PharMolix/UniProtQA huggingface dataset:
Protein: RAPA_YERE8
Sequence: MPFTLGQRWISDTESELGLGTVVAIDVRMVTLLFPATGENRLYARNDSPITRVMFNPGDTITHHEGWQLKVEEVSEENGLITYIGTRLDTEETGVSMREVLLDSKLTFSKPQDRLFAGQIDRMDRFALRFRARKYQSEQFRLPWSGLRGIRASLIPHQLHIAYEVGQRHAPRVLLADEVGLGKTIEAGMIIHQQLLSGRAERILIVVPESLQHQWLVEMLRRFNLRFSLFDDSRYSEALLDSTNPFETEQMVICSLDFVRRNKQRLEQLADASWDLLVVDEAHHLAWSEEAPSREYQVIEQLAEHIPGVLLLTATPEQLGQQSHFARLRLLDPDRFHDYEEFINEQQKYRPIADAVTLLLGGERLTDDKLNLLGELINEQDIEPLLKAANSQTEDSEAARQELVTMLMDRHGTSRILFRNTRNGVKGFPHRVLHQIKLPLPTQYQTAIKVSGIMGAKKSLEARAKDMLYPEQIYQEFEGENATWWNFDPRVEWLLNYLIANRNEKVLVICAQAATALQLEQVLREREAIRAAVFHEGLSLIERDRAAAYFASEEDGAQVLLCSEIGSEGRNFQFACQLVMFDLPFNPDLLEQRIGRLDRIGQNREIQIMVPYLENTAQAVLVRWYHEGLDAFEHTCPTGRTIYDSGYQELITYLATPSEQEGLDEFIHTCRQQHEGLKLQLEQGRDRLLEMHSNGGEHGQELAEIIADQDNDVNLVSFALNLFDIVGINQEDRSDNLIVLTPSDHMLVPDFPGLPQDGCTVTFDREQALSREDAQFVSWEHPIIRNGLDLILSGDTGSCAVSLLKNKALPVGTLLAELVYVVEAQAPKHLQLTRFLPPTPVRMLMDKNGTNLAAQVEFESFNRQLNAVNRHTSSKLVNAVQQEVHAMLQQAEALVEEQARLLIEAAKHEADDKLSAELARLEALKAVNPNIRDDEIETLEHNRKMVLENLNQAGWRLDAIRLVVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: VP6_ROTYO
Sequence: MEVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIVTMNGNDFQTGGIGNLPVRNWTFDFGLLGTTLLNLDANYVENARTTIEYFIDFIDNVCMDEIARESQRNGVAPQSEALRKLSGIKFKRINFDNSSEYIENWNLQNRRQRTGFVFHKPNIFPYSASFTLNRSQPMHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANIQQFEHIVQLRRALTTATITLLPDAERFSFPRVINSADGATTWFFNPVILRPNNVEVEFLLNGQIINTYQARFGTIIARNFDTIRLSFQLMRPPNMTPAVNALFPQAQPFQHHATVGLTLRIESAVCESVLADANETLLANVTAVRQEYAIPVGPVFPPGMNWTELITNYSPSREDNLQRVFTVASIRSMLIK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: XPOT_NEOFI
Sequence: MEEQVANAIEIASNPSADPALKTQAFEFVNQLRSDPSGWQVCLSLFTQTPQRSGIVRHVALEVVNSAAQGGLIDLQALAYVKDGLLAYLRQVYGQDAGASDPPNIQNKIAQTITFLFSALYASGWESFFDDLLSLTHKSPSSTTRDNASGIIFYLRVINSIHDEIGDVLVSRSRNEQDKANALKDLIRQRDMQKITSSWQQILSEWRDGNDVIVEMCLKAVGSWVSWIDIGLVVNQTMLDLLFQQLGRAQKEDLRQGEEKVRDAAVDVFTEIIGKKMKPEDKIDMIIFLNLDTIVSQLSNSPPLHGNRFTFKYDTDLAETVAKLVNITVIDIVRALEQEGVSAECKEKANGLLQAFLPHILRYFSDEYDEVCSTVIPCVSDLLTYLRRIAKVNPALASQHSSILLPILKAIIAKMRYDETSSWGEEDEQTDEAEFQELRKRLGILQQMIASVNEQLYMEAVSEMVATTFENLRQSGSQMDWRDLDLALHEMFLFGDLAVKAGSLYTKSNPNNQAAERLIEMMLRMVESDIRSFTHPATQLQYMEICVRYSSFFHHHTHLIPGVLENFLQLVHHPIKKVKTRSWYLFQRLVKQLRQYVGNVAQTVVEALGDLLVIRAELPSEVSEGDEMSSEDHDLADAIFNSQLYLFEAVGIICSTPTVSPDKQVLYAQAVLNPIFLDMEKNLEAAKSQDERAILQIHHDIMALGTLARGFSDWMPGTNTPATLPAPEVSAAFNQVAEATLVALESLKSSFNVRTAARFAFSRLIGVLGSRILPQLPRWIDGLLTQTSSRDEMALFLRLLDQVIFGFKGEIYSILDTLLTPFLQRVFSGIADPTTGTDDEIQLAELKREYLNFLLAVLNNDLGAVIISERNQPIFETVISTIEHFSKDIDDFTTAKMAFSVLSKMSSSWGGPDVIAEASNGAPLAQAPLPGFGQFMITRFSPLCWALPSTPSFNSKDAQAKQVLAEAGGLQRTIYAKTGMEYLTYLRDRELPGMGMGAELIEEFVGALSRLDLKGFRQFFPVCLSNFHHSLDLNMNN
What is the function of this protein?
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.  Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).
What are the official names of this protein?
Exportin-T, Exportin(tRNA), Karyopherin-beta, tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: RHAR_SALA4
Sequence: MANQLILLKKDFFTDEQQAVTVADRYPQDVFAEHTHEFCELVMVWRGNGLHVLNERPYRITRGDLFYIRAEDKHSYTSVNDLVLQNIIYCPERLKLNINWQAMIPGFQGAQWHPHWRLGSMGMNQARQVINQLEHESNGRDPLANEMAELLFGQLVMTLKRHRYATDDLPATSRETLLDKLITALANSLECPFALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRETGMTPSQWRHLSNQSD
What is the function of this protein?
Activates expression of the rhaSR operon in response to L-rhamnose.
What are the official names of this protein?
HTH-type transcriptional activator RhaR, L-rhamnose operon transcriptional activator RhaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK5_XENLA
Sequence: MQKYEKLEKIGEGTYGTVFKAKNRDTHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATMSLVNVVPKLNATGRDLLQNLLKCNPVQRICADEALQHPYFADFCPP
What is the function of this protein?
Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry.  Interacts with D1 and D3-type G1 cyclins.  Regulates several neuronal development and physiological processes including neuronal survival, migration and differentiation, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission, by phosphorylating key proteins.  In the mature central nervous system (CNS), regulates neurotransmitter movements by phosphorylating substrates associated with neurotransmitter release and synapse plasticity; synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis.  May regulate endothelial cell migration and angiogenesis via the modulation of lamellipodia formation.  The complex p35/CDK5 may participate in the regulation of the circadian clock.
What are the official names of this protein?
Cyclin-dependent-like kinase 5, Cell division protein kinase 5, Neuronal cyclin-dependent kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein. Perikaryon. Cell projection, growth cone. Cell projection, lamellipodium. Postsynaptic density.
Protein: PSD_RHIME
Sequence: MSLIDTVRNTLVPVHREGYRFIAIFFVVSLALGFLWEPLMWIGFVLTAWCAYFFRDPERMTPIDDDLVISPADGTVSSVATVMPPEELGLGSEPMLRISVFMNVFNCHVNRAPMGGTVRRIAYRAGKFVNAELDKASQENERNGLVIETKHGQIGVVQIAGLVARRILCWTRESASLEAGERFGLIRFGSRLDVFLPAGAEPRVTVGQTATGGETVLAEFGSAKGPVISRRA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).  Important for establishment of root nodule symbiosis with the host plant.
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NTP1_VAR67
Sequence: MSKSHAAYIDYALRRTTNMPVEMMGTDVVRLKDYQHFVARVFLGLDSMHSLLLFHETGVGKTMTTVYILKHLKDIYTNWAIILLVKKALIEDPWMNTILRYAPEITKDCIFINYDDQNFRNKFFTNIKTINSKSRICVIIDECHNFISKSLIKEDGKIRPTRSVYNFLSKTIALKNHKMICLSATPIVNSVQEFTMLVNLLRPGSLQHQSLFENKRLVNEKELVSKLGGLCSYIVNNEFSIFDDVEGSASFAKKTVLMRYVNMSKKQEEIYQKAKLTEIKTGISSFRILRRMATTFTFDSFPERQNRDPGEYAQEIATLYNDFKRSLRDREFSKSALDTFKKGELLGGDASAADISLFTELKEKSAKFIDVCLGILASHGKCLVFEPFVNQSGIEILLLYFKVFGISNIEFSSRTKDTRIKAVAEFNQESNTNGECIKTCVFSSSGGEGISFFSINDIFILDMTWNEASLRQIVGRAIRLNSHVLTPPERRYVNVHFIMARLSNGMPTVDEDLFEIIQSKSKEFVQLFRVFKHTSLEWIHANEKDFSPIDNESGWKTLVSRAIDLSSKKNITNKLIEGTNIWYSNSNRLMSINRGFKGVDGRVYDVDGNYLHDMPDNPVIKIHDGKLIYIF
What is the function of this protein?
DNA-dependent ATPase that acts as a 5' to 3' translocase on single-stranded DNA and thereby plays a role in transcription termination of viral early genes.  Uses forward translocation in concert with the viral RNA polymerase RAP94/OPG109 subunit and the capping enzyme/VTF to catalyze release of UUUUUNU-containing nascent RNA from the elongation complex.  In addition, acts as a positive elongation factor to assist transcription through problematic sequences.
What are the official names of this protein?
Nucleoside triphosphatase I, NPH-I, Nucleoside triphosphate phosphohydrolase I, NPH I.
What is the protein family that this protein belongs to?
Belongs to the helicase family. NPH I subfamily.
What are the subcellular locations of this protein?
Virion. Note=Virion core enzyme.
Protein: UTS2_PLAFE
Sequence: HPITESAEMPYPGPASLEERGVGSLDDLSLSEQNYPPQRGAGLRYATLEVLLEKQSLLNPFSRVFGIRKQFAGTTECFWKYCV
What is the function of this protein?
Urotensin is found in the teleost caudal neurosecretory system.  It has a suggested role in osmoregulation and as a corticotropin-releasing factor.  The non-hormonal portion of this precursor may be a urotensin binding protein, urophysin.
What are the official names of this protein?
Urotensin-2, Urotensin II, U-II, UII.
What is the protein family that this protein belongs to?
Belongs to the urotensin-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_CELJU
Sequence: MQRPSGRNPQALRPIRITRRYTKHAEGSVLIEFGDTKVICTASVVAGVPSFLRGQGQGWLTAEYGMLPRSTGTRMDREAARGKQQGRTVEIQRLIGRSLRAAIDLNALGENTIHLDCDVIQADGGTRTASITGAWVALADAVAWLKAEGRVTDEPLKRAIASVSVGIYQGVPVLDLDYPEDSAADTDMNVVMGDDGGIIEIQGTAEAEPFTEAEFAAMLSLAKQGIGQLHQLQQQALSH
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: OBG_CORGL
Sequence: MNRFIDRVVLHLAAGDGGNGCVSVHREKFKPLGGPDGGNGGHGGDIILEVTAQVHTLLDFHFHPHVKAERGANGAGDHRNGARGKDLVLEVPPGTVVLNEKGETLADLTSVGMKFIAAAGGNGGLGNAALASKARKAPGFALIGEPGEAHDLILELKSMADVGLVGFPSAGKSSLISVMSAAKPKIGDYPFTTLQPNLGVVNVGHETFTMADVPGLIPGASEGKGLGLDFLRHIERTSVLVHVVDTATMDPGRDPISDIEALEAELAAYQSALDEDTGLGDLSQRPRLVVLNKADVPEAEELAEFLKEDIEKQFGWPVFIISAVARKGLDPLKYKLLEIVQDARKKRPKEKAESVIIKPKAVDHRTKGQFQIKPDPEVQGGFIITGEKPERWILQTDFENDEAVGYLADRLAKLGIEDGLRKAGAHVGANVTIGGISFEWEPMTTAGDDPVLTGRGTDVRLEQTSRISAAERKRASQVRRGLIDELDYGEDQEASRERWEG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_ONYPE
Sequence: MNGFFLVNKPEKMTSHDVVFQIKKKFHFDKVGHTGTLDPLASGLLIICVGKATKLAFLFDKLPKTYQGTFLFNKHYDTLDVTGKLLDTKNTPLTDCNIQKSFASFHQKKYLQIPPMFSAVKIKGKKMYRLARKNQVVDIPPREVFIHHFEKTSLFCRDQVDFLAHVSKGTYIRSLARDLALQLNTYGALLRLQRTAIGTHLLQNAKTIENLELNDLILDSTFFAAYDELILNDYLIKLVKNGTHLDQRQITTKKPFIVKDSNKNFVAYYDTLDENKYYPRYFF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RS19_LEPBP
Sequence: MARSLKKGPFIDDHLMKKITKLNSEGKKTPFKSWSRRSTIYPDMIGHTVMIHNGKAFVPVYVNENMIGHKLGEFAPTRTFKGHGGDKKVAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CASP3_RAT
Sequence: MDNNETSVDSKSINNFETKTIHGSKSMDSGIYLDSSYKMDYPEMGLCIIINNKNFHKSTGMSARNGTDVDAANLRETFMALKYEVRNKNDLTREEIMELMDSVSKEDHSKRSSFVCVILSHGDEGVIFGTNGPVDLKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDDDMACQKIPVEADFLYAYSTAPGYYSWRNSRDGSWFIQSLCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDATFHAKKQIPCIVSMLTKELYFYH
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.  At the onset of apoptosis, it proteolytically cleaves poly(ADP-ribose) polymerase PARP1 at a '216-Asp-|-Gly-217' bond.  Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain.  Cleaves and activates caspase-6, -7 and -9.  Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).  Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes (By similarity).  Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress.  Acts as an inhibitor of type I interferon production during virus-induced apoptosis by mediating cleavage of antiviral proteins CGAS, IRF3 and MAVS, thereby preventing cytokine overproduction.  Also involved in pyroptosis by mediating cleavage and activation of gasdermin-E (GSDME) (By similarity).  Cleaves XRCC4 and phospholipid scramblase proteins XKR4, XKR8 and XKR9, leading to promote phosphatidylserine exposure on apoptotic cell surface (By similarity).
What are the official names of this protein?
Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, IRP, LICE, Protein Yama, SREBP cleavage activity 1, SCA-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_COLP3
Sequence: MWIGVISLFPEMFNAITEYGVTGRAIRNGLIDFHLWNPRDFTHDKHRTVDDRPYGGGPGMLMMVQPLRDAIAAARKAAEVNGGKAKVIYLSPQGRKLDQQGVSELAQHDRLVFIAGRYEGIDERLIASDIDEEWSVGDYILSGGELPAMNVIDAVARLVPGVLGHKESAEQDSFSNGLLDCPHYTRPEVLTTPQGDEMSVPKVLLSGNHEHIRLWRQEQSLLRTWTRRPELLNNLALTAEQEKALTLIKKQVK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPP_SALHS
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILDRVETIRKLSKSSRAGNEANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPDLNDATIKKAVESLSLELVLTAHPTEITRRTLIHKMGEINNCLKQLDNTDIADYERHQVMRRLRQLIAQSWHTDEIRKQRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVDFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIHVLVSELSMVDATPELLALVGEEGASEPYRYLMKKLRARLMATQSWLEARLKGEKLPKPAGLLTQNEQLWEPLYACYQSLQACGMGIIANGELLDTLRRVKCFGVPLVRIDIRQESTRHTEALGEITRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWEPSNDTREVLETCKVIAEAPKGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNADDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEVTVSSLSLYTSAILEANLLPPPEPKDSWRHIMDELSVISCETYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFSKADLWLADYYDQRLVAKTLWPLGKELRDLLEEDIKVVLAIANDSHLMADLPWIAESIQLRNVYTDPLNVLQAELLYRSRLTEEQGKSPDPRVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: YCIB_ECO24
Sequence: MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRFRKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQRMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLIFTLLSGIYIYRHMPQEDKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCAB2_BOVIN
Sequence: MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASSADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
What is the function of this protein?
Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (By similarity).  Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity).  Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity).  Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore (By similarity).  Promotes KCNA4 channel closure (By similarity).  Modulates the functional properties of KCNA5 (By similarity).  Enhances KCNB2 channel activity (By similarity).  Binds NADPH and has NADPH-dependent aldoketoreductase activity (By similarity).  Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) (By similarity).
What are the official names of this protein?
Voltage-gated potassium channel subunit beta-2, K(+) channel subunit beta-2, Kv-beta-2.
What is the protein family that this protein belongs to?
Belongs to the shaker potassium channel beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Synapse, synaptosome. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasmic side of the cell membrane via its interaction with pore-forming potassium channel alpha subunits. Associates with microtubules when unphosphorylated.
Protein: ATPL_BIFLO
Sequence: MDIITLAEVAGNLSVIGYGIGTLGPGIGLGILFGKAMESTARQPEMSGKIQTIMFIGLALVEVLALIGFVAALII
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSP70_ALTAL
Sequence: KTNKIVITNDKGRLSKEEIERMLAEAEKYKAEDEAEAARISAKNALESYAYSLRNTLSDSKVDEKLDAGDKQKLTAEIDKTVQWLDDNQTATKDEYESQQKELEGVANPIMMKFYGAGGEGGMPGGMPGGGMPGGAPGGAAGDDGPTVEEVD
What are the official names of this protein?
Heat shock 70 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NU2C_CROS5
Sequence: MDFSSNIASQLNAGTILPEGIVIITLMVVLIGDLIGGRNARMWLPYGAIAGLLAALFALYTAWDNPSTIGFLGAFNGDNLSIVFRGIIALSTIVTLLMSIRYVEQTGTSLAEFIGIMLTATLGGMFLSGANELVMIFISLEMLSISSYLMTGYMKRDPRSNEAALKYLLIGASSSAIFLYGSSLLYGLSGGETTLDTISAKILASDGSSSLGLAIALVFVIAGIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFSSIVDEWHLIFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLTAGTDAGYSSMVFYLLVYLFMNLGAFSGVILFSLRTGTDQISEYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAELYGLVLLALVTSVVSIYYYIRVVKMMVVKEPHEMSDSVKNYPEIRWNLEGMRPLQVGLVLSVIATSLAGILSNPLFSLANDSVTSTPILQSTIVNTRISQGEIPSSTIDP
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MEX1_JACME
Sequence: YPESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDCEYRSHGCDGGYQTPSLQYVVDNGVHTEREYPYEKKQGRCRAKDKKGPKVYITGYKYVPANDEISLIQAIANQPVSVVTDSRGRGFQFYKGGIYEGPCGTNTDHAVTAVGYGKTYLLLKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFPIKGYR
What is the function of this protein?
Cysteine protease.
What are the official names of this protein?
Mexicain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Secreted.