PharMolix/UniProtQA huggingface dataset:
Protein: DTDA_METPE
Sequence: MKITLVNSRLDPAGVTIREQIQVLLADPEYQREGIDWEFLEIDGRLIHQERIDTGLNSDLLIFLSRHTSRRPVPVLTVHPTGNPGEALLGGEAGSFAPAAPGWMQAVLQNLVRLVPDGYQASYEVTHHGPTTLSTPSFFVEIGSTDHEWSDPVAGAAVAEAVLTAAPVDPISLIGFGGTHYAPRETAVALETRGAFGHILHSREIGGLTGSLLAKIATAAEAEAVYIDRKAIDRPALDHLYALLEETDLPVLGEKELHQIGSLSWQEYRSLRQIAGDAAPGAHLVIGTLPGGGTPVTATVPADLLAQAISADQGRVMTAIGRMPVVGLTGRGGLLLPIIITYERYRSQIIHDLITLCVKTIREEQHAVIDGDRLIIKKERFDPGLAASLGVPPGALFGMLKGGQAVRVGDQVIKPEMVRSCTVTAIHLRGLERYT
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: LUXS_ENTFA
Sequence: MARVESFELDHNTVKAPYVRLAGTEQNGDALVEKYDLRFLQPNKDALPTGALHTLEHLLAVNMRDELKGIIDISPMGCRTGFYMIMWDQHSPQEIRDALVNVLNKVINTEVVPAVSAKECGNYKDHSLFAAKEYAKIVLDQGISLDPFERIL
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: MDPD_EMENI
Sequence: MTHFPVNIASDKQEFDPERWAKTPTTESSVNGENGTAPTSGLPSRHPSTGISVLIVGAGMGGLMTALECWRKGHDVAGILERSEGPVYSGDIIVMQPSAVSIIRHWPDMLHDMKAEQVHAVVSYETHDGRHIYGPTVPSFNDPEHLETRKGPFVAPAQVRRKFYRMLLRQVARCGLRVEYGKTVKSYFEDEKDGKGGVIIATTGEAEVRVADIVVAADGLKSPSEILIAGQHVPPRSSGLSIYRTAFPKDLAMQNELVRKRWSDSPPIWEYWLGPGMYLGVFVGDDIISFGFTPRDDIVEGTATESWEPDTDPETVAQAMLSGAGDWDPAVLALIRSAPKGAIVHWPLLWRDLRREWTSPAGRVVQVGDSAHSFIPTSGNGGSQALEDAITLATCLQLAGSSQRAYLGTKIYNLLRYERVSCAQKMSFVNSQLKTGTDWDAIWKDPAKIRTRFPKWIFQHDPEAYAYEKFGEAFAHLLDGREFVNTNYPPGHEFRAWTVEEVWRNIADGKRVEDLLDGDWS
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative (PubMed:20139316, PubMed:21351751, PubMed:22730213).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG (PubMed:20139316).  The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG (PubMed:20139316).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (PubMed:20139316).  The next step is performed by the anthrone oxygenase mdpH that catalyzes the oxidation of emodinanthrone to emodin (By similarity).  Emodin is further modified to yield monodictyphenone via several steps involving mdpB, mdpC mdpJ, mdpK and mdpL (PubMed:20139316, PubMed:21351751).  These enzymes with xptA, xptB and xptC are also proposed to be involved in the synthesis of shamixanthone from emodin (PubMed:22730213).  Especially, direct reduction of emodin by the short chain dehydrogenase mdpC followed by dehydration catalyzed by the scytalone dehydratase-like protein mdpB gives loss of oxygen and formation of chrysophanol intermediate in two simple steps (PubMed:22730213).
What are the official names of this protein?
FAD-dependent monooxygenase mdpD, Monodictyphenone synthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: HIS4_CHLP8
Sequence: MLIIPAIDIKEGKCVRLTRGDFAQKKIYLDNPADMAIIWRKQNAKMLHVVDLDAALTGEMVNFEKIREIVELLDIPIQVGGGIRSVEAVEKYLSIGVSRVVIGSAAVTNPSLVADLLKKYRPSQIVVGIDAEHGVPKIKGWTESSNMQDYELALEMKKLGVERIIYTDITRDGMLQGVGYETTKRFAEKAGMKITASGGVSTSDDLHKLRSLERFGVDSVIIGKALYECNFPCQELWYAYEQDLGIDGEFSTARKKECCR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEP55_MOUSE
Sequence: MSSRSPKDLIKSKWGSRPSSSKSDTALEKFKGEIAAFKTSLDEITSGKGKMAEKGRSRLLEKIQVLEAEREKNVYYLLEKDKEIQRLKDHLRSRYSSSSLFEQLEEKTKECEKKQQLLESLSKETDVLKNQLSATTKRLSELESKASTLHLSQSMPANCFNSSMNSIHEKEMQLKDALEKNQQWLVYDQQREAYVKGLLAKIFELEKRTETAAASLTQQMKKIESEGYLQVEKQKYDHLLENAKKDLEVERQAVTQLRLELDEFRRKYEEARKEVEDLNQLLSSQRKADIQHLEEDKQKTERIQKLREESSIFKGKLEEERKRSEELLSQVRILYDSLLKHQEEQARVALLEQQMQACTLDFENEKLDRQNMQHQLYVILKELRKAKSQITQLESLKQLHGFTITEQPFPLQREPESRVKATSPKSPSAALNDSLVECPKCSVQYPATEHRDLLVHVEYCMK
What is the function of this protein?
Plays a role in mitotic exit and cytokinesis.  Recruits PDCD6IP and TSG101 to midbody during cytokinesis.  Required for successful completion of cytokinesis.  Not required for microtubule nucleation.  Plays a role in the development of the brain and kidney.
What are the official names of this protein?
Centrosomal protein of 55 kDa, Cep55.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody, Midbody ring. Note=Present at the centrosomes at interphase. A small portion is associated preferentially with the mother centriole, whereas the majority localizes to the pericentriolar material. During mitosis, loses affinity for the centrosome at the onset of prophase and diffuses throughout the cell. This dissociation from the centrosome is phosphorylation-dependent. May remain localized at the centrosome during mitosis in certain cell types. Appears at the cleavage furrow in late anaphase and in the midbody in cytokinesis.
Protein: PSBZ_EUGST
Sequence: NGWNENKNFILLGAVTWAILVFIVGSLNSYVI
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: RL7A_SULIY
Sequence: MSKASYVKFEVPQDLADKVLEAVRKAKESGKIKKGTNETTKAVERGQAKLVVIAEDVQPEEIVAHLPLLCDEKKIPYVYVSSKKALGEACGLQVATASAAILEPGEAKDLVDEIVKRVNEIKGKTSS
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_DESRM
Sequence: MPKGILGKKIGMTQIFNEAGVAIPVTVVEAGPCLVVQKRTPENDGYSAIQLGFGVKRENLLNKPTKGHLNKAGVRPVRFLRELKVDDLEAFQVGQEIKADIFAEGEKVDVVGTSKGKGFAGGIKRHNFHRGPMAHGSKYHRRPGSSAAKGPARTFKGRKLPGHYGVERVTVQNLQVVKVDPERNLLAIKGAVPGPRGGLLLVKNSVKVK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: STC2_MACNE
Sequence: MCAERLGHFMTLALVLATIDPARGTDATNPPEGPQDRSSQQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIRGLHGICMTFLHNAGKFDAQGKSFIKDALKCKAHALRHRFGCISRKCPAIREMVFQLQRECYLKHDLCAAAQENTRVIVEMIHFKDLLLHEPYVDLVNLLLTCGEEVKEAITHSVQVQCEQNWGSLCSILSFCTSAIQRPPTAPPERQPQVDRAKLSRAHHGEAGHHLPEPSSRETGRGAKGERGSKSHPNAHARGRVGGLGAQGPSGSSEWEDEQSEYSDIRR
What is the function of this protein?
Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
What are the official names of this protein?
Stanniocalcin-2, STC-2.
What is the protein family that this protein belongs to?
Belongs to the stanniocalcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDC_PARPJ
Sequence: MDIKRTVLWVIFFMSAVMLFDNWQRDHGRPSMFFPSATPTKTVGSAAPGTTTPGTQPADLPATNAAAPGNAPAATQSQLVKFNTDVYSGEIDTRGGTLSKLSLVNKGDGKQPDLVITLFDRTANHTYLARTGLLGGDFPNHNDIYTPLPNQQHDLTGDEKSFQLSFESPVKGGVKVIKTYTFTRGSYVIGVDTKIQNVGTAPVTPSVYMELVRDDQPVETPRFSHTFIGPAVYTDQHHFQKMTFGDIDKNKQDYATSADNGWIAMVQHYFASAWIPQQGVKRDIYVEKIDPALYRVGVKEPVPTIAPGQTVDVSARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHSYVGNWGWSIVLLTLLIKAVFFPLSAASYKSMARMKAITPRMQALRERFKGDPQKMNSALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLSSVEMRGAPWILWIHDLSQQDPFFILPVLMAVSMFLQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRMMGQTKAKAA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METK_MYCCT
Sequence: MNQNIEKRLFTSESVSEGHPDKICDQISDAILDEVLKQDKNAKVACEVFTTTNYLLIGGQISSTAIVDYEQVARDVLKKIGYVDDAYGINANTCKIDIKIESQSPDIAQGVELSNDQIGAGDQGIMFGYATNESKTYLPLAITIAHELVYNATSQRKKGLFKWARPDMKSQVTIDYTNINNPKIDTILMSIQHDPNYNEIEFKKYIKENIMDLVAKEFNLNTDFKVLINPTGRFVIGGPQGDTGLTGRKIIADTYGGYSRHGGGAFSGKDSTKVDRSAAYMCRYVAKNLVAAGLADKIEIQVSYAIGISQPISIFIETFNTHKVDLNTIYKAVYENFDFSVSSMIKTLDLKKPIFFKTSKYGHFGKKDLSWEKLDKIEVLKEYKKCS
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_CORJK
Sequence: MTPAELSELITETARTTLDAHGLDSSVVPESATVERPRNPEHGDYATNIAMQVAKKAGTNPREFGTWLAESLGAHEGIDEATVAGPGFINIRLAAAAQGKIVEDILTVGANFGHGDELAGAAINLEFVSANPTGPIHLGGTRWAAVGDSLGRVLNARGAKVTREYYFNDHGAQIDRFARSLVAAAKGEPTPEDGYGGDYIQDIASQIVEANPDWQKLGADEAQELFRSQGVELMFAHIKRTLAEFGTEFDVYFHENSLFESGAVEAAIQKIKDNGNLYEADGAWWLRSTNFGDDKDRVVIKSDGNAAYIAGDIAYVADKFDRGHNLCIYMLGADHHGYIARLRAAAAAMGYDPQQVEVLIGQLVNLVKDGKAVRMSKRAGTVITLDDLVEAIGVDAARYAMIRSSVDSSLDIDMDLWASKSNDNPVFYVQYAHARLCSLARKAEDLGVTREGADLSLLTHDREGDLIRTLGEFPAVVKTAAELREPHRVARYAESLAGTFHRFYDACQILPKPSDDEQTVAENKALFAARLSLAAASRQTLANALELLGVAAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_RHOP5
Sequence: MSTIDDLPPLREVIQRHDLSARKSLGQNFLLDLNLTTRIARAAGPLEDSTVIEVGPGPGGLTRALLALGAKRVIAIERDERALGALAEISAHYPGRLDIVCADAMTYDPRPLLGGARAKIVANLPYNIATPLLIGWLETDPWPPWYDCLVLMFQREVAERIVATEDDEAYGRLGVLANWRAQTKMLFDISPAAFVPPPKVTSSVVRLIPRDEPEPCNRRMLEQVTAAAFGQRRKMLRQSLKSLGVDPARLAAAAGVEPTRRAETIPVAGFVAMARELANIRGIKSEC
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPTB_SALTY
Sequence: MRYIKSMTQQKLSFLLALYIGLFMNCAVFYRRFGSYAQEFTIWKGLSAVVELGATVLVTFFLLRLLSLFGRRVWRVLATLVVLFSAGASYYMTFLNVVIGYGIIASVMTTDIDLSKEVVGLHFVLWLIAVSVLPLIFIWSNHCRYTLLRQLRTPGQRFRSAAVVVLAGVMVWAPIRLLDIQQKKVERATGIDLPSYGGVVANSYLPSNWLSALGLYAWAQVDESSDNNSLINPARKFTYVAPKDGDDTYVVFIIGETTRWDHMGIFGYERNTTPKLAQEKNLAAFRGYSCDTATKLSLRCMFVREGGADNNPQRTLKEQNVFAVLKQLGFSSDLYAMQSEMWFYSNTMADNISYREQIGAEPRNRGKTVDDMLLIDEMQNSLAQNPEGKHLIILHTKGSHFNYTQRYPRSYAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFITSVFDQLRDKKAIVFYAADHGESINEREHLHGTPRNMAPPEQFRVPMLVWMSDKYLASPQHAQMFAHLKQQAEIKVPRRHVELYDTIMGCLGYTSPNGGINQNNNWCHIPDVQKVAAK
What is the function of this protein?
Catalyzes the addition of a phosphoethanolamine (pEtN) moiety to the outer 3-deoxy-D-manno-octulosonic acid (Kdo) residue of a Kdo(2)-lipid A.  Phosphatidylethanolamines with one unsaturated acyl group functions as pEtN donors and the reaction releases diacylglycerol.
What are the official names of this protein?
Kdo(2)-lipid A phosphoethanolamine 7''-transferase, Phosphoethanolamine transferase EptB.
What is the protein family that this protein belongs to?
Belongs to the phosphoethanolamine transferase family. EptB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MMPS3_MYCBO
Sequence: MSGPNPPGREPDEPESEPVSDTGDERASGNHLPPVAGGGDKLPSDQTGETDAYSRAYSAPESEHVTGGPYVPADLRLYDYDDYEESSDLDDELAAPRWPWVVGVAAIIAAVALVVSVSLLVTRPHTSKLATGDTTSSAPPVQDEITTTKPAPPPPPPAPPPTTEIPTATETQTVTVTPPPPPPPATTTAPPPATTTTAAAPPPTTTTPTGPRQVTYSVTGTKAPGDIISVTYVDAAGRRRTQHNVYIPWSMTVTPISQSDVGSVEASSLFRVSKLNCSITTSDGTVLSSNSNDGPQTSC
What are the official names of this protein?
Probable transport accessory protein MmpS3.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RXRG_CHICK
Sequence: MYGNYPHFIKFPAGFGNSPVHASSTSVSPSSSLSVGSTVDGHHNYLEAPTNASRALPSPMNTIGSPVNALGSPYRVIASSIGSHPVALSSSAPGMNFVTHSPQPNVLNNVSSSEDIKPLPGLPGIGNMNYPSTSPGSLAKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQGSRERSENEAESTSGGSEDMPVERILEAELAVEPKTEAYSDVNTESSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSSPSEVESLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLETPLQVT
What is the function of this protein?
Receptor for retinoic acid.  Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes.  The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5.  The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).
What are the official names of this protein?
Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCP_PYRFU
Sequence: MKVLVTGFEPFGGEKINPTERIAKDLDGIKIGDAQVFGRVLPVVFGKAKEVLEKTLEEIKPDIAIHVGLAPGRSAISIERIAVNAIDARIPDNEGKKIEDEPIVPGAPTAYFSTLPIKKIMKKLHERGIPAYISNSAGLYLCNYVMYLSLHHSATKGYPKMSGFIHVPYIPEQIIDKIGKGQVPPSMCYEMELEAVKVAIEVALEELL
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_PSET1
Sequence: MIQSLLTQFGEPLTRVENAITALQQGQGVLVVDDENRENEGDFVFSAEHLTTAQMAEMIREGSGIVCLCMGEERIKQLDLPQMVTHNTSQNNTAYTITIEAKEGVTTGVSAADRVTTIKAATADNAKPEDLSRPGHVFGLKAKTGGVLVRRGHTEASVDLMQLAGLKPFGVICELTNPDGSMARLPEVSGYANKHNMPVVSIEDLVQYIQIAQQKVS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: LPXB_BLOPB
Sequence: MSSIVPSMHNNRTIIIGIVAGEASGDILGAGLIRTLKKYLKKVRFFGIGGPCMQSEDMKSWYNIEELSVMGFAEIVMKLPRLLYIRRNLARRFINLKPDVFIGIDSPDFNISLENRLKKRGIRTIHYVSPSVWAWRKKRIFALKKATDNILVILPFEKKIYDHFNIPCQFIGHSLADQIPLNPNKVSARQKLGIPHDVYCLAVLPGSRIREIKMLAHDFLVCAKLLKNNFPNLEILVPLTNQTSIKKFISVASTSVKYRVLSNQSAWEIMMAADASLVTAGTATLECMLVKCPMVVAYRMHPLTFMLAKHFINIPWISLPNLLAGHELVKEFIQNNCRPENLAQTLINLLNNNNQHIVLKKKFRQLHHSIRCNADEQAAYAVLRLIK
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RBBP5_MOUSE
Sequence: MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVPSSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSTKGKVQAELSQSLAAGGAISELL
What is the function of this protein?
In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (PubMed:21335234).  Does not affect ES cell self-renewal (PubMed:21335234).  Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters (By similarity).  As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3 (By similarity).  Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (By similarity).  In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (By similarity).
What are the official names of this protein?
Retinoblastoma-binding protein 5, RBBP-5.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCT14_ARATH
Sequence: MAGVLAGDCSFGESGVSSYSRNSNEKQDEVARWYFGRKEIEENSPSRLDSIDLKKETYLRKSYCTFLQDLGMRLKVPQVTIATAIIFCHRFFIRQSHARNDRRTIATVCMFLAGKVEETPRPLKDVIVVSYEIIHKKDPTTAQKIKQKEVYEQQKELILNGEKIVLSTLGFDFNVYHPYKPLVEAIKKFKVAQNALAQVAWNFVNDGLRTSLCLQFKPHHIAAGAIFLAAKFLKVKLPSDGEKVWWQEFDVTPRQLEDVSNQMLELYEQNRVPASQVSEVESSVGGGSAHHVGSRPSARLTHEHSNSDNLGGSTKATQNRSNDNGSGEAGSVITEQKGERDTETKDSMHTESHPAHKSRSGVEAPGEDKIEKAGAHFPEDDKSRIVGTADVTVSQSPKDIKMFRDKVKAKLEAKKVQGEKTRKKDLVDEDDLIERELEDVELAVEDDKDIQNKSSMGTEHGEILDGNNLVVNTEEGEMIDDVSSTMPSRKRKMESPCEKQLGEGKRRHDNSENVEEGQKTNPGGSSHSYGDREPRRHSQER
What are the official names of this protein?
Cyclin-T1-4, CycT1;4, Protein AtCycT-like2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin T subfamily.
Protein: CYSH_XANC5
Sequence: MTALPAASITSSAFDDLDALNAQLEGLHADQRVAWALQHGPQNAALSSSFGAQSAVTLHLLSQQRPDIPVILIDTGYLFPETYRFADALTERLKLNLKVYRPLVSRAWMEARHGRLWEQGMVGIDQYNNLRKVEPMRRALDELEVGTWFTGLRRSQSGGRAQTPIVQKRGERYKISPIADWTDRDVWQYLQAHDLPYHPLWEQGYVSIGDFHTTRRWEPGMREEDTRFFGLKRECGIHEDI
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS28_RAT
Sequence: MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S28.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: SSRP_CLOBB
Sequence: MVRKKSSNTLAENRKARHEYFIEETIEAGIALVGTEVKSIRNGRANLKESYADIRNGEIFILSMHISPYEQGNIFNVEPLREKKLLLHKSEIHRLAGLVSRDGYTLIPLTLYLKAGKVKVALGICKGKKDYDKRDSMLEKAHNREMQRALKERSRY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.