PharMolix/UniProtQA huggingface dataset:
Protein: HTPX_TOLAT
Sequence: MKRVLLFLATNLAVMLVLSIVLSVLSSFFGISTRGSGGLLLMAAVFGFGGSIISLLMSKWMAKRSYGVQVIEQPRSEIEYWLFNTVQRQAQQTGIGMPEVGIYDSPDMNAFATGANRNKALVAVSSGLLYNMSRDEAEAVLAHEISHVANGDMVTLTLIQGVVNTFVIYISRVLAGIVSNFMRSDDEESSATGGIAYFAISMVFELIFGILASTIVMWFSRQREFRADAGSAKLVGKDKMIAALERLARGHDSQLDGSMMAFGINGKTAMTELFMSHPPLEKRIQALREMR
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPF_SHIBS
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RAP94_FOWPN
Sequence: MENKESVLLELVPKIKAYIKDDTVKEKSYQDFIEKNKELFICNLYNVNMITDEDIKLLYITIEQNIDIDDKSLVAIFSYIGYNFEKNIHDDNSSIDLGDRMTGDMNYNMYDTFFSTLDFIIRQKHVNILVNDEGNNDFNINYRSFTTSLSYKEDKYEQVVNEIPFNMKELLSYVSKNLDQLRFSKKYLDFAYLCRNIGIKISKRKYNVRYIFNYVIDELTIPIVIKDYLDVKYVYLEETNKAYRNNFDNDNKYFYEWGKVIIPKFKNPRLYSYFFLSNYGLCDLFMELINIKQVTFEPRKNPIEYIYVSELKFWEEGGSVDFVPCEHEIAIIDAKKVSLEYYENINKFIAKYIYYEDGLAYCNLCGINIQELNLDATDVTKISLINVTYNKSIFMSEPYNYFSHSQRFIFNTIMSFDTIMKSQMWNMKYNINRLILNFLIDINSKRHEYEKQFATEIKKGIFFLRLSANLFDIQMSSMELFYSAKILNIHFIVALVIVLNSGADFIMYYMTNKKEETNYSDLNHIISVIVFDFLKKTRTVDSKQFNTIELFTETYMKIATEELIVHYNRIKLEMERLIAIKKDRKTPNYDISIYRQIQRTDEIAFFPSCITSTKLFITYEKVVAENTEIITIKHPVRIKEGTDEDKEIFEDIMKKTTKVLIRVNDTNAYNASFFTTHIKLEVEKKKIIIPLTSLFVYNVLKYYSSNVDFYVFKFGDPFPFHYDLISQEHTNHKITGYNMLRQELLPNSNVFTYFSDSLNRQELEFSFYMFLASYVNVTEWIEENSKKIKELYIINFNN
What is the function of this protein?
DNA-directed RNA polymerase-associated factor required for the transcription of viral early genes as well as for transcription termination.  Within minutes after virus entry, recruits the core RNA polymerase, the early transcription factor (ETF) and other enzymes needed for transcription initiation, elongation, and termination thereby allowing synthesis of early mRNAs which are extruded through pores in the core particle.  Recruits the multifunctional J3 protein, with poly(A) polymerase-stimulatory, cap nucleoside-2'-O-methyltransferase, and transcription elongation activities.  Interacts with NPH-I, a DNA-dependent ATPase required for the termination of early transcripts.  Acts as a transcription termination factor by binding, together with the capping enzyme/VTF, to the termination motif 5'-UUUUUNU-3' in the nascent mRNA.  Involved as well in the packaging of RNA polymerase and other components needed for early transcription in assembling virus particles (By similarity).
What are the official names of this protein?
RNA polymerase-associated transcription-specificity factor RAP94, Protein H4, RPO-associated protein of 94 kDa.
What is the protein family that this protein belongs to?
Belongs to the poxviridae protein RAP94 family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.
Protein: RS8E_THEVO
Sequence: MTIFQGKSGKKPTGGNLKQAKKKRRFELGREPTLTKLGTKVERKVIRTMGGNSKAILFTADTANVYDIHEKKIKKVKIITVKENPANSHYVQRNIINKGTIISTEIGEAIVTSRPGQDGVINAKLLN
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: PRM1_SCHPO
Sequence: MASSYLSLAARLSQCWISPWSLCCLYILMQFFLFTKDLNTKIGDFVNDEQATCNYIQEKVDILLDSPSLIANAAVRVAKDGIQSTVKIILSGISDSLIAAENVFIFFIEFSYGTYLCLIQLAIDGILDAVADVGEEIGTAVNDTLHAIADEIEDTVSSLNEVFQSAEDSLEKVASWLGEDINLPNVSIPEIQSLRNFTLSSSYDTEFEKLKAGVNFDSAINATKAAISKPFSSARNLILEKVSNYSFDTSMVSSPNKTHVVVCSTDDLTAISSFILSSIYKIRKVVIISLLIIIAGLFLISSIYEIWKWCRIRHKAFLLDEHIRSNKFEDTRDLISYIESPISWNLKYFISALPLPCFLSVQLRWFITYIFHPPAAMILFISCTSFISGILQLVLLNNIREDGSVISALAQNSFHKVESALANVSVAWANSTNQIILKNQENINNNMFGSIHNTTLSLNSTLNTFMNELNSSMTSAFGDTFLASTVQNVMNCLLYRKIENFEEVLTWVYNKSHIELPLLPTDILSKSIDNQTIYSSLYSSLNSSNSTVSFSGIFDRVEKSVISELNFSFLFFLLWLLICAFGLIGVLSSWLKSLFLSLLDLVIPNPKENITLPVQSLAFPVTKSCRPPPIPPRESHVYDFQNFQYEEDDCIDYKRSLGLISLSSDLAIDIPISPAIISDIQFNSITTESEETTYLLKEKQDRY
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein prm1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DIXC1_HUMAN
Sequence: MLACLTRGNLLDVLQEGFNEQQLQAYVAWVNAQLKKRPAVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPGNQQEMKNNVEKVLQFVASKKIRMHQTSAKDIVDGNLKSIMRLVLALAAHFKPGSSRTVNQGRDSRAPLQSHRPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIIPAEGIENRTEGTDSPLSRDWRPGSPGTYLETSWEEQLLEQQEYLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIQSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLDERNRLLGEYKKELGQKDRLLQQHQAKLEEALRKLSDVSYHQVDLERELEHKDVLLAHCMKREADEATNYNSHNSQSNGFLLPTAGKGATSVSNRGTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMETQKKQERKVRVKSPRTQVGSEYRESWPPNSKLPHSQSSPTVSSTCTKVLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFHDDDAIPGWEGKIVAWVEEDHGEN
What is the function of this protein?
Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2.  Regulates JNK activation by AXIN1 and DVL2.
What are the official names of this protein?
Dixin, Coiled-coil protein DIX1, Coiled-coil-DIX1, DIX domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DIXDC1 family.
What are the subcellular locations of this protein?
Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm. Note=Colocalizes with gamma-tubulin at the centrosome, both during interphase and mitosis (PubMed:19375513). Associated with actin stress fiber at the filament ends (PubMed:16814745). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Note=Not associated with stress fibers.
Protein: RL17_CHLT2
Sequence: MQHARKKFRVGRTSSHNRCMLANMLKSLIHNERIETTLPKAKELRRHADKMITLAKKNTLAARRLAVGRLMVRYNTLTSKEARQVKAGDLSAYNVDRRVIGKLFDVLATRFSSRNGGYTRILKLQNRVGDNAQKCIIEFLA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PHEB_PSEUE
Sequence: MTVKIYDTPEVQDFLKIVAGLDQEGGNDRGKQIIHRILSDLYRTIDDFDITAEQYWSAVSLLNALGQASQFGLLSPGLGFDHYMDMRMDAADAEAKRTGGTPRTIEGPLYVAGAPEAEGFARMDDDPDTDGETMWLHGQVRDTAGKPIPGAKVEIWHCNSKGGYSFFDKSQTPYNLRRTIIADNEGYYRARSVIPSGYGVPEGAPTDQVLKLLGRHGERPAHIHYFISAPGHQHLTTQINLAGDPYTYDDFAFATRQDLAAEGKRVENHPAAQQYGVEGTVTEVIFNIELSPTAEEELQARP
What are the official names of this protein?
Catechol 1,2-dioxygenase, 1,2-CTD.
What is the protein family that this protein belongs to?
Belongs to the intradiol ring-cleavage dioxygenase family.
Protein: FABA_ERWT9
Sequence: MVDKRESYTKEDLIASGRSELFGAGGPPLPSGNMLMMDRVVKMTEDGGKYDKGFVEAELDINPDLWFFSCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFSGQVLPTAKKVSYRIHFKRVINRKLVMGVADGEVLVDGEVIYTASDLKVGLFKDTAAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CML17_ORYSJ
Sequence: MACDQQAELRRVFELFDRDGDGRITREELTESLERLGMPVHREELAATIARIDANGDGCVDMDEFTQLYETVMRVDGGGGGGGGACDVDEASMREAFDVFDRNGDGFITVDELGAVLASLGIKQGRTAEDCGRMIGQVDRDGDGRVDFLEFKQMMRGGAFATLR
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML17, Calmodulin-like protein 17.
Protein: YIDD_PROM3
Sequence: MRESNTLSGGIFALLNRAIGSVLLALIGFYRTWLSPLLGPHCRFIPSCSAYGLEAIQRHGPWRGGWLTLRRLSRCHPFTPCGCDPVPD
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CH602_SORC5
Sequence: MAAKEIIYNESARSMILAGVNALADAVKVTLGPKGRNVVIEKSFGSPTVTKDGVTVAKEIELENRFENMGAQMVREVASKTSDIAGDGTTTATVLAQAIYREGSKLVAAGHNPMEIKRGIDKAVEAIVEHLRGSAKQTKDAKEIAQVGTISANGDETIGKLLADAMEKVGKEGVITVEEAKSADTTLDVVEGMQFDRGYLSPYFVTDPEAMKANLEDCYILISEKKISNMKDLLPVLEAIAKSQKQLLIIAEDVEGEALATLVVNKLRGTLHCAAVKAPGFGDRRKEMLKDIATLTDGQVIAEELGLKLENVTISDLGRAKTVIIDKDNTTIVGGQGKKDKIKARQQEIRAQIENTTSDYDREKLQERLAKLVGGVAVVKVGAATETEMKEKKARVEDALHATRAAVEEGIVPGGGVALIRAQSSLEKLKVNDEQRFGVNIIRRAIEEPLRQISANAGEEGSIVVQKVRDGKDSYGYNAASGDYGNLLEMGVIDPVKVVRSALQNAASVASLMLTTEALIAERPKEEKPAAGGAHAGHGHDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAHO_TAPPI
Sequence: APLEPVYPGDNATPEQMAQYAAELRRYINMLTRPRY
What is the function of this protein?
Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2.
What are the official names of this protein?
Pancreatic polypeptide, PP.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14Z_DESDA
Sequence: MSRTSLEVKAKRKPKFSARAYNRCPLCGRPRAFLRQFGICRICFRNMALRGELPGVRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RLR17_PLAHL
Sequence: MREPAFSFRLHLFAAMILLVDVFSALSITTQTFRNVQRHSTDRQLRARDSQAKNYVIRDEERMPLRKLPYDLNLSLSSPPVATLRTALELLYPQAGPSQLWHFEFVTQMKRELSVMQSHPKKLIFDQLIGAMRSMNRNMHMKWNHASDISELSPYTQLILPIALKLRQRLSEGASNDADWMSLLMRLIPYGFLRKEVELLLRTAGYDNVQNYIALYDQMLSKVSAEDTLKFQLLDSNIAPNFQELNKEFLYRSVSLLASKTDGVTADSIVQTTCWSFILIQLTKAKYPQDELQKILEDSMPAEKVVAVMKSYKEGFPNPAHR
What is the function of this protein?
Secreted effector that suppresses pattern-triggered immunity (PTI) in plant host.
What are the official names of this protein?
Secreted RxLR effector protein RXLR-C17.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: CLBA1_BOVIN
Sequence: MQDQRELGGAAGQGLPLCAFLSDLPEQGGGVSLRQVSKDSGAPGRQSGDAVEWARLRCALPPPDGEARTSGGSCEGLSTSTARGPDPGEHSGAWGEFEVFQESSASSEQFCQSFELQERPAASQPWRTASAQKQHGSSQPHQGGVTGTGAIAASELVVSCEDVFRSAFQEVPVPQATEGISTLDHFLEARNEESSGLESAQKLCSESRKLWRALHNTGTMTISRCTWSESRSRENFLPVLGVDAAQKSLSGSPGRTLGEPGLHEPEELGFHLQRCRALIQTKLSGTPTGGQGSLITYSLFLKTPIHGNGQYITTPRKKKTFGPRNLKLTLFNSDIY
What are the official names of this protein?
Uncharacterized protein CLBA1, Clathrin-binding box of aftiphilin-containing protein 1.
Protein: NS1_I57A3
Sequence: MDPNTVSSFQVDCFLWHVRKQVPDQELGDAPFLDRLRRDQKSLRGRGSTLGLNIETATRVGKQIVERILKEESDEALKMTMASAPASRYLTDMTIEEMSRDWFMLMPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTNEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWRSSNENGRPPLTPKQKRKMARTIRSKV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: YIF9_YEAST
Sequence: MNFSTVFQAIIAVLGLTTVTALAEFDFDVGYEEFVRTNPDTIFLESDIGLHVGYTEGGERQIATIPHNSTLGTSLREYSGCGGNGTETSIATPAPTMSEVPIATFVKRRKSVPILLPQVCM
What are the official names of this protein?
Uncharacterized protein YIL059C.
Protein: CSPA_STAEQ
Sequence: MKQGTVKWFNAEKGFGFIEVEGENDVFVHFSAINQEGYKSLEEGQSVEFEVVEGDRGPQAANVVKL
What is the function of this protein?
Involved in cold stress response.
What are the official names of this protein?
Cold shock protein CspA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANA_STAA9
Sequence: MNKDLKGLYAALLVPFDENGQVNEQGLKQIAQNAIETEELDGLYVNGSSGENFLLNTEQKKQVFKVAKEAVGDKVKLIAQVGSLDLNEAIELGKYATELGYDALSAVTPFYYPFTFEEIRDYYFDIIEATQNNMIIYAIPDLTGVNISIEQFSELFNHEKIVGVKYTAPNFFLLERIRKAFPDKLILSGFDEMLVQATISGVDGAIGSTYNVNGRRARKIFDLARQGQIQEAYQLQHDSNDIIETVLSMGIYPTLKEILRHRDIDAGLPKRPFKPFNEAHRQTLDQLIAKYDL
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPDB_LACPL
Sequence: MKRIVVGITGASGTIYAVDLLEKLHQRPDVEVHLVMSAWAKKNLELETDYSLAQLTALADATYRANDQGAAIASGSFLNDGMVIVPASMKTVAGIAYGFGDNLISRAADVTIKEQRKLVIVPRETPLSVIHLENLTKLAKLGAQIIPPIPAFYNHPQSIQDLVNHQTMKILDAFHIHNETDRRWEGD
What is the function of this protein?
Involved in tannin degradation.  Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for gallate decarboxylase LpdC.  The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
What are the official names of this protein?
Flavin prenyltransferase LpdB, Gallate decarboxylase subunit B.
What is the protein family that this protein belongs to?
Belongs to the UbiX/PAD1 family.
Protein: FL2W_MAIZE
Sequence: MATKILALLALLALLVSATNAFIIPQCSLAPSAIIPQFLPPVTSMGFEHPAVQAYRLQLVLAASALQQPIAQLQQQSLAHLTLQTIATQQQQHFLPSLSHLAVVNPVAYLQQQLLASNPLALANVATYQQQQQLQQFMPALSQLAMVNPAVYLQLLSSSPLAVGNAPTYLQQQLLQQIVPALTHQLAMANPATYLQQLLPFNQLAVSNSAAYLQQRQQLLNPLAVANPLVATFLQQQQLLPYNQFSLMNPALQQPIVGGAIF
What is the function of this protein?
Zeins are major seed storage proteins.
What are the official names of this protein?
Protein FLOURY 2, 22 kDa alpha-zein 16, FLOURY-2.
What is the protein family that this protein belongs to?
Belongs to the zein family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Note=The fl2 mutant remains anchored to endoplasmic reticulum membrane while the processed mature form localizes in the lumen.
Protein: MURC_BACLD
Sequence: MTVYHFVGIKGTGMSPLAQILHDNGYNVQGSDIEKYIFTQTALEERNIPIYPFDPENIKPGMTVIAGNAFPDTHPEIEKAQAEGLPVVRYHKFLGDYLKKFTSIAVTGAHGKTSTTGLLSHVIKKAKPTSYLIGDGTGKGCENSEYFVLEACEYRRHFLSYQPDYAIMTNIDFDHPDYFANIDDVFDAFQTMALQVNKGIIACGDDEYLMKIHANVPVVYYGFAEENDFQARNVIKNTEGTTFDVFVRNTFYDTFYIPAYGSHNVLNALAVIALCHYEQVDVDIIKEGLQTFGGVKRRFNEKHAGSQVLIDDYAHHPTEITVTIEAARQKYPERDIVAVFQPHTFTRTQSFLNEFAESLKKADYVYLCDIFGSARENAGKLTIGDLQEKIPQAKLIDENDTSILKEHENAVLIFMGAGDIQKYLRAYENVLA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_SHEB8
Sequence: MTPIFFNQQYPTLVDICARWQLVYDANATFELRFESDTLSLHKRDEPKLDGIVVDFVTGAVAHRRKFGGGRGQSIAKAVGLKQGVMPSVVDGTAGLGRDAFVLASLGCTVTMVERHPVVAALLEDGLRRAYQDAEIGDWMRERMRLFHGSSLEALSKLAQEIDVVYLDPMYPHRDKSALVKKEMRVFQSLVGADLDADGLLAPALALATKRVVVKRPDYAEDLDGVKPNTVIETKKNRFDVYVKAAMK
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_BIFLD
Sequence: MLDVNAFDKIRIGLATADDIRGWSHGEVKKPETINYRTLKPEKDGLFGEQIFGPTRDWECACGKYKRVRFKGIVCERCGVEVTRSRVRRERMGHIELAAPVTHIWFFKGVPSRLGYLLNVTPKDLERVIYFASYMVTEVNEDERHNDLPGLQDEFDSEIKRLEQRRDSDIEARAKKVEEDLAALEEAGEAKGPARTKLRNGAERDMAAIRTRYNDQIARVDAVFDKFKKLKPGDMVDDVDLWREMQDRYGDYFDGCMGAEAIKKRLQSLDLETISKELREEIKDASEQRKTKALKRLKVVNAFLTTGNKPEAMVLDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIELGAPEIMLNNEKRMLQEAVDSLFDNGRRGRPVTGASNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPSLRMHQCGLPKPMALELFKPFVIKRLVDLNYAQNMKSAKRLVDRGDAEVWGVLEEVISEHPVLLNRAPTLHRLGIQAFEPILVEGKAIHLPPLACAAFNADFDGDQMAVHLPLSAEAQAEARSLMMASDNILKPADGHTVTMPSQDMILGLYYLSTVLEGVKGQGRVFSSLEEAEMALDRHEIDMQAKVLIRLPESFVLPKNWEPGEVKVLDPREGEDEVVKEERFHDGTVLFATSYGRILFNETLPTDYPFVNEQVAKGRLSKIVDDIAMRYSTQQVAATLDALKDLGFTRAPWSGVSFAFSDVNEPPERDEKIAEYEAKADKVNANYEMGLLTEEARRQELIDLWTECTAEVSKEVEEKFDPTSNLAIIVQSGARGNMMQINQIAGMRGLVANPKGEIIPRPVKSNYRDGLSVLEYFISQHGARKGLADTALRTAESGYLTRRLVDVSQDVIVREEDCGTKAGLPIRVAERDNDGNLVLVKAADGGPYSRLLAADVIDPADGQTVLYKRDDALSMDVLNDLVAHGVEEVKCRSVLTCESKRGVCAKCYGWSLATNKLVDVGETVGIVAAQSIGEPGTQLTLRSFHSGGVAAASDITQGLPRVTELFEARTPKGEAPITEFAGSIKIVENDRGRQIILTPDADSGAPKEDGVIKPITYQVSKRVPLKVADGDHIKVGTQLVEGSVDPKKILTILGKRAAQVNIVEEVHTVYRSQGVDIHDKHIEVIVHQMTRRVTIIDSGDTDLLPGELVDNARFREINRNIVKNGGRPAVGRPALMGITKASLATDSWLSAASFQETTRVLTEAALSEKVDDLKGLKENVIIGKLIPAGTGLARYRNAVVEPDKAIRDTIYPNFGLGGDGDLGDASFSDADLSDLNFSNLEFGDLKLGDDFNPDDFYSDQGGQPDIEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PDK1_RAT
Sequence: MRLARLLRGGTSVRPLCAVPCASRSLASDSASGSGPASESGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKTIYEFTDTVIRIRNRHNDVIPTMAQGVTEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGSPSHRKHIGSINPNCDVVEVIKDGYENARRLCDLYYVNSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHADKGVYPPIQVHVTLGEEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTESIERLPVYNKAAWKHYRTNHEADDWCVPSREPKDMTTFRSS
What is the function of this protein?
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2.  This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate.  Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia.  Protects cells against apoptosis in response to hypoxia and oxidative stress.
What are the official names of this protein?
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, PDK p48, Pyruvate dehydrogenase kinase isoform 1, PDH kinase 1.
What is the protein family that this protein belongs to?
Belongs to the PDK/BCKDK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL4_SALCH
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.