PharMolix/UniProtQA huggingface dataset:
Protein: ACTB_TRIVU
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells.  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.  Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: HBB2_MOUSE
Sequence: MVHLTDAEKSAVSCLWAKVNPDEVGGEALGRLLVVYPWTQRYFDSFGDLSSASAIMGNPKVKAHGKKVITAFNEGLKNLDNLKGTFASLSELHCDKLHVDPENFRLLGNAIVIVLGHHLGKDFTPAAQAAFQKVVAGVATALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-2, Beta-2-globin, Hemoglobin beta-2 chain, Hemoglobin beta-minor chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL4_OENOB
Sequence: MTKVALYKQDGTQAGEVELADSIFAIEPNEAVVTDAVLMQRASLRQGTHSVKNRSTVSGGGRKPWRQKGTGNARQGSIRAPQWRGGAISMGPIPRPYAYKINRKAYRLALKSVLSDKVSAKNFVIIDELNFEKPSTKAIADSLNKLEATKKTLLVVDDANENAKLSARNLPNVQVTTASGVNVYDLVKAQKVVIVQSAVKQVEEVLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: THIG_XANC8
Sequence: MTLSAPSDALVIAGKPYRSRLLTGTGKFKDLDETRLATEAAAAQIVTVAIRRVNIGQDPNAPSLLDVLPPDRYTLLPNTAGCYTAEDAVRTCRLARELLDGHNLTKLEVLGDERTLYPDVVQTLKAAEQLVADGFEVMVYTSDDPILAKRLEEIGCVAVMPLAAPIGSGLGIQNKYNLLEIIENAKVPIIVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPILMASAMRKAIEAGREAFLAGRIPRKRYASASSPVDGVIG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_RICFE
Sequence: MSKPTREEAKEAVRTLLKFIGEDPTREGLLKTPDRVVNSYTEIFSGYGKDVAEILNTKFYDTCNFQDFILLKDIKFTSFCEHHMLPFIGTVDIAYIPDNCIVGISKLARIVNAFSKRLQIQEKMTVQIAESVQENLKPLGVAVKISALHSCMSMRGVMQDNSVMNTMHYTGIFAEQQKYRYDFLNLTAKR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: Y031_BACCZ
Sequence: MEKNKHCFYVVECSDGSYYAGYTNHIEKRIGTHNSGRGAKYTRARLPVVLKYVEFHEDKRTAMQAEYYFKQLNRKQKEEYMQKGERYVATKKLSTK
What are the official names of this protein?
UPF0213 protein BCE33L0031.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: RL331_MYCTO
Sequence: MARTDIRPIVKLRSTAGTGYTYTTRKNRRNDPDRLILRKYDPILRRHVDFREER
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: YBAE_ECOLI
Sequence: MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTLLRQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEQALETGKQQDVLELAQLAPGELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDNNTQRPIGDLAHHWETSTDGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQLFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTAELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQVSSGISLGFCYLTLRKSPRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWTIPHWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTTLQAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQIMPDEENRFNALKAVFSQLMTDATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
What are the official names of this protein?
Uncharacterized protein YbaE.
Protein: FER_PANGI
Sequence: ATYYKVKLLTPEGEKEFECPDDVYILDNAEEIGIDLPYSCRAGSCSSCAGKVVSGKVDNSDNSFLNDDNMDAGYVLTCHAYANSDVVIETHKEEEV
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRDB_LISIN
Sequence: MNRLAVEIPGLSLKNPIMPASGCFGFGQEYSKYYDLNELGAIMAKAVTPEPRLGNPTPRVAETASGMLNAIGLQNPGLEHVLAHELPFLEQFETPIIANVAGATEDDYVQVCSRIGESKAVKAIELNISCPNVKHGGIAFGTDPEVAHRLTKAVKSVASVPVYVKLSPNVADIISIAQAIEAAGADGLTMINTLLGMRIDLKTRKPVIANGTGGLSGPAIKPVAIRMIHQVRAVSNIPIIGMGGVQTVDDVLEFLIAGADAVAVGTMNFTDPFICPKLITELPKRMDELGISSLQELKKELLNQ
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_YERPY
Sequence: MDYTLTRIDPNGENDRYPLQTQETVSGDPLEQHVHRSVYMGKLENAMHDMVNWGRKNSLWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADFMVVAGTCFTKMAPVIQRLYEQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFLPVDVYIPGCPPRPEAYMQALLLLQESIGKERRPLSWVVGDQGVYRANMQPERERKHAERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UXUA_THENE
Sequence: MKLVFRWFGEKHDTVTLEQIRQIPGVEGVVGALFDIPVGEVWPLEEIMKLKETVERAGLKLEVIESVNVHEDIKLGLPTRDRYIENYKETIRNLAKAGVKVVCYNFMPVFDWMRTDLHKKLPDGSETMEYDHSLIEGVTPDELIERVKEGSEGFVLPGWEWDRLEKLRETFELYKNVDEEKLFENLVYFLERVIPVCEECDVKLAIHPDDPPWSIFGLPRIITNKENIERLLKAVDSPYNGITLCMGSLGANPENNIPEMIRYFGKMGRIHFAHVRNLKFTGEKSFYETAHPSFCGSHDLFEVMKAFHDIGYEGYIRPDHGRLIWGEKARPGYGLYDRALGATYILGLWEAISKMKERYC
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: RL30_BACSU
Sequence: MAKLEITLKRSVIGRPEDQRVTVRTLGLKKTNQTVVHEDNAAIRGMINKVSHLVSVKEQ
What are the official names of this protein?
50S ribosomal protein L30, BL27.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ISPG_LYSSC
Sequence: MSEICHRSNTRPVRVGNLTIGGSNELFIQSMCTTKTHDVEATVAEILRLEEAGCQIVRVAVPDERAADAIAEIKKRIHIPLVADIHFDYRLALKAIENGIDKVRINPGNIGRKEKVEAVVNAAKAKGIPIRIGVNAGSLERHILEKYGYPTADGMVESALHHIKILEDLDFHDIIVSMKASDVNLAIEAYEKAAKAFNYPLHLGITESGTLFAGTVKSAAGLGAILSKGIGNTLRISLSADPVEEIKVARELLKSFGLASNMATLISCPTCGRIEIDLISIANEVEEYISKLNVPLKVAVLGCAVNGPGEAREADIGIAGARGEGLLFMKGKTVRKVPEETMVEELKKEIDKLAAEMEEKRAAEEVQKANA
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: FTSB_HERAR
Sequence: MRLIILCLAALVLLIQFPLWLGKGGWLRVWDLDQQVIAAQKKNDELRARNAKLNSEVQDLKEGTGAVEERARYELGMIKENEIFVQVLDPNKKSSFVSIPPPKIEPKEKR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: Y18_BPT3
Sequence: MTLRECCDWCAAKWNQAIEDGDKAAADAYQQLYALWERRFKEA
What are the official names of this protein?
Uncharacterized gene 1.8 protein.
Protein: VATD_HALSA
Sequence: MAQDIKPTRKNLMEIEDRIDLSERGHDTLEQKRDGLIMEFMDILDQSQDVRSGLEGDYETAQQKINMARAMEGDVAVSGAAAALEEYPEITVESMNIMGVVVPQIESTKVKKSFDKRGYGILGTSARIDEAADAYEELLESIVLAAEVETAMKKMLTEIETTKRRVNALEFKLLPELHEGKEYIDQKLEEKEREEMFRMKKVKDKKEAQEEAADEAAAAESTGA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: GSPB_AERHY
Sequence: MSTLLKALRRAEQPQFTPHIPAMGLPVTQEEEQNRRWIWWLLAPLALLMGAGANYGWHLLNNRPIEKTVEVKEVVTPPFVRVEPRPMITRPLPPPLPEPVVRPRVTPNDSAPAANGSQGLAERIMNALNSTPLMEETAPQAQSESQAMPISALPLELKQRVPPLAYGSHVFSSNPAKRAVMLNGREFREGSEVAPGVTLIAIAQDYIILQVAGQNVSLKALQDWRG
What is the function of this protein?
Involved in a general secretion pathway (GSP) for the export of proteins.
What are the official names of this protein?
General secretion pathway protein B.
What is the protein family that this protein belongs to?
Belongs to the ExeB/OutB/PulB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MEPA_SHIF8
Sequence: MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVSTLWKPEIFSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPSGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HSLU_PHOLL
Sequence: MSEMTPREIVSELDKHIIGQDKAKRAVAIALRNRWRRMQLDETLRYEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRLQSIEQNRYRAEELAEERILDVLIPPAKNNWGQTETQVEPSAARQAFRKKLREGQLDDKEIEIDVATTPVGVEIMAPPGMEEMTNQLQSMFQNLAGQKHKSRKLKIKDAFKLLIEEEASKLVNPEELKQQAIDSVEQHGIVFIDEIDKICKRGQTSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVASPSDLIPELQGRLPIRVELQALTTKDFERILTEPSASLTEQYKALMETEGMIISFTDDGISKIAESAWQVNESTENIGARRLHTVLERLIEDISFEASERRGQSVDIDADYVKKHLDELVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y076_NPVOP
Sequence: MHLYLLLGALAVFSLVYDKKENGIVFYFLILVLVFVLISPAFISKNTESAANDLPSHKAKSVRKKLEIEQALDAILNKNTSSLD
What are the official names of this protein?
Uncharacterized 9.4 kDa protein.
Protein: PIN3B_ORYSJ
Sequence: MISWHELYMVLSAVVPLYVAMMVAYGSVRWWGVLTPEQCSGINRFVAVIAVPLLSFHFISSSDPYAMNLRFVAADTLQKVLVLAALAAWSRFPARFVPPAWPPLDCSITLFSVSTLPNTLVMGIPLLVSMYGPYSGDLMVQIVVLQSIVWYTLLLFLFEFRAARVLIAAQFPDTAASIAAVHVDPDVVSLEGSQAEAHAEVAPDGRLRMVVCRSSVSRRSAAAAATPRASNLTGVEIYSISSSRNATPRGSTFTLADIPGHQPPNSALRASSFGAADLFSLHSSSRQHTPRPSSFDEHAAARARASATVAPTNDLKDTHMIEWSSGASAASEVTGLPVFRSGRETRRLVPSDAPSIASSRVIRPPPGATGGERAASFNKAVGGQDELAKLEAGAKTEQQTTAVTTTTKGGGAAGAERARGQQNAPAGVMLRLILTTVWRRLIRNPNTYASLIGLTWSLIAFRFHITMPIIVAKSISILSDAGLGMAMFSLGLFMATQPKIIACGYSVAAASMGVRFFFGPAIMAAASAAVGIRGTLLRIAIVQAALPQGIVPFVFAKEYNLHATILCTLVIFGMLIALPITLVYYIILGLL
What is the function of this protein?
May act as a component of the auxin efflux carrier.
What are the official names of this protein?
Probable auxin efflux carrier component 3b, OsPIN3b, OSPIN10b.
What is the protein family that this protein belongs to?
Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COAE_TREDE
Sequence: MDSVLNGRQSRQSLDAPSEPILIGLSGPSCSGKNTASTILQDYGFYCIDADAVSRKVFTEHEKEILNLFQAEAEKRGINLKNENGIDKKAFALLVFSDEELLKKHEAFILPIIEEKIWEEIKRAFTEKPERPILLNAPTLHKTSFIKKCLFILYIDAPFILRLIRAKKRDRLPLKNIWLRFSKQKKFFSQYFFLNADTIVVKNFWSSASLKRKLLQEVKKRGF
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF2_MANES
Sequence: MKGHQLKSWIFELREILREIKSVGSFIHIFFHQERFIKLLDSRIWSILLSRNSQGSTSNRYFTIKGVVLFVVVVLIYRINNRKMVERKNLYLTGLLPIPMNSIGPRNDTLEESFWSSNINRLIVSLLYLPKGKKISESSFLDPKESTWVLPITKKCIMSESNWGSRWWRNWIGKKRDSSCKISNETVAGIEISFKEKDIKYLEFLFVYYMDDPIRKDHDWELFDRLSPRKGRNIINLNSGQLFEILVKDWICYLMFAFREKIPIEVEGFFKQQGAGSTIQSNDIEHVSHLFSRKKWAISLQNCAQFHMWQFRQDLFVSWGNNPHESDFLRNISRENWIWLDNVWLVNKDRFFSKARNISSNIQYDSTRSSFVQGRNSSQLKGSSDQSRDHFDSISNEDSEYHTLINQRKIQQLKERSILWDPSFLQTERTEIESDRFPKCLSGYSSMSRLFTEGEKEMNNHLLPEEIEEFLGNPTRSIRSFFSDRSSELHLGSNPTERSTRNQKLLKKEQDVSFVPSRRSENKEIVNIFKIITYLQNTVSIHPISSDPGCDMVLKDELDMDSSNKISFLNKNPFFDLFHLFHDRNGGGYTLHHDFESEERFQEMADLFTLSITEPDLVYHKGFTFFIDSYGLDQKQFLNEVFNSRDESKKKSLLVLPPIFYEENESFYRRIRKKWVRISCGNDLEDPKQKIVVFASNNIMEAVNQYGLILNLIQIQYSTYGYIRNVLTQFFLMNRSDRNFEYGIQRDQIGNDTLNHRTIMKYTINQHLSNLKQSQKKWFDPLIFIFLSRTERSMNWDPNAYRYKWSNGSKNFQEHLEHFISEQKSRFLFQVVFDRLRINQYSIDWSEVIDKKDLSKSLRFFLSKLLLFLSKFLLFLSNSLPFFFVSFGNIPIHRSEIHIYELKGPNDQLCNQLVEPIGLQIVHLKKLKPFLLLLDDHDTSQKSKFLINGGTISPFLFNKIPKWMIDSFHTRNNRRKSFDNTDSYFSMISHDQDNWLNPVKPFHRSSLISSFYKANRLRFLNNLHHFCFYCNKRFPFYVEKARIKNYDFTYGQFLNILFIRNKIFSLCGGKKKHAFLERDTISPIESQVSNIFIPNDFPQSGNERYNLYKSFHFPIRSDPFVRRAIYSIADISGTPLTEGQIVNFERTYCQPLSDMNLSDSEGKNLHQYLNFNSNMGLIHTPCSEKYLPSEKRKKRSLCLKKCVEKGQMYRTFQRDNAFSTLSKWNLFQTYMPWFLTSTGYKYLNLIFLDTFSDLLPILSSSQKFLSIFHDIMHGSDISWLIFQKRLWKICRNLISEISSKCLHNLLLSEEMIHRNNEPPLISTHLRSPNVREFLYSILFLLLVAGYLVCTHLLFVSHAYSELQTEFEKVKSLMIPSYMIELRKLLDRYPTSELNSFWLKNLFLVALEQLGDFLEEMRGSASGGNMLWGGGPAYGVKSIRSKKKFWNINLIDLISIIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVNGDWIDDKIESLVANSDWIDDKEREFLVQFSTLTTEKRIDQILLSLTHSDHLSKNDSGYQMIEEPGAIYLRYLVDIHKKYLMNYEFNTPCLAERRIFLAYYQTTTYSQTSCGVNSFHFPSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYLPFVTVFLNKFLNNKPKGFLIDDSDDIDDSDDIDDSDDIDASDDIDVSDDIDVSDDDIDRDFDFDTELEFLTTMDALTIDMMPEIEINRFYITLQFELAKAMSPCIIWIPNIHDLDVNESNYLSLGLLVNYLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRFLIPQQRKHFFTLSYTRGFHLENKMFHTNGFGSITMGSNVRDLVALTNEALSISITQKKSIIDTNIIRSALHRQTWDLRSRVRSVQDHGIFFYQIGRAVAQNVFLSNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKKLTILLYLLSCSAGSVAQDLWSLPGPDEKNGITYYGLVENDSDLVHGLLEVEGALVGSSRTEKDCSQFDNDRVTLLLRPEPRSPLDMMQNGSCSILDQRFLYEKYESEFEEGEGEEVLDPQQIEEDLFTHIVWAPRIWRPWGFLFDCIERPNELGFPYWARSFRGKRIIYDEEIIYDEEIIYDEEDELQENDSEFLQSGTMQYQIRDRSSKEQGFFRISQFIWDPADPLFFLFKDQPFVSVFSHREFFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKRFELLIHRQRWLRTNSSLSNGFFRSNTLSESYQYLSNLFLSNGTLLDQMTKALLRKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y1078_LISMC
Sequence: MEYSYPLNPDWTTEEMTIVVQFLEAIERAYEKGIDTLELKEKYRAFKQVVPAKGEEKRIGIDFEKASGYSAYKVMQLVKNATTSKIKMQP
What are the official names of this protein?
UPF0223 protein Lm4b_01078.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: RL2_ALCBS
Sequence: MAIVKCKPTSPGRRFVVKVVNEDLHKGAPYAPLLEAKAKNGGRNNNGRITTRHKGGGHKQKYRVIDFRRNKDGIAGVVERLEYDPNRTAHIALVKYLDGERRYILAPKGLKAEDRIQSGEDAPIKLGNALPLRNIPLGSTIHNVEMKPGKGGQIARSAGTSVQLLAKDGQYVTLRLRSGEMRKVHADCKATIGEVSNSEHSLRSLGKAGAKRWRGVRPTVRGAAMNPVDHPHGGGEGRSSGGRHPVTPWGVPTKGYKTRTNKRTTKMIVRDRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y612_ARCFU
Sequence: MFVNGTPVIEIVLSNPLLSVKFPESGSVLAVIDTGYEGFAVVPQDIFKKLRLDELSQHKRALTLPTERLIESTGSYARIIIPELKTFRDGFVETTDGVDEIVLGTEFLEGFKLVLDYCTRSFEISSCW
What are the official names of this protein?
Uncharacterized protein AF_0612.
Protein: HS104_YEAST
Sequence: MNDQTQFTERALTILTLAQKLASDHQHPQLQPIHILAAFIETPEDGSVPYLQNLIEKGRYDYDLFKKVVNRNLVRIPQQQPAPAEITPSYALGKVLQDAAKIQKQQKDSFIAQDHILFALFNDSSIQQIFKEAQVDIEAIKQQALELRGNTRIDSRGADTNTPLEYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEPGIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTAGAKYKGDFEERFKGVLKEIEESKTLIVLFIDEIHMLMGNGKDDAANILKPALSRGQLKVIGATTNNEYRSIVEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVTAAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSKPEELDSKERQLQLIQVEIKALERDEDADSTTKDRLKLARQKEASLQEELEPLRQRYNEEKHGHEELTQAKKKLDELENKALDAERRYDTATAADLRYFAIPDIKKQIEKLEDQVAEEERRAGANSMIQNVVDSDTISETAARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRSGLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEKYAVSKLLGTTAGYVGYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLDDGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAVRQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKLNLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKETVNVVLKKGKSRDENVPEEAEECLEVLPNHEATIGADTLGDDDNEDSMEIDDDLD
What is the function of this protein?
Required, in concert with Hsp40 (YDJ1) and Hsp70 (SSA1) and small Hsps (HSP26), for the dissociation, resolubilization and refolding of aggregates of damaged proteins after heat or other environmental stresses.  Extracts proteins from aggregates by unfolding and threading them in an ATP-dependent process through the axial channel of the protein hexamer, after which they can be refolded by components of the Hsp70/Hsp40 chaperone system.  Substrate binding is ATP-dependent, and release of bound polypeptide is triggered by ATP hydrolysis.  Also responsible for the maintenance of prions by dissociating prion fibrils into smaller oligomers, thereby producing transmissible seeds that can infect daughter cells during mitosis and meiosis.  Loss of HSP104 can cure yeast cells of the prions [PSI+], [URE3] and [PIN+].  Excess HSP104 can also specifically cure cells of [PSI+].
What are the official names of this protein?
Heat shock protein 104, Protein aggregation-remodeling factor HSP104.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus in an importin KAP95- and KAP121-dependent and an exportin XPO1-dependent manner. Accumulation in the nucleus is enhanced by severe heat shock. In the cytoplasm, concentrates on a perivacuolar compartment, the 'insoluble protein deposit' (IPOD), in which terminally aggregated proteins are sequestered. It is also found, to a lesser extent, at a 'juxtanuclear quality control' (JUNQ) compartment, where soluble ubiquitinated misfolded proteins accumulate.
Protein: CP2F2_MOUSE
Sequence: MDGVSTAILLLLLAVISLSLTFSSRGKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNIFPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSPRDFIDCFLTKMAQEKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDDNHSFKKSPAFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDPEDIDLTPLSSGLGNLPRPFQLCMHIR
What is the function of this protein?
Involved in the regio- and stereoselective transformation of naphthalene to trans-1R-hydroxy-2R-glutathionyl-1,2-dihydronaphthalene in the presence of glutathione and glutathione S-transferases.  It specifically catalyzes the production of a very reactive and potentially toxic intermediate, the 2R,2S arene oxide, that is associated with necrosis of the unciliated bronchiolar epithelial cells or club cells in lung.
What are the official names of this protein?
Cytochrome P450 2F2, CYPIIF2, Cytochrome P450-NAH-2, Naphthalene dehydrogenase, Naphthalene hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: DAPT2_TRIV2
Sequence: MQFAKRLEKIPPYLFAEINRKREALIAQGVDIINIGVGDPDKPTPAHILQAMREAIDEASNHNYPPYEGTQEFREAAVKWMERRFGVVDLNPNTEVVSSIGSKEAIHNTFLAFVEAGDYTLIPDPGYPVYRTSTIFAGGEPFTMPLKAENKFLPDLDLIPEEVARKAKMLWVNYPNNPTGALATLEFFEELVAFCQQHSILLCHDHAYSEMAYDGYKPPSVLQIPGAKDIAIEFHSLSKSYNMTGWRIGFAVGNAYAIQGLSQVKTNVDSGVFKAIQKAAIAAYNTDEVELQAVMSVYQNRRDIIVKGLQSLGWPIEPPKATLYVWVPVPPGYTSTEFTTLLLDKCGIVVPPGVGYGVSGEGYFRIALTICEERLHEAIQRMQDAGIRYS
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase 2, DAP-AT 2, DAP-aminotransferase 2, LL-DAP-aminotransferase 2.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.