PharMolix/UniProtQA huggingface dataset:
Protein: ZNRF3_XENTR
Sequence: MKEPRIRGGLPLVWLWVLLAVAPGESLAKETAFVEVVLFESSPNGDYKTHTTELQGRFSRAGATISAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPEMDPKPCLTVLGKAKRAVQRGATAVIFDVSDNPDAVEQLNQGLEDPLKRPVVYMKGMDAIKLMNIVNKQKGARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLIKIKLKQRRSQNSMNRMAVQALEKMETRKFKAKGKVPREGSCGGLDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHKRCVDPWLLQNHTCPHCRHNIIEQKKGGHGPVCVENSSNRGRQQQQQRVILPVHYPGRVQRTGPIAAYPTRTSMGPHGNPITVLTVERPLEPDLYPARTPTFLAGYRPVSLDHASSGHHCDLEHPPYPAPPAGHGFRRAKYSGRGFNNGTCYSQYETMYQHYYFQGLSYPHQQEVGGSQAPRVVENGHNHSFHSGNNMLYQPAPTLMHMAPPSSVGSCYLHSQHQHRSVCSGYLADVPCSDSSSSSSASSAQGHASSSDSMLDCTEASNQGVYGSCSTFRSSLSSDFDPYVYRSRSPARTGGGDAPGCGGEGGTGSGRGRVECRSHQTFPNSPSRDRLSSCSMEMNYSSNSSLERRGAVISSGTVPDASVSISQGGGKDRRGPEKGCTCCFQRQAGDPSSDCTNLYLGPDPHQTSGPSSSGGLYSVTSSILHRTDPGTVLGHPSRPCCLYEENHGSCYNEDYAVSIQYALAEAAAAAAAAAVAGCEAGQPIPIIPEDPGYDGGLECVGHVSWEMEGEEEEEEVLYCQEGPCCALAEETRALCRSTGKEGAGSTTGQDCHPTDRD
What is the function of this protein?
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components (By similarity).  Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification (PubMed:29769720).
What are the official names of this protein?
E3 ubiquitin-protein ligase ZNRF3, RING-type E3 ubiquitin transferase ZNRF3, Zinc/RING finger protein 3.
What is the protein family that this protein belongs to?
Belongs to the ZNRF3 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: UVRC_SHEB9
Sequence: MSNEFNAQSFLRTVSSSAGVYRMYDVKNDVIYVGKAKDLKKRLTSYFRKNLANVKTQALVSHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRGPQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRSRPCLQYQISRCSAPCVGKVSNADYDEQVKLASLFLKGKDQQVISALVDKMELAAERQAYEQAARFRDQIMALRKVAEQQEVSNNKGDMDVIGVHYSSGIACFHLLFIREGKIFGSRSYYPSVPAQTDMDEVLRSFILQFYLNADIQRTIPKEVVISHNFEELHELEAAISEALDKKFSIKTNVRADRASFLRLAVTNATNAVVTRLSHKNTVEQRFVLLEEILELSTPIQRMECFDISHTMGESTVASCVVFNREGPHKGEYRRYNIEGITPGDDYAAMKQAVSRRFDKIEAGGKIPDILFIDGGLGQLRIAQKIVDEKFVHLDKAPQLIGVAKGEGRKPGLETLILGDTETSFSLEGDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELVKVPGISIEMAQTIHDALRG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUSC_NEIMA
Sequence: MIDGQTTEPKQKTRIILAPMQGLVDDVMRDLLTRIGGYDECVSEFVRITHTVHSRATWLKYVPEIANGNKTFSGTPCTVQLLGSDADNMAANALEAVRFGADKIDLNFGCPAPTVNRHKGGAILLKEPELIFHIVKTLRERLPAHIPLTAKMRLGYEDKSPALECACAIAEGGACGLTVHARTKAEGYEPPAHWEWIRKIRDSVDIPVTANGDVFSLQDYIGIKTISGCNSVMLGRGAVIRPDLARQIKQYENGGPVKDTDFAEVSKWIRQFFELCLTKEANNKYPIARLKQWLGMMKKTFDPAQTLFDRVRTVKDADEVRRILNAFEHEINV
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U16 in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(16) synthase, U16-specific dihydrouridine synthase, U16-specific Dus, tRNA-dihydrouridine synthase C.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusC subfamily.
Protein: GUAA_SHEB9
Sequence: MSDIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIILAGGPESVTAENSPRAPEYVFTAGVPVLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIEMLTDSLLFKGIEDAVNSEGKPLLDVWMSHGDKVSAIPEGFVAVAKTDTCPFAAMANEEKQFFGVQFHPEVTHTRQGMRMLSHFALDICGCAANWKPSSIIEDAIERLKKQIGDDEVILGLSGGVDSSVVAMLLHRAIGKKLTCVFVDNGLLRLNEAEQVMEMFGDHFGLNIIHVDAENRFLDAMKGEADPEAKRKIIGRVFVEIFDEESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMELGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: REEP4_XENLA
Sequence: MVSWIISRAVVLVFGLLYPAYASYKAVKTKNVRDYVRWMMYWIVFALFMTVETFTDIFIAWFPFYYEIKMAFVVWLLSPYTRGASLLYRKCIHPTLSLKEKEIDSYIIQAKERSYESFVNIGRKGLNIAASAAVQAATKGQGALVGRLRSFSMQDLRALPDDTPIHYTDALYPDEPQLHRRPMGFPTTSQADSDSMDERWSDSEIAETRTAARTRGGMPSKSLQRSQSLRVSKKKGLSREVSTKTTKPRAKKKPAQSEPEN
What is the function of this protein?
Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis.  Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes (By similarity).  May play a role in the maintenance of both the nervous system and the musculature.
What are the official names of this protein?
Receptor expression-enhancing protein 4.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PGK_BACAA
Sequence: MNKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLVEQGAKVILASHLGRPKGQAVEELRLTPVAARLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFYAGEEKNDAELAKEFAALADIFVNDAFGAAHRAHASTAGIADYLPAVSGLLMEKELEVLGKALSNPERPFTAIIGGAKVKDKIGLIRHLLDKVDNLIIGGGLAYTFVKALGHEIGLSLCEDDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATTKIVGIDSIPSNWEGVDIGPKTREIYADVIKNSKLVVWNGPMGVFEMTPFAEGTKAVGQALADAEGTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLEFMEGKELPGVVCLNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_LYSSC
Sequence: MTLQQQIIEELRVQPTINAQEEIRKSIDFLKEYAKHYSFVKGFVLGISGGQDSTLTGKLAQLAVDELNKEVGEMKYSFWAIRLPYGVQADEQDCQDAIDYIKPTGSYTVNIKDAVDASVKALANAGVELNDFVKGNEKARERMKVQYSIAAMNGGVVLGTDHAAEAITGFYTKFGDGGADLMPIFRLNKRQGKQLLAELNCPEHLYTKVPTADLEENRPSLPDEVALGVSYDQIDDYLEGKEIPEEPRQLLEGYYLRSQHKRHMPITIFDVFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: H2A2_LEIIN
Sequence: MATPRSAKKAARKSGSKSAKCGLIFPVGRVGGMMRRGQYARRIGASGAVYLAAVLEYLTAELLELSVKAAAQSGKKRCRLNPRTVMLAARHDDDIGTLLKNVTLSHSGVVPSVSKAVAKKKGGKKGRATPSA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYH_MYCTO
Sequence: MTEFSSFSAPKGVPDYVPPDSAQFVAVRDGLLAAARQAGYSHIELPIFEDTALFARGVGESTDVVSKEMYTFADRGDRSVTLRPEGTAGVVRAVIEHGLDRGALPVKLCYAGPFFRYERPQAGRYRQLQQVGVEAIGVDDPALDAEVIAIADAGFRSLGLDGFRLEITSLGDESCRPQYRELLQEFLFGLDLDEDTRRRAGINPLRVLDDKRPELRAMTASAPVLLDHLSDVAKQHFDTVLAHLDALGVPYVINPRMVRGLDYYTKTAFEFVHDGLGAQSGIGGGGRYDGLMHQLGGQDLSGIGFGLGVDRTVLALRAEGKTAGDSARCDVFGVPLGEAAKLRLAVLAGRLRAAGVRVDLAYGDRGLKGAMRAAARSGARVALVAGDRDIEAGTVAVKDLTTGEQVSVSMDSVVAEVISRLAG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPC2_EMENI
Sequence: MKLLSPATALLFLAPLAVTATPASFFGYTQDVIAEGAPVRGDNPLEYCSEPSGDILEINSVDLAPNPPKAGTTLKIRAAGNLHERIEAGAYVVLEVKYGLITLLRDTADLCAQLTNVDLQCPLEEGPMVLTKEVDLPSQIPRGRYTVHADVYTKDNKRITCLDAKNIQF
What is the function of this protein?
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
What are the official names of this protein?
Phosphatidylglycerol/phosphatidylinositol transfer protein, PG/PI-TP.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y906_MYCTU
Sequence: MVRRALRLAAGTASLAAGTWLLRALHGTPAALGADAASIRAVSEQSPNYRDGAFVNLDPASMFTLDREELRLIVWELVARHSASRPAAPIPLASPNIYRGDASRLAVSWFGHSTALLEIDGYRVLTDPVWSDRCSPSDVVGPQRLHPPPVQLAALPAVDAVVISHDHYDHLDIDTVVALVGMQRAPFLVPLGVGAHLRSWGVPQDRIVELDWNQSAQVDELTVVCVPARHFSGRFLSRNTTLWASWAFVGPNHRAYFGGDTGYTKSFTQIGADHGPFDLTLLPIGAYNTAWPDIHMNPEEAVRAHLDVTDSGSGMLVPVHWGTFRLAPHPWGEPVERLLAAAEPEHVTVAVPLPGQRVDPTGPMRLHPWWRL
What are the official names of this protein?
Uncharacterized protein Rv0906.
What is the protein family that this protein belongs to?
To K.pneumoniae RomA.
Protein: CH10_FRAP2
Sequence: MNIRPLQDRVLVRRAEEETKSAGGIILTGSAQEKPSQGEVVAVGNGKKLDNGSTQPMDVKVGDKVLFGKYSGSEVKVNDETLLMMREDDIMGIIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y507_ZYMMO
Sequence: MFSFSINTGSKKTLYSDLLTTLKELLSEEGDPIANMANTAALIWTYMPDLNWVGFYRAIRSYLILGPFQGKVACVKIPYGRGVCGTAAATGRIQCVRDVHTYPNHISCDPSAASELVIPIRGRQNQILAVIDLESPTMGRFDAEDVEGCSRLMEVLGRFLG
What are the official names of this protein?
Protein ZMO0507.
What is the protein family that this protein belongs to?
Belongs to the free Met sulfoxide reductase family.
Protein: TOLB_VESOH
Sequence: MKQFIVFILSLYTTLSWAVLEVTIFKQEENTFPIVISDFFVVGDASQGKVIADIMRNNFNRSGEFSVVNANYIIRSKPSFDKWKAKKIEAIVLGKLEKISKKIFNVEIELLDVYSKKTLYKDIFTVHNSGIRRIAHYLSDQIYHALLGKRGFFNTRLAYITVINKDKGEREYRLEISDSDAQNPQTILKSREPLLSPVWSPKQDKIAYVSFKNSRSEVFIQYPFIRRKIQKLPYFDGIASSPSWHPNGEILLLTLSKNGNKDIYSYQLSSKKLTRLTIDMGIDTEASYSPDGNKIIFTSNRSGQVQVYIKDLKTNKINRATFKGRYNAQAVFSPDGKSLIMVHKIDQDYRIALLDIATKDLKVMTNNQLDESPFFSPNGDMIIFATNQGGFGVLSVVSIWGRQIFELTSKVGEVREPNWSHYLK
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: UVRB_LACP3
Sequence: MIERIADRKFDLVSPYQPAGDQPQAIAKLTKGFEEGKKEQILLGATGTGKTFTMSNIIANLNKPTLILSHNKTLAGQLYGEFKEFFPHNAVEYFVSYYDYYQPEAYVPSTDTYIEKDSAINDEIDKLRHSATSALLERNDVIVVASVSSIFGLGDPHEYKNHVLSLRTGMTIDRNTLLRQLVDIQFDRNDIDFQRGRFRVRGDVVEIFPASRDDHAIRVEFFGDEIDRITEVDALTGEVIGTRDHVAIFPATHFMTSDEQMQRAIKSIAAELEAQLKVLRSENKLLEAQRLEQRTNYDIEMMREMGFTSGIENYSRHMDGRKPGEPPYTLLDFFPKDFNIMVDESHVTMPQIRGMYNGDRARKQMLVNYGFRLPSALDNRPLKINEFEQHVHRILYVSATPGPYELDRVPKDDIAEQIIRPTGLLDPKIEVRPVMGQIDDLVGEINKRVDAHERVFITTLTKKMAEDLTDYLKDMGIKVRYLHSDIKTLERTQIIRDLRLGKFDVLIGINLLREGIDVPEVSLIAILDADKEGFLRAERSLIQTIGRASRNEHGKVIMYADKVTDSMKAAIDETQRRRTIQEKFNEEHHITPKTIIKPIRAAISSYEQSDDDKAEAKKTFAEVDYEDMSKADKKELVANLRSQMQAAAKKLDFEQAASLRDTILELQADMS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_PHOLL
Sequence: MSNSYLAFPNIDPVIFSIGPIALHWYGFMYLVGFVFAMWLATRRAAKPNSGWTKNEVENLLYAGFAGVFVGGRLGYVLFYNFPAFLDNPLYLFKVWDGGMSFHGGLVGVICAMWWFGRRTKRHFLQVADFIAPLVPFGLGMGRIGNFINGELWGRVTLDTPWAMLFPSSRGEDIALAATDPSLLSVLEQYGVLPRHPSQLYEMALEGIVLFIILNLYIRKPRPMGSVSGLFLIGYGIFRVIVEFFRQPDAQLGLFDGISMGQILSIPMILAGILMMIWAYKHQGNKVQEVK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: JBP2_TRYCC
Sequence: MPVPSHVSVATLQSVLQTVCSTGEPAIIAPSSFLGELDTVVDEVKRHGMKLASIPHGGITILPPVPISGTELFDFCAEYCKAQTHEERLAVRHKINNHNFLMQDPLLRMPCRQLYNPADYVLRIVHLCSELVSASEEEYHGAYGVAPLLHINPVQDVCGKLRSMFQSGSLYVKPWILEEEEERREMDESNRGVLFNSDSFGNGRGGSSISSSERSVDENDVADEDLTGEEVVDNATDTVVEYLSEKDFDVVTESGIFYDDSGERVHAIYLRGGIKKELCQRAAIAIEEAATTKNLRKAVNGGKTNPETGIVGYYDYLNNPTQRKCRETEFTRKNWSSVVDSCEPFLVALNKLYSECAPTHYKLQRIAIPHHYQLFNTVFSTMTVNRNFRTAVHTDRGDFRSGLAALCVIDGVFEGCHLAIKKLGKAFRLETGDVLFFDTSLEHGNTEVHNFDYCWKRVSVVCYLRNGLMSQICEMERRRWLQKQMLKQRLLDRSRQSVINLNATDPNLPPIYLPGRLLEVLSPVQQAALGFVVDRLSKGNGCVIALTMGLGKTLLSLALCYSHMYDQNPRDVLILAPKIVLTHWTGEKQKWEKYGLVFSHFVVSDGTDSVSFEIALKRYKQQLNGELPRTSHVFVINPEYIRTVLKKLTGFRPSLIIVDEGHRVSSKGSKLKDWLEGLRCTARVILSGTPVQNNAEELYRLIGWINSDVHSVLPPRVFTDLAGTINRYINGDDSALAAAVSAQRYIQEWMCSYVFSVMKTDLPPLNDYIIICGFSSIQRKMLEDHFGMEGIDGLTSIKASEHRPYHLSTHPLCFLGFISGVYKSLNGNHKLTPEAEEELESQEYASQLYSLTEDDIGLIDECLSLVNSGFLTEFVGLSGKMTVLISILHSIREKKEKAIIFSQYVGSQDFISRTLTSFDIVSSTIRGRDCHERRRRTIEKFREDEKITCLLLSTQIGAYGLDFTAANHVILWDSWWNPQVESQAIARAYRRNQTRAVIVYRLASEFEDTIVLKTQIRKLALFRCIMNEEASRAVPPEELLDCVDTEEDEGRRFLWRSLKKSYLEGGAPAVSKVFRHGDTVRSESWS
What is the function of this protein?
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU).  DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation.  Probably also acts as a DNA helicase.  Recognizes and binds specific regions of the genome, hydrolyzes ATP and allows the DNA base J de novo synthesis.  Involved in initial synthesis of DNA base J, JBP1 being able to act via the basal level of DNA base J and propagate further synthesis.  In contrast to JBP1, it does not specifically bind DNA base J, however it binds chromatin (By similarity).
What are the official names of this protein?
Bifunctional helicase and thymine dioxygenase JBP2, J-binding protein 2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the TET family. JBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAND_RIPO1
Sequence: MKRTFLNSKIHRATVTGSELNYVGSMAIDAELMKAANILPFERIEIVNVNNGQRWATYVIEAEPGSGIMEVRGAAARLAEVGDIVIIFTYIEIEEPIPVPWHPRVVMVNEKNQISEIRHIAADKPSELLFSL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM24_YEAST
Sequence: MISPRVNTRVWQRSISLLSPQAAKTESNVVTKERTYIENLSKDIATSRFRLVDENGKIASITVQPDIPICIKKDCLVSIHNLNHLSLSYKWLNFWSNLIKFRSFKSSLFHRIIGSSVLEILAAPNFQTSRRPFDSSRSLSVLNLTGTKDWNVFGKDSIIAFEQNSSLEIKSPIFPSARSLVSNSSKSQLPRKFQILNGRGNVLVCGGGLVYSIELIDESDKILVNSRNILAINGQSQLDIANSVERQELHVEGAYVGDSSNDTVAPKFIKNQTLKSAYGHTVQFFKRMRSWIRNQYEKRYIYGVDSYFMKIKGPRTILIQTHEMTTSKDNILTKLTSKGHVKKSNVNDNGVNLEKQVANDVNSKIIELANRPSLFIATVSQDGRVDFQSTSKFT
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial, Found in mitochondrial proteome protein 26.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NTAQ1_ORYSI
Sequence: MADDRVAGGATPPPPPPPPPLDASAFTHTPYYCEENVHLLCKELIRSGISDPAGTDLYAVFISNEEKKVPLWYQKASHSGDGFVLWDYHVICIQSRRKNGEVLDLVWDLDSSLPFPCSFIQYVSDAIRPLSFGNSTYRRLFRVIHAPVFLRSFASDRSHMKDHAGNWIQLPPKYESIVAEDGTTNNLNEYITMSMDDVKDLESMADDVYSSKHGVVINETILPEFFSRLPG
What is the function of this protein?
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation.  Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule.  Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.
What are the official names of this protein?
Protein N-terminal glutamine amidohydrolase, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase.
What is the protein family that this protein belongs to?
Belongs to the NTAQ1 family.
Protein: CEAM_ECOLX
Sequence: METLTVHAPSPSTNLPSYGNGAFSLSAPHVPGAGPLLVQVVYSFFQSPNMCLQALTQLEDYIKKHGASNPLTLQIISTNIGYFCNADRNLVLHPGISVYDAYHFAKPAPSQYDYRSMNMKQMSGNVTTPIVALAHYLWGNGAERSVNIANIGLKISPMKINQIKDIIKSGVVGTFPVSTKFTHATGDYNVITGAYLGNITLKTEGTLTISANGSWTYNGVVRSYDDKYDFNASTHRGIIGESLTRLGAMFSGKEYQILLPGEIHIKESGKR
What is the function of this protein?
This is a calcium-requiring inhibitor for murein biosynthesis; it causes lysis of sensitive cells accompanied by murein degradation.  The target site is possibly the cytoplasmic membrane.
What are the official names of this protein?
Colicin-M.
Protein: MURB_POLAQ
Sequence: MNRAQNAPQPSKLTRNLGLQGRNTFGFDASAELAYEITSAEQIPEVMESIAAQKLSWRVLGGGSNVILPKVLPGATLLMNITGAEITSSNQEHSLVAVGGGVNWHDFVLWSLDNDLPGLENLALIPGTVGAAPIQNIGAYGIEVADYIDSIEAFDAHTDSFVTLPKSACHFAYRDSYFKQHPHRFIVTKVVFKLPKQWQARIHYADLANQFAANATPCPEEIFLAVCKIRTRKLPDPKVIGNAGSFFQNPIVPNEQHETLLGKHPNLVSYPDAPGKRKLAAGWLIDQCGFKGERMGNVGVYENQALVLVNHGGGTAQDILGLAKCIQEKVRKEFGVSLEIEPNIL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPFC_STRMU
Sequence: MSQQKIGVLLVNLGTPEHPTAPAIRKFLKPFLADSRVIDYPKFLWKPILYSFILPFRPRKVKPLYQHVWTNEGSPLYANAIGQEKALQAHFDQSEHGVLVRATMAYSKPSISDVVDEFLKEKVAKMIVLPLFPQYSSTTTAAIFDAFAQSLKKKKDIPPFDFIHHYYERPSYIQALAQTIHLQENEHLLFSFHGIPQRYVIEGDYYTEHCQQTAQLIAVAAGLSEEQWQVSYQSRFGPEEWTRPYTDETLIQLPKQGKKKLAVICPGFAADCLETLEEIDITNRKHFMAAGGQAYRYIPALNASPAHIQLLAELISERL
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCH3_ARATH
Sequence: MEMMKIDPLFDRASELKAFDETKTGVKGLVDSGVSQVPRIFHHPTVKLSTPKPLPSDLLHLKTIPTIDLGGRDFQDAIKRNNAIEEIKEAAAKWGFFQVINHGVSLELLEKMKKGVRDFHEQSQEVRKEFYSRDFSRRFLYLSNFDLFSSPAANWRDTFSCTMAPDTPKPQDLPEICRDIMMEYSKQVMNLGKFLFELLSEALGLEPNHLNDMDCSKGLLMLSHYYPPCPEPDLTLGTSQHSDNSFLTVLLPDQIEGLQVRREGHWFDVPHVSGALIINIGDLLQLITNDKFISLEHRVLANRATRARVSVACFFTTGVRPNPRMYGPIRELVSEENPPKYRETTIKDYATYFNAKGLDGTSALLHFKI
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase homolog 3.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RL21_THEMA
Sequence: MLYAIVETAGRQYRVEEGKILYTEKQKDYSPGDEIVFDRVVFVRKDGEVLVGKPYVEGAKVVGKVLEHAKARKVKTVKYRPRKNSKVEKGHRQWYTAIKIEKIEL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: AAC6_SALEN
Sequence: MDIRQMNKTHLEHWRGLRKQLWPGHPDDAHLADGEEILQADHLASFIAMADGVAIGFADASIRHDYVNGCDSSPVVFLEGIFVLPSFRQRGVAKQLIAAVQRWGTNKGCREMASDTSPENTISQKVHQALGFEETERVIFYRKRC
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring including amikacin, tobramycin, dibekacin and ribostamycin.  Able to acetylate eukaryotic histone proteins.
What are the official names of this protein?
Aminoglycoside N(6')-acetyltransferase type 1, AAC(6')-Iy, Aminoglycoside resistance protein.
Protein: RL21_CLAMS
Sequence: MVYAVVRAGGRQEKVEVGTIVTMDRVKNQQSGKVVLPAVLLVDGDTITTDAAKLADVTVSAEILNDLRGPKIVIQKFKNKTGYKKRQGHRQDLTRVQVTEIN
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.