PharMolix/UniProtQA huggingface dataset:
Protein: CTAA_BACAC
Sequence: MQRFIKWLAVITSLDLLIVLLGGALVTKTGSGQGCGKSWPLCNGEFVPSNLSMETIIELSHRLTSGSAGILVTLLCILSWKYYKHVRETKTLAILSFVFLVAQALMGAAAVVWGQMPAVLAIHFGISLISFASVILLTCLIFEIDQKFDARSLIMDKKMKFHIYGVTIYCYLVVYTGALVRHERASLACPDFPLCSKNRPMPTQLHEWVQMGHRLAAMLIFVWILYAMILAIRHYKQQPVVYWGWIISFILVTLQAIVGILVVFTNASLAMALLHSLFISCLFAVLCYLVMLGTRSKVNAKEAASTSKQTK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNHG2_STAAW
Sequence: MEITKEIFSLIAAVMLLLGSFIALISAIGIVKFQDVFLRSHAATKSSTLSVLLTLIGVLIYFIVNTGFFSVRLLLSLVFINLTSPVGMHLVARAAYRNGAYMYRKNDAHTHASILLSSNEQNSTEALQLRAEKREEHRKKWYQND
What are the official names of this protein?
Putative antiporter subunit mnhG2, Mrp complex subunit G2, Putative NADH-ubiquinone oxidoreductase subunit mnhF2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HGPRT_STAAC
Sequence: MHNDLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGSAMFMSDLIKRIDTHLSIDFMDVSSYHGGTESTGEVQIIKDLGSSIENKDVLIIEDILETGTTLKSITELLQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYRELYRNLPYIGTLKPEVYSN
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15E_THEGJ
Sequence: MGMYKYIREAWKSPKKSYVGELLKKRMIKWRREPVVVRIERPTRLDRARSLGYQAKQGYVVVRVRVRRGGRKRPRWKGGRKPSKMGMVKYSPKKSLQWIAEEKAARKFPNLEVLNSYWVGEDGMYKWFEVIMVDPHHPVIKSDPKIAWITGKAHKGRVFRGLTSAGKKGRGLRNKGKGAEKVRPSVRANKGKTK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: RAGP1_DROME
Sequence: MSTFNFASMAAQLGQEQGISFENKVLSWNTAADVQDVVDALNKQTTVHYLNLDGNTLGVEAAKAIGEGLKRHPEFRKALWKNMFTGRLISEIPEALKHLGAALIVAGAKLTVLDLSDNALGPNGMRGLEELLRSPVCYSLQELLLCNCGLGPEGGSMLSRALIDLHANANKAGFPLQLRVFIGSRNRLEDAGATEMATAFQTLKTFEEIVLEQNSIYIEGVEALAESFKHNPHLRVLNMNDNTLKSEGAEKIAEALPFLPLLREMSFGDCLIKTNGAYHFGEALERGNERLEVIDLGFNEINSDGGLVLVNAMGNKPKLRILNLDGNSFGEEGSEKIISEMSKLPTAAALQPFQHQEEEDLEDEYQADKQDADYEEEEEVHEHANDTTEEADEDSEGDEDDEEDEGDEEYSNVAEETAYVTTNAYTTKLFNDTTNSMASETFAVANKTISQKCTPEKFCLSQKPCSQEDFDSLDMDNKLEALQSIVNQFTGDNHLLLLVFTTLKCAHLSQSSKAALDLAVSLYQATFDYAIKTKQETRVLNYVLMQLRLLPCKEVFHSDYDVKNCRFALREALKQPTFANDNIKNSFKTFLEGAES
What is the function of this protein?
GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state (By similarity).  Trans-acting factor necessary for meiotic distortion (PubMed:10073941).  Distortion is only seen in individuals that carry the RanGAP tandem duplication and express a RanGAP truncated protein.  Binding of truncated RanGAP product to the Responder(RSP) locus initiates events that lead to sperm dysfunction (PubMed:10073941).  During oogenesis, plays a role in the biogenesis of annulate lamellae containing nuclear pore complex components (PubMed:31626769).
What are the official names of this protein?
Ran GTPase-activating protein, RanGAP, Protein segregation distorter.
What is the protein family that this protein belongs to?
Belongs to the RNA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Association to cytoplasmic side of the nuclear pore complex is promoted by Nup214 (PubMed:17032737). Co-localizes with Nup358/RanBP2 to annulate lamellae (PubMed:31626769).
Protein: EF1G_CAEEL
Sequence: MTGKLYGNKDNFRTQKVLIAAKLANKTVTLAGDAAPADKFPLGVTPAFEGDALLFGAESIGLHLTGTSANAETVQWLQFAEGYLLPAVLGYVLPSVSAANFDKKTVEQYKNELNGQLQVLDRVLVKKTYLVGERLSLADVSVALDLLPAFQYVLDANARKSIVNVTRWFRTVVNQPAVKEVLGEVSLASSVAQFNQAKFTELSAKVAKSAPKAEKPKKEAKPAAAAAQPEDDEPKEEKSKDPFQDMPKGTFVLDNFKRSYSNEDTATKAIPHFWENFDADNWSIWKCEYKYPEDLTLAFMSCNLINGMYQRLEKLKKNAFASMILFGTDNNSTISGIWVWKGDKLAFELSPDWQVDYESYTWTKLDAKSDATKKEVNEYLMWEGDFGGKKFNQGKIFK
What is the function of this protein?
Probably plays a role in anchoring the complex to other cellular components.
What are the official names of this protein?
Probable elongation factor 1-gamma, EF-1-gamma, eEF-1B gamma.
Protein: MURG_BACLD
Sequence: MRIVVSGGGTGGHIYPALAFIKEVKRHHEDVEFLYIGTEKGLEKNIVEREGIPFKAIEITGFKRKLSFENVKTVMRFLKGVKECKEELKRFKPDAVIGTGGYVCGPVVYAASKLGIPTIIHEQNSLPGLTNKFLSKYVDKVAICFDEAKTHFPAEKVVFTGNPRASEVVSIKGGRSLTALGLAEGKKTVLIFGGSRGAAPINEAVIAMQNELKKRDYQVLYVTGEVHYDKVTAALEKEGAAPNMVVQPFLHQMPEYLKAFDVVVGRAGATTIAEITALGIPSVLIPSPYVTANHQEVNARSLGEQNAAVVLKESELNGDRLIQAIDHILQDEKTLEEMKIRAKSLGVPDAAERLYNVLKELKHHAK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SSP32_CAEEL
Sequence: MLTIEPPSATFPASGGSSTHTITSVNESRMAFKVKSSNNEHYRVRPVYGFVEARGKMKFEIIRLEGPVKDDKIMLQYAEVPADETDAQAPFKAGAQQGDVTILLKTN
What are the official names of this protein?
Sperm-specific class P protein 32.
Protein: RPOC_MYCSS
Sequence: MLDVNFFDELRIGLATADDIRQWSYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITDVNDEMRHNELSTLEAEMVVEKKAVEDQRDADLEARAQKLEADLAELEAEGAKSDVRRKVRDGGEREMRQLRDRAQRELDRLDEIWTTFTKLAPKQLIVDEVLYRELVDRYGEYFTGAMGAESIKKLIENFDIEAEAENLRETIRSGKGQKKLRALKRLKVVAAFQTNRNSPMGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRPQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGKPLAMPRLDMVTGLYFLTTMIEGDKGEYRPAATDQPEEGVYSSPAEAIMAMDRGALSVRAKIKVRLTQLRPPAALEAELFENGWKPGLAWTAETTLGRVMFNELLPISYPFINEQMHKKVQARIINDLAERFPMIVVAQTVDKLKDAGFHWATRSGVTVSMADVLVPPQKQEILDRYEAEADGIERKYQRGALNHKERNDSLVKIWQDATEEVGKALEEHYPADNPIITIVKSGATGNFTQTRTLAGMKGLVTNPKGEFIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCETERGINVTLAERQPDGSLIRDPHVETSAFARTLATDAVDADGNVVIERGHDLGDPAIDKLLAAGIDHVKVRSVLTCASATGVCAMCYGRSMATGKLVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGEDITGGLPRVQELFEARVPRNKAPIADVSGRVQLEEGERFYKITIVPDDGGEEVVYDKLSKRQRLRVIKHEDGSEGVLSDGDHVEVGDQLMEGSADPHEVLRVQGPREVQIHLVHEVQEVYRAQGVSIHDKHIEVIVRQMLRRVTIIDSGATEFLPGSLTERAEFESENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLQGLKENVIIGKLIPAGTGINRYRNIQVQPTEEARAAAYTIPSYEDQYYSPDFGQATGAAVPLDDYGYSDYR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ATPG_FLAPJ
Sequence: MANLKEIRNRITSVSSTMQITSAMKMVSAAKLKKAQDAITAMRPYAEKLTELLQNLSATLDGDAGGEFTKQREIKKVLVVAITSNRGLCGAFNTNVIKEVKNRADFYAGKQVDVFAIGKKGNDVLSKTLSVIDNQSSVFDALTFDNVAKIAQMLTDKFVAGEYDRIEVIYNQFKNAATQIVQTEQFLPLAPIKSDLPVSTGDYIFEPSKEEIVLTLIPKSLKTQLYKGIRDSFASEHGARMTAMHKATDNATELRDQLKLTYNKARQAAITNEILEIVGGAEALKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CIPKJ_ORYSJ
Sequence: MAATPPSSQHRRPLSSSASAASLAGKPRGGGLLLGRYELGRLLGHGTFAKVYQARSADSGEPVAIKVLDKEKAMRHGLVPHIKREIAILRRVRHPNIVRLFEVMATKSKIYFVMELVRGGELFGRVAKGRLKEDTARRYFQQLVSAVGFCHARGVFHRDLKPENLLVDEHGDLKVSDFGLSAVADQFHPDGLLHTFCGTPSYVAPEVLARRGYDGAKADIWSCGIILFVLMAGYLPFHDQNLMAMYRKIYRGEFRCPRWFSKDLSSLLNRILDTNPETRITVKEVMESRWFQKGFRPVRFYVEDDQVHSLADGDNDMPELEPSEPPPPPPFPPPPPQQDDDGEESGWESDSSVASCPATLSSEERRQRPLGSLTRPASLNAFDIISFSKGFDLSGLFEERGSEVRFISAEPMQTIITKLEEIAKVKSFFVRRKDWRVSIEGTREGLKGPLTIGAEIFELTPSLVVVEVKKKAGDKEEYDDFCNRELKPGMQHLVHHMGSVPNIPSDTE
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting protein kinase 19, OsCIPK19, OsPK4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: PDXB_ALISL
Sequence: MKILIDENMPYAAELFSELGEVIAKSGRTLTADDLIDVDALMIRSVTKVNSELLSKANKLSFVGTATAGMDHVNQALLKNKGVFFTAAPGCNKVGVAEYVLSCVMVLAQQHGFSIFDKTFGIIGAGQVGSYLAQCLDALSIPYLLNDPIKEQEGDTRSFVSLDELLEKSDVISLHTPITRDGNFPTHHLIGQERLLTLRHDQILINAARGPVVDNDALKNRLLIQDGFKAVLDVFEFEPEVDIALLPLLSFATPHIAGYGLEGKARGTTMIFNSFCEFLQREERADPQNLLPVAPIPNVTLNQQWDHSTLHNLIQLVYDVRKDDAVFRKEISTIGAFDNMRKDYWDRREYSAITITGNKDCGLTPLKQLGFTIEEV
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FH17E_MOUSE
Sequence: MAEAPSRMQQNYDWQCEDAINTHIQLCLYASYEYMSMAVYFDRDDVAQENFKRFFLTKSHNCQTSAEMFMHLQNKRGGCSSLQGIARPERDSWHGGFQAMECAFHMEMLINQSLLNMHEVAKEKGDPHLCHFLEQNCLDQQVDILKEMSGYLTNLRQMGAVEHNLAEYLFDKLSLS
What are the official names of this protein?
Ferritin heavy polypeptide-like 17E.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: UVRC_CYAP4
Sequence: MTSPQALQLIKDPDRLESRLKEIPAEPGVYFMRDSQDQILYIGKSKKLRSRVRSYFRKFNELGPRLELMVRQVAEIEFIVTDTEAEALALEANLIKQHQPHFNVLLKDDKKYPYLCITWSEAYPRIFITRKRRAEAKDDRYYGPYTDTHLLRQTLGLVKRIFPLRQRPKPLFKDRPCLNFDIGRCPGVCQQLIASEDYRKTIHKVAMIFQGRTSELIDTLTPQMEAAAENLNFEQAARIRDQINGLKTLGEEQKVSLPDDTVSRDAIALAADEQHACIQLFQIRAGRLVGRLGFVADAQSGPPGAILQRVLEEHYAGADPVEIPAEILVQTELPEAEMLATYLTEYKGRKVTLLVPQRQSKAELIEMVERNAQYELARTQRFSDRNAEAQKDLAELLDLPELPQRIEGYDISHVQGSDAVASRVVFIDGLPAKQHYRHYKIKNPNVTAGHSDDFASLAEVVQRRFRKFIEHPETDRLSDPDWPDLIMIDGGKGQLSAVVNALSGTGLLEDLQIVSLAKQREEIFLPGESLPLNTDPDQPGVQLLRRLRDEAHRFAVSFHRQQRTERMRRSRLDEIPGLGYERQKQLLAAFRSIDYIREASPEQLATVPLIGPRLAQQIYDYFHP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHEA_AGLNE
Sequence: MKSVITTTISARDAAGRFPSRSDLESVQGNIQRSAARLEAAEKISAGHEGVVKEAGDACFAKYTYLKTSGEAGDSQDKVNKCYRDIDHYMRLINYSLVVGGTGPLDEWGIAGAREVYRALNLPASAYIAAFAYTRDRVCVPRDMSAQAAVEFIGALDYVNSLS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
R-phycoerythrin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the periphery of the phycobilisome rod.
Protein: ODPB_DROME
Sequence: MLRTRLIQAASSAQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKKYGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMSAGAVNVPIVFRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDPVVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAELAKKGIEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTFFELDAPVWRCAGVDVPMPYAKTLEAHALPRVQDLVEATLKVLGGKVGKAAAANK
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity).  Might play a role in regulating synapse structure formation at neuromuscular junctions (PubMed:29501567).  Might play a role in maintenance of mitochondrial morphology (PubMed:29501567).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial.
Protein: DPPF_PSEAB
Sequence: METVLTARDLTRHYEVSRGLFKGHAQVRALNGVSFELEAGKTLAVVGESGCGKSTLARALTLIEEPTSGSLKIAGQEVKGASKDQRRQLRRDVQMVFQNPYASLNPRQKIGDQLAEPLLINTALSREERREKVQQMMRQVGLRPEHYQRYPHMFSGGQRQRIALARAMMLQPKVLVADEPTSALDVSIQAQVLNLFMDLQQQFRTAYVFISHNLAVVRHVADDVLVMYLGRPAEMGPADKLYENPLHPYTRALLSATPAIHPDPTKPKIRIQGELPNPLHPPEGCAFHKRCPYATERCRSEVPELRLLDQRQVACHHAEQFLG
What is the function of this protein?
Part of the ABC transporter DppABCDF involved in the uptake of various di/tripeptides (PubMed:25338022).  Is also involved in the uptake of phaseolotoxin, a toxic tripeptide inhibiting the enzyme ornithine carbamoyltransferase (PubMed:25338022).  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Di/tripeptide transport ATP-binding protein DppF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBP48_CHICK
Sequence: MAPRLQLEKAAWRWTETVPPEAVTQEHIEAAYRVGLEPCQRGTCRRNCRGNPNCLVGIGEHVWLGEIDENSFHNIDDPNCERRKKNAFVGLTNLGATCYVNTFLQMWFLNLELRQALYLCSSNEHAAGESIPKDKDYEPQTICEHLQYLFALLQNSKRRYIDPSGFVKALGLDTGQQQDAQEFSKLFMSLLEDTLSKQKNPDVRNIVQKQFCGEYAYVTVCNQCGRESKLVSKFYELELNIQGHKQLTDCITEFLKEEKLEGDNRYFCETCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSELLDMEPFMEQKNGVYVYELSAVLIHRGVSAYSGHYIAHVKDPQTGEWYKFNDEDIEKMEGKKLQLGIEEDLAEPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTREKSLTVEVPAFLQELVERDNCKFEEWCNEMAEMRKQSVARGKIKHEEVKELYQRLPAEAGSPYDFISLEWLQKWLDESTPPKPIDNTACLCSHGKLHPDKICIMKRISEYVADFFYRRYGGGPRLNVKALCKDCVVERCRILRLKNQLNEDYKTVTNLLKITVKGSEGFWVGKASLRSWRQLALEQLNEQDEDAEHSNGKLNGNAPNKDEVNEEKREEEEELNFNEDIVCPHGDLCISENERRVVSKEAWKKLKQYFPKAPEFPSNKECCSQCKILEREGEENEALHKMMASEQKTSLQNLFHDKCRPCLGSWPQETDELYIVSQFFVEEWRKFVRRPTRCSPVSSLGNSALLCPHGGLMFTYASMTKEDSKLIALIWPSEWERIQKLFVVDHVIKITRTRAAGEPESALYSSEPQLCPECRGGLLCQQQRDLREYTQATIYIHKVVDNKKVMKDAAPELNVSSSEAEEEREENKPEGEQDPDFNQSNGGAKRQKLSHQSYISYQKQGIRRSTRHRKVRGEKALLVSANQTLKELKIQIMHAFSVAPFDQNLLIDGKILSDDTATLGSLGIIPESVILLKADEPIADYAAMDDVMQVCMPEEGFKGTGLLGH
What is the function of this protein?
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 48, Deubiquitinating enzyme 48, Ubiquitin thioesterase 48, Ubiquitin-specific-processing protease 48.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RBKTP_CUPPJ
Sequence: MKESGTFFLVVGPSGAGKDSLIDGARATLGNDEYVFARRIITRPSGSPGEDHESVAEAEFAERERNGEFLVTWHAHGLRYGLPQWLVGLLETGKHVVANGSRGVIAMLARQLPRFVVVNVTAPQDVLAQRIAARGRESGDDVMRRVARQAPPMPDGVHCVTVTNDSTLDLGVARFTDALRNGANAGSVPQPASRRHLAAKLDGQPLDEGAYEAILRDAIAGRYTAQELTAFLTAATRSLDDREVVALARARTRFTARIEWDEPIVVDKHSMGGIPGSRITLIVVPIVAAYGLAMPKTSSRAITSAAGTADAMETVARVDLTHDDVRRCVAQARACIAWNGRLNHSVIDDVMNAITRPLGLDSRRWAVASILSKKATAGATHVIVDIPYGPQTKLSARADADALAGLFEEVGKGLGLHVRALVTDGSRPIGRGVGPALEVRDVRQVLENHPDAPMDLREKALRFAGEIIAFDPRVASAAQGMRIATALLDEGSARAAFDRIVATQGIRPDPVAPGAHTHVIVAPAEGRVAAINGWQISGIARAAGAPRSAGAGIDLLCTIGERVAAGEPLYRIHAESAADLATAVAMTGPAGEASTAVRVDPD
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Bifunctional ribose 1,5-bisphosphokinase-thymidine phosphorylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: RECO_BRUME
Sequence: MEWRDEGVILGTRRHGETSAIVEVMTCGHGRHMGMVRGGRSRRMQPLLQPGNHVDVSWWARLDEHMGTFTIEPLSFAAARLIETPVALYGIQLAAAHLRLLPERDPHRGLYETLRLIIEHFDDPLAAGELLLRFEVMMLEELGFGLDLKECAATGRKDDLIYVSPTSGRAVCREAGAPWAEKLLSLPSFVNDTALRASCYDDLDRAFTMTGYFLMRHVWEPRAQTPPDSRSGFLNAVGRAINLSQAS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PIMT_BURO0
Sequence: MSGERAKRFPLALEDLKRAPRKSEGRPGERQAAGAVPKAADKPAAVLKPVAVKPAAVRAPLPGIAAAKPATAPKPTAPKPALPKPAAPSIAPAGAFALTSERVRERMVERLRANGVTDARVLDAMAAVPRHLFVDPGLATQAYEDSALPIGHQQTISKPSVVARMIELAMAGRTLERVLEIGTGCGYQAAVLSHVARDVYSIERIKPLYERAKLNLRPLRVPNIRLHYGDGRVGLPSAAPFDAIVIAAAGLDVPQALLEQLAIGGRLVAPVGAQSGQHQVLTLVERVAHAQWRESRLDRVFFVPLKSGVI
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
Protein: RS10_LACLS
Sequence: MATKKIRIRLKAYEHRILDAAAEKIVETAKRTNAEVSGPIPLPTDRSVYTVIRATHKYKDSREQFEMRTHKRLIDIIEPTQKTVDSLMKLDLPSGVNIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SMG8_CULQU
Sequence: MNPINSFIFPDIPKDLGKILMKDDQQLIVVGIIGKSSTPDCNKLVGFNLLTIHPALTDTDPRDGRVKFYFENDGKILYLHFETTFDQHVMADLLAKAVQTGIQDNFINFNSTVRTRFARVLLFAIQVCHMIVLVEPSSVFDTSYLSIFKSLKIIREKYVLKFLPKLLKSSNLGNYMGKEARLCSPRFIFFFEGTSNIKPEDVEKLDGLECSVEEEIYKMLRNEFIITNNSAMSLFSIPRSKKFVFYNSDKRAKSNPLADSIDLLMKYLNKPAGGQNDDDEDLMSRLRPYDGYGMSAWSVGKSKRAEKKERSILALLKEHVAEAFEHGFDDSASKYRGRGHFVIPSFKTWYEGFKLLHKIFIDNPSNSSYETNDPDYKAFLQNFHKIIDIDERFFAEICEHGLELAMVNYKDMLPHHYSSTFHEKKYEQAHELFTRYARGPEVERHEQKLKDYCDSIWLNGKQQCEYPSLRGNPCALGKHKVKDPTEHSSGVIFVSACNCGRTQGHREDPYTIRQGNYDFYQIIAKSCSSCNVLERVKFPVFEPSSNDFRAAEFINKNLSNLMSFEHSNRTPDASTHPPMTNENSPHLSGSQKSQDSASNLTFSMDEKRDEENKSQKFGTQGEDEDETLEQETVNEIVIKVGEHSEDKAILRQPSTTEYLPGMLHAASPAGLLPQFPSWSLVCLGPSSIYTHNSGIPEHVQSGFLSGANFLLPWDVSVRLEHAQSWAASYEKIRNRKKNTSQPKSSESSNTFTLKIFLGVEYECLRGHRFIMSGPDTVLRGGSGSIVRDSGSKVVFNDMPIYFPCPCRSSNIAQLMRVHVVTPKAPVNVIVEPKVRILQGTTQNCLTFTTGLTEPIKLSQSAYWILRLPFIYEGDSGPLMPPAGVTVANAATHGVLMAGMFGIRESEISEELL
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Probable component of kinase complex containing SMG1 and recruited to stalled ribosomes (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG8, Protein smg-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG8 family.
Protein: UPPP_SYNJB
Sequence: MLLADTWYPNWWQALILGMVQGITEFLPISSTAHLRVFPALVGWPDAGASFTAVIQLGSLGAVLIYFASDLRQLILGSWKAWRERDFQQEPWRLSVGILVGTVPIVVAGWAIKAIWGSPPRQLWVIATAAIGLAVLLGWAEQTGKRQRDLHSLGIWDGIWVGLAQALSLIPGVSRSGSTLTAGLFLHLQRSAAARYSFLLGIPALFLAGVVEFISEFEAEALLPQGLGTLSAFVFSYLSIDWLIQFLQRSSTWLFIVYRIGFGLFIILGLALGFLRP
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TEKT4_HUMAN
Sequence: MAQTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGYQ
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme.  Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity).  Contributes to normal sperm motility (By similarity).
What are the official names of this protein?
Tektin-4.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Note=Found in the abaxial (convex) surface of outer dense fibers in sperm flagella.
Protein: THIE_PHOV8
Sequence: MEDKTVELQFITHFTDTYSYYDSARMALEGGCRWIQLRMKDTPVDEVEREAIRLQGLCKDYGATFVIDDHVELVKKIHADGVHLGKKDMPVAEARGILGKEFIIGGTANTFDDVKMHYKAGADYIGCGPFRFTTTKKDLSPVLGLEGYRSIILQMKEANIHLPIVAIGGITLEDIPSIMETGITGIALSGTILRAKDPVAETKRIMNL
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.