PharMolix/UniProtQA huggingface dataset:
Protein: PYRE_BIFLD
Sequence: MAETLAHRFTEFLLESNALKFGDFTLKSGRKSPYFINAGAFDDGKKIAALGAFYAEKISQAIVHNTIPRNIDTVFGPAYKGIPLAVSTAIALTAGHNMTVGYTFDRKEKKDHGDGGWMVGTPLTDGMKVLLVDDVMTAGTAVREVIPKLKAEANVEVVGLVLSVDRMEKTKDSDLSAVKAVEAEFGFPVLAIANVREIFDAAAKMKNADSAPLLSHDIQQRAAAYLEEYGA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TRMB_STRU0
Sequence: MRVRKRKGAEEHLENHPEYVIMNPEDIKGHWKEVFGNDHPIHIEVGSGKGGFITGKALQNPEINYIGIDIQLSVLSYALDKVLESNAPNVKLLRVDGSSLTNYFENGEIDLLYLNFSDPWPKTKHEKRRLTYKDFLETYKQILPEHGEIHFKTDNRGLFEYSLASFSQFGMTLKQVWLDLHASDFEGNVMTEYEEKFSKKGQVIYRVEAFF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: MDH_SALEP
Sequence: MKVAVLGAAGGIGQALALLLKNQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQIAKTCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKLPTEVEVPVIGGHSGVTILPLLSQIPGVSFTEQEAAELTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEKGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQHSLDAMLDTLKKDIQLGEDFINK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: RL31_CERS4
Sequence: MKKGIHPDYHMIDVKMTDGTVFQIRSTWGKEGEQMALEIDPLAHPAWTGGTAKLMDTGGRVSKFKNKYAGLGF
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: YJDJ_BACSU
Sequence: MKGIFLVVQLGFSIMVFLFLAAVNWYQGSELVSDRFDWNYTAKLSKLLNGIDAVSSPKQISQLDFFIYSAKHYPVMSALMIISFLYVLAALFLLIYSVKCNKQEIHLDC
What are the official names of this protein?
Uncharacterized protein YjdJ.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KDSR_BOVIN
Sequence: MLLLAAASLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEKHSINDKQVVLCISVDVSQDYSQVENVIKQAQEKLGPVDMLVNCAGMSLSGKFEDLEVSTFERLMSINYLGSVYPSRAVIATMKERRMGRVVFVSSQAGQLGLFGYTAYSSSKFALRGLAEALQMEVKPYNVYVTVAYPPDTDTPGFAKENQTKPLETRLISETTSVCKPEQVAKQIVKDVQGNFNSSIGSDGYMLSSLTCGMAPVTSIMEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQKAKLETVDKTA
What is the function of this protein?
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
What are the official names of this protein?
3-ketodihydrosphingosine reductase, KDS reductase, 3-dehydrosphinganine reductase, Follicular variant translocation protein 1 homolog, FVT-1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TOL1_ARATH
Sequence: MGDNLMDKVTAFGERLKIGGSEVSNKISAGVSSMSFKVKELFQGPNPTDKIVEDATTENLEEPDWDMNLEICDMINQETINSVELIRGIKKRIMMKQPRIQYLALVLLETCVKNCEKAFSEVAAERVLDEMVKLIDDPQTVVNNRNKALMLIEAWGESTSELRYLPVFEETYKSLKARGIRFPGRDNESLAPIFTPARSTPAPELNADLPQHVHEPAHIQYDVPVRSFTAEQTKEAFDIARNSIELLSTVLSSSPQHDALQDDLTTTLVQQCRQSQTTVQRIIETAGENEALLFEALNVNDELVKTLSKYEEMNKPSAPLTSHEPAMIPVAEEPDDSPIHGREESLVRKSSGVRGGFHGGGGSGDDMMDDLDEMIFGKKNGCDSSTNPDHDPKKEQSSSKNDDLIRF
What is the function of this protein?
Might contribute to the loading of the ESCRT machinery.
What are the official names of this protein?
TOM1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TOM1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: GATY_ECO55
Sequence: MCVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: RSMG_STRTD
Sequence: MTPEDFYMALKELGFDLSQKQKDQFQRYFELLVEWNEKINLTAITDKDEVFLKHFYDSLAPVLQGHIKNQSIQLLDIGAGAGFPSLPIKILCPNLDVTIIDSLNRRITFLNFLSDELGLSGVHFYHGRAEDFGQDKAFRAQFDIVTARAVARMQVLSELTIPFLKVGGQLIALKAAAADQELVDARNALNVLFAKPILNENYKLPNGDGRNITIIDKKKETPNKYPRRAGIPNKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFE_KLEP7
Sequence: MAALPDKDKLLRNFSRCANWEEKYLYIIELGQRLAPLSPEEHSVQNIIQGCQSQVWIVMDQDPTGVIALRGDSDAAIVKGLIAVVFILYDRMTAQDITEFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAANIS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_MESHJ
Sequence: MPKYEIMTILDPKAEMAIIDNLLKTVFGDNSTEKLRKLETTNLAYSIRKSKIAQYFLVDLNAPTNLIEEFVRRANITREIWRYLIVNLDSEKGLNKKPKIRERNRKYTLRRDRFDKPNFRGNPKSRFDQQDQQATKNQQNFQQNQQNQASQYRENSRQNQDDFQQVSSNQQNFGQNQQNQSGYHRENNRHNQENMHQNNKNHQNQTSQTQRNRRQYQPIKNPKFNQKEKENYNNKKPQSSN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: DTD_GEOKA
Sequence: MRAVIQRAKEAKVTVGGEVVGAIDAGFVVLLGITHEDTEDDAAYLAEKIAHLRVFEDEDGKMNRSLLDVGGAVLSVSQFTLYGDCRKGRRPNFMAAAKPDHALPLYEAFNAALRERGVHVETGVFGAMMDVSLTNDGPVTLIIDSSEKLGNR
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_RHILO
Sequence: MPKTKKVDRETLPYRPCVGLMILNGEGLVWVGHRIAEPDSEFAGTTQLWQMPQGGIDKGEEPLQAAERELYEETGMRSVSLLAEAPDWINYDLPDHLVGIAFKGRYRGQMQKWFAFRFHGDGSEIQINPPPGGHTAEFDKWSWRPMQDLPDLIVPFKRKVYEEVVAAFSHLAR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: Y244_MYCPB
Sequence: MRKLIKLNVIVFVLLYLGELFASLSFKLISCLKTRNQYSLNGYYALFVFVNIIQKMANSFQKLASSVVLFETEINEFLVLFTDTKNKREESEPVRQVSTTQEYHQVTLDQQHYFNHKLSDYFRLFKDKTFFFEII
What are the official names of this protein?
Uncharacterized protein MPNE_0244.
Protein: S39AD_RAT
Sequence: MPGCPCPGCGMAGQRLLFLTVLALELLERAGGSQPALRSLGAAAACRLDSKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLQSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCNISPGVEGQSLQRQQQLGLWVIAGFLTFLALEKMFLNCKEEDPSQAPSKDPTAAALNGGHCLAQPAAEPGLRAVVRNLKVSGYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWTAAKLQFSTALGGLLGACFAICTQSPKGVEETVVWTLPFTSGGFLYVALVNVLPDLLEEDDPWHLNPPLPTGTPCSRCCCSAPVSW
What is the function of this protein?
Functions as a zinc transporter transporting Zn(2+) from the Golgi apparatus to the cytosol and thus influences the zinc level at least in areas of the cytosol.  May regulate beige adipocyte differentiation.
What are the official names of this protein?
Zinc transporter ZIP13, Solute carrier family 39 member 13, Zrt- and Irt-like protein 13, ZIP-13.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: Y1783_SYNY3
Sequence: MRADFFLSDNRAALLKRGLTIILSFLVFTSIFLLPSPSLAEDVKGADDPIVVAGNIKVKPDKKEEFIALSQTFIEPSRSEPGCISYSFYEDETEDNSFLFFEVWRNRAALDYHFQTPYFHEFVEKSPDLLAKPAEIKIYKIAETQTL
What are the official names of this protein?
Uncharacterized protein sll1783.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
Protein: POLG_PVYC
Sequence: MAIYMSTICFGSIECKLPYSPASCGHVTEEREVLASVEPFMDLEAQLSARLLRQKHATVRVLKNGTCAYRYKTDAQIVRIQKKLERKERDEYHFQMAAPSIVSKITIAGGDPPSKYEPQTPKRVIHTTPRVRKVKKHSIIKLTESQMNHLIKQVKRIMSAKKGSVHLINKKSTHVQYKEILGTTRAAVRTAHMMGLRRRVDFRCDMWTTERLKCLARTDKWSNRVHTINIRKGDSGVILNADSLKGHFGRSSGGLFIVRGSHEGKLYDARSKVTQGVLNSMVQFSNAENFWKGLDDNWARMRYPSDHTCIDGLPVEDCGRVAALMTHSILPCYEITCPTCAQQYANLPASDLFKLLHKHARDGLSRLGSDKDRFVHVNKFLVALEHLTEPVDLNLELFNEIFKSIGEKQQAPFKNLNVLNNFFLKGKENTAHEWQVAQLSLLELARFQKNRTDNIKKGDISFFRNKLSAKANWNLYLSCDNQLDKNANFLWGQREYHAKRFFSNFFEEVDPAKGYSAYEIRKHPNGTRKLSIGNLVVPLDLAEFRQKMKGDYRKQPGVSKRCTSSKDGNYVYPCCCTTLDDGSAIESTFYPPTKKHLVIGNSGDQKYVDLPKGDSEMLYIAKQGYCYINVFLAMLINVSEEDAKDFTKKVRDMCVPKLGTWPTMMDLATTCAQMRIFYPDVHDAELPRILVDHDTQTCHVVDSFGSQTTGYHILKASSVSQLILFANDELESEIKHYRVGGVPNACPELGSTISPFREGGVIMSESAALKLLLKGIFRPKVMRQLLLDEPHLLILSILSPGILMAMYNNGIFELAVRLWINEKQSIAMIASLLSALALRVSAAETLVAQRIIIDAA
What is the function of this protein?
Required for aphid transmission and also has proteolytic activity (By similarity).  Only cleaves a Gly-Gly dipeptide at its own C-terminus (By similarity).  Interacts with virions and aphid stylets (PubMed:9880030).  Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  May have RNA-binding activity (By similarity).
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae genome polyprotein family.
Protein: HIS6_PARDP
Sequence: MLKTRVIPCLDVADGRVVKGVNFVDLRDAGDPVEAARAYDAAGADEICFLDIHATHENRGTMYDLVTRTAEACFVPLTVGGGVRSHQDVRALLLAGADKVSFNSAAVANPDVIAEAADRFGSQCIVCAIDAKTVAPGKWEIFTHGGRKPTGIDAVEFARTVAAKGAGEILLTSMDRDGTKSGFNIPLTRAVADAVTIPVIASGGVGMLEHLAEGVLEGHASAVLAASIFHFGTFTVREAKEHLAAAGIPVRLT
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_EMARV
Sequence: MPIIPKPKSQTKGSVESSKKESRVKMETSDAKYMVGNEVKTIKFLDMRGNIATSARNSLNISPGVFAVNPFLGETLAEDTFNILDYAGLGNVDACASHLSRSQELREQVTEKTLREVPISDSYVLKVVSNLQATTVQNVVSFNKACAVMSFNILRHTTDEMYDWTKNEYVSLGLKEKAAKVNPNIINRLAGQINLSPQSPYYYLVTPGYEFLYDAYPAETIAMTLVKMAYRKTMNLPDSMKDSDICSSLNAKINKRHNLAVNNIDDIIKQIGKKHIEDMYNTLTQNIAMSGKESRNVETAQSFLALIESFKTTT
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TKL4_LOCMI
Sequence: APSLGFHGVR
What is the function of this protein?
Myoactive peptide.  Stimulates the contraction of the oviduct and foregut.
What are the official names of this protein?
Locustatachykinin-4, Locustatachykinin IV, TK-IV.
What are the subcellular locations of this protein?
Secreted.
Protein: MACC1_HUMAN
Sequence: MLITERKHFRSGRIAQSMSEANLIDMEAGKLSKSCNITECQDPDLLHNWPDAFTLRGNNASKVANPFWNQLSASNPFLDDITQLRNNRKRNNISILKEDPFLFCREIENGNSFDSSGDELDVHQLLRQTSSRNSGRSKSVSELLDILDDTAHAHQSIHNSDQILLHDLEWLKNDREAYKMAWLSQRQLARSCLDLNTISQSPGWAQTQLAEVTIACKVNHQGGSVQLPESDITVHVPQGHVAVGEFQEVSLRAFLDPPHMLNHDLSCTVSPLLEIMLGNLNTMEALLLEMKIGAEVRKDPFSQVMTEMVCLHSLGKEGPFKVLSNCYIYKDTIQVKLIDLSQVMYLVVAAQAKALPSPAATIWDYIHKTTSIGIYGPKYIHPSFTVVLTVCGHNYMPGQLTISDIKKGGKNISPVVFQLWGKQSFLLDKPQDLSISIFSCDPDFEVKTEGERKEIKQKQLEAGEVVHQQFLFSLVEHREMHLFDFCVQVEPPNGEPVAQFSITTPDPTPNLKRLSNLPGYLQKKEEIKSAPLSPKILVKYPTFQDKTLNFSNYGVTLKAVLRQSKIDYFLEYFKGDTIALLGEGKVKAIGQSKVKEWYVGVLRGKIGLVHCKNVKVISKEQVMFMSDSVFTTRNLLEQIVLPLKKLTYIYSVVLTLVSEKVYDWKVLADVLGYSHLSLEDFDQIQADKESEKVSYVIKKLKEDCHTERNTRKFLYELIVALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGNTGDVAVEMMWKPAYDFLYTWSAHYGNNYRDVLQDLQSALDRMKNPVTKHWRELTGVLILVNSLEVLRVTAFSTSEEV
What is the function of this protein?
Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling.  Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.
What are the official names of this protein?
Metastasis-associated in colon cancer protein 1, SH3 domain-containing protein 7a5.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly found in the cytoplasm in non-metastasizing tumors.
Protein: CAPSD_BPPH8
Sequence: MSVYTTAQLLAVNEKKFKFDPLFLRIFFRETYPFSTEKVYLSQIPGLVNMALYVSPIVSGKVIRSRGGSTSEFTPGYVKPKHEVNPLMMTLRLPDEDPQNVADPVYRRRRIILQNMKDEELAIAQVEEKQAVSAVLSGKYTMTGEAFEPVEVDMGRSAGNNIVQAGAAAWSTRDKETYDPTDDIEAYALNARGVVNIIVFDPKGWALFRSFKAVEKKLDTRRGSNSELETAVKDLGMAVSYKGMFGDVAIVVYSGQYVENDVKKNYLPDLTMVLGNTQARGLRTYGCILDADAQREGIDASTRYPKNWVQLGDPVREFTMIQSAPLMLLPDPDAFVSVKLA
What is the function of this protein?
Assembles to form an icosahedral capsid with a T=7 symmetry.  The icosahedral capsid is about 60 nm in diameter and composed of 415 major capsid proteins.  The assembly is primed by the interaction between capsid assembly protease and portal dodecamer, and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein.  Major capsid protein forms hexons and pentons of the icosahedron.  Viral genomic DNA is packaged into the procapsid through the portal vertex.  The packaging triggers a dramatic reconfiguration of the capsid shell.
What are the official names of this protein?
Major capsid protein, Gene product 5, Gene product E, Major head protein.
What is the protein family that this protein belongs to?
Belongs to the lambda phage major capsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Forms the capsid icosahedric shell.
Protein: ISPF_IDILO
Sequence: MKIRVGHGYDVHRWGSDKPLILGGVEIEHHQGLVAHSDGDVVLHAVTDAVLGALALGDIGQHFPDTDERYAGADSAELLSHAVSLCQEKEFKTGNIDVTIVAQAPKMAPHIDDMRSSIAQCLKTCIDNVNVKATTTEKLGFVGREEGIACHAVVLMESF
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RL4_CALBD
Sequence: MAKVPVYNIEGQQIGEIELNDSIFNVPINTHVLHQAVVAHLANRRQGTFAAKTRAEVRGGGRKPWRQKGTGRARQGSIRAPTWRKGGVVFAKKPRDFSIDLPKKVKRLALKCALSSKVKENNLIVLDRWDMNQYKTKEVLRVLKNLGLENQKALIVIPEKNEYLQKSTKNIPEVKTLQVGNLNVFDILKYDKFVILQDAVKKVEEVYA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PXDN1_CAEEL
Sequence: MNLYLLLLVIATSSWQFVAGLECPVECTCDKKGLVVDCSSSGLTRIPKNISRNVRSLVIRNNRIHKLKRSDLEGFNQLETLVLTHNKIKIIEENVLDHLPELKRLSLAHNELVYIPPLCSDSRPLASLNLKRNHIQFIDEQVLRYFPDLTQLDFSHNRIQSLRTKLFDNLPALSHAHLHSNPWHCDCRASKVKALLQKVKWEKKVYCTNPVELRHQALDEVDDSALTCARPAEESWTGEEIKLTCAKNSSSKLVVWMYENVEVDSSSLDGYEIHDTVITVPRKTNVNFMTCTYDFDHIPHHRRLRQSQHQGNGSPQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYPFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAGNPVGAMSADAKLTVIGGETRKAAAPQIDEELLRAIAQKARQNVENAVEKTRKQLTQDKVTNTNDLKRLFRFSTPKQAVELSKAREIYEESVRLVREHVEKGLILNVDELHPKNVSYESVLHVTHVQALMGLSGCHTGQYKNPCTDTCFHHRYRSFDGQCNNKNKPMTGVSLMPLRRLLKPVYENGFNTPVGWEKGRLYNGYPLPNVREVSRQLVATENITPHSKLSSMVMQWGQFVDHDLTHTVTALSRHSYATGAFCNRTCENLDPCFNIPLSPNDPRVKSGSAKYPCIEFERSAAVCGSGETSLVFNRVTYREQMNALTSFLDASNVYGSNEVQAQELRDTYNNNGMLRFDITSEAGKEYLPFEKDSNMDCRRNFSEENPIRCFLAGDLRANEQLALAATHTIFIREHNRIAKKLKSMNGNWDGEIIYHETRKIVGAMMQHITYKHWMPIIFGGQAQMNKFVGTYQGYDPDVDASVTNAFATAAFRFGHTIINPSLFRLGNDFMPIKEGHIALHKAFFTPELVLTQGGVDPLLRGLFASPLKHPMPTQLLNMELIEKLFMKGHEVSLDLAVMNIQRSRDHGLPSYTEYRKFCNLPVPVQWEDMKGYIKDDMIIQKLRGLYGVPQNIDLWVGGIVEEKLENGLFGPTFACIIGEQFRKIRDGDRFWYEKDGVFTPEQLREIKKITLARLFCDNGDNIDRIQKDVFMYPGMDKENYGTCQETEMMNLRAWSKCCDNVCPTMLDRILRSRHRGSRLHGCNQNGIWRPEGAKWIPQNEICTECVCQGSRVWCSTKEDCSDNRSPF
What is the function of this protein?
Catalyzes the two-electron oxidation of bromide by hydrogen peroxide and generates hypobromite as a reactive intermediate which mediates the formation of sulfilimine cross-links between methionine and hydroxylysine residues within an uncross-linked collagen IV NC1 hexamer (By similarity).  Plays a role in the attachment of tissues and in axonal guidance during early developmental stages (PubMed:25475546).  May functionally antagonize the peroxidasin pxn-2 to maintain neuronal development (PubMed:20876652, PubMed:26194821).
What are the official names of this protein?
Peroxidasin homolog pxn-1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. XPO subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Localizes to the extracellular space in between body wall muscle cells.
Protein: DHPS_SHIFL
Sequence: MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAEVNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: CSRA_PSEMY
Sequence: MLILTRRVGETLMVGDDVTVTVLGVKGNQVRIGVNAPKEVAVHREEIYQRIQKEKGDEPSH
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_SPHAL
Sequence: MSFNSFGRVLRFTTWGESHGPALGAVVDGCPPRLSLSEADIQPFLDKRRPGQSRHTTQRQEPDQVRILSGVFEGKTTGTPISLMIENVDQRSKDYGEIAQAWRPGHADYAYDAKYGIRDYRGGGRSSARETAARVAAGAVARLVIPEVQIHAWVAEIGGDAIDPANFDLEEIDRNPFFCPDPAAAQRWEALMDSARKAGSSLGAVIECAASGVPAGWGAPVYAKLDSDLAAAMMGINAVKGVEIGAGFGVARLRGEENADPMRPASDGSNRPDFLSNNAGGIAGGISTGQPVVVRVAFKPTSSILTPVPTVNKAGEATDIVTRGRHDPCVGIRGAPVVEAMMALTLADHKLLHRAQCG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PPM1G_HUMAN
Sequence: MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDSETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKKKKAKRD
What are the official names of this protein?
Protein phosphatase 1G, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, PP2C-gamma, Protein phosphatase magnesium-dependent 1 gamma.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor.