PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_SULSY
Sequence: MTTLEAVILGIVEGLTEFLPISSTGHLILVSNLLGIQQTEQHKAFEVSIQLGSILAVVFLYFKKFLDTNLMKRILIAFIPTGILGFVLYKIIKSLFNPYIVVFMLVFGGLLLILIELYHKNKSYDINSIYEVPYQKAFLIGVFQSLAMVPGTSRSGATIVGGLLLGLDRKTAAEFSFMLAVPTMFMATFYDVYKNRSNFNLSDWENLIVGFVVAFISALFAIKWLLKFISNHSFIPFGIYRIILGILYYLWY
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLA2D_ARATH
Sequence: MIRGGALTHVALGLTVFLLLAVVHSQEKCSKTCIAQKCNVLGIRYGKYCGIGYFGCPGEPPCDDLDDCCMTHDNCVDLKGMTYVDCHKQFQRCVNELKQSIQESNNQKVGFSKECPYSTVIPTVYRGMNYGIFFSGIGNIIIPKKPASAGPVVEVDLARSKADTKDGLGTNQGPQTKDGSKVSVPMNPSPS
What is the function of this protein?
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.  Releases lysophospholipids (LPLs) and free fatty acids (FFAs) from membrane phospholipids in response to hormones and other external stimuli.  Plays a role in pollen development and germination and tube growth.
What are the official names of this protein?
Phospholipase A2-delta, Secretory phospholipase A2-delta, AtsPLA2-delta.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum.
Protein: TMM70_DROME
Sequence: MLGLRAMLPKGKHFAVVLGNVSRQITLPHNCRCITSASWTRPQQSQPQNFQQNRWLSVKSTKTESDDALQRIYYGTLAPRMKMVKFFSLSTSLAGLAAQPILLEQGMKIGGTGMAVFLCTVGGFFTFVTPLLLHFITKKYVTELHYNPLTEEYTATTISLLLQKIKTTFRPNDVVVPEVPGMFTSFLVNKRPLFVDPALFDDPEHYVKIMGYDKPIDFKLDLTPNPEKSKTSEEKQ
What are the official names of this protein?
Transmembrane protein 70 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the TMEM70 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: AZOR3_PSEAE
Sequence: MSRVLVIESSARQRGSVSRLLTAEFISHWKIAHPADRFQVRDLAREPLPHLDELLLGAWTTPCDGHSAAERRALERSNRLTEELRMADVLVLAAPMYNFAIPSSLKSWFDHVLRAGLTFRYAEQGPEGLLQGKRAFVLTARGGIYAGGGLDHQEPYLRQVLGFVGIHDVTFIHAEGMNMGPEFREKGLARARERMRQALETDTSLCVPLPTLR
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines (PubMed:20417637).  Preferred substrates are methyl red, amaranth and p-aminoazobenzene sulfonamide (PAABSA) (PubMed:20417637).
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 3, Azo-dye reductase 3, FMN-dependent NADH-azo compound oxidoreductase 3, FMN-dependent NADH-azoreductase 3.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: PROA_SCHPO
Sequence: MSLEENVKEAKNAFNILQTLSVEDRDDALDKIVEELRIKKSEVLAANAEDMKAAKLLAESGKLSSSMVKRLDLSSSDKYDSMVQGVLDVKSLPDPLGRVTYARSLDDGLDLYKVSCPVGLLLVIFEARPEVIINITSLAIKSGNAVVLKGGTESAKSFAALSNVVRSALGKSKVPQAAVQLVQSREEVSQLLKLDEYIDLVIPRGSTNLVRHIKDNTKIPVLGHAAGLCSMYVHEDADMELASKLVLDGKTDYPAACNAIETLLINEAVLSSHLPKIAETLTEAKVTLKCDPASLKVLKDMPKVSALVEPSVDQDYNTEFSDLILAIKTVPSLQSAMQHINTHGSKHTDCIITSSEAAANRFMAGIDASGVYWNASTRFADGFRYGYGTEVGISTNKIHARGPMGLDGLTIYKYQLRGNGQVASSYGVGPGKRAFKHTPINIDNISQVSKK
What is the function of this protein?
Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity).
What are the official names of this protein?
Probable gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, GSA dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
Protein: SFSA_METS3
Sequence: MDYVKGIFKNRPNRFIAEVEVDGKIEIAHVPNTGRCKELLVDGAAVYLKPSDNPKRKTRFTLHFVVNKGELVSLYSQEANSIVYDAILDGKIKELQGYSYHQREKQVDDSRIDIYLANQEDDCCGMEFLVDSCYIEVKGVTLIVDGEARFPDAPTERGAKHLKELIKLKNDGNRAVVFFLIQHPAGNDFRPNWENDPKFSQTLVEAENAGVEILVYKCNNTLEGIELVPKSLDYDLSRK
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: PDZD7_MOUSE
Sequence: MARGFTVGFDPLGLGELSSGSLSSVSSRGHLGSDSGSTATRYLLRKQQRLLNGPSRGIRASSPMGRVILINSPIEANSDESDIIHAVRVEKSPSGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTTMGSAVRLLTSSSCLHMMVRRMGRVPGIKFSKEKTTWVDVVNRRLVVEKCSSTPSDRSSEDGVRRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTHIMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPASESSSSVSSYASSAPCSSGSLPSDRMDVCLGPEEPTSHGPGWGRADTAMQTEPDLDSRVETWCSVRPTVILRDTAIRSDGPSSTRHLDSALSESPKTALLLALSRPRTPITRSQSHLTLWEEKKQRKKEKSGSSGEKGALQRSKTLMNLFFKGGRQGRPAGDGHREAWTLDSRSPTKVRPRLDLEKAGSVGPVQKFVTWRLRRDRERGRALLSARSGSPSGQAPTVNEQVQAWESRRPLIQDLARRLLTDDEVLAVTRHCSRYVHEGGVEDLVRPLLAILDRPTKLLLLRDIRSVVAPTDLGRFDSMVMPVELEAFEALKSRAVGPSALRPTRQDTPPKRHLITPVPDSRGGFYLLPVNSSEDEDGEIREKLGVLKVSLGASAPHHKGIPPLQDVPVDAFSLRRGACAPPPQPPPVAPRPPRPNWLLTEPLSREDTQQNQSQTPAQSCSRSRSRSRSRSHSRGQGKSPGRRRSPSPAPIATAATANGRYHRPRKARPLLPRLLDGQVAKVGARQGPLENGRIAEEAVGNVSTGALRTITLSKMKQSLGISISGGIESKVQPMVKIEKIFPGGAAFLCGDLQAGFELVAVDGESLEQVTHQRAVDTIRRAYRNKAREPMELVVRVPGPGLLPLASDLRVVKDQSLAPDCPSALGPVDDARILTQLPPPEARQLQQSLSSALKVPQSIPKLSPILKDPHDPS
What is the function of this protein?
In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links (PubMed:24334608).  Blocks inhibition of adenylate cyclase activity mediated by ADGRV1 (PubMed:24962568).
What are the official names of this protein?
PDZ domain-containing protein 7.
What are the subcellular locations of this protein?
Cell projection, cilium. Nucleus. Cell projection, stereocilium. Note=Localizes at the ankle region of the stereocilia.
Protein: SPO16_BOVIN
Sequence: MAESDGKEKIKWTTTIIISSSLKSYEVAAALENRSHKVRYSDSVENGSIIFSLSGVAFLLMDARECFMSAEETFLAKIEKFINIHQNSFLVLFAALHGPEEWKLMFRIQQRFLGSNLRILPVHNTVNAINLMCTIAKITSKSYIDSICYRMITTKAYIIEQSPVWKTLQKIKLSSDTFNPN
What is the function of this protein?
Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells (By similarity).  Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1 (By similarity).  Required for the localization of TEX11 and MSH4 to recombination intermediates (By similarity).
What are the official names of this protein?
Protein SPO16 homolog, Synaptonemal complex reinforcing element.
What are the subcellular locations of this protein?
Chromosome.
Protein: SYN_LACLS
Sequence: MKDLISIINVKDHVGETVKIGAWVADKSGKGKLQFLQLRDGTAFFQAVVFKPNMIEKFGEEEGTAKFDEIKHLSQETSVYVTGVVKEDSRSKFGYELDVTELEVIGHSHDYPITPKEHGVEFLLDNRHLWLRSKRQMAMMQVRNAIIYASYDFFAKNGFIKFDSPILSGNAAENTTELFETDYFGNSAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFVTHDESLDIQEAYVKALIQGVLDNAAYALETLERDTSMLQKYIDTPFKRVSYDDAIDLLQAHENDDDTDYEHVEHGDDFGSPHETWISNYYGVPTFIVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSERETDYDLLLKKIADFGLDPKDYDWYLELRKFGSVPHAGFGLGLERMVTFVAGTEHIREAIPFPRMINRIQP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_SERP5
Sequence: MNQTLLSDFGTPVERVERALEALRNGRGVMVLDDENRENEGDMIFAAETMTVEQMALTIRHGSGIVCLCLTEERRQQLELPMMVTNNSSQFQTAFTVTIEAAQGVTTGVSASDRLTTIRAAVADNAKPSDLNRPGHVFPLRAQPGGVLSRRGHTEATIDLVSMAGFKPAGVLCELTNDDGSMAHAPEVILFAKQHDMTVLTIEDLVAYRQAHEQKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: GLGX_SHISS
Sequence: MTRLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIEGEFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALHEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYACACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIALGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: FMT_NITMU
Sequence: MRIIFAGTPPFAAAALEALADAGHEIALVLTQPDRPAGRGMKNASSAVKLLAQKRGFGLLQPPSLRQPELHMQLEAVRADIMVVAAYGLILPFSVLNIPKLGCVNIHASLLPRWRGAAPIERAILAGDRETGITIMQMDRGLDTGPILLVRSITIAKDDTAGTLHEKLGQLGAACIVEALALLQQGKIIATPQNDLAATYASKLEKTEAEIDWRMDAENIDRAVRAFNPRPGMHSTVNGISMKVWQTSVDIAETDEKPGEIVAIRPDGIVVACGKHALILKIVQKSGGKKLRSAEFLLGHSLHPHDRFESGE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: VATM_DICDI
Sequence: MSFLRPSIWRSSPMQMVQLFVQIEAAHDTVDELGKLGLIQFLDDNEHVNLFQRNFVNEVKRCDDMEKKLKFFEDQVKKEPKLQKLLPDNMLSVVDDDSQMDELEGRFDELESELKQVNANQETLQRNYNELIQLRHVLTKDSVFFQENPNLIEGEGHEHSARSPLLAEDQHVSEVAKQGVKLGFITGVMNTDKMPQFQRSLWRTTRGNNYVKDARIEEEIIDPQTGEETAKTVFIVFFQGERLQQKIKKICESFGANIYDCPDNSFERSNLLQKVTVRITDLYEVLQRSKDHKRQTLAGIVPRLYSWKKKVLLEKSIYHTMNLFDYDVGRKCLIAKGWTPKDKIEEIQLALRTATTRSGALVPSVLSIIKTEGSPPTHFETNKYTSSFQEIVNAYGIAHYREVNPAVLTIVTFPFLFGVMFGDVGHGALLLLSALGLISLEKKLAGKKLNELIQMPFDGRYVLFLMSLFSIYVGFIYNECFSIPMNIFGSQYNLNSTTGLYTYQHTDRVYPVGVDPLWKGAPNELVYYNSFKMKLSIIFGVVQMSVGICFSLLNYLNQKGPIKIVNILTQFVPQMIFLWSIFGYMSVLIILKWVVPYRSFEVDKVDPPFILPTIIAMFLSPGGTPDVVFFSGQGAVQTALLFLALISIPVMLVIKPLFMKRFHFQEVERKKLGHHEEEHDDEALYTGHHGEEFEMGEVFVHQVIHTIEFVLGAVSNTASYLRLWALSLAHSELSSVFWERILIGQVERGNPFLAFVGFGAWLGASVAVLLLMESLSAFLHALRLHWVEFQNKFYIGDGVRFIPYSATRILSEDDE
What is the function of this protein?
Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes.  Required for assembly and activity of the V-ATPase.  Required in both the contractile vacuole system and the endosomal/lysosomal system.  Also required for cytosolic pH regulation.
What are the official names of this protein?
Vacuolar proton translocating ATPase 100 kDa subunit, Clathrin-coated vesicle/synaptic vesicle proton pump 100 kDa subunit, Vacuolar ATPase transmembrane subunit.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note=Found in membrane of contractile vacuole complex, an osmoregulatory organelle.
Protein: CNG3_CHICK
Sequence: MKVGVIETHHSHPIIPSVVVQDTSEDPGLIEKGENRFARQWYLPGAFAQYNINNNSNKDEEKKKKKEKKSKSENKKDGERQKNKEKKEKHKNKDKKKGKEEEKKKDIFIIDPAGNMYYNWLFCITMPVMYNWTMIIARACFDELQNDYLAVWFIVDYVSDVIYIADMFVRTRTGYLEQGLLVKEEQKLKEKYKSSLQFKLDFLSIIPTDLLYFKLGLNYPELRINRLLRVARMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVYYSISKAIGFGADTWVYPNTSHPEFARLTRKYVYSLYWSTLTLTTIGETPPPVRDSEYFFVVVDFLVGVLIFATIVGNVGSMISNMNAARAEFQAKIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKAVDEREVLKYLPDKLRAEIAINVHLETLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICRKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPDAKAMLEEKGKQILMKDGLLDIEVANLGSDPKDLEEKVAYMEGSMDRLQTKFARLLAEYDAAQQKLKKRLTQIEKILKPVMEQEFLDFEEADPPTDKPGVTKTE
What is the function of this protein?
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger.  This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.
What are the official names of this protein?
Cyclic nucleotide-gated channel rod photoreceptor subunit alpha, CNG channel 3, CNG-3, CNG3.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COBS_METBF
Sequence: MNSYLLAFKSGFGFLSTIPVGISMEGIDELMKKIYFYPVVGAVLGLLIGAVAFIGQVIFPGPVLAALLMGFIYYITGFNHLDGITDIGDGFMAHGSLEKKIKALKDTTIGTGGVSFCILLLLTLYGSIRAVQQEGSAVFGSNLPVLMFESMFIAEVSAKQSMLTIAAFGKPIPPREKQAYPGLGAMTINGATRKNFLIGFVFGAIVCFLPFGWIGLLPYLGACLVALVILNRSYAHFGGLNGDGIGTANEIGRVTALIILAVLLQLSLNGYMGGFKWTLL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: E4PD_IDILO
Sequence: MSEPARIAINGFGRIGRSFLRALYENGYRDSVQVVLINEPAASEAIAHLLKYDSSHGRFGEKVTQSGDALTVAGDNIALTHQTEIEAIDWRAHEVDFVVDCTGVFGSQADGQLYLQQGVKRVLFSHPGKPDVDFTAIYGVNEKELTVDHKVVSNGSCTTNCIVPVIKVLDDAFGIDSGAITTIHSAMHDQQVIDAYHPDLRRTRAAGRSIIPVDTRLARGIERILPHLEGRFEAIAVRVPTTNVTAMDLSVTLNSDATIEQINQVLREQSERQLAGILDYTEEPLVSIDFNHDPHSSIVDGTQTRVSHKRLVKLLCWCDNEWGFANRLLDTAKTMAEQTEH
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_KLEP3
Sequence: MKQFLDFLPLVVFFAFYKLYDIYAATTALIVATAIVLIYSWVRYRKVEKMALITFVLVAVFGGLTLFFHNDEFIKWKVTVIYALFAGALLFSQWVMKKPLIQRMLGKELALPQQVWSRLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLVFTLLSGIYIYRHMPQDDHH
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_LACLM
Sequence: MLVPKRVKHRREFRGKMRGYAKGGDTVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRNGQVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGVVMFELGGVDEATAREALRLASHKLPVKTKFVKRGEA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TGT_AERHH
Sequence: MKFELKTTDGRARRGQLVFERGTVQTPAFMPVGTYGTVKGMTPEEVRETGAQILLGNTFHLWLRPGQEVMRAHGDLHDFMNWQGPILTDSGGFQVFSLGHIRKITEAGVHFRHPINGEKIFLDPEKSMEIQYDLGSDIVMIFDECTPYPATYEEARKSMEMSLRWGKRSRDKFDALGNKNALFGIIQGSVYEDLRDVSLDGLLEIGFDGYAVGGLAVGEPKEDMHRILEHVCPKIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFTTDGVVKIRNAKYREDTSTLDADCDCYTCKNYTRSYLYHLDKCNEILGARLNTIHNLRYYQRVMQGLRDAIEQGKLDDFVTEFYRRQGKPVPPLAENDVK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DCTA_BURA4
Sequence: MKKKPFYKVLYVQVIFAIIVGVILGHFYPALATDMKPLGDGFIKLIKMVIGPIIFCTVVTGIAGMEDMKKVGRVGGKALLYFEVVSTFALLLGLAATHILRPGVGFNIDPATLDGKAVASYAAKAHGQSTVDFLLHIIPNTMVDAFAQGEILQILLIALLFGSVLAHLGERGKVVTDFIDGLTRVLFGIVHIVTKLAPIGAFGAMAFTIGKYGVGSLVPLLKLIGTFYLTSIVFVLVVLGTIARVTGFSIIRFVSYIKEELLIVLGTSSSEAALPQLMEKLEKAGCSRSVVGLVVPTGYSFNLDGTNIYMTMAVLFIAQATNIELTWMQQLTLLAVAMLTSKGASGVTGAGFITLAATLAVVPTIPLSGMVLILGIDRFMSECRALTNIVGNGVATVVVSAWEKELDRNKLRQALAGGGEVKTTEAAGV
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KUP1_AERHH
Sequence: MKWNFMMSHGHQQGRMAITLAALGVVYGDLGTSPLYALKESFAGHLGLQPTPEGILSIVSLFFWTIMIVVSFKYVLLVLRADDKGEGGILTLASLASRRLPAKPRALLMLLGLVGVGLFIGDAVITPAISVLSAVEGLQVITPELAPFVLPITLTVLVILFGAQHYGTAGIGRLFGPIMLLWFGVLAALGAYEIVQNPAILQAVNPLYALDFMVSRPGIAFITLGAVVLCVTGTEALYADMGHFGRGAIQLAWGSLVMPALLLNYFGQGALLLRNPAAIENPFYLLAPSWLAFPLLILATLATVIASQAVISGTYSVVRQAILLGYLPRQEIRHTSEHEIGQIYLPLVNWLLLGGIIIVIIWFQSSSNLAAAYGIAVTGTMALTTLLLMVVAARRWKWSRWLIALICAPLLLVDVTFFAANTTKFLAGGWLPILFALLAIIVMTTWKRGRELVLDKLEHKSLALKGFVDNMQAHPPLQVPGTAVFLSKSVQVVPHAMLHNLKHNKILHERVIFLTVQIKDEPWLSFKERIELTHLGEGFWQVVAHFGYKEVPSMEEIFQACAQEDLKVTMAKTSFFLSHENLVSTDLPGMARWREGLFVWMNRNSLKATDFFHIPANRVVELGVLLEL
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BH028_ARATH
Sequence: MINTDDNLLMIEALLTSDPSPPLLPANLSLETTLPKRLHAVLNGTHEPWSYAIFWKPSYDDFSGEAVLKWGDGVYTGGNEEKTRGRLRRKKTILSSPEEKERRSNVIRELNLMISGEAFPVVEDDVSDDDDVEVTDMEWFFLVSMTWSFGNGSGLAGKAFASYNPVLVTGSDLIYGSGCDRAKQGGDVGLQTILCIPSHNGVLELASTEEIRPNSDLFNRIRFLFGGSKYFSGAPNSNSELFPFQLESSCSSTVTGNPNPSPVYLQNRYNLNFSTSSSTLARAPCGDVLSFGENVKQSFENRNPNTYSDQIQNVVPHATVMLEKKKGKKRGRKPAHGRDKPLNHVEAERMRREKLNHRFYALRAVVPNVSKMDKTSLLEDAVCYINELKSKAENVELEKHAIEIQFNELKEIAGQRNAIPSVCKYEEKASEMMKIEVKIMESDDAMVRVESRKDHHPGARLMNALMDLELEVNHASISVMNDLMIQQANVKMGLRIYKQEELRDLLMSKIS
What are the official names of this protein?
Transcription factor bHLH28, Basic helix-loop-helix protein 28, AtbHLH28, bHLH 28, Transcription factor EN 40, bHLH transcription factor bHLH028.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACDSB_MOUSE
Sequence: MAVSALQLWRMGGLLRRRFPTCLSPWKIPPRVLKSSQPEALVSLTNNAVAFAPLQTLTDEEIMMKQTVKKFAQEHVAPLVSSMDENSKMEKSVIQGLFQQGLMGIEVEAQYGGTEASFFCSVLVIEELAKVDASVALLCDIQNTIINNLFRKHASEEQKATYLPKLVTEKLGSFCLSEAGAGSDSFAMKTRADKSGNYYVLNGSKMWISHAEHAELFLVFANVDPSSGYRGITCFLVDRDTEGFQIGKRENKMGIRASSTCQLTFENVKVPETNILGKIGHGYKYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERMQFGKRIFDFQGLQHQVAQVATQLEATRLLTYNAARLVEAGRPFIKEASMAKYYASEVAGLTTSKCIEWMGGVGYTKDYPVEKFFRDAKIGTIYEGASNIQLNTIAKHIDAEY
What is the function of this protein?
Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA.  Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA (By similarity).  Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway (By similarity).  Can also act on valproyl-CoA, a metabolite of the valproic acid drug (By similarity).
What are the official names of this protein?
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial, SBCAD, 2-methyl branched chain acyl-CoA dehydrogenase, 2-MEBCAD, 2-methylbutyryl-coenzyme A dehydrogenase, 2-methylbutyryl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PSBN_LOLPR
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YEEX_SALCH
Sequence: METTKPSFQDVLEFVRLFRRKNKLQREIQDIEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKSDYEDRVDDYIIKNAEISKERRDISKKLKAMGEMKHADVKAE
What are the official names of this protein?
UPF0265 protein YeeX.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: HSLV_RHIE6
Sequence: MTTIITVRKGGKVVMAGDGQVSLGQTVMKGNARKVRRIGKGEVVAGFAGATADAFTLLERLEKKLEQYPGQLMRAAVELAKDWRTDKYLRNLEAMMLVADKSTTLAITGNGDVLEPEHGTTAIGSGGNFAFAAARALMDTDKSAEEIARRALDIAADICVYTNHNIVVESLDVEG
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YG3A_YEAST
Sequence: MLFNINRQEDDPFTQLINQSSANTQNQQAHQQESPYQFLQKVVSNEPKGKEEWVSPFRQDALANRQNNRAYGEDAKNRKFPTVSATSAYSKQQPKDLGYKNIPKNAKRAKDIRFPTYLTQNEERQYQLLTELELKEKHLKYLKKCQKITDLTKDEKDDTDTTTSSSTSTSSSSSSSSSSSSSSSSDEGDVTSTTTSEATEATADTATTTTTTTSTSTTSTSTTNAVENSADEATSVEEEHEDKVSESTSIGKGTADSAQINVAEPISSENGVLEPRTTDQSGGSKSGVVPTDEQKEEKSDVKKVNPPSGEEKKEVEAEGDAEEETEQSSAEESAERTSTPETSEPESEEDESPIDPSKAPKVPFQEPSRKERTGIFALWKSPTSSSTQKSKTAAPSNPVATPENPELIVKTKEHGYLSKAVYDKINYDEKIHQAWLADLRAKEKDKYDAKNKEYKEKLQDLQNQIDEIENSMKAMREETSEKIEVSKNRLVKKIIDVNAEHNNKKLMILKDTENMKNQKLQEKNEVLDKQTNVKSEIDDLNNEKTNVQKEFNDWTTNLSNLSQQLDAQIFKINQINLKQGKVQNEIDNLEKKKEDLVTQTEENKKLHEKNVQVLESVENKEYLPQINDIDNQISSLLNEVTIIKQENANEKTQLSAITKRLEDERRAHEEQLKLEAEERKRKEENLLEKQRQELEEQAHQAQLDHEQQITQVKQTYNDQLTELQDKLATEEKELEAVKRERTRLQAEKAIEEQTRQKNADEALKQEILSRQHKQAEGIHAAENHKIPNDRSQKNTSVLPKDDSLYEYHTEEDVMYA
What are the official names of this protein?
Uncharacterized protein YGR130C.