PharMolix/UniProtQA huggingface dataset:
Protein: RAB19_MOUSE
Sequence: MQFSSSSRTSDENVDYLFKVILIGDSNVGKTCVVQHFKSGVYSESQQNTIGVDFTVRSLEIDGKKVKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESVPHWIHEIEKYGAANLVIMLIGNKSDLWEKRHVLFEDACTLAEKHGLLAVLETSAKESRNIDEVFVLMAKELIARNSLHLYGESAQQGLSQDSSPVLVAQVPNESTRCTC
What are the official names of this protein?
Ras-related protein Rab-19.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: UBIG_YERPA
Sequence: MRAKTTSRHHNVDEQEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRSGGIFEKKVLDVGCGGGILAESMAREGAQVTGLDMGYEPLQVARLHALETGVKLEYVQETVENHAQQHPQHYDVVTCMEMLEHVPDPASVVRACAQLVKPGGHVFFSTINRNTKSWLMAVVGAEYLLKMVPKGTHDAKKFIRPSELIGWVDQTPLLERHIIGLHYNPITDHFKLGRNVDVNYMVHTQRDSE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: Y2175_AQUAE
Sequence: MKKMKKLLLLLSASFAFSLQMDFKEVKKFPYIKYVTAWKGTPAETKDVAVPNVYIVVGQKESPEVLTSAAKVAFYLGQWTDGIGLSPKLVKEGKIPKLIISDKEVEKYKDRNLIVIGTNNEIVRELGLKFKEPTLKVVEKDGRKILIVGGKDTKEVVKAASFLADRVISFKVGAYNTFFNWVRVRGMIEHGNYEGAYDMLTDSRGVHACGRNMSLAAPMMAKFPPEVKKVVKKRNKIMYVELPKALKEENKEKAKKLWREAMITCFQCHHGIGIPKMRKFEPLADIHSKHQRIANKYGLSCKDCHYGITEYRGYEEGTTEQ
What are the official names of this protein?
Uncharacterized protein aq_2175.
Protein: BHSA_ECOLI
Sequence: MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAGTNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGTAVIYK
What is the function of this protein?
Reduces the permeability of the outer membrane to copper.  Seems to be involved in the regulation of biofilm formation.  May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction.
What are the official names of this protein?
Multiple stress resistance protein BhsA, Copper-induced outer membrane component.
What is the protein family that this protein belongs to?
Belongs to the BhsA/McbA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: MP1_CARMV
Sequence: MDIESEVPVVGKQMLAGNRGKQKTRRSVAKDAIRKPASDSTNGGNWVNVADKIEVHIHFNF
What is the function of this protein?
Cell-to-cell movement.  Displays RNA-binding activity.
What are the official names of this protein?
Double gene block protein 1, DGBp1, Movement protein P7.
What is the protein family that this protein belongs to?
Belongs to the carmovirus double gene block protein 1 family.
Protein: Y1467_DESAP
Sequence: MAVEYHLTIKEMAAELRPRERLAAHGVQSLSDAELLAILLRSGTVTTTAIDLANQILSRFGGLRGLAEAGIEELQAVKGVGPAKSAEVRAAFELGRRAACRPGEWQPTVRTPEEAAGLVMEEMRYFDREHFWALVLNTKNRVLAVEKVSVGTLNSSSVHPRELFKNAIRRSAAALILVHNHPSGDPAPSPQDIELTQRLFEAGEIVGIKVLDHIIIGDNKFTSLKLEGLF
What are the official names of this protein?
UPF0758 protein Daud_1467.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: PQQD_ACIAD
Sequence: MASKRIIRMSDLLHTTPVFNRGYRFQWEQAQQSYVILYPEGLVRLNESATLILKQIDGKLTVHDIIQNLSAQFPDATGLDQDIVEFLKQAESRQWICLQ
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.
Protein: CDN1B_HUMAN
Sequence: MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
What is the function of this protein?
Important regulator of cell cycle progression.  Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA (PubMed:28666995).  Involved in G1 arrest.  Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes.  Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation.  Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1.
What is the protein family that this protein belongs to?
Belongs to the CDI family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endosome. Note=Nuclear and cytoplasmic in quiescent cells. AKT- or RSK-mediated phosphorylation on Thr-198, binds 14-3-3, translocates to the cytoplasm and promotes cell cycle progression. Mitogen-activated UHMK1 phosphorylation on Ser-10 also results in translocation to the cytoplasm and cell cycle progression. Phosphorylation on Ser-10 facilitates nuclear export. Translocates to the nucleus on phosphorylation of Tyr-88 and Tyr-89. Colocalizes at the endosome with SNX6; this leads to lysosomal degradation (By similarity).
Protein: SYP_ECOBW
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPQVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVAGDPSPDGQGRLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STCD_RHIME
Sequence: MPNDPLLQPYQLKHLTLRNRIIVTAHEPAYPEDGMPKERYRAYTVERARGGVAMTMTAGSAAVSKDSPPVFNNLLAYRDEIVPWIREMTDAVHEEGAVIMIQLTHLGRRTRWDKGDWLPVVAPSHHREAAHRAFPKKIEDWDIDRIIKDFADAAERMKAGGMDGVELEAYGHLIDQFASPLTNELDGPYGGSLDNRMRFCFDVLKAIRARVGDEFILGVRYTADECLPGGTDKAEGLEISKRLKESGLIDYLNIIRGHIDTDPGLTDVIPIQGMANSPHLDFAGEIRAATNFPTFHAAKIPDVATARHAIASGKVDMVGMTRAHMTDPHIVRKIIEKREEDIRPCVGANYCLDRIYQGGAAYCIHNAATGRELTMPHSIAKAHCRRKVVVVGTGPAGLEAARVAGERGHEVIVFEAASDPGGQVRLTAQSPRRREMISIIDWRMSQCEKLGVTFHFNTWAEAEAIQAESPDVVIIATGGLPHTEVLSRGNELVVSAWDIISGDAKPGTNVLIFDDAGDHAALQAAEFLATAGARVEIMTPDRSFAPEVMAMNLVPYMRCLQKLDVTFTVTYRLEAVEKSGNELVAHVGSDYGGISKQRTFDQVVVNHGTIPLDELYFELKPFSSNLGEIAHDQMIAGEPQSVVRNAEGKFQLFRIGDAVAARNTHAAIYDALRLLKDI
What is the function of this protein?
Possible NADH-dependent oxidase, functions as a demethylase that converts N-methylproline to proline.
What are the official names of this protein?
Probable N-methylproline demethylase, Stachydrine utilization protein StcD.
Protein: COSA_PICSI
Sequence: MTLNVDEEVERLKEEIKRLAQPRPDGSYVVKFGVLFSDDRCANIFEALVGTLRAAKKRKVVTYDGELLLQGVHDNVEIVLLKPPTQATQAEGVGA
What are the official names of this protein?
Costars family protein WS02710_H03.
What is the protein family that this protein belongs to?
Belongs to the costars family.
Protein: RL4_LACPL
Sequence: MTSVALFKQDGTQNGDVTLNDAVFGVEPNENVVFDAILMQRASMRQGTHAVKNRSARRGGGRKPWRQKGTGRARQGSIRSPQWRKGGIVFGPTPRSYSYKLPKKVMRLALKSVLSQKVLDNSLVAVDSLAFDAPKTKDFVNVLNNLNVDTKTLVLVEEDNEKAALAGRNLPNVKILKAKGVNVLDVANSDKLVVTQKALDQLEEALA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS11_FRACC
Sequence: MPPKTRAAGAKKVRRKEKKNVAHGHAHIKSTFNNTIVSITDPSGNVISWASAGHVGFKGSRKSTPFAAQMAAENAARKAQEHGMRKVDVFVKGPGSGRETAIRSLQAAGLEVGAIQDVTPTPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FER1_RAPSA
Sequence: SAVYKVKLIGPDGQENEFDVPDDQYILDAAEEAGVDLPYSCRAGACSTCAGKIEKGQVDQSDGSFLEDHHFEKGYVLTCVAYPQSDLVIHTHKEEELF
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin, root R-B1.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS5_ACIAC
Sequence: MAKFQPKVQTEGQDDGMREKMIAVNRVTKVVKGGRILGFAALTVVGDGDGRVGMGKGKSKEVPAAVQKAMEECRRNLVKVSLKNGSIHHSVKGHHGAASVELHPAPKGTGIIAGGPMRAVFEVVGITDIVAKSHGSSNPYNMVRATFDALVNSTTPAEVAAKRGKSVEDIFA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y049_BUCAP
Sequence: MQDALFFISNNLVLSLIWLFFLILIFFLSTKNMFLKSKIINNFHAINLINQKKAIIVDTRSVELYDSGHIINAINIPFNNICRKTIKKLSLSRSVPIILIIDSLEYNKYIKKFTKYGLDKVYFLKNGMNSWNSENLPTTFKKNIFLK
What are the official names of this protein?
Uncharacterized protein BUsg_049.
Protein: NU3M_PERPL
Sequence: MNMLTALLVNITLSMLLIIIAFWLPQLNLYTEKANPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQMYYINIMMSTAFILVSVLALGLAYEWLQKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ANR63_MOUSE
Sequence: MLKPKDLCPRAGTRTFLEAMQAGKVHLARFVLDALDRSIIDCRAEQGRTPLMVAVGLPDPAMRSRFVRLLLEQGAAVNLRDERGRTALSLACERGHLDAVQLLVQFSGDPEATDSAGNSPVMWAAACGHGAVLEFLVRSFRRLGLRLDRTNRAGLTALQLAASRGHGTCVQALTGPWGRAAAAAAARGSNSDSPPGHPAPAPSPERRRPSPRRLPRPLLARFARAAGGHGHGHGHGHGHGGELASAGKGSVRYRAQGNERPELGRSMSLALGTMTEEETARLRAGALMARPNSPQSSGSGRWRSQEVLEGAPLALMQAPVGLSPHPEGCPGSGRLGLRRRSTAPDIPSLVGEASGPESGPELENNALPFSVPGPKPWQAGTEAVVLQAQR
What are the official names of this protein?
Ankyrin repeat domain-containing protein 63.
Protein: LG3BP_BOVIN
Sequence: MAPLRLFWIWLLVVGTRGVKDGDMRLADGGSANQGRVEIYYNGQWGTVCENMWDLTDASVVCRALGFQNATEALGGAAFGPGYGPIMLDEVRCTGTEPSLANCSSLGWMRSNCRHDKDASVICTNETRGVYTLDLSGELPAALEQIFESQKGCDLFITVKVREEDEIAMCAHKLILSTNPEAHGLWKEPGSRVTMEVDAECVPVVKDFIRYLYSRRIDVSLSSVKCLHKLASAYQAKQLQSYCGHLFAILIPQDPSFWTPLELYAYALATRDPVLEEICVQFLAWNFGALTQAEAWPSVPPALLQGLLSRTELVVPSELVLLLAVDKWSQERRTSHKEVEALVGQVRFPMMPPQDLFSLQFNLSLYWSHEALFQKKILQALEFHTVPFELLAQYWGLNLTEGTYQPRLYTSPTWSQSVMSSSYNPSRSFQTPQHPSFLFHDSSVSWSFVYLPTLQSCWNYGFSCSSDDPPLLALSKSSYSKSNPTIGYENRALLHCEGSFVVDVIDFKGWKALVPSALATNSSRSTSLFPCPSGVFSRFQVVIRPFYLTNSTDMD
What is the function of this protein?
Promotes integrin-mediated cell adhesion.  May stimulate host defense against viruses and tumor cells (By similarity).
What are the official names of this protein?
Galectin-3-binding protein, Lectin galactoside-binding soluble 3-binding protein.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix.
Protein: HEM1_ACIBT
Sequence: MSFFALGVNHQTASVELREQIAFNAERLSNLLAEQRHHESLKDLVVVSTCNRTEVYAMAEDAESLLKWLADANNIDVKQLIHHVYRYENAQAITHLMRVASGLDSLMLGEPQILGQVKSALALSKEAQTVSPELNSVFEYAFYAAKRVRSETAVGSHAVSMGYAVAQLALQVFSKPEKLTVMVVAAGEMNSLVAKHLAEMGVAKMIICNRSRERADQLAQEIAHQVEVEIIDFSDLAENLYRADVVSSCTGSLHQVIAYADVKTALKKRRYQQMLMVDLAVPRDIDPKVESLDGVYLYGVDDLQSVIDENLAQRRQAAVEAEVMVNQLATQLITHQKVKEAGSTIHAYRQHSEEISQRELTHALEALHHGGNPEQVLQQFAHRLTQKLIHPTSMLLREAAKAESPDYFEWLQQHLQDVFDHERKPKR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RNH_SHEB5
Sequence: MTELKLIHIFTDGSCLGNPGPGGYGIVMNYKGHTKEMSDGFALTTNNRMELLAPIIALESLKEPCQVVLTSDSQYMRQGIMTWIHGWKKKGWMTSNRTPVKNVDLWKRLDKASQMHTIDWQWVKGHAGHAENERCDVLARTAAESKPTQPDLGYQP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPB_BURP1
Sequence: MQHHACSPPRLILASSSRYRRELLERLRVPFDVVAPEIDETPLPDETPCATALRLAAAKARAAAERARAPHGALVIGSDQVATFDGLQIGKPGTHARALAQLQAMRGRDVEFHSALCLYDSRSGATQSEDIVTRVRFRTLTDVELDAYLRAETPYDVAGSAKSEGLGIALLDAIDSDDPTALVGLPLIALTRMLRAAGYPLFGAPAPAADGVNGR
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_VIBVU
Sequence: MTIRILPARLANQIAAGEVVERPASVVKELVENSLDSGATKIDIDIEKGGAKLIRIRDNGSGIVKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRPATQEQAWSAYTEGRDMQVKLQPTAHPIGTTVEVVDLFFNTPARRKFLRTEKTEFAHIDELLKRIALSCFDVSITLRHNGKVIRQYRAAHNDLQAEKRLATVCGQAFVRCMLKIELEHQGLKLHGWITTPEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLKPEQFAAYVLFIELDPHQVDVNVHPAKHEVRFHQARLVHDFIYQALASALAQSDSIEQPQINESAFHYQAEPEVAPQGSFPAESNEVPQAVYHAIEKAPAYPRKAGQEQQLQPVAPLESSFSSEQGREVSPAPHNERKAWMESRSPARHTTSSNQSERYGEPAPSKQQVKAYAELLHTPDFPSQNVECHPSPSIASPVQELGKAVSVVAQRYLLTTTKAGCQLISLARAEFYRTLGQLNGDKAPLKSQPLLVPLSLKLEKGLVHAAQEHQDRFARMGILFKMRNEKALMVMGVPAPLRQQNLQLLIPDLLSYAASQAQKEELAQNDTAMAQWLALRVAKVKSHYTLSEAIQIISELEQLWQEKLPLQDSQLVTSVDFSATIAQLT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PDXH_SALPK
Sequence: MSDNDQLQQIAHLRREYTKGGLRRRDLPAEPLTLFERWLGQACDARLADPTAMVVATVDDKGQPYQRIVLLKHYDEKGLVFYTNLGSRKAHQIEHNPRISLLFPWHMLERQVMVTGKAERLSTLEVVRYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSIEQMEFWQGGEHRLHDRFLYQRDDGAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RS3_DESAH
Sequence: MGQKVNPIGLRLNIVKTWDSRWYADKNYADFVFEDYKLRAFLKKKLFHAGISKIEIERFTKRIRIRVFAARPGIIIGKKGSEIALLKKEIEQMITPEVLIDIQEIRRPEIDAQLVAENISAQLERRIAFRRAMKRSVSSAMRFGAQGIKIICSGRLGGAEMARTEWYKEGRIPLHTLRADVDYGFTEAKTTYGAIGIKTFIFKGEVLKADRNVKA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ATPE_FRATF
Sequence: MTKKYLKVDVVSPLGSVFKGEADMVSLRGSAGEMGIVYGHTELLSTLPAGVVNVRKGQHTDVLYVSGGIVEVTPTRVTIMVDDMERAENLNQAEAEKARARAKEVLKNPDASKLDIEAANKRLKEADARLKALNSSNGLYYSKDD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: END8A_MYCTU
Sequence: MPEGHTLHRLARLHQRRFAGAPVSVSSPQGRFADSASALNGRVLRRASAWGKHLFHHYVGGPVVHVHLGLYGTFTEWARPTDGWLPEPAGQVRMRMVGAEFGTDLRGPTVCESIDDGEVADVVARLGPDPLRSDANPSSAWSRITKSRRPIGALLMDQTVIAGVGNVYRNELLFRHRIDPQRPGRGIGEPEFDAAWNDLVSLMKVGLRRGKIIVVRPEHDHGLPSYLPDRPRTYVYRRAGEPCRVCGGVIRTALLEGRNVFWCPVCQT
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  DNA glycosylase that recognizes and removes damaged pyrimidines.  Excises Tg:A (thymine glycol, prefers 5R isomers), Tg:G, 5,6-dihydrouracil:G base pairs and urea:A, also excises oxidized purine derivatives guanidinohydantoin:C and spiroiminodihydantoin:C.  Poorly cleaves dsDNA with uracil substitutions, thus also acting as a weak uracil-DNA glycosylase.  Acts on DNA bubble and 3'-fork structures, suggesting a role in replication-associated DNA repair.  Activity on 7,8-dihydro-8-oxoguanine (8-oxoG) is debated; a report shows weak activity (PubMed:18457574), whereas another shows none (PubMed:20031487).  Has AP (apurinic/apyrimidinic) activity and introduces nicks in dsDNA strand, inefficiently cleaves ssDNA with AP sites and uracil.  Probably cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.  Cleaves ssDNA containing an AP site.  Complements an E. coli fpg mutY but not nei nth double mutant (PubMed:18457574).
What are the official names of this protein?
Endonuclease 8 1, DNA glycosylase/AP lyase Nei 1, DNA-(apurinic or apyrimidinic site) lyase Nei 1, Endonuclease VIII 1.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: UPPP_LAWIP
Sequence: MMSWLTIGVILGLVQGITEFLPVSSTGHLIIVAKFLHFTGSKASVFEVAVQLGSIMAVVVIYWNRFIGLIRPEKNKKFTGLYGIWLLFLTTLPPGIIGFLFHSYIKTLFTIPSVIAALTTGSIFMLISEQLCRNISQRIVTLDELTPKTALGIGFFECLALWPGFSRSAATIMGGMLLGAKRHLAAEYSFIAAVPVMFAATGYDLLKNWDLFTANDLPLFITGMICAFLAAWITIKVFILLISKISLRPFAYYRLLLAFIVYLCIK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VF364_ASFWA
Sequence: MYFLVADHREHHVIPFLKTDFHHMHQNPIQKNQALLEIKQLFTGDYLICKSPSTILACIERKTYKDFAASLKDGRYKNRQKMLSLREQTNCQLYFFVEGPAFPNPQKKINHVAYASIITAMTHLMVRDHMFVIQTKNEAHSSQKLVQLFYAFSKEMVCVVPTSLTPTDEELCIKLWSSLSGISGVIGKILANTCSVAHLVSGKLPSQNIDQLKTPSNRPFPKKVKRMLISISKGNKELEIKLLSGVPNIGKKLAAEILKDHALLFFLNQPVECLANIQIAQKTRTIKLGMKRAEAIHYFLNWCGSAHVTVDSQNITEASRPTMQVATQPAATQPLHKVSDDASSDASSPTGHQTLSKEMSLNTVRC
What is the function of this protein?
Plays a role in the inhibition of type I interferon signaling pathway.  Mechanistically, specifically interacts with 2',3'-cGAMP and cleaves it via its phosphodiesterase activity.  In turn, prevents 2',3'-cGAMP interaction with host ER-resident STING1 leading to inhibition of downstream signaling pathway and type I interferon production.
What are the official names of this protein?
ERCC4 domain-containing protein EP364R, pEP364R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus EP364R family.
Protein: DAPB_YERPS
Sequence: MTDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNVIVGDDLSQLTDNFDVLIDFTRPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAADIGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIADAMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSRMTFAHGAVKSAIWLGKHDNGLFDMRDVLNLNEL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4784_RHIME
Sequence: MLKWALIFFVISLIAGFLGFSGVSAATAGIAKILFYIAVIIFLVFLVLALAVGGAVT
What are the official names of this protein?
UPF0391 membrane protein RB0084.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ANR60_HUMAN
Sequence: MTRGRAWGMRRAAAGAGGARAAGPTGGASRLHPNAGRRSGARAGAQGCGGPRVGSADSRALPAQPLACARGRSQRLVCDPKAASALPDLAPDVFVLRVRLEETGEMFRVANCRGDMTVRELKEELDLMVGIPFNLQRLQYLDEGVLMDDTTLKFHDVVPGGIISLCIWHHDGWTELVLAAVEGDPSKLSCLGLTEDSFYRTANSEHFEGEKWKHWTSQRAFVALYVASHRGHFDAVQYLLEHGASCLSRSPLGRTPLHVAAAMGRSDCIILLLQHGASIHDRDAKGETPISIAHRLNHTLSERQMVLLHRIAKSGIRDLNDLVMKNALQRVKSGFRSEKMTMTPH
What are the official names of this protein?
Ankyrin repeat domain-containing protein 60.
Protein: TYSY_STRP2
Sequence: MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAFSEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDTGTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMFDVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNLHIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.