PharMolix/UniProtQA huggingface dataset:
Protein: YIIE_ECOL5
Sequence: MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQQFPVRKAKGGRQRGETVVVDDQCKEHKE
What are the official names of this protein?
Uncharacterized protein YiiE.
What is the protein family that this protein belongs to?
Belongs to the YiiE family.
Protein: RL5_HYDCU
Sequence: MARLQKIYNDQVVPALVEKFGYKSVMQAPKLTKITINMGVGEAIGDKKILDNAVSDMEAITGQKPVKTLARRSVASFKVRDGYPLGCKVTLRGAKMYEFLDRLINVALPRVRDFQGVKGNAFDGRGNYNLGVKEQIIFPEIEFEKVDKIRGMDINFATTASTNEEAKALLEAFNFPFKKQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GCS2_BRASB
Sequence: MDPRILERLRLGLSDDERRLVIRSATGGEDVTEYSFGIEEEYFLADARTLDVAIRTPDDLFEAANWSTGGQAMREMLQAQIEVATNVHVDSRDAREELKFLRREVASVAGQYGLTILACSTHPTAMWRSSQPTPRPRYAEMMEDLRIVGQRNMLCGMHVHVQLPDSERRFAVMRAMIPYIPVFIALSASSPFWNSRETGLKGYRLAAYDELPRTGLPELFTSKPEYDRYVAALTRSGVMPDESHVWWAMRPSLRHPTLELRAPDVCTSVDDAVAVASLYRALARHLYLHPDLADAVGNVERAIAVENKWRAQRYGTDCLFVAEEGPVTGQEILNRMIADIAPHAEALDCLAEVERCRTIMQFGSSADYQLQAYRESGGELSAVLRWIEVATVSRSDPPRTHAPVEPAQ
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: GLTB_HORVU
Sequence: CGVGFVANLSNEPSFNVVRDALTALGCMEHRGGCGADNDSGDGAGLMSGIPWDLFDDWASKEGLVPFERTHTGVGMVFLPQNENSMEEAKAAVEKVFTDEGLEVLGWRPVPFNLSVAGRNAKETMPNILQIFVRIAKEDDADDIERELYICRKLIERATKSASWADELYFCSLSSRTIIYKGMLRSEVLGQFYLDLQNELYKSPFAIYHRRFSTNTSPRWPLAQPMRLLGHNGEINTIQGNLNWMRSREATIQSPVWRGRENELRPFGDPKASDSANLDNAAELLLRSGRSPAEAMMMLVPEAYKNHPTLSVKYPEVIDFYEYYKGQMEAWDGPALLLFSDGRTVGACLDRNGLRPARYWKTSDGFVYVASEVGVIPMDESKVVMKGRLGPGMMITVDLETGQVLENTEVKKNVASAKPYGTWLQESTRSIKPVNF
What are the official names of this protein?
Ferredoxin-dependent glutamate synthase, FD-GOGAT.
What is the protein family that this protein belongs to?
Belongs to the glutamate synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PHS_PARDP
Sequence: MTGLDRERIVDGAPALSAEELQAALAGLPGWQLAGDGKSICREWRFKNFKQAAQLANLAAWQAEAAGHHPDIAFGWGHARVSYSTHSAGGVSRNDLIMAARLDAATG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RL1_RHOPT
Sequence: MAIGKRLKKIREGIDRTKLYPLDEAVKLVKERAISKFDETIEVAINLGVDPRHADQMVRGVVMLPNGTGRTVRVGVFARGAKADEAKAAGADVVGAEDLVEQVQAGNINFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKIGTVTMDVAGAVKGAKGGSVEFRVEKAGIIQAGVGKASFDADKLVENIKALADAVNKAKPTGAKGTYIQRVAVSSTMGPGVKVEPGTVH
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PCDP1_HUMAN
Sequence: MAVVKTPSRGLKNAKEPFNNASPHLLKNLVEEPKKRKEVPNHLLESKVYAKLVNNKVIQARPGIIHFGGYQVEKQHQQILHLVNVSNEDTRVHILPPQTKYFEINYVRKEHHLVPGLSLTVTVTFSPDEWRYYYDCIRVHCKGDDTLLVPIHAYPVMNSLDFPSFINLSNVLLGESKTYVIPLQCSCPVDFEFYITLIQSHQAFAIEPTSGIIPANGKMTVTIKFTPFQYGTAQIKMQLWISQFNSQPYECVFTGTCYPNMALPLEEFERLNTLSKKVNVPPEKAMMHINFHRPPAKPKPQKVKEIEYQNLRFPVDLSNPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDIHEEMENHLKWQVHLGKDPMSFKLKKELTEEWQKACAKYKLDRGDPILDEEFQRLKTEVSHKRVVRNQEEKIKEFHPTFDPLINNTWLSRSRAQKRFQQVARKVMIQGRLFNMLSAVREMDKESILRKIGQAKQSIAQEANFFKFFLRRISQDDYTSRFSVSPKEVLPFAFPDCSPPQDSNELAPDGLGLVPIKSSEVQIKQSYSFFNLQVPQLYKIKRYQPFSVHKSSTSYRPQKLARALKQGAEDEVTTITALPKQDSTTQLSGKTSVLSMKPPEALAMSLDYDPLYVFNPNPGLFAVMHPLTYAETLIDYHLCSHPKYKFTKESRHGSSIPVTQKQFLHHTDIIPGIMHWKSFQSLVLSSLPDPSKMETTKSCDSFNSFMLPIDVPAILDALPEEDRLETVERELCEQNVEVMLTPEMIKVEFPMLNYKDIRKEKEVKDQAQPAEKAGEKLLEEMRNLRGKALNTYLILE
What is the function of this protein?
May play a role in cilium morphogenesis.
What are the official names of this protein?
Cilia- and flagella-associated protein 221, Primary ciliary dyskinesia protein 1.
What is the protein family that this protein belongs to?
Belongs to the PCDP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm. Cytoplasm, cytoskeleton. Note=Localizes to the manchette in elongating spermatids in a SPAG17-dependent manner.
Protein: FA9_PIG
Sequence: YNSGKLEESFVRGNLERECIEEKCSFEEAREVFENTEKTNEFWKQYVDGDQCEPNPCLNGGLCKDDINSYECWCQVGFEGKNCELDATCNIKNGRCKQFCKTGADSKVLCSCTTGYRLAPDQKSCKPAVPFPCGRVSVSHSPTTLTRAEIIFSNMDYENSTEVEPILDSLTESNQSSDDFIRIVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKVTIYSNMFCAGFHEGGKDSCLGDSGGPHVTEVEGTSFLTGIISWGEECAVKGKYGIYTKVSRYVNW
What is the function of this protein?
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
What are the official names of this protein?
Coagulation factor IX, Christmas factor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPPP_FLAPJ
Sequence: MNYIQAIILAIIEGITEFLPVSSTGHMIIASSFFGIAHEDFTKLFTIVIQLGAILSVVVLYFKRFFQTLDFYFKLLVAFIPAVVLGLLFSKKIDALLESPVTVAVSLLVGGIILLKVDDWFNNSSETEITYLKAFKIGLFQCIAMIPGVSRSGASIVGGMSQKLARTSAAEFSFFLAVPTMLGATLKKCYDYYKDGFILTHDQINILIIGNIVAFLVALLAIKTFIGFLSKNGFKVFGYYRIVAGIVLLLIHFFIHPLTLI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTH_LEGPH
Sequence: MVIKLIVGLRNPGSAYEQTRHNAGAWLVTALAQRHNSHFKIDKKMQAELTEIDINNHPCRLVLPLTFMNHSGQTTRIISQFYKIEPGEILIVHDELDLPVGRIKLKTGGGHGGHNGLRDITAQLGTGEFHRLRIGIGHPGHKDLVHQYVLSRPSMHDRQQIYDAIDRGIAIIPIVLSGDMARAMNQVNA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1AC_PORPU
Sequence: MGKEKQHVSIVVIGHVDSGKSTTTGHLIYKCGGIDKRAIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETDKYNFTIIDAPGHRDFIKNMITGTSQADLAILVIASPPGEFEAGISQNGQTREHALLAYTLGVKQMIVACNKMDDKNVNWSKERYEEVSKEMDLYLKKVGYNPPKVPKVPTSGWTGENLFERTGGDHALGKWYKGPCLLEALDACDPPKRPVDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPSGLSTEVKSVEMHHEALTQAGPGDNVGFNVKNVSVKDLKRGYVCGDSKNDPPKGCASFNAQVIILNHPGEIHAGYAPVLDCHTAHIACKFSELILKMDRRSGKKLEDSPKMIKSGDAAMVKMVASKPMCVEAFTSYPPLGRFAVRDMRQTVAVGVIKSVEKKEVEGKMTKSAAKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha C, EF-1-alpha C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMTR2_MOUSE
Sequence: MSKRRKLPARQPACLETFSPDVLNDVSELFAKSFSYRKPLDNEWQLPAPTESFSCGHLEFRALLDLKNSLNEVKNLLSDKKLDEWHRHTAFTNKAGKIISHVKKAVNAELCTQAWCKFQEILCSFPLIPQEAFQSGRLNSLHLCEAPGAFIASLNHYLKSHRFPCEWSWVANSLNPYHEANDNLRMITDDRLMANTLHCWYFGPDNTGDIMTLKYLTGLQDFLSGMSPIHLVTADGSFDCQGNPGEQEALVSSLHYCEAVTALITLGDGGSFVLKMFTLFEHCSVNLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLRYKGREAVQPLLSRMVLNFGTEMTRKALFPHHVIPKSFLERHEECCTFFHRYQLETISENIRLFESMGTGEQERLNNLRDCAVQYFMQKFQLKPLSRNHWLVKKSNIGCSMNTKWFGQRNKYFKTYNERKMMETLSWKDKVAKGYFNSWAEEHTVYHPGQNSLLEGTASSLEYQSWQVLEGKKLPKVKCSPFCDGEILKTLNEAIEKSLGEALSVDAKVSSKQQYRCCPVFSEESVLSELLRLTKCLPDEQGAEPSGPVKCLLVGSPAVCDLQMPAPLEIQLVESVELTAFSCSLLHDGDPAYQHLFLDCLLHSLRRLHRGDVMVLPILSCFTRFMAGLTFVLHGCFRFITFSCPTSLEPLRTCAVLLCIGYQNLPDAVFQFLQNVHDLLSKLLHPSAPRQILQFLPMEALLQGTLLDFLWDLNAAIAKRHLHLIIQGERDQAIGSLEL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs.  Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2).  Recognizes a guanosine cap on RNA independently of its N(7) methylation status.  Display cap2 methylation on both cap0 and cap1.  Displays a preference for cap1 RNAs.
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2, Cap methyltransferase 2, Cap2 2'O-ribose methyltransferase 2, MTr2, FtsJ methyltransferase domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MAD2_YEAST
Sequence: MSQSISLKGSTRTVTEFFEYSINSILYQRGVYPAEDFVTVKKYDLTLLKTHDDELKDYIRKILLQVHRWLLGGKCNQLVLCIVDKDEGEVVERWSFNVQHISGNSNGQDDVVDLNTTQSQIRALIRQITSSVTFLPELTKEGGYTFTVLAYTDADAKVPLEWADSNSKEIPDGEVVQFKTFSTNDHKVGAQVSYKY
What is the function of this protein?
Central component of the spindle assembly checkpoint which is a feedback control that prevents cells with incompletely assembled spindles from leaving mitosis.  Thought to be recruited to unattached kinetochores by MAD1.  During checkpoint activity, MAD2 is relayed from the MAD1-MAD2 complex to the mitotic checkpoint complex (MCC).  MCC and presumably the MAD2-CDC20 subcomplex inhibit the ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) by preventing its activation by CDC20.
What are the official names of this protein?
Mitotic spindle checkpoint component MAD2, Mitotic MAD2 protein.
What is the protein family that this protein belongs to?
Belongs to the MAD2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAD_MYCBT
Sequence: MTGAVCPGSFDPVTLGHVDIFERAAAQFDEVVVAILVNPAKTGMFDLDERIAMVKESTTHLPNLRVQVGHGLVVDFVRSCGMTAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNRRLRDRLNTERT
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_MESHJ
Sequence: MNVSFSIAPYFFKERRAKLNSFRKRKVEIVAEIDSLLKNSSSLAIVEYRGLTVNELEQLRKEFKSAGVLSKVYKNRLFKIAAENNGYLDLQTDLVGPNLFAFGTTDAIAPAKIIAKNAKEQPLLILKGGIYDNQVVSAAENALISALPSYTEALTMLASGLQSPLKQLAFGLKLLIDEQKITA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: LFTR_NITWN
Sequence: MSRETASSEITPELLLRAYACGIFPMAESVDDPTLFWVEPKMRGVVPLESFRIPSRLARTVRSDSFTVTVDTAFDAVINGCAAPQPGRNNTWINHRIRELYIGLHELGHCHSVEVWRDNELAGGLYGVRLGRAFFGESMFHVVRDASKVALVHLVARLIAGGFVLLDTQFVTDHLRGFGAIEIPRRRYRALLDVALEGRADFGALPLDRPVPGAEALKAIADRSS
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFD_HAEIE
Sequence: MFKMVSSPHTHSGKLTARIMLWVILAMMPAFFTQIYYFGFGVLLQSALAIGTAIIAEFIAIKLRGKKPLNYLSDFSVALTALILAMAIPPYAPYWVIIIGTLCAVLLGKQVYGGLGQNPFNPAMIGYVILLISFPLQMTTWMPPINLLQEPPTFSDAFSLIFSGLTTDGFTLSQLTHNIDGITQATPLDSAKIFYKSHNQLSDFYELIKLPIFMGNGTDFAQGWWQINVAFLAGGIFLILKRIIHWQIPVAMLVTFFCLATATAFTGFTHLSAISQLVSGAMMFGAFFIATDPVTASITPRGKIIFGALVGLFVYLIRYHGNYPDGVAFAILLSNICVPLIDHYTRPRVSGYPTKGRK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THI4_FUSO4
Sequence: MAPPAAVSPPSRSAELATSTKLPVMSKNINTKTVEEMLGQWDDFKFAPIRESQVSRAMTRRYFQDLDNYAESDIVIIGAGSCGLSAAYILGKKRPDLKIAIIEASVSPGGGAWLGGQLFSAMIMRKPADAFLREVGVPYEDEGNYVVVKHAALFTSTIMSKVLQMPNIKLFNATCVEDLITRPSEEGVRIAGVVTNWTLVSMHHDDQSCMDPNTINAPLIISTTGHDGPMGAFCVKRLVSMQRIEKLGGMRGLDMNLAEDAIVKGTREIVPGLIVGGMELSEVDGANRMGPTFGAMALSGLKAAEEALKIFDTRKKQNDL
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Stress-inducible protein sti35, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ENV_XMRV3
Sequence: MESPAFSKPLKDKINPWGPLIIMGILVRAGASVQRDSPHQVFNVTWKITNLMTGQTANATSLLGTMTDTFPKLYFDLCDLVGDNWDDPEPDIGDGCRSPGGRKRTRLYDFYVCPGHTVLTGCGGPREGYCGKWGCETTGQAYWKPSSSWDLISLKRGNTPKGQGPCFDSSVGSGSIQGATPGGRCNPLVLEFTDAGKRASWDAPKTWGLRLYRSTGADPVTLFSLTRQVLNVGPRVPIGPNPVITEQLPPSQPVQIMLPRPPRPPPSGAASMVPGAPPPSQQPGTGDRLLNLVEGAYQALNLTSPDKTQECWLCLVSGPPYYEGVAVLGTYSNHTSAPANCSVTSQHKLTLSEVTGQGLCIGAVPKTHQALCNTTQKTSDGSYYLASPAGTIWACSTGLTPCLSTTVLNLTTDYCVLVELWPKVTYHSPNYVYGQFGKKTKYKREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATKQFEQLQAAIHTDLGALEKSVSALEKSLTSLSEVVLQNRRGLDLLFLKEGGLCAALKKECCFYADHTGVVRDSMAKLRERLNQRQKLFESGQGWFEGLFNRSPWFTTLISTIMGPLIVLLLILLFGPCILNRLVQFVKDRISVVQALVLTQQYHQLKSIDPEEVESRE
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the virion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: APT_FRAT1
Sequence: MNLDFIKSKIAAVPDFPKPGIMFRDITPLLADPQGLRKTAEAMAQELKNKGIQPTIVAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRATYSVKYDLEYGSDSLEIHQDAFKVTDEVLVVDDLLATGGTAKATVDLIEKTQAKVAGLIFVMELDGLGGREVLAGYNVSALIKF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODPA_HUMAN
Sequence: MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ISL2A_ONCTS
Sequence: MVDIIFNSSFLGDMGDHSKKKSGIAMCVGCGSQIHDQYILRVAPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCANCNIGFCSSDLVMRARDNVYHMECFRCSVCSRHLLPGDEFSLRDEELLCRADHGLLMEQASAGSPLSPGIIHSRSLHIADPVSVRQPPHRNHVHKQSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIFMKQLQQQHHSDKTNLQGLTGTPLVAGSPIRHDNTVQGNPVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSMGNSSGSDVTSLSSQLPDTPNSMVASPVDT
What is the function of this protein?
Binds to one of the cis-acting domain of the insulin gene enhancer.  May be involved in subtype specialization of primary motoneurons.
What are the official names of this protein?
Insulin gene enhancer protein ISL-2A, Islet-2A.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRA25_CAEEL
Sequence: MNELIDGPKCASEGIVNAMTSIPVKISFLIIATVIFLSFYFARLAILALLRNNIFSNSTQRILLVCLVNSVFHQAATLEIRIHQVYRSFVYASDPCSLLFHFTECEVELYFYYLTNYFSTYSVFSLTFDRLISHYNPRFYFSQQNFVSNTLLIIQCLLSFGTYYVGLYGVPPFGYVSICYYTPKYAVNFLKINDFRTVVMVFCIIVIIFVYYLSVRSEKQIQRTSYSPGERYWAYENVETSQSVCILIVLQFACILMSSYGVNYIRSKESMMSEEDFHTLAPFFAGVTYASLCLPLVIYFKTKLTIRNRRIRIAVMTSMYGDVGDHMNRLKKSWE
What are the official names of this protein?
Serpentine receptor class alpha-25, Protein sra-25.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sra family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1712_LACPL
Sequence: MPIVHIDLIAGRSQEQLKNLVKDVTDAVSKNTGAPAEHIHVILSEMQKNRYSVGGVLKSDEEAE
What are the official names of this protein?
Probable tautomerase lp_1712.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: ZB10P_HUMAN
Sequence: MVVREASAAQASLSQVLPQLRYLHIFLEQVHTHFQEQSVGERGAAIQLAEGLARQLCTDCQLNKLFYREEFVLATLLDPCFKGKIEAILPWGPTDIDHWKQVLVYKVKEIRVSEYSLNSPSPLQSPRGLCVDPTRVAKSSGVEGRSQGEPLQSSSHSGAFLLAQREKGLLESMGLLASERSGGSLSTKSHWASIIVKKYLWENETVGAQDDPLAYWEKKREAWPPSICLTPHRSLL
What are the official names of this protein?
Putative protein ZBED10P, ZBED6 C-terminal-like protein, zinc finger BED-type containing 10 pseudogene.
Protein: ACB1_SPHPE
Sequence: MSMVRSFFDGLTNVLSGAGTSVDKRVHARYGLNIVDQHQVEASYRTSWLARKIVDMPAHDMTREWRDWKADGELIGKIEAEEKRLCLRERVTQAIVLGRLGGGAIYLGIKGDDPSQPLAVEHIRPGQLSYIAVFSRWQLTIGQEVSDPEDALFGGPDYFQITSIANKVGVRIHPSRMVIFKGAHVMRGIGSQWEDAFWGDPIYQAVGDAIRNADSAQNSFASLIDEATYDVIGIPGLMERLSQPGGDAQLSKRLDAARQGKSNHRAIILDSGEGGKDAETWVTRQVTWAGMPELMAAFLQTVAGASDIPYTRLLGTSATGMSATGEGDKNDYLSSIATKQETMLRPNMVRIDAVMLRSAGIKDELWFDWSPLFEMGEKERAALDKLKADTAKVWGDSGLVPIDALAKGAQNLLTEDGTYPGLDEELKKAEAIVAPDADVAPVVANPDDLGLTSEAKPKPLLKIVGDAAPRPLYVNRPLLNAAEFIAWAKAQGFKTTTPADDLHVTILYSKTPVDWMKMGTDGWGSDAKGNLDVAPGGARIVEPLGDKGAVVLLFTSSSLSWRHEEMVRNGASHDFDEYQSHVTISYDASDVDLSKVEPYRGVLKFGPEVFTEIVEDWKPTGGEA
What is the function of this protein?
Counteracts or regulates the endogenous CBASS antiviral defense system.  Phosphodiesterase that enables metal-independent hydrolysis of the host cyclic di- and trinucleotide CBASS signals such as 3'3'-cGAMP, 3'3'cUA, and 3'3'3'-cAAA.
What are the official names of this protein?
Anti-CBASS protein Acb1, Acb1.
What is the protein family that this protein belongs to?
Belongs to the anti-CBASS protein Acb1 family.
Protein: NUON_YERPN
Sequence: MTITPQQLIAMLPLLIVGLTVVVVMLSIAWRRDHFINATLTVIGLNLALLSLYFVGQVGPMDVTPLMRVDGYSMFYTGLVIIASLATSTFAYPWLVGYPDNREEFYLLVLIAALGGILLASANHLASLFLGIELLTLPLFGLIGYAYRQKRSLEASIKYMLLSAAASSFLLFGMALLYAESGSLSFVGLGQSLSDSMVHQPLILAGLGMMIVGLGFKLSLVPFQLWTPDVYQGAPAPVSTFLATASKIAIFAVVMRLFMYAPAADSEAVRLVLSIIAVASILFGNLMAISQTNIKRLLGYSSIAHLGYLLIALVAVQTHELALPLETIGVYLAGYLFSSLGAFGVVSLMSSPYKGPDAESLFSYRGLFWHKPILSAVMTVMMLSLAGIPMTLGFIGKFFVVAMGVSANLWWLTGAVVLGSAIGLYYYLRVTVSLFLSPPQSLVRDTPSNWALTAGGVVVLISAILVLVLGIYPQPLITLVQMAQPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HISZ_AQUAE
Sequence: MKTSLISGERFYSLEESNLVKEIFKKAVKIFEAFGYDYINLSHFEPYEFQELTFGEGSKEAITFKDSYTKESFGLRLDFTTQVVRTISHLRNVKLPERVYYFGKVFSLDRRGFEKLQTGVELIGEKSILADFEVIQVLTEFLKSLGLKDLKVILSHAGIVRKVADEREELLRAFSERNLEALKEVLGNDIKFFVEVSKNPEVLNFLEKYDLEKEKEELLELGKLLEEFGIDYAYDLGEVRNFPYYTGVIFEIYELKSGKALAGGGRYDNLSKIYGKEYPATGGAVYLERLLDILPKNVEKKDYFVIDKTKKRLGLKLADVLREKGKKVGMEIVKERGLEHSLIYAFDKGFKEVLLVEDEIVKVYTTPKDYVVMKIREFLDLIE
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.