PharMolix/UniProtQA huggingface dataset:
Protein: RECR_CLOK5
Sequence: MDFYPVAIEKLIEEFAKLPGIGRKTAQRLTLHVLNLPADEVREFAKALVKARGTIKYCSICGNFTDSDPCAICSNPNRDKSIICVIEEPKDIMSMERIKEYNGVYHVLHGNISPMAGRGPEDIKLRELIRRINGDVNEVIVATNPNVEGEATAMYISKILKHLGVKVTRIAHGIPVGGNLEYADEVTLLKALEGRTEI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: S26A2_HORSE
Sequence: MSSESKEPHVLSPKDSFEGNDRYSPPSRIHLELEKKSSTDFKQFEASEPCRPYPRIHMEPQEKSNTNFKQFVIKKLQKSCQCSPTKAKNMIFGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASLIYFLLGTSRHISVGIFGVLCLMIGEVVDRELLKAGYDTVHIAPSLGMVSNGSTSLNQTSDRICDRSCYAIKVGSTVTFLAGIYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLSLPRSSGVGSLITTWIHIFRNIHKTNVCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPTELVVVVAATLASHFGKLHEKYNTSIAGHIPTGFMPPKAPDWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCQSQLSGVMTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWRVSRMDTVIWFVTMLSSALISTELGLLIGVCFSMFCVILRTQKPKVSLLGLVEETEIFESMSAYKNLQARPGIKIFRFVAPLYYINKECFKSALYKKTLNPVLVKAAQKKAAKRKIKKQPVTLSGIQNEISVQLSHDPLELRTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPSVRDSLARGEYCKDEEENLLFYSVYEAMAFAEESQNQKGICIPNGL
What is the function of this protein?
Sulfate transporter.  May play a role in endochondral bone formation.
What are the official names of this protein?
Sulfate transporter, Solute carrier family 26 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_CLOBJ
Sequence: MAAGMKGKRSRRRKERKNVEHGCAHIKSTFNNSIVTITDSVGNTLSWASAGGLGFRGSRKSTPFAAQMAAETAAKVAMEHGLKSIEVYVKGPGSGREAAIRSLQAAGLEVTLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MFD_STAAR
Sequence: MTILTTLIKEDNHFQDLNQVFGQANTLVTGLSPSAKVTMIAEKYAQSNQQLLLITNNLYQADKLETDLLQFVDVEELYKYPVQDIMTEEFSTQSPQLMSERIRTLTALAQGKKGLFIVPLNGLKKWLTPVEMWQNHQMTLRVGEDIDVDQFLNKLVNMGYKRESVVSHIGEFSLRGGIIDIFPLIGEPIRIELFDTEIDSIRDFDVETQRSKDNIEEVDITTASDYIITEEVISHLKEELKTAYENTRPKIDKSVRNDLKETYESFKLFESTYFDHQILRRLVAFMYETPSTIIDYFQKDAIIAVDEFNRIKETEESLTVESDSFISNVIESGNGFIGQSFIKYDDFETLIEGYPVTYFSLFATTMPIKLNHIIKFSCKPVQQFYGQYDIMRSEFQRYVNQNYHIVVLVETETKVERMQAMLSEMHIPSITKLHRSMSSGQAVIIEGSLSEGFELPDMGLVVITERELFKSKQKKQRKRTKAISNAEKIKSYQDLNVGDYIVHVHHGVGRYLGVETLEVGQIHRDYIKLQYKGTDQLFVPVDQMDQVQKYVASEDKTPKLNKLGGSEWKKTKAKVQQSVEDIAEELIDLYKEREMAEGYQYGEDTAEQTTFELDFPYELTPDQAKSIDEIKDDMQKSRPMDRLLCGDVGYGKTEVAVRAAFKAVMEGKQVAFLVPTTILAQQHYETLIERMQDFPVEIQLMSRFRTPKEIKQTKEGLKTGFVDIVVGTHKLLSKDIQYKDLGLLIVDEEQRFGVRHKERIKTLKHNVDVLTLTATPIPRTLHMSMLGVRDLSVIETPPENRFPVQTYVLEQNMSFIKEALERELSRDGQVFYLYNKVQSIYEKREQLQMLMPDANIAVAHGQMTERDLEETMLSFINNEYDILVTTTIIETGVDVPNANTLIIEDADRFGLSQLYQLRGRVGRSSRIGYAYFLHPANKVLTETAEDRLQAIKEFTELGSGFKIAMRDLNIRGAGNLLGKQQHGFIDTVGFDLYSQMLEEAVNEKRGIKEPESEVPEVEVDLNLDAYLPTEYIANEQAKIEIYKKLRKTETFDQIIDIKDELIDRFNDYPVEVARLLDIVEIKVHALHSGITLIKDKGKIIDIHLSVKATENIDGEVLFKATQPLGRTMKVGVQNNAMTITLTKQNQWLDSLKFLVKCIEESMRISDEA
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_RHOCS
Sequence: MAKLGKRLKKAVSTVDRDKFYALDEAVKTVRSNATAKFDETVEIAMNLGIDPRHADQMVRGMVQLPNGTGKTVRVAVFARAGKADEALAAGADIVGAEDLADKIQAGEFNFDRCIATPDMMGVVGRLGKILGPRGLMPNPKLGTVTPNVAEAVKAAKGGAVEFRAEKTGIVHAGVGKASFSEQALEENIRAFVSAINRAKPSGAKGTYIEKVSLSSTMGPGIKLDIPALVASLGG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: EUTC_PSEPG
Sequence: MDHRTPTPDNPWLALRNLTPARIALGRTGTSLPTGAQLDFQFAHAQARDAVHLAFDHAGLASQLSDRGRDSLVLHSAASDRHQYLQRPDLGRRLNEDSIATLRQHTQANPGGVDLAIVVADGLSALAVHRHTLPFLNRFEEQAAADGWTSAPVVLVQQGRVAVADEVGELLGARMTVMLIGERPGLSSPDSLGLYFTYAPKVGLTDAYRNCISNIRLEGLSYGMAAHRLLYLMREACRRQLSGVNLKDEAEVHSLESEGSASQKGNFLLGKG
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: MCA1A_ASPFC
Sequence: MQNHHHQQSSYGGGYPGQAYREQHPPPNPYGYGQPSPQPGYGAPPPHNGYGQPPSGYGQPPPPTGNAVYGGRQPGMNQYQNTYSHGHQGGPPPPPTDPVAFGHGAPQGYSFQYSRCTGKRKALLIGINYFGQKGQLRGCINDVKNMSTYLNQNFGYAREDMVLLTDDQQNPMSQPTKANILRAMHWLVKDAQPNDSLFFHYSGHGGQTPDLDGDEEDGYDEVIYPVDFRQAGHIVDDEMHRIMVRPLRPGVRLTAIFDSCHSGSALDLPYIYSTQGILKEPNLAKEAGQGLLGVVSAYARGDMSGMVSTAVGFLKRATKGDEAYTRSKQTKTSPADVIMWSGSKDSQTSQDAQIGGQATGAMSWAFITALRKNPQQSYVQLLNSIRDELATKYSQKPQLSCSHPLDTNLLYVM
What is the function of this protein?
Involved in cell death (apoptosis) (By similarity).  Required for the apoptotic-like loss of membrane phospholipid asymmetry at stationary phase and facilitates growth under conditions of endoplasmic reticulum stress.
What are the official names of this protein?
Metacaspase-1A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: NDHI_TRIBB
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETHIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ACSA_METEP
Sequence: MSEKVIDVQDAWRDRALIDEAKYKEMYEASVSGPETFWGEHGKRIDWSTPFSKVKNTSFAPGDVSIKWFEDGKTNVALNCIDRHLATRGDQTAIIWEGDDPNESKHITYRQLHAEVCRMANVLRNRGVGKGDRVTLYLPMIPEAAYAMLACARLGAIHAIVFGGFSPDSLASRIKGCGSKLVITADEGLRGGRKVPLKANVDEAIKRLDKDLVDHVIVVKRTGGNVAMEPGRDVYYHEAAEQVTDECPAEAVEAEHPLFILYTSGSTGQPKGVVHTTGGYLVYASMTHQYVFDYHDGDVYWCTADVGWVTGHSYIVYGPLANGATTLMFEGIPTYPSNSRFWEVIDKHNVNIFYTAPTAIRSLMGGGEGPVKKTSRQSLRVLGSVGEPINPEAWDWYYRVVGDSRCPIVDTWWQTETGGILITPLPGATRLKPGSATLPFFGVQPVMVDAEGKILDGACEGNLCIKDSWPGQMRTVYGDHERFEQTYFSTYKDLYFTGDGARRDADGYYWITGRVDDVINVSGHRMGTAEVESSLVAHPKVSEAAVVGYPHNVKGQGIYAYVTLNEGEEGTDELRKELVTWVRKDIGPIASPDLLQFAPGLPKTRSGKIMRRILRKIAEDDFGSLGDTSTLAEPAVVDDLIENRQNRSA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ITA2B_MOUSE
Sequence: MARASCAWHSLWLLQWTPLFLGPSAVPPVWALNLDSEKFSVYAGPNGSHFGFSVDFHKDKHGSVSIVVGAPRALNASQEETGAVFLCPWKANGGKCNPLLFDLRDETRNLGFQIFQTFKTGQGLGASVVSWNDVIVACAPWQHWNVLEKRDEAEKTPVGGCFLAQLQSGGRAEYSPCRANTMSSVYAESFRGDKRYCEAGFSLAVTQAGELVLGAPGGYFFLGLLARVPIENIISSYRPGTLLWHVSNQRFTYDNSNPVFFDGYRGYSVAVGEFDGDPSTTEYVSGAPTWSWTLGAVEILDSYYQPLHRLHGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPKGPQALSTPTLLLTGTQLYGRFGSAIAPLGDLNRDGYNDIAVAAPYGGPSGQGQVLIFLGQSEGLSPRPSQVLDSPFPTGSGFGFSLRGAVDIDDNGYPDLIVGAYGASKVAVYRAQPVVMATVQLMVQDSLNPTLKNCVLDQTKTPVSCFNIQMCVGATGHNIPQKLHLKAELQLDLQKPRQGRRVLLLASQQASLTLSLDLGGRDKPICHTTGAFLRDEADFRDKLSPIVLSLNVSLPPEETGGAPAVVLHGETHVQEQTRIILDCGEDDLCVPQLRLTATAGDSPLLIGADNVLELKIEAANDGEGAYEAELAVHLPPGAHYMRALSNIEGFERLVCTQKKENESRVALCELGNPMKKDTRIGITMLVSVENLEEAGESVSFQLQVRSKNSQNPNSKVVMLPVAIQAEATVELRGNSFPASLVVAAEEGDREQEDLDRWVSRLEHTYELHNIGPGTVNGLRLLIHIPGQSQPSDLLYILDVQPQGGLLCSTQPSPKVDWKLSTPSPSSIRPVHHQRERRQAFLQGPKPGQQDPVLVSCDGSASCTVVECELREMVRGQRAMVTVQVMLGLSSLRQRPQEQFVLQSHAWFNVSSLPYSVPVVSLPSGQARVQTQLLRALEERAIPVWWVLVGVLGGLLLLTLLVLAMWKAGFFKRNRPPLEEDEEEE
What is the function of this protein?
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin.  It recognizes the sequence R-G-D in a wide array of ligands.  It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain.  Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen.  This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
What are the official names of this protein?
Integrin alpha-IIb, GPalpha IIb, GPIIb, Platelet membrane glycoprotein IIb.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: REX_STRPJ
Sequence: MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD_HAEI8
Sequence: MAEEPIRLTQYSHGAGUGCKISPKVLGTILHSELEKFYDPNLLVGNETADDAAVYDLGNGTAIISTTDFFMPIVDDPFDFGRIAATNAISDIFAMGGKPIMGIAILGFPTNVLPAEVAQKIVDGGRFACHQAGIALAGGHSIDSPEPIFGLAVTGVIDTEKVKRNASAKSGCKLYMTKPLGIGILTTAEKKGKLKPEHQGLATAAMCQMNSIGSQFSQVDGVTAMTDVTGFGLLGHLIEICEGSNLSAVVFSDKIKTLDGVKDYIAQGCVPGGTGRNFESYGHKVGALTEEQKAILCDPQTSGGLLVAVEPNSVQTIIEIAKDTGIDLYEVGKLKPKSESDIVVEVK
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: RL5_STRP1
Sequence: MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDAVSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTTANTDEESRELLKGLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DEF2_VIBVY
Sequence: MLLGCCHLGYKMSRIEPTRFVLFRHSSTFRVHMSVLQVLTFPDDRLRTVAKPVEKVTPEIQKIVDDMIETMYDEEGIGLAATQVDIHQRIVVIDISESRNEPMVLINPEILEKRGEDGIEEGCLSVPGARALVPRAAEVTVKALDRDGHEFTLEADDLLAICIQHELDHLQGKLFVDYLSPLKRKRIQDKLAKIKRFNEKQR
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 2, PDF 2, Polypeptide deformylase 2.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: LSPA_METNO
Sequence: MRPLPFGLLVAAATLVLDQATKLGLLFLTDLPIRQPIVLAPFAQLVVVWNRGVSYGLFQQHTELGRWLLVAVSVLAAVALTAWMARTGTRLLAGALGLIVGGAIGNAIDRIAYGAVFDFVHLHAGGWSWYVFNVADAGIVLGVAGLLYDAVRAERRNAREIRSDA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1735_MYCTO
Sequence: MFLYVAVGSLVVARLLLYPLRPADLTPPYWVAMGATAITVLAGAHIVEMADAPMAIVTSGLVAGASVVFWAFGPWLIPPLVAASIWKHVVHRVPLRYEATLWSVVFPLGMYGVGAYRLGLAAHLPIVESIGEFEGWVALAVWTITFVAMLHHLAATIGRSGRSSHAIGAADDTHAIICRPPRSFDHQVRAFRRNQPM
What are the official names of this protein?
Uncharacterized membrane protein MT1776.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DICC_ECOLI
Sequence: MLKTDALLYFGSKTKLAQAAGIRLASLYSWKGDLVPEGRAMRLQEASGGELQYDPKVYDEYRKTKRAGRLNNENHS
What is the function of this protein?
This protein is a repressor of division inhibition gene dicB.
What are the official names of this protein?
Repressor protein of division inhibition gene dicB.
Protein: VIAA_SHIFL
Sequence: MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKAAITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRLNSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQFIVKYGEFLNEQPELKRLAEQLGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELAKLGITELEYEFYRRLVEKQLLTYRLHGESWREKVFERPVVHKDYDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGGTDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVAMSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: GSA_ACIBC
Sequence: MSLSPKQEQLFKQASKHIPGGVNSPVRAFNGVGGTPVFIEKAKGAYLWDVDGKRYVDYVGSWGPMILGHAHPDIIKAVQTAAEDGLSFGAPTVHETTLADIICEIMPSIELVRMTNSGTEATMTAIRLARGYTGRDKIVKFEGCYHGHSDSLLVKAGSGLLTKGEGEPTSKGVPADFAKHTLTLPYNDVAALKECFAKFGHEIAGVIIEPVAGNMNMVKPIDGFLQAIRDVCDEYKSVFIIDEVMTGFRVALGGAQSVYNVKPDLTTLGKIIGAGLPVGAFGGKREIMECIAPLGGVYQAGTLSGNPLAMRAGIEMFKHLRQPDFYSKLSAQLEKLLAGLQAAADEAGIPFKTQQAGAMFGLYFTDQEDITSFDSMLACDIEAFKKFFHGMLKRGVNLAPSAFEAGFISSAHSDEDIEFTIQAAKETFAEMK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_MARMS
Sequence: MSEKAVVVYSGGMDSFTVLNTAIQNGLDVYALSFNYGQKHSKELEVAAHVCRKLGISHKVVDITAINSLMANSSLTGDAEIPEGHYEDDNMKSTVVPNRNMVLLSMAIAYAVSLEAGKVYYGAHSGDHHIYPDCRPEFVEAMNAVSKIANYQSVEIVTPFLHSSKGEILKAGLDMNLNYANTWTCYNGREKSCGKCGACYERLEAFAEQGKTDPLEYEA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: YQD7_CAEEL
Sequence: MSYYEPYSSRQRMLPNTPDNYDDASDHPQFASRSGSSSLQSSLSKRANSTRRSLKELSEGVQQRFQPITHGRSLQRITEDDSPSTPTAPPRPNRQLYRNSIDHLSMSEGALKQQTSEESPSEVSEGQRSNWSQSVVKIENALHRNYYTIAYSIVIIAYFAGFAEYLYFRLTSLIVPEHLVFHPPCEGKATRKIGKDGFHYGISICAFIGVATFQLMCFFGLTISEKWTQSKENPRESRRAAQREEFALFVRTMISSTMYRVFLCYGICSLINCAIIFYMVGIQDSLGDVVSTIFLYVFDAVVILYFIAFPLTTVIYHPYVHCFRRRGAPARFTLPDVGQRTQTSTLESNISGLEEAMGKATGGTPPVHRNPSPPVIPSLNFSRQDPLRQGHRSTGSISTDIPVLEEYLHSPRRQLPQPRLAVEENLDDERITTFV
What are the official names of this protein?
Uncharacterized protein C32D5.7.
Protein: SPEM1_HUMAN
Sequence: MAMVERPRPEWASYHNCNSNSCQDLGNSVLLLLGLIICINISINIVTLLWSRFRGVLYQVFHDTICEKEAPKSSLLRKQTQPPKKQSSPAVHLRCTMDPVMMTVSPPPAHRHRRRGSPTRCAHCPVAWAPDTDDEKPHQYPAICSYHWDVPEDWEGFQHTQGTWVPWSQDAPESPPQTIRFQPTVEERPLKTGIWSELGLRAYVYPVNPPPPSPEAPSHKNGGEGAVPEAEAAQYQPVPAPTLGPAVIPEFSRHRSSGRIVYDARDMRRRLRELTREVEALSGCYPLASGSSTAEETSKNWVYRSLTGR
What is the function of this protein?
Required for proper cytoplasm removal during spermatogenesis.
What are the official names of this protein?
Spermatid maturation protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Cytoplasm.
Protein: VP2_POVBO
Sequence: MGALLTILAEVFELATATGLSAEAILTGEAFTTAELLQAHIANLVEVGELSVAEALAATEVTSEAFEALQSISSVLPTAFIGVAATEGAILGSLITLTATSSALYPSTWKHSTPSANLNQEMALVPYIGDLDIFFPGAETISRFVYSIDPFRWASYLYNIVGRAVWEHLFRETRRQIAYHTTDIAGRTAQSIHHTIANFLENVRWTVSHLGTNLYSGLHNYYRQLPPLNPPQSRELARRLGVPQPDRQIFEKGEEGMKHPVSAEYVEKYGAPGGAEQRVAPDWLLPLLLGLYGDLTPAWEAEVEEEENEQDEEEYEPPQKRIKRTAKSSSKVNNKRGDRSARSPYRTRQHNHN
What is the function of this protein?
Structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers.  Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane.  Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2 or VP3 nuclear localization signal (shared C-terminus).  Plays a role in virion assembly within the nucleus (By similarity).
What are the official names of this protein?
Minor capsid protein VP2, Minor structural protein VP2.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses capsid protein VP2 family.
What are the subcellular locations of this protein?
[Isoform VP2]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane. SUBCELLULAR LOCATION: [Isoform VP3]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane.
Protein: IOVO_ANTVI
Sequence: TATVDCSDYPKPACTLEYMPFCGSDSKTYSNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: PRS6A_DICDI
Sequence: MSNKRTTTKDESLPQAEKEAVIPDEIFQMTADEVNRKAKLLENETKVLRSEHISKHLEMDSIQKRIKENNDKLQVNTQLPHLVANVVEIIDMVLDGETQPSKCVVVKASTRQTIFLAYPGIVDVDKLRPGDLVGINKDSYIILDTLPPEYDSRVKAMEIDEKPTEEYSDIGGLDKQIQELVEAVVLPMTHKERFESIGIKPPKGVLMYGPPGTGKTLLARACAAQTNSTYLKLAGPQLVQMFIGDGAKLVRDAFALAKEKGPTIIFIDELDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDANIKVIAATNRIDILDPALLRSGRLDRKIEFPLPNEEARAHILQIHSRKMNVSADVNFDELARSSEDFNGAQLKAVCVEAGMIALRRGGTELIHNDFVEGCVEVMAKKKKTLEYYA
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit 6A homolog, 26S proteasome AAA-ATPase subunit RPT5, Proteasome 26S subunit ATPase 3.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MIAB_BACHK
Sequence: MNEQQRLASQQVNSSTKKEEKDYSKYFESVYQPPSLKEAKKRGKEEVKIERDFGLPEEFRNFGTGRKFYIRTYGCQMNEHDTEVMAGIFTALGYEPTFSTEDADVVLLNTCAIRENAENKVFGELGHLKALKRRNPDLLIGVCGCMSQEESVVNKIMQKNQHVDMVFGTHNIHRLPYILKDAMFSKETVVEVWSKEGDVIENLPKVRRGDIKAWVNIMYGCDKFCTYCIVPYTRGKERSRRPEDIIQEIRHLAANGYKEITLLGQNVNAYGKDFEDIEYGLGDLMDELRKVDIARIRFTTSHPRDFDDHLIEVLGKGGNLVEHIHLPVQSGSTEMLKIMARKYSREHYLELVRKIKEAIPNAVLTTDIIVGFPNETDEQFEETMSLYREVGFDTAFTFIYSPREGTPAAKMKDNVPMEVKKERLQRLNALVNKLAIEKNDRYKGQIVEVLVDGESKNNPEVLAGYTRTNKLVNFVAPKSLIGQLVKVKVTDAKTWSLNGELVEEPIEVE
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBR1_MOUSE
Sequence: MSSSRPVALVTGANKGIGFAITRDLCRKFSGDVVLAARDEERGQTAVQKLQAEGLSPRFHQLDIDNPQSIRALRDFLLKEYGGLDVLVNNAGIAFKVNDDTPFHIQAEVTMKTNFFGTRDVCKELLPLIKPQGRVVNVSSMVSLRALKNCRLELQQKFRSETITEEELVGLMNKFVEDTKKGVHAEEGWPNSAYGVTKIGVTVLSRILARKLNEQRRGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVQDKKVEPW
What is the function of this protein?
NADPH-dependent reductase with broad substrate specificity.  Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics.  Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol (By similarity).  Can convert prostaglandin E to prostaglandin F2-alpha (By similarity).  Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates.  Catalyzes the reduction of S-nitrosoglutathione.  In addition, participates in the glucocorticoid metabolism by catalyzing the NADPH-dependent cortisol/corticosterone into 20beta-dihydrocortisol (20b-DHF) or 20beta-corticosterone (20b-DHB), which are weak agonists of NR3C1 and NR3C2 in adipose tissue (PubMed:28878267, PubMed:33785425).
What are the official names of this protein?
Carbonyl reductase [NADPH] 1, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], 20-beta-hydroxysteroid dehydrogenase, Alcohol dehydrogenase [NAD(P)+] CBR1, NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, PG-9-KR, Prostaglandin-E(2) 9-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.