PharMolix/UniProtQA huggingface dataset:
Protein: MYL5_HUMAN
Sequence: MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
What are the official names of this protein?
Myosin light chain 5, Myosin regulatory light chain 5, Superfast myosin regulatory light chain 2, MYLC2, MyLC-2.
Protein: KAE1_GIBZE
Sequence: MAFTNKSSYIALGCEGSANKLGIGVILHTPTETKILSNLRDTFVSPPGTGFLPKDTAAHHRAHFVRLAREALAEAKITPADVDCICYTKGPGMGAPLNSVAVAARALSLLWDRPLVGVNHCVGHIEMGRYITGAENPVVLYVSGGNSQVIAYAEQRYRIFGETLDIAVGNCLDRFARTLEISNDPAPGYNIEQLAKKGSKLLDIPYAVKGMDCSFSGILASADALAAQMKAGADFTPEDLCFSLQETVFAMLVEITERAMAHVGSSQVLIVGGVGCNERLQEMMGHMARERGGSVYATDERFCIDNGIMIAHAGLLAYETGFRTSLEESTCTQRFRTDEVFIKWRD
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1, tRNA threonylcarbamoyladenosine biosynthesis protein KAE1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RGL1_YEAST
Sequence: MTHPVISLKPSYNSVIRGCPGLPDTLPRIECQLRVRSNNSLPFKLVKIEIVLKTIEIYFNKNLYSSNNSSFTPFNRPSDPSNGHSDTSNQNISIHYKKNIVLSHPTHDGDDLNNDLIGIDIPLTIGLPDDIKETNYNPKFGKTQTFLDCTVFYTEVGGGSSNKKRNFLYPVNVERYTYLPSPSYFRPINRSNITSPDQKFLISYSIENPCVSMNNDTLKLSISIRLNPFPNNATTPSSNDFDVSTPTLFSTKKKFKSKLKLKSITTQILEYLEILKNQSEFSSTQTTNILQTSVRQVDQIISMNSMIFQFNLKIFTKDKILQSFRSSESSCPETKVLINKIDDIPLQYHSSITTIGQHFNVSHYLSIRFKFNKSLKNFEINHPLIISFWSVSQLPLIENLILQERQTAKFAKKFYKNFGRIKNTSNNNNSSNCLEYPSLPPIIYNFNDPETNNRFNILYSQKDPSRTDPSKLRRVPVIQ
What is the function of this protein?
Regulator of RHO1 signaling that acts as a cofactor required for the efficient localization of the TUS1 GTP exchange factor (GEF) for RHO1 to the bud neck during all phases of cytokinesis (PubMed:22344253).  RHO1 is a key, essential hub protein in the cell wall integrity (CWI) pathway in which activated RHO1-GTP binds directly to and activates multiple different downstream effectors required for cell wall synthesis and actin assembly during cytokinesis (Probable).
What are the official names of this protein?
RHO1 GEF localizing protein 1.
Protein: CH10_LACZE
Sequence: MLKPLGDRVIVEVVEEEEQTVGGIVLANNAKQKPQTGKVVAVGEGALTPEGKRLPMAVKVGDTVLYDKYAGSEVKYEGQDYLVLHEKDIMAIA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS211_RHIEC
Sequence: MQVLVRDNNVDQALRVLKKKMQREGLFREMKARSAYEKPSEKRAREKGEAVRRQRKLARKKLQREGLLPAPKKAVRAR
What are the official names of this protein?
30S ribosomal protein S21 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CT455_HUMAN
Sequence: MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDGMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI
What are the official names of this protein?
Cancer/testis antigen family 45 member A5, Cancer/testis antigen 45-5, Cancer/testis antigen 45A5.
What is the protein family that this protein belongs to?
Belongs to the CT45 family.
Protein: CYSN_SULNB
Sequence: MAKENSKIALDIEGYLKEHENKDMLRFLTCGSVDDGKSTLIGRMLYDSKMIFDDQLSAAEGESRKYGTTGEKLDMALLVDGLQSEREQGITIDVAYRFFATEKRKFIIADTPGHEQYTRNMVTGASTADVAIILIDARKGILTQTRRHSFIVNLLGIEHVIVAINKMDLVDFSEEVFDKISGAYGALADELGIKNTYYIPVSALEGDNVVDRSKRSPWFSGQPLLGLLDSMDISKEPKEEDFRFPVQYVNRPNLDFRGFCGTIAAGLVRTGDEITVLPSGKTTKVKNIVNAGDITEKNRETMTEYAYAPMAVTITTEDEVDISRGDMIVHTKNLPRVSNSLKVMLVWMDETPMEPGKTYDIKRATSVVPGFIEHINYKVDINTYEREQVHRLGLNDIASCKMVLTQPIAADAYETNRLTGSFIVVDRISNDTVGAGMIVGVSRREEDVVKLSAKEYTDAERALNLYVRENFPEWECKVI
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: HUGA_TABYA
Sequence: MKLHQGLVCLSVLILLPTCILGDRKFEVYWNIPTFMCPDQNKTIMDLNKKHGVIQNTEDLFRGDKISLLYHPGAFPAITRNKTTNTLIYENGGVPQAGNLSLHLKLLEKDINEQITDKNFSGLAVIDFELWRPIFRQNGGSLSDYQNLSLKLEKDLHPEFNEDQLRKEAERRIEKFGRSFIKQTLIKAKKLRPKAQWGYYAFPYCFNGRRRYVDTCIPSAKIDNDRILYMFENSDVIYPAVYLQTDLAQKNQTGLVKGRVDEAVRMAKMVKKPAKPPVLVYHRYVFTDTLEYISKENTTAVFKAMKDNGADGVIIWGSSFDLNSKEKCAKFLDYLREVLWPVIDEVKRS
What is the function of this protein?
Hydrolyzes high molecular weight hyaluronic acid to produce small oligosaccharides.
What are the official names of this protein?
Hyaluronidase Tab y 2.0101, Allergen Tab a 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAA_WOLSU
Sequence: MSIQLHDKVSLLILDFGSQYTQLIARRLREYGIYCEIVPYHEKLEAIKAREPKGIILSGGPASVYEEDAFLIDKAVFELGIPVLGICYGMQLMTHYFGGVVAKAEHHEYGKAEVIFDALEGSESKLFEGCHSGKVVWMSHGDKVEKLPEGFTRIAHSTNSPFAAIAHQEKPFYAVQFHPEVVHSEEGALYLKNFALGICGCENDWNMHNFAEEQIKKIQERVKSGKVLCAVSGGVDSSVVAALLYRAIGEKLIPVFVDHGLLRAGEREAVEKMFKENLHVPLITVDASEIFLGKLKGVSDPETKRKIIGETFIEVFDVEAKKHDGIQYLAQGTLYPDVIESVSVKGPSKTIKSHHNVGGLPDWMTFELIEPLRELFKDEVRALGAELGMPREMLMRHPFPGPGLAIRIMGEVNFEDLELLRKADVIMLDELKKSGFYDKTWQAFTVLLNVRSVGVMGDNRTYDNTVCVRVVEAIDGMTATFAHLPHELLERMSTRIINEVDGINRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL7A_CAEEL
Sequence: MPSKKVIKKKVAAVPAHIRAQTQVQKEVKNPLFEKRARNFNIGQDIQPKKDVTRFVKWPKYIRLQRQSAILQKRLKVPPTINQFRTALDSQSARQAFKLLDKYRPESTEAKKNRLRARAEARAAGKKEEVTKRPNTVRHGVNTITRLVETRRAQLVLIAHDVNPLEIVLHLPALCRKYNVPYAIIKGKASLGTVVRRKTTAAVALVDVNPEDKSALNKLVETVNNNFSERHEEIRKHWGGGVMSAKSDAKKLKIERARARDLGKL
What are the official names of this protein?
60S ribosomal protein L7a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: YCF4_CHLVU
Sequence: MTAQELSIRYEVPGARRFGNYIWGSLMCLGGLGFLTIGISSYLDFPILSLVKSSNIQFFPQGLVMCFYGVLGFLLGVYIWLLILWNLGEGFNEFNLETGYVRIFRWGFPGKNRRIDLQYPIQEIQSIRVEIQEGINPKRIIYLKLRGNREIPLTRAGQPLSIQQIETQAAELAKFLQVSLEGI
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MIAA_PARMW
Sequence: MTQPEPLVITLLGPTASGKTALSLEIAERLNLPVINVDSRQLYREMTVGTAKPTAEQRARVPHHLLDLRNPDQPITLQEFQAEAEPCIQRELQSRGMALLVGGSGLYLKALTSGLKPPAVPPQAQLREQLSQLGQAICHPLLQQADPTAGAKIAPADAVRTQRALEVLYATGRPMSSQATATPPPWRVLELGLDPANLRQRIQQRTDQLYSDGLVEETRQLSERYGADLPLLQTIGYGEALQLLEGTMNQAKANRITTQRTRQFAKRQRTWFRRQHQPHWLAPATELDQAMTLIEQHLR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RS11_LISMF
Sequence: MARKTNTRKRRVKKNIESGIAHIRSTFNNTIVMITDTHGNALAWSSAGSLGFKGSRKSTPFAAQMAAESAAKSAQEHGLKTLEVTVKGPGSGREAAIRALQAAGLEVTAIKDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MBNL1_HUMAN
Sequence: MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM
What is the function of this protein?
Mediates pre-mRNA alternative splicing regulation.  Acts either as activator or repressor of splicing on specific pre-mRNA targets.  Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle.  Antagonizes the alternative splicing activity pattern of CELF proteins.  Regulates the TNNT2 exon 5 skipping through competition with U2AF2.  Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA.  Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly.  Binds to the 5'-YGCU(U/G)Y-3'consensus sequence.  Binds to the IR RNA.  Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
What are the official names of this protein?
Muscleblind-like protein 1, Triplet-expansion RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the muscleblind family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasmic granule. Note=Localized with DDX1, TIAL1 and YBX1 in stress granules upon stress (PubMed:18335541). Localized in the cytoplasm of multinucleated myotubes (PubMed:18335541). Colocalizes with nuclear foci of retained expanded-repeat transcripts in myotubes from patients affected by myotonic dystrophy (PubMed:10970838, PubMed:11590133, PubMed:11929853).
Protein: PPAC_LACDA
Sequence: MEKELIFGHRNPDTDAIGTAIAYSYFQNQHGYNTEAVALGEANDETSFALKKFGFEAPRVVKTVANEVKAIMLVDHNEPQQSVEDRDQVKVTHVIDHHRISNFATIDPLFYRAEPVGCTSTVLWEMFKEQNMEIPANIAGIMLSAIISDTLLLKSPTTTDIDKEAVEELAKIAGVDYKEYGLELLKAGTNIAAKSVEELIDLDAKSFELGSKTARIAQVNVVDVPEALERKDAFLAAMEKDAKANGYDLFMLVITNVLDSDSEVLFIGDDESKSVFAKAFGKELVDSEAHLPGVVSRKKQIVPPLTRAFEA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAC8_CRYNJ
Sequence: MGSALSSCCSPRRKNAYEPLLLETEREAVADLLQYLENRSTTNFFAGSPLAALTTLSFSENVDLQRSAALAFAEITEKEVREVGRDTLDPVLYLLSSHDPEVQRAASAALGNLAVNAENKLLVVSLGGLEPLIRQMLSPNVEVQCNAVGCITNLATHDENKTQIAKSGALVPLTRLAKSKDMRVQRNATGALLNMTHSDENRQQLVAAGAIPVLVSLLNSPDTDVQYYCTTALSNIAVDAANRKKLAQSEPKLVQSLVQLMDSQSLKVQCQAALALRNLASDSKYQLEIVKFGGLKPLLRLLHSSYLPLILSAAACVRNVSIHPANESPIIESGFLQPLIELLSFDENEEVQCHAISTLRNLAASSEKNKGAIVEAGAVEKIKSLVLTVPLAVQSEMTACVAVLALSDDLKPQLLEMGICEVLIPLTNSPSVEVQGNSAAALGNLSSKAAEDYAPFNAVWNKPDGGLHAYLVRFLSSADITFQHIAVWTIVQLLEAEDEQLTNNIRSSPILISSIRQLAKSPPPSRAGGAPRHDPNDPSAGSSEDEFEDGLTDQEGEGEIVSLARRILDLTEVGEEGDEFGERAGRNVPVGSHGQAPGQGQTSQVGSMGSEHAALRASVHRALSGGGRDR
What is the function of this protein?
Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
What are the official names of this protein?
Vacuolar protein 8.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Vacuole membrane; Lipid-anchor.
Protein: TPS9_SELML
Sequence: MWELVETVRSMLNSLHDGEISVSAYDTAWVARVPALDGSNTPQFPMCLNWIMNNQLEDGSWGDRDLFLTYDRICSALACAIALKTWNTGDKIVHKALEFIRKTMPKMELEDSTHMPIGFEIVFPAMIEEAMALELDIDYTAPVLQTIYAERKKKLERIPMNVVQNYPTTLLHSLEGLHKTIDWDKVIKLQSPDGSLLFSPASTACALMHTGNEKCLQYLNNLVKRFNCAVPNVYPVDLFEHLWIVDRLQRLGISRYFTQEIKSALDYVYRYWTDKGIAWARGSPVQDADDTSMAFRLLRSHGYDISPDAFKTFQEGDSFVCFSGQAGQAVTGMYNLYRASQVMFPGETILEEAGSFARKFLEGKRQENQLYDKWIISKDLPGEVEFALDNPMHARLERLATRRYIDQYAADDVWIGKSLYRMPFVNNPIFLELAKADFNMCRALHRKEFQQLERWYDESSLSMFKGFSRSKLEQTFYSAAATIFEPELSPARLIWSQCWFLSLGINEYFDYQGSTKELEDLINNVERWNVNSLGNCSAKVKILFVELYNIVQNHSKQGFLYQGRSIGGALREIWKTWLSSLLQRTKWKMSDNYPTLEEYLKASHSSIEPAVRSTVYFVGETLATGDLKDSAICQMMNTASRLVQDTHTDKVDSSLNSITIYLEENPQLTESEALSQVQALANKNMQKLLYETLQPGALPQACKQLFLNAARIMNVFPGTNKVQAKLSNHVKRVLSQPVL
What is the function of this protein?
Monofunctional diterpene synthase converting geranylgeranyl diphosphate to copalyl diphosphate.
What are the official names of this protein?
Copalyl diphosphate synthase 1, Terpene synthase 9, SmTPS9.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: PHS_SULAC
Sequence: MKLDENEIKRRLGEIEGWSYENNKLKKTFKFKNFYESVEFVRKIQPIADEMDHHPDLCVYYNRVVLELSTHSEGGVTEKDFELAKKINKIQ
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: INO80_NEUCR
Sequence: MDHFSTVLQRPPHFDEDGTEGRGDRGNGAGPGPAPPPPPPRGGLRDILNPVSSNSAVQSQAAAAAPPPPPAVASSSLHGIAASVPPPSSTNSMRATPHSSSSFNLRSPTREPSEYRHPLSSLATPAPFAASPPTSIANANNTNNNNALGAAGSLSSQPPPPPPTGPRSILNPPTPSQQHQQQHHHPNPFVAASAPSLPPPPSSLQAPPAITPIAGLSAPAPASGSLPLSAGGIGNSITVSSSSQPPARASQLHAPSAYYSPAESFRDRDSSVREKSSTGGSFYDPTAEASNGISGSSPRKDRDRDRDHRGTTRESQRRSVSGHSDTGSSWRNATQTSASNKTRDPYNYSPSSADYYNTRKKENYPVDNTTSSSIAAPSNFTVATRSPVAALSHPASIAAPASVGSLTGSISPRLSLRPPSMASPTIRSAVLANPTNGTTSTALPALGRNDSPPSKMSPGTSTNPSRAAGVMSFSNILSSSEPVPRPRATSPNNPDDDDDVPMKVERADSSEKVVKEKKERKPRQPKQPRISDIRHSESTPKGRRGSTKQESPLPNIRIPAKRMANGAPKQQKTFSAENEEKIRKAMDRIETRELPHEDEFEEELRLWRERREYKRQQMNQRDLRQRRQRRADYTEVEAQKLKLHADFGKRRYDDLNYDDALQEVRERELFAEKERKKDMQRKRRREKSMATTMEAKAAALARASAAQDEAERQKYMREAERANKKVQQTRLILQKGIKGPSRNTGPIEPNLEGGTMATFQAENMEPGKTKGKGRAGARPKKSKEQKQAEKDAAEAAQAALDAGLELPPKEETNKIRIKLTKTKAPKEADVDKDKENKEPQEPKEPKEPKEKVIKEKVVEEPKDPLELKFQSKGFNQIYDQIWRDLARKDVNKVFRLAIDSYSTKSSNLKKTAILASKEAKRWQLRTNKGTKDLQARAKRVMRDMMGFWKRNEREERDLRKAAEKQELENARKEEADREAARQKRKLNFLISQTELYSHFIGKKIKTNEVERSTDHPDEIAAEKDKIPENEMDIEVPTGPIGAKVTNFENLDFDAEDESTLRAAAMANAQNAIAEAQKKAREFNKEESKLDEDGEMNFQNPTMMGDVEIEQPKLLNCQLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAEKYDIWGPFLVVAPASTLHNWQQEITKFVPQFKVLPYWGTAGDRKVLRKFWDRKHTTYKKDAPFHVMITSYQLVVSDVAYFQKMKWQYMILDEAQAIKSSQSSRWKCLLGFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLKRLHMILKPFMLRRVKKHVQKELGDKIEMDVFCDLTYRQRAMYANLRNQISIMDLIEKATLGDDDSASLMNLVMQFRKVCNHPDLFERADTASPYSFGHFAETASFIREGSQVTVGYSTRSLIQYELPRLLWRDGGRLHKAGEDNQVAGWRNQWLNEKFNIWTPEHIRESLAGTDNFSWLRFADTSYEEAYRASHKDLFARAVEMSTKKNRLAEIKIAYDEPEDLNFTPAHALFHIREREDRRPLAEITEQGILGSLMNVSRSAFSETGLGRLEQAAAPKASAPPIEVVCDSRSAVVERENIMFNAPMRKVLFGPTLAEEKALVVQKVPPSRYPPPALLPAPDKEKQKFTNITVPSMRRFVTDSGKLAKLDELLRELKENGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQTRPEIFIFLLSTRAGGLGINLTSADTVIFYDSDWNPTIDSQAMDRAHRLGQTKQVTVYRLITRGTIEERIRKRAMQKEEVQRVVITGGSSAAGGGVDFSGRRAPENRNRDIAMWLADDEQAEMIEKRERELLESGELDKMQKKSRGGNKRKRGGAGGEGKEVSLDEMYHEGEGNFDDGGNNIKGSGTATPNGAAGGEGGDGKGAVGGAAKKRKTGGSKKAKTTKQRLAIADGEIDI
What is the function of this protein?
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
What are the official names of this protein?
Chromatin-remodeling ATPase INO80, Chromatin remodeling factor 2-1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATB_WOLPP
Sequence: MTKENWETVIGLEVHAQVSSKTKLFSSSLTEFGTEHNTQVSLVDAAMPGTLPILNYFCIEQAICTGLAISAEINKCSYFDRKNYFYPDLPQGYQITQFFEPIVKNGKVFINNNEKEIRIARIHLEQDAGKSIHEESKTYVDLNRAGVALMEIVSEPDLRSSAEAAEFMKKLRQILRYIGSCDGDMEKGSLRCDANVSVRPNGSSAFGTRCEIKNLNSIRYIVQAIDYEAQRQIKILESGGEISQDTLLFDVTLGKTKVMRSKEDSSDYRYFPEPDLLPVEISQDKIDSIKSSLPELPDQKKLRYINELGINEYDADVITSDKATADYFEELIKKHDSKIAVTWLTVELFGRLNKANIDIVSSPIKADALSELLDFIVDGTISAKLGKQVFDIMFETGKPASLIIEEQDLKQITDRDQISEIIDTIVNNNQDKVQEYKSGKTKLYGFFVGEVMKSTKGKASPDVVNLVLSERLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: KAD6_THEGJ
Sequence: MIIAVTGTPGVGKTTVSKLLAEKLGYEYVSLRDYAIEKGIGEMKGDELEVEVDELTYNFERDFKGKNVVVDGHLSHFLNADLVVVLRAHPRLIGERLTERGYSREKVGENVEAELVDVILVEALEENENVIEVDTTGKTPEEVVNEILELIEKGVKKRVGVVDWSEVYDEVIPYLRL
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
What are the official names of this protein?
Putative adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
Protein: REV_HV1S3
Sequence: MAGRSGGSDRELLTAVRIIKILYQSNPHPSPEGTRQARRNRRRRWRERQRQIHSISERILSTVLGRSSEPVPLQLPPLDRLTLDCSEDCGTSGTQGVGSPQILVESPAVLESGTKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: RNC_XYLFM
Sequence: MISSKASDYQQRIGYVFTDPSLLLQALRHCSAGTPHNERLEFLGDSVVNLLIAEALFQRWPRADEGALTRARSELVRETSLASIARTMQLGEQLILGPGELKSGGHRRDSILADAVEAVIAAIYLDADLATCRTVVLPWFETALTALPVGKPEKDPKTRLQEWLQARQWSLPVYELIFESGDPHTKHFRVSCTLGELKLRTEGEGSSRRLAEQDAASHAINQLDSNK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y444_METMA
Sequence: MTKEVLIHQIIDVLARAGFALSDRCNIRPRSFDVAARKDDTLLLCKVLFNIDGLNEETAREMKYLAEYLGGSAIVVGAKTRDQMLEDSVVYMRYDILALSVQTLYDYFVENIRPLVSAAPGGLYVSIEGDLLKKARTTQSMSLGTLASMVGVSRRTISKYEEEGMDASIDVVLHLEDIFGVELAKPIDILKSCGSRKPRKKAEPEKEEPKGKPGTLLPEDLILNTISMLGYDVLPTAQAPFKAISRDKSSVILTGVSEFNTTVIKRAHLMSSISCITETQSVFIINGRSKLKSVENTVLIEKKELDTISDSQELLDFIEERKDTHEA
What are the official names of this protein?
Putative HTH-type transcriptional regulatory protein MM_0444.
Protein: JZT60_CHIGU
Sequence: MKVAIAICRNIWYSEALSEMNTQILVSILGLAILAALSSGAKAAEPELAVEVSELLKAMEHAPQPQERECRWFWGACKSDSDCCRYLGCKRKWPNICLWSPWG
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U28-theraphotoxin-Cg1a, U28-TRTX-Cg1a, Jingzhaotoxin-60, JZTX-60.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 45 (Jztx-60) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CP81_BP186
Sequence: MSITNATISQRAKKWLEDDRIFIDTETTGLGDDAEIVEICLIDSAGFIMLNTLVKPTKPIPAEATAIHGITDEMVMYAPTWKDIHGAVASLFFEYGFVIYNADYDTRLIYQTAKLYGLENDGFCYFLNERSACAMMLYAEYRGEPGRFKGYKWHKLVDAAAHEGVSVEGKAHRALADCRMTLGIIDALAKGGAA
What are the official names of this protein?
Uncharacterized exonuclease CP81.