PharMolix/UniProtQA huggingface dataset:
Protein: SYT_BACFR
Sequence: MIKITFPDGSVREYNEGVNGLQIAESISSRLAQDVLACGVNGEIYDLGRPINEDASVVLYKWEDEQGKHAFWHTSAHLLAEALQELYPGIQFGIGPAIENGFYYDVDPGEAVIKEADLPAIEAKMAELVAKKEAVVRRDIAKGDALKMFGDRGETYKCELISELEDGHITTYTQGDFTDLCRGPHLMTTAPIKAIKLTSVAGAYWRGHEDRKMLTRIYGITFPKKKMLDEYLALMEEAKKRDHRKIGKEMQLFMFSDTVGKGLPMWLPKGTALRLRLQDFLRRIQTRYDYQEVITPPIGNKLLYVTSGHYAKYGKDAFQPIHTPEEGEEYFLKPMNCPHHCEIYKNFPRSYKDLPLRIAEFGTVCRYEQSGELHGLTRVRSFTQDDAHIFCRPDQVKGEFLRVMDIISIVFRSMDFDNFEAQISLRDKVNREKYIGSDENWEKAEQAIIEACEEKGLKAKIEYGEAAFYGPKLDFMVKDAIGRRWQLGTIQVDYNLPERFELEYMGSDNQKHRPVMIHRAPFGSMERFVAVLIEHTAGKFPLWLTPEQVVILPISEKFNEYAEKVKTYLKMKEIRAIVDDRNEKIGRKIRDNEMKRIPYMLIVGEKEAENGEVSVRRQGEGDKGTMKFEEFGEILNEEVQNMINKW
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_BACCN
Sequence: MKKFILASGSPRRKELLELANVPFEVVVSEVEETIGAYSSPADIVMALALQKASAVAETHEESIVLGADTIVTYDSRILGKPKDAAEAKEMLQLLSGKTHEVYTGVALMSKEKTVTFYERTEVTFWELTEEEIDVYIATKEPLDKAGSYGIQGKGAIFVQHIQGDYYSVVGLPIARLVRELKQFDSGASHA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIB_PECCP
Sequence: MVTVNRLVLSGTVCKTPIRKVSPSGIPHCQFVLEHRSTQEEAGLSRQAWCRMPVIVSGLSSQAVTHSITVGTQLTVHGFISCHQGRNGLSKIVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: PETL_PIPCE
Sequence: MPTITSYFGFLLAALTITSALLIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FORD2_AQUAE
Sequence: MYFVADVKEKECAQYNCKQCVLFCPEPNCLNFKASTNSAWVWYDRCKGCEICVYVCSDLLKRHCIEMVMVTPKATAKS
What are the official names of this protein?
Ferredoxin oxidoreductase 2 subunit ForD, Ferredoxin oxidoreductase 2 subunit delta.
Protein: YJGA_ECO24
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: HEPN1_HUMAN
Sequence: MGNWGLGIAPWVDGESELEFRRLGMQGPLEALRRREWNTQRASFSFSFLIALSPHTVDYCHSYELFNRRWHGHVLATQRPSLFILMLV
What are the official names of this protein?
Putative cancer susceptibility gene HEPN1 protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MERB_KLEPN
Sequence: MKLAPYILERLTSVNRTNGTADLLVPLLRELAKGRPVSRTTLAGILDWPAERVAAVLEQATSTEYDKDGNIIGYGLTLRETSYVFEIDDRRLYAWCALDTLIFPALIGRTARVSSHCAATGAPVSLTVSPSEIQAVEPAGMAVSLVLPQEAADVRQSFCCHVHFFASVPTAEDWASKHQGLEGLAIVSVHEAFGLGQEFNRHLLQTMSSRTP
What is the function of this protein?
Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate.  One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.
What are the official names of this protein?
Alkylmercury lyase, Organomercurial lyase.
What is the protein family that this protein belongs to?
Belongs to the MerB family.
Protein: MALQ_MYCTU
Sequence: MTELAPSLVELARRFGIATEYTDWTGRQVLVSEATLVAALAALGVPAQTEQQRNDALAAQLRSYWARPLPATIVMRAGEQTQFRVHVTDGAPADVWLQLEDGTTRAEVVQVDNFTPPFDLDGRWIGEASFVLPADLPLGYHRVNLRSGDSQASAAVVVTPDWLGLPDKLAGRRAWGLAVQLYSVRSRQSWGIGDLTDLANLALWSASAHGAGYVLVNPLHAATLPGPAGRSKPIEPSPYLPTSRRFVNPLYLRVEAIPELVDLPKRGRVQRLRTNVQQHADQLDTIDRDSAWAAKRAALKLVHRVPRSAGRELAYAAFRTREGRALDDFATWCALAETYGDDWHRWPKSLRHPDASGVADFVDKHADAVDFHRWLQWQLDEQLASAQSQALRAGMSLGIMADLAVGVHPNGADAWALQDVLAQGVTAGAPPDEFNQLGQDWSQPPWRPDRLAEQEYRPFRALIQAALRHAGAVRIDHIIGLFRLWWIPDGAPPTQGTYVRYDHDAMIGIVALEAHRAGAVVVGEDLGTVEPWVRDYLLLRGLLGTSILWFEQDRDCGPAGTPLPAERWREYCLSSVTTHDLPPTAGYLAGDQVRLRESLGLLTNPVEAELESARADRAAWMAELRRVGLLADGAEPDSEEAVLALYRYLGRTPSRLLAVALTDAVGDRRTQNQPGTTDEYPNWRVPLTGPDGQPMLLEDIFTDRRAATLAEAVRAATTSPMSCW
What are the official names of this protein?
4-alpha-glucanotransferase, Amylomaltase, Disproportionating enzyme, D-enzyme.
What is the protein family that this protein belongs to?
Belongs to the disproportionating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBTN1_BOVIN
Sequence: MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDQYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGTFDSHVQ
What is the function of this protein?
May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.
What are the official names of this protein?
Rhombotin-1, LIM domain only protein 1, LMO-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: VL2_OVPVD
Sequence: MPPLKRVKRANPYDLYRTCKRWKCPLMSFLKVEGKTVADKYCSMGSMGVYWRLALHGSGRPTQGGYVPLRGGGSSTSLSSRGSGSSTSISRPFAGGIPLETLETVGAFRPGIIEEVAPTLEGVLPDAPAVVTPEAVPVDQGLSGLDVAREVTQESLITFLQPEGPDDIAVLELRPTEHDQTHLISTSTHPNPLFHAPIQQSSIIAETSGSENIFVGGGGVGSTTGEEIELTLFGQPKTSTPEGPINRGRGIFNWFNRTYYTQVPVEDPDEIAAAGSYVFENALYDSKAYKHEQQPWLSRPQDAPEFDFQDAVRLLQGPSGRVGWSRIIRPTSIGTRSGVRVGPLYHLRQSFSTIDEPETIELIPSTVDEEEVLTGVPESAEGPDAEYSDIDLQSIGSDEPLLGTGIIYPLVGGGQIFLCMHRAPVGWSSGTYINHEGQSRDDGEYVIDNGGQSNITPTVVIDGSIALSLEYFRHYYLHPSLLRRKRKRNPIFI
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: RSMG_PHOV8
Sequence: MELILKYFPNLSEQQKTQFAALYDLYTDWNSKINVISRKDITNLYEHHVLHSLGIAKVINFTPDTQIMDLGTGGGFPGIPLAILFPEVQFHLVDSIGKKVKVATEIANAIGLKNVTFRHCRAEEEKRKFDFVVSRAVMPLGDLIKIIRKNIRQEQHNALPNGLICLKGGELEQETMPVKHKTMLYDLKNEFTEDFFKTKKVVYVTISGL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHD_SHISS
Sequence: MGIMHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NARF_DROYA
Sequence: MSRLSRALQLTDIDDFITPSQICIKPVEIDKARSKTGAKIKIKGDSCFEESESGKQKLNKVEITLQDCLACSGCITSAEGVLITQQSQEELLRVLQENSKKKATEDWDNVRTIVFSVATQPLLSLAHRYQIGVEDAARHLAGYFRSLGGNYVLSTKVADDIALLECRQEFVERYRENENLTMLSSSCPGWVCYAEKTHGNFILPYVSTTRSPQQIMGVLVKHILAEKLNIPASRIYHVTVMPCYDKKLEASRDDFFSKTNNSRDVDCVITSVEVEQLLGEAQRTLSQFDPLDLDWPWSNVRPDLMVWAHEKTLSGGYAEHVFKFAAKQIFNEVPTNELEFKQLKNRDFREIILKKNGNTVLKFAIANGFRNIQNMVQKLKRGKVSNYHFVEVMACPSGCINGGAQIRPTTGQHVRELTRKLEELYHNLPLSEPENSLTKHIYKDFLDGFQTEKSYELLHTSYHDVVSELSISLNINW
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins (By similarity).
What are the official names of this protein?
Probable cytosolic Fe-S cluster assembly factor GE22682.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: NDC80_EMENI
Sequence: MSQDTGLFSIKRPRETLGSVQNFSSLPQPSSALKRTSSIGYQNPPFTSQHTRSMSLLNSVGRPQQPNFQRSSSGGFGADPGLSSVRRSVSSNVFHGTSAGRPSFAPGSMSSNPASQSLQRRSSVFSRPSTGGAMGHQSFFTQVPSAAGVPRDPRPLRDRSFQARIAQELLEYLTHNNFELEMKHSLGQNTLRSPTQKDFNYIFQWLYHRIDPGYRFQKAMDAEVPPILKQLRYPYEKGITKSQIAAVGGQNWPTFLGMLHWLMELAQMMDRFAMGEYDEACAEMGVDVSGDRIIFRFLTGAYHDWLQGGEEEDDDAAAQRLIPHIELMAQEFEKGNEKYVQEMQVLDAENRALRDQIEELEKNAPDMAKLDKQFRILEDDKRKFEDYIQNVQGKIEKYESRIAFLEDEIRKTESELQAAEEERAGLQASVDQQGLTIQDIDRMNTERDRLQRSLDDAVSRLEETHARVMAKESEASAKLEDLEELVKTYNTLGYQNSLIPSTAVNANGQEYELGLNVNERSFSTSQIGGIPSRISPEADRLLAEPFTGYHPAHLLNLDLRGIVRSNLQALRKEINERRKRGIDADLERRNLLDNIKEAMDEKRSEVEALEHKRRTAEEEFERLKEVTTTQKLASDAQIEKMEKELAKMRATMSESVQLMEQREMNTNIEYEQLTLRANALREELHTNVESMLNDVIRFKVHIQKGLEDYENFVVDEVEQELGGDTQLDEDAPMSTEEL
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein ndc80.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: O16O2_CONTE
Sequence: MKLTCVVIVAVLFLTAWTFVTAAPHSSNALENLYLKAHHEMNNPEDSELNKRCYDSGTSCNTGNQCCSGWCIFVCL
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like TxO2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IF1_STAA1
Sequence: MAKQDVIELEGTVLDTLPNAMFKVELENGHEILAHVSGKIRMNYIRILPGDKVTVEMSPYDLTRGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BASS4_ARATH
Sequence: MAIASTLASTQNPFLCLRQPPSPGNRSVVFRRCQDPCGRRWISRSIRACQPSDKVSGQFPFDFMYSSMLIPSSCGEWNRIHLGGDGGISASAQRLYFGKELLSFASDNFLPLALVSGVGLGFANPTLGCLADKYSFTKISTCGIFIISGLTLRTEAIGAAVKGWPLGLFGLISILLLTPSFSRLIMLVQLQPRELVTGLGIFCCMPTTLSSGVALTHLAGGNAALALAVTVASNLLGILTIPFWVSRYIAGGVGVSFPTDQLFRSLIVTLLIPLIIGKVIRESFKGFANFVDNNRKLFSKINAICLSLVPWIQVSRSRSLLLSVQPKVFLAAVGIGILLHLSLLAFNAVSIRILSGLTGGSKSSKENSTAVLLVSSQKTLPVMVAVVEQLGGAFGETGLLVLPCVAAHLNQIMIDSVLVNLWLRRGKDTSTKVKTA
What is the function of this protein?
May function as sodium-coupled metabolite transporter across the chloroplast envelope.
What are the official names of this protein?
Probable sodium/metabolite cotransporter BASS4, chloroplastic, Bile acid transporter 4, Bile acid-sodium symporter family protein 4.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Plastid, chloroplast envelope.
Protein: MURQ_LACAC
Sequence: MEIKNLTTEQRNPASIHIDTVSTVEMVKIMNEEDQKVALAVGNQDEQIARAIDEAANRYKKGGRLIYLGAGTSGRLGVLDAAELVPTYGIKPERAIGLIAGGPGAMYKAVEGAEDDTNLGAEDLKDLNLNSQDIVLGLAASGRTPYVIGGLEYANQIGAFTISIACVKDSEIGKHAEVAIEAVVGPEIVTGSTRMKSGTAQKMILNMISTGVMIRQGKVFENVMIDVMPTNSKLVDRASRIISAVTDATQEEALQTLKKAENNVPLAITMIKTESNKDEAQKLLEQYNGNVSEVIKNN
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: TRPF_NEIG1
Sequence: MRKIRTKICGITTPEDALYAAHAGADALGLVFYPQSPRAIDIIKAQKIAAALPPFVSVVALFVNESAQNIRRILAEVPIHIIQFHGDEDDAFCRQFDRPYIKAIRVQTASDIRNAATRFPNAQALLFDAYHPSEYGGTGHRFDWTLLAEYSGKPWVLAGGLTPENVGEAVRITGAEAVDVSGGVEASKGKKDPAKVAAFIATANRLSR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: CHLE_MACMU
Sequence: NIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHL
What is the function of this protein?
Esterase with broad substrate specificity.  Contributes to the inactivation of the neurotransmitter acetylcholine.  Can degrade neurotoxic organophosphate esters (By similarity).
What are the official names of this protein?
Cholinesterase, Acylcholine acylhydrolase, Butyrylcholine esterase, Choline esterase II, Pseudocholinesterase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PP1GB_XENLA
Sequence: MADVDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNASRPVTPPRGIITKQAKK
What is the function of this protein?
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.  Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis (By similarity).  Promotes nuclear envelope reassembly by targeting nuclear membrane vesicles to chromatin at the end of mitosis.  Acts by dephosphorylating membrane proteins such as lamin B receptor (lbr) to regulate the binding of membrane proteins to chromatin (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit B, PP-1G-B, Protein phosphatase 1 zeta, xPP1-zeta.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cleavage furrow. Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome, centromere, kinetochore. Nucleus speckle. Midbody. Mitochondrion.
Protein: RL13_PROM0
Sequence: MNKTITPSLETIERNWFLVDAKDKTLGRLATEIATVLRGKNKPTFTPHLDTGDFVIVVNAEKVEVTGKKASQKLYRRHSGRPGGMKIEKFESLQERIPERIIEQAVKGMLPHNSLGRQQFKKLKVYKGADHPHAAQNPVLLNS
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CACO1_PONAB
Sequence: MEESPLSRAPSRGGVNFLNVARTYIPNTKVECHYTLPPGTMPSASDWIGIFKVEAACVRDYHTFVWSSVPESTADGSPIHTSVQFQASYLPKPGAQLYQFRYVNRQGRVCGQSPPFQFREPRPMDELVTLEEADGSSDILLVVPKATVLQNQLDESQQERNDLMQLKLQLEGQVTELRSRVQELERALATARQEHTELMEQYKGISRSHGEITEERDILSRQQGDHVARILELEDDIQTISEKVLTKEVELDRLRDTVKALTREQEKLLGQLKEVQADKEQSEAELQVAQQENHRLNLDLKEAKSWQKEQSAQAQRLKDKVAQMKDTLGQAQQRVAELEPLKEQLRGAQELATSSQQKATLLGEELASAAAARDRTIAELHRSRLEVAEVNGRLAELGLHLKEEKCQWSKERAGLLQSVEAEKDKILKLSAEILRLEKAVQEERTQNHVFKTELAREKDSSLVQLSESKRELTELRSALRVLQKEKEQLQEEKQELLEYMRKLEARLEKVADEKWNEDATTEDEEATAGLSCPAALTDSEDESPEDMRLPPYGLCEHGDPGSSPAGPREASPLVVISQPAPISPHLSGPAEDSSSDSEAEDEKSVLMAAVQSGGEEANLLLPELGNAFYDMASGFTVGPLSETSTGGPATPTWKECPICKERFPAESDKDALEDHMDGHFFFSTQDPFTFE
What is the function of this protein?
Seems to enhance inorganic pyrophosphatase thus activating phosphogluomutase (PMG).  Probably functions as component of the calphoglin complex, which is involved in linking cellular metabolism (phosphate and glucose metabolism) with other core functions including protein synthesis and degradation, calcium signaling and cell growth (By similarity).
What are the official names of this protein?
Calcium-binding and coiled-coil domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CALCOCO family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between nucleus and cytoplasm.
Protein: CIB2_RAT
Sequence: MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHARFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLELTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
What is the function of this protein?
Calcium- and integrin-binding protein that plays a role in intracellular calcium homeostasis (By similarity).  Acts as a auxiliary subunit of the sensory mechanoelectrical transduction (MET) channel in hair cells (By similarity).  Essential for mechanoelectrical transduction (MET) currents in auditory hair cells and thereby required for hearing (By similarity).  Regulates the function of hair cell mechanotransduction by controlling the distribution of transmembrane channel-like proteins TMC1 and TMC2, and by regulating the function of the MET channels in hair cells (By similarity).  Required for the maintenance of auditory hair cell stereocilia bundle morphology and function and for hair-cell survival in the cochlea (By similarity).  Critical for proper photoreceptor cell maintenance and function (By similarity).  Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (By similarity).
What are the official names of this protein?
Calcium and integrin-binding family member 2.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, stereocilium. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Cell membrane, sarcolemma. Note=Colocalized with ITGA7 at the myotendinous junctions (MTJ) and at the neuromuscular junctions (NMJ). Localizes in the cuticular plate along and at the tip of the stereocilia of vestibular sensory hair cells.
Protein: LEUD_RHOP5
Sequence: MDKFTTLEGVAAPLKIINVDTDMIIPKQYLKTIKRTGLGKGLFSEQRYNDDGSENPDFILNKPAYRGAKILVAGDNFGCGSSREHAPWALLDFGIRCVISTSFGDIFYNNCFKNGVLPIRVEQADLDRLFDDAERGSNATVTIDLPNQEIRGPDGGTVKFEIDPFRKHCLINGLDDIGLTLEKKASIDSYEAKAKTERAWA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RRAAH_AZOVD
Sequence: MQYVTPDLCDAYPELVQVVEPMFSNFGGRDSFGGEIVTIKCFEDNSLVKDQVDTDGKGKVLVVDGGGSLRRALLGDMLAEKAARNGWEGLVVYGCIRDVDVIAQTDLGVQALATHPMKTDKRGIGDLNVPVTFGGVTFRPGEYLYADNNGIIVSPQPLKMPE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: GPSB_STRZT
Sequence: MTSIIFSAKDIFEQEFGREVRGYSKVEVDEFLDDVIKDYETYAALVKSLRQEIADLKEELTRKPQVSSAPSPSHPDPIDVAASSSMTNFDILKRLNRLEKEVFGKQILDNTDL
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.