PharMolix/UniProtQA huggingface dataset:
Protein: AROC_PROM1
Sequence: MGSSFGKLFTISTFGESHGGGVGVIIDGCPPRLELDINEIQNDLNRRRPGQSKITTPRNESDEVEILSGLLGNKTLGTPIAMVVRNKDHRPKDYSEIKKTFRPSHADATYQKKYGIQASSGGGRASARETIGRVAAGSVAKQLLTKFAKTEILAWVKRIHDIEAEIHPSEVTFDEIEKNIVRCPNQSAADLMIQRVEAFGKEGDSCGGVIECVVRNPPIGLGMPVFDKLEADLAKALMSLPATKGFEVGSGFGGTYLKGSEHNDPFLPSDSNQLKTATNNSGGIQGGISNGEDIVLRVGFKPTATIRKSQKTIDEDGNAITLKATGRHDPCVLPRAVPMVEAMVALVLADHLLRQRGQCTD
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: UBIG_CERS4
Sequence: MESSSTIDPAEVAKFEAMAAEWWNPHGKFKPLHQMNPCRLDYITQQIAAEFDRDLSAPLPFEGLRLLDIGCGGGLLSEPMARLGAEVIGADAAPRNIPVAKLHAEQSGLTIDYRNTTAEALAAAGERFDVVLNMEVVEHVADPLTYLTACRELLKPGGLMICSTLNRNPKSFAMAIVGAEWVMRWLPKGTHDWSKFITPDELYDLIRKAGLDPVDRKGMVFNPVSWSWSLSARDLSVNYVTASVRRS
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: RNC_RUEPO
Sequence: MKLSAEMKAFEARLGYSFERPELLVRALTHGSISSSTRQDNQRLEFLGDRVLGLVMATALLEADKDATEGQLAPRFNALVRKETCAEVAREADLGAVLKLGRSEMMSGGRRKLALLGDAMEAVIAAVYRDGGFAAAEAVILRLWGARVHQVEADARDAKTALQEWAQARGQTPPRYELVKRSGPDHAPVFTILAELADGRRAEATAGAKRQAEQAAARKLLDSLD
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANT_SALHS
Sequence: MSTSTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQSEFGLTTVQAASLISAAFISRWFGGLLLGAMGDRYGRRLAMVSSIILFSVGTLACGFAPGYTTMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIINILMTFVAAAALWFCFAGNLQNAAIVAGLGLLCAVIFISFMVQSSGKRWPTGVMLMLVVLFAFLYSWPIQALLPTYLKTELAYDPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQILIIPVFAIGGTNVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDDKPFSGAVPLGSGKGAFVKTKS
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_MYCA9
Sequence: MTGPDEIAELVASLTREVADFPEPGVQFKDLTPLFADADGLSRVTDALAQAASGATLIAGIDARGFLLGAAVAIRLGVGVLAVRKAGKLPPPVHAQTYQLEYGTAALEIPADGVELAGRRVAIVDDVLATGGTLAATARLLTTAGADVISAGVVLELSDLGGRAAVAPLPLTALRAI
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_EHRCR
Sequence: MLYKNVDEFIKVIDKTKRIMGLDFGEKKIGIALSDRTNLIAIPYSVYVRRSSRKDLGSLYSIFVENDVGSIVIGWPLELSGVENELCQKVVMFANRIITRYKINICLHDERYSTAMATRLAKLANIKRKESQAIDDKISAVLILQQVLDIIKVYQM
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YM23_MAIZE
Sequence: MTKTYRISSGLLREAVKKITIARDSAFFVDKEILSKSSELKNSLINPCHNVVREFVRESRDCDSDDYKREYRLNDYRLELTQPPSNISRGVIVVKTVRRWELINQKYNADLWIPPAKKGVVITPDIIDKLYLFWDNFLGSYEKEGINRKQNTDPVSKGKVFDLLASRSSNNTNQTPEELREIQTQIEHLTIHFDEGSVHESAGQLKGKFFNKDRQSARDYLLDKLKDDKDKDIVRGMGTYTLECVAIHVLSKLFNVFSLEKTSVLAAALISELDITAKTEYNNALLAKMQREKE
What are the official names of this protein?
Uncharacterized 33.9 kDa protein in mitochondrial linear 2.3 KB plasmid.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: AMY_PECMA
Sequence: MLSLIIAACCVTVALAGTFSNPTCAPGRNTIVHLFEWKWTDIAKECERFLGPNGFCGVQISPPNENRLVNNRPWWERYQPVSYKLQTRSGSEDQLRDMISRCNRVNVRIYSDTVINHMTGVGGSGTGTAGSHWNGDTLSYPGVPFSAWDFNTGNECHSSDMNIHDYNNAEEIRNCRLVSLADLKLSKNYVREEITQYMNHLIDLGVAGFRIDAAKHMWPGDLRAMFGTLHDLNSAVFGSGRKPFIFQEVIDMGGEPISASEYTGIGRVTNFIFGVKLGQVFRNENKASNLHNWGEAWGMPNSNDVVVFIDNHDNQRGHGGGGGPLTHFEPRPYKLATAFMLAHPYGFTRLMSSYNFDRSNTDQGPPHNGDNINDVTINADLTCGNGWTCEHRWREIYNMVAFRNIVMGQNLQHWWDNGNYQIAFGRGNKGFIAMNMDNHNLDQTLQTGLPAGTYCDVISGSYDGSSCSGTEIQVGNDGNAHFSISNSSDDPMIAIHVGAKKGQPKVTT
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: UPP_LARHH
Sequence: MNLTVVNHPLVQHKLGLLREGDISTNKFRTITHELARLLAYEATRDFELEPITIDGWCGKIEVQQIKGKKVTVVPILRAGLGMLDGVLDLVPSAKISVVGLYRNEETLEPVPYFDKFVDSLDERIALIIDPMLATGGSMVATIDLLKRKGCKSIRAIVMVAAPEGIKVVNEAHPDVPVFTASLDSHLNEQGYIIPGLGDAGDKIFGTKHS
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ACOX_PICPA
Sequence: MFKIESIKSQSPQVAIDKERKATKFDINKMFEFLESGKDEAALTKSLMQQIERDTILKTNASYYDLTKDQHRELTAQKIARLASYIEKDAPFFENFQKRLNLIAIVDPQLGTRVGVHLGLFLSAIRGNGTEEQFKYWAFERGAAYLKDVYGCFGMTELAHGSNVAGLETTATFDQKTKEFEINTPHLGATKWWIGGAAHSANHCVVYARLIVSGKDYGVKTFVVPIRDRNHNLHSGVAIGDIGAKMGRDGIDNGWIQLTNVRIPMNYMRSKFTKVTQRQEIVEVPPLEQLAYGALLGGRVTMVTDSFRMAQRFITIALRYSVGRRQFGAKNSSEELKLIDYPLHQRRLLPYLALTYALSISSFDLSQTYDSVLSNLDAAGKSQDFSKLGQAIAGLKNLFCASASLKSTATWYVAQLIDECRQACGGHGYSSYSGFGKAYNDWVVQCTWEGDNNILASNAGRLLCNLLSSCKKKEKKIKGDLSYLNGISNIDKEAICWNKQSMTNLSNSNIDKELFCFNKQVCTVKLINAIQGTIIRLGVRVPNIGSKKSTWDDIAAQRVVLSKLNAVLYMLQHLVLKIKQLGDEEAHKQYLVQIAALFATSQIEMNFASYFLQFKAIDSLEPVADVVSELCLSVRDQVIGLTDSFQFSDYFINSALGSHSGDIYNTYFDTVNNLNNPQVRDGKAAYSEALEAMLRRDPLEVRECFEKSDKVLKKLAPKI
What are the official names of this protein?
Acyl-coenzyme A oxidase, Acyl-CoA oxidase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA oxidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: HIS1_CLOBK
Sequence: MKNVKIALTKGRLEKKAIEIFKTININTRELEDKGRKLIFNCENEEYNIELFLVKAKDVETYVEYGAADIGIVGKDTLMETNKEFYEVLDLNVGKCKFALAALPSFKLDQGYNMKKIATKYPNIAREYFRKKGMDVELIKIEGSVELGPIVGLADAIVDIVETGNTLRENGLVVVEDICEISARMIVNKASMKTKKDEIIKIIENVSEVIRQ
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_HALSA
Sequence: MASVKDRRVESPATDTDLGRGVFEFSDRYSVFDWGEMPDHVPGKGASLCTMGAYTFEQLAAAGVPTHYQGVRTPDGETVRLADAPEAPTQMVIDLTQVPTLPFEDGSYDYDRYHDAGGSNYLVPLEVVFRNAVPVGSSLRTRCAPADVGIDADEWPQGPVELPETIVEFSTKYEEQDRYLSRSMADEIAGDADIAELDALARRVNETITDCAADAGFVHDDGKLECVYVDGEVRVADVAGTFDENRFRFDGREVSKEAVRQFYKRSDPEWVGAVKDAKRAADERGVADWKSLCEPSPDPLPPEILQAAADLYAAGANRYTAREWFDAPPLGDALDAFE
What are the official names of this protein?
Putative phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family. Highly divergent.
Protein: PTH_NEIMB
Sequence: MSNTIKMVVGLGNPGKEYEQTRHNAGFWFLDELAWKWKASFKEEKKFFGEVARAALPDGDVWLLKPATFMNRSGQAVAALAQFYKIKPEEILVVHDELDIPCGRIKFKLGGGNGGHNGLKDIQAKLGTADYYRLRLGIGHPGDRNLVVGYVLNKPSTEHRRQIDDAVAKSLQAIPDILAGKWEEATRFLHSK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_ECOLI
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTLLASGN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: LSG11_ARATH
Sequence: MGKNEKTSLGRALVKHHNHMIQETKEKGKSYKDQHKKVLESVTEVSDIDAIIEQAEEAERLFAIHHDSATPVPINMDTGSSSSGITAKEWKEQRMREEALHASSLQVPRRPHWTPKMNVEKLDANEKQAFLTWRRKLASLEENEKLVLTPFEKNLDIWRQLWRVLERSDLIVMVVDARDPLFYRCPDLEAYAQEIDEHKKTMLLVNKADLLPSYVREKWAEYFSRNNILFVFWSAKAATATLEGKPLKEQWRAPDTTQKTDNPAVKVYGRDDLLDRLKLEALEIVKMRKSRGVSATSTESHCEQVVVGFVGYPNVGKSSTINALVGQKRTGVTSTPGKTKHFQTLIISEDLMLCDCPGLVFPSFSSSRYEMVASGVLPIDRMTEHLEAIKVVAELVPRHAIEDVYNISLPKPKSYEPQSRPPLASELLRTYCLSRGYVASSGLPDETRAARQILKDYIEGKLPHFAMPPEITRDDENETADDTLGAETREGSQTEKKGEEAPSLGLDQVLDDLSSFDLANGLVSSKTKQHKKSHRKQ
What is the function of this protein?
GTPase that might be redundant with LSG1-2 for ribosome biogenesis (Probable).  Binds to 23S rRNA (PubMed:25319368).
What are the official names of this protein?
GTPase LSG1-1, AtLSG1-1, DAR GTPase 6, Protein YEAST LSG1 ORTHOLOG 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLS8_ARATH
Sequence: MSYLLPHLHSGWAVDQSILAEEERLVVIRFGHDWDETCMQMDEVLASVAETIKNFAVIYLVDITEVPDFNTMYELYDPSTVMFFFRNKHIMIDLGTGNNNKINWALKDKQEFIDIIETVYRGARKGRGLVIAPKDYSTKYRY
What are the official names of this protein?
Thioredoxin-like protein YLS8, Protein YELLOW-LEAF-SPECIFIC GENE 8.
What is the protein family that this protein belongs to?
Belongs to the DIM1 family.
Protein: CHD1L_BOVIN
Sequence: MERVGAATPEGDMPGFLLALQSKSRAEAPRARVQEQDLRQWGLTGIHLRPYQLQGVNWLAQCFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFLILCPLSVLSNWKEEMERFAPGLSCVTYAGDKDKRACLQQDLKQESRFHVLLTTYEICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELYSLLSFVEPDLFSKEQVEDFVQRYQDIEKESESASELYKLLQPFLLRRVKAEVATELPRKTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVKLQNVLSQLRKCVDHPYLFDGVEPEPFEIGDHLIEASGKLHLLDKLLAFLYSKGHRVLLFSQMTQMLDILQDYLDYRGYSYERVDGSVRGEERHLAIKNFGQQPIFTFLLSTRAGGVGMNLTAADTVIFFDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNTIIEGGHFTLGAQKPAADADLQLSEILKFGLDKLLSSEGSTMHEIDLKSILGETEDGHWVSDALPTAEEGSREPEEGKNHMYLFEGKDYSKEPSKEDRESFEQLVNLQKTLLEKTSQEGRLLRNKGSVPIPGLVEGSTKRKRILSPEELEDRRKRRQEAAAKRKRLLEEKRKKKEEAEHKKKMAWWESNNYQSFCLPSEESEPEDGEDESSAQLEYEDPDSTSIRYVSGDVTHPQAGAEDAVIVHCVDDSGRWGRGGLFTALETRSAEPRKRYELAGKMKDLSLGGVLLFPIDDKESRNEGQDLLALIVAQHRDRANVLSGIKMAALEEALKKIFLAAKKRKASVHLPRIGHATKGFNWYGTERLIRKHLASRGIPTYIYYFPRSKAAILHLQASSSSSGQLVS
What is the function of this protein?
ATP-dependent chromatin remodeler that mediates chromatin-remodeling following DNA damage.  Recruited to DNA damage sites through interaction with poly-ADP-ribose: specifically recognizes and binds histones that are poly-ADP-ribosylated on serine residues in response to DNA damage.  Poly-ADP-ribose-binding activates the ATP-dependent chromatin remodeler activity, thereby regulating chromatin during DNA repair.  Catalyzes nucleosome sliding away from DNA breaks in an ATP-dependent manner.  Chromatin remodeling activity promotes PARP2 removal from chromatin.
What are the official names of this protein?
Chromodomain-helicase-DNA-binding protein 1-like.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage. Probably recruited to DNA damage sites by PARylated PARP1.
Protein: PCY1A_CRIGR
Sequence: MDAQSSAKVNSRKRRKEASSPNGATEEDGIPSKVQHCSVGLRQPAPFSDEIEVDFSKPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYPIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEERSIDLIQTWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRMLQAISPRQSPSSSPTHERSPSPSFRWPFSGKTSPSSSPASLSRHKAVTCDISEDEED
What is the function of this protein?
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
What are the official names of this protein?
Choline-phosphate cytidylyltransferase A, CCT-alpha, CTP:phosphocholine cytidylyltransferase A, CCT A, CT A, Phosphorylcholine transferase A.
What is the protein family that this protein belongs to?
Belongs to the cytidylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Endoplasmic reticulum. Nucleus. Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form.
Protein: KUP_ENT38
Sequence: MSTDNKQSLRAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLILVVSLKYLSFVMRADNAGEGGILTLMSLAGRNTSARMTSFLVIIGLIGGSFFYGEVVITPAISVLSAIEGLEIIAPQLDTWVVPLAIIVLTLLFAIQKHGTGLVGKLFAPIMLAWFLILAALGLRGIMGNPEVLQALNPIWAVHFFLEYKTVSFVALGAVVLSITGVEALYADMGHFGKLPIRLAWFTVVLPSLVLNYFGQGALLLKNPEAIKNPFFLLAPDWALVPMLIIATLATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFINWLLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVAYRNWHWNKFLVALILVGLLCIDLPLFSANLDKIVSGGWLPLTLGLVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAQKVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLIVGKRPWYLRLRGKLYLILQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFM_DROME
Sequence: MLLTLRVQGARHWLKSTRCLASSAAPAKSPSSPPQLEVSGSTYATDGWTNVTPKILSYVGANKHLQTDHPLSIIRQRIVNYFYGAYRNQRGNPLFSVYDQMNPVVTVQQNFDNLLIPADHVSRQKSDCYYINQQHLLRAHTTAHQVELISGGLDNFLVVGEVYRRDEIDSTHYPVFHQADAVRLVTKDKLFERNPGLELFEETWSGTLADPKLILPSSKFMDQTKQPCHTLEAVKLMEHEMKHVLVGLTKDLFGPRIKYRWVDTYFPFTQPSWELEIYFKDNWLEVLGCGIMRHEILQRSGVHQSIGYAFGVGLERLAMVLFDIPDIRLFWSNDSGFLSQFSEKDLHNLPKYKPISHYPQCTNDLSFWLPQDIEVDAGFSPNDFYDLVRSVAGDMVEQISLVDKFKHPKTGKSSVCFRIVYRHMERTLTQAEVNEIHKQIASASVDSFNVQIR
What is the function of this protein?
Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.
What are the official names of this protein?
Probable phenylalanine--tRNA ligase, mitochondrial, Phenylalanyl-tRNA synthetase, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MIDN_DROME
Sequence: MDKSAATNSATADGQNEAAAAAAAAATAAGCGSNNSSSTSSSNNTANSNNALQRLATTTSAVVASPMTINLNISTTTGGNFGVSVEPHISVESLKKIIAKKLKVAKDRICLLHREKELQDGTLRDHNLMDGSKIILIPNVETGLLAQRPENTVMQALESLNDAQVNDFLSGKTPLNLSMRLGDHMMLIQLQLSTVNPAGGGAATVAPVAGGASGSSINAAASTTSTVPVMPAGTGCSGANSTSLSSSAVLAAAAAGVGGSTGTSGSGTSSSSSSTSSSSSSSSSSSRTRSSGQRSSGRIGHGHVHSHQHPSLHAANWHGFSHGHGHGHSHGNGHGHHHHHHHHHHHHHHHHNASAVAAGSGGGMSSLRKMYGDLPSSSGASGSAPATGTGQSQSSSTLNGPDLTKLLIKGGIQNIVNSFALKDAGANARPVANGGSGSSPGKPVLEQSPIKSLSNLVSSPIKMTTIKNIPLPTTAATSSSSSCNCSSAAPSSSSSTSSGACATGGCQQDPIAAKLTSCLCTRLPTPSVAPPVATLVAPAPVARSGSTSSPSKCPESSCSGANAGFAARSTLAGTRVTFSGNSMLHKTGNNRITRTKHRHYHGQGHGHGHGNGHSSSSSSSSSSSSSHFFNHACAGNQPSVNAAAFATSSSSSSSSPSSSSSSPSKRRKLEQGMGAGAVGATAATATAAATVALPASTSATTAEPDDSLLGVSDTRTLAEASRNLTQTLRKLSKEVFTNKIDLSGAGVVSSGRSSSSGATSSGAASGEEAPRKSGSGAVIESMKNHGKGIYSGTFSGTLNPALQDRFGRPKRDISTVIHILNDLLSATPQYGRGARISFEAPTTGSVSGSGSGSGSSGSSSTTSSGSGLHHGSRSKMYSSKHHNCAKCNSRAQQQQQQSATLASGSGGSCSFRDCPSYHSSSAATKASTSSKSSSHSCCQTAEAPSSMTSQSNGCTCRYRRDDGQGEREREHTCQKCTVELANMKTRSKMDQLRLVMQQHKQKREARKLKSGPYATAASASAADSLSSIAAGGTAAVPMGAAAQYSAVSALVATPLQPAAVPVQTGKAAPANSITGNSSNANVNGNTSTAPATAATSAAAAPTAAPPSEVSPNHIVEEVDTAA
What is the function of this protein?
Facilitates ubiquitin-independent proteasomal degradation of polycomb protein Pc by interacting directly with the proteasome and recruiting Pc to it.
What are the official names of this protein?
Midnolin homolog, Protein stuxnet.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPA_CLOBH
Sequence: MKENKIRKNKEFRHVYRRGKSYSNRLLVLYICKNRCNINRLGVSVSKKVGKSVIRNRVKRLIKESYRLNLDENMKKGYDLVFIARNSSNDRDYKDIESALINLLKKAGIYN
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ISCS_HISS2
Sequence: MKLPIYLDYAATCPVDERVVKKMMEFLSIDGNFGNPASRSHKFGWQAEEAVDVARNHIADLIGADSREIVFTSGATEADNLALKGVMRFYQTKGKHLITCKTEHKAILDTCRQLEREGFEVTYLDPKSDGLIDLEELKSVIRDDTVLVSIMHANNEIGVVQDIAKIGEICRERKVLFHTDATQSVGKLPINLSELKVDLLSMSSHKLYGPKGIGALYVCRKPRVRLEAIIHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMPRLTALRDRLYNGLKDIEETYVNGSMEQRLGNNLNISFNYVEGESLMMALRDIAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFTVGRYTTEEEIDYSIGLVKSAVKKLRDLSPLWDMFKEGIDLNSIEWTHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_VARPS
Sequence: MSTTEVVRDAQSAENYNPLAKQKAAAKLSRIPVKVVQQGEVLKKPEWIRVKAGSPTTRFYEIKQILRESNLHTVCEEASCPNIGECFGNGTATFMIMGDKCTRRCPFCDVGHGRPDPLDKDEPLNLAKTIAKLRLKYVVITSVDRDDLRDGGSQHFVDCITNIRELSPMTQIEILVPDFRGRDDRALEILKAAPPDVMNHNLETAPRLYKEARPGSDYQFSLNLLKKFKALHPQVPTKSGIMVGLGETDEEILQVMRDMRAHDIDMLTIGQYLSPSGSHLPVRRYVHPDTFKMFEEEAYKMGFSHAAVGAMVRSSYHADQQAHAAGV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIZ_SALHS
Sequence: MSDIEAQRIAARIDTVLDILVAGDYHSAINNLEILRAELLDQVKDGISPSQAPGSPWEI
What are the official names of this protein?
UPF0509 protein YciZ.
What is the protein family that this protein belongs to?
Belongs to the UPF0509 family.
Protein: HTRA4_HUMAN
Sequence: MIRPQLRTAGLGRCLLPGLLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTTPVFDLCRCCRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCGCPTLGGAVCGSDRRTYPSMCALRAENRAARRLGKVPAVPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEKVAPSVVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPDVSSGVYVCKVVEGTAAQSSGLRDHDVIVNINGKPITTTTDVVKALDSDSLSMAVLRGKDNLLLTVIPETIN
What is the function of this protein?
Serine protease.
What are the official names of this protein?
Serine protease HTRA4, High-temperature requirement factor A4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Secreted.