PharMolix/UniProtQA huggingface dataset:
Protein: G6PI_SHEB2
Sequence: MTLLTQSSTWQALSAHSKNVPHMRELFATDTARFNKMSLSACGLLLDYSKNRATAETLDLLFALASNSQLEAKIKAMFAGEIINTTEKRAVLHTALRSTAEQSIIAEGQDIVPEVQQTLNKMQGFVSSVTSGQWKGYTGKAITDIVSIGIGGSFLGPKIVSQALRPYWNPELKCHFVANVDGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAREWFLAKGGLQSDVAKHFVAVTSNVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRALLSGAHQMDEHFANAPLTENMPVIMGLLSLWYGNFFNAQSNVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGTAVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFIMPLQSHNPIGEHHDQLASNCFGQTQALMQGRTFDEALAELANSALSATEKQLIAKHKVMPGNKPSNTLLMDKLTPSTLGALIALYEHRTFVQGAIWDINSFDQWGVELGKDLGNDVLTRIGASQDCDALDASSNALINLYRQGKI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF2_YEAST
Sequence: MVAFTVDQMRSLMDKVTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIKSTAISLYSEMSDEDVKEIKQKTDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTYADEVLGDVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFGVDKAKMMDRLWGDSFFNPKTKKWTNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQAYRAEQLYEGPADDANCIAIKNCDPKADLMLYVSKMVPTSDKGRFYAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRFVEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMKFSVSPVVQVAVEVKNANDLPKLVEGLKRLSKSDPCVLTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETVESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKARARIMADDYGWDVTDARKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHADAIHRGGGQIIPTMRRATYAGFLLADPKIQEPVFLVEIQCPEQAVGGIYSVLNKKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTSKAGEIVLAARKRHGMKEEVPGWQEYYDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2, Eukaryotic elongation factor 2, eEF2, Ribosomal translocase, Translation elongation factor 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STR5_STRTC
Sequence: MGSDLTHLEGRPPQRWQWRVFVLAALLSATFAFFTHTCSSPLPQRCRPYLPNVFNKHSLQHNEPEVRDALLAVDSFVRQSFHENPEIDGLVAAVVTANGAIYETALGPLKANETRPEDRGAVDRYSIFRLASGSKLFAMLEILILRERGALQLDDPIAKYLPQFAHKHGGWANEDDIDEGPITIRHLASHMSGMTREYPRGNMDHWPHSLEGIGPPPMNGAPFPDTLEETVLGISHYPLNLPTSTYPVYSNAGMALLGQIAVVANAAAERSQGVDVAR
What is the function of this protein?
Beta-lactamase-like protein; part of the gene cluster that mediates the biosynthesis of strobilurin A, an antifungal polyketide that contains a key beta-methoxyacrylate toxophore that targets the complex III of the mitochondrial electron transport chain (PubMed:30258052).  Strobilurin biosynthesis begins with construction of benzoyl CoA by step-wise elimination of ammonia from phenylalanine by the phenylalanine ammonia-lyase str11, oxygenation by str8 and retro-Claisen reaction to form benzoic acid, which is activated to its CoA thiolester benzoyl CoA by the dedicated CoA ligase str10 (PubMed:30258052).  Benzoyl CoA forms the starter unit for the highly reducing polyketide synthase stpks1 that produces the polyketide prestrobilutin A (PubMed:30258052).  The FAD-dependent oxygenase str9 then catalyzes the key oxidative rearrangement responsible for the creation of the beta-methoxyacrylate toxophore (PubMed:30258052).  Str9 performs epoxidation of the 2,3 olefin of prestrobilutin A, followed by Meinwald rearrangement to furnish the aldehyde intermediate (Probable).  Rapid enolization of the aldehyde intermediate would give the beta-methoxyacrylate skeleton and methylations catalyzed by str2 and str3 complete the synthesis and lead to the production of strobilurin A (Probable).  The short-chain dehydrogenase stl2 and the dehydrogenase str4 play a role in the shunt pathway leading to the production of bolineol (PubMed:30258052).  The cluster encodes no obvious halogenase gene that could be involved in production of strobilurin B, nor any obvious dimethylallyl-transferase that could be involved in the production of strobilurin G (Probable).  It is possible that unknown proteins encoded in, or near, the cluster (such as str1 or stl1) may form new classes of halogenases or dimethylally-transferases, or that the responsible genes are located elsewhere on the genome (Probable).  Similarly, proteins encoded by str5/str6 hydrolases appear to have no chemical role in the biosynthesis of strobilurin A (Probable).  Finally, no obvious self-resistance gene is found within the cluster (Probable).
What are the official names of this protein?
Beta-lactamase-like protein str5, Strobilurin A biosynthesis cluster protein r5.
What is the protein family that this protein belongs to?
Belongs to the beta-lactamase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TRMFO_RHOPS
Sequence: MISAVLTTQPVHIIGAGLAGSEAAWQVARAGIRVVLHEMRPDRMTQAHKTDGLAELVCSNSFRSDDAANNAVGLLHAEMRKLGSLVMRAADANQVPAGGALAVDRDGFSAAVTKALAEHPLIEIRREEIGGLPPEDWGNVIIATGPLTSAPLAEAIRALTDESALAFFDAIAPIVHRDSIDMSVAWFQSRYDKAGPGGSGADYLNCPMTREQYDGFVDALIEGEKVDFKDWERDTPYFDGCLPIEVMAERGRETLRHGPMKPVGLTNPHNPLVKSYAIVQLRQDNKLGTLFNMVGFQTKLNYGAQQRVFRTIPGLENAEFARLGGLHRNTFLNSPKLLDPQLRLRAAPRLRFAGQMTGCEGYVESAGIGLVAGLCAAADAIGQTLAAPPPTTALGALLGHITGGHIETIDAGPRSFQPMNINFGLFPPLATAPTHGPDGKKLRGPEKSVAKKQALSARALADLDRWIGDCLKLPAAA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_STRZJ
Sequence: MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYFSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGVGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEKRMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHD2_STAAU
Sequence: MMLSNLLILPMLLPFLCALILVFLKNNDRISKYLYLGTMTITTIISLMLLIYVQRHRPITLDFGGWSAPFGIQFLGDSLSLIMVTTASFVITLIMAYGFGRGEHKANRYHLPSFILFLSVGVIGSFLTSDLFNLYVMFEIMLLASFVLITLGQSVEQLRAAIIYVVLNIIGSWLFLLGIGLLYKTVGTLNFSHIAMRLNDMGDNRTVTMISLIFLVAFSAKAALVLFMWLPKAYAVLNTELAALFAALMTKVGAYALIRFFTLLFDQHNDLIHPLLATMAAITMVIGAIGVIAYKDIKKIAAYQVIISIGFIILGLGTNTFAGINGAIFYLVNDIVVKTLLFFIIGSLVYITGYRQYQYLNGLAKKEPLFGVAFIIMIFAIGGVPPFSGFPGKVLIFQGALQNGNYIGLALMIITSLIAMYSLFRILFYMYFGDKDGEEVNFKKIPLYRKRILSILVVVVIAIGIAAPVVLNVTSDATELNTSDQLYQKLVNPHLKGED
What is the function of this protein?
Expression of the mnh2 operon in E. coli is not able to catalyze Na(+)Li(+)/H(+) antiport.  It does however confer higher growth rates than the control strain at up to pH 9. 5.  The operon may encode an NADH-ubiquinone oxidoreductase.
What are the official names of this protein?
Putative antiporter subunit mnhD2, Mrp complex subunit D2, Putative NADH-ubiquinone oxidoreductase subunit mnhD2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENGB_BACC1
Sequence: MKVTKADIVISAVKPEQYPDGDLPEIALAGRSNVGKSSFINKILNRKKLVRISSKPGKTQTLNFFLINEMMHFVDVPGYGYAKVSKTERAAWGKMIETYFTTREQLDAAVLVVDLRHKPTNDDVMMYDFLKHYDIPTIIIATKADKIPKGKWQKHLKVVKETLDIESGDEVVLFSSETGLGKEEAWKAIHKFTKTKNA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: YG64_SCHPO
Sequence: MDSVSNVSVNEQGKFNDKEEGFSNLKSLKHVSHSETDFEVSNDEDNQLLELGYKPVFKREFSTWATFSFAFSISGLFATVVTTYSYPLISGGAPSAVWCWLIAGAGCMCIALSVAELVSAYPTSGGLYFTCKDLVPARSMPVVAWVVGWLNLLGQAAGVSSTDWSCAQLLLAAVSISTDLKYIPTNQHIVGVMAAVIVFHGLVNSLSTRWLDRITRFYATFHLIVLVVCMICLLAKCPKFNTGKYVFTDVQASSGWHPIGFSFLFGFLSVAWCMTDYDATAHIAEEIENAAVRAPNAIALALSITYVLGWVFNIVLAFTMGTDLDSLINSELGQPVAQIFYNVLGKKGSMAFTILSFIIINFTGITAMQANARTIWAFSRDQALPFSRYWYKINKTTTTPVIAVWLNVVFCIALNLIGLGSIEAIEAIFSVCAIALDWSYVIPIACKLIFGKRLNYKPGPWNLGWASHFVNAYAVCWTAFVSVIFLMPTVRPVTPQNMNYAVVVLAGVLLFSLVYWWSGARKSYIGPRINVDMESEDPFKTE
What are the official names of this protein?
Uncharacterized amino-acid permease C15C4.04c.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
Protein: NDK_BORBR
Sequence: MSIERTLSIIKPDAVAKNVVGQIVARFEQAGLKVIAARMQQLSRTDAERFYAVHKERPFFKDLVDFMVSGPVFVQVLEGESAIQKNRDLMGATDPKKAAPGTIRADFADSIDANAVHGSDAPETAAVEVAFFFPEINIHSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OST48_BOVIN
Sequence: MATRAARVWSGWWLLLLPLLGLAGASGPRTLVLLDNLNLRETHSLFFRSLKDRGFVLTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDVSDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDAFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIEQLSDGKWVPFDGDDIQLEFVRIDPFVRTFLKRKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSVVFLHMKEKEKSD
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (By similarity).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (By similarity).  Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, DDOST 48 kDa subunit, Oligosaccharyl transferase 48 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the DDOST 48 kDa subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: WALK_MAMSC
Sequence: ITIVLGFFIARTITKPISDMRNQTLEMSKGNYTQRVKIYGNDEIGELALSFNNLSKRVQEAQANTESEKRRLDSVITHMSDGVLATDRRGRVRIINEMALKMLGLECADVEAKHILDILNIDDDYSLDDLQENNDSFIIDINSEEGIIARVNFSTIIQDTGFINGYIAVLHDVTEQHILENERREFVANVSHELRTPLTSMRSYIEALEEGAWRDPEVAPTFLNVTREETDRMIRLVNDLLQLSKMDSSSDQMNSELINFNMFINKIINRHEMSQGKNVTFIRDIPVKGLFVEIDPDKMTQVFDNVITNAIKYSQESHKRVEFHVKQNTLYNRMTIQIKDNGIGIPVNKVDKIFDRFYRVDKARARKMGGTGLGLAITKEIVEAHKGRIWASSKEGQGTSIYITLPCEVMEDEFGDWDA
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR.  WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR.
What are the official names of this protein?
Sensor protein kinase WalK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL13_PAEAT
Sequence: MRTYTPKPGDINRQWHVIDATDVVLGRLASQTATLLRGKHKPTFASHMDMGDFVIIINAEKVALTGAKLEQKRAYRHSGYPGGLTSVNYAELLESNPVRAVEKAIKGMLPKNSLAAQQLGKLKVYAGPEHPHAAQQPKTFEITQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: SDX_SACS2
Sequence: MVWKRTISAKALEKAKSAAVKVEDKVVFIANIKGTLYAMDAVCSHARCILDQLDEEKLTVKCYCHQALFDLRSGKMLEPPYVAPDAPKEKLGLKTYQIRDNGGWIEVDV
What are the official names of this protein?
Probable sulredoxin.
What is the protein family that this protein belongs to?
Belongs to the SDX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPA_ARTGP
Sequence: MVLITQLGAALAVFSALTVAAPTKGKARFSAPQVGIPKKAKHHPAAAYARALHKFGMKIPKAVSDAAKGSVPTTPTQNDEQYVTQVTVGGSTLNLDLDTGSADLWVFSTETPQDESQGHNIYKPSSGAKRLDGYSWEIKYGDSSSAHGDVFLDTVTVGGVTTSSQAVESAKEVSSQFVKDKATDGLMGLSFSVLNTVQPQPQKTFFDNVLSQLEQPLFTCTLKHGEPGTYDFGYIDDSKHTGEIAYTQVDNSNGWWGFTADGYSIGGGSNSSYSLYGAQHKRANGGSISGIADTGTTLMLLSDDVVGDYYQNVQGATQDQMQGGWVFPCDANLPDFILNIGGYNAVVPGKFMNFQEIDNSMCFGGLQSSGGGSTPNIFGDVFLKSQFVVWDTQGPRIGFAPQA
What is the function of this protein?
Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates.  The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site.  Shows a broad primary substrate specificity.  Favors hydrophobic residues at the P1 and P1' positions.
What are the official names of this protein?
Aspartic protease pepA.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYGB_AGRFC
Sequence: MPDLLLELRSEEIPARMQRKAAGDLKKLVTDALVERGLTYEGAREYWTPRRLTLDIRGLNARSADVREEKKGPRTDANEKAIEGFLRGAGLNDISEAQVVSDPKKGDFYIAIINKPGRPAEEIIAEVMPGIIRSFPWPKSMRSGPASMPKGSSYAGIEGKGSESLRWVRPLQSIVCLFGPEHDETQVIPFVIDGIVAGNITYGHRFHAPGPITVRRFEDYVSNLEKAKVILDADRRKDIILHDAKDLAFANGLELVEDEGLLEEVSGLVEWPQVLMGTFEEDYLQIPAEIIRLTIKTNQKCFVTRNQGAEEGLSNRFILISNIEASDGGKEIIHGNGKVVRARLSDARHFWNRDQGDLPDLETLKDSAAKFDLDLKKPLDQRMAKLDALNVTFHAKLGTQGERVARIRELAKALAPVVGADGALVDRAVVLAKADLRTEAVGEFPELQGLMGRKYAVLQGENESVAAAIEDHYKPQGPSDRLPADKVAITVALADKLDTLVGFWAIDEKPTGSKDPFALRRAALGVVRILLEKNVRLPLLSVARDSDLLSFFHDRLKVYLRDLGARYDLIDAVLTPESDDLLMIARRVEALTAFITGEDGRNLLAGAKRATQLLAAEEKKGTVVADGVSEELLKLDAEKALYAAIKTASADAAKAVEGEDFRSAMQALSTLRAPVDKFFEDVLVNDEDAAIRANRLALLKAIREATGTVADFSKITG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_STRP3
Sequence: MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDLSENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTDKDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: UNG_STAAR
Sequence: MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKPAQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANTYLESVGKSPINWCESEA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_PECAS
Sequence: MFDVLMYLFESYIHNETEMRVDQDTLTDDLTRAGFHRNDIYSALSWLEKLADIQEGQTAPLYLASDPLAMRIYTQDEELRLDAECRGFLLFLEQMQVLNLETREMIIERVMALETQEFDLEDLKWVILMVLFNVPGCENAYQQMEELLFEVNDGYVQ
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: AROQ_SACEN
Sequence: MKVLVLNGPNLGRLGKREPAVYGSTTYADLVSLCEGTAKELGIDVEVRQTDHEGEMVGWLHEAADHGLPVVLNAAAWTHYSVAVRDAASQVEAPLIEVHISNVHKREEFRARSYLSDIATGVVVGLGVRGYALALRWLAEESV
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PSB1_SULIA
Sequence: MVIMGNELQLENKILKGTTTVGIKVNDGVVLAADRRASAGFFVANKMVRKVLYITDKIGITTAGSVADLQFIYDVLKNIYHYNSITKYGPISIKGIATRLANVLSATKYFPYIVQILIGGYDDQPRLFNLDYLGDITEENYVATGSGSPVAMGVLEDEYNPKMTLDEAADLAKRAVFSAIKRDSFTGTGVIVAKIHSKGHEELEFYLNKKV
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PsmB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_STRTD
Sequence: MKRFISAWNRTSLIKRIAIGVVIGAILGLLIPKITVIGLLGDMFVGGLKAIAPLLVSALVANALSQTREGQQSNMKTVIVLYLFGTFAAALTAVISHYIFPISLKLGAASATKAAAPQGIGEVFKDLMLKMVDNPINALSQANYIGVLVWAVVFGFAMRTASEHTKELLHTLAEVTSQIVRWIINLAPFGILGLVFDTISKNGVGVLADYGVLILVLVGTMTFVALVINPIIAFVMMGKNPFPLVFRCLKDSGITAFFTRSSAANIPVNLQLCEDLGLNPDTYLVSIPLGSTINMAGAAVTINVLTLAAVTTLGIEVDFATAFILSVVSTISACGASGIAGGSLLLVPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAVAEKSRWKKS
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1842_PEDPA
Sequence: MKIIIAPAKKMQVDTDSFDATTMPVYLKQTQKILTMMKQLTYSDLKMLWKCSDKLAQLNYERLQGLDLKYQLTPAIMAYVGIQYQYMAPDLMTEKQLAYIQEHLRILSGFYGVLRPFDGIVPYRLEMQAKLKIDNYNNLCQFWGAKLYQNLYKDNRAVVNLASKEYEKAVRPFLQEDDKMTTCIFGEIIDGKVKQKATPAKEARGEMVNFMALNQVKNTKELKSFDRLNYAYRADLSSADKMVFIKNELHK
What are the official names of this protein?
UPF0246 protein PEPE_1842.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: AROB_LEPIC
Sequence: MSLIETVPVNTEHKSVPVHLHSNLSGLSEEIAKLPGVTSVFLITEKSIHSIYSKYLERELSSLPIKTIYIKGGEKSKHINRTGEVYNQLIEYGADRKSLILAFGGGVVGDFAGFIASTYLRGIRFVQIPTTLLACVDSSVGGKVAVNADFGKNMIGSFYQPEFVFAPLSVLSTLPDREWKCGQAEIIKHSLLSGGEYWEKVKTHSFKDLNVDSTILPYLIAESVRFKANVVSSDEKETGLRKILNLGHTTAHAIESVTKYKKYSHGEAVAIGLVTALLLSEQHSELDPVTTKETIESLKNYGLPFQTKLKSKQLAKHMLHDKKNVGGSIRFVLLKSPGSPIFDIPINSEDIILAIHKQKGI
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALAT2_HUMAN
Sequence: MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERILTLESMNPQVKAVEYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA
What is the function of this protein?
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.
What are the official names of this protein?
Alanine aminotransferase 2, ALT2, Glutamate pyruvate transaminase 2, GPT 2, Glutamic--alanine transaminase 2, Glutamic--pyruvic transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
Protein: MRAY_AQUAE
Sequence: MLYQLALLLKDYWFAFNVLKYITFRSFTAVLIAFFLTLVLSPSFINRLRKIQRLFGGYVREYTPESHEVKKYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAVGHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTGGKRLFKRAPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.