PharMolix/UniProtQA huggingface dataset:
Protein: GH38_ORYSJ
Sequence: MAVMTDVSTTGTALRTPAAGAVKEGDVEKLRFIDEMTTNVDAVQERVLGEILGRNAGTEYLTKCGLDGATDRAAFRAKVPVVSYDDLQPYIQRIANGDRSPILSTHPVSEFLTSSGTSAGERKLMPTIMDELDRRQLLYSLLMPVMNLYVPGLDKGKGLYFLFVKSETKTPGGLTARPVLTSYYKSDHFKNRPYDPYHNYTSPTAAILCADAFQSMYAQMVCGLCQRNDVLRLGAVFASGLLRAIRFLQLNWEQLADDIESGELTPRVTDPSVREAVAAILLPDPELAKLIRAECSKGDWAGIITRVWPNTKYLDVIVTGAMAQYIPTLEFYSGGLPMACTMYASSECYFGLNLRPMCDPSEVSYTIMPNMGYFEFLPVDETGAASGDATQLVDLARVEVGREYELVITTYAGLNRYRVGDVLRVTGFHNAAPQFRFVRRKNVLLSIESDKTDEAELQRAVERASALLRPHGASVVEYTSQACTKRIPGHYVIYWELLTKGAGATVVDADTLGRCCLEMEEALNTVYRQSRVADGSIGPLEIRVVRPGTFEELMDYAISRGASINQYKVPRCVTFPPIVELLDSRVVSSHFSPALPHWTPARRSE
What is the function of this protein?
Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excessive free auxin (PubMed:18192436).  Produces more IAA-Asp levels than IAA-Ala levels in vitro (PubMed:18192436).  May participate in the activation of disease resistance by preventing the accumulation of free IAA, which reduces the expression of a group of auxin-responsive genes encoding expansins that control cell wall loosening and expansion (PubMed:18192436).  Contributes to late events in stamen and carpel differentiation, and influences floret fertility (PubMed:22016342).
What are the official names of this protein?
Indole-3-acetic acid-amido synthetase GH3.8, Auxin-responsive GH3-like protein 8, OsGH3-8, OsMGH3.
What is the protein family that this protein belongs to?
Belongs to the IAA-amido conjugating enzyme family.
Protein: FOGD_ASPRC
Sequence: MSTKFALVTGCGQGGIGEALITEYARRGIHAIATVLPAEPSDHLARAGITFFPLDVTNEESVLELKARVQKLTGGRLDVLVNCAGIAYTMTAIDTDVAAVQRMFNVNVFGPMRMVHHFHDMIIKATGAIVNIGSIGGVVPYLYGSSYNATKAALQHWSNTLRVEMAPFDVRVITVISGEVATNILKNDAHRRLPEGSYYSPLAENFRQHVTRTPPRTTDRFQYAANVVAESLRSSPSAWFWYGSQSTLIRFLDMFCWRTVWDSLFWRMFDLGKLKEAHSSKAKKQV
What is the function of this protein?
Short-chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of flavoglaucin and congeners (including aspergin, dihydroauroglaucin and auroglaucin), prenylated salicylaldehyde derivatives carrying a saturated or an unsaturated C-7 side chain (PubMed:32134669).  The PKS fogA releases the carboxylic acid (8E,10E,12E)-3,5,7-trihydroxytetradeca-8,10,12-trienoic acid as its product, as well as derivatives with one and two double bonds (PubMed:32134669).  FogA is indeed able to reduce the initial triketide, thus being at least partially responsible for the differently saturated heptyl side chains of flavoglaucin congeners (PubMed:32134669).  The oxidoreductases fogB, fogC and fogD modify the nascent polyketide in fogA-bound form and, together, fogA, fogB, fogC and fogD are necessary for the formation of the aromatic core and the cyclized PKS products are released as salicyl alcohols (PubMed:32134669).  In particular, fogB is responsible for oxidation of a hydroxyl group or reduction of remaining double bond(s) at the C-7 residue whereas fogD is probably involved in the reductive release of the modified PKS products (PubMed:32134669).  The cytochrome P450 monooxygenase fogE is then responsible for the hydroxylation at C-3 of the benzene ring (PubMed:32134669).  The fogE products are substrates of the prenyltransferase fogH and the prenylated benzyl alcohols are subsequently oxidized by the fogF to produce the final aryl aldehydes flavoglaucin and congeners (PubMed:32134669).  The short-chain dehydrogenase fogG does not seem to be involved in the biosynthesis of the prenylated salicylaldehyde derivatives (PubMed:32134669).
What are the official names of this protein?
Short-chain dehydrogenase fogD, Flavoglaucin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: Y1210_LACCB
Sequence: MKQFYIVDSSMLPEVVGKVIAARALLQNGEVKQVSEAVKQVGISRGTYYKYKDYVFLPDPEMASRKAVISLMLHHDRGILSEVLTTMSQAQASIVTINQNIPIHNWASVVMSFDISALQGTLDDLVTKLGNIRGVSDVHLVSVE
What are the official names of this protein?
UPF0735 ACT domain-containing protein LCABL_12100.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: VP7_ROTHX
Sequence: MYGIEYTTILIFLISIILLNYILKSVTRIMDYIIYRSLLIYVALFALTRAQNYGLNLPITGSMDTVYANSTQEGIFLTSTLCLYYPTEASTQINDGEWKDSLSQMFLTKGWPTGSVYFKEYSNIVDFSVDPQLYCDYNLVLMKYDQNLELDMSELADLILNEWLCNPMDITLYYYQQSGESNKWISMGSSCTVKVCPLNTQTLGIGCQTTNVDSFEMVAENEKLAIVDVVDGINHKINFTTTTCTIRNCKKLGPRENVAVIQVGGSNVLDITADPTTNPQTERMMRVNWKKWWQVFYTIVDYINQIIQVMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: RS15_RHOOB
Sequence: MALTTEEKKQVLSEYGLHETDTGSPEAQVAMLTKRIVDLTEHLKMHKHDHHSRRGLLLLVGRRRRLLKYVQKVDIARYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RS9_TROW8
Sequence: MVPPQRAKNDTSSAPDSAAETRGPLVSSGSGLGRRKSATARVYLSPGEGVFVVNGRDINEYFTSKLHRQFACQPLKILDLLGSYDVKVTLHGGGASGQAGAVRLGIARALNTIDPENNRKPLKSAGFLTRDSRVKERKKAGLKKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: HEM3_SHEB5
Sequence: MSENRIRIATRKSPLAMWQAEFVKAELERIHPGIVVELLPMSTKGDVILDTPLAKVGGKGLFVKELEVAMLDDLADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELPLGATVGTSSLRRQCQIRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLSERIASFISAEESLPANGQGAVGIECRINDERVKALLAPLEHLETRYRVLAERAMNTRLEGGCQVPIGAFAEIDGDEMTLRGLVGNPDGSEIIEGVITGPKTEATQLGVALAEELLSKGAKTILDAVYAKA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: MKRN1_TAKRU
Sequence: MAEAAVASTVTLPVTGGWTKHVTCRYFMHGLCKEGDNCRYSHDLTSSKPAAMMCKFFQKGNCVFGERCRFEHCKPTKSEEVSNPQMLLLSSTPPPIDPECSESGPRLKTQDWANAAEFVPGQPYCGRAESVDVEISIPLIEELNGDATTDKEELRKQLCPYAAVGECRYGVNCAYLHGDVCDMCGLQVLHPTDSSQRSEHTKACIEAHEKDMEISFAIQRSKDMMCGVCMEVVFEKANPSERRFGILSNCSHCYCLKCIRKWRSAKQFESKIIKSCPECRITSNFVIPSEYWVEDKEDKQKLIQKYKDGMGRKPCRYFDEGRGICPFGANCFYKHAFPDGRLEEAQPQRRQTGSSSRNRNSRRTQLWDIIDERESTGSLDNDDEEMVTFELSEMLLMLLAAGNDEEVTDSEDEWDLFHEELDDFYEIYL
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase makorin-1, RING-type E3 ubiquitin transferase makorin-1.
Protein: PDRP1_ENTFA
Sequence: MKKEIIVYTISDSLGETSQKLLAAASAQYPDISFLNRYNFSFVTTEEELLEILKDALKDKALVVSTLVSKQLITAAKEFSERTGLLYLDLMAPFFELIQAKAGVDPIEEPGRRHQLDRAYFDKISAIEFAVKYDDGKNPQGFLDSDILLLGVSRTSKTPVSMYLANQGYRVSNLPLIPEVPLPPILEEMDPQKMIGLVCSPETLGQIRSSRLASLGLGNETSYTNVERIEQELAYAEEIFAKYGIPVIDVTAKSVEETAFLIKEKLDERN
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 1, PPDK regulatory protein 1.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: ACCA_CHLL3
Sequence: MATNVVLDFERPVVELEAKLNEMRECLRSSSREQAPVESDALSKEIETLEKKVDALRRSIYKNLTRWQKVQLARHPERPYTLDYIYMMTCDFVELAGDRHFSDDKAIVGGFARLEDRASGYSQPVMVIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMKLAEKFRKPVITLIDTPGAFPGIEAEERGQAEAIARNLYEMAKLTVPVIVVIIGEGASGGAIGLGVGDRILMAENSWYSVISPESCSSILWRSWNYKEQAAEALQLTAEDLLKQGIIDRIIPEPMGGAHTDPEAMASTLKGMLIEELKALMPVPEKELVNNRIEKFSAMGVWNDEG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_STRPI
Sequence: MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVDKPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGKYIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVRIPYSLVSKARLAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP6A_ARCFU
Sequence: MKEIERRCLRALIGIVQNIYDQMKAGQVPELHIATRTKYNIEFNEESEVWVYGDRKSVRSAKTVKGAYRILKMTYVIGFLKEQLNLNKSSTLRELYYISEGWGAAKFEEQPESDRLVEDLEILTNFQREHFHIRPEEDGATVIGPLRVREETRRGVREIHCQDDVGEGGYQIPVNVDKIEFVDHDAKFVIAIETGGMRDRLVENGFDEKYDAIIVHLKGQPARSTRRLLRRLNTELNLPVVVFTDGDPWSYRIFASVAYGSIKSAHLSEYLATPAAQFVGIRPTDIVKYDLPADKLTEEDIKALNAILTDPRFDSEFWKKEVNLQLEINKKSEQQALAKYGLDYVTDVYLPERLSELGVI
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit A, Type II DNA topoisomerase VI subunit A.
What is the protein family that this protein belongs to?
Belongs to the TOP6A family.
Protein: PIMT_BURM7
Sequence: MSGERAKRFPLALEDLKREPRKPEGRVAERQAAGDAARQRLTAAAAVPAAASPIVPERRAPHGGVFAAKPARAKQHAPAAPGAAKRAPQGGAKQGDRSAAPNVALSGALALTSERVRERMVERLRANGVADPRVLAAMSAVPRHMFVDPGLAAQAYEDAALPIGHQQTISKPSVVARMIELAAAGRALERVLEIGTGCGYQAAVLSRVARDVYSIERVRPLYERAKLNLRPLRVPNIRLHYGDGRVGLPAAAPFDAIVIAAAGLDVPRALLEQLAIGGRLVAPVGEQAGEQVLTLVERVAPAQWRESRLDRVFFVPLKSGVI
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_ECOL5
Sequence: MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KNG1_BOVIN
Sequence: MKLITILFLCSRLLPSLTQESSQEIDCNDQDVFKAVDAALTKYNSENKSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFQSNKTWQDCDYKDSAQAATGECTATVAKRGNMKFSVAIQTCLITPAEGPVVTAQYECLGCVHPISTKSPDLEPVLRYAIQYFNNNTSHSHLFDLKEVKRAQRQVVSGWNYEVNYSIAQTNCSKEEFSFLTPDCKSLSSGDTGECTDKAHVDVKLRISSFSQKCDLYPVKDFVQPPTRLCAGCPKPIPVDSPDLEEPLSHSIAKLNAEHDGAFYFKIDTVKKATVQVVAGLKYSIVFIARETTCSKGSNEELTKSCEINIHGQILHCDANVYVVPWEEKVYPTVNCQPLGQTSLMKRPPGFSPFRSVQVMKTEGSTTVSLPHSAMSPVQDEERDSGKEQGPTHGHGWDHGKQIKLHGLGLGHKHKHDQGHGHHGSHGLGHGHQKQHGLGHGHKHGHGHGKHKNKGKNNGKHYDWRTPYLASSYEDSTTSSAQTQEKTEETTLSSLAQPGVAITFPDFQDSDLIATVMPNTLPPHTESDDDWIPDIQTEPNSLAFKLISDFPETTSPKCPSRPWKPVNGVNPTVEMKESHDFDLVDALL
What is the function of this protein?
The active peptide bradykinin is a potent vasodilatator that is released from HMW-kininogen shows a variety of physiological effects: (A) influence in smooth muscle contraction, (B) induction of hypotension, (C) natriuresis and diuresis, (D) decrease in blood glucose level, (E) it is a mediator of inflammation and causes (E1) increase in vascular permeability, (E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e. g.  prostaglandins), (F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action).
What are the official names of this protein?
Kininogen-1, Kininogen I, Thiol proteinase inhibitor.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: HTPX_SHEPW
Sequence: MKRIFLLIATNMAILLVASIVMSILGVNTSTMSGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITNPRDNTERWLVETVARQAEQAGIKMPEVAIYQSQEFNAFATGPSKNNSLVAVSSGLLYGMNHDEIEAVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIINNFVASNDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREFKADEGGARLAGKEKMIAALDRLKQGPETGAMPASMSALGINGKKSMAELMMSHPPLDKRIAALRAS
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBIA_ACIAD
Sequence: MQPISWRERLQAYYYLCRFDKPIGTELVFWPTMWALWIASDGYPDLKMFVVMTLGVLFMRAAGCAINDFADRKVDGHVARTKQRPLATGIIRPIEAIWVFLALVAASAALLLFLPIETFYWSFGALFLAFIYPFMKRYTHLPQVFLGAAFSWAIPMAYTATGQAPDLTCWLLYFGNLAWTVAYDTQYAITDREYDLKIGVKSTAILFNRFDIPIISTLQLSSLLLIGMALYIENLLFPWGIIGLVVVAVDFIYQWTKTKNRDPQLCFWAFRHNRWVGLIIFLAILAAFRF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PPNP_PSEFS
Sequence: MFKVNEYFDGTVKSIAFGTAEGPATIGVMAPGEYEFGTAQREIMHVVSGALTVKLPDASTWETFAAGSQFNVPANSKFQLKVAVDTAYLCEYRG
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: TPIS_PANTR
Sequence: MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOND_SCHPO
Sequence: MITEFIKSFLLFFFLPFFLSMPMIFATLGEFTDDQTHHYSTLPSCDLLLIRGEVKENARCFLHNPKISHQHHSFWSLIEGCLEALQFGLLAILQGLFSQFAWEACSCTFACMLLTSERTEPSYPFSEITEVSRGGLHFVKLN
What are the official names of this protein?
Uncharacterized protein C1105.13c.
Protein: BIOB_PSEU2
Sequence: MSASTTATLRHDWTLAEVRALFVQPFNDLLFQAQTVHRAHFDANRVQVSTLLSIKTGACPEDCKYCPQSGHYNTGLEKEKLLEVQKVLEEAARAKAIGSTRFCMGAAWKHPSAKDMPYVLEMVKGVKAMGMETCMTLGRLDQEQTEALATAGLDYYNHNLDTSPEFYGSIITTRTYSERLQTLAYVRDAGMKICSGGILGMGESLDDRAGLLIQLANLPEHPESVPINMLVKVAGTPLENAEDVDPFDFIRMLAVARILMPKSHVRLSAGREAMNEQMQALAFFAGANSIFYGDKLLTTANPQADKDMLLFSRLGIKPEAGEGHADEVHQAAIEQALVEQQSSSMFYDAASA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ATPD_ACTP7
Sequence: MSELSTVARPYAKAAFDFALEQGQLDKWQEMLQFSAFVAENEQVAEYINSSLASGQISETFIKICGDQLDQYGQNFIRVMAENKRLAVLPMVFDTFVSLRAEHEAVKDVTIFSANELSQAQEDKIAKAMEKRLGQKVRLTNQIDNSLIAGVIIKYDDVVIDGSSRGQLNRLASALSL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUOC_RALPJ
Sequence: MTDKLATLKAALEKALGNRVQSLTESVGELTLVVKAADYLDAMRTLRDDASLKFEQLMDLCGVDYADYGDGAWNGPRFAAVSHLLSITHNWRVRVRVFAPDDDLPVVSSVTTIWNSADWFEREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPVQRRVVYQPVTIEPREITPRVIREDQYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VAT_CAMVP
Sequence: MSITGQPHVYKKDTIIRLKPLSLNSNNRSYVFSSSKGNIQNIINHLNNLNEIVGRSLLGIWRINSYFGLSKDPSESKSKNPSVFNTAKTIFKSGGVDYSSQLKEIKSLLEAQNTRIKNLENAIQSLDNKIQPEPLTKEEVKELKESINSIKEALKNIIG
What is the function of this protein?
This protein is involved in virus transmission.
What are the official names of this protein?
Aphid transmission protein, Atf, Protein 2.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae ORF II family.
Protein: TXD17_DANRE
Sequence: MSKYEEVAVHGYEEFCKAVSDRKGKEIFAYFSGDKDEHGKSWCPDCVKAEPVVRAELPHLPEGTVFIYCQVGDRPYWKDSNNDFKKTLKLTGVPTLLRYGTPQKLVEEECFKADLVRMMFTED
What is the function of this protein?
Disulfide reductase.  May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.  Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide (By similarity).
What are the official names of this protein?
Thioredoxin domain-containing protein 17, Thioredoxin-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD63_BOVIN
Sequence: MPTKKHRRKDPESPQEPSEKTKEQLVEGELRKLRQQFRKMVDSRKSFNFRSQQKITNQRKEIKTLQEEQDEITLLLNLIKSSRNLDLNEKNYLELRFLLQTKEDYEALIKSMKLLLAELDEKIVQMEKKIINQRQIFTKIQEANNPRKLQKQIHILETRLNLVTVHFDQMLTTNAKLRKEIEDLRHEKAAYDNVYQHLRRRLLTKKKTMNVAIEQSAQAYEQRLEAMARMAAMKDRQQKDISQYNLEIRELERVYDHETKLKSFLLIKLNDRLEFEEQSKKEEALKAKKYGKKSKGASFESYEVAHLRLLKLTKTGNLNQLIEEFLAKEEKNFARFTYVTELNNDMEMMHKKIERIQNEILRLRSQQKSSHDDSYSILRELEEKLKKTTEEADMYENDYREITKTLEYLKNSVENLFKKINCDATKILVQLGETGKVTDINLPQYFAIIEKKTNDLLVLESYKRLMEMEVAEAEVQPSFLNPFWGGSALLKPAEPIKVIPPVLGADPLSDKLDEVEQPLDHSSLRQMVLSHYATRESRNRDSMPEKGDELKSKKKVTV
What is the function of this protein?
Plays a role in spermiogenesis.  Involved in the elongation of flagella and the formation of sperm heads.
What are the official names of this protein?
Coiled-coil domain-containing protein 63.
Protein: UL23_HCMVM
Sequence: MSVIKDCFLNLLDRWRPPKTSRPWKPGQRVALVWPKDRCLVIRRRWRLVRDEGRDAQRLASYLCCPEPLRFVGSICTYNFLKHKGDHNVPSELYLGASGAMYLWTDHIYSDSLTFVAESITEFLNIGLRRCNFITVPEELPHTASLRALAGCMHIHAFAQWRATYRGRLMVMGDYSVIRVSTIRLYDWSEINDWRVMVGSNHVEPLGWLVSPYDVINLFVDDCMRVFAANNQHVCIVADSLMEFVTRGMTRCHENGIYYGTRSMRKLNKPTCPYGVDHQLFDDA
What is the function of this protein?
Plays a role in the inhibition of host innate immune response by disrupting the interaction between NMI and STAT1.  In turn, NMI-mediated transcription of interferon-gamma stimulated genes is inhibited.
What are the official names of this protein?
Tegument protein UL23.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm.
Protein: TRPB_ACTP2
Sequence: MSDTLLNPYFGEFGGMYVPEILVPVLKQLEEAFVAAQNDPLFQAEFTDLLKNYAGRPTALTLCRNLTKGSKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTRIIAETGAGQHGVATALACAMLDLPCVIYMGAKDVERQSPNVFRMRLMGAEVIPVQKGSCSLKDACCEAMRDWAANYETTHYLIGTAAGPHPFPTMVREFQKMIGEETKRQILEKENRLPDAVIAAVGGGSNAIGMFADFIEEKSVQLIGVEPAGKGIETGEHGAPLKHGTTGIYFGMKSPIMQTKDGQIEESYSISAGLDFPSVGPQHAYLNSIGRAEYVSITDQEALDAFQALAQHEGIIPALESSHALAYALKLIAQNPDKEQLLVVNLSGRGDKDIFTVDKILNGGN
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.