PharMolix/UniProtQA huggingface dataset:
Protein: SYA_SHEPC
Sequence: MYQTTAELRSAFLEFFRSHGHQVVDSSSLVPGNDPTLLFTNAGMNQFKDVFLGMDKRNYTRATTAQRCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEEAICFGWSFLTETLKLPKERLCVTIYQTDDEAFEIWNKKIGVAAENIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGRPGSPEEDGDRFIEIWNIVFMQYNRHISGEMLPLPKPSVDTGMGIERIAAIMQGVHSNYEIDIFRALIAKAAEIIGVTDLSNKSLRVIADHIRSCAFLVADGVMPSNEGRGYVLRRIIRRAVRHGNKLGATEAFFYKLVPTLIDVMGDAAKGLAETQVIVEKALKAEEEQFARTLERGLGILDAALSELTGDTLDGETVFKLYDTYGFPMDLTADVCRERNIIVDEAGFEAAMAEQRSRAQAAGNFGADYNAALKIDAETAFCGYTELVGQAKVTAIYQNGESVTAIKAGDEAVLVLDVTPFYAESGGQVGDKGQLVANGIEFTVNDTQKYGQATGHQGVLVAGSLSIGQMVEAKVDKKLRHRTQLNHSVTHLLHAALRQVLGTHVTQKGSLVDPERLRFDFSHFEAVKPAELKKVEELVNTQIRRNHELKVAEMAIDEAKEKGAMALFGEKYDAQVRVVTMGDFSIELCGGTHVGRTGDIGLFKITSEGGIAAGVRRIEAVTGAAAMAYVAQQQAELEEAAALLKGDTHSVVAKLKAQLDKMKQLEKDMAQLKDKLAAAASADLVGDAVVVNGVNVLIKKLDGVEAGSLRGLQDELKQKLKSAIIVLGTAQEGKVNLIAGVSNDLVGKVKAGELVAMVAAQVGGKGGGRPDMAQAGGSQPENLDAALAQVLPWITERLA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y445_STRSY
Sequence: MKLPKEGDFITIQSYKHDGEIHRTWRDTMVLKTTENAIIGVNNHTLVTENDGRRWVTREPAIVYFHKKYWFNIIAMIRENGVSYYCNLASPYVLDNEALKYIDYDLDVKVFADGEKRLLDVDEYERHRKAMKYSDDIDFILKENVKILVDWINNQRGPFSPAYVNIWYKRYLELRSR
What are the official names of this protein?
UPF0374 protein SSU05_0445.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: PRMA_EXIS2
Sequence: MKWSEVCVHTTQEAIEAVSNILHEAGASGVVIEDVEDFEMMSHREDNFGEIWDEKKRDEYPDSGVLVKAYLAESSDLTDTIKGIERDIQMLTKFGLTIGAGTVTLTQVDEEDWAHSWKQFYKPVKISRHLTVVPMWEEYTPQPDEKIIELDPGMAFGTGTHPTTVLCIQAIENYLQDNDRVVDVGTGSGVLAIAAAKLGAKDVFALDLDEVAVRSATDNVALNKVSQQVTVRQGDLMKELKEPVELIVANILAEVILLFVNDAYELTLPGGHFIASGIIGQKKEMVRDAMVAAGFTIVETTKLEDWVAIIAKREA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_AMMHA
Sequence: MTNIRKTHPLIKIVNHSFIDLPTPSNISAWWNFGSLLGLCLAIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYFTIKDILGVLLLILALMILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPLLHMSKQRSMIFRPLSQCMFWILVADLFTLTWIGGQPVEYPFIIIGQLASVLYFSIILLIMPATSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CLPP_HAMD5
Sequence: MSSFDEQNTRLPSMTLVPMVVEQTSRGERAYDIYSRMLKERVIFLTGQVEEHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFITPDVSTICIGQACSMGAFLLAAGAKSKRYCLPNARVMIHQPLGGFQGQASDIEIHAKEILKVKKRMNDLMAIHTKKTLKIIEKDTERDHFLSAEEAKKYGLVDCVLTERKDVKNFSKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACAD9_MOUSE
Sequence: MSGCVLLSRGATAAAAAARASRVLREFTARRRPLHTSLQSCSFAKELFLGNIEQKGVFPFPEVSQHELSEINQFVGPLEKFFTEEVDSRKIDQEGKIPVDTLEKLKSLGLFGIQVPEEYGGLGLSNTMYARLGEIISLDASITVTLAAHQAIGLKGIILVGNEEQKAKYLPKLSSGEHIAAFCLTEPASGSDAASIQTRATLSEDKKYFILNGSKVWITNGGLANIFTVFAKTEVVDSDGSKTDKMTAFIVERDFGGITNGKPEDKLGIRGSNTCEVHFENTRVPVENVLGEVGGGFKVAMNILNSGRFSMGSAVAGMLKKLIELTAEYACTRKQFNRNLSEFGLIQEKFALMAQKAYVMESMAYLTSGMLDQPGFPDCSIEAAMVKVFSSEAAWQCVSEALQILGGSGYMKDYPYERMLRDARILLIFEGTNEILRLFIALTGLQHAGRILTSRIKELKSGNVTTVMETIGRKLRDSLGRTVDLGLTGDLGVVHPSLGDSANKLEENVHYFGRTVETLLLRFGKNIVEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANMFCVEAYFQNLFSLSQLDKNAPENLDEQIKKVSRQILEKRAYICAHPLDRAS
What is the function of this protein?
As part of the MCIA complex, primarily participates in the assembly of the mitochondrial complex I and therefore plays a role in oxidative phosphorylation.  This moonlighting protein has also a dehydrogenase activity toward a broad range of substrates with greater specificity for long-chain unsaturated acyl-CoAs.  However, in vivo, it does not seem to play a primary role in fatty acid oxidation.  In addition, the function in complex I assembly is independent of the dehydrogenase activity of the protein.
What are the official names of this protein?
Complex I assembly factor ACAD9, mitochondrial, Acyl-CoA dehydrogenase family member 9, ACAD-9.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=Essentially associated with membranes.
Protein: NUOH_PSEP1
Sequence: MSWFTPEVIDVILTVLRAIVVLLAVVVCGALLSFVERRLLGWWQDRYGPNRVGPFGMFQIAADMLKMFFKEDWNPPFVDRVIFTLAPVVAMSALLIAFVVIPITPTWGVADLNIGLLFFFAMAGLSVYAVLFAGWSSNNKYALLGSLRASAQTVSYEVFLGLALMGVVVQVGSFNMRDIVEYQAQNLWFIIPQFFGFCTFFIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFVGEYIGIILISALLVTLFFGGWHGPFGILPQLSFLWFALKTAFFIMLFILLRASIPRPRYDQVMDFSWKFCLPLTLINLLVTAAIVLYNTPAVAAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYE_HALS3
Sequence: MDDELRERVRRAAERAALFNALKHGSDAQVGAIMGPMMGEHPDFRAHGDEIPGVIAPVIEDVNGMSDDEQRARLAELAPEDVEELDSEDEGDDHALPALPNAEAYDEVRMRCAPNPNGPWHVGHARMPSVIGTYKQRYDGSFVVRFDDTDPETKRPDLDAYDQILEDLSYLGFEADEVLTASDRVETYYEHARRLIGMGGAYTCSCPGAEFSDLKNSGEACPHRDKDPETVADEFEAMVDGEYNSGEMVLRVKTDITHKNPALRDWVAFRMVDTPHPRDAASGYRCWPMLDFQSGVDDHRTGVTHIIRGIDLQDSAKRQRFLYEYFGWEYPEVVHWGHVQLDAYDVAMSTSTIKERIAAGELEGWDDPRAPTMQSIRRRGIRGAAVVDAMVELGTSSSDVELAMSAVYANNRDLVDDTAPRQFLVRDGFEARGEGPEESHEAVEVPVDDGPDEATPQVHPEHPDRGDREIPVGERVLVEATDLPAAGDRVWLKGYGPVRYDGERFAFLDADIDIVREEGVDVVQWVPAEHNVDVRLRTMDGDVTGYAEPGFADRDADEIVQFVRVGFARVDAHRDGGASVAYFTHP
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG8_DROVI
Sequence: MSYKNYYTWKYPDIPEHVAPLLLELQNSLVIVGIIGRSKCAQANKMSAFGMQPDKTHEPADGQILCYYKPGTNMLLLHFETTHDEAVLGQQLLKQTSVDFDSFYEQMRSRFLRMLLLALHVCHILVYVETAQTFDTTLVTICQLLKYVREKHVLDFLPQMLRETAAGSLLSDRARLCTPRVLFLFENYPQDEEKSRERISAYEFQTEDKIYELLRQYNIVTNNANNSLFALPNNKQFVFYNAHEKLRPDQLLLAIEALNATMYKSDSKEEEEDTEILELAPFEGFVKPYGAGYEARESDEQLYRKKHTVWHFLQRHVQDALQGCFDEGSFKQLPQSAQFQLLGVNDWHICMDTIHRLLIGNIQEVSYVTNNQNYKAYLRDFNESLNYEKKFWGHLCDLGLKKGISAYKSSAPAIYGSVTHRQLLADAILAFEEEGRGPYAELALAKLSEICLRHWHDGRQQCEQLSLRGNPCTQPKDAPHDKHSSGIVHISSCNCGRTQGRREDPFTLRQANYDYYEHMAAMCNLCVKVKKFQLPVFTPSISDYRAAAFEAAFPLLLQAAKNRTEIATGGDSDLEAAGELYSQPINATEQAPQKPQITLSNGCSQPALSATYGSDLNMSIAGFGASLNEGEEVRSPEISSQIASSGLSSRSNSTSSGTSSANTANELVLQLKERTDQNAANAAVSEICPEALPIVASTEQVSTTEYLPGLVHMSSGCELLPLFPSWSLACVGPSSIYSHNTGLQEHFQSGFLSGANFLLPWDVHVRLVQPHKHPQQQQQSMGKKSQRYRKHGDRLALKIFVGFEYECSRGHRFMMCSPDRVLRGGADIERDTSSKVVNNNMPLYFPCPCRAQPTYLAQLMRIHVVTPKAPVNIILDPKMCVGKYTFTLGCPTLPRLSQSAYWILRLPYVYQGDNVLITPPERLEPDDNMASGCLLAGMFGIAETDTNETNQQAITPLTFTRL
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Probable component of kinase complex containing nonC and recruited to stalled ribosomes (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG8, Protein smg-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG8 family.
Protein: THIO_PENCH
Sequence: MGVTPIKSVAEYKEKVTDATGPVVVDFHATWCGPCKAIAPALEKLSETHTGIQFYKVDVDELSEVAASNGVSAMPTFHFYKGGERNEEVKGANPAAIQAGVKAILE
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: HSCB_RICFE
Sequence: MQNYFQLLGLPQDYNIDLKILEKQYFAMQVKYHPDKAKTLQEKEQNLITAAELNNAYSTLKDTLKRAEYMLLLQNINLNDEKTRSLLSPLELCIFWDEMEIIENTILFSDLEKIKDKYELMKKLEIDSLKQAFEEQNLSDTIIKTSKLKYIGTLLHKLQEKIKSCK
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: SYFB_MYCTU
Sequence: MRLPYSWLREVVAVGASGWDVTPGELEQTLLRIGHEVEEVIPLGPVDGPVTVGRVADIEELTGYKKPIRACAVDIGDRQYREIICGATNFAVGDLVVVALPGATLPGGFTISARKAYGRNSDGMICSAAELNLGADHSGILVLPPGAAEPGADGAGVLGLDDVVFHLAITPDRGYCMSVRGLARELACAYDLDFVDPASNSRVPPLPIEGPAWPLTVQPETGVRRFALRPVIGIDPAAVSPWWLQRRLLLCGIRATCPAVDVTNYVMLELGHPMHAHDRNRISGTLGVRFARSGETAVTLDGIERKLDTADVLIVDDAATAAIGGVMGAASTEVRADSTDVLLEAAIWDPAAVSRTQRRLHLPSEAARRYERTVDPAISVAALDRCARLLADIAGGEVSPTLTDWRGDPPCDDWSPPPIRMGVDVPDRIAGVAYPQGTTARRLAQIGAVVTHDGDTLTVTPPSWRPDLRQPADLVEEVLRLEGLEVIPSVLPPAPAGRGLTAGQQRRRTIGRSLALSGYVEILPTPFLPAGVFDLWGLEADDSRRMTTRVLNPLEADRPQLATTLLPALLEALVRNVSRGLVDVALFAIAQVVQPTEQTRGVGLIPVDRRPTDDEIAMLDASLPRQPQHVAAVLAGLREPRGPWGPGRPVEAADAFEAVRIIARASRVDVTLRPAQYLPWHPGRCAQVFVGESSVGHAGQLHPAVIERSGLPKGTCAVELNLDAIPCSAPLPAPRVSPYPAVFQDVSLVVAADIPAQAVADAVRAGAGDLLEDIALFDVFTGPQIGEHRKSLTFALRFRAPDRTLTEDDASAARDAAVQSAAERVGAVLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_CYTH3
Sequence: MKRIKIKELLSNSSQYIDQQVVLKGWVRTKRGNKHVAFVALNDGSTIHTIQIVLDVAKFNEEQLKDVTTGACISISGKVVTSQGAGQSIEVQGDTLEVIGVADPETYPLQKKGHSLEFLREIAHLRPRTNTFSCVLRLRHAMAFAVHSFFNEKGFVYVHTPIITGSDAEGAGAMFQVTTLDLKNPSKTKEGEVDFTKDFFGKATNLTVSGQLEGELAAMALGEVYTFGPTFRAENSNTTRHLAEFWMIEPEMAFYEIQDNMDLAEEFLKYLVKYALDNCIDDLNFLNEMYDKELIERLKSVVETPFVRLNYTEAVDILIATKQKFEYKVEWGIDLQSEHERYLVEKHFKKPVILTNYPKAIKAFYMKANEDGKTVRAMDVLFPGIGEIIGGSQREDNLEKLQERCKEVGIHENDIWWYLETRKFGSAPHSGFGLGFERLMLFVTGMGNIRDVIPFPRTPQSAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRG1_BOVIN
Sequence: MSSTLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQVIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKVPHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNLIKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK
What is the function of this protein?
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP.  Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions.  When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation.  Binds to microtubules and promotes microtubule polymerization and bundling that are required for mitotic spindle assembly during prophase to anaphase transition.  GTPase activity is not necessary for these microtubule-related functions.
What are the official names of this protein?
Developmentally-regulated GTP-binding protein 1, DRG-1, Neural precursor cell expressed developmentally down-regulated protein 3, NEDD-3, Translation factor GTPase DRG1, TRAFAC GTPase DRG1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The DRG1-ZC3H15/DFRP1 complex associates with polysomes.
Protein: EFG1_BURL3
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRLRLKANPVPVVVPIGAEEGFKGVVDLIKMKAIIWDEASQGTKFDYVDIPAELVDTCNEWREKMVEAAAESNEDLMNKYLEAGELSEAEIVKGLRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVTGELENGEKTERRASDDEKFSALAFKIMTDPFVGQLIFFRVYSGVVNSGDTLLNATKDKKERLGRILQMHANQREEIKEVRAGDIAAAVGLKEATTGDTLCDPAHPIVLERMIFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEATVGKPQVAYRETIRKSAADVEGKFVKQSGGRGQYGHAVITLERSELGKGYEFVDAIKGGVIPREYIPSVDKGIQETLKSGVLAGFPVVDVKVTLTFGSYHDVDSNENAFRMAGSMAFKEAMRRADPVLLEPMMAVEVETPEDFMGNVMGDLSGRRGIIQGMDDMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPKNVAEAIISAKTK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMC_HAEI8
Sequence: MIDCRYYQQNECRSCQWLEIPYSQQLAEKQHHLKQQLISINCDKAQWLAPFQSNEQCFRNKAKMLVSGSVERPILGILKNPNDPQSAIDLCDCPLYPARFSIIFSILKDFIGRAGLVPYNIAKQKGELKYILLTESIATGKLMLRFVLRTENKLPLIRRELPKLLEKLPHLEVVSVNLQPLHAAILEGEQEIFLTEQQFLPENFNSIPLFIRPQGFFQTNPKVAEGLYATAQQWVSELPIYNLWDLFCGVGGFGLHCAKALQEKWGKPIKLTGIEISSSAILAASHSAKILGLEHVNFQSLDAASVIENKNENKPDLVIVNPPRRGIGKELSEFLNQIQPHFILYSSCNAMTMGKDLQHLTCYKPLKIQLFDMFPQTSHYEVLVLLERKKIN
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: KDPB_STAAE
Sequence: MHHVNKYFNQTMVIEALKMSFYKLNLKQLIKNPIMFVVEVGMILTLILICFPDIFGTSYLSRGYLITIFIILLITILFANFSEAFAEGRGKAQADSLRQAQSNLTARLIEENGAYRIVNATELKAGQNIRVENGETIPADGVVINGLATVDESAITGESAPVIKESGGDFDGVIGGTLVTSDWLEIRVESEAGTSFLDKMIALVEGAERNKTPNEIALFTLLTTLTIIFLVVIVTLYPIASYLHLILPIAMLIALTVCLIPTTIGGLLSAIGIAGMDRVTQFNVLAKSGRAVEVCGDVDVMILDKTGTITYGNRIASEFLPVNQQMLEKLIVAAYMSSIYDDTPEGKSIVRLAKQMYINELPKDIDGTYKPFTAETRMSGIITNEISVFKGAPNSMINLVKQQQGNIPLNIESLCMDVSSKGGTPLIVIENNVMLGVIYLKDVIKDGLVERFTELRKMGIETVMCTGDNALTAATIAKEAGVDRFVAECKPEDKIKVIKDEQAKGHIVAMTGDGTNDAPALAQANIGLAMNSGTISAKEAANLIDLDSNPTKLIEVVKIGKQLLMTRGALTTFSLANDVAKYFAILPALMMSTIPEMTSLNIMHLSSPKSAIISALIFNALIIVALIPIAMKGVKVKGYSIDRIFINNMLIYGLGGLIVPFLGIKLIDMIVQFFV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YQ72_SCHPO
Sequence: MDWKEAIPGAAKVAIETKDYITYSTLLELILEEARIKDIDEQRELIKCLHEELKQEKNDHITREISWDIIGMVLPYVGKVQNEADEFVDFLAKNGNPREVFLKCCELLINGGFESPQQFISLNSAILSALHRISTKRPVLFVNNFLISLFSGLANILQIDSDELYCVWKISISSIQDAMHRFPVSECYLACLKACSILAQLFLSKETLMLSFRSLLQTKDQYAEFREELSGATTNCDKLDTLSKSIINIFDYLLSHLPESWSIITEHMAQELTKATYVSQSSSISSEDEEIAKNADVPAEVDNNSTKADDKRDEIEFDTKGCLALLTIKSFYQSGNFFLDFLKEKFPSTILETLQQLVSWEIQLDSVGFKDIAVYQGYLLDLPHFQVPDSELEHLSSLLHGYHFMASSTELPWLRVTCNAIVTKCLDSQLPSVRLSYILDTLEECPLLNIKTAILNYYQKQCSLVKDSNEEGLKNFVSPNTLLDVFKVFDAMEDVELDSQSLSYIHQTLVFLYSLEIQNLLSQNQFPTVYFTKISDQINNYEGELPTDGLKYYIELLNSRNK
What are the official names of this protein?
UPF0649 protein C1442.02.
What is the protein family that this protein belongs to?
Belongs to the UPF0649 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: T2EA_DICDI
Sequence: MSSSNNIYHILDDLVKMVIRAFYPDEYAVIIDGLLREKKRIKDEDLALRLRIQQKYVRKILMDLKGDSMVKSSDVKVEAKGPNERGSTHLLWYIDYKHIIDIVKYKLYMFRKKMESVKVQKIDVQTYKCQTCHKVYTALDIPKLLNMDTGALACEICDGELEEELNNESLTQTAKHQSDLFSQLRKIIEQLKKTEGHNIPLFARDLADLSADQGPSYTINTNSSLGMGPKPSAFPVAQGAATSHHIDPTNENIEFHVDILDTDGIEINKAVVKKENKKTGLASLPPWLLPSNSFKNRNVKSNSILNNNQQTQTSTNEQPTAVKEQIKIDQDFYINYIKTHYQEWESAPDSGDADGNGSNSGSGGSTIEGNDGGNGEHQNKKMKLDDSQTVSSMSQSDDDGKDILVRVGDNLIPITKITEHDQELMSNQEYEDYSHALYSYASKNVFDHQYQSLMSN
What is the function of this protein?
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH.  Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity).
What are the official names of this protein?
General transcription factor IIE subunit 1, Transcription initiation factor IIE subunit alpha, TFIIE-alpha.
What is the protein family that this protein belongs to?
Belongs to the TFIIE alpha subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPE_AZOSB
Sequence: MSLPDTPTLALACELISRSSVTPEDAGCLQLIAQRLAPLGFVCERIDIGGVSNLWARRGSARPLLCFAGHTDVVPTGPLDAWQSPPFEPTIRDGHLYGRGAADMKSSLAGFVTAIERFVAAHPDHAGSIALLLTSDEEGVATCGTVKVVEALAARGERLDYCVVGEPTSVKTLGDMIKNGRRGSLSGTLRVKGRQGHVAYPHLARNPIHELAPALAELAAERWDDGNEFFPPTTWQVSNIHAGTGANNVIPGVCDVLFNFRFGSVSTADALKARTHAILDRHGLDYELDWHLSGKPFITGRGQLVAALGNAIRETVGVETELSTTGGTSDGRFIADICAEVVEFGPVNASIHQVNEHIAVDAVEPLSKIYERTLRALLTA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: FKBP6_BOVIN
Sequence: MSSSRPLNGLSRLDAEDRSPYQRLSQRMLDISGDRGVLKDVIREGAGELVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNTTVLFEIELLDFLDSAESDKFCALSAEQQSQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLHRRTAPPEEQHLVETAKLLVFLNLSFTYLKLERPTMALRYGEQALIIDRKNAKALFRCGQACLLMTEYQKARDFLVRAQREQPFNHDINNELKKLASYYRDYMDKEREMCHRMFASGDNGSTVGEN
What is the function of this protein?
Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.  Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis.  May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity).
What are the official names of this protein?
Inactive peptidyl-prolyl cis-trans isomerase FKBP6, Inactive PPIase FKBP6, 36 kDa FK506-binding protein, FK506-binding protein 6, FKBP-6, Immunophilin FKBP36.
What is the protein family that this protein belongs to?
Belongs to the FKBP6 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Chromosome. Note=Does not localize to pi- bodies. Localizes to meiotic chromosome cores and regions of homologous chromosome synapsis (By similarity).
Protein: METK_LACJO
Sequence: MKKEKRLFTSESVSEGHPDKVADQISDAILDAILAKDPDGRVACETTVTTGLVLVVGEISTSAYVDIQSVVRKTILEIGYNRPELGFDGNNCAILVDIDEQSSDIADGVNESLETRENQQDKDDLDKIGAGDQGLMFGFAIKETPELMPLPISLAHSLMRRVASLRKEGRLDWLRPDAKAQVTVEYDDENKPKRIDTVVISTQTDATVSNDEIREAMIDMVIKKVIPSQYLDKDTKFLINPSGRFVIGGPKGDSGLTGRKIIVDTYGGYARHGGGAFSGKDLTKVDRSASYAARYVAKNIVAAGLAYQCEIQLAYAIGVAHPVSIMVDTHGTSKVSEDLLVEAVRNVFDLRPAGIIEMLNLKRPIYRQTAAYGHFGRTDVDLPWEHTDKVEALKTYVSEHAE
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.