PharMolix/UniProtQA huggingface dataset:
Protein: DYN3_ASHGO
Sequence: MSSGNIWKQLLEENSEQLDQSTTETYVVCCENEDSLNQFLQQCWQIDEGEKVTNLEPLGFFTKVVSRDEENLRLNVYYAKSPLDAQTLQFLGVFLRQMETSQIRWIFLLDWLLDDKRLWLRQLRNSWAALEEAQVAPFPGGAVVVVLNPSHVTQLERNTMVWNSRRLDLVHQTLRAACLNTGSALVTLDPNTAREDVMHICALLAGLPTSRPVAMLSLQSLFIPHGADSIGKICTIAPEFPVATVFDNDFVSSTFEAAIAPELTPGPRVPSDHPWLTEPTNPPSEATAWHFDLQGRLATLYRHLGDSNKAISVTQHRFHKPRSEDYAYEFELPSKHPTIRDLIRSAAADSPNDVADSIDGLMDGIVQRNVH
What is the function of this protein?
Component of the cytoplasmic dynein which acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast.  Probably required for normal progression of the cell cycle (By similarity).
What are the official names of this protein?
Cytoplasmic dynein intermediate light chain DYN3, Dynein protein 3.
What is the protein family that this protein belongs to?
Belongs to the dynein light intermediate chain DYN3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y2938_XANC8
Sequence: MIKWAIIFAIIGLIAGALGFGGMAGAAMGIAKFLFWAGIIIAIVLFVLGMTIAKKVT
What are the official names of this protein?
UPF0391 membrane protein XC_2938.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KLK3_MACFA
Sequence: MWVLVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASHGRAVCGGVLVHPQWVLTAAHCIRSHSVILLGRHNPYYPEDTGQVFQVSHSFPHPLYNMSLLKNRYLGPGDDSSHDLMLLRLSEPAEITDAVQVLDLPTWEPELGTTCYASGWGSIEPEEHLTPKKLQCVDLHIISNDVCAQVHSQKVTKFMLCAGSWMGGKSTCSGDSGGPLVCDGVLQGITSWGSQPCALPRRPSLYTKVVRYRKWIQDTIMANP
What is the function of this protein?
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
What are the official names of this protein?
Prostate-specific antigen, PSA, Kallikrein-3, Semenogelase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SIT1_ORYSJ
Sequence: MRRPELIMRSLPLILFLSLGSFHLAAAAVDDQFTFDGFAGVNLTLDGTAVVTPGGLLMLTNGTTLLKGHAFYPSPLRFFHEATSGGGSSTVRSFSTAFVFGIVSEYADLSSPGLAFVVAKSRDFSSALQSQYMGLANARNNGNASNHFLAVELDTIVNAEFGDMSDNHVGIDVDGLASAAADDAGYHDDRTGAFVNMSLLSRAAARVWVDFDARTSLVNVTMAPLELPKPTTPLLSAAVNLSAVIEDEAYVGFSSSTGVVASRHYVLAWSFKMDGPAPSLNVSKLPALPVTIARAPSNVLKILLPIASAALVSALAIAVLVIHRRRRRYAELKEEWEVAFGPHRFSYKDLFRATNGFSDERLLGFGGFGRVYKGVLLVSRVEIAVKKVSHESRQGMKEFIAEVVSIGQLRHRNLVQLLGYCRQKGELLLVYDYMPNGSLDKYLYAENSKILSWAQRFRIIKGIASSILYLHEDWEQVVLHRDIKASNVLLDAEMNCRLGDFGLARLYDRGTDPHTTHVVGTIGYLAPELGHTGRPSKASDIFAFGVFMLEVTCGRRPVLQDTNGGQLLLVDMVLEHWRQGTVTDAVDPRLQGDFAVEEASLVLKLCLLCSHPLPSARPGIRQVVQLLDGAMPLPELSQAHLSCNMLALMQNQMGNSCSVASSVAGNISDIPRAR
What is the function of this protein?
Lectin-domain containing receptor kinase involved in salt stress response (PubMed:24907341).  Acts as negative regulator of salt tolerance (PubMed:24907341).  Mediates salt sensitivity by phosphorylating and activating MPK3 and MPK6 (PubMed:24907341).  Promotes ethylene production and mediates salt-induced ethylene signaling (PubMed:24907341).  Promotes the accumulation of reactive oxygen species (ROS) under salt stress conditions (PubMed:24907341).  Its kinase activity is triggered by salt stress and is required for its function in salt stress response (PubMed:24907341).  Phosphorylates B'KAPPA, a B regulatory subunit of phosphatase 2A (PP2A) (PubMed:31221736).
What are the official names of this protein?
L-type lectin-domain containing receptor kinase SIT1, Protein SALT INTOLERANCE 1.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: YNC8_CAEEL
Sequence: MVKRIFVQGLDSYTTESTVKKYFEQFGTLYECILPPPPRYSVFDNGPDEEKISTRSSIRYEPVENDDVLDDELDVERYDVEKHGDFESYMKKIGEGEAFIKEPRKTSAGYAYITFVDSNGYSNCMKSDIHEIDRAKCTVEPAKDENDKKLKVESKRLFVSYFPLDRLTSKELKMNFGAYGKITDVEFVSDSEGPLHFCIITFADSRSVDVLLTKSIYIRDVLMFTRRAVLKESVKIAEHKIKEQEQQNLVQLPPNHTAYLTPSRPVTSVHASSSASSNHYDPSAAAGYAPLYHQPPESDPLSQCGYGPRKW
What are the official names of this protein?
Putative RNA-binding protein R05D3.8.
Protein: CH60_CLOB8
Sequence: MAKMLKFGEDARRSMQIGVDKLADTVKVTLGPKGRNVVLDKKFGAPLITNDGVSIAREIELEDPYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLKNVTAGANPILIRTGIKMAVDKAVEEIQKISKQVDGKEDIARVAAISAADEEVGKLIADAMEKVGNEGVITIEESKSMGTELDVVEGMQFDRGYVSPYMATDTEKMEAVLENPYILITDKKISNIQEILPVLEQIVQSGKKLLIIAEDIEGEAMATLVVNKLRGTFTCVAVKAPGFGDRRKEMLQDIATLTGGTVIAEELGRELKDVTIDMLGTADSVKVSKENTVIVNGKGDSNAIKERINQIKAQIEETSSEFDKEKLQERLAKLAGGVAVIKVGAATETELKEKKLRIEDALAATKAAVEEGIVAGGGTAYVNVINEVAKLTSDVADTQIGINIIVKSLEEPVRQIATNAGVEGSVIIEKVKNSEPGIGYDALHGEYINMIKGGIVDPTKVTRSALQNAASVASTFLTTEAAVADIPAKETPMPGAPGMGMDGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIE_SHIFL
Sequence: MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFSGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: DEN2B_HUMAN
Sequence: MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN
What is the function of this protein?
May block ERK2 activation stimulated by ABL1 (Probable).  May alter cell morphology and cell growth (Probable).
What are the official names of this protein?
DENN domain-containing protein 2B, HeLa tumor suppression 1, Suppression of tumorigenicity 5 protein.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm, cell cortex. Cell membrane. Recycling endosome. Note=Colocalizes with RAB13 and ITSN1 at cytoplasmic vesicles that are most likely recycling endosomes. Colocalizes with the cortical actin cytoskeleton.
Protein: RL36_CYAP4
Sequence: MKVRASVRRICEKCRVIRRKGRVMVICANPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RT10_DANRE
Sequence: MAASMANFRTLRVLSKIFHGHFTAASAVQHHTACPRLVHTVSVFSPPSPAITESEEPDTLYQRLSVQVKGHDRAVLDSYEFFATLAAKELGLSLEKVFEPPKHIDKLTLLKSRHIFKKHRVQYEMRTHYRCIQISRITGSSARVYLEYIQRNLPEGVAMEVTKTAMEKIPEHIQKPLWDDNKPEASG
What are the official names of this protein?
Probable 28S ribosomal protein S10, mitochondrial, MRP-S10, S10mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MGLA_FUSNN
Sequence: MENLKYVLEMENISKEFPGVKALDDVQLKLKPGTVHALMGENGAGKSTLMKCLFGIYEKNSGKILLDGVEVNFKSTKEALENGVSMVHQELNQVLQRNVLDNIWLGRYPMKGFFVDEKKMYNDTINIFKDLDIKVDPRKKVADLPIAERQMIEIAKAVSYKSKVIVMDEPTSSLTEKEVDHLFRIIKKLKESGVGIIYISHKMEEIKMISDEITILRDGKWISTNDVSKISTEQIISMMVGRDLTERFPKKDNKAKEMILEVKNLTALNQPSIQDVSFELYKGEILGIAGLVGSKRTEIVETIFGMRPKKHGEIILNGKTVKNKSPEDAIKNGFALVTEERRSTGIFSMLDVAFNSVISNLDRYKNKFRLLKNKDIEKDTKWIVDSMRVKTPSYSTKIGSLSGGNQQKVIIGRWLLTEPEVLMLDEPTRGIDVLAKYEIYQLMIDLAKKDKGIIMISSEMPELLGVTDRILVMSNGRVAGIVKTSETNQEEIMELSAKYL
What is the function of this protein?
Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Galactose/methyl galactoside import ATP-binding protein MglA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CH10_ALIF1
Sequence: MNIRPLHDRVIVERQEVESKSAGGIVLTGSAAEKSTRGTVLAVGKGRILENGTVQPLDVKVGDSVIFAEGYGTKSEKIDGKEVLIMSENDIMAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LV460_HUMAN
Sequence: MAWTPLLLLFPLLLHCTGSLSQPVLTQSSSASASLGSSVKLTCTLSSGHSSYIIAWHQQQPGKAPRYLMKLEGSGSYNKGSGVPDRFSGSSSGADRYLTISNLQFEDEADYYCETWDSNT
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 4-60.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: RL11_PECCP
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTESVEKGLPIPVVITVYSDRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKVTSAQVREIAETKAADMTGSDVDAMARSIAGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: ATPB_METFK
Sequence: MSQGKVVQCIGAVVDVEFPRDQMPKVYDALILDEDSPTVEAGLTLEVQQQLGDGVVRTIAMGSSDGLSRGMKVKNTGSQIQVPVGHGTLGRIMDVLGRPIDEAGPIEADEKRSIHQKAPTFEELSPSVDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVGMVFGQMNEPPGNRLRVALTGLTMAERFRDEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLTDPSPATTFLHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQIVGEEHYSVARAVQSTLQRYKELRDIIAILGMDELSPEDKLAVARARKIQRFLSQPFHVAEVFTGAPGKYVPLKDTIKGFKAIVNGEYDHLPEQAFYMVGSIEEAVEKAKTLN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KITH_PSET1
Sequence: MAQLYFYYSAMNAGKSTTLLQSAFNYQERGMEPVILTAAIDDRAGVGKVSSRIGLQADAHIFDENKDVFALIQSLNQDKKRHCVLVDECQFLSKEQVMQLTDVVDELGIPVLCYGLRNDFRGELFTGSQYLLAWADKLVELKTVCHCGRKANHVLRTDENGDAIADGNQVEIGGNNRYESVCRKHYKAALNMGR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAG_SALA4
Sequence: MSKVQSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKTGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPQTCVDLWVGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDVRAVNYLFKTPGGNLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMAESLNTKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENC_GEOSE
Sequence: MAINIEYVILRHLQMELKAPFTTSFGTFQRKELILVEVVDRDGVSGWGESVAFSAPWYSEETVKTNWHMLEDFLVPLALAEPIHHPEELSKRFSAIRQNNMAKAALEGAVWDLYAKRLGVPLSQALGGAKKDIEVGVSIGIQPTVADLLQVIERYVAQGYRRIKVKIKPSWDVDVIREVRRVFPDVPLMADANSAYTLVDADRLKALDEFGLLMIEQPLAADDLVDHARLQPLLQTPICLDESIRSYDDARKALDLGSCRIINIKIGRVGGLGEAKRIHDLCAERGAPVWCGGMLEAGVGRAHNIAITTLENFTLPGDTAASSHYWERDIITPEVEVHGGLIRVPDAPGIGYDVDRRQVERYTQFAKVFHRTATA
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (By similarity).  Also acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of N-succinyl-D/L-phenylalanine (PubMed:25875730).  Can catalyze the racemization of a broad range of N-acylamino acids, including N-acetyl-D-methionine, N-formyl-D/L-methionine, N-formyl-D/L-norleucine, N-formyl-D/L-aminobutyric acid, N-formyl-D/L-norvaline, N-formyl-D/L-homophenylalanine, N-carbamoyl-D-methionine and N-carbamoyl-D-norleucine (PubMed:25875730).  May be a bifunctional enzyme involved in menaquinone biosynthesis and in an irreversible pathway for the conversion of D- to L-amino acids, thereby facilitating the survival and/or growth of the organism (By similarity).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, N-acylamino acid racemase, NAAAR, N-succinylamino acid racemase, NSAAR, NSAR, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
Protein: PUR6_DROME
Sequence: MSTTTTASIEGYKLGKVIIEGKTKQVYDLPEQPGLCLLLSKDRITAGDGVKAHDLAGKAEISNTTNGQVFRLLNEAGIRTAYVKQCGAKAFIARKCQMIPIEWVTRRLATGSFLKRNVGVPEGYRFSPPKQETFFKDDANHDPQWSEEQIVSAKFELNGLVIGQDEVDIMRRTTLLVFEILERAWQTKNCALIDMKVEFGICDDGNIVLADIIDSDSWRLWPAGDKRLMVDKQVYRNLASVTASDLDTVKRNFIWVAEQLADIVPKKDHLVVILMGSASDISHSEKIATSCRSLGLNVELRVSSAHKGPEETLRIVREYESVMSNLIFVAVAGRSNGLGPVVSGSTNYPVINCPPVKSDNMQVDVWSSLNLPSGLGCATVLYPEAAALHAATILGLGNFMVWSKLRVKALNNFITLKKADKELRGVRNA
What is the function of this protein?
Bifunctional phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase catalyzing two reactions of the de novo purine biosynthetic pathway.
What are the official names of this protein?
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, PAICS, Protein adenosine-5.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
Protein: TKN_PHYBI
Sequence: QNPNRFIGLM
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Phyllomedusin.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRB_SULIY
Sequence: MRLRHVVSSLDLTRDDYFRIFELADKFSNVKKLNYLSGKVVSLAFFEPSTRTAQSFHTAAIKLGADVIGFASEESTSIAKGENLADTIRMLNNYSNCIVMRHKFDGAALFASEISDIPIINAGDGKHEHPTQALIDLYTIYKVFGEIDGRTFGLLGDLKYARTVNSLLRALTRFKPKKVFLISPSQLKVRREILDGLNYPVIETENPYDVIQDIDVLYVTRIQKERFVDEVEYEKVKESYVVDLKLVNMMKKDGIILHPLPRVTEIDRKVDKTTNAKYFYQASLAVPVRMALFYEVLGERKDD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL15_CUTAK
Sequence: MAIELHDLKPAPGAHKAKTRVGRGEGSKGKTAGRGTKGTGARKNVPEFFAGGQMPIHMQAPKLGGFHNPFRTEYQVVNLDKVEALFPKGGKITVDDLVSVGAVRDNELVKVLGTGELTVKVDLVVDAWSKSAQEKIEKAGGSVTKR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: GARL_SHIDS
Sequence: MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLAWGATFVAVGSDLGVFRSATQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: LEU1_CAUVN
Sequence: MTSVPAGAISKRDNVVVFDTTMRDGEQSPGASMSLEEKLELAKILEEMGVDVIEAGFPIASNGDFEAVRQIAELITESTVCGLARAAAGDIDRCAEAVRRAKRGRIHTFISTSPVHMKYKLQMEPDAVLEAITRSVSHARNLVGDVEWSAEDATRTERDFLKRCVEAAIKAGATTINLPDTVGYSYPSEYGELFRDVITSVPGADKAIFSAHCHNDLGLAVANSIAAIEGGARQVEVAINGIGERAGNAALEEIVMALRVRGDHLPYGTSVDPVHITRASRYVSAITGFPVQFNKAIVGKNAFAHESGIHQDGMLKNAETYEIMKPEDVGQGATNLVMGKHSGRHAFREKLKALGYELGQNALNDAFGRFKELADKKKHVFDDDIVALVDDALARGSEKIRVSRLRVVAGTDGQSAELTLDIDGVASTAEATGDGPVDAVFNAIHKIVPHSAALRLFQVHAVTEGTDAQAQVSVRLEEDGRIATGAAADTDTLTASAKAYVNALNNLFARKEKSRPEAAIASGF
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: NU1M_DROYA
Sequence: MEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALIMLSFIFLIGSYNMIYFFYYQIYMWFLIILFPMSLVWLTISLAETNRTPFDFAEGESELVSGFNVEYSSGGFALIFMAEYASILFMSMLFCVIFLGCDVFNLLFYVKLTFISFVFIWARGTLPRFRYDKLMYLAWKCFLSFSLNYLLFFIGFKILLFSFLLWIFFSKKLMEN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YSV6_CAEEL
Sequence: MGLVTSILGRREYRLLQNSVTKKHLCKFMGVEFDYNDLDEITEIRVGENIFDTFESYARFAMKDTMKSIFAECKAMKTCLARIEREKQTEASMNHKIRQCYITLRRLCQLYYKFYQDLEKLKIPEHAWNVPLVKKAEKSIVVLDHAIYKFKAKGNLDVKKFREEVSHQYNIIEEVLKQFKSMDEGEYVEMRMKEEMKTEEA
What are the official names of this protein?
Uncharacterized protein T19C3.6.
Protein: HYPE_CUPNH
Sequence: MSGTVKLGYQRPLNIKSGRIDMGHGAGGRAAAQLIQELFVAAFDNEWLRQGNDQAAFAMPAGARMVMATDAHVVSPLFFPGGDIGSLSVHGTINDVAMAGAKPLYLAASFILEEGFPLADLKRIVESMAGAAREAGVPIVTGDTKVVEQGKGDGVFITTTGVGVVPAGILIDGAGARPGDAILLSGTMGEHGVAILSKRESLEFDTEIRSDSAALHDLVAQMLAVVPGVRVLRDPTRGGLATTLNEISSQSGVGMVLDEAAIPVLPQVDAACELLGLDPLYVANEGKLVAICAAADADALLAAMRGHPLGREARRIGEVIEDGRHFVQMRTKFGGMRVVDWLSGEQLPRIC
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Along with HypF, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases.  HypE catalyzes the ATP-dependent dehydration of the carboxamido group attached to its C-terminal cysteine to a cyano group.
What are the official names of this protein?
Carbamoyl dehydratase HypE, Hydrogenase maturation factor HypE.
What is the protein family that this protein belongs to?
Belongs to the HypE family.
Protein: PUR7_STAS1
Sequence: MSLLYEGKAKRIFSTGTSDVLRVEYKDEVTAGNGAKKDFIEGKGRLNNQITSRIFNYLKAKGLNSHFIEQISETEQLVNSVEIIPLEVVVRNIAAGSITKRLGFEKGHTFETPLVEFFYKNDDLNDPLITEDHIKLLQIANDGEIEKLKEAATEINEVLVNLMDKMNLRLVDFKIEFGRTNEGEILLADEISPDTCRIWDKQSDTNFDKDVYREDTGSIIETYQTFLNKLEAL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.