PharMolix/UniProtQA huggingface dataset:
Protein: WZYE_SALSV
Sequence: MSLMQFSGLLVVWLLSTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAACFYGVYYVTYKTRLRKRVVDVPRKPLFTMNRVETHLTWVILMGIALVSVAIFFMHNGFLLFRLHSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGLNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYHNIDFQGLAPIVRDFYVFIPTWLWPGRPSIVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFLVVFGASLLVAKLLFWLFDSAGLIHKRTTSLPQAQVEGKL
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IPYR_THELN
Sequence: MNPFHDLEPGPEVPEVVYALIEIPKGSRNKYELDKKTGLIKLDRVLYSPFHYPVDYGIIPQTWYDDDDPFDIMVIMREPTYPGVLIEARPIGLFKMIDSGDKDYKVLAVPVEDPYFNDWKDISDVPKAFLDEIAHFFQRYKELQGKEIIVEGWENAEKAKQEILRAIELYKEKFKK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF364_ASFM2
Sequence: MYFLVADHREHHVIPFLKTDFHHMHQNPIQKNQALLEIKQLFTGDYLICKSPSTILACIERKTYKDFAASLKDGRYQNRQKMLLLREQTKCQLYFFVEGPAFPNPQKKINHVAYASIITAMTHLMVRDHIFIIQTKNEAHSSQKLMQLFYAFSKEMVCVVPTSLTPTDEELCIKLWSSLSGISGVIGKIMANTCSVAHLVSGKLPSQNIDQLKTPSNRPFPKKVKRMLINISKGNKELEIKLLSGVPNIGKKLAAEILKDHALLFFLNQPVECLANIQIIQKTRTIKLGMKRAEAIHYFLNWCGSARVTVDSQNITEASRPIMQPATMQLATTQPLHKVSDEASENASHDASENASDKVSSPTGHQTISKYISKEISLNTAAK
What is the function of this protein?
Plays a role in the inhibition of type I interferon signaling pathway.  Mechanistically, specifically interacts with 2',3'-cGAMP and cleaves it via its phosphodiesterase activity.  In turn, prevents 2',3'-cGAMP interaction with host ER-resident STING1 leading to inhibition of downstream signaling pathway and type I interferon production.
What are the official names of this protein?
ERCC4 domain-containing protein EP364R, pEP364R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus EP364R family.
Protein: ST7_PAPAN
Sequence: MAEAATGFLEQLKSCIVWSWTYLWTVWFFIVLFLVYVLRVPLKINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAMSDIFCSAEFRDWNCKSIFMRVEDELEIPPAPQSQHFQN
What are the official names of this protein?
Suppressor of tumorigenicity 7 protein.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYV_HAEIG
Sequence: MTQKFEMADRFNPSAVEQALYQHWEESGYFKPSENENAPSYCIAIPPPNVTGSLHMGHAFQQTLMDTLIRFNRMEGHNTLWQAGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFINKIWDWKAYSGGTISQQMRRLGNSIDWERERFTMDDGLSNAVKEVFVRLHEEGLIYRGKRLVNWDPKLHTAISDLEVENKESKGSLWHFRYPLANDAKTADGKDYLVVATTRPETMLGDTAVAVHPEDERYQSLIGKTVILPLANREIPIIADEYVDREFGTGVVKITPAHDFNDYEVGKRHNLPMVNVLTLNANIRDEAEIIGTDGKPLAGYEATIPADYRGLERFAARKKIVADFEALGLLDEIKPHDLKVPYGDRGGVPIEPMLTDQWYVSVKPLADVAIKAVEDGEIQFVPKQYENLYFSWMRDIQDWCISRQLWWGHRIPAWYDAEGNVYVARNEEEVRSKYNLDSAVELKQDEDVLDTWFSSGLWTFSTLGWPEQTKELKMFHPTDVLITGFDIIFFWVARMIMFTMHFVKDENGKPQVPFKTVYVTGLIRDEQGQKMSKSKGNVLDPIDMIDGISLEDLLEKRTGNMMQPQLAEKIAKATRKEFAEGIAAHGTDALRFTLAALASNGRDINWDMKRLEGYRNFCNKLWNASRFVLTNEKLDLSQGEIEFSLADRWIQSEFNRTVETFRNSLSQYRFDLCANAIYEFTWNQFCDWYLELTKPVFANGNAAQIRAASQTLVHVLEKLLRLAHPLIPFITEEIWQKVKGFVDITADSIMLQPFPQVEENCFDPEAEAEIEWLKEVIVAVRNIRAESNIAPSKGLDLLFRNLSAENAKILEKQTALLKAMAKLDNVQVLAANETAPLAVAKLVGNAELLVPMAGFINKEAELARLTKEIEKYQNEVKRIENKLSNEAFVAKAPEAVIAKEREKQAEYQSGLEKIQEQYKAIEAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_INBP3
Sequence: MKAIIVLLMVVTSNADRICTGITSSNSPHVVQTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPKCLNCTDLDVALARPKCTGTIPSAKASILHEVKPVTSGCFPIMHDRTKIRQLPNLLRGYEHIRLSTHNVINAETAPGGPYKIGTSGSCPNVTNGNGFFATMAWAVPKNDNNKTATNPLTVEIPYICTEGEDQITVWGFHSDNEAQMVKLYGDSKPQKFTSSANGVTTHYVSQIGGFPNQAEDGGLPQSGRIVVDYMVQKSGKTGTITYQRGILLPQKVWCASGRSKVIKGSLPLIGERDCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: NANA_HISS2
Sequence: MKNLKGIFSALLVSFNEDGSINEKGLREIVRYNIDKMKIDGLYVGGSTGENFMLSTAEKKEIFRIAKEEAKDQVALIAQVGSVNLHEAVELGKYATELGYDSLSAVTPFYYKFSFAEIKHYYETIIAETGNNMIVYSIPFLTGVNMGVEQFGELYANPKVLGVKFTAGDFYLLERLKKAYPNHLVWAGFDEMMLPAVSLGVDGAIGSTFNVNGLRARQIFELAKAGKVAEALEIQHVTNDLIEGILANGLYLTIKEILKLQGVNAGYCREPMTAKATEKQLAVAKELKEKFL
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELF3_MOUSE
Sequence: MAATCEISNVFSNYFNAMYSSEDPTLAPAPPTTFGTEDLVLTLNNQQMTLEGPGPQTRSQRDRTDPLAVLHLAEKASWTSERPQFWSKTQVLEWISYQVEKNKYDASSIDFSRCDMDGATLCSCALEELRLVFGPLGDQLHAQLRDLTSNSSDELSWIIELLEKDGMSFQESLGDSGPFDQGSPFAQELLDDGRQASPYYCSTYGPGAPSPGSSDVSTARTATPQSSHASDSGGSDVDLDLTESKVFPRDGFPDYKKGEPKHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVGESRN
What is the function of this protein?
Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT].  Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter (By similarity).  Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters.  Represses KRT4 promoter activity (By similarity).  Involved in mediating vascular inflammation.  May play an important role in epithelial cell differentiation and tumorigenesis.  May be a critical downstream effector of the ERBB2 signaling pathway (By similarity).  May be associated with mammary gland development and involution.  Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
What are the official names of this protein?
ETS-related transcription factor Elf-3, E74-like factor 3, Epithelial-restricted with serine box, Epithelium-restricted Ets protein ESX, Epithelium-specific Ets transcription factor 1, ESE-1.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PHEA1_SYNPY
Sequence: MKSVVTTVVTAADAAGRFLSQNDLEAVQGNIQRAAARLEAAEKLAAGLDKVTREAGDACFNKYSYLKQPGEAGDSQVKVDKCYRDLGHYLRLINYCLVVGGTGPLDEWGIAGAREVYRSLSLPTGPYVEALTYTRDRACAPRDMSPQALNEFKSYLDYVINALS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
C-phycoerythrin class 1 subunit alpha, C-phycoerythrin class I alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the periphery of the phycobilisome rod.
Protein: PRC_ECOLI
Sequence: MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
What is the function of this protein?
Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3).  May be involved in protection of the bacterium from thermal and osmotic stresses.
What are the official names of this protein?
Tail-specific protease, C-terminal-processing peptidase, PRC protein, Protease Re.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Periplasmic side.
Protein: SYT_CLOBK
Sequence: MIKITLKDGKVMEFEEGIKISDIAMKISPALYKKALAAKIDGETMDLMTELHKDSSLEILTFEDEMGKWALRHTGAHILAQAVKRLYPEVKLAIGPAIDTGFYYDFEADFTFTPEILEKIEAEIKKIIKENHKLERFELPREEAINLMKENNEDYKVELIEDLPEGEVISFYKQGDFTDLCAGPHVPSTGKVKSVKLLSLAGAYWRGNENNKMLQRIYGTAFTKKSELDEYLNMLEEAKKRDHRKLGKELDLFSIHEEGPGFPFFHPKGMIVRNILESFWREEHTKAGYQEIRTPLILNEALWHQSGHWDHYKENMYFTNIDDGDYAIKPMNCPGGILVYKNSMHSYRDLPLRLSELGIVHRHELSGALHGLMRVRCFTQDDAHLYMTKEQIKEEVVGIIKLIDKFYKLFGFEYFVELSTRPEDSMGSDEDWEIATNGLKEALDSIGKEYRVNEGDGAFYGPKIDFHLKDCIGRTWQCGTIQLDFQMPERFDLSYIGADGEKHRPVMVHRTIYGSVERFIGILIEQYAGAFPTWLAPVQVKLMNITDAQYDYLKKVEETLKENNIRVEIDTRNEKIGYKIREAQLQKVPYMLILGDKEVEAGKVAVRSRKDGDLGAISLEEFIEKIKNEIKAKTN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JAL29_ARATH
Sequence: MAQKVEAQGGNGGNQWDDGSEYDAVTKIQVAAGGNGIEYVKFTYVKNGQTEEAPLRGVKGRSFEADPFVINHPEEHLVSVEGRYNPEGLILGLTFKSNKKTSDLIGYEDGTPFTLQVQDKKIVGFYGFAGNNLHSLGAYFAPLTNVTPLNAKKLEAKGGDTGDIWDDGVYDNVRKVYVGQAQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEIDADDYIVYVEGYREKVNGMTSEMITFLSFKTYKGKTSQPIEQRPGIKFVLQGGKIVGFHGRSTDVLDSLGAYISLSPTPNLHGKWTKVDENGDGPGLRCSHDIAQVGNKIYSFGGEFTPNQPIDKHLYVFDIESRTWSISPATGDIPTLSCLGVCMVSIGSTLYVFGGRDASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLNTLDSYNIVDKKWFHCSTPGDSLTARGGAGLEVVQGKVWVVYGFNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASAALGKHIVIFGGEIAMDPLAHVGPGQLTDGTFALDTETLQWERLDKFGGEEETPSSRGWTASTTATIGGKKGLVMHGGKAPTNDRFDDLFFYGIDSA
What is the function of this protein?
Promotes simple nitriles, but not epithionitrile or thiocyanate formation.  Converts allylglucosinolate and benzylglucosinolate to their corresponding simple nitriles in the presence of myrosinase.
What are the official names of this protein?
Nitrile-specifier protein 4, AtNSP4, Jacalin-related lectin 29.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: MYOZ1_BOVIN
Sequence: MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQLRVEKFIYENHPDVFSDSSMDRFQKFIPTVGGQLGTAGQGFSYSKSSGGGQAGRSGSAGQYGSDQQHHHQGSGSGSGSGSGPGSGGAGGPGGHSGRGGALPDNQAGGEGKHITVFKTYISPWEKAMGIDPQQKVELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDISIPLDGETEEL
What is the function of this protein?
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere.  Plays an important role in the modulation of calcineurin signaling.  May play a role in myofibrillogenesis (By similarity).
What are the official names of this protein?
Myozenin-1, Calsarcin-2.
What is the protein family that this protein belongs to?
Belongs to the myozenin family.
What are the subcellular locations of this protein?
Nucleus. Cell projection, pseudopodium. Note=Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle (By similarity).
Protein: CIPK1_ARATH
Sequence: MVRRQEEEKKAEKGMRLGKYELGRTLGEGNFGKVKFAKDTVSGHSFAVKIIDKSRIADLNFSLQIKREIRTLKMLKHPHIVRLHEVLASKTKINMVMELVTGGELFDRIVSNGKLTETDGRKMFQQLIDGISYCHSKGVFHRDLKLENVLLDAKGHIKITDFGLSALPQHFRDDGLLHTTCGSPNYVAPEVLANRGYDGAASDIWSCGVILYVILTGCLPFDDRNLAVLYQKICKGDPPIPRWLSPGARTMIKRMLDPNPVTRITVVGIKASEWFKLEYIPSIPDDDDEEEVDTDDDAFSIQELGSEEGKGSDSPTIINAFQLIGMSSFLDLSGFFEQENVSERRIRFTSNSSAKDLLEKIETAVTEMGFSVQKKHAKLRVKQEERNQKGQVGLSVTAEVFEIKPSLNVVELRKSYGDSCLYRQLYERLLKDVGTSSPEQEIVT
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 1, SNF1-related kinase 3.16, SOS2-like protein kinase PKS13.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: RS13_CHLAA
Sequence: MARIAGVDIPRNKKIEIAITYIYGIGRSNGMEILRKANVNPERRVRDLTEEEVGRIREIVDREYRVEGDLRREVQLNIKRLMDIGCYRGLRHRRGMPVRGQRTRTNARTRRGRRGQAIGIKKKATKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: DN7_METS5
Sequence: MATKIKFKYKGQDLEVDISKVKKVWKVGKMVSFTYDDNGKTGRGAVSEKDAPKELLNMIGKK
What is the function of this protein?
Can constrain negative DNA supercoils.  May be involved in maintaining the integrity of the genome at high temperature.
What are the official names of this protein?
DNA-binding protein 7, 7 kDa DNA-binding protein, Mse7.
What is the protein family that this protein belongs to?
Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BX8_LOXGA
Sequence: ADSRKPIWI
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LgSicTox-beta-LOXN8, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAC_CLOAB
Sequence: MESVFDYEDIQLIPAKCIVRSRSECDTSVILGEHSFRLPVVPANMQTIIDENIALFLAQNGYFYIMHRFEPEKRLSFIKNMKSKGLFASISVGVKREEYDFIKQLAQENLSPEYITIDIAHGHSNTVIEMIQHIKKYLPKSFVIAGNVGTPEAVRELEHAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCSKAASKPIIADGGIRTPGDIAKSIRFGATMVMIGSLFAGHEESPGETIEKDGKLYKEYFGSASEFQKGEKRNVEGKKMFVEYKGPLKDTLIEMEQDLQSSISYAGGKSLDAIRTVDYVIVKNSIFNGDRIY
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: MRAZ_YERPA
Sequence: MFRGATMVNLDSKGRLAVPTRYRESLNEESQGQMVCTIDLHQPCLLLYPLPEWEIIEQKLSRLSSMNPAERRVQRLLLGHASECQMDGAGRLLIAGTLRQHAGLNKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQGLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PSAM_GRATL
Sequence: MISDSQIFVALLFALVSAVLAIRLGTDLYQ
What are the official names of this protein?
Photosystem I reaction center subunit XII, PSI-M.
What is the protein family that this protein belongs to?
Belongs to the PsaM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GLO2_NITEU
Sequence: MINVFPVRAFRDNYIWIVHNQQFALIIDPGDATPVLTWLRQQKLQPIAILCTHHHHDHTGGISLLVQKFEIPVYGPASEKIPGMTHPLAEGDTLVFPELSLELSILDVPGHTAGHIACHGQNRLFCGDTLFACGCGRIFEGNAQQMFDSLQKLTDLPDETQVYCAHEYTLDNIRFARAIDPDNPELIELESNVEEKREQNMPTLPSSLAAEKATNPFLRCNQPAIIQSASRYAGRQLTDPVSVFAAIRDWKNNFRGNTDLPM
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: THIE_LACLA
Sequence: MKNKILDLRAYFIAGPQDFPKLSIDDAIDKISVIIKSGVTVYQFRDKGTIYKNKNQRLEVAKRLQEVAQKAAVSFIVNDDVELARELSADGIHVGQDDDSVSKIRELIGQEMWVGLSVSNDMELESAQKSGADYLGIGPIYPTNSKSDAAEPIGVDHLRKMLEHNQLPTVGIGGITENSLTELSKIGLGGVAVISLLTESENYKNMVQKIKQNIR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: PTH_BURMS
Sequence: MIKLIVGLGNPGAEYTATRHNAGFWLVDQLAREAGATLRDERRFHGFYAKARLFGEEVHLLEPQTYMNRSGQAVVALAHFFKILPTEILVAHDELDLPPGAAKLKLGSGSGGHNGLKDISAHLSSQQYWRLRIGIGHPRDLIPESARAGAKPDVANFVLKPPRKDEQDLIDAAIERALAVMPTAIKGETERAMMQLHRNGA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFEL_SALTY
Sequence: MPGVLLWFFKGVIALLLAFAVGLIVYYYLEIRPIAQTALQSASFWLSESPQTRFLRRAAAKIHPKSYTARLLYTQAGVDGHFRIAIWVFWLDSLYRDDELYAMMLAQAYYGRDSQGNAVYGTKNAALTLFHVPVTEMACQQQVQLIYMFKAPSLYRPGSARLVESSKHYMTLCQEQIQQ
What are the official names of this protein?
Uncharacterized protein YfeL.
Protein: ISPG_DEIRA
Sequence: MSFDSLPALPLDPLPDAALPTAPRRRQTVSVNVGGVMVGSAHPIVVQSMTNTDTANAEATAIQVAQLARAGSEIVRVTVNTREAAAAVPELVQRLADIGVHVPIVGDFHYNGHLLLREYPETARLLAKYRINPGNVGAGQRHDENFATMIEVAKEFDKPVRIGVNWGSLDQQVLARLMDENAAAGHPKSPTDVTIDAMIVSALDSARFAEELGLGHDKILISVKVSSAPELWQVYRQLAPLCDYPLHLGLTEAGMGMKGIVASSVALAPLLTEGIGDTIRVSLTPEPGAPRKLEVEVAQQILQSLGLRQFLPQVTSCPGCGRTTSSFFQTLAQKIQDFIRESMPEWKAKYPGVEDMQVAVMGCVVNGPGESKHANIGISLPGTGEDPRAPVYQDGKLLTTLKGPRIAEEFQELLEKYVEERYGQGVAQG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: MNMG_LATSS
Sequence: MREYDAAHYDVIVVGAGHAGSEAALAAARMGRETLLLTINLDMVAFMPCNPSLGGPAKGIVVREIDALGGQMGRNIDKTYIQMRMLNTGKGPAVRALRAQADKHAYHRTMKRTIETTEHLTLRQGIAESLIVEDGVCKGIVTNTGARYSADSVILTAGTASRGKIIIGELTYSSGPNNSIPSIKLSESLEDNGFVLTRFKTGTPPRVDGTTIDFSKTEEQPGDKEPNHFSFETPDSAYLKDQLSCWMTYTNDTTHQVIRDNLDRAPMFTGVIEGVGPRYCPSIEDKIVRFADKPRHQIFLEPEGRETEEYYVGDFSTSMPEEIQHKMIHSIEGLENAQMMRPGYAIEYDVVEPWQLKPTLETKVVENLYTAGQMNGTSGYEEAAGQGLMAGINAALKQTGRDPFILDRSEAYIGVLIDDLVTKGTKEPYRLLTSRAEYRLMLRHDNADLRLTEKGHELGLINDDRFDSYEVKKAAVEAELARLEKIRLKPTPEIQAFLAAKGEAPLKDGVLASDFLKRPEVKYADLIQFIPAVEGIDNRVVEQVEIQVKYAGYIDKEKAKIAKLKRMEAKKIPANIDYDAIEGLATEGRQKLQKIQPETLAQASRIGGVNPADIGILSVYIQQGKIAKVK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.