PharMolix/UniProtQA huggingface dataset:
Protein: HIS5_ARCFU
Sequence: MIAIVNYGVGNLKSISKALETVGAKVSVTSDPEKIKCASGVVFPGVGAFKSAIEKLNLIRDVIDSLEVPILGICLGMQLFATESTEGGVYRGLDYIPGRVVRFPPSVGKVPHMGWNTLKITREAEILDGVESGEFVYFVHSYYMQTDDEFVISKTDYGIDFPSGVERENYIGFQFHPEKSGKVGLRILENFVNIVKR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MACBA
Sequence: MTNIRKSHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLILQIITGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFVCLFLHVGRGIYYGSYTFMETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPSGLNSDGDKIPFHPYYTIKDILGVLLLILILVSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALLPLLHTSKQRSLMFRPITQILFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFSIILIFMPISGIIEDKILKLY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LOLB_COXB2
Sequence: MSLISNNEERSLRVRYCIAIALSALLISGCTTLRLPNQSTSVYHQQTWAQRYYDLSRISQWNIDGAFSIQQPGKTIIAAYDWQQKGMNYRIRIHSSLDIYSVNISGRPGMVTLWRSPRQHYTASTPEQLMQQQLGWQLPLSNLYYWIRGIPAPGAYQADFDTYTHLIALQQSGWHIRFSQYTTVGSVDLPRTLQLSNGPLAVKIVVKHWQ
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SYC_HELP2
Sequence: MFIYDTKSKQKVPFEPLVQNKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVVLVRNFTDIDDKIINKAFKENKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAMVRMIETLLEKNFAYQVSNGDIYLDTSKDKDYGSLSMHNSSVEFSRIGLVQEKRLEQDFVLWKSYKGDNDVGFDSPLGKGRPGWHIECSSMVFETLALANAPYQIDIHAGGADLLFPHHENEACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFIKDALKNYDGEILRNYLLGVHYRSVLNFNEEDLLVSKKRLDKIYRLKQRVLGTLGGINPNFKKEILECMQDDLNVSKALSVLESMLSSTNEKLDQNPKNKALKGEILANLKFIEELLGIGVKDPSAYFQLGVSESEKQEIENKIEERKRAKEQKDFLKADSIREELLNHKIALMDTPQGTIWEKLF
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S13A5_MOUSE
Sequence: MDSAKTCVTKFKSFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANTAVEASLGTLELLDKNKTSELPGSQVVFEDPNVQEQEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSKDVLNYASWFGFAFPNMVMMLVLAWLWLQCLYMRHNLKKTCICCGEKKRDTEKIAYKVLNEEYQKLGSLSYPECNVLFCFTLLVILWFSRDPGFMPGWLSFAWVEGNTVHITDATVAIFVAILLFIIPSQKPKFNFSSQTEEERKTPFYPPALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTWGRAMFNLDNFPDWANSTSVNT
What is the function of this protein?
High-affinity sodium/citrate cotransporter that mediates citrate entry into cells, which is a critical participant of biochemical pathways (PubMed:35448538, PubMed:26324167, PubMed:14656221).  May function in various metabolic processes in which citrate has a critical role such as energy production (Krebs cycle), fatty acid synthesis, cholesterol synthesis, glycolysis, and gluconeogenesis (PubMed:12826022).  Transports citrate into the cell in a Na(+)-dependent manner, recognizing the trivalent form of citrate (physiological pH) rather than the divalent form (PubMed:12826022, PubMed:14656221, PubMed:26324167).  Can recognizes succinate as a substrate, but its affinity for succinate is several fold lower than for citrate (PubMed:26324167, PubMed:14656221).  The stoichiometry is probably 4 Na(+) for each carboxylate, irrespective of whether the translocated substrate is divalent or trivalent, rendering the process electrogenic (PubMed:26324167, PubMed:14656221).  Involved in the regulation of citrate levels in the brain (PubMed:32682952).
What are the official names of this protein?
Na(+)/citrate cotransporter, NaCT, Sodium-coupled citrate transporter, Sodium-dependent citrate transporter, Solute carrier family 13 member 5.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDHJ_PROM1
Sequence: MTNDSEIVVEEKISGPISDWLSNKGFENIPLKEDHLGIEVIKISPNNLLSIVEALKNDGFNYLQCQGGYDEGPGLNIVCFYNLIEMNELKEDISPREVRLKVFLDRNGDLTVPSLYSLFRGADWQERETFDMYGVNFKGHPHPKRLLMPEDWKGWPLRKDYVQPDFYEMQDAY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J, NDH-1 subunit J, NDH-J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EFTS_MARN8
Sequence: MAAITAAMVKELRERTGLGMMECKKALVEAEGNVETAIEELRKSSGLKAAKKAGRTAAEGVSLVKVSDDNTVAFILEVNSETDFVARDDNFMNFANDVLNVAFEKGETDVAKLMEGDLEAKREALVQKIGENITVRRIIKVEGPVVGGYVHSNNKIASVVALTAGNEELARDIAMHVAAVNPRVGKPDDMPAEELEKEKEIIKAQPDMEGKPAEIVEKMMGGRIKKFLAENSLVEQPFVKNPDQKVGDLIKSAGGDLVGFIRLEVGEGIEKEEVDFAAEVAAAAGTGKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_STAA3
Sequence: MFNQSYLNVYFICGTSDVPSHRTIHEVLEAALKAGITLFQFREKGESALKGNDKLVLAKELQHLCHQYDVPFIVNDDVSLAKEINADGIHVGQDDAKVKEIAQYFTDKIIGLSISDLDEYAKSDLTHVDYIGVGPIYPTPSKHDAHIPVGPEMIATFKEMNPQLPIVAIGGINTNNVAPIVEAGANGISVISAISKSENIEKTVNRFKDFFNN
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: TRPV2_HUMAN
Sequence: MTSPSSSPVFRLETLDGGQEDGSEADRGKLDFGSGLPPMESQFQGEDRKFAPQIRVNLNYRKGTGASQPDPNRFDRDRLFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQREFSGLSHLSRKFTEWCYGPVRVSLYDLASVDSCEENSVLEIIAFHCKSPHRHRMVVLEPLNKLLQAKWDLLIPKFFLNFLCNLIYMFIFTAVAYHQPTLKKQAAPHLKAEVGNSMLLTGHILILLGGIYLLVGQLWYFWRRHVFIWISFIDSYFEILFLFQALLTVVSQVLCFLAIEWYLPLLVSALVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLIYLVFLFGFAVALVSLSQEAWRPEAPTGPNATESVQPMEGQEDEGNGAQYRGILEASLELFKFTIGMGELAFQEQLHFRGMVLLLLLAYVLLTYILLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWCRKKQRAGVMLTVGTKPDGSPDERWCFRVEEVNWASWEQTLPTLCEDPSGAGVPRTLENPVLASPPKEDEDGASEENYVPVQLLQSN
What is the function of this protein?
Calcium-permeable, non-selective cation channel with an outward rectification.  Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator.  May transduce physical stimuli in mast cells.  Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
What are the official names of this protein?
Transient receptor potential cation channel subfamily V member 2, TrpV2, Osm-9-like TRP channel 2, OTRPC2, Vanilloid receptor-like protein 1, VRL-1.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Melanosome. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: MRAY_LISMF
Sequence: MSLYMLVSTFAVAFIITVIGVPLFIPFLVKLKFGQSIRDEGPKMHEKKSGTPTMGAVVFITAMLISFLIFSFISGEVSAATWLLFIALALFGALGFLDDYIKVVQKRNLGLTSKQKFLGQVAISILFYLVYHLNGFAETLNIPFTNIEVDLGWFFVIFILFWLVGFSNAVNLTDGLDGLVSGLSVIAFSAFGVIAFYQEQMDVAIFCFAIVGGMLGFLLFNKNPAKIFMGDTGSLALGGSIAAISILVHQEWLLLLIGIIFVIETASVILQVFYFKATGGKRIFRMTPIHHHFELGGWSEWRVVLTFWGIGLIGAIISVCVVIF
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMA_PARPJ
Sequence: MSTSRQQQGRHQGHIARKRFGQNFLVDMGVIDSIVDVIRPQRGERMVEIGPGLGALTEPLIERLATPEAPLHAVELDRDLIGRLKTKFGGLLELHAGDALAFDFGSLAAPGEKASLRIVGNLPYNISSPLLFHLTSFAHRVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVIDKQLDVPPEAFNPPPKVDSAIVRMIPYELHELAPVDERVLGEVVTAAFSQRRKMLRNTLAAYRDSVDFEALGFDLQRRAEDVPVDEYVRVAQIVAAKA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSX2_DANRE
Sequence: MTGKDGAVLSESLNKSKSLCATENGGNNNPHLSKSSITHPPKCTGFGIQEILGLNKEPSSAPRSTLDSFPAGAHLLASRSMLGPAGVGVGVGMGLIGPGGIPSFYSQPAFLEVLSDAQNVHLQPLSRTVGPLEHNQSASSDSDDVSSSERKMSKSSLSQSKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPVQDGFPTTSCFSKHEYPPFFAESILKSAKDGIMDSCAPWLLGMHKKSLETAGHQSNEKSDVTQTPTNPKPDEAEAEERRTESPMSKEELRENSIAALRAKAQEHSAKVLGTVSSERLEHNMETTATEEKSSEQIDAKEEEKSS
What is the function of this protein?
Acts as a transcriptional regulator (By similarity).  Mediates the differentiation of V2a interneurons (By similarity).  Plays a role in eye development and organization of the neuroretina (PubMed:9203137, PubMed:17919464).
What are the official names of this protein?
Visual system homeobox 2, Ceh-10 homeodomain-containing homolog, Homeobox protein ALX, Homeobox protein CHX10, Transcription factor VSX2.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VSPF1_CALRH
Sequence: VIGGDECNINEHRFLVAVYEGTNWTFICGGVLIHPEWVITAEHCARRRMNLVFGMHRKSEKFDDEQERYPKKRYFIRCNKTRTSWDEDIMLIRLNKPVNNSEHIAPLSLPSNPPIVGSDCRVMGWGSINRRIDVLSDEPRCANINLHNFTMCHGLFRKMPKKGRVLCAGDLRGRRDSCNSDSGGPLICNEELHGIVARGPNPCAQPNKPALYTSIYDYRDWVNNVIAGNATCSP
What is the function of this protein?
Thrombin-like snake venom serine protease that acts as an anticoagulant.  It cleaves fibrinogen (FGA) to split off the A-fibrinopeptides (A, AY and AP), but not the B-fibrinopeptide.  The resulting fibrin polymers are imperfectly formed and much smaller in size (1 to 2 um long) than the fibrin polymers produced by the action of thrombin.  These ancrod-induced microthrombi are friable, unstable, urea-soluble and have significantly degraded alpha chains.  They do not cross-link to form thrombi.  They are markedly susceptible to digestion by plasmin and are rapidly removed from circulation by either reticuloendothelial phagocytosis or normal fibrinolysis, or both.  Anticoagulation through the removal of fibrinogen from the blood is rapid, occurring within hours following its administration.  It does not activate plasminogen and does not degrade preformed, fully cross-linked thrombin fibrin.  It also reduces the level of plasminogen activator inhibitor (PAI) and may stimulate the release of tissue plasminogen activator (PLAT) from the endothelium.  The profibrinolytic effect of these 2 actions appears to be limited to local microthrombus degradation.
What are the official names of this protein?
Thrombin-like enzyme ancrod, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP, Venombin A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DNLJ_ECO7I
Sequence: MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKINSLAQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPVVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LYS1_ASHGO
Sequence: MSAILHLRAETKPMEARAALTPTTVRTLVSHGFKIYVEESAQSVFEAAEYAAAGAEVVATGSWRGAPRERIIVGLKELPEEDTFPLEHTHIQFAHCYKNQSGWREVLGRFQSGGGLLYDLEFLQDDRGRRVAAFGYYAGFAGAALGLRDWAWKQTHTDAEDLPAVAPYENEQALVSEVAAACEEAYKKGARKPRVLVIGALGRCGSGAVELLRQCGLHDKHIIRWDIAETARGGPFPEIAAADIFINCIYLSQPIAPFINMELLDRPDRKLRTIVDVSADTTNPHNPVPVYNVATVFSSPTVVVPTSQGPKLSVISIDHLPSLLPREASEAFASDLLPSLLQLPERDTAPVWLRAKELFQQHCERLSKEARL
What is the function of this protein?
Catalyzes the NAD(+)-dependent cleavage of saccharopine to L-lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis.
What are the official names of this protein?
Saccharopine dehydrogenase [NAD(+), L-lysine-forming], SDH, Lysine--2-oxoglutarate reductase.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: NAGD_STAEQ
Sequence: MKHYQAYLIDLDGTMYKGTEEIDGAAQFIDYLNNNRIPHLYVTNNSTKTPVQVTEKLREMHIDAKPDEVVTSALATADYISEQHPNATVYMIGGHGLKTALTDAGLSIKNDEHVDYVVIGLDEKVTYEKLSIATLAVRNGAKFISTNPDVSIPKERGFLPGNGAITSVVSVSTGIQPEFIGKPETIIMSKSLDILGLEKSEVAMVGDLYDTDIMSGINVGIDTIHVQTGVSTYEDIQSKEIPPTYSFKDLNVAIAELEK
What is the function of this protein?
Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
What are the official names of this protein?
Acid sugar phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. NagD family.
Protein: RL30_ECOLI
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30, Large ribosomal subunit protein uL30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: DJC16_ORYSJ
Sequence: MVAMARWPWRVLLPLLLLHSSPVFFVFAQEGQDNDPSTLFKRALEMMNLRKYDGSLGLLNAVLEVEPNHSEAYRQRASVLRHKCRYKEAEGDYSKYLELKPGSSSVEKELSQLLQAQNALESAYGQFESHDFSKVLDYINKIVLVFSPDCLKAKLLKAKALLALKDYSTVISETGFILKEDEDNLDALLLRGRAYYYLADHDVASRHYQKGLRLDPEHSELKKAYFGLKNLVKKTKSAEDNAAKGKLRVSAEDYKASLAMDPDHTSYNVHLYLGLCKVLVKLGRGKEAISSCTEALNIDGELVDALTQRGEAKLLTEDWEGAVQDLKEAAQKSPQDMGIREALMRAEKQLKLSKRKDWYKILGISKTASAAEIKRAYKKLALQWHPDKNVDKREEAENMFREIAAAYEVLGDEDKRVRYDRGEDLDEMNMGGGGGGGFNPFGGGGQQYTFHYDGGFHGGGGFPGGGFPGGFQFNFG
What is the function of this protein?
May play a role in protein folding in the endoplasmic reticulum.
What are the official names of this protein?
DnaJ protein P58IPK homolog A, OsP58A, Chaperone protein dnaJ C16, OsDjC16.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Note=Localizes to the endoplasmic reticulum (ER) and to punctae around the ER.
Protein: KDPA_METRJ
Sequence: MTLNGWIQIALYGAIVLALVKPLGSYMTRVFTGERTFLSPVLGPIERGLYRVSGIDDRQEQHWLAYTGAVILFHVLGFAVLYAILRLQAVLPLNPADQTAVAPDLAFNTSTSFITNTNWQSYGGETTLSYLSQMLGLTHQNFLSAATGIAVAVALIRGFARASSGTIGSFWVDVTRATLYVLLPICVPYTLFLVWQGIPQTLGAYADATTLEGAKQTIALGPVASQVAIKMLGTNGGGFFNANAAHPFENPTALSNLVQMVSIFAIGAALTNVFGRMVGDERQGWAILGAMGILFLAGVLVTYWAEAHGSSVLNSFGLTGGNMEGKETRFGIAASALFAVITTAASCGAVNAMHDSFTALGGLIPLLNMQLGEIIIGGVGAGLYGMLIFVIVAIFVAGLMVGRTPEYLGKKIEAKEVKMAMLGILCLPLMMLGFTALATVVPAGLAGPANAGPHGFTEILYAYTSAAANNGSAFGGLTANTLFYNSTLAIGMLVGRFFVKIPVLAIAGSLAAKKTVPASAGTFPTHGGLFVGLLVGVILIIGGLTFFPSLALGPVVEHLAGAAGQTFATGG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MECA_LISIN
Sequence: MEIERINEDTIKFYISYLDLEERGFNQEDVWYDREKSEELFWDMMDELKYEEEFSPEGPLWIQVQALKHGLEVFVTKATIGGKGEDGFDVTLSSPDELAEEKIEKLLEENFNPVKKESLGEDDTLEFILEFRDFEDLISLSRATGLENLVTKLYSYQGKYYLNVEFPENKYDESNIDNAVSILLEYGLESNLTGYMLAEYGKVIFDVPALKQVRKYF
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: NU3C_COFAR
Sequence: MFLLYEYDIFWTFLIISSLIPILAFFISGILAPISKGPEKLSSYESGIEPIGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDILGVSVFIEALIFVLILIVGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GATC_RHIME
Sequence: MSVDLATVKRVARLARIAVSDEEAERMTGELNGILGFVEQLSEVDVDGVEPMTSVMPMKMKKRDDIVADGDKADDIVANAPNSDRNFFLVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: STX17_BOVIN
Sequence: MSEDEEKVKLRRLEPAIQKFTKIVIPTDLERLRKHQINIEKYQRCRVWDKLHEEHINAGRTVQQLRSNIREMEKLCLKVRKDDLGLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQFNDEETFLQPSLTRSMTVGGTFHSTEDEADPQSMTQIYALPEIPRDQNAAESWETLEADLIELSQLVTDFSLLVNSQQEKIDSIEDHVNTAAVNVEEGTKNLGKAAKYKLAALPVAGALIGGVVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRRKQKMMEKLASSCPDLPSQTDKKCS
What is the function of this protein?
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes.  SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.  STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane.  May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (By similarity).
What are the official names of this protein?
Syntaxin-17.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Smooth endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Cytoplasm, cytosol. Mitochondrion membrane; Multi-pass membrane protein. Note=Has a hairpin-like insertion into membranes. Localizes to the completed autophagosome membrane upon cell starvation.