PharMolix/UniProtQA huggingface dataset:
Protein: POA1_ASPOR
Sequence: MASKATQGSIKEIQGDLFDAPDGAALIHACNCIGSWGGGIAKAFKQKYPAAYNIYHSHCQKYKFSPEYLVTSDPPNQPNNAQSSTRNKEIQLPEGTALIIPPQEKDYKDKDKKHWIICLFTSRNYGKRVSPPDVIIRNTELAVADMVRQIHRLRAEESGIGELWSCRFNSGLFGVEWVLSKRVLEESGLDFVVVRPVDEDE
What is the function of this protein?
Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.
What are the official names of this protein?
ADP-ribose 1''-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the POA1 family.
Protein: DXR_PELPD
Sequence: MKQLSILGSTGSIGVSTLEIVAAHPDRFRVSALTAGKNLELLARQIRQFSPRIAAVAAKEDVPRLAQLCDGLEVKIVGGVEGLIEAATADETDMVVAAIVGAAGLVPTAAAIRAGKDIALANKETLVTAGHLFMEMVSSHGVKLYPVDSEHSAIFQSLEGHRSDDISKIILTASGGPFLNTSLEQLAGVTVGDALNHPNWSMGRKITIDSATMMNKGLEVIEARWLFDAPMEKIHINIHPQSIIHSMVEYIDGCVIAQLGMPDMKAPIAYALSYPERVATGIKPLDLTTLTGLTFFKPDLEKFRCLGLAYRAMADGESMPAVMNAANEIAVDAFLEGRIAFLQIARVIEETMDSHIPHDLKSIAEVLQADQWGRDTARDICRRLSN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ATG18_CAEEL
Sequence: MSATTSEENPDSINYIGFNQDSKVICVGHKDGYMFYKTADILENNTLTYEGENLTHLGLNNCLIIERLFSSALMVVISQKDPRVLHVYHFTSRNIICDHRFNKSVLTVRLNRDRIVVCLEDCIYIYNLKDMKMMHNIMDTPTNKLGVLDLTSNPGNALIAYPGSTDTGSVHLFDAINLSSVSTFNAHEGTIACLKFNQEGNMIATASTKGTVIRVYSVPNGHRLFEFRRGVTRCVNIYSLCFSSDSKYLTSSSNTETVHVFKLEKTEGVDNKPEASTEGGGWFDAINKTFSAYMPSQVLQVGELMTTERSFATAKLPGAARSNQVSLVSHKNQQYVMAATSDGFVYAYRLDPEGGELDLIKQHNIGPKSDTSRASPTSTGSGGAAKSAEASNQSVPNMDDPDDFPPMSHTSG
What is the function of this protein?
Component of the autophagy machinery that is recruited to phosphatidylinositols on preautophagosomal structures, which are early autophagic structures, to promote autophagosome formation, and the subsequent degradation and clearance of engulfed apoptotic cells and P-granules in somatic cells (PubMed:12958363, PubMed:19167332, PubMed:21183797, PubMed:21802374, PubMed:22451698, PubMed:25124690, PubMed:28557996).  In particular, binds with high affinity to phosphatidylinositols including phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 5-phosphate (PtdIns(5)P), and more weakly to phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:21802374, PubMed:22451698).  Plays a role in mitophagy, which is the autophagic consumption of mitochondria, in response to dietary restriction (PubMed:30133321).  Involved in xenophagy, the autophagy-mediated degradation of pathogens and pathogen products, such as toxins (PubMed:27875098).  Also plays a role in membrane-pore repair (PubMed:27875098).  In a daf-18/PTEN- and daf-16/FOXO-dependent manner, required for the proliferation of germ stem cell progenitors in the gonad during the late phases of larval development (PubMed:28285998).  By regulating the release of neurotransmitters and neuropeptides, involved in the control of lifespan in response to dietary restriction and daf-2 signaling (PubMed:28557996).  Probably through its involvement in autophagy, required for dauer formation (PubMed:12958363).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, phagosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Partially localizes to the phagosome membrane of engulfed apoptotic cells.
Protein: GLYA_BRASO
Sequence: MTASAKPVSSVDSFFSATLAEADPEIAAAIRGELGRQRHEIELIASENIVSRAVLEAQGSVMTNKYAEGYPGARYYGGCEWVDVAENLAIDRAKKLFGANFANVQPNSGSQMNQAVFLALLQPGDTFMGLDLAAGGHLTHGSPVNMSGKWFKAAHYTVRRDDHLIDMDAVAKQAEEVKPKLIIAGGSAYSRPWDFKRFREIADSVGAYLLVDMAHFAGLVAGGVHASPVPYAHITTTTTHKSLRGPRGGLMLWNDEQFTKKFNSAIFPGLQGGPLMHVIAAKAVAFAEALRPEFKAYAKNVVENAKALAESLRAQGFDIVSGGTDNHLMLVDLRPKGLKGNVSEKALVRAAITCNKNGIPFDPEKPFVTSGLRLGTPAATTRGFGVAEFQQVGSLIAEVLNAIAQGPDGSAPLVEAAVKEKVKALTDRFPIYQ
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLAB4_NATMM
Sequence: MFVNETTDDRGQVGIGTLIVFIAMVLVAAIAAGVLINTAGMLQSQAEATGEESTDLVSERIDSTTAVGIVSETEVSEEAGADRGELEEIRLGVSGAAGSDNIDLSETIIQVVGPQGQDNLVMADPGDDEIDANDDGFVTVTDEDGNVDGDSTDATDADPSHIASGHFAVENEDGNFVEESDAVLDNDNGELTIILNPKVAPFGSQISESDEELDLQDLDTEDAFGAGDESSLSIVSPSGATTEVELNAPDLFSEDGEAVRL
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
What are the official names of this protein?
Flagellin B4.
What is the protein family that this protein belongs to?
Belongs to the archaeal flagellin family.
What are the subcellular locations of this protein?
Archaeal flagellum.
Protein: CLAT_DROME
Sequence: MASNEASTSAAGSGPESAALFSKLRSFSIGSGPNSPQRVVSNLRGFLTHRLSNITPSDTGWKDSILSIPKKWLSTAESVDEFGFPDTLPKVPVPALDETMADYIRALEPITTPAQLERTKELIRQFSAPQGIGARLHQYLLDKREAEDNWAYYYWLNEMYMDIRIPLPINSNPGMVFPPRRFKTVHDVAHFAARLLDGILSHREMLDSGELPLERAASREKNQPLCMAQYYRLLGSCRRPGVKQDSQFLPSRERLNDEDRHVVVICRNQMYCVVLQASDRGKLSESEIASQILYVLSDAPCLPAKPVPVGLLTAEPRSTWARDREMLQEDERNQRNLELIETAQVVLCLDEPLAGNFNARGFTGATPTVHRAGDRDETNMAHEMIHGGGSEYNSGNRWFDKTMQLIICTDGTWGLCYEHSCSEGIAVVQLLEKIYKKIEEHPDEDNGLPQHHLPPPERLEWHVGPQLQLRFAQASKSVDKCIDDLDFYVYRYQSYGKTFIKSCQVSPDVYIQLALQLAHYKLYGRLVATYESASTRRFLHGRVDCIRAASTEALEWAKAMCQGEGANVPLESDREDEEESRKVKFSIYSKDHLRELFRCAVARQTEVMVKNILGNGIDIPLLGLREASIEVTGEMHELFKDESYIISQCFLLSTSQVACSTDSFMGYGPVTPRGYGCSYNPHPEQIVFCVSAFYSCEDTSASRYAKSLQDSLDIMRDLLQN
What is the function of this protein?
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
What are the official names of this protein?
Choline O-acetyltransferase, CHOACTase, Choline acetylase.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
Protein: F8H1_OCIBA
Sequence: MPFPMEVLQASSLSFPLLRRHSRNNLINKFRNPTLPRIDIPRQNIDLKTFAATTPTVACPPSDPEIIPEKKEDKFDWYENWYPVATVCDLDKRRPHGRKVIGIDVVVWWDRKENAWKVFDDTCPHRLAPLSEGRIDQWGRLQCVYHGWCFDGVGACKFIPQAPHDGPPVETSKKACVKGVYPSCVRNGIVWFWPNSDPKYKDIYLTNKPHYIPELDDPSFTCTTITREVPYGYEILAENLMDPSHVPYAHYGILELEKVKESSKRDREGGHEMEISVGTIDVNGFSAKHVSADYYFVPPYVYYGRITPNAATKTKDATLPVVPEEKTAMIVFYCIPVTPGYSRLIYAGARNFAVQIDRFVPRWITHMSHNLIFDSDLFLLHVEEQKLKDLDWHKSCYIPTKADGQVVAFRRWLNKYGGTQVDWRNNFTPALPPTPSREQLFDRYWSHTAECSSCSVACKRLNALEIGLQAMSLVFVAMAAAVSAPATRYSMVAMAVLSFLASKWLSHFIHKTFYNHGYDHAFV
What is the function of this protein?
Rieske-type, PAO-family oxygenase involved in the biosynthesis of polymethoxylated flavonoids natural products such as nevadensin and salvigenin, aroma compounds which contribute to the flavor of sweet basil, and exhibit pharmacological activities such as anti-allergic, anti-oxidant, antibacterial, anti-proliferative, and anti-inflammatory effects (PubMed:25139498).  Catalyzes the 8-hydroxylation of salvigenin (SALV) to produce 8-hydroxysalvigenin (8-OH-SALV) (PubMed:25139498).  Can also use cirsimaritin (CIRM) as substrate with low efficiency (PubMed:25139498).
What are the official names of this protein?
Flavonoid 8-hydroxylase 1, chloroplastic, ObF8H-1.
Protein: ATRF1_STAAM
Sequence: MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
What are the official names of this protein?
Putative acetyltransferase SAV0762.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: UBACT_YANXG
Sequence: MPQDQQRKKQFDPNPNRDDSQRKTPVDKEIDDIIDEADEIVKRNKEQAKKKQPSRQ
What is the function of this protein?
May function as a protein modifier covalently attached to lysine residues of substrate proteins.  This may serve to target the modified proteins for degradation by proteasomes.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein UBact.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-like protein UBact family.
Protein: RSMH_POLAQ
Sequence: MNITHRPVLLAEAVTALISGPLIQEKNAAKKIVVIDGTFGRGGHTQALLKSLEMSARVISFDKDLDAISVAQQIQDPRFTIVHDSFAHMDQYAQAESVDGILLDLGISSPQVDEAHRGFSFRREGPLDMRMNTDQGLTAAEWLEQAPQEEITRVIKTYGEERFAFQIAKAIVAKREEGLSPKTTTELASLVASVVRTREAGQDPATRTFQALRIFINRELEDLELGLKAALKLLKPGARLAVISFHSLEDRIVKQFFQAHAKVEIPRGLPVREKDLPQSALEIIGRVKPSDLEISENPRARSAIMRVAEKRMGAPV
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VES_ECOK1
Sequence: MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASITSIAANGEFSLFPGMERIVTLLEGGEMFLESADRFNHTLKPLQPFSFAADLVVKAKLTAGQMSMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFDGRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ
What are the official names of this protein?
Protein Ves.
What is the protein family that this protein belongs to?
Belongs to the Ves family.
Protein: SHUT_ADES1
Sequence: MAAEGERQNLLSKHLERQVKILQSICKNDSEACNLLDLGYILEKNLFAPADSRKADSGPDPQLNFFPPFLTPECLALHYPFFLTTSIPPSCKGNRSGTDTYSQFCSRSSCLEDIPDPSEWDDSLGNVSLMAELKENQKLAPLEEDSPRTTAVDESKCSSKQSYSYPALTFPPQVQKILFDYLIGESQDPNDLDSEYKLAFTDEDLPQEGQAEKTKQRETLGAVATFGAVLLSIQRLFTHPVVIKNTQESLHYTFLHGFVRMVHLLTEVNLSEFVTFHGLTHRNRLNNPVQHRQLEGADRFDYILDTIYLYLVFAWQTAMDIWSQTIDEETERNLRERVKSLKPELAGANYAEACSLVSNTVFPPLLREALVVNIPDFVNQTQLANFRLFINNKSNVPASVCPALPSDFIPLTYEESHPVLWAHVMLLRLAAFLLNHGQYVQAPDESSISLPLCDCNLCAPHRMPCYNPMLLNEILSIGKFEVRGPDTEGKGFSLTPQVFANAYMEKFYSEDFHPHQVVLYKDDKAQFKTEPTAAVIREPKLLALIRESQTRREKSILKRGGGRYLDPQTGEVLGESSHGIGEELQDGPSYGEKPSHDLPSYGKQNPVAGRGLQAAGERVRRDAGSPSQPTEQLGRRTPQRGGTGRDKRGRGRGGRSATPDPRQETAEKESLQGTRRESS
What is the function of this protein?
Protein that inhibits host translation while promoting late viral translation by ribosome shunting.  Blocks host cap-dependent translation by binding to eIF4G, displacing MKNK1 from cap initiation complexes and preventing EIF4E phosphorylation.  Binds to the tripartite leader sequence of viral late mRNAs and recruits host eIF4G, PABPC1/poly-A binding protein and 40S ribosomes subunits on viral mRNAs, allowing ribosome shunting and efficient translation of late viral mRNAs even though conventional translation via ribosome scanning from the cap has been shut off in the host cell.  During assembly, acts as a chaperone protein that helps hexon proteins assembly into trimers.
What are the official names of this protein?
Shutoff protein, 100 kDa protein, p100K, 100K-chaperone protein, L4-100K, Shutoff protein 100K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae shutoff protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: CLCA_SALNS
Sequence: MKTDTSTFLAQQIVRLRRRDQIRRLMQRDKTPLAILLMAAVVGTLTGLVGVAFEKAVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGCVGPVFNSLVLRTQDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPEAAGGGFNLIPIAAAGNFSVGLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQDAEQAAKNQNAPAGENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATF4_HUMAN
Sequence: MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSEWLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
What is the function of this protein?
(Microbial infection) Binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I.
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-4, cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, Tax-responsive enhancer element-binding protein 67, TaxREB67.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with GABBR1 in hippocampal neuron dendritic membranes (By similarity). Colocalizes with NEK6 at the centrosome (PubMed:20873783). Recruited to nuclear speckles following interaction with EP300/p300 (PubMed:16219772).
Protein: SCPL1_DICDI
Sequence: MMKLLFIIISIIFVINVSNSTPTLQLSGYFNVNETTNANLFYLFYESQNSPSTDPLILWLTGGPGCSSLMAAFYENGPYFVNDNLTLSENPNSWNMVANVLYVDSPLGAGFSYVVDSDGYSTTETEISENLYSFLTQFLSKYPKYSKLPLYIFGESYAGHYVPSFSYYIYQKNLGLATINLKGLAIGNGMVDPYIQYGSLGPFAYAHGMLDINALKETEGLYESCQQAIDSGDYNMTTQICNNIMDIVQEYAGNFNVYDVSKTCYPNEPLCYNFTAIIDYLNLASTKQSFGVLPNSTWNVCSTQPYSAIIRDWFNTPINYIPTLLENYKVLVYNGNYDWICNFLGSTEWTSQLKWKYNQEFNNSPRKILYINGNTISGYSQSYDNLTMQVLLGASHMAPREAPVAALAMVESFIQN
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase S10 family member 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y639_DICNV
Sequence: MKFPMNNKKMTTKKRGQYGELLAADYLTAHGLNIVAKNVYSRYGEIDLIAQDDRVLVFVEVRLRRAQALVSAAESITPEKLRRCYQSAQDYLQKNYAVPPDCRFDAVLITQYQTHHEIEWLKNVIF
What are the official names of this protein?
UPF0102 protein DNO_0639.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RUVA_HERA2
Sequence: MIASVRGVVQLIGQDQVVIDVHGVGLAIAVPRTVLATIGAIGDTAQLYTHLHVREDMLALFGFSSPAQRALFELLLGVSGIGPKVALALLSAATPEELQHAIAREDITMLSKVPGIGKKTAARLVLELKGKFGVATISPQLSTNPGLLALNTELIDILTSLGYSTTEAQAALNALPADAPADTEERLRLALQYFGGV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ACTB_DICDI
Sequence: MAETKVAPNLTGIEQTKAGQSFTEKLSAEAMEFFCNVAKLPFSQQAVHFLNAYWAEVSKEAEFIYSVGWETIKYADMHCKGIQLVFKYDEGNDLDFDIALYFYEQLCKFCEDPKNKNYATTYPISQPQMLTALKRKQELREKVDVNFDGRVSFLEYLLYQYKDFANPADFCTRSMNHDEHPEIKKARLALEEVNKRIRAYEEEKARLTEESKIPGVKGLGATNMLAQIDSGPLKEQLNFALISAEAAVRTASKKYGGAAYSGGAGDAGAGSSAGAIWWMNRDLEEKKKRYGPQKK
What is the function of this protein?
May contribute to the structure and reorganization of filopodia and pseudopodia accompanying cell movements.
What are the official names of this protein?
Calcium-regulated actin-bundling protein, 34 kDa actin-binding protein.
Protein: LC2B2_MORNI
Sequence: TQSTGTSQTVEVGLWGGPDN
What is the function of this protein?
Alpha-methyl-D-mannoside and D-mannose specific lectin.  Binds IgA.
What are the official names of this protein?
Agglutinin beta-2 chain isoform 2, Agglutinin II beta chain, isoform 2, MNA II beta, isoform 2.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: GREA_BARBK
Sequence: MEKVPMTTAGFETLKEELRWRQQQERPRIIEAISEARAHGDLSENAEYHAAKEAQSYNEGRINELEDYIARAEVIDVSRLSGNQIKFGATVKLLNEDTEEKKVYQIVGDQEADVKIGKISISSPIARALIGKEEGDVIEVNAPGGAHNYEIIKIQYI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ERA_PSEA8
Sequence: MTDMHDDIPAGSRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGEVQAVYVDTPGLHKSGEKALNRYMNRTASAALKDVDVVIFVVDRTRWTEEDQMVLERVQYVSCPVLIAVNKTDRIEEKADLLPHLEWLTQQLPKAEVVPISAQHGTNLDVLEKLVAERLPESEHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQEGRILHIHALILVEREGQKKIIIGDKGERIKSIGQNARKDMEVLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: NUP85_YEAST
Sequence: MTIDDSNRLLMDVDQFDFLDDGTAQLSNNKTDEEEQLYKRDPVSGAILVPMTVNDQPIEKNGDKMPLKFKLGPLSYQNMAFITAKDKYKLYPVRIPRLDTSKEFSAYVSGLFEIYRDLGDDRVFNVPTIGVVNSNFAKEHNATVNLAMEAILNELEVFIGRVKDQDGRVNRFYELEESLTVLNCLRTMYFILDGQDVEENRSEFIESLLNWINRSDGEPDEEYIEQVFSVKDSTAGKKVFETQYFWKLLNQLVLRGLLSQAIGCIERSDLLPYLSDTCAVSFDAVSDSIELLKQYPKDSSSTFREWKNLVLKLSQAFGSSATDISGELRDYIEDFLLVIGGNQRKILQYSRTWYESFCGFLLYYIPSLELSAEYLQMSLEANVVDITNDWEQPCVDIISGKIHSILPVMESLDSCTAAFTAMICEAKGLIENIFEGEKNSDDYSNEDNEMLEDLFSYRNGMASYMLNSFAFELCSLGDKELWPVAIGLIALSATGTRSAKKMVIAELLPHYPFVTNDDIEWMLSICVEWRLPEIAKEIYTTLGNQMLSAHNIIESIANFSRAGKYELVKSYSWLLFEASCMEGQKLDDPVLNAIVSKNSPAEDDVIIPQDILDCVVTNSMRQTLAPYAVLSQFYELRDREDWGQALRLLLLLIEFPYLPKHYLVLLVAKFLYPIFLLDDKKLMDEDSVATVIEVIETKWDDADEKSSNLYETIIEADKSLPSSMATLLKNLRKKLNFKLCQAFM
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  NUP85 is involved in nuclear poly(A)+ RNA and pre-ribosome export, in GSP1 nuclear import, in NPC assembly and distribution, as well as in nuclear envelope organization.
What are the official names of this protein?
Nucleoporin NUP85, Nuclear pore protein NUP85.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin Nup85 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
Protein: DC122_MOUSE
Sequence: MAPQQTGSRKRKASEVEQGAGTSSLPGRAAAAAGTGQADGPLLLAKRPRRPVARRSLVHYLKGRALGADGHPGVAGFEGDLRSYGVLRLPELLRERQLTLGPLNKVFASQWLNARQVVCGTKCNTLFVVDVQTGRITRIPLMRDRGPGQTRAQPTCGIHAIQLNPSKTLLATGGENPNSLAVYQLPTLDPVCLGDRQGHRDWIFAIAWMSDTVAVSGSRDGTVALWRVDSDMFNGSIPWHNNSGIPRYSHIRPRDMEAIPRATTNPGNRKVRALAFSGRNQELGAVSLDGYFHLWKARSSLSRLLSLRLPYCRENVCLTYCDELSLYAVGSQSHVSFLDPRQRQQNIKPLCSREGGTGVRSLSFYQHIITVGTGHGSLLFYDIRAQKFLEERASASPDSFLGRTGRKLKLTCGRGWLNQDELWVNYFGGTEEFPNALYTHCYNWPEMKLFVGGGPLPSGLHGNYAGLWS
What are the official names of this protein?
DDB1- and CUL4-associated factor 12-like protein 2, WD repeat-containing protein 40C.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF12 family.
Protein: RL14_CLAMS
Sequence: MIQQESRLKIADNTGAKEILTIRVLGGSGRRYAGLGDVIVATVKDAIPGGNVKKGEVVKAVIVRTKKETRRPDGSYIKFDENAAVILNSNGEPRGTRIFGPVGRELRDKKFMKIISLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SBT31_ARATH
Sequence: MIQTLKTDSSFRLCFAAIAFGFVFIMNGKLSSGTTPHEFPVYIFYLGERKHDDPNLVTQSHLEILKSVLGSEEATNKSMVYSYHHGFSGFAAKLKPAEAEKLKKHPEVIILLENRKLGLQTTRTWDYLGQFSTPTSSKSLLHETNMGSGAIIGVIDSGIWSESGSFDDDGYGPIPKHWKGQCVSADQFSPADCNKKLIGAKYYIDGLNADLETSINSTTEYLSPRDHNGHGTQVSSTAAGSFVSNMTLLGLSSGSIMRGGAPKAHIAMYKACWDVEGGMCSVADVWKAFDEAIHDGVDVLSVSVGGSALKTLDVEIDIAIPALHAVNKGIPVVSPAGNEGSRSSSVINVSPWILTVAATTLDRSFSTLITLENNKTYLGQSLYTGPEISFTDVICTGDHSNVDQITKGKVIMHFSMGPVRPLTPDVVQKNGGIGLIYVRNPGDSRVECPVNFPCIYLDMEVGSELYTYIQTRSSMKIKISPYKTIIGESVASKVAKSSARGPSSFSPAILKPDIAAPGLTLLTPRIPTDEDTREFVYSGTSMATPVIAGIVALLKISHPNWSPAVIKSALVTTAMKTDPYGERLTVDGGNYKVADAFDYGGGLVNLEKATDPGLVYDMDINDYTHYLCSQTLYTDKKVSALTGNVNNKCPSSSSSILDLNVPSITIPDLKGTVNVTRTVTNVGRVKSVYKPVIEAPFGFNVVVSPKKLKFNKTRNKLAFTVTVSPGSHRVNTAFYFGSLTWSDKVHNVTIPISLRTRFIDNFFL
What are the official names of this protein?
Subtilisin-like protease SBT3.1, Subtilase subfamily 3 member 1, AtSBT3.1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQGF_BUCCC
Sequence: MIILCFDYGIKIIGIAIAETKLNYSTPIKSIFNNKKKNFWNQINIIINMWKPKYIVIGYPYKIKKKINKKIKKFAKEIKKKFKINFFLCDENYSTTEALLFLKEKKKKKKYCLHSISAKIILDSWIRKNI
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_STRS7
Sequence: MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGMQDNLSGVENPVSVHVLNIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPDEDSLDQTHSVYVDQWDWEKVIPDGQRNLAYLKETVETIYKVIRLTELAVEARYDIEAVLPKKITFIHTEELVARYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDYDDWTSESENGYHGLNGDILVWNEQLGTAFELSSMGIRVDEEALKRQVDITGDQERLQFDWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVRDTYDNIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.