PharMolix/UniProtQA huggingface dataset:
Protein: A4177_ARTBC
Sequence: MDGFNPRATTVAEYMDGTPKFRTDLYASTCGQLLSHKEYMRVVDMYGLKFTPELKAPEVPMPFMGKYSQEQYAQQLIDEYRAARISPDRVFLQSFSIDDIYFWNRHDADYARQAMFLDSRPDTPEGARQATATMAQLKQSGIRTLSPAFHALLKLDAGNNIVPSDYAVAAKKAGIKLTTWSLERSGPLNKVRASGDFYYSSIAAAIKDDGDIYRVVDVLAQKVGVAGIFSDWPATVSFYANCFNL
What are the official names of this protein?
Extracellular protein ARB_04177.
What are the subcellular locations of this protein?
Secreted.
Protein: TAL1_BACAN
Sequence: MKFFIDTANINEIKEANALGVLAGVTTNPSLVAKEGVDFHERIREICNVVEGPVSAEVISLEADKMIEEGKELAKIAPNVVVKVPMTTEGLKAVKAFSDLGIRTNVTLVFSAVQALLAARAGATYVSPFLGRLDDIGHNGMDLIRQIAEIFAIHGIETEIIAASVRHSVHVTDAALNGAHIATIPANVIASLVKHPLTDQGIEKFLADWEKTQEK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase 1.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1902_STAA3
Sequence: MTNGYIGSYTKKNGKGIYRFELNENQSRIDLLETGFELEASTYLVRNNEVLYGINKEGEQCGVASLKIDDNGELHLLNKCLSSKAGTGCYVSISEDKRYLFEAVYGAGIIRMYELNTHTGEIIRLIQELAHDFPTGTHERQDHPHAHYINQTPDGKYVAVTDLGADRIVTYKFDDNGFEFYKESLFKDSDGTRHIEFHDNGKFAYVVHELSNTVSVAEYNDGKFEELERHLTIPENFDGDTKLAAVRLSHDQQFLYVSNRGHDSIAIFKVLDNGQHLELVTITESGGQFPRDFNIASSDDLLVCAHEQGDSVVTVFERNKETGKITLCDNTRVASEGVCVIF
What are the official names of this protein?
Uncharacterized protein SAUSA300_1902.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: AT17_ACTDE
Sequence: MASFPPSLVFTVRRKEPTLVLPSKPTPRELKQLSDIDDQEGFRFQVPVIMFYKRKLYMEGEDPVKVIREALAEALVFYYPFAGRLIEGPNRKLVVDCTSEGVLFIEADADIELNQLIGDTIDPGTYLDELLHDVPGSEGIVGCPLLLIQVTRFRCGGWAFAIRLNHTMSDTLGLVQFLTTIAEFTRGAEDAPSVPPVWQREFLAARQPPFIPFQHHEYEQVIDTIPDDNKKSMTHKSFFFGPKEIRAIRSHLPHHHRSTSSTFDVLTACLWRCRTCALGLDPQMTVRISCAANGRGKHGLHVPRGYYGNVSAFPATVLRAGIISTSPLEYAMEGVKKAKAIMTGEYLRSVADLMVTKGRPRYTVAGNYIVSDMTRVGLDTIDFGWGKPVYGGPARAFPLISFYGRFKDNKGEDGTVVLICLPEAALERFQEELKKMTGEHVDGPFDYKPIKVVSKL
What is the function of this protein?
Involved in the biosynthesis of volatile esters which confer kiwifruit flavor (By similarity).  Alcohol acyl transferase that can use a wide range of alcohols as substrate to produce esters (By similarity).
What are the official names of this protein?
Alcohol acyltransferase 17, AdAT17.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: COX2_LYCGY
Sequence: MAYPFQLGLQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKPGELRLLEVDNRVVLPMEMTVRMLISSEDVLHSWRVPSLGLKTDAIPGRLNQTTLMAMRPGLYYGQYSEICGSNHSFMPIVLEMVPLSYFETWSAVMV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL2_THEAB
Sequence: MGLRRFKPTSPARRQMIIPDFSEITKKEPEKSLIAPLKKTGGRNSYGRVTVRFRGGGHKRRYRIIDFKRDKVGIPARVVSIEYDPNRTARIALLVYADGEKRYILAPQGLNVGDTVLNGPDAEIKPGNALPLENIPVGTIVHNVEFIPGKGGQIARSAGTSCQLMAKEGKYALLRMPSGELRKVPVKCYATIGVVGNEDHKNEVDGKAGRVRWKGRKPHVRGVAMNPVDHPHGGGEGRGKGHHPQSPWGQLAKGYKTRRGKKASDKLIVRRRNG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: VATG1_HUMAN
Sequence: MASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSRGSCSTEVEKETQEKMTILQTYFRQNRDEVLDNLLAFVCDIRPEIHENYRING
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002, PubMed:32001091).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32001091).  In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).
What are the official names of this protein?
V-type proton ATPase subunit G 1, V-ATPase subunit G 1, V-ATPase 13 kDa subunit 1, Vacuolar proton pump subunit G 1, Vacuolar proton pump subunit M16.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase G subunit family.
What are the subcellular locations of this protein?
Apical cell membrane.
Protein: ISPE_MYCMM
Sequence: MSRTSDGNTAELWVPTGSATVRVPGKVNLYLAVGDRRDDGYHELTTVFHAVSLVDEVTVRNADLLSLEVVGEGADRLPTDKRNLAWQAAELMAEHVGRAPDVSIFIDKSIPVAGGMAGGSADAAAVLVAMNSLWELNLPRRDLRMLAARLGSDVPFALHGGTALGTGRGEELATVLSRNTFHWVLAFARSGLSTPAVFTELDRLRDVGSPPRLAEPGPVLAALAAGDPEQLAPLLGNEMQAAAVSLDPALRRALRAGVEAGALAGIVSGSGPTCAFLCRTAESALDVSAQLSGAGVCRTVRIATGPVPGARVVPTPGIAE
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PUB3_ARATH
Sequence: MDPVPVRCLLNSISRYLHLVACQTIRFNPIQTCIGNMVLLLKLLKPLLDEVVDCKIPSDDCLYKGCEDLDSVVNQAREFLEDWSPKLSKLFGVFQCEVLLGKVQTCSLEISRILLQLSQSSPVTSSVQSVERCVQETESFKQEGTLMELMENALRNQKDDITSLDNNHLESIIQMLGLISNQDLLKESITVEKERIRSQASKSEEDMEQTEQLIELVLCIREHMLKTEFLEVAKGISIPPYFRCPLSTELMLDPVIVASGQTFDRTSIKKWLDNGLAVCPRTRQVLTHQELIPNYTVKAMIASWLEANRINLATNSCHQYDGGDASSMANNMGSQDFNRTESFRFSLRSSSLTSRSSLETGNGFEKLKINVSASLCGESQSKDLEIFELLSPGQSYTHSRSESVCSVVSSVDYVPSVTHETESILGNHQSSSEMSPKKNLESSNNVNHEHSAAKTYECSVHDLDDSGTMTTSHTIKLVEDLKSGSNKVKTAAAAEIRHLTINSIENRVHIGRCGAITPLLSLLYSEEKLTQEHAVTALLNLSISELNKAMIVEVGAIEPLVHVLNTGNDRAKENSAASLFSLSVLQVNRERIGQSNAAIQALVNLLGKGTFRGKKDAASALFNLSITHDNKARIVQAKAVKYLVELLDPDLEMVDKAVALLANLSAVGEGRQAIVREGGIPLLVETVDLGSQRGKENAASVLLQLCLNSPKFCTLVLQEGAIPPLVALSQSGTQRAKEKAQQLLSHFRNQRDARMKKGRS
What is the function of this protein?
Functions as an E3 ubiquitin ligase.
What are the official names of this protein?
U-box domain-containing protein 3, Plant U-box protein 3, RING-type E3 ubiquitin transferase PUB3.
Protein: FLP_YEAST
Sequence: MPQFGILCKTPPKVLVRQFVERFERPSGEKIALCAAELTYLCWMITHNGTAIKRATFMSYNTIISNSLSFDIVNKSLQFKYKTQKATILEASLKKLIPAWEFTIIPYYGQKHQSDITDIVSSLQLQFESSEEADKGNSHSKKMLKALLSEGESIWEITEKILNSFEYTSRFTKTKTLYQFLFLATFINCGRFSDIKNVDPKSFKLVQNKYLGVIIQCLVTETKTSVSRHIYFFSARGRIDPLVYLDEFLRNSEPVLKRVNRTGNSSSNKQEYQLLKDNLVRSYNKALKKNAPYSIFAIKNGPKSHIGRHLMTSFLSMKGLTELTNVVGNWSDKRASAVARTTYTHQITAIPDHYFALVSRYYAYDPISKEMIALKDETNPIEEWQHIEQLKGSAEGSIRYPAWNGIISQEVLDYLSSYINRRI
What is the function of this protein?
Part of the plasmid amplification system, which corrects any decrease in copy number caused by a rare missegregation event.  Catalyzes the recombination between the large inverted repetitions of the 2-micron plasmid during plasmid replication.  This recombination event changes the direction of one of the two replication forks in the bidirectionally replicating molecule, effectively resulting in multiple rounds of replication from a single initiation event.  Binds specifically to the FLP recognition target (FRT) site where it induces DNA to bend.  Three types of bend exist.  Type I is approximately 60 degrees and results from 1 FLP molecule binding to 1 symmetry element.  Type II is >144 degrees and results from FLP molecules binding to symmetry elements a and b.  Type III is approximately 65 degrees and results from FLP molecules binding to symmetry elements b and c.
What are the official names of this protein?
Site-specific recombinase Flp, FLP, Protein Able.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: B3GTF_ARATH
Sequence: MKRFYGGLLVVSMCMFLTVYRYVDLNTPVEKPYITAAASVVVTPNTTLPMEWLRITLPDFMKEARNTQEAISGDDIAVVSGLFVEQNVSKEEREPLLTWNRLESLVDNAQSLVNGVDAIKEAGIVWESLVSAVEAKKLVDVNENQTRKGKEELCPQFLSKMNATEADGSSLKLQIPCGLTQGSSITVIGIPDGLVGSFRIDLTGQPLPGEPDPPIIVHYNVRLLGDKSTEDPVIVQNSWTASQDWGAEERCPKFDPDMNKKVDDLDECNKMVGGEINRTSSTSLQSNTSRGVPVAREASKHEKYFPFKQGFLSVATLRVGTEGMQMTVDGKHITSFAFRDTLEPWLVSEIRITGDFRLISILASGLPTSEESEHVVDLEALKSPTLSPLRPLDLVIGVFSTANNFKRRMAVRRTWMQYDDVRSGRVAVRFFVGLHKSPLVNLELWNEARTYGDVQLMPFVDYYSLISWKTLAICIFGTEVDSAKFIMKTDDDAFVRVDEVLLSLSMTNNTRGLIYGLINSDSQPIRNPDSKWYISYEEWPEEKYPPWAHGPGYIVSRDIAESVGKLFKEGNLKMFKLEDVAMGIWIAELTKHGLEPHYENDGRIISDGCKDGYVVAHYQSPAEMTCLWRKYQETKRSLCCREW
What is the function of this protein?
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue.  Involved in the biosynthesis of N-glycans containing Lewis a structures (with the combination of FUT13).
What are the official names of this protein?
Beta-1,3-galactosyltransferase GALT1, Beta-1,3-galactosyltransferase 15, Galactosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: MO2B2_AEDAE
Sequence: MNYLKLTFDKLEVGEINDLVAHESCGAISLFVGTTRDNFDGKTVVLLEYEAYEAMALKTMNQICEELRARWPDIKHIGIHHRLGTVPVKEASVVIAVSSPHRKSSLEAVHFAIDELKKSVPVWKKEQYAEGEGCSEWKENKECSWSKSHRDNHIL
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit 2, Molybdenum cofactor synthesis protein 2 large subunit 2, Molybdenum cofactor synthesis protein 2B 2, MOCS2B 2.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_YERPN
Sequence: MSKVLVLKSSILATSSQSNQLADFFVEQWQAAHAGDQITVRDLAAQPIPVLDGELVGALRPSGTALTPRQQEALALSDELIAELQANDVIVIAAPMYNFNIPTQLKNYFDMIARAGVTFRYTEKGPEGLVTGKRAIILTSRGGIHKDTPTDLVVPYLRLFLGFIGITDVEFVFAEGIAYGPEVATKAQADAKTLLAQVVAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RS3_MANSE
Sequence: MAVNNISKKRKFVGDGVFKAELNEFLTRELAEDGYSGVEVRVTPTRSEIIIMATRTQSVLGEKGRRIRELTSVVQKRFNIPEQSVELYAEKVATRGLCAIAQAESLRYKLIGGLAVRRACYGVLRFIMESGARGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPCNDYVNTATRHVLLRQGVLGIKVKIMLPWDQQGKNGPKKPQPDHILVTEPKDEPAPLEPTSDIRSLAPAPLPQPVAAVA
What are the official names of this protein?
40S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RADA_DEIRA
Sequence: MERVAVLFRRTCNSENCSKGRRPLRERPLAGLFFCSLPAPLSIPCLSLPGSNPGDFVPKVKTNYICNSCGYQSAKPLGRCPNCQAWNSFEEEVPTASTSGKSGRGGLGGYGGVKGGKLTPLSTVGRREEPRTPSGIPELDRVLGGGLVAGGVTLIGGEPGIGKSTLLLQVADKVASRGGTVLYVAGEESLEQIRLRADRLGVAADLQMTRDTRAEHIAALLEEHKPALCIVDSIQTVTVEGEGAPGGVAQVRDGTAMLTRAAKETGTATVLVGHVTKDGTVAGPKVMEHIVDTTVFLETVGAFRLLRSVKNRFGQAGELGVFEMRGEGLIAVDNPSAAFLAERPLDVPGSVVAATVDGQRPMLLEVQALASKTPYPNARRVVVGLDPRRVDVVLAVLERRLDLTLGGLDVYVNLAGGLKVPDPGLDLAVALAVYSAVVGRALPQNVAVFGEVGLAGEVRSTQMALRRAEEAGRAGYKRLVVPPGLDGQAGVKSVEEAVKAVWR
What is the function of this protein?
Plays a role in DNA damage repair (Ref. 2).  Following severe irradiation (IR, 7 kGy of gamma irradiation), genomic DNA is fragmented and progressively degraded for the first 1. 5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III.  This is followed by massive DNA synthesis and genome reassembly in the next hour.  Optimal priming of DNA synthesis requires both RecA and RadA.  Pol III initiates DNA synthesis while both Pol I and Pol III are required for its continuation (PubMed:19303848).
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: DGTP_ECO45
Sequence: MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLYPEDAESQPLTDDRCSVAALRLRDGEEPLNALRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLNLPLSDFTELVEKERVKRFPIETRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: RPIA_NEIMF
Sequence: MTTQDELKRIAAEKAVEFVPENEYIGIGTGSTINFFIEALGKSGKKIKGAVSTSKKSSELLAQYDIPVVSLNEVSGLAVYIDGADEVNHALQMIKGGGGAHLNEKIVASASEKFVCIADESKYVSRLGKFPLPVEVVESARSLVSRKLLAMGGQPELRIGYTTFYGNQIVDVHGLNIDKPLMMEDEINKITGVLENGIFARDAADVLILGTEEGAKVIYPCQG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RL3_MESH2
Sequence: MKGILGKKVGMSQLFTTEGIAISVSIIEVPENIVTKIITKEKNSYNAIQLAAFDKKQSRFLKPEIGHFAKANTKPKRFIKEFRDFQGYKLGQTVDVSIFSPGEFVDVTGTSKGKGFAGTIKRYNQAIGPRSHGGGGGSKPIRQTGSLGDISGNKVVKGMTMPGRLGHEKVTKQSLEIIKVDKENNLLVLKGSVPGPKKSFLVIKSAIKKPNPKNPVSLFVPNSDKEVKNE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: VPC32_MYCTU
Sequence: MILVDTSVWIEHLRAADARLVELLGDDEAGCHPLVIEELALGSIKQRDVVLDLLANLYQFPVVTHDEVLRLVGRRRLWGRGLGAVDANLLGSVALVGGARLWTRDKRLKAACAESGVALAEEVS
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Upon expression in M. smegmatis inhibits colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB32.
What are the official names of this protein?
Ribonuclease VapC32, RNase VapC32, Toxin VapC32.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: MPGP_SALTY
Sequence: MLSIHDPLLIFTDLDGTLLNSHTFEWQPAAPWLTRLHESGVPVILCSSKTAAEMLQLQTTLNLQGLPLIAENGAVIQLDVHWEDHPNYPRLIAGISHNEIRLVLHKLREKEQFKFTTFDDVDDQVISEWTGLNRAQSALTRLHEASVSLIWRDSDERMAQFVARLNDLGLQFVHGARFWHVLDASAGKDQAANWLIEAYRRQWRARPLTLGLGDGPNDAPLLDVMDYAVVVKGLNREGVHLRNDDPQRVYRSQNEGPDGWREGMDYFFSRS
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NP_ADECT
Sequence: MAILISPTNNTGWGLGTHKLFGGAKQKSDQHPVYVQAHYRASWGSKGRRRRQGRARGAPLDPKTEAEMVATIDEVARNGPPAARLVLEAARRVGAYNLRRARKLTPAGRAMMAMRARQMVKQAKKRKRRVRFRQ
What is the function of this protein?
Plays a role in the inhibition of host immune response within the nucleus.  Interacts with cellular nucleosomes and immobilizes the host immune danger signal HMGB1 on chromatin.  In turn, prevents HMGB1 release out of the cell and thus decreases inflammation.  Also plays a role in the wrapping and condensation of the viral DNA.  May also promote viral genome import into the nucleus.
What are the official names of this protein?
Pre-histone-like nucleoprotein, Pre-core protein VII, pVII.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae histone-like nucleoprotein family.
What are the subcellular locations of this protein?
[Histone-like nucleoprotein]: Virion. Note=Located inside the capsid in association with the viral DNA (core). Present in about 1070 copies per virion. SUBCELLULAR LOCATION: [Pre-histone-like nucleoprotein]: Host nucleus, host nucleolus.
Protein: RL6_HELHP
Sequence: MSRVGKKPINIPKGVEVSVQGSKILFKGAKEQKELETYGRVQIHLQDGTLSFACVDSQAQSRAYWGTYRALANNIIVGLSQGFTKVLEINGVGYKANISGKNLEMALGFSHPVIYPIPAGVEMSVDKNTITIKGADKQQIGQIAAEIRKFRPPEPYKGKGIKYSDEMIVRKAGKTSKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: NTPPB_ECO57
Sequence: MPKLILASTSPWRRALLEKLQISFECAAPEVDETPHSDESPRQLVLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTFYTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITLFERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMKL_STUS1
Sequence: MTDRHELILTCPKGLEGLLLEEATALGLEEGREQTSAVRGYGALEVGYRLCLWSRLANRVLLVISRFPTVDAETLYQGVHAVDWAEHLLPSGSLAVEFSGRGSGIDNTHFGALKVKDAIVDRLRSASGERPSIDKLDPDLRVHLRLDKGQAVLSLDLSGHSLHQRGYRLQQGAAPLKENLAAAILIRAGWPRIAAAGGALTDPMCGVGTFLVEGAMMAADIAPNLKRERWGFSAWLGHVPALWNRLHADAQARAEAGLARPPLWIRGYEADPRLIQPGRNNIERAGLSSWIRIYQGDVGSFEPRPDQNQKGLVICNPPYGERLGDEASLLYLYQNLGERLRQACLGWEAAVFTAAPDLGKRMGIRSHKQYAFWNGALPCKLLLIKVELDQFVTGQRAGSTEPQPQQAPVEQARLSEGGQMFANRLQKNLRQLGKWARREGIECYRLYDADMPEYALAVDLYRDWVHVQEYAPPRSIDPDKAQARLLDALAAIPQALGIAREKVVVKRRERQSGTRQYERQASQGEFLEVSEGGVKLLVNLTDYLDTGLFLDHRPLRLRIQREAAGKRFLNLFCYTATATVHAAKGGARSTTSVDLSRTYLDWARRNLSLNGFSDRQRLEQGDVMAWLEADRGEYDLIFIDPPTFSNSKRMEGVFDVQRDHVALLDLAMARLATGGTLYFSNNFRKFVLDASLMDRYAVEEITASTLDEDFRRNPRIHRAWKLQAR
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
Protein: GLSA_SHESR
Sequence: MPEQALLEEVVDKVRPLLGQGKVANYIPALANVDAGKLGIAVTTIDGETIGAGDYLEPFSIQSISKVFSLTLALTLYEETEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRALSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTLDGTELISQVQTRQLNALLATSGLYDGAGEFAYRVGMPGKSGVGGGIIAVIPGELSVCVWSPELDNQGNSLAGTAMLEHLSQRLGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: PSBF_COECR
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SUMF1_HUMAN
Sequence: MAAPALGLVCGRCPELGLVLLLLLLSLLCGAAGSQEAGTGAGAGSLAGSCGCGTPQRPGAHGSSAAAHRYSREANAPGPVPGERQLAHSKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLSEQVKTNIQQAVAAAPWWLPVKGANWRHPEGPDSTILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMCHRSYCYRYRCAARSQNTPDSSASNLGFRCAADRLPTMD
What is the function of this protein?
Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent (PubMed:12757706, PubMed:15657036, PubMed:15907468, PubMed:25931126, PubMed:16368756, PubMed:21224894).  3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile (PubMed:12757706, PubMed:15657036, PubMed:15907468, PubMed:25931126, PubMed:16368756).  Known substrates include GALNS, ARSA, STS and ARSE (PubMed:12757706, PubMed:15907468, PubMed:15657036).
What are the official names of this protein?
Formylglycine-generating enzyme, FGE, C-alpha-formylglycine-generating enzyme 1, Sulfatase-modifying factor 1.
What is the protein family that this protein belongs to?
Belongs to the sulfatase-modifying factor family.