PharMolix/UniProtQA huggingface dataset:
Protein: PRO_ADE03
Sequence: MTCGSGNGSSEQELKAIVRDLGCGPYFLGTFDKRFPGFMAPDKLACAIVNTAGRETGGEHWLAFGWNPRYNTCYLFDPFGFSDERLKQIYQFEYEGLLRRSALATKDRCITLEKSTQSVQGPRSAACGLFCCMFLHAFVHWPDRPMDGNPTMKLVTGVSNSMLQSPQVQPTLRRNQEVLYRFLNTHSSYFRSHRARIERATAFDRMDMQ
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: ANMK_PROM1
Sequence: MRVLGLMSGTSADGIDAVLVDFTGDPSKPKWQILNTFSYEYPSSIREKIIQVGQGLKISSKDWLELAEEITELNAFAARTCDPDSTAEVVGCHGQTLFHRSVKKSKRGGSLQILLGPLLANLLDQIVIYDFRSKDIASGGHGAPLVALVDEALVGRLYGWRGVLNLGGIANLTIIPPKTGIDKTSQCLGWDCGPANSLVDLAVKESTNSSLTFDENGSLASLGIPKLEIIDKWLRDPFFYLEPPRSTGREQFGFQYLQKRKKELGDISKEDLISTLTTFTASIISQDLDNLFKFKQIRLIELLVAGGGSKNLFLMRQLQKQCCGVHVRPINEIGVPSQYREALVFATLSWWNFLGKKVNPKYITGAKKPILYGVRVDP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: BAP18_MOUSE
Sequence: MTSASTKVGEIFSAAGAAFTKLGELTMQLHPVSDSSPAGAKWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKTTVKRKVYEDSGIPLPAESPKKGPKKMTSGVLSPPNAPPPSSSSVPEAGVPPIKKQKADVTLSALNDSDANSDLVDVEGLGETPPAKKLNFDQA
What is the function of this protein?
Component of chromatin complexes such as the MLL1/MLL and NURF complexes.
What are the official names of this protein?
Chromatin complexes subunit BAP18, BPTF-associated protein of 18 kDa.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECY_NEOYE
Sequence: MSQKSDLRNRIIFTLFLLVLARLGIFIPVPGIDHDAFYASVEKNTLVNFLNIFSGGGFSTIGIFALGIVPYINSSIVMQLLTKIVPNLEKLQKEEGELGRQKITQITRYLALGWATLQSGAISIWVKPYVFNWNFAFVCESVLALTAGSMIIMWLSELITEKGIGNGASLLIFQNIVSGLPKNFTQSFFDASYSNASLKFGLFIAIFLLMIIITICVQEGTRRIKIISARQLGKSSILDPNSYLPLKLNQGGVMPIVFASASMALPSYLTQIIQNKTLLQILYLFCPNGSLYLLLYCALILFFSYFYTSIVMNPEDIAINLKKMGASIPNIRPGQATIDYLQVILNRLTFLGASFLFTVALIPFIIEKVTQIQNLRGLGATSLLILVGVAIDTAKQIQTYVISKKYDSMTK
What is the function of this protein?
The central subunit of the protein translocation channel SecYE.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: METK2_SOLTU
Sequence: METFLLTSESVNEGHPDKLCDQVSDAILDACLEQDPESKVACETCTKTNMVMVFGEITTKANVDYEKIVRDTCREIGFISADVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKKPEEIGAGDQGHMFGYATDETPELMPLTHVLATKLGAKLTEVRKNKTCPWLRPDGKTQVTVEYKNDNGAMVPIRVHTVLISTQHDETVTNDQIAQDLKEHVIKPVIPAKYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVASGLARRCIVQVSYAIGVAEPLSVFVDTYKTGTIPDKDILVLIKENFDFRPGMMSINLDLLRGGNFRYQKTAAYGHFGRDDPDFTWETVKVLKPKA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 2, AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_ECOL6
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWCEDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RP54_HELPY
Sequence: MAILRANLSPKNKLNATLKGWLPILQSELEDLEEVLKQNALDNPLIKIENKRIKNFSDRFSAKKSSDHLENFATASKSLFETLEAQIIPPLFPTETSQKIAMDIISGLNNEGYFEENIEERARILGVESEVYEKVRKRFSYLNPAGIGAKDVKESFLFQLESRELDDNELYEETRKIILNLEKHHEFSKDFYYEKALKILKSFKNPPAIEFLEKEIEVIPELFIVEVDNGIIVRLNDESYPTISLEENRFKDSGYLKEKLKEAKDLIDALNLRKATIYKIGLMLLEYQYDFFKGKELRPLKLLDLANEFNHSVSTISRAISNKYLACERGVFPIKHFFSIALDNSETSNAVIKDYLLELIKNEDKKEPLSDAKILELIEEKFHLKMVRRTITKYRQLLNIASSSERKRLYLMRA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
What are the official names of this protein?
RNA polymerase sigma-54 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-54 factor family.
Protein: RL24_ECO8A
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: YJ047_YEAST
Sequence: MKIKISIEISLSLLSEHYKRNENCISNMLVIGEGPRGETIVERF
What are the official names of this protein?
Uncharacterized protein YJL047C-A.
Protein: LHB2_RHOCA
Sequence: MTDDKAGPSGLSLKEAEEIHSYLIDGTRVFGAMALVAHILSAIATPWLG
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-800/850 beta chain, Antenna pigment protein beta chain, LH-3B.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: CALM_PENDC
Sequence: MNPVNTKPYQLSADATWFVTGCSTGIGRAIASHVASQPGHRLIATARDPSSLSYLDDDNPAILKLAMDVTNPSSVNAAFKAAADYFGDKYYIDVVVNNAGYSLSGDTESVTEHEMHDEFETNFFGTVRVTLKAIEVMRQSKDHRGGLIFNISSLAGICAFPGHAFYHASKFAVEGWSESVAREMHPDWNIHFCIVEPSAVKTNFETTSKKRTQPHEAYAGADMPARQLETFVKKGLEAGVGFEPSAVANVLYKVASRNEKVPLRLPLSATAVKLITAKLQVQLQDLETVSELSAIDVHQVQFKV
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of calbistrin A and related compounds.  Calbistrin A is a secondary metabolite with an interesting structure that was recently found to have bioactivity against leukemia cells.  It consists of two polyketides linked by an ester bond: a bicyclic decalin containing polyketide and a linear 12 carbon dioic acid structure (PubMed:30598828).  The polyketide synthase calA is probably responsible for forming the decalin moiety.  Because calA lacks a designated enoylreductase (ER) domain, the required activity is provided by the trans-enoyl reductase calK (PubMed:30598828).  Following release from the PKS, calF then probably catalyzes the oxidation and the subsequent Diels Alder cycloisomerization that lead to the formation of the decalin moiety (Probable).  The decalin polyketide backbone includes two C-methyl groups, at C7 and C11 in backbone, of which the C7 position is probably methylated by the methyltransferase domain of calA.  A candidate for adding the methyl group at C11, if not done by CalA, is the cluster methyltransferase calH (Probable).  Several additional tailoring enzymes within the cluster could be involved in the modification of the decalin polyketide product.  Those include the 3 cytochrome P450 monooxygenases CalE, CalG and CalL, of which one might be responsible for the introduction of the extra hydroxyl group attached to the backbone of the decalin moiety, at position C9 in the backbone, that allows for attachment of the linear moiety (Probable).  One tailoring enzyme activity that is expected to be involved in biosynthesis of calbistrin is an acyltransferase for connecting the two polyketide synthase products, and which could be performed by the cluster acyltransferase calJ (Probable).  The enzyme responsible for the biosynthesis of the linear moiety, probably a second PKS, has not been identified yet (Probable).
What are the official names of this protein?
Oxidoreductase calM, Calbistrin biosynthesis cluster protein N.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: IRX5_MOUSE
Sequence: MSYPQGYLYQPSASLALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAAAAAFSYVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEENIDLEKNDEDEPQKPEDKGDLEGPESGGAEQKATAGCERLQGPLSPAGKETEGSLSDSDFKESSSEGRHDELPRPPRAGESSPAGPATARLAEDAGPHYPASVPAPGPHPSAGELPPGSGGSSVIHSPPPPPPPPPAVLAKPKLWSLAEIATSSDKVKDGGGGSEGSPCPPCPGPMGGQTLGGSRASPAPAPARSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPSPTAGPGSHFNGLNQTVLNRADVLAKDPKMLRSQSQLDLCKDSPYELKKGMSDI
What is the function of this protein?
Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene.  Required for retinal cone bipolar cell differentiation.  May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina.  Involved in craniofacial and gonadal development (By similarity).  Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12.
What are the official names of this protein?
Iroquois-class homeodomain protein IRX-5, Homeodomain protein IRXB2, Iroquois homeobox protein 5.
What is the protein family that this protein belongs to?
Belongs to the TALE/IRO homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOLB_BARHE
Sequence: MMIMTTRTFFSWFIVICAFWLTSFSSVPVHAQLKGTISTADFNPIPIAVTDFFSNDSIGLKIAAVVAADLERSGLFLPLDKASFLEKISNPNRQPHFPYWQEIKAQGLVIGQVIRENDGRLRVDFRLWDVFGQRQLKGRRFYTATERWRRVAHMIADEIYSEMTGESGYFDTRIVFIDETGPQNARIKRLAIMDQDGANLIYISDGSELVLTPRFSPKRQEITYMAYEHNQVPHVYLQQIEMGQRELIGTFNNMTIAPRFSSDGQKVIMSLLQNDGSANLYTMDLRTRMMTRLTTTSAIDTSASYSPDGTKIVFSSDRSGKPQIYTMNADGSNLQRISSNEGSYSTPIWSPRGDYIAFTKQLEGQFSIGVMHPDGQGERILTTGFHNEGPTWAPNGRVLMFFRKNPGMGPKIYTIDITGRNERQLPTPNDASDPAWSPLLNIQ
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYP_GEOSW
Sequence: MRQSQSFIPTLREVPADAEVKSHQLLLRAGFIRQSASGVYTFLPLGQRVLQKVEAIIREEMNRAGAIELLMPALQPAELWQQSGRWYSYGPELMRLKDRHERDFALGPTHEEIITALVRDEVKTYKRLPLTLYQIQVKFRDEKRPRFGLLRGREFIMKDAYSFHTSQESLDETYNKMYEAYSNIFRRCGLNFRAVIADSGAIGGKDTHEFMVLSEIGEDTIAYSDASDYAANIEMAPVITTYEKSDEPLRKLEKVHTPGQKTIEEVASYLQVTPEKCIKSLLFKVDDRYVLVLVRGDHEANDVKVKNLFDASVVELATPEETKQAMNCEVGSLGPIGVSESVTIVADHAVKAIVNGVCGANEEGYHYIGVNPERDFTISEYADLRFIQEGDPSPDGKGTIRFARGIEVGHVFKLGTRYSKAMNATYLDENGRSQTMIMGCYGIGVSRLVAAIAEQFADENGLVWPASVAPFHVHLISVNAKNEEQRQLADEWYEKLGQAGFEVLYDDRPERAGVKFADSDLIGIPIRVTVGKRANEGIVEIKVRQTGESMEVSVDELIDTIRRLLQQ
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIUX_AGRIP
Sequence: MVRATCLLASCVLFALLLIVPASAYPRYPSNYFREEGQYEPEEIMDMLNRLGNLIQMERKMENYKEDITSEKRALDLGLSRGYSGALQAKHLMGLAAANYAGGPGRRRRDAH
What is the function of this protein?
Regulation of fluid secretion.  Stimulates Malpighian tubule fluid secretion.
What are the official names of this protein?
Diuretic hormone class 2, DH(31), Diuretic peptide, DP.
What is the protein family that this protein belongs to?
Belongs to the diuretic hormone class 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HTPX_STUS1
Sequence: MMRIFLFLATNLAVLVIASITLKLLGVDRYTGQNYGSLLVFCAVFGFAGSLISLFISKWMAKMSTRTEIISQPRTRHEQWLLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNRNDALVAVSQGLLERFSPDEVRAVLAHEIGHVANGDMVTLALIQGVVNTFVMFFARIFGNFVDKAILKNEDGHGIGYFVATIFAELVLGILASIIVMWFSRKREYRADEAGAQLAGTSAMIGALQRLRAEQGLPVHMPDSLKAFGINGSLKHGMAGLFMTHPSLEDRIEALRQRG
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
Protein: CFA45_PIG
Sequence: MPLSPAGVLSSTSTASNRSRNRPRYRTKALSSEVDESLFGGIKPLNQSDSPIVLLRDKHAIRKTLTALGLDHKPETIQLITRDMVRELIIPTKDPSGESLIMSPEEFERIRWASHVPTREELEAKEQACKKEKEAIVDAVTTRKKIMKQKEMVSRNNQKLSDLEEVAKERAQNLLQRASQLRMEQEEELKDMKKIILNAKCHAIRDAQILEKQLIQKELDAEEKRLDQMMEVERQKSIQRQEELDKKRREERIRGRRHIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLRDLERRHQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEISRLRALQEKVQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKMETEAQLRKSRLEQVAFKEHSLAVQVQRDRDEFERILRAQREQIEKEQQEEEKKAMERLQHANELRRQVRENQQKQVQDRIAIFEEGQRLKEEAQKRRERIEGIKKKKIEELRATGLPEKYCIEAERKANIPTNTSVN
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity).  It is an AMP-binding protein that may facilitate dynein ATPase-dependent ciliary and flagellar beating via adenine nucleotide homeostasis.  May function as a donor of AMP to AK8 and hence promote ADP production (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 45.
What is the protein family that this protein belongs to?
Belongs to the CFAP45 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Located in the proximal region of respiratory cilia.
Protein: RADA_METM6
Sequence: MADVLTELPGVGPSTAEKLIEAGYLDFMKIATSTIGELTDIEGISEKAAAKMIMAARDLCDLGFKSGVELLRQRQSVWRLSTGSKELDTVLAGGLESQSVTEFAGMYGSGKTQIMHQSCVNLQIAGKIYADLEGVVEEELENPKAVYIDTEGTFRPERVVQMAEGLGIDGQLVLDNTFVARAYNSDMQMLFAEKIEDLIKSGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMATLNKLADLYNCIVLVTNQVAAKPDAFFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKLYDSPHLPDSEAVFRITEKGIMD
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: DCUP_XYLFM
Sequence: MLKNDRLLRALRRDTVDRTPIWLMRQAGRYLPEYRAARQHAGSFLKMAKTPELACEITLQPLRRFPLDAAILFSDILMIPDAMGLELHFIEGEGPRLGKPIRDAAAITQLAVPDMETELRYVMDAVRLIRKELDNSVPLIGFSGSPWTLACYMIEGGGSKEYAHIKAMAFNAPDVLHQLLNTVTDAVISYLAAQRAAGAQALQVFDTWGGILSPTMYRTFSLPYLTRIARELERGTGTEHTPLVLFGKGNGPYIAELAMSGTEAVGVDWTIELEDAARRSNGQVALQGNLDPATLYGTPNNIAREVQRTLDSYAAGNGGSREGHVFNLGHGMTPGMDPDHVSALVEAVQRLSRR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT2_ECHTE
Sequence: MNAPLAGIWPWLPLLWAWLVPEVSSSWWYMRATGTSRVMCDNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCDTLDRDHSLFGRLLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTAKDSRGTFDWGGCSDNIDYGVKFARAFVDAKEKKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSPGTAGRVCNLTSRGMDSCEVMCCGRGYDTSRVTRMTKCECKFHWCCAVRCQDCLEALDVHTCKAPKSADWAVPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: NIKR_RHOP2
Sequence: MHRVTVTLDDDLMKKLDAIIEARGYQNRSEAIRDLARIGIQQTSAHASAEHCVGAMVYTYDHSKRDLPRKLTQSFHNHHELSRATMHVHLDHDQCLEVTILDGKANEIQHFADHIFSERGVRYGRLVTIPTSGDGHAHD
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: MURC_GEOUR
Sequence: MYGKIEKIHFVGIGGIGMSGIAEVLLNLGYKVSGSDLRKTEITERLEGLGGEIFIGHARENVANVDVVVISSAVHDDNPEVVEAMERLIPVIPRAEMLAELMRMKYGIAIAGTHGKTTTTSMVATILAKGGIDPTIVIGGRLNSIGTNARLGQGQFLVAEADESDGSFLKLSPTIAVVTNIDADHLDFYKDIDEIKDTFVQFINKVPFYGLAVLCLDNGNIADIIPLVKKRFNTYGLSTQADFRATDVRHTGFTTSFVAHYKGTLLGEITFSMPGAHNVLNALATIAVAMELNIPFAEIQAGFKAFGGVGRRFQVKGEVRDIMVVDDYGHHPTEIRATLAAAKGGWDRRLVVAFQPHRYSRTKELFEEFVKAFYDADILILTDIYPAGEKPIEGITAESLAARIKRHGQKDVTYIADRNAVCDHLLGIVKPGDIVITLGAGNIWQVGETLVEKLKGDL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRBL_RHIRD
Sequence: MVVHPSPKLELAFVTIGFVLLASSPALAQQGQVLTTLENSVVTAAKGWETTVMNAARSLFWILAGIEVGIAAVWLAINAASLDSWFAELVKRIMFIGLFAFILDRGLEFAKAVVDSLYQIGAGGGSASPANIFDAGIRVATKMSEQAKFGLWEDNALAIAAVFAMVVVVVSFSLVAAIFVAVMVEMYVGLLAGMIMLGLGGSSYTKDFAVKYLVYAFSVGMKLMALVMIARIGSDILLGLAEAPTATSEQFITTLAIAGISVVVFVIAMYVPPILQGLVQGASVGGGMEAIRHGGQAASAALGAGFLTIGAANRGFAAASAARAGGASLAGAAMRGLEAGVGGAAGAVGSAAKDKAIGSPGAYAGSMLGLANAKLDQQSGRPGTPPPPPPINDKK
What are the official names of this protein?
Conjugal transfer protein TrbL.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS6E_METM6
Sequence: MAFKVVVSDTKSGKSYQFETESTALIGKKIGDEISGSVVELEGYKLKITGGSDKCGFAMRHDIHGAMKMRVLLKNGPGYNVKEKGLRRRKSLRGNTISKDVTLINTKVVEYGPAPLGGEPENTE
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: AP2A_DROPS
Sequence: MAPVRGDGMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQSRNPVHVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEWTSRIIHLLNDQHMGVVTAATSLIDALVKCNPDEYKGCVNLAVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDSRSAPLVQFKLLHSKYHLCSPMTRALLLSTYIKFINLFPEIRTNIQDVFRQHSNLRSADAELQQRASEYLQLSIVASTDVLATVLEEMPSFPERESSILAVLKKKKPGRVPENEIRESKSPAPTSGPGSVLQNNVHVNNSHSKLNNSNANTDLLGLSTPPANNVGSNSNSTLIDVLGDIYGSNNNSSAVYNTKKFLFKNNGVLFENEMLQIGVKSEFRQNLGRLGLFYGNKTQVPLSNFNPVLQWSAEETLKLNVQMKAVEPTLEAGAQIQQLLTAECIEDYADAPTIEISFRYNGTQQKFSIKLPLSVNKFFEPTEMNAESFFARWKNLSGEQQRSQKVFKAAQPLDLPGARNKLMGFGMQLLDSVDPNPDNMVCAGIIHTQSQQVGCLMRLEPNKQAQMFRLTVRASKETVTREICDLLADQF
What is the function of this protein?
Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  Alpha adaptin is a subunit of the plasma membrane adapter (By similarity).
What are the official names of this protein?
AP-2 complex subunit alpha, Alpha-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adapter complexes large subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane.
Protein: RECF_LACAC
Sequence: MYLDHLTVQNFRNLKKLDVDFDPNVNIFIGKNAQGKTNLLEAIYFLALTRSHRTSSDRDLIGFDGEYTNLAGHVQKSQVTLNLRVLITKKGKKVWINRIEQAKLSKYVGQLNAILFSPEDLELIKGAPSLRRRFMDQEFGQINAEYLYFASKYRQVLIQKNNYLKQLAKGKAKDQVFLDVLSDQLAGIAAELIYRRFKFLTYLSHYASDAYTHISLGSEKLSIAYHPSVSDITADDTTEEIYQKILNSFNRNKASEIRKGTTTSGPHRDDIEFKLDGKNAHLYASQGQQRSIALSIKLAEIQLVHQLTDEYPLLLLDDVMSELDHGRQSALLNYIHGKTQTFITTTDLEGISWDIIKKPRVYHIQSGTISLEKEN
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.