PharMolix/UniProtQA huggingface dataset:
Protein: VPS9_YEAST
Sequence: MTDDEKREILKEFDPFSQLEQANGNPDKDVKFKKDDPNRAAAEETNRDISAQDKGDEEPFYDFQIFIKQLQTPGADPLVKYTKSFLRNFLAQRLLWTVSEEIKLISDFKTFIYDKFTLYEPFRSLDNSKMRNAKEGMEKLIMGKLYSRCFSPSLYEILQKPLDDEHMKDLTNDDTLLEKIRHYRFISPIMLDIPDTMPNARLNKFVHLASKELGKINRFKSPRDKMVCVLNASKVIFGLLKHTKLEQNGADSFIPVLIYCILKGQVRYLVSNVNYIERFRSPDFIRGEEEYYLSSLQAALNFIMNLTERSLTIEDHEDFEEAYQRNFKQLAEEKEEEEKKKQLEIPDELQPNGTLLKPLDEVTNIVISKFNELFSPIGEPTQEEALKSEQSNKEEDVSSLIKKIEENERKDTLNTLQNMFPDMDPSLIEDVCIAKKSRIGPCVDALLSLSE
What is the function of this protein?
Required for vacuolar protein sorting; may be required for the consumption of transport vesicles containing vacuolar protein precursors.  May bind a Rab GTPase such as VPS21.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 9, Vacuolar protein-targeting protein 9.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK1_BLAGE
Sequence: GSSGLIPMGRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, BlaGe-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIE_RUBGI
Sequence: MNEPTPLSRSFGYQSVDEREREQRIRRVFSAVAARYDLMNDLMSFGIHRLWKRRFVRMAAPQAGQHIVDLAGGTGDVAALMAAADRRVTVVDPSAEMMAVGQARGHAHVDWQVGSAEQLPLADASVDTLTISFGIRNATRIDVALREIHRVLKPGGRFLCLEFSTPAWWLRPFYNLFSFTVIPRLGAWIANSPEAYTYLVESIRRFPDQRGFAAMISAAGFESVRWHDLSFGIACVHVGTRAAAATPAGTA
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: DRE2C_ARATH
Sequence: MPSEIVDRKRKSRGTRDVAEILRQWREYNEQIEAESCIDGGGPKSIRKPPPKGSRKGCMKGKGGPENGICDYRGVRQRRWGKWVAEIREPDGGARLWLGTFSSSYEAALAYDEAAKAIYGQSARLNLPEITNRSSSTAATATVSGSVTAFSDESEVCAREDTNASSGFGQVKLEDCSDEYVLLDSSQCIKEELKGKEEVREEHNLAVGFGIGQDSKRETLDAWLMGNGNEQEPLEFGVDETFDINELLGILNDNNVSGQETMQYQVDRHPNFSYQTQFPNSNLLGSLNPMEIAQPGVDYGCPYVQPSDMENYGIDLDHRRFNDLDIQDLDFGGDKDVHGST
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates high salinity- and abscisic acid-inducible transcription.
What are the official names of this protein?
Dehydration-responsive element-binding protein 2C, Protein DREB2C.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FAP1_ARATH
Sequence: MVSFRFPFSFSQPPRATTSFSGFSISAVAVSVTVGAAAAGAAIAASRNPSHPILEWAFSSHRSSLSPWGSITLADESVVEPKTGFSFPASIGDSRRLLGVGLRKKSLLGLKNIDVYAFGVYADCDDVKKLVGDKYANLPASEIRGNKSFMDDLMEADIKMTIRLQIVYGKLNIRSVRNAFQESVGNRLKKFGGSDNDELLQSFTSLFKDEYKIPRNSTIDLTKDPGHVLSVAIEGNHVGSVKSHLLCRSILDLYIGEEPFDKNAREDFLDNAASLAFDN
What is the function of this protein?
Fatty-acid-binding protein.  Interacts preferentially with saturated fatty acid.  May be involved in alpha-linolenic (C18:3) metabolism.
What are the official names of this protein?
Fatty-acid-binding protein 1, AtFAP1, Chalcone-flavanone isomerase family protein 1.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RUVA_AMOA5
Sequence: MIAYIQGSITYKSPTQLIVDVGGIGYELQISLQTYDSLKDIAASCKIFTYLHITQDAHTLYGFSTIEEKQCFLQLLSVNGIGPRVAITILSALTPEALQQAIMTHDTITLQAVKGIGQKAAQRIILELQGKVGKVGNMLSLQPSGQEAIYQEALAALSKLGIHKSTAEKTVAAILKEHQGEITVESLIKLALKG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ILVC_ANAD2
Sequence: MATIYYDKDANLDLLKKRKVAIIGYGSQGHAHALNLRDSGVDVRVGLAAGSKSKAKAEGAGLRVLSVAEASKEADVIMVLIPDQTQKKVYDEEIAPHLSKGKALLFAHGFNIHFVQVRPPPDVDVLLVAPKGPGHMVRRQYQDGRGIPGLVAVHQDATGQAKAVGLAYARGIGCTRAGVLETTFKEETETDLFGEQAVLCGGAAALVKNGFEVLVEAGYQPESAYFECLHELKLIVDLMYEGGLAWMRHSISDTAEYGDYTRGPRVVDGRSKDEMRKILKEIQGGHFAKEFILENQAGGPTMARYRAAEAAHPIEEVGKRLRDMMSWIREAKKDSSDPGSR
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: DTX51_ARATH
Sequence: MCNPSTTTTTTGSENQESRTGLFLDLFSINSFEPTKRNLRHCENRGSPLMAEAVTEAKSLFTLAFPIAVTALVLYLRSAVSMFFLGQLGDLELAAGSLAIAFANITGYSVLSGLALGMEPLCSQAFGAHRFKLLSLTLHRTVVFLLVCCVPISVLWFNVGKISVYLHQDPDIAKLAQTYLIFSLPDLLTNTLLHPIRIYLRAQGIIHPVTLASLSGAVFHLPANLFLVSYLRLGLTGVAVASSITNIFVVAFLVCYVWASGLHAPTWTDPTRDCFRGWAPLLRLAGPSCVSVCLEWWWYEIMIVLCGLLVNPRSTVAAMGVLIQTTSFLYVFPSSLSFAVSTRVGNELGANRPKTAKLTATVAIVFAAVTGIIAAAFAYSVRNAWGRIFTGDKEILQLTAAALPILGLCEIGNCPQTVGCGVVRGTARPSTAANVNLGAFYLVGMPVAVGLGFWAGIGFNGLWVGLLAAQISCAGLMMYVVGTTDWESEAKKAQTLTCAETVENDIIKAVVASTIDGECDEAEPLIRITVLY
What is the function of this protein?
Functions as a multidrug and toxin extrusion transporter that negatively regulates plant disease resistance (PubMed:21762165).  Plays an important role in maintaining normal plant architecture, possibly by regulating local auxin biosynthesis (PubMed:24391508).  May act as a negative regulator of hypocotyl cell elongation in the light (PubMed:26160579).
What are the official names of this protein?
Protein DETOXIFICATION 51, AtDTX51, Multidrug and toxic compound extrusion protein 51, MATE protein 51, Protein ABNORMAL SHOOT 3, Protein ACTIVATED DISEASE SUSCEPTIBILITY 1, Protein ADS1, Protein ALTERED DEVELOPMENT PROGRAM 1, Protein ADP1, Protein NOVEL ION CARRIER 4, Protein NIC4.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein.
Protein: NDK_VIBPA
Sequence: MALERTFSIVKPDAVERNLIGEIYNRIEKAGLRIIAAKMVHLTEEQASGFYAEHEGKEFFQPLKEFMTSGPIMVQVLEGENAIARYRELMGKTNPEEAAAGTLRADYALSMRHNSVHGSDSPESAAREIEFFFPESEICPR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UTP25_SCHPO
Sequence: MAIESDLDGASMDELAGKSYEALLYLMNKNKKRKPEKKDDKEKSSKKVQKKNKVIESLNEMEVEMEDENENENDEQEAIQYYINVESQDADETLHQEAQDSSEDPFHQHFDYDDSEVIKNSIAAYDEGKLCKSIEESKLGVSQSFFPDVTKRLPCSCLSEIKNIDDLGLKQRILDSYKKQKPSGQLTSMQIELAKAMFNYQDVFFTNMSMKSHKLGTSLLALHALNHVFKTRDRVLKNSARISQNPELEFRDQGYTRPKVLILLPTRNSAFEFINLLISYSGTNQVENRKRFDNEFSIEKEVISEKKPEDFRYLFSGNTDDMFRLGVKFTRKTVKLFSQFYNSDIIVASPLGLRLAIGNKGDKKRDLDYLSSIEIAMVDQAHALVMQNWEHIECIFDELNGLPKEAHGCDFSRVRPWYLDQQARYMRQTILFSQYNNLDINSFFSHYMSNIAGKVKFRSLLHGVLNRLGYKVTQTFVRISVDSIIKVPDARFSYFTGSILVQLKKYSQSGILVYIPSYFDFVRVRNYMDEEGINYSAISEYSSVSDMTRARNLFYQGRTNIMLYTERAHHFRRFDFRGVKAVVMYGPPTNPQFYVELVRMPMRTISEGNLDSDAAKCRIMYTKFDSICLEGIVGYQRVSNMCHGKHEVFEFL
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
Protein: BFPA_ECO11
Sequence: MVSKIMNKKYEKGLSLIESAMVLALAATVTAGVMFYYQSASDSNKSQNAISEVMSATSAINGLYIGQTSYSGLDSTILLNTSAIPDNYKDTTNKKITNPFGGELNVGPANNNTAFGYYLTLTRLDKAACVSLATLNLGTSAKGYGVNISSENNITSFGNSADQAAKSTAITPAEAATACKNTDSTNKVTYFMK
What is the function of this protein?
Major repeating bundle-forming pilus (BFP) subunit.  Is required for EPEC localized adherence.
What are the official names of this protein?
Major structural subunit of bundle-forming pilus, Bundle-forming pilin, Bundlin.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: ASTB_SHELP
Sequence: MKHYEANFDGLVGPTHNYAGLSYGNVASLNNAAAISSPKAAAKQGLKKAKALADLGLAQGMLAPQERPDLHTLRRIGFSGTDAEVLNKAAKQAPALLRACCSASSMWTANAATVSPSADTHDGKIHFTPANLVDKLHRSIEPVTTGNILAATFNNSRYFHHHQHLPEHVSFGDEGAANHTRLCSEYGHAGIELFVYGQEATNPNAPKPKKYPARQTLEASQAIARLHQLDDESSVFIQQNPDVIDQGVFHNDVIAVGNQNVLFYHEQAFVDTQKKLAEIQDKFNGKELHFIEVPTAKVGIQDAVKSYLFNTQIVTLPNGEMAIIAPTNCQENEAVYAYLNELVTLGTPIKQVHYFDVKQSMQNGGGPACLRLRVAMNETELAAVNPNTLMNDELFNRLNLWVEKHYRDELAIDDLADPQLIVESRTALDELTQIMKLGSVYQFQK
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: VPC37_MYCTU
Sequence: MKIVDANVLLYAVNTTSEHHKPSLRWLDGALSGADRVGFAWVPLLAFVRLATKVGLFPRPLPREAAITQVADWLAAPSAVLVNPTVRHADILARMLTYVGTGANLVNDAHLAALAVEHRASIVSYDSDFGRFEGVRWDQPPALL
What is the function of this protein?
Probable toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Upon expression in M. smegmatis inhibits colony formation.  The putative cognate antitoxin is VapB37.
What are the official names of this protein?
Ribonuclease VapC37, RNase VapC37, Toxin VapC37.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
What are the subcellular locations of this protein?
Secreted. Note=Following 6 weeks of nutrient starvation.
Protein: HA22I_ARATH
Sequence: MIGSFLTRGLVMVLGYAYPAYECYKTVEKNRPEIEQLRFWCQYWILVACLTVFERVGDAFVSWVPMYSEAKLAFFIYLWYPKTRGTTYVYESFFRPYLSQHENDIDHSLLELRTRAGDMAVIYWQRVASYGQTRILEILQYVAAQSTPRPQPPQKRGGRANQAPAKPKKAPVPQSEPEEVSLSSSSSSSSSENEGNEPTRKVSGPSRPRPTVTSVPAADPKNAGTTQIAQKSVASPIVNPPQSTTQVEPMQIEEVEGEAESGNENPNPEGPKETVMEETIRMTRGRLRKTRSEESR
What are the official names of this protein?
HVA22-like protein i, AtHVA22i.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
Protein: MUTH_SALNS
Sequence: MSALCPLLTPPASEALLLAQARQLSGYTLGELAAMAGITTPKDLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWVPVEGDRSIPLAERRVGSPLLWSPSEEEDRQLRLDWEELMDMIVLGQVERITARHGEVLQLRPKAANARALTEAIGARGEPILTLPRGFYLKKNFTQALLARHFLLQNP
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_CAUSK
Sequence: MIFPNIDPIVHIGPWALQWGPLALRWYALAYVVGILLGWRYAVMLVRDAKLWGGHKPTATPLQIDDLVLWITLGIILGGRIGYVLFYMMLNEGQRAGLAEHPFDVFKIWEGGMSFHGGFLGVCAAIVLFARQQKIDMLKLGDLIAPVAPIGLFFGRCANFINGELWGRETTHPWGMIFCNETIQKANQGGCPAGHLPRHPSQLYEAALEGVLLFLILNFAAHKLKWLQRRGALVATFLICYGLFRVSLEGVRNPDHGMPNFPLGLTMGMILSIPMLAVGVWLLWRALREPVPPPLAEDHEPA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YDIB_ECOBW
Sequence: MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEFFDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVNDISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CCM1_CANAL
Sequence: MIRLIRWNNVQSLVFKRCLFVPSNSLTNKRKRRIPPSKPRSSNRKDGDIEPYRMTDQNQTPNTGSIARLPAEVKKELKDLRSFTKVIAQHLKPEQENDSLTSAEKPDTSQLPPIDIEEATDDIFGEISGTKKLSANAVPPPPPPPGLDIPDEIKERLGLLSELLVPAKTSNNKLPEKQVENNWKLLLSQLDQAGGLSGLSKRSVSKFFSKIPPKNLKNLIPMIENMYNKAEMSIPHPIYYMFVRSLTLGDKISDSQMQLINKYFQEISKQTDLKIDHYETMILAYVKNNHMEKIDGILAQMKKKNIEISKMIYTSIVRGYIFYQKDHQRALDTFDSMKFLSQKTQPDEKVYTDVIVSCVMHREIERALDLYYELKDKGMNVNQNLLSTLAKGCSRSKQFKTQAWNFLFQVYDHGWVPNLQTYEHMLYIAARDGDVELTRVLFYKMLQTNSVTIRAFRYLILSYSKYVPPHKRKEKHLILLNHKGQLFRQNILQDVDFSKPVHGFPFLPSSHIPDSKFVLAESSAIWAHTVMNNPSFLRQQTLVASYVSIALELGDFTEFKDRFDSASYLNTDGIPKVREIEIIEPRQDEPTEKATTTEEQNASSETDNNSLIRSPILNQLQQNINDNQFKAPRDSYLYNLAIKAAGKFKNYGFAQEILHERGQFRKSNSFKLLSPKQQNQDDFQFAGYLVECWTNMNLLEDAYAVVLSSVDRFPWSWRELGVLNNAAMKLGSLELAEAVRKVAQVTQVKHHGKIKRQDFKTYVMKRGY
What is the function of this protein?
RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts.  Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity).
What are the official names of this protein?
Mitochondrial group I intron splicing factor CCM1.
What is the protein family that this protein belongs to?
Belongs to the CCM1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PG117_VARV
Sequence: MDAVIRGNDVIFVLKTIGVPSVCRQNEDPRFVEAFKCDELERYIKNNPECTLFESLRDEEAYSIVRIFMDVDLDACLDEIDYLTAIQDFIIEVSNCVARFAFTECGAIHENVIKSMRSNFSLTKSTNRDKTSFHIIFLDTYTTMDTLIAMKRTLLELSRSSENPLTRSIDTAVYRKKTTLRVVGTRKNPNCDTIHVMQPPHDNIEDYLFTYVDMNNNSYYFSLQRRLEDLVPDKLWEPGFISFEDAIKRVSKIFINSIINFNDLDENNFTTVPLVIDYVTPCALCKKRSHKHPHQLSLENDAIRIYKTGNPHSCKVKIVPLDGNKLFNIAQRILDTNSVLLTERGDHIVWINNSWKFNSEEPLITKLILSIRHQLPKEYSSELLCPRKRKTVEANIRDMLVDSVETDTYPDKLPFKNGVLDLVDGMFYSGDDAKKYTCTVSTGFKFDDTKFVEDSPEMEELINIINDIQPLTDENKKNRELYEKTLSSCLCGATKGCLTFFFGETATGKSTTKRLLKSAISDLFVETGQTILTDVLDKGPNPFIANMHLKRSVFCSELPDFACSGTKKIRSDNIKKLTEPCVIGRPCFSNKINNRNHATIIIDTNYKPVFDRIDNALMRRIAVVRFRTHFSQPSGREAAENNDAYDKVKLLDEGLDGKIQNNRYRFAFLYLLVKWYRKYHVPIMKLYPTPEEIPDFAFYLKIGTLLVSSSVKHIPLMTDLSKKGYILHDNVVTLPLTTFQQKISKYFNSRLFGHDIESFINRHKKFANVSDEYLQYIFIEDISSP
What is the function of this protein?
Multifunctional protein required for genome uncoating and replication.  Major viral uncoating protein that is required for the release of the viral genome from incoming viral cores containing the viral DNA genome.  Possesses an ATPase activity that is required for hexamerization and uncoating.
What are the official names of this protein?
Uncoating factor OPG117.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG117 family.
Protein: G6PI_MYCPA
Sequence: MTSVHTLPDITATPAWDALRKHHDRIGDTHLRQFFEEDPDRGRELTVTVGDLYIDYSKHRVTRETLRLLVDLARTAKLEERRDQMFAGVHINTSEDRAVLHTALRLPRDAELIVDGRNVVADVHEVLDAMGEFTDRLRSGEWTGATGKRISTVVNIGIGGSDLGPVMVYQALRHYADAGISARFVSNVDPADLIATLADLDPATTLFIVASKTFSTLETLTNATAARRWITDALGDAAVAHHFVAVSTNKRLVDDFGINTDNMFGFWDWVGGRYSVDSAIGLSVMAVIGREAFADFLSGFHIVDRHFQTAPLESNAPVLLGLIGLWYSNFMGAQSRAVLPYSNDLARFAAYLQQLTMESNGKSTRADGSPVTTDTGEIFWGEPGTNGQHAFYQLLHQGTRLVPADFIGFSQPIDDLPTAEGSGSMHDLLMSNFFAQTQVLAFGKTAEEIAAEGTPADIVPHKVMPGNRPSTSILANRLTPSVLGQLIALYEHQVFTEGVIWGIDSFDQWGVELGKTQAKALLPVITANNSPAPQSDSSTDALVRRYRSERGRTS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_AZOPC
Sequence: MNKIHAVITGIGGYVPEYKLTNEEISTMVDTSDEWILKRIGIKERRILKPEEGKGITYLALKAIEDLKSRHDFDPLEIDAVLFATATPDYPFPNSASLIAHKVGITNAFGFDMEAACSGFIYALEVAQGFIVSGKHKKVMIIAGDVLSVFIDYSDRNTSPIFGDGCGCALVEATMEDIGLVDSIMRCDGSIPESLHVYGGGSVNPTTYETINNKLHYVWQDGKVVFRHAVSNMADTCQKLISKNNLSKDEIDWVVPHQANLRIIDAVTNHLKISRERVMINIEKYGNTGAASIPLCLCEWESKLHKGDKMIFTAFGAGFTWGATYLKWGYDSH
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR22_MOUSE
Sequence: MCFSPVLEINMQSESNVTVRDDIDDIDTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLINSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLESNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMTSIWIFSFFSFLIPFIEVNFFSLQSGNTWANKTLLCVSTSEYYTELGMYYHLLVQIPIFFFTVIVMLITYTKILQALNIRIGTRFSTGQKKKARKKKTISLATHETTDMSQSSGGRNVVFGVRTSVSVIIALRRAVKRHRERRERQKRVFKMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPMPNNAVIHNSWIDPKRNKKVTYEDSEIREKCLVPQVVTD
What is the function of this protein?
Orphan G-protein coupled receptor.  Seems to act through a G(i)/G(o) mediated pathway (By similarity).  May be involved in ciliogenesis (By similarity).
What are the official names of this protein?
G-protein coupled receptor 22.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDC2_STRMU
Sequence: MKKIYKRLLFSGLALSMLFFLSGCVQMKNGKPTGEGWVYKFFAAPMGSVIQYLANNLGLGFGFAIIIVTVIVRLLILPLGLSQVRKMTYQSEKMAYLKPVFDPIQERMKNAKTQEEKMAAQTELMQAQRHYGMSMFGGLGCLPLLIQMPFFSALYISTRYTKGIASASFLGIKLGSPNMIITVIIGILYLVQSWVSTLSVPEAQRQQTRNMMFMMPIMMVMISIGAPAGGALYWLVSGIFGLIQQLITNHIIKPKLRKQIDEEFKKNPPKPFKSNARKDITPQANNDKKLITSKKQKSNRNAGKQRHHKQ
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity).  Partially complements an E. coli yidC depletion experiment.
What are the official names of this protein?
Membrane protein insertase YidC 2, Foldase YidC 2, Membrane integrase YidC 2, Membrane protein YidC 2.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MVPA_DICDI
Sequence: MADLNSVIRIKPFHFIHVLDNNTNVTRVEVGPQTFTRQDHEKLVSGPEPMIMIPQRNYCTISNPVVRNENGSLVLDEYGQVKLRHGDEEIRFSQEPFPLYPGEKISGKVTALQVVAPLKALRLRALRDFTEAKVTHVAGDEWLFEGPATYLPRIDVRIEEEIKATIIGPNQALKLRANKACSDRSGVARKAGEEWLVRQHGAYLPGVDEKVVEIVNAYVLTDKKALHLKATKTFLDETRKTQRKAGEEWLVVSTDAETHIPDVYEQVVGEVHITTLSNRQYCVVLDPIGANGKPQLGHKQLRKGELAFFLNPGESLEGNKIHNIYVLTEQEALLLRAKETFSIDGESHLAGDRWMIYGPCDYVPPVQVEVVEKRESIPLDENEGIYVRDIKTGKVASIKGQSYMLKANEELWEKVLPRTVEEVLAKESLNPEFTDNRDSTRVVTYRAPHNSAVQIYDYKEKKSRVVFGPDLVMLGPDEHFTVLSLSGDKPKRPHQIKAIALFLGPDFMTDVVIVETSDHARLSLKLSYNWEFKVDRSKIEDAQKIFQVPDFVGDSCKAIASRVRGAVAAVSFDDFHKRSAEVIRQSVFGLDESGEVRKNFSFNSNNLVITNIDIQSVEPVDQRTRDSLQKSVQLAIEITTKSQEAAARHEAERLEQGARGRLERQKIHDEAQAELARKDLLQLQAQSAAVESTGQATAEAQATAEAANIAAEANVKQAELKAQATKIRSESEISLLKAKRENELSYQKSIDELELTKQSDLAEIEASKFKAIVESIGRDTLKSIACAGNEMQAKLLQGLGLKSFMITDGKSPLNLFDTANGIIGNNNQMVNMSNAAKQSGRRN
What is the function of this protein?
Unknown, though MVP-alpha is required for normal vault structure.
What are the official names of this protein?
Major vault protein alpha, MVP-alpha.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CRFA2_CONSP
Sequence: GPMEDPLEIIRI
What is the function of this protein?
In contrast to other conorfamides, this peptide does not show activity on human and mouse sensory neuron-specific G-protein coupled receptors MRGPRX1 (PubMed:30243794).  In vivo, it causes hyperactivity when injected intracranially into mice, and when injected into the foot of the fresh water snail P. paludosa (PubMed:18201803).  It also causes paralysis when injected into the foot of the limpet P. opea (PubMed:18201803).  Has no effect when injected below the rear part of the dorsal fin of the fish L. reticulatus (PubMed:18201803).
What are the official names of this protein?
Conorfamide-Sr2, CNF-Sr2, Cono-RFamide-Sr2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS7_METTE
Sequence: ELIGAANRDTKSFSINRKDAKERVAKAAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center (By similarity).
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.