PharMolix/UniProtQA huggingface dataset:
Protein: RPIA_STRR6
Sequence: MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALLMEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREKDGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTSKKGK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RSSA_DANRE
Sequence: MSGGLDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYVYKRKSDGVYIINLKKTWEKLLLAARAIVAIENPADVCVISSRNTGQRAVLKFASATGSTTFAGRFTPGTFTNQIQAAFREPRLLIVTDPRADHQPLTEASYVNIPTIALCNTDSPLRYVDIAIPCNNKGPHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKAVGKEEFQGEWTAPVPDFNQPEVADWSEGVQVPSVPIQQFPAGIEAPGKPAPAEVYAEDWSAQPATEDWSAAPTAQAGDWGGATADWS
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Also functions as a cell surface receptor for laminin.  Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.  May play a role in cell fate determination and tissue morphogenesis.
What are the official names of this protein?
40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Laminin receptor 1, LamR, Laminin-binding protein precursor p40, LBP/p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus. Note=67LR is found at the surface of the plasma membrane, with its C-terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus.
Protein: UBIG_ECO24
Sequence: MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-octaprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone-8 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: SYT_MARN8
Sequence: MPVITLPDGSHRSFAEPVTVHDVAADIGAGLAKAALAGKVNGKLVDTSHLIENDTELAIVTERDEDGVDIIRHSTAHLMAMAVQELFPGAQVTIGPVIENGFYYDFKYERPFTNEDMARIEKRMEELAKQDLPVSRSIMSRDEAIKLFNEMGEEYKVRIIEDIPGEEDLSFYRQGDFIDLCRGPHVPSTGKLKAFKLTKVAGAYWRGDTSNEQLQRIYGTAWGNKKDLKAYLHRLEEAEKRDHRKIGKKLGLFHMQEEAPGMVFWHPDGWSLYQEVEQYMRAQQHKHGYKEIKTPQVVSRTLWEKSGHWDKFKDDMFTTESEKHDYAIKPMNCPCHVQVFNQGLKSYKDLPLRLAEFGSCHRNEASGALHGLMRVRGFTQDDAHIFCEEDAIQEEVSAFIAMLHEIYADFGFSEILYKLSTRPEKRVGSDEVWDKSEAALEQALNREGVDWELLPGEGAFYGPKIEFSLKDCLGRVWQCGTIQVDFSMPGRLGAQYVADNSERKTPVMLHRAVLGSFERFIGILIEEYEGAFPTWLAPTQVAVLNITDKQRDYCQNLAKKLDSSGYRVNADLRNEKIGFKIREHTLNKVPYLVVVGDKEIENNAVAVRTRKGEDLGTMSVDDFEKLLAADVERKGRTKTEI
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SULA_YERPS
Sequence: MRTQSLKPYHANYHSLTTNDSPARVDAPTDSGLISEFVYSENQPVVTQLLLPLLQQLSKQSRWLLWLTPQQKLSRSWLKQSGLPINKVVQLRQINPLSTVEAMEKALLTGNYSVVLGWLPELTEDDRIRLRLAAKLGNAYGFVMRPLNDTKVGSGQCATLKIHSYLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: YBJQ_ECODH
Sequence: MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RL34_ACICJ
Sequence: MKRTYQPSKLVRKRRHGFRSRMETVGGRKVLASRRAKGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RS14Z_STAAE
Sequence: MAKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: Y1460_STAAC
Sequence: MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVKTSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQASQMVDANVTVIDSKSISFGLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGNLMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSIGVAHANVIEYVDKLKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein SACOL1460.
Protein: ARGO_YERPS
Sequence: MLAVYLHGFILSAAMILPLGPQNVFVMNQGIKRQHHLMSASLCALSDIILICAGIFGGSALLSRSPLLLALVTWGGVAFLMWYGWGALMAAWRGDGVASSATSVTQGRWRILVTLLAVTWLNPHVYLDTFVVLGSLGGQLLPDIRPWFALGAVTASIVWFFALALLAAWLSPWLNRPVAQRIINLFVGGVMGFIAFQLARQGFGL
What is the function of this protein?
Involved in the export of arginine.  Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
What are the official names of this protein?
Arginine exporter protein ArgO.
What is the protein family that this protein belongs to?
Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PMA6F_HUMAN
Sequence: MLQDWCRRMGVNAERSLLILDIPDDCEEHEFQEAVRAALSPLGRYRVLIKVFRKELGARAALVEFAEGLNQSLIPRQIAGKGGPWKVISLPQALDAEFQDIPSFPAQPQGQAVARGAGEAGAAGEAGSVGEAGGVNEERSAGEDEAGGIGEAGGVGEAGAAGEAGAAGEAGAAGEAGGAGEAGGAGEAGGAGEEGGTGEEGGAGEAGGAGEEGGEDEAGAAGEAVGAGVVEAWTQSWRQTLRPLVKTMAYRELRPFSGREQPGCVEESFESWLEDAKDMLQLWCHASERERRRRLLDSLDGLALDIVSGLLEEDPDFSAQDCLTALGQVFRSRDTWMTSRMKFLTCTQGPQEGLFAFVVRLEGLLQKAVEKGAVHPAMANHLRLRQVLSRARPSEALQDTLRRMQLERRPPDFLRLLRLIRDMEAWAASLARSQQGVAWAAAPVESEDPAAAQASPAQGDASEADPGAEDADEAASTTKEAARVAPATGEDENAPAGLEGLGQGRSPDAPGGLPARMGSAVDMAPGGPSWEPEGLVQVGGQEAEEPPQEGLKPILEESENEDEDGAGEAGKPKSPPGK
What are the official names of this protein?
Paraneoplastic antigen Ma6F.
Protein: DEF_SACD2
Sequence: MALLPILEFPDPRLRTIAKPVAKVDQRIRTLIDDMFETMYDAPGIGLAATQVNVHEQVLVIDLGEETKEPMVFINPSIEILDQEHYEYEEGCLSVPGFYEQVSRPKHIRVTALDRDGKEFVIEPEGLLAVCVQHEMDHLNGKLFVDYVSNIKRQRIRKKLEKQHRQAAQSVG
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: SYY_MESFL
Sequence: MNIIKELEWRGLVKQITNEERLLKAQNDGAAVYCGFDPTADSLHVGHLMMIVTLKRFDKAGFQAIGLIGGGTGMIGDPSFKADERKLQTDEQVKFHATAIQNQLLRIIPDVTFANNVDWLGNMSLIDFLRDVGKDFNISYLLNKDSIATRISTGLSVTEFSYTMLQAYDFYNLYINHNCKVQIGGSDQWGNITSGTDYISTRVGSANTEAAGFTIPLLTKSDGQKFGKTESGAVWLDSNKTSVYDFYQFWINQDDNDCVKMLKYLTFLTKEEIDELEAKHKEAPHLRTMQKTLASEITKFVHGDKELNKAIKLTDAFFTGNILNLDDDLLELAIKSIPTIQLEKTTSAIDAIVNVNAASSKREAREFINAKAISFNDVAVQDENMLLSEIKTIKNNKIIVKKGKKKYYLLEIK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_OCEIH
Sequence: MTHVSFNYEKALSFFEKQEITNLEPFVHTAHQMIHERIGAGKDFLGWLDLPRNYNREEYTRIKAAADKIKKDSDILLVIGIGGSYLGAKAALEMLNHSFQNLLSKDQRQVPQIIFVGHHLSSTYMTELFDILKDKDFSINVISKSGTTTEPAIAFRVFKKYLEEKYGQDEAKKRIYATTDRSKGALKTTADSNDYETFVIPDDVGGRYSVLTAVGLLPIAASGINIDDMMEGAKAGMEDLANPVISENPAYQYAAVRNILYQKGKVTELLINYEPNLQYFSEWWKQLFGESEGKNQKGIYPSSANFTTDLHSLGQYIQEGRRNIFETILHVNEPKKDFTLEKEESDLDGLNYLAGKSIHEINDKAFQGTLLAHTDGDVPNLIVEVPRLDAYTFGYLVYFFEKACAISGYILGVNPFDQPGVEAYKKNMFALLGKPGFEDQKEALEKRL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUGB_GLARU
Sequence: SLFSLIKAGAKFLGKNLLKQGAQYAACKVSKEC
What is the function of this protein?
Shows antibacterial activity against both Gram-negative and Gram-positive bacteria.
What are the official names of this protein?
Rugosin-B.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL35_CHLTA
Sequence: MPKMKSNKSVAARFKLTGSGQLKRTRPGKRHKLSKRSSQQKRNLSKQPLVDQGQVGMYKRMMLV
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ADEC1_BRASO
Sequence: MDLAQDIADDLMIDAAQEVRIRQDLVLTALGHRPADRALRVGRLLDVHSRTWSEDQEIVFKGRRIAWVGPAGSYRGEVRERVQRPDLAAVPGFGEVHKHIESSHLTPEWEAALVLPRGNTWTCEASHEFSNVNGARNLEFWFEARRRGSPLKIFPQPGSAVPPTAYEWGGGWYGGAEQASFMRESLMVTGLDEVMDWPAVWNPDNPSYERLWGMIGATFAARGVVEGHASGLRELPEINAFAAAGLASDHEVQTPEETWDKLTRGLFIELRIYAMPEIIGWLLKKGLQDWSQIAFTTDDRSASHTLALGASDHNARVAIEAGLAPEIAIQCLTINPARHMRLTPFVGSLAPGRFGDVVLLSDVGKLEIAEVWADGAQVSEGTRYLGDVPRIAWPDWATQTINIKREIKAEDFALPAAPGRTTMQAAVIRPFHWHPEFYTFELAVRDGAVQRDESQAITKFAIVDRFSGDGLVSKMFWKGCGPRTPETALACSVAHDKHNIWAVGSSDAAMAKAVNALVAQQGGWALVREGELAATVRFEVGGLMSCRRAEALDAEMQALYAEGRKVDWMYEPTFRPRWYPGFPERLMFATLTCAPWSWVLVAPCEQAPQGFINVQTGKTHPVVW
What are the official names of this protein?
Adenine deaminase 1, Adenase 1, Adenine aminase 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: PGK_DECAR
Sequence: MNVIKLTDLDVSGKRVFIRADLNVPQDEAGNITEDTRIRASLPSIKYCLEKGAAVMVTSHLGRPTEGELNHEDSLMPVAVRLGQMLHTSVRLITDWVDGGFEVKPGEVVLLENCRVNKGEKKNNDELAQKMAKLCDIYVNDAFGTAHRAEATTHGIAKYAPVACAGMLMGAEIDALSKALHEPKRPLVAIVGGSKVSSKLTILKSLASKVDQLIVGGGIANTFLLADGKRIGHSLAEPDLVKEAHTIMDIMKERGAEVPLPTDVVVADEVSALARANKISVDDVHANDRILDVGPKTAAKFAEIIANAGTIVWNGPVGVFELPQFAGGTKMMASAIAHSEAFSIAGGGDTLAAIAKFHIADDVGYISTGGGAFLEFLEGKTLPAIAILEERAA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRE_PSEA6
Sequence: MEQYLSLFIRSIFLENMALFYFLGMCTFLAVSKKVKTAMGLGVAVIVVLTISVPVNQLVYANILAPGALGWAGFPDTDLSFLSFLTFIGVIAALVQILEMTLDKFFPALYNALGIFLPLITVNCAIFGGVAFAVQRDYTFTESIFYGAGSGAGWALAITLLAAVREKLKYADMPEGVRGLGSVFMIAGLMALGFQSFSGVSI
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLS2_PITHY
Sequence: MAFLKKSLFLVLFLGLATLSICEEEKRETEEEEYNQEEDDKSEEKRFLSLIPHAINAVSTLVHHFG
What is the function of this protein?
Has antimicrobial activity.  No hemolytic activity.
What are the official names of this protein?
Phylloseptin-H2, PLS-H2, Phylloseptin-2, PS-2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXC_POLSJ
Sequence: MLAQRTLKSLTKAVGVGLHSGQRVELTLRPAPPDTGIVFRRVDLPQPVDIVISAQAVTDTRLASTISAGGAKVHTVEHLMSACAGLGIDNLYIDITAEEVPILDGSASSFVFLLQSAGIELQSAPKRFIRVLKPVEVREGEGATAKWARLSPYEGYKLSFEIDFDHPAVDSTGQRVEFDLSSGSYSRDIARARTFGFTKDVEMMRANGLALGGGLDNAIVMDDYKVLNSEGLRYNDEFVKHKILDAMGDLYLLGKPLLAAYSAFRSGHAMNNKLLRELLAHQDAYEVVTFADEKRAPQGFATLARAW
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RNC_STRPN
Sequence: MKELQTVLKNHFAIEFADKKLLETAFTHTSYANEHRLLKISHNERLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKLGKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITDYKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQEAAKNAVEKGLDSCI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_YERPS
Sequence: MNDSEFHQLADQLMLYIEETLDGFTGDSDIDYETNGGVMTLTFENGSKIVINRQEPLHQVWLATKAGGYHFNYRDGHWYCSRSGEEFFAKLSEAATTQAGEEVSFSE
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: MEP1_TRIRU
Sequence: MHGLLLAAGLLSLPLHVLAHPQPSTSTSLAGRAGAVDLNEFRIAHRSSYTSHDEMKKLPSIASFRQGTYLEVATELVKQTMPNMEFRLVDDHYVGDSGIGHVRFRQTMHGIDIDNSDFNVNVGKDGKVLSHGNSFYTGPAPSSNPMVKRDFIDPMQALHGVRKALNLPIKADGAHVEDMSEHKVMFKGTSGALSDPTAKLCYMAKEDGSLALTWRVETDIGDNWLLSYMDAKESSKVHNVVDYVAHATFQVYKWGLADPTEGKREIITNPWNLKTSPLTWLSDGHNNYTATRGNNAIAQYNPDGGNDYENNYRPSPKNLKFEYPYSPDMNPPKTYIDASVTELFYTSNICHDLYYMLGFNEKAGNFQVNNRGQGGKGNDFVILNAQDGSGTNNANFATPPDGQPGRMRAYIWTRANPPRDASFEAGTIIHEYTHGLSNRLCGGPANSRCLNALESGGMGEGWGDFYATAVRLKPNDTRKTNYVKGGWVNNSPKGVRMYPYSTDMNVNPLVYTSNNKLNEVHAIGTVWCTMLYEVLWNLIDKHGKNDGPVPIFENGVPNDGKYLAMKIVMDGMAIQPCNPNFVQARDAILDADMNLTKGANKCEIWKGFAKRGLGVGAKFDPKNRTGSTQVPNECK
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 1, Fungalysin MEP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL16_BUCAI
Sequence: MLQPKRTKFRKMHKGRNRGLASGTDINFGTFGLQAIDRGRLTARQIESARRAITRCIKRQGKMWIRIFPDKPITQKPLEVRMGKGKGNVEYWVALVQPGKILYELEGVTEEESRAAFKLAAAKLPIKTTFVNKMVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HBB_LYNLY
Sequence: GFLTAEEKGLVNGLWGKVNVDEVGGEALGRLLVVYPWTQRFFQSFGDLSSADAIMGNSKVKAHGKKVLNSFSDGLKNIDDLKGAFAKLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGHEFNPQVQAAFQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TRMD_STRPC
Sequence: MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKARHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEELIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTIVDATVRLIPQVLGKESSHQDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLLERYDFSEEERKLLDKIKEALG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTB_PSEAB
Sequence: MNAHEVNFDGLVGPTHNYGGLSYGNVASQSNSQAVSNPKEAAKQGLAKMKALMEMGFKQGVLAPQARPDTAALRSLGFSGSDEEVIRRAAKEAMPLLAACSSASSMWTANAATVSPSADTADGRVHFTAANLNCKFHRSIEHPTTSRVLAAMFNDERYFAHHAALPAVSQFGDEGAANHTRFCKDYGDAGVEFFVFGRSAFDSRFPAPQRYPARQTLEACQAVARLHGLSEAGVVYAQQNPAVIDQGVFHNDVISVGNGEVLFHHEDAFLDTEKVLAELHDKLGRRGGRFRAICVPRDQVAVEDAVKSYLFNSQLLSKADGSMLLVVPEECRNNPRVWNYLDQLTGDDGPIREVKVFDLKQSMQNGGGPACLRLRVALQERELAAVNPGVIMSAGLYDTLVAWVDRHYRDRLSETDLADPQLLLECRTALDELTQILKLGSVYSFQLD
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: HMR1_PONPY
Sequence: MGELMAFLLPLIIVLMVKHSNSRTHSLRYFRLGVSDPIRGVPEFISVGYVDSHPITTYDSVTQQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKRAWEANQHELQYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTTLFCKAHGFYPPEIYMTWMKNGEEIVQEMDYGDILPSGDGTYQTWASFELDPQSSNLYSCHVEHCGVHMVLQVPQESEAIPLVMKAVSGSIVFVIVLTGVGVLVWRRRPREQNGAVYLPTPD
What is the function of this protein?
Antigen-presenting molecule specialized in displaying microbial pyrimidine-based metabolites to alpha-beta T cell receptors (TCR) on innate-type mucosal-associated invariant T (MAIT) cells.  In complex with B2M preferentially presents riboflavin-derived metabolites to semi-invariant TCRs on MAIT cells, guiding immune surveillance of the microbial metabolome at mucosal epithelial barriers (By similarity).  Signature pyrimidine-based microbial antigens are generated via non-enzymatic condensation of metabolite intermediates of the riboflavin pathway with by-products arising from other metabolic pathways such as glycolysis.  Typical potent antigenic metabolites are 5-(2-oxoethylideneamino)-6-D-ribitylaminouracil (5-OE-RU) and 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil (5-OP-RU), products of condensation of 5-amino-6-D-ribityaminouracil (5-A-RU) with glyoxal or methylglyoxal by-products, respectively (By similarity).  May present microbial antigens to various MAIT cell subsets, providing for unique recognition of diverse microbes, including pathogens that do not synthesize riboflavin.  Upon antigen recognition, elicits rapid innate-type MAIT cell activation to eliminate pathogenic microbes by directly killing infected cells (By similarity).  During T cell development, drives thymic selection and post-thymic terminal differentiation of MAIT cells in a process dependent on commensal microflora (By similarity).  Acts as an immune sensor of cancer cell metabolome.  May present a tumor-specific or -associated metabolite essential for cancer cell survival to a pan-cancer TCR on a non-MAIT CD8-positive T cell clone, triggering T cell-mediated killing of a wide range of cancer cell types (By similarity).
What are the official names of this protein?
Major histocompatibility complex class I-related gene protein, MHC class I-related gene protein.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single- pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Note=In the absence of antigen remains within the endoplasmic reticulum where it acts as a metabolite sensor. Antigen binding triggers trafficking of the ternary complex to the plasma membrane. After presentation, most of these complexes are rapidly internalized and degraded via endocytosis. A small subset recycles via endosomes back to the plasma membrane and may thus acquire and present new antigens that do not efficiently reach the endoplasmic reticulum.
Protein: MNME_CLOB1
Sequence: MKEFDTIAAVATPVGEGGISIIRISGDKSLDIVSSIFKGKNDRTLDDIKPYSMRYGFIIEKESKEMIDEVLVSYMKGPRSFTAEDTLEINCHGGVIPTKKILKELIKSGARLAEPGEFTKRAFLNGRIDLSQAEAVIDIIRSKTDLSMKSALKQAEGTLSKEINSIRNRMIKIIAHIEATVDYPEDDLEEITGQKIKVDLKEIINKIDNLISASEEGKILREGLNTVIVGKPNVGKSSLLNALINENKAIVTEIPGTTRDVIEEYINIDGIPIKIVDTAGIRETEDVVEKIGVEKSKEKIDEADLVIFMLDLSRKIDEEDIEIMDFIKNKKYIVLLNKLDLNKDLNEENHFIKELDSKYIIKTSVKNNSGLNELKECIKNLFFSGEIKSDELIVTNARHQEALIRSRESCIQAIETLSDEISIDLASIDIRNAWKYLGEITGDTLDENIIDKIFSEFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.