PharMolix/UniProtQA huggingface dataset:
Protein: EIF3B_ASPOR
Sequence: MAPSFDTLSEQDLHEEEEEEIDFSDLKEQFEVKLEEGLDTFIVIDGLPIVPEESRQKLIKFLLRKLNAVGHTSEDAVFMPTNDKNMSEGFAFVEYETPEQAIAAVKQLHGTPLDKKHTLAVNKLMDIDRYGREGRIDEEYKPPTVEPFKEKEHLRSWLSDPNARDQFALYRNDKVGVFWNNKNNPPENVVDRAHWTQLFVQWSPKGTYLASVHPQGVQLWGGPAFSKQKQFPHPFVQLVEFSPGESYLTTWSSRPIQVEEGHPVLSFEEDGKNIIVWDIVSGKPLRSFVSHDLAGGPVEGDAAPKKKVQWPAFKWSADEKYVARMLQGQSISIYELPRMNLLGKTSVKIDGVMDFEWSPATVTRDGVKQYEQLLSFWTPEIGSNPARVALMSVPSKEIVRTRNLFNVSDVKLHWQSQGTYVCVKVDRHSKSKKSMATNLEIFRVREKGVPVEVVDSLKDTVINFAWEPNGGRFVLITTGEAPSGAAVLPKTSVSFFAPEKKGPQAGNFKLVRTIEKKTSNAIYWSPKGRFVVVATVHSQSNFDLDFWDMDFEGEKAEGEKDLAANLQLMKTVEHYGVTDIDWDPTGRYVVSSASVWTHSMENGWNIHTFAGQTLAEHPTDKFKQFVWRPRPPTLLSKEEQKQVRKNLREYSKEFDEEDKYAVDIANTAVVETRKRVLNEWVAWLRREKELMAEEKDAYGIPEDADDAKVAKDAPPVSEDQGEAVVEEIVEEIVEENEEVIG
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3 p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_SHESR
Sequence: MARTVNCVYLNKEADGLDFQLYPGDLGKRIFDNVSKEAWGLWQKKQTMLINEKKLNMMNVDDRKFLEEQMTSFLFEGKDVEIEGFVPEKGQE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: MURD_CAMJJ
Sequence: MKISLFGYGKTTRAIAENLVDKFGPFDIYDDHFIETKKDTLGNLLLNPNDFDDNLSDIEIPSPGFPPKHKLIQKAKNLQSEYDFFYDIMPKSVWISGTNGKTTTTQMATHLLSHIGAVMGGNVGTPLAELDPYAKLWILETSSFTLHYTHKAKPEIYALLPISPDHLSWHGSFDNYVQDKLSVLKRMNECDVAILPKIYANTPTKAHKISYEDEKDLAVKFGIDTEKISFKSPFLLDAIMALAIEKILLDTLSYELLNSFVMEKNKLEELKDSQNRLWVNDTKATNESAVMAALNRYKDKKIHLIIGGDDKGVDLSNLFDFMKNFNIELYAIGISTEKMLDYAKKANLKAYKCEVLSKAVNEISNHLRVNEVALLSPACASLDQFNSYAERGKVFKECVNKI
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP2DK_MESAU
Sequence: MVLLIGDGLWSGVIFTALFLLLVDLMHRRKFWRARYPPGPMPLPGLGNLLQVDFENMPYSLYKFQQRYGDVFSLQMAWKPVVVINGLKAVREVLVNCGEDTADRPPVPIFNHLGYRPKSQGVVFARYGPQWREQRRFSVSTMRDFGVGKKSLEQWVTEEAGHLCDAFTQEAGHPFNPITLLNKSVCNVISSLIYAHRFDYEDPFFNKLLKTLQESFGEDSGFIAEVLNAVPVLLRIPGLPGKAFPKLTAFMDSLYKMLIEHKTTWDPAQPPRGLTDAFLAEVEKAKGRPESSFNDENLHVVVADLFIAGMVTTSTTLSWALLLMILHPDVQSRVQQEIDDVIGQVRRPEMADQARMPYTNAVIHEVQRFGDIAPVNVPHMTSRDVEVQGFLIPKGTTLIPNLSSVLKDETVWEKPLHFHPEHFLDAQGRFVKQEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQPRPSDQGVFALPVTPTPYELCAVVR
What are the official names of this protein?
Cytochrome P450 2D20, CYPIID20.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: LIX1L_RAT
Sequence: METMRAQRLQPGVGVGGRGTLRALRPGVTGAPTSAATPPAGPPPAPPPPAPPPPPLLLAGAPGLPLPPGATGSPAVLREAVEAVVRSFAKHTQGYGRAVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGSFQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNREEADNPNTGIGAFRFMLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRHQMALDWVSREQSVPGALSRELASTERELDEARLAGKELRFHKEKKDILMLAAGQLGNMHSSSC
What are the official names of this protein?
LIX1-like protein.
What is the protein family that this protein belongs to?
Belongs to the LIX1 family.
Protein: PAGP_LARHH
Sequence: MKQMVCWLTAGLLTLGGLPARAGDTVPAVPETPAAPAAPAVQETPASSAAPGFWQRSWDNVETTWRSDRYELYLPAITWHNRAFYDRDKIDEYNEHPWGLGLGRYRYDSDGNWHALYAMFFLDSHDKVEPFAGYAWQKIWRPADDVRLGAGFTVGVTARSDYSYIPFPAILPLVSVEYRRLALQATYIPGGHNNGNVLFGWLRWQL
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CYB_NINTI
Sequence: MTNLRKTHPLMKIINHSFIDLPAPSNISAWWNFGSLLGICLVIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLAEWIWGGFSVDKATLTRFFAFHFILPFIIMALVIVHLLFLHETGSNNPSGINPDSDKIPFHPYYTVKDALGFMFLLLTLLALALFSPDSLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPFLHTANQRSMMFRPISQTLFWILAANLITLTWIGGQPVEHPFIIIGQLASMLYFLLILILMPLAGMFENYMLKPKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL36_SHEWM
Sequence: MKVRASVKKICRNCKIIKRSGVVRVICVEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: END4_ONYPE
Sequence: MLFLGSHVAMKKPHNFQGAIQTAISYGANALMVYSGAPQNTIRTKTEELKIKQALEIVQNNNLSLNNLVGHAPYIINLANPDETKRAFAIDFLSQELERFAAMKINKMVLHPGNYLKTNPQEGISLIAQSLDLIFEKTKHLKTQVALETMAGKGTEIGKNLEELQQIRTQVKNNTRVSFCLDTCHLFDAGYDLKENLEEIIQKIDSILGFQNISVIHINDSKNECNSHKDRHENIGFGKIGFETLLKIIYHRAFACIPKILETPYINDKAPYKREIEMIKAKAFNPELKKLF
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RL33_ALISL
Sequence: MAKGAREKIKLVSTANTGHFYTTDKNKRNMPGKMEIKKFDPVVRQHVLYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: COAX_HAHCH
Sequence: MKELDLDAGNSGLKWRLVESGRVIDRGIIIYGANAQKWSMPTKGACRAFVSSVSSKEVDDAIREVLKDIKDVFWAKTASSYGSLVNAYADYASLGVDRWLALIAAYSKYPEDLCVIDCGTAVTVDYVDKFGVHKGGYIAPGGALMLKSLNVNTAALKGTYGYDSELIPGSSTRECIERGVYYMQKAFVLSVARRCAESRIVCTGGGVKALLGNDEAYTYVEDLVLDGLRIVANAVPVN
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTUB_ECOLX
Sequence: MIKKYWFLMVYSVTAFSVWAQDTPLDTLVVTANRFQEPLSTVLAPVTIVTREDIDRWQVSSVNDVLRRLPGVAISQHGGEGQLSTIFVRGTNSNHTLVLIDGVRLNLAGVSGAADLSQFPVALVQRIEYIRGPRSAIYGSDAIGGVINIITSRENTGTEISAGWGSNSYQHYDISTHQQLGENTRVTLLGDYTYTRGFDAVAYGSTGMQPQSDRDGFLSKTFYGKLEHNLSDTWSGFVRGYGYNNRTKYDAWYSPGSPLIDTRKLYSQSWDAGLRYAGETLQSQLVSSYSHSKDYNYDPHYGRYDTSANLDDMKQYNLQWTNSVTVGHGNVGAGIDWQKQSTTPGTGYLPKGYDQRNTGIYLTGLQKLGDFTLEGAVRNDDNSQFERHTTWQSSAGWEFIEGYRFIASYGTAFKAPNLGQLYGMYGNPNLAPEKSKQWEGAFEGLTGGVNWRISGYRNDISEMINYNPHTLRYYNDGKVHVKGIEATVNFDTGALTHTVSYDYTDARNALTDKPLERRPKLQVKYQLDWQVFDFDWGITYQYMGSRYDSDYSSWPYKSVKMGGVSLWDVAVAYPVTPHLIVRGKIANLFNKDYETGYGYQAAGREYILSGSYTF
What is the function of this protein?
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity).
What are the official names of this protein?
Vitamin B12 transporter BtuB, Cobalamin receptor, Outer membrane cobalamin translocator.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RF4_KLULA
Sequence: MCLELDNNLSDYFKACTYAYYSDYENFIKYYDNEELFDEDDLNFHLCIGIRNSYNFAVKMENSGLKLTSGILSSISARYIMSNKVCDFNFKYLPSGIWYPNVPTKETCIYLLEKDPKYSLVIKTICVLLGWDDVCDKCDKICTEVCFRLSIIFNRRSFCEEDTIYNYKIHENKNILEKVEKDKYLLPETILRNKDTTLEIFFKYNYTSKQSNIEQIIDDMLYTYIDYSQNTEFGPMDCVSVDKSVYYNMVSYKPYLDININTVEFNFLNSAYVLKHHKEYPDDLCKKAVLNLLVNDIYDSNFVSLYRPFYFYTYKTLNKYMVQKLLIDFPRQRYAILVNYAIMNITEDLENYSPDIDLIRIAYASGSIEFYNIMMNKAKKEGGMCQHLDFENEKYIFKYHKYEDVDFDNLHKNNGHPLLLRATHLNFP
What is the function of this protein?
Not known.
What are the official names of this protein?
RF4 protein.
Protein: TREM3_MOUSE
Sequence: MSPLLLWLGLMLCVSGLQAGDEEEHKCFLEGENLTLTCPYNIMLYSLSLKAWQRVRSHGSPETLVLTNTRKADFNVARAGKYLLEDYPTESVVKVTVTGLQRQDVGLYQCVVYLSPDNVIILRQRIRLAWCQGKPVMVIVLTCGFILNKGLVFSVLFVFLCKAGPKVLQPSKTSKVQGVSEKQ
What is the function of this protein?
Forms a receptor signaling complex with TYROBP/DAP12 which mediates activation of macrophages as part of the innate immune response.
What are the official names of this protein?
Triggering receptor expressed on myeloid cells 3, TREM-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: BIOD_HELPY
Sequence: MLFISATNTNAGKTTCARLLAQYCNACGVKTILLKPIETGVNDAINHSSDAHLFLQDNRLLDRSLTLKDISFYRYHKVSAPLIAQQEEDPNAPIDTDNLTQRLHNFTKTYDLVIVEGAGGLCVPITLEENMLDFALKLKAKMLLISHDNLGLINDCLLNDFLLKSHQLDYKIAINLKGNNTAFHSISLPYIELFNTRSNNPIVIFQQSLKVLMSFALK
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_PSEU2
Sequence: MRHYEIIFLVHPDQSEQVGGMVERYTKLIEEDGGKIHRLEDWGRRQLAYAINNVHKAHYVMLNVECTGKALAELEDNFRYNDAVIRNLVIRRDEAVTGQSEMLKAEENRSERRERRDRPEHSDSADGDDGDNSDVSDNADE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: LEUC_SHESR
Sequence: MTTPSTSTTPKTLYQKVWDAHVVATPEGEAPIIYVDRHLVHEVTSPQAFSGLKVAGRKLRAPEKTFATMDHNTSTRSASLDALSPMARTQVETLAQNCKDFGVRLYDIHHPNQGIVHVMGPELGITLPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLRQLKAKTMKIEVRGQVTDGVTAKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAIEMGAKAGMVAPDQTTFDYLEGREFAPKGEDWAEAVAAWKALKTDVGAEFDATVVLDAADIAPQLTWGTNPGQVVAIDAPVPNPADEANPTIRASMEKALDYIGLTAGTPMTDVAINKVFIGSCTNSRIEDLRSAAKQAKGRKVASGVTAIVVPGSGQVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNDDRLEAGDRCASTSNRNFEGRQGRGSRTHLVSPAMAAAAAIAGHFVDIRKPY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: LRC43_MOUSE
Sequence: METSESSTSDYRQTEGEGEGVPGTLSTAVCEHLRKLCLREFPCGIGSWNKSRFLPQKCRVWRELVPKEEETLVPEEETVEALLGLVRSNHSPWAMLKDASAEDRFLRELAIQNPLMIKDTFFYSYFRSLRVVNKGVSLVDKDLLKFLKLEELVLSANKIEEIDANNLPPTLKVLELYGNLIASMECLCSAPPPRLQHLGLGHNKLLGPLESLYVTSHNWPQLVSLDLGFNNLTDLQNMILGLSTLRHLRLLVLQGNPLSLVPYYRGFTIDSLAHLCVLDDITVSPNEKHQFRGLNIHGDLLAREAQFVVTIGNVRGVLDSSILDPEPGPDGPFISYSYYVTYDFVEDEDMERNVSGLVEATHHDSVLDEIDKHFSGTDEEDQQEDPLDGRHRHRGRQRFHPGSTEEMSKELSEFIAKEMSQMAEGSVESGITEVDWSETSISIHSAPLPQSIDSSEELAKLRPKIDIQLCPSPGTVLFNTVHKPWSDVIPCTYEMKHTLKELIRVKAFLLAGTTVSIVEEKILSWPVVPTPVESPLPAKKGKDNNKKKEPAKDKVHKKKKEPPRELRQDPPVLTVLGSGLVYLEPLLAGEAVVSTVCNFGVVRTLETDRLTHARDSKKVKKSLKKDRSKTVPPTMESGYQPEPLSVEVQIQLHQYRSVEEAFLSLID
What are the official names of this protein?
Leucine-rich repeat-containing protein 43.
Protein: SYC_HAES1
Sequence: MLKIFNTLTREKEVFKPISENKVGMYVCGVTVYDLCHIGHGRTFVCFDVIARYLRYLGYELTYVRNITDVDDKIIRRSLENRETCEQLVDRMVVEMYKDFDALNVLRPDFEPRATHHIAEIIALVEKLIARGHAYVADNGDVMFDVESFKEYGKLSRQDLTQLQAGARVEISEIKKNPMDFVLWKMSKENEPSWNSPWGAGRPGWHIECSAMNCKHLGEHFDIHGGGSDLMFPHHENEIAQSCCAHGNRYVNYWIHSGMIMVDKEKMSKSLGNFFTIRDVLNHYDAESVRYFLLTAHYRSQLNYSEENLDLAHGALERLYTALRGTDKSAVAFGGENFIAQFTEAMNDDFNTPNAISVLFEMAREINRLKNEDKLLADGLAARLRELAGILGLLEQDPEDFLQAGSDDAEIAKIEALIKQRNDARQAKDWARADAARNELTTMGVILEDGSNGTMWRKM
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPSD_ASPOR
Sequence: MLVLVSLVLCLTGFCLLQWALKERKIVKGLPPGPRPKPIIGNLLDLPPPGALDWLHWLKHKELYGPISSVTIFGQTIIIINGHRVANELMEKRSGVHSSRPHVPIAELAGWQYTLGFIPYDSRLRAYRRALHQEMGNATSISKYHNILDMETHRLLFRILKTPDCLMQHLRKEAGSIILRITYGYITEPEAYDPLIDLVDKAMEDFAQVILPGGWLVNFIPMLKYLPSWFPGCDWQRRAKAFKQRAKAMTDIPYAFVKQQHEQQKHIPSYVSRLLEQNNIKLGSEEELVVKWSAQSIYGGGAETSVSVFACFFQVMALHLNVQKKAQEEIDRVVGASRLPDLSDCKNLPYINAVVKEVLRWHPVAPMGVAHASSKEDIYHRYVIPKGAILVPNIWAMAHDPDFYHNAMDFEPERFLKSGRNEQNPEYDPHQFIFGFGRRTCPGQHLVSANLSLGVARVLAVFNITNAVRDGKKVPISPEFSPGVISRPAPFELSIQVRNAECKRLIEAVGMKFPWEESHAEALAQLRI
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of 2,4'-dihydroxy-3'-methoxypropiophenone (PubMed:32885554).  The first step of the pathway is the conversion of acetate into acetyl-CoA by the acyl-CoA ligase ppsA (PubMed:32885554).  Acetyl-CoA is then used as a starter unit by the polyketide synthase ppsB and condensed with 4 malonyl-CoA unit to produce the pentaketide backbone (PubMed:32885554).  During polyketide extension, the polykedite chain is probably reduced and dehydrated by the KR and PT domains, respectively (Probable).  O-methylation seems to be catalyzed by an unknown methyltransferase rather than by the CMeT domain of ppsB (Probable).  Two hydroxylations and one further decarboxylation step catalyzed by yet unknown enzymes are then required to yield 4'-hydroxy-3'-methoxypropiophenone (Probable).  PpsC functions as a carrier protein to transport 4'-hydroxy-3'-methoxypropiophenone to a specific cell compartment in which 4'-hydroxy-3'-methoxypropiophenone is hydroxylated to 2,4'-dihydroxy-3'-methoxypropiophenone by a still to be identified enzyme (PubMed:32885554).
What are the official names of this protein?
Cytochrome P450 monooxygenase ppsD, 2,4'-dihydroxy-3'-methoxypropiophenone biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FNO_METOG
Sequence: MKVGIMGGTGNIGEGLARRIXIGGKYDVMIKGRDKA
What is the function of this protein?
Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i. e.  the reduction of F420 with NADPH.  In M. organophilum, an alcohol-fermenting methanogen containing an NADP-dependent alcohol dehydrogenase, is probably involved in the regeneration of F420H(2) required for CO(2) reduction to methane.  Thus, during growth on alcohol and CO(2), the F420-dependent NADP reductase probably has the function of coupling the NADP-dependent oxidation of the alcohol to the aldehyde with the F420-dependent reduction of CO(2) to methane.
What are the official names of this protein?
F420-dependent NADP reductase, F420H2:NADP oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the F420-dependent NADP reductase family.
Protein: ACA8_ORYSJ
Sequence: MEKLDRYLQEHFDVPAKNPSEEAQRRWRQAVGTIVKNRRRRFRWVPDLDRRSLDKAKVRSTQEKIRVALYVQQAALIFSDDELALITSKHDSKALKMHGGVDGISKKVRSSFDHGICASDLDTRQNIYGVNRYAEKPSRSFWMFVWDAFQDMTLIILMVCALLSVAVGLATEGWPKGMYDGLGIILSIFLVVMVTAVSDYKQSLQFKELDNEKKKIFIHVTRDGRRQKISIYDLVVGDIVHLSIGDQVPADGLYIHGYSLLIDESSLSGESDPVYVSQDKPFILAGTKVQDGSAKMIVTAVGMRTEWGKLMSTLSEGGEDETPLQVKLNGVATVIGKIGLVFAILTFLVLLVRFLIDKGMTVGLLKWYSTDALTIVNYFATAVTIIVVAVPEGLPLAVTLSLAFAMKKLMNDKALVRHLSACETMGSAGTICTDKTGTLTTNYMVVDKIWISEVSKSVTSNTISGELNSVVSSRTLSLLLQGIFENTSAEVVKEKDGKQTVLGTPTERAILEFGLGLEGVHDAEYSACTKVKVEPFNSVKKKMAVLISLPSGTSRWFCKGASEIILQMCDMMVDGDGNAIPLSEAQRKNILDTINSFASDALRTLCLAYKEVDDDIDDNADSPTSGFTLIAIFGIKDPVRPGVKDAVKTCMSAGITVRMVTGDNINTAKAIAKECGILTEDGVAIEGPEFHSKSPEEMRDLIPNIQVMARSLPLDKHTLVTNLRGMFDEVVSVTGDGTNDAPALHEADIGLAMGIAGTEVAKESADVIVLDDNFTTIINVARWGRAVYINIQKFVQFQLTVNIVALVINFVSACITGSAPLTAVQLLWVNMIMDTLGALALATEPPNDEMMKRPPVRKGESFITKVMWRNIMGQSLYQLFVLGALMFGGESLLNIKGADSKSIINTLIFNSFVFCQVFNEINSREMQKINVFRGIISNWIFIAVIAATVAFQVVIIEFLGTFASTVPLNWQHWLLSVGLGSISLIVGVILKCIPVGSGETSATPNGYRPLANGPDDI
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell, into the endoplasmic reticulum, or into organelles.
What are the official names of this protein?
Probable calcium-transporting ATPase 8, plasma membrane-type, OsACA8, Ca(2+)-ATPase isoform 8.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RF3_ENTFA
Sequence: MTINQKEAVDSRRTFAIISHPDAGKTTITEQLLLFGGAIRQAGTVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQDKRINILDTPGHEDFSEDTYRTLMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEELLDIESYPMNWPIGMGKGLEGLYDIYNERVELYRPENNGGERFIPLKDGDIPSDLPLHNNSVYQQVLEDVELLVEAGDEFSEEKIARGDQTPVFFGSALTNFGVQTFLETFLQFAPAPHAHKTEEGGEVSPYEKEFSGFVFKIQANMNPAHRDRIAFVRICSGVFERGMDVTLGRTGKKVKLSNVTQFMADARENVTEAVAGDIIGVYDTGNYQIGDTLYEGKMNVQYEELPSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEVFQYRMSNEYNAEVVMTPMGSKIARWINPEDLDERMSSSRNILARDRFDQPLFLFENQFAERWFADKYPDVELKSLM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_ALBFT
Sequence: MQLIPLPAFTDNYIWMVHDERHALVVDPGDAQPVLEALQQLGLQLETILVTHHHPDHTGGVAALRAATGAQVFGPAREPMPEPLIRLTGDQQLQALGLNFQVIDVPGHTACHIAYFCADVDGAPLLFCGDTLFSAGCGRLFEGSPAQMLASLDTLAALPDATRVCCAHEYTLSNLKFACAVEPVNQALTDYTVKAEALRSQQQPTLPSSILLERQINPFLRTRQATVTQAVQAFDASARDEVSIFAALRQWKNQF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: DESR_BACSU
Sequence: MISIFIAEDQQMLLGALGSLLNLEDDMEVVGKGTTGQDAVDFVKKRQPDVCIMDIEMPGKTGLEAAEELKDTGCKIIILTTFARPGYFQRAIKAGVKGYLLKDSPSEELANAIRSVMNGKRIYAPELMEDLYSEANPLTDREKEVLELVADGKNTKEIAQELSIKSGTVRNYISMILEKLEVKNRIEAITRSKEKGWFK
What is the function of this protein?
Member of the two-component regulatory system DesR/DesK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase.
What are the official names of this protein?
Transcriptional regulatory protein DesR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STP9_ARATH
Sequence: MAGGAFVSEGGGGGNSYEGGVTVFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLSKFFPEVDKQMHEARRETAYCKFDNQLLQLFTSSLYLAALASSFVASAVTRKYGRKISMFVGGVAFLIGSLFNAFATNVAMLIVGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILIANLINYGTSQMAKNGWRVSLGLAAVPAVIMVIGSFVLPDTPNSMLERGKYEQAREMLQKIRGADNVDEEFQDLCDACEAAKKVDNPWKNIFQQAKYRPALVFCSAIPFFQQITGINVIMFYAPVLFKTLGFADDASLISAVITGAVNVVSTLVSIYAVDRYGRRILFLEGGIQMIVSQIVVGTLIGMKFGTTGSGTLTPATADWILAFICLYVAGFAWSWGPLGWLVPSEICPLEIRPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFGGMVAVMTVFIYFLLPETKGVPIEEMGRVWKQHPFWKRYMPDDAVIGGGEENYVKEV
What is the function of this protein?
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.  Mostly transports glucose, and barely galactose, xylose and mannose.
What are the official names of this protein?
Sugar transport protein 9, Hexose transporter 9.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ILVC_METC4
Sequence: MRVYYDRDADLNLIKGKNVVIVGYGSQGHAHALNLRDSGVKDIVIALREGSATAKKAEHEGFKVMNVADAAKWGDVVMMLTPDELQGDIYKESLEPNMKQGAALLFAHGLNVHFNLIEPRKDLDVLMVAPKGPGHTVRGEYLKGGGVPTLIAIAQDASGNAHDLGLSYASANGGGRAGIIETTFKEECETDLFGEQAVLCGGLVELIKAGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIVTPETKAEMKRVLNDIQSGIFTRNWMLENKVGQTSFKATRAKLAAHPIEEVGAKLRGMMPWISEKALVDKTKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PNG7_ASFB7
Sequence: MMCMIIRRNRFTGVHDQNLIFNVKSTDVNCLV
What are the official names of this protein?
Uncharacterized protein pNG7.