PharMolix/UniProtQA huggingface dataset:
Protein: NVFG_ASPN1
Sequence: MTQGKHCVPQGSTILVTGANGYLASAITKLLLELGYKVRGTVRAPKPWLNHYFEERYGSGNFETVIITDFQDTDTWDQALEGISGIAHVAHDMAWSSDPNIAVRGPVKAILNILDIASKHDSVKRIVLTSTIGAAPCIDINGNPATTPVNDDDWNDFAVEAAWSDSTPEEQRVYINHCAAKVEGDRKALQWVQDNQPGFDVNIVMPGFSVGRILHASITGQSMREIVGLLQGKPTKMFEFVPPWFINTEDVARLHVIALLKPEVSSQRIFACASPFTWKEVVSILRELDPSNTLIPDAPDENRRPCHVIPATEAERLIQDFFGRNGFTSLRDSLASAVTKSA
What is the function of this protein?
Ketoreductase; part of the gene cluster that mediates the biosynthesis of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety (PubMed:29968715).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase nvfA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (PubMed:29968715).  DMOA is then converted to farnesyl-DMOA by the farnesyltransferase nvfB (PubMed:29968715).  Epoxydation by FAD-dependent monooxygenase nvfK, followed by a protonation-initiated cyclization catalyzed by the terpene cyclase nvfL leads to the production of asnavolin H (PubMed:29968715).  The short chain dehydrogenase nvfC then as a 3-OH dehydrogenase of asnovolin H to yield chemesin D (PubMed:29968715).  There are two branches to synthesize asnovolin A from chemesin D (PubMed:29968715).  In one branch, chemesin D undergoes Baeyer-Villiger oxidation by nvfH, methylation by nvfJ, and enoyl reduction by the nvfM D enoylreductase that reduces the double bond between C-5'and C-6', to form respectively asnovolin I, asnovolin K, and asnovolin A (PubMed:29968715).  In the other branch, the methylation precedes the Baeyer-Villiger oxidation and the enoyl reduction to yield asnovolin A via the asnovolin J intermediate (PubMed:29968715).  Asnovolin A is further converted to fumigatonoid A by the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfI that catalyzes an endoperoxidation reaction (PubMed:29968715).  The alpha/beta hydrolase nvfD then acts as an epimerase that converts fumigatonoid A to its C-5' epimer, which then undergoes spontaneous or nvfD-catalyzed lactonization (PubMed:29968715).  The following step utilizes the ketoreductase nvfG to produce fumigatonoid B (PubMed:29968715).  The dioxygenase nvfE further converts fumigatonoid B into fumigatonoid C (PubMed:29968715).  Finally the Fe(II)/2-oxoglutarate-dependent dioxygenase nvfF catalyzes two rounds of oxidation to transform fumigatonoid C into the end product, novofumigatonin A (PubMed:29968715).
What are the official names of this protein?
Ketoreductase nvfG, Novofumigatonin biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: SYV_GEOKA
Sequence: MAQHEVSMPPKYDHRAVEAGRYEWWLKGKFFEATGDPNKRPFTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDVLWLPGMDHAGIATQAKVEEKLRQQGLSRYDLGREKFLEETWKWKEEYAGHIRSQWAKLGLGLDYTRERFTLDEGLSKAVREVFVSLYRKGLIYRGEYIINWDPVTKTALSDIEVVYKEVKGALYHLRYPLADGSGCIEVATTRPETMLGDTAVAVHPDDERYKHLIGKMVKLPIVGREIPIIADEYVDMEFGSGAVKITPAHDPNDFEIGNRHNLPRILVMNEDGTMNENAMQYQGLDRFECRKQIVRDLQEQGVLFKIEEHVHSVGHSERSGAVVEPYLSTQWFVKMKPLAEAAIKLQQTDEKVQFVPDRFEKTYLHWLENIRDWCISRQLWWGHRIPAWYHKETGEIYVDHEPPKDIENWEQDPDVLDTWFSSALWPFSTMGWPDTESPDYKRYYPTDVLVTGYDIIFFWVSRMIFQGLEFTGKRPFKDVLIHGLVRDAQGRKMSKSLGNGVDPMDVIDQYGADALRYFLATGSSPGQDLRFSTEKVEATWNFANKIWNASRFALMNMGGMTYEELDLSGEKTVADHWILTRLNETIETVTKLAEKYEFGEVGRTLYNFIWDDLCDWYIEMAKLPLYGADEAAKKTTRSVLAYVLDNTMRLLHPFMPFITEEIWQNLPHEGESITVAPWPQVRPELSNEEAAEEMRLLVDIIRAVRSVRAEVNTPPSKPIALYIKVKDEQVRAALMKNRAYLERFCNPSELLIDTNVPAPDKAMTAVVTGAELIMPLEGLINIEEEIKRLEKELDKWNKEVERVEKKLANEGFLAKAPAHVVEEERRKRQDYIEKREAVKARLAELKR
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYST_NEPOL
Sequence: MFDPKSLDSGSRSILTMKNRLVSWAWALTLMYMLVSLILPIGALLQKSSQESVSEFVSIATAPVAMSAYAVTLSSALIAALLNGVFGLLIAWVLVRYEFPGRRLLDAAVDLPFALPTSVAGLTLATVYSDQGWIGTWLSSLNIQVAFTRLGVMLAMLFVSFPFVVRTLQPVLQDMERELEEAAWSLGASPFNTFLRVLCPPLMPAMMTGIALAFSRAVGEYGSVVIVSGNIPFQDLIAPVLIFQRLEQYDYSGATVIGTVVLLISLTLLLAINWIQASNRKFLG
What is the function of this protein?
Part of the ABC transporter complex cysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Probable sulfate transport system permease protein cysT.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: THIC_HAHCH
Sequence: MGGTIDINKISKLSESAQVDALSTQPFPASKKIYAEGSRPDIRVAMREITLTPTPLQDGATEENAPLRVYDTSGPYTDPAVEIDVRRGLPRMREAWINDRADTEHLTGATSFYAKSREQNLSLDNLRFEHRHAPRKALAGGNVSQLHYARKGIITPEMEYIAIRENLALEQAEIENAMRSQHPGMNFGANTPRYITPEFVRQEVAAGRAVIPCNINHPEAEPMIIGRNFHVKVNANIGNSAVTSSIEEEVEKLVWATRWGADTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGVAEDLNWEVFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLAHHQENFLYTHFEEICEIMKAYDVSFSLGDGLRPGCIADANDEAQFSELRTLGELTEIAWKHDVQTIIEGPGHVPMHMIKENMEEQLKHCKEAPFYTLGPLITDISPGYDHFSSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKDDVKQGLIAYKIAAHAADLAKGHPGAQLRDNAMSKARFEFRWEDQFNIALDPDTARAYHDETLPKEGHKLAHFCSMCGPKFCSMKITQDVRDYSAKLEAEKAQAEGASQQEAEQGMQEMSQKYKDAGRRLYHEV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: AI5L5_ARATH
Sequence: MDGSMNLGNEPPGDGGGGGGLTRQGSIYSLTFDEFQSSVGKDFGSMNMDELLKNIWSAEETQAMASGVVPVLGGGQEGLQLQRQGSLTLPRTLSQKTVDQVWKDLSKVGSSGVGGSNLSQVAQAQSQSQSQRQQTLGEVTLEEFLVRAGVVREEAQVAARAQIAENNKGGYFGNDANTGFSVEFQQPSPRVVAAGVMGNLGAETANSLQVQGSSLPLNVNGARTTYQQSQQQQPIMPKQPGFGYGTQMGQLNSPGIRGGGLVGLGDQSLTNNVGFVQGASAAIPGALGVGAVSPVTPLSSEGIGKSNGDSSSLSPSPYMFNGGVRGRKSGTVEKVVERRQRRMIKNRESAARSRARKQAYTVELEAEVAKLKEENDELQRKQARIMEMQKNQETEMRNLLQGGPKKKLRRTESGPW
What is the function of this protein?
Involved in ABA and stress responses and acts as a positive component of glucose signal transduction.  Functions as transcriptional activator in the ABA-inducible expression of rd29B.  Binds specifically to the ABA-responsive element (ABRE) of the rd29B gene promoter.
What are the official names of this protein?
ABSCISIC ACID-INSENSITIVE 5-like protein 5, ABA-responsive element-binding protein 1, Abscisic acid responsive elements-binding factor 2, ABRE-binding factor 2, bZIP transcription factor 36, AtbZIP36.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ABI5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFP1_CHLMU
Sequence: MVLSSQLSVGMFISTKDGLYKVVSVSKVSGSKGDTFIKVALQAAGSDVVVERNFKAGQEVKEAQFEPRNLEYLYLEEDNYLFLDLGNYEKIYIPKEIMKENAMFLKAGVTISALVHEGIVFSMELPHFLELMVSKTDFPGDSLSLSGGAKKALLETGVEVLVPPFVEIGDVIKVDTRTCEYIQRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P 1, EF-P 1.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAGB6_HUMAN
Sequence: MPRGHKSKLRTCEKRQETNGQPQGLTGPQATAEKQEESHSSSSSSRACLGDCRRSSDASIPQESQGVSPTGSPDAVVSYSKSDVAANGQDEKSPSTSRDASVPQESQGASPTGSPDAGVSGSKYDVAANGQDEKSPSTSHDVSVPQESQGASPTGSPDAGVSGSKYDVAAEGEDEESVSASQKAIIFKRLSKDAVKKKACTLAQFLQKKFEKKESILKADMLKCVRREYKPYFPQILNRTSQHLVVAFGVELKEMDSSGESYTLVSKLGLPSEGILSGDNALPKSGLLMSLLVVIFMNGNCATEEEVWEFLGLLGIYDGILHSIYGDARKIITEDLVQDKYVVYRQVCNSDPPCYEFLWGPRAYAETTKMRVLRVLADSSNTSPGLYPHLYEDALIDEVERALRLRA
What are the official names of this protein?
Melanoma-associated antigen B6, Cancer/testis antigen 3.4, CT3.4, MAGE-B6 antigen.
Protein: RL29_MYCCT
Sequence: MAKSKMLDLRNLSVDELIKTNESKRAELFALKFQAAVGSLEQTHRIKEIKKEIARIELALSEKRLSGENTNKVIKADYNKAVEEAEKAGKEVRAKQRKFLEEQYGQQSQTKVNEADIQKAMQAAEQETVEPDTKGETK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ARLR_STAHJ
Sequence: MTNILIVEDEQNLARFLELELTHDNYSVDIEYEGQAGLDKALSNNYDLIILDLMLPNINGLEICRRVRQEQSTPIIIITAKSDTYDKVTGLDYGADDYIVKPFEIEELFARIRAVLRRQPQKDIIDINGIKIDVDAFNVTINGEQLDFTKTEYDLLYLLATNRNRVLQREQILDHVWGYDSEVETNVVDVYIRYLRNKLKPYGKDKTIETVRGVGYVIR
What is the function of this protein?
Member of the two-component regulatory system ArlS/ArlR.
What are the official names of this protein?
Response regulator ArlR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS25_DROME
Sequence: MPPKKDAKSSAKQPQKTQKKKEGSGGGKAKKKKWSKGKVRDKLNNQVLFDKATYEKLYKEVPAYKLITPSVVSERLKIRGSLAKRALIELREKGLIKQVVQHHSQVIYTRATKGDEA
What are the official names of this protein?
40S ribosomal protein S25.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: Q2OA_COMTE
Sequence: AKSDVAELKPR
What is the function of this protein?
Converts (3-methyl-)-quinoline to (3-methyl-)2-oxo-1,2-dihydroquinoline.
What are the official names of this protein?
Quinoline 2-oxidoreductase alpha chain.
Protein: CH602_CORGL
Sequence: MAKIIAFDEEARRGLEKGLNTLADAVKVTLGPKGRNVVLEKAWGAPTITNDGVTIAREIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGSNPMGIKRGIEKAVAQVTEKLLEAAKEVETEEQIAATAGISAADPAIGAQIAKAMYAVGGGKLNKDSVITVEESNTFGVELEVTEGMRFDKGYISGYFATDMERLEAVLEDPYILLVSGKISNIKDLLPLLEKVMQSGKPLLIISEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAQLQDIAVLTGGQVISEEVGLSLETADLPLLGQARKVVVTKDDTTIVDGAGSEAQIEGRVNQIRVEIENSDSDYDREKLNERLAKLAGGVAVLKVGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQAAHVLDNDLELSGDEATGVRIVREALTAPLKQIAANAGLEPGVVADKVSQLPQGEGLNAANGEYVDLMAAGINDPVKVTRSALQNAASIAALFLTTEAVVADKPQPAGAAGMPGADEMGGMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC1_BACAN
Sequence: MRYITAGESHGPQLTVILEGVPAGLTLAAEHINKELLRRQKGHGRGRRMQIEMDTVEIVSGVRHGMTLGSPITLIVKNDDFKHWTKVMGAEPISEKESKEMKRTITKPRPGHADLNGAIKYGHRDIRNVLERSSARETTVRVAAGAVAKQILKELGVEIAGHVLEIGGVKAKHISNLSIEEIQIITENSPVRCLDKTVEQEMMDAIDNAKSSGDSIGGIVEVIAEGMPIGVGSYVHYDRKLDAKLAGAIMSINAFKGAEIGVGFEAARQPGSKVHDEILWDEEQGYTRKTNNAGGLEGGMTTGMPIVVRGVMKPIPTLYKPLASVDIDTKEAFQASIERSDSCAVPAAGVVAESVVAWELAHALVEQFGKDRMELIQQNITQHNKYAKEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase 1, CS 1, 5-enolpyruvylshikimate-3-phosphate phospholyase 1.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TIG_LEVBA
Sequence: MAAKWEKKDNNQGELTFEIAPDKIKEGLDKAFQRTKKNLAVPGFRKGRVPRQIFNQMYGEEALYQDALNIVLPEAYDAAIKEAGIEPVDQPQVDVESMDKDQPWVLKAVVTVKPDVKLGEYKGLSVTKQNTRVYQKDIDAEIEKQRQQQAELVLKEDEAAAKGDTVVIDFDGYVDGKQFDGGKADNYSLELGSNSFIPGFEDQLVGHKAGEDVDVKVTFPADYQAEDLRDKEATFKVTIHEVKEKQLPELDDEFAKDVDEDVDSLEELEAKTKDRLKEQKVTAAHDAIEDEAISEAVDNAEIAAVPEAMLKDDIDRQMDQYLANMQQQGIEPKMYFQLTGTTEDDLRKQFADGAEKRIKTNLVLEAVVEAEKIEPSEDEVAAEVKDLASQYGMEESAVRSALSDDMLKHDIAIKSAVDLIADSAKQDKKKDAEDDE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ITIH3_BOVIN
Sequence: MALAQWPYLILALLSGLAVSGFPRNPSLLLGKRSLPGRAVDGIEVYSTKVNCKVTSRFAHNVVTTRAVNHANTAKEVSFDVELPKTAFITNFTLTIDGVTYPGKVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEITVDIFEPQGISTLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLKGDFIITYDVNRESPANVQIVNGYFVHFFAPQGLPVVPKSVVFVIDVSGSMHGRKMEQTKDALLKILEDVKQDDYLNFILFSGDVTTWKDSLVPATPENIQEASKFVMDIQDRGMTNINDALLRGISMLNKAREEHTVPERSTSIIIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGLARRIYEDSDANLQLQGFYEEVANPLLTGVEVEYPQNAILDLTQNSYQHFYDGSEIVVAGRLADEDMNSFKAAVKGHGAINDLTFTEEVDMKEMEKALQERDYIFGDYIERLWAYLTIEQLLDKRKNAQGEEKEILTAQALELSLKYHFVTPLTSMVVTKPEDNENQTAIANKPGEGPLDAEEVPSMAYLTSYQAPQTPYYYVDGDPHFIIQIPEKDDAICFNIDEDPGTVLRLIQDPVTGLTVNGQIIGEKTGRSDSQTRRTYFGKLGIASAQMDFRIEVTRENITLWNGDSLSTFSWLDTVMVTQDGLSVMINRKKNMVVSFGDGVTFVVVLHQVWKKEPAHHDFLGFYVVNSRGMSAQTHGLLGQFFHPFDFQVSDVHPGSDPTKPDATMVVKNHQLTVTRGSQKDYRKDISVGRNVACWFVHNNGQGLIDGIHRDYIVPNLF
What is the function of this protein?
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H3, ITI heavy chain H3, ITI-HC3, Inter-alpha-inhibitor heavy chain 3.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: SELO_HERAR
Sequence: MNAPIPHAVCHLNDMPLANSFASLPPAHYTALMPTPLPAPYLVCASASAAALIGLDFSDIDSAAFIETFTGNRIPDGSRPLSAVYSGHQFGVWAGQLGDGRAILLGDVPAPTMIPSGRLELQLKGAGLTPYSRMGDGRAVLRSSIREFLCSEAMAALGIPTTRALCVTGSDQIVLREQRETAAVATRMAQSFVRFGSFEHWFYNEKHDELKTLADYVIAQFYPQFKTAENPYKALLTEVTLRTAQMIAHWQAVGFMHGVMNTDNMSILGLTLDYGPFGFMEAFNATHICNHTDQQGRYSYARQPQIGEWNCYALGQTLLPLIGDVDETQNALRIYKPAYAEKFAELMRAKLGLQTQQPDDGKLFDALFAVLQGSHADFTLFFRRLGELRIGQAASREALRDLFLDRAAFDDWALQYELRLQLENSDDDARKLAMHAVNPKYVLRNYLAQIAIEKAQNKDFSEVAKLLQVLEKPFDEQPENEKYAALPPDWANDLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: MPH1_ASPCL
Sequence: MSDSDNGSADSFDDEIDDFVVTTPRQSAGAWMLATRKASYDKNIVTRRLESDSVNALGSDSFIDRDEEDELPSPDHALFEGIDFENVEKTSRYKVFVPKHSNYQENIFVTQLTQPPSPPEMIRGPRWKKPDPEPPTPKPPATMTIPASRADQYRDDEKEIEAAIAASLRSFEEENCGPTSAMVDKSSATRTAAVPSNAQKQHVADVPFDVDDIPDDAFDSDLSLSPPRSNSQAALRGPVQSQFSTNRPLGLRQSTLFGMTARASEASIPRGEQVFSPPDKNEAPTHHKLDEEALNTWIYPTNLGKTRDYQFNITQRGLFHNLLVALPTGLGKTFIAATIMLNWYRWTKSSQIIFVAPTKPLVSQQISACFGIAGIPRSQTTMLTGEAAPGIRAEEWKAKRVFFMTPQTLINDLKSGIADPKRIVLLVVDEAHRATGGYAYVEVVKFIKRYNKSFRVLALTATPGSTVESVQAVIDGLDIAKVEIRTEQSLDIREYVHARNTDVQTFQNSDEMVLCMDLFSRTLQPLVDQLCSLNAYWGKDPMALTPFGLTKARQQWMLSDAGRNANYGLKGKVNAIFTVLASLAHAIDLLKYHGITPFYRHLVHFRSNTDGQKGGKYQRQIVQDESFKKLMNHLQPWTKNPEFIGHPKLEYLKQVVLNHFMDAGEGSGADGNHTRSATRIMVFAHFRDSAEEIVRVLKRYEPLIRPHVFVGQSSAKGSEGMDQKTQLSIVQKFKKGDYNTIVATSIGEEGLDIGEVDLIVCYDSSASPIRMLQRMGRTGRKRAGNIVLLLMQGKEEESYIRAKDNYEKMQEMIASGTRFAFHDDTSPRILPPGIRPTADKKQIDIPVENTQADLPEPKRRARPPKRPPKKFHMPDDVETGFSKASSLTGNKGAKKTDKQTTIRKPTPEPVAIPALEEVLLTPSQQNDLERRYCHIGGTSPQFIRNPRVDAYPRLQSVPRPTRAVKHGALTSRMIGTLQKMHQVGADCESRYKDILALESSKRPEDSVLVQESARPRQNKKLSVGVSRPSKAQPPQTQSTLAPIREGLVDDGILEPTVPNELASLLGHQNPKPFYSSQISQDDLESDFDLPDFDTLINRNAERTTPRKRNRFVLGDDSDE
What is the function of this protein?
ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance.  Capable of unwinding D-loops.  Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair.  Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
What are the official names of this protein?
ATP-dependent DNA helicase mph1, FANCM-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTND_SYNP6
Sequence: MTVLTIYREDLPEQPLTQATDGAAEIAALLAQQGLRFERWPAQVELADDATPEQILAAYATEVDRVKTEGGYITVDAVSLRPDHPDRAALRQKFLAEHIHSEDEVRFFVAGQGLFSLHLGDHVYALLCTQNDWISVPAGTRHWFDMGSQPYFTALRFFNNPEGWVAQFTGSDIASQFPLLP
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: SYD_CITK8
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNVNADMATGEIEVLASDLTIINRADSLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWQEVKGVDLGDFPIMTFAEAERRYGSDKPDLRNPMELVDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLSRKQIDDYGNFIKIYGAKGLAYIKVTERAKGLEGINSPVAKFLNAEIVEAILDRTAAQDGDMIFFGADNKKVVADALGALRLKVGKDLNLTDEAKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDLTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHSGDMQQTVFGILGINEQEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPAALAELGIDVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSG1_CROS8
Sequence: MEYLPLFAQLKQRPVLVVGGGEVALRKIALLRRAGACVSVVAKKLHPELAALEQEGALRWLAQSFEPAQLDAVFLVIAATSDAALNRRVFDEANARQRLVNVVDDQPLCSFIFPSIVDRSPLIVAISSSGNAPVLARLLREKIESLLPASLGRMAEVAGGFRDRIKARIPTTDGRRRFWEKAFRGRFASLMAAGDTRAAEAVLEAELDAPQGPQGEIILVGAGPGDAGLLTLRGLQVMQQADVVLYDHLVSDGVLDLVRRDADRICVGKRAGAHAVAQHETNQMLIDFAREGKTVVRLKGGDPFIFGRGGEELEAAKAAGVPFQVVPGVTAASGATAYAGIPLTHRDYAQSAVFVTGHYKPDSEPFDWALLAKSRQTLAIYMGTMKAAEISQQLIAHGRDATTPVAVISRGTREDQRVLTGTLDTLNILAKDAPMPALLVVGEVVQLHQQLAWFQHSTDAENLRSSVVNLA
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: AGD10_ARATH
Sequence: MASENLNDKISVFKKLKAKSDNKICFDCNAKNPTWASVTYGIFLCIDCSAVHRSLGVHISFVRSTNLDSWSSEQLKMMIYGGNNRAQVFFKQYGWSDGGKTEAKYTSRAADLYKQILAKEVAKSKAEEELDLPPSPPDSTQVPNGLSSIKTSEALKESNTLKQQEKPDVVPVSPRISRSVKKPLGAKKTGKTGGLGARKLTTKSSGTLYDQKPEESVIIQATSPVSAKSARSSFSSRFDYADNVQNREDYMSPQVVSHVAPPKSSGFFEEELEMNGGRFQKKPITSSSKLQIQETDEARKKFTNAKSISSAQYFGNDNNSADLEAKSSLKKFSGSSAISSADLFGDGDGDFPLDLTAGDLLNRLSLQAQQDISSLKNMAEETKKKLGSVASSLWV
What is the function of this protein?
GTPase-activating protein (GAP) for ADP ribosylation factor (ARF).  Activates ARF1 and ARF2.  Required for female gametophyte development.  Involved in root hair and pollen tube growth.
What are the official names of this protein?
ADP-ribosylation factor GTPase-activating protein AGD10, ARF GAP AGD10, Protein ARF-GAP DOMAIN 10, AtAGD10, Protein MATERNAL EFFECT EMBRYO ARREST 28, Protein ROOT AND POLLEN ARFGAP.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: DTD_KINRD
Sequence: MRAVVQRVTRARVTVEGEVVGAVDGPGLLVLLGVTHDDGPAQVELIARKVAQLRILRGERAAADVGAPVLLVSQFTLYADTRKGRRPTWNAAAPGDVAQPLVDAVADALRGHGLPVETGRFGADMAVELVNDGPTTILLDA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_PHOV8
Sequence: MNFKEGEVLYFDKPLKWTSFAVVNKIRYHICRKLGVKKIKVGHAGTLDPLATGVMIICTGKATKRIEEFQYHTKEYIATLQLGATTPSFDLEKEIDATYPTEHITRELVEEALQRFIGRIEQIPPVFSACKVDGKRAYDLARKGEDVELKAKTLIIDEIELLECNLPEIKIRVVCSKGTYIRALARDIGEALNSGAHLTGLIRTRVGDVRLEDCLSVESFPEWLDQQEIEEVINE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.