PharMolix/UniProtQA huggingface dataset:
Protein: RBPJL_HUMAN
Sequence: MDPAGAADPSVPPNPLTHLSLQDRSEMQLQSEADRRSLPGTWTRSSPEHTTILRGGVRRCLQQQCEQTVRILHAKVAQKSYGNEKRFFCPPPCVYLSGPGWRVKPGQDQAHQAGETGPTVCGYMGLDSASGSATETQKLNFEQQPDSREFGCAKTLYISDADKRKHFRLVLRLVLRGGRELGTFHSRLIKVISKPSQKKQSLKNTDLCISSGSKVSLFNRLRSQTVSTRYLSVEDGAFVASARQWAAFTLHLADGHSAQGDFPPREGYVRYGSLVQLVCTVTGITLPPMIIRKVAKQCALLDVDEPISQLHKCAFQFPGSPPGGGGTYLCLATEKVVQFQASPCPKEANRALLNDSSCWTIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDVATLELHGENFHAGLKVWFGDVEAETMYRSPRSLVCVVPDVAAFCSDWRWLRAPITIPMSLVRADGLFYPSAFSFTYTPEYSVRPGHPGVPEPATDADALLESIHQEFTRTNFHLFIQT
What is the function of this protein?
Putative transcription factor, which cooperates with EBNA2 to activate transcription.
What are the official names of this protein?
Recombining binding protein suppressor of hairless-like protein, Transcription factor RBP-L.
What is the protein family that this protein belongs to?
Belongs to the Su(H) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMB_BORBR
Sequence: MASTQVLAGFHAVVARLRHAPESIKEIYVEASRRDKRMQTFLEQAERAGRRVHPVAAERLDGLARGTRHQGVVAVAEERSLAVGIDEVLDVIEGPALLLILDGVTDPHNLGACLRTADAAGVHAVIAPRDRAVGLNATVQRVACGAADTVPYLTVTNLARTMRELKERDVWLVGTDDQAGESMHQVDARRSMAWVMGAEGEGMRRLTRETCDQLVRIPMLGSVESLNVSVASAVCLYESVRQRQG
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_STAAE
Sequence: MLLGSHVSMSGKKMLEGSAIEAHEYGETTFMIYTGAPQNTRRKSIEDLNITKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKGTEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQQFDPELKNKVMQQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: FABA_XANAC
Sequence: MTRQSTYSRDQLLASARGELFAPDSGRLPNDPMLMFDRITEISNTGGAHGKGVIRAELDIRPDLWFFGCHFIGDPVMPGCLGLDAMWQLTGFFLTWIGAPGRGRALGCGEVKFTGQVLPSARLVRYEIDVSRVINRKLVMAQTDARMLVDGREIYTAKDLRVGMFTSTENF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDS1_SCHPO
Sequence: MSSSSVSNTLSIETKSDPKDPAFVASQESTECNEHDTTQLSGSSSEPLENNSSLTRSTDDPSVEIRSKLVSPDNEANLLSDQNITISNENNNENDTTEEAETSSGNEAADDEDSSSDAQSSVPSFSEIHDGMSEEELDKERKTLTHLRRISLQGADDPEIPTDWSVAMSPPETEQDASTLFWVPANLHPELNPTGWKSFLDLQVKNLKSPTATDTSSSPLEHIRSLRRRKSLLSRQVKADDAVINYQDGSPIVEKAYLKRHRSLRLNELEHLESLARDPHRMVSLVDGMSNGSPEDSPLLVSPNHFLQRSSRTTIRRTGASIRTIHRGKTSTLSGNRSHSILQKPTDTSPLHKIEPISADELVESDDSRTSALSNSQNPSDDVENQSDQALEVLSLTNPPKIDNASADTTLHKETNKIDKLYVSENKAESAVASESSLSEGTLALKAPAPENKPEKSSTSKPPVPENKAEDSVVLKSSVPEDKSENSIASKPSATEGIPENAIALQSSVPENKAEDSVVLKSSVPEDKSEDSVPSKSSVLEDKHENSVEIDKKADDSLPSNNKTEGYTPSVVREEKNYSEPNASPSVIPPRVPTPVPGRTLSPKPTRIPTPIPSSLNVSLESSKKPEIFHERHIPTPETGPNKPSKNNILKSTQVPVTPKQKSSTANKGSTSSPSPPSSESKKTKRSWGRLFVSGDSDKEHKEHKKDKQKKKNDQISSSSKSASSFKKDRDKESIFGSLFGSKKKQTEIPPVSSSPPHNDAPPKAKPISAPSELPNTTSVAEAKCQTVTDDEGTDQQSDEKSTEPKTFIPDKDYYWSRFPICTERAIYRLSHIKLSNAHRPLFQQVLLSNFMYSYLDLISRISSNRPMNNVQQSTAKPIRKDINGQQRRSEFSAENVKNELENLSYQFGDQRKRNLNRKGSTIHTVSQNIQKVSKNAK
What is the function of this protein?
Has a role in establishing cell polarity.  Also required for maintenance of cell wall integrity, sexual differentiation, calcium tolerance and cell morphology.  Involved in Ras-MAPK signaling pathway at cell cortex.  Has a role in meiosis.
What are the official names of this protein?
Protein zds1, Meiotically up-regulated gene 88 protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum and cell cortex.
Protein: RPAB1_YEAST
Sequence: MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
What is the function of this protein?
DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  RNA polymerase complexes are composed of mobile elements that move relative to each other.  In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template.  Seems to be the major component in this process.
What are the official names of this protein?
DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerases I, II, and III subunit ABC1, ABC27, DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAND_PARD8
Sequence: MFIEVVKSKIHRVTVTEANLNYIGSITIDEDLLDAANLIANEKVSIVNNNNGERFETYIIKGERGSGVVCLNGAAARKAQPGDIIIVMSYAMMDFEEAKTFKPSVVFPDTATNKLI
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK2_DELRA
Sequence: AGLFAQPRL
What are the official names of this protein?
CAPA-Periviscerokinin-2, CAPA-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLND_MYCTO
Sequence: MEAESPCAASDLAVARRELLSGNHRELDPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSDLDVLLLHDGKPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAALGMLEARHIAGDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHTDLPAGSLDGAYRTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSAGRTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARDAEPEHDPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVDRHVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPVCTRLGLSPPDVRTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVMAGESLPQAEPTAPHYLSLAADHGVHVEISPRDGERIDAVIVAPDERGLVSKAAAVLALNSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSDAASLVSARAGDVQAGVPVTRTAAPPRILWLDTAAPAKLILEVRAMDRAGLLALLAGALEGAGAGIVWAKVNTFGSTAADVFCVTVPAELDARAAVEQHLLEVLGASVDVVVDEPVGD
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory protein (GlnB), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII protein and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII protein, and plays an important role in the regulation of nitrogen assimilation and metabolism (By similarity).
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: RL27_BORGP
Sequence: MATSKSGGSSKNGRDSISKRLGVKRSGGQFVKAEEIIVRQRGTKFHKGRNVGLGRDYTLFALSSGKVEFKTLKGKKYVNII
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CO1A1_SCESX
Sequence: SVPGPMGPSGPRGLPGPPGPGPQGFQGPPGEPGEPGSGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGASGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGPPGPKGNSGEPGAPGKGDTGAKGEPGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGPGFQGLPGPAGPPGEADLGAPGPSGARGERGFPGERGVQGPPGPAGPRGPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGAPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGPPGPIGNVGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKEGGKGPRGETGPAGRPGEVGPPGPPGPGEKGSPGADGPAGAPGTPGPQGISGQRGVVGLPGQRGERGFPGLPGPSGEPGKGPPGPMGPPGLAGPPGEGREGSPGAEGSPGRDGSPGPKGDRGETGPSGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPAGPAGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPAGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: ERPA_CITK8
Sequence: MSDDVALPLQFTEAAAKKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGAVDYTEGLEGSRFVVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PRD15_MOUSE
Sequence: MCPPTIWEKGGQVGARWSLRAPEVSAMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSKDIPAGTELRVWYAAFYAKKMDKPMLKQACSSVQAAGTPEPSVSVEPERGQWVCKVCSNTFLELQLLNEHLLGHLEQAKSLPAGGQQHEAASEKEPDAPRMEPPTAAESKSIQSVMVTKEPKKKPRRGRKPKASKVEQPLVIIKDKEPSEHVAEIITEIPPDEPVSATPDERIMELVLGKLAAPTNEASSVPKFPHHPSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGECAHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTAPSSSVGLTNITVTPITTAAGTQFTNLQPVAVGHLTNPDRQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEATNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAVPQTDVLQPPQAPAAPQQAVQPQVQNEQQQMYSY
What is the function of this protein?
Sequence-specific DNA-binding transcriptional regulator.  Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision.  Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs).  Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions.  Also plays a role in induced pluripotent stem cells (iPSCs) reprogramming.  Involved in early embryo development.
What are the official names of this protein?
PR domain zinc finger protein 15, PR domain-containing protein 15.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYM_XANC8
Sequence: MTRTALVTTALPYANGPLHLGHLVGYIQADIWVRARRLRGDKTWFVCADDTHGTPIMLAAEKAGVTPEAFIANIQASHERDFAAFGVTFDHYDSTNSPVNRELTEAFYTKLEAAGHISRRSVAQFYDPAKGMFLPDRYIKGICPNCGSADQYGDNCEVCGATYAPTELKEPKSVISGATPELRDSEHFFFEVGHFDGFLREWLDGDVALPGVKAKLKEWLDAEGGLRAWDISRDAPYFGFQIPGQPGKYFYVWLDAPIGYLCSFKTLCAQMGEDFQAHLAAGTQTELHHFIGKDIVNFHGLFWPAVLHGTGHRAPTRLHVNGYLMVDGAKMSKSRGTFVMARTFLDVGLEPEALRYYFAAKSSGGVDDLDLNLGDFVARVNADLVGKFVNLASRCAGFIGKRFDGKLADALPDPAQYARFVEALAPIREAYERNDPASAIRQTMALADEANKYIDDTKPWVIAKQEGADAQLQSVCTQGLNLFRLLVAALKPILPRTAAEAEAFLSAPMTSWEDVSRPLTCHVIQPYTALFTRIDPKLIDAMTDASKDTMAAPAAPAATTASAEKVAKIDAKAATPANPPASVANPGLIGMDDFAKLDLRIGKVLVCEAVEGSDKLLRFELDAGELGKRQIFSGIRASYGEPETLVGRSVVFIANLAPRKMRFGISEGMILSAGFDGGALALLDADAGAQPGMPVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOPAD_PSESM
Sequence: MLIGHSLHHMRPTAVDSSLPTSATSQTISNTKSRLDPHRVRELTFIGVGSSVAYLLNELNGRFADSGVTTPFLGKVSIVGKDDSWAENVRGKGYINHQTEIISQWDQQVPKYDPNYAARAEFSASNRRQLTRTVELGAEHLKAQVTGISRLDDGCFRINLDNGQILQSRQIVLGTGAGPHTSIWNSVTSHTQAEKRLDNIKLHEQKALRGKVLDLDEFMRASDASPQTFAGKTVVIHGPNAGIDAAERAGELGANAVWFTRSTNPVLLDGNQLKFAPELAKSAIHKVDKLDIRPTKLENGFALRLHYSSLGQDSREPKKVLDADYYVYAMGQDIHKPGSAAAILGSLLDHLEPIYDYDQVYSDQPFKTVIGLQSRGSNSDNGLIIVGAAVAQLATNVQHSYKDHALDRILEEMTRLPEKQTEKLSQMLLEGAPSVQIQTYLKTWQLDSGQPPDKQVLQNQVENYLAARDYFQRQTNEQKGNLDGVAAEVKNQTLTEVASVIVSPQLGTIKASAAALSGLMPAYVANGENNFTTDNRTMLRAGIAARYPNIGNAEASAFIDEVVTLRHLNSQRFIEKVAGEMMDKGAQPLVSLRPPVLGVPASVRTAYEAYLHALNSGAHDGTPLSQRWLPKK
What are the official names of this protein?
Effector protein hopAD1, Hrp-dependent outer protein I.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system (TTSS).
Protein: PSBF_PROM3
Sequence: MAQSSSAPLQALNVRVYPIFTVRWLAVHVLGVPTVFFLGAITAMQLIRR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: GUAA_TOLAT
Sequence: MSKNIHKHRILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPDGIILSGGPESVTESDSPRAPEYVFNAGVPVLGVCYGMQTMAEQLGGKVESSDKREFGYAKVKLVKDSELFHNIEDAITEDGRPELDVWMSHGDKVMEIPVDFVTIAVTPTCPHAAMANEAKRFYGVQFHPEVTHTVQGARMLERFVKEICHCEALWTPATIIEDAVARIREQVGTDEVILGLSGGVDSSVVAMLIHRAVGKQLTCVFVDNGLLRLNEGQQVMEMFGDHFGLNIIKVDAEERFLSALKGIADPELKRKAIGRVFVEVFDDESKKLKNAKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMKMGLVEPLRELFKDEVRRVGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHNADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGHVSNRIINEINGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DAPD_CITK8
Sequence: MQQLQNVIESAFERRADITPANVDTVTREAVNQVISLLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIDGAESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAFVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CANT1_HUMAN
Sequence: MPVQLSEHPEWNESMHSLRISVGGLPVLASMTKAADPRFRPRWKVILTFFVGAAILWLLCSHRPAPGRPPTHNAHNWRLGQAPANWYNDTYPLSPPQRTPAGIRYRIAVIADLDTESRAQEENTWFSYLKKGYLTLSDSGDKVAVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVVYQIEGSKAVPWVILSDGDGTVEKGFKAEWLAVKDERLYVGGLGKEWTTTTGDVVNENPEWVKVVGYKGSVDHENWVSNYNALRAAAGIQPPGYLIHESACWSDTLQRWFFLPRRASQERYSEKDDERKGANLLLSASPDFGDIAVSHVGAVVPTHGFSSFKFIPNTDDQIIVALKSEEDSGRVASYIMAFTLDGRFLLPETKIGSVKYEGIEFI
What is the function of this protein?
Calcium-dependent nucleotidase with a preference for UDP.  The order of activity with different substrates is UDP > GDP > UTP > GTP.  Has very low activity towards ADP and even lower activity towards ATP.  Does not hydrolyze AMP and GMP (PubMed:12234496, PubMed:15248776, PubMed:15006348, PubMed:16835225).  Involved in proteoglycan synthesis (PubMed:22539336).
What are the official names of this protein?
Soluble calcium-activated nucleotidase 1, SCAN-1, Apyrase homolog, Putative MAPK-activating protein PM09, Putative NF-kappa-B-activating protein 107.
What is the protein family that this protein belongs to?
Belongs to the apyrase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cell membrane. Note=Processed form: Secreted.
Protein: ECPR_ECOLU
Sequence: MTWQNDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKDFVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAGLSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTVYTHRRNAEAKLYSKIYKLVP
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition.  Positively regulates the expression of the ecp operon (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator EcpR.
What is the protein family that this protein belongs to?
Belongs to the EcpR/MatA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE23_HELHE
Sequence: MKLTPKELDKLMLHYAGELAKQRKAKGIKLNYTEAVALISAHVMEEARAGKKSVADLMQEGRTLLKADDVMPGVAHMIHEVGIEAGFPDGTKLVTIHTPVEAGSDKLAPGEVILKNEDITLNAGKHAVQLKVKNKGDRPVQVGSHFHFFEVNKLLDFDREKAYGKRLDIASGTAVRFEPGEEKTVELIDIGGNKRIYGFNALVDRQADHDGKKLALKRAKEKHFGTINCGCDNK
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA1_YERPS
Sequence: MNIDKIFENPSNLRSFEFNNDVCKVFDDMVSRSVPGYHNIQDIISLTYDEFSQNRVFIDVGCSTGTTIAKILSENQVNYCYGIDISESMLAIAQEKCGEHESLVTFKNCNLLNGTDNVINSEKVPDFIILNLVLQFIRPPERKKFITNIKSLCSSSTLMLVFEKIIFNDAEINMKYIDSYLKWKGKNGYSESEVSNKRKALENKLIPYLHEENIELFKSSGFNSVEICFSFLNFRGYLCRC
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase 1, Cx-SAM synthase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: LSR_MOUSE
Sequence: MAPAASACAGAPGSHPATTIFVCLFLIIYCPDRASAIQVTVPDPYHVVILFQPVTLHCTYQMSNTLTAPIVIWKYKSFCRDRVADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFEQTAWGDSGVYYCSVVSAQDLDGNNEAYAELIVLGRTSEAPELLPGFRAGPLEDWLFVVVVCLASLLFFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSIYTHLSPAKTPPPPPAMIPMRPPYGYPGDFDRTSSVGGHSSQVPLLREVDGSVSSEVRSGYRIQANQQDDSMRVLYYMEKELANFDPSRPGPPNGRVERAMSEVTSLHEDDWRSRPSRAPALTPIRDEEWNRHSPRSPRTWEQEPLQEQPRGGWGSGRPRARSVDALDDINRPGSTESGRSSPPSSGRRGRAYAPPRSRSRDDLYDPDDPRDLPHSRDPHYYDDLRSRDPRADPRSRQRSHDPRDAGFRSRDPQYDGRLLEEALKKKGAGERRRVYREEEEEEEEGHYPPAPPPYSETDSQASRERRMKKNLALSRESLVV
What is the function of this protein?
Probable role in the clearance of triglyceride-rich lipoprotein from blood.  Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (PubMed:15265030).  Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (PubMed:21245199, PubMed:23239027).
What are the official names of this protein?
Lipolysis-stimulated lipoprotein receptor, Angulin-3, Lipolysis-stimulated receptor, Liver-specific bHLH-Zip transcription factor, Liver-specific gene on mouse chromosome 7 protein.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. LISCH7 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Located at tricellular contacts.
Protein: ARLY_STRM5
Sequence: MADLLWQKPGVAVDAKIQTFLAGDDVILDREFFLHDIAASAAHAQGLQHIGILSADELAGLLRELDVLAQDFRAGRFVLDTQYEDGHSAIEARLTERLGDAGRKIHTGRSRNDQILVATRLWLKEKLQRVAQLSAEVAKVALDRAQAEKDLPIPGYTHIQRAVVSSAGMWWAGWAEAFIDNAIRARDTHALVDANPLGTAAGYGVNLPLDREHTTAALGFARMQISPIYAQLSRGKFELAALEALGAATLDLRRIAWDLSLFTSAEFGFVALPAQYTTGSSIMPNKRNPDVIELMRATHASVAAARTEIEQLLSLPSGYHRDLQSSKGAIFHGFGRGLAALELLPSLLANLEWRDDKLRAAIDSGMYATDVAVEAAVAGVPFREAYKAAAAGADSAGQGRTPEGSLAARVSPGSAADLRLDELRARWQALS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GG12F_HUMAN
Sequence: MSWRGRSTYYWPRPRRYVQPPEMIGPMRPEQFSDEVEPATPEEGEPATQRQDPAAAQEGEDEGASAGQGPKPEAHSQEQGHPQTGCECEDGPDGQEMDPPNPEEVKTPEEGEKQSQC
What are the official names of this protein?
G antigen 12F, GAGE-12F.
What is the protein family that this protein belongs to?
Belongs to the GAGE family.
Protein: CRCB2_NITHX
Sequence: MNYLLVFVGGGLGATVRHAVNMICARAFGTHFPFGTFLINVSGSVVMGLIAGYLAFRGSAAQPWRLFVMTGVLGGYTTFSAFSLDTALLYERGEIGLAALYAIGSVVLAVVGLFAGLALVRHLT
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.