PharMolix/UniProtQA huggingface dataset:
Protein: PEPE_ECODH
Sequence: MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQTWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGLLAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGEEAVPLEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTRO_NIACI
Sequence: MIALDTIQYYGQIPGVNHYNGKKEFMENAVKIAQLSDAYGIVGSLSFFNHSVLDPWAVSSVIMRHTERHVPLIALQPYMYPPYTAAKLIQSFTYLYDRRIDLNMITGAVTGELQQTGGYIDHSSRYKKLHEYVQVLRLLLESDSAVSFKGDYYELNNLEFKPLLPDKRLFPRIFMSGSSEEGLETGLKAADFVVTHPGPLEHFKRHFSEKVQGSAVQSAIRIEIIARESAEQAWKIAHARYPGNRQGKIQLRMKTNSESSWQRMLAELALASETYDEVFWMGGYMNGGIYSPVLVGDYEQVAAYLNEYYKLGVKAVLLGSMYSEEDFIHFSRVKEGISNPV
What is the function of this protein?
Monooxygenase component of a two-component system involved in the biosynthesis of the side chain of the aminoglycoside antibiotics in the biosynthetic pathway of butirosin.  Together with BtrV, mediates hydroxylation of gamma-L-Glu-GABA-S-BtrI.  Not able to hydroxylate free substrates, activation by the acyl-carrier protein is mandatory.  Octanoyl-S-[BtrI acyl-carrier protein] is also accepted as substrate.
What are the official names of this protein?
4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase BtrO, Butirosin biosynthesis protein O.
What is the protein family that this protein belongs to?
Belongs to the bacterial luciferase oxidoreductase family.
Protein: YGEY_ECOL6
Sequence: MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHRIKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDAHIDTVGIGNIKNWDFDPYEGMETDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYIIEQSGIRPEFVVSTEPTDCQVYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPILGELQELSQRLGYDEFLGKGTLTVSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGALDEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEEDHFTVKALVNAYEGLFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMYAAIPLSWLATE
What are the official names of this protein?
Uncharacterized protein YgeY.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: RS9_STRMU
Sequence: MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADLRLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLEVDPDFRDALKRAGLLTRDARMVERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: TP8L2_RHIFE
Sequence: MEPFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSAVLDELYRVSKEYTHSRPQAQRVIKDLIKVAVKVAVLHRSGCFGPSELALAARFRQKLQQGAMTALSFGEVDFTFEAAVLAGLLTECRDMLLELVEHHLTPKSHNRIRHVFDHFSDPGLLTALYGPDFTQHLGKICDGLRKMLDEGKL
What is the function of this protein?
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis.  Negative regulator of Toll-like receptor and T-cell receptor function.  Prevents hyperresponsiveness of the immune system and maintains immune homeostasis.  Inhibits JUN/AP1 and NF-kappa-B activation.  Promotes Fas-induced apoptosis (By similarity).
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8-like protein 2, TIPE2, TNF alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
Protein: GCSH_YERPA
Sequence: MSNVPTELKYALSHEWVRADGDGVYSVGITEHAQELLGDMVFVDLPEVGSDVSAGSDCAVAESVKAASDIYAPISGEIVAVNTELENSPELVNSAPYTDGWLFSIKAADESELDNLLDADAYLAAIEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: CCL2_MOUSE
Sequence: MQVPVMLLGLLFTVAGWSIHVLAQPDAVNAPLTCCYSFTSKMIPMSRLESYKRITSSRCPKEAVVFVTKLKREVCADPKKEWVQTYIKNLDRNQMRSEPTTLFKTASALRSSAPLNVKLTRKSEANASTTFSTTTSSTSVGVTSVTVN
What is the function of this protein?
Acts as a ligand for C-C chemokine receptor CCR2 (By similarity).  Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity).  Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity).  Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (PubMed:29993042).  Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (PubMed:29993042).
What are the official names of this protein?
C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Platelet-derived growth factor-inducible protein JE, Small-inducible cytokine A2.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PPS_METHJ
Sequence: MIPESHPRYKSLITREKLAQYTKTGIVSLEGLTAHGRGEAFDYLLGEETTESALRAEKIAAALLLSANHPVISVNGNTAALAAKEIAQLQLASKARVEVNLFHRTDERVQAISGLLKEHGITLVEGTVSRYIPLDHDRGLCHFDGMHSADVVLVPLEDGDRAQALIDLGKKVIAIDLNPLSRTSKVATVPVIDEVTRALANIARFCTELDQDEITGLTREIHGTGFIRDALEYIRERLLNVLD
What is the function of this protein?
Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
What are the official names of this protein?
4-phosphopantoate--beta-alanine ligase, Phosphopantothenate synthetase, PPS.
What is the protein family that this protein belongs to?
Belongs to the archaeal phosphopantothenate synthetase family.
Protein: SNP47_BOVIN
Sequence: MSGDTCVQTWPCSYYLELEKRWVPGRLSLTSLSLKFMTDKTRETLVSFPLSSIIEIKKEASHFIFSSITILERDHSKHWFSSLQPSRNAVFSVIEHFWRELLLSESGAAAEAASSSMTKGKELTCLMACTQKRLEDTARVLHHQGEQLDGISRGLDKMESDLDVADRLLTELESPSWWPFSSKLWKTPSETKPKWDASMADSKAFGKEGIVIQVPAVISQRTESHVKPGRLTVLVSGLEIYNSDSLLMHRFEREDVDDIKVHTPYEISICQRFIGKPDISYRLISAKMPEVIPILEVQFSKKIELLEVAMMLGSTRTSSLAEKGYSVWHAASGLMDQATHCEPSSGSQEGRPLQLQTSEPVISEEDTQELGQILRKLKGLALDTETELERQDEALDGITEAVDRATLTIDKHNRRMKKLT
What is the function of this protein?
May play a role in intracellular membrane fusion.
What are the official names of this protein?
Synaptosomal-associated protein 47, SNAP-47, Synaptosomal-associated 47 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the SVAP1 family.
What are the subcellular locations of this protein?
Endomembrane system. Cytoplasm, perinuclear region. Note=Appears to be exclusively membrane-bound.
Protein: RSBZ1_ORYSJ
Sequence: MEHVFAVDEIPDPLWAPPPPVQPAAAAGVDDVGAVSGGGLLERCPSGWNLERFLEELDGVPAPAASPDGAAIYPSPMPAAAAEAAARWSRGYGDREAVGVMPMPAAALPAAPASAAMDPVEYNAMLKRKLDEDLATVAMWRASGAIHSESPLGNKTSLSIVGSILSSQKCIEGNGILVQTKLSPGPNGGSGPYVNQNTDAHAKQATSGSSREPSPSEDDDMEGDAEAMGNMILDEEDKVKKRKESNRESARRSRSRKAARLKDLEEQVSLLRVENSSLLRRLADANQKYSAAAIDNRVLMADIEALRAKVRMAEESVKMVTGARQLHQAIPDMQSPLNVNSDASVPIQNNNPMNYFSNANNAGVNSFMHQVSPAFQIVDSVEKIDPTDPVQLQQQQMASLQHLQNRACGGGASSNEYTAWGSSLMDANELVNMELQ
What is the function of this protein?
Transcriptional activator that binds to the DNA specific sequence 5'-TGAGTCA-3' found in seed storage protein gene promoters.  Involved in the endosperm-specific regulation of storage protein genes (PubMed:15685292).  Can activate the expression of genes encoding for the seed storage proteins glutelin, prolamin, globulin and the allergen RAG1.  Functions synergistically with DOF3/RPBF to positively regulate quantitatively many seed storage protein genes (PubMed:16798940, PubMed:19473328).  Functions synergistically with DOF3/RPBF to positively regulate some metabolic enzymes, such as alanine aminotransferase and pyruvate phosphate dikinase, that are expressed in developing seeds (PubMed:16798940).  Functions synergistically with DOF3/RPBF to positively regulate genes that are key players in the development of aleurone layers (PubMed:19473328).  Functions synergistically with DOF3/RPBF to positively regulate the glutelin GLUD-1 gene in endosperm of developing seeds (PubMed:18980953).  Can activate the expression of the bifunctional lysine-degrading enzyme, lysine ketoglutarate reductase/saccharopine dehydrogenase (LKR/SDH), one of the key regulators determining free lysine content in plants (PubMed:21037241).  Functions as a key regulator of starch synthesis in seeds, by direct binding to the promoters of starch-synthesizing genes, such as AGPL3, WAXXY and SBE1 (PubMed:23846875).
What are the official names of this protein?
bZIP transcription factor RISBZ1, Rice seed bZIP1, bZIP transcription factor 58, OsbZIP58.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS15_PROMM
Sequence: MSLDTTEKQQLINANQTHGTDTGSVEVQVAMLSERITKLSSHLQENKHDFSSRQGLLKMIGRRKRLLSYVRGKSEQRYNGLITKLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MOBA_PSEAB
Sequence: MPDSALPPCSILLLAGGRGQRMGGRDKGLIEWQGLPLIAHLHRLVRPLTDDLIVSCNRNQERYAAYADRLVSDDSRDFPGPLAGIRAGLAVARHPWLLVLPCDAPRIDRALLETLLQAAGRTPARPWMLRCGGQWEPLFSLIPTHLAEEIEHAWRQGDRSPRHVLLPLGAEAIELAAGDPRLANLNTPELLANHRELK
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPT_ECOBW
Sequence: MKRISTTITTTITITTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: NANK_ECO27
Sequence: MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPQALRDALSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIAINDAQAAAWAEYQALDGDITDIVFITVSTGVGGGVVSGGKLRTGPGGLAGHIGHTLADPHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGANAKTIFTRAGQGDEQAQQLIHRSARTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPEAFHVDLLAAHYRHDAGLLGAALLAQGEKL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: GLN11_ARATH
Sequence: MSLVSDLINLNLSDSTDKIIAEYIWVGGSGMDMRSKARTLPGPVTDPSQLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGNNILVMCDAYTPAGEPIPTNKRHAAAKVFSNPDVAAEVPWYGIEQEYTLLQKDVKWPVGWPIGGYPGPQGPYYCGIGADKSFGRDVVDSHYKACLYAGINISGINGEVMPGQWEFQVGPAVGISAADEIWVARYILERITEIAGVVVSFDPKPIPGDWNGAGAHCNYSTKSMREEGGYEIIKKAIDKLGLRHKEHIAAYGEGNERRLTGHHETADINTFLWGVANRGASIRVGRDTEKEGKGYFEDRRPASNMDPYIVTSMIAETTILWNP
What is the function of this protein?
High-affinity glutamine synthetase which catalyzes the synthesis of glutamine from ammonium and glutamate (PubMed:14757761).  May contribute to the homeostatic control of glutamine synthesis in roots.
What are the official names of this protein?
Glutamine synthetase cytosolic isozyme 1-1, Glutamate--ammonia ligase GLN1;1, GLN1;1.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
Protein: YRAQ_ECOLI
Sequence: MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWEPYYGKAFTAAETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLRTLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPVLNPATLVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFSRWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVVAMAVAGCLFVIPTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAVSGVIVGGLALLF
What are the official names of this protein?
UPF0718 protein YraQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0718 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSPQ_SODGM
Sequence: MIASKFGIGQQVRHKLLGYLGVIIDVDPEYSLEKPSLDDIAADDSLRTAPWYHVVMEDEEGKPVHIYLAEAQLGYESFPVHPEQPTLDELAESIRLQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 2A5B_RABIT
Sequence: METKLPPASTPTSPSSPGLSPVPPADKVDGFSRRSLRRARPRRSHSSSQFRYQSNQQELTPLPLLKDVPASELHDLLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGSTRGVLIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEVEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKARERQELWQGLEELRLRRLQGTQGTQGAREAPLQRFVPQVAATGGQS
What is the function of this protein?
As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation.  The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform, PP2A B subunit isoform B'-alpha, PP2A B subunit isoform B'-beta, PP2A B subunit isoform B56-beta, PP2A B subunit isoform PR61-beta, PP2A B subunit isoform R5-beta.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KCNV1_HUMAN
Sequence: MPSSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation.  Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.
What are the official names of this protein?
Potassium voltage-gated channel subfamily V member 1, Neuronal potassium channel alpha subunit HNKA, Voltage-gated potassium channel subunit Kv8.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2.
Protein: ISCR_ECOUT
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: NUOH_ECO24
Sequence: MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVPVSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YIDD_DEIRA
Sequence: MSAAPLVRAVRWYQRVLSPRKPAPTCRFSPTCSEYAAQALDRHGALKGGWLALWRVLRCNPLVPGGFDPVPEHFPARHPRPQGSPPTDHPPTDQPS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CGR1_CRYNJ
Sequence: MSAEPSSSAQASAPTVVSVAPSKNGRTPGKAHKSAKTALRRSYISPSVKTPFEKRMEKEKAQQAAKQLEKELKEEKENERQRKVNIIKERRARKEEKQREEELRAKMSAKKLQRMKKREGRSKKING
What is the function of this protein?
Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
What are the official names of this protein?
rRNA-processing protein CGR1.
What is the protein family that this protein belongs to?
Belongs to the CGR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PQN25_CAEEL
Sequence: MEETCSESPKESNIISFIWHKLLKRVPPPIMICLFFLLLQIFVISVVSQCPPGLTPLFSNSNFNQPLTCTPQDACSCYSSSGSSRFGTICQYASTYNNYICCYSTNTQCGSNSSPQVSASGQVVTCSTNTQCASGYTCNNGACCPNTNSNTCSSNGNNGCLAGQTMVNGQCYNSVNIGSACQSTQQCLGGSQCQNNICQCYSGYVNVNQQCVISNGLNCQLGTVSYNSQCITLASPGQNCQTSSQCIDNSVCMNQMCTCNNNYRLVYGYCVPITSSICQQTQTLVNNQCVLLSIVGETCIANQQCVGGAMCNSGTCQCTNGATAMYGYCISSSSSSCNSNQVSINGMCYNTVQVGGSCSFSQQCLNNAVCTNNICVSTFCSVSCSTNQVCISNQCYNYVSIGSQCVGSQQCLSNSQCISSICQCPQGTQQSNGVCTGNNNNNNQCQPNQVLINNQCYNTVSIGFQCQFPQQCLGNSQCMNSMCQCPTGSTNVNGYCQGGSNGQCNSNQVLINNQCYNTVSIGFQCQFAQQCLGNSQCLNSICQCPSGSSNVNGYCQGGSNGQCNSNQVYYNNQCYNTVPIGSQCQITQQCLGNSQCMNSFCQCPSGTTNVNNFCTTSSSSSNLCSAGQTVQLDSSNQPINCLVSTCPNNSFCQYSSSGQRYVCCRSTSGKKK
What are the official names of this protein?
Prion-like-(Q/N-rich) domain-bearing protein 25, Glutamine/asparagine-rich protein pqn-25.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HEM6_ECOL5
Sequence: MKPDAHQVKQFLLNLQDTICQQLSAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVYPRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAS_CAPHI
Sequence: MGLRPDGIIGHSLGEVARAYYNGRISQEEAILSAY
What is the function of this protein?
This fragment is from the acyltransferase domain of the fatty acid synthetase.
What are the official names of this protein?
Fatty acid synthase.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome.
Protein: FABZ_RUEPO
Sequence: MTTETKSADIQLIQRILPHRYPFLLVDKVVEIDGYSSAVGIKNVTMNEPHFQGHFPGTPIMPGVTIVEAMAQTAGVMLGVGMDIIDSELLIYFMNIDNCKFRRKVVPGDVMKMHVETLRGKMGGKIFKFRGTATVEGEVAAQAEFSAYVDLTGEKST
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAPKA_ORYSJ
Sequence: MDRAALTVGPGMDMPIMHDGDRYELVRDIGSGNFGVARLMRSRADGQLVAVKYIERGDKIDENVQREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQVCHRDLKLENTLLDGSTAPRLKICDFGYSKSSVLHSQPKSTVGTPAYIAPEVLLKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPDEPKNFRKTIQRILGVQYSIPDYVHISPECRDLIARIFVANPATRISIPEIRNHPWFLKNLPADLMDDSKMSSQYEEPEQPMQSMDEIMQILAEATIPAAGSGGINQFLNDGLDLDDDMEDLDSDPDLDVESSGEIVYAM
What is the function of this protein?
May play a role in signal transduction of hyperosmotic response.  Together with PYL10, PP2C53 and SAPK8, may form an abscisic acid (ABA) signaling module involved in stress response (PubMed:26491145).  Together with PYL3 and PP2C50, may form an ABA signaling module involved in stress response (PubMed:28827170).
What are the official names of this protein?
Serine/threonine-protein kinase SAPK10, Osmotic stress/abscisic acid-activated protein kinase 10, stress-activated protein kinase 10, OsSAPK10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: BGBP_PENMO
Sequence: MKGFVASVVLLACGALAADIVEPEDCTSFPCMIFEDNFDYLDNDIWEHEITMSGGGNWEFQAYVNNRSISYTRDSTLFIKPDLTSNWKGEDFLSSGTLDLWGMNGRGDVCTGNSYYGCSRVGSSSNIINPVTSARLRTMSNFAFRYGRLEVRAKMPRGDWLWPAIWMLPRNWPYGLWPASGEIDILESRGNDDFGTLGNQYGGTTLHWGPFWPYNFFEKTHAEYSANTGSFADDFHVWRLDWTKDNMEFYVDDVLQLTVDPGTSFWDFAGMGPFFDNPWAAGAKMAPFDQKFYLILNVAVGGTNGFFPDGIASKPWSNLSPTAFLDFWNARDEWLPSWKAGEDRISEGAAMQVDYVRVWKMESTEQ
What is the function of this protein?
Binds to beta-1,3-glucan.  May play a role in recognition of microorganisms and in activation of the prophenoloxidase cascade.
What are the official names of this protein?
Beta-1,3-glucan-binding protein, GBP.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
What are the subcellular locations of this protein?
Secreted.