PharMolix/UniProtQA huggingface dataset:
Protein: ISIA_SYNY3
Sequence: MQTYGNDTVQYEWWAGNARFADQSGLFIAAHVAQAALTAFWAGAFTLFEISRFDPTQAMGDQGLILLPHLATLGWGVGDGGQIVDTYPYFVIGSIHLIASAVLGAGALFHTLRAPADLSTLKGQGKKFHFTWENPQQLGIILGHHLLFLGAGALLLAGKAMYWGGLYDATTQTVRLVSQPTLDPLVIYGYQTHFASISSLEDLVGGHIFVGFLLIGGGIWHILVPPLGWAKKVLLFSGEAILSYSLGGIALAGFVAAYFCAVNTLAYPPEFYGPPLAIKLGIFPYFADTVELPMHAHTSRAWLANAHFFLAFFFLQGHLWHALRALGFDFKRVEQAFDSLQT
What is the function of this protein?
Functions as an antenna for photosystem I (PSI) under iron-limiting conditions, when phycobilisomes disappear.  In the (PSI)3(Isi3)18 complex most of the harvested energy is probably used by PSI; in other PSI-containing supercomplexes a large part of the energy will probably not be used for light harvesting, but rather is dissipated to protect the organism from light damage.
What are the official names of this protein?
Iron stress-induced chlorophyll-binding protein, CP43'.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. IsiA/Pcb subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CATD_PIG
Sequence: GPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSGKSSTYVKNGTTFAIHYGSGSLSGYLSSQDTVSVPCNSALSGVGGIKVERQTFGEATKQPGLTFIAAKFDGILGMAYPRISVNNVVPVFDNLMQQKLVDKDIFSFYLNRDPGAQPGGELMLGGIDSKYYKGSLDYHNVTRKAYWQIHMNQVAVGSSLTLCKGGCEAIVDTGTSLIVGQPEEVRELGKAIGAVPLIQGEYMIPCEKVPSLPDVTVTLGGKKYKLSSENYTLKVSQAGQTICLSGFMGMDIPPPGGPLWILGDVFIGRYYTVFDRDLNRVGLAEAA
What is the function of this protein?
Acid protease active in intracellular protein breakdown.  Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation.
What are the official names of this protein?
Cathepsin D.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Lysosome. Melanosome. Secreted, extracellular space.
Protein: NDHI_WEDTE
Sequence: MFPMVTEFMNYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CND3_SCHPO
Sequence: MSCIQIISSSQTSIAGHRKLCNKLFTLRTQEGFETDILRALNIILTVKKGNSNADRVLRFLVTFVNYLQQKDPEIDIVQPILKHILRGLDAKDKTVRYRCCQIIARVVNCVKEIDDDLYNTLKEKLLSRVLDRESIVRLEAVVALSRLQEDTGDEENDVRNILLFLLQNDPSSEVRRSVLLNIEVSNSTLPFILERARDVDAANRKCVYARVLPKIGDFRYLSIKKRVRILKWGLNDRDESVEKAAADMLAYQWIENADNNLLELLERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFPEQFWLELTAESSLLARTFNEICIEKNYTDLLDKMPEVVQLTYYIERQYVSLRDKSSYDESCFIIEQLLYIGLSQDMVDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFCSLLVEIITEVFEQGHSQNQTEEQGNSNAPELNKNDYEGEEITVSQKSPSPSLPPNELNEPEPDDMDGYKEAFNELRCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREKGLECLSLVCLLNADLAFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKFTEYEDAISSILFEALGEFENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQVLGYFFPVYAFGAHENQWRIATIFCDALLSLLEIYRDLDEDDVQLSIGHIAQQMLDWTDNEKLYERKTQTGDDYIALNHNVHLHLANMIFESLPNASEGKERKFMISLLGKLKIPTDLPSSDYQRTKRKLETYESHGFTMDSTSLSILAKFERMLLQNEEARSKFEETEEERLMENAEENEHAGAEAISGEIIPDTVEANMEDEEEVYVKQEEDL
What is the function of this protein?
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.  The condensin complex probably also plays a role during interphase.
What are the official names of this protein?
Condensin complex subunit 3, CAPG homolog, p100.
What is the protein family that this protein belongs to?
Belongs to the CND3 (condensin subunit 3) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Protein: OMH1_SCHPO
Sequence: MVRLPRKFKRVLLLVVLLTLVVFVRFKKQYIPTISVFEGSLIDNRDTLSYFNISNLEPSERSEWLPNKRVNAAFVTLARNEDLNDLLKSIRKLEKTFNHKYHYGWVFLNNEEFSDEFKEHVIEAVSGKCEFGLVPQEQWSIPEYIDQDKMHENWKKLQELGILYADKESYRHMCRFESGFFYRHPLVQKYEYYWRVEPSVDFFCDLDFDPFAYMKENNKAYAFTITVTEYSETIPSLWPSTKEFIKMHPNALHPNNALNFISNDDGETYNGCHFWTNFEIAKVDFWESEVYSKYFDYLDKSGNFFYERWGDAPVHSIAVSLFADRDNIHFFNEIGYWHPGSGHCPLDDATRAKCDCDPYESIDYNGWSCLDKFYTAFEMPFPENWSFYSH
What is the function of this protein?
Mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins.  Plays a major role in extending alpha-1,2-linked mannose in the O-glycan pathway.
What are the official names of this protein?
O-glycoside alpha-1,2-mannosyltransferase omh1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 15 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus.
Protein: SERC_WIGBR
Sequence: MKDIFNFGSGPSMLPKIVLKKIKRDLFNWKNTNVSVMEISHRNKNFLKVIENIKNDIKFLLSVSNDYNIILLQGGARAQFSGIPMNLTNNFSDLADYINTGYWGMYAAIEAKKYCSVNIIDVIEKKDKLSILPMKNWNISKNSVYLHYCPNETINGTAIYETPKFKNKIVVADFSSTILSRPIDVNKFDIIYASSQKNIGVSGMTIMIFKKNIFLKQNKFTPSILNYEIIYKNNSLFNTPPTFNWYVSGLVLKWLIDQGGVKKINNINKIKSKLIYDIIDKSKFYKNNIYDEYRSYMNIIFYLPNKKLNNLFLKLSKINGLLFLKGHRAVGGIRASMYNSMTIKGAKKLANFMKYFEKRYG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1021_STRP4
Sequence: MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLTGDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SPG_1021.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FTSB_BUCAI
Sequence: MKILKIFLLSLLFWLQYSLWFGKNGVLDFIKIYRRVTIEKKNNEYLDMRNNQIILEIENFNNHINKDKKKT
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly extracellular.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: GLGA_XANOM
Sequence: MLPALKKGGRPRDALGRFIRHHERLPVSLADTRGVLFVVSEMADFIKAGGLGDVAAALPRALRHRYDVRVLIPGYRAVLERAGKVEIVGRVLAHAALPACDIGRIVQSDGLPIYILLSRELFERDGSPYVSTSGSEFEDNAIRFATLSHAAADIAAGHAGLGWKPRLLHLNDWPCALAAGYVRWSGGTTPCLLTIHNLAYQGLVPYSMAGALGIPAERVAELEFYGQMSFLRGGIVNADHVNTVSVSYAKQITGPAQGCGLDRLLAGRAAKGALTGIVNGIDASWDPRTDEYLDSHFSVNQWQGRQDNAAQVRKAFGLRESTGPLFAVVSRLVHQKGLDLICEVAPQIVAAGGQIAVIGGGEPDIERQVAELTRRYPGQVGAFIGFEEGLARRMFAGADFLLMPSRFEPCGLSQMYAQRFGCLPIAHATGGLIDTVDDGVTGFLFQHASVEALRRCLERAFRTFRLPGLLAAMRRAAMLRPSGWDVAGNKYLSLYERTAAIAPALATVS
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RMD5A_HUMAN
Sequence: MDQCVTVERELEKVLHKFSGYGQLCERGLEELIDYTGGLKHEILQSHGQDAELSGTLSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDSDISSVGIDGCWQADSQRLLNEVMVEHFFRQGMLDVAEELCQESGLSVDPSQKEPFVELNRILEALKVRVLRPALEWAVSNREMLIAQNSSLEFKLHRLYFISLLMGGTTNQREALQYAKNFQPFALNHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACALLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCTGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTDNNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex (PubMed:29911972).  Catalytic activity of the complex is required for normal cell proliferation (PubMed:29911972).  The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (PubMed:29911972).
What are the official names of this protein?
E3 ubiquitin-protein transferase RMND5A, P44CTLH, Protein RMD5 homolog A.
Protein: RL6_ROSDO
Sequence: MSRIGKKPVDLPAGVSASVSGQTIEIKGPKGTRAFKATDDVTLTVEDNVVTVTPRGKSKRARQQWGMSRTMVANLVTGVSEGFKKELEIQGVGYRAAMTGNTLKLNLGLSHDVDYTPPAGVTVTAPKQTEIVVEGIDEQLVGQVAANIRQWRKPEPYKGKGIRYKGEFVFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: GSTF_SILVU
Sequence: MTIKVHGNPRSTATQRVLVALYEKHLEFEFVPIDMGAGGHKQPSYLALNPFGQVPALEDGEIKLFESRAITKYLAYTHDHQNEGTSLIHKEKHEMAAQLVWEEVEAHQFDPVASKLAWELVFKGIFGMQTDTTVVEENEAKLAKVLDVYEARLTESEYLGANDSFTLVDLHHLPLLGYLMGTQVKKLFEERAHVSAWCKKILARPSWEKTLALQKQA
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase, GST class-phi.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Phi family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC45_DICDI
Sequence: MVLTTDTKFSEIYDIIKGDSVQGESVLILVARDCDSIAACKILTEILKSDLIAYNIKAVSGYEDLENVNSTLLENEEIKSIIMINCGGNIDITNVFTNLNDQQVAYIIDSHRPYSINNITNESSVLIIDDGTYIEQDELQQLSDDSEEEEEELEEEEAEEDVVEDEAEEAEEAEEAEEAEEAEFDPENEDNPENDEDDGGSENIDENERKSKKKNKKDKKSKRKHRKKKKKKSEKLEKTYYGKSAAVSMYSLSTFLNKQNLDDLLWYAVLGLTDQFIHEKITLDSYEQQYKNFKELILNNYPTDGDDDQEERYRPGNDEDDYDENGDLKRHPSSMFLHGDKIIPSDDFRFMLYRHWNLYESLFNSRYVACKLRVWKAKGRFQLESLFAMMGIPLDQVKQKYNSMNVHYKKQLKQLLAINGPKFGLVNLYFNSFLKKYSNNSEISASDTVYAVTALMESDNLESDQSDQDIWEQNFWEAYDSISNKNIDLLKIGLKQSIQLQKEITRQVTSMIEKRSVILSGPFRYAFITESSDLKYFIHPLALTKLGLFMMDAFISMGKAKRPFLIGALNENKNSYLIVGISGSHSTDIQSNTFGEYFRKSAEYTDATFKYQSFDTSIVEVSKTDLHKFVEHLHGTMQTTQISK
What is the function of this protein?
Required for initiation of chromosomal DNA replication.
What are the official names of this protein?
Cell division control protein 45 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC45 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALDH_PSESP
Sequence: MSSRESASRRPDPLRVTIMQSPSAFSLTIGGHGVATSDYLPVLNPATRQPIGQCPVASEEHVEQARAAAGDAFAVWRQVPYGKRCEQLQALAGILEAHLDELAQLLTHEQGKPLADARGELAGAIAFCQCAGSLPLPEVVHEQSATRLSKTVREPLGVVVAIVPWNYPVSIAFVKPDRRVGCRKHADSQAGADHAADYLRIGELIRDALPAGVINVLAGNDDLGPWLTGHADVAKISFTGSSVTGRHVARSAAADLKRLTLELGGNDAAVVMADSLSDAVVERVFWSAFTNAGQICMATKRLYIHESIYEAFRDKLVAYAQNVVIGDGSQPGVTMGPLQNAKQFAKVMSLIDAVRQRGGRLIECGQMRGGDGYFLPITFVDLPDESAPEVVEEAFGPLLPLLKFRDVDEVIERVNAARTGWLAASGVVIGRSAHGLQQPSTRSVWSTTGCDHAVYSFGGMKASGYGAESGLEGLLEFTTQKTVIIQQQ
What is the function of this protein?
Involved in an alpha-terpineol oxidation system.
What are the official names of this protein?
Probable aldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: VEG_BACSU
Sequence: MAKTLSDIKRSLDGNLGKRLTLKANGGRRKTIERSGILAETYPSVFVIQLDQDENSFERVSYSYADILTETVELTFNDDAASSVAF
What is the function of this protein?
Stimulates biofilm formation via transcriptional activation of extracellular matrix genes.  Acts by repressing SinR activity, independently of the SinI, SlrA and SlrR pathways.  Could also be involved in the regulation of other genes during biofilm and spore formation.
What are the official names of this protein?
Protein Veg.
What are the subcellular locations of this protein?
Cytoplasm. Spore core. Note=During sporulation, accumulates in the forespore compartment but not in the mother cell.
Protein: ILVD2_PSET1
Sequence: MTSEKPRKYSQKIVDGSAQAPSRSMLRAVGFNDDDFKKSQVGIASTWSMVTPCNMHINTLAEEVGKGVDSAGAKSVIYNTITVSDGISMGTEGMKYSLVSREVICDSIEAVSAGMGHDGIIAIGGCDKNMPGCLMGLARLNRPSIFVYGGTILPGENHTDIVSVFEAVGSYAAGDIPITQLEHIEKTAIPGAGSCGGMYTANTLASAIEALGMSMPNSSAQNAISQNKKQDCIDAGKAIVYLLEHDIKPSDIMTKKAFENAITLIITLGGSTNAVLHLIAMADAVGVEVTLDDFVRIGDKTPVIADLRPSGQYLMSELIEIGGIQPLMKRLLDAGMLHGDCMTVTGKTMAENLADVADYPAGQNIILPFDKPIKKDSHLVILAGNLAPEGAVSKITGKEGLRFTGNAKVYDSEEQGFAAIIDGQVVAGDVVVIRYEGPKGGPGMREMLSPTSAIMGKGLGNDVALITDGRFSGGSRGFVVGHVTPEAYEGGAIALVENGDSITIDAQSREMTLNITDEEMASRKQRWQQPAPKYTRGLLAKYARTVSSASTGAVTDKPS
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 2, DAD 2.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TGB3_WCMVM
Sequence: MDFTTLIIIGVYLLVFIVYFAKINTSVCTISISGASIEISGCDNPTLFEILPKLRPFNHGLSLPSN
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata.  May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity).
What are the official names of this protein?
Movement protein TGBp3, 7 kDa protein, Triple gene block 3 protein, TGBp3.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp3 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: ST7L_CHICK
Sequence: MADGCGTGKEPPYPGAAAALRRWEQLRRRAAAPWARGLLAVAAGLGLFYAALRVPLRLRDGLAAVTVFLSTLTPKFYFALTVTSSFISGLIFVFEWWHFRKYGTSFIEQVSVSHLRPLIGGVENSPPAPAAFSAGENEANRQNMPECKMWRNPLNLFRGAEYSRYMWVTGKEPLTYYDMNLSAQDHQNFFTCDTDALRPSDTVMQKAWRERNPQARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERYFKQALKAGEMIYRKSQNCHSQSPQHEAQLRRDTNVLVYVKRRLAMCARKLGRIRESVKMMRDLMKEFPLLSMLNIHENLLEALLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKARAVSERFSPETAFKRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLVLPPEHILKRGDSEAVAYAFFHLQHWKRIEGALHLLHCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHEVSVYPQKELPFFIHFTAGLCSFSAMLALLTHQFPELMVVFAKAVLRVLWPVSAPSVLASG
What are the official names of this protein?
Suppressor of tumorigenicity 7 protein-like, Protein HELG.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PKSG_BACSU
Sequence: MVSAGIEAMNVFGGTAYLDVMELAKYRHLDTARFENLLMKEKAVALPYEDPVTFGVNAAKPIIDALSEAEKDRIELLITCSESGIDFGKSLSTYIHEYLGLNRNCRLFEVKQACYSGTAGFQMAVNFILSQTSPGAKALVIASDISRFLIAEGGDALSEDWSYAEPSAGAGAVAVLVGENPEVFQIDPGANGYYGYEVMDTCRPIPDSEAGDSDLSLMSYLDCCEQTFLEYQKRVPGANYQDTFQYLAYHTPFGGMVKGAHRTMMRKVAKVKTSGIETDFLTRVKPGLNYCQRVGNIMGAALFLALASTIDQGRFDTPKRIGCFSYGSGCCSEFYSGITTPQGQERQRTFGIEKHLDRRYQLSMEEYELLFKGSGMVRFGTRNVKLDFEMIPGIMQSTQEKPRLFLEEISEFHRKYRWIS
What is the function of this protein?
Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.  It catalyzes the aldol condensation between the acetyl group attached to the acyl-carrier-protein AcpK (Ac-AcpK) and a beta-ketothioester polyketide intermediate linked to one of the consecutive thiolation domains of PksL.
What are the official names of this protein?
Polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG, HMG synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_LIMF3
Sequence: MATLQFVLGSASFDHQQVMLDRLAAQYQQAPNDTYLYLVPNHVKFTTEVAVLKGLKKRLKQTGNYAQANVAVLSFSRLGWFLCKDDPDYQKPRLSNVGMAMVVAKIIRELKAESPDLLKMFRGESERQGFATEVTKQLVELQNANIQPADLAPDQETGIIKRALASQAGGGRASQSTVFTDKMTVLYEIYRRFEAAVTTHVTAPDRSAMLLNHLEAADLSTTHVYLDRFAGEFSAQEQLIVDALIQRAADTTVSLILDRDYRGRELPSQNNLYYRSAKQYQDLLNLATQQVGVDVLDPIVLNQPNQRRVSDALVGVEEWMEADARFALPDRLPAPTDQVGFFTAPTRVAELNRVATKIRQLVATGQYRYRDFLVVTRHLDGYQTMLEPIFSRHQIPVFNDNQRPMATSPLATFTAALFKVLKDYYQEADVMELLKTGLLVPETPEELQQEGRAKRNPNTFMTAVYRTENYCLKFGKGGRSWFDERPWRLEGEQPESDALKRQNAQINWVKNYIKDELAPALADLQTATTGRELATKFYQFLLDQGVRHQLYSWAHQAQESGQLTQLRDVQQIWQTFGTLLDEYVTILGDQVAPTEQPGQLVAEFADLMNAGFNAGRYAQIPSTLDQVLVSESGMIQDNQRKVLFIMGATDDVMPEVKASEGLLSDPDRELLKRGLNDDQFLPISGTDQINNEPFLNYLSMLSVTERLYMSAPLMSSDDSELTLSPYLKGLARHFNQWDDQNNAPTTDLPDRPNPRASEDDVWSFVAAPAVTMGNLIEVERLSKDTGRKLTSAWRDVARALTRYDEGLTGRLNDIRDGQYAKNEAVPLQPELAARLYTTNRQGQVTNQLTASISQLEKFYQNPYDYFLRYGLHLKKRDELEVSSDKSGTLNHDALAFFVQSVIDEPDLQLADLVKEEHQGRQAELIDQAFEQAMNQQEELRELAANNSRVNLQLQVAKQLITTMAKTLCLQATQTDAQPVAVEKAFGQADWTGESQAAELPALTFDLTGAGLGEGAKVSLRGRIDRLDELKLGEQTYQLVVDYKSYNKAFDLVDAYAGQALQMLAYLNALQAANPGKQLLGSLYLRLYVPTVDAGKEGTAEELKEHLYQGITINDDAVLAALDHGLGEKGATLLSIKKKSKKDTSRFKVSADDQFSAKAGSNLVSPTDLKRLMDHNAELIKEAAVQILQGQNEIRPYRRQVGTTAETGLAFSDFLDVSRFDQALDDYKEIELTDADVEAKFEQEEE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: JZT25_CHIGU
Sequence: MRALLIIAGLALFLVVCNASQVNEQRKLNEMLSVMFAVEEPQERDDCLGMFSSCNPDNDKCCEGRKCDRRDQWCKWNPW
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U16-theraphotoxin-Cg1a, U16-TRTX-Cg1a, Jingzhaotoxin-25, JZTX-25, Peptide F1-25.14.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 34 (Jztx-26) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSME1_MOUSE
Sequence: MATLRVHPEAQAKVDVFREDLCSKTENLLGSYFPKKISELDAFLKEPALNEANLSNLKAPLDIPVPDPVKEKEKEERKKQQEKEEKEEKKKGDEDDKGPPCGPVNCNEKIVVLLQRLKPEIKDVTEQLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTNLHTKLEGFHTQISKYFSERGDAVAKAAKQPHVGDYRQLVHELDEAEYQEIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKGMIY
What is the function of this protein?
Implicated in immunoproteasome assembly and required for efficient antigen processing.  The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
What are the official names of this protein?
Proteasome activator complex subunit 1, 11S regulator complex subunit alpha, REG-alpha, Activator of multicatalytic protease subunit 1, Proteasome activator 28 subunit alpha, PA28a, PA28alpha.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
Protein: RS12_FERNB
Sequence: MPTINQLVKHGREKVKEKSKSPALQGHPQKRGVCVRVSTMTPKKPNSALRKIAKVRLSNGIEVTAYIPGIGHNLQEHSIVLVRGGRVKDLPGVRYKIIRGALDAAGVENRRQSRSKYGAKRPKAGAAAGAKGKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MIAB_CLAM3
Sequence: MSTLAEHVRDTPPAAERPRTYEVRTYGCQMNVHDSERLTGSLEAAGYVSAEGAEADIVVINTCAVRENADNKLYGNLGHLAGVKRRHEGMQIAVGGCLAQKDRATVLEKAPWVDVVFGTHNMGALPTLLERARHNGEAQLEILESLETFPSTLPTKRDEIASGWVSISVGCNNTCTFCIVPALRGKEKDRRPGDILAEIQALVDDGAVEVTLLGQNVNSYGVEFGDRQAFGKLLRAAGAIEGLERIRFTSPHPAAFTDDVIDAMAETPAVMPQLHMPLQSGSDRVLKAMRRSYRSERFLGILDRVRTRIPDAAITTDIIVGFPGETEEDFQETLRVVEAARFSSAFTFQYSIRPGTPAATMEEQVPADVVKERYGRLTALQERISHEENQRVVGRTVEVLVSAHEGRKDGDTRRVTGRAQDGRLVHLDVPAGSGEPRPGDAVEVEITRAAPFHLIADSVDQAPLRIRRTRAGDAWERAQADSCGVPAPAAGTSAGGPPRVSLGLPSLRASTIASAGAVDGSAHPRHRA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.