PharMolix/UniProtQA huggingface dataset:
Protein: RR10_GUITH
Sequence: MQKQKIRIRLKGYETNLLLDSCNKIIETATRTNSVTAGPIPLPTRRKIYCVLRSPHVNKDSREHFETRIHKRVIDIYEPNSTTIDSLMKLDLPAGIDIDIKI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PLEK_CANLF
Sequence: MEPKRIREGYLVKRGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVFKITTTKQQDHFFQAAFLEERDSWVRDTKKAIKCIEGGQKFARKSTRRSIRLPETVDLGALYLSMKDIEKGIKELNLEKDKKIFNHCFTGNCVIDWLVSNKSVRNRQEGLMIASSLLGEGYLQPAGELSKNAADGMAEHPFLDNPDAFYYFPDSGFFCEENSSDDDVILKEEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAAGGEEPLGAIHLRGCVVTSVESNPDVRKSEEENLFEIITADEVHYFLQAATPKERTEWIKAIQVASRTGK
What is the function of this protein?
Major protein kinase C substrate of platelets.
What are the official names of this protein?
Pleckstrin.
Protein: NACA5_ARATH
Sequence: MPGAIVEEEKSQIESIKEQLKLEKEDDVVVEDVKDGEEEDDDEDDEDVEVEGEGGNENAKQSRSEKKSRKAVLKLGMKPVSDVSRVTIKRAKNVLFVISKPDVYKSPNAETYVIFGEAKVDDLSSQLQTQAAQRFKMPDVTSMLPNAGSEATMAPLAEEEDEDDVDDTGVEARDIDLVMTQAGVSKAKAVSALKANDGDIVSAIMELTT
What is the function of this protein?
May promote appropriate targeting of ribosome-nascent polypeptide complexes.
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha-like protein 5, NAC-alpha-like protein 5, Alpha-NAC-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
Protein: RSKA_MYCSK
Sequence: MTEPNNTDLLDLATPYALHAVSIDERFEIDRWLATAPPEVADAFTDEVRSVQETMAVLSAATATEPPAHLRDNVLAMVADDPVRDLGSARRRRGGESRWRTAVLAAAAVAVVGLGALGVGLALRPAVSPTTADQVFAAPDVQTVSGPIPGGGTATVVFSKERDAGVLVMNDVAPPKPGTVYQMWLVGSDGPHSAGTMDDKAISPSTTAVLSDIGTSQALAFTVEPPGGSQRPTSPAFAELPLT
What is the function of this protein?
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK.  ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP).  RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor (By similarity).
What are the official names of this protein?
Anti-sigma-K factor RskA, Regulator of SigK, Sigma-K anti-sigma factor RskA.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-K factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: XYLA_ENT38
Sequence: MQAYFDQLDRVRYEGPKSTNPLAFRHYNPDELVLGKRMEDHLRFAACYWHTFCWNGADMFGVGSFDRPWQQPGEALELAKRKADVAFEFFHKLNVPYYCFHDVDVSPEGASLKEYLNNFAQMVDYLGEKQQQSGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMNATHKLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKIGFRGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRGDPQLGWDTDQFPISVEENALVMYEIIKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKVAARMIEDGELDKRVAKRYAGWNSELGQQILKGQLSLAEIAKYAEQHSLAPSHQSGHQELLENLVNHYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMB_SALA4
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVGERARSLGITHIISSDLGRTKRTAEIIAQACGCDITFDSRLRELDMGVLEKRQIDSLTEEEEGWRRQLVNGTQDGRIPGGESMQELSDRVHAALASCLELPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRIDYQESQWLASGWVVETAGDVSHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: RL16_LEUMM
Sequence: MLVPKRVKFRRVHRGHMRGEAKGGKTVTFGDFGLQATTSSWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTSKGVGVRMGNGKGAPEGWVEPVKRGKVMFEVAGVPEATAREALRLAQHKLPVRTKIIAREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: UP02_DAUCA
Sequence: VGLVFNPYNR
What are the official names of this protein?
Unknown protein 2.
Protein: FTSZ2_HALVD
Sequence: MQDIVREAMERDEAERQTQSSLEDSDDQFGDPRIVIVGAGGAGNNTINRLYNIGVEGADTVAINTDKQHLKMIEADTKILVGKSLTQGLGAGGDPSMGERATEMAQGTIKDVLGDADLVFVTAGMGGGTGTGAAPVVAKIAKEQGAIVVGMVSTPFNVERARTVKAEEGLENLRNEADSIIVLDNNRLLDYVPNLPIGKAFSVMDQIIAETVKGISETITQPSLINLDYADMSTIMNQGGVAVMLVGETQDKNKTQEVVNDAMNHPLLDVDYRGASGGLVHITGGPDLTLKEAEGIASNITERLEAAANVIWGARIQDEYKGKVRVMAIMTGVQSAQVLGPSTQKQADKSRQSIQSRESQQQHSGSEFDSSERAQTAQSGTWSDGGRDEVEKNNGLDVIR
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity (By similarity).  Required for division ring constriction (PubMed:33903747).
What are the official names of this protein?
Cell division protein FtsZ 2.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: SYPL1_MOUSE
Sequence: MASKANMVRQRFSRLSQRMSAFQINLNPLKEPLGFIKILEWFASIFAFATCGGFKGKTEIQVNCPKVGVNKNQTVTATFGYPFRLNQASFHTPPNVSVCDVNWEKHVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTNLYRDSRKLPMIDFIVTLVATFLWLVSSSAWAKALTDIKVATGHRIVEELEICNPESGVSCYFVSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSASHSQGGGPPTSGM
What are the official names of this protein?
Synaptophysin-like protein 1, Pantophysin.
What is the protein family that this protein belongs to?
Belongs to the synaptophysin/synaptobrevin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Melanosome. Note=Cytoplasmic transport vesicles.
Protein: ATPD_EHRCR
Sequence: MIQYRGGYIASCYAQALFSVSSNVNSICKNAEFVVSVLENCNDISLFLSNPRVSREDKVKLVEVIGDYIDSILVKFIMVVIENNRGNILLQILNTFLDLVKKHNREVSISVTSCAVLTKQEEEGICDALFEKYGKVVSITNNIDPSILGGFIIRVNFDVIDVSLNSYLQSLRELSKMAIRSSISE
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AMIB2_MYCBO
Sequence: MDPTDLAFAGAAAQARMLADGALTAPMLLEVYLQRIERLDSHLRAYRVVQFDRARAEAEAAQQRLDAGERLPLLGVPIAIKDDVDIAGEVTTYGSAGHGPAATSDAEVVRRLRAAGAVIIGKTNVPELMIMPFTESLAFGATRNPWCLNRTPGGSSGGSAAAVAAGLAPVALGSDGGGSIRIPCTWCGLFGLKPQRDRISLEPHDGAWQGLSVNGPIARSVMDAALLLDATTTVPGPEGEFVAAAARQPGRLRIALSTRVPTPLPVRCGKQELAAVHQAGALLRDLGHDVVVRDPDYPASTYANYLPRFFRGISDDADAQAHPDRLEARTRAIARLGSFFSDRRMAALRAAEVVLSSRIQSIFDDVDVVVTPGAATGPSRIGAYQRRGAVSTLLLVVQRVPYFQVWNLTGQPAAVVPWDFDGDGLPMSVQLVGRPYDEATLLALAAQIESARPWAHRRPSVS
What are the official names of this protein?
Putative amidase AmiB2.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: RPOC1_OLTVI
Sequence: MPTGSPVDATEGSNHSTRRGVLKKRVASFSNGIHIKSIRIGLASPERIRQWAERVLPDGTVVGQVTNPQTVNYKTLKPEKGGLFCEQIFGSIQDTDLTTTRDRRSRLGYIQLVSPVTHVWYLKALPSYIAILLDLPKKHVESISYCTETLSVPVAVHQTTGTLAPNTSTGRATTETNGDRGHASPISVELNPSTNQNSMELFDAPRLTKSSSNLKLTSDLGKAKQPLLLWESSSRSKWLRGNHGDFQANSNLIFQLNEKCLWFNTFYNSLKLEKSWNLEFPESARNSFVKKKPSKSPTGPSNTSSGDSLGKDGTMDHVSPHKANLWGSSPLKREGWVKSAQQTLTQGSQSYPYANGLSFNEGKSKEMGVGALRPQGSENSLFGTHDPFDHLSTHQVKSEQNLFKTPTFDNSKQSNTAENRDSFSRTSARSWIINNYYSVLQTCRWKSPSDWDLFLFYMTSSVNSLDKPIPCYQNRIYDSSGLPFDFPISGGAAIRNLLLNFDPVREDLSLIARQIENQSAKYNQEIRVLEQLYVNGLFMTRTQRKVLFALWRQRTKVLRRLKLVRYFRQTNMRPQWMVLSVLPVLPPDLRPIIQMNGNQVAVSDLNKLYQKVIFRNQRMLRFARGQYTINNSPEMRYAGRLLQEAVDALIANGKGGGATISDANNRPLKSLSDMLKGKKGRFRQNLLGKRVDYSGRSVIVVGPKLKLHECGLPKEMAIELFQPFLIRQLRTNKIAATIVGAKKLIRSGDQIIWEVLKQVLQNHPILLNRAPTLHRLGIQAFQPKLVDGRAILLHPLVCPAFNADFDGDQMAVHVPLSYEARSEAWKLIWARNNILSPATGEPILTPSQDMILGCYYLTTTDRIRFKSTWLASKSQQTGDSEASFAMLRPKHGPSGRKPTQDLCTKGSAFFAPDNTAKQSEASFALSFFSSQEEVLLAYHHHKLSLHSLIWLKWEQDFEANTTFESPLEIRVDKNGNSTHLYRNNLYRFNSKGEKLQQFIRTTPGRILLNQTISQTLFTKQV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOB_FUSNN
Sequence: MQKLIERLDFGKIKARGEMPHFLEFQLNSYEDFLQTNMSPNKREEKGFELAFKEIFPIESSNGDVRLEYIGYELHEAEAPLNDELECKKRGKTYSNSLKVRLRLINKKMGNEIQESLVYFGEVPKMTDRATFIINGAERVVVSQLHRSPGVSFSKEVNTQTGKDLFSGKIIPYKGTWLEFETDKNDFLSVKIDRKKKVLATVFLKAVDFFKDNNEIRDYFLEVKELKLKALYKKYSKEPEELLNVLKQELDGSIVKEDILDEETGEFIAEAEAFINEEVINKLIENKVDKISYWYVGPESKLVANTLMNDTTLTEDEAVVEVFKKLRPGDQVTVDSARSLIRQMFFNPQRYDLEPVGRYKMNKRLKLDVPEEQISLTKEDVLGTIKYVIELNNGEQNVHTDDIDNLSNRRIRGVGELLLMQIKTGLAKMNKMVREKMTTQDIETVTPQSLLNTRPLNALIQDFFGSGQLSQFMDQSNPLAELTHKRRISALGPGGLSRERAGFEVRDVHDSHYGRICPIETPEGPNIGLIGSLATYAKINKYGFIETPYVKVENGVALVDDVRYLAADEEDGLFIAQADTKLDKNNKLQGLVVCRYGHEIVEIEPERVNYMDVSPKQVVSVSAGLIPFLEHDDANRALMGSNMQRQAVPLLKSEAPFIGTGLERKVAVDSGAVVTTKVSGKVTYVDGKKIIIEDKDKKEHIYRLLNYERSNQSMCLHQTPLVDLGDKVKAGDIIADGPATKLGDLSLGRNILMGFMPWEGYNYEDAILISDRLRKDDVFTSIHIEEYEIDARTTKLGDEEITREIPNVSESALRNLDENGVIMIGSEVGPGDILVGKTAPKGETEPPAEEKLLRAIFGEKARDVRDTSLTMPHGSKGVVVDILELSRENGDELKAGVNKSIRVLVAEKRKITVGDKMSGRHGNKGVVSRVLPAEDMPFLEDGTHLDVVLNPLGVPSRMNIGQVLEVHLGMAMRTLNGGTCIATPVFDGATEEQVKDYLEKQGYPRTGKVTLYDGRTGEKFDNKVTVGIMYMLKLHHLVEDKMHARAIGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGASNILQEMLTVKSDDITGRTKTYEAIIKGEAMPESDLPESFKVLLKEFQALALDIELCDEEDNVINVDEEIGIEETPTEYSPQYEIEMTGLHEIDEDAEDFEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: NDB4W_CHATC
Sequence: MKTQTVLFSFFLVLLLVATQTEGGILDALTGILGKRALRNQNFVDYAYDPSLSAADWRALETLLEDY
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Peptide Ctri9293.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL23_HERAR
Sequence: MSAVIKHSEERLMKVLLAPVISEKATFVAEKNEQVVFLVMPDATKLEIKAAVELLFKVQVESVQVANRQGKQKRSGRFNGRRNHTRRAFVCLKPGQEINFTEEAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HEMH_YERPB
Sequence: MMQSKPGVLMVNLGTPDAPTSKAIKRYLAEFLSDRRVVDTSPLLWWPLLHGVILPLRSPRVAKLYQSVWMEEGSPLLVYSRRQQKALAARMPDIPVELGMSYGSPNLPEAIEKLLAQGVTNLVILPLYPQYSCSTSAAVWDAVARVLKGYRRLPSISFIRDYAEHPAYISALKQSVERSFAEHGQPDRLVMSFHGIPKRYAQLGDDYPIRCEDTSRALRAALPLPAEKIIMTYQSRFGREPWLTPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEIKEQNREFFLHAGGEKFEYIPALNDDEGHIALLEQLIRHNI
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFMP_BACSU
Sequence: MEWMKIDQVAKRSGLTKRTIRFYEEIGLIPAPKRTDGGVRLYSEDDMEELEKVISTKEVLGFSLQELQHFMETSRQLELNKEGYLLSLDPKERKEKLEEIQETLNHQLDLIDEKIRTFQSFKERLQGMKGKAERAIQSIE
What is the function of this protein?
Repressor of the yfmOP operon.  A mutation in yfmP leads to overexpression of yfmO, probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA.
What are the official names of this protein?
HTH-type transcriptional regulator YfmP.
Protein: MEPA_PECAS
Sequence: MKQGLIGVLALALGATLLSSAVWAKTPWQEIAHPVAGTPQSIGSFSNGCIIGAQPLPLQSLDYQVMRVDQRRYFGHPDLLAFIHRLSTEVKRTTSGNVLVGDMGMPVGGRFSSGHASHQSGLDVDIWLQLPRQRWSEQQLLKPQPIDLVNASGLNVNPRVWRPEVTTLIKTAALDSDVTRIFVNPAIKKQLCAEAGHDRDWLRKVRPWFAHRAHMHVRLRCPADSLECQEQSEPPIGDGCGAELTSWFQPKQPSSEAPEKTTPPPLPPSCQALLDRHFAAR
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL28_CORGL
Sequence: MSAHCQVTGRKPSFGKSVSHSHRRTSRRWNPNVQRRKFYVPSEGRTITLTVSTKGLKVIDRDGIEAVVAQIRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CYSC_SALPB
Sequence: MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: SODM_RABIT
Sequence: HGRGMKHSLPDLPYDYGALEPHINAQIMELHHSKHHAAYVNNLNATEEKYREALARGDVTAHVALQPALKFKGGGHINHTIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKERLTAVSVGVQGSGWGWLGFNKEQGHLQIAACANQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVITWENVTERYMACK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y3232_SINFN
Sequence: MTIAAGTDDNRQRSTWIWLIACLGVVAIQILTQHLMGRLWICECGYVKLWEGVVNSSGNSQHISDWYTPSHIIHGFLFYGLGYLLLRGKPLSVRLLLATLIESAWEIAENTPMVINRYRSATISLDYFGDSILNSTMDTLAMAAGFLLASRLPVAVTVTIAIVLELFTGWIIRDNLTLNVLMLVWPLDAVKAWQAGL
What are the official names of this protein?
UPF0314 protein NGR_c32320.
What is the protein family that this protein belongs to?
Belongs to the UPF0314 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BCR1_CANAL
Sequence: MSGTSQVLQNDSHQSQHASMAYNQRQPMMYPPPPQQQPLHSQNSLPPLPPIPAPSLPPISNNISNGNTNELNNNNQQQQQHGQPPLPPPPINANQQYYAVPPLRAPPPLNTLSSVVNSLPTLTPTLTNATHSTMSSNSSAESSASSSSNSITKPKSKRSSKGRVFQCTGYPGCNMSFTRSEHLARHKRKHTGERPFTCPYCSKNFSRLDNLRQHKQTVHAYETYLTKDNRDSKLLIERSKSKKKLKQQEKKAQQQAQLQAQAQAQAQAQVHMQQHQQNGYNFQPPYPQFHNQYYANNQYQGPQPPPPPAPQQQVPGQQQPQPQQGMPAGYLDPYRQYPPNTTFDPMALPPPPKINAHPQKPLPPLPHQMGGGQEQPSDNVSQQGLKIPDHAFTPKRRPEPLALQHSTHSNENISNEGNINANTNTNMNTVTSSITSDAVYPPPPRSATSAASLTPNLASPLSPLFHQSFSQTTLKSTPDPRGSTITNSSISIKSPMSQHFSILSGNSNYSNNTTNSLPSVSNLPHPNWGSTNGTTGSNGTSGGSYQQNSFHQRQSSVVSDFSIFSNSDNRKDIKSNWLKGVLNDDNNNNNNNNNEQQQQQLQDPKLASPAPTLPPVSSITGGGTSNGNDSMMVDNMENKNDVSQSNVIIDSNNNNGDKMVNKLNFQSIELHDNNNNNTPSIKSTHSTETIQTTMVVVNKSDPPPLSTPTTNTNTNTNSTATTNATGYVSKKPTINNLISQ
What is the function of this protein?
Transcription factor which acts as a master regulator of biofilm formation (PubMed:15964282, PubMed:17030992, PubMed:16839200, PubMed:20223293, PubMed:19959578, PubMed:20705667, PubMed:21829325, PubMed:21283544, PubMed:21407800, PubMed:22145027, PubMed:22265407, PubMed:22882910, PubMed:22589718).  Biofilms play an important role in pathogenesis and produce many infections such as oropharyngeal candidiasis or vulvovaginal candidiasis (PubMed:20705667, PubMed:21283544, PubMed:21407800, PubMed:22544909, PubMed:22265407).  Controls the expression of genes that govern cell-surface properties such as ALS1, ALS3, HWP1 and HYR1 (PubMed:16839200, PubMed:17277173, PubMed:19197361, PubMed:20415594, PubMed:22145027, PubMed:22544909, PubMed:22589718).  Down-stream component of the hyphal regulatory network that couples expression of cell-surface genes to hyphal differentiation (PubMed:20223293, PubMed:21407800, PubMed:22359502).
What are the official names of this protein?
Biofilm and cell wall regulator 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPD_BURCH
Sequence: MTPRLFALIPCAGTGSRSGSAVPKQYRTLAGRALLHYTLAAFDACSEFAQTLVVLAPDDSHFDARRFAGLRFAVRRCGGGSRQASVLKGLLELAEFGATDHDWVLVHDAARPGITPELIRTLVATLKDDPVGGIVALPVADTLKRVPAGGDAIARTESRDALWQAQTPQMFRIGMLREAILQAQREGHDLTDEASAIEWAGHTPRVVQGSLRNFKVTYPEDFALAEAILARPANAS
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PHNX_BACFR
Sequence: MKKIECIIMDWAGTAVDYGCFAPVAAFIKAFAGKGLTIDVEQTRKPMGLPKIQHIRELLTMPEVNEQFINRYRRAWTEEDVVELNHLFEKYLFASLKEYTDPIPGVIPTLEKLRAEGLKIGSTTGYTREMMDVVLPEAQAKGYRVDYCATPNLLPAGRPAPYMIFENLTKLAVPDPDTVVKVGDTIADIQEGVHAKVWSVGVVLGSNEMALTEEETHALPAAELENRIAEVKQRMLAAGASYVIRSIEELPALIQLINSKLNH
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: ECM14_SCHPO
Sequence: MAYNKSLKSLVFILLASQIVFVLFLCYGKSSRELGVKWNSDIRSWMTSYVGFNGETAAISEEQLIWAEKIPDYNEEIVVRLHLEEENNLSDILQKAQSQNLDIWDYNFDHVDLRLKEENFDFWKSQYRSDILINNLTETLFESIVPDTTNSPFSTEAFLQAVENGHLNHEMFTSFTDIFFKSYQNLESINSWLRLMASLYKDLSELVPVGITAEGRTILGLKLNGRHPSDNGEKIRNKKVIIIQGGSHAREWIGIPSVCYAAWQLLAKYDSDGHVRKLLDKFEWIFIPVLNVDGYEYTWSNDRLWSKNRQPLNNSECFGINLDANWAFGFNGNIDPCSNEYGGLSPFQANETMALFNLITESLSQEQKKVVGFLDVHSYSQSVLWPYAYTCDLFPPDTENFEELAIGLVKELHRVNSRYYTYQQACIPYDGFHKHYLPGTAIDWVYFAADVAWPFNIRLRDMGDYGYLLPAKQIVPTAKEFFAMILYYGEFIAEYAF
What is the function of this protein?
Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
What are the official names of this protein?
Inactive metallocarboxypeptidase ecm14.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Secreted.
Protein: ACCD1_VIBC1
Sequence: MSWLEKILEKSNLVSSRKASIPEGVWTKCTSCEQVLYHAELERNLEVCPKCNHHMRMKARRRLETFLDEGERVELGTELEPQDKLKFKDSKRYKERISAAQKSSGEKDALIVMQGELLGMPLVACAFEFSFMGGSMGSVVGARFVKAVEAAIENNCALVCFSASGGARMQEALMSLMQMAKTSAALERLSDKGLPFISVLTDPTMGGVSASLAMLGDINIGEPKALIGFAGRRVIEQTVREDLPEGFQRSEFLLEHGAIDMIVDRREMRQRVGGLVAKLTNHKSPMVVSVNESPNEEPYSVPEADEKG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 1, ACCase subunit beta 1, Acetyl-CoA carboxylase carboxyltransferase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCR_HUMAN
Sequence: MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV
What is the function of this protein?
Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins.  The C-terminus is a GTPase-activating protein (GAP) domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42.  Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form (PubMed:7479768, PubMed:1903516, PubMed:17116687).  The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1.  Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form (PubMed:7479768, PubMed:23940119).  The amino terminus contains an intrinsic kinase activity (PubMed:1657398).  Functions as an important negative regulator of neuronal RAC1 activity (By similarity).  Regulates macrophage functions such as CSF1-directed motility and phagocytosis through the modulation of RAC1 activity (PubMed:17116687).  Plays a major role as a RHOA GEF in keratinocytes being involved in focal adhesion formation and keratinocyte differentiation (PubMed:23940119).
What are the official names of this protein?
Breakpoint cluster region protein, Renal carcinoma antigen NY-REN-26.
What are the subcellular locations of this protein?
Postsynaptic density. Cell projection, dendritic spine. Cell projection, axon. Synapse.