PharMolix/UniProtQA huggingface dataset:
Protein: TREF1_HUMAN
Sequence: MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
What is the function of this protein?
Binds DNA and activates transcription of CYP11A1.  Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.
What are the official names of this protein?
Transcriptional-regulating factor 1, Breast cancer anti-estrogen resistance 2, Transcriptional-regulating protein 132, Zinc finger protein rapa, Zinc finger transcription factor TReP-132.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL3_SALG2
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEYTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGGVPGATGCDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL32_PERMH
Sequence: MAAPKRKKSKAKTAMRKAQWMRKLTVPGLSLCPECGQPKTPHRVCPHCGYYKDKEVVEVV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: KDSB_CHLTE
Sequence: MNAVIVIPARLSSSRLKEKMLADLEGEPLIVRTWQQATKSRLASRVVVATDSERIFAVLREAGAEVVMTSPDLTCGTDRIAEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFGEGPLPDCTTLVFPLKPDERQIIDDPHVVKAVLDTRGNALYFSRSPIPYRRETLPDTKYYRHIGLYAFRADVLKAFVALPPSMLERAESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRRLFRERFGA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR6_CRYNB
Sequence: MAPRKTVGILGGGQLGRMLTHPAALLGIPLLILDSGSYTPAKQTLLPPPPHSHPDGPFTSETHIRKLASACDILTVEIEHVNADVLEAVEKEGLCEVQPSPKTIRLIQNKYDQKKYLAERGVAVAPFEELPANPTEEDFKAIAGRLGLPLMLKAKTLAYDGRGNSPLKSASSEDIQASLKFLGDRPLYAEGWAPFVKEVAVMVVRNKEGEVQSYDAVETIHRESILRVCLTPLRGEKGVNQRARELAEKAVGHLEGAGIFGVEMFLMPDGELLLNEIAPRPHNSGHHTIEACLTSQFENHLRAILSLPLGSTALRVPSAAMVNILGASSTMDAIDKMADNALTVPGAAVHLYGKAESRKARKMGHITVTAESDAELNERLRALLFAQPDAHADWIDLIAPPSPAPAHSHAKPLVGIIMGSDSDLPVMHPATKILEKFGVPYELTITSAHRTPERMVKYAKTAADRGLRAIIAGAGGAAHLPGMVASETSLPVIGVPVKASVLDGVDSLYSIVQMPRGIPCATVGINNSTNAALLAVRILGTSVPALNKATEEYSKALEEEVLAKVDILEEEGWDKYIERLKK
What are the official names of this protein?
Phosphoribosylaminoimidazole carboxylase, AIR carboxylase, AIRC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.
Protein: ASSY_ECO24
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENMENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_ALCBS
Sequence: MSLAVVILAAGKGTRMKSALPKVLHAVAGKPMVQHVVDAAASLEPANTVIVYGHGGEQVKASVTGEQVAWAEQAEQLGTGHAVAQAMPYVKEDMVLVLYGDVPLIRPETLKDFVATVDDSTLALMTLTLDDPNGYGRIVRDGQNNVQRIVEQKDASEAELSIQEINTGILACSRRFLEESLPKLSSNNAQGEYYLTDLIAMASQSGLNVQTLQPNEGWEVDGVNDRVQLARLERIYQQAQAETLMRDGVTLLDPSRLDIRGRVQIASDVIIDVNVILEGDVTIEEGVVIGPNCILRDANIGAGTVIEANTLIDGAIVGEHCQLGPYARLRPGTELADKAKIGNFVETKKSYIGEGSKVNHLTYIGDSKIGKGVNVGAGTITCNYDGANKFQTVLKDGAFIGSNSSLVAPVTIGVNATVGAGSTITKDVGDNGLAVARTQQRNVANWQRPKKG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM44_GIBZE
Sequence: MENRKKAPFEPEEYPPGSLPLLHEQCGEASWIPMCRHACTFETRHFDEIMLNLVENPNLNSKWLFRADVIHDESSHSPVPADVKITEDSPRTRDFEGFSRQRTMVRRLIPRNTLRDAPLDQTCAFYHSRPGAGELDSGGQTDLMRSLVLYMPHASSAGKLPFYHPKVKGICQLHEWNQSTEIGTVSVHFLLFDGEEDGEEVDQVKLGRIAYHLLQTIHKHGHGTAAGYIKRVNHDVVVPRERFQDKYSELKNKYARSLVQSWLETTDPAKHVFEDLGIAAFLIELWRDMYRGVDFPGFVDIGCGNGLLVHILKLEGYDGWGFDARERKSWSQYNSSFSGSPSGKSLQRRLLLPSIIPVETPDANTKVIDPKDVHDGTFPKGTFIISNHADELTPWTPILAAISQCPFISIPCCSHNLTGDRWRAPPPRDKSKPKSMFASLVDWVAQIAEDCGWDVETEMLRIPSTRNTGLVGRRNTKGAEEIDMHAVLQKYGGVQGYYSNVAKLLKSTPRGH
What is the function of this protein?
Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
What are the official names of this protein?
tRNA (uracil-O(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TRM44 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF2_SPIOL
Sequence: MKGHQFKSWIFELREILREIKNSHYFLDSWTQFNSVGSFIHIFFYQERFLKLFDPRIWSILLSPNSQGSTSNRYFTIKGVVLFVVVVLIYRITNRNMVERKNLYLIGLFPIPMNSIGPRNDTLEKSFGSSNINRLIVSLLYLPKGKKISESYFLDPKESTWFLPITKKCIMPESNRGSRWWRNWIGKRRDSSCKISNETVAGIEISFKEKDIQYLEFPFVYYMDDPIRKDHDWELFDCLSLFLRNVSRENWIWLDNVRLVNKDRFFSKVRNVSSNIQYDFTRSSFVQVTDSSQLKESSDQSRDRSNSISNADSEYHTLINKREIQQLKERSILRDPSFLQTEGTEIESDRFPKCLSGYSSMPRLFTAREKQMIIHLLPEEIEQLLENPTRSIRSFFSGRWSELHLGSNPTERSTRDPQLLKKQQDVSFAPSRQSENKEMVNIFKIIKYLQNTVSIHPISSDPGCDMVPKDELDMDSSDKISFLNKNSFFDLFHLFHDRNRGGYALHHDFESEEKFQEMADLFTLSITDPDLVYHRGFSFSIDSCGLDQKQFLNEVFNSRDESKKKSLLVLSPIFYEENESFYRRIRKKGVRISRNVLNRFFLINRSDRSFEYGIQRDQIGNDTLNHRTIRKYMINQDFSNLKKSQKKWFDPLIFLSRTERFMNRDPDAYRYKWFNGSKNFQEHLEHFVSEQKSRFQVVFDQLRINQYSIDWSEVIDKKDLSKSLRFFLSKSLRFFLSKLLLFLSNSLPFFFVSFGNIPINRSEIRIYELKGPNDQLYNPLVESIGLQIVHLKKWKAFLLDDHDTFQKSKFLINGGTISPFLFNKIPKWMIDSFHTRNNSGKSFDNTDSYFSMISHDQNNWLNPVKPFHRSSLISSFYKANQLRFLNNPHHFCFYCNKRFPFYMEKARINNSDFTYRQFLNILFIHNKLFSLCVGKKKHAFLERDTISPIESQVSNIFLPNDFPIRSDLLVRRTIYSIADISGTPLTEGQLVHFERTYCQPLSDMNLSDSEKKNLHQYLNFNSNMGFIYTPCSEKYLLSEKRKKRSLCLKKCVEKGQMYRTFQRDSAFSTLSKWNLFQTYMPWFLTSTGYKYLNFLFLDTFSDLLPILSSSQKFLSILHDIMHGSGISWRILQKKLCLPPWNLISEISSKCLHNLLLPEEMIHRNNESPLIWTHLASPNVREFFYSILFLLFVAGYLVRTHLLFVFRASSELQTEFERVKSLMIPSYMIELRKLLDRYPTSEPNSFWLKNLFLVALEQLGDSLEEIRGSASGDNMLLGGGPGPAYGFKSIRSKKKYLNINLIDILDLISIIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKRVNGDWIDDKIESWVASSDSIDDEEREFLVQFSTLTTEKRIDQILLSLTHSDHLSKNDSGYQLIEQPGAIYLRYLVDIHKKYLMNYEFNTSCLAERRVFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGSLIDASDDIDRDLDTELELLTMMNALTMDMMPEIDQFSITLQFELAKAMSPCIIWIPNIHDLDVNESNYLSLGLFVNYLSRDCERGSTRNILVIASTHIPQKVDPALIAPNQLNTCIKIRRLRIPQQRKHFFTLSYTRGFHLEKKMFHTNGFGSITMGSNVRDLVAFINEALSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLLSNCPIDPISTYMKKKSCNEGDSYLYKWYFELGTSMKKLTILLYLLSCSAGSVAQDLWSLPGPDEKNGITSYGLVENDSYLVHGLLEVEGALVGSSRIEKACSQNDRVTLFLRPELRNPLDMMQNGSCSILDHRFLYEKYESELEEGEGALDPQQIEEDLFNHIVWAPRIWNPWGFLFDCIERPNELGFPYWARSFRGKRSIYDKEDELQENDSEFLQSGTMQYQTRDRSSKEQGFFRISQFIWDPADPLFFLFKDQPFVSVFSHREFFADEEISKGLLTSQMNPPISIFQRWFIKNTQEKHFELLINRQRWLRTNSSLSNGSFRSNTLSESYQYLSNLFLSNGTLLDQMTKTLLRKRWLFPDEMKIGFMQEEKDFPFLSRKDMWP
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ARCA_STAAC
Sequence: MTDGPIKVNSEIGALKTVLLKRPGKELENLVPDYLDGLLFDDIPYLEVAQKEHDHFAQVLREEGVEVLYLEKLAAESIENPQVRSEFIDDVLAESKKTILGHEEEIKALFATLSNQELVDKIMSGVRKEEINPKCTHLVEYMDDKYPFYLDPMPNLYFTRDPQASIGHGITINRMFWRARRRESIFIQYIVKHHPRFKDANIPIWLDRDCPFNIEGGDELVLSKDVLAIGVSERTSAQAIEKLARRIFENPQATFKKVVAIEIPTSRTFMHLDTVFTMIDYDKFTMHSAILKAEGNMNIFIIEYDDVNKDIAIKQSSHLKDTLEDVLGIDDIQFIPTGNGDVIDGAREQWNDGSNTLCIRPGVVVTYDRNYVSNDLLRQKGIKVIEISGSELVRGRGGPRCMSQPLFREDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP4_RAT
Sequence: MAEGRGTHERPDVETQKTELGALMGTTLQRGAQWYLIDSRWFKQWKKYVGFDSWDMYNVGEHNLFPGPIDNSGLFSDPESQTLKEHLIDELDYVLVPTEAWNKLLNWYGCVEGQQPIVRKVVEHGLFVKHCKVEVYLLELKLCENSDPTNVLSCHFSKADTIATIEKEMRKLFNIPAERETRLWNKYMSNTYEQLSKLDNTIQDAGLYQGQVLVIEPQNEDGTWPRQTLQSKSSTAPSRNFTTSSKPSASPYSSMSASLIANGDSTNSSGMHNSGVSRGGAGFSASYNCQEPPSPHIQPGLCGLGNLGNTCFMNSALQCLSNTGPLTEYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRDTHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFILDGLHEDLNRVKKKPYLEPKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRIMEVFLVPADPHCRPIQYRVTVPLMGAISDLCEALSKLSGIAAENMVVTDVYNHRFHKIFQMDEGLSHITPRDDIFVYEICTTPMDGSEYITLPVYFREKKSRPSSTSSGAVLYGQPLLVSVPKHRLTLESLYQAVCERISRYIKQPLPEEFLSSPLEPGACNGSRGSYEGDEEEMDHQEEGKEQLSEVEESGEDSQGGDPTETTQKAKGPPRHKRLFTFSLVNSCGTADINSLATDGKLLKLNSRSTLAIDWDSETRSLYFDEQESEACEKHTSMSQPQKKKKAAIALRECIELFTTMETLGEHDPWYCPTCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPVRALNMSEFVCDRAARPYVYDLIAVSNHYGAMGVGHYTAYAKNRLNGKWYYFDDSSVSLASEDQIVTKAAYVLFYQRRDDECPSTSSPVSFPGSDGGAKLSSSQQDLGEEEAYTMDTN
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from target proteins.  Deubiquitinates PDPK1.  Deubiquitinates TRIM21.  Deubiquitinates receptor ADORA2A which increases the amount of functional receptor at the cell surface.  Deubiquitinates HAS2.  May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3.  This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6. U5 snRNP.  May also play a role in the regulation of quality control in the ER.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 4, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm. Exported to the cytoplasm in a CRM1-dependent manner and recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The relative amounts found in the nucleus and cytoplasm vary according to the cell type.
Protein: PHNW_BACAA
Sequence: MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPKNGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAQRDELLKCKGQARSLSLDLYDQWETMENQNGKWRFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPLVNEKYQSPIITSFIYPEGNFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: GPV_MOUSE
Sequence: MLRSALLSAVLPLLRAQPFPCPKTCKCVVRDAAQCSGGSVAHIAELGLPTNLTHILLFRMDQGILRNHSFSGMTVLQRQMLSDSHISAIDPGTFNDLVKLKTLRLTRNKISRLPRAILDKMVLLEQLFLDHNALRDLDQNLFQQLRNLQELGLNQNQLSFLPANLFSSLRELKLLDLSRNNLTHLPKGLLGAQVKLEKLLLYSNQLTSVDSGLLSNLGALTELRLERNHLRSVAPGAFDRLGNLSSLTLSGNLLESLPPALFLHVSSVSRLTLFENPLEELPDVLFGEMAGLRELWLNGTHLSTLPAAAFRNLSGLQTLGLTRNPRLSALPRGVFQGLRELRVLGLHTNALAELRDDALRGLGHLRQVSLRHNRLRALPRTLFRNLSSLESVQLEHNQLETLPGDVFAALPQLTQVLLGHNPWLCDCGLWRFLQWLRHHPDILGRDEPPQCRGPEPRASLSFWELLQGDPWCPDPRSLPLDPPTENALEAPVPSWLPNSWQSQTWAQLVARGESPNNRLYWGLYILLLVAQAIIAAFIVFAMIKIGQLFRTLIREKLLLEAMGKSCN
What is the function of this protein?
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels.  The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis (By similarity).
What are the official names of this protein?
Platelet glycoprotein V, GPV, Glycoprotein 5.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DUT_RICRO
Sequence: MTITQVKIKKLENFSGSLPEYATEHSAGMDLIAANEQPITIKAAAIQLIPTGIAIALPDSFEAQIRPRSGLAVKHGITVANSPGTIDADYRGEIKVILINLGKEDFIIEKGMRIAQMIIAKYERILWEESISLMETMRGSGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: MRAY_DESHY
Sequence: MWERIFLAAALALTITLILGPLMIPVLRVMKFGQTIREEGPKRHLAKAGTPTMGGIIFLVGIVVSALVMAEKPTSLEMVMVISAMLGYGLIGFIDDFIKVVLHRSLGLRAYQKLIGQIALALLLTWGANRYLGRGTDLVIPFTSIHLELGLFYYPFVSFIIVGITNAVNLTDGLDGLAAGTTLFSMLSYVSIATLAASQGGGVAILAYESDLAVFAAAAVGGCFGFLRFNKNPARVFMGDTGSLALGGALVGLAVLTKTELILLIIGGVYVVEAISVILQVFSYQTTGKRIFRMSPLHHHFELGGWNEWRVVMVFWLASLLCGVLGVTAYMAGMF
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CTXN3_HUMAN
Sequence: MDGGQPIPSSLVPLGNESADSSMSLEQKMTFVFVILLFIFLGILIVRCFRILLDPYRSMPTSTWADGLEGLEKGQFDHALA
What are the official names of this protein?
Cortexin-3, Kidney and brain-expressed protein.
What is the protein family that this protein belongs to?
Belongs to the cortexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PP14C_RAT
Sequence: MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV
What is the function of this protein?
Inhibitor of the PP1 regulatory subunit PPP1CA.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 14C, Kinase-enhanced PP1 inhibitor, PKC-potentiated PP1 inhibitory protein.
What is the protein family that this protein belongs to?
Belongs to the PP1 inhibitor family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein.
Protein: Y4478_ARATH
Sequence: MSTNSYYSSASSSGFRVCPPGVPSKCWCGEEIITFTSKTKENPYRRFYRCAIAMKRENEEHLFKWVDEALLDEIKMVNEKCKRVVENISDLRMNVMANMELLNKNAKQMEEELIKKMEGELLTMKENVEELGHVMAKSALKTVGVAVVIVASIVWLWGRV
What are the official names of this protein?
Uncharacterized protein At4g04775.
Protein: ANFG_RHOCA
Sequence: MTDISEKLDPLVDYIMKNCLWQFNSRGWDRLKQNAGILSQTCEILCGEEPVHETAMDRCYWVDAVILSRAYKARFPWLMAMTKPEIKSLFKALHEKIDHLTVHGSLNTELTVPHY
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.
What are the official names of this protein?
Nitrogenase iron-iron protein delta chain, Dinitrogenase 3 subunit delta, Nitrogenase component I.
Protein: RS13_OCEIH
Sequence: MARIAGIDIPRDKRVVISLTYIYGVGKTTAQQILKEAGVSEDTRVRDLTEDELGRIRQAVDQYNTEGDLRREVSLNIKRLIEIGSYRGIRHRRGLPVRGQKTKNNSRTRKGPRKTMANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RF1_CYAP4
Sequence: MAESYLLDKLKSVELTFHELTRRLADPEVATDPEEFQRVAKARASLEETVDTYDTWKTVQQHLAEARQIAREAASDPELQEMAVQEVNELTEKSAHLEQRLKILLLPRDPNDDKNIMLEIRAGTGGDEASIWAGDLVRLYSRYAESQRWRVKLVSESLGEMGGFKEAILEIQGEQVYSKLKYEAGVHRVQRVPATEASGRVHTSTATVAIMPEVDEVEVKIDPKDIELTTARSGGAGGQNVNKVETAVDLFHKPTGIRIFCTEERSQLQNKERAMQILRAKLYEMKLQEQQSEITSRRRSQVGTGSRSEKIRTYNYKDNRATDHRLGQNFPLNQVLEGDIEGIIQACITQDQQEQLAELAAATA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 36012_ASFP4
Sequence: MLPSLQSLTKKVLAGQCVPTNQHYLLKCYDLWWHDGPITFDHNLKLIKSAGIKEGLDLNTALVKAVRENNYNLIKLFAEWGANINYGLVSVNTEHTWDLCRELGAKETLNEEEILQIFIDLKFHKTSSNIILCHEVFSNNPILQKVNNIKMRIEIFWELRELIEKTDLLNNEFSLSTLLLKYWYAIAIRYNLKEAIQYFYQKYTHLNTWRLTCALCFNNVFDLHEAYEKDKIHMDIEEMMRIACIKDHNLSTMYYCYVLGGNINQAMLTSIQYYNIENMFFCMDLGADAFEEGTIALGEGYKLIKNILSLKIYSPATTPLPKSTDPEIIDHALKNYVSKNMMIFLTYDLR
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-12L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: NRDR_METEP
Sequence: MRCPFCGGPDTQVKDSRPSEDSSAIRRRRVCPDCGGRFTTFERVQLRELVVLKRSGKRVPFDRDKLQRSIDVALRKRTVDPERVERLVSGITRRLESGGEGEVTSEAIGEAVMEGLKGLDDVAYVRFASVYKNFREAQDFQDLLGTLGERLEGEGDLPEDGEAAPAPPDEVVAAPRRGRPARKRA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: HIS4_STAA2
Sequence: MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQYAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRQLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFNB_METM7
Sequence: MILLVSPKDVAEAHEAIEGGADIIDVKNPPEGSLGANFPWVIKETREATPEGMLVSAAIGDVPYKPGTVTLAALGAAISGADYIKVGLYGTRSYQEALDVMKNVTKAVKDSGENKIVVAAGYADAYRVGGVDPLIIPRVARDAGCDVAMLDTAVKDGKTLFDHMSIELLKEFVEETHKYGMKCALAGSIKIEEIPMLKEINCDIVGVRGAACTKGDRNEGRIQKDLVKEIVKVCRQ
What is the function of this protein?
Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
What are the official names of this protein?
(5-formylfuran-3-yl)methyl phosphate synthase, 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase, 4-HFC-P synthase.
What is the protein family that this protein belongs to?
Belongs to the MfnB family.
Protein: RLMN_NITMU
Sequence: MSINLLDFDAKGLTGFCAEIGEKPFRARQLLRWIHRTGEADFDAMSDLAKGLREKLAAAAVIEPPKVISDHTASDGTRKWLLSVGAGNGIETVYIPETSRGTLCISSQVGCALACAFCSTGRQGFNRNLTVAEIIGQLWWANKALTETFTSEAGRERPITNIVMMGMGEPLTNFENVVTSLDLMLDDNAYGLSRRRVTVSTSGIIPAMDRLRERCPVALAVSLHAPNDALRDQLVPINRKYPIRELLGACERYLQSAPRDFITFEYVMLDGVNDSVAQARELVQLVRDIPCKLNLIPFNPFPDSGFRRSSANAVSRFRDVLMEAGLVTTVRKTRGDDIAAACGQLAGKVLDKTRRVPRNIAEAAG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUX8_ARATH
Sequence: MATPNQEAIDTFISITGASDAVALQKLEEHRGDLNQAVNAYFSEGDRNVVREAPVNDDDEMDIDDVIPAPQSPLSMFNAARTIGRPPFSLLDSDFARRVFDSDPLMPRPPFVSHPREVRQIPIEVKDSSGPSGRSSDAPTIEDVTETAHVQGPVTTQGTVIIDEESDDDIPFAPMGRSRQDRPAGSVANNNNQDYNDIEEEMIRAAIEASKKEAEGSSNPLLEERPLHMEDDDDIAIAVTMSLKSAEEEVLRSQGYKASTSEIGASAVTAAQGPQDTQALNGRLAAPSSPFDDDSDDVDEQPLVRHRPRRAASGSLAPPNADRSRSGSPEEEHASINPAERGSGFPSEWGGISSEEHDEAVMLEAAMFGGIPETGYNHLPFLPPQPRAQPRPPSPSLTAQRLIREQQDDEYVASLQADRDKEMKSIRDAEARQLEEETARKAFLEEEKKKEEEAQRKLEEEQELERQLDAKEASLPKEPQADEENAITLLIRMPDGTRRGRRFLKSDKLQTLFNFIDIARVVKPNTYRLVRPYPRHAFGDGESESTLNDLGLTSKQEALFLELI
What are the official names of this protein?
Plant UBX domain-containing protein 8, PUX8, Ara4-interacting protein, Suppressor of ARA4-induced defect of ypt1, SAY1.