PharMolix/UniProtQA huggingface dataset:
Protein: TSH2_MOUSE
Sequence: MPRRKQQAPKRAAGYAQEEVLKEEEEIKEEEEEEEDSGSVAQHQSSNDTGTDEELETGPEQKGYFSCQNSPGSHLSNQDAENESLLSDASDQVSDVKSVCGRDVSDKKANTHPKLPSEPHNCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNSSGKNDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKLCGSVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSLADSFSSQKSANLQLPSNSRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSETPNSESLAPKPSSNSPSECTASTTELKKESKKEKGEGIEDEQGVKSEDYEDSLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPMAMGSQILQIRPNLANKLRPIAPKWKGMPLGPVPTSLALYTQVKKETEDKDEVVKQCGKESPHEEATSFSQPEGESFSKIEPPSESRKAEPCPLKEEEKPQKEKPEPLEPVSSLTNGCAPANHTPALPSINPLSALQSVLNNHLGKATEPLRSPSCSSPNSSTSPVFHKSSLHVVDKPVISPTSTRPAASVARHYLFENTDQPIDLTKSKSKRAESSQAQSCTSPPQKHALCDIADMVKVLPKATTPKPAASSRVPPMKLEIDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRMAADQQSKVEQEISRVSSAQRSPETIAGEEDTDSKFKCKLCRRTFVSKHAVKLHLSKTHSKSPEHHSQFVADVDEE
What is the function of this protein?
Probable transcriptional regulator involved in developmental processes.  May act as a transcriptional repressor (Potential).
What are the official names of this protein?
Teashirt homolog 2, SDCCAG33-like protein, Zinc finger protein 218.
What is the protein family that this protein belongs to?
Belongs to the teashirt C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DYM_DICDI
Sequence: MGVASSNTAAGGVVPGENINNDETLSNNNKNNNNNNNNNNNNNNNNNNNSSTTTNLLVAADTAIANMASFYQSTLSDDFKLLASENQLPEDLDTFMETLLFSLNFSEESNHNYVYGLLNELSKQLVSNNLKTKNFNRILMHFINKLNLFNQQLITISESMKKNKGSKQQLILDQSVEIQLYTHQQFLVNYTILIQTFSKYIIENMDHVNIIQQFTGDSENSFKTIPFDLILSILGFLSNELRDCSYDLHDVLLRFILILFSTEMYLPLPTIQENYLTDTFTVDFSFYELLAPKTNIFLNILMDTVYNNPNSPIVYSFIFNLFNNIIENKPPPSTSNSLLDSIGSAASYLLLLPLNAYKYFFPQNNATGNSMTELSTFNLLVLVQYNYPKGNPFRKILSNIQDKDFSIDLLNSNPNNHQIRISMQQLYESIIKSPSSDKNILLLYYLLQENSFFFRYVQSRTDLDNLLLPMIQILYNSFEEKPQQVNMILIIILILSQDSLFNENVHSLIVHQILWYKERLLIDVSLGGILMVVLIKSIILNLSKLRDAHLHTNCLAILANLSSNISHIHPYVANRLVKLLEILSKRYIKLKKMLNQVDSPSKINTNNSNNNVKDNTNNITQSMSSVSISDDLSLDVNQLQQIKNLENHNSSINKHHNESHNNSSFLNSPDLNLKELQSEELTTHSEFLYIVLQIINNTLTYRAYSNPHLIYSLLHQQEYFPVFLNEENLSSLSNNILNILSYFSSELKHAINGLSQQETTAETIMSFIESKSKSLPVPPPDQEGILRFKYEEESTSFEFITPYVWSIIFNYSGEKWDTKNITLFPTVDLTTIKSPSVIDANNFTPKKQLSSDQLHSPPTNTTTTTTTTTNSTSSNTILNSMPIPPPNTQLQQQNNLRNQEQNQEENGDEKDDKIEKEQTTGVELSSTEKTN
What are the official names of this protein?
Dymeclin.
What is the protein family that this protein belongs to?
Belongs to the dymeclin family.
Protein: GLMU_MARMM
Sequence: MSRSRSAIILAAGQGTRMKSKTVKVLHKVAGRPMLDWAVALAGDCGASDIVTVWGAHSPAVRDAAEALGTRTALQDPPKGTGHAVLAARAALADLSGDAIVLYADTPLITAATVARVFEALEGGASVAVLGFEPDDPAAYGRLITNEAGDLDRIVEFKDASEAERAVGLVNSGVLAAPAELLFDLLGEVGNDNANGEYYLTDVVGLARARDLRAAVVVADADEVLGVNSRADLAEAEAAFQSRMRQSMMADGVTLIAPETVFFAHDTQIARDVVIEPNVVFGPGVVIEEDVVVHAHSHIAGAHLKRGAHAGPFARLRPGAELGEGSKVGNFVEIKKSQLAEGAKVSHLTYIGDASVGANANIGAGTITCNYDGYDKHRTVIGDNAFIGSNTCLVAPVTVGDGAFTATGTIVTQDVPADALALARTPQTHKPGWAARFNAAKQARKARKDSQT
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRS1_HCMVM
Sequence: MAQRNGMSPRPPPLGRGRGAGGPSGVGSSPPSSCVPMGATSTAGTGASAAPTATPGHGVHRVEPRGPPGAPPSSGNNSNFWHGPERLLLSQIPVERQALTELEYQAMGAVWRAAFLANSTGRAMRKWSQRDAGTLLPLGRPYGFYARVTPRSQMNGVGATDLRQLSPRDAWIVLVATVVHEVDPAADPTVGDKAGHPEGLCAQDGLYLALGAGFRVFVYDLANNTLILAARDADEWFRHGAGEVVRLYRCNRLGVGTPRATLLPQPALRQTLLRAEEATALGRELRRRWAGTTVALQTPGRRLQPMVLLGAWQELAQYEPFASAPHPASLLTAVRRHLNQRLCCGWLALGAVLPARWLGCAAGPATGTTSPPAASGTETEAAGGDAPCAMAGAVGSAVTIPPQPYGGAGGSAICVPNADAHAVVGADATAAAAAAAAAPTVMVGPTAMAGPAASGTVPRAMLVVVLDELGAVFGYCPLDGHVYPLAAELSHFLRAGVLGALALGRESAPAAEAARRLLPELDREQWERPRWDALHLHPRAALWAREPHGQWEFMFREQRGDPIHDPVAFRLSDARTLGLDLTTVMTERQSQLPEKYIGFYQIRKPPWLMEQPPPPSRQTKPDAATMPPPLSAQASVSYALRYDDESWRPLSTVDDHKAWLDLDESHWVLGDSRPDDIKQRRLLKATQRRGAEIDRPMPVVPEECYDQRFTTEGHQVIPLCASEPEDDDEDPTYDELPSRPPQKHKPPDKPPRLCKTGPGPPPLPPKQRHGSTDGKVSAPRQSEHHKRQTRPPRPPPPKFGDRTAAHLSQNMRDMYLDMCTSSGHRPRPPAPPRPKKCQTHAPHHVHH
What is the function of this protein?
Acts as a transactivator along with IE2, and is required for oriLyt-dependent DNA replication in the transient transfection replication assay using native promoters.
What are the official names of this protein?
Protein IRS1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Note=Isoform IRS1-263 is predominantly nuclear.
Protein: Y670_SHESM
Sequence: MKLVIVSGRSGSGKSVALRVLEDLGYYCVDNLPLPLIGSLLEQLKGSNDLVAISVDVRNLPEQDKVLVKQLTSLPEGTELTSFFLNSSDKVLLKRYSETRRLHPLSKSRVSLQEAIKLEGKLLEPLSQQMDHYIDTSNLNIYELSDQVRQILLGSVDKELVINFESFGFKHGMPTEADFMFDVRFLPNPHWEPELRPLTGLDEPVAEFLNRQPLVNKFIWQIENLLETWLPHLERNNRSYLTIAIGCTGGQHRSVYVAEQLAKRFSNGKHKVNARHRELSHAKA
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Shewmr4_0670.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CCNL1_HUMAN
Sequence: MASGPHSTATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQDGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR
What is the function of this protein?
Involved in pre-mRNA splicing.  Functions in association with cyclin-dependent kinases (CDKs) (PubMed:18216018).  Inhibited by the CDK-specific inhibitor CDKN1A/p21 (PubMed:11980906).  May play a role in the regulation of RNA polymerase II (pol II).  May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) (PubMed:12414649, PubMed:15700036).
What are the official names of this protein?
Cyclin-L1, Cyclin-L.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin L subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm. Note=Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing.
Protein: CALB1_CHICK
Sequence: MTAETHLQGVEISAAQFFEIWHHYDSDGNGYMDGKELQNFIQELQQARKKAGLDLTPEMKAFVDQYGKATDGKIGIVELAQVLPTEENFLLFFRCQQLKSSEDFMQTWRKYDSDHSGFIDSEELKSFLKDLLQKANKQIEDSKLTEYTEIMLRMFDANNDGKLELTELARLLPVQENFLIKFQGVKMCAKEFNKAFEMYDQDGNGYIDENELDALLKDLCEKNKKELDINNLATYKKSIMALSDGGKLYRAELALILCAEEN
What is the function of this protein?
Buffers cytosolic calcium.  May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
What are the official names of this protein?
Calbindin, Calbindin D28, D-28K, Vitamin D-dependent calcium-binding protein, avian-type.
What is the protein family that this protein belongs to?
Belongs to the calbindin family.
Protein: SP0A_CLOIN
Sequence: MNNKMNVYLVDDSMEMIHSMKEALTKSDGYQVIGSATNGEQCVNELRGKHLDVLVLDLIMPKKDGISVLHDLKKNHIQVDHIICTTPFVNDLIVAGVQNYRIDYILMKPFEIEQLCDKLNFIVGYTRKEHISSNVLQVNLDDDEKERLQKLELESEITELLHEIGIPAHIKGYMYLRTAILETYLNVDFLGQITKVLYPEIAKKYATTASRVERAIRHAIEVAWNRGNIDAIDDIFGYTISASKAKPTNSEFIAMISDKLRLEHRLRNKNNVIKTFR
What is the function of this protein?
May play the central regulatory role in sporulation.  It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress.  Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process (By similarity).
What are the official names of this protein?
Stage 0 sporulation protein A homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_SHEHH
Sequence: MNNARPIRRALLSVSDKTGILEFAQALHAQGVELLSTGGTARLLADNGVPVIEVSDYTGHPEIMDGRVKTLHPKVHGGILARRGIDEIVMEQNNIKPIDLVAVNLYPFAATVAAEGCTLADAIENIDIGGPTMVRSTAKNHKDTTIIVNANDYGRVIAEMQANQGSTTLETRFDLAIAAFEHTAAYDGMIANYFGTKVPAHSKDECHEDSKFPRTYNTQLVKKQDLRYGENSHQTAAFYVDTHLDEASVATAVQLQGKALSYNNIADTDSALECVKEFDEPACVIVKHANPCGVAIGENLLEAYNRAFQTDPTSAFGGIIAFNGELDAATASAIVERQFVEVIIAPKVSQAARDVIAAKANVRVLECGQWASKTTSLDYKRVNGGLLLQDRDQGMVGIDDVKVVSKRQPTASEMKDLMFCWKVAKFVKSNAIVYAKNSMTIGVGAGQMSRVYSAKVAGIKAADEGLEVQDSVMASDAFFPFRDGIDAAAEAGISCIIQPGGSIRDEEIIAAADEHGMAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RECX_ACTP7
Sequence: MTNYTAINYLLYLLSKRDYSEQDLRRKLVQKEYSQEEIEQAIERAQANNWQSDERYCAGFIRYRSQQGIGPRRLKQELKLKGIKDWLINQELENAEIDWFILAEQVFEKKRPQVWDIKAKQKMWRFMLSRGFYNDHFSHLMDIDYNDTEYE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_RHOP5
Sequence: MPAAIRALIAGNWKMNGLKAQLAEFEAMLAGAPALADKADLLVCPPATLLHAFGQKLGNGARSFAVGAQDCHANVSGAHTGDLSAEMLVDAGASAIIVGHSERRADHGETDSVVRAKAEAAWRAGAVAIVCVGETQAERDAGQTLDVVGRQLAGSLPDGATAENTVVAYEPVWAIGTGLTPTANDVEQVHKFIRDCLTKRFGGEGAAVRILYGGSVKPSNAKELMAVPEVNGALVGGASLKAADFLAIAAGCP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMC_SHEB5
Sequence: MSAAIVNAVKQCGYFNQGQCLSCRHIQQPLAQQVAVKTQTLQQLLAPFIPANSAELFLPPITGDDSGFRNKAKMVVLGAAHEPVLGIVGPSGEAVDLCDCLLYPADMQALLHRLTRFVQQAGLPPYRVDKAKGELKFILLTRSQVRGEYLLRFVLRSHNGIERIERELPALLAEYPQIKVVSVNIQPIHMAILEGDEEIFLTENTRLEERFNHVPLFIRPKSFFQTNPQVAAQLYQTAREWVAEFSPRSLWDLFCGVGGFGLHCASNDITLTGIEIEAEAIACAQMSAQMMGLENVQFMALDSTDFAKGKSAADKPDLIIVNPPRRGIGEALCQSLSEFAPKAILYSSCNPKTLAKDLEHIQGYHLTKVQLFDLFPHSDHFEVLAMLVKD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: COQ8A_HUMAN
Sequence: MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQGQDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYVASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
What is the function of this protein?
Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144, PubMed:21296186, PubMed:25540914, PubMed:27499294).  Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:25498144, PubMed:27499294).  Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (PubMed:25498144, PubMed:27499294).  Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144).
What are the official names of this protein?
Atypical kinase COQ8A, mitochondrial, Chaperone activity of bc1 complex-like, Chaperone-ABC1-like, Coenzyme Q protein 8A, aarF domain-containing protein kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single-pass membrane protein.
Protein: PYRB_VIBPA
Sequence: MANSLYQKHIISIPELSREELELIVETAGNLKKEPRPELIKNKVVASCFFEPSTRTRLSFETAIQRIGGDVIGFDNDGNTSLAKKGETLSDSVQVISSYVDAFVMRHPQEGAARLASEFSNGVPVINAGDGANQHPTQTLLDLYTIAETQGRLDNLNVAFVGDLKYGRTVHSLTQALAKFNNIRFYFVAPDALAMPEYICEELDEAGIEYSLHTEMEAVIPELDILYMTRVQKERFDESEYAHIKSAYILTAALLKGARENLKVLHPLPRVDEITTDVDKTPHAYYFQQAQNGVYARQALLALVLNETL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: COBS_THEVO
Sequence: MMISGLRSSFSFFTLVPSRQKDIGNPITFLPLVVTVGALIGDSILYITWQFSHLIASFLSISSIIIYNGLNHFDATADLGDALMVRDKSRIPEVIKDHHVGAGGIFAVIFVYGIAVLSLARSTLYIGLVGILIGQVVSGSSMMISLIGSQPFVPGLADYFISLFRKHSVGYTIEFLAIPIIVSFIFSPLYVVIVALNLLIVQLTKTMISRRFGGINGDVIGFLGEFSRSLFIFMLIIIAHYNVASTYDIFSKMLSSFTS
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRE3_STAAU
Sequence: MSYSIVRVSKVKSGTNTTGIQKHVQRENNNYENEDIDHSKTYLNYDLVNANKQNFNNLIDEKIEQNYTGKRKIRTDAIKHIDGLITSDNDFFDNQTPEDTKQFFEYAKEFLEQEYGKDNLLYATVHMDEKTPHMHYGVVPITDDGRLSAKEVVGNKKALTAFQDRFNEHVKQRGYGLERGQSRQVTNAKHEQISQYKQKTEYHKQEYERESQKTDHIKQKNDKLMQEYQKSLNTLKKPINVPYEQETEKVGGLFSKEIQEAGNVVISQKDFNEFQKQIKAAQDISEDYEYIKSGRALDDKDKEIREKDDLLNKAVERIENADDNFNQLYENAKPLKENIEIALKLLKILLKELERVLGRNTFAERVNKLTEDEPKLNGLAGNLDKKMNPELYSEQEQQQEQQKNQKRDRGMHL
What is the function of this protein?
The interaction of the RSA site and the PRE protein may not only serves a function in plasmid maintenance, but may also contributes to the distribution of small antibiotic resistance plasmids among Gram-positive bacteria.
What are the official names of this protein?
Plasmid recombination enzyme type 3, Mobilization protein, Plasmid recombinase.
What is the protein family that this protein belongs to?
Belongs to the plasmid mobilization pre family.
Protein: ZNTB_SALCH
Sequence: MEAIKGSDVNVPDAVFAWLLDGHGGVKPLEDNDVIDSQHPCWLHLNYTHPDSARWLASTPLLPNNVRDALAGESSRPRVSRMGEGTLITLRCINGSTDERPDQLVAMRLYMDERFIVSTRQRKVLALDDVVSDLQEGTGPVDCGGWLVDVCDALTDHASEFIEELHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDHRRRMQDIADRLGRGLDEIDACIARTGIMADEIAQVMQESLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWRFGFSLFCILLVVLIGGVTLWLHRSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSAK_HORVU
Sequence: MASQLSAMTSVPQFHGLRTYSSPRSMATLPSLRRRRSQGIRCDYIGSSTNLIMVTTTTLMLFAGRFGLAPSANRKATAGLKLEARESGLQTGDPAGFTLADTLACGAVGHIMGVGIVLGLKNTGVLDQIIG
What are the official names of this protein?
Photosystem I reaction center subunit psaK, chloroplastic, Light-harvesting complex I 7 kDa protein, PSI-K, Photosystem I subunit X.
What is the protein family that this protein belongs to?
Belongs to the PsaG/PsaK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS9_BURTA
Sequence: MIGNWNYGTGRRKSAVARVFIKAGKGDIIVNGKPIADYFSRETSLMIVRQPLELTNHAQTFDIKVNVTGGGETGQAGAVRHGITRALIDYDATLKPSLSNAGFVTRDAREVERKKVGLHKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: TILS_THEMA
Sequence: MLEEGEHVLVAVSGGIDSMTLLYVLRKFSPLLKIKITAAHLDHRIRESSRRDREFVERICRQWNIPVETSEVDVPSLWKDSGKTLEEIAREVRYDFLKRTAKKVGASKIALAHHKNDLLETVVHRLIRGTGPLGLACISPKREEFIRPFLVFKRSEIEEYARKNNVPYVVDETNYNVKYTRNFIRHRIVPLMKELNPTVEDAVYRLVSVTHLLRNFVERTVQDFVERNVYFYKDYAVFVEPEDLFLFLEVTRWVLKEMYGRVPEYEKLIGTLKSKRVELWSGIFVERSFGYVAVGKTVFKKKYRVEVKGDMLEMEGFKIRVVNNRNDMKFWVRNRKEGDRIIVNGRERKLKDVFIEKKVPTFYRDRVPLLVDEEDRVLWVPGIARSDFLPEDVVVELLEYPVGYVKGGTYFEQV
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_MYCBT
Sequence: MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQLTGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESGASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASLAFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPTAWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADAHRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRVLVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRACRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLETLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: LUXS_EDWI9
Sequence: MPLLDSFTVDHTRMAAPAVRIAKNMTTPHGDQITVFDLRFCRPNNAILPERGIHTLEHLFAGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEARVAAAWKAAMEDVLRVSDQRSIPELNEFQCGTYSMHSLEEAHQIARQILASGIGINHNDTLALSAEQLTHLHP
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: NRAM_I85A8
Sequence: MNPNQKILFASATAIVIGTIAVLIGIVNLGLNIGLHLKPSCNCSRSQPEATNASQTIINNYYNKTNITQISNTNIQVEERASREFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGRARMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLTGTAKHIEECSCYGEQARVTCTCRDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGGNTWLGRTISTASRSGYEMLKVPNALTDDRSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDRVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: CENPA_YEAST
Sequence: MSSKQQWVSSAIQSDSSGRSLSNVNRLAGDQQSINDRALSLLQRTRATKNLFPRREERRRYESSKSDLDIETDYEDQAGNLEIETENEEEAEMETEVPAPVRTHSYALDRYVRQKRREKQRKQSLKRVEKKYTPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI
What is the function of this protein?
Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes.  Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore.  Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May serve as an epigenetic mark that propagates centromere identity through replication and cell division.  Required for functional chromatin architecture at the yeast 2-micron circle partitioning locus and promotes equal plasmid segregation.
What are the official names of this protein?
Histone H3-like centromeric protein CSE4, CENP-A homolog, CENPA homolog, Chromosome segregation protein 4.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres.