PharMolix/UniProtQA huggingface dataset:
Protein: LMO7_HUMAN
Sequence: MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDIILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNPGNAFDQFLPKCWTPEDVNWKRIKRETYKPWYKEFQGFSQFLLLQALQTYSDDILSSETHTKIDPTSGPRLITRRKNLSYAPGYRRDDLEMAALDPDLENDDFFVRKTGVFHANPYVLRAFEDFRKFSEQDDSVERDIILQCREGELVLPDLEKDDMIVRRIPAQKKEVPLSGAPDRYHPVPFPEPWTLPPEIQAKFLCVFERTCPSKEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVPPISFTPGPCSEADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKSGRPTAM
What are the official names of this protein?
LIM domain only protein 7, LMO-7, F-box only protein 20, LOMP.
Protein: TX31A_SCODE
Sequence: MKFSMAILLVMAPIMFSLDKCYSADDKCEDSLRREIACTKCRDRVRTDDYFYECCTSESTFKKCQTMLHQ
What is the function of this protein?
Toxin that acts on KCNE1 and to a lesser extent KCNE3, the auxiliary subunits of potassium channel Kv7. 1/KNCQ1 (PubMed:26307551).  The toxin reversibly inhibits the slow delayed rectifier potassium currents (IKs) exhibited by the complex KCNQ1-KCNE1 (IC(50)=652 nM) and by the complex KCNQ1-KCNE3 (30% inhibition at 1 uM) (PubMed:26307551).  The positively charged part of toxin binds to the negatively charged residues of the N-terminal amphipathic helix from the KCNE1 extracellular region (PubMed:26307551).
What are the official names of this protein?
Kappa-scoloptoxin(03)-Ssd1a, Kappa-SLPTX(03)-Ssd1a, Toxin SSD609.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-03 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GRPE_BORAP
Sequence: MEKKETKNETEKTNKQDNKNTKSQKKENLNLVNSDKKITELENEISNLKDLYLRKQAEFENFRKRLEKEKDNFVKFANETIMKDVVNFLDNLERAINSSKKSKDFDNLLTGISMIENEILSIFDKKYNLKKFGENGENFDPSRHEAISIEEKEDFKNPEIVEVYQKGYCYNDRILRTAKVKVAQSKN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2380_ALKCK
Sequence: MISPNRQGIVVWLTSLKYARQLRRFGHVQYVSKKMKYVVFYCDQSKVPELVDKLSSFHFVTDVKPSMRPFINTEYEGAKPDKAKEYDYKLGI
What are the official names of this protein?
UPF0298 protein ABC2380.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADRB2_CAVPO
Sequence: MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.
What are the official names of this protein?
Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Golgi apparatus. Note=Colocalizes with VHL at the cell membrane. Activated receptors are internalized into endosomes prior to their degradation in lysosomes. Activated receptors are also detected within the Golgi apparatus.
Protein: CSRN3_HUMAN
Sequence: MSGILKRKFEEVDGSSPCSSVRESDDEVSSSESADSGDSVNPSTSSHFTPSSILKREKRLRTKNVHFSCVTVYYFTRRQGFTSVPSQGGSTLGMSSRHNSVRQYTLGEFAREQERLHREMLREHLREEKLNSLKLKMTKNGTVESEEASTLTLDDISDDDIDLDNTEVDEYFFLQPLPTKKRRALLRASGVKKIDVEEKHELRAIRLSREDCGCDCRVFCDPDTCTCSLAGIKCQVDRMSFPCGCTKEGCSNTAGRIEFNPIRVRTHFLHTIMKLELEKNREQQIPTLNGCHSEISAHSSSMGPVAHSVEYSIADSFEIETEPQAAVLHLQSAEELDCQGEEEEEEEDGSSFCSGVTDSSTQSLAPSESDEEEEEEEEEEEEEDDDDDKGDGFVEGLGTHAEVVPLPSVLCYSDGTAVHESHAKNASFYANSSTLYYQIDSHIPGTPNQISENYSERDTVKNGTLSLVPYTMTPEQFVDYARQAEEAYGASHYPAANPSVIVCCSSSENDSGVPCNSLYPEHRSNHPQVEFHSYLKGPSQEGFVSALNGDSHISEHPAENSLSLAEKSILHEECIKSPVVETVPV
What is the function of this protein?
Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity.  Plays a role in apoptosis (By similarity).
What are the official names of this protein?
Cysteine/serine-rich nuclear protein 3, CSRNP-3, Protein FAM130A2, TGF-beta-induced apoptosis protein 2, TAIP-2.
What is the protein family that this protein belongs to?
Belongs to the AXUD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA_PROMP
Sequence: MLKLLLGDPNTRKLKRYQPMVEEINLLEEDVSILTDDELRNETHNLKSNISSELNIKKQKELLEETLPKAFAIVREASKRVLEMRHFDVQLIGGMVLHEGQIAEMKTGEGKTLVATLPCYLNALTGKGVHVVTVNDYLARRDAEWMGQVHRFLGLSVGLIQQDMSPAERKKNYACDITYATNSELGFDYLRDNMATEIEEVVQRKFNYCVIDEVDSILIDEARTPLIISGQIERPQEKYQKAAELSLSLIKAKELSKDGIDPEGDYEVDEKQRSCILTDQGFAKCEEALKVNDLYDPKDPWAHYITNALKAKELFVKDVNYIIKKDEAVIVDEFTGRVMPGRRWSDGQHQAIEAKEGLKIQPETQTLASITYQNFFLLYPGLAGMTGTAKTEEVEFEKTYKLESTVVPTNQIRKRQDWADQVFKTELGKWKAVANETAEIHRNGRPVLVGTTSVEKSELLSSLLFEQQIPHNLLNAKPENVEREAEIVAQAGRSGAVTIATNMAGRGTDIILGGNSDYMARLKLKETLMPLLVKPDNEHKPPIPQQRNSKSGGGFSANVDSIANKNTKSGVDSLFPCQLGEDIKRKLSLLSNELVKNWGDRSLTILELDDKIATAAEKAPTEDKLIQSLRESLSEVKNEYEKVLIHEEENVRNAGGLHVIGTERHESRRVDNQLRGRAGRQGDLGSTRFFLSLEDNLLRIFGGDRVANLMNAFRVDEDMPIESGMLTRSLESAQKKVETYYYDIRKQVFEYDEVMNNQRKAVYNERLRVLKGNDLKKQVIGYGERTMEEIVEAYINPDLPPEEWDIDQLISKVKEFIYLLNDLKSEDVSVLSIEELKNYLQEQLRIAYDLKEAQIEKFRPGLMREAERFFILQQIDNLWREHLQSMDSLRESVGLRGYGQKDPLIEYKNEGYDMFLEMMTNMRRNVIYSMFMFQPKSEKVTNN
What is the function of this protein?
Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: RAE1D_ARATH
Sequence: MAVAPARARSDYDYLIKLLLIGDSGVGKSCLLLRFSDDTFTTSFITTIGIDFKIRTVELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDESSFNNIRNWMKNIEQHASDNVNKILVGNKADMDESKRAVPTAKGQALADEYGIKFFETSAKTNLNVENVFMSIAKDIKQRLTETDTKAEPQGIKITKQDTAASSSTAEKSACCSYV
What is the function of this protein?
Involved in membrane trafficking from the Golgi to the plasma membrane.
What are the official names of this protein?
Ras-related protein RABE1d, AtRABE1d, Ras-related protein Rab8C, AtRab8C.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus membrane. Cell membrane; Lipid-anchor.
Protein: CH104_RHIME
Sequence: MASTDFRPLHDRVVVRRVESEEKTKGGVIIPDTAKEKPQEGEIVAVGSGARDESGKVVPLDVKAGDRILFGKWSGTEVKINGEDLLIMKEADIMGVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES 4, 10 kDa chaperonin 4, Chaperonin-10 4, Cpn10 4.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIRC2_MOUSE
Sequence: MARETDCDLDKKTSLTSDAEMRPEPPALCVNPGNPVFSCMLDPKTLHTATSLSKAQMIMYKTSASQYGAFSPRPFFFPCKFLPQEQAFTEHLKTTGFYQNNSLNVGPDRTRTIDSPNYQHTL
What is the function of this protein?
Microtubule inner protein involved in the attachment of outer dynein arms (ODAs) to dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Piercer of microtubule wall 2 protein.
What is the protein family that this protein belongs to?
Belongs to the PIERCE2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: PTR8_ARATH
Sequence: MEVEKTEKNIAEDDESKIIYRGWKVMPFIIGNETFEKLGIVGSSSNLVIYLTTVFNMKSITAAKVVNIYGGTSNFGTIVAAFLCDSYFGRYKTLSFAMIACFLGSVAMDLTAVIHPLHPAQCAKEIGSVCNGPSIGQIMFLAGAMVLLVIGAGGIRPCNLPFGADQFDPKTKEGKRGIESFFNWYFFTFTFAQMVSLTLIVYVQSNVSWSIGLAIPAILMLLGCIIFFAGSKLYVKVKASGSPIHSITRVIVVAIKKRRLKPVGPNELYNYIASDFKNSKLGHTEQFRFLDKSAIQTQDDKLNKDGSPVDAWKLCSMQQVEEVKCVIRVLPVWLSAALFYLAYIQQTTYTIFQSLQSDRRLGPGSFQIPAGSYTVFLMLGMTIFIPIYDRVLVPFLRKYTGRDGGITQLQRVGAGLFLCITSMMVSAIVEQYRRKVALTKPTLGLAPRKGAISSMSGMWLIPQLVLMGIADALAGVGQMEFYYKQFPENMRSFAGSLYYCGIGLASYLSTFLLSAVHDTTEGFSGGSWLPEDLNKGRLEYFYFLVAGMMTLNLAYFLLVSHWYRYKDVVAKDKDMDKTSAEFDKVSV
What is the function of this protein?
Low-affinity nitrate transporter facilitating nitrate loading into root phloem.  Not involved in dipeptides transport, but has a weak glucosinolate transport activity.
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 2.9, AtNPF2.9, Nitrate transporter 1.9.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROP_STAEQ
Sequence: MVDGNNAKKTVIATGIGNAMEWFDFGLYSYLAVIISKNFFSQVDNDQLKLVFTFATFAIAFLLRPIGGIVFGIIGDKYGRKIVLTTTIILMAFSTLLIGVLPTYNEIGVWAPILLLLARVLQGFSTGGEYAGAMVYVAESSPDRKRNSLGCGLEIGTLSGYIAASILVFALNISLTETQLNSWGWRIPFLLGMFLGLFGLYLRRKLEESPIYENEQRELQKHPTREPIGVFTLIRFYYKDIIVCFVAVAFFNVTNYMVTAYLPSYLEGVIKLNGTTTSIMITCIMVIMIPLALMFGRIADRIGEKKVFLIGLGGLILLSVVAFSLMQLQSLFFVSIGVLILGFFLSTYEATMPGSLPTMFYTHVRYRALAITFNVSVSLLGGTTPLIASYLVSTTNNPLTPAYYLTVISIIGFIVIALLHKSTASKSLKGSYPNVDNEKDREYYEKNPEQALWWLKERQEKEKF
What is the function of this protein?
May be a proton symporter involved in the uptake of osmolytes such as proline and glycine betaine.
What are the official names of this protein?
Putative proline/betaine transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYI_STAA3
Sequence: MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFDVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQTSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_PARPJ
Sequence: MSEIRKNDHRLMQVLLAPVISEKATLVADKNEQVVFEVAPDATKQEVKAAVELLFKVEVNSVNVLVSKGKAKRFGRFMGKRKDVKKAYVCLKPGQEINFEAEAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RS15_ACICJ
Sequence: MSITPDRRQELIGEYANKANDTGSPEVQVALLTERIVNLTEHLKTHAKDFHSRRGLLMLVGRRRRLLDYVKRQDVKRYEALIGRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CPSF1_CAEBR
Sequence: MYGYLRETDDSTAINYSAYGKFLPGENTGFQLLTIGAKFLRIFRVNPYVLKEPGEDNEEWQQKTKLECMFSCRLLNKCQSVAVARVPQLPDQDSILMTFDDAKLSIVAVNEKERNMQTISLHAFENEYLRDGFTTYFNPPIVRTDPANRCAASLVYGKHIAILPFHENSKRILSYIIPLKQIDPRLDNVADMVFLEGYYEPTILFLYEPLQTTPGRACVRYDTMCIMGVSVNIVDRQFAVVWQTANLPMDCNSLLSIPKPLGGAVVFGSNTIVYLNQAVPPCGIVLNSCYDGFTKFPLKDMKHLKMTLDCSTSVYMEDGRIAVGSREGDLYLLRLVTSSGGATVKSLEFSKVCDTSIAFTLTVCAPGHLFVGSRLGDSQLLEYTLLKVTKESAKKQRLEQQNPSEIELDEDDIELYGGAIEMQQNDDDEQISESLQFRELDRLLNVGPVKSMCFGRPNYMSNDLIDAKRKDPVFDLVTASGHGKNGALCVHQRSMRPEIITSSLLEGAEQLWAVGRKENESHKYLIVSRVRSTLILELGEELVELEEQLFVTNEPTVAAGELLQGALAVQVTSTCIALVTDGQQMQEVHIDSNFPVVQASIVDPYVAVLTQNGRPLLYELAMEPYVHLREVNVNETSFATFSEQISTQLTSVSIYSDASQIMKKNTVDGRDEKPENAAENGHHVAVPKIKKEIPDDDAMLYGEDDDFLYGDAEEDEPMVAAESGESSTRLQNTRKRKRLGHDAIMSSRGGEQSDAIDPTRTYSSITHWLVVAHDNGRITIHSLPDLELVYQIGRFSNVPELLVDMTVEEEEKEKKAKQTAAQEKEKETEKKKDDAKNEEDQVNSEMKKLCEKVVEAQIVGMGINQAHPVLIAIIDEEVVLYEMFASYNPQPGHLGVAFRKLPHLIGLRTSPYVNIDGKRAPFEMEMEHGKRYTLIHPFERISSINNGVMIGGAVPTLLVYGAWGGMQTHQMTIDGSIKAFTPFNNENVLHGFVYMTQQKSELRIARMHPDFDYDMPYPVKKIEVGKTVHNVRYLMNSDIYAVVSSVPKPSNKIWVVMNDDKQEEIHEKDENFVLPAPPKYTLNLFSSQDWAAVPNTEFEFEDMEAVTAMEDVPLKSESRYGGLDTYLALATVNNYGEEVLVRGRIILCEVIEVVPEPGQPTSNRKIKVLYDKEQKGPVTGLCAINGLLLSGMGQKVFIWQFKDNDLMGISFLDMHYYVYQLHSIRTIALALDARESMSLIRFQEENKAMSIASRDDRKCAQAPMASEFLVDGMHIGFLLSDEHGNITLFSYSPEAPESNGGERLTVKAAINIGTNINAFLRVKGHTSLLDSSSPEERENIEQRMNTIFGSLDGSFGYIRPLTEKSYRRLHFLQTFIGSVTPQIAGLHIKGARSSKPSQPIVNGRNARNLIDGDVVEQYLHLSVYDKTDLARRLGVGRYHILDDLMQLRRMAYYY
What is the function of this protein?
CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition.  This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).
What are the official names of this protein?
Probable cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor 160 kDa subunit, CPSF 160 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the CPSF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMN_ENTFA
Sequence: MQKESIYGLTREQLVDWFLAHGEKKFRATQVWEWLYTKRVASFSEMSNISKSLMTLLEENFSLNPLKQVIVQEAQDGTVKYLFELPDKNMIETVLMRQEYGLSVCVTTQVGCNIGCTFCASGLLKKQRDLTAGEIVAQIMWVQHYFDERGLDERVSHVVVMGIGEPFDNYANVMNFLRTINDDKGLAIGARHITVSTSGLVPKIREFADSGLQVNLAISLHAPNNEVRTSIMRINRSFPIEKLMAAIDEYIEKTNRRVTFEYIMLSQVNDRPEHAQQLADLLRNKKKLSYVNLIPYNPVSEHDQYSRSSKEAVLKFYDVLKKNGINCVIRKEHGTDIDAACGQLRSKQMKKEKVKNQ
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZC3HE_HUMAN
Sequence: MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTEPSSLKSSDTNIFDSNVPSNKSNFSRGDERRHEAAVPPLAIPSARPEKRDSRVSTSSQESKTTNVRQTYDDGAATRLMSTVKPLREPAPSEDVIDIKPEPDDLIDEDLNFVQENPLSQKKPTVTLTYGSSRPSIEIYRPPASRNADSGVHLNRLQFQQQQNSIHAAKQLDMQSSWVYETGRLCEPEVLNSLEETYSPFFRNNSEKMSMEDENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDYGSRTGSISSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVPQKQTLPVAPRTRTSQEELLAEVVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQRQLLSRLQIDPVMAETLQMSQDYYDMESMVHADTRSFILKKPKLSEEVVVAPNQESGMKTADSLRVLSGHLMQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEDMCFEGMKPVNQTAASNKGLRGLLHPQQLHLLSRQLEDPNGSFSNAEMSELSVAQKPEKLLERCKYWPACKNGDECAYHHPISPCKAFPNCKFAEKCLFVHPNCKYDAKCTKPDCPFTHVSRRIPVLSPKPAVAPPAPPSSSQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTINVPPRHALKWIRPQTSE
What is the function of this protein?
Involved in poly(A) tail length control in neuronal cells.  Binds the polyadenosine RNA oligonucleotides.
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 14, Mammalian suppressor of tau pathology-2, MSUT-2, Renal carcinoma antigen NY-REN-37.
What is the protein family that this protein belongs to?
Belongs to the ZC3H14 family.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Colocalizes with poly(A) RNA in nuclear speckles. SUBCELLULAR LOCATION: [Isoform 1]: Nucleus speckle. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus speckle. SUBCELLULAR LOCATION: [Isoform 6]: Cytoplasm.
Protein: 3MGH_BDEBA
Sequence: MILPQEFYFEDTTLVAQSLLGKVLNIRTDSGIQKARIIETEAYLGIEDPACHTFEDRRTERTKSMYLDGGHSYVYMIYGMYFCLNFVTRTHQHPEAVLIRAVEPLPAQENLRKKDLKTNGPGKLCKYYGITRKHDGLKLWKKSSDLYVTDEDFKVSKKQIIPTARVGVDYAGEAAKWPLRFYLRDHLFVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: MURC_STRPN
Sequence: MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRDFVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHFMPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDAPIYYYGFEAEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIGLLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKYPSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLANKINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_BRUA2
Sequence: MRLSRYFLPILKENPKEAEIVSHRLMLRSGMIRQQSAGIYSWLPIGLKVLNKVCTIIREEQNRAGANEILMPTIQSADLWRESGRYDAYGKEMLRIQDRQKREMLFGPTNEEMVTDIFRSYVRSYKDLPLNLYHIQWKFRDEVRPRFGVMRSREFLMKDAYSFDLDYEGAKMAYYRMFVSYLRTFARVGLQAIPMRADTGPIGGDLSHEFIILAETGESQVYCDRAYLDLAVPGADTDFRNDAQLTDIVTRWTTPYAATDEMHDEADWAKVKPESQVSARGIEVGHIFHFGTKYSEPMGAKVQGPDGKEHLVSMGSYGIGPSRLVAAAIEASHDDAGIIWPKTIAPFGAGIVNMKPGDEGCDGVSEKLYEALTNAGVDPLLDDKDERPGAKFATMDLIGLPTQVIVGPRGVAAGEVEVKDRKTGERQSLGIKAAINMLTAQA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_MYCPA
Sequence: MTASRSPATDLPKSWDPPAAEYAIYRQWVDAGYFTANPASDKPGYSIVLPPPNVTGSLHMGHALEHTMMDALTRRKRMQGYEVLWQPGMDHAGIATQSVVEKQLAVDGKTKEDFGRELFIEKVWDWKRESGGAIGGQMRRLGDGVDWSRDRFTMDEGLSRAVRTIFKRLYDAGLIYRAERLVNWSPVLQTALSDIEVNYEEVEGELVSFRYGSLDDSGPHIVVATTRVETMLGDTAIAVHPDDERYRHLVGSSLPHPFVDRQLLIVADEHVDPEFGTGAVKVTPAHDPNDFEIGLRHQLPMISIMDTRGRIADTGTQFDGMDRFAARVAVREALAAQGRIVEEKRPYLHSVGHSERSGEPIEPRLSLQWWVRVESLAKAAGDAVRNGDTVIHPTSMEPRWFAWVDDMHDWCVSRQLWWGHRIPIWYGPNGEQRCVGPDETPPEGWEQDPDVLDTWFSSALWPFSTLGWPEKTPELEKFYPTSVLVTGYDILFFWVARMMMFGTFVGDDDAITLDGRRGPQVPFTDVFLHGLIRDESGRKMSKSKGNVIDPLDWVDMFGADALRFTLARGASPGGDLAIGEDHVRASRNFCTKLFNATRYALLNGAQLAELPPLDELTDADRWILGRLEEVRAEVDSAFDNYEFSRACESLYHFAWDEFCDWYVELAKTQLAEGITHTTAVLATTLDTLLRLLHPVIPFITEALWQALTGNESLVIADWPRSSGIDLDQVATQRITDMQKLVTEVRRFRSDQGLADRQKVPARLAGVTESDLDTQVSAVTSLAWLTDAGPDFRPSASVEVRLRGGTVVVELDTSGSIDVAAERRRLEKDLAAAHKELASTTAKLANEDFLAKAPPHVVDKIRDRQRLAQEESERINARLAVLQ
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALL18_CARMA
Sequence: SDMYSFGL
What is the function of this protein?
May act as a neurotransmitter or neuromodulator.
What are the official names of this protein?
Carcinustatin-18.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.