PharMolix/UniProtQA huggingface dataset:
Protein: MUTS_BURA4
Sequence: MTTLSPEAFAGHTPMMQQYLRIKADHPDTLVFYRMGDFYELFFEDAEKAARLLDLTLTQRGASAGTPIKMAGVPHHAVEQYLAKLVKMGESVAICEQIGDPATSKGPVERKVVRVVTPGTLTDAALLSDKNDVYLLAMCTGHNKRGVAVNIGLAWLNLASGALRLAEIEPDQLGAALERIRPAEILTADGATDTVPAGAGAIKRVPAWHFDIASGTQRLCDQLDVAGLDGFGAHSLTSACGAAGALLLYAAATQGQQLRHVRSLKVENETEYIGLDPATRRNLELTETLRGTESPTLYSLLDTCCTTMGSRLLRHWLHHPPRASVAAQSRQQAIGALLDAPADASLDALRSALRQIADVERITGRLALLSARPRDLSSLRDTFAALPALRERISAIVANADALTRVDAALAPPAECLDLLTSAIAPEPAAMVRDGGVIARGYDAELDELRDISENCGQFLIDLEARERTRTGIANLRVEYNKVHGFYIEVTRGQTDKVPDDYRRRQTLKNAERYITPELKTFEDKALSAQERALARERALYDGVLQALLPFIPECQRVASALAELDVLAAFAERARTLDWVAPTFTDEIGIEIEQGRHPVVEAQVEQFIANDCRFGAERKLLLITGPNMGGKSTFMRQTALIALMAYVGSYVPAKSACFGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILNDATPQSLVLMDEIGRGTSTFDGLALAWAIARHLLAQNGCYTLFATHYFELTQLPAEFPQAANVHLSAVEHGHGIVFLHAVNEGPANQSYGLQVAQLAGVPAPVIRAARKHLAYLEQQSATQNTPQLDLFSAPPAAADELECADAPAVSAIPHPALEKLRDIDPDDLKPRDALDLLYELRTLVRSHDADGHA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: KITH_EHV2
Sequence: MAEGGAGFSSSSTSSEEAVPWSTQQPMGWEELESLGDGGGSTSADEEFQWEAMFVKSRAGSPTAEDKSRTFTLPRGRPKNEPRPERGKGKTPKKPKKPDQGATLLVGEEPRPRLGSRTRSKSRSRDKHQLPDDIYDVPNPPMLAPVDSYGNPVEQVSSSESDFEDIANIRPILRRQQPVTVKHRREPSPEPLGHPTFVHRYDKPSYDEEVCQKKDKGGRTKSKNWLRQPGVKSKLTSMKDLSGSFKSLMHIRSDGEKHKQQQRPGGSGAPGGATPRDVFNTFLGSGTCPSFKNAFFLYLEGSMGVGKTTLIRHMREINGDNVISFVEPMFYWREVYSDCVKLIYSACKPFNLGKMSTSNKVLSAQMKFMTPMKCLQTSVRRYVKANEPLQEKTAMDNWLLFDRHPLSATLVFPYLSLKNGYLAFEHFLALAANFTAHEGDIIALLCMGEEDNLKMVKLRNRKGESGVTSAHLKDLGQAFHACYCTWLLLKYLSPEDMVSVCCCDVTLNDICIMRSMSSSKVTMAKSLFNKSMFPTLMDVIQPFRSNCTIIEICLTLFMELKKVEFIVVNASEFIGDIPGVWTSIYTQSLRTQAIKTQSIDWSGLRAFSLTYNS
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: Y2116_KOCRD
Sequence: MDETTLTPDRARQRFRAGLVRPAAGMAPGHAQANLVIVPRELAFDVLLFAPRNPKPCPVLGVLDAGETTGALLPGGDIRTDVPQYVVYENGVEVARPHDITPYWREDLVTVMLGCSFTFEDALQAHGIRLAHIDQGVNVPMYRTSRRCESAGRLSGPLVVSMRPVPAARVADAVRITSRYPAVHGAPVHVGDPGALGSRTWGHRTSATPCGSPPARFPCSGRAGSRRRPRWWSRLRRSPSPTPRATCSSPTPGTPTTRCPDGARERGGRALVHPCGVRSLPTRQPQPRPAVSRGSPVTPVARRRRLWLAALTRAGRGSRPVRHPGSPAATVPPGPGRRTPAPRAPRRCAPRSGRGTPCRRASRGTPGASSRGPGPCPRAAPVRRRPPPAPGGSAGSRPTWRPRRRSPALPAPRTRCPAVSR
What are the official names of this protein?
Putative hydro-lyase KRH_21160.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: ANP1_ARATH
Sequence: MQDFFGSVRRSLVFRPSSDDDNQENQPPFPGVLADKITSCIRKSKIFIKPSFSPPPPANTVDMAPPISWRKGQLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIVRYLGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGANILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFSADIWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPTASELLKHPFVMGKHKESASTDLGSVLNNLSTPLPLQINNTKSTPDSTCDDVGDMCNFGSLNYSLVDPVKSIQNKNLWQQNDNGGDEDDMCLIDDENFLTFDGEMSSTLEKDCHLKKSCDDISDMSIALKSKFDESPGNGEKESTMSMECDQPSYSEDDDELTESKIKAFLDEKAADLKKLQTPLYEEFYNSLITFSPSCMESNLSNSKREDTARGFLKLPPKSRSPSRGPLGGSPSRATDATSCSKSPGSGGSRELNINNGGDEASQDGVSARVTDWRGLVVDTKQELSQCVALSEIEKKWKEELDQELERKRQEIMRQAGLGSSPRDRGMSRQREKSRFASPGK
What is the function of this protein?
May be involved in an oxidative stress-mediated signaling cascade that phosphorylates downstream MAP kinases MPK3 and MPK6.  May suppress auxin signaling that promotes cell cycle.  Functionally redundant to ANP2 and ANP3 in the positive regulation of cytokinesis.
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase ANP1, Arabidopsis NPK1-related kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: AIS_ECOK1
Sequence: MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRFLQCGNEIYSAIKDLQRKAPDKNIVIFTHNHCLTYIAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: VATH2_CAEBR
Sequence: MAEVAHHNIPAVDMINATSRLQLEAAEVRSNKPNWGSYFRSKMIQEDDYTLVTSYENAKSKDERDQVIAANDANGQLAKTMANLITQVAKDQNVRYVLTLFDDMLQEDKSRVEIFHKAAHRQKRTAFSQYLGILQRQDNFIVNQMSSIIAKLACFGVTRMEGQDLQYYFSFLKEQLKNSTTNEYMNTTARCLQMMLRHDEYRHEFVVTDGVQTLVTALNGKTNFQLQYQLIFSVWCLTFNADIAKKTPSLGVITALGDILSESTKEKVIRIILASFVNILNKVEEREIKREAALQMVQCKTLKTLELMDAKKYDDPDLEDDVKFLTEELTLSVHDLSSYDEYYSEVRSGRLTWSPVHKSEKFWRENAAKFNDKQYEVVKILIKLLESSSDPLILCVASHDIGEYVRHYPRGKTVVEQQQGKAAVMRLLTAEDPNVRYHALLAVQKLMVHNWEYLGKQLDSDAQGDGVAAK
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity).
What are the official names of this protein?
Probable V-type proton ATPase subunit H 2, V-ATPase subunit H 2, Vacuolar proton pump subunit H 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase H subunit family.
Protein: FENF_BACIU
Sequence: MNNLAFLFPGQGSQFVGMGKSFWNDFVLAKRLFEEASDAISMDVKKLCFDGDMTELTRTMNAQPAILTVSVIAYQVYMQEIGIKPHFLAGHSLGEYSALVCAGVLSFQEAVKLIRQRGILMQNADPEQLGTMAAITQVYIQPLQDLCTEISTEDFPVGVACMNSDQQHVISGHRQAVEFVIKKAERMGANHTYLNVSAPFHSSMMRSASEQFQTALNQYSFRDAEWPIISNVTAIPYNNGHSVREHLQTHMTMPVRWAESMHYLLLHGVTEVIEMGPKNVLVGLLKKITNHIAAYPLGQTSDLHLLSDSAERNENIVNLRKKQLNKMMIQSIIARNYNKDAKTYSNLTTPLFPQIQLLKERVERKEVELSAEELEHSIHLCQLICEAKQLPTWEQLRILK
What is the function of this protein?
Is involved in the mycosubtilin synthetase assembly, by catalyzing the transfer of malonyl groups to a specific acyl-carrier-protein domain on MycA.
What are the official names of this protein?
Malonyl CoA-acyl carrier protein transacylase, MCT.
What is the protein family that this protein belongs to?
Belongs to the FabD family.
Protein: PROTO_AGEPP
Sequence: ILGTILGLLKGL
What is the function of this protein?
Shows potent antimicrobial action against both Gram-positive and Gram-negative bacteria (MIC=25 ug/ml or 32-63 uM against E. coli, MIC=1. 7 ug/ml against P. aeruginosa, MIC=3. 1 ug/ml or 4 uM against B. subtilis, MIC=8 uM against S. epidermis, and MIC=12. 5 ug/ml or 8 uM against S. aureus) (PubMed:15225564, PubMed:23836163).  Acts by disrupting the integrity of the outer and inner bacterial membranes (Probable).  Adopts an amphipathic alpha helical conformation in membrane that is essential for the membrane disrupting activity (PubMed:23836163).  Mast cell degranulator that induces a potent chemotaxis in polymorphonucleated leukocyte (PMNL) cells (PubMed:15052574, PubMed:15225564).  Shows no or weak hemolytic activity (PubMed:15052574, PubMed:15225564).
What are the official names of this protein?
Protonectin, Agelaia-chemotactic peptide, Agelaia-CP.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Protonectin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RSMA_RHOP2
Sequence: MSAIDGLPPLRDVIKRHDLAARKSLGQNFLLDLNLTARIARAAGPLDDVTVVEIGPGPGGLTRALLATGARRVIAIERDERALGALEEIAAHYPGRLEIVCADAMEFDPRPLLGGARARIVANLPYNIATPLLIGWLCAEPWPPWYDMMVLMFQREVAQRIVACEDDDAYGRLAVLSNWRCDTGMLFDIAPSAFVPQPKVTSSVVRLVPRSAPEPCNRAALEQVAAAAFGQRRKMLRQSLKALGVDPARLAAAAGIDPTRRAETVPVSGFVAMANELIDIRDTKNTP
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IP25_SOLTU
Sequence: MAVHKEVNFVAYLLIVLGLLVLVSAMEHVDAKACTLECGNLGFGICPRSEGSPENRICTNCCAGYKGCNYYSANGAFICEGESDPKKPKACPRNCDPHIAYSKCPRSEGKSLIYPTGCTTCCTGYKGCYYFGKNGKFVCEGESDEPKANMYPAM
What are the official names of this protein?
Proteinase inhibitor type-2 P303.51, Proteinase inhibitor type II P303.51.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I20 (potato type II proteinase inhibitor) family.
Protein: TUS_CITK8
Sequence: MARYDLVERLNGTFRQTEHALATLTENLEQQPLLIARVFSLPEVTKEAEHNPLATIAVEQHLGKEAESLALRHYRHLFIQQQSENRSSKAAVRLPGVLCYQVDDATQAALENQIQHINQLKTTFERIVTVESGLPSAARFEWVHRHLPGLITLNAYRALTVIKNPATLRFGWANKHIIKNLRRDEVLAQLEKSLNTPRSVHPWTREEWQARLEREYQDIAALPQQARLKIKRPVKVQPIARVWYKGQQKQVQHACPTPLIALINTDKGMTVPDIGELLNYDADNVQHRFKPQAQPLRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_KOSOT
Sequence: MKKWLFTSESVTEGHPDKIADQVSDAILDAMLEQDPESRVAVETLVATGVAVVAGEVTTKAYVDIPRIVRDTILEIGYTRAKFGFDGETCAVLTSIDEQSPDIALGVNKSLEAKNDGKDKYDIIGAGDQGMMFGYATNETEEMMPLPIVLAHNLARRLATVRKERIVEGFRPDGKTQVTVLYEDGKPIGVKTIVVSTQHDPAMTQEEIEQLVKEHVIKAVVPEEMMLDGIETFVNPTGRFVKGGPAADTGLTGRKIIVDTYGGWIPHGGGAFSGKDPTKVDRSAHYMARYVAKNIVAAGLADRVTLQIAYAIGVAHPVSFMIDAHGTEKVALEKLEKVVKEVFDFRPAAIIDKLNLRRPIYKQVAAYGHFGRIDVEVPWEKLDAVDELKRAFNM
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_BLOFL
Sequence: MIVNSCQLNVVSVEKSIFSGVIKKIYVMGVEGELGIFPGHSPLLTLIKPGLLKIFQVYNNEYLYLSGGILEVQPTVITILADVAIRAKDLDEKKVRDSKRLSEEKIKKMRHGDVDYIKISMEISKAIAQLRLIELTKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEXA_GLUDA
Sequence: MLTRKQHELLLFIDRHLKQTGFSPSFDEMKDALNLRSKSGIHRLISALEERDFLRRRHHRARALEVLRLPETMPAATGKPPLAESGPPPVTAPATDESAAAESFVPNVIKGDFANRLAGASVATEAGAIHLPFYGRIAAGQPIEALRETGAQIEVPMNLLGHGEHYALEVAGDSMIEAGILDGDTVIIRRGDVAQNGQIVVALIDDQEVTLKRLRRRGSTIALEPANARYEPRIVPSDRVRIQGQLVGLLRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MIC60_PYRTR
Sequence: MLRASILRARPAVRPLARAARPQWHVAQRFYVDDKKNLGETAVPNPAPTTQPSSSPSNPTPVQENTIPASEVPKGPPAPDSTIGASRDAPTTQPSTTPPTGTGTASVAPDPIKPLPKKKRRRFRRFLLWLTILSGLGYAGGVWYSLVSDNFHDFFTEYIPYGEDAVAYFEEREFRRRFPGRAGEPRLHPQISGENKVTIPGRSGLTARPAKENSSDLASRGPHVSAVDDNKKQDKTESGGQQPKVSSQTPVAKEQPVQATETASSKAITPLDHLNVPSATEPVVQDVVKIVNDIITVVNADNAHDGKYNSALDKAKSELTKVVSDINAMKETLEQQAEAKVKAAHAEFDQAAKELIQRLDHQMQAQETQFKEEFENERERLSQSYKERLQSELQAAQKVYEQSLKNRLLEQSIKMQKSFTATVRERVEAEREGRLGKLNELSSSVHELEKLTAEWNSVVDANLKTQHLVVAVEAVKSALETQVVPKPFVTELAALKEIAADDPVVSAAIASINPAAYQRGIPSSALLIDRFRRVAGEVRKAALLPEDAGMASHLASLAMSKVLFKKSGLAVGADVEAVLARTEVLLEEGDLDAAAREMNGLQGWAKVLSKDWLSECRRVLEVKQALDVIATEARLNSLLID
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: O13C7_HUMAN
Sequence: MVSANQTASVTEFILLGLSAHPKLEKTFFVLILLMYLVILLGNGVLILMTVSNSHLHMPMYFFLGNLSFLDICYTTSSVPLILDSFLTPRKTISFSACAVQMFLSFAMGATECVLLSMMAFDRYVAICNPLRYPVVMSKAAYMPKAAGSWVAGSTASMVQTSLAMRLPFCGDNIINHFTCEILAVLKLACADISVNVISMGVTNVIFLGVPVLFISFSYVFIIATILRIPSAEGRKKAFSTCSAHLTVVVIFYGTILFMYGKPKSKDPLGADKQDLADKLISLFYGVVTPMLNPIIYSLRNKDVKAAVRDLIFQKCFA
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 13C7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPSA_BACSU
Sequence: MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIPFKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDPLPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDTIILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQNTLFSLEDIKRIQSHLLTILENALKHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAFTLHGLFERQAAFTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLATVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMERAFKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEQEAAAAFIKPFDLSQAPLFRAQIVKISDERHLLLVDMHHIISDGVSVNILIREFGELYNNRNLPALRIQYKDYAVWREGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSFTLDQEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVDKLELTRDMSRNPVFDAMFILQNVEKQDIDLREIKVRPANFAHHISLFDITLIATEISGSICCEMEFSTEVFLKATIERWADHFIEFLHEALSTPETSLAQINILSDKEKQKIVFEFNKTQVEFAQKDIPFHRIFEAKAEENPEHIAVIDNETEISYRLLNERANRLARTLQNRKGPKPTVAVLAKRSIDAIVGVLAVMKAGGVYIPIDAHYPKARIEYILRDSGADILLLQRELKHLISNSPESEMSHIFLDDEGSFEESNCNLNLSPAPEEPVYIIYTSGTTGAPKGVIVTYQNFTHAALAWRQIYELDRKPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEIYKIIKSQRITVMESTPALIIPVMEYVYRNQFKLPDLDILILGSDMVKAQDFKTLTDRFGQSMRIINSYGVTEATIDSSFYETSMGGECTGDNVPIGSPLPNVHMYVLSQTDQIQPIGVAGELCIGGAGVAKGYHHKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIRLLGRMDYQVKINGYRIETEEIESVLLQTGLVREAAVAVQHDKNGQAGLAAYIVPSDVNTNALRAALTKELPAYMIPAYLIPLVNMPLTLNGKLDRNALPAPNNVLSRPYTAPVNDLQKTMAYIWEDVLSMSRVGIHDSFFELGGDSIKALQVAARLAAEGWSMTIRDLFRYSTIQELCGHITPLASQADQGPAEGEAELTPIQRRFFGQVHAFHYHYNQSVMLFSEKGFNANALHLALRKITEHHDAIRMIFQRDQNGHVIQFNRGINHKDHELFGLYISDWTKASLERAHLDEKLAAEETVIQSKMNVEKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRILLEDLAAAYQQALEKKEIQLPPKTDSYLSYADGLTQIAESKQLLSEKTYWQTILDAHTAFLPKDIENVPDKLQMNSDAAAFVLSGDWTEKLLFETQQAYGTDANELLLTALGMALSEWTGHDQIVISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMGIPEPFEDQLAYRIKTTKDMLRRVPNKGTGYGLLTHIGELRHKEPEVSFNYLGQFSEEKEVETFQLSYYQPRYEIAGEREREYELDINALITDGRLHVKAVYTQVFSKHSIECFMDRFHRHLIETIEHCSQKKAREKTLSDFSNKELTLSALSSIEDLVKDL
What is the function of this protein?
This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Orn as part of the biosynthesis of the lipopeptide antibiotic lipastatin.  The Orn residue is further epimerized to the D-isomer form.  The activation sites for these amino acids consist of individual domains.
What are the official names of this protein?
Plipastatin synthase subunit A, Peptide synthase 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL1_THERP
Sequence: MPKHGKKYLEALKLVDVTRRYSPKEAVELVKKVAHADFDESIDLHIKLNIDPRHADQNVRGTVTLPHGTGRTPRVLVFAVGEAARIAEEAGADYVGSDDLIRQIEGGWLEFDAAIAMADQMGKVGPLGRILGRRGLMPNPRTGTVVRNPEDLPAVIREIKGGRVEFRNDRTGNIHLQIGRKSFTDQQLLENLYVAVDAIARARPQAVKGQFFQSMTIAPTMGPGIPLDVATTVEEARQFVT
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ASTD_ECO5E
Sequence: MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACRAARAAFPRWARLSFAERQAVVERFAGLLERNKGELTAIIARETGKPRWEAATELTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGCETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRVLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVFTAWQQLEAMGGRTLLAPRLLQAGTSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEAIRMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: HMMR_MOUSE
Sequence: MSFPKAPLKRFNDPSGCAPSPGAYDVKTSEATKGPVSFQKSQRFKNQRESQQNLNIDKDTTLLASAKKAKKSVSKKDSQKNDKDVKRLEKEIRALLQERGTQDKRIQDMESELEKTEAKLNAAVREKTSLSASNASLEKRLTELTRANELLKAKFSEDGHQKNMRALSLELMKLRNKRETKMRSMMVKQEGMELKLQATQKDLTESKGKIVQLEGKLVSIEKEKIDEKCETEKLLEYIQEISCASDQVEKCKVDIAQLEEDLKEKDREILSLKQSLEENITFSKQIEDLTVKCQLLETERDNLVSKDRERAETLSAEMQILTERLALERQEYEKLQQKELQSQSLLQQEKELSARLQQQLCSFQEEMTSEKNVFKEELKLALAELDAVQQKEEQSERLVKQLEEETKSTAEQLTRLDNLLREKEVELEKHIAAHAQAILIAQEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESYKSSTLKEIEDLKLENLTLQEKVAMAEKSVEDVQQQILTAESTNQEYARMVQDLQNRSTLKEEEIKEITSSFLEKITDLKNQLRQQDEDFRKQLEEKGKRTAEKENVMTELTMEINKWRLLYEELYEKTKPFQQQLDAFEAEKQALLNEHGATQEQLNKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRSQLVKRKQNELRLQGELDKALGIRHFDPSKAFCHASKENFTPLKEGNPNCC
What is the function of this protein?
Receptor for hyaluronic acid (HA) (PubMed:1376732).  Involved in cell motility (PubMed:1376732).  When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2/FAK1 occurs.  May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.  May act as a regulator of adipogenesis (PubMed:22666460).
What are the official names of this protein?
Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility.
What are the subcellular locations of this protein?
Cell surface. Cytoplasm. Cytoplasm, cytoskeleton, spindle.
Protein: CARB_STRP7
Sequence: MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMELSKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAATIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: SFSA_SHEPA
Sequence: MEFSPAFETGVLVQRYKRFLTDITLDNGEQVTIHCPNTGSMKNCLFPGEKVWFSTSDNPKRKYSRTWELAQTPEGHIIGINTGRANALAEEAIHAGVITELQGYHSLRREVKYGSENSRIDILLEDTKKPNCYIEVKSCTLLEEGQGYFPDAVTARGQKHLRELMEMVEQGQRAVLLFVVQHSGIKSVQAATHIDAEYAELLSKAYHKGVEIIAYSTDSSPLGASLVKSCPVRL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.