PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_SHIFL
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YBEY_PROMH
Sequence: MSEVILDLQVATENTQGLPSEAQFITWLEAVLPQFQPISEVTIRIVDEAESHELNLTYRGKDRPTNVLSFPFEAPPEVELPLLGDLIICRQVVEKEADEQNKTVEEHWAHMVIHGCLHLLGYDHIEDDEAEEMEGLETEILQKLGYEDPYLIEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNRA_DICDI
Sequence: MEEDNIVDSKEIENNVEDKKEETPSSSPSPSSSLQQQQEEGGVVKQAVSNLVSSSITLHDDAKLIQVTGKDEPFHFISVPMSVEFLNLEDVFIMQSDAYIFVWCSEQANIKKKAKAVQMAQKLKVEIGCQRAVQVLEIGEEHPTFLFCLGVPKGTKLNVTKEKNDIFQVDEDDEEQVLEPEFFLFKIFTGTDGKPSIKPMEEDEGINQEMLESSACFILDCEHEMYIWLGKGVKKSTKDTLIPVAKKIWTQYDRPEYYGKLKLQPIITWVFDGAESCLFKSKFSKWVEKAQPLQTSYLSLSSKKKEALNFDVSSMHQDKEVPVINIGAASDYSNGKLLVWCSGGGSGNKWNKVEEDDFGIFYSNKSYVCHFIYKPENKNSIRSVIFFWEGLYSNQRNYIGYKFGLYKEIQKKMEGLKSDDPVEYRISQNKEPQEFINLFGTELLVLNEELALKPMIFQVRANRGTQLFPDPDSCNAKLLNSLDSFVFLFPNKYIIVWHGKVSTEHQRELAADLFTFLPPEYEAGVKEFDQGKESDNFWKIIGGNSNDIVINTFINENKEEKEKEEEEKEEEEEEEEEEEEEEEEEKDNNKTTTIIKHLRPKKIKLFLCTDNSGIFKADQINPFSQVDLNSQECVLLDVYHKVFLWKGSKSTDQKLNDTQDLAKQYIETANDQRPSDCSVELVEQYNESPLFKSYFHSWKVTPPKVFIDPIISYKQKLAERLQKEKEDLEKLKQQQEQEQEQQQKENNKIVEEVKEEVKEEDVKEEVKEEEVKEEEVKEEEVKEVAKEETKEEIKEEVNDEATEVKEVNQVEEEVKEEEVKEEVKVEVKEEEVKGEAKEEEVKEEEVKEEEVKEEVKEVKEEVKEEVKQDKEEEVNEEIKEETKEEETKEDDNKEDEKVNEENETVNEENEVGIIVSPPSEKVDEANSSSTISSPENEGSVSVKDKRKSNEPITPSVVSSSGDLLFAYEPYHGPPIHSSNSPKQGRKGGRKSHGKNQPQHKKNHSVDQSPLSSPIIPNKSLNLDIDNQSFDLNSINNNNSVEVLDGASSPLSFSSSSINSNSTHNTPSKKNKNKNKKKHNRSSSLTHA
What is the function of this protein?
Involved in phototaxis.  Required for coupling photodetection to the locomotory machinery of slugs.  May be essential in the natural environment for the propagation of spores.
What are the official names of this protein?
Gelsolin-related protein of 125 kDa, GRP125.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle.
Protein: KDKA_HAEIG
Sequence: MYQFQQDNQYFIFNFDRTFDQATEFFQAEFWQKQERVIGSAKGRGTTYFLQTEDWFGVNCALRHYYRGGLWGKLNKDRYRFSDLETTRSFAEFHLLQRLYEAGFPVPKPIAARIQKGKLGICYQADILTEKIENAQDLTALLQTQTLPKETWTQIGRLIRKLHDLQICHTDLNAHNILLQQIEQEQKCWLLDFDKCGEKSGDFWKVQNLNRLKRSFEKEIRRMNIQFTEQNWADLTAAYHQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PGTB1_YEAST
Sequence: MCQATNGPSRVVTKKHRKFFERHLQLLPSSHQGHDVNRMAIIFYSISGLSIFDVNVSAKYGDHLGWMRKHYIKTVLDDTENTVISGFVGSLVMNIPHATTINLPNTLFALLSMIMLRDYEYFETILDKRSLARFVSKCQRPDRGSFVSCLDYKTNCGSSVDSDDLRFCYIAVAILYICGCRSKEDFDEYIDTEKLLGYIMSQQCYNGAFGAHNEPHSGYTSCALSTLALLSSLEKLSDKFKEDTITWLLHRQVSSHGCMKFESELNASYDQSDDGGFQGRENKFADTCYAFWCLNSLHLLTKDWKMLCQTELVTNYLLDRTQKTLTGGFSKNDEEDADLYHSCLGSAALALIEGKFNGELCIPQEIFNDFSKRCCF
What is the function of this protein?
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl diphosphate to proteins having the C-terminal sequence Cys-Ile-Ile-Leu or Cys-Val-Leu-Leu.  Acts, among other substrates, on Rho1 and Rho2 and CDC42 proteins.  Participates in a RAS-like C-terminal modification of proteins involved in nuclear division and bud growth.  It is involved in bud positioning and cell polarity (PubMed:2034682, PubMed:1400380).  The beta subunit is responsible for isoprenoid and peptide-binding (PubMed:9109664, PubMed:10491163).
What are the official names of this protein?
Geranylgeranyl transferase type-1 subunit beta, GGTase-I-beta, Cell division cycle protein 43, Geranylgeranyl transferase type I subunit beta, RAS proteins geranylgeranyltransferase subunit beta, Type I protein geranyl-geranyltransferase subunit beta, PGGTase I beta.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PT1_STAAW
Sequence: MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMDGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRN_CAVPO
Sequence: MWTLVGWTILVAGLVAGIRCPDDQVCPVACCPDSGGASYSCCDPGVDLRTTALSGYLGRPCQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQRPDIHLLGAVQCPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNKAKTLLTKLPSWTVWDVECDQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTCEQGLLQVPWAQKTPAQPSRPSQPSPPGPPGPPSPPGPLRSEISCDEVVSCAPGNICCRLASGEWGCCPSSEGYLCMAGERCQVGDRLAPEKMAAHLMSLSQTTDVGCDQHASCPVGQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSCEKAADGAHLAAPLAVGSTGGVMDVACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKSLLHWDSLPRPAAPRPRL
What is the function of this protein?
Stabilizes CTSD through interaction with CTSD leading to maintain its aspartic-type peptidase activity.
What are the official names of this protein?
Progranulin, PGRN, Acrogranin, Proepithelin, PEPI.
What is the protein family that this protein belongs to?
Belongs to the granulin family.
What are the subcellular locations of this protein?
Secreted. Lysosome. Note=Endocytosed by SORT1 and delivred to lysosomes. Targeted to lysosome by PSAP via M6PR and LRP1, in both biosynthetic and endocytic pathways (By similarity). Co-localized with GBA in the intracellular trafficking compartments until to lysosome (By similarity).
Protein: CSTP1_BOVIN
Sequence: MLSPERLALPDYEYLAQRHVLTYVEDAVCQLLENKEDISQYGIARFFTEYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLESVAAIYQDLLSGKNPNTVIVPTSSSGQHRHRPSTGEAGTPEGVEASLFYQCLENLCDRHKYSCPPPALVKEVLSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLVLRWRPHRSSRQHRAKEPGAFGYQRRDKLEALQTVPPASAPTPCLYQWEPIE
What is the function of this protein?
Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly.  Regulates the assembly and stability of the TPGC and thereby modulates polyglutamylation of the microtubule, which antagonizes MAP4 binding.
What are the official names of this protein?
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1.
What is the protein family that this protein belongs to?
Belongs to the CSTPP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Protein: RECO_STRPD
Sequence: MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSKMSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAIADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDLPLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKLRQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RL7_CLOP1
Sequence: MTKEQIIEAIKEMSVLELNELVKACEEEFGVSAAAPVAVVGGAAAGAAAEEKSEFDVVLTNAGANKIKVIKAVRELTGLGLKEAKEIVDGAPKTLKEAVAKEEAEDMKAKLAEVGAEVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TAL_RUEPO
Sequence: MKFFVDTAEIDAIAELNDLGMVDGVTTNPSLIKKSGRDIIEVTREICAMVDGPVSAEVTATDAETMIAEGRKLVEIAGNIAVKVPLTWDGLKACKVLSDDGHMVNVTLCFSANQALLAAKAGATFISPFIGRLDDINLDGMELIEDIRTIYDNYGFETQILAASIRSVNHILDSARIGADVITAPPAVIKAMVNHPLTDKGLDAFLADIKAADIKIL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPE_AMOLO
Sequence: MFTLKKSLLLLFFLGTINLSLCEQERNAEEERRDEPDERNAEVEKRFFPIVGKLLFGLSGLLGK
What is the function of this protein?
Antimicrobial peptide with activity against Gram-positive and Gram-negative bacteria and against fungi (PubMed:19843479).  Has been tested against S. aureus (MIC=1. 25 ug/mL), B. pumilus (MIC=5. 0 ug/mL), B. cereus (MIC=15. 0 ug/mL), E. coli (MIC=1. 25 ug/mL), B. dysenteriae (MIC=5. 0 ug/mL), A. cacoaceticus (MIC=15. 0 ug/mL), P. aeruginosa (MIC=5. 0 ug/mL) and C. albicans (MIC=1. 25 ug/mL) (PubMed:19843479).  Also shows a weak hemolytic activity (PubMed:19843479).
What are the official names of this protein?
Temporin-ALe, Amolopin-2f.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL23_PSEA6
Sequence: MINEERLLKVVLAPHVSEKATLAAEVNNTVVFKVLKDANKEEIKAAVEKLFEVEVNSVRTVNVKGKTKRHGASFGKRKDWKKAYVVLKEGQDIDFAGSEG
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: FB323_ARATH
Sequence: MTTMISNLPRVLIEEIFFRVPLKSLRAVRLTCKSWNTLSKSRSFRKLYISKRATREEESMMIAMMNFDLYSMRVVVDDDVDPSKAFKKKRNKKSIAFKRQPIFLDEQVKISQVFHCEGLLLCFLKEDDTRVVVWNPYCGQTRWIQLRYSHRPHKDRFIYALGYKDKESRGSFQLLRFVDYFLGAPKNQYFWYEIYDFNSDSWTTLDVTPHWCIYCCDRGVSLNGNTYWCAKERKAEDDIVDHIISFDFTNERFGPLLPLPSKVMEHEYEIVTLSYVKEEKLAALFQHYEADWNEFDIWITTKIDAEVVSWSMFLRMDTGPRIEVPHICEGFFIDEEKKVAMGFEEDFDRKTFIIIGEAGYVRKLDIKAHVDRKCRPTVCSYVPSLVQIKKPARGKRKRQSSLEKRLFDQNMLRLEAFKKLGGYF
What are the official names of this protein?
F-box protein At2g38590.
Protein: RSMI_BACSU
Sequence: MLRRQMSFNGKSDMGILYLVPTPIGNLEDMTFRAIDTLKSVDAIAAEDTRQTKKLCHVYEIETPLVSYHEHNKESSGHKIIEWLKSGKNIALVSDAGLPTISDPGAEIVKDFTDIGGYVVPLPGANAALTALIASGIVPQPFFFYGFLNRQKKEKKKELEALKKRQETIIFYEAPHRLKETLSAMAEILGDREIAVTRELTKKYEEFIRGTISEVIGWANEDQIRGEFCLVVEGSNNEEVDEEEQWWETLTAKEHVEHYISKGATSKEAIKKAAVDRNVPKREVYDAYHIKQ
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHG24_RAT
Sequence: MEENCDSTENPHSQGRQNATKCGWLRKQGGFVKTWHTRWFVLKGDQLHYFKDEDETKPLGTIFLPGNKVIEHPCNEESPGKFLFEVVPGGERDRMTANHESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSKEEEAGVKELTKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSAQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDRLFPKDTEPQSKPQEGPNSNNNDGHKKVTMGQLQNKENNNTKESPVRRCSWDKPESPQRSSMDNGSPTALSGSKTNSPRNSIHKLDVSRSPPLTVKKNPAFNKGSGIVTNGSFSSSNAEGVEKTQTTPNGSLQARRTSSLKSSGTKMGTHSVQNGTVRMGILNTDTLGNSLNGRSMSWLPNGYVTLRDNKQKEPAGESGQHNRLSTYDNVHQQFSLMNLDDKHSVDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFYGGNFEDPVLDGPPQDDLSHPGDYENKSDRRSVGGRSSRATSSSDNSETFVGNTSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMLNLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGDLTVEPRRSERGNTIWIQ
What is the function of this protein?
Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization.  Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state.  Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity.  Able to suppress RAC1 and CDC42 activity in vitro.  Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia.  Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 24, Down-regulated in nephrectomized rat kidney #2, Rho-type GTPase-activating protein 24.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction, focal adhesion. Cell projection. Note=Localizes to actin stress fibers. In migrating cells, localizes to membrane lamellae and protusions (By similarity).
Protein: PVK3_BLADU
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, BlaDu-PVK-3, PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RTCA_ECO45
Sequence: MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITGIRAGRAKPGLLRQHLTAVKAAAEICRATVEGAELGSQRLVFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGVHQQTTLLRHGFYPAGGGVVATEVSPVASFNSLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGTGEFTVAHPSCHLLTNIAVVERFLPVRFGLIETDGVTRVSIE
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGIN_HUMAN
Sequence: MDRGLPGPATPAVTPQPPARPQDDEEAAAPHAAAGPDGQLGTVEQRLEPAKRAAHNIHKRLQACLQGQSGADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLERDVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSSQGLGGSPGSHSHTTMANKVETLKEEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEIQADYHRRSLSSLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRSTGSLAAAVETASGRQALVVGKPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRCGMTTVLTLTGVSRLEEAQAYLAAGQHDLVPHYYVESIADLTEGLED
What is the function of this protein?
GTPase activating protein (GAP) which specifically converts GTP-bound RAC1 and CDC42 in their inactive GDP-bound form.  The GAP activity is enhanced by the non-covalent binding of K-29 and K-48 polyubiquitin chains.
What are the official names of this protein?
Bargin, Chimeric SH3BP1-PDXP protein.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm, cytosol. Note=Localization to membranes is increased by binding of poly-ubiquitin chains (PubMed:23223568). Enriched in tangle aggregates in cells of Alzheimer's disease brain (PubMed:23223568).
Protein: RLMN_MAGSA
Sequence: MIQRHLGQPRLIQNGGDAGGVKAVAQKQTQRRLDQIFPAGRGSHANLHSIPTGYACIIAALTENSQRRHCFAARPSLCVAVMDDSKTNLIGLSRDQLIAEMASIGEKPFRAKQLWHWMYNRGETDFAKMTSISKSMHGALAERYVVRRPGVTKELISADTTRKWLLKFDDGHEAETVYIPDADEERGAVCISTQVGCTLTCRFCHTGTQLLVRNLSAAEIVGQFMVARDSYGEWPTPDDGGRQLSNIVVMGMGEPLYNFENVATALEIAMDGEGIGISKRRITLSTSGVVPMMKECGERLGVNLAVSLHAVTDEIRDRIMPINKKYPLKELMQACREYPGASNARRITFEYIMLKGINDSAADARALLKLVKGLPAKFNLIPFNPWPGSEFDTPDIKTTKAFSDILQDAGYSAPIRMPRGRDILAACGQLRSESQRERASLAKARAAAGIADEHHG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_PHOLL
Sequence: MRVSDFTFELPDEMIAHYPQPQRSGCRLLSLDGETGALTHGIFTDVLDKLNAGDLLVFNNTRVIPARIFGRKATGGKLEVLVERVLDDKRVLAHVRASKAPKEGTELLLGDNESLKATMLARHDTLFEIRFDDERDVLSILDDIGHMPLPPYINRPDEEADRELYQTVYSERPGAVAAPTAGLHFDEPLLEALRKKGVEMVFVTLHVGAGTFQPVRVETIEDHIMHAEYAEVPQDVVDAVLACKARGNKVVAVGTTSVRSLESAAKACQDELIAPFFNDTQIFIYPGFEYQVVDALITNFHLPESTLIMLVSAFAGYKNTMNAYQEAVAEKYRFFSYGDAMFIRRNPFACKEKIS
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_RICRS
Sequence: MTFPNINPVIFSIGPLAISWYSLSYVIGILLGWFYANKIIEKFKPQITKKNLEDFITYAVIGIIVGGRLGFVLLYNPSRYFSNPIDILKTYEGGMSFHGGALGGIIAAYLFCRKYKINFLSLTDIIAPVVPIGLFLGRIANFINGELYGRITNASFGMIFPNSDLMPRHPSQLYEAFFEGLVLFSILAYATFKHKTLKKCGLNSGIFFTFYGLFRITIEIFREPDIQIGFILDSLTMGQILSVPMLLLGSYLICQSNPK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_SMIGI
Sequence: MINLRKTHPLMKIINHSFIDLPAPSNISAWWNFGSLLGICLVIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLAEWIWGGFAVDKATLTRFFAFHFILPFIIMALVIVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGLMFLLLVLLSLALFSPDSLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPFLHTANQRSMMFRPVSQTLFWILTANLITLTWIGGQPVEQPFIIIGQLASILYFTLLLVLMPLAGMFENYMLEAQR
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IRC19_VANPO
Sequence: MDSVPSIRILTKNAVITSKYTLLKNHSKYYMPNHNLKDIDEDTVVKMYYRRFIRLRPLISRTRMVKETYTSYIRYKFKIENYQLKRKLVTGIEEQRPLIPTLQKSLEFIIKSVSFIPETKTIKFKIARDNTICRQVLKNLLTVEYQKENFIEKRSKGSELYQLLRVDFNHLVNSNNNLKFTSQLKVFNDFDMCLILMNETIGTRL
What is the function of this protein?
Involved in sporulation and maintenance of the mitochondrial DNA.  Is probably involved in a pathway contributing to genomic integrity (By similarity).
What are the official names of this protein?
Increased recombination centers protein 19.
What is the protein family that this protein belongs to?
Belongs to the IRC19 family.
Protein: PURA1_ORYSJ
Sequence: MSLSTVNHAAAAAAAAAGPGKSFSAAAPAAPSVRLPRTRAPAAAAVSAAAVGADRAADRVSALSQVSGVLGSQWGDEGKGKLVDVLAPRFDIVARCQGGANAGHTIYNSEGKKFALHLVPSGILHEGTLCVVGNGAVIHVPGFFNEIDGLESNGVNCNGRILVSDRAHLLFDLHQAVDGLREAELANSFIGTTKRGIGPCYSSKVTRNGLRVCDLRHMDTFGDKLDVLFKDATSRFEGFEYSKSMLREEVERYKRFAERLEPFIADTVHLLNESIQQKKKILVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPRCIGDLIGVVKAYTTRVGSGPFPTELFGEEGDLLRKSGMEFGTTTGRPRRCGWLDIVALKYCCEINGFSSLNLTKLDVLSGLPEVKLGVSYNQPDGQKLQSFPGDLDTLEQVQVKYEVLPGWQSDISSVRSYSELPLAAQRYVERIEELVGVPVHYIGVGPGRDALIYK
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase 1, chloroplastic, AMPSase 1, AdSS 1, IMP--aspartate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.