PharMolix/UniProtQA huggingface dataset:
Protein: Y2386_SHEFN
Sequence: MAFDKKLLEIVACPVCKGKLDYDKESQQLICKFDKLAYPITEGIPVLLENRATAIVTE
What are the official names of this protein?
UPF0434 protein Sfri_2386.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: DCTA_STRM5
Sequence: MHIPTAAPAPAKPLPIYRQLYFQVIVAIVLGAILGHYEPLVGEKMKPLGDAFINLVKMIIAPVIFLTIVTGIASMTHLRTVGRVFAKAMAYFLFFSTLALIVGMIVAHVVQPGAGMNINPAELDQTAVHSYVEKSHDLTLVGFLMDIIPKTLVSAFVDGNILQVLFIAVLFGIALASVGEKGKPILNFLEALVAPVFKLVHILMKAAPIGAFGAIAFTIGKYGVGSLVNLAWLVGSFYLTAFLFVAVILGVVCRLCGFSVFKLARYLKAELLLVLGTSSSESALPSLMEKMERAGCSKSVVGLVVPTGYSFNLDGTNIYMTLAALFIAQATNTELTLGHQIALLLVAMLSSKGAAGVTGAGFITLAATLAVVPEVPVAGMALILGVDRFMSECRSLTNFIGNAVATVVVSRWEGALDRNRLQLALDGRESELPPPIDVVPEALPAKG
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UB22B_XENLA
Sequence: MSPAGCSHVNSFKVENWRQNLRVIYQCFVWSGTPETRKRKAKSCVCHMCGAHLNRLHSCLYCVYFGCFTKKHIHEHAKNKRHNLAIDLLYGGIYCFMCQDYIYDKDMEQVAKEEQRKAWKLQVFSPALVSPYQYTMTGVGEKYSTWEPTKRELELLQHNPKRRKITTNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHKCEMQSPNSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSDAGVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMMPFMASSKESRMNGQYQQPSDSLHNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVIDSEGYLLFYHKQFLEYE
What is the function of this protein?
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA.  Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator.  Recruited to specific gene promoters by activators, where it is required for transcription (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 22-B, Deubiquitinating enzyme 22-B, Ubiquitin thioesterase 22-B, Ubiquitin-specific-processing protease 22-B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. UBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: QUEA_METCA
Sequence: MLKSEFHYDLPQNLIAQSPLPERSASRLLCLDGATGALEDKSFRDIEKLLRPGDLLVFNDTRVLPARLFGRKETGGAVEILLERLLGERLMLAHVRASKAPRPGTWLALEAEHRVRVVERDGDLFLLELAGEEPLQTVLEQIGHMPLPPYITRPDTSADLERYQTVYATRPGAVAAPTAGLHFDTELLGRLRGAGIDMARVTLHVGAGTFQPVRTENLEDHRMHAEYCEVGPEVVKAVERARGRGGRVVAVGTTSMRSLETAASGGSLRTFSGETRLFIKPGFRFNCVDALVTNFHLPESTLLVLVCAFAGHRETLAAYRHAIAQAYRFFSYGDAMFVTPNEPAANR
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F210A_BOVIN
Sequence: MQWNVPKTVFRLAHRTCMEPHKAGLLGHCQNMKGPLLLYTLESRVVVVQGPQKRWLHLPTAQCVAKERKPFTAVQSQPGVFHHKQWEQDILSKRVLSSSATSSGPPSEKKEDPDPLQDRSISLYQRFKKTFRQYGKVLIPVHLITSAVWFGTFYYAAMKGVNVVPFLELIGLPDSIVNILKNSQSGNALTAYALFKIATPARYTVTLGGTSFTVKYLRSRGYMSTPPPVKEYLQDKMEETKELLTEKMEETKDRLTEKLQETKGKVSLKKKVE
What is the function of this protein?
May play a role in the structure and strength of both muscle and bone.
What are the official names of this protein?
Protein FAM210A.
What is the protein family that this protein belongs to?
Belongs to the FAM210 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Mitochondrion. Cytoplasm.
Protein: PEPT2_LACLC
Sequence: MKYEKLLPRFLEYVKVNTRSDENSTTTPSTQALVEFAHKMGEDMKALGLKDVHYLESNGYVIGTIPANTDKKVRKIGLLAHLDTADFNAEGVNPQILENYDGESVIQLGDTEFTLDPKDFPNLKNYKGQTLVHTDGTTLLGSDDKSGVAEIMTLADYLLNINPDFEHGEIRVGFGPDEEIGVGADKFDVADFDVDFAYTVDGGPLGELQYETFSAAGAVIEFQGKNVHPGTAKNMMVNALQLAIDYHNALPEFDRPEKTEGREGFFHLLKLDGTPEEARAQYIIRDHEEGKFNERKALMQEIADKMNAELGQNRVKPVIKDQYYNMAQIIEKDMSIIDIAKKAMENLDIAPIIEPIRGGTDGSKISFMGLPTPNLFAGGENMHGRFEFVSVQTMEKAVDTLLEIIRLNNEVAK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, L6PepTR, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX2_MACFA
Sequence: MAAEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPKPTEVGLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHASVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREEIEEWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA
What is the function of this protein?
Involved in several stages of intracellular trafficking.  Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex.  The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling.  The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC).  Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity.  Required for retrograde endosome-to-TGN transport of TGN38.  Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (By similarity).
What are the official names of this protein?
Sorting nexin-2.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Note=Colocalized with SORT1 to tubular endosomal membrane structures called endosome-to-TGN transport carriers (ETCs) which are budding from early endosome vacuoles just before maturing into late endosome vacuoles. Colocalized with F-actin at the leading edge of lamellipodia in cells in a KALRN-dependent manner (By similarity).
Protein: CP2J6_MOUSE
Sequence: MLAATGSLLATIWAALHPRTLLVAAVTFLLLADYFKNRRPKNYPPGPWGLPFVGNIFQLDFGQPHLSIQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVFRNWEKLKLFVSCMIDDHRKDWNPDEPRDFIDAFLKEMTKYPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLENGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPINEKLSPKFRNGLTLSPVSHRICAVPRQ
What are the official names of this protein?
Cytochrome P450 2J6, Arachidonic acid epoxygenase, CYPIIJ6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: MED29_HUMAN
Sequence: MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDNGQKSSDGPIQRFDKCLEEFYALCDQLELCLRLAHECLSQSCDSAKHSPTLVPTATKPDAVQPDSLPYPQYLAVIKAQISCAKDIHTALLDCANKVTGKTPAPPAGPGGTL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 29, Intersex-like protein, Mediator complex subunit 29.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 29 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSSA_XENTR
Sequence: MSGGLDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVCVISSRNTGQRAVLKFASASGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNIPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKATTKEEYQGEWTAPVAEFPQAEVADWSEGVQVPSVPIQQFPAERPEIPAAKPAAEDWSSQPASTDDWSAAPTAQASEWTGTTTEWS
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Also functions as a cell surface receptor for laminin.  Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.  May play a role in cell fate determination and tissue morphogenesis.
What are the official names of this protein?
40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Laminin receptor 1, LamR, Laminin-binding protein precursor p40, LBP/p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus. Note=67LR is found at the surface of the plasma membrane, with its C-terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus.
Protein: ELOA1_YEAST
Sequence: MKSLQTLCEISLMRNHSNIQSVSNVPYHLLKRILQKVKIPQLLKLEKSNVLLIFDDDELWLEFLRQDFPTNVHEQFVSKRDIICKYYFDFVKENDIELYHSNQDLLKSCVRQSVVKDIRNNKYRIPYRMLYSKYQQEVEKKQEESAERLRLEMQKLQQEREKKQTIVVDHTVYFKKRNTKKTTRLHNEPHSQLYMKSLKDHESRLKHFKDGGFNIAKRHAQRVAFGGQAGGQSSSPKKGPLSIKPEPVKVNRQMDNVTAEKKDVTQPITPVKKRRSESPSIFLNRKKPALFRPTPKTNAAGSRPHTTAITNDHRTTSHPYPHKDVVTSISSVTANPVTKGHKKKKSGIFVRNAGSDGDSFPHVTATGPTTRPYIYEPRK
What is the function of this protein?
As part of the CRL3 E3 ubiquitin ligase complex; polyubiquitylates monoubiquitylated RNA polymerase II subunit RPO21 to trigger its proteolysis; plays a role in global genomic repair.
What are the official names of this protein?
Elongin-A.
What is the protein family that this protein belongs to?
Belongs to the ELA1 family.
Protein: MOAA_ECODH
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFARLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVASWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RL20_STREM
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVNDAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PA2AA_AUSSU
Sequence: MYPAHLLVLLAVCVSLLGAASIPPQPLNLVQFSYLIQCANHGSRATWHYTDYGCYCGKGGSGTPVDELDRCCKIHDDCYGEAEKKGCYPKMSAYDYYCGENGPYCRNIKKECQRFVCDCDVEAAKCFARAPYNDANWNIDTKKRCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits collagen-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Acidic phospholipase A2 S5-32M, svPLA2, ASPLA10, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CSMJ_CHLTE
Sequence: MIIYINDKPCNAKVGDLLLNTAKLNKAHIGYICGGNGICQSCFVYVLEGAECLSEPGEDEKAFISDKLFAEGGRLACRTTIVKEGTIRVLTRAEKFRRIVLGLNVPGFITYAQTIGYNVTNKLPSGVSSIVSRVQSGRLNPVDTIGKIASGLSPASQLVYNNFIEAFPFMQAPVNMVSGVAKSAIDNASGALCTISGGRLHLPGSTCTAHDKPAEAIERITISAK
What is the function of this protein?
Could play a direct role in the oxidation or reduction of the quenching species formed in the chlorosome.
What are the official names of this protein?
Chlorosome protein J.
What are the subcellular locations of this protein?
Chlorosome.
Protein: Y3264_ARATH
Sequence: MLPKKPIFSSTEQHRFDETRWVINVQKSLDAELEEHDLEEVTVSIFNVPKALMCSHPDSYTPHRVSIGPYHCLKPELHEMERYKLMIARKIRNQYNSFRFHDLVEKLQSMEIKIRACYHKYIGFNGETLLWIMAVDSSFLIEFLKIYSFRKVETLINRVGHNEILRDIMMIENQIPLFVLRKTLEFQLESTESADDLLLSVLTGLCKDLSPLVIKFDDDQILKAQFQECNHILDFLYQMIVPRIEEEELEEDDEENRADENGGNRAIRFMDEIKHQFKRVFASRPADLILRFPWRIISNLPGFMALKLSADYLFTRQENEATTTRQESVSILDIEKPPLVEELTIPSVSDLHKAGVRFKPTAHGNISTVTFDSNSGQFYLPVINLDINTETVLRNLVAYEATNTSGPLVFTRYTELINGIIDSEEDVRLLREQGVLVSRLKSDQEAAEMWNGMSKSVRLTKVGFLDKTIEDVNRYYTGRWKVKIGRLVEVYVYGSWQILAFLAAVLLLMLVSLQLFSLVFSSFLRFRAG
What are the official names of this protein?
Putative UPF0481 protein At3g02645.
What is the protein family that this protein belongs to?
Belongs to the UPF0481 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CYSP1_MAIZE
Sequence: MAHRVLLLLSLASAAAVAAAVDAEDPLIRQVVPGGDDNDLELNAESHFLSFVQRFGKSYKDADEHAYRLSVFKDNLRRARRHQLLDPSAEHGVTKFSDLTPAEFRRTYLGLRKSRRALLRELGESAHEAPVLPTDGLPDDFDWRDHGAVGPVKNQGSCGSCWSFSASGALEGAHYLATGKLEVLSEQQFVDCDHECDSSEPDSCDSGCNGGLMTTAFSYLQKAGGLESEKDYPYTGSDGKCKFDKSKIVASVQNFSVVSVDEAQISANLIKHGPLAIGINAAYMQTYIGGVSCPYICGRHLDHGVLLVGYGASGFAPIRLKDKPYWIIKNSWGENWGENGYYKICRGSNVRNKCGVDSMVSTVSAVHASKE
What is the function of this protein?
Involved in the degradation of the storage protein zein.  May play a role in proteolysis during emergencies.
What are the official names of this protein?
Cysteine proteinase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: TRMB_HUMAN
Sequence: MAAETRNVAGAEAPPPQKRYYRQRAHSNPMADHTLRYPVKPEEMDWSELYPEFFAPLTQNQSHDDPKDKKEKRAQAQVEFADIGCGYGGLLVELSPLFPDTLILGLEIRVKVSDYVQDRIRALRAAPAGGFQNIACLRSNAMKHLPNFFYKGQLTKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGLVYTITDVLELHDWMCTHFEEHPLFERVPLEDLSEDPVVGHLGTSTEEGKKVLRNGGKNFPAIFRRIQDPVLQAVTSQTSLPGH
What is the function of this protein?
Catalytic component of METTL1-WDR4 methyltransferase complex that mediates the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs) (PubMed:12403464, PubMed:31031083, PubMed:31031084, PubMed:36599982, PubMed:36599985).  Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in a large subset of tRNAs that contain the 5'-RAGGU-3' motif within the variable loop (PubMed:12403464, PubMed:34352207, PubMed:34352206, PubMed:36599982, PubMed:36599985).  M7G46 interacts with C13-G22 in the D-loop to stabilize tRNA tertiary structure and protect tRNAs from decay (PubMed:36599982, PubMed:36599985).  Also acts as a methyltransferase for a subset of internal N(7)-methylguanine in mRNAs (PubMed:31031084).  Internal N(7)-methylguanine methylation of mRNAs regulates translation (PubMed:31031084).  Also methylates a specific subset of miRNAs, such as let-7 (PubMed:31031083).  N(7)-methylguanine methylation of let-7 miRNA promotes let-7 miRNA processing by disrupting an inhibitory secondary structure within the primary miRNA transcript (pri-miRNA) (PubMed:31031083).  Acts as a regulator of embryonic stem cell self-renewal and differentiation (By similarity).
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, Methyltransferase-like protein 1, mRNA (guanine-N(7)-)-methyltransferase, miRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCIB_SHEFN
Sequence: MKQLLDFLPLVIFFAVYKFYDIYAATGVLIAATAIQLVITYLIYKHIEKMHLATFAMVTVFGSLTLFFHDDAFIKWKVSIVYALFAIGLIASQIMGKSALKSMLGKEMKVDDRIWAQVTWYWVGFFVLCSFANIYIAFNLPLETWVNFKVFGLTALTLINTVITVVYLYKNMQDDNSQPTDNQ
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AGAP7_HUMAN
Sequence: MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAEDRMAGAPMAAAVQPAEVTVEVGEDLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVHFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSKSDGLSKDMDTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDECV
What is the function of this protein?
Putative GTPase-activating protein.
What are the official names of this protein?
Putative Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7, AGAP-7, Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7 pseudogene, Centaurin-gamma-like family member 4.
What is the protein family that this protein belongs to?
Belongs to the centaurin gamma-like family.
Protein: KTNB1_CHICK
Sequence: MAAAVVTKTAWKLQEIVAHSSNVSSLVLGKSTGRLLATGGDDCRVNVWSVNKPNCVMSLTGHTTPIESLQISAKEELIVAGSQSGSIRVWDLEAAKILRTLLGHKANICSLDFHPYGSFVASGSLDTDIKLWDVRRKGCIFKYKSHTQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKVMFEFTGHSGPVNVVEFHPSEYLLASGSSDRTIRFWDLEKFHVVSCIEEEATPVRCILFNPDGCCLYGGFQDSLRVYGWEPERCFDVVVVNWGKVADLSVCHNQLIGVSFAQSTVSSFVVDLSRVTKSGSVPHGLLRNNELLAQPTPTGSSLRRSYDRPSTSCSKPQRVKHSSESERRSPSSEEDRDEKESKAEIQNPEDYKEIFQPRNAISRTPPHINEPFPAPPEDEPITAKEAVKPNQPVEVQTPLPKQELPETFQRPPIASSTPMPRAEPSVIPAARNEPIGLKASDFLPALKNQSQAELTDEEIMSQIRKGHKTVCMVLTSRHKNLDTVRAVWSTSDMKNSVDAAVATNDLSVVVDLLNIVNQTASLWKLDLCTVVLPQIEKLLQSKYESYVQTGCTSLKLILQRFLPLITDILAAPPSVGVDITREERLHKCRLCYKQLKNISNIVKNKSGLSGRHGSAFRELHLLMAVLE
What is the function of this protein?
Participates in a complex which severs microtubules in an ATP-dependent manner.  May act to target the enzymatic subunit of this complex to sites of action such as the centrosome.  Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
What are the official names of this protein?
Katanin p80 WD40 repeat-containing subunit B1, Katanin p80 subunit B1, p80 katanin.
What is the protein family that this protein belongs to?
Belongs to the WD repeat KATNB1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.
Protein: BGAL_SACS2
Sequence: MYSFPNSFRFGWSQAGFQSEMGTPGSEDPNTDWYKWVHDPENMAAGLVSGDLPENGPGYWGNYKTFHDNAQKMGLKIARLNVEWSRIFPNPLPRPQNFDESKQDVTEVEINENELKRLDEYANKDALNHYREIFKDLKSRGLYFILNMYHWPLPLWLHDPIRVRRGDFTGPSGWLSTRTVYEFARFSAYIAWKFDDLVDEYSTMNEPNVVGGLGYVGVKSGFPPGYLSFELSRRAMYNIIQAHARAYDGIKSVSKKPVGIIYANSSFQPLTDKDMEAVEMAENDNRWWFFDAIIRGEITRGNEKIVRDDLKGRLDWIGVNYYTRTVVKRTEKGYVSLGGYGHGCERNSVSLAGLPTSDFGWEFFPEGLYDVLTKYWNRYHLYMYVTENGIADDADYQRPYYLVSHVYQVHRAINSGADVRGYLHWSLADNYEWASGFSMRFGLLKVDYNTKRLYWRPSALVYREIATNGAITDEIEHLNSVPPVKPLRH
What are the official names of this protein?
Beta-galactosidase, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: RL24_HAEDU
Sequence: MAAKIRQNDEVIVLAGKDKNKRGKVTKVLPNGKVIVEGINLITKHEKPVPALGKAGGLVKKEAAIDVSNVAIFNPTTNKADRVGFRFEDNKKVRFFKSNNEII
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PNP_BURM9
Sequence: MSLFNKIVKEFQWGQQKVRLETGEIARQASGAVIVDIEDTVVLATVVGAKSAKPGQDFFPLTVDYIEKTYSAGKIPGGFFRREGRPSEHETLTSRLIDRPLRPLFPEGFYNEVQVVIHVLSVNPEIPADIPALIGASAALAVSGLPFNGPVGAARVAYVNNEYVLNPTREQIKASRLDLVVAGTERAVLMVESEADQLPEDVMLGAVVFGHEQMQTAIDAIHELVREGGKPEWDWQPAPKDEALNARVTELAQPELLAAYQIRDKQARLTKLKEVYAATSAKLEEEAVAAGTVAADKATVGNILFDLEAKIVRGQILNGEPRIDGRDTRTVRPIEIRTGVLPRTHGSALFTRGETQALVVATLGTKGDEQIIDALEGEYRERFMLHYNMPPFATGETGRVGSPKRREIGHGRLAKRALVACLPSADEFGYSIRVVSEITESNGSSSMASVCGGCLALMDAGVPMKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTADGVTALQMDIKIQGITKEIMQVALAQAKEGRMHILGKMKDAVAGANTQLSEFAPRMITIKINPEKIRDVIGKGGSVIRALTEETGTTIDISDDGVVTIASTNSEGMAEAKKRIENITAEIEVGHVYEGTVLKLLDFGAIVNLLPGKDGLLHISEIVNERVKDINDYLKEGQQVKVKVIQTDEKGRVRLSAKALLNEAAAQADTPPQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MESH1_XENTR
Sequence: MSSDAALILEAANFAAEKHKQQRRKDPEKTPYINHPLGVARILSHEGGITDTAVLQAALLHDTVEDTNTTFEEIELHFGQDVRNIVEEVTDDKTLPKMERKRLQMEHAPHCSQKAKLVKLADKLYNLRDLKRCTPEGWSEQRVQEYFQWASEVVKGLRGTNSILEGKLDHMFMDQGIAV
What is the function of this protein?
ppGpp hydrolyzing enzyme involved in starvation response.
What are the official names of this protein?
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, HD domain-containing protein 3, Metazoan SpoT homolog 1, MESH1, Penta-phosphate guanosine-3'-pyrophosphohydrolase, (ppGpp)ase.
What is the protein family that this protein belongs to?
Belongs to the MESH1 family.
Protein: RNH2_CHLL3
Sequence: MMPMDTVREYLLWNDFLRVCGIDEAGRGPLAGPVVAAAVVFPRWFSPDEGILRRLNDSKKLTPSLRRELAPAIREEAECWAVEAVDHETIDRINILRATMLAMNRAAESLPRQPDLLLIDGNRFTPNIPVPYQTIVGGDALVFSIAAASVLAKTERDRMMEEYAERYPEYGFERNAGYGTREHVEAIRRHGRSPIHRTSFRLRQLGEK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.