PharMolix/UniProtQA huggingface dataset:
Protein: MURG_ECO45
Sequence: MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSREILLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROE_TRIV2
Sequence: MITGKTKLLGVIGHPVEHSLSPVMHNAAIAQLGLDYVYLPFPIAPDNLEAAIALLATIGVVGFSVTIPHKQAIIPLLAEISPVAQAIGAVNTVTRQNNQWVGTNTDIEGFIAPLQTTYKRDWSQQIAVILGNGGAARAVVAGCYQLGFAEIHVVGRNVQRLEEFRHSWDNSPIAENLQVHTWDYLAKLVPQANLLVNTTPIGMYPQVDESPLSTEELANLQTGAIAYDLIYIPKPTQFLQKAQQQGAIAIDGLEMLVQQGVAALKIWLQQDDIPVDVMRQALQKHLGLV
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MDTG_ECOL6
Sequence: MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKIMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYSWNSLRRRRIPQISN
What is the function of this protein?
Confers resistance to fosfomycin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YAJ8_YEAST
Sequence: MQTPSENTDVKMDTLDEPSAHLIEENVALPEDTFSSHLSYVLYEIAHCKPIMFMIIIIVSLISLIVLFHDNDGCTVILVMSLIVASMALMVVAAFTFGKAITEQEFMIKLLVEVIARKPAGKEWGTVAYNMNQYLFMKRLWYTPYYFYSGKKCHEFFTTLIKEVNSGSHSDSSSNSAEDTQSPVSAGKTSNGLNNFYSIRSDPILMAYVLKATQIEKEAQSEYWRKQYPDADLP
What are the official names of this protein?
DUP240 protein YAR028W.
What is the protein family that this protein belongs to?
Belongs to the DUP/COS family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ADEC2_OENOB
Sequence: MIKADLKIINGQIYNTFTRQFTAKEVAIVDGKFFQIADKLSDDFKFEDILDLKGSYVIPGLIDSHMHIESSMATPTNFSETAIRFGTTTVIADAHEIANTSGIKGLKRFMDQPSLIDTFFAIPSSVPSTNPELETTGGIIDLEEVKELLADPRIICLGEAMNFKGITSEPNSLIRKIIALCQKKRPRMPLEGHVPNISKEDLAKFIFAGILSDHTQQTPALIKEKIENGMFIQLQKKSLNKENIETIVKNHFYDYSALVTDDTMADDLINGHLNSIIKLAVKCGLPLEWAIYMTTYTPAQHMHFQDRGVIAPGKIADFVVLNNLDGFSIKNVYKRGVPIDKLSIDDEKPFASEEYHSIYVPNRSAKDFTLRVSKDLKKITANVIEIAAKGTFTKAVKKELLVKDGIVDWQKAGLALLAVQERYGKTGQLTLALVSKSINKSGAIATTWAHDHHNLMVLGTNPDSMAIAYDKVASQQGGYLVVKDKEIVANVQLPIAGIISDEPIDIIGHKLKKVRLAMKDLGYVNTNEIMSLSTLSLLVSPSIKVSDKGIFDVKTQTKIPLLLAGEE
What are the official names of this protein?
Adenine deaminase 2, Adenase 2, Adenine aminase 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: RL14_GEMAT
Sequence: MIQQESVVKVADNSGAKRALVIRVLGGTRRRYAGLGDRVIVAVKDALPNGTVKKSDVAKAVVVRTVKETRRKDGSYIRFDENAVVIINDNGEPKATRIFGPVARELREKRYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TF2LX_MIOTA
Sequence: MEAAADRPAETRSRVEKDSRRAKKDSPAKTQSPAQDTSIMLRSNADTGKVLALPEHKKKRKGYLPAESVKILRDWMYKHRFRAYPSEAEKRMLSKKTNLSLSQISNWFINARRRILPDMLQRRGNDPTVGHKTGKDAHATHLQSTDASVPAKSGPRGSDNVQSLPLRSSPKGQMSGEKIPEPGSAPSQKLTMIAQPKKKVKVSNITSSSSPEPVSTEEYADFSSFQLLVDAAVQRAAELELEKNQESNP
What is the function of this protein?
May have a transcription role in testis.
What are the official names of this protein?
Homeobox protein TGIF2LX, TGF-beta-induced transcription factor 2-like protein, TGFB-induced factor 2-like protein, X-linked, TGIF-like on the X.
What is the protein family that this protein belongs to?
Belongs to the TALE/TGIF homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y4317_RHILO
Sequence: MIKWIIILLIVAAAASLLGMPALAGAAATGARILIGIVLVIFLLVVLGIFAVT
What are the official names of this protein?
UPF0391 membrane protein msr4317.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SC22A_MACFA
Sequence: MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTDNYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQGKAPDYDV
What is the function of this protein?
May be involved in vesicle transport between the ER and the Golgi complex.
What are the official names of this protein?
Vesicle-trafficking protein SEC22a, SEC22 vesicle-trafficking protein homolog A.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MACB2_YERPE
Sequence: MTGPQQGKILLRLENVSREFITGEQTVRVLNNINLTLHSGEMVAIVGTSGSGKSTLMNILGCLDKPSAGEYWVAGRIPQYLGSDALAELRREHFGFIFQRYHLLNDLSARENVEIPAIYAGIDREERRKRAVNLLSRIGLAERLDYRPSQLSGGQQQRVSIARALMNGGDVILADEPTGALDTHSGNEVLNILKDLHQQGHTVVIVTHDMSIAEHAQRIIELKDGEIIADRPRDHAQEKPKMVDIPSVIDIPSMDEKISTGAQQETEIARKPLLTRWKVQYDRLHEAFKMAILAMAAQRLRTALTMLGIIIGIASVVSVVALGKGSQQQVLANINAMGTSTLEIFPGKDFGDMRSAAIHTLRDTDADVLAQQGYIHSVTPTVSTSVTLRYGNKSVSGTVNGVGEQYFLVRGYTIAQGMAFTRTSVNDLMQDAVIDENTRDKLFPNGETPLGKVILLGSLPCRVIGVAAKKQSGFGSDENLNVWIPYTTAMKRMLGQSYLKSITVRVNDDIDLANAEQGVIKLLSQRHGTQDFFVMNTDSIRQTIQATTSTMTLLVSMIAVISLIVGGIGVMNIMLVSVTERTKEIGVRMAVGARASDIMQQFLIEAVLVCLLGGSLGVALSLGIGLLFSLFSSNFSMVYSAASIITAFVCSSLIGVIFGFFPAKRAAEMDPIRALERE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSD_BACC2
Sequence: MRRTLYRLMIELTNGRFTSYILRKFAQSRLSSIIIPSYAKVFQINQDEMEKGLKEYRTLHELFTRKLKEGKRSIDTDASSIVSPVDGVFADHGPIEDTKTFDIKGKRYSIVDMLGNEERATRYAGGTYMVIYLSPSHYHRIHSPLSGSVTERFVLGRKSYPVNAAGMEYGKEPLSKNYRSVTEISSDGEHMALVKVGAMFVNSIELLHERDTVQKGEEMAYFTFGSTVVLLFEKDMIEVVQELKSGQELRLGEKIATRLAHK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AZOR4_BACAN
Sequence: MTKVLFVKANNRPAEQAVSVKLYEAFLASYKEAHPNDTVVELDLYKEELPYVGVDMINGTFKAGKGFDLTEEEAKAVAVADKYLNQFLEADKVVFGFPLWNLTIPAVLHTYIDYLNRAGKTFKYTPEGPVGLIGDKKIALLNARGGVYSEGPAAEVEMAVKYVASMMGFFGATNMETVVIEGHNQFPDKAEEIITAGLEEAAKVANKF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 4, Azo-dye reductase 4, FMN-dependent NADH-azo compound oxidoreductase 4, FMN-dependent NADH-azoreductase 4.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RS13_YERPY
Sequence: MARIAGINIPDQKHTVIALTAIFGIGKTRSQAICVAAGIAEHVKISELSEEQIEKLRDEVAKYVVEGDLRREVTLSIKRLMDLGTYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: UVRD_ECOLI
Sequence: MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQSYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFGEGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLESV
What is the function of this protein?
A helicase with DNA-dependent ATPase activity (PubMed:8419285).  Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand.  Initiates unwinding more efficiently from a nicked substrate than ds duplex DNA (PubMed:8419285).  Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair, and probably also in repair of alkylated DNA (Probable).
What are the official names of this protein?
DNA helicase II, DNA 3'-5' helicase II.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: FENR1_SULAC
Sequence: MVIIGGGPIGLYATFYAGLRDMRALVIDAQDELGGQLVTLYPEKVVYDVGGYPGILAYDLAQNLIEQAKMFSPDIRINEWADMIERTPDNMWIIKTDKGGAFKTKTILIAAGIGKIIPSRLNAKGEIEYENKGVYYTVRRKRDFEGKRILIVGGGDSAVDWALTLSPVAKSVTLIHRRDQFRAHERSVKQMFQVATVYTWHELKEVKGDGSKVTQAVIFDNRTKEEKTLDVDAVIISIGHKGDLGNMVKWGLNMKGRSITVNGKMETNLAGVYAAGDIVEQEGTPKLALIATGFAQAAIAVSVAKKYIDPNASVFAGHSSEMDNKFKK
What are the official names of this protein?
Ferredoxin--NADP reductase 1, FNR 1, Fd-NADP(+) reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: IHH_RASPA
Sequence: VMNLWPGVRLRVMEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYAMLARLAVEAGF
What is the function of this protein?
Intercellular signal essential for a variety of patterning events during development.
What are the official names of this protein?
Indian hedgehog protein, IHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Cell membrane. Secreted, extracellular space. Note=Indian hedgehog protein N- product: Cell membrane; Lipid-anchor; Extracellular side. The N- terminal peptide remains associated with the cell surface. Indian hedgehog protein C-product: Secreted, extracellular space. The C- terminal peptide diffuses from the cell.
Protein: SDHD_ECO24
Sequence: MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMNQYLAKGR
What are the official names of this protein?
D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: NCAP_KHUV
Sequence: MDADRIVFKVKNQLVSVKPEVIVDQYEYKYPAIVDRQKPSITLGKAPDLNKAYKSILSGLTAAKLDPDDVCSYLAAAMELFDGTCPDDWTSYGILIAKKGDKITPATLVNIQRTDVEGNWALTGGLDLTRDPTVAEHASLVGLLLSLYRLSKVSGQNTGNYKTNVADRMEQIFETAPFAKIVEHHTLMTTHKMCANWSTIPNFRFLAGTYDMFFSRIEHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAKEAILYFFHKNFEEEIKRMFEPGQETAVPHSYFIHFRSLGLSGKSPYSSNAVGHVFNLIHFVGCYMGQIRSLNATVISSCAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELKEYEAAESVKTDTALADDGTVNSDDEDFFSGETRSPEAVYTRIMMNGGRLKKSHIRRYVSVSSNHQARPNSFAEFLNKTYSSDPR
What is the function of this protein?
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: HPDA_CLOD6
Sequence: MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANPESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECVNSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKCHEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENISNLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWTQLGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF
What is the function of this protein?
Catalyzes activation of 4-hydroxyphenylacetate decarboxylase under anaerobic conditions by generation of an organic free radical on a glycine residue, via a homolytic cleavage of S-adenosyl-L-methionine (SAM).
What are the official names of this protein?
4-hydroxyphenylacetate decarboxylase activating enzyme, Hpd-AE.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
Protein: ENV_EIAV2
Sequence: MVSIAFYGGIPGGISTPITQQSEKSKCEENTMFQPYCYNNDSKNSMAESKEARDQEMNLKEESKEEKRRNDWWKIGMFLLCLAGTTGGILWWYEGLPQQHYIGLVAIGGRLNGSGQSNAIECWGSFPGCRPFENYFSYETNRSMHMDNNTATLLEAYHREITFIYKSSCTDSDHCQEYQCKKVNLSSSDSSNSVRVEDVMNTTEYWGFKWLECNQTENFKTILVPENEMVNINDTDTWIPKGCNETWARVKRCPIDILYGIHPIRLCVQPPFFLVQEKGIANTSRIGNCGPTIFLGVLQDNKGVVRGDYTACNVSRLKIDRKDYTGIYQVPIFYTCTFTNITSCNNESIISVIMYETNQVQYLLCNNNNSNNYNCVVQSFGVIGQAHLELPRPNKRIRNQSFNQYNCSINNKTELETWKLVNTSGITPLPISSEANTGLIRHKRDFGISAIVAAIVAATAIAASATMSYVALTEVNKIMEVQNHTFEVENSTLNGMDLIERQIKILYAMILQTHADVQLLKERQQVEETFNLIGCIERTHVFCHTGHPWNMSWGHLNESTQWDDWVSKMEDLNQEILTILHGARNNLAQSMITFNTPDSIAQFGKDLWSHIGNWIPGLGASIIKYIVMFLLIYLLLTSSPKILRALWKVTSGAGSSGSRYLKKKFYHKHASREDTWDQAQHNIHLAGVTGGSGDKYCKQKYSRNDWNGESEEYNRRPKSWVKSIETFGESYISEKTKGEISQPGAAINEHKNGSGRNNPHQGSLDLEIRSEGGNIYDCCIKAQEGTLAIPCCGFPLWLFWGLVIIVGRIAGYGLRGLAVIIRICIRGLNLIFEIIRKMLDYIGRALNPGTSHVSMPQYV
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N- terminus of Gag (By similarity).
Protein: GSA_CELJU
Sequence: MSRSEELFLQAQKHIPGGVNSPVRAFKAVGGTPVFFEKALGAYIWDADGKRYIDYVQSWGPMVLGHAHPEVINTVIDAAKHGLSFGAPTERETTLAEKLCSLMPGMDMVRFVSSGTEATMSAIRLARAFTKRDKIIKFEGCYHGHSDSLLIKAGSGALTLGVPSSPGVPAVLADHTITLDYNNAEQVRECFAELGEQIACIIVEPVVGNMNCVPPVPGFLECLREVCDRYGSVLILDEVMTGFRVSPTGAQGYYGIKADITTLGKVIGGGMPVGAFGGRRDIMQMIAPSGPVYQAGTLSGNPVAMAAGLKTLELLQAPEIYPHLYARTNQLVEGLQTLADKAGIPFTTNHVGSMFGFFFTEEKKVTNFKQVMACDIPRFNKFFHGMLERGIYLAPASYEAGFMSTAHTQGDIDQTLGAAEAVFSSL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_LISIN
Sequence: MKKIILLGATGSIGTQTLTIIRENPEKFQLVAFSFGRNIERGRAIIQEFKPKMVAVWHTRDRVTLESEFPDVKFFNGLDGLREVATYLDGDVLLNAVMGSVGLLPTLDAIEAGKAIAIANKETLVTAGHLVMQAAKEKNISLLPVDSEHSAILQALNGENRERIEKIILTASGGSFRDKTREQLSEVTVKEALKHPNWNMGNKLTIDSATMFNKGLEVMEAHWLFGVDYDDIEVVIQRESIVHSMVQFVDGSFIAQLGTPDMRMPIQYALTYPDRLSIPYEKEFRITDFSALHFEEVNYERFPALKLAYNAGKIGGTMPTVLNAANEIAVAGFLNGQVAFYNIEALVENAMNRHTSISNPNLDTILQVDQETRAYVKTLL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MLA_CAMDR
Sequence: SYSMEHFRWGKPV
What are the official names of this protein?
Melanotropin alpha, Alpha-MSH.
What is the protein family that this protein belongs to?
Belongs to the POMC family.
What are the subcellular locations of this protein?
Secreted.
Protein: NADK_AZOVD
Sequence: MEHFRNIGIIGRLGSTQVVDTIRRLKRFLLDRHLHVILDEGIAELLPGHGLQVSSRKQLGEVCDMVVVVGGDGSMLGAARALARYKVPVLGINRGSLGFLTDIRPDELETRVAEVLDGQYTVESRFLLETQVRRKLEPIGQGDALNDVVLHPGKSTRMIEFELYIDGQFVCSQKSDGLIVSTPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHTLSSRPIVVAGNSELKIVVSPKMDIYPQVSCDGQNHFTCSPGDIVTISKKPQRLQLIHPLDHNYYEVCRTKLGWGSRLGGGS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_THENN
Sequence: MKTSDYLKKYGIRLKKHLGQVFLSDDRIAKRIVKEADLKPDDVVVEIGAGAGTLTEELAKTGARVIAYEIDEGLAPILQERLSKYPNVELRFEDFLKARDVPEEAICVSNIPYSVTGPIMEKIIEWRFKKAIVMVQKEVGERILSKPGRKSYGYLSVVVQTFYEVRKLFDVSRSYFVPNPEVDSVVVEMKRKAVEIDFPQFKKFVSMIFSKKRKTLKNNLRPFLSVFEGVDLSRRAEQLSIEEIIELYNIWRRALECSEE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_RHIEC
Sequence: MPETEKPLFGHPWIFIRGVPSLNFLPPEGPPEVAFAGRSNVGKSSLINALVSQKGLARTSNTPGRTQELNYFVPDGYSGEAGDLPPMAIVDMPGYGYAQAPKEQVDKWTKLVFDYLRGRATLKRVYVLIDSRHGIKKNDDDVLDLLDKAAVSYQLVLTKTDKIKAPAVPKLLAETADKIRKRPAAYPYLLSTSSEKGDGLDELRQAIAETVGIANWK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RS11_BACLD
Sequence: MAAARKTNTRKRRVKKNIESGIAHIRSTFNNTIVTITDVHGNALSWSSAGALGFKGSKKSTPFAAQMAAETAAKGSIEHGLKTLEVTVKGPGSGREAAIRALQAAGLEVTAIRDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: Y3704_YERPA
Sequence: MNKQPEDWLDDVPENKNDDDDEIIWVSKSEIKRDAEALKDLGTELVDLGKNALERIPLDEDLLAAIELAQKIKKEGRRRQLQLIGKMLRARDVEPIQTALDKLKNRHNQQISLFHKLETLRDRLIAEGDEAIPTVLELYPDADRQQLRSLVRNAQKEQAANKPPKSFRQIFSYLRELAEKKQ
What are the official names of this protein?
UPF0307 protein YPA_3704.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.