PharMolix/UniProtQA huggingface dataset:
Protein: HSLV_PSESM
Sequence: MTTIVSVRRHGKVVMAGDGQVSLGNTVMKGNAKKVRRLYHGEVIAGFAGATADAFTLFERFEAQLEKHQGHLVRAAVELAKDWRTDRSLSRLEAMLAVANKDASLIITGNGDVVEPEDGLIAMGSGGAFAQAAARALLLKTDLSAREIAETSLHIAGDICVFTNHNITIEEQDLAD
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_SHEDO
Sequence: MNLAAMDPSNYDAQLAEKKRKLSEGFAEFAPPELEVFASEPAHYRMRAEFRVWHEGDDLYYYMFDKVLDAKVRCEQYLPASTLINAIMTSLVEELRPNHSLRHRLFQVDFLSTLSGEILVSLLYHRQLDEQWQVEAAALKQRLSSQFNVNIIGRARKQKIDLDKDFVVETIKVNGQDLHYKQIENSFTQPNAKVSIKMLEWAIDATKQSQGDLLELYCGNGNFTIALAQNFNRVLATELAKPSVGAAQYNIAINNVDNVQIIRMSAEDFSDAMAKKRSFRRLEGIDLDSYNCNTIFVDPPRAGIDDETLKLIQGYERILYISCNPETLKDNLQTLSSSHKITRFALFDQFPYTHHMESGVLLERK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: SPCS2_HUMAN
Sequence: MAAAAVQGGRSGGSGGCSGAGGASNCGTGSGRSGLLDKWKIDDKPVKIDKWDGSAVKNSLDDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLAIERKIK
What is the function of this protein?
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (PubMed:34388369).  Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).
What are the official names of this protein?
Signal peptidase complex subunit 2, Microsomal signal peptidase 25 kDa subunit, SPase 25 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the SPCS2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PYRG_GEOSL
Sequence: MKTKFIFVTGGVVSSIGKGLASASLGALLESRGLRVTMQKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERYTSARLSKRSNFTTGQVYFSVIEKERRGDYLGGTVQVIPHITDEIKHKILENAKGADVAIVEVGGTVGDIESLPFLEAIRQFKADRGAGNVLYIHVTLVPHIKTAGELKTKPTQHSVKELREIGIQPDILICRCEMELPRDMKAKIALFCNVEEKAVITSTDAEHIYAVPLALHKEGLDEQVVEKLNIWTKAPDLSPWHSVVEKLRSPLRGEVRIAIVGKYVNLTESYKSLSEALTHGGIANDCRVVLTYLDSERIESEGIGSSFDDIDAILVPGGFGERGTEGKIKAIEYARTQKIPFFGICLGMQMAVVEYARNVCGLEDACSSEFRPDCANPVISLMEEQRDIDRLGGTMRLGAYPCSLTKGTFAQKAYGSLEISERHRHRYEYNNAFRETLVANGLVVSGLYKEGDLVEIVEVADHPWFLGCQFHPEFKSKPLNPHPLFRAFIAAALDRKDKRR
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: AZOR_BRASB
Sequence: MKLLHIDSSIAGVGSVTRELSAEIVALLKGADKSWNVIYRDLVAEPLSHLTGGYLAALQGAPADQAVQADVGAGLAVMEDFLAADVIVIGAPMYNFGVPSQLKAWIDRLAVPGKTFSYGEHGPVGLCKGKKVIVASARGGIFSAGSPLAALDHQENYLLSFFGFLGIAEISFVRAEGVALGPVVRAKAIAAAKEHAAKLAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: Y8260_DICDI
Sequence: MQQQSPPTAPQQQQQQQRERETYQLDHIGVHCNVTDCRVLDFLPFNCDLCNLSFCMEHKGYENHKCKNIEQRENKIVHPCPVCNCLIKVDSLANLDQTVRFIISVHMDTDCKFNQSKAPKSFKCSLKTCKTSEFVEVKCDKCKSNYCLKHRFPTNHSCTGKPIINSLSKPINTTINNNINNNTNNINNNINNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNKLIYPGNIKKNIVEDKQYYLEQKNQKSELQKLREEQNQRYKSSEEIGEIGIIQTNGARIQYDFMATDTLRSVQKFINSNRTDGTCSYALCTQPTGNPFTLNQLNLSIRQLGLLPVSTLYMLPLDNSNNFNNSGNNNNNSSDQSLLSYLNPFKYFK
What are the official names of this protein?
AN1-type zinc finger and UBX domain-containing protein DDB_G0268260.
Protein: PHS_SHEDO
Sequence: MNALTSMKCEACQADAPKVSDQELAELIRLIPDWGVEVRDGIMQLERVYKFKNFKLAMAFTNKLADAAEEEGHHPGILTEWGKVTVTWWSHSIKGLHKNDFIMAAKTDQLLD
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: AMY1C_HUMAN
Sequence: MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLSGLLDLALGKDYVRSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAILDKLHNLNSNWFPEGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRYFENGKDVNDWVGPPNDNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL
What is the function of this protein?
Calcium-binding enzyme that initiates starch digestion in the oral cavity (PubMed:12527308).  Catalyzes the hydrolysis of internal (1->4)-alpha-D-glucosidic bonds, yielding a mixture of maltose, isomaltose, small amounts of glucose as well as small linear and branched oligosaccharides called dextrins (PubMed:12527308).
What are the official names of this protein?
Alpha-amylase 1C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYFA_YEAST
Sequence: MSDFQLEILKKLDELDEIKSTLATFPQHGSQDVLSALNSLKAHNKLEFSKVDTVTYDLTKEGAQILNEGSYEIKLVKLIQELGQLQIKDVMSKLGPQVGKVGQARAFKNGWIAKNASNELELSAKLQNTDLNELTDETQSILAQIKNNSHLDSIDAKILNDLKKRKLIAQGKITDFNVTKGPEFSTDLTKLETDLTSDMVSTNAYKDLKFKPYNFNSQGVQISSGALHPLNKVREEFRQIFFSMGFTEMPSNQYVETGFWNFDALYVPQQHPARDLQDTFYIKDPLTADLPDDKTYMDNIKAVHEQGRFGSIGYRYNWKPEECQKLVLRTHSTAISARMLHDLAKDPKPTRLFSIDRVFRNEAVDATHLAEFHQVEGVLADYNITLGDLIKFMEEFFERMGVTGLRFKPTYNPYTEPSMEIFSWHEGLQKWVEIGNSGMFRPEMLESMGLPKDLRVLGWGLSLERPTMIKYKVQNIRELLGHKVSLDFIETNPAARLDEDLYE
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIE_SALAR
Sequence: MAAIQGIEGVISQLQATAVGARGQETQSQPTMSFAGQLHAALDRISDRQTEARVQAEKFTLGEPGIALNDVMADMQKASVSMQMGIQVRNKLVAAYQEVMSMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: SYE1_SYNWW
Sequence: MSNIRVRFAPSPTGALHMGGARTALFNWLFARQNGGKFILRIEDTDFRRSREDSAQGIVEGLSWLGLDWDEGPDIGGPLGPYRQSERGDIYSRYLQELLDSGQAYYCFCSPEDLQKEREEAAQEKRDYKYGGRCKALKPEEASEMLQAGKPAVIRLKVPLDGNTVVPDLIRGDVSFSNALFDDFIIAKSDGWPTYNFAVVVDDFSMQISHVLRAEEHLSNTPRQLLIYRALGLKEPAFAHLSMILAPDRSKLSKRHGAISVQEFENQGYLPEALVNYLALLGWSTGKDIDIWSREEMMREFSLEHISKSPAIYDLEKLAWMNGQYMMRLDIESLMALVEPQAQQQGWLNEDNFDYFQQAVELVRNRAKTRDELLDALGYFFEEVKQYDEKGVKKHFGQQKASTMLSEVLEIVSNMGSFSAAELEEAFRQRAQELKIKAADLIHPTRLALSGRTATPGLFELMEVLGQEKCISRLEKALDFIAKLTTHGPEGHNHR
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_SYNWW
Sequence: MPKVALYDMSGAQVGEIELNDSVFGIKPNQAVMFDFVKMQLANKRAGTASSKTRAEVRGGGKKPWRQKGTGRARVGSSRNPVWTKGGVAFGPRPRDFSYRLPRKVRRLAMKSALSSKVLDNNIVVLDSLTFDEPKTRLMVQTLKSLPVGKKTLVVTAYGDPNVIKSARNIPGVKPLRADFINVYDLLNYDTLLITREAVARIEEVFA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CAP17_ARATH
Sequence: MPGLKTHIIGKFKDKASIGKARLVHSFGSTAVKYIHLALLKSTTRTPNKPPNSDYVSAVISYSNSRYAPAAFSAALWRLRVTKNAIVATKSLIVIHKLIKSSRDKFEGLGHGRNNLKLNEFSDKSSNLTLELSQWIRWYGQYLDRLSWVPKVLGSFPNLLVNPKDKVEEKDRVSSYQTGYIIRQTDSLVSFFEHICTRPEIPPMFQNKIVDEIRELVIEDYFKIVRLVMVRLQVLFERLIKPGVKPIGDLGLNDFSLLLVRLVECKESLSGLFWRCRRLADDFWCLVEMLKAETEKKNNKQMIELAGLVQTTVKDDEEMIELVGSVQPEWVTFDDSDF
What are the official names of this protein?
Putative clathrin assembly protein At5g10410.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin in the Golgi area.
Protein: BPT_BURVG
Sequence: MTHPTELPLSPLSALQFYATAPYPCSYLDGRIARSQVATPSHLINSDIYTELVKAGFRRSGVFTYRPYCDGCRACVPVRVPVRAFTPSRTQRRMWKRHRALVATVSPLHYDEEHYALYMRYQSARHAGGGMDRDSRDQYEQFLLQSRINSRLVEFRDLDASGGEPGKLRMVSMIDILGDGLSSVYTFFEPDDAHTSYGTYNILWQIEQARSLGLPYVYLGYWIRESPKMAYKANFHPLEGLLDGRWKTLDPARVDLPPVDAALARAPLPGGHSGAG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTD1_YEAST
Sequence: MSKPGRTILASKVAETFNTEIINNVEEYKKTHNGQGPLLVGFLANNDPAAKMYATWTQKTSESMGFRYDLRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYHNVRYLDKENRLKSILPCTPLAIVKILEFLKIYNNLLPEGNRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNNIQKFTRGESLKLNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYKFPTEYIKEGAVCINFACTKNFSDDVKEKASLYVPMTGKVTIAMLLRNMLRLVRNVELSKEK
What is the function of this protein?
Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.
What are the official names of this protein?
Methylenetetrahydrofolate dehydrogenase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COBQ_NOSS1
Sequence: MAMKSIMVVGTTSHAGKSLISTAICRILSRRGWRVAPFKGQNMALNAYVTANGGEIGYAQAVQAWAAGVVPWVEMNPILLKPQGDMTSQVIIRGRPVGRVNAADYYEQYFEPGWRAIEESLQHLATEFDLVVCEGAGSPAEINLKHRDLTNMRVAKYLNAPTLLVVDIDRGGAFAHVVGTLELLDPEERQLIKGVVINKFRGQRSLLDPGIKWLEERTGIPVVGVIPYLQEVFPAEDSLDLLERKTHKAHADLQITVVRLPRIANFTDFDPLESEPTVAVKYISPKQDLGHPDAVILPGTKTTIADLILLQKTGMAEAIQNYAASGGTVLGICGGYQILGQMIADPEGIEGQAGRYQGLNLLPIRTVITGQKIARQRQVSSNFPQQGLPVNGFEIHQGRSRVEPQGDSQAFQPLFDDVNLGLVDSCQSVWGSYLHGLFDNGPWRRAWLNRLRQQRGLKSLPTGVANYREQREQMLDNIATEVENHLDLTPFLP
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: FCTA_RHOPS
Sequence: MTKALDGVRILDFTHVQSGPTCTQLLAWFGADVIKVERPGTGDITRGQLQDIPKVDSLYFTMLNHNKRSITLDTKNPKGKEVLTALIRSCDVLVENFGPGVLDRMGFTWDKIQEINPRMIVASIKGFGPGPYEDCKVYENVAQCTGGAASTTGFRDGPPLVTGAQIGDSGTGLHLALGIVTALYQRQHTGRGQRVTAAMQDGVLNLSRVKLRDQQRLAHGPLKEYSQFGEGIPFGDAVPRAGNDSGGGQPGRILKCKGWETDPNAYIYFITQAPVWEKICDVIGETGWKTHPDYATPPARLKHLNDIFARIEQWTMTKTKFEAMDILNSDDIPCGPILSMKELAEDPSLRATGTVVEVDHPTRGKYLSVGNPIKLSDSPTEVKRSPLLGEHTDEVLREVLGFNDHQIAEIHDSGALAPPRKQAAE
What is the function of this protein?
Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR).  Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (By similarity).
What are the official names of this protein?
Formyl-CoA:oxalate CoA-transferase, FCOCT, Formyl-coenzyme A transferase, Formyl-CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. Frc subfamily.
Protein: ACCD_AGRVS
Sequence: MNWITNYVRPRINSMLGRRDVPDNLWIKCPETGEMVFHKDLEENKWVVPASGYHMKMPAKARLADLFDGGKYEAFAQPKVAQDPLKFRDSKKYSDRLKDSRTKTEQEDTIVAGLGTVEGLKLVAVVHEFNFMGGSLGIAAGEAIVKAFERAIAEKCPLVMFPASGGARMQEGILSLMQLPRTTVAVDLLKEAGLPYIVVLTNPTTGGVTASYAMLGDLHIAEPGAEICFAGKRVIEQTIREKLPEGFQTSEYLLEHGMVDMVVKRHDIPATLARTLKILTKQPATVVGANDDKTLSVIEASRAVSA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLAF_MACMU
Sequence: MAPRTLLLVLSGALALTETWAGSHSLRYFSTAVSRPGRREPQYRYIAVEYVDDTQFLRFDSDAAIPRMEPRAPWVEQEGPQYWERTTGYAKANARTDRVALRKLLLRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVARITQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDREATLRCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPQPLTLRWESSSQPTIPIVGIVAGLAVLAVVVTGAVVAAVMWRRKSSDRNRGSYSQPTM
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
Mamu class I histocompatibility antigen, alpha chain F, Leukocyte antigen F, MHC class I antigen F.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SECA_PSESM
Sequence: MFAPLLKKLFGSKNEREVKRMLKTVQIVNAFEEQMVALSDEQLRAKTEEFKARIAKGETLDQLLPEAFAVAREAGKRVMGMRHFDVQLIGGMTLHEGQIAEMRTGEGKTLVGTLAVYLNALSGKGVHVVTVNDYLARRDANWMRPLYEFLGLTVGIVTPFQPPEEKRAAYAADITYGTNNEYGFDYLRDNMAFSMDDKFQRELNFAVIDEVDSILIDEARTPLIISGQAEDSSKLYTEINRLIPKLEQHIEEVEGEVTKPGHFTVDEKTRQVELNEAGHQFIEEMLTEVGLLAEGESLYSAHNLGLLTHVYAGLRAHKLFNRNVEYIVQDGQVLLVDEHTGRTMPGRRLSEGLHQAIEAKENLNIQAESQTLASTTFQNYFRLYNKLSGMTGTADTEAFEFHQIYTLAVMVIPPNKPLARKDFNDLVYLTAEEKYAAIVTDIKACLAENRPVLVGTATIETSEHMSRLLNNEGIEHKVLNAKFHEKEAEIIAQAGRPGALTIATNMAGRGTDILLGGNWEVEVANLEDPTPEQIAQIKADWQKRHQQVIEAGGLHVIASERHESRRIDNQLRGRAGRQGDTGSSRFYLSLEDSLMRIFASDRVKNFMKALGMQSGEAIEHRMVTNAIEKAQRKVEGRNFDIRKQLLEFDDVANEQRKVIYHMRNSLLAAENIGDTIADFREEVLNSLVSQHIPPQSLPEQWNVAGLEAALNTDFAVKMPIQQWLDEDDNLHEDSLREKIMAQLLVAYNEKEDQASAEALRSFEKQILLRVVDDLWKDHLSTMDHLRHGIHLRGYAQKNPKQEYKRESFTLFQELLDSIKRDTIRVLSHVQVRREDPEEEEARLRREAEELASRMQFEHAPAPGLDQPLADEEGGEVPVAVVSEPIRNDQKLGRNELCWCGSGKKFKHCHGQIN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: DXR_RALSO
Sequence: MMRITVLGATGSIGDSTLDVVRRHPDRYRVFALTANTQVDKLAALCRVFRPAMAVVGSATAAEVLRDQLGAEATGIDIRFGPEALEEAAAHPDCDAVMAAIVGAAGLRPTLAAVRAGKRVLLANKEALVMSGALFMDAVRQHGATVLPIDSEHNAIFQCLPQQRPSFGHGVARIVLTASGGPFRTRAVETLAEVTPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAHWLFNVPVERLEVLIHPQSVIHSMVAYDDGSVLAQLGNPDMRTPIAYGLAYPERIEAGVPLLDLAATGTLAFEAPDLHRFPCLALAFDALRAGGTAPAVLNAANEVAVEAFLQRRIRFTEIAAVVGDTLARTAIGPADSLDTVFAADAQARRRAEHYIAASCLQS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: LPXA_NEIMB
Sequence: MTLIHPTAVIDPKAELDSGVKVGAYTVIGPNVQIGANTEIGPHAVINGHTSIGENNRIFQFASLGEIPQDKKYRDEPTKLIIGNGNTIREFTTFNLGTVTGIGETRIGDDNWIMAYCHLAHDCVIGNHTIFANNASLAGHVTIGDYVVLGGYTLVFQFCRIGDYAMTAFAAGVHKDVPPYFMASGYRAEPAGLNSEGMRRNGFTAEQISAVKDVYKTLYHRGIPFEEAKADILRRAETQAELAVFRDFFAQSARGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_PHEZH
Sequence: MIPVSGFEGRTVAVFGLARTGLAAARALVAGGAKVALWDDKPAAREAAQAEGFELTDLTRADWREFAAVMLSPGVPLTHPAPHWTVERAREAGAEIVGDIELFARTVNAAPEHKRPKIVAITGTNGKSTTTALIGHICAEAGRDVRIGGNIGYGVLGLEDMHGGAVYVLELSSYQLDLTSSLHADVTVILNISPDHLERHGTMDEYVAAKRRILLNQGKGDTAVIGVDDPWGQRICTEITAANRRTIVPVSASKAMSRGVYALDGLLYDATGERAQEVADLKRARSLPGRHNWQNAAAAYAAARGLGISGEEAAQHLMTFPGLAHRMETVAVLGKVRFVNDSKATNADAARQAMSSYPKFYWIAGGLPKTGGIDGLIDLFPRIEKAYLVGEAAPAFADVLRGKAPAVESGTIEAAVRQAYADARAAGQEAIVLLSPACASFDQFADFEERGEAFRAAVQKLADGQADAA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSM5_RAT
Sequence: MRLWLRGLVYQARRSSWGVFRIHTQPPPPPIPEVVATWEAISLGKRPVPEYFNFAHDVLDVWSQLEKTGHRPPNPAFWWVNGSGTEVKWTFEELGKQSRKAANILEGACGLKPGDRLMLVLPRLPEWWLTIVACMRTGVVMIPGISQLTQKDLKYRLQAARVKSIITSDALAPHVDAISADCPSLQSRLLVSDTSRPGWINFRELLRVASPEHNCLRTRSGDSMAIYFTSGTTGTPKMVEHSQCSYGLGFVASGRRLMALTESDIFWNTTDTGWVKAAWTLFSAWANGACVFVHELPQVDAQTILNTLCRFPITTICCVPTLFRLLVQEDLTRYKFQCLRHCLAGGEALNSDVRDKWKNQTGLEIHEGYGQSETVLICGNFRGSTIKSGSMGKASPPYDVQIVDEEGNVLPPGKEGNIAIRIKPTRPFCLFNCYLDNPEKTAASEQGDFYITGDRAHMDEDGYFWFVGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLSPAYVSHDPEALTRELQEHVKTVTAPYKYPRKVAFISELPKTVSGKILRSKLRNQEWGR
What is the function of this protein?
Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism.
What are the official names of this protein?
Acyl-coenzyme A synthetase ACSM5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: BIOD_BACSU
Sequence: MRGFFVTGTDTEVGKTVISSGLAALLKDNNRHVGVYKPFLSGISRHHPDSDTSLLKDMSQTSLSHEDITPFAFKAPLAPYVAGKLEGKTVTMEEVLSHWGRIREKHECFIVEGAGGISVPLGEDYLVSHVIKALQLPMIIVARPRLGTINHTFLTVKYAESMGLPIAGIIINGISDSPDEDEKTNPEMIERLCGVPILGVTPKLANVTKETVLHMVKDHINLSLLMNQVGV
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_THESQ
Sequence: MPKILKFNEEARRALERGVDKVANAVKVTLGPKGRNVVIEKSWGSPTITNDGVSIAKEIELEDKFENLGAQLVKEVASKTNDVAGDGTTTATVLAQAMIKEGLKNVAAGANPILLKRGIDKAVEKAVEEIKKVSKKLSGREDIAHVAAISANSAEIGELIAEAMDKVGEDGVITVEDSKTLETYVEFTEGMQFDRGYISPYFVTDAEKMEVVLKEPFILITDRKLSAVKPLIPILEKVAQTGRPLLVIAEDVEGEVLTTLVLNKLKGTLQSCAVKAPGFGERRKAMLQDIAILTGGQVASEELGINLEDLTLEDLGRADLVRVKKDETIIIGGKGDPEAIKKRIAQIKAQIEETTSEYEKETLQERMAKLAGGVAVIKVGAATETELKEKKHRIEDALSATRAAVEEGIVPGGGVTLLRARKAVEKVIEELEGDEKIGAQIVYKALSAPIKQIAENAGYDGAVIIEKILSNDDPAYGFDALRGEYCNMFERGIIDPAKVTRSALQNAASIAGMLLTTEVLIVEKPEEKKETPSIPEEF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_STAA3
Sequence: MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: PSBZ_MESVI
Sequence: MLAAFQLTVLALIATSFLMVIGVPVIFASPEGWVKSKNFVFSGALLWISLVFAVGILNSFVV
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.