PharMolix/UniProtQA huggingface dataset:
Protein: NUOB_CHLPB
Sequence: MGLLDAKISNHNVLVTSVDNVLNWARLSSLWPMGFGLACCAIEMMATNASNYDLERFGIFPRSSPRQSDLMIVAGTVTMKMAERVIRLYEQMPEPRYVLSMGSCSNCGGPYWKHGYHVLKGVDRIIPVDVYVPGCPPRPEALIGGLMKVQELIRMEQIGISRVEALKKLEEKNIDPGQLIEDARKGAMAS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FABV_TOLAT
Sequence: MIIAPKVRGFICTTTHPAGCEANVRQQIAYVKSKGPLANGPKRVLVIGASTGYGLASRITAAFGSDAATIGVFLEKAGTEKKPGSAGWYNSAAFDKAAKEAGLYSKSVNGDAFSDECRAKVVELIKADLGQVDMVVYSLASPVRKLPATGELIRSALKPIGEVYTATAVDTNKDELIEAHVEPANEEEIANTIKVMGGEDWELWLQALDQAGVLAEGVKTVAYSYIGTDITWPIYWHGTLGRAKEDLDRASSAIRQQLSSKNGTANVAVLKSVVTQASAAIPVMPLYIAMSFKLMKEQGIHEGCIEQIQRMFYTRLFDGEFVTDDAQRIRMDDWELRESVQQACRDLWPQVTTENLSQLTDYQGYKAEFLKLFGFGWEGVDYTADVNPEVNFDVVAM
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: PDE6B_CANLF
Sequence: MSLSEEQVQHFLDQNPDFTDQYFGKTLSPEHVAGACGDGQPTDCASFRELCQVEESAALFELVQDMQESVNMERVVFKILRRLCTILRADRCSLFMYRQRNGVAELATRLFSVQPGSALEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVQDVTECPHFSPFADELTGYETRNILATPIMNGKDVVAVIMALNKLDGPCFTSEDEDVFLKYLNFGTLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQPYSGPRTPDGREIVFYKVIDYILHGKEDIKVIPSPPADHWALASGLPTYVAESGFICNIMNTAADEMFTFQEGPLDDSGWVIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDEVLMESLTQFLGWSVLNTDTYDKMNKLENRKDIAQDMVLYHVRCDKDEIQLILPTRERLGKEPADCEEDELGILLKEVLPGPSKFDIYEFHFSDLECTELELVKCGIQMYYELGVVRKFQIPQEVLVRFLFSVSKGYRRITYHNWRHGFNVAQTMFTLLTTGKLKSYYTDLEAFAMVTAGLCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKFLLSEETLNIYQNLNRRQHEHVIHLMDIAIIATDLALYFKKRTMFQKIVDESKNYEDRKSWVEYLSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLDQQPIPMMDRNKAAELPKLQVGFIDFVCTFVYKEFSRFHEEILPMFDRLQNNRKEWKALADEYEAKLKALEEEKQQQEDRTTAKKAGTEICNGGPAPKSSTCCIL
What is the function of this protein?
Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP (PubMed:8387203).  Necessary for the formation of a functional phosphodiesterase holoenzyme (By similarity).  Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock (By similarity).  May participate in processes of transmission and amplification of the visual signal (By similarity).
What are the official names of this protein?
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, GMP-PDE beta.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Cell projection, cilium, photoreceptor outer segment.
Protein: ATP6_LEGPC
Sequence: MGEEGFLAHFAFSIGGLPITQSVLTTWFIMISLFIMAWSTTYKCSLLQPSTYQLLWEGVLSTMYDAIKEVLPDHVELIFPFVATLWIFILVSNLIGVIPGFYSPTADLSVTASLAMMTFLSVHWFGIRAEGWREYLKHYIKPTPFLLPFHLISEISRTLALAVRLFGNIMSLQLTALIVLMIAGFLVPIPILILHIIEAIIQAYIFGMLALIYIAGGIQAHELKSQGESL
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DHB12_MOUSE
Sequence: MECAPPAAGFLYWVGASTIAYLALRASYSLFRAFQVWCVGNEALVGPRLGEWAVVTGGTDGIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYDKIKTGLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERSKGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLVATKLAKIQKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHSLMGSINSIMPRWMYFKIIMGFSKSLRNRYLKKRKKN
What is the function of this protein?
Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation.  Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 17-beta-hydroxysteroid dehydrogenase 12, 17-beta-HSD 12, 3-ketoacyl-CoA reductase, KAR, Estradiol 17-beta-dehydrogenase 12, KIK-I.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GLO2_BUCBP
Sequence: MKIIFTKVLFDNYVWIMFNSSKDCIIIDPGESNSVIKKIKKLNLNPKIILLTHNHLDHIQGVKNLLYKYPEISIYGPLETQFCGTKNLIDNRNTIEILNTKFYIIPTPGHTNGHTAYYCPPFLFCGDSIFSGGCGRVKNGMMIKMYNSLRTISKLPNDTLIYCSHEYTRSNLEFFKKIFPKNLNILNYYNNIKKSKTQCTLPSTLKIEKKINPFLQLNNTNLRHQVKIHNDLSFSLNFFIYLRKIKDKS
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: Y027_RICPR
Sequence: MDFITNRKFRSTLLCHQNIPINRKIEFENLKDFYTTFNIRPISSENKIDLNNEQENISFYYENLPEPFISTTSAIMKAILYVYAENISNPIRLEQVAKEAFKKLGKYQLQDFLAILEQHFITFIFQGYLKIFETKPHAIATITEKPKTSQFVRYQAKHAHFNNVTNMLSVTNRLNDMIGIPIHEKYILEMLDGTHNIDDIKKGMIEKINSKLLIACDNKGQAVTDPKLLKEFVDYIVNISLEKFRINYLLIG
What are the official names of this protein?
Uncharacterized protein RP027.
Protein: QCRA_MYCTO
Sequence: MSRADDDAVGVPPTCGGRSDEEERRIVPGPNPQDGAKDGAKATAVPREPDEAALAAMSNQELLALGGKLDGVRIAYKEPRWPVEGTKAEKRAERSVAVWLLLGGVFGLALLLIFLFWPWEFKAADGESDFIYSLTTPLYGLTFGLSILSIAIGAVLYQKRFIPEEISIQERHDGASREIDRKTVVANLTDAFEGSTIRRRKLIGLSFGVGMGAFGLGTLVAFAGGLIKNPWKPVVPTAEGKKAVLWTSGWTPRYQGETIYLARATGTEDGPPFIKMRPEDMDAGGMETVFPWRESDGDGTTVESHHKLQEIAMGIRNPVMLIRIKPSDLGRVVKRKGQESFNFGEFFAFTKVCSHLGCPSSLYEQQSYRILCPCHQSQFDALHFAKPIFGPAARALAQLPITIDTDGYLVANGDFVEPVGPAFWERTTT
What is the function of this protein?
Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
What are the official names of this protein?
Cytochrome bc1 complex Rieske iron-sulfur subunit, Cytochrome bc1 reductase complex subunit QcrA, Rieske iron-sulfur protein, Ubiquinol--cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOA_FERNB
Sequence: MIQITGRKFKLEEQVEHEDHYYARYSLSPLEKGYAVTVGNTLRRVLLSSIPSFAITDVRFVKPEKYHEFDTIEGAKEDIMDILLNLKKVQLRVDTYVESPVKLTINKKGPGVLTAGDIECPAGVVVVNPGHYLATLNEDADLEIELYATFGKGFVPAADRNERPEIGWIVLDGVYSPVIKVNWLVENVRVDKRTDYEKLILEIWTKKSIKPSEALKHSLKIILDHFMFIEQSLSDVEELPIPIIQETAVVTEEIGSPEDVMSKKVEELELSARSLNCLKRDKIETIGDLLSRTEEELMKIKNFGLKSLEEVREKLRDKFGLSLRKGDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: REX_THEP3
Sequence: MSKKTKVSMAVIRRLPRYHRYLEELLKNDVKRISSRELSEKMGVTASQIRQDLNNFGGFGQQGYGYNVEELYNNLTKILGLDKTYNTIIIGAGNLGQAIANYTSFEKSGFNLKGIFDINPRLFGLKIRDVEVMDIETVEDFIARNKIDIGILCIPKDNAQYTADRLVRAGIKAIWNFSPIDLKVPDDVILENVHLSDSLFTVSYRLNEEELFKKLKGETAKIDG
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2734_YERPY
Sequence: MNINVANLLNGNYILLLFVVLALGLCLGKLRLGSIQLGNAIGVLVVSLLLGQQHFAINTEALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSAMILALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHTMANGSSLQQAQDNLSLGYALTYLIGLVSLILGARYLPKLQHQDLPTSAQQIARERGLDTDSQRKVYLPVIRAYRVGPELVAWADGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQVGDEISLVGYPDAHSRLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNSNAVGKRLSHLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKSVAEKIGFISIHSQVTDLLAFCSFFILGLMIGLITFQFSNFSFGIGNAAGLLLAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGGGINSSLGAVGGQMLISGLIVSLVPVVICFVFGAYVLRMNRALLFGAIMGARTCAPAMDIISDTARSNIPALGYAGTYAIANVLLTLAGSLIVILWPGILG
What are the official names of this protein?
Putative transport protein YPK_2734.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NEP1_PYRCJ
Sequence: MILVLAEAALELVPESLWRHPAIVADARRRGKKPGEILLDRARHHVAMAKLDKAERRGRPDIVHQVLLAFQYSLLNRAGRGRAFVHTVGDYIISVKPETRVPKNYNNFVSLMEQLFKVGRVPPEGEALMEARRGSLAALLEELGGKWVALHEQGRAVSFAELGRAVADAVVVVGGFPHGDFENKWILEGAEAVYKIGNVSLDAAQAVCRAVAAAEAALGLI
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: RL14_BRUSI
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRRYASVGDIIVVSIKEAIPRGRVKKGDVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLIDNKKEPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: UBIA_ECO24
Sequence: MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KS71A_ECOLX
Sequence: MSEYMKNEILEFLNRHNGGKTAEIAEALAVTDYQARYYLLLLEKAGMVQRSPLRRGMATYWFLKGEKQAGQSCSSTT
What are the official names of this protein?
P fimbrial regulatory protein KS71A.
Protein: PPIB2_RHIO9
Sequence: MSRFNIATLFITLLVTLCTFRFVSAESKGPVITDKIYFDIKQGEESLGRIVFGLYGKTVPKTAENFKQLATGQNGYGYKGSTFHRVIDQFMIQGGDFTNHDGTGGKSIYGSRFPDENFKLRHTVPGLLSMANAGPDSNGSQFFITTVVTSWLDGKHVVFGKVLEGMDVVTKIEKTPTNYRSKPNVDVVIADCGLLSDDASEEAVKHAEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B2, PPIase B2, Cyclophilin B2, Rotamase B2.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: ENO2_CUPMC
Sequence: MSKVAEIRGLEVLDSRGNPTVEVEVVLDDGAVGRAIVPSGASTGAREAVELRDADPRRYLGRGVLRAVQAVNTELCEALLGRDAGDQPEIDTIMIDLDGTPDKRRLGANALLGVSLAVAHAAAMSNGLPLFAYLGGERASLLPVPLINVINGGAHADNALDFQEFMIVPAGAPTFTEAVRASAEVFHTLRAMLKAAGYTTNVGDEGGFAPEFHAAEEALDILVAAIAKAGYRPGEDIALAIDPAASELYVNGSYVYQGEGVERSREEQVAYLVRLADRYPIVSIEDGMAEDDAMGWQLLTRQLGKRCQLVGDDVFCTHPTLLRQGVEQGMANAILVKANQIGTLSEMRETVRVAHGYAYSAVMSHRSGETEDVTIADLAVALRCGQIKTGSMSRADRTAKYNRLLRIERELGSRAEYAGALLRRR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 2, 2-phospho-D-glycerate hydro-lyase 2, 2-phosphoglycerate dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CLPP_STRPG
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGKTIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC1A_XENLA
Sequence: MGDAEKGKKIFIQKCAQCHTVEKTGKHKTGPNLWGLFGRKTGQAPGFSYTDANKSKGIVWGEDTLFEYLENPKKYIPGTKMIFAGIKKKNERLDLIAYLKKSTSE
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
What are the official names of this protein?
Cytochrome c, somatic A.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: GBRR2_HUMAN
Sequence: MPYFTRLILFLFCLMVLVESRKPKRKRWTGQVEMPKPSHLYKKNLDVTKIRKGKPQQLLRVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVFS
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.  Rho-2 GABA receptor could play a role in retinal neurotransmission.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit rho-2, GABA(A) receptor subunit rho-2, GABA(C) receptor.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: PYRH_SULAC
Sequence: MKLTLKVSGKFFDEENSENLSLLRDVIIDLVNNGHRVAVVTGGGGTARRYISMGRKLNLNESHLDILGILVSRLNAQLLLFSLDNIAYPKVPESIEDFNERWASGKVVITGGFQPGQSTAGVAALVSEIINADYLVLATNVNGVYTKDPQKFVDAKLLPKLTVSELKTILEGSQSVNAGKYELLDPLAIKIVERSKIKVLVINFKDLNKLPNILKGNEILGSVVVPE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADHX_MAIZE
Sequence: MASPTQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRVKILFTALCHTDHYTWSGKDPEGLFPCILGHEAAGIVESVGEGVTDVQPGDHVIPCYQAECKECKFCKSGKTNLCGKVRSATGVGVMMNDMKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKINPQAPLDKVCLLGCGVPTGLGAVWNTAKVESGSVVAVFGLGTVGLAVAEGAKAAGASRVIGIDIDNKKFDVAKNFGVTEFVNPKEHDKPIQQVLVDLTDGGVDYSFECIGNVSIMRAALECSDKGWGTSVIVGVAASGQEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVDKYMKKEIKVDEYITHNMNLADINDAFHLLHEGGCLRCVLAMQI
What are the official names of this protein?
Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH, S-(hydroxymethyl)glutathione dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_CAUVN
Sequence: MTDTTSKTRAGFAAIIGAPNAGKSTLVNRMVGAKVSIVTQKVQTTRFPVRGVAIEGDTQIVLVDTPGIFSPRRRLDRAMVRAAWAGSEEAEATVHLVDVQAELASRADKATPGEYRSAQDVQTIIEGLKAADRKVILALNKIDGIKRDTLLAVAKDFFDTGVYSDVFMISASTGAGVEDLTAKLVSMMPEGPWLYPEDQTADLPARLLAAEITREKVYLRVHEELPYAATVETTAFEERKDGSVRIEQTILVEREGQRVIVIGKGGQTLKWIGQASREELCDILDRKVHLFLHVKVKENWAEERGLFSDIGLDFDV
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: HIS3_METST
Sequence: MIKPNFRHIINGKRLATAIAQDYKTGEILMVAFIDEEAFNKTIQTRKAHYYSTSRNMIWYKGEESGHIQEIKEVLLDCDEDAIIFKVKQVGGACHTGHYSCFYKKLSDDGEVVTEYEDKVFDPEDVYEK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDQ_ECOLI
Sequence: MIRNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATMIGDDETNWGTKSLAILDMPFTAVMDTLLLPWDVFRKDSSVRSRVEKSEANAQATNAVIPPARMPDN
What are the official names of this protein?
Uncharacterized protein YidQ.
What is the protein family that this protein belongs to?
To E.coli YceK.
Protein: PURU_MYCBO
Sequence: MGKGSMTAHATPNEPDYPPPPGGPPPPADIGRLLLRCHDRPGIIAAVSTFLARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQRDFGSTVADKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANHPDLAAHVRPFGVPFIHIPATRDTRTEAEQRQLQLLSGNVDLVVLARYMQILSPGFLEAIGCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTHTVDDLVRVGADVERAVLSRAVLWHCQDRVIVHHNQTIVF
What is the function of this protein?
Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
What are the official names of this protein?
Formyltetrahydrofolate deformylase, Formyl-FH(4) hydrolase.
What is the protein family that this protein belongs to?
Belongs to the PurU family.
Protein: CQ62_CONCB
Sequence: MHTLEMLLLVLLLVPLAPGEGDGQAVGGDRNPSEARRAYKRLLQRPARRMDRGGCTPCGPNLCCSEEFRCGTSTHHQTYGEPACLSY
What are the official names of this protein?
Conotoxin Ca6.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin Q superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR9_BACTN
Sequence: MSESKRIKTALVSVYHKEGLDEIITKLYEEGVEFLSTGGTRQFIESLGYPCKAVEDLTTYPSILGGRVKTLHPKIFGGILCRRDLEQDIQQIEKYEIPEIDLVIVDLYPFEATVASGASEADIIEKIDIGGISLIRAAAKNYNDVIIVASQAQYKPLLDMLMEHGATSSLEERRWMAKEAFAVSSHYDSAIFNYFDAGEGSAFRCSVNNQKQLRYGENPHQKGYFYGNLDAMFDQIHGKEISYNNLLDINAAVDLIDEYEDLTFAILKHNNACGLASRPTVLEAWTDALAGDPVSAFGGVLITNGVIDKAAAEEINKIFFEVIIAPDYDVDALEILGQKKNRIILVRKEAKLPKKQFRALLNGVLVQDKDMNIETVADLRTVTDKAPTPEEVEDLLFANKIVKNSKSNAIVLAKGKQLLASGVGQTSRVDALKQAIEKAKSFGFDLNGAVMASDAFFPFPDCVEIADKEGITAVIQPGGSVKDDLTFAYCNEHGMAMVTTGIRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: YBR2_YEAST
Sequence: MSTYEEEHGIQQNSRDYQEVGGTSQEEQRRQVRSQLQGLFQNFGNTSGEGDAHSDSTLLLRLLSQMLPESLQEEWLQEMDKGKSAGCPDTFAASLPRINKKKLKATDNCSICYTNYLEDEYPLVVELPHCHHKFDLECLSVWLSRSTTCPLCRDNVMGHRIINEIDTTEAELEEDWGMYG
What are the official names of this protein?
Uncharacterized RING finger protein YBR062C.
Protein: PTH_THEP3
Sequence: MYVIAGLGNPGREYEGTRHNVGFMVIDELAKKLGMNVTKLKFKSLVGEGNFKGEKIILLKPQTFVNSSGEALYDAVNFYKIPLENVIVIYDDKDLDVGKIRIRKKGSSGGHNGMNSIIYLLNSEEFPRVRIGIGKPQKDLVSHVLGKFEESEKKLIDEAVIKAADAVIDIIENGIEHAMSKFNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPMC_HAEIN
Sequence: MEHKLEDIIAIFNQCFEEEYNTRLVKGGDEPIYLPANDEVPYNAIYFARGFYSSALHEIAHWLVAGKERRKLEDFGYWYEPDGRSEERQRDFEKVEVKPQALEWILATAAGFRYFASADNLNGNPGDTQPFKQAVYEQVKIYAEKGLPKRAETLRKALVAFYSTEDDINLAKFDVTCI
What is the function of this protein?
Is involved in the final hydroxylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Acts after beta-lysylation of 'Lys-34' by EpmA and EpmB.  EpmC adds an oxygen atom to the C5 position of 'Lys-34' and does not modify the added beta-lysine (By similarity).
What are the official names of this protein?
Elongation factor P hydroxylase, EF-P hydroxylase, EF-P post-translational modification enzyme C.
What is the protein family that this protein belongs to?
Belongs to the EpmC family.