PharMolix/UniProtQA huggingface dataset:
Protein: ACEK_PECAS
Sequence: MTRDLEKLVAQTILQGFDAQYGRFLEVTAGAQQRFEQADWPAVQQAMKQRIHLYDHHVGLVVAQLRCITGIRCDDADFLARMKHIYTGLLPDYPRFEIAESFFNSVYCRLFNHRELAPDKLFVFSSQPEKRFHEIPRPIAKTFVPTDGWQRMLEKLLGDVPLRLPWEDLPRDIDYIVTYLQSTFSAEQLEQATLQVANELFYRNKAAWLAGKLSLPDGVFPFLLPIHHNERGALFIDTCLTAQADASMVFGFARSYFMVYAPQPSALVAWLRDILPGKTTAELYLAIGCQKHSKTEYYREYLHYIAESEEQFIIAPGVKGMVMLVFTLPSFDRVFKVIKDRFAPQKEVSAERVMACYQLVKEHDRVGRMADTQEYENFVIDKHRISPELLDELWREVPEKLEDLGDQLVIRHLYMERRMTPLNLYLEQANAQQLHDVIEEYGNAIKQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRKIPPPRYLEDELAAEPWYSVAPNDVFPEEFPHFLCSDRHIRTLFEEMHGDLFCADYWRALQQRIREGHIEDVYAYRRRKRFSQRAEPLYITTENDSGLCRYPA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCS_ECOLU
Sequence: MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.  Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STX4_SCOVN
Sequence: AKEKEVTFQSGGPT
What are the official names of this protein?
Scolopendra 5885.28 Da toxin.
What is the protein family that this protein belongs to?
Belongs to the scolopendra toxin 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSCA_NEIMA
Sequence: MALLQISEPGMSAAPHRHRLAAGIDLGTTNSLVATVRSGSAACLPDAEGRVTLPSVVRYLENGGIEVGKTALSAQKTDPLNTVSSAKRLIGRTLADLHQNTHYLPYRFGDNQRVIELHTRQGVKTPVEVSAEILKTLKSRAEETLGGDLVGVVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNASEGTFVVYDLGGGTFDVSVLQLTKGLFEVKATGGNSALGGDDFDHRLFCRLLEQNGLSQLNEQDSQLLLSLVRAAKEQLTTQTEARIQATLSDGMPIDTSISRAEFHNLTQHLVMKTLEPVTQALKDAGVGKNEVKGVIMVGGSTRMLHVQQAVATFFGQTPLNNLNPDEVVALGAAIQANVLAGNKTDGEWLLLDVTPLSLGLETYGGLAEKIIPRNSTIPTARAQDFTTFKDGQTAMTIHVVQGERELVSDCRSLAKFTLRGIPPMAAGAARIRVTFQIDADGLLSVSAQEQSTGVQAQIEVKPSYGLDDGAITRMLKDSMDNAAEDMAARARAEAVVEAESLTDAVNAALELDSDLLDAKELQQIRQGIADLQGRLKDGKAEDIRSAVAKLSRSTDNFAAKRMNRNIQRALTGQSVDNI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RNY_THET8
Sequence: MSLLDLVLLLLVLGLGGVLLLRRKGEDRSAQEARELLEAARREAREVLEAARKEARDILEAARQEAKALRQEAEARAKAQREEVEAELRRRLEAAEAEAKKRLEEAGERLKAEREELRAERERLRSLQEELKEERERLKAEREELRREGERLAKRAEALDARAARLEEAEAELVRKEEALKAEARALEERLKEVERRLYEVAGLTPEEARRLVLERLDRELEEEKAQRVRAALERARLEARREAQKILAQAMQRQASETAAQLAVTVVPIPSDAMKGRIIGREGRNIRAFEALTGVDLIIDDTPDAVLLSSFNPIRREIARMALEELLKDGRIHPSRIEEVVEKAKQEMKTFIYERGEEAALEAGVVGLKPGLIQLLGRLHFRSSYGQNVLKHSIQVAHLAGIMAAELGLDAALARRAGLLHDIGKSVDREVEGSHVEIGIALARRFGEPKEVVDAIAHHHDPDNAETLYAVLVAAADALSAARPGARRESLEEYLQRLEALERIALSFPGVETAFAVQAGREVRVIVKPEKISDAKATLLAREIASRIEKEMNYPGQVQVTVVRETRAVEYAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYT13_RAT
Sequence: MVLSVPVIALGATLGTATSILALCGVTCLCRHMHPKKGLLPRDREPDPEKARPGVLQAAQQFNVKKSTEPVQPRPLLKFPDIYGPRPAVTAPEVINYADYTLGTTEESAAPASPQAQSDSRLKRQVTEELFILPQNGVVEDVCVMETWNPEKAASWNQAPKLHFRLDYDQKKAELFVTSLEAVTSDHEGGCDCYIQGSVAVKTGSVEAQTALKKRQLHTTWEEGLTLPLGEEELPTATLTLTLRTCDRFSRHSVIGELRLGLNGASVPLGTAQWGELKTTAKEPSAGTGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQAQKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQGEEGPSCELGRCSLGLHASGSERSHWEEMLKNPRRQIAMWHQLHL
What is the function of this protein?
May be involved in transport vesicle docking to the plasma membrane.
What are the official names of this protein?
Synaptotagmin-13, Synaptotagmin XIII, SytXIII.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ISPE_THESQ
Sequence: MVENIGSGSAELVSYAKLNLYLDVLGKRSDGYHEIVGLFQTISLHDTLTVEICDRGFYLESSVALPSDNTIKRAWEMFRKNTGKEFGLKVTLKKKIPVGSGLGGGSSNAAAVLRYLGEVFKIPLEDLLNIAAQVGSDVPFFLYGGTALVRGRGEIVEKLEDIEGYSVDLFFPGIHSSTKEMYLSLTPEMYRKGPGRVEELHRAYLERDYEKIRKLSYNVFEKVFLEKHPEVMDGLRNFGDGSIVKMMTGSGSAFFALYPLDKGNYSFVGGV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: FOXO_DROYA
Sequence: MMDGFAQDWPTLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTCSVADELTLCTQQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQSPYALNGPAPGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQQQQQQQQQLSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNISNISNLSNLSNISNISSNSGSSLNLNQLQAQLQQQQQQQQAQLQQQAQQQQQPHQQHQQQLLLNNNNNSSSSLELATQTASSNLNARVQYSQPSVVTSPPSWVH
What is the function of this protein?
Transcription factor involved in the regulation of the insulin signaling pathway.  Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR.  Involved in negative regulation of the cell cycle, modulating cell growth and proliferation.  In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.  Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging.  Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis (By similarity).
What are the official names of this protein?
Forkhead box protein O.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation (By similarity).
Protein: MIAA_TOLAT
Sequence: MTDPRHPPVIFLMGPTASGKTALAIELVKRLPCDIISVDSALIYRGMDIGTAKPTAEELAQAPHRLLDIRDPFQTYSAADFRQDALREIETIVAQGRIPLLVGGTMLYYKALLEGLSPLPAADPLIRQAIEAEASLSGWEALHAQLQSIDPVAAARIHPNDPQRLSRALEVYRISGQTLTELTQTKGEQLPYRTLQFAIAPTDRELLRQRIAERFHLMLSQGFEQEVRALYDRGDLNADLPSIRCVGYRQMWEYLDGQISYDEMVYRGIVATCQLAKRQMTWLRSWQNVTWLETGAINNADIICHSLTSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TRPD_CELJU
Sequence: MDIKQALKKLVASIDLSTEEMISVMRIVMTGGATPAQIGGFLVALRMKGETLDEITGAAMVMRELATPVNIDVDYLVDTCGTGGDGANLFNLSTASAFVVAAAGGRVAKHGNRSVSSSTGSADVLEAAGIKLDITAEQVARCVKEIGVGFMFAPSHHSAMKHAIGPRRELGMRTIFNMLGPLTNPANVKRQVIGVFNGELCKPMAEVLGRLGSEHVMVVHAKDGLDEISLATETQVAELKGGEIREYIIKPEDFGMQSKSLIGLSVSNAEDSLLLIRDALGNRRGQYAEKAADIIALNAGAAIYVSGVAGSLSDGVEMARDAIGSSLAGEKIRELAAFTQYLQ
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: EFP_FLAPJ
Sequence: MASTSDIRNGLCIKFNHDIYKIIEFLHVKPGKGPAFVRTKLRSLSNGKVLDNTFSAGHKIDEVRVETHTYQYLYAEGDQFHFMNIESFEQITLDKKILDNPGLLKEGTNVMVQVNTETDLPLSVDMPASIILEVTYAEPGVKGNTATNATKSATVETGASINVPLFINEGDKIKIDTASGSYMERVK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_STRGC
Sequence: MSLQEEIIAQLGVKPIIDPEEEIRKSVDFLKAYLRKHPFLKSYVLGISGGQDSTLAGRLAQLAVEEMRAETRDDSYRFIAVRLPYGVQADEDDAQKALTFIQPDVSLTVNIKESADAMTRAVEATGAKVSDFNKGNIKARSRMIAQYALAGSYSGAVIGTDHAAENVTAFFTKFGDGGADILPLYRLNKRQGKQLLAALGADPALYEKVPTADLEEEKPGIADEVALGVTYNEIDDYLEGKSVSAQAQETIESWWHKGQHKRHLPITIFDEFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: ARNT_SALPA
Sequence: MKSIRYYLAFTAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRTGKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLCHSPKYLLPAFCPLGLALLFGFSVPDRVMESKQPQFFVEMTQAPLASSRYILADSVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQNKFVKADDFNAWLNQHRQEGIITLVLSIDKDEDISALSLPPADNVDYQGRLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYV_BIFLS
Sequence: MTEGKSIINANLTPLPDKVGVDGLEDKWRAVWDEDGTYKFRNTRDRKAVYSIDTPPPTVSGSLHVGHVFSYTHTDVIARYKRMRGYDVFYPMGWDDNGLPTERRVQNYYGVRVDVSLPYDPDFKPPFEGTDGKKIDAKDQVPISRKNFIELCERLTAQDEKLFEALWRKLGLSIDWSQTYHTIGQHPQRVAQKAFLRNLARGEAYQQDAPGLWDVTFQTAVAQAELESREYPGFYHKVAFRFEDGTPIYIETTRPELLAACTSLIANPNDERYKQYFGQYVYSPLFKVKVPILAHPAAEMDKGAGIAMCCTFGDVTDVEWWRDLKLPTRPIIQRNGRIVMDTPDWIEDPAGREVFAETAGKTTFSARKIIVDKLRESGDLDGEPTPTKRMTNFYEKGDKPLEIVTSRQWYLKNGGTDAKLNAELIERGKELEFHPDFMRVRYENWVHGLNGDWLISRQRFFGVPFPLWYPVNASGEPDYDHPITPSEDRLPIDPTIDVPEGYDESQRDVPGGFTAEKDIMDTWATSSLTPQIVTHWAEPDEASQALFKSTFPMDLRPQGQDIIRTWLFSTVDRAHLENKCLPWAHATLSGWILDPDHKKMSKSKGNVVVPNEPIEKFGADAVRYWAAAARLGLDATYDIGQMKIGRRLAIKLLNATKFALAIGREDENHHVGAAAEAAWNPADVTEPLDRAAMAKLAVVVRQATEALESYEHSKALEVIESYFWQFCDDYIELVKNRAYGTPDEHGNVPSEKAVKSARTALGLGLDAFARLLAPYLPYATEEVWSWMHAGSGSVHRAAWPVVDPYVEAATGASPELLTWAGKAVEQLRKIKSEAKVSMKTPILSVALSAASEGVDAIHAALGDIAQAGRVVGKFDLVAKHAEESAAEDAPETEVAVEASELGEPPVKKPKH
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_SHESR
Sequence: MSPSPFAPTIETIDYPFPPKPIPLSDAEKADYKASIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFSAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKANALRDLKRVYPDAAILVHPESPASVVAMADAVGSTSQLIKAAQTMANERFIVATDRGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHCPWMAMNGLKAIEASLSDSDKTTHEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI_ACIAM
Sequence: MEFKIIAEYFDRLEKISSRLQLTSLLADLFKKTDKNVIDKVVYIIQGKLWPDFLGMPELGIGEKFLIRALSIATSVSDDEIEKMYKSVGDLGQVAFDIKQKQQSASILAFLGAQKASKPLTVEKVYDDLAKVATSTGEGSRDIKIRLLAGLLKDASPLEAKYLVRFVDGRLRVGIGDATILDALAITFGGGQNFRPIVERAYNLRADLGNIAKILANGGIEQLKNIKPQPGIPIRPMLAERLSDPAEMLSKVGNIALVDYKYDGERGQIHKAGDKIFIFSRRLENITNQYPDVAEYISKYVKGNEFIVEGEIIPVDPETGEMRPFQELMHRKRKSDIHEAIKEYPVNVFLFDLMYYEGEDYTVKPLSERRKKLESIVEDNDYVHIATHIITDNVEKLKEFFYQAISEGAEGVMVKSLAPDAIYQAGSRGWLWIKFKRDYQSEMADTVDLVMVGAFHGKGRKGGKYSSFLMAAYNPDKDVFETVCKVASGFTDAELDDLQKKIAELKRDTPHPRVVSTMVPDVWLTPALVAEIIGAEITISPLHTCCKDQYAEGGLSIRFPRFIRWRPDKSPEDATTNREILEMYKSQLKKIEEKPSDQSV
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: AMYR_DROEL
Sequence: MFKFALALTLCLAGSLSLAQHNPHWWGNRNTIVHLFEWKWSDIAEECESFLGPRGFAGVQVSPVNENIISAGRPWWERYQPISYKLTTRSGNEEEFGDMVRRCNEVGVRIYVDVLLNHMSGDFDGVAIGTAGTEAEPSKKSFPGVPFSAQDFPPSCEITDWNNRFQVQQCELVGLKDLDQSSDWVRSKLIEFLDHLIELGVAGFRVDAAKHMASEDLEYIYRSLSDLNTDHGFPHNARPFIFQEVIDHGHETVSRDEYKDLGAVTEFRFSEEIGNAFRGNNALRWLQSWGTGWGFLPSGQALTFVDNHDNQRDAGAVLNYKSPRQYKMATAFHLAYPYGISRVMSSFAFDDHDTPPPQDAQERIISPEFDEDGACVNGWICEHRWRQIYAMVGFKNAVRDTEMAEWWDNGDSQISFCRGNKGFLAVNNNQYDLSQELNTCLPAGEYCDVISGSLINGSCTGKSVTVKDNGYGYIHIGVDDFDGMMALHVDAKV
What are the official names of this protein?
Alpha-amylase-related protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RT03_USTMA
Sequence: MPTIPSVYRLQQPQMQLNGVAPTHSFSKQYPGLGSTVSGNTSLNNSAICIINAYASGGTLNKKNTTKKNNTVSNNNSVSTTSFFISKPNFSHTNSKVTIQLFYYTASPKNHLVNTSNNDLTTVSSHFSDLSTTLAQLYQKEVHVIATRLYYPYLNSDILSQYLAHNGPSNTFMDFQEAILTNPSLHKTNLPAHISGIKVQVSGRLVTETVIPRITVKSYLIGSFQRNSNNTANKLGDFVTSIDYSKFTTKNELGAFTVKVWICQRS
What are the official names of this protein?
Ribosomal protein S3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BADH_HORVU
Sequence: MAAPPAIPRRGLFIGGGWREPTLGRHIPVINPATEDTIGDIPAATAEDVELAVAAGGPVLARRREPWARASGATRAKYLNAIAAKITGKIAYLALLETVDSGKPKDEAVADMDDVAACFEYYAALAEALDGKQHAPISLPMEEFKTYVLKEPIGVVGLITPWNYPLLMATWKVAPALAAGCTAVLKPSELASLTCLELGAICEEIGLPSGVLNIITGLGPDAGAPIASHPHVDKIAFTGSTATGKTIMTAAAQMVKPVSLELGGKSPLVTFDDVADIDKAVEWPMLGCFFNGGQVCSATSRLLLHEKIAEPFLDRLVEWAKNIKISDPLEEGCRLGSVISKGQYEQIKKFISTARSEGATILHGGDRPKHLGKGFFIEPTINTGVSTSMQIWREEVFGPVICVKVFKTESEAVELANDTHYGLAGGVISDDLERCERIAKVIHSGIVWKNCSQPTLVQAPWGGNKRSGFGRELGEWGLENYLSVKQVTRYCKDELYGWYQRPSKL
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: SC61G_BRABE
Sequence: MDQLVQFVEPARQFAKDSYRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIIVGS
What is the function of this protein?
Necessary for protein translocation in the endoplasmic reticulum and multi-pass membrane protein biogenesis.
What are the official names of this protein?
Protein transport protein Sec61 subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NU2M_COTJA
Sequence: MNPHAKLISIMSLALGTSITISSNHWILAWTGLEINTLAIIPLISKSHHPRAIEAAIKYFLTQSTASALILFSSMNNAWSTGQWDITQLNHPTSCLILTMAIAIKLGLVPFHFWFPEVLQGSSLITALLLSTLMKLPPMTLLLMTSQSLNPALLTLLAVSSALVGGWMGLNQTQTRKILAFSSISHLGWMIVIIIYNPKLTILTFIIYSLMTSTVFLSLSQIKVLKLSTMLISWTKTPMLNSTIMVTLLSLAGLPPLTGFMPKWLIIQELTKQEMTPVATTIAMLSLLGLFFYLRLAYHSTITLPPNSSNHMKLWRINTTPNTPTAILTVLSISLLPLSPLITTLV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FRDA_HUMAN
Sequence: MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGLNQIWNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
What is the function of this protein?
Modulates the RNA-binding activity of ACO1 (PubMed:20053667).  May be involved in the cytoplasmic iron-sulfur protein biogenesis (PubMed:16091420).  May contribute to oxidative stress resistance and overall cell survival (PubMed:16608849).
What are the official names of this protein?
Frataxin, mitochondrial, Friedreich ataxia protein, Fxn.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm, cytosol. Note=PubMed:18725397 reports localization exclusively in mitochondria.
Protein: GCY28_CAEEL
Sequence: MLRWLTLLSCILLTALHGNIVEDVGAAQQASYPPPPPPFPFNVIVILPKRESTYDNFGMTLQKAMPVIDIAVQEVIKAKKLPPGWINLTYWDSRLYEDILLAERHATVGVIQAYCEHRLDAILGFADNYGLATVTKVTAGLNGGIPILTTSGMPSLLNSKKEYPFLTRMQGSYRLLADSMYQLIAYHDEDSVSKSNSSLNYLNLIFFYHDKRRAVNRVIAQDESQETGATSSHCYFSLYAIKRYFTEKSKTFKREWALNTPQFPFDEDLVIERETFKQWLREISLQSNVIILCASPDTVREIMLAAHDLGMATSGEYVFINIDVSTGSHAEQPWIRANDTNNEENEKAKEAYRALKTISLRRSDLDEYKNFELRVKERADQKYNYTNITGKDYEMNNFISAFYDAVLLYAIALNETIQSGLDPRNGHNITSRMWGRTFVGITGNVSIDHNGDRYSDYSLLDLDPVQNRFVEVAYYSGASNQLKTVGQLHWVGGKPPTDLPICGYDKSKCPGYPLHVYLLMGSFLLILVLVGLFIFFWRRYKLEQELAAMSWKIRWEELDGEESQKKNEKKKAKKRKNHNDYLPESDPLLRSTSRSSVNSDKFDEDSLIPIRFRLRSSSSGTTRKISAMIDRKLSIFTRKKSTPPSESQKNGGLTPNSLQKAENGDCSPINEVQFRLPLNDRRVSSPSSEATRKKNSNEEDPENGAKKSLSLKNRKLSFGMVSFKSGSGGSVETIAQNNTQIYTKTAIFKGVVVAIKKLNIDPKKYPRLDLSRAQLMELKKMKDLQHDHITRFTGACIDFPHYCVVTEYCPKGSLEDILENEKIELDKLMKYSLLHDLVKGLFFLHNSEIRSHGRLKSSNCVVDSRFVLKVTDFGLHRLHCLEEINLEEIGEHAYYKKMLWTAPELLRDSNAPPMGTQKGDIYSFAIILHEMMFRKGVFALENEDLSPNEIVQRVRKPVSEDQEPLRPWVSETGEGEGDDALNDTLLSLMVACWSEDPHERPEVSSVRKAVRSLNRDNETSNLVDNLLKRMEQYANNLEGLVEERTQEYLAEKKKVEELLHQLLPPAIADTLIAGRAVQAESYDCVTIYFSDIVGFTSLSSQSTPMQVVTLLNDLYLAFDGVVDNFKVYKVETIGDAYMVVSGLPERRDDHANQIAQMSLSLLHKVKNFVIRHRPHEQLKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQTYDILMQEAGFKLELRGSVEMKGKGMQTTYWLRGYKDVEIPDFGEEFA
What is the function of this protein?
Regulates sensory integration of conflicting sensory cues in AIA interneurons (PubMed:21414922).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-28, GCY-X1.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
[Isoform c]: Cell membrane; Single- pass type I membrane protein. Cell projection, dendrite. Cell projection, axon. Perikaryon. Note=Excluded from the neuronal sensory cilia. SUBCELLULAR LOCATION: [Isoform d]: Cell membrane; Single- pass type I membrane protein. Cell projection, dendrite. Cell projection, axon. Perikaryon. Note=Enriched in the axon of AWC sensory neurons. Is excluded from the neuronal sensory cilia.
Protein: ISCS_METCA
Sequence: MKLPVYLDYSATTPVDPRVAEKMIPFLTENFGNPASRSHTFGWTAEQAVENAREEVAKLVNADPREIVWTSGATESDNLAIKGAAEFYQTKGRHLITVKTEHKAVLDTMRELESSGFEVTYLEPMANGLLDLDAFRAAIRPDTVLASVMQVNNEIGVIQDIAAIGGICREHGVIFHVDAAQATGKVEIDLEQLPVDLMSFSAHKTYGPKGIGALYVRRKPRIRLKAQMHGGGHERGLRSGTLATHQIVGMGEAFRIAREEMAAENERIRRLRDRLLAGLADMEEVFINGDLEQRVPHNLNISFNYVEGESLMMAIKDLAVSSGSACTSASLEPSYVLRALGRSDELAHSSIRFTLGRYTTAEDVDFAISLIKDKVARLREISPLWEMYKDGIDLNTVQWAAAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.