PharMolix/UniProtQA huggingface dataset:
Protein: Y1627_HAEIN
Sequence: MTIQRILPSARLSEVSIHNNLAYFAGQVPELTIEQNAYEQTKEVLGLIDKLLAKIGSNKSNILTAQIFLADMKDYAQLNQAWDEWVDHVSPPSRATVEAKLADPHWKVEIVIIATC
What are the official names of this protein?
RutC family protein HI_1627.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: NTPPA_CLOBL
Sequence: MKNIILASASERRQELLKRILEDFQIIVSDFDESSIPFKDNISSYVMNLAEGKARSVSKKIMDQDNNLVIGCDTLVAFNNKILGKPKDKKDAFEMLQALSDNEHEVYSGLAILDVKSNKIIKDFVCTKVKFSKLTSFQIEKYVNTGDPMDKAGAYGIQGKAGVFVENINGCYYNVVGLPLNKLNSMLMEMGVNL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMT2_CRYNB
Sequence: MASYTPSSSRPHTPLGLSPRGSYTNLASAAYDASSPGGHGAKDEKERLRAEREVQEALLKAQDGVEKAKKEEVCMPASTTVLPILSYCVASIMMTVVNKFVVSGRQFTMTFLLLAIQSFVCVACVWLAKRIGVINFRDWDMNDAKAWFPVSSLLVAVIYTGSKSLQFLSIPVYTIFKNLTIILIAYGEVIWFGGHVTPLTLCSFFLMVGSSVIAAWADISTTLSKLSAGVAVVDPISGADVPLSSISVMDTMNVGYLWMFINCLASAGYVLFMRKRIKVTGFKDWDSMFYNNLLSIPVLFVFSLIIEDWGAASFSRNFPEEGRAFLLSAIAFSGAAAVFISYSTAWCVRICGATTYSLVGALNKLPVAASGILFFGDPVNFGNVSAILVGGVSGIVYAVAKTNQAKVEKSKQARGGESKA
What is the function of this protein?
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
GDP-mannose transporter 2, GMT 2.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MURC_BACC7
Sequence: MTVYHFVGIKGTGMSSLAQILHDMKHTVQGSDYEKRFFTQTALEKRSISILPFDKSNVKEGQVIIAGNAFPDTHEEIVAAKELNIPVHRYHHFLGDLMNQYTSVAVTGAHGKTSTTGLLAHVMQGAHPTSYLIGDGTGHGVENSKYFVFEACEYRRHFLSYNPDYAIMTNIDFDHPDYFTDINDVFSAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGTIFDVFVRNTYYDTFKITGYGNHSVLNALAVIALCHYENVDVEAVKHQLTTFEGVKRRFNEKPMGEQVIIDDYAHHPTEINATIEAARQKHPEREIVAVFQPHTFSRTEKFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDVLKKHKNGVLIFMGAGDIQKFEAAYVKEVQVAEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_CLOB8
Sequence: MIQVKICGITNKNEIKYLNILKPEYMGFVFTKSKRQVTVREAKQLSNNLDKQIKIVGVFKDNSIDEILDVINILPLNIIQLHGKEDENFISSLKARVEKSVSIWKALSISDAENIRKYADHKYRDSIDNILIDGDKPGSGETFPLEDICELLKVDSNKENNCNLTNNTCSFFLAGGITPENVAERIVKVSPYGIDVSSGIEITNEDGTRTKSFEKMRSLIEKVRAININ
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RS16_MAGSA
Sequence: MALKIRLSRGGAKKRPFYKIVVADARAPRDGRFIEKVGTYNPMLPNDNGQRWILDEDRVKHWLSVGAQPTDRLVRFFADKGLVAKPVRAEQTKQPQPKAKAQQRAKDQAERDAAAAAEAAAGE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MDAB_ECOL6
Sequence: MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYDVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRKDPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGMEPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG
What is the function of this protein?
NADPH-specific quinone reductase.
What are the official names of this protein?
NADPH:quinone oxidoreductase MdaB, Modulator of drug activity B.
What is the protein family that this protein belongs to?
Belongs to the oxidoreductase MdaB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAS3_RAT
Sequence: MDLYHTPAGALDKLVAHSLHPAPEFTAAVRRALGSLDNVLRKNGAGGLQRPRVIRIIKGGAHARGTALRGGTDVELVIFLDCLRSFGDQKTCHTEILGAIQALLESWGCNPGPGLTFEFSGPKASGILQFRLASVDQENWIDVSLVPAFDALGQLHSEVKPTPNVYSSLLSSHCQAGEHSACFTELRKNFVNIRPVKLKNLILLVKHWYRQVQTQVVRATLPPSYALELLTIFAWEQGCRKDAFSLAQGLRTVLALIQRNKHLCIFWTENYGFEDPAVGEFLRRQLKRPRPVILDPADPTWDLGNGTAWCWDVLAKEAEYSFNQQCFKEASGALVQPWEGPGLPCAGILDLGHPIQQGAKHALEDNNGHLAVQPMKESLQPSNPARGLPETATKISAMPDPTVTETHKSLKKSVHPKTVSETVVNPSSHVWITQSTASSNTPPGHSSMSTAGSQMGPDLSQIPSKELDSFIQDHLRPSSQFQQQVRQAIDTILCCLREKCVDKVLRVSKGGSFGRGTDLRGKCDVELVIFYKTLGDFKGQNSHQTEILCDMQAQLQRWCQNPAPGLSLQFIEQKSNALHLQLVPTNLSNRVDLSVLPAFDAVGPLKSGAKPLPETYSSLLSSGCQAGEHAACFAELRRNFINTRPAKLRSLMLLVKHWYRQVAARFEGGETAGAALPPAYALELLTVFAWEQGCGEQKFSMAEGLRTVLRLVQQHQSLCIYWTVNYSVQDPAIRAHLLRQLRKARPLILDPADPTWNMDQGNWKLLAQEAAALESQVCLQSRDGNLVPPWDVMPALLHQTPAQNLDKFICEFLQPDRHFLTQVKRAVDTICSFLKENCFRNSTIKVLKVVKGGSSAKGTALQGRSDADLVVFLSCFRQFSEQGSHRAEIIAEIQAQLEACQQKQRFDVKFEISKRKNPRVLSFTLTSKTLLGQSVDFDVLPAFDALGQLKSGSRPDPRVYTDLIQSYSNAGEFSTCFTELQRDFISSRPTKLKSLIRLVKHWYQQCNKTVKGKGSLPPQHGLELLTVYAWERGSQNPQFNMAEGFRTVLELIGQYRQLCVYWTINYGAEDETIGDFLKMQLQKPRPVILDPADPTGNLGHNARWDLLAKEAAAYTSALCCMDKDGNPIKPWPVKAAV
What is the function of this protein?
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response.  In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation.  Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation.  Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication.  Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L (By similarity).
What are the official names of this protein?
2'-5'-oligoadenylate synthase 3, (2-5')oligo(A) synthase 3, 2-5A synthase 3.
What is the protein family that this protein belongs to?
Belongs to the 2-5A synthase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EFTS_LISMF
Sequence: MANITAQMVKELREKTGAGMMDCKKALVETEGDMEKAIDYLREKGIAKAAKKSDRVASEGMTHVISNEKHAVVLEVNAETDFVAKNDNFQQLVDALAKQILAVRPDSLEDALKTEMPNGQTVQDYITEAITKIGENISLRRFEVKEKADNSAFGEYIHMNGRIGVLTLLEGTTDTTVAKDVAMHIAAINPKYISREDVSTEEVEHEKEVLTQQALNEGKPANIVEKMVEGRLKKYLSEISLEDQPFVKNPDITVGDYVKQSGGKVVSFVRFEVGEGIEKKEDNFVEEVMSQVKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGAP6_MOUSE
Sequence: MGRVGAGGTAREAATGSLLLLLLLLARPPPAAASNSKESEAGLVSEHFSQAPQKLSFYSWYGSTRLFHFRVPPDTVLLRWLLHVSQGSPSCTDEEITVHFRYGAPPVINPLGTSFPDNTLSHASFHIRALLSTLMLDNTSVNISHPAPGDWFLVAHLPPSSQKIQVKGFVPTCAYIFQPDMLVMRVVEVSTLEPDVPLPQTLLSYPSYLKIFVPEYTQELRLELQGCVSSVSPGCPVRVTVGATTLPRNFQRVLTCTGLAPSCHLLLSSPPWGRWLQVTFESLAEPHVTVGFTAKAVFTVCRPWSVTIHHLIQNNPNQTYDTSAIQLSQSAVHRDLGRSSRVDSGPFCLLNYPVLREDTDVVSVHFQPLNGAFVLVHSSMPSVMQLRLDTGMDSGGSFIIVLRTNKTEVTNGTLVAACVNAASPFLSFNTSLNCTTAFFQGYPMFLRASSHMANLIMPFPETDNWYLSLQLVCPESPEDCEQAVVRVETILYLVPCLNDCGPYGQCLLLRRYGYVYAGCSCKAGWRGWSCTDNSTAQTVAQQRAAALLLTLSNLMFLAPIAISLHRSFLVEASVYFYTMFFSTFYHACDQPGEAVLCILSYDTLQYCDFLGSGASTWVTILCMARLKTILKQVLLVLGTLVIAMSLQMDRRGIWNLMGPCVFAFVIMASMWIYRCGHRGQCYPTSWQRWVFYLLPGISMASVGIAMYTSMMTSDNYYYTHSIWHILLAGSAAFLLPPREEKAGSWACLQKFPCHYQICRNDRDELYTVT
What is the function of this protein?
Involved in the lipid remodeling steps of GPI-anchor maturation.  Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchor proteins (GPI-AP).  Has phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI.  Required for the shedding of the GPI-AP TDGF1, but not CFC1, at the cell surface.  Shedding of TDGF1 modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells.  Also indirectly involved in the translocation of RAC1 from the cytosol to the plasma membrane by maintaining the steady state amount of CAV1-enriched plasma membrane subdomains, stabilizing RAC1 at the plasma membrane.
What are the official names of this protein?
Post-GPI attachment to proteins factor 6, GPI processing phospholipase A2, GPI-PLA2, M83 protein, Transmembrane protein 8, Transmembrane protein 8A.
What is the protein family that this protein belongs to?
Belongs to the TMEM8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Protein: RNM5_CLOAB
Sequence: MIKEVIVVEGRDDITAVKRAVDAEMIAVGGFGINSKIISKIKEAQKRRGVIVLTDPDFAGEKIRSIISKRVKGIKHARISQSEGTKNGDIGVENASPESIIRALNNAKCETQKKTYEFTIEDMLFFKLVGNSEAKKRRDLVGNELGIGYSNGAQFLSRLNNFGISKEELINAVNTVNRRYYDEGI
What is the function of this protein?
Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor.  Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
What are the official names of this protein?
Ribonuclease M5, RNase M5, Ribosomal RNA terminal maturase M5.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease M5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIRL4_ARATH
Sequence: MDLMQMDKRLDSTEQVVEEIMRIHRSLPARPGIDEVEAAKGLIDNVEKEDQACLEAIARQRKSSEVPGELFMVLQEMKKGYVQFRSKEQIREALKLLDLESVHSLFDDFIQRASNCIASPSSNGSVSSRPPLPPATTTAARSDSQSSLNFSERAPVRPKDMVSRDDSFVTKSKPSSLYSDGFAAPPRRPQILDSTLTTGNDGEKLSLIKLASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKLSSLTSLDLSENHIVVLPNTIGGLSSLTKLDLHSNRIGQLPESIGELLNLVYLNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVETNDIEEIPYSIGGCSSLIELRADYNKLKALPEAIGKITTLEILSVRYNNIRQLPTTMSSLASLKELDVSFNELESVPESLCFATTLVKLNIGNNFADMVSLPRSIGNLEMLEELDISNNQIRVLPDSFKMLTKLRVFRAQENPLHIPPRDIAEKGPQAVVQYMNDLVETRNAKSLMVKPKKSWVQMCFFSKSNKRKQSSMEIV
What is the function of this protein?
Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction.
What are the official names of this protein?
Plant intracellular Ras-group-related LRR protein 4.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
Protein: ZRT1_SCHPO
Sequence: MSLNNLSNSYNQYLAQESHQILRHLFLNKQYSPLVKRDDDSSATVTCGGDANEFNEYGHLGYRIGAIFVILATSLIGMNLPLVLSKITKNRPNVYIEYLYLFARYFGSGVILATAFIHLLAPACNKLYDPCLDDLFGGYDWAPGICLISCWFILLLEVLLNRYVEWRFGMEIGDHHGPTLGAKQHSHSHEDGAHGVHEHPVYDIEECADGVEHECVKDDLEEVKLEPYTNTDSTDLTTKEEARSFLLKQQLTAFIILESSIILHSVIIGLTTAVSGEEFKTLFPVIIFHQAFEGCGLGSRLAGMAWGPKTAWVPWVLGVIYSLVTPIGMAAGLGVREHWDPLAHGSYAAQGVLDAISSGILVYAGLVELLAHDFLFSPERERNWYKLIYLLACSMAGTGVMALLGKWA
What is the function of this protein?
High-affinity zinc transport protein.  Regulates intracellular zinc levels.
What are the official names of this protein?
Zinc-regulated transporter 1, High-affinity zinc transport protein zrt1.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
Protein: RL2_RICRS
Sequence: MALKNFNPITPSLRELVQVDKTSLWKGRPLKSLTKGISKTGGRNNQGRITSWHRGGGHKKLYRIIDFKRNKIDVSAIVERIEYDPNRTAFIALIKYEDGEYSYILAPQKLSVGDRVISSQDADIKIGNCLPLKCIPIGTTLHNVEMKVGKGGQIARSAGTSVDLVGKDSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRNRWLGWRPHVRGVAMNPVDHPHGGGEGKTSGGRHPVTPWGFPTKGKKTRKNKRTSKFIVKKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: YCHH_ECOL6
Sequence: MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAHGAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYDKRCRRSDNRRHS
What are the official names of this protein?
Uncharacterized protein YchH.
Protein: ISPG_VIBVY
Sequence: MHNESPIIRRKSTRIYVGDVPIGDGAPIAVQSMTNTRTTDVAATVAQIKALENVGADIVRVSVPTMDAAEAFKLIKQQVSIPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVDCARDKNIPIRIGVNGGSLEKDLQMKYGEPTPEALVESAMRHVDILDRLNFDQFKVSVKASDVFLAVDSYRLLAKKIDQPLHLGITEAGGARAGAVKSAVGLGMLLAEGIGDTLRISLAANPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNALEERLEDIITPMDVSIIGCVVNGPGEAEVSHLGLAGSNKKSAFYEDGKRQKERFDNEDLVNQLEAKIRAKAARMDESNRIDIKVQN
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: NDK_BURO1
Sequence: MAIERTLSIIKPDAVAKNVIGQIYSRFEGAGLKIVASRMAHLSRADAEKFYAVHAARPFFKDLVDFMISGPVMIQVLEGEGAILKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAAETAAVEIAFFFPEMNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: MSRA_XYLFT
Sequence: MVMTIEALKHLGRVDESRVGRTEPLPLDNRHYVNGHPLCDSFPGLALIQFGLGCFWGAERLFWQLPGVFSTAAGYAGGGVPYPTYREVCSGETGHAEVVLVVYDHTVISFEQLLQTFWESHDPTQGMRQGNDIGTQYRSVIHCTTSEQYAAASASREVYQQQLNTAGYTAITTEILHPAPPFYYAENEHQQYLAKHPNGYCGLGGTGVTCAIRLQV
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: Y1875_ALBFT
Sequence: MLHYAVVFFVIALIAALFGFGGIAASAVSIGKILFIVFAILAVASFLFGLIKKR
What are the official names of this protein?
UPF0391 membrane protein Rfer_1875.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3753_YERPA
Sequence: MSQRDTGAHYENLARRHLERAGLVFQAANVAFRGGEIDLIMRDGDAWVFVEVRFRRNDLFGGAAASITPRKQQRLHLAAAVWLAQRGASFATTSCRFDVVAITGNQLEWLPNAFNTD
What are the official names of this protein?
UPF0102 protein YPA_3753.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RIMM_CLAMS
Sequence: MWWTPIPEDIVRDPAAFRVGRLTKAHGLKGAVKLELFTDDPDKRFVPGAEFSLQVPDSSPWHGRTLTLTELRWYNSHPVGFFEGVADRTAAESLAKAILWMTPPADEPAEPDAWYDHQLVGLKVLRDGVEVGTVSLVDHFPAQDLLHVDTPSGTVLVPFVQAIVPSVDVEAGTLVITPPLGLFEEIPDEQPTPSATSDAEPGSAPEGDDAR
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHP1_BACSU
Sequence: MTAVNDKISTIVNGKRVITKKPELLAPAGNLEKLKIAVHYGADAVFIGGQEYGLRSNADNFTIEEIAEGVEFAKKYGAKIYVTTNIFAHNENMDGLEDYLKALGDANVAGIIVADPLIIETCRRVAPNVEVHLSTQQSLSNWKAVQFWKEEGLDRVVLARETSALEIREMKEKVDIEIESFIHGAMCIAYSGRCVLSNHMTARDSNRGGCCQSCRWDYDLYQTDGANAVALYGEEDAPFAMSPKDLKLIESIPKMIEMGIDSLKIEGRMKSIHYVATVVSVYRKVIDAYCADPENFVIQKEWLEELDKCANRDTATAFFEGTPGYEEQMFGEHAKKTTYDFVGLVLNYDEDTQMVTLQQRNFFKKGDEVEFFGPEIENFTHTIETIWDEDGNELDAARHPLQIVKFKLDKKIYPSNMMRKGK
What is the function of this protein?
Involved in prephenate-dependent formation of 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs, the first step in 5-methoxyuridine (mo5U) biosynthesis.
What are the official names of this protein?
tRNA hydroxylation protein P1.
What is the protein family that this protein belongs to?
Belongs to the peptidase U32 family.
Protein: PRLR_PIG
Sequence: MKENVPSTVVFILLLFLNISLLNGQSPPGKPEIFKCRSPEKETFTCWWKPGADGGLPTNYTLTYHKEGETFTHECPDYKTGGPNSCYFNKKHTSIWTIYIITVNATNQMGSSSSDPRYVDVTYIVEPDPPVNLTLELKKPEDQKPYLWIKWLPPTLVDVRSGWLTLQYEIRLQPEKTAEWETHFAGQQTQFKILSLYPGQKYLVQVRCKPDHGFWSEWSPESSIQIPNDFSMKDTTMWIFVAILSAVVCLIMIWAVALKGYSMVACILPPVPGPKIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDSEDQQLMPAHSKEHPSQGRKPTHLDPDSDSGRGSCDSPSLLSEKCDEPRANPPKFHTPEGIEKPGDPETNLPRPQDPQSTSVESKLLYFHADGSKSSTWPLPQPPILHDPGSSYHNLADVGQLVLGTAGATAALLEKTDRHAFNPPKTTETGGEGRATEQKESESFHSKTDQGTVWLLPQDKGPFVSPKPMEYVEIHKVSKDGALALLPKQQENGDRPEKAGAPETSKEYAQVSRVMDNHILVLVQDPRARNVAPFEEPTKETPPSRPQNPAAKDLASFTTAPGHCRHPLGGLDYLDPAGFMHSFQ
What is the function of this protein?
This is a receptor for the anterior pituitary hormone prolactin.
What are the official names of this protein?
Prolactin receptor, PRL-R.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 1 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TRMD_GLUDA
Sequence: MTWRATVLTLFPDMFPGPLGQSLAGRALEGGLWSVEARNLREYGLGRHRVVDDTPFGGGAGMVMRPDVVSAAIRDVAPAGRPLVYPTPRGRPLRQDDVRRYAGGPGLVVLCGRYEGVDERALEACGAEQVSIGDYVLSGGEMAALVLLDSCVRLIPGVMGSDASGTEESFSDGLLEYPHYTKPASWEGRDVPDILLSGHHAAIAGWRQTESETATRTRRPDLWAAHLERTGCTDRQF
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_ECOLU
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: P0_BWYVG
Sequence: MQFVAHDNFHTLEVRKVRYLHSRQVTFLLAGLLLNIEQFVKAIKERNNEFKIDIFLRSLLYQLPLHLGDHVHDDVRKSLLVPEPELCAWFSLQTGYAPASTSGRVNLYVPGTKTSRRRIIQRSLASNFSEKFKRFPECLFVGFEHFQRFLSIWTRDAERRLFSGCREIPVGSHTLVELANLGELLRVMVASEQFHNSRLLSRLAVHCYKIYGEDGFIS
What is the function of this protein?
Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  The P0 protein suppresses local PTGS using its F-box-like domain to mediate destabilization and degradation of the AGO1 protein (By similarity).
What are the official names of this protein?
Suppressor of silencing P0, Protein ORF0.
What is the protein family that this protein belongs to?
Belongs to the polerovirus P0 protein family.
Protein: IDI2_STAEQ
Sequence: MSDSQREQRKNEHVEIAMSQKDALVSDFDKVRFVHHSIPSIDVSQVDMTSHTTKFDLAYPIYINAMTGGSDWTKQINEKLAIVARETGIAMAVGSTHAALRNPNMIETFSIVRKTNPKGTIFSNVGADVPVDKALQAVELLDAQALQIHVNSPQELVMPEGNREFASWMSNIESIVKRVDVPVIIKEVGFGMSKETLQALYDIGVNYVDVSGRGGTNFVDIENERRSNKDMNYLSQWGQSTVESLLESTEFQDRLNIFASGGLRTPLDAVKCLALGAKAIGMSRPFLNQVEQSGITNTVDYVESFIQHMKKIMTMLDAPNIERLRQADIVMSPELISWINQRGLHLNRK
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANE_GLAP5
Sequence: MSRLTKQQILEQLKNGLIASCQPVDDGPMDSPEIVAAMAKASVIGGAAGLRIEGIDNLKAVRKVVDVPIVGIVKRDLPDSPVRITPFLQDIDDLYHAGADIIAFDGTDRVRPTTIEACARRIQELGAMSMADCSNYKEGMYCQELGVDLIGSTMSGYTGGETPDEPDVQLVRDLVASGCRVMAEGRYNTPELAAVAIENGAYAVTVGSALTRLEHIVSWFVTAIDDRKTGA
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: OTOL1_ONCKE
Sequence: MPSLRLLAILTTLLAVVLIATQSSATRTTRRPKPQNTKKPPRGGGTGGGGGGGDQPARLGFRQTTTTMAPSSSLGTDETTEDTMTDAYSLSPTDSTTYAGDAYPTEFHTDSMALPGAGMGNYTLDYSHCYLNVCECCPPEKGRGPPGERGPPGPGAERGLPGVPGEKGDVGLMGPPGLDGMPGATGLEGDKGDKGDQGDTGMPGAPGILGKEGPKGDLGPKGEKGETGLPGLKGDLGERGKPGWNGTQGEKGDLGKIGPAGPSGLTGPMGQNGQKGEMGECPTGEKGEKGEAGLPGPPGPRGLVGTPGVNGTNGLPGPVGLRGQLGSPGGKGEAGGRGPPGLRGMPGPKGEKGPKGPRGVRGPKGPQGETAEQIRSAFSVGLFPSKSFPPPGLPVKFDKILYNEEEHWDPMLSKFNCTHPGVYVFSYHITVRNRPLRAALVINGVKKLRTRDSLYGQDIDQASNLALLRLASGDQVWLETLRDWNGVYSSSEDDSTFTGFLLYADPKA
What is the function of this protein?
Collagen-like protein, which provides an organic scaffold for otoliths onto the sensory epithelium of the inner ear (PubMed:11856329).  Acts as a scaffold for biomineralization by sequestering calcium (By similarity).
What are the official names of this protein?
Otolin-1.
What is the protein family that this protein belongs to?
Belongs to the OTOL1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Localized in both the surrounding otoconial matrix and otoconia.
Protein: MGSA_KLEP3
Sequence: MELTTRTLSAQKHIALVAHDHCKDMLMKWVARHQALLAQHVLYATGTTGNLVSRATGLEVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNQPLDILIPDYPRYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: CUTC_ECO55
Sequence: MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLKSVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVDMPRMEKIMAAAGPLAVTFHRAFDMCANPLYTLNNLAELGIARVLTSGQKSDALQGLSKIMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSSDAHADEYSRYIVDGAAVAEMKGIIERHQAK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.