PharMolix/UniProtQA huggingface dataset:
Protein: VOSA_MAGO7
Sequence: MSLPSIGSVGSDRMAAYMHGQQVYTGQFGDPNLTPPQAETQMSAQASAQAVGQEPEPDYKLVIRQEPQRARVAQGKEKGTDRKPIDPPPIVQLIRTARSDPAQIYLQSPYYFMACTLIKGSDDDPDPNPNSMLGTLVSSLHKLRDLNNEDGGFFIFGDLSIKIEGVFRLQFTLFQMKDSTCVFLDSATSQPFTVYPQKNFEGMAESTFLTRSFSDQGVRLRVRKDSRAMTTRKRNHQHAEVAKKHSEWDRKQTSAVSRHSSINENDSTPTDTRGLASFAGAGSSGYYDQHRSHYGETYGHDTYYGGARSVKRARHEVSPGQYALPDLPQQAYATRQPSFSDSVASMTMPPVTTAAPSLAGINPMSSHHGYTGSAHPGFAPHRINTQVGGSHLAPQPHSAIGSVNQGYQSPSTHHQPHPHTAHPAGGQAYPSPSPRQSPGTAPNYHYGSHHSQQTPVSLGLETYTSAGVVGMPGPGQLVGTSAPSPHLGQGYRHGMINEPGA
What is the function of this protein?
Component of the VELB-VOSA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity).  The complex binds DNA through the DNA-binding domain of VOSA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity).  Appears dispensable for the development and pathogenicity (PubMed:24632440).
What are the official names of this protein?
Spore development regulator VOSA.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VosA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSRP_SALTI
Sequence: MDNVVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYQQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPGNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLTLPTSLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPCLNSTNYSVEEIATKILDIMGLNRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: REC9_HUMAN
Sequence: MNPSEMQRKAPPRRRRHRNRAPLTHKMNKMVTSEEQMKLPSTKKAEPPTWAQLKKLTQLATKYLENTKVTQTPESMLLAALMIVSMVSAGVPNSSEETATIENGP
What is the function of this protein?
Retroviral replication requires the nuclear export and translation of unspliced, singly-spliced and multiply-spliced derivatives of the initial genomic transcript.  Rec interacts with a highly structured RNA element (RcRE) present in the viral 3'LTR and recruits the cellular nuclear export machinery.  This permits export to the cytoplasm of unspliced genomic or incompletely spliced subgenomic viral transcripts (By similarity).
What are the official names of this protein?
Endogenous retrovirus group K member 9 Rec protein, HERV-K(C6) Rec protein, HERV-K109 Rec protein, HERV-K_6q14.1 provirus Rec protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between the nucleus and the cytoplasm. When in the nucleus, resides in the nucleolus (By similarity).
Protein: RECU_BACC2
Sequence: MTIRYPNGKRYNQASQPQKTPIKTHTYSNRGMSLEEELNETNQYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYFKQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVVAHNGIAFVIIKFTLFDEFYLLDAKHIIAFWNRQNTGGRKSITKEEIEEHGSLLSCGYHPRIDYIRVLDTVYFS
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_RHIL3
Sequence: MDIAPEREDSVDMPARRRWFEDRRVLKRIVLAVLIVLILPYALIVFYLLPFIHPVSTLMLRDLVLLRGYDRQWVSLDNIAPVVVQSVMMSEDGQYCFHGGVDWAEMRMLVEDTLKGQATRGGSTIPMQTAKNLFLWNGRSFVRKALELPLAVTTDFVLSKRRLMEIYLNIAEWGPGIYGIEAAARHHFKVPASKLTRRQASLLAVSLPNPIDRNAGKPGRGLRRLAGVIERRAQGSGDYIKCIYD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PCNP_PONAB
Sequence: MADGKAGEEKPEKSQRAGAAGGPEEEAEKPVKTKTVSSSNGGESSSRSAEKRSAEEEAVDLPTKPTKISKFGFAIGSQTTKKASAISIKLGSSKPKETVPTLAPKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQKLWERNIKSHLGNVHDQDN
What is the function of this protein?
May be involved in cell cycle regulation.
What are the official names of this protein?
PEST proteolytic signal-containing nuclear protein, PCNP, PEST-containing nuclear protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL11_PARPJ
Sequence: MAKKIIGFIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAQTQALEPGLPTPVVITAFADKSFTFVLKTPPATVLIKKAAKIDKGSSKPHTDKVGKITRAQAEDIAKTKMPDLTAADLDAAVRTIAGSARSMGITVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RS20_NEIMF
Sequence: MANSAQARKRARQSVKQRAHNASLRTAFRTAVKKVLKAVEAGDKAAAQAVYQESVKVIDRIADKGVFHKNKAARHKSRLSAKVKALA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PYRG_TRIEI
Sequence: MTKFVFITGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTSMSRLNSVTQGSIYQAVINKERRGDYQGGTVQVIPHITNEIKERIHRVAKNANPDVVITEIGGTVGDIESQPFLEAIRQFRKDVRRNNALYIHVTLVPWIASAGEMKTKPTQHSVKELRSIGIQPDILVCRCDRKLSEGLKEKMSEFCDVPVESVITSQDAQSIYEVPLMLETEGLAVQALELLKMEQRQPNLSHWKTLVNRLYHRDKQDIRTSQGKLSITATVEIAIVGKYIQLSDAYLSVVEALRHAAIAVGVDLNLHLVNAEDVETKGARTYLEKANGIIVPGGFGVRGIDGKIATVEYARINKIPFLGLCLGMQCAVIEWARNIAKLDAAHSFEFDPQTPNPVINLLPEQQDVVDLGGTMRLGLYPCRLQGDTLAFKTYQQEVIYERHRHRYEFNNAYRNLFKETGYIISGTSPDGRLVEIIELPAHPFFIATQFHPEFQSRPSTPHPLFHNFFQAANSQEKCDNLSVNNTEETPDNLVSKSSIPN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NUDK_YERPY
Sequence: MSVKIENIQCELLSKNWFKLHKYTFDLKTDEGTSVQQIREVYDRGNGATILLYNRQQGTVVLIEQFRMPTYVNGNASGMLLEACAGLLDNDSPEACIRREAMEETGYQVDKVQKLFEAYMSPGGVTELVYFFAAEYHPDQKITDEVGVEDEVIEVVELPFHDALAMVADGRIKDGKTIMLLQYAQIHFFPSSLTPQRC
What is the function of this protein?
Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate.
What are the official names of this protein?
GDP-mannose pyrophosphatase, GDP-mannose hydrolase, GDPMK.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudK subfamily.
Protein: RTR1_YEAST
Sequence: MATIEDIKETALIPFQKHRQLSMHEAEVITLEIIGLLCDSECKDEKTLKYLGRFLTPDMYQDLVDERNLNKRCGYPLCGKSPERIRDPFSMNDTTKKFLLENNPYAYLSHYCSKFHFRCSQFYQVQLSDEALFARTGVHLFEDPEQDKHDIDFKVTLFEELLREKASEEDIKSLISGLKKLGLNPDSGTTEKDDTELEDDLSKWLAQIKIVENDNPSILGDFTRED
What is the function of this protein?
RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase that dephosphorylates 'Ser-5' of the CTD and regulates RNA polymerase II during the transition from 'Ser-5' to 'Ser-2' phosphorylation.
What are the official names of this protein?
RNA polymerase II subunit B1 CTD phosphatase RTR1, RNA polymerase II-associated protein 2 homolog RTR1, Regulator of transcription 1.
What is the protein family that this protein belongs to?
Belongs to the RPAP2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles constitutively between the cytoplasm and the nucleus.
Protein: URE2_YERE8
Sequence: MSTKTNSTKATSEKTDSLKTNRGTKSSAGYSEQNTPLGGCILADTPITFNENKPVTKVKVRNTGDRPIQVGSHFHFFEANRALEFDRAAAYGKRLNISSTTAIRFEPGDETEVPLIPFGGKQTLYGFNNLVDGWTGEGVVPNSERPDKLEAIRRAAERGFKSSK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCB_PYRAE
Sequence: MRNIPINKINDYVWEIPPGVKPCQKVPVRIYADSVLLEKMKSDMTLEQGINVGCLPGIYRWSIVLPDAHQGYGFPIGGVAAIDAEEGVISPGGIGYDINCGVRVLRTNLTEEDVRPKLKELVDTIFRLVPPGVGGTGHLRLSPSEFERVLAEGVEWAVQKGYGWAEDMEYIEERGSWKLADPSKVSEKAKARGRDQLGTLGSGNHFLEIQVVDKIYDEKIAKLFGIEREGQVVVMIHTGSRGFGHQVATDYLLIMERKMRQWGLNLPDRELAAAPLKDKVAEDYIKAMASAANFAWTNRHIIMHWVREAFKKVFGSIEKVGLEVVYDVAHNIAKLEEHVVDEKGTVRKVWVHRKGATRAFPPGRSEIPAKYREVGQPVLIPGSMGTASWILVGTHDAMRLTFGTAPHGAGRVLSREAAIRMYPPHKVQEEMAKRGIIVRSAETEVISEEAPWAYKDVDRVVEAAHQVGFAKKVVRQRPIGVVKG
What is the function of this protein?
Essential for tRNA splicing and maturation (PubMed:21209330).  Acts by directly joining spliced tRNA halves to mature-sized tRNAs (PubMed:21209330).  Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends (By similarity).
What are the official names of this protein?
tRNA-splicing ligase RtcB, 3'-phosphate/5'-hydroxy nucleic acid ligase, Archaeal 3'-phosphate RNA splicing ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: Y953_BACC1
Sequence: MTKNIHDVAYELQKAIAENDDFKTLKESYAAVQADAASKNLFDEFRTMQLSLQQKMMQGQEITEEDNQQAQEVVARIQQDAKITKLMETEQRLNVVIGDVNKIIMKPLEELYSAQQQA
What are the official names of this protein?
UPF0342 protein BCE_0953.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: UTH1_YEAST
Sequence: MKLSALLALSASTAVLAAPAVHHSDNHHHNDKRAVVTVTQYVNADGAVVIPAATTATSAAADGKVESVAAATTTLSSTAAAATTSAAASSSSSSSSSSSSSSSVGSGDFEDGTISCSDFPSGQGAVSLDWLGLGGWASIMDMNGNTATSCQDGYYCSYACSPGYAKTQWPSEQPSDGRSVGGLYCKNGKLYRSNTDTNSLCVEGQGSAQAVNKVSGSIAICGTDYPGSENMVVPTVVGAGSSQPINVIKEDSYYQWQGKKTSAQYYVNNAGVSVEDGCIWGTEGSGVGNWAPVVLGAGYTDGITYLSIIPNPNNKEAPNFNIKIVATDGSTVNGACSYENGVYSGSGSDGCTVSVTSGSANFVFY
What is the function of this protein?
Involved in aging, oxidative stress response, and in the regulation of mitochondrial biogenesis.  Inactivation of UTH1 increases life span, leads to higher resistance to heat stress and against hydrogen peroxide, and increases sensitivity to the superoxide radical-generating drug paraquat and to copper.  Also required for the selective autophagic degradation of mitochondria (mitophagy) in response to nitrogen starvation.  Involved in the remodeling of the cell wall during the various phases of yeast culture development and under various environmental conditions and plays a role in septation.  Involved in cell sensitivity to boric acid.
What are the official names of this protein?
Probable secreted beta-glucosidase UTH1, Youth protein 1.
What is the protein family that this protein belongs to?
Belongs to the SUN family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein. Secreted, cell wall. Note=Non-covalently bound to the cell wall (PubMed:11958935).
Protein: IRAP_ECOUT
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLRHPRQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_VIBC3
Sequence: MSKKLLIKTWGCQMNEYDSSKMADLLNAANGYELTEIPEEADVLLLNTCSIREKAQEKVFHQLGRWKTLKDKKPGVVIGVGGCVATQEGDSIRDRAPYVDVIFGPQTLHRLPEMIKQSQTSDAPVMDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCSKYCTYCVVPYTRGEEVSRPMDDVLFEIAQLAEQGVREVNLLGQNVNAYRGATHDGGICSFAELLRLVATIDGIDRIRFTTSHPLEFTDDIIAVYEDTPELVSFLHLPVQSGSDRILTMMKRPHTAIEYKSIIRKLRKARPDIQISSDFIVGFPGETDKDFQDTMKLIRDVDFDMSFSFIFSPRPGTPAADYPCDLSEEVKKERLYELQQQINSQAMRYSRLMLGTEQRILVEGPSKKDLMELRGRTENNRVVNFEGSPDLIGQFVDVKIVDVFPNSLRGELLRTEQEMNLRIATSPSEMKAKTRREDELGVATFTP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDHA_DANRE
Sequence: MASTKEKLIAHVSKEQPAGPTNKVTVVGVGMVGMAAAVSILLKDLTDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDYSVTANSKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCILLVVSNPVDILTYVAWKLSGLPRNRVIGSGTNLDSARFRYLMGEKLGIHPSSCHGWVVGEHGDSSVPVWSGVNVAGVSLQALNPDLGTDKDKEDWKSVHKMVVDSAYEVIKLKGYTSWAIGMSVADLCESILKNMHKCHPVSTLVKGMHGVNEEVFLSVPCILGNNGLTDVVHMTLKPEEEKQLVKSAETLWGVQKELTL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCA3_TRYCC
Sequence: MGFDFGCLLKLCSTVLKPGGAPGPINYMEIGLNLIKIAAPYIVQYLGIMERPPRVDVEEFFQQAEVTEGFKPWEAPTHVSGTFRALFIGINYYCTSAELSGCCNDVKQIIATLQRKRIPIDEMSILVDERGFPGANGLPTRDNIVRYMAWLFGGAKPGDVLFMHYSGHGTHTRATSDTEEKFDQCLAPVDFSTKGCILDNDIFRILLSGLLQGVRLTVVFDCCHSGSMLDLPYTFVGSRSLRRSVAGHMQRIRKGNDCAGDVLMISGCADEQTSADVSNAATFGTGASGAGGAATQCLAYTILKVSNLSYQDMLIATRDMLRRKGFTQVPQLSASKPINLQQKFSLMTTFEVDPAVAT
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine or lysine residues (PubMed:22402587).  In epimastigotes, may play a role in cell cycle G1/S transition (PubMed:22402587).
What are the official names of this protein?
Metacaspase-3, TcMCA3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to cytoplasm in epimastigotes (PubMed:16213036). Translocates to the nucleus following apoptosis induced by human serum (PubMed:16213036).
Protein: CUC11_CANPG
Sequence: GDIIDVDNDLFEHEQDGVAGTSVHGEYEAYDAYGNEYEVKYIADHLGFRVL
What are the official names of this protein?
Cuticle protein CP575, CPCP575.
Protein: ACKR1_MOUSE
Sequence: MGNCLYPVETLSLDKNGTQFTFDSWNYSFEDNYSYELSSDYSLTPAAPCYSCNLLDRSSLPFFMLTSVLGMLASGSILFAILRPFFHWQICPSWPILAELAVGSALFSIAVPILAPGLHSAHSTALCNLGYWVWYTSAFAQALLIGCYACLNPRLNIGQLRGFTLGLSVGLWGAAALSGLPVALASDVYNGFCTFPSSRDMEALKYTHYAICFTIFTVLPLTLLAAKGLKIALSKGPGPWVSVLWIWFIFWWPHGMVLIFDALVRSKTVLLYTCQSQKILDAMLNVTEALSMLHCVATPLLLALFCHQTTRRSLSSLSLPTRQASQMDALAGKS
What is the function of this protein?
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis.  Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor.  Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines.  Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC.  May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels (By similarity).
What are the official names of this protein?
Atypical chemokine receptor 1, Duffy antigen/chemokine receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
What are the subcellular locations of this protein?
Early endosome. Recycling endosome. Membrane; Multi-pass membrane protein. Note=Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane (By similarity).
Protein: CAH_PSESP
Sequence: MQAQVFRVPMSNPADVSGVAKLIDEGVIRAEEVVCVLGKTEGNGCVNDFTRGYTTLAFKVYFSEKLGVSRQEVGERIAFIMSGGTEGVMAPHCTIFTVQKTDNKQKTAAEGKRLAVQQIFTREFLPEEIGRMPQVTETADAVRRAMREAGIADASDVHFVQVKCPLLTAGRMHDAVERGHTVATEDTYESMGYSRGASALGIALALGEVEKANLSDEVITADYSLYSSVASTSAGIELMNNEIIVMGNSRAWGGDLVIGHAEMKDAIDGAAVRQALRDVGCCENDLPTVDELGRVVNVFAKAEASPDGEVRNRRHTMLDDSDINSTRHARAVVNAVIASIVGDPMVYVSGGSEHQGPAGGGPVAVIARTA
What is the function of this protein?
Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine.  Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.
What are the official names of this protein?
Cyanuric acid amidohydrolase, CAH.
What is the protein family that this protein belongs to?
Belongs to the cyclic amide hydrolase (CyAH) family.
Protein: H3_CRYNB
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKQAPSQVSGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQEASEAYLVSLFEDTNLAAIHAKRVTIQPKDLQLARRLRGERS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HTPG_BURM7
Sequence: MTQQTMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEALENNALYESDPNLRIRLSFDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFSKLSGDQQKDAALIGQFGVGFYSGFIVADRITVETRRAGLPASEGVRWESAGEGDFQVDTIERAARGTTITLHLREGEDELLSSYRLKSIVQKYSDHVALPILMKKEEWDQEKGEMVEKDEDETINQASALWTRAKSEVTDEQYKQFYQHVAHDHQDPLAWTHNRVEGRSEYTQLLFVPSHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQYLRFIKGVVDSSDLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWSAFGQVLKEGVGEDHANRERVAKLLRFASTHGDTDAQDVALADYVARMKPEQTKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLHEFDGKPLASVARGDLDLGALNDDEKKAQEETGEAMKPVVDKMKETLGEKVKDVRVTFRLTDSPSCLVADDNDMSGYLQRMLKAAGQSAPSFQPILEINPEHPLVKALKADGADFGDWCHLLFDQALLAEGGALEDPASFVKRTNALLLSRAA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_STRT1
Sequence: MKVIDGTIASPLGFSADGLHAGFKKRKMDFGWIVSEKPASVAGVYTTNKVIAAPLIVTKTSVKKAGKMRAIVVNSGVANSCTGTQGLEDAYTMQEWTAEKLGVEPDMIGVASTGIIGELLPMDTLKNGLSKLVVNGNANDFAKAILTTDTATKTIAVTETFGRDVVTMAGVAKGSGMIHPNMATMLGFITCDANISSDTLQLALSQNVEKTFNQITVDGDTSTNDMVLVMSNGCALNDEILPDTPEFDKFSKMLNFVMQELAKKIAKDGEGANKLIQVDVVNAPNALDARMMAKSVVGSSLVKTAIFGEDPNWGRILAAVGYAGVDVPVDNVDIMLGGLPVMLASSPVTFDDEEMKDIMHGDEVTITVDLHSGQEKGTAWGCDLSYDYVKINALYHT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSO1_YEAST
Sequence: MHNTGKRYSETAKKVAAGRARKRRQAYEKDQLEKQQLEAQEAQRWEEGARTPNQKKLIMEQKKTEKLRAKKERDQLLAAEEEALGKGGRGKRY
What is the function of this protein?
Likely to play a role in iron homeostasis.
What are the official names of this protein?
Protein LSO1, Late-annotated small open reading frame 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Under iron-replete conditions, enriched in the nucleus. Under iron-depleted conditions, expressed in both nucleus and cytoplasm.
Protein: NOP9_ASPFU
Sequence: MPREKQKRGRRAEDKAKKDAAKRKRDEGPEESAVKRLKPSAETNTSNNEIISGADYIPLGQDDGGNDVPMNDAPANDMPFYGLLDSEEQEYFSKANEVLELNQFHDAEERRLFVDSVYREADGKELKVACSQSCSRLMEKLISLSDMRQIRRLFSKFIGHFLHLVQHRFASHCCETLFINAAPGVTEKISKSKGRKAEVDEEDEPEPELSLAEMFMKVVEELEGNWGYLLTERFASHTIRVLLFVLAGEPVDLSSTDSVVASRKKERLGIVNTEAPEEKAAAEKRKVPEVFEATLKKVMNDMVSGLDNTYLRALATHPVGNPVLQVLVFLELSHFGKASAKDPNSIIRRLIPDDDFGENAESSTFVRGLLYDPVGSRLLETIIKSMPGKLFKSLYKNIIRDRIGSLARNTTAGYVVLRTLERLGKDDLQDAMESIIPEIPGLIERSRLIVPKVLIERCLVRGVDTKPLSDALESAYDKDPAQRLEQMLKLEPAASEDDSEEKRKQTGNNQTAAAEKLHGSLLAQTMLTASGPVSGLIYSSLLAQSPDSLLRLAKDPTASRVLQQALTAPTSTSQFRRQFTTRFSGHLVELALDSSGSHVVDALWPATKDLFFVKERMAQELLNEELSLRDSFVGRAVWRNWSMDLYKRRRGEWASKAKGLDSIENGQRERPKSRIDLARAKFAAKAAEESSKAPVAAKT
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein nop9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.