PharMolix/UniProtQA huggingface dataset:
Protein: GLYA_SULIA
Sequence: MSFPKELEKVLEITKAQNVWRRTQTLNLIASENVMSPLAESVYMSDFMSRYAEGKPYKRYYQGTKYTDEIETLAMDLMNEITNSKDCDLRPTSGTIANAAVFRVLAEPGDKALIAPVQAGAHVSHTKFGTLGALGIQHIEMPFDEENINVDVDKAIKMIEEVKPKFVVLGGSLYLFPHPTKELAPHVHAVGAKLVYDAAHVYGLIEGKVWSSPLKEGADIMTVSTHKTFPGPQGGAIFSDGSEVFKQVSRTIFPWFVSNHHLHRLPATAVTAIEMKYFGESYANQITRNSKALAEALAERGFKVIGENLGYTKSHQVAVDVRQFGGGNKIAKLLEDANIIVNKNLLPYDKPENVSDPSGLRIGVQEMTRYGMKESEMEEIAELFKKVIIDKKDVNEVKKEVIDMRKNFLEVKYTFDDMKDLEKYSSKSLKLII
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU_LEIXX
Sequence: MRAIWTGAITFGLVNVPVKVYSATEDHDVPLQPLHAADGGRIRYQRRCEIDGKVIPYEDIARAYDDGERMVVLTPEDLASLPAERSREIDVVEFVPDEQLDPLTFDRSYYLEPDSRSVKAYALLRTTLEDGCRTAIVTVALRQKTRLGALRVRGNLLVLQTLLWHDEIRAAAFPSLETVPPITERELALSSALMESFAGDFQPETFADEYQEELRKLIAAKIEQGESVDVAETFGEGAAPAGGGAVIDLMEALQRSVERSGGKAASAFPAAEKAPAGKNAATASAKKARKLA
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: VIT_APIME
Sequence: MLLLLTLLLFAGTVAADFQHNWQVGNEYTYLVRSRTLTSLGDLSDVHTGILIKALLTVQAKDSNVLAAKVWNGQYARVQQSMPDGWETEISDQMLELRDLPISGKPFQIRMKHGLIRDLIVDRDVPTWEVNILKSIVGQLQVDTQGENAVKVNSVQVPTDDEPYASFKAMEDSVGGKCEVLYDIAPLSDFVIHRSPELVPMPTLKGDGRHMEVIKIKNFDNCDQRINYHFGMTDNSRLEPGTNKNGKFFSRSSTSRIVISESLKHFTIQSSVTTSKMMVSPRLYDRQNGLVLSRMNLTLAKMEKTSKPLPMVDNPESTGNLVYIYNNPFSDVEERRVSKTAMNSNQIVSDNSLSSSEEKLKQDILNLRTDISSSSSSISSSEENDFWQPKPTLEDAPQNSLLPNFVGYKGKHIGKSGKVDVINAAKELIFQIANELEDASNIPVHATLEKFMILCNLMRTMNRKQISELESNMQISPNELKPNDKSQVIKQNTWTVFRDAITQTGTGPAFLTIKEWIERGTTKSMEAANIMSKLPKTVRTPTDSYIRSFFELLQNPKVSNEQFLNTAATLSFCEMIHNAQVNKRSIHNNYPVHTFGRLTSKHDNSLYDEYIPFLERELRKAHQEKDSPRIQTYIMALGMIGEPKILSVFEPYLEGKQQMTVFQRTLMVGSLGKLTETNPKLARSVLYKIYLNTMESHEVRCTAVFLLMKTNPPLSMLQRMAEFTKLDTNRQVNSAVKSTIQSLMKLKSPEWKDLAKKARSVNHLLTHHEYDYELSRGYIDEKILENQNIITHMILNYVGSEDSVIPRILYLTWYSSNGDIKVPSTKVLAMISSVKSFMELSLRSVKDRETIISAAEKIAEELKIVPEELVPLEGNLMINNKYALKFFPFDKHILDKLPTLISNYIEAVKEGKFMNVNMLDTYESVHSFPTETGLPFVYTFNVIKLTKTSGTVQAQINPDFAFIVNSNLRLTFSKNVQGRVGFVTPFEHRHFISGIDSNLHVYAPLKISLDVNTPKGNMQWKIWPMKGEEKSRLFHYSVVPFVSNHDILNLRPLSMEKGTRPMIPDDNTSLALPKNEGPFRLNVETAKTNEEMWELIDTEKLTDRLPYPWTMDNERYVKVDMYMNLEGEQKDPVIFSTSFDSKVMTRPDTDSENWTPKMMAVEPTDKQANSKTRRQEMMREAGRGIESAKSYVVDVRVHVPGESESETVLTLAWSESNVESKGRLLGFWRVEMPRSNADYEVCIGSQIMVSPETLLSYDEKMDQKPKMDFNVDIRYGKNCGKGERIDMNGKLRQSPRLKELVGATSIIKDCVEDMKRGNKILRTCQKAVVLSMLLDEVDISMEVPSDALIALYSQGLFSLSEIDNLDVSLDVSNPKNAGKKKIDVRAKLNEYLDKADVIVNTPIMDAHFKDVKLSDFGFSTEDILDTADEDLLINNVFYEDETSCMLDKTRAQTFDGKDYPLRLGPCWHAVMTTYPRINPDNHNEKLHIPKDKSVSVLSRENEAGQKEVKVLLGSDKIKFVPGTTSQPEVFVNGEKIVVSRNKAYQKVEENEIIFEIYKMGDRFIGLTSDKFDVSLALDGERVMLKASEDYRYSVRGLCGNFDHDSTNDFVGPKNCLFRKPEHFVASYALISNQCEGDSLNVAKSLQDHDCIRQERTQQRNVISDSESGRLDTEMSTWGYHHNVNKHCTIHRTQVKETDDKICFTMRPVVSCASGCTAVETKSKPYKFHCMEKNEAAMKLKKRIEKGANPDLSQKPVSTTEELTVPFVCKA
What is the function of this protein?
Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development (By similarity).  Involved in the differentiation of honeybee larvae into queens.
What are the official names of this protein?
Vitellogenin.
What are the subcellular locations of this protein?
Secreted.
Protein: TACHY_DROPS
Sequence: MRSQGGSFAVALLLLLLLTAAATAADAEPDVESSVSTLPPGADAPRRMVKRAPTSSFIGMRGKKEDEKDQRAADWMGPDPLDYADMDEDSIYYENGKRLKKAPMSFVGMRGKKYIPISNRLSDVLHQIEEQRMRENLLEDLFERLAAGDDSVGDVGKRAPTGFTGMRGKRPMSGDDDDNDAMELLQKRAPVNSFLGVRGKKDVSHQHYKRAALSEAYDVRGKKERYADFNSKFVAVRGKKSEQEAGLDTGDGDGDQQYLVRPWLYLWADNKRAPSGFQGMRGKRPALAE
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.  Stimulates gut muscle contractions (By similarity).
What are the official names of this protein?
Tachykinins.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMBR_PYRFU
Sequence: MEIPPEISHALSEIGFTKYEILTYWTLLVYGPSTAKEISTKSGIPYNRVYDTISSLKLRGFVTEIEGTPKVYAAYSPRIAFFRFKKELEDIMKKLEIELNNVKKEEQRPAIWRSRSFDEAIEMFRESLYSAKNEVIVVTPSEFFETIREDLIKTLERGVTVSLYIDKIPDLSEFKGKGNFFVRQFYKLNHLIGMTDGKEVVTIQNATFDSIGPPSFKSTYPEIIFSQYSLIIEIFKESTLEKEIIGNPKDIRFFAMFHAVDFVKNHLKNRNIYAEITGKNLESGRLETLTGRVVGYTLSLREAVNNIHLETENGVVKVGGMFAVIEDYESTEIKFIMG
What is the function of this protein?
Inhibits transcription of the trehalose/maltose transport gene cluster (malE operon) and of the maltodextrin transport gene cluster (mdxE operon).  Acts by binding to two different operator sequences in both promoters, preventing polymerase recruitment and transcription.
What are the official names of this protein?
HTH-type sugar sensing transcriptional regulator TrmB.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulator TrmB family.
Protein: MSA2_PLAFK
Sequence: MKVIKTLSIINFFIFVTFNIKNGSKYSNTFINNAYNMSIRRSMANEGSNTKSVGANAPKADTIASGSQSSTNSASTSTTNNGESQTTTPTAADTPTATESNSRSPPITTTESNSRSPPITTTESNSRSPPITTTESNSRSPPITTTESNSRSPPITTTESSSSGNAPNKTDGKGEESEKQNELNESTEEGPKAPQEPQTAENENPAAPENKGTGQHGHMHGSRNNHPQNTSDSQKECTDGNKENCGAATSLLNNSSNIASINKFVVLISATLVLSFAIFI
What is the function of this protein?
May play a role in the merozoite attachment to the erythrocyte.
What are the official names of this protein?
Merozoite surface protein 2, Merozoite surface antigen 2, MSA-2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: C3H41_ARATH
Sequence: MELSVSSPKQSVLSPPDCMSDPEEEHEISEEEDDDRNHKHRRKEETRSQSLEQDSSDQAFSRPYRKNYRHYENGNSFSEHEKRSFGTGSGQRVQFDNQRMRSNPMFSRDSGPGRGRGNYGSWAQRDSRFNPVDLSSHMVQVGSMGQGMFGGRGLAGVSAAQSAPWPPFGMIPGVPNGGLDGFHHLQGSLRPPLNAPLNMGIPRQRCRDFEERGFCLRGDMCPMEHGMNRIVVDDVQSLSQFNLPVSVPGAPHLAASSKQVPAQFGGASFMNPKGAHGRTNEGGMAVDGLGYGDAYPSAGGTDFYDPDQPLWNNSTGETSGAISTLNSHGVDENVAPLDDSNQDAAENGCGIRDSRSTSQSVWGRMKGSNSQANSKEKADAVLNSSAVPEDQLKEVSVNSSRHGKQNHVGESVAKVVDSSNISNDMMNNTRKPTQKAMRTLFVNYVPHESNRRDLILAHFQKFGKVIDIHIPVNSERAFVQFSKREEAESALRAPDAVMGNRFIKLWWANRDSIPDNGLSTGSGASMKGRSMTASGAQNQFPIAAASKSNHVSSIAKVPTFQTGGAPSSSEQPKPVVVTTSGPKVTPLQQKKADTLERLKETLRKKQEMLEQKRNEYRKKLATLEKQGTVVKREEADEPDAKRVKLDTASDSGAAIASPKTESSTDKKVPILKPLSTAKLSTETPSPDSKNFKQRPYSFTTSLNAPMVNRYKLDNRTTTIKVVPPLPTGLADVAVVKEHFSSYGEVSKVELEDNASIDSGKDHETQNESRAACVTFVKRSAAEKAFANAKCWQEHTLQLVWVTRQSNRESNNNNNNSNSLSVSRDNLSSKNKCASVSNDPKPAVEVKTSSTEEPENTNVSGDNDSTLDKQETKESDNDNNKSNHESIEGASEVIATAGTDEEQSEQIHQ
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 41, AtC3H41.
Protein: FUMC1_BRADU
Sequence: MNDLRKETDSLGEVNVPADKLWGAQTQRSLEHFSIGRDLMPREMIQSYAILKKAAANANYAGGRLDGKIHKLIVHTCDEILAGQHHDMFPLHVWMTGSGTQFNMNVNEVISNRCCQLAGTALGSKLPVHPNDHVNMSQSSNDSFPSAMYIAAAMNVTQRLVPAVEALHDAIAAKSNQWDDIVKIGRTHMQDATPLTLGQEWSGYAAMLADGLARIDDALKGVFRLALGGTAVGTGINAAPGFAEAVAAEIARLTGLPFVSAPNKFAVQGAHDALVQLSGTLRTLAGSLYKIANDIRLLSCGPRAGFAELRIPENEPGSSIMPGKVNPTQAEALTMIAVQVMANDVAVGFGGAGGYLEMNVYKPLIIHNIAQSVTILTDGCTNFRTFLVEGTEPNRKKIKEYVERSLMLVTALAPVIGYDKASRIAHYAMDNDLTLKSAALKLGFVTEPEFDRIVDPAKMVKPYVAEIKVPLAIGAKTG
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II 1, Fumarase C 1, Aerobic fumarase 1, Iron-independent fumarase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCP_PERVT
Sequence: SDLWVQKMKTYFNRIDFDKDGAITRKDFESMATRFAKESEMKPEHAKVLMDSLTGVWDKFLANVAGGKGIDQATFISSMKEKVKDPNAKAVVEGPLPLFFRAVDTNEDNMISRDEYGIFFNMLGLNPDMAPASFDAIDTNNDGLLSQEEFVTAGSDFFINDQDSPNKVFWGPLV
What is the function of this protein?
Like parvalbumins, SCPs seem to be more abundant in fast contracting muscles, but no functional relationship can be established from this distribution.
What are the official names of this protein?
Sarcoplasmic calcium-binding protein, SCP.
Protein: SYC_ECOLI
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVAMVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_HELPY
Sequence: MRCFKATIAYDGAYFLGYAKQPNKLGVQDKIEDALNALGIKSVVIAAGRTDKGVHANNQVLSFHAPKHWNAAKLFYYLAPKLAPHIVLKKLEEKNFHARFDAQKRAYRYLLTKNLKTPFLAPYIACGDYGSLDALNTALKQFTGKHDFSMFKKEGGATTNPKRTIFNAFAYKTFIIGHECVVFKIIGDAFLRSSVRLIIQACVQYSLEKITLAEIQAQIHNLKATIRTPIMANGLYLHRVYY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: AMD_MOUSE
Sequence: MAGRARSRLLLLLGLLALQSSCLAFRSPLSVFKRFKETTRSFSNECLGTTRPITPIDSSDFTLDIRMPGVTPKESDTYFCMSMRLPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSLHLTRVPQPLIAGMYLMMSVNTVIPPGEKVVNSDISCHYKMYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVEHPVDVAFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPEEANIPIPVKSDMVMIHGHHKETENKEKSALIQQPKQGEEEAFEQGDFYSLLSKLLGEREDVVHVHKYNPTEKTESGSDLVAEIANVVQKKDLGRSDAREGAEHEEGGNAILVRDRIHKFHRLESTLRPAESRALSFQQPGEGPWEPELAGDFHVEEALEWPGVYLLPGQVSGVALDSKNNLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNKAEILQSSGKNLFYLPHGLSIDTDGNYWVTDVALHQVFKLEPRSKEGPLLVLGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPKPGQFSVPHSLALVPHLNQLCVADRENGRIQCFKTDTKEFVREIKHASFGRNVFAISYIPGFLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKPVRKHFDMPHDIVASEDGTVYIGDAHTNTVWKFTLTESRLEVEHRSVKKAGIEVPEIKEAEAVVEPKVKNKPTSSELQKMQEKKKLIKDPGSGVPVVLITTLLVIPVVVLLAIAMFIRWKKSRAFGDHDRKLESSSGRVLGRLRGKGSSGLNLGNFFASRKGYSRKGFDRVSTEGSDQEKDEDDGSESEEEYSAPLPTPAPSS
What is the function of this protein?
Bifunctional enzyme that catalyzes the post-translational modification of inactive peptidylglycine precursors to the corresponding bioactive alpha-amidated peptides, a terminal modification in biosynthesis of many neural and endocrine peptides (By similarity).  Alpha-amidation involves two sequential reactions, both of which are catalyzed by separate catalytic domains of the enzyme.  The first step, catalyzed by peptidyl alpha-hydroxylating monooxygenase (PHM) domain, is the copper-, ascorbate-, and O2- dependent stereospecific hydroxylation (with S stereochemistry) at the alpha-carbon (C-alpha) of the C-terminal glycine of the peptidylglycine substrate (By similarity).  The second step, catalyzed by the peptidylglycine amidoglycolate lyase (PAL) domain, is the zinc-dependent cleavage of the N-C-alpha bond, producing the alpha-amidated peptide and glyoxylate (By similarity).  Similarly, catalyzes the two-step conversion of an N-fatty acylglycine to a primary fatty acid amide and glyoxylate (Probable).
What are the official names of this protein?
Peptidyl-glycine alpha-amidating monooxygenase, PAM.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein. Note=Secretory granules.
Protein: DIVIB_OENOB
Sequence: MRLSSHGKKTVSTSNNPVFNRIGLFFTAAILFALFLQMLFFLRPWQDIKETKVYTFQMDYRQVLKKVDLKVGDPYWRWAGQGQTINRRIKNDSMIRSLSLRLSKNGTAIIRVNENLTAGFVQIKQKWYRMDQNAHLSSKSIQPDGKTPVYTDFKNGSKILKKTITAYLSMDKVMRLAVAQIIYSPVKSSPNRLALVMNDGNLVYANPSSLAKRMDLYPKMVATMEEKGIKNGVIDLQYGGYARKFENSDDNLLSSLSSDKSKSSSKSSNSSK
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: ISPE_PROA2
Sequence: MQSISVKAYAKINLGLLITGKRPDGYHTLETVFAPINWYDELTFSPSQEVRMSCTNQDLPCDDSNLCIRAAKALRDFSGVSSGVEIGLAKHIPFGAGLGGGSSDAASTLRVLNRMWNINASSHDLHRIAVGLGADVPYFLESGGLAYAAGIGEELEDLELTLPFSIVTLFPGDHISTVWAYRNFYACFEREIPDLKGLVRSLCQARDTSVLEVFDNDFEPVVFDHYPAVREAKDALVQSGSFFASLSGSGSAVFGLFENDSDAERAAEQLSATYRARFTPASFAMA
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PIP_XYLFA
Sequence: MRTLYPEVTPFEHGILCVDDNHRLYYEQCGNPHGKPVVILHGGPGSGCNDKMRRFHDPDKYRIVLFDQRGAGRSTPHANLTNNTTWDLVADIEKLRVALGITRWQVFGGSWGSTLALAYAQTHPEQTTELVLRGIFMLRRWELEWFYQEGASHLFPDAWDRYIAVIPPVERHDLISAFHRRLTSEDEATRLAAAQAWSLWEGATSCLYMDQDFIASHENPHFALAFARIENHYFVNGGFFEVENQLLRDAQRIANIPGVIVHGRYDVVCPLQNAWDLHKVWPKASLKITPGAGHSAFEPQNIDALVCATDSFV
What is the function of this protein?
Specifically catalyzes the removal of N-terminal proline residues from peptides.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_SHIB3
Sequence: MSAIENFDAHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAGLQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEDVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MYB14_ARATH
Sequence: MGRAPCCEKMGVKRGPWTPEEDQILINYIHLYGHSNWRALPKHAGLLRCGKSCRLRWINYLRPDIKRGNFTPQEEQTIINLHESLGNRWSAIAAKLPGRTDNEIKNVWHTHLKKRLSKNLNNGGDTKDVNGINETTNEDKGSVIVDTASLQQFSNSITTFDISNDNKDDIMSYEDISALIDDSFWSDVISVDNSNKNEKKIEDWEGLIDRNSKKCSYSNSKLYNDDMEFWFDVFTSNRRIEEFSDIPEF
What is the function of this protein?
Transcription activator that regulates freezing tolerance by affecting expression of CBF genes.
What are the official names of this protein?
Transcription factor MYB14, Myb-related protein 14, AtMYB14, MYB14At.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUSB_MYCGI
Sequence: MPDRKGDRGRHQARKRAVDLLFEAEARGITAAEVAEARNALADNGADDIAPLNPYTVTVARGVTDHAAHIDDLISAHLQGWTLDRLPAVDRAVLRVAVWELLHAVDVPEPVAVDEAVELAKQLSTDDSPGFVNGVLGQVMLVTPQIRAAAAAVQASPDSGSATP
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: AROB_THEAC
Sequence: MDAQRFVLPMNGENISVVIGEDITGHISEEVGHYDSLVFMISRNVEEMFGSKIPPLENYGSSTIKITLNDGESLKTLRNYQRIIKVLVEKKVSRNSLLVYVGGGTVGDLAGFVAATYKRGLRMIAVPTTLLAQVDSSIGGKNGLDFSDVKNVIGTFYNPYLIIDDLQFLKSTPDLIREGMGEVIKYSIIAGGDMFRKVSECSLSNFHDHSADIVKMSIKIKADIVNRDYYDRNGVRSILNLGHTIAHGIEGASKGQISHGRAVATGLMVEAHIGEKYGNTRPEVIDEIMKLADNYGIERVRISDIGVNSILRYISNDKKMSEGYINMPVPADIGNIITMKVTERMISDGLNTFIREHERK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_GEOSW
Sequence: MKAAWSGFLLSVQFLTVIPIRKQIDWNAATARWSVRAFPLVGALIGVIEAVTYFIFSSFSSLSPLFLALSLMWLSIWIAGGLHADGWMDVSDAFFSYRDIKRRQEIMSDSRVGAFAVLSILCLLSFRFLFVFETIRSHLDIFLISVIPLLSRTAMAWLLIYGKPAKQTGMAAAFREHADRYDAHVAMIIGNCLLACLCAIHFSVWKTVIFLACGTIFAVFVARLFFEKQFGGITGDALGAFVEGVETWLWCMIWLLRSYVMV
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HINT1_RAT
Sequence: MADEIAKAQVAQPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGYRMVVNEGADGGQSVYHIHLHVLGGRQMNWPPG
What is the function of this protein?
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (By similarity).  Hydrolyzes adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate) (By similarity).  Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester (By similarity).  Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide (By similarity).  In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1 (By similarity).  Modulates p53/TP53 levels and p53/TP53-mediated apoptosis.  Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex (By similarity).  Also exhibits SUMO-specific isopeptidase activity, deconjugating SUMO1 from RANGAP1 and RGS17 (By similarity).
What are the official names of this protein?
Adenosine 5'-monophosphoramidase HINT1, 17 kDa inhibitor of protein kinase C, Desumoylating isopeptidase HINT1, Histidine triad nucleotide-binding protein 1, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1, PKCI-1.
What is the protein family that this protein belongs to?
Belongs to the HINT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DNAA_LACAC
Sequence: MFNFEKFWQHFNDEMRARFNEVAYNAWFKNTKPISYNQKTHELKIQVQNPVAKGYWEKNLSSQLIQSAYGYAGVELLPVFQISEDSDTPERIVTPEPQHNLQTTPTRAPQREFAKDLKLNEKYTFDNFVQGEGNKLAAGAALAVADSPGSFYNPLFIFGGVGLGKTHLMQAIGHQMLVERPNAKVVYIQSETFVNDFINSIKNKTQDKFREKYRTCDLLLVDDIQFFAKKEGIQEEFFHTFETLYNDQKQIVMTSDRLPTEIPDLSERLVSRFTWGLQVEITPPDLETRIAILRRKAEAEGLTIDDDTLDYIASQVDTNIRELEGALVKVQAYATIEKADIDINLAREALVDLKLVQKNRGLQIPKIQEVVANYFQTSTAELKGKKRVRQIVIPRQIAMYLSRELTDASLPKIGQEFGGKDHTTVMHAYDKIDKQMKTDADIKTAVFDLKQMLEH
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_LEGPA
Sequence: MARYLGPKCKLSRREGCDLLLKSGVRDHKSKCKSEKLPGQHGDKKPRLNSYGIQLREKQKIRRLYGILEKQFRNYYKKAARQKGSTGENLMALLERRLDNVVYRMGFASTRAEARQLVAHKAILVNDKVVNVPSFLVNPGDTISVRQKAKNQGRIQAALALSEQRAPCDWITVDTGSFKGTFSTAPTLMDLSSDYNVNLVVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: AOTC_XANAC
Sequence: MSLKHFLNTQDWSRAELDALLTQAALFKRNKLGSELKGKSIALVFFNPSMRTRTSFELGAFQLGGHAVVLQPGKDAWPIEFNLGTVMDGDTEEHIAEVARVLGRYVDLIGVRAFPKFVDWSKDREDQVLKSFAKYSPVPVINMETITHPCQELAHALALQEHFGTQDLRGKKYVLTWTYHPKPLNTAVANSALTIATRMGMDVTLLCPTPDYILDQRYMDWAAQNVVESGGSLQVSHDIDSAYAGADVVYAKSWGALPFFGNWEPEKPIRDQYQHFIVDERKMALTNNGVFSHCLPLRRNVKATDAVMDSPNCIAIDEAENRLHVQKAIMAALASQAGIGNRE
What is the function of this protein?
Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-acetyl-L-ornithine to produce N(2)-acetyl-L-citrulline.  This is a step in an alternative arginine biosynthesis pathway.  The enzyme has no activity with ornithine.
What are the official names of this protein?
N-acetylornithine carbamoyltransferase, N-acetyl-L-ornithine transcarbamylase, AOTCase, Acetylornithine transcarbamylase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. AOTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_RHIEC
Sequence: MGLIVYYSSRSENTHRFVARLGLRAARIPASGADAFHIREPFVLVVPTYSGGDGKGAVPKQVIRFLNDAENRGHIRGVIAAGNSNFGETYGLAGDVISRKCQVPYLYRFELIGTAEDVAKVKHGLERFWTRQQL
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.