PharMolix/UniProtQA huggingface dataset:
Protein: ACCA_PROM5
Sequence: MPRRYLLDFEKPLVELEKQIEQIRELARDSEVDVSQQLLQLETLATRRREEIFRSLTPAQKIQVARHPQRPSTLDFIQMFCDDWIELHGDRNGGDDMALIGGLGSVNNQPVLLLGHQKGRDTKENVVRNFGMAKPGGYRKALRLMQHADRFSLPILSFIDTPGAYAGLSAEEQGQGEAIARNLREMFGFKVPIIATIIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAAKAPEAATALKITGKDLLELGVIDEVLSEPAGGNNWAPIEAGNTLKASIERHLSELLKMSKEELLEQRYSKFRVLGKFIESSSVEEIKEEFTQKKE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_ENT38
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMSIPERVSLTMAMRDSGSVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLEAIPGFDIFPNDTRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTFELSAALAEAIVGVSNGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEIFGRMVAAQKGPNDFVENYAKYLPTAMLSKAVYADTEGFVSAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDSVDGQRPLAVIHAKDENSWQEAAKAVKAAIQLDDKAPETTPTVYRRITD
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: RIMP_PROMT
Sequence: MSNQTVSELKVLTAKSATNYGFDVTDFKMFTHLNPLSIQVNIRHKNPDKKVTIDDCSILSQYIDEAIQGSSILDQPFNLEISSEGIGDFLTEEKDFQTFKGFPVEVSYQDLKKIEQQINGLLLKRTDNELHINQKGKTQRIPVEDVIQVRLATPSG
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DVL17_ARATH
Sequence: MGQCSSATKMRRKRKREEECCRESMERRNKGCLAMVKERRSRFYIARRCILMLLCWHKYANS
What is the function of this protein?
Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
What are the official names of this protein?
Small polypeptide DEVIL 17, Small polypeptide ROTUNDIFOLIA LIKE 6, Small polypeptide ROT-FOUR-LIKE 6.
What is the protein family that this protein belongs to?
Belongs to the DVL/RTFL small polypeptides family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YELB_SCHPO
Sequence: MNTTKRILAIQSSVCHGYVGNRAATFPLQLLGWDVDAIPTVELSNHAGYPIVKGRTLSAEQILDLYKGVSAANPSGYECLLTGYARGIGSVKAIMEIVRSVKSKNKKAFWVFDPVLGDNGRLYVEESIIPLYREMLPFADLITPNGFEAEILSGMRINSIDTAFKCVECLQQKYKVPRVVISSFVVEENGVEKLYCIGSSIYSKSFFVLIPVIPGIFRGTGDLFTALMAAHIAESPDCTESLASIKEDKLKKSVEMALSSVHEVIQKTADRISALGVEEYHPAYAELCIVNSQNSIIAPSKLFEAVYYY
What is the function of this protein?
Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
What are the official names of this protein?
Putative pyridoxal kinase C6F6.11c.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CTAA_NITMU
Sequence: MQFVQTSTLPQKTDQKFAVQKPIAIWLFVCCALVFAMVVVGGVTRLTDSGLSIVEWQPLVGTVPPLSQNDWDELFEKYHQTPQYKKVNLGMSLEEFKTIFWWEYFHRLLGRVIGLAFFIPFLYFLMKKAVDRPLGLKLSGIFLLGALQGGMGWYMVKSGLVDNPHVSQYRLTAHLGLAFAIYAAMFWVALDLLNPGRGLSANSGLRGLLNFSTMLSALVFIMVLSGGFVAGIRAGLAYNTFPLMDGHFIPPELFMLEPWYRNFFDNMTTVQFDHRLIAWTLAILVPIFWLKSRAVPLSGSARLACTLLLIMLAVQITLGISTLLLVVPLTLAAAHQAGALLLFTAALWVNHELRRQ
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL33_SHEON
Sequence: MAKAKGNREKIKLVSTAKTGHFYTTEKNKRNMPEKMEIKKFDPVIRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: CARP6_CANAL
Sequence: MLLKNILSVLAFALLIDAAPVKRSPGFVTLDFNVKRSLVDPDDPTVESKRSPLFLDLDPTKIPVDDTGRNDGVDKRGPVAVKLDNEIITYSADITVGSNNQKLSVIVDTGSSDLWIPDSKAICIPKWRGDRGDFCKNNGSYSPAASSTSKNLNTRFEIKYADGSYAKGNLYQDTVGIGGASVKNQLFANVWSTSAHKGILGIGFQANEATRTPYDNLPISLKKQGIIAKNAYSLFLNSPEASSGQIIFGGIDKAKYSGSLVELPITSDRTLSVGLRSVNVMGRNVNVNAGVLLDSGTTISYFTPSIARSIIYALGGQVHFDSAGNKAYVADCKTSGTVDFQFDKNLKISVPASEFLYQLYYTNGKPYPKCEIRVRESEDNILGDNFMRSAYIVYDLDDKKISMAQVKYTSESNIVAIN
What is the function of this protein?
Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors.  These enzymes supply the fungus with nutrient amino acids as well as are able to degrade the selected host's proteins involved in the immune defense.  During infection, plays an important role in penetration into deeper tissues and interaction with host defense.  Activates host systemic immunity and induces host inflammatory cytokine production in a proteolytic activity-independent way.  Contributes to corneal pathogenicity.  Moreover, acts toward human hemoglobin though limited proteolysis to generate a variety of antimicrobial hemocidins, enabling to compete with the other microorganisms of the same physiological niche using the microbicidal peptides generated from the host protein.
What are the official names of this protein?
Candidapepsin-6, ACP 6, Aspartate protease 6, Secreted aspartic protease 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y103_STRA5
Sequence: MILDYNKLKQETKAIVVDIIERSALKKGQIFVLGLSSSEVSGGLIGKNSSSEIGEIIVEVILKELHSRGIYLAVQGCEHVNRALVVEAELAERQQLEVVNVVPNLHAGGSGQVAAFKLMTSPVEVEEIVAHAGIDIGDTSIGMHIKRVQVPLIPISRELGGAHVTALASRPKLIGGARAGYTSDPIRKF
What are the official names of this protein?
UPF0340 protein SAG0103.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: HIS1_STACT
Sequence: MLTVALSKGRLLKDFIKFLERNNNHVWADAIIHRERKLQITADSIKFILVKGSDVPTYVEEGIADIGITGSDILKERPNRNINNYIDLPFGECHFSVAAKPNVTNIQRVATTYVKTTRDYFNQKGTDISIIQLSGSVELAAVVDMVDAIVDIVQTGTTLKSNGLEEREQIGEINARLITNKHSFFSKSKAIENFIQQLGVSIHAQ
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_SHIBS
Sequence: MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSETKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: HFLX_ACIC5
Sequence: MARRAASADLDSLDLDSLGDQEPGAAEKGGSDDAFESGVAEFRELVLSAGAEIAAEVQQRRGRADAATLIGSGKVEEVRAVAESSHADVIVFGQNLTPTQLRNLENALPGRVIDRTQLILDIFARHARTREGMLQVELAQLEYMLPRLTGRGREMSRLGGGIGTRGPGETQLETDRRRIQRRISTLKGELESVRRIRSQQRQRREAVPVPTVALVGYTNAGKSTLFNALTGAGVLASSRMFATLDPKLRAIVLPSRRKVLLSDTVGFIRDLPPTLISSFRATLEEVQKAEVLLHVQDCSSATREEHRAEVKHVLAELGAGDKPQIEVLNKVDLLSPEEQEGLRSGHGRPMAISARTGMGLEDLLERIDEALQADPMVEARLRVPQSEGEVIAAIEAGGVIRNREFEGNLVFLKVSAPASLIGRFRRFATLPK
What is the function of this protein?
GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
What are the official names of this protein?
GTPase HflX, GTP-binding protein HflX.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=May associate with membranes.
Protein: H8A19_CYRHA
Sequence: MVNMKALMFLTFAGLVLLFVVCYASESEEKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCSGYVCSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1a 19, U3-TRTX-Hhn1a, Hainantoxin-VIII.19, HNTX-VIII.19, Peptide F4-27.90.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VLTF1_FOWPN
Sequence: MSLRIKIDKLRQLVTYFSEFSEEVSINIDVKSNVLYIFATLGGSINIWTIVPLNSNVFYNGVENTVFNLPVLKVKNCLCSFHNDAVVSITADHDNNTVTLSSHYTVSIDCNNEQIPHSTGTSISLGIDQKKSYIFNFHKYEEKCCGRTVFHLDMLLGFIKCISQYQYLNICFDDKKLLLKTPGTRDTFVRSYSMTEWSPTLQNYSFKIAIFSLNKLRGFKKRVLVFESKIVMDTEGNILGLLFRDRIGTYKVNVFMAFQD
What is the function of this protein?
Associates with RNA polymerase to initiate transcription from late gene promoters.
What are the official names of this protein?
Late transcription factor 1, VLTF-1.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae VLTF-1 family.
Protein: ILVD_BRUA2
Sequence: MPPYRSRTTTHGRNMAGARGLWRATGMKDEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIESAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKVVWEDSVKKLDLVDAMVAAADDHYTDEQVKAIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHADRKRLFVEAGHLIVDLARRYYEQDDESVLPRSIATFSAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMADIDRLSRRVPVLCKVAPAVSSVHMEDVHHAGGIMGILGQLDNAGLLTTSIPTVHSETLAKALDHWDVTRTNSEMVHKFYSAAPGGVPTQVAFSQERRFDKVDTDREKGVIRSKEHAFSQDGGLAVLYGNLAEDGCIVKTAGVDDSILKFSGPARIFESQDSAVLGILNGKIKPGDIVLIRYEGPRGGPGMQEMLYPTSYLKSKGLGKACALITDGRFSGGSSGLSIGHVSPEAAEGGTIGLVREGDIIDIDIPNRKIHLAVDDATLAERRAEQDAAGWKPAEERKRKISTALKAYAAMATSAARGAVRKLPD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: DGTP_ECO8A
Sequence: MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: 14337_ORYSJ
Sequence: MAPSDDLVYMAKLAEQAERYDEMVEAMNSVAKLDEGLTKEERNLLSVGYKNLIGAKRAAMRIIGSIELKEETKGKESHVRQTAEYRRKVEAEMDKICCDVINIIDKYLIPHSSGAESSVFYYKMKGDYYRYLAEFKTGTEKIEVSELSLNAYETASKTAQTDLTPTDPIRLGLALNISVFYCEIMNSPDKACQLAKNAFDEAVAELPSLSEENYKDSTLIMQLLRDNLALWNSDMADDADDIRERTDTTGAKGDPAA
What is the function of this protein?
Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.
What are the official names of this protein?
14-3-3-like protein GF14-G, G-box factor 14-3-3 homolog G.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: APAH_PARP8
Sequence: MTASTASAPLAFGDLQGCRTQFQQLLAKAAPPADAPLWFAGDLINRGGESLAMLRDIIALGDRAVPVLGNHDLHLLSVSAGIRKSKKGDTIDEILAAPDADDMLHWIRHRPLAHYENGMLLVHAGVLPQWDVDLTLELADELQRALRAPGWKETLAGLYGNEPNRWKPGLKGIDRLRLTCTALTRMRFCNADGVMDFSSSGGIGSAPAGFMPWFDVPGRKTEEITVVFGHWAALGLLIRDNLIGLDSGCVWGEQLSAVRLAQSAAERTVTQVECEGCRADVH
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: RL25_RUEST
Sequence: MANEIPDLECQVRAGTGKGAARAARRANLVPGVVFGGDADPLAIQIPYNVLLKRLKAGRFKSTLFNLKVEGHDDVRVICRDVQRDVVKDLPTHFDLMRLRRTSKINLFIPVEFINEEECVGLKRGGVLTVVRAEVELVVTAGDIPEKLTVDLTGKAIGDVIHISDVTLPEGSKPTIDRDFVIANISAPSGLKSADDEAEGEDAEEAAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PCNA_XENLA
Sequence: MFEARLVQGSILKKVLEALKDLIDEACWDITSSGISLQSMDSSHVSLVQLTLRSDGFDTYRCDRNQSIGVKMSSMSKILKCAASDDIITLRAEDNADTVTMVFESPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVIKMPSGEFARICRDLSQIGDAVVISCAKDGVKFSASGELGTGNVKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSPTVILSMSADIPLVVEYKIADMEHVKYYLAPKIEDEEAS
What is the function of this protein?
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
What are the official names of this protein?
Proliferating cell nuclear antigen, PCNA, Cyclin.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMG_STRP1
Sequence: MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKSLVEWNTKINLTAITEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDSLNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELTIPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKKKETPNKYPRKAGLPNKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_BUCAI
Sequence: MAKKIQSYIKLQVSAGAANPSPPIGPALGQKGVNIMEFCKLFNKKTENIEKGLPIPVIITVYSDRSFTFITKTPPASVLLKKLSGIKKGSSKNKSEKIGKINRSQIKEIAIIKNNDMTGSNIENMMRSIEGTAKSMGLIIEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: ARP8_DANRE
Sequence: MTQTDRDAENGRDREKDREKEQQRGVKRPIMPAAVPEPVQEQIQANFIVVIHPGSRTLRLGRATDTLPISVPHVIARRHKHPGQSRYEDKCLLREGLNSADSNEQRQNGLKMVDQVIWSKKMSNGVRRTPVSAEQARLYNRQIRPAVLDPNSKVSWTNTSHHPEYVVGEEALYVNPTDCYSVHWPVCRGRLNLHSGSGGSLSAVMMDLEHIWTHALQKLLQIPLKDLKYYRCILLIPDIYNRQHVKEIVNMLLVKMGFSAVVVHQESVCATFGSGLSSACVVDVGDQKTSVCCVEDGVSHRSSRLCLAYGGSDVTRCFFWLMQRAGFPYRDCQLGNKLDCVLLQQLKESFCHLDQDISGLQDHEFRTRFPDSPVLLYQLRLGDEKLQAPMTLFYPAAFGIVGQRMTSLLHRSQGDAEDPHDEHFLLTTQSKQDQSSKASADRKSFPKPSSFEGESSVCEVSDRSSLGQDLDLGHSQAECLVGGAETEETPSALLSRKTAMSQFEGKALGIDKAILHSIDSCASDETKRKMYSCILVVGGGLLFHGAQEFLQHRILNKMPPSFRCMVESVDVITRPKDTDARVCVWKGGSVLACLDTTQELWIHQREWQRFGVRMLRERAAFVW
What is the function of this protein?
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.  Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex (By similarity).
What are the official names of this protein?
Actin-related protein 8.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP8 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Specifically localizes to mitotic chromosomes.
Protein: RL31_RICCN
Sequence: MKSSIHPEYKKFLIKVGSDVFETMSTHPTGEILMDVDFRKHPAWNKDSGNVVNQSNKSVSDFNKRFSGLSFGSKKEAS
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: KDSA_HAHCH
Sequence: MSTRTVKVGGIDIANDRPFVLFGGMNVLESRDLALQVAESYVKVTQKLGIPYVFKASFDKANRSSINSYRGPGLDEGLRIFEEIKRTFNVPVITDIHEPHQAQPVAEVADIIQLPAFLSRQTDLVAAMARTGCPVNIKKAQFLAPQEMKHILSKCEEAGNDQLILCERGSSFGYNNLVVDMLGFGIMKQFGYPVFFDVTHSLQMPGGLSSSAGGRREQVVQLARSGMAVGLAGLFLEAHPDPDVAKCDGPCALRLSQLEPFLAQMKALDDMVKQFPNIDTA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y137_TREPA
Sequence: MLLEPRVTGCFLSSSEQALPPAIYFPLLLLLRSGARNIVGITSVG
What are the official names of this protein?
Uncharacterized protein TP_0137.
Protein: NGFV_BOTCO
Sequence: EDHPVHNRGEYSVCDSVNVWV
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor Bco12, v-NGF, vNGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL1_THIDA
Sequence: MAVKTYSAGVKEYRQTYWMPEYTPLDTDILACFKITPQAGVDREEAAAAVAAESSTGTWTTVWTDLLTDLDYYKGRAYAIEDVPGDDTCFYAFIAYPIDLFEEGSVVNVFTSLVGNVFGFKAVRALRLEDVRFPIAYVKTCGGPPHGIQVERDVMNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRQRFDFVMEAIQKSERETGERKGHYLNVTAPTPEEMYKRAEYAKEIGAPIIMHDYITGGFCANTGLANWCRDNGMLLHIHRAMHAVLDRNPHHGIHFRVLTKILRLSGGDHLHSGTVVGKLEGDREATLGWIDMMRDSFVKEDRSRGIFFDQDWGSMPGVFPVASGGIHVWHMPALVTIFGDDSVLQFGGGTLGHPWGNAAGAAANRVALEACVEARNKGVAIEKEGKTVLTEAAKNSPELKIAMETWKEIKFEFDTVDKLDVAHK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: EI3F2_DROER
Sequence: MSRNLGMRAKVLIKPLVLFQIIDSYERRPKGDNQVIGTLLGRNKEGHFEITNCFTVPHKEHPEINRIDLDIAYASEILELNMLTYPNERVLGWFCTGKSVSRSASLLHDYYARECGEVQPLHLVVDATLKSQRLSTRLYCAVEIGVPGGTKGLMFSLVPLEISNGNSDLVALRSIEKQSLQQGTKQLDRFIPELVQVVDATRDIQQRLDLVLRYIKDVLDRKRKPDNVVGRALHAALTAVPVMDPDKFRLMFNTNLRDMLMAITLSTMIKTQLEISEKLSCMQDQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F-2, eIF3f-2, Eukaryotic translation initiation factor 3 subunit 5-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHDC_HALH5
Sequence: MNEAAKTLDGWYCLHDFRTINWAELKTLSTEERQQIINEFLDLMEKWNDTEAQGEGSHAVYTIVGQKADVMLMILRPSMEELNEIETAFNKSRFAEFTVPAYSYVSVVELSNYMAGDSDDDPYQNPHVRARLYPQLPKAKHVCFYPMDKRRQGDDNWYMLPMDQRRELMKSHGMIGRSYAGKVKQIITGSVGFDDWEWGVTLFADDVLQFKKLVYEMRFDEVSARYGEFGSFFVGNLLTAEGIPSYFYV
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: RS12_MICLC
Sequence: MPTIQQLVRKGRSPKVVNTKAPALQGNPMRRGVCTRVYTTTPKKPNSALRKVARVRLNGGIEVTAYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYKIVRGALDTQGVKNRGQARSRYGAKKEKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.