PharMolix/UniProtQA huggingface dataset:
Protein: SYS_PSEF5
Sequence: MLDSKLLRSNLQDVADRLASRGFALDVARIEALEEQRKTVQTRTEQLQAERNARSKSIGQAKQRGEDIAPLMADVERMGNELSSGKAELENIQSELDSILFGIPNLPHESVPVGEDEDGNVEVRRWGTPTAFDFPIKDHVALGETHGWLDFETAAKLSGARFALLRGPIARLHRALAQFMINLHTGEHGYEEAYTPYLVQAPALVGTSQLPKFEEDLFKITREGEADLYLIPTAEVSLTNIVAGEILDAKQLPLKFVAHTPCFRSEAGASGRDTRGMIRQHQFDKVEMVQVVEPSTSMEALEGLTANAEKVLQLLQLPYRVLALCTGDMGFSAVKTYDLEVWVPSQDKYREISSCSNCGDFQARRMQARFRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGSIRVPDVLKPYMGGLEVIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STHA_YERPP
Sequence: MQQHFHFDAIVIGSGPGGEGAAMGLVKQGARVAVIERYNNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDNARTIKSSFADILNHADRVINQQTRMRQGFYDRNHCHMFSGDASFIDANTVNVRYADGTSDTLQADNIVIATGSRPYRPVNVDFNHERIYDSDTILQLSHEPQHVIIYGAGVIGCEYASIFRGLSVKVDLINTRDRLLAFLDQEMSDALSYHFWNNGVVIRHNEEFEQIEGTTDGVIVHLKSGKKVKADCLLYANGRTGNTSGLGLENIGLEADSRGLLKVNSMYQTALSHVYAVGDVIGYPSLASAAYDQGRIAAQAMIKGEANVHLIEDIPTGIYTIPEISSVGKTEQELTAMKVPYEVGRAQFKHLARAQIVGMDTGSLKILFHRETKQILGIHCFGERAAEIIHIGQAIMEQKGEGNTLEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_CLOPS
Sequence: MKIFYKAINMTLSMFTVIPLPKYEWDDRAAKHIMKLYPFIGLIIGILWYLSFFVLSKLNVPIMLMAALILTVPYILTGFLHLDGFMDVSDALLSRRDKETKLRILKDSTVGAFSVISVVLLLLVEFAGIFTVLNKNLDMRILIFIPIASRTMNGYFIVSQEMLGQSSLAKFFKEGTGKVDEIILLGIYVLVALITFFTLGINYLIAILAMGLISFILLLKVKKELGGINGDVAGYILVLMEFTGILLLGII
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SULA_SHIBS
Sequence: MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHTTRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: IL6RA_PIG
Sequence: MLAVGCALLTALLAAPGMALAPRGCSKLEVAQDVLTSLPGASVTLTCPGGEPGDNATIHWVLRNQVTGSPDGRPAGVGRRLLLKSVQLSDSGNYSCYQDGVPAGSVRLLVDAPPEEPQLSCFRKSPLSNVGCEWRPRSPPSPTTKAVLLVRKFQNSPVEDFQEPCQYSLEAQRFFCQLAVPEGDNSFHIVTLCVANSAGSQSSTPQTFEGYGILQPDPPVNITVSAVDRNPRWLSVTWQDPPSWNSYFYRLQFELRYRAERSKTFTTWMVKELQHHCIIHDAWSGMRHVVQLRAQEEFGHGLWSEWSQEVTGIPWTESRSSPAETELPLSTQAPTTNEDDEDISSKESANATSLPVQDSASVPLPTFLVAGGSLAFGTLLCIGIILRFKKTGQLQALKEGKTNMHPPYSLGQLVPERPKSTPVLVPLISPPVSPNSLGDNTSRNSRPEARGPQSPYDVSNRDYFFPR
What is the function of this protein?
Soluble form of IL6 receptor (sIL6R) that acts as an agonist of IL6 activity (By similarity).  The IL6:sIL6R complex (hyper-IL6) binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL6R in a process called IL6 'trans-signaling'.  sIL6R is causative for the pro-inflammatory properties of IL6 and an important player in the development of chronic inflammatory diseases.  In complex with IL6, is required for induction of VEGF production (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration.  'Trans-signaling' in central nervous system regulates energy and glucose homeostasis (By similarity).
What are the official names of this protein?
Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 3 subfamily.
What are the subcellular locations of this protein?
[Interleukin-6 receptor subunit alpha]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Soluble interleukin-6 receptor subunit alpha]: Secreted.
Protein: VATE_IGNH4
Sequence: MVKVEFAGDVKNLTSYIEKDAKAKIDSVVEEAVKEAEKLLNEKKEELLERAVVDVEKLLSDAQARLSAEKSSIDMEVRRKVEERKKELFQKVVEEAWKRALEEAEKKTERYKKFLEKVLIAMSNEAGEDEVIAYVRADDLEDVRAMVQEKGLKNVVEVKDVKEVGREIKGGVLGKSKSGGVWYNYTLEKAFDELLREVYPKVLEALGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: EIF3E_AEDAE
Sequence: MAKFDLTAKNCQYLDRHLTFPLLEFLLQKDIYDQTSLLKFILQTVSKTNMVDYTMDIRERLNMGDELPEELSKRRANVLVKLKELQTEVAPLMKCMEELKNPDSMKDSKSIVHALQQEFDFKHDIIKSAQKLAKYLYECGNYRDSISYLYICLLVMEPADKNYLTVLWGKLAAEILVLNWPTALEDLTRLRDFIDNHNFSPIEVLQQRTWLIHWSVLVFFNHAKGRDLIIEMFLYKPLYLNAIQTMCPHILRYLATAVIINRGRRNALKDLIKIIQQESYTYRDPITEFLEHLYVNFDFEGARMKLHECQTVIVNDFFIIGCLQEFIENARLMIFETFCRIHQCITIGMLADKLNMEPDEAECWIVNLIRNARLDAKIDSKLGHVVMGTQPLSPYQQLVEKIDSLSVRSEALTVLVERKQKAKTQESGEGNWKYY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e, Eukaryotic translation initiation factor 3 subunit 6.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPPF_HAEIN
Sequence: MTNEVKENTPLLNAIGLKKYYPVKKGLFAKPQQVKALDGVSFQLERGKTLAVVGESGCGKSTLGRLLTMIEEPTKGELYYKGHNFLENDSETKALRRKKIQIVFQNPYASLNPRKKIGSILEEPLIINTKLSAKERREKVLSMMEKVGLRAEFYDRYPHMFSGGQRQRIAIARGLMLDPDVVVADEPVSALDVSVRAQVLNLMMDLQDELGLSYVFISHDLSVVEHIADEVMVMYLGRCIEKGTTEQIFSNPQHPYTKALLSATPRLSPNLRRERIKLTGELPSPINPPKGCAFNPRCWKATEKCRENQPHLEQHTDGKLIACFHID
What is the function of this protein?
Part of the ABC transporter DppBCDF involved in dipeptide transport.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Dipeptide transport ATP-binding protein DppF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEU3_BACLD
Sequence: MKKRIALLPGDGIGPEVLDAAVDVLKSVAEHYQHEFEFEYGLIGGAAIDEAGAPLPEETVAACKAADAILLGAVGGPKWDQNPSELRPEKGLLAIRKQLDLFANLRPVKVFESLAGASPLKTEYIEGVDFVIVRELTGGLYFGKPSEQYVNQNGEEEAVDTLFYKKSEMERVIREAFQMAQSRKGKVTSVDKANVLESSKLWRKTAEEVAKEFPDVKLEHMLVDNAAMQLIYAPGQFDIIVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLYEPVHGSAPDIAGQNIANPLAAILSAAMMLRTSFGLEAEAQAVEHAVDQVLRAGKRTKDLAKGSEHCTTQSITGEVKAALADDNAISNIMTAYV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_ANAPZ
Sequence: MQLVGMVALMVGVLVSVAYLVYMERKVMAFMQLRHGPSVVGPWGLLQPFSDALKLLAKECIIPFKSRGWAFFAAPVITFALALAGWAVIPLGATEVIRDGVVVVMPYVVADLNLGVLYVLAISSLEVYGIIMAGWASGSNYAFLGAIRSVSQMISYEMSMGLVMLSVSLCAGSLRLTDIVVARHAMPYWMDLLLLPMAGVFFVSMLAETNRHPFDLPEAESELVSGYNVEYSSMSFAMFFLGEYANMILVSAMMVVLFLGGWYPPLNIHILYYIPGFVWFCSKVFLLLFCFIWVRSTVPRYRYDQLMRLGWKVFLPFSFVWVMVISGVLLWVKALPGMQN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ESTS_DROVI
Sequence: MTQILLPIALLCLFAASTLSNPLLVELPNGELRGRDNGFYYSYESIPYAEPPIDDLCLEEPRPYTERWENTFDATRPPVDCLQWSQLISQPNKLTGSEDCLTVSIYKPKNLTRISFPVVAHIFGGGWSFGAAIDDGVRPFSSSGNVIVVKTTTEWERLGFMSTGDSVIPGNFGLKDQRLAIKWIRNNIARFGGDPHNIILLGFSTGGSSVHLQLMHKEYGQLVKGAISISGTATVPWAVQANARDLAFRYGKLLGCNNPKNSRELKDCLKKTDAEEFVSTLRHLQVFDYVPFGPFGPVVESPEVESPFLTELPLDTIRSGNFAQVPWLASYTPENGIYNAALLLAKDANGKERIEELNTRWNELAPYFLAYPYTLKRSEMNAHSQKLKYQYLGYKNFSVVNYFDVQRLFTNELYKKGIELSLDSHRKHGASPVYAYVYDNPADKSLAQFLAKRSDISLGTGMGDDYYLLMNNPLREPLRADEKIVSWKLVKMVEDFAAHETLVYDDCVFPNNLGKKKFQLVVIGRNYCKQLEVESFARHGVQ
What is the function of this protein?
Transferred from the ejaculatory bulbs of males to the female genitals upon copulation, plays an important role in the reproductive biology.
What are the official names of this protein?
Esterase S, Est-S, Carboxylic-ester hydrolase S, Carboxylesterase-S.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPB_PSEA6
Sequence: MNHLESKFGQFGGMYVPELLIPALDQLEQAFIDAQNDPEFQKEFMELLTDYAGRPTAMTLSRNLVSNPNVKLYLKREDLLHGGAHKTNQVLGQALLTKRMGKTEVIAETGAGQHGVATALACALLGLKARIYMGAKDVERQAPNVFRMRLMGAEVIPVNAGSGTLKDAVNEAMRDWSATYDKAHYLLGTAAGPHPFPTIVREFHRMIGEETRAQIMAKEGRLPDAVVACVGGGSNAIGMFADFIDEPSVQLIGVEPAGKGLHTAEHGAAIGKGTTGILHGAYSYIMQDEDGQIEESYSVSAGLDYPAVGPQHAHLHDIGRATYAAVTDDEALYAFQLLSRKEGIIPALESSHALAHALNMADEAEDGTIIVVNLSGRGDKDLAHVHSILGGQTNE
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: MNMG_STRA3
Sequence: MTHNFAENYDIIVVGAGHAGVEASLAASRMGCKTLLATINLEMLAFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQADKALYAQTMKQTVEKQENLTLRQAMIDEILVEDGKVVGVRTATNQKFSAKSVVITTGTALRGEIILGDLKYSSGPNNSLASVTLADNLRDLGLEIGRFKTGTPPRVKASSINYEKTEIQPGDEQPNHFSFMSRDEDYITDQVPCWLTYTNTLSHDIINQNLHRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRYTEEVYVQGLSTSLPEDVQVDLLRSIKGLENAEMMRTGYAIEYDIVLPHQLRATLETKVIAGLFTAGQTNGTSGYEEAAGQGLVAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTEIGYEIGLVDEERYAIFKKRQMQFENELERLDSIKLKPVSETNKRIQELGFKPLTDALTAKEFMRRPQITYAVATDFVGCADEPLDSKVIELLETEIKYEGYIKKALDQVAKMKRMEEKRIPPHIDWDDIDSIATEARQKFKKINPETLGQASRISGVNPADISILMVYLEGRQKGRKNIN
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLMN_STRCA
Sequence: NILDGYVRXEGAWLLSRIYLDEVEGRDVVYYRT
What is the function of this protein?
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation; in ovulation it weakens the walls of the Graafian follicle.  It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5.  It cleaves fibrin, fibronectin, thrombospondin, laminin and von Willebrand factor (By similarity).
What are the official names of this protein?
Plasminogen.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasminogen subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOI_FRACC
Sequence: MGILDPYKGFGVTFGTMFKKPTTEQYPEEKKETAPRFHGRHQLNRHPDGLEKCVGCELCAWACPADAIYVEGADNTEAERYSPGERYGRVYQINYLRCILCGLCIEACPTRALTMSNDYELADDSRQDLIFTKEQLLAPLREGMEAPPHPMRLGSSETDYYTRDPDAPLPWQASGQEQVAGQAAELEAADVIARRTAGEHSRADEVPAHGAGSERPR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: WTR35_ARATH
Sequence: MTAPMILTGSGSAAERDARMAHTAMAFVQLFNGGYHVITKVALNVGVNQLVFCVCRDLLALSILAPLAYFRERKIRTPMNKSLLLSFFFLGLAGVFGNQLLFLIGLTYTNPTYAAAIQPSIPVFTFLLAVMMGTERVNLLRIEGQTKVGGTLVCVMGAVFMVVFRGPALLGDKDADFAMNNEISAKGQPEPTGWLVSGFLDLGFEQWHIGVLCLIGNCMCMATFLAIQAPLLKKYPANLSVAALSYFFGTVLMCTTAFFMVKEPLDWKLTQSEVLAVIYAGVIASALNYGLLTWSNKIIGPALVALYNPLQPAASAFLSRIFLGSPIYLGSVVGGFFIILGLYMVTWASFRERKTAVSGIGIAPHGLKTSEPLIFNGTVNRLGQLFSGLPSSSVKSAD
What are the official names of this protein?
WAT1-related protein At4g19185.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DNAJ1_THET8
Sequence: MKDYYAILGVSREASQEEIKKAYRRLALKYHPDRNPGDKEAEERFKEINEAYAVLSDPKKRAAYDRGHLEAPEYRPEDLFDLFFQEVFGVRGHRRPPRGEDLEAEVEVELQDLLHGAEKEVRYTRLVPCEACGGEGGRRTPCPTCRGQGVVESYRQSFFGTVVTRTACPHCKGRGYLLAETCPACRGRGRVPREERVRVQVPPGMDEGHLLRVPGYGNLGPGGPGDLYLRIRVRPHPHLERQGPDLVYRLRLGLAQAALGARVEVPGLEGPIPLDIPPGTGHGEVFALEGGGLPLPGGRGRGTLRVVVELAVPKKLSPKAQKLLRAYAEEVGEEVAPEGFWERLKGFFRK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ 1.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAX_LISMF
Sequence: MTGKITTLLFDLDGTLINTNELIIKTFQVTFQEFMPDRVFTREDILPFIGPSLMETFREINPAHADEMRAFYREYNLKHHDDLILEYDGVYEAIRALYEEDYKLGIVSTKMYDTIMRGLKVTGLDKFFQVVIGLDQVSNAKPDPEGIEMALSLLNATKEEAIMIGDNYHDIEAGKNAETLTAGVAWAIKGPEHLAQFQPDFMLEKMSDLLAIVRDEE
What is the function of this protein?
Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P.  Might play a role in controlling the intracellular pyrophosphate pool.
What are the official names of this protein?
Pyrophosphatase PpaX.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PpaX family.
Protein: RL5_STUS1
Sequence: MARLKEVYRKEIAPKLKEELQLKNVMEVPRITKITLNMGIGEAIGDKKIIDNAVADLEKITGQKVVVTHARKSIAGFKVREGWPIGVKVTLRSDRMYEFLDRLLSISLPRVRDFRGLNAKSFDGRGNYSMGVKEQIIFPEIDYDKIDALRGLDITLTTTARTDDEGRALLRAFNFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ASTB_SALG2
Sequence: MTAHEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAVKQGLLKMKALADAGFLQAVIPPHERPFIPALRQLGFTGSDEQILDKVARQAPRWLSRVSSASPMWVANAATVCPSADALDGKVHLTVANLNNKFHRALEAPVTEALLRAIFRDENQFSVHSALPQVALLGDEGAANHNRLGGEYGSAGVQLFVYGREEENEIRPARYPARQSREASEAVARLNQVNPQQVIFAQQNPEVIDQGVFHNDVIAVSNRQVLFCHEAAFARQKVLINQLRTRVDGFMAIEVPAEEVSVSDAVATYLFNSQLLSRDDGSMLLVLPRECQDHAGVWRYLNKLVAEDNPIIAIQVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDALFTALNAWADRYYRDRLTAADLADPLLLREGREALDVLTRLLDLGSVYPFQQTGAADG
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: GANA_EMENI
Sequence: MILSSLLPLSLVTLTSAALTYRGADISSLLIEEDSGVAYKNLNGETQAFELILANNGVNSIRQRIWVNPSDGSYNLEYNLELAKRVQDAGMSVYLDLHLSDTWADPGDQATPSGWSTTDIDTLAWQVYNYTLDVCNTFAENNVAVEIVSIGNEIRNGLLHPLGSTDHYDNIARLLHSGAWGVKDSSLSTTPKILFHLDNGWDWDAQKYFYDTVLATGTLLSTDFDLIGVSYYPFYNADATLSSLKTSLTNLKSNYGKNVLVVETDWPVQCSSPEYAFPSDLSSIPFSADGQETFLGRLADTLEDVGGVGIYYWEPGWVDNAGLGSSCEDNLMVDWRDRTVRESISVFGDL
What is the function of this protein?
Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.
What are the official names of this protein?
Arabinogalactan endo-beta-1,4-galactanase A, Endo-1,4-beta-galactanase A, Galactanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 53 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IMA5_PONAB
Sequence: MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIFQQCEAPMEGFQL
What is the function of this protein?
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1.  Binds specifically and directly to substrates containing either a simple or bipartite NLS motif.  Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).
What are the official names of this protein?
Importin subunit alpha-5, Karyopherin subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y4103_VIBPA
Sequence: MNAISLVQGDITTAHVDAIVNAANPRMLGGGGVDGAIHRAAGPALINACYAVDDVDGIRCPFGDARITEAGNLNARYVIHAVGPIYDKFADPKTVLESAYQRSLDLALANHCQSVALPAISCGVYGYPPQEAAEVAMAVCQRPEYAALDMRFYLFSEEMLSIWQHALTQH
What are the official names of this protein?
Macro domain-containing protein VPA0103.
Protein: CASP3_RABIT
Sequence: MENNETSVDAKSIKNLETQTIHGSKSMDSGKYLDNSYKMDYPEMGLCIIINNKNFHKNTGMSSRSGTDVNAANLGETFMNLKYEVRNKNDLTREEIMELMYNVSKEDHSKRSSFICVILSHGDEGVIYGTNGPIELKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDSGIETDSGVDYDMACQKIPVEADFLYAYSTAPGYYSWRNSEEGSWFIQSLCAMLKEYAHKLEFMHILTRVNRKVATEFESYSLDATFHAKKQIPCIVSMLTKELYFYH
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.  At the onset of apoptosis, it proteolytically cleaves poly(ADP-ribose) polymerase PARP1 at a '216-Asp-|-Gly-217' bond.  Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain.  Cleaves and activates caspase-6, -7 and -9.  Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).  Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes (By similarity).  Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress.  Acts as an inhibitor of type I interferon production during virus-induced apoptosis by mediating cleavage of antiviral proteins CGAS, IRF3 and MAVS, thereby preventing cytokine overproduction.  Also involved in pyroptosis by mediating cleavage and activation of gasdermin-E (GSDME) (By similarity).  Cleaves XRCC4 and phospholipid scramblase proteins XKR4, XKR8 and XKR9, leading to promote phosphatidylserine exposure on apoptotic cell surface (By similarity).
What are the official names of this protein?
Caspase-3, CASP-3, Apopain, Cysteine protease CPP32.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm.