PharMolix/UniProtQA huggingface dataset:
Protein: LPXA_SYNAS
Sequence: MTVHPTAIVSPDARLAQGVEIGAYSVIGPGVTVGRNTFLGSHVVIERDTDIGEGCRISSFCSLGGDPQDLKYEGEKTRVIIGNYNVLREYVTVNRATSADIGVTIIGDHNLIMAYCHVAHNCKLGNHIVISNGSHLAGHIHVDDYAIISGMVGIHQFTRIGAHSIIGGASAVTQDVPPYVTAAGNHAKLYGLNLIGLERRGFSKETISALKEAYRIIFRSSSLRREDALEKVRQTVADTPEVRHFIDFIQTSERGVCH
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCS1_RAT
Sequence: MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV
What is the function of this protein?
Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner.  Directly regulates GRK1 (RHOK), but not GRK2 to GRK5.  Can substitute for calmodulin.  Stimulates PI4KB kinase activity.  Involved in long-term synaptic plasticity through its interaction with PICK1.  May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
What are the official names of this protein?
Neuronal calcium sensor 1, NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
Protein: ARGJ_LISMF
Sequence: MELVKGNIASPKGFYADGKHAGLKRKRNDIGWIYSEVPANAAAVYTMNQMQAAPIFVTKDSFQSNAKLQAIIVNSGNANACTGNQGMLDALAMRAQTAEKLDIPLDYVAVASTGIIGDMLPMDKINAGIEMLEKQTGNAADFEEAILTTDTFQKQISFQTEIGGRKVTMSGVAKGSGMIHPNMATMLAFITTDAAIPAELLQKLLKIKVDKTFNQITVDGDTSTNDMVVVMANGCAENPMLQEGTADFAKFADMFQAVMEHLAKSIARDGEGATKLIEVQVNGATKTEDARMIAKKIVSSSLVKTAAFGGDGNWGRIICAIGYSGGRFAPDNITIKIGGIEILNHSSQTIFNQQALDAYLEEEHIIIDVDLHIGLESGTAWGCDLSYEYVKINACYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_CLOBJ
Sequence: MNKSRIDKQNEVYNFIKLQIKEKGYPPSVREICKAVGLSSTSSVHFHLKRLEKEGLIKRDSSKTRAIEIVDPTSKKEVINVPIVGTITAGNPILAIENIEDVFPLPIDYVKNTKDLFMLKVSGESMIEAGILDGDLAIIEKTDSANNGDIVVALIDNEATLKRFFKESSYIRLQPENKSMKPIILENCKVLGRLVGIYRKY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: HSP22_MAIZE
Sequence: MDAVMFGLETPLMAALQHLLDVPDGDAGAGGDNKTGSGGSATRTYVRDARAMAATPADVKELPGAYAFVVDMPGLGTGDIRVQVEDERVLVVSGERRREEREDDAKYLRMERRMGKFMRKFVLPDNADVDKVAAVCRDGVLTVTVEKLPPPEPKKPKTIEVKVA
What are the official names of this protein?
17.8 kDa class II heat shock protein.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_DROMO
Sequence: MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGRVFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEAKTVDGYLLRVFCIGFTFKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDSIAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDISKLLELHGDGGGKTTEAVVSAEGAVIDRPEGYEPPVQEAV
What is the function of this protein?
Essential for oogenesis; required for late follicle cell development.
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_HYPNA
Sequence: MAARDTICALASGPPPSAIAIIRISGPAVAEIGKSLLASGLPEPKRAALTYIYDSDGALIDQGIALYANAPHSYTGEDTLELYLHGGPAVIDHALRGLTAIAGVRLAEPGEFTRRAFENGKLDLTEAEGVADIIEAETGAQKAQALRQLGGGLTEIYDGWREELTGTLALIEVMIDFPDEGDVPEDTARPILSRLEKIMSEIETALGDRGVGERIRDGFRVAIVGPPNAGKSSILNRLARREAAIVTDIAGTTRDVVEVRLVLGGQVVWIADTAGLRETEDVVEAEGVRRARRAAAEADLRIHVIDGTDPSPPPEQVETQDIIVFNKADQRPAILAPDGALPISVITGEGIDKLESWIAAFVSRRASSVEAPVITRARHREKLVAGLASLTAARDALVSDMGAELAGEDVRMALRQLSSVIGRVDVEDVLGAVFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2072_EMENI
Sequence: MSSRSGSADTFTQRSDSNLRPRRLISLDDVRDNNGRQPSSSGISTTGSSELPTLRSRGATPSPRPSRNVSPIPMGHPSRATQPRSDARPGNSLGGFTPNGKYQDPFTESSRAAVDFLDASWSSLQGIASSLLGSDTARPTSNGGPRSHARKPSRPDYLAKHRAVSTSTWGPSGPTTPEIGAGTQDERQAMVHAKKMEALLLADTDPSWNLNSRHKRRDSNDRTVQSRADTDQDEEALVYVHQVQPTDTITGVTIRYGCQAAIFRKVNGFWPSDSIQARKTVLLPVDCCSIKGRPVKAREETDLLQDVPSRPSIEDPSGSSIVPAPSPEKSTFSRISEQPGTEPEAESDQIWKHESWVQIDGFAEPVEIGRVPRRALGFFPRTRRKSVSYSDSEPVRGRLQTPTISTASSPIQPSSSPNADQHDSYHAGSPASRGPGSKPKGRHRRRPSGLELSGTGVGTLDRNVNLPGPAMDGLSKFFAQHLPTLAPKQAPPNFDSLSGNSSTVASINSTSLDSIGGAVEGWVRKITARAKSSINDLQQGTSSSQNQAMPPETRRRGFSDLIELEDGVESRNSSGLLAGTGWKPDLTRSGSGYVNGANLRERFPSASPSTSRTRTGLDRTKGD
What are the official names of this protein?
Uncharacterized protein AN12072.
Protein: VTU4_DROMA
Sequence: MKIVALTLVAFVALAGASCPYAAPAPAYSAPAAPSGYPAPPCPTNYLFSCQPNLAPAPCAQEAQAPAYGSAGAYTEQVPHYVGSPNREQVQQFHQRIGMAALMEELRGLGQGIQGQQY
What is the function of this protein?
Major early eggshell protein.
What are the official names of this protein?
Vitelline membrane protein Vm32E.
What is the protein family that this protein belongs to?
Belongs to the vitelline membrane family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS8_AQUAE
Sequence: MIPQRIKELEAYKTEVTPASVRLSSNEFPYDFPEEIKQRALEELKKVPLNKYPDPEAKELKAVLADFFGVKEENLVLGNGSDELIYYLSIAIGELYIPVYIPVPTFPMYEISAKVLGRPLVKVQLDENFDIDLERSIELIEKEKPVLGYFAYPNNPTGNLFSRGKIEEIRNRGVFCVIDEAYYHYSGETFLEDALKREDTVVLRTLSKIGMASLRVGILIGKGEIVSEINKVRLPFNVTYPSQVMAKVLLTEGREFLMEKIQEVVKERERMYDEMKKIEGVEVFPSKANFLLFRTPYPAHEVYQELLKRDVLVRNVSYMEGLQKCLRVSVGKPEENNKFLEALEESIKSLSSSL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: VORA_METTM
Sequence: MTKKVIRKPDSLHEVFERKGGSAPTATHYCAGCGHGILHKLIGEAIDELGIQERSVMISPVGCAVFAYYYFDCGNVQVAHGRAPAVGTGISRAEDTPVVLLYQGDGDLASIGLNETIQAANRGEKMAVFFVNNTVYGMTGGQMAPTTLIGEVTVTCPGGRDPRYAGYPLHMCELLDNLQAPVFIERVSLADPKSIRKAKRAVKRALEIQRDGKGYAFVEVLSPCPTNLRQDAEGAERFLKEEMEREFPVKNFRDRSSETEPLIRSESDFSRESLDRIFQIKEDSVPDPVDDPEFREVRVKIAGFGGQGVLSMGLTLAQAACSEGRHTSWYPAYGPEQRGGTSSCGVVISGERVGSPAVDTPDVLVAFNQPSLDEFAGDVREGGIVLYDTATADFSKKENLRAIGVPALEIAKEHGTGRAANTAMLGVMMALGITGLDEESFRDAIRFTFSGKDKIIDINLKILEAGADWARKNLEGEF
What are the official names of this protein?
Ketoisovalerate oxidoreductase subunit VorA, VOR, 2-oxoisovalerate oxidoreductase alpha chain, 2-oxoisovalerate-ferredoxin oxidoreductase subunit alpha.
Protein: HLDE_SALCH
Sequence: MKVNLPAFERAGVMVVGDVMLDRYWYGPTCRISPEAPVPVVKVNTVEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKTLAEVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALGSIGALVLSDYAKGALTSVQTMISLARQAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVAGKCKSEDELVERGMKLIADYDLSALLVTRSEQGMTLLQPNKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNTLEEACYFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELRQAVASARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGESRPVNPLEQRMIVLGALESVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSEEVWANGGEVMVLNFEDGCSTTNIIKKIQTESEK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: DBLOH_XENTR
Sequence: MASLPRRLIWSFSYILRESFPIVSRRNCVSLLRASWRKVLSVGVGTSVCAIPVGQRSEPTLSSESLIKRAVSLVADSSSTFLSQTTYALVESLTEYTTAVYTLISLQQKYTSLLDKMNSNEESAIWQVIIGARVQMKQLKEQYLKYESSWQRAVSLSEMAAEAAYQSGADQASVTVRNHIQIVQTQVQQARNQAHIAEVQLAASQTDEIKRTITEDKGNPPSGGSPRSSLSEEEEIPEAYLRED
What is the function of this protein?
Promotes apoptosis.  Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP) (By similarity).
What are the official names of this protein?
Diablo homolog, mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase, Smac protein.
What are the subcellular locations of this protein?
Mitochondrion. Note=Released into the cytosol when cells undergo apoptosis.
Protein: GATA6_RAT
Sequence: MALTDGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSSSCSRGGDRGPCGASNCRTPQLDTEAVAGPPGRSLLLSPYTSHPFAAAHGAAAPGVAGPGSALSTWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAAEQPEEMYQTLAALSSQGPAAYDGAPGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPYLQGAGSGPSNHAGGAGAHPGWPQASADSPPYGGGGAAGGGAAGPGGAGSATAHASARFPYSPSPPMANGAARDPGGYVAAGGAGAGSVSGGGGSLAAMGGREHQYSSLSAARPLNGTYHHHHHHHPTYSPYMGAPLTPAWPAGPFETPVLHSLQSRAGAPLPVPRGPSADLLEDLSESRECVNCGSIQTPLWRRDGTGHYLCNACGLYSKMNGLSRPLIKPQKRVPSSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKACSGNSSVPMTPTSSSSNSDDCTKNTSPPTQSTASGVGASVMSAVGESANPENSDLKYSGQDGLYIGVSLSSPAEVTSSVRQDSWCALALA
What is the function of this protein?
Transcriptional activator that regulates SEMA3C and PLXNA2.  May regulate genes that protect epithelial cells from bacterial infection.  Involved in gene regulation specifically in the gastric epithelium.  Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.  Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions.
What are the official names of this protein?
Transcription factor GATA-6, DNA-binding protein GATA-GT2, GATA-binding factor 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: KN10B_ARATH
Sequence: MVDSKTPAKTKLLDSSSISNVRVVLRVRPFLPREISDESCDGRSCVSVIGGDGGDTSEVAVYLKDPDSCRNESYQLDAFYGREDDNVKHIFDREVSPLIPGIFHGFNATVLAYGATGSGKTFTMQGIDELPGLMPLTMSTILSMCEKTRSRAEISYYEVYMDRCWDLLEVKDNEIAVWDDKDGQVHLKGLSSVPVKSMSEFQEAYLCGVQRRKVAHTGLNDVSSRSHGVLVISVTSQGLVTGKINLIDLAGNEDNRRTGNEGIRLQESAKINQSLFALSNVVYALNNNLPRVPYRETKLTRILQDSLGGTSRALMVACLNPGEYQESLRTVSLAARSRHISNNVSLNPKVETPKVKIDMEAKLQAWLESKGKMKSAHRMMAIRSPLMGTNQTSISQSSVKKLLCHRSAIAESAKLAGTGQRDAFVTARNLFGVETLAASHLWEPIRNLQLASPTKEDERDTSGEENLLVSEASLRDNTLDVEKKYTELSPLREALSPIDSNAKPNSAHGSSPFLKPMTPKTPFLSTNPEIMQMEGTCQKFNAWSNNLKTSLIKEYIHFLNTANREELRELKGIGQKMAEYIIELRETSPLKSLTDLEKIGFTSRQVHNLFKKATEGVLEKPVSASTTP
What are the official names of this protein?
Kinesin-like protein KIN-10B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-10 subfamily.
Protein: DNJ72_ARATH
Sequence: MVDHYQVLGVTRNATKKEVKDAFRRLAIKYHPDKHAQSPEHVRHNATVRFKLVSEAYEVLNDDLKRASYNAGSDSDCFRRTSGSYSNPYGNRGGRAQGSGYGYGYGYSTRNRQASSFSSGFDSTFRYLTTRAFLLNLALAGGLYFAFTAIDTSGETLWKMRNSGKSFEEAMESIEKSKSHKDEG
What is the function of this protein?
Plays a continuous role in plant development probably in the structural organization of compartments.
What are the official names of this protein?
Chaperone protein dnaJ 72, AtDjC72, AtJ72.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family. C/III subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RR4_SPHDO
Sequence: MSRYRGPRVRIIRRLGTLPGLTNKTPQLKSGSINQSTSNKKISQYRIRLEEKQKLRFHYGITERQLLNYVRIARRAKGSTGEVLLQLSEMRLDNVIFRLGMAPTIPGARQLVNHRHILVNDYIVDIPSYRCKPQDFITIKNQQKSETIISKNIEFYQKSKIPNHLTYSSLEKKGLVNQILDRESIGLKINELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CAS2_ALLVD
Sequence: MSSRLAVFAYDIRDDRVRRHALKTLREWRLDGQLSVHECQVDAIQARRLFEQLGDELDPATDAWLFTWVEGHRAVLARGKGRTTALQDGLLLAA
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: S35F5_BOVIN
Sequence: MVPPRHHPGAGRPGALSSSPPFRLRSSKFSGIALQDLRKAFKIRLQMVCVFIMNRMNSQSSGFTQRKRMALGIVILLLVDVIWVASSELTSYVFTQYNKPFFSTFAKTSMFVLYLLGFIVWKPWRQQCTRGFRGKHATFFADAEGYFAACTTDTTMNSSLSEPLYVPVKFHDLPSEKPENTNIDTEKIPKKSRVRFSNIMEIRQLPSSHALEAKLSRMSYPTVKEQESLLKTVGKLTATQVAKISFFFCFVWFLANFSYQEALSDTQVAIVNILSSTSGLFTLILAAMFPSNSGDRFTLSKLLAVILSIGGVVLVNLSGSEKSPGRNTIGSIWSLVGAMLYAVYIVMIKRKVDREDKLDIPMFFGFVGLFNLLLLWPGFFLLHYTGFEDFEFPNKVVLMCIVINGLIGTVLSEFLWLWGCFLTSSLIGTLALSLTIPLSIIADMCMQKVQFSWLFFAGAIPVFFSFFIATLLCHYNNWDPVMVGIRRIFAFICRKHRIQKVPEDSEQCESLIPMHGVSQEDGAS
What is the function of this protein?
Putative solute transporter.
What are the official names of this protein?
Solute carrier family 35 member F5.
What is the protein family that this protein belongs to?
Belongs to the SLC35F solute transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUTA_SHIDS
Sequence: MQDAVPRLTFTLRDEERLMVKIGVFVPIGNNGWLISPHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGSGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAVRMKQAAEQTGRDVGSYILFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPSAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPVLTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: RHAM_SALDC
Sequence: MIRKAFVMQVNADAHEEYQRRHNPIWPELEAVLKSHGAHHYAIYLDQERNLLFATVEIESEERWNAVASTDVCQRWWKHMRDVMPANPDNSPISAELKEVFYLQ
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_BRASB
Sequence: MSSLRHATEIATTRWPAAAEPRPAALNHLHQLEAESIAILREVAAEFRKPVMLYSIGKDSSVLLHLAMKAFHPAKPPFPLLHIDTTWKFRDMIAFRDQRARELGLELLVHVNPEGLAQKISPFTHGSALYTDVMKTQALRQALDAHGFDAAIGGARRDEEKSRAKERIFSHRSATHRWDPKNQRPELWHLYNTMLAPGESMRVFPLSNWTELDVWDYIQLERIPIVPLYFAARRPVVERDGALIMVDDERMPLRPGETPQWRSIRFRTLGCYPLTGATPSTASDLAAIIREMRTSRTSERQGRVIDRDSAASMERKKVEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: PBUE_BACSU
Sequence: MNFKVFLLAASTIAVGLVELIVGGILPQIANDLDISIVSAGQLISVFALGYAVSGPLLLALTAKIERKRLYLIALFVFFLSNLVAYFSPNFATLMVSRVLAAMSTGLIVVLSLTIAPKIVAPEYRARAIGIIFMGFSSAIALGVPLGILISDSFGWRILFLGIGLLALISMLIISIFFERIPAEKMIPFREQLKTIGNLKIASSHLVTMFTLAGHYTLYAYFAPFLEETLHLSSFWVSICYFLFGISAVCGGPFGGALSDRLGSFKSILLVTGSFAIIMFLLPLSTSSMIFFLPVMVIWGLLSWSLAPAQQSYLIEIAPDSSDIQQSFNTSALQVGIALGSAIGGVVLDQTGTVVSTAWCGGSIVIIAVLFAFISLTRPVQTAKKSSL
What is the function of this protein?
Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and inosine, as well as purine bases guanine, adenine and hypoxanthine, and purine base analogs 2,6-diaminopurine, 6-mercaptopurine and 2-fluoroadenine.  Therefore plays a role in maintaining the cellular purine base pools and protecting cells against toxic purine base analogs.  Modulates expression of the purR and G-box regulons.
What are the official names of this protein?
Purine efflux pump PbuE.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. PbuE (TC 2.A.1.2.25) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KAD_CALBD
Sequence: MRLILLGAPGAGKGTQAEYLSKRFSIPHISTGDILRENVKNETELGKKAKEYMDKGLLVPDEIVIEIVKDRLSKEDCKNGFLLDGFPRTIAQAEALDKVLEELGQKIDKVLNIEVPDEKILERMSGRRICKNCGASFHVIYRPPQKEGVCDVCGGELYQREDDKEETVKKRLEVYHAQTQPLIDYYKAKGLLVVAYGQEEIADTTKEVLKALGIE
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAR3_MOUSE
Sequence: MPGMKRTMSSECLLPYYTAHSYRSMGVFNTSMGNLQRQLYKGGEYDIFKYAPMFESDFIQISKRGEVIDVHNRVRMVTVCIASTSPVLPLPDVMLLARPAKVCEEHARRARFIKGKGCKPSKTLELTRLLPLKFVKISVHDHEKQQLRLKLATGRTFYLQLCPSSDAREDLFCYWEKLVYLLRPPMTNCISNSTLPTGETSVDTKSTLVSEIRGEGDQNSRPQSSPTVSEATSAAFAGGERTQPAAAAAVTPVSAKARAAGTAGAAAGTAGAAAGTAGPAAGPAAGTAGPAAGTAGAAAGTAGAAAGTAGATAGTAGATAGMAGATAGTAAETAGTAAETAGAARAAGGPMAAAVAAPSAGMTKAETATSPTSGVISLAATTTKPPGSGQVAAAMIGSAAKDQVGGESSKAMALAANITLENVDVALAGAANSISESPPAGGDASGSPDTGLNVAFAGSIKTKSPAEDKPEAPLVSTLQSEGYMCERDGSQKVSQTSSEAKEKRERREKDRTSSRKSSHHRRTGMSRHSSKDKSRKTSSYRSVSGKTREDKGKGHGRLRGKRHSSSHKSESRTGHKTRKNRSPAGLGSVSKRATKITSFFRSFLVRPTPKAGDTSCDRGGVDIVTKLVEKKQDIEAVMEKSKDSEFKDTVISETMEKIILETKSI
What is the function of this protein?
May be involved in RNA biogenesis.
What are the official names of this protein?
Golgi-associated RAB2B interactor protein 3, Protein FAM71B.
What is the protein family that this protein belongs to?
Belongs to the GARIN family.
What are the subcellular locations of this protein?
Golgi apparatus. Nucleus, Cajal body.
Protein: MTLD_STRR6
Sequence: MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEKGKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELLAKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAVDRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVNSGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHKVIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFDYRDVNDEESIRLGELLAKQLVKDVVIQVTGLDDQELIEQIVEYI
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: IOLG_RHOJR
Sequence: MSGSNDLRIAVLGVGMMGADHVARITERIKGATVAVVNDYFIEKAEQIAAGIPGCRVIGDPLDAIADPDVDAVVLATPGPTHEKQLLACLEHGKPVMCEKPLTTDVATSLEIVKREAELGKKLIQVGFMRRFDHEYEQLKTLIDDGTFGQVLLAHCVHRNPAVPPSFDSSMIVKDSLVHEVDVTRFLFDEEITSVHILRPAANPGAPEGLQDPQIALFSTESGRHVDVEVFVTTGVAYEVRTEIVAEKGSAFIGLDVGLVRKFGTGAGNGRSGAGMSGGEITPSFKERFGQAYDVEIQRWVNAARTGAETGNYIDGPGAWDGYAAAAVCAAGVQSLETGERVAVDMVDRSSIPGAEPAERPIGPGA
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: SLT2_YEAST
Sequence: MADKIERHTFKVFNQDFSVDKRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLSIWHDPADEPVCSEKFEFSFESVNDMEDLKQMVIQEVQDFRLFVRQPLLEEQRQLQLQQQQQQQQQQQQQQQQPSDVDNGNAAASEENYPKQMATSNSVAPQQESFGIHSQNLPRHDADFPPRPQESMMEMRPATGNTADIPPQNDNGTLLDLEKELEFGLDRKYF
What is the function of this protein?
Serine/threonine protein kinase involved in a signal transduction pathway that plays a role in yeast cell morphogenesis and cell growth.  This pathway seems to start by SMP3; then involve the kinase PKC1 that may act the BCK1 kinase that then phosphorylates MKK1 and MKK2 which themselves phosphorylate the SLT2/MPK1 kinase which itself then phosphorylates and activates the transcription factor RLM1.  Directly phosphorylates BCY1 upon TOR complex 1 (TORC1) inhibition.
What are the official names of this protein?
Mitogen-activated protein kinase SLT2/MPK1, MAP kinase MPK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: UBIG_RHOP5
Sequence: MAMQSETPGNPASTVDPAEIAKFSKLSAEWWDPTGRMAPLHKINPHRVAFIRDAACRKFDRNPKSLNSLAGLRMIDIGCGAGLLCEPFTRLGAQVIGIDPSATNIAAAKVHAEKSRLLIDYRNTTAEAMDPRERFDIVLAMEVIEHVTDVGAFLGRCAAMMKPTGLMVVATLNRNWKSFALAIVGAEYVMRWLPRGTHQWDKFVTPEELTRHLQNSRLAVTEQAGLVYNPLADKWNLSADMDVNYMMVAESAG
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.