PharMolix/UniProtQA huggingface dataset:
Protein: BETB_AGRRK
Sequence: MRAQPKASHFIDGEYVEDTDGTVIESIYPATGEVIARLHAATPAIVEQAIAAAKRAQPEWAAMSPTARGRILKRAADIMRERNRELSELETLDTGKPIQETIVADPTSGADSFEFFGGIAAAGLNGSYIPLGGDFAYTKRVPLGVCVGIGAWNYPQQIACWKGAPALVAGNAMVFKPSENTPLGALKIAEILIEAGLPKGLYNVIQGDRETGPLLINHPDVAKVSLTGSVPTGRKVAAAAAGSLKHVTMELGGKSPLIVFDDADIDSAIGGAMLGNFYSTGQVCSNGTRVFVNRKIKAEFLKRLKARTEAMLIGDPMDEATQVGPMVSWAQREKVLSYIEKGKAEGATLVAGGGIPNNVSGEGYYVQPTVFADVTDDMTIAREEIFGPVMCVLDFDDEAEVIARANDTEFGLSGGVFTADLTRAHRVVDQLEAGTLWINAYNLAPVEIPFGGSKQSGFGRENSLAALEHYSELKTVYVGMGPVQAPY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PGTA_BOVIN
Sequence: MHGRLKVKTSEEQAEAKRLEREQKLKLYQAATQTVFQKRQAGELDESVLELTSQILGANPDFATLWNCRREVLQQLEVQKSPEELATLVKAELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPNWARELELCARFLEVDERNFHCWDYRRFVAAQAAVPPAEELAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPEDVLLKELELVQNAFFTDPNDQSAWFYHRWLLGRADPQDALRCLHVSRDEACLTVSFSRPLLVGSGMETLLLMVDESPLAVEWRTPEGRNRPSHIWLCDLPATSLNDQLPQHTFRVIWTAGDAQKECVLLKGRQEGWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILLMRALDPLQYEKETLQYFQTLKAVDPMRAAYLDDLRSKFLLENSVLKMEYAEVRVLHLGHKDLTVLCHLEQLLLVTHLDLSHNRLRALPPALAALRCLEVLQANDNAIESLDGVTNLPRLQELILCNNRLQQPAVLQPLTSCPRLTLLNLQGNPLCQAEGSSEHLAELLPSVSSILT
What is the function of this protein?
Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.
What are the official names of this protein?
Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type II subunit alpha, Rab geranyl-geranyltransferase subunit alpha, Rab GG transferase alpha, Rab GGTase alpha, Rab geranylgeranyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
Protein: CCR5_HYLML
Sequence: MDYQVSSPTYDIDYYTSGPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKHFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTS_SOLUE
Sequence: MSDASTPLMRQYNSIKEQVPNALLMFRLGDFYELFFEDAVTAARELEITLTARNKEKGNAIPMCGVPYHAAEGYISRLIQKGFRVAICDQVEDAKLAKKLVRREITRVVTPGTAMDSNLVRSRENNFLAAVGRSGSRSAVAHVDVSTGEFRVTEMEPEEVAGALEHLGAREVLFPGDLPLLTGEDRSGLRFVRTELEDWVFTHDYSDRTLRDHFKLLSLDGCGLANRAAAIGAAGAILHYLRDTQRAALDHLDRPTYYDRADSMVLDSVTVRNLELIEPLFAADAGGIHAQPTVLGVLDQTLTGMGGRLLRQRLLRPSMNRAEIEQRLDAVGELQQQTILRAELRKQLSGILDLERLLAKVTLGSAGPRDVLALGRSLEKIPALKRCFDTQQAARLRNLHDRLDELADVASLILDCISDEPPLNLVDGGTIRAGFHPELDELRDLSQNGKQYIAQIEARERQRTGIGSLKVRFNNVFGYYIEITRANQHLAPADYERKQTLANAERFTTPELKDYERKVLDAEDKILTLEKELFSDVRKRAAAHAQRIRAAAAAVAELDVTASLAQVAAENRYQRPCFSDSGEMRIMAGRHPVIERLTEQEAGRFIPNDLYLNDSTDLLAIITGPNMGGKSTYLRQAALIAILAQIGSFVPAESASLPVIDRIFTRIGASDNLARGRSTFMVEMTETAVILNTATPRSFIVLDEVGRGTATYDGLALAWAVVEYIHQRTRAKTLFATHYHELTELAEQLSGVRNLMVSVKEAGDHIIFLRKVEPGKADRSYGIEVARLAGLPISVIERARDVLKLHERTEHAVSGELVKSEDHGPVQIQMFEPVGYGIAERIRAINVDELRPIEALQLLSELQKELKRS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y1152_SYNY3
Sequence: MLSLIKIAAAQTQWPKRDNSKYSRHGVSLSMNINPLLRAYEHGVRRFPRENLQNADLSGFTLISVDFERTNLIGSNLQRTFLTKARLGHCQMNWADLTYAKLNQADLSHADLTKASLYGAFAVKTNFKGAKLSGATLAHANLRGANLEQTNLTGANLFAANLREANFQKADFSWANLQEACLSLANLRDARLWATDLRRAFMKEMDLSALSLHGLAMDGAKLTGSCLRDTNLSHSSLRGANLRGADLTGANLTGVDLTGADLMGANLTQVVWHDAVVEGVNWEEAIADQSMFREGILGLGNHHNHRSHNVHQGRQGLNISCFGGLQAAYVI
What are the official names of this protein?
Uncharacterized protein slr1152.
Protein: PURA_MALP2
Sequence: MNENLLMIIGSQFGDEGKGKFVDLLSNQFDYIVRYQGGDNAGHTIVFDNKTFKLRLIPSGIFNPRNRVVIANGVVLNPITLLEEVKYLKSNGVSTDNLYVSDKCHVIFNFHIEMDKMLEELKGSKKIGTTNKGIGPCYTDKVSRVGIRVCDLFDFNVLLAKIQDNLQIKNVLFSRYGKQIFNPYTIAKQYYELGQQIKPFVINTVALLNYAYERNNKILFEGAQGIMLDIDYGTYPYVTSSNVIGLVSSGTGLAINKIKRILGVVKAYSTRVGSGPFVSEIEEENLAHYIREKGHEYGTVTKRPRRIGWLDLFLLKYVVTVSGISEIAITLIDVLSKVQKIKVCIGYKRNDKQLNYMPSSIEELQKCEPIYEILDGWSEDVSRIKSYDDLPLNLKRYISYIENFLKVRVRFVSVGPDRNQTIIKDN
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRX45_CAEEL
Sequence: MFQILMENVEVQHIDRIAALLIFFTSFIGFACNTFIAFYIRRLSLLRNSFGRLLQLQAAGDAVFVLVWAFYFAPVLFFDIKPLQSLAIAARFAQLCLICYDISIYTHLVISLNRFISLYFPTSYQNIFTERFTTFLICSIIFVSFGFSWFLVIRDCQMGFSIPRWMLDYVSPPCEMINVYYAEFFRGLIVISMFAITNSFTFCRMHMHNRKKQTATVFETTQQKKRRAVETRFVQQVTMQGLLYVIELVTYFYISLRFPVPLEPVELAKSSNRWPNFLLTTYAWILVHALDGVITLIFNKQFRSVLRHPCRSQEALNISKTPSRRSRFTTNRDESNRKKSSILACTFISNSNTGYGSSVHV
What are the official names of this protein?
Serpentine receptor class X 45, Protein srx-45.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPC_SALRD
Sequence: MSILDDIIDDTRELVEQRKQETPTSELKERPFYDEREPLSLAEALKERGLSFIAEVKKASPSKGVIRDPFDPAAIAQQYAEHDAAAISVLTEPLHFEGALEHMAWIRAHVPETPLLRKDFIIDPYQLVEARAVGADAVLLIATALDPGQLAELHAAATELGLSCLVEVYEEEDLDKIDWEQVSVLGVNNRDLHTFEVDLDNSLRIFDQTPKGVGRVAESGLSDPETLVRLRKAGVNGVLIGEHLMRAEHPGEALSRLRAEGKKIAAQQAG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: STRP_STREQ
Sequence: MKNYLSFGMFALLFALTFGTVNSVQAIAGPEWLLDRPSVNNSQLVVSVAGTVEGTNQDISLKFFEIDLTSRPAHGGKTEQGLSPKSKPFATDSGAMSHKLEKADLLKAIQEQLIANVHSNDDYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLSGHVRVRPYKEKPIQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKNHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYRVKNREQAYRINKKSGLNEEINNTDLISEKYYVLKKGEKPYDPFDRSHLKLFTIKYVDVDTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPNDK
What is the function of this protein?
This protein is not a protease, but it activates plasminogen by complexing with it.  As a potential virulence factor, it is thought to prevent the formation of effective fibrin barriers around the site of infection, thereby contributing to the invasiveness of the cells.
What are the official names of this protein?
Streptokinase C.
Protein: PAAG_ECOLI
Sequence: MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYREGVSAFLAKRSPQFTGK
What is the function of this protein?
Catalyzes the reversible conversion of the epoxide to 2-oxepin-2(3H)-ylideneacetyl-CoA (oxepin-CoA).
What are the official names of this protein?
1,2-epoxyphenylacetyl-CoA isomerase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: THIB_ECOLI
Sequence: MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import (PubMed:12175925).  Binds thiamine, thiamine phosphate and thiamine diphosphate with high affinity (PubMed:12182833, PubMed:18177053).
What are the official names of this protein?
Thiamine-binding periplasmic protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DPOL_ADEG1
Sequence: MLIAKNVTGEWVWITSRTPVQQCPTCGRHWVRRHSCNERRSAFYYHAVQGSGSDLWQHVHFSCPAQHPHIRQLYITYDIETYTVFEKKGKRMHPFMLCFMLSGDPQLVSRAERLARQDDRLKALDEGFYWLDSHPGEVARRFRNFRSRLQIEFAQNLVDRYAAANRDYCDQLVKDGKYGSVHKIPYELFEKPTSPLSLPDNFYSVDIVVLGHNICKFDELLLATELVERRDLFPEACKCDRSFMPRVGRLLFNDIIFRMPNPNYVKKDASRVERWSRGIVSHQDARSVFVRFMVRDTLQLTSGAKLSKAAAAYALDLCKGHCPYEAINEFISTGRFHADADGFPVERYWEDPSVIAEQKNLWQKEHPGQQYDIVQACLEYCMQDVRVTQKLAHTLHDSYDAYFQRELGMEGHFNIFVRPTIPSNTHAFWKQLTFSNYVREQRATCPPSVPEPPKKKGRTKKKKQPSPDYVAEVYAPHRPMFKYIRQALRGGRCYPNVLGPYLKPVYVFDICGMYASALTHPMPHGMPLDPKFTAQHVEELNRLLTNESHLSYFDARIKPSILKIEAYPPPPEMLDPLPPICSRRGGRLVWTNEALYDEVVTVIDILTLHNRGWRVQVLHDEMNIVFPEWKTLCADYVTKNILAKEKADREKNEVIRSISKMLSNALYGAFATNMDTTRIIFEQDLSEADKKNIYEGTEIVKHVTLLNDDSFNGTEVTLENAPNPFSEESLRQQFRYADDPEQEEPEAEEDGEEEGDDSDRESARKPKNALTEDDPLVAVDLEVEATLATGPYIPEGELSSAHYARANETRFKPMRLLEATPEALTVLHLESLDKQVANKRYATQIACFVLGWSRAFFSEWCDILYGPDRGVHILRREEPRSLYGDTDSLFVTETGYHRMKSRGAHRIKTESTRLTFDPENPGLYWACDCDIKCKACGSDTYSSETIFLAPKLYGLKNSICVNEQCRTVGPGKIRSKGHRQSELIYDTLLRCWRRHEDVQFGAQSNIPELHTRRTIFKTTLLNKVSRYDPFTIHNEQLTRVLRPWKDLTLYEHGDYLYPYDNEHPNPRTTGDVRPVPIVGHEDPLAPLRWEPYAFLSEEECGQVHDLLFADDSSQEAESLGV
What is the function of this protein?
Eukaryotic-type DNA polymerase involved in viral genomic replication.  DNA synthesis is protein primed, and acts in a strand displacement replication.  Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication.  The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: TX35B_CTEON
Sequence: GKCGDINAPCTSACDCCGKSVECDCYWGKECSCRESFFGAATXL
What is the function of this protein?
Insecticidal neurotoxin that reversibly inhibits the N-methyl-D-aspartate (NMDA)-subtype of ionotropic glutamate receptor (GRIN) and inhibits inactivation of insect sodium channels (Nav).  In vivo, is highly toxic to insects.
What are the official names of this protein?
U9-ctenitoxin-Co1a, U9-CNTX-Co1a, Neurotoxin Oc FU-18.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 05 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACDH4_RHOOB
Sequence: MSRKSAAIIGSGNIGTDLMYKLLRSEHVEPRFMVGIDPGSEGLARARQEGLEASAGGLDWLLAQPELPDIVFEATSAKIHAAAAPRYAAAGITAIDLTPASVGPYVVPAVNLDAHLGAPNVNMVSCAGQATIPILYAINEVADASYGEIVAAIASHSAGPGTRQNLSEFSEKTGKALAQVAGADRAKAISVINPAEPPMNMRDTVYAKVRNPDPAAIEKAVIDMVAKVQQYVPGYSLRLVDVDGDLVTVMLEVVGAGDFLPTYAGNLDIITAAAVQVADVMAQQNLVQGAAQ
What are the official names of this protein?
Acetaldehyde dehydrogenase 4, Acetaldehyde dehydrogenase [acetylating] 4.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RBL_MALDO
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RFCL_HALLT
Sequence: MADWTEKYRPSTLSEVRGNDKARDAFADWARSWDDHHEAVVLHGSPGVGKTSAAHALANDMGWETVELNASDQRTADVIERFAGRAARNATLGGSAAGGGAAGGDTASRQLVILDEADNIHGNYDRGGASAITELVKESGQPIVLIANDYYDMARGLRNATQEIEFRDVSARSIVPVLRDICRKEGIEFESDALERIAERNRGDLRGAINDLQAATEGRDSIAVEDVVTGDRDKALGLFPYLDAVLKEESAEEALQSAYAVDETPDDLTKWIENNVLDVYDPSEVVRAYDFLANADVWLGRVRATQNYSYWRYATDNAAAGVAAARDGTKGGWTRYGRPQFWSPSDATADEVVGQIAAKSGCSVATARREVLPFLEAVTHHCKPRELTVAMAAAYDLDEAGIAFVTGSGESTNKVASIAEDAQALREERMEDHAEGAFAGGRHAADDLGASDGETTNASGTASSSGDDGDADGTTDGDGSDANDGNDDDDDGQAGLSDFV
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: RL21_PYRAE
Sequence: MVKRTHGYRYKTRKLLRKKPREKGLSGLSRLLYEYKVGDKVIIDIDSTFISTAPHRRYQGKVGTVVGIRGRAYVIETFLGDKKKIIITTPEHLKPYQGGS
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: RS17E_HALWD
Sequence: MAIKPKYVKQLGTLLLEEYPQAFNTDFETNKESVETLTNVESKGVRNRIAGYITRKKGSNTPPSASA
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: CY550_NOSP7
Sequence: MFRRLIGVVVATVLLSFQLLVGSATAVELDKATRTVPLNAEGETTVLSLKQVKEGKRLFNYACAQCHAGGVTKTNQNVGLTPEDLALATPNRNNIEGLVDYLKNPTTYDGEEEISEIHPSIKSADIFTAMRNLTDEDLEAIAGHILIQPKIVGTKWGGGKIYY
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550, Low-potential cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: ARGR_ESCF3
Sequence: MRSSAKQEELVRAFKALLKEEKFSSQGEIVVALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPASGFSVKELYEAILELFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTDB_ECOL6
Sequence: MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELKRPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGKGGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEFGPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK
What are the official names of this protein?
L(+)-tartrate dehydratase subunit beta, L-TTD beta.
What is the protein family that this protein belongs to?
Belongs to the class-I fumarase family.
Protein: TRPF_SYMTH
Sequence: MWVKICGLQFMKDAVAAVEAGADALGFVFAPSRRQVTPERVEALISGLPPETVTVGVFVDAPMEEIRRAVTLSGLKAVQLHGSEPPEAIDQIGLPVIKAIRIRGPEDLARLPDYRNAAGLLLEPYVEGQAGGTGQTLDPTLVRWAAQTLERAGVPLAGPDEPLTPGRPKLILAGGLTPDNVADAIARAQPGGVDVSSGVENGGVKDINKIYAFVAAAKGVAR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: SYC_CLOTE
Sequence: MKLYNTLTRQKEEFIPLKTGEVNMYVCGPTVYNFFHIGNGRTFIVFDTVRRYLEYKGYKVKFVQNFTDIDDKMIKRANDEGITVKELGERFIGEYYKDADSLNIERATVNPRATEFMEEIIQFVKELVDKGYAYEIDGDVYFHTKRFNEYGKLSGQNIEDLQAGARINVDERKKDAMDFAIWKKQKPGEPAWESPWGMGRPGWHIECSCMAHNLLGDTIDIHAGGHDLIFPHHENEIAQSECRTGKPFAKYWMHSAFLNIDNKKMSKSLNNFFTAREILEKYDADVVRLFMLSAHYRAQLNFSEELLQSAMSAVERLYNAIYNLENLANEVKRNDLNEEEKKYIKKLDEYREKYIEKMDDDFNTADAIAVIFDMIRDINSNVKSDSSKKIIEYALSIIRELGSPLGILQKSTEESVEDEIQQLIDRREKARTEKNWALADEIRDGLKERGILLEDTPQGVRWKRI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_RICBR
Sequence: MSSNKINKKSIARIAAIQAIYQHMLRNNDNIDDIIENVLSFYRNDTSMTDSPIKISLTISHFKMLVKLVFENIDKIDEIISNHLVNDKNQNHIPILLQALLRSGICELLFFPDIPTKVIINEYTDIANDMLNDHEIGFVNSILDKIAHENKRFYDK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NDOR1_YARLI
Sequence: MSFLLNLIPAISHTNHDEMHEPNQTHLHRHADTSPTNQHNTSHKMTTTEPIHVTTGSGESRDHTEPRHVTPTSPNALDGRRITIAYATETGNAQDFATLLGNACTRLRFESHVVQMNDLSPETLAQDVSVLVIVCSTTGQGEIPLNGKKLWKFLLRKKLPPNLLSHVTFTTFGLGDSSYPRFNWAIRKIHKRLSQLGASEVGSRGECDDMSPDSIETMYNEWQARFCESLLKAFPLPEGVEVIPGEKLLPAKFPVKVLTNKPKRDTSDADHVACTRKDVLQGTVVGNERVTAKGHFQDVRFFQIDANTEDNDMADLSRDFSKLNSDSRDLHDVSRAVSAGSSIDFSTGDTVSLFPQNSVADVDLLLRDQGWEDIADYKLDAPSLPPIEGGYVTPLTLRSLITHHLDIMGIPRQSFFTYVFHFATSERQKERLQEFSQPGEGLEDLFDYANRPRRSILEVVTEFDSLKIPLKYVLDVFPLMRPRLFSISQKAHTMPIQLCVAIVKYQTIIKRIREGVLTRWLGGLAIGQKIVFTKHSTPIPDLDNYDVIMVAPGTGVAPMRSLILSRESEKETVLFFGNRFREKDFLFQADLEKAVGDKKLNLFTSFSRDENSGGYVQQEMYRQKELVARVLCSKQGVLYVCGSSGKMPREVRITVVTCIQEVNGWTEEQAEEWVKGMEKSGRYLQETW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  Positively controls H(2)O(2)-induced cell death.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: GPR83_MOUSE
Sequence: MKVPPVLLLFLLSSVRATEQPQVVTEHPSMEAALTGPNASSHFWANYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFTIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWVFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWVMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYLLPLFIISVAYARVAKKLWLCNTIGDVTTEQYLALRRKKKTTVKMLVLVVVLFALCWFPLNCYVLLLSSKAIHTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRVELKALLSMCQRPPKPQEDRLPSPVPSFRVAWTEKSHGRRAPLPNHHLPSSQIQSGKTDLSSVEPVVAMS
What is the function of this protein?
G-protein coupled receptor for PEN, a neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N).  Acts through a G(i)- and G(q)-alpha-alpha-mediated pathway in response to PEN (PubMed:27117253).  Plays a role in food intake and body weight regulation (PubMed:23744028).  May contribute to the regulation of anxiety-related behaviors (PubMed:34512237).
What are the official names of this protein?
G-protein coupled receptor 83, Glucocorticoid-induced receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalizes with GPR171 in the paraventricular nucleus (PubMed:27117253). Colocalizes with the ghrelin receptor GHSR1A in the hypothalamus (PubMed:23744028).
Protein: RL22_SHESA
Sequence: MEVLAKHRFARTSAQKARLVADQIRGLPVAKALEILTFSPKKAAVLVKKVLDSAIANAEHNEGADIDELKVGAVFVDEGPTMKRIMPRAKGRADRIMKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: THIG_STRM5
Sequence: MNVQVSPDSLVIAGKTYGSRLLTGTGKFKDLEETRLATEAAGAQIVTVAIRRTNIGQNPGEPNLLDVLPPERFTILPNTAGCYTAEDAVRTCRLARELLDGHNLTKLEVLGDQKSLYPDVVQTLKAAEQLVKDGFEVMVYTSDDPILAKRLEEIGCAAVMPLAAPIGSGLGIQNKYNLLQIIEDAKVPIIVDAGVGTASDAAIAMELGCDGVLMNTAIAGARHPVLMASAMRKAVEAGREAFLAGRIPRKRYASASSPIDGLIG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_BACC1
Sequence: MDKKVTEVVEAFAQPIVEELNLELVDVEYVKEGQDWFLRVFIDSEKGVDIEECGAVSERLSEALDKEDPIPHLYFLDVSSPGAERPLKKEKDFQQAVGKQVAIKTYEPIDGEKMFEGKMLSYDGTTITLLLTIKTRKKEIQIPMDKVANARLAVTF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE1_SHEPC
Sequence: MAKPLTITSSHSHFSLAWRAYFEMTKPKVVALMLLTVLVGMCLAVPTAVPVQPLIAGMFGIALMAGSAAALNHLIDRRIDGMMARTYNRPLPKGRVSAKRALIFAASIGGLGFVVLYVLVNPLTAWLTFASLIGYALVYTAYLKRATSQNIVIGGLAGAMPPLLGWTAVTNQFHGHALLLVIIIFTWTPPHFWALAIHRRAEYAKVDIPMLPVTHGVEFTKTCILLYTVLLAIACLLPVLVGMCGPMYFVCSSLLSSVFIYKAWQLKYRDRDGLAMQVFRFSIYHLMLLFMALLIDHYLWS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 1, Heme B farnesyltransferase 1, Heme O synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.