PharMolix/UniProtQA huggingface dataset:
Protein: USPE_ECOL6
Sequence: MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDFSYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQEVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAVNLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYNDAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGISAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD
What is the function of this protein?
Required for resistance to DNA-damaging agents.
What are the official names of this protein?
Universal stress protein E.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECH17_MYCA1
Sequence: MAALNEFVSVVVSDGSRDAGLAMLLVSRPPTNALSRQVYREVIAAADELGRRDDVAAVILFGGHEIFSAGDDMPELRTLRGAEAETAARVRRDAIDAVAAIPKPTVAAITGYALGAGLTLALAADWRISGDNVKFGATEILAGLVPGGDALARLTRVAGASKAKELVFSGRFFDAEEALALGLIDEMVAPDDVYDAAAAWARRFLDGPRHALAAAKAGVDAVFELPRAERLAAGQRRYVEVFSAGQGGDAGADPHGG
What is the function of this protein?
Could possibly oxidize fatty acids using specific components.
What are the official names of this protein?
Probable enoyl-CoA hydratase echA17.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: UNG_MIMIV
Sequence: MSKKNVDPFSDSDSSSEPPSIFSSDNEENSDVDNSVIINDKNTKSDEADIKYMDEDESSDSESESESKKKSKKSKKSKKSKKSVTKKKNNLLVGNRIITEYILIDANNYHFKSWIECFPDCKVNLKLLLFRPEWFDFFKYVESKTYFPQLESKLSSYLEKRQRIVPYPELLFNTMNVLPPGKIKVVILGQDPYPGSCISGVPYAMGCSFSVPLNCPVPKSLANIYTNLIKFNHMRKAPKHGCLASWILQGTFMINSAFTTVLNESGVHARTWESFTADLIDYLTDNYDDLIFVAWGAHAHKLCQRVDPKKHYIITSSHPSPYSVSNTMTSMSYGPNPKKVTYPSFNSVDHFGKINEHLKSRNKKPIFWDL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Probable uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Protein: PANX1_PONAB
Sequence: MAIAHLATEYVFSDFLLKEPTEPKFKGLRLELAVDKMVTCIAVGLPLLLISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVYNRAIKAAKSARDLDMRDGACSVPGVTENLRQSLWEVSESHFKYPIVEQYLKTKKNSNNLIIKYISCRLLTLIIILLACIYLGYYFSLSSLSGEFVCSIKSGILRNDSTVPDQFQCKLIAVGIFQLLSVINLVVYVLLAPVVVYTLFVPFRQKTDVLKVYEILPTFDVLHFKSEGYNDLSLYNLFLEENISEVKSYKCLKVLENIKSSGQGIDPMLLLTNLGMIKMDVVDGKTAMSAETREEHGNQTAELQAMNIDGETKANNGEKNARQRLLNSSC
What is the function of this protein?
Structural component of the gap junctions and the hemichannels.  May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.
What are the official names of this protein?
Pannexin-1.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y857_STRE4
Sequence: MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPKFLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVSRYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFSSESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVMTHQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTADWPLHESHRDINRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SEQ_0857.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: BIOF_PARXL
Sequence: MHLLDTLAEGLKEIDARGLRRRRRTADTPCAAHMTVDGRAIIGFASNDYLGLAAHPQLIAAIAEGAQRYGAGSGGSHLLGGHSRAHAQLEDDLAEFVGGFVENARALYFSTGYMANLATLTALAGRGTTLFSDALNHASLIDGARLSRADVQIYPHCDTDALSAMLEASDADVKVIVSDTVFSMDGDIAPLPRLLELAEQHGAWLIVDDAHGFGVLGPQGRGAIAQAALRSPNLISIGTLGKAAGVSGAFVAAHETVIEWLVQRARPYIFTTASVPAAAHAVSASLRIIGGEEGDARRAHLQQLIGRTRAMLKATPWLPVDSHTAVQPLIIGANDATLEIAATLDRAGLWVPAIRPPTVPTGTSRLRISLSAAHSQADLDRLEAGLQQLGAKAA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: CLPP_BURL3
Sequence: MITRAELLDMLASNAPQGFEAQALGLVPIVVETSGRGERSYDIYSRLLKERLVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFIKPDVSTLCMGLAASMGAFLLASGAKGKRFALPNSRVMIHQPLGGARGQASDIEIQAREILYLKERLNQLLAQHTGQDVERIARDTDRDNFMSSEDAKAYGLIDQVLLKRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YH180_YEAST
Sequence: MPPARIELATFALQVQRSTTKLRRLKIQLCCISK
What are the official names of this protein?
Putative uncharacterized protein YHR180C-B.
Protein: THIL1_DICDI
Sequence: MISNLSKVLNSNVKRMYTTAKNLESVVIVSAVRTPIGSIGGSLSTIPGTKLSSITIEEAVKRAGIKPSDVDEAIIGNVISANLGQAPARQCALGAGLEQKTITTTINKVCSSGMKAIVFGAQSIALGHSKTVVAGGFESMSQVPYYADKMRFGAKYGNQTFIDGLVRDGLADAYNGSAMGVCGDDCADKYKITREQQDKFAVDSYLRALEAQKNGFFNDEIVQVPIVGRGGKVTYVVEDEEPKKVLFDKIPNLKPAFTPNGTVTPANASKLNDGASSVILMSESHAKELGLKPLARIIGYADAEQAPIEFPTAPALAIPKALKNAGINMSQVDLFEINEAFAVVGLANAKILDIDHNKLNVNGGAVALGHPIGSSGCRIVVTLTHLLQNKNLKYGVAAICNGGGGSTALVLEKL
What are the official names of this protein?
Probable acetyl-CoA acetyltransferase, Acetoacetyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: CB60B_GOSHI
Sequence: MMLPTKRPAPDHGDDERNEVMVPEPKRRTNLKKNIMGVGGLSFNKIVLNLEPMLRIWVHEAVEAAIRSSIHPSSRPSLNRIEASRGRRLQLRFVDKPPSTIFTGSKVEAENGNPIRIILVDATSQAMVSSGSLSSIKVEIVVLNGEFGTDERQDWTENEFNASVLREREGRRPLVTGDLNITLVDGVGTVDNVIFTDNSSWIRCRKFRLGARIVQRSAGEVTIREATSDAFMVKDHRGELYKKHYPPLLHDEVWRLERIAKDGAFHKRLAYKNVHTVKDFLRLLVTDPIALRNILGGGISNRVWETIIEHALSCVPDDDEWYTYHGTAQRVELLLNSIYNVVKVTFDGQDYLPVENLTFSQKLLVEDAKRQAYKNVWNLTPFDRRAIMGPSMPFTDLLPEPVGTSNLLLQQHDFSGTRPDMPLGLNQSSTSFSYEVENPKPLQGIEPLNPMLRNSSFRMEGIFPYNADNSFSFFADDGFGTNQDNTQAQMLSLTSATPAWAQGSGFIFTPDYETSSISFLSSFPSCNVNDRSIGETREVCPKNRWLKVRAVIQWKSISRGAAKRRRQHWLQHGICT
What is the function of this protein?
Transcription activator that binds DNA in a sequence-specific manner, likely 5'-GAAATTTTGG-3', to promote the expression of target genes (By similarity).  Required for pathogen resistance (PubMed:29757140).
What are the official names of this protein?
Calmodulin-binding protein 60 B, GhCBP60B.
What is the protein family that this protein belongs to?
Belongs to the plant ACBP60 protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RF3_STRPG
Sequence: MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLGIASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFTNNPFYEQVKEDIELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGNVVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSPKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVTLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_CHRSD
Sequence: MGRIIGIDLGTTNSCVAILDGGNAKVIENAEGARTTPSIIAYTDDGETLVGQAAKRQAVTNPSNTLYAIKRLIGRKFKDDVVQKDIKMVPYTIAEADNGDAWVEVKGNKLAPPQVSAEVLKKMKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAYGMDKARGDKTIAVYDLGGGTFDISIIEVADVDGETQFEVLATNGDTFLGGEDFDLKLIDYLVQQFKSDSGIDLSGDSLAMQRLKEAAEKAKIELSAAQQTEVNLPYITADNTGPKHLNVKVTRAKLESLVEELVQNSLAPCKTALSDAGLSASEIDEVILVGGQTRMPLVQKKVADFFGKDARKDVNPDEAVAVGAAIQGGVLGGDVKDVLLLDVTPLTLGIETLGGVMTPLIEKNTTIPTKKTQVFSTADDNQTAVTIHVLQGERKQSSGNKSLGRFDLADIPPAPRGVPQIEVAFDLDANGILNVSAKDKATGKEQSIVIKASGGLSDEEIDQMVKDAEAHEAEDKKFEELVQLRNQADGMVHAARKTLEEAGDKVDASEKEQIETAISELEEATKGDDQEHIQAKLDALTEASGNLAQKMYAEQGDAGAEGGEQPAGDGAQKKEDDVVDAEYEEVNDDQKKQ
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PROA_HELHP
Sequence: MQDMVAMLILAKRSARILERLSNEERNAVLESMADEIESQCEIICEANAKDMSVAEHLPLAMRKRLELNSIKVHSMADSMRDIAKLHCSVGQVIKSWKNKAGLEITQVSVPLGVIGVIYESRPNVTSDVSALCFKSGNVCVLKGGKEAFHSNVAILKALHSALEQHSLPKECVSMIEDTSREGILEFVKMDKYVDLLIPRGGEGLIEFVKHNATIPIIKHDKGVCHTYIHKSANLDMALNVVLNAKLSYPAACNACECILLDEVLVEGFLPKLLTKLREADVRVMFENEVWLKNWGIADDGLADFSKEWGDKILNLKVVNGIDEALEHIAHFGSAHSESIITQDEVIAQTFMREVDAACVYVNASTRFSDGGEFGFGAEVGISTSKLHARGPMGIESLLSYKYCITGNGQVR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPRA1_CAEBR
Sequence: MSVIFHENPGTSLGSVVSSDTNPSFNHTLSIETSPEWIDDLFSNVSFIDSTTHQVIRGFCRDVFVYRLPGGFRIRYWDAAILIPNLLFLLFLFLKCTSVIRKLQTGNSPVLRAFTLLVYVSTLVNIIRCVYSMTLSMTDGIEQTVDQTLWIIIKFFYLTAEFCALTFGLLFGHLDNGRSILIALLGTLLVSIPHTAVQVIVEMKIIDNSWLPLTYFDIESDGGFVFWVLSSATLALVYFFIMCLPLVCCQKYTKLPSNGSFFIYCMMMVTLNILQSMGAALILFKSSDGLCFVGVSTYVYFVLYPPIIYFTFLRRKLKTPPNNTSGLFMYRKHKDEQGSGDLPDSYYPRFSGLTSPSYDDLFDYDRDARFTHYDISTNEYVQHPHYNTYSTPLIMSTVETAESTVTTRTGSDDFAHHRDSMLSEPSTGTTTRHLKGLGPQGSLVFEEDPSSLRL
What are the official names of this protein?
Transmembrane protein adipocyte-associated 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0359 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OTSA_MYCLE
Sequence: MTSRGNHGSKTSSDKHLGDSDFVVVANRLPVDQVRLPDGTAIWKRSPGGLVTALEPLLRQRRGAWVGWPGVINDNVDLDLTIKSIVQDGLTLYPVRLNTHDVAEYYEGFSNATLWPLYHDVIVKPIYHCEWWERYVDVNRRFAETTSRTAAYGGTVWVQDYQLQLVPKMLRIMRPDLTIGFFLHIPFPPVELFMQIPWRTEIIEGLLGADLVGFHLTSGAQNFLFLSRHLLGANTSRGLVGVRSRFGEVQLKSHTVQVGAFPISIDSKEIDQATRDRNVRRRAREIRAELGNPRKILLGVDRLDYTKGIDVRLRAFAELLAEGRAKRDDTVLVQLATPSRERVESYKILRNDIERQVGHINGEYGEVGHPVVHYLHRPIPRDELIAFYVASDVMLVTPLRDGMNLVAKEYVACRNDLGGALVLSEFTGAAAELRQAYLVNPHDLEGVKDTIEAALNQLAEEARRRMRSLRRQVLAHDVDRWARSFLDALAEAPARDAT
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose and in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P).  Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Probably also able to use ADP-Glc, CDP-Glc, GDP-Glc and TDP-Glc as glucosyl donors.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: EFTS_HISS2
Sequence: MAEITAALVKELRERTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRIAAEGVIRVRIGSGFGVLVELNCETDFVAKDTGFLGLADEVADYALANKGTTIDTLATHFEDKRAALVAKIGENMTIRRVQYLEGDVIAQYLHGAKIGVLVAGSGSEEELRKVAMHVAASKPEFVNPEDVSAEVVEHERQIQIDIAINSGKPKEIAEKMVEGRMKKFTGEVSLTGQAFVMDPSVSVGDYLKSVNTSVTNFIRLEVGEGIEKVEEDFAAEVAKITGNNA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YG29_BPSP1
Sequence: MNQQMVLKIGGVVVDPQPVKVESKYTGELEVTRKKVVHRMLDIIIPVGLATKLTMALSPGALAAAGVDSADKIRRGFHDIIDVFTALAEPILWFYALTACVLIATKNKNAGWERLKNVGYAYAGIALLPTFFSFLRWVSSIVSSSITF
What are the official names of this protein?
Uncharacterized 16.2 kDa protein in gene 29 5'region.
Protein: PPK_RHOPR
Sequence: SPPFAPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Pyrokinin, Rhopr-PK, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MDEP_STAAN
Sequence: MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
What is the function of this protein?
Involved in multidrug efflux.
What are the official names of this protein?
Multidrug resistance efflux pump SepA, Antiseptic resistance protein SepA, Staphylococcal efflux pump A.
What is the protein family that this protein belongs to?
Belongs to the multidrug resistance efflux pump SepA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF2_NEIMF
Sequence: MSNTTVEQFAAELKRPVEDLLKQLKEAGVSKTGGGDSLTLDDKQLLNAYLTKKNGSNSSTISIRRTKTEVSTVDGVKVETRKRGRTVNIPSAEELAAQVKAAQTQAAPVRPEQTAEDAAKARAEAAARAEARAKAEAEAAKLKAAKAGNKAKPAAQKPTEAKAETAPVAAETKPAEESKAEKAQADKMPSKKPAEPKEKAAKPKHERNGKGKDAKKPAKPAAPAVPQPVVSAEEQAQRDEEARRAAALRAHQEALLKEKQERQARREAMKQQAEQQAKAAQEAKTGRQRPAKPAEKPQAAAPAVENKPVNPAKAKKEDRRNRDDEGQGRNAKGKGGKGGRDRNNARNGDDERVRGGKKGKKLKLEPNQHAFQAPTEPVVHEVLVPETITVADLAHKMAVKGVEVVKALMKMGMMVTINQSIDQDTALIVVEELGHIGKPAAADDPEAFLDEGAEAVEAEALPRPPVVTVMGHVDHGKTSLLDYIRRTKVVQGEAGGITQHIGAYHVETPRGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTIEAIAHAKAAGVPMVVAVNKIDKEAANPERIRQELTAHEVVPDEWGGDVQFIDVSAKKGLNIDALLEAVLLEAEVLELTAPVDAPAKGIIVEARLDKGRGAVATLLVQSGTLKKGDMLLAGTAFGKIRAMVDENGKSITEAGPSIPVEILGLSDVPNAGEDAMVLADEKKAREIALFRQGKYRDVRLAKQQAAKLENMFNNMGETQAQSLSVIIKADVQGSYEALAGSLKKLSTDEVKVNVLHSGVGGITESDVNLAIASGAFIIGFNVRADASSRKLAENENVEIRYYNIIYDAIDDVKAAMSGMLSPEEKEQVTGTVEIRQVISVSKVGNIAGCMVTDGVVKRDSHVRLIRNNVVIHTGELASLKRYKDDVKEVRMGFECGLMLKGYNEIMEGDQLECFDIVEVARSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIXC1_RAT
Sequence: MLACLTRGNLLDVLQEGFNEQQLQAYVAWVNAQLKKRPSVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPSNQQEMKSNVERVLQFVASKNIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSRTSVQSHQPHCATAVAQGAAAALADVCHDVSRSGRDVFRYRQRNASVDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIIPSEGIENRTDETGSPLSRDWRPGSPGTYLEATWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPVALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKDLGQKDRLLQQQQAKLEDALRKLSDASYQQVDLERELEQKDVLLAHRVKGDTDEVTNYNSHSSQRNGFVLPVAGRAATTATHRGPQSSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLIERLHVIETQKKQERKVRGRSPRNQASSEYRASWPPNSTLPHSQSSPAVSNTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGSHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEDHREN
What is the function of this protein?
Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2.  Regulates JNK activation by AXIN1 and DVL2.
What are the official names of this protein?
Dixin, Coiled-coil protein DIX1, Coiled-coil-DIX1, DIX domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DIXDC1 family.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm. Note=Colocalizes with gamma-tubulin at the centrosome, both during interphase and mitosis. Associated with actin stress fiber at the filament ends.
Protein: UCRI2_ARATH
Sequence: MLRVAGRRLFSVSQRSSTATSFVLSRDHTLSDGGNSSSASRSVPSADLSSFNSYHRSVIRGFASQVITQGNEIGFGSEVPATVEAVKTPNSKIVYDDHNHERYPPGDPSKRAFAYFVLSGGRFVYASVLRLLVLKLIVSMSASKDVLALASLEVDLGSIEPGTTVTVKWRGKPVFIRRRTEDDIKLANSVDVGSLRDPQEDSVRVKNPEWLIVVGVCTHLGCIPLPNAGDYGGWFCPCHGSHYDISGRIRKGPAPYNLEVPTYSFLEENKLLIG
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.  The Rieske protein is a catalytic core subunit containing a [2Fe-2S] iron-sulfur cluster.  It cycles between 2 conformational states during catalysis to transfer electrons from the quinol bound in the Q(0) site in cytochrome b to cytochrome c1.
What are the official names of this protein?
Cytochrome b-c1 complex subunit Rieske-2, mitochondrial, Complex III subunit 5-2, Rieske iron-sulfur protein 2, RISP2, Ubiquinol-cytochrome c reductase iron-sulfur subunit 2.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SK1_EUBPO
Sequence: EQFEDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, EubPo-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRF_ECOLU
Sequence: MTLTASSSSRAVTNSPVVVALDYHNRDAALAFVDKIDPRDCRLKVGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASGGARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLADLGVTLSPADYAERLAALTQKCGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALAAGVDYMVIGRPVTQSVDPAQTLKAINASLQRSA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: BLC1_ECOLX
Sequence: MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAVAAVLKKSESEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESRRDVLASAAKIVTNGL
What is the function of this protein?
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins.
What are the official names of this protein?
Beta-lactamase CTX-M-1, Beta-lactamase MEN-1, Cefotaximase 1.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: MUKB_SERP5
Sequence: MIERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLRAGVCYSTLDVLNSRHQRVVVGVRLQQVAGRDRKVDIKPFVIQGLPTAVQPTELLTQTVGERQARVLSLQELKDRVEEMEGVQFKQFNSITDYHSLMFDLGVIPKRLRSSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATSYVAADYMRHANERRIHLDGALALRNDLLGSRKQLAAEQYRHVEMARELAEQSGAESDLETDYQAASDHLNLVQTAMRQQEKIERYEGDLEELTYRLEEQNEVVAEASEQQAENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYQQALQALDRARTLCQLPELTAENAEHWLDTFQAREQEATEALLMLEQKLSVADAAHGQFEQAYQLVGKIAGQVSRSEAWQCARELLRDWPSQQHLAERVQPLRMRLSELEQRLRSQQDAERLLQEFCKRHGQQYQPDELDALQQELEERLESLSQGVSDAGERRMEMRQELEQIQQRIRELTTRAPIWLAAQDALSQLGEQSGEALESSQQVTEYMQQLLERERETTVERDEVAAGKRAVEAQIERLSQPGGAEDQRLVTLAERFGGVLLSEIYDDVTIDDAPYFSALYGPSRHAIVVPDLSLVREMLEGLEDCPEDLYLIEGDPQSFDDSVFAVEEQDRAVLVKTAERQWRYSRYPAVPLFGRAARENRLEILHAEREKLAERYATLSFDVQKTQRSHQAFSRFIGNHLAVAFDADPEAEIRGLNTRRGEIERALNNHEAQNQQQRQQYDQAKEGISALNRLTPLVSLLNDETLQDRVEEIREELEEAQDAARHIQQHGVSLTKLEPLLSVLQSDPQQHEQLQQDYTQAQSVQRQAKQQAFALIEVVQRRAHFSYTDSAGMQNANNDLNDKLRQRLEHAEAERTRAREQLRQYQTQFTQYSQVLASLKSSYDAKRDMLKELSQELVDIGVQADANAEARARTRRDELHAGLSTNRARRNQLEKQLTFCEAEMDSLQKKLRKLERDYYQLREQVVTAKAGWCAVMRLVKDNGVERRLHRRELAYMDGDELRSMSDKALGALRLAVSDNEHLRDVLRLSEDPKRPERKIQFYIAVYQHLRERIRQDIIRTDDPVEAIEQMEIELGRLTEELTAREQKLAISSKSVANIIRKTIQREQNRIRMLNQGLQAVSFGQVKSVRLNVNVREAHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLELEVEVFRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEEESRRLRGKDISPCRLLFLDEAARLDAKSIATLFELCDRLEMQLIIAAPENISPEKGTTYKLVRKVFQNHEHVHVVGLRGFANEPPVLGVTAAETP
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: FMA0_DICNO
Sequence: MKSLQKGFTLIELMIVVAIIGILAAFAIPAYNDYIARSQAAEGVSLADGLKVRIAENLQDGECKGPDADPQSGVVGNEDIGKYALAKIEGDYDASKTDAGAPNGCKVEITYGQGTAEGKISKLITGKKLVLDQLVNGSFIAGDGTDLADKFMPNAVKAKK
What is the function of this protein?
Major component of the type IV fimbriae that plays an essential role in twitching motility, natural transformation, and protease secretion.
What are the official names of this protein?
Type IV major fimbrial protein FimA, Pilin, Serogroup B1/AC20.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.