PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_ECO27
Sequence: MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNEKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRC22_KOMPG
Sequence: MKFLRLSTLALVGLGFLTQTTLCDPDTDEEFVPTEQKPFNIRVTYEIDEHPQSFESTKLIELVNGEEISVTYNIKNGEDESVSVVGVAGSFNDPVTGLTKRNLTASSVGPLKLLKDMTFEFTQKIGIDLEPENYLFVPSIYVLKDDQLMLLGSKNQLITVSDPQISVFQPQMLFLELVLLASFGGLIYALYATFGASYFQKPATAPKNKKVGSSNVRKTKKNK
What is the function of this protein?
Is probably involved in a pathway contributing to genomic integrity.
What are the official names of this protein?
Increased recombination centers protein 22.
What is the protein family that this protein belongs to?
Belongs to the IRC22 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: BR1D_RANDY
Sequence: FLIGMTHGLICLISRKC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Brevinin-1DYd.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: NUFP1_RAT
Sequence: MAEPTPAGWPSAPELTPAPGTPSEAAPPQDNWVYWAMLPPPPPPLSSPVAGTEPCQKEQPHVEPQPTSGAFPPFDAQILPAAQPPFDAQAPPDGQSQFNDQQAWNFQASTPWYWGLSPNGFPTYNTSFHSPATHSYFPQSYANYNDFNLPQNRKQKKKKRKEPVFHFFCDTCDRGFKNQEKYDIHMSEHKKCPEVDCSFSAHEKIVQFHWRNMHAPGMKKIKLDTPEDIARWREERRKNYPTLANIERKKLLQLEKEKRGEVLTTTQYGKMKGMSRHSQMAKIRSPGKHYKWKSGGARQRAVLGLGNRARDLKPEIPTKVNVDPLGVLIHSDSESDKDEKSQRAIVPKEVTPALCSLMSSYGNVSGSESEPEEAPIKTEAEVLAENRVLPSSPPKSPRHNVRTTARTVLRAKWKAQRSGLRKITLKQKKSPCHPLFEPRTRHPHLLEMLLAPDIRHERNVILQCVRYIIKKDFFGLTAGSVKTEDV
What is the function of this protein?
Binds RNA.
What are the official names of this protein?
FMR1-interacting protein NUFIP1, Nuclear FMRP-interacting protein 1.
What are the subcellular locations of this protein?
Nucleus. Note=Distributed in the nucleus in a dot-like pattern.
Protein: TBB_CHLIN
Sequence: MREIVHIQGGQCGNQIGAKFWEVVSDEHGVDPTGTYHGDSDLQLERINVYFNEATGGRYVPRAILMDLEPGTMDSVRSGPYGQIFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVVRKEAESCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVVPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPTFGDLNHLISAVMSGITCCLRFPGQLNADLRKLAVNLIPFPRLHFFMVGFTPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNVKSSVCDIPPKGLKMSATFIGNSTAIQEMFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASAEEEGEFEGEEEEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: O16D_CONPI
Sequence: YGNFPTCSETGEDCSAMHCCRSMTCRNNICAD
What are the official names of this protein?
Conotoxin pr6d.
What are the subcellular locations of this protein?
Secreted.
Protein: XERC_SHEAM
Sequence: MADQASWLERFTRYLATERQLSPMTVRNYRFELERADTLLGQRSWQQLSRQDLSGLMARLHRQGLSPRSLSLTASALKQFGQFLLKEGLIDTNPAATLSAPKQSKTLPKNLDPDSVNHLLDIPPEDGLALRDKAIMELFYSCGLRLAELAALDVKDLDRESREVRVIGKGSKERILPVGSVALAAIGDWLKVRNQMPCQDDALFVSSRGSRLSHRSIQARMEKWAQIQGLSVGVHPHKLRHSFATHMLESSGDLRAVQELLGHANLATTQIYTSLDFQHLAKVYDGAHPRARKKGD
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFE_SHEB9
Sequence: MTNYREIAWQGLWKNNPGLVQLLGLCPLLAVTATITNALGLGLATMLVLIGSNILVSLVRDYVPKEIRIPVFVMIIAALVTTVQLLINAYAYGLYLSLGIFLPLIVTNCIIIGRAEAFASRNNAFSAAFDGLMMGLGFTLVLTVLGATREILGQGTLFDGADQLLGPWAKSLTIHLWQVDTPFLLAMLPPGAFIVMGLLIALKNVIDKKVKERQPQVAAEPSVTRARITKVG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TNNI2_CAEEL
Sequence: MSEEAGEDAQRKAAEREAKKAEVRKRLEEAGNKKKAKKGFLTPERKKKLRKLLMVKAAEDLKRQQLLKEQERQKALADRTISLPNVDSIDDKGQLEKIYNDLWARLTQLEEEKYDINYVVSQTEAEINSLTIEVNDLRGKFVKPSLKKVSKYDNKFKKSGESKAGTKEDFRANLKIVKKDVMEAIVNVKKKDDKPDWSKKNKDAKAEDSAPAAVAPEAEPVAEEAEAEPEAEEEEGEEEEEE
What is the function of this protein?
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin I 2, CeTNI-2, TnI 2, Uncoordinated protein 27.
What is the protein family that this protein belongs to?
Belongs to the troponin I family.
Protein: CHO2_YEAS8
Sequence: MSSCKTTLSEMVGSVTKDRGTINVKARTRSSNVTFKPPVTHDMVRSLFDPTLKKSLLEKCIALAIISNFFICYWVFQRFGLQFTKYFFLVQYLFWRIAYNLGIGLVLHYQSHYETLTNCAKTHAIFSKIPHNKDANSNFSTNSNSFSEKFWNFIRKFCQYEIRSKMPKEYDLFAYPEEINVWLIFRQFVDLILMQDFVTYIIYVYLSIPYSWVQIFNWRSLLGVILILFNIWVKLDAHRVVKDYAWYWGDFFFLEESELIFDGVFNISPHPMYSIGYLGYYGLSLICNDYKVLLVSVFGHYSQFLFLKYVENPHIERTYGDGIDSDSQMNSRIDDLISKENCDYSRPLINMGLSFNNFNKLRFTDYFTIGTVAALMLGTIMNARFINLNHLFITVFVTKLVSWLFISTILYKQSQSKWFTRLFLENGYTQVYSYEQWQFIYNYYLVLTYTLMIIYTGLQIWSNFSNINNSQLIFGLILVALQTWCDKETRLAISDFGWFYGDFFLSNYISTRKLTSQGIYRYLNHPEAVLGVVGVWGTVLMTNFAVTNIILAVLWTLTNFILVKFIETPHVNKIYGKTKRVSGVGKTLLGLKPLRQVSDIVNRIENIIIKSLIDESKNSNGGAELLPKNYQDNKEWNILIQEAMDSVATRLSPYCELKIENEQIETNFVLPTPVTLNWKMPIELYNGDDWIGLYKVIDTRADREKTRVGSGGHWSATSKDSYMNHGLRHKESVTEIKATEKYVQGKVTFDTSLLYFENGIYEFRYHSGNSHKVLLISTPFEISLPVLNTTTPELFEKDLTEFLTKVNVLKDGKFRPLGNKFFGMDSLKQLIKNSIGVELSSEYMRRVNGDAHVISHRAWDIKQTLDSLA
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LATE_ARATH
Sequence: MEDHYHQVEVEGEEEIKPSKEANKTDENTSSLRIFPCLFCSRKFHSSQALGGHQNAHKKERTAARRAKRAYDFVNNNDFLHTLPVFLSSPSQHHLTILGYPASASVACFPTVHPDHPIFKSSGSHVVLATSHQGRDCKGGYCCQQRVDILDHHYNVVNSDKGKDQCLDLSLHL
What is the function of this protein?
Acts as a transcriptional repressor.  Prevents the photoperiodic and circadian clock-dependent transition to flowering in long days (LD) by repressing the expression of flowering time genes (e. g.  FT, GI and CO) in the leaf vasculature, and by interfering with floral meristem identity genes at the apex (e. g.  SOC1 and LFY).
What are the official names of this protein?
Protein LATE FLOWERING.
What are the subcellular locations of this protein?
Nucleus.
Protein: AAS_SALPA
Sequence: MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLDPTKPMSIKHLMRLVEQGRPVVIFPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRIQLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTKTLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAIAAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTLADKLWIFAHLLAPRLAQVKQQPEDAAIILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKGPNIMNGYLRVEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSADKMHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAIRB_RAT
Sequence: MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKNPLPPSVGVADKKEETQPPVALKKEGIRRVGRRPDQQLQGDGKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIERPIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQKQISYNCSDLEQSNVTEETPEGEEHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
What is the function of this protein?
May play a role in the regulation of mRNA stability.  Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.  Seems to play a role in PML-nuclear bodies formation.
What are the official names of this protein?
Plasminogen activator inhibitor 1 RNA-binding protein, PAI1 RNA-binding protein 1, PAI-RBP1, RDA288, SERPINE1 mRNA-binding protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
Protein: LHX1_MESAU
Sequence: MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEGGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVPSSGPSGTPLGGLDHPLPGHHPSSEAQRFTDILAHPPGDSPSPEPSLPGPLHSMSAEVFGPSPPFSSLSVNGGASYGNHLSHPPEMNEAAVW
What is the function of this protein?
Potential transcription factor.  May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis (By similarity).
What are the official names of this protein?
LIM/homeobox protein Lhx1, LIM homeobox protein 1, Homeobox protein LMX-2, Homeobox protein Lim-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUD_SHIFL
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEAKQPAFMN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: SIKE1_BOVIN
Sequence: MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDIKDMSKYKPHILLSQENTQIRDLQQENRELWVSLEEHQDALELIMSKYRKQMLQLMVAKKAADAEPVLKAHQSHSAEIENQIDRICEMGEVMRKAVQMDDDQFCKIQEKLAQLELENKELRELLSISSESLQVRKESSVDTASQGIK
What is the function of this protein?
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3.  Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter.  May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and RIGI.  Does not inhibit NF-kappa-B activation pathways (By similarity).
What are the official names of this protein?
Suppressor of IKBKE 1, Suppressor of IKK-epsilon.
What is the protein family that this protein belongs to?
Belongs to the SIKE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRAK4_BOVIN
Sequence: MNKPITASTYVRCLSLGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQIGKSPTCELLFDWGTTNCTVGDLVDILVQNEFFAPASLLLPDAVPKNVNTLPSKVTVVAVQQKPKPLCGKDRTSVISDENPEQNYVLPDSSSPENTSLEFSDTRFHSFSFFELKDVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNRTVAVKKLAAMVDISTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWNMRCKIAQGAANGLSYLHENHHIHRDIKSANILLDEDFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYVDRKMNDIDSTSIETMYSVASQCLHEKKNKRPDIKKVQQLLEEMTGS
What is the function of this protein?
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.  Involved in Toll-like receptor (TLR) and IL-1R signaling pathways.  Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2.  Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1.  Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1.  Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex.  In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation.  Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation.  Phosphorylates NCF1 and regulates NADPH oxidase activation after LPS stimulation suggesting a similar mechanism during microbial infections (By similarity).
What are the official names of this protein?
Interleukin-1 receptor-associated kinase 4, IRAK-4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBQL_DICDI
Sequence: MVKINIKSSTDNKFDVDVELGITVADFKKVIATKCSIPADQQRIIYSGRILKDHQTLDEIKIQDGHTVHLVKGAAPPPPPPVEQQVPTPSNTQPQGIPGVPQNINDMMNNPMIQEMFNSRMMDSLLDNPDIFRDMMMGNPEMREVLNNNPEMAQMLSDPRQLRQSLEMMRNPELMREMMRNADRAMINIENHPEGFNLLRRMYTDIQEPLMNAANQQAASQNQTNSNPIQTNTDANPNSQPLPNPWSTNSSSTSSNPTSSSPSSRPTTGSSTNTGASNPWASMFSGGGGGMGGGTNNTGTNNTGSTNNTGASNPWASMFGGGGGGMGGMGGMEGMLGMDPERVQQLLNNPVAQQMMQRLMSDPAMMQQMITMNPQLRQMMDSNPQLREAMNNPEFLNMMTNPENMNAMMQLQQAMGTLRNNGVFPGGMGGMGGMGGMGGMGGMGGMDFSQFGNMFGGMGGMGGMGNNNSSTTRPPVNQEPPEQRFRLQLEQLEELGFVDRAANISALTSTNGNINLAIDRLLR
What is the function of this protein?
Stable protein which acts as an antagonist of nosA by repressing cellular differentiation after the tight-aggregate stage, when cells differentiate into two precursor cell types, prespore and prestalk cells, prior to the formation of fruiting bodies.
What are the official names of this protein?
Ubiquilin, Suppressor of NosA.
Protein: SMAD1_HUMAN
Sequence: MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
What is the function of this protein?
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.  SMAD1 is a receptor-regulated SMAD (R-SMAD).  SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.  May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
What are the official names of this protein?
Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1, SMAD 1, Smad1, hSMAD1, Transforming growth factor-beta-signaling protein 1, BSP-1.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
Protein: TRMD_NITHX
Sequence: MWRTTVLTLFPEMFPGPLGLSLAGRALVAGLWALDVRDIRCSAADRHRSVDDTPAGGGPGMVLRADVLAKAIDAAEFSPDRPRLLMSPRGRPLTQSQIVELSAGPGPLIVCARFEGVDQRVIEARGLAEVSIGDYVLSGGEIPAMALIDACVRLLPGVMGKAESGADESFSHGLLEYPQYTRPQQFEGRPIPDILLSGDHAKVAAWRRAEAEALTKARRPDLWTAWAGQNPPKSNTDG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABFB_ASPKW
Sequence: MFSRRNLLALGLAATVSAGPCDIYEAGDTPCVAAHSTTRALYSSFSGALYQLQRGSDDTTTTISPLTAGGIADASAQDTFCANTTCLITIIYDQSGNGNHLTQAPPGGFDGPDTDGYDNLASAIGAPVTLNGQKAYGVFMSPGTGYRNNEATGTATGDEAEGMYAVLDGTHYNDACCFDYGNAETSSTDTGAGHMEAIYLGNSTTWGYGAGDGPWIMVDMENNLFSGADEGYNSGDPSISYRFVTAAVKGGADKWAIRGANAASGSLSTYYSGARPDYSGYNPMSKEGAIILGIGGDNSNGAQGTFYEGVMTSGYPSDDTENSVQENIVAAKYVVGSLVSGPSFTSGEVVSLRVTTPGYTTRYIAHTDTTVNTQVVDDDSSTTLKEEASWTVVTGLANSQCFSFESVDTPGSYIRHYNFELLLNANDGTKQFHEDATFCPQAALNGEGTSLRSWSYPTRYFRHYENVLYAASNGGVQTFDSKTSFNNDVSFEIETAFAS
What is the function of this protein?
Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose.  Able to hydrolyze 1,5-, 1,3- and 1,2-alpha-linkages not only in L-arabinofuranosyl oligosaccharides, but also in polysaccharides containing terminal non-reducing L-arabinofuranoses in side chains, like L-arabinan, arabinogalactan and arabinoxylan.
What are the official names of this protein?
Alpha-L-arabinofuranosidase B, ABF B, Arabinosidase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 54 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SNX30_MOUSE
Sequence: MAGGPPKALPSTGPQSLRDMPHPLAGSSSEEAVGGDSTPSPDLLMARSFGDKDLILPNGGTPAGTASPASSSSLLNRLQLDDDIDGEARDLFVTVDDPKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRNKLEESQPTHLIPPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNVFLTAKDLNAYKKQGIALLSRVGESVKHVTGGYKLRSRPLEFAAISDYLDTFALKLGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDITEEFLPVLREYVLYSDSMKGVLKKRDQVQAEYEAKLEAVALRKEERPKVPADVEKCQDRMECFNADLKADMERWQSNKRHDFRQLLVGLADKNIQYYEKCLMAWESIIPLLQEKQETK
What is the function of this protein?
Involved in the regulation of endocytosis and in several stages of intracellular trafficking.  Together with SNX4, involved in autophagosome assembly.
What are the official names of this protein?
Sorting nexin-30.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LPXC_SHIFL
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: APT_ARTS2
Sequence: MNQSEPGQTRRSVPVDQLINSLCATVPDYPKPGIIFKDLTPVFANGAALRAVVDALVEPFKGQFDAVAGVEARGFLLAAAAAYATDTGVITVRKAGKLPRKVISEDYALEYGTATLELHTADLPAGSRVLILDDVLATGGTLGAAARLFERCGVHVAGVGVVMELGELRGRSALTGHRVRSLLRL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXO_EMENI
Sequence: MNRETFDIQPIGRFYGSNTAIRRPREIACFSYDDQHKFHLGDSSLRYYYPPQLPADLNRGFDTFQKLDDAADEHIDALLDTIAAMEKETGKRCEADIITWRGMMTKILTAPFDDMNGFEMNATCFQGTMCKQLQRQQRMPPGMASQDLMAYWGYKFETISVLDKTWDEASREEIEGRENLVVNNNAQYCSVVRTGIGRTKLVLGGEVDAIWDSKPERKEDPINWVELKTSAEIRKDWDMVKFERKLLKFWAQSFLLGVPKIVVGFRDQGGILRRLEELETANIPNRVRKSGRGTWDGNICINFAATFLEWLKSVIKEGGTWRLRKAEKSSVIEVYQVEESGTGDILSQAFLSWRSTT
What is the function of this protein?
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity).  The NAD-cap is present at the 5'-end of some RNAs and snoRNAs.  In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity).  Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (By similarity).  Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity).
What are the official names of this protein?
Decapping nuclease RAI1, NAD-capped RNA hydrolase rai1, DeNADding enzyme rai1.
What is the protein family that this protein belongs to?
Belongs to the DXO/Dom3Z family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FB258_ARATH
Sequence: MMRRRNKKTKTVISNPETLEERNKFDEIPHDLVIEILGRLPAKSVARFLTVSKLWATSIRSLDFIKSYPLGSSSKPRTLVASKQVVANPSTGRTIPLPRVKTRRTIATSFFGYDSVSDQYKVLCMTVKAYGDLRDESSQHQVFTLGAKKKSFRMIDTSIIPHRPCSNGVCIDSVVYYVAKTGAGMLHLCIMRFDLSSEILDLFTSLPQEIRPPS
What are the official names of this protein?
Putative F-box protein At5g15670.