PharMolix/UniProtQA huggingface dataset:
Protein: PRIS_METPE
Sequence: MRPATLEFIKQQFTGYYQRVYPVTPDALLQREWGFIFFDAGREVRMRRHLAFGERQELTEYLKTMVPAHVFYSSAYYESPGAPTMAEKGWSGADLIFDLDADHIMHGSYQAMLARVKEEVQKLLAVLTDELGFSEKYCEVVFSGGRGYHIHVNDLAVRSWGSAERREVVNYVCGIGLDPGLLIRAGTDLSTGWPRRYLGALDGYLAWLKVKNQKDALLHLSSIKGVSRSSAAGLLKSLDQVRATIGGDHPEKVLGDRVLRAVTTNDNPDWKKRLQETGVQADEPVTTDIKRLIRMPTSLHGGSGLRVVPLTISEVQEFDPLIDAVVFGDRDVQVTAEKTLTVSLLGNTYEVSAGTQTVPEAVAVFLCCRGLAEIAEGR
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: TYSY_STRPJ
Sequence: MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAFSEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDTGTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMFDVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNLHIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_GRAFK
Sequence: MKSITINGSKRESVGKKATKALRNAGQVPCVLYGVEGDPLHFAAEEISFKNLVYTPDVHTVKIKLKSGESYDAILQDIQFHPLTDAILHIDFYQIFGEKPITMEIPIHTEGVARGVKNGGVLRYNLRRLKVRGLPADLPDYIVANVSKLKIGQKLYVTGVDSKDFVIQHPDNTVICQVRTSRNLVELEDEDEDEDEVAADEVPATEVDDQAAVKEGEGKE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ATPL_MESHJ
Sequence: MNSIVNFSQQLIQNFQEVSQRTAADSSNLKAFAYLGAGLAMIGVIGVGAGQGYAAGKACDAIARNPEAQKQVFRVLVIGTAISETSSIYALLVALILIFVG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADM_METMP
Sequence: MRAFLIGRWQPFHKGHLEIIKKISAEVDEIIVGIGSCQKSHTLTDPFTAGERMMMITKTLENYDINYYAIPIIDIDYNAVWVSSVESLTPPFTTIYTGNSLVRELFSERNYVVKKPELYNRTDYSGTKIRKKMLEGSAWEHLVPEEVVKVIEEIDGINRIRRLSEKDYDEE
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_SHEB8
Sequence: MLTIADVEFESRLFTGTGKFSNSQVMLEAITASKSQLVTVAMKRIDFKMGLDDLLTPLRQAGVRLLPNTSGARNAKEAVFAAELAREMLGTHWIKLEIHPDPKYLMPDAIETLEAARILCEKGFIVLPYVHADPVLCRRLEEVGCAAVMPLASPIGSNQGLVTESFLKIIIEQARVPVVIDAGIGAPSQAARAMELGADAVLVNTAIASSASPIVMAECFKEAVQCGRRAFEAGLGRVQTGAVHTSPLTGFLNQ
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_PSYA2
Sequence: MIMIKIGQGIDVHAFHNNGQQQQYVVLAGVPIEHTHSLLAHSDGDVVLHALADALLGALALGDIGQHFPDTDAANAGLDSRVLLRYVYGKVLAAGYMLGNADITVMCERPKLAVHNLAMRANIASDLQTDVSNISVKATTTEKLGFTGRQEGIMANAVVLLVPNTSGV
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: DER_AZOC5
Sequence: MSFTLAIVGRPNVGKSTLFNRLVGKRLALVDDRPGVTRDRREGDARLGDLAFRIVDTAGLEEADADSLEGRMRAQTETAIGDADALLFLIDARVGLTPTDRAFASLARRSGKPTILVANKSEGRGGEAGAMEAYELGLGAPVPLSAEHGEGLSDLYDAICEALPAQTAPQEEDEETEEAEANPNRPIKVAVIGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVEVTWNGRALEVFDTAGLRKRARIEDKLEKLSAADALRAMKFAEVVVVLMDATKPFEEQDLRIADLVVREGRALVLGYNKSDLVGPAAFSRLREEADHWLPQVKGVPIVPLSGLTGRGLDKLVEAIAATYAVWNTRIPTNPLNRYLQEATDSHPPPAVSGRRVKIRYMTQPKARPPSFVLFCSRPEALPESYLRYITNGLREAFSLPGVPIRLTLREKGNPYADKDK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: YOYG_BACSU
Sequence: MYGYSGYGYGFGCGTNTFVLIVVLFILLIIVGAAFIC
What are the official names of this protein?
Uncharacterized membrane protein YoyG.
What is the protein family that this protein belongs to?
Belongs to the SscA family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RECF_LACCB
Sequence: MKLDHLVLKNYRNYAAVDTTFSPEINVLIGANAQGKTNLLESIYVLALARSHRTNNDKELIRFGSEFARVSGQVSRQSGSHQLELIISHQGKRARIDRIEQPKLSQYLGHFNVILFAPEDLAIVKGSPAGRRRFIDMEFGQMSPKYLYNLSQYKTFLKQRNAYLKQLKYHQAKDLVYLDVLTDSLAAFGAELITARAKLLETMSDYAATIQQDITKGRESLHFSYQTQVDPSLRGDSEQVYTALGEMFAKQQAREIEQGTSLVGPQRDDVLFIVNDKDVANFGSQGQQRTTALAVKLAEIDLMKDQTGEYPVLLLDDVLSELDAARQTHLLKAIQTKVQTFLTTTSLEGIQKEIIATPAVFKVDEGTLARA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD_DECAR
Sequence: MPEEKIRLTQLSHGGGCGCKIAPAVLQKILAGTTGSIIPPQLLVGTETSDDAAVYQINAQQAIVATTDFFMPIVDNPRDFGRIAATNAISDVYAMGGTPLFALALVGMPVNVLPLETIGQILQGGEDVCRAAGIPIAGGHTIDSVEPIYGLVAIGLVNPEHLKRNSGAKSGDKLILGKQLGVGIYSAALKKDQLQAKDYEAMVETTTQLNTPGPVLACLDGVHAVTDVTGFGLAGHLLEVCKGSGLRATVNYQDLPVLPKAREFMQAGLMTGASGRNWASYGEGVRIADGLEGIAQTLLTDPQTSGGLLVSCSPETVTEVLSLFLQHGFPHVSVIGEMAEGEPGIDVI
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: ADEC_METMA
Sequence: MKKYMGIIVDAISRRQFKGEITVENGKIIRVEEKEHDNEQYILPGLVDAHVHIESSMTVPSVFARMAVAKGTVAVVSDPHEIANVMGEEGIEFMLEDSKKSPLKVYFGVPSCVPATPFESSGAVLDINAVDRLLAKDDLHYLSEMMNFPGVILEFPDVMAKLESARKHGKVIDGHAPGLRGADLQKYIGAGISTDHECFEYEEAREKIELGMKILIREGSSARNFETLYPLIDEYPDHVMLCTDDSHPDTLIYEGHIDKLIRRGQEKGLDIYNLIRTAVFNPVEHYGLNVGLLREGDPADFIIVDNLKSFNILSTFIDGECVYENGKVLFPLEKVPAKNVFNRNKISIDDVKLVPPAGAIQEQTTEKGIKKIRVIVANDGELVTGQELIVPKIENGNLVSDPERDILKMVVLSRYSDDPVRIGFIKNIGLEKGAIASSIAHDSHNIIAVGATDEDIVETVNRLIKNKGGIAVGTAENLLDLPLEVAGLMSTLEGEEVASRYHLLNEEARKLGTSLESPFMTLAFMSLLVIPELKLGDKGLFDVTKFEFVDLFADE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: SYR_HAEIN
Sequence: MNIQSILSDKIKQAMILAGADQSCDALIRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQKVLDNLQLSDIAEKLEIAGPGFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYSSPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEHASEMELQDLEAFYREAKKHYDEDEVFAEKARNYVVKLQSGDEYCRTMWKRLVDITMQQNQHNYARLNVTLTEKDVMGESLYNPMLPSIVKDLKKQGLAVENDGALVVYLDEFKNKDGDPMGVIVQKKDGGFLYTTTDIAAAKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPDSFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIERATVLINEKNTNLSNDEKEAVIEAVGIGAVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTDINSTALLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPILNAEDESIKLSRLKLALLTEKTLKQGLTLLGIKTVEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_PSEE4
Sequence: MEKLTLPAPAKLNLWLHITGRRADGYHELETVFQFLDHGDELSFSLREDGVIRLHSEIADVPHDSNLIVRAARKLQEQSGTRLGADIWLHKVLPMGGGIGGGSSDAATTLLALAHLWQLDWNEDRLAALGLALGADVPVFVRGHAAFAQGVGEQLTPVDPAEPWYVVLVPQVSVSTAEIFSHPELTRDSLPLKMRPVPEGNSRNDCQPAVEQRYPEVRNALISLGKFTEARMTGTGSCVFGAFPSKAEADRVLALLSETQTGFVAKGSNVSMLHRKLQSLIKKSSS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CH60_ALKMQ
Sequence: MAKEIRFGEKARRSLEAGVNKLADTVKVTLGPKGRNVVIDKKFGSPLITNDGVTIAREIELEDAYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLKNVAAGANPMIIKKGIHKAVDAAVAELKAVSKSIESKEAIAQVGAISAADEEIGQLIADAMDKVGKDGVITVEESKSMGTTLDVVEGMQFDRGYLSPYMVTDTEKMEAVFNDAYILVTDKKISNIQEILPILEQIVQQGKKLVIIAEDIEGEALATLVVNKLRGTFECVAVKAPGFGDRRKSMLDDIAVLTGATVISEELGYDLKTATVDMLGTARTVKVDKENTTIVEGAGNQQLIKDRVSQIKKQIEETTSDFDKEKLQERLAKLSGGVAVIQVGAATETELKERKLRIEDALNATRAAVEEGIVAGGGTALVNVIPAVEALLEGSQGDEKTGIQIIRRALEEPLRQIAENAGLEGSVIVNKVMSSDKGIGYDVLNNKYVNMIEAGIVDPTKVTRSALQNAASISAMLLTTESAVVDIASEEPGMPGGMGGMGGMGGGMPMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_RHOPT
Sequence: MSRIALYPGSFDPVTNGHLDVVRHAVALCDKLVVAIGIHPGKKPLFTTEERLAMVERVFGPVAKAAGCDFGCTTYDNLTVTAAEKVGATIMIRGLRDGTDLDYEMQIAGMNETMAPAIHTVFLPASVGVRPITATLVRQIAAMGGDVSAFVPAEVASALKSKFAAGSPA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGE_ECOL6
Sequence: MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASCGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYDAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXD9A_TAKRU
Sequence: MSRKRSKMSTSGPLSNCYVDAIMGQDSEDVYGARYIQAPHMVTPRPSSVGDNADFASCNFAPKSAVFSSSWSSVHPQGIYHPYVHHHHHHHQSHLPSADGRYVGVRSWMEPISNHVSFAGLHTSGRSYGTKPEVLPLKDAECDALEAESRPLSAGFVCAAAACPDRARKEHGASELPSHDEHKEEKQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLYNMYLTRDRRYEVARILSLTERQVKIWFQNRRMKMKKQNRERSGKEHI
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D9a.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: POPD2_MOUSE
Sequence: MSANGSSVAQLLWQPPVCRSWKPDVEGAVYHLANCFLLMGFMAGSGVYGCFYLFGILGPGYLCCVLWGWFDACGLDIVLWNVLLTVACLLQLAQLVYRVRVNTLPEEFNLLYRTLCLPLQVPLQVYKEIVHCCHEQVLTLATEQTYAVEGETPINRLSLLLSGRVRVSQDGQFLHYIFPYQFMDSPEWESLHPSEEGTFQVTLTAETECSYISWPRKNLYLLLNRERYISRLFSALLGYDISEKLYTLNDKLFAKFGLRFDIRLPSLYHVLSPSASDGEPESEKDDEEALEAAVSPAQARPICIVPTPPCSAPPATTNFPVPLPRARMPRMPRPDSGNLASRRPLQNSSQVMSRSQAPLAPIHTPEL
What is the function of this protein?
Important for the maintenance of cardiac function.  Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density.
What are the official names of this protein?
Popeye domain-containing protein 2, Popeye protein 2.
What is the protein family that this protein belongs to?
Belongs to the popeye family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane, sarcolemma.
Protein: TRPB_STRGG
Sequence: MSSDFFIPDPEGLIPSAEGYFGAYGGKFIPEALVAAVDEVAVEYDKAKSDPAFAAELNELMVNYTGRPSALTEVPRFAEHAGGARIFLKREDLNHTGSHKINNVLGQALLTKRMGKTRVIAETGAGQHGVATATACALFGLDCTIYMGEIDTERQALNVARMRMLGAEVVAVKSGSRTLKDAINEAFRDWVANVDRTHYLFGTVAGPHPFPAMVRDFHRVIGVEARRQILERAGRLPDAAVACVGGGSNAIGLFHAFIPDEGVRLVGCEPAGHGVETGEHAATLTAGEPGILHGSRSYVLQDDEGQITEPYSISAGLDYPGIGPEHSYLKDVGRGEYRAVTDDAAMQALRLLSRTEGIIPAIESAHALAGALDLGKELGKDGLILVNLSGRGDKDMDTAARYFGLYDADAAVEADADSDRAEIEGDAK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RK23_PROWI
Sequence: MMLNLLQYPVIKTPKATRLLENNQYSFDIDKKLTKPQIKKLVEEYFNIKVLAINTHRPPRKIKRSGSAPRSKRVIITVSANINLLG
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid.
Protein: MEPS_ECOLI
Sequence: MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVGSETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTFREQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHASTSSGVIISSMNEPYWKKRYNEARRVLSRS
What is the function of this protein?
A murein DD-endopeptidase with specificity for D-Ala-meso-diaminopimelic acid (mDAP) cross-links.  Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion.  Functionally redundant with MepM and MepH.  Also has weak LD-carboxypeptidase activity on L-mDAP-D-Ala peptide bonds.  Partially suppresses a prc disruption mutant.
What are the official names of this protein?
Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase, Lipoprotein Spr, Murein hydrolase MepS.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SYY1_BACAN
Sequence: MGILQDLEFRGLINQQTDAEGLEQLLEKESVKLYCGFDPTADSLHIGHMLPVLMLRRFQLAGHQPIALVGGGTGMIGDPSGKKAERTLNTKDTVAYYTESIKNQLSNFLEFENVENPATMANNYDWLGNLDVISFLRDIGKNFGLNYMLAKDTVASRLETGISFTEFSYMILQSYDFLNLYQHHNCRLQIGGSDQWGNITAGLELIRKSEEDAKAFGLTIPLVTKSDGTKFGKTEGGAIWLDPEKTTPYEFYQFWINTDDRDVVKYLKYFTFLSHEEILELEKQVAEAPEKRAAQKALGAEMTKLVHGEEALEQAIKISAALFSGSVAELTASEIEQGFKDVPSVERTAEDTVLIDLLVESKISPSKRQAREDVTNGAIYVNGERTQALDYVVTEKDRIEGKFTIIRRGKKKYFLIRY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase 1, Tyrosyl-tRNA synthetase 1, TyrRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIND1_ARATH
Sequence: MASLRLFSTNHQSLLLPSSLSQKTLISSPRFVNNPSRRSPIRSVLQFNRKPELAGETPRIVVITSGKGGVGKTTTTANVGLSLARYGFSVVAIDADLGLRNLDLLLGLENRVNYTCVEVINGDCRLDQALVRDKRWSNFELLCISKPRSKLPMGFGGKALEWLVDALKTRPEGSPDFIIIDCPAGIDAGFITAITPANEAVLVTTPDITALRDADRVTGLLECDGIRDIKMIVNRVRTDMIKGEDMMSVLDVQEMLGLSLLGVIPEDSEVIRSTNRGFPLVLNKPPTLAGLAFEQAAWRLVEQDSMKAVMVEEEPKKRGFFSFFGG
What is the function of this protein?
Together with ARC3 and MCD1, regulates FtsZ ring positioning in chloroplasts in an ARC6-dependent manner (PubMed:29967285, PubMed:28984364, PubMed:23936263).  Calcium-dependent ATPase required for the correct placement of the plastid division site.  Inhibits FtsZ filament and ring formation in the plastid.  Mediates inhibition of plastid division (PubMed:28984364).  In cooperation with MINE1, prevents FtsZ ring formation anywhere outside of the mid-plastids.
What are the official names of this protein?
Septum site-determining protein minD homolog, chloroplastic, AtMinD1, Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 11, Septum site-determining protein MinD1.
What is the protein family that this protein belongs to?
Belongs to the ParA family. MinD subfamily.
Protein: PDXA_ESCF3
Sequence: MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRESVTAGQLAVENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRVQGMKLKGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTI_ECOBW
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: X_PAVHV
Sequence: MDSYLTTPMPYHPVAVMQNLEEKMQYYLVKTYTSLGKLAYNYPVLTMLGLAMSYKLGPRKVLLTVLQGFMTLGIANWLSWE
What are the official names of this protein?
Uncharacterized protein X.
Protein: MAC1_MACFV
Sequence: GFGMALKLLKKVL
What is the function of this protein?
Antimicrobial peptide with activity against Gram-positive bacteria (B. subtilis, S. aureus and L. monocytogenes) and Gram-negative bacteria (E. coli and P. aeruginosa) (MIC=1. 3-35 uM) (PubMed:24616110, PubMed:29185466).  Also active against fungus C. albicans (MIC=6. 3 uM) (PubMed:24616110).  Has little hemolytic activity (PubMed:24616110, PubMed:29185466).  Acts by disrupting membranes and bacterial cell wall structures (PubMed:29185466).  Binds to peptidoglycan and lipopolysaccharide (LPS) (PubMed:29185466).  In the context of inflammation and cancer tests, is weakly cytotoxic to normal cells, induces calcium signaling but does not impact cAMP production (PubMed:36548715).  In addition, prevents LPS-induced nitric oxid (NO) synthesis but does not affect the IP3 signaling and pro-inflammatory activation of endothelial cells (PubMed:36548715).  Does not show significant antiproliferative activity on the breast cancer cell line MDA-MB-231 (PubMed:36548715).
What are the official names of this protein?
Macropin, MAC-1.
What is the protein family that this protein belongs to?
Belongs to the lasioglossin-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7L_SHEB8
Sequence: MQGTKNNIYTVSRLNGEVRQILEGQLGKIWLNGEISNFSSPSSGHWYLTLKDHSSQIRCAMFKGRNQTVSFKPINGQQVLVKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFDALKMKLAAEGLFAADTKRPLPKNIQRIGVITSPTGAAIRDVLHVLARRDPSIEVIIYPTQVQGETAAQSICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVDTTISDYVADIRAPTPSAGAELLSQDSDNKAQKLATALSRLQQSAKHYQLKQERRLSLLEHRLQRQDPKRTLQQFEQRFDEMQLRLESALSNRLHILSRRQQLLASRLEQQSPKHKLAIEGNRLSYLASRLQDALQDKLSQSEQRIKYAAHQLETVSPLATLSRGYSITTDIHNQVVDSTDKLTIGDSLQTRLRHGQVISTVTQIKPLE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.