PharMolix/UniProtQA huggingface dataset:
Protein: YCF2_NASOF
Sequence: MKGHQFKSWIFELREIVREIKNSHYFLDSWTQFNSVGSFIHIFFHQERFRKLLDPRIFSILLLRNSQGSTSNRYFTIKGVVLFVVAALLYRINNRNLVESKNLYLKGLLPIPMNSIGPRNDTSEESFGSSNINRLIVSLLYLTKGKKISESCFRDPKESTWVLPITKKCIMPESNWSSRWWRNWIGKKRDFCCKISNETVAGIDISFKEKDIKYLEFLFVYYMDDPIRKGHDWELFNRLSPSKRRNIINLNSGQLFEILVKDWICYLMFAFREKIPLEVEGFFKQQGAGSTIQSNDIEHVSHLFSRNKWAISLQNCAQFHMWQFHQDLFVSWGKNPHESDFLRKISRENWIWLDNVWLVNKDRFFSKVRNVSSNIQYDSTRSSFVQVTDSSQLNGSSDQFIDPFDSISNEDSEYHYHTLINQREIQQLKERSILWDPSFIQTEGREIESDRFPKYLSGYSSMPRLFTEREKRMNNHLLPEESEEFLGNSTRAIRSFFSDRWSELHLGSNPTERSTRDQKLLKKEQDVSFVPSRRSENQEIVNIFKIITYLQNTVSIHPISSDLGCDMVPKDELDMDSSNKISFLNKNPFFDLFHLFHERKRGGYTLRHDFESEERFQEMADLFTLSITEPDLVYHKGFAFSIDSYGLDQRQFLKEGFNSRDESKKKSLLVLPPIFSEENESFYRRIRKNWVRISCGNYLEDPKRVVFASNNIMEAVNQYRLIRNLIQIQFQYSPYGYIRNVLNRFFLMKRPDRNFEYGIQRDLIGNDTLNHRTIMKDTINQHLSNLKKSQKKWFDPLIFLSRTERSINRDPNAYRYKWSNGSKNFQEHLEHFVSERKSRFQVVFDRLCINQYSIDWSEVIDKKDLSKSLRFFLSKLLRFFLSKLLLFLSKLLLFLSNSLPFFFVSFENIPIHRSEIHIYELKGPNDQLCNQLLESIGLQIVHLKKLKPFLLDDHNTSQKSKFLINGGTISPFLFNKIPKWMIDSFHTRKNRRKSFDNTDSYFSIVSHDQDNWLNPVKPFQRSSLISSFSKANRLRFLNNPHHFCFYCNKRFPFYVEKARLNNSDFTYGQFLTILFLHNKIFSSCGGKKKHAFLERDTISPSSIESQVSNIFISNDFPQSGDERYNLYKSFHFPIRSDPLVRRAIYSIAAISGTPLIEGQRVNFERTYCQTLSDMNLSDSEEKSLHQYLNFNSNMGLIHTPCSEKYLQRKKRSLCLKKCVDKGQMDRTFQRDSAFSTLSKLNLFQTYMPWFFTSTGYKYLNLIFLDTFSDLLRILSSSQKFVSIFHDIMHGLDISWRILQKKLCLPQRNLISEISSKSLHNILLSEEMIHRNNESSLISTHLRSPNVREVLYSILFLLLVAGYIVRTHLLFVSRAYSELQTEFEKIKSLMIPSYMIELRKLLDRYPTSELNSFWLKNLFLVSLEQLGDCLEEIRGSGGNILRGGDPAYGVKSIRSKKKDLKINFIDIISIIPNPINQITFSRNTRHLSHTSKEIYSVIRKRKNVSGDWIDDKIESWVANSDSIDDKEREFLVQFSTLRAEKRIDQILLSLTHSDHLSKNDSGYQMIEQPGTIYLRYLVDIHKKYLMNYEFNTSCLAERRIFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSPSRSILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFFIDDIDIDDSDDIDASNDIDRELDTELELLTMMNALTMDMMSEIDLFYITLQFELAKAMSPCIIWIPNIHDLDVNESNYLALGLLVNSLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFESITMGSSARDLVALTNEALSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLISNCPIDPISIYRKKKSCNEGDSYLYKWYFELRTSMKKFTILLYLLSCSAGSVAQDLWSLPGPDEKNRITSYGFIENDSDLVHGLLEVQGALVGSSRTEKDCSQFDNDRVTLLFRSEPRDPLYMMQDGSCSIVDQRFLYEKYESEFEEGEGEGVLDPQQIEEDLFNHIVWAPRIWRPRGFLFDCIERPNELGFPYLAGSFRGKRIIYDEKYELQENDSEFLQSGTMQYQRRDRSSKEQGFFRISQFIWDPADPLFFLFKDQPFVSVFSHREFFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKHFELLIQRQRWLRTNSSLSNGFFRSNTRSESYQYLSNLFLSNGTLLDRMTKTLLKKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: NORM_VIBPA
Sequence: MHRYKEEASSLIKLATPVLIASVAQTGMGFVDTVMAGGVSATDMAAVSVASSIWLPSILFGIGLLMALVPVVAQLNGSARREKIPFEIQQGVVLALLISIPIIGVLLQTQFILQLMDVEAVMAGKTVGYIHAVIFAVPAFLLFQTLRSFTDGMSLTKPAMVIGFIGLLLNIPLNWIFVYGKFGAPELGGVGCGVATTIVYWVMFALLLAYVMTSSRLKSINVFGEYHKPQWKAQVRLFKLGFPVAAALFFEVTLFAVVALLVSPLGPIIVAAHQVAINFSSLVFMLPMSVGAAVSIRVGHRLGEENVDGARVASRVGIMVGLALATITAIITVLSRELIAELYTNNPEVISLAMQLLLFAAVYQCTDAVQVIAAGALRGYKDMRAIFNRTFIAYWILGLPTGYILGRTDWIVEPMGAQGFWLGFIIGLTAAALMLGVRLRWMHRQEPDVQLNFSLQ
What is the function of this protein?
Multidrug efflux pump that functions as a Na(+)/drug antiporter.  Confers resistance to several drugs, such as norfloxacin, ciprofloxacin, ethidium, kanamycin and streptomycin.
What are the official names of this protein?
Multidrug resistance protein NorM, Multidrug-efflux transporter, Na(+)/drug antiporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 4HYPE_PSEF5
Sequence: MKKITVIDSHTGGEPTRLVIDGFPDLGRGSMAERLQILEREHDQWRRACVLEPRGSDVLVGALLCQPQAGDACAGVIFFNNSGYLGMCGHGTIGLVRSLYHLGRIDQGVHRIETPVGTVEATLHEDLSVSVRNVPAYRYRTQVMLQLPGHGKVHGDIAWGGNWFFLISDHGQRIALDNVEALTHYTRDVRQALEAAGITGAEGGVIDHIELFADDPQADSRNFVLCPGKAYDRSPCGTGTSAKLACLAADGKLAPGQAWRQASVIGSQFSAHYEKVGEQLIPILRGSAHISAEATLLLDDSDPFVWGIGS
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate.  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase, 4Hyp 2-epimerase, 4HypE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: RS15_SALHS
Sequence: MSLSTEATAKIVSEFGRDANDTGSTDVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HYPA_METAR
Sequence: MHELSIATDLINTALETAKQNNAREVISITVEIGELALINPEQLQFMYQVLTEENLLKGSELIIINVPAVAECQCGYKGPVPDKTTCACPNCGLTMRAVEGRDICLKTMEIEV
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: FMRFA_AGRIP
Sequence: MSCSRTVALLAALWLVVGATSSPVRRSPDLEARRRSAIDRSMIRFGRSYPPEPSAADIREAFERPTRRGNSFLRFGRSQPLTLSTDDLVSLLRAYEEDYDTPMTKKSASFVRFGRDPNFIRLGRSADDDKSAFEQNSELVVSGYPQRKSRARDHFIRLGRDSEEVNENEFEETEESRRKRSADSCHDCQS
What is the function of this protein?
In insects, FMRFamide and related peptides have modulatory actions at skeletal neuromuscular junctions, and peptides that are immunologically related to FMRFamide are released into the circulation from neurohemal organs.
What are the official names of this protein?
FMRFamide-related peptides.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3G_ASPOR
Sequence: MSKLANRADWADDEEFDDPSALPAQQVTTNKDGTKTVVSYRFNDEGKKVKVTRRIKTTVVREHVNPQVAERRSWAKFGLEKGHAPGPSFDTTSVGENIAFRPSINWKAQAAEAEKNGGEKGSMKDQLKDKKVKCRICSGEHFTARCPFKDTMAPVDEPTAGGAGEDDEAAAGAVGTGSGSYVPPHLRKGAAGGGERMGGKFEKDDLATLRVTNVSELAEEGELRDLFERFGRVTRVFLARDRETQRAKGFAFISFADRSDAARACEKMDGFGYRHLILRVEFAKRTT
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit homolog, eIF3 p33 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_BACAC
Sequence: MTGQLVQYGRHRQRRSYARISEVLELPNLIEIQTSSYQWFLDEGLREMFQDISPIEDFTGNLSLEFIDYSLGEPKYSVDECKERDVTYAAPLRVKVRLINKETGEVKEQDVFMGDFPLMTETGTFVINGAERVIVSQLVRSPSVYYSGKVDKNGKRGFTATVIPNRGAWLEYETDAKDVVYVRIDRTRKLPVTVLLRALGFGSDQEITELLGDNEYLSNTLEKDNTDSTEKALLEIYERLRPGEPPTVENAKSLLVSRFFDPKRYDLANVGRYKINKKLHIKNRLFNQRLAETLVDPETGEILAAEGTILDRRTLDRILPYLEKNIGFKTAKPMGGVVEGDVELQSIKIYAPESEGERVINVIGNANITRDVKHITPGDILASISYFFNLLYKVGDTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTNAITPQALINIRPVIAAIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSFAKVNEFGFIETPYRRVDPETGLVTGHVDYLTADEEDNYVVAQANMKLSEEGEFLDEDIVARFRGENIVTNKERIDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNPESPIVGTGMEYVSAKDSGAAVICKHPGIVERVEAREVWVRRYVEVDGQTVKGDLDRYKMQKFIRSNQGTCYNQRPIVSVGNEVVKGEILADGPSMELGELALGRNVLVGFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVGEDALRNLDERGIIRVGAEVKDGDLLVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGGGGIILDVKVFNREDGDELPPGVNQLVRAYIVQKRKISEGDKMAGRHGNKGVISRILPEEDMPYLPDGTPIDIMLNPLGVPSRMNIGQVLELHLGMAARYLGIHIATPVFDGAREEDVWGTIEEAGMANDAKTILYDGRTGEPFDNRVSVGVMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVIGRVKTYEAIVKGENVPEPGVPESFKVLIKELQSLGMDVKMMSSDDTEIEMRDTEDDDDHQSADKLNVEVETTKE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DEVS_MYCTU
Sequence: MTTGGLVDENDGAAMRPLRHTLSQLRLHELLVEVQDRVEQIVEGRDRLDGLVEAMLVVTAGLDLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIGHLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRVRDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANARLYQQAKARQSWIEATRDIATELLSGTEPATVFRLVAAEALKLTAADAALVAVPVDEDMPAADVGELLVIETVGSAVASIVGRTIPVAGAVLREVFVNGIPRRVDRVDLEGLDELADAGPALLLPLRARGTVAGVVVVLSQGGPGAFTDEQLEMMAAFADQAALAWQLATSQRRMRELDVLTDRDRIARDLHDHVIQRLFAIGLALQGAVPHERNPEVQQRLSDVVDDLQDVIQEIRTTIYDLHGASQGITRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAVVREAVSNAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQAGGEFTLASVPGASGTVLRWSAPLSQ
What is the function of this protein?
Member of the two-component regulatory system DevR/DevS (DosR/DosS) involved in onset of the dormancy response (PubMed:12953092).  Regulates an approximately 48-member regulon (PubMed:12953092, PubMed:11416222, PubMed:15033981, PubMed:18400743).  Required for full induction of the DevR (DosR) regulon; acts later than DosT to positively regulate expression of the DevR regulon during adaptation to anaerobiosis (PubMed:19487478).  Characterized as an oxygen sensor; O(2) acts as a switch, with O(2)-bound Fe(2+) protein inactive in autophosphorylation (PubMed:17371046, PubMed:17600145, PubMed:18975917, PubMed:19463006, PubMed:28977726).  Has also been suggested to act as a redox sensor, or perhaps as a dual oxygen/redox sensor (PubMed:17609369).  Autophosphorylates under anaerobic but not aerobic conditions, binding of NO or CO does not dramatically change the level of autophosphorylation of Fe(2+) protein, binding of O(2) inactivates kinase activity (PubMed:17600145, PubMed:18975917, PubMed:27235395).  Binds O(2), NO, CO (PubMed:17371046, PubMed:17609369, PubMed:17600145, PubMed:18975917, PubMed:27235395).  It is probably reduced by flavin nucleotides such as FMN and FAD (PubMed:19276084).  May be the primary sensor for CO (PubMed:18400743).  Donates a phosphate group to transcriptional regulator DevR (DosR) (PubMed:15033981, PubMed:15073296, PubMed:28977726).
What are the official names of this protein?
Oxygen sensor histidine kinase response regulator DevS/DosS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_SYNS3
Sequence: MESFAYILILGLAIATLFFAIAFRDPPKIGK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RIMM_BORAP
Sequence: MFIKGVILSSYGVNGYARIKSISNNFCDFINLKNNKVLLKKSNGFAIEVKVIDVNIKSNSLFLKFEGIDAPESVKPLIGFELWVDDSLASSLKEGEYYLGKLIGYTIVNDNRKLGEVVAFFEYLNNVFLEVKVGIKFFFIPFLSIYIGNIDAREKTIELKVLDLLR
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SHEHH
Sequence: MYNESPIIRRKSSRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVAQIKALEKVGADIVRVSVPTMDAAEAFKFIKQQTNIPLIADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVECARDKNIPIRIGVNGGSLEKDLMDKYKEPTPEALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVESYRLLAKQIIQPLHLGITEAGGARAGSVKSAVGLGMLLADGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNELEQRLEDIVTPMDVSIIGCVVNGPGEALVSDIGLTGGNRMSGYYDDGVRQKERFDNNNIVDSLEAKIRAKAAIVASRIPAQDLNK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RL36_CLOBH
Sequence: MKVRPSVKPICEKCKVIRRKGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: KBP_MOUSE
Sequence: MANAPGPEIREKFQAALALSRVELHKNPEKEPYKSKYGARALLEEVRALLGPAPEDEDEPAADDGPGDQALGAGEPREAEGPGAQRALRLAVVEFHLGVNHIDTEELSAGEEHLVRCLSLLRPYRLSLGCVSLYIQAQNNLGILWSEREEIETARTYLESSEALYSQYMKEIGSPPLDPTEHFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKIPATEDTPEVEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKRAVQFGTGELCDAISAVEEKVRYLRPLDFEEARELFLLGQHYVCEAKEFFQIDGYVTDHIEVVQDHSALFKVLSFFEADMERRCKMHKRRIAMLEPLTVDLNPQYYLLVSRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINSLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCETHPEAAQEIEVELELSKEMVSLLPTKMERFRAKMALT
What is the function of this protein?
Required for neuronal development and differentiation.  Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.
What are the official names of this protein?
KIF-binding protein, KIF1-binding protein.
What is the protein family that this protein belongs to?
Belongs to the KIF-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PLD3A_HUMAN
Sequence: MKIWSSEHVFGHPWDTVIQAAMRKYPNPMNPSVLGVDVLQRRVDGRGRLHSLRLLSTEWGLPSLVRAILGTSRTLTYIREHSVVDPVEKKMELCSTNITLTNLVSVNERLVYTPHPENPEMTVLTQEAIITVKGISLGSYLESLMANTISSNAKKGWAAIEWIIEHSESAVS
What is the function of this protein?
In vitro, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space.  Phosphatidic acid import is required for cardiolipin (CL) synthesis in the mitochondrial inner membrane.
What are the official names of this protein?
PRELI domain containing protein 3A, Protein slowmo homolog 1.
What is the protein family that this protein belongs to?
Belongs to the slowmo family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PB2_I47A0
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADRRITEMIPERNEQGQTLWSKMNDAGSDRVMVSPLAVTWWNRNGPMTSTVHYPKIYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVNICKAAMGLRISSSFSFAGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKTTRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMIGILPDMTPSTEMSMRGVRVSKMGVDEYSSAERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKIEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTVLGKDAGTLTEDPDEGTAGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: MATK_CYNHA
Sequence: MEEFQGYLEFDGARQHNFLYPFFFRESIYVLAYDHGLNRLNRNRSIFLENAGYDTKYSSLIVKRLIFRIYEQNHLIISTNDFSQNPFFGHTNHFYYQTISALFAVIVEIPFSLRLVSSFGGKQLAKSYNLQSIHSIFPFLEDKLSHLNYVLDVLIPYPIHLEILVQTLRYRVKDASSLHLLRFCLYEYWNWKNFYTQKKSILNTKFFLFLYNCHVCEYESIFFFLRKRSSHLRSTSSGVLFERIFFYRKIEHLLKVFVNNFQDILGLFKDPFIHYVRYHGKCILAAKDTPLLMNKWKYYFVNLWQWHFSVWFQWQKVHINKLSKDNLDFLGYLSSLRLNPLVVRSQMLENSFLIDNVRKEFDTKIPICSIIGSFAKEKFCNVLGYPISKSTWMDSSDSDILDRFVRICRNLSHYHSGSSKKKNLYRIKYILRLSCVKTLARKHKSTVRAFLKRLGSVLLEEFLTGEEQVLSLIFSRGYSPSQRFYRVRIWYLDIIYLNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GRPE_DICDI
Sequence: MNSLIRRGLVSIRTSTVIKPSSFGLMRNNRFYSTENNQEAAKPEETENKPAPGSLEETIEKLKEELEETKKQLLYTAADRENVRRFAKEDNEKAKKFGIQSFTKELLEVVDQLEMATNLFPKEKLDENKELKDLHEGVKMTEQLFLKIMGNQGLQRFNPIGEKFDFNNHHAIFELNDPTKENNTVGHVVKQGYKLHDRLVRPAMVGVNKIKPQ
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity).
What are the official names of this protein?
GrpE protein homolog, mitochondrial, dRoe1.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MRAY_CLOAB
Sequence: MGVIIYSVLISFLFSILQGPLFIPILHKLKFGQPIREDGPKNHMKKAGTPTMGGIIFITTAIIAMIIMRKNLNSNAVFAFVCFFSFAMIGLIDDSLKILHKKNEGLTSKQKFLLQIIVSAAISYYAYIRFGSDTFIPFLKITWTLPPIVYMAAVVFYFVAVTNAVNLTDGLDGLASSVTILVVTFFTVVSFSWHQYELSVFCGIIVGILLGFLKYNSYPAQIFMGDTGSIGLGGAVAAIALVLKLPLLVIIVGGIYVIEVLSDIIQVSYFKLTGKRVFKMAPIHHHFEKLGWHETKVVSVFSIVTVILCLIAFLSLI
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS13_RENSM
Sequence: MARLAGVDLPREKRLEVALTYIYGVGKTRAHKTLAETGISPDVRVKDLSDAELVQLRDYIEVNYKVEGDLRREVAADIRRKVEIGSYEGIRHRRGLPVRGQRTKTNARTRKGPKRTVAGKKKAGR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PCNP_RAT
Sequence: MGASCTATQSQFLLYTLTSSEETVGSVGDSCRGPEEEAEKPVKTKTVSSSNGGESSSRSAEKRSAEDEAADLPTKPTKMSKFGFAIGSQTARKASAISIRLGASKPKETVPTLAPKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQKLWERNIKSHLGNVHDQDN
What is the function of this protein?
May be involved in cell cycle regulation.
What are the official names of this protein?
PEST proteolytic signal-containing nuclear protein, PCNP, PEST-containing nuclear protein, Liver regeneration-related protein LRRG084.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOA_CHLT3
Sequence: MIQQMQMPEKLEVDEASYSNYYGKFIAQPLERGYGVTIGNAIRRVLLSSLPGTAITGIKIEGVLHEFSTIDGVKEDVPDIVLNLKQIRFRSISKRNAVVTLVLRGPKDFVAGDIVSPEGDFEVLNPEHHIATLNEDATLKIDVSVGRGRGYMPAEDNKPETMPIGYISVDSIFTPIRNVKYSVENTRVGQRTDYEKLSLEVETDGSIAPDEAVSMAGKIINDHVRLFSLFSPTQEEEVEEEVQQEDEEFENMRKLLMTRIEDLELSVRSHNCLRSAEIDTLGQLVSKREDELLGYKNFGKKSLAELKELLESKNLSFGMEVTKYRLNQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TMF1_MOUSE
Sequence: MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSAWAEAIPYGEPGISPPVSGGWDTSTWGLNSTSSEPQSPPTASQAITKPVRRTVVDESENFFSAFLSPSDAHTIQKSPVVSKPPSKSQRPEEEVKSSLQESSSPGQSRVSETAEVRDSVCVSGETSAVGTPSPVPEDKHEETAGEESEVKVPTVRLKASENVVNVNTTEDVSTTSTQSLTAETKDMALEPKEQKHEDRQSNTPSPPVSSFSSGTSTTSDIEVLDHESVISESSASSRQETSDAKSSLHLMQTSFQLLSASACPEYSRLDDFQKLNESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELPGKGYALVPIIVSPSTPKTKVVESTEENAEEEEGNETLVAPSEEAELEESGRSATPVNCDQPDILASPTAGSGGHSASGPATEQCEAVENQPKAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEALKEKDHKLFSVCSTPTMSRSSSISGVDAAGLQASFLSQDESHDHSFGPMSTSASGSNLYEAVRMGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQRLS
What is the function of this protein?
Potential coactivator of the androgen receptor.  May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER (By similarity).  Mediates STAT3 degradation.
What are the official names of this protein?
TATA element modulatory factor, TMF, Androgen receptor coactivator 160 kDa protein, Androgen receptor-associated protein of 160 kDa.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Golgi apparatus membrane. Note=Concentrated at the budding structures localized at the tips of cisternae.