PharMolix/UniProtQA huggingface dataset:
Protein: THIG_XANOR
Sequence: MTTPSPSDALLIAGKRYRSRLLTGTGKFKDLDETRLATEAAAAEIVTVAIRRVNIGQDPNAPSLLDVLPPDRYTLLPNTAGCYSAEDAVRTCRLARELLDGHNLTKLEVLGDERTLYPDVVQTLKAAEQLVADGFEVMVYTSDDPILAKRLEEIGCVAVMPLAAPIGSGLGIQNKYNLLEIIENAKVPIIVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPILMASAMRKAIEAGREAFLAGRIPRKRYASASSPVDGVIG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_MYCUA
Sequence: MPPKKASGTGPKKGQKTRRREKKNVPHGAAHIKSTFNNTIVTITDPQGNVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAQEHGVRKVDVFVKGPGSGRETAIRSLQAAGLEVGAISDVTPQPHNGVRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TARP_STAAN
Sequence: MKKVSVIMPTFNNGEKLHRTISSVLNQTMKSTDYELIIIDDHSNDNGETLNVIKKYKGLVRFKQLKKNSGNASVPRNTGLKMSKAEYVFFLDSDDLLHERALEDLYNYGKENNSDLIIGKYGVEGKGRSVPKAIFEKGNVAKADIIDNSIFYALSVLKMFKKSVIDKNKIKFKTFSKTAEDQLFTIEFLMNSKNYSIKTDYEYYIVVNDFESSNHLSVNKSTGNQYFATINEIYKAIYKSPIYKNQEKRHQLAGKYTTRLLRHGQKKNFANSKMKYEDKIEWLNNFSKTINKVPRDSDKYVTQIFNLKLEAIRQNDLLAVMIADKLL
What is the function of this protein?
Attaches beta-O-GlcNAc (beta-O-N-acetyl-D-glucosamine) residues to the C3 position of poly(RboP)-wall teichoic acids (WTAs).  Attenuates immunogenicity of WTA and protects S. aureus against adaptative host defenses by allowing bacteria to evade recognition by preexisting anti-S. aureus antibodies.  Also protects the cell from podophage infection.
What are the official names of this protein?
Poly(ribitol-phosphate) beta-N-acetylglucosaminyltransferase TarP, WTA glycosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: DHH1_CRYNB
Sequence: MASSSTLLNDDWKQGLAAPPKDLRPQTEDVTATQGSRFEDFGLRRELLMGIYTAGFERPSPIQEQAIPMALTGRDILARAKNGTGKTASFIIPTLNRINTSLSHIQALILVPTRELALQTSQVCKTLGAHIPNLQVMITTGGTTLRDDILRLQQPVHILVGTPGRILDLGSKGIASLNKCGVFVMDEADKLLSEDFMPVIEQTLALCPQERQVMLFSATFPWTVKEFKDQHMVQPYEINLMDELTLKGVTQYYAYVEESQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKVTELGYSCFYSHAKMQQAHRNRVFHDFRNGMTRNLVCSDLLTRGIDIQAVNVVINFDFPRTAESYLHRIGRSGRFGHLGLAISLLTLEDRHNLYRIESELGTEIAPIPAVIDPVLYVAPAMVEEERESPPPKPAAIAAPPAQQQPQQRQRQHPPVPSHQAAQQSPAAAPVQQQQQQQQQQQQQQQQQQPQYQQAYGQGPPQPQALFQQQPNSSPAPAPLPSYSQQAPTQAQGPAPVQSPPPAPSTQPQAPAQTPIQGQIPPTQPRAQQQGQQQPGQPGQAQGQSQPNRRPNTGGFRGNGRGQGHRGRGRGRGGQPGQPGAGAGAGQSQQAQA
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.  Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs.  May also have a role in translation and mRNA nuclear export (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DHH1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: RS17_METAR
Sequence: MAKDIGLNVKAPKTECNDPQCPFHGSLAVRGQIFEGTVVSAKMSKSVVVSREYLKRDLKYDRYEKRRSKLHAHNPPCINAKEGDKVVIAECRPLSKTKTFVVVEVAGHESN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SAFA_ECOLC
Sequence: MHATTVKNKITQRDNYKEIMSAIVVVLLLTLTLIAIFSAIDQLSISEMGRIARDLTHFIINSLQG
What is the function of this protein?
Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions.
What are the official names of this protein?
Two-component-system connector protein SafA.
What is the protein family that this protein belongs to?
Belongs to the SafA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: SYM_PSET1
Sequence: MAQRKILITSALPYANGPTHLGHLLEYIQTDIWSRFQKLQGHEAYYVCADDAHGTPIMLNAQKQGITPEEAVEKVSIERQRDFADFNIKFDNYHSTHSQENKELSELIYNRLNDAGHIKRHTISQLFDPEKGIFLPDRFVTGTCPTCKSENQNGDNCDSCGATYSPTDLINPRSVMSGAEPILKDSEHYFFDLPAFEGMLKEWLHSGTIQQEMANKLDEWFTDGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMASFKNLCDKKGIDFDAFWAADSDAELYHFIGKDIIYFHSLFWPAMLEGANFRKPTNVFAHGFVTVNGEKMSKSKGTFIKARTYLDNLNPEYLRYYYAAKLSGGIVDLDLNLEDFAQRVNSDLVGKVVNIASRCAGFITKKFDGKLSATVMQPQLLKEFQAAAPSITAHYENREFSRAIREIMALADKANQFIDAAAPWVLIKDETKQQEAHEVCSLGLNLFRVLITYLKPVLPEMADNVEAFLNDDLAWDGVQNALVSHPINKFKPLMQRVEMDKVNKMVEESKESLESKVTIDPNSPLAKEPICDEIEFDDFAKVDLRVAKIAKAEHVEGADKLLKLTLDLGGETRQVFAGIKSAYAPEDIEGKLTVMVANLKPRKMRFGMSEGMVLAAGPGGKEIYILNPDDGSEPGMRVM
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDT5_MYCTU
Sequence: MVIRVLFRPVSLIPVNNSSTPQSQGPISRRLALTALGFGVLAPNVLVACAGKVTKLAEKRPPPAPRLTFRPADSAADVVPIAPISVEVGDGWFQRVALTNSAGKVVAGAYSRDRTIYTITEPLGYDTTYTWSGSAVGHDGKAVPVAGKFTTVAPVKTINAGFQLADGQTVGIAAPVIIQFDSPISDKAAVERALTVTTDPPVEGGWAWLPDEAQGARVHWRPREYYPAGTTVDVDAKLYGLPFGDGAYGAQDMSLHFQIGRRQVVKAEVSSHRIQVVTDAGVIMDFPCSYGEADLARNVTRNGIHVVTEKYSDFYMSNPAAGYSHIHERWAVRISNNGEFIHANPMSAGAQGNSNVTNGCINLSTENAEQYYRSAVYGDPVEVTGSSIQLSYADGDIWDWAVDWDTWVSMSALPPPAAKPAATQIPVTAPVTPSDAPTPSGTPTTTNGPGG
What is the function of this protein?
Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem.  Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems.
What are the official names of this protein?
L,D-transpeptidase 5, LDT 5, Ldt(Mt5).
Protein: DGTL1_JANSC
Sequence: MRAAYACDPMATRGRAVVEEESAHRSPFQRDRDRIIHSSAFRRLKHKTQVFVEHEGDYFRTRLTHSLEVAQVARTMARALGLDEDLTETVALAHDLGHPPFGHTGEDALSALMAPYGGYDHNAQALRIVTHLERHYAEFDGLNLTWETLEGIAKHNGPVAAPLPWALEASCADINLELSTHASAEAQVAALADDIAYNHHDLHDGLRAELFSTDELAGLPILKGCFAAVDQRYPGLNYYRRRHEALRRFFGVLVEDVLANARAALAEINPQSAMDIRNAGRPIIRFSNGLFADLQVIRTFLFKRMYRAPSVVEMRTQVTQVVEDLFPFFLETPSELPRQWRKDVEDVAGDATQLARIVSDYISGMTDRFALQCHQRLIGGAQDGTVTGPSTLNFGA
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: OTC_META3
Sequence: MHLLTLENLERKDIENILNDAIYFKKNRKSENILKEKTVALIFESPSTRTRISFDIAVNELGGHSLTLNTGETHVSKKESTKDTAKVLSRFVDVIVARVKEHSTLEDFTKYGNVPVINALSDLSHPCQILADLLTIKEHKNKLSGLKFAYFGDGNNVCNSLILGCAIMGMDIFVATPEGYEPNEKFVKMAQQIIDKQGEGSITITDDAIICAKDADVLYTDVWVSMSDKNKNIDEVLKIFPPYQINEKLLSYAKKDAIVMHCLPANRGMEITDEVIDGEQSVVYDEAENRLHAQKAVFKYIFSK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_BORBU
Sequence: MLKAVLETTIGSKSKRDLKDYLPTLRNINKLERWALLLADEDFSKETEKLKDELKSGNSLENILERAFTLSREAARRRLKERPYDVQIIAGLALHKGKIIEMKTGEGKTLSSVQAAYLNSLTGDGVIIVTVNDYLAERDSNWMKPVFDLLGVSVGVVLSNMDYELRKAQYAKDITYVTNNELGFDYLRDNMRYDLNEKSLRKFNYCIIDEIDSILIDEARTPLIISGPTEGNTNAYLEVNSLVSFLKECSKDPKTGDYPLEIDDLDGDYTVDEKAKRISFTAKGLNNLEQLLVSKGIISGSMYTDSNFNYVHYMTQALKAHLLFLKNREYIVGDSGVEIVDEFTGRVLTGRRYSDGLHQAIEAKEGVRVANENKTMATITFQNLFRMFDKISGMTGTADTEAKEFHKIYNLDVVVVPTNRLLARIDEDDTIYYTEEFKFNAITDEVYKTYKKGQPVLVGTVSIEKSEILSAMFKNRGIKHEVLNAKNHSREAFIIAEAGAKHAVTIATNMAGRGTDIKLGGNIEHRVRKKIGTNVSLEEFQEAVKNERENYLKDYNEVKSLGGLYVIGSERHESRRIDNQLRGRSGRQGDPGRSRFYVSLEDDLMRLFAGDNLRSLMGKLGMATGEPITHSLLTKSLINAQKRVEDRNFEIRKHLLEYDDVITKQRDFIYAQRNSILEDTAIKDRILVALEEYLSFLLEGTKSSTVSNVFLNEVNSIFAYMLESLGSIENISSLDLKAKLMQIAKANLDEKENLIGRDLFNGFLRYEYLKNIDFKFQEHLANLDSLREAVYLRSYANKNPITEYKEEGFSIFSELIKDIKVSTIRRVLQLKLDSNSSDFKSTKKSRNVKPIHKELSGIVINENKSASNVQVVRSSPKIGRNEPCYCGSGKKYKNCHGKS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: ARGP_ECOUT
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPESRMMRKVTDALLDYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: MNMA_YERPB
Sequence: MSDNSQKKVIVGMSGGVDSSVSAYLLQQQGYQVAGLFMKNWEEDDDEEYCSAATDLADAQAVCDKLGMELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRQDVDGKSRLLRGLDGNKDQSYFLYTLSHEQIAQSLFPVGELEKPEVRRIAEQLDLVTAKKKDSTGICFIGERKFRDFLGRYLPAQPGPIMTVDGQLVGKHQGLMYHTLGQRKGLGIGGTKEGGDDPWYVVDKDLDSNTLLVAQGHEHPRLMSVGLVAQQLHWVDRQPVTAPFRCVVKTRYRQQDIPCTVTPLDDERVDVRFDDPVAAVTPGQSAVFYQGEICLGGGIIEQRYPLTNPA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BDS3_ANEVI
Sequence: MNKALFLCLVVLCAAVVFAAEDLQKAKHAPFKRAAPCFCPGKPDRGDLWIFRGTCPGGYGYTSNCYKWPNICCYPH
What is the function of this protein?
Blocks Kv3 voltage-gated potassium channels.  Reduces blood pressure.
What are the official names of this protein?
Kappa-actitoxin-Avd4c, Kappa-AITX-Avd4c, Antihypertensive protein BDS-3, Blood depressing substance 3, BDS-3.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: EIF3F_MACFA
Sequence: MATPVVSASGPPATPAPAPVAAPASASASVPAPTPAPAAAAVPAAAPAASSDPAAAAATTAAPGQTPASAQAPAQTPAPALPGPALPGPFPGGRVVRLHPVILASIVDSYERRNEGAARVIGTLLGTVDKHSVEVTNCFSVPHNESEDEVAVDMEFAKNMYELHKKVSPNELILGWYATGHDITEHSVLIHEYYSREAPNPIHLTVDTSLQNGRMSIKAYVSTLMGVPGRTMGVMFTPLTVKYAYYDTERIGVDLIMKTCFSPNRVIGLSSDLQQVGGASARIQDALSTVLQYAEDVLSGKVSADNTVGRFLMSLVNQVPKIVPDDFETMLNSNINDLLMVTYLANLTQSQIALNEKLVNL
What is the function of this protein?
Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f, Deubiquitinating enzyme eIF3f, Eukaryotic translation initiation factor 3 subunit 5, eIF-3-epsilon, eIF3 p47.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDLB_PSESM
Sequence: MTAVARSSLRSTLEPKSFGRVAVLFGGKSAEREVSLNSGNAVLKALLDAGVDAFGIDVGDDFLQRLVSEKIDRAFIVLHGRGGEDGTMQGLLECLEIPYTGSGVLASALAMDKLRTKQVWQSLGPATPLHAVLENENDCICAATELGFPLIVKPAHEGSSIGMAKVNSVDELIAAWKAASTYDSQVLVEQWIQGPEFTVASLRGQVLPPIGLGTPHSFYDYDAKYLASDTQYRIPCGLDDAQEQQLKQLAARACDAIGIAGWARTDVMQDAEGKFWLLEVNTVPGMTDHSLVPMAARAAGLNFQQLVLAILADSVQARG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase B, D-Ala-D-Ala ligase B, D-alanylalanine synthetase B.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5632_BACAN
Sequence: MGNEFRVCDDCQATNVKTLIPKLKKVDSCATIEVGCQSYCGPGRKKSFAFVNNRPVAAPTEDELIVKIEAKLNK
What are the official names of this protein?
UPF0741 protein BA_5632/GBAA_5632/BAS5234.
What is the protein family that this protein belongs to?
Belongs to the UPF0741 family.
Protein: FABH_PORGI
Sequence: MNKINAAITAVGAYLPEDVITNDDLEKMVDTNDEWIMTRVGIKERRILRDKNKGASYLAIRAAQDLFERHGIDPKSIDGLILATNSSDYHFPSTASIVAHEIGCGDIFSFDMQAACPTFIYALEVGANFIRSGRYSKILVIATEKMTAFTDYTDRATCPLFGDGAGCVLLEATEEEVGVMDAVLHSNGIGKDHLIMKAGGSACPATHETVDNRWHYVYQEGQVVFKHAVVDMCNSCVEIMERNNLSHDDITWVVPHQANLRIIDAVARRMGVPYEKVMVNIERYGNTSSATIPICLWEWEHKLKKGDVLVMTSFGAGFTWGAVYVKWAYDGSTVR
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_CORGB
Sequence: MYCPFCQHDHSKVIDSRVIDAGSAIRRRRECSKCEGRFTTIEKAVLLVVKRNGVTEPFSREKVVTGVRRACQGRDVSDDALKRLAQQVEETVRSNGSSQVRANDIGLAILDPLRELDEVAYLRFASVYKSFDSADDFEKEIRLMRRRGRD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ATPE_ACTSZ
Sequence: MATFNLTVVSAEEKIFEGAVKSIQATGSEGELGILAGHIPLLTGIKPGIVKITREDNSEEVLYVSGGFLEVQPNIVTVLADVAIRGIELDQERILNAKRKAEDNIVAKHADVDHNLLVAKLSKELAKLRAYELTEKLVKNKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEU3_CORJK
Sequence: MKLAVIAGDGIGTEVTAEALKVLHALRDDVETTDYDLGARRYLRNGELLTDEDLDSLREHDAILLGAIGDPRTVPAGVLERGLLLPLRFKLDHAVNLRPSKLYPGSSSPLANPGDIDFVVVREGTEGLYCGNGGTLRAGTDYEVASEVSQNTYYGVERVVRDAFERAQSRRKKLTWVHKTNVLVNAGSLWQRAIETVGQEYPEVQVDYNHIDAATIYMVTKPQEYDVIVTDNLFGDILTDLAGAVTGGIGLAASGNIDPSRKNPSMFEPVHGSAPDIAGQGIADPCAAILSVALMLRHLGDDANAERIEAAVLAEAGSRDGGPVKTAEVGDRVVANLK
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOX14_MOUSE
Sequence: MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAPEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATSALPYASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM
What is the function of this protein?
Acts as a negative regulator of transcription.
What are the official names of this protein?
Transcription factor SOX-14.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBFA_BLOPB
Sequence: MYFQHSYRTQRIANEIHKKVSIILQHKIDDIRIGIPTISGVQVSKDLKNANIFVTFINKEGPEEIDTAVMILQRASRFIRFLLANTMCIRVAPILFFKYDSSLIEGAKVCSLISTTEKL
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMEL1_RAT
Sequence: MGKSESSVGMMERADNCGRRRLGFVECGLLVLLTLLLMGAIVTLGVFYSIGKQLPLLNSLLHVSRHERTVVKRVLRDSSQKSDICTTPSCVIAAARILQNMDQSKKPCDNFYQYACGGWLRHHVIPETNSRYSVFDILRDELEVILKGVLEDSSVQHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLNVLDMIGGWPVAMDKWNETMGPKWELERQLAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYIDQPTLGMPSREYYFKEDSHRVREAYLQFMTSVATMLRRDLNLPGETDLVQEEMAQVLHLETHLANATVPQEKRHDVTALYHRMGLEELQERFGLKGFNWTLFIQNVLSSVQVELLPNEEVVVYGIPYLENLEEIIDVFPAQTLQNYLVWRLVLDRIGSLSQRFKEARVDYRKALYGTTMEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKSIVSELIEKIRSVFVDNLDELNWMDEESKKKAQEKALNIREQIGYPDYILEDNNRHLDEEYSSLTFSEDLYFENGLQNLKNNAQRSLKKLREKVDQNLWIIGAAVVNAFYSPNRNLIVFPAGILQPPFFSKDQPQALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMLDWWSNFSARHFRQQSQCMIYQYSNFSWELADNQNVNGFSTLGENIADNGGVRQAYKAYLQWLAEGGRDQRLPGLNLTYAQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLNAQVLGSLQNLPGFSEAFHCPRGSPMHPMNRCRIW
What is the function of this protein?
Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development.  Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues.  Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity).
What are the official names of this protein?
Membrane metallo-endopeptidase-like 1, NEP2(m), Neprilysin II, NEPII, Neprilysin-2, NEP2, NL2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Secreted. Note=A secreted form produced by proteolytic cleavage also exists.
Protein: ISPD_CUTAK
Sequence: MPTMVDEHTPPVVAVVVAAGLGTRFGGPVPKQVTSLTGKAVVAVAVESLAAGGCDEAVVVVKEGMHNHLQLALAASPIPVHFVTGGNTRQESVRNGLRFIAQHHRLSDATTVLIHDAVRPLVPAYVVENVIAAVENGAVAVTPVVDVVDTIRQVDGDTSSVVDRSTLRAVQTPQGFKRDIITECHEQLSIEGGSVTDDISCCERYGHHATFVEGSRMSLKITEPVDLDVAEVFAKAAAGAGRHSGRRIGRMLHAVKPSTVARKLGRGSRR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: UCK2A_DANRE
Sequence: MAGDSDSKLDNHAENEHVDWQPFLIGVAGGTASGKSSVCGKIMELLGQNKIDHHQRQVAILSQDSFYRVLTPEQKAKALKGQFNFDHPDAFDNELIVKTLCEIMEGRTVQIPVYDFVTHSRKEETVTVYPADVVLFEGILMFYSQEIRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQVLNQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDFLNGGLTKRLNGCLNGHTPRKRHPSESSSRPH
What is the function of this protein?
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate.  Does not phosphorylate deoxyribonucleosides or purine ribonucleosides.  Can use ATP or GTP as a phosphate donor.
What are the official names of this protein?
Uridine-cytidine kinase 2-A, UCK 2-A, Cytidine monophosphokinase 2-A, Uridine monophosphokinase 2-A.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
Protein: RL13_BORBR
Sequence: MKTFVAKPHEVKRDWFVIDAKGKVLGRVASEVAHRLRGKHKPEFTPHVDTGDYIVIINAADIVVTGNKAQDKKYFRHTTYPGGIRETNFEKMQQRFPGRAIQKAVKGMLPKGPLGYAMIKKLKVYAGAEHPHTAQQPKPLEF
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ARGC_ACIF2
Sequence: MIRAGIVGGTGYTGVELLRLLLPHPEVELVAITSRAEAGQRVDEHFPNLRGHCNLSYTAPDPAILGTLDVVFFATPHGVAMDSAPKLLAEGVRIIDLGADFRLPDAEVFAQWYGMAHRAPEVLGEACYGLPEYYRTKISEARLIANPGCYPTAVILGLAPLLAEGLLQEDTLIADCKSGVSGAGRSAKVGLILPETADSVSAYGVGGHRHRPEIEAVLSDISGTPLELQFTPHLMPMIRGIHATLYGRLAQPMSDAALQDLFATRYASEPFVDVLPFGSHPATRSVRGANMCLIAVHQPRPGQVVVLSVIDNLVKGAAGQAIQNMNRLFSLAEDAGLMQIALLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.