PharMolix/UniProtQA huggingface dataset:
Protein: SCD3_MOUSE
Sequence: MPGHLLQEEMTPSYTTTTTITAPPSGSLQNGREKVKTVPLYLEEDIRPEMKEDIYDPTYQDEEGPPPKLEYVWRNIILMALLHVGALYGITLVPSCKLYTCLFAFVYYVISIEGIGAGVHRLWSHRTYKARLPLRIFLIIANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGGKLDMSDLKAEKLVMFQRRYYKPGILLMCFILPTLVPWYCWGETFLNSFYVATLLRYAVVLNATWLVNSAAHLYGYRPYDKNIDPRQNALVSLGSMGEGFHNYHHAFPYDYSASEYRWHINFTTFFIDCMAALGLAYDRKRVSKATVLARIKRTGDGSHKSG
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA (PubMed:16443825, PubMed:26098370).  Has a strong preference for saturated fatty acids with chain lengths of 14 or 16 carbon atoms (C14:0 and C16:0), and has only very low activity with stearatate (C18:0) (PubMed:16443825, PubMed:26098370).  Required for the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).
What are the official names of this protein?
Acyl-CoA desaturase 3, Delta(9)-desaturase 3, Delta-9 desaturase 3, Fatty acid desaturase 3, Palmitoyl-CoA desaturase, Stearoyl-CoA desaturase 3.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane.
Protein: MNMG_SHEB2
Sequence: MHFHERFDVIVVGGGHAGTEAALAAARMGSKTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEIDALGGAMAIATDYAGIQFRTLNSSKGPAVRATRAQADRALYRQKIQNILQNQPNLRIFQQAVDDLIVENHQVVGVVTQMGLAFESPAVVLTTGTFLSGKIHIGLENYSGGRAGDPPAIALANRLRELPIRVGRLKTGTPPRIDANTIDFSQMAEQKGDSPLPVMSFMGDVSHHPKQISCWITHTNEKTHEIIRGGLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKSSHQIFIEPEGLNTNEIYPNGISTSLPFDVQLNLVRSIKGMENAEIMRPGYAIEYDYFDPRDLKNSLETKAINGLFFAGQINGTTGYEEAGAQGLLAGMNASLQVQGKEAWCPRRDEAYLGVLVDDLSTLGTKEPYRMFTSRAEYRLLLREDNADIRLTAKGRELGLVDDARWAAFSEKLESIELELQRLRGQWVHPNSPLIHALNPHLNTPISREASFEELLRRPEMDYSKLMQIEGFGPGLEDPQAAEQVQIQVKYSGYIQRQQEEINKAVRNENTGLPLTLDYKEVPGLSNEVIAKLNNHKPETIGQASRISGITPAAISILLVHLKKRGLLRKSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHANK_CAEEL
Sequence: MNQEEDTVNLQIFVPELNVRKFLAVTQNDFIWDVKRKLLATLPQALPQAFNYGLFLPPCDGRAGKFLLEDRTIRDYPFTDCVPYLELKYKKRVYKMLNLDEKQLKAMHTKGQLKKFMDYVQQKNNEKVEKMCSQGLDANFHDAQGETPLTLAAGIPNNRAVIVSLIGGGAHVDFRNSEGQTAMHKAAFLSSFENVKTLIELGASPNYRDPIGLTPLYYNMLTADSNDQVAEILLREAADIGVTDMHGNHEIHQACKNGLTKHVEHLLYFGGQIDAENVNGNSPLHVCAVNNRPECARVLLFRGADHLAVNKQGQTALHVSHIVGNPGVADVVQAHNPKSSVPYRGTPQYSTRRRLSSTITRRRSMSQSSICSQDVYRTPQSVRKGPMSAAPSPSPSRSSRTTITPSEYGTMRRSGMDSMRGGGMIAAGHETNIARILVIPRGVKGFGFILRGAKHVAMPLNFEPTAQVPALQFFEGVDMSGMAVRAGLRPGDYLLEIDGIDVRRCSHDEVVEFIQQAGDTITLKVITVDVADMSRGGTIVHRPPTASSRHSLVFTPTPSAIYSSTKASSVYRMRFDTHDAHGVDYYAPNEIRNAYSESRHASVRQRPGSGRRISAAELENLMVRQRVPSVQGSPYQMQYDQESLNGGYSSKKYNSVSDMKRRKGQRNVVASSAGLNRSTFEQAAPTTSTFEYNCSSRSTPQLSRMDSFDSFDDEDEMPAPPPASYISPDLQRDSSMQRSEYSRPFRPTSRPKTPPPPPPMQHQNHQNHQYQQQHPSLPRSASTPQPIQQQQSSIPPPPPPPPPPHCEPTMVHVEFTPPSTSSVPPPPPPLPPISSGAPPPPPPPPPGGLMHVAASAPVLMSNSKGISADALKSVQLKKAEPRETSAASVSNNNNNNNNSTTDFQMDLKNALAKRRSKVAHDVDEDEERESRFEGLSLRETVRENVVERGKGIQNIGIVNKKDSGYTSSRTSLEPSESEEKDHRPHFSLDHSPNVQRVTLISQHLEDNYGQKDNMSVASSSTASSSSTVDLTKPGCFVVPSHVIPPVDYDDDPDSGTGDSDGEIRCSEISFEHKKVDVWSVDDVIGWLSSLHLSEYTPAFRSQRINGRCLRQCDRSRFTQLGVTRIAHRQIIESALRGLLQ
What is the function of this protein?
Scaffold protein that most likely acts in the postsynaptic density (PSD) of excitatory synapses which orchestrates synapse formation and maintenance at neuromuscular junctions (PubMed:28477407).  Associates with and trafficks the L-type calcium channel egl-19 to the cell surface of body wall muscles to ensure the function of the calcium channel and therefore maintain the Ca(2+) current density (PubMed:28477407).  The maintenance of Ca(2+) also allows for the downstream regulation of Ca(2+)-induced expression of genes such as gem-4 (PubMed:28477407).  Plays a role in the regulation of the defecation cycle, and this may be in association with the inositol trisphosphate (IP3) receptor itr-1, which in turn mediates periodic calcium release and muscle contractions (PubMed:15013747, PubMed:21191812).  Required for normal fertility and pharyngeal pumping (PubMed:21191812).
What are the official names of this protein?
Protein shank.
What is the protein family that this protein belongs to?
Belongs to the SHANK family.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Cytoplasmic vesicle. Postsynaptic density. Note=Localizes to sperm pseudopodium.
Protein: FET3_KLULA
Sequence: MKVSTHHFLPSLLVALWSWATVAQAATHTFNWTTGWGNYNVDGNFERPVITCNGEFPWPDLKVKRGDRIQVYLTNGFDDRNTSLHFHGLSQNGTNMMDGPEMITQCPIAPGDTMLYNFTIDDNDGTYWYHSHTGGQYQDGMKGTLVVEPEDSLPFDYDEEVVVQLAEWYYDNVDTLDRKFMNVYNPTGAEPIPQNLIINNTRNMTWNVEPDTTYLLRIVNTGGFVSQYFWIEDHDMTVVEVDGVYVEKNTTSMLYITVAQRYSVLIHTKNDTSKNYAIMQKFDDTMLDVIPNDLMLNATSYMMYDKDGEKPEQSYVDSIDDFLDDFYLTPLDKVELYEDPDYTITVDVVMDNLKNGVNYAFFNNLTFTAPKVPTLMTALSAGKDALNPLVYGTNTNAFVLKKDEIIEIVLNNNDTGKHPFHLHGHIFQLVDRERGYDDAIGEGPHPFDPEDHNPFPDYPMMRDTVYVNPQSSIVLRFKADNPGVWFFHCHIEWHLKQGLALLLIEAPEEMQNTESQQLTDNHKQVCENVGLSWEGNAAGNTNDFLDLVGQNVQVANIPDGFTAKGIVAMTFSCLAGVLGLISLSTYGLMGVKKSEEEIIRDLGMDPDAVEKVDVSDINSDEDSSRTSKNIE
What is the function of this protein?
Iron transport multicopper ferroxidase required for Fe(2+) high affinity uptake.  Required to oxidize Fe(2+) and release it from the transporter.  Essential component of copper-dependent iron transport (By similarity).
What are the official names of this protein?
Iron transport multicopper oxidase FET3.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein; Extracellular side.
Protein: RSGA_BORRA
Sequence: MNSSTFEVLWGVNNIYSVVEVNTNTVYEGVIKGKFLNTREKEYSPLVPGDFVCGDIYDEHKVYIKERMERRNVFWRYNKKVALRQVIVSNIDNILIVSSATLPEFKNSFIDRTLIVAEEQGITPIILVNKVDEGINLRVDSFIKIYEYLGYRVIKTSVVTLQGIDEVKKIIKNSRTSFIGQSGVGKSSLINVIDLNASQAINEISYKYARGRHTTVYAVAFHSDNKILIDTPGIKEFGIEGLGYLELKYYFKEFKYFNDLCRFNSCLHINEPNCFVISQIGFKIAEARYNSYLKIFSELKRYKSYAREIFGKN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIM3_HUMAN
Sequence: MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
What is the function of this protein?
E3 ubiquitin ligase that plays essential roles in neuronal functions such as regulation of neuronal plasticity, learning, and memory (By similarity).  In addition to its neuronal functions, participates in other biological processes such as innate immunity or cell cycle regulation.  Component of the cytoskeleton-associated recycling or transport complex in neurons, polyubiquitinates gamma-actin, thus regulating neuronal plasticity, learning, and memory (By similarity).  Ubiquitinates postsynaptic scaffold GKAP, a neuronal substrate involved in synaptic remodeling and thereby modulates dendritic spine morphology (By similarity).  Positively regulates motility of microtubule-dependent motor protein KIF21B (By similarity).  Induces growth arrest via its RING-dependent E3 ligase activity and ubiquinates CDKN1A (PubMed:24393003).  Positively regulates TLR3-mediated signaling by mediating 'Lys-63'-linked polyubiquitination of TLR3 (PubMed:32878999).  In turn, promotes the recognition and sorting of polyubiquitinated TLR3 by the ESCRT complexes (PubMed:32878999).
What are the official names of this protein?
Tripartite motif-containing protein 3, Brain-expressed RING finger protein, RING finger protein 22, RING finger protein 97.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome. Golgi apparatus, trans-Golgi network. Cell projection, dendrite.
Protein: YS001_HUMAN
Sequence: MEPWWPRGTGANAPWVLVAVPPGLFPSLLGACCTLTSSSWLQPRFWGLGWRVEVGLEGAGGSSQNYQAALPSFFCLAASPASRPAIFGILAAEPPSASPQAPWPKPGCASPHGSHWPSILIC
What are the official names of this protein?
Putative uncharacterized protein UNQ6493/PRO21345.
Protein: VXIS_BP434
Sequence: MYLTLQEWNARQRRPRSLETVRRWVRECRIFPPPVKDGREYLFHESAVKVDLNRPVTGSLLKRIRNGKKAKS
What is the function of this protein?
Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination at the att site.
What are the official names of this protein?
Excisionase.
Protein: RL30_MYCBO
Sequence: MSQLKITQVRSTIGARWKQRESLRTLGLRRIRHSVIREDNAATRGLIAVVRHLVEVEPAQTGGKT
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PETL_CRUWA
Sequence: MPTITSYFGFLLAALTITSVLFIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PTPS_RAT
Sequence: MNAAVGLRRRARLSRLVSFSASHRLHSPSLSAEENLKVFGKCNNPNGHGHNYKVVVTIHGEIDPVTGMVMNLTDLKEYMEEAIMKPLDHKNLDLDVPYFADVVSTTENVAVYIWENLQRLLPVGALYKVKVYETDNNIVVYKGE
What is the function of this protein?
Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases.  Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
What are the official names of this protein?
6-pyruvoyl tetrahydrobiopterin synthase, PTP synthase, PTPS.
What is the protein family that this protein belongs to?
Belongs to the PTPS family.
Protein: LUXS_VIBC1
Sequence: MPLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIPELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLRELRID
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: UVRC_CLONN
Sequence: MFDFEYQLKIIPEKPGVYLMKNSLGEVIYVGKAKVLKNRVRQYFQNSKNHGSKVRAMVKNIAEFEYIITDSEMEALILECNLIKKYRPRYNILLKDDKHYPFLKITTNEDFPRIFVTRVRAKDGARYLGPYPETSAVYETIELIKKIFPLRTCRLNIKENGEPVKPCLNYHIKLCTAPCAGYISREEYGKTIKKIIDLLNGKDNEVINDLKIKMEKASSELKFEEAASFRDKLLAVEKIRERQKIISSNFENEDFINMYSEEIDLCAQIFFVRDGKIMGREHFILDRSIFGNNADIISNFIKDFYGGTAFIPKTIYVPEVMDIELLENWLSSKKGSKVSIKIPQKGEKKKILDLVESNAKNTLEQFKLKLKVDKELYSNTLKELQNILELEEIPNRIEAYDISNIQGVDSVGSMIVFDKGKPKNSDYRRFKIKTVKGANDYDSMREILTRRFTHGLEEIKEIQKRNLLLSGAKFSVFPDLILMDGGKGQVNIALEVLEKLNINIPVCGMVKDDKHKTRGLVYNNKEINIKSNNKIMQFITRVQDEVHRFAITYHRSLRNRRVLHSVLEDIPNIGEKRRKELLQKFGSVENIKKASYDELLDTNSINQKAAKSIIDYFNNAK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_PSYWF
Sequence: MPRSLKKGPFIDAHLFAKVEKAVESNSRKPIKTWSRRSMILPQMVGLTISVHNGRTHVPVIISEQMVGHKLGEFAPTRTYRGHGFDKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CKP1_CONPI
Sequence: GEDEYAEGIREYQLIHGKI
What is the function of this protein?
Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors.  This toxin has highest potency for the NR2B/GRIN2B subunit.  It induces sleep in 10-day-old mice when injected intracranially, and hyperactivity in 24-day-old mice.
What are the official names of this protein?
Conantokin-Pr1, Con-Pr1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin B superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HNRPF_RAT
Sequence: MMLGPEGGEGYVVKLRGLPWSCSIEDVQNFLSDCTIHDGVAGVHFIYTREGRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLDRMRSGAYSAGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDSEFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGLESQSVSGCYGAGYSGQNSMGGYD
What is the function of this protein?
Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm.  Plays a role in the regulation of alternative splicing events.  Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein F, hnRNP F.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: DDL_YERPN
Sequence: MAEKVAVLLGGTSAEREVSLLSGQAVLAGLKEAGIDAYGVDTKDFPVTQLKEQGFDKVFIALHGRGGEDGTLQGVLEFLQLPYTGSGVMASALTMDKLRTKLVWQALGLPISPYVALNRQQFETLSPEELVACVAKLGLPLIVKPSHEGSSVGMSKVDHASELQKALVEAFQHDSDVLIEKWLSGPEFTVAILGDEVLPSIRIQPPGVFYDYDAKYLSDKTQYFCPSGLSDESEQQLAALALQAYHALDCSGWGRVDVMQDRDGHFYLLEVNTSPGMTSHSLVPMAARQYGLSFSQLVARILMLAD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPR_STRCO
Sequence: MDGRRRNPYELTEDTPVYVISVAAQLSGLHPQTLRQYDRLGLVSPDRTAGRGRRYSARDIELLRQVQQLSQDEGINLAGIKRIIELENQVAELQARAAELAAALDGAATAMRQREAAVHASYRRDLVPYQEVQQTSALVVWRPSRRGQSSD
What is the function of this protein?
Binds to three inverted repeats (IR1-IR3) in the promoter region of the dnaK operon.
What are the official names of this protein?
Putative heat shock protein HspR.
Protein: LSPA_DEIRA
Sequence: MWPFSRQQNVSRILPIVPTAPRRFPVWFPAVLVLVLIALDQWLKAWALAHLQLNAPAIPVIPGVLDWELTFNTGAAWSMFSGSAVPLALGRILVGLGILSYLLWKPQGRFLTVVLSMIAAGAIGNSIDGLQRGQVTDMIHSPLLSAVTEAINGTRFPIFNIADMCVVGGTILLLVASLLPERKREKAVPEA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPMA_CHLTE
Sequence: MKKLVLLRHGESQWNRENRFTGWVDVDLSEKGREEARTAGQLLKDEGFVFDLAYTSVLKRAIRTLWTVLDEMNLMWIPVTKNWRLNERHYGALQGLNKAETAQRHGDEQVLIWRRSYDTPPPALTESDEFWPGKDPRYASLSSQELPATECLKDTVARFLPYWHETIAPQIRDGKNVIITAHGNSLRALVKYLDNISDEDIVGLNIPTGIPLVYELDDDLKPLKSYYLGDQEELKKKVEVVVKQGKA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RSMJ_PECAS
Sequence: MSICLIAEEGADSGALSSLAERWGLVSDPNAVMALVLTTERLELRKQDEPKLGAIFVDFVAGPMAHRRRFGGGRGEAVAKAVGIKKDYLPDVVDATAGLGRDAFVLAALGCHVRMVERNPVVAALLDDGLKRGYQDAEIGPWLRERLTLLHASSMTALRDITPPPDVVYLDPMFPHKQKSALVKKEMRVFQSLVGADDDADALLEPARALAKKRVVVKRPDYAPPLAGVPAQSMLETKSHRFDFYLPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGT_ECO5E
Sequence: MQIKRLIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LGT_ECO45
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANB_AGRVS
Sequence: MSAPPRQKRLTPTTIAALKHQRPIVSLTAYTTPMARLMDAHCDLLLVGDSLGMVLYGLDTTVGVTLEMMIAHGQAVLRGVNRACVIIDMPFGSYQESREQAFRNAARIMKETGCDGIKLEGGTEMAETVAFLVERGIPVLGHVGLMPQQVNTSGGYRSKGHDEAEADKIRADATAIAKAGAFALVIEGTVEPLAREITQTLSVPTIGIGASPACDGQILVSDDMLGLFNDFKPRFVKHYAELAGVISKAVEDYATEVKARQFPGPEHTFQPRKS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YH1E_YEAST
Sequence: MYKITTIYLWLKSYLSFFIGLDNLDFLTLIRFFQCRLQNKLGLQDILDFFCNLCGHSMVRTCNMVEAAQKQNRITFGSIYVKLHPLVKLCTGIVWAPRV
What are the official names of this protein?
Putative uncharacterized protein YHR214C-E.
Protein: RS17_SHIF8
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ASTA_SALTI
Sequence: MRVIRPVEHADIAALMQLAGKTGGGLTSLLANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARVVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPALGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: COX16_HUMAN
Sequence: MFAPAVMRAFRKNKTLGYGVPMLLLIVGGSFGLREFSQIRYDAVKSKMDPELEKKLKENKISLESEYEKIKDSKFDDWKNIRGPRPWEDPDLLQGRNPESLKTKTT
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:29355485, PubMed:29381136, PubMed:33169484).  Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2) (PubMed:29355485, PubMed:29381136).  Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6 (PubMed:29381136).  Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines (PubMed:29381136).
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial, hCOX16.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.