PharMolix/UniProtQA huggingface dataset:
Protein: RL17_ENT38
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSESKAEATAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GSPD_PSEAE
Sequence: MSQPLLRALFAPSSRSYVPAVLLSLALGIQAAHAENSGGNAFVPAGNQQEAHWTINLKDADIREFIDQISEITGETFVVDPRVKGQVSVVSKAQLSLSEVYQLFLSVMSTHGFTVVAQGDQARIVPNAEAKTEAGGGQSAPDRLETRVIQVQQSPVSELIPLIRPLVPQYGHLAAVPSANALIISDRSANIARIEDVIRQLDQKGSHDYSVINLRYGWVMDAAEVLNNAMSRGQAKGAAGAQVIADARTNRLIILGPPQARAKLVQLAQSLDTPTARSANTRVIRLRHNDAKTLAETLGQISEGMKNNGGQGGEQTGGGRPSNILIRADESTNALVLLADPDTVNALEDIVRQLDVPRAQVLVEAAIVEISGDIQDAVGVQWAINKGGMGGTKTNFANTGLSIGTLLQSLESNKAPESIPDGAIVGIGSSSFGALVTALSANTKSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTNSEGSSNPFTTVERKDIGVSLKVTPHINDGAALRLEIEQEISALLPNAQQRNNTDLITSKRSIKSTILAENGQVIVIGGLIQDDVSQAESKVPLLGDIPLLGRLFRSTKDTHTKRNLMVFLRPTVVRDSAGLAALSGKKYSDIRVIDGTRGPEGRPSILPTNANQLFDGQAVDLRELMTE
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (Probable).  This subunit forms the outer membrane channel (By similarity).  Among its substrates are PrpL, elastase LasB, chitin binding protein D (CbpD), aminopeptidase PaAP, and metalloprotease ImpA (PubMed:29042496, PubMed:29042493).
What are the official names of this protein?
Secretin XcpQ, General secretion pathway protein D, Type II secretion system protein D, T2SS protein D.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. GSP D subfamily.
What are the subcellular locations of this protein?
Cell outer membrane. Note=Most of the protein is in the periplasm which it traverses to contact proteins of the cell inner membrane.
Protein: SYJ2B_HUMAN
Sequence: MNGRVDYLVTEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLQVQNGPIGHRGEGDPSGIPIFMVLVPVFALTMVAAWAFMRYRQQL
What is the function of this protein?
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
What are the official names of this protein?
Synaptojanin-2-binding protein, Mitochondrial outer membrane protein 25.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: RPPH_TOLAT
Sequence: MIDGDGFRPNVGIVICNRNGQVLWARRYGQHSWQFPQGGVDDGETPEQAMFRELYEEIGLKQDDVTILATSRNWLKYRLPKRLIRWESKPVCIGQKQKWFLLRLDAAKEACIQFGCHGQPEFDDWRWVSYWYPVRQVVSFKREVYRRVMKEFAAIAMPYLPPVAKKEPRRKGYR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: SUCC_DEIRA
Sequence: MKLHEYQGKEVLRDFGVNVQDGKVATTPEEVQAIYKEYGQPVVVKAQVHVGGRGKAGGVKYSANEDKALENAKNILGMDIKGLTVNKVLVTKAVDIDAGTEYYVGMIVDRNVQSYTLMASAEGGMEIEEVAATNPEKIIRHRVDPVTGLRPYEAREVAIKAGFRGNLNKIADMMVKMSKAALERDAVLVEINPLFVDADGTPIALDTKFEIDDNAMYRHKDLAHYRELSAEHPLEVEASDYGFAYVKLDDGNVGVLGNGAGIVMTTLDVVNRAGAKPANFLDIGGGAKADVVYNAVKLVSKDPDVKAIFINIFGGITRADEVAKGVIRALDEGILTKPVRMRIAGTAEDEAKALLNEKNSDLIKMYPTMFEAANEAAKEANALGGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: A16L1_CAEEL
Sequence: MADSYRKLIIERLEDVKQRNKQTATLYNNYSKLAEQLEKKHKYGTSSSNSSQLETGELARVKEEMAELYRSKCQNDQRLIDANHRIADFEKKSSAIIAEKIALEATAKSICAKYAKTEVELQRLKVDNDQLNDERIASNTTVTMLTKQIQDIENDRIHFLNKIRELNEQRVDFLNAEVALEEKRRNSRIQDMITSAVQDITDKDTKLEEMLRAMPDTNSNGDLLLGDSVPSRAEFVLECEEGEVNDVHWLDGETFATGGSDRNIKIWKVDGHGGYTRIGTLAGSNAAFTRIDYERDRKHFIASSNDKNVRIWNLDNSRLLSTLSGHSDQVTCVKFYQSHSAVSGSADRVIKIWDIQNQRCSRSLFPASKVLDVATNMGASPSLFASGHFDKKLRFYDGRSTDPVRTVDMGGRITSLDVTMSGCELLVSTRDDTISLIDLRTFQTVHCYSAENYRTSSDLSRVVLSSGNEYVAAGSSNGSIFVWNRNSTKLEKQLCSNSENAIFSLSWNPTGYGLLSSSKQKFVTLWK
What is the function of this protein?
Most likely a component of the atg-5-atg-12-atg-16. 1/atg-16. 2 complex, which is recruited to the preautophagosomal membrane and associates with lgg-2 to promote autophagosome formation (PubMed:24185444, PubMed:26687600).  Although its role in autophagosome formation may be distinct to the role of atg-16. 2, it functions in a partially redundant manner with atg-16. 2 to regulate autophagic processes (PubMed:24185444).
What are the official names of this protein?
Autophagic-related protein 16.1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat tipD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_BACAA
Sequence: MEPFRIHKGTAAVLMNDNIDTDQIIPKQYLKRIERTGFGKFLFDEWRYDNERHENPNFPLNAPDRKGASILITGNNFGCGSSREHAPWALADYGFRVIIAGGFADIFYMNCMKNGMLPIVMDKEMREKLVKTDAREQIEVDLENEVITTSTHRFHFTIEKMWKEKLLNGLDEISITMQYEQEIKEYERRIAAY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: UL91_SHV21
Sequence: MSKPCISEEDFKDCQAFFAKPLPILVAEISKSLANIDFVDTASQQVDQLGIFLDLIGTECFKEVLCPHTSANLTN
What are the official names of this protein?
Uncharacterized gene 30 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL91 family.
Protein: ENGB_STRMK
Sequence: MSLLIERARYHLSAHNVRQLPPDEGAEVAFAGRSNAGKSSALNALTRQNALARVSKTPGRTQQLVFFQVTPEAHLVDLPGYGYAKVPLDLQAHWQAFIDKYFRTREALKGLVVVMDIRHPLKDYDRQMLSYAVQRGLPAHALLTKADKLSRSQQMQSLQKVRKELQSAYGDSVSVQVFSGEDRTGVDEARGVIGGWLGLE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ORF10_SPV1R
Sequence: MQNDWIKLKEFFIYIFLFIDKTNVESITMWNLTQNEYLTLMVGVWIVILFLTWFLLWMVFKIVGYFK
What are the official names of this protein?
Uncharacterized protein ORF10, Gene 10 protein.
What is the protein family that this protein belongs to?
Belongs to the plectrovirus ORF10 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: CH60_BACCN
Sequence: MAKDIKFSEEARRSMLRGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGLRKGIEKAVATAVEELKTISKPIEGKSSIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYASPYMITDSDKMEAVLDNPYILITDKKISNIQEILPVLEQVVQQGKPLLIIAEDVEGEALATLVVNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTDGEVITEELGRDLKSATIESLGRAGKVVVTKENTTIVEGVGSTEQIEARIGQIRAQLEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTSLMNVYAKVASIAAEGDEATGINIVLRALEEPVRQIAINAGLEGSVVVERLKGEKVGVGFNAATGEWVNMLESGIVDPAKVTRSALQNAASVAAMFLTTEAVVADKPEENKPAMPDMGAMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_SHEPA
Sequence: MQLNSTEISDLIKQRIEQFEVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYATLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPIDSDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQIGKTALAIDAIINQKDSGIKCVYVAVGQKASTIANVVRKLEEHGALANTIVVVATASEAAALQYLAPYSGCTMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAEYVEKFTKGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFSQFASDLDDATRAQLEHGERVTELMKQKQYAPMSIADQSVSIFAAEKGYLKSVALNKVGDFEASLLSFMNSEHADLMKTINDTGDYNADIEGELKASLDKFVETQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: QUEA_VIBC3
Sequence: MQVSDFHFELPDELIARYPKAERTASRLLQLDGNSGQLVDGTFKDVLELVEPGDLLVFNNTRVIPARMFGRKASGGKLEVLVERMLDEHTILAHVRSSKPPKPGTELYLGENDEFHAVMQARHDALFEIRFTAETVVLDILNQIGHMPLPPYIDRPDEETDKERYQTVYNQKPGAVAAPTAGLHFDQALLEQIQAKGVELAYVTLHVGAGTFQPVRVENIHDHHMHAEYVEVPQEVVDAIAATKARGGRVVAVGTTSVRSLESAAQDALQKGTELKPFFGDTEIFIFPGYQYQLVDCLITNFHLPESTLIMLVSAFAGYEHTMAAYEHAVKEQYRFFSYGDAMFIRKQTTKA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSCA1_MOUSE
Sequence: MSSLPTSDGFDHPAPSGQSPEVGSPTSLARSVSASVCAIKPGDPNSIESLAMEATKASAEFQTNSKKTDPPPLQVLPDLASSAEQSLAMPFHKSSKEAVVAGNLEKSVEKGTQGLRVYLHTRQDASLTLTTTGMREPQIFAEEKSWHPENQTPSPVNGLQQHRETGSVQREAGQQSVPQDQGCLCDAEDLELHEEVVSLEALRKGELQRHAHLPSAEKGLPASGLCSCPCSEALMEVDTAEQSLVAMCSSTGRQDAVIKSPSVAHLASDNPTMEVETLQSNPSCEPVEHSILTRELQLPEDNVDMSTMDNKDDNSSSLLSGHGQPSVESAEEFCSSVTVALKELHELLVISCKPASEESPEHVTCQSEIGAESQPSVSDLSGRRVQSVHLTPSDQYSQGSCHQATSESGKTEIVGTAPCAAVEDEASTSFEGLGDGLSPDREDVRRSTESARKSCSVAITSAKLSEQLPCTSGVEIAPELAASEGAHSQPSEHVHNPGPDRPETSSVCPGAGLPRSGLDQPPTQSLSTPSVLPPFIFPAADVDRILGAGFTLQEALGALHRVGGNADLALLVLLAKNIVVPT
What is the function of this protein?
Mediates transcriptional and post-transcriptional regulation of SLC5A1.  Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1.  Also involved in transcriptional regulation of SLC22A2.  Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network (By similarity).  Regulates the expression of SLC5A1 in a tissue-specific manner and is specifically involved in its regulation in the small intestine.
What are the official names of this protein?
Regulatory solute carrier protein family 1 member 1, Regulatory subunit of SGLT1, Transporter regulator RS1, mRS1.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Golgi apparatus, trans-Golgi network. Note=Localizes at the inner side of the plasma membrane.
Protein: HSLO_SHEPC
Sequence: MNQDILHRYLFDNADVRGELVQLQESYQQVLDAQAYPPVLQILLGELMAATSLLTATLKFSGDISVQLQGNGPVSLAVINGNNLQQLRGVARWNGELTDNASLADLFGQGYMVITLTPDEGERYQGVVALDKPTLAACVEEYFNQSEQLPTALWLFANGQQAAGMFLQILPSQEDHHQDFEHLSQLTSTIKAEELFTLDAENVLHRLYHQEEVRLFDPIEVSFKCTCSRERSAAAIKTLEQAEVEAILAEEGKIEMGCEYCNANYVFDGIDITTIFANGQNSNIPQ
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_ACIBS
Sequence: MKQQAKSRKPQQPEYIFQVETLSHEGRGIAHYGSHPDHPADKHGKKVFIRYALPGETVKAQITHEAKRLEEAEMVALLAEPSANRVEAVCPHYGICGGCSMQHIHPDEQIRLKQNVLQSHLQHFAGIQPEQWLEPIRSLQSDYRRRARIGVRYLPKQDRLILGFREHHSNRLTSIHTCSVLDKKLSDSLPELRNLLQSLKGKVHIGHVELAKGDHETSLLVRHIEKLNNADVNQLRQFALHKGWQLYLQPKGPESLRRIDEEQGAMRLHYALNAFDVNFAFSPLDFTQVNATVNEQMVQLACELLQLQQGERVLDLFCGLGNFSLPLARCVGAKGVIVGVEASEEMVQRATDNVKRNNLVQASFFSQDLTKDFSHHSWANQGFDALLIDPPRAGAYEIIQYVPNFGAKRIVYVSCNPATLARDAGVLVQHGYQLKKAAVMDMFTHTEHVESIALFEKIQEIND
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: GPMI_NOSP7
Sequence: MTKAPVAPVVLVILDGWGYCEEKRGNAIVAAKTPIVDSLWAAYPHTLIRTSGKAVGLPEGQMGNSEVGHLNIGAGRVVPQELVRISDAVEDGSIALNPALVKICQEVRSRNSKLHLVGLCSEGGVHSHITHLFGLLDLAKNQQIPEVCIHAITDGRDTAPTDGVRAITMLQNYIDRTGIGRIVTLSGRYYAMDRDHRWDRVKRAYDVMTQDGVGDNRTAVEILQASYAEGVKDEFVNPIRIAPGAIEPGDGVIFFNFRPDRSRQLTQALVSPTFNGFERQQITPLSFVTFTQYDSDLPVAVAFEPQNLSNILGEVIANHGLNQFRTAETEKYAHVTYFFNGGLEEPFAGEDRELVSSPMVATYDHAPAMSAVAVTDVAIAAIQKGTYSLVVINYANPDMVGHTGQIDATITAIETVDRCLGRLLESVIKAGGTTIITADHGNAEYMLDDGGNPWTAHTTNPVPFILVEGEKVKIPGYGTNVELRSDGKLSDIAPTILEILQLPQPPEMTGRSLLKTADYELQRTRTPVQVGL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: UVRB_YERPS
Sequence: MSKSFKLHSVFKPAGDQPEAIRKLEEGLENGLAHQTLLGVTGSGKTFTVANVIADLNRPTMILAPNKTLAAQLYGEMKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTRGMIIDQRSILRRLSELQYSRNDQVFQRGTFRVRGEVIDIFPAESDEWALRVELFDEEVERLSIFDPLTGQLQHEVPRFTVYPKTHYVTPRERILQAMEEIKVELAERRQVLLANNKLLEEQRLSQRTQFDLEMMNELGYCSGIENYSRYLSGRGPGEAPPTLFDYLPADGLLIVDESHVTIPQIGGMYKGDRSRKETLVEYGFRLPSALDNRPMRFEEFEALAPQTIYVSATPGKYELEKSGGDIIEQVVRPTGLLDPLIEVRPVATQVDDLLSEIRIRAAINERVLVTTLTKRMAEDLTDYLSEHGAKVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYGDRITASMEKAIGETERRRAKQQAYNEERGIIPQGLNKKIGDILQLGQPSMRGKGKGRGSHKMADTTQYQSLSPKALDQKIRELEAKMYTYAQNLEFEQAAELRDQVHQLRQQFIAIS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOA_PARUW
Sequence: MSTLLLQNLLENGTEFYFFIFVLAIVLLIILSVIGKFISLWFQAFVSGTPIPLFNIIGMSLRKIPPREIVNARINLYKAGLKDIHVGDLETHYLAGGHVPNVVEALIAADKANIPLDWRRATAIDLAGRDIKAAVQTSVNPRVIDCPNHGGYITGVAKDGIQLNCRARVTVRTNIAQLVGGATEETIIARVGEGIVSAIGGSDTHKQVLESPQKISKLVLEKGLDSSTAFLILSIDIVEINLGENIGAKLRTDQAESDIRIAKAEAEKRRTMAVAQEQENLAKVRDMEAKLVEAQAAVPLAMAEAFRSGKLGIMDYQRIQNIQSDTDMRNALAKPDSDKKQN
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: SPNE_DROME
Sequence: MDQEVMDFFDFSKELKRVAAAPQGYISSDPRLMATKFKSSEVPNRELIGTDYVSKIVAKEKCLLNGTLLNEQPQGKRIRTLDDLDTDDEGEETEIRRDDEYYKKFRFNLNRDKNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKSGKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLINNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSRHVKIILMSATIDAKELSDYFTTTNSIPPVITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAIQSRQSYDEALRYGAVLIFLPGIYEIDTMAENLTCMLENDPNIKVSIVRCFSLMTPENQRDVFNPPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRVGRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGSPVEILALALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFNMLEEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQESAIRWAKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMDDREKAIMLKVIIAGAFYPNYFTRSKESCADTDRNIYQTISGHDPCRTVYFTNFKPAYMGELYTRRIKELFQEVRIPPENMDVTFQEGSQKVFVTFKQDDWIEGSSKYVPVSGRVQSEVYKAVMMRQNRVERPIHIMNPSAFMSYVQQRGIGDVIEGRWIPPTKPLNVELLALPSVFDKTISGSITCIVNCGKFFFQPQSFEECIRNMSEIFNAPQQLRNYVTNASAIAKGMMVLAKRDSYFQRATVIRPENQSNRQPMFYVRFIDYGNCTLLPMQLMRLMPRELTEQYGDLPPRVFECRLAMVQPSSVVSGNNRWSTAANDMLKTVAQCGLIDIEVYSLFNNVAAVLIHMRDGIINDKLVELMLCRRSDEDYMSRKDHDFRLRRQESARNLSTAQRQQINEEYLRSCQLPQDHDLPPPPLEKCKTVVMLKGPNSPLECTMRSITRVGLSKRVNIDHLSVNALLLDADPQDHHDHLIVAHEIAESRNGQTLTARGTTLMPNVQGFGALMVMLFSPTMQLKCNKEGTSYVSVLGGLGCDPDTNEPYFAEHDVLINLDVNILEDDVILINQIRYYIDSVFFNFKEENNPAVSVNERVSIYTQLRSLINRLLCKDRRYIERNMSNADFEWETNPELPLPNEPFGKRAIFPMHSLTELQEEDTGRLVQLRENCSMLHKWRNFEGTLPHMTCKLCNQLLESVPQLRLHLLTILHRDREKQIDYCNQ
What is the function of this protein?
Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons.  Involved in the repression of LTR retrotransposon copia.  Also involved in telomere regulation by repressing specialized telomeric retroelements HeT-A, TAHRE, and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements.  Involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin.  Involved in the repression of testis-expressed Stellate genes by the homologous Su(Ste) repeats.  Required for anteroposterior and dorsoventral axis formation during oogenesis.
What are the official names of this protein?
Probable ATP-dependent RNA helicase spindle-E, Homeless.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Protein: UPPP_SHESH
Sequence: MDTFQVIILALIQGLTEFLPISSSAHLILPSQLLGWEDQGLSFDVAVNTGSLLAVVMYFRHELWSMFKAWTDSIITRKQTDESKLSWWIILATIPAVIVGFTAKDFIETYLRNTAVIATTTIVFGLLLWWADRMFRPGFTEFQVGWKKALVIGVAQAMALIPGTSRSGATITAALMLGLSREAAARFSFLMSVPVSLGAAILVTKDLISSGQTIDYQALSLGIIVSFVAAYTCIHLFLKLISRMGMTPFVIYRLALGAILCAFMFA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1947_LISW6
Sequence: MKASISIDEKKDFIRWFLNKHQMKTREAMWVLNYIAGHDQIVKYVHFVDNLEGCARGLSLSAHGVESEPFLFFKGNIMTTDPEKAFHDIRLNWDEELYIELHFEEALSSPEYALVREDNPFTALKLADEEKEMADALIYQSVNQFSRGKLLQQIDDALDARDEAVFHKLVRILHQMDKKEE
What are the official names of this protein?
UPF0302 protein lwe1947.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: PCKA_METS4
Sequence: MSDIGVYNAAFGPDRAGLRNLKRVFWNLEAPSLYEQALQRGEAQLAAGGALVAETGIHTGRSPKDKFVVRDSGTEDQVWWDNNGAITAEQFDRLHADFVAHAEGKDLFAQDLYGGAEPAYRVRARVYTEYAWHSLFIRNLLIRPERDALGAYEPDLTIIDLPSFKADPARHGVRSETVIACDFTRKIVLIGGSSYAGEMKKSVFTYLNYILPKAGVMPMHCSANVGAQGDSALFFGLSGTGKTTLSNDPARVLLGDDEHGWGPKGIFNFEGGCYAKTIRLSREAEPEIYATTERFGTVMENVVIDPVTRLPDFDDASKTENTRCAYPLPFIPNASATGRAGHPKNIVMLTCDAFGVLPPIAKLTGAEAMYHFLSGYTAKVAGTEKGLKGPEATFSTCFGAPFMPRHPSVYGNLLRDLIARHHVDCWLVNTGWTGGGVGTGRRMPIRVTRRLLTAALDGSLAKADYRRDPYFGFAVPTSVPGVEPHILYPVKTWADKAAFAETAKRLVEMFQANFKRFEAHVDADVRAAEPTMSIAA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCA_DICDI
Sequence: MFRNNNNDNNNNDNGFDDENKGIFLDSKIEISDETSLIHKPYHDDYDENGLINNNNNSHNNNNGGNNNNHGPSKVTHRRGKHTFTEADKLKMTKFESLDFPIIDNQIYREYIRRTSKLNHMLKTFGKWIICFMIGVLVGITAYLVKQSVEFVNEFKFDQSGKYLEDERKFIAFLVYYSINILFGVSASLVIIPVGQIASGSGIPEVKGYLNGIRIPQSMNVKTLVGKLVSLILAYSSGLILGPEGPMIHIGSMLGGAIGQVKSKTLKWYPKVLWKYHNDRDRRDFISTGAAAGVAAAFGAPIGGVLFGFEEASSFWSRQLTWRTFFACLIATFTTNIILQGFDMQLHDYGVLKFGLSNKYLYKYSELIPFALIGVAGGLFGALFVNLNAHLSQWRSKFFANKKIYLRVLEVFILITITSTILYCCAAFTPCRSKTQANGSQTNSLDTSSSSILSSSGDNSKNSTKLFKLLNNASGEDKQEDKFIAFFCEQGEYNQMAGLSFNSLDAALRLLFSTSTDIFTIPTLAVFSLISFILTTITSGLMLASGLFIPMMLVGATFGRLVGQVIALFVSVDPCIYALVGASAMMAGFSRMTISLAIIMVELTEGTQYMLPVILSVMIAKWVGDFFNESIYEHLIEQKCYPFLQSQPPKSMIKLGVVDIMKTEVVTLHEVERVSKVIEVLKSEQHFHNGFPVIERPRPLDPNRKDAYGNLEYYEDETTYSGLILRNQLICLLYYRIFCHEQPLPQNPRLLGGNSNRRYNQRRFGRPTEYGYAPADPRMTYELMTQSLARHFPPIDKMNLKKEEIETMYIDLRPYMNLSTIVANETYSYSETYSIFRTIGLRHLPVVNKKNEVVGIVTRKDLL
What is the function of this protein?
Voltage-gated chloride channel.  Chloride channels may have several functions including the regulation of cell volume, membrane potential stabilization and signal transduction (By similarity).
What are the official names of this protein?
Chloride channel protein A.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.