PharMolix/UniProtQA huggingface dataset:
Protein: SYI_GLOC7
Sequence: MTEAKSYKDTVNLPQTKFDMRANAVKREPELQKFWAENQIYETLSENNPGDIFILHDGPPYANGSLHMGHALNKTLKDIINKYKLQRGYKARYVPGWDCHGLPIELKVLQSMKQKEREDLTPLKLRHKARDFALSTQKEQSESFQRFGVWGDWEHPYLTLTPDYEAAQIGVFGQMALKGYIYRGLKPVHWSPSSQTALAEAELEYPEGHTSRSVYAVFPITKASDTAKKVLTPYLKDLGVAIWTTTPWTLPGNLAVALNPDLTYAVVESGKPVCKHQYFIVAADLVDKLSATFETPLTVKATLKGEDLEHTTYRHPLFDRESEILIGGDYVTTESGTGLVHTAPGHGQEDYIVGQRYGLPVLSPVDEKGNFTSEAGQFAGLNVLKDANEAIIKELEEKGALLKEEPYQHKYPYDWRTKKPTIFRATEQWFASVEGFRDTALEAIKNVTWIPPQGENRITPMVADRSDWCISRQRSWGVPIPVFYDEETNEPLLNEETINHVQAIFAEKGSDAWWELSVEELLPQPYRNNGRKYRKGMDTMDVWFDSGSSWAAVAKQRPELSYPVDIYLEGSDQHRGWFQSSLLTSVATNGIAPYKMVLTHGFVLDEQGRKMSKSIGNIVDPNMIINGGKDQKKEPAYGADVLRLWVSSVDYSSDVPIGQNILKQLVDVRNKIRNTARFLLGNLHDFDPEKDTVAYEDLPELDRYMLHRITEVFTEVTEAFETFQFFRFFQVVQNFCVVDLSNFYLDIAKDRLYISDPNNLRRRSCQTVLKVALENLAKSIAPVLCHLAEDIWQFLPYKTPYKSVFEAGWVELESEWKRPELTPKWSKFRQIRDEVNKVMELARKDKMIGSSLDAKVLLYVSDKELREHLDSFNPSDSLSNNRVDELRYLFLASQVDLVDSPKTIGKANYKSESETLGVAIVKADGEKCDRCWNYSTHVGEFVDDPTLCERCNAALKGEF
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_COXBR
Sequence: MAEVRNYTFNFGPQHPAAHGVLRLIVEVDGEVIQRIDPHIGLLHRATEKLAESKPYNQTIGYMDRLDYVSMMANEHGYVLAIEKLLGIEPPIRAKYIRTMFDEITRILNHLLWLGAHALDVGAMTVFLYCFREREDLMDCYEAVSGARMHATYYRPGGVYRDLPDSMPKYKPSRWHNEKAVKKMNEAREGSLLDFIWDFTARFPNLIDEYESLLTDNRIWKQRTVGIGVVSAERALQLGFTGPMLRASGVEWDLRKKQPYAAYDRVDFDIPIGREGDCYDRYLVRIEEMRQSNRIIRQCVEWLRKNPGSVMIDDYKIVPPQREVMKRDMEALIHHFKLFTEGYIVPEGEAYAAVEQPKGEFGVYIVSDGANKPYRVKVRAASYPHLAAMNEMCRGHMIADLVAIISSIDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSMA_HALWD
Sequence: MTDATSGSDPDSTTPVDLTGEDFRDPDALRRRAGVSGDPNFDQHFLIDDRVLDRIPTYLLDSTDTTHILEIGAGTGALTDRLLAVGDTVTVIERDATLAAFLREEFAVMIDDGRLNIIEGDALEVTLPAFTTCISNLPYGISSEILFELLPADCPLIVMVQREFGERMAADPGTDAYGRLSVSAQHYATVEVVETVPPTAFAPEPAVDSALIRAEPRDPDYTVTDETFFLRFVKAVFTQRRKTVRNAIRNTAHISMLDTPDAVVNAADEALLSQRAGDLTPSEFAELATIAAEKGK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFUL_HORCR
Sequence: MSQTKNIIIFGGTGVIGKYITSAILASKESFDRVALFTSASTVSNKKEQLEEWKHQGLDIIVGDLTKDDDVLSAYRSFDTVVSAVGRNVIAEQINLIRLAEATPNITRFFPSEYGTDIEYNPQTSPHEKPHQLKLKVRKYIREEVRRLDVTYLVTGPYADLYLGNSNNAEYGSFDTKAKKATLLGSGEDPVSFTTMKDVGKLLVAALKHPEESKNKALKVNSFTATPNEILAEFEKQTGGQKWDVEYTSLAKLTELEKKAWEEGNPAATVYTLRRIWTEGGTLYKKRDNALIDAEETDSLAQAIAQVVDSQA
What is the function of this protein?
Reductase; part of the gene cluster that mediates the biosynthesis of enfumafungin, a glycosylated fernene-type triterpenoid with potent antifungal activity, mediated by its interaction with beta-1,3-glucan synthase and the fungal cell wall (PubMed:30051576).  The pathway begins with the terpene cyclase-glycosyl transferase fusion protein that most likely uses 2,3-oxidosqualene as substrate and catalyzes glycosylation immediately after cyclization (Probable).  The fernene glycoside then could be processed by the desaturase efuI which catalyzes isomerization of a double bond established by efuA to form the core structure (Probable).  The latter would then undergo a series of hydroxylations in unknown order at C-2, C-19, C-23 and C-25, which would be catalyzed by two of the three cytochrome P450 monooxygenases efuB, efuG or efuH (Probable).  The hydroxy-group at C-25 becomes oxidized by the dehydrogenase efuE to enable a spontaneous, non-enzymatic hemiacetal formation with C-23 (Probable).  After hydroxylation at C-2, acetylation by the acetyltransferase efuC takes place (Probable).  The final steps in enfumafungin biosynthesis require expansion of the 5-membered ring by lactonization via a Baeyer-Villiger reaction mediated by one of the BGC's cytochrome P450 monooxygenases (efuB, efuG or efuH) followed by ring cleavage (Probable).  This type of reaction would establish a double bond between C-20 and C-21 which could be reduced by the reductase efuL to form the final product (Probable).
What are the official names of this protein?
Reductase efuL, Enfumafungin biosynthesis cluster protein L.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SRP19_HALMA
Sequence: MVENVIWPAALDANRSRSDGRRVSLDLAVENPTVDEIAKAVQQVGYDAVIERDKTYPREYEGRGRVVVKDADDATKSDLLGAVAAYMQALRE
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DS1P1_YEAST
Sequence: MVDGLNTSNIRKRARTLSNPNDFQEPNYLLDPGNHPSDHFRTRMSKFRFNIREKLLVFTNNQSFTLSRWQKKYRSAFNDLYFTYTSLMGSHTFYVLCLPMPVWFGYFETTKDMVYILGYSIYLSGFFKDYWCLPRPRAPPLHRITLSEYTTKEYGAPSSHTANATGVSLLFLYNIWRMQESSVMVQLLLSCVVLFYYMTLVFGRIYCGMHGILDLVSGGLIGIVCFIVRMYFKYRFPGLRIEEHWWFPLFSVGWGLLLLFKHVKPVDECPCFQDSVAFMGVVSGIECCDWLGKVFGVTLVYNLEPNCGWRLTLARLLVGLPCVVIWKYVISKPMIYTLLIKVFHLKDDRNVAARKRLEATHKEGASKYECPLYIGEPKIDILGRFIIYAGVPFTVVMCSPVLFSLLNIA
What is the function of this protein?
Dihydrosphingosine 1-phosphate phosphatase required for efficient ceramide synthesis from exogenous sphingoid bases (PubMed:10477278, PubMed:10563329, PubMed:10856228, PubMed:11278643, PubMed:11967828, PubMed:12493772, PubMed:12684378, PubMed:12786943, PubMed:9195906, PubMed:9353337, PubMed:9419344, PubMed:25345524).  Involved in endocytosis and calcium-mediated signaling (PubMed:10856228, PubMed:11278643).
What are the official names of this protein?
Dihydrosphingosine 1-phosphate phosphatase LCB3, Long-chain base protein 3, Sphingolipid resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the type 2 lipid phosphate phosphatase family.
Protein: RCNR_SALAR
Sequence: MSHTIRDKQKLKARTSKIQGQVIALKKMLDEPHECAAVLQQIAAIRGAVNGLMREVIKGHLTEHIVHQGDEARREEDLDVILKVLDSYIK
What is the function of this protein?
Repressor of rcnA expression.  Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt.  In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity).
What are the official names of this protein?
Transcriptional repressor RcnR.
What is the protein family that this protein belongs to?
Belongs to the FrmR/RcnR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR3_THAPS
Sequence: MGQKTHPLGFRLGITQEHRSAWYADFKHYSTLLEEDDKIRTYLNKLAKLASISDIHINRNGLGDQIELNIETGRPGILVGDNGSGIKTLATNIKKFIPNNRQITINVVEVENVNANASLIADLVVQQLEDRVAFRRAIREALQCLQDNQVNGIKVEVSGRLNGAEMARSEWIREGRVPLQTLRADIDYATKEANTIYGVLGVKVWLFKNEILKK
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COFG_METS3
Sequence: MNKASKYRENNLITYSKNIFIPLTEICKNDCGYCNFKKTPDDPSAIILKTKEEVLASLKEAERYGCSEALFTFGEDADEEESVQQKLAEFGYENIVDYVFDICKMTLEETSLLPHTNGGNFSYESLKKLKEVNASMGMMLESTSVRLMNTVAHNKSPGKNPEIRLKTISNAGKLKIPYTTGILIGIGETKEEIADSLLAIRDLYDKYGHIQEVIIQNFTTSPGIEMENWEEPTFLDMVRTVIAGKLLFRDTDVSIQVPPNLNHDTAQIFLLCGADDWGGVSPVSPDYVNPTSPWPTLDELNRLTQDAGFELIERMCVYEKYVNDKWLNETLLEKIANLS
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: NU5C_HELAN
Sequence: MEQTYQYAWIIPFLPLPVPMLIGLGLLLFPTATKSLRRMWAFQSVLLLSIVMIFSLNLSIQQINSSSVYQYVWSWIINNDFSLEFGYLIDPLTSIMSILITTVGIMVLIYSDNYMSHDHGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPVAAKACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFQIFNNLISNNEVNSVFVTLCAVLLFAGAIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLMPLFIVIPHIMNFISFIGIITVFFGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSVIHSMETLVGYCPKKSQNMVLMGGLKKHVPITKNSFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIAWSTAGFTAFYMCRIYLLTFEGHLNVHFQNYSGKRNTPLYLISLWGKEGSKISNKNLNFCLVTLLKMNKNGRPSFFSNKVYKMDENGRNLIQPFLSIPNFSNTKTSLYPYESDNTMLFPILILILFTLFVGFLGIPFNQDVDILSKWLTPSINLLHQSSNNSIDWYEFCKDAVFSVSIACFGIYIAFFLYKPVYSSFQNLDLINSVVKMGPKRIFSDKIKNAIYDWSYNRGYIDAFYGTFFTAGVRKLAEFTHFFDRRIIDGIPNGVGFMSFFVAEVIKSVGGGRISSYLFFYFSYVSIFLLIYYFLNL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LST1_MACMU
Sequence: MIHVYTSTGAWGWAGSCCWLWSFCPPACIGCIEEHLLSWPQVQGSSEQEIHYASLQRLPVSSSEGPDLRDRDKRGTKEDPRADYACIAENKPT
What is the function of this protein?
Possible role in modulating immune responses.  Has an inhibitory effect on lymphocyte proliferation.  Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation (By similarity).
What are the official names of this protein?
Leukocyte-specific transcript 1 protein.
What is the protein family that this protein belongs to?
Belongs to the LST1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single- pass membrane protein. Endomembrane system; Single-pass membrane protein. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.
Protein: ZN445_MOUSE
Sequence: MPPGRWHAARSAQVSREQGCLRMVKEEEEDGYISMQTARPQTLNRPGQELFRQLFRQLRYHESSGPLETLSRLQELCRWWMRPDVLSKAQMLELLVLEQFLSILPGELRTWVQLHCPESGAEVVALLEELQRDLDGTPLKDPCLTQNPDVHWIGTSALQPAQIWSPASHLKNSSALEDHLETSHGIGICDVLAEQTDSPAVSVPDYFQLEEGIEYQEALTFQDVEVTFSQEEWGCLNSAQRNLYRDVILENYGNVVSVVGSSPKPALISWLEARKPWGVNICTVQLKRDADAAPEGGKLQIKPNKFILKQKPSEYIEACVKTSVSPETSVSEETGLKESFKQKSRLQTSCGDSIQMKEMKEGADISQRTGRESEVLRNNDILELKHVKCVSVSRKRLSFKHGYDRNFRKSSHHYNNKYGEGLRGTGEGFGVYQNTGLKENGKDRYGETSRKSWHAHPEHRQPSYSEEGLFQCRVCGKAFKWRSNRIRHEKIHTGVKPYQCSLCEKAFQRLSSYRLHQKTHSKQKRGSSKYKNALTCSLDVSHHLTDRDERKHLHCNQCGKNFSCKSYAIEHQRIHTQEKPYKCTRCRKTFRWKSNFSRHMKLHHKEVYKQEKRQEDFKQSYRQSQVISTVEKTFPCQNCGKTFTQKKSLIEHQRIHTGEKPYQCSGCGETFTYRSSYIIHMKRTQHAIKIKPEHGCLTFSQGAVFPIPRGSHNTEGSNKCKYCGKAFHNRSFLLIHERVHTREKPYQCRECEKAFRWSSNLYRHQRKHFLHKRYKYRESKETSNLQSKILIDQKPFWCQECGKTFTRKRSLLDHKGIHSGERRFKCNLCEKSFDRNYRLVNHQRIHTTEQPQWRDKDFVGIHARSVDQRKHSNTLQSEYGLHSDKPGLSYCQDVRLNIQELSGKLRKECDNPSDESSKSIAFQNVPTKKKACHKCSTCGKTFKKHSHLISHKRCHTKERPFKCIVCGKTFRWSSNLTRHMKNHVRN
What is the function of this protein?
Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation.  Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs) (PubMed:30602440).  Acts together with ZFP57, but ZFP57 plays the predominant role in imprinting maintenance.  In contrast, ZNF445 seems to be the major factor in human early embryonic imprinting maintenance (PubMed:30602440).
What are the official names of this protein?
Zinc finger protein 445.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Binds various differentially methylated regions (DMR).
Protein: PURA_STRP6
Sequence: MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRAHVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERLRINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLSGLDAVKICVAYDLDGERIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPENARNYVRRIGELVGVRISTFSVGPGREQTNILESVWASI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_METM5
Sequence: MSDENLLTTLDTYLASGIHIGTQQKTEDMRRFIYRVRADGLYVLDVRKTDERLRLAAKFLSNYEPEDIMAVTRRVYSVGPLKEFGKVTGINTVAGRFVPGTLTNPSAKKFAEPEVLFLSDPRVDKQALKEAIEIGIPVIGMCDTEHLTSHIDFIIPTNNKGRKSVSLMYYLIAREYMKNRGLIGEEVPFSYDQFLEKAMNVKVKMNPSNRQRGRFQRRRR
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RTL5_HUMAN
Sequence: MSEASGNLNSLRMANVALREELNALRGENANLGLQLGRALAEVNSLRGNVSSYIRWPVPIVPVLAEENLEFALSEIEVIPGGELPFLCRPPPRAEPDCISDDLLINVIQDRSTPDGPADPPLLPIPPPPALPPPASKEPPPQPPLAPLERPEIEPFSGDPVYLAEFLMQLETFIADHEVHFPGGAERVAFLISFFTGEAKDWAISVTQEGSPLHANFPRFLDEIRKEFCGPIPPRVAKKAIRKLKQGHCTLGSYADAFQFLAQFLSWDDCRLQNQFLKGLSEFFRKELLWSTEMADLDELILECVEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENFLGASPPIIQPSRRRNQNRVPLLEGLPGTNSPFYSSPQLIRRTGRLGQRQVRRRPPVLFRLTPRQGGHRAARGRIRV
What are the official names of this protein?
Retrotransposon Gag-like protein 5, Retrotransposon gag domain-containing protein 4.
Protein: PYRR_LIMF3
Sequence: MAHEIVDGSSMQRALTRITYEIIEQNKGVDNLVFVGIKTRGVYLAQRLAKRMEQLEGVKVPVGSLDITLYRDDRHQPDHHVEPTVNATDVDVDINDKHVILVDDVLYTGRTVRAALDALMDLGRPKRISLAVLVDRGHRELPIRPDFVGKNIPTSNSETVHVAVEEYDGHEDISLENRK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: RL24_CHLPB
Sequence: MKTGIKQVKLHVRKNDTVLVIAGNDKGKTGKVLRVFPQKNRVIVEGVNIRKRHVRPTQSHPQGAIIEREFPIHASNVKKS
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PAGP_PECCP
Sequence: MYLKRTLITLSLITLPIVPFLSYAAESINNTSSTENLAPVTVDSSDPVSDKQGESWWQRSKNNLSTTWNAPQSHDIYIPAITWHNRWTYDKEKTDRYNERPWGAGYGVSRLDKDGDWHGLYIMAFKDSFNKWEPIGGYGYEKRWRPTSDQDFQLGLGFTAGVTMRDNWNYIPIPVLLPLASISYSKLSFQATYIPGTYNNGNVFFAWLRWQI
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: Y232_HELP2
Sequence: MKKPYRKISDYAIVGGLSALVMVSIVGCKSNADDKQKEQSSLSQSVQKGAFVILEEQKDKSYKVVEEYPSSRTHIIVRDLQGNERVLSNEEIQKLIKEEEAKIDNGTSKLIQPNTNNGGSNEGSGFGLGSAILGSAAGAILGSYIGNKLFNNPNYQQNAQRTYKSPQAYQRSQNSFSKSAPSASSMGTASKGQSGFFGSSRPTSSPAISSGTRGFNS
What are the official names of this protein?
UPF0323 lipoprotein HPP12_0232.
What is the protein family that this protein belongs to?
Belongs to the UPF0323 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RECO_ANAMM
Sequence: MQWREMGVVMGTRPYGDEHLLLSILTRNRGLRRGLTRFTKKRPLQIGDLIDATWRAKLPTNLGHFTCEVIASAFYSYFRDRIKLMCLSSITHIMSTALPENEPHPTLYDSFQDFAAAAEAEAPWYNHYLKLELLVLSQLGFALDLSKCAVSNSKDNLLFISPKTGRALSEAVGCAYRDKLLPLPKVLRSISCGVETECCSADEFALSLRILGFFLRRHLLQESHTFQESRKILTGLLG
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: URED_KLEPN
Sequence: MLPPLKKGWQRTLDLRFQQAGGKTVLASAQHVGPLTVQRPFYPEEETCHLYLLHPPGGIVGGDELTISAHLAPGCHTLITMPGASKFYRSSGAQALVRQQLTLAPQATLEWLPQDAIFFPGANARLFTTFHLCAFSRLLAWDLLCLGRPVIGETFSHGTLSNRLEVWVDDEPLLVERLQLQEGELSSVAERPWVGTLLCYPATDALLDGVRDALAPLGLYAGASLTDRLLTVRFLSDDNLICQRVMRDVWQFLRPHLTGKSPVLPRIWLT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_ECO7I
Sequence: MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: AVR2B_XENLA
Sequence: MGASVALTFLLLLATFRAGSGHDEVETRECIYYNANWELEKTNQSGVERLVEGKKDKRLHCYASWRNNSGFIELVKKGCWLDDFNCYDRQECIAKEENPQVFFCCCEGNYCNKKFTHLPEVETFDPKPQPSASVLNILIYSLLPIVGLSMAILLAFWMYRHRKPSYGHVEINEDPGLPPPSPLVGLKPLQLLDIKARGRFGCVWKARLLNEYVAVKIFPVQDKQSWQCEKEIFTTPGMKHENLLEFIAAEKRGSNLEMELWLITAFHDKGSLTDYLKGNLVSWNELCHITETMARGLAYLHEDVPRCKGEGHKPAIAHRDFKSKNVLLRNDLTAILADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDSFLRIDMYAMGLVLWEIVSRCTAADGPVDEYLLPFEEEIGQHPSLEDLQEVVVHKKIRPVFKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERISQIRKSVNGTTSDCLVSIVTSVTNVDLPPKESSI
What is the function of this protein?
Receptor for activin A, activin B and inhibin A.  Involved in transmembrane signaling.
What are the official names of this protein?
Activin receptor type-2B, Activin receptor type IIB, ACTR-IIB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TCPR1_XENTR
Sequence: MPSTVLWATDIFGKVFTLSTDGQQWAPCKNGHVEFKRVSAVRSCCWGVGCNHQIYLYVHASDLPIRYQEETYENQRWNPVDGYCEKLLPSDRWQWSDVTGLRHQQLESFMLPSPHWEWESDWYVDENIGGEPTEKGGWTYAIDFPATYTKDKKWNSCVRRRRWIRYRKYKSRNTWAKIPSHEDNKKLPDPFNDITVGGWEITDEPVGRLSVWAASLQGKVWYREDVCQNIPEGSSWTELETPSEVIQISCGPNDLLWASLWEGQAMVREGINRNNPKGSSWTIVEAPTPENGIMHVSVGVNVVWAVTKDRKVWFRRGVNSHNPCGTGWIEMVGEMAMVDVGLNDQVFGVGYEDRAVYFRQGVTPSELSGKAWKSIVVPRGNERSNSESPNSLLSAGCFFGDEIKEHSDSPIPSDIESSSEPEQSAVQENSSDSSEPADVGPSQQDEPKDEELSAVLELDGQQKAGSSLSKDSGEDSAHSAGPVPKAGAPKWTSIDLLEARINPARASGDMTGLSTLGIFTAGEEESFVCETHPLWTWVSGGGCLVESHTPLKWFTLQTGLSASMQSLSLSITPAHTAAWRKQIFDQLSERSKRELDSFRHYEQAVEQSVWVKTGALQWYRDWKPNKWIDVRVALEQLTGTDGSRDSILFVYYTHGEEKKYIHIFLNEVTILVPVANEAKHSFAIYTPEKTKQRWPIRLAAATEQEMHDWLVLLSMSCYESRKLQGAPSSQAIWSVTCKGDIFVSEPKADLESVTNGRSCDQMFWRQIGGHLRMVESSSNGVVWGLGYDHTAWVYTGGYGGGFFPGIASSTDNIFPQTDTKCVYIYENQRWNPITGYSSTGLPTDRYMWSDASGLQECTKTNTKPPSPQWTWVSDWYIDFNVPGGTDREGWQFAADFPASYHGYKTIKDFVRRRRWARKCRIVTSGPWLEVPPICLWDISISPSSGAHNSESIALWAISNKGDVLCRLGVTKQSPSGSSWLHVGTDQPFISVSVGGCLQVWAIARDGSAFYRGSVSPAQPAGDCWYHIPSPHKQKLQQVSVGHTSVFVVDENGNLWFRHGITPTYPQGTTWEHMSNNIRKVSVGPLDQIWVIADKVQGSHSLSCGTVCHRLGVQPMQLKGHSWDYGIGGGWEHITVRGNRADMAKTLQPKENATEKPDPQEENGESAFSHIANC
What is the function of this protein?
Tethering factor involved in autophagy.  Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes.  Binds phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes (By similarity).
What are the official names of this protein?
Tectonin beta-propeller repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TECPR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes (By similarity).
Protein: MSRA_VESOH
Sequence: MQTAYFSGGCFWCVEAIFQRIVGIIKLTSGYCNGNTSNPTYQDICLGVTGHAEVVKIEFDEFKISFKVLLDIFFEIHNPTTLNQQGNDRGTQYRSAIFYINNKQQLQAINMINLMSDNIVTQVTKLDCFYPAEDYHQNYFNNNLSKPYCQMLIRPKLDKYFSQ
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.