PharMolix/UniProtQA huggingface dataset:
Protein: S61A1_MOUSE
Sequence: MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.  May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins.  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.  The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER.  Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC61 channel, contributing to the maintenance of cellular calcium homeostasis (By similarity).  Plays a critical role in nephrogenesis, specifically at pronephros stage (PubMed:27392076).
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha isoform 1, Sec61 alpha-1.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Protein: IRAD_ECO7I
Sequence: MMRQSLQAVLPKISGNKTSLLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIMLYHDDEPLTFDLVWDNGGWRSATLENVS
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraD.
What is the protein family that this protein belongs to?
Belongs to the GpW/Gp25 family. IraD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_PERMH
Sequence: MKVRSSVKKRCEKCRIIKRNGRIMVICENPRHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RDGC_DROME
Sequence: MDENAIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDDKDDLVEEFGDIVNAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLLRDKLAPGTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVAHMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSDLHRKEQQDENIRRRSTGRPSVAKTATDPVTLLADKISKNTLVVEHDIDPTDCESKVIDPKKS
What is the function of this protein?
Phosphatase required to prevent light-induced retinal degeneration.
What are the official names of this protein?
Serine/threonine-protein phosphatase rdgC, Retinal degeneration C protein.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family.
Protein: RRF_HAEDU
Sequence: MINEIKKDTQQRMEKSLEALKSHISKIRTGRAQPSLLDGIQVEYYGSATPLRQVANVVAEDARTLAVNVFDRSLISAVEKAILTSDLGLNPSSAGATIRVPLPALTEERRRDLIKIVKNEGEQGKIAIRNVRRDANDQIKALLKDKEISEDEERKAQDEIQKITDGYVKKVDEVLMAKEKELLDF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_STAEQ
Sequence: MALKKYKPITNGRRNMTTLDFAEITKTTPEKSLLQPLPKRAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGIIAKVDSIQYDPNRSANIALLVYADGEKRYIIAPKGLQVGQTVESGAEADIKVGNALPLQNIPVGTVIHNIELKPGKGGQLARSAGASSQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGVRPTVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SLEB_BACCR
Sequence: MRQKAIFKIAVLLAFIGLSLMVSSIQLKNVEAFSNQVIQRGASGEDVIELQSRLKYNGFYTGKVDGVFGWGTYWALRNFQEKFGLPVDGLAGAKTKQMLVKATKYDKSTANKGTTTNKGNSGGTAQENKPPQNKGTNVPNGYSQNDIQLMANAVYGESRGEPYLGQVAVAAVILNRVTSASFPNTVSGVIFEPRAFTAVADGQIYLTPNETAKKAVLDAINGWDPTGNALYYFNPDTATSKWIWTRPQIKKIGKHIFCK
What is the function of this protein?
Probable N-acetylmuramyl-L-alanine amidase.  Required for spore cortex hydrolysis during germination.  May form a complex with some hydrophobic spore component, leading to a stabilization of the enzyme in a spore-bound form (By similarity).
What are the official names of this protein?
Spore cortex-lytic enzyme, SCLE, Germination-specific amidase.
What is the protein family that this protein belongs to?
Belongs to the SleB family.
What are the subcellular locations of this protein?
Forespore. Note=Expressed in the forespore and then transported across the inner forespore membrane and deposited on the outside of the cortex.
Protein: LPTD_PSEMY
Sequence: MAVKHPAFRKKFPLLVTGSLLALQPAFSLQSFAAEQYDCQASPTGGWACAPKTATSALPPRPQHSRSAVSTTSGSATATATKQEPAPVLVTESKGRALASRSPDYSHLDWVPRDKLTAAQLAEAGPYCAGAYIEPLRPGMDDTTPLDESPMYVSAKASRYEQEKQIATLAGDVVLRQSGMQVEADEASLHQAENRGELVGNVRLRDKGTLVVGDRAELQLDNGEARIDNAEYVMHQAHVRGSALYAKREETAIIRLKDGTYTRCEPGDNAWHLKGNNVTLNPATGFGTATNVTLRVKDIPVFYTPYIYFPIDDRRQSGFLPPSLGTSSSNGFSLQTPYYFNLAPNYDATLYPTYMAKRGLLMEGEFRYLTESSEGQVGGAWLNDQEDERKLQSEYEDQRWMYSWQHKQGLNSRLLAEVDYTDISDPYYFQDLDTDLGIETQSYVNQRGTLTYRGDSYTARLNVHAYELANITDITPYDRLPQITLDGKLPFNPGGLDFTYGTEYVRFDRNLRSGFFVDKDGVTGRPQDLWYDARLTGLNRADGERLHLEPGVSLPLNWSWGFVKPQVKYLHTQYQVNLDGQGKADLATNDPENQWFGVDYKGSPNRGVGLFSLDSGLYFDRNTQLFGRETRQTLEPRAFYLYVPEEDQTDIPIFDTGEPTFSYASLWRENRFSGKDRIGDENKLSLGVTSRWIEPNGFERQRFSVGQAFYFEDRKVQLAGIDYRGRQDATSDVSPYALEYLYRFNRDWRFSSTFNWDPDQHATRSGSAMFHYQPEDNPNKIVNLGYRYRNDIVRYDRDSGTWTTNPDYGNPTLADGSPNPNYIKNYYKIDQHDFSVIWPLAPQWSLISRWQYDYGRNRTLEAFGGFEYDSCCWKLRLINRYWIDYDEVSLDPSRNDEPDRGIFLQIVLKGLGGVVGNKVETFLDQGIQGYREREDQAF
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: HTRA2_MOUSE
Sequence: MAALKAGRGANWSLRAWRALGGIFWRKPPLLAPDLRALLTSGTPDSQIWMTYGTPSLPAQVPEGFLASRADLTSRTPDLWARLNVGTSGSSDQEARRSPGSRRREWLAVAVGAGGAVVLLLWGWGRGLSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPISNGSGFVVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQNNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGTSGSQRRYIGVMMLTLTPSILIELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEKLAQNAEDVYEAVRTQSQLAVRIRRGSETLTLYVTPEVTE
What is the function of this protein?
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein.  Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism.  Cleaves THAP5 and promotes its degradation during apoptosis (By similarity).
What are the official names of this protein?
Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Mitochondrion membrane; Single-pass membrane protein. Note=Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with BID.
Protein: MNMC_CUPNH
Sequence: MPRALEPAEPILSAEGIPYSPRYDDVYHSTEGGLAQAAHVFLGGNGLPQAWAGQRQFVIVETGFGLGLNFLATWQAWRADPQRCGTLHFVSIEKHPFTREGLAQLHAGLDGLQPLAQALQAQWPLALPGLHRLAFDGGRVVLTLALGDIEQMLPRLAAGADAFYLDGFAPARNTEMWSPQVFRGLARLARPGARLATWAAAGFVRRGLKEVGFEVSRAPGFGGKWQMTVASFRPQWKARRHAPPLPAQWAERHAIVIGAGLAGCAVTERLAARGWRVTLFDGHDGPARQTSAHRAAAMHAHLSADDSLLSRLSRTGNQYALRAWAELAEAGHAVGWHGCGVLQIGEDEAEGEAQRAALAAMRLPEGFVRWMSAEEAAAAHHAGVPRGGLWFPQGGWVAPPDICSAQLAQAGAAVTARFGCRVAAIARVDGQWQALGQDGEVLASAPVLVLANAHEAQQLLPQQHWTMRRVRGQLTTLASAQVDALGGWPDCVVTGAGYLLPRTADGAGRVGSSYDADEGPLVEQPAVHAANLARLSGMLPRQADAVAAIDPATLSGYVGVRTVTHNRLPLVGQVPDEAAALAQAASLRGAHLRDLPRMPGLYAALAYGSRGLTWAALGAELLASQIEGEPLPLESDLADAMDPARLLLRALRHGHTG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_BACC0
Sequence: MKKEKAVVVFSGGQDSTTCLFWAIEQFAEVEAVTFNYNQRHKLEIDCAVEIAKELGIKHTVLDMSLLNQLAPNALTRTDMEITHEEGELPSTFVDGRNLLFLSFAAVLAKQVGARHIVTGVCETDFSGYPDCRDVFVKSLNVTLNLSMDYPFVIHTPLMWIDKAETWKLSDELGAFEFVREKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGASN
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: Y4623_BACAA
Sequence: MGTEFNGLFDEWAHTYDSFVQGEDIQYKEVFAHYEDILEDVVNKSFGNVLEFGVGTGNLTNKLLLAGRTVYGIEPSREMRMIAKEKLPKEFSITEGDFLSFEVPNSIDTIVSTYAFHHLTDDEKNVAIAKYSQLLNKGGKIVFADTIFADQDAYDKTVEAAKQRGFHQLANDLQTEYYTRIPVMQTIFENNGFHVTFTRLNHFVWVMEATKQ
What is the function of this protein?
Could be a S-adenosyl-L-methionine-dependent methyltransferase.
What are the official names of this protein?
Uncharacterized methyltransferase BAA_4623.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. YrrT family.
Protein: MTHSD_HUMAN
Sequence: MEPRAVGVSKQDIREQIWGYMESQNLADFPRPVHHRIPNFKGSYLACQNIKDLDVFARTQEVKVDPDKPLEGVRLLVLQSKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNYSVPIGLDSRVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTIVHDCQVVDIPEELVEEHDITVDYILTPTRVIATGCKRPKPMGITWFKISLEMMEKIPILRSLRAREQQAGKDVTLQGEHQHLPEPGCQQTVPLSVGRRPPDTPGPETNSMEAAPGSPPGEGAPLAADVYVGNLPGDARVSDLKRALRELGSVPLRLTWQGPRRRAFLHYPDSAAAQQAVSCLQGLRLGTDTLRVALARQQRDK
What are the official names of this protein?
Methenyltetrahydrofolate synthase domain-containing protein.
Protein: ISPG_MYCLE
Sequence: MNMRLGMPEAPAPGLAPRRITRQLMVGNVGVGSDHQISVQSMCITKTHDVNATLQQIAELTTAGCDIVRVACPRQEDADALAEIARHSKIPVIVDIHFQPKYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAAAAGIPIRIGVNAGSLDKRFMDKYGKATSEALVESALWEASLFEEHGFGNIKISVKHHDPVVMVAAYEQLAAQCDYPLHLGVTEAGPVFQGTVKSAVAFGALLSKGIGDTIRVSLSAPPVEEIKVGNQILESLNLRPRSHEIVSCPSCGRAQVDVYKLANEVSAGLDGLEVPLRIAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPEAQIVETLIEEAMRLVSEMGTEKGSDHCSETTRSGSPVVTVN
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RS4_MAIZE
Sequence: MARGLKKHLKRLNAPKHWMLDKLGGAFAPKPSSGPHKSRECLPLILIIRNRLKYALTYREVISILMQRHVLVDGKVRTDKTYPAGFMDVISIPKTNENYRLLYDTKGRFRLHPIRDEDAKFKLCKVRSVQFGQKGIPYLNTYDGRTIRYPDPLIKANDTIKIDLETNKIVDFIKFDVGNVVMVTGGRNTGRVGVIKNREKHKGSFETIHVEDSLGHQFATRMGNVFTIGKGNKPWVSLPKGKGIKLSIIEEQRKRDAAAQAAANA
What are the official names of this protein?
40S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_LEPIC
Sequence: MNFSKSLLLIAFGGAIGSIFRYLLQYWFGNVLGYSLPWGTLTANLLGSFLIGVVYAISDRFPLFDPQWKFLLASGFCGGFTTFSTFSYETFQMLKSGHYILFLGYICLSVVGGIGFAFAGVWMIKNF
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NIA_PHYIN
Sequence: MTRLRSAASTITNRSTPALALTASHAGSHPAVIVPIQPLLLTLERRPSCPHRVSYPEIEAYRGISSSLRSHNAIVRASDIMAQIDPRDVGTPDEWVPRHPELIRLTGRHPFNSEPPLKYASTFITPMALHYVRNHGPVPRLEWDTHTFSIDGLVKKPRTFGMNELVTTFEQETVTFPVLLVCAGNRRKEQNMIKKTIGFSWGAAGCSTAEWTGVPLHVLLTACGVDREKAQWVWFEGIEDLPHDKYGTCIRASTELDPECDVLVAWKANGELLGPDHGFPVRLIVPGHIGGRMVKWLERIHVSDHESSNHHHIMDNRVLPSHVTAETATAEGWWSKSPYAIMELNVNAVVILPNHDDLLALGEDTTFNDIETYTIKGYAYSGGGRRVIRVEVTLDDGASWQLARIIYHERPSKYGKMWCWVHYELAAPMSSLLCAREVCVRAWDSSMNLMPAFPTWNVMGMMNNPWYRVKIHHEQDTNSLRFEHPTQAGNQKGGWMTKERIMTNDVDSIKMLQVEPLDTSSAATPKPGLTADELSELPLIFADEVAKHNSKKSCWFICRDLVYDATPFLDEHPGGATSILLCGGTDCTDEFESIHSTKAWQMLKKYCIGRCSSTEDDTGTSDTSSDHEETDVALKGRTKVPIVLISREVVSHDARIFKFALPAKDLRLGLPIGNHVFLYAKINGKTAVRAYTPISSENDEDRGFVSFLIKVYFAGDNPVHPEGGLFSQYLDGLHLGQQIQIKGPLGHFTYYGDGNFSLETTNFHAYKFGFVAGGTGITPVYQVMRAILEDAKDQTKVALIYCVRSQRDLLLRKELETLQKLRPGQCRIFYTLSDMELLDRNDPIVRGWAYGKSRLNFAMVKNIIGSDAEDVCMCGPEGMIEYACKPALLKLNYDLKTQTTVF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADPH], NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: TIG_ECO45
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMN
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: GPMB_ECO5E
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: CYSD_SALPA
Sequence: MDQKRLTHLRQLETESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: CRTN_STAAM
Sequence: MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIERGV
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes three successive dehydrogenation reactions that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'-diaponeurosporene (the major deep-yellow pigment in staphylococci strains) as the end product.
What are the official names of this protein?
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming), Dehydrosqualene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtN subfamily.
Protein: RK5_GRATL
Sequence: MENTLKTLYNNKICKDLQKKFRYKNIHQIPKLVKITINRGLGEAANNKQVLEKSMNEIAAITGQKPKITKSKKAIAGFKIRENIAIGLVVTLRRDKMYDFLNKLINLALPRIRDFRGISYKTFDGRGNYNLGLKEQIIFPEIKYDNVDKIRGLDITIVTTAKNDEEGLTLLKEFGMPFM
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YIDC_SHESW
Sequence: MESQRNILLIGLLFVSFLLWQQWQADKAPKPVATESSLVANVASTHSADVPEADTGVPAAVAASKNLITVKTDQLDVQINPVGGDIVFAALVSHKMEQGKEQPFVLLEQTKDYTYIAQSGLIGRDGIDSSANGRAAFTTSATEFTLAEGQDTLEVPLTYVADNGVTYTKVFVFHRGKFNVDVDYKINNTSAAPLQVQMYGQIKQTIKPSESSMMMPTYRGGAFSTNDVRYEKYNFDDMAKSNLNQATLGGWAAMLQHYFVSAWVPPATDSNTIFSSVSAGGLANIGFRGAVYDIAPGASQEISSQFYVGPKDQAALSAISETLNLVVDYGFLWWLAVPIHWLLMFYQSFVGNWGVAIILITLTVRGLLFPLTKAQYTSMAKMRNLQPKLADLKERFGDDRQKMGQAMMELYKKEKVNPMGGCLPIILQMPIFIALYWVLLESFELRHAPFMLWIHDLSVQDPYYILPLLMGVSMFIMQKMQPIAPTMDPMQVKMMQWMPVIFTVFFLWFPSGLVLYWLVGNIVAIIQQKIIYAGLEKKGLK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OPSB_PSAFA
Sequence: MKSRPQEFQEDFYIPIPLDTNNITALSPFLVPQDHLGGSGIFMIMTVFMLFLFIGGTSINVLTIVCTVQYKKLRSHLNYILVNLAISNLLVSTVGSFTAFVSFLNRYFIFGPTACKIEGFVATLGGMVSLWSLSVVAFERWLVICKPVGNFSFKGTHAIIGCALTWFFALLASTPPLFGWSRYIPEGLQCSCGPDWYTTENKYNNESYVMFLFCFCFGFPFTVILFCYGQLLFTLKSAAKAQADSASTQKAEREVTKMVVVMVMGFLVCWLPYASFALWVVFNRGQSFDLRLGTIPSCFSKASTVYNPVIYVFMNKQFRSCMMKLIFCGKSPFGDDEEASSSSQVTQVSSVGPEK
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Blue-sensitive opsin, Blue cone photoreceptor pigment.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Protein: PRGI_SALTY
Sequence: MATPWSGYLDDVSAKFDTGVDNLQTQVTEALDKLAAKPSDPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNFR
What is the function of this protein?
Required for invasion of epithelial cells.
What are the official names of this protein?
Protein PrgI.
What is the protein family that this protein belongs to?
Belongs to the MxiH/PrgI/YscF family.
Protein: TXC6D_CUPSA
Sequence: FINTIKLLIEKYREWKNKQSS
What are the official names of this protein?
Cupiennin-6d, Cu-6d, Short cationic peptide-6d, SCP-6d.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 09 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXK_SALPC
Sequence: MIARIWSGESPLWRLLLPLSWLYGLVSGAIRLSYKLGFKRAWRAPVPVVVVGNLTAGGNGKTPVVIWLVEKLQQRGVRVGVVSRGYGGKAAAYPLLLTPETTTAEAGDEPVLIYQRTGAPVAVAPERAAAVKAILAAHNVQIIITDDGLQHYRLARDIEIVVIDGVRRFGNGWWLPAGPMRERASRLKTVDAAIVNGGVARAGEIPMQLAPGLAVNLRTGARCDVAQLSNIVAMAGIGHPPRFFATLEACGAHPQKCVPLADHQTLAPADVQALVGEGQTLVMTEKDAVKCRAFAEDNWWFLPVDARLSGEQPDKLLEHITSLVR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.