PharMolix/UniProtQA huggingface dataset:
Protein: MNHA2_STAAW
Sequence: MSLVYLLIAILVIMAMILLMSKRRALAKYAGYIALVAPVISSIYFLIQIPSVAKLQYLSTSIPWIKTLDINLDLRLDGLSLMFSLIISLIGIAVFFYATQYLSSRKDNLPRFYFYLTLFMFSMIGIVLSDNTILMYIFWELTSVSSFLLISYWYNNGDSQFGAMQSFMITVFGGLALLVGFIMLYIMTGTNNITEILGQADHIKNHGLFIPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLLRFTPLLGLSNMYVYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAMVGIGGGYAQHQQDAIASIYVFVLFGALFHLMNHAIFKCALFMGVGILDHEAGSRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLISMIAIVFVGVIASVFTFTYALYMVKEVFWTKYDSKVFTKKNIHEPWLFSLPSLILMVLVPVIFFVPNIFGKGIIVLALRAVSGGNHQIDQLAPHVSQWHGFNIPLLLTIIIILLGSVLAIKVDWKKVFTGKIRQISVSKSYEMVYRHFEKFATKRFKRVMQDRLNQYIIMTLGIFMIIIGYGYIRIGLPKVHQLHVSEFGALEIILAIVTVTIGISLIFIRQRLTMVILNGVIGFVVTLFFIAMKAPDLALTQLVVETITTILFIVSFSRLPNVPRSNANKKREIIKISVSLLMALIVVSLIFITQQTDGLSSISDFYLKADKLTGGKNIVNAILGDFRALDTLFEGLVLIITGLGIYTLLNYQDRRGQDERE
What are the official names of this protein?
Putative antiporter subunit mnhA2, Mrp complex subunit A2, Putative NADH-ubiquinone oxidoreductase subunit mnhA2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BR2A_SYLGU
Sequence: GFSSLFKAGAKYLLKSVGKAGAQQLACKAANNCA
What is the function of this protein?
Antimicrobial peptide.  Active against the Gram-positive bacteria S. aureus FDA209P (MIC=14. 9 ug/ml) and B. subtilis ATCC 6633 (MIC>64 ug/ml), but not active against the Gram-negative bacterium E. coli or the fungus C. albicans.
What are the official names of this protein?
Brevinin-2GHa, AMP-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: HUTG_STAAR
Sequence: MYKQGEPNLWTGRLDSETDPKKFRHFQTVTFEDLSKLEKSSTPSGVGILGYAVDKGVALNKGRIGAKEGPDAIKQAFAGLPDLNQCETLVDYGNVYHDHEELIDTQKEFATLAAKSIVNHRQTFLLGGGHDIAYAQYLATRKVYPTQSIGVINIDAHFDTRAEQQSTSGTSFRQILEEDENTGYLVLGIAQGGNTQSLFDYAKEKKIDYVFADELLSHVSPTIKDMIERFIHEHDVIMFTICMDVIDSAFAPGVSAPAVLGLYPHTVLELAKRIIPSDKVSSVSIAEMNPTYDADNRTAKLVANLVHHFLK
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: TIG_STRR6
Sequence: MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGFRKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQDWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAAENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVTFPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKELAAAKEETYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDMYFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYNMEVAQVQNLLSADMLKHDITIKKAVELITSTATVK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PNCB_ECOL6
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLENKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLHQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: NUOD_RHOPA
Sequence: MADAAAPDAASVRNFTINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLIEQKTYLQAIPYFDRLDYVAPMNQEHAFCLAVEKLLGIAVPRRAQLIRVLYAEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMMFYERASGSRMHAAYFRVGGVHQDLPPKLVDDIDAWCDAFPAVVNDLDRLLSDNRIFKQRNVDIGVVTLDQAWSWGFSGVMVRGSGAAWDLRKSQPYECYAELDFEVPIGKNGDCYDRYHIRMEEMRQSVRIMKQCIAKLRAPHGQGPVVVDDHKIFPPRRGEMKRSMEALIHHFKLYTEGFHVPAGEVYVAVEAPKGEFGVYLVSDGSNKPYKCKIRAPGFAHLQAMDFLSRGHLLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DJ12_CAEEL
Sequence: MAAQKSALILLPPEDAEEIEVIVTGDVLVRGGLQVLYAGSSTEPVKCAKGARIVPDVALKDVKNKTFDIIIIPGGPGCSKLAECPVIGELLKTQVKSGGLIGAICAGPTVLLAHGIVAERVTCHYTVKDKMTEGGYKYLDDNVVISDRVITSKGPGTAFEFALKIVETLEGPEKTNSLLKPLCLAK
What is the function of this protein?
Catalyzes the conversion of methylglyoxal (MG) or glyoxal (GO) to D-lactate or glycolic acid respectively in a single glutathione (GSH)-independent step.  May play a role in detoxifying endogenously produced glyoxals.  Involved in protection against glyoxal-induced cell death.  Protects dopaminergic neurons from glyoxal-dependent neuronal degeneration.
What are the official names of this protein?
Glutathione-independent glyoxalase DJR-1.2, Protein DJ-1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. DJ-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMC_XANCP
Sequence: MSEAPAVMSAEQLLREAVIRIARSDAEPLLLHALGRDRAWLFAHGRDPVPAEQAQRFGALVERRHQGEPVAYLTGSRGFWTLDLAVSTATLIPRADTETLVELALERLELTAGVRVVDLGTGSGAIALAIASERPQAQLIATDASADALAIARHNAHAHGLHNVECRLGHWLQPLAGERFDLIASNPPYIAAADPHLQQGDLRYEPASALASGSDGLDDIRLIVADTPAHLLAGGWLLLEHGWDQGEAVAALLIARGFAAVATHQDLEQRDRVTLGQWPHAAG
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: VL1_FPVL
Sequence: EPVPETVPIASREQIEKNNSAYMACPSGSVITSDTNLFNRSYWTNNGILWNENLFVTVLDNSRNVIMKISSLAEGAQENNATVYDWKNYYECVRHVEEYGISAIVRLCRV
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and about 55 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  The capsid encapsulates the genomic DNA, but does not bind DNA.  Essential for the initial attachment to the host cell (By similarity).
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion.
Protein: SYN1L_HUMAN
Sequence: MESLSELQNPLLPRSPAHLHGPYPYPETPPSWSCQEKLYSYLLGGAGPAGAHQLLDPGSLQLAVEAWYRPSCLLGRDKVKEPRAGSCETSFTEDREPQEGPPEQPTGPGQAAENVTIQTVSYGVQEELRDQEDDQEEEESDATSTESESEDNFLTLPPRDHLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLATLAIAVGAGLYVAVVVALAAYMSQNGHG
What are the official names of this protein?
Synapse differentiation-inducing gene protein 1-like, Capucin, Dispanin subfamily C member 1, DSPC1, Transmembrane protein 90A.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network.
Protein: MRAY_MICLC
Sequence: MIGLLIGGVLGLVLSAAGTPLFIRFLVKRGYGQFVRDDGPTTHKTKRGTPTMGGAVIIGSLVLAYLITHGLLAVLGVDFGGPTASGLILLLLTVGMAFVGFVDDFTKITKQRSLGLTPRGKIILQALIGTAFAVLALNFPDERGLTPASTAISFARDIPWLDLAFAGPAIGVILFVIWSNLITTATTNAVNLTDGLDGLATGATAMITGAYVLISLFQSSQSCALEGTRGCYEVRDPMDLALLAAILTGSLLGFLWWNTSPAKIFMGDTGSLGLGGALAGFAIFTRTEILVAVLAGLMVAITLSVIIQVGWFKVSGGKRVFLMAPLQHHFELKGWAEVTVVVRFWLLSLMCVTVGLAIFYGDWLIRQGGLAGVTP
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAPA5_CARPA
Sequence: GPLAVAINAAYMQTYIGGVSCPYICSRRLNHGVLLVGYGSAGYAPIRLKEKPYWVIKNSWGENWGENGYYKICRGRNICGVDSMVSTVAAVHTTSQ
What are the official names of this protein?
Cysteine proteinase, Clone PLBPC13.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: CLSA_PSEPG
Sequence: MDYHSPYFFGYLLGLIHLLGIVAALHAVFTVRTAQGAIAWAMPLFFIPYLTLIPYLVFGARSFYAYIKARRQANHEMHVAMANLNWRPWVEEALTARESESYAALRAMPKLSRMPCLANNQVKLLINGQATFDAIFAAIEKARDVVLVQFFIIHDDTLGKALQQLLLRKAAEGVQVFVLYDRVGSHALPASYSQVLRDGGVQIHAFATRRGWFNRFQVNFRNHRKIVVVDGLVGFIGGHNVGDEYLGKHPQLSPWRDTHVQISGPVLACLQESFAEDWYWATRQLPPLILPDAYPDNGVLCQALASGPADPQETCSLFFLEAIHSATRRVWITSPYFIPDEAVFAALRLAVLRGVDVRVLIPSRPDHRIVYAASSLFAFEAVRAGVRVFRYQPGFLHQKVVLVDDDVSAIGSANLDNRSFRLNFEITLLTVDRSFADQVEHMLNDDFEQAREITAEDSRDTHRLQQLGMRIARLISPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LAT_HUMAN
Sequence: MEEAILVPCVLGLLLLPILAMLMALCVHCHRLPGSYDSTSSDSLYPRGIQFKRPHTVAPWPPAYPPVTSYPPLSQPDLLPIPRSPQPLGGSHRTPSSRRDSDGANSVASYENEGASGIRGAQAGWGVWGPSWTRLTPVSLPPEPACEDADEDEDDYHNPGYLVVLPDSTPATSTAAPSAPALSTPGIRDSAFSMESIDDYVNVPESGESAEASLDGSREYVNVSQELHPGAAKTEPAALSSQEAEEVEEEGAPDYENLQELN
What is the function of this protein?
Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development (PubMed:25907557, PubMed:23514740).  Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.  Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
What are the official names of this protein?
Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts.
Protein: HGXR_TOXGO
Sequence: MASKPIEDYGKGKGRIEPMYIPDNTFYNADDFLVPPHCKPYIDKILLPGGLVKDRVEKLAYDIHRTYFGEELHIICILKGSRGFFNLLIDYLATIQKYSGRESSVPPFFEHYVRLKSYQNDNSTGQLTVLSDDLSIFRDKHVLIVEDIVDTGFTLTEFGERLKAVGPKSMRIATLVEKRTDRSNSLKGDFVGFSIEDVWIVGCCYDFNEMFRDFDHVAVLSDAARKKFEK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to the N(9) of hypoxanthine, guanine or xanthine, leading to IMP, GMP and XMP, respectively.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway.
What are the official names of this protein?
Hypoxanthine-guanine-xanthine phosphoribosyltransferase, HGPRT, HGXPRT, HGXPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_ECOHS
Sequence: MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLAANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTFLGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVSA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: NUCS_CORDI
Sequence: MRLVIARCSVDYIGRLEAHLPMADRLLMVKADGSVSIHADDRAYKPLNWMTPPCTLTETTHEESETGESIPLWIVENKKGEQLRITIEALHSDMYYDLGEDPGLQKDGVEAHLQELLAEHIETLGDGYSLVRREYPTPIGPVDILCRDDKGGSVAVEIKRRGGIDGVEQLSRYLELLNRDDLLAPVAGVFAAQHIKPQARTLAEDRGIRCVTLDYDSLRGIESTELRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_CAMJE
Sequence: MATRHQVRQSVISLLYAFELNSQNNVFVDEILDEKKIRNEQKNFTLNLYNGILDNLNNIDETLNSFLNDNQITALGHVERAILRLGAYELLFTDTPSAIVINEAIELAKELANDNSPKFINGVLDALIKAKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: MNMC_VIBVY
Sequence: MTSITHAELGWNEVGTPVSDQFDDVYFSNVNGLEETRYVFLKQNLIPERWQEFDRRRFVIGETGFGTGLNFLAVWQAFNDFRRANPDATLKELHFISFEKFPLSKQDLIKAHQAWPELAELAEKLHRHYPPAVPECHRIVLDNGAVTLDLWLGDIKDCLPSVPYGEEGIIDTWFLDGFAPSKNPEMWNQDLFNGMAKLARSECRVATFTSAGFVRRGLIEAGFAMKKVKGFGTKREMIAGCMETRQPQSRHAPYFNRTSASHLDSIAIIGGGIASAALAKALVQRGQKVTLYCKHAQAAEGASGNRQGAVYPLLNGSHDGVSRVFAPAFLFTRQFVEQAAQALTFDHDWCGVTQLMWDEKSTNKLDKMLSGNFAPELIQKLSAEETAAKIGLPIDMASVHYPLGGWLCPAELTQALFAQLDTLDNFTAKFEQSVEQLIWDERSQQWQVHTQGQHDTYSAVVIANGHEFQTFSQTADIPLGQVKGQVSHAPATETLSKLKSVLCYDGYMTPVNPNNQHLCIGASYDRRHLDTEFDVNAQQENAEKLTQCVPNQAWAKEVDTSGNLSRQGIRCVSRDHLPFVGNVGDFSAIKRQYADLPHTQAEEIEVISQFPNLFCLLGLGSRGLSSAPLMAELLASQICNDPLPLPVDVLEELHPSRMWVRKLRKGKAITEL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLEC_DROME
Sequence: MLCPPMALGPFLAAPVPRPPPSASEKKRICRNLFNNAPGDSNIDQLLAQEQHTQRLYVKERYGYDIQLESNRDADANTDADADTDAHCQVLRGMRYPTSRTISSTDADECNPKAVSQAPRGMALTPAQISASAKLILQKCPESDRKKSNGSADLANCTRHGQKPYARQPQGLKGMYNVRKTVNGISKPNVKNGYNNNNNSSSSNNNSNMNINNKIVDNGTSELADQKQ
What is the function of this protein?
Has a role in intercellular carbohydrate-mediated cell adhesion.
What are the official names of this protein?
Gliolectin.
What are the subcellular locations of this protein?
Membrane; Single- pass type II membrane protein.
Protein: TOP1_RICCN
Sequence: MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGESISWHVAEVIKEKNQVKSDDFFKRVAFNEITKKAIIHAVENPRKLDTNLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKNAKDLTKKLKSHKFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKSYGDKYLPTSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLDKDYYKLYELIWKRTIACQMENVIMDLVVANLASENKEYLAKANGSTIAFDGFYKVYRESMDDEAEEENKMLPPLKEQEPLKTKAVIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVALEKKRFIPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDAIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFGENKESKICPSCNTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENEGEPAAMPNENKVLGTDKDGVEIYLKKGPYGPYIQLGKQEGKVKPKRSPVPASLNQNDITLDIALKLLSLPLKIGIHKDSDEEIMIGYGKFGPYIKYMGQFISVQKKYDFLNLSLDDAMKLIEENKAKLEKKQA
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: TRUA_VIBA3
Sequence: MKIALGIEYNGTHYFGWQRQRDVKSVQEELEKALSVVANHPVEVMCAGRTDAGVHGTGQVVHFETNVDRKMVAWTMGANANMPKDIAVRWATEVNEDFHARFSATARRYRYIIFNHALRPGILNSGVSHYHGHLDEKKMHEAGQYLLGENDFTSFRATHCQSRSPWRNMIHLNVTRHGHYIVIDIKANAFVHHMVRNITGSLIAVGKGDQKPEWIQWLLEAKDRKVAGATAKAEGLYLVDVDYPEHFGLPREPIGPLFLPDNLN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RR19_BIGNA
Sequence: MARSFKKIPFVSNKLLKKVKLFNRKKVILTWSRASTIVPVMIGNVIAVYNGNKHIPIFVTDGMIGHKFGEFSATRTFKSHKS
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RBL_PROM1
Sequence: MAKKYDAGVKEYRDTYFTPDYVPLDTDLLACFKCTGQEGVPKEEVAAAVAAESSTGTWSTVWSELLVDLEFYKGRCYRIEDVPGDKDAFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPMAFIKTCGGPPSGIVVERDRLNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDLTKDDENINSQPFQRWRERFEFVAEAVKLAQQETGEVKGHYLNCTATTPEEMYKRAEFAKELDMPIIMHDYITGGFTANTGLANWCRENGMLLHIHRAMHAVIDRHPQHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDNLRESFVPEDRTRGNFFDQDWGSMPGVFAVASGGIHVWHMPALLAIFGDDSCLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILLEAAKHSPELAIALETWKEIKFEFDTVDKLDVQ
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: Y267_AQUAE
Sequence: MFYVSKVTPFFFALALLNLLISLFIRLSQDTSLFFVSLVFGFVGLTLMGAMYQIIPNSQNRKLSIPKVSYLVFFLILVSFYEFYTGNTESGSLFLFLGSLIFFFHLLLNVKNFYPLTVRFLLASMIYLVLSALFLYLHFKGFLPVQLSVHTLTVGSMLNAIYGVELAWIPMLIMETLNIRKGEKLFTAKQVSTLALLLAFWSMNYKLIALAGLLEFGVALYFLYLNYELFKRKRMPTPPPNVVKIFLFALLFLPLGMLLGIFSASHAQALPFSLRLHLDLILYGFGAFTIFGGMLHLLPRIVWNWKVQEKENPGFTMGDLVNERELQTFLEYSALLYALFLAVDSLFSPLHVISTVVYLVIMALFLKEIHKAFLYIFK
What are the official names of this protein?
Uncharacterized protein aq_267.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: G6PI_ERWT9
Sequence: MKNINPTQTAAWQALQQHFEQMKEVHIADLFANDANRFAAFSATFDDRMLVDYSKNRITSETLEKLQALAKETDLQSAIKSMFSGEKINRTEDRAVLHVALRNRSNTPIVVDGKDVMPEVNAVLAKMKAFSERIISGEWKGFTGKAITDVVNIGIGGSDLGPFMVTEALRPYKNHLKMHFVSNVDGTHIAETLKMLSPETTLFLVASKTFTTQETMTNAHSAREWFLTSGQQQDVAKHFAALSTNGEAVSEFGIDTDNMFEFWDWVGGRYSLWSAIGLSIALSIGYENFEKLLSGAHAMDRHFADTPEEKNLPILLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRAGNPVSYQTGPIIWGEPGTNGQHAFYQLIHQGTKLVPCDFIAPAVSHNQLGDHHSKLLSNFFAQTEALAFGKSREVVEKEFADAGKDAQSVEHIVPFKVFEGNRPTNSILLRDITPYSLGALIAMYEHKIFTQGAILNIFTFDQWGVELGKQLASRILPELADAAEVSSHDGSTNGLINLYKSWR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAEQ_SHIFL
Sequence: MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRLLAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEVALFTYNSRAAQIWWQQNQSKCVQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGVIWLSDDKNNLEVNLTAWQQPS
What are the official names of this protein?
Uncharacterized protein YaeQ.
Protein: KLRI1_MOUSE
Sequence: MLHSKRREYTANNQDVTYTELKTCKSPWKHRIPTVKQSPVVLCEEQLKYGELTFHRTPQPQPRKQAMGRKRQGPKSTVWRVVTGMLGALCVVLMTTTGILLPKLFSSQEEQCRKTSLHPLRCPKDDASCDLCSSDWIAFGNNFYCVFKENTKTWAESQSACEELNSHLVIIDSKAEVENLLLFEMDGWILHKMDGTNSSWLWRNDIKIQNTLTNDSEKKNHSCHYLRGNLFMPDECSAKKSYICEFNI
What is the function of this protein?
Lectin-like receptor for natural killer (NK) cells.  Heterodimer formation with KLRE1 mediates inhibition of NK cell cytolytic activity.
What are the official names of this protein?
Killer cell lectin-like receptor subfamily I member 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.