PharMolix/UniProtQA huggingface dataset:
Protein: TMED1_HUMAN
Sequence: MMAAGAALALALWLLMPPVEVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT
What is the function of this protein?
Potential role in vesicular protein trafficking, mainly in the early secretory pathway.  May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side.  Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1 (PubMed:23319592).  Also plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26 (PubMed:32614325).
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 1, Interleukin-1 receptor-like 1 ligand, Putative T1/ST2 receptor-binding protein, p24 family protein gamma-1, Tp24, p24gamma1.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
Protein: 3SATF_NAJAT
Sequence: MKTLLLTLVVVTIVCLDLGYTLKCNKLIPIASKTCTAGKNLCYKMFMMSDLTIPVKRGCIDVCPKNSLLVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin I-like T-15, Cardiotoxin I-like T-15.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: DFG10_YEAST
Sequence: MYFDEEQLLKYTIYAYRLSFFVGICSLFIAKSCLPEFLQYGKTYRPKENSKYSSILERIKKFTVPKAYFSHFYYLATFLSLVTLYFYPKFPIVWIIFGHSLRRLYETLYVLHYTSNSRMNWSHYLVGIWFYSVLLLILNISLYKNSIPNTLNMNAFIIFCIASWDQYKNHVILANLVKYSLPTGRLFRLVCCPHYLDEIIIYSTLLPYEQEFYLTLVWVITSLTISALETKNYYRHKFKDNHVAPYAIIPFII
What is the function of this protein?
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol.  Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.  Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.
What are the official names of this protein?
Polyprenol reductase, Protein DFG10.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: G6PD6_ARATH
Sequence: MGSGQWHVEKRSTFRNDSFVREYGIVPETGCLSIIVLGASGDLAKKKTFPALFNLYRQGFLNPDEVHIFGYARTKISDEELRDRIRGYLVDEKNAEQAEALSKFLQLIKYVSGPYDAEEGFQRLDKAISEHEISKNSTEGSSRRLFYLALPPSVYPSVCKMIKTCCMNKSDLGGWTRIVVEKPFGKDLESAEQLSSQIGELFDESQIYRIDHYLGKELVQNMLVLRFANRFFLPLWNRDNIENVQIVFREDFGTEGRGGYFDEYGIIRDIIQNHLLQVLCLVAMEKPISLKPEHIRDEKVKVLQSVVPISDDEVVLGQYEGYRDDDTVPNDSNTPTFATTILRIHNERWEGVPFILKAGKALNSRKAEIRIQFKDVPGDIFRCQKQGRNEFVIRLQPSEAMYMKLTVKQPGLDMNTVQSELDLSYGQRYQGVAIPEAYERLILDTIKGDQQHFVRRDELKVAWEIFTPLLHRIDKGEVKSIPYKPGSRGPKEADQLLEKAGYLQTHGYIWIPPTL
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis (PubMed:15634201).  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division (PubMed:15634201).
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase 6, cytoplasmic, AtG6PD6, G6PDH6.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: XYN2_MAGO7
Sequence: MKASSVLLGLAPLAALAAPTPEAELSARQAQQSIDALMKAKGKLYFGTATDQGLLNTGKNSAIIKADFGQVTPENSMKWQSLENTRGQYNWAPADALVNFAVSNNKSIRGHTLIWHSQLPGWVNNINDRNQLTTVIQNHVATVMGRWKGKIRAWDVVNEIFNEDGTMRQSVFSRVLGEDFVRIAFEAARKADPNAKLYINDYNLDSPNAAKLTKGMVAHVKKWLAAGVPIDGIGSQGHLQSGQGNGLAQAIKALADSGVKEVAVTELDIQGNNANDYAAVTKGCLAVPACVGITAWGVRDNDSWRPQGNPLLFDSNYNPKAAYNSVVQALK
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Accounts for approximately 70 percent of the endoxylanase activity in the culture filtrate (By similarity).
What are the official names of this protein?
Endo-1,4-beta-xylanase 2, Xylanase 2, 1,4-beta-D-xylan xylanohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FER_ARTPT
Sequence: MATYKVTLINEAEGINETIDCDDDTYILDAAEEAGLDLPYSCRAGACSTCAGTITSGTIDQSDQSFLDDDQIEAGYVLTCVAYPTSDCTIKTHQEEGLY
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
Protein: CCA_XANCP
Sequence: MKIYLVGGAVRDALLGQPAGDRDWVVVGADQAQMQALGYKPVGKDFPVFLHPRSGEEYALARTERKSGRGYRGFVVDADPSVTLEEDLLRRDFTINAIARDEASGEVFDPYGGVRDLQQRVLRHVGPAFVEDPVRVLRAARFMARLAPLGFGIAPETAALMREMADSGELDSLVPERVWQELRRVLGSAQPSAFLRTLHDTGALRAILPELDALYGVPQRAEFHPEVDTGVHQEMVSDMAARLAPGDALVGFAALTHDLGKALTPPEQWPRHVMHEQRGVAPLQALCERLKVPQDYRQLAVTACREHLNVHRLPELRDRTVHELLVRCDGFRRPERIAQLALVCEADKRGRLGSEEAAYPQGPELQRVHAAALAINARDLAADGLQGPQIGEALASARIAAIAQARSLRQ
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: MAFA1_NEIMF
Sequence: MKILLLLIPLVLTACGTLTGIPAHGGGKRFAVEQELVAASSRAAVKEMDLSALKGRKAALYVSVMGDQGSGNISGGRYSIDALIRGGYHNNPESATQYSYPAYDTTATTKSDALSSVTTSTSVLNAPAAALTRNSGRKGERSAGLSVNGTGDYRNETLLANPRDVSFLTNLIQTVFYLRGIEVVPPEYADTDVFVTVDVFGTVRSRTELHLYNAETLKAQTKLEYFAVDRDSRKLLIAPKTAAYESQYQEQYALWMGPYSVGKTVKASDRLMVDFSDITPYGDTTAQNRPDFKQNNGKNPDVGNEVIRRRKGG
What are the official names of this protein?
Adhesin MafA 1.
What is the protein family that this protein belongs to?
Belongs to the MafA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SYA_MARMM
Sequence: MASLRDIRATFLDYFAKHEHEVVPSAPLVPQDDPTLLFVNAGMVPFKNSFTGQEKRASLRATSSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEEAISHAWNLVTGEFGLPAEKLLVTVYAEDEQARALWRKIAGLTDDRIIGISTSDNFWSMGDTGPCGPCSEIFFDHGPSIAGGPPGSPDEDGDRFIEIWNLVFMQYEQLGPDERINLPKPSIDTGMGLERISAILQGKHNNYETDLFRNLIAAGESVLGVKAEGDALASHRVIADHLRSTCFLMADGVTPSNEGRGYVLRRIMRRAMRHAHLLGAGEPVMWKLVDALKSEMGDAYPELERAQALLEETLQVEEERFQRTLGRGLSLLEEATADMGEGDALAGATAFKLYDTYGFPLDLTQDALRAKGMTVDEAGFNSAMDKQRADARASKFSSGDAAPDAVWFAVRDKVGATAFTGYAGTGGKGRLTAIVSGGQEAKALGSGQRAELVFDETPFYGESGGQCGDTGEIRFVDGAVFTVEDTQKRGGDMHAHIGVLTKGEITLGDVAALDADAPRRAAIRANHSATHLAHAALRDVLGAHVTQKGSHVGPDRLRFDFSHNKSVSADQIAAIEAQVNAVIRQNVPVSTREMTPDAAIEAGALALFGEKYGDTVRVLAMGQGLADHATPYSVELCGGTHVERTGDIALFKIIAETAVSSGIRRIEAMTGEGARLYMDEQIGFGRAAADALKTPPSDLATRVAALVDERRKLERQLAEAKKQLAMGGGASGAPAGPETINGVNFIGRVVEGVGGKDLRGLIDEAKAQMGSGVAAFIGVNDGKAALAVGVTDDLKDRFVAVDLVKAGAAAVGGKGGGGRPDFAQAGGPDGAKANDGLAAIRAALAG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNAS2_HUMAN
Sequence: MGVWGKKHLRLTHAPSPTFSHLPPSPQAGEPGIDGISLAVVCAAFIRIHPARRHPARNGSRLACTPTPRPNAGLEVVSSARVAASLPSEGGWTSGAPRSSGLSLPGSAWQPPPLPVLRKPAWPGSPAVKNESKFPNRGSRNFPRRRLPPAPVSGEPPERCKLAREIRWRLWKAHEGWGGGAKRPLGDPAWSGVKR
What are the official names of this protein?
Putative uncharacterized protein encoded by ZNF503-AS2, ZNF503 antisense RNA 2.
Protein: DAPE_VEREI
Sequence: MTRTLHLAEQLIARPSITPDDAGCLDLLAARLAPLGFVCERMDSGPARQRVSNLWAKRPVAQVPDAHDASKTAVKTIVFAGHTDVVPTGPLEQWSSNPFLPTRRDGRLYGRGASDMKTSIAAFIVALEEFLAATPEPRIALALLLTSDEEGPSVDGTRVVVEQLKARGDSIDYCIVGEPTAVEKTGDMVKNGRRGTLSGRLLVRGIQGHIAYPQLARNPIHQALPALAELAATEWDQGNEFFPPTSWQISNLHAGTGATNVIPGEMVLDFNFRFSTQSCAEGLQRHVQQLLERHGLSYELHWTLGGQPFLTTPGELLQAVEQAISAETGLSAALSTTGGTSDGRFIAHICPQVIELGPPNASVHKIDEHVLLTDIEALKNIYRRTLENLQAQALAAATMPA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RBL_PAUCH
Sequence: MSKKYDAGVKEYRDTYWTPDYIPLDTDLLACFKCTGQEGVPREEVAAAVAAESSTGTWSTVWSELLTDLEFYKGRCYRIEEVPGDKESFYAFIAYPLDLFEEGSVTNVLTSLVGNVFGFKALRHLRLEDIRFPLAFIKTCGGPPNGIQVERDRMNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDFTKDDENINSQPFQRWQNRFEFVAEAVKTAEQETGERKGHYLNCTANTPEEMYERAEFAKELGQPIIMHDYITGGFTANTGLARWCRKNGILLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDQLRESFVPEDRTRGNFFDQDWASMPGVFAVASGGIHVWHMPALVAIFGDDSVLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILLEAAKHSPELAIALETWKEIKFEFDTVDKLDV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore.
Protein: QUEF_SHEON
Sequence: MTQNHDPYSDAKELAGLTLGKATDYQAEYDASLLQGVPRSLNRNAINLTAESLPFHGADIWTAYELSWLNAKGKPMVAIADIQLSHASQNLIESKSFKLYLNSFNQTKFDNLDAVQKTLVKDLSECAQGDVTVKIIEPKSFGIQRVVELPGTCIDDLDIEVSDYDFNPEYLENSTDEKQIVAETLNSNLLKSNCLITSQPDWGSVMIRYQGPKIDREKLLRYLISFRQHNEFHEQCVERIFVDLKHYCHCAKLTVYARYTRRGGLDINPYRSDFEHPGESHRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1433_SPIOL
Sequence: RNLLSVAYKNVVGARRASWRIISSIEQKEESRGNEDHVSVIRDYRSRIEKELSDNCDGILKLLDTKLVPAASSGDSKVFYLKMKGDYHRYLAEFKTGAQRKEAAESTLTAYKAAQDIANAELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFVEAIAELDTLGEDSYKDSTLIMQLLRDNLTLWTSDMQDEAADEITEEAAKQQKAVNNNKIAY
What are the official names of this protein?
14-3-3-like protein.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: NOP9_ASPNC
Sequence: MPREKVKRGRRATEKANKEASKRKRDDAPEDVVPKRVKPSDDETNDFGAQTGDMPFYGLLDPEEQEYFSRANEVLETNQFGDAEERRVFVESVYKEAEGKELKISCSQSCSRLMEKLISMSDIHQIRRLFSKFIGHFLHLVQHRFASHCCETLFIHAAPGVSQKPSKKASKTEAEEGDEPEPELSLAEMFMKVIEELEGNWGYLLTERFASHTIRVLLLVLAGEPVDLSLSDSVVASRKKERHGVLNEVQDENPVAQKRSVPESFEGTLKKIMQDMVSVLDDTYLRALATHPVGNPVLQVLVYLELSHFGKASAKDPKSIIRRLIPDDTFEEGTESTVFIRGLLYDPVGSRLLETIVRYMPGKLFKGLYKNFLRDQLRSLSRNITAGYVVLKVLERLGKDDLENAVELLVPQIPNLIERSRVIVPKTLVERCIVRGVDTTPIARSLETAYDSDPAKRLSQMLTLEDTTTTSEPQQQNQAQDQDDHQQPPAIPDFGPDNANANINTNPKGAKLHNSLFVQTILTAPGPLSALVYSSLLSQTPESLLTIAKDPTASHVIQKSLTLPTSTPQFRRQFAVRFTGHLEELALDSSGSRVVDALWHATKDVFFVKERMAQELARSEMALRDSFVGRAVWRNWSMDLYKRRRGEWAAKAKGLDVGGEGGQKPKSRIELARERFAAKAAESEKKKNGEDA
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein nop9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NBL1_DANRE
Sequence: MVMCVRAVLVCVLLELSRAAPHAHINRLALFPDKSAWCEAKNITQIVGHTGCTPRSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQTQWEVVTLDCSGSDEAPRVDKLVERILHCSCQSCSKESSQEGALLQLYPHEGAQDLPSLPDATHTHPQHAHMQADQRDADAHLDMHAPEAG
What is the function of this protein?
May act as a tumor suppressor.
What are the official names of this protein?
Neuroblastoma suppressor of tumorigenicity 1.
What is the protein family that this protein belongs to?
Belongs to the DAN family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZEB2_MAIZE
Sequence: MKVLIVALALLALAASAASSTSGGCGCQTPPFHLPPPFYMPPPFYLPPQQQPQPWQYPTQPPQLSPCQQFGSCGVGSVGSPFLGQCVEFLRHQCSPAATPYGSPQCQALQQQCCHQIRQVEPLHRYQATYGVVLQSFLQQQPQGELAALMAAQVAQQLTAMCGLQLQQPGPCPCNAAAGGVYY
What is the function of this protein?
Zeins are major seed storage proteins.
What are the official names of this protein?
16 kDa gamma-zein, 16 kDa zein, Zein Zc1, Zein-2, Zein-gamma.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Note=Endosperm protein bodies.
Protein: MUTL_HAEIN
Sequence: MPIKILSPQLANQIAAGEVVERPASVVKELVENSLDAGANKIQIDIENGGANLIRIRDNGCGIPKEELSLALARHATSKIADLDDLEAILSLGFRGEALASISSVSRLTLTSRTEEQTEAWQVYAQGRDMETTIKPASHPVGTTVEVANLFFNTPARRKFLRTDKTEFSHIDEVIRRIALTKFNTAFTLTHNGKIIRQYRPAEAINQQLKRVAAICGDDFVKNALRIEWKHDDLHLSGWVATPNFSRTQNDLSYCYINGRMVRDKVISHAIRQAYAQYLPTDAYPAFVLFIDLNPHDVDVNVHPTKHEVRFHQQRLIHDFIYEGISHALNNQEQINWHTDQSAVENHEENTVREPQPNYSIRPNRATAGQNSFAPQYHEKPQQNQPHFSNTPMFPNHVSTGYRDYRSDAPSKTEQRLYAELLRTLPPTAQKDISDTAQQNISDTAKIISTEIIECSSHLRALSLIENRALLLQQNQDFFLLSLEKLQRLQWQLALKQIQIEQQALLIPIVFRLTESQFQAWQQYSDDFKKIGFEFIENQAQLRLTLNKVPSALRTQNLQKCVMAMLTRDENSSSFLTALCAQLECKTFNALADALNLLSETERLLTQTNRTAFTQLLKPVNWQPLLDEI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: NCCX_ALCXX
Sequence: MMKSRTFRLSVSTLVGALVGVLMAIVGVYVTHSTEEPHTSLHEMLHDAVPLDSNEREILELKEEEFTARRREIESRLRAANGKLAESIAKNPQWSPEVEEATREVERAAADLQRATLVHVFEMRAGLKPEHRAAYDRVLVDALKRGSQ
What is the function of this protein?
Component of the NCC cation-efflux system that confers resistance to nickel, cobalt and cadmium.  May be involved in the regulation of NCC.
What are the official names of this protein?
Nickel-cobalt-cadmium resistance protein NccX.
What is the protein family that this protein belongs to?
To A.eutrophus CnrR.
Protein: ACTP_ECOHS
Sequence: MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UGT1_USTMA
Sequence: MATEHILLVCWPAVGHARPMLDYAAAQLKQNPGLIITFICSKMQIALLEGLAISEHLADKKFGDRLRLLGTGRPAQEVLKEFGDREDAKNAANSASKAPNTTANGPEPEVILTMQAATLIQKRFAEIFPTILANDDLFDEQDNSLLLPACVAGKPTTIVVNWMLPGMVETVRKHSSDLKMVTFFDNSCTFVTRMLGPRSIGGFGGIERLWSQYCNSNPEVDPNDSTLKEKLLGRRWTGKFYIPGSRMGAIEEQEMAALAKDWLLSVPLTPSLIEIQKLVDASHTILINTHLAVEERELDYLRMVYPFKKIGILGPAMFSGFVEKGEKLAAKLLDKHINVKPAASRPLTPPETPPPGSPDTDSHGEEEDPKQKSVKQVEKFLAESATGSVVYISFGTMFRPQPTHLIKMLEIIIYEMSLSSQFRLLFTFGGSKDLASSCPPSFAPQISALESQLFKSGNTLFVNWVDQHYVLQHPSVGWFLSHGGWNSCQESMLAGTPLLILPFFGDQLFNAYFLESIQIAYRFNTAANMSVADFVASFREGITCTRPESERGSQLTKNAKELQLRLKGERALAEVRLF
What is the function of this protein?
Glycosyltransferase; part of the gene cluster that mediates the biosynthesis of the glycolipid biosurfactant ustilagic acid (UA) (PubMed:15932999, PubMed:17850255).  UA is a secreted cellobiose glycolipid that is toxic for many microorganisms and confers biocontrol activity to U. maydis (PubMed:15932999, PubMed:17850255).  UA consists of 15,16-dihydroxypalmitic or 2,15,16-trihydroxypalmitic acid, which is O-glycosidically linked to cellobiose at its terminal hydroxyl group (PubMed:17850255).  In addition, the cellobiose moiety is acetylated and acylated with a short-chain hydroxy fatty acid (PubMed:17850255).  UA biosynthesis starts with omega-hydroxylation of palmitic acid catalyzed by the cytochrome P450 monooxygenase cyp1 (PubMed:17850255).  Terminal hydroxylation of palmitic acid precedes subterminal hydroxylation catalyzed by the cytochrome P450 monooxygenase cyp2 (PubMed:17850255).  Sequential glucosylation of the hydroxy fatty acid is probably catalyzed by the glycosyltransferase ugt1 (Probable).  The cellobiose lipid is further decorated by acetylation of the proximal glucose residue and by acylation with a short-chain beta-hydroxy fatty acid at the distal glucose residue (Probable).  The acyltransferase uat1 may be a good candidate for catalyzing either acetylation or acylation of the cellobiose lipid (Probable).  The fatty acid synthase fas2 may be involved in synthesis of the carbon backbone of the short-chain beta-hydroxy fatty acid esterified to the cellobiose disaccharide (Probable).  The secreted UA consists of a mixture of both alpha-hydroxylated and non-hydroxylated glycolipids; therefore, alpha-hydroxylation of the long-chain fatty, catalyzed by the fatty acid hydroxylase ahd1, occurs late in UA biosynthesis and may be the last step before secretion (PubMed:17850255).
What are the official names of this protein?
Glycosyltransferase ugt1, Ustilagic acid biosynthesis cluster protein ugt1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: CYOE2_VIBPA
Sequence: MLKSYLSITKPGIIFGNLISVAAGFFLAAKSEPASLMLFLTTLAGVGLVIASGCVVNNIFDRDIDQKMARTQNRETVKGNINIDVAFVYALAMLLLGTALLFQLVNPLSAVVVLLGYVYYVFFYTMWYKRNSVYGTLVGSISGAVPPLVGYLAVTNFISLEAILLFTMFCLWQMPHSYAIAMFRMQDYREAGIPVLPVKDGIHKAHRHMKAYVVAFGAVSLGLFLLGEAGYEYLAVAAVVCLMWTKVTFRSIDESNYVVWSKSVFKVSLLVVMGISGVLGVELIPLAL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPE_BUCAP
Sequence: MINTWPSPAKINLFLYVTGIRSDGYHYIQSLFQFLNYGDTLTIIPNTKGTIELFTESNSLVNIKNSIITAAELLKEKALHSLGKKTSHFGAKIFLNKKIPIGSGLGGGSSNAATTLVVLNNLWKTKFTLQELAELSLKIGSDIPAFIMGKTTIVEGIGEILYPIHRKEKWYLIVYPNISISTKNIFSIYSIKKNTIKKPIDFLLRSRFHNDFENVIKKKFKKIKQLISMLSLYAPSRITGTGSCIFAEFNDKKSAQKIHSLLPHNVQGTIVKSVNVSPLHHAFYKKNINLFN
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: KEFB_SHIFL
Sequence: MLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGFAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKIGMKVLEFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMAPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Putative glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCF3_ANGEV
Sequence: MPRSQRNDNFIDKTFTIVADILLRVIPTTQREKEAFTYYRDGMSAQSEGEYAEALQNYYKAMRLEIDPYDRSYILYNIGLIHTSNGEHAKALEYYSQALERNPSLPQAFNNMAVICHYRGEQAIQQGDPETSEAWFDQAAEYWKQAIALAPSNYIEAQNWLKITGRLKEWV
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.