PharMolix/UniProtQA huggingface dataset:
Protein: CLCB_DICDI
Sequence: MSNNYKAGTAINGNDYLLLNIDGNKDCDTDNGFFSGKNFFGGNQTSITHRRHHKMTTKTDRELMSHFESLDFNAIDNIIHRKYTFEKKKYQKILKTLGKWVICTLIGVVVGLVCYCLKESVDQLQSLKLTQVKKFYSTESTIFIPFLVYLGFNLCYGLISGLLVCIFGPMSSSSGLPEVKGYLNGIRISKAFNLKTVLGKLVSLIFSFSSGLVLGPEGPMFHIGAGIGSSMSQFKSKTLKFHLKSFWIFQNDSDKRDFISCGAAAGIAAAFGAPIGGVLFCLEEGSSFWSRQLTWRTFFSCLIATMTANLFLQGFTQQIHDYGVLTFGVSKSYLYTYTELIPFMIMGIIGGLLGAIFVHVNVRVNHWRKKLFANKSKLYKMIEVCVIVILSSVVCFFPALLADCRPISGISGLTPGTCDPGDDSTLILNQFNCAEGYYNPMATLTLTTLENSLQIVFSRSTNIFTAQTLLTFSIFYYVLTIITSGLYVASGIFIPMMLIGSSWGRLIGIFLSKYFTSIDPSIYALIGAASMMAGSLRMTISLVVIIVELTETTQYLLPVILSVMVGKWCGDIFNESIYEHLIELKHIPYLNSQPPNHLRKKTVAEAMSTDVKTLPEIVKVKTALTILETCPHNGFPVVMLPQLHSNSNLNDSNQLSLSLNLNNNNNNNNNNNNNNNNNNNNNNNNNNNNILCGLILRSQLSVLLRRKIFNSPEDLKNIDFISDKGYNLPIDHTEFSQELASKIPPIHELSKLITKEDLDMYIDLRPYMNFAVVSIKNYSSLSEAYQIFRQVGLRHMVVINVFNNVVGMLTRKDLC
What is the function of this protein?
Voltage-gated chloride channel.  Chloride channels may have several functions including the regulation of cell volume, membrane potential stabilization and signal transduction (By similarity).
What are the official names of this protein?
Chloride channel protein B.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KNG1_MOUSE
Sequence: MKLITTLLLCSGLLLTLTQGEEAQEIDCNDEAVFQAVDFSLKQFNPGVKSGNQYMLHRVIEGTKTDGSPTFYSFKYLIKEGNCSAQSGLAWQDCDFKDAEEAATGECTATVGKRENEFFIVTQTCKIAPSKAPILKAYFPCIGCVHAISTDSPDLEPVLKHSIEHFNNNTDHSHLFTLRKVKSAHRQVVAGLNFDITYTIVQTNCSKERFPSLHGDCVALPNGDDGECRGNLFMDINNKIANFSQSCTLYSGDDLVEALPKPCPGCPRDIPVDSPELKEVLGHSIAQLNAENDHPFYYKIDTVKKATSQVVAGTKYVIEFIARETKCSKESNTELAEDCEIKHLGQSLDCNANVYMRPWENKVVPTVKCQALDMTEMARRPPGFSPFRSVTVQETKEGRTVSPPYIAREQEERDAETEQGPTHGHGWLHEKQIKANKNHRGHKHGHDHGHWSPRRHGLGHGHQKPHGLGHGHQLKLDYLRHQREDGDDHTHTVGHGHGHGHGHGHGHGHGHGHGHGHGHGHGHGKHTNKDKNSVKQTTQRTESLASSSEYSTTSTQMQGRTEGPTLTPPRAQPTVTSSGFQDSDFIEDVVATTPPYDTGAHDDLIPDIHVQPDSLSFKLISDFPEATSPKCPGRPWKPASWEDPNTETTEFSDFDLLDALS
What is the function of this protein?
The active peptide bradykinin is a potent vasodilatator that is released from HMW-kininogen shows a variety of physiological effects: (A) influence in smooth muscle contraction, (B) induction of hypotension, (C) natriuresis and diuresis, (D) decrease in blood glucose level, (E) it is a mediator of inflammation and causes (E1) increase in vascular permeability, (E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e. g.  prostaglandins), (F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action).
What are the official names of this protein?
Kininogen-1.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: Y665_HAEIN
Sequence: MNFCRILLKPLKKNEALSGYSAEGLHYLTDNKHFNPELPFSRQEFITVKPQKQQGMSISGFQPKLQLIIKDEHFDSVNQQGNYILKPSPEEYPFLAENEHATMRIMKELGFDVPENGLVSFAGEQNHKEFAFVITRFDRDKQQKPMHQEQLDGAMNIRDKYGKIGADNEQYVSYEQIAKFILQHTENHLAQQREIFRRIIYAYLLGNNDLHLRNFSFIYPKNSHPKLAPIYDFVSVSPYPEIFNSTLLALPLLAREEGNATLAKGFNTQYGEYIGDDFVEFGENIGLNKNVIIQKLIPEIIQEKEKVEQIYSQSFMPQPHIDCVLKTYRKRLALLNLLNEPEL
What are the official names of this protein?
Putative kinase HI_0665.
What is the protein family that this protein belongs to?
Belongs to the HipA Ser/Thr kinase family.
Protein: RDGC_SODGM
Sequence: MLWFKNVMIYRLNRPIELSVEQIEQQLSAFAFTPCGSQDMAKSGWVPPMGAKSDALTHSIPGHVLLCLRKEEKILPSSVVKQELEGKISKLENDQSRKLRKTDKDALKDELLHQLMPRAFSRFGQTLLWLDLANDLVLVDAGSARKAEDCLAMLRKSIGSLPVVPLTMEKPIEMTLTEWVRSGEPAAGFAIQDEAELKVLLEEGGILRCKKQDLSSDEIAVHIEAGKLVTKLALDWRERVQFLLGDDGTVKRLKFSDTLREQNDDIDREDFAARFDADFLLMTGELTGLIAELIAGLGGEAPRQG
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ARNF_PSEU2
Sequence: MTHRRATLCAMASVALVSAAQLGMRWSMSRLPSPVQWLEMQEHAQLDLSALRVVCASITAYALSMLFWLLALRVLPLSRAYSLLSISYALVYTLAATLPFFHETFTVSKTVGVSLIVAGVLTINLRRLPRPSPQDLSHENQRFR
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LFTR_RHOPB
Sequence: MTGRDSASSDITPEVLLRAYACGIFPMAESVDDPTLFWVEPERRGIIPLDGFKVASRLARTVRSDVFTVSVDRAFKQVIDGCAAPQPGREDTWINRRIRELYIGLYQLGHCHSVEVWQNDDLVGGLYGVNLGRAFFGESMFHRARDASKVALVHLVARLIEGGFVLLDTQFVTEHLRTFGATEVPRRRYRAMLDVAITGAADFARLPTEQPIAGTRALAIISGREGLGRG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_AQUAE
Sequence: MGFLEEVRSYKESQIDTSPEYLRKLEELIEERKEFYDFEKALTSCGTKIIAEVKKASPSEGNIKEVNPEEQAKLYEKAGAIAISVLTDEKYFKGSLEDLRNVRESVKLPLLRKDFTVHKVQILEAKAYGADIVLLIVRMLSDKELKELLDFSEELGLSPLVEVFTLDEAKRALDAGAKIIGINNRDLETFKVDINKTKELAPKIKDLGAKFVISESGISKREEILELMNYQVDGFLIGTSLMKSENPYRKLKELLGF
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: DUS29_GASAC
Sequence: MSSRVVKSRSKNPYAAVQVDPDSDYITPGTLDLEQLFWTSTGAQYAHVNQVWPSVYVGDEKTALERPGLRVLGITHVLNAAEGKWNNVLTGAHYYTDMDIQYFGVEADDKPTFNISQFFCSATQFIHEALSHPKVLVHCVMGRSRSAALVLAYLMMEHGLTVVDAIEHVRQRRCVLPNHGFLRQLRALDITLQEDRLRQKRGMQEQ
What is the function of this protein?
Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity).  Involved in the modulation of AMPK and MAPK1/2 signaling pathways (By similarity).
What are the official names of this protein?
Dual specificity phosphatase 29, Dual specificity phosphatase DUPD1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CBPA_ECO55
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHSDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GPMA_PROMH
Sequence: MAVTKLVLVRHGESVWNKENRFTGWTDVELSDKGRNEAQEAGKLLKAEGFTFDYAYTSVLKRAIHTLWNILDEVDQQWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDDRFPGKDPRYASLTEAELPLTESLALTIDRVTPYWEEVIKPRVASGDKVIIAAHGNSLRALVKYLDNMSEEEILELNIPTAVPLVYEFDENMKPIKRYYLGNAEEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: Y1999_MYCTU
Sequence: MRRPLDPRDIPDELRRRLGLLDAVVIGLGSMIGAGIFAALAPAAYAAGSGLLLGLAVAAVVAYCNAISSARLAARYPASGGTYVYGRMRLGDFWGYLAGWGFVVGKTASCAAMALTVGFYVWPAQAHAVAVAVVVALTAVNYAGIQKSAWLTRSIVAVVLVVLTAVVVAAYGSGAADPARLDIGVDAHVWGMLQAAGLLFFAFAGYARIATLGEEVRDPARTIPRAIPLALGITLAVYALVAVAVIAVLGPQRLARAAAPLSEAMRVAGVNWLIPVVQIGAAVAALGSLLALILGVSRTTLAMARDRHLPRWLAAVHPRFKVPFRAELVVGAVVAALAATADIRGAIGFSSFGVLVYYAIANASALTLGLDEGRPRRLIPLVGLIGCVVLAFALPLSSVAAGAAVLGVGVAAYGVRRIITRRARQTDSGDTQRSGHPSAT
What is the function of this protein?
Probable amino-acid or metabolite transport protein.
What are the official names of this protein?
Uncharacterized transporter Rv1999c.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OPHN1_MOUSE
Sequence: MGHPPLEFSDCYLDSPDFRQRLKYYEEELERTNKFIKDVIKDGSALISAMRNYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVQNASDLLIKPLETFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLLEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWAKYYCRYEKETRMLTMIPMEQKPGAKQGPVDLTLKYCVRRKTESIDKRFCFDIETNERPGTITLQAPSEANRRLWMEAMDGKEPIYHTPITKQEEMELNEVGFKFVRKCINFIETKGIKTEGLYRTVGSNIQVQKLLYAFFDPKCPGDVDFHNSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEDSQVPPVPPPRVTARRHKPITISKRLLREKTVFYTSSLDENKDESHHQTPNGTITSNLDPPKLLQHLKPPMQKSGETDPGRKSPSRPVSDCQSEPCLETDVGRLLFRLQDGGTKATPKASNGPVPGSGHTKTSSFHIRRPAPRPMAHHKEGDTDGFSKVRPPGEKQTIIRPPVRPPDPPCRSITPQKPEPKPETGSGNADEIPSSVVASRTRFFETASRKTGSSQGKLPGDES
What is the function of this protein?
Stimulates GTP hydrolysis of members of the Rho family.  Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function.  Critical for the stabilization of AMPA receptors at postsynaptic sites.  Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals (By similarity).  Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.
What are the official names of this protein?
Oligophrenin-1.
What are the subcellular locations of this protein?
Postsynapse. Presynapse. Cell projection, axon. Cell projection, dendritic spine. Cell projection, dendrite. Cytoplasm. Note=Present in both presynaptic and postsynaptic sites.
Protein: MSX1_SAIBB
Sequence: MTSLPLGVKVEDSAFGKPAGGGSGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESSLAASESAQAAGGLTQPLGVPPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGSPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
What is the function of this protein?
Acts as a transcriptional repressor.  May play a role in limb-pattern formation.  Acts in cranofacial development and specifically in odontogenesis (By similarity).
What are the official names of this protein?
Homeobox protein MSX-1, Msh homeobox 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTHY_BORPA
Sequence: MTPRGRFITLEGVDGAGKSTHTAWMVQALRDLGLTVLATREPGGTPVGEKLRELLLSEPMALETETLLMFAARCEHVREVIAPALARGEWVVCDRFTDASYAYQGGGRQLGAARVAALEQWVHPDLQPDRTWLFDVPLDVARARLARSRQLDRFEREEDAFFERTRAAYHERARSSDGRIRIIDSSRPLEVVRAQLDSEVRELVAQAA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SNX13_MOUSE
Sequence: MLTEASLSIWGWGSLGIVLFLITFGPFVIFYLAFYILCFVGGGLVVTLLYGKTNSEKYLEQCEHSFLPPTSSGVPKCLEEMKREARTIKIDRRLTGANIIDEPLQQVIQFSLRDYVQYWYYTLSDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQRVTEKDDQVKGTAEDLVETFFEVEVEMEKDVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGDFQSKIMRYFVREILARGILLPLINQLSDPDYINQYVIWMIRDSNCNYEAFMNIIKLSDNIGELEAVRDKAAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGKEINTVKLAANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYRVTAQQQLEVLSGRQRDGKQQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPEIFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDMLKDPSFRGSDDGDGESFNGSPTGSINLSLDDLSSVTSDDSVQLHAYISDTGVCNDHGKTYALYAITVHRRNLNTEEMWKTYRRYSDFHDFHMRITEQFENLSSILKLPGKKTFNNMDRDFLEKRKKDLNAYLQLLLTPEMMKASPALAHCVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGVTKMSDNVGRMSERLGQDIKQSFFKVPPLITKTDSDPEHCRVSAQLDDNVDDNIPLRVMLLLMDEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDHVDWMTSPEQVADSVKRFRDAFWPNGILAETVPCRDKAIRMRTRIAGKTKLFAIMPDELKHIIGAETTRKGILRVFEMFQHNQLNRRMVYVFLEGFLETLFPQYKFRELFNKLHSRSKQMQKYKQKLQSTQAPSLQKR
What is the function of this protein?
May be involved in several stages of intracellular trafficking.  Acts as a GAP for Galphas (By similarity).  May play a role in endosome homeostasis.
What are the official names of this protein?
Sorting nexin-13.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VLN3_ORYSJ
Sequence: MAVSMREVDAVFQGAGQKDGLEIWRIEKLQAVPVPKESHGRFFTGDSYVILKTTALKNGSFRHDIHYWLGKDTSQDEAGTAAIKTVELDAALGGRAVQYREVQGNETERFLSYFKPCIIPEEGGIASGFRHTEINEREHVTRLFVCRGKHTVHVKEVPFARSSLNHDDIFILDTKSKIFQFNGSNSSIQERAKALEVVQYLKDSNHEGKCDVGSVEDGKLMADADAGEFWGLFGGFAPLPRKTFSDLNGKDSAFSSKLICLNKGQTVPVDFDVLTRELLDSTKCYLLDCGSEIYVWMGRETPLEERKRAGSAAEELLREVNRPKSHIVRLMEGFETVIFRSKFSKWPKKADAVVSDESRGKVAALLKRQGFNVKGLAKAAPVKEEPQPQIDCTGNLQVWRVNGTEKTFLSFSEQCKFYSGDCYIFQYSYPGEEGEECLIGTWFGKKSVQDEKTTAISVASKMVESLKFQAVMVRLYEGKEPAEFFSIFQNLVIFKGGVSTGYKKFVSENGIEDDTYSENGVALFRVQGSGPENMQAIQVDTAATSLNSSYCYVLHDGDTLFTWIGNLSSSMDQELAERQLDVIKPNLQSRMLKEGSEYDQFWKLLGVKSEYPSQKIAKDQESDPHLFSCTFSKGVLKVREIFNFTQDDLMTEDVFILDCHSCVFVWVGQRVDTKMRAQALSVGEKFLELDILMENSSQETPVYVITEGSEPQFFTRFFTWDSAKSAMHGNSFERRLSIVKDGVKPKLDKPKRRPTTSSSHTGRSSVPEKSQRSRSMSFSPDRVRVRGRSPAFNALAANFENPNARNLSTPPPAIRKPSPKSPSSDPTKPPQRAASIAAISASFERPRPTLIPKSIKASPDVNKPQVEASKPKPEANGKDSTPSKDSPTVTPTIQEDLKEGQPENEEGLPVYPYERLRTSSINPVTDIDVTKRETYLSAAEFRERFGMTKEAFAKLPKWKQNRLKIALQLF
What is the function of this protein?
Ca(2+)-regulated actin-binding protein.  Binds actin microfilaments (MFs).  Involved in actin filament bundling, severing and capping.  Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner.  MF severing is promoted by VLN1.
What are the official names of this protein?
Villin-3.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: L_SENDZ
Sequence: MDGQESSQNPSDILYPECHLNSPIVRGKIAQLHVLLDVNQPYRLKDDSIINITKHKIRNGGLSPRQIKIRSLGKALQRTIKDLDRYTFEPYPTYSQELLRLDIPEICDKIRSVFAVSDRLTRELSSGFQDLWLNIFKQLGNIEGREGYDPLQDIGTIPEITDKYSRNRWYRPFLTWFSIKYDMRWMQKTRPGGPLDTSNSHNLLECKSYTLVTYGDLVMILNKLTLTGYILTPELVLMYCDVVEGRWNMSAAGHLDKKSIGITSKGEELWELVDSLFSSLGEEIYNVIALLEPLSLALIQLNDPVIPLRGAFMRHVLTELQTVLTSRDVYTDAEADTIVESLLAIFHGTSIDEKAEIFSFFRTFGHPSLEAVTAADKVRAHMYAQKAIKLKTLYECHAVFCTIIINGYRERHGGQWPPCDFPDHVCLELRNAQGSNTAISYECAVDNYTSFIGFKFRKFIEPQLDEDLTIYMKDKALSPRKEAWDSVYPDSNLYYKAPESEETRRLIEVFINDENFNPEEIINYVESGDWLKDEEFNISYSLKEKEIKQEGRLFAKMTYKMRAVQVLAETLLAKGIGELFRENGMVKGEIDLLKRLTTLSVSGVPRTDSVYNNSKSSEKRNEGMENKNSGGYWDEKKRSRHEFKATDSSTDGYETLSCFLTTDLKKYCLNWRFESTALFGQRCNEIFGFKTFFNWMHPVLERCTIYVGDPYCPVADRMHRQLQDHADSGIFIHNPRGGIEGYCQKLWTLISISAIHLAAVRVGVRVSAMVQGDNQAIAVTSRVPVAQTYKQKKNHVYEEITKYFGALRHVMFDVGHELKLNETIISSKMFVYSKRIYYDGKILPQCLKALTKCVFWSETLVDENRSACSNISTSIAKAIENGYSPILGYCIALYKTCQQVCISLGMTINPTISPTVRDQYFKGKNWLRCAVLIPANVGGFNYMSTSRCFVRNIGDPAVAALADLKRFIRADLLDKQVLYRVMNQEPGDSSFLDWASDPYSCNLPHSQSITTIIKNITARSVLQESPNPLLSGLFTETSGEEDLNLASFLMDRKVILPRVAHEILGNSLTGVREAIAGMLDTTKSLVRASVRKGGLSYGILRRLVNYDLLQYETLTRTLRKPVKDNIEYEYMCSVELAVGLRQKMWIHLTYGRPIHGLETPDPLELLRGIFIEGSEVCKLCRSEGADPIYTWFYLPDNIDLDTLTNGCPAIRIPYFGSATDERSEAQLGYVRNLSKPAKAAIRIAMVYTWAYGTDEISWMEAALIAQTRANLSLENLKLLTPVSTSTNLSHRLKDTATQMKFSSATLVRASRFITISNDNMALKEAGESKDTNLVYQQIMLTGLSLFEFNMRYKKGSLGKPLILHLHLNNGCCIMESPQEANIPPRSTLDLEITQENNKLIYDPDPLKDVDLELFSKVRDVVHTVDMTYWSDDEVIRATSICTAMTIADTMSQLDRDNLKEMIALVNDDDVNSLITEFMVIDVPLFCSTFGGILVNQFAYSLYGLNIRGREEIWGHVVRILKDTSHAVLKVLSNALSHPKIFKRFWNAGVVEPVYGPNLSNQDKILLALSVCEYSVDLFMHDWQGGVPLEIFICDNDPDVADMRRSSFLARHLAYLCSLAEISRDGPRLESMNSLERLESLKSYLELTFLDDPVLRYSQLTGLVIKVFPSTLTYIRKSSIKVLRTRGIGVPEVLEDWDPEADNALLDGIAAEIQQNIPLGHQTRAPFWGLRVSKSQVLRLRGYKEITRGEIGRSGVGLTLPFDGRYLSHQLRLFGINSTSCLKALELTYLLSPLVDKDKDRLYLGEGAGAMLSCYDATLGPCINYYNSGVYSCDVNGQRELNIYPAEVALVGKKLNNVTSLGQRVKVLFNGNPGSTWIGNDECEALIWNELQNSSIGLVHCDMEGGDHKDDQVVLHEHYSVIRIAYLVGDRDVVLISKIAPRLGTDWTRQLSLYLRYWDEVNLIVLKTSNPASTEMYLLSRHPKSDIIEDSKTVLASLLPLSKEDSIKIEKWILIEKAKAHEWVTRELREGSSSSGMLRPYHQALQTFGFEPNLYKLSRDFLSTMNIADTHNCMIAFNRVLKDTIFEWARITESDKRLKLTGKYDLYPVRDSGKLKTISRRLVLSWISLSMSTRLVTGSFPDQKFEARLQLGIVSLSSREIRNLRVITKTLLDRFEDIIHSITYRFLTKEIKILMKILGAVKMFGARQNEYTTVIDDGSLGDIEPYDSS
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the paramyxovirus L protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: PAM74_ARATH
Sequence: MDSPCWLLLLLLGAFAIIGCVQAQDQQEFISLDCGLPMTEPSSYTESVTGLRFSSDAEFIQTGESGKIQASMENDYLKPYTRLRYFPEERRNCYSLSVDKNRKYLIRARFIYGNYDGRNSNPIFELHLGPNLWATIDLQKFVNGTMEEILHTPTSNSLNVCLVKTGTTTPLISALELRPLGNNSYLTDGSLNLFVRIYLNKTDGFLRYPDDIYDRRWHNYFMVDDWTQIFTTLEVTNDNNYEPPKKALAAAATPSNASAPLTISWPPDNPGDQYYLYSHFSEIQDLQTNDTREFDILWDGAVVEEGFIPPKLGVTTIHNLSPVTCKGENCIYQLIKTSRSTLPSLLNALEIYTVIQFPRSETNENDVVAVKNIEAAYKLSRIRWQGDPCVPQKYAWDGLNCSNNTDVSKPPRVLSLNLSSSGLTGIIAAAIQNLTHLEKLDLSNNTLTGVVPEFLAQMKSLVIINLSGNNLSGPLPQGLRREGLELLVQGNPRLCLSGSCTEKNSKKKFPVVIVASVASVAIIVAVLVIIFVLSKKKSSTVGALQPPLSMPMVHDNSPEPSIETKKRRFTYSEVIKMTNNFQRVVGEGGFGVVCHGTINGSEQVAVKVLSQSSSQGYKHFKAEVDLLLRVHHTNLVSLVGYCDERDHLALIYEFLPKGDLRQHLSGKSGGSFINWGNRLRIALEAALGLEYLHSGCTPPIVHRDIKTTNILLDEQLKAKLADFGLSRSFPIGGETHISTVVAGTPGYLDPEYYQTTRLGEKSDVYSFGIVLLEIITNQPVIDQSRSKSHISQWVGFELTRGDITKIMDPNLNGDYESRSVWRVLELAMSCANPSSVNRPNMSQVANELKECLVSENLRENMNMDSQNSLKVSMSFDTELFPRAR
What is the function of this protein?
Required for accurate photosynthesis.
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase PAM74, Protein PHOTOSYNTHESIS AFFECTED MUTANT 74.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DEOD_ACTP7
Sequence: MATPHINAPEGAFADVVLMPGDPLRAKYIAETFLEDAVQVTDVRNMFGYTGTYKGRRISVMGHGMGIPSCSIYAKELITEYGVKKIIRVGSCGAVRQDVKVRDVIIGSGACTDSKVNRIRFRDNDFAAISDFDMTLAAVQAAKQKGIAARVGNLFSADLFYTPDVEMFDVMEKYGILGVEMEAAGIYAVAAEYGAKALAICTVSDHIRTGEQTSSEERQLTFNDMITIALESVLIGDKAE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: LPXA_ALLVD
Sequence: MRIHPTAIVEDGAQLHDSVTVGPYSIIESGAVIGEGCRIESNVRIFGVTRMGAHNRVCHGATLGSEPQDLSFTPEKARPLIIGDHNHFKECVNISGGIKSEGGTRIGSHNYWMAFSHAGHDCVVGDHNVFANTATLAGHVEIDDHCFLSGQVAVHQFCRIGSYVMIAGVTGVPQDVPPYMLADGHRARLIGLNVVGLRRNGFGQEQRTRIKQVYRLILRSGLRLDDALQRAEDEYPGPETKRIVAFIRASRRGIVSFG
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMA21_CHICK
Sequence: MERYDKATLNAAFAPEFRQNEGSLTSTLRTLLFFTALMITLPVGLYFSSKAYIFEGTLGMSNRDSYFYAAIVAVVTVHVVLAMFVYVAWSEGTRQWREGKQD
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein VMA21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: IHFB_YERE8
Sequence: MTKSELIERLAGQQSHVPTKVVEDAVKEMLEHMAGTLAEGERIEIRGFGSFSLHYRAPRVGRNPKTGAKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: Y095_MYCTU
Sequence: MLANSREELVEVFDALDADLDRLDEVSFEVLSTPERLRSLERLECLARRLPAAQHTLINQLDTQASEEELGGTLCCALANRLRITKPEAGRRSAEAKP
What are the official names of this protein?
Putative uncharacterized protein Rv0095c.
What is the protein family that this protein belongs to?
Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
Protein: NADK_TROW8
Sequence: MRVYIAHNGCLEAEPIYGTICELVAQRKMSVITDPHARNNESARNTDSGVVSLNQAGRNKYLDQETTSPATSRSINVPFCAGISIGGDGTFLRMARDLKNTGTPLFGVNMGRMGFLVDIEPEDIVNLVENIVKGEYTEEKRLPITASVQRGGKKIHDEWAVNEITIERKVEGKVVDIEVFVDGCRVMDISCNGIIIATATGSTAYSFSSGGPIVWPEMKVTLVVPVSPHELFAKPIVLPDNRSILLKVTSRDNKVVLCSDGQVRLCLQSGDEIACHVGKVPVVFGRVKKGCFAEHLVKKFNLQTA
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.