PharMolix/UniProtQA huggingface dataset:
Protein: FTSY_MYCMS
Sequence: MGFWAKLKEKLTKKTNQVEQDEPILDQQDQQDQQEEQEQIIEKEIEQIKENKIKKTKTSETKKQEKPIETLKEKKKREKQKEKDKKVEKAMLKSAFNFSKDIKKLSKKYKQADDEFFEELEDVLIQTDMGMKMVLKVSNLVRKKTKRDTSFENIKDALVESLYQAYTDNDWTNKKYRIDFKENRLNIFMLVGVNGTGKTTSLAKMANYYAELGYKVLIAAADTFRAGATQQLEEWIKTRLNNKVDLVKANKLNADPASVVFDAIKKAKEQNYDLLLIDTAGRLQNKVNLMAELEKMNKIIQQVEKSAPHEVLLVIDATTGQNGVIQAEEFSKVADVSGIILTKMDSTSKGGIGLAIKELLNIPIKMIGVGEKVDDLLAFDIDQYIVHLSSGFMQGDEVEK
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: GRPE_LYSSH
Sequence: MIMRRIQVTETTENKDLVQGDVQAETATEEVERSEVQEEIELSVEEQYEANVAELQAKLDDDEENRHLRLRADFDNMRRRQQLDGEAAEKYRAQSLLSDLLPVLDNFERALQVETTSEETASIIKGIEMVYRSLLEATVFEGLQVIKAEGEQFDPNIHQAVMQEQDSEKETGVVLRELQKGYILKDRVLRPTMVSVNE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHA2_STAHJ
Sequence: MSLVYLLGGLIVIMLIVLMTLFIKSLRRFAGYIALLAPILASGYFLAQIPNVLHGKFVEFKIPWMPAIDVNLDFRLDGLGLMFGLIISIIGVAVFFYATQYLSVNRDNLPRFFLYLLLFMFSMLGIVVSNNTILMYVFWELTSVSSFLLISYWYSNAESQLGAIQSFIITVLGGLALLTGFIMLYIITGTNTISELLTQSHSISEHALFIPMMIMLLIGAFTKSAQFPFHIWLPKAMAAPTPVSAYLHSATMVKAGIFLLFKFTPILGLSDSYIYIVTFVGLITMIFGSVTALRQYDLKGILAYSTISQLGMIMSMVGLGGGIAQHSSGPMAETYTLILFAGLFHLMNHAIFKCALFMGVGIIDHEAGTRDIRRLSGMRKFFPKMNLVMTLAALSMAGVPLLNGFLSKEMFFDSLVSAIELQQFGLTLTIIVVAIGVIASIFTFVYAVYMLKETYWGEFDEKKVPKKHIHEPWLFSLPAIILMVMIPIIFFIPNFFTEHLVLPALRNVTNLGSSVDAIAPHVSQWHGVNLPLIFSVIVIIVGLILALKVNWKAITHQVIKYASITNSYRNVYRGFERYSGQMIRGLMNNRLNHYNIITVLIFSILIAYGIFQVGLPKLHQIEVSEFGPLEVILGIMISVVGIALVFIRQRLTMVILNGIIGYSVALFFLLMRAPDLALTQLVVETITTILFIVSFSRLPNIARTTANMKKETIKIIVSFIMAGAVVTLIFIAQQGDGLESISKYYTNAYELTGGKNIVNAILGDFRALDTMFEGIVLIIAGLGIYTLLHYKDRRGQDERK
What are the official names of this protein?
Putative antiporter subunit mnhA2, Mrp complex subunit A2, Putative NADH-ubiquinone oxidoreductase subunit mnhA2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL3_STAA3
Sequence: MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: M1_I81A2
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALSGNGDPNNMDRAVKLYRKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASKARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: LIPR2_MOUSE
Sequence: MPMDVRGCLFPSVQMLLCWLVSLLLATVGGKEVCYGHLGCFSNDKPWAGMIQRPSKIFPWSPEDIDTRFLLYTNENPNNYQIISATDPATINASNFQLDRKTRFIIHGFIDKGEEGWLLDMCKKMFQVEKVNCICVDWKRGSRTEYTQASYNTRVVGAEIAFLVQVLSTEMGYSPENVHLIGHSLGSHVAGEAGRRLEGHVGRITGLDPAEPCFQGLPEEVRLDPSDAMFVDVIHTDSAPIIPYLGFGMSQKVGHLDFFPNGGKEMPGCQKNILSTIVDINGIWEGTRNFAACNHLRSYKYYASSILNPDGFLGYPCSSYEKFQHNDCFPCPEQGCPKMGHYADQFEGKTATVEQTFFLNTGDSGNFTRWRYKVSVTLSGAKKLSGYILVALYGCNGNSKQYEVFKGSLQPEARYIRDIDVDVNVGEIQKVKFLWNNKVINLFRPTMGASQITVQRGKDGKEFNFCSSNTVHEDVLQSLYPC
What is the function of this protein?
Lipase that primarily hydrolyzes triglycerides and galactosylglycerides (PubMed:21382969, PubMed:9813028).  In neonates, may play a major role in pancreatic digestion of dietary fats such as milk fat globules enriched in long-chain triglycerides (PubMed:9813028).  Hydrolyzes short-, medium- and long-chain fatty acyls in triglycerides without apparent positional specificity (PubMed:21382969).  Can completely deacylate triacylglycerols (By similarity).  When the liver matures and bile salt synthesis increases, likely functions mainly as a galactolipase and monoacylglycerol lipase.  Hydrolyzes monogalactosyldiglycerols (MGDG) and digalactosyldiacylglycerols (DGDG) present in a plant-based diet, releasing long-chain polyunsaturated fatty acids (By similarity).  Hydrolyzes medium- and long-chain fatty acyls in galactolipids (By similarity).  May act together with LIPF to hydrolyze partially digested triglycerides (By similarity).  Hydrolyzes long-chain monoglycerides with high efficiency (By similarity).  In cytotoxic T cells, contributes to perforin-dependent cell lysis, but is unlikely to mediate direct cytotoxicity (PubMed:2302735, PubMed:9813028, PubMed:19451396).  Also has low phospholipase activity (By similarity).  In neurons, required for the localization of the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) to neurite tips through acyl chain remodeling of membrane phospholipids (By similarity).  The resulting OPPC-rich lipid membrane domain recruits the t-SNARE protein STX4 by selectively interacting with the STX4 transmembrane domain and this promotes surface expression of the dopamine transporter SLC6A3/DAT at neurite tips by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane (By similarity).
What are the official names of this protein?
Pancreatic lipase-related protein 2, PL-RP2, Cytotoxic T lymphocyte lipase, Galactolipase, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Zymogen granule membrane; Peripheral membrane protein. Cell projection, neuron projection. Note=Localizes to neurite tips in neuronal cells.
Protein: PCCX_HALMT
Sequence: MTEDLLSGLSIPDDADSEEAAAIAAAVGAHLHDQTAAAVAAAADEEETWDEKRWQYAGRLDSVTGCARRVPSGAPTNAWAASGRTDRF
What is the function of this protein?
Part of the propionyl coenzyme A carboxylase (PCC) complex involved in propionate utilization and in the production of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation.  The complex catalyzes the carboxylation of propionyl-CoA to methylmalonyl-CoA.  PCC is also able to catalyze the carboxylation of acetyl-CoA.  PccX could be responsible for the interaction of the biotin carboxylase and carboxyltransferase subunits.
What are the official names of this protein?
Propionyl-CoA carboxylase, protein PccX subunit, PCC.
Protein: Y551_GLUDA
Sequence: MIRIFIDADACPVRDETYRVAQRHGLQTFVVSNRMIAIPSSPLIERIVVTQGMDVADDWIAEQVNAHDIVISADIPLAARCVARGACVLDPRGRILDEDAIGMALAMRNLMEDLRATGAITQGGRGFTRADRSTFLSALDTAVVRGRKRAAQAR
What are the official names of this protein?
UPF0178 protein GDI0551/Gdia_1457.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: GLMU_YERPA
Sequence: MSNSSMSVVILAAGKGTRMYSDLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYGHGGELLKKTLADPSLNWVLQAEQLGTGHAMQQAAPHFADDEDILMLYGDVPLISVDTLQRLLAAKPEGGIGLLTVKLDNPSGYGRIVRENGDVVGIVEHKDASDAQREINEINTGILVANGRDLKRWLSLLDNNNAQGEFYITDIIALAHADGKKIATVHPTRLSEVEGVNNRLQLSALERVFQTEQAEKLLLAGVMLLDPSRFDLRGELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGDDSEISPYTVLEDARLDANCTVGPFARLRPGAELAEGAHVGNFVEIKKARLGKGSKAGHLSYLGDAEIGAGVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVANGATIGAGTTVTRDVAENELVISRVKQVHIQGWKRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMBP1_CAVPO
Sequence: MKLLLLLALLLGAVSTRHLKVDTSSLQSLRGEESLAQDGETAEGATREATAGALMPLPEEEEMEGASGSEDDPEEEEEEEEEVEFSSELDVSPEDIQCPKEEDTVKFFSRPGYKTRGYVMVGSARTFNEAQWVCQRCYRGNLASIHSFAFNYQVQCTSAGLNVAQVWIGGQLRGKGRCRRFVWVDRTVWNFAYWARGQPWGGRQRGRCVTLCARGGHWRRSHCGKRRPFVCTY
What is the function of this protein?
MBP may play some important roles in the allergic reactions and inflammations, since MBP is capable of releasing histamine from mast cells and damaging the epithelial cells of bronchial tubes.  Antiparasitic and antibiotic.
What are the official names of this protein?
Eosinophil granule major basic protein 1, MBP-1.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule (crystalloid core).
Protein: METK_DESRM
Sequence: MSRKLFTSESVTEGHPDKVADQISDAILDSILAKDPMARVACETFVTTGLVLVGGEISCQCYVDIPKVVRETILEIGYTRAKYGFDGDTCAVLTAIDEQSPDIAMGVDKALEAKTGETTEAEIEAIGAGDQGMMFGYATDETPELMPLPISLAHTMARRLSEVRKTGIVDYLRPDGKTQVTVEYDGDKPSRIDTVVISTQHHPEVDLETIRKDMIEKVALHVLPAELVDDKTRFLINPTGRFVIGGPHGDAGLTGRKIIVDTYGGSARHGGGAFSGKDPTKVDRSAAYAARYVAKNVVAAGLAKRCEVQLAYAIGVAHPVSVRVQTFGTGAVSDEVIIDLINRHFDLRPAGIIKSLELRRPIYKQTAAYGHFGRPDLDLPWECTDKADALRAEAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_METPE
Sequence: MAKKKQIGRRVEGWKAKSWYKVYVPEAFGSTPIGETIAADSANLVGRVMSTTLGEIAQDFAKQHIKMKFKISRVAGDAAYTEFIGHELTKDYLRSLVKRRTSRIDSHIMGSTKDGKRIHLTVTCYTLIGANSSQIHAIRNVISAQMATFVAQNDWATVVDGIVTGSISRDMLAQVKGIFPIRRIEVIKSKIESKVIIA
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: SYDP_TOLAT
Sequence: MADQVICALSDVFARWFAYQQQRGIQVCCPEDELRPSPCRYDAQHPERWKPWSRPEMSDLQNIASALECVFHPAIHAYYGHGYAGQITASFKGLAVTLVQPWNEEDFERLQQNLVAHVLMLRRLKLPITLFLATVSDESRVISLDNETGEVVLEQLGKKKRWVLADSLPAFLQRLSPLAQTAVTPAVPVNLPA
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: GPMA_METSB
Sequence: MDRLLVLVRHGQSEWNLQNLFTGWKDPDLTDLGVSEAKAAGRALKTAGVGFDIGFTSDLLRAQRTMKLLLAEFGQPDLQVTKNVSLNERDYGDLSGLNKAEAAQQWGDEQVHLWRRSYDVPPPGGESLKDTVARVLPYYCQEILPAVLNGKRTLVTAHGNSLRALIMVLDKLTPKTIPGMELATGVPIVYRLKADSTVESKQVLEP
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: CH10_ECO5E
Sequence: MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: HISZ_STRSV
Sequence: MNKITLPIGMHDKLFKRARVTYEIERDISDFLMAQGFNRIDTPTLEHFEVFSDYVEPHHYHLFDKKGELLVLRPDVTSQIGRVIASTRVHTPTKFSYSGKVFHYQEELRGLANELSQAGIEIIGYPARKAVLEAIKTAKQSLDLAQVKSYQFEFSHAAILQTILESLALDSQEEAQLLDYIRKKNRTGLFEFTQTRSSEFDDFLQELPYLFGPSQQVLARARELVDNERILTALDDIEQVLQSLSGLLDQTTMDLGQVAAMPYYTGLTFKVFGDRVPDAFLSGGRYDQLFKRFGAAELTAIGWSLDIDSVYQAIHDDLPDEGGKEGDGR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_THIDA
Sequence: MSEFTHFDESGRAIMVDVAGKDDTRRVATARGAIHMLPDTLGRILGGQAAKGDVLAVARIAAIQATKRTADLIPLCHPIALTRVVVDFAPETEVSRIVCTVTAETVGKTGVEMEALTGVSVALLTIYDMCKAVDRGMQIGDIQLVEKQGGRSGHWRLPD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CISY_BARQU
Sequence: MSENKAHITVNNKKIELSVRKGTLGPGVIEIASLYKETDTFTYDPGFTSTASCESKITYIDGDKGILLYCGYPIDQLAEKGDFLESCYLLLYGELPTKQEKIDFDRCIMQHMMVHEQFTRFFHGFRRDSHPMAVMVACLGAMSAFYHDSIDIKDAQQRMIAAIRLISKVPTLAAMAYKYSIGQAFVYPRNDLSYAANFLHMCFSVPCEEYKINPVLSRAMDRIFTLHADHEQNASTSTVRLVGSSGANPFACIAAGVACLWGPAHGGANEACLKMLQKIGSVERIPEFIARAKDKNDPFRLMGFGHRVYKNYDPRAKIMQQTCHEVLKELNIQDDPLLDIAIALENTALNDEYFIEKKLYPNVDFYSGITLKALGFPTEMFTVLFALARSIGWVAQWKEMIEDPAQKIGRPRQLYTGYAAREYVSIDKRISKNKMTTQ
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: LEU3_RHORT
Sequence: MPVSKKILFLAGDGIGPEVMAQVRRVMDWLNQTGRTAFEVEDALVGGAAYDAQGTPLHDDTVALALAADAVLLGAVGGPKWDASLPFELKPERGLLRLRKDLELFANLRPAMVFDALAEASTLKTELVSGLDVMIVRELTGGVYFGQPRGISALPNGERRGVNTQVYDTHEIVRVAKVAFDLAGKRGKRLCSVEKANVMESGLLWREEVTKLGADYPEIALSHMYADNCAMQLVRQPKQFDVIVTDNLFGDILSDCAAMLTGSLGMLPSASLGAADAAGNRRAMYEPVHGSAPDIAGQDKANPLATILSFSMMLRYSFDLAEEADLVDNAVRGVLAKGLRTGDIFQPGKTLVGTTGMGDALLAEMAQLAN
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUUP_ECOLI
Sequence: MAINSPLNIAAQPGKTRLRKSLKLWQVVMMGLAYLTPMTVFDTFGIVSGISDGHVPASYLLALAGVLFTAISYGKLVRQFPEAGSAYTYAQKSINPHVGFMVGWSSLLDYLFLPMINVLLAKIYLSALFPEVPPWVWVVTFVAILTAANLKSVNLVANFNTLFVLVQISIMVVFIFLVVQGLHKGEGVGTVWSLQPFISENAHLIPIITGATIVCFSFLGFDAVTTLSEETPDAARVIPKAIFLTAVYGGVIFIAASFFMQLFFPDISRFKDPDAALPEIALYVGGKLFQSIFLCTTFVNTLASGLASHASVSRLLYVMGRDNVFPERVFGYVHPKWRTPALNVIMVGIVALSALFFDLVTATALINFGALVAFTFVNLSVFNHFWRRKGMNKSWKDHFHYLLMPLVGALTVGVLWVNLESTSLTLGLVWASLGGAYLWYLIRRYRKVPLYDGDRTPVSET
What is the function of this protein?
Involved in the uptake of putrescine (PubMed:15590624, PubMed:19181795, PubMed:27803167, PubMed:23719730).  Imports putrescine for its utilization as an energy source in the absence of glucose (PubMed:23719730).
What are the official names of this protein?
Putrescine importer PuuP.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MINC_HELPY
Sequence: MLKTNQKNVHAFEIEKQEPEAVIGFLEKNHALLQYFLIIFKYDIESEVKAVLRKHQLLFLETNRVLNGRHIKTMPLKDETDHPKPNHSKTEPKTTIYERHIRSGEEIYSTNHLIFLGNIHNGAKIISEGCVSVYGVCEGAIVCFGECLILKEVKSAQIVFQNKILSLKEVEPLLVNKNIKIITKNDDILDIKEVL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization (By similarity).
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: SLA1_VANPO
Sequence: MTVFIGIYKAIYNYEPQTPDELTIQEDDLLYLLEKSNVDDWWTVKKRVIGSDIDEPAGLVPSNYVEVADVISQVKAVYDYHEVQNPDEELVFNENDTFDVYDDKDPDWILARSISTNQFGFIPGNYVEPLNAETGSAVPPSQPAAAAALPPPIATSATSPPAPALTAIDISTLPPPPQHSSKTNAQASDSGNRDYADKDLPDLPPNKPSRSNTETNEDDYYDAPPTKPARPNSTSNEQDTRQKARSRTSYYDQHYEDDAEDYRSSQRDDDYNDSEPSGELRTWNVAEIEGRKKRKAKLSIGNNRLFFSPQKGSPQDWSVDKLISYDNEKKHLFLEFVDPYKSLELHTGDNDTCKEILSVIGEIKGASRDPGFKEVEMASKSKKKGNVLYDFTAESNDELTIKQGQVVYIINDQKSKDWWLCELIDSGKRGVVPSHFIEPIQEKLTSSHTGGLFKSIKKFAKGGKSSKASDDAYSGSWEDDGMEGSTERRSRSGSYSTRKRASSTTSKKELPNPKKSRIWEDRSGTFKVEAQFIGCKEGKVHLHKANGVKIAVAAEKLSDDDLVYVERVTGFSLDKYKVRGSGTSSSRQDPRESERERRRRLRENDEKDRDRRLRERELNELQKARQLLDNERTKLQEQNEQPPSKPPRPSSGMGNRSRSQSTKDNYDWFEFFLNSGVDVSSCQRYTSNFEKERITEDMMVDINDSILRTLGLREGDIVRVMKYLDKKLGRDVSPQTAVVAGGMFSEADGSLKNNNSENQSSVGQQLLPNNPDLVSNTPIDDDTWTVRPAAKSEATLAPKTAEFTGSMQDLLDLKPLEPKKTEQLPIANLAVTESVVPEPNLKNLEPVRTGNVVQKPLANTLTGGATLVPLDPFKTGGNNVLPVTTGFVMMPFATGGAMPIQRTGGIIVPQTTFGTNAAGGIMPAQITGGLIPVATTGGLMPQTSFGVTPVANVVPLQRTGGAVMPIATTGGANILPQTTFNLPPSGTVLPIQRTANGLMAANTTGGMMPLNTTGGMMPLNTTGGMIPLNTTGGMMPMNTTGGVMSLQRTGGMMPQTSFGTQQMTGGAMNMMPQISFGAQQMTGGAMNVFPQTSFGAQQMTGGAMQNPNMGTMQNPNMGVMQNPNMGAFQPKSQFGMTLQRTGGAMAQPIMDAGVTGIAQGVQNMSMAQPLQNQPTGFGFGNGPQQPVQANIYNASASNPFGF
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein SLA1.
What is the protein family that this protein belongs to?
Belongs to the SLA1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: RL4_RHOPS
Sequence: MELKVTTLEGKEAGSVQLSDAIFGLEPRQDIVQRCVIWQLAKRQAGTHKAKGRAEIWRTGKKMYKQKGTGGARHGSQRVPQFRGGGRAFGPVVRSHAIDLPKKVRALALRHALSAKAKGGGLIVIDKAELEAAKTKALVGAFSGLGLTNALIIDGAEVNNGFATAARNIPNIDVLPVQGINVYDIVRRRKLVLTKAALDALEARFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PAXB_DICDI
Sequence: MATKGLNMDDLDLLLADLGRPKSSIKVTATVQTTATPSSGKNFDNSDIQNEIQSIIEELDQQPQTVQTISTPAPKNHNTTTTTASFSVSSQPAPQPPQQSQQIDGLDDLDELMESLNTSISTALKAVPTTPEEHITHANSNSPPPSLHKNTSSTNSASSLSRPNNNPSVVSTPQPGKVTSTATITTKKQPALSKATLETTSGNNVYSSQPSQSQPQPYKVTATNSQPSSDDLDELLKGLSPSTTTTTTVPPPVQRDQHQHHHQHQHHHHHNPNHNQTQTVTTQINIGRTNTPNNNNNNNTNSPKVVHGDDLDNLLNNLTSQVKDIDSTGPTSRGTCGGCRKPIFGETIQAMGKFYHPEHFCCHNCQNPLGTKNYYEQESLPHCEKCYQELFCARCAHCDEPISDRCITALGKKWHVHHFVCTQCLKPFEGGNFFERDGRPYCEADFYSTFAVRCGGCNSPIRGECINALGTQWHPEHFVCQYCQKSFTNGQFFEFGGKPYCDVHYHQQAGSVCSGCGKAVSGRCVDALDKKWHPEHFVCAFCMNPLAGGSYTANNGKPYCKGCHNKLFA
What is the function of this protein?
Required for cell-substrate adhesion, cell sorting, slug migration, and cell differentiation.  May function upstream of limB.
What are the official names of this protein?
Paxillin-B.
What is the protein family that this protein belongs to?
Belongs to the paxillin family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, filopodium. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Note=Expressed at the tips of filopodial structures located at the trailing ends of cells. Found in the focal adhesions at the cell-substrate interface.
Protein: Y189_ATV
Sequence: MKVLSFLIRQDHLLYLDIFAKQNNLTRSDAIRYAISVLDEESTPVSLVGFPGIKLVRTSVKLAENVISRIDRLAILSKITRSDVIRNAIYHLLINNAPKQLPPVTAQTEKKYGYVCPYCVSRFPTVRALKIHLKRRHNGFPWCPVCYKPLKNKNATNHFRRFTDPQHQFWYMISRKRYLSSHRKEAVKQ
What are the official names of this protein?
Putative zinc finger protein ORF189.
Protein: LIH1_YEAST
Sequence: MPVVHCSSNLPITPYIYERLVYFIKASSISSCISDNLLLVNKTFNDGGCPPHINFCNDEIINPTAGQTVVELVLNAKKGELGSGYLAVDHGKKVVILAFRGSTTRQDWFSDFEIYPVNYSPLCVKEYRKLIEEGKIRECEGCKMHRGFLRFTETLGMDVFKKMESILESFPEYRIVVTGHSLGAALASLAGIELKIRGFDPLVLTFATPKIFNSEMKQWVDELFETDAIEKESILKDEIQFRKGYFRVVHTGDYIPMVPPFYHPAGLEMFINKVGLPQNAEDIEYRGKNNRLTLKDGFREGMSGLVEDWLHVYEHRAYFIDVVGCSGL
What is the function of this protein?
Lipases catalyze the hydrolysis of the ester bond of tri-, di- and monoglycerides of long-chain fatty acids into fatty acids and glycerol.
What are the official names of this protein?
Putative lipase LIH1, Lipase homolog 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.