PharMolix/UniProtQA huggingface dataset:
Protein: CHRY4_GIBZE
Sequence: MARILITGSTDGFGFEAARQLIERKHQVYLHARNQERADEVKTKLPGAAGVLIADLTTVAETRKLADEANAIGTFDAVILNAGLLYGPFRKSDLGVPASVFVNLVSPYIFAALLNPPKRLIFIASVLHHEADTSLKDIFWLERGEKEWKDFPAYCDAKFHVVLLVNAIARRFKDTSVIAVHPGYVPTKLAGQDAPGKMEDGIETYVMLAEGDYDTSLTGVYFDPKKERAQPHALTADLDKQEAVVKACEELTGIKLPSP
What is the function of this protein?
Short-chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of the yellow pigment chrysogine (PubMed:28708398).  Pyruvic acid and anthranilic acid are likely substrates for the nonribosomal peptide synthetase chry1/NRPS14, with pyruvic acid adenylated by the first A domain and anthranilic acid by the second (Probable).  If pyruvic acid and anthranilic acid are merged and released from chry1/NRPS14 by hydrolysis, a subsequent amidation would lead to 2-pyruvoylaminobenzamide (Probable).  This process is probably catalyzed by the amidotransferase chry2 using glutamine as amino donor (Probable).  The dehydrogenase chry5 that has a terminal berberine bridge domain for C-N cyclization could catalyze the cyclization of 2-pyruvoylaminobenzamide to yield acetyl-4(3H)-quinazolidinone (Probable).  A final reduction of acetyl-4(3H)-quinazolidinone catalyzed by the oxidoreductase chry4 would result in chrysogine (Probable).
What are the official names of this protein?
Short-chain dehydrogenase chry4, Chrysogine biosynthesis cluster protein 4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: Y4268_PSEPK
Sequence: MMKGGMAGLMKQAQQMQEKMQKMQEELANAEVTGQSGGGLVSVVMTGRHDVKRVSIDQSLMSTDEDDKEVLEDLIAAALNDAVRKVEQSSQEKMGGMTAGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PP_4268.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ARGC1_LACPL
Sequence: MKVGILGGSGYAGAELYRLLLNHPNFNVTFISSEKYAGKPVEKMLKGFAHNGHSHNLRFNHLDDLPFDLDFVFSALPTGVLPKYVEKILEKTSLIFNVSGDFRFKDATTLQQYYPETLAIESDQILSSYYIPEFSDFDKNANIINLPGCMALASIYAAYPLVKNKLINPNIFVDVKTGSSGAGKSTKETAADRFGNFRLYRAFNHRHLPEIAMALGSSVGKVGFAAYSLDISRGIYASVYSQIKKGVTEVDVKKAYFKTYKSCKFVANLTGKQSVPMLKSTNGTNFAEVKATVHEGQCIAVVSLDNLLKGAAGQAVQAANKYYQLVEDTGLDTLAGMWP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase 1, AGPR 1, N-acetyl-glutamate semialdehyde dehydrogenase 1, NAGSA dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIW_LACE2
Sequence: MKVQTKWFGEIEVSEDKIITFDKGIIGFEDWKKYTLVYDAEKEENISIIWLQAIDEPTLALPVMKPEFVFETYDPVVEDELLKALGDDIQDDNIRVYCALTVPRDITKMTINLKAPIIVDFDTMKGIQLIADNSEYQVRYPIYDILKKEEN
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUF60_BOVIN
Sequence: MATATIALGTDSIKMENGQGTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLATPGLVSPALTLAQPLGALPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSVASETHKAIQDLNGRWFAGRKVVAEVYDQERFDNSDLSA
What is the function of this protein?
DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation.  In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor.  Acts as a transcriptional repressor through the core-TFIIH basal transcription factor.  Represses FUBP1-induced transcriptional activation but not basal transcription.  Decreases ERCC3 helicase activity.  Is also involved in pre-mRNA splicing.  Promotes splicing of an intron with weak 3'-splice site and pyrimidine tract in a cooperative manner with U2AF2.  Involved in apoptosis induction when overexpressed in HeLa cells.  Modulates alternative splicing of several mRNAs.  Binds to relaxed DNA of active promoter regions.  Binds to the pyrimidine tract and 3'-splice site regions of pre-mRNA; binding is enhanced in presence of U2AF2.  Binds to Y5 RNA in association with RO60.  Binds to poly(U) RNA (By similarity).
What are the official names of this protein?
Poly(U)-binding-splicing factor PUF60, 60 kDa poly(U)-binding-splicing factor.
What is the protein family that this protein belongs to?
Belongs to the RRM half pint family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes partially with RO60.
Protein: GR64F_DROME
Sequence: MKILPKLERKLRRLKKRVTRTSLFRKLDLVHESARKKAFQESCETYKNQIENEYEIRNSLPKLSRSDKEAFLSDGSFHQAVGRVLLVAEFFAMMPVKGVTGKHPSDLSFSWRNIRTCFSLLFIASSLANFGLSLFKVLNNPISFNSIKPIIFRGSVLLVLIVALNLARQWPQLMMYWHTVEKDLPQYKTQLTKWKMGHTISMVMLLGMMLSFAEHILSMVSAINYASFCNRTADPIQNYFLRTNDEIFFVTSYSTTLALWGKFQNVFSTFIWNYMDLFVMIVSIGLASKFRQLNDDLRNFKGMNMAPSYWSERRIQYRNICILCDKMDDAISLITMVSFSNNLYFICVQLLRSLNTMPSVAHAVYFYFSLIFLIGRTLAVSLYSSSVHDESRLTLRYLRCVPKESWCPEVKRFTEEVISDEVALTGMKFFHLTRKLVLSVAGTIVTYELVLIQFHEDNDLWDCDQSYYS
What is the function of this protein?
One of the few identified sugar gustatory receptors identified so far and which promotes the starvation-induced increase of feeding motivation.  Required in combination with Gr64a to detect sucrose, maltose, and glucose.
What are the official names of this protein?
Gustatory receptor for sugar taste 64f.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr5a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AZUR_METFK
Sequence: MRNQLLFALAFIPTIAAAASNCEVNVSAGDSMAFNTRSIDIPKSCKEFTVNFAHTGTASKAGMGHNWVLARSADVNDLAKAGVEAGIDKNFIPPNDPRVLAYTPLVGGGEKTSVTFKPSILKDGESYSFYCSFAFHSFMMRGTVKLVD
What is the function of this protein?
Probable electron acceptor for methylamine dehydrogenase.
What are the official names of this protein?
Azurin.
What are the subcellular locations of this protein?
Periplasm.
Protein: VIAA_ECO7I
Sequence: MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKAAITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRLNSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQLGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITELEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGGTDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQYRFHAVAMSAHGKPGIMRIFDHIWRFNTGMRSRLLRRWRR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: ADDA_THEP3
Sequence: MGTKWTEEQKQAITTRGSNLLVAAAAGSGKTAVLVERIINLITDEENPVDIDRLLVVTFTNAAASEMRERIAEALIAILDQNPEDKRLANQLTLLNKATITTIHSFCLEVVRNNFFLLDLDPNFRIGDDTETLLLQLEASEELFEEMYAKEDKDKEGFLTLVESYGGTKDDQDLQDILLRLYGFVRSLPWPEKWLKDVINTFRVEDNFKFETSKWAEVILDSLKVEISGILNTMLVAVDKLKNEAGLEGYFHAFQREAYEIEQLLQYDNWNEFKNHIQAIEFERLPNAGKDANKNVKEEVSNIRKKVKDKIKEIKEKFFSDSVEEIKDEIKALYPIMEALADLILLFDKKYKEKKREKGIIDFNDIEHFALQILTEIDEEGAVNPSEVALHYREKFEEIFVDEYQDSNLIQEEILSIIARENPPNRFMVGDVKQSIYRFRQANPYIFFEKYNSYSLDTGEKNQKILLYKNFRSRIEVIEAINYIFKKIMSKNIGEVNYTEEEKLNYGAEYEIPPEDSVTGGAVELHLIEKQKVEEEVEEKEEEKNEEKDFEEEEEDLIDDIQVEARVVAERIKQLFSQNFMVYDKNIKSYRVVDYRDIVVLLRATDRWAPVFLEELTQAGIPAFADTGTGYFDTTEIKTIISLLQVIDNPMQDIPLLAVLRSPIFSFTEEELIDLRLEDMEKTIYEAIKKASQREDELGEKAKNFLDTLKKWQEKAVYMPVDEFLWYLYKDTGYYSYVAAMPQGVQRQANLRILFERAKQYEETSFKGLFNFINFINRLKVSSGDMGSAKIVGENENVVRIMSIHKSKGLEFPVVIVAGLGKQFNTKDLYQKILYHHFLGLGPEFVDFRRRISYPSIVKEAIKYKIKLEGLSEEMRVLYVALTRAKEKLILVGSARDIKKNVRKWANAAILQEKVSEYDILNGKSYMDWIGAAVIRHKDLEPLREFAGVSLSEEEDASKWEVKLWNKKDVLLEKEKNDKVDVVERLRSLDLDAHYSEFYKEVERRLNYVYPYEKACYLPAKLSVTEVKRILNAEVVDEDTTSIFEREVLKTPIFLEKKKGLTAAEKGIAMHLVMQKLDLDKDLSLEGIKEQIKDMVDREILTEEQAKEVNIHKIEGFFKTSLGERMLSSKNVKREVPFHIKLSSREIYKDLPEEYENEFIQVQGIIDCFFEEEDGLVLIDYKTDYVQEGKVEEIKERYKVQIELYSKALENITGKKVKEKYIYLFFNGNILEY
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: MURC_RHOPT
Sequence: MRLPRHIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASESANVNRLREKGIQIHVGHQADNIKGADVLVVSTAIKRDNPELLAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGDLDPTVINGGIINAYGTNARLGGGDWMVVEADESDGTFLKLPADVAIVTNVDPEHLDHFKTFDAVQDAFRNFVENVPFYGFAVMCIDHPVVQTLVGKIEDRRIITYGENPQADARLLDLAASGGGSTFKVAFRDRKAGTAHEIADLKLPMPGRHNALNATAAIAVAHELGLSDDTIRKALAAFGGVRRRFTKTGEWNGVTIIDDYGHHPVEIAAVLKAARQSTSGKVIAVVQPHRFSRLQSLFEEFCTCFNDADAVIVADVYPAGEAPIEGIDRDHFVLGLRAHGHRDVVALQDSASLAGVVAGLAHSGDYVVCLGAGNITQWAYALPGELKALG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3316_METAC
Sequence: MSKFEVYLDEGGKYRFRLRARNGQIIAVSQGYKSEEGCIKGIQSVKENAPNARIIVLE
What are the official names of this protein?
UPF0339 protein MA_3316.
What is the protein family that this protein belongs to?
Belongs to the UPF0339 family.
Protein: ANR_EISFE
Sequence: MEMDDDEAILLDDIYALASTPNQTIVTSSFPQTVSPGFLARRNEALAMVEVAVQSTILILTVVGNAAVLAMIVSLSRHKDLGRMYTMIGHLSCADLFVAIFNLLPQLLWDVTHRFRGGRVLCKLVKYVQVVAMYASAYVLMSTAVDRYTAICHPMRSHTWTSTTAHYLVIGAWVLALVFAVPQLVIFDYVEVVPGSGVYDCVDHFRPRWTLPVYITWFALAVYVIPLVVLATIYLRICVVVWKSANRKSTPMINVAARTSGATEQPSLDDASVSFNVADGGGVDLDPSGGGGSLSRHAAQLSHRQQQQQANNVVLSRAKTKTVKLTLTVVISYLVCWAPFFVSHIWSAWDPHAPFEGTEMVITLLLGSLNSCINPWIYLAFSDQLRRKVTQCCPRSWGQRPSTLSHDSTDFRSGSRPTHS
What is the function of this protein?
Receptor for annetocin.  Activation by annetocin may induce egg-laying behavior through calcium-dependent signaling.
What are the official names of this protein?
Annetocin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYA_RHIEC
Sequence: MSGVNDIRSTFLDYFKKNGHEIVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGLEKRPYATATTSQKCVRAGGKHNDLDNVGYTARHLTFFEMLGNFSFGDYFKENAIELAWKLVTEGFGLPKHRLLVTVYSEDEEAAALWKKIAGFSDDKIIRIPTSDNFWQMGDTGPCGPCSEIFIDQGENVWGGPPGSPEEDGDRFLEFWNLVFMQFEQTEPGVRNPLPRPSIDTGMGLERMACILQGVQSVFDTDLFRTLTGTIEDTIGVKAEGSASHRVIADHLRSSAFLIADGVLPSNEGRGYVLRRIMRRAMRHAQLLGAKEPLMYKLLPTLVQEMGRAYPELARAEALISETLKLEEGRFRKTLERGLSLLSDATADLDKGDMLDGETAFKLYDTYGFPLDLTQDALRAREIGVDIAGFTDAMQRQKAEARSHWAGSGEKATETIWFELREKHGATEFLGYDTEAAEGVVQAIVRDGAVAAEAKAGDKVQIVVNQTPFYGESGGQMGDAGVISSDHGKIEISDTQKRGEGLFVHLGTVIEGVVRDGDAVAMTVDHARRSRLRANHSATHLLHEALREVLGTHVAQKGSLVAPERLRFDVSHPKPMTPEELKIVEDMANEIVLQNSPVTTRLMSVDDAIAEGAMALFGEKYGDEVRVVSMGTGLHGAKSNKPYSVELCGGTHVSATGQIGLVRILGESAVGAGVRRLEAVTGESAREYLAEQDDRVKTLAASLKVQPSEVLSRVEALIDERRKLEKELADAKRKLAMGGGQGGSGDAVREVAGVKFLGKSISGVDPKDLKGLADEGKTSIGSGVVALIGVSEDGKASAVVAVTPDLVERYSAVDLVRIASVALGGKGGGGRPDMAQAGGPDGSKADEAIEAVALALAG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_BURP6
Sequence: MLYPTEFDVIVVGGGHAGTEAALASARMGAKTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAAATDEGGIQFRILNSSKGPAVRATRAQADRVLYKQAIRRRLENQPNLWLFQQAVDDLMVEGDRVVGAVTQVGVRFRARAVVLTAGTFLDGKIHVGLNHYTGGRAGDPAAVSLSSRLKELNLPQGRLKTGTPPRIDGRTIDFSKLDEQPGDLDPIPVFSFLGRAEQHPQQLPCWVTHTNERTHDIIRSGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEPEGLTTNEFYPNGISTSLPFDVQLALVHSMRGLEQAHILRPGYAIEYDYFDPRALKSSLETKAIGGLFFAGQINGTTGYEEAAAQGLLAGINAGRYAQEKDAWCPRRDQAYLGVLVDDLVTRGVSEPYRMFTSRAEYRLSLREDNADMRLTEIGRELGVVDDVRWDAFNRKRDAVSRETERLRTTWVTPKTLPVDEATALLGKPIDHEYSLAELLRRPGVSYDGVCGLRGGECGPSEPLAEDELLLAQIKEQIEIGIKYQGYIERQAGEIERNGANENTRLPDGIDYTEVRGLSFEVSQKLNQFRPETIGQASRISGMTPAAISLLMVHLKKRGLGRRKGTDSVPGADVQADNTAAQQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMED2_MOUSE
Sequence: MVTLAELLALLAALLATASGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
What is the function of this protein?
Involved in vesicular protein trafficking.  Mainly functions in the early secretory pathway but also in post-Golgi membranes.  Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side.  In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER.  Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1.  In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place.  Involved in trafficking of G protein-coupled receptors (GPCRs).  Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization.  Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting.  Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus.  May also play a role in the biosynthesis of secreted cargo such as eventual processing (By similarity).  Required for morphogenesis of embryo and placenta.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 2, COPI-coated vesicle membrane protein p24, Membrane protein p24A, Sid 394, p24 family protein beta-1, p24beta1.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Cycles between compartments of the early secretatory pathway.
Protein: DNCV_VIBCH
Sequence: MRMTWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAKGIAKAVKKSALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDEFLGLTPRFWTQGSFQYDTLNRPFQPGQEMDIDDGTYMPMPIFESEPKIGHSLLILLVDASLKSLVAENHGWKFEAKQTCGRIKIEAEKTHIDVPMYAIPKDEFQKKQIALEANRSFVKGAIFESYVADSITDDSETYELDSENVNLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWDVGGPSSISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPDSTDEKPLFPPSYKHGPREMDIMSKLERLPEILSSAESADSKSEALKKINMAFGNRVTNSELIVLAKALPAFAQEPSSASKPEKISSTMVSG
What is the function of this protein?
Protects E. coli against phage T2 infection.  When the CBASS operon (capV-dcnV-cap2-cap3) is introduced in E. coli MG1655 there is a more than 10(3) decrease in the efficiency of T2 plaque formation.  Protects 100-fold against phage T5, offers no protection against T7 (PubMed:32544385).  When the 4 gene operon capV-dncV-cap2-cap3 is introduced in E. coli MG1655 there is about 100-fold protection against phages P1 and T2 (PubMed:31533127).
What are the official names of this protein?
Cyclic GMP-AMP synthase, c-GAMP synthase, c-GMP-AMP synthase, 3'3'-cGAMP synthase, Cyclic AMP-GMP synthase, c-AMP-GMP synthase, Dinucleotide cyclase DncV.
What is the protein family that this protein belongs to?
Belongs to the CD-NTase family. A01 subfamily.
Protein: DTD_STRGG
Sequence: MRAVVQRVDGASVSVAGATDDPSAPGVVGEIVGEGLCVLVGVTHDDTPQKAAQLARKLWSVRVLEGEKSCSDVNAPLLVISQFTLYGDARKGRRPTWNAAAPGEVAEPLVDEVVAQLRALGARVETGRFGADMRVSLTNHGPFTVIIEV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_CAMC5
Sequence: MRVDTRKCKGRMMQDLNEIFETIKSVAKEISEVIKYADLGYTTHENATGDTQLKLDVQSDEIITAKFKALSCVKALVSEEKDEILPINTNGKFIIAYDPLDGSSLVDVNFAVGSIFGIYENELKPQNLIAAAYSIYGPRLELVINDKKGTKPKFYRLGKDGNFKFVRELELAQKGKLNATGATQKGWSKTHRNFINELFDEGYRLRYSGAMVSDLHQILLKGGGLFSYPATSDHPNGKLRLLFEVLPFAFIYENAGGTTSDGKSDTLFDVNITKTHQTSPCFFGSASEIALLHKFYGKD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAA_ECO7I
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTSVARDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLDPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTTELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPVGSEWLESVRAYEKAILSQRG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y100_XANAC
Sequence: MDKNRIDGAAKQVKGSVKEAIGRVTGDKSTELEGAAEKNVGKVQRKAGEVADDVRDAVKSTK
What are the official names of this protein?
UPF0337 protein XAC0100.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: F16PA_NOSS1
Sequence: MAKASESLDLSVNESTDKALDRDCTTLSRHVLQQLQSFSADAQDLSALMNRIALAGKLVARRLSRAGLMEGVLGFTGEVNVQGESVKKMDVYANDVFISVFKQSGLVCRLASEEMDEPYYIPENCPIGRYTLLYDPIDGSSNTDTNLSLGSIFSIRQQEGDDSDGQAKDLLTNGRKQIAAGYILYGPSTMLVYTMGTGVHSFTLDPSLGEFILSEENIRIPDHGAVYSVNEGNFWQWEESMREYIRYVHRTEGYTARYSGAMVSDIHRILVQGGVFLYPGTIQNPEGKLRLLYESAPLAFLIQQAGGRATTGLVDILDVVPKKLHQRTPLIIGSKEDVAKVESFIQNGH
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLU_DROWI
Sequence: MALDIDTKNSSSAATGDANTVKANNNSSAASTGNKKTENLVNGNNNSAADGPAAKKKGKKNRNKSPPIATDAETTEAATTTAVTNGHEGEALVNGDAVAPDANANVAANDESESAEQQAAENAASSGELESEDVDLDALHDVGITVNISSPGADIISVQLSSMELVQEIHQLLMDREETCHRTCFSLQLGNNTLDNFAELKTVENLEQGSTIKVVEDPYTMREARIHVRHVRDLLKNLDPTDAYNGIDCTSLTYLNTITQGDLLDKKKTRPDSVDCTPPEYVTPGVKEPPLLPLHPNIKNAKGPQALKVLTTSAWNPPPGPRKLHGDLMYLYVVTMEEKRFHISACSKGFFINQSTDENFNPKPDNPSHLSHSLIDLLSTISPIFRRAFQTIQKRRTLRHAFERVATPYQVYQWASPQLEHTVDAIRAEDAFSSKLGYEEHIPGQTRDWNEELQTTRELPRKTLPERLMRERAIFKVHGDFVTAATRGAMAVIDGNVLAINPGEDSKMQMFIWNNIFFSLGFDVRDHYKELGGDHAAFVAPRYDLHGVRVYNAVDVEGLYTLGTVVIDYRGYRVTAQSIIPGILEREQEQSVVYGSIDFGKTVLSHPKYLELLRQAGKHLKILPHSVLNERDEPVELCSSVECKGIIGNDGRHYILDLLRTFPPDVNFLKLQDVKLSKELTEMGFPIEHRHKLCCLRQELLEAFIEDRYVSFIRIAAVHLQQLNAKKQDEAKEGTKEPASETEKESPPKAITEKEEEESKDQPTVGETKSAEAMVNAIREAQSNMATSNEVQAAEVVKRACAAVGSLKEKEFDFRFNPDVFSPGIRHVDGEEGTSSSIVKQKRLVQDAAEFLVLKQIPTFIKEHLAHSSPPIDGQTLTESLHNNGINVRYLGKVIKMLSQMPRMEYLYRIANLELIVRATKHIYYTYMQGTEPLHLSAAISHFLNCLLTNGPVNPAISKEEIHKKRTNTKYNKHKSSKSSGSGSKQSGQTSNQNGTSTSPSSSTASGGTSSNVAIDWTLVTPRSLWQQIRKEAKAYWDWDLECDAIDIALTKYGISRISLLRGFCQKVGIQVLLREYNFESKHKPTFGDDDIVNVFPVVKHISPRSTDAYNFYTTGQSKIQQGLFKEGYELISEALNLLNNVFGAMHQENGSCLRMLARLSYLLGDAQDALAIQQRAVIMSERVNGIDHPSTILEYTHLSLYSFANGHVGMSLKLLYRARYLLVLICGEDHPEVALIDSNISLILHALGEYELSLRFIEHALKLNLKYFGAKAMHVAVSYHLMARTQSCMGDFRSALNNEKETYTIYKSQLGEKHEKTRDSAECLRLLTQQAVLLQRKMNDIYSNGKLTSDLPPIHITPPSMGSVLDMLNTINGILFVQISQNDIVKVRSEIEKHLKANGEESEVNDAIKSIVDASGNNNGETEALINGGEESTVTVTATS
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Protein clueless, Clustered mitochondria protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TORD_SERP5
Sequence: MPLLNEVARQRAIIYRWFSQLLFQELSDEGLLRLRDKENLALLNALKLIPELSLLVTHFQRRLRAMLKREECRLELAADFASLFLLPAPSGVSPYAGHYPHTNSPEERQALRQKLVEHRLAPQNNEAVDHIAIQLALMTALIEEGVEREQQDLFLNRHLLSWLPLCTKRCYQRDRFGFYAAAMGLLTGFVQQDSEWLIACRLATHPARPGQS
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.