PharMolix/UniProtQA huggingface dataset:
Protein: FBK99_ARATH
Sequence: MSSPVKKMKKKTTTSPILSPTPHSTQILSLPVDLLISILARVSRLDYPILSLVSKSFRSLIASPELYETRSLLGRTESCLYLCLGIPSDFNPRWFTLCRKPKPSGHVMAAISIPNSRPVHCSGLVAVGSDIYNIGGSIINEHSSSVSILDCRYHTWRDAPNMLVERNSHAANVIDGKIYVAGGSRDSNSSNWMEVFDIKTQTWEPVLNPIADGCDRRIRKSAVIEEAICLFGYKGVGVAYNPRIDKWEAIGEVNYLDLGWVWLLVA
What are the official names of this protein?
F-box/kelch-repeat protein At4g39560.
Protein: YCX2_CHLRE
Sequence: MYWSLTACSAVLFCLRDSLIFLADDVNPERGNEGVAVGTGGIPGRGIPPLITANGIGLYTFTSIGLLVPFTLGLKTQNQQIKIVVKSKISETNKLVIFCCLKHIISRKARSWLNDSR
What are the official names of this protein?
Uncharacterized 12.7 kDa protein in 16S rRNA region.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL39_METLZ
Sequence: MSKLTKSRKIRLAKATQQNRRVPAWVMIKTKRTVVSHPKRRNWRRSTLKV
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: RL25_PROMH
Sequence: MLTINATVRKEQGKGASRRLRVANRFPAIVYGGNEEPIAIDLDHNEVINQEHKSEFYADFVNLVIDGKATKVKVKAVQRHEYKPKITHIDFLRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: CLSA_YERE8
Sequence: MTTFYTVISWLSVFGYWLLIAGVTLRILMKRRAVPSAMAWLLVIYILPLVGIIAYLSFGELHLGKRRAERAKAMWPSTARWLSELKDCQHIFASSNSEVATPLFQLCERRQGISGVKGNQLQLLTTTDDTLKALVRDIELARHNIEMVFYIWQPGGLVDQVAESLMAAARRGVHCRLMLDSAGSQQFFRTPYPAMMRNAGIEVVEALKVNVFRVFLRRMDLRQHRKVVLIDNYVAYTGSMNMVDPRFFKQDAGVGQWIDMMARMEGPVATTIGIVYACDWEIETGKRILPPPPDTHIMPFEEESGHTIQVIASGPGFPEEMIHQALLTAVYAARKQLIMTTPYLVPSDDLLHAICTAAQRGVDVSIIVPRDNDSMMVRWASRAFFSELLDAGVKIYQFEGGLLHSKSVLVDGQLSLVGTVNLDMRSLWLNFEITLVIDDDGFGADLAQVQDDYIARSVLLDGEQWNKRPLWHRVTERLFYFFSPFL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METK_STRPI
Sequence: MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAETAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSPDIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRLAELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDKVIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVAESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALKEAVK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_TRIV2
Sequence: MPNSTPQSQLIRVHVFVTGRVQGVGFRYSTVDTASQLGLTGWVRNLPDGRVEAVFEGARDIVEEMVRWCHAGPPAAVVQDVAVEYEEPEGLRGFEVKRLVN
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RL31_RHOPS
Sequence: MKTEIHPNYHSITVVMTDGTEYQTRSTWGKEGDKLNLDIDPRSHPAWTGGTQQVLDRGGRVSRFQKKFSGFLKKD
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PCAI_PSEPU
Sequence: MINKTYESIASAVEGITDGSTIMVGGFGTAGMPSELIDGLIATGARDLTIISNNAGNGEIGLAALLMAGSVRKVVCSFPRQSDSYVFDELYRAGKIELEVVPQGNLAERIAAAGSGIGAFFSPTGYGTLLAEGKETREIDGRMYVLEMPLHADFALIKAHKGDRWGNLTYRKAARNFGPIMAMAAKTAIAQVDQVVELGELDPEHIITPGIFVQRVVAVSGAAASSIAKAI
What are the official names of this protein?
3-oxoadipate CoA-transferase subunit A, Beta-ketoadipate:succinyl-CoA transferase subunit A.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit A family.
Protein: ECOT_SERP5
Sequence: MNKASVVFSGLLMAVSASAIAATSSEDTDISKQPLEKVAPYPKAEKGMSRQVIYLPKQEHEENFKVELLIGKTLEVDCNRHMIGGTLETKTLSGWGYDYLVVEKLSEPASTMMACPDNTKQQKFIAANLGDAAMQRYNSRLPIVVYAPKDVEVKYRVWKAEDTVSKAEQK
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GCSP_SHESH
Sequence: MTTETLTQLEQHELFIRRHIGPDSAQQQEMLNFVGAESLEDLTQQIVPESIRLNRDLAVGSACGEAEGMAYIREIADKNKVFKSYIGMGYYGTEVPSVIQRNVLENPGWYTAYTPYQPEIAQGRLEAILNFQQVSMDLTGLDLASASLLDEATAAAEAMALAKRVSKAKKANIFFVADDVFPQTLDVVKTRAECFGFEIVVGPASEAVNYELFGALFQYTNRFGEITDFTELFTELKAKKAVVSVAADIMSLVMLKSPGSMGADVVFGSAQRFGVPMGLGGPHAAFFVTRDAHKRSLPGRIIGVSQDTRGNRALRMAMQTREQHIRREKANSNICTAQVLLANMASFYAVYHGPQGLKIIAERIHRLTDILASGLTAKGVELVNGTWFDTLSLKATDSEAITARAVAAGINLRIDSDGVLGVSLAETTLREDIAELFDVILGEGHGLDVAALDAEIIKAGSSSIPAQLVRTDAILTHPTFNSYHSETEMMRYIKRLENKDLALNHSMISLGSCTMKLNAATEMMPISWPEFGNMHPFCPLDQSEGYTDLIEELSTWLVDITGYDAMCMQANSGASGEYAGLLAIRNYHISRGDAHRNVCLIPQSAHGTNPASAQMAGMKIVVTACDKAGNVDMEDLKAKAAEVAENLSCIMITYPSTHGVYEETVSEICEVIHQHGGQVYLDGANMNAQVGLTTPGSIGADVSHLNLHKTFAIPHGGGGPGMGPIGVKAHLAPFVAGHVVVKHGRESDNNGAVSAAPYGSASILPITWMYIKLLGHQGLRQSTQVALLNANYVMKKLSEHYPVLYTGRNERVAHECIIDLRPLKESSGVTEMDIAKRLNDYGFHAPTMSFPVAGTLMIEPTESESKVELDRFIEAMISIRGEASRVESGEWPADNNPLHNAPHTLADIMDPEFDSRPYSREVAVFPTAAVKLNKFWPTVNRIDDVFGDRNLFCACVPMSEYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: CSRA_GEOMG
Sequence: MLVLTRKMGETITIGDQIRIKVVEMKGNQVRLGIEAPGDMRIYREEIYLKVQKENQLAAAWSLEDLESAVNFAGAGKE
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_SALPK
Sequence: MQPDLHCRTLAAHTLKHFRALSPLTHCMTNDVVQTFTANTLLALGASPAMVIDPVEARPFAAIANALLINVGTLTASRADAMRAAVESAYDAKTPWTLDPVAVGVLEFRRRFCLDLLSLRPAAIRGNASEILALAGMALGGRGVDTTEAALAALPAAQALARQIDCIVVVTGEIDYVTNSQRTLSIPGGDPLMTRIVGTGCALSAVVAASCALPGAALDNVASACCWMKLAGQAAAERSEGPGSFIPAFLDALYHLDVEAANATN
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: CTDP1_MOUSE
Sequence: MEAPPAAGVPTECTPAVAGAEVRCPGPTPLRLLEWKVAAGATVRIGSVLAVCETAASAQPAGPAPARAASGGCVRAARTERRLRSERAGVVRELCAQPGQVVAPGALLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGRQQVPLSTATVSMVHSVPELMVSSEQAEKLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCPQMSNKGIFHFQLGRGEPMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFPGTGDVNAPPAARETQARRKVNHSSKGGDALEQALSVRDPEDGRPAPGVEHSNGLGKASRELNGGEAVPGVFPSKADEKEAWPLTRASPASSSSGHEPTEAPELPVSCEWDGRTTPGVQPTQGDAATQDLDFDLSSDSESSESSSRSEGQRAPAPQERTKAAPEHSGPQDTSGGRAAASPLGESGPSIHPHDKGSDLDTQEEGERDSLCGLGNGSVDRKEAETESQNSEQSGVTAGESLDQSVGEEEEEDTDDDDHLIHLEEILVRVHTDYYTKYDRYLNKELEEAPDIRKIVPELKSKVLADVAVIFSGLHPTNFPVEKTREHYHATALGAKVLTQLVLSPDAPDRATHLIAARAGTEKVRQAQECKHLHVVSPDWLWSCLERWDKVEEQLFPLIDDDTRTHRDNSPAVFPDRHSVLPTALFHPTPIHSKAHPGPEVRIYDSNTGKLIRMGPQGSAPAPSSAPLNHGEPSSFRAVQPHQQQMFGEELPESQDGEQPGPARRKRQPSMSEAMPLYTLCKEDLESMDKEVDDILGEGSDDSDIEKKKPEDQDNEQERAPKPRKPRAPGIRREQPVGLPSSGERSTPGMRGPRGHKRKLNEEDAASESSGESSNDDEEGSSSEADEMAAALEAELNDLM
What is the function of this protein?
Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit.  This promotes the activity of RNA polymerase II.  Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation (By similarity).
What are the official names of this protein?
RNA polymerase II subunit A C-terminal domain phosphatase, TFIIF-associating CTD phosphatase.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Found at centrosomes in prometaphase, at spindle and spindle poles in metaphase and at spindle midzone and midbody in anaphase and telophase-G1 respectively.
Protein: THIG_XANOM
Sequence: MTTPSPSDALLIAGKRYRSRLLTGTGKFKDLDETRLATEAAAAEIVTVAIRRVNIGQDPNAPSLLDVLPPDRYTLLPNTAGCYSAEDAVRTCRLARELLDGHNLTKLEVLGDERTLYPDVVQTLKAAEQLVADGFEVMVYTSDDPILAKRLEEIGCVAVMPLAAPIGSGLGIQNKYNLLEIIENAKVPIIVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPILMASAMRKAIEAGREAFLAGRIPRKRYASASSPVDGVIG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH3_METST
Sequence: MIQVTLIQIDNYGPWTVTPGPRAEPDLQTLQSRLYGDLEREFGAHGAIVFFNRFDNLIAISNGMDYDDHLLIQQSIRNRYPITISMGVGTADTAYEAQKIATKMIQNGGGAQSANRCEVLNIDSLADDDNSLVQIAHIDINDITNTLTDIETAFDTSIKVYEVLLALMDELAKIGGMCFFIGGDNYMAPTNGISKDQLREALKVVDKKTGVTLKAGIGVAKQAGRAADLADIGLEDIRAELVDDSVLLFNDLDEY
What is the function of this protein?
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP.  Also has an independent pyrophosphate phosphohydrolase activity.
What are the official names of this protein?
GTP cyclohydrolase III.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GTP cyclohydrolase family.
Protein: XERC_LISIN
Sequence: MTQEGQLEKRFLDYLHSERNYSEHTSTAYENDLSDFRRFLNEQAIIEYQQVTFLDVRIYLTELKQKSFSRTTVARKISSLRSFYTFLLRENVITENPFTYVSHAKNQLRLPKFFYSEEMEALFQVVYEDNETLTLRDRVILEVLYGTGIRVSECAGIMLSDLDTSYQAILIRGKGNKERYVPFGAYAEDAITDYLSGRIELMTRFKKTHDSLLINHYGDPLTTRGIRYCLTKIISKASLTRKIHPHMLRHTFATDLLNNGADMRTVQELLGHASLSSTQIYTHVTKEHLKSTYMKHHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ID4_MOUSE
Sequence: MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAARCKAAEAAADEPALCLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETHPALLRQPPPPAPPLHPAGACPVAPPRTPLTALNTDPAGAVNKQGDSILCR
What is the function of this protein?
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity.  Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation.
What are the official names of this protein?
DNA-binding protein inhibitor ID-4, Inhibitor of DNA binding 4, Inhibitor of differentiation 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: IMP4_MOUSE
Sequence: MLRREARLRREYLYRKAREEAQRSVQEKKERVKRALEENQLIPTELRREALALQGSLEFDDAGGEGVTSHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGTMSEAKPHLITHGFSSRLGKRVSDILRYLFPVPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYTNTARKRVFLSAE
What is the function of this protein?
Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP).  Required for the early cleavages during pre-18S ribosomal RNA processing.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
U3 small nucleolar ribonucleoprotein protein IMP4, U3 snoRNP protein IMP4.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: BORC7_DANRE
Sequence: MASSETQPRFGQSVKGLLSDKVTSCSGDVIALTRQVLKGSRSQELLSQAARNMVIQEDAILHSEDSLRKMSIITTHLQYQQEAIQKNVEHSKNLQDQLRHLMK
What is the function of this protein?
As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor.
What are the official names of this protein?
BLOC-1-related complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the BORCS7 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: ENGB_WOLPM
Sequence: MAKQITSNCNFIFGASDIKSLPNESAPEIAFAGRSNVGKSSLINLLINSKKAARVSSKPGCTRQINFYSMYDDKFRLVDLPGYGYSHAGKEEIIQYLNLIEYYLIQRENLRRVFVLIDSKVGLKEIDKDFIYWLIYNNINFNIVLTKIDKVSQKSLGAVIEDIQKWINNENVSIHQMSIRVKHKITKVRDEFFKFTR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ARAG_ECOLI
Sequence: MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGAGKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAENIYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALARNAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKDGRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPISLAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMMLCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPGAEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGVAVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YJ11B_YEAST
Sequence: MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVQYGDFYWVSKRYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDTGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSHYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty1-JR1 Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLB2_GLYDI
Sequence: GLSAAERQVVASCWKDIAGADXGAGVGKEXLIKFISAAPEMAAVF
What are the official names of this protein?
Globin, minor monomeric component.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL11_PIG
Sequence: MAQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKHDGIILPGN
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs.  It also couples ribosome biogenesis to p53/TP53 activation.  As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53.  Promotes nucleolar location of PML.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm.
Protein: LEXA_DECAR
Sequence: MKLTPRQQEILDFIKSTLEVLGAPPTRMEISSAFGFASPNAAEDHLKALAKKGAIVLEPGSARGIRLVEQLGLPLIGSVAAGSPILAVENMQGRYALDASLFAPKADFLLKVRGLSMIDVGIFDGDLLAVHKTNQARDGQIVVARLDEEVTVKRLERSGGQIRLIAENPDFEPIIVDPEAVDFAIEGIAVGLIRGAVSKLS
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: HIS1_HAEIE
Sequence: MTNTTMQPNRLRIALQKKGRLSQDCAILLKQCGVKINWNEQRLIAYAENLPIEILRVRDDDIPGLIFDGVVDLGIIGENVLEEEELGRRAANETVTYKKLRQLDFGDCRLSLAVDRDCHYENVKDLANRRIATSYPYLLKRYMNENGVSFKSCLLNGSVEVAPSAGIAYAICDLVSSGATLEANGLKEVDVIYRSKACLIQRAEPLESTKQALVDKLLTRIQGVQQAAESKYIMLHAPKEKLEKITALLPGVENPTILPLASDTTRVAMHVVSQENLFWETMEQLKEAGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_POLAQ
Sequence: MAKMQTKMQNEERDDGLREKMIAVNRVTKVVKGGRILGFAALTVVGDGDGRIGMGKGKSKEVPVAVQKAMDEARRKMIKVTLRKGTLQHTVTGQHGASRVLISPAKDGTGIIAGGPMRAIFDVMGVTNVVAKSLGSTNPYNLVRATIDGLSKMSTPAEIAAKRGKSVEEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.