PharMolix/UniProtQA huggingface dataset:
Protein: HACD3_DANRE
Sequence: MSALTPHVYWAQRHGEIYLRVEISDAQDLSIGVEENILQFRGQGHGAKGENEYEFSLEFLKPVKPEVKHKSTQRQVNITVRKQEEVWWNRLTKQEKKPLFLAPDFDRWLDESDAEMELREKEEKINKVSFESRVRKDPFLGLKKGFLFMYNLVQFLGYSWIFVNMTVRLFILGQDSFYDTFHTIADVMYFCQMLAIMEVINPAVGLVKTGVMPAFIQVMGRNFILFVIFGSLEDMQNKPVVFFVFYLWSTIEIFRYPFYMLACIDTEWKLLTWLRYTIWMPLYPLGVLAEAVAVIQSIPIFDETKLLSIPLPKATGLSLSFSYILQLYLVVMFLGLFINFRHLFKQRTRRFRTKKRKAN
What is the function of this protein?
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation.  Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  Involved in Rac1-signaling pathways leading to the modulation of gene expression.
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase, 3-hydroxyacyl-CoA dehydratase, HACD, Protein-tyrosine phosphatase-like A domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CRBN_CHICK
Sequence: MAAEEGGDGRRNMGNPPPPAPAESEEEDDNEMEVEDQDGKEAEKPNMINFDTSLPTSHMYLGSDMEEFHGRTLHDDDSCQVIPVLPHVMVMLIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVREREAHFGTTAEIYAYREEQEYGIETVKVKAIGRQRFKVLEIRTQSDGIQQAKVQILPERVLPSTMSAVQLQSLSRRHIFPSSKPKVWQDRAFRQWWQKYQKRKFHCASLTSWPPWLYSLYDAETLMERVKRQLHEWDENLKDESLPTNPIDFSYRVAACLPIDDALRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQDTEITTKNEIFSLSLCGPMAAYVNPHGYIHETLTVYKACNLNLSGRPSTEHSWFPGYAWTIAQCRICGNHMGWKFTATKKDMSPQKFWGLTRSALLPRIPEAEDELGHDRSPLLCL
What is the function of this protein?
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2 (Probable).  Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8 (PubMed:20223979).  Maintains presynaptic glutamate release and consequently cognitive functions, such as memory and learning, by negatively regulating large-conductance calcium-activated potassium (BK) channels in excitatory neurons.  Likely to function by regulating the assembly and neuronal surface expression of BK channels via its interaction with KCNT1 (By similarity).  May also be involved in regulating anxiety-like behaviors via a BK channel-independent mechanism (By similarity).
What are the official names of this protein?
Protein cereblon.
What is the protein family that this protein belongs to?
Belongs to the CRBN family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PRAF1_MOUSE
Sequence: MAAQKDQQKDAEGEGLSATTLLPKLIPSGAGREWLERRRATIRPWGTFVDQQRFSRPRNVGELCQRLVRNVEYYQSNYVFVFLGLILYCVVTSPMLLVALAVFFGACYILYLRTLQSKLVLFGREVSPAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVLIGSHAAFHQMEPADGEELQMEPV
What is the function of this protein?
General Rab protein regulator required for vesicle formation from the Golgi complex.  May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes.  In addition it inhibits the removal of Rab GTPases from the membrane by GDI1 (By similarity).
What are the official names of this protein?
Prenylated Rab acceptor protein 1, PRA1 family protein 1, Prenylin.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=According to PubMed:11535589, it is an integral membrane protein, while other authors showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles.
Protein: VE8E2_BPV3
Sequence: MKIFLQSSLPPGPNRRRGPQTRGHPRHKSASFRRSASSGSDTRDSRGRSRSPSSSRSRSRSRSRSPSGSHSRPRAPHVPDQETGRPPGGGGRRGSRDQQQGPGGPAPPSPGEVGTRSGPPETKAKGRLAELISAAYDPPVLLLQGCANTLKSFRRRTTQSYPHTFLCMSTSWTWASKTCTVKSGHRMLVAFVNSEQRTLFLATVKIPKGVTCLKGSFDGL
What is the function of this protein?
Plays a role in limiting the replication of viral DNA in keratinocytes.  Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.
What are the official names of this protein?
Protein E8^E2C.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E8^E2C protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: NADC_SYNY3
Sequence: MMRILVTNPAPMTCLPPWIIIDPWLQQWLAEDIGRGDWSTQGLGLQHRGQARWVAKENGVIAGLPMAARIFQLLDPSMEFQVLAGEGQAVTASTVVATMAGNLGSLLTGERVALNLVMGLSGIATMTRQYVQAIADYPTRFVDTRKTTPGLRVLEKYASRLGGAMNHRLGLDDAVMVKDNHIQAAGSITKAVQTLRQNLPYPLAIEVETSNLEEVQEAIATQVEIIMLDNMGTDTMATAVKLIRQANPLIRIEASGNVTLANLTAIASTGVDFISSSAPITRSPWLDLSMQIVRN
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Probable nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: CBPA_PSEPW
Sequence: MDFKDYYKILGVEPTADEKAIKAAYRKLARKYHPDVSKERDAEEKFKEANEAYEVLGDAQKRAEFDEIRKYGGQHGRPFQAPPGWENRGGAGGGFEGGDFSDFFSSIFGARGGNPFGGARQQRSAGRRGQDVELELAIFLEETLSKESKQISFQVPQTNAAGQRTGFTTKTLNVKIPAGVSDGERIRLKGQGAPGSAGGANGDLFLTIRMAPHPLFDVEGQDLIITVPLAPWEAALGTKVAVPTLDGKINLTIRPDSQSGQRLRVPGKGLANKQGERGNLYAQLKVVMPPASDASTRQLWTQLSEKAAFNPRTQWSK
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ATPA_NOCSJ
Sequence: MTELSIRPDEIRDALQRFVSEYQPDAASKEEVGTVAQAGDGIARVSGLPSAMANELLEFEDGTMGLALNLDTREIGVVILGDFEGIEEGQTVRRTGEILSVPVGDNFMGRVVDPLGKPIDGLGEIEAETRRALELQAPTVMQRKSVHEPLATGIKAIDSMTPIGRGQRQLIIGDRATGKTTIAIDTIINQKQNWESGDPAKQVRCIYVAIGQKGSTIASVRGALEEAGALEYTTIVASPASDSAGFKYLAPYTGSAIGQHWMYDGKHVLIIFDDLTKQAEAYRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDMGAGSMTGLPIIETKANDVSAYIPTNVISITDGQIFLQSDLFASNQRPAIDVGVSVSRVGGSAMTKAMKAVTGSLKVDLAQFRAMEAFAMFASDLDAASRQQLDRGQRLMALLKQPAYSPYPVEEMTVSLWLGTSGRLDKVPTEDVLRFEREFLDFLRRSHEGILSAIRETLKFEDDTESSLEDAYNSFLDQFQTSEGGSIKVGHEPEAEALADEDVEQEQIVRQKRG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYW_THEAC
Sequence: MINPWSSSDFFDYERLKREFGIGDMNVPFDHFLFRRHLILGQRSIDYIDYALKHHMKFNVMTGLMPSGEMHLGNKSAIDQVIFFQKLGGRVSIAVADLESYSTRGISLERAREVAIEKYILNYIAMGLEPCEIYFQSRNSDVQFLAYMLGNRTNMSELRSLYGFTDTHDLLHINAPLIQAADVLHTQMKKYGGPAPTVVPVGFDQDPHLRLMRDLAKRMRIFNIQLENDLVVSVRGKDDPKEYIDMAYEYLSSRYTNVKKDYEYRVVRADGVDQQDLVGIDLDLAHMETKYNDFAFIAPSATYQKLMKGLKGGKMSSSVPDSLISLNDDPKEARRKIMAGMTGGRDTEEEQRRLGGEPDRCPIFDLYNYEIDDDKHVKEVYDDCRNGKRMCGFCKREIADRMASWLSDLSKKREEAREKLSLYIHE
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKA12_MOUSE
Sequence: MGAGSSTEQRSPEQPAESDTPSELELSGHGPAAEASGAAGDPADADPATKLPQKNGQLSAVNGVAEQEDVHVQEESQDGQEEEVTVEDVGQRESEDVKEKDRAKEMAASSTVVEDITKDEQEETPEIIEQIPASESNVEEMAQAAESQANDVGFKKVFKFVGFKFTVKKDKNEKSDTVQLLTVKKDEGEGAEASVGAGDHQEPGVETVGESASKESELKQSTEKQEGTLKQAQSSTEIPLQAESGQGTEEEAAKDGEENREKEPTKPLESPTSPVSNETTSSFKKFFTHGWAGWRKKTSFKKPKEDDLETSEKRKEQEAEKVDEEEGEKTEPAPAEEQEPAEGTDQARLSADYEKVELPLEDQVGDLEALSEKCAPLATEVFDEKTEAHQEVVAEVHVSTVEKMTKGQGGAEVEGDVVVEGSGESLPPEKLAETQEVPQEAEPVEELMKTKEVCVSGGDHTQLTDLSPEEKMLPKHPEGIVSEVEMLSSQERIKVQGSPLKKLFSSSGLKKLSGKKQKGKRGGGGGDEEPGEYQHIQTESPESADEQKGESSASSPEEPEEIACLEKGPSEAPQEAEAEEGATSDGEKKREGITPWASFKKMVTPKKRVRRPSESDKEEELDKVKSATLSSTESTASGMQDEVRAVGEEQRSEEPKRRVDTSVSWEALICVGSSKKRARKASSSDDEGGPRTLGGDGHRAEEASKDKEADALPASTQEQDQAHGSSSPEPAGSPSEGEGVSTWESFKRLVTPRKKSKSKLEERAEDSGAEQLASEIEPSREESWVSIKKFIPGRRKKRADGKQEQAAVEDSGPGEINEDDPDVPAVVPLSEYDAVEREKLEAQRAQENVELPQLKGAVYVSEELSKTLVHTVSVAVIDGTRAVTSAEERSPSWISASMTEPLEHAEGVATPPVGEVTEKDITAEATPALAQTLPGGKDAHDDIVTSEVDFTSEAVTAAETTEALRAEELTEASGAEETTDMVSAVSQLSDSPDTTEEATPVQEVEGGMLDTEEQERQTQAVLQAVADKVKEDSQVPATQTLQRAGPKALEKVEEVEEDSEVLATEKEKDVVPEGPVQEAETEHLAQGSETVQATPESLEVPEVTEDVDRATTCQVIKHQQLMEQAVAPESSETLTDSETNGSTPLADSDTPNGTQQDETVDSQDSNAIAAVKQSQVTEEEAAAAQTEGPSTPSSFPAQEEHREKPGRDVLEPTQALAAGAVPILAKAEVGQEGEAGQFDGEKVKDGQCVKELEVPVHTGPNSQKTADLTRDSEVMEVARCQETESNEEQSISPEKREMGTDVEKEETETKTEQASEEHEQETAAPEHEGTHPKPVLTADMPHSERGKALGSLEGSPSLPDQDKADCIEVQVQSSDTPVTQTTEAVKKVEETVATSEMDESLECAGAQSLPAEKLSETGGYGTLQHGEDTVPQGPESQAESIPIIVTPAPESILHSDLQREVSASQKQRSDEDNKPDAGPDAAGKESAAREKILRAEPEILELESKSNKIVQSVIQTAVDQFARTETAPETHASDLQNQVPVMQADSQGAQQMLDKDESDLQVSPQDGTLSAVAQEGLAVSDSSEGMSKASEMITTLAVESASVKESVEKLPLQCKDEKEHAADGPQHQSLAKAEADASGNLTKESPDTNGPKLTEEGDALKEEMNKAQTEEDDLQEPKGDLTES
What is the function of this protein?
Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
What are the official names of this protein?
A-kinase anchor protein 12, AKAP-12, Germ cell lineage protein gercelin, Src-suppressed C kinase substrate, SSeCKS.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Membrane; Lipid-anchor.
Protein: RSMH_STRZP
Sequence: MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSKLSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGICYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYGEDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPDDLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_BRUAB
Sequence: MAETSSLISGVAQRYAGSLFEHALDANSVASVEKDLGRFEALLSGSEDLRRLISSPVFSSEDQLHAIGAIADKAGIKGLVGNFLRVVAQNRRLFALPGIIAAFRQIAAEHRGEISADVVSAHELTSAQQNELKATLKGVAGKDVTINVTVDPSILGGLIVKMGSRQIDTSLRTKLSSLKLALKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS9_DEHM1
Sequence: MVEKNTYFIGVGRRKTAVATVKLTSGNGVIVIDGKPIEERFTRVQERNVILNPMMVTDTMGKYNAVIKVLGGGVAGQSGAIAHGIARALEKSDDKLRATLKSNGLLTRDDRTKERKKPGLKRARKAPQYTKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MATRX_MEASB
Sequence: MTEIYDFDKSAWDIKGSIAPTQPTTHSEGRLVPQVRVIDPGPGDRKDECLMYMSLLGVVEDSDPLGPPIGRAFGSPPLGVGRSTAKPEELLKEATELDIVVRRTAGLNEKLVFYNNTPLTLPTPWRKVPTTGSVFNANQVCNAVNLTPLDTPQRFRVVYTSITRLSDNGHYTVPRRMLEFRSVNAVAFNLLATLRIDKAIGHGKIIDNAEQLPEATFMVHIGNFRRKKSEVYSADHCKMEIEKMGLVFALGGIGGTSPHIRSTGKMSKTLHAQLGFKKTLCYPLMDINEDLNRLLWRSRCKIARIQAVLQPSVPQEFRIYDDVIINDDQGLFKALQTVVPSNA
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: EIF3K_NEMVE
Sequence: MAAEMRVTVSQLLKGIDRYNPENLKVLEHYVHLQVHENAYDLDANLAVLKLYQFNPAYSQTSVISQILLKALMNLPNADFIMCRCVIDDAIQQDLTIKKVILLAERLETCAFTSAWQFIKEEASLVDGVTGFHDAIRNYITYVIGVTYQTIEESLASELLGGLQGAQLQDWIKAKGWMSSDDGTIYVTNQEAHIKSKNIAEKIDFASVANIIAAAR
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM3B_CONST
Sequence: QNCCNGGCSSKWCKGHARCC
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (VGSC).  Potently displaces (125)I-TIIIA from native rat brain Nav1. 2/SCN2A (IC(50) is 5 nM) and muscle Nav1. 4/SCN4A (IC(50) is 3 nM) VGSCs.  Potently and irreversibly inhibits current through Xenopus oocyte-expressed Nav1. 2/SCN2A and Nav1. 4/SCN4A.
What are the official names of this protein?
Mu-conotoxin SIIIB.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DNLJ_FRAP2
Sequence: MTPSDFISIDYKTLTKAQLKSYIDDLAEYLGEQSYLYHTIDKPVITDSDYDKLFRLLQDLVDDNPQLKPSNSVLDRVGGEILAGFETIKHKKKMTSLANVFSLEELRDFYDKIEYDIELECEPKMDGLAISIFYKNGKFDYAVTRGDGIQGEKVSENVKTIRNVPLKLNTSNPPEELEVRGEIILDKQSFLSLNEYMQTHENKTFANPRNAAAGSIRMLDSKVVAKRPLKLYSYGIGYFSKDFVHPETQFELMNLLQSFGFTISDNMFLAKNFSEVEVYHHKMSHQRADLAYDIDGLVFKVNNIKLQDTIGYTARGPKWAIAYKFPAEEVESEVLNVEFQVGRTGAITPVARLKPVAVGGVIVSNATLHNINEIKRKDIRVGDRVIVRRAGDVIPEVVKSLPQYRKPDAQMVEMPTNCPVCDSAIENINDQAIYRCTGGWHCQAQTTERLKHFVSRKAMDIDKLGAKLIEQLVAADLIKYPADIYKLNFEQLTGLERMGAKSSQNVLDSITKSKEPSLARFIFAIGIKDVGEVSSEALANHFGSLESFREAKFEQLIEINDIGEIIAKNIVSFWQDSLNIQIVDELLGNSINIQNPEKIEQAHNESFTNKTIVITGTFENYNRTELTQLLKSMGAKVTSSVSKKTDMVICGDNAGSKLTKAQDLGVEVIFEEDLQNLL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MOAC_DELAS
Sequence: MSSLTHFDAQGQAHMVDVGAKPATHRIAVAEGRIIMQPATLAIIQSGTAKKGDVLGIARIAGIMAAKKTSDLIPLCHPLALTRVAVEFDLLSDVSSVRCVATVETVGPTGVEMEALTAVQVALLTVYDMCKAVDKGMVMEGIRVLEKLGGKTNPSR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: GSTO1_CAEEL
Sequence: MVLTGVTSKAIRKGDAEPPLSKGSFRVYNMRFCPWAERAMLYVAAKGIEAEVVNLNVTDKLEWYWTKHYQGKAPAVEHNGKVVIESGFIPEYLDDAFPETRILPTDPYEKVQQKLLADRLTAVAHAVPLLFAVMRDRTLKDEKQRKVFEVLKQAENLLANDFYAGSQPGYPDYLSFPFFEKIWWSASLDGVVDLPTIEFPGEEEYPKLTKWFQKMISSDVVQSVTQSLEHGAAFMNAYATHQELNYDLGL
What is the function of this protein?
Exhibits glutathione-dependent thiol transferase activity (By similarity).  Has dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid (By similarity).  Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) (By similarity).  Protects against environmental stress and oxidative stress (PubMed:17901115).
What are the official names of this protein?
Glutathione transferase omega-1, Glutathione-dependent dehydroascorbate reductase, Monomethylarsonic acid reductase, MMA(V) reductase.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Omega family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y046_METJA
Sequence: MLGLKIEDAIKYNEKLKKYVYKKGDKLRINFKDKEALIEYNKTVLKVLFDLDIEFHKNGLIPTPINRYLFIKSTFETLKELGIEKPTVLEIGTGHSAIISLLIKKFYNAEVYATEVDEEFIDFAKRNIEKNKLDIKIINSKGRAIEGIEELKDKKFDLIISYPPFYSKNSVASGRKFGGALAKNVELIGGGKFGEEFSFKIIEEGINFLNKKGVISLMMPKKPEKRRELIIKKMKEVGLDVEVDEIKTGNRLRYIIKGIKG
What are the official names of this protein?
Putative methyltransferase MJ0046.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: RECA_XENBV
Sequence: MANDENKQKALAAALGQIEKQFGKGSIMRLGENRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIASAQREGKTCAFIDAEHALDPVYAKKLGVDIDNLLCSQPDTGEQALEICDALSRSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKNSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGSVKNGDEVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINTFGELVDLGVKHKMVEKAGAWYSYNGDKIGQGKANATIYLKEHPEVSAELDKKLRELLLNNTGGFSSAVSDYVADYEDNGEEVKNEEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_BACAH
Sequence: MWNEFKKFAFKGNVIDLAVGVVIGAAFGKIVSSLVKDIITPLLGMVLGGVDFTGLKITFGKASIMYGKFIQTIFDFLIIAAAIFMFVKVFNKLTSKREEEKEEELPEPTKEEELLGEIRDLLKQQNSSKDRA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOXO_DROPE
Sequence: MMDSFAQDWPTLTHTDNGLAMDQLSGVVGGGDLPGDVGFEPQTRARSNTWPCPRPENFVEQADELDSTKASNQQLADSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPQDLWGFPVDYQNTTMTQAHAQALEELTGSMADELTLCNQQQQQFSAASGLPSQPPPPPYQPPQLQQQQQQQPSYSLNGPAPGGYQTLQPQSQSQCLLHRSLNCSCLHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGSSDLLVQQQQQQQLQQQQVKVEFEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYDGLLDINIPLANVSTNAPLVSLVNNSTTLSSSSSNLSGSTTTLSSSSLSAAVQLNQLQAQLQQQQQQQQQQQHLQQQQQQHHQHQQQLLLNNNNNNNNNNSSNSSLDLATQTAATNLNAARVQYSQPSVVTSPPSWVH
What is the function of this protein?
Transcription factor involved in the regulation of the insulin signaling pathway.  Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR.  Involved in negative regulation of the cell cycle, modulating cell growth and proliferation.  In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.  Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging.  Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis (By similarity).
What are the official names of this protein?
Forkhead box protein O.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation (By similarity).
Protein: AROK_METMP
Sequence: MRCSAVSLGSGTIINAIATGFGSAFGVDLKIKADVELIDNGKKIVNGISIDNPTLKPSLVERCVKNVFDHFEVDYSAKISTIGDIPIKSGLSSSSAASNAAVLATIGALGEKVDPDLVLDLAIKSSFEENLTVTGAYDDATASYFGGITVCNNMERKILKKDKFKEDIKVIVLMPEFKKNVDVNRMKLIKDYVDMAFEKCMNGDYYKALFLNGLLYSSALNFPSNISVDALEAGAITAGLSGTGPSYVALCYFEDEKNVENALKKYGETTITKPSNDGAKILY
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_METCL
Sequence: MDDNKSKALAAALSQIEKQFGKGSIMRMGDADIGEDLQVVSTGSLGLDIALGVGGLPRGRIIEIYGPESSGKTTLTLSAIAEMQKLGGVAAFIDADDALDPQYASKLGVNVPELLISQPDTGEQALEIADMLVRSGSVDIVVVDSVAALTPRAEIEGEMGDSHMGLQARLMSQALRKLTGNIKRTNTLVIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRTGAIKKGDEVIGSETKVKVIKNKVAPPFKQAEFDIMYGEGISRLGEIIELGTNLKLVEKSGAWYSYNGEKIGQGKENAKEFLRENPAIAAEIEAKIRDNSNVLADSMTAARSEDD
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YWO3_CAEEL
Sequence: MTAIRDNLCELKRLEIPRPKCQGMQFVATRGRQGFYRTIRENGAMYGIQLKPQGPKRPQLSSDLFNRPMTVPEENSEDVEEAQTSQPETRKVEMNNNNNYKISYTSRPPLPPQQPKQTYTLQRTTPQAQPTPQQPRMFSRSSGGITGAVNNRPQMVAQQREIAQK
What are the official names of this protein?
Uncharacterized protein AH9.3.
Protein: YCV2_SCHPO
Sequence: MNKLSCLYCRRRKIKCDKNRPCHNCFVAKRECIIAGDNRKKRHTKTYVEALESQLANMESTLAKIKVAPVEKIPSLLAGISFKDHLSASLPNKTSYEQADTNATSKSLVDLPVSLEVRGRNTVTFYGPTSIFGTSFTSSPRPPPSASIEDTYPIIHCLQLFFKWQYAQFLFIHRESFLFEYFHRSNDNMYCSEHLIYALCAIGCRSSEDSLLVNQADAFYKMAWDALESYGLENSHITSAQCLLCLGFYKIAMGNTSHGWLLCGMAFRMGQDLGFHLDPRDWHINNVPVVSEEQAALRSRIYWGCYVADVFVSFILGRPTTLSKSDTSVPTSDDLPDFSGIEDFMLERGGAHASSITISQLLNLIVSLSNITDAILLNVFAPYSTKYGIDLRLQNVGKYNLELMKWHFELPPNLSWKKTELRDFGQSPELCFLCLYFFLIRLCLNRPFLSKKGLYVNDMTPRNICIDSIEDVKVLIRAYRENLGLHHTPLIIVYACIVSCSTVFMLFDGATPSEIVALEQDIKFFLHVLTKISKNWDLASKSINLIQKKSTMYDTNARANDTDVDFSNDKQNTHDFQISHDENLIQLFNDESNFFNLNDLGDFQSIFGGPQF
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein C777.02.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.