PharMolix/UniProtQA huggingface dataset:
Protein: GUF1_DROME
Sequence: MIVGYSVFFHHTVTRRTWCAVTIFFCRQRNVNSAMIRAISIRWLLQRPGDKRHSAWLVARSKSLLVRNLSTTNQVKGETEEPSQADLLREFAHMPVERIRNFSIIAHVDHGKSTLADRLLELTGAIARNGGQHQVLDNLQVERERGITVKAQTASIFHRHKGQLYLLNLIDTPGHVDFSNEVSRSLAACDGVVLLVDACHGVQAQTVANYHLAKQRQLAVVPVLNKIDIKHANPDQVCQDLKLLFGIDPDEVLRVSAKLGTGVSEVLERVIETVPPPQVQRDSDFRALIFDSWFDKYRGALNLIYVLNGKLEQNQDIQSLATKKVYSVKSISVLRPAECPVPDVSAGQVGLIACNMRNSKESIVGDTIHLKNQAVAAAGSYRPQQPLVFAGVFPADQSKHVALRSAIDKMVLNDSAVTVKIDSSPALGQGWRLGFLGLLHMEVFCQRLEQEHGAEPIITAPSVTYRLVLSNPKMIKQQGRDTMDISNAALFPEPHSIKEYYEPLVLGTIITPTEYVGQVISLCVERRGLQQSSVNIDDTRVLMKYVLPLSEIILDFHDRLKSLSSGYASFSYEDHGYHPSHLVRLDIHLNGKPVEELCRIVHVSKATGVARQMVLKLRELIPKQMVQIAIQACVGSKVLARETIKAYRKDVTAKLYGGDVTRRMKLLKQQAEGKKKMRMFANIRVPHETFINVLKR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor waclaw, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: CARB_AGARV
Sequence: MPRNNDIKKVLVIGSGPIVIGQAAEFDYAGTQACRSLKEEGIEVCLVNSNPATIMTDKQIADQVYIEPLTLESLKEIIIKEKPDSILPTLGGQAGLNLGMELAECGFLDEQGVKLIGTTAETIFKAEDRQAFKDTMEKIGEPIAASQVVKNIEDGIAFTNKIGYPVVLRPAFTLGGSGGGIAHDEQELIDILSNGLRLSRVGEVLVERCIAGWKEIEYEVMRDANGNCITVCNMENIDPVGVHTGDSIVVAPSQTLGDKEYQMLRTSALNIINELQITGGCNVQYALNPDSFEYCVIEVNPRVSRSSALASKATGYPIAKVTAKIALGYHLDEIKNAITQKTYASFEPMLDYCVVKIPRLPFDKFLTAKRTLTTQMKATGEVMSICNNFEGALMKAIRSLEQHVDSLMSYDFTGLTDDELEKQLAVVDDRRIWVIAEALRRGVKYEHIHEITKIDLWFIDKIAILVEMENRLKTEELTVDLLKEAKRIEFPDNVISQLTDIDEADIKKMRYDNGIVAAYKMVDTCAAEFEAETPYYYSVFGSENEAAETNPQKKVLVLGSGPIRIGQGVEFDYCSVHCTWSFAKEGWETIIVNNNPETVSTDFDIADKLYFEPLTAEDVESIVNIEKPDGAVVQFGGQTAIKLTEALMKMGVKILGTKAEDVDAAEDRELFDEILQKTGIPRAAGGTVFTAEEAKKVANEIGYPVLVRPSYVLGGQGMKIAWNDDEIEEFIGIINTITQDHPILVDKYLMGKEIEVDAICDGTDILIPGIMEHIERTGVHSGDSISVYPAHTISEKAKETLVEYTKRLAQALHVVGMINIQFIDMDDNIYVIEVNPRSSRTVPYISKVTGIPIVDLAARIIMGETIKGMGYTPGLAPTADYIAIKMPVFSFEKLRGAEISLGPEMKSTGECLGIDKTFNGALYKAFEGAGVELPKYKQMIMTVKDADKPEAVGVAKRFEKLGYKIYATRSTAKYLQEHGVNALRVNKISQESPNVMDLILGHKIDLVIDTPTQGNGDKTRDGFLIRRNAIETGVYCITAMDTANALAHALETASDKKTPVDIATVKNL
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RL14_RUMCH
Sequence: MIQVQSRMKVADNTGAKELMCIKVLGGSWRKYANIGDVVVASVKNATPGGVVKKGDVVKCVIVRSKKGVRRPDGSYIRFDENAAVIIKDDKNPRGTRIFGPVARELREKNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: APEA_BORGP
Sequence: MKKQNPWISLSEEEKNQIFNFSESYKKFISKFKTEREVTSYALDKAKKRGFIDAEEKKNLIPGDKIFYTCREKSVAFAIIGKNPIENGMNLIVSHTDSPRLDAKPSPISEENELAFLKTNYYGGIKKYQWLSTPLSIRGVVFLKNGEKVEINIGDNENDPVFVIPDILPHLDKKIQRNKKSDEIIEGENLKILIGSLPIESKEQDKVKLGTLQLIKEKYKIEEEDFVSSEIEIVPAGTAKDVGFDKALIGAYGQDDKICAYASLEAIFDLEEIPSKTAICFLVDKEEIGSTGSTGLDSRYLEYFVSDMIFKIKKSEYNNLQVQKALWNSKSISADVCAAINPIFNSVHDAQNAPKLGYGIPIMKYTGHGGKVMASDADAELVSYIRQLLNKNNIAWQVATLGKVEEGGGGTVAKFLASYGIRTIDMGPAVISMHSPMEITSKFDLYNAYLAYKAFYKE
What are the official names of this protein?
Probable M18 family aminopeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: UVRC_STRP3
Sequence: MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCFYYHLGQCCAHTICHTDKVYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLKIDKPVRIEAFDNSNIQGTSPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFAP1_HUMAN
Sequence: MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSLKGKKPPVASNGVTGKGKTLSSQPKKADPAAVVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKALAGGVTLGLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKKSQAAPGSSPCRGHVLRKAKEWELKNGT
What is the function of this protein?
Can cross-link actin filaments into both network and bundle structures (By similarity).  May modulate changes in actin filament integrity and induce lamellipodia formation.  May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton.  Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
What are the official names of this protein?
Actin filament-associated protein 1, 110 kDa actin filament-associated protein, AFAP-110.
Protein: LCP1_DROME
Sequence: MFKFVMICAVLGLAVANPPVPHSLGRSEDVHADVLSQSDDVRADGFDSSLHTSNGIEQAASGDAHGNIHGNFGWISPEGEHVEVKYVANENGYQPSGAWIPTPPPIPEAIARAVAWLESHPPAPEHPRHH
What is the function of this protein?
Component of the larval cuticle.
What are the official names of this protein?
Larval cuticle protein 1, Larval cuticle protein I.
Protein: SCPA_STRGC
Sequence: MDIKIKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVATLQAMRLEVAGEYMVMASQLMLIKSRKLLPKVVDDADLEEDLEHDLLSQIVEYRKFKLLGEKMAEQHEERALYYSKPKIELVYEDAELVHDRSAIDLFLAFSGLLAKKREEFRHSHTTIVKDEYKIEDMMDVVLERCKSQKKLALQELFTETKDMNEVITLFLATLELVKVQEIQLFQEENFGSIYLIRK
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: VINEX_HUMAN
Sequence: MQGPPRSLRAGLSLDDFIPGHLQSHIGSSSRGTRVPVIRNGGSNTLNFQFHDPAPRTVCNGGYTPRRDASQHPDPAWYQTWPGPGSKPSASTKIPASQHTQNWSATWTKDSKRRDKRWVKYEGIGPVDESGMPIAPRSSVDRPRDWYRRMFQQIHRKMPDLQLDWTFEEPPRDPRHLGAQQRPAHRPGPATSSSGRSWDHSEELPRSTFNYRPGAFSTVLQPSNQVLRRREKVDNVWTEESWNQFLQELETGQRPKKPLVDDPGEKPSQPIEVLLERELAELSAELDKDLRAIETRLPSPKSSPAPRRAPEQRPPAGPASAWSSSYPHAPYLGSARSLSPHKMADGGSPFLGRRDFVYPSSTRDPSASNGGGSPARREEKKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVEVLPADEIPKPIKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSSPSALRSPADPIDLGGQTSPRRTGFSFPTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV
What is the function of this protein?
Vinexin alpha isoform promotes up-regulation of actin stress fiber formation.  Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain.
What are the official names of this protein?
Vinexin, SH3-containing adapter molecule 1, SCAM-1, Sorbin and SH3 domain-containing protein 3.
What are the subcellular locations of this protein?
[Isoform Alpha]: Cell junction. Cytoplasm, cytoskeleton. Note=Localized at cell- extracellular matrix junctions (By similarity). Both isoforms were localized at focal adhesion and cell-cell adhesion sites. SUBCELLULAR LOCATION: [Isoform Beta]: Cell junction. Nucleus. Cytoplasm, cytoskeleton. Note=Localized at cell- extracellular matrix junctions (By similarity). Both isoforms were localized at focal adhesion and cell-cell adhesion sites, vinexin beta was also found in the nucleus.
Protein: 3BP5L_XENLA
Sequence: MEGKEGPPCEVRLPTPGAEREGPVHPELGAFGESASDAIKLSETSNDAKKEEIEEELDPRIQEELERLNQASEEINLLELQLDEARTAYRRILTESARRLNGLATQLGACIDKARPYYEARRLAKEAQQDTHSAALRYERAVSMHAAAREMVFVAEQGVTADKNRLDPTWQEMLNHATCKVNEAEEERLRSEFEHQRVTRLCHEAEAKVQTLQKSLKRLIIKSRPYFELKAQLNTILEEHKSRVTLLENSVAQAKLRYSGTLHNLEKISEEIHARRTQSSVLSQRAPPLGAEAPPSVKDGETGPPADTVSLLSLQTIASDLQKSDSVEHLRDLTDVTSLDGRETGAVESGGSRERGEDRGTGGAFRHHRSVSL
What is the function of this protein?
Functions as guanine nucleotide exchange factor (GEF) for rab11a.
What are the official names of this protein?
SH3 domain-binding protein 5-like, SH3BP-5-like.
What is the protein family that this protein belongs to?
Belongs to the SH3BP5 family.
Protein: JIP5_AJECN
Sequence: MFDNVCSLPLSSDLFAQAIHPTEPLVAVGLSSGHVQTFRIPPSSDSGPGATKNGLGHIDTAWRTRRHKASCRCLGFGIDGQTLYSAGADGWVKAAKAETGVVNLKIAVPRLGEGTHDRIDPPTVIHAISPETIILSTDSGALHLFDLRVPPSPVSQRPQQTHHPHDDYVSSLTPLPPSETSTSGFSKQWVTTGGTTIAVTDLRRGVLVRSEDQDEELISSVYVTGLKAGGTSRGEKLVVGGASGVLTLWEKGAWDDQDERIIVDRQPDGGESLEILSLLPDSIGAGKVVAVGQSDGAVQFVQLGVNKVISKVVHDELEGIAGLGFDVGGRMISGGGSIVKVWHEAVEREGHGENEEDEQHSRKRFVMGSDDDGNDDSSVDGQKQNKKKRKKRKKGKSKDKSDGQHVMAFKGLD
What are the official names of this protein?
WD repeat-containing protein JIP5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SLK_CAVPO
Sequence: MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEEFWETIGELGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTIDSNKPIRELIAEAKAEVTEEVEDGKEEDDDEEIENSLPIPTNKRASSDLSIASSEEDKLSQNACILESVSEKTEHNASGDKFSTKVLNEKPCPGEPENAVELVGGAVAVLPDRATELPESGREEKRPKLDRLPDTEDQEMADINSVSEGEEDHAVTSETNIEHNLKPEKERDQEKQPVLENKLVKSEDTTIQTVDLVSQETGEKEVDIHILDSEVVHAVEDTHEKLRKDDTTQKDVISDTSSVGERDEEIGAVPKTAESSAEGAQGDGGKETDEGAQILISKATEGPKASGTEEAPPVTEITETNDTDQKLVENTHEKQLPISSETTLDTSEGLGASEGREVTESGSTEEVEVEGAVSETDEEDVQSETRGAPMAVTQMDTEKNETPHEAPAQVEVQVPVPPQPSEPPPAPIPSININSEAAENKGEMGASLNTETILLPESESQKENDTDSGTGSTADNSSIDLNLSISSFLSKTKDNGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKEEQRAQQQLNGKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRLRDEAKRIKGEQEKELSKFQNILKNRKKEVLNEVEKAPKDLRKELMKRRKEELAQSQHVQEQDFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKHQLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAKTRMAMFKKSLRINSTATPDQDRDKIKQFSAQEEKRQKNERMAQHQKHENQMRDLQLQCEANVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQEVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS
What is the function of this protein?
Mediates apoptosis and actin stress fiber dissolution.
What are the official names of this protein?
STE20-like serine/threonine-protein kinase, STE20-like kinase, STE20-related serine/threonine-protein kinase, STE20-related kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBF_SYNP2
Sequence: MTSGPNQPVSYPIFTVRWLAVHTLAVPSVFFLGAIAAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: QACE_KLEAE
Sequence: MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFYFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIVSGVVVLNLLSKASAH
What is the function of this protein?
Multidrug exporter.  Is implicated for the resistance to bacteriocidal quaternary ammonium compounds (By similarity).
What are the official names of this protein?
Quaternary ammonium compound-resistance protein QacE, Quaternary ammonium determinant E.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FMT_BORRA
Sequence: MRIFFASSDGIALEVLKKISDQYDVVGVLTAPDKPSGRGLSLKVNDIKREALSRKITVLQPVVLDADVINLVKSLEPELMLVFSYGKIFKQEFLDIFPVGCINIHPSLLPKYRGPSPIQTVILNGDSVSGITVQKMTLEMDSGNILAQSQFEIKSFNTSVDIFEYVSLNSFDLVIEALNKLLKGDIGIVQDKNNATYCSFLGKEHRTIDFKLSAFDIKNKINAYNPWPLARARLDNNEIIFYRADFISTNDYDDQVIGKIIAFDPSKGLLVKTGDGILVVLELQRIGKKVLDCVSFYHGNRDLIGKVFS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: TBCC1_MOUSE
Sequence: MDQSGVLLWVKAEPFLVGALQEPPPSKFSLHYLRKIATYVRTRATEGAYPHLYWPTWRHIACGKLQLAKDLAWLYFEMFDNLSVRTPEERLEWSEILSNCATEEEVEKQRSQLYVDTLQFLLFLYIQQLNRISLRTSLIGEEWPSRRSRPQSPSPAERPSCHNKNWNDYSHQAFVCNHLSELLELLLDPEQLTASFHSTHSSLLSRDAVTALSFLIEGTVSRAKKVYPLHQLALWQPLHVASGFSKSSKTFSLYKLEAWLRASLTTNPFGPSACLKSGKKLAWAHQVEGSTKRAKIACNAHMAPRLHRIVVMSQVYKQTLAKSSETLVGAHVRAHRCSESFIYLLSPLRSMTIEKCRNSTFVLGPVETTLHLHDCENLKVIAVCHRLSISSTTSCTFHIMTPSRPLILSGNQTVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMVVCKEGSVTSLFRLLPPSEFYIFVIPFEMEGDTAEIPGGLPSAYQKALAQREESIHIWQKTVKEARLTKEQRKQFQALVENKFYEWLVSTGHRQQLDSLVPTPAAS
What is the function of this protein?
Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration.
What are the official names of this protein?
TBCC domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TBCC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes at the spindle midzone, midbody and basal bodies of primary and motile cilia.
Protein: RSMJ_PSEAE
Sequence: MTDSAAPRLHVQALSADCAEAARRWAERLGLPLAADDEAEFAVQVGEQGLQVLQLGADSPGPVRVDFVEGASAHRRKFGGGSGQMIAKAVGVQPGIRPRVLDATAGLGRDGFVLASLGCEVTLVERQPLIAALLEDGLERARRDPDVAPIAARMRLLGGNSADLMRAWDGEAPQVVYLDPMFPHRDKSALVKKEMRLFRPLVGDDLDAPALLQAALALASHRVVVKRPRKAPIIEGPKPGYSLEGKSSRYDIYPKKALGKG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_XYLFT
Sequence: MVIINTAAYHFVSITQPQTLADQIRAHGEIAGLKGTVLIANEGINLFLAGEKEAINAFYAWLCADVRFAALHVKYSVSAYKPFARFKVKVRPEIISFRRGDISPLQVRAPGVSAHTLRDWLRRGCDDNGRRLVMLDARNQQEIAYGTFSGAMTLPITKFTGFPGALAHYRDLLSDATVVSFCTGGIRCEKAVLWMRADGMDNVLQLEGGILGYFEQVGGEGYDGRCFVFDKRVALDPQLRPLYDMRVVASFARSEIS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: GRLC_DICDI
Sequence: MKMKIIFLILILIFSINIIKCDKEFKMLTLLTAQVDDLGFNNMINQGRIEVAKGMNIEDSRLLVVEGFNETFKHLLPIVQNDDIDLVICSSSGHLQACRAIAEMYINSTTIKTQFLVRGSSSPTRNLIYISYNYASANYISGYFAALFSKTGKIGFVSPGQAANNNDSFVYAFWVGARQVNPDIKFYYYNIGNYLDVDKTVAATNDLLDMGCDVVGNTLDDFSTGDASIARGFPAIGTNGFPQRHVYGENVIYSYSYNWTKFFLPIAESVKSGNTNNSQWYADFDFDENKNFYHLDYGFEVNQSILDKMNTEIDYLKSTDRMSHPYYCNELIPQYAKENNLKLANVTGITLPIGCVTHQTFLSINKPFPGMTYLGNYKIKLVEVEFSQSLQYGFSITTGVLIAITIIMMLGIVRYKSTPSIRSASPIFLNFILAGGIIVYIGIIVWVGPANDHQCNARLWLVTLGFSTLIGSLVVKNFRIWLIFDNPELKSISITNYQLFPWVGACLVINIILMSILTSVGDLREIDAQGIDSLGKYEFMKVCKMNSSGASTLYTILAYFAALLLVGVFVSWKIRIVDIQEFNESKAIANTLYAISFCLFVIVPLMISPQDKQSETIVLCTAGLFITTAALLIIFTPKFWRVFTLGDGGTNDMFRKKQSNVATARAESSKSSSGPKLNRRGNLVSDDFTDTETSISEKKVNVVAGAVLAEFTDDTISEFDDNNIEQDNDNDNDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTSQPNDEKVEEKQQNDTEEEDKNQ
What are the official names of this protein?
Metabotropic glutamate receptor-like protein C.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GSA_CAMJR
Sequence: MTNKKAFKEACKFIAGGVNSPVRAFANVQSEPKFISHGKGAYIFDIDGNSYIDYVQSWGPLLFGHCDKDIQKACQKALHKGSSFGAPTLLETELAKLVLSDFPHLEKIRFVSSGTEATMSAIRLARGFTKKDKILKFEGCYHGHSDSLLVSAGSGAATFNSPSSLGVLEDVAKHTLVAKYNDINSVKELFEKNKDIACVIIEPIAGNMGLVPAKQDFLEELAKICKNNQTLLIFDEVMSGYRASYLGSYGINHIQADIITFGKVIGGGLPAAAFASRAEIMDILSPLGGVYQAGTLSGNPLAMAAGIASLTKAKKKTKLYDKLGKLAKKLTQGMKKLADEKGLPLQVCHVGSMFGYFFTKDPVSNYQDALKSDLALFSKFHKNMLENGIYLAPSQFETGFICSKMDDKIIDTTLEAVRESFKRI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YK6B_CAEEL
Sequence: MDLFDLIFPPPPQSPSKLHPTQNHILPPEPLNRDFGDTRKNHKKAQPRRTTKAPSTSSPTIHDRQTPPRPTTPKSPTEKLLPIYHKFADGTEVVNPAAYAQRGFGWVKQNNTARVSWAKWAQSTKKCDDDIYGLKWIEERYPNWRDSNFRIRERRRSRSRSPQLSDNGSEDISIYLGRANSSSPNPTATGSETSYGSPTDAIYIPRNY
What are the official names of this protein?
Uncharacterized protein C29E4.11.
Protein: HBAE_ORYLA
Sequence: MTSLSAKDKDVVKAFWAKISSKATDIGADALGRMLVVYPQTKTYFAHWKDLSPGSAPVKKHGQTVMGGVAEAVGKIDNLTAGLLNLSELHAFTLRVDPANFKILSHNILVVLAIMFPNDFTPEVHVAMDKFLAALALALAEKYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin embryonic subunit alpha, Alpha-globin, embryonic, Hemoglobin alpha-chain, embryonic.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RGS3_CAEEL
Sequence: MWRSYKAETPELADETQEVDLNLHDSSESDHEGRQSRSASITSSTSAPASNDVTLQVPITNSSATSPTPSTGSMYFIAGMFDGKEKVNREQPPMPTTDGVEYPRAASWAAGNCANVLNDDKGKQLFRVFLFQSLAEENLAFLEAMEKLKKMKISDEKVAYAKEILETYQGSINLSSSSMKSLRNAVASETLDMEEFAPAIKEVRRLLENDQFPRFRRSELYLEYLEELLPRSYAEKWAQSFEGLLGNHVGRHHFRIFLRSIHAEENLRFWEAVVEFRSSRHKANAMNNLGKVILSTYLAEGTTNEVFLPFGVRQVIERRIQDNQIDITLFDEAIKHVEQVLRNDPYVRFLQSSQYIDLLSKLK
What is the function of this protein?
Modulates chemotaxis responses by regulating positively the sensitivity to CO2 levels in BAG neurons and by regulating negatively the sensitivity to quinine in ASH sensory neurons.
What are the official names of this protein?
Regulator of G-protein signaling rgs-3.
Protein: LOVD_ASPTE
Sequence: MGSIIDAAAAADPVVLMETAFRKAVKSRQIPGAVIMARDCSGNLNYTRCFGARTVRRDECNQLPPLQVDTPCRLASATKLLTTIMALQCMERGLVDLDETVDRLLPDLSAMPVLEGFDDAGNARLRERRGKITLRHLLTHTSGLSYVFLHPLLREYMAQGHLQSAEKFGIQSRLAPPAVNDPGAEWIYGANLDWAGKLVERATGLDLEQYLQENICAPLGITDMTFKLQQRPDMLARRADQTHRNSADGRLRYDDSVYFRADGEECFGGQGVFSGPGSYMKVLHSLLKRDGLLLQPQTVDLMFQPALEPRLEEQMNQHMDASPHINYGGPMPMVLRRSFGLGGIIALEDLDGENWRRKGSLTFGGGPNIVWQIDPKAGLCTLAFFQLEPWNDPVCRDLTRTFEHAIYAQYQQG
What is the function of this protein?
Monacolin J acid methylbutanoyltransferase; part of the gene cluster that mediates the biosynthesis of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR) (PubMed:10334994, PubMed:12929390, PubMed:21495633).  The first step in the biosynthesis of lovastatin is the production of dihydromonacolin L acid by the lovastatin nonaketide synthase lovB and the trans-acting enoyl reductase lovC via condensation of one acetyl-CoA unit and 8 malonyl-CoA units (PubMed:10334994, PubMed:10381407, PubMed:19900898, PubMed:22733743).  Dihydromonacolin L acid is released from lovB by the thioesterase lovG (PubMed:23653178).  Next, dihydromonacolin L acid is oxidized by the dihydromonacolin L monooxygenase lovA twice to form monacolin J acid (PubMed:12929390, PubMed:21495633).  The 2-methylbutyrate moiety of lovastatin is synthesized by the lovastatin diketide synthase lovF via condensation of one acetyl-CoA unit and one malonyl-CoA unit (PubMed:19530726, PubMed:21069965).  Finally, the covalent attachment of this moiety to monacolin J acid is catalyzed by the transesterase lovD to yield lovastatin (PubMed:10334994, PubMed:17113998, PubMed:18988191, PubMed:19875080, PubMed:24727900).  LovD has broad substrate specificity and can also convert monacolin J to simvastatin using alpha-dimethylbutanoyl-S-methyl-3-mercaptopropionate (DMB-S-MMP) as the thioester acyl donor, and can also catalyze the reverse reaction and function as hydrolase in vitro (PubMed:19875080).  LovD has much higher activity with LovF-bound 2-methylbutanoate than with free diketide substrates (PubMed:21069965).
What are the official names of this protein?
Monacolin J acid methylbutanoyltransferase, Lovastatin biosynthesis cluster protein D, Lovastatin hydrolase, Simvastatin synthase LovD, SV synthase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: MERC_ACIFR
Sequence: MSAITRIIDKIGIVGTIVGSFSCAMCFPAAASLGAAIGLGFLSQWEGLFVQWLIPIFASVALLATLAGWFSHRQWQRTLLGSIGPVLALVGVFGLTHHFLDKDLARVIFYTGLVVMFLVSIWDMVNPANRRCATDGCETPAPRS
What is the function of this protein?
Involved in mercuric ion uptake.
What are the official names of this protein?
Mercuric transport protein MerC, Mercuric resistance protein MerC.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.