PharMolix/UniProtQA huggingface dataset:
Protein: DAPB_PARBD
Sequence: MAAEKGGSSDEERKPLTRGSMEYRDSSNSLHYSSSAASLSLAVIDRINGSTHDTGPDEIGRGDRDYSDDGEYDLEEADYIPSGGKPVQKKVKIVLGFLLFLCLSGWSLAFVLFLFGGHESSKTSIVYEDNISDTGSQGIKITLDEVFDGTWSPNSRDISWIPGPNGEDGLLLEKGASISNGYLRVEDIVSRKDPKSSKKPIVLMQKAYFNVSGEAVFPSRVWPSPDLKTVLVLSNEEKNWRHSFTGKYWLFDVESQTGQPLDPAAKDQRVQLASWSPRSDAVVFTRDNNMFLRKLSSNEVIKITTNGGVNLFYGVPDWVYEEEVFSGNSVTWWADDGEYIAFLRTNESSVPEYPVQYFVSRPNGEIPKPGGESYPETRKIKYPKAGAPNPIVDLQFFDVGKDEVFSVDIKGDFADSNRLIIEVVWASNGKVIVRSTNRESDVLHVAVIDVLSRTGKIVRKEDINALDGGWVEPSQTTRFIPADPDNGRLNDGYIDTVIYEGRDQLAYYTPIDNPKPIVLTNGHSEVVQAPSGVDLKRGLVYFVVAGNEPWERHIYSVNFDGTSLQPVTNVSESSYYDVSFSNGAGYAFLKYAGPQVPWQKVISTPANEVTFEETIEENNHLSERLRQYTLESKIYQYIDIDGFSLPVLERRPPNFNQTKKYPVLFYLYGGPGSQTVKKKFNVDFQSYVAANLGYIVVTVDGRGTGFIGRKARCIIRGNLGHFESLDQIQAAKIWAAKPYVDESRISIWGWSYGGFMALKTIEQDGGRTFKYGIAVAPVTDWRYYDSIYTERYMHTPQRNPGGYDNAAISNTTALANNIRFLVMHGTADDNVHIQNSLTFIDKLDVNNVHNYDVHFFPDSDHSIYFHNAHKIVYSRLADWLVNAFNGEWLKTYDPTPNDSILRRAATWVGMSI
What is the function of this protein?
Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Probable dipeptidyl-aminopeptidase B, DPAP B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Note=Lysosome-like vacuoles.
Protein: DPOL_FOWPN
Sequence: MDIRCVNWFENKGETKYIYLKAINRESNVIFIRFNYYYHYVYDASKELEYKPNECIDLGPFKIINIDEKLSTDIRYVEPRNYYTSELVLVKDLKRNREKQYLQEYLDITWFYLLNNITPDGCYKIDIEHLTPIKKDCYHCDDVSKVFIQEIPIFEVKFTYLLFDIECQFDKKFPSVFVNPISHISCWIIDKVTEYKFTLINTDILPDKEPSILHHKDFSPKDRITYCTEIVMLLIMKKILEHRFDFVITFNGNNFDIRYISGRLEILEKSFIYFSLPDATETVKLKIFERFVTGGTFTNKTYHINNNNGVMFFDLYAFIQKTERLDSYKLDSISKNIFNCNVAIKEIDDTILTLEATVKDNSKDKLSIFSRVLETGNYITIGDNNVSKIVYKDINQDSFIIKVISNRDYEIGSVHNISFGKDDVDLKDMYKNYNLEIALDMERYCIHDACLCKYIWDYYRVPSKINAASSTYLLPQSLALEYRASTLIKGPLLKLLLEERVIYTRKITKVRYPYIGGKVFLPSQKTFENNVMIFDYNSLYPNVCIYGNLSPEKLVCILLNSNKLESEINMRTIKSKYPYPEYVCVSCESRLSDYYSEIIVYDRREKGIIPKLLEMFIGKRKEYKNLLKTASTTIESTLYDSLQYIYKIIANSVYGLMGFSNSTLYSYSSAKTCTTIGRNMITYLDSIMNGAVWENDKLILADFPRNIFSGETMFNKELEVPNMNESFKFRSVYGDTDSIFSEISTKDIEKTAKIAKHLEHIINTKILHANFKIEFEAIYTQLILQSKKKYTTIKYLANYKPGDKPIRVNKGTSETRRDVALFHKHMIQRYKDMLMKLLMESKGQQEITRLILQSLETDMISEFTHNREFEKYLLSRKHHNNYKSATHSNFELVKRYNLENTEKIEIGERYYYIYICDISLPWQKKLCNILSYEVIADSKFYLPKDKRIFYEIYFKRIASEVVNLLTDKTQCMLFFSRLFGTKPVFSSD
What is the function of this protein?
Catalyzes DNA synthesis.  Acquires processivity by associating with a heterodimeric processivity factor comprised of the viral A20 and D4 proteins, thereby forming the DNA polymerase holoenzyme.  Displays 3'- to 5' exonuclease activity.  Might participate in viral DNA recombination.  Does not perform translesion synthesis across an abasic site (By similarity).
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: FTSH_VAULI
Sequence: MKSWSVNKIIMLISLFLLEVIDSQIISNNIINNFNTKQNSNNIKMTYGRFLEYLDMGWIKKVDFYDNGRIAIIEASSPELGDRLQKIRVEIPVGDSPLIVKLRTAKVDFTAHSTINSKGIFTQLSNIFIPLIIIIGLIFLFRRSTNFMSGPGQLMSFRKARAKVQTEINTDVVFDDVAGIDEVKEEFEEVVTFLRKPQRFLSVGAKIPKGVILIGPPGTGKTLLAKAIAGEAGVPFISISGSEFVEMFVGIGASRVRDLFKTAQQNAPCIVFIDEIDAVGRQRGAGIGGGNDEREQTLNQILTEMDGFKENTGIIVIAATNRVDVLDGALLRPGRFDRQVSINLPDIKGRLEILKVHAKNKKLDSNISLGLIAQRTPGFSGADLANLLNESAILTARRNKFAITMSEVNTAIDRLLAGLEGTSLTDTKNKRLIAYHEIGHAVIGTLLKYHDEVQKVTLIPRGQARGLTWFIPNDEQALISRGQLVARIIGTLGGRAAEEVVFGSSEITTGASNDLQQITNLTRQMVTRLGMSTVGPISLDANVEQVFIGRGIKNNNEFSASVANKIDDQVKIIIKHCYDQAVNIIKQNRFLIDQLVNTLIQEETISGNDFREQINNYTKLPKKLSTLSEKNNVNPKITESFVVF
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein; Stromal side.
Protein: ARHGA_MOUSE
Sequence: MEQGEASPPVPAEHEAKCDTSNNEEEGELFDFDSGDEVPEADRQVPSADDRTRGAEAGGADENTCPAGNGTGAEPAPEAEPAKLVVPTKVNPYSVIDITPLQEDQPSSPDANTEEEGVGLRVPSGYSVPVPCGYAVPSNLPLLLPAYSSPVIIRAESVEEEEAAETVGDGQCNSLSSEDLPHSSEQGSQEGSALARWAADPANTAWMENPEEAIYDDVPRENSDSEPDEMIYDDVENGEEGGNSSPEYGWSSSEFESYEEPSDSEGKNGIPRSFLRSSHKKQLSHDLTRFKAHCEEKMRGLVASTVGAMEIQQAKQRQERKMQKLMKAAKEGTKDGLEKTKAAVKRGGSFIRTRSLVSQDHRCYFEEEQNLFIDVDCKHPEAVLTPMPEGLSQQQVVRRYILGSIVESEKNYVDALRRILEQYEKPLSEMEPRLLSDRKLRMVFYRVKEILQCHSMFQIALASRVSEWDVVETIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPAFLEFLKLSQDSSPDRVTLHSLMMRPIQRFPQFILLLQDMLKNTAKGHPDRLPLQMALTELETLAEKLNERKRDADQRCEIKQIAKAINERYLNKLLSSGNRYLVRSDDVIETVYNDRGEIVKTKQRRIFMLNDVLMCATASSRNSHESHAVMSQRYLLKWSVPLGHVDVIQYNGGSGAGEHCRHHAAHSPESLAVVANAKPHKVYMGPGQLYQDLQNLLHDLNVVGQISQLIGNLRGSYQNLNQSVAHDWTSGLQRLILRKEDAIRAADRCRIQLQLPGKQDKSGRPTFFTAVFNTLTPAIKESWVSSLQMAKLALEEENHMGWFCVDDDGNLAKKETHPLLVGHMPVMVAKQPEFKIECAAYNPEPYLSNESQPASPSTARGFLWIGSCSNQMGQVAIVSFQGSNPKVIECFNVESRILCMVYIPAEESKPQETTETKDPEATASRAPHVPTICLGTEEGSISIYKSSQGCKKVRLQHFYAPDKSTVMSLACSPQGLYAGLVNGSVASYTKAPDGSWNSEPQQVIKLGVLPVRSLLLVEGALWAASGGQVFMASVETHTIENQLEAHQDEGMVISHMAVAGVGIWIAFTSGSTLRLFHTETLKHLQDVNIDAPVHSMLPGHQRLSVTSLLVCHGLLMVGTSLGVVVALPVPRLQGIPKVTGRGMVSYHAHNGPVKFIVSATAFQNKDRARDSPRSGSELQDEDPKDLLCSEEGPSCPGQPDTYTSVWLGDSLGLPTQKNDLSSSSGSLNLSHGSSSLEHRSVDSSLCDLLRDPSASPRSRPQGSRRARASSALVVCGGQGHRRVHRKARQPSQEDLVSSVMVWQIPLLGM
What is the function of this protein?
May play a role in developmental myelination of peripheral nerves.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 10.
Protein: ESFU3_ECO57
Sequence: MINNVSSLFPTVNRNITAVYKKSSFSVSPQKITLNPVKISSPFSPSSSSISATTLFRAPNAHSASFHRQSTAESSLHQQLPNVRQRLIQHLAEHGIKPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLVQHLAEHGIQPARNMAEHIPPAPNWPAPPLPVQNEQSRPLPDVAQRLVQHLAEHGIQPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS
What is the function of this protein?
Required for efficient pedestal formation in host epithelial cells during infection.  Acts as an intermediate between Tir (via host BAIAP2) and host WASL/N-WASP.  Directly binds and activates WASL/N-WASP, which stimulates actin polymerization and leads to the formation of actin pedestals at the sites of bacterial adhesion.
What are the official names of this protein?
Secreted effector protein EspF(U), EspF-like protein encoded on prophage U, Tir-cytoskeleton coupling protein TccP.
What is the protein family that this protein belongs to?
Belongs to the EspF(U)/TccP family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via the type III secretion system (TTSS). In host cells, localizes to the tip of the actin pedestal (By similarity).
Protein: WDR6_SCHPO
Sequence: MLVEGDKGVLEPVNFVGPVTSLALIHNDKFLCCAQGPCLRIYDVSESRHESDLIKSILLPFHNRIHGMLPCKQGLFVWGGTYFAVVDVETSQVYYDRISDWIFNAAELGEENKFCVVTSKNQVHLLSLSKGSWEVTNTISCEKTPLLFCATVQISGNEIYIASASAFQQIYVWKFNYNNPPSCVSIDTYLVGHEGACFDLKFSSDGRYLCSVSEDRTLRLWSIESSPFLIATGFGHSARVWRCVFLPNKEIATVSEDLTLRLWTWNDKTLTNTYTYTGHRGKHIWSLVVSSANPIIYTGGNDGSVRSWDYKTRIQESCISVSSLFTSKTLLASFCFVKCQKLLCLAKNGEMSIIDNKGKKAIPALTTTSDMSIIRSWKNSFFVAAASNKGTIYVFSYQNTNLLKAIDLHRGKIQQLLTYQVKERYFLLSKSFVGKNQFRVYLQEFDFEADKVNLISTIELELPATFDPTSLTVDEEYSNFLIGSRTGSLALYNIGESNYLSVWRRIHEFDAISSIHIKSSKRDYLLIQTVGRDGYVNLFSIPRVEKSAVPQELCSKKCCDGILSGGLCKKLKNGKENQWVWGFHASNFFLRDETNETNVFFIDCGGSHRPWAFSMEMDIQSFASYRANQLYIYSTALNLLQRNSVLQNGLHGREIRAMDFNPSGDLLLSGSEDTKVTLLEFQSNGNIIPLNSVKFHNSGIQSLTWFSDDILFSTGGLEELNVYRLIQKPEAYLKRIVHEKLCKPNKSNKTYDGDLRITDISVVKATHLGERVLWINTVQSDSTIKAFTYNVDTKQLNCIKSWKYKTVCLVFAEAVIFGSHLLLVVASTDGNVAIWNTFWRDPQIEPLIIWIKTVHQFCVKSLNISRDQDVLTISTGGDDGAISRSILLLEQISENSVVVNSLHNYFFAEAHASSVTGVLSITKELLLSVSIDQRILLWKVEGDSLKPILERYTHVADVGGMIRNNDFLIIYGIGCEVFRLGSLR
What is the function of this protein?
May play a role in the regulation of the retromer complex and in the recycling from endosomes of plasma membrane proteins.  May be involved in the methylation of the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of tRNA(Phe) and tRNA(Leu(UAA)) by SPAC4F10. 03c (By similarity).
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C1306.02.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS3A2_YEAS2
Sequence: MAVGKNKRLSRGKKGLKKKVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKNASDALKGRVVEVCLADLQGSEDHSFRKVKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTREVQNSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGKEKGKKVSGFKDEVLETV
What are the official names of this protein?
40S ribosomal protein S1-B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILB3_CAEEL
Sequence: MKLSVVLALFIIFQLGAASLMRNWMFDFEKELEHDYDDSEIGFHNIHSLMARSRRGDKVKICGTKVLKMVMVMCGGECSSTNENIATECCEKMCTMEDITTKCCPSR
What are the official names of this protein?
Probable insulin-like peptide beta-type 3.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATB_BIFLS
Sequence: MAEKLMKYADATKKYDVVFGLETHVELSTNTKLFCPAHIEFGGEPNTELTPVSLGLPGSLPVINKTAVDYAIKLGLALHCEIAEWSQFARKNYFYPDMPRDYQISQYDKPTNGNGYLDVELEDGTVFRVPIERAHIEDDAGKNTHVGGADGRIEGADHSLVDYNRAGVPLIEIVTKPIEGAGDRAPEIAGAYVRAIRDIVRALNISHARMEQGNMRADVNVSLRPSPDAPYGTRSETKNVNSFRGIEKTIQYEIRRQAARLDDGKEILQETRHWDEATQTTAGGRLKSDADDYRYFPDPDLVMLHITKEHIEEMKAQMPEMPRERRNRLKSEWGLSDLQMRDILNADALDLIEETVKAGAKAAGARKWWLGELSREANAKGVSLEELPITPADVAEVEKLIASGKLNDKLAKQTVEGVLKGEGTPDEVVKKHDYKIVEDNGAIEAAVDAAFEANPDVVEKLKSGNMKPMGVIIGAVMKATRGQADAKAVTKVVMGKIKG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: STKLQ_ARATH
Sequence: MVSVQNLKTDQLLNFLFKNPTKFLSRFSPMAKNKTLVTPSTVKKSSDVASTSKKLSGVASPAKKPSGVTSPVKKPLEAVASTSSEEEEEDEPSSDSESGSESESDTEAEPMTLAAAAPSSSNEKRQSEGKPEEERAKTETETGKKPLLFQRLWTDEDEIVFLQGMIKFAKDTGKNVSEDMNGFFEKLKDSISFEVKTDQFVNKIRSMKRKYIENKKTTTEHDKKCYELAEIIWVSDGDATALVKPKKKKLKVDEESDWFERSFVDGAFKELGPGVDEETWKKNWSLVPVKKRKRIEEKVKSMQADELKTTWQKIDVVHEMRSLMAKYV
What are the official names of this protein?
Probable transcription factor At4g00610, Storekeeper-like protein At4g00610.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
Protein: MY105_ARATH
Sequence: MEMVHADVASLSITPCFPSSLSSSSHHHYNQQQHCIMSEDQHHSMDQTTSSDYFSLNIDNAQHLRSYYTSHREEDMNPNLSDYSNCNKKDTTVYRSCGHSSKASVSRGHWRPAEDTKLKELVAVYGPQNWNLIAEKLQGRSGKSCRLRWFNQLDPRINRRAFTEEEEERLMQAHRLYGNKWAMIARLFPGRTDNSVKNHWHVIMARKFREQSSSYRRRKTMVSLKPLINPNPHIFNDFDPTRLALTHLASSDHKQLMLPVPCFPGYDHENESPLMVDMFETQMMVGDYIAWTQEATTFDFLNQTGKSEIFERINEEKKPPFFDFLGLGTV
What is the function of this protein?
Probable transcription factor that involved in boundary specification, meristem initiation and maintenance, and organ patterning.  Functions in both lateral organ separation and axillary meristem formation.
What are the official names of this protein?
Transcription factor MYB105, MYB-domain transcription factor LOF2, Myb-related protein 105, AtMYB105, Protein LATERAL ORGAN FUSION 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SD31_ARATH
Sequence: MKMLRALLLCLSLVFFLAFQIVVSEIQLGSKLVVGENTLWVSNNGDFALGFFNPPGLLNRFSIGIWFNSNSIPYDQRKVVWVAGAGVVVSDNSSYFELTRNGELVLFDSLLGVPVWNSKTNRFSVSSALLRDDGNLVLLKDREEIVWQSFGTPTDTLLPNQKFPAFEMLRAASENSRSSYYSLHLEDSGRLELRWESNITFWSSGNEVVKKKKKKKNIGAVLTSEGALFLEDQDLMRPVWSVFGEDHNDTVKFRFLRLDRDGNLRMYSWNEDSRIWKPVWQAVENQCRVFATCGSQVCSFNSSGYTECNCPFNAFVSVSDPKCLVPYQKPGCKSGFNMVKFKNLELYGIYPANDSVISQISSQRCKKLCLENSACTAVTYTNDGEPQCRMKLTRYISGYSDPSLSSISYVKTCLDPIAVDPNNVSKESPVTVTKSHSICIPCLVGATSTTLVLFLGFQLGIVVYIYRRKKKLAKKKAERFSKATNPKGVMIFSVDEIKAMTDNFDNNIGPQIFKGVMPENELVAVKEVEATLTEERKFRSSASKIGTMHHKNLANLEGYCCELGRRFLVYEYAKNGSILDHIVDPLRSKKLTWRIRTDTCLSVAKALCYLHMECREFVSHGNLNCGNILLGEDLEAKLTEYGFGLCAADKDVEDFGKTVLALITGRYEPEGVVSEWVYREWIGGRKETVVDKGLEGCFDVEELERVLRISFWCVQTDERLRPSMGEVVKVLEGTLSVDPPPPPFACARSSPTNSSESSQSLYEP
What are the official names of this protein?
G-type lectin S-receptor-like serine/threonine-protein kinase SD3-1, S-domain-3 (SD3) receptor kinase 1, SD3-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CCMO_SYNP6
Sequence: MSASLPAYSQPRNAGALGVICTRSFPAVVGTADMMLKSADVTLIGYEKTGSGFCTAIIRGGYADIKLALEAGVATARQFEQYVSSTILPRPQGNLEAVLPISRRLSQEAMATRSHQNVGAIGLIETNGFPALVGAADAMLKSANVKLICYEKTGSGLCTAIVQGTVSNVTVAVEAGMYAAERIGQLNAIMVIPRPLDDLMDSLPEPQSDSEAAQPLQLPLRVREKQPLLELPELERQPIAIEAPRLLAEERQSALELAQETPLAEPLELPNPRDDQ
What is the function of this protein?
Required for formation of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, rbcL-rbcS) is sequestered.  Required for recruitment of major shell protein CcmK2 to the pre-carboxysome.  Suggested to be a carboxysome shell protein.
What are the official names of this protein?
Carboxysome assembly protein CcmO, Carbon dioxide concentrating mechanism protein CcmO.
What is the protein family that this protein belongs to?
Belongs to the bacterial microcompartments protein family.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes.
Protein: ULAC_SALPA
Sequence: MKLRDSLAENNSIRLQAEANTWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYFVIAPGLAMPHGRPEEGVKKTGFSLVTLKKPLEFNHEDNDPVDILITMAAVDANTNQEVGIMQIVNLFEDEANFDRLRACRTAQEVLDLIDRTNAAA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIA component, Ascorbate-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB1F2_I34A1
Sequence: MGQEQDTPWILSTGHISTQKRQDGQQTPKLEHRNSTRLMGHCQKTMNQVVMPKQIVYWKQWLSLRNPILVFLKTRVLKRWRLFSKHE
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: MAP2_PYRFU
Sequence: MDTEKLMKAGEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGGKPAFPVNLSINEIAAHYTPYKGDTTVLKEGDYLKIDVGVHIDGFIADTAVTVRVGMEEDELMEAAKEALNAAISVARAGVEIKELGKAIENEIRKRGFKPIVNLSGHKIERYKLHAGISIPNIYRPHDNYVLKEGDVFAIEPFATIGAGQVIEVPPTLIYMYVRDVPVRVAQARFLLAKIKREYGTLPFAYRWLQNDMPEGQLKLALKTLEKAGAIYGYPVLKEIRNGIVAQFEHTIIVEKDSVIVTTE
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
Protein: SYH_PYRHO
Sequence: MIERVKGTRDFLPEDMAKRRWVFEKIREVFEAYGFKEILTPVMEYTKLFQLRSGEEVVKQLYAFKDKGGRDVSLRPDMTSSVARLYVNSFQMAPKPIKWYYIANMFRYEEPQSGRYREFWQAGVELIGSDKVEADAEVIALFVESYLSTGLRDFTVNIGDRILLDEFAGMLGVSDDIGLMRIIDKRDKLSQEEFINLLKEFGLGESEIEKVLELVEIKGRPDNVLPLAEELFKSKKAKEEISKLYKLTDLLEWYGVKDWIRIDLGIARGFDYYTSIVFEAISPNELGIGSIGGGGRYDNLIEIFGGKPTPATGFAIGIERLLPILEWKGLIPKPQTGPEVFVIPLKDMEKVAINIAVKLRREKIKTDIELSGRKLGKALDYANRVGAKLVIIVGKRDVERGVVTIRDMESGEQYNVSLNEIVDKVKNLLKR
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_BARQU
Sequence: MNIHEYQAKRLLHEYGAPIANGVAVYSIEQAEKWAKKLPGPLYVVKSQIHAGGRGKGKFKELDLDSKGGVRLAKSVEEVVANVKEMLGKTLVTKQTGPEGKQVNRLYIEDGADIERELYLSLLVDRAVGRVAFVVSMEGGMDIETVAEETPEKILTLPVDPVQGVTSADCKRLCDALELHDNARKDGEKLFPILYKAFCEKDMSLLEINPLIVMKDGHLRVLDAKISFDNNALFRHPDILELRDLSEEDPKEIEASKHDLAYVALEGTIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPNVKGILVNIFGGIMRCDVIAEGVVAAVREVGLKVPLVVRLEGTNIEQGKAIISDSGLNVISASDLDDAAQKIIAAVRGA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: VIRD3_AGRFC
Sequence: MANEEFTRHYAWPVPVASNDEGRGTARIPIQAQSIVAGEDGRDTSVPTALSRPPIEDMPHGVQETSASGGRLGAARLRDSVIPPGISEARTDLSAILRKKSGSFRTGMQYLRGLERENFDKQDREASALPDLSARGIKRPREIEYPGNASGLTIKRQDGLGIEINTISASSPVNRAAHSSNWQGAPEPGVYNVQPSADRAQNSAQESSTFPDGTSVSALYSGPLAEWFERDTGSETTRNSGNTISSPLRGLEEFGDSADSRYLGREAQSLSVTVTTPNSNAEASSHSAHTETLDDVSSDRSSEQGRGPLGAAILGSHHDLSPRAQKLSQTNRDSPELTDADLAKVDAVFESLSKGPPAGESAAPDFRERGPGSAFQKEGVSDRANGVPTNWEVPFGRGGGHSPQALRSSGVELDDFPDFTEAELAKIDALVESHSNRSLSVRNIVPDLRGAGADNVFRKEGVVERAEKMPIDSVSLTRLNGERSRSPKTSQASLEDFPDLTDADLAHIEESERIARTAVEKGKQKISTEADTRFDLGNSSAPRVSPRSVTPLVPNANQPITSWFYEAQKTCDKLVENTYVKPAVDSSRARNDVENTAARLGDPAPALGHDNLGRTRALTPVRDVMSRPSADRQLASHAAEHSAIDDIWKRDDRDRRTHPYRGLDSRSREGCGR
What are the official names of this protein?
Protein VirD3.
Protein: RB45A_ARATH
Sequence: MQQPPSNAAGAGQIPSGQQHLWMMMQQQQQQQQMQLSAAPLGQHQYGIGSQNPGSASDVKSLWIGDLQQWMDENYIMSVFAQSGEATSAKVIRNKLTGQSEGYGFIEFVSHSVAERVLQTYNGAPMPSTEQTFRLNWAQAGAGEKRFQTEGPDHTIFVGDLAPEVTDYMLSDTFKNVYGSVKGAKVVLDRTTGRSKGYGFVRFADENEQMRAMTEMNGQYCSTRPMRIGPAANKNALPMQPAMYQNTQGANAGDNDPNNTTIFVGGLDANVTDDELKSIFGQFGELLHVKIPPGKRCGFVQYANKASAEHALSVLNGTQLGGQSIRLSWGRSPNKQSDQAQWNGGGYYGYPPQPQGGYGYAAQPPTQDPNAYYGGYTGYGNYQQQRQ
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation.
What are the official names of this protein?
Polyadenylate-binding protein RBP45A, Poly(A)-binding protein RBP45A, RNA-binding protein 45A, AtRBP45A.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding RBP45 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNFE_SHESM
Sequence: MTNYREIAWQGLWKNNPGLVQLLGLCPLLAVTATLTNALGLGVATMLVLIGSNILVSLVRDYVPKEIRIPVFVMIIAALVTAVQLLINAYAYGLYLSLGIFLPLIVTNCIIIGRAEAFASRNNAFSAAFDGLMMGLGFTLVLAVLGATREILGQGTLFDGADQLLGPWAKALTIQVWQVDTPFLLAMLPPGAFIVMGLLIALKNVIDKKLKERQPEAAVQPSVTRARITKVS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURG_SHEWM
Sequence: MTNVSDEKRILIMAGGTGGHVFPALAVAKYLSKQGWKVRWLGTAERMEARLVPQHGFDIDFIDIKGVRGNGVVRKLAAPFKVLRSITQARVVIKEFQPDVVLGMGGFASGPGGVAARLSGIPLVLHEQNAIPGMTNKILSRIASQVLCAFEDTFDQVQAEVVGNPIREELIALGQTPKDAGAKESLKVLVVGGSLGAKVFNDLMPTVTADMSKTHLITVWHQVGKGNLQSVKGEYQRLGLDGSVSVAEFIDDMEAAYRWADVVLCRSGALTVSELAAIGLPSLLVPYPHAVDDHQTKNAQVLVKAGGAFLLPQPILDIDKLIGKLQILSSDRDELDQMGQRAKSVGVIDATQKVADVCIRLAGKS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2089_NEIMB
Sequence: MRLNHKQGEAGEDAALAFLQSQGCTLLARNWHCAYGEIDLIVKNGGMILFVEVKYRKNRQFGGVAYSISPSKLLKLQRSVEYYLQQNRLTNVPCRLDAVLIEGSRPPEWIQNITG
What are the official names of this protein?
UPF0102 protein NMB2089.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: UPPP_RHIE6
Sequence: MDYINAALLGVIEGITEFLPISSTGHLIIAEQWLGHRSDMFNIVIQAGAILAVTIIYWRRLLDLVLGWREPENRDYAAKLIVAFLITAILGLVVKKLGFELPETATPIAWALIIGGIWMIFAEWAAARKAPHKEITWLVAILVGIAQIVAGVFPGTSRSGATIFVAMLAGTGNRAAATEFAFLVGIPTMYAASGYELLKTFKDGGAAGEDWTALAIAFIVSTIVAFIAVKWLLAYIRSNRFTLFAIYRIILGVLLLGMATSGLIA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPLB_STAA1
Sequence: MNKNVVIKSLATLTILTSVTGIGTTLVEEVQQTAKAENNVTKIQDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
What is the function of this protein?
Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln.
What are the official names of this protein?
Serine protease SplB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.