PharMolix/UniProtQA huggingface dataset:
Protein: KDSA_RHOPA
Sequence: MNKSIAPATSVVAGNVKFGNALPLSVIAGPCQLESRAHALEVASALKEIATRLGIGLVYKTSFDKANRTSAASARGLGLDAALPIFAEIRDHLGLPVLTDVHENEQCARAAEAVDILQIPAFLCRQTDLLLAAAATGRIVNVKKGQFLAPWDMGNVVSKITHAGNSKVLVTERGVSFGYNTLVSDMRALPIMAKTTGAPVIFDATHSVQQPGGKGTSSGGEREYVPVLARAAVAVGVAGVFIETHPDPDHAPSDGPNMVPLREFEALIKTLMEFDALAKKRSTVGAV
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_AERS4
Sequence: MLKRDMTIANYDPQLWQAITDETRRQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPAKRYYGGCEYVDVVETLAIERAKELFGATYANVQPHSGSQANSAVYMALLQPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIIPYGIDESGKIDYDEMERLAVEHKPKMMIGGFSAYSGIVDWARMREIADKIGAWLFVDMAHVAGLIAAGVYPNPVPHAHVVTSTTHKTLAGPRGGLILSAADDEDLYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEALEPEFKTYQAQVVKNAKAMAATFIERGYKIVSGGTDNHLMLVDLIGRELTGKEADAALGKANITVNKNSVPNDPRSPFVTSGVRIGTPAITRRGFKEAESIHLTNWICDVLDNHDNDEVLANTREKVLDICRRFPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIB_SALTY
Sequence: MTILAWCIAWVLDFIIGDPQHWPHPVRWIGRLITFVQRIVRRYCPGDKALRIGGGVMWVVVVGATWGVAWGVLALAQRIHPWFGWSVEVWMIFTTLAGRSLAHAAQEVERPLRKNDLAESRIKLSWIVGRDTSQLQPAQINRAVVETVAENTVDGIIAPLFFLFLGGAPLAMAYKAVNTLDSMVGYKHEKYRAIGMVSARMDDVANYLPARLSWLLLGIAAGLCRLSGWRALRIGWRDRYNHSSPNCAWSEACVAGALGIQLGGPNNYFGERVDKPWIGDAQRDISVDDISRTIRLMWVASTLALALLIAARCGLSGVA
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.  However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate.
What are the official names of this protein?
Cobalamin biosynthesis protein CbiB.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRBK_RHIRD
Sequence: MSSRLIVILALLAVVAAASAGIGTWITVQPEPASGSGAAATDTPSSEERRRHRDQFFGGDSNREIRGGQEMKPRW
What are the official names of this protein?
Conjugal transfer protein TrbK.
Protein: RS6_ECOLC
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: STIP1_RAT
Sequence: MEQVNELKEKGNKALSAGNIDDALQCYSEAIKLDPQNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQLKEGLQNMEARLAERKFMNPFNLPNLYQKLENDPRTRTLLSDPTYRELIEQLQNKPSDLGTKLQDPRVMTTLSVLLGVDLGSMDEEEEAATPPPPPPPKKEAKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDKALKHYDKAKELDPTNMTYITNQAAVHFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEERYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLIAIR
What is the function of this protein?
Acts as a co-chaperone for HSP90AA1 (By similarity).  Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90 (PubMed:9528774).
What are the official names of this protein?
Stress-induced-phosphoprotein 1, STI1, Hsc70/Hsp90-organizing protein, Hop.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Dynein axonemal particle.
Protein: MINE_NEIMA
Sequence: MSLIEFLFGRKQKTATVARDRLQIIIAQERAQEGQTPDYLPTLRKELMEVLSKYVNVSLDNIRISQEKQDGMDVLELNITLPEQKKV
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity).
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: PHC3_HUMAN
Sequence: MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARINSLKES
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
What are the official names of this protein?
Polyhomeotic-like protein 3, Early development regulatory protein 3, Homolog of polyhomeotic 3, hPH3.
Protein: NEBL_MOUSE
Sequence: MKVPVSGDVKEETEEENVEQEENQEAKVSLKPVIEDLSMELARKCTELISDIHYKEEYKKSKDKCTFVTDTPMLNHVKNIGAFISEAKYKGTIKADLSNCLYKDMPATIDSVFAREVSQLQSEVAYKQKHEAEKGFSDYTHMKEPPEVRRAMEVNRHQSNISYRKDMQGTHTYTAELDRPDIKKATQISKIISDAEYKKGQGIVNKEPSVIGRPDFEHAVGASKLSSQVKYKEKFDNEMKEKSHHYNPLGSAFFRQHQFAAVLASDWEYKRDFEENKGLYHFDAEAPEHLHHKGNATLQSQVKYREEYEKNKGKSMLEFVETPSYQSSKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPAFLHVKHITNLMREKEYKKDLENEIKGKGMELSSEVLDIQRAKRASEMASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKRASEMASQVRMV
What is the function of this protein?
Binds to actin and plays an important role in the assembly of the Z-disk.  May functionally link sarcomeric actin to the desmin intermediate filaments in the heart muscle sarcomeres.  Isoform 2 might play a role in the assembly of focal adhesion (By similarity).
What are the official names of this protein?
Nebulette, Actin-binding Z-disk protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOLR_RALSL
Sequence: MEPDFQDAYHAFRTAEDEHQLFREIAAIARQLGFDYCCYGARMPLPVSKPAVAIFDTYPAGWMQHYQASGFLDIDPTVRAGASSSDLIVWPVSIRDDAARLWSDARDAGLNIGVARSSWTAHGAFGLLTLARHADPLTAAELGQLSIATHWLANLAHTLMSPFLVPQLVPESNAVLTTREREVLCWTGEGKTAYEIGQILRISERTVNFHVNNVLLKLAATNKVQAVVKAIATGLI
What are the official names of this protein?
Transcriptional activator protein SolR.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-regulated transcriptional regulatory protein family.
Protein: ZDH24_MOUSE
Sequence: MGESWAARGAEGAPARMPLVLTALWAAVVVLELAYVMVLGPGPPPLGPLARALQLALAAYQLLNLLGNVVLFLRSDPSIRGVMLAGRGLGQGWAYCYQCQSQVPPRSGHCSACRVCILRRDHHCRLLGCCVGFHNYRPFLCLLLHSAGVLLHISVLLGPALSALLQAHSALYTVALLLLPWLMLLTGKVSLAQFALAFVVDTCVAGALLCGAGLLFHGMLLLRGQTTWEWARGHHCYDLGTCHNLQAALGPRWALVWFWPFLASPLPGDGISFQTPGDVGLVTS
What is the function of this protein?
Probable palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates.
What are the official names of this protein?
Probable palmitoyltransferase ZDHHC24, Zinc finger DHHC domain-containing protein 24.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HAUS5_MOUSE
Sequence: MELTQKERELSRWAAEEMEVPLAARPRESTLRRLCLSQGADIWAYIVQHVRSQRNIKKIQGNLLWHAYQDNPKIHRKLELEATVARLRAENQELDQSLELMDQESEAQDVAMTQTLQSLKDTQHRALLLQAQAGAVRRQQRGLQDPMQRLQNQLKHLQDMQRKAKVDVTFGPVVSAAPALEPEVLGDVRAACTLRTQFLQNLLTPRARGGSILSPCDDHVGTSYQQWLTSVETLLTNHPAGHVLAALEYLAAERESEIRSLCYGDGLKEEELSRPQAPESSNSSQVLPSTVHLIQEGWQAVGALVTQRSALLSERQVLTGRLQRLVEEVKRLLLGSSERKVLLLGLRHSGLLAELKALHAQSQELESAVGQRHLLLRELQAKRQRILQWRQLVEDRQEQIRLLIKGNSASKTRLSRGPEEVLALIDQKLVPTSEAVAPQSQELLRCLKEEAKHLPRVLLGPLLPYHVKGLKPLSRILPSIHQLHPTNPRASSLILLSHTLGLPVGKASELLLPRAASLQQDLLFLQDQLGLRRGNLCVKTSLPPGPSTQELLQMQVSQEKEQNENVGQTLKKLSNLLKQALEQIPELQGIVQDWWEQPSQAALPEEICQGLSLPQCQLR
What is the function of this protein?
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
What are the official names of this protein?
HAUS augmin-like complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the HAUS5 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules.
Protein: CH602_SACEN
Sequence: MAKQIAFDEQARRALERGVNQLADAVKVTLGPRGRHVVLDKQFGGPQVTNDGVTIAREIELEDPYENLGAQLAKNVATKTNDVAGDGTTTATVLAQAMVREGLRNLAAGANPTALGRGIQAATDAVVDALKAKATPVKGRDNIAQIATVSSRDESIGALVGEAMERVGEDGVISIEESSTLATELEITEGVQFDKGFVSPYFVTDSERQEAVLEDAQILLHREKISSIQDLLPLLEKIAQSGKPLLILAEDVEGEALSTLVVNAIRKTFKVVAVKAPYFGDRRKAFLDDLAAVTGAQVIAPEVGLKLSEAGPEVLGSARRITVTKDTTTIVDGRGPQDDVKARAEQIRKEIEVSDSDWDREKLQERLAKLAGGVAVIKVGAATETELKERKSRIEDAVAASKAAAEEGSVPGGGSSLIHAAKELNGDLGLSGDEATGVRLVRTALEAPLFWIASNAGQEGAVVVSKVRDLDWGQGYNAATLTFGDLVQPGIVDPLKVTRSAVANAASIARMVLTTESAVVDKPEEEDSAAAGHGHGHSH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCL2_YEAS7
Sequence: MSQSRWSIVLIFALFIFGSTGVNAFFNFGHHQQQQQQQQQSYEDQVLNNPCDGYLCPDTLTCVAQQKDCPCPFPKSQLKCVLPDNKFVCISKPATHNEKFRAIYDDPVKGPKAKNKGFRDCGWVSDAYKNH
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: MP83_MYCBT
Sequence: MINVQAKPAAAASLAAIAIAFLAGCSSTKPVSQDTSPKPATSPAAPVTTAAMADPAADLIGRGCAQYAAQNPTGPGSVAGMAQDPVATAASNNPMLSTLTSALSGKLNPDVNLVDTLNGGEYTVFAPTNAAFDKLPAATIDQLKTDAKLLSSILTYHVIAGQASPSRIDGTHQTLQGADLTVIGARDDLMVNNAGLVCGGVHTANATVYMIDTVLMPPAQ
What are the official names of this protein?
Cell surface glycolipoprotein MPB83, Lipoprotein p23.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Secreted, cell wall. Secreted.
Protein: PLCX1_HUMAN
Sequence: MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISHEESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHFVHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLCPRGEVPTLRQLWSRGQQVIVSYEDESSLRRHHELWPGVPYWWGNRVKTEALIRYLETMKSCGRPGGLFVAGINLTENLQYVLAHPSESLEKMTLPNLPRLSAWVREQCPGPGSRCTNIIAGDFIGADGFVSDVIALNQKLLWC
What are the official names of this protein?
PI-PLC X domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_PICTO
Sequence: MSERILVNCALPYANGPLHLGHIAGAYLAADIFVRFNRLNGNEVLFVSGSDEYGTPITITAEKNKTSPQNVADIYHREHEQTFKNLDIVFDIFTRTTDPEHVKDVDEFFINLLNKNYLEKRYMVSPYCKSTGKFMPDRYIHGTCPYCGFNDARGDQCDECGRTLDPIELINPRCTSSNEEPLFIATEHFFLRLDLLSDELLNYLNTRENWKPNVINFTRSIINEGLRPRPITRDIDWGVPIPLNGFEGKRIYVWFEALIGYITGARVYSKNIKDDDYWKKFWLDKNVKSYYFIGKDNIPFHTIIWPAMLIAHGDYNLPYNVPANEYLRFEGAQFSKSRGIGYTVNEALSLVNKNYLRYYMASIMPETGDSSFSLNELVSRVNSELIDKYGNFIYRVLGFISNRKINIKKCEPDSIINEFKRFFDEYSESIKNIKIKNGLQIWLEAVTLANNYFNSEAPWNINDHERLNQVLFTSLKISMYLTAMLYPYVPSASSEILSSLGFKTVNYKFDDMLGFDDFRPLKGEPPFKKLEIADKKINIDLMVGTVKYVNDHPNADNLYVLGVHADRDITIVSNIKKYLTPENLQGRRILLIRNVKPATIRGIKSEAIIIAVQHGERIIIPEVNADDGSRMKIDGFDFNGDIISMDEIKRYKFIVDKNELVLEYNNSRFIITENGKPLKINAPDGSSIVL
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECC1B_MYCTO
Sequence: MTAEPEVRTLREVVLDQLGTAESRAYKMWLPPLTNPVPLNELIARDRRQPLRFALGIMDEPRRHLQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTMVMSAAATHSPRNVQFYCIDLGGGGLIYLENLPHVGGVANRSEPDKVNRVVAEMQAVMRQRETTFKEHRVGSIGMYRQLRDDPSQPVASDPYGDVFLIIDGWPGFVGEFPDLEGQVQDLAAQGLAFGVHVIISTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDRITREIPANRPGRAVSMEKHHLMIGVPRFDGVHSADNLVEAITAGVTQIASQHTEQAPPVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAHCHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGLLDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSRSWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQMSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSSEFKVKRRPPGQAFLVSPDGKEVIQAPYIEPPEEVFAAPPSAG
What is the function of this protein?
Part of the ESX-1 specialized secretion system, which delivers several virulence factors to host cells during infection, including the key virulence factors EsxA (ESAT-6) and EsxB (CFP-10).  EccCb1 may link the cytosolic components of the system with the membrane components.
What are the official names of this protein?
ESX-1 secretion system protein EccCb1, ESX conserved component Cb1, Type VII secretion system protein EccCb1, T7SS protein EccCb1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_LACP3
Sequence: MASAHIEHKLSLLPDLPGSYQMKDINGKIIYVGKAKNLKNRVRSYFKSSHDGKVAAMVSQVADFDFIVTSTDKEAFLLEITLIQKYQPYYNIKLKKGTGYPYIKITHERDPKIEITGTIRKDGGYYFGPYPNVYAAQETMHFIQKVYPLRRCNGYQGRPCLYYHMGQCLGACFRTVPEKEYTDQIERIKRFLNGNVGKAKASLTAKMERAAKNLQFERAAEIRDQLHYIEQTLEKQKIISHDNTTRDLFNFYMDKGWISIQVFFIRQARLMKRESRLFPVVNTAKEEFESFILQFYSRRNNVKPREVLVPAGLDNKVLADILEIPVRTPQRGEKRDLMALAAKNSQIKLEDKFRLMELDNRTTIGAMKELMAALNLPMGHVAEAFDHSHIQGADPVSAMVQFVDGQPAKNNYRKYKLDADKTHNGADEAANTREVIRRRYTRLLKERAPLPDLILMDGGEIEMNAAKDVLENELNLDIPVAGMVKNNKHKTAALLFGNADQLINLDPKSQGFYLLERIQDEVHRFAITFHRQLHAKNSLASRLEGIKGVGPKTRLKLLRKFKTINKIKEAPLEDIQELGISKKVAQALKLSLTAEPTPARRV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_PSEAE
Sequence: MDMQHRIRQLFQASIETKQQALEVLPPYIEQASLVMVNALLNEGKILSCGNGGSAGDAQHFSSELLNRFERERPSLPAVALTTDSSTITSIANDYSYNEVFSKQIRALGQPGDVLLAISTSGNSANVIQAIQAAHDREMLVVALTGRDGGGMASLLLPEDVEIRVPSKITARIQEVHLLAIHCLCDLIDRQLFGSEE
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_GEOKA
Sequence: MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGNNAGHTIVFNGEKYKLHLIPSGIFYKDKICVIGNGMVVDPKALVAELSYLHERGISTDNLRISNRAHVILPYHLKLDELEEERKGANKIGTTKKGIGPAYMDKAARIGIRIVDLLDRDVFAEKLERNLREKNTLLEKVYGVEGFRLEDIFEEYYEYGQHIAKYVCDTSVVLNNALDEGRRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGAGVGPTKIKHVVGVAKAYTTRVGDGPFPTELHDEIGDRIREVGREYGTTTGRPRRVGWFDSVVVRHARRVSGITDLSLNSIDVLTGIETLKICVAYRYRGQVLEEFPASLKVLAECEPIYEELPGWTEDITGVKSLDELPANARHYVERISQLTGIPLSIFSVGPDRSQTNVVRSVYA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHO1_CHAGB
Sequence: MEYSRPQYGRKRMSLGNIIGDPFALATTSIATLAWLISFVATIIAHIQYPVKFPLFAYWALVFYFGLIIGVFVVVASDSTQTYHVALVGYLGCGLVLSTSSVNNLIHDNQGAKEASAAGFILLSMVTIVWIFYFGSAPSAVPRAYIDSFALAKESTSTNRQTMTGGYGGRRPETSTSVQPPQMYTAQLNGLENPSPVGGMTSAMTNPTIPPAYTAPPTQKTAAPNAENPNAEIVPPTEYPYRAKAIYSYEANPEDANEISFSKHEILEVSDVSGRWWQARKESGETGIAPSNYLILL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HINT3_MOUSE
Sequence: MAEKQAGLVGEPDPEGSSPGTSESWNYDSNCVFCRVAAGQEPKTELFHCENEDLVCFKDIKPAALYHYLVVPKKHIGSCKDLNKDHIEMVESMVAAGKTMLERNNFTDFTDVRMGFHVPPFCSISHLHLHVIAPVKEFGFLSKLVYRQDSYWFVTVDYLLEKLRK
What is the function of this protein?
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (By similarity).  Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase (By similarity).
What are the official names of this protein?
Adenosine 5'-monophosphoramidase HINT3, HINT-4, Histidine triad nucleotide-binding protein 3, HINT-3.
What is the protein family that this protein belongs to?
Belongs to the HINT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CST9L_HUMAN
Sequence: MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTFTCFFTISTRPWMTQFSLLNKTCLEGFH
What are the official names of this protein?
Cystatin-9-like, Testatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_COXBU
Sequence: MIMRPSKRAANELRPLSFTTQFTRYAEGSVLVTLGNTKVICNASIVEGVPRFLKNSEQGWLTAEYGMLPRSTHSRMDREASRGKQGGRTVEIQRLIGRSLRAALDLKLLGPYTITIDCDVIQADGGTRTAAINGSCIAMIEALRHLQRKGILQTDPLKHKVAAVSVGIYKGVPVLDLDYAEDSNAHTDMNVVMTDNDAFIEIQGTAEGDAFHAKELDALINLARHGIKQIIEKQQEALS
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: Y745_HELPY
Sequence: MQKVFIALTDHKRLDEFLAKELQISKNQVLNLIKEGLVFCQKKEVKKGGLALKEGDEITLLTPKITPKPLKKELDLEIEVIFEDEDLLVLNKPPNLVVHKALSVKEPTLVDWLEFKNYELSNLGLKERYGIVHRLDKDTSGGIVIAKNNFTHVHLSEQLKTKMMGRYYIALLSTPLKEEKMSVECYLTRNPNNRLKMIALKAVKKEKSRYSKSEFISLLTSQNNLNLIGAKLFTGRTHQIRAHLEYLNRHIIGDNLYGLNGALPKEEIRIMLHAYLIEFKHPRSEQKLRFKVPLLKDMLEYLKKVFDKENLDEVLDEEKILHAFIAK
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase HP_0745, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: RPOB_ARATH
Sequence: MLGDEKEGTSAIPGFNQIQFEGFYRFIDQGLIEELAKFPKIEDIDHEIEFQLFVETYQLVEPLIKERDAVYESLTYSSELYVSAGLIWKTSRNMQEQRIFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYQSELDHNGISVYTGTIISDWGGRLELEIDKKARIWARVSRKQKISILVLSSAMGLNLREILENVCYPEIFLSFLTDKEKKKIGSKENAILEFYQQFSCVGGDPIFSESLCKELQKKFFHQRCELGRIGRRNINWRLNLNIPQNNIFLLPRDVLAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQLGLALARLENVVKGTISGAIRHKLIPTPQNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTANFRIRDIHPSHYGRICPIDTSEGINVGLIGSLSIHARIGDWGSLESPFYELFEKSKKARIRMLFLSPSQDEYYMIAAGNSLALNRGIQEEQAVPARYRQEFLTIAWEEVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQVALDSGVPAIAEHEGKILYTDTEKIVFSGNGDTLSIPLIMYQRSNKNTCMHQKPQVRRGKCIKKGQILADGAATVGGELALGKNILVAYMPWEGYNFEDAVLISECLVYGDIYTSFHIRKYEIQTHVTTQGPERITKEIPHLEGRLLRNLDKNGIVMLGSWVETGDILVGKLTPQVAKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWVQKKGGSSYNPEIIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFECSLGLAGSLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRSKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPKPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKEV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: THIC_ACIAD
Sequence: MNQLTNLSPADLSAQHEQDAKDLTRILPASTKVYIQGSRPDIQVPMRQIALTDTPTGLGGEKNPPVMVYDTSGVYTDPEVAIDLNKGLPHVRQAWIEERQDTDVLDTLSSSFGQERLKDIRTADIRFAHIQKPRRAKTGQNVTQMHYAKKGMITPEMEYIAIRENQRQRDEVDMRQHAGQNFGAKNLTEITPEFVRQEVAAGRAIIPANINHPEIEPMIIGRNFLVKINANIGNSALGSSIDEEVSKMTWATRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGVAEDLTWEIFKDTLIEQAEQGVDYFTIHAGVLLRYVPLTANRLTGIVSRGGSIMAQWCLAHHEENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIQDANDEAQFGELRTLGELTHRAWEHDVQVMIEGPGHVPMHMIKENMDLQLEVCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFNLSLDPDTARSMHDETLPKEAHKSAHFCSMCGPKFCSMKITQNVRNYAQNQETAKDFNPSTEEVEQGLKSMKQAYHDNGQKLYQKV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.