PharMolix/UniProtQA huggingface dataset:
Protein: KDSA_SHEPW
Sequence: MSNKTIDLGSIEIANDKPFVLFGGMNVLESRDLAMQIAETYAEVTQKLGIPYVFKASFDKANRSSVNSYRGPGMEEGLKIFEEIKSTFNLPLITDVHEVHQCAPVAEVVDIIQLPAFLARQTDLVVAMAKTGAIINVKKPQFLAPHEMRHIISKFNEAGNDEIILCERGSSFGYNNLVVDMLGMDEMKQSGYPVIFDATHALQKPGGRSDSAGGRRAQATELARSGMALGLAGLFIEAHPDPDNAKCDGPCALPLHQLENYLTQMKAVDDLVKSFAPIDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCL3_LEIHE
Sequence: VRDGYIAQPENCVYHCFPGSSGCDTLCKEKGGTSGHCGFKVGHGLACWCNALPDNVGIIVEGEKCHS
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  The dissociation is voltage-dependent.  This alpha-like toxin is highly toxic to insects and competes with LqhaIT on binding to insect sodium channels.  Differs from classical anti-mammalian alpha-toxins as it inhibits sodium channel inactivation in cell bodies of hippocampus brain neurons, on which the anti-mammalian Lqh2 is inactive, and is unable to affect Nav1. 2 in the rat brain, on which Lqh2 is highly active.  Moreover, its pharmacological properties are unique in that its binding affinity for insect channels drops >30-fold at pH 8. 5 versus pH 6. 5, and its rate of association with receptor site-3 on both insect and mammalian sodium channels is 4-15-fold slower compared with LqhaIT and Lqh2.
What are the official names of this protein?
Alpha-like toxin Lqh3, Lqh III, LqhIII.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYC2_RAT
Sequence: MGDAEAGKKIFIQKCAQCHTVEKGGKHKTGPNLWGLFGRKTGQAPGFSYTDANKNKGVIWTEETLMEYLENPKKYIPGTKMIFAGIKKKSEREDLIQYLKEATSS
What is the function of this protein?
Plays a role in apoptosis.  Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol.  Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity).
What are the official names of this protein?
Cytochrome c, testis-specific.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: FUR_STAAC
Sequence: MNTNDAIKILKENGLKYTDKRKDMLDIFVEEDKYINAKYIQQVMDENYPGISFDTIYRNLHLFKDLGIIENTELDGEMKFRIACTNHHHHHFICEKCGDTKVIDYCPIDQIKLSLPGVNIHKHKLEVYGVCESCQD
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_VIBPA
Sequence: MSIWQRVSFTHRFSQLPSAFYTLVEPQPLDNTRWVAWNGEFAQQFGLPAAQNDELLAVFSGQSEFEPFRPLAMKYAGHQFGVYNPDLGDGRGLLLAEIEHQNGTWFDIHLKGAGLTPYSRMGDGRAVLRSTIREYLCSEAMAGLGIPTTRALGMVVSDTPVYREKTEFGAMLIRMAETHVRFGHFEHLFYTNQLAEQKLLADKVIEWHFADCASAEKPYAAMFGEIVQKTADMIAYWQAYGFAHGVMNTDNMSILGQTFDYGPFGFLDDYEPGYICNHSDYQGRYAFEQQPRIALWNLSALAHALSPLVEREDLEQALSQFEGRLSQQFSRLMRSKLGLKTKIAEDGRLFESMFELLNQNHTDYTRFFRALSNLDKQPAQEVIDLFIDREAAQAWLDLYLARCELEVDEIGEPISAEQRSEQMRQTNPKYILRNYLAQLAIDKAEEGDFSEVHRLAEILRHPYDSQPEFEAYAKLPPEWGKKMEISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: OMP2A_BRUNE
Sequence: MNIKSLLLGSAAALVAASGAQAADAIVAPEPEAVEYVRVCDAYGAGYFYIPGTETCLRISGYVRYDVKGGDDVYTGSDRKGWDKGARFALMFNTNSETELGTLGTYTQLRFNYTSNNSRHDGQYGDFSDDRDVADGGVSTGTDLQFAYITLGGFKVGIDESEFHTFTGYLGDVINDDVVADGSYRTGKIAYTFTGGNGFPAVIALEQGGEDVDNDYTIDGYMPHVVGGLKYAGGWGSIAGVVAYDSVIEEWATKVRGDVNITDRFSVWLQGAYSSAATPNQNYGQWGGDWAVWGGAKFIATEKATFNLQAAHDDWGKTAVTANVAYELVPGFTVTPEVSYTKFGGEWKDTVAEDNAWGGIVRFQRSF
What is the function of this protein?
Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
What are the official names of this protein?
Porin Omp2a.
What is the protein family that this protein belongs to?
Belongs to the alphaproteobacteria porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: GPDA_CLOBA
Sequence: MSKVSFIGGGSFGTALAILLAEKGNTVSIYNRDKKVVDDININRRNDKYIKNLQVPSNIKAFDNLEKATEDAEYIVLAIPSHTIRSICKQLKNKIKQETIIISIAKGIEEHTDKRLSLVIKEELNNPIVVLSGPSHAEEVVLKLPTTLVVSSENMNAASEAQNLFMTSFFRVYTNEDLVGVEVGGAVKNIIALAAGILDGLGYGDNTKAALMTRGMKEISRIGSALGGKEETFYGLTGMGDLIVTCTSNHSRNRKAGLLIGSGMDVNKAIEKIGMVVEGVKACKAFYELKEKIGVSMPITDILYKVLFEKKDPKSGIEELMLREKKSEIF
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDP_SHEPW
Sequence: MSSLPALDIFLSDYQQAYLDTLGEHPRYYAQQQASECIVGDVDVETEEALQWKSVVRVDTGRFDNVEHALELSLHGDINAFYGSHFAASLMFDSQWGTGELLQAWSQSDFEHLQQNMIGHLMMKKKLKQEPTWFIGVFDDEDKMITVNNADGSVWIEIAGQAQSVKLADSLNSFISEVSPRVAPPVKLVEEVIPAYDHPGIWQRMKIMWRNLLGK
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: THIO2_DICDI
Sequence: MSRVIHISSNEELDKHLQAERLVIDFSAAWCGPCRAISPVFEKLSNEFVTFTFVHVDIDKLSGHPIVKEIRSVPTFYFYRNGAKVSEF
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin-2, Trx-2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: ZNF18_RAT
Sequence: MPVNLGQALGLLPFLAKAEDATFSGSDVIQQRELANPETARQLFRQFRYQVMSGPQETLRQLRKLCFQWLRPEVHTKEQILEILMLEQFLTILPGEIQMWVRKQCPGSGEEAVTLVESLKGDPQKLWQWISIQVLGQEIPFEKENSARCRGDKVEPALEAEPTVEVVPQDLPLQNTSSAPGELLSHGVKEESDLEPELALAASQLPARPEERPTRDQEVGTALLPSLQEEQWRHLDSTQKEQYWDLMLETYGKMVSGVAGISNSKPDLTNMAEYGEELVGLHLHSAEKMARAPCKEDRQENDKENLNLENHRDQGCLDVFDQAPGEAPPQTALSDFFGESEPHHFGGESVPEALENLQGEGTGAHLFPHERGSGKQLGQHIQSSSSGELSALWLEEKREASQKGQARAPMAQKLPTCRECGKTFYRNSQLVFHQRTHTGETYFHCRICKKAFLRSSDFVKHQRTHTGEKPCKCDYCGKGFSDFSGLRHHEKIHTGEKPYKCPICEKSFIQRSNFNRHQRVHTGEKPYKCTHCGKRFSWSSSLDKHQRSHLGKKPCP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 18, Zinc finger protein 535.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL17_MALP2
Sequence: MSYINKKGKTTSWRLMVIRQQVSEVIANNQITTTLTKAKETRKHVDRIITLAKKNTLASRRAAAAILLDTSISTKDQLIQKLFTDLQKKYTSRNGGYTRILKLGRRKGDNVEEAILQLV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ACT1_HELTB
Sequence: MCDDDVAALVIDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVFDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMSTAASSSSLEKSYELPDGQVITIGNERFRAPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMFPGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin CyI, cytoplasmic.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ATPG_PSET1
Sequence: MASGKEIKSKIGSIKNTQKITSAMEMVAASKMKRAQERVATSRPYAAKLRTVIGRVAQANLDFTHPFLEEREVKRVGYIVISTDRGLCGGLNSNEFKKVALDIKAWKEKGVSAEFATLGSKAAGFFQRFGGQVLAKKAGLGDKPSIQDIIGPVKVMLDAFSEGKIDRLFLVYNKFVNTMKQEPTVDQLLPLPKAEEEVSAHTWDYLYEPNPDAILEALLVRFVESQVYQGVVENAASEQAARMVAMKAATDNAGDLMDELQLIYNKARQAAITQEISEICSGSAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLMU_SODGM
Sequence: MSNRALSVVVLAAGKGSRMFSTLPKVLHPLAGKAMVQHVIDTAMRLGASRIHLVYGHGGELLRERLARQYAPLNWVLQAEQRGTGHAVQQTLTCLRDEEDVLILYGDVPLISPDTLQCLLAARPQGGIGLLTVTLDNPEGYGRIVRLNGEVAGIVEQKDASEQQRQIKEINTGILVAGGEDIKRWLGQLTNKNAQGEFYLTDIIAMAWHEGRKINAVQPTRQTEVEGVNNRLQLARLERLFQREQAERLLLAGVMLSDPDRFDLRGEFRHGQDVSIDTNVILEGQVTLGDRVIIGTGCVLKNVVIGDDVIISPYTVIEDARVAARSTLGPFARLRPGSELEEDAHVGNFVEMKQARLGKGSKAGHLSYLGDAEIGAQVNIGAGTITCNYDGANKHKTHIGDDVFVGSDSQLVAPVTIGRGATIGAGTTVTRDVAEGEMIISRIRQFPLANWTRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_PSEPG
Sequence: MARVKRGVIARKRHKKILKLAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQKKRQFRALWIARINAGARTNGLSYSRLIAGLKKASIEIDRKVLADLAVNEKAAFAAIVEKAKAVLA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TPSN_MOUSE
Sequence: MKPLLLLVAVALGLATVVSVVSAGPEAIECWFVEDAGGGGLSKKPATLLLRHGPRGPPPRPDLDPKLYFKVDDPAGMLLAAFRRYPAGASAPHCEMSRFIPFPASAKWARSLSPEQNCPRALDGDWLLVSVSSTLFSLSSLLRPQPEPLREPVVITMATVVLTVLTHNPAPRVQLGKDAVLDLRFAYAPSALEGSPSLDAGPPPFGLEWRRQHRGKGHLLLAATPGLAGRMPPAQEKATAFAAWDDDEPWGPWTGNGTFWLPAVKPSQEGVYLATVHLPYLQGQVSLELTVHKAPRVSLTPAPVVWAAPGEAPPELLCLASHFFPAEGLEVKWELRGGPGGSSRKVEGKTWLSTIRHHSDGSVSQSGHLQLPPVTAKQHGVHYVCRVYHSSLPASGRSADVTLEVAGFSGPSIEDGIGLFLSAFLLLGLLKVLGWLAAYWTIPEVSKEKATAASLTIPRNSKKSQ
What is the function of this protein?
Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
What are the official names of this protein?
Tapasin, TPN, TPSN, TAP-associated protein, TAP-binding protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: MIAA_BACCN
Sequence: MEEKQREKVVVIIGPTAVGKTKLSIELAKALNGEIVSGDSMQIYRTMDIGTAKVTADEMEGIPHYMIDIKDPEDSFSVAEFQELVRGHIREITKRGKLPIIVGGTGLYIQSVLYDYQFTDEAGDTAYRERMEKLAEEQGVEFVHKKLEEVDPESAKRIHANNVRRVIRALEIFQTTGKKMSEQLEKQKNELLYDVVLIGLTMDRTMLYDRINLRVDLMMEQGLEQEVKRLYQNGVRDCQSIQAIGYKELYRYFAGATSLEEAISQLKTNSRRYAKRQLTWFRNKMDVAWFDVTDGEKTAEILRYIEGKLQLKSNNN
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: UFL1_NEMVE
Sequence: MADWDEIKKLAADFHRVQLTSTAHKLSERNCIEIVQKLINTGLLEVIYTTDGKEYLTPQQLEREIKDELFVHGGRFFLLNLVDLQQIINVDLSHVDNKVSEILRHDKSLVLIQGDLIDKDYLDRMAEEINETLQEAGQVFIAELSKTFSLPTDFMLEVVESRLDIQIMGKLDQMDRNVLYTHAFIARQTARMRGVLSAITRPTQFSNIISKYGFQEKLFYSVIGDLLSSKRIMGSTQGRQDKISFVPDVYTQAQNNWVDDFFKQNGYVEYDALTRLGITDGKQFLKRRYHGNEIFLPTCCVGERVLDQADAAIDDALSSGTWVDIMPHLPTPFTPDDAEQLLQHCLKTPGRSTAHVYCSSIVASDKFVEACKAPFETRMHAKAKKDAAESPALFAELSKKDLASLKGGGGGADRREARKEDRRKTASSGGKGGGSVGGRGGRETKTKKVKKKDFRNRNDEDDTNEADSRSNPDELQFMTTEEIAEVLRKDRPDIDDDFLEELAQEMHRPLTRAYQQVARAVLQSSGDKKRKSHAEIQEKVNALWANAKLFDKSINLFPEDVQVHLSRHLLRTVCTDITNLMVNMLAADHMLAVTDETTITPETRLKIIKKMPEEIKAPLTKLNSSLTAKETEEFFAQFDLVAGQGLCELMIKKLDKKKERQISIERRAALQEQLRHEDEPAMTLHLAVSLLFQHFTSSLLHAPGRCVPQIVALLAEHVTPEQHEILLRCQSLVVKQLTRSGSDEVEEEAGDEHENEAGVEKSTAVLLEEGMREIKKMVLELKKDNSKNES
What is the function of this protein?
E3 UFM1-protein ligase that mediates ufmylation of target proteins.
What are the official names of this protein?
E3 UFM1-protein ligase 1 homolog, E3 UFM1-protein transferase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UFL1 family.
Protein: RECO_PARXL
Sequence: MTLNSDADPDDPEPAAPARDLSKPASKPARSTRKSSSAKSAQGAEGEPRKTPGRRAPRTPASDYRIAEQPAFVLHSYPYRETSLIIDVLSRDHGRLALVAKGAKRPHSALRGVLQTFQPLALSWSGKSEVRTLTGAEWVGGMLPLTGGALLCGFYVNELLVKFCAREDPHPQLFHHYVVTMTRLAHDEPPVQVLRSFERVLLRETGYAMALDRTVARKAVLAEGRYVFDPERGVREAADDLPAQWPVIAGQTLLDMEQDDYHRAQTVAQSKTLMRFLLNTYLGGTPLATRQILIDLQNL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RLMKL_YERPS
Sequence: MNSLFASTARGLEELLKSELEALGAHDCKIVQGGVHFQGDDRLMYQSLLWSRLASRILLPLNEFKVYSDLDLYLGVQAIDWPSIFGVDKTFAVHFSGVNDEIRNSQYGALKVKDAIVDSFTRKMDQRPTVAKQQPDIRVNVFLQRDMASVALDLSGEGLHQRGYRDLTGQAPLKENLAAAIIQRSGWQPGTPMVDPMCGSGTLLIEAAMMASDRAPGLHRGHWGFTAWNAFNEALWRELTTEAQVRARRGLLETSSRFFGSDIDRRVIEMARANARRAGVAELITFNANDISKLVNPLPEGPVGTVISNPPYGERLESEPALIALHNMFGRMMKTAFGGWRLSLFSASPELLSCLQLRADREFKAKNGPLDCVQKNYQLTANPQGAGGALVAEDYANRLRKNVKKLDKWAKQQGIECYRLYDADLPDYNVAVDRYGSKVVVQEYAPPKTIDPQKARQRLFDVINATLAVLELPSNQLVLKTRERQKGKNQYEKLAQKGEFLLVSEYNAKLWVNLTDYLDTGLFLDHRIARQMLGKMSQGKDFLNLFAYTGTASVHAGLGGARSTTTVDMSRTYLEWAEKNLRANGLTGQQHRLIQADCLSWLSNTDEQFDVIFIDPPTFSNSKRMETTFDVQRDHLVLMKELKRLLRRKGTIMFSNNKRGFQMDLAGIAALGLEAKEITALTQSEDFARNRQIHNCWLVTHSQEEK
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAC_STRPJ
Sequence: MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPNEETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRVANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTTHPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRVAQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKVEAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INMT_HUMAN
Sequence: MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLIDIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGNSGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAALCNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQSYSVTNAANNGVCFIVARKKPGP
What is the function of this protein?
Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide.  Plays an important role in the detoxification of selenium compounds (By similarity).  Catalyzes the N-methylation of tryptamine and structurally related compounds.
What are the official names of this protein?
Indolethylamine N-methyltransferase, Indolamine N-methyltransferase, Aromatic alkylamine N-methyltransferase, Amine N-methyltransferase, Arylamine N-methyltransferase, Thioether S-methyltransferase, TEMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LON4_SORC5
Sequence: MSQLRSGASAPRSPFPLLPLRTGVLFPGTVLTLPVGRPRSVALLNAVHAGDVIGVIAQRDPKREDPRREDLHDIGTFARVVDISRVSNGYRLVIEGLDRFALSALVETEPTWRAEGTLAPEFLGDAEEARLLAASLRERAREVGPKTGTNLAEIAATSRAEPGVFADQVAGALGLPTEKEMEVLSELRVVPRLQRVAGLLAEASALADLKKKIDGDVRRELGKGQREVILREQLRAIQKELAGGEEGEDELSALRRRLDEAGLPEEARAVADRELRRLESVGPQSAEHNVIRTYLEWIADLPWSARAEVKDDLDAVKAKLDEEHRGLDDVKRRILEHMAVLKLTGKARATILCFAGPPGVGKTSLGQSIADATGRPFVRISLGGVHDEAELRGHRRTYVGALPGRIVHALKKAKVKNPIVLLDEVDKLGAGWRGSPEAALLEVLDPEQNRTFVDHYLELPFDLSEVVFLCTVNDLGALSAPLRDRLEVIELSGYTPDEKIAIARSHLVPKQLKEHAIDPGSLSITDEALAAIVRDYTREAGVRQLGREIKKLCRAVALEIARAADGKAPRVVVEASDLGTYLGKVRFFSDVAERTSVAGVATGLAWTPVGGDILFIETSRMPGKGRVEITGQLGDVMKESAKAALTYVRSHAIELGVDTAKLEAEDLHIHVPAGGVPKDGPSAGVTMFTALTSLLSARRVRSDTAMTGECTLRGRVLPVGGIKSKVLAAHRAGIKRVVLPQKNARDAEEIPKEVRAELELIFVEDMSQVIAAALEEAPIEAAGTGGVTGAAAGEPAAAA
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease 4, ATP-dependent protease La 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHB_CHLPD
Sequence: MRLAFWLYEGTALHGISRITNSMKGVHTVYHAPQGDDYITATYTMLERTPDFPGLSISVVRGRDLAQGVSRLPSTLQQVDHHYSPDLTVIAPSCSTALLQEDLNQLAAHSGVPSEKLLVYALNPFRVSENEAADGLFTELVKRYAVAQEKTPTPSVNLLGFTSLGFHLRANLTSLRRMLEALGIAVNVVAPWGSGIDDLAKLPAAWLNIAPYREIGATAAAYLDETCGMPAMYEAPIGVEPTTAWLRKLLDEINRIAGQKGLSRLAMPAPRAFSLDGLSAPSGVPWFARTADMESFSNKRAFVFGDATHTVALVKFLRDELGMQIIGAGTYLERHADWVRKELDGYLPGELMVTDRFQDVAKFIDDQMPDLVCGTQMERHSCRKLDVPCMVICPPTHIENHLLGYYPFFGFDGADVIADRVYLSCKLGLEKHLIDFFGDAGLEYEESDDAAKAEPDQPVSNAHGHTESKTVSQGEPIASDEGGISWSDEAETMLKKVPFFVRKKVRKNTEDFALGIGESCVTAEVFRKAKESLGG
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: RU1C_SCHPO
Sequence: MPRYLCDYCQVWLTHDSQSVRKAHNAGRAHIQNVQDYYTKVAQEEAQKQLEERASSGFLKKGNGSLDLPYAYAFPPKYNVFNLGCPPPPYIVSANTYMAPKGMNAMNAAAFVPMMPAVNLTNQVAFSAPQTTASSNTQLTQQQQSLPQTNEHQRARTHSNANNHFTKTHHQGQRSHQRFVRA
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  usp103/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPG_PARDP
Sequence: MSHNPIRPWRNIDRRNSRRIMVGNVPVGGDAPISVQTMTNTDTSDVRATLDQIIRAADVGADIVRVSTPDQDSTRALREICRESPVPIVADIHFHYKRAIEAAEAGAACLRINPGNIGDATRVREVIKAARDHGCSIRIGVNAGSLEKHLLEKYGEPCPDAMVESGLDHIRILQDNDFHEFKISVKASDVFLAAAAYQQLADATDAPIHLGITEAGGLTAGTVKSAIGLGNLLWMGIGDTIRVSLSADPVEEVKVGFEILKSLGLRTRGVQIISCPSCARQGFDVIKTVEILEKRLEHIKTPMSLSIIGCVVNGPGEALMTDIGFTGGGAGSGMVYLAGKQNHKMTNAQMVDHIVELVEKRAAEIEAAQSAAAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.