PharMolix/UniProtQA huggingface dataset:
Protein: RTC1_YEAS2
Sequence: MSLSPHVENASIPKGSTPIPKNRNVSSIGKGEFLGSSSSNNSSFRMNHYSNSGQPSVLDSIRRPNLTPTFSYSNGVYMPESHRTSSFNDSYLPYDKNPYAKTTGSMSNKSNMKIKTKKNAINTNTRKSSGLIYTTKVDKELSSIDKVNDPNINGLVCAGKTHLGLYKFSPSDRSIKCVHDFITPNSNTSTRGTTSLLPKLSKRTRQNKFSTIADVKTGFNNYKNCIAVCNNSTAISIYDLNKSSSIDNPLITSLCEHTRSINSFDFNMVESNLIISGGQDSCVKIWDLRSNKSKSSNRSDISINTASDSIRDVKWMPGYNFASKNDQGSSTYGNLKSGYKFASIHDSGYLLKFDLRQPAQYEKKLNAHTGPGLCLNWHPNQEYIATGGRDGKCCLWFVGDNANAAENTVLNYGNSPSLHAPNTSLNNSGSLAFPKLTINTGYPVTKLKFKPAYSSNIYNSLLGISSMGDEAEVRIYSLARKYIPKHVLLSETPSLGLVWWDENLIFNIDKGTRINGWDINKEPTVLENLSKNTTTWRDLDGNGLLSVDQEIGSYEVVEPELQPTSSTTCKKHPGTIKNPKNGNPENQGIIGGIKKGFSHTGLTSFTPERPPTLKAGPTFSSKSLTLASGASSFNSSSASLTSLTPQTENREEIAIEPPCIITLDIPQIFNNIRLTKIAHSRKKNVISESSSMKNSPVEKFKYLARQLKFSYIREHNVSDSADTAYKNDIENIDVVKNATETHGDNTTTTNNNDDGDDDDDDDDDDDKIIESHLLKKYNFPENNTWATLMNEKVNNKKSKRNSSSSREFDEKDVRSSISSISASRQSHDRSRKIDKNVEAELQEKIQTLVDLISIATHNASVYLSIDDLTNFKIWILIRDSLLWDLKWMTSSQISSDNASNMDANESSDFEAGENLKTGKEFPEEDGAGTSGAESLVEERPQAFRANSDEPSDAEKKPVSKLKEQLKNTEIIPYAQPNEDSDEVLTKLKELQNQRLESRTKMGETVSDDVIIEEDEHEHQEEEQPHDSPTKSAQFHASPIAKSIPILQKREHRKSFIDTFMLHSPNGYNGDTDIGNEDDNISPRFTYNSVSPRSKVSSLQSYATTTSQLETFKKLSSHTAPIIGSPRHAPSRPDSIGREQLSSSLTKKLAKCKKIIADPPWDTKKLIKQLYNQATETGNVVLTVNILFLFQTIYQITEIDIAKDAIAHFLLLLHRYELFGIAADVLKYCPFEDIMGSEGDQSSIRLFCERCGELITNESSKEKLRAEAQQTGNKKIMDKFGYWYCDSCKKKNTSCVLCERPLKKLTMVILPCGHEGHFQCIQEWFLDENEQECPGGCPGVAFI
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RTC1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: ADH2_YEAST
Sequence: MSIPETQKAIIFYESNGKLEHKDIPVPKPKPNELLINVKYSGVCHTDLHAWHGDWPLPTKLPLVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLSGYTHDGSFQEYATADAVQAAHIPQGTDLAEVAPILCAGITVYKALKSANLRAGHWAAISGAAGGLGSLAVQYAKAMGYRVLGIDGGPGKEELFTSLGGEVFIDFTKEKDIVSAVVKATNGGAHGIINVSVSEAAIEASTRYCRANGTVVLVGLPAGAKCSSDVFNHVVKSISIVGSYVGNRADTREALDFFARGLVKSPIKVVGLSSLPEIYEKMEKGQIAGRYVVDTSK
What is the function of this protein?
This isozyme preferentially catalyzes the conversion of ethanol to acetaldehyde.  Acts on a variety of primary unbranched aliphatic alcohols.
What are the official names of this protein?
Alcohol dehydrogenase 2, Alcohol dehydrogenase II, YADH-2.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM11_CHICK
Sequence: MAAWGRRRAGPGSTNSGGGGRERVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV
What is the function of this protein?
Plays a role in mitochondrial morphogenesis.
What are the official names of this protein?
Transmembrane protein 11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the TMEM11 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CECE1_CANTT
Sequence: MKFSKVASFAFLALSSQAALIQHDVIIENIKRDAVLAGSAENNIASSAFTKRESEVDSSEDVQLEKRISFAGIVSSIINQLPSIIQIIGNIIKAGLVKRDDIDDAFALVLAEYPHIVSVFEDAFGDFTEAKRDEAASVGTQILGSFPSILTQVVNGFSKVLDFANSDTFSTGLSILSNFTSIASSFASSLSSVVQNGKRDGVEDIVSMVVRQIPDLIVEASTPFVTNAEKMKRDADVAASLVDNLVKKGLSTAIDTFGAATVASVVSKRQVSSFLSKVLSKA
What is the function of this protein?
Acts as a cytolytic peptide toxin that directly damages host epithelial membranes, triggers a danger response signaling pathway and activates epithelial immunity (PubMed:35073742).  Probably acts similarly to cationic antimicrobial peptide toxins, inducing lesions after binding to target cell membranes and causing an inward current associated with calcium influx (PubMed:35073742).
What are the official names of this protein?
Extent of cell elongation protein 1.
Protein: STUA_LEPMJ
Sequence: MNQMQPYADVHQPHMSTAAHAPASGPPAGLSHYSYPHQPSMMQPQQQQHQYGGQPTGYPYAYNNGVPSQLPASSSMNNALVPSTLQLPAMSAGAPNSSMPGSQSYQSHTFDHTGQVAPPGMKPRVTATLWEDEGSLCFQVEAKGVCVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKTRHVVKIGPMHLKGVWIPFERALEFANKEKITEQLYPLFVHDIGALLYHPSNQTRASVGGAAMAAVDRNRRPDSMQTQQRYMAGPTTSQAPSLHHHHSMTNSVGSAMSQPPHAIQPHPSSGRPSLDRAHTFPTPPTSASSMMGMGNQGSSYEWNGANVQQHPQGNQPLSIDTGLSNARSVPTTPASTPPGAVQQGIPYGSSQSYDGSRPMYSAPPAQPSQYAQGQPMMSYRPDNAYPKTEMAPPSRISDVPEEGEVKASDGMMPQGNEQVAAPPAGGEEENEYTHSSAPYNGNRGPYGYNPNGPPGPMHADHTHLSPEMTGSPHQNGSGRATPRTATNGQAQWGSSYPTPQRQAPPSSNLYNVMSDPRGAPNGNAAHDAYQGPGAVPQYASQGYAPTNGVNSSGKRGRDEEDAETYRPDSVQGDDMGGLKRRKTMEGGAVGQTYAQDPSPGLQRAHTLAAQRARR
What is the function of this protein?
Transcription factor that regulates asexual reproduction (By similarity).  Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).  Regulates the expression of several effector genes (AvrLm1, AvrLm6 and AvrLm4-7) during infection stage (PubMed:25727237).
What are the official names of this protein?
Cell pattern formation-associated protein stuA, Stunted protein A.
What is the protein family that this protein belongs to?
Belongs to the EFG1/PHD1/stuA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LON1_SYNFM
Sequence: MFKLTRNKDEQSGSATFAMPLLPLRDIVVFPSMVVPLFVGRDKSVNALDKAMATDKKIFLAAQTKAKTDTPGESDIYRVGTVANILQILRLPDGTVKVLVEGDFRARISSFIPHPDHFFVSLEGLEESEDESVEIEALRRGVRAAFDAYSKHNKKINQEILDAVAAIDNASRLADTIAAYMPFKLDVKQKLLETLGVAKRLEKLFGQIRSEIEILQTEERIKGRVKKQMEKTQREYYLNEQMRAIQKEMGEKDDFKSELEELEKRIKRKKLSQEAAAKVRAEFKKLKLMSPMSAEATVVRNYIDWILSLPWYEKTRDKLDIDESIRILDEDHYGLEKPKERIIEYLAVQALVKRIKGPILCFVGPPGVGKTSLAKSIARAMNRNFIRLSLGGVRDEAEIRGHRRTYIGAMPGKIIQSLKKVKSNNPVFCLDEVDKMSMDFRGDPSAALLEVLDPEQNFSFNDHYLDLDYDLSEVFFITTANNLHSIPPPLRDRMEIIQIAGYTEFDKLNIGRNFLVAKQCKANGLSLDNIAFSDDMLLYIIRHYTKEAGVRNLEREIASICRKVAKEVVRRGPETRIELTEDLVQEYLGIPKFRYGVAEEKDEIGLAVGLAWTEFGGDILGIETVVMPGKGKVQITGKLGDVMQESAQAALSYVRSRAKRLGIDPDFYQNFDIHVHVPEGAIPKDGPSAGITMATSIVSALARIPVRSDLAMTGEITLRGRVLPIGGLKEKILAAHRALLKTVLIPKDNAKDLKDIPAKILEEIQVELVEHMDDVLRKAMVVPEDRELFHEEEAGAQQAVMFEQKPPAADEIRAH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease 1, ATP-dependent protease La 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPYR_ECOL6
Sequence: MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDRFMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGEDAKLIAVPHTKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAEAAKAEIVASFERAKNK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANTR1_MOUSE
Sequence: MDRAGRLGAGLRGLCVAALVLVCAGHGGRREDGGPACYGGFDLYFILDKSGSVLHHWNEIYYFVEQLAHRFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHEGFERASEQIYYENSQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVRGNGFRHARNVDRVLCSFKINDSVTLNEKPFAVEDTYLLCPAPILKEVGMKAALQVSMNDGLSFISSSVIITTTHCSDGSILAIALLVLFLLLALALLWWFWPLCCTVIIKEVPPPPVEESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNSQPAKYPLNNTYHPSSPPPAPIYTPPPPAPHCPPPAPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPSV
What is the function of this protein?
Plays a role in cell attachment and migration.  Interacts with extracellular matrix proteins and with the actin cytoskeleton.  Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading.  Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
What are the official names of this protein?
Anthrax toxin receptor 1, Tumor endothelial marker 8.
What is the protein family that this protein belongs to?
Belongs to the ATR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia.
Protein: ETKMT_CAEEL
Sequence: MLKPSLNAAAKWMIRNTIVSNESLTPEINLHLITIASPLWMSTPDACPLPDPYWAFYWPGGQGLSRFILDNKPLFQGSEIVDFGAGCGSASISASICGAKKILANDIDRYALLSTKLNFHLNNLRDSKIQYSSINFLDDKNERMSTQFFTDSKNIRKFILLGDMFYDSDFAELLFSWLKKIQDAHMVRVLVGDPDRHPLAESEYLQRYKTKFTKNQLAEFSLPGYVIKEHYGFNTAKVFELKFQ
What is the function of this protein?
Probable methyltransferase.
What are the official names of this protein?
Electron transfer flavoprotein beta subunit lysine methyltransferase homolog, ETFB lysine methyltransferase, ETFB-KMT, Methyltransferase-like protein 20, Protein N-lysine methyltransferase METTL20.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. ETFBKMT family.
Protein: SHLB1_BOVIN
Sequence: MNIMDFNVKKLAADAGTFLSRAVQFTEEKLGQAEKTELDAHLENLLSKAECTKIWTEKIMKQTEVLLQPNPNARIEEFVYEKLDRKAPSRINNPELLGQYMIDAGTEFGPGTAYGNALIKCGETQKRIGTADRELIQTSALNFLTPLRNFIEGDYKTIAKERKLLQNKRLDLDAAKTRLKKAKAAETRASSEQELRITQSEFDRQAEITRLLLEGISSTHAHHLRCLNDFVEAQMTYYAQCYQYMLDLQKQLGSFPSNYHSNNNQTAVAPVPSASSNVIGSSALTSTSSLVITSPSNLTDLKECGGSRRARVLYDYDAANSTELSLLADEVITVFSVVGMDSDWLMGERGNQKGRVPITYLELLN
What is the function of this protein?
May be required for normal outer mitochondrial membrane dynamics.  Required for coatomer-mediated retrograde transport in certain cells.  May recruit other proteins to membranes with high curvature.  May promote membrane fusion.  Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation.  Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy.  Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2).  Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation.  Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (By similarity).
What are the official names of this protein?
Endophilin-B1, SH3 domain-containing GRB2-like protein B1.
What is the protein family that this protein belongs to?
Belongs to the endophilin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane. Midbody. Note=Association with the Golgi apparatus depends on the cell type. Following starvation colocalizes with ATG5 and LC3 autophagy-related protein(s)on autophagosomal membranes.
Protein: TRP1_RHOPR
Sequence: SGPGFMGVR
What is the function of this protein?
Myoactive peptide.  Increases the amplitude and frequency of spontaneous contractions and tonus of hindgut muscle.
What are the official names of this protein?
Tachykinin-related peptide 1, Rhopr-TRP-1.
What are the subcellular locations of this protein?
Secreted.
Protein: TRI35_RAT
Sequence: MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPSCPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCVEDKELLCCACQADARHQEHRVQPIKDTAQDFRAKCKNMEHVLREKAKSFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATVDAMKEESRKKHLLAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPSWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAHFGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI
What is the function of this protein?
E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response.  Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via RIG-I signaling pathway.  Can also catalyze 'Lys-48'-linked polyubiquitination and proteasomal degradation of viral proteins such as influenza virus PB2.  Acts as a negative feedback regulator of TLR7- and TLR9-triggered signaling.  Mechanistically, promotes the 'Lys-48'-linked ubiquitination of IRF7 and induces its degradation via a proteasome-dependent pathway.  Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM35.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.
Protein: TPS1_CANSA
Sequence: MQCIAFHQFASSSSLPIWSSIDNRFTPKTSITSISKPKPKLKSKSNLKSRSRSSTCYSIQCTVVDNPSSTITNNSDRRSANYGPPIWSFDFVQSLPIQYKGESYTSRLNKLEKDVKRMLIGVENSLAQLELIDTIQRLGISYRFENEIISILKEKFTNNNDNPNPNYDLYATALQFRLLRQYGFEVPQEIFNNFKNHKTGEFKANISNDIMGALGLYEASFHGKKGESILEEARIFTTKCLKKYKLMSSSNNNNMTLISLLVNHALEMPLQWRITRSEAKWFIEEIYERKQDMNPTLLEFAKLDFNMLQSTYQEELKVLSRWWKDSKLGEKLPFVRDRLVECFLWQVGVRFEPQFSYFRIMDTKLYVLLTIIDDMHDIYGTLEELQLFTNALQRWDLKELDKLPDYMKTAFYFTYNFTNELAFDVLQEHGFVHIEYFKKLMVELCKHHLQEAKWFYSGYKPTLQEYVENGWLSVGGQVILMHAYFAFTNPVTKEALECLKDGHPNIVRHASIILRLADDLGTLSDELKRGDVPKSIQCYMHDTGASEDEAREHIKYLISESWKEMNNEDGNINSFFSNEFVQVCQNLGRASQFIYQYGDGHASQNNLSKERVLGLIITPIPM
What is the function of this protein?
Involved in monoterpene (C10) olefins biosynthesis.
What are the official names of this protein?
(-)-limonene synthase, chloroplastic, (-)-(4S)-limonene synthase, CsTPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SPEB_BLOFL
Sequence: MCTLMHKHDDSLFSNSFGFLRLPLEFYPYTRHNDWVITGVPFDIATSGRSGSRFGPASIRKASINLAWENCRWPWNFDIRQKLKIIDCGDLIYKSGNVQDFTNILQKHIENLLRFRKKILLLGGDHYITLPVLRAYSKFFGTISIIHFDAHADYYDNNNQYDHGAVILYALHEKLINPNRSVQIGIRTEYDKNFGFTVLDAEYVNTTAVHVLINQIVSVIQNRPVYLTFDIDCLDPSVAPGTGTPVIGGLTTSCALQIIRGFQKLNIIGIDIVEVAPVYDCAQITALAAATLGLEMLYTQVKF
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: A1OB5_LOXVA
Sequence: WIMGHMVNNIKQIDEFVNLGSNAIETDVSFDKKANPEYTYHGTPCDCGRDCLRWEYFNDFVKALRTATTPGNSKYDKLFLVVFDLKTGSLYDYQASEAGTKLAKNLLQHYRNNGNNGGRAYIILSIPNLKHFKLITGFQQTLKGEGHAELLDKVGYDFSGNDDIGDVQKIYEKAGVTGHVWQSDGITNCLLRGFTRINAAVANRDSANGIINKVYYWTVDKRQTTRDTLDANVDGIMTNYPDITVEILNEDAYKTKFRIATYEDNPWETFKE
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LvSicTox-alphaIC1bv, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DLST_ECOLI
Sequence: MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
What is the function of this protein?
Plays a role in L-cysteine detoxification (PubMed:27435271).  May transport both D- and L-serine (By similarity).
What are the official names of this protein?
Probable serine transporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCY_RALSO
Sequence: MSDVAAFTAYPVIAIDGPTASGKGTVAHQIADLLGFHYLDSGSLYRLVAFVSIRENIDDHDVNSLVRIASELDVRFKADHIWLKGEDVSLALRHESVGNQASAIAVHGPVREALRARQRAFLEAPGLVADGRDMGTVIFPEAVLKVFLTASVQARAERRYKQLIAKGFSATVESLSRDLEARDLRDRTRSVAPLRPAEAARLLDSSDMSVDEVVAQVLDWYRQVQGVKAR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAB_SELUN
Sequence: MALRSPKSSRGLSQDPTTRRIWFGIATAHDFESHDGMTEERLYQNIFASHLGQLAIIFLWTSGNLFHVAWQGNSEARIKDPLHVRPIAHAIWDPHFGQPAVEAFARGGGLGPVNIAYPGVYQRWYTIGMRTDQDLYTGAFSLLIVSTLFLVAGWLHLEPKWAPSISWFKNAESRLNHHLSGLFGVSSLARAGHLVHVAIPESRGGHVRWGNLLSASPHPQGLGPLSAGQWGVYARDVDSSSHLFNTSQGAGTAIPTFTGGFHPQTQSPWLTDIAHHHLAIAVVFIIAGHTYRTNFGIGHSIGGALEAHIPPGGRLGRGHQGLYDTINNSLHFQLGLALASLGVVTSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFLTRDYSPERGRGNVLARVLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPVFAQWIQSAHGKASYGFDVLLSSPNDPAFNAGRSIWLPGRLDAIDNNSNSLFLTIGPGDFPVHHAIASGLHTTTLILSKGALDARGSKLMPDKKEFGYGFPCDGPGRGGTCDISAWDAFYPAVFWMLNTIGWVTLHWHWKHITLWQGNVAQLDESSTYLMGWSRDYSWLNSSQLINGYNPFGTNSLSVWAWMFSFGHLVWATGFMFLIPRRGYWQELIETLARAHERTPLANLVRWGDKPVALSIVQARLVGLAHFSVGYIFTYAAFPIPSTAGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: RECF_BACAC
Sequence: MFISEIQLKNYRNYEKLELSFEDKVNVIIGENAQGKTNLMEAIYVLAMAKSHRTSNDRELIRWDEDFGQIKGKLQKRNSSLSLELNISKKGKKAKLNQLEQQKLSQYIGVMNVVMFAPEDLNLVKGSPQVRRRFLDMELGQIAPVYLYELSQYQKVLTQRNHLLKKMQGNSKNEETMLDVFTLQLIEHGTKILRKRFEFLHLLQEWAAPIHRGISRGLEELEIVYKPSVDVSESMDLSKIKEVYYESFQSVKQREIFRGTTLIGPHRDDLQFFVNSKNVQVFGSQGQQRTTALSLKLAEIELIYSEVKEYPILLLDDVLSELDDYRQSHLLNTIQGKVQTFVTTTSVDGIEHETLKEAKTIHVTNGTVDCEIDRA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GB_PSHV1
Sequence: MRVCSEASPRRRQVTMLVSLLLFSAQAGFCARSAAGHSGILSLGDPAASGSALGAAEDVGDITFAEAVNSAAFDTSAIFENKLYACSTPNGASVVRLAQPRKCHKYTDSTNMTEGIAVTFKQNIAPLIFNATLYYKHITTVTTWKGFGLAQITNEYRTRVNIGFGEIKEDIDGKGECVTRAAYNRNKVVYEAYDNDVYGVYKPLVPTLLRSPSTRSFHTTNVTQRRTALGYRTSTTVDCVVEYMQARSVYPYTYFGLATGNTLEISPFYKSSDKHSRYNLYAEDRVYEALGYQARDLETRVLAPPHNRNFVFEDEFTVAWDQMDETTTACTMAKWLEIPEAVRVSYNKSFHFNFKDLTATLVASKTPFNISRLHLGGCVPRIANETIEAIYGKKYKNTHVRSGGIEYYLANGGFLIAFQRLVSNDLAELYLDEAARQNHSAVSRSKRAAPSGGGSILSGPAGDLINTHTSATFAMLQFTYDKIQKHVNMLIGNLLEAWCEMQNRQLVVWHEIKKLNPASLMTSMYGHAVAARLLGDVLAVSKCLEIPIENVVMQDSMRVPGDPSMCYVRPVLVFKYPAAADSEAMRGRVARPANNSDVGGSQQAGEAEAQQHVGVHGQLGEHNEILHGRTLIEPCKASHRRYFLFGANYLLYEDYKFIRQVNASEIEEISSTFVNLDVTLLEDLDFVPLAVYTREELRDVGTLNYDEVVRYNNLYNKMFRDLDTALKFDDGLATLRAIGEFLTNTLGGAGKVLGNVVMGAAAAIISTVSGISSFLANPFAALGIGIAVIVCVIMGLLAFRYVMTLRANPVQTLFPGIIDVGEKARQHATVRKDEDASDKELAERVLRGLEILSFESEVRKRREKAAASAKSTLAKRIGQFLRHRKTSTKDDTRKLLKTFDDEDYYYDDEHL
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: Y721_ACIAD
Sequence: MSGWYEISQAKDGQYRFVLKAGNGEIILTSELYKAKASAENGIASVQKNSSDDARYERLVAKNDKPYFNLKAANHQVIGTSQFYASEQSRDKGIESVKNNGTTATVKDLTG
What are the official names of this protein?
UPF0339 protein ACIAD0721.
What is the protein family that this protein belongs to?
Belongs to the UPF0339 family. Duplicated subfamily.
Protein: VEMP_IBVU4
Sequence: MMNLLNTSLEENGSFLTALYVICEFVALYLLGRALQAFVQAADACCLFWYTWVVVPGAKGTAFVYKHTYGKKLNNPELEAVIVNEFPKNGWNNKNPANFQNGKLHT
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the gammacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.