PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_GEOTN
Sequence: MGEIDMNEDVYVLGIETSCDETAAAVVKNGKEIVSNVVASQMESHRRFGGVVPEIASRHHVEQITLVIEEAMQRAGVSFSNLDAVAVTAGPGLVGALLVGVNAAKALAFAHGLPLVGVHHIAGHIYANQLVAEMKFPLLALVVSGGHTELIYMEEHGKFTVIGETRDDAAGEAYDKVARALGLPYPGGPHIDRLAHEGEPVIDLPRAWLEEGSYDFSFSGLKSAVLNTLHNAKQRGEEIDPKHMAASFQESVVDVLVTKTVQAAKQYRVRQVLLAGGVAANRGLRSALQDKMKELPGVELVIPPLSLCTDNAAMIAAAGTVLYWQGKRSDLALNANPGLPLV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_MYCS2
Sequence: MSRASLEKNPHDVASMFDAVAKRYDLTNTVLSLGQDRFWRRETKSALRIGPADKVLDLAAGTAVSTVELAKSGAWCVAADFSVGMLAAGASRQVPKVAGDATRLPFADEVFDAVTISFGLRNVVDHKAGLREMARVTKPGGRLVVCEFSTPTNRLFSTVYKEYLMKALPAMATAVSSNPEAYVYLAESIRAWPTQAELARQIGEAGWSDVRWRNLTGGIVALHAATKPA
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RIBA_ALIF1
Sequence: MANVRARIELMVGQKSNIPAEMLSFEGLETDKEHVAVVFNQADKHQSTPLVRMHSECLTGDVFHSSRCDCGEQLEETINRMSESGGIILYLRQEGRGIGLYNKLDAYELQSQGMNTYEANNHLGFGDDLRDFKEAAQMLEALNISKIKLVTNNPKKIKDIQNYGIEIDEVVNTHAHVKQGNEHYLHSKAAHGHKLNFDK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: MOAC_CAMJ8
Sequence: MKLSHLDEKNHPKMVDVSDKNITSRIATASGMIYMSQEAFDVIKNNTAKKGPVLQTAIIAAIMGAKKTSEIIPMCHPLMLSKVETDIMEFVKECAFKLIVTVKCEGKTGVEMEALSGVSIGLLTIYDMIKAIDKSMRITDILLESKEGGKSGKFVRS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PHS_BOVIN
Sequence: MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDVNLASFIEQVAVSMT
What is the function of this protein?
Involved in tetrahydrobiopterin biosynthesis.  Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2.  Coactivator for HNF1A-dependent transcription.  Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity (By similarity).  Also acts as a coactivator for HNF1B-dependent transcription (By similarity).
What are the official names of this protein?
Pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Dimerization cofactor of hepatocyte nuclear factor 1-alpha, DCoH, Dimerization cofactor of HNF1, Phenylalanine hydroxylase-stimulating protein, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Recruited to the nucleus through the interaction with HNF1B.
Protein: YKFG_ECOLI
Sequence: MKQLSFLPGEMTPQDRRLIQRALRALDRHLHEPGVAFTSTHAVREWLRLHMAALEREEFRVLYLDNQNQLIAHETLFTGTINRTEVHPREVVKRALHFNAAAVILAHNHPSGETTPSQADKTLTQRLVQVLQLVDIRVPDHLIVGGRQIYSFAEHGLL
What are the official names of this protein?
UPF0758 protein YkfG.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: ARNF_PSEPF
Sequence: MNRRRGILFALASVLLVSVAQLSMRWSMTRLPRPDQWLSVPSVDSVALAVVLAAIFAYALSMLCWLAALRDLPLGRAYSLLSISYALVYLLAASLPLFNESFSFSKSLGVALVMLGVITINTRPARAPELRSSP
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CANB_ASHGO
Sequence: MGSAPSKILEDLLDDTNFDREEIERLRKRFMKLDRDSSGSIDKNEFMSIPGVSSNPLAGRIMEVFDADNSGDVDFQEFISGLSVFSGRSDKEEKLRFAFKIYDIDKDGYISNGELFIVLKIMVGNNLEDEQLQQVVDRTIMENDVDGDGKLSFEEFKSAVETTEVANSLTLQCDI
What is the function of this protein?
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase.  Confers calcium sensitivity (By similarity).
What are the official names of this protein?
Calcineurin subunit B, Calcineurin regulatory subunit, Protein phosphatase 2B regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
Protein: YCF29_GUITH
Sequence: MDKELKKEKIKLILIEPEEHLGYLLSEFFYQQNFVTYISESFIHLTDIINLHNPDIIIIDDSQNLETYKLSNIYLPIILLTTRGLKNDRMKIHKLGFDAYMLKPFDPDELIAIISNLIYKKRNIKELQFIKHRISNLNLKLKYRETSFSYINLTVKEKEVFKFIQDGLTNKQISNVMGITQRSVEKYVTKIFEKLKIQNRIQILSYFN
What are the official names of this protein?
Probable transcriptional regulator ycf29.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: S100G_HUMAN
Sequence: MSTKKSPEELKRIFEKYAAKEGDPDQLSKDELKLLIQAEFPSLLKGPNTLDDLFQELDKNGDGEVSFEEFQVLVKKISQ
What are the official names of this protein?
Protein S100-G, Calbindin-D9k, S100 calcium-binding protein G, Vitamin D-dependent calcium-binding protein, intestinal, CABP.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
Protein: PYRB_AZOVD
Sequence: MTPNDAKRPLQLNDQGRLRHFLSLDGLSRELLTEILDTADSFLEVGTRAVKKVPLLRGRTVCNVFFENSTRTRTTFEMAAQRLSADVITLNVSTSSTSKGETLFDTLRNLEAMAADMFVIRHADSGAAHFIAEHVCPDVAVINGGDGRHAHPTQGMLDMLTIRRHKGGFENLSVAIVGDILHSRVARSDMLALRALGCPDIRVIGPKTLLPMGLEQYGVRVFHDLDEGLRDVDVVIMLRLQRERMQGGLLPSQGEFYRLYGLSTARLARARPDAIVMHPGPINRGVEIESAVADGAQSVILNQVTYGIAVRMAVLSMAMSGQTAQRQLNSESEEQI
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RNPA_PROMA
Sequence: MVLPKGMRLKGYKSFDYIHKSAKRYKSDSMMLRVTKANERLIKSTIKNSKSNSCRCAISISNKVSKKAVIRNRLRRLLHNHLKKRLFQKDAFSNNWLLLSLSPKCLDKNTENLLEECDKLLIEAGFC
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CPRF3_PETCR
Sequence: MSDGEEGTPMKHPKPASSVEEAPITTTPFPDLLSSMQAYYGGAAPAAFYASTVGSPSPHPYMWRNQHRFILPYGIPMQYPALFLPGGIFTHPIVPTDPNLAPTSGEVGRKISDEKGRTSAKKSIGVSGSTSFAVDKGAENQKAASSSDNDCPSLSSENGVDGSLEVRSNPLDVAAPGAIVVHDGMLPDQRVNDERELKRQRRKQSNRESARRSRLRKQAKSDELQERLDNLSKENRILRKNLQRISEACAEVTSENHSIKEELLRNYGPDGLTRLPRNLQEAAGELLIEDDTDGET
What is the function of this protein?
Binds to the G-box-like motif (5'-ACGTGGC-3') of the chalcone synthase (CHS) gene promoter.  G-box and G-box-like motifs are defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control.
What are the official names of this protein?
Light-inducible protein CPRF3, Common plant regulatory factor 3, CPRF-3.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOI_BRASB
Sequence: MNISATARSLLLSEFVSAFFLAMRYFFQPKPTLNYPFEKGPISPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIEAGPRRNDGTRRTVRYDIDMVKCIYCGLCQEACPVDAIVEGPNFEFATETREELYYDKAKLLANGDRWEREISKAIALDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1268_ARCFU
Sequence: MVSAISTVLYVLIPFLVFLFRRIDARAIMVSGIAFYPFHLFLPMIVVFITGIPLILKSKGVYITLDGIGMENPDFSDALLVIDTMLFQIMLLQPFITLIYSRGVDLKIQDVRLILGTPLRRRILSSLFAFVIAGIALPEIVLLNFSGILHVDYLFFVHLIASSVFANLLVPSDSSKTSLVVFYLWVYIS
What are the official names of this protein?
Uncharacterized protein AF_1268.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPF_PSEAE
Sequence: MPAVRIKICGITRVEDALAAAAAGADAIGLVFYAKSPRAVDIHRAREIVRALPPFVTSVGLFVNASRCELGEILDAVPLDLLQFHGDERAEDCEGHRRPYLKALRMKPGDDIVGRAAAYPGAAGILLDTYVEGVPGGTGAAFDWSLVPTDLGKPLVLAGGLTPDNVGRAVEQVKPYAVDVSGGVEASKGIKDAARVRAFVDAVRSRRRDET
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: YIDD_RHORT
Sequence: MRPLAALSQGIGLLMRGLIWLYRLFLSPLLGQNCRFDPSCSRYALEAITRHGPFWGLWLAVRRISRCHPWGGMGYDPVPDDPRPGRCGCKDAGPAVSAGSTEGNPGRRTDGTDPD
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARLY_PROMA
Sequence: MQKTWSDRFEEGLNPFIESFNASINFDFLLIEEDLDGSIAHARMLAKTGIITSEEADQLEAALQKIRLEASQGLFKPDISDEDVHMSVERRLISILGPLGKKLHTARSRNDQVGTDLRLWLRRRIDDIDIELKKLQVALFKKAEKNLLTLIPGYTHLQRAQPLSLAHHLLAYIEMLQRDRNRLADVRERVNICPLGAAALAGTSLPIDRAFTANQLGFTSIYSNSLDAVSDRDFTVEFTAAASLIMTHISRLADEIILWASEEFSFVRLTDRCSTGSSLMPQKKNPDVPELVRGKTGRVFGHLQSLLTMMKGLPLAYNKDFQEDKEAVFDTVKTVRDSLKAMTILLEEGLEFSLERLKETVEADFSNATDVADYLVSKNIPFREAYQIVGRVVRLCIQKKILLKDLTLKEWQEINTLIDHDIYEKITPEKVVAARISDGGTGFDRVREELEKWRNDLISLNQ
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_PSEPW
Sequence: MPRSLKKGPFIDLHLLKKVEVAVEKNDRKPVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVNEDMVGHKLGEFAGTRTYRGHVADKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: BMPER_HUMAN
Sequence: MLWFSGVGALAERYCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLCPQR
What is the function of this protein?
Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.
What are the official names of this protein?
BMP-binding endothelial regulator protein, Bone morphogenetic protein-binding endothelial cell precursor-derived regulator, Protein crossveinless-2, hCV2.
What are the subcellular locations of this protein?
Secreted.
Protein: AKIR1_MOUSE
Sequence: MACGATLKRPMEFEAALLSPGSPKRRRCAPLPGPTPGLRPPDAEPPPLQMQTPPASLQQPAPPGSERRLPTPEQIFQNIKQEYNRYQRWRHLEVVLSQSEACTSETQPSSSALTAPGSPGAFWMKKDQPTFTLRQVGIICERLLKDYEDKVREEYEQILSTKLAEQYESFVKFTHDQIMRRYGTRPTSYVS
What is the function of this protein?
Molecular adapter that acts as a bridge between proteins, and which is involved skeletal muscle development (PubMed:18255059, PubMed:19406121, PubMed:30746755).  Functions as signal transducer for MSTN during skeletal muscle regeneration and myogenesis (PubMed:18255059, PubMed:19406121).  May regulate chemotaxis of both macrophages and myoblasts by reorganising actin cytoskeleton, leading to more efficient lamellipodia formation via a PI3 kinase dependent pathway (PubMed:19406121).  In contrast to AKIRIN2, not involved in nuclear import of proteasomes (By similarity).
What are the official names of this protein?
Akirin-1, protein mighty.
What is the protein family that this protein belongs to?
Belongs to the akirin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRE_STAHJ
Sequence: MAKEIAKSLLDIEAVTLSPNDLYTWSSGIKSPIYCDNRVTLGYPEVRRAIRDGLSQMIIEQFGNVDIVSGTATAGIPHAAYISEKLNLPMNYVRSKSKSHGKQNQIEGAVSKGKKVVVVEDLISTGGSSITAVEALKDAGADVLGVVAIFTYGLKKADDMFNEIDVPFYTLSNYNELIEVAREEGKISENDIQTLVEWRDNL
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RS6_CLOBM
Sequence: MRKYETVFILNPALDEEGYKANVEKFKGVIENSGGTVDNVDLWGKRKLAYEVKKVSEGYYTLMNFTADTELPKELDRVFRITDTVIRHMIITQE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: HIS8_SHIF8
Sequence: MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVEFKLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLENWQLDLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIPPYPLSTPVADIAAQALSPQGIVAMSERVAQIITEREYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALRAEQV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: LTK_HUMAN
Sequence: MGCWGQLLVWFGAAGAILCSSPGSQETFLRSSPLPLASPSPRDPKVSAPPSILEPASPLNSPGTEGSWLFSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYLISAYGAAGGKGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDACPGGSPESQLVCLGESRAVEEHAAMDGSEGVPGSRRWAGGGGGGGGATYVFRVRAGELEPLLVAAGGGGRAYLRPRDRGRTQASPEKLENRSEAPGSGGRGGAAGGGGGWTSRAPSPQAGRSLQEGAEGGQGCSEAWATLGWAAAGGFGGGGGACTAGGGGGGYRGGDASETDNLWADGEDGVSFIHPSSELFLQPLAVTENHGEVEIRRHLNCSHCPLRDCQWQAELQLAECLCPEGMELAVDNVTCMDLHKPPGPLVLMVAVVATSTLSLLMVCGVLILVKQKKWQGLQEMRLPSPELELSKLRTSAIRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQDPDVLNSLLPMELGPTPEEEGTSGLGNRSLECLRPPQPQELSPEKLKSWGGSPLGPWLSSGLKPLKSRGLQPQNLWNPTYRS
What is the function of this protein?
Receptor with a tyrosine-protein kinase activity (PubMed:10445845, PubMed:20548102, PubMed:30061385).  Following activation by ALKAL1 or ALKAL2 ligands at the cell surface, transduces an extracellular signal into an intracellular response (PubMed:30061385, PubMed:34646012).  Ligand-binding to the extracellular domain induces tyrosine kinase activation, leading to activation of the mitogen-activated protein kinase (MAPK) pathway (PubMed:20548102).  Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif (By similarity).  The exact function of this protein is not known; studies with chimeric proteins demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival (PubMed:9223670, PubMed:18849880).  Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport (PubMed:20548102).
What are the official names of this protein?
Leukocyte tyrosine kinase receptor, Protein tyrosine kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RNPA_STRU0
Sequence: MKKSYRVKREKDFQAIFDGGKSTANRKFVIHFLEKEQDHYRVGISVGKRIGNAVTRNAVKRKIRHVIMEFSDHLKRDDFVVIARKGVENLDYQEVKQNLQHVLKLANLLEEGFESEKKH
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CYSH_ECOHS
Sequence: MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRP1_ARATH
Sequence: MVSHKCVEEFGYASYLVPSNARAPRSARKRRSIEKRISKEDDNMCAIDLLATVAGHLSFESGSSLMSIDKLIEDHRVKEEFPEEEKPLMPVALSPYRGSLSPCGFSSVINGKVENEVDGFSYSGGSDACQVGNFSQDVKPDIDGDAVVLDARPNVVVSLGSSSRTEVPSIGNCVSHGVRDDVNLFSRDDDENFSKYIHPRVTKHSPRTVPRIGDRRIRKILASRHWKGGSRHSDTKPWRNYYLHQQRSYPIKKRKNFDHISDSVTDDYRMRTKMHRGSRKGQGASFVASDSHVKLRIKSFRVPELFIEIPETATVGSLKRMVMEAVSTLLSDGHRVGLMVQGKKVRDDNKTLHQTGISQDNSHLDSLDFSLEPSSEMPQLLTSHPLGHACEELLPVCQATKIDNVLESDHHDSALFPSDSLGNNNVTEDSKAMISVALNELSSQSQPPSRKSRRSEQQQQQAAQRRIRRPFSVAEVEALVQAVEKLGTGRWRDVKLCAFEDADHRTYVDLKDKWKTLVHTAKISPQQRRGEPVPQELLNRVLNAHGYWTQQQMQQLQQNVNKLEQETQSQTTEGLLLL
What is the function of this protein?
Binds specifically to the plant telomeric double-stranded DNA sequences 5'-GGTTTAG-3'.  At least 4 repeats of telomeric sequences are required for binding.  Induces DNA bending.
What are the official names of this protein?
Telomere repeat-binding protein 1, AtTRP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROE_GEOSM
Sequence: MTITGKTRVTGIIGWPVAHSLSPPMHNAAFEALGLDFAYVPFPVAPERLAAGIAGLAALGVVGFSVTIPHKVAILPLLDRIAPEAELIGAVNTVAVKEGILTGYNTDGIGLLSALRSKLGFQPEGRSVLVLGAGGAARSAVASLGLAGAGRVEVANRSLDAGRGLAETMGERLPGTVFGFQPLGRVSDKGYLSGFDLVVNTTSVGMAGDGFAGLDLSALKRGASVYDMVYAPLVTPLLAQAEVVGVPSANGLGMLAAQGEAAFRIWTGAVPPEGCMEKALAARLATPGNP
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: LOVE_ASPTN
Sequence: MAADQGTFTTSVTLSPVEGSRTGGILPRRAFRRSCDRCHAQKIKCTGNKEVTARAPCQRCQQAGLRCVYSERCPKRKLRPSRAADLVSADPDPCLHMSSPPVPSQSLPLDVSESHSSNTSRQFLDPPDSYDWSWTSIGTDEAIDTDCWGLSQCDGGFSCQLEPTLPDLPSPFESTVEKAPLPPVSSDIARAASAQRELFDDLSAVSQELEAILLAVTVEWPKQEIWTRASPHSPTAFPERITQRRHNMWANWLTDLHVFSLDPIGMFFNASRRLLTVLRQQAHADCHQGTLDECLRTKNLFTAVHCYILNVRILTSISELLLSQIRRTQNSHMNPWEGSRSESPSRDDTSSTSGHSSVDTIPDFSEDLPIGELFSYVDPLTHALFSACTTLHVGVQLLRENEITLGVHSAQGIAASISMSGGPGEDIARTGATNSARCEEQPTTPAARVLFMFLSDEGASQEVKSAGSRGRTIAALRRCYEDIFSLARKHKYGMLRDLNNIPP
What is the function of this protein?
Transcription factor that regulates the expression of the he gene cluster that mediates the biosynthesis of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR).
What are the official names of this protein?
Transcriptional regulator LovE, Lovastatin biosynthesis cluster protein E.
What are the subcellular locations of this protein?
Nucleus.
Protein: CVC1_SHV21
Sequence: MDVHFDNWRFLSRPDKVIVHLLLPQTFFESHHIPFDPNLTFWSQTRFHHLDFPPTRYVKIWGKLYFSLPGLPSKACPGIAVSLVINIEENMYNPFDMTVLKILLNENIYYIKFFHMELFFPYIAPNSLQDTSIEEPFKNVDHIDAILNTTSPVTNLYKNPLGVLANLLQSRPQSSPRHHFALEDPGKVRGYEQPSLLQTDKAMPKVSYVKHKWSILNSEPTVTCVKHIFTKKSYFICSYPTMSNSQCTSVLDTISVQELAHVSPTAVLDAEKAFLFKHQHRFVNTLEHVCKSKNYAIEQHVPVLIQKDEETASSIKDHFTETCFVLESTVSEASAWVRATFARYLNKPKAFWIDYIRLWEEGVHTLGKSVPELKEDVCEEKMWHLLSLNKEFIHCIRNQGCTGVLVDSNLNAWLILPGGFVIKGHYNITPEDILFVGARYG
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.
What are the official names of this protein?
Capsid vertex component 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.