PharMolix/UniProtQA huggingface dataset:
Protein: BIOD_NEOSM
Sequence: MAIFITGTDTNVGKTIISTWICLHLGWGYFKPIQTGGNSDSDFVSSTTGVPAYDSVFSFPDPIAPHVAAKMSGSSIDILKIQLPEYRKSLSNKINSIPTTEHGRSKFISATTQTKYWEKENNKIVIEGAGGVLVPLQENGTKMVDLIQHLNVPVIIVSRSTLGAINHTLLTLEALQAREIKVLGIVINSMCEDFLDYNSKAIAEYGSTEILATFPYLKEVTRDSILSVQMGDSMKALLESTLKCKNSLL
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_DEHMB
Sequence: MFFGEFEYKLDEKGRFPLPPAIRPSLKDGLILAPGTGEKCIYAYPLCEWKKLAESLKSTTVAPSKMRRLNRALFALAFDVNLDAQGRLTLPAPLKTYAGVNIEVIVAGVNNYLEIWDKETWESEKKASQEQAWQIIETLEEH
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y260_SHESR
Sequence: MTLGQQAESLAQGYLEQQGLTFVERNVRYPFGEIDLVMRHKKHWVFVEVKYRSANQFGGAIQALSKAQIGRIRMAASHYLQTHKLDVPCRFDVVAIEDAQIHWLVDAF
What are the official names of this protein?
UPF0102 protein Shewmr7_0260.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: ZP4_RAT
Sequence: MARQALRSTLWLLPSILLCFPFCLPLSGQHVTELPGVLHCGLQSFQFAVNLSLEAESPVLTTWDSQGLPHRLKNDSDCGTWVMDSPDGFLVLEASYSGCYVTLEGSHYIMTVGVQEADVAGHVAGTRQRLLTCPLALQGKAPDTPNAKVCSPVPVKERLPCASSTISRGDCEELGCCYSSEEEGADSCYYGNTVTSHCTKEGHFSIAVSRDVTSPPLRLDSLRLGFRNITTGCDPVMKTSTFVLFQFPLTSCGTTQRITGDQAMYENELVAIRDVQAWGRSSITRDSNFRLRVSCTYSIHSIMSPVNMQVWTLPPPLPKTQPGPLSLELQIAQDKNYSSYYGTDAYPLVKFLQDPIYVEVSILHRTDPSLSLLLEQCWATPGSNPFHQPQWPILVKGCPYAGDNYQTKRIPVQKASDVFPSHHQRFSISTFSFMSAGREKQVLGGQVYLHCSASVCQPAGMPSCTVICPASRRRRKSELYFDNSTSISSKGPVILLQATKDPAVMLHKHSGTHADSPTLWVMGLSASMVITGVLVVSYLATRKQR
What is the function of this protein?
Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy.  The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4.  ZP4 may act as a sperm receptor.
What are the official names of this protein?
Zona pellucida sperm-binding protein 4, Zona pellucida glycoprotein 4, Zp-4, Zona pellucida protein B.
What is the protein family that this protein belongs to?
Belongs to the ZP domain family. ZPB subfamily.
What are the subcellular locations of this protein?
[Processed zona pellucida sperm-binding protein 4]: Zona pellucida. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: VP2_ROTYO
Sequence: MAYRKRGVKRENLPQQHERLQEKEIENNTDVTMENKNNNRKQQLSDKVLSQKEEIITDVQDDIKIADEVKKSSKEESKQLLEILKTKEDHQKEVQYEILQKTIPTFEPKESILKKLEDIRPEQAKKQMKLFRIFEPRQLPIYRTNGEKELRNRWYWKLKKDTLPDGDYDVREYFLNLYDQILIEMPDYLLLKDMAVENKNSRDAGKVVDSETANICDAIFQDEETEGVIRRFIADMRQQVQADRNIVNYPSILHPIDHAFNEYFLNHQLVEPLNNEIIFNYIPERIRNDVNYILNMDMNLPSTARYIRPNLLQDRLNLHDNFESLWDTITTSNYILARSVVPDLKEKELVSTEAQIQKMSQDLQLEALTIQSETQFLAGINSQAANDCFKTLIAAMLSQRTMSLDFVTTNYMSLISGMWLLTVIPNDMFLRESLVACELAIINTIVYPAFGMQRMHYRNGDPQTPFQIAEQQIQNFQVANWLHFINNNRFRQVVIDGVLNQTLNDNIRNGQVINQLMEALMQLSRQQFPTMPVDYKRSIQRGILLLSNRLGQLVDLTRLVSYNYETLMACITMNMQHVQTLTTEKLQLTSVTSLCMLIGNTTVIPSPQTLFHYYNVNVNFHSNYNERINDAVAIITAANRLNLYQKKMKSIVEDFLKRLQIFDVPRVPDDQMYRLRDRLRLLPVERRRLDIFNLILMNMEQIERASDKIAQGVIIAYRDMQLERDEMYGFVNIARNLDGYQQINLEELMRTGDYGQITNMLLNNQPVALVGALPFVTDSSVISLIAKLDATVFAQIVKLRKVDTLKPILYKINSDSNDFYLVANYDWIPTSTTKVYKQVPQPFDFRASMHMLTSNLTFTVYSDLLSFVSADTVEPINAIAFDNMRIMNEL
What is the function of this protein?
Inner capsid protein that self-assembles to form an icosahedral capsid with a T=2 symmetry, which consists of 120 copies of VP2, with channels at each of its five-fold vertices.  This capsid constitutes the innermost concentric layer of the viral mature particle.  It encapsidates the polymerase VP1, the capping enzyme VP3 and the genomic dsRNA, thereby defining the core.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels formed by VP2 N-termini.  VP2 is required for the replicase activity of VP1 polymerase.  Probably recruits a copy of a VP1-VP3 complex, potentially along with a segment of plus-strand RNA, as a decamer of VP2 assembles.  May activate the autoinhibited VP1/RNA complex to coordinate packaging and genome replication.
What are the official names of this protein?
Inner capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP2 family.
What are the subcellular locations of this protein?
Virion. Note=Inner capsid protein. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RL2_SORC5
Sequence: MGIRSFKPTSPARRYYSVSDFKEITKVEPERSLLEQQTSTGGRNNNGRITSRFRGGGHKQRYRIIDFRRDKIGVPAKVATIEYDPNRTARIALLHYVDGEKRYILAPDGLAVGATLLASRNADIKPGNSLTLRFIPPGTSIHNVEVKKGKGGQLVRSAGVAAQLMAKDGDYAQVRLPSGEIRKVHLDCRATIGQVSNSEHANISLGKAGRSRWLGRRPHNRGVTMNPVDHPMGGGEGRTSGGRHPCSPWGQLSKGLKTRNNKRTDGMIVRRRGTKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ERPA_ACIAD
Sequence: MNAQALVITDNAAKKVRQLRDSEGNQDLMLRVYVTGGGCSGFSYGFNFADSPNEDDAEFVNGDVKMLVDSLSYQYLVGSVVDYIEGLEGSRFIIQNPNATTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RL24_THEKO
Sequence: MKLDMKQPRKQRKFLYNAPLHLRGKIMSAPLSKELREKYGVRNLPIRVGDKVKVMRGDFKGVEGKVVEVDLRRYRIHVEGVTHKKTDGTEVFYPLHPSNVMIVELNLEDEKREKIIERRAA
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: EFP_SALSV
Sequence: MATYYSNDFRSGLKIMLDGEPYAVESSEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_LEPBP
Sequence: MFQWIYESFGNDYGFLRVFSYVTLRAMMAGLTSMFITFIFGKSLISFLLSLKFRESVRNDGPQSHANKSGTPTMGGLIMILSLTISTLLWGNLSNWNVILLLISAILFAGLGFTDDYMKSVKKIKGGMRARTKFIVTILFAVTITTLYFYYTGKSNVNLQKGIVFSITDLFLPFVKGPVWNLGIFAVPFAIIVLIGSSHAVNLTDGLDGLASGTVVISTATFALIAYVSGTPSAANYLHIPYLPGSHEYSVFLAGLSGALLGFLWFNCHPAQVFMGDTGSLFLGSTLGLVAIMLKKEILLVILGGIFVAEAVSVILQVGSFKLTGKRIFKMAPLHHHFELSGWSEEKVVIRFWIIGIILAIITLSTLKIQ
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURG_STRPI
Sequence: MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQEILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGGFVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGAVTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNIINLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIVPLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKASKELKSLADFYQLLKKDLS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CCME_BRUME
Sequence: MSATAEQNARNPKGKGGFARTVSQRKRKRLFLIGGALAVLAVAVGLMLTAFNQDIRFFRTPADLTEQDMTSGARFRLGGLVEEGSVSRTGSELRFTVTDTIKTVKVVFEGIPPDLFREGQGVVAEGRFGSDGLFRADNVLAKHDENYVPKDLADSLKKKGVWEGK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: TRPA_FRATW
Sequence: MTNRYTTLFANLEKRNEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGIPFSDPLADGPTIQEANIRALESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADVPAHESKEFRDIAKKVSIAQIFIAPPDASESTLKQISELGSGYTYLLSRVGVTGTETAANMPVEDVLTKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVKIIQNNISNKQKMLNELTYFVKEMKAATLN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: KAD_LISMH
Sequence: MKLVLMGLPGAGKGTQAEQIVEKYNIPHISTGDMFRAAMKNNTELGRKAKSFMDNGDLVPDEVTNGIVRERLSEDDAKDGFLLDGFPRTVEQAQELENILSDLGTELDAVINIDVEKDVLMKRLTGRWICRTCGKTYHEIYNPPKVAGKCDLDGGELYQRDDDKKETVEKRLNVNMKQTKPLLDFYSEKGKLHNINGEQDIKDVFVDVEKILTSF
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FACR2_BOVIN
Sequence: MSMIAAFYGGKSILITGATGFMGKVLMEKLFRTSPDLKVVYILVRPKQGQTLQQRVFQILDSKLFEKVKEVCPNVHEKIRAISADLNQNDFAISKEDMKELLSHTNIIFHCAATVRFDDHLRHAVQLNVTATQQLLLMASQMPKLEAFIHISTAFSNCNLKHIDEVVYPCPVEPKKIIDSMEWLDDAIIDEITPKLIGDWPNTYTYTKALGEVVVQQEGGNLNIAIIRPSIMGATWQEPFPGWVDNLNGPSGLIIAAGKGFLRSIRATPMAVADLIPADTVVNLTLAVGWYTAVHRPKSTLVYHCTSGNLNPCNWGKMGLQVLATFEKIPFERAFRRPNADFTTNNITTHYWNAVSHRAPAIIYDFYLRLTGRKPRMTKLMNRLLRTLSMLEYFVNRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKKYLLKEDMAGIPEAKQHLKRLRNIHYLFNTALFLIAWRLLIARSQVARNVWFFIVSFCYKFLSYFRASSTLNV
What is the function of this protein?
Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols.  A lower activity can be observed with shorter fatty acyl-CoA substrates.  It may play a role in the production of ether lipids/plasmalogens and wax monoesters which synthesis requires fatty alcohols as substrates.
What are the official names of this protein?
Fatty acyl-CoA reductase 2.
What is the protein family that this protein belongs to?
Belongs to the fatty acyl-CoA reductase family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: PPE04_MYCTU
Sequence: MAAPIWMASPPEVHSALLSNGPGPGSLVAAATAWSQLSAEYASTAAELSGLLGAVPGWAWQGPSAEWYVAAHLPYVAWLTQASADAAGAAAQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVATNFFGINTIPITLNEADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGGAASTVGAVNPWQWLLALLQQLWNAYTGFYGWMLQLIWQFLQDPIGNSIKIIIAFLTNPIQALITYGPLLFALGYQIFFNLVGWPTWGMILSSPFLLPAGLGLGLAAIAFLPIVLAPAVIPPASTPLAAAAVAAGSVWPAVSMAVTGAGTAGAATPAAGAAPSAGAAPAPAAPATASFAYAVGGSGDWGPSLGPTVGGRGGIKAPAATVPAAAAAAATRGQSRARRRRRSELRDYGDEFLDMDSDSGFGPSTGDHGAQASERGAGTLGFAGTATKERRVRAVGLTALAGDEFGNGPRMPMVPGTWEQGSNEPEAPDGSGRGGGDGLPHDSK
What is the function of this protein?
Important for the siderophore-mediated iron-acquisition function of ESX-3.
What are the official names of this protein?
PPE family protein PPE4.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEPA_RICAE
Sequence: MNHQKYIRNFSIIAHIDHGKSTLADRLIEHCGGLQAREMSQQVLDSMDIEKERGITIKAQTVRLVYKAKDGNTYYLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDSTQGVAAQTLANVYQAIENDHEIVLVLNKLDLPASEPEQVKQQIEDIIGIDTSDAVLISAKSGIGIDLVLEAIVNKLPPPKESSSDILKALLVDSWYDQYLGVVILVRVIDGYLRKNMRIKMMATNSVYTVENVGYFTPKKHISDVLHAGEIGFFTAAIKQVADCKVGDTITDEKKPCEQALPGFKPNLPVVFCGLYPTDSSEFEHLKDSLAKLRLNDASFEYEMESSSALGVGFRCGFLGLLHLEIIQERLSREFDLDLITTAPSVVYKIHMQDGENLEIHNPADLPNLQKIESMEEPWIKATIMVPDEFLGAVLSLCTEKRGMQLDHSYIANRAKIIYKLPLNEIVYDFYDRLKSCSKGYASFEWQMDVYEPSELVKLGILVNAEVVDALSTIVHRSRAEQRGRALCVRLKDLIPRQQIDIAIQASIGSRIIARETIKALRKDVLSKCYGGDISRKRKLLEKQKAGKKRMRQYGNIEIPQSAFIAALKIGDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VP7_ROTMB
Sequence: MYGIEYTTALTFLISFLLLRYILKLVVKIMDFIVYRFLFVILILSPCIKAQNYGINLPITGSMDMAYANSTQSETFLTSTLCLYYPKEAATEINDNSWKDTLSQLFMTKGWPTGSVYFKEYNDIAVFSIDPQLYCDYNVVLMKYDASLQMDMSELADLILNEWLCNPMDITLYYYQQTDETNKWISMGSSCTIKVCPLNTQTLGIGCLTTDATTFEEIATAEKLAITDVVDGVNHKLNVTTTTCTIRNCKKLGPRENVAVIQIGGSDVIDITADPTTAPQTERMMRINWKKWWQVFYTVVDYVNQIISAMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: Y2872_HALH5
Sequence: MVHMRDVWVNWFEGEENGYNVCDFFEWRSDDRIEVLDQVVVVRVSPPLFDYIENQMSDLPEDLLQDVYQKSYLRKNMSRIQLDYAFVASDGERIIAVDTMGYKTPIRKSRLTPRQEQLVYELLQNESDICYDLQGHEPKKEHHILSPDPMEMKGLTRKERQLKQLLYMALDQLFTSGNEAEIRYWLTEWEPDRYDEIQGMDHHQAWETLYRDVRQGWSEHHYHFCESLIKGQAFFEKLWELEHGESVK
What are the official names of this protein?
UPF0736 protein BH2872.
What is the protein family that this protein belongs to?
Belongs to the UPF0736 family.
Protein: CENPC_HUMAN
Sequence: MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVPNSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKILATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQKRETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPSGSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIEDEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLANDKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQKQRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPPVGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPVYSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGSGGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSGYTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIPKNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSKRKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDLVRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLLCTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR
What is the function of this protein?
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.  CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
What are the official names of this protein?
Centromere protein C, CENP-C, Centromere autoantigen C, Centromere protein C 1, CENP-C 1, Interphase centromere complex protein 7.
What is the protein family that this protein belongs to?
Belongs to the CENP-C/MIF2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Chromosome, centromere. Note=Localizes exclusively in the kinetochore domain of centromeres.
Protein: Y1111_ACIC1
Sequence: MTGDVRRLPDGHAAPALNPLTGIKLVVLTGLSGAGRSTAAKCLEDLGWFVVDNLPPGLLDTMVDLGVRSGGAINKIAAVVDVRSRAFTSDLYGALGVLRNRGTALRIVFLEASDDELIRRFENVRRPHPLQGDGRLADGIARERELLRDVRGVADLVIDTTNLNVHELRGKIIAAFSDDNQPALRATVVSFGYKYGLPADADLVVDCRFLPNPHWVDELRPLTGRDDAVREYVLAQPGAQDFLDTYSKVLGTVVDGYLREGKRYLTLAVGCTGGKHRSVVIAEELAERLRRLATAESRIDVQVAHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Acel_1111.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: SELB_MOOTH
Sequence: MDYIVVGTAGHVDHGKTVLVKALTGVDTDRLKEEKERGISIELGFAPLTLPSGRQLGLVDVPGHERFIRQMLAGVGGMDLVMLVVAADEGVMPQTREHLAIIDLLQIKKGIIVITKIDLVEADWLELVREEVRQAVKGTVLEDAPLVEVSALTGEGIAELREQLDALAAVTPPRPAAGRVRLPIDRVFSVTGFGTVVTGTLWSGTIKVGDELEVQPEGLKTRARNLQVHGRTVKEARAGQRVAVNLAGIETEAVHRGSSLLTPGFLTPTYRLDASFKLLNGARPLANRDRVHFYLGTSEALGRVVLLDRDELNGGEEALIQLLMEKPVVASREDRFILRSYSPMETIGGGIIIDPVPPKHRRFQPEVLVSLQRRLEGSPEKILAQIIQEHREGLDWQEAATRASLSLEETRKLLQSMAAAGQVTLLRVENDLYAISTERYQAWWQAVTRALEEFHSRYPLRPGLAREELRSRYFSRLPARVYQALLEEWSREGRLQLAANTVALAGFTPSFSETQKKLLKDLEDKYRVSRWQPPSFKEVAGSFNLDPSELEELLHYLVREGVLVKINDEFYWHRQALGEAREVIKNLASTGPFGLAEARDALGSSRKYVLPLLEYLDQVKFTRRVGDKRVVVGN
What is the function of this protein?
Translation factor necessary for the incorporation of selenocysteine into proteins.  It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon.  SelB binds GTP and GDP.
What are the official names of this protein?
Selenocysteine-specific elongation factor, SelB translation factor.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. SelB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM2_PETHY
Sequence: MACGDYDDKLSLDLIRDSLIRQEDTIIFNLIERIKFPINSTLYKKPSSWFPDFTGSLFQYLFQETEALQSKVGRYLSPEENPFFPDNLPASIVPPSKCPPVLHPVAESININEKILDVYLNQLLPLFCTEADEGNYATTAACDIQLLQAISRRIHYGKFVAEVKFRDCSDEYTPLILAQQDRDALMKLLTFEVVEEMVKKRVAKKAMIFGQEVTLVDNAKEVKCKVDPLLVSRLYDEWIMPLTKHVQVEYLLRRLDQNKLTSI
What is the function of this protein?
Mediates the conversion of chorismate to prephenate.
What are the official names of this protein?
Chorismate mutase 2, PhCM2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RBFA_CROS5
Sequence: MANSRRVSRVSSLIKREVSQMLLFDIKDDRVGAGMVSVTDVDLSGDLQHAKIFVSIYGTEEAKVETMEGLKSSEGYVRKELAQRIRLRRAPEVRFFEDHGIERGDKMLHLLNEIRETIPPEDESYNTED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPC_SALCH
Sequence: MIGLRPAFSTMLFLLLLTGGVYPLLTTALGQWWFPWQANGSLIHKDNVIRGSALIGQSFTAAGYFHGRPSATADTPYNPLASGGSNLAASNPELDAQIQARVAALRAANPQASSAVPVELTTASASGLDNNLTPGAAAWQIPRVAAARQLPVEQVAQLVAEYTHRPLARFLGQPVVNIVELNLALDALQGHRAK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.