PharMolix/UniProtQA huggingface dataset:
Protein: GR101_LYMST
Sequence: MATMSGTTIVCLIYLTTMLGNSQGVNLKIESPSPPTLCSVEGTFHCDDGMLQCVLMGSKCDGVSDCENGMDESVETCGCLQSEFQCNHTTCIDKILRCDRNDDCSNGLDERECDIYICPLGTHVKWHNHFCVPRDKQCDFLDDCGDNSDEKICERRECVATEFKCNNSQCVAFGNLCDGLVDCVDGSDEDQVACDSDKYFQCAEGSLIKKEFVCDGWVDCKLTFADELNCKLCDEDDFRCSDTRCIQKSNVCDGYCDCKTCDDEEVCANNTYGCPMDTKYMCRSIYGEPRCIDKDNVCNMINDCRDGNVGTDEYYCSNDSECKNFQAAMGFFYCPEERCLAKHLYCDLHPDCINGEDEQSCLAPPKCSQDEFQCHHGKCIPISKRCDSVHDCVDWSDEMNCENHQCAANMKSCLSGHCIEEHKWCNFHRECPDGSDEKDCDPRPVCEANQFRCKNGQCIDPLQVCVKGDKYDGCADQSHLINCSQHICLEGQFRCRKSFCINQTKVCDGTVDCLQGMWDENNCRYWCPHGQAICQCEGVTMDCTGQKLKEMPVQQMEEDLSKLMIGDNLLNLTSTTFSATYYDKVTYLDLSRNHLTEIPIYSFQNMWKLTHLNLADNNITSLKNGSLLGLSNLKQLHINGNKIETIEEDTFSSMIHLTVLDLSNQRLTHVYKNMFKGLKQITVLNISRNQINSIDNGAFNNLANVRLIDLSGNVIKDIGQKVFMGLPRLVELKTDSYRFCCLAPEGVKCSPKQDEFSSCEDLMSNHVLRVSIWVLGVIALVGNFVVIFWRVRDFRGGKVHSFLITNLAIGDFLMGVYLLIIATADTYYRGVYISHDENWKQSGLCQFAGFVSTFSSELSVLTLSTITLDRLICILFPLRRTRLGLRQAIIVMSCIWVLVFLLAVLPLLGFSYFENFYGRSGVCLALHVTPDRRPGWEYSVGVFILLNLLSFVLIASSYLWMFSVAKKTRSAVRTAESKNDNAMARRMTLIVMTDFCCWVPIIVLGFVSLAGARADDQVYAWIAVFVLPLNSATNPVIYTLSTAPFLGNVRKRANRFRKSFIHSFTGDTKHSYVDDGTTHSYCEKKSPYRQLELKRLRSLNSSPPMYYNTELHSDS
What is the function of this protein?
Might directly transduce signals carried by large extracellular lipoprotein complexes into neuronal events.
What are the official names of this protein?
G-protein coupled receptor GRL101.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXK_XANC5
Sequence: MSKRGTRTPGYWYDNTPIPLPARILAPVYGAAIALRRALYRRGWRRRHRVPVPVIVVGNVTAGGTGKTPLTIALVVKLQEAGWTPGVASRGYGRDDAGTARWVEADTPVALGGDEPVLIAWKTGARVRVDSDRLAAARALVEAGCDIVICDDGLQHYRLARDVEIEVVDGQRRYGNGRLLPAGPLREPAARARDCDFRVVNLGQASATAAPQVPDDAGFGEWQMRLSIDSVQPMDGKRAQPLSMLAGQRVHAVAGIAHPERFFAMLRARGIGVVPHAFPDHHVYRAADFSFGSRLPVLMTEKDAVKCRPFADEWLYSVPLKAELPAAFWVSLLDRLNKLASRQGV
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: YKQ9_YEAST
Sequence: MGVLLFLYDPTCQRAYLIVSLVFQCSIYTTIISHNSCPQRFTGIFINQNASSISECNGGAILSAHVTLFRPYDNCVTNITFFDTVGVGCPRNVLSQGLCFLYNTDYSVSNHCRTLGGPFPYYFNTFC
What are the official names of this protein?
Putative uncharacterized protein YKL169C.
Protein: RL13_LARHH
Sequence: MKTFSAKPHEVKRDWFVVDATDKVLGRLAAEIARRLRGKHKPEYTPHVDTGDYIVVVNADKLRVTGNKALDKKYYRHSGYPGGIYERTFTELQNEFPERVLEKAVKGMLPKGPLGYAMIKKLKVYAGAEHPHTAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GARD_BACSU
Sequence: MAMNLRKNQAPLYIKVHEIDNTAIIVNDGGLPKGTVFSCGLVLEEDVPQGHKVALTDLNQGDEIVRYGEVIGFADETIKRGSWIREALVRMPAPPALDDLPLANRVPQPRPPLEGYTFEGYRNADGSAGTKNILGITTSVQCVVGVLDYAVKRIKEELLPKYPNVDDVVPLHHQYGCGVAINAPDAVIPIRTIQNLAKHPNFGGEVMVIGLGCEKLLPERIASENDDDILSLQDHRGFAAMIQSILEMAEERLIRLNSRTRVSCPVSDLVIGLQCGGSDAFSGVTANPAVGYAADLLVRAGATVLFSEVTEVRDAIHLLTPRAVSEEVGQSLIKEMKWYDSYLRRGDADRSANPSPGNKKGGLSNVVEKALGSVAKSGTSPISGVLGPGERAKQKGLLFAATPASDFVCGTLQLAAGMNLQVFTTGRGTPYGLAAAPVLKVSTRHSLSEHWADLIDINAGRIATGEASIEDVGWEIFRTILDVASGRKQTWADRWGLHNDLCLFNPAPVT
What is the function of this protein?
Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG).
What are the official names of this protein?
Probable galactarate dehydratase (L-threo-forming), GalcD.
What is the protein family that this protein belongs to?
Belongs to the UxaA family.
Protein: IFNA2_HORSE
Sequence: MALPFSLLMALVVLSCHSSCSLGCDLPHTHSLGNTRVLMLLGQMRRISPFSCLKDRNDFGFPQEVFDGNQFRKPQAISAVHETIQQIFHLFSTDGSSAAWDESLLDKLYTGLYQQLTELEACLSQEVGVEETPLMNEDSLLAVRRYFQRIALYLQEKKYSPCAWEIVRAEIMRCFSSSTNLQQS
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.
What are the official names of this protein?
Interferon alpha-2.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPS_HALMA
Sequence: MLSRGKRLGYAAYERLLQWELSGTPDHVAVIMDGNRRYAEKQGTKKQEGHKEGAQTTEALLNWCDELGIREVTLYTFSTENFDRDPEEREHIFDLVEQKLRTFADADRVHEAGVCIRAIGETEMLPERVRDAIDYAEGRTAQYDQLNLNIALAYGGRAELLGAARDVAAAVENETLDPTDVSAETIEERLYEGPTRDVDLIVRTGGDERTSNFLPWHANGNEAATFFCTPYWPEFRKVDFLRAIRTYQNREDSWRTTRAERSLALVRAIEQSELPTAKRMLGRFRDALPSTEREQLDEEYDLAD
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP).  It is probably the precursor of glycosyl carrier lipids.
What are the official names of this protein?
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific), Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: GPDA_STRZP
Sequence: MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTYHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAIIMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CY550_THAWE
Sequence: ALSLATPRRDNINALVDYLKNPTSYDGLDSIAEIHPSIKSADIYPRMRSLTDDDLYAIAGHIMLQPKVVSEKWGGGKIYF
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: ODO2_RAT
Sequence: MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGVSLCQGPGYPDSRKMVINNSSVFSVRFFQTTAVCKNDVITVQTPAFAESVTEGDVRWEKAVGDAVAEDEVVCEIETDKTSVQVPSPANGIIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPATAYKAAPEAPAAPPPPVAPVPTQMPPVPSPSQPPSSKPVSAIKPTAAPPLAEAGAAKGLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEVDMSNIQEMRARHKDAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDATKEVVYRDYIDISVAVATPRGLVVPVIRNVETMNYADIERTINELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHGIFDRPVAVGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL
What is the function of this protein?
Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex (By similarity).  The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (By similarity).  The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion.  A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity).
What are the official names of this protein?
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial, 2-oxoglutarate dehydrogenase complex component E2, OGDC-E2, Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex, E2K.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Note=Mainly localizes in the mitochondrion. A small fraction localizes to the nucleus, where the 2-oxoglutarate dehydrogenase complex is required for histone succinylation.
Protein: RNY_CAMJD
Sequence: MIESLIALIAAIVGLGIGYLVAKKINDAKYEIFVEQAKAKAKAIEYEAELILKDAKNSILNAELEVKKKYEEKTHKIQKDFNQKLDDLFKKEQKLQQEEEKLKEDKEYLCKSQKHIQDLQSDVDKLKNKYQEKLDDVLKILEHSTRLTQNEAKEIILKKVEENSREQIAHIVRKYEEEAKNEAKRKANFIIAQATSRFAGEFAAERLINVINIKNDELKGRIIGKEGRNVKTLEMVLGVDIIIDDTPGAIIVSCFNLYRRAIATKVIELLVEDGRIQPARIEEIHEKVCKEFDSAILEEGEIIVMDLGLNKIHPEIVKLIGKLKYRASYGQNALAHSLEVAHLAGIIAAECGGDENLARRAGILHDIGKALTHDFEGSHVDLGAELCNRYKEHPVVINAIYAHHGHEEATSIESAAVCAADTLSAARPGARREVLEAFLKRVSELEDIAKSKEGIKNAYAINAGREIRIIANAQLVNDDESVLLAKEIAAEIQEKMQYPGEIKVNVIRELRAIEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SAHH_CUPNH
Sequence: MNAVTDLKQDYLVADINLAGWGRKEIAIAETEMPGLMAIRDEFAAAQPLKGARIAGSLHMTIQTAVLIETLKALGADVRWASCNIFSTQDHAAAAIAAGGTPVFAFKGESLKEYWDFTHRIFDWADGGTPNMILDDGGDATLLLHLGARAEKDQSVIAKATSEEETYLFAAIKEKLAKDPSWYSRNLAAIRGVTEETTTGVHRLYQMAQKGELRFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKVAIVAGYGDVGKGSAQALRALSAQVWVTEIDPICALQAAMEGYRVVTMDYAAEHGDIFVTCTGNYHVITHDHMAKMKDQAIVCNIGHFDNEIDIASIEKYEWDEIKPQVDHVKFPDGKKLIILAKGRLVNLGCATGHPSYVMSSSFANQTIAQIELWQERDSGKYPVGVYTLPKHLDEKVARLQLRKLNAQLTELTEQQAAYIGVKKEGPYKADHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SETD6_HUMAN
Sequence: MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVSERAGGRRTRGGARAALTSPPAQVAVSRQGTVAGYGMVARESVQAGELLFVVPRAALLSQHTCSIGGLLERERVALQSQSGWVPLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIRSEYQSIVLPFMEAHPDLFSLRVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPVMVPAADILNHLANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGSLTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS
What is the function of this protein?
Protein-lysine N-methyltransferase.  Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity (PubMed:21131967, PubMed:30189201, PubMed:21515635).  Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (PubMed:23324626).  Required for the maintenance of embryonic stem cell self-renewal (By similarity).  Methylates PAK4.
What are the official names of this protein?
N-lysine methyltransferase SETD6, SET domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
Protein: MUTS2_ALKOO
Sequence: MNERSLRVLEYNKIIHMLEDKCTSSLGREKLKELKPISNFEQITTWQKETSEAQSILIHRGNIPLGGIHDVSQYLRRTEIGSYLDPGQLLQLKETLAAARRMKTFLKDDKKESTYPIIQELGNNISSLKHIEDKIELCIISETELSDNASPELRNIRRQISSKNDAIRNKLNSIITSASNQKYLQDPIITMRQDRYVVPVKQEHRGNIPGLIHDQSSSGATIFVEPMAVVELNNQLKELRLKEQVEIERILMEIAAMIAERSDDIKSNQIILKELDFIFAKGKLSVEMRAVEPVLNTNKKISIKNGRHPLLPSNKVVPNTMWLGEDFHTLVITGPNTGGKTVTLKTLGLLTLMAQSGLHVPADYGTKLAIFDQVFADIGDEQSIEQSLSTFSSHMTNIVNIMDNVTEQSLVLFDELGAGTDPTEGAALAMAILNSLREMGTVTVATTHYSELKQYALSTEGVENASVEFDVNTLSPTYKLLIGVPGKSNAFEISRKLGLSDFLIQRSKELLTREDIQFEDLLQNIEKNRSTAEKEKDEAARLRMETQKLREEYYEKKQQLQTQKEKLISDAKREAYKIVKQAKLDADEIVENLKTLRAELEEKEMNKKIEEARKNLSDQMGKLAENMGEKLVLKTNKKPPKNLKIGESVNILSLNQIGYVILPEDANGEVQLQVGIMKVNMHVSNLERIKEEKDTKKTGVGKIVKSKAENIKMEIDVRGQNLEEAMLNVDKYLDDAYIAGLTHVTIIHGVGTGVLSAGLKQMLKKHKHTKSFREGEYGEGGMGVTIVHLK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: PELA_ASPTN
Sequence: MKFPAFITAIISIASLSSAISVSGAAEGFAKGVTGGGSATPVYPSTISELVSYLKDSQPRVVVLTKTFDFRGSEGTTTGTGCAPWGTASNCQLAINKDNWCTNYQPNAPSASVSYDNAGVLGITITSDKTLIGQGSSGVIKGKGIRIVSGAKNVIIQNIAITDINPKYVWGGDAITLNNCDMVWIDHVTTARIGRQHLVLGTSASNRVTVSNSYFNGVSDYSATCNGYHYWGIYFAGSNDMVTLKGNYIYHMSGRSPKVQSNTLLHAVNNYWYDISGHAFEIGAGGYVLAEGNVFQNVPTILEEDDGQLFTSPNSNTNQVCSTYLGHVCQVNGFGSSGTFSSADTGFLVNFQGKNVASASAYTVAQSSVPSNAGQGKL
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
What are the official names of this protein?
Probable pectin lyase A, PLA.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBT_CERJA
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKMK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MDTD_CROS8
Sequence: MTDLPQNVRWQLWIVAFGFFMQALDTTIVNTALPSMAASLGESPLRMHMVIVSYVLTVAVMLPASGWLADRVGVRNIFFTAIVLFTLGSLFCAQSSTLNELVAARVLQGIGGAMMVPVGRLTVMKIVPRDQYMAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINLPVGIAGAAATLWLMPNYTMQTRRFDFSGFLLLAFGMAALTIALDGYRSTGLSPAGLGALVAGGSAATLLYLWHARGNERALFSLRLFNTRTFSLGLFGSLCGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMMPMVLGSMGIKRIVVQVVNRFGYRRVLVASTLALALVTLLFMGVALAGWYWLLPVVMLFQGMVNSVRFSTMNTLTLRDLPDEMASSGNSLLSMVMQLSMSLGVSIAGLLLGAFGHNQLAADSGDAHGIFFWTYLCMALIIALPALVFARVPDDISKNAVIARRKRSAS
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDH_SHEAM
Sequence: MKVAVLGAAGGIGQALALLLKTQLPAGSKLSLYDIAPVTPGVAVDLSHIPTAVEVKGFCGEDPTPALEGADVVLISAGVARKPGMDRSDLFNINAGIVRNLIEKVAATCPKALVGIITNPVNTTVAIAAEVLKKAGVYDKNRLFGVTTLDVIRAETFVAEAKGVDVASVKVNVIGGHSGVTILPLLSQIEGVNFSDEEVAALTKRIQNAGTEVVEAKAGGGSATLSMGQAAFRFGMSLIRGLQGEANVVECAYVDGGSEHAVFFAQPVLLGKNGVEKVLPYGEVSAFEANARDAMLDTLKGDIQLGVDFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: ROK1_DEBHA
Sequence: MDIFRILSRGASLKKSKDITTDYAVPSRKQFVNEKQKEENLKSVVDKEVDFFHTKKHTSHKETEKKNDEGEDEIEDEVPPLTISSDDDARKLRKLNKSKVSGEDIPLPIGSFEDLIGRYKLDKKLLSNLIDAGFTEPTPIQDEAIPISLEGRDLIACAPTGSGKTLAFLIPLVQTILQSNPNVKNYGIRGLIISPTNELAVQIFQELNTMTKGKKMKIGILSKQLANKINNKIINSSKYDILVSTPLRLIDSIKNETISLSKVEQLVIDETDKLFDQGFVEQTDEILSNCTNTKLRKSMFSATIPSGVEEMAQSIMKDPIRVIIGHKEAASNTIEQKLVFTGNEEGKLLAIRQMIQQGEFKPPIIIFLQSITRAKALFHELLYDRLNVDVIHAERTPKQRDEVIKRFKSGDIWVLITTDVIARGVDFKGVNLVINYDVPQSAQAYVHRIGRTGRGGKAGKAVTFFTKEDDKAVKPIINVMKQSGCESGYSGWLEDMHKLSKNEKKDVKKHEIKRKQISTVPKIMKQKRKQREEMIDASKRRKQESQSNTE
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase ROK1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LIPB_BUCBP
Sequence: MYKKNIKIRNLGLRRIQDVCSSMNDFTITRKISTPDEIWLVQHYPVFTIGVSGTKHDVLVSNNIPIIFSNRGGKITYHAPGQLIIYVLINLFRRKLTVRRLILLMQNIIISTLKSFSIDSYILNNFPGVYVNNKKICSLGLRIRNGCSFHGMALNINMDLLPFEYINPCGNSFKMTQVIDIKPNLCFKIIKLMLMHKIREIFS
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_STRS2
Sequence: MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSSAGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: VKT_NAJAT
Sequence: MSSGGLLLLLGLLTLWAELTPVSGRPRFCELAPSAGSCFAFVPSYYYNQYSNTCHSFTYSGCGGNANRFRTIDECNRTCVG
What is the function of this protein?
Serine protease inhibitor that inhibits chymotrypsin (Ki=25 nM) (PubMed:15698956, PubMed:14990218).  Also interacts with vasopressin V2 receptor (V2R/AVPR2) (PubMed:35122240).  Inhibits vasopressin binding human V2R in the nanomolar range (Ki=112 nM), and also moderately inhibits vasopressin-induced cAMP production (IC(50)=138 nM).  In vivo, intraperitoneal injection of this protein into rats increases diuresis by 2. 2-fold, without any loss of electrolytes (PubMed:35122240).
What are the official names of this protein?
Kunitz-type serine protease inhibitor NACI, Naja atra chymotrypsin inhibitor, ACI, NA-CI.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCP_STRPB
Sequence: MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKYIEVPTVFQKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPIRADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAKAGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_GLOVI
Sequence: MRITVLSGSDSPEREVSLVSGRAVQAALETLGHEVTMVDPGPDLPVRLLENPPDFVWIALHGDKGENGKLQGLLDWLGLPYNGSGVTASAIAMDKVVSKRLFVAEGIPTPAYRVAEAVPQVSECQAWLAALGSPVVVKPADGGSTVGVTIAREAGHLPEAVRLALQYSPQVLIEQYIPGQEITVALLDGLVLPAIEIVPQGRDFYDYEAKYAPGGSRHLIPPNLAADVLKASVDAAYRACRAVGSTGLVRADVRVDPEGRPWVLEVNTLPGMTATSLAPEAAQAAGIDFEQLIQRIIDRSLD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC2_STRP1
Sequence: MKLTLNRILFSGLALSILLTLTGCVGRDAHGNPKGMIWEFLGKPMSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEPINKRIKQANSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYTKGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMMIFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSSRKDVTPSQNMEQANLPKKIKSNRNAGKQRKR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 2, Foldase YidC 2, Membrane integrase YidC 2, Membrane protein YidC 2.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOLD_CENSY
Sequence: MDGKAVAAAVKERVKMAVAELKSGGTDPCLATVLVGDDPASGTYVRNKHAACAEVGITTQDHRLGPSTTEGDLLKLIAELNSDRSVHGILVQMPLPEGIREIKVVSAISPLKDVDGLTPLNAGLLTAGTATLIPCTPLGIMEMLDYYNIELEGKEVVLINRSRLVGIPLHHLFLGRNATVTTCHSRTKDIGSISRRADVIVTAVGNRDKFVLTPDMVKEGAVVIDVAISRSDRGLTGDADYAAVSEKASHITPVPGGVGPMTVAMLLKNTTTAASLVKSLER
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HV03_CARAU
Sequence: MRLWLHLVLLVATLEGVRSQVQLVESGGDVKKPGDSLRLSCKASGYTFSGYTMYWVRQAPGKGLEWVSRIYDDGSDVSYADTVKGRFTISRDNAKNLLYLQMSNLKPEDTGRYYCAR
What are the official names of this protein?
Ig heavy chain V region 3.
Protein: BCRA_BACLI
Sequence: MSTIIKTTDLTKMYGSQKSVDHLNINVKQGDIYGFLGRNGAGKTTTIRMLLGLIKPTSGQIEIFGENFFKNKKEILRRIGSIVEVPGFYANLTARENLLINAKIIGIHKKNAIDEVLEIVGLQHETKKLVGKFSLGMKQRLGIARALLHYPELLILDEPTNGLDPIGIKEMRRLIHSLAKERNITIFISSHILSEIEQLVDHVGIIHEGKLLEEIPFDHLKKRNRKYLEFQLSDQNKAVVLMEQHFDIHDYEVHQDGIIRVYSHLGQQGKLNKLFVENGIDVLKITMSEDSLEDYFVKLIGGGTIG
What is the function of this protein?
Part of the binding-protein-dependent transport system for bacitracin that confer resistance to this antibiotic.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Bacitracin transport ATP-binding protein BcrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: SULA_SALCH
Sequence: MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMHPVRAHALPRRQHSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.