PharMolix/UniProtQA huggingface dataset:
Protein: ATG2_CHAGB
Sequence: MASFFQSFRSSSMAKQLLRFALSRLDLLDTQALDLENLDFALGRNTVLEFRDVGLILQKLERLLGLPPAFSLQKAKVLILRVTIPMDFYASPITAEIDGVDIRLKVASKKEKDRQDAGKRGKGMAGSEAVPTAADLAQSFLETQPVAEKEELEQALAAETQDLAASMAASEPESDDDSPVGTGQPLSLPVFLTNFLHGIVDRIQIRVQSVTFQADVEVAVDSNSPVPEPVTFQLSLDNINVEGVTSTSETPDEASTIVHKEGKRHVLLDNIRAALITETNVLSSLARSASMPSSSASRSPVAPRSPVDNETTAFNPSGLSRSVGSSAMAGSRDSSDDLPQSQHLQDNEAAFNIPYDFGDSNEPNEADEASPLSTPRASLYRGSPPPTITDHAKSAVLEPSPLIWSTAEREAQSVPFLRPPEGFPLSNDPSPAASVHSSSTNRSSGSSARDDLAESHIYSHEDAESMYMSAFSQTGSQGLRTGMPGAWDAFDDAEESETEAGPSTSTQAAPYDGSFDPPQPDRIPSPEQPSQDQKRNSPSFYAQDSSAEVPEPPQDDIPTPRGPTRLVKQLLSLSSISIYLPSSHKHVKIDTPDDGKSISPNIPGAFSMHSAAATSPKPTPADEPAGETTPIDPSIEIVLKPVEIQFDASIGFLLAMVVAQLLEAAQGGSKDAAGPTAAKPPSASPDVKVTVEQLSVLFLEKLAGVADVPQRFFEKSTPDLSSDVLLQAQVVDLRGSVSHDGPQTEMDFSIEKLKFGYANDDIVSFDRSVLMFESVANTFPSAGQDISVKATMGPEISRLEVNTLPLYVQLDLQKLDEVFGWFGGLSSFLNMGTSITANTSRADKSPANPVQKPKGVRFDEPVHPDDQAVTRENKTDLRINGLQVDVLGKDCSVMLNTSAFKLVSREGGIGIHLSRIRLSGPYFKNSRAEPPIVSEVLDTRVEFLPSPRAKDLERLLELITPSSNKFDEDEDEIMVDTLLRQRRKGSVLSLAIGKVRFDAGNLPQLTCLPSLIDDLAKLGTVAKYLPEDDRPGLLTLCHVKNAECRVDFGGRFGAILTSLTDLEVAHISMPQLAAVALGEIAVTRNKIEELVVTSPPPQTGPWQNLPVFRLRLIDDMEPVLKIKLMGLGLEYRVPTIMDLLNLGQDVTPEDYEAGLAASVASLGEQAHTVIKRASSGSLTSTGQAKAPRSLKVDVAFRDCLIGLNPLALPSKLTVALTDAHLEMVPGPQELVAVTTMKRVSVLLIDDISILESPGVRFTTSRRPPVVISTQVAELCTMGYVNICQISSAKATVTVSRDSQGDTQLEVEVRDDLLVLETCADSTQTLITLANALTPPTPPSTEIKYRTTVFPVEDLLASIRAETFGRAEGEYDLDNDFDVPQELGDDADSDLDFDAGPSDSPLNLDSQYLEENIVQEELFDATSSSMLREGATKFEDTNDGVLLSTAGLDNPSSSGLEISSSDLSITDDYFDKGPVGRGTAHRWDSKTDRYDQHNEIKLQRSPLKLCVRDVHVIWHLFDGYDWERTREVIAKAVKEVEAKAYERRAKTDRRGGFDPEFGEDEPIIGDCLFNSIYIGIPSNRDPKELAQAINHGLHDFGDTESIATSTVTTSTLRAAGQRRRSKSLRLDRSRRHKITFELKGVSADVVMFPPGSGETVNSLDIRLRDVDVFDHVPESTWKKFATYDLDAGERELGADMVHAEIITTKPADTPATEMVISATILPLRLHVDQDALDFITRFFTFRDETAPIHASPSDVPFIQRIVVNSIPIQLDFKPKRVDYAGLRSGKTTEFMNFMILEGARLVLRRVILYGVSGFDRLGDQLNDIWTVDVKRNQLPGVLAGLAPVRSLVNAGSGFRDLIEIPIREYRKDGRIVRSLRKGATAFAKTTGTEVVKLGAKLAIGTQNVLQGAEGLLVPQTGESSSNAAAVAAVLGDDWDEAEYEEEINRKFSLYADQPLGIVQGVRGAYASLARDLSVARDAIIAVPAEIMESEGAQGAAAAVLKKAPTIILRPAIGATKAIGQTLLGATNSLDPMHRKRVDAKYKKH
What is the function of this protein?
Lipid transfer protein required for autophagosome completion and peroxisome degradation.  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  ATG2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region.  The latter binding is assisted by an ATG18-PtdIns3P interaction.  ATG2 then extracts phospholipids from the membrane source using its NR and transfers them to ATG9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
What are the official names of this protein?
Autophagy-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: ARGB_BRASO
Sequence: MTDATTISPLDQARILSEALPHMQEYDDETIVIKYGGHAMGDEDTAKAFARDIVLLEQTAINPVVVHGGGPQIATMLKRLGIVSEFAAGLRITDAATIEIVEMVLAGSINKQLVGYINEAGGKAVGLCGKDGNMVRAVKATRTMVDPDSHIEKVVDLGFVGEPDKVDLTLLNQLIGYELIPVLAPLATSKEGQTFNVNADTFAGAVAGALKAKRLLLLTDVPGVLDKSKKLIPEISIKDARKLIADGTISGGMIPKVETCIYALEQGVQGVVILDGKVPHAVLLELFTNQGTGTLIHK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFNT5_SHEEP
Sequence: MAFVLSLLMALVLVSYGPGGSLGCYLSQRLMLDAKENLKLLDRMNRLSPHSCLQDRKDFGLPQEMVEGDQLQKDQAFPVLYEMLQQSFNLFYTEHSSAAWDTTLLEQLCTGLQQQLDHLDTCRDQVMGEKDSELGNVDPIVTVKKYFQGIHDYLQEKGYSDCAWEIVRVEMMRALTVSTTLQKRLTKMGGDLNSP
What is the function of this protein?
Paracrine hormone primarily responsible for maternal recognition of pregnancy.  Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium.  This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity.  This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus.  In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties.  In contrast with other IFNs, IFN-tau is not virally inducible.
What are the official names of this protein?
Interferon tau-5, IFN-tau-5, Antiluteolysin, P5, Trophoblast antiluteolytic protein, Trophoblast protein 1, TP-1, Trophoblastin.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the uterine lumen.
Protein: CFAI_RAT
Sequence: MKLALLILLLLNPHLSSSKNTPASGQPQEDLVEQKCLLKNYTHHSCDKVFCQPWQKCIEGTCACKLPYQCPKAGTPVCATNGRGYPTYCHLKSFECLHPEIKFSNNGTCTAEEKFNVSLIYGSTDTEGIVQVKLVDQDEKMFICKNSWSTVEANVACFDLGFPLGVRDIQGRFNIPVNHKINSTECLHVRCQGVETSLAECTFTKKSSKAPHGLAGVVCYTQDADFPTSQSFQCVNGKRIPQEKACDGVNDCGDQSDELCCKGCRGQAFLCKSGVCIPNQRKCNGEVDCITGEDESGCEEDKKNKIHKGLARSDQGGETEIETEETEMLTPDMDTERKRIKSLLPKLSCGVKRNTHIRRKRVVGGKPAEMGDYPWQVAIKDGDRITCGGIYIGGCWILTAAHCVRPSRYRNYQVWTSLLDWLKPNSQLAVQGVSRVVVHEKYNGATYQNDIALVEMKKHPGKKECELINSVPACVPWSPYLFQPNDRCIISGWGREKDNQKVYSLRWGEVDLIGNCSRFYPGRYYEKEMQCAGTSDGSIDACKGDSGGPLVCKDVNNVTYVWGIVSWGENCGKPEFPGVYTRVASYFDWISYYVGRPLVSQYNV
What is the function of this protein?
Trypsin-like serine protease that plays an essential role in regulating the immune response by controlling all complement pathways.  Inhibits these pathways by cleaving three peptide bonds in the alpha-chain of C3b and two bonds in the alpha-chain of C4b thereby inactivating these proteins.  Essential cofactors for these reactions include factor H and C4BP in the fluid phase and membrane cofactor protein/CD46 and CR1 on cell surfaces.  The presence of these cofactors on healthy cells allows degradation of deposited C3b by CFI in order to prevent undesired complement activation, while in apoptotic cells or microbes, the absence of such cofactors leads to C3b-mediated complement activation and subsequent opsonization.
What are the official names of this protein?
Complement factor I, C3B/C4B inactivator.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: CP302_DROME
Sequence: MLTKLLKISCTSRQCTFAKPYQAIPGPRGPFGMGNLYNYLPGIGSYSWLRLHQAGQDKYEKYGAIVRETIVPGQDIVWLYDPKDIALLLNERDCPQRRSHLALAQYRKSRPDVYKTTGLLPTNGPEWWRIRAQVQKELSAPKSVRNFVRQVDGVTKEFIRFLQESRNGGAIDMLPKLTRLNLELTCLLTFGARLQSFTAQEQDPRSRSTRLMDAAETTNSCILPTDQGLQLWRFLETPSFRKLSQAQSYMESVALELVEENVRNGSVGSSLISAYVKNPELDRSDVVGTAADLLLAGIDTTSYASAFLLYHIARNPEVQQKLHEEARRVLPSAKDELSMDALRTDITYTRAVLKESLRLNPIAVGVGRILNQDAIFSGYFVPKGTTVVTQNMVACRLEQHFQDPLRFQPDRWLQHRSALNPYLVLPFGHGMRACIARRLAEQNMHILLLRLLREYELIWSGSDDEMGVKTLLINKPDAPVLIDLRLRRE
What is the function of this protein?
Required for CNS development; negatively regulates glial cell division in the embryonic midline.  Involved in the metabolism of insect hormones; responsible for ecdysteroid C22-hydroxylase activity.  May be involved in the breakdown of synthetic insecticides.
What are the official names of this protein?
Cytochrome P450 302a1, mitochondrial, Protein disembodied.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: PENA_PENCR
Sequence: MSHVVRPILIILASVAIYTKYYLSFQNGFIDLLSTMGSQGSLAGLQDGLRSHYTGLDPLDKFLKACNVFFWPIFHGTSPALSLYAIAFAGSMIPMWLILLMHTCVKSSIVEIVMINALTGLLVQGIGPGVMMCVLLAMRSTSMEEFAVTSIPAVSILGPNDLPLSLVVCYILPLALSSLPAPASISVPSKQLFIASWQGWPLYIALAVGIAHSLRYGYRRSRPQQLFRHAYAFALACSIISHVGLLLISFLSIYPKSPFLSLHSADLHPQSLLVPRLPWQEVKITSLESGVLRFLHWDYSISSTGALLWCYDVYWEDRMRGKGWIAFFSLSSQLATMSLAFGPCSVALALYWTALSKNLMKNEHVRKR
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of the indole diterpenes penitrems (PubMed:26213965).  The geranylgeranyl diphosphate (GGPP) synthase penG catalyzes the first step in penitrem biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (Probable).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase penC then forms 3-geranylgeranylindole (3-GGI) (Probable).  Epoxidation by the FAD-dependent monooxygenase penM leads to a epoxidized-GGI that is substrate of the terpene cyclase penB for cyclization to yield paspaline (Probable).  Paspaline is subsequently converted to 13-desoxypaxilline by the cytochrome P450 monooxygenase penP, the latter being then converted to paxilline by the cytochrome P450 monooxygenase penQ (PubMed:26213965).  Paxilline is converted to beta-paxitriol via C-10 ketoreduction by the short-chain dehydrogenase PC-15 which can be monoprenylated at the C-20 by the indole diterpene prenyltransferase penD (Probable).  A two-step elimination (acetylation and elimination) process performed by the O-acetyltransferase PC-16 and the P. simplicissimum ptmI-ortholog not yet identified in P. crustosum, leads to the production of the prenylated form of penijanthine (Probable).  The FAD-linked oxidoreductase ptmO then converts the prenylated form of penijanthine into PC-M5 which is in turn transformed into PC-M4 by the aromatic dimethylallyltransferase PC-22 (Probable).  A series of oxidation steps involving 4 cytochrome P450 monooxygenases (PC-21, PC-05, PC-23, PC-20) and a FAD-dependent monooxygenase (PC-14) are required for the transformation of PC-M4 to penitrems A and E.  Synthesis of these final products is proposed to proceed via penitrems D and C (PC-21, PC-05, PC-14) and penitrems B and F (PC-21, PC-05, PC-14, PC-23) (Probable).
What are the official names of this protein?
Terpene cyclase penA, Penitrem biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound ascI terpene cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IKBP1_HUMAN
Sequence: MSLQKTPPTRVFVELVPWADRSRENNLASGRETLPGLRHPLSSTQAQTATREVQVSGTSEVSAGPDRAQVVVRVSSTKEAAAEAKKSVCRRLDYITQSLQQQGVQAENITVTKDFRRVENAYHMEAEVCITFTEFGKMQNICNFLVEKLDSSVVISPPQFYHTPGSVENLRRQACLVAVENAWRKAQEVCNLVGQTLGKPLLIKEEETKEWEGQIDDHQSSRLSSSLTVQQKIKSATIHAASKVFITFEVKGKEKRKKHL
What is the function of this protein?
Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival.  Acts by enhancing RELA transcriptional activity (By similarity).
What are the official names of this protein?
Interleukin-1 receptor-associated kinase 1-binding protein 1, IRAK1-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the IRAK1BP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS9_TRIV2
Sequence: MVVAEANSGRAVYWGTGRRKSAVARVRLVPGTGQLIVNGKPGDLYFQFNANYLGVIKAPLETLGLENEYDILVKAEGGGLTGQADSVRLGVARALCQLDPENRPPLKTEGYLTRDPRAKERKKYGLHKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RLP24_PONAB
Sequence: MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKRRNPRKVRWTKAFRKAAGKELTVDNSFEFEKRRNEPIKYQRELWNKTIDAMKRVEEIKQKRQAKFIMNRLKKNKELQKVQDIKEVKQNIHLIRAPLAGKGKQLEEKMVQQLQEDVDMEDAP
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).
What are the official names of this protein?
Probable ribosome biogenesis protein RLP24, Ribosomal L24 domain-containing protein 1, Ribosomal protein L24-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ATPB_OLEA2
Sequence: MSNIGKITQVIGAVVDVEFADGNLPNILNALVIKNPNNADCPELICEVAQHLGDNVVRTIAMDATEGLVRGMEVTDTGNPIMVPVGSASLGRIMNVVGRPVDEMGDIDAAKSLPIHRPAPEFNEQNTNVELLETGIKVVDLLIPFPKGGKMGLFGGAGVGKTVILMEMINNIAKQHGGISVFAGVGERTREGNDLYHEMKDAGVLEKAALVYGQMNEPPGARARVALTALACAEYFRDEENQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLGTDLGGLQERITSTTKGSITSVQAVYVPADDLTDPAPATTFSHLDGTLVLSRQIAELGIYPAVDPLDSTSRILDPNVVGAEHYSVAREVQMVLQKYKDLQDIIAILGMDELSDEDKQTVARARRIQRFLSQPFHVAEVFTGTPGVYVKLEETIKAFRGILNGEYDHLAENDFYMVGGIEMAVERYNQRQQAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RSMI_STRP6
Sequence: MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFICAEDTRNTGLLLKHFDIATKQISFHEHNSYEKIPDLIDLLISGRSLAQVSDAGMPSISDPGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFEDKHHYTETQMFCESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSISEILSYLEETPLKGECLLIVAGAQVDSEIELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVNRQELYQQFHDL
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_PHOPR
Sequence: MNQNVNNAITMTVLGAGSYGTSLAISLARYGANVILWGHDAEHIAQLEIDRANEAFLPGVAFPESLILSADLEMAVQASRDLLVVVPSHVFGLVLSDVKPFLREDSRICWATKGLEPETGRLLKEVAVDAVGAEVPLAVLSGPTFAKELAAGMPTAIAVSSPDDAFVEDLQEKIHCSKTFRVYSNSDFIGMQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMCRLGAALGAQKETFMGMAGLGDLVLTCTDNQSRNRRFGLALGQGKSVDQAQIDIGQVVEGYRNTKEVWALAQRYGVEMPISEQIYQVLYQGKDAREAAKDLLARDKKYE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIX23_XENLA
Sequence: MAAPSEDVSCEDFTEFQEILRVMRTIDDRIVHELNTTLPTVSFAGKIDAGQTCKQLYESLQTAHTSRDKAIKRCIAQTSTAVNILQGERLKDSDNLTLIKLLRKEQSKLKFLKSELNVEEVVNDRSRKVFNERCRLHYKPPKME
What are the official names of this protein?
Protein MIX23, Coiled-coil domain-containing protein 58.
What is the protein family that this protein belongs to?
Belongs to the MIX23 family.
Protein: YJ255_YEAST
Sequence: MMPAKLQLDVLRTLQSSARHGTQTLKNSTFLERFHNNRIVFCLPFFLALFFVPVQKVLQHLCLRFTQVAPYFKIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKIFQISYRVPMIWLDVFQVFFVFLVISQHSLHS
What are the official names of this protein?
Putative UPF0479 protein YIL177W-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0479 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PTGDS_FELCA
Sequence: MAALHTLWMGLVLLGVLGVLQTRAQAQVSRQPNFQQDKFLGRWFTSGLASNSSWFREKKNALSMCISVVAPSAEGGLNLTTTFLRKDQCETRTLLLRPAETPGCYSYTSPHWGSTHDVWVVATDYEEYALLYTAGTKSPGQDFHMATLYSRTQTPRAEVKEKFSTFAKTRGFTEDAIVFLPKTERCMEEHR
What is the function of this protein?
Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation.  Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes.  Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter.  Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier.  It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system (By similarity).  Involved in PLA2G3-dependent maturation of mast cells.  PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity).
What are the official names of this protein?
Prostaglandin-H2 D-isomerase, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS, PGDS2.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum. Nucleus membrane. Golgi apparatus. Cytoplasm, perinuclear region. Secreted. Note=Detected on rough endoplasmic reticulum of arachnoid and menigioma cells. Localized to the nuclear envelope, Golgi apparatus, secretory vesicles and spherical cytoplasmic structures in arachnoid trabecular cells, and to circular cytoplasmic structures in meningeal macrophages and perivascular microglial cells. In oligodendrocytes, localized to the rough endoplasmic reticulum and nuclear envelope. In retinal pigment epithelial cells, localized to distinct cytoplasmic domains including the perinuclear region. Also secreted.
Protein: ACP_VIBC1
Sequence: MSNIEERVKKIIVEQLGVDEAEVKNEASFVDDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYVNSAQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADE_RALPJ
Sequence: MPISSALAERIATSPKAELHIHIEGSLEPELMFALAERNGVKLPYASVEEVRAAYAFDDLQSFLDLYYAGASVLLTEQDFYDMTAAYVARALADNVHHAEIFFDPQTHTARNVPMHVVIHGIVRALDDAEREHGFSSALILCFLRHLSEEDAFDTLEAALPYIQDPANRIIGVGLDSSERGNPPEKFARVFARCKELGLRLVAHAGEEGPAQYVIDALDILKVERIDHGVRAIDDAALVKRLAAERIALTVCPLSNEKLKVYPDLRDHSLKQLLDAGCAVTLHSDDPAYFGGYMNTNWLATFNALDLSAADAHALARNSFEASFLPEQDKALWLAKVDDHWKAAH
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: LPXK_CUPPJ
Sequence: MSAPRHDLADFVTAQWQRRGWFAWLMLPFSLLFGLIARVRRYGYLHGWFKSTRLPMPVIVVGNVTVGGTGKTPAVIALAQALTEAGLRPGVVSRGYGVTLKHPRRVKPTSKASDVGDEPLLIARAADVPVWVFPDRALCAQTMLVSHPGVNVLLLDDGLQHYRLQRDFEIVMFDSRMGGNGLMLPAGPLREPLSRPRDATLINDPNFRATPERPDVYGMRLDLDEAWQLNDPTMARPVSAFAGRRVLAAAGIGNPERFFASLRGAGLSPKTLPLPDHYDFAEDPFAGNPDALDADVILITEKDAVKCERFDDPRIWVVPTTPVIDAGLIDKIRRAVLARVPAAKSTPASGGATGLNKEHQDGQPAA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: DIK2B_MOUSE
Sequence: MESQWRGAAATAFHQHWLARLLLWVSTLSCSFSLPASLPPSLVPRVRSSYTMGKTFLGLDKCNACIGTSICKKFFKEEIRFDNSLASHLGLPPQDLHSYAANYSDDSKTWRPVEISQLVSRYQIEISDRRICASVSAPKTCSIERILQKTGRFQKWLQAKRLTPDLVQGLPSPFLRCPSQRLLDRVVRRYAEVVDAGSIFMDHFTAGDKLRLLYTLAVNAHPIILQIFPGAEGWPMPRYLGSCGRFLVSTSTRPLQEFYDASPEQAADLAYQLLRVLESLRSNDLNYFFYFTHVDAGMFGIFDNGHLFIRDASALGIIDKQEGSQAAARTGENEDIFSCLVSDCQIQLSSCDTVPEKQSLVLVCQQLLPQLLQGKFPSPVQKEIDSALSLCSKDNSTDLEVLGATSWLKDILRSLRTCDPRFAYRYPDCKYNDRF
What are the official names of this protein?
Divergent protein kinase domain 2B, Deleted in autism-related protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the DIPK family.
What are the subcellular locations of this protein?
Secreted.
Protein: NADD_CLOBM
Sequence: MINKAILGGTFDPIHNAHINVAYEALERFNLEEVIFIPAGNPPHKIKLKKTPAHIRYEMVKLAIEKETRFSISDFEIKSKDLSYTYRTLKHFKEKEPETNWYFITGEDCLSYLEHWKYIDEIFNICNFVIFSREGFKGKEEIIKKKKSMLLKYGKEILFMDASILDISSTKIRNRIKEGKEVSFYMPDKVYKFILQNNLYK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: FOLD_CLOBK
Sequence: MTKILYGNEVALKIKEDLNLRMDKLKEKNIIPKLAILRMGNKQDDIAYERSIIKSCEKLNIETKVEELNEDILEEDFLKLMENLNNEKDIHGILVFRPYPKHLNENIINSSIALNKDVDCMHPLNLERIFEGDLDGVMPCTPEAVIEILKYYDIDLKGKNIVIINRSMVVGKPLSMMVLSNNATVTICHSKTIDLPSITKKADIVVTAIGKAKLIKEEYFNENSIIIDVSINVDENGKLCGDVDFENVKEKVGAITPVPKGVGSVTTTLLLKHIVEAAERNS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DUS_STAAN
Sequence: MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEHPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTSKELLDLLRLHLSLFNKYEKDEIRQFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKIEL
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: PETN_HUPLU
Sequence: MDIVNIAWAALMVVSTFSLTLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.