PharMolix/UniProtQA huggingface dataset:
Protein: COXX_BRUSI
Sequence: MSLVEKNTASEDAFALSEATARDYLVLLKPRVMSLVVFTGLVGLVLAPGHMNPVLAVISILCIAVGAGASGALNMWYDADIDAVMKRTRKRPIPAGIIAPNQVLAFGLTLSAFSVMTLGLMVNWLAAALLAFTIFFYAVIYTMWLKRSTPQNIVIGGAAGAFPPMIGWAAATGEITWDSLVLFMIIFLWTPPHFWALSLFTTNDYEAARIPMMPNVKGELSTRRQALFYAVLMAPVGVLPWVMGFAGMFYGVVSTLLGLAFVYYAWRLWAADSQLQMLAAARKLFRFSLLYLAGIFAVLLFEALTFKLLAAFGVF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RFAY_ECOLX
Sequence: MITSIRYRGFSFYYKDNDNKYKEIFDEILAYNFKTVKVLRNIDDTKVSLIDTKYGRYVFKVFAPKTKRNERFLKSFVKGDYYQNLIVETDRVRSAGLTFPNDFYFLAERKIFNYASVFIMLIEYVEGVELNDMPIIPENVKAEIKASMEKLHALNMLSGDPHRGNFIVSKDGVRIIDLSGKSCTAERKARDRLAMERHLGIANEIKDYGYYSVIYRTKLRKFIKKLKGKA
What is the function of this protein?
Catalyzes the phosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II) kinase RfaY.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. RfaY/WaaY family.
Protein: YDU2_SCHPO
Sequence: MEPGSKLSEDETFSQTFNEEEQEDSRNKDILAFDPSVDNEPLLTKKLSSLSIYSEPSPDEASNLQELKFVSSPPSVRVPRSRRNRRNSRVDSEARKRQFDRVKHSVSNSCKLHLSLQGQEAAQLRSDSLYLEASDKRDLTSLVTRVKELARKLSAARLAFRFRKVLLICNDNKESIERSVELAQWLLDTFSFTPSSSHNNMASSNTQSNTQLSEMESEEKSFNKDVYPNDEYTPFTPKNQFVIYLEDTLASLDVVESLSPKKNVRFWTSELCTQCPNLFDCVITVGDDSAALRASWLFQDVVPPVLSFSTAKAGFLSILPIAEYTKTLDLIFHRGFTVNLRMRFQCSIMRYVGEHSTHICEGQYSVLNELLIDRGPNPFMISLDLYVENEYITTLQSDGVCVSTPTGSTAYSVAAGGSLCHPGIPAILISAICPHSLSFRPIILPDSMTLRIVVPLDARSNAWCAFDGHHRIELGLGDYISISASSFPFPSVIRSKYSKDWFDILRQTLNWNDRKGRQRSSRYKSHVHKTNTSEEQN
What are the official names of this protein?
Uncharacterized kinase C1B1.02c.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
Protein: LEUC_NITEU
Sequence: MKTLYDKLWSDHVVHAESDDPNGMVILYIDRHLVHEVTSPQAFESLKLAGRKPWRTGSILAVADHNVPTTDRSSGISDPVSRLQVETLDQNCEEFAITEFRMNDERQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFACLAFGIGTSEVEHVLATQCLVARKSKTMLVRVEGDLPPGVTAKDIALAVIGEIGTAGGTGYAIEFAGSAIRSLSMEGRMTLCNMAIEAGARAGMVGADEVTIDYIKGRPFAPQGALWDQAVAYWRTLKSDEDAVFDRMVELKAVNIKPQVTWGTSPEMVTTVDGYVPDPADISDPTKRHDVEHALGYMGLKPKMPIQEITLDKVFIGSCTNSRIEDLRAAAEIVKGKRIAPNIRLAMVVPGSGLVKSMAEKEGLDKIFLSAGFEWREPGCSMCLAMNDDRLLPGERCASTSNRNFEGRQGPGGRTHLVSPAMAAAAAIAGHFVDVRSFIR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PA2D6_MICPY
Sequence: NLNQFSNMIQCANTRSXLXFANYGCYCGY
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 D6, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VG03_BPML5
Sequence: MAQMQATHTIEGFLAVEVAPRAFVAENGHVLTRLSATKWGGGEGLEILNYEGPGTVEVSDEKLAEAQRASEVEAELRREVGKE
What are the official names of this protein?
Gene 3 protein, Gp3.
Protein: PGK_CUTAK
Sequence: MKSVEDLGDLRGKRVVIRCDFNVPLDGDKITDDGRIKAALPTLTQLHEAGARTTVLAHLGRPKGAVDPKYSLAPVAKRLGELMNLDVKLAGDVVGPSATKTSESLADGEIALVENVRFEKGETSKDEAERAELAQKYASFGEFYVSNGFGVVHRKQASVYDVAKLLPSAAGSLVAKEVEVLEGLTADPKRPFVVVLGGAKVADKLAVIDNLLKAADTLVIGGGMAYTFLKAKGLEVGDSLLDEDSIDACTKYLEQAKAAGKQILLPVDVRVVSDIDFEARTVGQIDVVPADEIPSDKMAVDIGPETEKAYANAIKGAKSVFWNGPMGVFEIKGLELGTKAVAQALTEVDGLSVVGGGDSASAVRTLGFADDQFGHISTGGGASLELMEGKELPGIAVLKENN
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPA_PECCP
Sequence: MRNPDFSPLYRSAIGFDRLFNLLETGQTQSNGGYPPYNVELVDENQYRIAIAVAGFAEQELDITAHDNLLIVKGAHAGEQVARNYLYQGIAERNFERKFQLAEHIQVKGANLENGLLYIDLERIVPEAMKPRRIEIK
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_STAES
Sequence: MKCIVGLGNIGKRFELTRHNIGFEVVDDILERHQFTLDKQKFKGAYTIERLNGEKVLFIEPMTMMNLSGQAVAPLMDYYNVDVEDLIVLYDDLDLEQGQVRLRQKGSAGGHNGMKSIIKMLGTDQFKRIRIGVGRPTNGMSVPDYVLQKFSKEEMIIMEKVIEHSARAVESFIESSRFDHVMNEFNGEVK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RATA_VIBC3
Sequence: MKQVSRSALVSFSAEQMFHLVNDVARYPEFLPGCSGSCVLEQSEAHMVASVDVSKAGISKTFTTSNQLTPGVSIAMSLVDGPFKTLRGGWFFTPLDEAACKVELRLEFEFSSKMIELAFGKIFNELTSNMVNAFTRRAKQVYGE
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Binds to 50S ribosomal subunits, preventing them from associating with 30S subunits to form 70S ribosomes.  Its antitoxin is unknown (By similarity).
What are the official names of this protein?
Ribosome association toxin RatA.
What is the protein family that this protein belongs to?
Belongs to the ribosome association toxin RatA family.
Protein: NBL1_XENTR
Sequence: MTVWLLIGFLLPVAIFAAPPINRLALFPDKSAWCEAKNITQIVGHSGCESKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPIDSVWDVVTLECPGNEEFPRVDKLVEKILQCSCQACGKELSQEGAMFNVYLNTAEETLSPAETLGHHHHRPPAREEDSPAQSQREGESEE
What is the function of this protein?
May act as a tumor suppressor.  Cytokine that has an axial patterning activity.  Acts like bone morpho-genetic protein (BMP) antagonist in embryonic explants.  Blocks the bmp2 activity (By similarity).
What are the official names of this protein?
Neuroblastoma suppressor of tumorigenicity 1.
What is the protein family that this protein belongs to?
Belongs to the DAN family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPMI_ACHLI
Sequence: MKEKFAALIIMDGLGIAPASDSNSVTLADTTYLDNLLKEYPNSTLVTSGEAVGLPEGQMGNSEVGHLNLGAGRIVWQSLSRINVAIKDGSFFKNQAFLDAVAHAKKHNSKLHIMGLVSDGGVHAQMGHYLALYDFAKQQNILDRTYLHVFTDGRDTPQESGYGFVKTLVDYGFNVATVSGRFYAMDRDNNWDRVQLAFDAMTLGDGPHFNSALDGIESSYKSGIQDEFIKPFIVNDKGLIENDDAVIFANFRPDRAIRIATALSNPSAAKTIYTEGKPMLNVSKAPKNIFLVSMMHYKETVKGPLAFELQTFDDLYGEVIEKNGFKQIRAAETEKYPHVTFFFDGGKEVPLANSTRILAESPKVPTYDLKPEMSAYELTDKVIAALKTGEYQTMILNFANPDMVGHTGNIEATKKAVEVTVECVGKVTDFIINELGGVAIILADHGNAEQMRDQEGKPHTAHTTNLVPVVVTKKGIKLNSGALCDVAPTLLDLLGIEKPKAMTGTSLIEKI
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RECO_LEVBA
Sequence: MARNVTDFHGILLFRRDYAERDFLIKFFTQEFGKKMFLVRGAKKRGFKMVADILPFTVGSYVGDIADDGLSYIRTARETRQFQDISADIFKNAYATYIMSLVDTAFPDSQPLPDWYHRVQRALTLIDDGVNAAIVTNIMEIQLMPAFGVAPQLQGCAVCGRNDLPFDYSESYGGLLCQAHWTLDPRRLHVSQRTIYYLRQFSVLDLDRLHTIKVKPQTEHALRQLMDEIYDSQIGVHPKSKRFLDQMQSWSARLKPPTDH
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SFT2_YEAST
Sequence: MSEEPPSDQVNSLRDSLNRWNQTRQQNSQGFNESAKTLFSSWADSLNTRAQDIYQTLPVSRQDLVQDQEPSWFQLSRTERMVLFVCFLLGATACFTLCTFLFPVLAAKPRKFGLLWTMGSLLFVLAFGVLMGPLAYLKHLTARERLPFSMFFFATCFMTIYFAAFSKNTVLTITCALLELVAVIYYAISYFPFGATGLRMLSSAGVNSARGVLRI
What is the function of this protein?
Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.  Can be partially replaced by GOT1.
What are the official names of this protein?
Protein transport protein SFT2.
What is the protein family that this protein belongs to?
Belongs to the SFT2 family.
Protein: LIGB_SHIFL
Sequence: MKVWMAILISILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQWDDDYWKEGKSEVEDGVYDQLSARLTQWQRCFVSEPRDVMMPPLNGAVMHPVAHTGVRKMADKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSLISAVLQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQGNSDTLNSLAVFVWAWPDGPQLMTDRLKELATAGFTLTQRYTRAVKNADEVARVRNEWWKAKLPFVTDGVVVRGAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTPPENRFNPLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTPGIAKSKSAQLWHQFNLARNQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: PHOP_SALCH
Sequence: MMRVLVVEDNALLRHHLKVQLQDSGHQVDATEDAREADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSSDISLPVLVLTAREGWQDKVEVLSSGADDYVTKPFHIEEVMARMQALMRRNSGLASQVINIPPFQVDLSRRELSVNEEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPHDVITTVRGQGYLFELR
What is the function of this protein?
Member of the two-component regulatory system PhoQ/PhoP which regulates the expression of genes involved in virulence and resistance to host defense antimicrobial peptides.
What are the official names of this protein?
Virulence transcriptional regulatory protein PhoP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_STAAW
Sequence: MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSP1_HORVU
Sequence: MGLLSKKLLVASMVAAVLAVAAVELCSAIPMEDKDLESEEALWDLYERWQSAHRVRRHHAEKHRRFGTFKSNAHFIHSHNKRGDHPYRLHLNRFGDMDQAEFRATFVGDLRRDTPAKPPSVPGFMYAALNVSDLPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCDTADNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHIDGHQDVPANSEEDLARAVANQPVSVAVEASGKAFMFYSEGVFTGDCGTELDHGVAVVGYGVAEDGKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPVKTYNKPMPRRALGAWESQ
What are the official names of this protein?
Cysteine proteinase EP-B 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: ENGB_RICCN
Sequence: MTTQKIVPTKSTDGSKLFRHQAKFVAGAMNINQILNFSLPEIAFVGKSNVGKSSLINTICNNKNLAKVSNTPGRTRQINFFNLADKLIIVDLPGYGFANVPISVKEQWGVLISYYLRNSYNLRLVNLLIDSRRGIKENDKKVADLLLANKREFQIIFTKSDKVTDHKNLHDEAQNFLATLNYSCNVMYVSNRSKEGARELKASLAKCIKPQK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RSGA_LACLA
Sequence: MIKNGRIVKSLAGFYDVESEGEVYQTRARGNFRKKGMKPVVGDFVEFSTEENSEGYILKIGERKNSLIRPSIANIDQAVIIMSTVSPNFSLNLLDRFLVFLEHKNIHPMIYISKLDLLTEMQEGSDKNKKTFNQLTDYEQIKSDYEQIGYDVFFDAEHLVSNLAGKVTVFMGQTGAGKTTLLNKIAPEMQLATGETSEKLGRGRHTTRHVEFFELAGGLIADTPGFSSLDYEVTNRPDLNAAFPEILRISHDCKFRECTHTHEPSCAVKLALENHEILESRYDNYLQILDEINHTRETYEKKRKKQG
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_ALKCK
Sequence: MPRKGPVARRDVLPDPIYNSKLVTRLINRIMVDGKRGTAQTILYNAFELVKERSGNDPMEVFDQALKNIMPVLEVKARRVGGSNYQVPIEVKPERRTTLGLRWLVNYARLRGEKTMEERLANEILDAANNAGAAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: THIL_METHJ
Sequence: MDDRDLLEIIRPVCGSDTCSDDCAILTLPCGALVTSTDMLHERSDFPAGMTGWQIGWMSVAVTISDIAAMGAEPLQIVLAIGLDTEERLAEIVLGAQACCDTYGAVYAGGDLDAHSELTIVSTGVGIIRDGEPVRRGGAKPGDIICVTGTLGRAILGLTGDSRFWKDLCEPQPRVREGTVARLAGAHAMMDISDGLAISLYDIAAESHVGMEISSGRIPLPPEADVQVALEAALYGGGDFELLFFISEEKMKNLTIPVTQIGRVSEGLKITMDGMELPKKGYLHHW
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.
Protein: QUEF_PARP8
Sequence: MTPEQSPLGKPSSYTEQYDASLLFPIARKNARDQIGIGATLPFFGTDIWNAYELSWLNARGKPQIAIATFYVPADSPNIVESKSFKLYLGSFAQSSFDSIDVVRDTIKRDVSAACGSSVSLHLYPPAEFSKLGLEEFEGTSLDRLDLDAEVYQPDASILKAALDEAPVEETLFSNLLKSNCPVTGQPDWGSVQIHYVGPQIDHAALLRYIISYRNHTGFHEQCVEKIFLDVMKVCQPVKLAVYARYTRRGGLDINPFRTNFNLPMPDNLRTARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPAT_MARSD
Sequence: MPEFKLADRLATLPPYLFAEIDRLKAEVAAQGVDIISLGIGDPDLPTPDFIIEALHKAAKNPVNHQYPSYVGLLTFRQAVADWYKERFDVELDATKEVVSLIGSKEGIAHFPLAFVNPGDLVLVASPNYPVYPVASGFAGGEVEIVPLLEENDFLPNLDAISDEKWDKCKIFFVNYPNNPTSATATPEFYAELVAKAKKHNVIIAADAAYTEVYYDEDKKPISILETPGAKDVAIEFHSLSKTYNMTGWRCGMAVGNASLVAGLGKIKENVDSGIFQAVQEAGIVALKEGEPYVKEFRKIYKERRDCVIEALEKINISCKVPDASIFVWAKTPEGYTSSEFVSKLLKETGVVVTPGNGFGESGEGYFRISLTVDTDRLKEAVSRISKL
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: UACF_ECOLI
Sequence: MNKFIAAEAAECIGCHACEIACAVAHNQENWPLSHSDFRPRIHVVGKGQAANPVACHHCNNAPCVTACPVNALTFQSDSVQLDEQKCIGCKRCAIACPFGVVEMVDTIAQKCDLCNQRSSGTQACIEVCPTQALRLMDDKGLQQIKVARQRKTAAGKASSDAQPSRSAALLPVNSRKGADKISASERKTHFGEIYCGLDPQQATYESDRCVYCAEKANCNWHCPLHNAIPDYIRLVQEGKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKDHSGAVSIGNLERYITDTALAMGWRPDVSKVVPRSEKVAVIGAGPAGLGCADILARAGVQVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDITFSDLTSEYDAVFIGVGTYGMMRADLPHEDAPGVIQALPFLTAHTRQLMGLPESEEYPLTDVEGKRVVVLGGGDTTMDCLRTSIRLNAASVTCAYRRDEVSMPGSRKEVVNAREEGVEFQFNVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADVLIMAFGFQAHAMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGRQAARDMLTLFDTKAS
What is the function of this protein?
Involved in formate-dependent uric acid degradation under microaerobic and anaerobic conditions.  May reduce the enzymes necessary for uric acid degradation.
What are the official names of this protein?
Putative oxidoreductase UacF, Uric acid degradation formate-related element.
Protein: DTD_BACC0
Sequence: MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUSD4_XENTR
Sequence: MAAAGGGATRGARMLAERIRAERKVLEGAARETSRKNAPTIVYLRELKSQVVREDPELVLVNKPHGLPVHGGPTVERSVASLLPALAKHHFGWKAEPLKLCHRLDRDTTGALILARTTEAAERVQQALREREVHRVYWALCLGTPSPREGILDIPIMEKETSGPQKHYKMALSPRFRVSEEGAVERVRVPRSAHEAVTRYRTLGAASGASLVELHPITGVKHQLRVHLALGLNCPILGDHKYSHWGRLAPQKPPDSVLRALGLTVPQARTLSLHLHAVQLTLPSSDGSTPIVLQCPLPYTFRKTLRKLRIPPPDLESLQPPPTD
What is the function of this protein?
Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates.  Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA).  This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome.  Acts on position 39 in mitochondrial tRNA(Phe).  Also catalyzes pseudouridylation of mRNAs in nucleus: acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions.  Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing.
What are the official names of this protein?
Pseudouridylate synthase RPUSD4, mitochondrial, RNA pseudouridylate synthase domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Mainly localizes to mitochondrion. Localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly. Also found in nucleus and cytoplasm.
Protein: TBC19_HUMAN
Sequence: MLQEESDLSLIIAQIVQKLKGSNLYSQLERQAWASLQRPEIKLESLKEDIKEFFKISGWEKKLQNAVYSELSVFPLPSHPAAPPEHLKEPLVYMRKAQGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLINLRNPNYENGDSLSFRTHLGLIQVPLKVKDIPELKECFVELGLNIGQLGIDDSTQVPPELFENEHVRIGQKVLAEQDSAAAQQYIRQGSPTALRAELWALILNISSQPEDVLYYEQLKTNVIQHDLLVDSLIYKDVKLTASNDDYYFVFEDYLYQVLLCFSRDTSVLSHFAFNSASPPKSYIRGKLGLEEYAVFYPPNGVIPFHGFSMYVAPLCFLYHEPSKLYQIFREMYVRFFFRLHSISSHPSGIVSLCLLFETLLQTYLPQLFYHLREIGAQPLRISFKWMVRAFSGYLATDQLLLLWDRILGYNSLEILAVLAAAVFAFRAVNLMEVTSLAAAEAVLADLSTLKVMPLLQIFLFATVT
What is the function of this protein?
May act as a GTPase-activating protein for Rab family protein(s).
What are the official names of this protein?
TBC1 domain family member 19.
Protein: CDNTP_ASPFM
Sequence: MDGEMTASPPDISACDTSAVDEQTGQSGQSQAPIPKDIAYHTLTKALLFPDIDQYQHWHHVAPMLAKMLVDGKYSIHQQYEYLCLFAQLVAPVLGPYPSPGRDVYRCTLGGNMTVELSQNFQRSGSTTRIAFEPVRYQASVGHDRFNRTSVNAFFSQLQLLVKSVNIELHHLLSEHLTLTAKDERNLNEEQLTKYLTNFQVKTQYVVALDLRKTGIVAKEYFFPGIKCAATGQTGSNACFGAIRAVDKDGHLDSLCQLIEAHFQQSKIDDAFLCCDLVDPAHTRFKVYIADPLVTLARAEEHWTLGGRLTDEDAAVGLEIIRGLWSELGIIQGPLEPSAMMEKGLLPIMLNYEMKAGQRLPKPKLYMPLTGIPETKIARIMTAFFQRHDMPEQAEVFMENLQAYYEGKNLEEATRYQAWLSFAYTKEKGPYLSIYYFWPE
What is the function of this protein?
Prenyltransferase that catalyzes reverse prenylation at position N-1 of tryptophan-containing cyclic dipeptides (PubMed:17525915, PubMed:35767141, PubMed:18383240, PubMed:19113967, PubMed:19421461, PubMed:33643664).  Accepts only dimethylallyl diphosphate (DMAPP) as the prenyl donor but shows broad substrate specificities toward its aromatic substrates (PubMed:17525915, PubMed:18383240, PubMed:19113967, PubMed:19421461, PubMed:33643664, PubMed:35767141).  Shows also tryptophan aminopeptidase activity with preference for linear peptides containing a tryptophanyl moiety at the N-terminus (PubMed:18635009).
What are the official names of this protein?
Cyclic dipeptide prenyltransferase, CdpNPT, Tryptophan aminopeptidase CdpNPT.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: OEP36_ARATH
Sequence: MFHGIKGCMIPMYWWLLGDLDLNGVRNSASSYSGGVNLSKLAVGLDLSEPASSKWSSTTSVKFEVPGHYLLQTLYMCVRLTMTDGRYQRSGRISYNMQNSLLCSGNTHDSMVVLKQESRFAKATDQGLSHFSMQIEQGIPVVSNWLIFNRFKFVASKGVRFGPAFPLASLTGGSIVGDMTPYQAFAIGGLGSVRGYGEVAVGSGRSCLVANTELANKMTEGTIFLDCGTDLGSSRLVPVSSLYLLRTRTIKKLLRHENDKAVAELVSGNPSLRQGKPGFGYGFGYGLRFKSPLGHLQVDYAMNAFNQKTLYFGITNLASST
What is the function of this protein?
May play a role during plastid development.
What are the official names of this protein?
Outer envelope protein 36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the OEP80 (TC 1.B.33.2) family.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane.