PharMolix/UniProtQA huggingface dataset:
Protein: RL13_SPOFR
Sequence: MGKGNNMIPNGHFHKDWQRFVKTWFNQPARRHRRKQNRIKKAKAVAPRPAAGPLRPVVRCPTIRYHTKVRAGRGFTLREIRAAGLNPAFARTIGIAVDPRRRNKSVESLQVNVQRLKEYRARLILFPKGKKVLKGEANEEERKLATQLRGPLMPVQQPAPKSIARAITEEEKDFKAYQYLRGARSIAKLVGIRAKRLKDAAENPDDVTKAPTAVKRNKT
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  As part of the LSU, it is probably required for its formation and the maturation of rRNAs.
What are the official names of this protein?
60S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_HUMAN
Sequence: MALQLGRLSSGPCWLVARGGCGGPRAWSQCGGGGLRAWSQRSAAGRVCRPPGPAGTEQSRGLGHGSTSRGGPWVGTGLAAALAGLVGLATAAFGHVQRAEMLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRRPGDMKTKMELLILETQAQVCQALAQVDGGANFSVDRWERKEGGGGISCVLQDGCVFEKAGVSISVVHGNLSEEAAKQMRSRGKVLKTKDGKLPFCAMGVSSVIHPKNPHAPTIHFNYRYFEVEEADGNKQWWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDLYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEVFRFVQSCARAVVPSYIPLVKKHCDDSFTPQEKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPSENSKEAEILEVLRHPRDWVR
What is the function of this protein?
Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX and participates to the sixth step in the heme biosynthetic pathway.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial, COX, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: VA2_SOLSV
Sequence: MKSFVLATCLLGFAQIIYADTEKLKILRKDIAKCARTLPKCVNQPDDPLARVDVWHCALAKSGVFDDPDPAAIKKKYKKFCAIAVTDPANVENCKKVTSRCVDKETQCSKSNRQKAINIAACILRSGVTETTVLAREK
What are the official names of this protein?
Venom allergen 2.
What is the protein family that this protein belongs to?
Belongs to the ant venom allergen 2/4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DTD_LISMF
Sequence: MRVLLQRCYEASVSVEEEVISEIAGGLCLLVGFTHKDTPETVDYMAKKIVGLRIFEDESEKMNISLAERGGAILSVSQFTLYADVSRGKRPSFTKSAPAEKAETLYDLFNQKLTEAGFIVETGVFGAMMDVKIVNHGPVTIMLDSDEMRK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_SYNP6
Sequence: MNAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPNAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTEYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFHPVVERDRLT
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEBS_ECO57
Sequence: MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEINSHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANVMQGIWQMTKQGDAITGSMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLKEWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFYPQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVLLLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFTLLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAAFYFGAAVILTILAVEWLDSRLLWDAHESGNARFDD
What is the function of this protein?
Component of a transport pathway that contributes to membrane integrity.
What are the official names of this protein?
Intermembrane transport protein YebS.
What is the protein family that this protein belongs to?
Belongs to the PqiA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G6PI_MYCCT
Sequence: MIKVNLDHTDININKVADLNKIKEIHQMIFNKTGKGNDFLGWLNWPVNFNKTEYEQMKLVANDLKNQIEVLVVIGIGGSYLGCRAADEMIRGLYHQNKVELIYTGNTMSSTYIYQVVEYLKNKNFGICVISKSGTTTEPGISFRVFEKLLVDKVGLEKAKSLIVAITDKNKGALKQLAEKKGYQTFVIPNDIGGRFSVLTPVGIFPLLVSGINTDKIFQGALKAKNDLINDDLSNQAYKYAVVRNYLYNQGYKTEALISYELQLQMLTEWWKQLFGESEGKENKGLLPSSMIFSTDLHSLGQWVQEGPRNVMFETIIKIEKPNHDLNVPIDEDNYDGLNYLTKKSFHQINQTALKGVIQAHSVTGKMPNIVLEFEKMDDEQFGYLVYFFELALAMSAYLLDVNPFNQPGVEVYKYNMFKLLNKPGIK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_FRATH
Sequence: MQINISNLDVKNHLDKFIEDRLEYEFCKQDKYLYLENDNLKLHYNNKELFIDFNDSEILNRINPKTKKCSVVQAIEGRSKAKLTILDTTAGLGRDTFTLAARGHTLLTLEKDSYLYLLLKDALQRAQQINYLKEIANRITLINIDSNEYILTTDKSFDCVYVDPMFPPRKKSAKVKQGMQILHQVGFNDEVSNSNLLDNIIQTQISPKAVVKRPINAEFLSNKKPSSQLKGKTNRFDIYSL
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1494_STRZP
Sequence: MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAVRHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS
What are the official names of this protein?
UPF0291 protein SPP_1494.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUS29_BOVIN
Sequence: MTSGESKTGLKNVYPSAKKLLPKVEEGEAEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDETTALDRYGLQKAGFTHVLNAAHGRWNVDTGPDYYRDMAIEYHGVEADDLPSFDLSVFFYPAAAFIDAALRYDHNKILVHCVMGRSRSATLVLAYLMIHRNMTLVDAIQQVAKNRCVLPNRGFLKQLRELDRQLVQQRRQAQQGEDAEKCEQEP
What is the function of this protein?
Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity).  Involved in the modulation of intracellular signaling cascades.  May regulate glucose metabolism by activating, AMPK, an energy sensor protein kinase.  Affects MAP kinase signaling though modulation of the ERK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity).
What are the official names of this protein?
Dual specificity phosphatase 29, Dual specificity phosphatase DUPD1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYY_THEKO
Sequence: MDIERKIELIKKKPTEELLTEENLRHLLEVGAPLQHYIGFEISGYIHLGTGLMAGAKIADLQKAGVKTRIFLADWHSWINDKLGGDLEVIQKVALTYFKEGMKQSIKVMGGDPDKVEFVLASEILDKGDYWQTVIDISKNVTLARMLRSITIMGRQMGEAIDFAKLIYPAMQVADIFYQGVTIAHAGMDQRKAHVIAIEVAQKLKYHPLEWKGEKLKPVALHHHLLLGLQEPPVWPIESEEQFKELKTQMKMSKSKPYSAVFIHDSPEEIKQKLRKAFCPAREVKYNPVLDWAEYIIFREEPTEFTIHRPAKFGGDVTYTTFEELKKDFAEGKLHPLDLKNAVAEYLIELLKPVREYFEKHPEPLELMREIKITR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAMP_MACFA
Sequence: MKTQRDSPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQKSPEDCDFKEDGLVKRCVGTVILNQARDSFDISCDKDNRRSARLGNFFRKVKEKIGGGLKKVGQKIKDFLGNLVPRTAS
What is the function of this protein?
Exhibits antimicrobial activity against E. coli and B. megaterium (in vitro).
What are the official names of this protein?
Cathelicidin antimicrobial peptide.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCUP_CHLTE
Sequence: MLKNDLFIRALKRQATPRTPIWVMRQAGRYLPEYRAVREKTDFLTLCKTPELACEVTIQPVDLMGVDAAIIFSDILVVNEAMGMNVEIIETKGIKLTPPIRSQADIDKLIDPDIDEKLGYVLDAIRLAKKELNDRVPLIGFSGAAWTLFTYAVEGGGSKNYTWAKKMMYREPKMAHQLLQKISDCISAYLVKQVEAGADAIQIFDSWASALSEDDYREFALPYIKQNVAAVKAAYPEIPVIAFAKDMNTILSDIADCGADAVGLGWNIDIAKARKELNDRVCLQGNMDPTVLYGTPEKIKSEAAKVLKQFGQHNDHSGHVFNLGHGILPDVDPANLKCLVEFVKEESAKYH
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YRKC_BACSU
Sequence: MYYNPFSPQCYYYVTVPMYNDGRSVYWTIPNEMEKVHRGADLRSSYEDRNLLLKDYGPKPFVVNINRATKQNNTFRTALWTGKHFQVTLMSLGIGEDIGLEIHPNVDQFLRIEQGRGIVKMGKSKDHLNFQRNVYDDSAIVVPAGTWHNVINTGNTPLKLYSIYAPPNHPFGTVHETKADAVAAED
What are the official names of this protein?
Uncharacterized protein YrkC.
Protein: WTF30_SCHKA
Sequence: MKNKYYPLRSSIDELSTKNDNEIDLEKGPLPEYNSEDGSTLPPYSENLKLKDPKQMGANNPNLFNTDESTTPPDYGEDSLSHRENHSSGTTDNSSPFLIKLLISFIPIFVLNVPAVCYLTYKDALFKDYGKDEWVYFGMWCASCLMIFISLWCFYETWTQAVAQCVKVTAISLAKCVKVISIGLFNIRREMMIIIWILWLIICCILFVYIKSGDLNLNKALIYSTCTISAVLLLIVSSVCIPFWTFERTLAKLAKVFLLQSGIVLVLNGTMFLRGKHFEWTGCEIEASVLFIMGNVLFLCEMECPGALRRMPKSIRNGIASFLGGIANAIRGANDNNDIPLGEMDVESEV
What is the function of this protein?
Forms toxic aggregates that disrupt spore maturation.
What are the official names of this protein?
Meiotic driver wtf30.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
[Isoform 1]: Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Note=Contained within spores expressing the isoform and localizes isoform 2 to the vacuole. SUBCELLULAR LOCATION: [Isoform 2]: Ascus epiplasm. Cytoplasm. Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes in trans to all spores within an ascus. Localization to the spore vacuole is dependent on isoform 1.
Protein: TVB76_HUMAN
Sequence: MGTSLLCWVVLGFLGTDHTGAGVSQSPRYKVTKRGQDVALRCDPISGHVSLYWYRQALGQGPEFLTYFNYEAQQDKSGLPNDRFSAERPEGSISTLTIQRTEQRDSAMYRCASSL
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 7-6.
What are the subcellular locations of this protein?
Cell membrane.
Protein: IWS1_EMENI
Sequence: MSASPSRSPESKPAGNTPPIDVDVENEQNVDAEEAVQPPTPGAGGDDADADDNDAKPAVDNEIDNDNTNLNENEGQNELNEDNLGDSDDESILSEVDEAQFEDFDPENVDIEDRPQLDIDEENLKLIGRHKRKRTEEEGTSKRKKEGRRRKSRRYAEEEEGGSDREAGGKRRKSKKAELEEDEETLDPATRRRRALDRAMDEALKKPTKRRARKQDGIDLEQMADAEIEDMRKRMTHAAQMDAINRREGKPAMHKLKMLPEVVSLLNRNQYVNSLVDPEINLLEAVKFFLEPLDDGSLPAYNIQRDLMTALGKLPINKETLIASGIGKVVVFYTRSKRPEPGIKRMAERLLAEWTRPILQRSDDYSKRVYQEAEFDPTYVLSPFLLKITSRVKSVQDSAAEARARELLPPRLANRARAEISHTSYTVVPKPTVVQESKFARPLGASGEDRFRKMRARQIAATKGQGARR
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
What are the official names of this protein?
Transcription factor iws1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCPB_STRT2
Sequence: MSSHLARLEALLFVAGEDGLSLRTMAQLLEIPVTGLTQSLEKLQAKYEADEDTALCLLESSNTYKIVTKPDFACLLRDYSKTPINQSLSRASLEVLSIVAYKQPITRAEVDDIRGVNSSGAIAKLQAFGLIREAGKKDAVGRPNLYATTDYFLDYIGINSLDELVAIDQLELEEQETSLFREDAPEDLEDLDN
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: TX21B_PHONI
Sequence: MWLKIQVFVLALALITLGIQAEPNSGPNNPLIQEEARACADVYKECWYPEKPCCKDRACQCTLGMTCKCKATLGDLFGRR
What is the function of this protein?
Antagonist of L-type calcium channels (Cav1/CACNA1).
What are the official names of this protein?
U6-ctenitoxin-Pn1a, U6-CNTX-Pn1a, Neurotoxin Pn3A.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family. 01 (Tx3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_SALPK
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDGAYIDALAKSARESFARHGEPDVLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEVGGKKYAYIPALNATPEHIDMMLKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_RHIL3
Sequence: MPKEEVLEFPGIVTELLPNATFRVKLENEHEIIAHTAGRMRKNRIRVLAGDKVLVEMTPYDLTKGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRPH_MESAU
Sequence: MLVVLLTAALLAEHATIYEDSISQLSEEEQQGQDPGQLHQRPGQFPPQPSASDEEGDDDGEEDGNAPEGPPQQGGDHQKPRPPKPGNQQGPPQQEGQQQNRPPKPGNQEGPPQQEGQQQNRPPKPGNQEGPPQQEGQQQNRPPKPGNQEGPPQQEGQQQNRPPKPGNQEGPPQQGSEEQSTSL
What are the official names of this protein?
Acidic proline-rich protein HP43A.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSP_AGRVS
Sequence: MTTPTEFQFTDYQPYDFANRRHIGPSPAEMDEMLKTVGYDSLDGLIAATVPASIRQSAPLVWGKAMSEREALDKLRETANKNKALTSLIGQGYYGTITPPVIQRNILENPAWYTAYTPYQPEISQGRLEALLNFQTMICDLTGLDVANASLLDEATAAAEAMAMAERVAKSKAKAFFVDSNCHPQTIAVIQTRAEPLGWGVVVGNPFTDLNPGEVFGALFQYPGTHGHVSDFTPLINALHNAQAIAAVAADPLALLLLKSPGEMGADIAIGSSQRFGVPVGYGGPHAAYMAVKDAIKRSMPGRLVGVSVDSRGNRAYRLSLQTREQHIRREKATSNICTAQVLLAVMASMYAVFHGPQGLKAIAQQVHQKTVLLAKGLEKLGFTIEPETFFDTITLEVGHMQGLILRAAVAEGVNLRKVGTTKIGISLDERTRPATLEAVWRAFGGNFAVGDFTPDYRLPTSLLRTSQYLTHPIFHMNRAESEMTRYIRRLSDRDLALDRAMIPLGSCTMKLNATAEMLPITWPEFSDIHPFAPADQALGYQEMIDDLSEKLCAVTGYDAISMQPNSGAQGEYAGLLTIRNYHLAKGDTHRTVCLIPTSAHGTNPASAQMAGMLVVPVKALDNGDVDLADFRTKAEQHSTNLSCCMITYPSTHGVFEETVREICEITHAHGGQVYLDGANMNAMVGIARPGDIGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLTPYLPGHVETDGRPGAVSAAPYGSPSILPISWSYCLMMGGEGLTQATKVAILNANYIAARLTGAYDVLYTSASGRVAHECIIDTRPLADSAGVTVDDVAKRLIDCGFHAPTMSWPVAGTLMIEPTESETKAELDRFCTAMLAIREEARAIEDGRMDKTNNPLKNAPHTVEDLVGEWDRPYSRDQACYPPGAFRVDKYWSSVNRVDNVYGDRNLVCTCPPMSEYAEAAE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: UREG_HAEI8
Sequence: MSNTVATMINKRNIMRNYIKIGVAGPVGAGKTALIEKLTREIASKYSVAVITNDIYTQEDAEFLTKNSLLPPERIMGVETGGCPHTAIREDASMNLEAVDEMVTRFPDVEIVFIESGGDNLSATFSPDLADVTIFVIDVAQGEKIPRKGGPGITRSDLLVINKTDLAPFVGVDLSVMERDARRMRNGQPFIFTNLMKKENLDGVIGWIEKYALLKNVEEPASLVR
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_CAUVC
Sequence: MKVILLERVEGTGVLGDEVTVKDGFARNYLLPRGKALRATKANLATFEAQRAEIEARNVKNRESAAKNGEALDGTQYILIRQAGESGQLYGSVAGRDVADAIKAEGGKVDRSMVVLDKPIKTLGVHEVKVKLHAEVTITVTLNIARSQDEAERQARGENVINSQFEEDRAAEAEAAQDMAEGGAGSFEGDHYEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: TSX_SHIFL
Sequence: MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMSLSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLGDDSGNAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGNFNVRSTGWGGYLVVGYNF
What is the function of this protein?
Functions as substrate-specific channel for nucleosides and deoxynucleosides.
What are the official names of this protein?
Nucleoside-specific channel-forming protein Tsx.
What is the protein family that this protein belongs to?
Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RL3_ECO7I
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: H31_TETPY
Sequence: MARTKQTARKSTGAKAPRKQLASKAARKSAPATGGIKKPHRFRPGTVALREIRKYQKSTDLLIRKLPFQRLVRDIAHEFKAELRFQSSAVLALQEAAEAYLVGLFEDTNLCAIHARRVTIMTKDMQLARRIRGERF
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3, H3S, Major histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to both the large, transcriptionally active, somatic macronucleus (MAC) and the small, transcriptionally inert, germ line micronucleus (MIC).
Protein: RL25_RALSO
Sequence: MKVVAFERSVQGTGASRRLRNAGKTPAIIYGAGAEPKLIELDHNALYHALKKEAFHSSILDIEVAGKVEKALLRDFQLHPFKQLVLHVDFQRVSATEKIHVKVPLHFLNQETAPGVKLGHGIVNHILNDVEVSCLPADLPEFIEVDLGNLEIGQTLHISDLKLPKGVTIVTHGGDENPAVANISVPAGEVSAAAAESAGEGDKPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.