PharMolix/UniProtQA huggingface dataset:
Protein: RK32_CRUWA
Sequence: MAVPKKRTSISKKRIRKNIWKRKGYWTSLKAFSLGKSLSTGNSKSFFVQQNK
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NK_METJA
Sequence: MGGKMEKITCVGHTALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLSCVGYDFKNSGYERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAAKHYKELNPPNFNTEIVHIATGDPEFNLKCAKKAYGNNLVSFDPGQDLPQYSKEMLLEIIEHTNFLFMNKHEFERASNLLNFEIDDYLERVDALIVTKGSKGSVIYTKDKKIEIPCIKAGKVIDPTGAGDSYRAGFLSAYVKGYDLEKCGLIGAATASFVVEAKGCQTNLPTWDKVVERLEKHRI
What is the function of this protein?
Catalyzes the phosphorylation of a wide range of nucleosides to yield nucleoside monophosphates.  Shows the highest activity for inosine, guanosine and cytidine, but very poor kinase activity with adenosine, thymidine, uridine and xanthosine.  ATP is the best phosphate donor, but can also use ITP and GTP.  Shows extremely low activity with fructose-6-phosphate.
What are the official names of this protein?
Nucleoside kinase, NK, ATP-dependent nucleoside monophosphokinase, Cytidine kinase, Guanosine-inosine kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: MINY4_MOUSE
Sequence: MDSLYVEEVAASLVREFLSRKGLNKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYKENKAKEKPLRTNLELITRYFLDNVGNTDNSESQEVPIPAIPVPKKNNKLPLRHSETTLVNIYDLSDEDTGRRTSWSEAGKARHDSLDGDILGNFVSSKKPSHKSKAAHVDLGDSLPLVPAWEKVDQLHSSEPGIDVKKTMERTRPKSGLIVRGMMAGPVASSPQDSFRKRSLRRSSALSRKLQTPEEIQQQSEPFVHTPAYLGPQEVPDSSSDSVSRSPLGQLNELSIEKPNVTSSSQGLSQRDRPRLRSVSEDSPLGYSHTEGNSRMAQDQLERAFKRQGVQPPSLRKNQLVSDRTDDKPDALQLEDVEDELIKEDIVLFPPPSMLKLQTVSKPIDLSLAKEIKTLLFGSTFCCFSEEWKLQNFSFNDIASLKYGIVQNKGGPCGVLAAVQGCVLQKLLFEGDNRTNSNLRLQPSDAQRTRCLALAIADILWRAGGKEQAVVALASGTPHFSPTGKYKADGVLETLTLYSLTSSEDLVTFIQQSVHQFEAGPYGCILLTLSAILSRSLELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNITLLRGIEARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLCDWRSERLFDLYYYDGLANQQEEIRLTVDTTKTAPADSCSDLVPPLELCIRTKWKGASVNWNGSDPIL
What is the function of this protein?
Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.
What are the official names of this protein?
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4, Probable deubiquitinating enzyme MINDY-4.
What is the protein family that this protein belongs to?
Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
Protein: RSMA_ECOBW
Sequence: MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_STRP8
Sequence: MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSNPNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: OGFR_RAT
Sequence: MDDPDCDSTWEEESEEDGEDGQADDTTDEDTGDDDGDAEEARPSLFQSRMTGYRNWRAMQDMQRYRHNYPDLTDQDCNGDMCNLSFYKNEICFQPNGALIEDILQNWKDNYDLLEENHSYIQWLFPLREPGVNWHAKPLTLKEVEAFKSSKEVRERLVRAYELMLGFYGFHLEDRGTGAVCRAQNFQPRFHNLNSHSHNNLRITRILKSLGELGLEHYQAPLVRFFLEETLVQHKLPSVRQSALDYFLFAVRCRHQRRELVYFAWEHFKPRREFVWGPRDKLRRFKPQTIPQPLTGPGQADKDEGSRDPSQEAGTQGRTCGSGRDLSGDSGTAEDPSLLNTKPSDGGTLDGNQRDEAKSLSPKESKKRKLEGNRQEQVPGEADPQGVSEVEKIALNLEECALSPISQEPREAEPPCPVARVANEVRKRRKVEEGAEGDGVVSNTQMQASALPPTPSECPEAQKDGNGPEDSNSQVGAEDSKSQVGPEDPNSQVGLEDPNSQVGPEDPNSQVGPEDPNSQVGPEDPNSQVGPEDPNSQVVGPEQAASKSPVEDPDSDTMGTSVDESEELARIEASAEPPKP
What is the function of this protein?
Receptor for opioid growth factor (OGF), also known as Met-enkephalin.  Seems to be involved in growth regulation.
What are the official names of this protein?
Opioid growth factor receptor, OGFr, Zeta-type opioid receptor.
What is the protein family that this protein belongs to?
Belongs to the opioid growth factor receptor family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Note=The OGF/OGFR complex is probably translocated to the nucleus. Colocalized with OGF in the perinuclear region.
Protein: RS16_PROM5
Sequence: MIKLRLKRFGKKKEASFRIVACNSTSRRDGRPLQELGFYNPRTKETRLDTEALRIRLTQGAQPTDVVRTLLEKGGLLEKKVRPSIAIGKANLEKEKIAKAKSKESESANKEAES
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MAZE2_MYCBO
Sequence: MKTAISLPDETFDRVSRRASELGMSRSEFFTKAAQRYLHELDAQLLTGQIDRALESIHGTDEAEALAVANAYRVLETMDDEW
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Labile antitoxin that binds to cognate MazF2 toxin and counteracts its endoribonuclease activity.
What are the official names of this protein?
Antitoxin MazE2.
Protein: IXTPA_SULSY
Sequence: MKILLATTNEGKVRELRQLLKDLDIEILSLKDMDKKLEVEEDKETFLENAIKKATSYAKFYKLPVIAEDSGLEVDALNGLPGIYSARFFDIEFGKEVLKEIPENLSKDEKNNLKLLRLLENQTNRKARYKTALVFYNFDYGIWTEGVCEGQIAYKPEGNQGFGYDPIFIPEGYNKTMAQLTPEEKNKISHRGKAVSKLVEILKKVL
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: NU4LM_MUNCR
Sequence: MSLVYMNIMTAFMVSLAGLLMYRSHLMSSLLCLEGMMLSLFVLATLTILNSHFTLASMMPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BLH7_ARATH
Sequence: MATYYKTGSSEIYSRPEFVPGNAMNYTNSFTETFPRDSTNNVSPSKEIQVLSSLGGVSQMVEIQDSGSWRDQEDNDRNRFPVMRRLGLSSQIETSRGNNNNEYATQVVSGFTRTIHNSKYLKAAQELLDETVNVKKALKQFQPEGDKINEVKEKNLQTNTAEIPQAERQELQSKLSKLLSILDEVDRNYKQYYHQMQIVVSSFDVIAGCGAAKPYTALALQTISRHFRCLRDAISGQILVIRKSLGGEQDGSDGRGVGISRLRNVDQQVRQQRALQRLGVMQPHTWRPQRGLPDSSVLVLRAWLFEHFLHPYPKDSDKIMLARQTGLSRGQVSNWFINARVRLWKPMVEEMYKEEFTDALQENDPNQSSENTPEITEIQELQTESSSNNGHVPGVASSSMRQNTVAHGGDRFMMVTDMTRNGNGGMSLTLGIQNSDARGDVPMSGGIDNYKNTISGTDLQYLNSRNHQHQIGSSQLLHDFVA
What are the official names of this protein?
BEL1-like homeodomain protein 7, BEL1-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the TALE/BELL homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IR02_HCMVA
Sequence: TSLVDGVGGSTSPGIASFAATLLHRYPINPSPRHDVSAYLCSLKNPSPRPPIPSTPHAITNHGHDKCMQTSHLLCLLLCVATGSEEGEGKEKKKEQNNRLAEGIIRATELVLLFL
What are the official names of this protein?
Uncharacterized protein IRL2, TRL2.
Protein: RL29_STAAS
Sequence: MKAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIRTVRKTIARLKTVAREREIEQSKANQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CLPP_PORGI
Sequence: MNEFKKYATRHIGLNAQALDDYTRIQSSYISPTIIEERQLNVAQMDVFSRLMMDRIIFLGTQIDDYTANVIQAQLLYLDSADPGKDISIYLNSPGGSVYAGYGIYDTMQYIGCDVATICTGMAASMASVLLVAGTKGKRFALPHSRVMIHQPLGGMQGQASDLEIAAREILRVKKELYTIISSHSGKPVEQVEKDSDRDYWMTAPEALEYGMIDKILEKNRK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_EHRRW
Sequence: MRVLLSNDDGFHANGIKALKEIVIKSGIASEIWVVAPLNNCSGSGRSVGLNVKVQVSKVSDTEFIVDSTPSTSVFLALRKIMNYKPDLILSGINHGVNIGNDVWYSGTVAAAAEGAAINIPSIAISQEYDNKSGEINWVNPQRFLKQIIEMLMNVSFWNKSTVMNVNFPLMPAKGIKFTDQGKYVPCNEIEKNESSDDSNVSYTITRITPNKKNRAQCDGSIKAIDEGYITITPLKFDMTDFDVLTSLNSLK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_STRPS
Sequence: MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKVFVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASHNPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKYEGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGSTHPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLAQNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMDYNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAIKAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVNYYVDTITDVVRAEIGID
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TRMB_BACLD
Sequence: MRMRHKPWADDYLAENSHIVISEPSQYKGKWHSVFGNDNPIHIEVGTGKGQFISGMALQNPDVNYIGIELFKSVIVTAVDKVKQTEAPNVKLLNINANMLSDVFADGEVDRVYLNFSDPWPKKRHEKRRLTNHAFLKKYEQVLGGKGAIHFKTDNRGLFEYSLTSFSEYGLVLTFVSLDLHQSDFEGNVMTEYEEKFAAKGQPIYRVEAEWRT
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RS8_METJA
Sequence: MSLMDPLANALNHISNCERVGKKVVYIKPASKLIGRVLKVMQDNGYIGEFEFIEDGRAGIFKVELIGKINKCGAIKPRFPVKKFGYEKFEKRYLPARDFGILIVSTTQGVMSHEEAKKRGLGGRLLAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS13_BORPA
Sequence: MARIAGINIPPQQHAEIGLTAIFGIGRTRARKICEAAGVPVTKKVKDLTDAELERIREHIGVFAVEGDLRREVQLSIKRLIDLGTYRGMRHKRGLPVRGQRTRTNARTRKGPRRAAASLKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL272_ARATH
Sequence: MVKFLKQNKAVILLQGRYAGKKAVIIKSFDDGTSDRRYGHCLVAGLKKYPSKVIRKDSAKKTAKKSRVKCFIKLVNYQHLMPTRYTLDVDLKEVATLDALKSKDKKVTALKEAKAKLEERFKTGKNRWFFTKLRF
What are the official names of this protein?
60S ribosomal protein L27-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL27 family.
Protein: RENR_HUMAN
Sequence: MAVFVVLLALVAGVLGNEFSILKSPGSVVFRNGNWPIPGERIPDVAALSMGFSVKEDLSWPGLAVGNLFHRPRATVMVMVKGVNKLALPPGSVISYPLENAVPFSLDSVANSIHSLFSEETPVVLQLAPSEERVYMVGKANSVFEDLSVTLRQLRNRLFQENSVLSSLPLNSLSRNNEVDLLFLSELQVLHDISSLLSRHKHLAKDHSPDLYSLELAGLDEIGKRYGEDSEQFRDASKILVDALQKFADDMYSLYGGNAVVELVTVKSFDTSLIRKTRTILEAKQAKNPASPYNLAYKYNFEYSVVFNMVLWIMIALALAVIITSYNIWNMDPGYDSIIYRMTNQKIRMD
What is the function of this protein?
Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the lysosomal proton-transporting V-type ATPase (V-ATPase) and the acidification of the endo-lysosomal system (PubMed:12045255, PubMed:29127204, PubMed:30374053, PubMed:32276428).  May mediate renin-dependent cellular responses by activating ERK1 and ERK2 (PubMed:12045255).  By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, may also play a role in the renin-angiotensin system (RAS) (PubMed:12045255).  Through its function in V-type ATPase (v-ATPase) assembly and acidification of the lysosome it regulates protein degradation and may control different signaling pathways important for proper brain development, synapse morphology and synaptic transmission (By similarity).
What are the official names of this protein?
Renin receptor, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H(+)-transporting lysosomal-interacting protein 2, ER-localized type I transmembrane adapter, Embryonic liver differentiation factor 10, N14F, Renin/prorenin receptor, Vacuolar ATP synthase membrane sector-associated protein M8-9, ATP6M8-9, V-ATPase M8.9 subunit.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Lysosome membrane; Single- pass type I membrane protein. Cytoplasmic vesicle, autophagosome membrane; Single-pass type I membrane protein. Cell projection, dendritic spine membrane; Single-pass type I membrane protein. Cell projection, axon. Endosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein.
Protein: HE65_NPVAC
Sequence: MVYICIDTGSHAKGYAVESSDTDYHIYTKCDRETFEKFIDNKELLKNRHAKDESGNDVKYVDLYTGLIGILTGKSPELSMFSKREDFKDKYGIENLQLYEFVTKLMTVSMVKIIYTLMRYKILNNAKGLLQLMFNYVYVEYYLDYKRAPKSTKILNMLFNVGDEIKITMDKNNQLVVNDLNVLDLNKNNGGYKIDETLTLFVKNVKLLKLYVKLMQRGEYQQEWTEYFQQWKQQLQDRLHHVPEPPERTDIRHNIVMYALNERGPVMPEDENKIVYQIYPSVSHLDQGKKGTLADKEIIVQEKLDGCNFRIICNQNKITYGSRNTYRPDGNFMNYYRIRKDLETCMRSLQARFNDGFIVYGELMGWKDDAKTTPINVINYVDQKESLKYYAYEIQLYGGEFVPFVEAQELLTNVGFNTIPCHKYLYNDFVERLNFKSLMFPQSPLEGFIIRCGNLIYKLKSDYKDLNKLKIEKGPFEWLTCDYIKSNCDAIDKSDMMKILIFCYNMCKVKNYNEKLLFNKVFNLFRQQFNLNHNDYKNLYKQYVNMCKCTEYK
What is the function of this protein?
May participate in the recruitment of G-actin to the host nucleus.
What are the official names of this protein?
Protein Early 65 kDa.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PROA_AROAE
Sequence: MDIHDYMQTLGRQARAASRVLATASTADKNAALVAMAAAIREQTGELLAANARDLDEARAAGLEAALIDRLTLTAKGIEAMAEGLEQVAGLPDPIGEITDVKRRPSGIQVGKMRVPLGVIGIIYEARPNVTADAAALCLKSGNAAILRGGKEALHCNQAIAQCVRTGLAAAGLPETSVQVVETTDRAAVGHLITMPEFVDVIVPRGGKGLIERISKEARVPVIKHLDGNCHVYIDRDADVAKVVPIVENAKTQRYGTCNTAESLLVAREVAPRLLPEIGRMLATKGVEMRGCEQSLAILRAAGIAADKLRAASEQDWSEEYLAPVIAVKVVADLDEAIAHINTYSSGHTEAIVTENYTSAMRFLREVDSSSVMVNASTRFADGFEYGLGAEIGISTDKIHARGPVGLDGLTSQKWIVFGNGEIRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_OCHKO
Sequence: MTNIRKTHPLMKIINHSLIDLPAPSNISAWWNFGSLLGLCLGIQIITGLFLAMHYTSDTLTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGIYYGSYTYSETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPTGIISDADKIPFHPYYTIKDAFGFLLLISLLLTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSIAILAAMPLLHTSKQRSMMFRPISQTLFWILVADLLTLTWIGGQPVEHPFIIIGQLASFFYFFLILILMPTSSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS3_ECO8A
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: FRDD_SHEPC
Sequence: MINYSPKRSDEPIWWGLFGAGGVWFAMITPVTVLLMGILLPLHGFGVVDIGYDKVYAFVSHPIGGAFTVLSLSLPMWHAMHRVHHGLHDLQIHLGTVGKYACYLAAALVTVLATVWVIQLS
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROK_NITWN
Sequence: MTSETVSPSSFGASPETAVVAALAGRSLALVGMMGAGKSTIGRRLAARLRMRFVDADAEIELAAGMPIPEIFETHGEPHFRDGEARVIARLLNGGPIVLATGGGAVLREETRARLSERAVSIWLKADAEVILRRVRRRADRPLLQTADPAATIKRLIAEREPIYRQADITVASRDVPYEWIVDECIGLLHRRLCRGEMTRNAMKDPDEGFDTTQ
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_FLAPJ
Sequence: MQHNVLILDFGSQYTQLIARRVRELNIFCEIFPFDKIPTDLSIYKAVILGGSPFSVRSEDALHPDLSEIRGKLPLLAVCYGAQYLAHFSGGEVAASNTREYGRANLTYIKENETFFENVNLNSQVWMSHSDSIKKLPTNGIKLASTQDVENAAYKIEGETTYAIQYHPEVFHSTDGKQMLENFLVKIAQVPQNFTPNAFVSDMVAELKEKLQDDKVVLGLSGGVDSTVAAVLLHQAIGKNLYCIFVNNGLLRKNEFQSVLDQYKGMGLNVKGVDAGDRFLSELAGISDPETKRKTIGRVFIEVFDDESKIIENVKWLAQGTIYPDVIESVSVKGPSATIKSHHNVGGLPDYMKLQIVEPLRMLFKDEVRRVGATLGIDAELLGRHPFPGPGLSIRILGDITPEKVQILQDVDAVFINGLKEHGLYDKVWQAGAILLPVNSVGVMGDERTYEKVVALRAVESTDGMTADWVHLPYEFLMKISNDIINKVKGVNRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: INSI2_CHICK
Sequence: MAENDAKPTLPKKSGPYISSVTSHGMNLVIRGIVLFFIGVFLALVLNLLQIQRNVTLFPPDVITSIFSSAWWVPPCCGTASAVIGLLYPCMDRHLGEPHKFKREWSSVMRCVAVFVGINHASAKVDFANNIQLSLTLAALSIGLWWTFDRSRSGFGLGVGIAFLATLVSQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHED
What is the function of this protein?
Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR.  Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs).  Binds oxysterol, including 22-hydroxycholesterol, 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol, regulating interaction with SCAP and retention of the SCAP-SREBP complex in the endoplasmic reticulum.  In presence of oxysterol, interacts with SCAP, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing SCAP from escorting SREBPs to the Golgi.  Sterol deprivation reduces oxysterol-binding, disrupting the interaction between INSIG2 and SCAP, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBPs.  Also regulates cholesterol synthesis by regulating degradation of HMGCR.
What are the official names of this protein?
Insulin-induced gene 2 protein, INSIG-2.
What is the protein family that this protein belongs to?
Belongs to the INSIG family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AN32B_SHEEP
Sequence: MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSDNRICGGLDMLAEKLPNLTHLNLSGNKLKDIGTLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQLTYLDGYDREDREAPDSDAEVDGVDEEEDDEEGENEDKEEDEDGEEEEFDDEEDDDEDEDVEGEEDEDKVSGEEEEFGHDGEADEDDEDEDEDEDEDEEEEESGKGEGRKRETDDEGEDD
What is the function of this protein?
Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor.  Required for the progression from the G1 to the S phase.  Anti-apoptotic protein which functions as a caspase-3 inhibitor.  Has no phosphatase 2A (PP2A) inhibitor activity.  Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome (By similarity).
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32 family member B, Acidic protein rich in leucines, Leucine-rich acidic nuclear protein, LAN.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates in the nuclei at the S phase.