PharMolix/UniProtQA huggingface dataset:
Protein: PLCG1_HUMAN
Sequence: MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL
What is the function of this protein?
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3).  Plays an important role in the regulation of intracellular signaling cascades.  Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).  Plays a role in actin reorganization and cell migration (PubMed:17229814).
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, PLC-II, Phospholipase C-gamma-1, PLC-gamma-1.
What are the subcellular locations of this protein?
Cell projection, lamellipodium. Cell projection, ruffle. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.
Protein: RECA_SHEB8
Sequence: MKVDPNKEKALAAVLIQIEKQFGKGSIMKLGEDRSMDVETISTGSLSLDVALGAGGLPMGRIVEIYGPESSGKTTLTLEVIAAAQREGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKDGDEVVGNETRVKVVKNKVAAPFKQAEFQILYGQGINRTGELVDLGVAHKLIEKAGAWYSYKGDKIGQGRANAGKYLTENPAIATEIDKTLRELLLSNPSALAAKADASTEDNVDLETGEVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_LACPL
Sequence: MGQKVNPTGLRVGIIRDWEAKWYAEKDFAAYLNEDLRIRKYIEQRLADASVSTVEIERAANRVNISIHTAKPGMVIGKGGSEVEALRKELNNLTGKRVHINIIEIKKPDLDAKLVGESIARQLEGRVAFRRAMRGAMQRTMRSGAKGIKTQVAGRLNGADMSRVEAYSDGTVPLHTLRADIDYSWVEARTTYGKLGVKTWIYRGEILPEKKSAKGGN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PMTP_ARATH
Sequence: MAMGKYSRVDGKKSSSYGLTITIVLLLSLCLVGTWMFMSSWSAPADSAGYSSTDTAKDVSKNDLRKEEGDRDPKNFSDEKNEENEAATENNQVKTDSENSAEGNQVNESSGEKTEAGEERKESDDNNGDGDGEKEKNVKEVGSESDETTQKEKTQLEESTEENKSEDGNGNEEKAEENASETEESTEKSSKEVFPAGDQAEITKESSTGDGAWSTQLVESQNEKKAQQSSISKDQSSYGWKTCNVTAGPDYIPCLDNWQAIKKLHTTMHYEHRERHCPEESPHCLVSLPDGYKRSIKWPKSREKIWYNNVPHTKLAEIKGHQNWVKMSGEHLTFPGGGTQFKNGALHYIDFIQQSHPAIAWGNRTRVILDVGCGVASFGGYLFERDVLALSFAPKDEHEAQVQFALERGIPAMLNVMGTKRLPFPGSVFDLIHCARCRVPWHIEGGKLLLELNRALRPGGFFVWSATPVYRKNEEDSGIWKAMSELTKAMCWKLVTIKKDKLNEVGAAIYQKPTSNKCYNKRPQNEPPLCKDSDDQNAAWNVPLEACMHKVTEDSSKRGAVWPNMWPERVETAPEWLDSQEGVYGKPAPEDFTADQEKWKTIVSKAYLNDMGIDWSNVRNVMDMRAVYGGFAAALKDLKLWVMNVVPVDAPDTLPIIYERGLFGIYHDWCESFNTYPRTYDLLHADHLFSTLRKRCNLVSVMAEIDRILRPQGTFIIRDDMETLGEVEKMVKSMKWKVKMTQSKDNEGLLSIEKSWWRPEETETIKSAIA
What are the official names of this protein?
Probable methyltransferase PMT25.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RL19_GEOSW
Sequence: MMHHLIQEITKEQLRTDLPDFRPGDTVRVHVKVIEGNRERIQVFEGVVIKRRGAGISETFTVRKVSYGVGVERTFPVHTPKIAKLEVVRRGKVRRAKLYYLRQLRGKAARIKEIVR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: KNG1_HUMAN
Sequence: MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRITEATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFSVATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLRIASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPWEKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSGKEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLDDDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQEKTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSFNPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS
What is the function of this protein?
The active peptide bradykinin is a potent vasodilatator that is released from HMW-kininogen shows a variety of physiological effects: (A) influence in smooth muscle contraction, (B) induction of hypotension, (C) natriuresis and diuresis, (D) decrease in blood glucose level, (E) it is a mediator of inflammation and causes (E1) increase in vascular permeability, (E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e. g.  prostaglandins), (F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action).
What are the official names of this protein?
Kininogen-1, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight kininogen, HMWK, Williams-Fitzgerald-Flaujeac factor.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: H2R01_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLFECSVSCEIGKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1j, U4-TRTX-Hhn1j, Hainantoxin-II-18, HNTX-II-18.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1961_SULIA
Sequence: MPISGVDDGYFPLSYKGGKGKTALVVVTFYDYEMIDLDWGLITVDGNDATDVLKQLRKGDIVILDGVIFAGFNYIVPYSDNMIFFYSKMPKVDLIKNALMKHFQADTERVREILYVLNNLKQIPTKRGNVFLYSTVELSLAKSIIEKYQIYSKIPEVLKSAHVIASSLGRFLARYKKTI
What are the official names of this protein?
UPF0215 protein M1627_1961.
What is the protein family that this protein belongs to?
Belongs to the UPF0215 family.
Protein: Y329_METJA
Sequence: MEDDKIQMETVSIDLAKDTAVNMALRILFTQIFTPYSIVSIDGKQLSKDVIDEISGLIDRHIRDLQLAFSDFLLKGKCYLYKLHYINPNSMNFKERKHWNPQKGRYEYCITYTIKRNNAERWWEVDTEEDVRVVIAPMELRQHFPADVEFYDEKYLGVYYNPIPIHETIQEIADQKNTLALKVLPLMVQKTLIPTIIGITQNTKAGEIIKKALSNHQNRTRVYIPATPDEVKFETISIGKDIPTDLIETMLYYYDSAIFMGLGTSISIVKASGQELTTSRTVDRNILRIVQGYQQEIERWIADQLEKMGYKGIWVKFANPDPDWEINMLQKAKMVAELKAQEQVAKYDFSALIERIFPSNEFGEILAAYPDLTEKEVEKLLKMAKEGKGGLEYADEEKQKLLEKKRKSLEKIISKLEKVGDKFGKKSMENFVNWILETYERLGYNELMQDWDELLREFTREEVDMFFLDYVAPTLNSLKIYDDLDQQTIDILKQHWEQAFYNIYSSYSQQFLDVLTEGIQKGLGEEEIAKNLKKVAKDVKGSRLQMRAREEMNKTYNLTRARRFWNDKVIYVTMKDERVRPSHRKLHGLIFVPAERPELVPPLGYGCRCTITPVRD
What are the official names of this protein?
Uncharacterized protein MJ0329.
Protein: APT_YERPG
Sequence: MTVSASKTAQQLKYIKDSIKTIPDYPKAGILFRDVTSLLENPKAYSASIKLLSEHYSESGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRETISESYELEYGTDTLEIHTDSIQPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVVHAAFIINLPELGGEARLTQQGIHCYSLVSFDGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y036_TREPA
Sequence: MLQYAFMRNAFVASFLIALLCPLVGMHLVLRRYALMGDALAHGSLAGVSIAVSCGIHPGWGSFFFTALVGVLIEFLRAFFKNHHDLILSIVLSLSVGIAVTLLSSGLIQADIDSYLFGSILVVSTRDLWIMLALSVFCVGTLALRYHQLLYLAFDEETARICGVAADGINYVASVVISATIAASIKITGILVLSSLMTVPVATALQLRVGFLLTLVAAFLFSMLDTALGLVFSYYLNVAPGGFTALVSVVVLMLVIALTQVGRART
What is the function of this protein?
Part of an ATP-driven transport system TP_0034/TP_0035/TP_0036 for a metal.
What are the official names of this protein?
Probable metal transport system membrane protein TP_0036.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2508_CUPTR
Sequence: MTISKWPACERPREKLLESGAAALSDAELLAVLLRVGAAGKSAVDLARELLHRFGSLTALFAAQGQALAGVRGMGAAKFAQVQAIPELARRALAESLRLPSGFDSPDSVRSYLRLTLAPLQHEVFMCLFLDPGNRMVASEELFRGTLTRTSVYPREVARQALAHNAAGIIVAHNHPRGTTAPSQSDIHLTRELARTLDLIDVRLLDHFIVAGHEIRSLAESCERLPGL
What are the official names of this protein?
UPF0758 protein RALTA_A2508.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RECR_VEREI
Sequence: MSSSNALDALIQALRRLPGVGVKSAQRMAFHLLQHDRAGGQALAQALHDALGSVQHCARCHTFTEAETCRTCLDPGRDATRLCVVETPADQAALERTGAFKGLYFVLMGRLSPLDGVGPKEIGLQKLIARATEGGVQEVILATNFHAEGEATAHVISQALKRQGLHVTRLARGVPVGSELEYVDLGTIAHALVDRR
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SPB10_PLEMO
Sequence: MDALATSINQFALELSKKLAESAQGKNIFFSAWSISASLAMVHLGAKGNTAAQMAQVLQFKRDQGVKSDPESEKKRKTEFNLSNSGEIHCNFQTLISEILKPNNDYILKTANAAYSEKTYPFHNKYLEDVKTYFGAEPQSVNFVEASDQIRKEINSWVERQTEGKIQNLLSDDSVGSTTRMVLVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKEKLQIFHIEKPQALGLQLYYKSCDLSLFILLPEDINGLEQLEKAITYEKLSKWTSADMMEVYDVQLHLPKFKLEESYDLKSTLSSMGMSDAFSESEADFSGMSSARNLFLSNVFHKAFVEIDEQGTEAAAGSGSEISFRIKVPSIEFNANHPFLFFIRHNKTNNILFYGRFCSP
What is the function of this protein?
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF.  May regulate protease activities in the cytoplasm and in the nucleus (By similarity).
What are the official names of this protein?
Serpin B10.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GATA_LISIN
Sequence: MGLFDFSVKELHDKLVKKEITPFDLVTESFNRIEAVEDKVGSFITLNKETALGVAEELGDAGIDPNNMLAGLPIGIKDNIVTKNLRTTAASKILENFDPIYDATVVSKLKNAQTINIGKLNMDEFAMGSSTETSYFHKTHNPWDLSRVPGGSSGGSASAVAAGEVLFSLGSDTGGSIRQPAAFCGVVGMKPTYGRVSRFGLIAFASSLDQIGPITKNVEDNAYLLEAISGLDANDSTSINQPVERFSDSLTGDIKGLRIGVPKEYLGEGVDPGVKQAVLDALKTLEKLGATWDEVSLPHSEYGVASYYILASSEASSNLSRFDGVRYGYRSPNATTLEELYTKTRSEGFGDEVKRRIMLGTYALSSGYYDAYYKKAQQARTLIKQDFVDVFKNYDVIIGPSSPTTAFKIDGMINDPITMYSNDILTVPINLAGVPAISVPCGFSEGLPVGLQIIGNYFEESLLYKVAHAFEQETTFHKEKPNL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: HBE_SMICR
Sequence: MVHFTAEEKNAITTIWGKVNVEETGGEALGRLLVVYPWTQRFFDSFGNLSSASAILGNPKVKAHGKKVLTSFGDAVKNLDNLKGTFSKLSELHCDKLHVDPENFRLLGNVLVIVMAAHFNKEFTPEVQAAFQKLVTGVANALAHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin embryonic beta chain, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TRPD_BORBR
Sequence: MTIAAAEALTRCIEHREIFHDEMLHLMRLLMRGELSPQIASALLMGLRVKKETVGEITAAAQVMREFATPVVTPNPQDLLDMCGTGGDGSHTFNISTTAMFVAAAAGVPIAKHGNRSASSSSGSADVLEALGANLQLTPEEVAECVAATGIGFMFAPAHHGAMKNVAAVRKELGVRTIFNILGPLTNPAGAANQLMGVFHPDLVGIQVRVLERLGSRHVLVVHGKDGMDEASLGAATMVGELKDGVVREYEIHPEDYGLSMMSNRGIKVSNREESRALVIEALDNVDGVARDIVALNAGLAIYAGNKADSIPEALALAFETISNGSARAKLEEFCAYTRKFQK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: PIMT_RAT
Sequence: MAWKSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKSNPYMDSPQSIGFQATISAPHMHAYALELLFDQLHEGAKALDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKDDPMLLSSGRVRLVVGDGRMGFAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVGPAGGNQMLEQYDKLQDGSVKMKPLMGVIYVPLTDKEKQWSRWK
What is the function of this protein?
Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins (By similarity).  Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin C-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein (By similarity).
What are the official names of this protein?
Protein-L-isoaspartate(D-aspartate) O-methyltransferase, PIMT, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl/D-aspartyl methyltransferase, Protein-beta-aspartate methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL23_PSEPW
Sequence: MNQERVFKVLLGPHVSEKATVLAEKKGQFVFKVATDATKLEIKKAVEGLFNVKVENVSTVNVLGKTKRTARGLGKRNDWKKAIVSLQPGQDLDFSSSAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: UVRB_ECO24
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLEB_CALRH
Sequence: DFRCPTTWSASKLYCYKPFKEKKTWIEAERFCAKQAENGHLVSIGSAAEADFLDLVIVVNFDKQRYRAWTGLTERNLKWTNGASVSYENLYEPYIRKCFVVQPWEGKSKWYKADCEEKNAFLCKFPKPH
What is the function of this protein?
Potent inhibitor of collagen-induced platelet aggregation.  It acts by binding to the integrin alpha2A domain and blocks collagen binding to integrin alpha-2/beta-1 (ITGA2/ITGB1).  The gamma/delta subunits mainly contribute to this activity.
What are the official names of this protein?
Snaclec rhodocetin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: VHLP_ASFWA
Sequence: MSAKKKPTITKQELYSLVAADTQLNKALIERIFTSQQKIIQNALKHNQEVIIPPGIKFTVVTVKAKPARQGHNPATGEPIQIKAKPEHKAVKIRALKPVHDMLN
What is the function of this protein?
DNA-binding protein that plays a critical role in nucleoid compaction, genome replication and DNA replication and transcription (By similarity).  Binds to both ssDNA and dsDNA with a binding site covering about 15 nucleotides (By similarity).  Displays DNA-supercoiling activity only when associated with the viral DNA topoisomerase 2 (By similarity).
What are the official names of this protein?
Viral histone-like protein, DNA-binding protein pA104R, pA104R.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: DNAT_ECO8A
Sequence: MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELTSFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPKRDVNTVSEPDSQIPPGFRG
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: TRUB_BURP1
Sequence: MARRALDGVLLLDKPVGLSSNDALMRAKRLYQAKKAGHTGTLDPLASGLLPLCFGEATKFSQDLLEADKTYEATMRLGVRTTTGDAEGDVLDTRDVSCDEAAVRAALARFVGEIVQVPPMYSALKRDGKPLYEYARAGQTVEREGRTVTIRALALVSCALPDVTFRVTCSKGTYVRTLAEDIGEALGCGAHLTMLRRTGVGPLTLEHAVTLDALDAATQDERDARLAPVDALLSTFPCVKLDAALATRFLHGQRLKLSELAARPDAAEGGRVRVYDADDRLLGVARASEGVLAPERLVVTGA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y3707_RHILW
Sequence: MNRPWKKSDDHVRLAIRLTPNGGRDAIDGAETDGEGEAYLKTRVTTVPEKGKANKALILLIAKSLGIAKSSVSLVSGDTARKKILRIDGDPEDLGKKLETLLG
What are the official names of this protein?
UPF0235 protein Rleg2_3707.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: SYC_PSET1
Sequence: MVNIYNTLTRQKEQFKPMVEGKIDMYVCGITIYDYCHIGHARTFVGFDVIVRYLRHIGYDLKYVRNITDVDDKIIKRANENGESINDLTVRMTKAMHEDFDSLNMLRPDVEPTVTAHMDEIIEMVERLITKGHAYVAADGDVLFDVSTFEQYGALSQQDLTMLQSGSRVEVAQDKDDPLDFVLWKKAKAGEPSWSSPWGEGRPGWHIECSAMSSKHLGEHFDIHGGGSDLQFPHHENEIAQSCCANNGKYVNTWIHTGMVQVNKEKMSKSLDNFFTVREVLKQYDAESVRYFLISGHYRSQLNYSQENLDQARSSLERIYTALRGVEPVACELDDNEYVIKFRKAMDDDFNTPEALPVLFELAKELNLVKDIDSQQAGQLAFILGSISEVLGVAQQDPEAFLQGGQDDDEVAQIEALIVKRNDARASKNWAAADEARDALSALGVILEDSAGKTTWRKA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAAB_BRASZ
Sequence: MKWSNKDGYPWSKIIHAEKFFDKVIQNDTRPGKWEWADVVSGLRDLDKDPRMNSERRYVAIVNEDVGLGETKGIGITPGLFCGCQLIHPGEEVTSHRHNSVALYFIVEGTGELEVEGEVYSYKPFDIMTCPAWSYHAWRATGDKDTLMYVIHDMALLAYMRALFWEEPKGSENIRHMVKGSTHTWSNTKAPEVSKTQAAKELLKQGE
What is the function of this protein?
Dioxygenase that catalyzes the cleavage of the aromatic ring of 5-nitrosalicylate (5NSA) without prior removal of the nitro group in biodegradation of 5-nitroanthranilate.
What are the official names of this protein?
5-nitrosalicylic acid 1,2-dioxygenase, 5NSA 1,2-dioxygenase, 5-nitroanthranilic acid degradation protein B.
Protein: SCPB_CLOP1
Sequence: MSDINQIEFSEISKKDELKSIIESLLFVSGEPLALKDICRIVEEDFKYVEDLMRELMNIYNGDSSRGIKIISLNGTYQLVTKTKNSEYVQKLLKKNVRQSLSQASLESLAIICYKQPITRVEIDEIRGVKSESAIQRLVEKNLVEETGRLEVPGRPILYGTTDEFLRHFALNDLGDLPSIELFEENDEVSDMVEE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: PURA_BIFA0
Sequence: MPGIVLIGAQWGDEGKGKATDLIGTKVDYVARFNGGNNAGHTVVVGDESYALHLLPSGIISPTATPVIGNGVVVDPEVLLEEIEGLESRGIDCSRLLVSESAHVIAPYHRMIDKVTERFAGKKKIGTTGRGIGPAYADKINRVGIRIADLFHEDVLRDKVSNALHQKNQMLVKLYNRRAFDVEATVQELLEVGVKLKPYVANTSLILNNALDDGKTVLFEGGQATMLDIDHGTYPFVTSSNPTAGGACTGTGVGPTKIDRVIGVSKAYVTRVGEGPFPTELFDENGEWLRAQGHEYGVTTGRPRRCGWFDAVVNRYATQVNGLTDIVLTKLDVLTGLDEIPVCVAYDVNGVRYDDMPTDQSAFAAAKPIYGMMPGWSEDISQVHAFEDLPQTCQDYVKRLEELSGCRISAIGTGPQRDHIIEVHSLLD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.