PharMolix/UniProtQA huggingface dataset:
Protein: WDR62_MOUSE
Sequence: MAALAAGGYTRSDTIEKLSSVMAGVPARRNQSSPPPAPPLCLRRRTRLAAAPEDTVQNRVTLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVVLNPKENKQQHIFNTTRKSLSALAFSPDGKYIVTGENGHRPTVRIWDVEEKTQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEASTEAKVTSTVPLVGRSGILGELHNNIFCGVACGRGRMAGNTFCVSYSGLLCQFNEKRVLDKWINLKVSLSSCLCVSDELIFCGCTDGIVRIFQAHSLLYLTNLPKPHYLGVDVAHGLDSSFLFHRKAEAVYPDTVALTFDPVHQWLSCVYKDHSIYIWDVKDIDEVSKIWSELFHSSFVWNVEVYPEFEDQRACLPSGTFLTCSSDNTIRFWNLDSASDTRWQKNIFSDSLLKVVYVENDIQHLQDLSHFPDRGSENGTPMDMKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELIKVEAHDAEVLCLEYSKPETGVTLLASASRDRLIHVLNVEKNYNLEQTLDDHSSSITAIKFAGTRDVQMISCGADKSIYFRSAQQASDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVSGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISLIDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWHLGPEITTCMKQHLLEINHQEQQQQPKDQKWSGPPSQETYASTPSEIRSLSPGEQTEDEMEEECEPEELLKTPSKDSLDPDPRCLLTNGKLPLWAKRLLGDDDVADSSAFHAKRSYQPHGRWAERAEQEPLKTILDAWSLDSYFTPMKPENLQDSVLDSVEPQNLAGLLSECSLGNGHTSPGEGLVSYLLHPELGSPKEDNRGHPSYLPLQREATEASELILCSPEAEVSLTGMHREYYEEETEAGPEDQQGDTYLRVSSVSSKDQSPPEDSGESEAELECSFAAAHSSAPQTDPGPHLTMTAGKPEYPSTEELSQPELPGLGNGSLPQTPEQEKFLRHHFETLTDAPTEELFHGSLGDIKISETEDYFFNPRLSISTQFLSRLQKTSRCPPRLPLHLMKSPEAQPVGQGGNQPKAGPLRAGTGYMSSDGTNVLSGQKAEETQEALSLLDRKPPTPTSVLTTGREQSISAPSSCSYLESTTSSHAKTTRSISLGDSEGPVTAELPQSLHKPLSPGQELQAIPTTVALTSSIKDHEPAPLSWGNHEARASLKLTLSSVCEQLLSPPPQEPPITHVWSQEPVDVPPSMAVTVASFCAPSPVDMSTLGLHSSMFLPKTSASGPLTPPAHLQLLETRSRVPGSTAALLEPTPDASGVIADSPGHWDTEVPTPELLGSVESVLHRLQTAFQEALDLYRMLVSSSQLGPEQQQAQTELASTFHWILNQLEASNCMAAANLAPPQTLPSPDPLSLPTLCPLASPNLQALLEHYSELLVQAVRRKARGD
What is the function of this protein?
Required for cerebral cortical development.  Plays a role in neuronal proliferation and migration (By similarity).  Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity).
What are the official names of this protein?
WD repeat-containing protein 62.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Shows cell cycle-dependent localization. Accumulates to the spindle pole during mitosis (By similarity). Colocalizes with CDK5RAP2, CEP152 and WDR62 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (By similarity).
Protein: NCBP2_ANOGA
Sequence: MSSQIQSVHTPSVSLSKYRDQHFKGSRHEQEKLLRVSSTLYVGNLSFYTTEEQIHELFSRCGDVRRIIMGLDKFKKTPCGFCFVEYYSRLDAESAMRYINGTRLDDRIVRVDWDAGFIEGRQYGRGKTGGQVRDEYRQDHDLGRGGYGKMVQMGQLGAPSMRE
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing.  Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires Cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRS38_MOUSE
Sequence: MAALTSGLGVLGYLLFPLLLASPTWVTSVSRRHPKSQANSLSGDVACGQPVLQGKLLGGEFARDRKWPWQVSLHYSGFHICGGSILSAYWVLSAAHCFDRGKKLETYDIYVGITNLEKANRHTQWFEIYQVIIHPTFQMYHPIGGDVALVQLKSAIVFSDFVLPICLPPSDLYLINLSCWTTGWGMISPQGETGNELLEAQLPLIPRFQCQLLYGLSSYLLPEMLCAADIKTMKNVCEGDSGSPLVCKQNQTWLQIGIVSWGRGCAQPLYPGVFANVSYFLSWIRYHLQIIPNPPQILPSLSSSPKNTLIIFVTIMGHLLVL
What are the official names of this protein?
Serine protease 38, Marapsin-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_FERNB
Sequence: MGLKRFKPTTPGRRFMIIPDFSEITKTKPEKSLVVPLKKSAGRNHHGRVTVRFRGGGHKRLYRIVDFRRWEKENIPAKVASIEYDPNRTARIALLIYADGEKRYILAPNGLNVGDTVMSGPEAEIKPGNALPLENIPVGTIVHSIEFLPRGGAKIARSAGVACQLMAKEGNYALLKMPSGELRKVHIKCYATVGVVGNEDHKNEVSGKAGRERWKGRKPHVRGVVMNPVDHPHGGGEGRGKGHHPQSPWGVPAKGYKTRRGKRASDKFIVRRRNG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: YBHG_ECOHS
Sequence: MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTVNLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRAVEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PPTA_ASPFU
Sequence: MGSAQNERIPSLTRWYIDTRQLTVTNPSLPLLEALQPSDQEAVKRFYHLRDRHMSLASNLLKYLFIHRSCCIPWNKISISRTPDPHRRPCFIPSPALTEATDEPIPGIEFNVSHQASLVALAGTIIPQSHGASPNPTTVFANPSPSSVPAPSVPQVGIDITCVDERHARTSSAPSTRDQLAGYVDIFAEVFSSRELDTIKNLGGRFPADAQDGEAVEYGLRLFYTYWALKEAYIKMTGEALLAPWLRELEFTDVIAPEPAPAPGQGSAENWGEPYTGVKIWLYGKRVEDVRIEVVAFETGYIFATAARGAGLGAESRPLSRDAGVAVSVDRWMHMEKIDIDRDIAPCATGVCQCTKKQP
What is the function of this protein?
Acyl-carrier-protein synthase that transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of an acyl-carrier-protein (PubMed:12664133, PubMed:21195204, PubMed:28720735).  The 4'-phosphopantetheine (4'-PPT) portion of CoA provides the essential prosthetic group for a number of carrier proteins and multi-domain enzymes, priming them for the acceptance of acyl building blocks in fatty acid synthesis and many aspects of secondary metabolism mediated by polyketide synthases (PKSs) and non-ribosomal peptide synthetases (NRPSs) (PubMed:21195204, PubMed:28720735).  PptA is able to transfer the cofactor to a broad range of enzymes with acyl- or peptidyl-carrier protein domains and activates target enzymes involved in the synthesis of lysine, but also secondary metabolites including gliotoxin, fumigaclavine C, fumiquinazole A, fumiquinazoline C, pyripyroprene A, fumagillin, the siderophores triacetylfusarinine C (TAFC) and ferricrocin (FC), and dihydroxy naphthalene (DHN)-melanin (PubMed:21195204, PubMed:28720735).  Plays an essential role in virulence (PubMed:28720735).
What are the official names of this protein?
4'-phosphopantetheinyl transferase A, PPTase A, Acyl-carrier-protein synthase pptA, Phosphopantetheine:protein transferase pptA.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily.
Protein: SYN_SALCH
Sequence: MSVVPVADVLQGRVAVDQEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEEVLHLTTGCSVVVTGKVVASPGQGQSFEIQATKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFDEQGFFWVSTPLITASDTEGAGEMFRVSTLDLENLPRNDQGRVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFADLEDNARLAEAMLKYVFNAVLEERADDMKFFAERVDKDAIARLERFVSTDFAQVDYTEAVAILERCGKTFENPVFWGVDLSSEHERYLAEEHFKAPVVVKNYPKEIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIP_PLETG
Sequence: ARTQPGNIAPVGDFTLYPNAPRQGHIVA
What is the function of this protein?
Inhibits protein synthesis in animal cells.  Does not possess ribonuclease activity.
What are the official names of this protein?
Ribosome-inactivating protein pleuturegin, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family.
Protein: DEOC_ACTPJ
Sequence: MSLKDSAKIALSLMDLTTLNDNDTDEKVIALCQQGKTEFGTPAAVCVYPRFVPIARKALKAQGTEQVKIATVTNFPHGNDDIDIAVAETKAAVAYGADEVDVVFPYKALMAGNEQIGFELVQQCKAVCQASNVLLKVIIETGELKTAELIRKASEISIKAGADFIKTSTGKVPVNATLESARIMLETIRDLKVADRVGFKAAGGVKTAEEAAQYLALAQEILGHDWVNSDHFRFGASSLLTNLLAALNGQANQKVSGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR10_YEAST
Sequence: MTGPGPEINKEEHPSSPGKKQITYNSIPKNANLIDGSTNSSKRPIEKYDKRIADPTKSYFPHSISRTPRRKYTYILVLTSLNGTFESKHVVIPFKPDGLKLGRPVANSNSSSSSSLRGGKRVDSHTFSQVRSDNGNFDSRVLSRNHALLSCDPLTGKVYIRDLKSSNGTFINGQRIGSNDVEIKVGDVIDLGTDIDTKIEHRKISATVEELFVQPLLESPIFENEDSDDCHTITEKEEAAAITSHIYGDSNNLELEEVILGSDTEILSGIFINNCIGTSPTLSNIIKTLAMEIPFSKCDNFKLQSMENFLINYTTHLEYTNKLLVEKNDQQLVKLQNGLRRKLSGKYEKIIEQNRNQVKQLERDHMFFKKSFEVKKRRNNEKQKSMEREIEDLKTRLEVERYKNSQMMKKNKQKEQELSTASKKKTTEHDTRGVPGMNPKGTDKFSIKNTLCNHFTLLTFGTISIGIIAIVFKILSPN
What is the function of this protein?
Participates in the control of the reentry into the cell cycle following pheromone treatment.
What are the official names of this protein?
Factor arrest protein 10.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: HSLV_STAAT
Sequence: MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYESLKVAADICVFTNDNIVVETL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH3_DICDI
Sequence: MISNFLKSNNIKNNSPFRSFCTRYSESHEWIKFNHRNKTCTLGITKYASDQLKSIVNINLPDLNSTITRKQPFGNIESTKTVADLFSDVDGKAVLLNSDVIVDPTIVSHSPEDKGWLIKMESNDFESFNKMMTKSEYGQFLKDINKSNV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity).
What are the official names of this protein?
Putative glycine cleavage system H protein 3.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: Y1478_MYXXD
Sequence: MPSFDVVSKIDLAELDNAVNQTKKELSTRYDFQGTHADVVLAPDNTAITVKANSEDRVQAAKEVLLTKLAKRNISLFALEYGDIEKTGLHNVKQVIKLQQGIPVEKSKELVKLLKDSKMKVQGSIQADQLRVTGKNRDDLQAAIALFRKEQDRLKLDMQFINFRD
What are the official names of this protein?
UPF0234 protein MXAN_1478.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: QUEF_SALEP
Sequence: MSSYENHQALDGLTLGKSTDYRDNYDASLLQGVPRSLNRDPLGLTADNLPFHGADIWTLYELSWLNSQGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQTRFDTWETVRQTLERDLRACAQGNVSVRLHRLDELEGQPVAHFHGTCIDDQDISIDNYQFTTDYLQHAVSGEKQVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRKIDREKLLRYLVSFRHHNEFHEQCVERIFNDILRFCQPETLSVYARYTRRGGLDINPWRSNTDFVPATGRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_STAAR
Sequence: MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKDHPLQPHTDAVEV
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: SIAL_HUMAN
Sequence: MKTALILLSILGMACAFSMKNLHRRVKIEDSEENGVFKYRPRYYLYKHAYFYPHLKRFPVQGSSDSSEENGDDSSEEEEEEEETSNEGENNEESNEDEDSEAENTTLSATTLGYGEDATPGTGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEEEGNENEESEAEVDENEQGINGTSTNSTEAENGNGSSGGDNGEEGEEESVTGANAEDTTETGRQGKGTSKTTTSPNGGFEPTTPPQVYRTTSPPFGKTTTVEYEGEYEYTGANEYDNGYEIYESENGEPRGDNYRAYEDEYSYFKGQGYDGYDGQNYYHHQ
What is the function of this protein?
Binds tightly to hydroxyapatite.  Appears to form an integral part of the mineralized matrix.  Probably important to cell-matrix interaction.  Promotes Arg-Gly-Asp-dependent cell attachment.
What are the official names of this protein?
Bone sialoprotein 2, Bone sialoprotein II, BSP II, Cell-binding sialoprotein, Integrin-binding sialoprotein.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGB_AERHY
Sequence: MAISFDKAFGIHQYALSVRSKRAEVLSSNIANADTPGFKARDINFSQALEEAQHQQGFGLATTSEKHFALQSDAPGLTQYRNPLQPDTGDGNTVDVQQERSEFLRNSLEYQTSLEFMNSKISGLLKALKGEQ
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: RL20_NEIMB
Sequence: MPRVKRGVTARARHQKIFALAKGYRGRRKNVYRVAKQAVMKAGQYAYRDRRQRKRQFRQLWIVRINAGTRENGLSYSKFMNGLKRASIEIDRKVLADLAVFDKAAFAQLVEKAKAALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: DXS_PHOLL
Sequence: MSIDIAKYPTLALAENPEELRMLPKESLPKLCDELRQFLLNSVSRSSGHFASGLGTVELTVALHYVYKTPFDKLVWDVGHQAYPHKILTGRRDRIDTIRQKNGLHPFPWRDESEYDTLCVGHSSTSISAGLGMAIAAQREGKGRRTVCVIGDGAITAGMAFEAMNHAGDIDPDILVILNDNEMSISENVGALNNHLAQLLSGKLYTTLREGGKKVFSNLPPIKELLKKTEEHIKGMVVPGTLFEELGFNYIGPIDGHDVLTLTQTLKNMRELKGPQLLHIMTKKGRGYAPAEKDPISWHAVPKFDPTTGALPKSSDNRPTFSKIFGDWLCEEAANDKKLMAITPAMREGSGMVRFSREYPDQYFDVAIAEQHAVTFAAGLAIGGYRPIVAIYSTFLQRAYDQVIHDIAIQNLPVLFAIDRGGIVGADGQTHQGAFDLSFLRCIPNMVIMAPSDENECRQMLHTGYHYQQGPVAVRYPRGTGTGAEPQPFEQLPIGKGVIRRQGNKVAILNFGTLLPDAITAAESLDATVVDMRFVKPLDKELILDMADNHDLLVTLEENAIMGGAGSGVNELLMQKGRLVQILNIGLPDQFVPQGSQEEIKADLGLDAAGIQNSINKRLFS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RK36_PELHO
Sequence: MKIRASVRKICTKCQLIRRKGRIRVICSNPRHKQRQR
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MUKB_SALTI
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLSLAELKDKLDEMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRLTLEAIRVTQSDRDLFKHLISEATDYVAADYMRHANERRVHLDQALAFRRELYTSRKQLAAEQYKHVDMARELGEHNGAEGSLEADYQAASDHLNLVQTALRQQEKIERYEADLEELQIRFEEQNEVVAEAAEMQDENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAISALARAKELCHLPDLTPESAAEWLDTFQAKEQEATEKLLSLEQKMSVAQTAHSQFEQAYQLVAAINGPLARSEAWDVARELLRDGVNQRHLAEQVQPLRMRLSELEQRLREQQEAERLLAEFCKRQGKNFDIDELEALHQELEARIASLSESVSSASEQRMALRQEQEQLQSRIQHLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQEVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGAEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQIAEQLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPSLPIFGRAARENRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLSVAFEDDPEAEIRRLNGRRVELERALATHESDNQQQRLQFEQAKEGVSALNRLLPRLNLLADETLADRVDEIQERLDEAQEAARFVQQYGNQLAKLEPMVSVLQSDPEQFEQLKEDYAWSQQMQRDARQQAFALAEVVERRAHFSYSDSAEMLSGNSDLNEKLRQRLEQAEAERTRAREALRSHAAQLSQYSQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARQRRDELHAQLSNNRSRRNQLEKALTFCEAEMENLTRKLRKLERDYHEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQSVSFGQVNSVRLNVNVRETHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDEARRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTQAEDTPSEAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: TRIB2_BOVIN
Sequence: MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTNGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDFSVSNSGYGAKEVSDQLVPDVNMEETLDPFFN
What is the function of this protein?
Interacts with MAPK kinases and regulates activation of MAP kinases.  Does not display kinase activity (By similarity).
What are the official names of this protein?
Tribbles homolog 2, TRB-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=May associate with the cytoskeleton.
Protein: SYT_CLOK5
Sequence: MIKISLKNGKEIEVEKGLKVIDIAAKLSISLSKKALGAVVDGKVVELNYKINKDCKVEILTFEDEEGKKILRHTASHILAQAIKRLYPEVKLAIGPAIDSGFYYDVDAEFSFTPELLEKIEGKMNEIIKENIKLERFELPREEAIKFMEEKNEPYKVELIKDLPEDSIISFYKQGDFVDLCAGPHVPSTGRAKAVKLLSIAGAYWRGNENNKMLQRIYGTVFEKKSDLQDYLKLMEEAKKRDHRKLGKELDLFSIHEEGPGFPFFHPKGMVIRNTLQNFWREMHYKADYSEIMTPIILNEELWHRSGHWDHYKENMYFTKIDDGNYAIKPMNCPGSILVYKNDIRSYRDLPKRYAEMGVVHRHEKSGALHGLMRVRCFTQDDAHIFVTKDDIADEIIKVIDLIDNFYKIFGFEYFVELSTRPEDSMGSDEDWEAATEGLKNALKMVGLDYKINEGDGAFYGPKIDFHLKDCIGRTWQCGTVQLDFQMPEKFDLNYIGADGEKHRPVMIHRVVFGSIERFIGILIEHYAGAFPAWIAPVQVQVMNITDAQADYVAEVAKTLKENNIRVECDIRNEKIGYKIREAQMHKVPYMIILGDKEMKDKNISVRSRKEGDIGAMSLEDFILKLKEEIDKKISHV
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_SALPC
Sequence: MSEQIVTPESSTPVVLNNETKINLLDLNRQQMREFFKNLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLTNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDTIRDEIVPINKKYNIETFLGAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKETPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEVIDIKAI
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_CLOPE
Sequence: MVVGILIGIIILGVVGFIQYTLIQKASKNRVESLEKEASLTLEEAKREAESTKKEAILEAKEEVHKLRADLDKETRDRRNEIQRFERRLIQREESLDKKGEMLEKREDSINKKSIEIQELEERVQNLYGEQRAELERISNLSSEDARTLLLDEVRREIKHESAMLIKELETKAKEEADKKSREIITTAIQRCAADHVSETTVHVVALPNDEMKGRIIGREGRNIRTLETLTGVDLIIDDTPEAVILSSFDPIRREVARIALEKLIVDGRIHPARIEEMVERAIKDVENDIKEEGEQATFETGVHGLHPEIIKLLGRLKYRTSYGQNVLKHSIEVSYLAGLMASELGLDVNLARRAGLLHDIGKGVDQEYEGPHAVIGGELAKKYHESPAVVNAIAAHHGDTEMQTLEAVLVQAADAISAARPGARRETLEAYIKRLEKLEEIATSYEGVEKSYAIQAGREIRIMVKPDQVDDAGAIEMARNIVKKIEEQLEYPGQIKINVIRETRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SFSA_SYNSC
Sequence: MTGLSSPGDALLRFEPLTEGVLLKRYKRFLADVELSSGETVTAHCANTGPMTGVLIPGQRVRLRYAPSPKRKLAWTWEQAEVPGADGQHCWVGINTALPNRLIRATVEAGCLEAQLGAIARIRAEVAYGTNKRSRIDLLLTPAEQNPDQRPIYLEVKNTTWTDGSTALFPDTVTERGQKHLIELMGVLPDARAVLVPCLSRPDVTAFAPGDSADPRYGELFRQATNSGVEVLPCCFSFSADAVHWQGTRLVDLG
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.