PharMolix/UniProtQA huggingface dataset:
Protein: TIPIN_CHICK
Sequence: MAMIDPLENNLFDLPDYENTEDETFPPLPPPTSPGRGDAEWAQANGDPDGNQQSETKDSSSAARKAVKRSIPKLDANRLVSERGLPALRHMFDNVKFKGKGHEAEDLKTLLRHMEHWAHRLFPKLQFDDFIDRVESLGNKKEVQTCLKRIRLDLPILHEDFTANEGGGGESNGLDMATEEVHSFSGNVGELDSLPGTTLTEEQQQRIKRNRQLALERRQAKMQCNSQSQHDELSPSYPEEELNIPVARDLTGALEDTQVTATNVAVTETEDRERELQCASEKQ
What is the function of this protein?
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.  Important for cell survival after DNA damage or replication stress.  May be required for the replication checkpoint induced by hydroxyurea or ultraviolet light (By similarity).
What are the official names of this protein?
TIMELESS-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the CSM3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL15_METRJ
Sequence: MKLNQISDNPGATKDRMRVGRGIGSGKGKTAGRGVKGQKARTGVAIKGFEGGQMPLHRRLPKRGFNNLYAQDLNEVNLGRIQEAVDAGKLDKAATVTVESLVAAGIIARPRDGVKLLGVGELTAKLSFEVTRASKSAVEAVEKAGGSVSVVYAQGASTRGGSEAATA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: LEP_RICCN
Sequence: MQTDNTKSNTNKTAKQEWGSFAFVICIALLIRILIMEPFNVPTGSMKATILENDYIFSTKYSYGYSNYSLSFFDFIPLFKGRIFAREPDRGDIVVFRPPNDMSVRYIKRLIGLPGDKIQLIDDVIYINDKKIERTEVGTYISEEGIKYLKFKETLPNGRTYFSYKLAPIYGVIYNDRYSNTDVFYVPEGQYFFLGDNRDQSNDSRVNLGFVPFENFIAKAQFIWFSTKITWWDNDIGVINLVLKLKPWIESVRLNRIFRNLYNTDA
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: DACD_SALTY
Sequence: MLLKRRLFIAASLFAMHLSPALAADAVSFAPQPPAIDAGAWVLMDYTTGQVLTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRISPDDIVTVGRDAWAKDNPVFVGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQPQFVAMMNSYVKKLNLQDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRNGLLWDKTMHIDGLKTGHTSGAGFNLIASAVDGQRRLIAVVMGAKSSKGREEQARKLLQWGQQNFATVQILHSGKKVGSERIWYGDKEKIALGTEQDFWMALPKAEIPHIKAKYVLDRKELEAPIAAHQQVGEIELYDRDKLIAQWPLVTLESVGKGGMFSRLSDYFQHKA
What is the function of this protein?
Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
What are the official names of this protein?
D-alanyl-D-alanine carboxypeptidase DacD, DD-carboxypeptidase, DD-peptidase, Penicillin-binding protein 6B, PBP-6B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S11 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space.
Protein: RSMI_NEIMA
Sequence: MFQKHLQKASDSVVGGTLYVVATPIGNLADITLRALAVLQKADIICAEDTRVTAQLLSAYGIQGKLVSVREHNERQMADKIVGYLSDGMVVAQVSDAGTPAVCDPGAKLARRVREVGFKVVPVVGASAVMAALSVAGVAGSDFYFNGFVPPKSGERRKLFAKWVRVAFPVVMFETPHRIGATLADMAELFPERRLMLAREITKTFETFLSGTVGEIQTALAADGNQSRGEMVLVLYPAQDEKHEGLSESAQNIMKILTAELPTKQAAELAAKITGEGKKALYDLALSWKNK
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6341_DICDI
Sequence: MMVSIIVPSLVKESSRESLLATTIDNSTLSTTPSPKLPTLEISGGSAKEIWTKIDQNTAPSTPSKILPKRLPSQSNLNNNNN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0279885.
Protein: VCOX_BPHC1
Sequence: MSKQNAICINIHMEQPYMTREEFAKKLDVSTRTIDRLRQQGVLKCIKMKNDEGEETERGLVLVDLVAIAVRNAKNAFQI
What is the function of this protein?
Accessory protein needed to activate excisive recombination.  Appears to serve the additional function of repressing the production of the lysogenic repressor.
What are the official names of this protein?
Regulatory protein cox.
What is the protein family that this protein belongs to?
To phage P22 cox.
Protein: CINAL_DICT6
Sequence: MRCEILSVGTELLLGDILNTNSQYLSRRLAELGIPVYFHTTVGDNPERLKKALEIAFSRSDMVIATGGLGPTQDDLTKEVSAEFFNKKLVLHEESLKRIKEFFEKRGLALTEGNIKQAYIVEGSRVIPNDWGTAPGIILEEGNKILILLPGPPKEMIPMFETYVVPYLLSFSSGIIHSRVLRVCGIGESFMEEKVKDLIKTQTNPTIAPYAKEGEAILRVTARADTKEEAEKMIERVVEEIRKRLGDYIYGEGETSLEEVVVDLLSKKSLTISIAESCTGGLISARLVNVPGVSKFFKGSLVAYDNEIKIRELNVPREIIEKYGAVSSQCAMKMAEGVAQKMGTDIGLSATGIAGPEGGTPEKPVGLVYIGLYIRGELSYKELRLSGDRNRIRLYTTINALDFLRRGLLNL
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: ATPE_BRUMB
Sequence: MAQAFQFELVSPERLLLSAQVTEVVIPGSEGYLTALAGHSPLMTTIMPGVVSVKLADGKTDSYVVFGGFADITPQGCTVLAESATHVDDIDPADIQHRIDHARKVLEDASSNEHRTKAEIFLHQLMTLQGAILPA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MOAC_SHESW
Sequence: MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPLMLTKVEVDLEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: IMDH_STRP8
Sequence: MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPFFLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMTSEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRGMGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGYVGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: MIND_SHIFL
Sequence: MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLRNLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGVAKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGILASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVLRASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG
What is the function of this protein?
ATPase required for the correct placement of the division site.  Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity).
What are the official names of this protein?
Septum site-determining protein MinD, Cell division inhibitor MinD.
What is the protein family that this protein belongs to?
Belongs to the ParA family. MinD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NU1M_NOTTY
Sequence: MFIMNLLLYIIPILLAVAFLTLIERKVLGYMQFRKGPNVVGPYGLLQPFADAVKLFTKEPLHPLSSSVLMYTLAPTLALTLALTIWTPLPMPYSLVDLNLGLLFILALSSLSVYSILWSGWASNSKYPLAGALRAVAQTISYEVTLAIILLSIMMINGSFTLKNLIITQENMWLIVPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYTAGPFAMFFLAEYANIIIMNALTTMLFLGPSFNQDFTHVNTFTFMTKMMILTLTFLWVRASYPRFRYDQLMQLLWKNFLPMTLALCLWFISIPMALACVPPQI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YCIU_SALTI
Sequence: MEMDLNNRLTEDETLEQAYDIFLELAADNLDPADIILFNLQFEERGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADTEDGEINDIFARVLLCREKDHKLCHILWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: VAB2_YEAS7
Sequence: MVADLTKGILKWKSRIEFDAVGSSSYYEELKGLPPLASHKKLTQAAIFNSTKYELLQVKKDILSIYEVVSRDIDEERNQMQQIELQLKKSLKKVEHSYKNVLKQRASTNCINGNDRLLANAEKKIGSLNEELACVNDIVSDIVNNLTALNANLPKKAQLLKDDSINVAHYPLLFDFLHKSCPKSIIATSEASIHENASPSPLLEHDELPAESINSFYGENELQSDSLAPLQTHDDNISSCKKILPPKFNTTSGPSIETNFENISADGLTYTKCSLKNSISLT
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit VAB2, BLOC-1 subunit VAB2, VAC8-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the VAB2 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Vacuole. Cytoplasm.
Protein: PROF_CANAX
Sequence: MSWQAYIDNLIANGKVDKAALYSRAGDALWAQSGSFELQQPEITEIAKGFDSAEGLQTSGLHVQGQKYFLLRADDRSIYGKHEAEGVICVRTKQTILIAHYPSGVQPGEATTLVEKLADYLINVGY
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ZSC22_HUMAN
Sequence: MAIPKHSLSPVPWEEDSFLQVKVEEEEEASLSQGGESSHDHIAHSEAARLRFRHFRYEEASGPHEALAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPPEIQAWVGAQSPKSGEEAAVLVEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEPEGSSERSGLSGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSAWPNLTSQEKPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECGKAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQRIHTGEKPYKCGECGKTFSRSTHLTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLRIHSGEKPYQCKVCPKAFAQSSSLIEHQRIHTGEKPYKCSDCGKAFSRSSALMVHLRIHITVLQ
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 22, Krueppel-related zinc finger protein 2, Protein HKR2, Zinc finger protein 50.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLD_BACHK
Sequence: MVAVIIKGNEVAEKKRAQLKEEVVKLKEQGIVPGLAVILVGEDPASRSYVKGKEKGCEQVGIYSELIEFPETITEERLLAEIDRLNGDDRINGILVQLPLPKHIEEKAIIERISPEKDVDGFHPISVGRMMTGQDTFLPCTPHGIVELVKETNLDISGKHVVVIGRSNIVGKPVGQLFLNENATVTYCHSKTQNMKELTKLADILIVAVGRPKMVTADYIKEGAVVIDVGVNRLETGKLCGDVDFDNVLDVAGYITPVPKGVGPMTITMLLHNTVESAKRAGVVCK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SECA2_MYCTA
Sequence: MNVHGCPRIAACRCTDTHPRGRPAFAYRWFVPKTTRAQPGRLSSRFWRLLGASTEKNRSRSLADVTASAEYDKEAADLSDEKLRKAAGLLNLDDLAESADIPQFLAIAREAAERRTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLDAMGLTVGWITADSTPDERRTAYDRDVTYASVNEIGFDVLRDQLVTDVNDLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRETPRLEIIRLVAELVGDKDADEYFATDSDNRNVHLTEHGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYQLGVSPIPPNKPNIREDEADRVYITTAAKNDGIVEHITEVHQRGQPVLVGTRDVAESEELHERLVRRGVPAVVLNAKNDAEEARVIAEAGKYGAVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVVAANLDHNKLPMATDENGRIVSPRTGSLLDHAQRVAEGRLLDVHANTWRYNQLIAQQRAIIVERRNTLLRTVTAREELAELAPKRYEELSDKVSEERLETICRQIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIEAAQQTFETANVLDHEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSALSLPGVFR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: Y418_RHOPT
Sequence: MAEAWRYSAQGVAVAVRVTPRGGRDDIDGLETLSDGRPVVKVRVRAIADGGEANRAVTELLAKAVGVPKRNVRLLSGATSRQKQIAIDGDPKQLGEALRRLVAAKPAE
What are the official names of this protein?
UPF0235 protein Rpal_0418.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RS15_ACHLI
Sequence: MALTKDSKKAIVEKFARFAGDTGSPEVQVAILTHEINELNEHLQTHIHDFHSKRGLFMKIGRRRNLLKYLREQDAQRYAALINELGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: EFTS_BRUME
Sequence: MSISASLVKELRDLTGAGMMDCKAALAATEGKIEAAVDWLRAKGIAKADKKAGRTAAEGLVGVAASGNKAVVVEVNSETDFVARNDAFQELVRKIAQAALSTDGSSEAVANANVDGKTVTEAAKDAVATIGENISFRRSAALSVPQGVVATYIHNGVADGLGKLGVLVAIETAGDAEAAQAFGRQVAMHVAAVNPLALTSADVNPEAAEREKAIFIDQARQSGKPDNIIEKMVEGRMRKFYEEVVLLSQAFVINPDLTVEAALKDAEKAIGAPAKITGFARIALGEGIEKEESDFAAEVAAAAKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDS5_CONLT
Sequence: MPKLEMMLLVLLILPLCYIDAVGPPPPWNMEDEIIEHWQKLHCHEISDLTPWILCSPEPLCGGKGCCAQGVCDCSGPACTCPPCL
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Lt28.5, Conotoxin Lt15.6a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CD177_MOUSE
Sequence: MNSIPVLTLLGVTALLPCVPALTCQKSSAQAVRNVAELPLRWWGAGEKTCEVSEGCQDLIMLLYNGPKVNLVIIKGCTEVEDQEPKVIWLRTGPGLSVVSYTRVCRHGDLCNDVNSTKILEELPTPTVPGSLRCPLCLSNDSCENAPEQVCPVGSTHCYDGVLRLRGDGIRTNLKVQGCMAQPDCNLLNGTQAIGTLYMSENCDLIGPQALDCNSGSLETVRNVSDLHLSWTTGWQTCEAGEGCYETVMLIQNGHEFHMVLTKGCTRDMNKKARLTRHRTGPGISIVSYVHVCRDRDFCNDLSTTDPLWTPPPDTELGTLRCRHCLSTGSCVSASELVCPAGSTHCYSGVLSLRGGGVISDLKVQGCISQSQPGCNLLNGTQTIGPVDVREDCGLQLDALKCQHGTLKTIQDISKLPLQWTAGQKICNVGEGCQDTLMLIENGEQVNLVLTKGCTTAKDQEAKVTEHRTGPGLSVTSYTRVCRKKDFCNDLSTTAPLWAPPPVTAPGTTRCPLCFSEQACENAPEQVCPAGSTHCYSGVLSLRGGGIISDLKVQGCMSQPGCNLLNGTQTIGPVDVSERCSPPSETTELSCYRGVMFELGNGFAEEPVKWTAPGSQVCAPDEICQETLLLIDVGQKSAFLGSKGCSSPGAQDNIGVSIFSRLPGMLVASYTKFCSSHLCNGADSSSVLLSILPRPDVPPPGDVQCPMCVELFGSCKSTDSVTCPRGATHCYKGDIALQGGGLTTRVSIQGCMAPPIKPLLGDSKTIGIFSAEESSNYRHEDDVTSAPSLAWTLRLSAWMLGLSALLSSLYAGICPLC
What is the function of this protein?
In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (By similarity).  In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (By similarity).  Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (By similarity).  However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo (PubMed:25359465).  Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils (By similarity).  By displaying PRTN3 at the neutrophil cell surface, may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis (By similarity).
What are the official names of this protein?
CD177 antigen.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type IV membrane protein.
Protein: SYA_THET2
Sequence: MRTAEIREKFLSFFEGKGHLRLPSFSLIPEDDPSLLFTSAGMAPLKPYFLGAKPIFGGREWRRVTTCQECLRVGDIENVGRTSRHNTYFEMLGNFSFGDYFKKEAILWAWEFLTEHLRLDPGRLWVTVFEDDDEAYEIWRDLVGVPEERIGRFGEDENYWPGGAITHGPNGPSGPCSEIFYDRGPAYGTPDETGPNTGSGDRFVEIWNLVFTQYDRQGPIPGPGILKPLPQKNIDTGMGLYRVAAILQDVEDFYRTDTFFPIIQEVARMSGRPYEGKTSVSHRVIADHVRAVVAALSDGATFSNTGRGYVIRRLLRRALRHGYLLGLSDPFLHRLAPLVAELLGDFYPEMRENLPAVEKQIRLEEERFLETLEGGLKRLDALLSGLKPGEVLPGKEAFRLYDTYGFPLDLTVEIAAERGYGVDTEGFQKAMEEQQSRSRAAMAFEREIFKKGAQVLEELYAERGATEFLGYNALEAEAEVLALLAGDQSLLEAGPGTEVQVVLDKTPFYAEGGGQIGDFGLLEWPGGRARVETTRKTERGIFLHKARVEEGVLRVGERVRAVVDPRRRDTERNHTATHLLHAALRAVLGPHVRQAGSLVAPDRLRFDFTHPEPLKPEELERVELLVNRWIMADFPVTWRYMPLEEARKEGAMALFGEKYGEVVRVVRVEGSPLEGLESKELCGGCHVRRTGEIGAFLIRSEEAVSAGVRRIEAVTGEEAIRFARGSLNRLKALAERLEVGEAALEERLEKLLAELKEKEREVESLKARLVQAALGGGGGASLEEKGGLRWTVAELPGLDAKALRQAADDLVARGADVALVLSGGQAVLKLSPKAQGMGLEAGALFRALAEKAGGRGGGKGALAQGGGLDPRKAREALPGLLP
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_HALHL
Sequence: MSQPRQTRTFVRREGRLTQGQQRALEGLWPQFGVDVPERGVIDLDGLFGRAAPRVLDIGFGDGEALVEMAAADPERDYLGVEVHRPGVGHCLLCAEQAGLDNLRVATVDAVELVRHHLPGPSLETVQIFFPDPWPKKRHHKRRIIQPAFLDLLAERLVPGGALHLATDWADYAEWMLDTLEADARFENTCGPRAFVPPPPPRPQTKFERRGLRKGHQVHDLIYRLRPDTAG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: PTH_WOLTR
Sequence: MHLIVGLGNPGSQYELTYHNIGFIIVDAICKHWNFQSFSKKADCLITSSVINDNKIMLMKPYSFMNNSGIPVARIRNFYKFSLDNVIVIHDDADLEPGRIKIKKGGGSAGHNGLKSIDSSIGNDYWRLRFGIGRSDSQRSLADYVLSKFSNLDDVIPLVERIAQNIHLMLQGNNIAFTNSIV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGE_BACCA
Sequence: MAFFQKLTGQEQVNRDLLLLLCIGGFYTLGVSLSNTF
What are the official names of this protein?
Uncharacterized protein in sodM 3'region, ORFB.
Protein: METK2_BETVU
Sequence: METFLFTSESVNEGHPDKLCDQVSDAVLDACLAQDPESKVACETCTKTNMVMVFGEITTKAEVDYEKIVRDTCRSIGFTSDDVGLDADKCKVLVNIEQQSPDIAQGVHGHLTKRPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGACAWLRPDGKTQVTVEYYNDNGAMVPVRVHTVLISTQHDETVSNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVANGLARRAIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKETFDFRPGMMSINLDLKRGGNGRFQKTAAYGHFGRDDPDFTWEVVKPLKWEKIPA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate (By similarity).  May be involved in the synthesis of betain in response to abiotic stress such as high salinity (Ref. 1).
What are the official names of this protein?
S-adenosylmethionine synthase 2, AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_SYNWW
Sequence: MVMTDPVADFLTRIRNGNMVMHETVEVPGSRIKLSIARIMQEEGYIKDYEFVEDGKQGIIRIYLKYGPDKKKVITGIKRISKPGLRVYVKKDEIPRVLGGLGTAVISTSKGLMTDKNARKQGLGGEVICYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: DCYD_ECOHS
Sequence: MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTPMAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLLPESELIGVTVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLARFEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.