PharMolix/UniProtQA huggingface dataset:
Protein: NFE4_HUMAN
Sequence: MPRVVCWHTLKSLNGYKNLSSGAETREGLRSSSPVDLPLRPRKQATAAGQRKLLSLQLLLCACTSVTDLTYWGPAGHGATAPHRSLLAIHLHLVPASSAAMKATGPHNAQTQVNPQGHAPSAEDPTGTWTVSGPCKDHPHPFLSQSNPPTRISSALPLKTDSALEQTPQQLPSLHLSQG
What is the function of this protein?
Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR).  The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter.  In contrast, isoform 2 acts as a repressor of gamma-globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
What are the official names of this protein?
Transcription factor NF-E4.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS17_CLOP1
Sequence: MERNLRKKRLGRVVSDKMDKTIVVAVETKVRHPLYGKTVNRTTKFKAHDENNEARFGDRVLIMETRPLSKDKRWRLVEIVEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: IF1C_VITVI
Sequence: MKEQKWIHEGLITESLPNGMFRVRLDNENMILGYVSGRIRRSFIRILPGDRVKIEVSRYDSTKGRIIYRIRNKDSNN
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MATK_FROFL
Sequence: MEEFQGHRELYRSWQHNFFYPLIFQEYIYTFAYDRGLNKLILLENVVDQRYSLLTVKRLITRLYHQNHLILSVNDSNQNEIFGHKPKKNLYSQMITEGFAVIVEIPFSLLLISSLDGKEKKIGKSTNLQSIHSIFPFLEDKFLYLNYVLDILIPYPTHLEILVQTLRYWLKDASSLHLLRFFLYECRNWTSRITSKESISFLKKRNRRLFLFLYNFYVCEYEYFFVSLRNQSSYLRSTSFGALLERIHFYGKFKYLVKVKDFAVILWFFKEPFPHYVRYQGKALLASKGTSLLMHKWKYYFIYFWQCYFSVWSQPRRIYINQLSNYSLDFMGFLSNVRFNSSVIRSQMLENSFLLENIRKKFDTIVPISPLVGSLAKAKFCNVLGHPIGKSVWTDLSDSDIIDRFGRICRNLSHYYSGSSRKKNLYRIKYILRLSCARTLSRKHKSTVRAFLKRLGSEFLEEFFTEEEKVLSLILPRDSSTSGGLYRGRVWYLDIICIHNLVNDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FPG_BRUME
Sequence: MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRPGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: AROE_SINFN
Sequence: MRDSRETFVNHAFVTGYPIKHSRSPLIHGYWLKQFGIAGSYRAHEVTPEAFPEFMGQLRDGGTGFCGGNVTIPHKEMAFELSDRPDELSAELGAANTLWLEDGRICATNTDGRGFVANLDERASGWDRISTAVILGAGGASRAVIQAVRDRGVKTIHVVNRTAARAQELADRFGRAVHAHPIAALSEVMAGAGLFVNTTSLGMDGEPAPAIDFSPLANGAVVTDIVYVPLKTPLLRQAEEQGYRIVDGLGMLLHQAAPGFEKWFGLRPVVDETLRQIIIKDMDVHA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NUOK_RUTMC
Sequence: MVSLSDYLILSSVIFCIGLVGIFVNRTNIITLLMCVELILVAVNTNFVAFSHFLGNEVGQIFVFFILTVAAAEVAIGLAILTLLFRNRGSISVDVTNSLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDHI_MARPO
Sequence: MFSIINGLKNYNQQAIQAARYIGQGFLVTLDHMNRLPTTIQYPYEKLIPSERFRGRIHFEFDKCIACEVCVRVCPINLPVVDWELKKTIKKKQLKNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYNRHELNYDQIALGRLPISIIEDSTIENIFNLTSLPKGKIEGHIYSRNITNIVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: QOX2_BACCR
Sequence: MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIVFILFTVILIRYREKPENMDYEPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEVPKESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPAGVPIQFKLTSVGPMNAFWVPELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEVQETAPKLTEAKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.  Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.
What are the official names of this protein?
Quinol oxidase subunit 2, Cytochrome aa(3) subunit 2, Quinol oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ESC2_YEAST
Sequence: MTGDSRSISEPSINLDPDNTSFSDENSDDFFMDNSYDIDEIDHSDESNRQSVIVDSKVTVPPSKHSTLTLSDSEDSDAKEQHQSLSRSSSKNVNIEDITEPKPDKPSGRTRGRSVMKESVVEINSSESDLDEDKNFPRSRSRSRSSIRSISPAGKYKRQKSSLLYTYDENDDFFKELAKEAKKSTTISKESTPDQRKRVYNIKFLSKLEGTINKAVQVKVLGKYEFSKILPAALDGLMKSYKIPKVMKDIYKVENVTLYWNNAKLLTFMTCNSLHIPQDFENEVSDIDVTIVSKEYEKNFEATLESKLKEEEAALLIKERQEMERKLEKKRNEQEESEYREFESELKNVEETQEIKENDTVMNTKLLQEGGSLSGNSSSMEEVMRIALMGQDNKKIYVHVRRSTPFSKIAEYYRIQKQLPQKTRVKLLFDHDELDMNECIADQDMEDEDMVDVIID
What is the function of this protein?
May be a substrate targeting component of a cullin-RING-based E3 ubiquitin-protein ligase complex RTT101(MMS1-ESC2).  Involved in HMR and telomere silencing via the recruitment or stabilizing of the SIR (silent information regulators) complex.
What are the official names of this protein?
Protein ESC2, Establishes silent chromatin protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FLIDL_VIBPA
Sequence: MSSIDPATFAAQFAQIEIQPFKQRYQLQTNTYQSQLSALGKVESAMREFRTALNEMNSSTNSIIKNSTSISQEGYFTANADAKALSGSYQIFVEQVATSHQVSTGMPADLDATTEIPKTGNLEFTINGKTMTIDLSTVDTDGDGVTTVSDLTKAINNNSDNPGVNATLVRSNGQTHFMLSSTETGVANQINVSATGTGQAWFEDAFTNLSQISAPQDAVIWLGAEKTGLKLTNSSNTFEGVIDGVDITVTKAQTSGETAIGLGIGADDEATKEQLNKFVDAYNTLISTIDEHTQIGSEDKKRGVLASDPTMRSIESQLSSLVRGEHGGMRLSEIGVTLDRHGKLKVDQEKFAEAQKNNSAGLEAMFNGDGALLDSMDAMAEPFLKFSSGAFKSRKEALQANLDRLSDKQTTLERKYDMSYKRYLKQFTQMNTLMTQMNQTMSMFG
What is the function of this protein?
Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament.  Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.  Essential for swarming motility.
What are the official names of this protein?
Lateral flagellar hook-associated protein 2, HAP2, Filament CAP protein, Flagellar cap protein.
What is the protein family that this protein belongs to?
Belongs to the FliD family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RNH3_PHYMT
Sequence: MKNYSFTFDIPQLRKLKKIYKSFLIEKEINNNSIYFFLKKDNIQMIAYNNGTFFIKGENIQEEILNIKEILNIKDYSAIGSDEVGTGDVFGSIVVCSSYVSAENIPFLENLNIKDSKKLTDEKIIQLVPKIINKITYSLISINPYKYNILTNKGFNLNKIKAILHNDMILKNLIKIKKNVNVILDKFTSSKNYFNYLKNEKKVYKKIFFCNKAEKVHISVAAASIIARYAFLKNIFALSKKIGINLKLGASTEVDKQINFIYKKYGMNILKKIAKCNFKNITKQFIKN
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_ALKCK
Sequence: MHEFVTICIMAAALGMDAFSVALGMGMLKLSGKQIFRIGLTIGLFHVAMPLAGMAVGKWLSGHFDVIATYIGGGLLLVIGVQMALNAFSDHEAEGLKPAGWGLLLFAVGVSLDSFSAGLSFGILGTEMFVTVGMIGAMSMVMSWIGLIVGSHFQKFLGAYGELLGGLVLIGFGLKIMLPL
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YPP1_YEAST
Sequence: MPNSNVRIPPTVPSKIIDVVDQALRARLLGGSTFNSGFDSLDSVLNLQFRLHYHVIGSNGPAKPVCDVLLKESQNLEKNMSMMEELNDYPEITKLVEKILFNCLGILFFHRGQFQESQRCLLHSLKIHNNTASQKTALMEQYDRYLIVENLYYRGLVSQDINIMQNVFYKELLAHVDTIPPESNGLLFEYISLIVAKLRFNQIQDLAENFKTTVENPFILFLYMIKKFQSPLKKHIDNDDLYLKFGQNVLLKAKFPTASETNDEALEHFNVFLQYYFKFTHIKKIKVNPSWYNFIISSMEKTFQSIEVSKTAMFLFQNLSDNSNDEIKKKTFKRESILNFVNFVKYNDKYYQLHDNSHRDIISFIDAYSFILQNSSKTDSIENVFDYDNTVSTFATSLNSFYKEYNLPLMSQSESLDWLENSTRCVYPGNISKVLTNAWSTLYEIRKYQLDFLVSNNLTSYLCNAMMLSTKEKDNADVEEQEEGEEEKALRELQFKYSYTLAQQRHIETAIKTLESLILSKNPNYYKAWHLLALCRSVQEDKEMSYKIVCSVLEAMNESLQNNTLLLNDRWQFIHLKLTQLALIEEIFGTLEALETLPEVFELYATLFPDSQPELNSMGPKYSQTKEYLLQMVWIFAANMYMRTKDNDEDAKAAIKEASNVESKFKNLNCNIANGYLSIIKDEPGVALKEFETVLYYDENNLDALVGFAELIFPEELGVEETNLERYYTLSLDKKPGKRAKLTFVNDTDRSAAYARLKFLLECAILESIEAYYSPEVWWYLSLIYEKYQDDEYKNSLLKCIKYQELNPIRSLRYCNY
What is the function of this protein?
Involved in endocytosis.
What are the official names of this protein?
Cargo-transport protein YPP1, Alpha-synuclein protective protein 1.
What is the protein family that this protein belongs to?
Belongs to the YPP1 family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPOC_PEDAC
Sequence: MIDVNKFESMQIGLASPDKIRMWSYGEVKKPETINYRTLKPEKDGLFDERIFGPTKDYECACGKYKRIRYKGIVCDRCGVEVTKSKVRRERMGHIELAAPVTHIWYFKGIPSRMGLVLDMSPRSLEEIIYFASYVVVDPGDTPLEKKQLLTEREYRAKLDEYGNRFVAKIGGEAIQALLQSVDLEKEANLLKEELKEASGQKRTRAVRRLDIIEAFIKSGNHPDWMVMDAIPVMPPDLRPMVQLDGGRFATSDLKHLYRRVINRNNRLKRLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVAGPGNRPLKSLSHMLKGKQEGFRQNLLGKRVDYSGRSVIDVGPSLKMNQMGLPVPMAMELFKPFIMKELVSRNLASNIKNAKRKIDRKDEEVYDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVSGKAMRLHPLACEAYNADFDGDQMAIHVPLSNEAQAEARLLMLAAHHILAPKDGKPVVTPSQDMVIGNYWLTMERAESVGEGMIFNDLDEVKLALQNGYVSIHTRIGVRASSMPEKPFTDQQRQQILITTAGKMLFNDILPKDFVYLNAPTNEKLVNGTPDEYFLEAGEDIHEQLNQRPLLSPFKSGFLSDVIAEVYKQYKVTETSLLLDRMKDLGFYRSTLSGLTVGIADITNLPDKPAIIAAAHKKVATVTKQFRRGLITDDERYERVIGIWNDAKDEIQQRLMDTFDPQNPIFMMSDSGARGNISNFTQLAGMRGLMAAPNGKIMELPILSNFREGLSVLEMFISTHGARKGMTDTALKTANSGYLTRRLVDVAQDVIVREKDCGTDRGLLITAIAEGNEMIEPLYDRILGRYTMKSVINPETGKVIVGQNEMIDERSAQEIIDAGIQEVTIRSAFTCNTAHGVCEKCYGRNMATGDRVEVGEAVGTVAAQSIGEPGTQLTMRNFHTGGVAGNADITQGLPRIQEIVEARNPKGPAEISEVTGVVESIEEDPAEGTKEVTVKGETDSRTYSLPITARMKVAEGDYIHRGAPLNEGSIDPKKLIKVRDVLSTENYLLSEIQK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RLMH_METPP
Sequence: MKLALVAVGQRLPAWAETACEDYLKRFPADWRVELKAVKAEPRTQGKTVDAMKAAEAQRIEAACARGVRRVVLDERGTRLTTQQLAQRLQAWQLDGRDVALLIGGPDGLADTLKDGADETLRLSDLTLPHAFARVLLAEALYRAWSVNAGHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_RICTY
Sequence: MKKSVNLLSGGIDSATVLAIASEMCYEIHAMSFNYGQRNHAELQKVKELIKKYNVKQHKIVDIDLRAFGGSALTDDNIDIPHYHSINELPEIVPVTYVPARNTIFLSYALGFAEVIGAQDIFIGVHTSDSANYPDCRPEYIKSFEKMVNVATNMGIQGKKITIHAPLIDMTKEQIIRTGLKLGVDYKNTISCYTPTEDDLSCGNCLACIIRLDAFKKNNIQDPIKYV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: HRCA_STACT
Sequence: MITNRQQSILNAIVEDYVDYGLPVGSKTVIERHQVNVSPATIRNEMKILEGMGLIEKAHASSGRSPSIKGFRYYVDQLLENTSPRTEFNNQRLNKLLADYNYNLSNALSVYANELSMSTKYTTLIMKPNQSKDLITDVHLFNTVAHLVIMVIVFESGNVEHLQLAVPEKISKNRLVQIANYIKSIFNADMRNDFSDETFMHSNDYLIVNQLIDLLNQRLNDITTDIFFGGKANLIDTLNEQNVNSIQQILQYLESNKILKLFEDDNHSGIDVKIGQEIDNGLEDISIILSDYHIDNHLKGHVAVIGPTAMRYQNVIQLLYKV
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: YOEF_ECOLI
Sequence: MAGVRQHGWRAIPAVCSEYGADTLPDRYRSDGRCLLFWQQAGISALKQELEVKTPYRAMNHPVIGVVTKADLASMEQISLVKSWLREAGAHNVLVTSAVNNNGVTELFALLHTEEGCC
What are the official names of this protein?
Protein YoeF.
Protein: ZEB1_MESAU
Sequence: MPEDELPADQTVLPGGSDREGGAKNCWQDDVKDDECDSDAENEQNHDPNVEEFLQQQDTAIIYPEAPEEDQRQGTPEASGQDENGAADAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFSCSLCSYTFAYRTQLERHMTSHKSGREQRHVTQSGGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLMPVNGRPRSGLKTSQCPSPSLSASPGSPTRPQIRQKIENKPLQEPLSVNQIKTEPVDYEFKPIVVASGINCSTPLQNGVFSGGGQLQATSSPQGVVQAVVLPTVGLVSPISINLSDIQNVLKVALDGNVIRQVLENNQASLASKEQEAVNASSIQQGGHSVISAISLPLVDQDGTTKIIINYSLEQPSQLQVVPQNLKIENPAPTNSCKSEKLPEDLTVKSEKDKGFDGAVDGSTCLLYDDCPGDLNALPELKKHYDPEHPAQPPPPAPEAEKPEASASSARDGDLSPSQPPLKNLLSLLKAYYALNAQPNSEELSKIADSVNLPLDVVKKWFEKMQAGQIPGQSPEPPSPETGTVNIPAKSDEQPQPADGSEPQEDSASGQSPLKMTSSPVLPVGSAINGSRSCTSPPSPLNLSSARSLQGYFCVADGAQEEPQVEPLDLSLPKQQGELLERSTISSVYQNSVYSVQEEPLNLSCVKKEPQEDSCVTDSEPVVNVIPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYATTVSPAMQEPPVKVIQPNGNQDERQDTSSEGVSTVEDQNDSDSTPPKKKTRKTENGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICKKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEERDGTEQEQEEAGLEALMNEHVGARASPSQADSDERESLTREEDEDSEKEEEEEEDKEMEELQEEKECGNAQAEEEEEEEEEEMDGAKDEAAAKTDGAVENGAAPQAGSLEQKASESSEQLSEETTNEA
What is the function of this protein?
Acts as a transcriptional repressor.  Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes.  Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1.  Represses BCL6 transcription in the presence of the corepressor CTBP1.  Positively regulates neuronal differentiation.  Represses RCOR1 transcription activation during neurogenesis.  Represses transcription by binding to the E box (5'-CANNTG-3').  Promotes tumorigenicity by repressing stemness-inhibiting microRNAs (By similarity).
What are the official names of this protein?
Zinc finger E-box-binding homeobox 1, Transcription factor 8, TCF-8, Zinc finger protein BZP.
What is the protein family that this protein belongs to?
Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APNO_BLAHS
Sequence: MGKIVVSVIGAGGKMGTRTSNNLAKKPEEFDLLLVEASEAGIQSIKDRGFEPTPVEEALEKSDVVVFAVPDTLIGKLSAIYVPQLKPGTGFIILDPAAAVARELTLRDDCTFGVAHPCHPSYFLDQDTYEARQDRFGGCGGKQDIVMSKIQGNDDRFAQCVEVAKQMYAPVEHAYVMSSEQIAFLEPTLVELLGATCLYAMAETVDEAVKRGIPKEAAVSFLTGHIYNLSANFLGYIPGNPPVSDACKVAIGLGNRLVMREDWKKIWDDEVLNKVIATMLHPDKPQI
What is the function of this protein?
Involved in catabolism of D-apiose.  Catalyzes the conversion of D-apionate to 3-oxo-isoapionate.
What are the official names of this protein?
D-apionate oxidoisomerase.
What is the protein family that this protein belongs to?
Belongs to the ApnO family.
Protein: HIS8_BACCN
Sequence: MKVKEQLFSLNAYVPGKNIEEVKREYGLSKIVKLASNENPFGCSKRVKEALALLNEQYALYPDGAAFELRQKVANHLKVQPEQLLFGSGLDEVIQMISRALLHKGTNVVMARPTFSQYRHHAIIEGAEVREVPLKDGIHDLDAMLEQVDYNTRIVWVCNPNNPTGTYVEKQKLLSFLENVPKSSLVIMDEAYYEYAGAEDYPQTLPLLEKYENLMVLRTFSKAYGLAAFRIGYAVGYAELIKKLEVARLPFNTSTVAQVVASVAIDDQSFLQECVKKNAEGLEQYYQFCKEYDVFYYPSQTNFIFLKIGLPGNEVFERLMKKGYIVRSGAPFGLLDGIRITVGLKEENAEIIALLANLVKEHVKKEETYS
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: HEMT_SIPCU
Sequence: GFPVPDPFIWDASFKTFYDDLDNQHKQLFQAILTQGNVGGATAGDNAYACLVAHFLFEEAAMQVAKYGGYGAHKAAHEEFLGKVKGGSADAAYCKDWLTQHIKTIDFKYKGKL
What is the function of this protein?
Hemerythrin is a respiratory protein in blood cells of certain marine worms.  The oxygen-binding site in each chain contains two iron atoms.
What are the official names of this protein?
Hemerythrin.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: G6PI_ECOLC
Sequence: MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETFA_CLOAB
Sequence: MNKADYKGVWVFAEQRDGELQKVSLELLGKGKEMAEKLGVELTAVLLGHNTEKMSKDLLSHGADKVLAADNELLAHFSTDGYAKVICDLVNERKPEILFIGATFIGRDLGPRIAARLSTGLTADCTSLDIDVENRDLLATRPAFGGNLIATIVCSDHRPQMATVRPGVFEKLPVNDANVSDDKIEKVAIKLTASDIRTKVSKVVKLAKDIADIGEAKVLVAGGRGVGSKENFEKLEELASLLGGTIAASRAAIEKEWVDKDLQVGQTGKTVRPTLYIACGISGAIQHLAGMQDSDYIIAINKDVEAPIMKVADLAIVGDVNKVVPELIAQVKAANN
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases.  It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, Alpha-ETF, Electron transfer flavoprotein large subunit, ETFLS.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: PYRE_METAR
Sequence: MDTELVEMLKQTGAVKFGDFTLSSGRKSTYYVDKYIFETNPVCLSVIGDRIAKLIPAGTRRLAGIEIGSIPLAAVASVKSGMPFVVVRKATKGYGTNKLIEGVWQKGEKVFVVEDVVTTARGALGAIHTLREAGLAVDEMVCVVDREEGGRESLEQEGVKVRSLVKSSELLGYKP
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: NU2C1_SOLBU
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVLIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDSLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.