PharMolix/UniProtQA huggingface dataset:
Protein: RODZ_SALTY
Sequence: MNTEATHDQNEAQTTGVRLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPSDLASTFLRGYIRSYARLVHVPEEELLPGLEKQAPLRAAKVAPMQSFSLGKRRKKRDGWLMSFTWLVLFVVVGLTGAWWWQNHKAQQEEITTMADQSTAELNADKDSGQSVPLDTGAATSQDTTPAQTAPAPATPVDSTAATQTPAPTAAATQNTVVAPSQANVDTAATSAAPAATETPSALPTSQAGVAAPAADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEPTPAQ
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: TM164_BOVIN
Sequence: MSRYSYQSLLDWLYGGVDPSFAGNGGPDCAAFLSWQQRLLESVVVLTLALLEILVALRHILRQTKEDGRGGRGCQPEQVTQRPEEGKESLSKNLLLVALCLTFGVEVGFKFATKTVIYLLNPCHLVTMMHLPFELEIYYIQHVMLYVVPIYLLWKGGAYTPEPLSSFRWALPSTGLMFFYHFSILQILGLVTEVNLNNMLCPAISDPFYGPWYRIWASGHQTLMTMTHGKLVILFSYMAGPLCKYLLDLLRLPAKKID
What is the function of this protein?
Positive regulator of ferroptosis.  Selectively mediates ATG5-dependent autophagosome formation during ferroptosis, rather than during starvation, and regulates the degradation of ferritin, GPX4 and lipid droplets to increase iron accumulation and lipid peroxidation, thereby promoting ferroptotic cell death.
What are the official names of this protein?
Transmembrane protein 164.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MYX3_CROVV
Sequence: YKRCHKKGGHCFPKTVICLPPSSDFGKMDCRWKWKCCKKGSVNNA
What is the function of this protein?
Cationic peptide that possesses multiple functions.  It acts as a cell-penetrating peptide (CPP), and as a potent voltage-gated potassium channel (Kv) inhibitor.  It exhibits antimicrobial activities, hind limb paralysis, and severe muscle necrosis by a non-enzymatic mechanism.
What are the official names of this protein?
Myotoxin-3.
What is the protein family that this protein belongs to?
Belongs to the crotamine-myotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL24_DICT6
Sequence: MDIKKGDLVLVISGKDKGKRGKVISVLPSEEKVIVEGVNIVKKHTRPNAKMRQGGIIEKPAPLYRCKVMLICPHCNQPTRIKHTFLEDGRKVRVCSKCKEIIDRV
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: IF2_FRACC
Sequence: MAGKARVHELAKELGVDSKTVLAKLKDLGEFVKSASSTVEAPVVRKLKEAFPADGAPTSPGRATSRPGPPGGGARPTPPSRPGLAPRPGPRPVPGRPGPLGRPGPATPAPSPSPASPPLPASPVQASPVQASPVQASPTSAPAAPRPAAASAVPAPPMPSVPSAPSGPRPGPNAPRPGAPQGGGRPRPGTPVPPSGPTAGGPTAGGPTAGGPTAGGPRPGPRPGPRSAAPGNNPYTTPSAGPRPSAGPRPSAGQSGPPSTPTPRPSAPRSGTPRPGTPRPGGPRPGGTGAGGPRPTPGGMPPRPGGPRSGAGGGMPPRPGGTGGPRPNANMFQPRPAGGPPGRPGGGGAPGRPGGGGAPGRPGGGGGPRPGGFAGRGGAPGRPGGGGGGGGAPGRPGGGGGGGGAPGRPAAGGRGRGGTTAGAFGPGGRGRPGRQRKSKRAKRQEWESGLEAPRMGAMVPRGNGQAIRLPRGASLADFADKIDANPGALVQVVFTQLGEMVTATQSCTDETLQLLGVTLGYEVQIVSPEDEDKELLESFDLSFGGEYGDDVELSSRPPVVTVMGHVDHGKTKLLDAIRSTDVVGGEAGGITQHIGAYQVRAKVDGDERPITFIDTPGHETFTAMRARGAQVTDIVVLVVAADDGVKPQTIEALNHAQAAGVPVVVAVNKVDKEGADPAKVRGQLTEYGLVAEEYGGDTMFVDVSARNRTNIDGLLEAIVLTADASLDLRAPTEVEAQGVAIEGRLDRGRGPVATVLVQRGTLRVGDSVVAGEAFGRVRAMLDEHGGQVVEAGPARPVQVLGFTSVPDAGDNFLVVPEDRVARQIAERRQARERNAELALSRGRPTLETILERMKEGEKTQLNLILKGDVSGSVEALEDALLKIDVGDEVGLRIIDRGVGAITETNVMLASASDAIIIGFNVRPQGKATELADREGVEVRYYSVIYQAIEDIENALKGMLKPVYEEAQLGTAEVREVFRVPRIGNVAGSLVRSGVIRRNTKARLIRDGVVVADNLTVESLKRFKDDATEVREGYECGIGLGSFNDIKIDDVIETFEQREVPRA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_BACFR
Sequence: MIKVGINGFGRIGRMVFRAAVKNFGNDIQIVGINDLLDAEYLAYMLKYDSVHGRFEGEVAVEDGALIVNGNKIRLTAEMDPANLKWNEVDADVVVESTGFFLTDETARKHIQAGAKKVIMSAPSKDSTPMFVYGVNHTSYAGQDIISNASCTTNCLAPIAKVLNDKFGIVKGLMTTVHAATATQKTVDGPSKKDWRGGRGILENIIPSSTGAAKAVGKVLPVLNGKLTGMAFRVPTSDVSVVDLTVVLEKAATMAEINAAMKEASEGELKGILGYTEDAVVSTDFRGCANTSIYDSKAGISLDSNFAKVVSWYDNEWGYSNKVCEMARVIAAK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDI_SALPA
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: MNMA_PARXL
Sequence: MSKQKVVVGMSGGVDSSVTAWLLKEQGYDVVGLFMKNWEDDDDSEYCSTRQDWIDVVSVADLIGIDVEAVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGAQTIATGHYARVRENNGRFELLKALDHTKDQSYFLHRLNQAQLSKTLFPLGEIPKTRVREIAEQIALPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTTEGKVVGEHIGLAFYTFGQRKGIGLGGSKDGSGEPWFVAGKDIPSNTLYVAQGHDHPWLLSHTLSAGNTSWVAGEPPADGFACGAKTRYRQADAPCTFSSAGAGEGLFELNFDVAQWAVTPGQSAVLYDGDVCLGGGIIEHAVTGQPATRQPQKAALLTAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDPP1_XENTR
Sequence: MEEHRKLLPNATVEEYNYFEEDFVFQGLSWKKRQEFAEDTSFLSPFDKALQSKWEEKMNEGLFRYPLRNVQTKILPGSVSYVAQLNIQRSINRRKPEDIWSVQQKFNPNQFNYNKIKSEEIVFQMIRSEAEHSVDSHIVQGSMVNGMGSSECKSGSTPQGSCTLECKSSCTLVVINVSPLEFGHVLFMPDPSLCLPQILTENLMLFGMESVFLSSHPGFRVGFNSLGGFASVNHLHLHGFYLDHELLIESSCSKPLCPEINFHLVTHFPAPGFLFYTDGKDLKSTAQKICKVTDFLVAKNIAHNLFVTRGSNPDTGKVSEDRNGIRVIIWARKPSFGAKEVSAFNVALCELAGHLPVKNQEDFISITEDSVIAIIHSCLLADDEFTQLSLDLVQHLRKQ
What is the function of this protein?
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
What are the official names of this protein?
GDP-D-glucose phosphorylase 1.
What is the protein family that this protein belongs to?
Belongs to the GDPGP1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTNI_ECOLI
Sequence: MPRFAANLSMMFTEVPFIERFAAARKAGFDAVEFLFPYNYSTLQIQKQLEQNHLTLALFNTAPGDINAGEWGLSALPGREHEAHADIDLALEYALALNCEQVHVMAGVVPAGEDAERYRAVFIDNIRYAADRFAPHGKRILVEALSPGVKPHYLFSSQYQALAIVEEVARDNVFIQLDTFHAQKVDGNLTHLIRDYAGKYAHVQIAGLPDRHEPDDGEINYPWLFRLFDEVGYQGWIGCEYKPRGLTEEGLGWFDAWR
What is the function of this protein?
Catalyzes the isomerization of 2-oxo-tetronate to 3-oxo-tetronate.
What are the official names of this protein?
2-oxo-tetronate isomerase, 2-dehydrotetronate isomerase, Glyoxylate-induced protein YgbM.
What is the protein family that this protein belongs to?
Belongs to the hyi family. OtnI subfamily.
Protein: TXK02_LYCSI
Sequence: MFSTSDQVSKMNSRILSALLILGIATCVIAGGFCPKSRHPQCNLSYKINDCCAQSDCRVGSVCCVEGCGNVCRAESDTPLGEKFVDGSECKHGHVFPKKWYQFWWRV
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
U20-lycotoxin-Ls1b, Toxin-like structure LSTX-Q2.
What is the protein family that this protein belongs to?
Belongs to the venom protein 11 family. 02 (wap-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIPM_MOOTA
Sequence: MPAETWRLLDTGVSDPYTNMAIDEAILLEHREGKTPPTLRFYAWSPPTISLGYFQQLEKEIDLEAVKERGLGLVRRLTGGRAVLHDDEVTYSVVAREDHPLMIGGIRPSYLRLAKALAAGLRELGAPVEIASGRKGGREEHTTAACFDAPSWYEITCGGRKLVGSAQTRKGGVVLQHGSIVLTLNGDDLFAVLKMPSEAVRQRLLAKFYHQACGLEEVLGRRVEAGVIKENIVRAFTRLYAVEFVPGGLTEGEKGRLKELRAKYAAADWLKRR
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
What are the official names of this protein?
Octanoyltransferase LipM, Octanoyl-[acyl-carrier-protein]:[GcvH] N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipM family.
Protein: UPPP_PROM3
Sequence: MGPLFSSMILLASTSELLAACWRNLVLGVVQGLTEFLPISSTAHLKVVPMLVGWGDPGVSATAVIQLGSILAVIVYFKRDLAEVLKGIALAFKHGQWREPKARLGLAIAIGTMPILLAGMAIKLFWPGYEASSIRSLPSIAVVSIVMALLLALAERIGPRLKQMHLVKGRDGFVVGLAQALALIPGVSRSGSTLTASLFDGWQRQDAARFSFLLGIPAITLAGLVELKDAFAELSLEGVLPLLVGIVSAAFVSWLAIDWLLKYLQRHSTWIFVAYRLLFGVLVLAWWLSDTSN
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRB_LEPIN
Sequence: MASVFKIHSAYQPAGDQVKAIQNIADSFQKGEKKVTLVGVTGSGKTFTMAQVIQNLGLPTLVLSHNKTLAAQLFREFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDSSINEEIDKLRLRATSSLLEREDVVIVSSVSCIYGLGSPEEYTNSVVALKVGDTIERDTVIRKLLHIQYNRNDLDFSRGNFRVRGDSIEIYPAYHTDGIRIEFFGDEIDSISRINPVTAQTIFKLEKAYIYPAKHFITSGPKVKEAVENIRAEVDAQTDFFRKNNKLLEAERILSRTNYDMEMLQEMGYCNGIENYSRHLTGRKPGERPACLIDYFQGEFLLIVDESHVTIPQIGGMFAGDRARKQTLVDFGFRLPSALDNRPLNFQEFETLTPRTLYVSATPAEYEIEKSSKVVEQIIRPTGLLDPIVDVRPTKNQIEDLLVEIRKRIDAGERVLVTTLTKKMSEDLTDYYEEIGLKVAYLHSEVETLDRVGIIRDLRKGIYDVLIGINLLREGLDIPEVSLVAILDADKEGFLRNYKSLIQTIGRAARNVNGTAILYADKTTDSMAKAIEETKRRRKIQEDHNLKFGITPLTIKKEVGDIIEREEKERTSEDLVLEDVEKKFNSKKFPNKEVLKEKLREEMMKAAKELDFERAAILRDKMLSIQTEDSSAKN
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMEB1_HUMAN
Sequence: MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRRNQVEQGEEQFLYTLTDLERQLEEQKKQGQDHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED
What is the function of this protein?
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids.  Binds also to the transferrin receptor promoter.  Essential auxiliary factor for the replication of parvoviruses.
What are the official names of this protein?
Glucocorticoid modulatory element-binding protein 1, GMEB-1, DNA-binding protein p96PIF, Parvovirus initiation factor p96, PIF p96.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=May be also cytoplasmic.
Protein: RPB9B_ARATH
Sequence: MSTMKFCRECNNILYPKEDKEQSILLYACRNCDHQEAADNNCVYRNEVHHSVSEQTQILSDVASDPTLPRTKAVRCAKCQHGEAVFFQATARGEEGMTLFFVCCNPNCSHRWRE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  Component of RNA polymerases IV and V which mediate short-interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements.  Required for RNA silencing.
What are the official names of this protein?
DNA-directed RNA polymerases II, IV and V subunit 9B.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ESSC_STAAR
Sequence: MHKLIIKYNKQLKMLNLRDGKTYTISEDERADITLKSLGEVIHLEQNNQGTWQANHTSINKVLVRKGDLDDITLQLYTEADYASFAYPSIQDTMTIGSNAYDDMVIQSLMNAIIIKDFQSIQETQYVRIVHDKNTDVYINYELQEQLTNKAYIGDHIYVEGIWLEVQADGLNVLSQNTVASSLIRLTQEMPHAQADDYNTYHRSPRIIHREPTDDIKIERPPQPIQKNNTVIWRSIIPPLVMIALTVVIFLVRPIGIYILMMIGMSTVTIVFGITTYFSEKKKYNKDVEKREKDYKAYLDNKSKEINKAIKAQRFSLNYHYPTVAEIKDIVETKAPRIYEKTSHHHDFLHYKLGIANVEKSFKLDYQEEEFNQRRDELFDDAKELYEFYTDVEQAPLINDLNHGPIAYIGARHLILEELEKMLIQLSTFHSYHDLEFLFVTREDEVETLKWARWLPHMTLRGQNIRGFVYNQRTRDQILTSIYSMIKERIQAVRERSRSNEQIIFTPQLVFVITDMSLIIDHVILEYVNQDLSEYGISLIFVEDVIESLPEHVDTIIDIKSRTEGELITKEKELVQLKFTPENIDNVDKEYIARRLANLIHVEHLKNAIPDSITFLEMYNVKEVDQLDVVNRWRQNETYKTMAVPLGVRGKDDILSLNLHEKAHGPHGLVAGTTGSGKSEIIQSYILSLAINFHPHEVAFLLIDYKGGGMANLFKDLVHLVGTITNLDGDEAMRALTSIKAELRKRQRLFGEHDVNHINQYHKLFKEGVATEPMPHLFIISDEFAELKSEQPDFMKELVSTARIGRSLGIHLILATQKPSGVVDDQIWSNSKFKLALKVQDRQDSNEILKTPDAADITLPGRAYLQVGNNEIYELFQSAWSGATYDIEGDKLEVEDKTIYMINDYGQLQAINKDLSGLEDEETKENQTELEAVIDHIESITTRLEIEEVKRPWLPPLPENVYQEDLVETDFRKLWSDDAKEVELTLGLKDVPEEQYQGPMVLQLKKAGHIALIGSPGYGRTTFLHNIIFDVARHHRPDQAHMYLFDFGTNGLMPVTDIPHVADYFTVDQEDKIAKAIRKIHDIISERKRLLSQERVVNIEQYNKETGNSIPNVFLIIDNYDTVKESPFMEEYEEMMSKVTREGLALGVYIILSGSRSSAIKSAIFTNIKTRVALYLFENNELTNIIGSYKKGVKDVKGRAAINDDNFTQFQIAQPFELAEGQTYNERIKNEVAQMKEFYVGDYPKHIPMMPDKVFMEDIREAYDLEKIIHEEHKLPLGLDFEDVELVSLDLTSSSIVTAIKPTEMEKMNDVIMSSLSVYSKNQFVILVDAEDNMSQYSEDVTSYYSAPSDLSNIRLGFKQEIEARKNGEKSIEECKIVFINNIKRFNQLTGMTEDEIRVLFNEGQKVNIIIIASGLYSDTIGAFDRESKMMVRTINQALISHKISEQEFIRVKDRFGEPELKVGEMYYINNQEYQKIKLMEG
What is the function of this protein?
Component of the type VII secretion system (Ess).  Required for the secretion of substrates including EsxA and EsxB.  However, unable to support secretion of the substrate protein EsxC.
What are the official names of this protein?
Type VII secretion system protein EssC.
What is the protein family that this protein belongs to?
Belongs to the EssC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNFE_PSEAB
Sequence: MSEQDFREIARNGLWRNNPGLVQLLGLCPLLGTSNSTVNALGLGLATMLVLACSNAAVSLVRGAVSEAIRLPAFVMIIAALTTCIELLMQAWTYELYQVLGIFIPLITTNCVILGRAEAFAAKNGVLRASFDGLLMGLGFALVLLVLGGLRELLGQGTLLADMHLLFGPAAADWKIQPFPQYQGFLLAILPPGAFIMLGLLIALKNRIDESLAERAKVQAGDVPATQRQRVRVTGVIE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDUB3_HUMAN
Sequence: MAHEHGHEHGHHKMELPDYRQWKIEGTPLETIQKKLAAKGLRDPWGRNEAWRYMGGFAKSVSFSDVFFKGFKWGFAAFVVAVGAEYYLESLNKDKKHH
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3, Complex I-B12, CI-B12, NADH-ubiquinone oxidoreductase B12 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB3 subunit family.
Protein: MACB_SALTY
Sequence: MTALLELCNVSRSYPSGEEQVAVLKDISLQIHAGEMVAIVGVSGSGKSTLMNILGCLDKPTSGTYRVAGRDVSTLDPDALAQLRREHFGFIFQRYHLLSHLTAAQNVEIPAVYAGIERKKRQARARELLLRLGLSDRVDYPPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILRQLRDRGHTVIIVTHDPLIAAQAERIIEIHDGKIVHNPPAQEKKREQGVDAAVVNTAPGWRQFASSFREALSMAWLAMAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRAMGTNTIDIHPGKDFGDDNPQYRQALKYDDLVAIQKQPWVNSATPSVSKSLRLRYGNIDIAVNANGVSGDYFNVYGMSFREGNTFNAVQQQDRAQVVVLDANTRRQLFPNKANVVGEVVLAGNMPVIVIGVAEEKPSMYGNSNLLQVWLPYSTMSDRIMGQSWLNSITVRVKDGVDSDQAEQQLTRLLTLRHGKKDFFTWNMDSVLKTAEKTTYTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGISLSMFIAFMLQLFLPGWEIGFSLTALASAFLCSTFTGILFGWLPARNAARLDPVDALARE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS14Z_CAMJD
Sequence: MAKKSMIAKAARKPKFKVRAYTRCQICGRPHSVYRDFGICRVCLRKMGNEGLIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: MCSB_CHLTR
Sequence: MLPNHILTAIATIKHSLRTETPRPICTLSLSRNLSVSKFVPCLSKENKRDVLETIAKQFSAIEGEEFFVLPLKDLPIWQRECLLEHYLFPYHLGSYLEGEALIVNQAGTLLAGINLRDHLVIHGVDFVWQPEVLLQKLIDLDIRLQQSLSFAFSSDFGFLTADPLRCGTALIARAFVHVPALKYGDALSELLVPYQREFASSSLLPLSQESLGDILCLSNICSLGLSEEQILSSLRLVVSKILSAEREARNQLVKENPTEIKNRILRSVGMLTHSCCLDLQEALDATSWIQLGMSMQWIEDSEKHPLWNPLFWDLRRGHLALYNQDTANRSIEKEVIAQIRAKATKPQAERLIIRI
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: RL3_MYCMS
Sequence: MKGILGRKVEMTQVFTSAGQLVPVTVVEVLPNTVLQVKTIDSDGYVAVQLGTTDKRVNLVNKPELGHFKKANSNPKRFVKEIRNMQGYELGQVINVSDIFVSGEYVDVTGISKGKGFAGGIKRHNYARGPMAHGSGYHRGIGSMGAIINRIFKSKKMPGHMGNAKRTIQNLEIIAIDQPNNIMLIKGSIPGSKNSFVQIKQNIKGMSSKQAVELLNRNASIEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RANB3_PONAB
Sequence: MADLANEEKPAIAPPVFVFQKDKGQKRSAGSSSPEGGEDSDREDGNYRPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIRGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAARRSPAEAADEEKEPQKNESSNASGEEACEKKDPATQQAFVFGQNLRDRVKLINESMDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQVVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST
What is the function of this protein?
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein.  Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction.  In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex.  Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1.  Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner.  Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export (By similarity).
What are the official names of this protein?
Ran-binding protein 3, RanBP3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MUTS_AZOVD
Sequence: MESLSQHTPMMQQYWKLKREHPDQLMFYRMGDFYELFYEDAKKAAKLLDITLTARGQSAGKSIPMAGIPFHSVEGYLAKLVKLGESVAICEQIGDPATTKGPVERQVVRIITPGTVSDEALLDERRDNLLAAVVGDERLFGLAILDITSGRFNVQEIQGWENLLAELERLNPAELLYPDDWPAGLPLEKRRGAHRRAPWDFDFDSAYKSLCQQFATQDLKGFGCDGLGLAIGAAGCLLAYARETQRTALPHLRGLRHERLDDTVILDGASRRNLELDVNLSGGRDNTLQSVIDRCQTAMGSRLLGRWLNRPLRDRAVLEARQDTVACLLQDYRFESLQPQLKEIGDVERILARIGLRNARPRDLARLRDALAALPQLQTALSPLEAPHLQALAGNIRTYPELAELLRRAIIDNPPAVIRDGGVLKQGYDAELDELLSLSENAGQFLMDLEAREKARTGLPNLKVGYNRIHGYYIELPRVQAEQAPADYIRRQTLKGAERFITPELKAFEDKALSAKSRALAREKALYEELLEILIAQLAPLQETATALAELDVLANLAERALNLDFNRPRFVEEPCLRIRQGRHPVVEQVLDTPFVANDLELDDNTRMLIITGPNMGGKSTYMRQTALIVLLAHIGSFVPAQSCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNASERSLVLMDEVGRGTSTFDGLSLAWAAAEHLAGLRAWTLFATHYFELTVLAESQPVVANVHLSATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPGPVISRAREHLARLEATSLPHEAPLREAGKPQPPIQSDLFASLPHPLMEELARLKPDDLSPRQALELLYSWKTRL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.