PharMolix/UniProtQA huggingface dataset:
Protein: AB17B_MOUSE
Sequence: MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLMCDESGSRWTLHLSERADWQYSSREKDAIECFMTRTSKGNRIACMFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRINCNIFSYDYSGYGASSGKPTEKNLYADVEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLERLKQFVSQELVNL
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (PubMed:27307232).  Has depalmitoylating activity towards DLG4/PSD95 (PubMed:27307232).  Has depalmitoylating activity towards GAP43 (PubMed:27307232).  Has depalmitoylating activity towards MAP6 (PubMed:28521134).  Has depalmitoylating activity towards NRAS (By similarity).
What are the official names of this protein?
Alpha/beta hydrolase domain-containing protein 17B, Abhydrolase domain-containing protein 17B.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD17 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendritic spine. Postsynaptic density membrane.
Protein: AED3_ARATH
Sequence: MASSSLHFFFFLTLLLPFTFTTATRDTCATAAPDGSDDLSIIPINAKCSPFAPTHVSASVIDTVLHMASSDSHRLTYLSSLVAGKPKPTSVPVASGNQLHIGNYVVRAKLGTPPQLMFMVLDTSNDAVWLPCSGCSGCSNASTSFNTNSSSTYSTVSCSTAQCTQARGLTCPSSSPQPSVCSFNQSYGGDSSFSASLVQDTLTLAPDVIPNFSFGCINSASGNSLPPQGLMGLGRGPMSLVSQTTSLYSGVFSYCLPSFRSFYFSGSLKLGLLGQPKSIRYTPLLRNPRRPSLYYVNLTGVSVGSVQVPVDPVYLTFDANSGAGTIIDSGTVITRFAQPVYEAIRDEFRKQVNVSSFSTLGAFDTCFSADNENVAPKITLHMTSLDLKLPMENTLIHSSAGTLTCLSMAGIRQNANAVLNVIANLQQQNLRILFDVPNSRIGIAPEPCN
What are the official names of this protein?
Aspartyl protease AED3, Apoplastic EDS1-dependent protein 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: PEPC_RHIFE
Sequence: MKWMVVVLLCLQLLEAKVVKVPLKKLKSLRETMKEKGLLEEFLKNHKYDPAQKYRYTDFSVAYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQTQACTGHTRFNPSQSSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGMAYPSLAMGGATTALQGMLQEGALTSPVFSFYLSNQQGSQNGGAVIFGGVDNSLYQGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSQGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDQYGQFFVNCNYIQNLPTFTFIINGVQFPLPPSSYILNNNGYCTVGVEPTYLPSQNGQPLWILGDVFLRSYYSVYDMGNNRVGFATAA
What is the function of this protein?
Hydrolyzes a variety of proteins.
What are the official names of this protein?
Gastricsin, Pepsinogen C.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAAR3_HUMAN
Sequence: MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVLSEADVSGMQSYKILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKGAVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYFNSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH
What are the official names of this protein?
Putative trace amine-associated receptor 3, TaR-3, Trace amine receptor 3, hTaar3, G-protein coupled receptor 57.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASHWN_CHICK
Sequence: MAAQGRGRVGGGKEERVSARSDSELLLHPELLSEEFLLLTLEQKNILVKNDVKMDKDGLTDLYIQHAIPLPQRDLPKSRWGKMMEKKRKQNEPKSENKSVTAVGGLRKRPLIVFDGSSTSTSIKVKKTENGATDRLKPPPAGSITNTVRRLSAPSNASTYISASSLSEDAKLEVRNNEAKQNNISKTNSSVLVNLKTHPLSPVAGTTVVKLKRSVPKDESDLPNDLKPTEAKKKIQHCTWP
What are the official names of this protein?
Ashwin.
What is the protein family that this protein belongs to?
Belongs to the ashwin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXS_BACC4
Sequence: MTNVTGTERVKRGMAEMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPADIRAAGGVSRMADPTIVEEVMGAVSIPVMAKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKRDYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVEAVRHMRQVNAEIRQVASLREDELMTYAKNTGAPYEVLLEIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSENPEKFARAIVEATTHYEDYELIASLSKGLGNAMKGVEISTLLPEQRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: TILS_MYCPU
Sequence: MKLIAVSGGPDSMLLLDVFKHHDIVVAHVNYNKRNSSKRDQKIVEDYCFKNNIKLEILNLTDYEVKGNFHDWARKKRFDFFKLVYEKYNCDEILLAHHKDDFVETFLIQKNQKRKPLYWSIKSKNFNFGMNINRPFIHKYWKNQILKILDNKQIFFGQDETNKENIYLRNKIRNNLLNKEFLKRLIYIKILFLNFFKLRKIKKIEQDFNKWKEQNFDKQNFLKSKFQENLITIFISEKTNNSINLSRGKIQQIIKFINSEKNEKKFILNKEFYLVKAKKIIKVLKK
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_NEIG1
Sequence: MSELLDHVASCRLPTEWGVFTMHGFEEANGQEHVALTVGNCSDGNPVLTRIHSECLTGDALFSRKCDCGPQLEAAMRAVQAEGRGIIVYLRQEGRGIGLINKIRAYHLQEQGMDTVEANLALGLPVDARDFRLAQSIYEYLGIRSVKLLTNNPEKIQTLKDAGINVVERIPLHVGENLENERYLQTKADKLGHLMSE
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: RSMA_MYCTU
Sequence: MCCTSGCALTIRLLGRTEIRRLAKELDFRPRKSLGQNFVHDANTVRRVVAASGVSRSDLVLEVGPGLGSLTLALLDRGATVTAVEIDPLLASRLQQTVAEHSHSEVHRLTVVNRDVLALRREDLAAAPTAVVANLPYNVAVPALLHLLVEFPSIRVVTVMVQAEVAERLAAEPGSKEYGVPSVKLRFFGRVRRCGMVSPTVFWPIPRVYSGLVRIDRYETSPWPTDDAFRRRVFELVDIAFAQRRKTSRNAFVQWAGSGSESANRLLAASIDPARRGETLSIDDFVRLLRRSGGSDEATSTGRDARAPDISGHASAS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGD_SACEN
Sequence: MSSYPPHEVAQRLASGLLSFPVTHFRADLTFDEPAYREHIGWLGQFGAAGLFAAGGTGEFFSLTPAEVETVVSAAVREVPDGLPVIAPAGYGTAMAVELARAAERAGAHGILLLPPYLTEADQEGLAAHVRAVCAATGLGVILYSRANAVYTETTVARLAEDCPNLVGFKDGVGDIERMTRLYARLGDRLTYVGGLPTAETFALPYLELGVTTYSSAMFNFVPRFALDFYDAVRRRDHAEVRRRLNDFVLPYCDIRNRRAGYAVSIVKAGMKVIGRPAGPVRSPLTDLDDAELAMLADLVKSMPATGEA
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: HTPG_HELAH
Sequence: MSNQEYTFQTEINQLLDLMIHSMYSNKEIFLRELISNASDALDKLNYLMLTDEKLKGLKITPSIHLSFDSQKKTLTIKDNGIGMDKNDLIEHLGTIAKSGTKSFLSALSGDKKKDSALIGQFGVGFYSAFMVAGKIVVQTKKVTSEQAYAWVSDGKGKFEINECIKDEQGTEITLFLKDEDANFASRWEIDSIVKKYSEHIPFPIFLTYTDTKMEGEGDHKKEVKEEKCEQINQASALWKMNKSELKDKDYKEFYKSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSVAPFDMFRVDYKSGVKLYVKRVFITDDDKELLPSYLRFIKGVIDSEDLPLNVSREILQQNKILANIRSASVKKILGEIEKLSKDNENYHKFYEPFGKVLKEGLYGDFENKEKLLELLRFYSKDKEKLISLKEYKENLKENQKSIYYLLGENLDLLKASPILEKYAQKGYDVLLLSDEIDAFVMPSVNEYDKMPFRDASHSESLKELGLEEINDEVKNQFKDLIKAFEENLKDEIKGVELSSHLTSAVALIGDEQNAMMANLMRQMGQNMPESKKTLELNPNHAILQKLLKCEDKEQMSAFIWLLYDGAKLLEKGALKDAKSFNERLNSVLLKAL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP3_FRACC
Sequence: MLGGGAPRARHVLPNIVERTSRGEYSMDPYSKLLKERIVFLGVQIDDVSANDVMAQLLFLESEDPDRDISIYINSPGGSFTSLTAIYDTMQFVRPDISTICMGQAASAAAVLLAAGTPGKRFALENSRILIHQPSAQGEGQSSDIEIQAREILRVRALQETMLARHTGRTETEIRRDTERDKIFSADEAEEYGLIDEVIMSRKAARLLSARSA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 3, Endopeptidase Clp 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_VIBC3
Sequence: MSETATTNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFQALSHPDLYQGDAELGVKLSFDKDKNTLTISDNGIGMTRDEVIENLGTIAKSGTAEFFSKLSQEQSKNSQLIGQFGVGFYSAFIVADAVTVRTRAAGSAPADAVQWYSKGEGEYTVETINKESRGTDIILHLREEGKEFLSEWRLRDVISKYSDHIGIPVYIQTSVMDEEGKATEETKWEQINKAQALWTRAKSEVTDEEYKEFYKHVSHDFADPLVWSHNKVEGKNDYTSLLYIPAKAPWDLFNREHKHGLKLYVQRVFIMDDAAQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKITQSLRQACTKRVLTMLERMASNDADNYQKFWKEFGLVMKEGPAEDFANREKIASLLRFASTHIDSAEQTISLASYVERMKEGQDKIYYLTADSYTAAKNSPHLEQFKSKGIEVILMFDRIDEWLMNYLPEFEGKAFQSITKAGLDLSQFEDEAEKEKHKETEEQFKSVVERLKGYLGSRVKEVRTTFKLANTPAVVVTDDYEMGTQMAKLLAAAGQPVPEVKYILEVNPEHALVKRMADEADEQTFGRWAEVLLGQAMLAERGSMEDPSQFLGAVNQLLAPSH
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_CAMC1
Sequence: MKNSLQGAMTALITPFKNQKLDEASFEKLIKRQIKHGIDVVVPVGTTGESATLTHDEHRICIEIAVDACKGTNVKVLAGAGSNATHEAIGIAKFAQAHGAHGILSVAPYYNKPTQEGLYEHYKAIANSIEIPVLLYNVPGRVGVDILPATVFRLFKDCKNIYGIKEATGSIDRCVDLLAHEPDLVVISGEDAINYPILSNGGKGVISVTANLLPDQISQLTHLAMNEEYKKAKLINDNLYTINKTLFCESNPIPIKAAMYLAGLIDTLEYRLPLCKPSKENFKKIEEVIKNYEIKGF
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_ECOBW
Sequence: MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLYDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLKKVDIGTSHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_SYNE7
Sequence: MPQLSKSLSFDGRDIRLELGLFAPQAGGSVLISSGDTAVLVAATRSTAREGIDFLPLTVDYEERMYAAGRIPGGFLRREGRPPERATLTSRLIDRPLRPLFPSWLRDDLQVVATTLSMDETVPPDVLAVTGASIATLVAKIPFYGPMAAVRVGLVGDDFIINPTYREIEKGDLDLVVAGTPAGVIMVEAGANQLPEADVIEAIDFGYEAVQELIKAQQSLLAELGIEQILPEAPNADNTLENFVRDRASSGVQQVLQHFSFTKSERDAALDEVKASVVEAIAALPEEDPVRSVTAAEPKALGNTFKALTKTLMRQQILRDGVRVDGRKLDQVRPISSQVGLLPPRVHGSGLFQRGLTQVLSIATLGTPGDAQELDDLHPDTQKRYLHHYNMPPYSVGETRPMRSPGRREIGHGALAERALLPVLPSKEEFPYVIRVVSEVLSSNGSTSMGSVCGSTLALMDAGVPIKKPVSGAAMGLIREGDEYRVLTDIQGIEDFLGDMDFKVAGTDQGITALQMDMKIHGLPLEIIADAINQAKPARLHILNKMLEAIATPRADLSTYAPRLFRIQINPEQIGLVIGPGGKTIRSITEQTGAKIDIEDTGAVTISAVDADSALRAKSIIEGMTRTITAGDVYIGKVTRIIPIGAFVEFLPGKEGMIHISQIADYRVARVEDELTVGDEVVVKVREIDQKGRVNLTRKGIDPEEVSAARAAVEAS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H3Y1_HUMAN
Sequence: MARTKQTARKATAWQAPRKPLATKAAGKRAPPTGGIKKPHRYKPGTLALREIRKYQKSTQLLLRKLPFQRLVREIAQAISPDLRFQSAAIGALQEASEAYLVQLFEDTNLCAIHARRVTIMPRDMQLARRLRREGP
What is the function of this protein?
Primate-specific variant histone H3, which constitutes a core component of nucleosomes (PubMed:20819935, PubMed:27016736).  Histone H3. Y-containing nucleosomes accumulate around transcription start sites and have flexible DNA ends, suggesting that they form relaxed chromatin that allows transcription factor access (PubMed:27016736).  Histone H1 binds less efficiently to histone H3. Y-containing nucleosomes (PubMed:27016736).  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (Probable).
What are the official names of this protein?
Histone H3.Y, Histone H3.Y1.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Histone H3.Y-containing nucleosomes are depleted from repressive post-translational histone modifications (PubMed:28334823). Histone H3.Y-containing nucleosomes accumulate around transcription start sites (PubMed:27016736).
Protein: UFC1_DROVI
Sequence: MVDDSTRKTLSNIPLLQIRAGPREKDIWVQRLKEEYQALIKYVENNKQSGSDWFRLESNKEGTKWFGKCWYMHNLLKYEFDVEFDIPVTYPTTAPEIALPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGIAHAMALGLAPWLAVEIPDLIEKGVITYKDNC
What is the function of this protein?
E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: KIME_ARATH
Sequence: MEVKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLRFPLPSAENNDRLTLQLKDISLEFSWSLARIKEAIPYDSSTLCRSTPASCSEETLKSIAVLVEEQNLPKEKMWLSSGISTFLWLYTRIIGFNPATVVINSELPYGSGLGSSAALCVALTAALLASSISEKTRGNGWSSLDETNLELLNKWAFEGEKIIHGKPSGIDNTVSAYGNMIKFCSGEITRLQSNMPLRMLITNTRVGRNTKALVSGVSQRAVRHPDAMKSVFNAVDSISKELAAIIQSKDETSVTEKEERIKELMEMNQGLLLSMGVSHSSIEAVILTTVKHKLVSKLTGAGGGGCVLTLLPTGTVVDKVVEELESSGFQCFTALIGGNGAQICY
What is the function of this protein?
Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
What are the official names of this protein?
Mevalonate kinase, MK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_SYNAS
Sequence: MPIEFEQTFRNFLMEHQEKYNRTYHFLILMDSIITAAQRIELYYRTGALKGNLGMAGSINVQGESVMKMDDIANEIVLHYLAASNRVIQVVSEESDDIVDMNKDGGRYFVYFDPLDGSSNVAHGLPVGFLFGIAKRNLDGNMKGPEDFHLREGNDYIAAGMFVIPTGMFTLALRDAGCWRFHADETATYVKPMRMTLPDDPKKWELSFNSANTTVFSEKVQSWIQVNISKYKFRYIGALAGDFHRLLTNGGLFMYPAIVKHPDPKENRPQGKLRLLYEANVVAFMCREAGGDAIDETGTRIMEIKPAGHHQRTTLYVGSKPIIDELASLFKS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUND1_HUMAN
Sequence: MAAVEAAAEPVTVVAAVGPKAKDEEEEEEEPLPPCEAVRWAPVGAVAEARPGATAFLEEATAEEPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPASDEGDGLPGDRPWLRGEDQSEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLNEDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSPLQTGGGHCECKAGGKTGNGCSRTGSSRTPPGNSKTKAEDVKKVRETGLHLMRRALAVLQIFAVSQFGCATGQIPPTLWQRVQADRDYSPLLKRLEVSVDRVKQLALRQQPHDHVITSANLQDLSLGGKDELTMAVRKELTVAVRDLLAHGLYASSPGMSLVMAPIACLLPAFSSAPEAMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPVTGGTVVTPKQSLLTAIHMVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF
What is the function of this protein?
May play a role as p53/TP53 inhibitor and thus may have oncogenic activity.
What are the official names of this protein?
RUN domain-containing protein 1.
Protein: RS3_PARD8
Sequence: MGQKVNPISNRLGIIRGWDSNWYGGKNYGDTLLEDSKIRKYLNARLAKASVSRIVIERTLKLITITVCTSRPGIIIGKGGQEVDKLKEELKKITDKEVQINIFEVKRPELDAVIVANNIARQLEGKIAYRRAVKMAIASTMRMGAEGIKIQISGRLNGAEMARSEMYKEGRTPLHTLRADIDYALAEALTKVGLLGVKVWICRGEVYGKRDLAPSFTAAKETGRRNDNAGGNRDKNFKRKRANR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: COBW_SINSX
Sequence: MTTARANQGKIPATVITGFLGAGKTTMIRNLLQNADGKRIGLIINEFGDLGVDGDVLKGCGAEACTEDDIIELTNGCICCTVADDFIPTMTKLLERENRPDHIIIETSGLALPQPLIAAFNWPDIRSEVTVDGVVTVVDSAAVAAGRFADDHDKVDALRVEDDNLDHESPIEELFEDQLTAADLIVLNKTDLIDASGLKAVRDEVSSRTSRKPTMIEAKNGEVAAAILLGLGVGTESDIANRKSHHEMEHEAGEEHDHDEFDSFVVELGSIADPAAFIDRLKGVIAEHDVLRLKGFADVPGKPMRLLIQAVGARIDQYYDRAWGAGEKRGTRLVVIGLHDMDEAAVRAAITALV
What is the function of this protein?
Zinc chaperone that directly transfers zinc cofactor to target proteins, thereby activating them.  Zinc is transferred from the CXCC motif in the GTPase domain to the zinc binding site in target proteins in a process requiring GTP hydrolysis.
What are the official names of this protein?
Zinc chaperone CobW.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.
Protein: KAD_BACFN
Sequence: MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTELGKTAKGYIDQGQLIPDELMVDILASVFDSFKDSKGVIFDGFPRTIPQAEALKVMLKERGQDISVMLDLDVPEEELMTRLIKRGKESGRADDNEETIKKRLVVYNTQTSPLKEYYKGEGKYQHINGLGTMEGIFEDICKAVDTL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_GEOSW
Sequence: MNDPFIVALDFSSGKEVRTFLQPFSHTSLFVKVGMELYYQEGPAIIHSLKEQGHRIFLDLKLHDIPNTVKRAMQGLARLEVDLVNVHAAGGTRMMEAALEGLEAGTPNGARRPYCIAVTQLTSTSEQMLHNELWIGRTMEETVLHYAALAKQSGLDGVVCSAKEVPLIRKHCGEAFLTVTPGIRFADDEKNDQVRVVTPYEAKKLGASFIVIGRSITRAENPIAAYERLQQEWKGEEKK
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RL23_SHESR
Sequence: MIREERLLKVILAPHISEKSTVNAEKHNTVVFRVAIDATKAEIKAAVAKLFEVEVESVRTLVSKGKTKRTGGRVGRRSDWKKAYVTLAAGADIDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SPH15_ARATH
Sequence: MSRLIFFILVTAIYFVGNEACKEIEIVIKNTLGPSRILQYHCRSGNTNVGVQYLNFKGTRIIKFKDDGTERSRWNCLFRQGINMKFFTEVEAYRPDLKHPLCGKRYELSARMDAIYFKMDERPPQPLNKWRS
What are the official names of this protein?
S-protein homolog 15.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: YEJL_SALCH
Sequence: MPQLSRYSDEHVEQLLSELLSVLEKHKAPTDLSLMVLGNMVTNLINTSVAPAQRQAIANSFARALQSSISEDNAH
What are the official names of this protein?
UPF0352 protein YejL.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: RL2_BRUMB
Sequence: MALKHFNPITPGQRQLVIVDRSELYKGKPVKSLTEGLSKKGGRNNTGRITVRFQGGGHKRSYRFIDFKRRKLDVVGTVERLEYDPNRTAFIALIRYTDGELAYILAPQRLAVGDQVVAGNSVDVKPGNAMPLSSMPVGTIIHNVELKPGKGGQIARSAGTYAQLVGRDQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRSVWRGKRPHVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGKKTRSNKATDKFIMRSRHQRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PSMA3_STAA2
Sequence: MEFVAKLFKFFKDLLGKFLGNN
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 3 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: NUOK2_RHIE6
Sequence: MVPLWWFIVLGVVLFVIGAAGVLLRRNILVVLMSLELLLNSVNINFIAFGHYYDDFRGQIFAIFVIAITAAEVAVALGILVALVRNKSTLKVDDVTMLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 2, NADH dehydrogenase I subunit K 2, NDH-1 subunit K 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.