PharMolix/UniProtQA huggingface dataset:
Protein: MEND_BACHK
Sequence: MNNHIEALSYYLGAFVDELTRLNVCDVVISPGSRSTPIALLMEQHEGMNTYLHVDERSAGFFALGIAKAKKRPVALLCTSGTAAANYYPAVCEAFHSRVPLIVLTADRPHELRDVGAPQAMNQINLYGTFVKQFTEMALPEASEAMYHYARMTTQRMIASACLAPQGPVHLNFPVREPLIPDFSLESLWDKGRGEYTGVVQQGNAVMPSEYVDSLVGRLSHMKKGLIICGDDSHSEIATFATQLAEKTGYPILADPLSNIRSGHHDKTMVIDCYDTFLRNELLKETWKPDVLIRFGGMPVSKALTQFIKKQTKAVHIVVDESGQWRDPALVATEVVQASDIAFCSALIEKMPVMKKNDWFRMWQHINEKTKETLREMETYDTAFEGRVITDIVRVLPEGATLFASNSMPIRDTDSFFFTSDKTIQVMANRGVNGIDGIISTALGASMICDPLVLVIGDLSFYHDLNGLLAAKLHELNITIVVVNNDGGGIFSFLPQYEKKEHFESLFGTPIGLDYEHVVTMYGGSFSRVNGWEQFREEVQKGATTEGLHVVEICTNRDENVTLHRKLWAKTQDVITTSLQGESK
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: GDPP1_MOUSE
Sequence: MAVPHHLQETSYLLPPDPEDWEKQGIPDFVYGQEDLVGKEVQWPRDSPSAVDTVPLSRFDSALRSAWRQRLELGLFRYRLEDLQTQILPGSVGFVAQLNIERGIQRRRPQNIRSVRQEFDPEQFNFNKIRPGEVLFRMQREPKGPATPKQEDDVLVVINVSPLEWGHVLLVPAPAQGLPQRLLPGVLRVGLEAVLLSLHPGFRVGFNSLGGLASVNHLHLHCYYLAHPLPVEGAPSTPLDPKGCIHLLQALPAPGFLFYTSGPGPDLEVLISRVCRATDYLSDREIAHNLFVTRGAPPGPTSSTSDLSGIRVILWARKSSFGIKESGAFNVALCELAGHLPVKTSQDFSSLTEAAAVALIQDCLLPETQAGEVRAALVALMAQEEL
What is the function of this protein?
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
What are the official names of this protein?
GDP-D-glucose phosphorylase 1.
What is the protein family that this protein belongs to?
Belongs to the GDPGP1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 31F13_MOUSE
Sequence: MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP
What are the official names of this protein?
Protein SPATA31F1-3, Protein FAM205A-3.
What is the protein family that this protein belongs to?
Belongs to the SPATA31 family.
Protein: ASIC2_DANRE
Sequence: MDLKEACGSEASRETESGGMGSLGGHSSWQSFAHRSTLHGLRFIFPYSSSSSSSSSYRSTSRRLLWSAALLASLVLLVLESTERLAYFLSYPHVTSVDAVVSGSLVFPAVTVCNLNAYRFTRLTQNDLYHAGELLALLDVHLQIPEPHLAEPHVLAFLTEKSNFTNYRPKPFSMREFTERVGHDLKEMMLYCRFQGQECSHQDFKTVFTRYGKCYMFNAAEEGKTLRTTMKGGTGNGLEIMLDIQQDEYLPVWGETEETAFEAGVRVQIHSQAEPPFVHELGFGVAPGFQTFVATQEQRLTYLPPPWGECVSRALDSGLFQVYSVSACRIECETRYIVENCNCRMVYMPGDSPYCTPEQYKDCAEPALAALSAVEGTNCICRSPCNMTRYNKELSMVKIPSKTSARYLEKKFNRSEKYITDNILVLDVFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTLLELFDYAYEVVKERLLDLLNREEEEESHGEDVSTCDPVVNHSESISHTVSVPLQTTLGTLEEIAC
What is the function of this protein?
Probable cation channel with high affinity for sodium.  In vitro, has no proton-gated channel activity.
What are the official names of this protein?
Acid-sensing ion channel 2, ASIC2, Amiloride-sensitive cation channel 1, neuronal, ZASIC2.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTNN_SALPK
Sequence: MKIGIIGAMEEEVTLLRDKIDNRQTITLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLASTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAESCIRELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPDAVAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSTLMVETLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: BPHA_PSEFK
Sequence: MSSSIKEVQGAPVKWVTNWTPEAIRGLVDQEKGLLDPRIYADQSLYELELERVFGRSWLLLGHESHVPETGDFLATYMGEDPVVMVRQKDKSIKVFLNQCRHRGMRICRSDAGNAKAFTCSYHGWAYDIAGKLVNVPFEKEAFCDKKEGDCGFDKAEWGPLQARVATYKGLVFANWDVQAPDLETYLGDARPYMDVMLDRTPAGTVAIGGMQKWVIPCNWKFAAEQFCSDMYHAGTMSHLSGILAGMPPEMDLSHAQVPTKGNQFRAGWGGHGSGWFVDEPGMLMAVMGPKVTQYWTEGPAADLAEQRLGHTMPVRRMFGQHMSVFPTCSFLPAINTIRTWHPRGPNEIEVWAFTLVDADAPAEIKEEYRRHNIRTFSAGGVFEQDDGENWVEIQKGLRGYKAKSQPLNAQMGLGRSQTGHPDFPGNVGYVYAEEAARGMYHHWMRMMSEPSWATLKP
What are the official names of this protein?
Biphenyl dioxygenase subunit alpha, Biphenyl 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: VRTN_AILME
Sequence: MTSREQLVQQVLQELQDAVESEGLEGLVGAALEAKQVLSSFALPTCREGGASPQVLEVDSVALSLYPEDAPRNMLPLACRGEGSLLFEAASVLLWGDVGFSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLCSEESPEMTSLPSATLEAIFDADVKATCFPSSFSNVWHLYALASVLQRNIYSIYPMRNLKIRPYFNRVIRPRRCDHVPATLHIMWAGQPLSSHLFRHQYFAPVVGLEEVEADGAPGPAPAPPALAPLPPPAKTLELLNQEPGLSYSHLCERYSVTKSTFYRWRRQSQEHRQKVAARFSAKHFLQDSFHRGGVVPLQQFLQRFPEISRSTYYAWKQELLGSGTCQALAPKEVQVLGELEQLPEEQMAKGLGCSSLAAASPSMVLMQRAKSYLEHCISLNTLVPYRCFKRRFPGISRSTYYNWRRKALRRNPSFKPAPALSTPGAPQPASVPEEALLPWKGEGGEGAGKATAGGPPAPHEFLPPKVPLSRWQRRLRRAARKQVLSGHLPFCRFRLRYPSLSPSTFWVWKSLARGWPRGLSKFQTQAPALGKGGLREAKEKQEKEAGRDVTAAMAPPAGTPLHVGASPGEDPGKAQGGPSGEGAMAQGRPHSRSLSSRPVAEAAVGGGDGQVLVMDMLATTKFKAQAKLFLQKRFQSKSFPSFKEFSALFPLTARSTYYMWKRALYDGLTLVDG
What are the official names of this protein?
Vertnin.
What is the protein family that this protein belongs to?
Belongs to the vertnin family.
Protein: RPOB_NANDO
Sequence: MLRDANEGMSTIPGFSQIQFEGFCRFIDRGLMEELNKFPKIEDTDQEIEFQLFVETYQLVEPLIKERDAVHESLTYCSELYVPAGLIWKTGKDIQEQTIFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVPSSAMGSNLKEIIDNVCYPEIFLSFPNDKEKKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPHNITFLLPRDVLAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQFGLAMVRLENAVRGTIGGAIRQKLIPTPHNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKSSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGHWGSLERPFYEISERSKGVRVIYLSPSIDEYYMVTAGNSLALNHGIQEEQVVPARYRQEFLTIAWEQIQLRSIFPFQYFSVGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGVSAIAEHEGKIIYTDTDKIILSGNGATLSIPLVMYQRSNKNTCMHQKPQVSRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYGDIYTSFHIRKYEIQTHVTSQGPERITNEIPHLEAHLLRNLDRNGIVMLGSWVETGDILVGKLTPQVAKESSYAPEDRLLRAILGIQVSTAKETCLKLPIGGRGRVIDVRWIHKKGGSSYNPETIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGTPVDMVFNPLGVPSRMNVGQIFECSLGLAGGLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFAQPVIIGKSYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPNPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UPPP_WIGBR
Sequence: MKEILIIIILGIVEGITEFFPISSNGHLILINYIFNIDKENIQNIIKIIQIGPIFSIILLFKEKIKKSITFFYFNINNIKKKLILILFNLVLSCIPISILGFMFYKKLEEFYSPKYISYFLILGSIFFILSEFISLKKIKIDNFKKISFLKYFIIGSSQCFSLLPGVSRLGITISIGLILNIDRYVLFKFSMILFSSIMPAVLILEVYKNFFYLKENIFFVIIGVMSSFLTSLIFGRTAIKIMKNTSLIIFAIYRIFIACIILFTCN
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRAF7_HUMAN
Sequence: MSSGKSARYNRFSGGPSNLPTPDVTTGTRMETTFGPAFSAVTTITKADGTSTYKQHCRTPSSSSTLAYSPRDEEDSMPPISTPRRSDSAISVRSLHSESSMSLRSTFSLPEEEEEPEPLVFAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRCALKSEKCPVDNVKLTVVVNNIAVAEQIGELFIHCRHGCRVAGSGKPPIFEVDPRGCPFTIKLSARKDHEGSCDYRPVRCPNNPSCPPLLRMNLEAHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQKDQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASMLNDELSHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSHNVLFSGSLKAIKVWDIVGTELKLKKELTGLNHWVRALVAAQSYLYSGSYQTIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSRGRLFSGAVDSTVKVWTC
What is the function of this protein?
E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3.  Potentiates MAP3K3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators (PubMed:14743216).  Induces apoptosis when overexpressed (PubMed:15001576).  Plays a role in the phosphorylation of MAPK1 and/or MAPK3, probably via its interaction with MAP3K3.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRAF7, RING finger and WD repeat-containing protein 1, RING finger protein 119, RING-type E3 ubiquitin transferase TRAF7, TNF receptor-associated factor 7.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRAF7 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Note=Colocalizes with MAP3K3 to vesicle- like structures throughout the cytoplasm.
Protein: MRAZ_LIMF3
Sequence: MFMGEYTHTIDDKGRLIIPAKFRSQLGDDFIITRGLDHCLYGYPLIEWQAVQQRLASLPSTNANARKLVRYFYSAACECQFDKQGRVNLPANLMQHAYLERDCVVIGVASHFEIWDAERWASYQDAAASDFDQLAAGFDGLSF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HSLV_XANC5
Sequence: MDPSQNPNIVHATTIISVRRGGHVAVAGDGQVTLGHTVMKGNARKVRRLGREGQVLAGFAGAAADAFTLFELFEAKLDKHGQLTRAAVELAKDWRTERRLGKLEALLAVADKETSLIISGTGDVIEPEDGIIAIGSGGSYALSAARALLAHTELDAKTIATEAINIAGDICIYTNRNVVVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMF_PSEA7
Sequence: MPRPSSPRPDAERKSASPLHPRNRHLGRYDFPGLIAGNPELERFVIVNPYGKPSIDFADPLAVKAFNRALLQQFYDVREWNIPEGYLCPPIPGRADYLHYLADLLGASHDGVIPRGTGLRALDVGTGANCIYPLLGHHEYGWRFVGADIDPQSLASAAAILAANPRFAAAIELRRQPDRRHIFEGLVDSAERFDMTLCNPPFHASLDEATRGSRRKWKNLGKLDPGRTLPLLNFGGQGAELHCEGGEAAFLASMAGESRAFATQVFWFTTLVSKASNLPNLQERLKTLGASDIRVVDMAQGQKQSRFVAWTYLDKKQRRAWRRERWSAAVPLGE
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1038_BRUAB
Sequence: MSDKTPRKPTAFRLEQPARVSAASEQEEPRRPRAVKDLEQITPQADVFDLTDDEAAELEILDPAFEAPERKGWSLSRILFGALGILVSFAIGIWTEDLIRALFARADWLGWTALGVAMVALAAFAAIILRELVALRRLASVQHLRKDAADAAERDDMAAARKAVDALRTIAAGIPETAKGRQLLDSLTDDIIDGRDLIRLAETEILRPLDREARTLVLNASKRVSIVTAISPRALVDIGYVIFESTRLIRRLSQLYGGRPGTLGFIKFARRVIAHLAVTGTIAMGDSVIQQLVGHGLASRLSAKLGEGVVNGLMTARIGIAAMDVVRPFPFNAEKRPGIGDFIGDLARLNSDRNARK
What are the official names of this protein?
UPF0283 membrane protein BruAb1_1038.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GHT7_SCHPO
Sequence: MRDFQSRFADRYNQITNSYSYSSSRQGLITGMVNVGSFFGCLLSSPVADKIGKRLSIIVWTTVYLIGIIIQVTTVPSWVQILVAKIWTGLSIGALSVITPGYQSEVAPAIMRGAIVTTYQLFITLGIFIAACINMGTHKYSHGTTAQWRISIGINLLWGIITLVGIIFLPESPRYLIAIGKDDEALKIMCYNNDLPLEHEIIQTEYHTIKSDCDAELAGGPARWPEIFNANIRYRTFLGMAVMMFQQLTGANYYFYYGTQVFRGTGMDSPYLAALIPDAVNCGCTFGAIFVLEFFGRRSPLIVGGIWQYICFFIYAAVGDRALYHKNGTSNHRAGAVMIVFSCLFIFSFSQTWAPAAYVIVGESYPVRYRSKCAAVATSANWFWNFLISFFTPFITNSIGFKYGYIFASCNLTGAAIIFLFVHETKGRTLEEINTMYASNLKPWMPHPEGYREFGREQNNATLKSHIGLNGETTELIENTDNQGDSGSFQTSTPDDSRPEQNQASATYIRPDKREPRL
What are the official names of this protein?
Probable high-affinity hexose transporter ght7, Hexose transporter 7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: QCRC_CORDI
Sequence: MTNAKKVRARRKIRRTAAGAMALAVGLTGAGILVNAVTPDAQVATAQQDEQALIQEGKDLYDVACITCHGANLQGVKDRGPSLIGVGSGATYFQVHSGRMPMLRNEAQAKRKTPRYSEAQTLAIAAYVEANGGGPSIVYNKDGSVAMESLRGANYKDGIDPADVARGSDLFRLNCASCHNFTGRGGALSSGKYAPVLDPANEQEIYQAMLTGPQNMPKFSDRQLSADEKKDIIAYIKSAKETPSQGGWNLGGLGPVTEGMMMWLVGIVVLVAAAMWIGSRS
What is the function of this protein?
Cytochrome c1 subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
What are the official names of this protein?
Cytochrome bc1 complex cytochrome c subunit, Cytochrome bc1 reductase complex subunit Qcrc, Menaquinol--cytochrome c reductase cytochrome c subunit.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MPH3_YEAS8
Sequence: MKNLSFLINRRKENTSDSNVYPGKAKSHEPSWIEMDDQTKKDGLDIVHVEFSPDTRAPSDSNKVITEIFDATEDAKEADESERGMPLATALNTYPKAAAWSLLVSTTLIMEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMAGEIVGLQLTGPSVDLVGNRYTLIIALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQWILPVPLALGIFFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKVTIDKEKRLTSKEGSYSDCFEDKINRRRTRITCLCWAGQATCGSILIGYSTYFYEKAGVSTEMSFTFSIIQYCLGICATFLSWWASKYFGRYDLYAFGLAFQTIVFFIIGGLGCSSTHGSKMGSGSLLMAVAFFYNLGIAPVVFRLVSEMPSSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKWNWGAKSGFFWGVLCFCTLIWAVVDLPETAGKTFVEINELFKLGVSARKFKSTKVDPFVVKNPPKDVSHNDPKGDIEASIAEE
What is the function of this protein?
High-affinity uptake of maltose and maltotriose.  Also transports alpha-methylglucoside, glucose and turanose but not melezitose or trehalose (By similarity).
What are the official names of this protein?
Alpha-glucosides permease MPH3, Maltose transport protein 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ALG6_MOUSE
Sequence: MESWPWMAVVVLLGLTVRWTVSLSSYSGAGKPPMFGDYEAQRHWQEITLNLPVKQWYFNSSDNNLLYWGLDYPPLTAYHSLLCAYVAKFINPDWVALHTSRGYESQAHKLFMRATVLAADLLIYVPAVLLYCYSLKEISPKRKIASALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGVSWDWDLLGSLAFCLALNYKQMELYHSLPFFCFLLGKCFKKGLKGKGLALFIRIACTVLASFLLCWLPFLTEREHALQVVRRLFPVDRGLFEDKVANIWCSVNVFLKIKDTLPRHIQIAISFCFTLLSLLPACIKLTVRPSCKGFRFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLTEIPFMSTWFLLVSTFSMLPLLLKDELLLPSVVTVMAFVIACGTFFPMLENTSEEQLQLKSFAVSVRRHLPGFTFLPRIMQCLFLSSVITMVLLTILSVTLDPPQKLPDLFPVLICFVSCVNFVFFLVYFNIVIMWDSKNGRNRKKIE
What is the function of this protein?
Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity).
What are the official names of this protein?
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 6 homolog, Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG6/ALG8 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: OVCH_HALRO
Sequence: MIVTFVALALSCCTPQVTADCGLRPRLQSAIITGRIVGGEMAKLGEFPWQAAFLYKHVQVCGGTIIDTTWILSAAHCFDPHMYKLQSIKKEDALIRVADLDKTDDTDEGEMTFEVKDIIIHEQYNRQTFDNDIMLIEILGSITYGPTVQPACIPGANDAVADGTKCLISGWGDTQDHVHNRWPDKLQKAQVEVFARAQCLAAYPESTENMICAGLRTGGIDSCQGDSGGPLACPFTENTAQPTFFLQGIVSWGRGCALDGFPGVYTEVRKYSSWIANYTQHLLQDRNADVATFTITGDPCSSNGSIISGSEGDFSSPGFYSGSYTDNLDCKWIIQIPDIGSRIQLSFTEFGVEYHTFCWYDDVKVYSGAVGNIASADAADLLGSHCGMNIPSDLLSDGSSMTVIFHSDYMTHTLGFRAVFHAVSADVSQSGCGGIRELLTDHGEFSSKHYPNYYDADSICECFITAPTGKTIELNFLSFRLAGSDCADNVAIYDGLNSSYPRIIRLCINQGFNVTVPSSSNTMFVSFKTDGQVQDVGFEAYYYFSSNGNSTDDTDYSQCGFSSTPINADQTAARIVNGDIAIAGSWPWQISIRLCDTCNHYCGGSIISPSWIVTAAHCIESSAHITYIRAGDFDRFTIEISETIVPVAQIFIHPDYQKDLPNNADIALLKLANPLSYSSTIRPVCFPSQISTIPEENAECYVTGWGLTEENVMAQKLREAKLPLMPYDQCLNVYTSYVLNENMLCAGNISSGIDTCLGDSGGPFVCRKSRNDPWILYGVSAFGRECGSSRYPGVYTKVTRYIDWIIATANVSTVTSVVEEHDPTEFEQGCIQLLVLSNHEGDLSSPEYPELYGEGMLDCQWKIVLMDRTKSLNINFRFSHSQQDTAAACSLANIRISESYSDGTVGRQYGPYCGSSESILISSLHDLVVSLHNSQSQVKIGLKLEYRLEELEQSGCGQLKHLIENKGNFSSINYPNIYSANSHCEWYLHASIATHYLQISLSQFSLENAYQCRYDFLTVIDVTENGNISHGPYCGNSIPHVITGHGLFHIKFRSDASLNYKGFFASFVELNERPQEESGCGGVKFLNGTNGTFQTAGFPLAYEANLDCTWVIEVEDGYKVRLNFQQFSLESSSSCKYDWAMLYNGEFAFEAQRIDTLCGYDVKLEDIFESTSNVMRIDFHSDFSFNKQGFLAMYTAVSPGSSRSSVHQRENHLQEKRSGGCQDSIFTDEEGVIEYKQGDHTGNTRCLFRILTNHLHVIRLWLRKLSSLNLHENDSIKIYDKIDVDDIYSGVVKPVFQFTGIIGYLDSLPAYLDYNGGEISMLFSSDGQHGDTSFELIYKLMQDKSSTTNPKQLWNDHHGKWPWMVSLFGSSKYYFCSGVIISSRWIATAATCNLRSSEIHIIFPEGTNPKKIWEVEKIVVHPEFKMIYNVPQNDLALIQLVDPIEHIPPVCLPVASNIYSDCHVLKIPRLAGSAAFPDIVRISSVDTLAHDICMREWHLRITDDMLCGRINGTNSCQRDVGGPLVCQSPSDDAWYFVGISSWGPKICNDNTAHHRLPDVYVSVAYFLKWITKIIQ
What is the function of this protein?
May be responsible for elevation of the vitelline coat at the late developmental stage of oogenesis and during fertilization in ovarian eggs.
What are the official names of this protein?
Ovochymase, HrOVCH.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NU3M_CANLU
Sequence: MNVMLTLMTNVTLASLLVLIAFWLPQLNIYTDKTSPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWASQTNKLTTMLIMALLLISLLAASLAYEWTEKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNAK_LACP3
Sequence: MSKVIGIDLGTTNSAVAVLEGNQPKIITNPEGNRTTPSVVAFKDGEIQVGEVAKRQAITNPDTIVSIKRHMGEANYKVKVGDKEYTPQEISAMILQYIKKFSEDYLGEPVKDAVITVPAYFNDSQRQATKDAGKIAGLNVQRIINEPTASALAYGLDKGDKDEKILVYDLGGGTFDVSILQLGDGVFEVLSTNGDTHLGGDDFDNKIIDWLVAEFKKDNNIDLSKDKMAMQRLKDAAEKAKKDLSGVTQTQISLPFISAGPNGPLHLERTLTRAQFDEMTADLVAKTKIPVENALKDAKLTNADIDKVILNGGSTRTPAVQEAVKQWTGKDPDHSINPDEAVALGAAIQGGVISGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADSQPAVDIHVLQGERPMAADDKTLGRFELTDIPPAPRGVPQIEVKFDIDKNGIVQVSAKDLGTGKSQNITIKSSSGLSDEEIERMKKEAEENADADEKRKEEVDLKNDVDQLLFQTDKTLKDVDGKVPEEDIKKVKDAQEALKKAQQENNLDDMKQKRDDLSKLVQDMTVKLYENAQKNQQAQGGPASGAATDAGAAQGSDDKKSDDDTINGDYKDVSDDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MT2B_ORYSJ
Sequence: MSCCGGNCGCGSSCQCGNGCGGCKYSEVEPTTTTTFLADATNKGSGAASGGSEMGAENGSCGCNTCKCGTSCGCSCCNCN
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein 2B, Class I metallothionein-like protein 2B, OsMT-I-2b, OsMT2c.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: PLMN_CANLF
Sequence: ASDCMFGNGKGYRGKKATTVMGIPCQEWAAQEPHRHSIFTPETNPQAGLEKNYCRNPDGDVNGPWCYTMNQRKLFDYCDVPQCVSTSFDCGKPQVEPKKCPGRVVGGCVANPHSWPWQISLRTRYGKHFCGGTLISPEWVLTAAHCLERSSRPASYKVILGAHKEVNLESDVQEIEVYKLFLEPTRADIALLKLSSPAVITSKVIPACLPPPNYVVADRTLCYITGWGETQGTYGAGLLKEAQLPVIENKVCNRYEYLNGRVKSTELCAGNLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGIMRNN
What is the function of this protein?
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation.  In ovulation, weakens the walls of the Graafian follicle.  It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5.  Cleavage of fibronectin and laminin leads to cell detachment and apoptosis.  Also cleaves fibrin, thrombospondin and von Willebrand factor.  Its role in tissue remodeling and tumor invasion may be modulated by CSPG4.  Binds to cells (By similarity).
What are the official names of this protein?
Plasminogen.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasminogen subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface (By similarity).