PharMolix/UniProtQA huggingface dataset:
Protein: DAPA_GEOSM
Sequence: MFQGSIVAIVTPFKNGAVDEEKLRELVEFQIENGTDAIVPCGTTGESSTLSYVEHDRVIQVVVEQVNKRVPVIAGTGSNSTHEAIEITQHAKELGADGALLVTPYYNKPSQEGLFRHYKAVADAVALPQILYNVPGRTGVNLLPETVARLSVHQNIVAIKEATGSLQQASEVLALCGDKIDVLSGDDFITLPIMAAGGKGVISVTANIMPKEVSSLVDAFNAGNLEEARRLHLYLLKISNAMFIESNPVPVKAAVSLMGKCSSEVRLPLAPLMEANLAKLTAIMKEYKLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_RHILO
Sequence: MDRAEKRELVTGLNEAFGNAGSVVVAHYAGITVAQMNDLRSKMRAAGGTVKVAKNRLAKIALQGTDSASIIDLFKGQTLIAYSEDPIAAPKVASDFAKGNDKLVILGGAMGTTSLNADGVKALATLPSLDELRAKLVGMIATPATRIAQIVNAPAASVARVIGAYARKDEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: KI21B_HUMAN
Sequence: MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENGYASTDEEISEFSEGSFSQSFTMKGSTSHDDFKFKSEPKLSAQMKAVSAECLGPPLDISTKNITKSLASLVEIKEDGVGFSVRDPYYRDRVSRTVSLPTRGSTFPRQSRATETSPLTRRKSYDRGQPIRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQSQGSALDKSDDSDSSLSEVLRGIISPVGGAKGARTAPLQCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNNVVSIKYCSHSGLVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVISGDACAATSTRAITSAQGEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQTASQHDLVVTGSKDHYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTPIGEIKGHDSPINAICTNAKHIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRATTLP
What is the function of this protein?
Plus-end directed microtubule-dependent motor protein which displays processive activity.  Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation.  Plays a role in lerning and memory.  Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface.
What are the official names of this protein?
Kinesin-like protein KIF21B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, dendrite. Cell projection, growth cone. Cell projection, axon. Cytoplasmic vesicle.
Protein: RS2_RENSM
Sequence: MPVVTMRQLLNSGVHFGHQTRRWNPKMKRFILTERNGIYIIDLQQSLSYIDRAYEFVKATVAHGGTVLFVGTKKQAQEAIAEQSTRVGQPYVNHRWLGGMLTNFQTVAKRIQRMKELEEINFEDVASSGHTKKELLLLKRELTKLEGNLGGIRNLNKVPSTIWIVDTKKEHLAIDEAKKLNIPVVAILDTNCDPDEVDFPIPGNDDAIRSVNLLTRVIADAVAEGLIARNAKATGSAEGTAAEPLAEWERELLESSNTEAPVAETAAAEAPVADAAIEAPVAEEAKTTEADDTK
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: FDHD_GEOKA
Sequence: MSGFAAKRRPIAKYRNGRFVEEEDEIALEFPLTITVNGEEFATIVCTPAHLDELVIGFLASEGAIRTCSDIKGMTIDGERGFAYVELAAGGLPAKQFYAKRFIGSCCGKSRQFYFYNDMKTAKTIVGGITVKADDCIRLMKALHERSTDFAATGGLHNAALATPDEMVVIRSDIGRHNALDKLYGYCLRHQVAMKDKLIVFSGRVSSEVLLKAAKMGVSVLLSKSAPTTLALDLADELGITVVGFLRGQAFNVYTHESRIIIG
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STC_ONCMY
Sequence: MLAKFGLCAVFLVLGTAATFDTDPEEASPRRARFSSNSPSDVARCLNGALAVGCGTFACLENSTCDTDGMHDICQLFFHTAATFNTQGKTFVKESLRCIANGVTSKVFQTIRRCGVFQRMISEVQEECYSRLDICGVARSNPEAIGEVVQVPAHFPNRYYSTLLQSLLACDEETVAVVRAGLVARLGPDMETLFQLLQNKHCPQGSNQGPNSAPAGWRWPMGSPPSFKIQPSMRGRDPTHLFARKRSVEALEREME
What is the function of this protein?
Its primary function is the prevention of hypercalcemia.  Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment.  STC also stimulates phosphate reabsorption by renal proximal tubules.  The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.
What are the official names of this protein?
Stanniocalcin, STC, Corpuscles of Stannius protein, CS, Hypocalcin, Teleocalcin.
What is the protein family that this protein belongs to?
Belongs to the stanniocalcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTS_HELPJ
Sequence: MSGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEGVVALEVAPDFKSAMMVEINSETDFVAKNEGFKELVKKTLETIKTHNIHTTEELLKSPLDNKPFEEYLHSQIAVIGENILVRKIAHLKAPSSHIINGYAHSNARVGVLIAIEYNNEKNAPKVVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPTFGSRIELSDEVLAHQKKAFEDELKEQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVIADCSKEWDDNLKITEYVRFELGEGIEKKTENFAEEVALQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_POLAQ
Sequence: MSKITALFKELKASGKKGLIPFITAGDPDPKLTVELMHALVRGGSSVIELGVPFSDPMADGPVIQRSSERALTQGVTLHSCLDMVKEFRKKDATTPVVLMGYANPVEQMGAERFATEAKAAGVDGVLIVDYPPEECVDFAARMRVAGIDPIFLLAPTSSHERIKEAAKIASGYIYYVSMRGVTGASHLNTQDVASIIPKIREETDIPIAVGFGINDAASAKAVSVSADAVVIGSRIIRLLEDAPPGQAVQSLETFIREIRDALDS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: PLSY_BARHE
Sequence: MNEGEILFQFTTWLIFLISYLIGSIPFGLLLTKLAKLGDVRTIGSGNIGATNVLRTGNKKVAALTLLCDILKGTLVILVIKFLTDPIENNIFISLAGFFAFLGHLFPVWLKFKGGKGVATYLGVCLGLYWPAAIVFITAWIVLFLITRYSSLSALIAVIITPIFVHFSYPYLYAHCILVIMSLLVMIKHHANIGRLLVGKESKIGTQNGGK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS7_GLAP5
Sequence: MPRRRSIEPRKILPDPKFGSELLAKFINVLMVDGKKSIAESIVYNALETLAQRSGKDALEAFEIALENVRPTVEVKSRRVGGSTYQVPVEVRPTRRNALAMRWIVEAARKRGDKSMAMRLANELSDAADNKGSAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PROBT_OLEEU
Sequence: MSWQTYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVEGLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS15_STRP1
Sequence: MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIKQHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: VLP21_BORHE
Sequence: MRKRISAIINKLNISIMMMIVVLMIGCGQQPEAGKTGAAGGEKQGAGSLSEVLMEVGKSAENAFYSFLELVSDTLGFTAKSTTKKEDVGGYFNSLGGKLGEASNELEQVAKNSEAGIEKNDASKNPIRSAVNAAKKTLEALKGYLDSLGTVGDSNPVGWASNNAQGAAVDEAELKKAYKALKGIMDTAEGAGVARPEVGNIAVKVGNGTDNKDGAKILATDGAAAVGDAGKAAAILTTVSGKEMLASIVNSTEDKAVKITGNVTVETTPLEFAVGGNGAHLSQNANSKAAAVAGGIALRSLVKGGKLAADNNDDDKASQGVGITAANKLLVAVEDIIKKTVKNVLEKAKGEIDKARDPKPAGQQ
What is the function of this protein?
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time.  Switching between these genes is a mechanism of host immune response evasion.
What are the official names of this protein?
Variable large protein 21, Variable major outer membrane lipoprotein 21.
What is the protein family that this protein belongs to?
Belongs to the variable large protein (Vlp) family. Alpha subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SOSD1_CHICK
Sequence: MLLSAIHFYGLLLACTFTRSYSAFKNDATEILYSHVVKPAPASPSSNSTLNQARNGGRHYAGTGSDRNNRVQVGCRELRSTKYISDGQCTSINPLKELVCAGECLPLPLLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSIRTYKITVVTACKCKRYTRQHNESSHNFEGTSQAKPVQHHKERKRASKSSKHSTS
What is the function of this protein?
Can activate or inhibit Wnt signaling in a context-dependent manner.  Activates the canonical Wnt pathway whereby acts through Disheveled proteins and beta-catenin.  Antagonises Wnt signaling through the canonical pathways presumably by blocking accessibility of certain WNTs to their receptors.  Induces posterior neural markers via components of the canonical Wnt pathway.
What are the official names of this protein?
Sclerostin domain-containing protein 1, Wnt-signaling modulator.
What is the protein family that this protein belongs to?
Belongs to the sclerostin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SELO_AROAE
Sequence: MKNLVLDNRFVHELPGDPNPSPDVRQVHGACYSRVMPTPVSAPHLIAWSPEVAALLGFDESDVRSPEFAAVFAGNALMPGMEPYAACYGGHQFGNWAGQLGDGRAITLGEAVTTRGDGHTGRWELQLKGAGPTPYSRHADGRAVLRSSIREFLCSEAMHHLGVPTTRALCLVGTGEKVVRDMFYDGRPKAEPGAVVCRVAPSFIRFGNFEIFTSRGDEALLTRLVDFTIARDFPELGGEPATRRAEWFCKVCERTARMIAQWMRVGFVHGVMNTDNMSILGLTIDYGPYGWIDNFDPGWTPNTTDAGGKRYRFGNQPHIAHWNLLQLANALYPVFGAAEPLHEGLDLYARVFDEENRRMLAAKLGFEAFGDEDATLVETLHALLTRAEVDMTIFFRGLASLDLEAPSIDPLRDAFYSAEKAAVAEPEMNSWLAAYTKRTKQERTPGDQRRVRMNAVNPRFVLRNYLAQEAIDAAEQGEYALVSELLDVMRHPYDEQPGRERFAARRPDWARNRAGCSMLSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: SECB_YERPE
Sequence: MSEQNNTEMAFQIQRIYTKDISFEAPNAPQVFQQDWQPEVKLDLDTASSQLAEDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSVAGIEGTQLAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAEGEVEGVEQRQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE2_HPV10
Sequence: METLANRLDACQDKMLELYEKDSDKLEDQITHWHLLRVENALLYKARECGLTHIGHQVVPPLSVTKAKARNAIEVHVALQQLQESAYAHEPWTLRDTSREMWDTAPKGCWKKRGITVEVRYDGDESKAMCYVQWRELYVQNYSDDRWVKVPGKVSYEGLYYTHENMNIYYVNFKDDACVYGETGKWEVHVGGKVIHHDAFDPVSSTREISTPGPVCTSNTTPASTQAQVGASEGPEQKRQRLEAVDGQHQQQRQGSKDSTQKAAERAGGQVDSDRTRLCDTRSAHPVRHPSDPDCAPVIHLRGDPNSLKCFRYRLHHGKRKLYSRSSSTWRWSCESENQAAFVTLWYTSDTQRTEFLNVVKVPPGIQVILGYMSIF
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PUR3_STAAN
Sequence: MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNKDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
What is the function of this protein?
Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
What are the official names of this protein?
Phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase, GAR transformylase, GART.
What is the protein family that this protein belongs to?
Belongs to the GART family.
Protein: MUTL_CARHZ
Sequence: MPKIKRLPDEVIKKIAAGEVVERPYSVVKELVENSLDAKAQNINVYIEEGGLGKIVVEDDGIGIPPEELPDALLRHTTSKIASFDDLYYLESFGFRGEALYSIAAVSKISIKSRVRGENNGYELIAHAGEVINLTEVGMAYGTVVTVSDLFFNTPARKKFLKSGQTEAGLIRQFIEKMAILYPGVKFSLFIDGKKIYSSAGIQEQLGLLARFWGLEKGNLLMLEEKLGEGFFIKGGIALPPAGKPHRKLQVFAVNKRLVKSGILTKAIDDAYESLLPTGLKPLVFLEVVVPGTWVDVNVHPQKLEVKFMDEQKIYLDVRTIIRNKLVNAKSSSLKSFSPARETNTKSEDNDYWQVTYFAEEFSGNSDKLLEKEDIFSTSDNLTFSLNKDFAKELNFQVIGQFSLKYIIVEKNDKLLIIDQHAAHERILYEKYQTKLNPFYSQVLTFPVRIKASPELEAFLQENYQNFLEIGLHIEPFGPGEYLVREIPEDFPQNNIANVLEEYLYEIMEQKEQVSFREKALKLFACKNAVKFGEKLTYSEMTNLVKELFKTNYPLSCPHGRPTIYELSLTEINKKFFR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ACDH_PARPJ
Sequence: MYDKQDKQAVAIIGSGNIGTDLMIKVLRDAKHLEMGAMVGIDPASDGLARAKRLGVATTAHGIEGLVTMPNFGAIRIAFDATSAGAHHRHAAVLREHGVTVIDLTPAAIGPFVVPVVNLFAHLDAPNLNMVTCGGQATIPIVHAVSRVAPVRYAEIVASIASRSAGPGTRANIDEFTETTSKAIETVGGAARGKAIIVLNPAEPPLMMRDTVYCLTEEEADTDEIESSIRAMVSAVASYVPGYRLKQAVQFDRYTAANPLALHANERRAGLKVSVFLEVEGAAHYLPSYAGNLDIMTSAALAAAEQIAASRVAA
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: PUR5_NITOC
Sequence: MSKKKLPPSSHSPLSYRDAGVDIDAGNQLIQRIKPAANRTTRPGVLTSLGGFGSLFELPIHRYQHPVLVAGTDGVGTKLKLAIQLNRHDSIGIDLVAMCANDIIVQGAEPLFFLDYYATGRLEVDIAAEIIEGIAHGCELAGVALVGGETAEMPGIYQAGDYDLAGFCVGVVEKERLIDGSQVQAGDHLIGIASSGPHANGYSLIRKILERSRYSLNSPLADQTLGDALLTPTRIYVKPLLQLLEVIEIHALAHITGGGLPENLPRVLPPMLSAEIDTSRWPRLPIFDWLQREGNLSEQELYRTFNCGIGMVVCVDQADTEQALEFLKDRGESAWLIGRIVPQTSDGQRVAFNTGNPL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_RUTMC
Sequence: MNVKELRNQDVSTLNETLIKLLKKHFELRMQHKSAQLDDASKLGKTKRSIAQVKTIIRQKQV
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: HPDS_CLODI
Sequence: MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCKNCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE
What is the function of this protein?
Component of the HPA decarboxylase that decarboxylates phenylacetates with a hydroxyl group in the p-position.  Active toward 4-hydroxyphenylacetate, 3,4-dihydroxyphenylacetate and to a lesser extent p-hydroxymandelate (2-hydroxy-2-(4-hydroxyphenyl)acetate), forming 4-methylphenol, 4-methylcatechol and 4-hydroxybenzylalcohol, respectively.  Is likely involved in the catabolism of aromatic amino acids such as tyrosine fermentation.  4-methylphenol (p-cresol) formation provides metabolic toxicity, which may benefit the pathogen C. difficile by suppression of the endogenous gastrointestinal microflora, allowing the development of gastrointestinal infections.  The small subunit is essential for enzymatic activity of HPA decarboxylase, and seems also involved in the regulation of the enzyme oligomeric state and catalytic activity.
What are the official names of this protein?
4-hydroxyphenylacetate decarboxylase small subunit, HPA decarboxylase small subunit, 4-hydroxyphenylacetate decarboxylase gamma subunit, p-hydroxyphenylacetate decarboxylase small subunit.
What is the protein family that this protein belongs to?
Belongs to the HPA decarboxylase small subunit family.
Protein: GCSPA_DESPS
Sequence: MRYLPHTEEEIQEMLEVVGKESLDDLFSSVPAECRYQGDIPIPAALTEWQLKDHFAALMSKNRVNQEHKVLIGAGSYDHYVPEILPSLMSRSEFLTAYTPYQPEVAQGTLQGIFEYQTLTARLLGTDAVNASMYDGASALAESALMSFRIARKKKTVALSAAIHPHYREVVATYLQATDFTIIELPVDAEGRTDLSSLAGIEGLASVAIQSPNFFGVVEDLQGCGEKIHDVDALFISCFSEALAYGLLKSPGECGADIICGEGQSFGLGRSYGGPGVGMMGCRDKLVRNMPGRIVGQTLDTKGKRGFVLTLATREQHIRREKATSNICSNQGICAMTAGMYMATLGGTGIRQLARLNYDKAAYLRSELIKLGAKPLFDAPVFNEFALRFPFDFERVREALKEESVVAGLSLEAYYPDLQGAYLFCATETLKKEDIDRIVSSIKKHALQEV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: PHNC_MYCCT
Sequence: MILFNNVNKVWPNGKQVLKNITLEINKGELVAVIGLSGAGKTTLLKTINKINDISSGEIIIDFDKTKDHYEITKTRGKKLQKLRQKIGLMSQEYNNIANKTVLQNVLNARVSSQKGINKIIGFFKREDKLIALNSLNKLNLLDYAYIRADNLSGGQQQRVALARTLAQQPFLIIADEPVSALDPILANQVMKDFKNINKKDGITVIINIHHVDLAKKYATRVIGLNNGEIVFDDVPSKLDAQAMKKIYGE
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEUC_MYCTA
Sequence: MALQTGEPRTLAEKIWDDHIVVSGGGCAPDLIYIDLHLVHEVTSPQAFDGLRLAGRRVRRPELTLATEDHNVPTVDIDQPIADPVSRTQVETLRRNCAEFGIRLHSMGDIEQGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGRLPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMVAPDETTYAFLRGRPHAPTGAQWDTALVYWQRLRTDVGAVFDTEVYLDAASLSPFVTWGTNPGQGVPLAAAVPDPQLMTDDAERQAAEKALAYMDLRPGTAMRDIAVDAVFVGSCTNGRIEDLRVVAEVLRGRKVADGVRMLIVPGSMRVRAQAEAEGLGEIFTDAGAQWRQAGCSMCLGMNPDQLASGERCAATSNRNFEGRQGAGGRTHLVSPAVAAATAVRGTLSSPADLN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.