PharMolix/UniProtQA huggingface dataset:
Protein: YFBM_ECOLI
Sequence: MGMIGYFAEIDSEKINQLLESTEKPLMDNIHDTLSGLRRLDIDKRWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDGIDGFLGLTWNQELAATIDRLESLDRNELRKQFSIKRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRMLRQGNHALTVIVG
What are the official names of this protein?
Protein YfbM.
Protein: ISPE_ALKCK
Sequence: MKYSIKAPAKINLSLDVIRKREDGYHEVEMIMTMVDLADRVDLSLRADGGISIDVSEGFVPSDERNFAYQAASLLKKRYNVREGVHIYITKRIPVAAGLAGGSSDAAATLKGLNELWQLGLSVDELATLGAEIGSDVSFCVYGGTALATGRGELIKPIASPPPLWVILAKPPIGLSTADVYNGLKLSEARHAKTAEMIAALERQDAASICALLHNTLEDVTLRLYPEVAHIKEQMKRFGANGVLMSGSGPTVFGIVEKESRVNRIYNGLRGFCDEVYAVRLIRTSGTCPNTDENGML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ACKA_MYCA1
Sequence: MDGSDGARRVLVINSGSSSLKFQLVDPESGVAASTGIVERIGEESSPVPDHDAALRRAFDMLAGDGVDLNTAGLVAVGHRVVHGGNTFYRPTVLDDAVIARLHELSELAPLHNPPALLGIEVARRLLPGIAHVAVFDTGFFHDLPPAAATYAIDRELADRWQIRRYGFHGTSHRYVSEQAAAFLDRPLRGLKQIVLHLGNGCSASAIAGTRPLDTSMGLTPLEGLVMGTRSGDIDPSVVSYLCHTAGMGVDDVESMLNHRSGVVGLSGVRDFRRLRELIESGDGAAQLAYSVFTHRLRKYIGAYLAVLGHTDVISFTAGIGENDAAVRRDAVSGMEELGIVLDERRNLPGAKGARQISADDSPITVLVVPTNEELAIARDCVRVLGG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_SYNP6
Sequence: MALLDLTVQMACSDRLPDLPWQDWLDRWLTDIQPQLPEDWQAPTYEACLRFVDDAEIQQLNRDYRQLDKPTDVLAFAALEDELALGFDPEEPLYLGDVIISVPTAQRQAQGHALETELVWLSAHGLLHLLGWDHPNEEQLAAMLTQQERWLQLVAVPVPPRWLDEVSQPPSSEP
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM22_MOUSE
Sequence: MAAALLRELGALRVPNLRIWATQTLRVLPPSCIHTSASLDISRKWEKKNKIVYPPQLPGEPRRPAEIYHCRRQIKYSKDKMWYLAKMIRGMSIDQALAQLEFNDKKGAQIIKEVLLEAQDMAVRDHNVEFRSNLHIAESTSGRGQCLKRIRYHGRGRFGIMEKVYCHYFVKLVEGPPPPPEVPKTAVDHAKDYIQQLRSRTIIHTL
What are the official names of this protein?
39S ribosomal protein L22, mitochondrial, L22mt, MRP-L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GARE1_MOUSE
Sequence: MDPAPSLGCSLKDVKWSPVAMPLDLLVSTYRLPQIARLDSGECVEGLRENDFLLIHSCRQWTTITAHSLEEGHYVIGPKIEIPVHYAGQFKLLEQDRDIKEPVQYFNSVEEVAKAFPERVYVMEEITFNVKVASGECNEDTEVYNITLCTGDELTLMGQAEILYAKTFKEKSRLNTIFKKIGKLNSISKLGKGKMPCLICMNHRTNESISLPFQCKGRFSTRSPLELQMQEGEHTIRNIVEKTRLPVNVTVPSPPPRNPYDLHFIREGHRYKFVNIQTKTVVVCCVLRNNKILPMHFPLHLTVPKFSLPEHQVKGDMWPETLVHHWLGICQEQFDIDEYSRAVRDVKTDWNEDCKSPKKGRCSGHNHLPNSLSYARDELTQSFHRLSVCVYGNNLHGNSEVNLHGCRDLGGEWAPFPHDILPYQDSGDSGSDYLFPEANEESAGIPGKTEVPYEELWLEEGKPSRQPLTRSLSEKSRCDTLRGSTRSTCAPSSPPTPATLGATIKSSEIALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPVRPQTRSPSPTLSYYSSGLHNIITQSDTSPPNSAPVSCYPCTRVKSDSVDPKSPFGSPSAEALSSRLSWPNHYSGASENQTRSDFLLDPSRSYSYPRQKTPGTPKRTCPAPFDFEGCELLGSPPSTTSAEFSSSGVPSCPKSASYCLENSEDNSFAAGMTKQSVSCPALPPRAPKPVEQKATPETSPLPLKIDGAEEDPTAGSLDLSEDQYFVRKGMQDIFSVSYPFSSPLHLQLAPRSCGDGSPWQPPADLSGLSIEEVSKSLRFIGLSEDVIAFFVTEKIDGNLLVQLTEEILSEDFKLSKLQVKKILQFINGWRPKI
What is the function of this protein?
Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases.  Promotes activation of the MAPK/ERK signaling pathway.  Plays a role in the regulation of cell proliferation (By similarity).
What are the official names of this protein?
GRB2-associated and regulator of MAPK protein, GRB2-associated and regulator of MAPK1.
What is the protein family that this protein belongs to?
Belongs to the GAREM family.
Protein: DCST2_HUMAN
Sequence: MPKVMKDVVHPLGGEEPSMARAVVRSVGGFTLGLSLATAYGLLELLVEGHSPWGCLVGTLTLAAFLSLGMGFSRQVRATVLLLLPQAFSRQGRTLLLVAAFGLVLQGPCANTLRNFTRASEAVACGAELALNQTAEVLQRAKQPLVSALNKIKAIARKTKEVADRVRKFFRSIMDGVKHIARALRNVWQWLLHIGDVCNSELGNPYLKCARVFDDAKDSCMMVIPQAYHLCYVLMPFKLALCGLASLVQVFCVIPKYIQPFLRQTIGTPVIQLLNRVRQEFEFNMTATHHFSVDLNASRSLSQVAMDLHEAVSMKLHRVREALALMGFTTPLLLVLLYLQALFYRYCYLNWDHYDNIYITSRFLRMEAVRSTAGLPTVLPLSAHEARRYIPPGSIFLSQWEKFFYILETFNLIRHLLLVLFLVFLDYAVFWVLDLARHQLQGEIVARSPVLVSLTVEGTGYAGNIYRDLVSAFDVLQQGNISILSRRCLLRPSEPDSTGYIVIGVMYGLCFFITLFGSYVSRLRRVICASYYPSREQERISYLYNVLLSRRTNLLAALHRSVRRRAADQGHRSAFLVLASRCPCLGPFVSHFWLHQAYCLGCGQPQDEGDMENTVSCSTPGCQGLYCLTCFRLLDNTCSVCASPLSYQGDLDLELDSSDEEGPQLWLAAAQRKDPEQAWLLQQQLQEVLGRSLSMESTSESSDLDEEKGPQQRKHGQQPLPEAHQPVSILTSPEPHRPPETSSATKGAPTPASEPSVPLSPPSLPDPSHPPPK
What is the function of this protein?
Essential sperm cell-surface protein required for sperm-egg fusion and fertilization.
What are the official names of this protein?
DC-STAMP domain-containing protein 2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VGLL1_HUMAN
Sequence: MEEMKKTAIRLPKGKQKPIKTEWNSRCVLFTYFQGDISSVVDEHFSRALSNIKSPQELTPSSQSEGVMLKNDDSMSPNQWRYSSPWTKPQPEVPVTNRAANCNLHVPGPMAVNQFSPSLARRASVRPGELWHFSSLAGTSSLEPGYSHPFPARHLVPEPQPDGKREPLLSLLQQDRCLARPQESAARENGNPGQIAGSTGLLFNLPPGSVHYKKLYVSRGSASTSLPNETLSELETPGKYSLTPPNHWGHPHRYLQHL
What is the function of this protein?
May act as a specific coactivator for the mammalian TEFs.
What are the official names of this protein?
Transcription cofactor vestigial-like protein 1, Vgl-1, Protein TONDU.
What is the protein family that this protein belongs to?
Belongs to the vestigial family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSPA_TROWT
Sequence: MTTRTLRFYALVGFLVFLDQVTKYLAHAYLARDFIVIPNLFRLTLAKNSGAAFSFGTGFSWLFFLLGIIALIFIGWFLPRTTGSIVFLALLQGGIAGNVFDRLFKPPYFGNGEVVDFLNTPLLSGVVFNIADLFILAGVFGTFLFLKGSK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYI_FRATM
Sequence: MSDYKDTLNLPKTSFSMKGNLANKEPMILNKWEKQGIYKKIREHFAGREKFILHDGPPYANGSIHVGHAVNKILKDIIIKSKTLSGYDAPFTPTWDCHGLPIELQVEKKHGKAGQSISEDDFRKECRKYAKKQVEIQKKDFKRLGVLGDWEQPYLTINFDYEANMIRTLAKIIENGHLSKGFKPVHWCTDCGSALAEAEVEYADKVSPAIDVKFKIKDKDKLAQAFGLDSLNHDAFAIIWTTTPWTLPANQAIAVNNQLNYSLIKIEDFYIILAENLVEQTLKRYAIENAQIIATTTGNKLTGIIAEHPFYSRHVPILHGDHVTDDSGTGLVHTAPTHGVDDFTLGKEHNLSMEIFVKGNGCYSENTKLFAGEFIFKANDRIIELLGEKKRLMNSDKIKHSYPHCWRHKTPLMFRATPQWFISMEKQGLRDKALQAIKETSWAPSWGQARIEGMVKDRPDWCISRQRTWGVPLSLFIHKETEELHPNTIEILYKVAEKIEKDGIEAWFNADDCEFITETAQYKSVKDTLDVWFDSGSSSMCILDLDKRLSYPADLYLEGSDQHRGWFQTSLLVAMSAKGSQPYKEVFTHGFVVDEHGRKMSKSLGNVTSPQDIYNTLGADILRLWTASTDYKSEMAVSDQILKRTADTYRRLRNTARFLLSNLDGFNPVTDIIEFDKLVKLDQWAIAKTKEFQDKIIEAYDKYQTHTVAQLIHHFCSIEMGSFYLDIIKDRQYTAKTDGHPRKSAQTAIYHIVHALVRWMAPILSFTADEIWDATLKTTDLPIQLCEWYTGLKSFDQDAELDLEYWAKIQEIRSEVNRVLEIKRNEDVIKASLEAEITIYADKYNYKLLEKLGNELRFLLISSKADLKVIEESTSSSIAANIPGLLIEITKIEEPKCERCWHRSSTVGDNPQYKDICSRCVENITTEAGESREFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIKA_RAT
Sequence: MSESVGRTSAMHRLQVVLGHLAGRPESSSALQAAPCSATFPQASASDVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSNRGNPGNISSRLLESDKARDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQALYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMCIGTGMGAAAVFEYPGN
What is the function of this protein?
Responsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs) (PubMed:9325339).  Plays an important role in fatty acid peroxisomal beta-oxidation (PubMed:9325339).  Catalyzes the cleavage of short, medium, long, and very long straight chain 3-oxoacyl-CoAs (PubMed:9325339).  Medium chain straight 3-oxoacyl-CoAs are preferred substrates (PubMed:9325339).
What are the official names of this protein?
3-ketoacyl-CoA thiolase A, peroxisomal, Acetyl-CoA C-myristoyltransferase, Acetyl-CoA acyltransferase A, Beta-ketothiolase A, Peroxisomal 3-oxoacyl-CoA thiolase A, Thiolase A.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: FANCC_MOUSE
Sequence: MAQESADLASDCQSWLQKLSAWEQASSEETQKDTCLHLSGFQEFLRQMYEILKEMDSDAILERFPTIGQLLAKACWNPLILAYDESQKIVIWCLCCLMNKEPRTSAESGLNSWIRGLLSHVLSAFRFDMKEVCLFTKSLGYESIDYYPSLLKNMVLSLVSELRESHLNGLSTQSRMAPERMMSLSEVCVPLVTLPDMEPLVEALLTYHGHEPQEVLAPEFFEAVNEAFLSEKIVLPTSSVVSLWFRHLPSLEKATLHLFEKLFSSKIICLRRMECCIRESFLPQAACQPAIFRIVDEMFRFVLLETDGAPEVLAALQVFTSCLVEALKKENKQLTFALRTYFPYGAPCLAAALSQHPEAIPQGHRLQPLLHISQLLREAVEDCTRGSPRNPFESWFLFVHFGGWVDLAVAELLLREEAEPPAGLLWLLVFYYSPQDGSQQREQSMVELKVLINRLLMLLRSGPLSATDLQEAAESPSGDPRPPVCGQLVRRLLLSLLLWTPEGHAIVWEAVTHGPTFEITGPGCCPRIWRSTRPQHRPRAHLCCTEMAHTDAVIHEIIGFLDQTLYRSQHLCVEASRKLARDLLKELQAQV
What is the function of this protein?
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function.  May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1 (By similarity).
What are the official names of this protein?
Fanconi anemia group C protein homolog, Protein FACC.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
Protein: TUSB_BUCAT
Sequence: MLHTLMKSPFETNVSLVISMLKKSDDFLALQDGVLIALKDNIFLKSIIMSPVKLYLIKEDVYARGIRKNISREFILINYIHFVSLTLKHKKQMTW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_LEGPL
Sequence: MNNKTNWVIIGRFGRPHGIKGFVTVHSFTDPADNILRYNDWHVFLNKQWQPLKLLTIEVRSKAIIAQIEGYPERELVSALTNLDIGVQESQLAALAPGEYYWYQLIGMSVINSKGDLFGKVVEIMPTGSNDVLVVEGEKRHLIPYLPGQFVINIDESQQVITVDWDMNF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEP1_BACAM
Sequence: MKSEKEKTSKKSAVLDWAKAIIIAVVLAVLIRNFLFAPYVVDGESMEPTLHDRERIFVNMTVKYISDFKRGQIVVLNGENEHYVKRIIGLPGDTVQMKNDQLYINGKKVSEPYLAANKKKAKQDGYTLTDDFGPVKVPDDKYFVMGDNRRNSMDSRNGLGLFTKKQIAGTSKFVFFPFNEIRKTK
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: SPSS_METKA
Sequence: MNLDRYRNIVRETERKYINVNPIQRGGVLTPEARKALLEFGDGYSVCDFCEGLLHEIEKPPIRQFHEDLAEFLGMDVVRITAGARYAKEAVMSALCEEGDVVVADSLAHYTTFVAAEKAGATVREVPNTGHPEYKVKVDEYARVIDEVEDERGDPPALALLTHVDSEYGNLADAEKFVKICRKKGVPALLNCAYTMGRMDLSNLSPKPDFMVGSGHKGMAACAPCGVLAMREEWEEEVLRGSSLRGDVSGREWPHKEVEMLGCTVMGAPIVTMMASFPHVVERVKRWKEEVRKTRWFVKEMERIEGVRQLGERPKRHDLVKFETPGFHEVAEDHPRRGYFLYEELKKRGVIGIQPGQTETIKASVYGLTDEQVEHVVRAFHEIAEEYGLEVS
What is the function of this protein?
Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
What are the official names of this protein?
O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Sep-tRNA:Cys-tRNA synthase, SepCysS.
What is the protein family that this protein belongs to?
Belongs to the SepCysS family.
Protein: ZAPD_ECO27
Sequence: MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFFRNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVLISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIASLNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGHKSRFAIRFMPLDSENGQVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: YHFL_SHIFL
Sequence: MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISISKIIGGCGPTAQ
What are the official names of this protein?
Uncharacterized protein YhfL.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KTHY_HALH5
Sequence: MTKGCFITVEGGEGAGKTSALDAIEEMLRENGLSVVRTREPGGIPIAEQIRSIILDVDHTRMDPRTEALLYAAARRQHLVEKVLPALEAGHVVLCDRFIDSSLAYQGYARGIGFEDILAINEFAIEGRYPDLTLLFRVDPDVGLSRIHRDQSREQNRLDQEALTFHQKVKEGYERIVETYPERVVEIDANQSFDQVVADAVRMIKQRLSL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: MAEL_XENTR
Sequence: MPNKKAARNAYFFFALDMIPELRRRGLQVSGVREAIPLCSEDWALLSADQKEAYAEKARLLKNDPDSTSTYNDGVFGQRKRNATKSSDFSSVGFFQLNDQRNCVTQRTVPAMNIDISFNKNKAPDQHVCYFINIFSHGDMPSLCEQRYVPCEIACVRYSLREGILGSFHDFIDPGELPRGFRYHCQSGSASTHQIPISGFELANSDYHNMFRKLCSFVCPTPCPVVPVYTKANDIYRVDWCLQWLANKAGMENHFRVQEVETLIIKFYQDKLQEEPSRPTVSRLLDVVQWDYSSNTRCKWHEDNDMWCCALASCKKIAYCISKALASVYGVTLTPAHLPNPERSRNQNSVNPKVVVLDAKRFQRVCSSDPKYSTDKSERSSFEPRGVKPYQGPSGGGRGILRLLETLAASQNSSG
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process.  Required for the localization of germ-cell factors to the meiotic nuage (By similarity).
What are the official names of this protein?
Protein maelstrom homolog.
What is the protein family that this protein belongs to?
Belongs to the maelstrom family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to piP-bodies, a subset of the nuage which contains secondary piRNAs (By similarity).
Protein: LPXK_RICRO
Sequence: MIKLLYPEFWQKRNIIAYLLLPISLIYQFLGYLRASLARPIMLPAKVICVGNCSVGGTGKTQIVMYLAKLLKARNVSFVIVTKAYGSNLKSATTIHQGHTALEVGDEGVILAKYGAVIATKNIKEIVPLINELKPDIIIVDDFLQNPYFHKDFTIVSVDSQRLFGNGFLIPAGPLRQYPNKALDAADLIFLVSSHQDKIPQILTPYVNKLINAQIVPSNNIDKTKNYFAFSGIGNPERFFATLKNYGLNITGYKIFPDHYNYLQADLENLYSLAKEHNAILVTTRKDHVKFNDLNNNIVCLDVELSINHPDLLNEKIFKKA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RECA_RHILW
Sequence: MSQNSLRLVEDKSVDKSKALEAALSQIERSFGKGSIMKLGSNENVVEIETISTGSLGLDIALGVGGLPRGRIIEIYGPESSGKTTLALQTIAEAQKKGGICAFVDAEHALDPVYARKLGVDLQNLLISQPDTGEQALEITDTLVRSGAVDVLVVDSVAALTPRAEIEGEMGDSLPGLQARLMSQALRKLTASISKSNTMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGAVKEREEVIGNQTRVKVVKNKMAPPFKQVEFDIMYGEGVSKTGELVDLGVKAGIVEKSGAWFSYNSQRLGQGRENAKTFLRDNPDLAREIELSLRQNAGLIADRFLQNGGPDPDDGDAAAEM
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUE_ECOLI
Sequence: MRQFIISENTMQKTSFRNHQVKRFSSQRSTRRKPENQPTRVILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRERKSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWREVTD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase E, rRNA pseudouridylate synthase E, rRNA-uridine isomerase E.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: Y268_MYCPN
Sequence: MKVLLWIGYVLSFGLLYLYLVKRAKRAALQLNNKLVESHTIPFAVRDFIAACGGRTNFVSLRTSPTQLIVSFAKPELVQIAALQKLGIKGINKSQNQYRFVLGNFVNQLKQQIENER
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
What are the official names of this protein?
Putative phosphotransferase enzyme IIB component MPN_268, Putative PTS system EIIB component.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RSGA2_BACTN
Sequence: MKGLVIKNTGSWYQVKTDDGQFIECKIKGNFRLKGIRSTNPVAVGDRVQIILNQEGTAFINEIEDRKNYIIRRSSNLSKQSHILAANLDQCMLVVTVNYPETSTIFIDRFLASAEAYRVPVKLVFNKVDAYNEDELRYLDALINLYTHIGYPCFKVSAKEGTGVDAIKKDLEGKITLFSGHSGVGKSTLINAILPGTKVKTGEISTYHNKGMHTTTFSEMFSVDGDGYIIDTPGIKGFGTFDMEEEEIGHYFPEIFKVSADCKYGNCTHRHEPGCAVREAVEKHLISESRYTSYLNMLEDKEEGKYRAAY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADE_RALSO
Sequence: MPISPALAERIATSPKAELHIHIEGSLEPELMFALAERNGVKLPYASVDEVRAAYAFNDLQSFLDLYYAGASVLLTEQDFYDMTAAYVARAVADNVRHAEIFFDPQTHTARDVPMHVVIGGIVRALDDAERAHGFSSRLILCFLRHLSEADAFDTLEAALPYIQDPANRIIGVGLDSSERGNPPEKFARVFARCKALGLRLVAHAGEEGPAQYVIDALDILQVERIDHGVRAIDDAALVKRLAASRVALTVCPLSNEKLKVYPDLRDHSLKQLLDAGCAVTLHSDDPAYFGGYMNTNWLATFNALGLSAADAHTLARNSFEASFLPEQDKALWLNAVDIHWRAHT
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: MUTL_STRP3
Sequence: MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITVEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKYMKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTTKKMLAISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYFGTVDNSVKVEKAELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLTRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: METK_SALTI
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLNTSTKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPAEQLILLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGRENFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.