PharMolix/UniProtQA huggingface dataset:
Protein: PB1F2_I02A2
Sequence: MEQEQDTPWTRSIEHINTQRRGNGQQTPKLEHPNSIQLMDHYPRITSRADMHKQIVCWKQWLSSKNPTQGSLKTHVLKRWKLFSKQEWTN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: AZOR_MYCPN
Sequence: MKKVIIIDASVSPSGSYTHLLLERFLATFQAKNKDVELSTWNLNELPVGQISYNTQNAGTFFSVENSDKYIDALKAAHGVIILAPMTNFNYPATLKNFIDHVFVANKTFKDKYVTKGASSGMLGNLKVVVLGSQGAPLGWYPWGDHVNSLRGLFGFAGVASFASVIIDGTKLLYKDKSKSEVVDMFAKQVDAIANEF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: FMO4_RABIT
Sequence: MAKKVAVIGAGVSGLTSIKCCLDEDLEPTCFERSNDIGGLWKYTETSKDGMTRIYWSLVTNVCKEMSCYSDFPFQEDYPNFMSHSKFWNYLQEFAEHFDLLKYIQFKTTVCSVTKRPDFSKTGQWDVVTETEGKQHRAVFDAVMVCTGKFLNPRLPLESFPGILKFRGQILHCQEYKIPEGFRGQRVLVIGLGNSGGDVAVELSRVAAQVLLSTRTGTWVISRSSNGGYPFNMMITRRCLNVIEQVLPSCFLRWINERQMNKRFNHENYGLSITKGKNPKFIVNDELPTCILCGTVTVKTSVKEFTETSAIFEDGTVEENIDSVIFTTGYVFSFPFLEEPLRSLCMKKMFLYKHVFPSNLERASMAIIGLISLKGSILTGTELQARWATRVFKGLCKIPPPQQLMAEVTKKEELIKRGVIKDTSEEKLSYIPYMDDLAACIGTKPNIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTRTVSSDSSKSASLSHYLKVWGAPLLLASVLLICKSSHFLKSVRDKLQNRIFPYLVL
What is the function of this protein?
This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.
What are the official names of this protein?
Dimethylaniline monooxygenase [N-oxide-forming] 4, Dimethylaniline oxidase 4, FMO 1E1, Hepatic flavin-containing monooxygenase 4, FMO 4.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PR1A_SOLLC
Sequence: MKSSIFVACFITFIIFHSSQAQTPRENFLNAHNAARRRVGVGPMTWDDGLAAYAQNYANQRADDCGMIHSDGPYGENLAAAFPQLNAAGAVKMWDDEKQWYDYNSNTCAPGKVCGHYTQVVWRKSVRLGCARVRCNSGWVFITCNYDPPGNYIDNVYGDLEEQKPDFDSKLELPN
What is the function of this protein?
Probably involved in the defense reaction of plants against pathogens.
What are the official names of this protein?
Pathogenesis-related protein 1A1, PR-1A1.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
Protein: CBPYA_COCP7
Sequence: MKALTATLLVGTALAAVPPQQPIQVPTEDSAWAKPLENLKDTFKTLGNDAKQAWNELASAFPDAINEYTLFSAPKKHTRRPDTHWDHIVRGSDVQSIWVEGADGQKRREVDGKLEKYDLRVKAVDPSKLGIDKVKQYSGYLDDKENDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFLELGPASIDKNLKVVHNPYSWNSNASVIFLDQPVNVGFSYSGGSVSDTIAAGKDVYALLTLFFKQFPQYATQDFHIAGESYAGHYIPVFASEILSHKNRNINLQSVLIGNGLTDPLTQYPHYRPMACGEGGYPAVLDESTCRSMDNSLPRCLSMIESCYSSESAWLCVPASIYCNNAMIGPYQRTGQNPYDVRAKCEDGGSLCYSQLGYITEWLNQKSVMDALGVEVSSYDSCNMDINRNFLFHGDWMKPFHRVVPGLIDQIRVLIYAGDADFICNWLGNQAWTDALEWSGREKFAKAELKDLTIVDNENKGKNIGKVKSYGNFTFMRLFGGGHMVPLDQPEASLEFFNRWLGGEW
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: YBEY_RHOPS
Sequence: MPQSNAGGRSDCIGAARDSSFGPMSSSAIPATEVVIAADCWQAEASAESVVLRAIEAAATMIDADTGDAELAVMLTDDDGVRALNASYRGIDKPTNVLSFPAPQPDYQDACQDSGGAPQMLGDIAIAYQTVRREADDEGKPFAHHLSHLAVHGFLHLVGYDHETDAEAETMESTERSILAGLGIPDPYADQDRVS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIGA_ECOLI
Sequence: MIAIADILQAGEKLTAVAPFLAGIQNEEQYTQALELVDHLLLNDPENPLLDLVCAKITAWEESAPEFAEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIGSKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Functions as an mRNA interferase antitoxin; overexpression prevents HigB-mediated cessation of cell growth and inhibition of cell proliferation.
What are the official names of this protein?
Antitoxin HigA.
What is the protein family that this protein belongs to?
Belongs to the HigA antitoxin family.
Protein: BAMD_HAEDU
Sequence: MRKLNSLVSLVLAGLLVIGCSNQNQTEQEILSAQALYTQAQTQLEKGDYASAIASFEKMGSRNVQANLFGEQIQLSLIFAHYKTGEYYKALSLAERFVRAYPNSNNMDYVHYLVGLSNVRLGDNFIQDFFHVNRSSRTIESIRNAYGNFQMIVRIYPQSQYVNDAQQWMVYLLNRMAEHELSIVKFYDKRDASVAVVNRVEEMLRFYPASKSTFDALPYMQKAYQRMGLKDSEAKVAELIEMNKAKVFPKITKPEYSKQF
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamD.
What is the protein family that this protein belongs to?
Belongs to the BamD family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DPEP_SOLTU
Sequence: MAIHTCFSLIPSSFSSPKLPYPKNTTFQSPIPKLSRPTFMFDRKGSFQNGTAAVPAVGEDFPIDYADWLPKRDPNDRRRAGILLHPTSFPGPYGIGDLGPQAFKFLDWLHLAGCSLWQVLPLVPPGKRGNEDGSPYSGQDANCGNTLLISLEELVDDGLLKMEELPEPLPTDRVNYSTISEIKDPLITKAAKRLLSSEGELKDQLENFRRDPNISSWLEDAAYFAAIDNSVNTISWYDWPEPLKNRHLAALEEVYQSEKDFIDIFIAQQFLFQRQWKKVRDYARSKGISIMGDMPIYVGYHSADVWANKKQFLLNRKGFPLIVSGVPPDAFSETGQLWGSPLYDWKAMEKDGFSWWVRRIQRATDLFDEFRIDHFRGFAGFWAVPSEEKIAILGRWKVGPGKPLFDAILQAVGKINIIAEDLGVITEDVVQLRKSIEAPGMAVLQFAFGSDAENPHLPHNHEQNQVVYTGTHDNDTIRGWWDTLPQEEKSNVLKYLSNIEEEEISRGLIEGAVSSVARIAIIPMQDVLGLGSDSRMNIPATQFGNWSWRIPSSTSFDNLDAEAKKLRDILATYGRL
What is the function of this protein?
May act during starch breakdown to convert small oligosaccharides into larger molecules upon which starch phosphorylase can act, or may change the structure of starch molecules and grain architecture by modifying chain length, or may generate from starch and glucose oligosaccharides which can serve either as primers for new starch phosphoenzyme.
What are the official names of this protein?
4-alpha-glucanotransferase, chloroplastic/amyloplastic, Amylomaltase, Disproportionating enzyme, D-enzyme.
What is the protein family that this protein belongs to?
Belongs to the disproportionating enzyme family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast.
Protein: YO19_RHOER
Sequence: MHQPLTADLNPADEVVAVYDRTGNPIGRAPRSVVYSGGLWHASAGVLVRTGDGSRIYVHRRTDTKAVFGGYHDCLAGGVVDPGETPQETAIREVGEELGIFGTADQPLQLTEIARISWDGEWNNSPLRCHLFAFELRYDGPMAHQPSEIAEGWWWTPKELGAHLQDPSWPFVPDSRALLADYCWS
What are the official names of this protein?
Uncharacterized Nudix hydrolase orf19.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: RS21_LEGPH
Sequence: MPTVRVKEGENPEYALRRFKRSCEKAGILTELRRREFYEKPTAERKRKQAAAVKRHLKKISRDVSSRRGVGHRRKKSTT
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DEF_ALKMQ
Sequence: MAIRLIRTDDDPVLRKKSRVVDKIDSRIHTLLDDMIETMYEADGVGLAAPQVGILKQVIVIDVGEGVIELINPEIIKETGSQCDVEGCLSLPGHSGEVERPAIVKVRGLNRQGKMVEIQGTELLARALCHEIDHLNGILFTDKIIKE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: YACG_PHOLL
Sequence: MSELLTIECPTCGKTVVWGEISPYRPFCSKRCQLIDLGQWANEEKRIPSQSENSDSDDWSGQPEQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: MFRB_WOLSU
Sequence: MKFIIDRFDGKKNYEQIYTLAKEDIEAKTLLGVLLLIKQTQDITLNFTASCRMAICGACAVRVNGHSYLACDTKMTELFEEYKNSDTFRISPLGNHRVISDLVVDWEPAIENLRKIKPGLVAKSEFSAKEGCQQNQEEFDRIIKQWDCILCGSCVSECNKFSADQSDYMEPFVFTQAWRLANDSRSKDPMIHVKPAVANGLWNCVHCHECTNRCPKHISAAEDIANLRVMAMKKGLNTGVGPAHAKAFHTDLVEGSGRLNEIRLALRIEGVATVARTGMAITLMRAGKMNPLEIFGGHTIKGHEDLVKMIDAAKAATKE
What is the function of this protein?
Iron-sulfur subunit of 8-methylmenaquinol:fumarate reductase (MFR), that catalyzes the reduction of fumarate using 8-methylmenaquinol-6 as electron donor.  The complex shows no succinate oxidation activity.  Is involved in anaerobic metabolism.
What are the official names of this protein?
8-methylmenaquinol:fumarate reductase iron-sulfur subunit, MFR iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Periplasm. Cell membrane; Peripheral membrane protein; Periplasmic side.
Protein: COAE_PSEF5
Sequence: MTRSVNTPWTLGLTGGIGSGKSAAAQHFIDLGVHVIDADHAARWVVEPGRPALEQIARHFGQGVLQADGQLDRAALRKLIFEVPEQRRWLEALLHPLIAEEIVSHLARAESPYAILVSPLLIESGQSRMTQRILVIDVPQQLQIERTLQRDQISEQQVQAILQAQASREERLRHADDVLVNDRDHAWLRSEVERLHHFYLTLRGGQS
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S30LB_XENLA
Sequence: MNGFSTEEDSRDGPPAQAAPFFGQTCCLIDGGERCPRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNYIQSVRNKRKRKTSDDGGDSPEHETDVPEVDLFQLQVNTLRRYKRYYKLQTRPGLNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNRSRLDQKSESSKQLDA
What is the function of this protein?
Functions as transcription repressor, probably via its interaction with histone deacetylase complexes.  Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus.  Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA.  Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import.
What are the official names of this protein?
Histone deacetylase complex subunit SAP30L-B, Sin3 corepressor complex subunit SAP30L-B, Sin3-associated protein p30-like B.
What is the protein family that this protein belongs to?
Belongs to the SAP30 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: BSDC1_BOVIN
Sequence: MEPGGDGAEDDVGAGIGPPAPGWCLRGRCRVGSQREDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQRDTACTIAATASVVKEKLTTEGSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELAGVSPTSLKEAKVPVARPSTSPEGGPGPQSPCEENLVTPVEPPTEVTPSESSESVSLVTQIAKPPPASEAPALPKDLSQKLLEASLEEQDLAVDTGETGPPPRAQSKPHTPACRPSGPEPRPPARVETLREEILTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWD
What are the official names of this protein?
BSD domain-containing protein 1.
Protein: ADCY4_HUMAN
Sequence: MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLGIVLCALAALLAVAWASGRELTSDPSFLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVALLALGHAFLFTGGVVSAWDQVSYFLFVIFTAYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVLFLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAGAYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGLKMRPSLLMTRYLESWGAAKPFAHLSHGDSPVSTSTPLPEKTLASFSTQWSLDRSRTPRGLDDELDTGDAKFFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFIIQMLVTNRPPALAITYSITFLLFLLILFVCFSEDLMRCVLKGPKMLHWLPALSGLVATRPGLRIALGTATILLVFAMAITSLFFFPTSSDCPFQAPNVSSMISNLSWELPGSLPLISVPYSMHCCTLGFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSECLIVRLYLGPLDSRPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGPPSATLG
What is the function of this protein?
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
What are the official names of this protein?
Adenylate cyclase type 4, ATP pyrophosphate-lyase 4, Adenylate cyclase type IV, Adenylyl cyclase 4.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein: HIS5_BACCZ
Sequence: MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQILKNFKGVVETWKSSQLSI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACL_SHIFL
Sequence: MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQAAHALKGSERSWQRAGHEYTLWMDAEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: PIRT_HUMAN
Sequence: MTMETLPKVLEVDEKSPEAKDLLPSQTASSLCISSRSESVWTTTPRSNWEIYRKPIVIMSVGGAILLFGVVITCLAYTLKLSDKSLSILKMVGPGFLSLGLMMLVCGLVWVPIIKKKQKHRQKSNFLRSLKSFFLTR
What is the function of this protein?
Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin.  Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2).  Binds various phosphoinositide, including phosphatidylinositol 4,5-bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity).
What are the official names of this protein?
Phosphoinositide-interacting protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PROAG_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVCGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MED31_YARLI
Sequence: MAEVATAEKPVTDGIQDGSEQPDRSLRFEAELEFVQSLANPQYLSYLAHNKYLESPEFLNYLSYLEYWREPKYARFLVYPNCLHVLKLLQYATFRKEISRPDFAKQLMDEFYYAWIKPSEAGVFGDDDTLEGLKREDSQAPPGQNVKMENKDGDGDVQMA
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GGE2D_HUMAN
Sequence: MSWRGRSTYRPRPRRYVEPPEMIGPMRPEQFSDEVEPATPEEGEPATQRQDPAAAQEGEDEGASAGQGPKPEADSQEQGHPQTGCECEDGPDGQEMDPPNPEEVKTPEEGEKQSQC
What are the official names of this protein?
G antigen 2D, GAGE-2D, Cancer/testis antigen 4.8, CT4.8, G antigen 8, GAGE-8.
What is the protein family that this protein belongs to?
Belongs to the GAGE family.
Protein: ECM19_YEAST
Sequence: MDWLKNTTIVVLFSHSTDKSNKHKKRQVQCNMRKNTLDMVTIGIACLVGVYTGTRFFEPIVIDRLRKDGNLRTDIPIPEYDEDGNLLKVTPSLSSTPAAPPTPPTPPTPPQQ
What is the function of this protein?
May be involved in cell wall organization and biogenesis.
What are the official names of this protein?
Protein ECM19, Extracellular mutant protein 19.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: NU2C2_GOSHI
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAIAEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GLYCP_NIPAV
Sequence: MPAENKKVRFENTTSDKGKIPSKVIKSYYGTMDIKKINEGLLDSKILSAFNTVIALLGSIVIIVMNIMIIQNYTRSTDNQAVIKDALQGIQQQIKGLADKIGTEIGPKVSLIDTSSTITIPANIGLLGSKISQSTASINENVNEKCKFTLPPLKIHECNISCPNPLPFREYRPQTEGVSNLVGLPNNICLQKTSNQILKPKLISYTLPVVGQSGTCITDPLLAMDEGYFAYSHLERIGSCSRGVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNEFYYVLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEKGRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKPENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIGSPSKIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQSQCPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKDNEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIRPKLFAVKIPEQCT
What is the function of this protein?
Interacts with host ephrinB2/EFNB2 or ephrin B3/EFNB3 to provide virion attachment to target cell.  This attachment induces virion internalization predominantly through clathrin-mediated endocytosis.
What are the official names of this protein?
Glycoprotein G.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.