PharMolix/UniProtQA huggingface dataset:
Protein: RIPK_ARATH
Sequence: MAVKKKVSWRSLIVGCLGDPETLMASSKKPKRKNDVIKKQSSFQRLSILDMSNPSSNTLSEDLSISLAGSDLHVFTLAELKVITQSFSSTNFLGEGGFGPVHKGFIDDKLRPGLKAQPVAVKLLDLEGLQGHREWLTEVMFLGQLKHKNLVKLIGYCCEEEHRTLVYEFMPRGSLENQLFRRYSASLPWSTRMKIAHGAATGLQFLHEAENPVIYRDFKASNILLDSDYTAKLSDFGLAKDGPEGDDTHVSTRVMGTQGYAAPEYIMTGHLTARSDVYSFGVVLLELLTGRRSVDKKRSSREQNLVDWARPMLNDPRKLSRIMDPRLEGQYSETGARKAATLAYQCLSHRPKNRPCMSAVVSILNDLKDYNDIPMGTFTYTVPNTPDNKEDDGRVGNKPRKSSHHHHHQQQQSNHPRSSPSPTTKSPSPTAKSPRNSTENHRRTLRNGVNSPLRSEAGGERY
What is the function of this protein?
Serine/threonine-protein kinase involved in disease resistance.  During Pseudomonas syringae infection, and in response to the bacterial effectors AvrB and AvrRpm1, RIPK phosphorylates the host target RIN4, which subsequently activates RPM1-dependent effector-triggered immunity (ETI) (PubMed:21320696, PubMed:25625821).  Seems to act as negative regulator of plant basal defense responses and may play a role in pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) (PubMed:21320696).  Required for the bacterial XopAC/AvrAC effector-triggered immunity against Xanthomonas campestris (PubMed:23951354).
What are the official names of this protein?
Serine/threonine-protein kinase RIPK, ACIK1A/PBL14, ACRE protein ortholog 264A, AtACRE264a, PBS1-like protein 14, RPM1-induced protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: P2A_SBMVA
Sequence: MYHPGRSPSFLITLANVICAAILFDIHTGGYQPGSLIPIVAWMTPFVTLLWLSASFATYLYKYVRTRLLPEEKVARVYYTAQSAPYFDPALGVMMQFAPSHGGASIEVQVNPSWISLLGGSLKINGDDASNESAVLGSFYSSVKPGDEPASLVAIKSGPQTIGFGCRTKIDGDDCLFTANHVWNNSMRPTALAKRGKQVAIEDWETPLSCDHKMLDFVVVRVPKHVWSKLGVKATQLVCPSDKDAVTCYGGSSSDNLLSGTGVCSKVDFSWKLTHSCPTAAGWSGTPIYSSRGVVGMHVGFEDIGKLNRGVNAFYVSNYLLRSQETLPPELSVIEIPFEDVETRSYEFIEVEIKGRGKAKLGKREFAWIPESGKYWADDDDDSLPPPPKVVDGKMVWSSAQETVAEPLNYQRAAGSRPLPPFLNLQATTSKKEKQPLQEECPLDLLGSRLASLESCVEKILQMKSLELLGSSQNCQTSPGPSEAPKQSFTPCYSKQESLIPLESQGILKELVKTSLSATPPPNPVTVSVEKPGPSTQSTKKSARRRNRRKSTRKPVQESPSPASPQPTKTSLRGI
What is the function of this protein?
Covalently attached to the 5' extremity of the genomic and subgenomic RNAs.  It may serve as a primer for the replicase.
What are the official names of this protein?
Polyprotein P2A.
What are the subcellular locations of this protein?
[Polyprotein P2A]: Host membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [N-terminal protein]: Host membrane; Multi-pass membrane protein.
Protein: PEPT_SHIB3
Sequence: MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEEMGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNIPHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLAGMKGTVERADMHYIIRDFDRKQFEARKCKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAQRK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANO4_HUMAN
Sequence: MEASSSGITNGKTKVFHPEGGVDLQGYQLDMQILPDGPKSDVDFSEILNAIQEMAKDVNILFDELEAVSSPCKDDDSLLHPGNLTSTSDDASRLEAGGETVPERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKAHHNEWP
What is the function of this protein?
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity).  Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity).
What are the official names of this protein?
Anoctamin-4, Transmembrane protein 16D.
What is the protein family that this protein belongs to?
Belongs to the anoctamin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Shows an intracellular localization.
Protein: YHDW_BACSU
Sequence: MYIIAHRGASGYAPENTIAAFDLAVKMNADMIELDVQLTKDRQIVVIHDDRVDRTTNGSGFVKDFTLEELQKLDAGSWYGPAFQGERIPTLEAVLKRYHKKIGLLIELKGHPSQVGIEEEVGQLLGQFSFSINNIVQSFQFRSVQRFRELYPSIPTAVITRPNFGMLSRNQMKAFRSFANYVNIKHTRLNRLMIGSINKNGLNIFAWTVNNQKTAAKLQAMGVDGIVTDYPDFIIKDGKHENI
What is the function of this protein?
Glycerophosphodiester phosphodiesterase hydrolyzes glycerophosphodiesters into glycerol-3-phosphate (G3P) and the corresponding alcohol.
What are the official names of this protein?
Putative glycerophosphodiester phosphodiesterase YhdW, Glycerophosphoryl diester phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Protein: PYF4_PENMO
Sequence: YSLRARPRF
What is the function of this protein?
May act as a neurotransmitter, neuromodulator or neurohormone.
What are the official names of this protein?
Peptide tyrosine phenylalanine 4, Pem-PYF4.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBJ_THEVL
Sequence: MMSEGGRIPLWIVATVAGMGVIVIVGLFFYGAYAGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: UFC1_ORYSI
Sequence: MEGWDKGTKSVVGEIPLLSTRAGPRDGEAWRQRLKEEYRALIAYTSVNKSKDNDWFRISAANPEGTRWEGTCWYVHNLRRYEFPLQFDIPVAYPQVAPEIELPTLDGKTHKMYRGGKICLTVHFKPLWAKNCPRFGIAHALCLGLAPWLAAEVPILVDSGMVKHKDDEAAPADAAAAASGSAAAS
What is the function of this protein?
E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: SYT_SYNY3
Sequence: MAKTVVSPDTIALPRTSESEQLKKIRHTTSHVMAMAVQKLFPKAQVTIGPWTETGFYYDFDVAEPFTEADLKAIKKEMVKIINKKLPVIREEISREEAKQRIESIQEPYKLEILDSIHEPITVYHLGDQWWDLCAGPHLESTADINPKAIALESVAGAYWRGDANKAQLQRIYGTAWETPEQLAEYQRRKEEALKRDHRKLGKELGLFIFADPVGPGLPLWTPKGTIIRTILEDFLKQEQIKRGYLPVVTPHIARVDLFKQSGHWQKYQEDMFPMMAESPEEAAQEMGFVLKPMNCPFHIQIYKSELRSYRDLPLRLAEFGTVYRYEQSGELGGLTRVRGFTVDDSHLFVTPDQLDEEFLSVVDLILTVFKSLQLKNFKARLSFRDPESDKYIGSDEAWEKAQGAIRRAVQELEMDYFEAPGEAAFYGPKLDFIFQDALEREWQLGTVQVDYNLPERFDLEYIAADGSRQRPVMIHRAPFGSLERLIGILIEEYAGDFPLWLAPIQVRLLAVSDEFLPFAQSIVQQMQSLGLRAEVDTSGDRLGKMIRNAEKQKIPVMAVIGAKEVEANALNIRTRASGELGEIPVTEVLEKLQATVTNHDTW
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP76_CAEEL
Sequence: MDSDWESTFEFVSETGQIKKRGSKTSELKQNETTDAVVVNNEKVKKRRNSKDSHIVLAKEIFAVAFFSLGMSCLLMADVSTFLWGINNPNSQQSKSIGSNIDQMSSEEFQQKVHDYMSEIQRTGRDKRPSRRFVDSARFYILSEIEPIELALRREWIPDHSFFEGVQEFIRGMEWENTFEEELFVRGVPNFDHDFESEEMTLKTTLDGKNYNNQFLNLGRKEIIGKHHSMEYFISGRTLIRLVKNEGQELSRTEYYLKHGDLHVYDKRGNLDCTRVYRSPTISPMLQSKIRQF
What are the official names of this protein?
Uncharacterized protein B0228.6.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ANCA_ACET2
Sequence: MKRIKRILAVLTIFALLATINAFTFVSLAQTNTIEIIIGNVKARPGDRIEVPVSLKNVPDKGIVSSDFVIEYDSKLFKVIELKAGDIVENPSESFSYNVVEKDEIIAVLYLEETGLGIEAIRTDGVFFTIVMEVSKDVKPGISPIKFESFGATADNDMNEMTPKLVEGKVEIIEASAPEATPTPGSTAGSGAGGGTGSSGSGQPSATPTPTATEKPSTTPKTTEQPHEDIPQSGGTGEHAPFLKGYPGGLFKPENNITRAEAAVIFAKLLGADENSAGKNSSITFKDLKDSHWAAWAIKYVTEQNLFGGYPDGTFMPDKSITRAEFATVTYKFLEKLGKIEQGTDVKTQLKDIEGHWAQKYIETLVAKGYIKGYPDETFRPQASIKRAESVALINRSLERGPLNGAVLEFTDVPVNYWAYKDIAEGVIYHSYKIDENGQEVMVEKLD
What is the function of this protein?
Anchors the cellulosome to the cell surface by binding the duplicated segment that is present at the C-terminal end of CipA.
What are the official names of this protein?
Cellulosome-anchoring protein.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer.
Protein: RST3_AVESA
Sequence: MATSSAVLFLLLAVFAAGASAATFRITNNCGFTVWPAGIPVGGGFQLNSKQSSNINVPAGTSAGRIWGRTGCSFNNGRGSCATGDCAGALSCTLSGQPATLAEYTIGGSQDFYDISVIDGYNLAMDFSCSTGVALKCRDSGCPDAYHHPNDVATHACNGNSNYQITFCP
What is the function of this protein?
Associated with resistance against stem rust fungi.
What are the official names of this protein?
Thaumatin-like pathogenesis-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
Protein: KSL7_ORYSI
Sequence: MMLLGSPSSGGYGGKFAGASPAGGTTTMAPSAKQPSSRAPPPGITGGRNDLRILSPAAAAAAVGGLEMKKPEAEGIAESLQATHRKELEASIRKQLQGVELSPSPYDTAWVAMVPLRGSSHNPSFPQCVDWILENQWDDGSWSIDGSISTANKDVLSSTLACVLALNKWNVGREHIRRGLSFIGRNFSIAMDDQAVAPIGFGITFPAMLTLANGSGLEVPVRQNDIDSLNHLREMKIQREAGNHSRGRKAYMAYLAEGFGNLLEWDEIMMFQRKNGSLFNCPSSTAGALANYHDDKALQYLQSLVNKFDGVVPTLYPLNIYCQLSMVDALENMGISQYFASEIKSILDMTYSSWLGRDEEIMLDVTTCAMAFRLLRMNGYDVSSDELSHVAGASGFRDSLQGYLNDRKSVLEVYKTSKHSISENDLILDSIGSWSGSLLKEMLCSNGIQGTPGREEIEFALKYPFYSTLERLVHRKNIVLFDAKGSQMLKTECMPVHDSQDFLALAVDDFCISQSNYQNELNYLESWVKDNRLDQLHFARQKITYCYLSGAATTFRPEMGYARTSWARTAWLTAVIDDLFDVGGLEQEQENLLALMEKWEEPGEDEYYSEDVKIVFQALYNTVNEIGAKASALQGHDVTKYLVDVWLHVVRCMKVEAEWQRSQHLPTFEEYMESGMVSLGQGATVMSALFLIGEKLPEGVVELEEYDEMFRLMGTCGRLLNDIRGIEREESDGKMTNGVSLLVHASGGSMSVDEAKTEVMKRIDASRRKLLSLVVGEQEGPIPRPCKQLFWKMCKILHLFYYQTDGFSSPKEMVSAVDAVIKEPLQLRSL
What is the function of this protein?
Involved in phytocassane phytoalexins biosynthesis.  Catalyzes the conversion of ent-copalyl diphosphate to the phytoalexin precursor ent-cassa-12,15-diene.
What are the official names of this protein?
Ent-cassa-12,15-diene synthase, Diterpene cyclase 1, OsDTC1, Ent-kaurene synthase-like 7, OsKSL7.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RL2_LACDB
Sequence: MAIKVYKPTSNGRRNMTSSDFAEITKSKPEKTLLASKSKTAGRNSYGHITVRHRGGGHKQQYRIIDFKRTKDNVKAKIVAIEYDPNRSANIALLHYTDGTKAYILAPKGLTVGSWVESGVDADIKVGNALPLKNIPTGTEVHNIELKPGKGGQIARSAGTSAQVLGVDGKYTQVRLQSGEVREILSECRATIGAVGNEQHSLINIGKAGRSRWMGKRPQSRGSVMNPNDHPHGGGEGKAPVGRPQPMTPWGKKSRGIKTRDSKKASEKLIIRHRKGRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS14_SYNPW
Sequence: MAKKSMIARDAKRKKMVERFAAKRSALMAAFNAAEDPMERLEIHRKIQGLPRNSAPTRMRNRCWATGKPRGVYRDFGLCRNQLRERAHKGELPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: EFUF_HORCR
Sequence: MATSVEADTKSQVNLKVANDGGESASETGVVDVYDDPLIHNSIRKKLDLKLLPLLSAMYLFNAIDRSNLGNAKTDGLEKDLHMKGNEYSITLVLFYVTFCLLDVPANMLLKKFSGKIMLPTLMMGWGSMTLIQCAVHNWGGLIACRLLMGAFEAGFMAGVVYYLTTFYRRNELALRISIFYGAATIAGAFSGLLAYGVFQINHPSIPGWKFLMIIEGSATILLASFAYWHLPSSVLSCKWFTEEEKHVAEQRMLHDGSIQTDEKFALKTALANLLDWKIALYAVIGISYGVASASVGNFLPQMVQRLGFGTVKTNLYTVAPYCVGCVILLAQCTSSDHFRERSTHLAGAMLLTFVGFILLITLDTEAQPGPTYFACFLLAAGAFTPSCIFHSWHNNNTPSENGRAAVTGFMVGASNSGGIISSLAFASKTAPKYIPALIVTATFQGVGIVLVLGFGAWFRWDNRRRDRVQGVRIRTGDVATVSVDDASWRWTA
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of enfumafungin, a glycosylated fernene-type triterpenoid with potent antifungal activity, mediated by its interaction with beta-1,3-glucan synthase and the fungal cell wall (PubMed:30051576).  Might facilitate the transport of glucose units to the subcellular site of enfumafungin biosynthesis (Probable).
What are the official names of this protein?
MFS-type transporter efuF, Enfumafungin biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENO_NOVAD
Sequence: MTAIIDIHAREILDSRGNPTVEVDVLLEDGSFGRAAVPSGASTGAHEAVELRDGDKARYLGKGVTKAVTAVNSDIAECILGLDAEDQRDIDLAMIELDGTENKSRLGANAILGTSLAVAKAAADARGLPLYSYVGGVSAHVLPVPMMNIINGGEHADNPIDFQEFMIMPVGAPSLAEAVRWGAEVFHTLKKGLHEKGLATAVGDEGGFAPNLASTRDALDFVMASIEKAGFKPGEDMMLALDCAATEFFKNGKYEISGEGLSLSPDAMADYLAALCDAYPIISIEDGMGEDDFEGWAALTAKVGKRVQLVGDDLFVTNPKRLEMGIGKGLANSLLVKVNQIGSLTETLEAVSIAQRNGYTAVMSHRSGETEDATIADLAVATNCGQIKTGSLARSDRLAKYNQLIRIEEELGVSARYAGKTAFGRLGA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y713_LATSS
Sequence: MELAQNARMNSLFEFYGALLTAKQHSYLSLYYGDDFSLGEIAEEYQVSRQAVYDNIRRTEKILEGYEAKLHLFQNYEQQNASADALQKYIQAQYPNDQQLAKLLADLLNLTEQ
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein LCA_0713.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: H2A1_TETPY
Sequence: MSTTGKGGKAKGKTASSKQVSRSARAGLQFPVGRISRFLKNGRYSERIGTGAPVYLAAVLEYLAAEVLELAGNAAKDNKKTRIVPRHILLAIRNDEELNKLMANTTIADGGVLPNINPMLLPSKTKKTSEAEH
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.1, Histone H2A.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to both the large, transcriptionally active, somatic macronucleus (MAC) and the small, transcriptionally inert, germ line micronucleus (MIC).
Protein: GSTM5_MOUSE
Sequence: MSSKSMVLGYWDIRGLAHAIRMLLEFTDTSYEEKRYICGEAPDYDRSQWLDVKFKLDLDFPNLPYLMDGKNKITQSNAILRYIARKHNMCGDTEEEKIRVDIMENQIMDFRMQLVRLCYNSNHENLKPQYLEQLPAQLKQFSLFLGKFTWFAGEKLTFVDFLTYDVLDQNRIFEPKCLDEFPNLKAFMCRFEALEKIAAFLQSDRFFKMPINNKMAKWGNKCLC
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase Mu 5, Fibrous sheath component 2, Fsc2, GST class-mu 5.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_METPB
Sequence: MATASFDSAPGASRALPAIEKAPEVTALSTLPGRKASLVGLTREGLKQALIGIGVPERETRMRVSQIWHWLYVRGAREFSEMTNVGKGLKAQLAEHFTLDRPEVVTEQVSRDGTRKWLLRMAPTGAHDHNRGAEIECVYIPGDDRGTLCVSSQVGCTLTCSFCHTGTQRLVRNLSTAEIVSQLVVARDALGDFTGQMPGKDGGEVGRLVTNIVFMGMGEPLYNLDAVIDAIAVMSDQEGLALSRRRITVSTSGVVPQIERLGLEANAMLAISLHAVRDELRDELVPLNRKYPIAQLLEACRNYPGLSNARRITFEYVMLKGVNDSDADARALVRLLKGIPAKINLIPFNPWPGSKYECSDWERIERFSEFVFNAGYASPVRTPRGRDILAACGQLKSETEKLRARARMMLEEGMGAEAVYADQVD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_SYNR3
Sequence: MAGKRFWILLSAAGLLLLDQLSKQWWLQNLPPGVSQSWIPGLLNLRLVWNDGAAFSLFRSGSQWLGWISLLVSVGLLIWIGRRGRQWSRWQAAAAAFLLAGSVGNGIDRWRYGAVIDGLELVPFSFPVFNLADVAINLAVLCLLIEAIRQR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACCA_ECO27
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLSVPTICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTC_SHISS
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRHPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 6PGL_SODGM
Sequence: MKQIVYVASPESQQIHVWQMDNQGALTLLQVVDTPGQGQPMVIHPARTHLYIGVRPSFGVVSYRIDEKGLLTEAGMAPLPGSPTQLTTDLQGETLYSVSYSGSCLSVSPIDEQGIVGAPTQTLEGLTHCHSANVDTTNQVLWVPCLQEDRIRLYTIGEAGHLTPRTPEALDSVAGAGPRHMVFHHGGGYAYAINELSGTVNVIAIDAAGAGPRIVQTLDIMPAGFSDTRWAADIYITPDGRWLYCCDRTASVISRFAVSEDGGVLRLLGHQATESQPRGFNIDSQGRFLVAAGQKSHHIAVYAIDAQSGALDPLARYAVGQGPMWVSVLAR
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: FAR5_DELRA
Sequence: PGQDFMRF
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
FMRFamide-like neuropeptide PGQDFMRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LACC_STAES
Sequence: MILTLTLNPSVDISYPLDQFNLDTVNRVSQTSKTAGGKGLNVTRVLSEFGEDVIASGFLGGALGQYIEEQIETTRIKQAFFKIKGETRNCIAILHEGQQTEILEKGPTIELKESEEFKSHLLKLFKETDVAVMSGSLPKGLNTDYYTDIVRLAKEQGILTILDSSGQSLEEVLISNEKPTVIKPNIDELSQLLNYKVTNDIKELKAAVSQPIFNDIEWIIVSLGSEGAFAKHNQKFYKVNIPNIKVVNPVGSGDSTVAGIASGLIHQQTDEELLKKANAFGMLNAMEQQTGHINTDKFDEIFKQIEVIEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.