PharMolix/UniProtQA huggingface dataset:
Protein: PANC_VARPS
Sequence: MYIAHTIDELRSHLAAFRRPAFVPTMGNLHEGHLALVKQAKPLGDVTVASIFVNRLQFLPHEDFDTYPRTWDSDCEKLRTAGCGVLFAPDEKALYPEPQTCKVHPDPALADILEGHFRPGFFVGVCTVVMKLFQCVQPRVAVFGKKDYQQLMMIRHMVRQFALPIEIVGSETFRADDGLALSSRNGYLSEAERAEAVQLSKALKAMAQAVQAGERDLAAIEARAMQALAQRGWQPDYLVLRRRSDLQAPSSANLAGEPLVALAAARLGGTRLIDNLEIDAMPS
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA_EDWI9
Sequence: MKKSIFTSLYLQVLVAITIGILLGHFYPDLGTQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAIALLYFEVVSTIALIIGLVVVNILQPGVGMNVDPNALDTKAVAVYADQAAQQGIVAFLLDVIPSSVIGAFASGNILQVLLFAVMFGFALHHLGEKGQLIFNVIDSFAKVIFGVINMIMKLAPIGAFGAMAFTIGKYGVGTLVQLGQLILCFYITCALFVVLVLGSIAKATGFSIFRFIAYIKEELLIVLGTSSSESALPRMLDKMEKVGCQKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNAQMDIWHQVTLLVVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLIGNGVATIVVAKRCRQLNEKQMNAVLGGRDSALRDPIA
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIO1_SYNE7
Sequence: MSVAAAVTDATFKQEVLESSIPVLVDFWAPWCGPCRMVAPVVDEIAQQYSDQVKVVKVNTDENPSVASQYGIRSIPTLMIFKDGQRVDTVVGAVPKTTLANTLDKHL
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin 1, Trx-1, Thioredoxin-M.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: DAPF_ACTSZ
Sequence: MHFSKMHGLGNDFVVVDAVTQNVFFPEEVIKKLADRHRGIGFDQLLLVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVTLKGLTNKKDIAVSTAKGRMVLTVKDDGQIRVNMGEPIWEPAKIPFNANKFEKNYILRTDIQTVLCGAVSMGNPHCVIQVEDIKTANVAQLGPLLESHERFPERVNAGFMQVIDRHHIKLRVYERGAGETQACGSGACAAAAVGIMQGLLDSPVQVDLPGGSLIIEWDGEGHPLYMTGDATHIYDGVIKL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REC2_HAEIN
Sequence: MKLNLITLVVLLIVADLTLLFLPQPLLLPWQVALVIALVLIFLFIFLRRNFLVSLAFFVASLGYFHYSALSLSQQAQNITAQKQVVTFKIQEILHQQDYQTLIATATLENNLQEQRIFLNWKAKEVPQLSEIWQAEISLRSLSARLNFGGFDRQQWYFSKGITAVGTVKSAVKIADVSSLRAEKLQQVKKQTEGLSLQGLLIALAFGERAWLDKTTWSIYQQTNTAHLIAISGLHIGLAMGIGFCLARVVQVFFPTRFIHPYFPLVFGVLFALIYAYLAGFSVPTFRAISALVFVLFIQIMRRHYSPIQFFTLVVGFLLFCDPLMPLSVSFWLSCGAVGCLLLWYRYVPFSLFQWKNRPFSPKVRWIFSLFHLQFGLLLFFTPLQLFLFNGLSLSGFLANFMAVPIYSFLLVPLILFAVFTNGTMFSWQLANKLAEGITGLISVFQGNWLTVSFNLALGLTALCAGIFMLIIWNIYREPEISSSNWQIKRAKFFTLNLSKPLLKNERINVLRCSFGIILLCFTILLFKQLSKPTWQVDTLDVGQGLATLIVKNGKGILYDTGSSWRGGSMAELEILPYLQREGIVLEKLILSHDDNDHAGGASTILKAYPNVELITPSRKNYGENYRTFCTAGRDWHWQGLHFQILSPHNVVTRADNSHSCVILVDDGKNSVLLTGDAEAKNEQIFARTLGKIDVLQVGHHGSKTSTSEYLLSQVRPDVAIISSGRWNPWKFPHYSVMERLHRYKSAVENTAVSGQVRVNFFQDRLEIQQARTKFSPWYARVIGLSKE
What is the function of this protein?
Might contribute to transformation as a member of a membrane-bound pore complex at the base of the transformasome.  It could directly interact with transforming DNA during translocation indirectly by participating in the assembly of the pore.
What are the official names of this protein?
Recombination protein 2.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SULA_YERE8
Sequence: MRTQSLKPYNANYHSLITRDAQERVDAPTDSGLISELVYSENQPAVAQLLLPLLQQLGKQSRWLLWLTPQQKLSRLWLQQSGLPMSKVVQARQINPLSTVDAMEKALLTGNYSVVLGWLPELSENDRIRLRMAAKLGNAYGFVMRPLNETKLDQGQCATLKIHSSLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: RK32_ATRBE
Sequence: MAVPKKRTSTSKKRIRKNIWKRKGYWVALKAFSLAKSLSTGNSKSFFVRQTKINK
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYH_MACCJ
Sequence: MMINIPRGTQDILPAETAKWRYVESKLHNIAANYNYKEIRTPMFESTDLFARGVGGSTDIVQKEMYTFKDKGDRSLTLRPEGTAAVVRSYIENKMNGDANQPVKLYYNGPMFRYERKQKGRYRQFVQFGVEAIGSENPAIDAEVIHMVYNIYKSFGLKHIKIVLNSIGDMDSREEYKQALIEHFEPHINNFCNDCKNRLHTNPMRILDCKVDHEQPTVKTAPKITEYLNDYSKNYYEEVKQYLDLLNIPYIEDASLVRGLDYYTHTAFEVMSEAEGFGAITTLCGGGRYNGLLEMLDGPKETGIGFALSIERLLLAIEAEDIQLDVEESVDIFVVTMPETVKEAVKIVAELRNAGIRCDMDYLGRKMKGQMKQADRIHATYTVVLGSNEIETNKIQIKAMQTGESETIKLQDIASYIKGE
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PI4KB_DANRE
Sequence: MGDTELELSPTHLEELQKSPSTSTTSSLSLPSSPSSGPHPLTSSSPSTSEGLPTSSPPLDVISEGLGELSLVIDTEVAKKACQEVLQKVKFLKGDGEVSSASSEPILANGTAHPEANDGGQPPKISEEEVEPIKSVRRRQKNNSSKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFSFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYVVYRCRQSINFSLQCAWLLGAYSSDMHISTQRHSRGTKLRKLILSDELKPSSQRIRREVPQPPPPYPPPLHHGPGMSEHSLSPSKRTHQRSKSDATVSISLSSNLKRTASNPKVETSQDEPVRLTPQREFIKSLMGIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAAFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFETSSVPVRIPETQIRSTRSVENLPDCGITPDQRASSFSTVPNYDNDDEAWSVDDIGELQVELPEIHTNSCDNISQFSVDSITSQESKEPIFIAAGDIRRRLSEQLAHTPTTFRKDPEDPSAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAYQVLKQLQIIWEQERVPLWIKPYKILVISSDSGMIEPVVNAVSIHQVKKQSQLLLLDYFRQEHGNFNTEEFLTAQRNFVQSCAGYCLICYLLQVKDRHNGNILLDSEGHIIHIDFGFILSSSPRNLGFETSAFKLTSEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMEKVIQIVEIMQQGSQLPCFHGSSTIRNLKERFHMNLTEEQLQVLVEQMVDGSMRSITTKLYDGFQYLTNGIM
What is the function of this protein?
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP).
What are the official names of this protein?
Phosphatidylinositol 4-kinase beta, PI4K-beta, PI4Kbeta, PtdIns 4-kinase beta.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
What are the subcellular locations of this protein?
Endomembrane system. Mitochondrion outer membrane; Peripheral membrane protein. Rough endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: UVRC_HYPNA
Sequence: MRGVDVIKENLKHLPSRPGVYRMFGEAGEVLYVGKARDLKARVSNYTRMGGHTQRIARMISLTRAMEFVVTETETEALLLEASLVKSLKPRFNVLLRDDKSFPYILIRRNHEAPQIKKYRGSKQDEGDYFGPFANAGAVMRTLDTLQKAFLLRTCEDSVYSARTRPCMLHQIKRCAAPCVGLVSKEDYTALADEAADFLRGKAGELQKRLASEMEAASEAMEFETAARLRDRIRAIAHVRSTQDVNPDGIEEADVFAIAMDGGVSCVQVFFIRAGQNWGASAHFPRHEKDQTAPEILAAFLVQFYDKRPPPKLILVSEPPDQADLIEEALALKAGRRIELRRPERGTKRDLLTQAERNASEALSRKLAESASQERLLTEVQKVFDLAEAPQRIEVYDNSHIQGTNAVGGMIVAGPEGFRKQAYRKFNIKDTEITPGDDYGMMREVMRRRFARAMKEKVAGNVSDWPDLVLIDGGLGQLNATLETLAELGLTPDDVTLVSIAKGVDRNAGREQFFRPGKAPFKLPENAPVLYYLQRLRDEAHRWAIGAHRQKRAAEAARSPLDEIEGIGPTRKKALLHHFGSARGVSRAKVADLMEVDGVNEALAIRIYGHFNSG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP73_YEAST
Sequence: MSRAVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGESGGFPGSMPNSGATGGGEDTGPTVEEVD
What are the official names of this protein?
Heat shock protein SSA3.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTFE_AMYOR
Sequence: MRVLLSTCGSRGDVEPLVALAVRLRARGAEVRMCAPPDCADRLAEVGVPHLPLGRSARPAAAGEAKPLTAEDMLRFTTETIAMQFDRIPAAAEGCDAVVTTGLLAAALGVRSVAEKLGIPYFYAFHCPSYVPSPYYAPPPPLGEPPAPEGTDIRALWERNNQSAFRRYGAPLKSQRAAIGLPPVEDIFEHGYTDHPWMAADQVLAPLQPTDLDAVQTGAWILPDERPLSPEMEAFLDAGTPPVYLGFGSLRAPADAAKVAIEAIRAHGRRVILSRGWADLVLPDDRDDCFATGEVNQQVLFRRVAAVIHHGGAGTTHVATRAGAPQILVPQIADQPYYAGRVAELGIGVAHDGPTPTFESLSAALTTALAPETRVRAEAVAGTVLTDGAAAAADLLFAAVGEEKPAVPA
What is the function of this protein?
D-glucosyltransferase that acts on the aglycone core, transferring D-glucose to the phenolic hydroxyl of OH-Phegly(4) to form a devancoaminyl-vancomycin (DVV) intermediate in the biosynthesis of glycopeptide antibiotic vancomycin.  Also able to glycosylate A47934, an antibiotic with a teicoplanin-like heptapeptide, but lacking sugar residues.
What are the official names of this protein?
Glycosyltransferase GtfE.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
Protein: HIS2_SULAC
Sequence: MSDNVIDKLYSIILDRMKTMKEGSYTVELIKRGKHYVAQKVGEESTEAIIASLVESQQRFVEEVSDLIYHLLVLMALENVTPQDVYKELERRMKK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C2_LEMMI
Sequence: MIWHVQNEVFILDSTRIFMKAFHLLLFNGSFILPECILIFGLILLLMIDSTSDQKDRPWFYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFILTATLGGMFLCGANDLITIFVALECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGLSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYIAMNLGTFARIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRKSPLRSNNSIELSMTVCVIASTIPGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ITRY_CASLE
Sequence: SVELDSDGEPIRNGGGLYYILPVVQGKGGGLEFAKTGSQS
What is the function of this protein?
Inhibits trypsin but not chymotrypsin, papain or porcine pancreatic alpha-amylase.  Has insecticidal activity against A. aegypti.  Functions by inhibiting the A. aegypti midgut proteases to reduce the survival of larva and adults.
What are the official names of this protein?
Trypsin inhibitor, ClTI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: RL14_STAAC
Sequence: MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MINC_XANOM
Sequence: MASVNVDFEQAGELKIGQVGIANLRVRTLDVPRLVQEMRERVTRAPKLFGRAAVILDFGGLSQVPDLATAKALLDGLHEAGVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYESAAVSPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENCDLTVLSTVGAGAEVIADGSIHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGNYKVLDDVPMDLRGKAVQVWLEQDQIKIAALD
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: CLPX_ARTS2
Sequence: MARIGESTDLLKCSFCGKSQKQVRKLIAGPGVYICDECIELCNEIIEEELAEVADLGSFELPKPREIYDFLQEYVIGQEPAKRSLAVAVYNHYKRIQAGHAPKSGSLAEGVHHDDVEIAKSNILLIGPTGCGKTYLAQTLARRLNVPFAVADATALTEAGYVGEDVENILLKLIQAADYDVKKAEQGIIYIDEIDKISRKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNVLFIVAGAFAGLEDIIGSRSGRKGIGFGAPLNEVKNNSDSYGEVMPEDLLKFGLIPEFIGRLPVITTVSNLDRPALIQILSTPKNALVKQYQKMFQLDGVELLFDDEALDVIADQALERGTGARGLRAIMEEVLLPVMFDLPSRDDIASVVITADVVAKKAPPTMIAHDVVAKRRNKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PBPA_CLOAB
Sequence: MSDNTKTNSRNKSVKRTKKVKKKKKFGFFKKLFTILFCLFILLSVAASGVIFAIVKTSPNLDINGTILNLDQPSQLYDDNNNPMDTVVTNQRRYVVSIKDMPKNLSNAFVSIEDERFYKHSGIDTKRILGAFYNDIKSKIHKQNSIQGASTITQQLIKNRMFLNDSLENRISFKRKIQEAYLSIKLEQSLSKSQILEAYMNTIFLGVQANGVEAASRQYFNKSAKDLNLIECAFIAGLAQSPSAYYPFSQNVAKNPNIYLDRTKLVLYKMRQNNYIDFSTYQNAINDLNNNKLAFSQQKISNKYTYEWFSIPVVNQVKQDLKSQYHYTDEEIDSLLRDGGLKIYTTMNTSMESNVQNILDNNSTLKSYSYADKNGIIQPEAAATLFDYHTGEIKAIVGGRGQQPPSSYNRADSSNYLRSVGSSIKPLTVYAPAIDTKLATEDTIVNDSPLSSDVAEKYGSNGVPYNPHNDDGGYSGPVNLKTALTKSINLVAIKLEDKLGLSTGAAYAQKFGLTLNNDDKSSIAALSLGEIRGSNTTTMAAAYGVFGNNGLYSEPRLYRKVVDKTGKVLLENNYSTRKVISPQSAYIMYDLLKGPVSAGGTGSYARFGDMPVAGKTGTASDSKNLWFCGLTPYYSAAVWVGNDQPTKLSLGSNDVAEIWGEIMKMANVNLTVKDIDAPGGVTKIGDSYYIDGTSPSNLSGDDSSSSTASKPQTPTTNTQNNTNNNVANPNSNNTTNSNTSNSTETPAQNTQQPTPTPTPSTNNTPGNTNTNTNTNNNTNTNTNTNNNNTNNSSSGNNNPPNNNTTNTNK
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
What are the official names of this protein?
Penicillin-binding protein 1A, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: SYP_XANP2
Sequence: MRLSRYFLPILREVPKEAEIVSHRLMLRAGMIRQESAGIYAWLPFGLRVLNKVCNIIREEQNRSGAIEMLMPTIQSADLWRESGRYDDYGKEMLRIKDRHEREMLFGPTNEEMITEIVRAYVKSYKALPLNLYHIQWKFRDEVRPRFGVYRSREFLMKDAYSFDLDAAGARHSYNKMFVAYLRTFARMGLKAIPMVADTGPIGGNLSHEFIILASTGESEVFCHGDYLEMAPPSADVNFDDAAGLQSVFDRWTELYAATSEKHDEAAFAAIPEASRMAARGIEVGHIFYFGTKYSEPFGAKVLGADGAEHTIHMGSYGIGPSRLVAAMIEASHDDNGIIWPDAVAPFQVGILNLKAGDSTTGAACEKLYAELTAAGYDVLYDDTEERAGAKFATADLIGLPWQILVGPKGLADGKVELKRRVDGSRELIAPGDILERLKA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCND1_GORGO
Sequence: MAATEPILAATGSPAAVPPEKLEGAGSSSAPERNCVGSSLPEASPPAPEPSSPNAAVPEAIPTPRAAASAALELPLGPAPVSVAPQAEAEARSTPGPAGSRLGPETFRQRFRQFRYQDAAGPREAFRQLRELSRQWLRPDIRTKEQIVEMLVQEQLLAILPEAARARRIRRRTDVRITG
What is the function of this protein?
May regulate transcriptional activity.
What are the official names of this protein?
SCAN domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: BIOD_BACC0
Sequence: MSGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKALQSGHVASNPEGDAARLKVLSGVPTKEDEICPYSIEEPLAPRLAMKRAGRAVTLKDIIHHYNERLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKAHGLTVAGVILSGCKECEMERVQENKVMIEELSGVPVLGLLPFFEGEFTKEEVLESAKEYIMISKLEEFIRNESTVAHTSSN
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_BORPA
Sequence: MRFDKLTTKFQQALADAQSLAARNDHPYIEPVHVLAALLGDPDSGAASLLARAGVAVNRVQPAIDSALKGLPQVQGEDNVQVGRELQSVLVRTDKEAARRGDTYIASELFLLALADDKGDAGRILREAGLQKKALEAAIDAVRGGENVSGAEGESNREALSKYTLDLTERARQGKLDPVIGRDDEIRRTIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPETLRGKRVLSLDLAALLAGAKFRGEFEERLKAVLKELAQDDGQNIVFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYRKYIEKDAALERRFQKVLVGEPDVESTIAILRGLQERYELHHGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAGARIRMEIDSKPEVMDRLDRRIIQLKIEREAVKKETDDASMRRLAVIEEELEKLQREYNDYEEIWKAEKAAVQGTQAIKEEIDRVRAEMAELQRKGQFDKLAELQYGKLPELEARLKAADSAEREAGESDSGKPRLLRTQVGAEEIAEVVSRATGIPVAKMMQGERDKLLRMEDFLHKRVVGQDEAVRLVSDAIRRSRAGLADPSRPYGSFLFLGPTGVGKTELTRALADFLFDSEEHMIRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIVMTSNLGSQHIQSMAGKPYEVIKEVVWDELKHTFRPEFLNRIDEVVVFHGLEAQHIESIARIQLKRLGERLEKQEMRLDVSDAALAEIARSGFDPVFGARPLKRAVQQQIENPVAKLILEGVFGPRDVVPVDWQDGKFVFTRTLQ
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWC26_YEAST
Sequence: MALHQYLSETYGPTKPKNKTKKKKKESKSDANSDKTSLIVKERLSTLQQEQEKSGVASFSKFDKQKSKNIWKNLETNELSHAITHPSASSITGNESKNDLKEIRAQEPLVTVADKSKTRKTIYRDAQGHKIQEDSKIDDSSFSRSKYEDEKAAEREQYLKNLNMGDVQKLGINVDAHDKKKNQTASSLTIEDPAITFTHDKERTVKTSLLGRKLYDKPAPENRFAIMPGSRWDGVHRSNGFEEKWFAKQNEINEKKVQSYTLQEDY
What is the function of this protein?
Required for efficient splicing and pre-mRNA nuclear retention.  May also be involved in positioning the proximal bud pole signal.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC26, Bud site selection protein 13, Complexed with CEF1 protein 26, Synthetic lethal with CLF1 protein 7.
What is the protein family that this protein belongs to?
Belongs to the CWC26 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSBW_STAA3
Sequence: MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYKENNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: NU6M_MYXGL
Sequence: MKIMMILEMLFLIGMVILVVDISPYFGALGLIVVSLVGCLIILAKGNSFLSLSLLLIYLGGMMVVFSYCTALVLDLYPTVIVKEVLMKMALGVLVVVFLGYGGYLKADNGVLSMLGEGGVDNSFLGAGVLYGESWLLIVFGCLGLFLALLVILEITKSAERGAYRVI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CA053_HUMAN
Sequence: MAARQIWARTGAALCRQPSAAPPPAPLWVRAGFRQQLSLTLCPANEGNCGGSAPSTPGRPERAARPSVSEELTAAERQIAELHAAACAAGQLNYVDPATGYVVLTQIAHLQRGECCGSACRHCPYGQVNVKDPSKKKQFNSYFYV
What are the official names of this protein?
Uncharacterized protein C1orf53.
Protein: HXUB2_HAEIF
Sequence: MKMRPRYSVIASAVSLGFVLSKSVMALGQPDTGSLNRELEQRQIQSEAKPSGELFNQTANSPYTAQYKQGLKFPLTQVQILDRNNQEVVTDELAHILKNYVGKEVSLSDLSNLANEISEFYRHNNYLVAKAILPPQEIEQGTVKILLLKGNVGEIRLQNHSALSNKFVSRLSNTTVNTSEFILKDELEKFALTINDVPGVNAGLQLSAGKKVGEANLLIKINDAKRFSSYVSVDNQGNKYTGRYRLAAGTKVSNLNGWGDELKLDLMSSNQANLKNARIDYSSLIDGYSTRFGVTANYLDYKLGGNFKSLQSQGHSHTLGAYLLHPTIRTPNFRLSTKVSFNHQNLTDKQQAVYVKQKRKINSLTAGIDGSWNLIKDGTTYFSLSTLFGNLANQTSEKKHNAVENFQPKSHFTVYNYRLSHEQILPKSFAFNIGINGQFADKTLESSQKMLLGGLSGVRGHQAGAASVDEGHLIQTEFKHYLPVFSQSVLVSSLFYDYGLGKYYKNSQFLEQGVKNSVKLQSVGAGLSLSDAGSYAINVSVAKPLDNNINNADKHQFWLSMIKTF
What is the function of this protein?
Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of HuxA.
What are the official names of this protein?
Heme/hemopexin transporter protein HuxB.
What is the protein family that this protein belongs to?
Belongs to the TPS (TC 1.B.20) family.
What are the subcellular locations of this protein?
Cell outer membrane.