PharMolix/UniProtQA huggingface dataset:
Protein: SOX1_CHICK
Sequence: MYSMMMETDLHSPGGAPAPGGGLSGQSGAGGGGGGGGGGGGKAGQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLGAGPAAGGPPAVGVGMGVGVIPGGVGQRLESPGGAAGGGYAHMNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGGGGHPHHPHPHHPHHPHNPQPMHRYDMGALQYSPISNSQGYVSASPSGYGALPYGSQPHQNSAAAAAAAAAAAAASSGALGALGSLVKSEPSVSPPVTSHSRAPCPGDLREMISMYLPGGEGGDPAAAAAQSRLHSLPQHYQSASTGVNGTVPLTHI
What is the function of this protein?
Transcriptional activator.  May function as a switch in neuronal development.  Keeps neural cells undifferentiated by counteracting the activity of proneural protein and suppresses neuronal differentiation.
What are the official names of this protein?
Transcription factor SOX-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: XLNR_ASPNG
Sequence: MSTPSIPQFTSSFSPFSSGSHSTGMAPSQTVGLDTLAEGSQYVLEQLQLSRDAAGTGAGDGATSTSLRNSMSHTKDQPPFDNEKNQSTGSGFRDALQRDPLVEARSAVRKTSSSAPVRRRISRACDQCNQLRTKCDGQHPCAHCIEFGLTCEYARERKKRGKASKKDLAAAAAAATQGSNGHSGQANASLMGERTSEDSRPGQDVNGTYDSAFESHHLSSQPSHMQHASTAGISGLHESQTAPSHSQSSLGTTIDAMHLNHFNTMNDSGRPAMSISDLRSLPPSVLPPQGLSSGYNASAFALVNPQEPGSPANQFRLGSSAENPTAPFLGLSPPGQSPGWLPLPSPSPANFPSFSLHPFSSTLRYPVLQPVLPHIASIIPQSLACDLLDVYFTSSSSSHLSPLSPYVVGYIFRKQSFLHPTKPRICSPGLLASMLWVAAQTSEAAFLTSPPSARGRVCQKLLELTIGLLRPLVHGPATGEASPNYAANMVINGVALGGFGVSMDQLGAQSSATGAVDDVATYVHLATVVSASEYKAASMRWWTAAWSLARELKLGRELPPNVSHARQDGERDGDGEADKRHPPTLITSLGHGSGSSGINVTEEEREERRRLWWLLYATDRHLALCYNRPLTLLDKECGGLLQPMNDDLWQVGDFAAAAYRQVGPPVECTGHSMYGYFLPLMTILGGIVDLHHAENHPRFGLAFRNSPEWERQVLDVTRQLDTYGRSLKEFEARYTSNLTLGATDNEPVVEGAHLDHTSPSGRSSSTVGSRVSESIVHTRMVVAYGTHIMHVLHILLAGKWDPVNLLEDHDLWISSESFVSAMSHAVGAAEAAAEILEYDPDLSFMPFFFGIYLLQGSFLLLLAADKLQGDASPSVVRACETIVRAHEACVVTLNTEYQRTFRKVMRSALAQVRGRIPEDFGEQQQRRREVLALYRWSGDGSGLAL
What is the function of this protein?
Transcriptional activator of the xylanolytic system.  Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose.  Binds to the DNA sequence 5'-GGNTAAA-3'.
What are the official names of this protein?
Xylanolytic transcriptional activator xlnR, Xylanase regulator.
What is the protein family that this protein belongs to?
Belongs to the xlnR/xlr1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: O167_CONAE
Sequence: MKLTCVLIVAVLFLTACQLIAADDSRDLQKFPRRKMRDGMLNTKNTKRQCLPPLHWCNMVDDECCHFCVLLACV
What are the official names of this protein?
Conotoxin ArMKLT2-041.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL30_STRA5
Sequence: MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIRGMVNAISHLVTVEEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: DTD_METCA
Sequence: MIALIQRVTQASVRVDGATVGAIGRGTLALVAIERGDGATQVSRMAERLLGYRMFPDSENRMNLSLAETGGGLLLVSQFTLAADTAKGMRPSFTPAADPETGRRLFDALVDATQRRHSPVATGRFGADMQVFLVNDGPVTFLLRCPPDRPPGG
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPF_STRPI
Sequence: MSLKDRFDRFIDYFTEDEDSTVPYEKGNEPVFTPVNSSQEPDLPMNQPSQSAGAKDSNITRLHARQQELANQSQRSTDKVIIDVRYPRKYEDATEIVDLLAGNESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRLPDEEQNGEFGFDMKRNRVR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: YCGR2_PARPJ
Sequence: MIADLSLDADVAEQTQQTLGADSNFAQRHPLQIAVCLRQLVAGQDFVTVEFGGRQIVTQILDVDSRNARFVFDAGSVADDNDALPSARQLTFRSLPGGIRTEFTTFDATPTQFDGLPAFEAPLPTVLHYVQRREFFRVQTPVLDPYIASGRYADGGSFRLELLDLSLGGIALKTADERFGSLERGTVLRDVALQLGGFGMLRLDLEIVAPRQVSTAKGDRRFVIGCKFVATPGPAERTLQRVVTQLETRRQALTPRR
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  Binds 1 c-di-GMP dimer per subunit.  Increasing levels of c-di-GMP lead to decreased motility.
What are the official names of this protein?
Flagellar brake protein YcgR 2, Cyclic di-GMP binding protein YcgR 2.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: VDE_ARATH
Sequence: MAVATHCFTSPCHDRIRFFSSDDGIGRLGITRKRINGTFLLKILPPIQSADLRTTGGRSSRPLSAFRSGFSKGIFDIVPLPSKNELKELTAPLLLKLVGVLACAFLIVPSADAVDALKTCACLLKGCRIELAKCIANPACAANVACLQTCNNRPDETECQIKCGDLFENSVVDEFNECAVSRKKCVPRKSDLGEFPAPDPSVLVQNFNISDFNGKWYITSGLNPTFDAFDCQLHEFHTEGDNKLVGNISWRIKTLDSGFFTRSAVQKFVQDPNQPGVLYNHDNEYLHYQDDWYILSSKIENKPEDYIFVYYRGRNDAWDGYGGAVVYTRSSVLPNSIIPELEKAAKSIGRDFSTFIRTDNTCGPEPALVERIEKTVEEGERIIVKEVEEIEEEVEKEVEKVGRTEMTLFQRLAEGFNELKQDEENFVRELSKEEMEFLDEIKMEASEVEKLFGKALPIRKVR
What is the function of this protein?
Part of the xanthophyll (or violaxanthin) cycle for controlling the concentration of zeaxanthin in chloroplasts.  Catalyzes the two-step mono de-epoxidation reaction.  Stereospecific for all-trans xanthophylls.  Zeaxanthin induces the dissipation of excitation energy in the chlorophyll of the light-harvesting protein complex of photosystem II.
What are the official names of this protein?
Violaxanthin de-epoxidase, chloroplastic, AtVxDE, Protein NON-PHOTOCHEMICAL QUENCHING 1.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: FLPA_METWO
Sequence: MMKHVKGMDGVFIMRDSLVTVNLTPGVRVYGEKLIEWGGSEYRVWDPRRSKMAAAVLNGLRGFQLNPESRVLYLGASAGTTASHISDIVTMGRVYCVEFSPRMMRELIEVCRVRGNMVPLLEDASRPLDYMRMVENADLVYCDVAQPDQTGLFIRNMDCFLKDDGYGLIMVKARSIDVTRSPRKIFREEAGKLRDSGFRIIDQVGLKPYEKDHMAILVQRSV
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: GLMU_HALH5
Sequence: MSNRFAVILAAGQGTRMKSKLYKVLHSVCGKPMVQHVVDQVSALGFDEIVTIIGHGADAVKSQLGERVSYALQEEQLGTGHAVLQAESALGGRRGVTIVLCGDTPLLTAETIDHVMSYHEEEQAKATVLTAELADPTGYGRIVRNDKGLVERIVEHKDATSEEKQITEVNTGTYCFDNEALFQALKEVGNNNAQGEYYLPDVIQILQTKGEKVAAYKTAHVEETLGVNDRVALAQAEQVMKRRINEAWMRKGVTFIDPEQTYVSPDATIGQDTVIYPGTMVLGQTTIGEGCVLGPHTELKDSKIGNKTAVKQSVVHNSEVGERVSIGPFSHIRPASMIHDDVRIGNFVEVKKSTIGKESKASHLSYIGDAEVGERVNFSCGSITVNYDGKNKFLTKIEDDAFIGCNSNLIAPVTIGKGALIAAGSTITEDVPSDALSIARARQTNKEHYVTKKNN
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
Protein: HSP72_PARBA
Sequence: MAPAIGIDLGTTYSCVGIFRDDRIEIIANDQGNRTTPSFVAFTDTERLIGDAAKNQVAMNPSNTVFDAKRLIGRKFADPEVQSDMKHFPFKVIDKAGKPVISVEFKGEEKQFTPEEISSMVLTKMRETAESYLGGTVNNAVVTVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDKKAEGERNVLIFDLGGGTFDVSLLTIEEGIFEVKSTAGDTHLGGEDFDNRLVNHFVNEFKRKHKKDLSSNARALRRLRTACERAKRTLSSAAQTSIEIDSLYEGIDFYTSITRARFEELCQDLFRSTMDPVERVLRDAKIDKSSVHEIVLVGGSTRIPRIQKLVSDFFNGKEPNKSINPDEAVAYGAAVQAAILSGDTTSKSTNEILLLDVAPLSVGIETAGGVMTPLIKRNTTIPTKKSETFSTFADNQPGVLIQVFEGERARTKDNNLLGKFELTGIPPAPRGVPQIEVTFDVDANGIMNVSALEKGTGKTNKIVITNDKGRLSKEEIERMLAEAEKYKAEDEAEASRISAKNGLESYAYSLRNTISDSKVDEKLDASDKEKLKTEIDKTVSWLDENQTATKEEFEAQQKELESVANPIMMKFYGAGGEGGAPGAGFPGAGGPGGFPGAGAGGAHSGGDDGPTVEEVD
What are the official names of this protein?
Heat shock 70 kDa protein 2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PCSK9_COLGU
Sequence: MGTVSSRRSWWPLPLPLLLLLLLGLAGARAQEDEDGDYEELVLALRSEEDGLADAPEHGATATFHRCAKDPWRLPGTYVVVLKEETHRSQSERTARRLQAQAARRGYLTKILHVFHHLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQSIPWNLERITPARYRADEYQPPKGGSLVEVYLLDTSIQSDHREIEGRVMVTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPLVVLLPLAGGYSRVFNAACQRLARAGVVLVTAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRLIHFSAKDVINEAWFPEDQRVLTPNLVAALPPSTHRAGWQLFCRTVWSAHSGPTRMATAVVRCAPDEELLSCSSFSRSGKRRGERIEAQGGKRVCRAHNAFGGEGVYAIARCCLLPQVNCSVHTAPPAGASMGTRVHCHQQGHVLTGCSSHWEVEDLGTHKPPVLRPRGQPNQCVGHREASIHASCCHAPGLECKVKEHGIPAPQEQVIVACEDGWTLTGCNALPGTSHVLGAYAVDNTCVVRSRDVSTTGSTSEEAMAAVAICCRSRHLVQASQELQ
What is the function of this protein?
Crucial player in the regulation of plasma cholesterol homeostasis.  Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments.  Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway.  May prevent the recycling of LDLR from endosomes to the cell surface or direct it to lysosomes for degradation.  Can induce ubiquitination of LDLR leading to its subsequent degradation.  Inhibits intracellular degradation of APOB via the autophagosome/lysosome pathway in a LDLR-independent manner.  Involved in the disposal of non-acetylated intermediates of BACE1 in the early secretory pathway.  Inhibits epithelial Na(+) channel (ENaC)-mediated Na(+) absorption by reducing ENaC surface expression primarily by increasing its proteasomal degradation.  Regulates neuronal apoptosis via modulation of LRP8/APOER2 levels and related anti-apoptotic signaling pathways (By similarity).
What are the official names of this protein?
Proprotein convertase subtilisin/kexin type 9, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Endosome. Lysosome. Cell surface. Endoplasmic reticulum. Golgi apparatus. Note=Autocatalytic cleavage is required to transport it from the endoplasmic reticulum to the Golgi apparatus and for the secretion of the mature protein. Localizes to the endoplasmic reticulum in the absence of LDLR and colocalizes to the cell surface and to the endosomes/lysosomes in the presence of LDLR. The sorting to the cell surface and endosomes is required in order to fully promote LDLR degradation (By similarity).
Protein: YEW7_YEAST
Sequence: MCESSNKTENDIVRLSQAMDVLAKLIISKQKDGSQLQVEYEHKLKELEKFINLLLGLHESTVGSMMNTSVLDMVLRNGIEIMEKDDQKYALIPIKAKEEADKTTSTIQGVTSKKSSKKKKNKIKCSFCHEAGHTRAHCGARLTVIPKK
What are the official names of this protein?
Uncharacterized protein YEL137C.
Protein: TRPC_METS5
Sequence: MPRYLEGWIKDVVENAKRRPYVSRSREKPVLQIIPRIRAVKGAGLNPVIAEYKRKSPSGFSEDRDPISYAKSMEQGGAVAISVITENTVFGGSYEYLERIARNVKIPLLMKDFVVSENQVDTAYDLGADFVLLIVRILTERELSGLLEYVRSYGMEALVEVHDREDLDIALRSGASLIGVNSRDLFSLTIQKEMAMKLLEQIPSTVTKVAESGIESAEEIRLLREKGADAFLIGSSLMRNPDKIKEFVQG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: C94C1_ARATH
Sequence: MLLIISFTIVSFFFIIIFSLFHLLFLQKLRYCNCEICHAYLTSSWKKDFINLSDWYTHLLRRSPTSTIKVHVLNSVITANPSNVEHILKTNFHNYPKGKQFSVILGDLLGRGIFNSDGDTWRFQRKLASLELGSVSVRVFAHEIVKTEIETRLLPILTSFSDNPGSVLDLQDVFRRFSFDTISKLSFGFDPDCLRLPFPISEFAVAFDTASLLSAKRALAPFPLLWKTKRLLRIGSEKKLQESINVINRLAGDLIKQRRLTGLMGKNDLISRFMAVVAEDDDEYLRDIVVSFLLAGRDTVAAGLTGFFWLLTRHPEVENRIREELDRVMGTGFDSVTARCDEMREMDYLHASLYESMRLFPPVQFDSKFALNDDVLSDGTFVNSGTRVTYHAYAMGRMDRIWGPDYEEFKPERWLDNEGKFRPENPVKYPVFQAGARVCIGKEMAIMEMKSIAVAIIRRFETRVASPETTETLRFAPGLTATVNGGLPVMIQERS
What is the function of this protein?
Involved in the oxidation of the plant hormone jasmonoyl-L-isoleucine (JA-Ile), a bioactive phytohormone of the jasmonate-mediated signaling pathway.  Converts 12-hydroxy-JA-Ile (12OH-JA-Ile) to the carboxy-derivative 12COOH-JA-Ile (PubMed:17868380, PubMed:22215670, PubMed:26164240).  Exerts negative feedback control on JA-Ile levels and plays a role in attenuation of jasmonate responses (PubMed:22215670).  Functions also as in-chain fatty acids hydroxylase in vitro (PubMed:17868380).  Catalyzes the hydroxylation of 12-hydroxy-jasmonoyl-L-phenylalanine (12OH-JA-Phe) in vitro.  Converts 12OH-JA-Phe to the carboxy-derivative 12COOH-JA-Phe (PubMed:26164240).
What are the official names of this protein?
Cytochrome P450 94C1, 12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RK20_ORYSJ
Sequence: MTRVPRGYIARRRRAKMRSFASNFRGAHLRLNRMITQQVRRAFVSSHRDRVRQKRDFRRLWISRINAATRIHKVFDNYSKLIHNLYKKELILNRKILAQVAVLNSNNLYTISNKIKIIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DISA_MYCS2
Sequence: MAVKSGARSGRNVVHLARPTLRETLGRLAPGTPLRDGLERILRGRTGALIVLGYDDSVEAICDGGFVLDVRYAPTRLRELSKMDGAVVLSSDGSRILRANVQLVPDPSIPTDESGTRHRSAERTAIQTGYPVISVSHSMSIVTVYVAGERHVVPDSATILSRANQTIATLERYKGRLDEVSRQLSTAEIEDFVTLRDVMTVVQRLEMVRRISLEIDADVVELGTDGRQLKLQLDELVGDNETARELIVRDYHANPDPPTAAQVAATLEELDSLSDSELLDFTVLARVFGYPSTAEAQDSAMSSRGYRAMAAIPRLQFAHVDLLVRSFGSLQNLLAASADDLQSVDGIGSMWARHIREGLSLLAESTIADRLA
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic-di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: Y1980_STAAR
Sequence: MNGQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQEIILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
What are the official names of this protein?
UPF0421 protein SAR1980.
What is the protein family that this protein belongs to?
Belongs to the UPF0421 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GSH1_ALIFM
Sequence: MTEFINRLQKVASNPNAFKKTGRGIERETLRFTPGASLSTKPHPEGVGSALTHKYITTDFAESLLEFITPVSNDVDTVLKQLEDVHHYTVSHMGDEKLWPLSMPCFVTHDDDITLAQYGESNVGKLKTTYREGLKRRYGSVMQVISGVHFNFSFSTEFWDELFGEQSEDQRKESVSDAYFALIRNYYRFGWLIPYFFGASPALCSSFIQGRETSMDFESLGKTYYLPYATSLRLSDLGYTNDAQSNLKISLNSVNEYVDGLNKAIRTPSEEFAKIGLKEGDKHIQLNSNVLQIENELYAPIRPKRVAKSGERPSEALERDGVEYIEVRSLDVNPYSPIGVNEDQVRFLDMFLTWTVLSDSAPMNDSEMACWKDNWNKIIEKGRKPGLELKIGCQGERLTQKAWAERVFEDLLIIAKEMDRVNGDDAYQQTHKRLSAMIDDPELTISGRLLAETKAAGGIGVIGCKLAVEHRETHLAHQYRFYTKQELDTEVERSVQAQKEIEANDKLSFSEYLEEYFSYLK
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: ETR1_ARATH
Sequence: MEVCNCIEPQWPADELLMKYQYISDFFIAIAYFSIPLELIYFVKKSAVFPYRWVLVQFGAFIVLCGATHLINLWTFTTHSRTVALVMTTAKVLTAVVSCATALMLVHIIPDLLSVKTRELFLKNKAAELDREMGLIRTQEETGRHVRMLTHEIRSTLDRHTILKTTLVELGRTLALEECALWMPTRTGLELQLSYTLRHQHPVEYTVPIQLPVINQVFGTSRAVKISPNSPVARLRPVSGKYMLGEVVAVRVPLLHLSNFQINDWPELSTKRYALMVLMLPSDSARQWHVHELELVEVVADQVAVALSHAAILEESMRARDLLMEQNVALDLARREAETAIRARNDFLAVMNHEMRTPMHAIIALSSLLQETELTPEQRLMVETILKSSNLLATLMNDVLDLSRLEDGSLQLELGTFNLHTLFREVLNLIKPIAVVKKLPITLNLAPDLPEFVVGDEKRLMQIILNIVGNAVKFSKQGSISVTALVTKSDTRAADFFVVPTGSHFYLRVKVKDSGAGINPQDIPKIFTKFAQTQSLATRSSGGSGLGLAISKRFVNLMEGNIWIESDGLGKGCTAIFDVKLGISERSNESKQSGIPKVPAIPRHSNFTGLKVLVMDENGVSRMVTKGLLVHLGCEVTTVSSNEECLRVVSHEHKVVFMDVCMPGVENYQIALRIHEKFTKQRHQRPLLVALSGNTDKSTKEKCMSFGLDGVLLKPVSLDNIRDVLSDLLEPRVLYEGM
What is the function of this protein?
Ethylene receptor related to bacterial two-component regulators.  Acts as a redundant negative regulator of ethylene signaling (PubMed:15466228, PubMed:15703053).  In the presence of ethylene, the auto-kinase activity of ETR1 is inhibited and the non-phosphorylated kinase domain binds tightly to the corresponding domain of EIN2 (PubMed:20591837).
What are the official names of this protein?
Ethylene receptor 1, AtETR1, Protein ETHYLENE RESPONSE 1, Protein ETR1.
What is the protein family that this protein belongs to?
Belongs to the ethylene receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: C16L2_MOUSE
Sequence: MAAPGPRALRAALCGGCCCLLLCAQLVLAGKGARGFGRGALLRLNVWPTTQGGCKHLGHCEHCVDRAHNFSICVWQQCGPEEPGHCVAQAEVVKEGCSIYNHSESCPASHHHSTEEPKPSTTGSPPIPEDHSPGFDGASFIGGIVLVLSLQATAFFVLRFLKAKDSTYQTLI
What are the official names of this protein?
CD164 sialomucin-like 2 protein.
What is the protein family that this protein belongs to?
Belongs to the CD164 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: WOX12_ARATH
Sequence: MNQEGASHSPSSTSTEPVRARWSPKPEQILILESIFNSGTVNPPKDETVRIRKMLEKFGAVGDANVFYWFQNRRSRSRRRHRQLLAATTAAATSIGAEDHQHMTAMSMHQYPCSNNEIDLGFGSCSNLSANYFLNGSSSSQIPSFFLGLSSSSGGCENNNGMENLFKMYGHESDHNHQQQHHSSNAASVLNPSDQNSNSQYEQEGFMTVFINGVPMEVTKGAIDMKTMFGDDSVLLHSSGLPLPTDEFGFLMHSLQHGQTYFLVPRQT
What is the function of this protein?
Transcription factor which may be involved in developmental processes.
What are the official names of this protein?
WUSCHEL-related homeobox 12.
What is the protein family that this protein belongs to?
Belongs to the WUS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACP_KARMG
Sequence: MNEILSKIKSIIIEKLGVDEKKVIPEASFINDLGADSLDSIELIMEFEKEFDIIISDDIAEKLITVDDANQYIKKYLDDKKSF
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
Protein: PFEE_PSEAE
Sequence: MRTSLLVAALGLALAAALPGGAPLAQPDPEATMDRSLLQRQDLPYRFSAVDLDSVDGQRHYRLWLGRPLQAPPAAGYPVVWMLDGNAAVGALDESTLRRLADGDAPLLVAIGYRTPLRIDRAGRTFDYTPASPGQADQRDPLNGLPSGGADAFLDLLRDGMRPAVAAQAPLDTARQTLWGHSYGGLLVLHALFTRPGEFARYAAASPSLWWRDGAILGERAGLEQRLRGKRAELLLWRGSAEPASPRGSLKAEPGQAMARLVDDLRRVAGLTLDFQPLDGLGHGETLGASLRLLLARPAVERQR
What is the function of this protein?
Catalyzes the hydrolysis of ferric enterobactin (Fe-Ent).  Hydrolyzes Fe-Ent into three molecules of 2,3-dihydroxybenzoylserine (DHBS) still complexed with ferric iron.  Iron reduction is necessary to obtain complete release of the metal from DHBS.  It can hydrolyze salmochelin S4 (diglucosyl-C-Ent) but is not involved in iron acquisition by this siderophore.
What are the official names of this protein?
Iron(III) enterobactin esterase.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y472_MYCTO
Sequence: MAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHGRFLSMDEIAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQTTLIPNMIAALSADMDGFELTREIIRVYVETVAAQPEPYRFVMANSSASKSKVIADSERIIARMLAVMLRRRMQEAGMDTGGVEPWAYLIVGGVQLATHSWMSDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQV
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MT0489.
Protein: OBG_SHEPW
Sequence: MKFVDEATIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITYQFERFHNAERGKNGRGRDCTGHGGEDLVLKVPVGTRAVDAETEETLGDLTTHGQKMLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLRLELMLLADVGLLGMPNAGKSTFIRSVSKAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRVLLHILDIEPIDGSNPVDSARAIVGELEKHSPKLAGKPRWLVINKADLMLEEELQEKIDKVVEELAWDGEVFTISAYNREGTAELALKLLDFIDTLPPEEEVDVEAEVEFKWDNYHQNANESVNEDYDDDLDDDDYDDDDYDVEVIYQR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU2_SERP5
Sequence: MSKEKFERSKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGSARAFDQIDNAPEEKARGITINTSHVEYDTPSRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPFIIVFMNKCDMVDDEELLELVEMEVRELLSAYDFPGDDLPVVRGSALKALEGEAEWEAKIIELAGYLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIKDTVKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREDIERGQVLAKPGSIKPHTKFDSEVYILSKEEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNVNMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.