PharMolix/UniProtQA huggingface dataset:
Protein: AMPL_PLAVS
Sequence: MPLLRSSQHIKNTYWNIPKKSFRTGVPQFAESKKTRILHLHPLCKSASGVESPPFFDSQTFSSISNRKEFRKMATTVPQVVSLDPTTIPIDYHTPIDDLSIEVKDISAEACPADEGLIVFLLNSAPKHSSSGGSGGNGGSAGSSGNGEGGAQIKINSSVKDNTINEFLKEGNMENFTGKLGTSKSFYIANDQKKYVSLAYVGCGPANEETELEIRKVAYALVTLLHDSKHKKVSIIFEIKIEEALFRFFLEHLFYEYVTDERFKSADKSTETDFIKNLSLHIANADAYKGQIDKARVYFYGTYYAAQLIAAPSNYCNPVSLSNAAVELAQKVNLECKILDVKELEELKMGAYLSVGKGSMYPNKFIHLTYKGAQTGASQNEKKKIALIGKGITFDSGGYNLKAAPGSMIDLMKFDMSGCAAVLGCAYCIGTIKPDNVEVHFLSAVCENMVSKNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDYIVDIATLTGAMLYSLGTSYAGVFGNNDQLINKILSSSKTSNEPVWWLPIINEYRSSLNSKYADLNNISSSVKASSVVASLFLKEFIENTPWAHIDIAGVSWNFKARKPKGFGVRLLTEFVLNDAV
What is the function of this protein?
Aminopeptidase which preferentially cleaves leucine residues from the N-terminus of peptides (PubMed:19931315, PubMed:34133730).  Also, has some activity towards tryptophan and methionine and has very low activity towards alanine, arginine, asparagine, phenylalanine and tyrosine (PubMed:19931315, PubMed:34133730).  No activity towards histidine, serine, valine, isoleucine, glycine, aspartic acid and glutamic acid (PubMed:34133730).  In addition, cleaves the Cys-Gly dipeptide, probably as part of the glutathione regulation pathway; cleavage only occurs in the presence of Mn(2+) (PubMed:33303633).  Plays a role in the final step of host hemoglobin catabolism, by cleaving hemoglobin-derived oligopeptides providing a source of amino acids for the parasite protein synthesis and for the maintenance of osmotic homeostasis (PubMed:34133730).
What are the official names of this protein?
Leucine aminopeptidase, PvLAP, M17 leucyl aminopeptidase, Pv-M17.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
Protein: ARGR2_CLOPE
Sequence: MKSKRHSKIIEIIKSTAIETQEELAEELKKAGFDVTQATVSRDIKNLKLVKKQDNKGHYRYTIIEEEKNEMVDRLSNILANTVTSVENVDKMVVVKTISGSASAAAEAIDTLHLGEIAGTIAGGNTIFILVRSLEKAETLVSRILEMIEG
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_ECOLI
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35, Large ribosomal subunit protein bL35, Ribosomal protein A.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GPXA_NEIMA
Sequence: MGIYDFQMKDAEGNAVDLSGYRGKVLLIVNTATRCGLTPQYEALQKLYAQYTAEGLEILDFPCNQFREQAPESSGEIAQVCMMKFGTKFKIFDKIEVNGANTAPLYAYLKSVKPQDKGNHLFKDFVLKLAALGEKRDEGDIKWNFTKFLVNRDGEVVERFAPSVTPEEIEADIRALL
What is the function of this protein?
Important in the cellular metabolism or defense processes particular to this pathogen.
What are the official names of this protein?
Glutathione peroxidase homolog.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: GBPD_DICDI
Sequence: MTDYPFYKPDDETNIIYNININKKEGFSAIKSCSLAKLIEKLTSTKQLHTYFSSAFFLTYRDFTTPLEIINLLISRYTGPPPDSSKDSLRLFEIEVDIVQANVLSIFRTLIGTLIQVDFDTPKLSSSIIEFFNSLPESVKNELFLEFFKAKKMARPPGSIPKPVNSNIISSAASTMRFSYSVSPKTQSPNSTNNVLSGLLSNNGSNTMNGINGTSNNNVNSNNNNNNGTTNISSPNFDPSRSSMKMGKGIMKLLQSNIANFNNQQNGGGGGGSNNGTSPQSSPSSTLSSTNSLFNQQPSLSMLNDDGSVQNNNNNNNNNNNNNNVNEISTINVQLPPSTPPINGIPGEKTAFLPEAIAKELTIMEWELITALSVSDITSKEWNKSVNIQNLTTWFNRISSWVSTKIISKETPEERAIIIEAFINIANFAKELKNYNCVMEILGSLHGSSISRLKSSWALLSQKTNDMFQILNNLMTTDGNFKNYRKILTTVLPNEPCIPYLGLFLTDYTYLDESNPSLSTDSNLINIDRIFLISTRVQEFFQLFTNCNYTFISNMSVRDAILGEKVWDENEIFRLSKIREETSSLQSLKESNGIGNSNSTSGGSSSSLVNKDGSGGGGGSGGGGSVNSKGDGKGDGKDNRDGRGDGNSNCGNGSGISSKDKDLLLSSSSSAASHTVRRKNFVTKYRMSFTGNDPLPSVSSTLSEREWKILTTNSKTIIYPRGKTVLSVGETNTNIYRVISGRVKVETLKSFNSSDADLGAGGGGGGDNRGEDNSLMAIKARNRLSLNLPAQDDGYYVEEGEIFGQESFLYTDRPMLSNIIVDSGECELMEIEKSFVLQLFASEHQLSATFYKFIGVIQAQLLKSIYINFTSNYGNGGSGGSGSNGNGGGSSNGAGGGGLSSSVSIGNLNSPNINRIDFKRRSTIFETPSSLDILRDGNDSSFRTKFGLSQDEVIIKRYQCKHNNMNGTLYITKHNLCFEGKFLGINKNKTIPFDRTDKILTVDKNIMTVTTKEKVKKFTFKSHDDLNEGYGISVQIWANHLNINVKQQLQLQQQQLQQQQQQPSQQPSQQQSQSSQLQQSVSASSTTPPVPNSPKVGRGESFSNIKDLPSKDEWNQILKGTKPLTFKKGEILICEGVEYQKMFQIVKGECSVVKSLLPTPLDQNIFNNINNNNNNNNNNNNNNNNNNNNNNNNNNNGNNNNSIFKNNSSISNTNSNTSIDGGVGGGLSPQTLVDPKNSVIVSKLTHGSIFGEMSFLLPGGSATSLVVSSDEVEVYIIESYFLHILLKSKPYLASKFYKYLACVLETRVRNLT
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP (By similarity).  Induces the formation of substrate-attached pseudopodia, that leads to increased adhesion and thereby negatively influencing cell speed and polarity.
What are the official names of this protein?
Cyclic GMP-binding protein D, Guanine nucleotide exchange factor for rap1, Ras guanine nucleotide exchange factor U, RasGEF domain-containing protein U.
Protein: UVRB_ECO27
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
Plays a role in recovery after DNA ADP-ribosylation; a proportion of UvrB becomes immobilized on DNA in cells expressing DNA ADP-ribosyl transferase (darT) mutant G49D.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_ACIAC
Sequence: MASFLSFLLGEKKKTASVAKERLQIILAHERNGRNASEPDYLPALQRELVAVISKYVKISPEDLKVQLERQDNLEVLEVKIELPDTVR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: COX3_ELEMA
Sequence: MTHQMHAYHMVDPSPWPLTGALSALLMTSGLTMWFHYHSVILLLLGLTTNILTMFQWWRDVVREGTFQGHHTPIVQESLRYGMILFITSEVLFFTGFFWAFYHSSLAPTPELGSYWPPVGVYPLNPLEVPLLNTSVLLASGVTITWAHHSLMEGSRKNMLQALLITILLGVYFTLLQMFEYYEASFTISDGIYGSTFFVTTGFHGLHVIIGSTFLLICFIRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYLSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL36_DANRE
Sequence: MVVRYPMAVGLNKGHKVTKNVSKPKHSRRRGRLTKHAKFARDLIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNTLAAMRKAAAKKE
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL36 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Note=Detected on cytosolic polysomes.
Protein: SDHF3_YEAST
Sequence: MNNKLIYRSVRFATHNSQLLLPPLVLYRRILRQHKLLPGPQREMGDQYVRNEFKLHKDIDNPLHIVGFLASWQDYLHMISNGKWKDATLSSETLEKLSPEQTVQLYELMKETQKLHQDNEIESSKDVKRNNKD
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit SDH2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  Acts together with SDHAF1 (SDH6).
What are the official names of this protein?
Succinate dehydrogenase assembly factor 3, mitochondrial, SDH assembly factor 3, SDHAF3, Acetate non-utilizing protein 9.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion intermembrane space. Mitochondrion matrix.
Protein: ATPF1_CROS5
Sequence: MTSITGMIDPFLLLATESHAEGEALIGFHFDFLESNILNLAILVGVLVFYGRKVVGNILSERRNQIAQAIQEAEEKQRTAAQALAKEKENLAQAQKEAARIHEAAIERAKTLRAEIAAQSERDIARLKETAAADLSSEQERVMAQLKKQIAEQAIVKAESQLKAQVDNNTQQRLIDRSIARLGG
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CYSK_SYNY3
Sequence: MKIASNITELIGRTPLVRLNRIPLLEGCGAKIVVKLEGMNPAASVKDRIGINMINRAEQEGLIEPGKTLLIEPTSGNTGIALAMVAAAKGYQLILTMPETMSQERRAMLKAYGAKLELTPGSEGMGGCIRRAQELAESLPNAYMLQQFDNPANPQIHQQTTALEIWQDTDGAIDFLVAGVGTGGTITGVASVLKEKKPSFQAIAVEPQNSPVLSGGKPGPHKIQGIGAGFIPEVLDVNLIDEVIAVTDEEAIAYGRRLAREEGILSGISTGAALAAAIKVAKRPANKDKLIVMIQPSFGERYLSTPLFQDLE
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: RPOZ_FRATW
Sequence: MARVTVEDCLDKVETRFDLVVLASMRANKILKNGYSESMENEKKEKATVVALREIAESEITPEQILRNEIEG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: NRDH_SHIFL
Sequence: MRITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALRAQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAASA
What is the function of this protein?
Electron transport system for the ribonucleotide reductase system NrdEF.
What are the official names of this protein?
Glutaredoxin-like protein NrdH.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
Protein: LFTR_RHIME
Sequence: MKETRSKQPDITPDMLLRAYSIGLFPMADSADDPELFWVEPEIRGIIPLDRFHVSRSLAKAIRRRPFDIRFDTAFAEVMEGCAQPAPDRPTTWINDTIRSLYAALHNMGHAHSVEAWEGDALVGGLYGVSLGAAFFGESMFSRRTGASKICLVHLVERLRSKGFQLLDTQFTTEHLKSFGAVDVPKAQYEVLLAKAIASPNLEF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_SODGM
Sequence: MSKVLVVKSSILATFSQSNPLADHFIDQWREQHLNDDITVRDLGAQPVPELDGELVGALRPSDATLTQRQQQALELSDALIGELQANDVLVFTAPMYNFAIPSKLKNYFDLIARASVTFRYSEQGPERLVKNKRALILTTRDGIHKDTSSDLVTHYLRLFLGFIGITDVSFIYAEGVAYGPEAAVKAQEEAKASIQSFVSA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RPOZ_SYNP6
Sequence: MLQRFDLDSQDLLFKAESLIVNSTNRYHVTLQIARRAKQARYEEMENLSEETGIKPVLRAILEMSDELNQPEIIGG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: GCS23_NOCSJ
Sequence: MRIDFHASPEPTLGVEWEFALVDRRTRDLRNDATHLFARAKPRLPDPDKLHKELLRNTVEVVSGVCHTVGEAMADLRRTLEVVVPAGDDLDLDLYGGGTHPFASWTVQQLSEGHRYEELINRTQWWGRQMLIWGVHVHVGMPERDRVMAVLSSLLNFHPHLQALSASSPIWSGIDTGYASNRALMFQQLPTAGLPFQFERWSEFEAFVGDELVTGVIEELSEVRWDVRPAPRIGTLENRICDGVPDLADLSSLVALMHCLVVDLDTRAAAGETLPTMPPWHVQENKWRAARYGLDAIVITDAESNERLVTEDLADHLERLAPVADRLGCSEELAQVAQIPVRGASYQRQRAVAERTGGDLVAVVDSVVRELRAGLG
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-3, Gamma-glutamylcysteine synthetase 2-3, GCS 2-3, Gamma-GCS 2-3.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: YIDD_CLOP1
Sequence: MKKLFIVMIKFYRKYISPLKRPCCRFYPTCSQYALEAIQKYGAFKGGFMSIGRILRCNPFCKGGYDPVK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DAPA_LISMC
Sequence: MDLGKVITAMVTPIHPEKDKVCKKRIHHLVNHLIKNGSDGLVIAGTTGESPTLSHDEKIKLFRQVIETNDGRAKLIAGTGSNNTAETIAFTKEVAELGGIDAVLIVAPYYNKPNQDGLYAHFAAVSEASDLPVVIYNIPGRSVVNIEPETIIRLAKLPNIVGVKESSGNLDNISKIIAETSDDFQVYSGDDSLTLPILAVGGNGVISVASHVVGNEMQEMIQAFERGEVQKAAQIHRELLPLMNGLFSVPNPAPTKYLLNQQGISVGPVRLPLVDLNAEQGTKLQAILEGLSK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_HALH5
Sequence: MSKWLNVGKIVNTHGVRGEVRVLSTTDFEDDRFSSGKTLYVMRPNQNERVAVTVASHRKHKNFDLLCFEGYPSINDVEAFKGGRLQVPIEDRPELGEGEFFYHEIIGCSVVTIAGEELGKVKEILSPGANDVWVVQCRRGGKDLLIPYIEQVVKQVDLEKQQITIEPMEGLLE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
Protein: GCSP_BURCH
Sequence: MKLEHPDRLMNRTPLSLAALETHDAFAERHIGPDAASQQAMLDTLGFASRAALIDAVIPASIRRAETLPLGPFAQPKSEAEALAALRALADKNQVFRSYIGQGYHDTHTPAVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQQMVADLTGLAISNASLLDEATAAAEAMTLLQRTGKPKSNVFYVADDVLPQTLEVIRTRALPIGIEVKTGPAADAAQANAFGVLLQYPGVNGDVRDYRALTDAIHAAGGHVVVAADLLALTVLTPPGEWGADVAIGNTQRFGVPMGFGGPHAAYLAVRDEFKRQMPGRLVGVTVDAQGKPALRLALQTREQHIRREKATSNVCTAQALLAIMASMYAVYHGPHGLKTIALRVNRIAALLAAGVKQLGFATVNDTFFDTLTIDTGARTAQVHEFAKAKRINLRRVSDTQVGVSVDETTTRDDLADLLDVFAQAAGGTAPAVDALDAGLAGVAALPAGLERTSAYLTHHVFNRHHSETEMLRYLRSLSDKDLALDRSMIPLGSCTMKLNATSEMLPVTWPEFGGIHPFAPAEQTVGYREMIDQLEEMLVAATGYAAVSLQPNAGSQGEYAGLLIIHAYHASRGEGHRDVCLIPASAHGTNPASAHMAGMKVVVVACDAQGNVDIADLKAKAEQHSANLAAIMITYPSTHGVFEQNVREICEIVHAHGGQVYVDGANMNAMVGLTAPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGAHLAKFLPNQRSTGYARAEDGIGAVSAAPYGSASILPISWMYIAMMGAKNLTAATETAILNANYIAKRLAPHYPVLYSGPGGLVAHECILDLRPIKETSGISVDDVAKRLMDYGFHAPTMSFPVPGTLMVEPTESESQEELDRFIAAMIAIREEIRAVEEGRADREDNPLRHAPHTAAVVTANEWPHAYSREQAAYPVASLGTNKYWPPVGRADNAYGDRNLFCSCVPMSDYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: SYE_WIGBR
Sequence: MTVRTRFAPSPTGELHLGSIRTALYSWLFARKNNGEFILRIEDTDEERIKKISINNIIETMKLLGLNWDHGPYFQTKKLEKYNIIAKEMIYSGIAYKCYCSKNRINNLRIMQINKGEKPKYDGFCRNIEEKNIKNKRFVVRFSNPKNGYVIFNDLIRGTLKFKNSELDDLIILRSNKIPTYNFCSVIDDHDMNISHVIRGEDHINNTPRQINIFKALKIKCPKYAHISMILDKDRKKLSKKNQSTDVMKYIKNGFLPEALLNYLVRLGWSYGNQEIFNIDEMKKLFNLKSVGKSSCIFDINKLLWINQYYIQKLSDYDISSQIKKFFNKKEIDFNQGPKIENLIKIFKKKSRTLKEIFNQILFFYEDFSKVNFDLIKKYFTIDTNVHLKIFCKKLEKTSLWSVEEIKNTFFCTIKELNFNIKKIAMPIRIILSGSEHSPSIYSIIYSCGKLQTIKKIKIAIKFINDNKKKLNL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_BACSU
Sequence: MAIKKYKPTSNGRRGMTTSDFAEITTDKPEKSLLAPLHKKGGRNNQGKLTVRHQGGGHKRQYRVIDFKRDKDGIPGRVATVEYDPNRSANIALINYADGEKRYILAPKGIQVGTEIMSGPEADIKVGNALPLINIPVGTVVHNIELKPGKGGQLVRSAGTSAQVLGKEGKYVLVRLNSGEVRMILSACRASIGQVGNEQHELINIGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRKSPMSPWGKPTLGFKTRKKKNKSDKFIVRRRKNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2, BL2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CDKC3_ORYSJ
Sequence: MDGEEAPPGALNLADYAPAGARTVDCFRRIRKIGEGTYGEVFEAMDIITGERAALKKIKLDDGKEGFPRQILREIKLLKKLDHENIIRLKEIVVSPGTAHGAGGSDDYMYRGDIYMVFEYMDHDLKKVLHHSTPSQVKYYMEQLLKGLHYCHVNNVLHRDIKGANLLISGGGKLLKLADFGLARPFTRDGSFTNHVITLWYRPPELLLGATNYAEAVDIWSVGCIFAEFLLRKPLFPGRTEQEQLSKIFELCGFPNEENWPGVSKLPLYKTIRPTTPTKRRLRDIFHNFDSHAVDLIDRMLILNPTERISAHDALCAAYFITKM
What are the official names of this protein?
Cyclin-dependent kinase C-3, CDKC;3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: SFSA_SALNS
Sequence: MLFSPPLQRATLIQRYKRFLADVITPDGTTLTLHCPNTGAMTGCATPGDTVWYSTSENTKRKYPHTWELTETQSGAFICVNTLRANQLTKEAIQENRLPALAGYNILKSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKHLRELMGVAAAGHRAVVVFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAELSAQKMELNEPVPITL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: CRVP_TITSE
Sequence: MNLALFIIFATIFENVVPENCPKMYRRLSKSHTFCTPSTCKIEAGGKVTESDKQTILETHNQLRNKLATGKENQYQKLSSAANMMQMEWDDELAAVAQAHANQCKFEHDSGDQRAVGNFSVGQNLLETSGIFSIDWGKVKIWYTTEVDDFYPEYNKPFQFHGSYGHFSQVIWAKTWKVGCGVAGYVENGVKKVLYTCNYGPAGNLVGSEAYQVGSPCSACPENTKCSATYPGLCKSITPDGPQIRRPSSKDYLLYCDFSDKDPKACKDVTMTGSRPFTTQKLYTGKYVTQVFNAGENMTINFGKFEHKGGLCAFLIGRFGPNVAGETAASEVNFHFSAPHLIFPEGMKETRPITSWHTIGILMRWDKELQISYVFKVKPPTAKPPPQYFEFKEYGVKGGSCP
What are the official names of this protein?
Cysteine-rich venom protein, CRIVP, Cysteine-rich protein.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_SPHAL
Sequence: MANVTVIGSQWGDEGKGKIVDWLASRADAVVRFQGGHNAGHTLVVGEQVYKLSLLPSGIVTGTLSIIGNGVVLDPWALRDEITKLRGQGVEINADNFAIADNCALILPFHRDLDALRETAAGAGKIGTTGRGIGPAYEDKVGRRAIRVCDLAHLDHLEPQLDRLTAHHDALRAGFGEPPIDRDKLVADLREIADYVLEYAQPVWKRLKKVRKAGARILFEGAQGVLLDIDHGTYPFVTSSNTVSGTAASGSGLGPGAVGFVLGIAKAYTTRVGSGPFPTELEDETGQRLGERGHEFGTVTGRKRRCGWFDAVLVRQSCAVSGVTGIALTKLDVLDGFDTIRICTGYRLRGKILDYFPAHAADQAAVEPIYEEMDGWHESTAGARSYADLPAQAIKYIQRVQELIETPIALVSTSPEREDTILIRDPFSD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.