PharMolix/UniProtQA huggingface dataset:
Protein: SRC1_YEAST
Sequence: MNSDLEYLEDGFDPNSMKVATLRRILVENNVDFPSNARKNALVGLFDEKVKPQIPQLRKMYLNVRPSDEGIVKMDRPSSSPSIASPRRSRRARREKSASPMAKQFKKNRILDDVSNDDDDDDDDDDDNDKKDDPLIVPSGTDTDEVDDEEDDVITSSSNKSDTNDFQQNSDTRKKRKDPDSDDWSESNSKENKIDNKHLNLLSSDSEIEQDYQKAKKRKTSDLNQEHGNGSAILGKLSVKTPIKNTNRKPVSMDNFNDSLTSSGTENDPFVPNIRHNPKELGTANGTGHSTPLSKLKVSASFADKLPQKEVPSTILVPEVEQQEPSQSERTPSLFSSEGSGSESEAPLLPEITTPGPHQPMGNTSNNVVEMIDTDSSNLVSDEDEVLVPTRIETPQLPTEKDVEKCEARVQELQEEVNEQLEHENGSEFDVKQGSGKVGNRHKFKRALKFLSKSLLALFLFCIFIVIPLLFGLWYREQRLLIGYCGHEVPSHRVSGNSFEFIQKLDNLLQDYRPKCIPCPPNGICYPYLKLKCKPDYKLAPSRLDFLEIIPAQGKCVKDDKKQQLVSEVVEKSLEFLRAKNAQISCGDGKDDIESGMTEDALYQIFNEARAPWIRDDEFEDLWIQVIKDLTEEPEILWRQLSPTDNNIGGNSNNIIKTNDVPRQKRHLPEKFISKTRNFRSTSKKYIGMKCRFEREIYQTYKKFQRPIWLMFLLIVISKVIEIKLKNYYRKKARIEELVTQTMEKLKFQKIKSMSDPKENAYLSIVQLRDIFLSDIVDLKYKNQLWSEVVKYLEHNNSNIKSNLTEIRGEIMKCWEWIGPMELNEPKDSAENKI
What is the function of this protein?
Plays a role in sister chromatid separation.
What are the official names of this protein?
Inner nuclear membrane protein SRC1, Helix-extension-helix domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein. Note=Targeting to the inner nuclear membrane requires the SRP1 and KAP95 karyopherins and the Ran cycle.
Protein: RS2_RICRO
Sequence: MSKIPSVNIKALLDAGVHFGHKTSRWNPKMASYIYGKRDDVHIIDLRQSVALMNVALNAIYETVKKDGKILFVSTKIQASDIIAEYAEKCGQYYVNHRWLGGMLTNWKTIAGSIEKLNKLDKTLENEEALMGYTKKEILDMSRKKDKLLLSLAGIRNLNSKPDLLVVIDTNKEHIAINEAVKLNVPIVAVVDTNSNPDNVDYPIPGNDDSIRSIRLYCSLFADAALQGLEESMKASGVDMGAMQEHTDKGLTSKNVSKLKQAKKFSKTKNIDEETNTEFEQVLNDADENKNSDNA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NR4A2_PONAB
Sequence: MPCVQAQYGSSPQGASPASQGYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHWLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
What is the function of this protein?
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development.  It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 4 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mostly nuclear; oxidative stress promotes cytoplasmic localization.
Protein: CPLX2_MOUSE
Sequence: MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYLPGPLQDMFKK
What is the function of this protein?
Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons.  Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles (PubMed:11163241, PubMed:23345244).  Also involved in mast cell exocytosis (PubMed:11163241).  Although not essential for development, seems critical for the acquisition of higher cognitive functions in the adult brain (PubMed:12915444).
What are the official names of this protein?
Complexin-2, 921-L, Complexin II, CPX II, Synaphin-1.
What is the protein family that this protein belongs to?
Belongs to the complexin/synaphin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Presynapse. Nucleus. Perikaryon. Note=Translocated from the perikaryon to the presynaptic terminals during maturation of neuronal cells. In mast cells, cytosol and nucleus. Becomes enriched near plasma membrane following stimulation.
Protein: GPI10_TRYB2
Sequence: MPWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVFFPAVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFRMGATLDELLAKRELELAEEMRQSKTKGFSYFREVFVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFTRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDVIATCYTVPGYSYMHRKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEYVLWRYDGKHSFNMGDLEESRKASELQSVVMPKSAPHPDAMVMTRAVAKEIEEPFLKRHGYRLYRTFLHSPLTLAPYEDIYIQMWVKVTK
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 3, GPI mannosyltransferase III, GPI-MT-III, Glycosylphosphatidylinositol-anchor biosynthesis protein 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MIC60_PARBD
Sequence: MLRTSIATSRQLLSSPVCPKASAQWLRSSNAGRANTTTRRYYAIQQEPNGALRSSLSPSAAAVSDVSQRASNSTNTKRPNTSDLNVRSPASPSTGSTLKPETVLVAPVSPLRQGQSSPGSAAPAPEPAAAPPPSPPPPPPAPKTGRLRKFLLYLFLTTGLAYAGGVWYSLRSDNFYDFFTEYAPYGENAVIYLEERDFRNRFPNATKKNNRRAVAPRDEGAQVTIPGGSGLSWKVAEEQQEGSDISKKGPHMSAVDNNKATKDTKTVEKTKGGVTSKSPAQKEEAVKTKPAPEGVKTQPAKVAETPREPAIPAITTIDHLVLNTEDEPVVQDLVKVFNDIITVISADAPSSFSGPVAKAKEELEKIGKRILALKSDAQASAQKEINDAHASFDKSAANLIRHIDEMRAEDATKFREEFEAERERIAQSYQEKINTELQRAHEVAEQRLRNELVEQAIELNRKFLSDVKNLVEHERESRLSKLAELVSSVAELERLTAGWSNVIDINLKTQQLQVAVDAVRTTLENSNVPRPFIRELAAVKELASNDEVVSAAIDSISPVAYQRGIPSSAHLVDRFRRVATEVRKASLLPENAGITSHAASFVLNKVMLKKHGSPAGNDVESTLTRAENFLEEGNLDEAAREMNSLKGWAKLLSKDWLADVRRVLEVKQALEVIETEARLRCLQVE
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: P5CR1_MOUSE
Sequence: MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDQATVSALRKIGVNLTPHNKETVRHSDVLFLAVKPHIIPFILDEIGANIEDRHIVVSCAAGVTINSIEKKLTAFQPAPKVIRCMTNTPVVVREGVTVYATGTHAQVEDGRLVEQLMGSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLDSEQHPSQLKDNVCSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQTMADQETISPAAIKKTVLDKVKLDSSAGASLSSDHVKPLP
What is the function of this protein?
Housekeeping enzyme that catalyzes the last step in proline biosynthesis.  Can utilize both NAD and NADP, but has higher affinity for NAD.  Involved in the cellular response to oxidative stress.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase 1, mitochondrial, P5C reductase 1, P5CR 1.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MURQ_YERPA
Sequence: MSLGALISESRNPATMELDKLSTLAMLTCINDEDRKVPDAIRLVLPAVAQAVDLAADALKQGGRLIYLGAGTSGRLGVLDASECPPTFGVPHGMVIGLIAGGPGALLKAVEGAEDDIALGMRDLQDLQLTATDMVVGLAASGRTPYVIGALRYARELGCPTAAISCNPDSPIAQEAQVAISPVVGPEALTGSTRMKSGTAQKLVLNMLSTGAMVKLGKVYQNLMVDVKATNVKLVDRACRIVVEATGVSRAEAEHALRQTDFEVKPAILMLLKGVSAEQARQDLRQHHGYLRAAL
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: RL2_MAGSA
Sequence: MALKTFKPTTPGRRQLVLVDRSELWKGKPEKSLTEGLRSKGGRNNTGRVTVRWRGGGHKRRYRIIDFKRNKFDVAATVERLEYDPNRTAFIALVSYADGEKAYIIAPQRLAVGDQVIASEKADIKPGNAMPLKNIPVGTIVHNVELKVGKGGQLARSAGTYVQLVGKDQGYAQLRLASGELRMVRGECMATIGAVSNPDQQNVSLGKAGRAVWMGRRPSVRGVAMNPIDHPHGGGEGRTSGGRHPVTPWGKPTKGKKTRSNKKTDRLIMRRRQTQ
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y1577_METJA
Sequence: MREEKEIIIVCLLIFIVGVVGIFLTTSFNGMKYTSIYIKDYEANLYIGKNLTLEEIYSYEVLEGRKYRMLYRDWKAPLVYNGSLNTPYVKVLNLSTSSKDMVGYVVDYKGDIFVFSDEDWIKRNIEEIVDKYYIRNEVGFYNPLYIRNPGIYTTSYKFVIYPPIETDNVFYHINLKLADEHLPYKNVKINVIDENNSILDLFVYPSTFKVYKTYFGYTIEGSSPKNDPIEVEMLLKPNSVNGFTRYVYNVEGKTISAYKKYTFVSNIVMTLKYLLMAIILLFPLIAYIIYLKFGKEKFYVVPEYLSYVPNKNRKPWIVNLIFAGDAGFFDKEGFYATLLDLHNRGYIKIMNGGKIEILKTDLENLDVYESDVMKFLMKYSKNNVFDPEYIKSLAQKYKSSKDKLKKLKDELDKIMEYPRYSSKVVNAFLETRGKKIIIALLVISILLAVFLYFIPKYSQTFNEVFYLSIVFVVQNIILALTPTSLFGRWKANYYKEKLEWDAFKNFLSNLAMIKKYSPEDISIWKDWLIYGTALGVGDKVVEAMKSLNLSELVADYVIIHSNYDSMKTSVDSVYSSTTGSGGGFGAGGGFGGGGGGAR
What are the official names of this protein?
Uncharacterized protein MJ1577.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPO12_METMA
Sequence: MGYKCTRCKQKVEIDYEYTGIRCPYCGHRILVKERPTTIKRIKAE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo12, DNA-directed RNA polymerase subunit P.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC63_MOUSE
Sequence: MKKSIYRSLKTQQHPLLLRRPLPPKLPKVPLLKKKVRIVHTVKAREPKEETYGKFDPDESAFVKMDQNVSQSQRPTSTQTICLDYDHKALERVVNIFPHQHRVRRFHWKVPKSTAGSMFIPRCLSASSRIFKNTLSQMKKRAKKSSKKEVKEDGYLTKKTFNTLVLSKEFSKPSPTSYSRFIASKFKPLGTQFHPAPKISGYSQELPLLRDVKRAALSPVPSTSSVIPEPQWSERTHPSAAPSKVVLNTGSLPPARSLPTPVLPRKPLRQAMIENAAAAAAAAAAAAAAAAAAATTTTTTTAATTTAAVSGKTEAHKPPETVQRTTRTIGPDAHVLRGEGFKAVAATRSETVLALTTLAIINCQIYGRNALNLKGFFLANCPDLTPVAFQLVYLNLSFNDLNQFPIEILYLQNLQVLKLRNNPIKEIPSEIHLLTYLRIFSIAFNYITKLPDGLFCLNYLEELDVSYNEIENISNEIQKLRSLEKLIVDGNPITSFPPGILKLNLIKLQIENTFTCSQFWLESSWNDPQQLTQICSLFLVKNKLLDYIPDAVRKSLKSTSECDWCHGPKFGEGFRIIRSCDIFGVSHVPIMFHVCSSTCYRDIRETSFVLEGFPSRRIALHMDWVKESKVSNVSFYL
What are the official names of this protein?
Leucine-rich repeat-containing protein 63.
Protein: RS21_ECOSM
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: Y1786_STAAR
Sequence: MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEINKIRKAAELADKCIEIGVSYLKESVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSQEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
What are the official names of this protein?
Uncharacterized peptidase SAR1786.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: VATF_RAT
Sequence: MAGRGKLIAVIGDEDTVTGFLLGGIGELNKNRHPNFLVVEKDTTINEIEDTFRQFLNRDDIGIILINQYIAEMVRHALDAHQRSIPAVLEIPSKEHPYDAAKDSILRRAKGMFTAEDLR
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32165585).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32165585).
What are the official names of this protein?
V-type proton ATPase subunit F, V-ATPase subunit F, V-ATPase 14 kDa subunit, Vacuolar proton pump subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Protein: BIOB_DESDA
Sequence: MTELYTAANPAEALKLVSLPEDELFVGATQLRRATFDNRITLCAIINARSGNCGMDCRFCSQSKHNHTPIETFSLLPDDELRGRILALGTQPVARIGVVTSGGALSGEEFDRLLGVLRSLPEYVLKRVCASLGKLSAVQLAQLMDIGLDRYHHNLETSRRYYPSICTTQTWDQRKATVERVFGAGMTACTGGLFGLGESWRDRIDFAFALKSLGVTHVPMNFLHPHPETPLAGQPPLTAGEALRIVAVFRHILPTATLRICGGRPLVLGARQKEIFAAGANALMTGDYLTTQGRGLVDDLAMIDSLGLEVDCDQSC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: KAD_SHEPC
Sequence: MRIILLGAPGAGKGTQAQFIMEQYGIPQISTGDMLRAAVKAGTPLGLEAKKVMDAGQLVSDDLIIGLVKERIAQDDCAKGFLLDGFPRTIPQADAMAANGISIDHVIEIDVPDEEIVKRMSGRRVHPGSGRVYHVVFNPPKVEGKDDVTGEDLAIRPDDEEATVRKRLAIYHEQTKPLVEYYGKVAAAGQTKYNKFDGTQSVAAVSEQLASVLK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_EHRCJ
Sequence: MTDQGIVKINASLRENVGTGPARAVRRNGGIPAVVYGKNRDSLSVFLSDREFLSKHRSAALSTHLIELEIGDKKEYVLMRDVQKHPVTDRIQHVDFQFIDYGTEIKIEVPLIFTNEQKCIGVKRGGVLNILHRTLSIKCLPNAILQNIEIDLSDLTAGHSIHVSDLNLPPEINVVMKEHNPAIVTISSTSMEKEGEGSQEPTAAPSSEN
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RNY_CHLPM
Sequence: MGIVINLFLLVPASIVFFAAGFFLGRFFLERLGTTKVLEAEERAVQIVQEAQKEANEYKDLKVTEVNQEWKKKRREFDQEVVIKNNKFNQMQKQVQQREGQLKKQAQDNRDMERRLQDQRKENEQVQESVTLRAAELERIISEQNERLESISGLQSEDARQMLIDNMISKAREEATETIHQIHEEAEQEAERLAEKTLLTAIQRITFEQATENALSVVHIQTDELKGRIIGREGRNIKAFENATGVDIIVDDTPEVVILSCFDPLRRELAKLTLQKLLSEGVIHPVAIEKAYEDASKEIADVIMSAGEDALSSLQLPDMPAEVVKTVGKMKFHTVYGQNLLQHSREVAMLAGVMATELKLDARLAKRAGLLHDIGLVLPATDEPHAISGRNFLKRFNESGVVLNAIAAHHGEVEKESPIAELVDAANVISLSRPGARGAMTADGNVKRLESLEEIAKGFPGVIKTYALQAGREIRVIVEGDNVSDSQADVLAHDIAHKIESEAQYPGQIKVSIVREKRSVAYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NRSF_CAUVN
Sequence: MRTDDLIDALAADAGRGTEPAPPRRLALVAGLGGVAALLLVLGWLQARPDLGQAILGPMFWVKAIYTGLLGLAGYLAVERLSRPGGSGRRGWIIGAVVFGACAVAGIYQAITSPDVQAALKLLHGYSWRSCSPRILVLGLPMLALGLWALRGMAPTRPGLAGFAMGLFSGGVVATLYGLHCPEHTFTFLALWYSLGVLALGLIGGWAGRWLLRW
What is the function of this protein?
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-F (SigF), which responds to chromate and cadmium.  Overexpression leads to loss of response to dichromate.  ECF sigma factors are held in an inactive form by a cognate anti-sigma factor (Probable).
What are the official names of this protein?
Anti-sigma-F factor NrsF, Negative regulator of sigma F, Regulator of SigF, Sigma-F anti-sigma factor NrsF.
What is the protein family that this protein belongs to?
Belongs to the NrsF anti-sigma-F factor family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDM34_ARTOC
Sequence: MAFNFNWSPLMADAGFYTRAQELLTAALNKSPKPPIIVGDITVTELNLGSIPPELEILEIGDLADDRFRGIFKMSYSGDAYLTLKTCVQANSLNTYMVTRPKFTSPCPLAADHGLTIPLQITLSDIKLSGFVVLVFSKQKGITLVFRNDPLESLKVSSTFDSIPFVRDYLQRTIEGQLRLLFMDELPAIIHRLSLRLWVPELRGQDTEVKADEEAGPGQDPLLSPPQDPVDASGNVLSVAQIASLSLDSGVEMHSLFSQRNLVRLATLTDSQRTLSLFTPTIHDVVFRALTGAMEQSESHGGLISPASPPLSRTHSHVASLHSLQESSMSKSSLGSPLSGCGLTMGAGRHPRTRPSRKHKRRVVDLRKPQKLDDTSSTCTDSEYTVSTDASTVFSSSARVGEKPDDPITPPVSPDATIKVKDRSRVPAMQGLGPSVTNKAGQSTPSAEAEKITLSNGEPSYIPHQNTPTIEAHEKGDDNTISLNGVPPSMLSFVAVSQDRSILEQAWMMKLANEISRRIQEGKGPGSVGSNYCGRRDPSPPPAYGQ
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: FMT_SALHS
Sequence: MSDSLRIIFAGTPDFAARHLDALLTSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQHLVADLHADVMVVVAYGLILPKAVLDMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPITAEDTSGSLYNKLAELGPQGLITTLKQLADGTATPEAQNEALVTHAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVATGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CYB_ISOMA
Sequence: MTNLRKTHPLMKIINDAFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLFKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIVTAMVIVHLLFLHETGSNNPSGLNPDSDKIPFHPYYTIKDALGLLLMVLLLLLLAMFSPDMLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLMSILVLLIIPLLHTSKQRSLMFRPISQILFWLLAADLFTLTWIGGQPVEQPFIIIGQVASILYFLLIIALMPLAGLLENYMLKPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KATG_MYCIT
Sequence: MSSDTSSSRPPQPDSGTASKSESENPAIPSPKPKAHAPLTNRDWWPDQVDVSSLHPHSPLSNPLGDDFDYAAEFAKLDVEALKADMISLMTTSQDWWPADYGHYGGLFIRMSWHAAGTYRIHDGRGGAGQGMQRFAPLNSWPDNASLDKARRLLWPIKKKYGNKISWADLITYAGNVALESMGFKTFGFGFGREDVWEPEEILWGEEEEWLGTDKRYSGERELAQPYGATTMGLIYVNPEGPEGKPDPIAAAIDIRETFGRMAMNDEETAALIVGGHSFGKTHGAGDADLVGPEPEAAPIEQQGLGWKSSYGTGSGKDAITSGLEVVWTPTPTKWDNSFLETLYGYEWELTKSPAGAWQFTAKDGAGAGTIPDPFGGAGRAPTMLVTDISLRESPIYADITRRWLDHPEELADAFAKAWYKLLHRDMGPISRYLGPWVAEPQLWQDPVPAVDHELVDDNDVAALKKKVLDSGLSIPQLVKTAWSAAASYRNTDKRGGANGGRLRLQPQRSWEVNEPSELDKVLPVLEKIQQDFNASASGGKKISLADLIVLAGSAAVEKAAKDAGYEISVHFAPGRTDASQESTDVESFAVLEPRADGFRNYIRPGEKAPLEQLLIERAYLLGVTGPEMTVLVGGLRALGANHGSSKHGVFTDRPGALTNDFFVNLLDMGTEWKASETAENVYEGRDRASGALKWTATANDLVFGSNSVLRGLVEVYAQDDAHGKFVEDFVAAWVKVMNSDRFDLK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.  May play a role in the intracellular survival of mycobacteria.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase, Protein Mi85.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PSEH_HELPY
Sequence: MKKNYSYKNIQAIDFTNLNDGEKLLVLEFRNHPNTALWMYSTFISLKTHLQFIEDLKNSPNHRYFLFKEEGVYLGVGSITKINFFHKHGYLGIYKNPFLKNGGETILKALEFIAFEEFQLHSLHLEVMENNFKAIAFYEKNHYELEGRLKGFISKDKEFIDVLLYYKDKKGYNDQSLLKL
What is the function of this protein?
Catalyzes the third step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin.  Mediates N-4 acetylation of UDP-4-amino-4,6-dideoxy-beta-L-AltNAc to form UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose.
What are the official names of this protein?
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase, Pseudaminic acid biosynthesis protein H.
Protein: DEOC_BREBN
Sequence: MNMNKYIDHTLLKPDATQEMIDKLCQEAREHDFMSVCVNPYWVKRSAELLAGSDVKVCTVIGFPLGASTIESKAAETRDAIANGATEVDMVLNVGALKSGDLETVKKDIAAVKQAAGDILLKVILETCLLTEEEKVVACKLSVEAGADYVKTSTGFSTGGATVEDIALMRKTVGPNVGVKASGGVRDGETAVAMIEAGASRIGTSSGVSIVTGAKTTGSGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.