PharMolix/UniProtQA huggingface dataset:
Protein: CH10_BRUAB
Sequence: MADIKFRPLHDRVVVRRVESEAKTAGGIIIPDTAKEKPQEGEVVAAGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKIGGEDLLIMKESDILGIVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XB32_ARATH
Sequence: MRFLSLVGNSFGCSASGERLVSAARDGDLQEAKALLDYNPRLARYSTFGVRNSPLHYSAAQGHHEIVSLLVESGVDINLRNYRGQTALMQACQHGHWEVVLILILFGANIHRSDYLNGGTALHLAALNGHPRCIRILLSEYIPSVPNCWSLLKNKKTSVAGFDSSVLHEVINRAADGGITPLHVAALNGHIETVQLLLDLGASVTQVTVEDGTTIDLIGAGSTALHYASCGGNTQCCQLLISKGACLAAVNSNGWTPMMVARSWHRNWLEEILNPTTEQPQLHLPNVPSPFLCLPLMSIVNIAQECGWRENDCLTPCRDPCAVCLERKCTVAADGCAHEFCTNCALYLSTTSITSSKTSNVTPGSVPCPLCRNGIVSFTKLPHTTATTRTSTSSRTSISLSFCTCSSDVLDTALLTNPHYSCKPVVSRTGSRTPQSARSSAFRSLSCRRFPPSLCLGGSDVDEPRSRLIGGSYSRSGVGFRRSTSQVEGKRSWFSALNHCVTTGGSAC
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of ACC synthases (ACS).  Negatively regulates ethylene biosynthesis probably via ubiquitin-dependent degradation of ACS4 and ACS7 enzymes.  Regulates lateral root formation and development by controlling ethylene production which inhibits lateral root formation at high concentration.
What are the official names of this protein?
E3 ubiquitin-protein ligase XBAT32, Ankyrin repeat domain and RING finger-containing protein XBAT32, Protein XB3 homolog 2, RING-type E3 ubiquitin transferase XBAT32.
Protein: NAMPT_MYCPN
Sequence: MVQTPSEINTHLKHLLACDAYKLSHRLMYPNDTTNLYSCLTARGGRGGFPNFVWNHEFAKKIILEVFGNFCDSVLAVQNDPGLAQALTDKVTTVFGDPQFGLEFTQHICYLANFLKQHHQLPLTVKIHQSSEGLAFRTPLVTITGSDQMVPELVWLVNYFETVLLENIWLYQTTLTVAQSLKLLLERYANETADNTEFTHFQCHDFSMRGMSSLQSALYVANAHLQYFSGSDTILGGVAAKSILASEHSVMCADGQEGELNTFKRLLEQFPNKNLSLVIDSYDMWHVLDNILPQLKDLVLQRQEKLYLRPDSGNFETLICQGKRFNPEDKTTWGVIDYLDYHFGSTVNQKGYKVLNQKLGIVYGDGITYERIEYILEQLKQRGFCSSNIVFGVGSTTYQNLNRDTLGFVYKLTAIKKGNTWHDVTKSPITDPTKQSIGGRFDNPNLIQVYG
What is the function of this protein?
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD.
What are the official names of this protein?
Nicotinamide phosphoribosyltransferase, NAmPRTase, NMPRT, Nampt.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: CLPP_STAPU
Sequence: MPIGVPRVPFRLPGEEEAVWVDVYNRLYRERLLFLGQNVDDEIANQLIGIMIYLNGEDESKDMYMYINSPGGAVLAGISVYDAMQFVVPDVHTICMGLAASMGSFILTGGEITKRIALPHARVMIHQPASSYYDGQAGECMMEAEEVLKLRDCITKVYVQRTGKPAWLISEDMERDVFMSAKEAQEYGIVDLVASDTNSTT
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RPIA_RHIEC
Sequence: MDAREMKIKAAEAALAHVESGMRLGIGTGSTAEEFVRLLAEKVAGGFQVEGVPTSERTARLCVELGVPLKSLDELPALDLTVDGADEVDPALRLIKGGGGALLREKIVAAASQRMIVIADESKLVETLGAFALPIEVNPFGLVSTRIAIEKVAARLGLSGELNLRQSGDGEFTTDGGHHIIDASFGRIPDAEALSSELNSIPGVVEHGLFINMAALAIIAGPAGARTLQANR
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RL3_ARCFU
Sequence: MKYHRPRRGSLAFSPRKRAKSIVPRIRAWPECDRVRMQGFAGYKAGMTHVVMIDDRKNSPTYGEEVVVPVTVIETPPMKVAAVRVYKKTQYGMQIAAEVWSNNLDDFLDRRLNLPKKEPDVEKLKAAVENGASEVRVVTYTQPYLITGVPKKVPDVMEHRIGGNVEEALDYAISKLGKEISVSEVFDEGAIIDVIAVTKGKGFQGPVKRWGVITLDAKHARSSKHRRVGNLGPWNPHHVRWTVPQAGQMGFHQRTEYNKRLIKIGENGEEITPKGGFLHYGVIRTQYVLVTGSVPGPVKRLIRMRDAIRPPKAHFDGVNIVYVSTTSKQGR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y1178_STRP6
Sequence: MTTKKAYMYVLECADKTLYTGYTTDLKKRLATHNAGKGAKYTRYRLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH
What are the official names of this protein?
UPF0213 protein M6_Spy1178.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: CRLS1_DROME
Sequence: MLPAIIFRQVQRPLHHGAATLEHVLGVGGSSFVNCLNRYAAATGFIRISFLDIKRRRNYELARLRLYADEKKQSLHLRTLQGRHLLQGVIERKNFLVDDIREARHKVQERVREKIDEIREERENIMTIPNMLTISRAVLSPYIGYVIVQGDFTLGMSLLAFAGITDLLDGQIARRWPSQASKFGSFLDPMADKLLMGSLVISLCYTDLLPMWLMGIVVFRDVFLLGAGFVIRYISLPPPKTFSRYFDATHVTAQLEPTLLSKINTGVQLATIGLSLGAPIWNYLDHPALQGLWYLTGLTTAATALSYVMNRHNTFKIIQKKT
What is the function of this protein?
Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG).  CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
What are the official names of this protein?
Probable cardiolipin synthase (CMP-forming), CLS.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ODFP4_MOUSE
Sequence: MEPDLNEEESERIRTSRNRRSLEHRRNSLLPFQWKATNNSRWMAQVVASEFSLVAFLLLLVMVFSKKWLYPSKSRFHQRYPQNVTKRVYTSIHSMSTGLLYICVSKSCPSSDNGEDNFKMWTIHPVFGVAKISFTLAIGLGFVLTTWLHLPYLPCLQRMPFFGLIGIILSFCEVTLIFLTLLLFPVNLWIYELRKNISVPIGWSYFIGWLVLILYFTCGILCYLNHKNYWSLIMSSTTINTACSSLGPESLVSPSQTPSSQENSQESPKDDQKPSSPDKVVSPPQPDTTG
What is the function of this protein?
Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.
What are the official names of this protein?
Outer dense fiber protein 4, Outer dense fiber of sperm tails protein 4, Testis-specific protein oppo 1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MUTS_CHRVO
Sequence: MAAIPTPRLHRGVTHLSRQTKSRARHPMSTPQHTPMMQQYLALKREHADKLLFYRMGDFYELFYEDAEKASRLLDITLTARGASAGNPIKMAGIPYHAAEGYLARLVKMGESVAIAEQIGDPALAKGPVERKVVRIVTPGTLTDAALLDDKRDNLVLAVNMVKGVLGLAWLSLASGEFKIMQASVEDLASELERLKPAELVIPDDTGLAAFEGISTPKKKLPPWQFDIESSKLALTRHFGTRDLAGFGADTLPVAVGAAGALLEYVKSTQGVNPAHISALSVEDAGELIRMDAATRRNLELTETIRGEASPTLASLLDTCATSMGSRLLGHWLHHPMRNHGKLARRHGAVRALLSRYQDVHAELDQVSDIERITSRVALRSARPRDLSALRDSLTALSGVKALAASLDSELLNELAGVLPTESPVQKMLAAAILPEPATFLRDGGVINDGFSPVLDELRAIQTDCGDFLLKLEAREKERTGITTLKVEFNRVHGFYIEVSKAQSDKVPDDYRRRQTLKNAERYITPELKEFEDKALTAQDRALALEKQLYEALLDQLAPHIAELKLIAQAVAALDVLSAFAQRAAIGNYAEPQFVPEPKLDIVAGRHPVVEAEVERFIANDTRLSAERKLLLITGPNMGGKSTYMRQNALITLLAHVGSFVPADSAVIGPIDRIFTRIGASDDLAGGRSTFMVEMTETANILNNASEHSLVLMDEVGRGTSTFDGLALAWAIARALIEKNRAYTLFATHYFELTTLAGEYPAVANVHLSAVEHKDRIVFLHHVEDGPASQSYGLAVAQLAGVPAKVIRDARRHLAELENQSAARVQPDLFSAPAPASEPELSPAMDRLQEIDPDVLSPRQALEILYELKKLAD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DAPB_BURCM
Sequence: MKIAIAGASGRMGRMLIEAVLNDSDAQLVGALDRADSPFLGQDAGAFLGKETGVKLTDDLDAVFAQADYLIDFTRPEGTIAHVAAALRHEVKLVIGTTGFTAEQKAELQAAAARIGIVFAANMSVGVNVTLKLLEFAAKHFSHGYDIEIIEAHHRHKVDAPSGTALMMGEAVAGALGRSLEDCAVYGRQGVTGERDPSTIGFAAVRGGDIVGDHTVLFAGIGERIEITHKSSSRVSYAQGALRAVRFLSARGAGLFDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A2MG_XYLFT
Sequence: MRDRVAMMLRPLVRGWIPRAVLLLTVAFSFGCNRNHNGQLPQSSGEPVAVAKEPVKGFVLVRAYPDQHDGELALALEFSQPLAATQEFDTLVRLEQGSGNHDGGWSLSDDAKTLRYPYVEADKHYTVLISGDLLAATGSRLGKSRKEPVYTGELDPVVGFASRGSILPARGSRGVPVVSVNVPEVDVEFMRVREKALPAFLARYHKAGQRSSWELSNQGNSRKRLSELADPVYVTRFVLDGKKNERALTYLPIQNIRELREPGLYFAVMKPTGSFSDAFETAFFSVSNIGLHARAYKDKLFVHTASLRSGNPYKQVDLLVLDAKGETVLQGATDDNGNALLNYTLNAGHVLVSRNGRDISILPFNQPALDLSEFAVAGRENPWFDVFAWSGRDLYRPGEMLRISALLRDRDGKPVKPQPVFLRLKQPDGKTFRETRLQPAEQGYLEFTQKIPSDAPTGRWRVEFRTDPASKEAVQGLAVRVEEFLPERMKLELSSAQPVLRAKAPFTLTADAAYLYGAPAAGNRFTANLAVAVEQHPLDNMPGWFFGDATLQLPRGAKETIDITLGADGHLVHDIVLPEEAKPVSPMAVVVSGSVYESGGRPVTRSLKRVLWPADALVGVRPLFDVASGADANGMARFELTRVGVDGKPQSAKGLKATLVRELRDYHWRYSDGRWDYDFTRRFENKETRTVDISSSHTTTLSLPVEWGDYWLEVFDPVTGLTMRYPFRAGWSWGDDNRGLDARPDKVKLALDKTSYRAGDTLKVTITPPHPGKGLLLVESDKPLYVQAIDANPSTTLEIPVTADWERHDVYVTALVFRGGSASNNTTPARAVGEAYVPMQRKERRVAVGLVVPKQVRPAQSLPVTVSVPELAGKQAHVTISAVDAGILNITGFPVPDAAAHFFAQRRLSVDAYDIYGRVIESFEGGTGRLKFGGDMALPPLPQAKRPTARSQTVDLFSGAVKLDAKGNAHIQLPVPDFNGALRVSALVYSDTRYGQRDAETVVRAPILAEASMPRVMAPGDRSTVTVDVQNFTGKQGKFAVKVEGVGPLVVAEAGRSVTLGIDGKTTLNFPLRALEGNSVAQVRVRVEGNGSKAERHYDLPVRAVWPQGLRTQAHVLNVLAPIAFDPALAKGLMPDSVNARLSVSTLAPIPFASVLQGVFEYPYGCAEQTASKGYAALWLDDATIRSLGIQGVTPAQRLERLEGALGRLASLQTTNGHFSMWGGNSDVNPVLTPYIAGFLLDAKDAGFAVSDAVLQKALNRLSEDLLSGAHLFYGNDQSEALMFAHQAWSGYVLARVNRAPLGTLRTLYDNERGKAVSGLSLVHLGVALSLQGDRKRGEAAIEAGFAKSEGGRPEVFGDYGSVIRDNALMIALVRAHGLAKPAYEARVMALGRDLQARRRSGWLWLSTQEQVALAQLGRALLVDQKKQVSGTLYVGKQREDIAASRLIGRSFDAAALARGVRFVPQGDVPLYASFEVAGIPRQAPVSDDSQLLVVRRWYTVDGKPWTPGPLKEGQALIVRVSVTSKQNMPDALLTDLLPAGLEIENFNLGETRQWADVTVDGIALSERADAADIKHEEFRDDRYVAMLQLTGGRTANLFYLVRAVTPGSYNVPPSLVEDMYRPALRGTGRVAPAMVTVVQP
What is the function of this protein?
Protects the bacterial cell from host peptidases.
What are the official names of this protein?
Alpha-2-macroglobulin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: EFP_PSET1
Sequence: MANYSTNEFKGGLKIMMDGEPSSIIENEMVKPGKGQAFNRVRIRKLISGKVLEKTFKSGESVEGADVMDTDLAYLYTDGEFWHFMNNETFEQIAADEKALGDAGKWLVENDVCTITLWNGNPIVVTPPNFVELEITETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQIGEVIKVDTRNGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_CLOPS
Sequence: MRIAVDGMGGDHSPSAVVEGCVQALEEFKDIEIYITGPEDLLKEAFSKFKYDKERVIFIDAKEVISTNEHPAMAVKKKKDSSLVKALRLVKDNQCEAVISAGSTGAFLTGCTLIVGRIKGVERPALAPVMPGKNGPFMIIDAGANVDSKPSYLVQFAKMGEVYFKSVMDVNNPKVGLVNIGEEEEKGNDLTKATYKLLKEEKDINFIGNVEPREVSTGDVDVLVCDGFVGNTVLKMYEGVASTILSMIKSEVKSSFLAKLGVPFLAPALMNLKKKMDYKEYGGAPFLGVKGICVKAHGSSDAKAFKNAIRQARKFHENDLIGKLSEEITKKSFDNQKKF
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MPT51_MYCTO
Sequence: MKGRSALLRALWIAALSFGLGGVAVAAEPTAKAAPYENLMVPSPSMGRDIPVAFLAGGPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGKGISVVAPAGGAYSMYTNWEQDGSKQWDTFLSAELPDWLAANRGLAPGGHAAVGAAQGGYGAMALAAFHPDRFGFAGSMSGFLYPSNTTTNGAIAAGMQQFGGVDTNGMWGAPQLGRWKWHDPWVHASLLAQNNTRVWVWSPTNPGASDPAAMIGQAAEAMGNSRMFYNQYRSVGGHNGHFDFPASGDNGWGSWAPQLGAMSGDIVGAIR
What is the function of this protein?
May have a role in host tissue attachment, whereby ligands may include the serum protein fibronectin and small sugars.
What are the official names of this protein?
MPT51/MPB51 antigen.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial A85 antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPPL_CYAPA
Sequence: MPIGYPLVKAMDKDRFISYFLINNALLNERVIFLCNYEDATDESIYIGMLLYLESENSQKPVSFYINSSITFPNLCFGLYDTILQIKADIVTICLGLAGGMSSLILAAGTKGQRFALPNSRIMMQEPLIDGGVNGQATDLAIEAKELMDTKEILINLYHERTGQPKPVIEKDLQRPRYFSAQAAKEYGFIDSLLMASNG
What is the function of this protein?
Has lost the two conserved residues (Ser and His) proposed to be part of the active site.  Therefore it could be inactive.
What are the official names of this protein?
Putative ATP-dependent Clp protease proteolytic subunit-like, Endopeptidase Clp-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: CCMA_GRABC
Sequence: MQGCRQRESNKICTRDGPGGMLTARGLAVFRAERLVFRDLDFSLVPATLRPAGEGAPDAVTLIGPNGSGKSTLLRLLAGFVRPAVGTVWWQEEPLPADPADRARIVTYIGHQDAVKPGLTAAENLLFDASWHPRGRRREAILNALEAVGLSALSALPGRMLSAGQKRRLALSRLMLRETPVWLLDEPTLGLDDASIALFGDMLRAHRARGGVVMAATHVPLPLPGAGVLSLHPHALAAQTGQAAIEGAGDEWAGDEWG
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DARG_MYCTU
Sequence: MITYGSGDLLRADTEALVNTVNCVGVMGKGIALQFKRRYPEMFTAYEKACKRGEVTIGKMFVVDTGQLDGPKHIINFPTKKHWRAPSKLAYIDAGLIDLIRVIRELNIASVAVPPLGVGNGGLDWEDVEQRLVSAFQQLPDVDAVIYPPSGGSRAIEGVEGLRMTWGRAVILEAMRRYLQQRRAMEPWEDPAGISHLEIQKLMYFANEADPDLALDFTPGRYGPYSERVRHLLQGMEGAFTVGLGDGTARVLANQPISLTTKGTDAITDYLATDAAADRVSAAVDTVLRVIEGFEGPYGVELLASTHWVATREGAKEPATAAAAVRKWTKRKGRIYSDDRIGVALDRILMTA
What is the function of this protein?
Antitoxin component of a hybrid type II/IV toxin-antitoxin (TA) system.  De-ADP-ribosylates DNA (probably) modified on thymidine by its cognate toxin DarT, which neutralizes the activity of DarT (PubMed:27939941).  Experiments in which DarG levels are depleted lead to cell death; expression of wild-type DarG protein from M. tuberculosis or T. aquaticus restores growth.  Cells depleted of DarG are more sensitive to bedaquilline (targets respiration), DNA-damaging drugs (mitomycin C, netropsin) and transcription-targeted drugs (rifabutin and rifampicin).  When depleted, a DNA-damage response is induced and mutability is increased (PubMed:32634279).  In E. coli the macrodomain alone neutralizes DarT toxin from non-cognate T. aquaticus.  The same domain de-ADP-ribosylates genomic DNA (PubMed:34408320).
What are the official names of this protein?
DNA ADP-ribosyl glycohydrolase, DarG, Antitoxin DarG.
What is the protein family that this protein belongs to?
Belongs to the DarG ADP-ribosyl glycohydrolase family.
Protein: OST4_DROPS
Sequence: MITDVQLAIFSNVLGVFLFLLVVAYHYINANTGKSSPKAK
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the OST4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: AN32E_CHICK
Sequence: MEMKKRINLELRNQAPEEVTELVLDNCKSSNGEIEGLNDSFKELEFLSMANVQLTSLAKLPTLSKLRKLELSDNIISGGLEVLAERCPNLTYLNLSGNKIKDLGTVEALQNLKNLKSLDLFNCEITNLEDYRDSIFDLLQQITYLDGFDQEDNEAPDSEDDDDEGDEDDNDEDEDEAGPPGEYEEEDDEDDGGSDLGEGEEEEEVGLSYLMKEEIQDEDDDDDYVEEGGDEEEEAEGIRGEKRKRDPEDEGEEEDD
What is the function of this protein?
Histone chaperone that specifically mediates the genome-wide removal of histone H2A. Z/H2AZ1 from the nucleosome: removes H2A. Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions.  Not involved in deposition of H2A. Z/H2AZ1 in the nucleosome.  May stabilize the evicted H2A. Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state.  Inhibits activity of protein phosphatase 2A (PP2A).  Does not inhibit protein phosphatase 1.  May play a role in cerebellar development and synaptogenesis (By similarity).
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32 family member E.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DD19A_HUMAN
Sequence: MATDSWALAVDEQEAAVKSMTNLQIKEEKVKADTNGIIKTSTTAEKTDEEEKEDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAMLSRVEPSDRYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEIEKIAN
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA export from the nucleus.  Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins.
What are the official names of this protein?
ATP-dependent RNA helicase DDX19A, DDX19-like protein, DEAD box protein 19A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Note=Associates with the nuclear pore complex cytoplasmic fibrils.
Protein: RS19_RIPO1
Sequence: MGRSLKKGPFVSDSLLTKIEKLNEKGDKQVIKTWSRASTILPQMVGHTIAVHNGKQHVPVYVSEQMVGHKLGEFAPTRTFRGHAKSDKKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL11_ECO27
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NODK_BRASP
Sequence: MARLFIAVIAIQGASKMHRTEVDLVPVGCVLDELSRIDGLPRDATAPILILDEAEPLHAADRLRAIGSLPWDVRACFGHGIGRKDAREMRDRLAANEAAIPIRSALARSARRAERGCRMPAHFRLITGSANSEFLT
What are the official names of this protein?
Nodulation protein K.
Protein: PSBF_AGARO
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: IL1RA_BOVIN
Sequence: MDIYIHGYLICLLLFLFRSETACHPLGKRRCEMQAFRIWDVNQKIFYLRNNQLVAGYLQGPNTKLEEKIDVVPIEPHTMFLGIHGGKLCLACVKSGDEIKLKLEAVNITDLNQNREQDKRFAFIRFDNGPTTSFESAACPGWFLCTSLEADQPVGLTNMPTEALKVTKFYFQQD
What is the function of this protein?
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A.  Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
What are the official names of this protein?
Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, IL1 inhibitor.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Secreted.