PharMolix/UniProtQA huggingface dataset:
Protein: LFTR_PELPB
Sequence: MIRIDELLRAYRRGYFPMSDPEDEKVYWCQPYKRAVFCLDSYRPSRDVLRLTRKKEFTVTLDKEFAGVIKGCAAPRKNDHETWISDEIIEAYTKLHSLGIAHSFESWYQGELVGGLYGIALGGAFFGESMFSRRSYASRIAFDHLVFHLREKGYLLLDAQIMNPHLQRLGAVEIEHEEYMRQLAHALQKKIVFL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNK7_ARATH
Sequence: MEGSEDASAIVEPPDPEVLEIDPTCRYIRYKEVIGKGASKTVFKGFDEVDGIEVAWNQVRIDDLLQSPDCLERLYSEVRLLKSLKHKNIIRFYNSWIDDKNKTVNIITELFTSGSLRQYRKKHRKVNMKAVKCWARQILTGLKYLHSQDPPIIHRDIKCDNIFINGNHGEVKIGDLGLATVMEQANAKSVIGTPEFMAPELYDENYNELADIYSFGMCMLEMVTFEYPYCECRNSAQIYKKVSSGIKPASLSKVKDPEVMKFIEKCLLPASERLSAEELLLDSFLNVNGLVMNNPLPLPDIVMPKEGSFGERCLMSEGPPNARNRTMSMNLDEDNNLPIVISSNNSGTNCIEVRRAKRGNFFVLKGEENDENSVSLILRIVDENGRVRNIHFLFFQEGDTASNVSSEMVEQLELTDKNVKFIAELIDVLLVNLIPNWKTDVAVDHLIHPQQNQSSKDNHQNGASSQAGESISHSLSSDYCPRSDDEANPTVAATTEDQEAEKPGSLEEEEEDERLKEELEKIEERFREEMKEITRKREEATMETKNRFFEKKMQQVE
What is the function of this protein?
May regulate flowering time by modulating the photoperiod pathway.
What are the official names of this protein?
Probable serine/threonine-protein kinase WNK7, AtWNK7, Protein kinase with no lysine 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily.
Protein: RS16_MYCBO
Sequence: MAVKIKLTRLGKIRNPQYRVAVADARTRRDGRAIEVIGRYHPKEEPSLIEINSERAQYWLSVGAQPTEPVLKLLKITGDWQKFKGLPGAQGRLKVAAPKPSKLEVFNAALAAADGGPTTEATKPKKKSPAKKAAKAAEPAPQPEQPDTPALGGEQAELTAES
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PGMR_ASPTN
Sequence: MADSTPVRMPRAPKLRASCDECGAAKLKCDRGHPSCGRCISLGLKCVYGVSRKAGKPRRDAQSATRPPPTPGDSGPPLDYNSFGPTSPPSSVGDGATLASGLLPGAADLSPLDWGPGSSSSYRAVVDLCSRYAKEPMRMDDTAMSSVWDGFLEPSLFATYGSPVQVARLAGGSVPFSAAPVRDLPI
What is the function of this protein?
Transcription factor that specifically regulates the expression of the pgm gene cluster that mediates the biosynthesis of cryptic naphthoquinones derived pigments responsible for the coloration of the fruiting bodies.
What are the official names of this protein?
Transcription factor pgmR, Pigmented naphthoquinones biosynthesis cluster protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: IFNT2_BOVIN
Sequence: CYLSEDHMLGARENLRLLARMNRLSPHPCLQDRKDFGLPQEMVEGNQLQKDQAISVLHEMLQQCFNLFYTEHSSAAWNTTLLEQLCTGLQQQLEDLDACLGQVMEEKDSDMGRMGPILTVKKYFQGIHVYLKEKEYSDCAWEIIRMEMMRALSSSTTLQKRLRKMGGDLNSL
What is the function of this protein?
Paracrine hormone primarily responsible for maternal recognition of pregnancy.  Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium.  This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity.  This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus.  In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties.  In contrast with other IFNs, IFN-tau is not virally inducible.
What are the official names of this protein?
Interferon tau-2, IFN-tau-2, Antiluteolysin, Trophoblast antiluteolytic protein, Trophoblast protein 1, TP-1, Trophoblastin.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the uterine lumen.
Protein: PPTA_ECODH
Sequence: MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIALQQIQPESWQAIWDAEIAPQMEALIKKPGYSMNA
What are the official names of this protein?
Tautomerase PptA.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family. PptA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT16_MOUSE
Sequence: MDSGKSRSLETTVKRVYRDLLLPKINTSKKMSTLTNSPSSLEGTPGIKKNSGEMQAEASAERVKLTKSIKEKQNNELEKVALKRKADSEEKLVGKKEAKIMELDNQLVTTVPLPHIPLKNIMDVEMKLVYVDEEDVSYEFAQPNMCLGLQATGQTATTMPPASPRDLTTLPQIDKWLQVALKDASSCYRQKKYAVAAGQFRTALELCSKGAALGKPFEAHAEDIASIASFIETKLVTCYLRMRKPDLALNHAHRSIVLNPAYFRNHLRQAAVFRCLERYSEAARSAMIADYMFWLCGGSEHSVSKLIKLYWQAMIEEAITRAEAFSVMYTPFATRIKPENIEKVKEVFMRTHPTYVDCIYTDTQGLHVLPQTADWSCFPPQQYLLTLGFKNKEDGKFLEKVSSRKLPTYTEHKTPFSPLTREDTVRHMETVGKRILPILDFIRSTQLNGNFHACSGVMEKLHYASLLSRLQRVKEQAQVINQAMAELATVPYLQDISQQEAELLQSLMADAMDTLEGKKSDKERVWNTIQKVGRIEDFLYQLEDSFLKTKKLRTARRQKTKMKRLQTVQQN
What is the function of this protein?
Essential for spermiogenesis and male fertility (PubMed:29065458).  Involved in the formation of acrosome during spermatogenesis (PubMed:16372119).
What are the official names of this protein?
Spermatogenesis-associated protein 16.
What is the protein family that this protein belongs to?
Belongs to the SPATA16 family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Shift from Golgi to sperm acrosome.
Protein: GCSP_BURO1
Sequence: MKLEHPDRLMNRTPLSLAALETHDAFAERHIGPDAASQQAMLDTLGFASRAALIDAVIPASIRRAETLPLGPFAQPKSEAEALAALRALADKNQVFRSYIGQGYHDTHTPAVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQQMVADLTGLAISNASLLDEATAAAEAMTLLQRTGKPKSNVFYVADDVLPQTLEVIRTRALPIGIEVKTGPAADAAQANAFGVLLQYPGVNGDVRDYRALTDAIHAAGGHVVVAADLLALTVLTPPGEWGADVAIGNTQRFGVPMGFGGPHAAYLAVRDEFKRQMPGRLVGVTVDAQGKPALRLALQTREQHIRREKATSNVCTAQALLAIMASMYAVYHGPHGLKTIALRVNRIAALLAAGVKQLGFATVNDTFFDTLTIDTGARTAQVHEFAKAKRINLRRVSDTQVGVSVDETTTRDDLADLLDVFAQAAGGTAPAVDALDAGLAGVAALPAGLERTSAYLTHHVFNRHHSETEMLRYLRSLSDKDLALDRSMIPLGSCTMKLNATSEMLPVTWPEFGGIHPFAPAEQTVGYREMIDQLEEMLVAATGYAAVSLQPNAGSQGEYAGLLIIHAYHASRGEGHRDVCLIPASAHGTNPASAHMAGMKVVVVACDAQGNVDIADLKAKAEQHSANLAAIMITYPSTHGVFEQNVREICEIVHAHGGQVYVDGANMNAMVGLTAPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGAHLAKFLPNQRSTGYARAEDGIGAVSAAPYGSASILPISWMYIAMMGAKNLTAATETAILNANYIAKRLAPHYPVLYSGPGGLVAHECILDLRPIKETSGISVDDVAKRLMDYGFHAPTMSFPVPGTLMVEPTESESQEELDRFIAAMIAIREEIRAVEEGRADREDNPLRHAPHTAAVVTANEWPHAYSREQAAYPVASLGTNKYWPPVGRADNAYGDRNLFCSCVPMSDYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: MEDB_GIAIN
Sequence: MSEAMVFSKIDEYTLFMSRSLQKSLKTFAEQVMALIYQYKDTLVEDRLALTNTLDEAVQILVDSGKEEADKLGFNIYSAVSRYISEIWASQSGQTTAAPPATDIDGLHRQLVALKNSLGQNAELYEQRCQLQAELRELQEFSENPAAAVEEIMQLKAQIDELKYGASNHNALVQEKRDLERHLADLRLSRQDTNSRLPQEIDRLRAEIEDEKRNLPHMDDLQRQRDELQRQLDTIRRRGNTSGVMAEIENIQRQIDDANSSASSEHELRMLRAEVETLRAQKSIVTRLEAENADLRRELQDIRGRAQEMSASQRYSANQAQELQEKAMQAEELLQQKIELRRQLHEALERADAGEAALRDKRRLEDEIKGLQLRLTENDFTKERSILRNEIQAKTTEIDTLISDRRALETKLLNKEAEVDQLLYEKQLLKTELNSYRGTNEDIDKLTFEKRQLVEELNDLREKTIKYDQLAREKAALETELKENSYNFDQLLEQKQQMRSDLNALREKAADYERVDRELRLKDKELEEKNAEIERLLEDRRVMRTELLHSKESATDVDSLIQEKRLRDRELAHLRDRMSEYERVVEERIQKEKENNLLKQRITELEQQQRTATVRETEMSALREKANELDGYNRERQAREHEINMLRDKALESDKLRQDNRVMAMELTELREKVQLLEKLQYEKRARDVEMLELRHKAMDVDTLVEEKQRLEMRLAELKIKVNNYDQLADDKARLQEQLKEMSDKLIEFEMIMDDNRRLKLQVKELDLKTANMEKLYEEYKKLEDQLKATKAMTSTGMGVSAASPAFYKTKSMRLTQQNNQMKNTTDNLLTRDIPKLIDKLIERPAGTTTMGRSGKF
What is the function of this protein?
May have a role in immobilizing the microtubules between cell divisions.
What are the official names of this protein?
Median body protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Median body.
Protein: Y415_GEOSW
Sequence: MDLSKKSAENVAYMVEKIKEKLKVLNFDAIKPSHFSEEWYDELKDIYEMVMRKNTFSPSEMQAIAEELGNLRKK
What are the official names of this protein?
UPF0435 protein GWCH70_0415.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: MURD_STAAS
Sequence: MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVVSGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTNGKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKPHIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLYFSTQQEVDGIYIKDGFIIYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIIDSLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFDELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSPACASWDQYSTFEERGEKFIERFRAHLPSY
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_YERP3
Sequence: MQTSPLLESLMEALRCLPGVGPKSAQRMAFQLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEHCTICLNPRRQQNGQICVVESPADIHAIEQTGQFGGRYFVLMGHLSPMDGIGPGDIGLDLLEKRLSTEAISEVILATNPTVEGDATANYIGQMCGQYGILASRIAHGVPVGGELEMVDGTTLSHSLAGRNPIKY
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: UVRC_FINM2
Sequence: MFDIKKELQKVPHKPGVYIMHDKNDEIIYVGKAIDLRRRVGQYFDSSKKLAKVAAMVSHVEYFEYIIVNNECEALVLESNLIKKNSPKYNIVLRDDKQYPYIKITNEKFPRVLKTRRVLKDKAKYFGPFPNAYAVNDIIDLIHETYKIRTCNLNFDKGQKLKRPCLNYYINRCDGMCVYDVNEEDYNKELLEVENFLNGREDELTKKLTDKMMAASKNLNFELAAKLRDSITNIQVILEKQNITNTKGLDLDMISMAREAETVCVQVFFMRNGKIIERQHFIIDNKYEESNEHIVGEFFKQFYIDLTYVPKQILTDIEIEDRDLIEEMLTEKKGSKVEIKIPKRGNKTDLLEMVRVNAKEGLDKYISRHLKRERNRENAILDLQDITGVKPIDRIECYDISNTSGVDSVGSMIVFKNGAKSSKDYRKFKIKTVEGADDYASHREVLTRRFRRLLDSDKKDNSFDEMPSIILMDGGKGQVNIAKEVLNEFNLDIPILGLVKDDKHRTRGIIYENEEIRLKVNTPLYRLLFAIQEETHRFAINYHRKLHEKNFKKSELDNIALIGEKRKKALMKHFKTLDRIKKASVEELCEVDGMNEKAAENIVNYFKQ
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POG_ABPVR
Sequence: PIKKQILPTYIIRNSRRPLKKTQLKRNKSPPFMMWKLQIGSIPPWLKTLHRLGAWMIRTVLFSFYNAPYSLTTLRSLLDQQQMITNPSIDMC
What are the official names of this protein?
Putative protein pog, ORFx protein.
Protein: LIVB7_BRUSU
Sequence: MEKHLIALSVAALLAGAAPASADIKMGSLYPFSGPLALLGDESARGLEIAVEEINAKGGVQGEKIVLVRGDAVDNNQAIGEARRLISVENVAGIFGTFSSGRAVAASQVSELAGVPYFELGAVADEITDRGLENVYRANPYARDFAQMIVEMLQKKIAPKLGKDSKDLKIAVIYEDSSYGTSVAKHEETFLKEAGLNMVLSQSYPGNTVDMSSLVLDLKSAGADVVLQTSYQSDSVLFLQQANEGGYKPSAIVGAGGGYSLQPTADAVGHDVIEAAYDVDFTQFAVNTSFTPGLEEFVEAYKKKYGETPRSGHSLTNYVGAKVILEALNKVKGFDAAAVKQALSAVDIEAGKTAMGYGFKFDQNNQNERASMMGMQWQDGKLVTVYPDAAAISEIRLPQ
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 7.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: AT2C1_PONAB
Sequence: MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVQQEKARMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAIAIASRLGLYSKTSQSVSGEEIDAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVERSREKIQKHVSSTSSSFLEV
What is the function of this protein?
ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway (By similarity).  Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side.  The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state (By similarity).  Plays a primary role in the maintenance of Ca(2+) homeostasis in the trans-Golgi compartment with a functional impact on Golgi and post-Golgi protein sorting as well as a structural impact on cisternae morphology.  Responsible for loading the Golgi stores with Ca(2+) ions in keratinocytes, contributing to keratinocyte differentiation and epidermis integrity (By similarity).  Participates in Ca(2+) and Mn(2+) ions uptake into the Golgi store of hippocampal neurons and regulates protein trafficking required for neural polarity (By similarity).  May also play a role in the maintenance of Ca(2+) and Mn(2+) homeostasis and signaling in the cytosol while preventing cytotoxicity (By similarity).
What are the official names of this protein?
Calcium-transporting ATPase type 2C member 1, ATPase 2C1, ATP-dependent Ca(2+) pump PMR1, Ca(2+)/Mn(2+)-ATPase 2C1, Secretory pathway Ca(2+)-transporting ATPase type 1, SPCA1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Note=During neuron differentiation, shifts from juxtanuclear Golgi position to multiple Golgi structures distributed over the neural soma with a predominance in the apical dendritic trunk.
Protein: ESL2_MYCPN
Sequence: MASSKSDPFQSIFAFKPHRKRHNFIFLHGFGSEYSSFKHVFKLFEKKRWSFFAFNFPGHGNNQSNSVDELKLKHYVELVCDFIIQKRLKKVVLVGHSMGGAIAVLVNAVLRERIKALVLVAPMNQTSFVVSKKRILDTLFTRSPKNQQDFIEHTDDKKSIVNFFVGAFKKRVNFKTLYSDMVQNAKYGNDYLEAGYNAIKDKPTLVVLGSNDIVTPTKASVEYLAKHSETIIFKIIDGVGHSPHYYAPKLFFDYIGEFLDNIKRNKDK
What are the official names of this protein?
Putative esterase/lipase 2.
What is the protein family that this protein belongs to?
Belongs to the lipase/esterase LIP3/BchO family.
Protein: RECX_LEGPN
Sequence: MTKAFDSALRLLTRREYSAMELCDKLKQKGFSTNDVQNALYECQRLGYQSDVRFVENYIRVRIHQGYGPLKIRQELKNKGIDPDLIQSVLHQEKDNWVNYALRAWEKKFKRQDDFSYSEIQKQQRFLLYRGFDRDVISKVFKEVKSSYLI
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMCA1_LISMO
Sequence: MEIYRKSAAETFTQLEATEKGLTTSEVTKRQEKYGFNELKNKKKDPLWKLFLETFKDPMVIVLVIAALVQLVLGEVVESLIIFLVLIVNSIISVVQTRKAESSLDALREMSAPVAKVIRDGSKQSIHARELVPGDVVILDAGDFVPADGRLFESGSLKIDEGMLTGESEAVEKYIDTIPDEVGLGDRVNMVFSGSLVVYGRGMFVVTGTASETEIGKIAGLLETAEAKQTPLQRKLESFSKKLGLGILALCVLIFAVEAGRVLLGDNSADMATAILNAFMFAVAVAVAAIPEALSSIVTIVLAVGTNKMAKQHAIIRKLPAVETLGSTSVICTDKTGTLTQNKMTVVDYYLPDGTKENFPESPENWSEGERRLIHIAVLCNDSNINSEGKELGDPTEVALIAFSNKNNQDYNEIREKFIREGEIPFDSDRKLMSTLHTFNENKAMLTKGGPDVMFARCSYVFLDGEEKPMTEEILAKLKETNEEFSNQALRVLAYGYKRMPADTTELKLEDEQDIVLVGLTAMIDPPREAVYASIEESKKAGIRTVMITGDHKTTAQAIGRDIGLMDADDIALTGQELDAMPEEELDKKLEHIAVYARVSPENKIRIVKAWQKKGKITAMTGDGVNDAPALKQADIGVAMGSGTDVAKDSAAMILTDDNFVSIVDAVGVGRTVFDNIKKSIAYLFAGNLGAIIAILFALVLDWINPFTALQLLFINLVNDSLPAIALGMEKAEPDVMKRKPRDINEGIFAGGTMRAVISRGVLIGIAVIISQYIGMQISPEMSVAMAFTTLILARTLQTFAARSNVQTAFGAGFFSNKYVIGAVLLCFVLYGITVLPGAREIFSIPASFGLHEWSIAAGLALAAVVMMEIIKVVQNKFFK
What is the function of this protein?
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.  The transport is electrogenic with a probable ATP:Ca(2+):H(+) stoichiometry of 1:1:1.  May have an important role in survival of the bacterium when stressed by a combination of a high calcium concentration and alkaline pH.
What are the official names of this protein?
Calcium-transporting ATPase lmo0841, LMCA1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FTSQ_RHORT
Sequence: MRRVSQPPPRPRHRRRRRRDVLPSLPRASMVFLIAGGVGMAYLAARTPALAGLIGLAPPPALGAPGSSVPPAGARDAGEGWGLGETARVLTRQGLVLRQVTVTGRDLTAGRDILGAIGVPQGGPLLAIDPETVRTRLEALPWVASARVERRLPDQVHVAITEREPMALWQHNGAFAVIDREGRAIAADPGRWRTLPLVVGAGAPGHAAELLNLLTSQPGIAERVKAATLIGERRWTLRLDSIENGLVVRLPEEDPSAALDQLVQIDARDHLLSKNLSVIDMRLPGRLVVRLAEDGPVDPEAEIAGGKPARGAPAGGQKPPPIVRKSEGRDA
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsQ.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. FtsQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: QUEF_CHLTE
Sequence: MNKEIIEVFDNTYPDRDYTIEIINPEFTSVCPKTGLPDFGTITVNYVPDKSCIELKSLKYYFLEFRNAGIFYENITNRILDDLVEACQPRRMTVKTEWNARGGITETVTVSYSKSKE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAU24_YEAST
Sequence: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYSFQVAHPTETYPVEIAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRLKPAISSALSKDGIYTIAN
What is the function of this protein?
Component of the cell wall.
What are the official names of this protein?
Seripauperin-24, Cell wall protein DAN3, Delayed anaerobic protein 3.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PA2A1_PROMU
Sequence: NLWQFENMIMKVAKKSGILSYSAYGCYCGWGGRGTPKDATDRCCFVHDCCYGKVTGCNPKLGKYTYSSENGDIICGGDGPCKEVCECDRAAAICFRDNLDTYDRKTYWKYPASNCQEDSEPC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 1, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YM09A_YEAST
Sequence: MKKKDRDSVFHRNIEIFITILINVVILKSFLLISSWVILVLLLVINDLPMYCYHHSLTYFLGCSKQTYFHRLGYPMQKLRHLLYFYYCYFLPRWKPRRRLTYHRYHPK
What are the official names of this protein?
Putative uncharacterized membrane protein YML009C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PYRG_PROMS
Sequence: MSKFVFVTGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYLNVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTAMTRLNSVTTGSIYQAVINKERRGNYNGGTVQVIPHITGEIRERIHRVAANSNADIIITEIGGTVGDIESLPFLEAIREFKNDVNRNDVAYIHVTLLPYIKTSGEIKTKPTQHSVKELRSIGIQPDLLVCRSDKSINEALKKKLSGFCGVNINSVIEALDADSIYSVPLSLKKEGLCKETLKYLDLEDKKCDLKNWEQLIHNLRNPGDPIKVALVGKYIELGDAYLSVVEALRHACIEQRALLDLHWVSAEMIENNSAETYLNEVDAIVVPGGFGNRGVNGKISAIKFARENKIPFLGLCLGMQCAVIEWARNVANLPDASSSELDPNTPNPVIHLLPEQEDVVDLGGTMRLGVYPCRLTKNTTGKNLYDEDVIYERHRHRYEFNNYYKQSFLDSGYKISGTSPDGRLVELIELENHPYFLACQYHPEFLSRPGKPHPLFKGLIKASQDKLTQSN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: LT_POVBK
Sequence: MDKVLNREESMELMDLLGLERAAWGNLPLMRKAYLRKCKEFHPDKGGDEDKMKRMNTLYKKMEQDVKVAHQPDFGTWSSSEVPTYGTEEWESWWSSFNEKWDEDLFCHEDMFASDEEATADSQHSTPPKKKRKVEDPKDFPSDLHQFLSQAVFSNRTLACFAVYTTKEKAQILYKKLMEKYSVTFISRHMCAGHNIIFFLTPHRHRVSAINNFCQKLCTFSFLICKGVNKEYLLYSALTRDPYHTIEESIQGGLKEHDFSPEEPEETKQVSWKLITEYAVETKCEDVFLLLGMYLEFQYNVEECKKCQKKDQPYHFKYHEKHFANAIIFAESKNQKSICQQAVDTVLAKKRVDTLHMTREEMLTERFNHILDKMDLIFGAHGNAVLEQYMAGVAWLHCLLPKMDSVIFDFLHCIVFNVPKRRYWLFKGPIDSGKTTLAAGLLDLCGGKALNVNLPMERLTFELGVAIDQYMVVFEDVKGTGAESKDLPSGHGINNLDSLRDYLDGSVKVNLEKKHLNKRTQIFPPGLVTMNEYPVPKTLQARFVRQIDFRPKIYLRKSLQNSEFLLEKRILQSGMTLLLLLIWFRPVADFATDIQSRIVEWKERLDSEISMYTFSRMKYNICMGKCILDITREEDSETEDSGHGSSTESQSQCSSQVSDTSAPAEDSQRSDPHSQELHLCKGFQCFKRPKTPPPK
What is the function of this protein?
Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation.  Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA.  Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.  Participates in the modulation of cellular gene expression preceeding viral DNA replication.  This step involves binding to host key cell cycle regulators retinoblastoma protein RB1/pRb and TP53.  Induces the disassembly of host E2F1 transcription factors from RB1, thus promoting transcriptional activation of E2F1-regulated S-phase genes.  Inhibits host TP53 binding to DNA, abrogating the ability of TP53 to stimulate gene expression.  Plays the role of a TFIID-associated factor (TAF) in transcription initiation for all three RNA polymerases, by stabilizing the TBP-TFIIA complex on promoters.  Initiates viral DNA replication and unwinding via interactions with the viral origin of replication.  Binds two adjacent sites in the SV40 origin.  The replication fork movement is facilitated by Large T antigen helicase activity.  Activates the transcription of viral late mRNA, through host TBP and TFIIA stabilization.  Interferes with histone deacetylation mediated by HDAC1, leading to activation of transcription (By similarity).
What are the official names of this protein?
Large T antigen, LT, LT-AG.
What are the subcellular locations of this protein?
Host nucleus.