PharMolix/UniProtQA huggingface dataset:
Protein: RNAS8_PONPY
Sequence: MAPARAGCCALLLLLLGLWVAEIPVSAKPKDMTSSQWLKTQHMQPSPQACNSAMNNINKYTEQCKDLNTFLHELFSSVATTCQTPNIACKNSRKNCHQSHGPMSLTMCELTSGKYPNCRYKEKHLNAPYIAACDPPQQGDPGYPLVPVHLDKVV
What is the function of this protein?
Has a low ribonuclease activity.
What are the official names of this protein?
Ribonuclease 8, RNase 8.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROB_SALCH
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHIGQMLLTRADMEDRERFLNARDTLRALLDNHIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQQGLFTADPRSNPQAELIKDVYGVDDALRSIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIASGSKPGVIGDVMEGISVGTRFHAQASPLENRKRWIFGAPPAGEITVDEGATAAMLERGSSLLPKGIKSVTGNFSRGEVIRICNLQGRDIAHGVSRYNSDALRRIAGHHSQQIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_VIBVU
Sequence: MIIPALDLIEGQVVRLYQGDYGQVTEYKVDPAEQFNLYHQAGANWLHLVDLTGAKDTTARQLDLIAKLLASTPANIQIGGGVRTEQDVIDLLEAGAQRVVVGSTAVKQPELVKGWMEKYGAEKIVLALDINIDQDGTRKVAISGWQEDSGVTIEALINDYLTVGLQHVLCTDISRDGTLEGSNVELYVDLCKQYPQVQFQSSGGIGSLTDIEALKGSGVAGVIVGRALLDGKFTAEEAFACWQSE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX16_MOUSE
Sequence: MEKLRLLSLRYQEYVTRHPAATAQLETAVRGLSYLLAGRFSDSHELSELVYSASNLLVLLNDGILRKELRKKLPVSLSQQKLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALIQLAKAVLRMLLLIWFKAGIQTSPPIVPLDRETQAQPLDGDHNPGSQEPSYVGKRSHRVVRTLQNSPSLHSRYWGAPQQREIRQKQQQEELSTPPTPLGLQETIAESLYIARPLLHLLSLGLWGQRSWTPWLLSGVVDMTSLSLLSDRKNLTRRERLELRRRTILLLYYLLRSPFYDRFSEAKILFLLQLLTDHIPGVGLVARPLMDYLPSWQKIYFYSWG
What is the function of this protein?
Required for peroxisome membrane biogenesis.  May play a role in early stages of peroxisome assembly.  Can recruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmic reticulum (ER).  May function as receptor for PEX3 (By similarity).
What are the official names of this protein?
Peroxisomal membrane protein PEX16, Peroxin-16, Peroxisomal biogenesis factor 16.
What is the protein family that this protein belongs to?
Belongs to the peroxin-16 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: CLPX_VARPS
Sequence: MAEKKGSSSEKTLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDELPAGEEAREARSDLPTPLEIKTNLDNYVIGQEPAKRMLSVAVYNHYKRLRHKEKAKGDDVELSKSNILLIGPTGSGKTLLAQTLARMLDVPFVMADATTLTEAGYVGEDVENIIQKLLQSCNYEVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQIDTTNILFICGGAFAGLEKVIENRTEASGIGFGASVKSKAQRSITEVFREVEPEDLIKFGLIPELVGRMPVVASLAELSEDALVQILTEPKNAVVKQFTKLLQMEGVDLEIRPAALKAIARKALARKTGARGLRSILEQSLIDTMFELPNATNVDKVVVEESTIDENKPPLLVYREAAKKA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: Y1075_LEIXX
Sequence: MSGHSKWATTKHKKAVIDARRAKSFAKLIKNIEVAAKIGGADLSGNPTLVDAVQKAKKTSVPNDNIDRAIKRGAGLTGESIDYTTIMYEGYGPGGVALLIECLTENKNRAAAEVRTAMTRNGGTMADPGSVAYNFHRKGVIVVPHADGVDEDAVLVAVLEAGAEEVTDLGESFEVLTEATDLVAARTALQAAGIDYDSADAEFVATVTVQTDAEAARKVFRLIDALEDSDDVQNVYTTLDLSAEVQAQLDDE
What are the official names of this protein?
Probable transcriptional regulatory protein Lxx10750.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLOT_PENMO
Sequence: MKALILLLLGACQALQPGLEYQYRYSARVASGIPSINRQFAAAGIQADVTVQMAADYSVVVQFSNIEVGDLNKVLDCDLRAPLPIEYHPLEDYVDLLEKPFRVIMNESHVPSYMEGPEEPIWISNVRKGFVNIFRVPLFWSTELHSTKLNYGAVEETLVGRCQNWYTSMKLPVNLAEEVNVQREHFMEEDIQRDAYSSSYTTKTKSKTSSKTSSKTSSKTSSKTSKTGKTSPGQLANVPHIEDTLWSVRRTTDFDMCENLVSLQIHSSKYTEDIIQRSSVASYLIRGDTHRRIEQVVVEGTITVLTNKEQHEHVDTFTNQTLELKAVREVGEPITVTYDVHPHYDWQYDIERPQGDQFIPLEQVLTGRPVTDQIVNSIMEYIKKTVDDLSHRMEHYPAKPENLAYIIGRLVEAVANLDYPYIQTLYTHFDGKGTMQKYIFVQLVIHAGTEPAVNFAVDNLSDILFYVTFYESIGVSLRTPAPIPKIMHSLINGEEGLHHSLGLMNFATLAHDACLSEDRKHFYFDYSCGPKTTCDPELIITNFIPYLVRELGNQGKDVWQRLIYLQALSNLGTPQTINVLKPIILGVTETNIFMRTNAIWSLSAYNMHKTALSQIYEILMPIIENKGEQFEIRNIAFLTLATWGPGHAWWQQLAVSTWHDPSPQFANFVTTTIYSISDSHTKLAETVSRIKHLCKPAAPASILHSTNFFLHEYLFSEEHGSRVNFAWFASVHGAIPEEVFLRIQREFFYGYTKVLKIDGQQRGLYNLMQLMKQKMTKPQKRPQSSAQEIVSGMWEELKEKIGFTSPESASDATLWLKLDRLIYVALQYHFMEGAPIPYGMYSGKPFYDKDLNTLIAFPTEIGIPFSVLYVAEDATWLNINGNPETSMTSGKMKVNVDFIFETSQVQFVDARAHVPWSKRPAVASGVYADTQLVLPLNVHASFDMYSQEIQLSIEPTNTQKIDVIKFEFIPYTVLENNYPGDVLVIENEYKPILHGEVPLFNDKHQAFPSDVGLWIQVATEGDIHHTPSIYEIITQLFSAHTSTHIWEQSIVFDPTLSTTKTVSFTFNYVSTGGSGSLVDRGDYDDGQISQGSFDEDFGQFSQVAGGSDQDIMEVDSFGTQSQTIERIMRLQQALISSGGHVRTISVEVELQGTPTRNYEASLTWAISSSASTRSSKVQVTLIKHPAVGVLEDPYTICLNAQIVKPHFNPFFTTEDVLTANYHSTVKAELFEGETCEEAPVLLLEASFDVSSNVKERVKEAIEKGCDYSTYAPGIDIITSPLYDHSHITATWTPDFPDNLKNITYYVDDIIKASLSKKIEFDHTSAHHASRVEIDATKCIETGLWTVRTEKPYAVSIINELELPAWANPIFTPAPLATTLLYGLTVGRTPVSCTIDETKVRTADGKVFAYEPSECWNAMTLDTTFDQRGAMLVRNTGQWEVRIIWQKEGLVIDMSPTNFLVNGEPAKGTDNRYTVLHHDDSHTIVFESGTSVKVSDKVEVLLGLDHRGHTTGICGNFDGEPSNDMVGPKGCYYTDGPLFALSWASPGEGCASFMYKNLKRDVVWYQENCPHFTYEPTGVTHADALYDCTEWVYHQRTEGQYHCKALSPMPVCRPECVASHPITTSVEYECRFSGHQQQAQQQQQQQVQGTQWEECFPHFYTLTYPSSCIPQ
What is the function of this protein?
Forms stable clots in the presence of calcium.
What are the official names of this protein?
Hemolymph clottable protein.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in hemolymph.
Protein: CH60_FRATM
Sequence: MAAKQVLFSDEARAKMLDGVNTLANAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELEDKFENMGAQIVKEVASKTADVAGDGTTTATVLAQALLTEGLKAVAAGINPMDLKRGIDKATARLVEELKALSKPCSDPKSIEQVGTISANSDATVGKLIADAMAKVGKEGVITVEEGKGFEDELDVVEGMQFDRGYLSPYFATNQENMTTDLENPYILIVDKKISNIRDLLPILEGVSKSGRALLIIAEDVESEALATLVVNNMRGVVKVCAVKAPGFGDRRKAMLEDIATLTGATFVSEDLSMKLEETNMEHLGTASRVQVTKDNTTIIDGAGEKEAIAKRINVIKANIAEANSDYDREKLQERLAKLSGGVAVIKVGAVTEAEMKEKKDRVDDALHATRAAVEEGIVAGGGVALIRAQKALDGLTGENDDQNHGIALLRKAIEAPLRQIVSNAGGESSVVVNQVKANQGNYGYNAANDTYGDMVEMGILDPTKVTRSALQHAASIAGLMITTEAMIGEIKEAAPAMPMGGGMGGMPGMI
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_BRUA2
Sequence: MAESINSLEELGTVAKTEAAAPVHVQKLDAQGRAYATGKRKDAVARVWVKPGTGKITVNDKEFEKYFARPVLQMILQQPIVASNRAGQFDIVATVAGGGLSGQAGAVRHGISKALTDYEPGLRTVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RL3_PSECP
Sequence: MTATRNVKGLLGTKLGMTQVWDENNKLIPVTVVQADSNVITQLRNAEVDGYVAVQIGYGQIDPRKVTKPLAGHFEKAGVTPRRHVVELRTADAAEYELGQELSVELFAAGQKIDVIGTTKGKGFAGVMKRHGFHGVGASHGAHKNHRKPGSIGGASTPSRVFKGMKMAGRMGAVRHTTLNLTVHAVDAEKSLLLIKGAVPGARGQVVFVRTAVKGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: FMT_KINRD
Sequence: MRLVLAGTPEVAVPALDALLASRHEVVAVLTRPDAAAGRGRKQVASPVALRAREAGLPLLQPEKPGGEEFLAALRELAPDACPVVAYGALVPRAALEVPRFGWLNLHFSLLPAWRGAAPVQRAVMNGDDVTGACVFQLEEGLDTGPVHASFAEPVGPTDTAGDLLSRLAVRGAGVLVEVLDAIEAGTAHAVPQPAEGVSLAPKITVEEARVDWAATATEIDRRVRGCTPEPGAWTTFRGERFKVGPVVPVPDPVPAGRIAVERKRVLVGTAQGSVVLGTVQPAGKKAMSATDWARGTRPQPGEEFS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PITH1_DICDI
Sequence: MAHQCNDSSHSHGVDDGIEYSLNRYLDTGTITCLNEKVKGSVRHIFKSWEDRHDLKHFVESCDDEELIINIPFGAVTQIKSIIIIGGDGGSSPNKMKAYINNSNIDFGNINSFACTQEWNLHEDFEGQIGYSTKPTKFNNINHLTLYFPSNFGSPTTKIYFIALKGVYTSAKREIVNTVYESKPQLQDHKSDIFNGVSHDLS
What are the official names of this protein?
PITH domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PITHD1 family.
Protein: PHF20_MOUSE
Sequence: MTKHPPNRRGISFEVGAQLEARDRLKNWYPAHIEDIDYEEGRVLIHFKRWNHRYDEWFCWDSPYLRPLEKIQLRKEGLHDEDGSSEFQINQQVLACWSDCRFYPARVTAVNKDGTYTVKFYDGVVQTVKHIHVKAFSKDQNIVGNARPKETDHKSLSSSPEKREKFKEQRKVTVNVKKDKVEKALKTEKRPKQPDKEGKLICSEKGKVSEKSLPKNEKEDKENISENEREYSGDAQVEKKPEKDLVKNPQENLKEPKRKRGRPPSITPTAVDSNSQTLQPITLELRRRKISKRSDTPLKRPRLDKNSPQEQSKKRSENSDKDLSRRRSSRLSTNGTREILDPDSIVPDLVHTVDTNPLPDKSPSAKDSAEGQLKSPLEAGQVSSALTCHPIGDGLGAADLELNCKSMGENTMKTEPVSPLAEVQEVSTVEVPNTLKKVDDSVTLNVPAVDLDHKFRCKVLDCLKFFRKAKLLHYHMKYFHGMEKSPEPEEGPGKTHVQTRGSAVPDKTSQESLTRKRVSASSPTAKEKEKTKEKKFKELVRVKPKKKKKKKKKTKPECPCSEDISDTSQEPSPPKTFAVTRCGSSHKPGVHMSPQLHGSDNGNHKGKLKTCEEDNLSESSSESFLWSDEEYGQDVDVTTNPDEELEGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHGVCMGLLEENVPEKYTCYVCQDPPGQRPGFKYWYDKEWLSRGHMHGLAFLDQNYSHQNARKIVATHQLLGDVQRVIQVLHGLQLKMSILQSREHPDLQLWCQPWKQHSGEGRAHPRHIHITDARSEESPSYRTLNGAVEKPSPLPRSVEESYITSEHCYQKPRAYYPAVEQRLVVETRGSALDAAVSPLCENGDDSLSPRLGWPIDQDRSRGDIDPKPSSPKVREYISKNVLPEETPARKLLDRGGEGLVSSQHQWQFNLLTHVESLQDEVTHRMDSIEKELDVLESWLDYTGELEPPEPLARLPQLKHCIKQLLTDLGKVQQIALCCST
What is the function of this protein?
Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage (By similarity).  Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex.  Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes.  As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues.
What are the official names of this protein?
PHD finger protein 20, Hepatocellular carcinoma-associated antigen 58 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROA2_HALH5
Sequence: MTRFDENARSPWTPLHDVKTVELFPLNQRLDGSITLPGSKSLTNRALIISALANSDSMLTGMLKSDDTYWCIQALKRLGVQINVQGETTSIRGIGGQWKSSSLYIGAAGTLARFLLGALAISRSGNWEIEASQSMSKRPIEPLVGVLRELGATIHYLRREGFYPLSIHGNGLAGGTVRLSGQMSSQYISGLLIAAPYADTPVTITVQGSIVQHAYVFLTLHLMKSFGAQVEYDQQLQTIVVHPTPYTCQDIDLEADASTACYFLALAALTKGRIRLNNLTASTTQPDLHMLTVFEKMGCTVTRGSSFIELEGVSQLKGGFQISMNEMSDQALTLAAIAPFADGPITITDVEHIRYHESDRIAVICEALTRLGIQVDEFEDGLTVYPGTPKPTLHPLSTYDDHRVAMSLSLIGTKVKGLRLNDPGCVAKTCPSYFQLLEQLGIQVHYQ
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase 2, 5-enolpyruvylshikimate-3-phosphate synthase 2, EPSP synthase 2, EPSPS 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
Protein: MNS1B_ASPPH
Sequence: MHLPSLSLSLTALAIASPSAAYPHFGSSQPVLHSSSDTTQSRADAIKAAFSHAWDGYLQYAFPHDELHPVSNGYGDSRNGWGASAVDALSTAVIMRNATIVNQILDHVGKIDYSKTNTTVSLFETTIRYLGGMLSGYDLLKGPVSDLVQNSSKIDVLLTQSKNLADVLKFAFDTPSGVPYNNLNITSGGNDGAKTNGLAVTGTLALEWTRLSDLTGDTTYADLSQKAESYLLNPQPKSAEPFPGLVGSNINISNGQFTDAQVSWNGGDDSYYEYLIKMYVYDPKRFGLYKDRWVAAAQSTMQHLASHPSSRPDLTFLASYNNGTLGLSSQHLTCFDGGSFLLGGTVLNRTDFINFGLDLVSGCHDTYNSTLTGIGPESFSWDTSDIPSSQQSLYEKAGFYITSGAYILRPEVIESFYYAWRVTGQETYRDWIWSAFSAVNDYCRTSSGFSGLTDVNAANGGSRYDNQESFLFAEVMKYSYMAFAEDAAWQVQPGSGNQFVFNTEAHPVRVSST
What is the function of this protein?
Involved in the maturation of Asn-linked oligosaccharides.  Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
What are the official names of this protein?
Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B, Class I alpha-mannosidase 1B, Man(9)-alpha-mannosidase 1B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle lumen.
Protein: THII_STRPI
Sequence: MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYAQVKVTADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKEGMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAYLSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPGALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIREVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTFDISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAEKDEVDDLIDNLL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_BRUSI
Sequence: MVFFNLLEAAFLGLIEGLTEFIPVSSTGHLLLIGHFLGFESTGKTFEVLIQLGAILAILSVYSAKLARIATDFPRDARTRRFVLGVLVAFLPAAVIGALAHGFIKGVLFETPMLVCIMLIVGGFILLWVDQLNLRPRYHNVMDYPLPICLAIGFIQCLAMIPGVSRSGSTIVGSLLLGADKRSAAEFSFFLAMPTMAGAFAYDLFKSRNILSFNDGALIVVGFIMAFISGVFVVRHLLDYVSRHGFALFGWWRLIVGSAGMAALIIWG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SERC_PORGI
Sequence: MKKHNFTAGPCILNDLVLKDAASACLNFAGTGLSVLEVSHRDKEFDAVMLEARNLFKELLDVPEGYEVLFLGGGASLQFYQVPLNLLKKKAAFINTGTWATNAIKQAKIMTQVYGGEVEVLASSEDKNFSYIPKDFVIPEDVDYFHFTTNNTIYGTEIRKDFDTKTRLVADMSSDIFSRPIDVSKYDLIYGGAQKNIGPAGATFVLVKTDVLGQVDRPLPDMLNYQIHIKKDSMFNTPPVFPVYVALQTMKWYKELGGVKVLEKMNLDKAALIYDAIDSSKIFRGTVNPEDRSIMNACFVMKDEYKELEKEFATFAASRGMVGIKGHRSVGGFRASLYNALPIESVQSLVSVMKEFEAKH
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO1C_SACS2
Sequence: MIDEKDKPYLEEKVKQASNILPQKIVDDLKNLILNKEIIVTRDEIDKIFDLAIKEYSEGLIAPGEAIGIVAAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTPMMTIYLTDEYKRDRDKALEVARKLEYTKIENVVSSTSIDIASMSIILQLDNEMLKDKGVTVDDVKKAIGRLKLGDFMIEESEDSTLNINFANIDSIAALFKLRDKILNTKIKGIKGIKRAIVQKKGDEYIILTDGSNLSGVLSVKGVDVAKVETNNIREIEEVFGIEAAREIIIREISKVLAEQGLDVDIRHILLIADVMTRTGIVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAARGDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms part of the jaw domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1C, DNA-directed RNA polymerase subunit A''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGR1A_MOUSE
Sequence: MSLALGHGTIAGSTAAPLSEEGEVTSGLQALAVEDTGGPSVSASKAEEEGKGSQEEAGREGSRPEEALEAPSAASDERAEGEAEDWCVPCSDEEVELPANGQSWMPPPSEIQRLYELLATQGTLELQAEILPRRPPTPEAQSEEERSDEEPEAKEEEEEKPHMPTEFDFDDEPMTPKDSLIDRRRTPGSSARSQKREARLDKVLSDMKRHKKLEEQILRTGRDLFSLDSEGPSPTSPPLRSSGNSLFPRQRKY
What is the function of this protein?
Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation.  However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex.  Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1:PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex (PubMed:19124460).  However, its function in DNA damage has been questioned (PubMed:26744420).  During immunoglobulin class switching in activated B-cells is involved in transcription regulation of downstream switch regions at the immunoglobulin heavy-chain (Igh) locus independently of the MLL2/MLL3 complex (PubMed:26744420).  Involved in both estrogen receptor-regulated gene transcription and estrogen-stimulated G1/S cell-cycle transition (By similarity).  Acts as transcriptional cofactor for nuclear hormone receptors.  Inhibits the induction properties of several steroid receptors such as NR3C1, AR and PPARG; the mechanism of inhibition appears to be gene-dependent (By similarity).  May be involved in the regulation of the BMP pathway in extraembryonic development (PubMed:24633704).
What are the official names of this protein?
PAXIP1-associated glutamate-rich protein 1A, PAXIP1-associated protein 1, PTIP-associated protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIPA_NEIMB
Sequence: MSEIKTDDPKRGIKLRGADKTARIPIKVVPLQEKLKKPEWIRAKLPSRKFFEIKDILREQKMHTVCEEASCPNIGECFSKGTATFMIMGDICTRRCPFCDVGHGRPNMLDPDEPRNLAESVKAMNLRYVVITSVDRDDLRDGGAQHFADCIKAIRETSPNTKIEILVPDFRGRLDIALKILAETPPDVMNHNLETHPSLYRKARPGANYQHSLDLLKRYKEMMPHIPTKSGIMVGLGETDEDVREIMRDMRAHNIEMITIGQYLQPSDGHLPVLRYVTPEQFKIFEKEAYELGFSNAAIGAMVRSSYHADEQAAEALRESHGGCGHH
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN581_HUMAN
Sequence: MLVLPSPCPQPLAFSSVETMEGPPRRTCRSPEPGPSSSIGSPQASSPPRPNHYLLIDTQGVPYTVLVDEESQREPGASGAPGQKKCYSCPVCSRVFEYMSYLQRHSITHSEVKPFECDICGKAFKRASHLARHHSIHLAGGGRPHGCPLCPRRFRDAGELAQHSRVHSGERPFQCPHCPRRFMEQNTLQKHTRWKHP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 581.
What are the subcellular locations of this protein?
Nucleus.
Protein: LCFA_HAEIN
Sequence: MEKIWFQNYPKGSEKFLDTSKYESILDMFDKAVREHPDRPAYINMGQVLTFRKLEERSRAFAAYLQNEFKLQRGDRVALMMPNLLQYPIALFGILRAGLIAVNVNPLYTPRELELQLQDSGAVAIVVVSNFASTLEKVVFNTNVKHVILTRMGDQLSFGKRTLVNFVVKYVKKLVPKYKLPHAVTFREVLSIGKYRQYVRPEISREDLAFLQYTGGTTGVAKGAMLTHGNIITNVFQAKWIAEPFIGDHSRTRSAILALPLYHVFALTVNCLLFLELGVTAILITNPRDIEGFVKELKKYRFEAITGVNTLFNALLNNENFKEVDFSALKLSVGGGMAIQQSVATRWHELTGCNIIEGYGMTECSPLIAACPINVVKHNGTIGVPVPNTDIKIIKDDGSDAKIGEAGELWVKGDQVMRGYWQRPEATSEVLKDGWMATGDIVIMDESYSLRIVDRKKDIILVSGFNVYPNEIEDVVMLNYKVSEAVAIGVPHAVSGETIKIFVVKKDDSLTRDELRNHCRQYLTGYKVPKEIEFRDELPKTNVGKILRRVLRDEEIAKRPKH
What is the function of this protein?
Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids.
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase, Long-chain acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Partially membrane-associated.
Protein: CH10_MYXXD
Sequence: MKIRPLQDRLIVKRVAEENKTKGGLFIPDTAKEKPLEGKVIAVGNGKVQEDGKVRPLDIKAGDTILFSKYAGTEIKLDGEEHLILREEDVLGVIEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_XANC5
Sequence: MAAKDIRFGEDARTRMVRGVNVLANAVKATLGPKGRNVVLEKSFGAPTITKDGVSVAKEIELADKFENMGAQMVKEVASKTNDNAGDGTTTATVLAQALIREGAKAVAAGMNPMDLKRGIDQAVKAAVVELKNISKPTTDDKAIAQVGTISANSDESIGNIIAEAMKKVGKEGVITVEEGSGLENELDVVEGMQFDRGYLSPYFINNQQSQSADLDDPFILLHDKKISNVRDLLPVLEGVAKAGKPLLIVAEEVEGEALATLVVNTIRGIVKVVAVKAPGFGDRRKAMLEDMAVLTGGTVISEEVGLALEKATIKDLGRAKKVQVSKENTTIIDGAGDTAAIESRVGQIKTQIEDTSSDYDREKLQERVAKLAGGVAVIKVGASTEIEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRALVAVGELKGANEDQTHGIQIALRAMEAPLREIVANAGEEPSVILNKVKEGSGNYGYNAANGEFGDMVEFGILDPTKVTRSALQNAASIAGLMITTEAMVADAPKKDEPAMPAGGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.