PharMolix/UniProtQA huggingface dataset:
Protein: SSB_PAENI
Sequence: MAGETTITVIGNLTNDPELRFTPSGSAVANFTIASTPRTFDRQASEWKDGETLFLRASVWREMAENVAGSLTKGTRVIASGRLKSRSYETKEGDNRTVVELEVDEIGPSLRYANARVNRTQRSGNQNTRRTGDGSPGDAGQTASRDDPWAVNSPANAGSRSDGTDTEPPF
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: COX11_PONAB
Sequence: MGGLWRPGWRRVAFCGWRWIHPGSPTRAAERVEPFLRPECSGTGGAGRGLRWLGTWKRCSLGARHPALQPPRRHKNSNPFTRAQKEEWRRRNKTTLTYVAAVAVGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDKIENMVPVKDRIIKISFNADVHASLQWNFRPQQTEIYVVPGETALAFYRAKNPTDKPVIGISTYNIVPFEAGQYFNKIQQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMIKVDLITLSYTFFEAKEGHKLPVPGYN
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Protein: FRL3_ARATH
Sequence: MEDTRSVASLMDSTSSKIQQLQKAFAELESQRAVTLNLKWKELEEHFHGLERSLKRRFHELEDQEKEYETKTRKAQELLEKKKAAVEAKEKAALERLQKKRDAAMFTINSALDKYNNAPVSKPSVGERWPQNAVEDSSNVFAADSITDDNPDGIVQDVQISPVMGNYEVKAYPQLLKLCGDMDSTGLHKFVSDNRKNLASLKEEIPMAFRAAANPASLVLDSLEGFYPMEAPTADGKKDANLLGMRRTCIMLMECLSILLSGLDRNCLAVVLSQNVKHRAKTIAEGWNPLLESLDMDACNGNSLEAHAFLQLLATFAIVADFKEDELLKLIPMVSRRRQAAELCRSLGLAEKMPGVIEVLVNSGKQIDAVNLAFAFELTEQFSPVSLLKSYLIEARRSSPQGRPGNASPAVQDEFNERELIGLKTVIKCIEEHSLEEQYPVEPLHKRILQLEKAKADKKRATEPMKPQPKRPRGAQPRVTDNNNNINNNKTGYGRVIPERYPQYVYDNRPFLSGPIMAAQPPPPPPPQTYTFNPAPAHGNFYANCYQYQAPPPPPYFH
What are the official names of this protein?
FRIGIDA-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the Frigida family.
Protein: TX32C_CYRHA
Sequence: MKLCAVIIASLLVCVAVASSSDNQKEFAQEKEMTREETQSLGEHEKDDEVTGSEERSCIEEWKTCENDCECCGMSTLCAASWVDGHQIKLCRNVGGKLKKVLHFIQKSVSKIKSCKK
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XV-2, HNTX-XV-2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 02 subfamily. HNTX-XV sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TMP_BPSPB
Sequence: MSQNLKIILTPQADTSSKTVEQLNQQIKSLEKKLNSLKLNTNIDSTTLKALQEFSSAIDTYQKNLKSYNQTVKETSTVIKNADGSVEKLTQQYKKNGEILQRETKIINNRNTALKQETQEVNKLTQATEKLGQVQKKTVQRNLQGQPTKVVQKNRHGFDDIVYTTDPKTNSTSSKTTTNYDQQRRAIEQLKQDLEKLRQQGIVTDTTISSLGRKINTAQSAQQIEALQNRIRMLDDKSAAVAKNNELKKTIELYQRQAQVNVQNLNTRYGSSMGSSNRQAVQDYLNAVNSLNVSTGSNNIRSQIQSLNMQFRELASNAQTAANQASSFGAELTQTFKSMSTYLISGSLFYGAISGLKEMVSQAIEIDTLMTNIRRVMNEPDYKYNELLQESIDLGDTLSNKITDILQMTGDFGRMGFDESELSTLTKTAQVLQNVSDLTPDDTVNTLTAAMLNFNIAANDSISIADKLNEVDNNYAVTTLDLANSIRKAGSTASTFGVELNDLIGYTTAIASTTRESGNIVGNSLKTIFARIGNNQSSIKALEQIGISVKTAGGEAKSASDLISEVAGKWDTLSDAQKQNTSIGVAGIYQLSRFNAMMNNFSIAQNAAKTAANSTGSAWSEQQKYADSLQARVNKLQNNFTEFAIAASDAFISDGLIEFTQAAGSLLNASTGVIKSVGFLPPLLAAVSTATLLLSKNTRTLASSLILGTRAMGQETLATAGLEAGMTRAAVASRVLKTALRGLLVSTLVGGAFAALGWALESLISSFAEAKKAKDDFEQSQQTNVEAITTNKDSTDKLIQQYKELQKVKESRSLTSDEEQEYLQVTQQLAQTFPALVKGYDSQGNAILKTNKELEKAIENTKEYLALKKQETRDSAKKTFEDASKEIKKSKDELKQYKQIADYNDKGRPKWDLIADDDDYKVAADKAKQSMLKAQSDIESGNAKVKDSVLSIANAYSSIDISNTLKTSISDVVNKLNLKDDLDPEELEKFSSSLGKLQEKMQKALDSGDEKAFDNAKKDLQSLLETYSKSDSSIDVFKMSFDKAQKNIKDGDKSLSSVKSEVGDLGETLAEAGNEAEDFGKKLKEALDANSVDDIKAAIKEMSDAMQFDSVQDVLNGDIFNNTKDQVAPLNDLLEKMAEGKSISANEANTLIQKDKELAQAISIENGVVKINRDEVIKQRKVKLDAYNDMVTYSNKLMKTEVNNAIKTLNADTLRIDSLKKLRKERKLDMSEAELSDLEVKSINNVADAKKELKKLEEKMLQPGGYSNSQIEAMQSVKSALESYISASEEATSTQEMNKQALVEAGTSLENWTDQQEKANEETKTSMYVVDKYKEALEKVNAEIDKYNKQVNDYPKYSQKYRDAIKKEIKALQQKKKLMQEQAKLLKDQIKSGNITQYGIVTSTTSSGGTPSSTGGSYSGKYSSYINSAASKYNVDPALIAAVIQQESGFNAKARSGVGAMGLMQLMPATAKSLGVNNAYDPYQNVMGGTKYLAQQLEKFGGNVEKALAAYNAGPGNVIKYGGIPPFKETQNYVKKIMANYSKSLSSATSSIASYYTNNSAFRVSSKYGQQESGLRSSPHKGTDFAAKAGTAIKSLQSGKVQIAGYSKTAGNWVVIKQDDGTVAKYMHMLNTPSVKAGQSVKAGQTIGKVGSTGNSTGNHLHLQIEQNGKTIDPEKYMQGIGTSISDASQAEAERQQGIAQAKSDLLSLQGDISSVNDQIQELQYELVQSKLDEFDKRIGDFDVRIAKDESMANRYTSDSKEFRKYTSDQKKAVAEQAKIQQQKVNWIQKEIKTNKALNSAQRAQLQEELKQAKLDLISVQDQVRELQKQLVQSKVDETLKSIEKSSSKTQGKIKDVDNKISMTEEDEDKVKYYSKQIKLIQQQQKEAKKYIKQLEEQKKAAKGFPDIQEQITEEMQNWKDKQKDFNLELYNTKKSIKDIYKSLADEVVSIYKEMYEKMRDIELEAHQKATQDLIDEIDKTDDEAKFQKELKERQDSIQKLTDQINQYSLDDSEFGKSKVKELTEQLQKEQLDLDDFLKDRESNKRKEALQDQLEKDEESINNKYDNLVNDERAFKKLEDKIMNGKITDIAKQLNEFSKFINTNMESIGKSISNNLIDKLKEASNALNTAVKGNTTGKKVSSFASGGYTGTGLGAGKLAFLHDKELILNKTDTANILDTVKAVRETAVDDSPKWGQGVKLADLIKKGITSIPSLVPNVNQSMLTNSLIPNLKKIEIPSKTIASSGDKTINLTNTFHIDKLIGGESGARSMFESIKNEVVKLNGSM
What is the function of this protein?
Serves as a base for tail tube protein polymerization and acts as a template for tail length determination.  Exolysin involved in host peptidoglycan digestion necessary for viral DNA entry into the host cell (PubMed:14763988).
What are the official names of this protein?
Probable tape measure protein, TMP, Transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the P2likevirus tape measure protein family.
What are the subcellular locations of this protein?
Virion.
Protein: DVL23_ARATH
Sequence: MKMSERRVGSYRKSTLRCWDWCKEQRTRAYIIWRCLIFLLRWDDY
What is the function of this protein?
Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
What are the official names of this protein?
Small polypeptide DEVIL 23, Small polypeptide ROTUNDIFOLIA LIKE 13, Small polypeptide ROT-FOUR-LIKE 13.
What is the protein family that this protein belongs to?
Belongs to the DVL/RTFL small polypeptides family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: AKAP5_MOUSE
Sequence: METSVSEIQVETKDEKGPVAASPQKERQERKTATLCFKRRKKANKTKPKAGSRTAEETKKHTPEAGGSGQRQPAGAWASIKGLVTHRKRSEPAKKQKPPEAEVQPEDGALPKKKAKSRLKFPCLRFSRGAKRSRHSKLTEDSGYVRVQGEADDLEIKAQTQPDDQAIQAGSTQGLQEGVLVRDGKKSQESHISNSVTSGENVIAIELELENKSSAIQMGTPELEKETKVITEKPSVQTQRASLLESSAAGSPRSVTSAAPPSPATTHQHSLEEPSNGIRESAPSGKDDRRKTAAEEKKSGETALGQAEEAAVGQADKRALSQAGEATAGHPEEATVIQAESQAKEGKLSQAEETTVAQAKETVLSQAKEGELSQAKKATVGQAEEATIDHTEKVTVDQAEETTVGQAEEATVGQAGEAILSQAKEATVVGQAEEATVDRAEEATVGQAEEATVGHTEKVTVDQAEEATVGQAEEATVGQAEEATVDWAEKPTVGQAEEATVGQAEEATVGHTEKVTVDQAEEATVGQAEEATVGHTEKVTVDHAEEATVGQAEEATVGQAEKVTVDHAEEATVGQAEEATVGQAEKVTVDHAEEATVGQAEEATVGQAEKVTVDQAEEPTVDQAEEAISSHAPDLKENGIDTEKPRSEESKRMEPIAIIITDTEISEFDVKKSKNVPKQFLISMENEQVGVFANDSDFEGRTSEQYETLLIETASSLVKNAIELSVEQLVNEMVSEDNQINTLFQ
What is the function of this protein?
Multivalent scaffold protein that anchors the cAMP-dependent protein kinase/PKA to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors.  Association with the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade.  Plays a role in long term synaptic potentiation by regulating protein trafficking from the dendritic recycling endosomes to the plasma membrane and controlling both structural and functional plasticity at excitatory synapses.
What are the official names of this protein?
A-kinase anchor protein 5, AKAP-5, A-kinase anchor protein 150 kDa, AKAP 150, P150, cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein.
What are the subcellular locations of this protein?
Postsynaptic recycling endosome membrane; Lipid-anchor. Note=Associates with lipid rafts.
Protein: ACEA_PICPA
Sequence: MSGPYTKIDLDKEEQDFQNQIKEIEEWWSQPRWAKTKRIYNAEDIAKRRSSLSSVPASNQQAQKLFKLLGEHAKNETASFTFGALDPIHITQMAKYLDTIYVSGWQCSSTASTSNEPSPDLADYPMDTVPNKVERLILRRQLFHDRKQREERLSVSKQERAKLPYTDFLRPIIADADTGHGGITAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRTSADLFQSDLIAVARTDSEAATLLTSTIDKRDHYFVIGATNPDIPDLIDVLTEAELQGKYGAELSQLEADWSKKAGLKLYHEAVFEAIDKSSSVKDKQAAKDKFSAKVGPLTGTSHKEAAKLAKEILGEEVFFDWEAPKVREGYYRYQGGTECAIMRARAYSPYADLVWMESKVPDYQEAVDFAKGVKTFTQTNWLAYNLSPSFNWNKAMSPDEQETYIKRLGKLGYNWQFITLAVLHTTALAVDNFSRDYQKIGMKAYGQQVQAKEIEDGIEIVKHQKWSGAEYIDGLLKLTTGGLSSTAAMGAGVTEDQFKDH
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: UBIC1_BURP1
Sequence: MNTSSGWSRQPPASLSELEIHWLFAPGSLTERLSALGEYSLEPVDQRHAAACAADASLLGVEPDSPIWVREVVMRLDAQPCVTARSIASAHALETQWKPLTGYGSLPLGHILYDDPAIVRAPFECALLMPDDPLDAISRRYARAAAPPRARRSAFVRNGATLVVSECFLPQFWSGFAQARLAGA
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase 1, CL 1, CPL 1.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_PSEFS
Sequence: MTFDAARYTAQLQDKVTRLRDLLAPFDAPEPQVFDSPLQNFRLRAEFRLWREGGERHYAMFSQDDKRTPILIEEFPIASQRINQLMPQLKAAWQASAALSHKLFQVEFLTTLAGDAMITLCYHRPLDEHWHTAANKLATDLNVSIIGRSKGKRDVIGHDYVVEKLEVGGRTFSYRQPEGAFTQPNGTVNQKMLNWAYDALGDRPDDLLELYCGNGNFTLPLATRVRKVLATEISKTSVNAALSNLDENAVGNVTLVRLSAEELTEALNEVRPFRRLHGIDLKRYEFSSVFVDPPRAGMDPDTCELTRRFDNILYISCNPETLAANIAQLHDTHRITKCAMFDQFPWTHHMESGVLLTRR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: MURD2_SALTO
Sequence: MRLSDLRGRKVAVWGTGREGRAAVVAIAAHGPADLVAVDDGGSTVSPPWDGFLATAAPLVTGDAGAQRLAAADVVVRSPGVPNTHPWLAELWRRQVPVTQGTALWMADHAARTVGVTGSKGKSTTSSLISHLLAAVDQPNVFGGNIGVPTLDLPAADLYVLELSSYQCSDLTDSPRVAVVTALFPEHLDAHGGEREYYRDKLNLLAHGPETVVVNGADPRLAAELGDRPVVRAGTPDTTHVAGGPDGTPWFHLGDQPLFPRAVLPLVGRHNEGNLCVALAVLDVLGVDVLARRDTLAVAVAGFQGLAHRLTEIVDPSGLTFVDDTLATSPYAAMHAIDAYDGRALTVIVGGADRGLDYTPLRDHLAEREITVIGVPDSGARIVAALDGLPKVRCDVTGDLVEAVRLARRVTPAGGVVLLSPAAPSYGQFRNFEHRSEVFAQAVRDTAG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase, UDP-N-acetylmuramoyl-L-alanyl-L-glutamate synthetase, UDP-MurNAc-L-Ala-L-Glu synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_MAGSA
Sequence: MSDVAERVKKIVVEHLGVEEAKVTENASFIDDLGADSLDTVELVMAFEEEFSVEIPDDAAEKILTVKDAIDFITANS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTSC1_HUMAN
Sequence: MQSDIYHPGHSFPSWVLCWVHSCGHEGHLRETAEIRKTHQNGDLQIRGGRGRRESTEIFQVASVTEGEESPPAICMEVFLFLWFIAPIYACVCRIFKIQVRNTVKNSSTASLAPSISTSEERQIRIERHHYHLYGQ
What are the official names of this protein?
Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TIG_HAES1
Sequence: MSFNIETTQGLERRVNITVPSEAVEQAVREELKRVAKNARIDGFRKGKVPAQMIEKRFGASVRQDVLGDLLQKHFFNVMLENKVNLAGRPEFTVEQFEAGKELKFTATFEVYPEVQLQGLDKIKVEKPVVEISDADIDKMLDILRKQQATWIETQDVAKADDRVTIDFVGSVDGEEFEGGKSTDFVLAMGQGRMIPGFEEGIIGHKAGEQFEINVTFPETYHAENLKGKAAKFSITLKKVEVMQLPELTDEFVAKFGPNTKNVADLRNEIAKNMQRELKNALVSRIKTQVIDGLLEQNPIEVPTAAVEQEIEVLRNQAAQRFGGNAQQAAQLPRELFEEQAKRRVQVGLLFSEVISSNELKADEERVKAMIADIASAYEQPAEVIEYYSKNKELMNNIRNVVLEQQAVDAVLTKAQVTEKASSFDEVMNPQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RECX_PSEPU
Sequence: MSAVLDTPVAIRRTAMDLLARREHGRVELTRKLRQRGASDELIEPELDRLAEEGLLSEARYLESFIRYRSGSGYGPARIREELGQRGLARADIEQALRESEVDWAERMRDVWQRKFAGQRPQDRAAVPSRPDFSLTGASPWI
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSRB_ECODH
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNEAGHQDGIFVEKAE
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: RL21_SHIB3
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL22_DESVV
Sequence: MESRATAKFMRVSPRKTRLVARNIDGLPVEDAMNLLRFTPNKPAGVLYDVLRSALANAQQMPGVDVDAMVVKQVVVNEGPSWKRFLPRAQGRATRIKKRTSHITVILAEGQE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GG12C_HUMAN
Sequence: MSWRGRSTYYWPRPRRYVQPPEMIGPMRPEQFSDEVEPATPEEGEPATQCQDPAAAQEGEDEGASAGQGPKPEAHSQEQGHPQTGCECEDGPDGQEMDPPNPEEVKTPEEGEKQSQC
What are the official names of this protein?
G antigen 12B/C/D/E, GAGE-12B, GAGE-12C, GAGE-12D, GAGE-12E.
What is the protein family that this protein belongs to?
Belongs to the GAGE family.
Protein: SQE1_PANGI
Sequence: MNSSSSTTTTDTLHSFMEASALLIDQYFLGWIFAFLFGFLLLLNFKRKREKNNSTEFGTDDSNGYYTPENIAGSTDVIIVGAGVAGSALAYTLANDGRRVHVIERDLTEQDRIVGELLQPGGYLKLIELGLEDCVNEIDAQRVFGYALYMDGKNTRLSYPLEKFHSDVAGRSFHNGRFVQRMREKAASLPNVRMEQGTVTSLVEKKGSVKGVQYKTKDGQELSAFAPLTIVCDGCFSNLRRSLCNPKVEVPSCFVGLILENIDLPHINHGHVILADPSPILFYKISSTEIRCLVDVPGQKVPCISNGELANYLKTVVAPQVPKQLYNSFIAAVDKGNIRTMPNRSMPADPHPTPGALLLGDAFNMRHPLTGGGMTVALSDIVLIRDLLRPLRDLHDSSTLCKYLESFYTLRKPVASTINTLAGALYKVFCASPDKARQEMRNACFDYLSLGGICSQGPIALLSGLNPRPISLFLHFFAVAIYGVGRLLIPFPSPKRMWLGARLILGASGIIFPIIKSEGLRQMFFPAIVPAYYRAPPIH
What is the function of this protein?
Component of the triterpene saponins (e. g.  ginsenosides or panaxosides) and phytosterols biosynthetic pathways (PubMed:19857882, PubMed:27746309, PubMed:29378087).  Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway (By similarity).
What are the official names of this protein?
Squalene monooxygenase SE1, Squalene epoxidase 1, PgSQE1, SE, SE1, gse.
What is the protein family that this protein belongs to?
Belongs to the squalene monooxygenase family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CHSY_FRAAN
Sequence: NITDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRHILSEYGNMSSACVLFILDEVRRKSAANGHKTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase RJ5, Naringenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: KTU_ANOGA
Sequence: MSTKDFNISRDEFRNITRCLDNEEFRNLFMEYCTELRDNRKQYEDELSMLEAQRGYDVKFLKPSPGYVIKTIVDGKGKGFINVCQSELVQKPTSTTGLNEDGTKGLKWSVPYAQTQPRKDYDNKRVECTVYDVMFHPDALHLASKNEGFRKLLNDTSLDAVEQSFKVRLDRANLRFPKLQYKGTPSSSVVREKLPHCDSLPKDELFDKLLPPLPNVPAPGKTGSERTTKTKNKENINRTAAVAAAAASPGNPFYTTPEYKIVQCRDVEYGEMTNELDAKIDVTIPRELKVVITLPLLKSTAECALDVTKTTLHLVSEKPARYKLELKLPYEVKESEGKATFNVEARSLTVTLPVLRKRNITLQDINSANVSASPAKEAGKLIEEIGTIIPPAGGDQQLARAASAPSAPEVPKKTIFPKFSVNKMENLLAFTLNVRNVDPSTIQLDNRTDSVHCRFSNVGNGYFPCFYVFFVRFPNALVTDVQHEEWDNNLIIQITLNTASVSSYQAGPDEHETVEYSIMEDIADKINKFGKEIEDDSLCIAVVRQATKASAKVKADALMSIEITKREEHGEPECDEKDGSEAEKARTLQKAKRNSRKKKKERSLSDSFCDHLKVIVENEASTEVAGEGATIQSSAKPIDSPEAKARKARSISECCPPKESDGGEEASTMPTLTRKYKSILKRSSYDRSISECSSVDDLGTSVEMARSIGEECRKTVRFNNSIRKQLFRSNSCILTMKKKALKRREVKRRADARRMSEGESTDNDEKDAHHHDDEHCSSSDQHDEKDAIEDDSGVSFDSESGDKEIAAAMKAEAIGGGGRGKAASKRKNSNKQGGAKSNGGKKQGTDAKNIQFKSDMIFDIEI
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal homolog.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODP2_RAT
Sequence: MWRVCARRVQSAVPRAGFRARWATLKGPRTGPAAVRCGSGIPSYGVRSLCGWSYGSATVPRNRILQQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYTLDSATAATQAAPAPAAAPAAAPAAPSASAPGSSYPVHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKQEDIAAFADYRPTEVTSLKPQAPPPVPPPVAAVPPIPQPLAPTPSAAPAGPKGRVFVSPLAKKLAAEKGIDLTQVKGTGPEGRIIKKDIDSFVPTKAAPAAAAAAPPGPRVAPTPAGVFIDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKELNKMLEGKGKISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLIPADNEKGFDVASVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPVTMLL
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis, PBC, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2, PDC-E2, PDCE2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MRES1_HUMAN
Sequence: MAMASVKLLAGVLRKPDAWIGLWGVLRGTPSSYKLCTSWNRYLYFSSTKLRAPNYKTLFYNIFSLRLPGLLLSPECIFPFSVRLKSNIRSTKSTKKSLQKVDEEDSDEESHHDEMSEQEEELEDDPTVVKNYKDLEKAVQSFRYDVVLKTGLDIGRNKVEDAFYKGELRLNEEKLWKKSRTVKVGDTLDLLIGEDKEAGTETVMRILLKKVFEEKTESEKYRVVLRRWKSLKLPKKRMSK
What is the function of this protein?
Mitochondrial RNA-binding protein involved in mitochondrial transcription regulation.  Functions as a protective factor to maintain proper mitochondrial RNA level during stress.  Acts at the transcription level and its protective function depends on its RNA binding ability (PubMed:31226201).  Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation (PubMed:33243891, PubMed:31396629).  As heterodimer with MTRF, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes.  Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue (PubMed:33243891).
What are the official names of this protein?
Mitochondrial transcription rescue factor 1.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RS17_STRPZ
Sequence: MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKKYKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DPH5_HUMAN
Sequence: MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester.  The four successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine methyl ester synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: RNH2_STRP1
Sequence: MPTSIKAIKESLEAVTSLLDPLFQELATDTRSGVQKALKSRQKVIQAELAEEERLEAMLSYEKALYKKGYKAIAGIDEVGRGPLAGPVVAACVILPKYCKIKGLNDSKKIPKAKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLEGQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFPGYDFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.