PharMolix/UniProtQA huggingface dataset:
Protein: LGT1_CLOPE
Sequence: MNPVAFSIGSFEVRWYGIIIALGILIAMTLVSINAKKKNLNFDVILDLFLWCFPFAIIGARAYYVLFELENYHSFWDMINIRQGGLAIHGGIIGAFLTAFIYCKVKKVDFLAYADIVAPAFILAQGIGRWGNFFNQEAHGGQVTSEFISKFPEFIQRGMYINGAYYHPTFLYESIWDIFVAILLMIILYNITDRYKGVVISAYISLYSLGRFFIEGLRTDSLYFMNIRVAQLVSLLGIIIGIVAIIIIVSRGKKKRKGIFIN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPF_SHEDO
Sequence: MIHFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLANRNFGVGFDQLLLVEPPYDPDLDFHYRIFNADGSEVEQCGNGARCFARFVRNKGLTQKNKIRVSTSSGKMTLRLERDGSVVVNMGVPVTDPSNIPFKAKKVEKTYLLQTPVQTFLCGAISMGNPHCVIEVDDIDTVAVDEIGALLTRHERFSKGVNVGFMQIINPGHIKLRVYERGAGETLACGTGACAAAAIGQLQDKLSRQVRVDLPGGTLHIDWDGEGKPLWMTGPAEHVYDGQIQL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_DESOH
Sequence: MKDIQKERDFRNMPIDKVGIKNLKYPIRVLDRKNGCQQTVGTINMYVDLPHESKGTHMSRFVEMLHILQPEISPKTFSVILDQMKKDLDAASAHMEVTFPYFIEKAAPVSGTPGFMEYTCKLMGTSRADGRVDLVSEVVVPISSVCPCSKEISDGGAHNQRGEVRLAIRSKKFVWIEDLIQLVEAAASCELYSVLKRVDEKWVTEKGYQNPKFVEDIVRDVAVALKNDTNITWFNISVENFESIHNHSAYATITCGRINP
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: BIOA_AQUAE
Sequence: MWELDPKTLEKWDKEYFWHPFTQMKVYREEENLIFERGEGVYLWDIYGRKYIDAISSLWCNVHGHNHPKLNNAVMKQLCKVAHTTTLGSSNVPAILLAKKLVEISPEGLNKVFYSEDGAEAVEIAIKMAYHYWKNKGVKGKNVFITLSEAYHGDTVGAVSVGGIELFHGTYKDLLFKTIKLPSPYLYCKEKYGELCPECTADLLKQLEDILKSREDIVAVIMEAGIQAAAGMLPFPPGFLKGVRELTKKYDTLMIVDEVATGFGRTGTMFYCEQEGVSPDFMCLGKGITGGYLPLAATLTTDEVFNAFLGEFGEAKHFYHGHTYTGNNLACSVALANLEVFEEERTLEKLQPKIKLLKERLQEFWELKHVGDVRQLGFMAGIELVKDKEKGEPFPYGERTGFKVAYKCREKGVFLRPLGDVMVLMMPLVIEEDEMNYVIDTLKWAIKELEKEV
What is the function of this protein?
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA).  It is the only aminotransferase known to utilize SAM as an amino donor.
What are the official names of this protein?
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, 7,8-diamino-pelargonic acid aminotransferase, DAPA AT, DAPA aminotransferase, 7,8-diaminononanoate synthase, DANS, Diaminopelargonic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRVP1_AUSSU
Sequence: SNKKDYRKEIVDKHNALRRSVKPTARNMLSMEVNSKAAQNAQRRXD
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein asurin-1.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: SIA4A_PANTR
Sequence: MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCTCTHCIGQRKLSAWFDERFNQTVQPLLTAQNALLEDDTYRWWLRLQREKKPNNLNDTIKELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISHTYTPVLVKIRVKQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHYWENNPSAGAFRKTGVHDADFESNVTATLAAINKIRIFKGR
What is the function of this protein?
A beta-galactoside alpha2-3 sialyltransferase involved in terminal sialylation of glycoproteins and glycolipids.  Catalyzes the transfer of sialic acid (N-acetyl-neuraminic acid; Neu5Ac) from the nucleotide sugar donor CMP-Neu5Ac onto acceptor Galbeta-(1->3)-GalNAc-terminated glycoconjugates through an alpha2-3 linkage.  Adds sialic acid to the core 1 O-glycan, Galbeta-(1->3)-GalNAc-O-Ser/Thr, which is a major structure of mucin-type O-glycans.  As part of a homeostatic mechanism that regulates CD8-positive T cell numbers, sialylates core 1 O-glycans of T cell glycoproteins, SPN/CD43 and PTPRC/CD45.  Prevents premature apoptosis of thymic CD8-positive T cells prior to peripheral emigration, whereas in the secondary lymphoid organs controls the survival of CD8-positive memory T cells generated following a successful immune response.  Transfers sialic acid to asialofetuin, presumably onto Galbeta-(1->3)-GalNAc-O-Ser.  Sialylates GM1a, GA1 and GD1b gangliosides to form GD1a, GM1b and GT1b, respectively.
What are the official names of this protein?
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1, Alpha 2,3-ST 1, Beta-galactoside alpha-2,3-sialyltransferase 1, Gal-NAc6S, Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase, Monosialoganglioside sialyltransferase, SIATFL, ST3Gal I, ST3GalI, ST3GalA.1, ST3O, Sialyltransferase 4A, SIAT4-A.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in medial and trans cisternae of Golgi (By similarity). Secreted into the body fluid.
Protein: AROC_STAA9
Sequence: MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIYSRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLDGKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLQQQIADRRQLNVEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: Y3252_MYCS2
Sequence: MVGKSVVLFVLAAVLEIGGAWLVWQGLREQRGWLWAGAGVIALGAYGFVAAFQPDANFGRVLAAYGGVFIAGSLLWGMIADGFRPDRWDVAGAAVALVGVGLIMYAPR
What are the official names of this protein?
UPF0060 membrane protein MSMEG_3252/MSMEI_3169.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LENG1_BOVIN
Sequence: MNILPKKSWHVRNKDNVARVRRDEARAREEEKERERRVLLAQQEARTEFLRKKARHQNWLPALEAAEAGAPGSSGPVDLFRELLEEGKAVTKGNKEYEEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPRQGGPASGPGPDERIKSRLDPLREMQKHLGKKRKHSGDSGGHSTKEKAAPEKQRPKGPPSLEQLRADRLRREAAERARAEALLARVGGTAAPEEQPEEVDERRRRYNSQFNPQLARRPRRQDPPVAP
What are the official names of this protein?
Leukocyte receptor cluster member 1 homolog.
Protein: CRL_VIBCH
Sequence: MSEMTKTPTHYRLLSTLKAMGPYLREGQCSERFYLFDCLASCVNDKKSPEKREFWGWWMELTQNEQEMSACYHIGRYTLAGDWVAEAIPESAQAEVNHTQAEFHKKLVKTLRERFEISVTVSTESAPFA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_LACPL
Sequence: MQCPHCHHNGSRVVDSRPTDDGRVIRRRRECENCGFRFTTFERVEATPLLVIKKNGAREEFNREKVLRGIIRSAEKRPVSMETMTGVVDDVENKVRSLGENEISSQVIGEYVMEQLADIDEISYIRFASVYRQFKDMHVFLNELQDMMERDKVKLAKPSAKTTHAPKRKKD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RPOZ_DESHY
Sequence: MKQPSLDILLSKVDSKYTLVLAAAKRARTLMEDPEFEVNYRGSKPVSLAFDEIAKGKYHFELTREGIK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: TPX2_MOUSE
Sequence: MSQVPTTYSFDAPTDFINFSSLDAEEDTENIDSWFDEKANLENKFLRQRGIGEPFQGKNSLRKAKLQQGFVTPLKAVDNTYHKETEKENLQKQSIPSNDCSSLDAKRAVSGNTPVQPQRRSIRLSAQKDLEQKEKNHVASVEMKAKRCVAPATDCPPQKRMKVSHKKKLEEEEEGSAPATSRKNERETLEKAKGKHTVPGVPPAREKVLKSTEEQEIEKRLRMQQEVVELRRKNEEFKKLALAGPGQPVKKSTSQVTKTVDFHFLTDERIKQHPKNQEEYKEVNFMSELRKHSSTPARGTRGCTIIKPFNLSKGKKRTFDEAASTYVPIAQQVEAFHKRTPNRYHLRNKKDESLLPSKSVNKIARDPQTPILQTKYRTRAVTCKSTAEQEAEELEKLQQYKFKARELDPRIFESGPILPKRAPVKPPTQPVGFDLEIEKRIHERESKKKTEDEQFEFHSRPCPTKILEDVVGVPEKKVIPATVPKSPVFALKNRIRVPIKDEEEEKPVVIKAQPVPHYGVPYKPHIAEARNVEVCPFSFDTRDKERQLQKEKKIKEMQKGEVPKFKALPVPHFDTINLPEKKVKNVTQAEPFSLETDKRGAYKAEMWKHQLEEEQKQQKDAACFKARPNTVIFQEPFVPKKEKKSLAENPSGSLVQEPFQLATERRAKERQELEKKMAEVEAWKLQQLEEVRQQEEEQQKEELARLRKELVHKANPIRKYAAVEVKSSELPLTVPVSPKFSTRFQ
What is the function of this protein?
Spindle assembly factor required for normal assembly of mitotic spindles.  Required for normal assembly of microtubules during apoptosis.  Required for chromatin and/or kinetochore dependent microtubule nucleation.  Mediates AURKA localization to spindle microtubules.  Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.  TPX2 is inactivated upon binding to importin-alpha.  At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation.
What are the official names of this protein?
Targeting protein for Xklp2.
What is the protein family that this protein belongs to?
Belongs to the TPX2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules.
Protein: RL21_ARTS2
Sequence: MVYAIVRAGGRQEKVSVGDFVTLNRVPGGAGSTIELPALLLVDGDKVTSAAADLAKVTVTAEILQDLRGPKIVIQKFKNKTGYKKRQGHRQELTKVKITGIK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PUR5_SALTI
Sequence: MTDKTSLSYKDAGVDIDAGNALVDRIKGVVKKTRRSEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDAIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTAASVINGIAEGCLQSGCALVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSRVAEGDVLIALGSSGPHSNGYSLVRKIIDVSGCDPQTTLLEGKPLADHLLEPTRIYVKSVLELIENIDVHAIAHLTGGGFWENIPRVLPENTQAVINESSWQWPAIFTWLRTAGNVSRHEMYRAFNCGVGMVIALSAPEADKALALLNEKGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HA12_MOUSE
Sequence: MGAMAPRTLLLLLAAALGPTQTRAGSHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARWIEQEGPEYWERETRRAKGNEQSFRVDLRTALRYYNQSAGGSHTLQWMAGCDVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAGAAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTLRCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPLGKEQKYTCHVEHEGLPEPLTLRWGKEEPPSSTKTNTVIIAVPVVLGAVVILGAVMAFVMKRRRNTGGKGGDYALAPGSQSSDMSLPDCKV
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
H-2 class I histocompatibility antigen, D-D alpha chain, H-2D(D).
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: FIMA_BORPT
Sequence: MQLPTISRTALKDVGSTAGGTVFDVKLTECPQALNGQQVGLFFESGGTVDYTSGNLFAYRADSQGVEQVPQTKADNVQANLDGSAIHLGRNKGAQAAQTFLVSQTAGSSTYGATLRYLACYIRSGAGSIVAGNLRSQVGFSVMYP
What are the official names of this protein?
Protein FimA.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: THIC_PSEPG
Sequence: MTKQEKAINLSESAQVDQQSVQPFPRSRKVYVEGSRPDIRVPMREISLDDTPTDFGGETNAPVLVYDTSGPYTDPNVIIDVRKGLADVRSAWIDARGDTERLDGLSSDFGQQRLNDAELAKLRFAHVRNPRRAKAGANVSQMHYARRGIITAEMEYVAIRENMKLQEARAAGLLKEQHAGHSFGANIPKEITPEFVRQEIARGRAIIPANINHPEVEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLIWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKESAKVAHFCSMCGPKFCSMKITQEVREYAAKIEAVDVTVEEGMREQAERFRQEGSQLYHKV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: TERL_BPSF5
Sequence: MSRKSYPNVNAANQYARDVVRGKIVACQFVIQACQRHLDDLMAEKSKSFRYRFDKDLAERVAKFIQLLPHTKGEWAFKRMPITLEPWQLFVICCAFGWVNKGSRLRRFREVYTEIPRKNGKSAISAGVALYCFACDNEFGAEVYSGATTEKQAWEVFRPARLMCKRTPMLTEAFGIEVNASNMNRPEDGARFEPLIGNPGDGSSPHCAVVDEYHEHATDALYTTMLTGMGARRQPLMWAITTAGYNIEGPCYDKRREVIEMLNGSVPNDELFGIIYTVDEGDDWTDPQVLEKANPNIGVSVYREFLLSQQQRAKNNARLANVFKTKHLNIWVSARSAYFNLVSWQSCEDKSLTLEQFEGQPCILAFDLARKLDMNSMARLYTREIDGKTHYYSVAPRFWVPYDTVYSVEKNEDRRTAERFQKWVEMGVLTVTDGAEVDYRYILEEAKAANKISPVSESPIDPFGATGLSHDLADEDLNPVTIVQNFANMSDPMKELEAAIESGRFHHDGNPIMTWCIGNVVGKNMPGNDDLVKPVKEQAENKIDGAVALIMTIGRAMLKEPDDFLSSLDPDDDLLIL
What are the official names of this protein?
Putative terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the phage terminase family.
Protein: AROC_PROMT
Sequence: MGSSFGKLFTISSFGESHGGGVGVIIDGCPPRLELDINEIQNDLNRRRPGQSKITTPRNESDEVEILSGLLGNKTLGTPIAMVVRNKDHRPKDYSEIKKTFRPSHADATYQKKYGIQASSGGGRASARETIGRVAAGSVAKQLLNKSAKTEILAWVKRIHDIEAEIHPSEVTFDEIEKNIVRCPNQSAADLMIQRVEAFGKEGDSCGGVIECVVRNPPIGIGMPVFDKLEADLAKALMSLPATKGFEVGSGFGGTYLKGSEHNDPFLPSDSNQLKTATNNSGGIQGGISNGEDIVLRVGFKPTATIRKSQKTIDEDGNAITLKATGRHDPCVLPRAVPMVEAMVALVLADHLLRQRGQCPD
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PRM2_MACNE
Sequence: MVRYRMRSLSERPHEVHGQQVHGQDQGHNGQEEQGLNPEHVEVYERTHRGHSHHRRRRCSRRRLHRIHRRRHRSCRRRRRRSCRHRRRHRRGCRTRRRRCRRH
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-2, Sperm histone P2, Sperm protamine P2.
What is the protein family that this protein belongs to?
Belongs to the protamine P2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y1972_BACCZ
Sequence: MSNAYEEYMRQMVIPMRQELVRSGFEELTTEEAVTEFMENTTGTTLVVVNSVCGCAAGLARPSAGQAVVRAEKQPDHLVTVFAGQDKDATAKMREYFGEIPPSSPSMALLKGKEVVHFIHRHEIEGATMDEIITNLEQAFEKNC
What are the official names of this protein?
UPF0403 protein BCE33L1972.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: RSMA_BRUME
Sequence: MSIDSLPPLREVIERHDLMPKKSLGQNFLFDLNLTSKIARQAGDLRDQPVIEVGPGPGGLTRALLAQGAYVTAIERDDRCLEALAEIAAHYPGRLRIIAGDALEQDFTALFPEGPKPRIVANLPYNVGTQLLLNWLLVEPWPPFYSSMTLMFQREVAERIVAKLDSDHYGRLGVLAGWRTQAKIAFDVPPQAFTPPPKVMSSVVHIVPRETPLPCRAEALGQITQAAFGQRRKMLRQSLKSIGGAALLEKTGIDGTRRAETLSVEEFVALANACLP
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDSA_STAEQ
Sequence: MKVRTLTAIIALLIFLPILLKGGLILMLFAFLLALIALKELLNMNMIKFLSIPGLISALALIIIMLPQDAGEWVQVIQLKGLIAMSFIVLSYTVLSKNRFSFMDAAFCLMSVAYVGIGFMYFYETRSEGLRYILFAFLIVWLTDTGAYIFGRLMGKHKLWPVISPNKTIEGFFGGILCSILVPLVMQMFVDLHMNIWLLLLVTIVLSMFGQLGDLVESGFKRHFGVKDSGRILPGHGGILDRFDSFMFVLPLLNILLIQT
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TM174_RAT
Sequence: MEQSSNRPEDFPLNVFSVTPYTPSTADIQVSDDDKAGATLLFSGIFLGLVGITFTVMGWIKYQGVSHFEWTQLLGPILLSVGVTFILISVCKFKMLSCQLCTDNEERVLDSDQTSGGQSFVFTGINQPITFHGATVVQYIPPPYGSQEPLGMNTTYLQPMMNPCGLVPSSGAVAATPSPPQYYTIYPQDNAAFVESEGFSPFVGAGHDRPSSDADQLEGTQMGEEERVCFSPPPYEEIYALPR
What is the function of this protein?
Regulator of plasma phosphate homeostasis.  Decreases serum inorganic phosphate (Pi) uptake by regulating the sodium-phosphate cotransporter SLC34A1 trafficking by PTH and FGF23 in the kidney.
What are the official names of this protein?
Transmembrane protein 174.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: UBX6_YEAST
Sequence: MYEMSGIDSLFHDRVVHDYSHTSEQVIVVYISSAAGDNSWLHQWFKPGNLSDEERENILWVRLVNGTKECLLFKSIFPSSSAPSINILQNGLLECSIQGNSLSREQDPWETFINGLQSVFKGQVTKRKLFSKSNEEYQRVKRMIQNDKLERKYVFQNTNDPQRKPQKWKQLTVTDNVSYKSQKGFLAQNYCTLQLKLPNGYTISNTFPPQTKLHKVRMWLDYNCYDDGTPYLFHRNIPRVTLTRNDELKSLQELDLLPRSTLILEPLEANNKTFDYMEQSSLLHKVYSGLTSFWAKEPEVDASSSRLGYQRLGTNVSNSANYSLQKLSSLDMVSDGGGGGGGDSMTPSAYTTPRMYPSNGTSQLRQNVSELNLSSNNSASNTKVRTLGYSNNNGNN
What is the function of this protein?
Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.
What are the official names of this protein?
UBX domain-containing protein 6.
Protein: DXR_CAMHC
Sequence: MVVLGSTGSIGTNSLEIARKFNIEVEALACAENVKKLNAQIAEFHPKFVYIKDEKLKSKVAHNKIFSGENGICEMLNRCESKTVINALVGFAGLIPSLKIQNSGKILCLSNKESLVVGGKFLDTSKIRAIDSEHFGLKFLLENSAKPAKMIITASGGAFYKTPIKDLSSKKAADALKHPNWNMGAKITIDSATMANKLFEMLEAFWLYGCKNLDALIEPSSSVHALIEFIDGSTAAHLSRTDMKLAIAHAILPNLKSEILKPVDLLSLNLKFEKIDIKKYPIFELKDEVLSNPDLGVIINAANEIAVFAFLQGKCGFLDISSTIFKAVEKFNDLTPENAEDLIKIDKIVRNFARSELRL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RS10_POLAQ
Sequence: MQNQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAVVKGPVPLPTRIERFDILRSPHVNKTSRDQLEIRTHLRLMDIVDPTEKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MTNN_HAEIN
Sequence: MKIGIVGAMAQEVEILKNLMADRTETRVASAVIFEGKINGKDVALLQSGIGKVAAAIGTTALLQLAKPDCVINTGSAGGVAKGLKVGDIVISDETRYHDADVTAFGYEKGQLPANPAAFLSDKKLADLAQEIAEKQGQSVKRGLICSGDSFINSEDKIAQIKADFPNVTGVEMEATAIAQVCYAFNVPFVVVRAISDGGDGKASMSFEEFLPLAAKQSSALVLGMIDRL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: RL4_SALTI
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.