PharMolix/UniProtQA huggingface dataset:
Protein: GMHA_YERPP
Sequence: MYHDLIRSELNEAADTLANFLKDDSNIDAIQRAAILLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHLSCVSNDFGYDYVFSRYVEAVGREGDVLLGISTSGNSGNIIKAIEAARAKGMKVITLTGKDGGKMAGSADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVKA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELU_SHEPA
Sequence: MTLNKVPASEYRRILVNDHPIMDARAPVEFEKGAFPASVNHPLMEDEERKKVGTCYKEHGQETAIKLGHSLVQGEIKQQRVDAWLDFFTKNPDGYLYCFRGGLRSQLTQQWLKEAGLDIPFIEGGYKAMRQFLIETIDNAANVKPMLILSGITGSGKTDFLLQRKEAVDLEGIAHHRGSSFGRYHEGQPSQINFENALAVALLKHQDTDAKHLLLEDESFLIGRSALPQAFYSGMQTASVLVLEESMDARLTRLLNEYVHKMHSGYIQRLGEEAGFEAFAQYLAQSITGIKKRLGGKQHDELQAMITDALSIQTSQNDTRGHLGWIELLLVKYYDPMYQYQIDKKAERILFKGDHQAMHQWLDDH
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: Y4FJ_SINFN
Sequence: MRMNFSTVLLGSSVALAAVSGAQAADAIVAAEPEPMDYVRVCDAFGIGYFYIPGTETCLKINGYARFQVSFGPDEVNKRQGWGAQGTSDWDAFSRAYIAFSAKSDTELGTLTGFFASEFNADNDSDVGDSLINLDEAYIQLGGFKAGFFYSWWDKGLNGETDSLANITEFNSIAYLYEGGAFQAGVAINELEGATTKANGIGVQGIVSATVGGVSIDLLGGYDTEVEEGAIRALVSAELGPGVFQIAGVWASDPNVYFAASEWTVATSYRYNATEKLAITPGLHYWGDYGFVSDADQWRGGLAVDYKITSGLASRVSVQYTSRDIGADTEDFVSGFVRLQRDF
What is the function of this protein?
May act as an outer membrane pore.
What are the official names of this protein?
Putative outer membrane protein y4fJ.
What is the protein family that this protein belongs to?
Belongs to the alphaproteobacteria porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: HTPG_BDEBA
Sequence: MAKQVQNFNAEIKQLLDIVIHSLYSHKEIFLRELLSNASDAIDKLKFNSLTHPSLLPENWQPAIRLEPNSETKTLKIIDNGIGMTQEEVVEFIGTIARSGAKAFMQMNAEMKTKPELIGQFGVGFYSAFMVADRVTLHTQKAGSNDGTVWESMGDGTYSLDSVPRPEGTGTTITLHMKDFKEEDEVQNFTDKWVLKSLVKKYSDFIAHPIKMMGETEEETLNSQKALWLKSPSEVTKEEYKEFYQHLTHDWNEPLRTVHYRAEGTMEFNALLYVPGKKPWNYNMRDMEYGLSLYIKRVFIMADCKDLLPPYLRFVKGLVDSSDLSLNVSRELLQQDRQVTQIRKNVTNKALSTLKDLLTKERSAYEDFWTEFGATLKEGLPSDAANKEKLQDLLLFHSTSSDKMTTMDEYVARMKETQKDIYYITGDSLSQVSNSPYLEKLKEKGFEVLLLVDPVDEWVVDALSEFKGKKLQSIMREGLDLDTAEEKQQKEQEKKQAEVTLKPVLESMKKTLESDVKDVVLSDRLTNTPACLVASSADPSAHMQKLMAQMGKEYAGQQVKRIMEINPNHPVFEKMLKASPEQQTKWAEILYAQALLTEGSNLPDPVKFSQQIAELMVQAADSTKH
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WECF_YERPG
Sequence: MITLTHVLGSDIPHHNLTVLRFFNDVLAKCLPVEQVRHFMVAAKETAPFSSFPQLDINTYSDKKALAEAVIARAQADRSARFFWHGQFNVTLWLALLSGKIKPGQVYWHVWGADLYEDAKSLKFRLFYLLRRIAQGRVGHVFATRGDLIHYQQRHPRVPASLLYFPTRMDPALTAINIDKPLAGPMTILVGNSGDTTNRHIEALKAIHQQFGPDVRVIIPMGYPANNEAYIEQVRQAGLALFSQDNLRILTEQIPFDDYLNILRECDLGYFIFNRQQGIGTLCLLTQFGVPFVLSRKNPFWQDLAEQHIPVFFYGDTLDEPMIREAQRQLAGLDKQAIAFFNPNYIEGWKQALALAAGEHP
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DTD_STRA1
Sequence: MKIIIQRVNQASVSIEDDVVGSIEKGLVLLVGIAPEDTTEDIAYAVRKITSMRIFSDDEGRMNLSIQDIKGSVLSISQFTLFADTKKGNRPAFTGAADPVKANQFYDIFNQELANHVSVETGQFGADMQVSLINDGPVTIVLDTKNK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA44_TRYB2
Sequence: MAAPAQAVVKEKPPIHVYPQAKIGTKIFTHHGIHSMRYNGVCALTGSTVLMASGRFVMFVDVHKGTIESMQGPENGGVGAVAVHPSRQYYVVCERKPSDPAIRAYSWPSRTEVGEFVKGATKGFSACAFNKDGSMMATVGMYPDFFLTVWDWESRGMVLRSKCHNTDVYTVLFSPFDSGLLVSGGAGHIKFWTMANTFTGLKLQGLLGKFGRLEISNVSGFVVLSDGKVISGSESGLIILWEGDLIRCCFAREVDREDDDGTAATFMARSYDYTPCHEGAINVVELMEGGRVLMTAGDDGYFRFWRVSELEVAEGEGAPPLYVPECLGEILVHAGAFIRSVTYCKDVDEWVVLDSAGVLWRVPYVHPDDILNNAVTKPKEQAVPALEFNGGSITSAALSPIDHTVVTGGEDGTIRLVDYVTPRELYKMCLPQPNVVIGLRFFQKDPEKKKFLACCKSGAVLLVKRGSTAFTLLGQWRPHNDGLALFAVDAAEHRLCTIAHGTVFFFTILDDFSSLEPIGFCKIPLPGATCVAWDDASSCCLIGFECGKLLAIRAPTRDMVDQSVSYEFTCNYALVGIRQRKKVEKKQANVSAGEREGFVEEEEEEEYLGPWPVRLICPMADGDFAIGAGGVELLYKYGLHVRYEGQKELPPLPPTGIEPPDYVEEPLMNLCYRDYTPEASSMSYSGRYLVVICEGSQMLLRQLDEMGRVRLEPILVASAHDRLDGPIAAACTSFDDKMLVSVGSDGLVVAQLLDGCIAPQPPSPVAQLQPLRAEEIVEPQLAPFSITEQKDLDDRRRAEDEKRRELNLFLDKLKDVHQKYARLLRENQSLALTHRLSKEEITIHPQIYRELQEEMRQRVEESRKPTALELARENIRTRKMRNRFVDNLAHDRFLVRSFSKEFSVASFRTPYVDGSIKLFQQQIDELLGSERCSSLACDGDRGIVSVASGEASQQSPRNLSLSTAAGVVRWLNSEERKRNEGEQQKMNAAHREAEILTTTMRQYLNKMDERREERHWRKKGYEMLLAHKPDPAVEEASLNEELRRETRRRGECILRTDPSYHSAPSAVIKLQQLIRLEEIIFNMRNNFSNELLKLRDEKERLCGTLNVSLQRIRAINEKLKDKSFHADDVKLTPEEMPGKRFEISRDGLVAFMKQRQEEKLREQTAKKAQRGFGADLATGEPATNTDTSGADTPATRRSEGEDSRKVTISANRDSFGTAAARTRSVRTGTLAASKGGRPFSGGGFAAGAARERMNHELRVKHENIKLTEMEEEELQIERNRLLAERQRLHTQVQAMMDEFDVRLWSMYEERSRVDANLCLAHTHSLLLFREYNILLVFRQKDFELQSSYDEARNSRDRCLREMEELQRLVQDQTASIEKLQEANKVFRREVEIFISNSFPAEHVPYITKVFLRQIKRRKHHSDMSGNDDDITSDDDDDDDMGEDEAWEEICPPNCSEERWCEVIEKREVRLDYVDAITEERRQLEATEQRIEEHKALADKNNAAVSTCLKAIEDFQGEKRKQLNMLETLVAMRCGQVRCLDEEGRCPDTFRRNDLVVVSDKVITGLHDRIRALAEEKHDRRGKLKSMVAEQQALQRERSEKQALHTQWEEKIYEAMLLKFGQIVNLEVLESSCGSREVEQLKERLRLEELSWEKELRKRDKKIAVLREKLHESLEYNTSLLQTIGDQESDRQSVERSLAQSTQKVVSKMYDSINVATEEDRSNLRLLIAAQQEEIDALRTEVALLRTKGGHVYAAAMAAGR
What is the function of this protein?
Flagellar protein involved in flagellum axoneme organization and function.
What are the official names of this protein?
Cilia- and flagella-associated protein 44, Component of motile flagella 7.
What is the protein family that this protein belongs to?
Belongs to the CFAP44 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Closely associated to the axoneme along the paraflagellar rod.
Protein: RLME_SHEAM
Sequence: MTAKKRSASSTRWMQEHFDDHYVKLAQKRGLRSRAAFKLEELQEKDHLIKPGMTVVDLGAAPGGWSQVAVKLVGDRGKVIACDILPMDPIVGVDFLQGDFREDAVLNALLERVGDEKVDVVLSDMAPNMSGSDGVDQPRAMYLVELALDMCHQVLAPNGSFAVKVFQGEGFDEYMKAVREAFKVVKTRKPDSSRARSREVYLVATGYKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_CORA7
Sequence: MITRLSELFLRTLREDPADAEVPSHKLLVRAGYVRRVAPGVYTWLPLGLRAMRKIEDVIRQEMNAIGGQEMLFPALLPREPYEESNRWTEYGDNLFRLKDRKGADMLLGPTHEEMFTTAVKDMYSSYKDFPVTLYQIQTKYRDEERPRAGVLRGREFTMKDSYSFDMTDEGLDESYARHRKAYQNIFDRLEIDYAICKATSGAMGGSASEEFLAVSEVGEDTFVRATEGEYAANVEAVVTQAPEEISFEGLPEAQEHETPKSETIESLVEWAKGAGITVDGREVTAADTLKCMMIKVAAPAATEEEKEWELAAVLIPGDRALDEKRLEASLEPAEFELAGEGDFKKNSFLVKGYVGPRVLNAHDVKVYADPRVVSGTSWITGADAPQRHVVGLVAGRDFTVDEFIEAAEVKEGDPAPNGQGTLTLERGIELGHIFQLGRKYTEAFDVQILDENGKRAVPTMGSYGIGVTRMLAVLAEQRHDEKGLNWPVAVAPYQVHVAVANKDAAALEAGQKLVEDLDRAGIEVLYDDRPKVSPGVKFKDAELLGMPFIAILGRAFADGIIELRIRGGETREVPADSIVDTLTELIRG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_HELP2
Sequence: MKLKSFGVFGNPIKHSKSPLIHNACFLTFQKKLGFLGHYHPILLPLESHIKNEFLHLGLSGANVTLPFKERAFQICDKIKGIALECGAVNTLVLENDELVGYNTDALGFYLSLKQKNYQNALILGSGGSAKALACELKKQGLEVSVLNRSARGLDFFQRLGCDCFMEPPKSAFDLIINATSASLNNELPLNKEVLKGYFKEGQLAYDLAYGFLTPFLSLAKELEIPFQDGKDMLIYQAALSFEKFSASQIPYSKAFEVMRSVF
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: VMAT1_MOUSE
Sequence: MFQVVLGAPQRLLKEGRQSRKLVLVVVFVALLLDNMLLTVVVPIVPTFLYATEFKDINSSLLRGPSVSSQQALTSPAFSTTFSFFDNTTMTVEEHVPFRVAWINGTIPPPVTEAGSVPKNNCLQGIEFLEEENVRIGILFASKALMQLLVNPFVGPLTNRIGYHIPMFVGFMIMFLSTLMFAFSGTYALLFVARTLQGIGSSFSSVAGLGMLASVYTDNYERGRAMGIALGGLALGLLVGAPFGSVMYEFVGKSSPFLILAFLALLDGALQFCILWPSKVSPESAMGTPLLTLLKDPYILVAAGSICLANMGVAILEPTLPIWMMQTMCSPEWQLGLAFLPASVAYLIGTNLFGVLANKMGRWLCSLVGMVAVGISLLCVPLAHNIFGLIGPNAGLGFAIGMVDSSLMPIMGYLVDLRHTSVYGSVYAIADVAFCVGFAIGPSTGGVIVPVIGFPWLMVIIGTINIIYAPLCCFLQNPPAKEEELAILNQECPTETQMYTIQRPTKEFPLGENSDDPGSEE
What is the function of this protein?
Electrogenic antiporter that exchanges one cationic monoamine with two intravesicular protons across the membrane of secretory and synaptic vesicles.  Uses the electrochemical proton gradient established by the V-type proton-pump ATPase to accumulate high concentrations of monoamines inside the vesicles prior to their release via exocytosis.  Transports catecholamines and indolamines with higher affinity for serotonin (PubMed:21712771).  Regulates the transvesicular monoaminergic gradient that determines the quantal size.  Mediates presynaptic monoaminergic vesicle transport in the amygdala and prefrontal brain regions related with emotion processing in response to environmental stimuli (By similarity).
What are the official names of this protein?
Chromaffin granule amine transporter, Solute carrier family 18 member 1, Vesicular amine transporter 1, VAT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Vesicular transporter family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Protein: HRCA_LISW6
Sequence: MLTERQLLIFRAIIDHFTWTIQPVGSKNLLKEKGLPYSSATIRNEMGVLEEYGFIEKTHSSSGRVPSEKGYRFYVDYLLQLKKLDKSDRQMIRSFFSENYYEMEGLIQNSALMLSDLTNYTSILLGPEATKNHLSGFRFVPINNFQAMLILITDQGHVDNHLVTIPEGTTLSDIERMVNILNERLVGLSLDDLKVQIPMEVKELLGKHVRNYESFMHVFSDSFAQASQQKVYFGGKTNILNQPEFHDINKVREMLHLMEEEQDVYELFRDIPDGLQVKIGRENNNSLMEDCSIITATYNIAGERVGGIVLLGPTRMEYNRMMGLVDVMSRDLTDVLTKLYRDNQN
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: UCP2_PONAB
Sequence: MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVHATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAACTSREAPF
What is the function of this protein?
Antiporter that exports dicarboxylate intermediates of the Krebs cycle in exchange for phosphate plus a proton across the inner membrane of mitochondria, a process driven by mitochondrial motive force with an overall impact on glycolysis, glutaminolysis and glutathione-dependent redox balance.  Continuous export of oxaloacetate and related four-carbon dicarboxylates from mitochondrial matrix into the cytosol negatively regulates the oxidation of acetyl-CoA substrates via the Krebs cycle lowering the ATP/ADP ratio and reactive oxygen species (ROS) production (By similarity).  Proton transporter activity is debated, but if it occurs it may mediate inducible proton re-entry into the mitochondrial matrix affecting ATP turnover as a protection mechanism against oxidative stress.  Proton re-entry may be coupled to metabolite transport to allow for proton flux switching and optimal ATP turnover (By similarity).  Regulates the use of glucose as a source of energy.  Required for glucose-induced DRP1-dependent mitochondrial fission and neuron activation in the ventromedial nucleus of the hypothalamus (VMH).  This mitochondrial adaptation mechanism modulates the VMH pool of glucose-excited neurons with an impact on systemic glucose homeostasis.  Regulates ROS levels and metabolic reprogramming of macrophages during the resolution phase of inflammation.  Attenuates ROS production in response to IL33 to preserve the integrity of the Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages (By similarity).  Can unidirectionally transport anions including L-malate, L-aspartate and phosphate (By similarity).  Does not mediate adaptive thermogenesis (By similarity).
What are the official names of this protein?
Dicarboxylate carrier SLC25A8, Mitochondrial uncoupling protein 2, UCP 2, Solute carrier family 25 member 8.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HSDL1_BOVIN
Sequence: MAAVDSFYLLYREIARSCNCYIEALALVGAWYTARKSITVVCDFYSLIRLHFIPRLVSRADLIKQYGRWAVVSGATDGIGRAYAEELASRGLNIVLISRSQEKLQMVAKDIADTYKVETDIIVADFSSGREIYDMIREALQDRDIGILVNNVGVFYPYPQYFTQVSEDTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATNVATPGSFLHKCPWLVPSPKVYAHHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANILNRSLRKEALSCKA
What are the official names of this protein?
Inactive hydroxysteroid dehydrogenase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: IF2_RHOPA
Sequence: MVDTKTPGDKTLTMPTKTLTLKPRVEQGVVRQSFSHGRSKQVVVEKRGKRRLGGDEPAAPAAPEVAKKPAPAPAAPPRQQQSRPAPQQSRSGMVLRTLTEDERTARATALADARVREIEERKQAEIEAQRRAEQEKIEKAEREAAEARRKAEEERHRQEDEAKRKAETEAKKRFGDAEPAKKPAETSTTTTTAAPARPATTTTRTPTPAGRPPAVAAEAGDDDEAPRMIRRPGGPARPAPPPKQPAAKPGASKQRGRLTVVTALNADDVRERSIASFRRRTQRLKGHASNEPKEKLVREVVIPEVIAIQELANRMSERAVDVIRLLMKQGAMHKITDVIDADTAQLIAEELGHTVKRVAASDVEEGLFDVVDDSTDTEPRSPVVTVMGHVDHGKTSLLDALRHANVVSGEAGGITQHIGAYQVTSPESGKKITFIDTPGHAAFTAMRARGAKVTDIVVLVVAADDGVMPQTIEAINHAKAAGVPIIVAINKIDKPDAKPDRVRTDLLQHNVQVESMGGDVVDVEVSAKNKINLDKLLEMIALQAEILELKTNTQRPAEGTVIEAKLDRGRGPVATVLVQRGTLRVGDIIVAGAEMGRVRALISDQGETVQEAGPSVPVEVLGFNGPPEAGDRLAVVENEARARQITDYRAHQKREKSAASVSGMRGSLEQMMTQLKTSGRKEFPLIVKADVQGSLEAILGSLEKLGTDEVAARILHAGVGGISESDVTLAEGFNAVILGFSVRANKEAAAAAKRNGIEIRYYNIIYDLVDDIKKAMSGLLAPTLRETMLGNAQILEIFNISKVGKVAGCRVTDGTVERGANVRLIRDNVVVHEGKLSTLKRFKDEVKEVVAGQECGMAFENYTDMRAGDIIECYRVETIQRSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_BURO0
Sequence: MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLILIGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVHKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRVFDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIVLTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAYVMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIFVAETLSVMLQVSWFKYTKKRYGEGRRLLKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLTTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
Protein: RL16_STAHJ
Sequence: MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEYGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ACKA_CHLT3
Sequence: MNILVLNCGSSSVKFRLIHTYFDLIRENKDYSIASGLIERVGSEGLLSFRSTNAQGEVLSTLRTTAPVRTHQAAIDQIIKWITSENSGIQGIQSLEDIHAVGHRVVHGGEKLTRSVLIDDSVVEQIEDCIELAPLHNPQNLKGIYAAKKTFGPNIPQVAVFDTAFHHTLPDHAYLYALPYQIYRRHRIRRYGFHGLSHRYVRFRYRTILGMERENVNIISLHLGNGCSACAIKNGNSIDTSMGMTPLEGLVMGTRAGDVDPAILTYLAHKEGHSLDDLDKLLNSQSGLLGISGLTNDMRELIEESLENDDRRAKLALEIFAYRIKKYVGAYLSAMNGADAIIFTGGIGENADFIRQKICAGMNWCGIEIDENLNKQTTRGREGRISPDGNKPEVWVIPTNEELVIARDTYRCVMRKE
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_STAEQ
Sequence: MAKKGKKYQEAASKVDRTQYYSVEEAIKLAKETSVANFDASVEVAFRLGIDTRKNDQQIRGAVVLPHGTGKSQRVLVFAKGDKITEAEEAGADYVGEADYVQKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVKKAVEEIKAGKVEYRAEKAGIVHASIGKVSFDEEKLVDNFRTLQDVLAKAKPASAKGTYFKSVAVTTTMGPGVKVDTSSFKL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: UREE_VEREI
Sequence: MLTVSRLIPRGQGLAPVLRQRASTVELDWELRQKSRLSATDSAGRALGIFLPRGTRLRGGDMLVAEDGSLVRVLATPQPVLLISACPKHGSPFDLTRAAYHLGNRHVPIELQPDHLKIEPDPVLADMLRALHLIVQADNLPFEPEGGAYAAGQGGGHGPHGQHTHPHH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO296_YEAST
Sequence: MNRTVSTLSSTVSDVSVEIPSICNVINTELPTSDVYLYTLKLILLDYINEPRFKEAALLSNRTGTSRVLSDKTNHQQTQHGKKLVVDKQDDMSERDIVQATLRILKGKLAQISGNKNLAPNEMHWKSIVKMYYSMLDSSSADTFSKMGQMEEVVGYFTNIASNELKKMTIKNSRDELFSEVAYFIDLVIDVLPDSCANIIKRLLDYKINLKKGETTVKKKRAASPATVPQYRSISGSTISNKQPSFKVQDISHMKYFMQLFETDETKLHQDVMAVKDDCTNPIFCGELRYLRKKIKKDNGTLTASDFSSDREYNLWKNYELLEIANLMDRFEIGEKVTSHGNRLIPKDAKSVFVRLIGLVLKKECSNAVNAINLSQEALFFFHKSARYWRIEYPSTISSLVYSAANLSVLGDEELNIPITENLFSVIRNKYLCSEDNLDPSAWNAQDRYLWAANLFHTTDQSMRTINNLLTAIFSGTKPKFSPVLSFYYSNIVGDPVMEFYETQSVAVKKYWIKLFKKTLFKASEDYFVSLLQDMLKANAIEIQNVQNLVETIIEAIKAIQKRYNKPLLDEISLPRQCAVFLCEVYGSDSLNLIKTAEKSTMKMTGQKLGPIDALDMYDVLKELRQIYLQVKPKGKFFFNLENYFIKYLTRLCDDVSRNVQKVIKSSLESENWQPVNDQDHFSRSVLDIFKMINESTSMLEKFGWQNEFQLAQMITVILKAFSDGMLSYSAQLMELIQRDLQEGDEPSYSLESSDTRSSLSLNNANVNHEKSRSSRLFEDLKNVVKSTPKMVAPAPYQFKKRTCVLLNDLDKTLFLLESFEEKADPSKISSVIAQYHSSHNLEDNGKSFDDQNMKQVYTLRIIGAENIKGFSKTGLSNTYVSMRNITLQREIGTTKIVARSITPKWDEEFVFESPFGKSNDIMFTIWHHPHSRLKNLAEDDLCGKANMKFTPRKLKDDGFPIDFSLTLNPQGTLYCQISLESEKIDAVSSMGRIYRSFSRSRDRAINLIVNKFSDFIAFAFSRTTLKTVCGHHGSALASDEAVYDAILPLFDYLNANLNILASELSQRLLFMVMLRAWNLVLENADLLLLPALNSAKVNILRSAKKSLWENTLSTTKTVSGYGRPLTQAEIEAVFKWLDALCVDFFHNKGEGPPLAELKNEYYQNILLIPAFYDKSVSELKDEVQRLIPLYEEYLRWFYLKKTPITFTNKSAGTISRKKSLVANIVKEPKEQLERDAEVMNIILRILIAKGQHDYVHRILHDRKELVNTMKNRRAVSRAVTPTGKKGRN
What are the official names of this protein?
Uncharacterized protein YOR296W.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UP01_LONON
Sequence: NSCDCDIEWSSCSAYGFDHDEDYGFNEDTDRIIINTKAILLPTK
What are the official names of this protein?
Unknown protein 1.
Protein: RLMG_PSEP1
Sequence: MPLLTTPYAELDLIRQPEQANDPLQAFDAADEYLLAQLHDQAPDANCRVLVLNDSFGALAASLAGQLQVVSSGDSHLGHLALEKNLARNGLPFDSVPFVPASEHWQGPFDRVLVRVPKTLALLEEQLIRLQGQLAPGAQVIAGAMIKHLPRAAGDLMEKYIGPVQASLALKKARLLTATVAERPLAKSPYPSCYRLDVPALDLINHANVFCREGLDIGTRAFLPHLPRDLGRARVADLGCGNGVLAIASALANPEAEYTLVDESYMAVQSAQENWLAALGERPATFFAADGLAGLEKQSLDVVLCNPPFHQQQVVGDFLAWRMFQQAREALVVGGALYIVGNRHLGYHSKLARLFRGVEQVAATPKFVILKARK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.