PharMolix/UniProtQA huggingface dataset:
Protein: Y1558_BURCH
Sequence: MDIAHDLQSIGAQEQALVFPHFDPARAWALGNRMHALATSRGHAIAIDIVTFGQPLFYAALAGATPDNADWVRRKRNVVAHFRRSSYAIGLRMQQAGATLADKHGLPVAEYASHGGSFPLTVAGAGVIGSITASGLPQRADHEFVVEALCAELGHDYAVLALARS
What are the official names of this protein?
UPF0303 protein Bcen2424_1558.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: CXCR5_MOUSE
Sequence: MNYPLTLDMGSITYNMDDLYKELAFYSNSTEIPLQDSNFCSTVEGPLLTSFKAVFMPVAYSLIFLLGMMGNILVLVILERHRHTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKINFYCSSLLLACIAVDRYLAIVHAVHAYRRRRLLSIHITCTAIWLAGFLFALPELLFAKVGQPHNNDSLPQCTFSQENEAETRAWFTSRFLYHIGGFLLPMLVMGWCYVGVVHRLLQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLERLKAVNSSCELSGYLSVAITLCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCAGPASLCQLFPNWRKSSLSESENATSLTTF
What is the function of this protein?
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC).  Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes.
What are the official names of this protein?
C-X-C chemokine receptor type 5, CXC-R5, CXCR-5, Burkitt lymphoma receptor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYP_ELUMP
Sequence: MKLTQYYLPTLKEAPKDADTISAKLMLRAGLIRKTASGIYEWLPLGLKVLKKVEQIVREEMDAAGAHEVWLPLIQPKELWEESGRWTYYGKELLRIKDRKGAEFCFAPTAEEVITDVVRRDVTSYKQLPVALYQFASKFRDEIRPRFGVMRAREFYMKDAYSFHATEESINEWYLKFFEAYKKVCTRCGFKFKAVEADTGAIGGNFSHEFMVLADTGENEIADCDCGYAANTEKAEIFKPKFPAAKEELKTIEKVNTPNATTIEDVAKMLGQTADRFIKLLVFTADGQPVVALMRGDHELNEHKLKALLKAQELEKANEETYAKVTGSFVGYAGPVGLKEKNPKIKLFADYHVAGIVNGIAGGNEKDVHIINVTPSRDFTPDVYADLKIASEGDLCGKCGKKFNFTRGIEVGHTFKLGTKYSQSMKAEFLDENQKSHPFLMGCYGIGISRIVAAAIEQSHDENGIIWPAPLAPFDIYLVSIDTDINPKVKEETDSIYNQLTQAGLNVLLDDRNERPGIKFKDADLIGLPHRIVISSRTVETGEYEYKQRTSKEAIRRKLADISEQIKEFQASK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_METVS
Sequence: MVLTNSKQPRKQRKALYNAPLHLRNSVMSAMLSKALKEKYGKNALPVKKGDTVKVLRGSFKGIEGEVSKVNYSGYKIIVEGVVNKKQDGKETPYPIHPSNVMITKMEDSDEKRFKTSNK
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: TRUA_MYCBO
Sequence: MSLTRRPPKSPPQRPPRISGVVRLRLDIAYDGTDFAGWAAQVGQRTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHYVYRLSTAPYGVEPQQARYITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWSRAGTLVTAHVTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLASRNLVTRDVRSG
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ISPF_BUCAP
Sequence: MRIGYGFDIHAFGSIKPLIIGGVQIPYNKGLIAHSNGDLLIHSLIDALLGATAMGDIGTFFPSEDKKYKNINSRILLKYIWKRIYLKNYRISNIDITIITETPKILSYIFLMRSNIASDLNIKIEKISVKSTSSKMIGCIGRKEGIACQSLVMLVKSKNTDRKNNII
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: TATA_SHEAM
Sequence: MGGISIWQLLIIALIVVLLFGTKKLRSLGGDLGGAIKGFKNAMSDEEKKALEDKEAAAQTTQQATEKKPEADKKEQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ENO_HAHCH
Sequence: MAEIVDVRAREVLDSRGNPTVEADVVLKSGVVGSACAPSGASTGSREALELRDKDPARYMGKGVLKAVDAVNTSIRSALIGRDAREQRELDRIMIDLDGTENKANLGANAILAVSLAAAKAAAQEKGVPLYAHIADINGTSGQYSMPVPMMNILNGGEHADNNVDIQEFMVQPVGVASFREALRVGAEIFHNLKKVLHDKGLNTAVGDEGGFAPNLPSNEAALAAIEEAVTKAGYKLGSDVTLALDCASSEFYKDGQYNLSGEGKVFSSEEFADYLGDLSQRYPIVSIEDGMDESDWDGWAALTRKLGDKVQLVGDDLFVTNTKILKQGIDKGIANSILIKFNQIGSLSETLDAIKMAKDAGFTAVISHRSGETEDTTIADLAVATSAGQIKTGSLCRSDRVAKYNRLLRIEEELAGSAPYRGLKEIKGQE
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SOX6_RAT
Sequence: MSSKQATSPFACTVDGEETMTQDLTSREKEEGSDQHPASHLPLHPIMHNKPHSEELPTLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSREREIMNSVTFGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPGDNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINPRLKGISDRLGRNLDPYEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNSAGAVSPTGIKNEKRGTSPVTQVKDETTAQPLNLSSRPKTAEPVKSPTSPTQSLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQPHGVDGKLSSMNSMGLSNCRNEKERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKMDGASLAGNDMINGEDEMEAYDDYEDDPKSDYSSENEAPEPVSAN
What is the function of this protein?
Transcription factor that plays a key role in several developmental processes, including neurogenesis, chondrocytes differentiation and cartilage formation (By similarity).  Specifically binds the 5'-AACAAT-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis (By similarity).  Required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes: SOX5 and SOX6 cooperatively bind with SOX9 on active enhancers and super-enhancers associated with cartilage-specific genes, and thereby potentiate SOX9's ability to transactivate (PubMed:26150426).  Not involved in precartilaginous condensation, the first step in chondrogenesis, during which skeletal progenitors differentiate into prechondrocytes (By similarity).  Together with SOX5, required to form and maintain a pool of highly proliferating chondroblasts between epiphyses and metaphyses, to form columnar chondroblasts, delay chondrocyte prehypertrophy but promote hypertrophy, and to delay terminal differentiation of chondrocytes on contact with ossification fronts (By similarity).  Binds to the proximal promoter region of the myelin protein MPZ gene, and is thereby involved in the differentiation of oligodendroglia in the developing spinal tube (By similarity).  Binds to the gene promoter of MBP and acts as a transcriptional repressor (By similarity).
What are the official names of this protein?
Transcription factor SOX-6.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TRPG_SCHPO
Sequence: MSEKVDVGESVKGDASENAVKEVAERPIVMIDNYDSFTWNVVQYLSNLEKRYPIMVFRNDEITVDELEKLNPLKLVLSPGPGHPARDGGICNEAISRFAGKIPILGVCMGLQCIFETMGGKVDSAGEIIHGKVSKINHDGLGFYQGIPQNISVTRYHSLAGKISSLPDCLDVTSWTENGVIMGARHKKYAIEGVQYHPESILSEYGKEYIQNFLNLTAGTWEENGIVMPTKNNAFNAAMRENSNSVSSTKIRKQESILEKIHAQRLIDIAESKRKPGLSVGDLQTYLNLNIAPPCINFYERLKQSKPALMAEVKRASPSKGDIKLDANAAIQALTYAQVGASVISVLTEPKWFKGSLNDLFVARKAVEHVANRPAILRKDFIIDPYQIMEARLNGADSVLLIVAMLSREQLESLYKFSKSLGMEPLVEVNCAEEMKTAIELGAKVIGVNNRNLHSFEVDLSTTSKLAEMVPDDVILAALSGISSPADVAHYSSQGVSAVLVGESLMRASDPAAFARELLNLSSSEISNGKKTSTPLVKVCGTRSLLAAKTIVESGGDLIGLIFVEKSKRKVDLSVAKEISHFVHTTNRKHISPKKAVTGQSWFDHQYENLASSPHPLLVGVFQNQPLEYIRSIIAEVNLDIVQLHGQEPFEWIHMLDRPVIKVFPLNSSEISRPNYHIVPLIDAYVGGESGGLGKKVDWEAASFIPVSYVLAGGLTPKNVQDAISVSRPAVVDVSSGVETDGKQDLEKIKAFINAVKEL
What is the function of this protein?
Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
What are the official names of this protein?
Multifunctional tryptophan biosynthesis protein.
Protein: FEZF1_XENTR
Sequence: MDSSLQHKTTKIFPSQASRDSLSNRVTMISGAKPLAFSIERIMSRTPEPKCLPVPSLLQGSVPKGDQKQALHINSSSIPCMIPFVPVAYDHCPKIGISGAELRKSHLDSSPPFSCNDLLNCALTLKGDFPREALPLQQYKLVRPRVVNHSSFHAMGAAFCYFNRGDSQCHPPASINIHPVASYFLGSPLHQAPKSYLAERNKLVLPSVEKFSSGVTFKDLSQAQFQHYMKEGAHSLSDKITFKTSAKFSSASPSNKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKICGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQIYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSNTAAPHAIGGTGQEELLLPNREPSPTIQSPQLQKSGY
What is the function of this protein?
Transcription repressor.  Involved in the development of the forebrain region (By similarity).
What are the official names of this protein?
Fez family zinc finger protein 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBS_SPIOL
Sequence: MAQAMLLMMPGVSTTNTIDLKRNALLKLQIQKIKPKSSTSNLFFSPLPSSSSSSSTVFKTLALFKSKAKAPKKVEKPKLKVEDGLFGTSGGIGFTKENELFVGRVAMIGFAASLLGEGITGKGILSQLNLETGIPIYEAEPLLLFFILFTLLGAIGALGDRGRFVDEPTTGLEKAVIPPGKDVRSALGLKTKGPLFGFTKSNELFVGRLAQLGFAFSLIGEIITGKGALAQLNIETGVPINEIEPLVLLNVVFFFIAAINPGTGKFITDDEEED
What is the function of this protein?
Seems to be involved in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.
What are the official names of this protein?
Photosystem II 22 kDa protein, chloroplastic, CP22.
What is the protein family that this protein belongs to?
Belongs to the ELIP/psbS family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein. Note=Extreme lateral location to the appressed thylakoid regions.
Protein: GRPE1_BUCAI
Sequence: MIHNEEEQLEKKIEKNQDPKINHKKYDSDNLIKKNLIQFLEIQLKESEEKIIEKEEIVEKEIVLIHNRFNKEIEKSIKFSLEKIIIDFLPIIDNIERALNLIETINLKQEKYTEILKKLQFICNLLEKFFYLFNIKKINDTNVLFNPSIHQAMSIHYTNDIISNQIVTVMQSGYILHKSRLLRPAMVVVSKEKI
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE 1, HSP-70 cofactor 1.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_ORYSJ
Sequence: MGRKFFVGGNWKCNGTTDQVDKIVKILNEGQIASTDVVEVVVSPPYVFLPVVKSQLRPEIQVAAQNCWVKKGGAFTGEVSAEMLVNLSIPWVILGHSERRSLLGESNEFVGDKVAYALSQGLKVIACVGETLEQRESGSTMDVVAAQTKAISERIKDWTNVVVAYEPVWAIGTGKVATPDQAQEVHDGLRKWLAANVSAEVAESTRIIYGGSVTGANCKELAAKPDVDGFLVGGASLKPEFIDIINSATVKSA
What are the official names of this protein?
Triosephosphate isomerase, cytosolic, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATGT_AERPE
Sequence: MFEIRDVDLAGRIGRIYTQHGVVETPAFFPVIDVYRQEVSVDEVRAAGFGQVITNAYLLWKRFGWEAAEKGVHRILGFPGVVMTDSGAYQILEYGGVELSQGEVVEYQKRLGSDIAVILDIPTGDVGRREAEESVRETIRRALEARVMIEGDERIWVYPVQGGRYFDLVEESARVGGRLGFYRMYGIGSPTVFLERYMYHVVVEAVYRAKKHLPWGRPVHLFGAGHPLIFPYAVALGVDTFDSASYILYAREGRYITEYGVYRIEDLDYLPCSCPVCSRYTPQELREMDRVERTRLLALHNLYVISASMRRVKQAIREGRLWELLEETSRKHPSTARVMARMRRYIDALEKGSARGRGVVRGVRAYGLESLSNPRLSRFSSDAARLVEAMAEKWGGGKAVLKPLDPKPEPGQCESMVGGGEWILFYQPFLGVFPVEACGAYPSLQIDYPQEGLPAEVIGDLASKIASTVSILRGRGFTVRLEYCGKVEWQARAVEALKTAAAGDLPTVEACG
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: PLC_BACCE
Sequence: MSNKKLILKLFICSTIFITFVFALHDKRVVAASSVNELENWSKWMQPIPDSIPLARISIPGTHDSGTFKLQNPIKQVWGMTQEYDFRYQMDHGARIFDIRGRLTDDNTIVLHHGPLYLYVTLHEFINEAKQFLKDNPSETIIMSLKKEYEDMKGAEDSFSSTFEKKYFVDPIFLKTEGNIKLGDARGKIVLLKRYSGSNEPGGYNNFYWPDNETFTTTVNQNANVTVQDKYKVSYDEKVKSIKDTMDETMNNSEDLNHLYINFTSLSSGGTAWNSPYYYASYINPEIANYIKQKNPARVGWVIQDYINEKWSPLLYQEVIRANKSLIKE
What is the function of this protein?
Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates.
What are the official names of this protein?
1-phosphatidylinositol phosphodiesterase, Phosphatidylinositol diacylglycerol-lyase, Phosphatidylinositol-specific phospholipase C, PI-PLC.
What are the subcellular locations of this protein?
Secreted.
Protein: OAT_STAES
Sequence: MTQSEKIINLTNHYGAHNYVPLPIVISEAEGVWVKDPEGNTYMDMLSAYSAVNQGHRHPRIIQALKDQADKVTLVSRAFHSDNLGQWHEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLEGFRKVEFGDVNQLKAAINKNTAAILVEPIQGEAGINVPPEGYLKTIRELCDEHQILFIADEIQAGLGRSGKLFATDWDHVKPDVYILGKALGGGVFPISVVLADNEVLDVFTPGSHGSTFGGNPLASAVSIAAIDVIIDEDLPGRSLELGEYFKSELKKIEHPSIKEVRGRGLFIGIELHESARPYCEALKEQGLLCKETHDTVIRFAPPLVITKEELDMALEKIKSVFA
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCL3_PHANO
Sequence: MRWFGSGDDEKKKKQVGETWADSLRADSWGQSLTNPRTLIPTFAFTITTVTALRLYKTFLRRIPTVNHVKPHYFRRKGIFGKVTTVGDADNFRLYHTPGGRIAGWGWLPWKMVPTKREGLSNQTVGLPCHLGLLSIVSDSPSLVANNFQLHIRLAGVDAPELAHWGREEQPYAKEAQEWLINLIHNRRVRAYIYRRDQYDRIVAQVYVRRWLFRKDVGLEMLKAGLATIYEAKSGAEFGTSEAKYRAAEEKAKAQKVGMWAKPTLLQKLGGASTKAPESPREYKARHAAADKLKKT
What are the official names of this protein?
Probable endonuclease LCL3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: MRPE_ALKPO
Sequence: MAFQILLNLVIAVIWVNFQNSYTAVDFLIGYVVGIFILFVLRRFLRFDFYMRRIWAIIKLISLFFKELILANIDVIKIVLSPKMNIQPGIVAVPTKLKTDWELSLLASLISLTPGTLSMDFSDDNKYIYIHAIDVPNKEKMIRDIHDTFERAILEVTK
What is the function of this protein?
Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit E, Mrp complex subunit E, Multiple resistance and pH homeostasis protein E.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y091_CAUVC
Sequence: MTLKERCVFKLLTCLTTQHDLRLVLVASAVCLAGCFTTFRLYSRMRGARGVVRAAWLLLTGLVAGSSVWATHFIAMVAFTPGLKTGYSPTGTLLSLMIAALFMASGFAVASAQRSTTNDFAGGVLIGLGVAAMHYMGMSAFVTQGQLVWEHATVGMSAVLGVGGATAALLLAGTARTIRRQAVGGGMLCLGIVMLHFTGMSAITIVPDASLTVPDQLLSGGMLTLAVGSITSMIILGGLGAVAIESQTSRSALERIRRLANAAYEGLVVVQSGRINDANAAFCDLVGAPLAELVGRPLFGEILTFDEADPSREDVRREGRLRPLVGGREIPVEVFSRLMDDGARVETSGLTVLAVRDLRERRAAEEKIRYLAEHDGLTGLLNRNSLQMRLAAAIDRVEASGESLAVICIDLDHFKEANDQHGHLAGDALLVETARRLQSAVQAPSFAARLGGDEFIVVQIAGGDQPAVAAELAGRLIEMLAAPVPFDGQELAMGSSLGVSLYPDDGRTAEALMANADMALYRAKESGRGVYRFFKREMDDTIRERRNLARDLRQGIADNELIVHYQPLARAADGEVCGFEALVRWKHPTRGMIPPLDFIPVAEENGLIEALGDWVLRRACADAAAWEKPLRIAVNLSPIQLHNPALPTLVHEVLITTGLSPSRLELEITESALFKDYQRALDNLRRLKALGVRIAMDDFGTGFSSLSTLQSFPFDKIKIDKSFVENIHRHDRATAIVRAVLGLGRSLEIPVVAEGVETEEQILFLRGEDCAELQGYAIGRPAPVDALTMWTTAGDPGAIAPKSKTRRSA
What are the official names of this protein?
Uncharacterized signaling protein CC_0091.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFA_AERPE
Sequence: MEVTLSQGEYRLLKLMAERGFREGTLEEASKILGVDKSSLASLSNLLAEKGVVEVEERVEEHYVLTERGRDALERGLPEEKLVLFLAGRGGEASVEEVRRALGEEAGIALGQAARKGLVVIAGGVVRLAVDQAEALKTITPLKKLLENVASGSKPTVGDELLREALSRGLIRREARRSIVLRLKVNPAEALARARVEAAVLTRDMLKSGEWRRLRFKPYNVKAEPPRVLPARRHFLAEFIERLRDILRELGFREVRGPLVELELFNFDVLFQAQDHPAREIHDSLWIKSPRRGDLSGYSDLVERVASVHERGWKYRWSPEVASRYILRSQTTAVSARILATRPNPPARFFTVGKVFRSDAVGPTRLPEFHQLDGIEGDEGYTFRDLLGRLDEIASMLGLKLKFKPAYFPFTEPSVEGYVKLPNGRWLELFGAGMFRPEVLEAVGVDYPVGAWGFGIERLAMAFYGVSDIRKLYTRNVDEVREMRVRWL
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMP1_XENLA
Sequence: MAENGTDCEQRRVGMPKEQNNGSFQDPSFMCNRKRRDREERQSIVLWRKPLITLQYFILEVLINLKEWSVRLWHRRMMVVSVLLLLAVLSVAYYIEGEHQQCVQYIEKKCLWCAYWVGLGILSSVGLGTGLHTFLLYLGPHIASVTIAAYECNSVNFPEPPYPDEIICPDEEGTEGAISLWTIISKVRLEACMWGAGTAIGELPPYFMARAARLSGVETDDEEYAEFEEMLEHAQTAQDFATRAKLTVQNLVQKVGFLGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKLFVIITFSKHIVEQMVSLIGVIPSIGPSLQKPFQEYLEAQRKKLHHKGDSGTPQSENWLSWAFEKLVIIMVFYFILSIINSMAQSYAKRVQQKKLSVEKTK
What is the function of this protein?
Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes.  Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine.  Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted by atg2 (atg2a or atg2b) to mediate autophagosome assembly.  In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required.  Modulates ER contacts with lipid droplets, mitochondria and endosomes.
What are the official names of this protein?
Vacuole membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the VMP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS3A_DANRE
Sequence: MAVGKNKRLTKGGKKGAKKKIVDPFSKKDWYDVKAPAMFNIRNLGKTLVTRTQGTRIASDGLKGRVFEVSLADLQNDEVAFRKFKLVTEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRTNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSVGKDIEKACQSIYPLHDVYVRKVKMLKKPKFELGKLMELHGEGGSTSAAAKPAEGDTGAKVERADGYEPPIQESV
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  May play a role during erythropoiesis (By similarity).
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPRA_RAT
Sequence: MDSWFILILFGSGLIHISANNTTTVSPSLGTTRLIKTSTTESAKEENKTSNSTSSVISLSVTPTFSPNLTLEPTYVTTVNSSHSDNGTKRAASTESGGTTISPNGTYGTWLTDNQFTDARTEPWEGNSSSAATTPETFPPADETPIIAVMVALSSLLVILFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNLLPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQGCWPYGNVRVSVEDVTVLVDYTVRKFCIQQVGDVTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHSERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLDTHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGYLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDPYRQKDSYIASQGPLLHTTEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLECVKAEGILDVFQTVKTLRLQRPHMVQILEQYEFCYKVVQEYIDAFSDYANFK
What is the function of this protein?
Tyrosine protein phosphatase which is involved in integrin-mediated focal adhesion formation (By similarity).  Following integrin engagement, specifically recruits BCAR3, BCAR1 and CRK to focal adhesions thereby promoting SRC-mediated phosphorylation of BRAC1 and the subsequent activation of PAK and small GTPase RAC1 and CDC42 (By similarity).
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase alpha, Protein-tyrosine phosphatase alpha, R-PTP-alpha.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Note=Localizes to focal adhesion sites following integrin engagement.