PharMolix/UniProtQA huggingface dataset:
Protein: PPNP_ECO24
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: REEP6_MOUSE
Sequence: MDGLRQRFERFLEQKNVATEALGALEARTGVEKRYLAAGALALLGLYLLFGYGASLLCNVIGFVYPAYASVKAIESPSKEDDTVWLTYWVVYALFGLVEFFSDLLLFWFPFYYAGKCAFLLFCMTPGPWNGALLLYHRVIRPLFLKHHMALDSAASQLSGRALDLAAGITRDVLQALARGRALVTPASTSEPPAALELDPK
What is the function of this protein?
Required for correct function and survival of retinal photoreceptors (PubMed:24098485, PubMed:24691551, PubMed:28475715).  Required for retinal development (PubMed:28369466).  In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (PubMed:28475715).  May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (PubMed:24098485, PubMed:28369466).
What are the official names of this protein?
Receptor expression-enhancing protein 6, Polyposis locus protein 1-like 1, TB2 protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein.
Protein: RSMA_PSYA2
Sequence: MSKISFDAQSISNSLRAAKHQPRKRFGQNFLHDRSVIREIVESIRLERDDNLIEIGPGMGALTEPLLAEVDAMTVVELDRDLADSLRIRIGANSHPNFTIIKDNAMHVDYRELYSEERGKLRVVGNLPYNISTPILFHLLSYADVIEDMHFMLQKEVVERITADVGSKTYGRLSVIMQYHCHTDYLLTVPRGAFNPPPKVTSAVFRLTPHIIKPVVAEDEEYFALVVRETFNHRRKTLRAIFKKSTLLPTLSEDDFAACAIDPQARPETLNVKDFVNLSNQARTIPV
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_GRABC
Sequence: MDRIRIRGGHPLAGEIAIGGAKNAALPVMACGLLTDDRLVLNNVPRLADIGTMKALIEQHGIAVERLDPLGRILSLGGQITNTEAPYDIVRKMRASVLVLGPLLARCGEARVSLPGGCAIGTRPVDMHLKGLEQMGAVITLESGYIDARVQGRLRGADIVLPMPSVGATENLLMAASLADGITTLRNAAREPEIEDLAHCLISMGAKIEGIGTGELRIEGVKHLHGAEHSIIPDRIETGSYACAAAITGGRLLLRNARLDHLGAVARTLREAGVEIEEQDSGLLVSRRNGLHGVDVMTEPYPGFPTDMQAQYMVLMSVAEGASMVTETIFENRFMHVPELNRMGARINVHGASAIVRGVSQLSGAPVMATDLRASLSLILAGLAAEGETIVNRVYHLDRGYESVAEKLSACGADIERISG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_BACTN
Sequence: MKNEPIYNLLNSINSPDDLRRLEVDQLPEVCDELRQDIIKELSCNPGHFAASLGTVELTVALHYVYNTPYDRIVWDVGHQAYGHKILTGRREAFSTNRKLGGIRPFPSPEESEYDTFTCGHASNSISAALGMAVAAAKKGDDQRHVIAIIGDGSMSGGLAFEGLNNSSTTPNNLLIILNDNDMAIDRSVGGMKQYLFNLTTSNRYNQLRFKASRLLFKLGILNDERRKALIRFGNSLKSMAAQQQNIFEGMNIRYFGPIDGHDIKNLSRVLRDIKDLKGPKILHLHTIKGKGFAPAEKHATEWHAPGKFDPVTGERFVANTEGMPPLFQDVFGNTLVELAEANPRIVGVTPAMPSGCSMNILMSKMPKRAFDVGIAEGHAVTFSGGMAKDGLQPFCNIYSSFMQRAYDNIIHDVAIQNLPVVLCLDRAGLVGEDGPTHHGAFDMAYLRPIPNLTIASPMNEHELRRLMYTAQLPDKGPFVLRYPRGRGVLVDWKCPLEEIPVGKGRKLKDGKDIAVISIGPIGNKARSAIARAESESGRSIAHYDLRFLKPLDEELLHEVGRTFRHIVTIEDGTIQGGMGSAVLEFMADHEYTPTVKRIGIPDKFVQHGTVAELYQLCGMDEDSLTKELLKQCELLPDMSKIKELTN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PROA_SYMTH
Sequence: MDVRSMARQARAAQRQLELTSPEERNAALEAIARALEARAGQIVAANRADLAAAEEAGLPGPMIARLRLDEGKLAGVIRGVRAVAELPDPLAVEPQAWIRPNGLRIQRVRVPLGVVGIIYESRPGVTVDAAVLCLKAGNAVLLKGGKEAARSNAALGEAMAAGLQEVGLPVELAQVLPSTREAAQELMAARSLVDVLIPRGGAGLIRATVEQSQVPVIETGTGVCHVYVHRAADLAMAREIVLNAKCSNPAVCNAAETLLVDREVAAPFLAEAGPALLAAGVRLRACPEALAILQETARPDLAGAGPAAVEPATEEDWAAEYLDLCLAVKVVSGLDEALAHIARYGTGHSEAIVTGDAGAADRFLRSVDAAAVYHNASTRFTDGGEFGFGAEIGISTQKLHARGPMGLAELTTYKYVVLGNGQVR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_SYNPW
Sequence: MPTSLLRVGVVFGGASGEHAVSIRSARTVIEAFSAPENQERFAVIPHYIDREGRWWGPAVAERALEQNKALDAHELPQPLPAPGLRHWPVDPDSVDLWYPVLHGPNGEDGTVQGLFTLMNKPFVGSGVLGSAVGMDKLAMKAAFAAAGLSQVPYMGLTAADLEDPERLEQLLTRVEQELGYPCFVKPANLGSSVGITKANNRDELLAGLHQAAALDPRLLVEQGVNARELECAVLGRRHLRASVVGEIRFDADWYDYETKYTEGRSHTLIPAPLPALVSQQIQAMAIRACHAVHAFGQARVDVFYDETSGEIWLNEINTLPGFTSQSMYPTLWAASGIPLPQLVAELVDTAQE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP18_YARLI
Sequence: MAFGIRRAYPTPIVKPLWPYAVGGVITFFLFAKAANASMNTEEFINDPRNPRFKAGGVKEEH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169).  F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333).  Part of the complex F(0) domain (PubMed:27373333).  Minor subunit located with subunit a/ATP6 in the membrane (PubMed:27373333).
What are the official names of this protein?
ATP synthase subunit J, mitochondrial, ATPase synthase I subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase j subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.
Protein: GSA_ECOK1
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVEPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEGLREAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYP2_EMENI
Sequence: MMQWTSLVQKAQSFIDPANFTIPNLTSSSDRNPSKSSLFRQQFRLPDSQNPLQEITAELILPVSHTSSSASGAQSKNIDRGGNRYAGRLHLSERFLCFSTQPTSFLPSATLATSTYWAGQTNGTGPSGNGFTIPLCSIRRVERLNSQSHIFSLALTTWNGALGKQQAPGFTPQRFTIELVGSRQACERFCDGLKKNLRESMKEIENLRLVVNDCYSEYLLSGAKSKAQSADDPEARPPPDAGLGMLFRYPGDARKLRDRSKMRLWGEYFRENGRNATLIRQPTFHKLIRVGLPNRLRGEIWEVASGSLNLRLRSPKLYEQTLAKFEGQESLAIDEIEKDLNRSLPEYAGFQSEEGIGRLRRVLTAYSWTNAEIGYCQAMNIVVAALLIYMSEAQAFFLLSVLCDRLVPGYYSTTMYGTLLDQKVFESLVEKTMPILWDHLNKSDVQLSVVSLPWFLSLYINSMPLVFAFRVLDVFFLEGPKVLFQVGLAILRINGEELLDVQDDGSFISVLKSYFSRLDESAHPRSENPKLRAITRFQELMVVAFKEFSQITHQTITEQREKHKDAVLENIESFAKRTSIRNLGPESKKLSSDDLGAIYDRYYEVLYDYQQRQKVIEEEKKRQERKKSQRVSVIGPSVDREVGRVGLGPSPTHMDYNAFREFLAATAKWAIADSPGPSRKQSDSGSFRGLGRPTMNKRPSPADHEFMQRLFRKWSTDPDDGLSLQDVVNGIARLKGPRDIMNNITYFFDLYDDNGDGKVDREGILRMSEALLFLSRRGFDGTITPSQSTENLMPGKEEDKLSTGERFLGSVSSFIRRCFEYADPTKKTLEAEKLAETTDNLNSFSIGDDEEDLIDVGDDEVKSESTPSPEGETPGTPSLEPTERKRARSTSEAANPALDPNNPLHITLPTFRMVVLADELLEQFFDNYFPQSFHLSEQGAAAAQLPSLSSNLTTFSNIGAAKQQPTSSGPTVAGASGGIVPPNRGLRGVLDNIVTDGIRMAAEVKKRMDEAQRELERNALNRDDDDEDDEDDDGHHGTAPAIVGGISSWGAGAYGADPERRSVRETDRDLLEGAEVVNIRGKDDVSLLDDKDSHQESSSGQRTAAGSDDKVVSKVVEFES
What are the official names of this protein?
Putative GTPase-activating protein AN11010.
Protein: PETG_ATRBE
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: T3HPD_RHIME
Sequence: MRSTKTIHVISAHAEGEVGDVIVGGVAPPPGDTIWEQSRWIAREQTLRNFVLNEPRGGVFRHVNLLVPPKHPDADAAFIIMEPEDTPPMSGSNSICVSTVLLDSGILPMKEPVTEITLEAPGGLVRVRAECRDGKAERIFVENLPSFAERLDAKLEVEGLGTLTVDTAYGGDSFVIVDAAAMGFALKPDEAHDIARLGVRITNAANAKLGFHHPENPDWRHFSFCLFAGPVERTAEGLRAGAAVAIQPGKVDRSPTGTALSARMAVLHARGQMGLSDRLTAVSLIGSTFSGRILGTTEVGGRPAVLPEISGRAWITGTHQHMLDPSDPWPEGYRLTDTWGAR
What is the function of this protein?
Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C).  Can also catalyze the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp), albeit with 150-fold lower efficiency.  May be involved in the degradation pathway that converts t3LHyp to L-proline, which would allow R. meliloti to grow on t3LHyp as a sole carbon source.  Displays no proline racemase activity.
What are the official names of this protein?
Trans-3-hydroxy-L-proline dehydratase, T3LHyp dehydratase, t3HypD, Trans-L-3-hydroxyproline dehydratase.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: TRMFO_CERS1
Sequence: MAECLHIVGAGMAGSEAAWQAAEMGVPVVLHEMRPKVGTFAHRTGQFAEMVCSNSFRSDDDERNAVGLLHWEMRAARGLIMEMAAAHRLPAGGALAVDRDPFAESVTARLRAHPLISVVEEEVAELPSSGNWIVATGPLTSSALAESLRALTGAEALAFFDAIAPIVYAETIDMEVAWRQSRYDKGETEDERTAYINCPMNREQYEAFIDALLAAEKTEFHEGETAGYFDGCLPIEVMAERGRETLRHGPMKPVGLTNSHRPAEKAYAVVQLRRDNKLGTLYNIVGFQTKMKYGAQTAVFKMIPGLENASFARLGGIHRNTFLNSPTLLDDRMRLKLRPNIRFAGQVTGVEGYVESAAMGLLAGRMAAAEILGRDLPPPPPETAMGALVTHITGGAEAKSFQPMNVNFGLFPPIDARGGRRGRKDRYKAYTDRAKAAFTEWLGA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_BURVG
Sequence: MTDKLIIFDTTLRDGEQSPGASMTKEEKIRIAKHLERMKVDVIEAGFAASSNGDFDAIHTIAGLVKDSTICSLARANDKDIQRAADALKPASSARIHTFIATSPLHMEKKLRMTPDQVFEQARLAVRFARKFTDNVEFSPEDGSRSDLDFLCRVLEAVIAEGATTINIADTVGYGVPELYGNLVKTLRERIPNSDKAIFSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNTSLEEIVMAVKTRKDYFGLDVGIDTTQIVPTSKLVSQITGFVVQPNKAVVGANAFAHASGIHQDGVLKARDTYEIMRAEDVGWTANKIVLGKLSGRNAFKQRLQELGVSLDSEAELNAAFMRFKDLADRKAEIFDEDIIAIVSEESALAQEQEHVKFVSLSQHSETGEQPQAKVVFAVEGSEVTGEARGNGPVDATFNAIEGEVGSGSELLLYSVNAITTGTQAQGEVTVRLSKNGRIVNGVGTDPDIVAASAKAYIAALNKLHSKDDKLNPQRA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RPB2_SOLLC
Sequence: MDMEDEYEPQYNVDDDEEEITQEDAWAVISAYFEEKGLVRQQLDSFDEFIQNTMQEIVDESADIEIRPESQHNPGHQSDFAETIYKINFGQIYLSKPMMTESDGETATLFPKAARLRNLTYSAPLYVDVTKRVIKKGHDGEEVTETQDFTKVFIGKVPIMLRSSYCTLYQNSEKDLTELGECPLDQGGYFIINGSEKVLIAQEKMSTNHVYVFKKRQPNKYAFVAEVRSMADTQNRPPSTMFVRMLSRTSAKGGSSGQYIRATLPYIRTEIPIIIVFRALGFVADKDILEHICYDFNDTQMMELLRPSLEEAFVIQNQQVALDYIGKRGATVGVTREKRIKYAKEILQKEMLPHVGVGEYCETKKAYYFGYIIHRLLLCALGRRAEDDRDHYGNKRLDLAGPLLGGLFRMLFRKLTRDVRGYVQKCVDNGKDVNLQFAIKAKTITSGLKYSLATGNWGQANAAGTRAGVSQVLNRLTYASTLSHLRRLNSPIGREGKLAKPRQLHNSQWGMMCPAETPEGQACGLVKNLALMVYITVGSAAYPILEFLEEWGTENFEEISPAVIPQATKIFVNGTWVGIHRDPDMLVRTLRRLRRRVDVNTEVGVVRDIRLKELRIYTDYGRCSRPLFIVEKQRLMIKKKDIQTLQQRESPDEGGWHDLVAKGYIEYIDTEEEETTMISMTINDLVQARLNPGDAYSDTYTHCEIHPSLILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGIYVTNYQFRMDTLAYVLYYPQKPLVTTRAMEHLHFRQLPAGINAIVAISCYSGYNQEDSVIMNQSSIDRGFFRSLFFRSYRDEEKKMGTLVKEDFGRPDRASTMGMRHGSYDKLDDDGLAPPGTRVSGEDVIIGKTTPISQDDAQGQASRYTRKDHSTSLRHSETGMVDQVLLTTNADGLRFVKVRVRSVRIPQIGDKFSSRHGQKGTVGMTYTQEDMPWTVEGITPDIIVNPHAIPSRMTIGQLIECIMGKVAAHMGKEGDATPFTDVTVDNISKALHKCGYQMRGFETMYNGHTGRRLSAMIFLGPTYYQRLKHMVDDKIHSRGRGPVQILTRQPAEGRSRDGGLRFGEMERDCMIAHGAAHFLKERLFDQSDAYRVHVCERCGLIAIANLKKNSFECRGCKNKTDIVQVHIPYACKLLFQELMAMAIAPRMLTKDVKLAKDQKKKGA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB2, RNA polymerase II subunit 2, RNA polymerase II subunit B2, DNA-directed RNA polymerase II 135 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y128_LACLM
Sequence: MMNMQSMMKQAQKLQKQMQVSQEEIANTTFVGKSAQDLVTVEFSGDRTLKSLNINPDVIDPEDPETLQDMVTDAVNDALSQIEKVTEQKLGKFTKGLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein llmg_0128.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PORTL_EBVG
Sequence: MFNMNVDESASGALGSSAIPVHPTPASVRLFEILQGKYAYVQGQTIYANLRNPGVFSRQVFTHLFKRAISHCTYDDVLHDWNKFEACIQKRWPSDDSCASRFRESTFESWSTTMKLTVRDLLTTNIYRVLHSRSVLSYERYVDWICATGMVPAVKKPITQELHSKIKSLRDRCVCRELGHERTIRSIGTELYEATREIIESLNSTFIPQFTEVTIEYLPRSDEYVAYYCGRRIRLHVLFPPAIFAGTVTFDSPVQRLYQNIFMCYRTLEHAKICQLLNTAPLKAIVGHGGRDMYKDILAHLEQNSQRKDPKKELLNLLVKLSENKTISGVTDVVEEFITDASNNLVDRNRLFGQPGETAAQGLKKKVSNTVVKCLTDQINEQFDQINGLEKERELYLKKIRSMESQLQASLGPGGNNPAASAPAAVAAEAASVDILTGSTASAIEKLFNSPSASLGARVSGHNESILNSFVSQYIPPSREMTKDLTELWESELFNTFKLTPVVDNQGQRLYVRYSSDTISILLGPFTYLVAELSPVELVTDVYATLGIVEIIDELYRSSRLAIYIEDLGRKYCPASATGGDHGIRQAPSARGDAEPDHAKSKPARDPPPGAGS
What is the function of this protein?
Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging.  Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid.  Binds to the molecular motor that translocates the viral DNA, termed terminase.
What are the official names of this protein?
Portal protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae portal protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: HIS7_LEGPA
Sequence: MKKILFIDRDGTLVEEPFDFQVDSLDKIKLTSGVIPALLQLQKAGFTFIMVSNQNGIGTVAFPEEDFAVCHEFILDLFSSQGILFDEIFICPHTPEDNCICRKPKTGLLEPYLKETAFAKHYSWVIGDRDTDKEFADNLGVNFLPISKTHTWEMVVSAIINDARKASVQRKTKETAIDLSVQLDSDQTSVIDTPIPFFTHMLEQVAKHGGFDLRLQASGDLEVDEHHLIEDTAIALGEAIRTALGDKWGINRYGYTLPMDESLACVAIDISGRSFCDFKGQFTREFVGGMATEMVPHFFQSLSSALGATIHIEVTGTNHHHMIEACFKVLGRALRQACSRTNNYLPSTKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPOC_SOLLC
Sequence: MASLCSNSSTTSLKTPFTSLGSTPKPCQLFLHGKRNKAFKVSCKVTNTNGNQDETNSVDRRNVLLGLGGLYGVANAIPLAASAAPTPPPDLSSCSIARIDENQVVSYSCCAPKPDDMEKVPYYKFPSMTKLRVRQPAHEADEEYIAKYNCAVTKMKDLDKTQPDNPIGFKQQANIHCAYCNGGYSIDGKVLQVHNSWLFFPFHRWYLYFYERILGSLIDDPTFGLPFWNWDHPKGMRFPPMFDVPGTALYDERRGDQIHNGNGIDLGYFGDQVETTQLQLMTNNLTLMYRQLVTNSPCPLMSLVDLTLFGSTVEDAGTVENIPHSPVHIWVGTRRGSVLPVGKISNGEDMGNFYSAGLDPLFYCHHSNVDRMWNEWKATGGKRTDIQNKDWLNSEFFFYDENGNPFKVRVRDCLDTKKMGYDYHATATPWRNFKPKTKASAGKVNTGSIPPESQVFPLAKLDKAISFSINRPASSRTQQEKNAQEEVLTFNAIKYDNRDYIRFDVFLNVDNNVNANELDKAEFAGSYTSLPHVHRVGDPKHTATATLRLAITELLEDIGLEDEDTIAVTLVPKKGDISIGGVEIKLAIVKLVCVVNLLTLQLNKDRFCYDSVFVCWFVCLFFNFHV
What is the function of this protein?
Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.
What are the official names of this protein?
Polyphenol oxidase C, chloroplastic, PPO, Catechol oxidase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: PSA2_YEAST
Sequence: MTDRYSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKVSLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESVEGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQEINDRLEAL
What is the function of this protein?
The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  It has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-2, Macropain subunit Y7, Multicatalytic endopeptidase complex subunit Y7, Proteasome component Y7, Proteinase YSCE subunit 7.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EDN2_CANLF
Sequence: MPAPGVHHPNTASPFLKTVAAGKGQVAAAPEHPAPSARARGSHLRPRRCSCSSWLDKECVYFCHLDIIWVNTPGQTAPYGLGNPPRRRRRSLPKRCECSSGGDPACATFCHRRPWAEAVVVPGSRSPADVFQAGRTWTSAGELLRQLRNISAAKIRFPRRPQEAGRQLRPTHPRRRKR
What is the function of this protein?
Endothelins are endothelium-derived vasoconstrictor peptides.
What are the official names of this protein?
Endothelin-2, ET-2, Preproendothelin-2, PPET2.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUTF_ECOS5
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEKALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: DTD_THEPX
Sequence: MRAVVQRVIRGEVSVDGEVISSIGKGFVVLVGISVDDNENDVMYMADKIVNLRVFEDEEGKMNLSLLDIGGEVLLVSQFTLLGDVRKGRRPNFMMAQKPEEALKYFNLLVNEIEKRGVSVKTGKFQAMMKVLIENDGPVTILIDSKKIF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR12_DROPE
Sequence: MDVDNGEGQVQVHLKTKQEHYAVPDVPYAIDGTVTTAELNTFVNALLLSKGSSAVDFDFLVFDEYLRGRLCDHLREKAISFEDAIEIEYVERFPAPEPQDCLLHDDWVSAVKASGKWILTGCYDNTLNIWTNKGKHILTIPGHTAPIKAVDWISLDDDTGRFVSSSQDQTAMLWQWNVGANTVECVSVCKGHERGVDSVSVSPDGQRFATGSWDTMLKVWSAELEDAGEGTSKRMKESGVRTPKITLQGHRESISAVQWMDASTLLTGSWDHTLKVWDLSLEGIKAEISTNKSIFDASYSKLNHLILTASADKNLRLYDSRTNQGSVVRNTYLGHNAWVQTVMWSTTEEFLFVSGSYDNQNKLWDCRSPKAPLYDLLGHGEKVLDIDWTNPKYIVSGGSDNTVRVFKSRKALVENMDTK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.