PharMolix/UniProtQA huggingface dataset:
Protein: ENO_ECOLU
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RSMJ_HAEIE
Sequence: MAHSQVGIQLISESTEKTLAELTALCAEHNIIHHEKSPLALVQTDERLELRKLDEPKLGAVYVDFVGGTMAHRRKFGGGRGEAVAKAVGIKGSELPTVIDATAGLGRDAFVLASIGCQVRLVERHPVVFLLLQDGLNRAYQDEEIGEMLQQNLCLLNVHHINELDPNSDYADVVYLDPMYPHKQKSALVKKEMRVFQHLVGADLDADELLLPALQLAKKRVVVKRPDYAEFLCGKQPHFSRETKNHRFDIYMGASQC
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG108_VACCC
Sequence: MAAVKTPVIVVPVIDRPPSETFPNVHEHINDQKFDDVKDNEVMPEKRNVVVVKDDPDHYKDYAFIQWTGGNIRNDDKYTHFFSGFCNTMCTEETKRNIARHLALWDSNFFTELENKKVEYVVIVENDNVIEDITFLRPVLKAMHDKKIDILQMREIITGNKVKTELVMDKNHTIFTYTGGYDVSLSAYIIRVTTALNIVDEIIKSGGLSSGFYFEIARIENEMKINRQILDNAAKYVEHDPRLVAEHRFENMKPNFWSRIGTAAAKRYPGVMYAFTTPLISFFGLFDINVIGLIVILFIMFMLIFNVKSKLLWFLTGTFVTAFI
What is the function of this protein?
Envelope protein that binds to heparan sulfate on the cell surface and might provide virion attachment to target cell.
What are the official names of this protein?
Envelope protein H3, Ag35, Virion envelope protein p35.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG108 family.
Protein: B3GT6_MOUSE
Sequence: MKVFRRAWRHRVALGLGGLAFCGTTLLYLARCASEGETPSASGAARPRAKAFLAVLVASAPRAVERRTAVRSTWLAPERRGGPEDVWARFAVGTGGLGSEERRALELEQAQHGDLLLLPALRDAYENLTAKVLAMLTWLDERVDFEFVLKADDDSFARLDAILVDLRAREPARRRRLYWGFFSGRGRVKPGGRWREAAWQLCDYYLPYALGGGYVLSADLVHYLRLSREYLRAWHSEDVSLGTWLAPVDVQREHDPRFDTEYKSRGCNNQYLVTHKQSPEDMLEKQQMLLHEGRLCKHEVQLRLSYVYDWSAPPSQCCQRKEGVP
What is the function of this protein?
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue.  Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate.  Has no activity towards substrates with terminal glucosamine or galactosamine residues.
What are the official names of this protein?
Beta-1,3-galactosyltransferase 6, Beta-1,3-GalTase 6, Beta3Gal-T6, Beta3GalT6, GAG GalTII, Galactosyltransferase II, Galactosylxylosylprotein 3-beta-galactosyltransferase, UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: PB2_I82A3
Sequence: MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIMEMIPKRNEQGQTLWSNTNDAGSDRVMVSPLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKIAPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVEREEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEMSLRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQDPTMLYNKMEFEPFQSLIPKAARGQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: IMDH_PYRHO
Sequence: MGKFVEKLEKAIKGYTFDDVLLIPQATEVEPKDVDVSTRITPNVKLNIPILSAAMDTVTEWEMAVAMAREGGLGVIHRNMGIEEQVEQVKRVKRAERLIVEDVITIAPDETVDFALFLMEKHGIDGLPVVEDEKVVGIITKKDIAAREGKLVKELMTKEVITVPESIEVEEALKIMIENRIDRLPVVDERGKLVGLITMSDLVARKKYKNAVRDENGELLVAAAVSPFDIKRAIELDKAGVDVIVVDTAHAHNLKAIKSMKEMRQKVDADFIVGNIANPKAVDDLTFADAVKVGIGPGSICTTRIVAGVGVPQITAVAMVADRAQEYGLYVIADGGIRYSGDIVKAIAAGADAVMLGNLLAGTKEAPGKEVIINGRKYKQYRGMGSLGAMMKGGAERYYQGGYMKTRKFVPEGVEGVVPYRGTVSEVLYQLVGGLKAGMGYVGARNIRELKEKGEFVIITHAGIKESHPHDIIITNEAPNYPLEKF
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: BDG1_ARATH
Sequence: MGFSRSLNRTVGVFVFFILDIVDFLLCFTYKTLDFFFESEWKPCYCCPPPEAKPISAGGNRGGKMIVSERSGDYSKVVSLTRTKIYLDEISDTLYSRPSLLTKLTKLVKCFKKDVVKCCDESKKRSPSTKKTLLTVNSTVVEKLQRTPRWSDCHCTFCTSWLSSSNQSLFVNVQQPTDNKAQENVVFIHGFLSSSTFWTETLFPNFSDSAKSNYRFLAVDLLGYGKSPKPNDSLYTLKEHLEMIERSVISQFRLKTFHLVAHSLGCILALALAVKHPGAIKSLTLLAPPYYSVPKGVQGTQYVMRRLAPKEVWPPMAFGASVASWYEHISRTVSLVLCKNHHLLEFLTRLLTRNRMRTYLIEGFLCHTHNASWHTLHNIIFGSGSKVEAYLDHVRDNVDCEVAVFHGGRDELIPVECSYGVKRKVPRARIHVVPDKDHITIVVGRQKEFARELELIWRRSTTPQLHSIN
What is the function of this protein?
Required for infection by the pathogenic necrotrophic fungus Botrytis cinerea, probably by regulating structural traits of the cuticle.
What are the official names of this protein?
Probable lysophospholipase BODYGUARD 1, AtBDG1, Protein 9-cis epoxycarotenoid dioxygenase defective 1, Protein COOL BREATH 5.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Secreted, cell wall. Note=Polar localization with accumulation in epidermis outermost cell wall.
Protein: GSA_METJA
Sequence: MALKMDKSKELFEEAKKYLVGGVNSPVRYFKPYPFFVEKAKDCYLFDVDGNCYIDYCLAYGPMVLGHANDAVIKAVKEQLELGSAYGCPTEKEIILAKEVVKRVPCAEMVRFVNSGTEATMSAIRLARGVTGRKKIIKFDGAYHGAHDYVLVKSGSGALTHGHPNSPGIPEETTKNTILIPFNDEDAVKKAINENKDEIACIIVEPIMGNVGCILPKEGYLEFLREITEENDILLIFDEVITGFRLAKGGAQEYFGVVPDIATLGKILGGGFPIGAIVGRRELMEQFSPLGAIYQAGTFNGNPISITAGIATLKQLDDRFYKETARTAKILADTLRELADKHNIKAKVYNIASMFQIYFNDKEVVNYEIAKQSDTEKFMKYFWRLLEKGVFVPPSQFECCFTSIKHDDEVVDKTIKAMEDVFEGLE
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD63_FELCA
Sequence: MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLRQTIVQGATPGSLLPVVIIAVGAFLFLVAFVGCCGACKENYCLMVTFAIFLSLIMLVEVAVAIAGYVFRDKVMSEFNKDFRQQMQNYPKNNHTVSIVDRMQEDFKCCGAANYTDWGSIPLMSKARVPDSCCVNVTQGCGISFKVKEIHEEGCVEKIGGWLRSNVLVVAAAALGIAFVEVLGIIFACCLVKSIRSGYEVM
What is the function of this protein?
Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades.  Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases.  Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2.  Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2.  Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes.  Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking.  May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli (By similarity).
What are the official names of this protein?
CD63 antigen.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endosome, multivesicular body. Melanosome. Secreted, extracellular exosome. Cell surface. Note=Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules. Detected in a subset of pre-melanosomes. Detected on intralumenal vesicles (ILVs) within multivesicular bodies.
Protein: ATPD_BURP6
Sequence: MAELATIARPYAEALFRVAEGGDISAWSTLVQELAQVAQLPEVLSVASSPKVSRTQVAELLLAALKSPLASGAQAKNFVQMLVDNHRIALLPEIAVQFEALKNAREGAADVQIVSAFPLEGAQLAELVTSLERKFKRKLKPAVEVDSSLIGGVRVTVGDEVLDTSVRARLAGMQAALTA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TOLB_DICD3
Sequence: MKQALKIALSFLMLWTAVLHAEVRIEITQGVDSARPIGVVPFKSTGGAVPEEIGSIVAADLRNSGKFNPIDPSRMPQQPGSAAEVTPAAWTALGIDAVIVGQVQPTADGYMVSYQLVDTSGSAGSVLAQNQFKVTKQWLRYAAHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQYPYELRVADYDGYNQFVVHRSPEPLMSPSWSADGSKLAYVTFESGRSALVVQTLANGDIKQVASFPRHNGAPAFSPDGSKLAFALSKSGSLNLYVMNLGSGQISQVTDGRSNNTEPTWFPDSQTLAYTSDQAGRPQIYKIGINGGAPQRLTWEGSQNQDSEISSDGKFLVMVSSNSGAQHIAKQDLVTGGVQVLTDTFLDETPSIAPNGTMVIYSSKQGLGSVLQLVSTDGRFKARLPATDGQVRFPAWSPYM
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PHSC_SALTY
Sequence: MNTIWGAELHYAPDYWPLWLIYAGVVVLLMLVGLVIHALLRRMLAPKTAGGEEHRDYLYSLAIRRWHWGNALLFVLLLLSGLFGHFSLGPVALMVQVHTWCGFALLAFWVGFVLINLTTGNGRHYRVNFSGLVTRCIRQTRFYLFGIMKGEAHPFVATEQNKFNPLQQLAYLAIMYALVPLLIITGLLCLYPQVAGLGPVMLVLHMALAIIGLLFICAHLYLCTLGDTPGQIFRSMVDGYHRHRTAPRGDKSAV
What is the function of this protein?
Component of the PhsABC thiosulfate reductase that catalyzes the reduction of thiosulfate to sulfite and hydrogen sulfide, with menaquinol as the sole electron donor.  Proton motive force (PMF) is required to drive transmembrane electron transfer within the reductase.  The PhsC subunit anchors the complex to the membrane and contains the site for menaquinol oxidation.
What are the official names of this protein?
Thiosulfate reductase cytochrome B subunit PhsC, Thiosulfate reductase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the PhsC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPD_GEOSL
Sequence: MISNAIARRYAKALVQLGAEEGAVDRFGVELGQFTALLDGNADLASVLKSPAYRIEAKREILRDVLAKLNLSGTVSNFLQVLLDRGRIGFTPQIAHSYAVFADELSGIVRPVLTSAFPLDDAQVEGMKSALAKATGKRVELSAQVDSALIGGVVTKIGDKVFDGSVRTQLNRIQDILQKG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LPT_SALCH
Sequence: MNRISTTTITTITITTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: SYI_NAUPA
Sequence: MDYKDTLLLPKTTFPMRGNLPQNEPKKYKKWFSEHVYERMKQNRVGNDKFNLHDGPPYANGHIHIGHALNKILKDMIVKYYYFQGFDVRYTPGWDCHGLPIEQQVEKKIGREKKESLPKSKVRELCRQHAAKFIEIQKEEFQNLGVIGDWDNPYKTMDFEFEANIYKALAEIAKKGLLVERSKPVFWCMHDKTALAEAEVEYEDKEDYSIYVAFPLSNEAKSKLGIDNASIVIWTTTPWTLPANMGIALNPEEKYVLSEDGKIVAKELYENLKEAEVVSGEIVKEFDASELENLKAINPLNGRESVIILGEHVTMDGGTGCVHTAPGHGEEDYRVWLKYGFSEILQPVDDEGKYSNLIVTEKLLPEEFKGMHIFEANPKILDLLGDNLVKVSKFTHSYPHCWRCHNPVIFRATKQFFIAMDKEVNGDTLRHRALSEIEKVEFTPKTGKNRLSTMVANRPDWCISRQRDWGVPIAFFRNKDTGELIIDDEIIENVYEIFKVKGADAWYDLSIEELLPESKKEMASKLEKVNDILDVWFDSGSTWFAVLKNGPYDAGEYPANMYLEGSDQHRGWFQSSLLVSTSIEERAPYKSILTHGFTVDEKGEKMSKSKGNVVAPQEVSKKFGTEILRLWVATSDYSGDIKISDGILKQVAEQYRKIRNTIRFLLANVNDLEEIKLTNPSMIDRWILARSKEVFDEVVALFGKYDFSKAFNILNNFIVTELSAIYMDVCKDRLYCEPLNSEKRRNSQSTMAVIVKELISLLAPVLTYTMDEAVEHAPKVIKEDAKDVFDFVYTPLTAVENPIDEEILEIRRRFFEIVDRLKKEKVIKDTLELAIETNYDKLLVDEMADFFVVSLISDNIEGETLDEFHISDEQFVVKIKRSPLHKCPRCWRYLAEEEGALCERCEKAING
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_BURVG
Sequence: MSLMTKLGFRALVASCLIAAGGAANAQVNVLITGVGSTQFPIATANFANEAGLPQQVTSIVRADLARSGKFTNIDAGSTPVPETASVDLGAWKAKGANAFVAGSVNREANGQYKVNFILYDTVKQQSLGGLSLTANDTTLRTAGHKIADYIYQKLLGVRGVFATRLSYVIKTGNRYQLQISDSDGQNARIALSSTEPIISPAWSPSGTKVAYVSFERKKPIVYIHDLPTGRRYMVSDQKGNNSAPAWSPDGNTLAVALSLTGNTQIYTVNANGGGLRRLTQSSSIDTEPFYSPDGHWIYFTSDRGGAPQIYRMPAQGESAGAAQRVTFTGSYNTSPRVSPDGKLLAYISRTGGGFKLYVQDLQTGAANAITNTNRDESPSFAANGQYILYATQSGGRNVLAAVPTDGSAPPQILSVQGGSVREPSWGPFMQ
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LUXS_LACCB
Sequence: MAKVESFTLDHTAVKAPYVRLITTEHGAKGDVISNYDLRLVQPNTAAIDTAGLHTIEHLLASLLRDRMDGVIDCSPFGCRTGFHLITWGEHSTTEVAKALKSSLEAIANDITWDDVPGVDIKSCGNYKDHSLFSAKEWAKLILSRGISNDPYTRQVV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: LIN14_CAEBR
Sequence: MGKGQPIEPNIEQSLVDLCKRTVAMNLLHCYPTTTEHELSCEEWGNGTERSQSMAACQGCVELRKEVHDLRTAVNLILPMLPLYPQLPNTFTTAANIAAQPALHQVLQQSLLRRKPTAHTPTVPQPECPGQLRTVLSSPGSALPNVMLMNHLMINGLKPVSPTLPNGHIQPAVGEASMQTDEQQVKWSSPSSVDSNGQKTDSSAASAGDNQNIDVIGDGSESPTSSNHSVQELAMLTSHQNLFNAFKDSQFIFNQVPKQEPVAPLRVAPATNGTTNGATKAAGPERKPRKPVNDDIVKIVRNQDLSEENIATFQIPVPKAHLSDPTFRPVSEQQIIQQIIQGKKYDEMEVGETMIQLCKKLAEKRVFGPRLMSQTTVAGLNHSNYSNLPIKGICYIQHVCRKVLYDKFENEEDFWDKFREAMRKLAARCRRVRHAKKTKHNREEAQAEMLSKRYGEDIPFNLNGSGLIIPKSEPSETPAVNGDINMITMGQIGTLLTQFNADRKTPLTEVLPAELLTTFLSYLNRPKQEVQSPPPAQNPQNPN
What is the function of this protein?
Heterochronic protein which controls the choice of stage specific cell fates.  Involved in the temporal progression of vulval fate patterning, possibly by inhibiting lin-12.  Acts as a transcription factor involved in the stage-specific repression of insulin/insulin-like growth factor gene ins-33.
What are the official names of this protein?
Protein lin-14, Abnormal cell lineage protein 14.
What are the subcellular locations of this protein?
Nucleus. Note=May associate with mitotic chromosomes.
Protein: GT15_ORYSJ
Sequence: MRRWVLAIAILAAAVCFFLGAQAQEVRQGHQTERISGSAGDVLEDDPVGRLKVYVYDLPSKYNKKLLKKDPRCLNHMFAAEIFMHRFLLSSAVRTFNPEEADWFYTPVYTTCDLTPSGLPLPFKSPRMMRSAIELIATNWPYWNRSEGADHFFVTPHDFGACFHYQEEKAIGRGILPLLQRATLVQTFGQKNHVCLKDGSITIPPYAPPQKMQAHLIPPDTPRSIFVYFRGLFYDTSNDPEGGYYARGARASVWENFKNNPLFDISTDHPPTYYEDMQRSVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVAEEDVPKLDSILTSIPTDVILRKQRLLANPSMKQAMLFPQPAQAGDAFHQILNGLARKLPHGENVFLKPGERALNWTAGPVGDLKPW
What is the function of this protein?
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
What are the official names of this protein?
Probable glucuronosyltransferase Os01g0926700.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: CBIM_THEVB
Sequence: MVKPTQAKRYASLGAIALLTTSLVVASPNPALAMHISEGFLPLGWAVGWWLAFLPFLAWGLWSLQQQIKQHSESVLLVALAGAYAFVVSSLKIPSVTGSCSHPIGIALGAILFRPPLMAVLGTLVLLFQSLLIAHGGLTTLGANAFSMAVVGPWLAWLTYCGVSRLRVKPAIALFAASFISNVGTYTLTSLQLALAFPDSVGGLATSFAKFGTLFAVTQIPLAISEGLLTVLVWNWLTTYCVAELQALRLLPQEELP
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiM, Energy-coupling factor transporter probable substrate-capture protein CbiM, ECF transporter S component CbiM.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDK6_HUMAN
Sequence: MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSELNTA
What is the function of this protein?
Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition.  Phosphorylates pRB/RB1 and NPM1.  Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle.  Involved in initiation and maintenance of cell cycle exit during cell differentiation; prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types (e. g.  erythroid and hematopoietic cells).  Essential for cell proliferation within the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles.  Required during thymocyte development.  Promotes the production of newborn neurons, probably by modulating G1 length.  Promotes, at least in astrocytes, changes in patterns of gene expression, changes in the actin cytoskeleton including loss of stress fibers, and enhanced motility during cell differentiation.  Prevents myeloid differentiation by interfering with RUNX1 and reducing its transcription transactivation activity, but promotes proliferation of normal myeloid progenitors.  Delays senescence.  Promotes the proliferation of beta-cells in pancreatic islets of Langerhans.  May play a role in the centrosome organization during the cell cycle phases (PubMed:23918663).
What are the official names of this protein?
Cyclin-dependent kinase 6, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, ruffle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized to the ruffling edge of spreading fibroblasts. Kinase activity only in nucleus. Localized to the cytosol of neurons and showed prominent staining around either side of the nucleus (By similarity). Present in the cytosol and in the nucleus in interphase cells and at the centrosome during mitosis from prophase to telophase (PubMed:23918663).
Protein: TBX2_CAEEL
Sequence: MAFNPFALGRPDLLLPFMGAGVGGPGAGGPPPNLFFSMLQAGFPPGPVGSPPEDDGVTDDPKVELDERELWQQFSQCGTEMVITKSGRRIFPAYRVKISGLDKKSQYFVMMDLVPADEHRYKFNNSRWMIAGKADPEMPKTLYIHPDSPSTGEHWMSKGANFHKLKLTNNISDKHGYTILNSMHKYQPRLHVVRCADRHNLMYSTFRTFVFRETEFIAVTAYQNEKVTELKIENNPFAKGFRDAGAGKREKKRQLHRMNGDATQSPPGKTASLPTHSPHPSESNSEDDEPTLKKCKPEPSQTPTTSSLSTSTTPTLSAHHPLRSPQFCIPPPIDMMYQNMPMDLLAHWQMATLFPQFSMALNSPAAAASLLSKHLAKASSECKVEATSEDSEEAEKPEVKKEQKSVTPPKKGGFDVLDLLSKP
What is the function of this protein?
Involved in the transcriptional regulation of genes required for the development of pharyngeal muscles derived from the ABa lineage (PubMed:16701625, PubMed:23933492).  Acts as a transcriptional repressor and binds to T-box binding sites in its own promoter to negatively autoregulate its own expression in neurons, seam cells and the gut in order to restrict its expression to certain tissues (PubMed:25873636).  May function together with the nfya-1-NF-Y complex to repress its own expression (PubMed:25873636).  Plays a role in neural fate specification in the hermaphrodite-specific neuron (HSN)/PHB neuron lineage, acting in concert with homeobox protein egl-5 and the asymmetric cell division protein ham-1.
What are the official names of this protein?
T-box protein 2.
What are the subcellular locations of this protein?
Nucleus.