PharMolix/UniProtQA huggingface dataset:
Protein: RSMA_PARMW
Sequence: MAFQGHQARKRFGQHWLKDQTVLDRIVAAADLQPSDRVLEVGPGRGALTERLLSSPAAAVQAVELDRDLVDGLRERFAGDPRFSLRQGDVLELPLQLEDGVAASKVVANIPYNITGPLLDRLVGRLDRPVEPPYQRLVLLVQKQVAERIRARPGHSSFSALSVRMQLLARCTTVCPVPPRCFQPPPKVQSEVIQIDPLPADKRLPSDIARRVESLLRQAFLARRKMLRNTLASLAPEPQLQALAAAAGFQLHQRPQELAPQVWVALARGLNQGIDAASADGHDHGDGSGQGESSPGGARDQI
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUP_CORGL
Sequence: MNAKQTQIMGGGGRDEDNAEDSAQASGQVQINTEGVDSLLDEIDGLLENNAEEFVRSYVQKGGE
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: GREA_STAAB
Sequence: MENQKQYPMTQEGFEKLERELEELKTVKRPEVVEKIKVARSFGDLSENSEYDAAKDEQGFIEQDIQRIEHMLRNALIIEDTGDNNVVKIGKTVTFVELPGDEEESYQIVGSAESDAFNGKISNESPMAKALIGKGLDDEVRVPLPNGGEMNVKIVNIQ
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: LSPA_AGRVS
Sequence: MTRSAALFCRPVPAILFILSLLILDQAIKYAVEVSLPMHELVPVVPMLGLFRTHNLGVAFSMLSHLDAWVIVVMRLAIVAFVAWLWRQTSRDHQFAHLGYCLIIAGAFGNIIDRFTYGYVVDYILFHTETWSFAVFNLADSLITIGAGFILLEELLVLRRSKG
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH60_PSEPF
Sequence: MAAKEVKFGDSARKKMLVGVNVLADAVKATLGPKGRNVILEKSFGAPTITKDGVSVAKEIELEDRFENMGAQLVKDVASRANDDAGDGTTTATVLAQSIVNEGLKAVAAGMNPMDLKRGIDKATIAVVAELKKLSAPCTDTKAIAQVGTISANSDNSIGDIIAEAMEKVGKEGVITVEEGSGLENELSVVEGMQFDRGYLSPYFVNKPDTMVAELEGALILLVDKKISNIREMLPVLEAVAKAGRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAVLTGGTVISEEIGLSLESTTLEHLGSAKRVTLSKENTIIVDGAGNDGDIQARIAQIRAQVAETSSDYDREKLQERLAKLSGGVAVIKVGAGSEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALIRALNAIINLKGDNADQDVGIAVLRRAVEAPLRQIAANSGDEPSVVVNEVKNGKGNFGYNAATGEYGDMIEMGILDPTKVTRSALQAASSIGGLILTTEAAVADAPKKDGAAGGGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF3_ASHGO
Sequence: MSDSAQSIKVLGELFEKLSVATAENREATATEIASFLNGNIIEHDVPEEFFKNLTKAVKDKKTAAAALETIAHIANENNLSPSVEPYIVDLVPEVCVKTGDKDKDVQSIASETLLAIVKAIDPVAIKVILPHLTKSLVTTNKWQEKVSVLAAISALVDAAKTQVALRMPELIPVLSEAMWDTKKEVKHAATATMTKATETVDNKDIERFIPELIQCIADPSQVSETVHLLGATTFVAEVTPATLSIMVPLLNRGLAERETSIKRKAAVIIDNMCKLVEDPQVVAPFLEKLLPGLKNNFATIADPEAREVTLRGLKTLRRVGNVSDDDTLPEVSHAGDIVTTRGVLDELTKDTPIAPRFAPVVNYIAAIAADLIDERIIDQQAWFTHVTPYMTVFFHEKQSKEIIDDFRKRAVDNIPVGPNFDDEEDEGEDLCNCEFSLAYGAKILLNKTQLRLKRARRYGLCGPNGAGKSTLMRAIANGQVDGFPTQDECRTVYVEHDIDGTQADTSVLDFVFQGDVGTREVITEKLREFGFSDEMIAMPIMSLSGGWKMKLALARAVLKNADILLLDEPTNHLDTVNVAWLVNYLNTCGITSIIVSHDSGFLDNVCQYIIHYEGLKLRKYKGNLSEFVKKCPTAKSYYELGASDLEFKFPEPGFLEGVKTKQKAIVKVSNMSFQYPGTSKPQIADINFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTTGEVYTHENCRIAYIKQHAFAHIENHLDKTPSEYIQWRFQTGEDRETMDRANRQINESDAESMNKIFKIDGTPRRIAGIHSRRKFKNTYEYECSFLLGENIGMKSERWVPMMSVDNAWLPRGELIESHSKMVAEVDMKEALASGQFRPLTRKEIEEHCAMLGLEAELVSHSRIRGLSGGQKVKLVLAACTWQRPHLIVLDEPTNYLDRDSLGALSKALKAFEGGVIIITHSAEFTKDLTEEVWAVKDGIMTPSGHNWVSGQGSGPRLEKKEDEGDKFDAMGNKIATGNKKKKLSSAELRKKKKERMKKKKELGDAYVSSDDEF
What is the function of this protein?
Ribosome-dependent ATPase that functions in cytoplasmic translation elongation (By similarity).  Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis (By similarity).  Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied (By similarity).
What are the official names of this protein?
Elongation factor 3, EF-3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_SERP5
Sequence: MTCAQVIRQFYQATIMTATAQQLQFIKDSIKTIPDYPKPGILFRDVTSLLENPLAYAASIELLVERFREAGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRATLSESYELEYGTDKLEIHTDAISAGDKVLVVDDLLATGGTIEATAKLIRRLGGEVTDAAFIINLPDLGGEARLNTLGIECYSLVNFSGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_BRUA4
Sequence: MTAGVSPDDYSIEPELLLRAYATGIFPMAEEADDPEVFWVRPERRGVIPLDGFHMPKSLQKTIRQGIFDIKLDNDFDGVIEGCASGTGERARTWINGPIREAYKNLFEIGHCHTVEAWHDGQLVGGLYGVTLGRAFFGESMFTRKRDASKVCLAYLVQHLVKQGFVLLDTQFTTPHLERFGAVEVPRKKYEKLLENALDGIVRF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_AERPE
Sequence: MSQREAGQVDLEAWQPRTRVGRLVKEGKIKSIDEIFRRNLPILETEIVDYLLPGLDHEVIDVSIVQKMTDAGRITRFRAVVVVGNKDGYVGLGKGKARQFRFAIEKAIRNAKLNIIPVRRGCGSWECTCGEAHSVPFTVRGKSGSVEVILKPAPKGTGLVAGDVAKVVLRLAGISDVWTFTKGETRTSYNFARATYLALRNTYRFVTPADWAEARLRL
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: KAIB_RIPO1
Sequence: MVNFKKTYVLKLYVAGNTPNSVRALKTLKNILEDEFKGVYALKVIDVLKNPQLAEEDKILATPTLSKILPPPVRKIIGDLSDREKVLIGLDLLYEEIRERESEL
What is the function of this protein?
A metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, KaiA and CikA.  KaiA and CikA compete for binding to KaiB(fs), and KaiB(fs) and SasA compete for binding to KaiC, thus the clock oscillator and output signal pathway are tightly coupled.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: NAGZ_SHESR
Sequence: MSYLMLDLLSLDVSEAEAEMLRHPQVGGLILFSRNFSSREQLISLVQQIRQIRPEILIAVDHEGGRVQRFREGFTLIPAMGDILPAAKGDMLLAKRWACELGFLMAIELLACDIDLSFAPVLDLNGISQVIGKRSFSAKPDEVIALAQSFIEGMAEAGMGAVGKHFPGHGSVAADSHIAQAIDEREAEAIFNQDILPFKELIAKGKLSGIMPAHVIYPKVDPNPAGFSSYWLQQILRQELGFDGVIFSDDLGMKGASFAGDYLGRAQAALDAGCDMILVCNDNPGVMSLLNGFVWPDDAPQHPTSLLKPNVAQTAIALENSARWENAKQLAEQIQLAQQAKV
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_XANCB
Sequence: MNDSAHIDYARYDHIRPLLWTGDALELLDQRKLPFVVEHVRCDSSDAVAEAIHSLAVRGAPAIGIAAGWGVVLAAREIAADSGSEALQKLEPALLRLNAARPTAVNLAWALMRMRRVLAAAGPDWRDVLAREAQAIADEDLAANRHMGALGAGLIAPGSGVLTHCNTGSLATAGFGTALGVIRAGMAQQRISKVFAGETRPWLQGARLTVWELQQDGIDATLIADSAASHLMKSGLVQWVIVGADRICANGDTANKIGSYQLAIAARHHGVKFMVVAPSSTVDMATADGDQIEIEQRDPGELFGVGGVRTVADGIHAWNPVFDVTPGHLIDAIVTERGVIAQPDLARMQAAFGN
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: IP2T_SOLTU
Sequence: MAVHKEVSFVAYLLIVLGMFLYVDALGCTKECGNLGFGICPRSEGSPTNPICINCCSGYKGCNYYSAFGDLICQGESDPKNPKACPLNCDTNIAYSRCPRSEGKSLIYPTGCTTCCTGYKGCYYFGTNGKFVCEGESDEPKPYMSTA
What is the function of this protein?
Inhibitor of trypsin and chymotrypsin.
What are the official names of this protein?
Proteinase inhibitor type-2 T, Proteinase inhibitor type II T.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I20 (potato type II proteinase inhibitor) family.
Protein: OPGC_ECOHS
Sequence: MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1464_NITEU
Sequence: MAISDWPEAERPREKLIEKGAAALSDAELLAIFLRTGITGVSAVELARKLLTHFGSLTKLCAASLHEFSELPGMGPAKFAQLQAVMEMAKRALAEELKNGDIMDSPQSVRNYLCLSLKGKPYEVFVGIFLDARHRTIVTEELFNGTLTQASVYPREVVKRALYHNAAAMIFAHNHPSGIAEPSTADEILTQSLKQALALVDVKVLDHFVIGSSEVVSFAERGLI
What are the official names of this protein?
UPF0758 protein NE1464.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RL16_COPPD
Sequence: MLMPKRVKYRKNHLPHIKGKETRGLKLAFGDYGIQAVGRGYVDSRMIESCRVIMAKNIGKTGKYWIRIFPDVAWTKKPLEVRMGGGKGDPEKWIFPVKPGRIMFELTGVDEDTAKHIARLIGFRLPFEVRLISRV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: GLYCO_MOKV
Sequence: MNIPCFVVILSLATTHSLGEFPLYTIPEKIEKWTPIDMIHLSCPNNLLSEEEGCNAESSFTYFELKSGYLAHQKVPGFTCTGVVNEAETYTNFVGYVTTTFKRKHFRPTVAACRDAYNWKVSGDPRYEESLHTPYPDSSWLRTVTTTKESLLIISPSIVEMDIYGRTLHSPMFPSGVCSNVYPSVPSCETNHDYTLWLPEDPSLSLVCDIFTSSNGKKAMNGSRICGFKDERGFYRSLKGACKLTLCGRPGIRLFDGTWVSFTKPDVHVWCTPNQLINIHNDRLDEIEHLIVEDIIKKREECLDTLETILMSQSVSFRRLSHFRKLVPGYGKAYTILNGSLMETNVYYKRVDKWADILPSKGCLKVGQQCMEPVKGVLFNGIIKGPDGQILIPEMQSEQLKQHMDLLKAAVFPLRHPLISREAVFKKDGDADDFVDLHMPDVHKSVSDVDLGLPHWGFWMLIGATIVAFVVLVCLLRVCCKRVRRRRSGRATQEIPLSFPSAPVPRAKVVSSWESYKGLPGT
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane.  There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: LRGA_BACCQ
Sequence: MSTKKVYSFLSQAFIFSAIMLISNIIATHLPIPMPSSVIGLVILFSLLCLKVIKLEQVESLGTALTGIIGFLFVPSGISVINSLGVMGQYFVQILTVIVVATVILLAVTGLFAQFILGKDKKETEDTKELKVVNKGRKHGKVA
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UVRB_YERPY
Sequence: MSKSFKLHSVFKPAGDQPEAIRKLEEGLENGLAHQTLLGVTGSGKTFTVANVIADLNRPTMILAPNKTLAAQLYGEMKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTRGMIIDQRSILRRLSELQYSRNDQVFQRGTFRVRGEVIDIFPAESDEWALRVELFDEEVERLSIFDPLTGQLQHEVPRFTVYPKTHYVTPRERILQAMEEIKVELAERRQVLLANNKLLEEQRLSQRTQFDLEMMNELGYCSGIENYSRYLSGRGPGEAPPTLFDYLPADGLLIVDESHVTIPQIGGMYKGDRSRKETLVEYGFRLPSALDNRPMRFEEFEALAPQTIYVSATPGKYELEKSGGDIIEQVVRPTGLLDPLIEVRPVATQVDDLLSEIRIRAAINERVLVTTLTKRMAEDLTDYLSEHGAKVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYGDRITASMEKAIGETERRRAKQQAYNEERGIIPQGLNKKIGDILQLGQPSMRGKGKGRGSHKMADTTQYQSLSPKALDQKIRELEAKMYTYAQNLEFEQAAELRDQVHQLRQQFIAIS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NL1A1_RAT
Sequence: MEESQSKQESNTRVAQHGSQQDVDPTFQTKRALEKERSKPRPRPLPRVQLQSLPGWSSTSNDVPLSQLIREMDHESRRCIHRSKKKLDRSEHISQGTIPEIYEKRKETISHTQSMEQKYLFQNFTKLLLLQKCCPGGSEKLVRESWHPCVPEEGGHMIEIQDLFDPNLDTEKKPQLVIIEGAAGIGKSTLARQVKRAWDEGQLYRDRFQHVFFFSCRELAQCKQLSLAELIAQGQEVPTAPTRQILSRPEKLLFILDGIDEPAWVLEDQNPELCVHWSQAQPVHTLLGSLLGKSILPEASLMLTARTTALQKLVPSLGQPHRVEVLGFSEFERKDYFYKYFAKERNTIIDFNLIGSIPVLLTLCEVPWVCWLLCTCLEKQMQQGEVLSLTSQTTTALCLKYLSLTIPGQHLSTQLRTLCSLAAEGICQRRTLFSKSDLCKQGLAEDAIATFLKIGVLQRQPSSLSYSFAHLCLQEFFAAMSYILEDSEEAHGDMGNDRTVETLVERYGRQNLFEAPTVRFLLGLLNTREMREMENIFACKFPWETKLKLLQSIIGEPFCQPCHLGLFHCLYENQEEELLTETMLCFPLTASGPNHMEATVFQTNVKRLVIQTDMELMVVTFCITFSHVRSLRLKGKGQQEYKLTAPAMVLYRWTPISEASWKVLFSNLKCTRNLEELDLSGNPLSYSAVRSLCTALRQPGCRLKTLWLVDCGLTSRCCSFLASMLSAHSRLAELDLRLNDLGDNGVRQLCEGLRNPACNLSILRLDQASLSEQVITELRALETKNPKLFISSTWMSHMTMPTENTDGEESLTSSKQQQQQSGDKHMEPLGTDDDFWGPSGPVSTEVVDRERNLYRVRLPMAGSYHCPSTGLHFVVTRAVTIEIGFCAWSQFLHETPLQHSHMVAGPLFDIKAEHGAVTAVCLPHFVSLQEGKVDSSLFHVAHFQDHGMVLETPARVEPHFAVLENPSFSPMGVLLRMIPAVGHFIPITSITLIYYRLYLEDITFHLYLVPNDCTIRKAIDEEELKFQFVRINKPPPVDALYVGSRYIVSSSKEVEILPKELELCYRSPRESQLFSEIYVGNIGSGINLQLTDKKYMNLIWEALLKPGDLRPALPRMASAPKDAPALLHFVDQHREQLVARVTSVDPLLDKLHGLVLSEEDYETVRAEATNQDKMRKLFRGSRSWSWDCKDHFYQALKETHPHLIMDLLEKSGGVSVRL
What is the function of this protein?
Constitutes the active part of the Nlrp1a inflammasome (PubMed:33731929).  In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, N-terminus), preventing activation of the Nlrp1a inflammasome.  In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing this form, which polymerizes to form the Nlrp1a inflammasome complex: the Nlrp1a inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 1a allele 1.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [NACHT, LRR and PYD domains-containing protein 1a, C-terminus]: Inflammasome.
Protein: RNPH_BRUSI
Sequence: MRPSKRAADEMRAISFERGVSKHAEGSCLVKFGDTHVLCTASLEEKVPGWMRNTGKGWVTAEYGMLPRSTGERMRREAAAGKQGGRTQEIQRLIGRSLRAVVDMQALGEMQITVDCDVIQADGGTRTAAITGGWVALHECLRWMEARQMVRVEKVLKDHVAAISCGIYEGVPVLDLDYAEDSVAETDSNFVMTGKGGIVEIQGTAEGVPFSEEEFGALMKLARSGIDRLVSLQKMAVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ARGR_CLOK5
Sequence: MKVTRHAKILEIINSNNIETQEELAEKLKNSGMNVTQATVSRDIKELKLIKVLSDNGRYKYATISRTESFLSNKLVNIFSQTVVSVENIDNFVVIKTISGSASAAAEAIDSLGFIGIAGTIAGDNTIFVMARDREKAHGITQKMKKMISQ
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_TRIEI
Sequence: MDSKYNPVSIEQKWQKNWAEQNQDQTPINNNQPKFYALSMFPYPSGNLHMGHVRNYTITDVIARLKRMQGYRVLHPMGWDAFGLPAENAAIDRGIPPAKWTLENIAQMKEQLRRLGFSIDWDKEVATCTPEYYRWTQWIFLQFFQAGLAYQKESAVNWDPIDQTVLANEQVDGEGRSWRSGAKVERKMLRQWFFKITDYAEQLLNDLDKLPGWPERVKLMQANWIGKSVGAYLEFPIVGMDQKIGVFTTRPDTVYGVSYVVLAPEHPLTAKVTTPEQQITVETFIKEVAAESELERTAEDKPKRGVPTGGKAINPFNNQEVPIWIADYVLYEYGTGAVMGVPAHDVRDFQFAKQYNLPIKTVIVPDDSNDDHKLTEAYTDVGVMVNSGPFNGEKSTVAKKAIIELAEDEGYGKGRVQYRLRDWLISRQRYWGAPIPIIHCPKCGAVPVPDEDLPVKLPESVEFSGRGPSPLAKLEDWVNVSCPSCGTPAKRETDTMDTFIDSSWYYLRYPDATNEEQVFDSKIVNDWLPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLCDFDEPFQNLLTQGMVQGVTYKNPVTGKYIPFADVNPQEPKDPKTGDKLEVFFEKMSKSKYNGVDPMDVMATYGADTARMFILFKAPPEKDLEWDDADVQGQFRFLNRVWSMVMEFLANHSFSELKAKHHGITQADLKDLGWSRYLITEITKNISAFKLRNVVKVYPVEDVLVAIEAKFNYSETQQETKDDLQKVLTWIKSRFGGELTKAEKDVRRAVHNAIKEVTEDLDGDYQFNTAVSEMMKLSNALGDASCKDSPIYAEALETLLLLLAPFAPHITEELWQIAGNFGSVHTHAWPKFDPEALVVDEITLVIQIKGKTRGTIQVPAQADKETLEKLARESDIAQRHLAGKEIKKVIVVPRKLVNFVVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF4_IPOPU
Sequence: MSWRSEHIWIELLPGSRKISNFCWAFILFLGSLGFLLVGISSYLGRNLISFFPSQQIIFFPQGIVMSFYGIAGLFISSYLWCTISWNVGSGYDLFDRREGIVCIFRWGFPGRNRRIFLRFLIKDIRSVRIEVKEGIYARRVLYMDIRGQRAIPLTRTDENLTPGEIEKKAAELAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ATB13_ARATH
Sequence: MSCNNGMSFFPSNFMIQTSYEDDHPHQSPSLAPLLPSCSLPQDLHGFASFLGKRSPMEGCCDLETGNNMNGEEDYSDDGSQMGEKKRRLNMEQVKTLEKNFELGNKLEPERKMQLARALGLQPRQIAIWFQNRRARWKTKQLEKDYDTLKRQFDTLKAENDLLQTHNQKLQAEIMGLKNREQTESINLNKETEGSCSNRSDNSSDNLRLDISTAPPSNDSTLTGGHPPPPQTVGRHFFPPSPATATTTTTTMQFFQNSSSGQSMVKEENSISNMFCAMDDHSGFWPWLDQQQYN
What is the function of this protein?
Probable transcription factor that may act in the sucrose-signaling pathway.
What are the official names of this protein?
Homeobox-leucine zipper protein ATHB-13, HD-ZIP protein ATHB-13, Homeodomain transcription factor ATHB-13.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LGT_ENTFA
Sequence: MMLAQVNSIAFRLFGIPVYWYAIIIVSGIALAVWLSSREAVRVGLKEDDVFDFMLWGLPAAIVGARLYYVAFQWQDYVDNPIEIFFTRNGGLAIYGGLIGGGLALFFFTRHRFISTWTFLDIAAPSVILAQAIGRWGNFMNHEAYGPATTRQFLENLHLPTFIIDNMNINGTYHQPTFLYESVWNVLGFIVLVLLRKKPHFLKEGEVFLGYIIWYSFGRFFIEGLRMDSLYAFSNIRVSQLLSLVMFVAAIVIVIVRRRNPNLKFYNREKQKKKITTS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.