PharMolix/UniProtQA huggingface dataset:
Protein: METK_YERE8
Sequence: MAKHLFTSESVSEGHPDKVADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEVTTNAWVDIEEITRRTVREIGYVNSEMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETSVLMPAPITYAHRLVERQAEVRKNGTLPWLRPDAKSQITFQYDDGKIVGIDAVVLSTQHSDDISLTDLQEAVMEEIIKPVLPAEWLSKETKYHINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTGKIAEDRLVALVREFFELRPYGLIQMLDLLHPIYRKTAAYGHFGREEFPWEKTDKAALLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGP_THESM
Sequence: MIKAISIDIDGTITYPNRRLQENAVEAIRLAENLGIPVMLVTGNSACFAYAATILIGTTGPFIAEDGGVIGDKSNNRIFLGDMGDSMILWSELKKRYPNAEMSDTMKYGERRAGLVIKRTVPVEVVRGIIEELNLDLIAVDSGYAIHVKQPHVNKGEGIRNACQKLGITPEQVAHIGDGENDLDAFKVVGYRVAVAQAPEVLKREADHVTTKPYGDGGAEGIIHILKKFGYLEI
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: KATG_ALTMD
Sequence: MNMNRFRKTTLSALVALSLGATGAIANDQISKPAGAKGTGMTKAFQPKSNQFWWPDQLDLSPLRDHDNRSNPLGEDFDYAKAFSKLDLDQVKSDINELLTTSQDWWPADFGNYGPFFIRLSWHSAGTYRTLDGRGGGDGGQMRFDPLNSWPDNGNLDKARRLLWPIKQKYGESLSWGDLMILAGTVGMENMGFDTYGFAGGRTDDWEPDMVYWGPEVEMLASDREEREGKLQRPLGATHMGLIYVNPEGPKGVPDPMGSAKNIRTAFARMAMNDEETVALIAGGHTFGKMHGAHKPADCLEAEPGGAGLEEQGLGWKNNCGKGNAEDTVTSGLEGAWTQLPTKWTSLYLQNLLGFEWKQTRSPAGAIQWVPTDESLHTSVPDAHVEGKKNPPVMTTADLALKYDPEYRKIAERFLADPKEYQTAFAKAWFKLTHRDMGPKERYLGNDIPRENFIWQDPVPKADYKTISDKDVKKLKADILDSGLTVQQLVKTAWAGASSFRASDLRGGANGARIALEPQMSWEANEPETVKAVVAKLKELQEDYNSRMFSKKKVSLADLIVIGGAAAIEKAAADAGVEVSVPVVPGRTDATQEQTDVNSFSLLEPTADAFRNYYNAEASYRSPTDMLVDKADQLNLTVPEMTVLLGGLRSLGANTGGTNHGVFTDNVGTLNNDFFVTLLDMGVKWRKTDDASVYEGVNRSTGEVMYTGTPVDLVFGSNSELRAVAEVYAYDNAKTRFVEDFVDAWTKVMTLDRFDLRHDLNAKLAK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: GMHA_HELPJ
Sequence: MIDDLIQKEFLAHKEALEKSLESLQDALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTGRYKLERKGLSVISLSTDTSALTAIANDYGYEEVFARQVEALGNKEDILIGISTSGNSKNVLKAYEKAKDLGMKTLSLAGRDGGKMKPLSDIALIVPSGDTPRIQEMHILMIHILCDCIERHFARKN
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUC2D_HUMAN
Sequence: MTACARRAGGLPDPGLCGPAWWAPSLPRLPRALPRLPLLLLLLLLQPPALSAVFTVGVLGPWACDPIFSRARPDLAARLAAARLNRDPGLAGGPRFEVALLPEPCRTPGSLGAVSSALARVSGLVGPVNPAACRPAELLAEEAGIALVPWGCPWTQAEGTTAPAVTPAADALYALLRAFGWARVALVTAPQDLWVEAGRSLSTALRARGLPVASVTSMEPLDLSGAREALRKVRDGPRVTAVIMVMHSVLLGGEEQRYLLEAAEELGLTDGSLVFLPFDTIHYALSPGPEALAALANSSQLRRAHDAVLTLTRHCPSEGSVLDSLRRAQERRELPSDLNLQQVSPLFGTIYDAVFLLARGVAEARAAAGGRWVSGAAVARHIRDAQVPGFCGDLGGDEEPPFVLLDTDAAGDRLFATYMLDPARGSFLSAGTRMHFPRGGSAPGPDPSCWFDPNNICGGGLEPGLVFLGFLLVVGMGLAGAFLAHYVRHRLLHMQMVSGPNKIILTVDDITFLHPHGGTSRKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDLLAQREIKLDWMFKSSLLLDLIKGIRYLHHRGVAHGRLKSRNCIVDGRFVLKITDHGHGRLLEAQKVLPEPPRAEDQLWTAPELLRDPALERRGTLAGDVFSLAIIMQEVVCRSAPYAMLELTPEEVVQRVRSPPPLCRPLVSMDQAPVECILLMKQCWAEQPELRPSMDHTFDLFKNINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTDRLLTQMLPPSVAEALKTGTPVEPEYFEQVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGTFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNLSTVGILRALDSGYQVELRGRTELKGKGAEDTFWLVGRRGFNKPIPKPPDLQPGSSNHGISLQEIPPERRRKLEKARPGQFS
What is the function of this protein?
Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors.  Plays an essential role in phototransduction, by mediating cGMP replenishment (PubMed:21928830, PubMed:30319355, PubMed:26100624, PubMed:9600905, PubMed:15123990).  May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity).
What are the official names of this protein?
Retinal guanylyl cyclase 1, RETGC-1, CG-E, Guanylate cyclase 2D, retinal, Rod outer segment membrane guanylate cyclase, ROS-GC.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Photoreceptor outer segment membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: JAK3_MOUSE
Sequence: MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDYLAEDLCVRAAKACGILPVYHSLFALATEDFSCWFPPSHIFCIEDVDTQVLVYRLRFYFPDWFGLETCHRFGLRKDLTSAILDLHVLEHLFAQHRSDLVSGRLPVGLSMKEQGEFLSLAVLDLAQMAREQAQRPGELLKTVSYKACLPPSLRDVIQGQNFVTRRRIRRTVVLALRRVVACQADRYALMAKYILDLERLHPAATTETFRVGLPGAQEEPGLLRVAGDNGISWSSGDQELFQTFCDFPEIVDVSIKQAPRVGPAGEHRLVTVTRMDGHILEAEFPGLPEALSFVALVDGYFRLICDSRHYFCKEVAPPRLLEEEAELCHGPITLDFAIHKLKAAGSLPGTYILRRSPQDYDSFLLTACVQTPLGPDYKGCLIRQDPSGAFSLVGLSQPHRSLRELLAACWNSGLRVDGAALNLTSCCAPRPKEKSNLIVVRRGCTPAPAPGCSPSCCALTQLSFHTIPTDSLEWHENLGHGSFTKIFRGRRREVVDGETHDSEVLLKVMDSRHRNCMESFLEAASLMSQVSYPHLVLLHGVCMAGDSIMVQEFVYLGAIDMYLRKRGHLVSASWKLQVTKQLAYALNYLEDKGLPHGNVSARKVLLAREGGDGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEAQTLCLEADKWGFGATTWEVFSGGPAHITSLEPAKKLKFYEDQGQLPALKWTELAGLITQCMAYDPGRRPSFRAILRDLNGLITSDYELLSDPTPGIPSPRDELCGGAQLYACQDPAIFEERHLKYISLLGKGNFGSVELCRYDPLGDNTGPLVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLHTDRLLLFAWQICKGMEYLGARRCVHRDLAARNILVESEAHVKIADFGLAKLLPLGKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGPEREGPPLCRLLELLAEGRRLPPPPTCPTEVQELMQLCWAPSPHDRPAFGTLSPQLDALWRGRPG
What is the function of this protein?
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation.  Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development.  In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R and IL21R.  Following ligand binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins.  Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor.  Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription.  For example, upon IL2R activation by IL2, JAK1 and JAK3 molecules bind to IL2R beta (IL2RB) and gamma chain (IL2RG) subunits inducing the tyrosine phosphorylation of both receptor subunits on their cytoplasmic domain.  Then, STAT5A and STAT5B are recruited, phosphorylated and activated by JAK1 and JAK3.  Once activated, dimerized STAT5 translocates to the nucleus and promotes the transcription of specific target genes in a cytokine-specific fashion.
What are the official names of this protein?
Tyrosine-protein kinase JAK3, Janus kinase 3, JAK-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Cytoplasm.
Protein: GPR75_HUMAN
Sequence: MNSTGHLQDAPNATSLHVPHSQEGNSTSLQEGLQDLIHTATLVTCTFLLAVIFCLGSYGNFIVFLSFFDPAFRKFRTNFDFMILNLSFCDLFICGVTAPMFTFVLFFSSASSIPDAFCFTFHLTSSGFIIMSLKTVAVIALHRLRMVLGKQPNRTASFPCTVLLTLLLWATSFTLATLATLKTSKSHLCLPMSSLIAGKGKAILSLYVVDFTFCVAVVSVSYIMIAQTLRKNAQVRKCPPVITVDASRPQPFMGVPVQGGGDPIQCAMPALYRNQNYNKLQHVQTRGYTKSPNQLVTPAASRLQLVSAINLSTAKDSKAVVTCVIIVLSVLVCCLPLGISLVQVVLSSNGSFILYQFELFGFTLIFFKSGLNPFIYSRNSAGLRRKVLWCLQYIGLGFFCCKQKTRLRAMGKGNLEVNRNKSSHHETNSAYMLSPKPQKKFVDQACGPSHSKESMVSPKISAGHQHCGQSSSTPINTRIEPYYSIYNSSPSQEESSPCNLQPVNSFGFANSYIAMHYHTTNDLVQEYDSTSAKQIPVPSV
What is the function of this protein?
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES.  Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation.  Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases.  CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 75.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HCY4_CARMA
Sequence: GFGEDIAMKQHQVNSLLDILFVF
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin subunit 4.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: NS1_I01A3
Sequence: MDSNTVSSFQVDCFLWHVRKRFADRELGDAPFLDRLRRDQKSLRGRGNTLGLDIETATRAGKQIVERILEEESDEALKMPAPRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIKMDQAIMDKNIILKANFSVFFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSDEDGRPPLPPNQKRKMARTIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: SYDC_CAEEL
Sequence: MADAAEGEQPKLSKKELNKLARKAKKDEKAGEKGGNQQQAAAMDQEDASKDFYGSYGLVNSKEKKVLNFLKVKEINVSNATKDVWVRGRIHTTRSKGKNCFLVLRQGVYTVQVAMFMNEKISKQMLKFVSSISKESIVDVYATINKVDNPIESCTQKDVELLAQQVFVVSTSAPKLPLQIEDASRRAPTDEEKASEQENQLAVVNLDTRLDNRVIDLRTPTSHAIFRIQAGICNQFRNILDVRGFVEIMAPKIISAPSEGGANVFEVSYFKGSAYLAQSPQLYKQMAIAGDFEKVYTIGPVFRAEDSNTHRHMTEFVGLDLEMAFNFHYHEVMETIAEVLTQMFKGLQQNYQDEIAAVGNQYPAEPFQFCEPPLILKYPDAITLLRENGIEIGDEDDLSTPVEKFLGKLVKEKYSTDFYVLDKFPLSVRPFYTMPDAHDERYSNSYDMFMRGEEILSGAQRIHDADMLVERAKHHQVDLAKIQSYIDSFKYGCPPHAGGGIGLERVTMLFLGLHNIRLASLFPRDPKRLTP
What are the official names of this protein?
Aspartate--tRNA ligase, cytoplasmic, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AACS_RHIME
Sequence: MQAERPLWVPDREIVERSPMAEFIDWCGERFGRSFADYDAFHDWSVSERGAFWTAVWEHCKVIGESGEKALVDGDRMLDARFFPEARLNFAENLLRKTGSGDALIFRGEDKVSYRLTWDELRALVSRLQQALRAQGIGAGDRVAAMMPNMPETIALMLATASVGAIWSSCSPDFGEQGVLDRFGQIAPKLFIVCDGYWYNGKRQDVDSKVRAVAKSLGAPTVIVPYAGDSAALAPTVEGGVTLADFIAGFQAGPLVFERLPFGHPLYILFSSGTTGVPKCIVHSAGGTLLQHLKEHRFHCGLRDGERLFYFTTCGWMMWNWLASGLAVGATLCLYDGSPFCPDGNVLFDYAAAERFAVFGTSAKYIDAVRKGGFTPARTHDLSSLRLMTSTGSPLSPEGFSFVYEGIKPDVQLASISGGTDIVSCFVLGNPLKPVWRGEIQGPGLGLAVDVWNDEGKPVRGEKGELVCTRAFPSMPVMFWNDPDGAKYRAAYFDRFDNVWCHGDFAEWTPHGGIVIHGRSDATLNPGGVRIGTAEIYNQVEQMDEVAEALCIGQDWEDDVRVVLFVRLARGVELTEALTREIKNRIRSGASPRHVPAKIIAVADIPRTKSGKIVELAVRDVVHGRPVKNKEALANPEALDLFAGLEELKS
What is the function of this protein?
Catalyzes the conversion of acetoacetate into acetoacetyl-CoA.  Is involved in poly-3-hydroxybutyrate (PHB) degradation, which allows growth of R. meliloti on PHB cycle intermediates.
What are the official names of this protein?
Acetoacetyl-coenzyme A synthetase, Acetoacetyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RPOC_CLOBL
Sequence: MFELNNFDALQIGLASPEKIREWSRGEVKKPETINYRTLKPERDGLFCERIFGPMKDWECHCGKYKRIRYKGIVCDRCGVEVTKAKVRRERMGHIELAAPVSHIWYFKGIPSRMGLILDMSPRALEKVLYFASYVVLDPKETPLLKKQLLNEKEYRESIDKYGDDSFVAAMGAEAVKTLLDEIDLEQSSIELKEELKTSTGQKKIRIIRRLEVVESFRKSGNRPDWMVIDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKKLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKMYQCGLPKEMALELFKPFVMKKLVQNGLAHNIKSAKRMVERVQPQVWDVLEEVISDHPVLLNRAPTLHRLGIQAFQPVLVEGRAIKLHPLVCTAYNADFDGDQMAVHVPLSVEAQAEARFLMLAAHNILKPSDGKPVSVPTQDMVLGSYYLTMDKDGVKGEGKVFSCPEEVLMAYQCKAVDIHAKIKVRLKKVIDGETIEGIIETTPGKIIFNESIPQDLGYIDRTIPENKLKLEVDFLVSKKTLGGIITKCYMKHGATKTSIMLDKIKAKGYHYSTIGAITISTSDMVVPESKRELLENTEKQVEKIQKMYRRGFISEEERYEKVIDLWTKTTEDVANALMESLDSFNPIYMMADSGARGSKSQIKQLAGMRGLMANPSGKILELPIKASFREGLDVLEYFISTHGARKGNADTALKTADSGYLTRRLVDVSQDVIVRQEDCGTEEGYEVSEIKEGNEVIEPLVERLSGRYPSEDIIHPTTGEVIVKRNTYMDEDIAQKVSDAGIKKVKIRSVFTCKSKHGVCARCYGMNMGTSQKIHIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGADITQGLPRVEELFEARKPKGLAIVSEVSGTVKMEETKKKRTIIVVTDDGEEVSYDIPFGSRIKVKNGDIISAGDEITEGSINPHDILRIKGVDGVKNYLLSEVQKVYRLQGVDINDKHLEVVIRQMTRKIKIEDSGDTELLPGTMIDVFDFEEANREILEKGGEPAVGRIALLGITKAALATDSFLSAASFQETTRVLTDAAIKGKIDPLLGLKENVIIGKLIPAGTGMTRYRSIQINTDDENIEEDSMDSMEV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RPOC1_CUSRE
Sequence: MNKNFSSMIDRYKHQQLRIGLVSPQQISAWATKILPNGEIVGEVKKPYTFLYKTNKPEKDGLFCERIFGPIKSGICACGNYRVIGDEKEEPKFCEQCGVEFVDSRIRRYRMGCIKLACPVTHVWYLKRLPSYIANILDKPIKELEGLVYCDFYFARPITKKPTFLRLRGLLKYEIQSWKSSIPLFFTTQGFDTFRNREISTGAGAIREQLADLDLKISLENSLLEWKYLGEEERIGNEWEDRKAGRRKGFLVRRMELVKHFIRTNIEPEWMVLSLLPVLPPELRPIIQIDGGKLMSSDINELYRRVIYRNNTLTDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDIIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPRKIAIELFQPFVIRDLIRQHLASNIGVAKSKIREKEPIIWEILQEVMRGHPVLLNRAPTLHRLGIQAFQPVLVEGHVLCLHPLVCKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPAIGDPISVPTQDMLIGLYVLTSDNRRDICTNRYTKCNIQTLQTKSSDSSNSKSKNWYKNRPFFCNSYDAIGAYRQKQINLESPLWLRWRLDRRVITSSETPIEVHYESRGTFSEIYGHFLIVRSLKKKILFIYLRTTVGHISLYREIEEAIQGFSRAWSSDT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: GAJU_HUMAN
Sequence: LAAGKVEDSD
What are the official names of this protein?
Gastric juice peptide 1.
Protein: RL30_FLAJ1
Sequence: MAKLLVKQVRSKINCPLSQKRGLEALGLRKLGQVVEHESNPAILGMINKVKHLVSVEEAK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TICN3_PONAB
Sequence: MLKVSAVLCVCAAAWCSQSLAAAAAVAAAVGRSDGGNFLDDKQWLTTISQYDKEVGQWNKFRDEVEDDDFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDYQTAVCISHRRLTHRMKEAGVDHRQWRGPILSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHCPCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDEIEDDDEDEGDDDDGGDDHDGYI
What is the function of this protein?
May participate in diverse steps of neurogenesis.  Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP.  May interfere with tumor invasion (By similarity).
What are the official names of this protein?
Testican-3, SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CYB_MICSO
Sequence: MTIIRKKHPLIKIINHSFIDLPAPSNISSWWNFGSLLGLCLIIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGIYYGSYNMIETWNMGIVLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDFLGVLILLMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSIVILAFMPLLHTSKQRALTFRPITQTMYWILVADLLILTWIGGQPVEYPFIIIGQTASIAYFTIIVILMPMAGMFENNILDLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EI2BB_RAT
Sequence: MPGAAAKGSELSERIESFVETLKRGGGRRTSEDMARETLGLLRRLITDHHWNNAGDLMDLIRREGRRMTAAHPPETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLSEDFSFHYAPLKSNIIEAINELLVELEGTTENIAAQALEHIHSNEVIMTIGFSRTVEAFLREAAQKRKFHVIAAECAPFCQGHEMAVNLSEAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGSLRAVAGTHTLALAAKHHSTPLIVCAPMFKLSPQFPSEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPDLITLFISNIGGNAPSYVYRLMSELYHPDDHVL
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit beta, eIF-2B GDP-GTP exchange factor subunit beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: PEPT_STRA1
Sequence: MSYEKLLERFLTYVKINTRSNPNSTQTPTTQSQVDFALTVLKPEMEAIGLKDVHYLPSNGYLVGTLPATSDRLRHKIGFISHMDTADFNAENITPQIVDYKGGDIELGDSGYILSPKDFPNLNNYHGQTLITTDGKTLLGADDKSGIAEIMTAMEYLASHPEIEHCEIRVGFGPDEEIGIGADKFDVKDFDVDFAYTVDGGPLGELQYETFSAAGLELTFEGRNVHPGTAKNQMINALQLAMDFHSQLPENERPEQTDDYQGFYHLYDLSGTVDQAKSSYIIRDFEEVDFLKRKQLAQDIADNMNEALQSERVKVKLYDQYYNMKKVIEKDMTPINIAKEVMEELDIKPIIEPIRGGTDGSKISFMGIPTPNLFAGGENMHGRFEFVSLQTMEKAVDVILGIVAKD
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAAS1_HUMAN
Sequence: MALSMSLSSDILSGAPTAGRGGGCSAALSPRGRGSKGLGTRAPGPRGDGQQPPLGTGGDEDPGAGSASAGGSRLAAAAAAEAAAPGDRSLCWAPRGRLLASSPAGEAGSWGRARRGGPRPGAPCKGLAGPPLRPGLARS
What are the official names of this protein?
Putative uncharacterized protein encoded by MAPKAPK5-AS1, MAPKAPK5 antisense RNA 1, MAPKAPK5 antisense gene protein 1.
Protein: LATA_LATPL
Sequence: EGEDLTLEEKAEICSELELQQKYVDIASNIIGDLSSLPMVGKIVGTIAAAAMTVTHVASGRLDIEQTLLGCSDLPFDQIKEILEKRFNEIDRKLESHSAALEEITKLVEKSISAVEKTRKQMNKRFDEVMKSIQDAKVSPIVSKINNFARYFDTEKERIRGLKLNDYILKLEEPNGILLHFKESRTPKDDSLQAPLFSIIQERYAVPKSIDDELAFKVLXALLYGTQTYVSVMFFLLEQYSFLANHYYEKGDLEKYDEYFNSLNNVFLDFKSSLVGTGTSNNEGLLDRVLQVLMIVKNSEFLKLGKNGVDEMLNSKINLFNKIKEEIEGKQRMTLSETPENFAQISFDKDITTPIGDWRDGREVRYAVQYASETLFSKIGHWSDPVNVRERACPTLRMPVDQTRRNVLVFRKFDNSKPQLVGEITPYLSNFIDIDRDLYNAASNPDSAVGFKEFTKLNYDGANIRATFDQGRTVFHAAAKSGNDKIMFGLTFLAKSTELNQPDKKGYTPIHVAADSGNAGIVNLLIQRGVSINSKTFHFLQTPLHLAAQRGFVTTFQRLMESPEININERDKDGFTPLHYAVRGGERILEAFMNQIDIDINAKSDKGLTPFHLAIIKNDWPVASTLLRSKKVDINAVDENNMTALHYAAILGYLEIAKQLINLKEINANIVSSPGLLSALHYAILYKHDDVASFLLRSSNVNVNLKALGGITPLHLAVIQGRKHILSLMFXIGVNIEQQTDEKYTPLHLAAMSKYPELIQIFLNQGSNFEAKTNSGATPLHLATFKGKSQAALILLNNEVNWRDTDENGQMPIHGAAMTGLLDVAQAIISLDATVLDIEDKNSDTPLNLAAQNFHIDAVKYFIDQGADINTRNKKGHAPLLAFSKKGNLDMVKYLFDKNANVYIADNDGMNFFYYAVRNGHLNIVKYAMSEKDKFEWSNIDNNRRDECPKEECAISHFAVCDAVQFDKIEIVKYFVGTLGNFGICGPLHQAARYGHLHIVKYLVEEEFLSVDGSKTDTPLCYASENGHLAVVQYLVSNGAKVNHDCDNGMTAIDKAITKNHLQVVQFLAANGVDFRRKNSRGATPFLTAVAENAFDIAEYLIREKRQDININEQNVDKDTALHLAVYYKNLQMIKLLVKYGIDVTIRNAYDKTALDIATDAKFSIIVEYLKTKSGKFRREYKSSYGEPSLLQTNKISSFIDGKNIEHDHLQFINADNESSQLFSDTVSNIDVIGTLLLVDVLIRYFSKQGYISKESDSASDGITQAAALSITEKFEDVLNSLHNESVKEQVDLAEVHGRVYAALKSGRNSRIHQILCSSLKSISTLKPEDMEELVSVIMNSQSSVSLPEVTDSANEAYGEA
What is the function of this protein?
Presynaptic neurotoxin that causes massive release of neurotransmitters from vertebrate (but not invertebrate) nerve terminals and endocrine cells via a complex mechanism involving activation of receptor(s) and toxin insertion into the plasma membrane with subsequent pore formation.  Binds to neurexin-1-alpha (NRXN1) in a calcium dependent manner, adhesion G protein-coupled receptor L1 (ADGRL1, also termed latrophilin-1 and calcium-independent receptor of latrotoxin (CIRL)), and receptor-type tyrosine-protein phosphatase S (PTPRS), also termed PTP sigma.  NRXN1 and PTPRS are suggested to provide a platform for binding and subsequent pore formation events.  In contrast, binding to ADGRL1 does not involve oligomerization and channel formation, but direct downstream stimulation of the synaptic fusion machinery.
What are the official names of this protein?
Alpha-latrotoxin-Lp1a, Alpha-LTX-Lp1a, Alpha-latrotoxin, Alpha-LTX.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 01 (latrotoxin) family. 03 (alpha-latrotoxin) subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: MTGA_BURL3
Sequence: MVAVSGTQHTRTVSPTRWIVYAGSVFAGAWLATQLFYLAQIALWSFVNPGSTAFMRTDAWWLSRDKPPAQIQHQWVPYDQISRNLKRALIASEDSTFATNNGYDVDAILQAWEKNKARGRIVAGGSTITQQLARNLFLSREKSYIRKGQELIITWMLETVLDKERIFEIYLNSVEWGRGVYGAEAAARYYYRIPASRLGAWQSARLAVMLPKPRWFDAHRGSAYQAQRAAVIARRMGAAELPQSE
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.