PharMolix/UniProtQA huggingface dataset:
Protein: 1A_CMVII
Sequence: MATSSFNINELVASHGDKGLLATALVDKTAHEQLEEQLQHQRRGRKVYIRNVLGVKDSEVIRNRYGGKYDLHLTQQEFAPHGLAGVLRLCETLDCLDSFPSSGLRQDLVLDFGGSWVTHYLRGHNVHCCSPCLGIRDKMRHAERLMNMRKIILNDPQQFDGRQPDFCTQPAEDCKVQAHFAISIHGGYDMGFRGLCEAMNAHGTTILKGTMMFDGAMMFDDQGVIPELNCQWRKIRSAFSETEDVTPLSGKLNSTVFSRVRKFKTMVAFDFINESTMSYVHDWENIKSFLTDQTYSYRGMTYGIERCVIHAGIMTYKIIGVPGMCPPELIRHCIWFPSIKDYVGLKIPASQDLVEWKTVRILMSTLRETEEIAMRCYNDKKAWMEQFKVILGVLSAKSSTIVINGMSMQSGERIDINDYHHIGFAILLHTKMKYEQLGKMYDMWNASSISKWFAALTRPLRVFFSSVVHALFPTLRPREEKEFLIKLSTFVTFNEECSFDGGEEWDVISSAAYVATQAVTDGKILAAQKAEKLAEKLAQPVIEVSDSPEASSQTPDDTAEVCGKEREVSELDSLSAQTRSPITRVAERATAMLEYAAYEKQLHDTTVSNLKRIWNMAGGDDKRNSLEGNLKFVFDTYFTVDPMVNIHFSTGRWMRPVPEGVVYSVGYNERGLGPKSDGELYIVNSECVICNSESLSTVTRSLQAPTGTISQVDGVAGCGKTTAIKSIFEPSTDMIVTANKKSAQDVRMALFKSSDSKEACTFVRTADSVLLNECPTVSRVLVDEVVLLHFGQLCAVMSKLKAVRAICFGDSEQIAFSSRDASFDMRFSKIIPDETSDADTTFRSPQDVVPLVRLMATKALPKGTHSKYTKWVSQSKVTRSVTSRAIVSVTLVDLDSSRFYITMTQADKASLISRAKEMNLPKTFWNERIKTVHESQGISEDHVTLVRLKSTKCDLFKQFSYCLVALTRHKVTFRYEYCGVLNGDLIAECVARA
What is the function of this protein?
Involved in the virus replication.  Contains a helicase domain and a methyltransferase domain.  The methyltransferase domain is probably involved in viral RNA capping.  Involved in the formation of ER membrane spherular invaginations in which RNA replication complexes form (By similarity).
What are the official names of this protein?
Replication protein 1a.
What is the protein family that this protein belongs to?
Belongs to the bromoviridae replication protein 1a family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: CAP9_ADECC
Sequence: MDPQQKGIVNTCFLTTRIPSWAGARQNVTGSDLGGKPVPSDVLESGRPLAAPRVRTLYEEQQLNMLTVNVILDDLKTQVAAMQNSVTAIQEELKDLKQRVAAR
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior and forms triskelion structures consisting of three molecules that stabilize three hexon trimers at the center of each icosahedral facet and fixes the peripentonal hexons.  Dispensable for assembly.  During virus entry, recruits the anterograde motor kinesin-1 to the capsid docked at the nuclear pore complex thereby subjecting the docked capsid to a pulling force.  The resulting tension leads to capsid disruption, dispersion of capsid fragments toward cell periphery and eventually viral DNA entry into the host nucleus.
What are the official names of this protein?
Hexon-interlacing protein, Protein IX.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-interlacing protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Located in the canyons between the hexons on the outer surface of the capsid. Forms a sort of hairnet on the outer side of the virion. Present in 240 copies per virion.
Protein: PYRR_STRA1
Sequence: MKRKEIIDDVTMKRAITRITYEIIERNKNLDNIVLAGIKTRGVFLAKRIQERLKQLENLDIPVGELDTKPFRDDMKVEVDTTTMPVDITDKDIILIDDVLYTGRTIRAAIDNLVSLGRPSRVSLAVLIDRGHRELPIRADYVGKNIPTSQFEEILVEVMEHDGYDRVSIIDPS
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: RECA_PSEPK
Sequence: MDDNKKRALAAALGQIERQFGKGAVMRMGDHERQGIPAISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAEAQKNGATCAFVDAEHALDPEYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDMHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKIVKNKVSPPFRQAEFQILYGKGIYRNGEIIDLGVSQGLVEKSGAWYAYQGNKIGQGKANAAKYLAENPAIGAEIEKQIREKLLKAGAAAEAGKAAAAEADADDMADADAGY
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTMCB_BACSU
Sequence: MQQQEQQQGGMKVKVQRFGSYLSGMIMPNIGAFIAWGIITALFIPAGWFPNEQLNTLVSPMITYLLPLLIAYTGGKMIYDHRGGVVGATAAIGVIVGSDIPMFLGAMIMGPLGGYLIKQTDKLFKDKVKQGFEMLINNFTAGIVGAALTILAFYAIGPVVLTLNKLLAAGVEVIVHANLLPVASVFVEPAKVLFLNNAINHGILSPIGIEQASQTGKSILFLVEANPGPGLGILLAYMFFGKGSSKSTAPGAAIIHFFGGIHEIYFPYILMKPALILAAIAGGASGLLTFTIFNAGLVAAASPGSIIALMAMTPRGGYFGVLAGVLVAAAVSFIVSAVILKSSKASEEDLAAATEKMQSMKGKKSQAAAALEAEQAKAEEASELSPESVNKIIFACDAGMGSSAMGASILRNKVKKAELDISVTNTAINNLPSDADIVITHKDLTDRAKAKLPNATHISVDNFLNSPKYDELIEKLKK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific EIICB component, EIICB-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RDRP_PVSP
Sequence: MYGPFLLKEFLNDVPLKPMHNTRMMAEAKFDFEEKKTQKSAATIENHSNRSCRDWLADMGMVFSKSQLCTKFDNRFRDAKAAQTIVCFQHSVLCRFAPYMRYIEKKLNEVLPATFYIHSGKGLEELNKWVIESKFEGVCTESDYEAFDASQDQYIVAFELALMRYLGLPNDLIEDYKYIKTHLGSKLGNFAIMRFSGEASTFLFNTMANMLFTFLRYKLKGDERICFAGDDMCANRALFIKDTHEGFLKKLKLKAKVDRTNRPSFCGWSLSSDGIYKKPQLVFERLCIAKETANLANCIDNYAIEVSYAYKLGERIKERMSEEELEAFYNCVRVIIKHKHLLKSEIRSVYEEV
What is the function of this protein?
RNA replication.  The central part of this protein possibly functions as an ATP-binding helicase.
What are the official names of this protein?
RNA replication protein, 152 kDa protein, ORF1 protein.
What is the protein family that this protein belongs to?
Belongs to the potexviruses/carlaviruses RNA replication protein family.
Protein: MET15_BOVIN
Sequence: MLRYPYFCRIHKNFLSCWLESGIYNLGVWPKKIHATAERYNEYEAQEETDQTGIQELHRSQDRDSGVMTKLHIPVMVDEVVRCLAPQKGQVFLDMTFGSGGHTRAILQKEPDITLYALDRDPTAYAIAEQLSELYPKQIRAILGQFSQAEALLMKAGVQPGTLDGVLLDLGCSSMQLDTPERGFSLRKDGPLDMRMDGDRYPDMPTAADVVNALDQQALASILRAYGEEKHAKKIASAIIQARGLYPITRTQQLASIVAGAFPPSALYARKDLLQRPTHIATKTFQAFRIFVNNELNELYTGLKTAQKFLRPGGHLVALSFHSLEDRIIKRFLLGISMTERFNLSARQKVIQKSQLDSDQENKEGVSTGKAPLMWKLIHKKVLTPEDEDVQDNPRGRSAKLRAAIKL
What is the function of this protein?
N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA.  Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits.
What are the official names of this protein?
12S rRNA N4-methylcytidine methyltransferase, 12S rRNA m4C methyltransferase, Methyltransferase 5 domain-containing protein 1, Methyltransferase-like protein 15.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYR_COXBN
Sequence: MIDLSTMKQQIETLLNQAIERLKTKGVLKPEVTPVIKITHTTDPQHGDFATNLALTLSKAAGMRPHALAEKIVEALPPSGQITEVEIAGPGFINFFVTEGSYQTVVSSILKAGKDYGRSEMGKGQRVHMEYVSANPTGPLHVGHGRGAAYGACVANLLNAAGFEVHREYYVNDAGRQMGILALSVWVRYLQGYEASIELPKNAYQGEYIIDIAEALKAKYGKQFYHSVESIQAKIPEEIDSNADPEAYLDAWVTAQKDLLGPKDFECVFQAALDSILNDIKNDLEEFGVTYDDWFPESRLVREGLIQEGLDLLTKHGYVYEKNGAQWFRATALGDEKDRVLIRKNGLPTYFAADVAYHLHKFNQGYDQIIDIFGADHHGYIPRIRGFLKGLGKAPEKLHILLVQFAILYRGNEKVSMSTRGGTFVTLRELRHEVGNDAARFFYIMRKPDQHLDFDLELAKSQSNENPVYYIQYAHARICSVFRQLKTTQKNWDRPRGMENLSLLSTNYEKELLATLGRYPEVIKRAAMNYAPHLLAHYLQTLANQFHTYYNAERFLIEDDNLRNARLNLINAVQQIIRNGLTLLGVSAPEEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COABC_MYCS2
Sequence: MSARKRIVVGVAGGIAAYKACTVVRQLTEAGHSVRVVPTESALRFVGAATFEALSGNPVHTGVFTDVHEVQHVRIGQQADLVVIAPATADLLARAVAGRADDLLTATLLTARCPVLFAPAMHTEMWLHPATVDNVATLRRRGAVVLEPASGRLTGADSGPGRLPEAEEITTLAQLLLERADALPYDMAGVKALVTAGGTREPLDPVRFIGNRSSGKQGYAVARVLAQRGADVTLIAGNTAGLIDPAGVEMVHIGSATQLRDAVSKHAPDANVLVMAAAVADFRPAHVAAAKIKKGASEPSSIDLVRNDDVLAGAVRARADGQLPNMRAIVGFAAETGDANGDVLFHARAKLERKGCDLLVVNAVGENRAFEVDHNDGWLLSADGTESALEHGSKTLMATRIVDSIAAFLKSQDG
What is the function of this protein?
Catalyzes two sequential steps in the biosynthesis of coenzyme A.  In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.  In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
What are the official names of this protein?
Coenzyme A biosynthesis bifunctional protein CoaBC, DNA/pantothenate metabolism flavoprotein, Phosphopantothenoylcysteine synthetase/decarboxylase, PPCS-PPCDC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PPC synthetase family.
Protein: VEMP_CVPPU
Sequence: MTFPRALTVIDDNGMVINIIFWFLLIIILILLSIALLNIIKLCMVCCNLGRTVIIVPAQHAYDAYKNFMRIKAYNPDGALLA
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: GSA_CHLPB
Sequence: MPQLTRSAELFEKAKQFIPGGVNSPVRAFKSVGGTPIFMAKGQGAYMTDVDGNTYLDYVGSWGPFILGSMHPRITAAIENTLTKIGTSFGTPIEMEIEIAELLTQIVPSIEMVRMVNSGTEATMSAVRLARGYTGRDKIIKFEGCYHGHGDSFLIKAGSGALTLGAPDSPGVTKGTANDTLNAKYNDIESVRVLVKENKDSIAAIIIEPVAGNTGVIPAKTDFLQALRDLCTEEGIVLIFDEVMCGFRVALGGAQERYGITPDLTTMGKIIGGGLPVGAFGGKREIMQRVAPIGDVYQAGTLSGNPLALTAGLETLKILRDDNPYPELERKAAFLEEGFRDNMNKLGLSYVQNRVGSMACLFFTETPVENYDTAITCDLKKYGKYYHSMLDQGIYLAPSQFEAMFTSAVMTDEDLEKTVKANYVALQAAEA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDC1_HUMAN
Sequence: MEVAANCSLRVKRPLLDPRFEGYKLSLEPLPCYQLELDAAVAEVKLRDDQYTLEHMHAFGMYNYLHCDSWYQDSVYYIDTLGRIMNLTVMLDTALGKPREVFRLPTDLTACDNRLCASIHFSSSTWVTLSDGTGRLYVIGTGERGNSASEKWEIMFNEELGDPFIIIHSISLLNAEEHSIATLLLRIEKEELDMKGSGFYVSLEWVTISKKNQDNKKYEIIKRDILRGKSVPHYAAIEPDGNGLMIVSYKSLTFVQAGQDLEENMDEDISEKIKEPLYYWQQTEDDLTVTIRLPEDSTKEDIQIQFLPDHINIVLKDHQFLEGKLYSSIDHESSTWIIKESNSLEISLIKKNEGLTWPELVIGDKQGELIRDSAQCAAIAERLMHLTSEELNPNPDKEKPPCNAQELEECDIFFEESSSLCRFDGNTLKTTHVVNLGSNQYLFSVIVDPKEMPCFCLRHDVDALLWQPHSSKQDDMWEHIATFNALGYVQASKRDKKFFACAPNYSYAALCECLRRVFIYRQPAPMSTVLYNRKEGRQVGQVAKQQVASLETNDPILGFQATNERLFVLTTKNLFLIKVNTEN
What are the official names of this protein?
NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus.
Protein: WOR1_GIBF5
Sequence: MAGTMPLRPTYVGFVRDTTDALLIFEACLSGTLSHVPRRPHDRERQDLIKSGNIFVYEEHASGIKRWTDSISWSPSRILGNYLLYRELEKPFPPGEKKRARGRNGKSTTQSGGISKARQRNTVPFPQGLEHGNEYPSVPSDDERHLVGSLVDSYDFKEQGLVKKTISITYQGVPHHLVSYYNVEDVKAGLLSGPSDDPRLRGVVPRTELMNGQNFRAPVEEAMGGSYMPSMVASIGYPTLQHQSQMHQSQMHQPQMHQPQMHQSQMHQSQMHQPQMHQPQAHQPQVHQPQVHPPQVHQPQAHQPQYQSQTLHPTHGYQQTYAGQPNAPSSTWW
What is the function of this protein?
Global transcriptional regulator that acts as an activator of secondary metabolism.  Required for expression of a yet uncharacterized secondary metabolism gene cluster containing a non-canonical non-ribosomal peptide synthetase.  Not required for conidiogenesis nor for pathogenicity, but is involved in vegetative growth.
What are the official names of this protein?
Global transcription regulator sge1.
What is the protein family that this protein belongs to?
Belongs to the MIT1/WOR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR7_EUOAL
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQILYRAMKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GUAC_ACISJ
Sequence: MEIFDYDNILLLPRKCRVESRSECDTSVELGERRFRLPVVPANMKTVVDEKICTWLAQNGYFYVMHRFDLDNVQFVKDMHAQGCFASISLGVKQPDYDTVDRFVAEGICPEYITIDIAHGHADSVKNMITYLKAKIPAAFVIAGNVGTPEAVIDLENWGADATKVGIGPGKVCITKLKTGFGTGGWQLSALKWCARVATKPIIADGGIRSHGDIAKSVRFGATMVMVGSLFAGHEESPGKTVEVDGELYKEYYGSASDFNKGEYKHVEGKRILEPIKGKLADTLTEMEQDIQSSISYSGGKKLMDIRKVNYVILGGDNAGEHLLM
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: RPB6_ASFM2
Sequence: MADNDNEDVIMDDLVEEYVETEEENFVDSEEESEDKSEDKDEIVESPSICEGFVQASSQTLVIIPDNERITSNVLTTFEATRLVAVRAQQLAINGSTMLKKKYSSPIDIAKQELFNRKIPLLVMRCIKVTPEGQKIVEIWNPREMGIPLLD
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB6 homolog, RPB6 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: YJ2D_SCHPO
Sequence: MEGENDPLLGSYKPKRRRSSLVYGLSRPQFLDTAASEVSPIPQERPTTSLRKPTPRVQRPATDVSYGALEETEENESIASGLSVQEDFNSKAWWKELTLLIKFATPVVLTSLLQYGEVVTTVFSLGHLGKTELAAASLSNMTATITAFAIYQGIVSALDTVGTQSFGSGNYEMVGLHLQRILAILLLIQFPIFLIWWKIEGILLFLRQDPLTCMFAAKYMRVMMLASPAYALFEALKRFLQVQGIFHPVTYILAIVVPINIFLNYLFVWSPWVGFGFLGAPVAVALTLWSACAVLIIYIMKVNGRQAWGGFSREALKNWGPLCRLAVPGVIMICSEYWAFELVTFASGVLGTTELASMSVLSTTSTLSYNLAFGVAAAAATRVGNLIGAGNTKLAKLATHVSINLGAAIGVIIAVILFLTRNTWTYIFTSDKDVVALVATIIPLVALINIADNTQCVAGGLLRGQGRQRIGGVVNFIAYYLLGLPVAIILCFKLDWGLYGLWIGIGAAILIIAGVETWCSLHVNWDHLVELANRQFDEA
What are the official names of this protein?
Uncharacterized transporter C4B3.13.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: ELHL_APLCA
Sequence: MKANTMFIILCLTLSTLCVSSQFTSVLGKIFVTNRAVKSSSYEKYPFDLSKEDGAQPYFMTPRLRFYPIGKRAAGGMEQSEGQNPETKSHSWRERSVLTPSLLSLGESLESGISKRISINQD
What is the function of this protein?
The atrial gland peptide A and peptide B precursors are the source of the 2 peptides that, upon release from this reproductive system gland, initiate the egg-laying process by exciting the bag cell neurons.  These neurons, clustered in neural connectives near the abdominal ganglion, in turn release other peptides that act directly on the ganglion and also, via the circulating hemolymph, on many other organs to control the physiological processes of egg-laying.  One of these other peptides is the egg-laying hormone.
What are the official names of this protein?
Atrial gland peptide B, ELH-1L.
What is the protein family that this protein belongs to?
Belongs to the molluscan ELH family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIE_ECOHS
Sequence: MYQPDFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYPTVAIGGVSLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: TRPM6_HUMAN
Sequence: MKEQPVLERLQSQKSWIKGVFDKRECSTIIPSSKNPHRCTPVCQVCQNLIRCYCGRLIGDHAGIDYSWTISAAKGKESEQWSVEKHTTKSPTDTFGTINFQDGEHTHHAKYIRTSYDTKLDHLLHLMLKEWKMELPKLVISVHGGIQNFTMPSKFKEIFSQGLVKAAETTGAWIITEGINTGVSKHVGDALKSHSSHSLRKIWTVGIPPWGVIENQRDLIGKDVVCLYQTLDNPLSKLTTLNSMHSHFILSDDGTVGKYGNEMKLRRNLEKYLSLQKIHCRSRQGVPVVGLVVEGGPNVILSVWETVKDKDPVVVCEGTGRAADLLAFTHKHLADEGMLRPQVKEEIICMIQNTFNFSLKQSKHLFQILMECMVHRDCITIFDADSEEQQDLDLAILTALLKGTNLSASEQLNLAMAWDRVDIAKKHILIYEQHWKPDALEQAMSDALVMDRVDFVKLLIEYGVNLHRFLTIPRLEELYNTKQGPTNTLLHHLVQDVKQHTLLSGYRITLIDIGLVVEYLIGRAYRSNYTRKHFRALYNNLYRKYKHQRHSSGNRNESAESTLHSQFIRTAQPYKFKEKSIVLHKSRKKSKEQNVSDDPESTGFLYPYNDLLVWAVLMKRQKMAMFFWQHGEEATVKAVIACILYRAMAHEAKESHMVDDASEELKNYSKQFGQLALDLLEKAFKQNERMAMTLLTYELRNWSNSTCLKLAVSGGLRPFVSHTCTQMLLTDMWMGRLKMRKNSWLKIIISIILPPTILTLEFKSKAEMSHVPQSQDFQFMWYYSDQNASSSKESASVKEYDLERGHDEKLDENQHFGLESGHQHLPWTRKVYEFYSAPIVKFWFYTMAYLAFLMLFTYTVLVEMQPQPSVQEWLVSIYIFTNAIEVVREICISEPGKFTQKVKVWISEYWNLTETVAIGLFSAGFVLRWGDPPFHTAGRLIYCIDIIFWFSRLLDFFAVNQHAGPYVTMIAKMTANMFYIVIIMAIVLLSFGVARKAILSPKEPPSWSLARDIVFEPYWMIYGEVYAGEIDVCSSQPSCPPGSFLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLDMESISNNLWKYNRYRYIMTYHEKPWLPPPLILLSHVGLLLRRLCCHRAPHDQEEGDVGLKLYLSKEDLKKLHDFEEQCVEKYFHEKMEDVNCSCEERIRVTSERVTEMYFQLKEMNEKVSFIKDSLLSLDSQVGHLQDLSALTVDTLKVLSAVDTLQEDEALLAKRKHSTCKKLPHSWSNVICAEVLGSMEIAGEKKYQYYSMPSSLLRSLAGGRHPPRVQRGALLEITNSKREATNVRNDQERQETQSSIVVSGVSPNRQAHSKYGQFLLVPSNLKRVPFSAETVLPLSRPSVPDVLATEQDIQTEVLVHLTGQTPVVSDWASVDEPKEKHEPIAHLLDGQDKAEQVLPTLSCTPEPMTMSSPLSQAKIMQTGGGYVNWAFSEGDETGVFSIKKKWQTCLPSTCDSDSSRSEQHQKQAQDSSLSDNSTRSAQSSECSEVGPWLQPNTSFWINPLRRYRPFARSHSFRFHKEEKLMKICKIKNLSGSSEIGQGAWVKAKMLTKDRRLSKKKKNTQGLQVPIITVNACSQSDQLNPEPGENSISEEEYSKNWFTVSKFSHTGVEPYIHQKMKTKEIGQCAIQISDYLKQSQEDLSKNSLWNSRSTNLNRNSLLKSSIGVDKISASLKSPQEPHHHYSAIERNNLMRLSQTIPFTPVQLFAGEEITVYRLEESSPLNLDKSMSSWSQRGRAAMIQVLSREEMDGGLRKAMRVVSTWSEDDILKPGQVFIVKSFLPEVVRTWHKIFQESTVLHLCLREIQQQRAAQKLIYTFNQVKPQTIPYTPRFLEVFLIYCHSANQWLTIEKYMTGEFRKYNNNNGDEITPTNTLEELMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEVKQSRGMVFGPANLGEDAIRNFIAKHHCNSCCRKLKLPDLKRNDYSPERINSTFGLEIKIESAEEPPARETGRNSPEDDMQL
What is the function of this protein?
Essential ion channel and serine/threonine-protein kinase.  Crucial for magnesium homeostasis.  Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney.  Isoforms of the type M6-kinase lack the ion channel region.
What are the official names of this protein?
Transient receptor potential cation channel subfamily M member 6, Channel kinase 2, Melastatin-related TRP cation channel 6.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM6 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VKT18_DRYCN
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPHFCHLPADPGRCNALSEAFYYNPVQRKCLKFRYGGCKANANTFKTIDECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor 18, SPI-18.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: MDH_RICPR
Sequence: MKKNPKISLIGSGNIGGTLAHLISLKKLGDIVLFDVSEGLPQGKALDLMQAATIEGSDIKIKGTNDYRDIEGSDAVIITAGLPRKPGMSRDDLISVNTKIMKDVAQNIKKYAQNAFVIVITNPLDIMVYVMLKESGLPHNKVIGMAGVLDSSRFNLFLAKEFKVSVKNVNSIVLGGHGDTMVPLLRYSTISGVPIPDLIKMGLSSNKNIEKIIDRTKNGGGEIVKLLKTGSAYYAPAASAIAMLESYLKDKRQILTCAAYLQGEYDIHDLYIGVPIIIGKEGVIKVIELQLTEEEKILFYKSVTEVKKLIDTIQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: HSPR2_ARATH
Sequence: MVDMDWKRKMVSSDLPNSPKLSSKLHVTIPSPFKIVPVSSPISCSAPALCSAYELYLRLPELRKLWSSRDFPQWTSEPILKPALQALEISFRLVFAVCSDTRPYINHREWNRRLDSLITKQIQLVAAICEDEEEEGISAEAPVGGGRSSLSLLPQLATWRRSEALGKKILYTIDNEMSRCKYTLGLGEQNIAGKPNLRYDAICRPNEIYSLKDNPYADHIDNHENQTLYIIHQILESWIYASGNLLNRIVSSIEEEKFGKASNDVYLLEKIWKILAEIEDLHMLMDPEDFLKLKKQLQIKSTGKNDAFCFRSKGLVEMMKMSKDLRQKVPAVLAVEVDPTGGPRLQEAAMKLYARKTECDKIHLLQGMQAVEAAAKSFFFGYRQLVAAMMGSAEMNATASQESCDSLSQIFMEPTYFPSLDAAKTFLGEFWSHLG
What is the function of this protein?
Positive regulator of basal resistance.
What are the official names of this protein?
Nematode resistance protein-like HSPRO2, AKINbetagamma-interacting protein 2, Ortholog of sugar beet HS1 PRO-1 protein 2, Protein Hs1pro-2.
Protein: PSBT_ORYSA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKVK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SURE_ACTSZ
Sequence: MNILLSNDDGYHAEGIQTLATYLRKFANVVIVAPDRNRSAASSSLTLVEPLRPRQLDNRDYCINGTPADCVHLALNGFLSGRVDLVVSGINAGVNLGDDTLYSGTLAAALEGRHLGLPAIAVSLDGRQHYESAAKIVCDLIPKLHGQLLKSREILNINVPDLPYENLKGLKVCRLGHRSSAAEVIKQADPRGEAIYWIGPAGLPEDEAEGTDFHAVQQGYVSITPIQPDLTAHHSLRSLQTWLEQE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_RUEPO
Sequence: MTAQLHMMSDKHDQDNDASVLLQTRPRTKRPPLYKVLLLNDDYTPMEFVVHVLERFFGMNHAQAFEIMLTVHKKGVAVVGVFSHEIAETKVSLVMDFARRHQHPLQCTMEKED
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.