PharMolix/UniProtQA huggingface dataset:
Protein: COAA_ECO8A
Sequence: MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA_METJA
Sequence: MHELSYANAMLEAILNSIKKEEEKGKKIKKVTEINLEVGELTFINVEQLKFAFEVIAEGTVCEGAKINVEFIKPKCKCLDCGYEGEPEILDEFEVYCPKCKSIRLKLSGGKEFNIKNATVEYED
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: NANA_STAAT
Sequence: MNKDLKGLYAALLVPFDENGQVNEQGLKQIAQNAIETEELDGLYVNGSSGENFLLNTEQKKQVFKVAKEAVGDKVKLIAQVGSLDLNEAIELGKYATELGYDALSAVTPFYYPFTFEEIRDYYFDIIEATQNNMIIYAIPDLTGVNISIEQFSELFNHEKIVGVKYTAPNFFLLERIRKAFPDKLILSGFDEMLVQATISGVDGAIGSTYNVNGRRARKIFDLARQGQIQEAYQLQHDSNDIIETVLSMGIYPTLKEILRHRGIDAGLPKRPFKPFNEAHRQTLDQLIAKYDL
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_NEIMF
Sequence: MLPFFPEPSLSYTQQNRTAVLLLNLGTPDAPTAQAVRPYLKSFLTDRRVVELPKWLWYPILHGLVLTLRPKKSAHAYEKIWFKEGSPLEVYTARQAAALAKRMPDLIVRHAMTYGNPSVADVLSELKAQGAGRLLVIPMYPQYAASSSGAAVDKVCEQLLLQRNQMSVRTVSRFYDDTGYIDAMKNHILRYWAEHGRGKKLMLSFHGVPQKHHDLGDPYPDECRHTAKLLAEALELTEDQYVVSFQSQFGRAKWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLETMEEIALMGREQFYEAGGKSYRYIPCLNDNPDWIDALVALAEENLGGWR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHB_CHLAA
Sequence: MRDDDDLVPPKWRPLFNNQDWLLHDIVVKSFYGFGVIAAIAHLLVYLWKPWLP
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-808/866 beta chain, Antenna pigment protein beta chain, Bacteriochlorophyll a-binding protein.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: SYI_SALTY
Sequence: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGFDSPYVPGWDCHGLPIELKVEQEFGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGRIIKNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFRAVDQDAVKAKFGLPGVSGPVSLVIWTTTPWTLPANRAISLAPDFDYALVQIDGQAVILAKDLVESVMQRIGAAEYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVIELLKEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDKEGLRQQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKETQELLPIERTLAAMEEVAKRVEVDGIQAWWDLDPKEILGEDADQYEKVPDTLDVWFDSGSTSYSVVDARPEFAGHAADMYLEGSDQHRGWFMSSLMISVAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFNPATDMVKPEEMVVLDRWAVGCAKTAQQEILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPIMSFTADEIWGYLPGEREKYVFTGEWYDGLFGLEENEEFNDAFWDDVRYIKDQVNKELENQKANGIKSNLEAKVTLKYADDANGTIKKLKLLGEEVRFIFITSQFVISEQAGGIDDENIQYNAGNTTVQAVVTRAEGDKCPRCWHYTTDVGKVAEHADICGRCVSNIAGNGEQRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_BURL3
Sequence: MTKSELVAQLASRFPQLVLKDADFAVKTMLDAMSDALAKGHRIEIRGFGSFGLNRRPARVGRNPKSGEKVQVPEKFVPHFKPGKELRERVDGRAGEPLKADDPDDER
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: BRNQ_LACDL
Sequence: MKEKLTHAESLTISSMLFGLFFGAGNLIFPAYLGEASGANLWISLLGFLITGVGLPLLAIASLGMTRSEGLLDLSGRVSHKYSYFFTCLLYLTIGPFFAIPRSFTVPFETGISALLPSGMAKSTGLFIFSLIFFAIMLFFSLRPGQIMDWIGKFLTPAFLLFFFFIMIMALLHPLGNYHAVKPVGEYASAPLISGVLAGYNTMDALAGLAFGIIVISSIRTFGVTKPEKVASATLKTGVLTCLLMAVIYAITALVGAQSRTALGLAANGGEALSQIARHYFPGLGAVIFALMIFVACLKTAIGLITACSETFAEMFPKTLSYNMWAIIFSLLAFGIANVGLTTIISFSLPVLMLLYPLAISLILLALTSKLFDFKQVDYQIMTAVTFLCALGDFFKALPAGMQVKAVTGLYGHVLPLYQDGLGWLVPVTVIFAILAIKGVISKKRA
What is the function of this protein?
Branched chain amino acid transport system which is involved in the uptake of leucine, valine and isoleucine (PubMed:8544834).  The proton motive force is probably the driving force for transport (PubMed:8544834).
What are the official names of this protein?
Branched-chain amino acid permease BrnQ, BCAA permease, Branched-chain amino acid transport system carrier protein, Branched-chain amino acid uptake carrier.
What is the protein family that this protein belongs to?
Belongs to the branched chain amino acid transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMG_BRADU
Sequence: MRPERESFDVIVIGGGHAGCEAAAASARMGAATALVTHRFSTVGAMSCNPAIGGLGKGHLVREVDALDGLMGRVGDAGGIQFRVLNRRKGPAVRGPRAQADRKLYAAAMQAAIRETEGLSVIEGEADELIVVEGRVTGLRLADGREFGAGSIVVTTGTFLRGLIHLGEKNWPAGRVGEAPAMGLSSSFERAGFTLGRLKTGTPPRLDGTTIDWSAVEMQPGDEPPEPFSVMTDRITTPQIQCGITRTTAATHEVIRANVHRSPMYSGQIKSSGPRYCPSIEDKIVRFGDRDGHQIFLEPEGLDDSTVYPNGISTSLPEEVQLAILASIPGLERVKMVRPGYAIEYDHIDPRELDPTLQTKRLRGLFLAGQINGTTGYEEAAGQGIVAGLNAALAASGAALTVFDRADGYLGVMIDDLVTRGISEPYRMFTSRAEYRLTLRADNADQRLTEKGIALGCVRSARTLHHRTKMEALNAARTLSKSLTITPNEAIKHGLSLNRDGQRRSAFELMAYPDIGWSQVRAIWLELSAIDPVIATHLEIDAKYDVYLERQSADVEAFRRDEGLVLSEVDYQLVPGLSNEVRAKLEKARPFTVGQAGRIDGMTPAALGILAAYLRREARKTSKAIA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_BORPE
Sequence: MSIERTLSIIKPDAVAKNVVGQIVARFEQAGLKVIAARMQQLSRTDAERFYAVHKERPFFKDLVDFMVSGPVFVQVLEGESAIQKNRDLMGATDPKKAAPGTIRADFADSIDANAVHGSDAPETAAVEVAFFFPEINIHSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FGF17_MOUSE
Sequence: MGAARLLPNLTLCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAERQKQFEFVGSAPTRRTKRTRRPQSQT
What is the function of this protein?
Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain.  Required for normal brain development.
What are the official names of this protein?
Fibroblast growth factor 17, FGF-17.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: TM135_CAEEL
Sequence: MGALSKLAHSLGQPILTATCYETIHTWNPDCNGAFFDALPVGLIFSLKTYASFYLITNVVSKRGRLDKINWKKFGIDVCQSSLFLVTNMCFFLILLCKFRKWLGFFTPITMGLVSSILASGIAILVEKKSRRPALALYLINLASETYYRHLANHGYVTMHTYGECIPFGIGLMLFTWLQSIGRLPKSFNGFMNVALKSNVSENLINEKKIPDNFRLFLEKLRSDYKKTELCNHPHSCVSHSVESFAKNMTFGLTASSVLTVIRNVRTIIKNPLNLITLLVSKENLKLPLFAGFLPFIFNATRCSLNRVKYVPPVLNNVFSAGLASVAMAFYPTVSIAMYCLWKAIETVYFDLVDRGYLPKFKNGEVILYAITTGYVLWNAVVEPRAIRRGYLNFLFGLVGGKISLFNRRLYDHFGFVSRDVYTKIPEFDPKYAMINPMLYMPLVE
What is the function of this protein?
Involved in fat storage.
What are the official names of this protein?
Transmembrane protein 135 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM135 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: KHK_RAT
Sequence: MEEKQILCVGLVVLDIINVVDKYPEEDTDRRCLSQRWQRGGNASNSCTVLSLLGARCAFMGSLAHGHVADFLVADFRRRGVDVSQVAWQSQGDTPCSCCIVNNSNGSRTIILYDTNLPDVSAKDFEKVDLTRFKWIHIEGRNASEQVKMLQRIEQYNATQPLQQKVRVSVEIEKPREELFQLFGYGEVVFVSKDVAKHLGFRSAGEALKGLYSRVKKGATLICAWAEEGADALGPDGQLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSKGNSMQEALRFGCQVAGKKCGLQGFDGIV
What is the function of this protein?
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
What are the official names of this protein?
Ketohexokinase, Hepatic fructokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: CYB_ALLAL
Sequence: MAPNLRKSHPLLKLINNSLIDLPTPSNISAWWNFGSLLGICLLTQILTGLLLATHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLNKETWNTGIILLLALMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLAFIHLTFLHESGSNNPLGIPSNCDKIPFHPYFSLKDILGFIVMFLPLTTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLTPLLHKSKQRAMTFRPFSQFLFWTLVANLFILTWVGSQPVEHPFIIIGQLASLTYFTILLLLFPIIGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RUVA_COLP3
Sequence: MIGRLRGMLVEKNSPEILIECAGVGYEVTMPMTSIYALPELEQQATIYTHFVVREDAQLLYGFANKVERKLFRLLIKVNGVGPKLALAILSNMSADQFVSCVRHDDISAIVKIPGVGKKTAERLLIEMRDRLKDWQAQQIHLVSDDGVIPEQLSAELSQETTFVNDNKGDAINALLSLGYKQVQADKAVKSVYNRGMSSENIIRDALKSMI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: FLOA_STAAN
Sequence: MFSLSFIVIAVIIIVALLILFSFVPIGLWISALAAGVHVGIGTLVGMRLRRVSPRKVIAPLIKAHKAGLALTTNQLESHYLAGGNVDRVVDANIAAQRADIDLPFERAAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMNGIEVKAKARITVRANIARLVGGAGEETIIARVGEGIVSTIGSSKHHTEVLENPDNISKTVLSKGLDSGTAFEILSIDIADVDISKNIGADLQTEQALADKNIAQAKAEERRAMAVATEQEMKARVQEMHAKVVEAESEVPLAMAEALRSGNISVKDYYNLKNIEADTGMRNAINKRTDQSDDESPEH
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Present in detergent- resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts, with 1 focus per cell; lost when cells are treated with squalene synthase inhibitor zaragozic acid. These rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: AGOG_METMP
Sequence: MRNLEKINELLEIFGHFDVNFAKTMEEKIDTQYFVLENLKNSMNNDEMFIKLVILNSIVSYQLCTTGELWWEEFSKYWSKHDANNENLGESYVNFLENSKGNKRLLNVKIKRIERITPFLENLNLLDFKTYYSDMEKLLENLSKYLNSKKNSKTVVFAVKMFGYASRIVFNEFFPYPMNIEIPKDSRIEKYTLKFTDENPIKFWNEVSKTAKIPPLHIDSIIWPVLGRNFDFKSCENKLDENFRYLLKLTEL
What is the function of this protein?
DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
What are the official names of this protein?
N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, AGOG, DNA-(apurinic or apyrimidinic site) lyase, AP lyase.
What is the protein family that this protein belongs to?
Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
Protein: YR27_CAEEL
Sequence: MRYFNCLLYWFLSIFIVVVYYNEILTTPIIEPSVEYVLCSTLLDYLKAPIPVLLIDFEILEQIERNSCHMQTEKRVKIGVDKTQENAHLLQKDSRFHVVNYKNSTKTDHLDFEVTTFTKKSIPKRFGARIVGNVQVPLDIQQFMGFWQRSMVLDCKKERNEISQPSTASNDLAALQNVLIENGMFPFLNGRTLLNWYKECTTKHEIFNFMVMASNFNLNFLENLEKGQSKLKLVQKNRTVGNGLRITVALNEVKAHIGLLYKELNEDGSVVHWTKGNNFKNHTIRFSTYDPWCSTDIHGHLFWISCTPGTRIAEEFANTKFTDFV
What are the official names of this protein?
Uncharacterized protein W02B3.7.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RAS4B_HUMAN
Sequence: MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVHLPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVHQGVAQLKDFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTDDAGRPQTAYLQCKCVNELNQWLSALRKVSINNTGLLGSYHPGVFRGDKWSCCHQKEKTGQGCDKTRSRVTLQEWNDPLDHDLEAQLIYRHLLGVEAMLWERHRELSGGAEAGTVPTSPGKVPEDSLARLLRVLQDLREAHSSSPAGSPPSEPNCLLELQT
What is the function of this protein?
Ca(2+)-dependent Ras GTPase-activating protein, that may play a role in the Ras-MAPK pathway.
What are the official names of this protein?
Ras GTPase-activating protein 4B.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein.
Protein: NGK1_YEAST
Sequence: MTIESTLARELESLILPADSIVNVVDQFQEELLSRLQTNTISMLPQCLVPDKRSRWNPEDKILTIDFGGTRLKFAIISLPQIVIEYNDAFELTYNIVDSNFFNQIIYTICTRLAANGYIKKKNESSEASKFFVSVTFSFPLNPEGEVVAMGKGFVMTDTLQGSTVKQLIQSSFHRIISENIEEFFCTMNVCHVINDAIAVSLTSKFICENDSISLIIGTGTNACFEVPYGYLPPFKRDALRETLPSSYNKETLNFKHVLINSEIGFIGKNVIALQPFDIHGAISYEMPLECVTSGKWLPLSLKNILLQYNIIPKNFPVEFNGELVCQLAEDCTNAWFENEHYALICQIARLLIKRAAFYVAAIVQAIDIITGCKNYNFIHIGYVGSFLHNSNFYREQIKYYSSIHIKLQFLNHSNLLGAAIATYLNKSDNQVQ
What is the function of this protein?
N-acetylglucosamine (GlcNAc) kinase that transfers a phosphate onto GlcNAc to generate GlcNAc-6-phosphate, which can be a precursor for glycan synthesis (PubMed:36216916).  Can utilize a broad range of NTPs, namely ATP, CTP, GTP, ITP, and UTP, as phosphoryl donors (PubMed:36216916).  Shows only low glucose phosphorylation activity (PubMed:36216916).  NGK1 may play a role under a certain condition as an alternative supply pathway GlcNAc-6-P as a precursor of UDP-GlcNAc (Probable).
What are the official names of this protein?
N-acetylglucosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
Protein: RNPA_BRUME
Sequence: MKSKKQILRLRKRAEFLTVRNGEKRRGPLFLMAVRERTEEESNAAKTGDNPRVGFTVTKKNGNAVIRNRIRRRLKEAIRCHAGRDMAPSTDYVIVAREQALNAPFSQLTEELSRRITAKGERRSGGKRRTERPEPGPVNGK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RRF2M_DROPE
Sequence: MLKYALHSGGMPRNRLLRQLSAYIFRRSYSSNIRNIGILAHIDAGKTTTTERMLFYSGKTRSLGEVHRGNTVTDYLTQERERGITICSSAVTFPWSGNRINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWTQADKHKLPRLAFVNKMDRPDADFDKCVNDLRTKLETQPVCIQYPSKNQDGLLAINDVITLEQLTWQPKDLGRSYSKTKLEPSDDLRQLQEKRNELIDQLSGLDDELADVVISTESFDNVSNALIERALRRATCQQKVVPVLLGSAYKNVGIQRLMDAVNTYLPAPEERNQIYDCFGNEVAGKVFKIVHDKQRGPLTLVRILRGEIKRGMRLICSRGQAEVVSKLYEPLADEYREVGAVQSGDVVICAGLKSTVTGDLLTSSQTALRNAQKRLKQSQGTVSADEDEELDTDELFGIDRQIPDAVYFCSIEPPSVSSQTAMEQALRQLQREDPSLRVSYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETIESPSLTTLSVEKEIAGSKQNVSLTLEVVKDHDELFSLDKSPENLSNLNTLRPRTLQVIRKGSVSALERGPRVGGQVVDTQIRLHNAIIGRGTADSFVMATAAQCVQKLLSTSGTRLLEPIMALQIVAPSERISGIMADLSRRRALINDVLPKGERNKMILVNAPLAELSGYSSALRTISSGTASMTMQPSGFSGMNAVDESLAERRVQGLE
What is the function of this protein?
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.  Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
What are the official names of this protein?
Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ANGP4_MOUSE
Sequence: MLCQPAMLLDGLLLLATMAAAQHRGPEAGGHRQIHQVRRGQCSYTFVVPEPDICQLAPTAAPEALGGSNSLQRDLPASRLHLTDWRAQRAQRAQRVSQLEKILENNTQWLLKLEQSIKVNLRSHLVQAQQDTIQNQTTTMLALGANLMNQTKAQTHKLTAVEAQVLNQTLHMKTQMLENSLSTNKLERQMLMQSRELQRLQGRNRALETRLQALEAQHQAQLNSLQEKREQLHSLLGHQTGTLANLKHNLHALSSNSSSLQQQQQQLTEFVQRLVRIVAQDQHPVSLKTPKPVFQDCAEIKRSGVNTSGVYTIYETNMTKPLKVFCDMETDGGGWTLIQHREDGSVNFQRTWEEYKEGFGNVAREHWLGNEAVHRLTSRTAYLLRVELHDWEGRQTSIQYENFQLGSERQRYSLSVNDSSSSAGRKNSLAPQGTKFSTKDMDNDNCMCKCAQMLSGGWWFDACGLSNLNGIYYSVHQHLHKINGIRWHYFRGPSYSLHGTRMMLRPMGA
What is the function of this protein?
Binds to TEK/TIE2, modulating ANGPT1 signaling.  Can induce tyrosine phosphorylation of TEK/TIE2.  Promotes endothelial cell survival, migration and angiogenesis.
What are the official names of this protein?
Angiopoietin-4, ANG-4, Angiopoietin-3, ANG-3.
What are the subcellular locations of this protein?
Secreted.
Protein: TPIS_LEIXX
Sequence: MRRVPLIAGNWKMNLDHLQSIAVVQKLAWTLKDAGHDFGAVEVAVFPPFTDLRSVQTLVAADKLPIAFGGQDVSEHDSGAYTGEIAASFLAALEARYVIIGHSERRTLHNETDEQVAAKTAQAVKNGISPIVCVGETAEDLEKHGASAVPVAQLRAALAGIDSAADFVVAYEPVWAIGSGQAATPEQAEQVAAALRAVIAEALGDEVAAKTRILYGGSVKSGNIAGFMRETNVDGALVGGASLDVAEFAAIIRYQKHVI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHEA_MICDP
Sequence: MKSVVTTVIAAADAAGRFPSTSDLESVQGSIQRAAARLEAAEKLANNIDAVATEAYNACIKKYPYLNNSGEANSTDTFKAKCARDIKHYLRLIQYSLVVGGTGPLDEWGIAGQREVYRALGLPTAPYVEALSFARNRGCAPRDMSAQALTEYNALLDYAINSLS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
C-phycoerythrin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the periphery of the phycobilisome rod.
Protein: RLME_VIBCM
Sequence: MSKQKHSASSTRWLKEHFDDKYVNEAKKKGYRSRAIFKIEEIQNKDKLLKAGMTVVDLGAAPGGWSQFAAKVVGEGGRVIACDLLPMESIAGVSFLQGDFREEAVLNALLDRIQPDMVDVVMSDMAPNMAGNLSVDQPRAMYLVELALDMCRQVLAPNGSFVVKVFQGEGFDDYVKAVRDLFKVVKIRKPDSSRSRSREVFIVATGYKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSK_SOLTU
Sequence: MAGEKIGIAKDVTELIGNTPLVYLNNVVDGCVARVAAKLESMEPCSSVKDRIGYSMITDAEEKGLIKPGESVLIEPTSGNTGVGLAFMAAAKGYKLIITMPSSMSLERRIILRGFRSELVLTDPAKGMKGAISKAEEIKAKTPNSYILQQFENPANPKIHYETTGPEIWKGSNGKVDALASGIGTGGTITGSGKYLREQNPNVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPGVLEVNLIDDVVQVSSEESIEMAKLLALKEGLLVGISSGAAAAAAIKVAKRPENAGKLIVVIFPSFGERYLSSVLFETVRREAENMTVEP
What are the official names of this protein?
Cysteine synthase, CSase A, CS-A, O-acetylserine (thiol)-lyase, OAS-TL A, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Cytoplasm.