PharMolix/UniProtQA huggingface dataset:
Protein: EZRA_LISMH
Sequence: MYYMLIGFIIVVIAVIGAGYILKRKHYQRINELEEKKIKLRERPVIDELSKVKKLKLTGQTEALFESWRSSWDEIETRLFPDLEEVLLEAEMNTDRYKFRSATNAENDIEQMLVVIEKQMDQILGGLKELLISEEKNAKESRATKEKFAELRREVLTRGFKLGETLPYVEAKLNELSESLNSYDSLTDQGDHLEAREIVIVVQKEMQVIEAQMERIPSLLHETDTILPEEMNKLRAGYEEMVRKGYYLAQMELDKEISRMKNQIDKMKKNVINLDLDEAEQGVEELHNEIDLFYDTLEHEAEARHFVKENHSPTSDKLQRQNAVSDALAEQITEVKQTYHVAEDDLAVYLKTSAKLSEAKENFEQLTTLIASGEIAYSAAQDTLKEIDAALITISAEQDKFAEELRSLRKDELEARDDAERMRRAIITLDRKMERERLPGLPEEYLSLREHMGESIDTLEKRLEEKPLNMKAVSQDWRIAEEDLIHLTEKAEEMMENVRLVEHVIQYANRYRLRNKELADELVQAENHFYNDYQYKKALEIAVTALEKVETGAFKKVEKAYASKVSVDDIE
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: RL37_SOLLC
Sequence: GRCSACAYPAARLRKYNWSVKALRRKTTGTGRMRYLRNVPRRFKTNFREGTEAAPRKKGTAAAS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
60S ribosomal protein L37.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: ZN322_MOUSE
Sequence: MENHLGENHRRCTLQKRNVTRELKKGKHTMYALKRVKKIYIRVHEITQIDNQTYQCLEREQNFCENLARMCERTYTEEKPYRCDMCEKTFIQSSDLISHQRIHNYEKPYKCSKCEKSFWHHLALSGHQRTHAGKKFYTCDICGKNFGQSSDLLVHQRSHTGEKPYLCNECDKCFSRSTNLIRHRRTHTGEKPFKCLECEKAFSGKSDLISHQRTHTGERPYKCNKCEKSYRHRSAFIVHKRVHTGEKPYKCGACEKCFGQKSDLIVHQRVHTGEKPYKCLECMRSFTRSANLIRHQATHTHTFKCLEYEKSFNCSSDFIVHQRIHMEEKPHQWSMCESDFLLGMDFVAQQKMRAQTEELHYKYSVCDKTFHHSSALLQHQTVHIDDEYICNMSEKGLDLSSHASETSRVS
What is the function of this protein?
Transcriptional activator.  Important for maintenance of pluripotency in embryonic stem cells.  Binds directly to the POU5F1 distal enhancer and the NANOG proximal promoter, and enhances expression of both genes.  Can also bind to numerous other gene promoters and regulates expression of many other pluripotency factors, either directly or indirectly.  Promotes inhibition of MAPK signaling during embryonic stem cell differentiation.
What are the official names of this protein?
Zinc finger protein 322, Zinc finger protein 322A.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly found in the nucleus.
Protein: PF23A_DANRE
Sequence: MLGIMDHHQDTVRKCKSEALPPERRKRTVEDFNKFCSFVLTYAGYIPPQKEESSWSPSSSPCTHDLSELSGEGSVKDSWTDSHSDLNNIHNLVYKAETDSSSSREFSHLPSDNSLDKMTLKDSLNHVHSKAERKKVKKLDRLSLGGPRKSISEARAHKQSKAALKKIKTSIKAERHFTSSSPLNEGFEKEELTEQAIHMHEAGLKLESNQETDLSSCETDTLVTDEDIMVESGDDSWDLITCYCGKPFAGRPMIECEECSIWVHLSCAKIKKSNVPDIFYCYRCLDSRGSTVKRDH
What is the function of this protein?
Acts as a negative regulator of autophagy.
What are the official names of this protein?
PHD finger protein 23A.
What is the protein family that this protein belongs to?
Belongs to the PHF23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MTM6_METJA
Sequence: MKVIIVKIWNKINGITLINDDFLNVDLPNESIDLIVTSPPYNVGIDYNQHDDTIPYEEYLDWTKQWLKKALTLLKKDGRLCLNIPLDKNKGGIKPVYADIVKIALDVGFKYQTTIIWNEQNISRRTAWGSFMSASAPYVIAPVETIVVLYKESWKKLSKGESDITKEEFIEWTNGLWTFPGESKKELDIQHHFR
What is the function of this protein?
A beta subtype methylase that recognizes the double-stranded sequence 5'-CCGG-3', methylates C-1 on both strands, and protects the DNA from cleavage by the MjaVI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.MjaVI, M.MjaVI, N-4 cytosine-specific methyltransferase MjaVI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.
Protein: DTD_STRP7
Sequence: MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCRB_STAAC
Sequence: MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVVFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHMYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: COX2_CEPBA
Sequence: MAHSFQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIITLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYLMDEINTPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTADLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATLMSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKHFENWSTSMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HEM1_BURCJ
Sequence: MQLLTIGINHHTAPVALRERVAFPLEQIKPALVTFKNVFLGPQAPNTPEAAILSTCNRTELYCATDDRAAREGALRWLSEYHRIPVDELAPHVYALPQSEAVRHAFRVASGLDSMVLGETQILGQMKDAVRTATEAGALGTYLNQLFQRTFAVAKEVRGTTEIGTQSVSMAAAAVRLAQRIFEKVSDQRVLFIGAGEMIELCATHFAAQGPRELVVANRTAERGQRLAERFNGRAMPLADLPTRMHEFDIIVSCTASTLPIIGLGAVERAVKARRHRPIFMVDLAVPRDIEPEVGKLKDVFLYTVDDLGAIVREGNASRQAAVAQAEAIIETRVQNFMQWLDTRSVVPVIRHMHTQADALRRAEVEKAQKLLARGDDPAAVLEALSQALTNKLIHGPTSALNRVNGADRDSLIDLMRGFYQHAPRSNDQSGH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HEM3_BACSU
Sequence: MMRTIKVGSRRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKGDRIVDVTLSKVGGKGLFVKEIEQALLNEEIDMAVHSMKDMPAVLPEGLVIGCIPEREDPRDALISKNRVKLSEMKKGAVIGTSSLRRSAQLLIERPDLTIKWIRGNIDTRLQKLETEDYDAIILAAAGLSRMGWKQDVVTEFLEPERCLPAVGQGALAIECRESDEELLALFSQFTDEYTKRTVLAERAFLNAMEGGCQVPIAGYSVLNGQDEIEMTGLVASPDGKIIFKETVTGNDPEEVGKRCAALMADKGAKDLIDRVKRELDEDGK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: HEMH_THEVB
Sequence: MASQTGVLLLNLGGPDRPEDVRPFLYNLFSDPEIIRLPFRWLQKPLAWFISTSRARRSQANYAQIGGGSPLRRITEQQARALKDALEGIGIEANLYIGMRYWHPFTEEAIAQIKADQIRELVILPLYPQFSISTSGSSFRLLESLWNQDPELQKIRYTLIPSWYNHPGYVAAMADLIRQELDRCPNPDEAVIFFSAHGVPKSYVTEAGDPYQEEIEACVRLIMAALNRPNAHVLAYQSRVGPVEWLQPYTEDVILELAAQGVKTLVVVPISFVSEHIETLQEIDIEYREIAAEAGIEVFRRVPALNDHNGFISALAQLVKEALAAPPRTFAEVNQSRKRVKLYPQERWEWGMTSAAERWNGRLAMLGFLALMIELISGQGPLHMLGLL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRX1_VACCC
Sequence: MAEEFVQQRLANNKVTIFVKYTCPFCRNALDILNKFSFKRGAYEIVDIKEFKPENELRDYFEQITGGRTVPRIFFGKTSIGGYSDLLEIDNMDALGDILSSIGVLRTC
What is the function of this protein?
Displays thioltransferase and dehydroascorbate reductase activities.
What are the official names of this protein?
Glutaredoxin-1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: ALR_MYCUA
Sequence: MTTTPISLTPGVLAEAVVDLGAIAHNVRLLRERAGSAQVMAVVKADGYGHGATAVARTALAAGAVELGVASVDEALTLRADGITAPVLAWLHAPGMDFGPALAADVQIAISSIRQLDEALDAARRTGTTATVTVKIDTGLNRNGVAPALYPEMVTRLRQAVAEDAIRLRGLMTHMVHADAPEKPINDIQSQRFKQMLDHARDQGVRFEVAHLSNSSATMARPDLTLDLVRPGIAVYGLSPVPRLGDMGLVPAMTVKCAVALVKSVSAGEGVSYGHTWIAPHDTNVALLPIGYADGVFRSLGGRLEVLINGKRRPGVGRVCMDQFLVDLGPGPLDVAEGDEAILFGPGTRGEPTAQDWADLVGTIHYEVVTSPRGRITRVYREAETVER
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: GATB_STRA1
Sequence: MNFETVIGLEVHVELNTNSKIFSPSSAHFGQEQNANTNVIDWSFPGVLPVMNKGVIDAGIKAALALNMDIHQNMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWIEIELEDGTRKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEEFGTKAELKNLNSFNNVRKGLIHEEKRQAQVLRSGGQIQQETRRFDETTGETILMRVKEGSSDYRYFPEPDLPLFDISDEWIDQVRLELPEFPQERRAKYVSSFGLSSYDASQLTATKATSDFFEKAVAIGGDAKQVSNWLQGEVAQFLNSESKSIEEIGLTPENLVEMIGLIADGTISSKIAKKVFVHLAKNGGSAEEFVKKAGLVQISDPEVLIPIIHQVFADNEAAVIDFKSGKRNADKAFTGYLMKATKGQANPQVALKLLAQELAKLKEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RS15_BREBN
Sequence: MALTQERKTQLIQEFRTHENDTGSPEVQIAILTENINNLNGHLRTHKKDHHSRRGLLKMVGQRRNLLTYLREADVQRYRSVVDRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: WUHO_DROGR
Sequence: MTTIFYAEPELVIAYGRKVLFLNPNDLQIFKDIELPADLTSCGLKITAPEISEEQQSTSEGKGTDGGKVEVAILNVCYSPDRQLIALTTAGQKALLLYKSRPEHAKLLSVRALARASSAMTFAADSSSVLVTDKTGDCYQYDCVEVNALPRLLLGHLSIVYDILWTPDQKHIITSDRDDKIRVTNYPATFDIHSYCLGHKEFVSGLALLTEEHLLSVSGDKTLRLWNYLSGMELLHHDLPAPAVRLHMRELLPAKRYQAAVQFYDHIEAIGLYELEQTNNIWTVACEQLVRAEAGSWNISNFALTSDMIYVAGAVNEHLALRVYNASDGEQAKTVPAGWLDMVTGSFSDQTCVPEDLSVWFKKRYDNVSDYMERKKRRIEGQQQK
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.  Required during gametogenesis.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to the nuclei of nurse cells, follicle cells and oocytes at early stages, from germarium to stage 4 egg chambers. Also present in the nuclei of spermatocytes and in the apical cells of the testes.
Protein: DXS_FRASN
Sequence: MSLLSTIDSPQDVKRLDHEELVTLAAEIRDFLIHAVARTGGHLGPNLGAVELTLAIHRVFDSPFDRVLWDTGHQSYVHKILTGRREQFDRLRQRGGLSGYPSQAESEHDIIENSHASTALSYADGLSRAYELRGENRAVVAVVGDGALTGGMCWEALNNIAASDRQVVIVVNDNGRSYSPTIGGLADHLASLRLAPEYEQVLDVVKQVLGRTPLVGAPLFDALHGIKKGIKDVVTPQGMFEDLGLKYVGPVDGHDVVAMESALRRAKDFGGPVIVHAMTRKGFGYPAAEQDDADNFHAVGVIDPVTGKPKSASKGTTWTSIFSEEIVRIGSERPDVVTMTAAMLQPVGLKSFAKAFPDRVFDVGIAEQHAVTSAAGLAMGGLKPVVCIYATFLNRAFDQVLMDVAMHRQPVTFVLDRAGITGEDGASHNGMWDMSFLQVVPGLAIAAPRDAATLRAELDEAVSNTDGPTVVRYPKGKVAADSPAIDQVGGVDVLYRAPAAARHREVLLVSIGAMAPTCLDVAERVASQGIGITVVDPRWVKPLDPALVDLARDHDLVVTVEDNGRVGGVGACVAQLLRDADVDVPVREFGVAQRFLDHGKRDDVLAEVGLAPQDLARKVIEAVAKRQHALMGDEVGADESNQTPAGGGQA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: HFLD_YERPS
Sequence: MAKNYYDITLALAGICQSARLVQQLAHEGQCDNDALNTVLRGLLQTNPSSTLAVYGDTEQVLKMGLETLQSVLNANRQGEAAELTRYTLSLMVLERKLSASKSAMNTLGERISQLDRQLAHFDLESETMMSSLASIYVDVVSPLGPRIQVTGSPAILQSPLVQAKVRATLLAGIRSAVLWQQVGGSRLQLMFSRNRLFKQAQSILAHT
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RN2A_RANLU
Sequence: GILDSFKGVAKGVAKDLAGKLLDKLKCKITGC
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E. coli.  Weak activity against C. albicans.
What are the official names of this protein?
Ranatuerin-2La.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: KITH_CLOBK
Sequence: MYGPKDHGWIEVVAGPMYSGKTEELIRRIRRAEIAKQKVQVFKPEIDNRYSKQDVVSHAGDKIQSVPVKSSKEILEKLLDDTDVIGIDEAQFFDDFLVEIVSKIANNNRRVICAGLDMDFKGEPFGPMPKLMAIAEFVDKIQAVCMVCNNPATRTQRLINGKPAKKSDPVVLIGAQESYEARCRKCHRVPR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX5_DANRE
Sequence: MKCPNYTEDSTVLCHMEKTETDLGEVKGHKVSPRKTGALSLRSPAATNVSTPLESRSKGPHNKENYQNKRHSLDMASDDEVIFSGSGLTEDSGYLSLHNSQVDVDGLDSLERSEENCVSSQSLDVECHSGPCLPVLNFQEEACRELQRSYKKNRSYDWTVVDKVAENFGLHNVIGGKMGRQFVDILCKLMRKDMRHILARILGLLGDCDLISCTKVSRTWRKIICQDQLALQRWKKAEKTRRDSGRSMGSLSRDFTLDRVVFSCMQTVSSPPAHKAVKKPPCHMGGAQNATKSSRFQQYVEAAQSLKQHESLRRCSRCSSPARFDAVMQRAVCTRISCAFEFCTLCQSAFHDSTPCRNTVRSFSSTQKTLVAGSARSKRSIRRL
What is the function of this protein?
During embryonic development, regulates the integrity of the genome and therefore the cell cycle progression by preventing rereplication through an APC-Cdh1-dependent mechanism.
What are the official names of this protein?
F-box only protein 5, Early mitotic inhibitor 1, Harpy protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ASTE_VIBCH
Sequence: MTKSLFRQSFLFDSLDLDHPMVAQTVRTEQGVTLKLHQRGVLEVIPAQTDAATKNMVISCGIHGDETAPMELLDKWIDDIVSGFQPVAERCLFIMAHPQATVRHVRFIEQNLNRLFDDKPHTPSTELAIADNLKVLLRQFFANTDEHSRWHLDLHCAIRGSKHYSFAVSPKARHPVRSRSLMQFIEQAHIEAVMLSNAPSSTFSWYSAEHYAAQALTLELGQVARLGENLLDRLLAFDLAMRDLISRHKPEHLPRKSVMYRVSRTIVRLHDDFDFRFSDDVENFTAFMHGEVFGHDGDKPLMAKNEGEAIVFPNRKVAIGQRAALMVCKVNTRYEDDQLVYD
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: EFG_SALPB
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVGQIKTRLGANPVPLQLAIGAEEGFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMQDLANEWHQNLIESAAEASEELMEKYLGGEELTEEEIKQALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKTARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPENPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYREAIRAKVTDIEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKSGPLAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDDAPNNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INSR_XENLA
Sequence: MGQGVLRGEGHPNNNPNSKVGWKSLVGIITIFMLILCDQSDGKICYSMDIRNNISQFSMLEDCTVIEGHLQILLMFTSKPENFRGLRFPKLTTITDYLLLFRVYGLESLKDLFPNLTVIRGTRLFFNYALVIFEMVHXKEIGLYNLMNITRGSVRIEKNNELCYLSTIDWSIILDSVEDNYIELNRDNKEECGDVCPGTVKGKSKCKHTLVNGALVERCWTQDHCQKVCPSDCKGSGCLPDGQCCHPECLGSCRKPNDPSECTACRHFQNEGVCVTACPKGSYQFQGWRCIDFNTCQELNSRCQNSRDNSCPPYVIHKGECMPDCPSGYIANSTTRTCTPCAGPCPKVCTIFQNVKTIDSVTSAQELRGCTVINGSLIINLRGGNNIATELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGEVLEAGNYSFYALDNPSLRQLWDWHKHNLTIIHGKLFFHHNPRLCLSQIHQMEEVTGTKGRQDKNDIATKTNGDQASCEDNLLTFNFIKTSHDMVLLRWDAYWPPDYRDLLGFMVHYKEAPFQNVTEFDGQDACGSNSWTVVDMDAPERSADGKTQSPGCLLRSLKPWTQYAVFVKTLVSGSDEGRTYGAKSKIIYIRTNETIPSVPLDPFSVSNSTSQIILKWKPPSEPNGNVTHYLVYWQEQPEDSDLYEVDYCNKGLKLPSRTWTPPTEIDENGNENQTEHTSVNKCCPCPKTEFQIQKEQDESAFRKTFENYLHNEVFIPRPVRKRRDLFGVANGTLPDPVTAPPLFNVSSTRAPDEPEPKIYSQKVWFKESVLISGLKHFTGYRIEIHACNHELSMGCSVAAYVNARTMPEATADKVVGPITYEYVEPNIIHLKWQEPKDPNGLIVLYEVHYSRVGGIEEVITCVSQKQYNTDKGGKLRVLTPGNYSVKIRATSLAGNGSWTEQAYFQVPDHPHSNIVKIITGPIIAVFLLLIVLVYCVVQKKKDAEGPAGPLYTSSNPEYLSASEVYIPDEWEVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSLRPDAENNPGRLAPTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVADDYAVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGSLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLKDDLRPSFQDVSFYYSDENKPPETDDLEIDFENMESTPLDPSSCSLRDQSSRTNIYEEHIPYTHMNGGRKNGRILSLPRSSPS
What is the function of this protein?
Receptor tyrosine kinase which mediates actions of insulin.  May be required for forelimb regeneration.
What are the official names of this protein?
Insulin receptor, IR, XTK-1b, Xe-InsR.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RSMA_STAAR
Sequence: MLDNKDIATPSRTRALLDKYGFNFKKSLGQNFLIDVNIINNIIDASDIDAQTGVIEIGPGMGSLTEQLARHAKRVLAFEIDQRLIPVLNDTLSPYDNVTVINEDILKANIKEAVENHLQDCEKIMVVANLPYYITTPILLNLMQQDIPIDGYVVMMQKEVGERLNAEIGSKAYGSLSIVVQYYTETSKVLTVPKSVFMPPPNVDSIVVKLMQRTEPLVTVDNEEAFFKLAKAAFAQRRKTINNNYQNYFKDGKQHKEVIIQWLEQAGIDPRRRGETLSIQDFAKLYEEKKKFPQLEN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4316_PSEPW
Sequence: MLLHIPGLFDADELARIREALEQADWADGKATAGYQSAKAKHNLQLPEGHALAKEIGSALIDRLWKNPRFMSAALPHKVFPPLINCYREGGNFGFHIDNALRQPKGSPERVRTDLSSTLFLSDPDSYDGGELVIQDTYGEQQVKLAAGDLVLYPGTSLHKVNPVTRGVRYAAFFWTQSLVREDSQRALLFEMDNAIQQLTADVPEHPSLLQLTGTYHNLLRRWAEV
What are the official names of this protein?
PKHD-type hydroxylase PputW619_4316.
Protein: FGF4_CHICK
Sequence: MLSAAALLPALLLGLLWPGAVRGRPPPGRLPPGPRQRRWDAALFARSVARLPAERRDAARDGDYLLGYKRLRRLYCNVGIGFHIQVLPDGRIDGIHSENRYSLLEISPVERGVVSIFGVRSGLFVAMNSKGKLYGSTHVNDECKFKEILLPNNYNAYESRIYPGMYIALSKNGRTKKGNKVSPTMTVTHFLPRI
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.  Required for normal limb development during embryogenesis (By similarity).
What are the official names of this protein?
Fibroblast growth factor 4, FGF-4, Heparin-binding growth factor 4, HBGF-4.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_JANMA
Sequence: MAIERTLSIIKPDAVAKNVIGQIYSRFEGAGLKIVAARMTQLSRAEAEGFYAVHSARPFFKDLVDFMISGPVIIQVLEGENAIIKHRDLMGATDPKKADKGTIRADFADSIDANAVHGSDAEETAKVEIAYYFPALNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.