PharMolix/UniProtQA huggingface dataset:
Protein: Y965_XANOM
Sequence: MRGNIAQLMQQAQKMQENLQRAQEELAKLEVTGTAGGGMVNVTLTGAKECRKVRIDPSILSDQEMAEDLIAAAFNDASNKIDAESKDRMGSATAGMQLPPGMKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein XOO0965.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PHB1_MESAU
Sequence: DLQNVNITLRILFRPVASQLPRIYTSIGEDYDERFDAGELITQRQVSDDLTEREFTEAVEAKQVAQQEAERARKLEAAEDIAYQLSR
What is the function of this protein?
In the plasma membrane, cooperates with CD86 to mediate CD86-signaling in B lymphocytes that regulates the level of IgG1 produced through the activation of distal signaling intermediates.  Upon CD40 engagement, required to activate NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation.
What are the official names of this protein?
Prohibitin 1.
What is the protein family that this protein belongs to?
Belongs to the prohibitin family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Nucleus. Cytoplasm. Cell membrane.
Protein: TRMB_STRPZ
Sequence: MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: FB272_ARATH
Sequence: MMNKESFGACLLLTLPEDVFAVISRFLSPSDICNLILCGKSLCALVDSEKTWLVQCEEVKVLPLIELVQWRIGISSYKALCRFLVEVVKPLLGIWVQENPELGNVVYVMPGFLSVVGCRIIPQKVAPLWIQEGQVKWSPVFEIICGFDGSKGFFLHGRDKQGSFLYPGFVMDIEKSCNVLLLEVEPRSEKSSCNEIEREVGDPFGDLDFSDRMNLLDIVTKHVSLRVDEPLTGNLFPTRSKYDEAMMLERRNMLLKMLKFGGNWKHINLEEDEQLCYNHIEIDIKKLLENLGDDIDNMEDIEDQIEVTPRKKSFRRFLRSGIKHILGKFSSSKINSPSSSETRRSNRQSFLSSGNTFCLSLKASCTLMSSYEGWPIMSADNFSLHKLPMKKPLDHDVYAGLWGGTFGWPPGKDIEDESLLLLMLTYGESEEGSERILFGTKILSYFAEHPNGSSMFVVNIDTPSLEPFPFDTDGRDFEHSYTGEGIADGYGFRYPGSKPGSLFVSSNDLLAFVWQGTEDVITLQRINLGEILKKSLGSCVSPLLPTKNFTYTKRSYSNVFAKSSTYSSSSE
What are the official names of this protein?
Putative F-box protein At5g39460.
Protein: BIOF_SALG2
Sequence: MSWQQRVDDALTARRATDTLRRRYVVSQGAGRWLVANGRQYLNFSSNDYLGLSQHPQIIRAWQQAATRFGVGSGGSGHISGYSVAHQALEEELAQWLGYPRALLFISGFAANQAVITALMKKNDRIVADRLSHASLLEAANLSPAQLRRFIHNDTQHLSRLLQSPCVGQQLVVTEGVYSMDGDSAPLAEIQHIARRHHAWLLVDDAHGIGVTGDEGRGTCWQRGVKPELLVVTFGKGFGVSGAAVLCSESVADYLLQFARHLVYSTSMPPAQAQALSASLAVIRSDEGRERREKLAALVQRFRAGVNASRFTLLNAHSAIQPLIVGDNSRALRLAEALRQQGCWATAIRPPTVPVGTARLRLTLTQAHEACDIDRLLEVLHGAGE
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: PNP_CYTH3
Sequence: MSYPGLTIINKTITLPDGREIQIETGKLAKQADGSAVVKLGNAMILATVVSAKEAKPGVDFMPLSVDYQEKFASNGKIPGGFLKRESRLSDYEILISRLVDRAMRPLFPEDFHADTQVAITLISADADVLPDALACLAAQAAMSVSDIPFNGPVSEVRVISLNGEFIINPKPAQIEKAELELIVAASYDNVIMVEGEMSEVSEELMLNAIKVAHDAIRTQCIVLKELESAAGKTEKRTYSHEVNDWDLKKKINDAVYQQVYEVAKLGNANKNTRAEGFKAVKKAYIESLPADHTEDLTLIGKYYHDVEKDAVRNLILDERKRLDGRSLEQIRPIWSEVGYLPSAHGSAIFTRGETQSLTTVTFGTRLDEQMIDSAMFSGNNKLMLHYNFPGFSTGEVKPNRGPGRREVGHGNLAYRAIKKVMPPEIENPYTIRIVSDILESNGSSSMATVCAGTLALMDAGIKIKAPVSGIAMGLITDTKTGRWAVLSDILGDEDHLGDMDFKVTGTEKGITACQMDIKVDGLSYDILSQALQQANRGRLHILSEMKKTLATPREDLKPHAPRMIMIQIPKELIGAVIGPGGKIIQEIQKTSGATVNIEEKDNAGWVSIFSKDKTALDSALSQIKGIVTLPEVGEVYEGKVKSITAFGAFVEFLPGKDGLLHISEIKWERLDTMEGVLEVGETVKVKLVEVDKKTGKYRLSRKVLIPKPEQQATSNS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYG_STAAW
Sequence: MAKDMDTIVSLAKHRGFVFPGSDIYGGLSNTWDYGPLGVELKNNVKKAWWQKFITQSPFNVGIDAAILMNPKVWEASGHLNNFNDPMIDNKDSKIRYRADKLIEDYMQDVKGDENFIADGLSFEQMKKIIDDEGIVCPVSKTANWTEIRQFNLMFKTFQGVTEDSTNEIFLRPETAQGIFVNYKNVQRSMRKKLPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFCKPGEEIEWQNYWKTFASDWLTSLNMSSENMRLRDHDEDELSHYSNATTDIEYKFPFGWGELWGIASRTDFDLRKHAEHSGEDFRYHDPETNEKYIPYCIEPSLGADRVTLAFLCDAYDEEGVEGSKDARTVLHFHPALAPYKAAILPLSKKLSGEAIKIFEQLSSKFSIDFDESQSIGKRYRRQDEIGTPYCVTFDFDSLEDNQVTVRDRDSMEQVRMPISELEAFLTEKTKF
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_BART1
Sequence: MKLNELRDCEGATKNRKRIGRGIGSGTGKTGGRGVKGQKSRSGVSLNGFEGGQMPIYRRLPKRGFKNFFSKIYNEVSLGRIQLAVDTGKLNIEKPVDMIALKEAGIIRREKDGVRLLSDGDLKAKITFHVSGASQAARVKVEKVGGQVISPEVVG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: DTD_STAS1
Sequence: MRIVVQRVKHASVTNDSVDNKINKGYCLLVGVGKSSTEADIATLAKKIVNARLFEDADGKLNLNLQQVEGEILSISQFTLYADVRKGNRPGFTQSMSPDCANELYEQFNDTLRSYGINVLTGEFGTDMLVDIANDGPVTIIYESQDGKII
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_GLAP5
Sequence: MSFTVIIPARYSSTRLPHKPLLDIAGKPMIQHVWEKAQQSGATRVIVATDHPEIEQVVTRFGGEVCLTSDKHNSGTERLAEVIEKMAIADDEIIVNIQGDEPLIPPLIVAQVAENLDKHQVNMATLAVKLTTREELFNPNVVKTLTDKNGMALYFSRATIPFGRDYFPQCDDAFVQQQNYLRHIGIYAYRAGFVKQYVAWEPTALEQLESLEQLRALWYGEKIHLDLAKEAPQVGVDTAEDLERVRQILNILCSQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAX_HTL1L
Sequence: MAHFPGFGQSLLYGYPVYVFGDCVQGDWCPISGGLCSARLHRHALLATCPEHQITDPIDGRVIGSALQFLIPRLPSFPTQRTSKTLKVLTPPTTHTTPNIPPSFFQAVRQHSPFRNGCMEPTLGQQLPSLSFPDPGLRPQNLYTLWGSSVVCMYLYQLSPPITWPLLPQVIFCHPGQLGAFLTNVPYKRMEELLYKIFLNTGALIILPEGCLPTTLFQPIRAPATLTAWQNGLLPFQSTLTTPGLIWTFSDGTPMISGPCPKDGQPSLVLQSSSFIFHKFQTKAYHPSVLLSHGLIQYSSFHSLHLPFEEYTNIPISLLFNKREADDTDYGPRIPPGGLEPPSEKHFHETEV
What is the function of this protein?
Transcriptional activator that activates both the viral long terminal repeat (LTR) and cellular promoters via activation of CREB, NF-kappa-B, SRF and AP-1 pathways.  Binds to three 21 bp repeat elements located within the LTRs, referred to as Tax-responsive elements (TRE).  Binding to TRE requires the interaction with CREB1 and CREBBP.  Also induces chromatin remodeling of proviral LTR-mediated gene expression by recruiting the histone acetyl transferases CREBBP and EP300 to the chromatin, which results in histone acetylation.  Via its interaction with IKK regulatory subunit IKBKG, Tax-1 persistently stimulates I-kappa-B kinase (IKK), resulting in constitutive activation of the transcription factor NF-kappa-B.  Induction of the nuclear expression of members of the NFkB family of transcription factors, which leads to up-regulated expression of many gene promoters containing NFkB motifs.  These genes include those encoding IL2, IL15, IL2RA and IL15RA, leading to autocrine IL2/IL2RA and IL15/IL15RA loops.  The resulting T-cell proliferation leads to malignant transformation and to the development of adult T-cell leukemia (ATL).  IL13, known to be linked to leukemogenesis, is also up-regulated by Tax-1.  Interaction with PDZ domain-containing proteins induce IL2-independent growth, which may be a factor in multi-step leukemogenesis.  Inhibits the action of at least three cellular tumor suppressors p53/TP53, RB1 and DLG1, and suppresses their abilities to dictate apoptosis in primary cells.  Required for viral replication (By similarity).
What are the official names of this protein?
Protein Tax-1, Protein X-LOR, Trans-activating transcriptional regulatory protein of HTLV-1.
What is the protein family that this protein belongs to?
Belongs to the deltaretrovirus Tax protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Shuttles from the nucleus to the cytoplasm. Found predominantly in the nucleus, where it is equally distributed between the nucleoplasm and the nuclear matrix (By similarity).
Protein: BTAF_BRUSU
Sequence: MKLPPVFVFELVENQGLANIALIRPRVIAPDNNLRPGGIVSGIAGLLTLGQENRNLISENRQVINNNTTAIGQNSDRIDANAKGVADNRAAIGQNSGRIDANAKGVADNKAAIGRNSGRIDANAKGVADNKTAIGRNSGRIDTNAKGVADNRAAISQNRGRINANAAGVASNRAAIRQNSAAISALGQRVDGLQGQINSARKEARAGAANAAALSGLRYDNRPGKVSIATGVGGFKGSTALAAGIGYTSKNENARYNVSVAYNEAGTSWNAGASFTLN
What is the function of this protein?
Participates in bacterial attachment to several surfaces, including various extracellular matrix (ECM) components and a hydrophobic abiotic surface.  Involved in adhesion to host epithelial cells and is required for full virulence in mice.  Also implicated in the resistance to porcine serum.
What are the official names of this protein?
Autotransporter adhesin BtaF, Brucella trimeric autotransporter, Type 5 secretion system autotransporter BtaF.
What is the protein family that this protein belongs to?
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
What are the subcellular locations of this protein?
Cell surface. Cell outer membrane. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface (By similarity). Localizes at the new cell pole generated after cell division (PubMed:24236157).
Protein: PYRF_BAUCH
Sequence: MTYDVLSAIASPIIVALDYTNISKALAFVDLISPLYCRLKIGKIMFTRFGPELIIKLQQRGFDIFLDLKYHDIPNTVAGAVSAAADLGVWMISLHAIGGEKMMAAACNALSNFGLGVPKLIAVTVLTSLSDEDLQIIGIPSTASDFAIRLAILAKNCGLDGVVCSAQEAEHIKNICGHHFTIVTPGIRLATDELGDQCRIMTVHQAQQAGVNYMVIGRPITQATKPNCRLVEILNSLKITANSVALSSN
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RBL_PINKO
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEENQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAINKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRMSGGDHVHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGVYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEVIREACKWSPELAAACEIWKEIKFEFDVIDRL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DDI3_YEAST
Sequence: MSQYGFVRVPREVEKAIPVVNAPRPRAVVPPPNSETARLVREYAAKELTAPVLNHSLRVFQYSVAIIRDQFPAWDLDQEVLYVTCLLHDIATTDKNMRATKMSFEYYGGILSRELVFNATGGNQDYADAVTEAIIRHQDLTGTGYITTLGLILQIATTLDNVGSNTDLIHIDTVSAINEQFPRLHWLSCFATVVDTENSRKPWGHTSSLGDDFSKKVICNTFGYN
What is the function of this protein?
Cyanamide hydratase involved in the detoxification and/or utilization of cyanamide, a toxic nitrile compound distributed widely in the environment.
What are the official names of this protein?
Cyanamide hydratase DDI3, CAH, DNA damage-inducible protein 3.
What is the protein family that this protein belongs to?
Belongs to the cyanamide dehydrase family.
Protein: MUTS2_STAA3
Sequence: MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRSKISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEDRTVYLPKAYHPLLNRETVVANTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: RL25_METS4
Sequence: MSAVKPLEAVARDRVGKGAARAVRRQGRVPAVIYGGGQSPQSISLDANQTHHLIYGGGFLSTVFEIAVDGRTIRAIPRDYQLDPVKDTPLHVDFLRVVSGQTIEVEVPVHFVNQDAAPGLKQKSGTLNVVLHTITLAVSPDAIPDAVNVDLTGKDIGDTVHVSDLVLPTGASLALAPSETVATLVPPTKLGADVEAEEAAVAEAARAGSAAEAAKEG
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: YMFD_ECOLI
Sequence: MVLALNYNMHGVNIRSENAAKPHTMPSRYLCEYIRSIEKNGHALDFGCGKLRYSDELISKFDEVTFLDSKRQLEREQIIRGIKTKIIDYVPRYYKNANTVAFEDVDKIIGGYDFILCSNVLSAVPCRDTIDKIVLSIKRLLKSGGETLIVNQYKSSYFKKYETGRKHLYGYIYKNSKSVSYYGLLDELAVQEICSSHGLEILKSWSKAGSSYVTVGSCNAI
What are the official names of this protein?
Uncharacterized protein YmfD.
Protein: IAAS_WHEAT
Sequence: DPPPVHDTDGNELRADANYYVLPANRAHGGGLTMAPGHGRRCPLFVSQEADGQRDGLPVRIAPHGGAPSDKIIRLSTDVRISFRAYTTCVQSTEWHIDSELVSGRRHVITGPVRDPSPSGRENAFRIEKYSGAEVHEYKLMACGDSCQDLGVFRDLKGGAWFLGATEPYHVVVFKKAPPA
What is the function of this protein?
Inhibitor of endogenous alpha-amylase (wheat also produces an exogenous inhibitor which inactivates alpha-amylase from animal and insect origin).  This inhibitor can also inhibit subtilisin.
What are the official names of this protein?
Endogenous alpha-amylase/subtilisin inhibitor, WASI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: RTX2C_ACTSU
Sequence: MMLKNDFNVLGQIAWLWANSPMHRNWSVSLLMKNVIPAIENDQYLLLVDDGFPIAYCSWAKLTLESEARYVKDTNSLKIDDWNAGDRIWIIDWIAPFGDSSLLYKHMRQRFPYDIGRAIRIYPSKKDTGKIIYLKGGKITKKVAEKTFLQYEQELITALQ
What is the function of this protein?
Protein-lysine acyltransferase that catalyzes fatty acylation of the protoxin, thereby converting it to the active toxin.
What are the official names of this protein?
RTX-II toxin-activating lysine-acyltransferase ApxIIC, APX-IIC, Cytolysin IIC, CLY-IIC, HLY-IIC, RTX-II toxin determinant C, Toxin RTX-II-activating protein C.
What is the protein family that this protein belongs to?
Belongs to the RTX toxin acyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYM_XENLA
Sequence: MGANSSTIKELSENEYLKKLSGMDSISENEPFWNQLLSFTLSTPTNSADSKLLEEGTLSICKSLIENNPRTGNLGALIRVFLSRTKELKISAECQNQLFIWQAHNALFIICCLIKVFTSQVSEEELLLHFTYRATDPGNYEADTEDLFEELLFCLIQLIVEIPLLDLTYSILLEAVTALIVLLSYQLFHKDILHESPIHKHLMNGRCLPYTSRLVKTLLYNFIRQEKSPPPGSHIFPQQQDGGGLLYGLASGVASGIWTVLTLGGVGSKPTPQQEQSSPLANQSLLLLLVLSNLTDSPDCPNPFRQSVTFFKNTQDSSVSPTPNPHSFQINFNSLYTSLCEQQKSDQATLLLYTLLHQNSNVRTYVLARSDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYTERVLTEISLGSLLILVVIRTIQFNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLGSDESPLPDYAQDLNVIEEVIRMMLEIINSCLTNSLHHNPNMVYALLYKRELFEQFRSHPSFQDIMQNIDMVISFFSLRLEQAGADLSVERVLEVIKQGAVALPKDRLRKFPELKFKYVEEEQPEEFFIPYVWSLVYHSGVGLYWNPQDVQLFTMDSG
What is the function of this protein?
Necessary for correct organization of Golgi apparatus.
What are the official names of this protein?
Dymeclin.
What is the protein family that this protein belongs to?
Belongs to the dymeclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Note=Sequence analysis programs predict 3 transmembrane regions. However, it has been shown in human that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol (By similarity).
Protein: ADD_CLOPE
Sequence: MNLLNLPKIELHCHLDGSLRVETAIELAKKEGVKLDSYEYDKVKELLVIPKECNSLEDYLNRFALPVKLLQRAENLERVAFELMEDASKENVKYIEIRFAPLLHLEKGMTQKEVIESVIKGIRKAEELYDIKGNLILSCLRHHSIDSVYEVIEEGKNFIGKGVVAIDLAGGELEGFVKPYEEVMKLARESGFRVTIHAGETGYGKNVRDAIELLGAERIGHGLFIFNDEEAYNLVKEKGVTLEMCPKSNIDTKGVNKYEDHPIYKYHKDNIRVNLSTDNRTVSNINLTEEFENVHKTFNIDFEDYKKIYLNSVEASFCSEELKEKLKLSIII
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: CSN12_YEAST
Sequence: MDVDIGCYFEEKRYDDKLLDFIRYDVKTPKKTKYILQRPTATDEESVRLQRFYQLGVDLKLKYSKRRSLKKQGRIKNATEELLRLANEQLKLFNRIVERETNWIIYPLWVMAKQLIRLANESSELNKDSIEECGRTIHRSFTICLNDRNPRLNENKKIGCYMFANLEFSIYHRLSNKDMIKNLVKVLESRVNARDIPPLNKSLAMEHKSQVVLYNYYLGQYYGCLENDHERGFFHLNEALLQCPMLYVESTGKFVLQGQMEKIMILLVPLALLTKRLYPHWDHPVIAGVITRSKRLSQVYPTLVRSVISGNLSLYEATAASHERFFLSQGLHVVITLLREVVFTRLVQRCWQWGNDRKSIMPLKILLATKQHDSSANEDEEEQLDALECRLASAIASGLLRAYLSHSNRCIVFSKKEPFPHSK
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.  The CSN complex is involved in the regulation of the mating pheromone response.  CSN12 forms a complex with THP3 that is recruited to transcribed genes and required for transcription elongation.
What are the official names of this protein?
Cop9 signalosome complex subunit 12.
What is the protein family that this protein belongs to?
Belongs to the CSN12 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRUA_CERS4
Sequence: MPRYALRIEYDGGPFAGWQRQAAQASVQGAIETALGRLEPGPHTIAAAGRTDTGVHASGQVAHCDLVREWDPFRLAGALNAHLKPLPVAIVAAARVPEEFHARFSAVERRYLFRLLARRAPEVHDRGRVWRVPHPLDPEAMRAGAAHLVGRHDFTTFRAAGCQAASPVKTLDALTLETVEGMNGTEYRFHLRARSFLHNQVRSIVGTLERVGAGAWTPDQVREALDARDRAACGPVSPPQGLYLTGVGYPADPFA
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PSIE_YERPG
Sequence: MAKNSRSQWIAKNLQRLLNVGLIMLAAILVVFLVKETIHLGKVLFLSNQETSSYMLIEGIVIYFLYFEFIALIVKYFESGYHFPLRYFIYIGITAIIRLIIVDHENPIDTLIYSGSILVLVVTLYLANTERLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_JANMA
Sequence: MQLNPSEISELIKSRIQGLGDTAEIRNQGTVISVSDGICRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYEHISEGDTVKCTGRILEVPIGPELCGRVVNALGQPIDGKGPINTKLTTPIEKIAPGVIARQSVDQPMQTGIKAIDAMVPIGRGQRELIIGDRQTGKTAVAIDAIINQKGQGVTCIYVAIGQKASSIKNIVRALEQHGAMEYTIVVAATASESAAMQFVSAYSGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSLFNSGVRPAINAGISVSRVGGAAQTKVIKGLSGGIRTDLAQYRELAAFAQFASDLDASTRKQLDRGARVTELLKQAQYAPLSTSLMAVSLFAVNKGYFDDLEVKQVLAFESGLHGFMKSSHAALLQKIEDTKKLEKDDEAVLAAAIADFKKSF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UL22A_HCMVM
Sequence: MARRLWILSLLAVTLTVALAAPSQKSKRSVTVEQPSTSTNSDGNTTPSKNVTLSQGGSTTDGDEDYSGGDYDVLITDTDGGNHQQPQEKTDEHKGEHTKENEKTQ
What are the official names of this protein?
Glycoprotein UL22A.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 UL22A protein family.
What are the subcellular locations of this protein?
Virion.
Protein: TX21D_RHYMT
Sequence: MKDSYISIVIAYLMVTFILVSSMPIEGEKRELGPHRLPCPPKLNDENYCFNGKCVHLVAQDEPGKPYYSCICDEFYIGERCGTLDLTNPGYFLKGQSSTQSSI
What is the function of this protein?
Ant peptide with probable defensive activity which acts as a potent agonist of the mammalian epidermal growth factor receptor (EGFR).  Mimics, both structurally and functionally, vertebrate epidermal growth factor (EGF) peptide hormones.  In vivo, intraplantar injection in mice causes long-lasting (several days) hypersensitivity of the injected paw to both mechanical and thermal stimuli.  Its long-lasting effect is unusual for venom toxins whose effects are usually immediate.  One possible explanation is that it would reduce the duration of a nest attack, discourage future attacks, or enhance the actions of subsequent exposure to other pain-inducing venom peptides.
What are the official names of this protein?
OMEGA-ectatommitoxin(02)-Rm1d, ECTX2-Rm1d, OMEGA-ECTX2-Rm1d.
What is the protein family that this protein belongs to?
Belongs to the EGF domain peptide family.