PharMolix/UniProtQA huggingface dataset:
Protein: SEC13_PHANO
Sequence: MADNGQNVDLLSIEANEVQHDAVLDYYGRRLATCSSDKTIKIFEVEGDKHTLVETLRGHEGPVWCVAWAHPKYGNILASSSYDGKVIIWREQSSTWQKIYEVALHTASVNIVAWAPHEVGCLLACASSDGNVSVLEFKDNAWSHVIFQACGSGVNSVSWAPAVAPGQVVSASGNQAGAARRFVTGGSDCQVKLWDFSAETGSWQSTQILTGHTDWVRDVAWSPTVLSKSYIASASQDKTVRIWTSSDLRDWKSTVLNVDAVAWRVSWSLSGNVLAVSTGDNRVSLWKERLSGGWECVKTIEE
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: YIM1_ZYGRC
Sequence: MSKVINRAVTFINNKTPATITTKELDLDRCFKDTEIVIKIHAASLNPIDVMVHNLAFKLPFNSSPKTFSRDYAGVIVKAGDKVDPEWKINDRVVGNFAHIYGEQGTLSDYLILDPSVQKAIAHIHDTTKLDTKYDPFTLNAAWPLVFGTAHTALFDYGQKLGPDSKILVIGASTSVSYALVHIAKNVLNVGTVVGICSSQSFEHNKAAGFDHLVPYDQGPLTEEVGKLLVGTLRNEKFDLIFDSVGNNDFFPVMDKFLKPKSENSYYISISGDYKNNFNKHPFNISSARSLFRAANPFRGYNYALETLPCKREYMDLGAKLIADGKYAPKIDSVYNFDDYQKAMDRLKSNKAKGKVVIKINGEK
What are the official names of this protein?
Protein YIM1.
What is the protein family that this protein belongs to?
Belongs to the YIM1 family.
What are the subcellular locations of this protein?
Lipid droplet. Mitochondrion.
Protein: RL37_SULIY
Sequence: MKGTPSFGKMNKSHTHIRCRRCGRNAYNVSKHYCAACGFGKTKKIRRYSWQNKKVNGVRIR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: MINE_SHEB2
Sequence: MSLLDYFKSKKKPSTAVMAKERLQIIVAHQRGQRDTPDYFPQMKQEIIAVIRKYVQISDDQVSVQLDQNDANLSVLELNVTLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: DBF4A_XENTR
Sequence: MKSTVATVKNPTGKVQADICKPFSGKVFYLDLTSKLISEKLEKDIKELGGTVEGFLSKEISYLITSKKEAKCVKTLKYVCSVPSPEPAQNTGESSTSPGNRRLPQEGNSSKKNEKSLVSRGKSLVKKAIKEQEILPKNSILSNALNWGVKILHVEEAKRYIEKKKSSLQQVKKSQPVVKSESKHPARRKVKPQKLKSPYIKVEDCSCQYRPLYLVLPQFRSFQNTTSNYLVEVDKKADVGQKLAETKQSINKTGHVQDGANNANIKLKEQKKHGYCECCLKKYDSLESHILSPQHKNYSESAYYQVVDDLISTFEFDFVDWSKYKNGRKSVGILMLTEKYKAEGQERNEASKANTFSERVSATTPLQENTLKDPYATSCSVPPTPVCNTDPMFSLPSPVGSAELCNKKYTTDNFEQLVATSVPALCLKDNLPGSLGEREMSVVYNETKQNETIDHTMERPKIGWDASNIPSNILLYVPQKVDAVAQYANVSLKGNIHCSKLTACQAALTYGKMDPAVCDNITFPKTVNHLHNKEGHRTMDQIYPTVQSDELQSLLPDYSPSGNLHRKLKTSAQTNLADDELLCRLSHKVSVPQQNDVLNVPSETLLAMFESSEDKTEFFGFAGSCVCDPCSMDDGDNRDQAHKNLLLSLFSHTTTSGSSFLGF
What is the function of this protein?
Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation.  Not required during the initiation of DNA replication in egg and during early embryonic development but is required later throughout development.  The complex cdc7-dbf4a phosphorylates mcm2 subunit (By similarity).
What are the official names of this protein?
Protein DBF4 homolog A.
What are the subcellular locations of this protein?
Nucleus.
Protein: DUT_DECAR
Sequence: MHQIDVKILDNRLRETPPHYATPGSAGLDLRACIEAPLHVEPGQTTLVPTGMAIHLADPGLAAMILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSVWNRGHASFTLNPLDRIAQLIIVPVLQVGFNIVDDFDASHRGEGGFGSTGKA
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TTGB_PSEPT
Sequence: MSKFFIDRPIFAWVIALVIMLVGALSILKLPINQYPSIAPPAIAIAVTYPGASAQTVQDTVVQVIEQQLNGIDNLRYVSSESNSDGSMTITATFEQGTNPDTAQVQVQNKLNLATPLLPQEVQQQGIRVTKAVKNFLLVIGLVSEDGSMTKDDLANYIVSNMQDPISRTAGVGDFQVFGAQYAMRIWLDPAKLNKFQLTPVDVKTAVAAQNVQVSSGQLGGLPALPGTQLNATIIGKTRLQTAEQFESILLKVNKDGSQVRLGDVAQVGLGGENYAVSAQFNGKPASGLAVKLATGANALDTAKALRETIKGLEPFFPPGVKAVFPYDTTPVVTESISGVIHTLIEAVVLVFLVMYLFLQNFRATIITTMTVPVVLLGTFGILAAAGFSINTLTMFAMVLAIGLLVDDAIVVVENVERVMSEEGLPPKEATKRSMEQIQGALVGIALVLSAVLLPMAFFGGSTGVIYRQFSITIVSAMGLSVLVALIFTPALCATMLKPLKKGEHHTAKGGFFGWFNRNFDRSVNGYERSVGTILRNKVPFLLAYALIVVGMIWLFARIPTAFLPEEDQGVLFAQVQTPAGSSAERTQVVVDQMREYLLKDEADTVSSVFTVNGFNFAGRGQSSGMAFIMLKPWDERSKENSVFALAQRAQQHFFTFRDAMVFAFAPPAVLELGNATGFDVFLQDRGGVGHAKLMEARNQFLAKAAQSKILSAVRPNGLNDEPQYQLTIDDERASALGVTIADINNTLSIALGASYVNDFIDRGRVKKVYIQGEPSARMSPEDLQKWYVRNGAGEMVPFSSFAKGEWTYGSPKLSRYNGVEAMEILGAPAPGYSTGEAMAEVERIAGELPSGIGFSWTGMSYEEKLSGSQMPALFALSVLFVFLCLAALYESWSIPIAVVLVVPLGIIGALIATSLRGLSNDVYFLVGLLTTIGLAAKNAILIVEFAKELHEQGRSLYDAAIEACRMRLRPIIMTSLAFILGVVPLTIASGAGAGSQHAIGTGVIGGMISATVLAIFWVPLFFVAVSSLFGSKEPEKDVTPENPRYEAGQ
What is the function of this protein?
The inner membrane transporter component of a constitutive organic solvent efflux system.  Involved in export of toluene, styrene, m-xylene, propylbenzene and ethylbenzene.  Also exports AMP and the antibiotics carbenicillin, nalidixic acid, chloramphenicol and tetracycline.
What are the official names of this protein?
Toluene efflux pump membrane transporter TtgB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATA_STRP6
Sequence: MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRRDQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDFLIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLVAIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVIDTFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPELIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSRWAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVSPPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQQSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFDSVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFNEIMEGTAQVRDRIARSKFIPEENLEQIKGLTQKVTKEIHHVLAKGGI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RUTA_ECOLC
Sequence: MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPVLTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: IL1RA_HORSE
Sequence: MEIRRRSVRHLISLLLFLFYSETACHPLGKRPCKMQAFRIWDVNQKTFYMRNNQLVAGYLQESNTKLQEKIDVVPIEPDALFLGLHGRKLCLACVKSGDEIRFQLEAVNITDLSKNKEENKRFTFIRSNSGPTTSFESAACPGWFLCTAQEADRPVSLTNKPKESFMVTKFYLQEDQ
What is the function of this protein?
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A.  Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
What are the official names of this protein?
Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, IL1 inhibitor.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: 3DHQ_BOTFB
Sequence: MAVKKILLLNGPNLNLLGTREPHIYGYDTLASIESSLTTYLSSLTPSVTLLSFQTNWEGALIDRIHEARTDGTDAIVINPGAFTHYSIALRDALTGVDIPFVEVHISNVHKREEFRHKSFLSDKAEAVICGLGVYGYRAAVEWCVGYLKEKPKA
What is the function of this protein?
Is involved in the catabolism of quinate.  Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
What are the official names of this protein?
Catabolic 3-dehydroquinase, cDHQase, 3-dehydroquinate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: SYI_VIBPA
Sequence: MSEYKDTLNLPETGFPMRGNLANREPEMLERWYKEDLYGEIRKAKKGKKSFVLHDGPPYANGDIHIGHALNKILKDIIIKSKTLSGFDAPYIPGWDCHGLPIELMVEKKVGKPGQKVTAAEFREKCREYAAGQVEGQKESFKRLGIMGEWDKPYRTMDFATEANIIRALGKIASNGHLLKGFKPVHWCTDCGSALAEAEVEYKDKVSPSIDVRFKTADEAALLSKFELTEGHEGKGDVSIVIWTTTPWTLPANRAVCLRDDLEYVLIQVEGDNPERIIVAAELAKDVMDRAGIEHFHNLGFAKGADLELSQFQHPFYDFTVPAILGDHVTTDSGTGVVHTAPGHGQEDFAVGQKYNLEVANPVGSNGVYLPDTELFAGQHVFKANDAVVETLKEKGALLHHHAYEHSYPHCWRHKTPIIFRATPQWFVSMDQAGLRAKALESIKGVQWMPEWGQSRIEGMIEGRPEWCISRQRTWGVPIALFVHKETAELHPNTLELIEKVAKLVEEKGIQAWWDVDAAELLGDEAEQYEKVLDTLDVWFDSGVTHFSVVDAREEYNGNSADLYLEGSDQHRGWFQSSLISSIAMKGVAPYKQVLTHGFVVDGHGRKMSKSIGNVVAPKDVTNKLGADILRLWVASTDYTGEVAVSDEILKRSADAYRRIRNTARFFLANLNGFNPATDIVPAEEMVALDRWAVGRALAAQEEIIKAYDEYNIHAVTQRLMQFCSIEMGSFYLDVIKDRQYTAKQGGHAQRSCQTALYYIVEALVRWMAPIMSFTADEIWNEMPGEREKFVFTGEWFDGLFGLAEGEELNNEFWTEIQKVRGAVNKLLEAARAEKTIGGALQAELTLFADDALAAKINKLEDELRFVLLTSAAAVKPLSEKSDAAQATDIEGLFVEVKATEAEKCDRCWHHTPDVGTIAGHEKICGRCVSNVDGKGEVRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_SALRD
Sequence: MAQSSTQQRGRTPLMRQYYKIKERHPKAILLFRMGDFYESFDDDAKTVSRLLGITLTERNNGDADDVPMAGFPHHALDSHLPKLIRSGLRVAICEQVEDADDSSGKVVDRDVVEVVTPGVSFHDQLLNPKQSNFLAALHFGTGRDKDRIGFSFIDATTGEFSVTEAGLDQLQDLIQTVAPSEVIVDKRKTERLQQHLREVPFTVTEQEDWVFKYDFAYQTLLEHFETHSLKGFGVDDMDLGVVASGAALHYLGETQKGALPHVRKIKRYSKDEHIALDPETKRNLELVQSIQDDGHEGTLVSILDETETPMGGRRLRAWLVRPLRDVGRIRHRLDAVEACVDDRTLRDDLREELNQMGDLERLAGKVATGRAAPGDLIAIKHTLRRLPNVLGLLTDADSDALGAIEDDLRSCPEMVDRIQSALVDDPPAKISEGGLIRDGYSEELDELRTIAQEGKDWVANLETEESERTDIPSLKVGFNKVFGYYIEVTNTHADKVPEDYIRKQTLVDSERYVTPELKEMEEKILTAEEKIETLEQELFNELRSQIAQQTGILQENAELLAHLDCFAGLAEVAEQHDYTRPSVDDGLTIDIEEGRHPVVEQTLPPGDPFIPNDMALDPDDEQVLIITGPNMAGKSVALRQVGLIVLLAQVGSFVPAEAAQIGVVDRIFTRVGASDNLAAGESTFLVEMNEAANILNNATARSLILFDEVGRGTSTFDGLSIAWAIVEYLHERPEVAARTLFATHYHELNAMADRLERVHNYRIQVSEHEGEIVFLRKLIPGGADHSYGIEVAKMAGLPDAVIARAREVLQNLESQHLEVGADEADGAPSEDPPSEDPPSGDGVRAKKGEADAVPDLEDSQANQMHLFGQPDPAAEEIKEMLGEIDPNRITPVEALMKLAEMKETLAD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FLGG_ECO57
Sequence: MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGFFQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVTQQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGYVETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL
What are the official names of this protein?
Flagellar basal-body rod protein FlgG, Distal rod protein.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: FOXO_DROWI
Sequence: MDGFAQDWPSLTHTTDNVLTMDQLGGVSGAVGDLPGDVGFEPQTRARSNTWPCPHPEPFVEPADELDSTKASNQQLAAGDSQQTIQSANAAKKNSARRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGFQLSPDFRQRASSNASSCGRLSPIRALDLEPEWGFTVDYQNTTLTQAQSQVLDQLAGSIADELKLHPDMLQQQGFSAASGLPTQPPPPPYPAPQQQQQQQPQQQQAYTLNGGPPGGYASLQPQPQCLIHRSLNCSCLHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVIDGSGDNGSLLVQQQRQQQQQQQQQQQLGSNLEGQCLEVLNNEAQPIDEFNLENFPVENLECNMEELLQQEMSYDGLLDINIPLAAVSTNAPLVNLINNSSTTISSSSNIGCSTTTSSSSLSASAQLNQLQAQLQQQHQQQQQQQQQQQQQQLQQQQQQLLLNNNNNNNNSLELATQTASANLNARVQYSQPSVVTSPPSWVH
What is the function of this protein?
Transcription factor involved in the regulation of the insulin signaling pathway.  Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR.  Involved in negative regulation of the cell cycle, modulating cell growth and proliferation.  In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.  Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging.  Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis (By similarity).
What are the official names of this protein?
Forkhead box protein O.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation (By similarity).
Protein: IL5_RAT
Sequence: MRMLLCLNVLTLSCVWAIAMEIPMSTVVKETLIQLSTHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEILFQNLSLIKKYIDGQKEKCGEERRKTRHFLDYLQEFLGVMSTEWAMEV
What is the function of this protein?
Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:10446387).  Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity).  Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB.  Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity).
What are the official names of this protein?
Interleukin-5, IL-5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF.
What is the protein family that this protein belongs to?
Belongs to the IL-5 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXH_SALDC
Sequence: MSDNDQLQQIAHLRREYTKGGLRRRDLPAEPLTLFERWLGQACDARLADPTAMVVATVDDKGQPYQRIVLLKHYDEKGLVFYTNLGSRKAHQIEHNPRISLLFPWHMLERQVMVTGKAERLSTLEVVRYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSIEQMEFWQGGEHRLHDRFLYQRDDGAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: H1L_MYTCA
Sequence: PSPSRRSRSRSRSRSKSPKRSPAKKARKTPKKRRATGGAKKPSTLSMIVAAIQAMKNRKGSSVQAIRKYILANNKGINTSRLGSAMKLAFAKGLKSGVLVRPKTSAGASGATGSFRVGKAPSSPKKKAKKAKSPKKKSSKKSSNKSNN
What is the function of this protein?
Linker histones are implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa.
What are the official names of this protein?
Sperm-specific protein PHI-2B, PL-II*, Sperm-specific linker histone H1-like protein.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: AATM_SCHPO
Sequence: MLARNLRCLHPNTFASLKTNVSYHGVKCLASQSKRGFKVWADVPMGPPDPIFGITEAYKKDGDVKKMNLGAGTYRDDAGKPYVLPSVRQAETELLSQKLDKEYAPITGIPSFRVQATKLAYGDVYESIKDRLVSAQSISGTGALCIAANFLASFYPSKTIYVSDPTWGNHKNVFSRAGLTVKSYKYYDPATRGLDIKGMLSDLTSAPDGSIILLHACAHNPTGVDPTKAQWDDILKTMQKKNHFALLDMAYQGFASGDFARDAYATRLFASSNVPMLLCQSFAKNMGLYGERAGCFSILANDAEEAARIESQTKILIRALYSNPPVNGARIANHILSNPALREQWAGEVVGMSERLKSMRKALRNILEKDLKNKHSWKHITDQIGMFCYTGLNPQQVDVLAKQYHIYLTKNGRISISGLNTSNVRYFAEAINAVTSN
What is the function of this protein?
Plays a key role in amino acid metabolism.  Important for metabolite exchange between mitochondria and cytosol (By similarity).
What are the official names of this protein?
Aspartate aminotransferase, mitochondrial, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RAD17_YEAST
Sequence: MRINSELANKFSASTVHLEHITTALSCLTPFGSKDDVLIFIDADGLSFVRENNHVIKIQLLLSRELFMSYSYRNETEDHMKLCVKINHILDSVSVMNRNSDDIVECTLSYDGHGSPFVLIFEDSFISERVEYSTYLIKDFDTNGLELDRERISFEAIIKGEALHSALKDLKEIGCKECYVYAKTEANDENVFALISKSQLGFSKIKLPSNRSILEKLQVFDGDSTTVIDGFAVIGFFDFTSFDKIRKSTKIASKVLFRMDVHGVLSVNILSQTDDVIITDTTRPSNNRPGSIRQLQLPKDYPGIVIEVCMLEKESIDEAAQTEIELLMETNELGNRNSFKKSTIRKRYGTDKGNETSNDNLLQLNGKKIKLPSEEENNKNRESEDEENHCKYPTKDIPIFF
What is the function of this protein?
Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.  Associates with sites of DNA damage and modulates the MEC1 signaling pathway and the activation of RAD53 in response to DNA damage at phase G1.  The complex also physically regulates DNA polymerase zeta-dependent mutagenesis by controlling the access of polymerase zeta to damaged DNA.  Contrary to its human counterpart, the 9-1-1 complex, the checkpoint clamp complex shows no detectable exonuclease activity.
What are the official names of this protein?
DNA damage checkpoint control protein RAD17, DNA repair exonuclease RAD17.
What is the protein family that this protein belongs to?
Belongs to the rad1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YIDC_HAEIN
Sequence: MDSRRSLLVLALIFISFLVYQQWQLDKNPPVQTEQTTSITATSDVPASSPSNSQAIADSQTRGRIITLENDVFRLKIDTLGGDVISSELLKYDAELDSKTPFELLKDTKEHIYIAQSGLIGKNGIDTRSGRAQYQIEGDNFKLAEGQESLSVPLLFEKDGVTYQKIFVLKRGSYDLGVDYKIDNQSGQAIEVEPYGQLKHSIVESSGNVAMPTYTGGAYSSSETNYKKYSFSDMQDNNLSIDTKAGWVAVLQHYFVSAWIPNQDVNNQLYTITDSKNNVASIGYRGSVVTIPAGSQETITSSLWTGPKLQNQMATVANNLDLTVDYGWAWFIAKPLFWLLTFIQGIVSNWGLAIICVTIVVKAILYPLTKAQYTSMAKMRILQPKMQEMRERFGDDRQRMSQEMMKLYKEEKVNPLGGCLPILLQMPIFIALYWTFLEAVELRHAPFFGWIQDLSAQDPYYILPILMGISMFLLQKMSPTPVTDPTQQKVMNFMPLVFMFFFLWFPSGLVLYWLVSNLITIAQQQLIYRGLEKKGLHSRKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS15_LEIXX
Sequence: MALDAETKKSIIDEYATHPGDTGSPEVQVAILTQRIRDLTEHLKEHKHDHHSRRGLLLLVGQRRRLLGYLADIDISRYRALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: YQGF_PSEAB
Sequence: MASDKPLRLLLGFDYGTRQIGVAVGQAVTGQARELCVLKAQNGVPDWNRVEALIKEWQPDAIVVGLPLNMDGSPSEMSERAEKFGRRLNGRFNLPVFTHDERLTTYAAKGERLAQGQRDGYRERPVDALAAALLLEGWLAEHPD
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDCG_KLEPN
Sequence: MSATPRPHDLVWLNHASALEDIAEPWVAQQWRAALPVVVRRDVDDQARVPVGVRGMKREQRAAGWVQARNIVRSVTPEMLVDREVLLHSPFVSQPPVQGAIALTLHRWPWGWGVTGSTGYALATEIPVLHAASDLDLLIRAPQPLDREALLEWQTRVAQLPCRADTQVETPYGAFALNEWLRDGRALLKTSRGARLTATPWHREE
What is the function of this protein?
Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].
What are the official names of this protein?
Phosphoribosyl-dephospho-CoA transferase, Malonate decarboxylase holo-[acyl-carrier-protein] synthase, Holo-ACP synthase.
What is the protein family that this protein belongs to?
Belongs to the MdcG family.
Protein: H2AZ_RAT
Sequence: MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV
What is the function of this protein?
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  May be involved in the formation of constitutive heterochromatin.  May be required for chromosome segregation during cell division (By similarity).
What are the official names of this protein?
Histone H2A.Z, H2A/z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.