PharMolix/UniProtQA huggingface dataset:
Protein: RBAK_HUMAN
Sequence: MNTLQGPVSFKDVAVDFTQEEWQQLDPDEKITYRDVMLENYSHLVSVGYDTTKPNVIIKLEQGEEPWIMGGEFPCQHSPEAWRVDDLIERIQENEDKHSRQAACINSKTLTEEKENTFSQIYMETSLVPSSIIAHNCVSCGKNLESISQLISSDGSYARTKPDECNECGKTYHGEKMCEFNQNGDTYSHNEENILQKISILEKPFEYNECMEALDNEAVFIAHKRAYIGEKPYEWNDSGPDFIQMSNFNAYQRSQMEMKPFECSECGKSFCKKSKFIIHQRAHTGEKPYECNVCGKSFSQKGTLTVHRRSHLEEKPYKCNECGKTFCQKLHLTQHLRTHSGEKPYECSECGKTFCQKTHLTLHQRNHSGERPYPCNECGKSFSRKSALSDHQRTHTGEKLYKCNECGKSYYRKSTLITHQRTHTGEKPYQCSECGKFFSRVSYLTIHYRSHLEEKPYECNECGKTFNLNSAFIRHRKVHTEEKSHECSECGKFSQLYLTDHHTAHLEEKPYECNECGKTFLVNSAFDGHQPLPKGEKSYECNVCGKLFNELSYYTEHYRSHSEEKPYGCSECGKTFSHNSSLFRHQRVHTGEKPYECYECGKFFSQKSYLTIHHRIHSGEKPYECSKCGKVFSRMSNLTVHYRSHSGEKPYECNECGKVFSQKSYLTVHYRTHSGEKPYECNECGKKFHHRSAFNSHQRIHRRGNMNVLDVENL
What is the function of this protein?
May repress E2F-dependent transcription.  May promote AR-dependent transcription.
What are the official names of this protein?
RB-associated KRAB zinc finger protein, RB-associated KRAB repressor, hRBaK, Zinc finger protein 769.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COMFB_BACSU
Sequence: MLVNSKEIVMKELLDRYMDQLHMACTCQVCQNDVLALSLNKVSPSYVTDFKKIAYTKAELVDKQKNTAMLVILAESAAVVSESPSDLCQTKQEEAFIN
What are the official names of this protein?
ComF operon protein 2.
Protein: MYD88_CERAT
Sequence: MAAGGPGTEPAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETHADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWTRLAKALSLP
What is the function of this protein?
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.  Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.  Increases IL-8 transcription.  Involved in IL-18-mediated signaling pathway.  Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes.  Upon TLR8 activation by GU-rich single-stranded RNA (GU-rich RNA) derived from viruses, induces IL1B release through NLRP3 inflammasome activation (By similarity).  MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity).
What are the official names of this protein?
Myeloid differentiation primary response protein MyD88.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_PELPD
Sequence: MTQNYVYIETFGCQMNVNDSERILTMLADIGYVPTQEPARARLILLNTCSVRAGAEEKVYRRLENLVVLKRHNSRLIIGVGGCVAQQEGEALLERIPKLDLVFGTHNLHLLNDMVLAAERGERKSETSFIDNDQRLDLFPPIRGTARISSFVTVMQGCENYCSYCIVPYVRGPEVSRRSGDILREVRQLADQGVREVALLGQNVNSYGLKSSAEPSFAELIRLVAAVDGIRRIRFFTSHPKDMSPELIACFGDLPALCSQLHLPAQSGSDNVLARMGRGYTREEYLEKVRALRAVRPDIVFTGDMIVGFPGETEEEFQETLSLMEEVRYIDLFSFAYSPRPGTRAAELADDLSRGEKQSRLERLQALQKRTTMEINDVLLGTRQTVLVEREGKRPGQISGKADNGRTVNFSGDRSLIGTFVDLRIIQVFQNSLLGELLPG
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_SHEON
Sequence: MMTQVPDTPQALYRALPSMDSLLADAVLAPLLQRYGKAAVKAALDSQLRTARELIAQERRLPAWCANPSLLNGYLVDQLSKDYSHSLKPVWNLTGTILHTNLGRAQQSEAAIRAVTSVMRYPTPLEFELAAGERGHRDNAISGLIQRLTGAEACCVVNNNAAAVLLMLSAVAAGKEVIVSRGELVEIGGAFRIPDIMRQAGCTLVEVGSTNRTHLKDYEQAITENTAAIMKVHTSNYHISGFTAAVEEARLGQLCRERGILLISDLGSGSLTDLRRFGLKQEPTPQAMLADGVDLVSFSGDKLLGGPQSGLIVGKQALINKLQSHPLKRALRCDKLILAALEATLIHYLNPETLDKELPIMAKFARSQAELRQIGERLQQALAPLFTPSYGLELVECQTQVGSGSQPDTFLPSIGLCFNAQEGGSLTLLEQHFKQAQRPVIGRMTQDQLRLDLRGIDDEAELLAELSTLGVQL
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_HYDCU
Sequence: MQEVELFTDGGCRGNPGPGGWGALLRFGGVEKELKGAELDTTNNRMELTAAIEGLKALKRPCKVTLTTDSQYVKNGITQWMTNWKKNNWKTAAKKPVKNKDLWQALDEALQPHDVTWAWVKGHSGHDENERVDELANQAMDELTG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS48_CVBEN
Sequence: MPMATTIEGADYTNIMPITVLTTVYLGVSIGIDTSTTGFTCFSWY
What are the official names of this protein?
Non-structural protein of 4.8 kDa, ns4.8, 4.8 kDa accessory protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns4/ns4.8 protein family.
Protein: THPR_THEMA
Sequence: MRTFIAIDVNEEVKKQASEIIEKLMKRGFGATWVSEENMHLTLFFLGEVDEQKISEIAEHLCRRVRGFPSFSFTVKGFGYFKRKMSPRVFWLGVENTDRLMKLYEELRNELSHHGFSFEEKFVPHITIGRVKYYPDKWEKLIEDIDFPPIEVAVDRFKIYSSTLTPTGPIYKVLYECQFEGGLIRYA
What is the function of this protein?
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
What are the official names of this protein?
RNA 2',3'-cyclic phosphodiesterase, RNA 2',3'-CPDase.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. ThpR family.
Protein: GSTUI_ARATH
Sequence: MATEDVKLIGSWASVYVMRARIALHLKSISYEFLQETYGSKSELLLKSNPVHKKMPVLIHADKPVCESNIIVHYIDEAWNSSGPSILPSHPYDRAIARFWAAYIDDQWFISVRSILTAQGDEEKKAAIAQVEERTKLLEKAFNDCSQGKPFFNGDHIGYLDIALGSFLGWWRVVELDANHKFLDETKTPSLVKWAERFCDDPAVKPIMPEITKLAEFARKLFPKRQA
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase U18, AtGSTU18, GST class-tau member 18, Glutathione S-transferase 29.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RF1_PROM5
Sequence: MEYTTLIARLKTASKSFVNLEMQLADPDIANNPKKLELIAKERAKLEPLVLDFNQLLDTDKEIDDSRQLLKDNRNDKDMELLINEELCNLEVLKNSLIQKVTIALLPKDPRDERSVMLEIRAGAGGNEACIWAGDLARMYERYGQKIGWSVKPISASESDMGGFKELVISIKGDSVYSQLKFEAGVHRVQRVPATESQGRVHTSTATVAVMPEADPVEVKIDPSDLEIGTARSGGAGGQNVNKVETAIDLIHKPTGIRVFCTQERSQLQNRERAMEILRAKLYEIQLKEANDKERSQRLMQVGTGDRSEKIRTYNFKDNRTTDHRLGSNFALEPILAGQLDEVIDACIAQEQKRIMEDFNENEN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_BACCN
Sequence: MSRISVENVKHVAHLARLAITDQEAEKFQKQLDAIVTFAEQLNELDTTNVKPTTHVLTMRNVMREDVPEQGLPVEEVLKNAPDHKENQIRVPAVLE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: NHAA_LEGPA
Sequence: MNKSGSFYNLETIGGILLFIAAVIAIIIANSPFRVGYEYFLSINGSVSVGNLSITKPLLLWINDGLMAIYFLLIGLEIKREVNRGILSDKTNLLVPALTALAGLIFPALIFIFFNAHHPVYLKGWAIPTATDIAFTLGIVSLLGSRVPFSLKILLTAIAIFDDIAAIVIIALFYTEQLSLLSLSLALVFTLILIGLNYFKCRRISVFMLFGVALWIAVLKSGVHATLAGIVIAMTIPDEGKESMLARLEDGLHHWVVFLILPLFAFANAGVSFVGLDASMFTHPVVLGIGLGLFLGKQLGIFLSLGYFVQFKKFLKADKVNLAQVYGIALICGVGFTMSLFIGSLAYQNYDLSLMPMVKIGVVLGSFIAGLTGFLVLKLKQQ
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYV_RICCN
Sequence: MKEFPKNYNFTENEKKWQQIWQEKQIYAYNPNAAKEETYVIDTPPPTVSGQLHIGHVYSYTQTDFIVRFQRMMGKNIFYPMGFDDNGLPTERLVEKQKQIKAYNMDRSEFIKICEEVVESEEEKFRSLFNQIALSVDWSLEYQTISPLSRKISQMSFLDLVQKEEIYRTNQPILWDPVDGTALAQADIEDKEKTSFMNYITFKTEQGDPLTIATTRPELLPACVAVFYHPDDGRYKHLAGKSAITPLFNEQVPLLTDPLVRQDKGTGLVMCCTFGDQTDITWWKTHNLPLKTIITKKGTIDFQHETSIDGLKIKEARTKIIDILKEQELLIKQEDITHTVKCAERSGAPLEILTVPQWFVKTISHKEELLKRANELNWHPKHMKIRLENWINAISWDWCISRQRYFGVPFPVWYSKRVGEEGKILYADVTQLPIDPLKDLPMGYSKEEVEPDYDVMDTWATSSVSPQLSTHGISDDFAVNKDRHDKLFPMDLRPQAHEIIRTWAFYTILKAHLHQNTLPWKNIMVSGWCLAEDRSKMSKSKGNVLVPEKLLEQYGSDVIRYWSANSKLGADTAYSEDVMKNGKRLVNKLWNAAKFVFIHFDKLKGEDKKASLLDIKEKITNEFDKWMVNKLVELVKLATNELQNYEYANAMHLTEKFFWVVLCDNYLEISKTRSYDEEHKNPQGQYSSILTLYHVMQTLLKLFAPFMPHITEELYQILYSENSIHVKGSWVNYSDLNYEINAKGAEGLLEILDIVRKFKAEKNLSIKTPIKLLEVSGIVLSAELTEDLKNVTSAEEIQFEMKDDKIKVNIIL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_STAAC
Sequence: MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_PSEP1
Sequence: MAKKIQAYIKLQVKAGQANPSPPVGPALGQHGVNIMEFCKAFNARTQGQEAGLPTPVIITVYSDRSFTFETKSTPASVLLKKAAGLTSGSARPNTVKVGTVTRAQLEDIAKAKQADLTAADLDAAVRTIAGSARSMGLNVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CR3LB_DANRE
Sequence: MDHYSDQGGDGIELLDLLFDKNDGILRYENMGQQNNQLWPVQDPHMMMTPQGNEDFFNALIGGSDSVSGSPVWSPSPSDSGISEDPHSDHIDSPPPNASPPMEPHIVVSQTQHSLNINFPFDFNGWETGFLPDQSGGTQCASETPQAQQTTGFPLTVKDLLLSGTPEPAAKVSQQSYQELILTEDEKRLLAKEGMTLPNQFPLTKYEERILKKIRRKIRNKQSAQESRKKKKEYIDGLESRMAACSAHNHELQRKVFQLEKCNISLMEQLRRLQALVMNGSNKPVQAGTCVLVLLLSFTLILLPNLKPFTDTKVSQHGDFSPMRVQSRSLHNLQSSRVLRNLDHPYSMTENAKILPRFPEDKTMEEIASLLGRLHRRPQFTEYDPESHNHSFDQHDEHHHGDPITGHVATVTLNPRRGSRRSPHADDM
What is the function of this protein?
Transcriptional activator.  Binds the cAMP response element (CRE).  Activates transcription through box-B element and CRE.  Seems to function synergistically with atf6 (By similarity).  Regulates FGF21 transcription (By similarity).
What are the official names of this protein?
Cyclic AMP-responsive element-binding protein 3-like protein 3-B, cAMP-responsive element-binding protein 3-like protein 3-B.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Processed cyclic AMP-responsive element-binding protein 3-like protein 3-B]: Nucleus.
Protein: LSPA_SALHS
Sequence: MSKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGICVILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGNWHFATFNLADSAICIGAALIVLEGFLPKPTAKEQA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2234_ARCFU
Sequence: MERVDELVERECICRDCSTYVAEESKTGFCYFGTSEVIKDEKGCLCPLCKVAAVMELKGEFYCTRGS
What are the official names of this protein?
Uncharacterized protein AF_2234.
Protein: SYL_PYRNV
Sequence: MSELSRFFIELGERWQRRWREARVFEPEPAPGVPKYFITAAYPYPNGAIHIGHGRTYLVADVMARFQRHLGRSVLFPMGFHYTGTPILTIAEVIAAGDKAVMEEYMELYGVPEEEIKKMGDPLYLARYFHGQSKRAMERFGLSIDWTREFTTIDPEYQRFIQWQFEKLRKKGLIVRGRHPVGWCPRHSMPVGAHDTKDDKEPDIGQWTLVYFTDSEGLTFPTATLRPETVLGVTNLWINPDAEYVVAEFDGRRAVVSRDAAYRLSFQVGVKILREARGREFVGRMVQNPVTGEWVPVYEARFVDPKVGTGVVMSVPAHAPYDYAALRDLGTVKLIPLIRVEGYGDYPAKEVVERMGIKSQADPALEDATKEVYSAEYARGVMREDVAERVGAHLEEPARSMLRAVFKMYFAGRPVREAREFIARWLTEARLGGVMYDIMNKPVYCRCGTEIVVKVLEDQWFINYGESRWKEAARELVKEMSIVPGEARAQFLATIDWLDKRACARTRGLGTPLPWSSGWVIESLSDSTIYMAFYTVVKRIRQFGIRPEQLTEEFWDFVFLGQGSADEVSKKTGVPVEALKAIREEFEYWYPLDSRNSGKDLIPNHLTFFIFNHVAIFPREKWPRQIVANGWVLREGEKMSKSKRNVLPLDRAVEMYGPDPLRATLALAAEVEQDLDFRDAEARRNAQQLMSIYTLAQRLVQGAEERPPTWVDQWLVAEISRVLERAREAYEKVRVRQAAVEVLYNAKAVFDQYLAMVEKPSRQAVEAAKAWAVAMEPLVPHLAEELWATLGGAGFAALAPWPKLRAEPAALLAKRYVDMLIEDVKNIPAFGQGAKRVVIYVNRSFAWVKAALAGDVKTVIGAGVPPQQAKKVVDLVKTLGDEMRGLIAAVDHFDELEALRSYRNYVEKALGAPVEIYGADDPAAPDLGGKKRVALPLKPGIYVEK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHLB_AERS4
Sequence: MSKTHLTTEKFAQMGLEPEVLAGLESKGFHYCTPIQALSLPLLVEGHDLAGQAQTGTGKTIAFLAATFNYLLTHPLSNPRLVNQPRAIIMAPTRELAVQIYNDADTISASTGLKLGLAYGGEGYDKQLAVLEQGVDILIGTTGRIIDYFKSKVIDLSNIQVVVLDEADRMFDLGFIKDIRFLFRRMPAPTERLSMLFSATLSLRVQELAYEHMNHPEHVQIEPEQMTGIRIQEELFYPSNEDKMLLLLSLMEEEWPEKAIVFANTKHVCEDVHAWLENDGHRVGLLTGDVPQKKRMKILEDFTKGTLDILVATDVAARGLHIPDVTHVFNYDLPDDAEDYVHRIGRTGRAGKSGHSISLACEDYAFNLPAIEEYIHHPIPVSKYDREALLDDVTAPKRVVRNRQPVNRNMRDRQGGGNSNNRRRPPRKS
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AL3B1_HUMAN
Sequence: MDPLGDTLRRLREAFHAGRTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLRAWMKDERVPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQYVDQSCFAVVLGGPQETGQLLEHRFDYIFFTGSPRVGKIVMTAAAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGRVAIGGQSDESDRYIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGFCGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSPGMEKLNALRYPPQSPRRLRMLLVAMEAQGCSCTLL
What is the function of this protein?
Oxidizes medium and long chain saturated and unsaturated aldehydes (PubMed:17382292, PubMed:23721920).  Metabolizes also benzaldehyde (PubMed:17382292).  Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde (PubMed:17382292, PubMed:23721920).  May not metabolize short chain aldehydes.  Can use both NADP(+) and NAD(+) as electron acceptor (PubMed:17382292).  May have a protective role against the cytotoxicity induced by lipid peroxidation (PubMed:17382292).
What are the official names of this protein?
Aldehyde dehydrogenase family 3 member B1, Aldehyde dehydrogenase 7.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.
Protein: NADA_PSET1
Sequence: MSLAQTIMPEGYIFPPKPVPLTQNEQGEYKARIKQLLQEKNAVLVAHYYTDPEIQALAEETGGCVADSLEMARFGTRHDADMIIVAGVRFMGETAKILTPNKTVVMPTLEATCSLDIGCPVDEFSAFCDQHPDRTVVVYANTSTAVKARADWIVTSSCALEIVEHLDELGEKIIWGPDKHLGSYIQKNTGADMIMWNGACIVHDEFKTKALKDMKALHPDAGVLVHPESPEEIVALADAVGSTSQLIKAAQTMSNKKFIVATDRGIFYKMQQLCPDKEFFAAPTAGEGASCKTCAHCPWMAMNGLKAIEEALIDPKGKEVFVDMDLREGALKSLNRMLDFTATMAK
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4RJ_SINFN
Sequence: MLAANERPEAPTAIRIDLGAIFVSLELSRSKWLITSLSPGGGEKMSKHAVAADDIAGLLARFAELKRKARARTGRYFPTIVIQEAGLDGFWIHRVLQAEGIESHVVDPAPIPTSRRRRRAKTDKIDGETLVRALLAYKRGEPRVCAMLRVPTPEEEDRRRISRERKALTNERVRHVNRIKGLLFSQGVSGYQPLRRDRRTRLEELRTGDGRPLPTHLKAQVGRELDRLELLIGQIKAVEVERDAMLAAAPVGSAHFADCEQPAPAMLLALKGIGPEFAAVLWSEGLSRHFDNRRQVAAYAGLAPTPWQSGSVDHDQGVSKAGNPRLRTTLIQGAWLWLRHQPHSALSLWFKQRGKQNDGRLKKKKTIVALACKLLVALWKYVNAGVVIEGAVMKTP
What are the official names of this protein?
Putative transposase y4rJ.
What is the protein family that this protein belongs to?
Belongs to the transposase 20 family.
Protein: FTSH_NATTJ
Sequence: MNRFTRQAVLYLLILMIVVGIFQQLNQEPEAEEDLFYNEFLNKVEAGEVDRVDITERDIEGELTDGTSFVTRDPGDPELIETLKEYEVNIKDHEVPGPPWWASLFTYIIPFVLLIAIFFFFMQQSQGGGGRMMNFGKSKAKLHEGDQKSNVKFHDVAGADEEKEELVEVVNFLKEPQKFIDLGARIPKGVLLVGPPGTGKTLLGRAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFENAKKNSPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDVNEGIIVMAATNRSDILDPALQRPGRFDRQITVNAPDLKGREEILKVHARDKPLEDNVDLKVVARRTPGFTGADLENLVNEAAIYAARRNKNRIGMKELEGAIDRVIAGTEKKSRVISEFEKKIVAYHEAGHAIVGYLLPHTDPVHKVSIIPRGAAGGFTLMLPEEDRQFMTKTELLERVSTLLGGRVAEELKLKEISTGAQNDLERATTIVRQMIMEYGMSENLGPITLGQKQGQVFLGRDIARDKDYSENIAYAIDKEIRNMVDSSYQEARETLEENIDKLEKIAQALMERETLVAKEIKMLMEGKDLPPIEESEDTETLDFLVDEQQDTKSESDNEQQSQENQADNNQNDSTTEFDDEQQTNDDNRPEDDEDNEEDKNKGNNDFNLKIDYNKEDKDNKDKDK
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: RS16_STAAC
Sequence: MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: LIPR_MYCTO
Sequence: MNLRKNVIRSVLRGARPLFASRRLGIAGRRVLLATLTAGARAPKGTRFQRVSIAGVPVQRVQPPHAATSGTLIYLHGGAYALGSARGYRGLAAQLAAAAGMTALVPDYTRAPHAHYPVALEEMAAVYTRLLDDGLDPKTTVIAGDSAGGGLTLALAMALRDRGIQAPAALGLICPWADLAVDIEATRPALRDPLILPSMCTEWAPRYVGSSDPRLPGISPVYGDMSGLPPIVMQTAGDDPICVDADKIETACAASKTSIEHRRFAGMWHDFHLQVSLLPEARDAIADLGARLRGHLHQSQGQPRGVVK
What is the function of this protein?
Required for maintaining the appropriate mycolic acid composition and permeability of the envelope on its exposure to acidic pH.
What are the official names of this protein?
Putative acetyl-hydrolase LipR.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: PANB_TOLAT
Sequence: MSKISLTQVQKMKQSGEKIAMITAYDATFARLFDDEGVHSILVGDSLGMVVQGHNDTLPVTVNDMVYHTANVARGVQNALLIADLPFMSYSDVHSACINAGRLMAAGAKMVKIEGGDWLCDTVKQLNRNGIPVCAHLGLTPQSVHLFGGFRIQGRDAQRAEEIYHHALALQTAGVQMVVLECVPEQLAERITKALRIPVIGIGAGAQTDGQVLVMQDALGVTTGYIPKFSKNFLAETGDVRKAIQLYVEQVANGQFPAAEHTFN
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_SYNP6
Sequence: MIQQETYLNVADNSGARKLMCIRVLGSNRRYAGVGDVIIAVVKDALPNMPVKKSDVVRAVVVRTKKSLRRDSGNVIRFDDNAAVIINADGNPRGTRVFGPVARELRDRNFTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: EFP_RHORT
Sequence: MKMQANQIRPGQVLEHQGKRWTVLKIQLIQPGKGGAFIAVEMRDVDSGNKTNERWRTADTVERLEVREIDCQYLFKDDTGYTFMDKETFEQFSMAADALGEQAGFLQESMEVTVDCIEGSPVSVNLPSQVILQVVEADAVVKGQTASSSYKPGLLENGMKVMIPPFIEAGTRIVVSTVDCSYIERAK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.