PharMolix/UniProtQA huggingface dataset:
Protein: SODF_PLAVI
Sequence: MVITLPKLKYALNALSPHISEETLNFHYNKHHAGYVNKLNTLIKDTPFAEKSLLDIVKESSGAIFNNAAQIWNHTFYWDSMGPDCGGEPHGEIKEKIQEDFGSFNNFKEQFSNILCGHFGSGWGWLALNNNNKLVILQTHDAGNPIKDNTGIPILTCDIWEHAYYIDYRNDRASYVKAWWNLVNWNFANENLKKAMQK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe], FeSOD.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_LOPCO
Sequence: METATLIAIFISCSLVSFTGYALYTAFGQPSKELRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUOI_PSE14
Sequence: MFKYIGDIVKGTGTQLRSLVMVFGHGFRKRDTLQYPEEQVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETEDGRWYPDFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMADFKRQDLVYEKEDLLISGPGKNPDYNFYRVAGMAIGGKPKGSAQNEAEPINVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: POXL_PENOX
Sequence: MAPKDFFPPAPLDLDWDNIGIKVREVNGHVECAYNVATESWSEPQVVKGIDLTISGLSPALNYGQQAYEGMKAFRDPQGQIHIFRPEVHAARMAHSCEVVSIPPIPQAQFIRSVALAVSVNAEFVPPFDSSAALYIRPLAFGSGPQINLAQPEEYTFCVFVLPVTSLLGTKPVDALIMEEFDRTAPMGSGNAKVGGNYAPVLRWAAKARARGYGIPLHLDSKTRTEIDEFSAAGFIGVRDDDGKTTIVVPDSSCIIQSVTSDSCVQLARSYGWSVEVRPIKYTELPEFSEVLAVGTAAVIVPIGSITRDSLRDLIVYKPSEDGGYPCADKLFKSIKDIQRGLGKDVFNWCVPVHEPGAYFQPVSA
What is the function of this protein?
Aminotransferase; part of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety (PubMed:28365998).  The first step of the pathway is provided by the HR-PKS poxF that serves in a new mode of collaborative biosynthesis with the PKS-NRPS poxE, by providing the olefin containing amino acid substrate via the synthesis of an ACP-bound dec-4-enoate (PubMed:28365998).  The cytochrome P450 monooxygenase poxM-catalyzed oxidation at the alpha-position creates the enzyme-bound 2-hydroxydec-4-enoyl-ACP thioester, which may be prone to spontaneous hydrolysis to yield 2-hydroxydec-4-enoic acid due to increased electrophilicity of the carbonyl (PubMed:28365998).  2-hydroxydec-4-enoic acid can then be further oxidized by poxM to yield the alpha-ketoacid 2-oxodec-4-enoicacid, which is reductively aminated by the aminotransferase poxL to yield (S,E)-2-aminodec-4-enoic acid (PubMed:28365998).  The Hybrid PKS-NRPS synthetase poxE then performs condensation between the octaketide product of its PKS modules and the amino group of (S,E)-2-aminodec-4-enoic acid which is activated and incorporated by the adenylation domain (PubMed:28365998).  The resulting aminoacyl product can be cyclized by the Diels-Alderase PoxQ and reductively released by the reductive (R) domain of poxE to yield an aldehyde intermediate (PubMed:28365998) (Probable).  The released aldehyde is then substrate for a Knoevenagel condensation by the hydrolyase poxO followed by an oxidation at the 5-position of the pyrrolidone ring (PubMed:28365998).  The presence of the olefin from the amino acid building block allows for migration of the substituted allyl group to occur (PubMed:28365998).  This allylic transposition reaction takes place in a conjugate addition, semipinacol-like fashion to yield a succinimide intermediate (PubMed:28365998).  Iterative two-electron oxidations of the C7 methyl of the succinimide intermediate to the carboxylic acid can be catalyzed by one of two remaining cytochrome P450 monooxygenasess poxC or poxD to yield oxaleimide A (PubMed:28365998).  Subsequent oxidation yields the maleimide scaffold oxaleimide I (PubMed:28365998).  Both oxaleimide A and oxaleimide I can undergo oxidative modifications in the decalin ring to yield the series of products oxaleimides B to H (PubMed:28365998).
What are the official names of this protein?
Aminotransferase poxL, Oxaleimides biosynthesis cluster protein L.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: HEM3_HYDCU
Sequence: MKKTLRIATRKSPLAMWQAEFVKAELEKHHEGLTVELLPMSTKGDKILDVPLAKIGGKGLFTKELEDRMLAGEADIAVHSMKDVPMVLPEGFALGAILERHEPTDAFVSNDYAHFEELPQGAVLGTSSLRRKAQLMAARPDLVVKDLRGNVGTRLGKLDAGDYDAIVLATSGLKRLELDERIRHELSPETCLPAVSQGTLGIEYFEKDPEVLELIQVLNHRDTEIRTLAERAMNHRLEGGCQVPIGVYAELEDDQIYLRGLVGALDGSEILRSEARGSQKDPETLGVYVAEQLLEQGAGEILKEVYDQA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: NAGB_CALS4
Sequence: MKVMIVRDYDEMSRRAAEIVKEQILKKPDTVLGLATGSTPLGMYKYLIEMHKNGEIDFSNVITFNLDEYIGLSPDHPQSYHYFMYENLFNHINIKKENIHIPNGVAEDLEEECKRYEREIRRIGRIDLQILGIGVNGHIGFNEPDESIETKTHIVTLTEETINANKRFFKSIEEVPRRAITMGLSSIMKARKIMLLASGSNKAKAIKETLKGRLTTKVPSTVLALHPDVTIIIDKRAASLLTDEELANVELID
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: MIAB_CHLPB
Sequence: MNSIIKGNVLQMTKKVYIRTFGCQMNQADTEIITALLQDEGYVMTGSEERADLVILNTCAVRENAVEKILHTLDHMKGKRRSRPGLLVGVIGCVPQYYREKMFGMADGIDFLAGPDTYRQLPAMIANAGQGIRGADFGFSSDETYCGIEPARSGTISAFIPVMRGCNNRCAFCVVPFTRGKERSRPFRSVLEDVGRLAASGYKEITLLGQNVNSYSDDEAACDFTELLDRVAVAAEGVRIRFTTSHPKDISESLVRVIAARNNICNAIHLPVQSGSTRMLKLMNRGHTREEYFEKIAMIRSAIPGVTVSTDLIAGFCGETLEDHQATLSMMEDVRFDFAYMFYYSVRPGTYAAKHLPDDVPEEEKKRRLEEIIALQGSISGERNAAEVGAVVEVLAESESKRSSEMLMGRTDTNRVVVFDRHGFEAGDLVKVRIRSSTPATLIGTPA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_TRICV
Sequence: MSRYRGPKLRITRRLGALPGLTQKQSKKKGRPGQHGKSNEADNSKKTTEYGIRLEEKQKLKFNYGLTESQLYRYIKEARRRKGVTGLILLQLLEMRLDTICFTLGFAPTIASARQLVNHGHITVNDNVVSIPSFQCQINDVIGIKPKATSKNLVEGNLQTIKQVDLPTHLKFDKSKQEATVINYCDRNELLLNLDELLVIEYYSRR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HPPD_DANRE
Sequence: MTSYTDKGEKPERGKFLNFHHIKFWVGNAKQAAVFYCDKFGFEPLAYKGLETGSREVVSHAVRQDKIIFVFESALNPGNEEMGEHMIKHGDGVKDVAFLVEDCDFLVKKAKERGAAVLKEPWVEQDAGGKVKYAIVQTYGDTTHTFVEYLGPYKGLFLPGYKEPLFRDPLLPKLPSGHLSFIDHIVGNQPDDEMVPVSDWYQKCLLFHRFWSIDDKQIHTEYSALRSIVVTNYEETIKMPINEPAMGKKKSQIQEYIDYNGGPGVQHIALNTSNIIQAIVNLRARGLEFLSAPDNYYESLREKLKTAKIKVKEDLKTLQELKILVDFDDKGYLLQIFTKPVQDRPTLFLEVIQRNNHFGFGAGNFKSLFEAIEKDQDARGNLTVLTAQNQSVSKAFQ
What is the function of this protein?
Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
What are the official names of this protein?
4-hydroxyphenylpyruvate dioxygenase, 4-hydroxyphenylpyruvic acid oxidase, 4HPPD, HPD, HPPDase.
What is the protein family that this protein belongs to?
Belongs to the 4HPPD family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Protein: YELL_DROMD
Sequence: MHAQDKGGILPALSLLLIAVAMVSPSQAAYKLQERYSWNQLDFAFPNARLKEQALASGDYIPTNALPVGVEHFGNRLFVTVPRWRDGIPATLTYINMDHSVTGSPELIPYPDWRANTAGDCANSITTAYRIKVDECGRLWVLDTGTVGIGNTTTNPCPYAINIFDLTTNTRIRRYELPAADTNPNTFIANIAVDIGKNCDDAFAYFADELGYGLISYSWELNKSWRFSAHSYFFPDPLRGDFNVAGINFQWGEEGIFGMSLTPIRSDGYRTLYFSPLASHRQFAVSTRILRDETRTEDSYHDFVALDERGPNAHTTSRVMSDDGVELFNLIDQNAVGCWHSSMPYSPQSHGIVDRDDVGLVFPADVKIDENKNVWVLSDRMPVFLLSDLDYSDTNFRIYTAPLATLIENTVCDLRNNAYGPPNTVSIPKQAAPGHSAVGPPLYTTTNQYRSLLSQKPQTSWGPSLPSRNYLPALNGNPGIPGSRNNLNNLGAPGQVVSSVSVSTNTVGPSGIEVPKAYVFNQHNGLNYETSGPHLFPTLQPAPSQLGGGLKTYVNARQSGWWLHQQQG
What is the function of this protein?
Controls the pigmentation pattern of the adult cuticle and larval mouth parts.
What are the official names of this protein?
Protein yellow.
What is the protein family that this protein belongs to?
Belongs to the major royal jelly protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: HBG_ATEPA
Sequence: MSNFTAEDKAAITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGSLSSPSAIMGNPKVKAHGVKVLTSLGEAIKNLDDLKGTFGQLSELHCDKLHVDPENFRLLGNVLVTVLAILHGKEFTPEVQASWQKMVAGVASALASRYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma, Gamma-globin, Hemoglobin gamma chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GPDA_LACLA
Sequence: MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNPEQMAEINEKHTNTRYFKDVVLDEKIKAFDRLDLALEDVDAILFVVPTKVTRLVAKQVAEVLKHKVHILHASKGLEQGTHERISTILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASKDHDEAKYAQAIFSNDYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGEKLADIEKNMGMVIEGVSTTKAAFELAQQLGIDMPITETIYKVLYENLDAKTGILDIMRRETRAENEFINNK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHSP1_MOUSE
Sequence: MSSEPPPPPLQPPTHQTSVGLLDTPRTRDRSPSPLRGNVVPSPLPTRRTRTFSATVRASQGPVYKGVCKCFCRSKGHGFITPADGGPDIFLHISDVEGEYVPVEGDEVTYKMCSIPPKNEKLQAVEVVITHLAPGTKHETWSGHVISN
What is the function of this protein?
Binds mRNA and regulates the stability of target mRNA.
What are the official names of this protein?
Calcium-regulated heat stable protein 1, Calcium-regulated heat-stable protein of 24 kDa, CRHSP-24.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule. Note=Detected at cytoplasmic stress granules and P-bodies. Detected at exosome granules where mRNA is degraded.
Protein: TX32D_CHIGU
Sequence: MNHCFLILFTLIVFTVVWSLEENEEYPDEDEMIESFMDGYSYRGDDGTCILKGDHCHGTCDCCGWTTTCRKSKSAGGKICKSEGSSISAFNAIAKGVAAMKKAKCKHKSG
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U32-theraphotoxin-Cg1a, U32-TRTX-Cg1a, Jingzhaotoxin-66, JZTX-66, Peptide F8-12.07.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NRARP_XENTR
Sequence: MSQAEMSTCSTPHTQRVFQEAVRKGNTKELQSLLQNMTNCEFNVNSFGPEGQTALHQSVIDGNLELVKLLVKFGADIRLANRDGWSALHIAAYGGHQDIVLYLITKAKYSSSSR
What is the function of this protein?
Promotes loss of intracellular domain (ICD) of Notch1 in embryos.  By down-regulating ICD levels, could function as a negative feedback regulator of Notch signaling that attenuates ICD-mediated transcription (By similarity).  Involved in angiogenesis.  May be involved in somitogenesis (By similarity).
What are the official names of this protein?
Notch-regulated ankyrin repeat-containing protein.
What is the protein family that this protein belongs to?
Belongs to the NRARP family.
Protein: SYFA_LEGPA
Sequence: MLVLINTIQEQASEAIKQATDIVALEQIRVDFLGKKGKLTELLKGLANLSAEEKPKVGQLVNQAKQGISALIETKMIELKEKQLLAKLAAEQIDVTLPGRNHSTGSLHPVTQVKHRINDYFSRLGFDIVEGPEIETEFYNFEALNIPGHHPARAMHDTFYFGDGRLLRTHTSPVQIRTMEQRKPPFRLIAPGRVYRCDSDVTHTPMFHQVEGLLIDKQATLAGLKGLLQDFFAYFFGRELALRFRPSYFPFTEPSAEVDIECTQCNGKGCRSCKFTGWLEVLGCGMVHPNVLIAVNIDPNEYHGWAFGMGMDRLAMLYYGIDDLRMLFENDLTFLRQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_NITOC
Sequence: MDEHYQAIQIEAEAQAYWEQHQSFRASEDPSKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRMRGRNVLQPMGWDAFGLPAENAAIQNRVPPAQWTYENIDHMRRQLKRLGFAYDWSRELATCQPDYYRWEQWLFTKLFAKGLVYKKTALVNWDPVDQTVLANEQVIDGRGWRSGALVERREIPQWFLKITAYGEELLTALDGLTGWPEQVRAMQRNWIGRSEGIEVQFHVEGKEALAVFTTRPDTLMGVTFVSVAAEHPLAREAATSNPALAAFLEQCQRTATSEAILETLEKEGMDTGFKAIHPITGEAVPIWVANFVLMGYGTGAVMAVPAHDQRDYEFAKVYGLPIQQVIAPKDDQASCNLEQSAFVEKGLLINSGDFTGLDFDQAFAAIAEHLERGGKGQRRVNYRLRDWGVSRQRYWGAPIPIVHCLHCGAIPVPEEDLPVVLPERVRFDGIRSPLKQLPEFYQTSCPQCGGQAKRETDTFDTFFESSWYYARYCCPDNNATMVDERGDYWLPVDQYIGGIEHAVLHLLYARFFHKVMRDMGLVRSDEPFTHLLTQGMVLKDGAKMSKSKGNTVDPQALIEHYGADTARLFIMFAAPPEQSLEWSESGVEGAHRFLKRLWRIVAAHVEQDPKAALTLKVKDLNSEQKSFRAKVHETIAKASDDIGRRYTFNTAIAAIMELMNALAKFDDSSPQGQAIRQEALEAVVLLLSPITPHICHRLWQELGHREAIIGVPWPEADPDALAKESIELVVQVNGKRRGQITVAVQAPREEIEGQAQAEPNVQRFIEGKTVQKVIIVPNRLVNLVVS
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PE09_MYCTU
Sequence: MSYMIATPAALTAAATDIDGIGSAVSVANAAAVAATTGVLAAGGDEVLAAIARLFNANAEEYHALSAQVAAFQTLFVRTLTGGCGVFRRRRGRQCVTAAEHRAAGAGRRQRRRRSGDGQWRLRQQRHFGCGGQPEFRQHSEHRR
What is the function of this protein?
Together with PE10, induces macrophage apoptosis through human Toll-like receptor 4 (TLR4) signaling pathway.  Interaction with TLR4 leads to increased levels of phospho-IRF-3, increase in the transcript levels of IFN-beta and pro-apoptotic genes, up-regulation of IL-10, down-regulation of IL-1b and enhanced levels of macrophage apoptosis.
What are the official names of this protein?
PE family protein PE9.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell surface.
Protein: VSP5_CROAD
Sequence: MVLIRVLANLLILQLSYAQKSSELVVGGDECNINEHRSLVAIFNSTEFFCSGTLINQEWVVTAAHCDSTNFKMKLGVHSKKVPNEDEQTRNPKEKFFCPNKKKDDVLDKDIMLIKLDSPVSNSEHIAPLSLPSSPPSVGSVCHIMGWGSITPIEKTLPDVPYCANINLLDDAVCRPPYPELPATSRTLCAGILEGGKDTCVVDSGGPLICNGQFQGIVFYGAHPCGQALKPGVYTKVFDYNDWIQSIIAGNTAATCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine proteinase 5, SVSP, Serine proteinase 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FETP_BURCM
Sequence: MARMIQCAKLGKEAEALDFPPLPGELGKRIYESVSKEAWQGWLKQQTMLINENRLNMADPRARQYLMKQTEKYFFGDGADQASGFVPPTEG
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: PRND_MOUSE
Sequence: MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK
What is the function of this protein?
Required for normal acrosome reaction and for normal male fertility (PubMed:12110578, PubMed:15161660, PubMed:15007175).  Can bind Cu(2+) (By similarity).
What are the official names of this protein?
Prion-like protein doppel, Doppelganger, Dpl, PrPLP.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: GLMU_LACLS
Sequence: MNKFAIVLAAGKGTRMKSALPKVLHQVAGKSMLAHVLKSVSEVEIAKNVVIVGHEADRVIATLPKGTQFVKQVEQLGTGHAVRIAADLLANEEGATLVIAGDTPLITGETLGALFDYHFAQKATATILTAIAPNPTGYGRIIRDEKGSVEKIVEQKDANDFEKSITEINTGTYIFDNKSLFKALTEITTDNAQGEYYLTDVIEIFKKAGQTIAAHILDDFDESLGVNDRVALSQAEGTMRKRINHEHMVNGVTLIDPATTYIDSEVTIGAETVIEANVTIKGNTFIGKNVLITNGSRIENSEIHSNCEVRNSTVEESRMSVGSNVGPYAHLRPGTVLSEEVHVGNFVEIKGSTLGKGTKAGHLTYIGNATVGEKVNFGAGTITANFDGKNKFNTEIDDFAFIGSNSTIIAPLHIGKNALTAAGSVVTEDVPDEAVEIGRGKQVNKLGRAKKMPHYRGQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP83_DROME
Sequence: MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAGDAPSLVEDTEDASHMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.  Together with Hop and piwi, mediates canalization, also known as developmental robustness, likely via epigenetic silencing of existing genetic variants and suppression of transposon-induced new genetic variation.  Required for piRNA biogenesis by facilitating loading of piRNAs into PIWI proteins.
What are the official names of this protein?
Heat shock protein 83, HSP 82.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_LIMRJ
Sequence: MANPIVAVVGRPNVGKSTLFNRIAGERISIVEDTPGVTRDRIYAHAEWLGKHFSMIDTGGIEISDQPLLTQIRQQAEIAIDEADVIIFVADVENGVTDADEQVARILYRSNKPVVLAVNKVDNPERRSDIYDYYSLGLGEPYAVSSVHGIGMGDLLDAVIKEFPDNAANDEDDSIHFSFIGRPNVGKSSLVNAILGENRVIVSNVAGTTRDAINTQFETADGQKFTMVDTAGIRKKGKIYENTERYSLMRSMRAIDDSDVVLVVLNAEEGIRELDKHIAGYAHEAGCGVIIVVNKWDTLKEKDHRTMTDFTNLIRQEFQYLSYAPIIFVSAKTKQRLNQLPGLIEEVYQHHRQRIQSAVLNDVLMDAIAANPTPTQNGRRLRVYYGTQVATEPPTFVIFVNDPELMHFSYERYLENQIRKAFDFSGTPIHLIKRQRQ
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL1_CHLTR
Sequence: MTKHGKRIRGIQETYDLAKSYSLGEAIDILKQCPTVRFDQTVDVSVKLGIDPRKSDQQIRGSVSLPHGTGKVLRILVFAAGDKAAEAIEAGADFVGSDDLVEKIKGGWVDFDVAVATPDMMREVGKLGKVLGPRNLMPTPKAGTVTTDVVKTVAELRKGKIEFKADRAGVCNVGVAKLSFDSAQIKENVEALCAALVKAKPATAKGQYLVNFTISSTMGPGVTVDTRELIAL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PSBC_VITVI
Sequence: MKTLYSLRRFYPVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRALVWSGEAYLSYSLGALAVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FKBY_HAEIN
Sequence: MLKIQKLSIAALMVSAVISGQVFAEDNTFDEKAASYAVGTLMGSQMKDLVDSHKEVIKYDNARILDGLKDALEGKVDVRKDEKIQKTLESIEAKLVAASKAKAESIAKQAKEEGDKFRAEFAKGKDVKTTQSGLMYKIESAGKGDTIKSTDTVKVHYTGKLPNGKVFDSSVERGQPVEFQLDQVIKGWTEGLQLVKKGGKIQFVIAPELGYGEQGAGASIPPNSTLIFDVEVLDVNPKSEK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Probable FKBP-type peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.