PharMolix/UniProtQA huggingface dataset:
Protein: CY550_APHFL
Sequence: LELDETIRTVPLNDKGGTVVLSLEQVKEGKLFNYACAQCHAGGVTKTNQNVGLEPEALAGALPNRMKNPTTYDGEEEISEIPSIKSANIFRNLTDEDLKAIAEHILLEPLVVGTKWGGK
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550, Low-potential cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: Y469_THESQ
Sequence: MSGHNKWANIKHRKMAQDAKKSKIFTKLIREIIVAAREGGGNIETNPRLRAAVERARAENMPKENIERAIKRGTGELEGVDYQEVIYEGYAPGGVAVYIRALTDNKNRTAQELRHLFNKYGGSLAESGSVSWIFERKGVIEISRDKVKDLEELMMIAIDAGAEDIKDTEDPIQIITAPENLSEVKSKLEEAGYEVEAKVTFIPKNTVKVTGKDAEKVLEFLNALEDMDDVQEVYSNFEMDDKEMEEILSRLEG
What are the official names of this protein?
Probable transcriptional regulatory protein TRQ2_0469.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRQ_ECOL5
Sequence: MRLTAKQVIWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLAALLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQSMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLMYAGLAVLLLALRYKKLLSLFNRLRKQAHNKLSL
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENGB_BURPS
Sequence: MAFLLHQARFFTTVNHLRDLPPTVQPEVAFAGRSNAGKSTAINVLCNQKRLAFASKTPGRTQHINYFSVGPAAEPVAHLVDLPGYGYAEVPGAAKAHWEQLLSSYLQTRPQLCGMILMMDARRPLTELDRRMIEWFAPTGKPIHSLLTKCDKLTRQESINALRATQKSLDAYRDAGYAGKLTVQLFSALKRTGLDDAHALIESWVRPAAADEDRAAVAE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RLMH_RHILW
Sequence: MRIGLFAVGRLKSGPEKDLAARYFDRFAKAGPAVGLELARVAEVAESRASNAETRKREEAAMLLKSLADGSILILLDERGKALDSEAFASLLGSYRDQGKRDLTIAIGGADGLDPSLYDRADATLCLGKMTWPHQLVRILIAEQLYRAVTILSGHPYHRV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THAP5_BOVIN
Sequence: MPRYCAAICCKNRRGRNNKERKLSFYPFPLHDKERLEKWLKNMKRDSWVPSKYQFLCSDHFTPDSLDIRWGIRYLKQTAIPTIFALPEDNQEKDPSKKKSQKKKLKSEKEVCLKAKSEESFASNEPKKHPVNTDLLPEHAELLESSALVKPPDPKAESVQNNILTLSLVKQGTRKPESILETSVNQDMGIGGFHTSFENLSSTTITLTTASSEGIQQPLETQEVIEITTNHLANPHFTNNSVEIKSAQENPFILSTVTQTVEELNTDKESVIAIFVPTENSKPAINSFIPAPKTVEMEEDIDIEDSYKDVDYETEVLQIEHSYCRQDVNKEHLWQKVSKLHSKITLLELQEQQTLGRLKSLEALIRQLKQENWLSEENVKIIENHFTTYEVTMI
What is the function of this protein?
Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro).  May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase.
What are the official names of this protein?
THAP domain-containing protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCED_STAAR
Sequence: MKKTLLASSLAVGLGIVAGNAGHEAQASEADLNKASLAQMAQSNDQTLNQKPIEAGAYNYTFDYEGFTYHFESDGTHFAWNYHATGANGADMSAQAPATNNVAPSADQSNQVQSQEVEAPQNAQTQQPQASTSNNSQVTATPTESKASEGSSVNVNDHLKQIAQRESGGNIHAVNPTSGAAGKYQFLQSTWDSVAPAKYKGVSPANAPESVQDAAAVKLYNTGGAGHWVTA
What is the function of this protein?
Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells.
What are the official names of this protein?
Probable transglycosylase SceD.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. SceD subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VRAB_STAAS
Sequence: MNQAVIVAAKRTAFGKYGGTLKHLEPEQLLKPLFQHFKEKYLEVISKIDDVVLGNVVGNGGNIARKALLEAGLKDSIPGVTIDRQCGSGLESVQYACRMIQAGAGKVYIAGGVESTSRAPWKIKRPHSVYETALPEFYERASFAPEMSDPSMIQGAENVAKMYDVSRELQDEFAYRSHQLTAENVKNGNISQEILPITVKGEIFNTDESLKSHIPKDNFGRFKPVIKGGTVTAANSCMKNDGAVLLLIMEKDMAYELGFEHGLLFKDGVTVGVDSNFPGIGPVPAISNLLKRNQLTIENIEVIEINEAFSAQVVACQQALNISNTQLNIWGGALASGHPYGASGAQLVTRLFYMFDKETMIASMGIGGGLGNAALFTRF
What are the official names of this protein?
Putative acetyl-CoA C-acetyltransferase VraB.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: DCDA_MYCLE
Sequence: MNVHTAGPRHAEKTRHTATPQRVQPSDDLLRLASNVWPRNITRDETGVACIAGNKLTDLAGEYGTPLFVIDEDDFRFRCREIAAAFGGGENVHYAAKAFLCTEIARWIDEEGLSLDVCSGGELAVALHASFPPERISLHGNNKSVAELKDAVKAGVGYIVLDSTTEIERLDAIAGEAGIVQDVLVRLTVGVEAHTHEFIATAHEDQKFGLSVASGAAMAAVRRVFATDNLRLVGLHSHIGSQIFDVAGFELAAHRVIGLLCDIVGEFDPEKTAQLSIVDLGGGLGISYLPDDDPPPIFELAAKLGAIVSNESAAVGLPVPKLMVEPGRAIAGPGTITLYEVGTIKDVDVSATAHRRYVSIDGGMSDNIRTALYDAQYDVRLVSRTSDAPAAPASIVGKHCESGDIVVRDTWVPDDLKPGDLVGVAATGAYCYSLSSRYNMLGRPAVVAVCAGQARLILRRETVDDLLSLEVR
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: QUEC_VEREI
Sequence: MRAGHALVLFSGGQDSTTCLAWALTQFAHVETIGFDYGQRHHVELQARQTVLAAIRSRFAQWRERLGADHMIDLSVLGRISDTALTRDSAIQLSAAGLPNTFVPGRNLLFFNLAAAVGYRRGLHTLVGGMCETDFSGYPDCRDDSLKALQVAVSLGLGQRFTFETPLMWLDKAATWELARSLGGQALVELIVRDSHTCYHGVRGVLHAWGHGCGTCPACVLRQTGYDRWQARPVAAP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: HYAL_LYTVA
Sequence: NVEIGTPSTTVTWTVPTAIDASAVTTVSSHNPGQSFITGTTTTVVYTATDEFGNIGQCAFTITVTATDSIDPVVTVSSGFITQQVEIGLGGVNVFYTEPTATDNSGTAVLFSRSAQPGDFFPVGQTVVTYIFQDPSGNFGTGTFTVNVVEVDTTPPVVTVPNGIITRQVEIGTSGIIVFFSEPTATDNSGTAILDSRTHQPGDVFPVGQTIVTYTFRDPAGNPATGTFTINVVEVDTTPPVITVPTPSIITRQVEVGTPGVSVFYQEPTATDNSGTAILVSRTNQPGDVFPVGQTVVTYTFQDPSGNPASATVTINVVEVDTTPPVISVPSTFITRTVELGTPGVNVFYPEPTASDNSGTAILVTRTNQPGDFFSVGQTVVTYTFQDPTGNPATATVTINIVEEDTTPPTVNCINDVIRTVELGTTSAQVFYSEPTASDVGQATLISRTAQPGDSFPVGATVVTYIFGDNAGNIADPCVFTITVNTVDTTPPTVNCVSDVVRVVELGTTSLAVVYTEPTATDISGTASLV
What is the function of this protein?
Major constituent of the hyaline layer.  The hyaline layer of echinoderm embryos is an extraembryonic matrix that functions as a substrate for cell adhesion through early development.
What are the official names of this protein?
Hyalin.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RK14_OLIPU
Sequence: MIQPQTYLNVADNSGARELMCIRIIGASNRRYAHIGDVIVAVIKEAIPNTPLERSEVIRAVIVRTCKELKRNNGTIIRYDDNAAVVIDQEGNPKGTRVFGAIPRELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SHO1_NEUCR
Sequence: MQSYGGSVNYPPSFNNPKMEHGRNSYRRKGIDMGNIIGDPFALATTSIATLSWIIILFGSIFGFRDQNDGSNGAPVIVWPTYSWFTLVFNFFLILGIFIVIASDSAQTYHVAIVGYLAVGLVGSTSSINNLIYSGVASMEATAAGYILLSMVTIIWIFYFGSAPSAVPRAYIDSFALTKESTLPAHHMSRQTMNHNGLSSPNAYGSYNMRPETSASGLQPPQMYTGQLNGLENPARQSQIPQGFSSNNIPKPQGEGEIVPPTEYPYRAKAIFSYEANPDDANEISFSKHEVLEISDVSGRWWQARKENGETGIAPSNYLILL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein sho1, Osmosensor sho1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NAPA_HISS2
Sequence: MNLSRRDFMKANAALAAASVAGLIIPVKNVNAADTSITWDKAVCRFCGTGCAVLVGTKDGRVVASQGDPDAEVNRGLNCIKGYFLPKIMYGKDRLTHPMLRMKNGQYDKEGEFTPVTWDFAFKTMAEKFKSALKAKGPNGVGMFTSGQSTIFEGVAKSKLFKAGLLSNNIDPNARHCMASAAVAFVRTFGIDEPMGCYDDIEHADAFVLWGSNMAEMHPILWSRISDRRLANPDTVSVNVLSTFEHRSFELADLGILLKPQSDLAILNYIANYLIENNAINREFIEKHTKFKRGETDIGYGLRPQDPREQTAKNVKTAGKMYDSSFEEFKKLVAPYTLEKAHEISGVPKEQLEKLAKLYADPNKKVVSYWTMGINQHTRGVWANHLIYNIHLLTGKISLPGCGPFSLTGQPSACGTAREVGTFIHRLPADLVVIKPEHRKIAEKIWKLPEGLISDKLGFHAVAQSRALKDGKMQVLWQMCNNNMQAGPNINEETYPGWRNPDNFIVVSDPYPTVSALSADLILPTAMWVEKEGAYGNAERRTQFWRQQVKAPGEAKSDLWQLVEFSKYFTTDEVWPAEILAKNPAYQGKTLYEVLYLNGQVNQYSNDELKGRLNDEAYHFGFYIQKGLFEEYASFGRGHGHDLADFDTYHKARGLRWPVVDGKETLWRYREGYDPYVKAGEGVSFYGQADKRAVILAVPYEPPAEVPDRKYDLWLTTGRILEHWHTGSMTRRVPELHRSFPNNLVWMNPNDAKKRGLKHGDKIKVISRRGEITSYIDTRGRNKCPEGLIYTTFFDAGQLANKLILDATDPISKETDFKKCAVKVVKA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ARGC_ROSDO
Sequence: MTYSIAILGASGYTGAELIRLIAGHSALKITALGAFSKAGQSVAQVFPHLRHLDLPALLQIDQIDFANIDLCFCALPHKTSQEVIAALPSDLKVVDLSADFRLRDPDAYEKWYGNKHAALKQQAEAVYGLTEFYRDDIKTARLVAGTGCNAATGQYMLRPLITAGVIDLDDIILDLKCAVSGAGRSLKENLLHAELSEGYHAYATGSTHRHLGEFDQEFSKLAGRPVQIQFTPHLIPANRGILGTGYLRGEAAQIHDTLSQAYANEPFIDVLPFGETPSTRHVRGSNFCHIGVVADRQPGRALVVAALDNLTKGSSGQALQNANLMLNIKETEGLMMPPLFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFGM_DROPS
Sequence: MSLITRVLQGNLTRKNALQTLTRCGYSSHAKFAEHRPIEKIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTMWKDTNVNIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGLVDLVREQAIYFEGENGMDVRLDEIPQDMRVESQERRQELIEHLSNADETFGEFFLEEKPFSEADLRAALRRTCINRTFTPVLVGTALKNKGVQPLLDAVIDYLPNPGEVENLGFIEREGKDPEKIVLNPARDGKDPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSSQMEDVNEVYAGDIFALFGVDCASGDTFTTNPKNNLAMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGVMEPLPPNQNTLLEFVDETVGTNVPKQFVPGVEKGYREMAERGMLSGHRLSGIKFRLQDGGHHIVDSSELAFMLAAHGAIKEVFQNGSWQILEPIMMVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQYQETQGASQPDKKKKKN
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.  Essential during development as it acts as a retrograde signal from mitochondria to the nucleus to slow down cell proliferation if mitochondrial energy output is low (By similarity).
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HIS6_ALKCK
Sequence: MLAKRIIPCLDVKEGRVVKGTQFLSLRDAGDPVELAAFYDKEGADELVFLDISASHEGRETMVDVVREVAATLAIPFTVGGGINTLADIRRILRAGADKVSINTAALLRPAFIREGADYFGSQCIVVAIDAKFDQALGTWRVYTHGGRKQTNWLATDWAKEAVRLGAGELLVTSMDQDGAKTGFDLPLLKAINEVATVPVIASGGAGAANDFVDVFKYNYADAALAASIFHYKETSIQEVKARLREEGECIR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_CAMFF
Sequence: MIIYDSILKQKVEFKPIREYEANIYVCGPTVYDDAHLGHAKSSISFDLLRRTLKSLGYKVKFIKNFTDIDDKILKKMSQTGKSLEDITNHYISRYKADMYALNVADADIEPKATTSLTSIINYITTLFENGWAYKIDDGIYFDTSKDDKYLSLSGRKDENLIARVASKDEKKDEKDFVLWKFDENWYDSPFGRGRPGWHSECVAMIKDHFCGSCEFEIDIHAGGADLLFPHHENEAAQCRCAYNKNLAKYWMHNGFVQVNNEKMSKSLGNSFFIKDALELVPGEALRFYLMSSHYRANFNYDIDDLKSSKKRLDKIYRLKKRLIGVKTSKTDAKFKKDILDAMSDDLNISVALAILDEMVNNANAKLDNEPKNRDFKQILVSNLEFVKELLGILYIDEFKWFQWGVDDSLKQEISVLIDQRNMAKKDKNFILADQIRDKLTNMDISIMDTPNGTMWEKV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_ECOL6
Sequence: MTAPSQVLKIRCPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RL20_GEOKA
Sequence: MPRVKGGPVTRRRRKKVLKLAKGYFGAKHALYRVANQQVMKSLMYAYRDRRQRKRDFRKLWIVRINAAARQNGLSYSRLMHGLKLAGVEVNRKMLADLAVNDQAAFAQLADLAKANLNK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: FNO_METTM
Sequence: MKIAVLGGTGDQGLGLALRLALAGEEVIIGSRDAEKAVSAAQKVLEIAERDDLKVKGATNAEAAEEAEVAILTVPLQAQMATLGSVKEAIKGKVLIDATVPIDSCLGGSAVRYIDLWDGSAAERAARFLEDQGTRVAAAFNNISASALLDITGPVDCDCLIASDHRDALDLASELAEKIDGVRAIDCGGLENARVIEKITPLLINLNIKNRIRNAGIRITNLPE
What is the function of this protein?
Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i. e.  the reduction of F420 with NADPH.  Probably functions in the regeneration of NADPH required in biosynthetic reactions.
What are the official names of this protein?
F420-dependent NADP reductase, F420H2:NADP oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the F420-dependent NADP reductase family.
Protein: VAC8_ASHGO
Sequence: MGGCCSCLKESQDDATVLPIAENEREAVTSLLGYLEDKDNYDFYSGGPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRPVDREVLEPILILLQSHDPQIQIAACAALGNLAVNNENKILIVEMGGLEPLIEQMKSNNVEVQCNAVGCITNLATQDDNKAKIAHSGALVPLTKLAKSKNIRVQRNATGALLNMTHSGENRKELVDAGAVPVLVSLLSSSDADVQYYCTTALSNIAVDESNRRKLSQTEPRLVSKLVVLTDSPSARVKCQATLALRNLASDTGYQLEIVRAGGLSHLVKLIQCNSMPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVKLLDYNDNEEIQCHAVSTLRNLAASSEKNRQEFFESGAVEKCKQLALVSPISVQSEISACFAILALADNSKLELLDANILEALIPMTFSTNQEVAGNAAAALANLCSRINNYEKIIESWTEPSKGVCGFLIRFLQSEYPTFEHIALWTILQLLESHNETMLGLIKSNKEIVKSIKRLSDINYENAQKASSLHSRLQQVNGGSVASGSEQYEHASLELYNITQQIMQFLN
What is the function of this protein?
Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
What are the official names of this protein?
Vacuolar protein 8.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Vacuole membrane; Lipid-anchor.
Protein: Y4636_DICDI
Sequence: MDIFDSTITSFEDFPSERFKEQLESLTYESIERASQFVLENLPCIDDLFDVLLNRMRKSAYHKRLLFFNLIDCICIGCSRIENDVYKKFIINNVDEIIPLILPDDNLEVKKKNRETIERIIRSWSNNHVFNDTFISRAFSILSGVAKESRSICPNLSEKEIARLLKRMEEKRKDQNKKRLDLEDSHPLDEFLELWFNFNLDNSSSSSSSSSSSSSSSSTTTTTTTTSELSSISTSLNSIRTNSSCSNNNLQIDIEIIEKEKEKQKEHFNSFNDTSITTPSTSSSTTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSLDNSTTNDNNNNTSNNKNNNNDNYNNQSILEKERIYKLDYEVYDSFKSQFTIPEWPSYEIEDIDLFTSGNDGEYQDYIENEYNSFDQNSYLEYKKKYKNNEFENSIGNSNNYYNRNSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEDSGNFMNSILNYCFYEHKNHFNFIKNNRNNHYPYNTSGYLNNRVDNYQPYSPKTTSDSHKLQEYFNKIDYMNKNGISVVDICAKSKSFEIPNICGADGGDSDRMDIDTNNSLKNENKQNDSHRGKSRKRRSSSRGESEHSRYYRDSSRDAKDRDSRDHRDNRDHRDSRDHRDRRDSRDHRDSRDYRDHRDSRDYRDSRDSRDSRDSRDRESRDSRDHRESRDSRDHRESRDSREYRESRDHRDHSRDSRDQYRDKDHRDSSDGRDHRNRDDKYQIDKRDNQHHNERNDSRNDRNDKNDKNDKNDKNDKNQEKYSERYHNERDSRDNEKDFYRSKETMVNNDNRSSSNRSSNRH
What are the official names of this protein?
Putative uncharacterized protein DDB_G0281733.
Protein: Y1062_YERPY
Sequence: MYDNLKSLGITQPEDVDRYSLRQEANNDILKIYFRKDKGEFFAKSVKFKYPRQRKTVVSDNASHGYKEINEINPNLRYVIDELDQLCKRDQIEVDLKRKILDDLRHLESVVTNKIAEIEADLEKLTNGR
What are the official names of this protein?
UPF0325 protein YPK_1062.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: YCIB_SHIFL
Sequence: MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRFRKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQRMLSKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLIFTLLSGIYIYRHMPQEDKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis (By similarity).  Essential for normal cell division (PubMed:8830250).  Involved in virulence through intercellular spreading (PubMed:8830250, PubMed:9746567).
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANC_AGRVS
Sequence: MEIINTIAALRHRLDACRKAGKSIGFVPTMGYLHKGHLTLVEQAKAENAVTVASIFVNPLQFGKGEDLEKYPRDLERDSEMLEAAGVDFLFAPGVADMYPRPMETVVDLPGLGGELEGKARPGHFAGVATVVTKLFNIVQPDAAYFGEKDYQQVAIIRRMVDDLAMPVRVVPVATVREADGLACSSRNVYLTEEQRAAATIVPKALDEAERLYKAGMRDTAEMEAALAAFIAREPQAKPDVVAVRHPDTLATLPHLDQPFLVLLYVQIGTTKLLDNRVITIKSKKEAAE
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPB_SALTI
Sequence: MTEAMKITLSTQPADARWGDKATYSINNDGITLHLNGKDDLGLIQRAARKIDGLGIKQVALTGEGWDTERCWAFWAGYKGPKGVRTVMWPDLDDAQRQELDNRLTIIDWVRDTINAPAEELGPEQLAQRAVDLLCSVACDSVTYRITKGEDLREQNYMGLHTVGRGSERPPVLLALDYNPTGDKDAPVYACLVGKGITFDSGGYSIKQSAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIIRYRNGKNVEVMNTDAEGRLVLADGLIDASAQHPRLIIDMATLTGAAKTALGNDYHALFSFDDTLAGRLLTSAAQENEPFWRLPLAEFHRNQLPSNFAELNNTGSATYPAGASTAAGFLSHFVENYREGWLHIDCSATYRKAPVEQWAAGATGLGVRTIANLLTA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_ECOLU
Sequence: MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHQS_METM6
Sequence: MKFGWIKTTGTDSEERMDSVKDALESSIPGIIAEKDEISSVRELGNIKIVSDSLDADVVLINKGEDLEILKSAKLSGKETAVYVVINTKDDEVYATEVSKLDFVDYIVLEGSDWTIIPLENIIADLFGEEIKIVSVVTSVKDAEAAYEILEKGVDGVVLIPNDINEVKDFSKLIERMNSESVKLDYATVTKIEPVGSGDRVCIDTCSMMEMGEGMLIGSYSRGMFLVHSETVENPYVATRPFRVNAGPVHAYILCPENKTKYLSDLKAGDKVLVVNKNGETRESIIGRVKIEKRPLFLVEAEYNGENLRTILQNAETIRLVGEDGKPVSVVDLKVGTKVLIKPDENARHFGMAIKETIIEK
What is the function of this protein?
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
What are the official names of this protein?
3-dehydroquinate synthase, DHQ synthase, 3-dehydroquinate synthase II.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.