PharMolix/UniProtQA huggingface dataset:
Protein: ORN_VIBVY
Sequence: MSFSDQNLIWIDLEMTGLDPDVHKIIEIASIVTDSELNILAEGPVLAIHQSEEELAKMDEWCTNTHTGSGLVERVRGSQITEQEAVEQTIAFLEKWVPKGVSPICGNSIGQDRRFLYRHMPELEGYFHYRYIDVSTLKELTRRWNPEVLKGFSKQGTHLALDDIRESIAELKFYRQTIFKI
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORN_RAT
Sequence: MLGVSLGARLLRGVGGRRGQFGARGVSEGSAAMAAGESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTVTLQQAEYEFLSFVRQQTPPGLCPLAGNSVHADKKFLDKHMPQFMKHLHYRIIDVSTVKELCRRWYPEDYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKTDEKKRKIIENGENEKPVS
What is the function of this protein?
3'-to-5'exoribonuclease that preferentially degrades DNA and RNA oligonucleotides composed of only two nucleotides (By similarity).  Binds and degrades longer oligonucleotides with a lower affinity (By similarity).  Plays dual roles in mitochondria, scavenging nanoRNAs (small RNA oligonucleotides of <5 nucleotides) that are produced by the degradosome and clearing short RNAs that are generated by RNA processing (By similarity).  Essential for correct initiation of mitochondrial transcription, degrading mitochondrial RNA dinucleotides to prevent RNA-primed transcription at non-canonical sites in the mitochondrial genome (By similarity).  Essential for embryonic development (By similarity).
What are the official names of this protein?
Oligoribonuclease, mitochondrial, RNA exonuclease 2 homolog, Small fragment nuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Mitochondrion matrix. Mitochondrion. Cytoplasm. Nucleus.
Protein: PHCA_MASLA
Sequence: MVKTPITDAIAAADTQGRFLSNTELQAVNGRYQRAAASLEAARALTANAQRLIDGAAQAVYQKFPYTTQTSGPNYAADARGKSKCARDIGHYLRIITYSLVAGGTGPLDEYLIAGLNEINDAFELSPSWYIEALKYIKANHGLSGQAANEANTYIDYVINALS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of the phycobilisome rod.
Protein: HSLV_CHLL2
Sequence: MGQESKPLIRSTTVLGVIRDGKAALGSDGQMTLGNTVLKHSTRKIRSLYHGRIITGFAGATADAVTLLDRFEEKLDAYGGKLERAAVELARDWRTDKYLRRLEAMLAVVSQDKALIISGTGDVIEPEDSIVAIGSGSMYALAAARSLLKHTPLSAREIVSESLKIAADICIYTNDHIVIEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_NOSS1
Sequence: MLSPRRTKFRKQQRGRMGGLAHRGSTLNFGDFALQAQEPAWITSRQIEASRRAMTRYIRRGGKIWIRIFPDKPVTMRPAETRMGSGKGNPEFWVAVVKPGRILFEIAGVTEEIAREAMRLAAYKLPIKTKFIVRSQVVEEQE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: LRB4B_MOUSE
Sequence: MIAMLTVLLYLALILEPRTAVQAGHLPKPIIWAEPGSVIAAYTSVIIWCWGSWEAQYYYLDKEKSVNPWDTEVPLENRNKTKFKIRFMTASYAGIYNCYYKSAAGFSEHSDAMELVMTGAYENPSLSVYPSSNVTSGVSISFKCSSSTLFGRFILIQEGKHGLSWTLDSQHQANQPTHATFVLDAVAPNHNGTFRCYGFFRNEPQVWSKPSNSLDLMISETKEQSCTPTEDGLETYQKILIGVLVSFLLLFFLLLFLILIGYQCRHKNKANASVKNTQSEDNAELNSWNPQNEDPPRELCTPR
What is the function of this protein?
Plays a role in mast cell activation.
What are the official names of this protein?
Leukocyte immunoglobulin-like receptor subfamily B member 4B, Mast cell surface glycoprotein Gp49A.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PNP_ROSCS
Sequence: MSERRIHSVSMDLAGRTLTLETGRFAEQANGAVVVRYGDTMLLATAVASKEPRTDTDFFPLTVDYEEKMYAAGKIPGSFFKREGKPTEGAILTARLTDRPLRPLFPEGYRNEVQIIVTTFSIDMVNDPAPLSIIAASAALAISDIPFLGPVGAVQVGYIDGALQINPPMPNMANSDLDLVVAGTKEAVLMVEAGANELPEEVMLEAVIQGHQVCKQICDLQNELVKLAGRPKKEFVPPPVDTSLEEAIQQWLGNRLYEAITDANKMVRDAQTEALKREVIAHFTADEPEEELEARTAAVSAAFENILYEEVRRMILERGERVDGRGPKDIRPISVEVGLIPRVHGSGLFTRGQTQVLTLATLGSPAEEQRLDDLGIETAKRYIHHYNFPPFSTGEIRRLGSPRRRDIGHGALAERSLLAVLPPKEEFPYTMRLVSETLSSNGSSSMASVCGSSLALMDAGVPIRAPVAGIAMGLITGKDGRWRVLTDIQGIEDHLGDMDFKVAGTAKGITGLQMDIKTTGITYEIMREAFAQAREGRLHVLEKMNAVISEPRKELSPYAPRIITLQINPEKIGALIGPGGKTIRSITEATGAQIDIEEDGRVYISTADAAAAQQAVAMVEALTREIKVGDIFLGKVVRIMPFGAFVNLAPGKDGMVHVSELDVGRVENVEDVIKMGDEINVMVIGIEPGTGKVSLSRRALLTGETAEDRRAAGAGRGLRDGGRSSGSERSGDRSPRSDDRPRPRRR
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PALC_EMENI
Sequence: MVYPFELPTTSHLSFQSALSSHTHPSLPQSATTARHALRLALKAHNRLPRGFQRDSHLTSVLSAINDYLPYVVALAQGLNNGKPIDTTTPSTTTHLEEIRVAQRAELEPEWRATLASSSLRRPSTNRTRGTGVQYELAFILTTLGYILSSLARSGVTRTLYASTTPSAEQRTAAVQTATKHLLQASTIHSFLSSSPYFATVSEAATLPDLAPATQAALSSLALAEATLLTVLKDDSYVVACIQARNPNDKDWMVRAPEIPKVRAHLFARLCIRAAEYAEQAATGLSSVAAEGRKAGVDEDVARYAHVLGLVARARACRFFGVDAELAGKVGEGIAWLRAAKGALGLRNTGSASAEEVTTKSRGLSKLKLGFRERREERKLEKGAGGERVDKGGLGPGDNAGREEEGRVLEMLETKWVRANDTLNTQLIPSSADYVANLPSGRDVLPPQPPYTPPSLDEERLFQMRGPPTELELNPGSDDGDSDFESQAAGDAHTPGAFPGRADNAYY
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palC.
What is the protein family that this protein belongs to?
Belongs to the palC family.
Protein: XTMA_BACSU
Sequence: MKTQQREQALAIYQQHQGKITNRAIADTIGVSAKTIGIWKKQDKWKEALFSASKNEQKQRPINNDELNERQRLFCLYYVKSFNATQSAIKAGYSPDSAHVTGSRLLKNEKVAAEIRRIKKEMVNEMFIEAMDVLQVYIKIAFADITDYVTFGKKEVQAVGKSGPLFDEDDNPIMKEISFVDVKDSGLVDGTIVTEAKLGKEGIAIKLADKMKALEKLSLYFDLFPDQFKQKIENEKLKLAKQKAEKTDDSQEPIEIMIKRKERKS
What is the function of this protein?
Functions as a terminase.
What are the official names of this protein?
PBSX phage terminase small subunit.
What is the protein family that this protein belongs to?
To B.subtilis YqaS and B.subtilis phage SPP1 terminase small subunit.
Protein: MENB_STAS1
Sequence: MTRQWETIREYKEIKYELYDGIAKVTINRPEVRNAFTPNTVQEMIDAFTRARDDQRISVIILTGEGDKAFCSGGDQKVRGHGGYVGDDQIPRLNVLDLQRLIRVIPKPVVAMVRGYAIGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLDQVEDETVQWCQEMKQHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP
What is the function of this protein?
Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA synthase, DHNA-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
Protein: TSK_CHICK
Sequence: MQFLAWFNMLLLLPCFSTTKTCFPGCHCEVESFGLFDSFSLTKVDCSGIGSHIVPVPIPLDTSYLDLSSNKLETINESMLTGPGYTTLVSLDLSYNNIAKISSTTFSRLRYLESLDLSHNSLEVLPEDCFSSSPLGDIDLSNNKLLDIALDVFASKGQGKPLNVDLSNNMLSKITRNHEKSIPNIQNLNLSGNRLTSVPNLQGIPLRYLNLDGNPLAKIEKGDFKGLKGLIHLSLSGLHDFRELSPYSFKELPALQVLDLSNNPNLRSLTAEVIFGLNSIQELNLSGTGVSSLPKTVLKYLPSLKSITLRKNIQCFKTIKEGQYHRQIGLTKLGLGAEELLWCKTPCPRPVCRCRDKPLQSAPQNLPTP
What is the function of this protein?
Shows weak bone morphogenetic protein antagonistic activity.
What are the official names of this protein?
Tsukushi, C-TSK, Leucine-rich repeat-containing protein 54.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1389_STAS1
Sequence: MPIVNVKLLEGRSDEQLKNLVTEVTNAVEKTTGANKEAIQIVIEEMKASHYGVAGVRKSDQ
What are the official names of this protein?
Probable tautomerase SSP1389.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: PP339_ARATH
Sequence: MRWSIATAIASTAKGFLHLHHHFLKNSNPGIVLSPSLRFRFWVRAFSGTTIDYREVLRSGLHNIKFDDAFHLFVLMAYSYPLPSIVEFNKVLTAIAKMQMYDVVINLWKRIENAEGIEISPDLYTCNILVNCFCRCFQPSSALSYLGKMMKLGIEPDIVTASSLVNGFCLSNSIKDAVYVAGQMEKMGIKRDVVVDTILIDTLCKNRLVVPALEVLKRMKDRGISPNVVTYSSLITGLCKSGRLADAERRLHEMDSKKINPNVITFSALIDAYAKRGKLSKVDSVYKMMIQMSIDPNVFTYSSLIYGLCMHNRVDEAIKMLDLMISKGCTPNVVTYSTLANGFFKSSRVDDGIKLLDDMPQRGVAANTVSCNTLIKGYFQAGKIDLALGVFGYMTSNGLIPNIRSYNIVLAGLFANGEVEKALSRFEHMQKTRNDLDIITYTIMIHGMCKACMVKEAYDLFYKLKFKRVEPDFKAYTIMIAELNRAGMRTEADALNRFYQKHVRQNESAPAEVS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g26800.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: RABEP_DROME
Sequence: MLDDLPEQFDLVVIGTGFTESCIAAAGSRIGKSVLHLDSNEYYGDVWSSFSMDALCARLDQEVEPHSALRNARYTWHSMEKESETDAQSWNRDSVLAKSRRFSLDLCPRILYAAGELVQLLIKSNICRYAEFRAVDHVCMRHNGEIVSVPCSRSDVFNTKTLTIVEKRLLMKFLTACNDYGEDKCNEDSLEFRGRTFLEYLQAQRVTEKISSCVMQAIAMCGPSTSFEEGMQRTQRFLGSLGRYGNTPFLFPMYGCGELPQCFCRLCAVYGGIYCLKRAVDDIALDSNSNEFLLSSAGKTLRAKNVVSAPGYTPVSKGIELKPHISRGLFISSSPLGNEELNKGGGGVNLLRLLDNEGGREAFLIQLSHYTGACPEGLYIFHLTTPALSEDPASDLAIFTSQLFDQSDAQIIFSSYFTIAAQSSKSPAAEHIYYTDPPTYELDYDAAIANARDIFGKMFPDADFLPRAPDPEEIVVDGEDPSALNEHTLPEDLRAQLHDMQQATQEMDIQE
What is the function of this protein?
Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction.  The component A is thought to be regenerated by transferring its prenylated Rab to a protein acceptor (By similarity).
What are the official names of this protein?
Rab proteins geranylgeranyltransferase component A, Rab escort protein homolog, REP.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle pole. Note=Coordinated with the cell cycle, located around nuclei during prophase and telophase. Located to spindle poles during metaphase.
Protein: Y16C_BPT4
Sequence: MNIKKFQIDGIMNQIQALEYANKMMSTNWGIYTNEPGFQFCDMEFTKKLVGKDYVCPFSSPVNGMLKPALRDLYIAMNEEMIKELKRQLKVIQFGQGN
What are the official names of this protein?
Uncharacterized 11.4 kDa protein in arn-motA intergenic region.
Protein: UBIE_BRADU
Sequence: MDRPGETTHFGFRDVPLGDKQTLVNDVFHSVASRYDLMNDLMSGGLHRVWKDIMINALDPPRGDRPFALLDVAGGTGDISFRAAKAAGPGFHATVCDINSDMLAVGRERAAKRHLETQVDFVEGNAEALAFADRSFDAYTIAFGIRNVPQIDLALREAYRVLRPGSRFLCLEFSTVEMPGLDKLYDLFSFKVIPPLGRMITGDAESYQYLVESIRKFPKPNAFADMIRDAGFARVNWQTLSGGIVALHSGWRL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: MTFA_ECO45
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAERFLQQKRLVPLQGFELNSLRSCRIALLFCLPVLELGLEWLDSFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COL7_CAEEL
Sequence: MSSATFLSVMAGLSGIVVFGALISVFHIYSDINSFVEDSHRELGEFKGFANDAWNSMINQDDSVRMARSVFGRRRQKKQSQCNCGQQASNCPAGPPGPPGASGDKGHDGQPGQAGKPGQPGVAGPSHHQKQECIKCPQGLPGPAGVPGQPGPKGPNGNPGAPAQGGGQGPPGPPGPAGSAGSPGQAGAPGNPGSPGKSGQRGRGLPGPSGAPGPQGPPGAPGQPGSGNAPGPAGPPGPAGPNGQPGHPGQDGQPGAPGNDGTPGSDAAYCPCPTRSSVLRHRNVNRHRAAASKKRVVAKKRVAKKRVVAARRHVQA
What is the function of this protein?
Nematode cuticles are composed largely of collagen-like proteins.  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
What are the official names of this protein?
Cuticle collagen 7.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
Protein: S27A5_RAT
Sequence: MGVWKKLTFLLLSLLLLVGLGQPLWPAATALALRWFLGDPTCFVLLGLAFLGRPWISSWIPHWLSLAAAALTLSLLPPRPPPELRWLHKDVAFAFKLLFYGLNLRRRLNRHPPELFVDALEQQAQARPDQVALVCTGSEGCSITNRELNAKACQAAWALKAKLKEATIQEDKGATAILVLPSKSISALSVFLGLAKLGCPVAWINPHSRGMPLLHSVQSSGASVLIVDPDLQENLEEVLPKLLAENIRCFYLGHSSPTPGVEALGAALDAAPSDPVPAKLRANIKWKSPAIFIYTSGTTGLPKPAILSHERVIQMSNVLSFCGRTADDVVYNVLPLYHSMGLVLGVLGCLQLGATCVLAPKFSASRYWAECRQYSVTVVLYVGEVLRYLCNVPGQPEDKKHTVRFALGNGLRADVWENFQQRFGPIQIWELYGSTEGNVGLMNYVGHCGAVGKTSCFIRMLTPLELVQFDIETAEPVRDKQGFCIPVETGKPGLLLTKIRKNQPFLGYRGSQDETKRKLVANVRQVGDLYYNTGDVLALDQEGFFYFRDRLGDTFRWKGENVSTREVEGVLSILDFLEEVNVYGVTVPGCEGKVGMAAVKLAPGKTFDGQKLYQHVRSWLPAYATPHFIRIQDSLEITNTYKLVKSQLAREGFDVGVIADPLYILDNKAETFRSLMPDVYQAVCEGTWKL
What is the function of this protein?
Mediates the import of long-chain fatty acids (LCFA) by facilitating their transport across cell membranes (By similarity).  Also catalyzes the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (By similarity).  Mainly functions as a bile acyl-CoA synthetase catalyzing the activation of bile acids via formation of bile acid CoA thioesters which is necessary for their subsequent conjugation with glycine or taurine (PubMed:12454267, PubMed:12951368).  In particular, catalyzes the activation of the primary bile acid, chenodeoxycholic acid (PubMed:12454267, PubMed:12951368).  Primary bile acid cholic acid and secondary bile acids (deoxycholic acid and lithocholic acid) are principal substrates too (By similarity).  In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate ((25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate or THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol (By similarity).  Plays an important role in hepatic fatty acid uptake and bile acid reconjugation and recycling but not in de novo synthesis of bile acids (By similarity).
What are the official names of this protein?
Long-chain fatty acid transport protein 5, FATP-5, Fatty acid transport protein 5, Bile acid-CoA ligase, BA-CoA ligase, BAL, Bile acyl-CoA synthetase, BACS, Cholate--CoA ligase, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 5, Very long-chain acyl-CoA synthetase-related protein, VLACS-related, VLACSR.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome. Cell membrane; Multi-pass membrane protein.
Protein: AGAL_SCHPO
Sequence: MISISFLNCFFLVFLFLFFSDVHGSYNGLGLKPQMGWNSWNKYACDIDESIILNNAKAIKEEGLLDLGYEYIVMDDCWSKHERNATTGRLEANPDKFPNGIGSMAKKLHDMGFKFGMYSSAGKYTCAGFPGSLNHEQIDADTFADWGVDYLKYDNCFNEGKSGVPLISYERYKRMSDALNKTGRPIFYSLCQWGEDFVWNWGNTIANSWRISGDIFDTFSRKDVRCPCETIECFALQGDHCSVMNIISKASFLSSKAGMNSGWNDLDSLEVGNGGMSFEEYKTHFTMWAILKSPLILGNDVSSMSPMDKLIVSNKELISINQDIGTNPAALIWKKKYGDEYIELFSGRLSNNDWVVAVLNAASEPLKMGIHLSDIFVDALGNAEHDWLATDLWNNNVKLVSDRIRANVASHGVQVWRFQQYKVKNTNDKFFSFNKH
What is the function of this protein?
Secreted alpha-galactosidase required for catabolic conversion of melibiose to glucose and galactose.
What are the official names of this protein?
Alpha-galactosidase mel1, Alpha-D-galactoside galactohydrolase, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Secreted.
Protein: RL2_SALSV
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLVEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PROB_ALIF1
Sequence: MNTQSQTIVVKLGTSVLTGGTLKLDRAHMVELVRQCVQLKKAGHQVIVVTSGAIAAGREHLNYPELPKTMANKQLLAAVGQSCLIQAWQSLFGIYGVDVGQMLLTRADLDDRERYLNARDMLQALLKNNIVPIVNENDAVATNEIKVGDNDNLSALVGILAGADKLLLLTDQSGLFTADPRKDPKAELIKEVHTIDETLRKIAGGSGTTLGTGGMATKLQAADVARRAGIEVIIAAGSAENVITDVVNSKPQGTKFLPVECALESRKRWILAGPPSKGSIVIDEGAVNAVQQKGSSLLSKGITEVSGHFVRGGVAKIVNTKGELIARGISRYSSDDLSKILGKHSQDIYAVLGYEYGPVAIHRDDLVLI
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_EXISA
Sequence: MAREFSLKNTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNGHRVNIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATTYGVPRVVFVNKMDKIGADFLYSVKTLHDRLQANAYAIQLPIGAEDDFKGIIDLVEMKTYMYNNDLGTDIEVTDGFPADMADQAEELRGQLIEGVADFNEELMMKYLEGEEISIDELKAAIRQATLSVEFYPVLVGSAFKNKGVQLMLNAVVDYLPSPVDVESIKGINLDTEEEITREPSDEAPFSALAFKVMTDPYVGKLTFFRVYSGTAEAGSYVKNSTKGKRERLGRILQMHANSREEIPMVFAGDIAAAVGFKDTTTGDTLCSEKDNIVLESMTFPEPVISVAIEPKSKADQDKMGQALAKLAEEDPTFRTETNPETGQTIISGMGELHLDILVDRMRREFKVEANVGAPQVAYRETIRGAAKIDSKFVRQSGGRGQYGHVVVEFEPNEEGAGFEFENKIVGGVVPREYVPAVQNGIEEALENGILAGYPVVDVKARLVFGSYHDVDSNEMAFKVAASMAVKQLKDQAKAVILEPMMRVEVVIPEEYMGDIMGDVTSRRGRVEGMEARGNAQVVKAMIPLSEMFGYATSLRSRTQGRGTYSMHFDHYEEVPKSIAEEIVKKANG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_THIDA
Sequence: MSTRVVVGLSGGVDSAVAAYLLKQQGYDVLGVFMKNWDDDDNTEHCTARQDFLDVLAVADVLGIEVEAVNFAAEYKERVFSYFLAEYQAGRTPNPDVLCNAEIKFKAFLDDAIARGADYIATGHYVGKGHDTFGRAALLRARDANKDQSYFLYRLNQAQLSPALFPLARLPKPEVREIARRIGLPNAAKKDSTGICFIGERNFREFLERYLPRDPGDMTTPEGRVVGQHQGLMYYTLGQRQGLGIGGQKGGSDAPWFVAAKDMATNTLVVVQGHDHPLLQRFGVGAGQLSWIAGVAPDPERPYTAKTRYRQTDAACHITTLYDDTLELVFDAPQWAVTPGQSVVLYDGDVCLGGGIIC
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSID_SHISS
Sequence: MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAALFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVLGSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGTVSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPALAIFLTVLAFNLLGDGLRDALDPKIKG
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDTH_SALPC
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFIDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCFLSGLGGTLFDPPRSALVVKLIRPEQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAILFILCALFNAWLLPAWKLSTVRTPVREGMRRVMSDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEACLSLTLLYPIARWSEKRFRLEHRLMAGLLVMSLSMIPIGMVGNLQQLFTLICAFYIGSVIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDMGKALTQPELPWMMLGIIGFITFLALGWQFSHKRTPRRMLEPGA
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGK_CLOAB
Sequence: MKFNKKTIEDVDVKGKRVLVRCDFNVPLKDGVITDENRLNGALPTIKYLSEHGGKVILCSHLGKAKGPDPSKTLAPVAKRLSELLGREVKFAADDTVVGENAKKAVAELKEGEIVLLENTRFRPEEGKNDDAFSKDLASLADVYVNDAFGTAHRAHCSTVGVTKFVDTAVCGYLIQKELKFLGSAVENPVRPFVAILGGAKVSDKINVINNLLEKVDTLIIGGGMAYTFLKAQGYTIGTSLLEADKVDYAKEMIEKAEAKGVKLLLPIDNIVGAEFKADTKAVTTEDANIPEGYMGLDIGPKTQKLYADAVKEAKTVVWNGPMGVFEFENFAKGTKDVAKAMAESDATTVIGGGDSAAAVNQLGFGDKMTHISTGGGASLEFLEGKELPGIVALNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2444_BACP2
Sequence: MLLKHFPHDEKPRERFIKYGPSSLSNHELVAILLRTGTKKESVLQISARLLQTFGGLRSVREATIEEMSKIRGVGKAKAISLLAALELGTRLHHQTTDNRYVIRTPEDGANFVMEDMRFLTQENFVCLYLNTKNQVLHKHTVFIGSLNSSIVHPREIFKEAFKRSAASFICVHNHPSGDPTPSREDIEVTQRLFECGKLIGIQLLDHLVIGDQKFVSLKEKGYL
What are the official names of this protein?
UPF0758 protein BPUM_2444.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: SYS2_LACPL
Sequence: MLDVKMIRQNPDFVKEQLGHRGVAASDIDDLLAADEKRRELIAKSEQLKSTRNQVSGEISQKKRNKEDASAEIAEMQKVSADVKTLDEERRTVDAQVQDMAAHLPNMPHPDVPVSLKEEDAVELRRIGTPRHFDFTPKAHWDIGEDLGILDFERGAKVSGSRFLYYVGDGAKLERAVYNFFLDQHEAEGYTEVLPPYMVTDESMYGTGQFPKFKEDAFRITTQDLTLIPTAEVPLVNYYRDEVIPAEKLPVYFTALSPAFREEAGSAGRDTKGLIRLHQFNKVEMVKFTKPEDSWDELEKLTNNAESLLKKLGLPYHVITLTTGDMSFTAAMTHDLEVWFPEQDKYREISSCSNCTDFQARRAHIQYRDDDGKLQFVHTLNGSGLAVGRTVAAILENYQNEDGTVTIPDVLVPYMHGKTKIEKQG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase 2, Seryl-tRNA synthetase 2, SerRS 2, Seryl-tRNA(Ser/Sec) synthetase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.