PharMolix/UniProtQA huggingface dataset:
Protein: Y4609_BACTN
Sequence: MISSATKTLQTNNKTIYVAILSTLTFFLFLDYIPGLQAWSAWVTPPVALFLGLIFALTCGQAHPKFNKKTSKYLLQYSVVGLGFGMNLQSALASGKEGMEFTVISVVGTLLIGWFIGRKIFKIDRNTSYLISSGTAICGGSAIAAIGPVLRAKDSEMSVALGTIFILNAIALFIFPAIGHALDMTEHQFGTWAAIAIHDTSSVVGAGAAYGEEALKVATTIKLTRALWIIPMAFATSFIFKSKGQKISIPWFIFFFILAMIANTYLLNGVPQLGAAINGIARKTLTITMFFIGASLSLDVLRSVGVKPLIQGVLLWVVISLSTLAYIYFV
What are the official names of this protein?
UPF0324 membrane protein BT_4609.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VKT4_OXYMI
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPKFCELPADIGPCEDFTGAFHYSPREHECIEFIYGGCEGNANNFNTLEGCESACAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor microlepidin-4.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOA_SODGM
Sequence: MTHRDDLFSAPIASLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAGRFARPGTQIYDLGCALGAATLAMRRTISHGDCRIIAVDNSPAMIDRCRRHISAFHATTPTEIIEDDISTVPIENASLVVLNFTMQFLEPAQRQTLLNRIYAGLNTGGALVLSEKFSFQDQLIGGLLFDMHHDFKRANGYSELEISQKRSMLENVMLTDTVEVHKQRLVEAGFGHAELWFQCFNFGSLISIKPESGQ
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: MDGA1_RAT
Sequence: MEVTCLLLLALIPFHCRGQGVYAPAQAQIVHAGQACVVKEDNISERVYTIRESDTLVLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIRVDVQYLDEPVLTVHQTVSDVRGNFYQEKTVFLRCTVSSNPPARFIWKRGSDTLSHSQDNGVDIYEPLYTQGETKVLKLKNLRPQDYASYTCQVSVRNVCGIPDKSITFQLTNTTAPPTLKLSVNETLVVNPGENVTVQCLLTGGDPLPQLHWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSLKNATFQITPDMIKESENIQLGQDLKLSCHVDAVPQEKVNYQWFKNGKPARTSKRLLVTRNDPELPAVTSSLELIDLHFSDYGTYLCVASFPGSPVPDLSVEVNISSETVPPTISVPKGRAVVTVREGSPAELQCEVRGKPRPPVLWSRVDKEAALLPSGLALEETPDGKLRVERVSREMSGTYRCQTARYNGFNVRAREAQVQLTVHFPPEVEPSSQDVRQALGRPVLLRCSLLRGSPQRIASAVWRFKGQLLPPPPVLPAAAAEGPDHAELRLDALTRDSSGNYECSVSNDVGSATCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVDPVLNYRLSIRQLNQHNAMVKAIPVRRVEKGQLLEYTLTDLRVPHSYEIHLTPYTTFGAGDMASRVIHYTEPINSPSLSDNTCHFEDEKICGYTQDLTDNFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGTLDTHAWSLSGNKGNVWQQAHVPINPSGPFQIIFEGVRGSGYLGDIAIDDVTLKKGECPRRQMDPNKVVVMPGSGAPRLSSLQLWGSMTIFLLALQR
What is the function of this protein?
Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity).  Plays a role in the formation or maintenance of inhibitory synapses.  May function by inhibiting the activity of NLGN2.
What are the official names of this protein?
MAM domain-containing glycosylphosphatidylinositol anchor protein 1, Ig6M.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=Associated with lipid rafts.
Protein: BIOB_MYCMM
Sequence: MTQAATRPSNDAGQDGVTEPDILAVARQQVLERGEGLNQEQVLQVLQLSEDRLEELLALAHDVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFSSPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDARLLSQVAAGIEAIRNEVEINVACSLGMLTAEQVEQLAAMGVHRYNHNLETARSYFTNVVTTHTWEERWQTLTMVRDAGMEVCCGGILGMGETLEQRAEFAANLAELDPDEVPLNFLNPRPGTPFGDLEVLPAGEALKAVGAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLEDLQMPLKALNASL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: PNP_PROM0
Sequence: MEGQNKSITFDGREIRLTTGLYAPQANGSVMIECGDTSLLVTATKTTKKEVSDFLPLICDYEEKLYAAGRIPGGFMRREGRPPERATLISRLIDRPMRPLFPSWMRDEIQIVASCLSLDERVPADILAVTGASIATLLGEIPFYGPMAAVRVGLIGDDFILNPSYREIEKGDLDIVVAGSKEGIVMIEAGANQLSEQDTIEAIDFGYEAVSELIKSQEDLLKDLGIKQVKPSEPEEDKTLPSFLEKNCTKPIELVLKKFDLSKEERDLELEKIKVETQGKIESLKDDNQLKVLLSENDKLLSSDFKKLTKKLMRSQIINDGKRVDGRDLDEVRKISASAGILPKRVHGSALFQRGLTQVLSTTTLGTPSDAQEMDDLNPSTEKTYLHHYNFPPYSVGETRPMRTPGRREIGHGALAERAIIPVLPGKETFPYVLRVVSEVLSSNGSTSMGSVCGSTLSLLDAGVPLKAPVSGTAMGLIKEGKEVRILTDIQGIEDFLGDMDFKVAGTDKGITALQMDMKITGLPVSIISDAIKKARPARLHILEKMQEAIEKPQETLSPHAPRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIEDGGIVTIASHDGAAAEEAQKIIEGLTRKVHEGEIFPGVVTRIIPIGAFVEILPGKEGMVHISQLSEARVERVEDVVRQGDEVTVRVREIDSRGRINLTLRGVGQNGGMSYPEPTPTPVAPLS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y206_LISMC
Sequence: MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
What are the official names of this protein?
UPF0145 protein Lm4b_00206.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: TREF_SALTI
Sequence: MLNQKLNPTPSEDLTIDVDLFYETDPCELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSTKLFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRRFVENHFWLPETLSSEYVSNPENSLKEHIDQLWPILTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLALNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDAGRLASIRTTQFIPIDLNAFLYKLESAIANISALKGERDTEALFRQKASDRRAAVNHYLWDDENGCYRDYDWRREEMALFSAASIVPLYVGMANHEQADRLANVVRSRLLTPGGIMATEYETGEQWDKPNGWAPLQWMAIQGFKRYGDDMLGDEIAHNWLKTVNHFYQEHHKLIEKYHISGGTPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_ORYSI
Sequence: MTIRNQRFSLLKQPIYSTLNQHLIDYPLPSILSYWWGFGSLAGICLVIQIVTGVFLAMNYTPHVDLAFNSVEHIMRDVEGGWLLRYMHANGASMFFIVVYLHIFRGLYYASYSSPREFVWCLGVVIFLLMIVTAFIGYVLPWGQMSFWGATVITSLASAIPVVGDTIVTWLWGGFSVDNATLNRFFSLHYLLPFILVGASLLHLAALHQYGSNNPLGVHSEMDKIAFYPYFYVKDLVGWVAFAIFFSIWIFFAPNVLGHPDNYIPANPMSTPPHIVPEWYFLPIYAILRSIPDKAGGVAAIALVFISLLALPFFKEMYVRSSSFRPIYQGIFWLLLADCLLLGWIGCQPVEAPFVTIGQISSFFFFLFFAITPILGRVGRGIPKYYTDETHRTGSFS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYDP_SALEP
Sequence: MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISSTRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQTWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGTRNRTVLAATLAEFLTQLNPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: ELHC_APLCA
Sequence: ISINQDLKAITDMLLTEQIQARRRCLAALRQRLLDLDSDVSLFNGDLLPNGRCS
What is the function of this protein?
Injected in sexually mature animals califin C excites LB and LC cells of the abdominal ganglion and cause egg-laying.
What are the official names of this protein?
Califin-C.
What is the protein family that this protein belongs to?
Belongs to the molluscan ELH family.
What are the subcellular locations of this protein?
Secreted.
Protein: ESR1_CHICK
Sequence: MTMTLHTKASGVTLLHQIQGTELETLSRPQLKIPLERSLSDMYVESNKTGVFNYPEGATYDFGTTAPVYGSTTLSYAPTSESFGSSSLAGFHSLNNVPPSPVVFLQTAPQLSPFIHHHSQQVPYYLENEQGSFGMREAAPPAFYRPSSDNRRHSIRERMSSTNEKGSLSMESTKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGEMMKQKRQREEQDSRNGEASSTELRAPTLWTSPLVVKHNKKNSPALSLTAEQMVSALLEAEPPIVYSEYDPNRPFNEASMMTLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATAARFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEERDYIHRVLDKITDTLIHLMAKSGLSLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAPAARSAAPMEEENRNQLTTAPASSHSLQSFYINSKEEESMQNTI
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RISC_METTM
Sequence: MIKVGICDTTFARYDMGGAAIDEIKKHATGIKIIRRTVPGIKDLPVACKKLIEEEGCEMVMALGMPGPEEKDKVCAHEASTGLIQAQLMTNTHILEVFVHEDEEDDPEDLKVLADNRAREHAQNLIMMLFRPERLTRDAGMGMREGKPDVGPL
What is the function of this protein?
The relatively low activity of this enzyme suggested that 6,7-dimethyl-8-ribityllumazine might not be its natural substrate.
What are the official names of this protein?
Riboflavin synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ANSP2_MYCTU
Sequence: MPPLDITDERLTREDTGYHKGLHSRQLQMIALGGAIGTGLFLGAGGRLASAGPGLFLVYGICGIFVFLILRALGELVLHRPSSGSFVSYAREFYGEKVAFVAGWMYFLNWAMTGIVDTTAIAHYCHYWRAFQPIPQWTLALIALLVVLSMNLISVRLFGELEFWASLIKVIALVTFLIVGTVFLAGRYKIDGQETGVSLWSSHGGIVPTGLLPIVLVTSGVVFAYAAIELVGIAAGETAEPAKIMPRAINSVVLRIACFYVGSTVLLALLLPYTAYKEHVSPFVTFFSKIGIDAAGSVMNLVVLTAALSSLNAGLYSTGRILRSMAINGSGPRFTAPMSKTGVPYGGILLTAGIGLLGIILNAIKPSQAFEIVLHIAATGVIAAWATIVACQLRLHRMANAGQLQRPKFRMPLSPFSGYLTLAFLAGVLILMYFDEQHGPWMIAATVIGVPALIGGWYLVRNRVTAVAHHAIDHTKSVAVVHSADPI
What is the function of this protein?
Dual function in both nitrogen assimilation and in protection against acid stress during infection (PubMed:24586151).  Involved in asparagine uptake (PubMed:24586151).
What are the official names of this protein?
L-asparagine permease 2, L-asparagine transport protein 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVA_BURMS
Sequence: MIGRIAGTLLEKNPPHILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPPERSTFRELLKITGVGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHATDILNALVALGYSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: UCHL4_MOUSE
Sequence: MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMESELLSIIPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGTIGLIHAIANNKDKVHFESGSTLKKFLEESVSMSPEERAKYLENYDAIRVTHETSAHEGQTEAPSIDEKVDLHFIALVHVDGHLYELDGWKPFPINHGKTSDETLLEDVIKVCKKFMERDPDELRFNAIALSAA
What is the function of this protein?
Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins.  This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase isozyme L4, UCH-L4, Ubiquitin thioesterase L4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_NITHX
Sequence: MVDTKNPGDKTLSVGPSKTLTLKPRVEQGTVRQSFSHGRTKQVVVEKRGKRRIGGDAPAAEPVAASEPTVARAPRIPVRPAPPAASRANSGVVLRTLTEDERTARASALAEAKIRAEEERRIAEAEAARRNSKEGIEQAEREAAEARRKAEEERHRQEEEAKRKAELEAKRRFGESETKAAPAKTTTTTTRAAPPARPAAVAADGSDEEEAPRLVRRPGGGPARPVVAPKPAAKPAPAKQRGRLTLVTALSADDVRERSIASFRRRTQRLKGHASNEPKEKLIREVIVPEAITIQELANRMAERAVDVIRMLMKQGAMHKITDVIDADTAQLIAEELGHTVKRVAASDVEEGLFDADDDSTVVEPRSPVVTVMGHVDHGKTSLLDAVRHANVVSGEAGGITQHIGAYQVTSPDGKKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQTVEAINHAKAAKVPMIIAINKIDKPDAKPERVRTELLQHEVQVESMGGQVIDVEVSAKNKTNLDKLLEMISLQADLLDLKTNASRPAEGTVIEAKLDRGRGPVATVLVQRGTLRVGDIIVAGAEMGRVRALISDQGETVDEAGPSVPVEVLGFNGPPEAGDRLAVVENEARARQVTSYRAHQKRENAAASSSGMRGSLEQMMSQLKTAGRKDFPLVIKADVQGSLEAILGSLEKLGTEEVAARILHAGVGGISESDVTLAEGFNAAIIGFSVRANKEAAAAAKRNGIEIRYYNIIYDLVDDVKKAMSGLLAPTLRETMLGNAEILEVFNISKVGKVAGCRVTDGNVERGANVRLIRENVVVHEGKLSTLKRFKDEVKEVQSGQECGMAFESYHDMRVGDVIECYRVETIQRSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL2_SACS2
Sequence: MNNIAYKWQTRWEEDKIYESNPNPSKPKFFTTVAFPYPNSPWHIGHGRTYVTGDILARYKRMRGYNVLFPMAFHYTGTPIMAMADAIAKGDKELIETFKDIYEISPDVIPRMSDPLFMANYFKEDIKASMREIGLGIDWRREFTTIDPEFSSFVTWQFHKLQSKGYIVKDTHPVGWCPVHHIPVGMHDTKGDVEPEIGEFVLIYFNSEKGIFPAATLRPETIFGATALWINPSEMYVVASMLGKKMILSEKAAAKLSFQIDDIEIEEKIKGSKLVGLKVENPITGKHIAVLGADFVDVSLGTGVVMSVPAHAPFDYYYSKKTFKNNNIEIIPVITVEGLGNALAKDVVEKNNPKSDEDLKKLTEYVYRTEYNKGVLRSDLGNLIREEYRNELKSLGGLPVPKGRELITNFLISKGLGRKIFEVMNKPVYCRCGTEIVVKILKDQWFLDYSNKEWKELARKSLSKINVIPEESRKDFEFTIEWLEKRACARTRGLGTPLPWDKKWIIESLSDSTIYMAYYTISHKIKQYKLSPSKLTQEFWDYVMLGIGNLEEISEKTGIPSNIIKEFREEFLYWYPLDIRHSGKDLIPNHLTFFIFNHAAIFQENLWPKAIAVNGLVLYEGKKMSKSLRNIIPLRKGLKMYGVDVMRIAVSSTADMGSDVNFSESLVKTVGETLRKMYELFKSLDNYTGDILGFPEKWLLSRIYEITSSTTRHMEALELRDAVNELLFVFSSDLDEYFGMVSAEGREANNKVLREVLTIWLKLITPFAPHLAEEIWHEILKQKTYIVNEGWPEVEGSKMDELTLLEHEYMKRIVEDIRSILNIFKGTPKLIKIYALNDSRYMELLRDAIVANGQMKKFMDIHKPKSREDARILQKIFNESLEIDDKMKKLVTNYNINEVDVLNKLSKYIRRKLNVDILIEPYDEEVKKTYNKEAMPLRPAIIIE
What are the official names of this protein?
Leucine--tRNA ligase 2, Leucyl-tRNA synthetase 2, LeuRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEB_YERPP
Sequence: MTHPSFIRLRFAFKLSFAIVAALFLGFHLQLETPRWSVLTAAIVSAGPAFAAGGEPFSGAIRHRGWLRIIGTFIGCIGGLVIIVLTIRAPVLTLMLCCLWAGICTWISSLVRVENSYAFGLAGYTALIIIVTTGETPLLTPQFAVERCSEIVLGIVCAVMADLLFSPRSIKQDIDRLVDKVLVDQYRLLQLCIQPAEKSEIDRAWNELVKNTTSLNGMRSYLMMESSRWQRCNRRLQVLHTESLALITQACETYLVMSNHPEVISAELKTMLSEPAQTPAEIHQQMKKLRQFIAASHSEAIPHTISSWVGAATRYLLLSKGIQTNSSINQVEEDILAGDAPVKPISAEGHHAMINGLRTGIATAIGGLFWLWTGWTSGAGCMVMIAVVTSLAMRTPNPRRMALDFLVGVIIALPIGALYFMFIIPSTQQSMLLLCISLGVLAFIIGIEVQKRRLGSLGTLASTINIIVLSNPMIFNVRQFLDSALGQIVGCFVSLIVLLLIRDNAKDRTGRTLLNRFVYSAVSALTTNKTKRGENHLPALYQQLNQLLMMFPADIDKYRLALTLIIAHQRLNRTEIPVNAELSAFHKQIRSTAERVITVNNDQKRRYYFARLLQELDQYQQKLVDYQAADAVIRPVKRLTEMLRKYQSALI
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OOEP_PAPAN
Sequence: MVDDAGTAESQRGKQTPADSLEQLRMLPLPPPQIRIRPWWFPVQELRDPLVFYLEAWLADELFGPDRAMIPEMEWTSQALMTVDIVDSGNLVEITVFGRPSVQNRVKSMLLCLASFHREHRARAEKMKHLEKNLKAHASDPHSPQDPVA
What is the function of this protein?
As part of the OOEP-KHDC3 scaffold, recruits BLM and TRIM25 to DNA replication forks, thereby promoting the ubiquitination of BLM by TRIM25, enhancing BLM retainment at replication forks and therefore promoting stalled replication fork restart (By similarity).  Positively regulates the homologous recombination-mediated DNA double-strand break (DSB) repair pathway by regulating ATM activation and RAD51 recruitment to DSBs in oocytes (By similarity).  Thereby contributes to oocyte survival and the resumption and completion of meiosis (By similarity).  As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (By similarity).  Required for the formation of F-actin cytoplasmic lattices in oocytes which in turn are responsible for symmetric division of zygotes via the regulation of mitotic spindle formation and positioning (By similarity).
What are the official names of this protein?
Oocyte-expressed protein homolog.
What is the protein family that this protein belongs to?
Belongs to the KHDC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLR25_ARATH
Sequence: MSLFHHLVSRFLSLWLLIFLVFLVLSLGKSQKEALQVKVGIVLGSNVTLADLSLRAINMSLSEFYNTHNGFKTRIVLNVRDSKQTVVGAAASALYLIKKREVVAIIGPGTSMQAPFLINLGNQSKVPIISFSATSPLLDSLRSPYFIRATHDDSSQVQAISAIIESFRWREVVPIYVDNEFGEGILPNLVDAFQEINVRIRYRSAISLHYSDDQIKKELYKLMTMPTRVFIVHMLPDLGSRLFSIAKEIDMLSKGYVWIVTNGIADLMSIMGESSLVNMHGVLGVKTYFAKSKELLHLEARWQKRFGGEELNNFACWAYDAATALAMSVEEIRHVNMSFNTTKEDTSRDDIGTDLDELGVALSGPKLLDALSTVSFKGVAGRFQLKNGKLEATTFKIINIEESGERTVGFWKSKVGLVKSLRVDKVSHSSRRLRPIIWPGDTIFVPKGWEFPTNAKKLRIAVPKKDGFNNFVEVTKDENTNVPTVTGFCIDVFNTVMSQMPYAVSYEYIPFDTPDGKPRGSYDEMVYNVFLGEFDGAVGDTTILANRSHYVDFALPYSETGIVFLVPVKDGKEKGEWVFLKPLTKELWLVTAASFLYIGIMVWIFEYQADEEFREQMIIDKISSVFYFSFSTLFFAHRRPSESFFTRVLVVVWCFVLLILTQSYTATLTSMLTVQELRPTVRHMDDLRKSGVNIGYQTGSFTFERLKQMRFDESRLKTYNSPEEMRELFLHKSSNGGIDAAFDEVAYIKLFMAKYCSEYSIIEPTFKADGFGFAFPLGSPLVSDISRQILNITEGDAMKAIENKWFLGEKHCLDSTTSDSPIQLDHHSFEALFLIVFVVSVILLLLMLASRGYQERQHNASPNLPNDQANAAQEEVNEEGNVGDHIVEVDTALVRRKKLTSNTIPIRRVAPLSRLKSA
What is the function of this protein?
Glutamate-gated receptor that probably acts as non-selective cation channel.  May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.
What are the official names of this protein?
Glutamate receptor 2.5, Ligand-gated ion channel 2.5.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SPVB_SALEN
Sequence: MLILNGFSSATLALITPPFLPKGGKALSQSGPDGLASITLPLPISAERGFAPALALHYSSGGGNGPFGVGWSCATMSIARSTSHGVPQYNDSDEFLGPDGEVLVQTLSTGDAPNPVTCFAYGDVSFPQSYTVTRYQPRTESSFYRLEYWVGNSNGDDFWLLHDSNGILHLLGKTAAARLSDPQAASHTAQWLVEESVTPAGEHIYYSYLAENGDNVDLNGNEAGRDRSAMRYLSKVQYGNATPAADLYLWTSATPAVQWLFTLVFDYGERGVDPQVPPAFTAQNSWLARQDPFSLYNYGFEIRLHRLCRQVLMFHHFPDELGEADTLVSRLLLEYDENPILTQLCAARTLAYEGDGYRRAPVNNMMPPPPPPPMMGGNSSRPKSKWAIVEESKQIQALRYYSAQGYSVINKYLRGDDYPETQAKETLLSRDYLSTNEPSDEEFKNAMSVYINDIAEGLSSLPETDHRVVYRGLKLDKPALSDVLKEYTTIGNIIIDKAFMSTSPDKAWINDTILNIYLEKGHKGRILGDVAHFKGEAEMLFPPNTKLKIESIVNCGSQDFASQLSKLRLSDDATADTNRIKRIINMRVLNS
What is the function of this protein?
Mono-ADP-ribosylates eukaryotic muscle and non-muscle actin on 'Arg-177'.  ADP-ribosylation prevents the polymerization of G-actin to F-actin, causing actin filament depolymerization, destruction of the cytoskeleton and cytotoxicity.  Does not possess NAD(+)-glycohydrolase activity, unlike most mART enzymes (By similarity).
What are the official names of this protein?
Mono(ADP-ribosyl)transferase SpvB, mADPRT, mART, 65 kDa virulence protein, NAD(+)--arginine ADP-ribosyltransferase, Toxin SpvB.
What is the protein family that this protein belongs to?
Belongs to the SpvB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-2 TTSS).
Protein: PYRDB_SYNWW
Sequence: MDLTVNLGGIKLKNPVAVASGTFGYGLEYADFIEPEKIGAVIVKGTTLHPRPGNPGPRIYETPAGMLNAIGLENPGIEVFLREYLPRLRERQVTVIANIAGNSIEEYALMASLLQGQEGIAGIELNISCPNVKQGGIQFGTDPETVRQVVAAVKKETSLPVIPKLSPNVTDIVAIALAAADGGADALSMINTLGGMAININLKKPVLGNIFGGLSGPAIKPVALKMIYQVYREVDLPILGGGGIVNHIDALEFFMAGATAVSIGTGNFVNPCLALELLEGIKKYMQEQGFSSIQELVGIAHA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHK_NOSP7
Sequence: MVLNSNLTTQDKQRIINPIERTNVTQDLSENVILTTVDDLYDWARLSSLWPLLFGTACCFIEFAALIGSRFDFDRFGLIPRSSPRQADLIITAGTITMKMAPQLVRLYEQMPEPKYVIAMGACTITGGMFSVDSPTAVRGVDKLIPVDVYLPGCPPRPEAIIDAIIKLRKKISNESIQERDKIKQTHRYYSTTHNLKPVEEILTGKYLQSDTRSAPPKELAEAIGMPIPPALLTEKAQKEEQTRG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, NAD(P)H dehydrogenase I subunit K, NDH-1 subunit K, NDH-K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.