PharMolix/UniProtQA huggingface dataset:
Protein: Y690_SODGM
Sequence: MFGKGGMGNLMKQAQQMQEKMQRMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEVDPSLLEDDKDMLEDLIAAAFNDAARRIAETQKEKMAAVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SG0690.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: VATB_CLOPE
Sequence: MLKEYRTVTEVVGPLMAVEGVEGVKYDELVEIEMQTGELRRGKVLEVNGDKAMVQLFEGSAGINLKNTKVRFLGRPLEIGVSEDMLGRVFDGMGRPKDNGPNIIPEKRLDINGEAINPVARNYPSEFIQTGISAIDGLNTLVRGQKLPVFSGSGLPHKELAAQIARQAKVLNSDSKFAVVFAAIGITFEEAEFFVDEFTKTGAIDRSVLFMNLASDPAIERIATPRMALTTAEYLAYEKGMHVLVIMTDITNYCEALREVSAARKEVPGRRGYPGYLYTDLSTLYERAGRLVGKEGSITQIPILTMPEDDKTHPIPDLTGYITEGQIILSRELYKKGIMPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFSAYAQGKQAKELAAILGESALSDVDKAYAKFAEAFENEYVSQGFTTNRTIEETLNLGWKLLKILPRTELKRIRDEYLEKYMPVGEDE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: PYRR_BACMK
Sequence: MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQSKHKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: HEM3_PSYIN
Sequence: MTAQKIRIATRHSPLAMWQANFIKSELLKYHPNLIVELLPMKTKGDIILDTPLAKVGGKGLFVKELEVAILEGRADIAVHSIKDVPVDFPEGLGLTTICKREDPHDAFVSNHYKQLDELPEGAIVGTCSLRRQCQILALRPDIIIKNLRGNVNTRLRKLDEGEYDAIILAAAGLMRLEMQHRITSLIAPEVSLPAVGQGAVGIECRLDDEQTITLLKPLEDPETRIRITAERAMNLKLQGGCQVPIGSFAILENEQLFLRGLVGSVDGKQIIRKEITGHQNDAQQLGITLAEQLLACGAEEILAEVYKNQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PHP_DROME
Sequence: MDRRALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPLKDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGITFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTNHNQSPQTVLFSPMNVISPQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIATSSALQAALSASGAIFQTAKPGTCSSSSPTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQGPPSLTPTTNPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKRKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLPVQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAPKSSEVNGTDRPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ
What is the function of this protein?
Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  Component of the PcG multiprotein PRC1 complex, a complex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-118', rendering chromatin heritably changed in its expressibility.  Plays a role in regulating the expression of other pair-rule genes such as eve, ftz, and H.
What are the official names of this protein?
Polyhomeotic-proximal chromatin protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: TX807_LYCSI
Sequence: MKLIIFTGLVPFAIVSLIEAQAENEKACLPQYQVCTDAPGNCCSNLVCDCYGRYKSGTRIGRNCFCLQKGVIYKREN
What are the official names of this protein?
U8-lycotoxin-Ls1t, Toxin-like structure LSTX-H7.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB_CHLL3
Sequence: MRIELLNTPVDAVELRIEDQIRPRRMEDFTGQQRLTDNLKVFISAARMRGDALDHVLLSGPPGLGKTTLAHIIAEEMGGSLKATSGPMLDKAGNLAGILTSLQKGDVLFIDEIHRMPPAVEEYLYSAMEDFRIDIMLDSGPSARAVQLKVEPFTLVGATTRSGLLTAPLRARFGISNRFDYYPPELLETILMRSSTILGIGIERDAASEIAGRSRGTPRIANRLLRRARDFAQVDGMEIISRPTAMKTLDSLEIDEEGLDEMDKKIMDAVVNRFSGGPVGVGSLAVSVGEEQDTIEEVYEPYLIQAGYLSRTPRGRVATQRALLRFSDGSSALRGTLFDGQEHV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: FAEA_ASPNG
Sequence: MKQFSAKYALILLATAGQALAASTQGISEDLYNRLVEMATISQAAYADLCNIPSTIIKGEKIYNAQTDINGWILRDDTSKEIITVFRGTGSDTNLQLDTNYTLTPFDTLPQCNDCEVHGGYYIGWISVQDQVESLVKQQASQYPDYALTVTGHSLGASMAALTAAQLSATYDNVRLYTFGEPRSGNQAFASYMNDAFQVSSPETTQYFRVTHSNDGIPNLPPADEGYAHGGVEYWSVDPYSAQNTFVCTGDEVQCCEAQGGQGVNDAHTTYFGMTSGACTW
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin.  Binds to cellulose.
What are the official names of this protein?
Feruloyl esterase A, Cinnamoyl esterase, FAE-III, Ferulic acid esterase A.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. FaeA family.
What are the subcellular locations of this protein?
Secreted.
Protein: PPNP_SHEB8
Sequence: MSLLEQVSVSKKANIYFDGRVASRSVFFADGSKQTLGVVQPGEYEFSTSQGEIMEVISGRFEVLLPETTTWQEFSEGTQFELAANVSFKIRNTAIAEYCCSYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: ZBT8A_BOVIN
Sequence: MEISSHQSHLLQQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKETSQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMTDVISVCKTFIKSSLDISEKEKDRYFSLSDKDANSNGIERSSFYSSGWQDESSSPRSHLSPDQGTGIISGKSWSKYNYHPASQRNTQQPLTKHEQRKDSIKKAKHLRLSQPSEMTHYKSSKREARTSDSSSHASQSEEQAQMNAEMDSTPVSYQYGQGSDVTSRSFPDDLPRMRFKCPYCTHVVKRKADLKRHLRCHTGERPYPCQACGKRFSRLDHLSSHFRTIHQACKLICRKCKRHVTGLTGQVVQEGTRRYRLCNECLAEVGIDSLPIDLEAEQHLMSPSDGDKDSRWHMGEDENRSYVEIVEDGSADLVIQQVDDSEEEEEKEIKPNIR
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 8A.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCME_LEGPC
Sequence: MNPVRRRKLFILLFALTILSAAAALVLYALRQNISLFYTPTQIVAGEAPVKHHIRVGGMVEANSIVRAKKGLDVQFKITDFENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHAIQVLAKHDANYMPPQVKSALADKVKQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: END3_ASPTN
Sequence: MSNKKIEQWEIERYWEIFASLSNGQPRLNNSQAASVLRNSRLRDEQLEKVWDLADVDGDGELDFEEFCVAMRLVFDLVNGELQSVPQHLPDWLVPESKAHLVQATRVLSTGSEQFERIEDEDDTPGLKDGFDWYMNPSDKAKYEEIYSANKNQRGEISFGSLQPLYDSLDVPDTDIRSAWNLVNPSASPEINKDATLAFLHILNYRHEGYRIPRTIPASLRASFENNKIDYQVDNARPAQRWGPNGDTETPTGRKAKFGDTYLSRLGVGGKASYTPKGTDFNNTIQDEEWEKVRLRRELAELEAKLDSAKKASEGRRDQPRNDGRPSWVLVKKEALQLLDYKERELRELREGTGRSKDGQDLERIREDIRTVGEQVDGLKSHLARRNEYLHDLRRQVEEEKLSR
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein end3, Cytoskeletal adapter protein sagA, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: COX3_ANTCE
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLIMWFHFNSTTLLMLGLTTNMLTMYQWWRDVIRESTFQGHHTPNVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NU4LC_TOBAC
Sequence: MILEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINFVTFSDFFDNRQLKGDIFSIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSNLLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL3_DEHM1
Sequence: MIQGIIGKKIGMTQIFQEDGKAQPVTLVEAGPCVVVQVKTEKQDGYEAVQLGYGKAKHITSAVKGQCRGFGEFKVLREVDVDDIAAVNVGDQITVSDFKDGEKIDASGVSRGRGFAGVVKRWHFAGGPKTHGQSDRHRAPGSISSTTTPGRIYKGKRMAGHMGNDAVTIRNLVVLKTDAEKNLLMVKGAIPGGKNTIILIKKTGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: BCAS3_MOUSE
Sequence: MNETMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGSPLTEEKEKIVWVRFENADLNDTSRNLEFHELHSTGNEPPLLVMIGYSDGMQVWGIPISGEAQELFSVRHGPVRAARILPAPQLGAQKCDNFAEKRPLLGVCKSIGSSGTTPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGGACGDNIQSYTATVLSAAKTLKSGLTMVGKVVTQLTGTLPSGVTEDDVALHCNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSSQCAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLTSQDSYNNFTNNNPGNPRLSPLPSLMVVTPLAQIKQPMTLGTITKRTGPYLFGAGCFSIKAPCKVKSPPQISPSKSMGGEFCVAAVFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHMIEPRPISTAPKISDDTPLEIMTSPRASWTLVRTPQWNELQPPFNANHPLLLAAEAVQYYQLLLAGSLPPGSPGPITRHGSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFHFKTIQTSGQTTVISTSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSDPVSMPGSSRAVSDRRGVSTVTDAASGTFDRSVTLLEVCGSWPEGFGLRHMSSMEHSEEGLRERLADAMAESPSRDVVGSGTELQREGSIETLSNSSGSTSGSIPRNFDGYRSPLPTNESQPLSLFPTGFP
What is the function of this protein?
Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes.  Stimulates histone acetyltransferase activity.  Binds to chromatin (By similarity).  Plays a role in angiogenesis.  Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge.  Promotes filipodia formation.  Plays a regulatory role in autophagic activity.  In complex with PHAF1, associates with the preautophagosomal structure during both non-selective and selective autophagy.  Probably binds phosphatidylinositol 3-phosphate (PtdIns3P) which would mediate the recruitment preautophagosomal structures (By similarity).
What are the official names of this protein?
BCAS3 microtubule associated cell migration factor, Breast carcinoma-amplified sequence 3 homolog, K20D4, Protein rudhira.
What is the protein family that this protein belongs to?
Belongs to the BCAS3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Preautophagosomal structure. Note=Associates with chromatin. Recruited to estrogen receptor-induced promoters in a PELP1-dependent manner (By similarity). Localizes in the cytoplasm in stationary cells. Translocates from the cytoplasm to the leading edge in motile cells. Colocalizes with microtubules and intermediate filaments in both stationary and motile cells. The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner (By similarity).
Protein: P64_BYVU
Sequence: MTTRFSTPANYYWGELFRRFFGGQEWKNLMSEAASVSRPRYSSDFRFSDGVILSRKTFGESTGESFVREFSLLLTFPKTYEVCKLCGVAMELALNGMNRLSDYNVSEFNIVDVKTVGCKFNIQSVTEFVKKINGNVAEPSLVEHCWSLSNSCGELINPKDTKRFVSLIFKGKDLAESTDEAIVSSSYLDYLSHCLNLYETCNLSSNSGKKSLYDEFLKHVIDYLENSDLEYRSPSDNPLVAGILYDMCFEYNTLKSTYLKNIESFDCFLSLYLPLLSEVFSMNWERPAPDVRLLFELDAAELLLKVPTINMHDSTFLYKNKLRYLESYFEDDSNELIKVKVDSLLTRDNPELKLAQRWVGFHCYYGVFRTAQTRKVKRDAEYKLPPALGEFVINMSGVEEFFEELQKKMPSISVRRRFCGSLSHEAFSVFKRFGVGFPPITRLNVPVKYSYLNVDYYRHVKRVGLTQDELTILSNIEFDVAEMCCEREVALQARRAQRGEKPFQGWKGTKNEISPHARSSIRVKKNNDSLLNILWKDVGARSQRRLNPLHRKH
What is the function of this protein?
Movement protein that is involved in local cell-cell movement via plamodesmata.  At least five viral proteins, CP, CPm, p6, p64 and Hsp70h are essential for cell-cell movement.  Also plays a role in virion formation.  Together with Hsp70h and CPm, encapsidates the 5'-terminal portion of the viral genome.
What are the official names of this protein?
64 kDa protein, p64.
What are the subcellular locations of this protein?
Virion. Note=Integral virion tail component. The N-terminus is exposed at the virion surface, whereas the C-terminus is embedded in the virion.
Protein: VE1_BPV4
Sequence: MDPKGTTVLDFIEEQAECSQSDSEQGSEENCSDISDLIDNAEYEQGNSAELFAQQQAFDFHKDICTTKRNLKRSLRNAFQCITSQSNTPASRSAPKRRLLDDSGYNEDISTEVVQVDENGGSEGYGSLTSQHLSGVCLNQGDNGGVDKENVDCTALLRAGSRRAAYLGVFKEKFTISFTALTRIFKNDKTCCRNWVGTVYRAREELLEASKTILQKCCDFILLLTHTCKYGFLALFLLEFKTAKSRETVQRLFEHILQVEKEDMLLEPPKLKSLPAATFWWKIQHSNNSFKWGTLPDWIARQTMISHQIADDEPFSLSVMVQWAYDHNYTEESTIAYHYAKLASEDSNAAAFLKCNNQVKHVKECAQMTRYYKTAEMTEMSMGQWIKKCIGEIEGVGDWKQICKFLKFQNVNFLSFMSALKDLLHRVPKRNCMVICGPPNTGKSMFVMSFMKALQGKVLSFVNSKSHFWLQPLRGAKVAVLDDATRATWTYFDTYLRNGLDGTPVSLDMKHRAPLQICFPPLVITTNVNVMQDPAYFYLHSRIVCFEFPNTFPLDEAGNPLLLIDELSWKSFFERLWTQLDLTDAEEDEDGEPRSPFRCCPRSVATSL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: URED_CUPMC
Sequence: MRHPDFPSQLAMTSAWHASLRLRFAARAGRTAMVERRHEGPLRVQKPLYPEGEICHGVVLHPPAGVAGGDRLDIDIAVASGAHAVLATPGATKWYKSLGRDAAQHVRIEVAAGGKLDWLPQENIVFDDARARITTDVVVAPGGSAIGWDAVVLGRQASGERWASGALWLDTRVGDPDRALWIEQSHFDGASPLRGAVAGMDGLHILGTLWAIGPGATQELAEALAEHLPYRADLRAGVTCLAGYGTATAQSMLLLRVLGSDMEAVRHLMIDAWTVLRQPMHGVPARPLRLWST
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINA_STRS7
Sequence: MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAFFAHRKQTARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDGVTYVVLPGPPSELKPMVKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKYQTDPTIAPYAKTGEVTLRLSTKADHQALANERLDQLELQLLSIRTIDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLVELQRHGVVSSFTAEQMAAQARCLTDSDIGIGLTGVAGPEELEEQPAGTVFIGLATKNKVESLKVVIGGRSRLDVRYIATLYAFNMVRKALLKSENLL
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: Y2443_LEGPL
Sequence: MLSWALIFFIIAIIAAAFGFGGIAVAAAGIAKILFFLFLVMFVIFLIMGLIGRRGPPPV
What are the official names of this protein?
UPF0391 membrane protein lpl2443.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y504_TROW8
Sequence: MSGHSKWATIKRKKAVNDAQRSKNFAKLIRLIEVAAKQGGPDLAGNPGLAEAVQKAKKNSVPNDNIDRAIKRGSGLTGEHINYVSLVYEVKAFDGVALLVECLTDNKNRCAAGIRSIVTRSGCSMVNPGSLAYNFKRKGIVVLQDRDANGNLLSEDLVLSAVLEAEVDDIVPTGDCGFEIIAEPSNLSAVCNALRDSGIQYRSVETVYVPNSTVSLPEQKYDRIIRMIEALEESDDVQGVYTNLSGKDLACE
What are the official names of this protein?
Probable transcriptional regulatory protein TW504.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_METIG
Sequence: MSLMDPLANALNHLTNCERVGKKVFYIKPASKLIGRVLKVMQDHGYIGEFEFIEDGRAGIFKVELIGKINKCGAIKPRYAVKKHEFEKFEKRYLPARDFGLLIVSTSQGIMTHYEAKEKGIGGRLISYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MURC_BURP0
Sequence: MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTERLEALGARVSIGHDAANIEGANAVVVSTAVRSDNPEVLAARRLRVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLTSAGANARLGTGDFIVAEADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCIDDANVRQIVPLISKPVVRYGFAADAQVRAENVEARDGRMHFTVRREGREPLPVVLNLPGLHNVQNALAAIAIATDLDVADAAIQQALAEFNGVGRRFQRYGEIAAAGGGAYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAPISTANGDALSRALRAAGKVEPVFVATVDEVPDALAKLARDGDVVITMGAGSIGGVPGKLAQDTQQKG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.