PharMolix/UniProtQA huggingface dataset:
Protein: MYF6_MOUSE
Sequence: MMMDLFETGSYFFYLDGENVTLQPLEVAEGSPLYPGSDGTLSPCQDQMPQEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQEKMQELGVDPYSYKPKQEILEGADFLRTCSPQWPSVSDHSRGLVITAKEGGANVDASASSSLQRLSSIVDSISSEERKLPSVEEVVEK
What is the function of this protein?
Involved in muscle differentiation (myogenic factor).  Induces fibroblasts to differentiate into myoblasts.  Probable sequence specific DNA-binding protein.
What are the official names of this protein?
Myogenic factor 6, Myf-6, Herculin, Muscle-specific regulatory factor 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y194_EHRCR
Sequence: MFDHRILEILVCPLTKDKLQYNKDTNELISEKAKLAFPIRDGIPIMLIDEARKLEE
What are the official names of this protein?
UPF0434 protein ECH_0194.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PRR19_MOUSE
Sequence: MDPRGPVPQPFQQLQKPGRIRRRKTRRERNKALVSSHRPLARQDPPISSRDPCVILQDPVASAAPKLVVITQGRLSREHRGLFNHEVKSLDVARLLNRGALESHTPQLPTKPSCSPVGVQEPDLQSKGKENKVPGGSGPGPPNSPDLPVLGQLLEELQYQLIVPQAFPRRNLVQESRDTIIRTLQGCHGCVPDLALVLRGCQLPLPEAKPRVPERQRMASSCMEVPEHAPREGKQRTQQATKGCDFAIPHTCNSTTPAHRGSQVQPPGHQLPFLSSASSPSGAAWGPPTAFDMLKSIWLIATPPPPPPQPWDVRPPQPLPQPPSPLLPRTSALDWSPNPPAPLPSLSWVVTQSSPEAWSFPPMRLY
What is the function of this protein?
Promotes meiotic crossing over formation through its interaction with CNTD1 by participating in the crossover differentiation step of crossover-specific recombination intermediates.
What are the official names of this protein?
Proline-rich protein 19.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Co-localized at crossover sites with CNTD1 (PubMed:32555348). Localizes on synapsed chromosome only in mid/late pachytene spermatocytes (PubMed:32555348).
Protein: RCSF2_PSEAI
Sequence: MSHSISPIGHVRSCFKEKFAIPRQPQLAPAATGVLELLPPFDTGDAVEGLEQVSHVWLIFLFHQALEDKPRLKVRPPRLGGNQSMGVFATRATHRPNGLGQSVVKLEKVEPGRLWLSGIDLLDGTPVIDIKPYVPYADIVPDAHNAIADAPPSSIAVHWSDEALRQAHEHGLRLCQPVRELVGNASPRTRARPTRSRRPSAAMACACGTSTCTGTTPPMARSACWTCNAPPTETSLSPQD
What are the official names of this protein?
Putative S-adenosylmethionine-dependent methyltransferase RcsF.
What is the protein family that this protein belongs to?
Belongs to the tRNA methyltransferase O family.
Protein: OBG_PSEPF
Sequence: MKFVDEVSIRVKAGDGGNGCMSFRREKFIENGGPNGGDGGDGGSIFMMADENLNTLVDYRYTRHFDAERGSNGGSTDCTGKKGEDLILRVPVGTTVIDSATQEVIGDLTKAGQKLMVVQGGWHGLGNTRFKSSTNRAPRQTTPGKPGEQRDLKLEMKVLADVGLLGLPNAGKSTFIRSVSAAKPKVADYPFTTLVPNLGVVSVDRWKSFVIADIPGLIEGASDGAGLGIRFLKHLARTRLLLHLVDMAPLDESSAPDAAEVIVNELIKFSPSLAERDRWLVLNKCDQILEEEHEARVKEIVDRLEWTGPVYVISAIAKEGTERLTRDIMRYLEDRADRLANDPAYKEELADLDQRIEDEARAQLQALDDKRALRRSGVKSVHDIGDDDWDEEDVDDEDGPEIIYVRD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MU105_SCHPO
Sequence: MSKCLQQLKRQLQHFGIDGCSLADGDIDYFFTVTGIDRGWGCGWRNIQMLISWLQYTNPNWFKRNFSSGNYEINSLQSLLLSAWMKGIDAEGYAQLGDNLHGKWIGATEVYSLFTGLFVNVALVDFDFRSEASASNALFLYVKKHFESSNDTSNVSPCYLQFQGHSIIIIGFCSSLETLVVLDPDRYQSVQKKFVNIADFNHCYMRKKRSLKFSQFQLVHFKQNIFLNDFSSKLEVRSTRISDF
What is the function of this protein?
Deubiquitinase with endodeubiquitinase activity that preferentially cleaves 'Lys-48'-linked polyubiquitin chains (PubMed:29576528, PubMed:29476094).  Shows only weak activity against 'Lys-63' and 'Lys-11'-linked chains (PubMed:29476094).  Has a role in meiosis (PubMed:16303567).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase mug105, Lys-48-selective deubiquitinase mug105, DUB, Meiotically up-regulated gene 105 protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family. ZUFSP subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBAC_HOPLI
Sequence: SLTAKDKALVKAFFGKIAGKADAVGHEALVRMLVVYPQTKTYFAHWPDLSPSSEEVKKHGKTIMAAVKEAVGKIDDLVGGMAQLSDLHAFKMRVDPSNFKILSHNILVTCAVHFPDDFTPEVHVSFDKFLAALSSTAADKYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin cathodic subunit alpha, Hemoglobin cathodic alpha chain, Hb(Ca) alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YBEY_STAAR
Sequence: MFTIDFSDHTGLVKDAWYKQIEDLLEFAKKEEHIEDDAELSVTFVDKQEIQEINRTYRDKDKVTDVISFALEEDEPDIDFSGLDIPRVLGDIIICTDVAQEQANNYGHSFERELGFLALHGFLHLLGYDHMTEADEKEMFGRQDTILNAYGLTRD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMA2_STAAS
Sequence: MGIIAGIIKFIKGLIEKFTGK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 2 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: UNG_UREPA
Sequence: MKWKEFIINETKQSYLKNIIKKINNIENHQVVFPLKKQRFRCFDFFDIEQTKVVILGQDPYHTPKIANGLCFSVDLGNNLPGSLINIFKALEYDLQIKRTNPDLSDWAKQGVLLLNTVLTVNAHQPNSHKNFGYEELIKNVFNELRKQKHVVYLLWGKQAMSYINLIDQKQNLILCASHPSPLSAHRGFLTCKHFSKCNDYLIKHLRTPIKW
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_EHRRG
Sequence: MKVIGSLKSAKIRDKDCRVVRRKGRIYVINKKNPRFKARQGY
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PP4R2_RABIT
Sequence: LQEALKDFEKRTGETMIQWSQFKGPPNPNVEYIPFDEMKNVMVVMNGVMFPINGPGTPRPLNRPNLQQNEEKNHHPDE
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).  May regulate the activity of PPP4C at centrosomal microtubule organizing centers.  Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs.  The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA double strand break repair (By similarity).  Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner.  RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 2.
What is the protein family that this protein belongs to?
Belongs to the PPP4R2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=Ionizing radiation induces relocalization to nuclear foci and colocalization with RPA2.
Protein: CO6A1_HUMAN
Sequence: MRAARALLPLLLQACWTAAQDEPETPRAVAFQDCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALHYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENKYLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIATDHTYRRNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKCPDYTCPITFSSPADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQYSGTGQQRPERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGAAKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNEPHIRVLVTGKTAEYDVAYGESHLFRVPSYQALLRGVFHQTVSRKVALG
What is the function of this protein?
Collagen VI acts as a cell-binding protein.
What are the official names of this protein?
Collagen alpha-1(VI) chain.
What is the protein family that this protein belongs to?
Belongs to the type VI collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ENV_RMCFV
Sequence: MACSTFSKPLKDKINPWGPLIILGILIRAGVSVQHDSPHKVFNVTWRVTNLMTGQTANATSLLGTMTDAFPKLYFDLCDLVGDYWDDPEPDIGDGCRTPGGRRRTRLYDFYVCPGHTVPIGCGGPGEGYCGKWGCETTGQAYWKPSSSWDLISLKRGNTPKDQGPCYDSSVSSDIKGATPGGRCNPLVLEFTDAGKKASWDGPKVWGLRLYRSTGTDPVTRFSLTRRVLNIGPRVPIGPNPVIIDQLPPSRPVQIMLPRPPQPPPPGAASIVPETAPPSQQPGTGDRLLNLVDGAYQALNLTSPDKTQECWLCLVAEPPYYEGVAVLGTYSNHTSAPTNCSVASQHKLTLSEVTGQGLCIGTVPKTHQALCNTTLKTNKGSYYLVAPAGTTWACNTGLTPCLSATVLNRTTDYCVLVELWPRVTYHPPSYVYSQFEKSYRHKREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATQQFQQLHAAVQDDLKEVEKSITNLEKSLTSLSEVVLQNRRGLDLLFLKEGGLCAALKEECCFYADHTGLVRDSMAKLRERLTQRQKLFESSQGWFEGLFNRSPWFTTLISTIMGPLIILLLILLFGPCILNRLVQFVKDRISVVQALVLTQQYHQLKPLEYEPQ
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the virion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: PTH_STRPC
Sequence: MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNFKAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKLRLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAISLTLDRVVNAVKFYLQENDFEKTMQKFNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1002L_ASFK5
Sequence: MGNKESKYLEMCSEEAWLNIPNIFKCIFIRKLFYNKWLKYQEKNLEKRLKLLSFYHPKKDFMGIRDMLDMAPGGSYFITDNVTEEFLMLVVKHPEDGSAEFTKLCLKGGCIVIDGFYYDDLHIFITENPNLYKYPLIHYDR
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 100-2L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 100 family.
Protein: GUAA_SYNS3
Sequence: MSSVQSEGQRKPAIVILDFGSQYSELIARRVRETEVFSVVLGYSTSAEELRALAPRGIILSGGPSSVYADEAPLCDPAIWDLGVPVLGVCYGMQLMVQQLGGQVVAATGKAEYGKAPLKVDDPTALLTNVESGSTMWMSHGDSVEALPDGFLRLAHTANTPEAAIANHKRRLYGVQFHPEVVHSTGGMVMIRNFVYHICGCEPDWTTEAFIDEAVANVRDQVGQKRVLLALSGGVDSSTLAFLLKKAIGDQLTCMFIDQGFMRKGEPEFLMEFFDRKFNIHVEYINARERFIKKLDGITDPEEKRKIIGTEFIRVFEEESRRLGPFDYLVQGTLYPDVIESAGTNVDPKTGERVAVKIKSHHNVGGLPKDLRFKLVEPLRKLFKDEVRKVGRTLGLPEEIVSRHPFPGPGLAIRILGEVTEEKLDCLRDADLIVREEVNAAGLYHDIWQAFAVLLPVRSVGVMGDKRTYAWPIVLRCVSSEDGMTADWSRLPYDLMEVISNRIVNEVKGVNRVVMDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: TTC9C_XENTR
Sequence: MAEQTGAVDQCLLQASSFKSQGNKCYTEHRMRQAVSLYHKALLQLRSLDASLYSPLPGVGPTAVKLNSQQAEELKTLQADCYNNLAACLLQSQPPRYQRVYECSLQVLSLQPENVKALYRAGVSSYHLKDYTNAHHYLSQAASRAPKDGNIKRYVQLTDTALSTFREEEKQRYQGMFG
What are the official names of this protein?
Tetratricopeptide repeat protein 9C, TPR repeat protein 9C.
What is the protein family that this protein belongs to?
Belongs to the TTC9 family.
Protein: PGK_STRPG
Sequence: MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEEAINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSEGFLGLDIGPKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAGTIDVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED14_ANOGA
Sequence: MAPQPLEQGGAVTSFIPTGQEMAQRQNLIPLGRLIDFIIQRTYHELTVLAELLPRKTDMDRKIEIYNFSASTRQLFIRLLALVKWANSASKVDKSAKIMGFLDKQSMLFIDTADMLSRVARETLVHARLPNFHIPAAVEILTTGSYSRLPSVIRDRIVPPDPITPAEKRQTLQRLNQVIQHRLVTGSLLPQLRKFRIENGRVTFKVDHEFEVSLTVMGDAPTVPWRLLDIDFLVEDKETGDGKALVHPLQVNYIHQLIQGRIVDCTDALAEVYTCLHYFCQSLQLEVLYTQTLRLIRDRLDDHIHVDEYVVGSRLTVSYWRELTNKDPKSELGYRLTIQTDPNDAAKQLAILHVPSIGNKEADIADRAVRSDLLSMERLLVHTVYVRSLARLNDVKTELQLFLKDVEYNIQGTPAMLTVPVLNPCLRAEHIYITVDTHTGMLRCHVPKHLDCPIMPEMQHALNNDWSKLQHLISELRYWITQRRCEKTLQHLPAATQDRLPLIYSHTHPIARMGPHKVFIQLYRHANVILIVELKEKKTCPNEMTYTFYLVLVKPSSVEEGQSPDVLSGQPPQPSAAGGPAPGSDSANAAMPKMYLRVLSMIEFDTFVATHGPGTYIDDPSPTSTSGTSVKRKVSPLDNALSAIGPPLKQQKTIYPAYFIPELAHVVAMCDEKLPFVTLAKEFSMRKIPHGGLQVEANATSLVLKLLTLPQPKPPQAPPTPQQQQQQQQQQQQPGTSDAKSSGAGASANEPKTVHVPPIDKQVWNALLKRLLSVSVRAQVNKSNQTRLWTMELVFYGSPLPSLHHKEQGMRRAVYLQYEMQPVESVSKVVDQLLSDWSKIVYLYTLVHEFREQYNNEKYNLPSMVAIKSYSYTNLLLAYGPNKDVSVNICWDTEAKEFRLVFTGGNSAINAHSMMRDQLQAHLNHNYSLAQVVHMLHETYQPLSSIAKLPIIPHLAILQSPKIPVLSFCIIPQSPTLLRISFQGVYCLEVRFRGGGLCTIRDGAYSRFDRSHVVEEFTPTQGLKGFLSKYVDETAVFRRRSQSEDDNPPSPVTLEDPSAGAGNNGGGGGGGGGAGGGANTFLSGGTGMRGPQSPRDPGLRFAAPLTPPTSSNPHTPASPHPIGGGGGAGGAGGQGGQGGQGGQQQSHMNNFNMTSPPASHMPHPSPGGGLMPSSPLNAQPSPMAAHSPGPSSLSYMQSHTDGSPFAALSPAASNWPGSPGMPRPSPRPGQSPEHKVQTSHHYTSRVLPARSWAGAIPTTLTYEALDTLCRATPHPQKEVPGPELSPLERFLGSVFMRRQLQRIIHQEESLMAITSNEPGVVVFKADCLQYQVFLNPNHMQSLHLKVDQLPMGPMMDGKPPYQWAAQDLQILEQFFDHRVAAPPYRPAVMTSFTRMLNLPAKVLKDFIQIMRLDLMPELVQGNKWNVQFVLRVPPSATPIVPVGTTTILSHRQKILFFIQITRVPYLPNMEWKDAVTMLLPMVYDMNMNHTTLAERREPMPPQLTSAVSAHLRRFSECSVLLPDECSLFPAVHDLLLTLTLPNEPPAPGQMQMQLGGVMQPGGGPGVPGGPGGPMGGQIGGPTPQVVPQVGSSPSPMMHSPMQQMGGGGPQPGAYGGMVGGPGGGPQSGGPVGGGPGGPN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 14, Mediator complex subunit 14.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 14 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OSMW_SALTY
Sequence: MDTIHYMLDNAGYLASLTFQHLWLVALAVGLAIIIGVPLGVLIVRHKWLATPVLGAATLLLTIPSIALFGLMIPLFSLIGHGIGVLPAVTAVFLYSLLPIVRNTHTALDSLPPGLREAGRGIGMTFWQRLRWVEIPMALPVIFGGIRTAVVMNIGVMAIAAVIGAGGLGLLLLNGISGSDIRMLIAGALMICLLAIVLDWLLHRLQVVLTPKGIR
What is the function of this protein?
Part of the OsmU ABC transporter complex, which is involved in the uptake of osmoprotectants such as choline-O-sulfate and glycine betaine.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Osmoprotectant import permease protein OsmW.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CXQ_CONIM
Sequence: MRLTTMHSVILMLLLVFAFDNVDGDEPGQTARDVDNRNFMSILRSEGKPVHFLRAIKKRDCTGQACTTGDNCPSECVCNEHHFCTGKCCYFLHA
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Im026, Conopeptide im026.
What are the subcellular locations of this protein?
Secreted.
Protein: ACCA_PSEFS
Sequence: MNPNFLDFEQPIADLQAKIEELRLVGNDNSLNIGDEIARLQDKSSTLTEDIFGKLTSWQIARLARHPRRPYTLDYIQHIFTEFDELHGDRHFSDDAAIVGGIARLDDQPVMVIGHQKGREVREKVRRNFGMPRPEGYRKACRLMEMAERFKMPILTFIDTPGAYPGIDAEERNQSEAIAWNLRVMSRLKTPIIATVIGEGGSGGALAIGVCDQLNMLQYSTYAVISPEGCASILWKTAEKAPDAAEAMGITADRLKGLGIVDKVIAEPLGGAHRDPAAAAATIRGELASQLAMLKKLDNEALLARRYERLMSYGL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_SHEON
Sequence: MAISAAQVKELRERTGAGMMDCKKALEETNGDMELAIDNMRKSGAAKAAKKAGNIAADGTILIKNGEGFAVLLEVNCQTDFVAKDANFLGFANAVLDVAAASKVTLEDLKAQFEEARVALVAKIGENINVRRVEYIDGAKLASYRHGERIGVVVTGDADEETLKHLAMHVAASKPEYVNPEDVPADVVAREQALQIEISMNEGKPADIAEKMVVGRMKKFTGEISLTGQAYIMEPKKTVGEFLKEKGAKVTNFIRLEVGEGIEKKEEDFAAEVAAQIAASKKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_ECOUT
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: AMPP1_ARTBC
Sequence: MTIFRPHLRFLFKPHFLYFQSPIGKSSRPFSTSQILRTALDMPPPPVDTTQRLAKLRELMAQNKVDVYSMQFRYTIKAPLIITVVYSFFFFLLLALKLCLRKTAISQSTLLHVTGVETLIRITAAFISSFTGSAGCAIVSMSKAALSTDGRYFSQAAKQLDANWTLLKRGVEGVPTWEEWTAEQAENGKVVGVDPSLITAGENLQYSPLTSVIVVNCSYVIADARKLSQTLKTTGGSLIGIDQNLIDAVWGDERPARPANQITVQPVERAGKSFEEKVEDLRKELAAKKRSAMVISTLDEIAWLFNLRGSDIPYNPVFFSYAIVTPSVAELYVDESKLSPEARKHLEGKVILKPYDSIFQASKVLAESKASASSGSSGKFLLSNKASWSLSLALGGEQNVVEVRSPITDAKAIKNEVELEGFRKCHIRDGAALIEYFAWLENALIKEGAQLDEVDGADKLFEIRKKYDLFVGNSFDTISSTGANGATIHYKPEKSTCAVIDPEAMYLCDSGGQYLDGTTDTTRTLHFGEPTEFQKKAYALVLKGHISIDNAIFPKGTTGYAIDSFARQHLWKEGLDYLHGTGHGVGSFLYAEVPLSANNVLSNEPGYYEDGNFGIRLENLVICKEVQTAHKFGDKPFLGFESITLVPFCQKLLDASLLTEAERKWVNDYHARVWEKTSPFFEKDELTTAWLKRETQPI
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: LSM4_BOVIN
Sequence: MLPLSLLKTAQNHPMLVELKNGETYNGHLVSCDNWMNINLREVICTSRDGDKFWRMPECYIRGSTIKYLRIPDEIIDMVKEEVVAKGRGRGGLQQQKQQKGRGMGGAGRGVFGGRGRGGIPGTGRGQPEKKPGRQAGKQ
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).  The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm4.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRE_BUCA5
Sequence: MDWKKEFIDFSFKKKVLKFGVFQLKSGRISPYFFNSGLLSTGIDIIKIGLFYARSIIDSKNKFDVLFGPAYKGIPIAVATSIALKNHYNLNVPYSFNRKEYKEHGEKGDLIGSTIYKKRVIILDDVITSGTAIHHSIKIIEKQEASISSIFVLLDRKEKGIRKLSTINHFRNQKSYKIISIITIDDLIEYVLEDKKLKEHIPQLIKYREKYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TIG_DESAP
Sequence: MKASAEKIDKNRVELQVEVEPERLDEVLNQAYRKLVRKANIPGFRPGKAPRPVFERFYGKQSLYEEAMEQLIPRAYLEAVADTGIQPVSQPEVDVVQLEEGKPVILKIQVDVKPEVVLGEYKNLKVERQVAEVSDSEVDEELEKLRNRYAKLVTIEEGTVEMGDIITIDYEGTINGEPFAGGSATDRSVEVGKGFVAKDFDAHLVGMSTGETREIPLSIPEDFPNKEVAGKEALITVTVKEIKRKELADLDDEFAKDVSEHDTLEALRAETRKKLENAAEKKIEYVMRNALISEAVAGAEVEVPASMVDARLETMMEEVLRPVIEQGMTKEDFFKLTNQTEESMRADIRPRAEESLKKELVIDRIAEVEGLEATEEEVDAELAKMAEFYRLEADRLREILEQRNDLDSIRTAIKRDKAVDLLVANAEIVGQESTEAEK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.