PharMolix/UniProtQA huggingface dataset:
Protein: VM3_MICIK
Sequence: TNTPEQDRYLQVKKYLEYVVVDNNMYRNYGNAGPCVMSAEISFEPLQEFSSCDIQEPLSQDIVQPAVCGNYYVEVGGECDCGSPKPCRSACCNAATCKLQREHQCDSGECCEKKDDCDLPEICTGRSAKCSCVISQGDLGYGMVEPGTKCTDGMVCSNEQCVDVQTAAK
What is the function of this protein?
Snake venom zinc metalloproteinase that calcium-independently catalyzes the conversion of prothrombin (F2) to alpha-thrombin through the formation of a thrombin intermediate.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like mikarin, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYP_PHEZH
Sequence: MRLSRYFMPTLREAPSDAQIVSHQLMLRAGMIRQEAAGIYAWLPLGLKVLKKIEQVVREEMDRAGAIEVLMPTLQLADLWRESGRYDDYGEEMLRIKDRHERDLLYGPTAEEVITDIFRAYIKSYKDLPKNLYNIQWKFRDERRPRFGVMRGREFLMKDAYSFDIDEAAARRAYNRMFCAYLNVYARLGLKAIPVRADTGPIGGDLSHEFIILADTGESQVFAHRDLVEMGAPGPDIDWDGDLEPLVQQRTRLYAASDEMHDQARFETEAPEDKRMTARGIEVGHIFYFGEKYSRPMNAKVAGPDGAERFVHMGSYGVGVSRLVGAIIEASHDEAGIVWPDSVAPFGAAVVNLRPGEAAVDAVAEQAYGALQAAGKEPLLDDRDERPGAKFASLDLVGVPWQLIVGPKGVAEGVVEIKRRATGERQTLPLDAALKAITA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_GLOC7
Sequence: MIQQQTYLNVADNSGARKLMCLRVLGTGNCRYGGIGDEIIAVVKDAIPNMPVKKSDVVKAVIVRTRHPLRRASGMTIRFDDNAAVIINNDGNPKGTRVFGPVARELRDKNYTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PYRH_ECOLI
Sequence: MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP, with ATP as the most efficient phosphate donor.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Is predominantly localized near the bacterial membranes.
Protein: GRN_HUMAN
Sequence: MWTLVSWVALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPALRQLL
What is the function of this protein?
Stabilizes CTSD through interaction with CTSD leading to maintain its aspartic-type peptidase activity.
What are the official names of this protein?
Progranulin, PGRN, Acrogranin, Epithelin precursor, Glycoprotein of 88 Kda, GP88, Glycoprotein 88, Granulin precursor, PC cell-derived growth factor, PCDGF, Proepithelin, PEPI.
What is the protein family that this protein belongs to?
Belongs to the granulin family.
What are the subcellular locations of this protein?
Secreted. Lysosome. Note=Endocytosed by SORT1 and delivred to lysosomes (PubMed:21092856, PubMed:28073925). Targeted to lysosome by PSAP via M6PR and LRP1, in both biosynthetic and endocytic pathways (PubMed:26370502, PubMed:28073925). Co-localized with GBA in the intracellular trafficking compartments until to lysosome (By similarity).
Protein: MUTS2_BACCN
Sequence: MLERTLRVLEYDKVKEQLLEHTASSLGRDKVKRLMPSTDFEEIVEMQDTTDEAAKVIRLKGHAPLGGIFDIRSNVKRAKIGSMLSPHELLDIASTMYGSRQMKRFIEDIVDNGAQLPILETHVAQIVSLYDLEKKITGCIGDGGEVLDSASDKLRGIRNQIRTAESRIREKLENMTRSSNAQKMLSDAIVTIRNDRYVIPVKQEYRGVYGGIVHDQSASGQTLFIEPQVIVELNNALQEARVKEKQEVERILMMLTEEVAAEADIVLANVEVIANLDFIFAKALYAKRMKATKPIVNNERYMELRQARHPLIDPKVIVPNDIVLGKDFTTIVITGPNTGGKTVTLKTVGICVLMAQSGLHIPVQEESEICVFKNIFADIGDEQSIEQSLSTFSSHMVNIVDILEKADFESLVLFDELGAGTDPQEGAALAISILDEVHNRGARVVATTHYPELKAYGYNRNQVINASVEFDVNTLSPTYKLLIGVPGRSNAFEISKRLGLSERVINRARNHISTDTNKIENMIAKLEESQKNAERDWKEAEELRKQSEKLHRELQRQIIEFNEERDERLLKAQKEGEEKVEAAKKEAEAIIRELRQLRKAQLANVKDHELIEAKSRLEGAAPELVKKQKVKVKNTAPKQQLRPGDEVKVLTFGQKGQLLKKVSDSEWNVQIGILKMKVKESDMEYINTPKQLEKKAVATVKGRDYHVSLELDLRGERFENAMMRVEKYLDDAQLANYPRVSIIHGKGTGALRQGVQDYLKNHRGVKSFRYGDMGEGGLGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: SYH_YERPG
Sequence: MAKNIQAIRGMNDYLPADTAIWQRIESILKQVLSGYGYSEIRMPIVEQTPLFKRAIGEVTDVVEKEMYTFDDRNGESLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRYERPQKGRYRQFHQLGAEVFGLPGPDIDAELILLTARWWRALGIFEHVKLELNSIGSLAARADYREALVAFLEQHVEVLDEDCKRRMYSNPLRVLDSKNPDVQQLLDDAPKLSDYLDEESKQHFAGLCELLDKASIPYTVNERLVRGLDYYNRTVFEWVTHSLGAQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNADFQVPATVDAYVISSGEGAQSAAMLLAESLRDALPTLKIMTNYGGGNVKKQFTRADKWGARVALMLGESEVAAQQVVVKDLRNGEQETLAQADVAARLALMLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_FERNB
Sequence: MEKINEYGSERIVSPERTGYDSYSLRPKFLSEYIGQENIKERLKLAIQASKMRGEQLDHILLAGPPGLGKTTLATIIANELNANIHVTSGPILEKQGDLAAILTNLEAGDVLFIDEIHRMNRNVEEILYSAMEDFQVDIMIGKGPAARSIRVELQPFTLIGATTRSGLLTSPLRNRFGMIFEMNFYTQEELKMIITRAAEVMGTLIDDDAALSIAKRSRGTPRIAIRLLKRVRDLSTVRGSENITLNIVEEVMRLLGVDEFGLDEMDRKILKTIIEIYKGGPVGLKSLAASLGITEDTISEVYEPFLVQSGFIARGARGRIATEKAYKYLGYNTLPGGLFDGFGNIE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: FKBP3_BOVIN
Sequence: MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQDHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFESKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSSKKKKNAKPLSFKVGIGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLIFEVELVDID
What is the function of this protein?
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two dinstinct cytoplasmic signal transmission pathways.  PPIases accelerate the folding of proteins.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP3, PPIase FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-25, FK506-binding protein 3, FKBP-3, Immunophilin FKBP25, Rapamycin-selective 25 kDa immunophilin, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 388R_IIV6
Sequence: MEKETTFLGLKLSEKGPGNDMVKKALGYSLKYLEIETFMDVIGFVKDPVMTDYFWHIMVDNHCRHLATVLLECLGYEGTYNKQQYAIKRFLKSNRINYSELSSDDPQIDLYPTIKEEMKNMKPNAIACRKWLIIEPREFKKVIMKLNTKNGDNIREYYIRLEELIKLYLEYSLYFKEREAQIEKQKSQFHIETLEKKLDEMKLEAEKRHDELLDKVEEVQYDLNVVGEKLDIAVEDRAPKVKAELLRERFVVLNRNDKRASCQYYVMRGQDHYINGKIFSYKNLHPNLKIIFDISCQPNPRNLFVRFKELKDNRFKVVGNNIQTLDEKALLEVFNKLNDDKRNIQLM
What are the official names of this protein?
Putative MSV199 domain-containing protein 388R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 006L/238R/313L/468L family.
Protein: GHT4_SCHPO
Sequence: MGRTLTSVLVVFISMAGWLGGADTGSISGILGMRDFQSRFADRYNPITNSYSYSAWRQALLTGTVNAGCLFGAMLSSPFTEAIGKKYSIAFFSGCYIIGQILLVTAVPSWVQIMVGKLFTGLTIGALSVLSPGYQSEVAPPQIRGAVVSTYQLFQTCGTLIAACINMGTHKLRKTASWRTSFGINILWGIFLMVGVLFLPESPRYLIYKGRDEEALRIMCQTAELDPESEIIQTNFNTIKSDIEMEMAGGKARWPEVFGKEVRYRTVLGFLTMLLRELIGNNYYFYYATQVFKGTGMTDIFLPAVILGAINFGTTFGALYTIDNLGRRNPLIFGAAFQSICFFIYAAVGDRKLIYKNGTSDHRAGAVMIVFSCLFLFSYCCSWGPMGWVIVGETFPIRYRSKCAAVATSGNWLGNFMVSFFTPFISNSIGFKLGYIYACINMTSAFQIFLMAKETKGLTLEEVNELYESDIKPWDSYKYVRQIESRRIHFSKEEEKREREKSKGYRGQEERFIENADGADNDDSSASSESFASAGAHSRSVFPRRSNVSEESHPTWV
What are the official names of this protein?
High-affinity hexose transporter ght4, Hexose transporter 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VSTX1_GRARO
Sequence: MKTSVFVLVLGLVLLFAVSFATEMEESARECGKFMWKCKNSNDCCKDLVCSSRWKWCVLASPF
What is the function of this protein?
Inhibits sodium channels Nav1. 7/SCN9A and potassium channels Kv11. 1/KCNH2.  Also binds the voltage-sensor domain of the potassium channel KvAP (from the archaeon Aeropyrum pernix) with very slow apparent binding kinetics and affects channel gating.  Reaches its target by dynamically partitioning into anionic or zwitterionic headgroup lipid membranes.  May bind to the open state of KvAP.
What are the official names of this protein?
Kappa-theraphotoxin-Gr3a, Kappa-TRTX-Gr3a, Voltage sensor toxin 1, VsTx1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 63 (VsTx1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAG_AERPE
Sequence: MKYLIRARLEVDGRVEKHDVIGAIFGQTESLLGSDFSLEELQNKDKLGRIHVELKYQGTKTIGSISVPSNLSRVETAIIAAMLETIDKIGPYPAKITIEEIRDLRLERLEKIKQRARELLRLMKEKEPDIREIIREVLQEEQAKAQVAKLVEYGPERLPAGPGVEKADTIIVVEGRSDVNTLLRYGYTNVIALGGAREKVPETIKRLAEQKKVILFVDGDRGGELILKNVLPQMKVDYVARAPEGREVESLTGREIAQALSQMKPAEIVARELGIEAAEKPAEEAVKREEEAAAEAKPPAPAVQEKAAKPPEEKPPTVKFTIPKAVLEAAKELRGTLEAIVYDKEWRELDRLKVRELYDYISKSEPGRIYAVVFDGIITQRLLDIASEKGVGIIIGNRIGNKITHKPTNVKFLTFSDLF
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: M1_I57A2
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVITTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRAIGTHPSSSAGLKSDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: MCAF1_HUMAN
Sequence: MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLENMDYIKDKEEVNGIEEICFDPEGSKAEWKETPCILSVNVKNKQDDDLNCEPLSPHNITPEPVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAPSGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLASGAPASTDPASDDLASGDLSSSELASDDLATGELASDELTSESTFDRTFEPKSVPVCEPVPEIDNIEPSSNKDDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETLETDDTTICSDRPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDNKSENILENTDSMETDEIIPILEKLAPSEDELTCFSKTSLLPIDETNPDLEEKMESSFGSPSKQESSESLPKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKPEEEEQVIHEDDERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQWLLEEKLCALQCAVFDKTLAELKTRVEKIECNKRHKTVLTELQAKIARLTKRFEAAKEDLKKRHEHPPNPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQTPVNTVSSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQVPSGNPQPTISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQPSGNVEFISVQSPPTVSGLTKNPVSLPSLPNPTKPNNVPSVPSPSIQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLPTVGPSGLYSPSTNRGPIQMKIPISAFSTSSAAEQNSNTTPRIENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEESGASQDPKKLNHTPVSTMSSSQPVSRPLQPIQPAPPLQPSGVPTSGPSQTTIHLLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTVMQAPAVRQVNPQNSVTVRVPQTTTYVVNNGLTLGSTGPQLTVHHRPPQVHTEPPRPVHPAPLPEAPQPQRLPPEAASTSLPQKPHLKLARVQSQNGIVLSWSVLEVDRSCATVDSYHLYAYHEEPSATVPSQWKKIGEVKALPLPMACTLTQFVSGSKYYFAVRAKDIYGRFGPFCDPQSTDVISSTQSS
What is the function of this protein?
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation.  Can both act as an activator or a repressor depending on the context.  Required for HUSH-mediated heterochromatin formation and gene silencing (PubMed:27732843).  Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1 (PubMed:12665582).  Stabilizes SETDB1, is required to stimulate histone methyltransferase activity of SETDB1 and facilitates the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3).  The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) (PubMed:14536086, PubMed:27732843).  Facilitates telomerase TERT and TERC gene expression by SP1 in cancer cells (PubMed:19106100).
What are the official names of this protein?
Activating transcription factor 7-interacting protein 1, ATF-interacting protein, ATF-IP, ATF7-interacting protein, ATFa-associated modulator, hAM, MBD1-containing chromatin-associated factor 1, P621.
What is the protein family that this protein belongs to?
Belongs to the MCAF family.
Protein: PBP2_NEIFL
Sequence: NIDGKGQEGLELSREDSLRGEDGAKVVLRDNKGNIVDSLDSPRNSVPKNGQDMILSLDQRIQTLAYDELNKAVAYHKAKAGAVVVLDAQTGEILALVNSPAYDPNQPGQANSEQRRNRAVTDMIEPGSAMKPFTIAKALDSGKVDPTDTFNTLPYKIGPATVQDTHVYPTLDVRGIMQKSSNVGTSKLSAMFTPKEMYDFYHDLGVGVRMHSGFPGETAGLLRSWRRWQKIEQATMSFGYGLQLSLLQLARAYTVLTHDGELLPVSFEKQAVAPKGKRVIKASTAKKVRELMVSVTEAGGTGIAGAVDGFDVGAKTGTARKLVNGRYVDNKHVGTFIGFAPAKNPRVIVAVTIDEPTANGYYGGVVAGPVFKEVMSGSLNILGVSPTKPLSNTATVKVPS
What is the function of this protein?
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
What are the official names of this protein?
Probable peptidoglycan D,D-transpeptidase PenA, Penicillin-binding protein 2, PBP-2.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family. FtsI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BIOA_HELPJ
Sequence: MNFQENLAALDLEYLWHPCSQMQEHQNFPIIPIKKAQGIYLYDFNDNAYMDLISSWWVNLFGHNNAYISQQLKNQIDNLEHVLLASFSHKPIITLSQRLCQLTGMDKCFYADNGSSCIEIALKMSYHAHFLKNQTRRKKLFLSLSNSYHGETLGALSVGDVKLYKDTYTPLLLKNLITPVPKNDSEIENSLNALKRLLDKHGEEICAFIAEPLLQCAGNMHIYSAKYLKQAVLWCKQKNIHIIFDEIATGFGRTGSMFAYEQCGIKPDFLCLSKGISGGYLPLSALLTHNEIYNQFYAPYEENKAFLHSHSYTGNALACACANATLDIFEKENVIEKNKALSEFIFSALQNALKPLIERQVVSDLRHLGMVFAFEVFLQTKERLSLAVFKKALKKGLLLRPLNNTIYLMPPYIITHEEIKKAIAGLVEAIDELKKAENK
What is the function of this protein?
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA).  It is the only aminotransferase known to utilize SAM as an amino donor.
What are the official names of this protein?
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, 7,8-diamino-pelargonic acid aminotransferase, DAPA AT, DAPA aminotransferase, 7,8-diaminononanoate synthase, DANS, Diaminopelargonic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RZOD_ECOLI
Sequence: MRKLKMMLCVMMLPLVVVGCTSKQSVSQCVKPPRPPAWIMQPPPDWQTPLNGIISPSERG
What is the function of this protein?
Component of the spanin complex that disrupts the outer membrane and causes cell lysis during virus exit.  The spanin complex conducts the final step in cell lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans (By similarity).
What are the official names of this protein?
Prophage outer membrane lipoprotein RzoD, o-spanin, Outer membrane lipoprotein Rz1 from lambdoid prophage DLP12, Spanin from lambdoid prophage DLP12, outer membrane subunit.
What is the protein family that this protein belongs to?
Belongs to the lambdalikevirus o-spanin family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: PUR9_CLOBK
Sequence: MIKRALISVFDKTGILDLAKFLESRDVEIISTGGTYKHLKENGVKVIDIEEVTGFPEMLDGRVKTLNPLIHGGILAIRDNEEHMKVIEEKGINPIDMVVVNLYPFFNKVEENLSFDEKVEFIDIGGPTMIRAAAKNFKDVVVLTDTKDYENVIDEIKENDQVNIKTRKKLAGKVFNLMSAYDAAISNFLLEEEYPEYLTLSYKKNMDLRYGENPHQTAAYYTSTVGKYPMKNFEKLNGKELSYNNIKDMDIAWKTVCEFEEVACCALKHNTPCGVAIGDTVQEVYTKAYECDPISIFGGIVAFNRKVDKETAENLAKIFLEIVVAPDFDEDALEVLKNKKNLRVIKCEEKSTEGKDMAKVDGGILVQKSDNKLLEDTKVVTEKSPTEQEMKDLIFGMKVVKYVKSNAIVVVKDGMAKGIGGGQVNRIWAAKEALDRAGDGIVLASDAFFPFGDVAEEAAKWGIKAIIQPGGSIRDEESIKVCDEKGISMVFTGIRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: MENH_SALNS
Sequence: MMLHAQHMPGQPGTPSLVFLHGFSGDCREWQPVGEQFHGCSRLYIDLPGHGGSAAIPVGGFADVIRLLRATLISYNILKFWLVGYSLGGRVAMMAACQGIPGLCGLVVEGGHPGLQNEQARAERRLSDGRWAERFRHEPLTEVFHDWYQQPVFASLTAQQRQALTALRSQNNGETLAAMLEATSLAAQPDLREALNALAFPFYYLCGERDSKFRALAQEVAATCHVIRNAGHNAHRENPAGVVDSLAQILRL
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: FAR9_KARBO
Sequence: GRGGASNYVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-9, FMRFa-9.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: VF224_IIV3
Sequence: MTLEWNIDDKFHLFFRKKRSVYIVGGVHHDEDEVDPKVVAQSGLQGDDGVVRLPPLNTLVNFLGHVSPYMHADYAFLHREWEYNRTASFADDLVNLPSVYDWRYVYPRDDEETKRKKRYIMPPDNQYLCGSCWAVSTASAIGDAYVVAGLVDWRPDISPAWALTCYPQGQCEGGSPALLLKEISQGNGIVSNHCLDYSFCASNPRCNGAAANHFGAENLSELVPKSCGCYVGDSMHYRYTVDPLIRTLAIGVGTVTEENIQSTIKRHILTHGPVLAGYFVLKNFTSGYFTRINGGVYFDRGNYIPGQALVFNDHYCSGDSYRGSHAVAIIGWGVARNVLYDTDKRGDVPYWYCRNSWRSTWGGDDGYFKMAMYPWNRVAQFEKLVTLRDRDNVPHRCGGIITFTVSTKPVKVKMNQLNTTLLPFPLLRDRSWYGGDQEEYRPAIVPKLAPSDGPNKPPLPLPVYYSALDLALLVLPALLIVIVVLIGKIPT
What is the function of this protein?
Probable cysteine protease.
What are the official names of this protein?
Probable cysteine proteinase 024R.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DCTA_RHOPA
Sequence: MSATTHIDAPALPKRGKSKPFYKVLYVQVLFAIVVGVLVGWLSPHFATNEWIKALGDGFVKLIKMVIAPIIFCTVVSGIAHIQDARKVGRVGIKALLYFEVVSSFALVLGLIVGNLFPVGHGLAAKPDAGAVAKYVDQASHMSAVDFVLHIIPDSVVGAFAKGDILQVLLFAVLFGFALMALGERGHRLRDVIDDAAHAVFGVIAIVMKAAPIGAFGAMAFTIGKYGPAALGNLIGLVALFYATSALFVVLVLGTIAKFVGFNIFKFIGYIKDELLIVLGTSSSESALPQLMEKLERLGCSKSVVGLVVPTGYSFNLDGTNIYMTLATLFIAQALGIELSFGDQVAILLVAMLTSKGASGVTGAGFVTLAGTLAAVNPALVPGMAIVFSIDKFMSEVRALTNITGNGVAAVFVSWWEGELDHDRLRANLSRNVDPSDVETAVTTG
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS5_STAAB
Sequence: MIVIVDYGLGNISNVKRAIEHLGYEVVVSNKQNIIDQAETIILPGVGHFKDAMSEIKRLNLDAILAKNTDKKMIGICLGMQLMYEHSDEGDASGLGFIPGNISRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGTDIPAIVQFNNYIGIQFHPEKSGTYGLQILRQAIQGGFIND
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP3_SCHPO
Sequence: MLPIGIFYQFYAYFALVLSIPILYMQLRARNIPCLLLLFWLTLTTLIYVVESAIWSNPYAETIRWMGYGLCDITSRIVTCSSIGIPASAFTLVLYLDTVIRRDHPLKRYENWIWHVCLSILLPLIIMAMMVPLESNRYVVICMNGCYSSFYQTWYTLLFFYIPPCLLSFGGLFFVSRIVVLYWRRQRELQQFFQRDSQLTSKRFLRLLCLAAVFFLGYFPLTIFMVVANGKLQQFLPFNHELVEAWHQESITYYPTTKVGLNDWVPPTVLYLMSLFFSTSGGWTEKVALILWSLLVWLPFTKNTALGRHAQFKLDCCKSIESTMAGKTLDSTDFKEKCLVLERQWSKSSIPSDNSSELQDAAKYV
What is the function of this protein?
Receptor for the peptide pheromone M-factor, a mating factor of S. pombe.  Pheromone signaling is essential for initiation of meiosis in S. pombe; M-factor signaling alone may be sufficient.
What are the official names of this protein?
Pheromone M-factor receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.