PharMolix/UniProtQA huggingface dataset:
Protein: MARH9_HUMAN
Sequence: MLKSRLRMFLNELKLLVLTGGGRPRAEPQPRGGRGGGCGWAPFAGCSTRDGDGDEEEYYGSEPRARGLAGDKEPRAGPLPPPAPPLPPPGALDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQIAAIVLGSLFLVASISWLIWSSLSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIIHEGSSVYRIFKRWQAVNQQWKVLNYDKTKDIGGDAGGGTAGKSGPRNSRTGPTSGATSRPPAAQRMRTLLPQRCGYTILHLLGQLRPPDARSSSHSGREVVMRVTTV
What is the function of this protein?
E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF9, Membrane-associated RING finger protein 9, Membrane-associated RING-CH protein IX, MARCH-IX, RING finger protein 179, RING-type E3 ubiquitin transferase MARCHF9.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein.
Protein: RL14_STAAW
Sequence: MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GSA_VIBC3
Sequence: MTKSAELYQKAQTTIPGGVNSPVRAFNGVGGSPIFIDRADGALIFDADGKAYIDYVGSWGPMILGHNHAVIREAVIQAAQRGLSFGAPTEMEITMAELVSELVPSMEQLRMVNSGTEATMSAIRLARGYTGRDKIIKFEGCYHGHADSLLVKAGSGALTLGQPSSPGVPADFAKHTLTARFNDLDSVRELFAANQGEIACIIVEPVAGNMNCIPPVEGFHEGLREICDQEGALLIFDEVMTGFRVALGGAQAHYNIKPDLTTLGKVIGGGMPVGAFGGRREVMQYIAPTGPVYQAGTLSGNPIAMAAGYACLNLLREEGNEKRLAAKTKQLADGFKSLADQHGIPLLVHQVGGMFGFFFTEQETVTCYEDVARCDVERFKRFFHLMLQHGVYLAPSAFEASFTSLAHGSKEIEATLEAADRSFAILAAEAKA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_PSEPF
Sequence: MPGTLGFRELGQMAYEPVWQAMQRFTNERGTTAPDEIWLVEHPPVFTQGQAGKAEHLLLPGDIPVVQVDRGGQVTYHGPGQLVAYLLLDVRRLGFGVRDLVSRMERCLIELLASYGVTAVAKPDAPGVYIDGAKIASLGLRIRHGCSFHGLALNVDMNLEPFRRINPCGYAGLAMTQLSEHAGSIEFAEVSARLRAQLVKHLDYAEQTTLTGGID
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_CLOBA
Sequence: MKVILLQDVKKIGKKGEVIEASDGYARNFLFPRKLAQEATDSNMHILNNKKENERKKKLAEIEAAQKLAGELKGKEITIKTKIGESGKLFGAITSKDIASLIKTQYNVEIDKKKIVMDTIKLAGNYDIEVKLYPEVSTKMKVNILPQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NADK_CLOK1
Sequence: MKNIGINVNTTKDPNKEMLNFIIESIKNIDKSVNIKTYENCMGLDENESSSLDVIIVLGGDGTILNTSRNVLRSKTPILGINIGHLGFLAQVEINSVEAALEKLFRGEYTIEKRDMIQCTYNEGNKIKRYDGLNDVVLYRGIKSRIQRYDVYINDAFYNSFSGDGIIICTSTGSTAYNLSAGGPIIHPLLDVLCLTPMYSQFFASRSIVLDSRSLISISIEKNYEDSFLSIDGQKWVAVNGSQTIKINKSKNKRRLIKFDDAYFNTLREKIIFNAKGCEGGIL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AF151_ALTAL
Sequence: MKVTITSIDQVLPSVEITAPKSLALSHIDEWHSRGRSSLVWLYPKPKKPTQSLQLLDHLRSSLSQALNKFPQYAGKLSHSLQTGTSQKSKTRLCLTWGTGNDPGVHYITARASSPIDALLPPLGTSTGFTNGSGSYAWDRSGRSCIGLWPAVPLNKVYETCIQITTFECGGFSLSITMNHAVADATSVILFARHWSKTHELMVKVQTPSLSIAEPCFAPHLIDQYSTLELQDEGDNGKLLNKAHALPTLRNDLYESGARSLPDRLELSETYSVGDDIAVGDWERSGPMRSYMLHFSKEDINKIWESAKKEAGQDVSRQAAIVSYIWLAIIRAREWDKHGVCEPIKLFITFDVRRRLGLPDTLLGSPVLVTHVKFNGNDAISKSHGLLANRIWKTLSTYDVESVCAALYDITSSRPLISPAIWLGGRSTLFSSLCHADMYDVTFHETGPLLAAPAFAGMGGMIGLIKSKSAVPSRLPETYEDGIDMFFELDTESSIKLFSDPALSIFDGRALLQEFRQ
What is the function of this protein?
Acyltransferase; part of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AF-toxins responsible for Alternaria black spot of strawberry disease by the strawberry pathotype (Probable).  AF-toxin I and III are valine derivatives of 2,3-dyhydroxy-isovaleric acid and 2-hydroxy-isovaleric acid respectively, while AF II is an isoleucine derivative of 2-hydroxy-valeric acid (PubMed:15066029, Ref. 4, PubMed:22846083).  These derivatives are bound to a 9,10-epoxy-8-hydroxy-9-methyl-decatrienoic acid (EDA) moiety (PubMed:15066029, Ref. 4, PubMed:22846083).  On cellular level, AF-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).  The aldo-keto reductase AFTS1 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV) by reduction of its ketone to an alcohol (PubMed:15066029).  The acyl-CoA ligase AFT1, the hydrolase AFT2 and the enoyl-CoA hydratases AFT3 and AFT6, but also the polyketide synthase AFT9, the acyl-CoA dehydrogenase AFT10, the cytochrome P450 monooxygenase AFT11 and the oxidoreductase AFT12 are all involved in the biosynthesis of the AK-, AF- and ACT-toxin common EDA structural moiety (PubMed:12019223, Ref. 4, PubMed:18986255).  The exact function of each enzyme, and of additional enzymes identified within the AF-toxin clusters have still to be determined (PubMed:12019223, Ref. 4, PubMed:18986255).
What are the official names of this protein?
Acyltransferase AFT15-1, AF-toxin biosynthesis protein 15-1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: CH601_BRASO
Sequence: MAAKDVKFSTDARDRMLRGVDILANAVKVTLGPKGRNVVIEKSFGAPRITKDGVTVAKEIELEDKFENMGAQMVREVASKTADLAGDGTTTATVLAQAIVKEGAKSVAAGMNPMDLKRGIDLAVEAIVKDLKAHAKKITSNDEIAQVGTISANGDSEIGRFLAEAMQKVGNEGVITVEEAKSLDTELEVVEGMQFDRGYVSPYFVTNSEKMRVELEDPYILIHEKKLSGLQTMLPLLEAVVQSGKPLLIVAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGTTISEDLGIKLENVTLSMLGRAKKVVIDKENTTIVDGAGAKKDIEARTQQIRLQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKERKDRVDDALHATRAAVEEGILPGGGVALLRATKVLDGVKTANADQKAGVDIIRRAIQVPVRQIVQNAGDDGSLVVGKLLEKDSYSWGFNAATGEYQDLVQAGVIDPAKVVRTALQDAASVASLLITTEALVADKPKKAETAAAPAMDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCNT3_BHV4V
Sequence: MKMAGWKKKLCPGHHLWALGCYMLLAVVSLRLSLRFKCDVDSLDLESRDFQSQHCRDMLYNSLKLPAKRSINCSGITRGDQEAVVQALLDNLEVKKKRPPLTDTYYLNITRDCERFKAQRKFIQFPLSKEELDFPIAYSMVVHEKIENFERLLRAVYAPQNIYCVHVDVKSPETFKEAVKAIISCFPNVFMASKLVPVVYASWSRVQADLNCMEDLLQSSVSWKYLLNTCGTDFPIKTNAEMVLALKMLKGKNSMESEVPSESKKNRWKYRYEVTDTLYPTSKIKDPPPDNLPMFTGNAYFVASRAFVQHVLDNPKSQILVEWVKDTYSPDEHLWATLQRAPWMPGSVPSHPKYHISDMTAIARLVKWQYHEGDVSMGAPYAPCSGIHRRAICIYGAGDLYWILQNHHLLANKFDPRVDDNVLQCLEEYLRHKAIYGTEL
What is the function of this protein?
Non-essential glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides.  Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis.  Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans.  Contributes to the post-translational modifications of structural proteins.
What are the official names of this protein?
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, BORFF3-4, C2GnT-mucin type, C2GnT-M.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: MED7_MOUSE
Sequence: MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHSEAGMRVKAEPMDTDDNSNCPGQNEQQRESSGHRRDQIIEKDAALCVLIDEMNERP
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Cofactor required for Sp1 transcriptional activation subunit 9, CRSP complex subunit 9, Mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OTC_PACTA
Sequence: MINSISNTVLLKSVVSKRFFSSSAKMSSQAKPRHLVSMLELSIKELESLVNRAAYHKQQIRSGLVNTTQPLSGKTVSLIFNKRSTRTRVSSEGAAAYLGGCPMFLGKDDIQLGVNESLHDTTKIISSMTSSIFARVNKHSDIQEMCKYSSVPIINALCDTFHPLQAITDILTIKESFGNTTKGLKLAWIGDVNNVINDLCIAALKSGIDVSIAVPSGLKFEELILSGAKEISAENGTTLKITNDPLEAINGANVIVTDTWISMGQEDERLQKLKQFEGFQITKEMISKGKAAENWKFMHCLPRHPEEVHDEVFYDEERSLVFEEGENRLYAAIAVLEGFVVNKGKLL
What are the official names of this protein?
Ornithine transcarbamylase, mitochondrial, OTCase, Ornithine carbamoyltransferase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: YT68_CAEEL
Sequence: MSKDCKMVSELCEKVSKIMTVVKELRAEHRREFVQKPEEIEMDVFWRQTFVRFTEPAEKWSNIRHRPAPATTPIDIVYPLREQDW
What are the official names of this protein?
Uncharacterized protein B0563.8.
Protein: MPI_SCHPO
Sequence: MYRLKCDVKSYGWGKVGHESLAAKLAEAGYGFEVDPNTPYAELWMGSHPSGPSFVMQTGKPLSELLTPETVGEKVYKKYGKQLPFLFKVLSINKVLSIQAHPDKPLGKQLHKTNPKEYKDDNHKPEMAVALTEFDALCGFRPVKQIEQFLDSIAPLREFVGEEAVRQFKGTVKQDERKALETLFNELMHKDEKRIQEFTPQLVQLAKSDANNFGGTEYGGKAFSDLIIHLNSQFPDDIGLFVTPFLNYVRLHPGEAVFLRALDPHAYVSGNIIECMAASDNVIRLGFTPKFKDIETLVNNLTYQTADAKSQLTQPVPFAKACGSGKTLLYDPPIEEFSILQTKVSPGQKQCIRGINGPSILLVTEGSGILNGDKGDVASISPGFVYFISANFPLTISATSEPVVVYQAFCEI
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
What are the official names of this protein?
Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS21_PROMT
Sequence: MTQVTVGENEGIESALRRFKRQVSKAGIFGELKRLRHHETPVEKYKRKLQQRRRSRRR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: Y1128_HAEIN
Sequence: MVYHNSMCTYLFYNKIGFGLDYQLSVYLGLATTIVCIVLFFTMLKPLGTRDEEAYINN
What are the official names of this protein?
Uncharacterized protein HI_1128.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GCH1_STRGG
Sequence: MTDPVTLDGQGSIGAFDEKRAEAAVRELLIAVGEDPDREGLRETPGRVARAYKEIFAGLYQEPEDVLTTTFDLGHDEMVLVKDIEVFSTCEHHLVPFRGVAHVGYIPATTGKITGLSKLARLVDVYARRPQVQERLTTQIAESLMSILEPRGVIVVVECEHMCMSMRGIRKPGAKTLTSAVRGQLRDPATRAEAMSLIMAR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: DPP6_RAT
Sequence: MASLYQRFTGKINTSRSFPAPPEASHLLGGQGPEEDAGSKPLGPQAQAVAPRERGGAGGRPRFQYQARSDCDEEDELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAEDTSLSQKKKVTVEDLFSEDFKIHDPEAKWISDKEFIYRERKGSVILRNVETNNSTVLIEGKKIESLRAIRYEISPDKEYALFSYNVEPVYQHSHTGYYVLSKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKSHIAHWWSPDGTRLAYATINDSRVPLMELPTYTGSVYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFVRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTEILTYDEKRNKLYFLSTEDLPRRRHLYSANTVDDFNRQCLSCDLVENCTYVSASFSHNMDFFLLKCEGPGVPTVTVHNTTDKRRMFDLEANEQVQKAIYDRQMPKIEYRKIEVEDYSLPMQILKPATFTDTAHYPLLLVVDGTPGSQSVSERFEVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGFLEEKDQMEAVRTMLKEQYIDKTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKLAHRVSALEDQQFLIIHATADEKIHFQHTAELITQLIKGKANYSLQIYPDESHYFHSVALKQHLYRSIIGFFVECFRIQDKLPTATAKEDEEED
What is the function of this protein?
Promotes cell surface expression of the potassium channel KCND2 (PubMed:12575952).  Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:12575952, PubMed:16123112, PubMed:19279261, PubMed:19901547).  Has no dipeptidyl aminopeptidase activity (By similarity).
What are the official names of this protein?
Dipeptidyl aminopeptidase-like protein 6, DPPX, Dipeptidyl aminopeptidase-related protein, Dipeptidyl peptidase 6, Dipeptidyl peptidase IV-like protein, Dipeptidyl peptidase VI, DPP VI.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: PHLC_STAA8
Sequence: MVKKTKSNSLKKVATLALANLLLVGALTDNSAKAESKKDDTDLKLVSHNVYMLSTVLYPNWGQYKRADLIGQSSYIKNNDVVIFNEAFDNGASDKLLSNVKKEYPYQTPVLGRSQSGWDKTEGSYSSTVAEDGGVAIVSKYPIKEKIQHVFKSGCGFDNDSNKGFVYTKIEKNGKNVHVIGTHTQSEDSRCGAGHDRKIRAEQMKEISDFVKKKNIPKDETVYIGGDLNVNKGTPEFKDMLKNLNVNDVLYAGHNSTWDPQSNSIAKYNYPNGKPEHLDYIFTDKDHKQPKQLVNEVVTEKPKPWDVYAFPYYYVYNDFSDHYPIKAYSK
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture.  Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins.  Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine.
What are the official names of this protein?
Phospholipase C, Beta-hemolysin, Beta-toxin, Sphingomyelinase, SMase.
What is the protein family that this protein belongs to?
Belongs to the neutral sphingomyelinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: HRCA_BACCZ
Sequence: MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDAITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLAPQNLPKDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANMLSQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSRVISLLQLFTRQFTDGLKK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: YUAT_ECOLI
Sequence: MFEDPEIRIHKLQPCTQCPRLEDLWFSWYFRYIHDRCLRSSACHQDIHGASLYAPLALKQTYEVYFGYDCTLRKYGRFRQKLPVKTDFRKNGARRRPVTGRSPRTGEEAQWICNHSEQVRPEAFIIGSVCCFSGMIYPHIQRPDPVNRSMNDQ
What are the official names of this protein?
Uncharacterized protein YuaT.
Protein: RR2_PHATC
Sequence: MSDISLSQLLEAGVHFGHKAYRWNPKMFPYIYSEVNNIHILDLVQSATLLKEANLYLESAARENKTFLFVGTKRQASTLIAQEAKRCDSYYVNHRWLGGMLTNWSTLKERIAHLKDLEQQEANNTFDLLTKKEGALRRKELKKLRRHLDGIKDMKNLPDIAIVIDQKRETTAIRECRKLGIPVVSILDTNCDPDLVDIPIPGNDDAVRSIKLILKSLTDSILIGKS
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RIMM_BURP1
Sequence: MAGHDSGNAKRGRSPSFGVFVRKPVERASAKGTSDGAVDSQAIRIDAAQSWPDDAVEVGAVVDAYGLKGWVKLAAHAGAGRGGDALLKARDWWLQKGAERKFARVTQAKLHGDTVVAHPDGSVDRDTALALRGARVFVRRGDFPALAADEFYWVDLIGLDVVNEAGVALGKIADMIDNGVHSIMRVEYPATGKDGRPKTGERLIPFVGVYVKAVEQAAGRVVVDWEADY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST17B_HUMAN
Sequence: MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSLPNPHELVSDLLC
What is the function of this protein?
Phosphorylates myosin light chains (By similarity).  Acts as a positive regulator of apoptosis.
What are the official names of this protein?
Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment. Note=Colocalizes with STK17B at the plasma membrane.
Protein: SYS_ALKOO
Sequence: MLDIKRIRNNLDEIKAAMARRGEKDFDLDAVVALDEKRRELLQQVELMKNEQNTVSKEVPKLKKEGKDATEVMARMKELSGKIKELDGQVKEVEDQLEYTLLRIPNVPHPDVPQGETDDDNIEVRKWSEPTHFDFEPKAHWDIATDLGIIDFEAASKITGARFALYKGVGARLERALINFMLDLHIEEHGYTEVLPPFMVNRSSMTGTGQLPKFEEDAFKLPQKDYFLVPTAEVPVTNMHRDEIIEGANLPLSYVAYTPCFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYAELEKLTNNAEKVLQLLEIPYRIVRICTGDLGFTAAFKYDIEVWMPSYNRYVEISSCSNFEDFQARRANIRYRPEEKGKVEFLHTLNGSGLAVGRTVAAILENCQDDEGNVKIPEALIPYMRGIKVITK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_ACTP7
Sequence: MSYTVIYAGTFDPMTNGHLDIIERASELFGQVIVAVAKNPSKQPLFSLEERTALVRQSCAHLANVQAVGFSGLLADFAKQHQAKALVRGIRGSDDIEYEIRLAQLNDKLSGRLDTVFLPPSVTWRYLSSTMVREIYRHQGDVAQFVPNAVLCALKEKE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_PARDP
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKYFGEFKAYDQIDGAPEERARGITISTAHVEYESENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVNAADGPMPQTREHILLGRQVGIPYMVVYLNKVDQVDDPELLELVEMEVRELLSSYDYPGDDIPIVKGSALAALEGRDAEIGENSIRELMKAVDDYIPTPERAVDLPFLMPIEDVFSISGRGTVVTGRVERGAVNVGDELEIVGIRPTKKTTCTGVEMFRKLLDRGEAGDNIGALLRGVERDGVERGQVLAKPGSVTPHTEFEAEAYILTKEEGGRHTPFFANYRPQFYFRTTDVTGTVKLPEGTEMVMPGDNLKFEVELIAPIAMEEKLRFAIREGGRTVGAGVVSKILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_ESCF3
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVLMPVVQPSELWQESGRWEQYGPELLRIADRGDRPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.