PharMolix/UniProtQA huggingface dataset:
Protein: KCY_BART1
Sequence: MKPFVIAIDGPAASGKGTLARKIAAHYHLHHLDTGLTYRGVAYALLQHNLALDDEKNAITYAKELDFNTLNLAFLSSHELGEAASKIALNPTIRKILVEKQRNFAKTLPGSVLDGRDIGTIVCPDADIKFYILANVQTRAKRRYQEILKKGGQANYHEILNDLEQRDSRDITRKESPLKPAENAHLLDTSELSIEATFAIACSFIDPIIKMHIIG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_THEPX
Sequence: MARVDWTKLDLKERVVSINRVSKVVKGGKNFRFSVTVVVGDAERGYVGVGRGKAAEIPDAIRKAIEDAKKHLIKVPIVGTTIPHEVIGEFGAGKVLLKPAREGTGVIAGGPVRAVLESAGIKDVLTKSLGSSNATNMVYATIEGLKRLRTAEDVAKLRGIPVSQLFE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MT1_TETPY
Sequence: MDKVNNNCCCGENAKPCCTDPNSGCCCVSETNNCCKSDKKECCTGTGEGCKCTGCKCCEPAKSGCCCGDKAKACCTDPNSGCCCSSKTNKCCDSTNKTECKTCECCK
What is the function of this protein?
The metallothioneins are involved in the cellular sequestration of toxic metal ions.  Binds 12 cadmium ions per molecule.
What are the official names of this protein?
Metallothionein-1, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 7 family.
Protein: OSTCA_XENLA
Sequence: MESLYRVPFTVLECPNLKLKKPSWLHMPSAMTVYAMVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG
What is the function of this protein?
Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Oligosaccharyltransferase complex subunit ostc-A.
What is the protein family that this protein belongs to?
Belongs to the OSTC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RSMA_CLOBK
Sequence: MNTKEIVNKYEFKFNKNLGQNFLIDESVLEDIIEGAEISKEDTVIEIGPGVGTLTKELLERAKEVYSIELDGDLIPILQEELKEYNNFTLIHKDALKINFNELMENKDSIKLVANLPYYVTTPIISRLLTEKCDFKSLTIMIQKEVAERINAEPNCKEYGSLTVLVQYYCNTKIIRKVSPNSFIPKPKVDSIVIKLDRLSEPRVRVKSQKLFFNVVRSSFNMRRKTLWNSLKSLNIDKESMENAFERAGIDPKRRGETLSIEEFGKLSDCIYDIL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_HYPNA
Sequence: MRHQIAHRKLNRTASHRKAMFANMAASLIEHEQIVTTLPKAKEMAPLMDKLVSLAKKGDLAARRAALSQVRNETAVRKLFDVFGDRYKDRNGGYTRVVKAGFRPGDNAPIAVLELVDRDESAKGAADKARHAAELEAAEG
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MATK_SCHTR
Sequence: MEEFQRYIELDRSWQHNFVYPLIFQEYIYGFAYDHGLNKYILLENAGDKKYSLLIVKRLINRMYQQTHWILFANHSNQNDFFGHKHKKNLYYQIISEGFAVIVEIPFSPLLISSLEAKEKKIVKSHNLRSIHSIFPFFEDKFLHLNYVLEILIPYPIHLEILVQTLRYWVKDASSLHLLRFFLYEYRNWNSLITPQKSISIFSKRNQRLFLFLYNFHVCEYESIFVFLCNQSSHLRSTSFGALLERNYFYGKLEYLVKVFTFTKDFCVILWLLKDPFLHYVRYRGKSILASKGTPLLMHKWKYFLFNFWQCHFSLWSPPRRIYINRLSKHSLDFMGFFSSVRLNSSVVRSQMVENSFLIDNPIKKFDTIVRIIPLVGSLAKAKFCNVLGHPISKSVWTDLLDSDIMDRFGRICRNLSHYYSGSSRKKSLYRIKYILRLSCARTLARKHKSTVRAFLKRLGSEFLEEFFTEEEKVLSLILPRDSSISRGLYRGPFWYLDIICIHDLANDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ICI2_CANLI
Sequence: NDVDVVMDASSKPIFPGGEYYIMPAIWGPPGGGVRLAKTRNSDCPVTVLQDYGEVIFGQPVKFTLPGRGSGLIITNTPVEEFIKKPECASSSKWSVFVDDEIEKACVGIGGHEDHPGEQVFSGTFTIQKSRTPYNSYKLVFCESDSSTCSDIGRYDNNEGGRRLILTHHNPFQVVFMDASTFDGTIRSDG
What is the function of this protein?
Inhibits subtilisin-type microbial serine proteases incuding proteinase K, subtilisin BPN', subtilisin Carlsberg and subtilisin E in a non-stoichiometric manner.  Weakly inhibits A. oryzae protease and some metalloproteases including pronase E.  Does not inhibit trypsin, chymotrypsin, S. griseus alkaline protease or A. lyticus lysyl endopeptidase.  CLSI-II has a wider inhibitory specificity than CLSI-III.
What are the official names of this protein?
Subtilisin inhibitor CLSI-II.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARAG_RHIL3
Sequence: MMAFLEFSNISKGYPGVQALANVSFTVEKGAVHGLMGENGAGKSTLIRVLSGDQAADAGNILIDGEEQKYGSVRDAFHAGVIVIHQELQLVPELTVAENLWLGRFPAKGGVIHSKTLIETVRSKLEEIGIDIDPSAKVASLSIGARQMVEIAKAVMLDARVIALDEPTSSLSSRESEILFSLIDRLKAKGTVILYVSHRLDEIFRLCDSLTVLRDGKLAAHHPQIAETTREQIISEMVGREISNVWGWRERPLGGIRLEVNGLSGPRLRHPISFSVRQGEILGFFGLIGAGRSEMARLLYGADARHQGQVTIDGVAVSPNNPKAAINAGMVLCPEDRKFDGIVQGRSIEENIAISSRRHFSPFGILSPRQEAALADRFIAKLRVRTPSRKQDIINLSGGNQQKVILGRWLSEQGIKVLVIDEPTRGIDVGAKSEIYEILYELAAGGMAIVVISSELPEVMGISDRIMVMCQGRVAANVARPDFDERSILTAALPDKNAAGTL
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ZN841_HUMAN
Sequence: MLEGHESYDTENFYFREIRKNLQEVDFQWKDGEINYKEGPMTHKNNLTGQRVRHSQGDVENKHMENQLILRFQSGLGELQKFQTAEKIYGCNQIERTVNNCFLASPLQRIFPGVQTNISRKYGNDFLQLSLPTQDEKTHIREKPYIGNECGKAFRVSSSLINHQMIHTTEKPYRCNESGKAFHRGSLLTVHQIVHTRGKPYQCDVCGRIFRQNSDLVNHRRSHTGDKPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNRCGKCFSQSSSLATHQTVHTGDKPYKCNECGKTFKRNSSLTAHHIIHAGKKPYTCDVCGKVFYQNSQLVRHQIIHTGETPYKCNECGKVFFQRSRLAGHRRIHTGEKPYKCNECGKVFSQHSHLAVHQRVHTGEKPYKCNECGKAFNWGSLLTVHQRIHTGEKPYKCNVCGKVFNYGGYLSVHMRCHTGEKPLHCNKCGMVFTYYSCLARHQRMHTGEKPYKCNVCGKVFIDSGNLSIHRRSHTGEKPFQCNECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAYTQRSSLTKHLVIHTGENPYHCNEFGEAFIQSSKLARYHRNPTGEKPHKCSECGRTFSHKTSLVYHQRRHTGEMPYKCIECGKVFNSTTTLARHRRIHTGEKPYKCNECGKVFRYRSGLARHWSIHTGEKPYKCNECGKAFRVRSILLNHQMMHTGEKPYKCNECGKAFIERSNLVYHQRNHTGEKPYKCMECGKAFGRRSCLTKHQRIHSSEKPYKCNECGKSYISRSGLTKHQIKHAGENLTTKLNVERPLDVVLTSGIPK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 841.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGA2_NITOC
Sequence: MYKILFATSEAHPLIKTGGLGDVAGILPIELARLGLEAGIILPAYPACKTHLKNLKEVARLRLPAALEPVRILKGQLLEGPNPVWLVDSPAHFDRPGNPYLNEQGQDWPDNAARFTTFCRAVATLANSPEFDWQPDLIHCNDWQTGLIPPFLAPLRSRPATLFTIHNLAYQGVFSRQQFDALELPSAWWSPAALEFYNQISFIKGGLVFADWLTTVSPTYAKEILTPEFGCGLDGVLRGRSKRLTGILNGADYQRWDPRHDPFIEKRYDQTCWSHKASNKLALQRRYGLPEDDTLPVLGFVGRLVEQKGIDLILGALPKLLAEKIQVVFLGEGEERHQNALQQLASRYPNQIGVSISYDERLAHGVQAGADIFLMPSRFEPCGLTQLYALRYGTVPIARRTGGLSDTIVDATEKNLRQELATGFTFTESSPSALLTAIQRALACYAQSRQWRRLALTGMAQNFSWQTSAKAYFDLYQQLVSQEFSCKNNVL
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase 2, Starch [bacterial glycogen] synthase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: ATPI_EUCGG
Sequence: MNVLSCSTNTLKGLYDISGVEVGQHFYWQIGGFQVHGQVLITSWVVIAILLGSASIAVRNPQTIPNDSQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIELPHGELAAPTNDINTTVALALLTSVAYFYAGLTKKGLSYFSKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: APAH_KLEAE
Sequence: EFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDTVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: Y139_CHLPN
Sequence: MKIPYARLEKGSLLVASPDINQGVFARSVILLCEHSLNGSFGLILNKTLGFEISDDIFTFEKVSNHNIRFCMGGPLQANQMMLLHSCSEIPEQTLEICPSVYLGGDLPFLQEIASSESGPEINLCFGYSGWQAGQLEKEFLSNDWFLAPGNKDYVFYSEPEDLWALVLKDLGGKYASLSTVPDNLLLN
What are the official names of this protein?
UPF0301 protein CPn_0139/CP_0633/CPj0139/CpB0140.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: UPPP_BORBU
Sequence: MTNILSAIILGIIQGITEFLPISSSGHLLLFRHFINLKLSIIFDIYLHLATVLVIIIYYRKRILELFLTFIRFSLRKTVKSDLTNLKLILLILIITIVTGVVGTFISKYESMFTLSFVLINFIITGILILMLEFNFLKVDFKGNILLAGIFMGLMQGLGALPGISRSGITIFSASVIGFNRKSAFEISFLSLIPIVFGAILLKHKEFYDIFMVLNFFEINLGALVAFVVGIFSINFFFKMLNNKKLYYFSIYLFALSIIVCYFVRI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU2M_BONBI
Sequence: MNPLIFTTIVLTIIMGTMIVMTSSHWLTVWIGFEMNMLAVIPILMKNYNPRSMEASTKYFLTQATASMLLMLAIIINLLYSGQWSITKPLNQTASIIMTLAMAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQIFPTINLNLMLLMSVLSVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAIMAYNPTMTLLNLVIYILLTTTTFMMFMLNSSTTTLSLSHTWNKAPLLTMTILTIMLSMGGLPPLSGFLPKWMIIQEMVKNDNIITPTIMAVTALLNLYFYMRLTYSTSLTMFPSTNNMKMKWQLNNTKSTAHVSPLIILSTLALPLSPILMLLE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PTH_SINFN
Sequence: MLIIAGLGNPGSKYAGNRHNIGFMAVDAIWQRQGFSSWSKKFKAEIAEGEIAGERVLLIKPQTFMNLSGEAVGEAMRFYKLAPKDIVVIYDELDLIAGKARIKIGGGHGGHNGIKSIDAHCGKEYRRLRLGIGHPGVKDLVHAHVLGDFAKADQAWLSSLLDTIADNAGMLVKGEDSQLMNKIALATGGKPDAEEPQAPKKQVGQSHIHKARNAAQPKKLPATGPMADMLKKMFGSKGD
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1390_ACTSZ
Sequence: MLCAIYKSKKKDGMYLYIEKRDDFSVLPDSLREAFGIPVFVMLFNLVGKKTLINTDNREVMEQIKQNGFYLQMPKKDDWLFTIEKSCDL
What are the official names of this protein?
YcgL domain-containing protein Asuc_1390.
Protein: PSBT_BOWSE
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPDRGSK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GATA_MYCTA
Sequence: MTDIIRSDAATLAAKIAIKEVSSAEITRACLDQIEATDETYHAFLHVAADEALAAAAAIDKQVAAGEPLPSALAGVPLALKDVFTTSDMPTTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAYGPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDSTSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAAVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRVGDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKVRTLIARDLDAAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCTLPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPLLSAI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: LIMB_DICDI
Sequence: MANKNVLSEMDDLMAELGLVETTATPTSDQIKQPQQETAPTYLTYKDPNVSTGPGGDFRNLNDNNGGISRGPGLMSTGPGLVSTGPGLMSTGPGLMSKGPGLPNNSINNNISNNNGGGISSGPGLSFGVSSGVSSGVSSGVSSGVSSGVTLVAQNHLARQPSPPLNSQQQQQQQLPTYLDGVGTLQPISLAATTPDGRVVKANGPICGACGDMIIGVCTNALGRSYHPEHFVCTYCKLPFSGSFIEHEEKLYCENDYLELFSPRCFACIKPIEDTCINALGNRYHPECFSCSGCGDKLRGKPYKEEDGEVYCNTCKIARQKRLAAKSEICSKCKLPITGEYIILQGQPVHSEHYRCEECGCEFNVGKTCHEYEGRLYCYEDYQKQILNICGACSKPIVGRSITALGKVWHPEHFTCTTCQVPFAGSAFREHAGKPYCESHYHQFFGRQCFKCSKPVVDTGVEVFGKIYHREHFTCTGCECVLGKEIMEWDGKPLCFKCFDALPKEVRKRIKEKKAGDKKAEAYREKLAKKEAKELKKERERAAKEKEKESKAK
What is the function of this protein?
Regulates and controls rearrangements of the actin cytoskeleton.  Required for tip formation, morphogenesis, cell adhesion and motility, chemotaxis and aggregates formation.  May function downstream of paxB.
What are the official names of this protein?
LIM domain-containing protein B, Paxillin-A.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Protein: YABA_STRR6
Sequence: MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLENSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELLYRE
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: ARNT2_HUMAN
Sequence: MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMTIPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASAAGTQQIYSQGSPFPSGHSGKAFSSSVVHVPGVNDIQSSSSTGQNMSQISRQLNQSQVAWTGSRPPFPGQQIPSQSSKTQSSPFGIGTSHTYPADPSSYSPLSSPATSSPSGNAYSSLANRTPGFAESGQSSGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE
What is the function of this protein?
Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function (PubMed:24022475).  Specifically recognizes the xenobiotic response element (XRE).
What are the official names of this protein?
Aryl hydrocarbon receptor nuclear translocator 2, ARNT protein 2, Class E basic helix-loop-helix protein 1, bHLHe1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPN1_CANGA
Sequence: MSTDKKKEEVPKPETEDLTVKDETKNKDKKKANEEEELSEEDQKLKGDLEMLVQTLLEDDSKLYETTLTQLKEFIKNSTSSMTAVPKPLKFLRPFYPDLCKAYDKWSDKDQKSSLADMLSVLAMTYSDTHQHDSLRFRLLSDTSNIASWGHEYVRHLALEIGEVYNEQVEKEAEDNSTSTESSPQPPHMNFEFSKDVILQLSLEIVPYFMKHNGEEDAVDLLLEIEAIEKLPQFVDENTYKRVCQYMIACVQLLPPPEDISFLQTAYSIYLSELQLPEALSLAIRLGNEDMIRSVFDATSDPIVHQQLAYILAAQRVPFEHPELQEIIGNTKLSEHFLYLAKELNLLTPKIPEDIYKSHLDSSKSVFSSAGLDSAQQNLAASFVNAFLNLGYCNDKMITDNDNWVYKTKGDGMTSAVASIGSIYQWNIDGLQQLDKYLYVDEPEVKAGGLLGIGIASAGVHHDVEPALLLLQEYINHSDTKISTAAILGIGIAFAGSKNDEVLGLLLPVVSNTENSLELAAIAALALSHVFVGTCNGDITTAVMDNFLERTPLELKSEWARFLALSLGLLYLGQGEHVDDVLETINAIEHPMTSAIEVLISSCAYTATGDVLLVQDLLHRLTPKAVKSSDEDEDEDNEELSQEDMNGISAFLGKKENEIAEEPQGNEGADNEMEVDSHQDETTTGENNVKKEENEEEKTEKSEKTENDEEEEDEEESKDEGANDELAYAVIGIALITMGEEIGKEMSLRHFGHLMHYGNEHIRRMVPLAMGLVSVADPQMKVFDTLTRFSHDPDLDVSMNSIFAMGLCGVGTNNARLAQLLRQLASYYSREQDALFITRLAQGLVHLGKGTMTMDIFNDAHVLNKVTLASLLTVLVGLISPSFILKHHQLFYMLNSGVRPKFIITLNEEGEQIKVNVRIGQAVETVGQAGKPKTITGWITQSTPVLLGHGERAELENDEYISYTNNIEGVVILKKNPNFQEEE
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome regulatory subunit RPN1.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S2 family.
Protein: RLMN_CHRVO
Sequence: MKTNLLDFNLDQLTQHFAEMGEKPFRAKQVMRWMHQMAEDDFDAMTDLAKSLRAKLHERAEVRVPSLMTGQASSDGTRKWLLDVGTGNGVETVFIPEDDRGTLCVSSQVGCALECTFCSTGRQGFNRNLSTAEIIGQLWWANKAMGVTPKNERVVSNVVMMGMGEPLANFDNVVSAMQIMLDDHGYGLSRRRVTLSTSGLVPQMDRLREECPVALAVSLHAPNDAIRDVIVPINKKYPLSELMAACRRYLEKAPRDFITFEYVMLDGVNDRPEHARQLLELVRDVPCKFNLIPFNPFPNSGYDRSSNNAIRIFREILQEQGYVVTVRKTRGDDIDAACGQLAGQVQDKTRRQAKWTQIIEDRKS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_LEGPH
Sequence: MNNVSMRELLEAGAHFGHRTRFWNPKMSEYIFGSRNKIHIINLEKTLPMLSDVTNYVSRLAANKAKILFVGTKRAAQDSIREHAKRCGMPYVDHRWLGGMLTNYKTVRQSIFRLKELKEMKEKGLFNDMIKKEALMLTRELEKLERSLGGIENMGGLPDALFVVDVGFEHIAVEEARRLRIPVIGVVDTNNSPDNIDYVIPGNDDSMRAVDIYVRCVADAILDGKNSNTVGRVSSDSEFVEVTSNSNEEEKSGE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RHAM_CLOB8
Sequence: MIQKAFKMKLFEGKEEEYKKRHNEIWPDLVKELKSHGTSKYLIFYDKDTNILFSYIEMENEELWDEIAETDACKKWWAFMKDIMETNPDNSPISVELSNVFNLK
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_GEOSW
Sequence: MLTIAMPKGRIFGEALELLRKAGYTLPPEFAESRKLMIEVPEENMRFILAKPMDVVTYVEHGVADLGIAGKDVMMEEERDVYELLDLKISKCHLAVAGLPGVRMNQIAPRVATKYPNIASSYFREQGEQVEIIRLNGSIELAPLIGLADRIVDIVSTGRTLKENGLVELEKIADVTSRLIVNPVSYRMKDEAVDELVHRLSEVIPQ
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRB_CHLMU
Sequence: MDAQEKKYDASAITVLEGLQAVRERPGMYIGDTGVTGLHHLVYEVVDNSIDEAMAGFCTEVVVRILEDGGISVSDNGRGIPVQIHEKESAKQGREISALEVVLTVLHAGGKFDKDSYKVSGGLHGVGVSCVNALSEKFIANVFKDGQAYSMEFSKGAPLTALQVLGSTDKRGTEILFYPDPTVFSTCVFDRAILMKRLRELAFLNRGITIIFEDDRDAGFDKVTFFYEGGIQSFVSYLNQNKESLFPTPIYIQGSKRGDDGDIEFEAALQWNSGYSELIYSYANNIPTRQGGTHLTGFSTALTRAVNSYIKSHNLAKSDKLSLTGEDIREGLVAIVSVKVPNPQFEGQTKQKLGNSDVGSVAQQISGEVLTTFFEENPQIAKTIVDKVFVAAQAREAAKRARELTIRKSALDSARLPGKLVDCLEKDPEKCEMYIVEGDSAGGSAKQGRDRRFQAILPIRGKILNVEKARLQKIFQNQEIGSIIAALGCGIGTDNFNLSKLRYKRVIIMTDADVDGSHIRTLLLTFFYRHMSALIENGCVYIAQPPLYRVSKKKDFRYILSEKEMDGYLLNLGTRESRVVFDDTARELEGTALESFVNLILEVESFIIALEKRAIPFSEFLDMFRDGAYPLYYYPPESGKQGGNYLYSNEEKEAAVAANEEAAARIIELYKASAFEEIQHNLNEYGYDIRHYLHPKGTGITVSTEDSKTPNYTCYTLKEVIDYLKGLGRKGIEIQRYKGLGEMNADQLWDTTMNPEQRTLVRVSLKDAVEADHIFTMLMGEEVPPRREFIESHALSIRMSNLDI
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.