PharMolix/UniProtQA huggingface dataset:
Protein: IL12A_BUBCA
Sequence: MCPLRSLLLISTLVLLHHLPHLSLGRSLPTTTASPGRSCLDYSQNLLRAVSNTLQKARQTLEFYSCTSEEIDHEDITKDKTSTVEACLPLELATNESCLASRETSFITNGRCLASGKTSFMTTLCLRSIYEDLKMYHVEFQAMNAKLLMDPKRQVFLDQNMLAAIAELMQALNFDSETVPQKPSLEELDFYKTKVKLCILLHAFRIRAVTIDRMMSYLSSS
What is the function of this protein?
Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine.  IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity.  Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits.  Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2.  In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity).  As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity).  Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers.  Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
What are the official names of this protein?
Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPP_ECO5E
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIC_ACIBC
Sequence: MNQLTNLSSAEISAQHEQDAKDLTRILPASKKVYIEGSRPDIQVPMREISLTDTPTGLGGEHNPPIMVYDTSGVYTDPNVQIDLNKGLPSVRQKWIEERNDTDVLSGLTSKFGQERLKDIRTADIRFAHIQNPRRAKAGKNVTQMHYAKQGIITPEMEYIAIRENQRQREAVDMRQHPGQNFGAKNLKEITPEFVRQEVAEGRAIIPANINHPELEPMIIGRNFLVKINANIGNSALGSSIDEEVAKMTWATRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGVAENLTWEIFKDTLIEQAEQGVDYFTIHAGVLLRYVPLTANRLTGIVSRGGSIMAQWCLAHHEENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIQDANDEAQFSELKTLGELTHRAWEHDVQVMIEGPGHVPMHMIKENMDLQLEVCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFNLSLDPDTARSMHDETLPKEAHKSAHFCSMCGPKFCSMKITQNVRDYANNLTNSDSEVEEGLKAMKEVYQEQGQKLYHKV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: T2R42_PANPA
Sequence: MATELDKIFLILEIAEFIIGMLGNVFIGLVNCSEGIKNQKVFSADFILTCLAISTIGQLFVILFDSFLVGLASHLYTTYRLGKPVIMLWHMTNHLTTWLATCLSIFYFFKIAHFPHSLFLWLRWRMNGMIVMLLILSLFLLIFDSLVLEIFIDISLNIIDKSNLTLYLDESKTLYDKLSILKTLLSLTSFIPFSLSLTSLLFFFLSLVRHTRNLKLSSLGSRDSSTEAHRRAMKMVMSFLFLFIVHFFSLQVANWIFFMLWNNKYIKFAMLALNAFPSCHSFILILGNSKLRQTAVRLLWHLRNYTKTPNALPL
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 42, T2R42, T2R55.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EFG_LEPIN
Sequence: MSTAVAEFKPSEKLLKTRNIGISAHIDSGKTTLTERILFYTNRIHAIHEVRGKDGVGAKMDSMDLERERGITIQSAATYCQWKNHTINIIDTPGHVDFTVEVERSLRVLDSAILVLCGVAGVQSQSITVDRQMRRYNVPRVAFINKLDRTGANPFRVIEQLKEKLKHNAVPVQIPIGLENDLKGIVDLVTMKAYYFEGKDGMDIQEKEIPDDLKELAQKKHEELLDAASMFSDELTEALLEGTPTEEMIKKAIRTGTIELKMTPVFMGSAFKNKGVQKLLDGVLDYLASPVDVKNKALDQNNNEEMIVLESNFEKPLVCLAFKLEDGRYGQLTYVRVYQGKLAKGMTIYNMSNNKKHNVGRLCRMHSDEMEDIDSAEAGDIIALFGIDCASGDTFTDGKLKVSMESMFVPAPVISLTIEAKESKHLNNLAKALNRFTKEDPTFQTHVDQESGQTIIKGMGELHLEVYIERMKREYGVELITGAPQVAYRETITSKADFDYTHKKQTGGQGQFGRVAGYMEPIPLEETLDYDFVNKVVGGAIPREYIQSVDKGFKSCLERGSLIGFPIIGVRCVINDGAYHDVDSSDMAFQIAGRYAFRQGFNKANPQILEPIMKVEVDGPSEFQGAILGSLNQRRGMILNTTEEDAYCKTEAEVPLADMFGYSTVLRSSTQGKAEFSMEFSRYAPVPRNVAEELMKKYKVNNKDED
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR2_DEIRA
Sequence: MKVLVIGSGGREHAIVDACARAGHEVLCTPGNPGIAAQARLLASPQDAPTLADLAVREGADVVIVGPEAYLAAGVVDECERRGVPAFGPSQAASRLEGDKAWSKAFMVRHGIPTAQHRSFDTLDAALSHAATQTPPIVVKDAGLKAGKGVTIAHSVAEAEAALREIFTQTGAQAVIEDFMTGQEVSILALTDGKRYALTPPSQDHKTIYEGDTGPMTGGMGVICPFPVGEEQLNIIRRDIVEKTLAGMRAEGIPFRGVLYAGLMLTPQGPKVVEFNARFGDPEAEAVLPLLESDLAQHALDAARGQLDPAQVRFRDGASAVVILAAPGYPAEPRKGIVLDIPADSPEAKVFHAGTTERDGQLVSSGGRVLAVTGLGESREDALSRAYALADCIGFVGAQLRRDIGFRIGLGGKPN
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: VNPA_TROCA
Sequence: SGSETAKIGDGCFGLPIDRIGSASGMGCGSVPKPTPGGS
What is the function of this protein?
Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity.  Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3) (By similarity).
What are the official names of this protein?
Natriuretic peptide TcNP-a.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF1_WOLSU
Sequence: MLISKLTPFIERFEEITRLLGTMEVISDIKRMTELSKEQSALEALVLKAKEYLQTHRSIQENRALFEDKELGDLAKEENKLLEESLESLESEIKLLLIPKDPNDDKNIYLEIRAGTGGDEAGIFVGDLFKSYCRYADLKGWKVEIISSSENSVGGYKEVIALIKGNGVYSRLKYEGGTHRVQRVPETESQGRIHTSAITVAIMPEVDDVEVNINPNDLKIDVFRSGGHGGQSVNTTDSAVRITHLPTGISVSMQDEKSQHKNKDKALKILKARLYEAELEAKLSENSAARKLQVGSGDRSERIRTYNYPQNRLTDHRIGLTLYSLEEIMLSGNFDQVVDPIVAHYQAEMMKESED
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VELB_COCH5
Sequence: MAASMAHYQGHLSNRITTGRAETVGQAQYPPRRAERKYKLEVEQQPIRARMCGFGDKDRRPITPPPCIRLVVLDEMDRELDFNEIDSTYFVLMVDLWNESGQSAVNLVRHSSAAPTVSISSSTTTSYPPPPERSHYVATTIPGYDAHSQAYRHQQHQHQHQHQHMQPQPMAAAGYGPGAHTGVAVPPYYPPTPQPPTPTYQQYPAPAPAAPYGQAPAPSAMIPATPMSSNHTRNLIGMNAVNACRLNDTKNKPGFWFVLQDLSVRTEGTFRLKLFLFDIGAGDGTNATVAADGPTRGKGKCLAVNFSDPFTVYSAKKFPGVIESTPLSKCFAQQGIKIPIRKDGPKLPNQAEYDADD
What is the function of this protein?
Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (PubMed:25080135).  The velvet complex acts as a global regulator for secondary metabolite gene expression (By similarity).  Component of the VEL2-VOS1 heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity).  The complex binds DNA through the DNA-binding domain of VOS1 that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity).  The VEL2-VOS1 complex is required for normal pseudothecium development and regulates asexual spore compartmentalization, pigmentation and germination (PubMed:25080135).
What are the official names of this protein?
Velvet complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VelB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear localization is mediated by VEL1 (By similarity).
Protein: DXR_CAMFF
Sequence: MILLGSSGSIGKNVAFLAMKYGIKLDALACKTDYKELNSQISKFNPKFVYIEDNKLKNLVEHSRVFTSKDGIDKFLEACYDEFGSTVVINSLVGFSGLRPSLVSQKLGFKLALANKESLVAGGKFLDTKSINPIDSEHFGLKFLLKNRPAVKKMIITASGGAFYDMHINELEFVTAKSALKHPNWSMGAKITIDSATMANKLFEVLEAYHLYGIKDIDAFIERTSCIHALISFMDGSTTAHISRTDMKLAIAHAIGLEEKEILEPIDILSLKNISFNTINLKKYPIFTLKKDVLNNPDLGVIINAANEEMVYKFLNNEISFLDINRAVFKSLDKFGSVKIDDEDTVFEIDKKVREFCKGF
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: TRAF_AGRFC
Sequence: MSKRAVIRFLGVAGLVLSGATVMGLIGGYRVNVTPSEPLGLWRVEKLRRPVQSGDLVFVCPPHNAFFEEAWLRGYLRSGLCPGWFAPLIKSVLALPGQRVEIADRIVIDGHPVSASTVSATDSEGRAIAPFAGGVVPPGFLFLHSSFASSYDSRYFGPIPDSGLLGLARPVFTFDP
What is the function of this protein?
Involved in conjugal transfer of the plasmid.
What are the official names of this protein?
Conjugal transfer protein TraF.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26C family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL29_ACIB3
Sequence: MKTKDLREKSVEELKALLDEQQLNQFRLRMAKATGQLGKSHEVQVARKTIARIKTLLTEKQGNGQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL9_RUEST
Sequence: MQVILLERVAKLGQMGDVVDVKPGFARNYLLPQGKAQTASDANIAAFEAQKAQLEARNLETKKEAEALGEKLGGQQFVVIRSASDGGNLYGSVTTRDAADVATEEGFSVDRKQVIIREPIKTLGLHIAEVHLHPEVMVTIELNVARSPEEAELQASGKSIQELAAEEEAAAEFEISELFDDIGGAASDDEGDAPAAAADEEESK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: KTHY_CAMC1
Sequence: MYVLFEGIDGVGKSTQIEILASKFSDAIVTKEPGGTQLGVNLREILLRSSIKIGKRAEILLFLADRAEHFEKLVAPNLGKLILSDRGFISGIAYALANDENLDENVLLELNKFALNDKFADKIIFFEASRELISSRLKARGTSDKIEARGLEYLLKVQSLMKQILIKNGFETLFIDASKSIELISKEIENFINFK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: GLGB_NOCFA
Sequence: MSGPEDPADRRHGEVPAPRRDIPRPLVERRDLMLLAAGTHRDPHTVLGAHPHPDGTVVRVLRPHAAKVSVRVGGVDHPLDSVGYGVFAAVLPHPELMDYRIVTEYPGGPTVIAADGFRFLPTLGELDLHLIGEGRHEHLWHVLGAHPRRYTTLDGPVSGTSFAVWAPNARGVTVIGDFDGWSGNTAPMRALGTSGVWEVFVPDVGSGTKYKYRVHGADGRVVDHADPLAFATELPPATASVVTGSDYTWQDAQWLERRRSTDPTRSPMSVYEVHLGSWRPGLGYRELAEQLADYVRAAGYTHVELLPVAEHPFGGSWGYQVTSYYAPTARFGSPDDFRAFVDHLHGAGIGVLLDWVPAHFPRDEWALARFDGTPLYEHPDPRRGEQLDWGTYVFDFGRNEVRNFLVANARFWIEEFHIDGLRVDAVASMLYLDYSRGENWEPNIHGGRENLEAVAFLRELNDVVHRAHPGVVTIAEESTTWPGVTRGTEVGGLGFTMKWNMGWMHDTLGFLARDPIHRSWHHNEITFSLVYAWSENYVLPISHDEVVHGKGTLWTRMPGDDFAKAAGVRALLAYMWAHPGKQLLFMGQDFGQFREWSHDRGLDWGELDNPLHRGIATAVRDLNRVYRATPALWSQDTTPGGYAWIEADDRDRNVLAFLRYGSDGSTVACVFNFSGALHGEYRVGLPIAGEWTEILNTDAADYGGSGVGNYGVVRTEEIPWHGRPVSATVALAPNSAVWLAAPRA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: LFTR_SHEPA
Sequence: MNSLSYLNHAQQAFPPPEQALIEPNGLLAVGGDLHPERLLNAYYNGIFPWFNLDDPILWWSPDPRAVFVPGNMKISRSLVKYLKKQNWTYTINHAFEAVTAGCAEPRAGQDGTWISSEIQQAYLSLHHQGHAHSLEVWQNNELIGGLYGLAIGQVFCGESMFHRTTNASKAAMIVLQQHLQRCGFKLIDAQVVNPHLDSLGAKSIKRDDFLRLLAHLRDGTVSLDSWRKSEVTIEL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_HELPJ
Sequence: MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKIRSLFLQAKAAFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGNHVLTSYPVQNAFFDHARTRTEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGPNSYEQVRFFYQELGLLDKIELFAFHNNITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVVPQNELLPKKLFEVIRKLNQKDDQGNKNLTTISAKLQQKIAKDGAKTIIETILSA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FBPAP_IGNH4
Sequence: MAQKTTISVIKADIGSLAGHHTVHPDCMAAASRVLAEAKKNGVINDFYVTHVGDDLILIMTHTKGVDHPDVHGLAWEAFKKAAEVAKELGLYAAGQDLLSDAFSGNVRGLGPAAAEMEIEERPSEPIVIFAADKTEPGAFNLPLYKIFADPFNTAGLVIDPRLHDGFVFEVVDVFEDKGVHLNTPEELYDLLALIGTPSRYVIRRVFRKDGKIAAVVSVERLNLIAGKYVGKDDPVMIVRAQSGFPAVGEVLEPFTFPHLVAGWMRGSHNGPLMPVPVRDARPTRFDGPPRVIALGFQVKNAKLVGPSDLFDDPAFDEARRTANKVADYIRRHGPFMPHRLDPSEMEYTTLPQVLERLKDRFKPVKDLPVPKVKHSEMLSGAEEAHD
What is the function of this protein?
Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
What are the official names of this protein?
Fructose-1,6-bisphosphate aldolase/phosphatase, FBP A/P, FBP aldolase/phosphatase.
What is the protein family that this protein belongs to?
Belongs to the FBP aldolase/phosphatase family.
Protein: TRPR_ACTSZ
Sequence: MYISRNMDHWNTFIETLRTAFKEGKEQEFLTLLLTPDERDAVGLRLQIVAQLLDKNVPQREIQQNLSTSAATITRGSNMLKMMDPDFLAWVKEQVDAETQS
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
What are the official names of this protein?
Trp operon repressor homolog.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_SULTO
Sequence: MIIVISGPPGSGKSTVAKILSKNLSLKYISAGHIFRELAEKEGLSLLELNKKAEENFEIDKKIDREIFRIASTEKNIIIESHIGGWLLKDIADITVYLNASIEIRAMRIAKRDNIPFTKAIEQIIEREESHSRRFLAYYGIDLSDLSVFDLVINTDNLQPDEISKIIEAYLNFMLAKNIH
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_METI4
Sequence: MISYSVKQLASLVGGIVEGEPEIEITGISDILDAKKGQITFLSNPRYEAAVEKTQASAIVVSKSYKSSSPITLIRVDSPSLAFSQIISLFSPQPFSYEPGIHPTALIGREVEIGKEVSIQPYAVIEDKVKIGDGCVIGAYVFIGRESIIGEKSFFYPHVTIRERSRIGKRVILHPGAVIGSDGFGYEQTNGRHEKIPQVGIVQIDDDVEIGANTTVDRGRFGKTWIQEGCKIDNLVQIAHNVIIGKNSIIAAQTGISGSTSLGEHVTLAGQVGIAGHIHIGDGATITAQSGVTKDVPPRAVLSGRHARPINLTHKLEVLYNKLPELWERLKKLEKKYDGDSPRPEADPYNS
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: VWF_BOVIN
Sequence: MFPTRLARLLLAVALTLPGALCGEGALGKSSMARCSLFGADFINTFDESMYSFSGDCSYLLAGDCKTHSFSIVGDFQGGRRMGLSVYLGEFFDIHVFVNGTVLQGGQHVSMPYATRGLYLETEVGHHKLSSESYGFVARIDGSGNFQILLSDRHFNKTCGLCGDFNIFAEDDFRTQEGTLTSDPYDFANSWALSSEEQRCPRVSPPSSSCNVSSELQKGLWEKCQLLKTASVFARCHALVDPEPFVALCERMLCACAQGLRCPCPVLLEYARACAKQGMLLYGWADHSSCRPDCPTGMEYKECVSPCHRTCRSLSITEVCREQCVDGCSCPEGQLLDEGRCVESTECPCVHAGKPYPPGASLSRDCNTCICRNSQWVCSNEDCPGECLITGQSHFKSFDDRHFTFSGVCQYLLAQDCQDHSFSVVIETVQCADDPDAVCTRSVTVRLPSPHHGLLKLKHGGGVALDGQDVQIPLLQGDLRIQHTVTASLQLNFGEDLQIDWDGRGRLLLKLSPVYAGRTCGLCGNYNGNQRDDFLTPAGLVEPLVEHFGNSWKLRADCEDLQEQPSDPCSLNPRLTKFADQACAILTSPKFEACHSAVSPLPYLRNCRYDVCACSDGRDCLCDAVANYAAACARRGVHVGWREPSFCALSCPHGQVYQQCGTPCNLTCRSLSHPDEECTEVCLEGCFCPPGLFLDETGSCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHSATSGAPGSLLPEAVLSSPLSHRSKRSLSCRPPMVKVVCPADNPRAEGLECTKTCQNYDLECMSTGCVSGCLPAPGMVRHENRCVALERCPCFHQGREYAPGDRVKVDCNSCVCQDRKWNCTDHVCDASCSALGLAHYFTFDGLKYLFPGECQYVLVQDHCGSNPGTFRVLVGNEGCSVPSLKCRKRITILVEGGEIELFD
What is the function of this protein?
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V.  Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
What are the official names of this protein?
von Willebrand factor, vWF.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules.
Protein: ACPX_STRVG
Sequence: MSDRPFTLADLQRILVEAAGADESAGPDDILDTTFALLGYESLALLETGGCIEREIGISLDDDTLTDALTPRELIDHVNERLAAARVA
What is the function of this protein?
Acyl carrier protein.
What are the official names of this protein?
Monensin polyketide synthase acyl carrier protein, ACP.
Protein: IMP10_NAUMA
Sequence: NSTMNSLLQLGR
What are the official names of this protein?
Uncharacterized protein IMPP10.
Protein: MATP_CITRI
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYVEASAAQEAVEMLLTLENEPVRVNVWIEEHLNPALFNRLKQTIRARRKRHFNAEHQHTRKKSIDLEFLVWQRLAGLAQRRGKTLSETIVQLIEDAENKEKYATKMSSLKQDLQALLGKE
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_CAUVC
Sequence: MTPDLTQSAITPARLTHLQRLEAESIHILREVAAECERPVMLYSIGKDSAVMLHLAAKAFYPSKPPFPLLHIDTTWKFRDMYALRDRIGSEMGFDLLVHKNPDAQARGINPFDHGSAVHTDLWKTEGLKQALSKYGFDAAFGGARRDEEKSRAKERVFSFRSSEHRWDPKNQRPELWNLYNTRKHPGESLRVFPISNWTELDIWQYIHLENIPIVPLYFAAERPVVERDGALIMVDDDRFRLRDGEVPQMRSVRFRTLGCYPLTGAVESTAATLPQVIQEMLLATTSERQGRVIDHDQSASMEKKKQEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RS10_NOSS1
Sequence: MATLQQQKIRIRLQAFDRRLLDTSCEKIVDTANRTNATAIGPIPLPTKRKIYCVLRSPHVDKDSREHFETRTHRRIIDIYQPSSKTIDALMKLDLPSGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MBN2A_TAKRU
Sequence: MALNIASIRDTKWLTLEVCRQFQRGTCSRSDEECKFAHPPKSCQVENGRVIACFDSLKGRCTRENCKYLHPPAHLKTQLEINGRNNLIQQKTAAAMLAQQMQFMIPSTTMQHVQTFPVNQGLGSSAGLSYTPYLTPMSHSMGLVPTDILPSTPVIVPGSPPVSVTAGSSSNQKLLRTDKLEVCREFQRGNCARGETDCRFAHPSDSPMIDTSDNTVTVCMDYIKSRCSREKCKYFHPPAHLQAKVKAAQHQANQTAVAAQAAATAAAMTQSTAKAMKRPLEATVDLAFPHSGLQPLPKRPALEKSNGSSSLFNPSVLHYQQALANAQLQQPAFFPTGSVLCMTPASSLGRS
What is the function of this protein?
Involved in pre-mRNA alternative splicing regulation.  RNA-binding protein that binds to 5'ACACCC-3' core sequence (By similarity).
What are the official names of this protein?
Muscleblind-like protein 2a, Tmbnl2a.
What is the protein family that this protein belongs to?
Belongs to the muscleblind family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.