PharMolix/UniProtQA huggingface dataset:
Protein: LSPA_GLOC7
Sequence: MMKKNRWFWLVAIIGLGLDQLTKYITVQSFETIGDTFGLWPGVFHLTYVINTGAAFSFFKGGAVWLRWLSLAVSLGLIFLGWYAPRMRIVEQLGYGFILAGALGNGIDRFLFGYVVDFLDFRLINFPVFNLADTFINIGIFFLLLASFPPKSSSQKNTSQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NADK_HELMI
Sequence: MPTVGVVLNDDKPQALEVARRMADWLSQREVPMGIPLTRVAELVHSPSPELRDRLRQLDLIVVLGGDGTLLNTARLAAPHGIPVVGVNLGRLGFLTEVEVSDLFPALERIIAGDYRIEERMMLEARLIRDGLEQPSYFALNDVVVTKGDHPRMIRVEAAVGDEVVWTYSADGLIVSSPTGSTAYSLSAGGPIVSPELHALLLTPISPHALDARPLVIPQDQAVRLTVISSHSHAVVTVDGQPGQPMVCGDSVLVRKASVACRLIRLGERTFFRILREKMQQGR
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBL2_HUMAN
Sequence: MELSQMSELMGLSVLLGLLALMATAAVARGWLRAGEERSGRPACQKANGFPPDKSSGSKKQKQYQRIRKEKPQQHNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTKDFLQREHRSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHAAVSPCGRFVASCGFTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKKQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALASGSSIHLYNTRRGEKEECFERVHGECIANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQLTQAQETLKSLGALKK
What are the official names of this protein?
Transducin beta-like protein 2, WS beta-transducin repeats protein, WS-betaTRP, Williams-Beuren syndrome chromosomal region 13 protein.
Protein: UBE12_WHEAT
Sequence: MLPRKREIVAGEVEDLQKKTRAGEGEATREEGDAAMAGRGNEIDEDLHSRQLAVYGRETMKPLFGSNVLVSGLQGLGAEIAKNLVLAGVKSVTLHDDGNVELWDLSSNFFLSENDVGQNRAQACVQKLQELNNAVLVSALTGDLTKEHLSKFQAVVFTDISLDKAIEFDDYCHSHQPPIAFIKSEVRGLFGSVFCDFGPEFTVLDVDGEEPHTGIVASISNDNPALVSCVDDERLEFQDGDLVVFSEVHGMTELNDGKPRKVKNARPYSFFLEEDTSSFGAYVRGGIVTQVKPPKVIKFKPLKEAMSEPGEFLMSDFSKFERPPLLHLAFQALDKFRTELSRFPVAGSTDDVQRVIEYAISINDTLGDRKLEEIDKKLLHHFASGSRAVLNPMAAMFGGIVGQEVVKACSGKFHPLYQFFYFDSVESLPVDPLEPGDLKPKNSRYDAQISVFGSTLQNKLEEAKIFMVGSGALGCEFLKNLALMGISCSQNGNLTVTDDDVIEKSNLSRQFLFRDWNIGQPKSTVAATAAMVINPKLHVEALQNRASPETENVFNDAFWENLDAVVNALDNVTARMYIDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPTEVNAFLSNPTTYISAARTAGDAQARDQLERVIECLDRDKCETFQDSITWARLKFEDYFSNRVKQLTFTFPEDSMTSSGAPFWSAPKRFPRPVEFSSSDPSQLSFILAAAILRAETFGIPISEWAKTPNKLAAEAVDKVIVPDFQPKQGVKIVTDEKATSLSSASVDDAAVIEELIAKLEEVSKTLPSGFHMNPIQFEKDDDTNFHMDVIAGFANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKALAGGHKVEDYRNTFANLAIPLFSIAEPVPPKTIKHQELSWTVWDRWTVTGNITLRELLEWLKEKGLNAYSISCGTSLLYNSMFPRHKERLDRKVVDVAREVAKMEVPSYRRHLDVVVACEDDDDNDVDIPLVSVYFR
What is the function of this protein?
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP.
What are the official names of this protein?
Ubiquitin-activating enzyme E1 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
Protein: CRCB_ACIC5
Sequence: MKYLWVALGGALGALARYTVGVWIYERLGTRFPYGTFAINVTGCFLIGLALTVLDAHMDLSPAWRLAIPTGFIGAYTTFSTFEYETLRAAQHGQMGTAVLYFGSSLALGILAVWLGMVVGNRIVA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DTD_BURCJ
Sequence: MIALIQRVTRADVRVGGRTTGEIGAGLLALVCAERGDTEAAADKLLAKLLGYRVFSDAAGKMNLPVSNIDGEGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGARLFDYFVAAARARHPVVETGEFGADMQVSLVNDGPVTFWLQVRP
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_THET2
Sequence: MLEEALAAIQNARDLEELKALKARYLGKKGLLTQEMKGLSALPLEERRKRGQELNAIKAALEAALEAREKALEEAALKEALERERVDVSLPGASLFSGGLHPITLMERELVEIFRALGYQAVEGPEVESEFFNFDALNIPEHHPARDMWDTFWLAGEGFRLEGPLGEEVEGRLLLRTHTSPMQVRYMVAHTPPFRIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGITMAHLKGAIYELAQALFGPDSKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYRERLGLPSAYRGVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKFLEQFKGVL
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR5_AUSRA
Sequence: TDRNFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-5, FMRFa-5.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCKG_THEAC
Sequence: MLAIDESELNQHAMKWIEGIKKFTEAEDVVVCDGTPEEFKQISNELIKSGEFIKLNENRYPNSFLYRSDRTDVARSEERTFIAAPDASMAGSLNNHMTLQQVSEVWNKFFRGAYRGKTMFVIPYALGPLNSRFTDYGIEITDSRYVVLNLHYITRMGKQVIGSMPEKFVKGVHATGTLDPGNKFIIHIPWDKPEGVDADILSVNTNYGGNALLSKKCHALRIASVRARKEGWLAEHMLLLEVEDPHGRKVYITGAFPSASGKTNLAMINPPKQYAEAGWKTRLLSDDIAWMKMKDGMLYATNPENGFFAVVPGTNYRTNKNAMITLSRNTIFTNTGMTKTGEPWWEGLDPLQEELYDWKGVLRKPDGEPIAHPNSRFTSPLSNYPFLSDRSEDPEGVPVSAILFGGRRASLVPLVYEAFNWNHGVFMGATMGVEKTAASEGKVGELRRDPMAMRPFCGYNISDYFRHWIEMGRKLSRRPKIFYVNWFRRRQDGSFIWPGFSENFRVIEWILYRLDHNDNAIETPIGYIPENINTDGLNLTKQDMEELFRIDRDGWREEMKSIGDYFSQIGNIPEDLLIEFEMEKRRIS
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIS1_NEMVE
Sequence: MVLTPRQKEELNKAIADYLHQCGFEDTLNAFKQDANMPGELDKKYTGLLEKKWTSVIRLQKKVMDLETRLSEAEKEVHHGGGPKKTRSPEDWIPRPPERYTLTGHRSPITKVLFHPVYSVMVTSSEDATVKVWDYETGDFERTLKGHTDAVQDLAFDHTGKFLASSSADMTIKLWDFQGFECIRTLHGHDHNVSSISFLPSGDHLVSASRDKTIKMWEIATGYCVKTFQGHGEWVRRVRPNADGSLIASCSNDQTIRVWVVASRECKCDLRDHDHVIEDLNWAPESATPVINEAAGVEGGKKAMSPGPFLVSASRDKSIKIWDVSAGVCLVTLVGHDNWVRAVMFHPGGKFIVSCSDDKTLRIWDYKNKRCAKTLVAHEHFVTTLDFHKSAPFVATGSVDLTLKVWECR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes.
What are the official names of this protein?
Lissencephaly-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the plus end of microtubules and to the centrosome.
Protein: KINH_NEUCR
Sequence: MSSSANSIKVVARFRPQNRVEIESGGQPIVTFQGPDTCTVDSKEAQGSFTFDRVFDMSCKQSDIFDFSIKPTVDDILNGYNGTVFAYGQTGAGKSYTMMGTSIDDPDGRGVIPRIVEQIFTSILSSAANIEYTVRVSYMEIYMERIRDLLAPQNDNLPVHEEKNRGVYVKGLLEIYVSSVQEVYEVMRRGGNARAVAATNMNQESSRSHSIFVITITQKNVETGSAKSGQLFLVDLAGSEKVGKTGASGQTLEEAKKINKSLSALGMVINALTDGKSSHVPYRDSKLTRILQESLGGNSRTTLIINCSPSSYNDAETLSTLRFGMRAKSIKNKAKVNAELSPAELKQMLAKAKTQITSFENYIVNLESEVQVWRGGETVPKEKWVPPLELAITPSKSASTTARPSTPSRLLPESRAETPAISDRAGTPSLPLDKDEREEFLRRENELQDQIAEKESIAAAAERQLRETKEELIALKDHDSKLGKENERLISESNEFKMQLERLAFENKEAQITIDGLKDANSELTAELDEVKQQMLDMKMSAKETSAVLDEKEKKKAEKMAKMMAGFDLSGDVFSDNERAVADAIAQLDALFEISSAGDAIPPEDIKALREKLVETQGFVRQAELSSFSAASSDAEARKRAELEARLEALQQEHEELLSRNLTEADKEEVKALLAKSLSDKSAVQVELVEQLKADIALKNSETEHLKALVDDLQRRVKAGGAGVAMANGKTVQQQLAEFDVMKKSLMRDLQNRCERVVELEISLDETREQYNNVLRSSNNRAQQKKMAFLERNLEQLTQVQRQLVEQNSALKKEVAIAERKLMARNERIQSLESLLQESQEKMAQANHKFEVQLAAVKDRLEAAKAGSTRGLGTDAGLGGFSIGSRIAKPLRGGGDAVAGATATNPTIATLQQNPPENKRSSWFFQKS
What is the function of this protein?
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.  Its motor activity is directed toward the microtubule's plus end.
What are the official names of this protein?
Kinesin heavy chain.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y06_BPT7
Sequence: MMKHYVMPIHTSNGATVCTPDGFAMKQRIERLKRELRINRKINKIGSGYDRTHDGLKKGYMPNGTLYAANRRIVRTWRENNLERRKDKRGRRGIDERKRLKPRNSPHLNRH
What are the official names of this protein?
Protein 0.6B.
Protein: MDH_HAEDU
Sequence: MKVTVLGAAGGIGQTLSLLLKLRLPAGADLALYDISPVTPGIAVDISHIPTSVNAIGYAGEDPSVALKDPSVALKDTNLVIITAGIARKPGMTRADLFNINAGIVKDLVEKVAEVCPMACIGIVTNPVNTLVPIAAEVLRKAGVYDKSKLFGVTTLDVVRAKTFVSELKHKNVETVTVPVVGGHSGTTILPLLSQALAEGRLLDFSQTEIESLTQRIKNAGTEVVEAKAGGGSATLSMAESGARFALAVFKALLGEDCVRYAYVQSKEGSGYPEFFAHPVRFGLKGIEEILPIAPLNEYEQTQFEELKPILEADIELGKKFVNP
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: DPOZ_YEAST
Sequence: MSRESNDTIQSDTVRSSSKSDYFRIQLNNQDYYMSKPTFLDPSHGESLPLNQFSQVPNIRVFGALPTGHQVLCHVHGILPYMFIKYDGQITDTSTLRHQRCAQVHKTLEVKIRASFKRKKDDKHDLAGDKLGNLNFVADVSVVKGIPFYGYHVGWNLFYKISLLNPSCLSRISELIRDGKIFGKKFEIYESHIPYLLQWTADFNLFGCSWINVDRCYFRSPVLNSILDIDKLTINDDLQLLLDRFCDFKCNVLSRRDFPRVGNGLIEIDILPQFIKNREKLQHRDIHHDFLEKLGDISDIPVKPYVSSARDMINELTMQREELSLKEYKEPPETKRHVSGHQWQSSGEFEAFYKKAQHKTSTFDGQIPNFENFIDKNQKFSAINTPYEALPQLWPRLPQIEINNNSMQDKKNDDQVNASFTEYEICGVDNENEGVKGSNIKSRSYSWLPESIASPKDSTILLDHQTKYHNTINFSMDCAMTQNMASKRKLRSSVSANKTSLLSRKRKKVMAAGLRYGKRAFVYGEPPFGYQDILNKLEDEGFPKIDYKDPFFSNPVDLENKPYAYAGKRFEISSTHVSTRIPVQFGGETVSVYNKPTFDMFSSWKYALKPPTYDAVQKWYNKVPSMGNKKTESQISMHTPHSKFLYKFASDVSGKQKRKKSSVHDSLTHLTLEIHANTRSDKIPDPAIDEVSMIIWCLEEETFPLDLDIAYEGIMIVHKASEDSTFPTKIQHCINEIPVMFYESEFEMFEALTDLVLLLDPDILSGFEIHNFSWGYIIERCQKIHQFDIVRELARVKCQIKTKLSDTWGYAHSSGIMITGRHMINIWRALRSDVNLTQYTIESAAFNILHKRLPHFSFESLTNMWNAKKSTTELKTVLNYWLSRAQINIQLLRKQDYIARNIEQARLIGIDFHSVYYRGSQFKVESFLIRICKSESFILLSPGKKDVRKQKALECVPLVMEPESAFYKSPLIVLDFQSLYPSIMIGYNYCYSTMIGRVREINLTENNLGVSKFSLPRNILALLKNDVTIAPNGVVYAKTSVRKSTLSKMLTDILDVRVMIKKTMNEIGDDNTTLKRLLNNKQLALKLLANVTYGYTSASFSGRMPCSDLADSIVQTGRETLEKAIDIIEKDETWNAKVVYGDTDSLFVYLPGKTAIEAFSIGHAMAERVTQNNPKPIFLKFEKVYHPSILISKKRYVGFSYESPSQTLPIFDAKGIETVRRDGIPAQQKIIEKCIRLLFQTKDLSKIKKYLQNEFFKIQIGKVSAQDFCFAKEVKLGAYKSEKTAPAGAVVVKRRINEDHRAEPQYKERIPYLVVKGKQGQLLRERCVSPEEFLEGENLELDSEYYINKILIPPLDRLFNLIGINVGNWAQEIVKSKRASTTTTKVENITRVGTSATCCNCGEELTKICSLQLCDDCLEKRSTTTLSFLIKKLKRQKEYQTLKTVCRTCSYRYTSDAGIENDHIASKCNSYDCPVFYSRVKAERYLRDNQSVQREEALISLNDW
What is the function of this protein?
Nonessential DNA polymerase.  Required for DNA damage induced mutagenesis.  Involved in DNA repair, mitochondrial DNA repair and translesion synthesis.  Translesion synthesis in S. cerevisiae may use a specialized DNA polymerase that is not required for other DNA replicative processes.  Has a role in the bypass of abasic (AP) sites.  Highly inefficient in incorporating nucleotides opposite the AP site, but efficiently extends from nucleotides, particularly an A, inserted opposite the lesion.
What are the official names of this protein?
DNA polymerase zeta catalytic subunit, Protein reversionless 3.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.
Protein: MBTL_MYCTO
Sequence: MTSSPSTVSTTLLSILRDDLNIDLTRVTPDARLVDDVGLDSVAFAVGMVAIEERLGVALSEEELLTCDTVGELEAAIAAKYRDE
What is the function of this protein?
Acyl carrier protein involved in the formation of acyl-S-ACP intermediates within the mycobactin biosynthesis process.  The aliphatic chains carried by ACP are subsequently transferred on to the mycobactin core by MbtK (By similarity).
What are the official names of this protein?
Acyl carrier protein MbtL, ACP, Mycobactin synthase protein L.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_SALSV
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDNFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLSVDANAHCDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECAMEIGQMNFKVMSILDAGETTKYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGSYDDRIWTRSIVGWPGVSHLEGDDFGPVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSRKKLRHIFLVGGCDGARGERNYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFFTPDLLAILNEKFGLRSVTTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_VIBVU
Sequence: MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDADFEPKSLEQQSKQAATESKKDKEQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TMP_BPT5
Sequence: MTDKLIRELLIDVKQKGATRTAKSIENVSDALENAAAASELTNEQLGKMPRTLYSIERAADRAAKSLTKMQASRGMAGITKSIDGIGDKLDYLAIQLIEVTDKLEIGFDGVSRSVKAMGNDVAAATEKVQDRLYDTNRALGGTSKGFNDTAGAAGRASRALGNTSGSARGATRDFAAMAKIGGRLPIMYAALASNVFVLQTAFESLKVGDQLNRLEQFGTIVGTMTGTPVQTLALSLQNATNGAISFEEAMRQASSASAYGFDSEQLEQFGLVARRAAAVLGVDMTDALNRVIKGVSKQEIELLDELGVTIRLNDAYENYVKQLNATSTGIKYTVDSLTTYQKQQAYANEVIAESTRRFGYLDDALKATSWEQFAANANSALRSLQQSAATYLNPVMDTLNTFLYQTKSSQMRVSAMARSASAKTTPAENVTALIENAVGAREDLDTYLKESEERVKKAQELKQQLDDLKAKQAATAPIANALTAGGIGGDESNKLVVQLTNELARQNKEIEERTKTEKVLRQAVQDTGEALLRNGKLAEQLGAKMKYADTAVPGDKGVFEVDPNNLKAVSEIQKNFDFLKKSSSDTANNIRMAASSITNAKKASSDLNSVVKAVEDTSKVTGQSADTLVKNLNLGFSSLDQMKAAQKGLSEYVTAMDKSEQNALEVAKRKDEVYNQTKDKAKAEAAAREVLLRQQQEQLTAAKALLAINPNDPEALKQVAKIETEILNTKAQGFENAKKTKDYTDKILGVDREIALLNDRTMTSTQYRLAQLRLELQLEQEKTELYSKQADGQAKVEQSRRAQAQISREIWEAEKQGTASHVSALMDALEVSQTQRNVTGQSQILTERLSILQQQLELSKGNTEEELKYRNEIYKTSAALEQLKKQRESQMQQQVGSSVGATYTPTTGLIGEDKDFADMQNRMASYDQAISKLSELNSEATAVAQSMGNLTNAMIQFSQGSLDTTSMIASGMQTVASMIQYSTSQQVSAIDQAIAAEQKRDGKSEASKAKLKKLEAEKLKIQQDAAKKQIIIQTAVAVMQAATAVPYPFSIPLMVAAGLAGALALAQASSASGMSSIADSGADTTQYLTLGERQKNVDVSMQASSGELSYLRGDKGIGNANSFVPRAEGGMMYPGVSYQMGEHGTEVVTPMVPMKATPNDQLSDGSKTTSGRPIILNISTMDAASFRDFASNNSTAFRDAVELALNENGTTLKSLGNS
What is the function of this protein?
Fills the tail tube with its long coiled-coil domain and has pore-forming properties for host membrane penetration.  Probable exolysin involved in host peptidoglycan digestion necessary for viral DNA entry into the host cell.  Also functions as a tape measure protein that serves as a base for tail tube protein polymerization and acts as a template for tail length determination.
What are the official names of this protein?
Tape measure protein pb2, TMP-pb2, Pore-forming protein pb2, Tail protein pb2.
What are the subcellular locations of this protein?
Virion. Note=Probably fills the tail tube with its coiled-coil domain and has its C-terminus within the tail tip.
Protein: RS17E_METJA
Sequence: MGRIRQTLIKRTAMELIKKYRDLFTTDFETNKRVLEEVAQISTKRLRNRIAGYITHKMRQLQ
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: ALGF_PSEPK
Sequence: MTTKTSIAKALTLAAGLSLASMQAFAGADAALYGPSAPKGSTFVRLYNATSAPAAASVGNTQIKQVGAQASSDFSFLPGGDYTAQVGGKSVPVKLASDKYYTLVNSNSGSPKLIEEPPFKNKQKALVRVQNLSDQQLTLKTADGKTEVVKPVAANGRGEREINPVKVNLALYQGDKKVGDVKPVALERGEAAVLYVTGSGNALSPVWVTRPVASN
What is the function of this protein?
Together with AlgI and AlgJ, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues.  Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity).
What are the official names of this protein?
Alginate biosynthesis protein AlgF.
What is the protein family that this protein belongs to?
Belongs to the AlgF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HADL_PSEPU
Sequence: MKNIQGIVFDLYGTLYDVHSVVQACEEVYPGQGDAISRLWRQKQLEYTWLRSLMGRYVNFEKATEDALRFTCTHLGLSLDDETHQRLSDAYLHLTPYADTADAVRRLKAAGLPLGIISNGSHCSIEQVVTNSEMNWAFDQLISVEDVQVFKPDSRVYSLAEKRMGFPKENILFVSSNAWDASAASNFGFPVCWINRQNGAFDELDAKPTHVVRNLAEMSNWLVNSLD
What is the function of this protein?
Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids (PubMed:1588303).  Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 (PubMed:1588303).  Active with 2-halogenated carboxylic acids and converts only the S-isomer (or L-isomer) of 2-chloropropionic acid with inversion of configuration to produce R-lactate (or D-isomer) (PubMed:1588303).
What are the official names of this protein?
(S)-2-haloacid dehalogenase, 2-haloalkanoic acid dehalogenase, Halocarboxylic acid halidohydrolase, L-2-haloacid dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
Protein: LCL2_LEPMJ
Sequence: MARPYMIFAVLTAWFFGCNAQFGFFDQMFGGGGGGGQQQQQPQNVRSDSVWYQQQYEAAQCSHYLCPGTLSCVHFPHHCPCAWEGVEEKIELGEGIAICASKGGWAEGEFAKKVELARKGML
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: URED_MYCS2
Sequence: MKLAERTAADLRFARAGAHTVLTRRRHRWPFVIGRVFADPQDPGLGTLTLQNAAGTVIPGDVIRQRIEVVDGGRAAVNGQGATLISGVPGGDASAEETELYVDAHSWLRFDPAPRILTAHARHRQRTEVCVAHRGCAVVVDAVVLHPDLDAATFGSIESTVTVRSPGGALLAMDAQVLDAPPVTGRFTAFGTVYFVGAGFTGGHHEGPTDPPGVYTAVTELPNGAGCAVRIAAADGGTLRTYLRLLSAETAFQRASTRTFTDGMPFRRSQV
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1530_YERE8
Sequence: MSAYSRPVLLLLCGLLLFTISIAVLNTLVPLWLSHQQLPTWQVGMVSSSYFSGNLVGTLIAGRIIQQLGFNRSYHYSCILFALATCGLMLSVDFWSWLGWRFFAGVACALIWVIVESALLRSGTVTNRGQLLAAYMMVYYLGTVTGQLLLGVVSTQLLSVIPWVSALVITAMLPLLFAHFSHQDSGDVPHIAVWPMLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHQGMSDASVGWWMALLVSSGIIGQWPIGKMADRYGRLLVLRIQVFVVILGSIAILGNYALAPALFILGCAGFTLYPVAMAWACEKVSADKLVAMNQALLMSYTIGSLTGPTMTSLLMQRYSDNLLFIMIAGVALVYLMMLLRKPDQQKTPFAAV
What are the official names of this protein?
Uncharacterized MFS-type transporter YE1530.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIP41_YEAST
Sequence: MSKRNTPPLRSSGINTIQINAAREMHAQTVRARRMPMPTSGITTPSVQPTAAPATPPRHICNNPNNPQCLHCGSVIIPSPRATLPLEDNPSISINDWTISSRKKPILNSQELDIWENEKLKGLTLPEMIFGNNYIRIENSKQHWSIEFNALDALKEVQLQDSGIRVAYSNDWINSKKRQNSTNGAQRFTNDVNDDSLNIIHKYDWTYTTRYKGTESSPESKFRLDNDQKLPLDKLAVHDKILFYDDMILFEDELADNGISILNVKIRVMNERLLLLSRFFLRVDDVLVRVYDTRIYVEFDENVVIRESKEFEGKYQDVLAKHRLSQSHDPKAALRDSNWVAQNTPMIKRQCEIIQF
What is the function of this protein?
Involved in negative regulation of the TOR signaling pathway in response to type of available nitrogen source.  Indirectly activates the PP2A phosphatase SIT4 via interaction with its suppressor TAP42.  This interaction is enhanced under nitrogen limitation conditions.  Also has a role in regulation of NPR1 in response to nitrogen limitation.
What are the official names of this protein?
Type 2A phosphatase activator TIP41, PP2A phosphatase activator TIP41, TAP42-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the TIP41 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ISPD_PSEPG
Sequence: MINTLPAFWAVIPAAGVGARMAADRPKQYLELAGQTLLEHSLDCFLGHPALAGVVVSIADDDPYWPGLRYASDPRIQRAAGGRERADSVLNALLVLHAQGASDSDWVLVHDAARPNLARSDLDKLLSELADDPVGGLLAVPARDTLKRADGNGRVSATVDRSTIWQAYTPQMFRLGALHRALAECLVSDVVVTDEASAIEWSGQAPRLVEGRSDNIKVTRPEDLEWLRQRWAGRR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: UL88_HHV6Z
Sequence: MNVPMADEWFDCAIRLDSETIAVHEIFNSDLSKLLNLHSKTVYMSDLCAFISGCVNRNVGKLTIYWHVYGDIIYALTGILHCVKITIECGERIADGRYRLYEIPKLFLMRGQSTPLELKWKHAVGIATTNKPLLTHVLTDVLETSPFTLPDTLLSVQELSIFRERLSYIYYVLGLDVDIVARTEREIFQKCAELARLQQVFLIQGNIMENFVLVQACLFQLGADGLWEEMSGSVRPRPELMSSAFIQHRVMVNNCYCLAVIFNAIYKHKVSLPTVERSHEIVHRVVQEYYKSYVNAPLSVLVCATKVLTLFTEEYNFQSALVFVSQFFQVDVEASRADVIRLFLACLKGD
What are the official names of this protein?
Protein U59.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U59/UL88 family.