PharMolix/UniProtQA huggingface dataset:
Protein: UXUA_THEMA
Sequence: MKLVFRWYGEKHDTVTLEQIRQIPGVEGVVGALFDIPVGEVWPFEEIMKLKETVEKAGLKLEVIESVNVHEDIKLGLPTRDRYIENYKKTIRNLAKAGVKVVCYNFMPVFDWMRTDLHKKLPDGSETMEYDHRLIEGVTPDELIKRVKEGSQGFVLPGWEWDRLEKLRETFELYKNVDEEKLFENLVYFLERVIPVCEECDVKLAIHPDDPPWSIFGLPRIITNKENIERMLKAVDSPYNGITFCMGSLGANPENNIPEMIRYFGKMGRIHFAHVRNLKFTGEKSFYETAHPSFCGSHDLFEVMKAFHDIGYEGYIRPDHGRLIWGEKARPGYGLYDRALGATYILGLWEAIDKMKKRYC
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: RS12_LACDA
Sequence: MPTINQLVRKGRHSKTTKSKSPALNYSYNSMKKEQVFNPAPQMRGVATRVGTMTPKKPNSALRKYARVRLSNLTEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVDGRKQARSKYGAKKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: HPRT_PIG
Sequence: MATRSPSVVISDDEPGYDLDLFCIPNHYAEDLEKVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVKQHNPKMVKVASLLVKRTPRSVGYRPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
What is the function of this protein?
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate.  Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX150_BUNCI
Sequence: DQGTACTGEHAHNFCLNGGTCRHIQSLGEYYCICPEGYTGHRCEK
What is the function of this protein?
Has both toxic and EGF activity.
What are the official names of this protein?
Toxin Bcs III 15.09.
What is the protein family that this protein belongs to?
Belongs to the EGF domain peptide family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: NOG2_PNECA
Sequence: MCCKAIKLGNARVFPVTTFRDAKKVRWINLLKSGKAKRNKSGKIIKQGEFQSKDVQDARIQPYRRWFSNTRVISQDVLNMFRESFAEKLNDPCKVLLKQNKLPMSLLMEPTKTRKANIIDIEPFDDTFGKKSXRKRAKLYASSIENLSNFAFESYENYIKKNSEYENVDKNIQKSFEAIFSKGTSKRIWNELYKXIDSSDVIIQLLDARNPLGTRCKHVEEYLKKEKPHKHMILLLNKCDLIPTWCTREWIKQLSKEYPTLAFHASINNPFGKGSLIQLLRQFSKLHSNRRQISVGFIGYPNTGKSSVINTLRSKKVCNTAPIPGETKVWQYVRMTSKIFMIDCPGIVPPNSNDSETEIIIKGALRIEKVSNPEQYIHAILNLCETKHLERTYQISGWENDSTKFIELLARKTGKLLKGGEVDESSIAKMVINDFIRGKIPWFIAPAQENDPSNIKLSNNTLVEKNHLTTLDDEIYNDANPNA
What is the function of this protein?
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
What are the official names of this protein?
Nucleolar GTP-binding protein 2, Binding-inducible GTPase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: 34KD_MYCTU
Sequence: MTYSPGNPGYPQAQPAGSYGGVTPSFAHADEGASKLPMYLNIAVAVLGLAAYFASFGPMFTLSTELGGGDGAVSGDTGLPVGVALLAALLAGVALVPKAKSHVTVVAVLGVLGVFLMVSATFNKPSAYSTGWALWVVLAFIVFQAVAAVLALLVETGAITAPAPRPKFDPYGQYGRYGQYGQYGVQPGGYYGQQGAQQAAGLQSPGPQQSPQPPGYGSQYGGYSSSPSQSGSGYTAQPPAQPPAQSGSQQSHQGPSTPPTGFPSFSPPPPVSAGTGSQAGSAPVNYSNPSGGEQSSSPGGAPV
What are the official names of this protein?
34 kDa antigenic protein homolog.
What is the protein family that this protein belongs to?
To M.paratuberculosis 34 kDa antigenic protein.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMD_VIBVY
Sequence: MWVGVISLFPEMFRSVTDFGVTGQAVKKGLLSIETWNPRDFTHDKHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKQASPGKTKVIYLSPQGRKLDQQGVEELATNENLLLICGRYEGVDERIIQSEVDEEWSIGDFVMTGGEIPAMTLIDSVSRFVPGVLGDFASAEEDSFANGLLDCPHYTRPEVLDGKEVPEVLMSGNHKEIRRWRLKQSLGRTWQRRPELLENLALTDEQEQLLAEFIQETHHKRK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPL_BPPM2
Sequence: MFSTLAKYLAVKLLTETFIKRVCLATAKHLANKSENTLDNELIDALEDALN
What are the official names of this protein?
Uncharacterized protein Gp-l.
Protein: RNH2_CLOB8
Sequence: MIQFNEDIRSLSFAEIKEEIHKLSIVDLYRNDEHTKLINWLEEDKRKNVLSLKEKIEKDLESYLNEVKRVKTMYEFDKSFGSYRYIAGVDEVGRGPLAGPIVACSVILDLNVLEKDLILYINDSKKVKEHKREELSEIIKEKALSYQIAVSSNKEIDEKGIAFANNKVFLESCNSLSIKPDLVLSDGYLIKNIGIENKSVIKGDTKSASIAAASIVAKVYRDRLMKEYAKKYPHYDFENNVGYGTSKHIEGLKKYGKSDIHRNSFLTKLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEI3B_XENLA
Sequence: MAQRYDEMVHYPGLDGMSLAGFADAHTGRALQHHSLSQSTPYGSTGAAHRVPMPPGMGSNDGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDNSGSFPGGDVCSSDSFNEDIAVFAKQVRTEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIDDRDGSSKSDLEDFTGSCTSLSDQNNTWIRDHDETGSTHSGTPGPSSGGLASQSGDNSSEQGDCMDNSVASPSTGDDDDLDRDKKRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTGQGGAPYSPDGQNMGGYVMDGQQHMGIRPPGFQGIPGDYTAAPSTMPMGFPPAGYTPAIPPHSAGLRHGPSLHSYLPGHPHSMILPAGASPHHLVSAQSPADALLNGQNIDIHAH
What is the function of this protein?
A caudalizing protein which is required to pattern the anterior/posterior (A/P) axis during central nervous system (CNS) formation.  Inhibits anterior neural expression and acts as a transcriptional activator to induce posterior neural gene expression.  Maintains a proper A/P balance required for hindbrain formation by activating the FGF/MAPK pathway, which modulates the planar cell polarity (PCP) pathway.  Interacts with retinoid signaling during hindbrain patterning (By similarity).
What are the official names of this protein?
Homeobox protein meis3-B.
What is the protein family that this protein belongs to?
Belongs to the TALE/MEIS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y5038_PSEA7
Sequence: MRLIIVSGRSGSGKSTALNVLEDNGFYCIDNLPASLLPDLAQRALLHTELLHPQVAVSIDARNLPSQLQRFPELLQEVRDNHINCDVLYLDADDETLLKRFSETRRRHPLTTDTRSLAEAIGDESQLLGPIADLADLKLDTTSLNLYQLRDTIKLRLLNKPEPGTAFLVESFGFKRGMPVDADLVFDVRCLPNPYWKPELRDHSGLEPEVREYLAAQPDVEEMYQDIVGYLNKWLPRFAASNRSYVTVAIGCTGGHHRSVYLAERIGAALRESLKNVQIRHRDLNS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein PSPA7_5038.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CNO10_MACFA
Sequence: MAADKPADQGAEKHEGTGQSSGITDQEKELSTNAFQAFTSGNYDACLQHLACLQDINKDDYKIILNTAVAEFFKSNQTTTDNLRQTLNQLKNQVHSAVEEMDGLDDVENSMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQAVCFLLVDLYILTYQAEKALHLLAVLEKMISQGNNNKNGKNETGNNNNKDGSNHKAESGALIEAAKSKIHQYIVRAYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGSTDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFECLIEAVQVYHANPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSIQNTVYNDGQSSAIPVASMEFAAICLRNALLLLPEEQQDPKQENGAKNSNQLGGNTESSESSETCSSKSHDGDKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADKLLQQPKLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSARTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNGNTQLALQIIKRNQLLPAVKTHSEVRKKPVFQPVHPIQPIQMPAFTTVQRK
What is the function of this protein?
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Is not required for association of CNOT7 to the CCR4-NOT complex (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the CNOT10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DPO42_MYCTU
Sequence: MPTAAPRWILHVDLDQFLASVELLRHPELAGLPVIVGGNGDPTEPRKVVTCASYEARAYGVRAGMPLRTAARRCPEATFLPSNPAAYNAASEEVVALLRDLGYPVEVWGWDEAYLAVAPGTPDDPIEVAEEIRKVILSQTGLSCSIGISDNKQRAKIATGLAKPAGIYQLTDANWMAIMGDRTVEALWGVGPKTTKRLAKLGINTVYQLAHTDSGLLMSTFGPRTALWLLLAKGGGDTEVSAQAWVPRSRSHAVTFPRDLTCRSEMESAVTELAQRTLNEVVASSRTVTRVAVTVRTATFYTRTKIRKLQAPSTDPDVITAAARHVLDLFELDRPVRLLGVRLELA
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (By similarity).
What are the official names of this protein?
DNA polymerase IV 2, Pol IV 2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_COCP7
Sequence: MSASPDYKTNLLSHLISNKVLSFGSYTLKSGRNSPYFFTTTLLHTAPLLHATASACASVLSSPPFVTTSTPDGTPRPNFDIIFGPAYKGIPLCTAVLNELGVRDTTGAWNNISYSFNRKEAKAHGEGGNIVGAPLKGKKIVIIDDVITAGTALREAVGIIEKEGGTVVGVLVLLDREERVNDNEKKSAVGCAQRDLGENVPVKAVLSLSDIIEKLGNDIGEENLKRLKEYRAQYGAEE
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TRHO_ECOLI
Sequence: MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDALYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDDGKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYEYEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNKSRGRLNTTLCIPDPTE
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs, the first step in 5-carboxymethoxyuridine (cmo5U) biosynthesis (PubMed:31253794).  May be part of an alternate pathway, which is able to bypass cmo5U biogenesis in a subset of tRNAs under aerobic conditions (PubMed:31253794).
What are the official names of this protein?
tRNA uridine(34) hydroxylase, ORF39.9, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: YOMO_BACSU
Sequence: MASKKLNLSLIEESVNKYDKKEKVQLTDDVHVFIYPYFSPSRLTKMLTEMISDQQKAEDKGIDFSKINTVQWVFFSIVKEFSDLGIPNDIKNKVKWYLKLVDSEFFPMIINSFPKESMKKLKDATKALEKITEDLLTMSHQEINKLILEKVEEIETGSGEVSGENN
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YomO.
Protein: NODE_RHIS3
Sequence: MDRRVVITGIGGLCGLGTDAPSIWKEMREGRSAIGPIVTSELHGLTGTIGAEIKTLPEHDIDRKQLVTMDRFSLLAVLAAREAMRQAGLSCDERNAYRFGAIVGVGGSGWEAIEASYRALLLNGARRAGVMDVPKAMPSAAAGQVSMSLGLRGPVFGVTSACASANHAIASAVDQIRCGRADVMLAGGSDAPFVFCVVKAWEAMRVIAPDTCRPFSSDRRGLVLGEGAGMAVLESYEHATARGATIIAEIAGIGLSADAFNLVSPAVEGPEAAMRACLADAGLNVQDVDYINAHGTGTKANDRMETEAIKRVFGGHANSMSISSTKSMHAHCLGAASALEMIACVMAIQEGVVPPTANYREPDPDCDLDVTPNVARERKVRVALSNAFAMAGMNAVLAFRQV
What is the function of this protein?
Proposed to synthesize NOD factor fatty acyl chain.  Involved in the synthesis of a highly unsaturated fatty acid moiety, which forms part of a lipo-oligosaccharide that is responsible for host specificity.
What are the official names of this protein?
Nodulation protein E, Host-specificity of nodulation protein B.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: DCTN6_CAEBR
Sequence: MTDSSRVSIATSTIVCVEAEIKGEVIIKEGCVVHPHVVFDATNGPIYVGENNIFEEFAVIRNNSEGQPMIIGDSNIFQVHSKCSAKYVGSRNVIGVHAHLEDGCSVSDDCSIGPKCRVFSKQNLEPSVAVYGPSNSHRITSTPNLTPTLQLEFLRKILPSYHHLYNKKKVTAAQ
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Dynactin subunit 6.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: APT_THEVB
Sequence: MDLKSLIRDVPDFPKPGILFRDLTTLLQNQAGLRYVIDQLVEKHANAGIDYVAGIESRGFIFGAPLAYRLGAGFIPLRKPGKLCAPVYAVEYELEYGRDRLEMHQDAIEPGRRVLIVDDLIATGGTAAAAAGLIQKAQAELYGFAFIVELTDLAGRQKLPDVPITTLVTY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG3_PICST
Sequence: MSEPESSVANNDGESTQAPQLAELTLKNVLGDIVNGVHFIIFDPLGNRFVVPVIILLTSIITKVIITKVPYTEIDFVTYMQQIQLVNQGEIDYAEISGDTGPIVYPAGFVQIYQWLYSQTNGGADIATGQSIFGYLMTATVVFVCVAYTMSPTTKPWVLFLLLGSKRLYSIYVLRLFNDCFTTAAMVGVTVFLQQGSYWYSTSSFISFLFAIVGADLFSIAISIKMNALLYLPAVVIIAYFLVGENILLFAIVLAIVPLVQILVGWKFLLPLFDDEAASQIRWNYINNAFNFGRKFLFKWTVNWRFIGEETFLSDKFSILLMGGHIVVLLFFIFTRFLNSKVTGKSIWQLIKDAFKPSSTISSNNKLIDYNVGPKLILLILATTNVIGVLFSRSLHYQFLSWYCWQLPFLLHSTGWNFIVCLVLWGAHEWTWNVYPSTVASSLVLVGILSSVLVGTWRNEAVWFEENNVVDDEKKNE
What is the function of this protein?
Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, Asparagine-linked glycosylation protein 6, Dol-P-Man-dependent alpha(1-3)-mannosyltransferase, Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EFTS_SYNWW
Sequence: MITAEMVKELRERTGAGMMDCKRALVETNGDIEKAIDELRTKGLAKAAKKAGRVASEGVVTSYIHGGGRIGVLVEVNCETDFVAKTNDFKQLAYDIAMQIAASNPEYLNREEVPQEVINREKEILKAQALEEGKPEKVIEKMVEGRVEKFFKERCLLEQAFIKDLDKSVQELINENIARMGENITIRRFARYEVGEGIEKESCDFASEVMSQLK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TARG1_RAT
Sequence: MANPVQPQLQDPGSTSPLDLPEMEKLLTKVENKDDQALNLSKSLSGALDLEQNGHSLPFKVISEGHRQPSLSGSPSRASSRRASSVVTTSYAQDQEAPKDYLVLAIASCFCPVWPLNLIPLIFSIMSRSSVQQGDLDGARRLGRLARLLSITFIILGIVIIIVAVTVNFTVPK
What is the function of this protein?
Regulates insulin-mediated adipose tissue glucose uptake and transport by modulation of SLC2A4 recycling.  Not required for SLC2A4 membrane fusion upon an initial stimulus, but rather is necessary for proper protein recycling during prolonged insulin stimulation.
What are the official names of this protein?
Trafficking regulator of GLUT4 1, Brain endothelial cell-derived protein 1, BEC-1, Dispanin subfamily B member 1, DSPB1, Tumor suppressor candidate 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm, perinuclear region. Note=Shifts from low-density microsome vesicles to the cell membrane upon insulin stimulation.
Protein: GLUCL_CAEEL
Sequence: MATWIVGKLIIASLILGIQAQQARTKSQDIFEDDNDNGTTTLESLARLTSPIHIPIEQPQTSDSKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQPDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANKQGVERKARTEREKAEIPLLQNLHNDVPTKVFNQEEKVRTVPLNRRQMNSFLNLLETKTEWNDISKRVDLISRALFPVLFFVFNILYWSRFGQQNVLF
What is the function of this protein?
Glutamate-gated chloride channel subunit; channel properties depend on the subunit composition.  Glutamate binding triggers a rapidly reversible current in heteromeric channels formed by glc-1 and glc-2, while the anti-helmintic drug ivermectin and other avermectins trigger a permanently open channel configuration.  Channels containing only glc-1 are activated by ivermectin, but not by glutamate alone (in vitro).  The heteromeric channel formed by glc-1 and glc-2 is also activated by ibotenate, and it is blocked by picrotoxin and flufenamic acid (PubMed:7935817).  Plays a role in the regulation of locomotor behavior (PubMed:16527366).
What are the official names of this protein?
Glutamate-gated chloride channel alpha, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, GluCl alpha.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glutamate-gated chloride channel (TC 1.A.9.4) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: AROC_ACIBC
Sequence: MAGNSIGQLFRVTTCGESHGVGLMAIVDGVPPGLALTEEDLQKDLDRRKPGTSKFATQRKEPDQVEIISGVFEGKTTGTPIGLLIRNTDQKSKDYGNIAQTFRPGHADYTYTQKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGVVIRGHVTQIGNEVAEKLDWNEVPNNPFFCGDVDAVPRFEALVTSLREQGTSCGAKLEILAEKVPVGWGEPVFDRLDADIAHAMMSINAVKGVEIGDGFAVAGQFGHETRDELTSHGFLANHAGGILGGISSGQTIRVAIALKPTASITTPGKTINLNREDTDVLTKGRHDPCVGVRATPIAEAMLAIVLMDHFLRHRAQNADVVPPFAPIEP
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: GDF8_LEPCA
Sequence: MQKLQISVYIYLFMLIVAGPVDLNENSEQKENVEKDGLCNACTWGQNSKYSRIEAIKIQILSKLRLGTAPNISEDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQVEGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVKTPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGEGQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: ALDA_STAA3
Sequence: MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGNPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
What are the official names of this protein?
Putative aldehyde dehydrogenase AldA.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: NANP_HUMAN
Sequence: MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSIDCKVSMST
What are the official names of this protein?
N-acylneuraminate-9-phosphatase, Haloacid dehalogenase-like hydrolase domain-containing protein 4, Neu5Ac-9-Pase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. NANP family.
Protein: TOG1B_AGEAP
Sequence: ERGLPEGAECDGNESDCKCAGAWIKCRCPPMWHING
What is the function of this protein?
Omega-agatoxin are antagonist of voltage-gated calcium channels.  They block insect neuromuscular transmission presynaptically.  This toxin is a blocker of L-type calcium channels (Cav/CACNA1).
What are the official names of this protein?
Omega-agatoxin-Aa1b, Omega-AGTX-Aa1b, Omega-agatoxin IB, Omega-Aga-IB, Omega-agatoxin-1B.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 04 (omega-agtx) family. 01 (type I omega-agtx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPF_PSYWF
Sequence: MLIEFTKMHGLGNDFMVIDLVTQRLELTPELITLLADRNLGIGFDQLLVVEPPMRPDVDFRYRIFNSDGSEVEQCGNGARCFARFVQARKLSFKQRIRVETKSGILTLSTDNYGWVEVDMGKPRFEPAEIPFTPKAITKIQNAYHLDVEGTPVQLYVANMGNPHAVIKVDDILTADVEKLGKAIESHPAFPERVNVGFMQVMNQRHIRLRVYERGVGETQACGTGACAAVATGIREGWLDEGEEIRAQLYGGSLLIRWSPGYSVMMTGPTAFVYEGVFSPDGIMAQAGLKPLS
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_SOLM1
Sequence: MLHVSTIEGQLDAKGLKFALVAGRFNDFITERLVGGAVDYLVRHGGDRADLTIVRVPGAFEIPLAAKKLAASGKYHGIICLGAVIRGSTPHFDFVASECAKGLAHVMLDANVPVGFGVLTVDNLEQAIERAGSKAGNKGVEAASAVLEMVRVLEQI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.