PharMolix/UniProtQA huggingface dataset:
Protein: DER_STRP2
Sequence: MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: MRAY_LEPCP
Sequence: MLVSLANWLQGHYPDSFGFLRVVQYLTFRAVMSAMTALLLGLVFGPWVIRRLTELKIGQPVREYGVQSHLVKTGTPTMGGVLILLSIAVSTLLWFDWSNRFVWVVMLVTFGFGAIGWVDDWRKVVQKNPEGMASGEKYLWQSLIGLVAAIYLAFSVSETSNLRVLELFLRWVGSGFSNDLPPKADLIVPFFKSVSYPLGVFGFIFLTYFVIVGASNAVNLTDGLDGLAIMPVVLVGSALGLFAYVTGNSVFSKYLLLPHIPGAGELLIFCAAMAGAGLAFLWFNAYPAQVFMGDVGALALGGALGTIAVIVRQEIVLGIMGGIFVVEALSVMAQVAYFKYTKKRYGQGRRILLMAPLHHHYEKKGWEETQVVVRFWIITMLLCLVGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM6_NITEC
Sequence: MDFAQVKDYLVNLQNNIVAGLEQADGGSFRRDSWDRPEGGGGTSCVIEEGNVLERGGVNFSHVHGKGLPASATAARPELAGRAFEAAGVSLVLHPRNPYAPTVHMNVRFFAAIKEGAEPVWWFGGGMDLTPYYGFEEDAIHFHQICKHALQPSGSEYYPRFKKWCDEYFYLKHRKEPRGIGGVFFDDLNQPDFVTCFNLTKSVGDQFLAAYVPILQKRCNLPYGERERDFQAYRRGRYVEFNLVWDRGTLFGLQSGGRTESILMSLPPIVKWRYDWSPAAGSPEAKLYTDFLIGKDWLPLD
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PME_DAUCA
Sequence: QSSTVTPNVVVAADGSGDYKTVSEAVAAAPEDSKTRYVIRIKAGVYRENVDVPKKKKNIMFLGDGRTSTIITASKNVQDGSTTFNSATVAAVGAGFLARDITFQNTAGAAKHQAVALRVGSDLSAFYRCDILAYQDSLYVHSNRQFFINCFIAGTVDFIFGNAAVVLQDCDIHARRPGSGQKNMVTAQGRTDPNQNTGIVIQKSRIGATSDLQPVQSSFPTYLGRPWKEYSRTVVMQSSITNVINPAGWFPWDGNFALDTLYYGEYQNTGAGAATSGRVTWKGFKVITSSTEAQGFTPGSFIAGGSWLKATTFPFSLGL
What is the function of this protein?
Catalyzes the deesterification of methyl-esterified D-galactosiduronic acid units in pectic compounds.  It participates in modulating cell wall during fruit ripening, cell wall extension during pollen germination, and in defense mechanisms against pathogens.
What are the official names of this protein?
Pectinesterase, PE, Pectin methylesterase.
What is the protein family that this protein belongs to?
Belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RSMJ_FRAP2
Sequence: MNVYDLAVISHIENITDIEFEYILSSQDDKYLYVDNNILKLHYKDKELFIDFNSSEILNRINPSTKKCSVVQAVEGRSKDKLNILDTTAGLGRDTFTLAARGHRLVSLEKDCYIFVLLADTLNRARQIPNLKDIANQIELINIDANEYINTASISFDCIYIDPMFPQRNKSAKVKQGMQVLHDIAFNDDESNSNLLKNIIISKKTKKAVVKRPINADFLYGKKPTSQLKGKTNRFDVYSL
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_NITHX
Sequence: MNSSALPHVTIFTDGACSGNPGPGGWGAILRFGEIEKELKGGEPHTTNNRMELLAAISALEALKKAASVDLTTDSQYVRQGITSWIHNWKRNGWRTADKKPVKNADLWQRLDTALQPHQVRWHWIKGHAGHDENERADQLAREGVALARLK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBE2S_DICDI
Sequence: MSSENLPPDVIKRVVKELKELNSSTLEGITLLPCEEDITNIEAVVTGPAGTPYEGGYFKARLILSSDFPRSPPKANFITKIFHPNVSKKGEICVNTLKKDWTEDLGLKHILLTIKCLLIVPNAESSLNEDASRLLLENYDDYCKHAKLFTSIHASKPIIDSNNNNENSTTTPTTTTTATTPSTNTASISSPVKKKTETTNSTTTKVQPKKSLKRL
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.  Acts by specifically elongating polyubiquitin chains initiated by the E2 enzyme ubch10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 S, E2 ubiquitin-conjugating enzyme S, Ubiquitin carrier protein S, Ubiquitin-protein ligase S.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: Y640_MYCPN
Sequence: MKLKLLLIPLLGSSLLLSACSSATSQVISSLSSAQKYFEANKGELNKKNVINILKDGYNSDPNKTVNALLAGWKYTLMDQKLLERNLDASRFASAFGSTSKKDDITPNISEKSLFLADTFPGISSEIAKVFKVEKQTVSGFSYSWNSPKKFQVNIQIKMDGKIDESSKALIKSFLEGNSSGGKGSNGKNSIDESEYTGEKAKFTGNFIFTYTPPTGGARNFSDKSFDVPTSSINFPANVKIDVTTSHTKLNELLESNEQVKKMKSRQLTGKLFNLLPFFTTLCFNSFSPFTVFAVIFTIV
What are the official names of this protein?
Uncharacterized lipoprotein MG439 homolog 5.
What is the protein family that this protein belongs to?
Belongs to the MG439/MG440 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL16_PROMM
Sequence: MLSPKRVKFRKQQRGRMRGVATRGNTIAFGEFALQAQECGWITSRQIEASRRAMTRYVKRGGKIWIRIFPDKPVTMRPAETRMGSGKGNPEFWVAVIKPGRILFEMGGAEITEDIAKEAMRLAQYKLPIKTKFIGLDDQEKVAGSDKPASVPAITAES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RECX_MYCS2
Sequence: MTSSRPRLTSEPSDVPDGEQAQDPRTREEQAKNVCLRLLTVRARTRAELETQLTKRGYPDDVSARVLDRLTEVGLIDDEDFAEQWVRSRHLNAGKGKRALAVELRKKGVDDEVISSALADLDPAAERQRAEQLVRDKLRRERLDGTPENDVKVTRRLVGMLARRGYNQSMAYDVVSVELANERERRRV
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VGF_MOUSE
Sequence: MKTFTLPASVLFCFLLLIQGLGAAPPGRPDVFPPPLSSEHNGQVAEDAVSRPKDDGVPEVRAARNPEPQDQGELFQGVDPRALASVLLQALDRPASPPSVPGGSQQGTPEEAAEALLTESVRSQTHSLPAPEIQAPAVAPPRPQTQDRDPEEDDRSEELEALASLLQELRDFSPSNAKRQQETAAAETETRTHTLTRVNLESPGPERVWRASWGEFQARVPERAPLPPPVPSQFQARMSESAPLPETHQFGEGVSSPKTHLGETLTPLSKAYQSLGGPFPKVRRLEGSFLGGSEAGERLLQQGLAQVEAGRRQAEATRQAAAQEERLADLASDLLLQYLLQGGARQRDLGGRELQETQQERENEREEEAEQERRGGGEDDVGEEDEEAAEAEAEAEEAERARQNALLFAEEEDGEAGAEDKRSQEEAPGHRRKDAEGAEEGGEEDDDDEEMDPQTIDSLIELSTKLHLPADDVVSIIEEVEEKRKRKKNAPPEPVPPPRAAPAPTHVRSPQPPPPAPARDELPDWNEVLPPWDREEDEVFPPGPYHPFPNYIRPRTLQPPASSRRRHFHHALPPARHHPDLEAQARRAQEEADAEERRLQEQEELENYIEHVLLHRP
What is the function of this protein?
Plays a role in the regulation of memory formation and depression-related behaviors potentially by influencing synaptic plasticity and neurogenesis.  Induces acute and transient activation of the NTRK2/TRKB receptor and subsequent CREB phosphorylation (PubMed:26180209, PubMed:30504797).  Induces also insulin secretion in insulinoma cells by increasing intracellular calcium mobilization (PubMed:25917832).
What are the official names of this protein?
Neurosecretory protein VGF.
What are the subcellular locations of this protein?
[Neurosecretory protein VGF]: Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus.
Protein: THI22_YEAST
Sequence: MVIILLGLCTLGFPRTAFCPSIMTNSTVSINTPPPYLTLACNEKLPTVMSIAGSDSSGGAGVEADIKTITAHRCYAMTCVTTLTAQTPVKVYGAQNIPKKMVSQILDANLQDMKCNVIKTGMLTVDAIEVLHEKLLQLGENRPKLVIDPVLCAASDSSPTGKDVVSLIIEKISPFADILTPNISDCFMLLGENREVSKLQDVLEIAKDLSRITNCSNILVKGGHIPCDDGKEKHITDVLYLGAEQKFITFKGQFVNTTRTHGAGCTLASAIASNLARGYSLSQSVYGGIEYVQNAIAIGCDVTKKAVKVGPINHVYAVEIPLEKMLTDECFTASDAVPKKPIEGSLDKIPGGSFFNYLINHPKVKPHWDAYVNHEFVKRVADGTLERKKFQFFIEQDYLYLIDYVRVCCVTGSKSPTLEDLEKDLVIADCARNELNEHERRLREEFGVKDPDYLQKIKRGPALRAYCRYLIDISRRGNWQEIVVALNPCLMGYVYAVDKVKDKITAAEGSIYSEWCDTCASSFCYQAVLEGERLMNHILETYPPDQLDSLVTIFARGCELETNFWTAAMEYE
What is the function of this protein?
Is not required for thiamine biosynthesis.
What are the official names of this protein?
Thiamine biosynthesis protein THI22.
What is the protein family that this protein belongs to?
Belongs to the thiaminase-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: COTB_BACSU
Sequence: MSKRRMKYHSNNEISYYNFLHSMKDKIVTVYRGGPESKKGKLTAVKSDYIALQAEKKIIYYQLEHVKSITEDTNNSTTTIETEEMLDADDFHSLIGHLINQSVQFNQGGPESKKGRLVWLGDDYAALNTNEDGVVYFNIHHIKSISKHEPDLKIEEQTPVGVLEADDLSEVFKSLTHKWVSINRGGPEAIEGILVDNADGHYTIVKNQEVLRIYPFHIKSISLGPKGSYKKEDQKNEQNQEDNNDKDSNSFISSKSYSSSKSSKRSLKSSDDQSSKSGRSSRSKSSSKSSKRSLKSSDYQSSKSGRSSRSKSSSKSSKRSLKSSDYQSSKSSKRSPRSSDYQSSRSPGYSSSIKSSGKQKEDYSYETIVRTIDYHWKRKF
What are the official names of this protein?
Spore coat protein B.
Protein: PRA19_HUMAN
Sequence: MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRCCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFISDGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA
What are the official names of this protein?
PRAME family member 19.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
Protein: CRCH_SYNWW
Sequence: MAYENIILEKEEKLAVLYINRPKAMNALNKDTLLEIKDAVTAVNDDPAVELLIITGSGDKSFVAGADIAFMQNLSAMEAREFGALGQKVFRLIEAMEKPVIAAVNGFALGGGCELAMCCDFRIAASNAKFGQPEVGLGITPGFGGTQRLPRLVGPGMAKQLLYTADVINADEAFRIGLVNKVVQPEELLPEVKKIAGRILSKGQLAVRLSKAAANEGMQTDIDRAMSIEADAFGLCFATQDQKEGMTAFLEKRKANFISK
What is the function of this protein?
Involved in syntrophic growth of S. wolfei with butyrate, as part of the butyrate oxidation pathway.  Probably catalyzes the hydration of crotonyl-CoA to 3-hydroxybutyryl-CoA.
What are the official names of this protein?
Crotonyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_RHOPS
Sequence: MRTATIKRKTKETDIEVTVNLDGAGVSNAATGIGFFDHMLDLLAKHSRIDITVKAVGDLHVDFHHTTEDVGIALGQAVKQALGNMAGINRYASMLMPMDETLTRVVIDVSGRPFLVFKADFPRDKIGEFDTELVREWFQAFAMNAGVTLHVETLYGENSHHIAESCFKGLARALRAAVAIDPQAAGEVPSTKGQLGG
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAS_ECOLI
Sequence: MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQVYTYPAP
What are the official names of this protein?
Protein tas.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: CP2C3_RABIT
Sequence: MDLLIILGICLSCVVLLSLWKKTHGKGKLPPGPTPLPVVGNLLQLETKDINKSLSMLAKEYGSIFTLYFGMKPAVVLYGYEGVIEALIDRGEEFSGRGIFPVFDRVTKGLGIVFSSGEKWKETRRFSLTVLRNLGMGKKTIEERIQEEALCLIQALRKTNASPCDPTFLLFCVPCNVICSVIFQNRFDYDDEKFKTLIKYFHENFELLGTPWIQLYNIFPILHYLPGSHRQLFKNIDGQIKFILEKVQEHQESLDSNNPRDFVDHFLIKMEKEKHKKQSEFTMDNLITTIWDVFSAGTDTTSNTLKFALLLLLKHPEITAKVQEEIEHVIGRHRSPCMQDRTRMPYTDAVMHEIQRYVDLVPTSLPHAVTQDIEFNGYLIPKGTDIIPSLTSVLYDDKEFPNPEKFDPGHFLDESGNFKKSDYFMPFSAGKRACVGEGLARMELFLLLTTILQHFTLKPLVDPKDIDPTPVENGFVSVPPSYELCFVPV
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2C3, CYPIIC3, Cytochrome P450 PBc3, Cytochrome P450 form 3B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: RLME_SYNFM
Sequence: MSYTVRDHYFHKAKKEHYLARAVYKLQEIQDRYKILKPGNRVLDLGAAPGSWMQFAREIVGPSGLVVGVDLKGVEHRFPEGVVVLQGDVTDPELARSLSVEHGPFDVVLSDMAPSTSGIRVADSARSALLFESALEMARSALRPGGHFVAKLFQGAEFHVLLQAVKRDFEWVKVTKPDASRKQSKEIYVIGMRLRKS
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_SHIDS
Sequence: MARVKRGVIARTRHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RSMG_HAEI8
Sequence: MKAKLVSLLAQANIKISDQQIQQLINLVNLLNKWNKAYNLTSVRDPQEMLVKHILDSLVVSPYLQGDRFIDVGTGPGLPGLPLAIINPSKQFVLLDSLGKRISFIRNAIRELRLTNVTPVLSRVEEYQPEDKFDGVLSRAFASLKDMTDWCHHLPKENGYFYALKGIYQEDEINELNKKYTIQKVIELSVPELIGERHLIVLR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICP55_ARATH
Sequence: MQFLARNLVRRVSRTQVVSRNAYSTQTVRDIGQPTPASHPHLMAEGEVTPGIRIEEYIGRRKKLVELLPENSLAIISSAPVKMMTDVVPYTFRQDADYLYLTGCQQPGGVAVLSDERGLCMFMPESTPKDIAWEGEVAGVDAASEVFKADQAYPISKLPEILSDMIRHSSKVFHNVQSASQRYTNLDDFQNSASLGKVKTLSSLTHELRLIKSPAELKLMRESASIACQGLLKTMLHSKGFPDEGILSAQVEYECRVRGAQRMAFNPVVGGGSNASVIHYSRNDQRIKDGDLVLMDMGCELHGYVSDLTRTWPPCGKFSSVQEELYDLILQTNKECIKQCKPGTTIRQLNTYSTELLCDGLMKMGILKSRRLYHQLNPTSIGHYLGMDVHDSSAVGYDRPLQPGFVITIEPGVYIPSSFDCPERFQGIGIRIEDDVLITETGYEVLTGSMPKEIKHIETLLNNHCHDNSARTSPVSLCKVKGLHTNRNPRRLF
What is the function of this protein?
Aminopeptidase which cleaves preprotein intermediates that carry destabilizing N-ter amino acid residues after the mitochondrial processing peptidase (MPP) cleavage site and is thus critical for stabilization of the mitochondrial proteome.
What are the official names of this protein?
Intermediate cleaving peptidase 55, mitochondrial, AtICP55, Protein INTERMEDIATE CLEAVAGE PEPTIDASE 55.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.
Protein: MED7_CRYNB
Sequence: MSSLPQEAALPITNTLFPPPPPYFQAFTDEAIERYETLTGKSLFVNDEKGKTKGKEKKSDDRDMSVDIRIQDLTEEEQNEKLELEGKLEKPRADWVNEDGRWMCFGTMYTTEPIIPTAQSIGLPPFIDPAVEPQESLPPLLHSFLHTLLLLLDTLTMTARTPNELAAAGWASEGDQYIQHLTNLSANMMVASNQLRSAQSEATLVLLMEKELEERRKQTEKLRSKCKEIASGIRALKGL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABR_ECOUT
Sequence: MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTTIIPGNVKDE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_PROMM
Sequence: MSRVCQLTGTRANNGMAVSHSHIRTKKLQQANLQQRRLWWAEGNRWLKLRVSTRALKTIQKKGLGVYAKSLGIDLNKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RS11_CORDI
Sequence: MPPKTRSTARRSGRRVVKKNVAQGHAYIKSTFNNTIVSITDPSGAVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAMDHGMKKVDVFVKGPGSGRETAIRSLQAAGLEVTSISDVTPQPFNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: EFP_VIBC1
Sequence: MATVSTNEFKGGLKLMLDNEPCVILENEYVKPGKGQAFNRVKIRKLLSGKVLEKTFKSGDTCEVADVMDIDLDYLYSDGEFYHFMNNETFEQIAADAKAVGDNAKWLVENNTCMITLWNGNPITVTPPNFVELEVTDTDPGLKGDTQGTGGKPATLSTGAVVRVPLFIAIGEVIKVDTRTAEYVGRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_GRAFK
Sequence: MAYLFTSESVSEGHPDKIADQISDALLDNFLAFDGESKVACETMVTTGQVVLAGEVRSNTYLDVQNIARDVINDIGYTKGAYKFSGDSCGVISLIHEQSQDIYQGVDRGNKEEQGAGDQGMMFGYATNETENYMPLALDISHKILIELAKLRREGKEIEYLRPDSKSQVTIEYSDENVPERIVAIVVSTQHDDFDADDEKMLTKIKKDIIEILIPRVKKQLPEYVQKLFNDDIVYHINPTGKFVIGGPHGDAGLTGRKIIVDTYGGKGAHGGGAFSGKDPSKVDRSAAYASRHIAKNLVAAGVAPEILVQVSYAIGVVEPTSISVYTYGKNNTDLSDGQIAEKVKEIFDMRPSSIEDRLKLRNPIYRETAAYGHMGKEPRKVTKIFESPYKGKITREVELFTWEKLDYVDKVKDAFELN
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D3_RFVKA
Sequence: MNTTILIHDDDIQVNDLKENKTFLLLSEHNERIIDKLCSCLLPIIFYCDYITSPDDEGTLETRILSSSYMIRDKYVNVEEFITAGLPLSWCVNLPEKAHSTASDSLIIRDVLYYKKDWIRILLIQCPSAIYTDEELLIDPFKLPRHPPELFKNVTLRSYVNGLLFYPTSSPLYALLSHVVTTFIIKHITCVTKHDEKLITTCYDKGRFNAFVYAWYNSQISDDVVENEKVKNLFALVKARI
What is the function of this protein?
Late protein which is part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions (By similarity).
What are the official names of this protein?
Core protein D3 homolog, 27 kDa virion core protein.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae D3 family.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: OBG_LEPBA
Sequence: MSGFIDEVPIQIRAGHGGAGSVHFHKEKFVEFGGPDGGDGGKGGDVIFLAEGRMMTLENYLPDRMYAAQDGEPGLGQNRNGKNGEDLILKVPVGTQIIDSVTMELIYDFNHDGESFTIATGGRGGKGNTFFKTSVQQAPRYSQPGEEGGAFSLILELKLLADIGIVGLPNAGKSTLLAKITHAHPKIAGYAFTTLSPNLGVVHRHEDLFRYTVADIPGIIEGASRGVGLGISFLKHIERVQGILFLFDGGNLQLEEELEMLRSELGNYNQTLLDKKFLLVINKMDIWDNDPSFTEEIQKKYSHLGEIICISADKEFNLEYLLERIDKVFFTEKVKLVYENT
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STOA_BACSU
Sequence: MLTKRLLTIYIMLLGLIAWFPGAAQAEEKQPAVPAVFLMKTIEGEDISIPNKGQKTILHFWTSWCPPCKKELPQFQSFYDAHPSDSVKLVTVNLVNSEQNQQVVEDFIKANKLTFPIVLDSKGELMKEYHIITIPTSFLLNEKGEIEKTKIGPMTAEQLKEWTEE
What is the function of this protein?
Thiol-disulfide oxidoreductase with a reductive function, involved in spore cortex synthesis.  It could be involved either in breaking disulfide bonds in cortex components or in proteins that are important for cortex synthesis, or in thiol/disulfide bond interchange.
What are the official names of this protein?
Sporulation thiol-disulfide oxidoreductase A, Stage IV sporulation protein H.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Spore outer membrane.