PharMolix/UniProtQA huggingface dataset:
Protein: DER_NEIG2
Sequence: MKPTIALIGRPNVGKSTLFNRLTRTKDALVHDLPGLTRDRHYGHGKVGSKPYFVIDTGGFEPVVDSGILHEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKIIADRLRQSPRPVYLAVNKGEGGDRAVLAAEFYELALGEPHVISGAHGDGVYYLIEEILENFPEPEAEEADAKHPVFAVIGRPNVGKSTLVNAILGEKRVIAFDMAGTTRDSIHIDFEREGKPFTIIDTAGVRRRGKVDEAVEKFSVIKAMQAVEAANVAVLVLDAQQDIADQDATIAGFALEAGRALVVAVNKWDGISEERREQVKRDISRKLYFLDFAKFHFISALKERGIDGLFESIQAAYNAAMIKMPTPKITRVLQTAVGRQQPPRAGLVRPKMRYAHQGGMNPPVIVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQYNVSENPYENAEDKPKKKPLRRVSLSNRIEKREGRKEEKNRFKKKTKVSVKKQFSK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ASSY_RHIME
Sequence: MASHKDVKKVVLAYSGGLDTSIILKWLQTELGAEVVTFTADLGQGEELEPARKKAEMLGIKEIYIEDVREEFVRDFVFPMFRANAVYEGVYLLGTSIARPLISKHLIDIARKTGADAIAHGATGKGNDQVRFELSAYALNPDIKIIAPWRDWSFKSRTDLLEFAEKHQIPVAKDKKGEAPFSVDANLLHSSSEGKVLEDPAREAPEYVHMRTISPEAAPDKATVIKVGFERGDAVSIDGVRMSPATLLAKLNEYGRDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRAIESITLDRGAAHLKDELMPRYAELIYYGFWFSPEREMLQAAIDRSQEHVEGEVTLKLYKGNVMVIGRESGKSLYSDKLVTFEDDQGAYDQKDAAGFIKLNALRLRTLAARNR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_HELPJ
Sequence: MSILAEKLSSILKRYDELTALLSSVEVVSDIKKLTELSKEQSSIEEISVASKEYLSVLEGIKENKELLEDKELSELAKEELKILEIQKSELETAIKQLLIPKDPNDDKNIYLELRAGTGGDEAGIFVGDLFKAYCRYADLKKWKVEIVSSSENSVGGYKEIIVLIKGKGVYSRLKFEAGTHRVQRVPETESQGRIHTSAITVAIMPEVDDVEVSINPSDLKIEVFRAGGHGGQCVNTTDSAVRITHLPTNISVSMQDEKSQHKNKDKALKILKARLYEKQIEEQQLANAKDRKEQVGSGDRSERIRTYNYPQNRLSEHRINLTLYSLEEIMLSGNLDEVINPLIAHAQSQFE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_SHIF8
Sequence: MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLEEGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLDGQVIKKVDLTTRSIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CTEFA
Sequence: MTNTRKSHPLIKIVNHSFIDLPAPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMTTLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASMTYFFIILILMPSTALMENKLLQW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GUAA_YERPP
Sequence: MTKNIHKHRILILDFGSQYTQLLARRVREIGVYCELWAWDVTEAQIREFNPSGIILSGSPESTIENGSPRAPDYVFTAGVPVLGVCYGMQTMAIQLGGKVESSNQREFGYAQVEIKADSALIRDIKDAINPAGEAVLDVWMSHGDKVAEIPADFVTVASTDTCPFAIMANEEKRFYGVQFHPEVTHTKQGLRLLERFVLGICGCEALWTSATIIEDAIVRLREQIGDDHVILGLSGGVDSSVTAMLLHRAIGKRLTCVFVDNGLLRLNEADQVLEMFGDKFGLNIVHVAAEDRFLSALTGVDEPEAKRKIIGRVFVELFDEEACKQEQVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PI42C_BOVIN
Sequence: MASSSVPPTAVPAATAAPGAGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRSPPTESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDSEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKVFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEDGPVREEESEGDGDCGLTGPPAPVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIFA
What is the function of this protein?
Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity.  May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity.  PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism.  They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3.
What are the official names of this protein?
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, Phosphatidylinositol 5-phosphate 4-kinase type II gamma, PI(5)P 4-kinase type II gamma, PIP4KII-gamma.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Cytoplasm.
Protein: AI5L7_ARATH
Sequence: MGTHINFNNLGGGGHPGGEGSSNQMKPTGSVMPLARQSSVYSLTFDELQNTLGGPGKDFGSMNMDELLKSIWTAEEAQAMAMTSAPAATAVAQPGAGIPPPGGNLQRQGSLTLPRTISQKTVDEVWKCLITKDGNMEGSSGGGGESNVPPGRQQTLGEMTLEEFLFRAGVVREDNCVQQMGQVNGNNNNGFYGNSTAAGGLGFGFGQPNQNSITFNGTNDSMILNQPPGLGLKMGGTMQQQQQQQQLLQQQQQQMQQLNQPHPQQRLPQTIFPKQANVAFSAPVNITNKGFAGAANNSINNNNGLASYGGTGVTVAATSPGTSSAENNSLSPVPYVLNRGRRSNTGLEKVIERRQRRMIKNRESAARSRARKQAYTLELEAEIEKLKKTNQELQKKQAEMVEMQKNELKETSKRPWGSKRQCLRRTLTGPW
What is the function of this protein?
Functions as transcriptional activator in the ABA-inducible expression of LTI65/RD29B (AC Q04980).  Binds specifically to the ABA-responsive element (ABRE) of the LTI65/RD29B (AC Q04980) gene promoter (PubMed:11005831, PubMed:11884679, PubMed:15361142, PubMed:16463099).  Binds to the promoter of FREE1 and activates its transcription (PubMed:32540007).
What are the official names of this protein?
ABSCISIC ACID-INSENSITIVE 5-like protein 7, ABA-responsive element-binding protein 2, Abscisic acid responsive elements-binding factor 4, ABRE-binding factor 4, bZIP transcription factor 38, AtbZIP38.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ABI5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SFP1_BOVIN
Sequence: MALQLGLFLIWAGVSVFLQLDPVNGDQDEGVSTEPTQDGPAELPEDEECVFPFVYRNRKHFDCTVHGSLFPWCSLDADYVGRWKYCAQRDYAKCVFPFIYGGKKYETCTKIGSMWMSWCSLSPNYDKDRAWKYC
What is the function of this protein?
Could enhance the fertilizing capacity of bull spermatozoa upon interaction with heparin-like glycosaminoglycans present in the female genital tract.  Exhibits both simulatory and inhibitory actions on the release of pituitary gonadotropins.
What are the official names of this protein?
Seminal plasma protein PDC-109, BSP-A1 and BSP-A2, Seminal vesicle secretory protein 109, SVSP109.
What is the protein family that this protein belongs to?
Belongs to the seminal plasma protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNMG_ALISL
Sequence: MFYQENFDVIVIGGGHAGTEAALAAARTGQKTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAEAIDHSGIQFRTLNASKGPAVRATRAQADRALYKTYVRSVLENQPNLTLFQQAVDDLIIENDKVIGAVTQMGLKFRAKSVVLTAGTFLGGQIHIGMENFSGGRAGDPSSITLAQRLRDRPFRIDRLKTGTPPRIDARSVDFSNLEAQPGDNPTPVFSFLGNRQQHPQQVNCFITHTNEKTHDVIRKNLDRSPMYAGVIEGIGPRYCPSIEDKVMRFADKDSHQIFIEPEGLTTHELYPNGISTSLPFDVQLQIVRSMKGFENAHIVRPGYAIEYDFFDPRDLKATYETKFIEGLFFAGQINGTTGYEEAAAQGLMAGLNASLFSQGKEGWSPRRDEAYMGVLIDDLSTLGTKEPYRMFTSRAEYRLSLREDNADLRLTEQGRELGLVDDIRWSRFNEKVENIEKERQRLKDIWINPTSENIDQVNSILKTPIVREASGEDLLRRPEVTYSSLMTIEKFGPASDDQQASEQVEIQTKYAGYIQRQRDEIEKSLRHENTKLPFDLEYNKVKGLSNEVVAKLSDAKPESIGIASRISGITPAAISILLVHLKKHGLLKKGK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_LISMC
Sequence: MFRTMMNGKIHRATVTEANLNYVGSITIDSAILEAVDMLPNEKVQIVNNNNGARIETYIIPGEPGSGVICLNGAAARHVQVGDVVIIMSYGMFTTEEAKTHEPKIVVLDEKNHIEMILPEEKAHTTL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACO2M_ARATH
Sequence: MYRRATSGVRSASARLSSSLSRIASSETASVSAPSASSLRNQTNRSKSFSSALRSFRVCSASTRWSHGGSWGSPASLRAQARNSTPVMEKFERKYATMASEHSYKDILTSLPKPGGGEYGKYYSLPALNDPRIDKLPFSVRILLESAIRNCDNYQVTKDDVEKILDWENTSTKQVEIAFKPARVILQDFTGVPVLVDLASMRDAVKNLGSDPSKINPLVPVDLVVDHSIQVDFARSEDAAQKNLELEFKRNKERFTFLKWGSTAFQNMLVVPPGSGIVHQVNLEYLGRVVFNSKGFLYPDSVVGTDSHTTMIDGLGVAGWGVGGIEAEAAMLGQPMSMVLPGVVGFKLDGKLKEGVTATDLVLTVTQILRKHGVVGKFVEFYGEGMSELSLADRATIANMSPEYGATMGFFPVDHVTLEYLKLTGRSDETVSMIESYLRANNMFVDYNEPQQERAYTSYLQLDLGHVEPCISGPKRPHDRVPLKDMKADWHACLDNPVGFKGFAVPKEKQEEVVKFSYNGQPAEIKHGSVVIAAITSCTNTSNPSVMIGAALVAKKASDLGLKVKPWVKTSLAPGSRVVEKYLDRSGLRESLTKQGFEIVGYGCTTCIGNSGNLDPEVASAIEGTDIIPAAVLSGNRNFEGRVHPQTRANYLASPPLVVAYALAGTVDIDFEKEPIGTRSDGKSVYLRDVWPSNEEVAQVVQYSVLPSMFKSSYETITEGNPLWNELSAPSSTLYSWDPNSTYIHEPPYFKNMTANPPGPREVKDAYCLLNFGDSVTTDHISPAGNIQKTSPAAKFLMDRGVISEDFNSYGSRRGNDEVMARGTFANIRIVNKLLKGEVGPNTVHIPTGEKLSVFDAASKYKTAEQDTIILAGAEYGSGSSRDWAAKGPLLLGVKAVIAKSFERIHRSNLAGMGIIPLCFKAGEDAETLGLTGHERYTVHLPTKVSDIRPGQDVTVTTDSGKSFVCTLRFDTEVELAYYDHGGILPYVIRSLSAK
What is the function of this protein?
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.  Contributes to oxidative stress tolerance (PubMed:17013749).  Involved in acetate assimilation (PubMed:25061985).
What are the official names of this protein?
Aconitate hydratase 2, mitochondrial, Aconitase 2, mACO2, Citrate hydro-lyase 2.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MGT4C_PIG
Sequence: MFKFHQVKHIFEILDKMRCLRKRFTVSFLGVLVIFLLFMNLYIEDSYVLEGDKQLVRETSIHQLNPERYVHTFKYLSNFSGTINVTYRYLAVMPFQRKRFLTIGLSSVRRKKGNYLLETIKSIFEQSSYEELKEISVVVHLADFNSSWREVMVQDITQKFAHHIIAGRLMVIHAPEEYYPVLNGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCANISDYYVMLEDDVRCSKNFLTAIKKVITSLQGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEELIDLPDNPPASLYTNMSVFENYDASKAYSSVDGYFWGKPPSTGDVFVVVFENPVIIKKIKVSTGTEDRQNDILHHGALDVGGYIRYFKQNRQCITYIRLGEFKNGNFEVSDVNQKIPFDVHCMRIHVTKTQKEWLIIRSISIWTS
What is the function of this protein?
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans.  Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans.  Essential for the production of tri- and tetra-antennary N-linked sugar chains.  Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity) (By similarity).
What are the official names of this protein?
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc, GnT-IVc, N-acetylglucosaminyltransferase IVc, UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: OSTP_HUMAN
Sequence: MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
What is the function of this protein?
Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
What are the official names of this protein?
Osteopontin, Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1, SPP-1, Urinary stone protein, Uropontin.
What is the protein family that this protein belongs to?
Belongs to the osteopontin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPMI_WOLPM
Sequence: MNIKSVVLCILDGWGNGIENNKYNAISNANPPCWQYISSNYPKCSLSACGADVGLPGGQIGNSEVGHMNIGSGRVVIQSLQRINQEIGTIENNVNLQSFINDLKSKNGVCHIMGLVSDGGVHSHQKHISTLANKISQHGIKVVIHAFLDGRDTLPNSGKKCIQEFTKSIKGNDTRIATVSGRYYAMDRDNRWKRTIEAYEAIAFAKAPCHDNAVSLIENNYQNNITDEFIRPAVIGDYQGIKPEDGVLLANFRADRMIQLASILLGKTDYAKVAKFSSILSMMKYKEDLKIPYIFPPTSFADTLGQTIEDNKLRQLRIAETEKYAHVTFFFNCGKEEPFSGEERILIPSPKVQTYDLQPEMSAFELTEKLVEKIHSQEFALIVVNYANPDMVGHTGNIKAAEKAVLAVDDCLAKVLNAVKKSSNTALIVTADHGNVECMFDEENNTPHTAHTLNKVPFIVSCDNLKLRDGRLSDIAPTILQLLGIKKPNEMTGSSLISCITLCHSS
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: MURA1_LISIN
Sequence: MEKIIVRGGKQLNGSVKMEGAKNAVLPVIAATLLASKGTSVLKNVPNLSDVFTINEVLKYLNADVSFVNDEVTVDATGEITSDAPFEYVRKMRASIVVMGPLLARTGSARVALPGGCAIGSRPVDLHLKGFEAMGAIVKIENGYIEATAEKLVGAKVYLDFPSVGATQNIMMAATLAEGTTVIENVAREPEIVDLANFLNQMGARVIGAGTEVIRIEGVKELTATEHSIIPDRIEAGTFMIAAAITGGNVLIEDAVPEHISSLIAKLEEMGVQIIEEENGIRVIGPDKLKAVDVKTMPHPGFPTDMQSQMMVIQMLSEGTSIMTETVFENRFMHVEEMRRMNADMKIEGHSVIISGPAKLQGAEVAATDLRAAAALILAGLVADGYTQVTELKYLDRGYNNFHGKLQALGADVERVDDSKIDVTNLASLF
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_ECO81
Sequence: MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREVGEGFGDFTVRAGIIRPVLDPARDLWD
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: RL332_MYCVP
Sequence: MARNEIRPLVKLRSTAGTGYTYITRKNRRNDPDRITLRKYDPVVRRHVDFREER
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TRHBN_MYCBO
Sequence: MGLLSRLRKREPISIYDKIGGHEAIEVVVEDFYVRVLADDQLSAFFSGTNMSRLKGKQVEFFAAALGGPEPYTGAPMKQVHQGRGITMHHFSLVAGHLADALTAAGVPSETITEILGVIAPLAVDVTSGESTTAPV
What is the function of this protein?
Binds oxygen cooperatively with very high affinity (P(50) = 0. 013 mmHg at 20 degrees Celsius) because of a fast combination (25 microM(-1). sec(-1)) and a slow dissociation (0. 2 sec(-1)) rate.
What are the official names of this protein?
Group 1 truncated hemoglobin GlbN, Truncated hemoglobin, trHbN, Hemoglobin-like protein HbN.
What is the protein family that this protein belongs to?
Belongs to the truncated hemoglobin family. Group I subfamily.
Protein: NGF_BOVIN
Sequence: MSMLFYTLITALLIGIQAAPHTESNVPAGHAIPQAHWIKLQHSLDTVLRRAHSAPAGPIAARVAGQTHNITVDPKLFKKRRLRSPRVLFSTQPPPVAADTQDLDFEAGGASSFNRTHRSKRSSSHPVFHRGEFSVCDSISVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDAKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKTGQRA
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity).  The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse.  In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro) (By similarity).  Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI (By similarity).  Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer.  The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Beta-nerve growth factor, Beta-NGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. Endosome lumen. Note=ProNGF is endocytosed after binding to the cell surface receptor formed by SORT1 and NGFR.
Protein: PHT11_ORYSJ
Sequence: MAGGQLNVLSTLDQAKTQWYHFMAIVIAGMGFFTDAYDLFCISLVTKLLGRIYYTDDSKDTPGALPPNVSAAVTGVALCGTLAGQLFFGWLGDKLGRKSVYGFTLILMVVCSVASGLSFGSSAKGVVSTLCFFRFWLGFGIGGDYPLSATIMSEYANKRTRGAFIAAVFAMQGFGILFGAIVALAVSAGFRHAYPAPSYSDNHAASLVPQADYVWRIILMFGTVPAALTYYWRMKMPETARYTALIARNAKQAAADMSKVLHTQIEESADRAETVAVGGESWGLFSRQFLRRHGLHLLATTSTWFLLDIAFYSQNLFQKDIFSKVGWIPPAKTMNALEELYRIARAQALIALCGTIPGYWFTVAFIEIMGRFWIQIMGFAMMTAFMLGLAIPYHHWTTPGHHTGFIVMYGFTFFFANFGPNSTTFIVPAEIYPARLRSTCHGISAAAGKAGAIIGAFGFLYAAQDQHKPEPGYPRGIGIKNALFVLAGTNFLGTIMTLLVPESKGMSLEVISQEVADGDDEEAAYPK
What is the function of this protein?
High-affinity transporter for external inorganic phosphate (By similarity).  Required for phosphate acquisition in plant.
What are the official names of this protein?
Inorganic phosphate transporter 1-1, OsPT1, OsPht1;1, H(+)/Pi cotransporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PROK1_HUMAN
Sequence: MRGATRVSIMLLLVTVSDCAVITGACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEECHPGSHKVPFFRKRKHHTCPCLPNLLCSRFPDGRYRCSMDLKNINF
What is the function of this protein?
Potently contracts gastrointestinal (GI) smooth muscle.  Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands.  Has little or no effect on a variety of other endothelial and non-endothelial cell types.  Induces proliferation and differentiation, but not migration, of enteric neural crest cells.  Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells.  Positively regulates PTGS2 expression and prostaglandin synthesis.  May play a role in placentation.  May play a role in normal and pathological testis angiogenesis.
What are the official names of this protein?
Prokineticin-1, Endocrine-gland-derived vascular endothelial growth factor, EG-VEGF, Mambakine.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTER_RAT
Sequence: MSSLSGKVQTVLGPVEPSQLGRTLTHEHLTMAFDSFYCPPPPCQEAASREPIMMKNLFWIQKNPYSHQENLQLNQEVEAVREELLYFKAKGGGAVVENTTTGLSRDVRTLKWLAEQTGVHIIAGAGFYVDATHSAATRAMSVEQLTDVLISEILHGADGTSIKCGVIGEIGCSWPLTDSERKVLQATAHAQAQLGCPVIIHPGRNPGAPFQIIRVLQEAGADISKTVMSHLDRSIFDKKELLEFAQLGCYLEYDLFGTELLNYQLSPDIDMPDDNKRIRRVRFLVNEGYEDRILMAHDIHTKHRLMKYGGHGYSHILTNVVPKMLLRGLTERVLDKILRENPKQWLTFK
What is the function of this protein?
Binds resiniferotoxin, a vanilloid that desensitizes nociceptive neurons.
What are the official names of this protein?
Phosphotriesterase-related protein, Parathion hydrolase-related protein, Resiniferotoxin-binding phosphotriesterase-related protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
Protein: RL36_SPHAL
Sequence: MKIRNSLKSLKDRHRDNRVIRRRGRTYVINKTNRRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: K1B_BUNGR
Sequence: VCRDWFKETACRHAKSLGNCRTSQKYRANCAKTCELC
What is the function of this protein?
Inhibits voltage-dependent potassium channels of the Kv1 family (Kv1. 1/KCNA1 (Kd=6 nM), Kv1. 2/KCNA2 (Kd=15 nM), Kv1. 3/KCNA3 (Kd=10-39 nM), Kv1. 6/KCNA6, and KCa3. 1/KCNN4 (Kd=172 nM)).
What are the official names of this protein?
Kappa-actitoxin-Bgr1a, Kappa-AITX-Bgr1a, Potassium channel toxin Bgk.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1b subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: SPEB_ECO8A
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.