PharMolix/UniProtQA huggingface dataset:
Protein: BTBD8_HUMAN
Sequence: MARCGEGSAAPMVLLGSAGVCSKGLQRKGPCERRRLKATVSEQLSQDLLRLLREEFHTDVTFSVGCTLFKAHKAVLLARVPDFYFHTIGQTSNSLTNQEPIAVENVEALEFRTFLQIIYSSNRNIKNYEEEILRKKIMEIGISQKQLDISFPKCENSSDCSLQKHEIPEDISDRDDDFISNDNYDLEPASELGEDLLKLYVKPCCPDIDIFVDGKRFKAHRAILSARSSYFAAMLSGCWAESSQEYVTLQGISHVELNVMMHFIYGGTLDIPDKTNVGQILNMADMYGLEGLKEVAIYILRRDYCNFFQKPVPRTLTSILECLIIAHSVGVESLFADCMKWIVKHFARFWSERSFANIPPEIQKSCLNMLIQSLNDKNAAFLLMESDRLIISLPRVKWTEAALTMASQLQEKCIAFIVDNFSKIIQSENFALLLQSQAMSSTADLLDTILKAIEENITTENSCSLLMALDTLLNSDSTKEMGFTCKIQALRDKLWIFLVQSFYAVRHTESWKLMSTDDQQKIQAAAFDKGDDRRLGKKPIFSSSQQRKQVSDSGDIKIKSWRGNNKKECWSYLSTNKKMKSDGLGASGHSSSTNRNSINKTLKQDDVKEKDGTKIASKITKELKTGGKNVSGKPKTVTKSKTENGDKARLENMSPRQVVERSATAAAAATGQKNLLNGKGVRNQEGQISGARPKVLTGNLNVQAKAKPLKKATGKDSPCLSIAGPSSRSTDSSMEFSISTECLDEPKENGSTEEEKPSGHKLSFCDSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSVKSSVSSRQSDENVAKLDHNTTTEKQAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQKPLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPNHKETDDCDAANICCHSVGSDNVNSKFYSTTALKYMVSNPNENSLNSNPVCDLDSTSAGQIHLISDRENQVGRKDTNKQSSIKCVEDVSLCNPERTNGTLNSAQEDKKSKVPVEGLTIPSKLSDESAMDEDKHATADSDVSSKCFSGQLSEKNSPKNMETSESPESHETPETPFVGHWNLSTGVLHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDDGSNDRGISKCGTMLCHDFLGRSSSDTSTPEELKIYDSNLRIEVKMKKQSNNDLFQVNSTSDDEIPRKRPEIWSRSAIVHSRERENIPRGSVQFAQEIDQVSSSADETEDERSEAENVAENFSISNPAPQQFQGIINLAFEDATENECREFSATKKFKRSVLLSVDECEELGSDEGEVHTPFQASVDSFSPSDVFDGISHEHHGRTCYSRFSRESEDNILECKQNKGNSVCKNESTVLDLSSIDSSRKNKQSVSATEKKNTIDVLSSRSRQLLREDKKVNNGSNVENDIQQRSKFLDSDVKSQERPCHLDLHQREPNSDIPKNSSTKSLDSFRSQVLPQEGPVKESHSTTTEKANIALSAGDIDDCDTLAQTRMYDHRPSKTLSPIYEMDVIEAFEQKVESETHVTDMDFEDDQHFAKQDWTLLKQLLSEQDSNLDVTNSVPEDLSLAQYLINQTLLLARDSSKPQGITHIDTLNRWSELTSPLDSSASITMASFSSEDCSPQGEWTILELETQH
What is the function of this protein?
Involved in clathrin-mediated endocytosis at the synapse.  Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission.
What are the official names of this protein?
BTB/POZ domain-containing protein 8, AP2-interacting clathrin-endocytosis, APache.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to nucleus in fetal cells.
Protein: TRPB_ACIAC
Sequence: MLSYQQPDASGHFGRYGGSFASETLTHALTELREAYARYQNDPEFLKEFHSELAHFVGRPSPIYHAARMSREMGGAQIFLKREDLNHTGAHKINNVIGQAMLARRMGKPRVIAETGAGQHGVATATICARYGLECVVYMGAEDVKRQSPNVYRMKLLGATVVPVESGSRTLKDALNEAMRDWVANVDNTFYIIGTVAGPHPYPMMVRDFQSVIGTECLAQMPGMLAGQRIAAEHPDAVIACVGGGSNAMGIFHPYIPHEKTRLIGVEAAGEGLDSGKHSASLQRGSAGVLHGNRTFILQDENGQITETHSISAGLDYPGVGPEHAWLQEIGRAEYVGITDREALDAFHYLCRTEGIIPALESSHAVAYAMQLARTLRTDQSILVNLSGRGDKDIGTVADLSGVDFYDRPSMRGHAVKGGPAA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: DAPA_NITMU
Sequence: MDNVAIKGSLVAIVTPMHENGELDLERFQSLIDFHVTEGTDGIVVVGTTGESPTVDFEEHHLLIKTAVEQAAGRVPVIAGTGANSTREAIDLSIYAKNAGADASLSVVPYYNKPTQEGLYQHFRAVAEAVDIPQILYNVPGRTVADIANDTVLRLAQIPNIVGIKDATGDIGRGFDLLCRAPEDFAIYSGDDASALALLLLGGHGVISVTANVAPKLMHEMCIAAFAGDLAAARAANRKLLRLHLDLFIEANPIPVKWAVAQMGLIGEGLRLPLTPLSNRYHQTLREAMSEAGIDLAISV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_ECOBW
Sequence: MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIRVVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGKPLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_ECO57
Sequence: MKPTTIASLQKCKQEKKRFATITAYDYSFAKLFAEEGLNVMLVGDSLGMTVQGHESTLPVTVEDIAYHTTAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEASDRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARAF_HUMAN
Sequence: MAAACGPGAAGYCLLLGLHLFLLTAGPALGWNDPDRMLLRDVKALTLHYDRYTTSRRLDPIPQLKCVGGTAGCDSYTPKVIQCQNKGWDGYDVQWECKTDLDIAYKFGKTVVSCEGYESSEDQYVLRGSCGLEYNLDYTELGLQKLKESGKQHGFASFSDYYYKWSSADSCNMSGLITIVVLLGIAFVVYKLFLSDGQYSPPPYSEYPPFSHRYQRFTNSAGPPPPGFKSEFTGPQNTGHGATSGFGSAFTGQQGYENSGPGFWTGLGTGGILGYLFGSNRAATPFSDSWYYPSYPPSYPGTWNRAYSPLHGGSGSYSVCSNSDTKTRTASGYGGTRRR
What is the function of this protein?
Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling.  In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.
What are the official names of this protein?
Store-operated calcium entry-associated regulatory factor, SARAF, SOCE-associated regulatory factor, HBV X-transactivated gene 3 protein, HBV XAg-transactivated protein 3, Protein FOAP-7, Transmembrane protein 66.
What is the protein family that this protein belongs to?
Belongs to the SARAF family.
Protein: LACA_ENTFA
Sequence: MRVILGSDLDGIKLKAEMKQYLLQEKVEVIDKSESASEDFIEATLAVAHEVLKDTESLGIVFDGYGAGSFMTAAKIKGMIVAELSDERSAYMAREHNNARMITVGAKIVGTELAKNIIKEFLTGHYAGGRHQIRVDMLNKMA
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: SAT_CENSY
Sequence: MSEGNIEPHGGRLISRLYSGDASGMEKAAISQELASDVENIADGIFSPLEGFLGRNDFEAVLEKGRLADGTAWTIPIVFDADAAEAARIKAAGDVLLEDPSGSKVAVLHAEEEYPFDKKAAAARVYGTDDAAHPGVSRMLSMKERLVGGRIDLVDRPEKTEIRRLRMSPVETRHAFAESGWKTTVAFQTRNPPHVAHEMLQKTSITTRDGVFVNPIVGRKKPGDFADEVIVKCYEEMIKHYYPENRCRLGTLHTEMRYAGPREAIHHGIMRQNYGCTHIIIGRDHAGVGKYYDPFAAHRIFDDYPDLGITPIFFPAFFYCRKCLTYTNPKACPHGEGEREQISGTALRDLIRAGKAPSEYILRPEVARIILEHPRPFID
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: RL33_THET8
Sequence: MASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVKI
What is the function of this protein?
Contacts the E site tRNA.
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TM41B_MOUSE
Sequence: MAKGRVADRSPTEMLHSTPAGDRAVRTQGSAAPGSKDHLNEKPCAEAGSARTSLLILVSIFSCAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLHQLTTAGEAVSWSSVFILMVLALLSILPAIFQKQLKQKFE
What is the function of this protein?
Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes.  Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine.  Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted by ATG2 (ATG2A or ATG2B) to mediate autophagosome assembly.  In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required (By similarity).  Required for normal motor neuron development (By similarity).
What are the official names of this protein?
Transmembrane protein 41B, Protein stasimon.
What is the protein family that this protein belongs to?
Belongs to the TMEM41 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endomembrane system. Note=Localized to specific membrane structures termed mitochondria- associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria.
Protein: LAEA_ASPFN
Sequence: MFGNGQTGQRLPAMASPPHDSYYSQSLASSRSRNNSDAMDIYAITDRDPPAREPSGYSQWYRNGSPSVNSIHSKSSEKQPFYEENGRMYHAYRKGVYMLPCDEQEQDRLDIFHKLFTVARVSDGLMYAPHPRNGRFLDLGCGTGIWAIDVANKYPDAFVVGVDLAPIQPSNHPKNCEFYAPFDFESPWAMGEDSWDLIHLQMGCGSVMGWPNLYRRIFAHLRPGAWFEQVEIDFEPRCDDRPLEGLAIRQWYQYLKQATQDAMRPINHNSRDTIRDLQEAGFTDIDHQMVGLPLNPWHQDEHERKVARWYNLAVSESIESLSMAPFSRIFNWDLDRIRRISSEVKSEAFNKEIHAYNILHIYQARKPAN
What is the function of this protein?
Methyltransferase that performs automethylation (By similarity).  No other methyl-accepting substrate has been identified yet (By similarity).  Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression.  Required for aflR expression and subsequent aflatoxin production (PubMed:18667168, PubMed:19411623, PubMed:22289775, PubMed:24040154).  Regulates negatively veA expression (PubMed:18667168, PubMed:19411623).  Controls conidiophore and conidial development (PubMed:22289775, PubMed:24040154).  Required for hydrophobin production which plays a role in cell surface hydrophobicity and host defense escape (PubMed:22289775).
What are the official names of this protein?
Secondary metabolism regulator laeA, Methyltransferase laeA, Velvet complex subunit laeA.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOI_PSEA8
Sequence: MIKEIINVVHGTFTQLRSLVMIFGHAFRKRDTLQYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETEDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEFKRQDLVYEKHDLLISGPGKNPDYNYYRVAGMAIAGKPKGAAQNEAEPINVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EP153_ASFP4
Sequence: MYFKKKYIGLIDKNCEKKILDDCTTIKICYILIGILIGTNMITLIYNFIFWDHYMTCNKKDKMFYCPKDWVGYNNVCYYFNNDSKNYTTATNSCKQLNSTLANNDTNLLNLTKVYHHDKLYWVNYSLNDNFSLSLRNSTYEKRSKYLPLLFICSK
What is the function of this protein?
Down-regulates MHC-I expression by impairing the appropriate configuration or presentation into the plasma membrane of the latter (By similarity).  Participates in viral hemadsorption, which may help viral spread (By similarity).  Reduces the transactivating activity of host TP53, thus inhibiting apoptosis (By similarity).  Non-essential for virus growth in swine macrophage cell cultures (PubMed:10573162).
What are the official names of this protein?
Lectin-like protein EP153R, pEP153R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus lectin-like protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: GLMM_ZYMMO
Sequence: MSRQYFGTDGIRGCTNKDPMTADVAMRVGQAAGAYFKRGLHRHRVLIGKDTRLSGYMVESALMAGFTSVGMDVVLVGPLPTPGVALLTRSMRADLGVMISASHNPFSDNGIKLFGPNGYKLSEEEEKAIEEAIDQPPLLAAPADIGRARRIDDAQGRYIHAVKSSFPESLRLDKLRLVLDCANGAAYQVAPAVLWELGAEVITLGVAPNGLNINDHCGSTDPSALQKKVLETRADLGIALDGDADRVIIVDEKGEIVDGDQIMALIATSAQKRNLLKGNTTVATVMSNLGLERYLSKLGIQLLRTQVGDRHVVEAMRAGGYTVGGEQSGHIILSYHTTTGDGLVAALQVLADLVQSDKKASELLHVFDPFPQLLKNVRYSSGQPLEDESVCEAISEAEESLKGKGRLLIRKSGTEPLIRVMAEAEDPDLVHQIVDHICETVRRAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NKG2D_PIG
Sequence: MGWIRDRRSPSSMEIRELHNRDVINRGAFKSRQKRTQTLITSKCGENPSPFFLARSIAIAMGIRFIVMVMIYSGMIINLLFNQEAPSPLKESYCGPCPKNWICYRNSCYQFSNESKTWLQSQASCRSQNSSLLKIYSREDQDFFKLVKSYHWMGLVQIPTNRSWQWEDGSILSPNQITMVEMQNGSCAVYGSSFKGYTENCLTLNTYICMKRTV
What is the function of this protein?
Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells.  Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity.  Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation.  Stimulates perforin-mediated elimination of ligand-expressing tumor cells.  Signaling involves calcium influx, culminating in the expression of TNF-alpha.  Participates in NK cell-mediated bone marrow graft rejection.  May play a regulatory role in differentiation and survival of NK cells.  Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins (By similarity).
What are the official names of this protein?
NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Colocalized with HCST on the cell surface.
Protein: RL19_BURM9
Sequence: MNLIAKLEQEEIERALAGKTIPEFAPGDTVIVNVNVVEGNRKRVQAYEGVVIAKRNRGLNSSFIVRKISSGEGVERTFQTYSPLLASIVVKRRGDVRRAKLYYLRERSGKSARIKEKLVSKDRAAAAQQ
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: FL3H_CALCH
Sequence: MAAPISLKWEEHSLHENKFVRDEDERPKVPYNTFSNEIPVISLAGIDGCRRAEICDEIVKACEDWGIFQVVDHGVDTKLLSDMTGLARDFFHLPTQEKLRFDMTGGKKGGFIVSSHLQGEAVQDWREIVTYFSYPIKARDYSRWPDKPNEWRAVTEEYSKVLMGLACKLLEVLSEAMGLEKEALTKACVDMDQKVVVNYYPKCPQPDLTLGLKRHTDPGTITLLLQDQVGGLQATRDGGESWITVKPVEGAFVVNLGDHGHYLSNGRFKNADHQAVVNSSTSRLSIATFQNPAPEAIVYPLKINEGEKSIMEEPMTFMEMYKKKMSTDLELARLKKLAKDKQQDLEVVKPIQNIFA
What is the function of this protein?
Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants.
What are the official names of this protein?
Naringenin,2-oxoglutarate 3-dioxygenase, FHT, Flavanone-3-hydroxylase, F3H.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: CPSF2_DICDI
Sequence: MASIIKFTALSGAKDESPPCYLLEIDDFCILLDCGLSYNLDFSLLEPLEKVAKKIDAVLLSHSDTTHIGGLPYVVGKYGLTGTIYGTTPVLKMGTMFLYDLYENKMSQEEFQQYSLDNIDSCFGEDRFKELSFSQHYSLSGKGKGISITPYLAGHTIGASVWKITKGTYSIVYAIDYNHRNEGHLDSLQLTSDILKPSLLITDSKGVDKTLAFKKTITRDQSLFEQINRNLRDGGNVLIPVDTAGRVLELLLCIENYWSKNKSLALYSVVFLGRFSFSVCQFARSQLEFMSSTASVKFEQNIENPFSFKHIKILSSLEELQELPDTNKVILTSSQDLETGFSRELFIQWCSDPKTLILFTQKIPKDSLADKLIKQYSTPNGRGKCIEIVQGSRVPLTGDELLQYEMEQAKQREEKRLEQLRKEQEEREERERLEEEEREQLLNATNQDQLQQLLQLQQQKERGIIDDSMVHMKNPFENDRFDLLDSEFKKQSMITMFPYFEKHLKWGEYGEEDDDLILRNQDKKVEEVTMEEDEIQEQEIPKKIITQTLRLPINCKIQTIDYEGCSDGRSIKAIIQQIAPTKLVLIRGSEQQSQSIENYVKENIRTKGIYIPSIGEQLDLTSDTNVYELLLKDSLVNTLKTSKILDYEVSYIQGKVDILDGSNVPVLDLIQSIPINNNNNNNNNNNNNNNNNNNNTTMMTTTTTTTNGHDESFIGDIKLSDLKQVLVNAGIQVQFDQGILNCGGLVYIWRDEDHGGNSIINVDGIISDEYYLIKELLYKQFQIV
What is the function of this protein?
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor 100 kDa subunit, CPSF 100 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FADR_ESCF3
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLAAANEVADHADAFAELDYSIFRGLAFASGNPIYGLIINGMKGLYTRTGRHYFANPEARSLALGFYHKLSELCRQGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLSIQGQ
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECF_PYRFU
Sequence: MPEVDNVIKEKLKLLVEMDPKKMIIYPLIVFGIAIIIIIANYVMTGSFVKEGIELRGGSVITLQGVNVSPDEIAKSIKEKTGIDVTVEKFSGVGGSGVRVYVSAGDDVNLVREALKEMFPDVEPQTVVIGPTFGEIVREQGIKAIVYAFIGMAIVVFLFFRVPVPSMTVVFSAFSDMIIAIALMNIFGIELSQATIAALLMLIGYSVDSNILLTTRLLRRKEFTVEEAYYSSLKTGFTMSTTTLGALASLWIFSTAQVIDDIASVLIFGLLADFMNTWILNAGVLRLYIAKREGKE
What is the function of this protein?
Involved in protein export.
What are the official names of this protein?
Protein-export membrane protein SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ODPA_CAEEL
Sequence: MSLFARQLQSLTASGIRTQQVRLASTEVSFHTKPCKLHKLDNGPNTSVTLNREDALKYYRDMQVIRRMESAAGNLYKEKKIRGFCHLYSGQEACAVGMKAAMTEGDAVITAYRCHGWTWLLGATVTEVLAELTGRVAGNVHGKGGSMHMYTKNFYGGNGIVGAQQPLGAGVALAMKYREQKNVCVTLYGDGAANQGQLFEATNMAKLWDLPVLFVCENNGFGMGTTAERSSASTEYYTRGDYVPGIWVDGMDILAVREATKWAKEYCDSGKGPLMMEMATYRYHGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDRIITSSLATEEELKAIDKEVRKEVDEALKIATSDGVLPPEALYADIYHNTPAQEIRGATIDETIVQPFKTSADVLKSIGRA
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial, PDHE1-A.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LYS1_CAEEL
Sequence: MLKLAFVTFLFALASARPQDVDSNRVVALPQDNFEVTDIGFEKIKAEPAPEVVNNDASYAYAVDISVPTTVSQMNCLKTSRYAAVFIRGFTPFGSGAFDTTSVTSIRNAYSAGLGIEVYMTPQPLSSLQGYQQLDALYNGLNGNGITIRSVWIQVTSPANWQKSATTNVNFLNSIISRAKQYGLTVGIYTNQYDWSQITGNWATLSSDVLLWYWHVLGGGVTGETPATFDDFRAFGSFKKASVKQFAQVESVCSLTVNRDVYVVGIPAAASSKNTDFFTQEDISSNNKKIVVGGVIGV
What is the function of this protein?
Involved in resistance to Gram-negative bacterium S. marcescens and to bacterium Gram-positive S. aureus infection.
What are the official names of this protein?
Lysozyme-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 25 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle lumen. Note=Localizes in vesicles in the apical region of intestinal cells.
Protein: RS8_NITOC
Sequence: MSMTDPISDMLTRVRNGQNAGKVEVSMPSSKLKVSIARVLKEEGYIEDCKVIADAKPTLVIRLKYYGGKPVIEDIHRASRPGLRMYKSRDKLPRIRGGLGIAIVSTSRGVMTDKTARSIGEGGEVLCYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: IAN12_ARATH
Sequence: MFSESLPEDKPVLEVALTELPMVAESLPEDGSGLEVTCDLRLEHKPARTLLLVGRSGNGKSATGNSILGRKAFKSKGRASGVTTACELQSSTLPNGQIINVIDTPGLFSLSPSTEFTCREILRCFSLTKEGIDAVLLVFSLKNRLTEEEKSALFALKILFGSKIVDYMIVVFTNEDSLEDDGDTFEEYLEDSPDFKEILEPCNDRKVLFRNRSNAPVSQKAKQVQELLNYVEEIARLNGKSYMADLSHEIRENETAFQIKQQEILEMKGLYTRQEMLQMKKDMEKSFENQQLRQMMERVETELRETKERLEQQLKEEKSARLELEKRAKEVEKRSSDVVKELNDEQAKRLESESRAKEAVKQSNGVVENLNKELARIKQMATDLQKSKQWCIIM
What are the official names of this protein?
Immune-associated nucleotide-binding protein 12, AtIAN12, AIG1-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
Protein: PNCB_ECO27
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLENKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLHQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: CARA_STRPN
Sequence: MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITDQSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLKAKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVSTKTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLSNGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVREIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDAAPGPHDASYLFDEFIEMMEVFKQSN
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.