PharMolix/UniProtQA huggingface dataset:
Protein: IF2_CUPNH
Sequence: MASTTVAQLAAELSRSAAALLEQLQAAGVGKATPEDIITESDKTRLLDYLKRSHGQADDSSRKKITLTKRETSEIRQSDGTGKTRTVQVEVRKKRVLIKRDEAAPDAQADAVEAQAPVVDAVEEARRDEEERQQAELLARQEAEAKAAREAAEREEAERRARQEALEAEQRRQAELAARKAEEEAAASRAVTEANEDSSRKKAEDEKARVTAERAEAQKAADEAKAAADKARAEQEVAARKRREAAEAEARAIQQMLNAPPRVLKAPSERKAEEKKAEQTGTLHKPVKPAGATTEAKKDEKKPATTTTTTATADKKGKVVKAGWQDDSSRKKGSGLKTRGDTSGGVGGWRGGPRGRGGRQQQHDDSRSSFQAPTEPVVREVHVPETVSVADLAHKMAVKASEVIKQMMKLGQMVTINQVLDQETAMIVVEEMGHKAYAAKLDDPEALLVVGGEEHTDAELLPRPPVVTVMGHVDHGKTSLLDYIRRTKVAAGEAGGITQHIGAYHVETDRGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAAGVPIVVAINKIDKPDANPDRVKQELVAEQVVPEEYGGDSPFVPVSAKMGTGVEDLLEQVLLQAEVLELTAPVDAPAKGLVVEAQLDKGKGPIATILVSSGTLKRGDVVLAGSAYGRVRAMLDENGKPTKEAGPSIPVEIQGLSEVPAAGEEVLVLPDERKAREIALFRQGKFRDVKLAKQQAAKLENMLEQMAEGEVQTLPLIVKADVQGSQEALVQSLQKLSTAEVRVQIVHGGVGGISESDVNLATASKAVIIGFNVRADAGARKLAEHNGIDIRYYNIIYDAVDEIKAAMSGMLAPEKRETTIGQVEVRQVFRVPKIGAVAGCMVTDGLVKRNSLVRVLRNNVVIHDGELDSLKRFKDDVKEVKQGFECGLSIKNFNDVQEGDQLEVYEITEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAAI_SALPK
Sequence: MRSVLTISVGLLFGLALSSVAHANDHKILGVIAMPRNETNDLALKIPVCRIVKRIQLTADHGDIELSGASVYFKTARSASQSLNVPSSIKEGQTTGWININSDNDNKRCVSKITFSGHTVNSSDMARLKVIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: HSLV_BURA4
Sequence: MEQFHGTTIVSVRRGDKVALGGDGQVTLGNIVMKGGARKVRRIYNNQVLVGFAGGTADAFSLLDRFEAKLEKHQGNLTRAAVELAKDWRTDRMLRRLEAMLITADATTTLVITGNGDVLDPEGGICAIGSGGAYAQAAARALAENTELSPREIVEKSLEIAGDMCIYTNHNRIIETIE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_VIBCH
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPIKTWSRRSMIIPTMIGLTIAVHNGRQHVPVFVTDEMIGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SYFA_CAMJ8
Sequence: MQNFIEQIQKCENLNDLEAIRISVLGKKGILTEGFTKLKELEDEAKKEFAAKLNAQKEIFNEAYLAKFKDLENLALEERMKQDALNFNYFDESITTGALHPVMSTMDKIIEYFIALNFSIEKGPLIEDDFHNFEALNLPKSHPARDMQDTFYFDDKRLLRTQTSPVQIRTMLAQKPPIRMIAPGAVFRRDFDITHTPMFHQVEGLVVEEGQKVSFANLKSVLEDFLRYMFGDVKVRFRPSFFPFTEPSAEVDISCVFCKGKGCRVCKHTGWLEVLGCGIVDPNVYNFVGYENVSGYAFGLGVERFAMLLHQIPDLRSLFEGDLRLLEQFR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D104A_HUMAN
Sequence: MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP
What is the function of this protein?
Has antimicrobial activity.  Synergistic effects with lysozyme and DEFB103.
What are the official names of this protein?
Beta-defensin 104, Beta-defensin 4, BD-4, DEFB-4, hBD-4, Defensin, beta 104.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: VKT2I_HETCR
Sequence: MKGTFLICLILIAGFYFRSIQGFYFKRIQGNICSEPKKVGRCRGSFPRFYFDSETGKCTPFIYGGCGGNGNNFETLHACRAICRA
What is the function of this protein?
Serine protease inhibitor that also shows protective effect in a cytotoxicity model (PubMed:32144281).  It binds to all proteases tested (trypsin (Ki=52 nM), alpha-chymotrypsin, cathepsin G, kallikrein, and human neutrophil elastase) (PubMed:32144281).  It significantly increases neuroblastoma cell viability in an in vitro neurotoxicity model, being a consequence of an effective decrease of reactive oxygen species (ROS) level in the cells (PubMed:32144281, PubMed:35563513).  It also seems to protect cells by inhibiting ATP-induced purinoceptor (P2RX7) activation (PubMed:35563513).
What are the official names of this protein?
PI-stichotoxin-Hcr2i, PI-SHTX-Hcr2i, Kunitz-peptide HCIQ2c1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: TRPF_CHLFF
Sequence: MKVKICGVTHPEDAEYAALLGADYIGMIFAEKSKRKTSLSMAKSITNTTKRLGAEPVGVFVEQTTDQIIAICEQTGIKTVQLHNSFPSGSLEKLLRDYSIIYAISVRENGDVCHPQSLPPKVIPLYDTEKGGTGKQFNWKAFSSPRDTFWMLAGGLNPANIEEAIATLHPNGVDVATGVEFPNKTRKDPDLLKAFIQSAKILGEKI
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: Y1437_BDEBA
Sequence: MPAAHSESMNKTKIAKIAFPIAALLCFFPFVSSAAALVLGIVLAVALGNPYVDKTRSYTHHLLSLSVIGLGAGMDLMVVGRVGLQGIGYTVVGISFTLLLGMLIGRMLKIERDTSTLITVGTAICGGSAIAAVAPTIRAKSHEVSVALGTVFMLNACALVIFPWIGHLLNLTQTQFGLWSALAIHDTSSVVGSTLQYGPESLQVGTTVKLARALWIVPVTFLIGLFYFRGQKVEGGAGKAKKPWFILGFLIAAALVTWIPELRPVGHVVETVAKRALVVTLFLIGANLTKETLKSVGIKPFLQGVGLWIVVASCTLGAILIGWIH
What are the official names of this protein?
UPF0324 membrane protein Bd1437.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HBL_TRETO
Sequence: MSSSEVDKVFTEEQEALVVKSWAVMKKNSAELGLKFFLKIFEIAPSAKNLFSYLKDSPIPLEQNPKLKPHAMTVFVMTCESAVQLRKAGKVTVRESNLKRLGAIHFKNGVVNEHFETRFALLETIKEAVPEMWSPEMKNAWGEAYDQLVAAIKSEMKPSST
What is the function of this protein?
May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule.
What are the official names of this protein?
Non-symbiotic hemoglobin, TREto GLB1.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: PHND2_PROM0
Sequence: MKLKSLLSVFTISIVALTSACSTKNAGPSADPDKLIVALIPDENAATVIQDNQGLKDYLTEAFDKEIELVVTTDYSSMIEAARNDRLDLAYFGPLSYVLAKAVSDIEPFAARIKGGTKTYNSCIIGNTKKGVTSFDDIKGTTFALGDPASTSSRLFPELTLAENGLTKGKDFQGVFLGSHDAVALAVQNGNAQAGGMACPILKSLKKKGVIDPSKVTTIAQSSPIPQYPWTMRSTLSPELKEKIRFTFLDLDSDKVLKPFNADGFASITDSDYDGIRKAGKLLGLDLSKFVK
What is the function of this protein?
Probably part of the ABC transporter complex PhnC2D2E2.  Binds strongly to methylphosphonate (MPn), ethylphosphonate (EPn) and inorganic phosphite.
What are the official names of this protein?
Probable ABC transporter phosphonate/phosphite binding protein PhnD2.
What is the protein family that this protein belongs to?
Belongs to the phosphate/phosphite/phosphonate binding protein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SNAAL_LYCMC
Sequence: LILVACLMMSCVHCKKDGYPVDWNNCMYDCGYDNAYCEKICKEKGGESGYCYFWKISCYCEGLPDNVEIKGYGRCRG
What is the function of this protein?
Binds voltage-independently at site-3 of voltage-gated sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin LmNaTx21.1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RT25_SCLS1
Sequence: MRGLNLKPSRVYQTAAALLESESISQAPPWYKTIGSVPPSEILTRTQPVQHRGSNGRPRTKKASKLFKPQTIVYEEDRIRQEFFRDHPWELARPRIVLENDGRDGQRCDWTRKEFYALRQEEEIERRIAKEEAEYVGAYFHKGALEVGMELEDKSYEDWKAWATKEVEAANLLKQGAYTGVGAESEDADVLDEAAEADEGVEEPATVVA
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL24E_METS5
Sequence: MVVSHKCSFCGGDIPPATGMMHVRNDGTILWFCSNKCRKYMLKYHKDAKKLKWTTSYSRVR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: ISPF_ECOBW
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PAND_DEHMC
Sequence: MLKSKIHRATITDACIDYEGSITIDKNLMQAANLLPYEQVHVVNVNNGTRLETYVIEGSAGSGQICLNGAAARMGMKGDKIIILGYSLITEEDTLIHQPNLVYVDALNRITKVKNGVANQGLEV
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEP3_EBVA8
Sequence: MGALWSLCRRRVNSIGDVDGGIINLYNDYEEFNLETTKLIAAEEGRACGETNEGLEYDEDSENDELLFLPNKKPN
What is the function of this protein?
Plays an important role in the cytoplasmic envelopment of tegument proteins and capsids during the assembly and egress processes.  Participates also in viral entry at the fusion step probably by regulating the core fusion machinery.
What are the official names of this protein?
Cytoplasmic envelopment protein 3.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 3 family.
What are the subcellular locations of this protein?
Virion tegument. Virion membrane; Lipid-anchor. Host cell membrane; Lipid-anchor; Cytoplasmic side. Host Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Note=Virion membrane-associated tegument protein. Associates with host membrane lipids rafts. During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: MOBA_STAA9
Sequence: MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNIYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_KLEP7
Sequence: MKYVGAHVSASGGLANAAIRAAEIEATAFALFTKNQRQWRAAPLSDETIAEFKAACEKYHFGPGQILPHDSYLINLGHPVEEALEKSRDAFIDEMTRCQQLGLTLLNFHPGSHLQQIPEEECLARIAESINIALAKTEGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRSAEACEKTFAAFERIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDCFSWIMQDSRFDGIPLILETINPDIWAEEIAWLRAQQIAEVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: FABZ_RHOPT
Sequence: MESPIRFENVDINTILKTLPHRFPFLLIDRVINIREDYSGIGIKNVTVNEPAFQGHFPERPVYPGVLMIEGMAQTAGVIGILSVTGTEKPRAVYFLTIDKCKFRKPVMPGDTVEYHLTRTGRRKTMWWFHGEAKVDGQIVAEADVGAMLAD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_PELUB
Sequence: MSLINLAFKKVKTEKRPALLTYTVAGDSTKKKSLEILKSIAKYADICEIGFPHNTPIADGGQIQSSAYRALKNGIKIKDVFSIVKNFKKSKQSKPVILMGYYNMIYQYGDNNFINICKKVGVDGLIVVDLPYPENKEFAKKCKKKDISFIQLVSPTTSLDRMKKIIRDSHDMVYYISMLSTTGGKLKVSPKKILERYGKIKKLNKNKNIVIGFGITEKTIASLRKADGLVVGSALCKEISNSIKKRQNPVTNVTNIVLKLRKKIS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ARAD_HALH5
Sequence: MLEQLKETVFKANLYLPKYQLVTFTWGNVSGIDREKGLVVIKPSGVEYFEMKSKDMVVVDLEGNIVEGDLKPSSDTPTHLALYRAFDKVGGIVHTHSVWATAWAQAGKEIPAYGTTHADYFHGTIPCTRPMTETEILGDYEKETGNVIVETFRNKDPMSIPGVLVHSHAPFVWGKDPMEAVHHAVVLEEVAKMAQKTLSISERTLPMDSVLLDRHFYRKHGQAAYYGQEKR
What is the function of this protein?
Involved in the degradation of L-arabinose.  Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
What are the official names of this protein?
L-ribulose-5-phosphate 4-epimerase, Phosphoribulose isomerase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: CYC_MANSE
Sequence: MGVPAGDVEKGKKLFVQRCAQCHTVEAGGKHKIGPNLHGFFGRKTGQAPGFSYSDANKAKGITWNEDTLFEYLENPKKYIPGTKMVFAGLKKANERADLIAYLKQATK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: IDI2_PELPB
Sequence: MSETANSRTTERKQDHIEICLHGDVVFNGKTTGFERFAFEHAALPEISFSDIDLSTSFLGKSIGAPLMISSMTGGYSEAATLNQRLAEAAERFGIPLGVGSMRQALENRSYRESFAVVRKYAPTVQIFANIGAPEVAKGLTESEINTMLELLRADGLIVHLNAAQELFQPEGNTDFRHVLEQLALLSAKIPVPVLVKEVGCGISASAARQLIAAGVKAIDVAGAGGISWQKVEEIRYTRQFGQERRFSLQALDELLNWGIPTAQCLIDIGALKKESPGLNGIEIVASGGVGSGMDVAKSLALGAQLAASARALLKALHDGVLEETITSWLNDLRAVMFLTGTATIAELRHKTLITKP
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_CLAM3
Sequence: MSKRTFQPNNRKKAKKHGFRLRMRTRAGRAILAARRGKGRTELSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CFI3_ARATH
Sequence: MGTEMVMVHEVPFPPQIITSKPLSLLGQGITDIEIHFLQVKFTAIGVYLDPSDVKTHLDNWKGKTGKELAGDDDFFDALASAEMEKVIRVVVIKEIKGAQYGVQLENTVRDRLAEEDKYEEEEETELEKVVGFFQSKYFKANSVITYHFSAKDGICEIGFETEGKEEEKLKVENANVVGMMQRWYLSGSRGVSPSTIVSIADSISAVLT
What is the function of this protein?
Involved in anthocyanin biosynthesis.
What are the official names of this protein?
Probable chalcone--flavanone isomerase 3, Chalcone isomerase 3, Chalcone isomerase-like 1.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.
Protein: NRDI_SALCH
Sequence: MSALVYFSSSSENTHRFMQRLGLPATRIPLNERERIQVDEPYILVVPSYGGGGMAGAVPRQVIRFLNDEHNRARIRGVIASGNRNFGDAWGCAGDVIAQKCGVPWLYRFELMGTQRDIDNVRKGVNEFWQQLPRSA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: KCY_LACLM
Sequence: MKKIQIAIDGPASSGKSTVAKIIARNLGLIYLDTGAMYRVATLVALQEKTEDASKIIQFIENHPISFANGKNGQEVLVGLDNVTEVIRTNEVTNAVSKISAMMEIREFMVAEQQRIAQKGGIIMDGRDIGTVVLPQANLKIFLVASVDERAERRYKENLSKGIPTDLDRLKVEIAERDRKDSTRAVSPLKQAEDAILLDSTGKTIKEIVQFIEEKAKKLM
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_KOCRD
Sequence: MRVTVLDHPLVAHKLSVLREKDTPSPVFRQLVEELVTLLAYEATRDVRVEPVTIQTPVAETQGTALTRPRPLVVPILRAGLGMLEGMTHLIPTAEVGFLGMARDDATLDIITYAERLPDDLTGRQVYVLDPMLATGGTLSEAIKFLYRRGAQDITCVCLLAAPEGLDRLEKELGDSEVNVVLASVDERLDENAYIVPGLGDAGDRLYGVVD
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: G3P_PYRHO
Sequence: MKVKVGVNGYGTIGKRVAYAVTKQDDMELIGITKTKPDFEAYRAKELGIPVYAASEEFIPRFEKEGFEVAGTLNDLLEKVDIIVDATPGGIGAKNKPLYEKAGVKAIFQGGEKADVAEVSFVAQANYEAALGKNYVRVVSCNTTGLVRTLSAIREYADYVYAVMIRRAADPNDTKRGPINAIKPTVEVPSHHGPDVQTVIPINIETMAFVVPTTLMHVHSVMVELKKPLTKDDVIDIFENTTRVLLFEKEKGFDSTAQIIEFARDLHREWNNLYEIAVWKESINIKGNRLFYIQAVHQESDVIPENIDAIRAMFELADKWDSIKKTNKSLGILK
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADPP_ECOLI
Sequence: MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQMSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEGESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLADENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA
What is the function of this protein?
Acts on ADP-mannose and ADP-glucose as well as ADP-ribose.  Prevents glycogen biosynthesis.  The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
What are the official names of this protein?
ADP-ribose pyrophosphatase, ADP-ribose diphosphatase, ADP-ribose phosphohydrolase, ASPPase, Adenosine diphosphoribose pyrophosphatase, ADPR-PPase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudF subfamily.
Protein: FADA6_MYCTU
Sequence: MPRVDDDAVGVPLTGNGRGAVMTEAYVIDAVRTAVGKRGGALAGIHPVDLGALAWRGLLDRTDIDPAAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQAISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNESKQWLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAGHFENEIITVETESGPFRVDEGPRESSLEKMAGLQPLVEGGRLTAAMASQISDGASAVLLASERAVKDHGLRPRARIHHISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINEAFAPVVMAWLKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELERIGGRYGLQTMCEGGGTANVTIIERL
What is the function of this protein?
May be involved in the final steps of cholesterol and steroid degradation (PubMed:28377529).  Catalyzes the formation of 4-methyl-5-oxo-octanedioyl-CoA (MOODA-CoA) and acetyl-CoA from 6-methyl-3,7-dioxodecanedioyl-CoA (MeDODA-CoA) and coenzyme A (Probable).
What are the official names of this protein?
Steroid 3-ketoacyl-CoA thiolase FadA6, Acetyl-CoA acetyltransferase FadA6.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: DLD_ANAHA
Sequence: MSEYQYNKVTPEMIEKFKEIAPKRVLVGDEINEDFTHDEMAIYGKARPEVLVEATSTEEVAAVVKLCNENKIPVTPSGARTGLVGGAVSIGGGVMISLTKMNKILGYDKENFVVKIQSGVLLNDLAQDAEKQGLLYPPDPGEKFATVGGNVATNAGGMRAVKYGCTRDYVRAMTVVLPTGEIVKLGATVSKTSSGYSLLNLMIGSEGTLGIITELTLKVIPAPKSVISLIIPYENLEDCIATVPQFFMHHLAPQALEFMEKEVVMDTEKFLGKQVYPKELEGTEIGAYLLATFDGNSEEQLEDIIEQASEVVLEAGAIDVLVADTPALKKDAWAVRGALLEAIEADTVLLDECDVVVPTNKIAEFLTYTKSLEAEADFRVKSFGHAGDGNLHIYTCSNDMEEGEFKKQVAVFMDKVYAKATEFGGMISGEHGIGHGKMDYLAESLGPVQMRIMEGVKEVFDPNMILNPGKICYKL
What is the function of this protein?
Catalyzes the dehydrogenation of (R)-lactate (D-lactate) to pyruvate.  Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCPIP), but not with NAD, NADP, or cytochrome c.  Also displays a very low oxidase activity in vitro on D-lactate and L-lactate with O2 as the electron acceptor, but this activity is most likely not physiological.
What are the official names of this protein?
D-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
Protein: IF12_BURVG
Sequence: MAKEELLELDGIVDEVLPDSKYRVTLENGVVVGAYASGRMRKNHIRILAGDRVTLELSVYDLTKGRINFRHKDANSPRPPRAGQARR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.