PharMolix/UniProtQA huggingface dataset:
Protein: EZRA_STAAE
Sequence: MVLYIILAIIVIILIAVGVLFYLRSNKRQIIEKAIERKNEIETLPFDQNLAQLSKLNLKGETKTKYDAMKKDNVESTNKYLAPVEEKIHNAEALLDKFSFNASQSEIDDANELMDSYEQSYQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANRHQFGEAASLLETEIEKFEPRLEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIPELIRETQKELPGQFQDLKYGCRDLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLELEEANDKLANINDKLDDMYDLIEHEVKAKNDVEETKDIITDNLFKAKDMNYTLQTEIEYVRENYYINESDAQSVRQFENEIQSLISVYDDILKEMSKSAVRYSEVQDNLQYLEDHVTVINDKQEKLQNHLIQLREDEAEAEDNLLRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDHEVRDVNEQFSERPIHVKQLKDKVSKIVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDYSNVDKSLNEAERLFKNNRYKRAIEIAEQALESVEPGVTKHIEEEVIKQ
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: RPW81_ARATH
Sequence: MPIGELAIGAVLGVGAQAIYDRFRKARDISFVHRLCATILSIEPFLVQIDKRSKVEGSPLREVNERLTCFLELAYVFVEAYPKLRRRQVLRKYRYIKAIETIELALRSIIVVDFQVDQWDDIKEIKAKISEMDTKLAEVISACSKIRA
What is the function of this protein?
Disease resistance (R) protein that induces localized, salicylic acid-dependent defenses (PubMed:11141561).  Confers resistance to powdery mildew (e. g.  Erysiphe cichoracearum UCSC1) (PubMed:11141561, PubMed:15155802, PubMed:17565954).
What are the official names of this protein?
Protein RESISTANCE TO POWDERY MILDEW 8.1, AtRPW8.1.
What is the protein family that this protein belongs to?
Belongs to the plant RPW8 protein family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TAUB_PSEAB
Sequence: MSRLTAEAISLSFEQRGQRRAILRDLSLGLAKGESLVVLGPSGCGKSTLLNILAGFQTPDQGRVQIDGRTLEGPGGERGVVFQDDALMPWLNALDNVALGLRIRGLGKAERTARARQVLQLVGLQEYAEQSVAELSGGQRQRLGLARALAVEPDFLLLDEPFGALDALTRERMQVLLLDLWKQTGKGLFLITHSVDEALFLATDLVVMDGPPARIVKRLPVDFARRYAAGETVRSIKSDPEFGRLRQALLDEFLDVAEAEHAH
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MSRP_ECOBW
Sequence: MKKNQFLKESDVTAESVFFMKRRQVLKALGISATALSLPHAAHADLLSWFKGNDRPPAPAGKALEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPYVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: DOHH_KLULA
Sequence: MSTNFEKHFEVDVDNCSLEQLRDILVNNSGKAPLANRFRALFNLKGHAEEFASKPEDALKATQYLAEAFGDESELLKHEVAYVLGQTKNMAGAPLLRDVLADDKQQCMVRHEAAEALGALNDVDSLDILEKYFKEDPLLEIRQTCELAIDRIKWETSEEGRREALQESLYSSIDPAPPFSLEKDYKIQELKDILNDQNRPLFERYRAMFRLRDIGNDEACLALASGFDDPSALFKHEIAYVFGQICNPVVVPHLKEVLARPEEAPMVRHEAAEALGSIATDDVLPVLKEHLKDSDSVVRESAIVALDMYEYENSNDLEYAPV
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GREA_ACIBS
Sequence: MQRYPMTPEGKIALEKELQHLKTVERPRITQAIAEAREHGDLKENAEYHAAREQQGFCEGRIQDIEGKLGTAQVIAVKDLEQNGRVVFGVTVTIENLDTEERNTYKIVGDDEADFKINKISVNSPIALGLLGKKEGDEVKITTPQGEVEYEVVSVEYL
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MTGA_CHRVO
Sequence: MSRILFKILAALVAAFLLYNLWVLGHIIYWRDHNPGASSFMNEQLARLQQDDPEAELRHKWVPYDKISPNLKRALIASEDARFVDHEGFDWDGIEAAFEKNLKKGKIVAGGSTISQQLAKNLFLSSGKTPWRKLEEALITVMLETVLDKRRIYEIYLNVIEWGNGVFGAEAASRYYFRTGASRLSSSQAAKLAAMVPNPRYYDEHRNAPGLARKTRIIQRRMAYVELP
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RIMK_ECOLC
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: FRIES_KALDA
Sequence: MWKLKIAEGGSDPYIYTTNNFVGRQIWEFDPQATDPQQLAKVEAARLNFYNHRHKIKPSSDLLWRLQFLEEKDFRQNIAQVKVEDGEEVSYEAATAALKRGVHFYSALQASDGHWPAENAGPMFFMSPLVMCLYITGHLNTIFTEEHRRETLRYIYYHQNEDGGWGFHIEGQSTMFGTVLNYICMRLLGEGPEGGQDNAVSRGRKWILDHGGATAIPSWGKTWLSIMGLCDWSGCNPMPPEFWLLPSYLPMHPAKMWCYCRMVYMPMSYLYGKRFTTHITPLILQLREELHTQPYDQINWKKVRHVCCKEDTYYPHPILQDLIWDTLYLTTEPLLTRWPLNKLIRERALKKTMKHIHYEDENSRYIVIGAVEKVLCMLACWVEDPNGDYFKKHLARVPDYFWVAEDGMKIQSFGSQHWDTAFFVQALLASDMTDEIRTTLAKAHDCIKKSQVKDNPSGDFRSMYRHISKGAWTFSDQDHGWQLSDCTAEGLKCCLLFSLMQPEVVGEAMPPERLYDSVNVLLYLQSKNGGMPGWEPAGESEWLELLNPTEFFENIVIEHEYVECTSSAVQALVLFKKLYPLHRRKEVERFITNGAKYLEDIQMPDGSWYGNWGVCFTYGAWFALEGLSAAGKTYNNCAAVRKGVDFLLNIQLEDGGWGESYQSCPDKKYVPLEDNRSNLVQTSWALMGLIYAGQADRDPTPLHRAAKLLINSQLEDGDFPQQEIAGVFKMNCTLHFAAYRNIFPIWALAVYRRFCNPNSEAISKPSK
What is the function of this protein?
Oxidosqualene cyclase that generates friedelin, a triterpenoid product with the maximum number of rearrangements possible.  Friedelin is probably required to coat the leaf exterior as defense compound against pathogens or herbivores.
What are the official names of this protein?
Friedelin synthase, KdFRS.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: Y266_HISS2
Sequence: MKFSFAALASAMLLTSTAAFAGIVTSSSNIDFLAIDGQKANKDLLKSTKSFNINESQTHQVVVRVSEIVRHGSDRSLYESDPIVVTFQGTNEDVVISAPKLENERDIKNFKDSPSVIVKTNSGKIIATKQEILKQEGFLPGANLIDTLSEYNASGSVASVSNFATAMPAVALGFAKAQKGKVVVQGENIAEQQLQFWFQQADKETQARFINWAKNQK
What are the official names of this protein?
UPF0319 protein HSM_0266.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: Y521_METJA
Sequence: MKNMDEERKYGLYSLIIGLLCVIGIVMLNGLICYVLYIIAVPSLLYGIGAFIIPKTRRKDAGKLPFRGY
What are the official names of this protein?
Uncharacterized protein MJ0521.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIF3A_DROSI
Sequence: MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGPENALLTPYIQSLKDVTIMRLIRQISQVYESIKFQRLLQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRNQMVSQYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVAQQERLKRMYPDRDEFLEALKKERASLYVEKLKKFEAALEAERKKRLADRIVRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRDRLSRELASERERTEKERDTWRPRGGDRPSASAGGSSEWRRAAPAVSERNDRGGERIERGGDRVERGGERIERGGERIERGGDRDRKDNEGADSSWRVRREPDTQRAAAPKDSGAPQSRDDKWRRGGERDRDFRNDGARRDRDDGPRRDRDDGPRRDRDDERGGFRRNDGPRRTDEPQRETGGNWRDAPRHADRENRRPAGERRDRDVRETRGDQRGSAPKEAASGGGGGNWRNAPATREEKPAAKRDQAQEKENKAGDDGEWTSVKRR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDB_METTH
Sequence: MFFMLETSICNIELRNPTILAAGVMGSMASSLNRIYRGGAGAVVTKSFSLRPNPGYRNPTTVEVTGGVINAIGLSNPGVEAFREELKLVDEEVPLIASVYGASPEEFASAAASVEEYADMIELNVSCPHAMAGCGASIGQDPELTFRVVSAVKDAVDVPISTKLTPNVTDIVEIAGSAEEAGSDALTLINSLGPGMKIDIKTARPILSNAFGGMSGPAIKPVAVRCVYDVYRSVDIPIMGVGGVRDFQDAVEFLFAGARAVQVGTAIMYDGPEVFMKICRGLEAFMMAEGFSSVDEMVGLAHD
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_ALIF1
Sequence: MEKVFNFCAGPAMLPVDVLAQAQKELVNWNGLGTSVMEISHRSKEFIKVAEESEQDLRDLLAIPDNYKVLFCQGGARAQFAAVPLNLLGGNTKADYVDAGYWAQSAVEEAQKYCTPNVINTIIDVDGKKAVQPASEWALSDDAVYVHFCPNETIDGIEINDLPVTDKPIVADMSSTILSRKIDVSKYGVIYAGAQKNIGPAGLTIVIVRDDLLDLASQTLPSVLNYGVLADKESMFNTPPTYAWYLAGLVFKWLKSNGGIDAMETHNRKKAAVLYDYIDQSDFYRNDVHSDNRSLMNVPFQLANPELDTKFLELADEAGLKALKGHRVVGGMRASIYNAMPLEGVEALVQFMKEFEEKYV
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y439_STAAR
Sequence: MGYLKRFALYISVMILMFAIAGCGKGNETKEGSKETQIKKSFAKTLDMYPIKNLEDLYDKEGYRDGEFEKGDKGMWTIYTDFAKSNKPGELDDEGMVLNLDRNTRTAKGHYFVTTFYRNGKLPDEKNYKIEMKNNKIILLDEVKDDKLKQKIENFKFFGQYANLKELKKYNNGDVSINENVPSYDVEFKMSNKDENVKQLRSRYNISTEKSPILKMHIDGDLKGSSVGYRKLEIDFSKRENSKLSVIEFLSYKPAKK
What are the official names of this protein?
Uncharacterized lipoprotein SAR0439.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MET2_SACPS
Sequence: MSHTAKSKTLQELDIEDIKETNPLLNLVQGQRIVQVPELVLESGVVLNNFPIAYKTWGTLNEACDNVLVICHALTGSADVADWWGPLLGNDLAFDPSRFFIICLNSMGSPYGSFSPLTINEQTGTRYGPEFPLCTVRDDVRAHRIVLDSLGVKSIACVIGGSMGGMLSLEWTAMYGNEYVKNMVALATSARHSAWCISWSEAQRQSIYSDPNYLDGYYPVEEQPVAGLSAARMSALLTYRTRNSFENKFSRRSPSIAQQQKAQKAEVRKPSTVSEHSLQIHNDGYKCKANGAIAGISGQKRQSVVSTTSSSDSLTSQSSMTSVSSVTGEVKDIKPAQTYFSAQSYLRYQGTKFINRFDANCYIAITRKLDTHDLARDRVEDITKVLSAIEQPSLIIGIQSDGLFTYSEQEFLAEYIPNSQLEKIESPEGHDAFLLEFKLINKLIVNFLKTNCKNIMDAKPRTWGGDVGNDETKTSVFGEAEEVTNW
What are the official names of this protein?
Homoserine O-acetyltransferase, Homoserine O-trans-acetylase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
Protein: FOLD1_ARATH
Sequence: MLMIARKALASAHTKAFRLATRDVHCFSSILVSPPLVSLDLPENWIPYSDPPPPVSFETEQKTVVIDGNVIAEEIRTKIISEVGKMKKAVGKVPGLAVVLVGEQRDSQTYVRNKIKACEETGIKSVLAELPEDCTEGQIISVLRKFNEDTSIHGILVQLPLPQHLNESKILNMVRLEKDVDGFHPLNVGNLAMRGREPLFVSCTPKGCVELLIRTGVEIAGKNAVVIGRSNIVGLPMSLLLQRHDATVSTVHAFTKDPEHITRKADIVIAAAGIPNLVRGSWLKPGAVVIDVGTTPVEDSSCEFGYRLVGDVCYEEALGVASAITPVPGGVGPMTITMLLCNTLEAAKRIFL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL21_GLOVI
Sequence: MVYAIVETGGKQVLVQPGRFYDVELLALDVEAALTFDKVLLVRHEGGAVVGRPTVEGAAVQGRILQHGKAAKVTVYKMRPKKGYRRKKGHRQRFTRVMIESIDFEGRSFTAEAKAEAVSST
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: VATA_METMP
Sequence: MVVGKIIKISGPVVVAEGMKGSQMFEVVKVGNEGLTGEIIQLTEDEAIIQVYEETAGIKPGEGVEGTGAPLSVELGPGMLKAMYDGIQRPLNEIENATDSIYIPRGVSVPSISREIKWDFEPTAAAGDEVITGDVIGTVQETASIVHKIMIPFGVSGKIKEIKAGSFTVEETVAVVETAEGEKEIMMMQKWPVRKPRPSKGKQAPVIPLITGQRVEDTFFGLAKGGASAIPGPFGSGKTVTQHQLAKWSDVDVVVYIGCGERGNEMTEVIEEFPHLDDIKTGNKLMDRTVLIANTSNMPVAAREASVYTGITIAEYFRDQGLGVLLTADSTSRWAEAMREISGRLEEMPGEEGYPAYLSSKLAQFYERAGRVECLGSENKQGFVCIVGAVSPPGGDFSEPVTSNTLRIVKVFWALDANLARRRHFPAINWLTSYSLYIDDIAGWWQQNTAADWRSLRDEAMSLLQKEAELQEIVQLVGPDALPDRERVILEIARMLREDFLQQDAYHEVDSYCSPLKQYNMLKIIMTFYKKGLDAVAKGADPAGISAVTVKGDIARMKYLTDDEFINTKVPEIINKMESELGALIK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: MNMA_ANAMM
Sequence: MQFIPSPAMVFDGSLNLDPLVSGKPPEETTVVVAMSGGVDSSVVAALLHERGYKVIGATMQLHSSSPASGAKSCCGSVDIYDAKRVASTLGFPHYVLDYEEVFRREVIDDFINSYKRGETPIPCVKCNQTVKFRDMLKAARAIGGDVVATGHYVRRVEIAGEQQILRGKDPQKDQSYFLFSVTSEQLKFLRFPLGDLAKSNVRLLAQQLNLEVADKPDSQDICFVPENSYREVLRNLDPASVKKGKIVHVDGRLLGEHDGISNFTVGQRRGLNISAPYPLYVVRLDAAQNTVVVGPQSALMKRALFVKNLNWLPDYNIPKRGLAVDARLRSSGATVRATITSDGDGYGTVVLEEDCVVSPGQACVLYDKERLLGGGWIYNKLCHEGA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLA2_OCEIH
Sequence: MTQTTVKNVKNYIGGEWIESRTEKTEDVFNPATGEVIAQVPISTTEDVHHAIEVANEAFKTWKEVPVPKRARILFKYQQLLVEHWEELAKLITLENGKNYAEAYGEVQRGIENVEFATGAPSLMMGEQLASIATELESGVYRYPIGVIGGITPFNFPMMVPCWMFPMAIATGNTFVMKPSERTPLLANRLAELLEEAGLPNGVFNIVHGAHDVVNGLLDHKKVAAISFVGSQPVAEYVYKRGTQNLKRVQALAGAKNHSIVLSDANLENATTQILNAAFGSAGERCMAASVVAVEEDVADEFVTLLTQKANEIKIGNGLDEGVFLGPVIRDQHKERTLQYIESGEEEGANLVRDGRTDEAAKQEGYFVGPTIFDHVTSEMKIWQDEIFAPVLSIARVNNLEEGVDLANESRFANGACIFTRDGGSVRRFRETIDAGMLGVNIGVPAPMAFLPFSGWKDSFYGDLHANGKDGLQFYTRKKVLTTKWV
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase 2, MSA dehydrogenase 2, Methylmalonate-semialdehyde dehydrogenase 2, MMSA dehydrogenase 2, MSDH 2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: RS20_BREBN
Sequence: MPNIKSAIKRTKTIEKRRAHRASQKSDLRTSIKNFEKAVAASDVALAKSTLLVAVKKLDKAASKGLIHKNAANRQKSRLMKKLNVLSAPVA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: NLPE_ECOLI
Sequence: MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQSWRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTDSKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEAAQSSLPMTPMTLRGMYFYMADAATFTDCATGKRFMVANNAELERSYLAARGHSEKPVLLSVEGHFTLEGNPDTGAPTKVLAPDTAGKFYPNQDCSSLGQ
What is the function of this protein?
Involved in copper homeostasis, could be involved in both copper efflux and the delivery of copper to copper-dependent enzymes (PubMed:7635807).  Required for efficient binding of stationary phase cells to hydrophobic surfaces, part of the process of biofilm formation (PubMed:11830644).  Functions during envelope stress responses; when overproduced induces degP through the activation of the two-component envelope stress response system CpxA/CpxR (PubMed:7635808, PubMed:15252048).  DegP induction seems to require membrane anchoring of this protein (PubMed:15252048).  Structural changes and/or interaction of the CXXC motif with its environment may lead to activation of the Cpx stress response (PubMed:17698001).
What are the official names of this protein?
Lipoprotein NlpE, Copper homeostasis protein CutF.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: NANR_ECODH
Sequence: MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.
Protein: MFM6_PHOSM
Sequence: MHRRRRDNLMTPAEMVASMKPPQSLSTEDDDGSRRDSESSADVLKSNEEFQARMIPEDDDANSVTAQPTWTVLSDTEIKSVLVVASFAAAISPFSTSTYYPAVFAISQDLGVSVSKINLTMSSYQIFQGVAPTITAAFADTYGRRPMFLVCFAIYFVANVGLALQNNFTTLLVLRCLQSTGSSGTFALAQAVTADITTRAERGRYLIYATLGSTLGPFLGPVIGGLLVKFLGWRSVFWFLLCMGTVFALLIFIFFGETARPIVGDGSVPPQSWNRSFLQIRSKGITSLKPNLASLERRKSRPNPLTSLALLWDRENFILSVSGGLLYAGYSSVTSVLASQLQQRYKYDAVQVGLCYLPVGFGSLLAYRTTVRLMDWNFEREAKKQGLVIVKNQQTDITRFDLEKARLGFVFPMILVCSVLLVAYGWQMHYHAPLAPILVTMFLIAIILTGVMNAIAALLTDVNRENAAAVGAAMNLTRLLLGAGAVAVVGPLNKSAGIGWTATVTAGLWVLMMPTLRMVYRDGFVWRAGENERVHASNVELAALVRS
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS).
What are the official names of this protein?
MFS-type transporter M6, Squalestatin S1 biosynthesis cluster protein M6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RNPA_MYCSS
Sequence: MLPARYRMTRSTEFSTTVSKGVRSAQPDLVLHMANVLDDPSGPRVGLVVAKSVGNAVVRHRVSRRLRHSVHPMLDELQPGHRLVIRALPGAASATSARLHQELSAALRRARPRVEASA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PRM1_DEBHA
Sequence: MKKQFLNYYEILSQVWFNKYTIILVLMTIKIYLFTNSILSNLTNFKAYTESICTSLDTYSTVIASLPEQLSKVINHMVASTLNSMKMQSLKMLMTIITIIKSLIVFYIDIFLGTYICILTAAIGGTVDFALDSTQSVLKSVNETIISVSEDIQDGLNGLSKVINTLLSGVDKVKSFFTNQDTDSTEYVDKVNLSIKALQNIKIPNSVLTDIDNFKDKVPDFNELQNTSKLVSKPFEIITQELNESAHFKNITVDQLKLASTPPVNFCSNSLDIDKFYSNLAKKVQFTSNIIIIVLLIMAMFAIASLVVVEYFKWRKSQRMINEILADKNQESYFVSTRNIMNKYNSSLIYYIEKFVTIPPSRKDNLYWLLSYITTPYSLTVLIIGLAGLFTVMLQFIILQIILKSFKSLTTELTGFKTQIITLMDNATSSYIKETNSYIGSQQKSINDELFGNIRTASTSVNSTINDFLMKMNTTINSVFANTPFSKPVNTLVYCTIGRKLIKIEQGLTWIVENLSVSLPQLPKNLTEDFMTNYSKDNHGIHKLTDNVTSGITFLLDTYKKSLLIELYISSAILGIWILQIIIGLTLIWYRSSSNCKARKPEKIQGEPTIGNPKPLTTEQRKEYGYPHIDPFNEKVDASSSIYSL
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein PRM1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.