PharMolix/UniProtQA huggingface dataset:
Protein: ISPH_COLP3
Sequence: MEIILANPRGFCAGVDRAISIVERALDLFGAPIYVRHEVVHNKFVVDGLKDRGAIFVDELDEVPDDNTVIFSAHGVSKAVRQEAKTRALKVFDATCPLVTKVHMEVSRVSRKDIECILIGHAGHPEVEGTMGQYSSDSAGIYLVESPEDVASLVVKNPEKLYFCSQTTLSVDDTMDVIAALQAKFPLIEGPRKDDICYATQNRQDAVREIADKVDLMLVVGAKNSSNSNRLKELASKMGVTSYLIDTAENIETDWLTGVNKVGVTAGASAPAVLIKQVVEALKSYGGHQVIEHPGKEESIVFAVPAELR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RL31B_LISW6
Sequence: MKTGIHPEYRQVVFVDTSTDFKFLSGSTKSSSETIKWEDGNEYPLLRVEISSDSHPFYTGKQKHATADGRVDRFNKKYGLKDANAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: SLX4_YEAS6
Sequence: MELQRAQRNLKFLQNEDYVNVTDQTNLNGESQNAYSLGMETQVPEMQFSLSSDDDSIGTQVKSVTAQKSPMTQETTKNDTERNKDVDKSCNPVSTSHPDLGGSNIEENIFINTQIQSRLDDAEEETNLKLKLEKFKYSFKSSNADDTHSNANVTAKRRPAIRKANSKLKTKPKTKRDPKIIKNITDFNINNYERSRTASLLKQLSGKHKKVLDIIKTQNEGNSDKPPRARNNKGEKATFDTYSEQEWKDIMKLLLQKFPQSEETDLNEVQKFLYGSEKSSNSLDNQESSQQRLWTASQLPPELPDEAIQPEQEERIRDTQSAVNFLSLSQVMDDKSEIMKDEESIIISRGDSTSSQEYGNGLEPQQPVGNVVGEDIELAVGTRINAFSLTDYKACKPMSVEVSRRCENSTDNDYDNISIVSDTTDETSTLFPLDQYRYVFIENDERPPLATDTIGSTQFFTPNTSPLDGIIDLTQESFKAVRSLISPLKVENNKTGVTSQASNQVQVPATRTPTIIPQKNLTTTLKTEEEKNNIGSSIRVKLLQESVVKLNPKLVKHNFYRVEANDSEEEETEFDDQFCIADIQLVDSSKISTKDSTQNPTTSNDIIDTSAASSIASPEKFCEIMMSQSMKELRQSLKTVGLKPMRTKVEIIQSLQTASQILSTANPDNKGEHGGVANFSKIEIFDHLTELIEAFPDFLERIYTFEPIPLNELIEKLFSAEPFVSQIDEMTIREWADVQGICLRNDKK
What is the function of this protein?
Regulatory subunit that interacts with and increases the activity of different structure-specific endonucleases.  Has several distinct roles in protecting genome stability by resolving diverse forms of deleterious DNA structures.  Component of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.  Has a preference for simple Y, 5'-flap and replication fork-like structures.  It cleaves the strand bearing the 5'-non-homologous arm at the branch site junction and generates ligatable, nicked products from the 5'-flap or replication fork substrates.  Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks.  Has Holliday junction resolvase activity in vitro.  Interacts with the structure-specific RAD1-RAD10 endonuclease and promotes RAD1-RAD10-dependent 3'-non-homologous tail removal (NHTR) during repair of double-strand breaks by single-strand annealing.  SLX4 also promotes recovery from DNA-alkylation-induced replisome stalling during DNA replication by facilitating the error-free mode of lesion bypass.  This does not require SLX1 or RAD1-RAD10, but probably RTT107.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HFQ_BRUSU
Sequence: MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CRB12_LITCT
Sequence: MAQINPLPVPLGPWKITVYDQENFQGKRMEFTSSCANIMECGFDNIRSLKVECGAWIGYEHTSFCGQQFVLERGEYPRWDAWSGSNAYHIERLMSFRPICSANHIESKLVIFEKENFVGPQWELCDDYPSLQAMGWGNNEVGSMKVQCGAWVCYQYPGYRGYQYILESDHHGGEYKHWREWGSHAQTFQIQSIRRIQQ
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin A1-2.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: TM115_HUMAN
Sequence: MQRALPGARQHLGAILASASVVVKALCAAVLFLYLLSFAVDTGCLAVTPGYLFPPNFWIWTLATHGLMEQHVWDVAISLTTVVVAGRLLEPLWGALELLIFFSVVNVSVGLLGAFAYLLTYMASFNLVYLFTVRIHGALGFLGGVLVALKQTMGDCVVLRVPQVRVSVMPMLLLALLLLLRLATLLQSPALASYGFGLLSSWVYLRFYQRHSRGRGDMADHFAFATFFPEILQPVVGLLANLVHSLLVKVKICQKTVKRYDVGAPSSITISLPGTDPQDAERRRQLALKALNERLKRVEDQSIWPSMDDDEEESGAKVDSPLPSDKAPTPPGKGAAPESSLITFEAAPPTL
What is the function of this protein?
May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum.  May indirectly play a role in protein glycosylation in the Golgi.
What are the official names of this protein?
Transmembrane protein 115, Placental protein 6, Protein PL6.
What is the protein family that this protein belongs to?
Belongs to the TMEM115 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein.
Protein: LY9_HUMAN
Sequence: MVAPKSHTDDWAPGPFSSKPQRSQLQIFSSVLQTSLLFLLMGLRASGKDSAPTVVSGILGGSVTLPLNISVDTEIENVIWIGPKNALAFARPKENVTIMVKSYLGRLDITKWSYSLCISNLTLNDAGSYKAQINQRNFEVTTEEEFTLFVYEQLQEPQVTMKSVKVSENFSCNITLMCSVKGAEKSVLYSWTPREPHASESNGGSILTVSRTPCDPDLPYICTAQNPVSQRSSLPVHVGQFCTDPGASRGGTTGETVVGVLGEPVTLPLALPACRDTEKVVWLFNTSIISKEREEAATADPLIKSRDPYKNRVWVSSQDCSLKISQLKIEDAGPYHAYVCSEASSVTSMTHVTLLIYRRLRKPKITWSLRHSEDGICRISLTCSVEDGGNTVMYTWTPLQKEAVVSQGESHLNVSWRSSENHPNLTCTASNPVSRSSHQFLSENICSGPERNTKLWIGLFLMVCLLCVGIFSWCIWKRKGRCSVPAFCSSQAEAPADTPEPTAGHTLYSVLSQGYEKLDTPLRPARQQPTPTSDSSSDSNLTTEEDEDRPEVHKPISGRYEVFDQVTQEGAGHDPAPEGQADYDPVTPYVTEVESVVGENTMYAQVFNLQGKTPVSQKEESSATIYCSIRKPQVVPPPQQNDLEIPESPTYENFT
What is the function of this protein?
Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family.  SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.  Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2.  May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction.  Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to increased IL-17 secretion; the costimulatory activity requires SH2D1A (PubMed:22184727).  Promotes recruitment of RORC to the IL-17 promoter (PubMed:22989874).  May be involved in the maintenance of peripheral cell tolerance by serving as a negative regulator of the immune response.  May disable autoantibody responses and inhibit IFN-gamma secretion by CD4(+) T-cells.  May negatively regulate the size of thymic innate CD8(+) T-cells and the development of invariant natural killer T (iNKT) cells (By similarity).
What are the official names of this protein?
T-lymphocyte surface antigen Ly-9, Cell surface molecule Ly-9, Lymphocyte antigen 9, SLAM family member 3, SLAMF3, Signaling lymphocytic activation molecule 3.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell membrane.
Protein: LV552_HUMAN
Sequence: MAWTLLLLVLLSHCTGSLSQPVLTQPSSHSASSGASVRLTCMLSSGFSVGDFWIRWYQQKPGNPPRYLLYYHSDSNKGQGSGVPSRFSGSNDASANAGILRISGLQPEDEADYYCGTWHSNSKT
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 5-52.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: ISPE_BACFR
Sequence: MITFPNAKINLGLNITEKRPDGYHNLETVFYPIPLEDALEITILNDSKQKFVLHQSGLEISGEPETNLVVKAYLLLEQEFQLPPVDIYLYKHIPSGAGLGGGSADAAFMLKLLNEKFNLHLADEKLEEYAAILGADCAFFIKNKPTFAEGIGNIFSPVDLSLKGYQLVLVKPDVFVSTRDAFSQIQPHYPDHSLKEIIRRPVSEWKNCMFNDFEKSVFPQYPVIEEIKKELYSKGAIYAAMSGSGSSVFGLFSPEEKITKMDFEAAFCFQTELK
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CHA2B_LYMDI
Sequence: MNSFALLLVCIQACLVQSVFSQCTSRAAVAADRGIIGGYGLGAPYGLGCGYGLEAPYGWAGYADYGYGLDAYGGIGEGNVAVAGELPVAGTTAVAGQVPIMGAVKFGGDVCAAGSVSIAGKCDCGCGEVYGYGLGAPYLY
What is the function of this protein?
This protein is one of many from the eggshell of the gypsy moth.
What are the official names of this protein?
Chorion class A protein Ld2/Ld41.
What is the protein family that this protein belongs to?
Belongs to the chorion protein family.
Protein: OFOA2_AERPE
Sequence: MVDISLIIGGPQGGGIESAGQIAIKSMVLLGYEVLGSREYHSNIMGAHSYYHLRVQQHRPRSLKLPVDGVLALDAESVFTHFRDVRPGGILVYDPGTKSTRVDAIQPMAGPLKKRLKSLFDSRGMQPVVESAVKLAEEAGARIVGLPLKEMLKTLSERTGAPVARVSRALNTLGLASMLYMLGVPVEYIEKAISLQFAGKEKVINMNVEAVRIAVDYVREAFGEPESRLPPGPRRGQTMMVATGNDLVAMGKIVGGLGVITYYPITPSSDEALYVEKHSYISIDGPLAEKLGYDKIAVAIVQMEDELASINAVLGAAAAGARASTTTSGPGFSLMNEAVSLAVEAEIPVVVTLWMRAGPSTGMPTRTGQQDLLHSIFSGHGDAPKIVLASGDHVEAFYDAIKAFNWAEEFQTPVIHLLDKYLASSMVSLAREDLDPSKVPITRGKLLDNPPADYRRYEVVEDGISPRARLGSATMVITGLEHDEYGYATEDPVMREIMMFKRERKFKVIEERIPDEEKAVLHGDSEASVALVSFGSTKQPILEALEMLRDEGVRARFAQVRLLYPFPGRLVEEMLEGVEKVIMVEQNLLGQLAMLLRAHTSIKPDSSIVKINGRPLYSFEVAGAVKRILETGEERVVVSHGS
What is the function of this protein?
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate, glyoxylate and 2-oxoglutarate to form their CoA derivatives.
What are the official names of this protein?
2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha, OFOR2.
Protein: PURT_XANC8
Sequence: MTTLGTPLSPSATRVLLLGSGELGKEVAIELQRFGVEVIAADRYANAPAMQVAHRSHVLDMLDPQALRALIAQEQPHLIVPEIEAIHTETLVALEHEQGQKVIPTARAARLTMDREGIRRLAAETLGLPTSPYRFVDTAAEYREAIATVGLPCVVKPVMSSSGKGQSTLRSEADIDAAWDYAQTGGRAGAGRCIVEGFIDFDYEITLLTVRHAGGTSFCDPIGHWQKDGDYRESWQPQPMSAAALRRSQEIAQAITDELGGWGLFGVELFVKGDEVWFSEVSPRPHDTGLVTLVSQELSEFALHARAILGLPVGAENGGVIRQSGPSASCALLAHGNGVPVFDNVAEALRDPDTALRLFGKPRVDGHRRVGVTLARAGSIDAAREKARVAAAALTIQLRD
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: DPOL_HBVC5
Sequence: MPLSYQHFRKLLLLDDEAGPLEEELPRLADEGLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPVFNPEWQTPSFPHIHLQEDIINRCQQYVGPLTVNEKRRLKLIMPARFYPNLTKYLPLDKGIKPYYPEHAVNHYFKTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQELQHGRLVFQTSTRHGDESFCSQSSGILSRSPVGPCVRSQLKQSRLGLQPQQGSMARGKSGRSGSIRARVHPTTRRSFGVEPSGSGHIDNSASSTSSCLHQSAVRKTAYSHLSTSKRQSSSGHAVEFHNIPPSSARSQSEGPIFSCWWLQFRNSKPCSDYCLTHIVNLLEDWGPCTEHGEHNIRIPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRGSTHVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLVGSSGLPRYVARLSSTSRNINHQHGAMQDLHDSCSRNLYVSLLLLYKTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLFTSITNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGSWGTLPQEHIVLKLKQCFRKLPVNSPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQSKQAFTFSPTYKAFLCKQYLNLYPVARQRSGLCQVFADATPTGWGLAIGHRRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLLLPFRPTTGRTSLYAVSPSVPSHLPDRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: THIG_KLEP3
Sequence: MLRIADKTFESHLFTGTGKFAAPEVMVEAIRASGSQLVTLAMKRVDLRQHNDAILAPLLAAGVSLLPNTSGAKTAEEAVFAARLAREALGTHWLKLEIHPDARWLLPDPIETLKAAELLVCEGFVVLPYCGADPVLCKRLEEAGCAAVMPLGAPIGSNQGLETRAMLEIIIEQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVTMARAFRMAVDAGLLARQAGPGARSTQAQATSPLTGFLEALA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODP2_CUPNH
Sequence: MSQAIEIKVPDIGDYDAVPVIEVHVKPGDSINAEDALVTLESDKATMDVPSPQAGVVKDVRIKVGDNVSEGSVLVMLEAANEPAAAPAPAAAAPAPAAAAPAPAPAPAAAPAAAPAAGGGGTIEVKVPDIGDYDAVPVIEVHVKAGDTINAEDAVVTLESDKATMDVPSPQGGVVKEVKVKVGDNVAEGTLLLILEGAAASAAPAAAAAAPAPAASAPAPAPAPAAAAPAPAAAPAAAPAAAGVTGKAAHASPSVRKFARELGVDVSRVPGTGPKGRITQEDVQGYVKGVMSGQAAAPAQAAAAGAGGGELGLLPWPKFDFTRFGEVESKALSRIKKISGANLHRNWVMIPHVTNHDEADITELEAFRLQLNKENEKSGIKVTMLAFMIKATVAALKKFPNFNASLDGDNLVLKKYFNIGFAADTPNGLVVPVIKDADKKGVLEISQEMSELAKLARDGKLKPDQMQGGCFSISSLGGLGGTYFTPIINAPEVAIMGVCKSYQKPVWDGKQFAPRLTLPLSLSWDHRVIDGAEAARFNTYFGQLLADFRRILL
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: PROB_PECAS
Sequence: MSGSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQQHAAGHRIVIVTSGAIAAGREHLGYPELPATIATKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTMRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILADADKLLLLTDQAGLFTADPRNNPDAELIREVTGINDALRSIAGDSVSGLGTGGMSTKLQAADVACRAGIDVVIAAGSKPGVIGDVIADISVGTRFHALDTPLESRKHWIFGAPPAGEITVDDGALSAILERGSSLLPKGIRTVEGNFSRGEVIRVRSLAGRDVAHAVTRYNSDALRLIAGHHSQQIAEILGYEYGPVAIHRDDMIIN
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4393_RALSO
Sequence: MPLIQVTLIEGRTMEAKAALIGSLTQAAVATLGAPRESVRVIIQEVPAAHWGVAGVPKSAAKEPPRDSKA
What are the official names of this protein?
Probable tautomerase RSp0893.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: AAEA_SALPA
Sequence: MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITHVNVHDNQLVKKDQVLFTIDQPRYQKALAEAEADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYAGEFITRGSTAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSVAAGVTNASSTSDAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWPAGTTATVVITGKQDRDASQDSFFRKLAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TPIS_THEVB
Sequence: MIRDNPCGTLDQVKFRRGKSRGVRPKVLAGNWKMHKTQQEAVAFLQEFLGELVDTPSDREVVLCVPYTCLSVLSKSLHGTRVKLGAQNVHWADQGAFTGEISPPMLVELGVRYVIIGHSERRQYFGETDATVNQRLRAAQSHGLTPILCVGETKAQRAAGETENHIFQQLALDLVDVDQTNLVIAYEPIWAIGTGDTCEETEANRVIGLIRSQLHNPDVPIQYGGSVNANNIDAIMAQPEIDGVLVGGASLQPQSFGRIVNYKPL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_ACTSZ
Sequence: MSMQDPIADMLTRIRNGQAANKVAISMPSSKLKVAIANVLAAEGYIESVKVLEGAKPELEITLKYFQGKPVVESIQRVSRPGLRIYKRKDELPKVMGGLGVAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CSPA_SALVI
Sequence: DKGFGFITPDDGSKDVFVHFSAIQNDGYKSLDEGQKVSFTIESGAK
What are the official names of this protein?
Major cold shock protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_ECO55
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVIGTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: SYA_BORA1
Sequence: MKSSEIRQKFLQFFQSKGHSIVPSSSLVPGNDPTLLFTNSGMVQFKDVFTGKEKRPYTRATSSQRSVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKQDAIRFAWELLTTVYKLPVEKLWVTVYQEDDEAYDIWAKEVGVPTERIIRIGDNKGARYASDNFWQMGDTGPCGPCTEIFYDHGPDIWGGPPGSPEEDGDRYIEIWNLVFMQFERDAAGNMTPLPKPCVDTGMGLERIAAVLQGVHSNYEIDLFQKLITAAARETGVQDLHDNSLKVIADHIRACSFLIVDGVIPSNEGRGYVLRRIVRRALRHGYKLGQTKPFFYRLVPDLVAQMGEAYPELANMAERVGQVLKQEEERFGETLEHGMKILDVALAQVPKGGLLDGNTLFTLYDTYGFPVDLTADICREREVEIDMAGFEAAMERQRDQARAAGKFKMAEGLNYEGAQTRFEGYEQLELSGAKVTALYVDGTQTDQVRAGQQAVVVLDATPFYAESGGQVGDTGLLVADGLRFAVADTLKVQAGVFGHHGLLEEGVLKVGDTLLARVDAVRRARTVRNHSATHLMHKALREVLGAHVQQRGSLVDPDKTRFDFAHDAPMTAEQIARVEAIVNAEVLANQAAQARVMAYDDAVKGGAMALFGEKYGDTVRVLDIGFSRELCGGTHVSRTGDIGLFKIVSEGGVAAGVRRVEAITGDNALVWVQEQNALLQRAAGVLRSPVAELPERIAQVQDQVKALEKDLEQARAKLAASAGNDLADKSAVEIKGVKVLAAVINDVDPKALRGMVDNLKDKLKPAIVLLAASADGKISLVGGVTADQTAKVKAGDLVGFVAAQVGGKGGGRPDMAMGGGTDVAALPAAIASVQDWVNERL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_METMJ
Sequence: MEIQFKDGLVPVIVQERRNRDVLMLAYANAEALELTRTTGYAHYYSRSRQKLWKKGEESGHVQRICRILVDCDEDAILYEVEQTGAACHTGHASCFYRTVEGEEIAGLVFDPEKVYANKGE
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.