PharMolix/UniProtQA huggingface dataset:
Protein: SYA_MYCBO
Sequence: MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLGQRTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGAIELAWALLTNSLAAGGYGLDPERIWTTVYFDDDEAVRLWQEVAGLPAERIQRRGMADNYWSMGIPGPCGPSSEIYYDRGPEFGPAGGPIVSEDRYLEVWNLVFMQNERGEGTTKEDYQILGPLPRNNIDTGMGVERIALVLQDVHNVYETDLLRPVIDTVARVAARAYDVGNHEDDVRYRIIADHSRTAAILIGDGVSPGNDGRGYVLRRLLRRVIRSAKLLGIDAAIVGDLMATVRNAMGPSYPELVADFERISRIAVAEETAFNRTLASGSRLFEEVASSTKKSGATVLSGSDAFTLHDTYGFPIELTLEMAAETGLQVDEIGFRELMAEQRRRAKADAAARKHAHADLSAYRELVDAGATEFTGFDELRSQARILGIFVDGKRVPVVAHGVAGGAGEGQRVELVLDRTPLYAESGGQIADEGTISGTGSSEAARAAVTDVQKIAKTLWVHRVNVESGEFVEGDTVIAAVDPGWRRGATQGHSGTHMVHAALRQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTDDQRTQVEEVTNEAVQADFEVRTFTEQLDKAKAMGAIALFGESYPDEVRVVEMGGPFSLELCGGTHVSNTAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKVPSEEVPARVANLVERLRAAEKELERVRMASARAAATNAAAGAQRIGNVRLVAQRMSGGMTAADLRSLIGDIRGKLGSEPAVVALIAEGESQTVPYAVAANPAAQDLGIRANDLVKQLAVAVEGRGGGKADLAQGSGKNPTGIDAALDAVRSEIAVIARVG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_BART1
Sequence: MNKVNPKNTSPVAPKKVFIKTYGCQMNVYDSQRMTDSLSSQGYVTTQTPNDADLILVNTCHIREKAAEKLYSDLGRLRVMRQERTPDKPLTVGVTGCVAQAEGSEILRRAPIVDLVIGPQMYHRLPELLEKAKQGKKIIETDYAVEDKFAHLPPHNKRAVRKRGVSAFLTVQEGCDKFCTFCVVPYTRGAEISRSVEQITEEARQLIEAGVKEITLLGQNVNGWHGQSADGKTWRLGDLLYHLAKLDGLKRLRYTTSHPRDMDDSLIAAHRDLDMLMPYLHLPVQSGSDRILKAMNRQHKSSYYLHLIEKIRAARPDIAFSGDFIVGFPGETDEDFEETIKLIQQVQYSSAYSFKYSPRPGTVGATMKNHVDESVKDARLQHLQVLLLEQQNTFLRSKIGQKTDVLIEKPGRHSGQMVGRSPWLLPVVVDTESSTGSVVEIHIKNASSNSFVGEMTNR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYCY1_HYLPI
Sequence: MALPYHIFLFTVLLPSFTLTAPPPCRCMTSSSPYQEFLWRTQRPGNIDAPLYRSFSKGSPTFTAHTYMPRTCYNSATLCMHANTQYWTGKMINPSCPGGLGVTVCWTYFTHTGMSDGGGVQDQAREKHVKEVISQLTQVHSTSSPYKGLDLSKLHETLRTHTRLVSLFNTTLTGLHEVSAQNPTNCWMCLPLDFRPYVSIPVPEQWNNFSTEINTTSVLVGPLVSNLEITHTSNLTCVKFSNTTDTTNSQCIRWVTPPTRIFCLPSGIFFVCGTSAYRCLNGSSESMCFLSFLVPPMTIYTEQDLYNYVVSKPRNKRVPILPFVMGAGVLGALGTGIGSITTSTQFYYKLSRELNGDMERVADSLVTLQDQLNSLAAVVLQNRRALDLLTAERGGTCLFLGEECCYYVNQSGIVTEKVKEIRDRIQRRAEELRNIGPWGLLSQWMPWILPFLGPLAAIILLLLFGPCIFNLLVNFVSSRIEAIKLQMEPKMESKTKNYRRSLDWPASPRSDVNDIKGIPPEEISTAQPLLRPNSAGSS
What is the function of this protein?
Endogenous envelope proteins may have kept, lost or modified their original function during evolution.  Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection.  The surface protein (SU) mediates receptor recognition, while the transmembrane protein (TM) acts as a class I viral fusion protein.  The protein may have at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of membranes (By similarity).
What are the official names of this protein?
Syncytin-1, ERV-W1 provirus ancestral Env polyprotein, ERVWE1 envelope protein, Endogenous retrovirus group W member 1, Envelope polyprotein, Syncytin.
What is the protein family that this protein belongs to?
Belongs to the gamma type-C retroviral envelope protein family. HERV class-I W env subfamily.
What are the subcellular locations of this protein?
[Surface protein]: Cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the membrane, but localizes to the extracellular surface through its binding to TM. SUBCELLULAR LOCATION: [Transmembrane protein]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Syncytin-1]: Virion.
Protein: XKR8_GASAC
Sequence: MEGATFSKYSWIDFVFSVIGACTFLVDWGSDVWLAAEFYRRGDVTWFWVLVGLMALSSFVVQTFSWFWFQYDRELPGFRAQTEAAAVLLGDRAKLSCAVHVLQLGFLCRHISAIRQGFRVWWRKEKGSEYAIYQTHDLSMLRLIETFCESAPQLTLMIYVMLHTHKARAVQFVSIAASTTSIAWMVVDYHRSLRSFLPDKAKQGWGSSLIYFLWNLLLIAPRVAALALCASVLSGYMAAHFLMLWSAFALWAWRQGTHFMDSVAGEWLYRATVGLIWYFSWFNVKDGQTRSRSAIYHSFISTDGAILLATWWCHRDPVQTQSYALALLIALPLFHFLGLLFKALYYCCFHPKLWRPPARDPGLPNDLPDAQVSMRDFPIQDGGLSPKLLNKRMAGQVARFYSDE
What is the function of this protein?
Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling.  Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment.
What are the official names of this protein?
XK-related protein 8.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MVP_PMMVS
Sequence: MALVVKDDVKISEFINLSAAEKFLPAVMTSVKTVRISKVDKVIAMENDSLSDVNLLKGVKLVKDGYVCLAGLVVSGEWNLPDNCRGGVSVCLVDKRMQRDDEATLGSYRTSAAKKRFAFKLIPNYSITTADAERKVWQVLVNIRGVAMEKGFCPLSLEFVSVCIVHKSNIKLGLREKITSVSEGGPVELTEAVVDEFIESVPMADRLRKFRNQSKKGSNKYVGKRNDNKGLNKEGKLFDKVRIGQNSESSDAESSSF
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Forms a ribonucleoprotein complex with viral RNA.  Binds microtubules and modulates microtubule stability.  Can bind double-stranded DNA.
What are the official names of this protein?
Movement protein, 30 kDa protein, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus movement protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton. Host cell junction, host plasmodesma.
Protein: CPXT1_TRIEI
Sequence: MITSNFKTQENVSQAITLASWLAGEYSSIKYTLEDARTNPHIRIFFRPLPYDFFGGIGFYSEEIYDHDPWHPHYQFVKRVIPQGDSVRVENYALKDPDLHTGAGQDLEILATLTPDNIELRKGCAMIFKRQGDTFVGGVEPGHKCLIPRGDGSMTYLVSEVKVTQKTWTSRDTGYDVNTHEKIWGSNSGPFKFDKVQDFSGEIPDIAIL
What is the function of this protein?
Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.
What are the official names of this protein?
Chromophore lyase CpcT/CpeT 1.
What is the protein family that this protein belongs to?
Belongs to the CpcT/CpeT biliprotein lyase family.
Protein: CASA1_HUMAN
Sequence: MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQTDEIKDTRNESTQNCVVAEPEKMESSISSSSEEMSLSKCAEQFCRLNEYNQLQLQAAHAQEQIRRMNENSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNNVMLQW
What is the function of this protein?
Casoxin D acts as opioid antagonist and has vasorelaxing activity mediated by bradykinin B1 receptors.
What are the official names of this protein?
Alpha-S1-casein.
What is the protein family that this protein belongs to?
Belongs to the alpha-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL28_BACTN
Sequence: MSKICQITGKKAMIGNNVSHSKRRTKRTFDLNLFNKKFYYVEQDCWISLSLCANGLRIINKKGLDAALNDAVAKGFCDWKSIKVIG
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RPO5_THEGJ
Sequence: MAGKKEFSVFMHELVPEHRVISEEEKEELLRRYRIRLSQLPQIKASDPAVVELGAKPGDVIEIKRKSPTAGVYLYYRLVVED
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DESA3_MYCTO
Sequence: MAITDVDVFAHLTDADIENLAAELDAIRRDVEESRGERDARYIRRTIAAQRALEVSGRLLLAGSSRRLAWWTGALTLGVAKIIENMEIGHNVMHGQWDWMNDPEIHSSTWEWDMSGSSKHWRYTHNFVHHKYTNILGMDDDVGYGMLRVTRDQRWKRYNIFNVVWNTILAIGFEWGVALQHLEIGKIFKGRADREAAKTRLREFSAKAGRQVFKDYVAFPALTSLSPGATYRSTLTANVVANVIRNVWSNAVIFCGHFPDGAEKFTKTDMIGEPKGQWYLRQMLGSANFNAGPALRFMSGNLCHQIEHHLYPDLPSNRLHEISVRVREVCDRYDLPYTTGSFLVQYGKTWRTLAKLSLPDKYLRDNADDAPETRSERMFAGLGPGFAGADPVTGRRRGLKTAIAAVRGRRRSKRMAKSVTEPDDLAA
What is the function of this protein?
Is likely involved in the aerobic desaturation system responsible for the synthesis of oleic acid from stearoyl-CoA; oleic acid is a precursor of mycobacterial membrane phospholipids and triglycerides.  Catalyzes the conversion of stearoyl-CoA to oleoyl-CoA by introduction of a cis double bond between carbons 9 and 10 of the acyl chain.  Requires the electron transfer partner Rv3230c to pass two electrons from NADPH to its active site diiron center.  Is also able to catalyze the 9-desaturation of palmitoyl-CoA to palmitoleoyl-CoA.
What are the official names of this protein?
NADPH-dependent stearoyl-CoA 9-desaturase, Delta(9)-stearoyl desaturase, Stearoyl-CoA 9-desaturase (NADPH), Stearoyl-CoA Delta(9)-desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OL497_MOUSE
Sequence: MAFLEVGNHTAVTEFILLGLTDDPVLRVVLFTIILCIYLVTVMGNLSTILLIRVSSQLHHPMYFFLSHLASVDMGLSSSVTPNMLLNFLIERNTISYLGCGIQQSLADFFGSVECFLLAAMAYDRFMAICNPLLYSTKMSTKVCVQLVVGSYIGGFLNASLIMFYFFSFLFCGPNRVDHFFCDFAPLVELSCSDVSVSVIVISFSAGSVTMITVFVIAVSYSYILITILKMHSIEGRHKAFSTCTSHLTAVTLYYGTITFIYVMPKSSFSTDQNKVVSVFYMVMIPMLNPLIYSLRNNEIKGAIKRQLGKKMSC
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 497, Olfactory receptor 204-9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LBD36_ARATH
Sequence: MASSSSPCAACKFLRRKCTQECVFAPYFPPDQPQKFAFVHKVFGASNVAKLLNELASNQREDAVNSLFYEAEARLRDPVYGCVGLISILQHRLKQVNHDLENAKKELATYVGPQAMLPILQPHFMSLPPQPQRPSSSSASVLTQHHHNLLPMMAIPTGQLYHQQQQQIFEAQQLAAVAREQQNEMFRAYGGGGGSSSPHHQNQAQAEILRFNNGFDSVPAGSVTVTGFNQLSSGGTAVTGMSLGGNFVDSPSTNNNYHTDQQLHHHHQPQQHHEAQLFIPSQSSQPLPLQTQETQTQTQPNSESEEGRRNVIG
What is the function of this protein?
Controls the proximal-distal patterning in petals and the adaxial-abaxial determination of leaves.  Involved in the repression of the homeobox gene BP.
What are the official names of this protein?
LOB domain-containing protein 36, ASYMMETRIC LEAVES 2-like protein 1, AS2-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
Protein: STOP2_ARATH
Sequence: MHIHMMNRDEHIAKKVEGSISSFSGETSTSSKQIYVNPVTTTGTKSMEDDDVSLSLLYNLSTLHEKVHQIQSLVSFYMVSTNNINQSSGSTSLAVANIGSLVQEIITAASSMLYTCQQLQIGSNNNNNDIDNDQTVDAMVLEFSRQETDPGHDFVQESTNLFGVQERGQISFPDQNLDWYNTETINPKKDKHRSKPSSGSYDILELDVADLLAKYTHYCQICGKGFKRDANLRMHMRAHGDEYKTREALISPTSQDKKGGYSLKKHYYSCPQHGCRWNQRHEKFQPLKSVICAKNHYKRSHCPKMYMCRRCSVKHFSVLSDLRTHEKHCGDIKWVCSCGTKFSRKDKLMSHVSLFLGHVPAHGSSKPPTITLK
What is the function of this protein?
Probable transcription factor.  Together with STOP1, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+).  Required for the expression of genes in response to acidic stress (e. g.  ALMT1 and MATE), and Al-activated citrate exudation.
What are the official names of this protein?
Protein SENSITIVE TO PROTON RHIZOTOXICITY 2, Zinc finger protein STOP2.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSH1_ENT38
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGSLATTGHPESLGSALTHKWITTDFAEALLEFITPVDGDIDHMLTLMRDVHRYTARQLGDERMWPLSMPCYIEQGQDIELAQYGTSNIGRLKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGETDKEAISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYETIGLEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGEAPSDALERGGIEYIEVRSLDINPFSPIGVDEQQIRFLDLFMVWCVLADAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCETAQFPLAKVGKDLFRDLKRVAQTMDSLYGGEEYQKVCDQLVESFDNPELTFSARILRSMIDQGIGGTGRTLAAQYRDMLQQEPLEVLSEEDFVAEREASIARQREVEAGDTESFEAFLAKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: RAD59_YEAST
Sequence: MTIQAKPSSSISYDSTTYGTAPGLDIKEFQIIEDWNGRPASAWSVQRIGLLQSKIERYTYNIYHNNKYGKHNLSKLIPGHALIQFANETFGYDGWRMDVIDVEARECQPFTAVNNGENTNTSEVKYTVVAEAQVKVTLKDGTNTQCGGLGRITLSSRGECYNRSKKEAVGDALKKALLSFEKIILDYETKITNNYYVDGLYGSKKIKNEANTNYNLLSATNSKPTFIKLEDAKGTHIK
What is the function of this protein?
Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing.  Anneals complementary single-stranded DNA.
What are the official names of this protein?
DNA repair protein RAD59.
What is the protein family that this protein belongs to?
Belongs to the RAD52 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_METKA
Sequence: MGAGEMAEALGEELEREIQRRWEEMDLLSKVLEKNRDGPLFYFLDGPPYASGSIHLGTAWNKIIKDAVNRYKLMRGYRVRLQPGWDCHGLPIEVKVEQEVLSDEIECKKDIEEKVGVDKFVEKCKEFALKHVEIMTEQFKRLGVLMDWDNPYMTLDNEYIEGAWYTLKRAHERGLLDRDVRIVNWCPRCETALADHEVEYKEVEDPSIFVIFPIEDDSDAEVDLPENSALLIWTTTPWTLPANLAVAVHPEEEYVLARAEVDGEEWHLIVADKLKVVLSVVTDSYEIVDSFPGEALEGLRYRPPLWEEVPKLRELHEEDDRVHRVYTAEWVTMEEGTGCVHSAPGHGEEDFELGREVGLPPHCPVAEDGTFTEDGGKYEGLYVRDANEKIVEDLREKGLLAHEDTVEHRYGHCWRCKTPIIYRATEQWFLKVTEVKDEMLEWIERVEWIPEWAGHSRFKSWVENARDWCISRQRYWGIPLPVWECEECGHLEVIGSLSELEAKAVSLPPGEPDLHRPWVDEVVLKCPECGSYMRRVPDVLDVWVDSGVAAWASLGYPRREDEFERWFLKEGRCDPDDPEAGADFITEGHDQTRGWFYSQLGCGVVTFDTCPYRTVLMHGFTLDEEGRKMSKSLGNVVDPMDVVEKYGADTLRWYVLRSNAPWRDMHFSWQDVRDTHRALNVLWNAYRFTKMYSELDEFDPEEHPLEDLEEHLKPEDRWLLSRINSLVEEVTDAFERYHVHEAARALYRFVTEDLSRWYIRLVRERVWLEGDDPEKLAVYAVLHYTFDRLVRLLAPIVPHVAERIYLDYVRAGDDPESVHLTDWPEVDDRWVDEGLEKAMELVRKAAEAALSVRQRAGVKTRWPLRRLFVEVEDPKRLEDLKDVLARVANVKEVELGEEFPEKVPVAEPRPDKIGPEFRSLAGRVIEHVKDRAEEVARSILKDGEYRTELDGEDVVLTEEHVKVTEDLPEGWEAEEFEGGRVYVFVELDEELKSEAWAREVVRRVQEMRKELDLNLEERIRVWIETDEEIAEAVEEHSEYVRGETRADELHVNEGWPEEVDLEREWEVEDRTIRIAVVVSG
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRH2_PONPY
Sequence: MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
What is the function of this protein?
The H2 subclass of histamine receptors mediates gastric acid secretion.  Also appears to regulate gastrointestinal motility and intestinal secretion.  Possible role in regulating cell growth and differentiation.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).
What are the official names of this protein?
Histamine H2 receptor, H2R, HH2R, Gastric receptor I.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPR58_ARATH
Sequence: MASHLFTRSRISLLKTLKPNPFTSASPIRAISGTPFLSQDPLLATESTDHDPSNHQSTSTPLPPNPATGSPLYQENWRSPIPNTPSFNQSLVPLGFLNQAPAPRIRALSETLDMNSLLNMFADWTASQRWSDMKQLFEVWVRSLDKNGKPNKPDVNLYNHYLRANLMMGASAGDMLDLVAPMEEFSVEPNTASYNLVLKAMYQARETEAAMKLLERMLLLGKDSLPDDESYDLVIGMHFGVGKNDEAMKVMDTALKSGYMLSTSVFTECVRSCVAKGRTDTLVSIIERCKAVDRNKSLCPSWILCNYIAEVAIQEDNSKLAFYAFEFMFKWITRGEMARPSVIFSVDEGLVVAGLASAARTCSSSLVEGSWTILKQSLRGRKAANPASYIAKINAYASLGNLQKAFTSLHELESAYADSEKEVVEEMLSPFTSLYPLVVACSKKGFETLDEVYFQLESLSQGDTPYKSVAALNCIILGCANTWDLDRAYQTFEAISASFGLTPNIDSYNALLYAFGKVKKTFEATNVFEHLVSIGVKPDSRTYSLLVDAHLINRDPKSALTVVDDMIKAGFEPSRETLKKLRRRCVREMDDENDDQVEALAKKFQIRMGSENRRNMLFNIDYSRGRALNN
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g26460, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: S10AG_MOUSE
Sequence: MADCYTELEKAVVVLVENFYKYVSKHSLVKNKISKSSFRKMLQRELNHMLTDTGNRKAADKLIQNLDANHDGRICFDEYWTMIGGITSPMANLIRQQECQQESQQECQQESQQESQQESQQGSS
What is the function of this protein?
Calcium-binding protein.  Binds one calcium ion per monomer (PubMed:17030513).  Can promote differentiation of adipocytes (in vitro).  Overexpression in 3T3-L1 preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake (PubMed:21266506, PubMed:23526364).
What are the official names of this protein?
Protein S100-A16, Protein S100F, S100 calcium binding protein A16.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Note=Primarily nucleolar. A high intracellular calcium level induces nucleolar exit and nucleocytoplasmic transport, whereas a low intracellular calcium level leads to nuclear translocation and accumulation within specific region of nucleoli (PubMed:17030513).
Protein: SECA_SACEN
Sequence: MVLSRLLRAGEGKLLKRLRRIAAHINELEDDVLALSDAELRAKTDEFKRRHTDGESLDELLPEAFAVAREGARRTLGQRHFDVQLMGGAALHLGQIAEMKTGEGKTLTCVLPAYLNAIAGRGVHVVTVNDYLAKRDADWMGRVHRFLGLEVGAIMADMTPEQRRHAYAADITYGTNNEFGFDYLRDNMAWSLADCVQRGHFFSIVDEVDSILIDEARTPLIISGPADQSSRWYQEFARLAPMLKKDQHYEVDERKRTVGVTEDGVTIIEDQLGIENLYEAANTPLVGYLNNALKAKELYKRDKDYIVRNGEVVIVDEFTGRILHGRRYNEGMHQAIEAKEGVEIKAENQTLATITLQNYFRLYEKLAGMTGTAETEAAEFNGTYKLGVVPIPTNRPMARADQPDLVYKSEVAKFEAVAEDIEEKHRKGQPVLVGTTSVERSEYLAKLLVKKGVPHNVLNAKYHQSEAAIIAEAGRKGAVTVATNMAGRGTDIVLGGNVDHLADAELRKRGLDPVDNREEYEAQWPAVVEKIKEQVEAEAEEVRELGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDELMRRFNAAMVETVMTRLKVPDDVPIEHKMVTRAIRSAQTQVEQQNMEIRKNVLKYDEVMNQQRSVIYDERRRVLEGEDLQEQVRHMIRDVVTEYVNAATADGYAEDWDFEKLWSALKTLYPVSVSWEALVDSDEDLSKERLLEEVLADAEAAYAKREAEVDGKVGPGAMRELERRVVLSVLDRKWREHLYEMDYLKEGIGLRAMAQRDPLVEYRREGFDMFHAMLDALKEESVGFLFNVQVEAAEPEPAPEQPSVPVSVSRSAEPTPDLQAAAEAAAAQSQVRRAKPTSAGPALSQLPGSTTQAPSALRGKGLDAPEKQRLNYSGPTEQGGVQTTSESAGEQGNGTSTRRERRAAARAEAKKNKRR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RF3_XANC8
Sequence: MSEVSNEAARRRTFAIISHPDAGKTTLTEKLLLFGGAIQMAGSVKGRKAARHATSDWMALEKERGISVTSSVMQFPYEDKIVNLLDTPGHADFGEDTYRVLTAVDSALMVIDVAKGVEERTIKLMEVCRLRDTPIMTFINKLDREGKNPIDLLDEVETVLGIQCAPVTWPIGMGQRLKGVVHLITGEVHLYEQGRNFTRQDSTIFPSLDAPGLAEKIGTQMLDELREELELVQGASNPFDLDAYRAGQQTPVFFGSGVNNFGVQPLLDFFVEHAPPPQARDTTGRRVEAVEPKLSGFVFKIQANMDPQHRDRVAFMRVCSGKFTAGMKALHVRSGKDVKLANALTFMASDREIAAEAWPGDVIGIHNHGTISIGDTFTEGESLSFTGIPNFAPELFRRARLRDPLKLKQLQKGLAQLSEEGATQFFRPLMSNDLILGAVGVLQFDVVAYRLKDEYGVDAIFEPVSVTTARWVHCDNPKKLEEFREKNAGNLGIDAAGQLVYLAPTRVNLQLAQERAPDVRFSATREHAYATAVD
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZC21A_PONAB
Sequence: MEGLEENGGVVQVGELLPCKICGRTFFPVALKKHGPICKKTATKKRKTFDSSRQRAEGTDIPTVKPLKPRPEPPKKPSNWRRKHEEFIATIRAAKGLDQALKEGGKLPPPPPPSYDPDYIQCPYCQRRFNENAADRHINFCKEQAARISNKGKFSTDTKGKPTSRTQYKPPALKKSNSPGTASSGSSRLPQPSGAGKTVVGVPSGKVSSSSSSLGNKLQTLSPSHKGIAAPHAVANVKPRNSTPPSLARNPAPGVLTNKRKTYTESYIYRPDGDSASSLNGGNIKGIEGNSPGNLSKFCHECGTKYPVEWAKFCCECGIRRMIL
What are the official names of this protein?
Zinc finger C2HC domain-containing protein 1A.
What is the protein family that this protein belongs to?
Belongs to the ZC2HC1 family.
Protein: CLPX_RHILW
Sequence: MSKVSGSNGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSRDGVPTPQDIIKVLDEYVIGQRQAKKILSVAVHNHYKRLAHASKNGEVELAKSNIMLVGPTGCGKTYLAQTLARIIDVPFTMADATTLTEAGYVGEDVENIILKLLQSADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDKIISARGEKTSIGFGATVKAQDDRRVGEVLRELEPEDLVKFGLIPEFIGRLPVLATLEDLDEDALIQILSEPKNALIKQYQRLFEMEDVELTFHEDALREIARKAIVRKTGARGLRSIMEKILLDTMFELPTLEGVREVVISEEVVRGSARPLYIYADRQEEKANASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: NHAA2_PSE14
Sequence: MHNPTPRTESPSALAFIKRFFAAEAAGGLILMAAALAALIVANSPLADSYFAALHTVLAGMSVEHWINDGLMAIFFMLVGLEIKREMLAGQLASWSQRALPGFAALGGMVVPALIYVAFNWGQPDTIGGWAIPAATDIAFALGVLSLLGKRVPLSLKIFLSALAILDDLGAVLIIALFYTSDLSIPMLLAALGSIAVLVALNRLSVKKLLPYLIVGALLWFFMLQSGIHATLAGVALALCIPLGKPDEEASSPLLHLEEKLHPWVAFAVVPVFGFANAGVSLSGITVDKLLDPVPLGVALGLLIGKQVGIFALAALAIRAGLARLPDGSNWGQLYGVAALCGIGFTMSLFIGALAFPGAPELVDEVKVGVLIGSVLSALLGVVVLRRFGARG
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.