PharMolix/UniProtQA huggingface dataset:
Protein: YGZB_BACSU
Sequence: MAKYSSKINKIRTFALSLVFVGFIIMYIGIFFKESVLLSSLFMILGLLSIGLSTVVYFWIGMLSTKAVRVICPGCDKETKVLGVVDMCMHCREPLTLDKGLEGKEFDESYNKKKMSK
What are the official names of this protein?
UPF0295 protein YgzB.
What is the protein family that this protein belongs to?
Belongs to the UPF0295 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RAPZ_SALTY
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADRQISAAVSIDVRNMPESPEIFEQAMNNLPGAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKT
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: TRXB_STAAS
Sequence: MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OHK2_ORYSJ
Sequence: MREVEEVSKWRRRCCYFWILFPLAVIATCMTITVVTFCSSTMYMTEVMGEATKGAMDSALMHIAGNMRPLLEANRSVFTIANTLHVQGNMASFSHVGPKLFLAFSMQPLQAQISYAAVDGAAFAYYRAGGGDGEARAMFARPNGTWFTQAVDPATGRPVGNATAAAPHQQLPPNVTRLLLDGGGGGASLADGWARPGVRMLFLSAPVGGGGGAVSAAVAVDDVVLRGAAGLRQLRDLGMYYAVAGNGGATAAPPAPEPAAYRSLLGDGAAAEEMALFSSVKCTASAIDAPPKLDVHGVKSDKYRFACTNFDISGVQMGFRVVLRKSAMVGVFRRGGVTMVAVACAAAAAATVACVLMARALRRAVAREAALGADLARHRDALRQAERKSMNKSNAFASASHDIRSALAAVAGLVEVSRPEANPNIVDNLNQMELCTNKLLDILNSILDTTKVESGKVQLEEVEFNMADVLEESVDMANVVGITKGIEVIWDPCDFSVMKCDNIIGDSKRFKQILDNLLGNAMKFTQEGHVILRAWANRPIARGSIGAPSRFAYRSLENNFFSFFFGAKEDRVSQNSFNPLQNDPNSVEFYFEVVDTGIGIPKEKRESVFENYVQVKEGHGGTGLGLGIVQSFVRLMGGEISIKEKEPGERGTCFGFNVLLKTSGNQAAEEDIEEGPSTVSELDIRASVFRETNCFKGWHCILFVHGDETRRVLQAWMESIGMKVWMVPGVESISSTLEKARSSRDDCDVDRCFSSKEMVSQVLPTTLRNNNIMARNLGEHHPLGMLLIVDVSNGQLENIQRQARDFTQMRSQVPCKFVCLTDLRTSYKDFRRFEEMSCDLILRKPVHGSRLYSLLMTLRDVQSSPMHRSSLVGHENYVTRHQDSANIVALAEVGRLDQGLKTEEDRPLDGMHVLLVEDTLVLQTIQRKMLNQLGAIVELAGDGAKAVDMFRDAIERASVSEEHSVPLPYDVIFMDCQMPRMDGYEATRRIREEESRYGIRTPIIALTAHSMEDDLQKAIDVGMDLHMTKPIERRRIVEAVHGVCKGKN
What is the function of this protein?
Cytokinin receptor related to bacterial two-component regulators.  Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade.
What are the official names of this protein?
Probable histidine kinase 2, OsHK2.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FGF10_RAT
Sequence: MWKWILTHCASAFPHLPGCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSSSSSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation.  Required for normal branching morphogenesis.  May play a role in wound healing.
What are the official names of this protein?
Fibroblast growth factor 10, FGF-10.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y561_HAEIN
Sequence: MYLGLKVGVTFASSIPAAVISMAVLKFFKDSSILENNMVQTQASSAGTLSSVIFVLPGLLMMGYWQDFPFWQTMLICAAGGTLGVLFTIPLRRAMVVNSNLPYPEGVAAAEILKAGNHADGDSGVKDIAYGGVLAGLVAFLTNGLRVMADGASAWIQTGKAAFQLPMGFSLALLGAGYLIGIVGGIAMLIGVILTWGVAVPYFTMSEDIAADASLIDSAMTVWKTKVRYIGVGTIGIAAIWTLLILMKPMIEGMVHSFRMLKGGQEASEHRIDIDLSPKTMIYILIATVALIVISLHHFIAAAPISPELSILLVVVCTFLAVFIGFFVAAASGYMAGLVGSSSSPISGIGIISVIVISLVLVSIGNASGLFETVDGQKFLTALTLFTASIVITTACISNDNLQDLKTGLLVEATPWRQQVALIIGCFVGALVIAPVLEILYHAYGFSGALPRPDMDPSQALSAPQATLMTAISQGIFTNKLEWTYILTGVGLGAVLITIDAFLKKVSNKVFSLPVIAVGIGIYLPPSINTPVIVGAFLAWIMARHIAKLGNKEVSAKAERFGTLFSAGLIVGESLMGVILAFIIAASVTTGGSEAPLSLNLENWDTIGEWFGLIVFIVGIVIFASRVLRAKKI
What are the official names of this protein?
Putative oligopeptide transporter HI_0561.
What is the protein family that this protein belongs to?
Belongs to the oligopeptide OPT transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SECR_MOUSE
Sequence: MEPPLPTPMLLLLLLLLSSSAALPAPPRTPRHSDGMFTSELSRLQDSARLQRLLQGLVGKRSEQDTENIPENSLARSKPLEDQLCLLWSNTQTLQDWLLPRLSLDGSLSLWLPPGPRSAVDRSEWTETTRPPR
What is the function of this protein?
Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis (PubMed:20578263, PubMed:20739612, PubMed:20927047, PubMed:30449620).  Exerts its biological effects by binding to secretin receptor (SCTR), a G-protein coupled receptor expressed in the basolateral domain of several cells (PubMed:30449620).  Acts as a key gastrointestinal hormone by regulating the pH of the duodenal content (PubMed:20578263).  Secreted by S cells of the duodenum in the crypts of Lieberkuehn and regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (PubMed:20578263).  Production of bicarbonate is essential to neutralize the pH and ensure no damage is done to the small intestine by the gastric acid (PubMed:20578263).  In addition to regulating the pH of the duodenal content, plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis, which consequentially induces satiation (PubMed:30449620).  Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain and promotes satiation (PubMed:30449620).  Also able to stimulate lipolysis in white adipocytes (PubMed:24273196).  Also plays an important role in cellular osmoregulation: released into the systemic circulation in response to hyperosmolality and acts at different levels in the hypothalamus, pituitary and kidney to regulate water homeostasis (PubMed:20739612).  Also plays a role in the central nervous system, possibly by acting as a neuropeptide hormone: required for hippocampal synaptic function and neural progenitor cells maintenance (PubMed:18534766, PubMed:21159798).
What are the official names of this protein?
Secretin.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAA2_HAHCH
Sequence: MSDNKALPPAILLMGPTASGKTDLAMALSERLPCDLISVDSVMVYRGMDIGSAKPDPDTLTRYPHHLIDIRDPAEPYSAAEFRTDALRLMEQSVNAGRIPLLVGGTIMYYKALCQGLGDMPSADENVRGQILAEAEQVGWPALHEQLRQVDPVAAAKIHPNNRQRIQRALEVYRLTGKPLSHYWAADGANPENELNWDSVNGAALPYNALNLALAPVKREDLHARIAKRFQIMLEQGMIDEVEQLRRRGDLNVELPSIRAVGYRQVWSYLEGEFGREEMVEKATAATRQLAKRQMTWLRSWPEINWLSADDTQLVEAAMRLISQRLQSCNPL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 2, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 2, DMAPP:tRNA dimethylallyltransferase 2, DMATase 2, Isopentenyl-diphosphate:tRNA isopentenyltransferase 2, IPP transferase 2, IPPT 2, IPTase 2.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL29_AZOVD
Sequence: MKASELREKTAEQLNEQLLGLLRDQFNLRMQKATGQLGQTHLLSQVKRDIARVKTVLNQQAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PQQD_PSEPF
Sequence: MSFDRSKTPTWRPGYRFQYEPAQKGHVLLYPEGMIKLNESAALIGGLIDGERDVAAIIAELDKQFPGVPELGDDIEQFMEVARAQHWITLD
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.
Protein: EFTU_FRUSA
Sequence: DLLSEYGYDLMDTVDEYIPTPERDERKPFMMPIEDVFTITGRGTVASGRIERGVIKLGDEVEIVGLVEDVLKTTVTGIEMFRKTLDEGQAGDNIGALLRGVNREQVVRGQVLAAPGSVQTHEKFSAEVYIMSKEEGGRHTPFFSNYR
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_RUEPO
Sequence: MSRQNYIFTSESVSEGHPDKVCDRISDAVLDAFLTEEPEARVACETFATTNRVVIGGEVGLSDQAKLREYMGRIDQIARDCIKDIGYEQDKFHHETVEITNLLHEQSAHIAQGVNAAEGKDEGAGDQGIMFGYATTETPALMPAPIQYSHAILRRLAEVRKNGTEPALGPDAKSQLSVIYRDGMPVGVSSLVLSTQHLDPDLTSADIRAIVEPYIREVLPEGWLSADTVWHVNPTGKFVIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNVVAAGLADKCTIQLSYAIGVSKPLSIYADTHGTGDIAPAAIEKAIDTVMDLTPRGIRTHLGLNKPIYERTAAYGHFGREPEADGGFSWERTDLAEALKKAV
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP4F3_HUMAN
Sequence: MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFLGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
What is the function of this protein?
Catalyzes predominantly the oxidation of the terminal carbon (omega-oxidation) of polyunsaturated fatty acids (PUFAs) (PubMed:11461919, PubMed:16820285, PubMed:18577768).  Participates in the conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), a signaling molecule acting both as vasoconstrictive and natriuretic with overall effect on arterial blood pressure (PubMed:11461919, PubMed:16820285, PubMed:18577768).  Has high omega-hydroxylase activity toward other PUFAs, including eicosatrienoic acid (ETA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (PubMed:16820285, PubMed:18577768).  Can also catalyze the oxidation of the penultimate carbon (omega-1 oxidation) of PUFAs with lower efficiency (PubMed:18577768).  Contributes to the degradation of saturated very long-chain fatty acids (VLCFAs) such as docosanoic acid and hexacosanoic acid, by catalyzing successive omega-oxidations to the corresponding dicarboxylic acids, thereby initiating chain shortening (PubMed:16547005, PubMed:18182499).  Omega-hydroxylates long-chain 3-hydroxy fatty acids, likely initiating the oxidative conversion to the corresponding 3-hydroxydicarboxylic fatty acids (PubMed:18065749).  Has omega-hydroxylase activity toward long-chain fatty acid epoxides with preference for 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate (EET) and 9,10-epoxyoctadecanoate (PubMed:15145985).
What are the official names of this protein?
Cytochrome P450 4F3, 20-hydroxyeicosatetraenoic acid synthase, 20-HETE synthase, CYPIVF3, Cytochrome P450-LTB-omega, Docosahexaenoic acid omega-hydroxylase CYP4F3, Leukotriene-B(4) 20-monooxygenase 2, Leukotriene-B(4) omega-hydroxylase 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: ATPB_HYANO
Sequence: MRINPTTSGSAVSTLEEKNLGRIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVGQQINVICEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAALSVPVGGATLGRIFNVLGEPIDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLSAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDSLPEQAFYLVGNIDEATAKAMNLEGEKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MTND1_NOCFA
Sequence: MTLVQVMAQDDRDQVVLRTADRTEIADTLRPFGIQLDRWPLRELPADAGQDAVLAAYRAEVDEVCRAGGYRFVDVVRLVPAPEDPEWPARAAAARGRFLDEHRHTEHEVRFFVEGRGCFYLHLGDKVYALVCEAGDLVSVPAGTTHWFDMGAQPHFCAIRFFEREDGWIGDFTGSPIASTMPTLDELVG
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase 1, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1, DHK-MTPene dioxygenase 1, Acireductone dioxygenase (Fe(2+)-requiring) 1, ARD' 1, Fe-ARD 1, Acireductone dioxygenase (Ni(2+)-requiring) 1, ARD 1, Ni-ARD 1.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: PSBC_MESVI
Sequence: MKTLYSLRRFYHVETLFNGTLSISGRDQESTGFAWWSGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFTPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGVYHSLIGPETLEESFPFFGYVWKDKNKMTTILGIHLIVLGVGAYLLVWKACYFGGVYDTWAPGGGDVRIITDPTLSPAVIFGYLLKSPFGGEGWICSVDNMEDVIGGHIWIGNLLIFGGIWHILTKPWAWARRAFVWSGEAYLSYSLGAIATMGWIACCFSWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANIASSQGPTGLGKYLMRSPSGEIIFGGETMRFWDCRAPWIEPLRGPNGLDLNKLKNDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNFVSPRSWLATSHFTLAFFFFVGHLWHAGRARAAAAGFEKGIERETEPVLFMKPLD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GWT1_YARLI
Sequence: MSSQKLLKEEHVSGLTGGSIGEIYVVTCVNLTAYVAWALLRKRYGDHSPWDVDFVIFDFLLNWLGLLLSVTIYSNQPLLLNALIIVPAGVWYIWGRRDRVKKRKELRPDFQQEKDKEVKRADKEMPFLSVYRGSMMVITCIAILAVDFNIFPRRFAKVETWGTSMMDLGVGSFVFSMGVVSKPRTDEPFGPQMKKSLKHAFPVLVLGFIRLISVKSLDYQEHVSEYGVHWNFFFTLGFLPPFVTLVGGLFKKTKIPLMGQSVIIALAYDVLLSVTSLKEYILTAPRVDIFSQNKEGIFSFIGYLAIFLAGQAVGTVILRTKLPEPTPANSKRTPHNLRYRQIIKYLTISSILFHVARLYYDGTIEINVSRRLVNMPYYLWVCAYNTFFLGCYAAIEVILVPIRASQPATPRVPLTLDAVNYNGLVIFLLANIGTGLINMSVNTLEASPAKTMVILVAYCAALSGISLVLYKKEIRLKL
What is the function of this protein?
Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
What are the official names of this protein?
GPI-anchored wall transfer protein 1.
What is the protein family that this protein belongs to?
Belongs to the PIGW family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AQP2_RAT
Sequence: MWELRSIAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGILVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAGQAVTVELFLTMQLVLCIFASTDERRGDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAIIGSLLYNYLLFPSAKSLQERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGSKA
What is the function of this protein?
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient (PubMed:8429910, PubMed:7508187).  Plays an essential role in renal water homeostasis (By similarity).
What are the official names of this protein?
Aquaporin-2, AQP-2, ADH water channel, Aquaporin-CD, AQP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.
Protein: ARBK1_MOUSE
Sequence: MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEAKPLVEFYEEIKKYEKLETEEERVVRSREIFDSYIMKELLACSHPFSKNATEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKRPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIVHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLIQRGSANGL
What is the function of this protein?
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them (By similarity).  Key regulator of LPAR1 signaling (By similarity).  Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor (By similarity).  Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (By similarity).  Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity).  Inhibits relaxation of airway smooth muscle in response to blue light (PubMed:30284927).
What are the official names of this protein?
Beta-adrenergic receptor kinase 1, Beta-ARK-1, G-protein-coupled receptor kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Postsynapse. Presynapse.
Protein: RS101_ARATH
Sequence: MIISENNRREICKYLFKEGVCFAKKDFNLPKHPLIDVPNLQVIKLMQSFKSKEYVRETFAWMHYYWFLTNEGIEFLRTYLNLPSDVVPATLKKSAKPGGRPFGGPPGDRQRGPPRSDGDRPRFGDRDGYRGGPRGGDEKGGAPADFQPSFQGGGGRPGFGRGAGGYSAAAPSGSGFP
What are the official names of this protein?
40S ribosomal protein S10-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BST1_PHANO
Sequence: MVREKAQVTMGSTTMDMLEDEVVKAQDRRWRLRLRNPWACSAYTLVTTALGFAAFFLMLQSFLTKQLDTKGCEMVYMRPMYSKFDDFDTEHTRFASKYSLYLYREWGIDEEFTVKGAPVLFIPGNAGSYKQVRSLAAESAYHYHNSVQHESNAGKGERRPLDFFAVDFNEDFTAFHGQTVLDQAEYLNDAITFILSLYHTPGRSRRDPHLPDPTSVIIVGHSMGGVVARTLFTMPNYQANSINTIVTIAAPHARPPVSFDGDIVRTQNAVNSYWRSAYAQDSAKDNPLQHVTLVSIAGGGLDNIVSSDYASIASIVPETHGFTVFSSSIPNCWTGADHLAITWCDQVRKSIVRALYDVVDVSQAMQTLPVTNRMRFFKKWFLTGLEDIAEKTLPMTTEATLLTVDVDTAILPQEEQLVLRSLGRSSPNIKAFLLPVPPRDRGEKIFTLLTNERLDGPGEHGRLEVLFCSMSSAQSTQSYLTHLDFAGESPTATKLACKNAASDVIILPESTSHSNFPFRPDQAPFSYLQYDVRDLAQHQFVAVLDKVAHHSAGWVVAAFSASSEATVKVNPSLQRLLYTGISLQLPPRRPLTTEISIPALHSSLLAYDVHISRQKCSQGELFAPLLRQYISDLYESKFFVNVEDAMINVHGRGRPTCRAALSSKSPSNGLSLQIWADPTCDSSIDVTLKVDFLGSLGKLWMRYRIVFAAFPLLVVALVLCQQFRTYDATGVFISFAQSLNECMYSSLPLAITALTFLSITLATAQMQSKKLQALGGPASIIGAFFDNDNELLLGSEDPFFWFLVPLFGIMCTAICVMVNYVVLILTYLFATLYALVRSNRLLDASGQRTPDAFAVTSTRRRIINTLILLSLISTAIPYHFAYVVLCIVQLATCIRGFRLAKEAQLDTNYNFYNYAHSIFILMLWILPINLPVLVVWIRNLAIQWLTPFSSHHNVLSITPFILLVETLSTGRMVPRVRPGISLFTNVFLFAIGAYAAVYGVTYAYVLHHLANILCAWLVAIHFDTLGLAFEDSSKGVAVVGGRSEGKKRP
What is the function of this protein?
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
What are the official names of this protein?
GPI inositol-deacylase.
What is the protein family that this protein belongs to?
Belongs to the GPI inositol-deacylase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ALF_SCHMA
Sequence: MSRFQPYLTEAQENDLRRIAQAICAPGKGILAADESTATMGKRLQQIGVENNEENRRLYRQLLFSADHKLAENISGVILFEETLHQKSDDGKTLPTLLAERNIIPGIKVDKGVVPLAGTDNETTTQGLDDLASRCAEYWRLGCRFAKWRCVLKISSHTPSYLAMLENANVLARYASICQQNGLVPIVEPEVLPDGDHDLLTAQRVTEQVLAFVYKALADHHVYLEGTLLKPNMVTAGQACKKAYTPQENALATVRALQRTVPPAVPGITFLSGGQSELDATKNLNEINKIPGPKPWALTFSFGRALQASVLATWKGKKENVHAAQEELLKLAKANGAAAVGKFEGNMGTTLGDKSLFVANHAY
What are the official names of this protein?
Fructose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.