PharMolix/UniProtQA huggingface dataset:
Protein: PELO_IGNH4
Sequence: MRVLEVNESKGEVKVRVEDEEDVWILHSALRPGDLVRARTARSVAGSSGKEKIPMTLTIKVTGSEFQAFSNVLRVKGVVVEGPDKFGLIGSHHAIKVYPGKEITIIRERGLAQLLERLKKGEERKPQVPVLAVDYDEYSLAVVRGQGIEWVFEGSLRLPGKGDEGREAATERKINELAKRVSEELKLRNLDHVVVVGPGFLKDKVAQRLSEEGFKVKVDSASSGGRAGVLEAIRKGSLRGVAKELESIKALEALEEFVKHVARGDGYALYGVDDCMTAAQANAVKTLIISDDLLHSPDLGERAVELVELAEKKGAEVIIVPKGTEAWERLRPFGDVVCLLRFPISL
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDEC_SYNY3
Sequence: MPELAVRTEFDYSSEIYKDAYSRINAIVIEGEQEAYSNYLQMAELLPEDKEELTRLAKMENRHKKGFQACGNNLQVNPDMPYAQEFFAGLHGNFQHAFSEGKVVTCLLIQALIIEAFAIAAYNIYIPVADDFARKITEGVVKDEYTHLNYGEEWLKANFATAKEELEQANKENLPLVWKMLNQVQGDAKVLGMEKEALVEDFMISYGEALSNIGFSTREIMRMSSYGLAGV
What is the function of this protein?
Catalyzes the decarbonylation of fatty aldehydes to alkanes.  Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity).  Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane.
What are the official names of this protein?
Aldehyde decarbonylase, AD, Fatty aldehyde decarbonylase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde decarbonylase family.
Protein: AB17C_HUMAN
Sequence: MPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQRGAGASAPAPAQATAAAAAAQPAPQQPEEGAGAGPGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHGNAVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPSIDKISKVTSPVLVIHGTEDEVIDFSHGLAMYERCPRAVEPLWVEGAGHNDIELYAQYLERLKQFISHELPNS
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins.  Has depalmitoylating activity towards NRAS and DLG4/PSD95.
What are the official names of this protein?
Alpha/beta hydrolase domain-containing protein 17C, Abhydrolase domain-containing protein 17C.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD17 family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendritic spine. Postsynaptic density membrane.
Protein: YLS5_CAEEL
Sequence: MEHLLLFLSCLSMLVSIAFQSVLLPLILHLFSFFLLSFLSFLHFRSFSANNFKHHSLFLVPKRRSFSISVLPAAAPSSPSSNSFLFPSLSHYFYSLRDTTMVKLTESAVYIRTKCSLENVKKLNLWGCGIDDIQVCEKMSLLEVLSLSVNEVKSLAPLQHCKNLKEVYLRKNCLESLDELEYLKELPNLRTLWIDENPCVGEGGQEYRRKVIRVLPNLTKLDDKPVTTTDHQEAIEDSIPECDMHNSHYSARSNRSNSIDLMSRSLYVGPTVVDRIVQPQLLHFGDTSDEERTTYPARSFSVEVPGLPLTEDHTTVYLDSAPQSHIGSRHNLMSQSMYGTLCGTLAEEPSSADGEDDWNDFSIEEDRVMVQMPLAASHRMYQSMHEGMVIEMKRPPVYGRSVSMPRRRATNLTTRASSMSPAREQRLTKIMSAVSVLLDELDTDGLRQVVDEAQRRLKKQR
What are the official names of this protein?
Uncharacterized protein F09G8.5.
Protein: SOML_ACITR
Sequence: MQKVKVLQVCAWVLLLWRCWGVLGYPLDCKDEQGSIISCTSISLEKLLDRVIQHAELIYHVSEESCTLFEEMFVPVSMRTQQNRARNTCITKAFPIPGSKSEIQKISDKWLLHSVLMLVQSWIEPLVYLQKTLDRYDDAPDTILNKTKWVTNKLSSLEQGIVELIRKMLDEGLLAVDHQQTLTRFDVQPEVVESILRDYAVLTCFKKDAHKMEVFLKLLKCRHTDKMSCYIS
What are the official names of this protein?
Somatolactin, SL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPP_LACDA
Sequence: MLDIFKAIILGIIEGVTEFLPISSTGHLYLADYIIKLDQPTSFINMFMVVIQLGAILSVIVIYFNKLNPFAPSKSKREKGQTWQIWFKVIAAVLPSIIIGLPLNDWLEENMTSWQVISATLIIYGILFIVLENYYAKRQPSLTDLNKMSNKTALLIGCFQVLSMIPGTSRSGATILGAMLIGSSRYVATEFSFFLAIPTMFGASLLKLVKFFKAGHVFVGNQLAILLVGMVVSFIVAYLSIKFLLKYVQTHDFKPFGWYRIVLGIIVTICGLVFA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOB_BARVE
Sequence: MLGDGKEGTSTIPGFNQIQFEGFYRFIDQGLIEELSKFPKIEDIDHEIEFQLFMETYQLVEPLIKERDAVYESLTYSSELYVSAGLIWKTSRNMQEQRIFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYQSELDHNGISVYTGTIISDWGGRLELEIDKKARIWARVSRKQKISILVLSSAMGSNLREILENVCYPEIFLSFLTDKEKKKIGSKENAILEFYQQFSCVGGDPIFSESLCKELQKKFFHQRCELGRIGRRNINWRLNLNIPQNNIFLLPRDILAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQLGLALARLENVVKGTISGAIRHKLIPTPQNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTANFRIRDIHPSHYGRICPIDTSEGINVGLIGSLSIHARIGDWGSLESPFYELFEKSKKARIRMLFLSPSQDEYYMIAAGNSLALNRGIQEEQAVPARYRQEFLTIAWEEVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQVALDSGVPAIAEHEGKILYTDTEKIVFSGNGDTLSIPLIMYERSNKNTCMHQKPQVRRGKCIKKGQILADGAATVGGELALGKNILVAYMPWEGYNFEDAVLISECLVYGDIYTSFHIRKYEIQTHVTTQGPERITKEIPHLEGRLLRNLDKNGIVMLGSWVETGDILVGKLTPQVAKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWVQKKGGSSYNPEIIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFECSLGLAGSLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRSKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPKPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKEV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DCR1B_DANRE
Sequence: MNGKVLPDTPIAVDCWQLRKCLHVRLFFLSHMHSDHTCGLSSTWSHRPIYCSPLTAKLLRLKLQIKQKWIRPLEIGQDHMLMLDDLGKERLTVNLIDANHCPGAVMFLFQGYFGTRLYTGDFRYTPSMLRVPCLQNHINIDVLYLDNTNCDPTRALPSRQQATQQIKQIIRDHPGYAVVIGLYSLGKESLLVDLAMEFKTWVEVDRERLETLRVLQLPDVFTTDSGAGRIRVVNQSMISASNLMAWNKLQSTIAILPTSRPMVSCHPNVYVVPYSDHSSYQELEDFVSALSPISLVPIVGNCLPYFSSLLSPRKKPKAVVIPESVKQYMMTNSNIRSSTNGMIQRTSRPEVRGVVFDSPETKLSQPNHDDMDSNDTEIDHDTTDRNSDSDCILLDMGTNSYHRDNDQGNKRLKLIRIESEDVVTVTSSLTMDDNESVSTRKGIGSPDPSLIYECDHESPTKSSKEKSPEMGSTNSGEMCSSMDSMHDQTSLTTAAALTLPNPQSVTSAIPITLESEQFEHWLLENFTIPAEELKEGQVLRGLCENYRLNPVDLPKPVGDPLEAAIKRLMSN
What is the function of this protein?
5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase.  Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse.  Plays a key role in telomeric loop (T loop) formation by being recruited by terf2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways (By similarity).  Possesses beta-lactamase activity, catalyzing the hydrolysis of penicillin G and nitrocefin (By similarity).  Exhibits no activity towards other beta-lactam antibiotic classes including cephalosporins (cefotaxime) and carbapenems (imipenem) (By similarity).
What are the official names of this protein?
5' exonuclease Apollo, Beta-lactamase MBLAC2, DNA cross-link repair 1B protein, SNM1 homolog B.
What is the protein family that this protein belongs to?
Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
What are the subcellular locations of this protein?
Chromosome, telomere. Nucleus.
Protein: ALGE4_AZOVI
Sequence: MDYNVKDFGALGDGVSDDRASIQAAIDAAYAAGGGTVYLPAGEYRVSAAGEPGDGCLMLKDGVYLAGAGMGETVIKLIDGSDQKITGMVRSAYGEETSNFGMRDLTLDGNRDNTSGKVDGWFNGYIPGGDGADRDVTIERVEVREMSGYGFDPHEQTINLTIRDSVAHDNGLDGFVADYLVDSVFENNVAYANDRHGFNVVTSTHDFVMTNNVAYGNGSSGLVVQRGLEDLALPSNILIDGGAYYDNAREGVLLKMTSDITLQNADIHGNGSSGVRVYGAQDVQILDNQIHDNAQAAAVPEVLLQSFDDTAGASGTYYTTLNTRIEGNTISGSANSTYGIQERNDGTDYSSLIDNDIAGVQQPIQLYGPHSTVSGEPGATPQQPSTGSDGEPLVGGDTDDQLQGGSGADRLDGGAGDDILDGGAGRDRLSGGAGADTFVFSAREDSYRTDTAVFNDLILDFEASEDRIDLSALGFSGLGDGYGGTLLLKTNAEGTRTYLKSFEADAEGRRFEVALDGDHTGDLSAANVVFAATGTTTELEVLGDSGTQAGAIV
What is the function of this protein?
Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), but introduces almost exclusively MG blocks, producing a polymer with non-gel-forming capacity.
What are the official names of this protein?
Mannuronan C5-epimerase AlgE4, Poly(beta-D-mannuronate) C5 epimerase 4.
What is the protein family that this protein belongs to?
Belongs to the D-mannuronate C5-epimerase family.
What are the subcellular locations of this protein?
Secreted. Note=Probably exported via the hemolysin-type secretion pathway.
Protein: VE7_HPV51
Sequence: MRGNVPQLKDVVLHLTPQTEIDLQCYEQFDSSEEEDEVDNMRDQLPERRAGQATCYRIEAPCCRCSSVVQLAVESSGDTLRVVQQMLMGELSLVCPCCANN
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: Y2039_PROMH
Sequence: MDYEFQRDLTGGILARFSMDHEAIGYWLNDEIQGDISLIDQILTEMDEVKGSEKQWQLIGKEYSLSIDDEEIMVRANTLHFETDDLEEGMSYYDNESIAFCGLDDFATMLQKYRLFILENRRS
What are the official names of this protein?
UPF0231 protein PMI2039.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: Y7068_DICDI
Sequence: MSRRMGGGMPKINLSGAIPNNNTSTPSTPTLRSSVSVSSSNSRGLFLA
What are the official names of this protein?
Putative uncharacterized protein DDB_G0276433.
Protein: TFXG_RHILT
Sequence: MNDEICLTGGGRTTVTRRGGVVYREGGPWSSTVISLLRHLEASGFAEAPSVVGTGFDERGRETLSFIEGEFVHPGPWSEEAFPQFGMMLRRLHDATASFKPPENSMWRDWFGRNLGEGQHVIGHCDTGPWNIVCRSGLPVGLIDWEVAGPVRADIELAQACWLNAQLYDDDIAERVGLGSVTMRAHQVRLLLDGYGLSRKQRGGFVDKLITFAVHDAAEQAKEAAVTPESNDAEPLWAIAWRTRSASWMLHHRQTLEAALA
What is the function of this protein?
Required for TFX resistance.
What are the official names of this protein?
Trifolitoxin immunity protein.
Protein: G6PI_BRUSI
Sequence: MARDATKLEATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINNTEDRVVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHDGPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAAVSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRKA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_CLOPS
Sequence: MYEYIRGQFQGISKDYVVIELNNIGYRIFTSGNTMSNMPKVGDEVLLYLEQIVREDFIGLYGFTTKEELEMFKLLLSINGVGAKAALSLLSISTVNNLKYAIMMGDEKHITRAPGIGKKTAQRIILELKDKLKPDELTSEEEQLIEGINDNSDYSFNINETLSALMALGYTEKEAQKALEKVDKTLSIENMIKESLKLLMR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SNH12_HUMAN
Sequence: MQGTWLPPSFLAVCDTEEVSLFLELCFKIHVTCKAVLICDYGPMELGQSLWEAEGKDPGHFR
What are the official names of this protein?
Putative uncharacterized protein SNHG12, Transformation-related gene 11 protein, TRG-11.
Protein: RSMH_RHIWR
Sequence: MTTTAPHVPVLIDEVIAGLEPATGETHVDGTFGAGGYTRALLQAGARVYAFDRDPDAIAEGRALEDGQDGRLILVPERFSRMAEALNERGIDQVDGVTLDIGVSSMQLDRADRGFSFQADGPLDMRMEKSGMSAADFVNTADEAEIADVLHDLGEEPRARRVARAIVQARPITRTSELAEVVRRALGHKPHEKKDPATRTFQAIRIHLNAELDELEQGLAAAERVLRPGGRLAVVSFHSIEDRIVKRFLRDRSGATPAGSRHLPDARAGGPRPSFEAVAKPVRAGEAELARNPRSRSATLRVARRTAAAPWGTAPKKEGRQG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_SACEN
Sequence: MAMTSAVKDELSRLSVTKTCCRRSEVSSLLRFAGGLHIVAGRVVVEAELDSGSSARRLRKEIHELFGHQSDVHVITSGGLRKGTRYVVRVVKDGEGLARQTGLLDPRGRPVRGLPAHVVSGGACDSESAWRGAFLAHGSLTEPGRSSSLEVTCPGPEAALALVGAARRLGIQAKSREVRGADRVVVRDGDAIGALLTRLGAHSSVLAWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERALELLGPTAPDHLLVAGKLRLSHRQASLEELGQLAEPPMTKDAVAGRIRRLLAMADKRARELGLPDTESAVTAEMLEA
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: NADA_ECODH
Sequence: MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNHEVHVDERLRERALVPLNRMLDFAATLRG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_STRR6
Sequence: MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQVYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAVMELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTVEMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREEILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAAITQEITEIVAGASALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PRTZ_CLUHA
Sequence: ARRRRSRRASRPVRRRRPRRVSRRRRARRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-Z, Clupeine-Z.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CH602_PROM0
Sequence: MAKRIIYNEQARRALERGIDILAESVAVTLGPKGRNVVLEKKFGAPQIINDGVTIAKEIELEDHIENTGVALIRQAASKTNDAAGDGTTTATVLAHAMVKAGLRNVAAGANAITLKKGIDKATEFLVGKIQENSKPISDSNAIAQCGTIAAGNDDEVGQMIANAMDKVGKEGVISLEEGKSMTTELEVTEGMRFDKGYISPYFATDTERMEAVLDEPYILLTDKKIALVQDLVPVLEQIAKTGKPLVIIAEDIEKEALATLVVNRLRGVLNVAAVKAPGFGDRRKAMLEDMAVLTNGQLITEDAGLKLENATLDMLGTGRRITINKETTTIVAEGNEQAVKARCDQIKKQMDETDSSYDKEKLQERLAKLAGGVAVIKVGAATETEMKDKKLRLEDAINATKAAVEEGIVPGGGTTLAHLSPILKEWADKNLEGEELIGANIVEASLTAPLMRIAENAGSNGAVIAENVKTKPFNDGFNAATGEYVDMSSAGIVDPAKVTRSGLQNAASIAGMVLTTECIVADLPEKKDSAAPAGAPGMGGDFDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_XYLFA
Sequence: MNHTSDTALLIVNLGTPEAPTAAAVRRYLGEFLSDRRVVSIPPLFWKPLLHMVILPIRGPRSASKYAKVWLQEGSPLSVYTRRIAEGLTQHLPDWRVAWAMRYGAPALTKALDALQAQQVRRIVILPLYPQYSTTTTASVQDVVEAWCKRTPQVQVECIQDYAEDSAWVAAVAASIRRHWQAHGRSEKLMFSFHGLPQRVANNGDPYPQRCQVSASLIAAALDLNESEWVLGYQSRFGAERWLQPYAEPTLWALAESGIRRFDLVCPGFSVDCLETLEEVALGFSETLAARGATMRYIPCLNDDPAHVQALAGLAQRALL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNZ5_CAEEL
Sequence: MSVQNGFTAKIIRFVPHFVALRLSWTHNDLKAEGLEQFVEECLPAIRENNPQVKYFLQRSYTTCDPFVVGEYSWLRHRKKRVNWKSKEQVLSMIEEMSIGGDYREGYKRGVNRRLPRGQELWDTETMGHDVFHVTSKWKADIPEEDELPITAKTHPNFTYRKY
What are the official names of this protein?
Uncharacterized protein T09A5.5.
Protein: FLOA_BACTN
Sequence: METSLYLPIVLIVGGIIFLILFFHYVPFFLWLSAKVSGVNISLIQLFLMRIRNVPPYIIVPGMIEAHKAGLKNITRDELEAHYLAGGHVEKVVHALVSASKANIELSFQMATAIDLAGRDVFEAVQMSVNPKVIDTPPVTAVAKDGIQLIAKARVTVRASIKQLVGGAGEDTILARVGEGIVSSIGSSENHKSVLENPDSISKLVLRKGLDAGTAFEILSIDIADIDIGKNIGAALQIDQANADKNIAQAKAEERRAMAVASEQEMKAKAQEARAKVIEAEAEVPKAMAEAFRSGNLGIMDYYRMKNIEADTSMRENIAKPTTGGTTNQPLSK
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Membrane raft; Single-pass membrane protein.
Protein: CO1A1_NOTSH
Sequence: SYGYDEKGGVSVPGPMGPSGPRGLPGPPGPGPQGFQGPPGEPGEPGSGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGASGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGPPGPKGNSGEPGAPGSKGDTGAKGEPGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGNGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGAPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGPPGPIGNVGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKEGGKGPRGETGPAGRPGEVGPPGPPGPGEKGSPGADGPAGAPGTPGPQGISGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGSSGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGPKGDRGETGPGPPGAPGAPGAPGPVGPAGKNGDRGETGPAGPAGPAGPAGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPAGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPG
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: RRF2M_ASHGO
Sequence: MPWCNTRLRTCGASPKIFLRRVRCPVLLHNWTIGRVSSVSKMILRFLRSYSKRVDITRVRNIGIIAHIDAGKTTTTERMLYYSGKIKRIGDVDHGDTITDFLPQERSRGITIQSAAISFNWRDNYTVNLIDTPGHADFTFEVIRSLRVLDGCVTILDAVAGVEAQTEKVWKQAAEIPKVCFINKMDRVGAGYSRAVKELIVKLKTRVLLLNTPLFAARDSSADPVFVGVLDAVNGQLLEWDPEDPDKISAKAVDKECAHYEELVSAREALVETLSEVDEKLVEYFLGEADGDYMKVPVEVLNESIRRATLSQYAVPVLCGASFKNIGVQPLLDAVVDYLPSPAEARLPELSNKDLPVQHHLKNGLLVNKNANLCLALAFKVTTDPIRGAMVFIRVYSGVLNSGHTVYNSSTGVKFKLGKLIKMHANVAEDIKSLHPGDIGVLAGANVADHVRTGDTIVAHCTSKDGIRSFKKAELALRIHPIDIPPPVFSAAVEPRTLGNKKAMDESLTQLTREDPSLVIVRDEETGQTVMNGMGELHLEIAADRLLNEFKAPVRVGKVAVSYKETINTATETKHSETDDGYSFELEVRQYNEEDKVLFSNGWYPLGSDNNYLVIDPNPRFNEDNWPFPLKYEAFVNSIISCCIVALQRGGKTAGFPLHSCVIHVKRWRLPLDCAAAASILLTVRPLIISALTSLPTSAFSILEPIMNVEVTVQQQDLGSVVQDLTGARKANILSIDDEHHWADAAVTDKDVHLFHDIAEKQYLPPDSTVFQAKLNKEGQTGKIVKAHVPLKEMVSYMNKLRMLTKGRGSFHMSYLGMERASSDRVDGILEDADL
What is the function of this protein?
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.  Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
What are the official names of this protein?
Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PURP_PYRIL
Sequence: MSVLKRYDLEKLAVATVASHTALQILRGAKKYGFRTIAIAGRADVAEFYQQFNFIDEVWTVDFRNFVKAAEKLVEANAVFIPHGSYVEYVGWRQALEAPVPTLGCRELIKWEADQYKKMELLQRGGIPTSRVYKTPEEVDRPVIVKLFGAKGGRGYFLARDREELRRRLAGLSDYIIQEYVFGVPAYYHYFSSPVYGRVEVFGADIRYESNVDGRTFGWVEPTFVVVGNLPLVLRESLLPTIWKYGVQFAKAVEEVVGCRLAGPYCLESIIRDDMSISVFEFSGRIVAGTNIYMGYGSPYSVLYFDRPMDMGERIAHEIREAARRGRLEDLFT
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.