PharMolix/UniProtQA huggingface dataset:
Protein: TRPB_ECOLI
Sequence: MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILKARGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RBSD_GEOKA
Sequence: MKKSGILNKELNTLLASLGHTDTIVIADCGLPIPNEQARIDLSLVKGFPPFLSVLDAVVDELEIEAIVLAEEIKDQNPDLYESIRARMGGVPVQFVPHEQFKAMTKQAKAVIRTGEATPYANIILRSGVSFSSKDF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRP_XENLA
Sequence: MERFALWFIFLAGSLAQEDLVGNVFLFPKPSVTTYAILKPEVEKPLKNLTVCLRSYTTLTRFHSLLSLATSNPLQDNAFLLFSKPPNQCSIYINQEENVFKVDPTAVEWKHTCVSWDSVSGVVELWIDGKLYPRTVSKKASSIGFPSSIIQGQEQDSFGGGFNIDQSFVGEISDVHMWDYVLTPDHIQKVLFANMDFNGNIISWRSLQYELRGQATTQPKRQCKTLEHHYGLFAKCYK
What is the function of this protein?
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine.
What are the official names of this protein?
C-reactive protein, CRP.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRCB_CAMHC
Sequence: MFYTILCVGTGGFVGAILRFLFYFGFAQFFSQKYIFIATICVNIIGSFIIGFVLNIATTYAINYNFKNFLVTGLLGALTTFSTFTYENAVFLNHGEISKFFLNITMSIILCLIFCFLGIYTAKIIH
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBW_ARATH
Sequence: MASFTASASTVSAARPALLLKPTVAISAPVLGLPPMGKKKGGVRCSMETKQGNVSVMGAGVSAAATAALTAVMSNPAMALVDERMSTEGTGLPFGLSNNLLGWILFGVFGLIWTFFFVYTSSLEEDEESGLSL
What is the function of this protein?
Stabilizes dimeric photosystem II (PSII).  In its absence no dimeric PSII accumulates and there is a reduction of monomeric PSII.
What are the official names of this protein?
Photosystem II reaction center W protein, chloroplastic, PSII 6.1 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the psbW family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein. Note=The N-terminus is found within the thylakoid lumen (By similarity).
Protein: AKND1_HUMAN
Sequence: MDEADFSEHTTYKQEDLPYDGDLSQIKIGNDYSFTSKKDGLEVLNQIIFIADDPQEKAMHSETCGNTAVTIPLGKITENAANKKDEKEKQCTAALHIPANEGDASKSSISDILLHHLSKEPFLRGQGIDCETLPEISNADSFEEEAIIKSIISCYNKNSWPKEQTPELTDQLNPKRDGENSNKPGSATTTEENTSDLEGPVAAGDSSHQENVNVLTKTKGPGDKQKSYQGQSPQKQQTEKANSGNTFKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESKYTSAPSLPVSSPVTLDDLASTFSSLSNEIPKEHPGHPSGPRGSGGSEVTGTPQGGPQEAPNEELCELAPQTYLNGHYGDAAAQNKPDQVAMRLSSNSGEDPNGTPRRQDCAEMTAPSPSCAFCRRLLEWKQNVEKKGHGRINCGRFSIVLHEKAPHSDSTPNSDTGHSFCSDSGTEMQSNKCQDCGTKIPTSRRACRKEPTKEFHYRYNTPGQNYSNHSKRGAFVQPHSLDESKNSSPSFLKPKRICSQRVNSKSFKGEHEPTPGKKKLQAFMTYSSDPATPSPHFYSCRISGSKSLCDFDSTEEIKSEILNSALDHALRTATILKETTDQMIKTIAEDLAKAQRWRNRLKY
What are the official names of this protein?
Protein AKNAD1.
What is the protein family that this protein belongs to?
Belongs to the AKNA family.
Protein: AGRA3_HUMAN
Sequence: MEPPGRRRGRAQPPLLLPLSLLALLALLGGGGGGGAAALPAGCKHDGRPRGAGRAAGAAEGKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISSIDPGAFWGLSSLKRLDLTNNRIGCLNADIFRGLTNLVRLNLSGNLFSSLSQGTFDYLASLRSLEFQTEYLLCDCNILWMHRWVKEKNITVRDTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLPFQCMASYIDQDMQVLWYQDGRIVETDESQGIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKGDFRWPRTLAGITAYLQCTRNTHGSGIYPGNPQDERKAWRRCDRGGFWADDDYSRCQYANDVTRVLYMFNQMPLNLTNAVATARQLLAYTVEAANFSDKMDVIFVAEMIEKFGRFTKEEKSKELGDVMVDIASNIMLADERVLWLAQREAKACSRIVQCLQRIATYRLAGGAHVYSTYSPNIALEAYVIKSTGFTGMTCTVFQKVAASDRTGLSDYGRRDPEGNLDKQLSFKCNVSNTFSSLALKNTIVEASIQLPPSLFSPKQKRELRPTDDSLYKLQLIAFRNGKLFPATGNSTNLADDGKRRTVVTPVILTKIDGVNVDTHHIPVNVTLRRIAHGADAVAARWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMDLTGSELYTQAASLLHPVVYTTAIILLLCLLAVIVSYIYHHSLIRISLKSWHMLVNLCFHIFLTCVVFVGGITQTRNASICQAVGIILHYSTLATVLWVGVTARNIYKQVTKKAKRCQDPDEPPPPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSRPNAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPTEEQQRLAANENGEINHQDSMSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYYPLDLVFSFVFGATSLSFSAFFVVHHCVNREDVRLAWIMTCCPGRSSYSVQVNVQPPNSNGTNGEAPKCPNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQCHANSLPLNSTPQLDNSLTEHSMDNDIKMHVAPLEVQFRTNVHSSRHHKNRSKGHRASRLTVLREYAYDVPTSVEGSVQNGLPKSRLGNNEGHSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSSRNFEKPVSTTSKKDALRKPAVVELENQQKSYGLNLAIQNGPIKSNGQEGPLLGTDSTGNVRTGLWKHETTV
What is the function of this protein?
Orphan receptor that may have a role in planar cell polarity pathway.
What are the official names of this protein?
Adhesion G protein-coupled receptor A3, G-protein coupled receptor 125.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: RIMP_CORGL
Sequence: MAFPTTEILSALIEPLAASHKFDLEGLKVTKAGPKSAVAIKVDSDSRPDLDQLEVFSQEIGELFDAAEQRGELNFGAGYTLEVSTPGVDNPLTLPRHWRRNRGRLVALDQDGKKRVARIGALNDAETHVVLIERNKKLLEVTTLELAHSPRAVVEIEFAKPAQDETALAESTFDEATA
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_SHIDS
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFNALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVVDNGDVMFDVPTDPTYGVLSRQDLDQLLAGARVDVVDDKRNTMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_ANAD2
Sequence: MTLRYLTAGESHGPALVAIAEGFPAGLAVDFEAVDRDLRRRQKGYGRGGRMKIETDAAQFLAGLRGGLTTGAPIALAVWNKDHENWKDLVSPYARGGKKFTQVRPGHADLAGALKYGLDDARDVLERASARSTAVTVALGALAKALLSTLGVEVCSRVVAIGPREIRPDAPPTPAQRDAIEASDLHVDDEALAAEWRALIDAEKARGGSIGGAFDVYATGLPIGVGSHVHPDRRLDARLAGALCGVQAIRAVEIGDGTQVGRPGYEFHDAIHHDPARGFWRDTNRAGGLEGGMTDGMPLRVRAYMKPIPTMLHPLATVDLATRAATQARYERSDVCAVPAAAVVGEAVVAWELANALLEKFGGDAVEDVRRAVEAYAARIR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RUTC_PSEU2
Sequence: MTKKAIIPAGTSKPIAPFVPGSMADGVLYVSGTLPFDKDNNVVHVGDATAQTRHVLEAIKSVVETAGGTLDDVTFNMIMIRDWADYAKVNEVYAEYFAGEKPARYCIQCGLVKPEALIEIASIAHIG
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: GLPK_BURVG
Sequence: MQDQYILALDQGTTSSRAMLFDRQGNIVSIAQKEFEQIYPQPGWVEHDPQEIWSTQAGVAAEAVTRTGLNGTSIAAIGITNQRETTIVWDRETGQPVYNAIVWQDRRTADFCDSLKQQGLEAKVRAKTGLPIDSYFSATKIRWILDNVPGARDKARQGKLAFGTVDSWLVWNFTKHELHVTDVTNASRTMLFNIHTREWDSELLELLDIPRSMLPEVKASSEIYGHTKTTVFASKIPLAGIAGDQHAALFGQMCTTSGMVKNTYGTGCFLMMNTGDKPIESRNNLVTTIAWQIGDDVQYALEGSIFIAGAVVQWLRDGMGIIKTAAEIEALAARVPHTDGVYLVPAFAGLGAPHWNARARGSVFGVTRGTTSAHLARAALDAIAYQSLDVLAAMEADSGISIGELRVDGGASANNLLMQFQADLLGVDAVRPQITETTALGAAYLAGLAIGYWKNLDEVRSQWQLDRRFSPSMPKEQVKQCMAGWQRAVRAAKAWADDTQ
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RPC7L_HUMAN
Sequence: MASRGGGRGRGRGQLTFNVEAVGIGKGDALPPPTLQPSPLFPPLEFRPVPLPSGEEGEYVLALKQELRGAMRQLPYFIRPAVPKRDVERYSDKYQMSGPIDNAIDWNPDWRRLPRELKIRVRKLQKERITILLPKRPPKTTEDKEETIQKLETLEKKEEEVTSEEDEEKEEEEEKEEEEEEEYDEEEHEEETDYIMSYFDNGEDFGGDSDDNMDEAIY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC7-like, RNA polymerase III subunit C7-like, DNA-directed RNA polymerase III subunit G-like, RNA polymerase III 32 kDa beta subunit, RPC32-beta.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSRF_PHOLL
Sequence: MADLDDIKDGKDFGIDIPQKNSLFELKGCGALDWGMQSRLSRIFNPKTNRTVMLAFDHGYFQGPTTGLERIDINIAPLFPHTDVLMCTRGILRSQVPPATNKPVVLRASGANSILTELSNEAVAVAMEDALRLNVCAVAAQVYIGSEYEHQSIKNIIKLVDQGMRYGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGAQIIKTYYVDTGFERIASGCPVPIVIAGGKKLPEKEALEMCYQAIDQGAAGVDMGRNIFQSEAPVAMLKAVQAVVHQNENASKAYELFLSEKQ
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
What are the official names of this protein?
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RH22_ORYSJ
Sequence: MALHHLRHAPLALRLARLPRLAPSPPPPAARLLLLLAPSQHPAPPWRLLSRPRALATAAAEADDAGAGGNGDGDGFFSEESTSWESLGVSDRLASALHGAGLARPSLVQAACIPHVLTTNDVIVAAETGSGKTHGYLVPLIEKLCSKSISAEDGNSQDVTSGSPNIALVLCPNVMLCEQVVRMANSLVDESGEPLKSAAAVCGPKGWPTVRPDILVATPAALLNYLFDYDPEKRRRERFLRNVKFIVFDEADMLLCGSFENQVIRLIHMLRFDEKLLSRMEDSGKEISLGDTNEYREDSDSQSAELSADDEENEDGLVQHRPVNVENAHIGAHKKDWRRVRKVYRRSKQYVFVAATLPQSGKKTAGGVLKRMFPNAVWVSGAYLHRHNPRLERRWIEVTADTQVSALLDAVKYGLKNEVHDTKLGPNRTMVFTNTVDAANSVSDILQRVGVPCILYHRDSSLEERAKNLQSFRENGGVLVCTDAAARGLDVPNVSHVIQAEFAACAVDFLHRVGRTARAGQSGIVTSLYTEANRDLVRAVRQAEELAQPVEKAFSRKRSFRNKLKKQALHKSTALLS
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 22.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: SODM_STRIN
Sequence: QFDQETMTLHHDKHHATYVANANAALEKHPEIGENLEELLANVESIPADIRQALINNGGGHLNHALFWELLSPEKTEVTKEVASAIDQAFGSFDAFKEQFAAAATGRFGSGWAWLVVTKEGSLEITSTANQDTPISEGKKPILAL
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: SERC_XANCB
Sequence: MTRAFNFSAGPATLPESVLRQAQEEMVEWNGVGASIVEISHRSADFMAVAAAAEADLRTLLSIPDDYAVLFTSGGATTIQALLPLNFAAPGQAVDYVVSGHWGKTAIKQATPYVDVRVAADGQPGGYVDIPPVASWTLSPHAAYVHITANETIHGVEFRDTPDVGTLPLFADFSSSIASEPLDIRRYGLIYAGAQKNLGPVGISVVIVRRELLERAGQPRADIFNYASHVARDSMLNTPPTWNWYLLGLTVKWMLEQGGVAAFAQCNAEKAALVYGAIDGSGGFYRNQVMPTVRSRMNIPFFLGDEQLDALFVSESKAAGLLALKGHKAVGGIRASLYNAMPVAGAQALVAFMHDFQQRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRA_DICDI
Sequence: MKNDHINYQQNLSQSPILNSNKNQTQQNQQQQQQQQQQNPQQQQQFQHQQVPQLSPQQIPFSEPLKNNLTLQHQQQQQQHQQLAGGQHGSLLRKSYSSRFHEKPQGELTKIANFQDVSPEERPSLFLLKLKQCCYVYDFSDNTYMVSKGVKQEALLQCVNFLSTNDQPLHESIYKMVFEMVAVNLFRPLPPRINPYGVMYDPEEDEPILEAAWPHIQVVYEVLLRFIDSPTFNTHIAKNYVDDRFVLQMLDLFDSEDPRERDYLKTTLHRIYGKFLGLRGFIRTAIRNLFCTFVYESHQHNGISEILEVLGSIINGFLVPLKDEHKQFLIKVLIPLHKPKSYSVYCSHLGYCMSQFIEKEPSLAEPIFKSILRLWPCGNSQKEVLFLSEMEDLLGLVSDEQFAKFRNQFFRQMTKCFQSEHFQVAERALYLFSNENIVLLIASKNNFTLALETFYKPLHENSISHWNRSIRNLSISSLKLFMEIDMDLFNKISEKYKESKKKQQQIQQREKFKQNAPETQKSKQINQNNNNNNNNINNNNNNNNNNNGSTETKADKPSMIRRKSLLPVDPSTIAALSSHRSLEDIMSTNSNSGNDDDDENNHTNHDSEIENEVKEDFRVPVNNRYTFT
What is the function of this protein?
Involved in developmental cell fate decision.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A regulatory subunit psrA, Protein PPP2R5A/B56 homolog, Protein phosphatase 2A regulatory B subunit, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit, protein phosphatase 2A B56 regulatory subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CARA_HELHP
Sequence: MSILKEAYLYFANGLFFKAQSFGSDGTFVGEVVFNTSMSGYQEVITDPSYSGQFIVFSMPEIGIVGVNNQDSESPRAACTGVILSSYNDFVSNFRSEQSLSTYLKEHNIMGICGVDTRNLIKMLTTQGAMMMIASTQITQESELKASLSRTPPIQDINFIKEVSTKTSYVHTDSTFDFTHFAYGTSPNFKAKVVAIDFGAKRNILNELVAVGLEVEVIPHSFSAAEILSRFKAGEIQGVFLSNGPGDPLVLHNEIEQIKQLIQSDIPIFGICLGHQLLSIAHGFPTYKLKFGHHGSNHPIKNLQSGAVEITAQNHNYCVPESIAQIATITHRNLFDNTIEGVRYKDKPIFSVQHHPEASPGPREARILFEEFAKLCCK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: IML2_YARLI
Sequence: MLKALGLGKRGGDMPTKPLNNSTVSLAIMDDALRVEEAFIAMDMVMDDRSKEALKLIQKDEPGSSGKSVAREQSAFYKLVIGVIYFIEATLGFEPESIRRASEALAEAEAAAVRQKRNVSNNGAHVSYSKYPPGTEYRVAFAEAELMGAITLFLSESYLESVKALYKLRKAYQTLDEISKSIRESKKPAKSSDHKSTLDSLSLAVSDDQEMASLVEKFQKTRLNRLNESNNATPVASSAASMNTTTSSATALHQGSETIEEFIESGVDLCFGILQLVISIIPPTLGKILSVVGFRGSRDGGLSLLWEATNYRNIHGALALLVLLQFYDGPTQFSDLILPGTEEDLIQQGKYDINTADDTEITLTATITGGSGHSKKVHTLPKNPRRRMHKLLLAARGYYPHSALWMLQQGRMEASQCHLEKAVDIMDADIGPIEMKQVEALMLFDKTMFMLFLNRYEQSATNFIRLIDINAWSHAWYTYVAATCSIEIYRENLRAGNAEAAKKAKDTATRLLTEAPGLIGKKKLMAKTMPMDVFLSRKISQMQQLSKQHNIDLVDAAGVSPVQEVVYFWNGYGKMPEYALEKVFSEVLAYSAAPLAPSHIPEQDNEKTVRHLLQAVALRNMGKVEEGYKILNDNVISQIITESNNKYHYNKTVTHKDPWMPPSALYERAMFEWVMHGPKGTETVREWLHLAEKWSDDYELSTRVGMKIKSAFERLDGGALA
What is the function of this protein?
Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins.  Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
What are the official names of this protein?
Inclusion body clearance protein IML2.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized exclusively in cytoplasmic inclusion bodies under protein folding stress conditions.
Protein: CIDA_BACCQ
Sequence: MKWWKLSGQILLLFCFAWTGEWIAKQAHLPVPGSIIGIFLLLISLKFNLVKKEWIQDGADFLLKELILFFIPSAVAVIRYKDTLSQYGIDLILIIMISTLCVTLVTGLLTELLLKRKGSVQ
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: REPA_MISV9
Sequence: MRAPASSAASNRPGPSNHPTPRWNSKQFFLTYPHCNLTPSELMKELFSRLTEKIPGYIKVSQEFHKDGDPHLHVLIQLNTKLCTRNPKFFDVQGFHPNIQPVRDAEKVFGYISKTNGDSDEMGELQLRIKKPEKPTRDQRMAMIIASSTNRNEYLSMVRKEFPFDWAIRLQQFEYSAAALFTEPPPVYQSPFPNEQIVCPPELVDIIDQEWNQVTTD
What is the function of this protein?
Implicated in enhancement of V-sense gene expression.  Acts a an inhibitor of C-sense gene transcription (By similarity).
What are the official names of this protein?
Replication-associated protein A, RepA.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: CCNO_HUMAN
Sequence: MVTPCPTSPSSPAARAGRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDLFESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQTFRDYGQSCYAFRKAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGAPTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLADYAFTSYSPSLLAICCLALADRMLRVSRPVDLRLGDHPEAALEDCMGKLQLLVAINSTSLTHMLPVQICEKCSLPPSSK
What is the function of this protein?
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation.  Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking.
What are the official names of this protein?
Cyclin-O.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Localizes to the apical part of cytoplasm.
Protein: MAD1_CANAL
Sequence: MSTGSSPFVDHKSNNSTISINNNSSILNESSISKAYVSKLEFQLDTIKTENRILQQEKDQITSDYRKIIDEKNQELENLKLNFKYVYDEKNQLESKLTNQEQVSTNNINQLSDEIQTYKRENLKLTKDYNSLLDKFNKLNRKNQQIMHDLNKEIEVNDKLHQELKIKEKTNQELQKASDTAINELEQYSKILDKKNGSDNLLYKNLTTKSNNLQNINHQLQNKIDQLLQNKTSNELLKQQNQSLLHKLQNLENIESKYLQLEIEKLQLETKYNDLFKALDTAIASSNEYKDNENTDDTIHTSKVKSFIEYCNNLQAKNLTLQEKYDSKIIQVKELTKELEDHAREIETDFLPTITDLESKLKVYADQNTKLERTKSLREKEITFLRNSLKQMEQIHANQQHKQQEQEKEENTENKSISQYMTNLEKLVDEYKTKIDELEKKNLEYNKSSIITNEKTPSNKRQRLESNYTFKTQAIELEKENIEISSKLKQAESTIEQLKFKISELDKVETRKEQYRILQLKNNLISQDQFIKQTTLIALRKENEELINKYIKNLPIEEQIPKGVFQRQEDDKQRLQAQIDHLTKRSTRLREVFTKKSKDIITVIAKYFGFIIEFLPNPINPTDLFSRIKLRSRYIPSEEDCYLIIDVENRGLKAHGNFQFKQICEELAQYWVNENNQFPCLLSAVNLKLYEIYASK
What is the function of this protein?
Central component of the spindle assembly checkpoint which is a feedback control that prevents cells with incompletely assembled spindles from leaving mitosis.
What are the official names of this protein?
Spindle assembly checkpoint component MAD1.
What is the protein family that this protein belongs to?
Belongs to the MAD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGSC2_DROSI
Sequence: MANKALILLAVLFCAQAVLGVTIVSKSEWGGRSATSKTSLASYLSYAVIHHTAGNYCSTKAACITQLKNIQAYHMDSLGWADIGYNFLIGGDGNVYEGRGWNVMGAHATNWNSKSIGISFLGNYNTNTLTSAQITAAKGLLSDAVSRGQIVSGYILYGHRQVGSTECPGTNIWNEIRTWSNWKA
What is the function of this protein?
N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN).  Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments.  Has no direct bacteriolytic activity (By similarity).
What are the official names of this protein?
Peptidoglycan-recognition protein SC2.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRL2_ARATH
Sequence: MTMIALNREVETQSLKKLSLKSVRRAREIFSPVHGQFPQPDPESKRIRLCHKIQVAFGGVEPASKPTRIADHNSEKTAPLKALALPGPKGSKELRKSATEKALVVGPTLPPRDLNNTGNPGKSTAILPAPGSFSERNLSTAALMERMPSRWPRPEWHAPWKNYRVLQGHLGWVRSVAFDPSNEWFCTGSADRTIKIWDVATGVLKLTLTGHIGQVRGLAVSNRHTYMFSAGDDKQVKCWDLEQNKVIRSYHGHLHGVYCLALHPTLDVVLTGGRDSVCRVWDIRTKMQIFVLPHDSDVFSVLARPTDPQVITGSHDSTIKFWDLRYGKSMATITNHKKTVRAMALHPKENDFVSASADNIKKFSLPKGEFCHNMLSLQRDIINAVAVNEDGVMVTGGDKGGLWFWDWKSGHNFQRAETIVQPGSLESEAGIYAACYDQTGSRLVTCEGDKTIKMWKEDEDATPETHPLNFKPPKEIRRF
What is the function of this protein?
Pleiotropic regulator.
What are the official names of this protein?
Protein pleiotropic regulator PRL2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRL1/PRL2 family.
Protein: MAT1_COCHE
Sequence: MAHARDPTGAEIARFIATRTGAQMVQLMRCIKEPAAQAAFTAKLLVVPPAVSGRPATPEKARKALNAFVGFRCYYVTIPMFKSWPMKKLSNLIGLLWEADPNKSLWSLMAKAWSTIRDQIGKDQAPLDQFFRIICPHLKLPDPASYLEIHGWILTVNEEGDPTISRSADSEFVSIGTGNTDVALSVEDIITYVQSLGYAHGFILDDNKPSSTFLGQSVSSTLEKNTSAISVTQATPNAAHARFLVRNKRRAKRQAVRNASYRASLDQDILIAHQFNPAPVDEHMPDCHSNTAPVLDQCHNPSPNQFYDGITTLLSDQIPTGQGDAGHLDNAHLFNDYSLPGDVSFITIDDFTTNMPNLIDYDAFRLGADEDVALPIFDDITHI
What is the function of this protein?
Required for mating.
What are the official names of this protein?
Mating-type protein MAT-1.
What is the protein family that this protein belongs to?
Belongs to the MATALPHA1 family.
What are the subcellular locations of this protein?
Nucleus.