PharMolix/UniProtQA huggingface dataset:
Protein: SIX1A_DANRE
Sequence: MSILPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESYQFSTHNHPKMQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRSVLREWYTHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENGENNGVGGKQSQRSPLDGVKSLMSSSEDEFSPPQSPEHSSVLLLQGTMNNPAAPAYPMPGLGAPHPLHGMQGHPHQIQDSLLGSLTSSLVDLGS
What is the function of this protein?
Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development.  Depending on context, functions as transcriptional repressor or activator.  Plays an important role in the development of the inner ear, where it promotes hair cell proliferation and inhibits proliferation of neural progenitor cells (By similarity).  Required for normal myogenesis.  Plays a role in the development of fast muscle fibers throughout the body, as well as the development of craniofacial muscles.
What are the official names of this protein?
Homeobox protein six1a, Homeobox protein six1b, Sine oculis homeobox homolog 1a, Sine oculis homeobox homolog 1b.
What is the protein family that this protein belongs to?
Belongs to the SIX/Sine oculis homeobox family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MINC_PELTS
Sequence: MSREMISIKGTRNGLVFFLDPTREFEEIKNTLLSKMESARGFFKGAKFSISHGQKDMPVEQKNELVNICRRYGLIPNNDDAAVPANAVSKASPRATRAASNSKPTIGENALMVRRSLRSGQCISYPGHVVVIGDVHPGAEVISGGNVLVMGSCRGLIHAGAGGNLMAKVVALRLAPTVLSIAGQRYAPEHPSAIPPGCQVARLSGQEIIFEKFQAAR
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: RS6_ECOSE
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MATK_ACOGR
Sequence: MEEFKVYFEKDGSRQQYFLYPLLFQEYIYALAHNHVLNGLIFYESSENFVYDNKFSLIIVKRLITQMYQQNSLSNLVNDSNRNRLVRQNKNFYYQTILEGFSVIMEIPFSIIFLSSVEEKKEKIPKIQNLRSIHATFPFLEDKLSHLNHVSDILIPYPIHLEILVQVLQGWIQDVPSLHLLRFFLHEFHNWNSLIIPKKSISFLFSKGNQRLFLFLYNSYVFECESALVFLRKQSFYLRSTSXGXFVERTHFYGKXEHIVVVRRKNFQKALSLFKDPFIHYIRYKGKSILASKGTHFLMKKWKYHLLNFWQCRFYFWSQPHRIHINQLSNRSFYFMGYLSSVRINFSTVRSQMLESSFLMDTPTKKFDTIVPIIPLIGSLVKAKFCNVSGHPVSKPVWADLSDADIIDRFGRICRNLSHYHSGSSKKQSLYRVKYILRLSCARTLARKHKSTVRAFFKRLGSEFLEEFFTDKEQVLSLIFPSLRSPSHRVHKGERIWYLDIIRINDLVNNS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIAA_LEUCK
Sequence: MTKIVVIAGPTASGKSDLAISVAQRFNGEIVSADAMQIYRGLDIGTAKVTKAERELVPHHLIDIVDMTDKFSVAEFVTRADQVINDIAKRGKLPVIAGGTGFYVKALLGQQPLDFVASDEAEVALLKQKSLPTLVTMLKAADTILASRVDLNNKQRVIRAIQIARHGKRQEDISRPTYDALIVGIDWPREILYERINRRAQKMLDDGLLSEVEHIMSVGGESIQAGKAIGYKEFFPYIRGEVTREQALLAVQQDSRRYAKRQLTYLRHQIPGLIWLHGTDAATKLTSEVKAWLD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: YR641_MIMIV
Sequence: MPFNSDNMTELINKFKLESTIYKNKRWIEIGCFMDKIVIEIHKDKYKNLIDFNTEDVKIIGKNAYMTEMRAYEYVKKLYSHPEHHNIHQVLGLVGRFKKKQEIMTLAIIYDYFRDRYNMQYQCPELDFKIDTNLVIESGLTGGLAIEVDECGHSTYKQADHEDRQKILEACGYYFVRIKPADFTNEELIEFVKQKIDEYQLIYSKEIDPETLWKALKDNSIDRQFFDVIGKSIVSAKKFCGLLSKRRCCKKIAIQLSRKCGLR
What are the official names of this protein?
Uncharacterized protein R641.
Protein: KAD_GEOSL
Sequence: MNLVFLGPPGAGKGTQANLLTRTYEVPQISTGEILRAAVKSKTPMGVKAKEYMDQGALVPDSVVVGIVEERLASPDCASGFILDGFPRTVAQADALKQVLGALGKQIEHVVSFEVDKGVLLERIVGRRVCRACGRAFHVKFDPPLVDGVCDACGGELYQRDDDREDTMRRRLEVYDEQTAPLKSYYEGERLLRKVNALEPIEDVQRQIVKLVESCNG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_STAA2
Sequence: MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_BRUSU
Sequence: MIPITALKDKTVALFGLGGSGIATAKAIVAGGARIIAWDDNPDSVARAQSAGIATGDLRQADWSQFAVFVLSPGVPLTHPQPHWSVDLARAAGVEIIGDVELFVRERNHIAPDCPFIAITGTNGKSTTTALIAHIIKATGRDMQLGGNIGTAILTLEPPCADRFYVVECSSYQIDLAPSLNPTAGILLNLTPDHLDRHGSMENYAAIKERLVAASGTAIIGIDDAYCQAIADRLHGAGIRVVRISKEKHLDRGYFADGAKLLWAQDGEIDEIASLEGIGSLRGAHNAQNALAAIVACLSAGLSLEEIHAGLKSFPGLAHRMEQVGRRGKVLFVNDSKATNAEATAPALSSFPQNIYWIVGGVPKAGGINSLTAFFPRVAKAYLIGEAAAQFAATLGGAVPFEISDTLAAAVAHAAGDAGNDAAPEPVVLLSPACASFDQFQNFEKRGDAFRDAVLALPGVMPMRGES
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_SHIFL
Sequence: MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_CHLPD
Sequence: MSLTQEDKAGIISQFGGVQQNTGKAEVQVALFSRRITDLTGHLQQHPKDKHSRRGLLMLVGKRKKVLNYLKNVDIERYRTVIAELDLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PSBH_ADICA
Sequence: MATKVLDETPKGKPKISFLGMVLKPLNSEYGKVAPGWGTTPLMGFFMALFAIFLVTILEIYNSSVLLDGIAISW
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PANB_BACC0
Sequence: MKTKTDFLKMKEQGEPITMLTAYDYPSAKLAEEAEVDMILVGDSLGMVVLGYDSTVPVTVEDMIHHTKAVRRGAKETFIVTDMPFMSYHVSLQDTMVNARRIVQESGAHALKVEGAGEVISTIHYLTNAGIPVVAHLGLTPQSVGVLGGYKVQGKDAESAKKLIEDAKKCEEAGAIALVLECVPMQLAELISEQLTIPTIGIGAGQKVDGQVLVYHDLISYGVNRVPKFVKQYTSVQEEIVRGISQYVAEVKTRQFPEEKHSFTMKEEECLALYGGKQS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPA_SALDC
Sequence: MPFTLGQRWISDTESELGLGTVVAMDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHEGWQLHIDEVKEENGLLVYVGTRLDTEETNVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPYSGLRGQRTNLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYTEAQHDAYNPFETEQLVICSLDFARRNKQRLEHLCDAEWDLLVVDEAHHLVWSTDAPSREYMAIEQLAERVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQKNYRPVADAVAMLLAGNKLSNDELNRLGDLIGEQDIEPLLQAANSDRDDAQAARDELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTVKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKATTALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRAIYDSAYASLINYLAAPEETDGFDDLIKSCREQHEALKAQLEQGRDRLLEIHSNGGEKAQQLAQSIEEQDDDTNLIAFAMNLFDIVGINQDDRGDNLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELVYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLSAVNRHTGSKLVNAVQQDVHAILQLGETQIEKSARALIDNARREADEKLSGELSRLEALRAVNPNIRDDELAAIDSNRQQVLESLNQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: RR11_CYAPA
Sequence: MARQIKRSGTTKQKKNIPVGVAHIQSTFNNTIISITSPTGEVIAWASAGSSGFKGARKGTPFAAQTAAENSARQAMEQGMRQIEVIISGPGSGREMAIKALQATGLEISLIRDITPVPHNGCRPPKRRRV
What are the official names of this protein?
Cyanelle 30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: RS12_CHLMU
Sequence: MPTINQLIRKKRQSGATRKKSPALQKSPQKRGVCLQVKTKTPKKPNSALRKVAWVRLSNGQEVIAYIGGEGHNLQEHSIVLVQGGRVKDLPGVRYHIVRGALDCAAVKNRKQSRSRYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: PYRB_CHLTE
Sequence: MNHLTGLFGLPASTLVELLDLATGYREGLNREPETFAPLLSNRRIALVFFENSTRTRFSFELAARHLGAGTLSFTAASSSVSKGETLSDTIRNLEAMKVDAFVLRHPSSGAAEFVASITKRPVINAGDGTHEHPTQALLDLLTLREYFGKIEGLKIMILGDILHSRVARSNIIGLKTLGAEIAVCAPTTLLPGRIDQLGVRVFTGIDEALAWADAAIVLRLQLERATGGYIPSLEEYSASYGLTDEKLDRLKRLMPVLHPGPINREIEISNLVADRIQPPGYSSSMLMEQVTNGVAVRMAVLHRLLAK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: YTM1_VANPO
Sequence: MSSDSSQVKLRFFTREQDESLHVQDAPMYAPISLKRYGLSEVVNHLLGFEKPVPFDFLIDGELLRISLQEYLTKHGLSSETFLNVEYTRAVLPPSFLSSFSNEDWVSSLDVGDNNKIISGSYDGVVRTWNLSGKIEKQYSGHSAPIRAVKYISNTRMVSGGNDRTLRLWKTKNEDLKQPVVDEDDEDIEDGKTLAILEGHKAPVVSIDVSDNSRILSGSYDNTIGFWSTIYKEMTVVDPMEELKNNDSKMSTAAKKRRKLTLKDGTIRRRAPLALLESHTGPVEQVSFDFKDNTVGYSISQDHTIKTWDLVTSRCIDTKTTSYSLLSLAQLPTLNLLACGSSARHITLHDPRIGSTSKITQQQLVGHKNFVVSLDTCPENEYMLCSGSHDGTVKVWDVRANSPMYTITREEQSVEKGVNDKVFAVNWSKNVGIISAGQDKKIQINKGDNIFKS
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein YTM1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: DEFL_STAAC
Sequence: MAIKKLVPASHPILTKKAQAVKTFDDSLKRLLQDLEDTMYAQEAAGLCAPQINQSLQVAIIDMEMEGLLQLVNPKIISQSNETITDLEGSITLPDVYGEVTRSKMIVVESYDVNGNKVELTAHEDVARMILHIIDQMNGIPFTERADRILTDKEVEAYFIND
What are the official names of this protein?
Peptide deformylase-like, Polypeptide deformylase-like.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RL22_STRP4
Sequence: MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTPNKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTAHITVAVAEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: UPP_SHESA
Sequence: MKVVEVKHPLVRHKIGLMREGDISTKRFRELAAEVGSLLTYEATADFETETVTIEGWNGPVEVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFEKLASDMNERIALIVDPMLATGGSMIATIDLLKKRGCTSIKALVLVAAPEGIKALEAAHPDVELYTAAIDRCLNEKGYILPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SECA_PECCP
Sequence: MVMNILTKIFGSRNDRTLRRMRKNVDVINRLEPEMEKLSDEELQAKTLEFRVRLEKGESLENLLPEAFAVVRESSKRVFGMRHFDVQLIGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGRGVHVVTVNDYLAQRDAENNRPLFEFLGLSVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLYYALVDEVDSILIDEARTPLIISGPAEDSSELYISVNKIIPHLIRQEKEDSDTFHGEGHFSVDEKARQVNLTERGLVLVEELLVKEGIMEEGESLYSPTNIMLMHHVTAALRAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEKVTIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTIVVPTNRPMIRKDLPDLVYMTEQEKIDAIIEDIKERSVKGQPILVGTISIEKSEVVSHALEKAGIKHNVLNAKFHAMEADIVAQAGQAGAVTIATNMAGRGTDIVLGGSWQAEVALLENPNDEQIAEIKAAWKVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSNMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYTQRNELLDVSDISETITSIREDVFKATIDSYIPPQSLEEMWDVEGLEQRLKNDFDLDMPVKAWLDKEPELHEETLRERIFQQALEVYHRKEEVVGSEVMRNFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEIEALEQQRREEAERLARQQQLSHQEEDSLNTGSPAQADRKIGRNDPCPCGSGKKYKQCHGRLQK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: YBEY_LEGPH
Sequence: MTYHIDIQNATGKLLPLSEDEITKLASLALRDHKQDAELTVRLVDVEEMTYLNHTYRKKNKPTNVLAFPCSLPANIELECPLLGDVVICPEVLLAESAQFNKSLHAHWSLILIHGVLHLLGYDHIKDEEASIMQMLEAKLLAELGYANPYEVEENELE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_XANOM
Sequence: MARTRNRFDRTPFQTAITDLSHDGRGVARRDGEGGKVTFISGALPGELVRAEPTARSRHFDEAKTVEVLEASPQRVAPRCPHFGVCAGCVLQHLEESQQIVAKQRVLMDNLERIGHVTPQAVLPGLTGDNWGYRRKGRFSVRRVEKKAKTLVGFRELDPRFVADLSVCYTVIPQIGEKIPLLAALVEGMDGKRDIPQIEFIAGDDAVALTIRHMQPLSARDQQAWIAFAQEHGFAIFLQPGGVDSVHPLWPQEVPLSFRLPQWDVDLAFRPLDFIQVNASLNQKMIVHALALLDAKPDDRVLDLFCGLGNFTLPLARVVREVVGVEGDAGLVARAKDNAQRNGLDNAQFYAADLTQDQRNAAWMRQGFDKLLLDPPRSGALEVLQQLPLKTFERIVYVSCHPGSLARDAGYLVNEQGFTLVSAGAMDMFPHTAHVESIAVFERR
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: RL40_RAT
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKVK
What is the function of this protein?
Component of the 60S subunit of the ribosome.  Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
What are the official names of this protein?
Ubiquitin-60S ribosomal protein L40, Ubiquitin A-52 residue ribosomal protein fusion product 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [60S ribosomal protein L40]: Cytoplasm.
Protein: PECR_PONAB
Sequence: MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAGELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDIFGKINFLVNNGGGQFLSLAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVSIKTGLPLAVHSGAARAGVYNLTKSLALEWACSGVRINCVAPGVIYSQTAVENYGSYGQSFFEESFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEIPDHDNWPKGAGDLSVVKRMKETFKEKAKL
What is the function of this protein?
Participates in chain elongation of fatty acids.  Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA.  Has no 2,4-dienoyl-CoA reductase activity.
What are the official names of this protein?
Peroxisomal trans-2-enoyl-CoA reductase, TERP.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: IHFA_ERYLH
Sequence: MSRSVGTLTRADLAEAINRKMGFSRAESLDMVEAILEHMCGALRKGENVKISGFGSFVLRDKKERIGRNPKTGVEVPITPRRVMTFRASQLLRERIAKGG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ESR2_PIG
Sequence: MDIKNSPSNLNSPVSYNCSQSVLPLEPGPIYIPSSYVESCHEYSAMTFYSPAVVNYSISSNSEVGPGRQATSPNVLWPTPGHLSPLAIHCQPSLLYAEPQKSPWCDTRSLEHTLPVNRETLKRKASGSSCASPVTSPSSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRKQRNSEGHLHCLSRAKKNGDHTTRVKELLLSTLSPEQLVLTLLEAEPPHVLVSRPSTPFTEASMMMSLTKLADKELVHMISWAKKIPGFMELSLYDQVRLLESCWLEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPSAAAQEAESSRKLTHLLNAVTDALVWVIARSGISSQQQSVRLANLLMLLSHVRHASNKGTEHLLNMKCKNVVPVYDLLLEMLNAHTLRGNKSLVTGSERSRMEESESKEGSQKPQAQ
What is the function of this protein?
Nuclear hormone receptor.  Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
What are the official names of this protein?
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RMUC_ECO57
Sequence: MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAELSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIRQMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSFGKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASGLREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTRESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPAFLLALDRQPELITEALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFIDDMSAIGQSLDKAQDNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEYRLRSVPEQPNDEAYQRDDEYNQQSR
What is the function of this protein?
Involved in DNA recombination.
What are the official names of this protein?
DNA recombination protein RmuC.
What is the protein family that this protein belongs to?
Belongs to the RmuC family.
Protein: SET5_KLULA
Sequence: MVHLKLETLRLNDEDQSTGSSLITPSRTQLCDEVVRWWKEEPAAEDMLIDTLYEHLIRRRSNWSVTKDELYQALKSHKLYTPELNELDSYTGDIRPSTVTDADIAQLNKKLLDKVTIADTEFGKGLVATDDIRKGGLVFHEQLPLTVIPQLDKQPLVSRGKCCGLCSAFTTLSSQLIIKNNLDCNMCNTIWCSKQCKKLDTTHSVLKHATSRNSLCNSSNWIKFENFCLQESLVAAYAVGVIYARHVMQPTSNLWKLFTSLCSVSQRVRWQASDSINVGGTFDASCNGKLYADVSAPNMETQWSDAFEMFAKSFPKCDMDYEDFLNLTGTFNLNQIMGQVYPLVAHINHSCEPNVRYELEPKHGIKLYARKDIKKGEQLRLTYVNPLHGVTLRRRELRVNYGFLCHCPRCCQEWEKRQKIVSDPSNHAISSEAAHSSTTARRKSSMKSCRPSLKELLENGDEFDLEIPSDVNSKRRMSVRFNSHVTLAVEEE
What is the function of this protein?
Putative protein lysine methyltransferase.
What are the official names of this protein?
Potential protein lysine methyltransferase SET5, SET domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.