PharMolix/UniProtQA huggingface dataset:
Protein: TRHO_METFK
Sequence: MPQIVVAALYKFVSLPDYQELQPGLLALCNAQGIKGTLLLAEEGINGTVAGSRAAIDALLTYLRQDSRMVDIDHKESFADEMPFYRMKVRLKKEIVTLGVPGISPNKKVGTYVKPEDWNTLISDPDVVVIDTRNNYEYEIGTFKGAIDPATTTFRQFPEFVRKNLDPAKNKKVAMFCTGGIRCEKASSYMLEQGFKEVYHLQGGILKYLETIPEEESLWEGECFVFDQRVAVKHGLQVGDYDQCFACRHPISAADMASSKYVKGISCPRCYDRMSAEKRARIAERQRQIEIARQRGEEHIGDNARQYSLIHKLSKTKKILPKT
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: XYLA_ENTFA
Sequence: MVYFPKIEKIKYEGTNTKNMYAFRHYNSEEIIMGKTMKEHLRFAVAYWHTMTQDGSDPFGKAVNKRSWLGESPMETAKKRVIAFFEILEKLDVEYFCFHDIDIAPEGNSLKEFFSNIDEITDLIKEKMDETGIKLLWNTANMFSNPRYVNGAASTNNANVYAIAAAQVKKGLDVSKKLGGENYVFWGGREGYETLLNTDMKFEQDNIARLFKMAIFYGEKIGHKPQFLIEPKPKEPSKHQYDFDAATTMAFILKYGLEKDFKLNLEANHATLAGHTFEHELNVARNYGALGSIDANQGDVLLGWDTDEFPTNVYDVTLAMYEILENGGIEPGGINFDSKVRRSSFEMEDLLLAHIAGMDTFARGLKSAMKLKEDRFFEDLKEQRYSSFKKGIGAKIISGKENLESLTNYALKNDEPIIESSHIEYVKNILNDYLY
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_BORPD
Sequence: MAKVQGKGAAEKENDDGLREKMIAVNRVSKVVKGGRTMSFAALTVVGDGDGRIGMGKGKAREVPVSVQKAMEQARRGMFKVALKNGTLHHTVVGKHGASTVLISPAAEGTGVIAGGPMRAIFEVMGVRNVVAKSLGSSNPYNMVRATLNGLRASLTPSEVAAKRGKTVEEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ATPE_ANAD2
Sequence: MALTLDIVTPEKRVLSVQVDEVRAPGVQGGFGVRLNHEPFMTALEPGRLTYVEGGREHHYAVGGGFLQVADNRVIVLADTAEAAGEIDVDRARKAFEDAQNRLLQLTEQDESHSAESARVRRAAARLTVAGR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MAC1_USTMA
Sequence: MINNALRTLISSATEQSLDDVLEHEFRTAVQLQQMDQFEWHQVEADLWKRTCLGHEASASFNQNIAHGHTELSLMTSWRVHQPSSSRITGSELELDQLVARVRQAWIQARYLRPEVGVELDTHTDPTVAQTMCYRLLRDEESIQEWLDETFVVKRLGDPGVATPAELCAYTYNRPLATKGKKSMLYLILPRLDDEQRTAYTIWNVSHAVTDGGSLAEVFNTLFQCVIDATPSEPYDSIYTPSAFELNVLPRMPRSVVMAYRQQYQPKPEEIAKAHKVAEVNMRMITEKMGESLALMPSTSWPERKHETVCLCRELEANEVRELLKFAKQVHSGITYLASAATILSAAETFPERKASSKGALVGMVRNARRWISATPLDASLGASTPLGSDAVFLWVPIDTHKTLEPSFSRMQELVTTARHIRHELDKHLTTPHCISSYPYVAESSIQGLNQQWSQIKAVQSPSSSSSQKEIAGIIGAQAPGFSSVGMMRIRPRFEPVSANARASGLWLERTDFTHTGRQINASPWISMFNVDGRIKLQLGFDTKFHEVEKMNQWLDRTVVWMRICAAAAATTSTSVSSTSVDATAPVFARL
What is the function of this protein?
Acyl-CoA-dependent acyltransferase; part of the gene cluster that mediates the biosynthesis of mannosylerythritol lipids (MELs), surface-active substances that enhance the availability of water-insoluble substrates (PubMed:15932999, PubMed:16885300).  Mannosylerythritol lipid production is responsible for hemolytic activity of Ustilago maydis (PubMed:15932999).  Depending on the number of acetyl groups, mannosylerythritol lipids can be differentiated into MEL A (fully acetylated), MEL B and MEL C (monoacetylated at R-6 and R-4, respectively), and the fully deacetylated MEL D (PubMed:31103599).  The first step in the pathway is the generation of mannosylerythritol by the glycosyltransferase EMT1 which catalyzes the transfer of GDP-mannose to the C-4 atom of meso-erythritol (PubMed:15932999).  This reaction has to be stereospecific, since only mannosyl-D-erythritol is generated (PubMed:15932999).  The produced disaccharide is subsequently acylated with fatty acids of various lengths derived from the peroxisomal beta-oxidation by the peroxisomal acyltransferases MAC1 and MAC2 at positions C-2 and C-3, repectively (PubMed:16885300, PubMed:24835306, PubMed:31103599).  The existence of MEL derivatives which carry an acetyl group at C-2 implies that at least MAC1 also accepts acetyl-CoA as a donor (PubMed:15932999).  The final step of MEL biosynthesis is the acetylation of the fully acylated mannosylerythritol lipids catalyzed by the acetyl-CoA-dependent acetyltransferase MAT1 (PubMed:16885300).  MAT1 displays a relaxed regioselectivity and is able to transfer acetylgroups to both positions C-4 and C-6 of the mannosyl moiety (PubMed:15932999).
What are the official names of this protein?
Acyl-CoA-dependent acyltransferase MAC1, Mannosylerythritol lipids (MELs) biosynthesis cluster protein MAC1.
What is the protein family that this protein belongs to?
Belongs to the trichothecene O-acetyltransferase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: LPXD_CELJU
Sequence: MKRSYSLAELARYLDAELKGDPDYEIRALATLQSASAHQLGFIANPVYQKYLATTQAGALLLRPDFSEYYSGHQLLVANPYQAYAHVSALFDPSVEFSPGIHPTAVIGDGCHLGHGVSIAAHVVLGANVSLGDGAALGPGTVIGDDCHIGARTRLAANVTLYQGVSLGDDCILHAGCVLGADGFGFAPSAGGWIKIHQLGSVVVGNRVEIGASTCIDRGALDDTRIEDGVIIDNLVQIAHNVRIGKNTAIAGHTAIAGSTQIGANCTIAGAVGIVGHLHITDGVHITAMTLVTHSIDKPGSYSSGTPMSQTREWRKNAARFRQLDGLANRLIKIERDQSAE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: ARFA_MYCBO
Sequence: MASKAGLGQTPATTDARRTQKFYRGSPGRPWLIGAVVIPLLIAAIGYGAFERPQSVTGPTGVLPTLTPTSTRGASALSLSLLSISRSGNTVTLIGDFPDEAAKAALMTALNGLLAPGVNVIDQIHVDPVVRSLDFSSAEPVFTASVPIPDFGLKVERDTVTLTGTAPSSEHKDAVKRAATSTWPDMKIVNNIEVTGQAPPGPPASGPCADLQSAINAVTGGPIAFGNDGASLIPADYEILNRVADKLKACPDARVTINGYTDNTGSEGINIPLSAQRAKIVADYLVARGVAGDHIATVGLGSVNPIASNATPEGRAKNRRVEIVVN
What is the function of this protein?
May play a role in ammonia secretion that neutralizes the medium at pH 5. 5, although it does not play a direct role in ammonia transport.  Binds peptidoglycan.  Expression depends on arfB and arfC (By similarity).
What are the official names of this protein?
Peptidoglycan-binding protein ArfA, Outer membrane protein ArfA.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. ArfA family.
What are the subcellular locations of this protein?
Cell outer membrane. Note=Does not have a cleavable signal sequence.
Protein: YHBP_ECODH
Sequence: METLIAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFYILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYNRRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRDSGTEQA
What are the official names of this protein?
UPF0306 protein YhbP.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: TLCA_RICCN
Sequence: MNNPKNDNYLSELSKVIWPIERYENKKFLPMAFMMFCILLNYSTLRSIKDGFVVTDIGAEAISFLKTYIVLPSAVIAMVIYVKLCDILKQENVFYVITSFFLGYFALFAFVLYPYPDLVHPDPETIESWSVAYPNVKWFIRIVGKWSFASFYTMAELWGTMMLSLLFWQFANQITKTDEAKRFYSMFGLLANLALPVTSVIIGYCLHEKTQIVAEHLKFVPLFVIMITSSFLVILTYRWMNKNVLTDPRLYDPALVKEKKAKAKMSLIDSFKMIFTSKYVGYIALLLIAYGVSVNLVEGVWKSKVKELYPTKEAYTIYMGKFQFYQGWVAIAFMLIGSNILRKVSWLTAAMITPLMMLITGAAFFAFIFFDSVIAMHLTGILASGPLALAVMIGMIQNVLSKGVKYSLFDATKNMAYIPLDKDLRVKGQAAVEVIGGRFGKSGGAIIQSTFFILFPAFGFVEATPYFASIFFVIVILWIYAVKGLNKEYKVLVNKTEK
What is the function of this protein?
Provides the rickettsial cell with host ATP in exchange for rickettsial ADP.  This is an obligate exchange system.  This energy acquiring activity is an important component of rickettsial parasitism (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein 1, ADP/ATP translocase 1.
What is the protein family that this protein belongs to?
Belongs to the ADP/ATP translocase tlc family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HUTU_ALISL
Sequence: MTHTSSSNPRLDESRTIIAPTGTALTAKSWLTEAPLRMLMNNLHPDVAEHPHALVVYGGIGRAARNWQCYDKIVEVLTRLEDDETLLVQSGKPVGVFKTHTNAPRVLIANSNIVPHWANWEHFNELDKQGLMMYGQMTAGSWIYIGSQGIVQGTYETFVAMARQHFDGKAAGRWVLTGGLGGMGGAQPLAATMAGFSMLAVECDESRIDYRLRTGYVDRKATTLDEALAIIEESKQSGTPVSVGLLGNAADVYADIVQRGIVPDITTDQTSAHDPLNGYLPQGWSMEQAAEMRLKDEPAVVIAAKKSMAIQVQAMLDLQKSGSATVDYGNNIRQMALEEGVANAFDFPGFVPAYIRPLFCEGIGPFRWAALSGDPEDIYKTDQKVKELIPDNPHLHNWLDMARERIQFQGLPARICWVGLKDRARLGKAFNEMVKNGELKAPIVIGRDHLDSGSVASPNRETEGMMDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDDAAERVGRVLHNDPATGVMRHADAGYDIAINCAKEQNLDLPMLSEPK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR3_ARAHI
Sequence: MGQKINPLGFRLGTTQSHHSVWFAQPKKYSEGLEEDKKIRDCIKNYVQKNIRISSGMEGIARIEIQKRIDLIQIIIYMGFPKLLIEDKPRRVEELQMNVQKELNCVNRKLNIAITRISNPYGQPNILAEFIAGQLKNRVSFRKAMKKAIELTEQANTKGIQVQIAGRIDGKEIARVEWIREGRVPLQTIDAKIDYCSYTVRTIYGVLGIKIWIFVDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYP_YERPN
Sequence: MRTSQYLLSTQKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRGEINSYKQLPLNFFQIQTKFRDEVRPRFGVMRAREFLMKDAYSFHTTQESLQETYDAMYTAYSKIFSRMDLNFRAVLADTGSIGGSASHEFQVLAESGEDDIVFSTGSDYAANIEFAEALAPTEPRAPATEELRIVDTPNAKTIAELVEQFKLPIEKTVKTLLVHAHEESGHKLVALLVRGDHDLNEIKAEKLPQVAKPLTFASEEEIRAAIGAGPGSLGPVNLSLPVIADHSVAVMSDFGAGANIDGKHYFGINWERDLALPLVADLRNVVEGDISPDGKGTLQIKRGIEVGHIFQLGTKYSEVMKATVQGEDGRNQVMTMGCYGIGVSRVVAAAIEQNHDDRGIIWPDAIAPFQVAILPMNMHKSFRVKELAEELYTTLRSHGIDVILDDRKERPGVMFADMELIGVPHNIVIGDRNLDSEEVEYKNRRVGEKQMIKTSEIVEFLLSQIKR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_PROM4
Sequence: MPKLKTRKAAAKRFKVTGTGKFMRRRAFRNHLLDHKSTKLKRHLATKAVVDERDADNVSLMLPYS
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PP2A3_PARTE
Sequence: MASLNKLSSNDIGNIDRQIAKLKQGQILTESEIKSLCIKAKEILSDEPNIIQVRAPLTICGDIHGQFHDLIELFQIGGNLPDTNYLFLGDYVDRGSQSVETFSLMLSLKVRYKDRIVLLRGNHENREINKVYGFYDECFRKYGNEIVWKQFTEVFGYLPLSAIVEQQIFCAHGGLSPAMESVDQIKQLNRVQDIPHEGLMCDLLWSDPEETKNGWGISPRGAGWTWGCDITEKFLHSNKLKQIARAHQLVMEGIQKVHNQKTITIFSAPNYCYRCGNQACIVEVDEQLRMNQTQFEPAPRENEPHTTRRVPDYFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP2A catalytic subunit 3, PPN 3.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
Protein: RL1D1_MOUSE
Sequence: MKGSASESPSASVAEATTTDVQVTPTALLQLDREQIRKAVEVISNRSKSKKNNNELLLSGSENLFLMVILWKIPEKELRVKVPLPHSILSESSDVCLFTKDEFDSPEQTEGFYKKLLKKHGVNTISQIIPFKTLKTEYKAYEAKLRLLGSFEVFITDARIRRHLPSHIGRHFYQRKKVPVSVNLLAKNLSKEINRCITGTVLNISKRGSCSTIRIGHTGMETEHIVDNILAVSEMLSEKLPEKWQSVKLLFLKTEKSVSLPIFSSFVTSQDENAVSLRSLRKQELKKRKRENAKLKKESKMLRKKSKKATSLLTQSGLASSAPAKSPGAQKKKTNKAHKKQKVTEECEEAIPQLVPIGETPDKENVKMQENITGKTPKSKSDPSTPKGKKRKALLATETPEASAPGTSGKKQKKDVQEFRKPEASSFSTPRKSGKKASNTPRDKKTKAAHSN
What is the function of this protein?
Regulates cellular senescence through inhibition of PTEN translation.  Acts as a pro-apoptotic regulator in response to DNA damage.
What are the official names of this protein?
Ribosomal L1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family. Highly divergent.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GLO2_PSEFS
Sequence: MIQISALPAFTDNYIWLLQDPHTQRCAVVDPGDAAPVLDWLEQNPGWALSDILVTHHHHDHVGGVEQLKGATNAKVYGPANEKIPARDVALNDNDRITVLGWDFDIYTVPGHTLGHITFYHSGVLLCGDTLFAAGCGRLFEGTPEQMYTSLERLAALPADTRVYCTHEYTQSNLKFAQAVEPDNADIAERVESVRQLRARGEITLPSNLALERLTNPFLRTSETSVKQKADERNGRDNRSGAEVFASLRAWKDKF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: T4S1_PONAB
Sequence: MCYGKCARCIGHSLVGLALLCIAANILLYFPNGETRYASENHLSRFVWFFSGIVGGGLLMLLPAFVLIGLEQDDCCGCCGHENCGKRCAMLSSVLAALIGIAGSGYCVIVAALGLAEGPLCLDSLGQWNYTFASTEGQYLLDTSTWSQCTEPKHIVEWNVSLFSILLALGGIEFILCLIQVINGVLGGICGFCCSRQQQYDC
What are the official names of this protein?
Transmembrane 4 L6 family member 1.
What is the protein family that this protein belongs to?
Belongs to the L6 tetraspanin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Colocalizes with SDCBP2 in the apical region of the cell.
Protein: RR2_ANGEV
Sequence: MQQKNWNINLEEMMEAGIHFGHRTQKWNPKMSPYIFTERKGVHILNLTQTARFLSEACDLVFHAANEGKQFLIVGTKYQVSDLIASAAIKARCHYVNQKWLGGMLTNWSTMETRLQRFQDLENKANTGGFNRLPKREAAILKRQLSQLQKYLGGIKYMIDPPDIVIIADQHKESTAIKECINLGIPTICVVDTDCDPDLTDIPIPANDDARSSIRWILNKLTFAIHEGQSNYMLSKDS
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y438_BACHK
Sequence: MGFPKEGEKVQIHSYKHNGSIHRMWEETTILKGTQSLVIGANDRTVVTESDGRTWITREPAICYFHANYWFNVIGMLREEGVYYYCNLSSPFAYDSEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHSQIMQYPPVIDTILKRNVAQLTQWIHQRKGPFAPDFVDMWYERYLMYRN
What are the official names of this protein?
UPF0374 protein BT9727_0438.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: IGS10_MOUSE
Sequence: MQKRGREVSCLLISLTAICLVVTPGSRVCPRRCACYVPTEVHCTFRYLTSIPDGIPANVERVNLGYNSLTRLTENDFSGLSRLELLMLHSNGIHRVSDKTFSGLQSLQVLKMSYNKVQIIEKDTLYGLRSLTRLHLDHNNIEFINPEAFYGLTLLRLVHLEGNRLTKLHPDTFVSLSYLQIFKTSFIKYLYLSDNFLTSLPKEMVSSMPNLESLYLHGNPWTCDCHLKWLSEWMQGNPDIIKCKKERIPSSPQQCPLCMNPRISKGRSIAMVPSGSFLCTKPTIDPSLKSKSLGIQEDNGSASVSPQDFIEPFGSLSLNMTDLSGNKANVICSIQKPSRTLPIAFTEENDYIMLNMSFSTNLVCSVNYNHIQPVWQLLALYSDSPLILERKPQHTETPLLSPKYQQVALRPEDTFTNIEADFKADPFWFQQEKISLQLNRTATTLSTLQIQFSTDAQITLPKAEMRPVKRKWTMILMMNNTRLEHTVLVGGTIALDCPGKGDPSPHLEWVLADGSKVRAPYVSEDGRILIDKKGKLELQMADTFDAGLYHCISTNDADADILTYRITVVEPYVENKHENGALHTVIMGEILDLPCLSTGIPDASISWILPRNTVFSQSSRDMQILNNGTLRILQATPKDQGHYRCVAANPSGADFSSFQVSVQMKGQRTIEHDRDIDGSGLEEPKPSVLLKQPPSLKLPASSLTGTEAGKQVSGIHKKNKHRDLTHRRRGDSTLRRFREHRRQLPLSARRIDPQHWAALLEKAKKNSVLRKQENTTVKPTPLAIPLVELAGEEKDASGLTPPDEEFTVLKTKAFGVPERSPTADSRPVNHGFVTSSASGTEVSSTVNPQTLLPTHLPDFKLFNVVDSAAVSKSMNRPVTSKIEDTTHQNPIIIFPSVAEIQDSAQVGRTSSQSAHPATGGAMATYGYTTMLSSFTNKANTVLQSANPTESYGPQIPLTEVSRVSSNNSLAHTTKDPGFSKRPSDSHTTAPSLFQTPRNNSTGNVGRERTIWSRGRAISPYRTPVLRRHRHRIVRPALKGPANRNISQVSATEPPGMCRTCSSTERLTMATAALSVTGSSHTTLPKANNVGIISEESTTVVKKPSLLLKNKQDVDIETITTTINYFRSESTHMTPTEASMISAPTSISLGKTPIDTSGHLSMPRTIQAGTDLVVTPPLSSPLSQPSIPTKATSTKLSRRKIPWHPIFANNHNKEGMLKNLHQFGLQKNTATKPPEKAPLLPTDHGSSSPSTTLLASLTPAQSATMAATRRNGTEVQGARSLSAGKEQPFINSFLVLPSTTRKRSSTLSFLSVETPTVTTPPVIASAIISETQEVRSKKAKDQTKGSLKNRKGPTITPRQISGYSTYSVPTTTDTPLAFSHSPGKVTGRTVSTAAPHSAASLLGITELPQKCTHTSGNITASETTLLSKSQESTAMKRASATPPLLSSGAPRMPTPSPPPFTKVVVTDSEVPAVFKMMSNRMVTIYESSRHDIDLQQPSAEASPNPEILTGSTDFPLSSLLTSTPMPAPRVDKPQDSQWKPSPWPENKFQLRSYSETIEKGKRPEISLSPHLSFPEASTHALHWNAQRHAEKSVFDKKPAQNPTSKHLPYDSLPKTILKKPRIIGGKAASFTVPTNSDVLLPCEAVGDPKPTIHWTRVSSGREISRGIQKTRFHVLPNGTLSIQRVSIQDRGQYLCAASNPLGVDHLHVTLSVVSYPARILESHVKEITAHSGSTVKLKCRVEGMPRPTISWILANQTVVSETPEGSRKVWVTPDGTLIIHNLSLYDRGFYKCVANNPSGQDSLLVKIQVITAPPVIIEQKRQAIVGVLGESLKLPCTAKGTPQPSVHWVLYDGTELKPLQLTHSRFFLYPNGTLYIRNIVSSVRGTYECIATSSSGSERRVVILRVEEQETVPRIETASQKWTEVNLGEKLLLNCSATGDPKPTIIWKLPSKVVIDQWHRMGSRIHVYPNGSLVIGSVTEKDGGDYLCVARNKMGDDLVLMHVRLRLTPAKIEHKQHFKKQVLHGKDFQVDCKASGSPVPEVSWSLPDGTVVNNVAQADDSGYRTKRYTLFHNGTLYFNKVGMAEEGDYICSAQNTLGKDEMKVHLTVLTAIPRIRQNYRSNVRIKAGDTAVLDCEVTGEPKPNVFWLLPSNNVISFSNDRFIFHANGTLSINKVKPLDSGKYVCVAQNPSGDDTKTYKLDIVSRPPLINGLYANKTVIKATAIQHSKKHLDCRADGVPPPQITWIMPDNIFLTAPYYGGRITVHQNGTLEIRNIRLSDSADFTCVVRSEGGESVLVVQLKVLEMLRRPTFRNPFNEKVVAQVGKPVAMNCSVDGNPTPEIIWILPDGTQFANGPQNSPYLMASNGSLIVYKATRNKSGKYRCTARNKVGYIEKLILLEIGQKPVILTYEPGMIKSAGGESLSLHCVSDGIPKPNVKWTTPGGLVIDRPQVGGKYILHENGTLVIKETTAHDRGNYICKAQNSVGQAVISVPVTIVAYPPRIINYLPRSMLRRTGEAMQLHCVALGVPKPQITWETPGYSLLSTATERRPHRSEMLPLQGTLVIQNLRASDSGVYKCRAQNVLGADYATTYIQVL
What is the function of this protein?
Involved in the control of early migration of neurons expressing gonadotropin-releasing hormone (GNRH neurons) (PubMed:27137492).  May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity).
What are the official names of this protein?
Immunoglobulin superfamily member 10, IgSF10.
What are the subcellular locations of this protein?
Secreted.
Protein: TUS_YERP3
Sequence: MNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKGTEHQPIEQITVNITEGEHAKKLGLQHFQRLFLHHQGQHVSSKAALRLPGVLCFSVTDKELIECQDIIKKTNQLKAELEHIITVESGLPSEQRFEFVHTHLHGLITLNTYRTITPLINPSSVRFGWANKHIIKNVTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTRLKIKRPVKVQPIARVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKHKYKPDAKPLRLLVPRLHLYVELEP
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_CORDI
Sequence: MSTNNTIKTPYEDLLRTILEQGSHKDDRTGTGTTSLFGQQMRFDLTEAFPLITTKKVYWKGVIGELLWFLQGSSNVRWLQKRNIHIWDEWASEEGELGPVYGVQWRSWPTPDGQHVDQIAQALDILKNNPDSRRNIVSAWNVADLNNMALPPCHLLFQLYVADGKLSCQLYQRSADMFLGVPFNIASYSALTHMLAQQAGLKVGEFIWTGGDCHIYDNHREQVLTQLSREPRPYPQLTLRKASSIFDYDFDDFTIEGYDPHPAIRGEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR1_STAAS
Sequence: MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVHLKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase 1.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PB2_I78A8
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPVTSTVHYPKVYKTYFDKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQNCKISPLMVAYMLERELVRKTRFLPVAGGTSSMYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIKVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAIVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDESTSGVESAVLRGFLILGKEDRRYGPALSINELSNLTKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: ORN_BURP6
Sequence: MTDISAVAGQPALVRNELNLVWLDMEMTGLDPDTDRIIEIAVVVTNSTLDIAVEGPVLAIHQSDETLAKMDDWNKNTHGRSGLIDRVRASSVTEADAAAQIAAFLAEHVPPGKSPMCGNSICQDRRFMARWMPELERFFHYRNLDVSTLKELCRRWQPAIYKGFQKRAMHTALADIHESIDELKYYRERFLIPAAPAGETA
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.