PharMolix/UniProtQA huggingface dataset:
Protein: URE1_RHOPS
Sequence: MSVKISRSVYADMFGPTTGDRVRLADTDLIIEVEKDFTTYGEEVKFGGGKVIRDGMGQSQVTNKDGAADTVITNALIVDHWGIVKADVAIKAGMISAIGKAGNPDIQPGVDIIIGPGTDVIAGEGKILTAGGFDSHIHFICPQQIEHALMSGVTTMLGGGTGPSHGTFATTCTPGPWHIGRMIQSFDAFPVNLGISGKGNAALPGALIEMVEGGACALKLHEDWGTTPAAIDNCLTVADDHDVQVMIHSDTLNESGFVEDTIKAFKGRTIHAFHTEGAGGGHAPDIIKVAGLENVLPSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRLGEVIIRTWQTADKMKKQRGSLSQDSARNDNFRVKRYIAKYTINPAIAHGVSKLIGSVETGKMADLVLWSPAFFGVKPDCIVKAGMIVAAPMGDPNASIPTPQPVHYQPMFGAYGRALTASSVVFTSQAAAAGHLARDLGIAKALYPVSNVRGGISKKSMIHNDATPNIEVDPETYEVRADGELLTCAPAEVLPMAQRYFMY
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VARA_VIOAR
Sequence: GLPVCGETCVGGTCNTPGCSCSWPVCTRN
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has cytotoxic activity against a variety of drug-resistant and drug-sensitive human tumor cell lines, and against primary chronic lymphocytic leukemia cells.  Has weak cytotoxic activity against primary ovarian carcinoma cells or normal lymphocytes.
What are the official names of this protein?
Varv peptide A.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: PACR_HUMAN
Sequence: MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT
What is the function of this protein?
This is a receptor for PACAP-27 and PACAP-38.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine.  May play a role in spermatogenesis and sperm motility.  Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
What are the official names of this protein?
Pituitary adenylate cyclase-activating polypeptide type I receptor, PACAP type I receptor, PACAP-R-1, PACAP-R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRI35_HUMAN
Sequence: MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYLGGARGAGPPEPLRICPLHISVKEELDG
What is the function of this protein?
E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response.  Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via RIG-I signaling pathway (PubMed:32562145).  Can also catalyze 'Lys-48'-linked polyubiquitination and proteasomal degradation of viral proteins such as influenza virus PB2 (PubMed:32562145).  Acts as a negative feedback regulator of TLR7- and TLR9-triggered signaling.  Mechanistically, promotes the 'Lys-48'-linked ubiquitination of IRF7 and induces its degradation via a proteasome-dependent pathway (PubMed:25907537).  Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (PubMed:25263439).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM35, Hemopoietic lineage switch protein 5.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies (By similarity).
Protein: HSP1_CHIMC
Sequence: MARYRCCRSQSRSRCRRRRRRCRTRRRRCCRRRRRRVCCRRYTVVRCRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYDND_SYMTH
Sequence: MKRTVYCGEVTDALVGQEVTVNGWVQRRRDHGSLIFVDLRDRTGLVQVVFDVEECGADLFRKAEQVRSEYVLAVRGRLVHRTPEAVNPNIPTGRFEIRALDLRILSPAKTPPFYIQDDLDVDETVRLKYRYLDLRRPEMQRNLILRHRVTKAVRDFFDEHGFLEIETPMLTKSTPEGARDYLVPSRVNPGKFYALPQSPQIFKQLCMVSGLERYVQIVRCFRDEDLRADRQPEFTQIDVEMSFVERDDVLSMMEQMVARVFRDALGVEVPTPFKRLTYAEAMARYGSDKPDLRFGMELVDVSDVAAGCGFGVFKGAVEAGGQVKGINAKGCGGYSRKQIDELTEFVKTYKAKGLAYIALGEGGEVRSSFTKFLTEAETAEIVRRLEGEPGDLLLFVADQPDVVAAALGALRVEMGNRLGLRKPGEFNLLWVIDFPLLEWDEEENRFVAVHHPFTSPHPEDLDKVFKEGATREELAAIRANAYDLVLNGVELGGGSIRIHQRPLQNRMFELLGFTPEEAQAKFGFLLEAFEYGAPPHGGIAFGLDRFVMLLAGRQSIRDVIAFPKTAKATDLMTDAPSEVAPKQLQELHIRTTV
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1614_METAC
Sequence: MDPQKPYKKELKRNSRKRSLNMSQNSERIRIIERDITELKVDAIVNAANNTLLGGGGVDGAIHRAAGPGLLEECRTLNGCPTGEAKITKGYLLPAKYVIHTVGPIWQEGTKGEDEFLASCYRKSLELARKYDVKTIAFPTISTGAYGFPSERAARIAVSQVKEFLKVNELPEIVFLVCYNKEACKNIKKALEENL
What are the official names of this protein?
Macro domain-containing protein MA_1614.
Protein: PSA1_RAT
Sequence: MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHVFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMQCNLDELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLEERPQRKAQPSQAADEPAEKADEPMEH
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit alpha type-1, Macropain subunit C2, Multicatalytic endopeptidase complex subunit C2, Proteasome component C2, Proteasome nu chain.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9.
Protein: GELS1_LUMTE
Sequence: MATGLIKAKEYDWKDSNLALFGSDTEKQVKKDSAATEPAWKGAGQKEGLKIWRIVNFKVTEWPQNQHGKFYNGDSYIILNTYKPDPKSNELAYDVHFWIGSQSSQDEYGTAAYKTVELDTFLDDKPVQHREVQGYESELFRNYFKQGLTILEGGAETGFHHVKPTEYKPRLLHFSGQKQQIYVHEVPLVKERLDHKDVFILDLGLTLYQWNGKESSKEEGFKAMQYLGLMRSERPKAEAETLEDESTPESHKFYTSLTGTDEPNLVKPLVKEENQLLKVSDAGGHLKTTEVKRGAVNSKDFSSNDVFILDTGDQCFVWVGKGRFAVGEAEWTRISHAHLMKTCHPLAPIHVIKEGQLCKAFNVAIAA
What is the function of this protein?
Calcium-regulated protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping).  Can promote the assembly of monomers into filaments (nucleation) as well as sever existing filaments.
What are the official names of this protein?
Gelsolin-like protein 1, Actin-modulator, EWAM, EWAM-P1.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MCU5_ARATH
Sequence: MWSVMGLVRRTAMSSTVNKASPVRSLLGGFRCLNVESKEEDEKKDMTVLEAKKLMRLVNVEDMKKKLIGMGDKEMVTYTTLIEASQGLGIARSLDEAHAFARVLDDAGVILIFRDKVYLHPHKVVDLIRKAVPLGLNPDDELIREEFDKMRSMKEEIDVLAHQQVRKILWGGLGYSVVQIGIFVRLTFWEFSWDVMEPITFFTTATGIIVGYAYFLMTSRDPTYQDFMKRLFLSRQRKLLKSHKFDAERFKELENKWKITSCSSSSCHANASIRNRVGVDLDLEDSLQSHHRD
What is the function of this protein?
Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria.  Constitutes a pore-forming and calcium-conducting subunit.  Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
What are the official names of this protein?
Calcium uniporter protein 5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the MCU (TC 1.A.77) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PANC_BURM7
Sequence: MKVISSIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDQYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIIAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLAQVRSAVLGGERDLAAIEQRALAHLAARGWKPDYVSIRRRANLVAPSAAHIEAGEPLVVLTAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_STAAE
Sequence: MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_GEOKA
Sequence: MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGKGGDVVFVVDEGLRTLMDFRYQRHFKAPRGENGMSKNQHGKNAEDLIVKVPPGTVVIDADTNEVLADLTEAGQRFVVAKGGRGGRGNTRFATASNPAPEIAENGEPGEERNIILELKLLADVGLVGFPSVGKSTLLSVVSAARPKIAEYHFTTLVPNLGVVETEDGRSFVMADLPGLIEGAHQGVGLGHQFLRHIERTRVIVHVIDMAAVEGRDPYNDYLVINEELKQYNLRLTERPQIVAANKMDMPNAEENLRRFKEKVGDAVPVFPISAATRQGVRELLFAIADLLETTPEFPLHEREDPAVQRVVYKYEKEEPPFTITRASDGAFILAGDKIEKLFKMTDFSREESVRRFARQLKAMGVDDALRERGAKDGDTIRLLDYEFEFVDDWDE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_CAUVC
Sequence: MTADPRLIVPLDLPTVDDARAMVERLGDAVSFYKIGLELLASDGMGLAHDLKASGKSIFLDWKLHDIGATVERSARVLATSGCDLLTVHAEPQVMQAAVKARGDSSLKILAVTVLTSLTDADLVEMGYAFTARDLVERRVRQALACGVDGIVSSPHEAALAREIANDAGQPEFLIVTPGVRPEWSAKNDQARAATPADALRAGATHLVCGRPITAANDPREAALKVVTEMAGI
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: TTCA_BURO0
Sequence: MNAPHMNDTAADAATLDDAAAPAGRPALTRREQKEAYENNKLFKRIVRQVGQAIGDYNMIEQGDKVMVCLSGGKDSYAMLDVLLRLRERAPIDFDIVAVNLDQKQPGFPEHVLPEYLKQVGVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRDDIVQTLLLNMFYGGKLKGMPPKLQSDDGKNIVIRPLAYVKETDLEKYAELREFPIIPCNLCGSQPNLKRAEMKALIRDWDKRFPGRVDNMFNALAKVVPSHLMDTTLYPFQSLRATGEADPQGDIAFDEEPCASGDDAAAPGAAQPISIVQFDDL
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
Protein: DMTA2_BOVIN
Sequence: MELRSELPSVPGAATAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRAPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGSSEAKLQKFDLFPKTLLQAGRPGSPQPQPGKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEAEASPAPGLGGGPGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPTVPPDKAAVGAVGAADDAWPGRVDAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSAAAAAVHKEPTYGGGLYGPMVNGAPEKQ
What is the function of this protein?
May be involved in sexual development.
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor A2, Doublesex- and mab-3-related transcription factor 5.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APGM2_ARCFU
Sequence: MKYLLLIPDGMADWEVEELDGRTPLEVAETENMDFLAKEGACGIAKTVPDGFEPGSDVANLTILGVDVRKHYTGRGPIEALARGVKGKLVFRCNLVKVEDGVMVDYSGGRISDEEARKVIEELNRAKPYDFVKFYAGKSYRNLLVINKDFRDDVKTFPPHDITGKEIDKHLPSGGELAELLKELMGWSAEILPEITDKANMIWPWGGGRMPSFPNFGQRYGLRGAMITEVDLLEGIARGMGMEVVQVEGITGYIDTNYRGLVRETARALEEHDFVVLHTEGIDEVGHEGDAELKVRAIELYDSKIVGKLLNKVDLDETRILLLPDHPTPVKVKTHVAEPVPFTLYGRGRDEVKVYTEKSCRRGKFGLVDGLRLMDLLIKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2, BPG-independent PGAM 2, Phosphoglyceromutase 2, aPGAM 2.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: THIM_SALAR
Sequence: MQPDLHCRTLAAHTLKHFRALSPLTHCMTNDVVQTFTANTLLALGASPAMVIDPAEARPFAAIANALLVNVGTLTASRADAMRAAVESAYDAKTPWTLDPVAVGALEFRRRFCLDLLSLRPAAIRGNASEILALAGMALGGRGVDTTEAALAALPAAQALARQIDCIVVVTGEIDYVTNGQRTLSIPGGDPLMTRIVGTGCALSAVVAASCALPGAALDNVASACCWMKLAGQAAAERSEGPGSFIPAFLDALYHLDVEAANATN
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: HNRH2_RAT
Sequence: MMLSTEGREGFVVKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMTMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSAGYGGGYGGQSSMSGYDQVLQENSSDYQSNLA
What is the function of this protein?
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm.  Binds poly(RG) (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein H2, hnRNP H2, Heterogeneous nuclear ribonucleoprotein H', hnRNP H'.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: UPPP_NITEC
Sequence: MDWLILIKAFLLGIVEGLTEFLPISSTGHLILAGDLLDFNDDKAQVFTVAIQLGAILSVCWEYRARLINVARGWGTRRANRFVLNLCVAFLPAAILGLLFIKTIKYYLFHPLPVAIALVTGGVLILWAERREHRIEVENVDDMNWKHALKIGCAQCLALIPGTSRSGATIIGGLLSGLSRKAAAEFSFFLAIPIMFAATFYDVYKHREFLHSDDLGMFVVGSIAAFISALIAIRGFIRYVSHHDFTLFAWYRIGFGLIVLLTAHFGLINWSAG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UXUA_BRUSI
Sequence: MRQAWRWFGPEAGVPLDAVRQAGATDIVSALHEVPIGQEWTSAQIVERKNLIESTPTGRHPLTWSVVESIPVSDDIKRSGKAARHDIGAWIASMEALARNDIKVICYNFMPVVDWCRTDLDYITSTGATAMRFDQDRFAAFDLHILQRKGAEKDYSEEDRIAARAIFEAMDETEIEQLIVNIASALPGSTTEPLTIPAFREKLETYASIDAAHLRRNLVEFLEAVTPVADSLGVKLTLHPDDPPRSLFGLPRIASTEADYAAIFAAVPAQSNGMCFCTGSLGVRADNDLPAIARRFASRIHFSHLRATTREGDGRTFHEAAHLEGDVDMVGILRILLEEDRKRDAGQTIIFRSDHGHRMMDDLEKKVTPGYPVIGRMRGLAELRGIITALDACALEYDPNV
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: IFNA2_MOUSE
Sequence: MARLCAFLVMLIVMSYWSICSLGCDLPHTYNLRNKRALKVLAQMRRLPFLSCLKDRQDFGFPLEKVDNQQIQKAQAIPVLRDLTQQTLNLFTSKASSAAWNATLLDSFCNDLHQQLNDLQTCLMQQVGVQEPPLTQEDALLAVRKYFHRITVYLREKKHSPCAWEVVRAEVWRALSSSVNLLPRLSEEKE
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.
What are the official names of this protein?
Interferon alpha-2, IFN-alpha-2.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_GRAFK
Sequence: MARYTGPKTKIARKFGEAIFGDDKSFEKRNYPPGQHGNNRRRGKKSEYAIQLMEKQKAKYTYGILERQFRNMFEKATRAQGITGEVLLQLCESRLDNVVYRMGVAPSRRAARQLVGHRHITVNGELVNIPSYHLKAGDVVGVREKSKSLAVVQESLSNNSSVYEWISWNSEKKEGTFVAVPGRVQIPENINEQFIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: UPPP_SYNE7
Sequence: MLIAVSSADRLDLWQAIVLGFVQGATEFLPISSTAHLKVVPVVLGWGDPGVAFTAVIQLGSIVAVLSYFRQDLTYVLRGLVSAVRRQDFRSEPAQMGLGILFGTIPILIGGLLIKRFIPDYDNSPLRSLAAIAIVSIVMGLLLGIAEQLSKHQRDLSQLRLADGLWMGFAQALALIPGVSRSGSTLTAGLFQGLKRDTAARFSFLLGIPAITIAGLVELKDLLEAGIDGSSLGVLAIGTLSSLIFSWLAIAWLLRFLRTHNTWSFVVYRIIFGGVILTAIATGTLQNI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTS_SODGM
Sequence: MIDTKNLDSHTPMMQQYLKLKAQHPDILLFYRMGDFYELFYDDAKRASQLMDISLTKRGASAGQPIPMAGVPYHAVENYLAKLVALGESVAICEQIGDPATTKGPVERRVVRIVTPGTLSDEALLNERQDNLLAALWQAPQGFGYATLDITSGRFLVSEPADREAMAAELQRTNPAELLYPETLQDMKLIEHRRGQRRRPLWEFELDTARQQLTLQFGTRDLNGFGIERAQLALRAAGCLLQYAKDTQRTSLPHIRAVTLELQQDGIVMDAATRRNLELTQNLSGGGENTLADVLDRTVTPMGSRMLKRWLHMPTRDITTLTYRQQSIRALQDHVAELQPLLRQVGDLERVLARLALRSARPRDLARMRYAFTQLPAIQALLCGQSEPYLPQLLDRVGEFETLRDLLARAIIEAPPVLVRDGGVIAPGYHAELDEWRGLAAGATDYLDRLELREREKTGLETLKVGFNAVHGYFIQLSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKSKALALEKALYDELFDLLLPHLAALQQSATALAELDVLSNLAERAETLRYVCPTIDARQGIHISGGRHPVVEHVLSEPFIANPLTLSDARRMLIITGPNMGGKSTYMRQTALIVLLAYIGSFVPADEATIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATHQSLVLMDEIGRGTSTYDGLSLAWASAESLAGRIKAMTLFATHYFELTTLPEKMEGVVNVHLDAVEHGDTIAFMHSVQEGAASKSYGLSVAALAGVPREVIKRARQKLRELETLSTGAAAGSVDGSQLSLLQPEEQPVAPAVEALENLDPDSLSPRQALEWLYRLKKML
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: HSCB_YERPS
Sequence: MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQTLKHPLKRAEYMLSLQGFDLGNEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSRRLAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQQVEQLEERLFDDFA
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.