PharMolix/UniProtQA huggingface dataset:
Protein: PSBA1_SYNEL
Sequence: MTTTLQRRESANLWERFCNWVTSTDNRLYVGWFGVIMIPTLLAATICFVIAFIAAPPVDIDGIREPVSGSLLYGNNIITGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLIIFHFLLGASCYMGRQWELSYRLGMRPWICVAYSAPLASAFAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHQLGVAGVFGGALFCAMHGSLVTSSLIRETTETESANYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGVWFTALGISTMAFNLNGFNFNHSVIDAKGNVINTWADIINRANLGMEVMHERNAHNFPLDLASAESAPVAMIAPSING
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 1, PSII D1 protein 1, Photosystem II Q(B) protein 1.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: YITQ_BACSU
Sequence: MNGQLIIDRYMEELNAELANMPDVERENAIDELKGHITAFVQDRIKAGLSEEELQEAVESEFSHPKELAELMMGDGGETKRRRSLLGKSWISVLLIVTIIALPLLPSDFRHLPLAVYLMVLAGYVWKRKKLVMFAGVRKNKMRSQKEIVKISRVGAVYLLFLAVVLLLSPFLNALVVLLLIAVSCAAFFLFLNIK
What are the official names of this protein?
Uncharacterized protein YitQ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: E13C_HORVU
Sequence: MARKGVDVAVALVLVALAAFPAVHSIGVCNGVLGNNLPAPSDVVTLYRSKRIDAMRIYEPESKVLTALSGTGIAVLMDVGPALPSLASSPSAAAAWVKANVSSFPGVSFRYIAVRNEVMDSAGQSTILPAMRNVQRALAAAGSPIKVSTSVRFDVFNNTSPPSNGVLADKSGFLRPILNFLARPARPLLANVYPYFAYKGNPRDIQLTFATFVPGSTTVNDNGLTYTNLFDAMVDSIYAALEKAGTPGVKVVISESGWPSDQGFGATAQNARAYNQGLINHVGNGSPKKAGALESYIFAMFNENLKDGDELEKNFGLFKPNMSPAYAITF
What is the function of this protein?
May provide a degree of protection against microbial invasion of germinated barley grain through its ability to degrade fungal cell wall polysaccharides.
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase GIII, (1->3)-beta-glucan endohydrolase GIII, (1->3)-beta-glucanase isoenzyme GIII, Beta-1,3-endoglucanase GIII.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
Protein: GAST_RAT
Sequence: MPRLCVCMLVLVLALATFSEASWKPRSQLQDASSGPRTNGALEQHQLEKLGPASHHRRQLGPQGPQHFIADLSKKQRPPMEEEEEAYGWMDFGRRSAEEEDQYN
What is the function of this protein?
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes.  It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
What are the official names of this protein?
Gastrin.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBP1C_ARATH
Sequence: MASTEPERENREDETEVNEDEDTGAQVAPIVRLEEVAVTTGEEDEDAVLDLKSKMYRFDKEGNQWKERGAGTVKLLKHKETGKVRLVMRQSKTLKICANHLISSGMSVQEHSGNEKSCLWHATDFSDGELKDELFCIRFASIENCKTFMEKFTEIAESQQVGKESTQGDEAAGLIENLSVEENISEEKAKEAEEKEPAKEDKETKKEKVEEEKKTEAST
What are the official names of this protein?
Ran-binding protein 1 homolog c.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex.
Protein: YDBL_ECOLI
Sequence: MKKTLLLCAFLVGLVSSNVMALTLDEARTQGRVGETFYGYLVALKTDAETEKLVADINAERKASYQQLAKQNNVSVDDIAKLAGQKLVARAKPGEYVQGINGKWVRKF
What are the official names of this protein?
Uncharacterized protein YdbL.
Protein: TYPH_BURMS
Sequence: MTFLPQEFIRKVRDRAPLDTADVARFVQGVTAGDVTEGQIAAFAMAVYFNELPLSARIALTLAQRDSGDVLDWRGARLNGPVVDKHSTGGVGDLTSLVIGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGYDVAPSVDMLRRVVRDAGLAIVGQTAQLAPADKRIYAVRDVTATVESISLITASILSKKLAAGVGALAMDVKVGSGAFMPSAEQSAELARSIVDVGNGAGMRTAATLTDMNQALAPCAGNAIEVRCAIDFLTGAARPARLEAVSFALAAQMLTMGGLAADAHDARRRLRAVLESGAAAERFARMVAALGGPADLVERPERHLPRAAAAAPVAAARAGWIERIDARALGLAVVGLGGGRAKIGDTLDYSVGLSALAELGERVEAGQPLATVHARDADSAAQATDAVRRAYRIGAEPPAQTRVVHAVIE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: MUB3_ORYSJ
Sequence: MAGGKEPIEVKFRLFDGTDIGPSKYDPSTTVSALKEFILARWPQDKEITPKTVNDLKLINAGRILENNRTLAESRVPVGEVPGGVITMHVVVRPPQPDKNSEKQLANSPKQNRCGCTIL
What is the function of this protein?
May serve as docking site to facilitate the association of other proteins to the plasma membrane.
What are the official names of this protein?
Membrane-anchored ubiquitin-fold protein 3, Membrane-anchored ub-fold protein 3, OsMUB3.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: KGX13_CENGR
Sequence: DRDSCVDKSRCAKYGHYQECTDCCKKYGHNGGTCMFFKCKCA
What is the function of this protein?
Blocks Kv11/ERG potassium channels.
What are the official names of this protein?
Potassium channel toxin gamma-KTx 1.3, CgErgTx1, CgErg1, Ergtoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_AZOPC
Sequence: MADLKAFAEQLVNLTIKEVSELTEILKTEYGIELATSSSVATGVSTSVVEVREEKTSFDLILKGVGTNKLAIVKLVKELTGLGLKEAKGIVDNAPAPLKEGITRNEAETLKKSLEEAGAEIDIR
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: HSLU_ECOSM
Sequence: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQTITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_ECOL6
Sequence: MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMSEWQLSDNAAYMHYCPNETIDGIAIDETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNDSMFNTPPTFAWYLSGLVFKWLKANGGVAAMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMVEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB3_MAGSA
Sequence: MTEQPAQPKMTARSLAVHYGGKPALKGVDLDIVAGEVNALIGPSGCGKSTFLRCLNRMNDTIPAAKVSGQATLDGEDIYGPAGMDPVLLRARVGMVFQRPNPFPKSIYDNVAFGPRLHGLVAEGDEMDVLVRTSLERAGLWKEVKDVLGNLGTSLSGGQQQRLCIARAIAVSPEVILMDEPCSALDPIATARIEELIDELRDVFTIVMVTHSMQQAARVSQTTAFFHLGEIVEVGATEQIFTAPANSLTQGYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 3, ABC phosphate transporter 3, Phosphate-transporting ATPase 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GPPA_ALIFM
Sequence: MKSSTIPPMYAAIDLGSNSFHMLVVRHINGSVQTMAKIKRKVRLAAGLNENNTLSHEAMQRGWDCLSLFAERLQDIPVENIRIVGTATLRVASNVDIFLEKANQILGHNINVIEGEEEARMIYQGVAHTSGGNGRRLVVDIGGASTELIIGEGFEAQALTSLKMGCVTWLEGYFKDRALTQKNFDSAIAGAKETLAPILQQYTDLGWQTCVGASGTVQALQEIMLAQGMDEVITLAKLKRLQKQAMQYEHLEELDIDGLTLERALVFPSGLSILIAIFELLNIDSMTLAGGALREGLCYGMIDELQHDEVCQRTIKSTQQRYQLDVEYAQQVTDLSIQLVQQCGNDWLTEPQALPLLTAATQLHEIGMCIDYKKGGEHSAYLINALDLPGFTRAQKHLLGELLRRYREYFSAMPTQHAVSDISAQRMLRILRLAIILTHRRDVNLAPAVTLSEKNDVLSLSIDGTWLAANPLTRSELEIEADKQTNIGWDLVIDARD
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: CSK2B_RAT
Sequence: MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
What is the function of this protein?
Regulatory subunit of casein kinase II/CK2.  As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (PubMed:16818610).  Participates in Wnt signaling (By similarity).
What are the official names of this protein?
Casein kinase II subunit beta, CK II beta, Phosvitin.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: RS8_MYCPN
Sequence: MITTTKPIKAHFDPVADLLTKINNARKAKLMTVTTIASKLKIAILEILVKEGYLANFQVLENKSKTKRIVTFNLKYTQRRIPSINGVKQISKPGLRIYRPFEKLPLVLNGLGIAIISTSDGVMTDKVARLKKIGGEILAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NDRG4_XENTR
Sequence: MKLLGHKIELWAGLLLPDVSISGMSELRFPEEKPLLRGQDTEMESADTFLSAADTDWKEHDIETPYGMLHVVIRGTPKGNRPAILTYHDVGLNHKLCFNTFFNYEDMQEITKHFVVCHVDAPGQQVGASQFPQGYQYPTMEQLAAMLPSVMQHFGFQSIIGIGVGAGAYVLAKFALIFPELVEGMVLVNIDPNGKGWIDWAASKLSGLTSSLPETVLSHLFSQEELMNNTELVQNYRQQISSCVNQSNLQLFWNMYNSRRDLEMSRPGTVPNAKTLRAPVMLVVGDNAPAEDCVVECNSKLDPTNTTFLKMADSGGLPQVTQPGKLTEAFKYFLQGMGYIASLKDRRQSASAGAVPSASMTRLARSRTASLTSASSVDGARPRPCTQSESSDGIGQINHTMEVSC
What is the function of this protein?
Contributes to the maintenance of intracerebral BDNF levels within the normal range.  May enhance growth factor-induced ERK1 and ERK2 phosphorylation.  May attenuate growth factor-promoted ELK1 phosphorylation in a microtubule-dependent manner (By similarity).
What are the official names of this protein?
Protein NDRG4.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PYRDB_CLOD6
Sequence: MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISSKGLTLNKKPGNNGMRVHETSSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGGGTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLPLVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPAIKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFINPRIGIEIIDGINEFMDREGIKSLDEIRGII
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H4_MYTTR
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SHUT_GAHVM
Sequence: MGVYGCMNFAYANGLVRSHISGFISGGDMTPIAVDLWNVMYGLLEKLYPGKIDGVDDSIITLRCLYCLLRLLHQRSYYPVFVADRGFYGNGKTLYGAKAIAATCIATRGGSGRLHARLFDECGSTDVGEARCKRKHPGKKVCRWSERFETPKILYQLCMSIIRYMGYPYVDAGTMEADDICANLFHTKTVAYVLSSDTDLILMGCDIIIDLTRIFPPTIYCRDVLAALQMDYFTFLLNFVRCHTDLHREPTLKSMQEIINLSSAKRCLHDTDCATDDDVPRCIRPLYEEQDRRTGENSYHSEGFDLHIRKDQSKTSCWDNDVSNYTDTNLIRGVQKALKSLRPPRTRCEILEYKFIKHVIATIIPERRTSRVSILKRFPIMQEGRDETAVEDLIFCNIFDVDEASTIVSQFIKRIPEVRPLNHILLKYWGNDALKTTRSND
What is the function of this protein?
Minor structural protein that acts as an endoribonuclease during lytic infection.  Degrades host mRNAs in the cytoplasm by cutting them at preferred sites, including some in regions of translation initiation (By similarity).
What are the official names of this protein?
Virion host shutoff protein, Vhs.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae VHS protein family.
What are the subcellular locations of this protein?
Virion.
Protein: UBC5A_ORYSJ
Sequence: MASKRIQKELKDLQKDPPTSCSAGPVGEDMFHWQATIMGPSDSPYAGGVFLVTIHFPPDYPFKPPKVAFRTKVFHPNINSNGSICLDILKDQWSPALTISKVLLSICSLLTDPNPDDPLVPEIAHMYKTDRHKYENTARTWTQRYAM
What is the function of this protein?
E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 5A, E2 ubiquitin-conjugating enzyme 5A, Ubiquitin carrier protein 5a, OsUBC5a, Ubiquitin-protein ligase 5A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RL10_BACCR
Sequence: MSKVMETKQQVVTEIADKLRASKSTIVVDYRGLTVSEATELRKQLREAGVEFKVYKNSLTRRAAESAEMAELNEFLTGPNAIAFSNEDVVAPAKVLNDFAKDHEALEIKAGVIEGKLVTLDEVKAIATLPSREGLLSMLLSVLQAPIRNLALATKAVADQKEEQGA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: EFTS_GUITH
Sequence: MTIEISAKTVKELRERTSAGMMDCKKALQECNGDFEKAVETLKQKGLVSAAKKAARVATEGIIESYIHMGGKLGILVELNCETDFVARRPEFQELAKNIAMQIAACPNVDYIKTSDIPNEIIQKEKETEMNKNDLDNKPTEIKEKIVEGRIQKRLKELSLMDQSYIRDSSILIEELIKENIAKLGENIQIRRFERFTLGEGLEKREDNFNEEVNKMLTK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, chloroplastic, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LYSC_PAPAN
Sequence: MKAVIILGLVLLSVTVQGKIFERCELARTLKRLGLDGYRGISLANWVCLAKWESDYNTQATNYNPGDQSTDYGIFQINSHYWCNNGKTPGAVNACHISCNALLQDNIADAVTCAKRVVSDPQGIRAWVAWRNHCQNRDVSQYVQGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPF_PASMU
Sequence: MIRIGHGFDVHAFGGEGPIIIGGVAIPYEKGLLAHSDGDVALHALTDALLGAVALGDIGKLFPDTDMQYKGADSRGLLREAYTQVQAKGYKVGNVDVTIIAQAPKMRPHIDAMRAAIAEDLACDIEQVNVKATTSERLGFTGRGEGIACEAVALVVKS
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: S22AL_MOUSE
Sequence: MLDYDEVTAFLGEWGTFQRLIFFLLSASIIPNGFTGLSAVFLTAIPEHRCRIPDTVNLSSAWRNHSIPMETKDGPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLLVQLVPSDLHYLSTTLVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILTAIITLFFPESSGVSLPETIDEMQKVKKLKQRQSLSKKGSPKESKGNVSRTSRTSEPKGF
What is the function of this protein?
Sodium-ion independent, medium affinity carnitine transporter.  Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium.  Relative uptake activity ratio of carnitine to TEA is 746.
What are the official names of this protein?
Solute carrier family 22 member 21, Organic cation/carnitine transporter 3, Solute carrier family 22 member 9.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Protein: MPPB_CAEEL
Sequence: MYRRLASGLYQTSQRRIAQVQPKSVFVPETIVTTLPNGFRVATENTGGSTATIGVFIDAGSRYENEKNNGTAHFLEHMAFKGTPRRTRMGLELEVENIGAHLNAYTSRESTTYYAKCFTEKLDQSVDILSDILLNSSLATKDIEAERGVIIREMEEVAQNFQEVVFDILHADVFKGNPLSYTILGPIELIQTINKNDLQGYINTHYRSGRMVLAAAGGVNHDAIVKMAEKYFGELKHGDSSTEFVPATYSPCEVRGDIPDLPMLYGAMVVEGVSWTHEDNLALMVANTLMGEYDRMRGFGVNAPTRLAEKLSQDAGIEVFQSFNTCYKETGLVGTYFVAAPESIDNLIDSVLQQWVWLANNIDEAAVDRAKRSLHTNLLLMLDGSTPVCEDIGRQLLCYGRRIPTPELHARIESITVQQLRDVCRRVFLEGQVSAAVVGKTQYWPVNEEIHGRLIRMQ
What is the function of this protein?
Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable).  Preferentially, cleaves after an arginine at position P2 (Probable).
What are the official names of this protein?
Mitochondrial-processing peptidase subunit beta, Beta-MPP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SSRP_CHLL3
Sequence: MAKKQQTRSYTEAIQNRKARYEYQILETIVAGIELLGSEVKSVRLGKASLNESFATIHHDEVWLENMQITPYEFNHLDALEPKRSRKLLLHKEEIRRLQSKINEKGLTLIPLKAFFDKNGRLKVELALAKGKKLYDKRETIKGRENERHLQQLRKQY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL28_XENLA
Sequence: ATSYEKITINKNSRSTLSSVRHIIRKNNYRKDL
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL28 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB1_RHOP5
Sequence: MSYELQRPGEEMPIEEQMARTSLFTRLEDLVAWSRKNSLWPFNFGLSCCYVEQVTALTPVFDQARFGAEVIRASPRQADLLVVSGTVFHKMAAPLLRLYEQMRAPRWVISMGACANSGGMYDVYSVVQGVDSFLPVDVYIPGCPPRPEAVLDALILLQQQVGAQRRPLGVTVGNAAGLGFEAPRRRDQRRDERMAQTLLDPPEKL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.