PharMolix/UniProtQA huggingface dataset:
Protein: OVCH2_RHIAE
Sequence: MAETSVFSIMMLTVMTAVGRGATDRPGRVSRCGERPSANASVTYNLLSRIVGGTSAVKGESPWMVSLKRDGKHFCGGTIISDKHVLTAAHCVLDKNIEYHVRVSIGDHDFTVYERSEQIFAIKAVFKHPNFNPIRPFNYDLAIVELGESIAFDKDIQPACLPSPDDVFPTGTLCIALGWGRLQENGRLPSSLQQVVLPLIEYRKCLSIMETVDRRLAFETVVCAGFPEGGKDACQGDSGGPFLCQRSQGRWVLVGVTSWGLGCARKWVDNILDPPERRGSPGVFTDIQRLLNWLSANLNQDKPDFPTYEVQCSTNDGIEKGTAGEILLPTDYRKYYSNNEKCIWTIIVPKGKHILLTFNSFNVEWDYSCDLDYLVIYSALGRLIGKFCGDVRPRPLLIADASVTLKFISDFQEYKTGFSLFYQAVEPNTYPDSDCGSVAVIFEEGEIQTMNHPHVYSSHANCQWVVHSPANHIIKITFLVFEVEPSEGCIFDRLVVYHDLQGTMVAGIFCGFSLPDPVLSVSNVMQITFTSDYSVNYLGFQAVISFVLPSSPVKSETQWKGNNQPRKNQDAMQHYEEGCGVSPLPPRFIHHNIIKAEEAMPNSWPWHVSINFGNKHLCNGAILSKTFVVTSANCVADREEFPSVGLIVAGLHDLESSTDAQKRTVEYVIVHPDYNRLSKDYDVALIHVQMPFQYNSHVQPICLPDGHSKLEPSKLCVVSGWDLNVELSTKLQQLEVPVLMDDVCKKYYDGITDRMFCAGVIAEEDNVSCLAQSGAPLVCQSDPGTYVIFGIVSWGVGCNEPPKAGVYSSVPLFIPWIMETILSVAGIANTDTEPHHPLIPPDKLSQEKALLPDSPPSNDSSSSQDIYVTCKDVMSLQSPGEIKLVASAQDGPEGGRCQLIFQAPEDHFILLHFKQLSHEHYSLIIYEGASSNKTFKAQLTEEKIPTIMKSVGPVITIEASSTAQDSALHLWLSYSFHNQN
What is the function of this protein?
Mediates gamete interaction by affecting the vitelline coat.
What are the official names of this protein?
Ovochymase-2, Oviductal protease, Oviductin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NRX2A_MOUSE
Sequence: MALGSRWQPPPQLPPLLLLLALAAGVRGLEFGGGPGQWARYARWAGAASTGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGAAADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAGRGGAGDVHQPTKGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGAGVGSHSSTQRADYFAMELLDGYLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGESEVLDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGICREGWNRFVCDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPTAMHTEAEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMRLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGAHTRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTMRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPSSGGPCQAERDDSDCEEPVEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGVPTAFEPRRPPPLRPGVTSAPGFPRLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV
What is the function of this protein?
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.  May mediate intracellular signaling.
What are the official names of this protein?
Neurexin-2, Neurexin II-alpha, Neurexin-2-alpha.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FABZ_NOVAD
Sequence: MSEEQGAATDGVILDYDVRKVMAALPHRYPLLLVDRVASLTLNERIHAVKAVSMNEQFFQGHFPGRPIMPGVLQIEALAQAAGVLAVESLGLAGSGKLVYFMAIEDAKFRNPVEPGVLLDLHVEFTQKRSRVCKFSGKAMIGDKVTCEVNFTAMIADS
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_SHEB5
Sequence: MYQTTAELRSAFLEFFRSNGHQVVDSSSLVPGNDPTLLFTNAGMNQFKDVFLGMDKRNYTRATTAQRCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEEAIRFGWTFLTETLKLPKERLCVTIYQTDDEAFEIWNKKIGVAAENIIRIGDNKGAAYASDNFWQMGDTGPCGPCSEIFYDHGDHIWGGRPGSPEEDGDRFIEIWNIVFMQYNRQASGEMLPLPKPSVDTGMGIERIAAIMQGVHSNYEIDIFRTLIAKAAEIIGVSDLTEKSLRVIADHIRSCAFLIADGVMPSNEGRGYVLRRIIRRAVRHGNKLGATEAFFYKLVPSLIAVMGDAAKGLAETQAIVEKALKAEEEQFARTLERGLGILDTALNELKGTTLDGETVFKLYDTYGFPMDLTADVCRERNIIVDEAGFEVAMAEQRSRAQAAGNFGADYNAALKIDAETAFSGYTELAGQAKITAIYQNGESVTAIKAGDEAVVVLDVTPFYAESGGQVGDKGQLVASGVEFTVNDTQKYGQATGHQGVLATGNLSVGQVVEAKVDKKLRHRTQLNHSVTHLLHAALRQVLGTHVSQKGSLVDPERLRFDFSHFEGVKAAELKEVEELVNTQIRRNHELKTAEMGIDEAKEKGAMALFGEKYDSQVRVVTMGDFSIELCGGTHVGRTGDIGLFKITSEAGIAAGVRRIEAVTGAAAMAYVAQQQAELEEAAALLKGDANSVVAKLKAQLDKMKQLEKEMAQLKDKLAAAASADLVGDAVVVNGVNVLIKKLDGVEASSLRGLQDELKQKLKSAIIVLGTAQEGKVNLIAGVSNDLIGKVKAGELVAMVAAQVGGKGGGRPDMAQAGGSQPENLDAALAQVLPWITERLA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_VIBVY
Sequence: MSNRKQARLEAKQFIDTLSVQPYPNSTKVYVEGSRSDIRVPMREISLADSLVGGTKEAPIFQPNEAVRVYDTSGVYTDPTHQIDLYNGLPKLREEWIAERADTEVLDDVSSVYTKERLEDETLDELRYGNLPRIRRAKAGYCVTQLHYARKGIITPEMEYIALRENMGRAKYQDEVLTQQHAGQSFGANLPKEITPEFVRREVAEGRAIIPSNINHPESEPMIIGRNFLVKVNANIGNSSVTSSIEEEVEKLVWSTRWGGDTVMDLSTGRNIHETREWILRNSPVPIGTVPMYQALEKVNGVAENLTWEVMRDTLIEQAEQGVDYFTIHAGLLLRYIPMTAKRVTGIVSRGGSIIAKWCLAHHQESFLYTHFREICEICAKYDVALSLGDGLRPGSIADANDEAQFAELRTLGELTKIAWEYDVQVIIEGPGHVPMHMIKENMDEQLKHCHEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKTGLITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLSLDPDTARAFHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKGQQGEAGQAIEVKLLDDPLEGMKQKSAEFKASGSELYHPAVSHEEVAEG
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: SYY_COLP3
Sequence: MTDFNQAFAELKRGAEEILVEEELLTKLKTGKPLKIKAGFDPTAPDLHLGHTVLINKLRQFQQLGHEVIFLIGDFTGMIGDPTGKNVTRKALTKEDVLANAETYKEQVFKILDPAKTTVAFNSTWMDKLGAAGMLQLASRQTVARMMERDDFKKRYANGQAIAIHEFMYPLVQGWDSVALEADVELGGTDQKFNLLMGRELQKSEGQRPQTVLMMPLLEGLDGVQKMSKSLGNYIGITDTPTDMFGKIMSISDVLMWRYYELLSFKPLEEIEGYKTEIENGKNPRDVKIDLAKELIARFHDEAAAQAAHDEFINRFQKGALPDDMPELTITTENGEIAIANLLKDAGLVGSTSDAFRMIKQGAAKIDSEKVTDRSLVISAGTTAVYQVGKRKFARITVS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_RHORT
Sequence: MLATDRTTLAQFLVEECRGRAGDDSELLGLLLDVAQACKTISKMTAMGSLAGVHGYNGDVNPQGENQARLDLMSNQAFVRATERTGHAAGLASEEMEEVLGFPESYARGTLLLVFDPLDGSSNIDINGTVGSIFSILPMPRPGEAPQTADFLQSGRQQVAAGYALYGPSTMFVLTIGSGVHGFTLDPLLGDFILTHPSMTVIPESGEFAINSSNSRFWEPPIRAYVDELLAGRSGPRSKDYNMRWIAALVADVHRILLRGGIYLYPRDTKTPDLAGRLRLLYEAAPVAFLMEQAGGRCTTGTRTMLDLVPGSLHERVPLIFGSAVEVERVETLYREPQRREFATPLFNQRGLFRD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP22_BLAGS
Sequence: MGSKTPNDHRRGPNVESSPHAAIDTINPPKHAAASGLLHGPLEGETEDGEDEDDDKTGADLKSVGQLNNSTKKKNKRKKNKKKKKTLLGGLQTTPPRVALSSIFYNQRYPEAEIVGYTTNNDNLQRITAEEFRHLCVVNDMDDEFLNDYRKAAEVHRQVRQYVQTITKPGIAMSQLAQEIEDGVRALTDHQGIETGDALKAGMAFPTGLCLNNIGAHWTPNPGAKEVILQYDDVLKVDFGVHVNGRIVDSAYTMAFNPVYDDLLTAVKAATNTGLKEAGIDARIDCISEAIQEVMESYEVELNRKIIPVKAVRNITGHNILRYKIHGDKQVPFVKTHTNQRMEEGDIFAIETFGSTGKAYLDDDIGIYGYFCDEHASAAGLHHSSAKSLLKTIKDNFGTLVFSRRYLERLGVKSYHLGMRSLVSKGIVQSYAPLVDVPGSYVAQFEHTVLLRPNCKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-2, MAP 2-2, MetAP 2-2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_RHOJR
Sequence: MAKRSKAYLAAAEKIDFDKLYSPLQAAKLAKETSSSKMDATVEVAVRLGVDPRKADQMVRGTVNLPHGTGKTARVIVFAVGEKAAEAEAAGADAVGAEDLIERIQGGWLDFDAAIATPDQMAKVGRIARVLGPRGLMPNPKTGTVTADVTKAVADIKGGKINFRVDKQANLHFVIGKASFDDAKLVENYGAALDEILRAKPSSAKGRYVKKVTVSTTTGPGIPVDPNRTRNLLEDADA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PAC1_CAEEL
Sequence: MEEHHRRLHVKAERASVIGGDIVDGAFGSWALRAARSEHQLKQQSNEDLAQNARISALLGEMRPRMSAMPPNGHQQQYQPQLRRKANTTNIVDVSSQVPSARNAIYGSWQDRHRPTRLYGSQLVSSSSTLPKYDQLYCNTASPLTGNGSTNTIATTGIRREPPEYGNVGRSVSTWQVTNSEHRPSLQAGWLKSSRPLARGALSPAAYFRDLENRHGSGASSPIVGGLSVVAVPITQRHAPTAGLAPISDDISTSKVSLDTENQQLNNEDSDKISGSALSRNTPRQASFMAAMQRHPLKESSTSIESNGGGTNTEEDQTVSATSKEDPSEDTGHDDPEETQEISETPIRRSRNRNASLRNRQSSRSLGGLDFEKLRMGTARVGDSNEATAENGTSSSSSRKNSRDDGLTSSPTTVAGPVFTTSSTSSISTSGEASSTAVAAAAAGSVAATTSRQTSSNSSVDSNHNEAMKMIRRARPKSYVLATSASMNEDVLSSSIIANEQSSSISHDTTTSGRELPSSLMGSTISMEMRSGGASSATTTTTSNSGQQTSRSLNAPHPPATHRLQRFIALFNSSKTSDGSGEHKKSRMKRSRTSLPASRFALPGTILQRDGVARQTWVKHQEIALGKSGKRNNWEDRWAVLCRRSLYLCVESPAYTTEKTIELGSHTRVDVCNAIVDIAYDWLSSSFSKQRHVVRIVTQNRSEHLIELNTESEMLSWISVLQSSSEDGIATGSSVDENELSTTGRHNNNAVSNSSALLHNSQSIASLASSSCSTATTSEFLNSQHTLQQQQQQQTNQKHQQTVNELSAGIVSHLPTSKSFGGLSTTASSTTENAKNRLIMHRYIAKNSQLQSPTANKKMETDPSTVPSSSQTMATTSSSFHHHSSQAGPSRDIENGEAPTATATTPKSGRKWKKSKAAKQGSGGGSSGSSSGSQQQGAAGAPQPVLGVRIADCPTGSCEDHVPMIVQACVCVIETYGMDTVGIYRIPGNTAAVNALKESLSNRGFDSVDLSKVESLDPRWRDVNVVSSLLKMFLRKLPEPLLTDKLYPFFIDANRISTHHNRLHKLRNLLRKLPRPHYDTLRFLIVHLSEITKHSDVNKMECRNLALMFGPSIVRPSDDNMATMVTHMSDQCKIIETLIHYNLWMFDESSTTEDAVPEQHPADGQNPLEPGGYGVGVPTGVSAASFNDMHNLIRKANEDQAAAMMNEGKGQKIKNMLRRNSRRDKSKSKLKIESTAPAAVNPRGWTQPTPSNTSAASVESAFCGNYQERDIDAEIESRQTVSPQMTSGSADGASSTRLDQSPSLESSLGSLPDTSRTEPILGSSGYDDDEAKEAARRKRQEEMYSARRIFIAGAAGAAAAATTTADAEKAAIDALANHSQHLHLASSPAFEVLSEETREKIRRMQKKQSWHDTKELRSGELLKTYSPTKDLTDALSCTSDYSTTSSAPLSTNPPLAVACADQPNSSSDYASSDPSPCARNPSTSPASRPSNLAISPAQLHATSSSGQSHQPMSRSQKIRLRTKLGSRDPARRHTLSDVDTLKEGRLDKLARWFGIRKSSPDVSRDEVSDDEKNHQEAPPLPAAAPPVIVRTSPNELTPVSGDELL
What is the function of this protein?
GTPase-activating protein for members of the Rho subfamily including Rac1, RhoA and cdc42 and other Ras-related subfamilies including let-60 (PubMed:18583611, PubMed:8288633).  Mediates radial (inner-outer) polarity and gastrulation by excluding par-6 from contacted cell surfaces; acts by inactivating cdc42 at inner cell surfaces which limits active cdc42 to outer cell surfaces devoid of cell-cell contacts, where cdc42 can bind and recruit par-6 (PubMed:18583611, PubMed:8288633, PubMed:25938815).  Required for blastomere polarization (PubMed:25938815).
What are the official names of this protein?
GTPase-activating protein pac-1, GTPase-activating protein GAP, CeGAP, Protein par-6-at-contacts.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction. Cell junction, adherens junction. Note=Locates to inner but not outer surfaces of early embryonic somatic (EES) cells (PubMed:18583611). Specifically localizes to cell contacts in hmr-1- dependent and -independent manner in embryos (PubMed:25938815).
Protein: PAX_I49A1
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTRVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKSQEPCAGSPTKVSHRTSPALKTLEPMWMDSSRTAALRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: SMG5_DANRE
Sequence: MSGPSQDSEPEAKVLHIKRLYRAVVETVHKLDIIISGKSSYREVFKPENISLRNKLRELCVKLMFLHPVDYGRKAEELLWRKVYYEVIQVIKTNKKHIHSRSALECAYRTHLIAGVGFFQHLLLYIQSHYQLELQDCIDWTHVTDPLIGRKKPVSATSKEMEWAQMACHRCLVYLGDLARYQNELAGVEAEQLAERFYHQALSVAPHVGMPFNQLGTLAGSKFYNVEATYYYLRCIQSETPFDGAYGNLKRLFDKASKMYHQVKKQEMKKLSPSRQRSKDIKRLLVSFMYLQSLLQPKNSLMETELTSLCQSVLEDFNLVLFYLPLPAHGSQSASEEEEEHDSVGSVLPDSLIFKMVVICLMVVHSLKRGASKQYSASIAFTLALFSHLVNHVNIRLQAELEEGESDVPALRTDNTDDADARDHSSAALSEERTLQNGSLEEDDDEEEEEKENGEDEPKGNGRTVATKKNQEKKRSAEEKQKQKRKFSRLSMLRRRRCAHKEDESDLSEGFESDEEEEEEEEGGGGGLVDGLGAPRVQMNSLGRDTRKGPLPEDGGWESGSEEDEGGTAFDVETDSDMNSQESRSDLEDMEDAENAPQQPQQEENEQPQTSREENATPPVTNGPSVSNDASISSNLQAMSSQLFQAKRCFRLAPTFSNVLLRPATTTPPAPESNPAPVQEITPPTGETPRNTSPEIANGTNDKDPDSNSEGSEHSNHSFHSEKTLSERLEILTNQGLIQVVKVFLDWLRTNTDIILMCAQSSQSLWNRLSVLLNLLPEGSKILETDIGLNKDVTELLSECEHPSLAQTLLLPEDMALRHLPALSIAHRRLDFTSQRPPLTPLDECVVRVCCIRSFGHFLTNLQGNVLHFNPEAGIFTSISQSEQDNLVQQAKAQFRMAEEEARRNRLMRDMAQLRLQLEVSQLEGSLQQPKAQSSMSPYLVPDTAVLCQHLGLLRQLAASGCFIIIIPRTVIDGLDMLKKENSGARDGIRFLETEFRKGNRYIRCQKESGRSFERDKLKRQDTEAWHLYKMVDSCRQLTGSQSSGDEDTAGMVTILTGHSLEELSERSASMKAAVQAVAAAGMELKNIIEFYRQWKEMG
What is the function of this protein?
Plays a role in nonsense-mediated mRNA decay (By similarity).  Does not have RNase activity by itself (By similarity).  Promotes dephosphorylation of UPF1 (By similarity).  Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation (By similarity).  Necessary for TERT activity (By similarity).  Required for normal embryonic development (PubMed:19414594).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG5, EST1-like protein B, SMG-5 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLMM_LACDB
Sequence: MLKYFGTDGVRGEANKVLTPEMAFKLGRMGGYVLTKEKEDGGQARVLVSRDTRISGEMLEHALISGLLSVGIEVLECGVMTTPGLSYLVQAQGADAGVQISASHNPVEDNGIKFFGSNGLKLSDAKEEEIEELIDTKQDMLPRPSAEGLGTVTDFRDGSNKYIQFLENTIPEDLSGIKVVIDGANGAASAFISRLFADLDVDFTTISTHPNGLNINDHCGATHTARLQEEVVKQGAQLGLAFDGDADRCIAVDENGNEVDGDHIMYVIGSYLADHGRLKKDTIVTTVMSNLGFTKALERRGIKNVRTQVGDRYVSEEMRANGYSLGGEQSGHVIISDYHNTGDGMLTGLHLMLVMKKTGKSLTELLADFKEYPQVLVNVPVKDKNSWKNHQAVVDAIDSVEKDMAGNGRVLVRPSGTQELLRVMAEGPTQEITQEYVDRIVKVVTTEMGE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: YCJF_ECOL5
Sequence: MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDEAQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRRQLIGQVKETLQKGKTPSEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THII_GEOTN
Sequence: MKYDRILIRYGEMTTKGKNRNIFVRRLKNNIARKLQAFPRIKIEYMRDRMYILLNGEPHEPIIDKLKTVFGIHSFSLAMKCENDLAAIKETALAAVRQLPYKGKTFKVSARRVDKQFPYRSDELNHEVGAHILRQTEDLTVNVRQPDIDVRIEVRQDGTYVTCHDIFGAGGLPVGTSGKAMLMLSGGIDSPVAGYLAMKRGLEIEAVHFFSPPFTSERAKQKVIDLVRKLTAYGGKIKLHIVPFTEVQQAIYQGVPNEYSLISTRRAMLKITDALRRRQRGLAIVTGESLGQVASQTLESMYVINEVTNTPVLRPLISMDKMEIIEIAKQIDTHDISILPYEDCCTIFTPRAPKTKPKKEKVLQHESQLDLAPLLEKAINETETIVIDEEAGQADEFTALF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHJX_ECOLI
Sequence: MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLDAPVSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSDNLMMLWLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTQLLETVGLEKTFVIWGAIALLMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWMLAVMFLTACMSGLYVIGVAKDIAQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDKIARIRVITIGQVISLVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFGLNNLAKNYGVIYLGFGIGSICGSIIASLFGGFYVTFYVIFALLILSLALSTTIRQPEQKMLREAHGSL
What is the function of this protein?
Part of a nutrient-sensing regulatory network composed of the two-component regulatory systems BtsS/BtsR and YpdA/YpdB, and their respective target proteins, BtsT and YhjX.
What are the official names of this protein?
Uncharacterized MFS-type transporter YhjX.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAY_BACFN
Sequence: MLYYLFEWLHKLNFPGAGMFGYTSFRALMAIILALLISSIWGDKFINLLKRKQITETQRDAKIDPFGVNKVGVPSMGGVIIIVAILIPCLLLGKLHNIYMILMLITTVWLGSLGFADDYIKIFKKDKEGLHGKFKIIGQVGLGLIVGLTLYLSPDVVIRENIEVQKSENEIEVIHGTHDLKSTQTTIPFFKSNNLDYADLVGFMGEHAQTAGWILFVIITIFVVTAVSNGANLNDGMDGMAAGNSAIIGLTLGILAYVSSHIEFAGYLNIMYIPGSEELVIFICAFIGALIGFLWYNAYPAQVFMGDTGSLTIGGIIAVFAIIIHKELLIPILCGIFLVENLSVLLQRFYYKAGKRKGIKQRLFKRAPIHDHFRTSMSLVEPGCSVKFTKPDQLFHESKITVRFWIVTIVLAAITIITLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIE_LACCB
Sequence: MNATDLKLYLVTHRYDDNEATFLAKIAAACENGVTMVQLREKMLSTRAYFELAQRVKLITDRYQIPLIIDDRVDICLAVDAAGVHIGDDELPVAMTRQLIGPDKVLGVSTKTVETAVAAVAAGADYLGVGAIFPTQTKANAPVTPIATLKAITAQVAVPVVAIGGVKEANLGTFKETGIAGVAIVSEIMQAPDIAHKVQALRTKLKAVLPNDR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: HIS2_MYCGI
Sequence: MTQSSNVKTFDALFAELSERARTRPAGSGTVAALDGGVHGIGKKILEEAGEVWLAAEHESDDALAEEISQLLYWTQVLMLARGLSLDDVYGKL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDF6A_DANRE
Sequence: MLTLPFEDPVIMDTQFGANFPRDCVGDLKGNKQEPFEKEETLSHVMDDDDSEKDEDEREDGQDENGLPRRRGPRKKKMTKARVDRVKVRRMEANARERNRMHGLNNALDSLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILSTGKRPDLLTFVQTLCKGLSQPTTNLVAGCLQLNARNFIPDQISGEASFSGRSPYESVYSTYHSPSVVTPSGPSVDAVKPFRSFNYCSSYESFYESVSPECGSPQFEGPLSPPINFNGIFSLKHEEPVEYGKSCHYGTRYCAVPPRASIGQSARGSSDLHFPYDIHLRGQFYPVQDELNTFHN
What is the function of this protein?
Differentiation factor required for neurogenesis.  Acts as an upstream activator of isl1.
What are the official names of this protein?
Neurogenic differentiation factor 6-A, NeuroD6-A, Protein atonal homolog 2-A.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y466_BACMK
Sequence: MSEENQPNYTISQENWSLHRKGYDDQQRHQEKVQEAIKNNLPDLVTEESIVMSNGKDVVKIPIRSLDEYKIRYNYDKNKHVGQGNGDSKVGDVVARDGSGGQKQKGPGKGQGAGDAAGEDYYEAEVSILELEQAFFKELELPNLKRKEIDENRIEHIEFNDIRKTGLWGNIDKKRTMISAYKRNAMRGKASFHPIHQEDLKFRTWNEVLKPDSKAVVLAMMDTSGSMGIWEKYMARSFFFWMTRFLRTKYETVDIEFIAHHTEAKVVTEEEFFSKGESGGTICSSVYKKALELIDNKYSPDRYNIYPFHFSDGDNLTSDNARCVKLVEELMKKCNMFGYGEVNQYNRHSTLMSAYKNIKDENFRYYILKQKADVFHAMKSFFKEESGERMA
What are the official names of this protein?
UPF0229 protein BcerKBAB4_0466.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: RL13_TREDE
Sequence: MKTIFFKEHEAPRSWYLIDAAGKPLGRVAAKTAAMLRGKHKVSFAPHQEIGDYVVIINAEKVAVTGNKAKDKMYYTHSGYVGGLKSINFNGLIAKKPAEPLMIAIKGMLPKGPLGRKLLTNVKVYAGPEHPHQAQNPIAVEV
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MIAA_METRJ
Sequence: MPPDREEAGRRPAAILIAGPTASGKSALAARLAERHGGVVINTDSMQVYADLRRLTARPDPDEEARVPHRLYGHVDGAVNYSAGHFSRDAAALLATLGGRLPVFVGGTGLYFRALEQGFSELPPVPDTVRARVRDAAEGRPTEALHADLARHDPEGAARLRPSDRMRVMRALEIFLATGRPIASFYGDPVPGPLAGRDLRRIFLAPDRAALRERIDARFRTMIAEGALDEVARLRARRLDPMLPVMRAHGVPGLIAHLDGALSLDEAIARGQADTRAYAKRQLTWFRHQMGEAWRWVDPEGATVEDLL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.