PharMolix/UniProtQA huggingface dataset:
Protein: RLMH_BURP1
Sequence: MKLHIVAVGHKMPGWIASGFDEYAKRMPPELRIELREVKPELRSGSRTADSVMAAEQQRIEAALPKNARVVALDERGRDWTTMQLAQALPAWQQDGRDVAFVIGGADGLAPALKSRAELLLRVSSLTLPHGMVRVLLAEQLYRAWSITQNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_LEVBA
Sequence: MKMIVGLGNIGPQYDNTRHNTGFMVVDAFAQQHGIALTTRKMDARFGSGLVNGEKVLVVKPTTFMNESGRAVHPIMDYFKIDVADVMVVQDDMDLPLGRIRLRDHGSAGGHNGIKSIIAHVGTQNFGRLKVGIAHPQQHTVVDYVLGKFTTDQRPVFNQAADRAVAALDDWVAGSDFMQLMNQYN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_DECAR
Sequence: MTFKTPDLCDEFESELGKTVRVVTPMFQRYGGRTSFSGQIVTLKIFEDNSLVREVFGEDGKGKVLVIDGGGSLRCALVGDQLAILANKNGWEGVVVYGCIRDSGDINGIDIGVRALNTHPQKTLKKGVGDKNVAVTFGGVTFNPGEYLYADEDGVLVSGKALT
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: FOSB_BACCQ
Sequence: MLKGINHLCFSVSNLEDSITFYEKVLEGELLVRGRKLAYFNICGVWIALNEEIHIPRNEIHQSYTHIAFSVEQKDFERLLQRLEENDVHILQGRERDVRDCESIYFVDPDGHKFEFHSGTLQDRLNYYREGKPHMTFY
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_PHOV8
Sequence: MSNNLIIINAHIVTPQGRTARKGEAMNELLNIPCGTVRVTDGIITYVGENRISHEKPGYKVLDARGNVLLPGFVDSHTHLVFGGFRPDEFIWRLNGDSYMSIMERGGGIINTVRATREASFEELKHKAEWFLDTMSRMGVTTVEGKSGYGLDRDTELKQLSIMQAINECPDRKVDIATTFLGAHALPEEYKGRSDAYIDFLINEMLPMIHQKQLAENCDIFCEKGVFTVEQSRKLLKAAQALGFGTKLHADEIVSFGGAELAGELKALSADHLLQASDEGIKALAQNNVVATLLPLTAFTLKEPYARGRKMIDSGCAVALATDLNPGSCFSGSIPLTFALACIYMKLTVAEAITAITLNGAAALGRADRIGSIEAGKQGDFVLLGTDNPHILPYYTGMNAVKLTIKGGRILHSN
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGO1_CAEEL
Sequence: MDAKTAQSIFGGIVAAKKRPSKEVPEPTINFKSANDSLVKKNLLLKQQVVQCTKTIEKLRNENVALRQKNQELIDGTLEQRIELIVEQRLKFRLAHAAVLHKKLVQNIQQTGLELDGLFKDLEPEPSGLNTRRPPKLELNLERVDEIPFCQSSMQGEIDENEIRFDNNSSQSTSSIQNAVNGTPRKKQSVGKGRRSELFQSFNADSSIVEEASTIPTNRRAPMLIAPSSTPAGPSKPTARKPPTPRFKKPSTPALAPQSDDTELSSTIQVRRQRSAKMNIKSLKEPSGKDKLRRPGKHDEPMPYINTFF
What is the function of this protein?
Component of cell cycle checkpoints, which ensures chromosome segregation during meiosis and mitosis (PubMed:18923084).  During meiotic prophase, it is involved in the regulation of the synapsis checkpoint, which monitors whether homologous chromosomes have synapsed, and the DNA damage response (PubMed:30293721).  Plays a central role in chromosome cohesion during cell division by preventing premature dissociation of cohesin complex after prophase, when most of cohesin complex dissociates from chromosomes arms (By similarity).
What are the official names of this protein?
Shugoshin.
What is the protein family that this protein belongs to?
Belongs to the shugoshin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome. Note=Localizes to nuclei prior to entry into meiotic prophase and late meiotic prophase (PubMed:30293721). Localizes to the short arms of bivalent chromosomes from late diakinesis until anaphase II (PubMed:18923084).
Protein: CWP05_PHAVU
Sequence: EDPVRFNLG
What are the official names of this protein?
65 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RS7_MYCBO
Sequence: MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLKGKKSLAERIVYGALEQARDKTGTDPVITLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLALRWLVGYSRQRREKTMIERLANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ITRY_ENTCO
Sequence: KELLDSDGDILRNGGTYYILPALRGKGGGLELAKTGDETCPLNVVQARGETKRGRPAIIWTPPRIAILTPAFYLNIEFQTKDLPACLREYSRLPREEEQHSEVKLAPKEEAAAFGXEKLKPYRDDYKIVYCEGGSDDDSCKDLGISIDDENNRRLVVKDGDPLAVRFVKAHRRG
What is the function of this protein?
Inhibits trypsin and chymotrypsin with a 1:1 stoichiometry, with dissociation constants of 1. 56 nM and 120 nM respectively.  Inhibits plasma kallikrein, factor XIIa and plasmin with dissociation constants of 5. 0 nM, 150 nM and 18 nM respectively.  Does not inhibit factor Xa, thrombin, tissue kallikrein or cysteine proteinases such as papain and bromelain.
What are the official names of this protein?
Trypsin inhibitor, EcTI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
Protein: ISPE_HAES1
Sequence: MKNYQFSTALLSSQIQGKKLRFPCPAKINLFLYITSQRPDGYHELQTLFQFLNFGDWLSIEIRTDGKIILTSEIPHLKNEDNLIYRAAKLLQQKTGCTLGANLHLDKILPIGGGVGGGSSNAATALVALNYLWNTQLSLSTLAEIGLQLGADVPVFVYGKAAFAEGVGEKLTFCQPPQKWFLVLKPETSISTAIIFKDPNLPRNTPKRPLAELLITKYENDCEKVVLNHYSEVEEALGWLLQYAPARLTGTGACVFAEFANEQAAQSAFLDKPEKYVGFVAQGTNISPLHQMIEYLSQQKQTLCLPNNTNSRG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RS2_CLOBL
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMAPYIFTERNGIYIIDLQKTVKKVEEAYNFLRSVAEEGKDVLFVGTKKQAQEAIEEEAKRSEMHFVNNRWLGGMLTNFTTITARINKLEELDKMEEDGTFEVLPKKEVIKLKNEREKLEKNLGGIRKLDANNVGAMFIVDPRKEKNAILEAKRLGIPVVAIVDTNCDPDEVDFVIPGNDDAIRAVRLIAAKMADAVLEGRQGEQLAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: OTOGL_HUMAN
Sequence: MNIVRKLNLMIPWSIFLLHVLLFSLQEYICASSILMGTSKNGFNENRQKRALLAAQFEATSPRYFFHDAINWGESKIKGSCPYECLNGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDDETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNIGYAAHCDVIHQELFAPCHIYISPGLYYQLCRHDACKCGSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGMAEHRGKCYVPESCPCIWKDWEYLSGEVIATPCYTCVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYNEGLGEGPYMLASYGQSGLVLGANMTSRSVFCLPRSSVHTSLFFYFMITPGLFKEKVSSLALVSLESAERPNYFLYVHDNDTLSLELWEANSAFHRRATFFHHQGLWIPGYSAFELYSKKGFFIIFTDSSVKASKYDDSEEFKHSSSFSIEEIQAAVPYRKMCEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVIPTEPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYDCSQYICLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQNGNSLKKLAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDFCEKMWINYTYFWNYECDALSAYVALCNKFDICIQWRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCEREAEVVMGIIDKWTCCSKEVCGCDTTLCETSIPTCTNSQKLIVGHSPLSCCPQYKCECDPLKCPSISTPECREDQFMIQVRQEEPCCFSPFCVCESCTKPVPLCHDGEFLTVDLNSTHFCCPQYYCVCEPNLCPMPLLNCAEDMNLVKENVSGQCCPTWHCECNCENLIMPTCEVGEFTAIDHNFQSDCGCIQYLCEKDDVCVFQEVSVLNPGQSMIKYLEEDFCYAIECLEEKDNHTGFHTLNFTLVNCSKKCDVHQVYTPSPSDYGCCGTCKNVSCKFHMENGTSVVYAVGSTWHYNCTTYECVKTDEGAIILNYTMVCPPFNETECKMNEGIVKLYNEGCCKICKREERICQKVIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCKCCRENGVRNLSVPLYCSGNGTEIMYTLQEPIDCTCQWN
What are the official names of this protein?
Otogelin-like protein.
What is the protein family that this protein belongs to?
Belongs to the otogelin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NCAP_I89A4
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTVERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVGGRWMRELVLYDKEEIRRIWRQANNGDDATRGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGIGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVSSGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDNMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFEKSTVMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LCE3A_HUMAN
Sequence: MSCQQNQQQCQPPPKCPAKSPAQCLPPASSSCAPSSGGCGPSSERSCCLSHHRCRRSHRCRCQSSNSCDRGSGQQGGSSSCGHSSAGCC
What is the function of this protein?
A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable).  Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species.  Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens (PubMed:28634035).
What are the official names of this protein?
Late cornified envelope protein 3A, Late envelope protein 13.
What is the protein family that this protein belongs to?
Belongs to the LCE family.
Protein: RNH_SHEAM
Sequence: MSELKQIRIYTDGSCLGNPGPGGYGVVMIYKQHRKELADGFALTTNNRMELLAPIVALESLKEPCDVILTSDSQYMRQGITEWIHGWKKKGWVTASKTPVKNVDLWQRLDAAAAKHKVDWRWVKGHAGHAENERCDTLAREAAEAKPTQIDKGYQP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_PROM0
Sequence: MPLLNSVTTPYAEALLQVVNENSQTEEMVSEVKQLLELINNSPELEKALSSPILETDAKKKIINEIFSKKVNSSLLNFLKLLADRQRIGILTSILDRFLEIYRENSNIALATVTSAVELTDEQKGLITKKIINIAGTEKLELVTKIDPSLIGGFVASVGSKVIDASLASQIRKLGLSLSK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RITA1_RAT
Sequence: MQALHLQHRNPRSYRVKARASYVDETLFGSPTGTRPTLPDFDPPWVQNCNRSRGVSPGPPKVSLAKRDCESPSSRGSTPNLTPRKKNKYRLIGHTPSYCDESLFGSRPQGTSKERSRTAVEDAAKLRTLFWTPPATPRGSHSPRPRETPLRAIHPTGPPRTEPRVATGSQMVSRDGLDAPRSLGQRRSYSLTHLAVPSTGHPASTAPQTNGPWSPRPYTSGATVQSPLVTRKVCSGSVSGPTTPQRGACPQKPKPPWK
What is the function of this protein?
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway.  Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription.  May play a role in neurogenesis (By similarity).
What are the official names of this protein?
RBPJ-interacting and tubulin-associated protein 1, RBPJ-interacting and tubulin-associated protein.
What is the protein family that this protein belongs to?
Belongs to the RITA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear (By similarity).
Protein: DNLJ_LIMRD
Sequence: MSEKQTPVKELTLQEAQDEIKPLRAKLTKWGKEYYEQDNPTVEDHVYDRAYQRLVQLEEQFPQLVSADSPTQRVGGATESQLTKVRHEIPMLSMGDVFSIEELMDFNQRQQENRDVEVEPEYNLELKIDGLSLSLVYENGKLVQGSTRGNGTIGEDVTANVRTIKSVPAELPEPLSIEVRGECYMPKAAFAKLNAKREAEGLPVFANPRNAAAGSLRQLDPKVTAQRELDTFMYYVPEYQKIGVKTQAEALDRMRELGFNVNPNNRVVHNRDEIEKYIEEYTAQRDKLTYGIDGIVEKVNDLDTEVALGNTVKVPRWEIAYKFPPEEQATIVRDIVWTVGRTGNVTPTAVMDPVQLAGTTVSRASLHNPDYLREKDIRIGDTVYLHKAGDIIPEISKVDLTKRPADSVEYEIPTKCPVCGSELVHLDGEVALRCINPMCPAQIKEGLAHFASRNAMNIDGLGPRIIEQLWDKELIHDVAGLYRLNHDQLLTLDKFGEKSTANLLTSIDNSRNNSVERLLFGLGIRHVGAKAARIIMEHFGDLDSLMKADADEISAISGIGPTIGESIVTYFANQQVVKLIDELREVGVNFAYLGSRSNANPDSEWNGRRVVLTGKLTEMTRGEAKSWLENHGAKVTESVSKKTDIVIAGADAGSKLTKAQNLGIDVWNEQQFSQAMKEEQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SPL6_ORYSJ
Sequence: MEAARVGAQSRHLYGGGLGEPDMDRRDKRLFGWDLNDWRWDSDRFVATPVPAAEASGLALNSSPSSSEEAGAASVRNVNARGDSDKRKRVVVIDDDDVEDDELVENGGGSLSLRIGGDAVAHGAGVGGGADEEDRNGKKIRVQGGSPSGPACQVEGCTADLTGVRDYHRRHKVCEMHAKATTAVVGNTVQRFCQQCSRFHPLQEFDEGKRSCRRRLAGHNRRRRKTRPEVAVGGSAFTEDKISSYLLLGLLGVCANLNADNAEHLRGQELISGLLRNLGAVAKSLDPKELCKLLEACQSMQDGSNAGTSETANALVNTAVAEAAGPSNSKMPFVNGDQCGLASSSVVPVQSKSPTVATPDPPACKFKDFDLNDTYGGMEGFEDGYEGSPTPAFKTTDSPNCPSWMHQDSTQSPPQTSGNSDSTSAQSLSSSNGDAQCRTDKIVFKLFEKVPSDLPPVLRSQILGWLSSSPTDIESYIRPGCIILTVYLRLVESAWKELSDNMSSYLDKLLNSSTGNFWASGLVFVMVRHQIAFMHNGQLMLDRPLANSAHHYCKILCVRPIAAPFSTKVNFRVEGLNLVSDSSRLICSFEGSCIFQEDTDNIVDDVEHDDIEYLNFCCPLPSSRGRGFVEVEDGGFSNGFFPFIIAEQDICSEVCELESIFESSSHEQADDDNARNQALEFLNELGWLLHRANIISKQDKVPLASFNIWRFRNLGIFAMEREWCAVTKLLLDFLFTGLVDIGSQSPEEVVLSENLLHAAVRMKSAQMVRFLLGYKPNESLKRTAETFLFRPDAQGPSKFTPLHIAAATDDAEDVLDALTNDPGLVGINTWRNARDGAGFTPEDYARQRGNDAYLNMVEKKINKHLGKGHVVLGVPSSIHPVITDGVKPGEVSLEIGMTVPPPAPSCNACSRQALMYPNSTARTFLYRPAMLTVMGIAVICVCVGLLLHTCPKVYAAPTFRWELLERGPM
What is the function of this protein?
Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'.
What are the official names of this protein?
Squamosa promoter-binding-like protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLYA_FRATM
Sequence: MFSFEKNSLKNTDKEIFDAIELEVKRQHEHVELIASENYASPAVMEAQGSQLTNKYAEGYHGKRYYGGCEFVDIAEKLAIERAQQLFGVDYANVQPHSGSQANAAVYNAVLKPGDTVLGMDLGAGGHLTHGSKVNFSGKIYNSIQYGLDENGDIDYEQVAQLAKEHKPKMIIAGFSAFSGIINWQKFREIADSVDAVLMADIAHVAGLVAAGVYPNPFPYVYVATTTTHKTLRGPRGGLILCNNNPELAKKFQSAIFPGIQGGPLMHVIAAKAVAFKEALEPSFVDYQKQVLKNAKAMEKVLKQRGINIISGGTSNHLLLLDITNTGFSGKEAEAALGRANITVNKNSIPNDPRSPFVTSGLRIGSPAITTRGFKEKECELVANLLADVVFNCGDEKVENETAAKVLDLCDKFPVYK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTN_ECO57
Sequence: MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYVSADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRIDPRPYEANLAKSEASLAALDKQIMLTQRSVDAQQFGADSVNATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTAQRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGASAVANLEPQ
What is the function of this protein?
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
What are the official names of this protein?
Multidrug resistance protein MdtN.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: HIP34_ARATH
Sequence: MNKQDVMKLQTCVLKVNVHCEGCKHKVKKQLQKIEGVYSVKADVEQGRVTVTGNIDPALLVKKLSKSGKHAEILGGGGGGGGGGGKGFPNLNGQFANLNMGGNNKPKGGKESNQVKGKAGGGGGGGQNHGHGQPMQLNPQQIQQMMMMKAAHGGGGGGQMKMPPMAAKDQKKSVKFADDEDDEFSEDDYDDEDFSEDDYDDDEFDDDEDDDDEMGHGHGHGGGGGNHMPPNKMMMPNKMMPQMGGHHGNGGGPKGPNEIMMMMNGFKGGGGGGKKGGGGGFEIPVQMKGMGEGKNGKDGKKGKGGEKGKKEGKENKGGGKTGKTDAKSGGGGLLGFFKKGKSGNGDEKKSAGKKDGHGGNKVKSHGGGGGVQHYDSGPKKGGGGTKGGGHGGLDIDELMKHSKGGGGGGNKGNHNHSAKGIGGGPMGPGGPMGPGGPMGQGGPMGMMGPGGPMSMMGPGGPMGPMGGQGGSYPAVQGLPMSGGGGYYPGPPQASQQMNQQQYMQMMMNQQQQQQQQQQAVAHGGYGGGHGGDMYHPMMYARPYPAVNYAHPPPMPPPHSDSYTHMFSDENPGSCSIM
What is the function of this protein?
Heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 34, AtHIP34.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: RECA_ECO8A
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOM1_YEAST
Sequence: MAPPTTIRTRDQALAPLATLDSQTNCRLKELVQWECQFKGAEYVCSPFKRLFEHCIAPDKSATNYEVTDTYTNS
What is the function of this protein?
Non-catalytic component of the mitochondrial inner membrane peptidase (IMP) complex.  IMP catalyzes the removal of signal peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space.  SOM1 facilitates cleavage of a subset of IMP substrates.
What are the official names of this protein?
Protein SOM1, mitochondrial, Mitochondrial inner membrane protease subunit SOM1.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.