PharMolix/UniProtQA huggingface dataset:
Protein: NFUA_PHOLL
Sequence: MINITEAAQTHFAKLLANQEPGTQIRVFVINPGTPTAECGVSYCPPDAVEATDTELKFDQLSAYVDELSAPFLEEAEIDFVTDQLGSQLTLKAPNAKMRKVSDDSPLAERVEYVLQSQINPQLAGHGGRVSLMEITDDGFAILQFGGGCNGCSMVDVTLKEGIEKELLNMFPELKGVKDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: HUTI_PSEPG
Sequence: MRTLWQHCHVATMAEGRYSAIEDAAIVTSAGLIEWIGPRAELAPVEADRTVDLGGAWVTPGLIDCHTHAVFGGNRSGEFEQRLQGVSYAEIAAQGGGIASTVRATRAASEDELFASARQRVQALMRDGVTTIEIKSGYGLDLANERKMLRVARRLADELPLAVRATCLAAHALPPEYAGRADDYIAHICDEMLPALAAEGLVDAVDAFCEHLAFSPAQVERLFIKARALGLPVKLHAEQLSSLHGSSLAARYQALSADHLEFMTEEDAIAMAKAGTVAVLLPGAFYFLRETQLPPMDALRRHGVKIALASDLNPGTSPGLSLRLMLNMGCTCFRMTPEEALAGVTVHAATALGLGDSHGSLEVGKVADFVAWQIERPADLAYWLGGDLPKRVVRKGHEISN
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRAF_MOUSE
Sequence: MAALSGGGGSSSGGGGGGGGGGGGGDGGGGAEQGQALFNGDMEPEAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLVFQTPTDASRNNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPVPQEEASFPETALPSGSSSAPPSDSTGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSSSEDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGGFPVH
What is the function of this protein?
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus.  Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway.  May play a role in the postsynaptic responses of hippocampal neurons.
What are the official names of this protein?
Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes.
Protein: KCIP4_MACFA
Sequence: MNVRRVESISAQLEEASSTGGFLYAQNSTKRSIKERLMKLLPCSAAKTSSPAIQNSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI
What is the function of this protein?
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels.  Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner.  Modulates KCND3/Kv4. 3 currents.  Isoform 4 does not increase KCND2 expression at the cell membrane.  Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.
What are the official names of this protein?
Kv channel-interacting protein 4, KChIP4, A-type potassium channel modulatory protein 4, Potassium channel-interacting protein 4.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm.
Protein: BCHI_CERS4
Sequence: MKKPFPFSAIVGQEQMKQAMVLTAIDPGIGGVLVFGDRGTGKSTAVRALAALLPLIKAVEGCPVNSARPEDCPEWAHVSSTTMIERPTPVVDLPLGVTEDRVVGALDIERALTRGEKAFEPGLLARANRGYLYIDEVNLLEDHIVDLLLDVAQSGENVVEREGLSIRHPARFVLVGSGNPEEGELRPQLLDRFGLSVEVRSPRDVETRVEVITRRDAYDADHDAFMEKWGAEDMQLRGRILGARAALPQLKTPNTVLHDCAALCIALGSDGLRGELTLLRAARAQAAFEGAEAVGRSHLRSVATMALSHRLRRDPLDEAGSVSRVERCVAEVLP
What is the function of this protein?
Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
What are the official names of this protein?
Magnesium-chelatase 38 kDa subunit, Mg-protoporphyrin IX chelatase.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
Protein: TIG_SERP5
Sequence: MQVSVETTQGLGRRLSITVPADTIKQAIKKELINAAKSVRIDGFRKGHVPMNIVEQRYGASVRQDVLGDAMQRSFVDAIIKEKINPAGAPNYVPGEYKEGEDFTFAVEFEVYPEVELKGLDGIEVEKPVVEVNDADVDTMLDTLRKQQATWKETDRAAQAEDRVTVDFSGSIDGEEFEGGKASDFVLAMGQGRMIPGFEEGLVGHKAGEEFTIDVNFPEDYHAENLKGKAAKFAIVLKKVEERELPELTEEFIKRFGVADGSTEGLRAEVRKNMERELKGAVRNRIKTQAIDGLVSANEIDVPAALIDGEVDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVISTNDLKADEDRVKTLIEEMASAYEDPSEVVEFYSKNKELMNNMRNVALEEQAVEALLAKAKVTEKATTFSELMNQTQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ULAD_SHIF8
Sequence: MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: MRAZ_SHEWM
Sequence: MFRGASAINLDTKGRVAIPKRYREPLHVEYNSQLVITVDIQSACLLLYPLDEWSKIEAKLLLLSDTLPAERAMKRMLLGYAHECELDGNGRLLLPLPLRQYANLGKRAMLVGQLNKFELWDETAWQHQIEQSRETIQDEEFAENIRLADFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL15_BURM9
Sequence: MELNNLKPAEGAKHAKRRVGRGIGSGLGKTAGRGHKGQKSRSGGFHKVGFEGGQMPLQRRLPKRGFTSLTKEFVGEVRLGDLEKLPVDEIDLLALKQAGLVGELIKSAKIIATGELKRKIVVKGLGATKGARAAIEAAGGSFAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: THSD4_HUMAN
Sequence: MVSHFMGSLSVLCFLLLLGFQFVCPQPSTQHRKVPQRMAAEGAPEDDGGGGAPGVWGAWGPWSACSRSCSGGVMEQTRPCLPRSYRLRGGQRPGAPARAFADHVVSAVRTSVPLHRSRDETPALAGTDASRQGPTVLRGSRHPQPQGLEVTGDRRSRTRGTIGPGKYGYGKAPYILPLQTDTAHTPQRLRRQKLSSRHSRSQGASSARHGYSSPAHQVPQHGPLYQSDSGPRSGLQAAEAPIYQLPLTHDQGYPAASSLFHSPETSNNHGVGTHGATQSFSQPARSTAISCIGAYRQYKLCNTNVCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQAMGYRFYVRQAEKVIDGTPCDQNGTAICVSGQCKSIGCDDYLGSDKVVDKCGVCGGDNTGCQVVSGVFKHALTSLGYHRVVEIPEGATKINITEMYKSNNYLALRSRSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEISSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEYVIMGTNAISPQVPPHRRPGEPFNGQMVTEGRSQEEGEQKGRNEEKEDLRGEAPEMFTSESAQTFPVRHPDRFSPHRPDNLVPPAPQPPRRSRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRSTHEEAPESYCDSSMKPTPEEEPCNIFPCPAFWDIGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPETTSTCQLKICSEWQIRTDWTSCSVPCGVGQRTRDVKCVSNIGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSERCSAECGAGVRTRSVVCMTNHVSSLPLEGCGNNRPAEATPCDNGPCTGKVEWFAGSWSQCSIECGSGTQQREVICVRKNADTFEVLDPSECSFLEKPPSQQSCHLKPCGAKWFSTEWSMCSKSCQGGFRVREVRCLSDDMTLSNLCDPQLKPEERESCNPQDCVPEVDENCKDKYYNCNVVVQARLCVYNYYKTACCASCTRVANRQTGFLGSR
What is the function of this protein?
Promotes FBN1 matrix assembly.  Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN.
What are the official names of this protein?
Thrombospondin type-1 domain-containing protein 4, A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6, ADAMTS-like protein 6, ADAMTSL-6.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: LEU1_METPB
Sequence: MANTTESAKDRVVIFDTTLRDGEQCPGATMTLDEKLAVAELLDAMGVDIIEAGFPIASNGDFEAVSEIARRTKRATIAGLARAIPADIARAGEAVRHAKAGRIHTFVSTSAIHLAHQMRKTQDEVIEIILKTVTQARDLVEDVEWSAMDATRTDIDYLCRCVEAAIRSGATTINLPDTVGYATPQEYGAMFRQVRERVPNSDKAIFSVHCHNDLGLAVANSLAGLEGGARQIECTVNGIGERAGNAALEEIVMAIRTRADVMPYDTGIDTTMLTRASKLVSHAANFPVQYNKAIVGRNAFAHESGIHQDGMLKHSETYEIMTPASVGLSKTSLVMGKHSGRAAFKSKLAELGISLSDNQFQDVFERFKDLADRKKHVYDEDIEALVDEKLATAHDRIKLLSLSVIAGTRGPQRATMKIEMDGRTFTEEADGNGPVDAVFNAIHEIVPHDAVLELYQVHAVTEGTDAQAEVSVRLKAGERSVTARGADPDTLVASAKAYLSALNKLSAASVRLHAQHAAVV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: EI2BD_DICDI
Sequence: MSSFGKNSSYRDTGASLKELGDYLDSKQEGKPTHQKTIGFDTNTSPVSIPTIISPPLGSNNSNYGKSPKSSYDNKQTSPLLSASNNRKNNNNNNNNNNATSPKDSSIIGKNNVNSDLSKVSSSLNELKFEKQPIGSTSSTPTSTPSSTPSSSTPSSTPSTPNTNSQQQQQQQQQQKKQQQQQPKQPQQPKQQSKQQATQQDKKDKEQQQQQQDKQDKESNEIKGSKEVAKDGQHGVKQFDDPKQRGKITKKKIIKVGESSRSVQLFNHLPQYNSEFSMGVSVSTDEPNEKYPIHPDIISLGLKYAEFKIAGSNARAIAMMTAFIQIFKDYVAAPDKVYSRELDSLLKRNIQFLVDCRPISISMGNSINYVKHKLSLTNNMSHEGARDYLIKSINEFIERIQMADNAIVKHGCSKINDGDVILTYASSHVVELIIQQAIQDKKKFRLIIVDSRPKHEGRELLHRLVLHGVKITYIMLHAVSYIMKEVTKVFVGAYSVLSNGNLISRSGTSLVASMAKFYNVPFIVCCETYKFTERVQLDSICFNQIGNPQDLVQNLGEKEGSKSLLENWESYSTLKLLNLMYDLTPIELIDMVITEFGMLPPTSIPVVLREYRKEVISIN
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit delta, eIF-2B GDP-GTP exchange factor subunit delta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: GLGB_ECOK1
Sequence: MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPIYRQYHHDKLTFGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGAVHSDEIASHGRQHSLSLTLPPLATIWLVREAE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: HFLC_VIBPA
Sequence: MRKLMIPVLVIALALMLMSLFVIPEGERGIVVRFGRVLKDNNDITRIYEPGLHFKMPLFDRVKQLDARIQTMDGRADRFVTSEKKDVIIDSYVKWRIEDFGRYYLATGGGNSLTAEALLERKVTDVLRSEIGAREIKQIVSGPRNDDVLPEDASSDEVNTEAAREALEIDGERDLIMSDVLRDTRESAMKDLGVRVVDFRMKKINLPDEISESIYRRMRAERESVARKHRSQGREKAEIIRAQAELEVATILAEADKTARVTRGEADAEAAKIYANAYNKDPEFFSFLRSLRAYEKSFSSKNDILVLDPKSDFFQYMNNAKGAKAE
What is the function of this protein?
HflC and HflK could regulate a protease.
What are the official names of this protein?
Protein HflC.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. HflC subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS27A_METMA
Sequence: MAVKDYYKVQGDSVTRLKQFCPRCGPGVFLADHKNRLACGKCGYTEFKK
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: ELOV7_MOUSE
Sequence: MAFSDLTSRTVRFYDNWIKDADPRVEDYLLMSSPLPQTIILGLYVYFVTSLGPKLMENRKPFELKKAMITYNFFIVLFSVYMCYEFVMSGWGTGYSFRCDIVDYSQSPRAMRMVHTCWLYYFSKFIELLDTIFFVLRKKNSQVTFLHVFHHTIMPWTWWFGVKFAAGGLGTFHAFLNTAVHVVMYSYYGLCAMGPAYQKYLWWKKHLTSLQLVQFVLVTIHIGQIFFMEDCNYQYPVFLYIIMSYGCIFLLLFLHFWYRAYTKGQRLPKTLENGNCKSKRH
What is the function of this protein?
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle.  Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs.  Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA.  Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs.  May participate in the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
What are the official names of this protein?
Elongation of very long chain fatty acids protein 7, 3-keto acyl-CoA synthase Elovl7, ELOVL fatty acid elongase 7, ELOVL FA elongase 7, Very long chain 3-ketoacyl-CoA synthase 7, Very long chain 3-oxoacyl-CoA synthase 7.
What is the protein family that this protein belongs to?
Belongs to the ELO family. ELOVL7 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: OSTB_YEAST
Sequence: MRTDWNFFFCILLQAIFVVGTQTSRTLVLYDQSTEPLEEYSVYLKDLEQRNYKLEYLDINSTSTTVDLYDKEQRLFDNIIVFPTKGGKNLARQIPVKQLIKFFENEGNILCMSSPGAVPNTIRLFLNELGIYPSPKGHVIRDYFSPSSEELVVSSNHLLNKYVYNARKSEDFVFGESSAALLENREQIVPILNAPRTSFTESKGKCNSWTSGSQGFLVVGFQNLNNARLVWIGSSDFLKNKNQDSNQEFAKELLKWTFNEKSVIKSVHAVHSHADGTSYDEEPYKIKDKVIYSVGFSEWNGEEWLPHIADDIQFELRQVDPYYRLTLSPSGNDSETQYYTTGEFILPDRHGVFTFLTDYRKIGLSFTTDKDVKAIRHLANDEYPRSWEISNSWVYISAICGVIVAWIFFVVSFVTTSSVGKKLETFKKTN
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1, Oligosaccharyl transferase subunit WBP1, Oligosaccharyl transferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the DDOST 48 kDa subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: UPP_BRUA1
Sequence: MGVTVVSHPLVKHKLTIMRKKETSTASFRRLLKEISLLLCYEVTRNLELTTMSIETPLMPMEAPVLEGKKLVFASILRAGNGLLEGMLDLVPAARVAHIGLYRDHDTLQPIEYYFKAPEDIVNRLVIVVDPMLATANSAIAAIDKLKERGATNIRFLCLLAAPEGIERFTKAHPDVEVFTASIDECLDEKGYIVPGLGDAGDRMYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SYGA_CROS5
Sequence: MSINFQEIIAKLNEFWSDRSCLIVQPYDTEKGAGTMSPHTFLRAIGPEPWSVAYVEPCRRPTDGRYGENPNRFQHYFQYQVLIKPSPDDIQEIYLDSLRALGIKPEDHDIRFVEDNWESPTLGAWGVGWEVWLDGMEITQFTYFQQCGGIDCRPVSIEITYGLERLAMYLQEVEAITKIQWNDQIKYGDIFLQSEVEQCTYNFEASDADLLFKLFALYEQEAKQLIDRGLVFPGLDYVLKCSHSFNLLDARGVIAVAERTRYIGRIRNLAREVANLYLQQRERLNFPLQKS
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPL_STRSQ
Sequence: MQLMKSSYLELTARGHVTDLLKPDDTLEMLETYGFAVTQSPVEAVSTAHAYREIAAIREDFGLGEPYVPLLYRDRDEPTVTAVTRKGGSDHPVFHTGEAQGWHTDGLLEDIGTIKTTLLYCVSPAHRGGRTFLLNAGRVFEELRMEDPEAADVLLRDTILGRRSTIPGVDREAVGPVFLELGDGHYATRYGEGRVERWYPADAAEQHALDRALRFFRARRDDPDVRIDLLLRAGQCLIFRNDVLAHGRENFTDDPQRPRLLLRSLHTNAPKKPS
What is the function of this protein?
Catalyzes the dephosphorylation and oxidation of UMP to generate 5'-dehydrouridine, the first intermediate in the biosynthesis of the liposidomycin-like A-90289 antibiotic.
What are the official names of this protein?
Uridine-5'-phosphate dioxygenase, Fe(II)-dependent alpha-ketoglutarate:uridine-5'-monophosphate dioxygenase, Fe(II)-dependent alpha-KG:UMP dioxygenase, UMP:alpha-ketoglutarate dioxygenase.
Protein: YFHJ_BACSU
Sequence: MNMYIEKLTNLLLEKNEMISYIQAKTWVELLWSDFEATYAKAGHAYQGEKMTEKIVTQWIENYGGQLHLFQSSRNDVNDYLNQSRGLLH
What are the official names of this protein?
Uncharacterized protein YfhJ.
Protein: HBAZ_MOUSE
Sequence: MSLMKNERAIIMSMWEKMAAQAEPIGTETLERLFCSYPQTKTYFPHFDLHHGSQQLRAHGFKIMTAVGDAVKSIDNLSSALTKLSELHAYILRVDPVNFKLLSHCLLVTMAARFPADFTPEVHEAWDKFMSILSSILTEKYR
What is the function of this protein?
The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit zeta, Alpha-like embryonic globin chain x, Hemoglobin zeta chain, Zeta-globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: 1433I_PLAF7
Sequence: MATSEELKQLRCDCTYRSKLAEQAERYDEMADAMRTLVEQCVNNDKDELTVEERNLLSVAYKNAVGARRASWRIISSVEQKEMSKANVHNKNVAATYRKKVEEELNNICQDILNLLTKKLIPNTSESESKVFYYKMKGDYYRYISEFSCDEGKKEASNCAQEAYQKATDIAENELPSTHPIRLGLALNYSVFFYEILNQPHQACEMAKRAFDDAITEFDNVSEDSYKDSTLIMQLLRDNLTLWTSDLQGDQTEEKSKDEGLE
What is the function of this protein?
Adapter protein which binds to its partners, usually via a phosphoserine or phosphothreonine motif (PubMed:23308157, PubMed:32484216, PubMed:32817103).  Binding generally results in the modulation of the activity and/or cellular localization of the binding partner (Probable).  Via its interaction with CDPK1 and PKAr, involved in merozoite microneme secretion and thus in merozoite invasion of host erythrocytes (PubMed:32817103).
What are the official names of this protein?
14-3-3 protein I, Pf14-3-3I.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Nucleus.
Protein: RLMH_MYCS5
Sequence: MTINLIAVGKLEKDFQKLFDEYAKRIFVFSKFNLIEIKENTLKNLEVKKEKETLEILSKIPKNSTVFLLSIKGKNYSSEEFSKLITNDANITFVIGGSNGVIESYFENKISFSKLTFPHQLFRVILIEQIYRAFTIKNNLKYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_CUPNH
Sequence: MTYALLNKIDAPADLRKLDRRELRTLADELRAYVLESVSQTGGHLSSNLGTVELTIALHYVFNTPDDRLVWDVGHQSYPHKILTGRRERMGTLRQWGGISGFPRRSESEYDTFGTAHSSTSISAALGMALGARTLGEKRVSVAVIGDGAMTAGMAFEALNNAGVYKDLPLVVVLNDNDMSISPPVGALNRHLARLLSGQFYAATKKGIEKVLSVAPPVLEFAKRFEEHAKGMMVPATLFEEFGFNYIGPIDGHDLNSLVPTLQNIRERALEGAGPQFLHVVTKKGQGYKLAEADPILYHGPGKFNPAEGIRPAAKPARKTYTQVFGDWLCDMAAADKRLVGITPAMREGSGMVEFERRFPDRYYDVGIAEQHAVTFAGGLACEGLKPVVAIYSTFLQRGYDQLIHDVALQNLPVVFALDRAGLVGADGATHAGAYDIAYLRCIPNMMVMTPSDENECRQLLTTAFHQACPSAVRYPRGSGPGAAIAAELTTVPVGKGVMRREGGARAGHRVGFLAFGSMVHPALGAAEALDAAVADMRFVKPLDVELVKRLAAENDYLVTVEEGSVMGGAGSAVLEALAEAGIDKPVLTLGLPDRFVDHGDPAYLLQQCGLDAAGIERSVRERFGLDQPKVTVASRVA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: MTGA_BDEBA
Sequence: MRSRWQTLRKWIVKAVLLFFVSSLGFVLLYRFVPVPLTPLMVIRSVSSVWGEEFVGIHKDWVPLEEIAPSVQKAVLKAEDYRFFEHNGFDFDAIEKAMKYNKTHKRKKGASTITQQTAKNVFLWPQRDWVRKGLEAYFTILIESTWPKERIMEVYLNVIELGPGVYGVEAASQKYFKRSAKNLNPYQASLIAAVLPNPRRFRIDRPSNYVVGRQRRILNRVAPAIPKAADASLLDFLDLKFDSEEDESAN
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MRAZ_HERAR
Sequence: MFQGASSLNLDAKGRMTIPARHRDALLLQCEGRITLTKHPDGCLLLFPRPVWEMRREEIAKWPISARAWQRIFLGNASDVDFDGAGRILIAPELRTAAGLTRDVMMMGMGGHFEIWDAARLAESESDAIAAGMPDVLNDFSF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: COAD_METBF
Sequence: MPKVAVGGTFQYFHDGHAKLIEKAFEIAEDGKVHIGLTSDEMLSKSHSVDNYEKRRNWLLQYIKEMGIPDDRYEITKLNDPYGPALEEDFDYIIVSPETYPVALKMNRIREEKGKKLLEIVYVEYVMAEDGIPISSTRIAKGEIDRHGRLKKNIKHCNTKN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6502_BACAN
Sequence: MEIHVRNVDPYHLKEIDKRCKEIGKKLGRRYYRWEYINMMFEQHFNQEYSRNKEDKFDEAVSNVSITLDRQSDKLQEYIDATHELVAAMIKLNEE
What are the official names of this protein?
Uncharacterized protein pXO2-04/BXB0002/GBAA_pXO2_0002.