PharMolix/UniProtQA huggingface dataset:
Protein: RSMH_RALSO
Sequence: MTTQASTGLRHQTVLRDEAIDALLWRDDGIYIDGTFGRGGHSRLILERLGPGGRLIAFDKDPAAITEAGTVEDARFAIEHDSFAHLDAALDARGIGRVAGVLLDLGISSPQIDEGARGFSFRMDGPLDMRMDTTRGITAAQWLAEADERDIARVIRDYGEERFAVQIAKAIVARRRESGTRGPLDRTSELAALVAQAVKTREKGQDPATRTFQALRIHVNQELADLETGLKSAFERLEQGGRLVVISFHSLEDRIVKRFMQALARPEQSAAPEMRRAPLRAHELPAPQLRLLGRVRPSEAEVSANPRSRSAIMRVAERC
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXYD6_HUMAN
Sequence: MELVLVFLCSLLAPMVLASAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN
What are the official names of this protein?
FXYD domain-containing ion transport regulator 6, Phosphohippolin.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HYPA_METM7
Sequence: MHELSYATSVLNAILEAVEQQEALGRKVIKVNDINLEIGELTLLSVDQLQFVFEVISEDTVCKGAELKAEMVKPKIFCMDCEFEGDLDTKDELEVICPKCESRNVKLKGGKEFNIVNATIEFDDEE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: CCL7_HUMAN
Sequence: MKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL
What is the function of this protein?
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils.  Augments monocyte anti-tumor activity.  Also induces the release of gelatinase B.  This protein can bind heparin.  Binds to CCR1, CCR2 and CCR3.
What are the official names of this protein?
C-C motif chemokine 7, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, MCP-3, NC28, Small-inducible cytokine A7.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4443_BACCZ
Sequence: MKMTSKKMKDELMKKLSRPEWDFHYDSEKEVLRIEQKDSKKGINVSLPGVVAKWEVNKEKAIEEVAYYVQEALIAMHKEENSAAKILPVIRSTSFPKQAEEGNPFIMTDHTAETRIYYALDSNKTYRLIDERLLQKLGLTEQQVREMALFNARSLSYEFKQDTVAGNTFYFLNTNDGYDATRILNESLLQSMREKISGDMVVAVPHQDVLIIADIVNEIGYDIIAQMTMKFFAEGHVPITSLSFVYEDGDFEPIFILAKNRKKTDGKEKG
What are the official names of this protein?
UPF0354 protein BCE33L4443.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: PEPS_ARTBC
Sequence: MRGLSYFVLALSAIDAAAAASLPFLRSLQHVGRRDPAARNLPNYDFSAIPPVEKRQTASRLNGKTKKYAVDGTKIPEVQFDIGESYAGLMPISTRKDESRELYFWYFPSENPAAKDEITIWLNGGPGCSSLEGLLQENGPFLWQYGTLYPVPNPWSWTKLTNMVWVEQYNPTDDNPSRPVGTGFSQGKPSVRSQEDVATQFLGFFRNFVDTFDLHGKKIYIVGESYAGLYVPYIAHAMFEKKNKRYFNVESTMIFDPSINKDEILTQVPAVPFVEHWKGLFPFNETFTKQIHDMADKCGYSSYMKEHLVYPPKGKLPALPKATPECDVWTAIFDAVSLVNPCFDVYQVATTCPLLYDVLGYPGSFEYLPAGANVYFNRTDVQKAINAPLQKWTECSERPVFVDGKDNSEPSSFTIIPDVIEKSPRTIIAHGDLDYVLISNGTLLSIQNMTWGGAQGFSQEPSKPLFVPYHDRGSLSTLSGAGVLGRHHTERKLTYVELYLTGHMGPQYNPSASYRILEYLLGRIDDLSK
What is the function of this protein?
Removes acidic, neutral and basic amino acids as well as proline from the C-terminal position.
What are the official names of this protein?
Probable serine carboxypeptidase ARB_06414.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYT_CUPTR
Sequence: MIAITLPDGSRREFPGPVTVAEVAQSIGAGLAKAALAGKVDGQLVDTSYKIERDAELAIVTDKDADGVDVIRHSTAHLLAYAVKELYPDAQVTIGPVIENGFYYDFAYKRPFTPEDLAAIEKKMTELARKDEKVTREVWNRDEAVALFESMGEKYKAEIIGSIPADQEIGLYREGNFVDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDANNEMLQRIYGTAWAKKEDQEAYLHMLEEAEKRDHRKLGKTLDLFHLQEEAPGMVFWHPKGWQVWQAVEQYMRGRLTDAGYDEVRTPQVMDRSLWEKSGHWQNYKENMFVTESEKRDYAIKPMNCPGHVQIFNHGLRSYRDLPLRLAEFGACHRNEPSGALHGLMRVRGFVQDDAHIFCTEEQIVAEAKAFNELAFSVYDDFGFKDVKVKLSLRPDQRAGSDEIWDHAEEGLRLALRACGVEWEELPGEGAFYGPKVEYHIKDAIGRSWQCGTLQLDLVLPERLGAEYVSEDNSRKRPVMLHRAILGSFERFLGILLENHAGALPAWLAPDQVVVMNIADSQAEYAESVVQLLQKQGFRAKADLRNEKITYKIREHSLQKVPYLLVVGDKERDANQVAVRARGNVDLGVMPVSAFVERLQHDVASKA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_VIBVY
Sequence: MKAYQREFIEFALEKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLARLGRFYAAALADSGIEFDVLFGPAYKGIPIATTTAVALADHHDIDTPYCFNRKEAKDHGEGGNLVGSALEGRIMLVDDVITAGTAIRESMEIIQANGADLAGVLVAIDRQEKGKGELSAIQEVERDFACAVISIVSLSDLITFLEEKGDTAEHLDAVKAYRAQYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CCA_ACIB5
Sequence: MQVYLVGGAVRDYLLGHPYQEKDYVVVGATPEHMLAQGFQPVGKDFPVFLHPETKEEYALARTERKSGQGYHGFQFFTDTTVSLEDDLIRRDLTINAIAMDQDGKIYDPYGGQNDLENKILRHVSEAFAEDPLRVLRVARFAARYFPYGFQIAPETLQLMQTMADSGELDALTPERVWKETSRALMENHADIYFQTLRDCGALKHLFPEIDALFGVPQRPEYHPEVDCGIHTLMSLQQACKSNYSLDVRFAVLVHDLGKALTPAEELPRHIMHEERGIKPVTQLCERLRVPTQTKQLALSVCKEHLKCHQIMSLKPGTLWRLLQRLDVLRRPERVEAFVQACECDAKGRLGLEDRPYPQAQYMREAMQIVRSIKVQDLPENIKGAEIGEMLIQYRIEALAEFKNQHQSLSHS
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: IF2G_CRYNH
Sequence: MSAINDPIAAASSGPSEPVQEVQVDVTKLTALSPEVISKQATINIGTIGHVAHGKSSTVRAISGVQTVRFKNELERNITIKLGYANAKIYKCQNPDCPPPSCFKSYPSSKEAHPKCERPGCDGRMDLQRHVSFVDCPGHDILMATMLTGAAVMNGALLLIAGNESCPQPQTGEHLAALEIIGVDPKNIVILQNKMDLVRESEAMEHCESIKKFVEGTTARLAPIIPVSAQLKFNIDAVVAAICNIAPPNYDFSADPRMVVIRSFDVNKPGAGVDELKGGVAGGSILQGVFKVGQEVEIRPGLITRDANGVCTCRPLRSRIVSLHAEQNHLQFAVPGGLIGVGTLVDPALCRADRLLGMVMSSVGKGPSIYVEIRAEVFLLRRLLGVKTDDSKKAKVGKLVVGETLFVNIGASQTGGRITAVKGGDVSIALTTPACCEKGEKIALSRRIDKHWRLIGWGKVRSGGTLCEVVDPE
What is the function of this protein?
As a subunit of eukaryotic initiation factor 2 (eIF-2), involved in the early steps of protein synthesis.  In the presence of GTP, eIF-2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex and initiation factors eIF-1, eIF-1A and eIF-3 to form the 43S pre-initiation complex (43S PIC), a step that determines the rate of protein translation.  The 43S PIC binds to mRNA and scans downstream to the initiation codon, where it forms a 48S initiation complex by codon-anticodon base pairing.  This leads to the displacement of eIF-1 to allow GTPase-activating protein (GAP) eIF-5-mediated hydrolysis of eIF2-bound GTP.  Hydrolysis of GTP and release of Pi, which makes GTP hydrolysis irreversible, causes the release of the eIF-2-GDP binary complex from the 40S subunit, an event that is essential for the subsequent joining of the 60S ribosomal subunit to form an elongation-competent 80S ribosome.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must be exchanged with GTP by way of a reaction catalyzed by GDP-GTP exchange factor (GEF) eIF-2B.
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: O3628_CONAE
Sequence: RRSLTRRVPEECEESCEEEEKTCCGLENGQPFCSRICWG
What are the official names of this protein?
Conotoxin ArMSGL-013.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O3 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DML1_ASPNC
Sequence: MHEIITLQLGQRANYLATHFWNLQESYFTYNEEEESPVDHDVHFRPGVGADGSETYTPRTVIYDLKGGFGTLRKYNALYELTEDATPGQGLWDGREVLQQQAPIPQSDYQKSLDAGLPAPTLSAETVRYWSDYNRLFYHPRSIVQLNDYELNSKIMPFEDWTIGEELFNELDKEHDLLDRDVRPFAEECDQLRALQVFTGSDDAWGGFAAKYIDRIRDEYGKKSVWVWAIENGKKVDRQTQFKRDLNKARSVHAISTQASLYAPIIDPPSRIPQSIYLDARSEWYTSALVSAAMESVSLPTRLRPYHDFEASLAGDDGTHKIFELQSTMVQDGEDAANSPIKTEFDLDFTYDGLACKNSHHVFNQLQVSRGLADGGGESGGEDQGILRRKRHFNSEPMFQRFHTTLPFPILDSFPQNMFPELKSKEKINILAALTVSSRTAERLKVYETLAGRVAGVDERETLVNGLGEIRETYETGWMSDSDFDDD
What is the function of this protein?
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
What are the official names of this protein?
Protein dml1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FPG_ECOSE
Sequence: MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: EP153_ASFK5
Sequence: MFLNKKYPSLIEKKMDDLMTLKFCYLIITFLIITNIFSLAINIWGGGDMIDRQSCENIFYCPKDWVGYNNACYYFSNNNKNYTDANNYCKNSHNSTLANNDTKLLNLTKLLNLSKLYYNDSTYWVKYSLPKNKAVTLRNSTYKYDRVKYTETFFICSN
What is the function of this protein?
Down-regulates MHC-I expression by impairing the appropriate configuration or presentation into the plasma membrane of the latter (By similarity).  Participates in viral hemadsorption, which may help viral spread (By similarity).  Reduces the transactivating activity of host TP53, thus inhibiting apoptosis (By similarity).  Non-essential for virus growth in swine macrophage cell cultures (By similarity).
What are the official names of this protein?
Lectin-like protein EP153R, pEP153R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus lectin-like protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: KBAY_ECO45
Sequence: MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires KbaZ subunit for full activity and stability.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Ketose 1,6-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily.
Protein: VRAA_STAAS
Sequence: MNVILEQLKTHTQNKPNDIALHIDDETITYSQLNARITSAVESLQKYSLNPVVAINMKSPVQSIICYLALHRLHKVPMMMEGKWQSTIHRQLIEKYGIKDVIGDTGLMQNIDSPMFIDSTQLQHYPNLLHIGFTSGTTGLPKAYYRDEDSWLASFEVNEMLMLKNENAIAAPGPLSHSLTLYALLFALSSGRTFIGQTTFHPEKLLNQCHKISSYKVAMFLVPTMIKSLLLVYNNEHTIQSFFSSGDKLHSSIFKKIKNQANDINLIEFFGTSETSFISYNLNQQAPVESVGVLFPNVELKTTNHDHNGIGTICIKSNMMFSGYVSEQCINNDEWFVTNDNGYVKEQYLYLTGRQQDMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNERFGQIGVLLYSGDVTLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKIAREKMMSMYLRGEL
What are the official names of this protein?
Putative long chain fatty acid-CoA ligase VraA, Acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: IF3C_GALSU
Sequence: MLEKSKQKNSFDKNKFIINNKISFPIVRIIDENNYQLGIYKIEDALKLAEEKNLDLVLINDKTEPPVVRIIDYGKFKFAQEKKSREAKKKQHQVTVKEIKMRYKIEDHDYQVRINQAIKFLKLGNKVKISLTFKGREIQYIDLAEKLIEKIIHSLSSLAEHEKVFDKEGKNIYIMLLPKKT
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CDH_ECO24
Sequence: MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQCEILR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRHO_DEIRA
Sequence: MPEPHPAPQPYTVAALYQFRALPDPAALRAELLALGERLELCGTLIVADEGINGTVAGSAAAIAELHAFLLASGFDRLEYKESQASEKPFKRYKVRLKKEIVTLGVPVAPREQVGTYLDPQAWNDLLADPEVIVVDTRNRYEVKAGTFQGAVDPEIDSFREFPAWVDEHLAGAEGKKIAMFCTGGIRCEKSTSLLLQKGFQDVYHLKGGILKYLEDVPQAQSRWDGECFVFDGRVTVGHGLQEGDAVMCHSCGWPLTAQERAHPQFEEGVSCEHCFDETTDVQKAAFRERQRMYEAGHLT
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: T2R41_GORGO
Sequence: MQAALMAFFMLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRXCLQLVGTVHNFYYSARKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHPTFLWLKWRFPGWVPWLLLGSVLISFIITLLFFWVNYPVYQELLIRKFSGNMTYKWNTRIETYYFPSLKLVIWSIPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISFLFLYALSFLSLIIDATKFISMQNDFYWPWQIAVYLCISVHPFILIFSNLKLRSMFWQVLLLARGFWVA
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 41, T2R41.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CYC_BOVIN
Sequence: MGDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFSYTDANKNKGITWGEETLMEYLENPKKYIPGTKMIFAGIKKKGEREDLIAYLKKATNE
What is the function of this protein?
Plays a role in apoptosis.  Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol.  Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity).
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: FPG_SYNWW
Sequence: MPELPEVETIKNNLQEILPLRIKELEIRREDILRCRDYALEELTGQIIEEASRRGKYLILAVDNGLFLVFHLGMSGRLYIQEEETTVLEPHVHVIIHLDKRLKLLYQDARRFGGLWLLKDTQCFFSRLGKEPLSEEFCPRYLEQVLQGRQTAIKNLLLNQNLISGIGNIYADEALFMAGIRPDRQAASLSVREIEGLCCGIKEVLAKSIKYRGTTFRDYRDGKRQPGEFQNHLQVYGRFNQACPNCGQPLKRSRIGGRSSHYCEKCQQ
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RLMH_BURA4
Sequence: MKLFILAVGHKMPGWIASGFDEYTKRMPPELRIELREIKPELRSGGRSAESVMAAERQKIEAALPKGARIVALDERGRDWTTMQLAQALPAWQQDGRDVAFVIGGADGLDPELKARADVLLRISSMTLPHGMVRVLLAEQLYRAWSITQNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNISR_MOUSE
Sequence: MWDQGGQPWQQWPLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSIVEQPPGMMPNGQDMSAMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPEQPWMPPAPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGGPPDNFAVGPVNQFDYQHGAAFGPPQGGFHPPYWQPGPPGPPAPTQNRRERPPSFRDRQRSPIALPVKQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEDEDAENLEAVSSGKVTRSPSPAPQEEHSEPEMTEEEKEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLQDKQIEEEKQQTERVTKEMNEFIHREQNSLSLLEASEADRDAVNDKKRTPNEAPSVLEPKREHKGKEKERGSRSGSSSSGSSSSGSRTSSSSSSVSSSSYSSSSGSSCTSSRSSSPKRRKRPSRSRSPPAKARRSRSRSYSRRVKVDSSRTRGKLRDRRRSNRSSIERERRRNRSPSRDRRRSRSRSRDRRTNRSSRSRSRDRRKIEDPRGNLSGNSHKHKGEAKEQDRKKERSRSVDKDRRKKDKERDRELDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFCRSGSISVKVIRHDSRQDSKKNATKDSKRHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSLEKSQRSGKKASRKHKSKSRSR
What are the official names of this protein?
Arginine/serine-rich protein PNISR, Serine/arginine-rich-splicing regulatory protein 130, SRrp130, Splicing factor, arginine/serine-rich 130, Splicing factor, arginine/serine-rich 18.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: CDO_ARTBE
Sequence: MPFIENQTTTAEPIVPVDVKGKDAFHKLVDDLSAVLGPSSGLDSDDVDPMDIQKLMEGYVSNHEEWQRYALADESRAYTRNLVDEGNGKSNLLVLVWNPGKSSPIHDHANAHCVMKILHGSLKEHRYDWPEQDKINNGEACPLTVTKETILRENEVAYMSDKLGLHKISNPDPNDFAISLHLYTPPNAAHFGCSLFDEKTGKSHHIKQCTFFSNRGLKL
What is the function of this protein?
Cysteine dioxygenase involved in sulfite formation from cysteine.  Required for keratin degradation and plays an important role in filamentous growth and virulence.
What are the official names of this protein?
Cysteine dioxygenase, CDO.
What is the protein family that this protein belongs to?
Belongs to the cysteine dioxygenase family.
Protein: NTCP5_MOUSE
Sequence: MSGNFFIFLLLLVTPGEAKKSFLSFLNIQNTEMLSFTRTEENIVVRSSYKDKQPHSSYLLVKLEDPKVLQVVNVTKTSLAVTDFTVNLKTFPGETNVTLQLWESEGRQTTLIDELKNVRVRVFRQTDDSLLQAPIHVDSSIFLLVLSMILLNKCAFGCKIEFQVLQTVWKRPLPILLGVVIQFFLMPFCGFLLSQILGLPKAQAFGFVMTCTCPGGGGGYLFALLLEGDVTLAILMTCTSTSLALIMMPVNSYFYSRLLGLAGAFHVPVLKIVSTLLFILMPMSTGVIIKHKMPAKAICLERVVRPLSLTLMFVGIYLAFRMGLVFLRMANLEVFLLGLLVPALGLLFGYSLAKVYLLPLPVCKTVALETGMLNSFLALAIIQLSFSQPKAHEASVAPFTVAMCSSCEMLLLLLVYKAKRRPSLSTEYEKTPLV
What are the official names of this protein?
Sodium/bile acid cotransporter 5, Na(+)/bile acid cotransporter 5, Solute carrier family 10 member 5.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OXLA_DEMVE
Sequence: MNVFFMFSLLFLAALESCADDRRNPLGECFREADYEEFVDIATNGLKQTSNPKRVVVVGAGMAGLSAAYVLAGAGHNVMLLEASERVGGRVNTYRNEQEGWYVNLGPMRLPERHRIVREYIKKFGLQLNQFFQEDEDAWYFIKNIRKKVREVKENPSIFPYPVKPSEKGKSAPQLYRDSLQKIIEEYGRSNCSYILNKYDTYSTKDYLIKEGNLSPGAVDMIGDLLNEGSSYYLSFIESLKSDDIFSYENRFDEIVGGFDLLPKAMYKAIEEKVHLNARVIQIQQNAEGVRVTYQTPAKNLSYVTADYVIVCSTSRAARRIYFEPPLPPEKAHALQSIHYRSATKIFLTCTKKFWEDDGIHGGKSITDRPSRLIHYPNHNFPNGIGVLVIYTIADDADFFLALDNKTIADIVIHDLSLIHQLPKEKIRDLCYVSMIKKWSLDKYSMGSITTFAPYQFQEYFETVAAPVGRIYFAGEYTARAHGWIDSTIKSGLKAARDVNRASQKPSRIQLSNDNEL
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme.  Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation.  Its effect on platelets is controversial, since it either induces aggregation or inhibits agonist-induced aggregation.  These different effects are probably due to different experimental conditions.
What are the official names of this protein?
L-amino-acid oxidase, DvLAAO, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2028_KORVE
Sequence: MADNSFDIVSKIDLQEVSNAIQQATKEIQTRFDLKDTKSEIKLEKDAIELHSSDEYKLKAVTDILQGKLVKRNVPLKGLTYGTIESAAGATVRQKITMQQGIPGEKAKEIVRVIKDSKKKAQASIQGDTVRVSSKDRDTLQEIIALIKNKDFGIDVQFTNYRSN
What are the official names of this protein?
UPF0234 protein Acid345_2028.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.