PharMolix/UniProtQA huggingface dataset:
Protein: PDXA2_CUTAK
Sequence: MPKTPLLGITEGDPAGIGPEITVQAIHNMADDRSFIPIVYGDPAIISRACSVTGLSETVRRVTSEEHIEPESNVINVVDTGTVPHADSIEWGSVQELAGRAAIASIEAATDAALSGKTDGVVTSPINKEAIWKTGSEFLGHTEMLGSLCGTPDTDTMFVVSGLKIFFATRHMSLREAVDSIRRDLIDHEIHKALRALKVFGCNSPKLAVAALNPHAGEGGHFGTEEIEVLRPAVKSACAEGHNVVGPVPADSVFHKGVIREYDGVLSLYHDQGHIASKTLDFDGTVSVTAGLPILRTSVDHGTAFDIAGQGAASPMTMQSALHVASDFARFVPVIREEYLPSTGRN
What is the function of this protein?
Catalyzes the NAD-dependent oxidation and subsequent decarboxylation of D-threonate 4-phosphate to produce dihydroxyacetone phosphate (DHAP).
What are the official names of this protein?
Putative D-threonate 4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family. PdxA2 subfamily.
Protein: TX1AA_ECTTU
Sequence: GVIPKKIWETVCPTVEPWAKKCSGDIATYIKRECGKL
What is the function of this protein?
Algogenic for animals, human and insects (PubMed:7826413).  At high concentrations (0. 5-1 uM), it acts as a pore-forming protein that forms nonselective cation channels both in cell and artificial membranes (PubMed:7826413).  It is weakly selective for cation over anions channel conductance is identical in both directions.  At lower concentrations (1-10 nM), this heterodimer inhibits cardiac L-type calcium currents in isolated rat cardiac ventricular myocytes (PubMed:10336635).
What are the official names of this protein?
Omega/M-ectatotoxin-Et1a subunit A, Omega/M-ECTX-Et1a subunit A, Ectatomin subunit A, EA, Ectatomin-Et1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the ectatomin family. Ectatomin-Et subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: PCDB3_HUMAN
Sequence: MEAGGERFLRQRQVLLLFVFLGGSLAGSESRRYSVAEEKEKGFLIANLAKDLGLRVEELAARGAQVVSKGNKQHFQLSHQTGDLLLNEKLDREELCGPTEPCILHFQILLQNPLQFVTNELRIIDVNDHSPVFFENEMHLKILESTLPGTVIPLGNAEDLDVGRNSLQNYTITPNSHFHVLTRSRRDGRKYPELVLDKALDPEEQPELSLTLTALDGGSPPRSGTAQINIQVLDINDNAPEFAQPLYEVAVLENTPVNSVIVTVSASDLDTGSFGTISYAFFHASEEIRKTFQLNPITGDMQLVKYLNFEAINSYEVDIEAKDGGGLSGKSTVIVQVVDVNDNPPELTLSSVNSPIPENSGETVLAVFSVSDLDSGDNGRVMCSIENNLPFFLKPSVENFYTLVSEGALDRETRSEYNITITITDLGTPRLKTKYNITVLVSDVNDNAPAFTQISYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLSSLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADLLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGQMVDVSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNFVAQGAERVSEANPSFRKSFEFS
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-3, PCDH-beta-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS19_THEAC
Sequence: MVVNKQGSVKSIKRKARKSKKVVSGRAKEFTYKGYSLEDLQKMSMEELIKILPARARRTLLREPNYEQKKLMEKLESDEEDVKTHVRDVIILPNYVGKIVEVYNGNSYFKFEIKPEMIGHYLGEFVMTRKEVKHSGPGVGATRSSKFMPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GGR_THEKO
Sequence: MTWKYDVVVVGSGIAGPIVARNVAKAGFSVLLIDKKWAIGTPKQCAEAISIKVFDKYDIPYDKRFINREIYGAKLYSPSGYELEMRYKEVSGVILERKVFDKMLAYYAAKAGADVLARTEALDVIRKDGKIVGIKAKHEDEPVEIYADIIVAADGVESTIARKAGINTYAPPHEFDSGYEYEMLIEGFDPDLIHLWFGNEVAPRGYVWVFPKDEDRANVGIGINSDNPKTAKYYLDKWLEENNIPAKKLLEINVGLIPVGGFVKELAKDNVVVVGDAARQVNPMHGGGMAEAMEAGTIASKWIVKALEEENLSLLQNYTKEWWETDGKRLEKVLKVRRVTEKLTDEDLDLFIQILSGADAEKIASGDYAEVIKALLKHPKVLMSKRRLSLLKELL
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: CH10_STROR
Sequence: MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQGVRTLNGDLVAPSVKPGDRVLVEAHAGIDVKDGDEKYIIVGEANILAIIEE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD31_ORYSJ
Sequence: MAPSFDFAASILLCAEDNTAILDLGEESEEISWVVGVDASLGDLSMDFPLQSDDCIEALLGREEQQHIPMEGYLQRLLLQPDGLDLVAVRSDAIDWIWKVHELYKFGPLTAVLSVNYLDRFLSVFDLPQEEACMTQLLAVASLSLAAKMEETVVPHPLDLQVCDAKYVFETRTIKRMELAVLNALKWRMQAVTACSFIDYYLHKFNDDDTPSTSALSRSVDLILSTCKVAEFLVFRPSEIAASVALVALEEHETSMFERVATCYKNLKKERVLRCYEMIQDKIIMRNIMRQSAGSVFSIPKSPIGVLDAAACISQQSEDTFVGSPATNYESSASSKRRRICR
What are the official names of this protein?
Cyclin-D3-1, G1/S-specific cyclin-D3-1, CycD3;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
Protein: ATG11_CANAL
Sequence: MSEISYLSINNAHNGIIIKIPKPVRFHTLSEFKKYIQQSYSIDSVDNLFLLTTFGIKLNYNLINEIGEVFVYDKRLFTNIVDQSLIDQYTQSTFRVSEPTHSPLLKSNVGFLKQNLSSNLKINQGWARIITQDGELMDQYCRELIQQINVIFKCLNTIFQFATNFTNEIEKNFSNFFNYVKLINYKTLHKSWITNYKNLKTFPTFKIDNENIKLSDFLEVDRLQSSADYIEKFLPLIVNKLNELKQVIETVNEEKLTVDKFIETSRNESISNFKNVNISNVLSQLQTESQQLTDDIENLHYKNMDEIYRLHRDKLSISIYNNAKDIYKNLNDLQQFKNKLTKASLKAFNTIANLQMKMVGVKTEMKKITTEDETATEDSKVGDVNYKTISNVKKYEDYLSLTIDLPLIFGFSLIEKRRQFEWYDFYSKGIVNNVSEQLSTIIEHEKVFRGIWLKKFGTLLSLINDDPLTPSLPNIDVTLVGNRQNNFSILYDLKIERDDIINYISLIEATNMSKNFVTLLNKNFKDLIASTNNMKKVTKVISSLSTYTTNSADDKSKSSHEEGTEEEIDFDLNLIKGLKSRIKKLENLLHQQQFKNLNNWPVIRNVPSMTNDNRQSTIIQPTVVSPARTNPTQLLSRNPSTTKENTTTNIHNNHQQSEVLDSSVIDKHLDNIRLKKLNNELQTKNTELTNQINSKNETITQQQKEMEHMKLKTEKRVDELMKKLQEKDEECQSLKQENKIKCDEVENLTKKLELSDNHNKELEAKITEYTQKATSKTKEIADLNKTVSNLRSELGDAMHMKNDLLSNLSSKEAEFTKERNQFNNDLKALQLKLDEINEDYENLMELTQAKQKKHDLIINDLNNVIINLMNDIKKTLLSVFEYFLEYCLVLESMGLLLVKEDEIYKIKRVKGLKSKKSIGDGDMSIISNGTPSSKVIEEIENEINIVNNIPPISSILPDSYSSGTESDSVVDRYNDQSMKLISTFNQLFKFNNENENENRIDHILNTLAFKNNVQLQEDSINDTRFFLNAISKRFRDVEGFAKRQAKDNKLKEQEHRKLVHRLNSKISVNGFQEKDLVLFLPTRIDRPNGENIPSNDKIQPWAAFNIGAPHYFLKTEQTKNKEWIIGRVKKITEYKVTEENVQSLESNPFQLSVNVTWYLVEADEE
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy.  Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation.  Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation.  Required for the Cvt vesicles completion (By similarity).
What are the official names of this protein?
Autophagy-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the ATG11 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.
Protein: ASMT1_ORYSJ
Sequence: MAQNVQENEQVMSTEDLLQAQIELYHHCLAFIKSMALRAATDLRIPDAIHCNGGAATLTDLAAHVGLHPTKLSHLRRLMRVLTLSGIFTVHDGDGEATYTLTRVSRLLLSDGVERTHGLSQMVRVFVNPVAVASQFSLHEWFTVEKAAAVSLFEVAHGCTRWEMIANDSKDGSMFNAGMVEDSSVAMDIILRKSSNVFRGINSLVDVGGGYGAVAAAVVRAFPDIKCTVLDLPHIVAKAPSNNNIQFVGGDLFEFIPAADVVLLKCILHCWQHDDCVKIMRRCKEAISARDAGGKVILIEVVVGIGSNETVPKEMQLLFDVFMMYTDGIEREEHEWKKIFLEAGFSDYKIIPVLGVRSIIEVYP
What is the function of this protein?
Methyltransferase which catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine).
What are the official names of this protein?
Acetylserotonin O-methyltransferase 1, OsASMT1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_THET8
Sequence: MKTAYDVILAPVLSEKAYAGFAEGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTLHVRGKKKRLGRYLGKRPDRKKAIVQVAPGQKIEALEGLI
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ENLYS_BPN15
Sequence: MANRAKLSAAVLSLILAGASAPQILDQFLDEKEGNSLTAYKDGSGIWTICRGATMVDGKPVMQGMKLTQAKCNQVNAIERNKALAWVDRNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRLNAGDRHGACEAIRWWIKDGGRDCRLTKGQKNGCYGQVERRDQESALTCWEIDQ
What is the function of this protein?
Signal-arrest-release (SAR) endolysin with lysozyme activity that degrades host peptidoglycans and participates with the pinholin and spanin proteins in the sequential events which lead to programmed host cell lysis releasing the mature viral particles.  Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm where it breaks down the peptidoglycan layer.
What are the official names of this protein?
SAR-endolysin, Endolysin, Gene product 54, gp54, Lysis protein, Lysozyme, Muramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 24 family.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein; Periplasmic side. Note=Secreted as a signal-anchored, membrane-tethered, inactive endolysin which is subsequently refolded, activated and released by membrane depolarization driven by the pinholin.
Protein: CLCB_ECOLI
Sequence: MFHRLLIATVVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDALLYNVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGGLIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAQHS
What is the function of this protein?
Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
Voltage-gated ClC-type chloride channel ClcB.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HTPX_ACTP7
Sequence: MAKRIVLFLLTNLAITFVLGIVLNIIFQVTGIQGGSTGGILVMSLVFGFAGSLISLFMSKSMALRSVGAEVIQQPRNHAEQWLFDTVQRQSQQANIPMPDIAIYHSADVNAFATGATKNNSLVAVSTGLLDNMTEDEAEAVVAHEIAHIANGDMVTMTLLQGVLNTFVIFLSRIISTAASSGKDENGNATQNTLVFWIVDIALQMIFGVIATMIAMWFSRYREYRADAGSAQLVGKEKMIAALQRLQHVHEPQEMQGSLAAFMINGARSKELFMSHPPLEKRIEALRNL
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL30_CERS5
Sequence: MAKTIIVKQVRSAARRPAVQTAVLKGLGLNKMHRTRELEDTPSIRGMVAKIPHLVEIIEERG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RL14_SHELP
Sequence: MIQMQSTLEVACNSGARRVQCIKVLGGSHRRYAGIGDVIKVSVKEAIPRGKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNANLAPIGTRIFGPVTRELRTEQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RTC5_LACTC
Sequence: MGQNSSNTVSSSQSSTHFESENDLLSWYDKKALKLVSTPELVSYKGNIDGKPLDAALNRKELMRVLRLQNANEAVEGLLFNCVQTLANFPLIKDCYENVTYMGVLKSCVLLNKNRCLEYVQDKRYNHTKLVYISLALNKAVKEMSSLPNSNDSLDAPKVIATFNNVAEEELVVPAETMLEFLTLMLTMSKATVIKNSRLDVNISEKWDSFKTCALSILRTMNTDILTSQDALKNVISYTQFQNVISSVCPNLLVPLECLMEHVLFLNRDLVDLEASKPLIPQSKLVTEPLLAQLATVWPRELVFSRLQKLYVGRDSGFSMRSFQAKAFKWMAPSILLVQGSRIPDDQDYAKNKNQRYKKFLDEYPRLKDEDQHILPALSGKRKLLFAILINEPWKVTNSELFGDIKTTIVQLSPIQEVYKASKPGNVYFNTLGGGIGIGSPQPIIKSSGVKFVPGNVSLTIDPNLEFAAFRNVGFGGSIAPSNTPTSEHKFLIQDIETWGCGGEKELEEQMKNWEWEEAEAQRRQRINLKSVNDDRALLELAGLVGQNQSGGSV
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUHB_MYCTO
Sequence: MTRPDNEPARLRSVAENLAAEAAAFVRGRRAEVFGISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPILGEEGGGPADVTATPSDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHLTDERGRHVLRCTGVDELSMALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLCMVAAGRLDAYYEHGVQVWDCAAGALIAAEAGARVLLSTPRAGGAGLVVVAAAPGIADELLAALQRFNGLEPIPD
What is the function of this protein?
Catalyzes the dephosphorylation of inositol 1-phosphate (I-1-P) to yield free myo-inositol, a key metabolite in mycobacteria.
What are the official names of this protein?
Inositol-1-monophosphatase SuhB, I-1-Pase, IMPase, Inositol-1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: NEK6_MOUSE
Sequence: MAGQPSHMPHGGSPNHLCHALGPAPPPDPQRLPNTLSFRCSLADFQIEKKIGRGQFSEVYKATCLLDRKTVALKKVQIFEMMDAKARQDCVKEIGLLKQLNHPNIIKYLDSFIEDNELNIVLELADAGDLSQMIKYFKKQKRLIPERTVWKYFVQLCSAVEHMHSRRVMHRDIKPANVFITATGIVKLGDLGLGRFFSSETTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLFSLCQKIEQCDYPPLPGEHYSEKLRELVSMCIYPDPDHRPDIVYVHQVARQMHVWTSST
What is the function of this protein?
Protein kinase which plays an important role in mitotic cell cycle progression.  Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis.  Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, TRIP4, RPS6KB1 and histones H1 and H3.  Phosphorylates KIF11 to promote mitotic spindle formation.  Involved in G2/M phase cell cycle arrest induced by DNA damage.  Inhibition of activity results in apoptosis.  May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence (By similarity).  Phosphorylates STAT3 (PubMed:20595392).  Phosphorylates EML4 at 'Ser-144', promoting its dissociation from microtubules during mitosis which is required for efficient chromosome congression (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase Nek6, Never in mitosis A-related kinase 6, NimA-related protein kinase 6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Co- localizes with APBB1 at the nuclear speckles. Colocalizes with PIN1 in the nucleus. Colocalizes with ATF4, CIR1, ARHGAP33, ANKRA2, CDC42, NEK9, RAD26L, RBBP6, RPS7, TRIP4, RELB and PHF1 in the centrosome. Localizes to spindle microtubules in metaphase and anaphase and to the midbody during cytokinesis (By similarity).
Protein: TUSD_ECOSE
Sequence: MRFAIVVTGPAYGTQQASSAFQFAQALIVEGHELSSVFFYREGVYNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGIVDETEAGRLGLASSNLQPGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPHD_MYCBO
Sequence: MPATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI
What are the official names of this protein?
Probable oxidoreductase EphD.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ISCS_PSEPG
Sequence: MKLPIYLDYSATTPVDPRVAQKMADCLLVDGNFGNPASRSHVFGWKAEEAVENGRRQVAELINADPREIVWTSGATESDNLALKGVAHFYQTKGKHIITSKIEHKAVLDTARQLEREGFEVTYLEPGEDGIVTPAMVEAVLRDDTILVSLMHVNNEVGSINDIAAIGELTRSRGVLFHVDAAQSAGKVEIDLQKLKVDLMSFSAHKVYGPKGIGALYVSRKPRVRLEAIIHGGGHERGMRSGTLPTHQIVGMGEAFAIAKQEMVAENARIKALSDRFFKQVSDLEELYVNGSQTARVPHNLNLSFNYVEGESLLMSLKDIAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFSFGRFTTEEEVDYAAQKVCEAVNKLRELSPLWDMYKDGVDISKIEWAAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVDB_PLAKN
Sequence: MEGKKKRPLFFLLVLLLSHKANNVLFERMKGILLLECENEYVKNENGYKLATGHHYMDNDQIERWLQGTDRSRRVKIEENVKYKYNVEELNTKYEQTKGKRINRILKESTYEAQNVADNNYIDDKANGEYKTDNKTNKGEGARNMVMLDYDISGSGHPDGIIDNVVELGTEDEGNFLENSSKGGDHPYRMNRKERMCSGVINQTFLQKNVMRRCNNKRKRGTRDWDCPTKKDVCIPDRRYQLCMKELTNLVNNTKTHSHNDITFLKLNLKEKLTYDAAVEGDLLLKKYNNVYSEDLCKDIKWSLEDFGDIIMGTDMEGIGYSQVVENNLRTVFGTGTKTQLDRKKWWNESKKYIWEATILSVKKKLNGYSAWNCKEDVQINVEPQIYRWIREWGMDYMSELPKEQRKIKEKCDRKLYYTNLRICTMSPCNDSCKLYDQWITRKKKQWDVLSTKFSSVKKGQIIETENITTAYDILKQELNGFNEVMFENEINKRDNVYIDICLCAADEPNKNTQEHLKKLKSAPKLETQRSHSTIQPMSSSGAEKVQGDLAHGNINDAAYKSTTDEAAKGDGQNGNQTVAESNIKGTDNIENEAAKNVDTYKFVTERSADTRGATDITETGEEKLNTSYSGSSEITVKENIPGDGIVKDVSAAVENSENPLETKHKIFEPSKDNSDNSENSGSMEFKATSSNPITEAVESSSAEGQVQEDSAHRSVNTGRDNSTISAATSDDGLSSGDKRVESLTSIENADDGGDPVQGSLWNLLNDPSVGAGGGKSHIKTEENEGSQAEIDGKNVDIAEQRTATITEVQPERPDLSDTDNGNVPRSGNKQNEGATALSGAESLESNESVHKTIDNTTHGLENKNGGNEKDFQKHDFMNNDMLNDQTSSDQTSSDQTSSNQTSSDQTSSNQTSSDQTSSDQISSDQTSSDQTSSNQTSSDQTIDTEEHHRDNVRNPEIKSSEDMSKGDFMRNSNSNELYSHNNLNNRKLNIDQYEHRDVKATREKIILMSEVNKCNNRASLKYCNTIEDRMLSSTCSRERSKNLCCSISDFCLNYFELYPYEFYNCMKKEFEDSSYECFTKGSSTGIGIVYFATGGAFLIILLLFVSKNVASNDYEEEATFDEFVEYSDDIHRTPLMPNHIEHMQQFTPLDYS
What is the function of this protein?
Binds to the human erythrocytes Duffy blood group determinant.
What are the official names of this protein?
Duffy receptor beta form, Erythrocyte-binding protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DNJC9_MOUSE
Sequence: MGLLELCEQVFGTADLYQVLGVRREASDGEVRRGYHKVSLQVHPDRVEEDQKEDATRRFQILGRVYAVLSDKEQKAVYDEQGTVDEDSAGLNQDRDWDAYWRLLFKKISLEDIQAFEKTYKGSEEELNDIKQAYLDFKGDMDQIMESVLCVQYTDEPRIRNIIQKAIESKEIPAYSAFVKESKQKMNARKRRAQEEAKEAELSRKELGLEEGVDNLKALIQSRQKDRQKEMDSFLAQMEAKYCKPSKGGKRTALKKEKK
What is the function of this protein?
Acts as a dual histone chaperone and heat shock co-chaperone (By similarity).  As a histone chaperone, forms a co-chaperone complex with MCM2 and histone H3-H4 heterodimers; and may thereby assist MCM2 in histone H3-H4 heterodimer recognition and facilitate the assembly of histones into nucleosomes (By similarity).  May also act as a histone co-chaperone together with TONSL (By similarity).  May recruit histone chaperones ASF1A, NASP and SPT2 to histone H3-H4 heterodimers (By similarity).  Also plays a role as co-chaperone of the HSP70 family of molecular chaperone proteins, such as HSPA1A, HSPA1B and HSPA8 (By similarity).  As a co-chaperone, may play a role in the recruitment of HSP70-type molecular chaperone machinery to histone H3-H4 substrates, thereby maintaining the histone structural integrity (By similarity).  Exhibits activity to assemble histones onto DNA in vitro (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily C member 9.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Note=Predominantly nuclear. Translocates to the cytoplasm and membrane after heat shock.
Protein: ORC5_SCHPO
Sequence: MHLYQLEDELKKNVFCREDQIKKLSCLLFNKDCRVPSIVLYGVASTAKTFLLRTAFDLSKEENVWINLQDCFTVAHFWYRILIKVGVDKDIALKKGINISGFIYLLEQAMSKRDYHTFLVLDQIDDFAEASTILFSQLAQLPIVANIPNLSIIFVLHSHPAQYLGTLSIAVIFFPQYTQAEILEICQKTPPNLDFLDRSGDSVFEDEIELSVWMQYCSFLWSVFGVQCLNDYRSFRSVLDRYWPKFIQPIVEGDIHPADYAQLHKLAKNFLVSDATVTKRLHIINPTEIKNLLDSKSINLSLVSKYLLVSAFLASYNPSRLDAQFFSFSKTSKRRGRKRKQIQDEGVLFSKIPRTAGSKGRSAVKISQLTLGPKPFEVERLIAIYYAISSPVEKVLTADVFVQIATLASLKMILSASKGVLRSLDSPRYIVNVSREYVLKIADSLSFPLDSYLAG
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  It has a role in both chromosomal replication and mating type transcriptional silencing.  ORC binds to multiple sites within the ars1 origin of DNA replication in an ATP-independent manner.
What are the official names of this protein?
Origin recognition complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the ORC5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL22_PASMU
Sequence: METIAKHRYARTSAQKARLVADLIRGKKVAAALEILTFTNKKAAALVKKVLESAIANAEHNDGADIDDLKVAKIFVDEGPSMKRVMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.