PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_TETNG
Sequence: MTLSFFDQFLSPTLFGIPLIALALLLPWTLFPAPSSRWVNSRLLTLQSWFINRFTQQLLLPLNMGGHKWGPYILLVMVFLISINMLGLLPYTFTPTTQLSVNMALAVPVWLMTVIIGLRKNPTAALGHLLPEGTPVPLIPALILIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILTTILLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL22_PSECP
Sequence: MEAKAIARHIRVTPMKARRVVNLVRGLQANEALAILKFAPQAASEPVFKVVQSAISNARVLADRDGVAFDEGDLIISEAFVDEGPTMKRFQPRAQGRAFQIKKRTSHITVVVATPEKEEAR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: HTPX1_SULAC
Sequence: MNVGRKLKTLMFLSGTLTIIAEGIITYLIVSIIGIPTIFTAIFLVILWLIQWLIAPYLVGRNTEEVGPGDPLYEIVRKIAMESKVPTPRVFISYEEYPNAFAFGNYITGKRVAVTKPLLDILNQDELEAVLAHEVGHIKHLDVEIGMALGLIPTIIGYVGNFLLFTGWTLLFFAGDEVELILGLAMLAIGGVLFVLTFLLQIFVLWFNRLRESFADFHSATLYKDKAPYLATALAKIQIYAQNIRTDPFTGIIITAPPIKLKENERDAEELVMKWLHEHISPFADILMTHPHPAKRVKMLYSILQGT
What are the official names of this protein?
Protease HtpX homolog 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y321_BRUME
Sequence: MAGHSQFKNIMHRKGRQDAVRSKMFSKLAREITVAAKQGLPDPAMNPRLRLAIQNAKAQSMPKDNIERAIKKAAGNDGENYDEVRYEGRGPGGVSVIVEALTDNRNRTASNVRAAFTKSGGSLGETGSVSFMFDRVGEIVYKPEAGDADKVMEAAIEAGAEDVQSGEDGHVILCAFEDIGEVSKALEAALGEAESIKTIWKPQTNTELDEEKARSVLKLLSVLEDDDDVQNVYTNFEVSDEVMEKLSA
What are the official names of this protein?
Probable transcriptional regulatory protein BMEI0321.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC11_NEOFI
Sequence: MLSFLSSNLSSTRQSLAQVLNFALVLSTAFMLWKGLSVFTASSSPIVVVLSGSMEPAFQRGDLLFLWNRSPRAELGEIVVYNVRGKDIPIVHRVVRTFPQIEGKAKKVKEVTEASSVPPNMLLTKGDNNIADDTELYAKNQDFLHREEDIVGSVRGYMPMVGYVTIMLSEHPWLKTVLLGIMGLMVILQREQ
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit sec11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: ENO_ENDTX
Sequence: MAKIVKIAGREIIDSRGNPTVEVDVRLGDGTLGRAAVPSGASTGSREALELRDGDKKRFGGKGVLKAVSNVNDIIAPKLTGLEITKQQDIDDIMIKLDGTDFKSSLGANAVLGVSLACAKAGSNSNKLPVYEYVREIYNVKSDKYVLPVPLMNIINGGEHADNNVDLQEFMIAPVSAPTFREALRMGCEVFHGLKKVLNEKGYATGVGDEGGFAPNLKSNAQALEVICEAVKVAGYEVGRDIVFALDVAASELYENNKYTLEGEVKEKVKTSKDMIAFYGDLLKEYPIISIEDGLSESDWDGWKILTEKLKSRLQLVGDDLFVTNTKIFKDGIDKGIANSILIKVNQIGSLSETVAAVQMAYKAGYTAVMSHRSGETEDSIIADLAVALNTGQIKTGSASRTDRMCKYNQLLRIEEELGSKSAYLGKSAFSSIK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL30_BACHK
Sequence: MAKKLEITLTRSVIGRPQDQRATVEALGLKKLNSTVVKEETPAILGMINKVSHLVTVKEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: NUDC_SALEP
Sequence: MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYD
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: 6PGD2_YEAST
Sequence: MSKAVGDLGLVGLAVMGQNLILNAADHGFTVVAYNRTQSKVDRFLANEAKGKSIIGATSIEDLVAKLKKPRKIMLLIKAGAPVDTLIKELVPHLDKGDIIIDGGNSHFPDTNRRYEELTKQGILFVGSGVSGGEDGARFGPSLMPGGSAEAWPHIKNIFQSIAAKSNGEPCCEWVGPAGSGHYVKMVHNGIEYGDMQLICEAYDIMKRIGRFTDKEISEVFDKWNTGVLDSFLIEITRDILKFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSAIKDERKRASKLLAGPTVPKDAIHDREQFVYDLEQALYASKIISYAQGFMLIREAARSYGWKLNNPAIALMWRGGCIIRSVFLAEITKAYRDDPDLENLLFNEFFASAVTKAQSGWRRTIALAATYGIPTPAFSTALAFYDGYRSERLPANLLQAQRDYFGAHTFRILPECASAHLPVDKDIHINWTGHGGNISSSTYQA
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating 2.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: Y400_BACLD
Sequence: MFTQANLFLILLLAIALIAKNQSLIIAVSVLLLIKLIGLDQKLFPAIQSKGINWGVTVITIAVLVPIATGEIGFKQLGEAMKSYYAWIALGAGILVALIAKNGITLLAEDPHITTALVFGTILAVALFKGVAVGPLIGAGIAYLVMQAVQHFTS
What are the official names of this protein?
UPF0756 membrane protein BLi03063/BL00400.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OL492_MOUSE
Sequence: MAFLEDGNHTAVTEFILLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHVGSVDIGYSSSVTPNMLVNFLVEKHTIAYLGCGIQLSSAAFFGTAECFLLATMAYDRFVAICNPLLYSTKMSTQTCIQLVVGSYTGGILNASFAIISFFSFLFCGPNRINHFYCDFAPLVELSCSDINVSVVITTIFSASVTIITVFVIAISYTYILITILKMRSTEGRHKAFSTCTSYLTAVTLFYGTVTFIYVVPKSNYSTDQNKVASVFYIVVIPMLNPLIYSLRNNDIKGALKRQLGKKTFS
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 492, Olfactory receptor 204-18.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NOSY_PSEAE
Sequence: MPVVWTIARKELADGLRNRWLLAISLLFALLSVGIAWFGAAAAGQVGFTSVPATVASLTSLATFLMPLIALLLAYDAIVGEEEGGTLLLLLTYPLGRGQLLLGKFLGHGLILALATLIGFGSAALAILALVPEVEAAILLGAFGRFMGSSLLLGCVFLALAYALSSRASEKSSAAGQALGLWFFFVLLFDLALLAILVLSQGHLSPRLLPWLLLLNPTDLYRLINLSGFDAAAAGGVVPLASDLPVSASALWLALALWAGAALALAHGLFRRRPI
What is the function of this protein?
Required for the assembly of the copper chromophores of nitrous oxide reductase.  Could be part of the ABC transporter complex NosDFY.
What are the official names of this protein?
Probable ABC transporter permease protein NosY.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EF2_CAEEL
Sequence: MVNFTVDEIRALMDRKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGSKAGETRFTDTRKDEQERCITIKSTAISLFFELEKKDLEFVKGENQFETVEVDGKKEKYNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFMNKMDRALLELQLGAEELFQTFQRIVENINVIIATYGDDDGPMGPIMVDPSIGNVGFGSGLHGWAFTLKQFAEMYAGKFGVQVDKLMKNLWGDRFFDLKTKKWSSTQTDESKRGFCQFVLDPIFMVFDAVMNIKKDKTAALVEKLGIKLANDEKDLEGKPLMKVFMRKWLPAGDTMLQMIAFHLPSPVTAQKYRMEMLYEGPHDDEAAVAIKTCDPNGPLMMYISKMVPTSDKGRFYAFGRVFSGKVATGMKARIQGPNYVPGKKEDLYEKTIQRTILMMGRFIEPIEDIPSGNIAGLVGVDQYLVKGGTITTYKDAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIFEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETVQSESNQICLSKSPNKHNRLHCTAQPMPDGLADDIEGGTVNARDEFKARAKILAEKYEYDVTEARKIWCFGPDGTGPNLLMDVTKGVQYLNEIKDSVVAGFQWATREGVLSDENMRGVRFNVHDVTLHADAIHRGGGQIIPTARRVFYASVLTAEPRLLEPVYLVEIQCPEAAVGGIYGVLNRRRGHVFEESQVTGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQVLPGDPLEAGTKPNQIVLDTRKRKGLKEGVPALDNYLDKM
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.  Involved in the morphogenesis of epidermal tissues.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DJC16_HUMAN
Sequence: MEVRKLSISWQFLIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRSNYDQYGDAGENQGYQKQQQQREYRFRHFHENFYFDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVIQELEELGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHNAVVRENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQTPIVPLLYKLTAFAYKDYLSFGYVYVGLRGTEEMTRRYNINIYAPTLLVFKEHINRPADVIQARGMKKQIIDDFITRNKYLLAARLTSQKLFHELCPVKRSHRQRKYCVVLLTAETTKLSKPFEAFLSFALANTQDTVRFVHVYSNRQQEFADTLLPDSEAFQGKSAVSILERRNTAGRVVYKTLEDPWIGSESDKFILLGYLDQLRKDPALLSSEAVLPDLTDELAPVFLLRWFYSASDYISDCWDSIFHNNWREMMPLLSLIFSALFILFGTVIVQAFSDSNDERESSPPEKEEAQEKTGKTEPSFTKENSSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSCLHFSFLSLDKHREWLEYLLEFAQDAAPIPNQYDKHFMERDYTGYVLALNGHKKYFCLFKPQKTVEEEEAIGSCSDVDSSLYLGESRGKPSCGLGSRPIKGKLSKLSLWMERLLEGSLQRFYIPSWPELD
What is the function of this protein?
Plays an important role in regulating the size of autophagosomes during the formation process.
What are the official names of this protein?
DnaJ homolog subfamily C member 16, Endoplasmic reticulum DNA J domain-containing protein 8, ER-resident protein ERdj8, ERdj8.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: DYS3_LIMTE
Sequence: GLVPNLLNNLGL
What are the official names of this protein?
Dynastin-3.
What are the subcellular locations of this protein?
Secreted.
Protein: AIS_ECO57
Sequence: MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLGRLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNHCLTYIAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: XRN2_MOUSE
Sequence: MGVPAFFRWLSRKYPSIIVNCVEEKPKECNGVKIPVDASKPNPNDVEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFEYIDRLFNIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEGMEAAVEKQRVREEILAKGGFLPPEEIKERFDSNCITPGTEFMDNLAKCLRYYIADRLNNDPGWKNLTVILSDASAPGEGEHKIMDYIRRQRAQPNHDPNTHHCLCGADADLIMLGLATHEPNFTIIREEFKPNKPKPCALCNQFGHEVKDCEGLPREKKGKHDELADSLPCAEGEFIFLRLNVLREYLERELTMASLPFPFDVERSIDDWVFMCFFVGNDFLPHLPSLEIREGAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKRKDDEDSFRRRQKEKRKRMKRDQPAFTPSGILTPHALGSRNSPGCQVASNPRQAAYEMRMQRNSSPSISPNTSFASDGSPSPLGGIKRKAEDSDSEPEPEDNVRLWEAGWKQRYYKNKFDVDAADEKFRRKVVQSYVEGLCWVLRYYYQGCASWKWYYPFHYAPFASDFEGIADMSSEFEKGTKPFKPLEQLMGVFPAASGNFLPPTWRKLMSDPDSSIIDFYPEDFAIDLNGKKYAWQGVALLPFVDERRLRAALEEVYPDLTPEENRRNSLGGDVLFVGKLHPLRDFILELYQTGSTEPVDVPPELCHGIQGTFSLDEEAILPDQTVCSPVPMLRDLTQNTAVSINFKDPQFAEDYVFKAAMLPGARKPATVLKPGDWEKSSNGRQWKPQLGFNRDRRPVHLDQAAFRTLGHVTPRGSGTSVYTNTALPPANYQGNNYRPLLRGQAQIPKLMSNMRPQDSWRGPPPLFQQHRFERSVGAEPLLPWNRMIQNQNAAFQPNQYQMLGGPGGYPPRRDDHRGGRQGYPREGRKYPLPPPSGRYSWN
What is the function of this protein?
Possesses 5'->3' exoribonuclease activity.  May promote the termination of transcription by RNA polymerase II.  During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase.  The processive degradation of this 3' fragment by this protein may promote termination of transcription.  Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (By similarity).
What are the official names of this protein?
5'-3' exoribonuclease 2, Protein Dhm1.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MTAD_BACC3
Sequence: MKTTYVNATIVTMNEQNEVIENGYIIVENDKIIDVNSGEFASDFEVDEVIDMKGKWVLPGLVNTHTHVVMSLLRGIGDDMLLQPWLETRIWPLESQFTSQIAVASTELGLLEMVKSGTTSFSDMFNPIGVDQDAIMETVSRSGMRAAVSRTLFSFGTKEDEKKAIEEAEKYVKRYYNESGMLTTMVAPHSPYTCSTELLEECARIAVENQTMVHIHLSETEREVRDIEAQYGKRPVEYAASCGLFKRSTVIAHGVVLNDNERAFLAEHDVRVAHNPNSNLKLGSGIANVKAMLEAGIKVGIATDSVASNNNLDMFEEMRIATLLQKGIHQDATALPVETALTLATKGAAEVIGMKQTGSLEVGKCADFITIDPSNKPHLQPADEVLSHLVYAASGKDISDVIINGKRVVWNGECKTLDEERIIFEASRYKRGLQR
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: NNRE_FUSV7
Sequence: MAIKTLGAKAAAALDQELMSTGAFSIDQLMELAGLAVSQAVYRLQPLESGRRILVACGPGNNGGDGLVAARHLRHYGYNPTVFYPKRSKNDLYQRLAKQLEDLDVPFVDDFSSAVSSTDHIVDAIFGFSFSGEVREPFPAVIQALQETKLPVTSVDAPSSWDIENGPPESGLGSSFMPTALVSLTAPKPLVNHFRGRHFIGGRFVTPAIASKYGFEVPEYKGIDQVVEVETTGQKL
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: R3GEF_MOUSE
Sequence: MWSGQPQQDEGLPVGLSAIPVPWKNLGPSKSNRESSGGLVEASTSWEEAQGEEHPAPAPLDVSRLRSSSMEIREKGSEFLKEELYKAQKELKLKDEECERLCKVRAQLEQELEELTASLFEEAHKMVREANMKQATSEKQLKEAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSPTKAGPRKGHSRQKSTSSSLCPVVCPTAGHIPTPDKEGKEVDTTLFAEFQAWRASPTLDKSCPFLERVYREDVGPCLDFTVQELSALVRTAVEDNTLTIEPVASQTLPAVKVPTVECNNTNTCALSGLARTCHHRIRLGDSDSHYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.  May also activate RAB8A and RAB8B (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange factor for Rab-3A, Rab-3A-interacting-like protein 1, Rab3A-interacting-like protein 1, Rabin3-like 1.
What is the protein family that this protein belongs to?
Belongs to the SEC2 family.
Protein: RNFG_PASMU
Sequence: MKTVKISAYYAILLALIALICTALSTGIYLLTKSKIEDEINKQRQALLLEVVPQAYFDNPLSENCQRPNSEKLRAQRIDRLCIATKNNQKTAYAFETVAPDGYAGRIRLLVGITPTGTILGVRVLEHQETPGLGDKIETRISDWILSFSQQQLRSDNLADWAVKKDGGKFDQFAGATITPRAVVNQVKQSALSLLDELNQEN
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Rnf electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PEX17_YEAST
Sequence: MTSINSFPRNIDWPSNIGIKKIEGTNPTVNAIKGLLYNGGSIYAFLYFVIAMFVEPTLQKQYQQRNDFSLFVLLRLRRIIAQLQKRLVMTPVSSLGFNEQNNFVERSTQTSDDNIIREDNSHWAEMIYQLQNMKQELQYFNRSSGQPSESIDDFVFQIKMVTDQVELTDRSRAFSNKSRNIIQGIREIKGWFVNGQVPR
What is the function of this protein?
Component of the peroxisomal translocation machinery with PEX13 and PEX14.  Interacts indirectly with the PTS1 receptor (PAS10/PEX5) and directly binds to PEX14.  Required for import of both PTS1 and PTS2 proteins.
What are the official names of this protein?
Peroxisomal membrane protein PEX17, Peroxin-17.
What are the subcellular locations of this protein?
Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YMN1_YEAST
Sequence: MVLAKQWVLKNLPTPGEPFNFHFHDPACTFELIEKELSSEQLKDGELLLETTYLSNDPAQKFWISSMDKNYAKGVQPGEIIPARGIGKVLASRNKAFSPGDYVSAVTGWTTHAIISQENVQGLRKLDKNKVGKLWWYLSVLGGTSLTAYFIFFTYAQLQEREEDYGKVYLISGAAGAVGTVCIQLALNVFKASKVIAIAGGPEKVAFVESFGDNVVGVDYKDPSFKQKLIEAAGGENTVDYFIDNVGSNVLEAGVLLLKQRAMLIACGAISAYNDPSKFVFKGYSFILTKRLVVKGVLVTDNIDDFPKALDKLGSLVKHGKIDLLKSATLEDGTGDKFKNVPLIWKGLFSGVNKGKLITKVNNEE
What are the official names of this protein?
Uncharacterized membrane protein YML131W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AGUA_MARMS
Sequence: MSSTLYTSPRLDGFRMPAEHEPQEQVWMAWPTREDNWREKGKHAQAEFVAVATAIAQSTKVTFIVDAKHYEQARLALPDQIRVIEIPSDDCWMRDIGATYVVNDQGERRANSWQFNAWGGELDGLYDSWEQDNAVAEKMAAVTGDYVYHAPLILEGGSIHVDGEGTLYTTEECLLHPSRNPHLSKEDIEDLLKVYLNVEKIIWLKDGLYNDETNGHVDNIMHVIRPGVVALTDCEDSNDPQYAISKAAIKVLSQAIDAKGRTLEIIKLPMPGPLFVSEDEAKNLLKSDSMNRQVGERLAASYANFLITNNSIVFPTFGEKTDEQAKEILQKAFPEHKVIGVYARNILLGGGNIHCITQQVPEKCSIKVV
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: GPMA_YERPY
Sequence: MAVTKLVLVRHGESQWNNENRFTGWYDVDLSEKGRSEAKAAGKLLKDEGFTFDFAYTSVLKRAIHTLWNILDELDQAWLPTEKTWKLNERHYGALQGLNKSETAEKYGDEQVKQWRRGFAITPPALEKSDERFPGHDPRYAKLTDAELPTTESLALTIERVIPYWNDVIKPRIASGERVIIAAHGNSLRALVKYLDDLGEDEILELNIPTGVPLVYEFDENFKPIKHYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: LPXD_XANOM
Sequence: MRLTASAIAGQFGLTVLGDGSTEVSGVATLAHAGAGQLSFLSNPRYRPQLADSQAAVVVLRADDAEAAKGTALVAKDPYTAFAKIAALFDVAQVCEPGIHPSAFIDPTAQVSPGAHVGPFVSIGARSRVGDGCVIGTGSLIGADCVVDDGSELLARVTLVTRVRLGKRVRIHPGAVIGADGFGLAMDAGHWIKVPQLGGVVIGDDCEIGANTCIDRGALEDTVLEEDVRVDNLVQIAHNCRIGAHSAIAGCSGIAGSAKIGRYCLLGGHVGVVGHLEICDKVVITGKSVVRNSINEPGEYSSGTPLTDNRTWRKNAARFKQLDVLARRILAVGKEKE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: AEP3_CANGA
Sequence: MNALKRLGTTLAKNGDQIIEGTKELDQISVKYFLGNTRVSNNEKSLVSISSNKSRLNFNQLIKDNAHLIGKGSQYQRKVVKHYLSPLIGHKLRRQDIHNDYNKQLSHTDHIITPTDRKREAFSSMELAVDILPLLIKSTKKPVTKPAKRRLFKPYYTKEVPPIPDFKGDMKLFEDYIALLTHTKFLYKNSSSSNGIIPKILRVLIHPSNLNTIDLRSVQCYNDILYFYSKKYDFATCRELFAQMKVEGCKPNTTTYNILLLNLVKKVHMRKIRSIKNELLFYLRNMQKNGIFCDTVTWNTCYNFLNDEMSRDLYIEKLIDCGVPLTSELVYSVVRNSSKAHISTKTKYILDMFGEDGESFVNLKFVNLLISDLVLDHNVERAWSVLRYFELKQLKFVNQPKFLINSETMNTFLRYFAEQGRIDLCFLTYNYFVKDLVGPNKIRPNVNTFDMLMKSLVKNGYTETLPTVFEVICALSERYGIKIRNDGYWSLKCKAIIKFQYKSSSCEKNKTELLNKLNNFSWGKQLPLFTTKVWKNGNSEVRKICRMLGSIPIPLRKSRKLGDKETVDRSQNRSVSEKKKAYRNRIKYIAIGNAMARRIPYANNWHQSFKDEVTKRGLLASER
What is the function of this protein?
Required for respiration.
What are the official names of this protein?
ATPase expression protein 3.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: YFBV_SALSV
Sequence: MSTPDNRSVNFFSLFRRGQHYAKTWPMEKRLAPVFVENRVIRMTRYAIRFMPPVAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPSILNWFYEVRGKLQEAGQALAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YfbV.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURA_HAEDU
Sequence: MGKSVAILGAQWGDEGKGKIVDLLTDRVKYVVRYQGGHNAGHTLIINGEKTVLRLIPSGILRENVTCLIGNGVVLSPEALMKEMGELEACGINVRERLKISEACPLILPYHVAMDHAREAALGKNKIGTTGRGIGPAYEDKVARRGLRVSDLFDKEAFATKLKDILDLYNFQLVHYYKVEPVDFQKTLDDVFAVADVIKGMVADVTTLLHQARKEGVNILFEGAQGTMLDIDHGTYPFVTSSNTTAGGVATGAGFGPRNLDYVLGIIKAYCTRVGSGPFTTELFNEEGETIARKGNEFGAVTGRPRRCGWFDAVAVRRAVQINSISGFCMTKLDVLDGFETLKICTAYKMPNGEIVEYAPMAAKDWEGVEPIYETMPGWSENTFGVIKYEALPQAALDYIKRIEELVGVPVDILSTGPDRIETMILRDPFVA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.