDLNSMAIDRHKHALLIDYLLHNIDLSLQMNEKQRFYQLTQILNTLKLVNKHNQFEDLADDN
What are the official names of this protein?
UPF0302 protein SACOL1502.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: CH10_VARPS
Sequence: MKLRPLADRVIVKRVDSETKTASGIVIPDAAAEKPDQGEVLAVGPGKRTEKGDLTALTVKVGDRVLFGKYSGQTVKVDGDELLVMKEDDLFAVVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIF_HUMAN
Sequence: MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
What is the function of this protein?
Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens (PubMed:15908412, PubMed:17443469, PubMed:23776208).  The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense (PubMed:15908412, PubMed:17443469, PubMed:23776208).  Counteracts the anti-inflammatory activity of glucocorticoids (PubMed:15908412, PubMed:17443469, PubMed:23776208).  Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known (PubMed:11439086, PubMed:17526494).  It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity (PubMed:11439086, PubMed:17526494).
What are the official names of this protein?
Macrophage migration inhibitory factor, MIF, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase.
What is the protein family that this protein belongs to?
Belongs to the MIF family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Note=Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens.
Protein: NADK_RHIWR
Sequence: MTEQRMALVASPTTAAQEAATELRAIYEWHPIERADLVVALGGDGFMLRTLHAMLDRHRILPVFGMNLGTVGFLMNDWKPDLLELRLQQARAITVLPLRMDVETVEGQRHSVPAINEVSLLRETRETAKIEVLVDGRVVLPELVCDGVLVSTPAGSTAYNLSAQGPILPLESSLLALTPISPFRPRRWRGAILPNKNAISFRVLDAIKRPVSAVADQREVRDVSLIRVGIDKTSPLTLLFDPEHALDDRITMEQFAV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_SERP5
Sequence: MKQFLDFLPLIVFFAFYKLYDIYVASGALIVATALALVFTWFKYRKIEKMTLITFLMVLVFGTLTLVFHNDLFIKWKVTIIYTLFALALLISQLVLKKPLVQRMLGKELTLPDKVWNSLNLAWAVFFLVCGLANIYVAFWLPQSVWVNFKVFGLTALTLVFTLLSGVYIYRHMPEEQKK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH60_STUST
Sequence: MAAKEVKFGDSARKKMLVGVNVLADAVKATLGPKGRNVVLEKSFGAPTITKDGVSVAKEIELKDRFENMGAQLVKDVASKANDEAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKATIAIVAELKNLAKPCTDSKAIAQVGTISANSDSSIGDIIAEAMERVGKEGVITVEEGSGLENELSVVEGMQFDRGYLSPYFINKPDTMVAELDSPLLLLVDKKISNIRELLPVLEAVAKAGRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVISEEVGLSLETATLEHLGNAKRVVLNKENTTIIDGAGQQADIEARVAQIRKQVEDTTSDYDKEKLQERLAKLAGGVAVIKVGAGTEVEMKEKKARVEDALHATRAAVEEGVVPGGGVAWVRALQAISELKGENEDQNVGIALLRRAVEAPLRQIVTNAGGEPSVVVDKVKQGEGNYGFNAASDTYGDMIEMGILDPAKVTRSALQAAASIGSLMITTEAMIAEVAEDKAAGGMPDMGGMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
Protein: IF1_XANCB
Sequence: MSNDDSIEFEGSVSETLPNTTFRVKLENGYEIIAHISGRMRKNYIRILTGDRVKVEMTPYDLTKGRITYRMK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUD_XYLFA
Sequence: MLVSMSDDLAGFSRQTTVPDGAAGRRFDAVLAELFPEFSRSRLTEWIKSGDVLLNGVLVRPRDPVYGGEVVRLQVVPDIRTDAVPQDIPLDILYEDEHVFVLNKPAGLVVHPGAGNPDGTLVNALLHRDPALAAVPRAGVVHRLDKDTSGVMVVARTLQAQTALVEQLSSRQVHRQYLAVVVSALVSGGTVNAAIERHPRDRLRMAVSDTGKEAVTHYRLRERFRAHTALECRLDTGRTHQIRVHMAHLRHPIVGDRLYGGSLKLPKVGTDALVVMLRGFKRQALHAEVLEFLHPVGALPVRIVAPVPEDLCQLLAVLREDSALFFERERR
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase D, 23S rRNA pseudouridine(1911/1915/1917) synthase, rRNA pseudouridylate synthase D, rRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.