PharMolix/UniProtQA huggingface dataset:
Protein: ISPG_PROMA
Sequence: MTIENTQNINIDTLSRRYSTQIQRRKTRSVMVGNIGIGSDYPVAVQSMINEDTLDIEASTSAIRRLHEIGCEIVRLTVPSLSHAKAVGEIKRRLEQNYLPVPLVADVHHNGMKIALEVAKHVDKVRINPGLFVFSNPDPSRTEFSNSEISAIKEKIINNFEPIVNTLKAQNKALRIGVNHGSLAERMLFQYGDTPLGMVESAMEFVRICDSLDFHNIVISMKASRPPVMLAAYRLMADAMDKEGFNYPLHLGVTEAGDGDYGRIKSTVGIGTLLTEGLGDTIRVSLTEAPEKEIPVAYSILQTVGLRKTMVEYISCPSCGRTLFNLEEVVAKVRDATSHLTGLDIAVMGCIVNGPGEMADADYGYVGKGKGIIALYRGREEIRKVPEDEGVSALVELIKSDGKWIDP
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: ZN548_HUMAN
Sequence: MNLTEGRVVFEDVAIYFSQEEWGHLDEAQRLLYRDVMLENLALLSSLGSWHGAEDEEAPSQQGFSVGVSEVTASKPCLSSQKVHPSETCGPPLKDILCLVEHNGIHPEQHIYICEAELFQHPKQQIGENLSRGDDWIPSFGKNHRVHMAEEIFTCMEGWKDLPATSCLLQHQGPQSEWKPYRDTEDREAFQTGQNDYKCSECGKTFTCSYSFVEHQKIHTGERSYECNKCGKFFKYSANFMKHQTVHTSERTYECRECGKSFMYNYRLMRHKRVHTGERPYECNTCGKFFRYSSTFVRHQRVHTGERPYECRECGKFFMDSSTLIKHQRVHTGERPYKCNDCGKFFRYISTLIRHQRIHTGERPYECSVCGELFRYNSSLVKHWRNHTGERPYKCSECGKSFRYHCRLIRHQRVHTGERPYECSECGKFFRYNSNLIKHWRNHTGERPYECRECGKAFSHKHILVEHQKIHSGERPYECSECQKAFIRKSHLVHHQKIHSEERLVCSMNVGNSLAKTPTSLNIRDFTMEKVYH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 548.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPIS_STRP3
Sequence: MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAPAVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDYFHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQVASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPENVKDYMACPDVDGALVGGASLEADSFLALLDFLN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO17_ADEG1
Sequence: MPLYLCFGAAAPVSILWREELFWGFVAAVKRRWHTVYARTNVDIQYPMAYCVGIQSLSPCKCHVTVVVCLTFLDLRMSAINEATKIMRAFFKTFFYHHGKVPRGRWFKLYRNDWCKDPNLTVGNYIVASGALPLMLGWARSTGLRFSTFTYSDEALWSHRRRDRRLARRREKLENKVSG
What are the official names of this protein?
Uncharacterized protein ORF17.
Protein: Y3118_MYCTU
Sequence: MCSGPKQGLTLPASVDLEKETVITGRVVDGDGQAVGGAFVRLLDSSDEFTAEVVASATGDFRFFAAPGSWTLRALSAAGNGDAVVQPSGAGIHEVDVKIT
What are the official names of this protein?
Uncharacterized protein Rv3118.
Protein: DSBC_ECO57
Sequence: MKKGFMLFTLLAAFSGFAQADDAAIQQTLAKMGIKSSDIQPAPVAGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALEKEMIVYKAPQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLDSDAEKEMKAIWCAKDKNKAFDDVMAGKSVAPASCDVDIADHYALGVQLGVSGTPAVVLSNGTLVPGYQPPKEMKEFLDEHQKMTSGK
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by transferring its disulfide bond to other proteins and is reduced in the process.  DsbC is reoxidized by a yet uncharacterized protein.  Also acts as a disulfide isomerase (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbC.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbC subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PYRB_PSECP
Sequence: MKHLLSTQDLSLHNAIRILDTAEEMSAVGDREVKKLPALRGRTVVNLFFEDSTRTRISFEAAAKRLSADVINFAAKGSSVSKGESLKDTAQTLSAMGADAVVIRHWASGAPHRLAATDWIDAGVINAGDGTHEHPTQALLDAFTMRRHWAKLSGTPSEGADLKGMRVAIAGDVLHSRVARSNVWLLRTLGAEVTLVAPPTLLPIGVEKWPCAVSYDLDETLARGVDAVMMLRVQGERMNASFFPSTREYSRRWGFDDNRLRALDSLGMKDTIIMHPGPMNRGLEISAAAADSPRSTVLAQVRNGVSVRMAALYLLLSGDTRETAAPPVLAAAGTAHSTKESI
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: REV_HV1RH
Sequence: MAGRRGDSDEDLLKAVRLIKSLYQSNPPPSPEGTRQARRNRRRRWRERQRQIRRCSEWILDTYLGRSVDPVQLQLPPLERLTLDSSEDCGTSGTQGVGSPQVLVESPAVLESGAKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: RECR_LEGPL
Sequence: MDALSRLVEALRCLPGVGPKSAQRMVFHLLQHQRQRGLHLASCLEQAMKHISHCQQCNNYTEQTLCTLCQNPNRDSTLLCVVESPADVSAIEQSNSFQGKYFVLMGKISPLDGLGPDDIGLPKLKELIIREKIQEVILALSPSVESQTTIHFIHQLLKDETVNISQLAHGIPSGGELEFLDGNTISSALKNRAVINV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TYSY_BUCBP
Sequence: MKSYLVLLKKILKEGSNRKDRTGIGTLSVFGYHMEFNLKLGFPLITTKKCHFPAIVHELLWFLKGDTNIKYLNDHNISIWNPWADERGYLGPIYGEQWRSWKTKDGRVIDQIDNVIHLIKNNPNSRRIVVSSWNVGDLHKMALLPCHVLFQFHVVDHVLHCQLYQRSCDVFLGLPFNIASYSLLTHMIAQQCNLKVGNFIWTGGDVHLYKNHIKQAKKQILRRPYLLPKLVINRKPTQIFNYLLQDFNLLNYKYHPSIHAKIAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WECG_ECO27
Sequence: MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAINAEKILTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMARAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASGAQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWLYRLLSQPSRIKRQLRLLRYLRWHYTGNL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: DAPH_STAES
Sequence: MVQHLSAQEIIQYISDAKKSTPLKVYVNGHFENVTFPESFKVFGSEHSKVIFCEANEWKQFYQQNHSLITELEIEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAIVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVVIEDNVLIGANAVILEGVRVGAGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQTSEVQDSKREIVSALRKLNNE
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: ACPS_METPP
Sequence: MIFGIGTDICDIRRLRATYARRGERFAEKVLGPQELEVFRYRLAKVEARGLSYLATRFSAKEAFSKAIGTGMRTPMSWRACQILNARSGKPEIRLHGPLAAWFEAQGLRAHVSVTDETDYAASFVVVETQET
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB6_PANGI
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTDAFASVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLAVLTASFGVTGYSLPRDQIGYWAVKIVTGVPEAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFPMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: IRF5_MOUSE
Sequence: MNHSAPGIPPPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFYIPWRHATRHGPSQDGDNTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFQLFYDGPRDMPPQPYKIYEVCSNGPAPTESQPTDDYVLGEEEEEEEEELQRMLPGLSITEPALPGPPNAPYSLPKEDTKWPPALQPPVGLGPPVPDPNLLAPPSGNPAGFRQLLPEVLEPGPLASSQPPTEPLLPDLLISPHMLPLTDLEIKFQYRGRAPRTLTISNPQGCRLFYSQLEATQEQVELFGPVTLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCALAHGSCPNPIQREVKTKLFSLEQFLNELILFQKGQTNTPPPFEIFFCFGEEWPDVKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDHMVEQFKELHHLWQSQQQLQPMVQAPPVAGLDASQGPWPMHPVGMQ
What is the function of this protein?
Transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 (PubMed:15665823).  Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters (PubMed:15665823).  Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction downstream of the TLR-activated, MyD88-dependent pathway (PubMed:15665823).
What are the official names of this protein?
Interferon regulatory factor 5, IRF-5.
What is the protein family that this protein belongs to?
Belongs to the IRF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm: upon activation by the TLR adapter MYD88 and subsequent phosphorylation, translocates to the nucleus.
Protein: Y535_LACJO
Sequence: MSDNNIKIIIAPAKKMRVDQDTFLVKSEPAFLDKTQELLDFLKTRSFNQLQDLWKANDNIVRTNQHNLVTSELDSNLTPALLAFSGIQYQYLAGDVLPQEGLDYLQDHLRILSGFYGILRPFDGIIPYRLELKTQMTGFKYYSLYNFWKDLPYQELFADTDTVINLASLEYSRLISPYLKDSQKMITIKFLENKNGKWRQSATHAKMARGEMVRFAAKEGINRPEDLKEFSDFGYVFSAADSTKENYIFKKL
What are the official names of this protein?
UPF0246 protein LJ_0535.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: XAPR_ECOLI
Sequence: MERVYRTDLKLLRYFLAVAEELHFGRAAARLNMSQPPLSIHIKELENQLGTQLFIRHSRSVVLTHAGKILMEESRRLLVNANNVLARIEQIGRGEAGRIELGVVGTAMWGRMRPVMRRFLRENPNVDVLFREKMPAMQMALLERRELDAGIWRMATEPPTGFTSLRLHESAFLVAMPEEHHLSSFSTVPLEALRDEYFVTMPPVYTDWDFLQRVCQQVGFSPVVIREVNEPQTVLAMVSMGIGITLIADSYAQMNWPGVIFRPLKQRIPADLYIVYETQQVTPAMVKLLAALTQ
What is the function of this protein?
Positive regulator required for the expression of xapA and xapB.  Binds to the inducer xanthosine.
What are the official names of this protein?
HTH-type transcriptional regulator XapR, Xanthosine operon regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: CYB_PLABE
Sequence: MNYNSINLVKTHLINYPCPLNINFLWNYGFLLGIIFFIQILTGVFLASRYSPEISYAYYSIQHILRELWSGWCFRYMHATGASLVFFLTYLHILRGLNYSYLYLPLSWISGLIIFALFIVTAFIGYVLPWGQMSYWGATVITNLLSGIPSLVIWLCGGYTVSDPTIKRFFVLHFILPFVALCIVFIHIFFLHLHGSTNPLGYDTALKIPFYPNLLSLDVKGFNNILILFLIQSIFGVIPLSHPDNAIVVNTYVTPLQIVPEWYFLPFYAMLKTIPSKNAGLVIVIASLQLLFLLAEQRNLTTIIQFKMVFSAREYSVPIIWFMCSFYALLWIGCPLPQDIFILYGRLFIILFFSSGLFSLVQNKKTHYDYSSQANI
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UNG_STAHJ
Sequence: MEWSEIFHDITERHDFKEMHDFLEKEYTTQTIYPDRDNIYQAFDLTPFEDVKVVILGQDPYHGPNQAHGLAFSVQPSAKFPPSLRNMYQELEDDIGCHRTSPHLQDWAREGVLLLNTVLTVRQGQAHSHKDIGWETFTDEVIQAISKYRDDVVFILWGKPAQQKIKLIDTSKHYIIKSPHPSPLSAYRGFFGSKPYSKTNDYLVSKGKSPINWCENGED
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAT_GEOSE
Sequence: MKLAKRVASLTPSATLAITEKAKELKAAGHDVIGLGAGEPDFNTPQHILDAAIKAMNEGHTKYTPSGGLPALKEEIIKKFARDQGLDYEPAEVIVCVGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGVPVYVEGLEQNHFKITPEQLKQAITPRTKAVIINSPSNPTGMIYTAEELKALGEVCLAHGVLIVSDEIYEKLTYGGAKHVSIAELSPELKAQTVIINGVSKSHSMTGWRIGYAAGPKDIIKAMTDLASHSTSNPTSIAQYAAIAAYSGPQEPVEQMRQAFEQRLNIIYDKLVQIPGFTCVKPQGAFYLFPNAREAAAMAGCRTVDEFVAALLEEAKVALVPGSGFGAPDNVRLSYATSLDALETAVERIHRFMEARA
What are the official names of this protein?
Aspartate aminotransferase, AspAT, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_MYCMS
Sequence: MSTEIQKIEDNNLKESQMWNSKELKEAIKEIEKMFGKGSIMVLGQSDNLNVETFSSGSLLLDNALGIGGYPKGRIIEIYGPESSGKTTLSLHAICEIQKLGGIAAFIDAEHSLDPKYCHNLGIDTNKLLVSQPDNGEQALDILEMLINSNSIDLIIVDSVAALVPKTELEGEMSDQSIGLQARMMSKALRKLNGLIAKSNTTVIFINQLREKIGVIFGNPETTTGGKALKFFSSIRLEVRKSENILSNSEIIGNKIKIKIVKNKTAIPFKTATISLLYNKGIDKIGELVDLLVSYEIVEKSGVWYSYQNEKIGQGKTSVIQWLNADEKRTNELIQQVKKIIEQKE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG32_YEAS7
Sequence: MVLEYQQREGKGSSSKSMPPDSSSTTIHTCSEAQTGEDKGLLDPHLSVLELLSKTGHSPSPMGQNLVTSIDISGNHNVNDSISGSWQAIQPLDLGASFIPERCSSQTTNGSILSSSDTSEEEQELLQAPAADIINIIKQGQEGANVVSPSHPFKQLQKIISLPLPGKEKTPFNEQDDDGDEDEAFEEDSVTITKSLTSSTNSFVMPKLSLTQKNPVFRLLILGRTGSSFYQSIPKEYQSLFELPKYHDSATFPQYTGIVIIFQELREMVSLLNRIVQYSQGKPVIPICQPGQVIQVKNVLKSFLRNKLVKLLFPPVVVTNKRDLKKMFQRLQDLSLEYGEDVNEEDNDDEAIHTKSRSYCRNKKAENSKKKSPKSNKKPKRKKQKFFTSWFTWGISITIGISFGCCVTYFVTAAYEHQTVKSLSLRPSILASLLSLDSSSDTINTPATASPSSTEQFLWFDKGTLQINFHSDGFIMKSLTIIKETWGKMNTFVLHALSKPLKFLENLNKSSEFSIDESNRILALGYILL
What is the function of this protein?
Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria.  Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Recruits ATG11 to the surface of mitochondria.  Promotes also autophagy-dependent peroxisome degradation (By similarity).
What are the official names of this protein?
Autophagy-related protein 32, Extracellular mutant protein 37.
What is the protein family that this protein belongs to?
Belongs to the ATG32 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Vacuole membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass membrane protein. Note=Is recruited to the preautophagosomal structure during mitophagy and imported into the vacuole along with mitochondria during starvation.
Protein: SIGI5_ACET2
Sequence: MLFVSAIIDYAGETATHIVEKIKNGDKHLKEKFIKDYIPFILNIVSSFYSSKTGDLKSSDEYSIGLMAFNEAIEKFDVNKSKSFLKFAEMVIKKRMIDYFRKTSSIGRKEIPFSYFNSNNETEFRKKINNLDIEEEFNSYEFICELRDFSKKLESFGLSINNLPDYMPKHKDSREMCINIAKKIVENKSIFDKLKTKKYIQMKELSKIIDVHPKTVERNRAFIICLCILFDNDYGNFKSYLNKIF
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity).  This sigma factor is involved in regulation of cellulosomal genes via an external polysaccharide-sensing mechanism (Probable).
What are the official names of this protein?
RNA polymerase sigma factor SigI5.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. SigI subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLBB1_TRIST
Sequence: MGRFIFVSFGLLVVFLSLSGTGADCPSDWSSYDLYCYRVFQEKKNWEDAEKFCRQQHTDSHLVSFDSSEEADFVASKTFPVLNYDLVWIGLGSVWNACKLQWSDGTELKYNAWSAESECITSKSIDNQWFTRSCSQTYPFVCKFQA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec stejaggregin-B subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH2_STRP2
Sequence: MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAIQAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKGLNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSPQPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDFATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CORA1_RAT
Sequence: MGLARATAGLGPCCPPAPALLGAGLRWGGFLFAWILVSFSCHLASTQGAPEDVDVLQRLGLSWTKAGGGRSPAPPGVIPFPSGFIFTQRAKLQAPTTNVLPTTLGRELALVLSLCSHRVNHAFLFAIRSRKHRLQLGLQFLPGRTLVHLGPRQSVAFDLDVHDGRWHHLALELRGRTVTLVTACGQHRVPVPLPSRRDSMLDPQGSFLLGKMNPRAVQFEGALCQFSIHPVAQVAHNYCAHLRERCRQVDTYGPQVGALFPWDSGPAFALHPEPALLGLGNLTRNPATLGSRPISRGLMVTMAPAVPTKPLRMVHQDVSKLGSSQTPLVPAKQSARKTPSPFPSAALANSTRVFHSAPAQPRQITATSPTKRPPTKPSVSSLSVTPMKSPQAIQKAGTPSFSRPIPTTQKPTPLTSHPSPSKVSSATVRPVQKTFMTPQPPTLSPQALHPITGLPKKFTIPTVAKPQSKMTSWASKPVLARTNVPKALEQTVVAQSSVSYLGSQTLATALPPLGVGNSRMMPSTRDSTSTPAGSKKITGLEASKKTRHKSSPRKPIPLSSGKTARDASPRDLTTKPSQLSTPALVLAPAHLLSSSPQPTSSSFSFFHLPEPTPFLMLMGPPGSKGDCGLPGPPGLPGLPGSPGPRGPRGPPGPFGNPGLPGPPGAKGQKGDPGLSPGQAHDGAKGNMGLPGLAGNPGPMGRKGHKGHPGAAGHPGEQGQPGPEGSPGAKGYPGRQGFPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGIPGKRGEMGRPGFPGDFGERGPPGLDGNPGEIGLPGPPGVLGLLGDMGALGPVGYPGPKGMKGLMGGVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSHGLPGFPGARGKPGPMGKAGDKGSLGLPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPPGQLGPEGDEGPMGPPGVPGLEGQPGRKGFPGRPGLDGSKGEPGDPGRPGPVGEQGLMGFVGLVGEPGIVGEKGDRGVMGPPGAPGPKGSMGHPGTPGGVGDPGEPGPWGPPGSRGLPGMRGAKGHRGPRGPDGPAGEQGSKGLKGRVGPRGRPGQPGQQGAAGERGHSGAKGFLGIPGPSGPPGAKGLPGEPGSQGPQGPVGPPGEMGPKGPPGAVGEPGLPGDSGMKGDLGPLGPPGEQGLIGQRGEPGLEGDLGPVGPDGLKGDRGDPGPDGEHGEKGQEGLKGEEGLPGPPGITGVRGREGKPGSQGEKGQRGAKGAKGYQGQLGEMGIPGDPGPPGTPGPKGSRGTLGPMGAPGRMGAQGEPGLAGYNGHKGITGPLGPPGPKGEKGEQGEDGKTEGAPGPPGERGPVGDRGDRGEPGDPGYPGQEGVQGLRGEPGQQGQPGHPGPRGRPGPKGSKGEEGPKGKPGKAGASGRRGTQGLQGLPGPRGVVGRQGPEGMAGQDGNPGRDGRPGYQGEQGNDGDPGPVGPAGRRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGGTGLPGNQGEPGSKGQPGDSGEMGFPGVAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIIGPPGMLGPSGLPGPKGDRGSRGDWGLQGPRGPPGPRGRPGPPGPPWHPVQFQQDDLEAAFQTWMDAHGAVRLEQGYSYPDQLMLDQGGEIFKTLHYLSNLIQSIKTPLGTKENPARVCRDLMDCEQKMADGIYWVDPNLGCSSDTIEVSCNFTHGGQTCLKPITASKAEFAVSRVQMNFLHLLSSEGTQHITIHCLNMTVWQEGPARPSARQAVRFRAWNGQVFEAGGQFRPEVSMDGCKVHDGRWHQTLFTFRTQDPQQLPIVSVDNLPPVSSGKQYRLEVGPACFL
What is the function of this protein?
Plays a role during the calcification of cartilage and the transition of cartilage to bone.
What are the official names of this protein?
Collagen alpha-1(XXVII) chain.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Found on some small banded collagen fibrils and meshworks.
Protein: RS12_PROMA
Sequence: MPTIQQLIRTERQRLTRKTKSPALRSCPERRGVCTRVYTSTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIIRGTLDTAGVKDRRQARSKYGAKAPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.