PharMolix/UniProtQA huggingface dataset:
Protein: FOLD_HELMI
Sequence: MTAQYIDGKAIAAQLRAEIKAEVASLREQGIVPKLAVILVGDDPASVVYARSKEKAAANLGIAFELFTLPGDTTEAALLALIERLNADAAVHGIMVELPLPKQISKEKVLEAIHPLKDVDGVHPLNRGYLMAGQPGLVPATPMSCMELLARSGVELAGKRVVIIGRGETVGKPLFFLLLRRNATVTVCHTRTKDLAAEVRRAEIVIAAAGKAGLVTGEMIAPDAVVIDAGINEGEDGNIVGDVKTAEAAERASLISPVPGGVGACTTALLFRNVLFGLKLQGGMAHE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DAPB_MYXXD
Sequence: MIRTVITGITGRMGSTLLRLALDSGDLRVVGGTARPGSASVGQDAGVATRLGPVDVTVVDSLERALDAAQADVVIDFTSAELSVAHAKVCAARGVALVVGSTGFTPEASAALAESAKAVPIVAAPNMSVGVNLVIRMAAELARVLGPGFDVEVLEAHHRMKKDAPSGTALRLAEVLTEALGRTQEDLTFARHGQIGARPAREIGVQTLRGGDVVGEHTVYFLGEGERIELTHRATNRDQFAAGALRAARWVAGRAPGLHDMADVLGFQRTS
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_BORGP
Sequence: MIKRLNNFFEKINIKPQTKNLINYTTYKIGNISKLFLIPKNIQEAENIFKAAIEEKITLFILGGGSNILVNDKEELDFPIIYTGHLNKIEVHDNKIVAECGANFENLCKIALNSSLSGLEFIYGLPGTLGGAVWMNARCFGNEISEILKKITFINDKGKTICKEFKKEDFKYKVSPFQNKNFFILKTELNLKKENKKIIEEKMNKNKQARINKGHYLFPSSGSTFKNNKSFLRPSGQIIEECKLKGLSVGGAEVSKYHGNFIININNATSNDIKSLIEKVKTEVYSKTGLLLEEEVLYIGFKNQKS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_ECOSE
Sequence: MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAIDETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMVEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AK200_DROME
Sequence: MGKAQSKRSIDITTDPKKVGEGDEVAGKVEKIDVDQKTDAPAVNGDAATPKEGGDEAAAVEKKETEEHSENDKDLTTEKSAAVAEGGDAVAETAKGEEGSPKEAAAGEDITPLADESIKSKSKKDKVKKKWSFRSISFGKKDKQKPAKSEEATSPTSGTTSPTTAEAEAAPAGDAAVAEPSVATNGEAEKPAETATATSEPASKDEKPAENGSATEQEKQANGETEKAAPAPSTVEEAAKPKPAEEPATVTATESNTTATEEVPVKESQPEPEVVTNGHGAGEALTNGSSNGLAESPVTETAPVADNIPSNVDDEPPHQNGTNGTTTPPPTPVATEIEKGQQIEASSEVIETVTPSQAEEEVVAAIIKAVSSEPEAETETETEAEGFVLVAPVSTEVEVPVSISPIEPVAEVSQVKIEPLVEIPEVEAKSVADVSEADTESVPKVSELKTEVSEIEFESVIVETRSSSPPPPLPKSPPPSRVSAFVLSEDVIEEQVTPNVPEVNDVKPDEIEQQAISIVAEITEQAAEIVTEQEKQQEEAKVDSVPETIEESSSTVVVEEVLPVQNDEVTAPSPTPDDVQKPIEDQDTPDEKESYPVPDPIDPAAVNDEVAVTEAVDCEVEKETGSISSNVAESSSVSDEQAAIENQVEILEEQTVAVEETTEQETSDQQVISEEAHSDNDKENEIDLVENIISDLDAPITKAGGDLLVELDARSAEQEGESNNKVDLAKDLKEKNAAAADVTTQEQLPVTCE
What is the function of this protein?
Scaffolding protein involved in the regulation of PKA signaling and anchoring to the actin cytoskeleton integrating signals propagated by cAMP, diacylglycerol and calcium (PubMed:10480936, PubMed:10480937, PubMed:12223401).  Contributes to the maintenance and regulation of cytoskeletal structures in germline via PKA-mediated signaling (PubMed:12223401).  As part of ethanol response in the glia, mediates ethanol-induced structural remodeling of actin cytoskeleton and perineurial membrane topology by anchoring PKA to the membrane of perineurial glia (PubMed:29444420).  In specific tissues such as eye and thorax, promotes N/Notch protein stability by inhibiting Cbl-mediated ubiquitination and lysosomal degradation pathway of N/Notch in a PKA-independent way (PubMed:29309414).  In the circadian brain neurons evening cells (E-cells), might have a role in circadian pacemaker synchronization by playing a redundant role in signaling downstream of the G protein-couple receptor Pdfr (PubMed:23929551).
What are the official names of this protein?
A-kinase anchor protein 200.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Lipid-anchor. Cytoplasm, cytoskeleton.
Protein: FLOT2_HUMAN
Sequence: MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEKELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPASVHALTGVDLSKIPLIKKATGVQV
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.  May be involved in epidermal cell adhesion and epidermal structure and function.
What are the official names of this protein?
Flotillin-2, Epidermal surface antigen, ESA, Membrane component chromosome 17 surface marker 1.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome. Membrane; Lipid-anchor. Note=Membrane- associated protein of caveolae.
Protein: GLGX_SALPK
Sequence: MTQLAIGEATPHGATYDGHGVNFTLFSAHAERVELCVFDSRGNERRYDLPGRRGDVWHGYLAGARPGLRYGYRVHGPWQPAQGHRFNPAKLLLDPYARRVEGELKDHPLLHGGHDEPDYRDNAAVAPKSVVISDHYDWEDDAAPRTPWGKTVIYEAHVKGLTYLHPELPQEIRGTYKALGHPVMVAYFKQLGITALELLPVAQFASEPRLQRMGLTNYWGYNPMAMFALHPAWASSPETALDEFRDAVKALHRAGIEVILDIVLNHSAELDLDGPTFSLRGIDNRSYYWIRDDGDYHNWTGCGNTLNLSHPDVVEYACECLRYWVETCHVDGFRFDLASVMGRTPTFRQDAPLFAAIKACPVLSTVKLIAEPWDIGEGGYQVGNFPPPFAEWNDHFRDAARRFWLPRNLTTGEFACRFAASSDVFKRNGRAPGASVNLLTAHDGFTLRDCVCFNQKHNEANGEENRDGTNSNYSDNHGKEGLGGPLDLMERRRDSIHALLATLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNALTWLDWQQANRGLTTFTAALIRLRQQIPALTGNSWWEEGDGNVRWLNKNAQPLSADEWQNGPKLMQILLSDRFLIAINATLEVTDIVLPEGEWRAVPPFAGEDNPVITAVWQGPAHGLCVFQRG
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: RSMH_DESDA
Sequence: MIQTMSDTTEPTRHVSVLPVETLAALDPRAGGRYLDGTLGMGGHASAILSSAPGIELCGLDRDEEALALAGQRLSSFGGRAHLFHCRYSDFAEALNELGWDKVDGALLDIGVSSLQLDEAERGFSFYGDGPLDMRMDQNSAQPSAWHWVNRESFDKLKDCIATLGEEPQAGRIARAIVDARQKNTIDTTGQLAALVERAYPAAWRAKARRHPATRTFQALRMAVNDELGELRRFLDQILTWLPIGGRLAVITFHSLEDRMVKQAMRHWVEGCRCPRHIPRCICGHQPEVRILHKKPVQAGPEELAANSRAGSAKLRAVEKIAEDSGS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_MANOF
Sequence: MEEIQRYLQPDSSSSQQHNFLYPLIFQEYIYALAHDHGLNRNRSILLENPGYNNKFSFLIVKRLITRMYQQNHFRISTNDSNKNPFLGCNKSLYSQMISEGFAFIVEIPFSLRLISSLSSFEGKKIFKSHNLRSIHSTFPFLEDNFAHLNYVLDILIPYPVHLEILVQTLRYWVKDASSLHLLRFFLHEYWNLNSLITSKKPGYSFSKTNQRFFFFLYNSYVYESESTFVFLRNQSSHLRSTSFGALLERIYFYGKIERLVEVFAKDFQVTLWLFKDPFMHYVRYQGKSILASKGTFLLMNKWKFYLVNFWQCNFSLCFPTGRIHINQLSNHSRDFMGYLSSVRLNPSMVRSQMLENAFLINNGIKKFDTLVPIIPLIGSLAKANFCTVLGHPISKPVWSDLSDSDIIDRFGRICRNLFHYYSGSSKKKTLYRIKYILRLSCARTLARKHKSTVRTFLKRSGSELLEEFLTSEEQVLSLTFPRASSSLWGVYRSRIWYLDIFCINDLANYQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UVRB_STAAW
Sequence: MTMVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_PROM2
Sequence: MLLSELSHPNQLHGLTVSQLEEIACQIRERHLQVVSTSGGHLGPGLGVVELTLALYQTLDLDFDKVVWDVGHQGYPHKLITGRFSQFDSLRQQNGVAGYLKRSESKFDHFGAGHASTSISAALGMAIARDRKGDNYKCVAVIGDGALTGGMALEAINHAGHLPNTPLVVVLNDNDMSISPPVGALSSYLNKVRHSPPLQFLSDSVQESVKNIPLIGKDIPEELKNIKGSVRRLAVPKVGAVFEELGFTYMGPIDGHDIGNLINTFNAAHKLKKPVLVHVVTTKGKGYPYAEADQVGYHAQSSFDLTTGKSIPSKKPKPISYSKIFGQTLLKICEQDSKVVGITAAMATGTGLDILQKNIPDQYIDVGIAEQHAVTLAAGMSCDGLKPVVAIYSTFLQRAFDQLIHDVGIQNLPVSFVLDRAGIVGADGPTHQGQYDISYMRSIPNFVLMAPKDESELQRMLITSINHKGPTALRIPRGSGLGVAVMDEGWEPLNIGEAEILEEGNDILIIAYGSMVASALETAELLKAKNINSCIVNARFVKPLDKKLIMPLASRIQKVVTMEEGTLIGGFGSAIVELFNDNEINIPVYRIGIPDVLVDHASPDQSKEKLGLMPNQMADNIIKKFDLNN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: Y531_BORBU
Sequence: MIKKFLLFAMLNIFLTNKAHSNEEIIEISTEIQKEKYIPFLISRGKTQLEDLVKYTLEINPELDKNYVNTVAKTYIDESLIEGVNYDIAYAQMLLETGALKFNGIVSKEQHNFSXIGATNNLTKGNSFSNITEGIKAHIQHLKAYASKQNIKSNMVDPRFYLVKRGSAPTIYDLTGKWAKDKLYDKKLKKILLELLEYNNANKS
What are the official names of this protein?
Uncharacterized protein BB_0531.
Protein: ATPF_STRMK
Sequence: MNINFTLLAQALAFAGLIWIIATKIWPPLMNAIEERQQKIAEGLAAADRSQKDLAQAQEKVNEALKEARTKANEIIDQAHARANQIVDAARNEAITEATRQKELAQAEIDAAANRAREDLRKQVSALAVTGAEKLLKREIDANAHKALLDELASEI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NUSB_BURO0
Sequence: MKKSARRQSRELATQGLYQWLLSNAPSGEIDAQLRGALGYDKADKELLEAILHGVIREHATLVEALAPSLDRPIDQLSPVERAVLLIATFELTHHVETPYRVIINEAVELAKTFGGSDGYKYVNGVLDKLAAKLRPAETQARRNG
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NDK_SYNS9
Sequence: MAERTFVAIKPDGVQRGLVGEILGRFERKGFKLVGLKQITPSRALAEEHYGVHKERPFFAGLVGFITSGPVVAMVWEGDGVIASARKLIGATKPLESEPGTIRGDLAVNIGRNVIHGSDAPETAEFEIGLWFQPSELNDWSPSDQAWRVED
What is the function of this protein?
(Microbial infection) Catalyzes the phosphorylation of dZDP to dZTP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_THEKO
Sequence: MSLLAKIVDGKNLSFEEAYELFNELKGSDGVLIGAYLAALQTKGYTGEELAGLARAMRDSAVKLDLGKVADTAGTGGDGSSTINVSTASALILSAFTRVAKHGNVSITSKSGSANVLEALGLNIRVSPERAREMVESTNFTFIFAPAYHPALRPIMPVRKALGIKTVFNVIGPLANPADPAYQVVGVNSPELLEPVAEALEFLGVERALVVHGSGMDEVSPHRETLVLEVGNGVERYTLSPEDFGIEPVKPLPCSSPEESAARIKAVLGGSGRREDRDFILVNASAALYASGVAEDFREGLEMAREALGQGMLEKLEEIACLSKS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RL25_PECAS
Sequence: MITIKAEARQGQGKGASRRLRSAGKFPAIVYGGSEAPVSIELDHDSVKNQEVKEGFYGETLILSIDGKEVQVKVQAVQRHVYKPKLTHIDFVRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: MAG_MOUSE
Sequence: MIFLATLPLFWIMISASRGGHWGAWMPSTISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAKSLYLDLEEVTPGEDGVYACLAENAYGQDNRTVELSVMYAPWKPTVNGTVVAVEGETVSILCSTQSNPDPILTIFKEKQILATVIYESQLQLELPAVTPEDDGEYWCVAENQYGQRATAFNLSVEFAPIILLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNETEREFVYSERSGLLLTSILTIRGQAQAPPRVICTSRNLYGTQSLELPFQGAHRLMWAKIGPVGAVVAFAILIAIVCYITQTRRKKNVTESSSFSGGDNPHVLYSPEFRISGAPDKYESEKQRLGSERRLLGLRGESPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK
What is the function of this protein?
Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (PubMed:7533044, PubMed:12089450, PubMed:27922006).  Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination (PubMed:7516497, PubMed:9262180, PubMed:9482781, PubMed:9482783, PubMed:9469574, PubMed:10625334).  Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2 (PubMed:26335717).  Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane (PubMed:15953602, PubMed:19158290).  Negative regulator of neurite outgrowth that inhibits axon longitudinal growth (PubMed:19158290, PubMed:27922006, PubMed:12089450).  Negative regulator of neurite outgrowth; in dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides (PubMed:17640868).  In cerebellar granule cells the inhibition is mediated via binding to neuronal gangliosides (PubMed:17640868).  In sensory neurons, inhibition of neurite extension depends only partially on RTN4R, RTN4RL2 and gangliosides (By similarity).  Inhibits axon outgrowth by binding to RTN4R (PubMed:12089450).  Preferentially binds to alpha-2,3-linked sialic acid (PubMed:7533044, PubMed:27922006).  Binds ganglioside Gt1b (PubMed:27922006).
What are the official names of this protein?
Myelin-associated glycoprotein, Siglec-4a.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft.
Protein: RS11_MAGMM
Sequence: MAKAQKGARTKKKERKNIASGIAHIHSTFNNTLITITDTHGNSISWGSAGAQGFKGSRKSTPFAAQMAAENAGKKAMDHGMRNLEVRLKGPGSGRESALRALAAIGFNISHVQDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GLO1A_ORYSJ
Sequence: MLPYATAAEAEAALGRAMTAAESLWFRYSAGIPDYVLFWHNILFLFVVFTLAPLPVALLELRAPAAVGPFKLQPKVRLSREEFFRCYRDVMRLFFLVIGPLQLVSYPTVKMVGIHTGLPLPSLGEMAAQLLVYFLVEDYLNYWIHRLLHGEWGYEKIHRVHHEFTAPIGFAAPYAHWAEVLILGIPSFVGPALAPGHMITFWLWIVLRQMEAIETHSGFDFPFNLTKYIPFYGGAEYHDYHHYVGRQSQSNFASVFTYCDYLYGTDKGYRYHKAYQAKMKALGQTEGEKADSNGLSYAKLD
What is the function of this protein?
Aldehyde decarbonylase involved in the conversion of aldehydes to alkanes.  Core component of a very-long-chain alkane synthesis complex.
What are the official names of this protein?
Very-long-chain aldehyde decarbonylase GL1-10, Protein GLOSSY 1-10.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TM143_HUMAN
Sequence: MTVELWLRLRGKGLAMLHVTRGVWGSRVRVWPLLPALLGPPRALSSLAAKMGEYRKMWNPREPRDWAQQYRERFIPFSKEQLLRLLIQEFHSSPAEKAALEAFSAHVDFCTLFHYHQILARLQALYDPINPDRETLDQPSLTDPQRLSNEQEVLRALEPLLAQANFSPLSEDTLAYALVVHHPQDEVQVTVNLDQYVYIHFWALGQRVGQMPLKSSVGSRRGFFTKLPPAERRYFKRVVLAARTKRGHLVLKSFKDTPLEGLEQLLPELKVRTPTLQRALLNLMLVVSGVAIFVNVGMVVLTDLKVATSLLLLLFAIFMGLRASKMFGQRRSAQALELAHMLYYRSTSNNSELLSALALRAQDEHTKEALLAHSFLARRPGGTQGSPEETSRWLRSEVENWLLAKSGCEVTFNGTRALAHLQALTPSMGLYPPPGFPKLDPVAPITSEPPQATPSSNIS
What are the official names of this protein?
Transmembrane protein 143.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UPPP_SALPK
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRQLFGLIGIHFGRPLQREGESKGRLTLIHILLGMIPAVVLGLVFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATVLDLYKSWSFLTAADIPMFAVGFVTAFVVALIAIKTFLQLIKRISFIPFAIYRFVVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATK_HORVV
Sequence: MEKFEGYSEKQKSRQQYFVYPLLFQEYIYAFAHDYGLNGSEPVEIVSWNNKKFSSLLVKRLIIRMYQQNFLDNSVNHPNQDRLLDYKIFFYSEFYSQILSEGFAIVVEIPFSLRELSCPKEKEIPKFQNLRSIHSIFPFLEDKFLHLDYLSHIEIPYPIHLEILVQLLQYRIQDVPSLHLLRFFLNYYSNWNSFITSMKSILFFQKENKRLVKFLYNSYVSEYEFFLLFLRKQSSCLPLAYSGTFLERIHFSRKMEHFGIMYPGFSRKTLWFFMDPLIHYVRYQGKAILASKGSFFLKKKWKCYLINFWQYYFFFWTQPRRIHINQLANSCFDFMGYLSSVPKSPLLVRNQMLENSFLIDTRMKKFDTIVPATLLIGYLSKAQFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYHSGSSKKRTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSAFLEEFFTEEEQVFSLMFTKTTLFSFSGSHTERIWYLDIIGINDLVNPLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: INO80_SCHPO
Sequence: MDPSRETFDGSTRDSYKPPNGAEMMGQSELNTQNRIPYNTSANNRNWQIPLYWQQRGNEFQASPPPPLGYVTPEYGATGTPVNANNASRVDYATTAANVPEEYANDYSSELAYIHNVNDMPHVDGLSNHSPATQPDLFETPAQSDPILFSSYPHAAQARVDPSISKDLYNMVPRPDANTVSPHAARSASSLPVPKEASETPFRDASTDLFDEHAHAAPMHSSISISTLLSDSDRYEPHVSLTENISPVMAPSIDARLSQTILRGLPPAQKLSPNSSQSQITHNRRKHKLPLNATTNNSVVLTPDTSPLLDSDEVVSDDDSNEQQTMMMKFNYLQHLRNKRDEAVHAEKRRLLDIRGSIHDRLVCRYENRYNKLHASEYNHHHDWAVRQAIREEVAAVEAAKIRADEEKKKKEREEQVRLLQESADKDAEMNEASTATSENEDLKDDLSLADLSSKKTANSQATENNNTPSKAKVKAESKVRSKAKSDKSRAKLSSDTNKDSEKNDNNDASLQSAGVASDGESSPETPLTKASKSKKAKASKLANDTSKNANGETKSTPKKSKKKTSKAQQEANSTTAEGKEKLSGDSTETGNSTNKEASTEDTKANATASAPNKKKKTVETLQQQVIKEIARKEIPRVYKIIQQNQYNRSTNARKTSQLCGREARRWQFRTIKNNKDMQTKAKRAMRETMVFWKRNERVERDLRKKAEREALDRAKKEEELRESRRQARKLDFLITQTELYSHFVGRKMDREQDLPSATNTASVSEINFDSDEEEDIRRLAVESAQEAVQKAREHSQLFDANRQQSPNNSSSDMNEGEMNFQNPTLVNAFEVKQPKMLMCKLKEYQLKGLNWLANLYEQGINGILADEMGLGKTVQSISVMAYLAETHNIWGPFLVIAPASTLHNWQQEITRFVPKLKCIPYWGSTKDRKILRKFWCRKNMTYDENSPFHVVVTSYQLVVLDAQYFQSVKWQYMILDEAQAIKSSSSSRWKSLLAFKCRNRLLLTGTPIQNTMQELWALLHFIMPSLFDSHNEFSEWFSKDIESHAQSNTQLNEQQLKRLHMILKPFMLRRVKKNVQSELGEKIEKEVYCDLTQRQKILYQALRRQISIAELLEKAILGGDDTVASIMNLVMQFRKVCNHPDLFEREDVRSPLSLATWSKSIYINREGNFLDVPYNTRNFITFSIPRLLYEQGGILSVPGLNTSRGFETKYLYNLMNIWNPEYTNDSIKSNPEGSPFSWLRFVDESPQTLFQTFQNPVVHYLDEAEASSSLKEEQLCRQEFCYGKDYSNVRKMLLLPKSITKVDVLGSDFKEDSPFYHLTHVLEESDSQLDLTLLDSVLVQRASAPPIDIYCPGSRQFTVLQSRFQRDHLWSHYLYQPLKGEEDLIINNQAVSKLPIPRKPLLPSFGIAKGSYSNVRIPSMLRFIADSGKLSKLDKLLVELKANDHRVLIYFQMTRMIDLMEEYLTFRQYKYLRLDGSSKISQRRDMVTEWQTRPELFVFLLSTRAGGLGINLTAADTVIFYDSDWNPSIDSQAMDRAHRIGQQKQVTVYRFITRGTIEERIVIRAKEKEEVQKVVISGGETRPTKQMDLKGNSREMVSWLLEE
What is the function of this protein?
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
What are the official names of this protein?
Chromatin-remodeling ATPase INO80.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MLEX_CHICK
Sequence: MPLKKPDPKKDAAKAAAAPEVPKEFTFDPKSVKIEFAAEQIEEFKEAFSLFDRTPTGAMQITYAQCGDVLRALGHNPTNAEVLKVLGKPKPEDLNTKMLDFETFLPILQHFTRNREQGTFEDFVEGLRVFDKEGNGLVMGAELRHVLVTLGEKMTESEVEQLMAGLEDANGCINYEAFVKHIMSG
What are the official names of this protein?
Myosin light chain, embryonic, L23.