PharMolix/UniProtQA huggingface dataset:
Protein: XYLT_CIOSA
Sequence: MGFRRNFRRVLRKWKVIVYAVSFILLLQAFFTFQSSPNLIEEEHLKRIKELQIRKHQELAQKMLQGERSLVDGKIFLNPHDPGFREQFFKHANDSINILEDHDVGKVAKMEKLPSKLKPHNFEEIQFEAETKIPSIVKYQPKCEITLKDSLSALSRATSDACKQQIADTACKMQDNTLFPESMPRTCPHENKFKFDAPMPATFDPDLRPVRICYMLVVHGRAVRQLRRLLKVIYHRNHYYYIHVDKRSDYLLREIIKETEQYPNIKVAPWRMATIWGGSSLLRTLLRAISDVLKIWKDWDFFINLSALDFPIEKDEKLVQYLTKYRDKNFMKSHGREDDKFIRKQGLNRVFVECDTHMWRLGERTLPKGIIVNGGSDWVALNRRLCDYAVFGNDQLLVQLKHWYEYTLLPAESFFHTLVQNSDMCESFVDNNLRVTNWNRARGCKCQYKHIVDWCGCSPNDFYPADLVRLHTSRPVFFARKFEESINQEVVNHLDFKLHGEYPPGTPGLHSLWENALRVNEKIPPNCDLHVASVLQVEMYKKDEEFSGYVVTFDAGWLKAGESEEVIDGSARVQLQALLSHQPTLRMLDRTSALSKRLESASVGTNWDIKELVLRDWGGLIGPNSDLHLVARWSRSDDDFVVTVVVIDPVNVVADYNDFRTPSKAAGVTETPLSLKKPLRPGRWVVRFYVQRQFTNICAELDFYVTPLEFKDGAEGDSQLREINRGVVDDAQLNAASRNLYSIRTTLNLPHNNLAATELANQAVHVDGAKLRRWVDAVASGAYKAKDACLVAQATETWREAQPRRCYTPRQITPNLCENLNWSSMSPDPKSEMIPVKPDGRIR
What is the function of this protein?
Catalyzes the first step in biosynthesis of glycosaminoglycan.  Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein.  Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.
What are the official names of this protein?
Xylosyltransferase, Peptide O-xylosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family. XylT subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: WNT5B_ORYLA
Sequence: MDNRSVQRRRTGDVRHLLLAAAFLTCNSQLLLVDANSWWSLGLTPIQRPEMYIIGAQPLCSQLSGLSQGQRKLCQLYQDHMTYIGDGAKTGIKECQYQFRQRRWNCSTVDNTSVFGRVMQIGSRETAFTYAISAAGVVNAISRACREGELSTCGCSRTARPRDLPRDWLWGGCGDNVYYGKRFAQEFVDAREREKNYPRGSREHARTLMNLHNNEAGRQAVYNLADVACKCHGVSGSCSLKTCWLQLADFRRVGEFLKEKYDSAAAMRIGRKGRLELLDKRFNPPTPEDLVYIDLSPDYCHRNETTGSLGTQGRFCNKTSEGMDGCELMCCGRGYDQFRVYKHERCHCKFHWCCYVKCKRCSTLVDQFVCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-5b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RHAR_SALDC
Sequence: MANQLILLKKDFFTDEQQAVTVADRYPQDVFAEHTHEFCELVMVWRGNGLHVLNERPYRITRGDLFYIRAEDKHSYTSVNDLVLQNIIYCPERLKLNVNWQAMIPGFQGAQWHPHWRLGSMGMNQARQVINQLEHESNGRDPLANEMAELLFGQLVMTLKRHRYATDDLPATSRETLLDKLITALANSLESSFALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRETGMTPSQWRHLSNQSD
What is the function of this protein?
Activates expression of the rhaSR operon in response to L-rhamnose.
What are the official names of this protein?
HTH-type transcriptional activator RhaR, L-rhamnose operon transcriptional activator RhaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_PROMM
Sequence: MSIGVVVFPGSNCDRDVRWAAQGCLNIPTRFLWHETRDLNGLDAVVLPGGFSYGDYLRCGAIARFAPVLESLVEFVARGGRVLGICNGFQVLTELGLLPGALTRNRSLHFICEDALLTVESNRTPWLMGHQRKDSLTLPIAHGEGRYQCSDETLCQLQDDDAIALRYVNNPNGSVADIAGITNKTGNVLGLMPHPERACDPVIGGVDGRGLLQSLLG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_CYAP4
Sequence: MRLSQMLFVTLREDPAEAEIPSHKLLLRAGYIRRIGSGVYAYLPLMWRVLGKVSQIVRQEMNAAGAQECLLPQIQPAELWQESGRWDTYTKAEGIMFALTDRQDRQLGLGPTHEEVITTIARDLIRTYRQLPQNLYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFDADVESLRVAYGKMHQAYCNILQRCGLKYRAVDADSGAIGGSGSQEFMVLADAGEDEVLYTEDGRYAANVEKAISLPVDAEPSGLTKFEKRETPGTDTIDKLCQFLKCSPTQVVKNVLYQAVYDNGQTVLVLVSIRGDQEVNEVKLQNELVKLAGKFGGKTVLALTVPDAEMQSKWASQSLPLGYIAPDLADSYIAATKDIHPQFVRLVDQTAVDLKNFVTGANESGYHVVGANWAEAKGKKTKAKSGEFALPDGVVDVRKARPGDRALHNPEQTLKTARGIEIGHIFQLGTKYSQAMGATYTNEQGEEVPLVMGCYGIGVSRLAQAAVEQSYDKDGIIWPVAIAPYQAIVVIPNLNETTQVEAATQLYQDLNAAGIETLLDDRNERAGVKFKDADLIGIPYRIVTGRSLAQGKVEVVQRASRSSTEIALDQVIPTLKEWIAAACPS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_FRATH
Sequence: MDLNIKSLAGQEAGSLGVAEGVFAADYNEALIHQVVVAYMAGARQGTKAQKTRSEVSGGGAKPWRQKGTGRARAGTIRSPIFRKGGVTFAAKPKSYKQKVNRKMYSGAVKSILSELLRSGRMTIVEELKLETPKTREFKSVIDSLGVKDVLFVVGVEEFSENLYLSSRNLKNVAVCDSVEINPVSLVCFENVVLTKKAIKEIEEKLV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RECF_PECCP
Sequence: MALTRLLIKDFRNIEAADLALVPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSIQAGRVIRHDQPEFVLHGRIDGTETERSVGLSKNRQGDSKVRIDGSDGHKVAELAQLLPIQLITPEGFTLLNGGPKFRRAFLDWGCFHNEPGFFAAWSNMKRLLRQRNAALRQVSHYGQLRAWDQELVPLAERISEWRAQYSAAIANDIATTCTQFLPEFSLSFSFQRGWDKESEYAELLERQFERDRMLGYTALGPHKADFRIRASGVAVEDMLSRGQLKLLMCALRLAQGEFLTRQNGLRCLYLIDDFASELDSTRRRLLAERLKATHAQVFVSAVSAEQIEDMVGEKGKMFRVEQGKITVQSQD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QNRB4_ECOLX
Sequence: MMTLALVGEKIDRNRFTGEKVENSTFFNCDFSGADLSGTEFIGCQFYDRESQKGCNFSRANLKDAIFKSCDLSMADFRNINALGIEIRHCRAQGSDFRGASFMNMITTRTWFCSAYITNTNLSYANFSKVVLEKCELWENRWMGTQVLGATFSGSDLSGGEFSSFDWRAANVTHCDLTNSELGDLDIRGVDLQGVKLDSYQASLLLERLGIAVMG
What is the function of this protein?
Probably plays a role in resistance to quinolone antibiotics (PubMed:16870791).  Only inhibits ATP-dependent DNA supercoiling by E. coli gyrase at high concentration (30 uM) (PubMed:19060136).  Protects E. coli gyrase supercoiling activity from inhibition by fluoroquinolones (ciprofloxacin) at 0. 1 uM, does not protect M. tuberculosis gyrase activity (PubMed:19060136).
What are the official names of this protein?
Pentapeptide repeat protein QnrB4, Plasmid-mediated quinolone resistance determinant.
What is the protein family that this protein belongs to?
Belongs to the pentapeptide repeat protein family.
Protein: RL32_PSEPF
Sequence: MAVQQNKKSRSARDMRRSHDALEASTLSVEKTTGEVHLRHHVSPEGVYRGRKVIDKGADE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ACCA_BAUCH
Sequence: MSINFIDFEQPIADIEAKIESLTSISSIDKTCDTNFNEEIKRLRDKSIELTRKIFAHLSAWQIAQLARHPCRPYMLDYVQYIFTDFDELAGDRAYADDKAIVGGLARINSRPVMIIGHQKGREIKEKIRRNFGMPAPEGYRKALRLMKMADRFSIPILTFIDTPGAYPGIGAEERGQSEAIATNLREMAYLRVPIVSTIIGEGGSGGALAIGVGDKVNMLKYSTYSVISPEGCASILWKSVDKAPLAAEAMGINAARLKKLKLIDSIIPEPLGGAHRDVAIMAASLKKQLLFDLSELDRMNEQELLDRRYNRIMKYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_BORHD
Sequence: MKTKVGFNRLNRKSSHRKALLKNMVISLFKHEKITSTKAKLSEVKRFAEKLITRAKIDSVHNRREVSKFIHDKFILNKLFTKISPIFKERKGGYVRVIKLGRRYGDAAEMAILELVDKTLEEK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: AMP19_XENBU
Sequence: GPVGLLSSPGSLPPVGGAP
What is the function of this protein?
Has antimicrobial activity against P. wickerhamii and against Gram-positive bacteria B. subtilis and B. megaterium as well as Gram-negative bacteria X. campestris and P. solanacearum.  The synthetic peptide partially inihibts growth of fungi P. capsici, V. dahliae, F. graminearum and F. omysporum.
What are the official names of this protein?
Antimicrobial peptide GP-19.
What are the subcellular locations of this protein?
Secreted.
Protein: SF21_HELAN
Sequence: MADSGHSISVTFPSFHSGGKEHIIRTGCGSVSVTVCGDQEKPPLITYPDLALNHMSCFQGLFVSPESASLLLHNFCIYHINPPGHELGAASIGIDDPVPSIEDLCDQILVVLNYFRLGSVMCMGAMAGAYILTLFSIKYSERVTGLILISPICKAPSWTERFYNKLTSKTLYYYGMCDLVKELLIHRYFSKEVCGNPEIPESDMVLACRKLLDERDSVNVWRYLQAIDSRRDITEELKSLECKTIIFVGDSSPFHDEALQIAEKLGTNCSALVEVHACGSMVTQEQPHAMLIPLENFLKGFGLYRPCRYSNSPRSPLGPSSIDPELLYPEKMGLKLRPIKLRVSPQPRAHKN
What are the official names of this protein?
Pollen-specific protein SF21.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
Protein: FUCO_ECOLI
Sequence: MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQCGVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLGVFQNSGADYLIAIGGGSPQDTCKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKRRKFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHIKAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPHGVANAILLPHVMRYNADFTGEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVGIPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW
What are the official names of this protein?
Lactaldehyde reductase, Propanediol oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: RL5_SYNFM
Sequence: MARLRETYRNEIAPKLSEQFKYKSPMQIPRLSKIILNMGLGDAIQNIKILDSAAEELGMISGQKPVITRARQSIAAFKLRKGMPIGCMVTLRGDRMYEFFDKLVNVALPRVRDFRGVSSRALDGRGNYTLGIKEHIIFPEIDYDKIDKIKGMNITIVTTAKNDDEARTLLALMGMPFKQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SOXA_ALLVI
Sequence: MTKHGFLLATLVLAGATLPIGPVTAATPEEEQAAFQAYFKQRFPNVPEDEFKNGTYAIDPVTRENWEAIEEFPPYENAISQGETLWNTPFADGQGYADCFPDGPAIMNHYPRWDRERGQVMTLPLALNACRTAHGETPLKYKKGPIADLLAYIAFESRGQITRVEIPQDDPRALAAYEQGKRFYFARRGQLNFACAHCHLATSGTKLRTETLSPAYGHTTHWPVYRSEWGEMGTLHRRFAGCNEQVRAKAFEPQGEEYRNLEYFLTYMNNGLELNGPGARK
What is the function of this protein?
C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation.  The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates.  This leads to the intermediary formation of conspicuous sulfur globules inside of the cells.
What are the official names of this protein?
L-cysteine S-thiosulfotransferase subunit SoxA, Cytochrome c550 subunit monoheme, Protein SoxA, SoxAX cytochrome complex subunit A, Sulfur oxidizing protein A, Thiosulfate-oxidizing multienzyme system protein SoxA, TOMES protein SoxA.
What is the protein family that this protein belongs to?
Belongs to the SoxA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL17_SHEPA
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMACSIVRHEVIKTTVAKAKELRRVVEPLITLAKSDSVANRRLAFARTRDAEVVGKLFTELGPRFQERPGGYTRILKCGLRTGDKAPMAYIELVGRPEAAEAVEDTAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: TAL_DICTD
Sequence: MKLFLDTANIQEIKEAWSLGIIDGVTTNPTHISKENKKFRELIEEICSIVDGPISVEAVSLKAEEIVREAEELSKISPNIVVKIPAIKEGIKAAKILSEKGIKTNITLVFSPSQALLAGKVGATYVSPFVGRLNDISEEGINLVADIKKIYSNYGFKTQIIVSAIRNPMHVVKAALIGADVATMRFDILMSLFRHPMTDLGLEQFLKDWEKVPK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESR1_ICTPU
Sequence: MSEEQARAEAPAGARQRRRSELEGYSVSLASLKLSPMYPEEEQRTTGGISSTAHYLDGTFNYTTNPDATNSSVDYYSVAPEPQEENLQPLPNGSSSPPVFVPSSPQLSPFLGHPPAGQHTAQQVPYYLEPSGTSIYRSSVLASAGSRVELCSAPGRQDVYTAVGASGPSGASGPSGAIGLVKEIRYCSVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYVCPATNQCTIDRNRRKSCQACRLRKCYEVGMMKGGFRKERGGRIIKHNRRPSGLKERERGYSKAQSGSDVREALPQDGQSSSGIGGGVADVVCMSPEQVLLLLLRAEPPTLCSRQKHSRPYSELTIMSLLTNMADRELVHMIAWAKKVPGFQDLSLHDQVQLLESSWLEILMIGLIWRSIYTPGKLIFAQDLILDKSEGECVEGMAEIFDMLLATVARFRTLKLKSEEFVCLKAIILLNSGAFSFCSSPVEPLRDGFMVQCMMDNITDALIYYISQSGISVQLQSRRQAQLLLLLSHIRHMSYKGMEHLYSMKCKNKVPLYDLLLEMLDAHRLRPLGKVPRIWADRVSSSPTTTATTPTTNTTTTTTTTTHHPSNGSTCPADLPSNPPGPGQSPSP
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURA_PROM4
Sequence: MANVVVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVEDKVLKLHLIPSGILYPETICLIGSGTVVDPKVMLKEIEMLIENDIDISGLQLASTAHVTMPYHRLIDQAMEKRRGEQKIGTTGRGIGPTYADKAQRNGIRVIDLLDEQKLRERLRIPLAEKNNVLQKIYKELPLDQEKVIEEYLEYGDRLRPHVVDCSRAIHQAARNRKNILFEGAQGTLLDLDHGTYPFVTSSNPVSGGACIGAGVGPTLIDRVIGVAKAYTTRVGEGPFPTELEGSLNDQLCDRGGEYGTTTGRRRRCGWFDGVIGKYAVEVNGLDCIAITKLDVLDELEEIKVCVAYQLDGQKIEYFPSSAEDFSRCKPIFKSLPGWKSSTAECKRLEDLPPSAMAYLRFLAELMEVPIAIVSLGASRDQTIVVEDPIHGPKRALLNI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCW10_YEAST
Sequence: MRFSNFLTVSALLTGALGAPAVRHKHEKRDVVTATVHAQVTVVVSGNSGETIVPVNENAVVATTSSTAVASQATTSTLEPTTSANVVTSQQQTSTLQSSEAASTVGSSTSSSPSSSSSTSSSASSSASSSISASGAKGITYSPYNDDGSCKSTAQVASDLEQLTGFDNIRLYGVDCSQVENVLQAKTSSQKLFLGIYYVDKIQDAVDTIKSAVESYGSWDDITTVSVGNELVNGGSATTTQVGEYVSTAKSALTSAGYTGSVVSVDTFIAVINNPDLCNYSDYMAVNAHAYFDENTAAQDAGPWVLEQIERVYTACGGKKDVVITETGWPSKGDTYGEAVPSKANQEAAISSIKSSCGSSAYLFTAFNDLWKDDGQYGVEKYWGILSSD
What is the function of this protein?
Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation.
What are the official names of this protein?
Probable family 17 glucosidase SCW10, Soluble cell wall protein 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: CLSPN_DROME
Sequence: MSESLAETAAAAENEEQADDSMEKLVFDEEDEQMVSGEDLLGGKSLIMSDDSEAEDGSQEKPLSPKDRRRRMMDSDQEEDAMDQGNGDSIKNSEDVEEEMVSRPKKKVSAIIDSDNDDEQQAEKKTQKEEGKQPVKSKKKRSQVNQEDQEKPVKSNKTKKAVKNKTQANKAEDDQDNPSKEDKPKKVVKNKKQTNKDGKPQTNEEYDHHQQHEKPAKTQKSKKLAKKQKQQEDDKEDNGTEQEKKKPSPKSKAKKSDKSKIDSLMDNEEDAGEDLKMYQEDQEPQKQKTKKSAKKTNKDSKEESGEDQEHQEQKKPLKKIKLDNIDTKEDKEQIVKPKKMAKKNKQKVLSDDESEENQNEKVDQDHDLKKMSSENELEMGSDKEDQEMQEPPKKAKKNKQRMDSESEDEIPKTESEKITSSPKNKLKGLVDSESEPEETAEEVSPVKNKLKGLVDSESEPELDNPEESAGEQEAPMESALSREKPKKAKVVRESAKKALEGMQAIQSEQQRLHREAHINVPYHQPKPRTLKEFLSRRTINAPLATALAGGSPMPSRQPRKSVGLRMTREELEAYAKLMEDRAKEATEFFKSESESDEEDDSENEEPMELKDNPGVMDEMLDNPKTPEQPKNDTEDMTSQAVIEVPVLGEDKTDDTVGDEAMVADSITEEEPIASTSTAAALKLADNFEIQQETNAKSPSKVCLVTEVVELPKLDLSTINITPSSKPATPKISEVIRQLKIEKSLDESPSLKGDPNMVIDLETGDMFAKKPTGVDDLLNRLMKTREAKKHKTTETVNILTTEHGKLEMSKVSIHLHEEEIAKEPKPGAGYMKMQEHLKTLITKKRMEDLRKKQAEEQEKMAEDEEEGMDVDEEYEPEDKPGYAEVTINEDEEIIDKVDSTAEDDGDAEENKNDADEDPEDNPVEDSEDEKNDSESEQECEANPEPETQTRKKNRIIKAFEDDNSDEDDLDLLQTPKPSNVAPITATQLQLSAHKLFDVETRRTASDEENELLDLCSGQFPQTQMLSSDAPSVDTAVISQIPMTQFGGSSQAADELEGLCSGTFATQLPSQAPTQQPEQQEESEVPAAVANRIVSSDEEAQEDALEVDKPRNKKLTKKRPKKKAKLGFSDDEDSDDEVEEFDEESDAEPVEEIPETFVDYDSEENEIVVEMTKKDRKIRAANFVDKEAELSESEWGSADEDEKNMDEYDIELGDEDQFDRDKLRHELGQIHARKMMDQDIREVRKIKELLFEEEEEGANRQRQFRWKNVEAGFSLDDNRTDNGEGNDGSGDEENEHLWRKIRYEREQLLLEKGLKPEVASPLSTSVINTSNNGNSPAIRRLNIISSKKTTVEVKKNSPFLISKTIAGKQQKSAVRGSFLIRDQQTLSKLAGLTKGTSGDVDAAEGTISVKSAKAKNFVFATLTEEEHENRKRKAADILNSSTETGVNFIKKPKLEPRRDKCLIDQLL
What is the function of this protein?
Required for checkpoint signaling in response to DNA replication stress; either resulting from normal embryogenesis or induced by the DNA synthesis inhibitor hydroxyurea (HU).  It is not required for the G2 arrest resulting from DNA double strand breaks induced by ionizing irradiation (IR).  Necessary for the timely phosphorylation of Cdk1 at the mid-blastula transition.  May have a minor role in maintaining genomic stability in mitotic cells.
What are the official names of this protein?
Claspin.
What is the protein family that this protein belongs to?
Belongs to the claspin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPP_SHEWM
Sequence: MQNAPESVLNALVPMVVEQTAKGERSYDIYSRLLKERVIFLVGQVEEHMANLIVAQLLFLESENPDQEISLYINSPGGSVTAGMAIYDTMQFIKPNVSTVCIGQAASMGAFLLAGGAKGKRHCLPNSRVMIHQPLGGFQGQASDFAIHAQEILGIKNKLNNILAEHTGQPLEVIERDTDRDNFMSAAQAAEYGLVDSVFEQRG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDCT_ECOLI
Sequence: MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKTTCLRLIAGFEQLSGGAISIFGKPASNLPPWERDVNTVFQDYALFPHMSILDNVAYGLMVKGVNKKQRHAMAQEALEKVALGFVHQRKPSQLSGGQRQRVAIARALVNEPRVLLLDEPLGALDLKLREQMQLELKKLQQSLGITFIFVTHDQGEALSMSDRVAVFNNGRIEQVDSPRDLYMRPRTPFVAGFVGTSNVFDGLMAEKLCGMTGSFALRPEHIRLNTPGELQANGTIQAVQYQGAATRFELKLNGGEKLLVSQANMTGEELPATLTPGQQVMVSWSRDVMVPLVEER
What is the function of this protein?
Probably part of the ABC transporter complex YdcSTUV.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YdcT.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: PRMA_ECOLC
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB1_CUPMC
Sequence: MTAAKIKVLCVDDSALIRSLMSEIINSQPDMEVVGTAPDPLVARDLIKRVNPDVLTLDVEMPRMDGLDFLERLMRLRPMPVLMVSSLTERGSEITMRALELGAVDFVTKPKLGIREGLLDYTQTIADKIRAASRARVRARAEQSAGAAPVAPMLRAPLLSTEKLIIVGASTGGTEAIKDFLTPLPPDSPAVMIVQHMPAGFTKSFAHRLNGLCRITVKEAEHGERVLPGYAYIAPGDSHLLLARSGANYVAHLSQEAPVNRHRPSVDVLFDSAAIHGGKNVTGVILTGMGKDGARGMLRMREAGAYNLAQDEQSCIVFGMPKEAIAAGGVHEVVPLHQMSQRVMAHLATFGARAQRV
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDPA_SALA4
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTTTVVEMVAELHRVYSAKNKAYGLFNEESELAQALRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGIVLFCHYRYLAVEYLLVTVLNNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPQSTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELSGVSEVSFSEFTAEKGYELEESFPADRSTLRQLTKYAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGK
What are the official names of this protein?
Nucleoid-associated protein SeAg_B2375.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PAX9_SAIBB
Sequence: MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLAQQGHYDSYKQHQPAPQPALPYNHIYSYPSPITAAAAKVPTPPGVPAIPGSVAMPRTWPSSHSVTDILGIRSITDQVSDSSPYHSPKVEEWSSLGRSNFPAAAPHAVNGLEKGALEQETKYGQAPNGLPAVGSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVAGHGWQHAGSTPLSPHNCDIPASLAFKGMQAAREGSHSVTASAL
What is the function of this protein?
Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
What are the official names of this protein?
Paired box protein Pax-9.
What are the subcellular locations of this protein?
Nucleus.