PharMolix/UniProtQA huggingface dataset:
Protein: TUSA_BUCBP
Sequence: MTVDNNVLDLRKLRCPEPIMLLRKKIREIKNGTTLLILSDDPSTIREIPQYCKFMHHKLLKINTKDTIYKFWIQKTHKM
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H1_ANAPL
Sequence: MSETAPVAAPAVSAPGAKAAGKKPKKAAGGSKARKPAGPSVTELITKAVAASKERKGLSLAALKKALAAGGYDVEKNNSRIKLGLKSLVGKGTLVQTKGTGASGSFKLNKKPGETKEKATKKKPAAKPKKPAAKKPASAAKKPKKAAAVKKSPKKAKKPAAAATKKAAKSPKKAAKAGRPKKAAKSPAKAKAVKPKAAKPKAAKPKAAKAKKAAPKKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: UB2J2_MOUSE
Sequence: MSNNSNKRAPTTATQRLKQDYLRIKKDPVPYICAEPLPSNILEWHYVVRGPEMTPYEGGYYHGKLIFPREFPFKPPSIYMITPNGRFKCNTRLCLSITDFHPDTWNPAWSVSTILTGLLSFMVEKGPTLGSIETSDFTKKQLAAQSLVFNLKDKVFCELFPEVVEEIKQKQKAQDELSNRPQNLPLPDVVPDGELHRGQHGIQLLNGHAPAAGPNLAGLPQANRHHGLLGGALANLFVIVGFAAFAYTVKYVLRSIAQE
What is the function of this protein?
In case of infection by the murid herpesvirus 4, its association with the viral E3 ligase K3 mediates ubiquitination of host surface class I (MHC-I) H-2D(b)/H2-D1 and H-2K(b)/H2-K1 molecules before they exit the endoplasmic reticulum, leading to their degradation by the ERAD system, thus blocking the immune detection of virus-infected cells.  The complex formed with the murid herpesvirus 4 protein K3 mediates ubiquitination of lysine, as well as serine and threonine residues present in the cytoplasmic tail of surface class I molecules and promotes ubiquitination of hydroxylated serine or threonine residues via ester bonds instead of the classical isopeptide linkage.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 J2, Non-canonical ubiquitin-conjugating enzyme 2, NCUBE-2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: GATB_DINSH
Sequence: MLDLTYETPKPKVIAGAREDWELVIGLEVHAQVATNAKLFSGASTLFGAEPNSNVAFVDAGMPGMLPVINEECVAQAVRTGLGLKAAINLTSAFDRKNYFYPDLPQGYQISQLYHPIVGEGEVLVELGDGTARVVRIERIHLEQDAGKSIHDMDPHMSFVDLNRTGVALMEIVSRPDIRGPEEAAAYVSKLRQIMRYLGTCDGNMQNGNLRADVNVSVCRPGDYEKYQASQDFSHLGTRCEIKNMNSLRFIQQAIEYEARRQIAIIEDGGSVTQETRLYDPDKGETRSMRSKEEAHDYRYFPDPDLLPLEIEQAWVDDIAAALPELPDAKKARFITEFGLSDYDASVLTADTTNAAYFEAVAGEAGDGKLAANWVINELFGRLKKEDHDITESPVSPAQLAGIIKLIKADAISGKIAKDLFEIVYTEGGDPAEIVEARGMKQVTDTGAIEAAVDEIIAANPAQVAKAQENPKLAGWFVGQVMKATGGKANPKAVNQIVAAKLAQQ
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: VP5_IPNVN
Sequence: MAKALSNKQTNNLYSIQDEHKQGNRNLLEIHYASRDWTSKHPGRHNGETHPKTRDLVIQPRGLRIRKWHSCLFPWGTRLTDRCTLQMECEPDGAGVRPVAGDVAGPEESLQLREADLKEIRHPKLHTTGRSLCSERDAQRCHLRRQSV
What is the function of this protein?
VP5 is not required for viral replication in vivo and its absence does not alter the virulence characteristics of the virus or the establishment of persistent IPNV infection.
What are the official names of this protein?
Protein VP5.
What is the protein family that this protein belongs to?
Belongs to the avibirnavirus/aquabirnavirus VP5 protein family.
Protein: MIAB_SHESM
Sequence: MSKKLHIKTWGCQMNEYDSSKMADLLGEYQGYTLTEEAEEADILLLNTCSIREKAQEKVFHQLGRWKTLKDKNPDLIIGVGGCVASQEGKAIKDRAHCVDIIFGPQTLHRLPDMIEQVRRGEKAVIDVSFPEIEKFDRLPEPRAEGPTAFVSIMEGCSKYCSFCVVPYTRGEEVSRPSDDIILEIAQLAEQGVREVNLLGQNVNAYRGATHDGGICTFAELLRYVAAIDGIDRIRFTTSHPIEFTQDIIDVYEDTPELVSFLHLPVQSGSDRILTAMKRGHMAIEYKSIIRRLRKARPDIQISSDFIIGFPGETKEDFADTMKLIEDVAFDHSFSFIYSARPGTPAADLPDDVDMEEKKQRLAILQDRITQQAMRYSRHMMGTVQRILVEGPSVKNPMELRGRTENNRVVNFEGLPKHIGSFVDVEIVDVYTNSLRGKFIRGEDEMDLRRNLRPSDILAKHKQDDDLGVTQFKP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALP_FUSCU
Sequence: GSTSYIYDTSAGSGTYAYIVDTGIITSHNGFNWAANDIISKSYSNYGTVLDIFAPGTSVLSS
What is the function of this protein?
Serine protease.  May be involved in the invasion of grains and hydrolyzation of grain proteins.
What are the official names of this protein?
Alkaline proteinase, ALP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLO2_HAEDU
Sequence: MLKITAIPALQDNYIWAIQQGQEVMIVDPAQADPVFHFLAKNKLNLTTILITHYHQDHIGGIAGLQATYPDLTIYGSHEVAQYVNHIVQAGDHLHLLNSDVEVINSAGHTAQHISFLFAQQYLFCGDALFSAGCGRVFTGDYQAQFNTLQRFKTLPESTLVFPAHEYTLTNLKFAASVLPNNNDIREAQARAETLRAQQQPTLPSTIKQELRINPFLQADNLAEFITLRQQKDQY
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: SODM_XANCP
Sequence: MAYTLPQLPYAYDALEPNIDAQTMEIHHTKHHQTYINNVNAALEGTEYADLPVEELVSKLKSLPENLQGPVRNNGGGHANHSLFWTVMSPNGGGEPKGEVAKAIDKDIGGFEKFKEAFTKAALSRFGSGWAWLSVTPDKKVVVESTANQDSPLFEGNTPILGLDVWEHAYYLKYQNRRPDYIGAFYNVVNWDEVERRYHAAIA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: RR7_SOLBU
Sequence: MSRRGTAEKKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDITVKARRVGGSTHQVPIEIGSTQGKALAIRWLLAASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PIEZO_ARATH
Sequence: MASFLVGFLLPSLLLAAALINWSVISFLDLIAFLLVHYIAPEIGYRFQRRHWLLWPIFIFSFAVFLAQVVYLVIWAALGQDWDTPDTGWMRVIGFMILKSWRNPTVMYFLALQLLTSLVALADIYSSRFGFARWRDTWWSHFSGIFEHLGSHLRVASCLLLPAVQLAVGICNPSWVSLPFFIGSCAGLVDWSLTSNVSGLFRWWRVLYIYAGFNIVLLYLYQLPINFSDMIRWIASFIGLFRISLETEGPDICSGLFLVLFYIMLSYVRSDLEDMDFIMSTSENNLAERLLPPKYSFFIRESRAGVRHTNVLLRGAVFKTFSINFFTYGFPVSLFALSFWSFHFASLCAFGLLAYVGYIIYAFPSLFQLHRLNGLLLVFILLWAVSTYIFNVAFSFLNTKVGKFGLGMLVALGNLVNNSVFLYLSEESSRSSNERSYVEADEETKVLVVATIAWGLRKCSRAIMLALIFLIAMKPGFFHAVYVIFFLMYLLSHNINRKIRKSLILLCEVHFALLYILEIDLVSNSLKQEGSASREVLFQLGLLRSESSWDFLEIALLACFCAIHNHGFEVLFSFSAIVRHTPSPPIGFSILKAGLNKSVLLSVYSSPSSSYSQDNTTYERHIASFLSAIGQKFLSMYRSCGTYIAFITILISVYLVKPNYVSFGYIFLLLLWITGRQLFEETKRRLWFPLKAYAVLVFMFIYCLSSFVSLQLWLSGFIDLYFYLGYNSKAPLLDNVWESLAVLIVMQLYSYERRQSGHYIPGQSSLLHPGVFGFFERFLAWHGQKILFAALFYASLSPISVFGFVYLLGLVICTTFPKSSSIPSKSFLIYTGFLVSAEYLFQLWGMQAQMFPGQKYAELSFYLGLRVYEPGFWGIESGLRGKVLVVAACTLQYNVFRWLERTSGLTVIKGKYEEPCPLFVSAEDTTASVSSSNGENPSSTDHASISMKQGEATSNSWPFFSPRGNQGAGFLHPKTGGSESGSSRKFSFGHFWGSIKESHRWNRRRILALKKERFETQKNLLKIYLKFWIENMFNLYGLEINMIALLLASFALLNAISMVYIALLAACVLLRRRVIQKLWPVVVFLFASILAIEYVATWNSFLPSDQAPSETSVHCHDCWSIAALYFKFCRECWLGVRVDDPRTLISYFVVFMLACFKLRADHISSFSESSTYHQMKSQRKNSFVWRDLSFETKSMWTVLDYLRLYCYVHLLDVVLILILITGTLEYDILHLGYLAFALVFARMRLEILKKKNKIFRFLRVYNFVLIIFSLAYQSPFVGNFNDGKCETVDYIYEVIGFYKYDYGFRITARSALVEIIIFMLVSLQSYMFSSQEFDYVSRYLEAEQIGAIVREQEKKAARKTEQLQQIREAEEKKRQRNLQVEKMKSEMLNLRVQLHRMNSDSNFGVASPRTEGLRRRKSPYLIPDSGAASPEIDGVVHRKEEQPIDEDSQYPFEAHEFPVSTTPEALDSPEYSFGASPCEITEVQQDLDVMSMERERKQKSEGKENPLISAVQLIGDGVSQVQFIGNQAVNNLVNFLNISPENSDTNEQSSVDDEVYDEMESQKRKHTPFERSTSLQSDRSSDGTSFQIGRIFRHIWSRMQSNNDIVCYCCFIIAFLWNFSLLSMVYLAALFLYALCVHTGPTHIFWVIMLMYTEIYILLQYLYQIIIQHCGLSIDAPLLHELGFPTQRIKSSFVVSSLPLFLIYIFTLIQSSITVKDGDWVPSADFTSRRNARGSQKDLTRIRLSQRILDVFKKLRDSAKLVIRSIYRYWISLTRGAESPPYFVQVTMDVHMWPEDGIQPERVECRMNQLLRLVHNERCEKGNPDLCPYSSRVHVQSIERSTETPNEALVVLEVEYASPTNGCSSAEWYKSLTPASDVAKEIRKAQHSGLGEGTGFPYPILSVIGGGKRDTDLYAYIFGADLIVFFLVAIFYQSVIKNKSEFIDVYQLEDQFPFDFVIILMVIFFLIVVDRVIYLCSFATGKVVYYLFSLILFTYAVTEYAWSIYPTQQHAAGLALRIIFLAKAMSLALQAIQIRYGLPHKSTLYRQFLTSEVSRINYYGYRLYRALPFLYELRCVLDWSCTATSLTMYDWLKLEDVNASLYLVKCDTVLNRATHKHGEKQTKMTKCCNGICLFFILLCVIWAPMLMYSSGNPTNIANPIKDASVQIDLKTVGGKLTLYQTTLCERISGDNIDLGLDLGSQSFLPTYNKNDIQLICCQADASVLWLVPDTVVTRFIQSLDWDTDMDITFTWVLNRDRPKGKETVKYERSVDPLDLPKRSDIQMVLNGSMDGFRVHNLYPKFFRVTGSGDVRSFEDQTDEVSADILINHANFKWWWSFHNLKASENISACEGMDGPVAIIMSEETPPQGFLGDTLSKFSIWGLYITFVLAVGRFIRLQCSDLRMRIPYENLPSCDRLIAICEDLYAARAEGELGVEEVLYWTLVKIYRSPHMLLEYTKLDYDA
What is the function of this protein?
Pore-forming subunit of a mechanosensitive non-specific cation channel, that conducts both sodium and potassium ions.
What are the official names of this protein?
Piezo-type mechanosensitive ion channel homolog.
What is the protein family that this protein belongs to?
Belongs to the PIEZO (TC 1.A.75) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MIP_LEGPN
Sequence: MKMKLVTAAVMGLAMSTAMAATDATSLATDKDKLSYSIGADLGKNFKNQGIDVNPEAMAKGMQDAMSGAQLALTEQQMKDVLNKFQKDLMAKRTAEFNKKADENKVKGEAFLTENKNKPGVVVLPSGLQYKVINAGNGVKPGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQVSQVIPGWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGPIGPNETLIFKIHLISVKKSS
What is the function of this protein?
Essential virulence factor associated with macrophage infectivity.  Exhibits PPIase activity.
What are the official names of this protein?
Outer membrane protein MIP, Macrophage infectivity potentiator, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PYRH_HALHL
Sequence: MPHYRRILLKLSGEALLGDGQYGIAANTLDRIADELAEINAMGVEVAVVIGGGNIFRGAGLAASGMDRVTADHMGMLATVMNALAIQDALERRSVFCRVMSAIKINQVCEDYIRRRAVRHLEKGRVVIFAAGTGNPFFTTDSAASLRAVEVGAELLLKGTKVDGVYSSDPVRDPEAKRYQQLTYDEVLSKRLEVMDATAIVLCRDQAMRIMVFDITSPGTMVAAARGEPVGTVVDPGLPSAQEESS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COG8_HUMAN
Sequence: MATAATIPSVATATAAALGEVEDEGLLASLFRDRFPEAQWRERPDVGRYLRELSGSGLERLRREPERLAEERAQLLQQTRDLAFANYKTFIRGAECTERIHRLFGDVEASLGRLLDRLPSFQQSCRNFVKEAEEISSNRRMNSLTLNRHTEILEILEIPQLMDTCVRNSYYEEALELAAYVRRLERKYSSIPVIQGIVNEVRQSMQLMLSQLIQQLRTNIQLPACLRVIGYLRRMDVFTEAELRVKFLQARDAWLRSILTAIPNDDPYFHITKTIEASRVHLFDIITQYRAIFSDEDPLLPPAMGEHTVNESAIFHGWVLQKVSQFLQVLETDLYRGIGGHLDSLLGQCMYFGLSFSRVGADFRGQLAPVFQRVAISTFQKAIQETVEKFQEEMNSYMLISAPAILGTSNMPAAVPATQPGTLQPPMVLLDFPPLACFLNNILVAFNDLRLCCPVALAQDVTGALEDALAKVTKIILAFHRAEEAAFSSGEQELFVQFCTVFLEDLVPYLNRCLQVLFPPAQIAQTLGIPPTQLSKYGNLGHVNIGAIQEPLAFILPKRETLFTLDDQALGPELTAPAPEPPAEEPRLEPAGPACPEGGRAETQAEPPSVGP
What is the function of this protein?
Required for normal Golgi function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 8, COG complex subunit 8, Component of oligomeric Golgi complex 8.
What is the protein family that this protein belongs to?
Belongs to the COG8 family.
Protein: REX_LIMRD
Sequence: MANKKIPRATAKRLPIYFRYLNVLKDANKQRVSSTELSEAVQVDSATIRRDFSYFGELGKRGYGYDVESLLKFFKGILHQDSLVSVALVGVGSLGSALLNFNFHQDTNLRISAAFDTKPEYANTVKSGIPIYPSEDMVKQLKEQQIDVVILTVPGIKAQHVADQLVEAGVKGILNFTPVRLSVPKNVQVQNIDLTNELQTLIYFIKNYTEDSIK
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_RICFE
Sequence: MLPSIAKHAASHQINPLKKHGQNFIFDSSLCDKIVRASNLAENSRVLEIGPGTGGLTRSILQKNPASLTVIETDERCIPLLNEIKEYYPNLNIIKQDALKINLTDLGYDKVTIISNLPYHIGTELVIRWLKEARLITNMTLMLQKEVVERICAMPSTKAYGRLSVICQLITKVEKCFDVAPTAFYPPPKVYSAIVKLIPLENPPSIALINKVEQITKLAFAGRRKMIKSSLKNLVPNIH
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_BARBK
Sequence: MQHTSRDHLSYNFKTTAPHPPVEWKISDGLVEYPEALRYMQKRVENIYAKIAHEQVWLLEHPSLYTAGTSANKNDLLIPHVFPVYEAGRGGEFTYHGPGQRIAYIMLDLKRRKQDIRAFISALEQWIIQTLAQFNIKGERREDRIGVWVVRPDRPSIISGIPAEDKIAAIGIRVRKWISFHGISINVDTDLTHYSGIVPCGITNHGVTSLLDLGLPITIHDVDNALKKAFEQIFGPTIDVS
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QORL2_BOVIN
Sequence: MAAAWGRFLSRAWLCRTAWQGCGRNYRAALCAELKRPLVIEEVTPRPVQPHEVRVNVHFCGINFADILACQGQYQERHQLPFTPGMEFSGMVLETGTDVSTVKEGDRVIGLPGFSGMAEECITDHKNLWQIPEKVSLREAAALPVSYGTAIFALEHRACTQPGETVLVTAAAGATGLAVIDVATNILQAKVIAAAGSDEKCQLAMQSGAQSSVNYSRGSLKEAVGKLVGSGGVNVVIDMVGGDIFLEALRSLAYEGRIVVVGFAGGTIASVPANLLLLKNVSAMGLYWGRYRQQNFPVFSRSLSSALQYCQEGRIQPHIGEVFELEEVNDAFLHVTQRKSTGKVLLSLK
What are the official names of this protein?
Quinone oxidoreductase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Protein: TRUA_SALEP
Sequence: MSGQQSSPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPINVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKTVPDDFHARFSATARRYRYIIYNHRLRPAVLAKGVTHYYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLLEVGAHNQPESWIAELLAARDRTLAAATAKAEGLYLVAVDYPDRFDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: Y5222_VIBPA
Sequence: MSESVEQHWSVYLIRNNRNALYCGVTNDIERRFKQHQLGKGAKALKGKGPLVLEWSTSFDSKVTAMRAEYFIKQLTKSKKEQLVELKALIAVDDNQQVMFESCSQS
What are the official names of this protein?
UPF0213 protein VPA1222.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: MNME_ECOK1
Sequence: MSDNDTIVAQATPPGRGGVGILRISGLKAREVAETVLGKLPKPRYADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNNVIADLDAVRAEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVRNKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CJ053_MOUSE
Sequence: MPAQAVVTLRYGPYSAVGLSVEHRTYRLQGLQAVLAKDGHQIILEQIEDWNLVELVVNEETVFQCDIQELEFGGDGKLDPLCEEARIAVLNAF
What are the official names of this protein?
UPF0728 protein C10orf53 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0728 family.
Protein: RUVB_STAAN
Sequence: MNERMVDQSMHSEETDFELSLRPTRLRQYIGQNSIKSNLEVFIKAAKLRHEPLDHVLLFGPPGLGKTTLSNIIANEMEVNIRTVSGPSLERPGDLAAILSGLQPGDVLFIDEIHRLSSVVEEVLYPAMEDFFLDIIIGKGDEARSIRIDLPPFTLVGATTRAGSLTGPLRDRFGVHLRLEYYNESDLKEIIIRTAEVLGTGIDEESAIELAKRSRGTPRVANRLLKRVRDFQQVNEDEQIYIETTKHALGLLQVDQHGLDYIDHKMMNCIIKQYNGGPVGLDTIAVTIGEERITIEDVYEPFLIQKGFLERTPRGRKATPLAYEHFAKSNEERG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YECJ_ECOLI
Sequence: MSQPLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQLKNIDFTNHPAAADPVTMRAIQKAIALIELKFTPQGESH
What are the official names of this protein?
Uncharacterized protein YecJ.
Protein: DNJC5_DROME
Sequence: MSAPGMDKRKLSTSGDSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSNQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITGCCCCCCCCCCCNFCCGKFKPPVNESHDQYSHLNRPDGNREGNDMPTHLGQPPRLEDVDLDDVNLGAGGAPVTSQPREQAGGQPVFAMPPPSGAVGVNPFTGAPVAANENTSLNTTEQTTYTPDMVNQKY
What is the function of this protein?
May have an important role in presynaptic function.
What are the official names of this protein?
DnaJ homolog subfamily C member 5 homolog, Cysteine string protein.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: GCH42_BURCH
Sequence: MEKALHRISSMNAALPDISLTDAAPGRRPLEWVGMQGIDLPVVVAEPGCRRDVHARADVQVDLPAPQVKGIHMSRLYGLLDGLADGEALSPAGLQRMLRAMVDSHRDCETRSARVRLRFDLLARRTALVTEGLAGWKAYPVRLDATLAGDAFALRAQVTVVYSSTCPCSAALSRHWIEQAFLTAFGHEARVEPTAVAAWLKRHAMAATPHSQRSEAVVSVALPADGTTLGLLDLIDRVEQALGTPVQTAVKRADEQAFAVLNGGNLMFVEDAARRVQAALEDRHASPRVRVRHLESLHPHDAVAWAAPLREGADAC
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2 2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: DTD_BACAN
Sequence: MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MF14B_HUMAN
Sequence: MSVEPPPELEEKAASEPEAGAMPEKRAGAQAAGSTWLQGFGRPSVYHAAIVIFLEFFAWGLLTTPMLTVLHETFSQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRISPWWYFAMISVSGVFSVTFSVIFAYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYLSASYGDSLVVLVATVVALLDICFILVAVPESLPEKMRPVSWGAQISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIAAFIAMVGILSIVAQTAFLSILMRSLGNKNTVLLGLGFQMLQLAWYGFGSQAWMMWAAGTVAAMSSITFPAISALVSRNAESDQQGVAQGIITGIRGLCNGLGPALYGFIFYMFHVELTELGPKLNSNNVPLQGAVIPGPPFLFGACIVLMSFLVALFIPEYSKASGVQKHSNSSSGSLTNTPERGSDEDIEPLLQDSSIWELSSFEEPGNQCTEL
What are the official names of this protein?
Hippocampus abundant transcript-like protein 1, Major facilitator superfamily domain-containing 14B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.