PharMolix/UniProtQA huggingface dataset:
Protein: CDUB2_CHLT2
Sequence: MEPIHNPPPQTCSYSRPSTTYTSFKDASCDTKVTRIIIALFLIVISCGLILCAYTFRDLLDADYLAQEGPQQATKLLQQLDDVLTGPPLPIWDNEHLFQFSCLMQNKHRRVLPIDICNPLTKFNFLECICNCLMTKQSVNVNETDMCELFCPPTCTPENYRRLLCTSSVFPFVMWHDPSADTQEAMLTKMDQTMSSGRVGNSHWVLVIVDIEYRCVTFFDSLCDYVASPQQMREQLEGLAVSLGAIYPKEGGADSDQEELLSPFQVRIGSTVKVQSPGEFTCGAWCCQFLAWYLENPDFDLEEKVPTNPSERRALLADFISTTEQAMSRYSSLSWPTTD
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protease possesses deubiquitinating and deneddylating activities (By similarity).
What are the official names of this protein?
Deubiquitinase and deneddylase Dub2, ChlaDub2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Secreted. Host cell. Membrane; Single-pass membrane protein. Note=Secreted, and delivered into the host cell.
Protein: PSD_PARL1
Sequence: MDSLTSILTPIHREGHRFAIIFAAVTIVLFLIWNPLGWIGVILTLWCLYFFRDPDRVTPTREGLVVSPADGIVNLITEASPPEELGLGDMVRTRVSIFMNVFNCHVNRAPVAGTVKRVAYRPGLFLNADLDKASDANERNSLLIERADGEQIVVVQIAGLVARRIVCDVREGHDLAAGERFGIIRFGSRLDVYLPVGAIPLVAVGQTAIAGETVLADSISVLPQV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MRC1_SCHPO
Sequence: MASLDENADELHRMDSSDEASINDDQEDILDTPRTRVRKMLASVDMQLSSNAVSEASLDKESTVGNLENQKNRSYSSEIYLHSDTNFLSNFDSAYERVRRLLNQQGGKSSLQKKEVEQIETQEGGDNAKGSPSSENKDSDRNSRLQQLIEKKRNALKKEQEDLIQNSATSHSKSDNLDSESADDSDLADESELSKKYTSDRKIRNASKKALLELHRNTARLTRETALKPEVVVKKKVTLREFFQKIGFKNDNQLENKAISEEEANSTEPPNVEKEEPKPSVDRSTGIVNSEDIKELSVEDDSLELKEITPEALDIGQTSLFTTLNQTQVKKEDNKKFLLKEINAKLNEDDIDSELEIEVKPKTTALDNIEKSKLSEENEHGIKGKLKQLAEIKLSKDGKPFENEFNIKSFNRNLVKRAAVMAKLQRNQLEEELKAKGIYKPTIQGEKEEEEDPLERARNDAEKIRQLEKASGNASDEGELNDEEEVISSSNTPSTKAKTTNKVIISDVIIEATQAEPKRRQKNSRVVFDEEDLTGDSHGSSNMKISESDDESNGDMIRDSFDRLSSESIKDSQKTEELHDSFGINDEVDQSTSLYVQNSQPSASQLTIVDATYSQPPPRWESSSRDDKTNTSSTQPSQVDSLVPTQLDSTIPTQIDSVQRNKDQDDEEILEERRESRRDSKTFLSRTMLYNKDTGKADSAWASDLIEEQAIESDDEYAGIGGLSDDGLSDSDAELEVQNMIDDETTIQKGEVASMAQFAKDQEMDRDEKLVKQLMKDVTTGALRKRNRNGFAALDDSDDEDYSNLRREKLKELRRQKLLEDGNLNVLEGDKRKAFLATVEDSLVSSKDNLTWLDATVEDSGVGSSDLGDEYLYSEQSLNHEEEEQMEEELSEIFSSGGPNVVDRVYLKKSSTRHTSDNNSLEEVLPIFPGVRKLVSNSQSEKIGDLSNDNSMGAKSYKTPIISSTQRPQGRKFRGLMNQSSKADISRTVDAGSIKVVPNSQSANPPRLLASLNNYSDFD
What is the function of this protein?
Component of the replisome and is required for rad3-dependent activation of the checkpoint kinase cds1 in response to replication fork arrest.  Phosphorylation allows it to mediate the activation of cds1.
What are the official names of this protein?
Mediator of replication checkpoint protein 1, DNA replication checkpoint mediator mrc1.
What are the subcellular locations of this protein?
Nucleus. Note=Associated with chromatin.
Protein: NUOB_THERP
Sequence: MGMSAAQSHPNIITTTADWLFSWARRSSLWWLQFGLACCAIEMISSAMPRFDLAERFGMLYRASPRQADLMIVAGTVTKKMAPVVRQLYDQMADPKWVISMGSCANVGGPFDTYAVVQGVDQVIPVDIYVPGCPPVPEALYYGVLELQNRIIRYERLKERYGPEAAEAYREEERQAARSALGPRS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YPE6_NPVLD
Sequence: MSYKLALSGVACLTKSTILRKLEARKYFRVHMLDYKELYDRFDFDLRVGALLHTAYRCTHDRSATVGEYDRVHIFDRLPTESVVYGAIAQGLSEEDGRRAYEKCLEMNLHEDWRSVVLMAAPDTESLVTEKMKRRNNGIDCMNEQYVLAQNKHFKIWSEVMNAPAVEIDWRLDMEAQQTRVINLLHDLVYRWETRENDVLVYYHLLPILRRRYVVCDKGDCPARLREAIDQGSTVVLRWPAGADLEAAKREAVEACKVPLVAVIARDSEWLRSADFERYVVERVLNRAFDC
What are the official names of this protein?
Uncharacterized 33.9 kDa protein in PE 3'region, ORF 6.
Protein: ERR2_HUMAN
Sequence: MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV
What is the function of this protein?
Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcription activity.  Positively regulates ESR1 transcriptional activity upon E2 stimulation.
What are the official names of this protein?
Steroid hormone receptor ERR2, ERR beta-2, Estrogen receptor-like 2, Estrogen-related receptor beta, ERR-beta, Nuclear receptor subfamily 3 group B member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome.
Protein: KAD1_CAEEL
Sequence: MAPTVERKNINLAPLKAAGVPIFFIVGGPGSGKGTQCDKIVAKYGLTHLSSGDLLRDEVKSGSPRGAQLTAIMESGALVPLEVVLDLVKEAMLKAIEKGSKGFLIDGYPREVAQGQQFESEIQEAKLVLFFDVAEETLVKRLLHRAQTSGRADDNADTIKKRLHTFVTSTAPVVDYYESKGKLVRINAEGSVDDIFAVVVANLDKATSKL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase isoenzyme 1, AK 1, ATP-AMP transphosphorylase 1, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_LACDA
Sequence: MSVVSMKQLLEAGVHFGHQTRRWDPKMKPYIFTQRNDIYIIDLQKTIKMLDDAYNYVKAVAQDDGVFLFVGTKKQAQEAIAEEATRAGQYYVNQRWLGGTLTNWTTIQSRVKRLKDLKKMAEDGTFDVLPKKEVSLLTKEMDKLQKFLGGIEDMPRIPDVMFVVDPKKEKIAVHEANKLGIPVVAMVDTNTDPTPIDVIIPSNDDAIRAIRLIAGTMADAVIEGKQGADNADVEKELSESVEENSAEEVDDAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: BYR2_SCHPO
Sequence: MEYYTSKEVAEWLKSIGLEKYIEQFSQNNIEGRHLNHLTLPLLKDLGIENTAKGKQFLKQRDYLREFPRPCILRFIACNGQTRAVQSRGDYQKTLAIALKKFSLEDASKFIVCVSQSSRIKLITEEEFKQICFNSSSPERDRLIIVPKEKPCPSFEDLRRSWEIELAQPAALSSQSSLSPKLSSVLPTSTQKRSVRSNNAKPFESYQRPPSELINSRISDFFPDHQPKLLEKTISNSLRRNLSIRTSQGHNLGNFGQEILPRSSRRARPSELVCPLSSLRISVAEDVNRLPRIDRGFDPPLTVSSTQRISRPPSLQKSITMVGVEPLYQSNGNEKSSKYNVFSESAHGNHQVLSFSPGSSPSFIEQPSPISPTSTTSEDTNTLEEDTDDQSIKWIRGALIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQGSSFWMAPEVVKQTMHTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRIGENILPEFPSNISSSAIDFLEKTFAIDCNLRPTASELLSHPFVS
What is the function of this protein?
Serine/threonine protein kinase involved in conjugation and sporulation (PubMed:2046669, PubMed:1435723).  It is thought that it phosphorylates the byr1 protein kinase which itself phosphorylate the spk1 kinase (PubMed:2046669, PubMed:1435723).
What are the official names of this protein?
Protein kinase byr2, MAPK kinase kinase, MAPKKK, Protein kinase ste8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: DHH1_CRYNH
Sequence: MASSSTLANDDWKQGLAAPPKDLRPQTEDVTATQGSRFEDFGLRRELLMGIYTAGFERPSPIQEQAIPMALTGRDILARAKNGTGKTASFIIPTLNRINTSLSHIQALILVPTRELALQTSQVCKTLGAHIPNLQVMITTGGTTLRDDILRLQQPVHILVGTPGRILDLGSKGIAGLNKCGIFVMDEADKLLSEDFMPVIEQTLALCPQERQVMLFSATFPWTVKEFKDQHMVQPYEINLMDELTLKGVTQYYAYVEESQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKVTELGYSCFYSHAKMQQAHRNRVFHDFRNGMTRNLVCSDLLTRGIDIQAVNVVINFDFPRTAESYLHRIGRSGRFGHLGLAISLLTLEDRHNLYRIESELGTEIAPIPAVIDPVLYVAPAMVEEERESPPPKPAAIAAPPAQQQPQQRQRQHPPVPSHQVAHHSPAAAPIQQQQQQQQQQQQPQYQLAYGQGPPQPQVPFQQANSSPAPAPLPSYPQQAPTQAQGPAQMQSPPSEPATQPQASAQIPVQGQTPPIQPRAQQQGQQQPSQPGQAEGQSQPNRRPNTGGFRGNGRGQGHRGRGRGRGGQPGHPGAGASQSQQAQA
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.  Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs.  May also have a role in translation and mRNA nuclear export (By similarity).  Blocks autophagy in nutrient-rich conditions by, at least partly, binding and repressing the expression of a set of ATG genes, including ATG3, ATG7, ATG8, ATG19, ATG20 and ATG22 (PubMed:26098573).  VAD1-mediated repression of autophagy is regulated by TOR-dependent phosphorylation of the decapping enzyme DCP2 (PubMed:26098573).  Regulates multiple virulence-associated genes (PubMed:15765146).  Repression of autophagy by VAD1 also regulates the pathogenesis (PubMed:26098573).
What are the official names of this protein?
ATP-dependent RNA helicase VAD1, Virulence-associated DEAD box protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: RL29_THESM
Sequence: MKPSEIREMNLEEIEKKIIELRLELAKERGMLTMGTSLENPMVIRDLRRDIARLLTIKKEKLRSKR
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: HXD1_XENTR
Sequence: MNSYLEYTSCGDVVAFSPKFCRSDQRNMTLQPYPGSGADHPFMPVGGVPGSVAHQASHQSPALYAPCSLDVAYEPPPPSDYSFLHSSTDYDYYGSNHLVEETGGHIPYGSSVFPGNGSYILNGQLSYRTLGEETQMAQIAQCKEPLEVYPGGNLQSISPSPGTYPKPASPASDTHVSTFDWMKVKRNPPKKSLQSEYGVASPPCTVRTNFTTKQLTELEKEFHFNKYLTRARRIEIANSLQLNDTQVKIWFQNRRMKQKKREREGSLPNSPPSGPASSICVKTPLSKSVHETATLSPSKDV
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Acts on the anterior body structures.  Acts downstream of meis3 to pattern the hindbrain (By similarity).
What are the official names of this protein?
Homeobox protein Hox-D1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Labial subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1664_ARATH
Sequence: MADTGEVQFMKPFISEKSSKSLEIPLGFNEYFPAPFPITVDLLDYSGRSWTVRMKKRGEKVFLTVGWENFVKDNNLEDGKYLQFIYDRDRTFYVIIYGHNMCSEYRDFPQVAVEVDDYENGEEEEDGDDQDKHQ
What are the official names of this protein?
B3 domain-containing protein At1g16640.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM1_SALTO
Sequence: MKLLVVGASYRTAPVAALERLTVAPADLSRVLTRLVAQPYVSEAVLVSTCNRVEVYAVVSGFHGGLGDICAVLAESTGCQPAALADHLYVHFDAAAVNHVFRVAVGLDSMVVGEAQILGQLRDAYHWASEAETVGRLLHELMQQALRVGKRAHSETGIDRAGQSVVTAALGLATELLHSDLACRPALVVGAGAMGSLGVATLARLGAGPVSVTNRGVDRAIRLAESYGATAVPIADLTATLSTVDIVVAATAAPEAVLTRAVVTQALAGRNPSRGPLVLLDLAVPRDVEPGVADLPGVQVIDIDRMAALVADGPVAADAAAVEQIVAAEVDTFLTWLRGADVAPTVAALRGRADDVVAAELGRLVHRRPDLTDEQRADVARTVHRVVQRLLHQPTVRVRQLAAEPGGDQYTALLRELFDLEVPQTSAVGTVPDVVVPDVDPQLGGDAEAPPTGGE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: LFTR_RHIL3
Sequence: MAGSRRKSPGITPDILLRAYSIGLFPMAESADDPEIFWVEPELRGVLPFDHFHVSKSLAKTVRKKPFEIRFDHAFDQVIAACAEETSGRPSTWINRTIRSLYSTLFDMGHAHTVEAWEGNELVGGLYGVSLGSAFFGESMFSRRTDASKICLVHLVDRLRERGFTLLDTQFTTEHLKTFGAIDVPKADYAAMLTAAMESPHLKF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIZ_SHIDS
Sequence: MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVAESTPDIPKAPWEI
What are the official names of this protein?
UPF0509 protein YciZ.
What is the protein family that this protein belongs to?
Belongs to the UPF0509 family.
Protein: RECF_ARTS2
Sequence: MYLEKLSLTDFRSYAQVDLTLEPGVTVLVGYNGIGKTNLMEAIGYLATLSSHRVSSDAPLLRFGTERALIRAKLVRGGQSTVLELEINGSRANRGRINRSNPVRARDILGICQTVLFAPEDLALVKGDPSNRRRFLDELLVSLMPRHSATRTDYDRVLKQRNALLKSGRSGKFTAGHEATLDVWDQHMARAGAELLYARLELVERIRPHLKAAYAQLTDGSKEADAIYRSTLQGILDDDGAGAGYAAEPAAVERVEDLRALSVEELTQRYVQAFAASRRKELERGISLVGPHRDDVELILGEAPAKGYASHGETWSMCLSLRLASYYVMLDDARTGGSAPILILDDVFAELDVQRRRKLAAIVSGAEQVLVTAAVDADIPDELAGRRVKVVPGGIDESESR
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECOT_ECOLC
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: P0_PLRV1
Sequence: MIVLTQSGTLLFDQRFKLSKFLFVVIATGFPLLLQQASLIYGYNHEQIYRICRSFLHVLPLLNCKRGRISTSGLQLPRHLHYECLEWGLLCGTHPAIQIVGLTIVIKLDDPTTAAAYRSELLRVSSSSYIQNAAGLSNGWGHDMEAFVRNAICLLELRERSIPQSGLRDLMGNYQHLVRSLLDACKVDHFVPLDFQHRSLMLNFARLYNQLDLQGRAKSFRALTGFPVYVPSEDYLEGSFLQKELQE
What is the function of this protein?
Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (PubMed:24450775, PubMed:30791535).  The P0 protein suppresses local PTGS using its F-box-like domain to mediate destabilization and degradation of the AGO1 protein, although not via an interaction with host SKP1A (PubMed:24450775).  Participates, together with the proteins P1 and P7, in the inhibition of the induction of aphid-induced host phytohormones (PubMed:31758809).  This could play a role in the attraction to the infected plants by aphids (PubMed:31758809).
What are the official names of this protein?
Suppressor of silencing P0, 28 kDa protein, Protein ORF0.
What is the protein family that this protein belongs to?
Belongs to the polerovirus P0 protein family.
Protein: TP8L1_DANRE
Sequence: MDSFSTKNLALQAQKKLMSKMATKTVANLFIDDTSSEVLDELYRVTKEYTRNRKEAQKIIKNLIKMVVKLGVLYRNGQFNNEELALVERFRKKVHTLAMTAVSFYQIDFTFDRRVMSNLLNDCRELLHQAINRHLTAKSHARINHVFNHFADCDFLATLYGPSEVYRGHLQKICEGVNKMLDEGNL
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8-like protein 1, TIPE1, TNF alpha-induced protein 8-like protein 1, TNFAIP8-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMC4_MOUSE
Sequence: MRRKGTKPSTACHQEEGPPPSQDGAHSDEEMEQPAGEAESAAPAKPPGEELDNRSLEEILNSIPPPPPPAMASEAGAPRLMITHIVNQNFKSYAGEKVLGPFHKRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKIRSKKLSVLIHNSDEHKDIQSCTVEVHFQKIIDKEGDDYEVLPNSNFYVSRTAYRDSTSVYHISGKKKTFKDVGNLLRSHGIDLDHNRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNEPIKVLCRRVEILNEHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEMFKKKNHICQYYIYDLQNRIAEITTQKEKIHEDTKEITEKSNVLSNEMKAKNSAVKDVEKKLNKVTKFIEQNKEKFTQLDLEDVQVREKLKHATSKAKKLEKQLQKDKEKVEELKSVPAKSKTVINETTTRNNSLEKEREKEEKKLKEVMDSLKQETQGLQKEKEIQEKELMGFNKSVNEARSKMEVAQSELDIYLSRHNTAVSQLSKAKEALITASETLKERKAAIKDINTKLPQTQQELKEKEKELQKLTQEEINLKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRLGDLGAIDEKYDIAISSCCHALDYIVVDSIDTAQECVNFLKKHNIGIATFIGLDKMTVWAKKMSKIQTPENTPRLFDLVKVKNEEIRQAFYFALRDTLVANNLDQATRVAYQRDRRWRVVTLQGQIIEQSGTMSGGGSKVMRGRMGSSVIDEISVEEVNKMESQLERHSKQAMQIQEQKVQHEEAVVKLRHSERDMRNTLEKFAASIQGLSEQEEYLCVQIKELEANVLTTAPDRKQQKLLEENVSVFKKEYDAVAEKAGKVEAEIKRLHNTIIDINNRKLKAQQNKLDTINKQLDECASAITKAQVAIKTADRNLKKAQDSVCRTEKEIKDTEKEINDLKTELKNIEDKAEEVINNTKTAETSLPEIQKEHRNLLQELKVIQENEHALQKDALSIKLKLEQIDGHISEHNSKIKYWQKEISKIKLHPVEDNPVETVAVLSQEELEAIKNPESITNEIALLEAQCREMKPNLGAIAEYKKKEDLYLQRVAELDKITSERDNFRQAYEDLRKQRLNEFMAGFYVITNKLKENYQMLTLGGDAELELVDSLDPFSEGIMFSVRPPKKSWKKIFNLSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNVSIVAFYIYEQTKNAQFIIISLRNNMFEISDRLIGIYKTYNSTKSVAVNPKQIASKGLC
What is the function of this protein?
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).
What are the official names of this protein?
Structural maintenance of chromosomes protein 4, SMC protein 4, SMC-4, Chromosome-associated polypeptide C, XCAP-C homolog.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDC2, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase (By similarity).
Protein: SYI_LACCB
Sequence: MKIKDTLNMGKTSFPMRAGLPKNEPIWQKKWDEDHVYEQRQKLNEGKPTFMLHDGPPFANGNIHMGHALNKISKDIIVRYKSMNGFRAPYVPGWDTHGLPIEQQLAKQGVKRKEMSMTDYRELCRQFAMQEIDKQRTDFKRLGVMGDWEHPYITLQHHYEASEIRVFGAMAKKGYIYHGLKPVYWSWSSESTLAEAEIEYHDDKSPSIYVAFKVVDGKGLLDTDTYLVIWTTTPWTIPANYGITVNPRFDYVQVQVGDKKYVVAAELLDRVAEEIGWENPKILKTFKGTDMDKMTAQHPLYDRTSLVMNADHVTLDAGTGLVHTAPGHGEDDYKVGVKYGLPVVSVVDAKGYMNEYAPGFEGVFYDDANKQITQALADKGALLKLDFFTHSYPHDWRTKKPVIFRATTQWFASIDAFRDQILKAIDTVDFKPSWGKTRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGEPIIEEETINHVADLFGKYGSNVWFEREAKDLLPEGYTNPHSPNGQFTKEKDIMDVWFDSGSSHQAVLAARPELSFPADLYLEGSDQYRGWFNSSLITSVAATGVAPYRGILSQGFTLDGKGRKMSKSLGNTIVPATIEKQFGAEIIRLWVATVDSSSDVRVSVDNFAQTSEAYRKIRNTMRFMVANTGDFDPEKDTVAYDELGSVDRYMMVRLNQIIKQVKTAYDAYDFATVEKTISSFLVNDLSAFYLDVAKDVVYIEAKDDPKRRGMQTVMFAALLTVTKLITPILPHTAEEVWPYLKQPEAYAALADMPEAEQFDDESQLLDIWSGFMDFRSEVQKALELARDNKVIGKSLEAAVTVYPSEPVRDMLDDVDANVMQLLITSHFEIAPATTKAPADAEQFDDMAVVVKHADGEVCPRCRMVRTDIGTDPKLPQLCSRCAAIVEANFPDAVTNGFDK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_BACAA
Sequence: MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFMQEQLFDHLPFKQTYVPNGMASDLEEECKRYEGILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLRFFEKEEDVPTHAITMGIGSIMKAKQILLVAMGSKKAEAVKELLQGAYSEACPATVLQRHPNVTVIADQEALSLCSEAIADEHRQVFTISDLLSDSRVGETAN
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: THT10_TOBAC
Sequence: MATTNNKNLTITEKVYVRVRLANEADISHIYKLFYQIHEYHNYTHLYKATESSLCDLLFKANPNPLFYGPSVLLLEVSPTPFENTKKDEKFKPVLKTFDLRATVEDKEAEEFKSKSCGDEKEDVFIAGYAFFYANYSCFYDKAGIYFESLYFRESYRKLGMGGLLFGTVASIAANNGFASVEGIVAVWNKKSYDFYVNMGVEIFDEFRYGKLVGDALQKYADKEKV
What is the function of this protein?
Synthesizes amides which are involved in stress response in the cell wall.  Catalyzes the synthesis of hydroxycinnamic acid amides from hydroxycinnamoyl-CoA thioesters and various hydroxyphenylethylamines such as 4-coumaroyl-CoA and sinapoyl-CoA.
What are the official names of this protein?
Tyramine N-feruloyltransferase 10/30, Hydroxycinnamoyl-CoA: tyramine N-hydroxycinnamoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_THET8
Sequence: MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAARVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPGRVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ
What is the function of this protein?
This protein binds directly to 23S rRNA.  Interacts with the A site tRNA.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.