PharMolix/UniProtQA huggingface dataset:
Protein: TUSD_PSEAE
Sequence: MKFAIALFDPPHSPAARRALRFSEAALAGGHEIVRLFFYQDGVHSASANVVSGQDEFDLPAAWRELVERNGLDAVVCIAAALRRGVLNAEEAERYGRPGANLGAPWELSGLGQLHEAAQSADRLVCFGGDR
What is the function of this protein?
Could be part of a sulfur-relay system.
What are the official names of this protein?
Sulfurtransferase TusD homolog.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2028_MYCTO
Sequence: MNQSHKPPSIVVGIDGSKPAVQAALWAVDEAASRDIPLRLLYAIEPDDPGYAAHGAAARKLAAAENAVRYAFTAVEAADRPVKVEVEITQERPVTSLIRASAAAALVCVGAIGVHHFRPERVGSTAAALALSAQCPVAIVRPHRVPIGRDAAWIVVEADGSSDIGVLLGAVMAEARLRDSPVRVVTCRQSGVGDTGDDVRASLDRWLARWQPRYPDVRVQSAAVHGELLDYLAGLGRSVHMVVLSASDQEHVEQLVGAPGNAVLQEAGCTLLVVGQQYL
What are the official names of this protein?
Universal stress protein MT2087.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
Protein: Y010_TREPA
Sequence: MGGKKSHFLGRRIEGTGRGVVPFVRKLSEVVKKITADGKKC
What are the official names of this protein?
Uncharacterized protein TP_0010.
Protein: FB294_ARATH
Sequence: MALPSSSWSEFLPELLNTVFHNLNDARDILNCATVCSSWKDSSSAVYYSRTFSPFLFISHLSSNEEIRFSDQFRVLSPGKLGFSGNQQAWVCGSTLGFLLTKPVTKSVTSLPPLISFEDVQRLLQSQAIIPDSEALKNFIKKAVSSTSLLDDEWVVLVIYNTDRKLAFCRRGDKQWTDLESVASSVDDIVFCNGVFFAIDRLGEIYHCELSANNPKATPLCSTSPFRYDSCKKYLAESDYDELWVVLKKLELNDDCDFETSFEIYEFNRETNEWTKVMSLRGKALFLSPQGRCIAVLAGERGFFKDNSVYFIDGDDPSVGGSGPQNLSVFEWESKQIMKIYQPRSWNCQMFWVTPTDVPQ
What are the official names of this protein?
Putative F-box protein At5g55150.
Protein: FOLD_HYDS0
Sequence: MNILDGKSLAKKIKHNIKQEVKHLERKPKLVVVLVGDDQASLVYVKNKVQACADVGFSSQLDMFEKDVEEDVLLNHIKSLNEQEDVDGILVQLPLPSHISMQKVIDTIDPSKDVDGFHPQNMGKLFSGDLENAFIPCTPLGIKLLLDEYNIDLKGKNVCIVGAGFIVGKPLSMLMLNYDATVSVCHKYTKDIVEYTKTADILISATGVPFLIKDYMVKEGAVVIDVGISKVNGKIVGDVDFESISQKASFITPVPGGVGPMTVATLLLNTLKAYKQRI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PCKA_BACP2
Sequence: MNSVDLKEDLQSLLSLENTHQNLSVPKLVEKILARDEGVLTSTGAVRATTGAYTGRSPKDKFIVKEESSEHKIDWGQVNQPISKEAFDRLYTKVVSYLKERDELFVFEGFAGADERYRMPITVVNEFAWHNLFAKQLFIRPDGSTPSSNEKPFTILSAPHFKADPETDGTNSETFIIVSFEKRTILIGGTEYAGEMKKSIFSVMNYLLPEQDILSMHCSANVGQEGDVALFFGLSGTGKTTLSASASRKLIGDDEHGWSGSGVFNIEGGCYAKCVNLSEEKEPQIYKAISFGSVLENVVLDEETREADYDDTFFTENTRAAYPIEMIDNIVKPSIAGHPSAIVFLTADAFGVLPPISRLTKEQAMYHFLSGYTSKLAGTERGVTSPETTFSTCFGSPFLPLPAHVYAEMLGKKIDEHGAKVFLVNTGWTGGGYGTGKRMNLAHTRAMVQAAIEGDLDNAEMITDDIFGLHIPLHIPGVPDEVLQPSKTWDDQEAYQEKAHFLANEFKKNFQKFSHAASDIEAKGGPLV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_MYCA9
Sequence: MRMRETQGAQGRGRNAPPFLRTILAYIALTKPRVIELLLVTTIPAMLLADRGDVNPLLILNTLLGGVMAAASANTLNCVADADIDKVMKRTARRPLAMSSVTTRNALIFGVVLGVGAFAWLWWTANLLSGLLAVATIAFYVFVYTLVLKRRTAQNVVWGGAAGCMPVMIGWSAVTNTIQWPALVMFAVIFFWTPPHTWALAMRYKEDYRAAGVPMLPVIATEEKVTKLILVYTWLTVLSTLALALAAGVIYAVVAFLAGVWFLAMAHQLYSGVRKGQPIRPLRLFLQSNNYLAVVFCALAVDSVVGWPTLFQL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABA_SALAR
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_BACTN
Sequence: MKTTPFTEKHIALGAKMHEFAGYNMPIEYSGIIDEHLTVCNAVGVFDVSHMGEFWVKGPQALAFLQKVTSNNVAALVPGKIQYTCFPNEEGGIVDDLLVYCYEPEKYLLVVNAANIEKDWNWCVSHNTEGAELENSSDNMAQLAVQGPKAILALQKLTDIDLSAIPYYTFTVGRFAGKENVIISNTGYTGAGGFELYFYPDAAEAIWKAVFEAGEEFGIKPVGLGARDTLRLEMGFCLYGNDLDDKTSPIEAGLGWITKFVEGKEFINRPMLEKQKSEGTTRKLVGFEMIDRGIPRHGYELVNEEGEGIGVVTSGTMSPTRKIGIGMGYVKPEYAKVGTEICIDMRGRKLKAIVVKPPFRK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: ASP2_STRGN
Sequence: MKNKLKILQIGSIDWSKEVVIPDNMDWYYFFSLTLRLAIKKVMEMEKINHFSAIIVDDLDLIPDLFLIESRIIPYTIFYSKKQQAIQEPIAFFLKRYCAQQIDLSDRPNLLRKLSKALFRGQYGDKMTPLDMVVSPGFKGRICHNGYENLELEGNFGSDFRPIVSWKYNIVASKKNPVEIWLEYEKDLSCELRLRIYNIQEGSAADLVRESVFSETDMEETIVLDNDFTSFLGITLEARGFGTLKIGAFHQRLTRYQFGKFVLGGKILKDSHRQEINYFFYPGDFKPPLVVYFSGYRRAEGFEGFGMMRGLGCPFLLISDQRLDGGVFYLGSDELEEGIRRIIQEHMELLGFSERELILSGISMGTYGAAYYGADFSPRAIILCKPLANLGTIAQRGRLRLPEVFPMALDILHRHTGGKDRENVMELDNRYWKKFKKADFSRTIFGLAYMKEEDYDPTAYEDLVQYLYPTETQLMSNGLSGRHNDDSTMVINWFMNYHRIILEKEFGRKK
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required to export GspB, a serine-rich repeat cell wall protein encoded upstream in the same operon.
What are the official names of this protein?
Accessory Sec system protein Asp2, Accessory secretory protein Asp2, Orf2.
What is the protein family that this protein belongs to?
Belongs to the accessory Sec system protein Asp2 family.
Protein: CRGN_XENTR
Sequence: MSQYSGKIIFYEGKCFTGRKLEVFGDCDNFQDKGFMNRVNSIRVETGAWICYDHPDFKGQQYILERGEYPDFHRWNGHNDHMGSCKPVRMHGERYRLELFEGCNFTGQCMEFCEDCPFLQGRGWNKNCVNACKVYGDGAWVLYEEPNYRGRMYIVERGDYRSFNDWQSQSANIQSVRRVVNYF
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin N, Gamma-N-crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: 3L228_OPHHA
Sequence: MKTLLLTLVVMTIVCLDLGYTLICFISSHDSVTCAPGENVCFLKSWCDAWCGSRGKKLSFGCAATCPRVNPGIDIECCSTDNCNPHPKLRP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin LNTX28.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PANB_STAES
Sequence: MKTLNHLNKMKASQQKISMVTAYDYPSAKQAQQAEIDMILVGDSLGMTVLGYDSTVQVTLNDMIHHGKAVKRGASDTFIVVDMPIGTVGLSDEEDLKNALKLYQNTNANAVKVEGAHLTSFIQKATKMGIPVVSHLGLTPQSVGVMGYKLQGDTKTAAMQLIKDAKAMETAGAVVLVLEAIPSDLAREISQQLTIPVIGIGAGKDTDGQVLVYHDMLNYGVDRHAKFVKQFADFSSGIDGLRQYNEEVKAGTFPSENHTYKKRIMDEVEQHD
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_STRGC
Sequence: MQNRPIIIGVTGGSGGGKTSVSRAILSNFPNEKIAMIEHDSYYKDQSHLTFEERIKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEPKDVFIVEGILVLEDQRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVIEQYLGVVKPMYHQFIEPTKRYADVIIPEGASNKVAIDLITTKIEKILKEARN
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZMY12_HUMAN
Sequence: MNVIYPLAVPKGRRLCCEVCEAPAERVCAACTVTYYCGVVHQKADWDSIHEKICQLLIPLRTSMPFYNSEEERQHGLQQLQQRQKYLIEFCYTIAQKYLFEGKHEDAVPAALQSLRFRVKLYGLSSVELVPAYLLLAEASLGLGRIVQAEEYLFQAQWTVLKSTDCSNATHSLLHRNLGLLYIAKKNYEEARYHLANDIYFASCAFGTEDIRTSGGYFHLANIFYDLKKLDLADTLYTKVSEIWHAYLNNHYQVLSQAHIQQMDLLGKLFENDTGLDEAQEAEAIRILTSILNIRESTSDKAPQKTIFVLKILVMFYYLMMNSSKAQEYGMRALSLAKEQQLDVHEQSTIQELLSLISTEDHPIT
What are the official names of this protein?
Zinc finger MYND domain-containing protein 12.
Protein: CXAT2_CONCE
Sequence: MPKLAVVLLVLLILPLSYFDAAGGQAVQWDRRGNGLARYLQRGDRDVRECQVDTPGSSWGKCCMTRMCGTMCCSRSVCTCVYHWRRGHGCSCPG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Cp20.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_ECOLC
Sequence: MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: CCND2_BOVIN
Sequence: MELLCGEVEPVRRAVPDANLLHDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAINYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQPSEKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEDVSSLTGDALVDLLAKITNTDVDCLKACQEQIEVVLLNSLQQYRQDQGDGSKSEDELDQASTPTDVRDIDL
What is the function of this protein?
Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
What are the official names of this protein?
G1/S-specific cyclin-D2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus membrane. Note=Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated into the nucleus through interaction with KIP/CIP family members.
Protein: G1PDH_SULIM
Sequence: MNVKEHVISLPRRVFVGHDIIYDISIYFSQLGITSPFLIVTGTKYTKKIADKVIENLPKDAKYEVIEIDTATLDDVYKVEEVVKKVNPNILLGIGGGKVIDVTKYAAFRNNLEFVSIPTSPSHDGITSPFASIKGLQKPVSVKAKEPLAIIADIEILSLSPRRLINAGIGDTIGKIIAVRDWRLAAKLRGEYYGDYTASLALMSAKHAFQCTKIINKDIKYGVRMLIEALISSGVAMGMAGSTRPASGSEHLFAHAVELLHPEGVLHGELVGLGTIIMAYLHGINWKIIRDRLKKIGFPVKAKDLGLSDEEVIKALTIAHTIRPERYTILGDRGLTWSSAEKIARVTKIID
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSL2_GIBZE
Sequence: MTIQSTANHQDGYLPAILCLHGAGTNATIFNLQARTIVRCLKHKFRFIFVNAPFESLPGPGVIPTFAEIRPYLRWHCDENAIQEFDVSPELVDNERRLVRSMISDKIEQEATGPSLGIVGVMAFSQGTRVATGLCLDPEFGSSIQFAIIIAGTFPALSLENPVSDSETTNLFSGINGNKHEQLQIPSVHVQGTMDPWGPESARLLKECWSADLAMVVKFHGAHQVPTSKKDAQAVAQAVLSCWDSAQT
What is the function of this protein?
Thioesterase; part of the gene cluster that mediates the biosynthesis of fusarielins F, G and H, decaketide compounds with 5 methylations and a decaline core that act as mycoestrogens as they stimulate growth of MCF-7 breast cancer cells (PubMed:22252016, PubMed:27983606).  The initial compound in the pathway is produced by the reducing polyketide synthase FSL1.  FSL1 lacks an active enoyl reductase (ER) domain and biosynthesis of fusarielins relies on the trans-acting enoyl reductase FSL5, before it is released through hydrolysis catalyzed by the thioesterase FSL2 (PubMed:22252016, PubMed:27983606).  Fusarielins F, G, and H have a C11=C12 cis double bond and is fully reduced between C10 and C11 and between C12 and C13.  FSL3 can be involved in the formation of the C11=C12 cis double bond by moving a hypothetical C10=C11 or C12=C13 trans double bond to form prefusarielin (PubMed:27983606).  Prefusarielin is oxygenated at C15 and C16 by the cytochrome P450 monooxygenase FSL4, resulting in fusarielin F, which subsequently is epoxidized into fusarielin G by the same enzyme (PubMed:27983606).  The final step in the pathway is a reduction of the carboxylic acid moiety to yield fusarielin H via a still undetermined mechanism (PubMed:27983606).
What are the official names of this protein?
Thioesterase FSL2, Fusarielin biosynthesis cluster protein 2.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: EFCB6_HUMAN
Sequence: MCKMAIIPDWLRSHPHTRKFTHSRPHSSPCRVYSRNGSPNKFRSSSTTAVANPTLSSLDVKRILFQKITDRGDELQKAFQLLDTGQNLTVSKSELRRIITDFLMPLTREQFQDVLAQIPLSTSGTVPYLAFLSRFGGIDLYINGIKRGGGNEMNCCRTLRELEIQVGEKVFKNIKTVMKAFELIDVNKTGLVRPQELRRVLETFCMKLRDEEYEKFSKHYNIHKDTAVDYNVFLKNLSINNDLNLRYCMGNQEVSLENQQAKNSKKERLLGSASSEDIWRNYSLDEIERNFCLQLSKSYEKVEKALSAGDPCKGGYVSFNYLKIVLDTFVYQIPRRIFIQLMKRFGLKATTKINWKQFLTSFHEPQGLQVSSKGPLTKRNSINSRNESHKENIITKLFRHTEDHSASLKKALLIINTKPDGPITREEFRYILNCMAVKLSDSEFKELMQMLDPGDTGVVNTSMFIDLIEENCRMRKTSPCTDAKTPFLLAWDSVEEIVHDTITRNLQAFYNMLRSYDLGDTGRIGRNNFKKIMHVFCPFLTNAHFIKLCSKIQDIGSGRILYKKLLACIGIDGPPTVSPVLVPKDQLLSEHLQKDEQQQPDLSERTKLTEDKTTLTKKMTTEEVIEKFKKCIQQQDPAFKKRFLDFSKEPNGKINVHDFKKVLEDTGMPMDDDQYALLTTKIGFEKEGMSYLDFAAGFEDPPMRGPETTPPQPPTPSKSYVNSHFITAEECLKLFPRRLKESFRDPYSAFFKTDADRDGIINMHDLHRLLLHLLLNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEKRPWRTDEAPQRLIRPKQKVADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPREFEKLWARYDTEGKGHITYQEFLQKLGINYSPAVHRPCAEDYFNFMGHFTKPQQLQEEMKELQQSTEKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHLLNSWGVSRHDNAINYLDFLRAVENSKSTGAQPKEKEESMPINFATLNPQEAVRKIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKDFCYKLTDNQYHYFLRKLRIHLTPYINWKYFLQNFSCFLEETADEWAEKMPKGPPPTSPKATADRDILARLHKAVTSHYHAITQEFENFDTMKTNTISREEFRAICNRRVQILTDEQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMATGDSAVAQRGSSVPDVSEGTRSALSLPTQELRPGSKSQSHPCTPASTTVIPGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISKEECQQLIIKYDLKSNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEAGAETPSFYSALLRIQPKIVHCWRPMRRTFKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFLRAFLQ
What is the function of this protein?
Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex (PubMed:12612053).  Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (Probable).
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 6, CAP-binding protein complex-interacting protein 1, DJ-1-binding protein, DJBP.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, cilium axoneme.
Protein: ARFB_METTH
Sequence: MLVELNLDAGNIISEDVHRIGILAVGSHLENHGPALPIDTDAKIASYVALEAALRTGARFLGVLYAASEFPYVKHGIHMDRDELVERELKPVLRKARRLLNLEAAVIVNGHGGNKLEDCMDDLEEELGLEIAWNNRIVEIEGPHAGSGELSAGLILGIADLRRLDECIPELYPEIGMIGLKEAREANREIDKAARICERDGVNPDPVLGQRILDDAVESVISDVKELLKIIQEF
What is the function of this protein?
Catalyzes the hydrolysis of the formamide of 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
What are the official names of this protein?
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase, FAPy deformylase, Formamide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the creatininase superfamily. FAPy deformylase family.
Protein: ASTE_YERP3
Sequence: MLDFLAITLSGKPPQVIQGETVNLKWQWLGEGILTLVPHRSYTQSVVISAGIHGNETAPIEILNQLVTDLLAGQLPLSVRLLVLLGNPPAIRKGKRYLSNDINRMFGGRYQHYTPSDETRRASTLEQRVMAFFQASHTSERLHYDLHTAIRGSYHPRFGLLPYQQTPYSAAMFRWLRDIELDALVMHTSAGGTFAHFSSERCQAASCTLELGKALPFGENQLSQFSAITQGLRSLVSDSALPARKTENMKYYRVVKSLLRQHPDFKLRVAEDTVNFTRFAQGTLLTEQPNDNYRVEHPYEWILFPNPHVALGLRAGMMLVKMCESELPIT
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: SYFB_BORPA
Sequence: MQFPESWLRSLVNPSIGTDELAHRLTMAGLEVEETEPAAPPFTGVVVARIVDIAPHPDADKLRVCQVDDGSGALLQIVCGAPNAAAGLTVPLARVGAELPGGMKIGVAKMRGVQSSGMLCSARELGLSQDHAGLLELPAALRPGTDIRAALDLDDTLFTLKLTPNRADCLSIFGVAREVAALTGTPLTAPAAEPVPVTIDHRLPVAIQAPDLCGRFAGRVIQGVNARAATPEWMKTRLERAGQRSVSALVDISNYVMLEVGRPSHVFDLDKIGGDLSVRWAREGETLELLNGQAVALDPKVGVVVAGEQVESLAGIMGGEATSVTLDTRNIYLEAAFWWPGAIAGRARRYKFSSEASHRFERGVDYASIPEHIELITRLILDICGGQAGPVDDQCVNLPVREPVRMRLARCHRVLGVAVERAEVAQIFTRLGLPFQEQGDDFVVTPPSYRFDIEIEEDLIEEVARVYGFERIPDVPPVARAKMHAQPEARRGAHAVRRLVAARDYQEVVNYSFVEAAWERDYAGNDNLVRLVNPIASHLSVMRSSLIAGLVAIVRHNANRKQSRVRLFELGRVFHRDPQLADGPLEVAGVRQPLMLAGVAWGGAVEEQWGVPHRQVDFYDVKQDVEALFGARADALRFVADRYPALHPGRSARIELDGQPIGWLGELHPQWTQQADLHHAPVVFELDFEALAERRLPAVRELSRQPAVVRDLALWVDAKLPAQAMLDTVAAAIARDPQLSVVQDAQVFDVWREKPVAGQTVTEKSLAFRFWLQDTEVTLDEARVADCIARIKDALVAAHNARQRA
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM50_PONAB
Sequence: MAARSVSGITRRVFMWTVSGTPRREFWSRFRKEKEPVVVETVEEKKEPILACPPLRSRAYTPPEDLQSRLESYVKEFFGSSLPSNWQDISLEDSRLKFNLLAHLADDLGHVVPNSRLHQMCRVRDVLDFYNVPIQDRSKFDELNASNLPPNLKITWSY
What are the official names of this protein?
39S ribosomal protein L50, mitochondrial, L50mt, MRP-L50.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL50 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GATZ_ECOL5
Sequence: MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVFAIADKVGFARERIILGGDHLGPNCWQQENADAAMEKSVELVKAYVRAGFSKIHLDASMSCADDSIPLAPETVAERAAVLCLAAESVATDCQREQLNYVIGTEVPVPGGEASAIQSVHITQVEDAANTLRTHQKAFIARGLAEALTRVIAIVVQPGVEFDHSNIIHYQAQEAQALAQWIEKTKMVYEAHSTDYQTQTAYRELVRDHFAILKVGPALTFALREAIFALAQIEQELIAPENRSRCLAVIEDVMLDEPQYWKKYYRTGFNDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQSGELSAIPHQLIMDKIYDVLRAYRYGCAE
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: FMT_CORDI
Sequence: MRLIFAGTPEPAVVVLSRLLESEHEVVAVLTRPDARRGRGRTLHPSPVSELAQQHGIEVLTPATIKPNTPDGDAFRARLTELAPDCVPVVAYGNLITEDLLQAVPHGWINLHFSLLPRWRGAAPVQAAIAAGDTSTGATTFRIDKGLDTGQILGVIHEPIQSTDTADDLLTRLAYSGADLLVNTMDNLAQGIATYSEQIGTATYAPKITTEDARIQWTHPAEAVDKHIRAVTPGPGAWSLLGDQRFKIGPVSVAEESDLQPGHMRIEKNRVLVGTGDLNIELDQIQPQGKKRMKASDWARGLQNTEGLVLS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: TGT_LEPCP
Sequence: MLNFDLLTTEGHARRGRLTLNHGVVETPIFMPVGTYGTVKGVMPRDLETMGAQIILGNTFHLWMRPGQDVMAQFGGLHRFENWTRPILTDSGGFQVWSLGEMRKISEEGVRFASPVNGDKLFLTPEVSMQIQTVLNSDIVMQFDECTPYWQGAKNVGHITTEKEARVSMELSLRWAARSKAEFARLGNPNALFGIVQGGMFESLREESLNALVELDFPGYAVGGVSVGEPKDEMLRIMNHTPHLLPADKPRYLMGVGTPEDLVDGVACGVDMFDCVMPTRNARNGHLFTRYGDLKIRNARHKADERPLDETCSCQACKGSTLPDGRVTGGFSRAYLHHLDRCGEMLGPMLASIHNLHYYLNLMREVREALDAGRFEAFRAQFKADRARGV
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PRVA_CAVPO
Sequence: LLNAEDIKKAVGACAAAESFDHKKFFQMVGLKKKNREEVKMVFQILDKDKSGFIEEEELKFILKGFSADARDLSDTETKRMMAAGDKDGDGKIGA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin alpha.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.