PharMolix/UniProtQA huggingface dataset:
Protein: VSPI_GLOHA
Sequence: IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLPSSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAGNTDASCPP
What is the function of this protein?
Thrombin-like enzyme that shows fibrinogenolytic activity against both the Aalpha (FGA) and Bbeta (FGB) chains of bovine fibrinogen.  This enzyme has poor esterolytic activity upon BAEE substrate.  It induces mouse thoracic aortic ring contraction with EC(50)=147 nmol/L.  It shows vasoconstrictor effects that are independent of the enzymatic activity, but related to the release of calcium ions form the calcium store, potentially through the activation of ryanodine receptors.
What are the official names of this protein?
Thrombin-like enzyme AhV_TL-I, SVTLE AhV_TL-I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21A_RHIME
Sequence: MQVLVRDNNIDQALRVLKKKMQREGVFREMKMRSAYEKPSEKRVREKAEAVRRTRKLARKKLQREGLLPSPKKVARAR
What are the official names of this protein?
30S ribosomal protein S21 A.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: MAO1_SALPB
Sequence: METTTKKARSLYIPYAGPVLLEFPLLNKGSAFSVEERRNFNLSGLLPEVVESIEEQAERAWLQYQGFKTEIDKHIYLRNIQDTNETLFYRLVQNHLEEMMPVIYTPTVGAACERFSEIYRRARGVFISYPNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRHPRITDDEYYAFVDEFIQAVKQRWPDILLQFEDFAQKNAMPLLTRYRDEICSFNDDIQGTAAVTVGTLIAASRAAGSQLSEQKIVFLGAGSAGCGIAEQIIAQTQREGLSEDAARQNVFMVDRFGLLTDRMPNLLPFQAKLVQKCDNLQHWDTENDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFSPVIWKDKVYPIAQCNNAYIFPGIGLGVIASGASRITDEMLMSASETLAKHSPLVNNGEGLVLPALKDIQVVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWKPEYRDYRRTSI
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: SOXB_RHOCB
Sequence: MRRYSIFAVAREALRYHSGWEKAWASPEPKKRYDVIVVGAGGHGLATAYYLGKVHGIKNVAIIEKGWLGGGNTGRNTTIIRSNYLQDPSAAIYEKARSLYEGLSQDLNYNVMFSPRGLLMLAQSEHEMRGYKRTVYANNLQNVETRWIEPKEVKKLVPILNIAGPRYPVLGALLQEKGGTARHDAVAWGYARACSDMGMDLLQNTEVTGVRTEGGRVVGVDTSRGSIDCGKLAIVVAGHSSVLAGMAGFRLPIESMALQAWVSEPIKPTIDVVVMANLVHGYMSQSDKGELVIGGGTDGFNNYSQRGSWHHVEETTRALIETFPVISRLKMLRQWGGIVDMTGDRSPILSKTPVDGIFVNCGWGTGGFKAIPGSGFAMAELVAKGYSPLAAEFGLHRFKEGQFIDESVAAGVAH
What is the function of this protein?
Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10-methylenetetrahydrofolate.
What are the official names of this protein?
Sarcosine oxidase subunit beta, Sarcosine oxidase subunit B.
What is the protein family that this protein belongs to?
Belongs to the SoxB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED7_NEUCR
Sequence: MADTEDDNSALASFFPDPPLFWKAFTPSNLQAYAEIKQQYASQHGIPVEDVVRVPDLPADSDLIYLQPPAEPKDGTWRLYGEPQSLEESLQPLESAGIERLGPPLPGSTTTSTSNTQTTTTDSQSTTQPTTDDTQPTSAFPSQQPTSQLPLPPSSTSAPGGASSGASSTQTHDTLHLHLKRLSKSLLLNFLELLGIMSLDPAAGSQKAADLRTLFLNFHHVLNEYRPHQAREQLIQLMQERLDQTRAETAANRAVAEKARRVLEGLGSVEIPAVDDVNIAGTGTGGGDGEAGYGSAAVPVPVPVGARTGTTVGDRRVGVDGEGAEEEEKMYWEREGMGWGVLDAEFA
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7, Mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSTA_ECOLI
Sequence: MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKTTPPAVLLARLRLHLRQNEQATLTKGLQETSLTPYKALHFGTLTIDPINRVVTLANTEISLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHAWE
What is the function of this protein?
Member of the two-component regulatory system RstB/RstA.
What are the official names of this protein?
Transcriptional regulatory protein RstA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_METTH
Sequence: MLQVILNIRLDHKTSDVKTMESSHERMEAIVAELESSGTVMEKVPIRTCNRIEYYLSVQEIPPGFEFDGFTVEGDEDALRHILRLASGLESMIIGEDQILGQIKAARVQALREGTCGPVLDMVFTKAVHVGQTVRRKTQINRGSVSIGSAAVDLAESIHGDLKCRKVLAIGAGKMGTLVARALAEKHLSAIMVANRTYERAYQLACELGGDAIHFDRLNRALRDADVVISATGSPHYILTRERVRDAIPPERRSAVVMVDIANPRDIEESVRELGIRLFTIDDLRGVAEENRRRREAEAREAERIVEGELKLLLRSLKHMEVEPLLAEVRGNMESLRRREAERALNKIMNSSDPEGVIEALSRSIVDKIFHDIAISIRQAAERGDEEFLSMCAKLFNCKDLK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: UBIB_ACISJ
Sequence: MSRFARGITIVWVVLRYGLDELVLSTFRQPWLRAVTRVITFGRKLDAPRGQRLREALESLGPIFVKFGQVLSTRRDLMPPDIADELALLQDRVPPFDPDVAIATIERAFRRPIGEVFVSFDRQPVASASIAQVHFAVIRDRQGHAREVAVKVLRPGMLPVIDKDLALMRMMAGWVESLSADGKRLKPREVVAEFDNYLHDELDLVREAANAAQLRRNMQGLDLVLIPEVFWDFCHAEVLVMERMKGVPINQVDRLRSAGVDIPKLARDGVTIFFTQVFRDGFFHADMHPGNIQVSLAPETFGRYISLDFGIVGTLTEFDKEYLAQNFTAFFRRDYKRVAELHIESGWVPAHTRVNELEAAIRTVCEPYFDRPLKEISLGMVLLRLFQTSRRFQVEIQPQLVLLQKTLLNIEGLGRQLDPDLDLWSTAKPFLEKWMLDQLGPQRLWRELRAEAPHYAKILPDLPRLLHDFLRQRPNDNRVDLQELLATQKRTNRLLQSLIYGGLGFVLGLLVMQLFVRVRIF
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MINE_PELTS
Sequence: MLEFLTRLFSKDGGSKNVAKERLRLVLVHDRTSISPQLLETLKAELIKVISNYMEIDEAALEVSLDSSGNTVALVASIPVKGMKRVAGTA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: CRTZ_PANAN
Sequence: MLWIWNALIVFVTVIGMEVIAALAHKYIMHGWGWGWHLSHHEPRKGAFEVNDLYAVVFAALSILLIYLGSTGMWPLQWIGAGMTAYGLLYFMVHDGLVHQRWPFRYIPRKGYLKRLYMAHRMHHAVRGKEGCVSFGFLYAPPLSKLQATLRERHGARAGAARDAQGGEDEPASGK
What is the function of this protein?
Catalyzes the hydroxylation reaction from beta-carotene to zeaxanthin.
What are the official names of this protein?
Beta-carotene hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
Protein: GSA_PAEAT
Sequence: MTSNTPVSDQLFDRARSLMPGGVNSPVRAFGSVGGTPKFMVSAKGAYLTDADGKEYVDLVCSWGPALLGHAHPAVLDAVHAAVDRGLSFGASTPDEANLAAIVKDRVSAVERLRMVSTGTEATMTAVRLARGFTGRNLIIKFAGCYHGHLDGLLAAAGSGVATLALPGSAGVTEATAAETLVLPYNDLAAVEAAFAAHGKNIAAVITEAAPANMGVVTPGEGFNAGLSRITKEHGALLILDEVLTGFRTGYAGYWGLTGRQEGWAPDLLTFGKVIGGGMPTAALGGRADVMDYLAPVGPVYQAGTLSGNPVAMAAGVATLTNATPEVYAYVDARSLELSAALSSALDAAGVDHSIQRAGNLFSVAFGTSAHGVHNYDDAQRQESFRYAPFFHSMLDSGVYLPPSVFEAWFLSAAHDDAAMNRIVDALPAAAKAAAGASA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_THEYD
Sequence: MGNFKIYTSFKPKGDQPKAIKQLVEGIKKGYKHQVLLGVTGSGKTFTIANVIEKVNKPTLVIAHNKTLAAQLYGELKELFPYNAVEYYVSYYDYYQPEAYIPETDTYIEKDALINDDIDRMRHSATLSVLTRQDVIVVASVSCIYGIGSPDDYMSMHVTLEEGMKTERDAMLKKLVEILYIRAEEEFRRGAFRVRGDVVDIFASHCLDKAYRVEFFDDEIDAIYEIDPLTGSRQKRLQRIFIPPNSHWVTPEPRLKKALETIEEELQERIKYFKERGEELFAERIEKRTRFDMELLSQFGHCHGIENYSRHLSGRLPGEPPFTLIDYIYAGPSKGDFLTVIDESHVTVPQIGGMYEGDRSRKQTLVEYGFRLPSALDNRPLTFKEFEHRMNYVIYVSATPGDYEIEKSGGRIVEQIIRPTGLVDPKIEVRPATNQVEDLLEEIHKRVSRGERVLVTTITKKMAEDLTDYYTTVGIKAKYLHSDIDTLERVEILKDLRLGKFDVLIGVNLLREGLDLPEVSLVAIFDADKEGFLRSERSLIQTAGRASRNINGTVIFYADTVTDSMKKAIEETERRREIQMKYNKKNGISPETVKSKIKDILSSIYEKDYVTVDVVKEEAEEYELNEETIKKLEQEMKHAAENLEFEKAAEIRDKIFKIKEKMLKLGMKLTV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHN2_ARATH
Sequence: MVHSRKFRGVRQRQWGSWVSEIRHPLLKRRVWLGTFETAEAAARAYDQAALLMNGQNAKTNFPVVKSEEGSDHVKDVNSPLMSPKSLSELLNAKLRKSCKDLTPSLTCLRLDTDSSHIGVWQKRAGSKTSPTWVMRLELGNVVNESAVDLGLTTMNKQNVEKEEEEEEAIISDEDQLAMEMIEELLNWS
What is the function of this protein?
Promotes cuticle formation by inducing the expression of enzymes involved in wax biosynthesis.  Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor SHINE 2.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL20_SALDC
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: Y038_ATV
Sequence: MFKTVQKEPIPLTENFSKFSPLEAKSCWWGFIILFLAF
What are the official names of this protein?
Uncharacterized protein ORF38.
Protein: MURC_TRIL1
Sequence: MYGNIEKIHFVGIGGIGMSGIAEVLLNLGYQVSGSDLRESDTTERLRSLGGEICIGHAAENLTNVDVVVTSTAVQSDNPEVIEAKHRMVPVIPRAEMLAELMRMKYGIAIAGTHGKTTTTSMVATVLTHAGIDPTIVIGGKLNTLGSNAKLGQGKFLVAEADESDGSFLTLSPTIAVVTNIDADHLDYYTGGLEQIKDTFVSFINKVPFYGLAVLCQEDRNINEIIPRIKKRFMTYGLSSQADLRATHVKLDGFQTTFTAHYKGYRLGEISFNMPGAHNVLNALACTAVALELDVPFDKIQEGFAQFGGVGRRFTVKGEKNGIMVVDDYGHHPAEIRATLGAARNGWPERRLVVAFQPHRYSRTKELFNEFVTCFYDADVLVLTDIYAASEQPIPGVSAERLAEETRRHGQRDVTYIADRNDLPDYLAGIVKEGDIVITLGAGNIWQAGEALVKRL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGB_DANRE
Sequence: MEKLSEKDKGLIRDSWESLGKNKVPHGIVLFTRLFELDPALLTLFSYSTNCGDAPECLSSPEFLEHVTKVMLVIDAAVSHLDDLHTLEDFLLNLGRKHQAVGVNTQSFALVGESLLYMLQSSLGPAYTTSLRQAWLTMYSIVVSAMTRGWAKNGEHKSN
What is the function of this protein?
Involved in oxygen transport in the brain (By similarity).  Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom.  Capable of penetrating cell membranes.
What are the official names of this protein?
Neuroglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Perikaryon. Cytoplasm. Note=Located in the soma (perikaryon) of most nerve cells in brain. Has ability to penetrate cell membranes and translocate into cells.
Protein: PVK1_NEORO
Sequence: GASGLIPVMRN
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, NeoRh-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRIL_HALMA
Sequence: MEPLHARYPFLARSREAVEAAAVDLGEIVATDETVTARALERVESAITDGTVGEPHRRTRVELLSYPVARVLVSLVDVHICTRKYAQAEAEAAYDRFTEEFATTTELKSTQRETLDRTELLGEFDLASAVSDAGDGYRVEVGAYLDLAADQRGDSWRLVNRPLTDGEVRVTAEELNVLLKQAIRHRVTDGLPFTVPDAIADELTAEVEQLEEVLSELELTREIDTVVPELFPPCMKSLLDQVQKGEHLEHHSRFAIATFLVGIGMTTDEIVDLFQVNPGFGEEATRYQVDHIRGDTSPTEYSTPACSTMQSYGDCVNMDDLCEAISHPMGYYEQKLDDTDEEELVDWREDEGEEEADA
What is the function of this protein?
Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase large subunit PriL.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase large subunit family.
Protein: MDCG_XANCP
Sequence: MAGRHALVWLRADAPSQALTPGAQPRLQAWFAAGFPAVVARRDGAEQPGQVRLGVPLPPAQGKQRIALCAQVSDIARSVPALALPEVISHAPPQWQAALHALQAQATAIGMQPRVFGSFAFQAVTGLPYVHAASDVDLLWTLDTPTQAHAVVTLLQQWEHVTARRADGELLLPDGNAVNWREYAGDAQQVLVKRNDGCRLLPRTALFPERCAA
What is the function of this protein?
Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].
What are the official names of this protein?
Phosphoribosyl-dephospho-CoA transferase, Malonate decarboxylase holo-[acyl-carrier-protein] synthase, Holo-ACP synthase.
What is the protein family that this protein belongs to?
Belongs to the MdcG family.
Protein: WZZB_SALTY
Sequence: MTVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVIIAILLAVGYLMIAKEKWTSTAIITQPDAAQVATYTNALNVLYGGNAPKISEVQANFISRFSSAFSALSEVLDNQKEREKLTIEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVAKELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMIQNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVLAVLLGGMIGAGIVLGRNALRSYKPKAL
What is the function of this protein?
Confers a modal distribution of chain length on the O-antigen component of lipopolysaccharide (LPS).  Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 20.
What are the official names of this protein?
Chain length determinant protein, Polysaccharide antigen chain regulator.
What is the protein family that this protein belongs to?
Belongs to the WzzB/Cld/Rol family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOB_STRPQ
Sequence: MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVGRYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKFVYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIVWLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQHNGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIADGPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: FAPR_STAHJ
Sequence: MKLKKAERRQAIQKAIELNPFITDSELCEQFEVSIQTIRLDRTNLSIPELRKRIKLVAEQNYEQIRALEANEVVGDLIQVEPNISAQSLIEITEESVFTKTQIARGHVLFAQANSLCVALIHKSTVLTQESNVAFIEKVKLNDTVRAEAHVVNKTSHHYVIEVNSYVRDTIVFKGTFKMFYISEDE
What is the function of this protein?
Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
What are the official names of this protein?
Transcription factor FapR, Fatty acid and phospholipid biosynthesis regulator.
What is the protein family that this protein belongs to?
Belongs to the FapR family.
Protein: COPA_STAAR
Sequence: MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDRHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNRDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGCPVVTDYHGDDQTLQLLATAEKDSEHPLAEAIVNYAKEKQLTLTETTTFKAVPGHGIEATIDHHHILVGNRKLMADNDISLPKHISDDLTHYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQITKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
What is the function of this protein?
Involved in copper export.
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1225_HAEIN
Sequence: MSDSVLVYSTDVGRIKEEKASVVRPKGDGVVRIQKQTSGRKGAGVSVITGLDLSDEELKKLAAELKKRCGCGGAVKNGIIEIQGEKRDLLKQLLEQKGFKVKLSGG
What are the official names of this protein?
Uncharacterized protein HI_1225.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: TBB_GIBZE
Sequence: MREIVHLQTGQCGNQIGAAFWQTISGEHGLDSNGVYNGTSELQLERMSVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICMRTLKLSNPSYGDLNYLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGRVAMKEVEDQMRNVQSKNSSYFVEWIPNNIQTALCAIPPRGLTMSSTFIGNSTSIQELFKRVGEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAGIDEEEEEYEEELPEGEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MYO7A_PIG
Sequence: MVILQQGDYVWMDLRSGQEFDVPIGAVVKLCDSGQIQVVDDEGNEHWISPQNATHIKPMHPTSVTGMMEDMIQHLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGARIEQYLLEKSRVCRQAPDERNYHVFYCMLEGMSEEQKKKLGLGQATDYNYLAMGNCITCEGREDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYKDRTFENLDACEVLFSTALATAASLLEVNPPDLMNCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQEVKNPRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHRLNSNYIPPKYNHETQFGINHFAGVVYYESQG
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments.  In the retina, plays an important role in the renewal of the outer photoreceptor disks.  Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors.  In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles.  Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells.  Required for normal hearing.  Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity).
What are the official names of this protein?
Unconventional myosin-VIIa.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Synapse. Note=In the photoreceptor cells, mainly localized in the inner and base of outer segments as well as in the synaptic ending region (By similarity). In retinal pigment epithelial cells colocalizes with a subset of melanosomes, displays predominant localization to stress fiber-like structures and some localization to cytoplasmic puncta (By similarity). Detected at the tip of cochlear hair cell stereocilia (By similarity). The complex formed by MYO7A, USH1C and USH1G colocalizes with F-actin (By similarity).