PharMolix/UniProtQA huggingface dataset:
Protein: F15_FOWPN
Sequence: MNVSRLEELISMNPFSDMENIVINEKEKCILGNRCFVKLSEVYNMPMCCIDTNQCLTMNRFKFSLNELLYTPFYYKQLQYQYLTPQFIFRCIQEANENNMSCYYCYTKKKEHNGLNIDIFIPTANSKSYIVIGLRIKDFWKQSFKVNK
What are the official names of this protein?
Protein F15.
What is the protein family that this protein belongs to?
Belongs to the poxviridae F15 protein family.
Protein: MURA_PSEMY
Sequence: MDKLIITGGVRLDGEIRISGAKNSALPILAATLLGDEPVTICNLPHLHDITTMIELFGRMGVEPVIDEKLSVEVDARSIKTLVAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAQIDVEGGYIKAKAPEGGLRGAHFFFDVVSVTGTENIMMAATLAKGRSVLENAAREPEVVDLANCLIAMGAKIQGAGTDTIIIDGVERLHGARFNVMPDRIETGTYLVAAAVTGGRVKVKDADPSTLEAVLAKLQEAGAEITTGPDWIELDMKGKRPKAVNLRTAPYPAFPTDMQAQFIALNAVAEGTGTVIETVFENRFMHVYEMLRMGANILVEGNTAIVTGVEKLKGAPVMATDLRASASLVLAALMAEGDTLIDRIYHIDRGYECIEEKLQLLGAKIRRVPG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_TRYBB
Sequence: MKYVGSIDQGTTSTRFIIFDERQRPVSVHQVPHTQHTPHPGWLEHDPMEIFRSACKCMSVAIAKLRQKDASFRKIEAIGITNQRETTVAWDRVTKEPLCYAPVWNDLRTYDITKKVTAELGGGDSMFASKITGLPVSTYFAAFKMRWMLENVPAVADACRRGTLCFGTIDTWLMYKLSGGKAFVTDVTNASRTFLMDLRTRKWSPELCEKLKIPMETLPEIRSNSELFGYVETDECGVAAALNERTPIMGSIGDQQSALFGNMCFEKGEAKNTYGTGCFLLMNVGEEARFSKHGLLSTVGFQVGRDGPCYYALEGAIACAGATVEWMRRNMNLFSHITECEKLARSVPGTQGIVFVPAFSGLLAPYWDPSARGTIVGMTLKTTRAHVIRAALQAIALQLNDVVGSMKRDAGLNLSSLRVDGGLSKNGLLMEIQASLLGVDILVPSMHETTALGAALCAGLAAGVWTSLEEVKAVSRRENSWKTVSPSGSAMEREAMIAEWREALKRTKWAKL
What is the function of this protein?
Catalyzes the phosphorylation of glycerol using ATP (PubMed:10759857, PubMed:11154065).  Under anoxic conditions, when glycerol 3-phosphate accumulates in the glycosome, it catalyzes the reverse reaction, maintaining the ATP balance (PubMed:10759857, PubMed:11154065).  Key enzyme for the survival of bloodstream forms under anoxic conditions (PubMed:11154065).
What are the official names of this protein?
Glycerol kinase, glycosomal, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Glycosome.
Protein: THII_LIGS1
Sequence: MQYTEIMVRYGELSTKGKNRKNFIDRLGFNVRESLHSFENLVIKAHRDRMHIQLHGEDYEAVMKRLKQVFGIQNFSPSIKVERDIEKVKVTAVEMVKEKFKEGMTFKINTRRSDHNYQYDTNEMNDILGSHILREVPGIKVKMKNPDMTLRCEVRADGIYLSHEKIDGAGGLPVGTAGKAMLMLSGGIDSPVAGYLAMKRGVDIEMVHFFSPPYTSEQALNKAKDLTAKLTPYVGKIRFIQVPFTEIQETVKEKVPSGYLMTIQRRFMLRLTEAIAQRRKGLAIFNGEALGQVASQTLESMAAINDVTTMPILRPVVSMDKNEIIKIAQDIDTFDLSIMPFEDCCTIFAPPAPKTKPRIDKARYYEERLDVDALVQRALDGIEITEIKIGDTFLNQEKKVFAELL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_NEOSM
Sequence: MAKVWQFSEAEELFHLPFLDLLYSAQHVHRENFPHNEVQLAMLLSVKTGGCPENCSYCPQSAHYDTGLRKEPVMHVEKVLEAAKRAVELGATRFCIGAAWRGPRGKDLDIVCEMISRIKKLGLETCASLGLLSYEQAVSLKAAGLDFYNHNIDTSQEYYSKIITTRRFSDRIETLENVAKAGLKICSGGILGMGESNEDRIKMLVELSHLSFPPESIPINKLIPIPGTPLAEKNAVDPLDFVRIIALARIMFPKSYVRLSAGRESMSDELQTLCFIAGANSIFYGEKLLTSANSDPESDEKLLLKLGLLREKSKTAVDCSINLGS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: DIR25_ARATH
Sequence: MAGCKVLFFLILALAITFVSAARLLDEEEDIGLVPLPTTSPGPLPTVGLGPFPTANSGPATGIASGTGSASGGLGSLGTNTGPGPLSTTGSSLLPVASSGTLPVTGPGPLPTSSGLLPGASSGNLPGSGSGPLPTVGSGAAATGLGAGAGSVIGGSVPDNTLVFFMHDILGGSNPTARAVTGVVANAALSGQIPFAKPNGANLPVSNGVPSDNNNNGILNNNNVPLLVGLGGTTSNILQNNGNNMLNGLPVANGGQLPSGSSLQMLMFGTLTVMDNELTEGHELGSGLLGKAQGFYVASALDGTSQTMAFTAMFESGGYEDSISFFGVHRTAASESHLGVMGGTGKYVNARGFAIVKTFTGSSGTQQQQPHQFTDGLETVLECTVYLSY
What is the function of this protein?
Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.
What are the official names of this protein?
Dirigent protein 25, AtDIR25.
What is the protein family that this protein belongs to?
Belongs to the plant dirigent protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: IF1_STRSV
Sequence: MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNYIRILAGDRVTVEMSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRDX5_VULVU
Sequence: APIKVGDAIPXVXVFE
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
What are the official names of this protein?
Peroxiredoxin-5, Autoantigenic sperm protein 5, Peroxiredoxin V, Prx-V, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin 5, fSP5.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx5 subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm. Peroxisome matrix.
Protein: G6PI1_RHOJR
Sequence: MSSDITGTAAWQKLRDHHAQIQSVHLRELFEKDPARGQELTVTAGDLYIDYSKHRIDRDTLGLLLELARSADLEARRDAMFAGEHINTSEDRAVLHTALRLPADASLVVDGQDVVADVHEVLDRMGDFTDRVRSGEWRGATGERIKTVVNIGIGGSDLGPVMVYRALRHYADAGISVRFISNVDPADLVRSLQGLDPATTLFIVASKTFSTLETLTNATAARRWLLGGLGLGNEAVAKHFVAVSTHADRVAEFGIDTANMFGFWDWVGGRYSVDSAIGLSVMAAIGKERFAEFLAGFHAVDEHFRTAPLEENAPVLLGLIGLWYSNFFGAESRAVLPYSNDLVRFAAYLQQLTMESNGKSVRADGTPVPTSTGEIFWGEPGTNGQHAFYQLLHQGTRLVPSDFIGFGEPTDDLPTADGTGSMHDLLMSNFFAQTKVLAFGKTAEEIAAEGTPEHLVPHKVMPGNRPSTTILAPKLTPSVIGQLIALYEHQVFVEGVVWGIDSFDQWGVELGKTQAVELQPVLTAAEEPAAQSDSSTDSLVRWYRRQRGRA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase 1, GPI 1, Phosphoglucose isomerase 1, PGI 1, Phosphohexose isomerase 1, PHI 1.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_CHLPN
Sequence: MKIDILSLFPGYFDGPLQTSILGRAIKQRLLDVQLTNLRDFGLGKWKQVDDTPFSGGGMLLMAEPVTSAIRSVRKENSKVIYLSPQGALLTAEKSRELAAASHLILLCGHYEGIDERAIESEVDEEISIGDYVLTNGGIAALVLIDAVSRFIPGVLGNQESAERDSLENGLLEGPQYTRPREFEGKEVPEVLLQGDHKAISQWRLEQSERRTYERRPDLYLNYLYKRSIDHKFDEETTTNRDHFKCDKISVVLEVNKLKRAKNFYCKVFGLDAMSCENKFCLPHEGKTIFWLREVQAEKKNIVTLSLSLDCACEEDFCYLLRRWELFGGKLLEKQADEHAVWALAQDLDGHAWIFSWHRMK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_STRGG
Sequence: MPNQSRPKVKKSRALGIALTPKAVKYFEARPYPPGEHGRGRKQNSDYKVRLLEKQRLRAQYDISERQMARAYDRAKKAEGKTGEALVVELERRLDALVLRSGIARTIYQARQMVVHGHIEVNGGKVDKPSFRVRPDDIVQVRERSRSKVPFQVAREGGYDTDGETPRYLQVNLKALAFRLDRDPNRKEIPVICDEQLVVEYYAR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RBS_GLYTO
Sequence: MASSMISSPAVTTVNRAGAGTVAPFTGLKSMAGFPTRKTNNDIASIASNGGRVQCMQVWPTTGKKKFETLSYLPDLDDAQLAKEVEYLLRKGWIPCLEFELEHGFVYRENHRSPGYYDGRYWTMWKLPVFGCTDASQVLKELQEAKTAYPNGFIRIIGFDNVRQVQCISFIAYKPPSF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GATB_PSEAE
Sequence: MQWETVIGLEIHAQLATQSKIFSGSSTAFGAAPNTQASLVDLAMPGTLPVLNEEAVRMACLFGLAIDARIDRQNVFARKNYFYPDLPKGYQTSQMDHPIVGKGHLDITLEDGTTKRIGITRAHLEEDAGKSLHEDFQGMSGIDLNRAGTPLLEIVSEPDIRSAKEAVAYVKAIHALVRYLGICDGNMAEGSLRCDCNVSVRPKGQAEFGTRAEIKNVNSFRFIEKAINHEIQRQIELIEDGGKVVQETRLYDPNKDETRSMRGKEEANDYRYFPCPDLLPVVIEPEYLAKLREQLPELPVQKRERFESQYGLSAYDASVLSASREMADYFEKVQGICGDAKLAANWVMVELGSLLNKDGLEIEQSPVSAEQLGGMILRIKDNTISGKLAKMVFEAMANGEGSADQIIEAKGLKQVTDSGAIEKMLDEVLAANAEQVEQYRAADEAKRGKMFGFFVGQAMKASKGKANPQQVNELLKKKLEA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: MUTH_BUCBP
Sequence: MCVFCEKKLFMHAIGLSGYSIREIVSSLDQPVSNSLVRNKGFVGKILELILGVNVLHGYKCIDFPSLGIELKSIPINSSGYPLEPTFICNIPLKNNSLNITWNNSYFYRKIKKILWIPIIGNRVVSFLDKIVGEAFIWTMSSVQEKILKKDWEEFMDLIIIGKVEYISSKHGQVLQVKKKCKNKHVCIKFINYNGCVKFTNPRAFYFRKSFTWSLLNLSK
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_CORU7
Sequence: MSRASLEKDPREVATMFDAVGKNYDITNTVLSFGQDRLWRKRTRRRLDLAPGDKVLDLAAGTGVSTEELAESGAYCVAADFSLGMLRAGSHRDVPMICADGLNLPFADNTFDAVTISYGLRNLVDFRAGLREMARVTKPGGKLAIAEFSTPVIPGFATVYKEYLMRALPAVAKVVSSNPESYVYLAESIRAWPDQEELAREIRANGWENVGWQNLTGGIVALHSGTKPLD
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: MSS2_YEAST
Sequence: MQRFVSKFVSTPPVPKKFQEIFPKKRTVNKILFQLDTRLTYHEMYPIFLQVSQNTNEENIPWRKKYPYIRSSDIMQMRNVLITLRTQNKFVHKDLLAMEDKLLNIAAELGNNDAISILSFNVIHEYKKENVKSSYEKDIETANEFIKKLYARNHHLTVKLIGDLFFENKTYDKAEKYYQEFLKLENSTKLAGEVHGKLGEIQIKQVNGFLKAEKSWLSCIELLEIERSSRWYFLLARLYMSSEPMKAKALLENCASIGFKECFKTLGFLELNYFNNYERAKEWFKTGMEIMDLECFFGFFDCCVKEENFKGARDCLESVKKLGNDKDKKTMINVFLESRKDSIKLLDKARL
What is the function of this protein?
Required to stabilize mitochondrial cytochrome C oxidase subunit 2 (COX2) and to translocate the C-terminal domain of COX2 through the inner membrane.
What are the official names of this protein?
Protein MSS2, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: RPC8_MOUSE
Sequence: MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVHFRYVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSAEAASSSEELPKKEAPYTLVGSISEPGLGLLSWWTSN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNA.  Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.  Acts as nuclear and cytosolic DNA sensor involved in innate immune response.  Can sense non-self dsDNA that serves as template for transcription into dsRNA.  The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC8, DNA-directed RNA polymerase III subunit H, RNA polymerase III subunit C7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU4M_BOVIN
Sequence: MLKYIIPTIMLMPLTWLSKNNMIWVNSTAHSLLISFTSLLLMNQFGDNSLNFSLLFFSDSLSTPLLILTMWLLPLMLMASQHHLSKENLTRKKLFITMLISLQLFLIMTFTAMELILFYILFEATLVPTLIIITRWGNQTERLNAGLYFLFYTLAGSLPLLVALIYIQNTVGSLNFLMLQYWVQPVHNSWSNVFMWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMLRITLILNPMTDFMAYPFIMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSYMGATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTINLIGELFVVMSTFSWSNITIILMGVNMVITALYSLYMLIMTQRGKYTYHINNISPSFTRENALMSLHILPLLLLTLNPKIILGPLY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TMM81_RAT
Sequence: MKAVATVFICGSLVLITYLPLVVTSPQTLAIPEKLRQAVGRVVVNATACSVTCGLGYKEETSCEVGPDGVRRDCRSQRLECLTNWICGMLHFTIIQRQQFELNCLSSDILTKGQEAFRFTWKLARGIISTNDELFKPFRANSPFLRFKPAYESDSGTYRCDVQQLKNLKLVKRLYFGLRVLPPKLVNLNFQQSLTEDQKLAEEGWEVHLDNQSQPHLPGWRKKVSLALGVGIAAGVVGGVLVNVALCRVLGGTGGNGNLSSL
What are the official names of this protein?
Transmembrane protein 81.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CDT1_ORYSI
Sequence: MYNAPMAQEMSYYEHVQRRHEEKGCLYACIFTALCCFCCYETCECCLDCLCCCCN
What is the function of this protein?
Confers resistance to heavy metal ions (e. g.  cadmium (CdCl(2)) and copper (CuCl(2))) by chelating them at the plasma membrane of root cells, thus stopping their entry and reducing their accumulation (By similarity).  Binds to aluminium (Al) (By similarity).
What are the official names of this protein?
Protein CADMIUM TOLERANCE 1, Cd tolerant 1, OsCDT1.
What is the protein family that this protein belongs to?
Belongs to the CYSTM1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Secreted, cell wall.
Protein: VL1_HPV54
Sequence: MWRPSENKVYLPPTPVSKVVSTDEYVTRTSIYYHASSSRLLAVGHPYFKVQKTNNKQSIPKVSGYQYRVFRVQLPDPNKFGLPDPSLYNPETQRLVWACTGVEVGRGQPLGLGLSGHPLLNKLDDTENAPKYVGAGADNRENVSMDYKQTQLCILGCTPPIGEHWAKGNLCTPNTLAAGDCPPLELVNSYIQDGDMVDIGFGAMDFKTLQTSKSEVPLDVATSICKYPDYLKMAAEAYGDSLFFYLRREQMFVRHMLNRAGTMGEPVPNDLYIKKSSGNLDSSIYAATPSGSMVTSEYQIFNKPYWLQRAQGQNNGICWGNQVFLTVVDTTRSTNLTLCATASTQDSFNNSDFREYIRHVEEYDLQFIFQLCTITLTADVMAYIHGMNPTILEDWNFGITPPATSSLEDTYRFVQSQAIACQKNNAPAKEKEDPYSKFNFWTVDLKERFSSDLDQFPLGRKFLLQAGLRARPRLRPVKRAAPSSSKGTARKRAKTKR
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: JZT24_CHIGU
Sequence: MKAAILLAFAGLALLSVICHASENVEQDSFEEVFSAIFAMEDDLKPKERVCRGYGLPCTPEKNDCCQRLYCSQHRLCSVKAGK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U15-theraphotoxin-Cg1a, U15-TRTX-Cg1a, Jingzhaotoxin-24, JZTX-24, Peptide F5-8.99.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 66 (Jztx-24) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPS_SHIBS
Sequence: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: GSH1_SALDC
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVTEGEAAKEKISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYARIGVEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLADAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCETAQFPLPKVGKDLFRDLKRVAQTLDSIHGGEEYQKVCDELVACFDNPELTFSARILRSMIDEGIGGTGKAFGEAYRNLLREEPLEILQEEEFIAERDASVRRQQEIEAADTEPFAAWLAKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: CYSI_SHEWM
Sequence: MSDGKSVEKEEALSVNEHLKTDSDFLRGTIQEGLDTAVTGSFSEGDQQLIKFHGFYQQDDRDLRNERKEQKLEPLYSFMLRARVAGGVCSPEQWLGVDEISSTLTSSNSIRLTTRQTFQYHGISKRNLRTLIQGLDSKALDSIAACGDVNRNVMCNPNPVESRLHEQAYYWAKQLSDQYLPRTKAYAEIWLGDDKVATSEGDDVEPVYGKTYLPRKFKMAVAVPPDNDVDVYTNDLGFVAVAEEGELVGFNLVAGGGMGSTHGEVQTFPRLADDFGFIKAEDTLKFAEAVLKVQRDWGNRSNRKLSRLKYTIVKYGYEAFKAEVEKRAGVKFEPKRDVVIGDRGDRYGWIKGVDNKWHLTLFIEGGRIKDLPGQPLQTGLREIAKIHKGDFRMTSNQNFIIASVAEEDKAEIEALARSHGLMGKLITETRGRSIACVALPTCALAMAEAERYFPDFLSKVESLQEKHGFLDQGIVIRMTGCPNGCARPFAAEIGLVGKAPGRYNLYLGASFEGTRLNKLYRENIQEAEILSELDSLFARYVAEREEGETFGNFTVRIGAVSAVIDAAKDFHEQHNHA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: SYFA_SHIDS
Sequence: MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAADTIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_LACLM
Sequence: MTEHAIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTMSPEELKTLGSGIILSNTYHLWLRPGDELVAEAGGLHKFMNWDQPILTDSGGFQVYSLVQNKKNITEEGVKFKSHLDGRELFLNPEKAISIQNNLGSDIMMSFDECPPFYQPYDYVKASVERTSRWAERGLNAHRRPNDQGLFGIVQGAGFEDLRRQSASDLTSMDFAGYSIGGLAVGESHKEMNAVLDFTTPMLPEDKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTLMTHFGRVNIRNAKYEYDFTPLDPMCDCYTCTNYTRAYLRHLIKADETFGLRLCSYHNLHFLVNLMKDVRQAIMDDNLLEFREDFCERYGYNQPNAKDF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: KHSE_PROM0
Sequence: MSIPEVGKKIRVTVPSTTANLGPGFDCLGAALDLYNEFIFTRIEGGGDRFDLIMESTDGNHLRGGPENLVFRAAQKVWESANMDPFALEARVKLAVPPARGLGSSATAIVAGLIGANAIMNSPLSKEKLLELAIDIEGHPDNVVPSLLGGLCLTARSSSQRWRIIRCEWHYSIKAVVAIPAIRLSTSEARKVMPRNVPISDAVTNMGALTLLLNGLKTGNEELIKEGMFDKLHEPYRWKLIKGGLEVKDAALNAGALGCAISGAGPSILALCKKENGKNVSQAMVKAWEMSGVASRAPFLNVQTTGSQFSTISGK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.