PharMolix/UniProtQA huggingface dataset:
Protein: TGT_STRPS
Sequence: MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSIGGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIRLTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RS21_PSET1
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGILSEVRRREHYEKPTAERKRKKAAAVKRHMKKLSRDNARRVKLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: FRE_PHOLU
Sequence: MTTLSCKVTSVEAITDTVYRVRLLPDSPFLFRAGQYLMVVMDERDKRPFSMASTPSEKEFIELHIGASELNLYAMAVMDRILDQKVINIDIPHGKAWFRKSSANPLLLIAGGTGFSYTRSILLTALEEQPKRHISMYWGGRESQHLYDLAELRLLTERYPNLKVIPVVEQSDNGWCGRTGTVLKAVLEDFGSLANYDIYIAGRFEMAKIARERFCSERDASADSMYGDAFEFI
What is the function of this protein?
Involved in bioluminescence.  It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction.  Preferably uses riboflavin as an electron acceptor when NADPH is used as an electron donor.
What are the official names of this protein?
NAD(P)H-flavin reductase, NAD(P)H:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein oxidoreductase family.
Protein: GATA_HELAH
Sequence: MITLKQALSLSQDELETLKNGIDANVRASDLNAYIKAPSLNGASAKGVPILIKDNISVKGWEITCSSKILEGYVAPYHASVIENLHQNSMAGFGLSNMDEFAMGSTTESSCYGITKNPRDKNRVPGGSSGGSAAAVAGGLAVAALGSDTGGSIRQPASYCGCVGLKPTYGRVSRYGLIAYCSSFDQIGPITQNVEDASILFDAISGHDSKDSTSANLKPTQTFKNLNRERRFKIAVLRDHIKDASNEVQLAYENTLKALKEIGHEIVEKKILDSHYQISIYYIISMAEASSNLARFDGVRYGRRAQNIKDLKELYLKSRSEGFGDEVKRRIMLGNFVLSSGYYDAYYLKAQQMRLMIKEQYNKIFEEVDLIFTPVAPTTAPLFNYHASPLEMYLSDIYTIGANLSGLPALSLPVAKDPLGLPIGMQFIAKAFDEQSLLDVSYALEQELKLKLD
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: IF3_STAAS
Sequence: MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTAQ1_CAEEL
Sequence: MISAEEALYQSCYCEENVYKLIEKIDDKNGIFAIIISNDCKMIPLWKQKAAKSINGHVLWDYHVIAIEKEKNGSKVYDLDSTLEWSCDFLEYWEKTMNLAEMAQRDTKFRRKFRVIPGENYISLLSSDRSHMLSKNGVYLKPPPEWPLINSHKPSNLMELIRMSEQIENTTVMDEPELFQLFSK
What is the function of this protein?
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation.  Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule.  Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.
What are the official names of this protein?
Protein N-terminal glutamine amidohydrolase, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase.
What is the protein family that this protein belongs to?
Belongs to the NTAQ1 family.
Protein: Y3943_DICDI
Sequence: MVFLLFLSFVLSSIFLVPLVYMLNKVFLFNRNRVVNYDSIRKLALTRME
What are the official names of this protein?
Putative uncharacterized protein DDB_G0291508.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMK_SODGM
Sequence: MKLAILSRDGTLFSCRRLREAAQARGHKVDVIDPLSCYMNINSAAPSIHYRGRRLKHYDAVIPRIGPLTTFYGTAVLRQFEMLGSYALNESAAITRARDKLHSLQLLARQGIDLPITGFADSPDDTGDLITMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLKAQFLVQEFVAEAGGRDVRCLVIGDKVVAVIERHAKEGDFRSNLHRGGSARAVTISAAERAVAIHAAAALGLNVAGVDILRAKRGPLVMEVNASPGLEGIEAASDMDIATLMITFIEARLADRSSR
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: YHHS_SALEP
Sequence: MPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDAMGFSAFWAGLIISLQYFATLLSRPHAGRYADVLGPKKIVVFGLCGCFLSGLGYLLADIASAWPMISLLLLGLGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVLCYAWGGLQGLALTVMGVALLAVLLALPRPSVKANKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSVAFVGTRLLFPNGINRLGGLNVAMICFGVEIIGLLLVGTAAMPWMAKIGVLLTGMGFSLVFPALGVVAVKAVPPQNQGAALATYTVFMDMSLGVTGPLAGLVMTWAGVPVIYLAAAGLVAMALLLTWRLKKRPPSALPEAASSS
What are the official names of this protein?
Uncharacterized MFS-type transporter YhhS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YhhS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPP_PSINU
Sequence: MPIGVPKVPFRLPGEEDAGWVDVYNRLYRERLLFLGQQVDDEIANQLIGIMMYLNGEDENRDMYSYINSPGGAVLPGISVYDAMQFVVPDVHTICMGLAASMGSFILTGGEITKRIALPHARVMIHQPASSYYDGQAGECIMEAEEILKLRDCITRVYAQRTEKPLWVISEDMERDIFMSAKEARAYGIVDLIALEND
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ACTB_CAVPO
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells.  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.  Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: Y1609_ENTFA
Sequence: MVVDLKMLAMIFIINFAYITLNTIRFMLTMKGYRVIAPLVSMAEITIYVLGLSMVLNRLDNPLNLLVYALGYAVGISVGIKIEDYLALGYIMVSVILPSTTEQFHLPETLREHGYGVTQSVAYGREGERMVLEILSPRKNERTLYKLINQLEPRAFIISYEPKFISGGFWTKKVRKRNDAISH
What are the official names of this protein?
UPF0316 protein EF_1609.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BLCAB_XENLA
Sequence: MYCLQWLLPVLLIPKPLNPALWFSHSVFMGFYLLSFLLERKPCTICALVFLGALFLICYSCWGNCFLYHCSASELPEAAYDPAVVGT
What are the official names of this protein?
Bladder cancer-associated protein B.
What is the protein family that this protein belongs to?
Belongs to the BLCAP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GCH1_ECOBW
Sequence: MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: Y4387_SERP5
Sequence: MNKQPEDWLDDVPENIDEEDDEIIWVSKSEIKRDAEALKDLGVELVELGKNALERIPLDEDLRAAIDLAQKIKKEGRRRQLQLIGKMLRARDVEPIQTALDKLKNRHNQQVSLFHKLEALRDRLVEEGDDAIPPILALYPEADRQQLRSLVRNAQKEKAANKPPKAYRQIFQYLRDLAETAE
What are the official names of this protein?
UPF0307 protein Spro_4387.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: RS21_PHOV8
Sequence: MIVVPVKEGENIEKALKKFKRKFEKTGVVKELRARQQFDKPSVLNRLKRERAIYVQKLQQVEE
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: UXAB_ESCF3
Sequence: MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGAQDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVTKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPREELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFALAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDGVIGTQELVAIVLAEKDHWEQDLTQVPGLVELVANDLDAILEKGMREAVRPLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: MATK_CHAOB
Sequence: MDEFQRNSNKHRSWQQFFLYPLFFREDLYAIAHYHHLDRSGSSEPTEILVSNFLSFLTVKRSIRRIRKQNNSISLLGNSDSNKLIEYNKNSSFQLILEGFTIXLEVXXXXRSKHFIKXMDGWNSXRSIHCIXXFMEAKLPHSNYISDLRVPYSIHPEILVRIFRRWIRDVPSLHLLRSILHEWKNSFNRENLQKALITQRENTRFSLFLWNSYVYECESFLIPLIKRILNSQSLLYGSFPDRTHFEKKIKDIVIFPPHKISTKKIWLLKDSFIHYVRYGERSLIALKGTHLQVKKCRYHLFHFWQYYFHLWFQPYRICSLELSKTSFSFLGFFMHVKMRPLVVRAKMLDDLFITDLITNELNSTAPIRSILFSLAKEKFCDISGWPISKLSWTSLSDDDILDRFDRIWINLFHYYSGSINQDGLYHIKYILLLSCAKTLACKHKSTIRVIREQLGSELFTKSFSKEREFISSSSSKTRLQRERIWNLEIXQINPLANFWQKMQNKQIKN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL25_CAMHC
Sequence: MLEGIVRESIGRKSSKALRRDGYLIANIYAKGFKNINAAFKVNDFIKVVKAKTTLPFEVKIADKTYKVVVQDYQKHPVTNALKHVDLRIVLDNEISHYLVPVKIVGVAKGLRNKGILVQSKRRLTVKCAGKDLPNEFVLDVSDLDVNDSLLVRDIKLPDNVSIVENNSVAVVGVSTAQ
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: NU6C_ACOAM
Sequence: MDLPGPIHDVLLVFLGSGLILGGLGVVLLTNPIYSAFSLGLVLVCISLFYILSNSYFVAAAQLLIYVGAVNVLIIFAVMFMNGSDYSNDFYLWTVGDGVTSLVCTSILFSLITTILDTSWYGIIWNTGSNQIVEQDLTSNVQQIGIHLSTDFYLPFELVSIILLVALIGAITMARQY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CCM1_CANAW
Sequence: MIRLILWNNVQSLVFKRCLFVPSNSLTNKRKRRIPPSKPRSSNRKDGDIEPYRMTDQNQTPNTGSIARLPAEVKKELKDLRSFTKVIAQHLKPEQENDSLTSAEKPDTSQLPPIDIEEATDDIFGEISGTKKLSANAVPPPPPPPPPGLDIPDEIKERLGLLSELLVPAKTSNNKLPEKQVENNWKLLLSQLDQAGGLSGLSKRSVSKFFSKIPPKNLKNLIPMIENMYNKAEMSIPHPIYYMFVRSLTLGDKISDSQMQLINKYFQEISKQTDLKIDHYETMILAYVKNNHMEKIDGILAQMKKKNIEISKMIYTSIVRGYIFYQKDHQRALDTFDSMKFLSQKTQPDEKVYTDVIVSCVMHREIERALDLYYELKDKGMNVNQNLLSTLAKGCSRSKQFKTQAWNFLFQVYDHGWVPNLQTYEHMLYIAARDGDVELTRVLFYKMLQTNSVTIRAFRYLILSYSKYVPPHKRKEKHLILLNHKGQLFRQNILQDVDFSKPVHGFPFLPSSHIPDSKFVLAESSAIWAHTVMNNPSFLRQQTLVASYVSIALELGDFTEFKDRFDSASYLNTDGIPKVREIEIIEPRQDEPTEKATTTEEQITSSEPDTNSLIRSPILNQLQQNINDNQFKAPRDSYLYNLAIKAAGKFKDYSFAQQILHERGQFRKSNSFKLLSPKQQNQDDFQFAGYLVECWTNMNLLEDAYAVVLSSVDRFPWSWRELGVLNNAAMKLGSLELAEAVRKVAQVTQVKHHGKIKRQDFKTYVMKRGY
What is the function of this protein?
RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts.  Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity).
What are the official names of this protein?
Mitochondrial group I intron splicing factor CCM1.
What is the protein family that this protein belongs to?
Belongs to the CCM1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS17_PARXL
Sequence: MNDSVKTSLKRTLVGKVVSNKMDKTVTVLVEHRVKHPIYGKYVVRSKKYHAHDDANTYNEGDLVEIQETRPISKTKAWVVARLVEAARVI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: YBFA_ECOLI
Sequence: MELYREYPAWLIFLRRTYAVAAGVLALPFMLFWKDRARFYSYLHRVWSKTSDKPVWMDQAEKATGDFY
What are the official names of this protein?
Uncharacterized protein YbfA.
Protein: Y1313_RHIME
Sequence: MDISRAEQRILHHLAQGGRIEITREGKAIAEIRCFTRDGWVYPGVDLELFRKLKRKRAIKSSAGKPYRITERGLHLVRSELNNR
What are the official names of this protein?
UPF0386 protein R01313.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: MURQ_BACAC
Sequence: MLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEEEGRLIYIGAGTSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGASTASISCNKNAEISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTNEKLVERSKRIIVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKQAKGFVKKAL
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: LECB_STYJP
Sequence: ISITFFLLLLNKVNSAEILSFSFPKFVSNQEDLLLQGDALVSSEGELQLTTVENGVPVWNSTGRALYYAPVHIWDNSTGRVASFATSFSFVVKAPVASKSADGIAFFLAPLNNQIHGAGGGLYGLFNSSSYSSSYQIVAVEFDTHTNAWDPNTRHIGIDVNSVKSTKTVTWGWENGEVANVLITYQAATEMLTVSLTYPSNQTSYILSAAVDLKSILPEWVRVGFTATTGLTTQYVETNDVLSWSFTSTLETSDCGAEDNNVHLASYAFI
What is the function of this protein?
GalNAc-specific lectin.
What are the official names of this protein?
Bark lectin, LECSJABG.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: FTSH_POPEU
Sequence: FLEYLDKDRVRVQLPGLSQELLQKTPGFSGADLANLLNEAAILAGRR
What is the function of this protein?
Seems to act as an ATP-dependent zinc metallopeptidase.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FTSH, chloroplastic.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: MURD_GLOVI
Sequence: MAAVAVVGAGKSGQAAARWLALGGRRVVLWDGRDSEALRVVAGALAPFGVEAVLGREFVPEEPDLSLVVVSPGVRWDHPGLVAARARGVTVTGEVGLAWESLSHRRWLCVTGTNGKTTTTALVGHILKTAGLRAPVCGNIGRPVTDLLLEPEDYDWIVAELSSFQIESAQGIRPEVAVWTTFTPDHLNRHGTLERYAAIKAGLLMQARRAVLNGDDAYLGARRSAWPDAWWTSTQAPAAVSLAGKDICIENRPVLPVSAVRLPGAHNLQNVLMAVAACHLTGVGDAAIASGVASFIGVPHRLEAVGEYRGVRFINDSKATNYDAALVGLTAVPAPSVLIAGGQAKTGESGPWLRAIAERCASVVLIGEAAPLFEKWLRAQDYRAVYTAHTLERAVPMAFEQARAQGAQCVLFSPACASFDQFRNFEERGDRFRALIAALAS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX8A_SAISC
Sequence: MSVLTPLLLRGLTGSARRLPVPRAQVHSMPPEQKLGVLELAIGFTSCLVTFLLPAGWILSHLDSYKKRG
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8A, mitochondrial, Cytochrome c oxidase polypeptide VIII-liver/heart, Cytochrome c oxidase subunit 8-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: MALA_MALAU
Sequence: MAPTPKYTFTERAAAGNLSDAEILNSNNPTGSELPDESDVVVGGAGIHGLIYALHASKYKPNNLKISVIEKNTRPGYKIGESTLPIFYTWCKLHGISAAYLLRLFGLKDGLCFYFLDRENQGQYTDFCSVGAPGLVLASLQIERPMSELLFTILAQRNGVNVYHGREVDFKSTVVQGGGQGNKIAVSRGKYDSTPKTIDSALFVDATGRFRQFCSKKAPRHRFDGWNCNAFWGYFTAPKDESKIPFDLYEGDHTNHLCFPEGWVWVIRLPSWEGSLIANLMDMVTYILECADAGVPGDELPSSEELARMFGLKFQWVTSIGFAVRNDVKYPEDLSAYGTREAEQKFNYFVQKYELLQQFMSNFELIENLYGPGTTWFIRKTLAYQSPVVSGPGWLAIGDACGFTNPLYSPGINVGMSTSTWAAQLSHRIVEIGKSAPADAAESSIRKLLVPYDDYCKSLVPALEQMNRFNYVCYRDTRLGPQVACLWQFFAGIERYLSDVNIETFAHYAIKWVWGAMVPEYQQVAQKCIEHIETVPLDERLPDAMVDELLAFSNRIKSAAVAADDFSLRWDAILRSFDRSLNFVEGKTSRDIYTRQCSGCGAWLQLRPDWKKCHSCGLLGTEPQTAVTFDPPLTAEEEALLYAAWNTAPKYDPSKELKLPTPTRPAA
What is the function of this protein?
Flavin-dependent halogenase; part of the gene cluster that mediates the biosynthesis of malbrancheamide, a dichlorinated fungal indole alkaloid that belongs to a family of natural products containing a characteristic bicyclo[2. 2. 2]diazaoctane core (PubMed:23213353, PubMed:31548667, PubMed:28777910).  The first step of malbrancheamide biosynthesis involves coupling of L-proline and L-tryptophan by malG, a bimodular NRPS, to produce L-Pro-L-Trp aldehyde through reductive offloading (PubMed:23213353, PubMed:31548667).  This compound undergoes spontaneous cyclization and dehydration to give a dienamine which is reverse prenylated at C-2 by malE (PubMed:31548667).  The other prenyltransferase present in the cluster, malB, displays modest activity, suggesting that may be a redundant gene in the pathway (PubMed:31548667).  Subsequently, a [4+2] Diels-Alder cyclo-addition catalyzed by the bifunctional enzyme malC forms the characteristic bicyclo[2. 2. 2]diazaoctane ring of premalbrancheamid (PubMed:31548667).  Finally, the flavin-dependent halogenase malA catalyzes the iterative dichlorination of the indole ring of premalbrancheamide to yield C-9 monochlorinated malbrancheamide B, C-8 monochlorinated isomalbrancheamide B, and dichlorinated malbrancheamide (PubMed:31548667, PubMed:28777910).  MalA is also able to brominate premalbrancheamide at C-9 to yield malbrancheamide C, and, to a lesser extend, at C-8 to yield isomalbrancheamide C (PubMed:28777910).  Finally, malA can brominate C-9 monochlorinated malbrancheamide B at C-8 to yield malbrancheamide D, or C-8 monochlorinated isomalbrancheamide B at C-9 to produce isomalbrancheamide D (PubMed:28777910).
What are the official names of this protein?
Flavin-dependent halogenase malA, Malbrancheamide biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the flavin-dependent halogenase family.
Protein: Y4NG_SINFN
Sequence: MVKNFLGSSVTSGSAGAEHGKTLQIPTLRWVRQSKTSIMALVICLGRIVKTALVTGGSGYFGELLSKQLLRQGTYVRVFDLNPPGFSHPNLEFLKGTILDRNAVRQALSGIDKVFHNVAQVPLAKEKDLFWSVNCGGTQIIVDESVATGIEKFVYTSSSAVFGAPKSNPVTEETEPNPAEDYGRAKLAGEIICKEAMQRDGLDVAIVRPRTVLGYGRQGVVQILFDWVERGLDIPVLGGGNNKYQFVHSDDLASACIAASNVKGFATYNIGAAEFGTMRELLQVVIKHAETGSRIKSIPMGPTALAANLASALGLSPLGPYHSLMYGRAMYFDISKAQKELGYAPRYSNSQMMIETYNWYQANRASLGKGGGSRHKAPVKQQLLALLPYALRLIPG
What is the function of this protein?
Putative nucleotide sugar epimerase/dehydrogenase.
What are the official names of this protein?
Uncharacterized protein y4nG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.