PharMolix/UniProtQA huggingface dataset:
Protein: RL25_ORITB
Sequence: MNEMLTLVGQLRSDFGTSSARALRRQGKVPGVIYKKGITPIHVCTLEKEVAKLYRKPFFSSTVIQLQVDDQRFKVLPKAVQLHPVTEFMNHIDFILVEQNGSMQKVKVPISFEGKEKSLGIKRGGYLNIVKRYVDLLCPVDKIPQCIKCDIANVSVGASIKISRLELPEGCNLVKSTTDYVIASVIGKSSKQDKEEEGTAEDGADSK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: SHO1_OGAPD
Sequence: MGRSNPVSLFNPFALSTFGFSSIGWIITFAGCIATNTQNNGFPKFAWWAVVFQLLLLIVIVVLYITNTFHYHRFFLTCAIGVAFVYNSNATNNLVYDTSSAPAAASAGFIIQCIVNILWLFYFGSEPSSPIISYIDSFGSSENVMLSSKRSKSNRNAAGQSQIPLDEPYKDETMGYAERNSVSNDNSGLHENPFNTQNYTAQLSGLENASTTNRASALPEDDYPITVRGLFDYDASPDDINELSFKKGDIFRVKDTVGNWWQGKNSKGEIGMCPSNYLEVIG
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEPA_XANOP
Sequence: MRNIRNFSIIAHVDHGKSTLADRIIQLCGGLQAREMEAQVLDSNPIERERGITIKAQSVSLPYTAKDGQVYHLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQSVANCYTAVEQGLEVVPVLNKIDLPTADVDRAKAEIEAVIGIDAEDAVAVSAKTGLNIDLVLEAIVHRIPPPTPRDTDKLQALIIDSWFDNYLGVVSLVRVMQGEIKPGSKILVMSTGRTHLVDKVGVFTPKRKELSALGAGEVGWINASIKDVHGAPVGDTLTLAADPAPHALPGFQEMQPRVFAGLFPVDAEDYPDLREALDKLRLNDAALRFEPESSEAMGFGFRCGFLGMLHMEIVQERLEREYNLNLISTAPTVVYEVLKTDGSVIPMDNPSKLPPLNNVEEIREPIIRANILTPPDYVGNIITLCEEKRGSQIGINYLGSQVQISYELPMAEVVLDFFDKLKSVSRGYASLDYHFLRFDPGPFVRVDTLINGDKVDALSIIVHRSYADRRGRELCEKMKDLIPRQMFDVAIQAAVGSQIISRSTVKAMRKNVLAKCYGGDVSRKKKLLEKQKEGKKRMKQVGRVEIPQEAFLAVLQMDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SUCC_PSEAE
Sequence: MNLHEYQGKQLFAEYGLPVSKGFAVDTPEEAAEACDKIGGSEWVVKAQVHAGGRGKAGGVKLVKSKEDAKAFAQQWLGKNLVTYQTDANGQPVSKILVESCTDIDKELYLGAVVDRSSRRIVFMASTEGGVDIEKVAHDTPEKILKATIDPLVGAQPYQGRELAFQLGLKGDQIKQFTHIFVGLAKLFQDYDLALLEVNPLVIKKDGNLHCLDAKINIDSNALYRQPKLRAMHDPSQDDAREAHAQKWELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.  Can also generate UTP or CTP, although it preferentially synthesizes ATP and/or GTP.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: QSEF_ECO57
Sequence: MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRVLNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFSFLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSVLINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVSNREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDINVRIISATHRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVRAFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFVEARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE
What is the function of this protein?
Member of the two-component regulatory system QseF/QseE involved in the regulation of virulence and metabolism in EHEC.  Required for pedestal formation in host epithelial cells during infection.  Regulates various metabolic and virulence genes, many iron-utilization genes and some two-component systems such as RcsB/RcsC and PhoP/PhoQ.  Activates, indirectly, transcription of EspF(U) to induce pedestal formation.
What are the official names of this protein?
Transcriptional regulatory protein QseF, Quorum-sensing regulator protein F.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP1_PLAGI
Sequence: MARCRRHSRSRSRSRNQCQRRRRRHYNRRRTYRRSRRHSRRRRVRRRGCSCRRCSRRRRRRC
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: BR1_RANTE
Sequence: VNPIILGVLPKFVCLITKKC
What is the function of this protein?
Antibacterial activity against representative Gram-negative and Gram-positive bacteria and exhibits a very high hemolytic activity.
What are the official names of this protein?
Brevinin-1T.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: PYRG_GRABC
Sequence: MTRFVFITGGVVSSLGKGIASAALGALLQARGYSVRLRKLDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGVHARKSDNATTGRIYSDVIARERRGDYLGATVQVIPHITDAIKDAVTRDLNQDLDFALIEIGGTVGDIESLPFLEAIRQLGNELGPSRTMFVHLTLVPYIPSAGELKTKPTQHSVKELQNVGIQPNMLLCRCDRLIPENERRKIANFCNVRQEAVVSALDVDTIYSVPIRYHEEGMDREVLRHFNLPIGGEPDLTRWREIADVVRAPDGVVKIAIVGKYITLLDSYKSLAEALVHGGIANRVKVEIDWVDSQIFEQADSVQRLEGVHGILVPGGFGERGAEGKIEAVRFAREHKVPFLGICFGMQMAVIEAARNLAGLPDASSTEFGPCEVPIVGLMTEWARGNDLERRSASGDLGGTMRLGSYPAALIEGSLARETYGGVPVVQERHRHRYEVNIHYREQLEAVGLRFSGLSPDGVLPEIVEYADHPWFVGVQYHPELKSKPFDPHPLFSGFVAAAVRQARLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RLMG_YERE8
Sequence: MSQVLLGTQSFELERFPPQENSNTLQAWEAADEYLLQNIDLNQIDGRPVLVFNDQFGTLTCALHAYRPFSVSDSYMSQLATAHNLRLNHLDEDVVTLLSSMDALPEAPKLVVIKIPKALALLEHQLRALRRVVAPDTVIIAGAKSRDVHNSTLQLFEKILGPTKTTLAWKKARLIHCEVADIPLAEEAPETVDWPLANTEYVIHNHANVFSRNNLDIGARFFMEILPYDVEGKIADLGCGNGVVGLIALEQNPLAEMLFVDESYMAVASSELNITYNRPQDLSRCEFMVSHGLAGVERESLQLVLCNPPFHQQHAVSDHVAWQMFCDAKRCLKVGGELMIVGNRHLDYFHKLKRLFGNCETLDSNQKFMVLKAVKTASSRSEGGGSGSLDMSYSDF
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_MYCTA
Sequence: MTVLNRTDTLVDELTADITNTPLGYGGVDGDERWAAEIRRLAHLRGATVLAHNYQLPAIQDVADHVGDSLALSRVAAEAPEDTIVFCGVHFMAETAKILSPHKTVLIPDQRAGCSLADSITPDELRAWKDEHPGAVVVSYVNTTAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQFLGAHVRRVTGRKNLHVWAGECHVHAGINGDELADQARAHPDAELFVHPECGCATSALYLAGEGAFPAERVKILSTGGMLEAAHTTRARQVLVATEVGMLHQLRRAAPEVDFRAVNDRASCKYMKMITPAALLRCLVEGADEVHVDPGIAASGRRSVQRMIEIGHPGGGE
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN784_MOUSE
Sequence: MAAARPDPPIPSSPTRESPSPEPPDLVLVPDGRPVTPPGDLIEIQVVKVTDTTSVPEPPEPGSFHCALCPAAFRLVSELLFHEHGHLASMEGLGQDGDPSRCHVCGHSCPGPASLRAHYSLHTGERPYRCSLCPRAFKALAPLLRHQHRHGVEPGTSERLLPTTTTGQPNSRVAQERSEVVMAAAAAGAVVGKPFACRFCAKPFRRSSDMRDHERVHTGERPYHCSICGKGFTQSSVLSGHARIHTGERPFRCMLCDRTFNNSSNFRKHQRTHFHGPGSGVGESRGQLRSSSVSQES
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 784.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAA_ECO7I
Sequence: MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPO_NANGA
Sequence: MGVPDCLALPLLVTFLLLSLGLPVLGAPPRLICDSRVLERYILEAKEAENITMGCAEGPRFNENFTVPDTKVNFYAWKTMGVEEQAVEVWQGLSLLFEAILRAQAVLANSSQPSEMLQLHVDKAISGLRSLTSLLRALGAQKEAISPPDTTQVIPLRRFTVDTFCKLFRIYSNFLRGKLKLYTGEACRRGDR
What is the function of this protein?
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass.  Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
What are the official names of this protein?
Erythropoietin.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y487_HAEIN
Sequence: MRLFKQLERWKIRRQINQSIIDVIFRLRDRLAHYWQADVNTPQVDFMLLHIACSLGRIERGGCVSSLYSEMLEEMQSAVIFPQVLAIHQDLLKLMPFSIPEAEQTYFLANIHSLVLEQKQLKPLK
What are the official names of this protein?
Uncharacterized protein HI_0487.
Protein: ARMET_DROPE
Sequence: MKTTHLVLVLCFLAGVAQTTLALKEEDCEVCIKTVRRFAASLDDAIKGDYKQIETEFKKFCKTQKNKEHRFCYYLGGLEESATGILNEMSKPLSWSMPAEKVCEKLKKKDAQICDLRYEKQIDLNSVDLKKLKVRDLKKILNDWDESCDGCLEKSDFIKRIEELKPKYARSEL
What is the function of this protein?
Required during the maturation of the embryonic nervous system for maintenance of neuronal and cuticular connectivity.  Essential for maintenance of dopaminergic neurons and dopamine levels (By similarity).
What are the official names of this protein?
Mesencephalic astrocyte-derived neurotrophic factor homolog, MANF/CDNF-like protein.
What is the protein family that this protein belongs to?
Belongs to the ARMET family.
What are the subcellular locations of this protein?
Secreted.
Protein: CD19_CAVPO
Sequence: NSSDLGDFSCGPGNGSSEGPTPSSQHPNSSQLYVWDKRDSPSWEPEPVCAPPRGSLNENLTQDLTVALGSTLWLSCGVPPAHVTRGPVSWTQVHPKKPDSTLLSLYLREKPPVQEMWVLGPVLSLSQVTVQAAGTYYCLRGNLTTEIHMKVTARQAVWHWLLRSGGWKVPAVSLVYLIFCLGSLVVFLQIRKALVLRRKRKRMTDPNRRFFKVTPPSGNGTPNQYGNVLSLPTPGSSTGRTQRWAAALGGTIQSYGNSRSDVQETGAMGSRSPTTAGIEEEEGEGYEEPDSEEGSEFYENDSNRGQDQLSQDASGYENPEDGPLGSADEDSFSNESYENADEELAQPVARTTDFLSPHGSAWDPSREATSLGSQSYEDMRGILYAAPQLRSLQPGPHHEEDADSYENMDNPDEPEPAWGGGGHMGIWSTR
What is the function of this protein?
Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes.  Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity).  Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores.  Is not required for early steps during B cell differentiation in the blood marrow.  Required for normal differentiation of B-1 cells.  Required for normal B cell differentiation and proliferation in response to antigen challenges.  Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge (By similarity).
What are the official names of this protein?
B-lymphocyte antigen CD19, Differentiation antigen CD19.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein.
Protein: RR1_SPIOL
Sequence: MASLAQQLAGGLRCPPLSNSNLSKPFSPKHTLKPRFSPIVSAVAVSNAQTRERQKLKQLFEDAYERCRNAPMEGVSFTIDDFHTALDKYDFNSEMGSRVKGTVFCTDANGALVDITAKSSAYLPLAEACIYRIKNVEEAGIIPGVREEFVIIGENEADDSLILSLRQIQYELAWERCRQLQAEDVVVKGKIVGANKGGVVALVEGLRGFVPFSQISSKSSAEELLEKEIPLKFVEVDEEQSRLVMSNRKAMADSQAQLGIGSVVTGTVQSLKPYGAFIDIGGINGLLHVSQISHDRVSDIATVLQPGDTLKVMILSHDRERGRVSLSTKKLEPTPGDMIRNPKLVFEKAEEMAQTFRQRIAQAEAMARADMLRFQPESGLTLSSDGILGPLTSDLPAEGLDLSVVPPAVES
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus (PubMed:10874039, PubMed:28007896).  Actively engaged in the initiation complex formation via a strong mRNA-binding activity.  Possesses a poly(A)-binding activity which might play a role as a control element in chloroplast mRNA translation (PubMed:1527032).
What are the official names of this protein?
30S ribosomal protein S1, chloroplastic, CS1, Chloroplastic small ribosomal subunit protein bS1c.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFTU2_SHISS
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLS
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_PHOPR
Sequence: MLSKLLTKVIGSRNDRTLRRMRKIVDEINKLEPQFDSLQDEDLKAKTVEFRERLDQGESLDLLLPEAFATVREASKRVFGMRHFDVQLLGGMVLNNCQIAEMRTGEGKTLTATLPAYLNALTGKGVHIVTVNDYLAARDAETNRALFEFLGMTVGINVPNMPPQAKKEAYSADVLYGTNNEFGFDYLRDNMAFRPEDRVQRERFFAVVDEVDSILIDEARTPLIISGPAEDSSDLYTRINLLIPQLVKQDQEDSEDFRGDGHYTVDEKSKQTHLTENGQEFVEELLTQQGMMAEDDTLYSPSNISLLHHITAALRAHVLFERDVDYIVKDDEVIIVDEHTGRTMPGRRWSEGLHQAVEAKEGVKIQNENQTLASITFQNYFRLYSKLSGMTGTADTEAFEFQSIYGLETVVMPTNKPMVRDDMGDLVYMTEAEKFAAICEDIKERFAKGQPVLVGTVSIEKSELLSNALKKEGIKHEVLNAKFHEKEAYIIANAGQSGAVTIATNMAGRGTDIVLGGSWQEEISNLQDPTDAQIAQIKVDWKVRHETVLAAGGLHITGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDGLMRIFASDRVSNMMKKLGMEEGEAIEHPWVTKAIENAQRKVEGRNFDIRKQLLEFDDVANDQRQVVYELRDELMNADDISGMITQNRDDVILAVVDTYIPQQSLEEMWDIKGLEERLKADFDLELPIQEWLDTEEKLYEEALRERIVAKAIEVYQQKEEVVGAEVLRNFEKTVMLQNLDTLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFEEMLDSLKSDVVSILSKVRVQQQEEVDRMEEERRQQAEELARRQQYQHQNAASQIADESDAGQPAESGTFEREARKVGRNEPCPCGSGKKYKQCHGKIN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: ADEC_BORBU
Sequence: MDLFKIEANYIDIFNKEIYPASIAIANGHIASIEKINATLDEYVLPGFIDAHIHIESSFLVPSNFAHLVVAHGTVATISDPHEIANVNGIDGINFMINNSKKTEFKFFFGAPSCVPALSQEFETSGYVLNDKDIDELMKLDDIYYLAEVMDFKGVINKDIEIINKINSALKRNKVVDGHAPGLSPNLTLKYASSGISTDHECLTIEDARYKLSLGMKILIREGSAAKNFESLHPLISECSKKYCDSLMFCFDDAHPNDILNGHINLIVARAIKHGHDFFDVLKIACINPVLHYKIPVGLLRIGDPADFIITKDIKTFKINKTYINGKLVFNDGISLIPLINEIPINNFNCSKKSISDFKFSTKNKMIPVIKCISNQIITHKTMIDSNLLAPDFQSNIAEDILKIAIINRYKDNSKISIGFIKNFGIRNGAIGSTVAHDSHNIILVGSNDEYLCKAANTIIQNKGGLCALNNEKTIIMELPISGLMSTLSAERVASQYIKLNDFCKNVLGSRLDDPLMTLSFMSLTVVPHLKINDKGLFDVDSFCFVDY
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: ATPB_FLAJ1
Sequence: MSKVIGKVAQIIGPVVDVVFNGKDVELPKIYDSLEVTKKDGTLLVLEVQSHIGENTVRTISMDSTDGLSRGYEVVGTGNPIQMPIGPDVYGRLFNVVGDAIDGLGNLPKTGENGLPIHRQAPKFEDLSTSSEVLFTGIKVIDLIEPYAKGGKIGLFGGAGVGKTVLIQELINNIAKGHGGLSVFAGVGERTREGNDLLREMLESGIIKYGDDFMHSMENGGWDLSKVDMPGMRESKATFVFGQMNEPPGARARVALSGLSIAEYFRDGAGSDQGKDVLFFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGAMQERITSTNKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRKIAELGIYPAVDPLDSTSRILTPHILGDEHYNCAQRVKEILQKYKQLQDIIAILGMEELSEEDKLSVSRARRVQRFLSQPFHVAEQFTGIPGVLVDIKDTIKGFNMIIDGELDHLPEAAFNLKGSIQDAIEAGEKMLAEA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RBFA_ACICJ
Sequence: MLRDRNRSGVRGGAEGPSQRQRRVAEDLRHRLAELFARTEFRDPELAGVHITVAEVRMSPDLKHATVFVSRLGATDIDRYLPALKRIAPFLRGEIGHGLRMKFVPDLHFQPDHALDEATRINELLHRPEVMRDLLKPDEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_HYPNA
Sequence: MKAADVRSKSVDQLSDELVKLKKEQFNLRFQAATGQLEKTGRVTEVRRDIARVKTILREKSQAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: MGT4D_HUMAN
Sequence: MRTKQVNLLITLVAVALFSFSCFSIYRITQTNNQLINCRNHILEFKENMLHLRNKTEKNTQEMMKVLNRMKYEITKREILSGNLVAQKADILNKNETVSNTFEDLKFFFPHLRKEGRIYPDVIIGKGKTGVSFALGISTVNRGNYSYLKQTLTSVVSRMTLSQEKDSVVIVLVADSNEDYLHSVVKMITKKFKRQVRSGSLEVISIPAFLYSSMLNAKHLAEASQKLASWRIKQVLDFCILLLYAQPKAKYYLQLEDDIIAKEMYFTKITDFVGNISSNNWFFIEFSMLGFIGKLFRSEDLTHFVRFFLMFYKEKPIDWLLNDIFQVKVCDAGEDLRNCMKRKKQIRIQYKPSLFQHVGIHSSFPRKEQYEKKI
What is the function of this protein?
May play a role in male spermatogenesis.  In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans.  The function is mediated by its lumenal domain and occurs specifically in the Golgi.  A catalytic glucosyltransferase activity is not detected.  May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.
What are the official names of this protein?
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D, N-acetylglucosaminyltransferase MGAT1 inhibitory protein, GlcNAcT-I inhibitory protein, GnT1IP.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: NADE_STAAC
Sequence: MSKLQDVIVQEMKVKKRIDSAEEIMELKQFIKNYVQSHSFIKSLVLGISGGQDSTLVGKLVQMSVNELREEGIDCTFIAVKLPYGVQKDADEVEQALRFIEPDEIVTVNIKPAVDQSVQSLKEAGIVLTDFQKGNEKARERMKVQFSIASNRQGIVVGTDHSAENITGFYTKYGDGAADIAPIFGLNKRQGRQLLAYLGAPKELYEKTPTADLEDDKPQLPDEDALGVTYEAIDNYLEGKPVTPEEQKVIENHYIRNAHKRELAYTRYTWPKS
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RSMG_YERPP
Sequence: MLKKLDSLLTVAGITLPDQQKHQLIGYVELLDKWNKAYNLTSVRDPQQMLVRHILDSIVVNPHLQGSRFIDVGTGPGLPGIPLAIVRPDAHFTLLDSLGKRVRFLRQVQHELGLNNIEPVQSRVEAFTSEPPFDGVISRAFASLQDMLSWCHHLPAKPEGRFYALKGVRPDDELAVLPEDIVLESVIKLDVPELDGERHLIILKSN
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_PSEE4
Sequence: MVFFPELEQARLLRRYKRFLADIELANGEQLTIHCPNTGSMLNCMREGGQVWFSRSNDPKRKLPGTWEISETPQGRLACVNTGRANALVEEALRAGTILELAGFELLKREVAYGEERSRIDFYLEFADGRPAYVEVKSVTLGFPDTPVAAFPDAVTQRGAKHLRELAALARQGIRAVQLYCVNLTGIEAVRPAEEIDAAYAQALRAAVAEGVEVLAYGTRLDARGIVIDRPLPVLLNP
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.