PharMolix/UniProtQA huggingface dataset:
Protein: PROA_BURCM
Sequence: MDIDQYMTDLGRRARHASRAMARASTAAKNAALDAVARAIERDAQALKDANARDVARAREKGLDAAFIDRLTLSDNALKTMVEGLRQVASLADPIGEIGNLKYRPSGIQVGQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNATILRGGSEALESNAALAKLIGEGLEAAGLPQDAVQVVATADRAAVGKLITMTDYVDVIVPRGGKSLIERLINEARVPMIKHLDGICHVYVDDRADLAKALTVCDNAKTHRYGTCNTMETLLVASGIAATLLPPLGKLYRDKQVELRVDAAARAVLAEAGVGPLVDATDEDWHTEYLAPVLAIKVVDGLDAAIEHINHYGSHHTDAIVTEDHDRAMRFLREVDSASVMVNASTRFADGFEFGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGHGEGRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_SINMW
Sequence: MSVHTTKRRLSPASIESLKGDRPIVSLTAYTTPIARLLDPHVDFLLVGDSLGMVLYGLDTTVGVTLDMMIAHGQAVMRGSERCCVVVDLPFGAYQESKEQAFRSAARILKETGCSAVKLEGGAEMAETVEFLVSRGIPVLGHVGLMPQLVNTTGGYRSVGRNEKEVAKIRRDAKAIDDAGAFAIVVEGTVEPVAREITATLRAPTIGIGASPACDGQILVSDDMLGLFNDFKPRFVKHFAELAPAISKAVEDYANEVKARTFPGIEHTFQVKR
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_MYCSS
Sequence: MTDISKVIASLMREVPDFPEPGIQFKDLTPLLADAEGLMAVTDALAATAEGADLVAGIDARGFLLGAAVALRLGTGVLAVRKGGKLPPPVHSQTYNLEYGSATLEIPADGLDIAGRSVVIIDDVLATGGTVAATHRLLTSGGATVLHAAVVLELTALGGREVVQPLSVSSLYTV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SHESH
Sequence: MDKIKIALQYMMPKHLISRLVGKLAAAELGSITTAAIKWFIKQYKIDMSEAAQSEPEAYTTFNNFFTRALKPGIRPLFDDKDYIVHPVDGAISQCGPIKGDQIFQAKGHEYSSLALLGNQADDAKRFEDGDFATIYLAPKDYHRIHMPIKGTLSKMTYVPGDLFSVNPLTAENVPGLFARNERVVALFETEIGPMAMVLVGATIVASIETVWAGTVTPPAGKKVFTWDYPTEGPDVITLDKGDEMGRFKLGSTVVMLFAKDALDEFAKDVVPKAVTRMGQPFAKIED
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1819_CLONN
Sequence: MSGHSKWHNIQAKKGKNDAAKGRIFTKIGRELILAARDGGSNPDTNAKLRDVIAKAKAANMPNDTIDRAIKKGAGELEGITYEEIVYEGYAPGGVAVMVKCLTDNRNRSAASVRHKFDKYGGNLGANGCVSYMFQRKGQLVIEKTDEIDEDELMMQALEAGAEDFSAEEEVFEITTDPEDFSAVREELEKNGYTFLEADVTMIPDVMAAVDMETAPKTQKLLDMLEEDDDVQDVYHNAEYPEEFEG
What are the official names of this protein?
Probable transcriptional regulatory protein NT01CX_1819.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTN7_RAT
Sequence: MVQACEGRSRAQLPTLSLGADMTQPPPAKAPAKKHVRLQERRGSSVALMLDVRSLGTVEPICSVNTPREVTLHFLRTAGHPLTRWTLQHQPPSPKQLEEEFLKIPSNFVNPEDLDIPGHASKDRYKTILPNPQSRVCLGRAHSQEDSDYINANYIRGYDGKEKVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLREGKEKCVHYWPTEEEAYGPFQIRIQGMKEHPEYTVRHLTIQHQQECRSVKHILFSAWPDHQTPESAGPLLRLVAEVETPETAANSGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAAQLPPETDP
What is the function of this protein?
May play a role in the regulation of T and B-lymphocyte development and signal transduction.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 7, Hematopoietic protein-tyrosine phosphatase, HEPTP, Protein-tyrosine phosphatase LC-PTP.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: ERFD_YEAST
Sequence: MCDSHQKEEDNANTSERALFFNYHEFSYSFYEDLGSEDAKPTEHDEDHKLCITHFPNVYAARGSAEFQVTRVVRVPRRFDESRSSLETPQFSTQLPGSEPAAIVGDDGTSFVRCGRYDIGDHVFGCSSVSPLSEYLSAAELAEVVHRVNGFLLREEGEVFGWRNLSGLLLDMLTGGLWSWVLGPLLSRPVFQESLALEQYVAQLNSPGGLLHERGVRLVLPRRSGCLSLDFVVPRPK
What is the function of this protein?
The ERF2-SHR5 complex is a palmitoyltransferase specific for Ras proteins (PubMed:12193598, PubMed:12379641, PubMed:7532279).  Palmitoylates RAS2, which is required for its proper plasma membrane localization (PubMed:12193598, PubMed:12379641, PubMed:7532279).
What are the official names of this protein?
Ras modification protein ERF4, Hyperactive Ras suppressor protein 5.
What is the protein family that this protein belongs to?
Belongs to the ERF4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: YODC_ECOLI
Sequence: MSFMVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGYGVKREAFHETELVPGEGSRSAEEV
What are the official names of this protein?
Uncharacterized protein YodC.
Protein: VF233_ASFM2
Sequence: MILIASPFSLAHLEYLNTWHANIKNIAQQHGLDIKVAIVVSKTHLNNFLPFSTALNIECITFPGCGIKEIDLLWARIKLFQHYCAIGARLLWLVSADIRPSVSTWPAIADSLKKGADAVVVPYPSQWNNLIPTVIKEIVVHQKKCLVAVDAHHLDTDTQIVGAGMGCIVLTLKALMVRLSIGKQPIKILWPDLHGTAEGIPLEGVEVGWFLNAYAHKLNIRCLGAEHIAQHLN
What are the official names of this protein?
Uncharacterized protein H233R, pH233R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H233R family.
Protein: PYRB_DEHM1
Sequence: MTNTPKTPAETETLLSEVQGWKHRHVLDLDNFSREELDMVMQTAGVMLDILSRPVKKVPALKGKTIATLFYEPSTRTRSSFELAAKSLSADVLNLNVSQSSVSKGESLLDTLDTLEALGADMVVMRHPLSGAPYLAANHCRANIINAGDGWHAHPSQALLDIFTILRHKPALEGLKITLIGDIKHSRVAHSNIWGLSKMGAEITLCAPYTLLPEGLNTDSQIFPEVTVKTDIKQAVSGADVVMGLRLQRERQQSGLLPGIREYAQYFQLNAEILKLAKPDALVMHPGPVNEDIELSQSVVHGEQSVINEQVKNGVAIRMALFYLCSGSKEI
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: VIRBB_BARQU
Sequence: MNQNLHKLSNETVAIVLTKLEPISAFLKDKSLFEIVINRPYQVMTEGIEGWKTIEAPALSFDELMGIAKVVASYSKQKISDKNPILSATLPGNERIQIVIPPAVEKDTISMTIRKPSSRNFSLEELANKGLFSVCEQVSFTPLNDYQSRFSELKHIEHSLATAYSNKDFVSFLNQAVKCQKNILIAGKTGSGKTTLSKALIAKIPDNERIITIEDTPELVVPQPNYVSMIYSKDGQGLASVGPKELLESALRMRPDRILLQELRDGTAFYYIRNINSGHPGSITTVHASTALAAFEQMTLLVKESEGGGDLERDDIRGLLISMIDIIVQCKRVEGKFKVTEIYYDPFKQRNIFGGN
What is the function of this protein?
Component of the type IV secretion system VirB/VirD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function.  Altogether with VirB4, may be implicated in providing the energy, via hydrolysis of ATP, for the assembly of secretion system and substrate transport.
What are the official names of this protein?
Type IV secretion system protein VirB11.
What is the protein family that this protein belongs to?
Belongs to the GSP E family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: Y059_OSHVF
Sequence: MHKLLVIIAHIIVCAYADFTGFDNEAGAVENNNDNNINLEYKPPTLRHGAGISCVIRPGDFTHVAISNDFFNRANLPAGFVNVNLEVTDFASSARCKAQLESLAPDDTLTTLITGAANCEIDQGGVTMVVYLKKNPEEIYLKNWRCGYKGSGDYVYKTLALQKTIKGQWGDSTDADSPIHPPLITLAARVETSTETEITLTCQRNNRGVTTTYFTGAPFKTVEFTGAENFRAKGDLYGRDLTPSVVPQCVINTPGDPVFKFKNLGPEDYSSKCYSGFLSTTLPEIKPKFTLLRNPYDVDFNGYEPNDVTMDFDTDSLFLFDRNVNMDRVVIDKHPYMVMKFLKPRNFHETPLLNHVDPNQPKHTFMTSISFTMLNLLLGQQLHKATAIQTVEVIKNSGDSASITCPFDSSVEEYLAIFLLDTSTCSVSLSNRNDVVQYNNSCVDPTNFYLLSSRSTSNDQTFTIDLTGNEACISKYATCIYKKKVPGITNILLLPADFASRDKIPDLSDKDVEDTDNCEEDPGLIKTLERGIRLLTFSDSYSYDYHLDQYNVLTGDGCAQLINPCEYDTTASAMKELGRVASVRVPIRFLNKFPDKKIWQCSMYDTDSDKMSWNEMRDNVACSGTELYKSLITPPKPSVYRSDENNFKISCGIIHRSCINKGINTSAVLSGTEIEDTLLEEGEEFTISQYDLLIKNKVLKCETEWGVGESFISDLLPTNSGCSVSGSCVFIDMNTIRCFYDSKNCYSHNINNVKVVFRINDADVPGANVKLSETNRFEDGFFHFLYPVASIVSIPTKNTIGFKLVDEWQRETDEFTVPYPTVEQWAFILESGIECDYTELSSAVLDVSMGRYTGETTITLQYDMYNFPECKTNENETSVDYYLQIRGEIGTSRARREDEDKSMTEWKNLVYISVHDDGDGVVTWQPISNQRDYNLDIFDNKILAAFRYRLTQEKITELFGPYINSLEVRVITESLDKGVYEATKEYLDQTMAYRTLMIPRIPPQPPITTATTQPPIDVMITTQSPNKPTEDEKSLDLEMIGKIILLIAFVIVFVILLTIGIITLVKRHRETLPEDEYLLP
What are the official names of this protein?
Uncharacterized protein ORF59.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: BOLA2_ARATH
Sequence: MVTKEQVEASLTSKLKPIHLEVIDISGGCGSSFEVEVVSEQFEGKRLLERHRMVNAALEEEMKEIHALSIKKAQTPQQWKPPSQDSATLTKDA
What is the function of this protein?
May act either alone or in interaction with glutaredoxin as a redox-regulated transcriptional regulator, or as a factor regulating Fe-S cluster biogenesis (Probable).  The GRXS17-BOLA2 heterodimer binds a labile, oxygen sensitive iron-sulfur cluster (PubMed:24714563).
What are the official names of this protein?
Protein BOLA2.
What is the protein family that this protein belongs to?
Belongs to the bolA/yrbA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MOB1_NEUCR
Sequence: MSSFLTTVNQRTRNQFRPRASGKGGATSYQLRQYAEATLGGGSLRKVVKLPEGEDENEWLAVNMVDFYNQINLLYGAITEFCSPQTCPEMKATDEFEYLWQDTENYKRPTKMPAPAYIEQLMSWVQGNIDNEAVLPSRIGVPFPKSFPALVRQIFKRMYRVYAHIYCHHYPVIRELGLEPHLNTSFKQYVLFIDEHNLATGKDFWGPLGDLVDSMLRSD
What are the official names of this protein?
Probable maintenance of ploidy protein mob1.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
Protein: HTSF1_PONAB
Sequence: MSGTNLDGNDEFDEQLRMQELYGDGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAWFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDPRKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPGKESEEGCPKRGFEGSCSQKESEEGNPLRGSEEGSPKKESKKKTLRNDCEENGFAKESEDDPNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESNEKEDEEYADEKGLEAADKKEEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSNEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDDI
What is the function of this protein?
Functions as a general transcription factor playing a role in the process of transcriptional elongation.  May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation (By similarity).
What are the official names of this protein?
HIV Tat-specific factor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HTATSF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y336_METJA
Sequence: MTTENIISGIAIADLAPYRFGKITSTGIGFGTSTVSDDSISIDADGVIINSRAIYTAGMYVDLKVNGVQKVEIKEGESIAPGDYVIPSTDGSGKAVKSPIKAGFKVASVEGNYCTIILR
What are the official names of this protein?
Uncharacterized protein MJ0336.
Protein: RL21_CHLAB
Sequence: MKSYAIIQTGSKQYQVSEGDIIDVELLDGVSEGQEIVFDQVLFTFDGSKVSLGTPTVKNAVVKGELLSRVRGEKVIAYKYKRRKNYHRKIGHRQNYLRVKISNLVM
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PEPE_CHICK
Sequence: MRSLALLCAVLALSDGITRLPLERGKKLREILREKGLLHHFLQHHRYDIGTKFPHAFPDVLTVVTEPLLNTLDMEYYGTISIGTPPQDFTVVFDTGSSNLWVPSVSCTSPACQSHQMFNPSQSSTYKSTGQNLSIHYGTGDMEGTVGCDTVTVASLMDTNQLFGLSTSEPGQFFVYVKFDGILGLGYPSLAADGITPVFDNMVNESLLEQNLFSVYLSREPMGSMVVFGGIDESYFTGSINWIPVSYQGYWQISMDSIIVNKQEIACSSGCQAIIDTGTSLVAGPASDINDIQSAVGANQNTYGEYSVNCSHILAMPDVVFVIGGIQYPVPALAYTEQNGQGTCMSSFQNSSADLWILGDVFIRVYYSIFDRANNRVGLAKAI
What are the official names of this protein?
Embryonic pepsinogen.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: Y2085_BACHK
Sequence: MKKTFYHYMMKHRAALFSNEISNLAEAMYDDLSFPKQSEDYDEISSYLELSGMLESMSIFDEAWDLYIQDR
What are the official names of this protein?
UPF0346 protein BT9727_2085.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: GHRB_ECO81
Sequence: MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_RHILW
Sequence: MERPELPIGLPEDIEEKKAAARSWFEGLRDTICASFEALEDELEGPLSDQEPGRFVAKDWSRENGAGGGGRMSMMEGRVFEKVGVHTSTVHGEFSPDFRAQIPGAKDDPRFWASGISLIAHPVNPNVPAVHMNTRMVVTSSRWFGGGADLTPVLSRRRTQEDEDSQLFHKAMEIACRNHAVADYDAYKAWCDDYFFLKHRNEARGIGGIFYDWLHSNEDAGGWDADFAFTRDVGRAFSMVYPKIVRSNFNKLWTEADRDEQLIRRGRYVEFNLLYDRGTIFGLKTGGNVESILSSLPPVVRWP
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETL_FICCA
Sequence: MFTITSYFGFLLAALTITSAIFIGLNKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TRPB_SODGM
Sequence: MTRLNPYFGEFGGMYVPQILMPALIQLEDAFVSAQSDPAFQAEFSDLLTNYAGRPTPLTLCRNLTAGTRTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALSSALLGLKCRIYMGAKDIERQSPNVFRMRLMGAEVIPVHSGSSTLKDACNEALRDWSDSYERAHYMLGTAAGPHPFPTIVREFQRMIGEETRAQLQEHEQRLPDAVIACVGGGSNAIGMFADFIDEPAVRLIGVEPGGLGIETRQHGASLKHGRTGIYFGMKSPMMQSAEGQIEESYSISAGLDFPSVGPQHAYLDSIGRAEYISATDEEALDAFRRLSRHEGIIPALESSHALAHALRMIQAEPEKEQILVVNLSGRGDKDIFTVHDILKARGDI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RBM8A_CAEEL
Sequence: MSDNEVEMEDVVANAERSRGRGLAQSRNRERITYDVVDEESSATSGAPQRSVEGWIVFVTNIHEEATEDDVHDKFSEYGKIKNIHLNLDRRTGFLKGYALVEYETQKEANEAIDQSNDTDLLGQNVKVDWCFVKGKKTSGKR
What is the function of this protein?
RNA-binding protein which binds to pre-mRNA, spliced mRNA and spliceosomal snRNAs (PubMed:14706697, PubMed:23149939).  Preferentially binds to the spliceosomal snRNP U2 (PubMed:23149939).  Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs (By similarity).  Positively regulates the nuclear export of spliced mRNAs including the sex determination gene tra-2 (PubMed:23149939).  Promotes oogenesis by repressing germline masculinization and spermatogenesis (PubMed:14706697).  Required for embryonic development, possibly through positively regulating the expression of pie-1 (PubMed:14706697, PubMed:30279189).  Not required for the spatial patterning of pie-1 in embryos (PubMed:30279189).
What are the official names of this protein?
RNA-binding protein rnp-4, RNA-binding protein 8A, RNA-binding protein Y14, Ribonucleoprotein rnp-4.
What is the protein family that this protein belongs to?
Belongs to the RBM8A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle.
Protein: RUTB_METED
Sequence: MEADAPAGYRDPSGRHGAVTLPARPEPIAFDADATVLIVVDMQNAYATKGGYLDLAGFDVSATGPVIERIARAVAAARAAGIRVVWFQNGWDPDYVEAGGPGSPNWHKSNALKTMRRRPEMNQRLLAKGTWDYALVDALTPEPGDIVLPKPRYSGFYNTPLDSMLRARGIRTLVFTGIATNVCVESTLRDGYHREYFGIVLADATHQAGPPALQEGALRNIETFFGWVSDVAAFEAALSSDEARRIPA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: STKL1_MOUSE
Sequence: MLNPGALGVNLVVEELETETKFLIKQVECIDEHHANKALEELMPLLKLQHPNLSLYHEMFIMWNNEISSLFLCLVMDYYSQGTFQNIMENKRKLKAVVDTEWMHTMLSQVLDAIEYLHKLNIVHRNLKPSNIVLVNSGYCKLQDMSSQALMTHEAKWNVRAEEDPCQKSWMAPEALKFSFSTKSDIWSLGCIILDMATCSFLNDTEAMQLRKAIRHHPGSLKPILKTMEEKQIPGTDVYYLLLPFMLHINPSDRLAIKDVMQVTFMSNSFKSSSVALNMQRQKVPIFITDVLLEGNMANILDVMQNFSSRPEVQLRAINKLLTMPEDQLGLPWPTELLEEVISIIKQHGRILDILLSTCSLLLRVLGQALAKDPEAEIPRSSLIISFLMDTLRSHPNSERLVNVVYNVLAIISSQGQISEELEEEGLFQLAQENLEHFQEDRDICLSILSLLWSLLVDVVTVDKEPLEQLSGMVTWVLATHPEDVEIAEAGCAVLWLLSLLGCIKESQFEQVVVLLLRSIQLCPGRVLLVNNAFRGLASLAKVSELVAFRIVVLEEGSSGLHLIQDIYKLYKDDPEVVENLCMLLAHLTSYKEILPEMESGGIKDLVQVIRGRFTSSLELISYADEILQVLEANAQPGLQEDQLEPPAGQEAPLQGEPLFRP
What are the official names of this protein?
Serine/threonine kinase-like domain-containing protein STKLD1, Serine/threonine kinase-like domain-containing protein 1, Sugen kinase 071.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
Protein: VHED_BPFSA
Sequence: MFKRKSTAELAAQMAKLNGNKGFSSEDKGEWKLKLDNAGNGQAVIRFL
What is the function of this protein?
Binds preferentially to single-stranded DNA and therefore, destabilizes double-stranded DNA.  It is involved in DNA replication, repair and recombination.  Binds ss-DNA as the replication fork advances and stimulates the replisome processivity and accuracy.
What are the official names of this protein?
Single-stranded DNA-binding protein, Gp32, Helix-destabilizing protein.
Protein: UD15_RAT
Sequence: MGLHVTLQGLAGLLLLLYALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTLQTYPVPYTRQGFRQQMMRNIKVVFETGNYVKTFLETSEILKNISTVLLRSCMNLLHNGSLLQHLNSSSFDMVLTDPVIPCGQVLAKYLGIPTVFFLRYIPCGIDSEATQCPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLALKYICHFSFTRYESLASELLQREVSLVEVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINCVIKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH
What is the function of this protein?
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile.  Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds.  Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist zolarsatan, a drug which can inhibit the effect of angiotensin II.
What are the official names of this protein?
UDP-glucuronosyltransferase 1A5, UGT1A5, B5, UDP-glucuronosyltransferase 1-5, UDPGT 1-5, UGT1*5, UGT1-05, UGT1.5.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: GLYA_ACIAD
Sequence: MFANISLSEFDPELAKSIEAEDARQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYGGCEYVDVIEQLAIDRAKALFGADYANVQPHAGSQANSAVYLALLNAGDTVLGMSLAHGGHLTHGAKVNFSGKTYNAVQYGLNPETGEIDYDEVERLAIEHKPRMIVAGFSAYSRIVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPSPVQIADVTTTTTHKTLRGPRSGLILAKANEEIEKKLQSAVFPGNQGGPLVHAIAAKAVCFKEAMAPEYKAYQQQVVKNAQAMAEVLIARGYDIVSGGTDNHLFLLSLIKQDVTGKEADAWLGNANITVNKNAVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRDLASWIADVLDSKGDEKVIADVKAKVEAVCAKFPVYEN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIGD2_MOUSE
Sequence: MLGKRKRVVLTIKDKLDIIKKLEEGNSFKKLSVLYGIGESTVRDIKKNKERIINYANSSDPTSGVSKRKSMKSSTYEELDRVMIEWFNQQKTDGIPVSGTICAKQARFFFDALGMEGDFNASSGWLTRFKQRHGIPKAAGKGTKLKGDETAASEFCGNFQEFVERENLLPEQIYGADQTGLFWKCLPTRTLAFDTDQSTCEYRTSRERIIIMCCANATGSHKLNLCVVGKAKRPRAFKGTDLSNLPVTYFSQKSAWIEPSVLKQWFEKCFVPQVQKHLKSKGLREKAVLLLDFPAAHPAEELLSSDDGRIIVKYLPPNVTSLIQPMSQGVLTTVKRYYRAGLIQKYMDEGNDPKTFWKNLTVLDAIYEASRAWNQIRSNTITRAWKKLFPGNEENPSVSIDEGAILAANLATVLQNTEDCEHVNIENIEQWFDSRSSGSNCQVLADIVGAADRAKVTEQKPSRKTRKAELNPEKHISHKAALEWTENLLDYLEQQDDMLLSDKLVLRRLRTIIRRKQRIQNKSHL
What are the official names of this protein?
Tigger transposable element-derived protein 2.
What is the protein family that this protein belongs to?
Belongs to the tigger transposable element derived protein family.
What are the subcellular locations of this protein?
Nucleus.