PharMolix/UniProtQA huggingface dataset:
Protein: DER_CORGL
Sequence: MDVEGAFADEEELAPHGGWASADFDPAEFGYEDSDDDFDAEDFDETEFSNPDFGEDYSDEDWEEIETAFGFDPSHLEEALCTVAIVGRPNVGKSTLVNRFIGRREAVVEDFPGVTRDRISYISDWGGHRFWVQDTGGWDPNVKGIHASIAQQAEVAMSTADVIVFVVDTKVGITETDSVMAAKLLRSEVPVILVANKFDSDSQWADMAEFYSLGLGDPYPVSAQHGRGGADVLDKVLELFPEEPRSKSIVEGPRRVALVGKPNVGKSSLLNKFAGETRSVVDNVAGTTVDPVDSLIQLDQKLWKFVDTAGLRKKVKTASGHEYYASLRTHGAIDAAELCVLLIDSSEPITEQDQRVLAMITDAGKALVIAFNKWDLMDEDRRIDLDRELDLQLAHVPWAKRINISAKTGRALQRLEPAMLEALDNWDRRISTGQLNTWLREAIAANPPPMRGGRLPRVLFATQASTQPPVIVLFTTGFLEAGYRRYLERKFRERFGFEGTPVRIAVRVRERRGKGGNKQ
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ARL8B_BOVIN
Sequence: MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFQSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS
What is the function of this protein?
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.  In its active state, binds to a variety of effector proteins playing a key role in the regulation of lysosomal positioning which is important for nutrient sensing, natural killer cell-mediated cytotoxicity and antigen presentation.  Along with its effectors, orchestrates lysosomal transport and fusion.  Localizes specifically to lysosomal membranes and mediates anterograde lysosomal motility by recruiting PLEKHM2, which in turn recruits the motor protein kinesin-1 on lysosomes.  Required for lysosomal and cytolytic granule exocytosis.  Critical factor involved in NK cell-mediated cytotoxicity.  Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells (By similarity).  In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity).  Also acts as a regulator of endosome to lysosome trafficking pathways of special significance for host defense.  Regulates cargo trafficking to lysosomes by binding to PLEKHM1 and recruiting the HOPS subunit VPS41, resulting in functional assembly of the HOPS complex on lysosomal membranes.  Plays an important role in cargo delivery to lysosomes for antigen presentation and microbial killing.  Directs the intersection of CD1d with lipid antigens in lysosomes, and plays a role in intersecting phagosomes with lysosomes to generate phagolysosomes that kill microbes (By similarity).  Involved in the process of MHC II presentation.  Regulates the delivery of antigens to lysosomes and the formation of MHC II-peptide complexes through the recruitment of the HOPS complex to lysosomes allowing the fusion of late endosomes to lysosomes (By similarity).  May play a role in chromosome segregation (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 8B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Late endosome membrane. Lysosome membrane. Cytoplasm, cytoskeleton, spindle. Cell projection, axon. Synapse. Cytolytic granule membrane. Note=GTP- bound form resides on lysosomal membranes, whereas GDP-bound form is likely associated with microtubular structures. Localizes with microtubules at the spindle mid-zone during mitosis (By similarity). In dendritic cells, localizes to MHC II+ compartments (By similarity).
Protein: CHIT_NPVAC
Sequence: MLYKLLNVLWLVAVSNAIPGTPVIDWADRNYALVEINYEATAYENLIKPKEQVDVQVSWNVWNGDIGDIAYVLFDEQQVWKGDAESKRATIKVLVSGQFNMRVKLCNEDGCSVSDPVLVKVADTDGGHLAPLEYTWLENNKPGRREDKIVAAYFVEWGVYGRNFPVDKVPLPNLSHLLYGFIPICGGDGINDALKTIPGSFESLQRSCKGREDFKVAIHDPWAAVQKPQKGVSAWNEPYKGNFGQLMAAKLANPHLKILPSIGGWTLSDPFYFMHDVEKRNVFVDSVKEFLQVWKFFDGVDIDWEFPGGKGANPSLGDADGDAKTYILLLEELRAMLDDLEAQTGRVYELTSAISAGYDKIAVVNYAEAQKSLGKIFLMSYDFKGAWSNTDLGYQTTVYAPSWNSEELYTTHYAVDALLKQGVDPNKIIVGVAMYGRGWTGVTNYTNDNYFSGTGNGPGSGTWEDGVVDYRQIQKDLNNYVYTFDSAAQASYVFDKSKGDLISFDSVDSVLGKVKYVDRNKLGGLFAWEIDADNGDLLNAINAQFKPKDEL
What is the function of this protein?
Plays a role in host liquefaction to facilitate horizontal transmission of the virus by hydrolyzing beta-chitin and by regulating the cysteine protease VCATH.  Localized in the host reticulum endoplasmic via its KDEL motif, interacts with and thus prevents VCATH secretion before host cell lysis occurs.
What are the official names of this protein?
Chitinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Host endoplasmic reticulum lumen.
Protein: PNO1_YEAST
Sequence: MVAPTALKKATVTPVSGQDGGSSRIIGINNTESIDEDDDDDVLLDDSDNNTAKEEVEGEEGSRKTHESKTVVVDDQGKPRFTSASKTQGNKIKFESRKIMVPPHRMTPLRNSWTKIYPPLVEHLKLQVRMNLKTKSVELRTNPKFTTDPGALQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEVKDVKTLTGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMARESVVSLILGSPPGKVYGNLRTVASRLKERY
What is the function of this protein?
Required for small ribosomal subunit (SSU) synthesis.  Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.  Recruits DIM1 to nucleolar pre-RNAs.  Indirectly required for cleavage at the A2 site of the 20S pre-rRNA, forming 18S rRNA, and at A1 and A2 sites of other pre-rRNAs.
What are the official names of this protein?
Pre-rRNA-processing protein PNO1, Partner of NOB1, Ribosomal RNA-processing protein 20.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: OTC_SULNB
Sequence: MRHFLTLKDFNKEELLEMIALAQKIKAQTKQKQFVPYLERQTLGMIFEKSSTRTRVSFETGIYQLGGIGLFLSANDIQLGRGEPMKDTSRVISRMVDMVMIRTFEQSKLEEFAAYSKVPVINGLTDSYHPVQLMTDYLTMIEFGKADDPICAYVGDGNNMTHSWLMLAAKLGFELRVATPKGYECDPDIVADAMEIAKESGAKITFGNDPKEAVKGCDVVTTDTWVSMGQEDEKEIRLKAFEGYMVDEAMMSLAKSDAIFLHCLPAYRGYEVSEETFEKHAEVIFTEAENRLHAQKGIMVWLDQHC
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_MYCSM
Sequence: MSADKVTLADLPLRDNLRGKSPYGAPQLQVPVRLNTNENPHPPSKALVDDVAASVREAAAELHRYPDRDAVALRTDLAAYLTAATGVRLGVENLWAANGSNEILQQLLQAFGGPGRTAIGFVPSYSMHPIISDGTQTEWLQASRAEDFGLDIDVAVSAVTERKPDVVFVTSPNNPSGQSVPLDDLRRVLDAMQGGILIVDEAYGEFSSQPSAVALLDDY
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RL15E_METM6
Sequence: MSMYNYVKEAWKVPANSYVKELQWSRMQDWRKEPSVIRVERPTRIDRARNLGYKAKQGIVVVRVSVRRGGLRKPRPKHSKKPSTLGINKITMAKSIQRIAEERAAKKYPNLEVLNSYWVGQDGKQKWYEVILVDSCHPSIKSDKSYNWLCKGTHKGRATRGLTSAGKKGRGLMYKGKGAEKVRPSVRANSKKAK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: RRG9_YEAS2
Sequence: MNILRIACRSFHCLRCGPLLNENRGWSSKKIIKLVNKSSLSNKEFTEKVRDGTKDIPEWKKQKMAVRKKLQGQRWNPPKKISQEQMEALRLLKFNFPELTASDLADRFKISPEAVRRILKSNWKRTDEENNNTYERWKRRGERIKEMYQRKEDADFVSNQIVTSRKIILGSNSNSPELIARNVRTFKPFKPNNSTPEKKNTNKLYILKHLGSKQ
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
Protein: METK_ACTP2
Sequence: MAINLFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAWVDIENLTRQVICDIGYTHSDMGFDAHSCAVLNAIGKQSPDINQGVDRADPLEQGAGDQGIMFGYATNETDVLMPAPITYAHRLMEQQAKVRKSGKLDWLRPDAKSQLTFAYENNKIVGIDAVVLSTQHAEHVSQKDLVEGVMEEIIKPVLPSEWLSQNTKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQLSYAIGVADPTSIMVETFGTGRVSNETLVKLIYQNFDLRPYGLIKMLDLIQPIYRETAAYGHFGREHFPWEQTDKAEALRAGAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_DESOH
Sequence: MQVILMETVEALGLAGTEVKVAPGYARNFLFPRQKAMAATPANRRRMEQMRAKIELQIAKERGAAQEAAKKLEGVVCRISAKVSNEGRLYGSVTVGDIVEALAARDITVSKKMVLLRENIKEVGTYPVGIYLYKDVVPEISVEIVADEKAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GLGB_ECOL6
Sequence: MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICSLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPIYRQYHHDKLTFGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGAVHSDEIASHGRQHSLSLTLPPLATIWLVREAE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: INSO1_ECOLI
Sequence: MATLCHVFGVHRSSYKYWKNRPEKPDGRRAVLRSQVLELHGISHGSAGARSIATMATQRGYQMGRWLAGRLMKELGLVSCQQPTHRYKRGGHEHVAIPNHLERQFAVTEPNQVWCGDVTYSVPGVQGGHGCLNEPRVCLEY
What are the official names of this protein?
Putative transposase InsO for insertion sequence element IS911A.
Protein: ISCS_ECO45
Sequence: MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.  Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHH1_CRYNJ
Sequence: MASSSTLLNDDWKQGLAAPPKDLRPQTEDVTATQGSRFEDFGLRRELLMGIYTAGFERPSPIQEQAIPMALTGRDILARAKNGTGKTASFIIPTLNRINTSLSHIQALILVPTRELALQTSQVCKTLGAHIPNLQVMITTGGTTLRDDILRLQQPVHILVGTPGRILDLGSKGIASLNKCGVFVMDEADKLLSEDFMPVIEQTLALCPQERQVMLFSATFPWTVKEFKDQHMVQPYEINLMDELTLKGVTQYYAYVEESQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKVTELGYSCFYSHAKMQQAHRNRVFHDFRNGMTRNLVCSDLLTRGIDIQAVNVVINFDFPRTAESYLHRIGRSGRFGHLGLAISLLTLEDRHNLYRIESELGTEIAPIPAVIDPVLYVAPAMVEEERESPPPKPAAIAAPPAQQQPQQRQRQHPPVPSHQAAQQSPAAAPVQQQQQQQQQQQQQQQQQQPQYQQAYGQGPPQPQALFQQQPNSSPAPAPLPSYSQQAPTQAQGPAPVQSPPPAPSTQPQAPAQTPIQGQIPPTQPRAQQQGQQQPGQPGQAQGQSQPNRRPNTGGFRGNGRGQGHRGRGRGRGGQPGQPGAGAGAGQSQQAQA
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.  Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs.  May also have a role in translation and mRNA nuclear export (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DHH1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: B8_HHV6Z
Sequence: MIYKKVHDEQKSLFFHKFKCQWVPRLGSFLPKRVRTLKIANGATAASVFHQKVKGQWVPRLGSFLPKRVRTLKIANGATAVSVFPHKVKGQWVPRLGSFLPKRVRTLKIANWATAVSVSLHTVKGQWVPRLGSFLLKWVRTLKFANGATAVSVFSDKAKDQWVPRLKFFLPIRMRTLKAVNKATAFPVFPHKLKGQWELRLKSFLIMRMRTLKSANKATTVPVFLHKVKDQWVPRLKYFLPIRMRTLKDANKATAVPVFPHKLKG
What are the official names of this protein?
Protein B8.
Protein: LPTB_SHIFL
Sequence: MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLGEDFRL
What is the function of this protein?
Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Lipopolysaccharide export system ATP-binding protein LptB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PURA_THEAC
Sequence: MVVPNGEGDKTAAVVGLQFGDEGKGKITDYLSGSYDVVVRFNGGTNAGHTVVTDEGTFKFHLLPSGSLRTSYVVLGSGMVIDPVALIPEIEIVRKINPALKIIISRNAHVVTKMHRQIDVEEEKIRSSLMIGTTAQGIGPTYEDKYARTGIRMVDISDIDLIKEKIETMYRMHSNLLANTEFSNLAKREEMAKEIYEAGIKLTGYLDYTEVAIDRLYSQGKRILFEGAQGVFLDPDFGFYPFVTSSNTISASVYTGTGFSLRKVNRIIGVAKAYVSKVGEGPFPTEITGDLAKQLRDLGGEYGTTTGRPRRVGWLDLPMLKYAVRIDDVDEIAITKVDTLGMLDTVKVCRQYLIDGKPIDYVPRDMNTIKKIEPVYDEFEGWGAISDSISGRKISIDQLPSKLVKYIKYIEDQVGKPIGIISMGKERNRTVRIIK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_FRATW
Sequence: MSTDFILAVDQGTTSSRAIIFDKKGNIRKIAQKEFTQIYPKSGWVEHDAMEIWGTQSGVMREALEFGRVKPDQIAAIGITNQRETVVVWDKETGDPVYNAIVWQCRRTSSICDEIKRDPQFVKYIKENTGLVVDAYFSGTKVKWILDNVEGAREKANAGKLLMGTIDTWLIWNLTRGKVHATDYSNASRTMLFNINSLEWDKKILDYLNIPESMLPEVKNSSEVFGVTDSHTLGGAEIPIAGVAGDQHAALFGHCCFEKGMAKNTYGTGCFALMNVGDKPVYSDEGLLTTIAWAENGKPTYALEGSVFIAGAVIQWIRDGLGLVRSAEDSEYYATKIDSTNGVYLVPAFVGLGTPYWDMYARGTIVGITRDTKREHIIRAALEAIAYQAKDVLECMKEDTGLDLAGLRVDGGAVQNNFLMQFQSDILQSEISKPKINEITGLGAVFLAGLAVGFWKDKQELKSILTTEKVFEPQKDSQAVAHDYRGWKKAVERSKAWAECYS
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: PFKA_ECO7I
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase isozyme 1, ATP-PFK 1, Phosphofructokinase 1, 6-phosphofructokinase isozyme I, Phosphohexokinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAF1_CAEBR
Sequence: MSTSVKHREFVGEPMGDKEVTCIAGIGPTYGTKLTDAGFDKAYVLFGQYLLLKKDEDLFVEWLKETAGVTANHAKSAFNCLNEWAEQFI
What is the function of this protein?
DNA-binding protein which plays an essential role in nuclear envelope formation.  Required for normal chromosome segregation during mitosis.  Associates with the nuclear lamina via its interaction with LEM domain containing proteins emr-1 and lem-2 (By similarity).
What are the official names of this protein?
Barrier-to-autointegration factor 1.
What is the protein family that this protein belongs to?
Belongs to the BAF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS19_METMA
Sequence: MAKKSSSRLPKRKGEYTYRGKTVSELQELSLEEFAELLPSRERRSIKRGFTDGQKKVLHEFKEGKKIRTHHRDMIILPEMIGIAIEVHNGKEFVNVELQPEMIGHRFGEFAPTRSRVNHGSAGVGATRSSKFVPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GSA1_LYSSC
Sequence: MNHAKSEAVHAEALQHIVGGVNSPSRSYKAVGGGSPVAMVRGKGAYFWDVDGNRYIDYLAAYGPIVTGHGHPHIAKAITHAAENGTLFGTPTEYEVTFANMLKEAIPSMDKVRFNNSGTEAVMTTIRVARAYTGRTKIMKFAGCYHGHFDLVLVAAGSGPATLGTPDSAGVTTSTAEEVITVPFNNPEAFTEAMNTWGDEIAAILIEPIVGNFGIVEPNPGFLELVHATAKEKGALTIYDEVITAFRFHYGGAQNLLGLTPDLTALGKVIGGGLPIGAYGGRKEIMDTVAPLGPAYQAGTMAGNPASMQAGIACLEVLQTPGIYDEMDRLGGILEEGILAAAKEHGVTITLNRLKGALTIYFTDVKVENYEQAENSNGEIFGRFFKLMLEQGVNLAPSKYEAWFLTTEHTEADILETIKAVNYAFSQLS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DB118_HYLLA
Sequence: MKLLLLALPMLVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCVPSNEDHRQVPTTSPTPLSDSTPGSIDDILTVRFTTDYFEVSSKKDMVEESEAGWGTQTSLPDVHHSS
What is the function of this protein?
Host defense peptide that exhibits antimicrobial activity against both Gram-negative bacteria, such as E. coli and S. typhimurium, and Gram-positive bacteria, such as S. aureus and B. subtilis (By similarity).  Inhibits cell adhesion of E. coli on intestinal epithelial enterocytes (By similarity).  Causes rapid permeabilization of both the outer and inner membrane of E. coli, leading to morphological alterations on the bacterial surface (By similarity).  Binds to bacterial lipopolysaccharides (LPS) with high affinity, and may thereby be involved in immunoregulation through LPS neutralization (By similarity).  May contribute to epididymal innate immunity and protect the sperm against attack by microorganisms (By similarity).
What are the official names of this protein?
Defensin beta 118, Beta-defensin 118.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSL_COXBU
Sequence: MNTATRVIVAQNVRTRNRTFQITKQGVVIVALVIALLCSAFGVVYFKDLNRRLFIQYQTLQREKAEELIQWGKLLLEQTTWSTQSRVQRIAEQQLGMQLPSAKEVILVNADAMIE
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: GAPD1_XENLA
Sequence: MVKPDIHTLAHHLKQERLYVNSEKQLIQRLNADLLKTAERLYRTSWIAKQQRINLDRLILTSAEASPAECCQHAKVLEDTQFVDGYKQLGFQETAYGEFLNLLRENPRLIASCLVTGEKLNQENAQSVIHTVFTSLYGNCIMQEDESYLLQVLRYLIEFELKESDNPRRLLRKGTCAFSIIFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPAKLIERFSPAQQEKLFGGKGTEAFRQRVQAMVETNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMFKTLSCVEGLEVSEVRSMCTDLLLTCFICPAIVNPEQYGIISDAPINEVARFNLMQVGRLLQQLALTGFEERDSRNKSNLNKFDKSCVAAFLDVVIGGRAVETPPLSSVNLLEGLSRTVVYMTYSQLMSLLGFMRTVISSEQLQEEDRMALENLLATVPQTKPGKSNNDTPYSTPQLSPATTPACKKNRLPIVTRSRSKTNLMETENECSPQEVTPNQPEEVLVISLGTGPQLTPGMMSENEVLNMQLVDGGQGDVPVDESKLHGKPDKTLRFSLCSDNLEGISEEEENPCSTGPSNRSNSVSSLDLEGESVSELGGGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETWSTDVLGSDFDPNIDEDRLQEIAGAAAENMLGSLLCLPGSLLLDPCTISETTSEAWSVEVLPSDSAPDLKQEERLHELESCSGLGSTSDDTEVREVSSRPSTPGLSVVSGISATSEDIPNKTEDLRSECSSDFGGKDSVTSPEAEESVHGPHHITTPPTQSESLLAMFDPLAPASSEVVRPKVHYARPSHPPPDPPVLEGASGGNEARLPMFCSHVFIHTDSEAYRQRHSCPERLVRSRSSDIASSIRRPISDPGWVRRGINEDRELLTGTAVNALINPPQSSSFSPSKDSSRGEPDEKKDSDDERSDRNKPWWKKRFVSAMPKAPIPFRKKEKQEKEREDFVQDRFYVAVDSTSQLGPHSQAAEDILAKYRNAIKRTIPNEGSTMPYEGADPVGDGESLHESPRDEALQNMTSDDLLDSANQVAHPQESAFSYRDAKKKLRLALCSADSVAFPVLSHSTRNGLPDHTDPEDNEIVCFLKVQLAEAINLQDKNLMAQIQETMRCVSRFDSRSCSKILSSLAEDYRKRASYIAYLTRCRQGLQSTQAHLDRLLQRVLRDKEVSTRYFTTVCVRLLLESKENEIHEFIQDFQKLTAADDKTAQVEEFLQSLYGAMAQDVIWQNASEEQLQDAQIAIERSIMNRIFKLAFNPNQDADILRDQVLHEHIKRLSKVVTANHRALQIPEVYLREAPWPSAQTEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEYSVPGADDFVPVLVFVLIKANPTYLLSTVQYISSFYSNRLIGEESYWWMQFTAAVEFIKTIDDRK
What is the function of this protein?
Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking.
What are the official names of this protein?
GTPase-activating protein and VPS9 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the GAPVD1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Endosome.