PharMolix/UniProtQA huggingface dataset:
Protein: SAT2_ORYSJ
Sequence: MTSCGCLVLEKVEDHGGEAAGRGRGRLAQGGGGGGGGCGSCAGEWRSRSETMFPIYVMGSSRASSAAAARGIVDAAGDPIWEAVKSEAKSEAEKEPILSSFLYASVLSHDCLERALSFVLANRLEDPTLLATQLIDIFNDVMMNNKDIRRSIRLDAQAFKDRDPACAQYSWALLYLKGYHSVQSYRIAHVLWNQGRKVLALALQSRISEVFAVDIHPAARIGEGILLDHGTGLVIGETAIVGNWVSLMQGVTLGGTGKENGDRHPKIGQGALLGAGATILGNINVGEGAMIAAGSLVLKDVPPHSMAVGNPAKVVGYKDKEDPSLTMKHDARRDYFEHVAVSFSDDKANGSVVK
What are the official names of this protein?
Probable serine acetyltransferase 2, OsSERAT3;1.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: ILVC_SYNR3
Sequence: MATLYYDTDADLGLLSGKTVAIIGYGSQGHAHALNLKDSGVDVVVGLYEGSRSADKAKADGLEVLSVADAAAKADWIMVLLPDEFQKEVYDKEIAPHLSAGKVLSFAHGFNIRFGLIKPPADVDVVMIAPKGPGHTVRWEYQNAQGVPALFAIEQDASGNARGLAMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLCGGLSELVKAGFETLVEAGYQPELAYFECLHEVKLIVDLMVKGGLSAMRDSISNTAEYGDYVSGPRLITAETKAEMKRILGDIQDGTFAKNFVAECEAGKPEMNKIRERDSAHKIEEVGKGLRAMFSWLKAA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: THOC5_DROME
Sequence: METILNTQFDQLQKAIEGIKEAKSKGQSTDEARIATTLMFVALKHANREVKHKIKAGRDKLHLEKCKVDLSRLQLQNLLYEVSHLKKEIVRCQKFKSRDTSLELLSEAEYSSELPDMPNDAEELSSHKQHLHRLDCELRLRKALDKQYSALLSSKQELLQDNLSHAQRYVSFAPALRTLQSATKPLHDALQLSLDVEWKLSAVVKYLPKPLYVLFIVLQSLQRVSEEQSFTAEVVGYESEAQMQELLKEKKCSTLNYRQTKKESGDREKIADKNNLDDSLAPHPLHICLTIGAAGSNQLVLQIRYFDFIKCATVWGQLNCSRNANGQGDTNFVHHLLRHLYPNDLGNELPIPGIQYELRSSDLTAEECVRYLKAKDYGKPFCWLQSMCSIATVNSSMLYKHELNLNKNNKEIIDRIARRLNSWQRLSQQIRGLTFKDIDLYSLQENIYPAGLSCSLVQWTAITHEELHSQISDALNSSSADKGITYNSYRAVIVRGSAKMECFIRIPSNYPLEMPLWILNVHWNGCLTAQNNSAIKMMEFWTNSLQPKHLEPNDCILYAQLFRTIYSFDIFLETEGSMQNTIEYNKEKPYISAFAKRSRSRPYKYIKKGSVYAFKQ
What is the function of this protein?
The THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress.
What are the official names of this protein?
THO complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the THOC5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus membrane. Note=Shuttles between nucleus and cytoplasm.
Protein: RPOA_RHOPB
Sequence: MTIQKNWQELIRPNKLVVTPGSDPTRFATLVAEPLERGFGQTLGNALRRVLLSSLQGAAVQSVHIDGVLHEFSSIAGVREDVTDIVLNIKDISIKMQGEGPKRMVVKKQGPGTVTAGDIQTVGDVVVLNPDLQICTLDEGAEIRMEFTVAGGKGYVAAERNRPEDAPIGLIPVDSLFSPVRKVSYKVENTREGQILDYDKLTMTIETNGAISPDDAVAYAARILQDQLNVFVNFEEPRKEVTQEIIPDLAFNPAFLKKVDELELSVRSANCLKNDNIVYIGDLVQKSEAEMLRTPNFGRKSLNEIKEVLAQMGLHLGMEVPGWPPENIDELAKRFEDHY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: GLNA_THET8
Sequence: MGYTKAEILKALKGENVKFLRLQITDILGVVKNVEVPESQFEKALDGEIMFDGSSIEGFTRIEESDMLLRPDYNTFVILPDLVEDPKRGRVARLICDVYYPDGRPFEGDPRYVLKRQIERLKKLGFDNLYAGPEPEFFLFLRTPEGLPTTETHDRAGYFDLAPIDKGEEARRDMVNALVAMGFEIEAAHHEVAPGQHEIDFKYADALTTADNIATFKWVVKRIALNHGLHATFLPKPIRGINGSGMHTHLSLFKDGENAFYDPNAEYQLSQTALHFIAGLLEHAAGMVAVTNPLVNSYKRLTPGYEAPTNIAWSASNRSAMIRIPARRGVGTRAELRMPDPSCNPYLALAVMAAAGADGIERKLLPPPPIQRNIYQMTVRERRKHKIRELPGTLREALEALRKDPVIREALGEHVYTHFLQAKQMEWDDYRVTVHQWELDRYLATY
What is the function of this protein?
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_CROS8
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAVRGMVNAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RL24_CHLL3
Sequence: MKTGLKRVKLHVKKNDMVVVLSGNDRGKSGKVLRVYPVKNRVIIEGVNIRKRHMRPTQSNPQGSIIEREFPIHASNVKKS
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: GSKIP_BOVIN
Sequence: METDCNPMELSGVSGFEEEAELNGFEGTDMKDMRLEAEAVVNDVLFAVNTMFVSKTLRCADDVAYINVETRERNRYCLELTEAGLRVVGYAFDQVDDHLQTPYHETVYSLLDTLSPAYREAFGNALLQRLEALKREGQS
What is the function of this protein?
A-kinase anchoring protein for GSK3B and PKA that regulates or facilitates their kinase activity towards their targets.  The ternary complex enhances Wnt-induced signaling by facilitating the GSK3B- and PKA-induced phosphorylation of beta-catenin leading to beta-catenin degradation and stabilization respectively.  Upon cAMP activation, the ternary complex contributes to neuroprotection against oxidative stress-induced apoptosis by facilitating the PKA-induced phosphorylation of DML1 and PKA-induced inactivation of GSK3B.  During neurite outgrowth promotes neuron proliferation; while increases beta-catenin-induced transcriptional activity through GSK3B kinase activity inhibition, reduces N-cadherin level to promote cell cycle progression (By similarity).  May play a role in cleft palate formation and is required for postnatal life through modulation of the activity of GSK3B during development (By similarity).
What are the official names of this protein?
GSK3B-interacting protein, GSKIP.
What is the protein family that this protein belongs to?
Belongs to the GSKIP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VSR7_ARATH
Sequence: MGLVNGRASLTFLLAALTIIAMVVEARFVVEKESISVLNPEEMRSKHDGSIANFGLPDYGGFLIGSVVYPDSKTDGCSAFGKTFKPKFPRPTILLLDRGGCYFALKAWHAQQAGAAAVLVADNVDEPLLTMDSPEESKDADGFIEKLTIPSVLIDKSFGDDLRQGFQKGKNIVIKLDWRESVPHPDKRVEYELWTNSNDECGARCDEQMDFVKNFKGHAQILEKGGYTAFTPHYITWFCPFQFINSPHCKSQCINHGRYCAPDPEDNFREGYEGKDVVLENLRQLCVHRVANESSRPWVWWDYVTDFHSRCSMKEKKYSIDCAESVIKSLNLPIEKIKKCIGDPEADTENQVLRTEQVSQIGRGNRGDVTILPTLVINNAQYRGRLERTAVLKAICAGFNETSEPAICLNTGLETNECLENNGGCWQDTKANITACQDTFRGRLCECPVVKGVQYKGDGYTSCTPYGPARCTMNNGGCWSDTRNGLTFSACSDSVSTGCKCPEGFQGDGLTCEDINECKERSVCQCSGCRCKNSWGGYKCSCSGDRLYINDQDTCIERYGSKTAWWLTFLILAIVAVAGLAGYIFYKYRFRSYMDSEIMTIMSQYMPLESQRAREVPSEAEPFTL
What is the function of this protein?
Vacuolar-sorting receptor (VSR) involved in clathrin-coated vesicles sorting from Golgi apparatus to vacuoles.
What are the official names of this protein?
Vacuolar-sorting receptor 7, AtVSR7, BP80-like protein f, AtBP80f, Epidermal growth factor receptor-like protein 3, AtELP3.
What is the protein family that this protein belongs to?
Belongs to the VSR (BP-80) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane.
Protein: RL3_BARHE
Sequence: MRSGVIAQKLGMTRIYNDAGEHVPVTVLRLENCQVVAQRTVEKNGYTAVQLGVGFAKVKNTSQALRGHFAKASVEPKAKIAEFRVSPDNLLDIGTEITAEHFVPGQRVDVTGTTIGKGFAGVMKRHNFGGHRASHGNSITHRAHGSTGQCQDPGKVFKGKKMAGHMGQVRVTTQNIEVVSTDVERGLILVRGAVSGSKGAWILVRDAIKKPLPDNAPKPAGIRQLAKEKTEMVAPVTETSEVEGAE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y752_CALS4
Sequence: MKTPRPYLEHILQECEFLIERVKGISFEDFVKDPVLTRAFVRSLEIIGEAVKNLPKEFREKHSKVPWKEIAGMRDKLIHEYFGVNYRIIWETILKEIPELEKQVKEILQKEK
What is the function of this protein?
Probable toxic component of a putative type VII toxin-antitoxin (TA) system, probably an RNase.  Probably neutralized by cognate antitoxin TTE0751.  Neutralization may be due to AMPylation by TTE0751.
What are the official names of this protein?
Putative RNase TTE0752, Putative toxin TTE0752.
What is the protein family that this protein belongs to?
Belongs to the HepT RNase toxin family.
Protein: DER_SHEB2
Sequence: MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAFLSGYEFIVVDTGGIDGTEEGIETKMAEQSLAAIEEADVVLFMTDARAGLTAADLSIAQHLRSREKTTFVVANKVDGIDADSACAEFWSLGLGEVYQMAASQGRGVTNMIEYALTPYAEAMGIVRQGEDEVTEEREYTEEEAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVFDEPGTTRDSIYIPMEREGREYVIIDTAGVRRRSKVHQVIEKFSVIKTLKAVEDANVVLLIIDAREGIAEQDLGLLGFALNAGRALVIAVNKWDGIDQGIKDRVKSELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVIHGNQVSRLPDSYKRYMMNYFRRSLKVVGTPIQLRFQEGDNPFENKTEKLTMSQERRRKRAQSHIKDRKTK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SYFB_BACLD
Sequence: MFVSYKWLQEYVNLDGMTPEILAEKITRSGIEVEGIEYKGEGIKGVVIGHVLEREQHPNADKLNKCLVDIGEEEPVQIICGAPNVDKGQKVAVATVGAVLPGNFKIKKAKLRGEASNGMICSLQELGIQGKLVPKEYAEGIFVFPGDAETGADALQSLALDDAVLELGLTPNRADAMNMLGVAYEVAAILGREVKLPETAYQAGAEKAADYISVKIEDPEANPLYAAKIIKDVKIGPSPLWMQTKLINAGIRPHNNVVDVTNFVLLEYGQPLHAFDYDRFGSKEVVIRKAYENETITTLDEQERTLTTEHLVITNGSSPQAVAGVMGGAESEVREDTATVLLEAAYFNGQTVRKASKDLGLRSESSVRFEKGIDPARVRLAAERAADLISRYAGGTVLEGTVEENHLDIKENVIRLSVDKVTKVLGMSISKEEMVNIFERLGFAVEDAERELVVTVPSRRGDIAIEEDLIEEVARLYGYDNIPSTLPEVTGFAGGLTPYQDKRRKVRRFLEGAGLSQAITYSLTNDKKATAYALEKSFKTILSLPMSEERSVLRHSLLPNLLDSVAYNLARQADSAAFYEIGSVFLKAEEHTKPVEKEHVAGAVTGLWHKNLWQGEKKPVDFFVVKGIVEGLLEKLGITEGIEFAQSERKELHPGRTANILHNGSLVGFIGQLHPSVEKELDLSDTYVFELDLHELLRLDVPEITYTPIPKYPSVTRDIALVVDKQTTAGQLEDVIKTAGGKWLKEVHVFDVYEGEHMEEGKKSVAFSLQYLNPEQTLTEEEVTKVHDQVLKALEDKYQAVLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_THEVB
Sequence: MNAQDIIRSIEAEQMKTDLPVIYVGDRVRVGVKIKEGDKERVQPYEGDVIAMRNTGINRTITVRRVFQGVGVERVFLLHSPRIDSIKVIQRGKVRRAKLYYLRDRMGKASRIKPRFDRPL
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: URE1_BLOPB
Sequence: MLLSKHDYASLFGPTIGDSVRLADTELWIRIEKDFTVYGEEVKFGGGKVIRDGMGQGQMSSKDCVDLVLTNAVILDYWGIIKADIGINNGRISGIGKAGNPDVQPNVTISIGPGTEIIAAEGKIVTAGGIDAHVHFICPQQVEEALCSGITTFIGGGTGPATGSNATTCTPGPWFISRMLQVADTLPINIGVTGKGSASFPDALEEQIIAGAIGLKVHEDWGATPAAIDCCLNVADRFDIQVSMHTDTLNESGFVEDTLSAIKGRTVHAYHTEGAGGGHSPDIIRMCGFSNVLPSSTNPTMPYTVNTIDEHLDMMMICHNLNPNLPEDMAFSESRIRRETIAAEDVLHDLGALSMISSDSQAMGRVGEVILRTWQTAHKMKQQRGSLLGDATRYDDNVRVKRYIAKYTINPAITHGISHEVGSVEIGKLADLVLWSPVFFGVKPELIIKGGMIISSVMGDPNASIPTPQPVHYRLMFGARGKAKHATRMTFLSQVAYNSELTDYLKLVSLIGEVRHCRNIQKKHMINNSWQPVIEVDSQTYQVRANGELLTCEPASVLPMSQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL801_MIMIV
Sequence: MHNKRYNPDVVIDFGVDFSNDYNKSKNKFFDRYIIFNKDFMKYIFKLALRALIMIGIIELSYFISLGGFYLVSNDPIYFRNLSIFHARGVEFATECSDIISIFCSIAFVLFCIYDVGKYYVTKCKSSKRYQ
What are the official names of this protein?
Uncharacterized protein L801.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MSRB_YERPP
Sequence: MAKELNPTENIEKLSDIQRYVTQERGTEAPFTGKLLHNKRDGVYQCLCCHQPLFISESKFDSGCGWPSFYQPIDADSIRYIDDYSHNMHRIEIRCGNCDAHLGHVFPDGPQPTGERYCINSASLNFVDDQNGEQTAG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: BZR4_ORYSJ
Sequence: MMNGGGGGRVPTWRERENNRRRERRRRAIAAKIYAGLRAYGNYTLPKHCDNNEVLKALCNEAGWTVEPDGTTYRKGCKPPASELADQLGRSPSASPCSSYQPSPRGTSSFPSSGSSSQITLGGGGGGEGSSLIPWLKTLSSAGVGIGGGSSSKFPAHYSYFGGGSISAPVTPPSGSPPRTPRLKTAAWEEYHHHHAGSVLPPWATVGASYAYAASSSLPNSTPPSPRRKVAAAAAAAGGGNDAAAWLAGFQISSAGPSSPTYSLVAPPPNPFGAAAAAAGSSSRVMSGACSPVAGGDVQMADAARREFAFGGEGGKMTGLVKAWEGERIHEECGSDDLELTLGSSMTRGDR
What is the function of this protein?
May function in brassinosteroid signaling.
What are the official names of this protein?
Protein BZR1 homolog 4, OsBZR4, Protein BRASSINAZOLE-RESISTANT 1 homolog 4.
What is the protein family that this protein belongs to?
Belongs to the BZR/LAT61 family.
Protein: YQB1_CAEEL
Sequence: MVKSLHYFILPLIGNALILNTPPEYQPGYGYVGPACAVFDSTLFLHGVSKRKLNDHELHIFSSYQHDLSAFKDSSSSFDSFEASFPTIPKFCGGYDDSIEVVLDSCIVRNNHVYVGDHLIRPLTNFEKQKIQLVKMRRMYGESKRKRSKRSSKPLPGTRPQRDFSEMLHKLLNINSTVTSRFLPVVSQSPLFAMEGPWQNLFELGKDKDMIELLAASQFKPQLPPVASVPVAPVIDITKIDSPYRATFTTMKPRKSQKPEKKKEVFNVFTTKTNPQITTTTMTTTTRTSTAIPTTTTTPRQISLQTIPFSTTTRQPNFDKTKTPATMPSASSSSLSSIQTVVDPIILKLISKALEKNEMIDEYSLKQALSMRNVATTTTPLPLRFILPTPAAPNPFLPSTRVGGLSHNHLFIPHQPFTTLVSTDSRYSAPNPLSHRLPNEICRVHMNSNPFHF
What are the official names of this protein?
Uncharacterized protein C30G12.1.
Protein: ASPD2_BORPA
Sequence: MTHRIAFIGLGAIASDVAAGLLADAAQPCQLAALTRNAADLPPALAGRVALLDGLPGLLAWRPDLVVEAAGQQAIAEHAEGCLKAGLDMIICSAGALADDALRARLIAAAEAGGARIRVPAGAIAGLDYLQAVAGRDDAEVVYESRKPVAAWRAELPGMGIDPDTLAESRTLFSGPAREAALRFPKNLNVAATLALAGIGMTRTRVEVVVDPRARGNQHRIQVRSPLGEMQIELVNAPSPANPKTSWLVAQSVLATIRRHLARFTIG
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: NU3M_WHEAT
Sequence: MLEFAPICIYLVISLLVSLILLGVPFLFASNSSTYPEKLSAYECGFDPFGDARSRFDIRFYLVSILFIIFDLEVTFFFPWAVSLNKIDLFGFWSMMAFLLILTIGFLYEWKRGALDWE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CTAA_ANAPZ
Sequence: MRTSHIATWLGTCCIMVLLMVFVGGVTRLTNSGLSITEWRPVTGVLPPISDADWAKEHEKYAKTPEYLYINSGISLSDFKRIYMTEYVHRLLGRILGIIFFVPMLYFAVKRQIKGALAARLGIVALLGALQGAMGWFMVKSGLVDVPYVSHFRLAAHLFLTILLFSLLWHSFLESRGVVAVHKVTHGKYIFAIFMLVITVLQMVLGALVAGLDAGLIFNTFPLMDGDIIPSQILSGELLTGKFLYNAVVVQFLHRFFATVVLVGAVAIPLLMRFKESWMLCFGIVLQFLFGVATLVHGVPLYLASLHQIWSFVVVALEVYILKVIRKV
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHO10_CAEEL
Sequence: MFLSLFCVIIVAVGCSSKDGNVKLEFVQAMWRHGERSALADLYPIYEKDWVFGGGGLGELTGRGMGEMNNLGRLIRERYVRKFNFLEPKYASKEVYFRSTNLNRTIISAMSLLYGLFPPSLYDIPNVDYPFTPLKWLPGLAFVPVHVDGSDQCAASQNCPCPRYDFLQQQMLTLPEVQQAFQQVILLNRQIAPLYNVTTGVDTFYVYPDTWKCQRAYFNKTMYDKLPWYNEQLYSKAEITYAPIKGFLEGSFSQPAVTSNGLDVAFEIQQVRSGVMINEIVSRASEKLNCVERGQNCTSYLNKLKFYGYSIHDNNVYAVLVALGIPHISATEDGWPSYAAAIFFEFYRNSQTNKRLFKVLYRQDASSQITDVTSQVPMCQGVSMCPLSTFQHLADVLKPIPDINTVCNITS
What are the official names of this protein?
Putative acid phosphatase 10.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
Protein: T1R2_METJA
Sequence: MNKMPIPEIYVHNDIEENLNKLGWKELEGYEGEAFSNYIIKPILEEQLKIINDHIGEYKDEFIEKAINKLINEPKPEEILDYIKNGILITLDKGRKGQVSNRVKLIDYKNIEKNIFNYAHELKFKGNDNIIPDFTLFINGIPIIIIEAKREFSEKETYEEAINQINRYEREAPKLFNYVQFAIVYGDEKLYIPTYPNEEKEDRFKKPYKWKNEKKEEDIWDLLKRERVLDTIKNFIFFSKDRAGRKTKIIPRYMQYWAVKKAYERITNYLNNKDYKNRGLVWHWQGSGKTFEILYLAELFYNEFKNKDPIVFIMVDRRELETQFNDDIIALQNANFKDCFKKINSVEELKGVLEDIKESENNPNISEKGVYLVMMHKFDKNKLKDFIESFGSIDKKEILILRDEAHRTESGKFATLRNKILKNAIAIGFTGTPVHKKDMSTFKEYAYPQEGEFYLDRFFIEESIKEGFTLPLIWRVVKPEDIKDISEEEIKNIIEKLFVDEEDADKIVVSKKEIAEKIKLSDLLKSESSIKEASKYIAEHILEDTENFKFKAMVVAQDRKSCILFKKYLDEYLKEKIKNYNENWTQVVITYIHNDDVEIENYKKEIEKKYGKNVDELNKKWTEDFINKENPKILIVNKKLLTGFDAPILKTIYIHQFLKDYLLLQASARANRPAKNKKYGLIVDLTGILIENYKKAIENYNLYRDEAINKDILNNLFVETSKIWESFLTKLNEFKELFKLIVGIEFDDFIVNLKKQKNSKEFKKIISKIILSDKFDYFYAKLRELIQLFEAVGAYGEKLNYYETYEWLKIISAGINKQMRPKSYKIPYNQIKKEVIKYLEFDTYADIASTSINPQLLENLKNKDEINVIVADMIYYALDTLQNKKEPIYRMIYDRINELKNAYISKTKKNEYVINELINCLNALKTYEEEEKTLSKSEKAIKNMLFYLKNVENCNIKKLPLTEKTLKNLEDKKLIKPSDFDKIKKFLFVDLKNAIKETEKRRKVSNKIVEEIIKPIFI
What is the function of this protein?
The restriction (R) subunit of a type I restriction enzyme that recognizes 5'-GAYN(5)GTAA-3' and cleaves a random distance away.  The R subunit is required for both endonuclease and ATPase activities but not for modification.  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage.
What are the official names of this protein?
Putative type I restriction enzyme MjaVIIIP endonuclease subunit, MjaVIIIP, R protein.
What is the protein family that this protein belongs to?
Belongs to the HsdR family.
Protein: WNT1_BOMMO
Sequence: MKCLWLLVITVLCLRCDTAGTKPRRGRGSMWWGIAKAGEPNNLSPVSPGVLFMDPAVHATLRRKQRRLARENPGVLAAVAKAQYAFAECQHQFKYRRWNCSTRNFLRGKNLFGKIVDRGCRETAFIYAITSAGVTHSLARACREASIESCTCDYSHRPRAAQNPVGGRANVRVWKWGGCSDNIGFGFRFSREFVDTGERGKTLREKMNLHNNEAGRRHVQTEMKQECKCHGMSGSCTVKTCWMRLPSFRSVGDSLKDRFDGASRVMLSKADVETPAQRNEAAPHRVPRKDRYRFQLRPHNPDHKSPGVKDLVYLESSPGFCEKNPRLGIPGTHGRACNDTSIGVDGCDLMCCGRGYKTNTMFVVERCNCTFHWCCEVKCKLCRTEKVVHTCL
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.
What are the official names of this protein?
Protein Wnt-1.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: RL27_GRAFK
Sequence: MAHKKGVGSSKNGRESESKRLGVKIFGGQAAIAGNIIVRQRGTAHRPGDNVYAGKDHTLHARVDGLVKFTKKKDDKSYVSIEPFEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RL5_SHEPW
Sequence: MAKLHDKYQETVSPELVKKFGFTSVMQVPRIEKITLNMGVGEAVADKKVMEHALRDMTAIAGQKPVVTVARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGMSVKSFDGRGNYAMGVREQIIFPEIEYDKIDKIRGMDIVITTSAKNDEEGRALLEGFNFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: LSPA_SALTI
Sequence: MSKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSFLADSGSWQRWFFAGIAIGICVILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICIGAALIVLEGFLPKPTAKEQA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYSN_AGRFC
Sequence: MSAAAANTPSSSATILPFAEHSKVARDTRPLRLITCGSVDDGKSTLIGRLLWDTKAVKEDQAATLHRDSGKQNDLGLPDFALLLDGLQAEREQGITIDVAYRYFATDRRAFIVADTPGHEQYTRNMATGASTADLAVLLVDARTGILEQTRRHATIAALMGIRQFVLAVNKIDLTNYDKAGFELIAHEFRDFASDLGIKQITAIPMSALKGENVVLSGKASMPWYEGPTLVETLELATVRSTQSGGFRLPVQRVSRPGESFRGYQGTVAGGSVKPGDSVVVLPSGMVANVKQIVTFDLVRNAAVAGDAVTLVLDRQVDVSRGDMIVSIEAQPLTGLAFDAQIVALQPGGIEAGKRYWLKSASRRQRVSVQPVSQLNLREGEWQAHETSLPMNAIGKVRLSFDETAIFDPYEQNRATGSFILIDPDTNNTVAGGMISAKRSTGATEEQGDRVILSLPAGLAEKLLAGELLAKHRDEIDIRRTDAATASRLIGDLD
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.