PharMolix/UniProtQA huggingface dataset:
Protein: MRAZ_DICT6
Sequence: MFVGEYYHSLDEKGRLIIPNDFRQLLGETFYLTRGFERCLNIYTITDWNNFSQIISSFSPTDNLMRKLCRFWFSGSIQVTTDKLGRILIPSFLIEYAELSKEVVIIGAGKHIEIWAKEKWEEFNKEENILENMNEINSKVAELWKK
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CAMT1_ARATH
Sequence: MANEIPTKGILKSEALKQYIMETSAYPREHELLKELRKATVQKYGNLSEMEVPVDEGHFLSMLVKIMNAKNTIEIGVFTGYSLLTTALALPEDGRITAIDIDKEAYEVGLEFIKKAGVDHKINFIHSDGLKALDQLVNDKCEFDFAFADADKSSYVNFHERLLKLVKVGGIIAFDNTLWFGFVAEDEDGVPEHMREYRAALIEFNKKLALDPRVEVSQISIGDGITLCRRLV
What is the function of this protein?
Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA.  Plays a role in the synthesis of feruloylated polysaccharides.  Involved in the reinforcement of the plant cell wall.  Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers (By similarity).
What are the official names of this protein?
Putative caffeoyl-CoA O-methyltransferase At1g67980, Trans-caffeoyl-CoA 3-O-methyltransferase, CCoAMT, CCoAOMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
Protein: RAPZ_SHIF8
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: RS15_METM5
Sequence: MARLHSGKRGSSGSTRPLRTEVPEWVSMSAEEIEAKIVEMAKDGKQSAIIGNILRDMYGVPNVKLITGKSVSSIMKEAGFYAEVPEDLFNLMKKAINLRNHLENNPRDTHSTVGLKLIESKIRRLVKYYRGTKVLPAKWRYSPETARLLVE
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ACNA_RICFE
Sequence: MSKVHNSEYIKELSVDNTSYKIYDINKAASDIELPLKKLPYSLRVLFENVLRSNGSKQNLLVFKEWLKTKESDAEIDFMPARVLMQDFTGVPAIVDLAAMRDAMKKIGGDPLKINPLIPVDLVIDHSVSVDSYAAKDSFDKNVQMEMKRNIERYQFLKWGQQAFNNFKVVPPGTGICHQVNLEYLAKVVWHKDGLAYPDSLVGTDSHTTMVNGLSVLGWGVGGIEAEAAMLGQPLTMILPEVIGVKLTGKLTGIATATDLVLTVTEMLRKKKVVGKFVEFFGEGLKNLTIADRATISNMSPEYGATCGFFPIDQETIKYLELTGREKTQIKLVEKYANEQNLWYDFEHEAEYTEILELDLSMVHSSLAGPRRPQDRVDLNDVANNFKHELPNFGIENKDIDKKYAVANQNYEIGNGDVVIAAITSCTNTSNPSVMIGAALLAKKALEHGLKVKPWVKTSLAPGSKVVTEYLKLSGLDKYLDELGFNLVGYGCTTCIGNSGPLNPEIEETINKNGLVVASVLSGNRNFEGRINPLTKASYLGSPILVVAYALSGTLNIDLNNQPIGKNIYLKDIWPSKEEIDEVIANSINSSMFIEKYSDIFSGTKEWKDLQITTSSTYNWNKNSTYINNPPYFEDIGSKNNIKDIKSAKILAIFGDSITTDHISPAGSISKTSPAAKYLTDNHIEPLDFNSYGSRRGNHEVMMRGTFANIRIKNEMCKGVEGGFTINQLSSTQQTIYDAAMDYKANDVPVVIFAGKEYGSGSSRDWAAKGPQLLGVKAVIAESFERIHRSNLVGMGILPLTFTGNNTRLDLKLDGSETIDIIGLSEQIKPYNPVKCMIKKQTGETRTIDLILQIFTDNEINYIKHGSIMHFVVENLKG
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The apo form of AcnA functions as a RNA-binding regulatory protein.
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, Iron-responsive protein-like, IRP-like, Probable 2-methyl-cis-aconitate hydratase, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: ENO_ANADE
Sequence: MTEIINVTAREILDSRGNPTVEVEVAVGTGDVGRAAVPSGASTGEHEALELRDGDKARYLGKGVRKAVANVIDEIAPAVVGLDASDQAALDARMIALDGTPTKSKLGANAILGVSLAAAKAAATAHGLPLYRYVGGAGARTLPVPLMNILNGGAHADSNVDIQEFMVVPLGLPTFAEALRCGAEIFHALKKVLKGKGAATGVGDEGGYAPSLASNEEALAVIMEAIGQAGYEPGKQVALALDCAASEFYDKKAGKYELEGEGKSFDGKGLVEYYAQLAAKYPIVSIEDGCDEDDWATWKLLTERLGGKLQLVGDDLFVTNVTRLARGIEQGVTNSILVKVNQIGSLTETLEAVRMAHRAGYTTVMSHRSGETEDTTIADLAVACDCGQIKTGSASRTDRIAKYNQLLRIEEELGTSGRYAGRSAFKALR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: VL2_HPV5B
Sequence: MARAKRVKRDSVTHIYQTCKQAGTCPPDVINKVEQTTVADNILKYGSAGVFFGGLGISTGRGTGGATGYVPLGEGPGVRVGGTPTVVRPSLVPETVGPVDILPIDTVNPVEPTASSVVPLTESTGADLLPGEVETIAEIHPVPEGPSVDTPVVTTSTGSSAVLEVAPEPIPPTRVRVSRTHYHNPSFQIITESTPAQGESSLADHVLVTSGSGGQQIGGDITDIIELEEIPSRYTFEIEEPTPPRRSSTPLPRNQSVGRRRGFSLTNRRLVQQVQVDNPLFLTQPSKLVRFAFDNPVFEEEVTNIFENDLDVFEEPPDRDFLDVRELRRPQYSTTPAGYVRVSRLGTRATIRTRSGAQIGSQVHFYRDLSSINTEDPIELQLLGQHSGDATIVQGPVESTFIDMDISENPLSESIEAYSHDLLLDEAVEDFSGSQLVIGNRRSTNSYTVPRFETTRNGSYYTQDTKGYYVAYPESRNNAEIIYPTPDIPVVIIHTHDNTGDFYLHPSLRRRKRKRKYL
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: PDRP_BRASB
Sequence: MPTTGNYFHLHLVSDSTGETLITVARAVAAQYANVTPVEHVYPLVRSQKQLDRVLDEIEEAPGIVLFTLLEKDLVSRLEAKCQQINIPSLSIIGPVMQLFEAYLGASTAGRVGAQHVLNAEYFARIDALNYTMLHDDGQMVDGLEDADVVLVGVSRTSKTPTSIYLANRGVRTANVPLVPGIPIPHQLETLKKPLVVSLHATPERLIQVRQNRLLSMGAESGNETYVDKQSVTDEVAYARKLSARFNWVMLDVTRRSIEETAAAILKLYTDRQRQRLPE
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RPOB_METPP
Sequence: MAQATPYSYTERKRIRKSFGKRENVLGVPYLLTMQKDSYVAFLQKDVPPQKRKPEGLQAAFLSAFPIVSHNGFVEMKYIEFNMAKPAFDTRECQQRGLTYAAAVRAKLQMIIYDRETSTSQSKVVKEIKEQEVYMGEVPLMTDYGSFIVNGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKAIGLNPEQILANFFVFDNFRLMDSGAQMEFVADRLRGEIARFDLTDKAGAVIVEKDKRITARHTRALEASGTSFISVPEDFLVGRVLAKNMVDADTGEIIAKANDELTDSLLKKLRTAGIKDIQCLYTNELDMGAYISQTLASDETADELAARVAIYRMMRPGEPPTEDAVQALFNRLFYSEDTYDLSRVGRMKFNARVGRDTAEGRMVLANDDILDVVKILVELRNGRGEVDDIDHLGNRRVRCVGELAENQYRSGLARIEKAVKERLGQAETEALMPHDLINSKPISAALKEFFGASQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAQLNEYGFLETPYRRVIDSKVTDQIDYLSAIEEGKYVIAQANAGLDKDGKLIDELVSARESGESVLTSPERIQYMDVAPTQIVSVAASLVPFLEHDDANRALMGANMQRQAVPVLRPEKAFVGTGVERVSAVDSGTVVTAKRGGVVDYIDTNRIVIRVNDAETVAGEVGVDIYNLIKYQRSNQNTNIHQRPIVQRGDQVGAGDVIADGASTDIGELALGQNMLVAFMPWNGYNFEDSILISERVVADDRYTSIHIEELVVMARDTKLGSEEITRDIPNLSEQQLGRLDESGIVYIGAEVNPGDVLVGKVTPKGETTLTPEEKLLRAIFGEKASDVKDTSLRVDQGTNGTVIDVQVFTREGIQRDKRAQQIIDDELKRFRLDLNDQLRIVEADAFDRIEKLLAGKTANGGPNKLAKGTPIDKAYLASVDKYHWFDIRPADDDIANQLESIKNSLEQTRHSFDLAFEEKRKKLTQGDELPAGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPYMADGTPCDIVLNPLGVPSRMNVGQVLEVHLGWAAKGIGQRIGDLLQQEAKIADVRKFLDELYNKSGGKSEGLNGLSDAEITEMATNLAQGVPFATPVFDGATEEEIRAMMHLAYPDEIAAAKGLNATRTQATLHDGRTGDAFERPVTVGYMHVLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYESIVKGEHAIEAGMPESFNVLVKEIRSLGIDIELERN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SYY_CORJK
Sequence: MSDNMNIIDELQWRGLINQSTDLEALKEATQNPITLYCGFDPTGSSLHAGHLVPLIMLKRFQQFGHRPITLAGGATGMIGDPRDVGERSMLTEEQIGENMVAIKKQLEAFVDFTEDSDVDSPAVMVNNADWISQMNVIEYLRDVGKNFSLNTMLDRDTVKRRLESDGISYTEFSYMLLQANDYVHLHNEFDCVLQIGGGDQWGNIVSGVDLNRRVNGAKVHGLTVPLVTDAEGNKFGKSTGGGKLWLDPQLTSPYSWYQYFINAGDSVVIDYLRWFTFLSQEEIAELERKVAEEPFKREAQRVLAREMTTLVHGAAATEAVELAAQALFGKAELQDLDEPTLASALQETEVAEVGADATILDLLVESGLEKSKGAARRTVGEGGAYVNNQRIEDIEWSPSAEELLHGSWLVLRKGKKRFAGARVGASS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSF_RHOPA
Sequence: MIPMEGGAQGALRTRPDIKGSVDSLNIAKQDTILTPRFYTTDYAAMDKLDVSLVRAEWTAMMNELRADYNKSHFKKTDEFVNSDLDKLPPELRAEFKDFLVSSLTAEFSGCVLYAEIKKRIKNPEIRELFGLLSRDEARHAGFINEILKDHGIGVDLSFLTKVKKYTYFRPKFIFYATYLSEKIGYARYITIYRQMERHPERRFHPIFKWFERWCNDEFRHGEAFALLMRADPSLLSGVNKLWIRFFLLAVFSTMYVRDHMRPAFYEALGVDATDYGMQVFRITTEISKQVFPVTINLDDPRFLQNLERLRIAAEKIDRSHSQGLLGKLKRPFYAASAALAFGRLFLLPAKRNELPRVIGLRPAW
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: KRA44_HUMAN
Sequence: MVNSCCGSVCSDQGCGLENCCRPSYCQTTCCRTTCCRPSCCVSSCCRPQCCQTTCCRTTCCHPSCCVSSCCRPQCCQSVCCQPTCCRPQCCQTTCCRTTCCRPSCCRPQCCQSVCCQPTCCCPSYCVSSCCRPQCCQTTCCRTTCCRPSCCVSRCYRPHCGQSLCC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 4-4, Keratin-associated protein 4-13, Keratin-associated protein 4.13, Keratin-associated protein 4.4, Ultrahigh sulfur keratin-associated protein 4.13, Ultrahigh sulfur keratin-associated protein 4.4.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 4 family.
Protein: RPPH_PSESM
Sequence: MIDPDGFRPNVGIILTNDAGQVLWARRINQDAWQFPQGGINPQETPEDALYRELNEEVGLERHDVQILACTRGWLRYRLPQRLVRTHSQPLCIGQKQKWFLLRLISNEQRVRMDLTGKPEFDGWRWVSYWYPLGQVVTFKREVYRRALKELAPRLLSRD
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: DHRS3_BOVIN
Sequence: MVWKRLGALVVFPLQMIYLVVKAAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALPKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALIILKSILPQAALEEIHKFSGTYTCINTFKGRT
What is the function of this protein?
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
What are the official names of this protein?
Short-chain dehydrogenase/reductase 3, Retinal short-chain dehydrogenase/reductase 1, retSDR1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL30_GEOSE
Sequence: MAKKLAITLTRSVIGRPEDQRITVRTLGLRKMHQTVVHNDNPAIRGMINKVAHLVKVKEIEEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SERC_BURA4
Sequence: MRVFNFSAGPAALPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALADLRELLDVPASHRILFLQGGGIAENAIVPMNLLGSRKTADFVVTGSWSQKSFNEAKKYGTPHLAASGKTADGFTRAPARAEWQLSDDPAYVHLCTNETIDGVETFEIPDLGDVPLVADVSSHILSRPMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTVAANNSLYNTPPTYAIYIAGLVFQWLKRQGGLEAIEARNIEKAKLLYDTIDASGFYLNKVEPAVRSRMNVPFFLADETRNEDFLAGAKARGLLQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRGA
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIM1_YEAS1
Sequence: MSDEIVTNKSVTYVNNTTPVTITSSELDLRSCYQDDEVVIEVHAAALNPIDFITHQLCNSYIFGKYPKTYSRDYSGVIIKAGKDVDNRWKVGDKVNGMYSHIYGERGTLTHYLILNPAKDIPITHMVEVPKDENDPYDDFVYAAAWPLTFGTAFSTLYDFKKDWTSDSKVLVIGASTSVSYAFVHIAKNYFNIGTVVGICSKNSIERNKKLGYDYLVPYDEGSIVENVKKLKQIVLENDKFDMIFDSVGNHDFFPVIDQFLKPKAKNSFYVTIAGNNKANYKNISWRDFVSLSSILKAINPFKKYNWRFGHPYPPNNFIEVGNEMIKKGTYKPPIDSVYEFDQYKEAIDRLMSNRAKGKVVVKMK
What are the official names of this protein?
Protein YIM1.
What is the protein family that this protein belongs to?
Belongs to the YIM1 family.
What are the subcellular locations of this protein?
Lipid droplet. Mitochondrion.
Protein: DNLJ_PSE14
Sequence: MKAVETRILELRAELDEHNYRYHVLDEPSIPDVEYDRLFHELKALEAENPHLVTPDSPTQRVGSAALSAFTQVRHEMPMLSLGNAFEENDMLEFDRRVTEGLDLPAGDLFGAGSKVQYSCEPKLDGLAVSLLYRDGALVRGATRGDGTTGEDISVNVRTVRNIPLKLKGKGWPDVLEVRGEVFMSKAGFERLNASQLEIGGKTFANPRNAAAGSLRQLDSKITANRPLEFCCYGLGQTSAEIADTHIGVLETLKKWGMPVSHELKLANGVEECLDYYRDIGERRLTLSYEIDGVVFKVNNLAAQRELGFRAREPRWAIAHKFPAMEELTELLDVEFQVGRTGAVTPVARLKPVKVAGVMVANATLHNMDEVARLGLMIGDTVIIRRAGDVIPQVVQVVAERRPENARAVQVPQTCPVCGSHVERTQLIKRSKGKETVTEGAVYRCVGRLACGAQLKQAIIHYVSRRAMDIEGLGDKTIEQLVDEKLIGSPADLYKLKYEQIIDLEGFAEISSNKLLKAIADSRQPTLARFIYALGIPDVGEETAKVLARSLASLDRVKQALPEVLTYLPDVGLEVAYEIHSFFEDEHNRNVIDALLGECGLQLQDQGELGAEFAASTTLEGLIDKLHIPSVGPGAAQKLADRFGTLEAIISADWLDMRQTLPEKQAKSVRDFFDDSAHAERARAIEAQLKDFGMHWRSEKKTVEGLPLAGQTWVLTGSLERMSRDVAKEKLESLGAKVSGSVSAKTHTVVAGPGAGSKLTKANELGLTVLDEDALLKRLTELGVAVD
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: YQGF_XYLFT
Sequence: MPEASSPFPDGIVLGFDVGTRRIGVAVGSALGAGARAVAVIDVHGVAVDWNALDRVKRNWLPVGLVVGDPLTLEGHDQPIRKQAHAFACQLRERYRLPVVLVDERSSSVEAASRFAGARAAGYKRRRDADTLDAIAAAVILERWLADPMQATSLP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_NICSY
Sequence: MSPQTETKASVGFKAGVKEYKLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYRIERVVGEKDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFVEQDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAQEGNEIIREACKWSPELAAACEVWKEIVFNFAAVDVLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MED8_AEDAE
Sequence: MQREEKQMDMLLEAVLNRLNDLKHSIGAMIHRLETEYETINWPTFLDNFALISGHLTGLSKILSSEIGTPLRNLTVLPLLLTPERDEALLQLTEGRIPIFSHDLVPDYLRTKPDPGAESRMAAHEAKANNLQPDTAAKQVAQYNKVISHVWDIVSKAREEWDTEASSRPGIQQTSSLADTQALVAAVGVGNGLTMPVGPGGVPNAGIMIPPAIRQASPMSAVSPGAGPLGKMPSGIKTNIKSANQVHPYR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 8, Mediator complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SMG8_AEDAE
Sequence: MNPVESFVFPDIPKTIRDVLFKPDKQMIIVGVIGKSSNPTCNKLIGFNLLTTHPALTDSKCCEGRIKFYFENDGNVLYLHFETTFDQQVMAEQLAKAIDTGVQDNFVNFNSYVRSRFARMLLFAIQVCHMIVLVEPTSVFDTSYLSIFKSLKIIREKYVLKFLPKLLKASNVGNYMGKEARLCSPRFIFLFEGTCDIKPEDVEKLEALECAVEEDIYKMLRTEFIITNNSAMSLFSIPRSKKFVFFSSDSKAKSDPLLDSIDMLMEYLDKPAAGQQGDKDEEEFMNKLRPCAGYGMSAWSVGAGAPKTERERSVLTLIKKHVAEAFEHGFDDSVSKYRGRSHFAVPGFKSWFEGFKFLHKIFIENPDNQNYEPVDVDYKAYLENFHKVIDIDERFFADVCEHGMELAMVNYKEMLPHHYSGTFHEKKYQQARELFLRYARGPEVEKHELKLKDYCDSIWLNGKQQCEYPSLRGNPCALGKHKANDPMDHSSGVVFVSACNCGRTQGHREDPYTIRQANYEFYQLIAKSCSNCTLLERIKFPVFEPSSSDFRAAEFINKNLSNLMSLENSNRTPDTGTHPPMTNDHSPHLSGSQKSQDSASNLTFSIDDKEENETHAKNYASQGDADEALEQENLNEIVIKVGEHADQTDKEKAILRQPSTTEYLPGMLHATSPIGLLPQFPSWSLVCLGPSSIYTHNSGLPEHIQSGFLSGSNFLLPWDVSVRLEHAQSWAASYEKIRNRKKNVSQSKSSDSSNNFTLKIFIGIEYECLRGHRFIMSGPDTVLRGGSGIVRDSGSKVVFNDMPIYFPCLCRNSNVAQLMRVHIVTPKAPVNVILEPKAKIFQNNMQSNFTFTTGQPEPIKLTQSAYWILRLPFVYEGDEGPLMPPSEVNASNAAMHGILLAGMYGIKESEISEELL
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Probable component of kinase complex containing SMG1 and recruited to stalled ribosomes (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG8, Protein smg-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG8 family.
Protein: TSAD_BAUCH
Sequence: MRVLGIETSCDDTGVAIYDDQHGLLTNQIYSQAKIHANYGGVVPELASRDHLRKIVPLIQAALSEARLQAKNIDGVAYTAGPGLISSLMVGATVGCALAYAWKVPNIAVHHMEGHLLAPMLEINPPSFPFVALLVSGAHTQLIAVTKMGKYQLLGQSVDDAVGEAFDKTAKLLGLDYPGGPMLSKIAQQGIAGRYKFPRPMTERPGLNFSFAGLKTFAANTINIAASDAQTHADIARAFEDAVVDTLMIKCQRALDQTGFKRLVMAGGVSANQTLRNRMKKMVEQRGEEIFYARPELCTDNGAMIAYVGSVRFASLVLPQSQLAVIVRPRWPLEELTTISR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNB_UNCRE
Sequence: MTDQREEPQGSNDHLVRSSDPEHPANLIPELCKKFYTLGWVTGTGGGTSIRRDGHIFIAPSGVQKEMIKPEDIFVLSYPTPKYPPSARQYIRKPQELKPSACTPLFLAAFDRGAGCSIHTHSQWAVLVTLLVEREKGKNGCFEINNIEQIKGIPKGKGKGMLGFFDTLRIPIIENTAFEEDLTESLEKAMDEYPDTYAVLVRRHGIYVWGDTVAKAKTQCESLDYLFQLAVEMHKLGLPWVQ
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.