PharMolix/UniProtQA huggingface dataset:
Protein: TSAC_VIBC3
Sequence: MALVENLQQAVDALRKGCVIAYPTEGVFGLGCDPDNQTAMLRLLAIKQRPVEKGVILIAASYAQLRPYVDETQLTAEQLTQVLASWPAPLTWVMPASGDTPSWVRGQFDTVAVRVSDHPVVQKLCLAFGKPLTSTSANLSGQPACVTQQEVMVQLGNQIAVVVEGKTSGRHGPSEIRDARSLQVLRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMYB_TRIRP
Sequence: MATSNKNMLLNYVPVYVMLPLGVINVNNVFEDPDGLKEQLVQLRAAGVDGVMVDVWWGIIEQKGPKEYDWSAYKSLFQLVQECGLKLQAIMSFHQCGGNVGDVVTIPIPQWVLDIGESDPDIFYTNRSGTRDKEYLTVGVDNKPIFHGRTAIEIYSDYMKSFRENMSEFLKSELIIDIEVGLGPAGELRYPSYPQNQGWVFPGIGEFQCYDKYLKADFKAAAAKAGHSEWELPDDAGTYNDIPESTEFFKTNGTYLTEKGKFFLTWYSNQLLNHGDQILDEANKAFLGCKVKLAIKVSGIHWWYKAQNHAAELTAGYYNLDDRDGYRPIAKMVSRHHGILNFTCLEMRDSEQSSDAQSAPQELVQQVLSGGWRENIEVAGENALSRYDATAYNQIILNARPQGVNKDGPPKLRMYGVTYLRLSDDLLQESNFEIFKKFVVKMHADQSHCDDPQEYNHAIPPLKRSGPNIPVDDLLEATKPILPFPWDSETDMKVDG
What are the official names of this protein?
Beta-amylase, 1,4-alpha-D-glucan maltohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 14 family.
Protein: UBP25_MOUSE
Sequence: MTVEQNVLQQSAAQKHQQTFLNQLREITGINDAQILQQALKDSNGNLELAVAFLTAKNAKTPPQEETGYYQTALPGNDRYISVGSQADANVIDLTGDDKDDLQRAIALSLAESNRAFRETGITDEEQAISRVLEASIAENKACLKRTPIEVWRDSRNPYDRKRQEKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRAVEILKDAFKSNDSQQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVELFYGRFLAMGVLEGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHSDNSGKSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNREITRIKREEIKRLKDYLTVLQQRLERYLSYGSGPKRFPLVDVLQYALEFASSKPVCTSPVDDIDASSSASGPLPSQSLPSTTEQQGPCASDLPGSSSPASGAALPLRSVIHKPFTQSRIPPDLPMHPAPRHITEEELCVLESCLHRWRTEIENDTRDLQESISRIHRTIELMYSDKSMIQVPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFGGYRNASAYCLMYIDDKAQFLIQEEFNKETGQALVGMETLPPDLRDFVEEDNQRFEKELEEWDTQLAQRSLQEKLLAAPKLREAEASATTAQAGGADYLEQPSRSDLSKHWKEETLRVIAKASHDLEDKGPETVLQSAIKLEYSRLVKLAQEDTPPETDYRLHHVLVYFIQNQAPKKIIEKTLLEQFGDRNLSFDERCHNIMKVAQAKLEMIKPEEVNLEEYEEWHADYKKFRETTMYLITGLENFQRESYIDSLLFLLCAYQNNKELLSKGPYRGHDGELISHYRRECLLKLNEQAAELFESGEDGDVNNGLIIMNEFIVPFLPLLLVDDMEEKDILAVEDMRNRWCSYLGQEMEANLQEKLTDFLPKLLDCSTEIKGFHEPPKLPSYSAHELCERFARIMLSLSRTPADGR
What is the function of this protein?
The muscle-specific isoform (USP25m) may have a role in the regulation of muscular differentiation and function.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 25, Deubiquitinating enzyme 25, Ubiquitin thioesterase 25, Ubiquitin-specific-processing protease 25, mUSP25.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The longer muscle-specific isoform (USP25m) Some transient punctuate nuclear location in myotubes during myocyte development.
Protein: HEPT_THECF
Sequence: MKRSHKDYLEDIAEAIELIEEFTREICFEDFLCDKKTQFAVIRALEIIGEASKNIPNDFKRLHPEIPWREMARMRDKLIHAYFGVDVRVLWKTVKEDIPSLKGKFEKLRK
What is the function of this protein?
Toxic component of a type VII toxin-antitoxin (TA) system.  Overexpression in E. coli inhibits cell growth.  Neutralized by cognate antitoxin MntA (PubMed:33045733).  Neutralization is probably due to AMPylation by MntA (Probable).  Probably an RNAase (By similarity).
What are the official names of this protein?
Probable ribonuclease HepT, Toxin HepT.
What is the protein family that this protein belongs to?
Belongs to the HepT RNase toxin family.
Protein: Y1452_MYCBO
Sequence: MTAAPNDWDVVLRPHWTPLFAYAAAFLIAVAHVAGGLLLKVGSSGVVFQTADQVAMGALGLVLAGAVLLFARPRLRVGSAGLSVRNLLGDRIVGWSEVIGVSFPGGSRWARIDLADDEYIPVMAIQAVDKDRAVAAMDTVRSLLARYRPDLCAR
What are the official names of this protein?
Uncharacterized protein Mb1452.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YHAM_ECOLC
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHDGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCARGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: RSMG_MARMM
Sequence: MDRETFGRETGVSRETLDGFETWRALLVETNAHTNLVGRSTLDQFWARHAMDSYQLLEHVGADVTKIADLGAGAGFPGIALALGLRDRQQAAHVTLVDSVGKKVAFLRKTIAALALDADARSVRVETLDPAEGFDLITARAFAPLNKLLGYASPLLKNRAQGLFFKGQNYRDELTEARKHWTFDCEVIPSRTSDGVILRIHEVERAN
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAFA5_RAT
Sequence: MAPSPRTSSRQDATALPSMSSTFWAFMILASLLIAYCSQLAAGTCEIVTLDRDSSQPRRTIARQTARCACRKGQIAGTTRARPACVDARIIKTKQWCDMLPCLEGEGCDLLINRSGWTCTQPGGRIKTTTVS
What is the function of this protein?
Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2 (PubMed:29453251).  Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway (By similarity).  Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes (By similarity).  Stimulation of macrophage migration and inhibition of osteoclast formation is mediated through the GPCR FPR2 (By similarity).  Acts as a adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling (PubMed:29453251).  Inhibits injury-induced cell proliferation and neointima formation in the femoral arteries (PubMed:29453251).
What are the official names of this protein?
Chemokine-like protein TAFA-5.
What is the protein family that this protein belongs to?
Belongs to the TAFA family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNMA_NITOC
Sequence: MNKPKVVVGLSGGVDSSVAALRLQQQGYPTSGLFMKNWVDFADESECTVAQDREDAQAVTSLLGISFHEANFAMEYWDRVFHYFLEEYRLGRTPNPDILCNREIKFKTFLDHALALGNTLIATGHYARIDQKEGRYRLLKGRDKNKDQSYFLYTLGQKQLSHTLFPLGELEKPQVRRIAIQARLPNHSKKDSTGICFIGERRFKEFLSRYLPAQPGEMRTPDKEWIGQHDGLMYYTLGQRRGLGIGGRKNSNGAPWFVVGKNLPQNTLYVAQGRHHPWLKSLILEANQLHWVAGHPPPLPYSCTAKIRYRQTDQHCTLTAIANGYIKVIFNAPQYAATPGQAIVFYQDDECLGGGTITTTDALGIQS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y891_SULAC
Sequence: MSALYDNEAKIRQAVGMLQKIVNDTSVPRNIRRAATDAIRNLQDQTLSPAVRAANAIGILEEISQDPNMPMHTRIAIWNVVSMLETVKD
What are the official names of this protein?
UPF0147 protein Saci_0891.
What is the protein family that this protein belongs to?
Belongs to the UPF0147 family.
Protein: HEM6_CROS8
Sequence: MAPDIQRVKAFLLDLQDRICQQLSAVDGDDFVEDAWQREGGGGGRSRVLRDGVVFEQAGVNFSHVHGDAMPASATAHRPELAGRSFEAMGVSLVVHPRNPYVPTSHANVRFFIAEKPGADPVWWFGGGFDLTPFYGFEEDAVHWHRTARDLCAPFGDDVYPRYKKWCDDYFYLKHRQEARGIGGLFFDDLNTPDFDTCFAFMQAVGDGYLNAYLPIVERRKTLPWGEREREFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYGYQPEENSPEAALYRDFLPVRDWVK
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_ANOFW
Sequence: MADVVKITFPDGAVKEFPKGVTTEDIAASISPGLKKKAIAGKLNERMIDLRTPIEEDGAISIITQDMPEALDILRHSTAHLMAQAVKRLYKDVKLGVGPVIENGFYYDIDVDVPITAEDLPKIEQEMKKIVKENLDIVRKEVSREEAIRRYEEIGDPLKIELINDIPEGEVVSIYEQGEFFDLCRGVHVPSTGKIKEFKLLSVAGAYWRGDSKNKMLQRIYGTAFFKKEDLDEYLRLLQEAKERDHRKLGKELDLFMTSQKVGQGLPLWLPKGATIRRTIERYIVDKELSLGYQHVYTPVLGSVELYKTSGHWDHYKDGMFPPMEMDNEQLVLRPMNCPHHMMVYKHKIHSYRELPIRIAELGTMHRYEMSGALTGLQRVRGMTLNDAHIFVRPDQIKDEFKRVVNLILDVYKDFGLTDYSFRLSYRDPQDKEKYYDDDAMWEKAQSMLKEAMDELGLDYYEAEGEAAFYGPKLDVQVRTALGKDETLSTVQLDFLLPERFDLTYIGEDGKPHRPVVIHRGVVSTMERFVAFLIEEYKGAFPTWLAPIQVQVIPVAPSIHMDYAYEVKHALQVAGIRVEVDEREEKIGYKIREAQMQKIPYMLVVGDNEVNERAVNVRKYGEQKSETMPLDAFVDSIAKEVRK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXYD3_HUMAN
Sequence: MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAKCKCKFGQKSGHHPGETPPLITPGSAQS
What is the function of this protein?
Decreases the apparent K+ affinity of the sodium/potassium-transporting ATPase only at slightly negative and positive membrane potentials and increases the apparent Na+ affinity over a large range of membrane potentials.
What are the official names of this protein?
FXYD domain-containing ion transport regulator 3, Chloride conductance inducer protein Mat-8, Mammary tumor 8 kDa protein, Phospholemman-like, Sodium/potassium-transporting ATPase subunit FXYD3.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: KYNB_BORBR
Sequence: MKRLWDISPPVSADSPVFPGDTPYRQQWKWSLTPDCPVNVSEITLSPHIGAHADAPLHYENGAAAIGAVALEPFLGPCRVIHAIGCGPLILPEHLAHAQAGLPPRVLVRTARHAALQWWVDDFSAYAPQTIEWLAGRGVTLIGIDTPSIDPASSKTLDSHHAIRRHDMRVLENLRLDDVDEGDYELIALPLALVQADASPVRAVLRELA
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: INUB_ASPNG
Sequence: MLNPKVAYMVWMTCLGLTLPSQAQSNDYRPSYHFTPDQYWMNEPNGLIKIGSTWHLFFQHNPTANVWGNICWGHATSTDLMHWAYKPTAIADENGVEAFTGTAYYDPNNTSGLGDSANPPYLAWFTGYTTSSQTQDQRLAFSVDNGATWTKFQGNPIISTSQEAPHDITGGLESRDPKVFFHRQSGNWIMVLAHGGQDKLSFWTSADTIHWTWQSDLKSTSINGLSSDITGWEVPDMFELPVEGTGETTWVVMMTPAEGSPAGGNGVLAITGSFDGKTFTADPVDASTMWLDNGRDFDGALSWVNVPASDGRRIIAAVMNSYGSNPPTTTWKGMLSFPRTLSLKKVGTQQHFVQQPITELDTISTSMQTLANQTITPGQTLLSSIRGTALDVRVAFYPDAGSVLSLTVRKGASEQTVINYTQSNATLSVDRTESGDISYDPAAGGVHTAKLEEDGTGLVSIRVLVDTCSVEVFGGQGEAVISDLIFPSDSSDGLALEVTGGNAVLQSVDVRSVSLE
What is the function of this protein?
Endo-inulinase involved in utilization of the plant storage polymer inulin, consisting of fructooligosaccharides with a degree of polymerization (DP) value from 2 to 60.
What are the official names of this protein?
Extracellular endo-inulinase inuB.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPB_PARMW
Sequence: MTSTLPNASTPDPASLQPSVRPGAHGRFGRFGGQYVPETLMPALAELEQAAAQAWNDPAFTAELNQLLKNYVGRATPLYEAERLTAHYRRADGGPRIWLKREDLNHTGAHKINNALGQALLALRMGKKRIIAETGAGQHGVATATVCARFGLECVIYMGAEDMRRQALNVFRMRLLGATVQPVTAGTATLKDATSEAIRDWVTNVESTHYILGSVAGPHPYPMLVRDFHAVIGQEARQQCREAFGRLPDVLMACVGGGSNAMGLFHPFVECTNVRLIGVEAAGDGVATGRHAATITEGRAGVLHGAMSLLLQDSDGQVQEAHSISAGLDYPGVGPEHSYLREIGRAEYGAVTDQQALGALRLVSELEGIIPALETAHAFAWLEQLCPTLPDGSEVVINCSGRGDKDVNTVAEKLGDQL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PYRG_COPPD
Sequence: MTNTKFVFVTGGVLSSVGKGIAAASMGMLFKARGYKVTAIKMDPYLNVDAGTMSPYQHGEVFVTEDGAETDLDLGHYERFLDENLSGKNNITSGKIYSQVITKERKGDYLGSTVQVIPHVTDAIKESILYGAQGADLAVVEIGGTVGDIESLPFLEAVRQLRRELGPNGSVVVHVTYVPILETTHEAKTKPTQHSVKELRSIGLQPDAIVLRSHTPLEKHVLEKTSLFCDVPLEGVINSYDVESVYDVPLLLEQEKLISVLEERLFGTTTEADLKKWKEMLSRQSERTLKVALVGKYVVLPDAYLSVIEAIRHAAMKLGVAAHVSLMSSDELEKCDDEQLSEKLSNMDALVVPGGFGARGIEGMVKVLRYARENKMPTLGLCLGMQVMSIEFARNVLGLKDANSTEFDPNTTYPVISLLPEQMQVRDLGGSMRLGAYPCTLVEGTRVHALYNKPVVFERHRHRFEFNNEFREAFENNGFQVSGLYEPKDLVEVLELKDHPFYVGVQYHPEFKSRPMVPHPLFLGLLSEAVAKASPVL
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: OST1_YEAST
Sequence: MRQVWFSWIVGLFLCFFNVSSAAQYEPPATWENVDYKRTIDVSNAYISETIEITIKNIASEPATEYFTAFESGIFSKVSFFSAYFTNEATFLNSQLLANSTTAPGDDGESEIRYGIIQFPNAISPQEEVSLVIKSFYNTVGIPYPEHVGMSEEQHLLWETNRLPLSAYDTKKASFTLIGSSSFEEYHPPNDESLLGKANGNSFEFGPWEDIPRFSSNETLAIVYSHNAPLNQVVNLRRDIWLSHWASTIQFEEYYELTNKAAKLSKGFSRLELMKQIQTQNMRQTHFVTVLDMLLPEGATDHYFTDLVGLVSTSHAERDHFFIRPRFPIFGGWNYNFTVGWTNKLSDFLHVSSGSDEKFVASIPILNGPPDTVYDNVELSVFLPEGAEIFDIDSPVPFTNVSIETQKSYFDLNKGHVKLTFSYRNLISQVANGQVLIKYDYPKSSFFKKPLSIACYIFTALMGVFVLKTLNMNVTN
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, N-linked oligosaccharyl transferase subunit 1, Oligosaccharyl transferase 64 kDa subunit, Oligosaccharyl transferase subunit OST1, Oligosaccharyl transferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the OST1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: DHOM_HELPJ
Sequence: MKKRLNIGLVGLGCVGSTVAKILQENQEIIKDRAGVEIKIKKAVVRDVKKHKGYAFEISDDLESVIEDKGIDIVVELMGGVEAPYLLAKKTLAKQKAFVTANKAMLAYHRYELEQIAKNTPIGFEASVCGGIPIIKALKDGLSANHILSFKGILNGTSNYILSQMFKNQASFKDALKDAQHLGYAELNPEFDIKGIDAAHKLLILASLAYGIDAKLEEILIEGIEKIEPDDMEFAKEFGYSIKLLGIAKKHQDCIELRVHPSMIKNECMLSKVDGVMNAISVIGDKVGETLYYGAGAGGEPTASAVISDIIEIARKKSSLMLGFETPQKLPLKPKEEIQCAYYARLLVSDEKGVFSQISAILAQNDISLNNVLQKEIPQSNKAKILFSTHTTNEKSMLNALKELENLQSVLDTPKMIRLEN
What are the official names of this protein?
Homoserine dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the homoserine dehydrogenase family.
Protein: PORTL_PSHV1
Sequence: MEGGCSFAQNLRFGEGREASRRPPVMETLEIIDPTLSTGNDGGEWLLIHPTQRTMGFREVLLGAPAYSPGHGIYNAVRATSTVIRQVQASVLRNILDGVAFEDLADDWRAHISARGFAPGDLAEKYWLEPADAVRVAENATETWSFLLRNLLLDFVRRVAEYCIDGMGGADGTAAYARYVDWLTCLGIVPVIREGDVADDSAGKGTERFVADTEWDLSMQNRLRLAPAITRRGYDMLGCLERCFRAARVMNYDRTVVIMHSATRELRAYDVHTRERGGCVVAWDPMLTERGIVFDSPMQRLYAAVLRTQAVREHAKLCQLANTAPVSVLVARREDKVAADPAGVSKLVDKALGEGAEEAGQSAAAKLIKFIIDMQNMRKVGDVAEVVDAYLRESGGPAIDKTFSLDPGRAGFGGNGKSAQGLLGQQGQPNQPKDGVASVMRDAVNTSVGKVVNNLFKAVSDLKSANADLTRRNAHIAKELTESRRRIGALTSAAARDNSNGSSRYDAPDAWRVLDEKDARWEMGDTLLSLGNLPESVTMNKVDLSGEMTEDQYVANSFFSRYVPPYLEEESRLSALWERELLRVFKMHRVTNNQGDEVSISYSNSSISLIVGPFFHRVLKATRLGFLVADDEAYKSEEELCESLFKKSRVDAYLRDLKTTYLADVRNACAIRKIRQEPFLREPQDVSGEFERAGVGADYIDGAETAPWPGDDTRKKWDLANRGLCRGGPARQRVEWERGEDHGQLGERDVRRSVPRWWRTTPYPTREDQRSGRGRRGMRQLR
What is the function of this protein?
Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging.  Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid.  Binds to the molecular motor that translocates the viral DNA, termed terminase.
What are the official names of this protein?
Portal protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae portal protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: VE6_HPV21
Sequence: MADSSTDSADEGPSPKRRHLEEENTSSFLEPPLPATIRDLANLLEIPLDDCLVPCNFCGNFLTHLEVCEFDEKKLSLLWKDHCVFACCRVCCAATATYEYNEFYESTVVGRDIEEITGKSIFDIDVRCYTCMKFLDSIEKLDICGRKHFFHKVRGTWKGICRLCKHFQ
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RL35_PORG3
Sequence: MPKLKTNSGAKKRFALTGTGKIKRKHAFKSHILTKKTKKQKRNLTYFSTVHKVDENAVKQLLCLR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: BOR6_ARATH
Sequence: MKSEGESGPFQGILRDIEGRRKCYKQDWIRGIKTGIRILAPTCYIFFASSLPVVAFGEQLSKHTGGALSAVETLASTSICGIIHAIFGGQPLLIVGVAEPTIIMYTYLYSFCISRPDIGRELYLAWVAWVCVWTSVLLILLSIFNAGTIITRFTRIAGELFGMLIAVLFLQEAIKGLISEFHAPEIKNQETGKSHFLLIYANGLLAVIFSLGLLITALKSRRAKSWKYGFGWLRSFIGDYGVPLMVLLWTALSYTVPSEVLPSVPRRLFCPLPWEPASLYHWTVVKDMGKVPIMYILAAFIPGVMIAGLYFFDHSVASQMAQQKEFNLKNPSAYHYDIFLLGIITLICGLLGLPPSNGVLPQAPMHTKSLAVLNRQLIRKKMVKKAKECMKMKASKSEIYGRMQSVFIEMETSPPQDNSVATDLKELKEVVMRPDEGGDTKGKFDPDVHIEANLPVRVNEQRVSNLLQSVLVGLTLLAVTVIKMIPSSVLWGYFAYMAIDSLPGNQFWERLLLLFIPPSRLFKVLEGVHASFVELVPYRVIVTFTLFQLVYFLLCYGMTWIPMAGIFFPALFFLLISIREHLLPKLFDMQHLQVLDASDYEEIVAAPIQHSSFAYRKLGSSHHLSEGEDEFYDAEILDEMTTSRGEIRIRTISFKEVHPEPEEKHVTFEPH
What is the function of this protein?
Probable boron transporter.  Boron is essential for maintaining the integrity of plants cell walls (By similarity).
What are the official names of this protein?
Probable boron transporter 6.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OORD_MOOTA
Sequence: MSTKDLFAEPNLKQITVWARGVVMNKDARDIVVALTEAAAKEGKYVQAWENYVDLPDRIYVPVRAYARISSDPIESKYIYENETPDIVVLVEESLIKGVPILKGIRPGSTLVVNTKRSIDTILEFLGDTGNLAQIVTVDANSMAEAVMTLSGAEGATDATGIGAGIAAPIAGAVVKATGIVDVENLAAVVKNPAAMRRGYAEAQVRQLPPHEAVEEAAVSATELLRQMPFAGTVPSPVTENEGMVTGNWRIQRPIIDREACTECYTCWIYCPDSCITRTEEGPVFNMKYCKGCGLCTAVCPSGALTNVPELDFKD
What is the function of this protein?
Catalyzes the anaerobic oxidation of oxalate using a broad range of electron acceptors, including ferredoxin and the nickel-dependent carbon monoxide dehydrogenase.  Does not require coenzyme A as cosubstrate.  Enables anaerobic growth on oxalate which is used as energy source by the bacteria.
What are the official names of this protein?
Oxalate oxidoreductase subunit delta, OOR delta subunit.
Protein: LYTS_BACAN
Sequence: MLNLVLMMIERVGLIVILGFLLSHIKTFRRLLHKQDGYVDKLKLICIFSVFTIVSNYTGIEIAGNTIMNENWLQGVSSSSTIANTRIMGVGISGLLGGPIVGIGVGSIAGIHRYMLGGTTALSCAISSILAGVITGYIGYIFKKYNRTITPKFSAVLSVFIVSLEMIMILLIVEDGISIVKTIAIPMILVNSFGSFILLSMIQAILRQEENAKALQTHKVLRIADKTLPYFRQGLTEESCKHVAQIIHRFTGTDAVSLTDTEKILAHVGLASDHHIPSHSLITGLSKEVLHTGKIMKAKSREVINCQHEGCPLQAAIVIPLTSHGNTIGTLKLYFKNPNQLSRVEEELAEGLAKIFSTQLELGEAELQSKLLQDAEIKALQAQINPHFLFNAINTVSALCRTDVEKARKLLLQLSVYFRCNLQGARQLLIPLEQELNHVQAYLSLEQARFPNKYEVKMYIEDELKTTLVPPFVLQLLVENALRHAFPKKQPVCEVEVHVFEKEGMVHFEVKDNGQGIEEERLEQLGKMVVSSKKGTGTALYNINERLIGLFGKETMLHIESEVNEGTEITFVIPKKVGEEEQIVKSISS
What is the function of this protein?
Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.
What are the official names of this protein?
Sensor protein LytS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSB_ARCFU
Sequence: MSMIEEKIYKGTTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIKIEANLYEIRRERKPTVRAIATLTSNLLNSYRYFPYLVQLLIGGIDSEGKSIYSIDPIGGAIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGIDVVKITEDEFYQYSPEEVEQILAKFRK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 14334_SOLLC
Sequence: MADSSREENVYLAKLAEQAERYEEMIEFMEKVAKTADVEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEDHVNTIKEYRSKIEADLSKICDGILSLLESNLIPSASTAESKVFHLKMKGDYHRYLAEFKTGTERKEAAENTLLAYKSAQDIALAELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAISELDTLGEESYKDSTLIMQLLRDNLTLWTSDNADDVGDDIKEASKPESGEGQQ
What are the official names of this protein?
14-3-3 protein 4, PBLT4.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: CAPSD_BPAL3
Sequence: MSNVQTSAEREIVDLSHLAFDCGMLGRLKTVSWTPVIAGDSFELDAVGALRLSPLRRGLAIDSKVDFFTFYIPHRHVYGDQWIQFMRDGVNAQPLPSVTCNRYPDHAGYVGTIVPANNRIPKFLHQSYLNIYNNYFRAPWMPERTEANPSNLNEDDARYRFRCCHLKNIWSAPLPPETKLAEEMGIESNSIDIMGLQAAYAQLHTEQERTYFMQRYRDVISSFGGSTSYDADNRPLLVMHTDFWASGYDVDGTDQSSLGQFSGRVQQTFKHSVPRFFVPEHGVMMTLALIRFPPISPLEHHYLAGKSQLTYTDLAGDPALIGNLPPREISYRDLFRDGRSGIKIKVAESIWYRTHPDYVNFKYHDLHGFPFLDDAPGTSTGDNLQEAILVRHQDYDACFQSQQLLQWNKQARYNVSVYRHMPTVRDSIMTS
What is the function of this protein?
Assembles to form an icosahedral capsid with a T=1 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins F.  Upon virus binding to host cell, one of the spikes dissociates from the capsid and the virus interacts with LPS through the exposed EF loops on the F proteins.  After the genome had been ejected, the channel formed by the F proteins at the unique fivefold axis remains open.
What are the official names of this protein?
Capsid protein F, F protein, GPF.
What is the protein family that this protein belongs to?
Belongs to the microviridae F protein family.
What are the subcellular locations of this protein?
Virion.