PharMolix/UniProtQA huggingface dataset:
Protein: MRAY_SALNS
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIARLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLIGYGIIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQLVVPFFKDVMPQLGLFYILLSYFVIVGTGNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL25_RHOJR
Sequence: MSDENRLVAAVRTEFGKGAARRARRDGQVPAVLYGHGEDPRHLNVPSRDFAAILRAHGTNAILTLDIEGKEQVALTKSVVVHPIRNYIEHADLLVIKKGEKVTVDVPVVVTGEAAAGTLVAQDAATISLEADALHIPEQIEVSVEGLEVGTQILANQLELPKGSTLQADEELLIVNVVAAPTAADLEEETGEAAAEAEAPAEEGAES
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: HYCI_ECOLI
Sequence: MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPENDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDQLKEDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEEE
What is the function of this protein?
Protease involved in the C-terminal processing of HycE, the large subunit of hydrogenase 3.
What are the official names of this protein?
Hydrogenase 3 maturation protease, HycI protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A31 family.
Protein: TIAS_THESM
Sequence: MVKLHIGIDDTDSPKGMCTTYLGALLYREISKIAEPLDLPKLIRLNPNVPYKTRGNGAVAMSFDAREEDILKIKNLVLEMVKKLSEFSHQNTNPGVVFIEGDIPEKLERFAYKAIWEHLNITDAENIAEELNAEIHKFRLGRGIIGALAAIGHPLKVFTYELLAYRTREFWGTARKVNKESVFAVDHLTYPFTYDNVDLSKGSVLITPHGKDPVLVGIRGIDKNKVIWAFENITFEEPIDFFQIYKTNQNTDDHLRFKKIAELKPLDSAIVRGKVIKKYWEKGRHVFFEISDDTGKLRVAAFEPTKGFRKYVRMLIEGDEIIAAGGVKEFNGVLTLNLEKFYPIKLTEKITYEKPKCPKCKGTMKSKGEYLKCKKCGYKMKKVLIPKRIPRDLKRKIYEVPPDARKHLSRPLVLPMAENKILDVLKLKR
What is the function of this protein?
ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
What are the official names of this protein?
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS, tRNA(Ile2)-agm2C synthetase, tRNA(Ile2) agmatidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the TiaS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_NEIMA
Sequence: MAEITAKMVADLRAATGLGMMECKKALVEAEGNFDKAEEILRIKSGAKAGKLAGRTAAEGVLAYAINGNVGALVEVNCETDFVAKDAGFVEFANFVAKTAAEKKPASVEELSELVEAERKAIIAKLGENMSVRRFQVIDTANQLVAYIHGALATEGVLVEYKGSEDVARKIGMHIVAAKPQCVSEAEVDAETVEKERHIYTEQAIASGKPADIAAKMVEGRIRKFLAEITLNGQAFVMNPDQTVAQFSKENGTEVISFVRYKVGDGIEKKAVDYAAEVAAAAKV
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CESS1_CONMO
Sequence: MQMGRPTLLPCLLLLLVLSTQACFIRNCPEGGKRDVHMIQPTKPCMNCSFGQCVGPRVCCGAGRCEIGSTEADRCEEENEDPVPCKVLGQHCVLNNPGNVNGNCVDGGIGICCVDDTCAIHRRCD
What is the function of this protein?
Targets vasopressin-oxytocin related receptors.
What are the official names of this protein?
Conopressin-conophysin, isoform 1.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: H4_CHICK
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: BOP1_LEIMA
Sequence: MTSPKGKPSPKRSAPAPATAALTPCAEERTEGATSSASASASSHISSSFDSPRDDTVVLTGYTAESEHSAHGYERLHDIILQGSDTDADSEDGRANEDDVILFPHAEELSNAAAGVGGDDDNGRVVRLGTTQHLDESDSSEDEPTLNRVGDIPLEWYKDEDHIGYDIEGKKLMKKERSALERLLEATDDPNAMRTIYDALHDEKKTLSNADLQLIFNLQRNRTTNPNYDMYSEVQEDTVVFDPLNHPLARSGGPSKKAFVPALHDMKVIAKMVRRLRKEEAERRLRPAKEEKEEEDQLLWDDSHVEMDTHTHFKYFNRIPKPKLPPPGTFESYRPPPEYLPSERAKQRQARLRTIDRKEHFLPQSFDALRHVPFYHHTIQDRYQRCLDLAFFPRAQRTRLVVDPDKLLPELPDPKDLRPYPEKLSFHYKGHTATVRSVSVSPNGQYLATGCDDHLVRVFEVQTGRLMKRYDMGAPVQQVEFCPSTSLNILAVAVEYSLVFIVPTFAAHTLVNDHTIRFLRAPGLSAGQREAAHALGAVDTLGGRAVTQTALDADETAHEATADLHDIEEREKRAEFVDASAKERNAGIVVKIAMHAKVKKFCFHIKGDYLCALCPKDHVKYRQTIMLQLSKRKVFCPFRKFSEVVTDCRFHPREPIFFLATTNSVRCYNLMAHRLQRRFKASGGVTTCLSIHPEGDNFLVGDTTSHTSWFDMDFSDKPYKRMRSHKGVVNALAFHPKTNAYPLFATGASDGQVHVFHGMVYDDYNKNALVVPVKILKHQRPVYAVAWHPTLAWLFTSTEDGVVTAWTE
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: PANB_PHEZH
Sequence: MSSHREEKVRRIAAPDIAARKGGTPIVCLTAYTAPVAELLDEHCDLLLVGDSVGMVVHGLPNTVGVTLDMMILHGQAVMRGSRRAMVVVDMPFGSYEGAPETAYDNAARLMKETGAQAVKVESGPTVIDTIQYLVKRGIPVMGHVGLRPQAVLVDGGFKAKGKAGEERRRILEEARATADAGAFAVVVEGVAEGLAREITEAIEVPTIGIGASAGCDGQILVTDDMLGLFDWTPKFVRRYGDLRGEIGKAVAAYAEDVRARRFPGPAEIYFAKAG
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_COROL
Sequence: VGFKAGVKEYKLTYYTPSYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEETQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCTEALYKAQSETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGLFFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEIWKEIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TIG_PSET1
Sequence: MQVSVETTQGLERRLTITVPAENVENEVKKRLQQLSKTQRIDGFRAGKVPASVINKRFGPAVRQEVAGEVMQRNFYEAIVSEKINPAGAPTFAPKALEAGKDLEFSATFEVYPEVEVQGLDKITVEKPAVTVTDEDLANMLETLRKQHADWAEVDTAAGENDRVTVDFVGTIDGEVFEGGKAEDFPLELGQGRMIPGFEDNIVGKKAGEEAIADVTFPDDYHAENLKGKAAQFTITVKKVEAQELPELSEEFATKFGVTEGGVDALKVEVKKNMTRELDQAVKANVKDQAIKGLLANNEIEVPKALVDQEVDALRQQAAQRFGGDAQNMPELPAELFHEQAVTRVKTGLLLGEVIKANEIKVDDAKVEALIATVASAYEDPTEVVEYYKANDQLMQQMRNVAMEEQAVEAILAKATVTDVETAFDDIMNPQQGA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: Y5948_SOLUE
Sequence: MSGHSKWATIKHKKAATDAKRGRAFTRLIKEITIAARNGGDPDGNPRLRSAILAAKNVSMPSDNIKKAIMRGTGELEGGQIEEVMFEGYGPGGAAVLVNVATDNRNRTVSEIRHAFSKNGGNMGEQGSVAWMFERRSQIFVPIEKATEDQLMGIVLDAGGDDLRNDGDQWEVLSDPASHDSVLKALESNGIPVVDPTIAWVPKNLMKLEGKNASGMLRLTEVLEDHDDVQSVYSNFDIDEKELEALSQ
What are the official names of this protein?
Probable transcriptional regulatory protein Acid_5948.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YE148_YEAST
Sequence: MFYNKMFIHSISGGSSLLSASEVFASAFFSKASSLSSLNLCSRSSDNSFSYFLCVLVSTFLNSLVIIESERDPEPLVGLPTEEGELGSQVTGELAGDDMPKLCLLEFSLLLAFSSSLFSCSNSCNFFSVLLKFEWLFNNLSCNSLLVRVSFSISCTYSARSFSNCLVKKLCASCKSLNAVSSSSNFLEESSS
What are the official names of this protein?
Putative uncharacterized membrane protein YER148W-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENGB_AZOSB
Sequence: MPLFRNAQFEISIAKPSGLPPPNGAEIAFAGRSNAGKSSAINTLAGHVRLAYVSKTPGRTQLINFFRLNCGALLVDLPGYGYAAVPEKIRRQWQGLIETYLRTRESLIGLVLMMDSRHPMTDLDRQMIDWFAPSGKPIHVLLTKSDKLSRGPANATLLAVRAELTARYGDQVSVQLFSSLKKTGVEEVEKVVAGWLVPAAAEGEAPAGA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: COAD_PARMW
Sequence: MRALYPGSFDPLTNGHMDLIERAVALFGQVTVAVLSNPNKKPAFSVDQRIGQIQCATRHLNGIDVVSFDGLTVHCAVTHQADLILRGLRAMSDFEYELQIAHTNRSLAEDLETVFLATSTRHSFLSSSVVKEVARFGGPVDHMVPKEVAKDLNRLFNSTFPPR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR18_DRIGR
Sequence: MDKSKRPFRKSKRSFRRRLPPIGSGDRIDYRNMSLISRFISEQGKILSRRVNRLTLKQQRLITIAIKQARILSSLPFLNNEKQFERTESTPRTAGPKTRNK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL19E_NATPD
Sequence: MTDLKAQKRLAADILDVGENRVRFDPDAQAEIADAITREDIRELIEDGTIEAKTAKGNSRGRARKRQQKRAYGHKKGHGSRKGRSGGRQNEKEDWQSRIRAQRRELRELRDAGDISREQYRELYDMASGGEFDSVADLNRYIDDKHGEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L19e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
Protein: CSPA_BACCE
Sequence: MTVTGQVKWFNNEKGFGFIEVPGENDVFVHFSAIETDGFKSLEEGQKVSFEIEDGNRGPQAKNVIKL
What is the function of this protein?
Can bind to ATTGG and CCAAT motifs (Y-box motifs) of single-stranded oligonucleotides.
What are the official names of this protein?
Major cold shock protein CspA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSC6_STRGC
Sequence: MTRLQDDFYDAINGEWAKTAVIPDDKPVTGGFMDLAEEIEDLMLSTTDKWLAGDGVPEDAILQNFVAYHRLAADYDKREAAGTEPARAYIDEIRNLASFEEYASKIADFELAGKPTYFPFGVAPDFMDARINVLWADGPGTILPDTTYYAEDHPQKADLLAKWRKAQEDLLAKFDFTEEEIKDLLDKVLDLDAVFAQYVLSNEESSEYAKLYHPYKWDDFKALVPELPLTDIFTKLIGQEPDQVIVPEERFWKAAKDIYTAANWDKLHALLILSAVRNTTPYLTDDIRVLAGAYQRALSGTPQAQDKKKAAYYLAQGPFNQAIGLWYAGQKFSPEAKADVEQKVVTMIEVYKNRLAQNDWLTPETRDKAIVKLNVIKPYIGYPDELPERYSRKIVDENLTLFENAQKLSLIDIAYSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFPAAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLNNWWTEHDYQAFTERTQKVIDQFEGQDSYGAKVNGKLTVSENVADLGGIAAALEAAKKEADFSAEEF
What are the official names of this protein?
Putative zinc metalloproteinase in scaA 5'region, ORF6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
Protein: HSLV_STRMK
Sequence: MDPSQNPNVFHATTIVCVRRGEHVAIAGDGQVTLGHTVMKGNARKVRRLGRDGQVLAGFAGAAADAFTLFELFEAKLEKHGQLQRAAVELAKDWRTERRLGKLEALLAVADKETSLIISGTGDVIEPEDGIIAIGSGGSYALSAARALMAHTELDARTIASEAIGIAGDICIYTNRNVVVEEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM11_PICST
Sequence: MSVEAASNSSDQSGLKPFLAKYNFKLGEASDEYIARRKRQMVLFMSSAALTIFASRFAYKSTISRQYIPTLFQGNHAPPLSYNFATDAAVAVGTGTLLCGSVSSMVIFGSCWILDVSNFKEFGWKMKSMMGGYEKERELSKLPMDEESAYIQDGLNDILEGKYDFDEDGTEEGK
What are the official names of this protein?
Altered inheritance of mitochondria protein 11.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL27_LEPBJ
Sequence: MAHKKGGGSSKNGRDSNSQRLGVKRFGGESVLAGNILVRQRGTKFRPGNNVGLGKDHTLFALVTGKVKFEMVTKLKMQVSVYPE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: DHB12_BOVIN
Sequence: METALPAAGFLYWVGASTVAYLALRISCWFFTALRVWGLGHEAGVGPWLGEWAVVTGGTDGIGKSYAEELAKRGMKIVLISRSQDKLDQVSSEISEKFKVETKTIAVDFTSEDIYDKIKASLAGLNIGVLVNNVGMSYEYPEYFLDVPDLDNTIKKLITVNALSVCKMTRLVLPGMVERSKGAILNISSASGMYPVPLLTIYSATKAFVDFFSQCLHEEYKSKGVIVQSVLPYYVATKLAKIKRPTWDKPSPETFVKSAMKTIGVQSRTNGYPIHSLVASVSASLPSWLYFKIAMYSGNSIRVRYLKKMKMN
What is the function of this protein?
Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation.  Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 17-beta-hydroxysteroid dehydrogenase 12, 17-beta-HSD 12, 3-ketoacyl-CoA reductase, KAR, Estradiol 17-beta-dehydrogenase 12.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TIG_PSYWF
Sequence: MAKDLQVTTSKVNDNQTQLTVKVPVEQIQNKVEGRIRNVAKTAKIDGFRKGKVPVSHIRAQYGAGIQQEVINDVIRDTVFEAIKAEDVRAVGMPNIDDVKLEDEFLVYQATVEIFPEIKVEGMSDIEVERHTATITDEDVDTMIENLRKQRQEFAEKEGAADEGDQVTFDFEGSIDGEKFEGGSAEDFKLVLGSGQMIPGFEDGIKGLAAGEEKTIDVTFPEDYQAENLAGKEAQFKINVKKVEEAKLPEINDEFLELFGVKEGGVEQLKTDVRKNMTREIKNAARNQVKQAAFDALLEKNEFDVPSAMVDQEVDRQRNLMMQRFAQQFGGNANSIDKDMLPRELFEEQAIRAARLGVLVSRVIEENDLKVDQERVETFIKETAENYEDPQEVIEYYTNDAQQRANIESVVLEDQVVDFLLEQGKVTDKEVGYQELLASQQQGMM
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL11_HCMVM
Sequence: MQTYSTPLTLIIVTSLFLFTTQGSSSNAVEPTKKPLKLANYRATCEDRTRTLVTRLNTSHHSVVWQRYDIYSRYMRRMPPLCIITDAYKETTHQGGATFTCTRQNLTLYNLTVKDTGVYLLQDQYTGDVEAFYLIIHPRSFCRALETRRCFYPGPGRVVVTDSQEADRAIISDLKRQWSGLSLHCAWVSGLMIFVGALVICFLRSQRIGEQDAEQLRTDLDTEPLLLTVDGDLE
What are the official names of this protein?
Membrane glycoprotein RL11.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: ISPH_CORGB
Sequence: MSSPVISPETKTGKKILLAAPRGYCAGVDRAVETVERALEEYGAPIYVRKEIVHNRYVVDTLAEKGAIFVNEASEAPEGANMVFSAHGVSPMVHEEAAAKNIKAIDAACPLVTKVHKEVQRFDKQGFHILFIGHEGHEEVEGTMGHSVEKTHLVDGVAGIATLPEFLNDEPNLIWLSQTTLSVDETMEIVRELKVKFPQLQDPPSDDICYATQNRQVAVKAIAERCELMIVVGSRNSSNSVRLVEVAKQNGADNAYLVDYAREIDPAWFEGVETIGISSGASVPEILVQGVIERLAEFGYDDVEEVTSAAEKIVFALPRVLRHKN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RBM44_BOVIN
Sequence: MQATAVVETASNKGYNNNGRNIQKDEPSHHKKENLLSPNGCKEAKLTFLNDYYDSLALEKRANDKEISNIDKIDLLEPSFTMSPDTNIESAHSQSSEFEDNIDYAFLNETYTIHYSESKLKSESLIHLNSELDSEMQKREEVFFDILEHQGDKITDLERIYKISYDDYKKTAEDVQKPDIDEDSQQEYHSAEEQECINNHLSFDQAKTLDIPNLEVLGLRNSGCEVKCVSNLEDSHVKLESNSSISLDSVDVYGQEDSPSVSKLQNSVTLRAFHEPKYEKCKEQGTSLMLHTVLDEIILRSSHLEHKESESKGFLNPQKALKTKIYTHKVNPQLTESKDSIGNVIVEDKMLQHLDNPGTLPQDKHLETLLQPCKDCQTSSVFDDSVISASGYSHYESLQSTPNPALDVSITLPRSAIRGNQAVEESGSLKVANGNTISKAHFHNMEGPCPKSETDAAGCTVTVDQTVDVSTDFRACFTASRATSARSSVVSTSSNTEITMMNKKRPSEWQSEKQRSVACNTDWSYIQDTEDPQMAMTKGPTGKSLSVDNLKPNGNVLNKDSLELKTFEFTDLKKHSESMLQIQVEKNLPSKCCQQIMQRAIQAESHLLNVHYQLCHRHCSDIYRLVMEDREGLNRNLSSNSTRKELGSALLSVLGDLKVRYMNLKEKINKGIPLEELPPLSIESRLLSAFSTFASRLMKEESHIFSGADSELDNQSTRDVGSSSLKKTLSQTSLLLDNGHPKQDKSPEEGGLKNGDINVDLSQLKLDDKDCKNYREVSEDWFDAKENLTGADFSGIQENQIEQDKGDPKFTLAEIKNVEPLRKDKGYLMHVGGLCPSVSEADLRSYFQKYEISDISIYDSSPNYRYASLAFKKNSDAKMAVKEMNGIEIKGKSVNVRLVKTPGEYTPLSSKNGNKVSFSNLEKSTSKEMSSPSSVSRLPRTRPRQPGSEQDSEFFPFDQKGVKKNCKQIESTKLLPDTPIQFIPPKTLNLRSFTKIIKRLAELHPEVSRHRDHIIDALQEVRVNHKGFLNGLSINTIVEMTSSVLENSASS
What is the function of this protein?
Component of intercellular bridges during meiosis.  Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells.  Not required for fertility (By similarity).
What are the official names of this protein?
RNA-binding protein 44, RNA-binding motif protein 44.
What are the subcellular locations of this protein?
Cytoplasm. Note=Detected in the intercellular bridges.
Protein: MGSA_SALTI
Sequence: MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYATGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: VP7_ROTB2
Sequence: MLLFIILSVGVDAISYIQNDRSNDLCIIYEMTSFGASFNNANDSLVKLHRHMGLKYEICKIESNANALTQMQKCNCLYDDTPQIVVFTNFRKSSLKTLIGTENKCELLPQTTIYTPTVDIESEYFIYGNDVKICYLDKNLLGIGCDATDTTSWLDLDAGLPTNHAIDIPEITSDGFKLFAKYGDSFLCQRLMDEPKKQIQFYAEVDNVPSNDVIESSRSWASVWKVVKTVLHFTYHILDLFYGNKRATARMIEHSPLG
What is the function of this protein?
Outer capsid protein involved in attachment and possibly entry into the host epithelial cell.  It is subsequently lost, together with VP4, following virus entry into the host cell.  The outer layer contains 780 copies of VP7, grouped as 260 trimers.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors (By similarity).
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host rough endoplasmic reticulum membrane; Single-pass membrane protein; Lumenal side. Note=Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles (By similarity).
Protein: RA51A_XENLA
Sequence: MAMQAHYEAEATEEEHFGPQAISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELLNIKGISEAKAEKILAEAAKLVPMGFTTATEFHQRRSEIIQISTGSKELDKLLQGGVETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMAESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
What is the function of this protein?
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR).  Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange.  Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template.  Recruited to resolve stalled replication forks during replication stress.  Also involved in interstrand cross-link repair.
What are the official names of this protein?
DNA repair protein RAD51 homolog A, xRAD51.1.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=Accumulated at sites of DNA damage. Recruited to stalled replication forks during replication stress.