PharMolix/UniProtQA huggingface dataset:
Protein: MSHB2_FRAAA
Sequence: MFVHAHPDDEVISTGIALASYAAAPDTSVTLVTCTLGEEGEVLVPELINLRADRGDQLGGYRIGELAGSCAALGITDQRFLGGPGRWRDSGMIGTPANDHPRSLWRADLAEATAELVRIVRDVRPHVLVSYDSNGGYGHPDHIRAHQVTARAFTDAADPAFAPGTGEPWQVAKRYETAMPRSRAVAGFELFHDSADRNNPFAGLKSVDDLAMTLVDDADITAEISAPEFFDAKIAAMRAHRTQMAVDGFFFALADGIGQRAWGVEHFVLAAGTRGPGDGPDGRERDLLAGVAF
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 2, GlcNAc-Ins deacetylase 2, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 2.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: NADK_PSEPW
Sequence: MEQFRNIGIIGRLGSSQVLDTIRRLKKFLLERHLHVILEDTIAEVLPGHGLQTSTRKLLGEVCDLVIVVGGDGSLLGAARALARHNIPVLGINRGNLGFLTDIRPDELEEKVAAVLDGHYLVENRFLLQAEVRRHHEAIGQGDALNDVVLHPGKSTRMIEFEIYIDGQFVCSQKADGLIVATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHTLSGRPIVVDGNSELKIVVSKDLQIYPQVSCDGQNHFTCAPGDTITVSKKPQKLRLIHPLGHNYYEVCRTKLGWGSRLGGRDD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APH1C_MOUSE
Sequence: MTLPVFFGCAFIAFGPAFALYLFTIATDPLRVIFLIAGAFFWLVSLLLSSMFWFLVRVITNNRDESVQNYLLIFGALLSVCIQELFRLAYYKLLKKASEGLKSINPEEDIAPSMRLLAYVSGLGFGIMSGVFSFVNTLSNSLGPGTVGIHGDSPQFFLNSAFMTLVVIMLHVFWGVVFFDGCEKNKWYTLLTVLLTHLVVSTQTFLSPYYEVNLVTAYIIMVLMGIWAFYVAGGSCRSLKFCLLCQDKDFLLYNQRSR
What is the function of this protein?
Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (amyloid-beta precursor protein).
What are the official names of this protein?
Putative gamma-secretase subunit APH-1C.
What is the protein family that this protein belongs to?
Belongs to the APH-1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UPP_THEPX
Sequence: MYKNVFVIDHPLIQHKISLIRDENTGSKEFRELVEEIAMLMAYEVTRDLPLEEIEVKTPVAVAKTKVIAGKKLGIIPILRAGLGMVDGMLKLIPAAKVGHIGIYRDPETLKPVEYYCKLPSDIAERDLIVVDPMLATGGSACAAIHFLKERGAQNIKLVNLIAAPEGIEAVHRDHPEVPIYVASIDQGLNEHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: WHIA_CLOBB
Sequence: MSFSSKVKGEICRYVDMCKEDALAEISAIMKVSGTIAFSGSGLSFKMTTENPASARLIFTLLKEHFNIHSKLMVKKSNSLKKNNIYMVVISEDMGVRELLYETGILQDIDGIMNLNYRINKSMIETEENRRAYIRGAFIGGGSISNPERTYHLEFVTHSEEYAIDLKDIINTFGLNSKVIQRKSSHIIYIKEGEQIVDLLNIIGAHASLLELENIRIMKEMRNNVNRLVNCETANLSKTVNAAVRQVESIRLIQNKIGLQRLPQNLREVAELRLNYPDESLKELGQMLDPQVGKSGINHRLRKIEKIAEELRTGN
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: SNTG1_MOUSE
Sequence: MDFRTTCEETKTGVCLLQDGNQEPFKVRLHLARDLLMLQEQDVLCVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFLKLPVNEDCACAPSDQSSGTSSPLCDSGLHLNYHPNNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHARFSQYVPGTDLSRQNESQVVAVDGVCSGILQCLSAEDCMDWLQAIASNISNLTKHNIKKINRNFPVNQQIVYMGWCEAREQESLQDRVYTPVFLALRGSCLYRFLSPPVTTWDWTRAEKTFSVCEIMCKVLKDSDLLDRRKHCFTMQSECGEDLYFSVELESDLAQWERAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGFICFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDTKQIEAKELEFSNLFAVLHCIHSFFAAKVACLDPLFLGNQAATTAAVSSASTSKAKHLA
What is the function of this protein?
Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins.  May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.  May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation (By similarity).
What are the official names of this protein?
Gamma-1-syntrophin, G1SYN, Syntrophin-4, SYN4.
What is the protein family that this protein belongs to?
Belongs to the syntrophin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Mainly cytoplasmic and weakly nuclear.
Protein: CLSA_YERPY
Sequence: MTTFYTVISWLSVFGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLSFGELHLGKRRAERAKAMWPSTARWLSELKECQHIFANSNSEVASPLFQLCERRQGINGVKGNQLQLLTTTDDTLKALVRDIELARHNIEMVFYIWQPGGLVDQVAESLMAAARRGVHCRLLLDSAGSKQFFRSPYPAMMRNAGIEVVEALKVNVFRMFLRRMDLRQHRKIVLIDNYVAYTGSMNMVDPRFFKQDAGVGQWIDMMARMEGPVATTLGIVYACDWEIETGKRILPPPPDANIMPFEEETGHTIQVIASGPGFPEEMIHQALLTAVYAAREQLIMTTPYFVPSDDLLHAICTAAQRGVDVSIIVPRENDSMMVRWASRAFFTELLNAGVKIYQFEGGLLHSKSVLVDGQLSLVGTVNLDMRSLWLNFEITLVIDDDGFGADLAQVQDDYIARSALLDGELWNKRPLWHRVTERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FAEB1_ASPTN
Sequence: MKISYFFVASLSYVSVARASQSFEERCTDFRDSINSLPNVQATIVEYVAGSQNVSLPDNDPSCNQSSQFVTADICRAAMVVKTSNSSQIVMEAWFPRNYTGRFLATGNGGFGGCIRYPELDYTTRLGFAAVATNNGHNGTSAEAFLNSPEVLRDFADRSIHTAAKVGKELTKRFYAEGFRKSYYLGCSTGGRQGFKSVQQYPHDFDGVVAGAPAVHEVNLISWAGHIYEITGNKSEETYLPPALWNIVHSEVMRQCDGLDGAQDNLIEDPDLCHPTFENIMCPSDNKSNNGSLSCITEAQANTVIQLMSPYYNTDGSMLFPGMQPGSETVSSALLYTGVPTPYAKEWFRYVVYNDTNWDPTTFNIKDAQAALKQNPFNIQTWEGDLSRFQNAGGKIITYHGMQDFLVSSFNSREYYKHVHETMGLAPDQLDEFYRYFRISGMAHCYYGDGASYIGGSAPSAYSDDPEDNVLMAMVEWVEKGIAPEFIRGTKLDQDGHPQYTRKHCRYPRRNVYRGPGSYLDENAWECVL
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
What are the official names of this protein?
Probable feruloyl esterase B-1, Ferulic acid esterase B-1, FAEB-1.
What is the protein family that this protein belongs to?
Belongs to the tannase family.
What are the subcellular locations of this protein?
Secreted.
Protein: ADH2_HORVU
Sequence: MATAGKVIKCKAAVAWEAGKPLSMEEVEDAPPQAMEVRDKILYTALCHTDVYFWEANGQTPVFPRILGHEAGGIVESVGEGVTELVPGDHVLPVFTGECKECAHCMSEESNLCDLLRINVDRGVMIDDGQSRFTIDGKPIFHFLGTSTFSEYTVIHVGCVAKIDPEAPLDKVCLLSCGISTGLGATLNVTKPKKGMTVAIFGLGAVGLAAMEGARMSGASRIIGVDLNPAKHEQAKKFGCTDFVNPKDHTKPVQEVIVEMTDGGVNRAVECTGNADAMISAFECVHDGWGVAHKEAVFKTHPMNFLNERTLRGTFFGNYKPRTGLPGVVDMYMRKELELDKFITHSLPFSQINTAFDLMLRGEGLRCVIRSEE
What are the official names of this protein?
Alcohol dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_SALPB
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFNESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGPNAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSQAKGVYIKKVSISTTMGAGVAVDQAGLSASAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ISPE_PSEAE
Sequence: MSVRLSLPAPAKLNLFLHILGRRDDGYHELQTLFQFLDHGDELHFEARQDGQVRLHTEIAGVPHDSNLIVRAARGLQEASGSPQGVDIWLDKRLPMGGGIGGGSSDAATTLLALNHLWQLGWDEDRIAALGLRLGADVPVFTRGRAAFAEGVGEKLTPVDIPEPWYLVVVPQVLVSTAEIFSDPLLTRDSPAIKVRTVLEGDSRNDCQPVVERRYPEVRNALILLNKFVSARLTGTGGCVFGSFPNKAEADKVSALLPDHLQRFVAKGSNISMLHRKLETLV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CUE3_CONIM
Sequence: MGVFRCCLAAALVVVCLSRMGGTEPLESNHEDERRADDTSGDDCVDTNEDCVNWASTGQCEANPSYMRENCRK
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Im14.3, Conopeptide im031.
Protein: FDHC_METFO
Sequence: MASSFKSPADTAKACVGVAALKEKAPLSNLIVLSFVAGAYIAFGGLLAEVATGGMAAAGWPTGLVKLVFGGVFPVGLMLVVIAGSELFTGNCMYMPMGILQGEASVMGTIKNWVGSWVFNLVGALFVAYVLAYLTGILTAEPWAATAVTIAKTKALGGAQFIAAGKTVTSLSWMQVFWRAIGCNWLVCLAVYLAVASDDVIGKSFGIWFPIMAFVCIGFEHVVANMFFIPVGIFIGGVTWSQFFINNMIPATLGNIVGGAIFVGCIYWFTYLRGTNKAKA
What is the function of this protein?
May act as a formate transporter.
What are the official names of this protein?
Probable formate transporter.
What is the protein family that this protein belongs to?
Belongs to the FNT transporter (TC 2.A.44) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AKH_AUSRA
Sequence: QVNFTPGW
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic hormone, AKH.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBFA_STRT1
Sequence: MGNSFRVDRVGMEIKREVNEILQKKVRDPRVQNVTITDVQMLGDLSAAKVFYTIHSTLASDNQKAQTGLEKATGTIKRELGKNLTMYKIPDLIFIKDESIEYGNKIDEMLRNLERKD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RP65A_DANRE
Sequence: MVSRFEHPAGGYKKIFETAEELNEPLPATVTGRIPSFIKGSLLRLGPGLFEAGAEPFYHLFDGQALMHKFDFSNGQVTYFRKFVKTDAYVRAITEKRVVITEFGTCAYPDPCKNIFSRFFSYFKGVEVTDNCLVNVYPIGEDFYAVTETNYITKVNVDTLETLKKVDMCNYVNINGVTAHPHIERDGTVYNIGNCMGKGASLAYNIVRIPPTQKDKSDPIEKSKVVVQFPSAERFKPSYVHSFGMTENYFVFVETPVKINLLKFLSAWSIRGSNYMDCFESDEEKGTWIHIARKHPGEYIDYKFRTSAMGLFHHINCYEDSGFIVFDLCAWKGFEFVYNYLWLANLRANWEEVKRNAMIAPQPEVRRYVIPLDPFREEQGKNLISLPYTTATATMRADGTIWLEPEVLFSGPRQAFEFPQINYRMVNGKNYTYAYGLGLNHFVPDRICKLNVRTKETWVWQEPDSYPSEPLFVQTPDGVDEDDGILMTIVVSPGAQRPTYCLILNAKDLSEIARAEVEILTPVTFHGMYKP
What is the function of this protein?
Plays important roles in the production of 11-cis retinal and in visual pigment regeneration.  Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity).
What are the official names of this protein?
Retinoid isomerohydrolase, All-trans-retinylester 11-cis isomerohydrolase A, Lutein isomerase, Meso-zeaxanthin isomerase, Retinal pigment epithelium-specific 65 kDa protein homolog A, RPE56a.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Note=Attached to the membrane by a lipid anchor when palmitoylated (membrane form), soluble when unpalmitoylated.
Protein: TRPB_VIBME
Sequence: MAKLNAYFGEYGGQYVPQILVPALDQLEQAFIDAQEDPDFRAEFMSLLQEYAGRPTALTLTRNLTKGTKTKLYLKREDLLHGGAHKTNEVLGQGLVGKRMGKSAIIAETGAGQHGVGSALASALVGLKCRIIMGAKNLERQSPNVFRMKLMAESIPSSVTLKVAVNEALRDWSATETTHYYLGTAAGPHPYPTIVREFQRIIGEETKLQILAREGRLPDAVLACIGGGSNAIGMFADFIDEANVRLIGIEPAGKGIDTHQHGAPLKHGKTGIFFGMKAPLMQDSYGQVEESYSVSAGLDFPSVGPQHAHLNAIGRANYESITDDEALEAFQSIARNEGIIAALESSHALAYAIKMARIDPDKEQLLVVNLSGRGDKDIFTVHQLLEERGAL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PXPA_MACCJ
Sequence: MYIDLNADLGESFGNYKIGNDEAIIPLITSANIACGMHAGDFNVLNQTIELCKAHGTGIGAHPGYPDLQGFGRRNLDMTYDEVENLITYQLGAIDAFCIKHGMKMNHVKPHGALYNATSGNEGLAEAIVNAIYNFNPELKVMGISGGTLVKATEAKGMTAINEVFADRNYTDAGTLVSRKQSNAMIHHQQAAVEHVLRMVRDNQVKTETGKLIDLRADSICVHGDGPEALAFVKAIIETLNNEGIKVQTI
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: SH_BRSVA
Sequence: MNNTSTMIEFTGKFWTYFTLVFMMLIIGFFFVITSLVAAILNKLCDLNDHHTNSLDIRTGLRNDTQSITRAHV
What is the function of this protein?
Viroporin that forms a homopentameric ion channel displaying low ion selectivity.  May play a role in virus morphogenesis and pathogenicity at various stages of the viral life cycle.  Accumulates at the membrane of the Golgi apparatus in infected cells and may facilitate virus release by modifying the secretory pathway.  May enhance host membrane permeability and disrupt cellular ion homeostasis, which can be sensed as damage-associated molecular patterns/danger signals, triggering NLRP3 inflammasome activation and inflammatory immune response.  Also inhibits host TNFA-mediated signaling pathway and may delay apoptosis, allowing time for the virus to replicate.
What are the official names of this protein?
Small hydrophobic protein, Small protein 1A.
What is the protein family that this protein belongs to?
Belongs to the orthopneumovirus small hydrophobic protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. Host Golgi apparatus membrane; Single-pass type II membrane protein. Host endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Present in very small amount in the virion. Detected in lipid rafts of host Golgi apparatus membrane.
Protein: PMPG_CHLTR
Sequence: MQTSFHKFFLSMILAYSCCSLSGGGYAAEIMIPQGIYDGETLTVSFPYTVIGDPSGTTVFSAGELTLKNLDNSIAALPLSCFGNLLGSFTVLGRGHSLTFENIRTSTNGAALSDSANSGLFTIEGFKELSFSNCNSLLAVLPAATTNNGSQTPTTTSTPSNGTIYSKTDLLLLNNEKFSFYSNLVSGDGGAIDAKSLTVQGISKLCVFQENTAQADGGACQVVTSFSAMANEAPIAFIANVAGVRGGGIAAVQDGQQGVSSSTSTEDPVVSFSRNTAVEFDGNVARVGGGIYSYGNVAFLNNGKTLFLNNVASPVYIAAEQPTNGQASNTSDNYGDGGAIFCKNGAQAAGSNNSGSVSFDGEGVVFFSSNVAAGKGGAIYAKKLSVANCGPVQFLGNIANDGGAIYLGESGELSLSADYGDIIFDGNLKRTAKENAADVNGVTVSSQAISMGSGGKITTLRAKAGHQILFNDPIEMANGNNQPAQSSEPLKINDGEGYTGDIVFANGNSTLYQNVTIEQGRIVLREKAKLSVNSLSQTGGSLYMEAGSTLDFVTPQPPQQPPAANQLITLSNLHLSLSSLLANNAVTNPPTNPPAQDSHPAIIGSTTAGSVTISGPIFFEDLDDTAYDRYDWLGSNQKIDVLKLQLGTQPSANAPSDLTLGNEMPKYGYQGSWKLAWDPNTANNGPYTLKATWTKTGYNPGPERVASLVPNSLWGSILDIRSAHSAIQASVDGRSYCRGLWVSGVSNFFYHDRDALGQGYRYISGGYSLGANSYFGSSMFGLAFTEVFGRSKDYVVCRSNHHACIGSVYLSTKQALCGSYLFGDAFIRASYGFGNQHMKTSYTFAEESDVRWDNNCLVGEIGVGLPIVITPSKLYLNELRPFVQAEFSYADHESFTEEGDQARAFRSGHLMNLSVPVGVKFDRCSSTHPNKYSFMGAYICDAYRTISGTQTTLLSHQETWTTDAFHLARHGVIVRGSMYASLTSNIEVYGHGRYEYRDTSRGYGLSAGSKVRF
What are the official names of this protein?
Probable outer membrane protein PmpG, Polymorphic membrane protein G.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.
Protein: SYFA_ACTSZ
Sequence: MQNLKQITEQARAALDELHDKGIEALENFRVEYFGKKGHFTQLMQGLRDVLPEERPAMGAKINEAKQTVLEILNAKKEQIEQAALNVKLEQERIDVSLPGRKVEAGGLHPVSITIGRVTKFFSELGFSVESGPEIESDYYNFDALNIPKHHPARADHDTFWFNPELLLRTQTSGVQIRTMEKKQPPIRIMAPGRVYRNDYDQTHTPMFHQIELLYVDKNANFTELKGLLHDFLRAFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPNEYSGFAVGMGVERLTMLRYNVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_SALRD
Sequence: MLDLDTVRNDPRRVKEALRAKGIGSPDLVDTLLEIDETRRSAITELQDVQSRQNELSQQIGALKREGKDEEAEAIIEKTGRMKEKINRLKEEVQEAEARQEELVLELPNIPHPSVPVGADEDDNEVEATVGEMPAFDFDPAPHWELADRHNLVDLERGAKVAGSGFPFYLGKGARLQRALLNFFLDRARERGYTEMQAPLFVNPESAKGTGQIPDKDALMYEIPRDDFYPIPTAEVPVTNFHRDEILAADDLPRRYCTYSPCWRREAGSYGSDVRGLNRLHQFDKVELVRIVPPDESYRALDALLEDAESALDALDLPYRRLLMCTGDMGFTQAKVYDLEVWSAAQERWLEVSSVSNFEAFQARRAQIRYRLEPEAKPELVHTLNGSGLAFPRIVAALLENNQQPDGSIELPEALHPYTGFARIGAEA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLB1_RAT
Sequence: MESWPGVSLVGLLLLLLLGQGPSQIHGSSGENTSQPQQVFRTLKNFSFPCKPKKLELSVLSKSVHSLRPSDIKLVAAIGNLETPPAPGSGVVNMEKPQSLESELQNVCIGIMTALSDIIRHFNPSVLMPTCSPGKGTAGHTTIAEDLWIQAKELVRHLKDNPELDFEKDWKLITVLFSNTSQCHLCSSDQQKRHLMKHMEMLSGVLDYLHREVPRAFVNLVDLSEVLTMAQQHQETGFSPAPEICKCSEEITKLSKAVMQWSYQEAWEDLLASSKFNKHETFAVVFQSFFSEVELPLERPSPQDSTTLALRIWNSMMEPVGRKDGTLNEAERKTMKCPSQESPYLFTYRNSNYQARQLKPIGKFQMKEGTKFTCPDKDPSDSIPTTVHRLRPADIKVIGAMGDSLTAGNGAGSSPGNVLDVLTQYRGLSWSVGGDETIETVTTLANILREFNPSLKGFSVGTGKENTPRASFNQAVAGAKSDGLAAQAKKLVSLMKDDKTINFQEDWKIITVFIGGNDLCGSCNNLARFSPQTFTDNIKTALDILHAEVPRAFVNMVSVIEITPLRELFNEPKVSCPRMILRSLCPCVLNLGENSAELAQLVERNRQYQEETGKLIESGRYDTRDDFTVVLQPMFENVVMPRTLEGLPDSSFFAPDCFHFNVKTHARSAIALWKNMLEPVGRKTRHQNFEIKVPIMCPNQTSPFLSTTKNSNLGHGTSMSCEEKAPSASPPTSVHTLRPADIQVVAALGDSVTAGNGISSQEGDLADVTTQYRGLSYSAGGDKFLENVTTLPNILREFNGNLTGYSVGTGDVNSASAFLNQAVPGAKAENLASQVQTLIQKMKNDTRVNFHQDWKVITVMIGASDLCDFCKDSNRYSAANFSDHLRNALDILHKEVPRALVNLVDFMNPSIIRQVFLKNPDKCPVNQTSVLCNCVLTPGEDSHELARLEAFTKSYQSSMLQLVESGRYDTREDFSVVLQPFLFNIRLPILENGNPDTSFFAPDCILLSQKFHTQLARALWANMLEPLGKKMDTLDPKELIALACPTKDKPFLRTFRNSNYTYPIKPAIENWGSDFLCTEQSPSSKVPTSVHELRPSDIKVVAAMGDFLTTATGARPSESSSLDTPWRGLSWSIGGDGTLETHTTLPNILKKFNPSILGFSTGTLENTAGLNVAEEGARAQDMPAQAQALVKKMKSTPTINIQEDWKLITLLIGNNDLCLYCEDPENYSTREYVKYIQHALDIFYEELPRVFINVVEVMELSGLLHDQGGKCAMPLAVQKNCSCLKRSQNLMAMQELKKVNGNLQSALSELSYWHRYMQREDFAVTVQPFFRNTFVPLDERGGLDLTFFSEDCFHFSVRGHAEMAIALWNNMLEPVGKKTTSNNFTYNRTKLKCPSPENPFLYTVRNSQILLDKAKENSNTLYWAVPVAAVGGLVVGILGMMLWRTVRLVQ
What is the function of this protein?
Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity) (By similarity).  Has dual phospholipase and lysophospholipase activities toward diacylphospholipids (PubMed:9442065, PubMed:9442064, PubMed:11401559).  Preferentially cleaves sn-2 ester bonds over sn-1 bonds (PubMed:9442064).  Acts as a lipase toward glycerolipid substrates (PubMed:9442065, PubMed:9442064, PubMed:11401559).  Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity (PubMed:9442065, PubMed:9442064, PubMed:11401559).  May also hydrolyze long chain retinyl esters such as retinyl palmitate (By similarity).  May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border (Probable).
What are the official names of this protein?
Phospholipase B1, membrane-associated, Phospholipase B, Lysophospholipase, Phospholipase A2, Phospholipase B/lipase, PLB/LIP, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Note=Present in the intestinal brush border membranes.
Protein: DUSA_XYLFA
Sequence: MIPVINQEKQGISGDFRLSVAPMMNWTDRYCRVFHRVLAPSARLYTEMVHAKAVIYGDRERLLGFASVEQPVALQLGGSEPALLAKAARIAVDWGYSEINLNCGCPSDRVQAGSFGARLMREPALVADCVAAMAAVVSVPVTVKCRLGVNEDDDYGRFAKFVDWVSRASSSRMIVVHARNAWLQGLSPKENREIPPLRYDWVYRLKRERPELAVVLNGGITSVEAGLDHLLMVDGVMLGRAAYQDPYILHQFDCALSNAPLLPRALLLRALRPYVEVWLEQGLTLRHIVRHLFGLFHGQPGGRVFRQVLTQGGQRSDADWSLVEQALSIIEDQETYAAVV
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U20 and U20a in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(20/20a) synthase, U20-specific dihydrouridine synthase, U20-specific Dus, tRNA-dihydrouridine synthase A.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusA subfamily.
Protein: UL11P_HCMVM
Sequence: MLFRYITFHREKVLYLTAACIFGVYISLHDACIPVVGKIGTNVTLNAVDVLPPRDQVRWSYGPGGQGYMLCIFTGTSTTTFNNTRFNFSCLSNYSLLLINVTTQYSTTYRTMTSLDHWLHQRHNHGSRWTLDTCYNLTVNENGTFPTTTTKKPTTTTRTTTTTTQRTTTTRTTTTAKKTTISTTHHKHPSPKKSTTPNSHVEHHVGFEATAAETPLQPSPQHQHLATHALWVLAVVIVIIIIIIFYFRIPQKLWLLWQHDKHGIVLIPQTDL
What is the function of this protein?
Plays a role in the modulation of host immune response by modulating T-cell function.  Interacts with host PTPRC/CD45 and thereby reduces host TCR signaling and T-cell proliferation.
What are the official names of this protein?
Protein UL11.
What is the protein family that this protein belongs to?
Belongs to the RL11 family.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass type I membrane protein. Host endoplasmic reticulum. Note=Localizes to the host cell membrane when highly glycosylated while less glycosylated forms are found on the endoplasmic reticulum.
Protein: TPMT_PSEAE
Sequence: MQADFWHARWANNQIGFHLDEINPYLMRHLSRLRLQAGEQILVPLCGKTLDLAWLAAQGLEVLGVELSEKAVSDFFEEHDLHPEIDQLDGFRRYRVAGITLLQGDFFALQAEHLAQCRAFYDRAALIALPPEMRERYAGHLQAVLPTRSLGLLVTIDYPQAEMAGPPFAVPDEEVRGYYAGGWRIEELERGDVLGVNWKFLERGVSWLDEAVYLLERG
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.