PharMolix/UniProtQA huggingface dataset:
Protein: LMBL4_MOUSE
Sequence: MRQPNRKRKLSLESTERMNQDRCTGQTEEEKKPGEVTTPSKRESSVTTAETWSWEQYLREGNAVAAPVELFSKDQSFPEHENGFQVGMRLEGIDARRPSVFCVLSVAEVCGYRLRLHFDGYLSCYDFWTNAGSPDIHPVGWCQKTKHELHIPRDYRKDKFVWMDYLKACRLQNAPKKLFRNRSSNGPVPREFQVGMKLEAVDRRNPCLMCVATIADIVEDRVRVHFDSLDDSFDYWCDVNSPYIQPVGWCQENGRTLVAPQGYPHPDKFSWTDYLRASQSKAVPAKAFGMRTPHGFLPNMKLEAVDKRNPQLIRVATIADVDDYRVKIHFDGWDHKYDYWVDADSQDIHPIGWCDVTGHPLEVPYGSKHVKILPGQPACPTPGCRGIGHIRGPRYAGHHSAFGCPYSDVNLKREAALQDRLREQTQANLELDPSHSKSENPCNLNVNGKCENANSQCRLVQQAKCLKIKGKEDIDLDNLFRVLVFHPRRLEYSAAQVQQMLHQPLSMTSTSAHPFRDIPLSREQHCKLLPGVADIQASQVARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQADIVKVMRIKLGPALKIYNSILMFRNSQDVTEDASSQEDKR
What is the function of this protein?
Putative Polycomb group (PcG) protein.  PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity).
What are the official names of this protein?
Lethal(3)malignant brain tumor-like protein 4, L(3)mbt-like protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALL6_APICE
Sequence: MPRLVLVSFLFLAIFSVFIGGFAKSKCPRNEIFTRCHAACQPSCARLARKPFCIKICKPGCICTSGYLRNKNNVCVPRSRCFSGRLL
What is the function of this protein?
Antifibrinolytic and antimicrobial serine protease inhibitor.  Inhibits trypsin, plasmin and microbial serine proteases but not chymotrypsin, thrombin and elastase.  Inhibits the plasmin-mediated degradation of fibrin to fibrin degradation products.  Also binds to bacterial and fungal surfaces and exhibits antimicrobial activity against fungi as well as Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Venom serine protease inhibitor, AcVSPI, VSPI, Allergen Api m 6-like peptide.
What is the protein family that this protein belongs to?
Belongs to the serine protease inhibitor-like (TIL domain-containing) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TFF1_HUMAN
Sequence: MATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTIDVPPEEECEF
What is the function of this protein?
Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents.  May inhibit the growth of calcium oxalate crystals in urine.
What are the official names of this protein?
Trefoil factor 1, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1.A, hP1.A, Protein pS2.
What are the subcellular locations of this protein?
Secreted.
Protein: PI4KB_RAT
Sequence: MGDMVVEPATLKPTSEPTPSPSGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVKLLHGGVAISSKGSPLELVNGDGVDNEIRCLDDPPTEIREEEDEMEPGVVSGTAKGTRRRRQNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKPAHRKRELPTLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTNVPARIPENRIRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNISQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
What is the function of this protein?
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP) (PubMed:8973579).  May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation (By similarity).  Involved in Golgi-to-plasma membrane trafficking (PubMed:8973579).
What are the official names of this protein?
Phosphatidylinositol 4-kinase beta, PI4K-beta, PI4Kbeta, PtdIns 4-kinase beta.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
What are the subcellular locations of this protein?
Golgi apparatus. Endomembrane system. Mitochondrion outer membrane; Peripheral membrane protein. Rough endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane. Note=Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5- bisphosphate (PIP2) on the Golgi complex. Recruited to the Golgi apparatus membrane by ACBD3, GGA2 is also involved in the recruitment.
Protein: CXG1_DANRE
Sequence: MSWSFLTRLLDEISNHSTFVGKIWLTLFIIFRIVLTVVGGESIYYDEQSKFVCNTQQPGCENVCYDAFAPLSHVRFWVFQIILITTPTIMYLGFAMHKIARSNDVEYRPVNRKRMPMINRGRNRDYEEAEDNGEEDPMIMEEIVPEKEKAPEKSAVKHDGRRRIKRDGLMKVYILQLLSRIIFEVGFLFGQYILYGFEVAPSYVCTRSPCPHTVDCFVSRPTEKTIFLLIMYAVSCLCLSLTVLEILHLGLSGIRDAFRRRARHQSVQRPRAPICRQVPTAPPGYHTALKKDKLSLGMKPEYNLDSGRESFGDESSSRDIDRLRRHLKLAQQHLDLAYQNGESSPSRSSSPESNGTAVEQNRLNFAQEKQGSKCEKGIHA
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.  Participates in a developmental pathway for formation of the notochord and tail.
What are the official names of this protein?
Gap junction gamma-1 protein, Connexin-43.4, Cx43.4, Gap junction alpha-7 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Gamma-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: PO4F3_HUMAN
Sequence: MMAMNSKQPFGMHPVLQEPKFSSLHSGSEAMRRVCLPAPQLQGNIFGSFDESLLARAEALAAVDIVSHGKNHPFKPDATYHTMSSVPCTSTSSTVPISHPAALTSHPHHAVHQGLEGDLLEHISPTLSVSGLGAPEHSVMPAQIHPHHLGAMGHLHQAMGMSHPHTVAPHSAMPACLSDVESDPRELEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKYSAVH
What is the function of this protein?
Acts as a transcriptional activator (PubMed:18228599).  Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes (PubMed:18228599).  Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear (By similarity).
What are the official names of this protein?
POU domain, class 4, transcription factor 3, Brain-specific homeobox/POU domain protein 3C, Brain-3C, Brn-3C.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Preferentially localized in the nucleus.
Protein: Y1402_BACHK
Sequence: MNTPVSVNEKKDFVKWFLNNYQLKQRECVWILNYLMSHDQLMHKVHFVEHAKYCPRGLVMSANCVKDTPFHFFKQNVMTTDAEKSFHDIRLNRDEDIYIQLNFKSSFQNANYVAVLEENPYLPKHIEVNEKDRLLAERFLEESVFSFRRERLLKQIDEALDKQDKEAFHRLTAELKML
What are the official names of this protein?
UPF0302 protein BT9727_1402.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: LIPA_PYRTR
Sequence: MATSIPRSRCFLTSSTLKVVPRSRTPLRSFATTSDTPQTSVPEAPGKRSRPPTSFSDTLNAGPSFGDFVNPNAPLSPTEAYEIKTVQVGPEGRKKTITRLPEWLRTPIPSNANQNYKQIKKDLRGLNLATVCEEARCPNISDCWGGSSKSAATATIMLMGDTCTRGCRFCAVKTSKAPPPLDPHEPENTAEALRRWGLGYVVITVVDRDDLADSGAHHIAETIMKIKQKNPTQLVELLGGDYGGNLEMAKVVARSGVDVFAHNIETTERLTPFVRDRRAKFRQSLDVLRSAKEERPELITKTSMMLGLGETDEDLWHALRELRANNVDVVTFGQYMRPTKRHMAVHDYVTPDKFELWRQRALDMGFLYCASGPLVRSSYKAGEAFIENVLKKRRLGSSAGKNDVAELSAAEEVGKAL
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ASTC_SHIBS
Sequence: MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIMAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPPDIRHAAYNDINSASALIDDATCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGDFPVGALLTTEECASVMTVGTHGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTINHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAAACEHFVSRGSS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, SOAT, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: RL32_BACMK
Sequence: MAVPFRRTSKTVKRKRRTHFKLSVPGMVECPSCGEAKLAHRVCKACGTYKGKEVISK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: PA2H2_BOTPI
Sequence: SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKADDC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) homolog that lacks enzymatic activity (PubMed:10863008).  Shows myotoxic activity and edema-inducing activities in vivo (PubMed:10863008).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog piratoxin-2, svPLA2 homolog, Piratoxin-II, PrTX-II.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_XYLFA
Sequence: MSIDTQSIIENNKRSAHDTGSPEVQVALLTARIELLTKHFKIHKKDHHSRRGLLQMVNRRRSLLDYLNKKDNERYKLLIEKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GSA2_STAA8
Sequence: MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHNNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIKQTLKAADYAFSQMK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MF13A_MOUSE
Sequence: MGLDWPQAWLLGLPIAVVYGSLALFTSILHNVFLLYYVDTFVSVYKINKVSFWVGETVFLLWNSFNDPLFGWLSDRQLLSSQPRSGAGLSSRDVVLTRVRALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSSHDRTHLNFYCSLFSAAGSLSVFASYAFWNKEDFSSFRAFCVVLAAGSGLGFLGTTQLLKRQIEATRRDRGCPGLDLDGGVCEEEPPVGGEEAGNITLGQYLRQLARHQNFLWFVGMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSFLLGISYVAPHLNNLYFLPLCRRWGVYAVVRGLFLLKLSLSLLMLLAGPDHPGLLCFFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTGHDLFQQSPMTPVGSVRPWPELPAPAPAPAQAPTLRQGCFYLLVFVPITCALLQLFTWSQFTLHGRRLRTVKAQRQNLAQIHTLNIKMV
What are the official names of this protein?
Transmembrane protein 180, Major facilitator superfamily domain-containing 13A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1264_BACAA
Sequence: MLYLHDVWVNWFEGEENGYNVCHFYEWRKDDTIELLDQVPLLKVDSTLYHYIENELLELPQKLLEDVHHKAYIRKNHERLQQEYCFVVTDGKGIIAIDTIGYNVPIRKSRLIPRQEQMVYEMVENVQAEKYEFQVEEMEKEHHILSPSPFVMNGLTRKERQLKQLLFMALDQLHTTKNTAEIRYWFTEWDPSAYGMVQHMEFEDIWAKLYDEAKTGWSEKHEQLCERLVKGQPFFEKLWEMENEQKVN
What are the official names of this protein?
UPF0736 protein BAA_1264.
What is the protein family that this protein belongs to?
Belongs to the UPF0736 family.
Protein: RPOZ_CAMC5
Sequence: MRTEQITAKALKQIGDDRYKLSLIVAKRAEALANGAQALIEGDTSKMKFADIALMEVAEGKIGLEAIVEGK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: HTPX_PSEE4
Sequence: MMRILLFVATNLAVVLVASITLSLFGFNGFMAANGVDLNLGQLLVFCAVFGFAGSLVSLFISKWMAKMTTGTQIITQPRTRHEQWLLQTVEELSREAGIKMPEVGIFPAYEANAFATGWNRNDALVAVSQGLLERFSPDEVRAVLAHEIGHVANGDMVTMALVQGVVNTFVMFFARIIGNFVDRVIFKNEEGHGIAYFVATIVAELVLGILASIIVMWYSRRREFRADEAGAHLAGTGAMIGALQRLRSEQGLPVHMPDTMKAFGINGGLKHGLAGLLMSHPPLEDRIDALRRRG
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTS_ACIB3
Sequence: MNSAEIMADLSNHTPMMQQYLKVKKDYQHALLFYRMGDFYELFFEDAHLAAKLLGITLTHRGKANGNPIPMAGVPYHSAEGYLARLVKAGRTVAICEQVGEVTGKGPVERKVVRILTPGTLTDDALLTSYQSSNLVALCIHQNQIGFALLDLSAGIFKVQQQDYKPEQLPIELARLMPSEILIDEDLVDPNIIEQIKKHLDCPVTKRPNVDFNLNNAQKTLCDQFSVSTLSGFGLDPLPLAKAAAAALIHYAKETQKTALPHIRSILLEQSSDFIALDPITRRNLEIIEPLFEHGTSLFQLVNDCQTAMGGRLLSRTLMQPVRDTALLDARLDAIEQLIQGYHESPVRLVLKEIGDIERVLSRVALGSARPRDLVQLRHACAQIPFLRNALAPVVQAKKSKLLGQLDQELGDFKSLHQHLMAAIVENPPVLLRDGNVIAEGYDAELDELRQIRDHAGQFLIDLEIKERERTGISTLKIGYNRVSGYYIELTRAQAEQAPADYIRRQTLKNAERYITPELKSFEDKVLSSESRALAREKALFEALLENLRENIAHLQMMSSAIAQIDVIANFAHQARLNNWARPEFTPETGIKIQGGRHPVVEALSKAPFTPNDTFLDVQHRMAIITGPNMGGKSTFMRQTALISLLAYCGSYVPARAAKLGPIDRIFTRIGSADDLSTGKSTFMVEMTETSQILHHATNQSLVLMDEVGRGTSTYDGLSLAWACVVDLTKRVKCLCLFATHYFELTELGSEPGIDNYHVTAQELNGNLILLHKVQQGPASQSHGLQVAKLAGIPANVIKEAQKRLRILEKQQQQHLQTSVQSDLFATLDSEVTPSTQVIEKVIEVEVSSPALDLLKQIEVDNLTPRQALEQLYELKAALNS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: STP1_YEAS7
Sequence: MPSTTLLFPQKHIRAIPGKIYAFFRELVSGVIISKPDLSHHYSCENATKEEGKDAADEEKTTTSLFPESNNIDRSLNGGCSVIPCSMDVSDLNTPISITLSPENRIKSEVNAKSLLGSRPEQDTGAPIKMSTGVTSSPLSPSGSTPEHSTKVLNNGEEEFICHYCDATFRIRGYLTRHIKKHAIEKAYHCPFFNSATPPDLRCHNSGGFSRRDTYKTHLKARHVLYPKGVKPQDRNKSSGHCAQCGEYFSTIENFVENHIESGDCKALPQGYTKKNEKRSGKLRKIKTSNGHSRFISTSQSVVEPKVLFNKDAVEAMTIVANNSSGNDIISKYGNNKLMLNSENFKVDIPKRKRKYIKKKQQQVSGSTVTTPEVATQNNQEVAPDEISSATIFSPFDTHLLEPVPSSSSESSAEVMFHGKQMKNFLIDINSFTNQQQQAQDNPSFLPLDIEQSSYDLSEDAMSYPIISTQSNRDCTQYDNTKISQILQSQLNPEYLSENHMRETQQYLNFYNDNFGSQF
What is the function of this protein?
Transcription factor involved in the regulation of gene expression in response to extracellular amino acid levels.  Synthesized as latent cytoplasmic precursor, which, upon a signal initiated by the plasma membrane SPS (SSY1-PTR3-SSY5) amino acid sensor system, becomes proteolytically activated and relocates to the nucleus, where it induces the expression of SPS-sensor-regulated genes, including the amino-acid permeases AGP1, BAP2, BAP3 and GNP1.  Binding to promoters is facilitated by DAL81.  Involved in the repression of genes subject to nitrogen catabolite repression and genes involved in stress response.  Negatively regulated by inner nuclear membrane proteins ASI1, ASI2 and ASI3, which prevent unprocessed precursor forms that escape cytoplasmic anchoring from inducing SPS-sensor-regulated genes.  May be involved in pre-tRNA splicing (By similarity).
What are the official names of this protein?
Transcription factor STP1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Note=Localizes to the cytoplasm in its unprocessed form and is targeted to the nucleus after proteolytic processing upon induction by amino acids. The SCF(MET30) ubiquitin ligase complex negatively regulates nuclear accumulation of the processed form in the absence of high extracellular methionine levels (By similarity).
Protein: RSMF_SALDC
Sequence: MAQHAVYFPDAFLTQMREAMPSTLSFDEFISACQRPLRRSIRINTLKISVADFLALIAPYGWSLTPIPWCHEGFWIERDDEEALPLGSTAEHLSGLFYIQEASSMLPVAALFADDNHPQRVMDMAAAPGSKTTQIAARMGNRGAILANEFSASRVKVLHANISRCGIANTALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNLDIAATQRELLNSAFHALRPGGTLVYSTCTLNRQENEEVCLWLKETYADAVEFLPLGDLFPDADRALTPEGFLHVFPQIYDCEGFFVARLRKMSSLPAMPAPGYKVGAFPFTPLKGREALHVTQAANAVGLLWDENLHLWQREKEVWLFPAEIESLIGKVRFSRLGIKLAESHNKGYRWQHEATIALACPTHAHAFELSVQEAEEWYRGRDIYPQTPPAADDVLVTFQHQPLGLAKRIGARIKNSYPRELVRDGKLFTGNS
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_NITHX
Sequence: MAPITGSNFHLHLVSDSTGETLITVSRAVVAQYANVTPVEHVYPLVRSQKQLDRVLAEIEEEPGIVLFTLLEKDLVERLEAKCQEINSPSLSIIGPVMQLFQAYLGAATIGRVGAQHTLNADYFRRIDALNYTMMHDDGQHVEGLEEADVVLVGVSRTSKTPTSIYLANRGIRTANVPLVPGIAIPRQLESLRTPLVVSLHAAPERLIQVRQNRLLSIGTRAGNDTYIDRQSVADEVTYARRLSAKHDWVQLDVTRRSIEETAAAIMKLFADRQRQRQPE
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: PRMA_SYNWW
Sequence: MKWKEIAVLTEGICIEAIAGIFHRLGSGGVVIEDPQAARKYENQEEWNPNLVSPDFLDHEFVLIKAYFMEEREVMEELQSCLETVKENFNVECKVFIDEVRDEDWESSWKKYYHRFKIGERLVIKPSWEEYQPQSGEVVIDIDPGMAFGTGIHASTRFCMKFIDHYVKGGEKLIDAGCGSGILSIAAAKLGAARVLAMDVEELSVKIARENVELNGLSDIITVKLGNIVEEIQTFEADMVAANITAEVVTCLIPEAAKVLKSGGYFFGSGIVDSRWPGVEKQLKTHGFVIEQVLQDVDWIGVAARKE
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABRA_ABRPR
Sequence: QDRPIKFSTEGATSQSYKQFIEALRERLRGGLIHDIPVLPDPTTLQERNRYITVELSNSDTESIEVGIDVTNAYVVAYRAGTQSYFLRDAPSSASDYLFTGTDQHSLPFYGTYGDLERWAHQSRQQIPLGLQALTHGISFFRSGGNDNEEKARTLIVIIQMVAEAARFRYISNRVRVSIQTGTAFQPDAAMISLENNWDNLSRGVQESVQDTFPNQVTLTNIRNEPVIVDSLSHPTVAVLALMLFVCNPPNANQSPLLIRSIVEKSKICSSRYEPTVRIGGRDGMCVDVYDNGYHNGNRIIMWKCKDRLEENQLWTLKSDKTIRSNGKCLTTYGYAPGSYVMIYDCTSAVAEATYWEIWDNGTIINPKSALVLSAESSSMGGTLTVQTNEYLMRQGWRTGNNTSPFVTSISGYSDLCMQAQGSNVWMADCDSNKKEQQWALYTDGSIRSVQNTNNCLTSKDHKQGSTILLMGCSNGWASQRWVFKNDGSIYSLYDDMVMDVKGSDPSLKQIILWPYTGKPNQIWLTLF
What is the function of this protein?
The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis.
What are the official names of this protein?
Abrin-a.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the ribosome-inactivating protein family. Type 2 RIP subfamily.
Protein: Y894_HAEIN
Sequence: MKIILVVFVLIFVGVIGFNMIKGVMISRAIAGMPESSSPVTALEVQPREWTPVINTTGLVRPNQGAMLSTQNAGAVSQVLVQNGQNVKKGEVLVELDSSVERANLQAAQAQLSALRQTYQRYVGLLNSNAVSRQEMDNAKAAYDAQVASIESLKAAIERRKIVAPFDGKAGIVKINVGQYVNVGTEIVRVEDTSSMKVDFALSQNDLDKLHIGQRVTATTDARLGETFSARITAIEPAINSSTGLVDVQATFDPEDGHKLLSGMFSRLRIALPTETNQVVVPQVAISYNMYGEIAYLLEPLSEEEKGKMSGNEKLDRLYRAKQITVFTKDRQGVYAQLQGNEVKVGDKIITGGQQGIGNGSLVEWIKKDIVGAIEPAHKTPL
What are the official names of this protein?
Uncharacterized protein HI_0894.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GATB_ANADF
Sequence: MPVSDFQVVLGLEVHAQLLTRSKIFCACPTEFGGAPNTHVCPVCLGLPGALPALNAAVVEMAIRTGLALGCEIQRRSVFARKNYFYPDLPKGYQISQYELPICSGGGVDIAVGGEARRIRLTRIHMEEDAGKNVHDVTAAGSGVDLNRAGVPLLEIVSEPDLRSIDEAIAYLKSLRAILMALGVNDGNLQEGSFRCDANVSVMPRGATRLGTRCELKNMNSFRFLRQAIDYEVRRQVELIESGGKVDQETRLFDPDRGETRSMRSKEEAHDYRYFPEPDLPPVLVDEALVERIRRELPELPRARSARYQRDLGLSAQDAELLVSDKGIGDFFDATLAAYGASPDAAKRIANLLNGDVARLANELSLEPAAWRIAPAQLAAILRLQDAQTIGGPGAKQVVEEVFRSGAEPAEVVREKGLAQVSDEGALEAAVDRVLAASAGEVERYRGGNKKLLGFFVGQVMKETRGKGNPAVVNALLKRKLGG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: Y4SO_SINFN
Sequence: MENKSLQPPLPRSERRIRVLHNDVTIDSYGWLRDREDPDVLAYLEAENHYADEVTSYVAELKADLIAEIEKRDSCDGAPPPFQVGFFFYFQKSQSGLLHSAWWRRPVTGGPEELVFDPNTLPGAEVFYSLGALEPSDDGRYIAFSFDLIGNERYELRVRDMTNGREIWRDPSRAGRLVWAADNRTLFFTRERADRRQHDRVVRLDVETGRSEVVFEEVNERLALVVRRSGSGAYLFIDVIITSDMSSRIQRAAAEVWCLPAERPTDMWRRILARELGHEIYAEHWGNEFLFRVNDTGPNLRLVRTAIDDTSPSRWQEVVPHRAGITLEEIHVLEEHVIVLEREGIQPRLVAHHRNGRVGPSIVPVEHSCTVTVGLSAGGSYSCARHPYRVSALTYKICSFVTPDIFIQHDLLTDKSKVLYRTLVSGFEPELYEARVVMAKAEDGVEVPISIVARRDRGEDGPVLLNVYGCYGAQSLPAFFGWPSSMTARLSLLDRGVAFGIVHVRGGGELGRAWHEAATRDQKRLTHTDLIAAAECLVEHRFASRDGIVIEGRSAGGGTVLAAAVLRPDLFRAVLAEVPLADIIDTELDFTLPYALRETAEYGDPHLANDYQYLRSYDPYYNLTPDRRYPPTYIDAALHDSQVLYYQPARYVAQRRSKAVDRDPDLIFRTRMIGGHMGVSHGPGVAEEAAFRMAWILHRLGQSGR
What are the official names of this protein?
Uncharacterized peptidase y4sO.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.