PharMolix/UniProtQA huggingface dataset:
Protein: B2I5_SICPE
Sequence: WIMGHMVNAIEQVDEFLDLGANAIEFDVDFDDDGVAKYTHHGIPCDCGRLCTKYAVFTEYLDYVRQVTTPGDPKFRKELVLLALDLKLQRIPSEKAYAAGVDVATKLLDHYWMRGWNGGRAYILLNIPLVEDYEFIRAFKDTLRKEGHEQYNAKVGINFTGNEDLDEIREVLEKLGEDEHIWQADGITSCFPRGTERLKKALEKRDTPGYKYISKVYAWTLVRSSIMRRSLRLGVDGVMSNYPDRVVKVLKEKEFSDKFRLATYADNPWEKFTPI
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin SpeSicTox-betaIIA2v, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TX4_SELPU
Sequence: MKASLFAVIFGLVVLCACSFAEDQFASPNELLKSMFVESTHELTPEVEGRYCQKWMWTCDAERKCCEDMACELWCKKRLG
What is the function of this protein?
Probable ion channel inhibitor.  Shows insecticidal activity when injected into mealworms.
What are the official names of this protein?
U4-theraphotoxin-Spl1a, U4-TRTX-Spl1a, Orally active insecticidal peptide-4, Toxin OAIP 4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 30 (phrixotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GBP6_HUMAN
Sequence: MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF
What is the function of this protein?
Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens, such as bacterial pathogens Listeria monocytogenes and Mycobacterium bovis BCG as well as the protozoan pathogen Toxoplasma gondii (By similarity).  Confers protection to several pathogens, including the bacterial pathogens Listeria monocytogenes and Mycobacterium bovis BCG as well as the protozoan pathogen Toxoplasma gondii (By similarity).
What are the official names of this protein?
Guanylate-binding protein 6, GTP-binding protein 6, GBP-6, Guanine nucleotide-binding protein 6.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle.
Protein: PSAB_PHAVU
Sequence: MALRFPSFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFETWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNGDLYTGAIFLLILSTISLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPGSRGEYVRWNNLLGILPHPEGLGPFFTGQWNLYAQNPDSNNHIFGTPQGAGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFIFLVAGHMYRTNFGIGHSIKDLLEVHTPPGGRLGRGHKGLYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNKDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDILLSSTNSPAFNAGRSIWLPGWLNAVNENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNISQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RR14_LEPVR
Sequence: MAKKSLIYREKKRQKLEKKYHLIRRSSKKEISQIPSLSEKWKIHGKLQSPPRNSAPTRLHRRCFSTGRPRANYRDFGLSGHILREMVQACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PIG11_UROFA
Sequence: MNPCSSNCSCGASCTCSGCSSHKK
What are the official names of this protein?
Planta-induced rust protein 11.
Protein: AZOR1_CLOPE
Sequence: MKKLLYITVNSKPEKLSSSKTIGRAFISRFVELNPEFEIEEVDLYKDFIPRLEHKHFSGRSSVVDCETASIDAKTKEEVKRIIELSEQFKNADLYVIAAPLWTLSFPAPLKEYIDCVVQNKITIKVTPEEVKGLLDDKQREMVYIQSSGGEIPWLTKGIFNKGLNYVEDVMKFLGIKKFHQLLVDGTGFSIEEKFKAEDKAVEKIDNVIKDIHFSNKG
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 1, Azo-dye reductase 1, FMN-dependent NADH-azo compound oxidoreductase 1, FMN-dependent NADH-azoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: CTU2_SCHPO
Sequence: MQNTALDNSADSKCSKCDNKATVLTKSDAVCDSCFVRRIENKIRRQFELVRPNLQGRKSKRAMLAISGGISSMAMLETANYLSKYRDDNYRPMFDELLAVHFQWGTDSAVAKTIEESISKNYPKCPFKVIGEAELLNRTIATDSRGNIEINADNEKFNPEVISSLASRQDLLYRIRDKLLVSYARKANCDTIVFGDSGTTIAARVLELVAEGRGFAIPWYTSVCSKLPNCDTFLLRPLREVLSSDLKSYMNIKGLAFCDSLIEARPNTIHGVTESYFSSLNDTFPSLVSTVVKMSSKLHVPSTEAICTICNLPMQEDAETWLQKTTVEHPDSVEGIKNQNVCYGCSVSLKSLKGTLHIPDIEKEGI
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with ctu1 that ligates sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ORTH3_ARATH
Sequence: MTPATQYPCDPEGVCMRCKSMPPPEESLTCGTCVTPWHVSCLLSPPETLSATLQWLCPDCSGETNPLPVSGVAAGYGSVGSDLVAAIHSIEADETLSAEEKAKKKQQLLSGKGVVDEDDEEEKKKTSKGKKPIDVLSHFECSFCMQSLQKPVSVRVLFALALMLVWFLESTPCGHNACLKCFLKWMGQGHRSCGTCRSVIPESMVTNPRINLSIVSAIRLARVSEKADARTSKVVHYVDNEDRPDKAFTTERAKKTGNANASSGKIFVTIPRDHFGPIPAENDPVRNQGLLVGESWKGRLACRQWGAHFPHVSGIAGQASYGAQSVVLAGGYDDDEDHGEWFLYTGSGGRILKGNKRTNTVQAFDQVFLNFNEALRLSCKLGYPVRVVRSTKDKRSPYAPQGGLLRYDGVYRIEKCWRIVGIQMCRFLFVRCDNEPAPWTSDEHGDRPRPLPNVPELNMATDLFERKESPSWDFDEGEDRWRWMKPPPASKKAVKNVLDPEERKLLREAIKSANPNTMRARLLKEFKCQICQKVMTNPVTTPCAHNFCKACLESKFAGTALVRERGSGGRKLRSQKSVMKCPCCPTDIAEFVQNPQVNREVAEVIEKLKKQEEEENAKSLDEGQCSGTSHEEEDDEQPKKRIKLDTDAEVSATVVESDMK
What is the function of this protein?
E3 ubiquitin-protein ligase.  May participate in CpG methylation-dependent transcriptional regulation (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase ORTHRUS 3, Protein VARIANT IN METHYLATION 5, RING-type E3 ubiquitin transferase ORTHRUS 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: THNS2_DANRE
Sequence: MRYCSTRAGVQGRSFRDVLFSGYAADGGMFMPENLPSLSAETLRSWRRLSYRQLLCEVCELFIPEQEIPREQLEGLVSSALSSFSVPDAVRLVQLKDSLSILELFHGETLAFKDLAMSCTAHFLQYFLRRDRQRATILVGTSGDTGSSAIRSVLGLREVDIVVVFPRGRITKIQELQMTTSVAENVHVFAADGTSDDIDVPLRKLFADADLVQRHRLMSLNSVNWSRIMVQTAHFLFAYLQLTPSLPEGDTLPVLEVLVPTGGAGNITAGIIVKRMGVPLRLVAMVNANDIVHRTVQSGDFSMSSSVTQTLAPAIDIQDPYNMERVFWLLSGGDGLMVKSLMEEFQKTHKLSLPASLHQQLSEVLSSGSVSDDGILEAMRRCWQDNHYLICPHTAVAVWRHYQSPVRPGESRCCIATASPHKFQQAVQRAGLTLELPESLQVLDQLETRCADLKCSDDWEETLRRHIESISSRRNS
What is the function of this protein?
Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates.  Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity).
What are the official names of this protein?
Threonine synthase-like 2, TSH2.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
Protein: YH019_YEAST
Sequence: MRCLRKRQTIYAYSSSLTVLYLTQGKDWYCNCGSSTFKYSTFRPLHVQYGISKSMLTNLSRGVTWEVCWSCTCLYSSSSLGPVRKGGGFIEVFISSCRRSYSSWLKRGNSATMDAHVFGSSSSLLYCELLFVLCSRCPFMVCISQRRKSSLKLNTTLPMFALNLICLLRSILYSWKTFVRGILTFSFDVELVGLKFV
What are the official names of this protein?
Putative uncharacterized membrane protein YHL019W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ORF23_TTVV5
Sequence: MSWRPPVHDAPGIERNWYEACFRAHAGSCGCGNFIAHINLLAGRYGFTGGPPPPGGPPPGTPQVRASRNSPAAPQQPPALPWHGDGGEGGAAGPPGAGGDAAADAHLGDEELADLLDAIEDDAQCSNRRSKTRARRTDGPPTPIDTLEEYKWRTRNKWDPAGCSTPLTGEGAILARELSNACTRNLSTMKAILHNQKDLESFLQQRQQRESSESPKKAHIQRKKGRKPLQKSRRRRRQYSSSSDDSESSGSSSSSSNSSPEKCSKRKRVST
What are the official names of this protein?
Probable protein VP2, ORF2/3 protein.
Protein: SKI16_ARATH
Sequence: MGLEDAGDLVLHIVLSKIGPENTARVACVSKRLKVSASEESLWSIFCSNDLNISTPLDPHGDPAPSFKRAYQLWRESFRMYPWNLVKRVRLCWDNLKQWLTLNFPEAKATLRKGVTEDDLQEFETSLKVKLPLPTRLLYRFVDGQELSSPNGLDGSLGLIGGYSAYSHDVNVYLLPLKEVMRETKESFMRDLGFSSRLDLIVMAASVVASLKIFLLDCTTGQLFTGTSNRQLLPCVPDALVRSVHDTNGDQQQDAMLLWLEEHGRRLQTGTINVRQQNNVKSISLFPEIPPLCSVSVTNGVQVRASSVFIPEISNLRDQPPAYWYAYSIRMSLMPEGCILNGTHHSSCQLYWRHWVIRADNEVIDNVNGEAVIGKYPLLQAGEEEFVYESCSSFPTTAGSIDGSFTFVPGSLRDPKGSQFEVKVVEFPLELPDYIF
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
F-box protein SKIP16, SKP1-interacting partner 16.
Protein: AAEA_SALTY
Sequence: MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITHVNVHDNQLVKKDQVLFTIDQPRYQKALAEAEADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYAGEFITRGSTAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSVAAGVTNASSTSDAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWPAGTTATVVITGKQDRDASQDSFFRKLAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SPSA3_ORYSJ
Sequence: MYGNDNWINSYLDAILDAGKGAAASASASAVGGGGGAGDRPSLLLRERGHFSPARYFVEEVITGYDETDLYKTWLRANAMRSPQEKNTRLENMTWRIWNLARKKKELEKEEANRLLKRRLETERPRVETTSDMSEDLFEGEKGEDAGDPSVAYGDSTTGNTPRISSVDKLYIVLISLHGLVRGENMELGRDSDTGGQVKYVVELAKALSSCPGVYRVDLFTRQILAPNFDRSYGEPVEPLASTSFKNFKQERGENSGAYIIRIPFGPKDKYLAKEHLWPFIQEFVDGALSHIVKMSRAIGEEISCGHPAWPAVIHGHYASAGVAAALLSGALNVPMVFTGHFLGKDKLEELLKQGRQTREQINMTYKIMCRIEAEELALDASEIVIASTRQEIEEQWNLYDGFEVILARKLRARVKRGANCYGRYMPRMVIIPPGVEFGHMIHDFDMDGEEDGPSPASEDPSIWSEIMRFFTNPRKPMILAVARPYPEKNITTLVKAFGECRPLRELANLTLIMGNREAISKMHNMSAAVLTSVLTLIDEYDLYGQVAYPKRHKHSEVPDIYRLAVRTKGAFVNVPYFEQFGVTLIEAAMHGLPVIATKNGAPVEIHQVLDNGLLVDPHDQHAIADALYKLLSEKQLWSKCRENGLKNIHQFSWPEHCKNYLSRISTLGPRHPAFASNEDRIKAPIKGRKHVTVIAVDSVSKEDLIRIVRNSIEAARKENLSGSTGFVLSTSLTIGEIHSLLMSAGMLPTDFDAFICNSGSDLYYPSCTGDTPSNSRVTFALDRSYQSHIEYHWGGEGLRKYLVKWASSVVERRGRIEKQVIFEDPEHSSTYCLAFKVVNPNHLPPLKELQKLMRIQSLRCHALYNHGATRLSVIPIHASRSKALRYLSVRWGIELQNVVVLVGETGDSDYEELFGGLHKTVILKGEFNTSANRIHSVRRYPLQDVVALDSPNIIGIEGYGTDDMRSALKQLDIRAQ
What is the function of this protein?
Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate.  Involved in the regulation of carbon partitioning in the leaves of plants.  May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf.  Plays a role for sucrose availability that is essential for plant growth and fiber elongation (By similarity).
What are the official names of this protein?
Probable sucrose-phosphate synthase 3, Sucrose phosphate synthase 3F, OsSPS3F, UDP-glucose-fructose-phosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family.
Protein: AROQ_HAEIG
Sequence: MSQTHRILLLNGPNLNMLGAREPKHYGSISLESIEEKIQTLATQHNVKVECFQANSEEKLINKIHESFQQVDFILINPAAYTHTSVALRDALLAVSIPFVEIHLSNVHKREPFRHHSYFSDVAEGVICGLGAKGYEFAFLFAMDYLAKK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RECA_EHRCR
Sequence: MSDSKNLNQERQKALDSAISQIEKAFGRGAIMKLKQGAIEKIDSISTGSIALDTALGIGGFPKGRIVEIFGPESSGKTTLALHVIAESQKKGGNCAFIDAEHALDIMYARKLGVNTGDLIVSQPDTGEQALHIVEYLVCSGAIDVIVVDSVAALTPRAEIEGDMGDQHMGLQARLLSHALRKLTSIVSKANCVLIFINQIRMKIGVVYGNPETTTGGNALKFYSSVRLDIRKVSAIKDKDVIIGNQTKVKVVKNKVAPPFKQVDFDIMYNEGISKVGEIIDMGVKLNIIEKAGSYYSYNSVRLGQGKENAKSYLKANCDTAHEIEQKIRSILASDNEVSCFNAEVNDNLHEVEETVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_YERPS
Sequence: MPKIKTVRGAAKRFKKTANGGFKRKHANLRHILTKKATKRKRHLRPKGLVSKNDLGLVVACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PSBC_CICAR
Sequence: MKTLYSLRRFYHVETLFNGTLALTGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKASYFGGIYDTWAPGGGDVRKITNLTLSPSIIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLGALAVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MPTA_METMJ
Sequence: MELPDVQSSLPEVRINLTRVGVKNVQKLVEVARPGKRPVIFISNFDVFVDLPGSLKGANLSRNFEVIDDVLQQAIDGDVNEIEELCSAVARKLLDRHEYAERTEVRMRSKFMVRRETPVSETSCHEVVNVHAKAIAQRNEGDPIIRKSIGAEVTGMTACPCAQNIMKDHALHVLENLGVAEDKIEAFFNEVPMATHNQRGRGFLCIEIDDDQHISLEKIIKILKDSMSARIYELLKRGDESYVVMEAHKNPRFVEDCVREMARKVIAQFHDLPGDSVVTIKQTNEESIHQHNAYAERKATIAELVSEMDKGTL
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA, GTP cyclohydrolase IV.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: RAB21_RAT
Sequence: MAAAGGGAAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDDEPQAQSGSGGCCSSG
What is the function of this protein?
Small GTPase involved in membrane trafficking control (By similarity).  Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (By similarity).  As a result, may regulate cell adhesion and migration (By similarity).  During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (By similarity).  Involved in neurite growth (PubMed:19745841).  Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (By similarity).  Modulates protein levels of the cargo receptors TMED2 and TMED10, and required for appropriate Golgi localization of TMED10 (By similarity).
What are the official names of this protein?
Ras-related protein Rab-21.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network. Golgi apparatus membrane. Early endosome membrane. Cytoplasmic vesicle membrane. Cleavage furrow. Cell projection, neuron projection. Note=Colocalizes with ANKRD27 and VAMP7 in neurites (PubMed:19745841). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (By similarity). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (By similarity).
Protein: FPG_RICCK
Sequence: MPELPEVETLKNSLKDKLIGLIIKNIELKRDNLRYNLSPLLTTEILNTNILNVRRRAKYLIIDFGNYYSLVIHLGMSGRFTVQPANYKIQKHDHVIFDLNNCEKLIFNDTRRFGMVYSFKTNFLEEKFFYNLGIEPLSDLLTLEYLKSKLITRTIAIKNLIMDNKIIVGVGNLYASESLHLARIHPHKLGRNLKDDEIENLIKSIREVLTKAITAGGTTLKNFVNGDSKPGYFTQQLRVYGREGQKCFNCSSTILKTKNSGRSTFYCKTCQYT
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: A1MA1_LOXDE
Sequence: WIMGHMVNAIAQIDEFVNLGANSIETDVSFDKNANPEYTYHGIPCDCGRTCTKSEKFNVFLQGLQKATTPGDSKYQEKLVLVVFDLKSSSLYDNQASDAGKKLAKSLLQNYWKNGNNGGRAYIVLSIPNLAHYKLITGFKETLKTEGHPELMEKVGYDFSGNDDIDQVAKAYKKAGVTGHVWQSDGITNCLPRGLDRVRQAVANRDSSNGFINKVYYWTVDKRSTTRGALDAGVDGIMTNYPDVIAVVLSESAYKSKFRIATYEDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LdSicTox-alphaIB3ai, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EXGD_ASPOR
Sequence: MPSHSRSRDRYRSERDPSRRYREVYDDDDDDDFDYHPRERRRYRRDDYQHDIRSHESPNYNDDLNEYDAAAEDPAVPLRSHDVEGRRRERSRAGESPIASPSRRDRNRGGEEYRRHGTYGDGGSPTRAMRDRRHRSRDGQRARPRDMDREARRQRRRERARGAAAMKHKSSDSTNSGSHLLSADALAKLRSHYDEEDQRERSQEQEQPRMESKRQRKRPIVGDEPQALAPFPDETPRGQSKGRIVSGAYLEEGHPEMEVRHRGGGGPAMEARWRKEGNWDGTMEGSDAQPPFWKRKKWWIVIGVLVVVLAIVIPVAVVMSKKHGHDDDKSGSSSSVDNSDSPYISSLDGLSHDSIPESAQGSILDPWTWYDTRDFNLTFTNETVGGLPIMGLNSTWDDSTRPNDNVPPLNESFPYGSQPIRGVNLGGWLSIEPFIVPSLFENYSSKDRIIDEYTLCKKLGSSAASTIEKHYADFISEQDFIDMRDAGLDHVRIQFSYWAVTTYDDDPYVAKISWRYLLRAIEYCRKYGLRVNLDPHGIPGSQNGWNHSGREGVIGWLNGTDGQLNRQRSLDFHNQISQFFAQPRYKNVVTIYGLVNEPLMLSLPVEDVLNWTTDATKLVQKNGISAYVTVHDGFLNLSKWKQMLKDRPDRMFLDTHQYTIFNTGQIVLNHTDRVKLICNDWYNMIKEINTTSAGWGPTICGEWSQADTDCAQYLNNVGRGTRWEGTFAIGDSTVYCPTADTGPTCSCASANAPPADYSDGYKKFLQTYAEAQMSAFGTAQGWFYWTWHTESAAQWSYKTAWKNGYMPKKAYAPDFKCGDDIPSFGDLPEYY
What is the function of this protein?
Glucosidase involved in the degradation of cellulosic biomass.  Active on lichenan (By similarity).
What are the official names of this protein?
Probable glucan 1,3-beta-glucosidase D, Exo-1,3-beta-glucanase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: NUSB_STAAE
Sequence: MSRKESRVQAFQTLFQLEMKDSDLTINEAISFIKDDNPDLDFEFIHWLVSGVKDHEPVLDETISPYLKDWTIARLLKTDRIILRMATYEILHSDTPAKVVMNEAVELTKQFSDDDHYKFINGVLSNIKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.