PharMolix/UniProtQA huggingface dataset:
Protein: GR64C_DROME
Sequence: MQQSGQKGTRNTLQHAIGPVLVIAQFFGVLPVAGVWPSCRPERVRFRWISLSLLAALILFVFSIVDCALSSKVVFDHGLKIYTIGSLSFSVICIFCFGVFLLLSRRWPYIIRRTAECEQIFLEPEYDCSYGRGYSSRLRLWGVCMLVAALCEHSTYVGSALYNNHLAIVECKLDANFWQNYFQRERQQLFLIMHFTAWWIPFIEWTTLSMTFVWNFVDIFLILICRGMQMRFQQMHWRIRQHVRQQMPNEFWQRIRCDLLDLSDLLGIYDKELSGLIVLSCAHNMYFVCVQIYHSFQSKGNYADELYFWFCLSYVIIRVLNMMFAASSIPQEAKEISYTLYEIPTEFWCVELRRLNEIFLSDHFALSGKGYFLLTRRLIFAMAATLMVYELVLINQMAGSEVQKSFCEGGVGSSKSIFS
What is the function of this protein?
One of the few identified sugar gustatory receptors identified so far and which promotes the starvation-induced increase of feeding motivation.
What are the official names of this protein?
Gustatory receptor for sugar taste 64c.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr5a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: N7BML_YARLI
Sequence: MIPTPVLRFNPIADKVPKWKRIYHKWRGIQNMPFKSKYFVGYDLDGNSYWEFKNVNNPGRYRRIVEPAKPDLSLVDHKIPPQWVQWLRFTRPHHPTLEELIADKQRQELLQAKIAAYEAKWKEIPLKTAENADESRDMSLEDQLKPTFTEAELAEMAQVFEKVPQQAAPAPPRVPNMAAIEVEDIIKHYPENGPDTVLADGGRQRDHDLKMDYVEKERDDSGKPAEWTPKAAVRRRG
What is the function of this protein?
Acts as an assembly factor of mitochondrial complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase assembly factor N7BML, N7BM-like protein, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 homolog, NDUFAF2 homolog.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA12 subunit family.
Protein: DCLK_DROSI
Sequence: MELEKVKINSLHCNDAVLSSLQASPSATHPQSVPSKANAVTEASIIEKTNLQHNVQEDNSYNRDCDSPVSSSSEPEKELDDLRYLHSSSLTNSVVVGKSTGSLNGAYSITSVTSKTKTLEPNSASGSACLTIAPTADHIKKRIPSSRTPTRKALRIKFYRNGDRFYPGITIPVSNERYRSFERLFEDLTRLLEENVKIPGAVRTIYNMCGKKITSLDELEDGQSYVCSCNNENFKKVEYNTGSQPLSNLTLTSSRSNSHRLDKCRPSSPLKNGLLAGSSPLPTCGGGTGNGSPHIASRSSDRVTVVHPRIVTLIRSGTKPRRIMRLLLNKRNSPSFDHVLTAITQVVRLDTGYVRKVFTLSGVSVVRLSDFFGSDDVFFAYGTERINTAEDFKLEAEEHRAINVIRKTMRTTGTTCKGPKPKMPIKSKKVYPPVVDSEAFKAATTPEDDSHAALLTSTGMEINELPSNIRNTYTLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTRFSESQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGHVLELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHPWTIGNQNECTTYKR
What are the official names of this protein?
Serine/threonine-protein kinase GD17699, Doublecortin-like and CAM kinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: MDH_NOCSJ
Sequence: MSSTPLKVAVTGAAGQIGYSLLFRLASGSLLGDRPIELRLLEITPALKALEGVVMELDDCAFPNLAGVQIGDDAEQIFDGVNLALLVGARPRGPGMERGDLLSANGAIFTAQGKALNKVAADDVRIGVTGNPANTNALIAMTNAPDIPQARFSALTRLDHNRAISQLAAKTGAAVTDIKKMTIWGNHSATQYPDVFHAEIGGRNAAEVVGDQDWIESTFIPTVAKRGAAIIEARGSSSAASAASATIDAARDWLFGSADADWVSMAVVSDGSYGVPEGLISSFPVTTKDGDWEIVQGLEIDDFSRAKIDASTAELADEREAVKELGLI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: SSRP_GLUDA
Sequence: MISTGIAAQNRKGRFNYTILETLEAGMVLKGPEVKSLRLGRATINEAYAGDRDGEIWLFNSYIPEYQGGVLSRFETRAPRKLLLHRKQVDKLLGAVARDGVTLVPLDIHFNARGVAKVTLGIGEGRKKADKRQAIADRDWQRDKARLLRNKGRE
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: KYNU_BACHK
Sequence: MYKEPFQPTYEYALECDKHDELKDFQTEFYKKEGTIYLDGNSLGLLSKRAEKSLLTLLDSWKEYGIDGWTEGEHPWFFLSEKLGELTAPLIGALPEESIVTGSTTTNIHQVIATFYEPKGIRTKILADELTFPSDIYALQSQIRLKGLDPDEHLVRVKSRDGRTLSEDDIIQAMTDDIALILLPSVLYRSGQILDMKRLTAEAHERGIHIGFDLCHSIGSIPHHFKEWDVDFAIWCNYKYLNAGPGGVAGLYVNKKHFNRLPGLSGWFSSRKDKQFDMEHTLTAADHAGAYQIGTPHILSTAPLIGSLEIFKDAGIERLREKSLHITRYMLNLIDHELKDFGFAIGNPLEDEKRGGHIYLEHAEAARICKALKANGVIPDFRAPNGVRLAPVALYNTYEEVWQSVMILKKIMKDEEYKQFENKREVVA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: ENOA_RAT
Sequence: MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTDQVVIGMDVAASEFYRAGKYDLDFKSPDDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWDAWQKFTATAGIQVVGDDLTVTNPKRIAKAAGEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK
What is the function of this protein?
Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate.  In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses.  May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons.  Stimulates immunoglobulin production.
What are the official names of this protein?
Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 1, Non-neural enolase, NNE.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.
Protein: ATP6_ALKAL
Sequence: EEFANTLTLGMRLFGNVYAKEMLMILLVGLGTSGFLGAFGAFLPLIVWQAFGMFIGSLQAFIFAMLAMVYMAHKVEAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y346_STRTD
Sequence: MKNNSIRTVVATGIGAALFIIIGMFVNIPIFGNTSIQLQYAVQALFSVIFGPITGFFMGFIGHALKDGIQYGNISWAWVLASGITGLVIGLFGKKYDVTMGKFSVMSMIWFNLAQALGLLIGYGVVTPIGDKIQFAQAWSYLYAQSFVAGVANFITIAIGGTLLLAIYASSRTQSGSLTKD
What are the official names of this protein?
UPF0397 protein STER_0346.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFA_MYCVP
Sequence: MAEQPVDLSDEALAQAVSAASRAFDQASTLDELAKAKTEHLGDRSPIALARQALGSLPKTDRADAGKRVNVARTQAQAGYDDRLAALRAERDAEVLVAERIDVTLPSTRQPVGARHPITILAENVADTFVAMGWELAEGPEVETEQFNFDALNFPPDHPARSEQDTFHIAPDGSRQVLRTHTSPVQVRTLLERELPVYVISIGRTFRTDELDATHTPVFHQVEGLAVDKGLTMAHLRGTLDAFARAQFGPQGRTRFRPHFFPFTEPSAEVDIWFPNKKGGPGWVEWGGCGMVNPNVLRACGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLPFGVGA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_BURVG
Sequence: MKLSFTKMHGAGNDFVVLDGYSHTLPPLTDVQVRALADRHFGIGADQLLVVEKPTVDGADFKYRIFNCDGGEVEHCGNGARCFVKFVTDRGLTDKRSVRVQVMKGLITLTMQDNGEVVVDMGAPVFEPAQVPFDASGLDGRTDGNDTLWPLDVGGATRWVSTVSMGNPHAVQVVDDAEAYPVLAEGPLIERHARFPKRVNAGFMQIVSRHEVKLRVYERGAGETLACGTGACAAVAAGIRRGLLDTPVTVHTHGGTLTISWDGAHDERAALTMAGPATTVFEGEIELNV
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_MYCTO
Sequence: MTTVLGIETSCDETGVGIARLDPDGTVTLLADEVASSVDEHVRFGGVVPEIASRAHLEALGPAMRRALAAAGLKQPDIVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGGHTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPGGKALDDLARTGDRDAIVFPRGMSGPADDRYAFSFSGLKTAVARYVESHAADPGFRTADIAAGFQEAVADVLTMKAVRAATALGVSTLLIAGGVAANSRLRELATQRCGEAGRTLRIPSPRLCTDNGAMIAAFAAQLVAAGAPPSPLDVPSDPGLPVMQGQVR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_TROWT
Sequence: MHERHIGPSQEEIDHMLGFLGYKSLDDLMNAALPNGVQSPPDIKIPSHDELTCLTQLAAYAKMNRIKTSMLGQGFYNCITPAVIRRNILENPSWYTSYTPYQPEISQGRLEMLINFQTMICDLTGLEIANASMLDEASCAAEAMLLAKRVSRSSSNKYLVHNGVFPHIRRVLETRADAVGVEIVDLPEGQSIDFDHFGVYAQYQSASGKLLDLRHLFSRSKRAGAICVIGCDLLMLTLFTSPGELGADIAFGSAQRFGIPMNFGGPLASFLAARKAMERSLPGRLVGVSVDADSNHAYRLTLQTREQHIRREKATSNICTATVLMAIAAVAFAQHHGPKGLRAIAHRINTVAVGFARLLKQTAFRVSSLDIFDTIEINNPTQLCVEAESKHDLLFWKVDDNKLRITFDEVTARLDGDLPERLSKVFGISPDKIRDLGCNYDSCDCSFYSDSQQAREGLSSVASRNISVHSDLARHPLRRFSGYLKHPVFNNYTGEVALMRYLKALSDKDFALDRGMIPLGSCTMKLNAAFQLEPVLWPEFANLHPFAPRGDADGTLQIIDQIETWLANLSGYDAVSLQPTAGSQGELAGLLAIRGYYKSLNLDRDVCLIPASAHGTNAASAVLAGMRVVVVACDQQGNIDLDDLRLKASKNAHALAALMVTYPSTHGVYEDNISEVCSVVHKYGGQVYVDGANSNALIGYLRTGDFGGDVSHLNLHKTFGIPHGGGGPGIGPVVAKAHLAPFLPFRNRVHKPSTDLPAVKHMGGPIASSDYGFAGALYISWAYIFCLGSQGMKRCTAVAVLVANYIAKQLSDTFPVLYTGKNNLVAHEFIMDFREVTRVSGITVDDVCKRLIDYGFHAPTMSFPVPGTLMVEPTESEPFSEIQRFIKTIRSIRAEIDRVIDKTYDPDNNPLKRAPHTLEQIASDKWDRPYSRRTGIVYTSGKYWPASARIDNAYGDRNIFCTCPDLPD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: TOLB_CAMJR
Sequence: MKKIVAIFLVFLGSLWAEDPVIDVVNSGVVLPKIIVKDNSNLSDENLKKSFYNIIVNDLKVSSNFEVVANATETSNYTFEYTLNKNGNTLSLNVKIKAGGSDKSEQTYTLNGLEQYPFLAHKSVKASVNALGLAPVDWMDHKILIARNSSSKKSQIIMADYTLTYQKVIVDGGLNLFPKWGNKEQTLFYYTAYDHDKPTLYRYDLNTNKASKILSSGGMVVASDVSVDGSKLLVTMAPKDQPDVYLYDLNTKNLTQLTNYSGIDVNGNFIGSDDSKVVFVSDRLGYPNIFMQDLNSNSAEQVVFHGRNNSAVSTYKDFLVYSSREPNQAGVFNIYLMSINSDYIRQLTANGKNLFPRFSSDGGSIVFIKYLGAQSALGVIRVNANKTFYFPLRVGKIQSIDW
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RAPZ_ECOL5
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: Y1032_PSEMY
Sequence: MLMVISPAKTLDYETPPATPRFTQPEHLDHAQELIAQLRDFSPAQIAELMHLSDKLAGLNAARFGSWERPFNPSNAKQALLAFKGDVYTGLHAEDFSEDDFDFAQAHLRMLSGLYGVLRPLDLMQPYRLEMGTKLVNGRGKDLYAFWGERISAWLNQALAAQGDDVLLNLASNEYFGAVKRKALNARIIDTEFKDLKNGQYKIISFYAKKARGLMARYVIKERLTNPEGLKDFNYQGYRYSAEHSKADSLVFLRDQPLD
What are the official names of this protein?
UPF0246 protein Pmen_1032.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: EST5A_FELCA
Sequence: MSGMWVHPGRTLIWALWVLAAVIKGPAADAPVRSTRLGWVRGKQTTVLGSTVPVNMFLGIPYAAPPLGPLRFKQPKPALPGNDFRNATSYPKLCFQDLEWLVSYQHVLKVRYPKLEASEDCLYLNIYAPAHADNGSNLPVMVWFPGGAFKMGSASSFDGSALAAYEDVLIVTTQYRLGIFGFFDTGDEHARGNWALLDQVAALTWVRDNIEFFGGDPRSVTIFGESAGAISVSSLILSPIANGLFHKAIMESGVAILPLLMRPPGDERKKDLQVLARICGCHASDSAALLQCLRAKPSEELMDISKKLTFSIPVIDDFFFPDEPVALLTQKAFNSVPSIIGVNNHECAFLLSTEFSEILGGSNRSLALYLVHTFLNIPTQYLHLVADHYFYNKHSPVEIRDSFLDLLGDVLFVVPGVVTARYHRDAGAPVYFYEFQHPPQCLNDTRPAFVKADHSDEIRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMRYWANFARTGDPNGEGVPLWPAYTQSEQYLKLDLSVSVGQKLKEQEVEFWMNTIVP
What is the function of this protein?
Carboxylesterase present at high level in urine that regulates production of felinine, a probable pheromone precursor.  Probably acts by hydrolyzing the peptide bond of the felinine precursor 3-methylbutanol cyteinylglycine, producing felinine and glycine in cat urine.
What are the official names of this protein?
Carboxylesterase 5A, Carboxylesterase-like urinary excreted protein, Cauxin.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVD_GLAP5
Sequence: MPKLRSATSTQGRNMAGARALWRATGMKENDFGKPIIAVVNSFTQFVPGHVHLKDMGQLVAEQIEKAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVNAHCADAMVCISNCDKITPGMLMAALRLNIPTIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGANPNVSDEVSDQIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSCLATHADRKQLFLDAGTQIVELCKKYYEQDDLSVLPRSIATKAAFDNAMSLDIAMGGSTNTVLHLLAAAQEAEVDFTMADIDRLSRQVPCLSKVAPNTQKYHMEDVHRAGGIMAILGELDRAGLLNNQTRTVLGLSLAEQIAKYDIMLTKDEAVHKFFRAGPAGIRTTKAFSQDTRWDTVDDDRQNGCIRSKEFAYSQDGGLAMLSGNIALDGCIVKTAGVDEAILKFKGEAIVFESQEDAVAGILGGKVRAGHVVVIRYEGPKGGPGMQEMLYPTSYLKSMGLGKACALLTDGRFSGGTSGLSIGHCSPEAAAGGLIGLVKDGDTIEIDIPNRKIELVVPEAELAQRRAEQDAKGWKPANREREVSFALKVYGHFATSADKGAVRDKSKI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: DNAK_SHEHH
Sequence: MGRIIGIDLGTTNSCVAVLDGGKARVLENAEGDRTTPSIIAYTADETLVGQSAKRQAVTNPTNTVYAIKRLIGRRFKDDEVQRDVDIMPFKIISADNGDAWVEAQGKKMAPPQISAEILKKMKKTAEDFLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAYGIDKKQGDNIVAVYDLGGGTFDISIIEIDSVDGEQTFEVLATNGDTHLGGEDFDNRMIKYLADEFKKEQGLDLRNDPLAMQRLKEAAEKAKIELSSTTQTEVNLPYITADATGPKHLVVKITRAKLESLVEDLIKRSLEPLKVALADADLSVSDINEVILVGGQTRMPKVREEVSAFFGKELRQDVNPDEAVAIGAAVQAGVLSGDVKDVLLLDVTPLSLGIETMGSVMTKLIEKNTTIPTKASQTFSTADDNQSAVTIHVLQGERKQSSGNKSLGQFNLEGIEAAPRGMPQIEVAFDIDADGILHVSATDKKTGKAQNITIKASSGLSDEEVEAMIRDAEAHADEDAKFEELVKSRNQADGMVHATKKQIEEAGEALPADEKEKIEAAMANVETAVKGNDKEAIEKSTQELMEASSKLMEIAQAKAQAEQGQPEGEAKSAKPEDDVVDAEFEEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ISPH_YERPP
Sequence: MQILLANPRGFCAGVDRAISIVERAIEMYGAPIYVRHEVVHNRYVVESLCERGAIFIEEISEVPDGSILIFSAHGVSQAVRAEARSRNLTMLFDATCPLVTKVHMEVARASRKGKEAILIGHAGHPEVEGTMGQYSNPNGGMYLVESPDDVWQLNVKDENNLCFMTQTTLSVDDTSAVIDALNTRFPKIVGPRKDDICYATTNRQEAVRNLANDADIVLVVGSKNSSNSNRLAELVQRMGKPAYLIDSAADIQEFWLQGAKCIGVTAGASAPDILVQQVIARLKDLGAGESIELSGREENIVFEVPKELRVEVKQID
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: ASE2_ARATH
Sequence: MAATSSISSSLSLNAKPNKLSNNNNNNKPHRFLRNPFLNPSSSSFSPLPASISSSSSSPSFPLRVSNPLTLLAADNDDYDEKPREECGVVGIYGDSEASRLCYLALHALQHRGQEGAGIVTVSKDKVLQTITGVGLVSEVFSESKLDQLPGDIAIGHVRYSTAGSSMLKNVQPFVAGYRFGSVGVAHNGNLVNYTKLRADLEENGSIFNTSSDTEVVLHLIAISKARPFFMRIVDACEKLQGAYSMVFVTEDKLVAVRDPHGFRPLVMGRRSNGAVVFASETCALDLIEATYEREVYPGEVLVVDKDGVKCQCLMPHPEPKQCIFEHIYFSLPNSIVFGRSVYESRHVFGEILATESPVDCDVVIAVPDSGVVAALGYAAKAGVAFQQGLIRSHYVGRTFIEPSQKIRDFGVKLKLSPVRGVLEGKRVVVVDDSIVRGTTSSKIVRLLREAGAKEVHMRIASPPIIASCYYGVDTPSSNELISNRMSVDEIRDYIGCDSLAFLSFETLKKHLGEDSRSFCYACFTGDYPVKPTEDKVKRGGDFIDDGLVGGIHNIEGGWVR
What is the function of this protein?
Catalyzes the first committed step of 'de novo purine biosynthesis from glutamine.  Required for chloroplast biogenesis and cell division.  Confers sensitivity to the phenyltriazole acetic acid compound [5-(4-chlorophenyl)-1-isopropyl-1H-[1,2,4]triazol-3-yl]-acetic acid (DAS734), a bleaching herbicide.
What are the official names of this protein?
Amidophosphoribosyltransferase 2, chloroplastic, AtATase2, AtPURF2, PRPP2, Glutamine phosphoribosylpyrophosphate amidotransferase 2, AtGPRAT2, Protein CHLOROPLAST IMPORT APPARATUS 1, Protein DIFFERENTIAL DEVELOPMENT OF VASCULAR ASSOCIATED CELLS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: MBCA_MYCTO
Sequence: MGVNVLASTVSGAIERLGLTYEEVGDIVDASPRSVARWTAGQVVPQRLNKQRLIELAYVADALAEVLPRDQANVWMFSPNRLLEHRKPADLVRDGEYQRVLALIDAMAEGVFV
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Neutralizes the activity of cognate toxin MbcT by blocking access to the toxin active site.
What are the official names of this protein?
Mycobacterial cidal antitoxin MbcA.
What is the protein family that this protein belongs to?
Belongs to the MbcA/ParS/Xre antitoxin family.
Protein: FGL1_MESAU
Sequence: MGEIRSFLLVTIALMMGREIWALENSKCLLEQERLRAQVQQLETRVKQQQARIAQLMHEKEVQLLDKGQEDNFFDLGGKRQYADCSEIYNDGFKQSGFYKIKPHQSQAIFSVYCDMSDGGGWTVIQRRSDGRENFNRCWNDYENGFGNFVQNNGEYWLGNKNINLLTMQGDYTLKIDLTDFEKNSRFAQYKHFKVGDKKSFYELNFGEYSGTAGDSLSGTYHPEMQWWASHQRMKFSTRDRDNDNYKGNCAEEEQSGWWFNRCHSANLNGVYYQGPYTAETDNGVVWYTWHGWWYSLKSVVMKIRPNDFIPNVI
What is the function of this protein?
Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3.  Responsible for LAG3 T-cell inhibitory function.  Binds LAG3 independently from MHC class II (MHC-II).  Secreted by, and promotes growth of, hepatocytes.
What are the official names of this protein?
Fibrinogen-like protein 1.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the blood plasma.
Protein: PRMA_ALKMQ
Sequence: MKWIEVSIKTTSEAVEAVANILYDGGVAGVSIEDENDFSLLEQSNEAWDYVDEALLDRELEGALVKGYLPEAADLAYKLELIRQSVALLPKYGLNIGLGEVTTLEVNEEDWSHSWKKYYKPTHIGKNIVVKPTWEEYERKEGEMIIEMDPGMAFGTGTHETTMMCAQELEKIVGAKYTVFDIGCGSGILSIVAAKLGAEKVIAVDLDGTAIRVTQENVDANDVSDIVEVRHGNLMDVVTSRADVIVANIIADIIILLSKDVKNFLKKEGIFIASGIILDKVEVVKAQLIANNLEIVKVETMGEWAVIISKLKGGVDE
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_STRPG
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAYVRNEIASENYDEVTDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: UGA2_YEAST
Sequence: MTLSKYSKPTLNDPNLFRESGYIDGKWVKGTDEVFEVVDPASGEIIARVPEQPVSVVEEAIDVAYETFKTYKNTTPRERAKWLRNMYNLMLENLDDLATIITLENGKALGEAKGEIKYAASYFEWYAEEAPRLYGATIQPLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALAMAYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGKILMKQSSSTLKKLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAKLLAERVKKFVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELGPNFYAPVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVFSKNVNTLYTVSEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTITIGNLPNSI
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase [NADP(+)], SSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: RL14_SOLUE
Sequence: MIGMRTILEVADNSGARRLSCILPRGGDLGLRAGLGDVVTAAVKEAAPDSAIKKGKVVRCVIVRMRKETRRKDGTYIRFDSNAAVLINDVGEPVGTRVFGPVARELRDKKFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.