PharMolix/UniProtQA huggingface dataset:
Protein: AHPC_SALTI
Sequence: MSLINTKIKPFKNQAFKNGEFIEVTEKDTEGRWSVFFFYPADFTFVCPTELGDVADHYEELQKLGVDVYSVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTGALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAAHPGEVCPAKWKEGEATLAPSLDLVGKI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, Alkyl hydroperoxide reductase protein C22, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_ACIAC
Sequence: MSLRPLHDRVIVKRIESETTTASGIVIPDNAAEKPDQGVVLAVGPGKKNDKGELSVLSVKVGDRVLFGKYSGQTVKVNGDELLVMKEDDLFAVVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM11_CANAW
Sequence: MSDLLHKLNFKIADASPEYKQRRKIQMIRFFTASAVTIFASRFAYRATVSRQYIPTLFQGNHSPPLSYNFTTDAAVAVGTGTLLCGSVTGMTVFGLCWILDVSNIKEFGWRMKSMLGGWESEKKLSEAPMDEESSYIQDSLNDILDGKYDFENDTEEVAGELKTN
What are the official names of this protein?
Altered inheritance of mitochondria protein 11.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YLJB_ECOLI
Sequence: MNQKFEAVNAIDRNVTDVADANDR
What are the official names of this protein?
Protein YljB.
Protein: MYG_PIG
Sequence: MGLSDGEWQLVLNVWGKVEADVAGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGNTVLTALGGILKKKGHHEAELTPLAQSHATKHKIPVKYLEFISEAIIQVLQSKHPGDFGADAQGAMSKALELFRNDMAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: WDR26_DANRE
Sequence: MQSNGTGQEQNHPANTQNGDANGLQSNAGSASGASGTGSGSLKKKKRLSQAEEDVIRLIGQHLHGLGLNQTVDLLMQESGCRLEHSSATKFRNHVMEGEWDKAENDLNELKALMHSPNAIVRMKFLLLQQKYLEYLEDGKVLEALQVLRGELTPLKYNTDRIHVLSGYLMCSHAEDLKAKAEWEGKGAGSRCRLLDKLQTYLPPSVMLPPRRLQTLLRQAVELQRDRCLYHNTKLDSSLDSVSLLLDHVCSRKQFPCYTQQILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVEPDTHQLKLLRTLEGHAYGVSYLAWSPDDVYLIACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDLDGNLLESWEGVRVQCLWCMGDGRTVLASDTHQRIRGYSFEDLTDRNIVQEDHPIMSFTVSKNGRLALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIVELTGHTRTVNCVSWNPCIPSLMASASDDGTVRIWGPAPFLDAQELDGLTESCSSMDS
What is the function of this protein?
G-beta-like protein involved in cell signal transduction.  Acts as a negative regulator in MAPK signaling pathway.  Functions as a scaffolding protein to promote G beta:gamma-mediated PLCB2 plasma membrane translocation and subsequent activation in leukocytes.  Core component of the CTLH E3 ubiquitin-protein ligase complex that mediates ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Acts as a negative regulator of the canonical Wnt signaling pathway through preventing ubiquitination of beta-catenin CTNNB1 by the beta-catenin destruction complex, thus negatively regulating CTNNB1 degradation.  Serves as a scaffold to coordinate PI3K/AKT pathway-driven cell growth and migration.  Protects cells from oxidative stress-induced apoptosis via the down-regulation of AP-1 transcriptional activity as well as by inhibiting cytochrome c release from mitochondria (By similarity).  Protects also cells by promoting hypoxia-mediated autophagy and mitophagy (By similarity).
What are the official names of this protein?
WD repeat-containing protein 26.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: THIG_DEIRA
Sequence: MNTNDLLTIGGQSFSSRLLLGTGKYRDFAVMQDALGASGTQIVTVAIRRVELKAPGHDGLLDALDLDRFQLLPNTAGCRTAEEAVRVAKLARAATGVSWLKLEVIPDPKYLLPDPIGTLRAAEILVGEGFTVLPYVQPDGVLARALEAVGCATVMPLASPIGTGKGLRTPELIRTVIDGAGVPIVVDAGLGVPSDAAQALELGADAVLVNTAIAEARDPVAMARAFALGVEAGRLGYLAGRMQQRDSASPSSPAAGVVRLPDPEVPA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RVE1_ARATH
Sequence: MASSPLTANVQGTNASLRNRDEETADKQIQFNDQSFGGNDYAPKVRKPYTITKERERWTDEEHKKFVEALKLYGRAWRRIEEHVGSKTAVQIRSHAQKFFSKVAREATGGDGSSVEPIVIPPPRPKRKPAHPYPRKFGNEADQTSRSVSPSERDTQSPTSVLSTVGSEALCSLDSSSPNRSLSPVSSASPPAALTTTANAPEELETLKLELFPSERLLNRESSIKEPTKQSLKLFGKTVLVSDSGMSSSLTTSTYCKSPIQPLPRKLSSSKTLPIIRNSQEELLSCWIQVPLKQEDVENRCLDSGKAVQNEGSSTGSNTGSVDDTGHTEKTTEPETMLCQWEFKPSERSAFSELRRTNSESNSRGFGPYKKRKMVTEEEEHEIHLHL
What is the function of this protein?
Morning-phased transcription factor integrating the circadian clock and auxin pathways.  Binds to the evening element (EE) of promoters.  Does not act within the central clock, but regulates free auxin levels in a time-of-day specific manner.  Positively regulates the expression of YUC8 during the day, but has no effect during the night.  Negative regulator of freezing tolerance.
What are the official names of this protein?
Protein REVEILLE 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_CHLMU
Sequence: MVLSCELTLKELLESGAHFGHQTSRWNPKMKPFIFEEKNGLYIIDLAKTLAQLKKAVSCIQKTVEQGKSILFVGTKKQAKQIIKEAAIECGEFFASERWLGGMLTNMATIRNSVKTLNNIEIDLASSNSVLTKKETALLAKRHRKLLNNLEGVRHMNSLPGLLVVIDPGYERIAVAEAGKLGIPVMALVDTNCDPTPINHVIPCNDDSIKSIRLIVNALKDAIIDTKKRSGFEILSPVRPIERPAEEIVEGLPLPNEAQNDANSKEGFLVWTDTDNSEALR
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: WOS2_SCHPO
Sequence: MSLNTQIPEVLWAQRSNKDDAEKNVIYLTVLIPDAVDPKINLTPEKLVIDSKSGANAHYAVQIDFFKDIDVEKSKYSVTGRYIFFVLYKKELQEEFWPRLTKEKLRLHWLRTDFDRWVDEDEQEAQPEVSPFGAGGMPDLSALGGMGGMDFSQFGNLGGAGAGEDASDSEPELEEEEEVGSNEKKE
What is the function of this protein?
Cell cycle regulatory protein that interacts with cdc2 in the control of the M-G1 transition.
What are the official names of this protein?
Protein wos2, p21.
What is the protein family that this protein belongs to?
Belongs to the p23/wos2 family.
Protein: Y2435_MYCLE
Sequence: MSSCPESGSTFEYVANSHLEPVHPGEEVDLDFTREWVEFYDPDNSEQLIAADLTWLLSRWTCVFGTPACRGTVAGRPDDGCCSHGAFLSDDADRTRLDDAVKKLSHDDWQFREKGLGRKGYLELDEHDGQSQFRTRKHKNACIFLNRPGFPIGAGCALHSKALKLGVPPRTMKPDICWQLPIRHSQEWVTRPDGTEILKTTVTEYDRRSWGSGGADLHWYCTGDPASHVDSKQLWESLADELTELLGAKAYAKLAAICKRRNRLGIIAVHPATQEAK
What are the official names of this protein?
Uncharacterized protein ML2435.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv0495c and S.coelicolor SCO3349.
Protein: CAPSH_BPT4
Sequence: MTIKTKAELLNKWKPLLEGEGLPEIANSKQAIIAKIFENQEKDFQTAPEYKDEKIAQAFGSFLTEAEIGGDHGYNATNIAAGQTSGAVTQIGPAVMGMVRRAIPNLIAFDICGVQPMNSPTGQVFALRAVYGKDPVAAGAKEAFHPMYGPDAMFSGQGAAKKFPALAASTQTTVGDIYTHFFQETGTVYLQASVQVTIDAGATDAAKLDAEIKKQMEAGALVEIAEGMATSIAELQEGFNGSTDNPWNEMGFRIDKQVIEAKSRQLKAAYSIELAQDLRAVHGMDADAELSGILATEIMLEINREVVDWINYSAQVGKSGMTLTPGSKAGVFDFQDPIDIRGARWAGESFKALLFQIDKEAVEIARQTGRGEGNFIIASRNVVNVLASVDTGISYAAQGLATGFSTDTTKSVFAGVLGGKYRVYIDQYAKQDYFTVGYKGPNEMDAGIYYAPYVALTPLRGSDPKNFQPVMGFKTRYGIGINPFAESAAQAPASRIQSGMPSILNSLGKNAYFRRVYVKGI
What is the function of this protein?
Major capsid protein that self-associates to form hexamers, building most of the capsid in association with pentons made of the capsid vertex protein and one dodecamer of the portal protein.  The major capsid protein self-associates to form 160 hexamers, building most of the T=13 laevo capsid.  Folding of major capsid protein requires the assistance of two chaperones, the host chaperone groL acting with the phage encoded gp23-specific chaperone, gp31.  The capsid also contains two nonessential outer capsid proteins, Hoc and Soc, which decorate the capsid surface.  Through binding to adjacent gp23 subunits, Soc reinforces the capsid structure.
What are the official names of this protein?
Major capsid protein, Gene product 23, Major head protein, gp23.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae major capsid protein family.
What are the subcellular locations of this protein?
[Major capsid protein]: Virion. Note=Part of the capsid icosahedric shell of the immature virion. The capsid is made of 930 copies arranged as 160 hexamers. SUBCELLULAR LOCATION: [Mature major capsid protein]: Virion. Note=Part of the icosahedric capsid shell of the mature virion.
Protein: ISPE_BURA4
Sequence: MTDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARVTDVPGVPEESDLVVRAANLLKAHTGTAAGVDIEIDKCLPMGAGLGGGSSDAATTLLALNRLWQLDLSRTELQSLAVKLGADVPFFVFGKNAFAEGIGEELAEVELPTRWFLVVTPRVHVPTAEIFSDELLTRNTKPVTIADFLAQQNSDAGWPDSFGRNDMQQVVTSKYAEVAQVVKWLYNVTPARMTGSGASVFAAFQSKHEAEAAKAQLPTGWNGAVAESLNEHPLFAFAS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RRF_AFIC5
Sequence: MTTNGFDINDLKRRMDGAKESLRYELGGLRTGRAAISMLEPVQVEAYGSHMPLNQVATVSVPEPRLLSVQVWDKSMVKAVETAIVNSNLGLNPATEGQVIRLRIPELNEERRKELVKVAHKYAEAARVAVRHVRRDGLDIVKKDKMSEDEQERASGEIQKVTDAAIADIDKLLATKEKEILTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_STRA5
Sequence: MKHSSWHDLIKRELPNHYYNKINTFMDAVYESGIVYPPRDKVFNAIQITPLENVKVVIIGQDPYHGPQQAQGLSFSVPDNLPAPPSLQNILKELAEDIGSRSHHDLTSWAQQGVLLLNACLTVPEHQANGHAGLIWEPFTDAVIKVVNQKETPVVFILWGGYARKKKSLIDNPIHHIIESPHPSPLSAYRGFFGSRPFSRTNHFLEEEGINEIDWLN
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_DECAR
Sequence: MARIAGVNIPNHQHAEIALTAIFGIGRTRAQKICDAAGVGRNVKMKDLSDSDMDRLRDEVGKFTVEGDLRREVTMNIKRLMDLGCYRGLRHRKGLPCRGQRTRTNARTRKGPRKAIAGKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: Y1816_NEIM0
Sequence: MNVSFAPLFLVTLILLGVVSNNNSITISATILLLMQQTALIQFVPLVEKHGLNLGIILLTIGVLSPLVSGKAQVPPVAEFLNFKMISAVFIGIFVAWLAGRGVPLMGQQPVLITGLLIGTVIGVAFMGGIPVGPLIAAGILSFVVGKG
What are the official names of this protein?
UPF0756 membrane protein NMCC_1816.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ULAA_SHIFL
Sequence: MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKGTIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIDRMGDAYSWVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTIICTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASLIAYKVAPFLGKKEESVEDLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVHWTVYILQTGFSFAVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGTIGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEIFGCVWVVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRALRAEEDAEKQLAEQSA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIC component, Ascorbate-specific permease IIC component UlaA.
What is the protein family that this protein belongs to?
Belongs to the UlaA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SURE_ANAMM
Sequence: MRVLLTNDDGFDSVGMRVLRDVVSGHFAEVWVSAPARDCSAASRALSVRTPIKTHMRGEREFVVHGTPADSAVIGICEMTSTGKRPDLVISGINYGANTGFTVPYSGTIAAAAAAFDIGVPAIAISQQYNGKRCDNNVETSWQNSRKSVMALVSRLLRDTMWHGKCVMSINVPYSDVQGVKFAGHSCDDGHIKWDGPSMERREITSGDGRCVSYVFDDMRSPNSNDNASDTQLLEQGYIVVTPIGHSMTDHAILDKYCGLQ
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTN84_ARATH
Sequence: MTTKRAYKLQEFVAHSAAVNCLKIGRKSSRVLVTGGEDHKVNLWAIGKPNAILSLYGHSSGIDSVTFDASEVLVAAGAASGTIKLWDLEEAKIVRTLTGHRSNCISVDFHPFGEFFASGSLDTNLKIWDIRKKGCIHTYKGHTRGVNVLRFTPDGRWVVSGGEDNIVKVWDLTAGKLLTEFKSHEGQIQSLDFHPHEFLLATGSADRTVKFWDLETFELIGSGGPETAGVRCLSFNPDGKTVLCGLQESLKIFSWEPIRCHDGVDVGWSRLSDMNVHEGKLLGCSYNQSCVGVWVVDLSRTEPCMAGDTAQSNGHPEKRSCSGRDPVVLNDNNSKTVLGKLSVSQNVDPLLKETKSLGRLSVSQNSDPSTKETKSIGRSSTSQNSESSMKESKPLGRLSVSQNSDVSKESRTFSSTGSLPGTPHRVSSTNVSKATSGVSTAVSNAATSRRNFTKANPKANPVNKAADFAPVIVPRADPRIEQATESRAELDIIARTMPYSLQAADSRRSPSSRNNPDLPDASVLEMSESQPVEPNNIPDGGTLPGGKVGMRGATERSINDFRYKRYGRSNSRSRMGSPPRNHDENYDLVSHRSNRDPSPTESQKGGRFQSLVINRERRGRFSNFEGPVSNFSSGNMPAPNIRPSNMFKQRGNHMPVEQGIDSPSEENIVEDIMGKHNQFVSSMQSRLAKLQVVRRYWERNDVKNSIGSIEKMADNAVTADVLGIITERNEILTLDNCTSLLPLLTALLGSGMDQHLSVSLDLLLKLVRLYGSPIYSSLSAPASVGVDIEAEQRIERYSRCFVELEKVKACLPSLARRGGLVAKSVLELNLAFQEVSS
What is the function of this protein?
May participate in a complex which severs microtubules in an ATP-dependent manner (By similarity).  This activity may promote rapid reorganization of cellular microtubule arrays (By similarity).  Confers precision to microtubule (MT) severing by specific targeting of KTN1 to MT cleavage sites such as crossover or branching nucleation sites (PubMed:28978669).  Together with other KTN80s, regulates cell elongation by modulating MT organization (PubMed:28978669).
What are the official names of this protein?
Katanin p80 WD40 repeat-containing subunit B1 homolog KTN80.4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat KATNB1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Present in dynamic discrete particles specifically localized to microtubule (MT) crossovers and branching nucleation sites.
Protein: AAS_ECO55
Sequence: MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGILLGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQITLHILPPTQVEMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COAE_CHLAB
Sequence: MLELLKVSITGDLSSGKTEACRVFQELGAYVISADKVSHSFLVPHSHIGRRVIDLLGPEVVIDNTFDRKVIAEKVFGNLDLLQALEAILHPEVCRIIEEQYCQVAKERKYPLFIAEVPLLYEIHYARWFDRVILITADENIRRERFTKKTNCSDLNFYQRCARFSSHEEKMMHADIVIENNGTKEELRHKVEEYFYALKGAL
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_STRP8
Sequence: MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKEREVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDLPSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQQDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVIIGSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFEATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGDMDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKSGLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQELFKSQKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFHHIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLTQSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELVLSVPTVINETFDDLSPYLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINRQDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIPLKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEPFDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQEKNFHLDMGNEILVHGIIDRIDQLSDGSLGVVDYKSSANQFDIGTFYNGLSPQLVTYLAALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKEHLSTGAYQTKNALYSNDELETLLNYNKYLYLKAVKHIKKGHFLINPYTSDGKTVQGDQLKAITRFEADLDMAQARRLVTLPAKEKKECFLTLMRKESHL
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: MINC_SALTY
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: UP11_GINBI
Sequence: ANDLVDDK
What are the official names of this protein?
Unknown protein 11.
Protein: KUNP1_ARGMO
Sequence: AKGDTRRCGYLMMRGCRGDTTATRAWGFNYEEKKCQQETVICGTGGAPRNAFETKQDCDALCEGYSGPQYSMQEMLQHLKENAKKTG
What is the function of this protein?
Tick salivary platelet aggregation inhibitor that plays an important part in the anti-hemostatic strategy of ticks.  Inhibits platelet aggregation induced by ADP (IC(50)~150 nM), collagen, and platelet activating factor (PAF) (PubMed:18070663).  Acts by binding to platelet membrane glycoprotein IIb-IIIa (ITGA2B/ITGB3) in a metal ion dependent manner (PubMed:18070663).  Does not inhibit aggregation induced by ristocecin, an agonist that aggregates platelets independently from the glycoprotein IIb-IIIa (ITGA2B/ITGB3).  In contrast to other tick platelet aggregation inhibitors, this protein does not protect ITGA2B/ITGB3 from dissociation under SDS condition, suggesting it may dissocate much faster than its orthologs (PubMed:18070663).
What are the official names of this protein?
Monogrin 1, MG1, Monogrin 1A, Platelet aggregation inhibitor, PAI.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted.
Protein: PROA_LEPBL
Sequence: MKEIEYVKELSYRAKKASRTLKSLSSFQKNKVLLELANLLEKRKSEILSANEFDLKNGKEKNLPSALMDRLLLNEKRIDSMAFAVREIVSLPDPVGEVTRGLTLPNGLELVTKRVPLGVVMVIYESRPNVTIDVGALSFKSGNACILRGGSEAFHSNEILVKLFHEILNKEGIDTSAITFVDKTDRSFMLPFLQQTPSIDVVVPRGGEGLIKFISEHSMIPVVKHDKGVCNLYIDQDADPAKVIPIVINSKVQRPGVCNATENLILHNGYPFRKELLEALAKEGVELLLDPSALSLYPKGRPVKEEDYQEEFLDLRLSVKTVSSLEEALTFIERTSSGHTEAIITEDLNAAKMFTNSLDSAALFVNCSTRFHDGAEFGLGAEVGISTGKLHVRGPMGLVHLTTTTTYVTGNGQIRN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.