PharMolix/UniProtQA huggingface dataset:
Protein: FKS1_CRYNH
Sequence: MSYPNPPPPPKGSASFSSSSSDPFNQTNQLPYDSQFPPQHAFAHPSAPNPGAGGAGVAPPGQGGQYAPYYDNEPEMGGRWEGGGMGRETWASESGWSQNEPNYPPSDYHGGPGYLPSRASTPTFEGSNAGHRPRDPYPAWTVDANIPLSKEEIEDVLIDLANKFGFQKDSSRNVYDFLMIQLDSRASRMSPNQALLTLHADYIGGEHANYRKWYFAAQLDLDDAIGAVQNPGLNRVRSVARRGGKTKNPLATAQEKSLESATSRWRTAMNNMSQYDRLRQVALYLLCWGEAAQVRFMPECLCFIFKCADDYYRSPECQNRQEAVPEGLYLRAVIKPLYRFLRDQGYEVVDGKFLRRERDHDKVIGYDDVNQLFWYPEGISRITLNDNTRLVDIPPAQRFMKFDRIDWNKVFFKTYLEKRSFFHLLVNFNRIWVLHISVFWFFTAYNAPSIYAPSGSTTATTPMAWSMTGLGGFVATLIMIAATLAEFSYIPTTWNNTSHLTRRLIFLLIILAITGGPSIYIAFFNQTGHVALILGIVQFFCSVVATIAFATLPSGRMFGDRVAGKSRKYLANQTFTASYPALGFYPRVASFLLWFLVFGCKFTESYFFLTLSFRDPMKVMNGMKVQNCHDKYFGNGLCTNQPAFALAVMFVMDLTLFFLDTFLWYVIWNTVFSIARSFAIGMSIWTPWKDIFARLPKRIYAKILATDDMEVKYKPKVLVSQVWNAVIISMYREHLLSIEHVQKLLYHQIQSDQPGKRTLRAPAFFISQSEKGSKAEFFPKGSEAERRICFFAQSLTTSIPAPIPVDAMPTFTVLVPHYSEKILLSLREIIREEDQNTRVTLLEYLKQLHPVEWDNFVRDTKILAEESDAFNGGNPFASDEKEEAKKADDIPFYTIGFKSAAPEYTLRTRIWASLRAQTLYRTVSGFMNYSKAIKLLYRVENPEVVQLFGGNTDQLERELERMARRKFKFVVSMQRYSKFNKEEHENAEFLLRAYPDLQIAYLDEEPPRKDGGESRIFSALIDGHSEIMPNGRRRPKFRIELPGNPILGDGKSDNQNHAIVFYRGEYLQLIDANQDNYLEECLKIRNVLGEFEEFKVSTQSPYAAQGHADFAKFPVAILGAREYIFSENIGILGDIAAGKEQTFGTLAARSLSYIGGKLHYGHPDFLNAIYMNTRGGVSKAQKGLHLNEDIFAGMLAFGRGGRIKHSEYYQCGKGRDLGFGTILNFQTKIGTGMGEQMLSREYYYLGTQLPIDRFLTFYYGHPGFHINNILVMMSVQVFMLALVFLGTLNKQLTVCRYSSGGDILPGQSGCYNLVPVFKWIKRCIISIFIVFWIAFVPLFVQELTERGTGRAILRLCKHFLSLSPVFEVFSTQIYMHSILNDLTFGGARYIATGRGFATTRISFSILYSRFAGPSIYLGMRTLVLLLFITLTVWVPHLIYFWITVVGLCVAPFLFNPHQFAIADFIIDYREFLRWMSRGNSRTHANSWVGYCRLSRTRVTGFKRKRLGLPSEKLSSDVPRAPWKAILIGEIIGPICLAILFVICYLFIKSFAVDGQIQPGLVRIAIIALGPIVWNMALLITLFLISVFLGPCLNSYTHQFGATMAALAHFGAVAGMLVFFELLWFLELWNTSHAVLGIIAVISVQRCIFKFLIAVFLSREFKHDETNRAWWTGVWFNRGLGSHALSQPAREFVVKTIEMGLYSADFIACHLLLALLTIPMFIPYFDRVHATMLFWLAPNQQIRPPIYSFRQRSQRRKIVFKYGLLYLIIQGIFIALIVVPIIFKDVAGLTPKSVPFNGII
What is the function of this protein?
Catalytic subunit of the 1,3-beta-glucan synthase (GS) complex (PubMed:15980360).  Synthesizes 1,3-beta-glucan, a major structural component of the yeast cell wall (PubMed:15980360).  Involved in cell wall synthesis, maintenance and remodeling (By similarity).
What are the official names of this protein?
1,3-beta-glucan synthase component FKS1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 48 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YFCZ_ECOL6
Sequence: MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTLAALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR
What are the official names of this protein?
UPF0381 protein YfcZ.
What is the protein family that this protein belongs to?
Belongs to the UPF0381 family.
Protein: FLIW_THEP3
Sequence: MQINTKNFGIIEYNPDDVIYFEEGIPGFEDLHNFLIITDNREDMPFKWLQAIDNTDIAFVVIDPRVFKPNYTFEIDEELIQALQIEDINHLLIYVIVVIPDEIEKMTANLKAPIIINAKNNKGKQAILDNDEYLIKHPILEELKNAYSNA
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y032_RICPR
Sequence: MCDKIFHNLSGKTLVATPYVITKGIYHKSLIYMLSHTEEGAIGLIFNRLVNHVDLKSFFKIKEDKITSQVMVPIYLGGPIEHEKGFFLHSRDYNKNLLLDFHNDLAVSSNLEISEDIAFGKGPKNSLFIVGYTAWKPGQLEEELEKNLWLVMDCSKEFIFAENPENKWHNALKHLGIDEIYFSSQIGNA
What are the official names of this protein?
UPF0301 protein RP032.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: QUEF_SULDN
Sequence: MKYGEKIVSEFDVEKDLEIWPNEHKRDYLIKMTLPEFSCLCPRSGYPDYATIYLEYTPNERVVELKAIKLYINSFRDRHISHENSANEIYTVLERKLKPKYMKIVADYNPRGNVHTVIEIDSSKL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_PROMH
Sequence: MSKIKTRFAPSPTGYLHVGGARTALYSWLFSRHNKGEFVLRIEDTDLERSTQPAIDAIMDGMNWLNLNWDEGPYYQTKRFDRYNQVIDQMLAAGTAYRCYCSKERLEKLREDQMAKGEKPRYDGCCRHGDHNHTPDEPHVVRFLNPQEGSVIFNDKIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVIDDWDMEITHVIRGEDHINNTPRQINILKALGAPVPEYAHVSMILGDDGKKLSKRYNAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFSIDEMIKDFTLEAISKSASAFNTDKLLWLNHHYINTLPAEQVAVHLDWHIKQQNIDTSNGPSLVELIKLLGERCKTLKEMAESCHYFYVDFDSFEETAAKKHLRPVARQPLEVVRDKLSAITDWTAENVHKAIQETAEELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKARSIARINKALDFITDRENQA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFS_PECCP
Sequence: MSYPIERVRADFPLLASEVNGQPLAYLDSAASAQKPQSVIEREAEFYRHEYAAVHRGIHTLSAQATSAMEAVREQVAAFINAASVEEIVFVRGTTEAINLVANSYGRTFIQPGDNLIITEMEHHANIVPWQMLAEARGVEVRVLPLAEDGSLDVAQLPGLLDERTRLLAVTQISNVLGALNPVKTMIAQAKAVGAVTLVDGAQSIMHQTVDVQDLDCDFFVFSGHKIYGPSGIGVLYGKRDLLQAMPPWEGGGAMIRQVSLRTGTTYADSPWRFEAGSPNTGGIMGLGAALDYVTALGREEIQRYESSLMKYALEALKQVPDLTLYGPAERHGVIAFNLGQHHAYDVGSFLDRYGIAIRTGHHCAMPLMEHYGVPSMCRASLAVYTTREEIDRLVAGLQRIHRLLGS
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_LEPCM
Sequence: MXXXXGYLEFDGARQQSFLYPLFFREYIYVLAYDHGLNRLNRNRSIFLENADYDKKYSSLIVKRLILRMYEQNRLIIPTKDLNQNNFLGHTSLFYYQMISVLFAVIVEIPFSLRLGSSFEGKQFKKSYNLQSIHSIFPFLEDKLSHFNYVLDVLIPYPIHLEILVQTLRYRVKDASSLHFFRFCLYEYCNWKNFYIKKKAILNPRFLLFLYNSHICEYESIFFFLRKRSSHLRSTSYEVLFERILFYVKIQHFLKVFVNNFPAILGLLKDPFIHYVRYHGRCILATKDTPLLMNKWKYYFVNLWQCYFSVWFQSQKVNINQLSKDNLEFLGYLSSLRLNPLVVRSQMLENSFLLDNVRIKLDTKIPISSIIRSLAKDKFCTVLGHPISKATWTDSSDSDILNRFVRICRNISHYYSGSSKKKNLYRIKYILRLCCVKTLARKHKSTVRAFLKRLGSGLLEEFLTGEDQILSLIFPRSYYAYKKLYRVRIWYLDILYLNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YCX1_MARPO
Sequence: MNPFFYFVQLFFYYPFFIIFLYIYLVFFIPKTNNINFSNIFPLFSKWIKK
What are the official names of this protein?
Uncharacterized 6.4 kDa protein in atpA-psbA intergenic region, ORF50.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Single-pass membrane protein.
Protein: MURC_GEOSW
Sequence: MTVYHFVGIKGTGMSALAQVLHDMNYTVQGSDVEKRFFTQKALEERGIPILPFNKENIKPGYTVIAGNAFPETHEEIQAAHELGVPVIRYHRFLGEFLQKFTSIAVTGSHGKTSTTGLLAHVMQGVHPTSYLIGDGTGKGIEGSKYFVFEACEYRRHFLSYFPDYAIMTNIDFDHPDYFANIDDVFSAFQEMALQVKKGIIACGDDEYLQKIQAKVPVLFYGFGDDNDFQARNVVKTTEGTAFDVFVRNTFFASFEIPHFGDHNVLNALAVIALCHYEEMDVRIIQERLKTFQGVKRRFSEKVLGNQILIDDYAHHPREIIATIDAARQKYPGREIVAIFQPHTYTRTQTFLREFAESLQQADQVYLCDIFGSAREHHGKLSIHDLQAQIPNSRLIQEDNTSILKQHENAVLIFMGAGDIQKFQEAYERTVHS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZFY16_MOUSE
Sequence: MDSYFKAAVSGLDKLLDDFEQNPDKQDYLPDAYAFNQCSVSSESASPQLALLSKDQRCISTCASSEACCEDANETFLEGKIHEGLTSRPNEKNVAGLDLLSSVDASTSDEIQPSCMRRCSKPVCDLISDMGNLVHATNSEEDIKQLLPDDPKSSADTLITLDSSSVSEALTVSSVDCGSNAVREEQNNINAGIKNRDISIKELGVKVDMALFDSCKYNRTENLKDKIISNELETVDFDMPSVLMEQSSEMSNTKDNPQYKRLPCELLKDDGCLAEEKVAVAVNNTECLEEGGGSNTIAMPCKLPENEGISPSDPASKDENFKLPDFPLQENRTSVFMKQTVKEDSRNLDLKDNNDIVHVSGDDVPPSLSCLSLSGSLCGSLIHNNEHSDILPPNESEGQNNDAVTIHEEIQKSDVLDGETDLSKKETCRSIFLQPVNEKKGEGKVEVEEMVISGESLESPEDASSAAAAGSPVALSAASVPEAPGPCEGLTFPSSDMDGQELDYFNIDESMRSGILISDAELDAFLKEQCLSNSNTMSAGENVNDSQLQMNQITMKGLHDENAGDIYFNAEAGAAGENGGVGNCETSDKENTENNGLSIGEKGAIPTERELSACQPDIRDELPVPSIKTQAVGGARPKQLLSLPPGTRSSKELNKPDVVDVPESEPCTANATAVSTCSADHIPDSQVSFNSNYIDIESNFEDGSSFVTANKDSLPENKRKESLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVICYETINKAQAFERMMSPGGSCLKSNHSNECATDQPLQETQTSSTPSPTTLPISALKQPNVEGPCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSDDFSPVLPDVPTMINKVDRTHSPTVEKPNNGLGDIIRSEISQSPTCHTAPVERLPGNTGTEGLPMPGPFTLEDDVFVDSEEPSTPTVVPANSGLPVASISDYRLLCSVAKCVCNNISLLPDDDIGLPPLLATSGEDGSVPVVQERPSHEQIILLLEGEGFPPATFVLNANLLVNVKLVLYSSEKYWYFSTNGLHGLGQAEIIVLLQCLPNEDTVPKDIFRLFITIYKDALKGKYIENLDNLTFTESFLNSKDHGGFLFITPTFQNLDGLPVPRSPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYKAYPAPLTSVRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVMKVIHSSNEHVISIGASFSTEADSHLVCVQSDGVYQTQANSATGQPRKVTGASFVVFNGALKTSSGFLAKSSIVEDGLMVQITPETMEGLRLALREQKDFRIQCGKVDAVDLREYVDICWVDSEERKNKGVISSVDGMSVEGFPSEKIKLETDFETEEKTVKCTEVFYFLKDQDISILSSSYQFAKEIAVACSAALCPHLRTLKSNRMNKIGLRVSIDTDMVEFQAGCEGQLLPQHYLNDLDSALIPVIHGGTSNSSLPLEIELAFFILENLSE
What is the function of this protein?
May be involved in regulating membrane trafficking in the endosomal pathway.  Overexpression induces endosome aggregation.  Required to target TOM1 to endosomes (By similarity).
What are the official names of this protein?
Zinc finger FYVE domain-containing protein 16, Endofin, Endosomal-associated FYVE domain protein.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome membrane; Peripheral membrane protein. Note=Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P) (By similarity).
Protein: CH10_ACIET
Sequence: MNLRPLHDRVIVKRIESETTTASGIVIPDNAAEKPDQGEVLAVGPGKKNDKGELIALNVKVGDRVLFGKYSGQTVKVNGDELLVMKEDDLFAVVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_YERPB
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTTNIRNVLKHLEDDTLAIVRHWDHIELRTKDGNLGPEICDALTRIPGIHHILEVEDRSYSDMHNIFEQTLEAYRETLVGKTFCVRVKRRGKHEFSSGDVERYVGGGLNQHIESAKVNLTRPQVTVNLEVDQDKLILVKARHEGLGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGSAHEIGVKQVAHYLWNRFGSSHRVRFIAIDFEPVVGEILEKVEDGQMGVVLKRMMVRAASQVAERYGVQALVTGEALGQVSSQTLTNLRLIDNASDTLILRPLISHDKEHIINLARQIGTEDFAKTMPEYCGVISKSPTVKAVKAKIEEEESHFDFSILDRVVSEAKNVDIREIAQQSREQVVEVETVAELADTDVLLDIRAPDEQEEKPLKLDQVEVRSLPFYKLSSQFADLDQSKTYLLYCDRGVMSRLQALYLREQGYTNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMS1_YEAST
Sequence: MLGLRTHGLDRYEHYIRRPSDFGKLELQDWLNHKSFRVSPNLLIDSSTTREWNEPELFYQNTEDETWVRPCVGPKLEPSMMMLRYHDSNIGQMPQFCYPISSPINFKPVLKYILQERSELSDGFPQKYNTLIGSLFDIDKNPETLDDSDIEALDDIEMSSDSGNVKEPKIELQALEEIQQKHFSLIVSNNGIFQTGSTSITYIQSGISGSIAIKPNNVAILILLTQPSGHLLSILPLDDGKETYLLQYWNLGQKGQWNIIKHQNEKQFVLIHKELGICKFFEFHLPFTFQLVNNLTLTDSVIMNGSFFPTNYTDLDPYFIIFITAIRYERIVYFVIEWNNNEIKKKEVYQLTVFDGEKTNMTIPIGLNACLVETPLKFSLVSANQIMSGETEFHSFQLKALKGIKSFFPAPLLLLKLQELHPHTFKKFQYCTIISSSTGNICFCVTERSTIVNGNLKFYELTRFKGLKSISPLPSNPINLDSRSSSYVLVVISFSRTLELTLSLEDLRCLDKKDVIKPLKNITFKHTIDSSTEENSQILAFTSSKFYNTHTGSNINDTRNSQVWLTSPNAITQPCIDYKLRKTHQLIHLKQFQIFRHLRIWKCKNLDIALLQRLGINQSNTESSLIFATDAVSNNRIFLLDLTMTTTIDNDDPVQGLINIEDLLCDTENETILLNFTKNNLIQVTRDTIYIDPIGGDKELRKISPGWEFENVTYNDGILIVWNAGLGCVSYIENIDAVDESGALVSNLSSSKGMSKFFKQLGTVTSVNFQIKESTDDPTKYDIWILLPDCVIRTPFSDWISDSLDFSDVYILSVQQALINGPYFCSLDYESYFEVHTLQNNCFKKGSRCTSRVNFQGKDIKFRSFGVNQCLAFSAFEIFVINLTPIHDSRELDFYKLKLPHLGNNNSILEVCPDIENNQLFILYSDGLRILELSYLTSNNGNFLLKSTRSKNKKFLYLDKINRMLVLNQDLREWECIRLSDGKAVGLDSQLLKDDSEEILEIKELPIATEDNPLEKKTVLLISFTSSLKLVLLTAAKNKISNQIIDSYKLDNSRLLNHLVITPRGEIFFLDYKVMGTDNEMSFNKLKVTKHCIDQEERNNTTLRLTLETRFTFKSWSTVKTFTVVGDNIIATTNMGEKLYLIKDFSSSSDESRRVYPLEMYPDSKVQKIIPLNECCFVVAAYCGNRNDLDSRLIFYSLPTIKVGLNNETGSLPDEYGNGRVDDIFEVDFPEGFQFGTMALYDVLHGERHVNRYSEGIRSENDEAEVALRQRRNLLLFWRNHSSTPKPSLRRAATIVYEDHVSSRYFEDISSILGSTAMRTKRLSPYNAVALDKPIQDISYDPAVQTLYVLMADQTIHKFGKDRLPCQDEYEPRWNSGYLVSRRSIVKSDLICEVGLWNLSDNCKNTV
What is the function of this protein?
Component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes (CRLs), which mediate the ubiquitination of target proteins.  The CRL associates with CDC34 as the E2 ubiquitin-conjugating enzyme.  The functional specificity of the CRL depends on the type of the associated substrate receptor protein.  RTT101(MMS1-MMS22) promotes fork progression through damaged DNA or natural pause sites by stabilizing replication proteins like the replication fork-pausing complex (FPC) and leading-strand polymerase at stalled replication forks.  RTT101(MMS1-MMS22) ubiquitinates the acetylated histones H3K56ac-H4 at lysine residues H3K121, H3K122 and H3K125.  Ubiquitination is required for efficient histone deposition during replication-coupled nucleosome assembly, probably by facilitating the transfer of H3-H4 from ASF1 to other chaperones involved in histone deposition.  RTT101(MMS1-CRT10) may regulate nucleotide synthesis through transcriptional regulation of ribonucleotide reductase.  RTT101(MMS1) is also involved in the non-functional rRNA decay (NRD) of 25S rRNA through the selective, ubiquitination-dependent degradation of nonfunctional ribosomal particles.  Involved in the regulation of TY1 transposition.
What are the official names of this protein?
E3 ubiquitin-protein ligase linker protein MMS1, Methyl methanesulfonate-sensitivity protein 1, Regulator of Ty1 transposition protein 108, Synthetically lethal with MCM10 protein 6.
What are the subcellular locations of this protein?
Nucleus. Note=Enriched on chromatin at sites where replication forks have stalled.
Protein: PEPT_PASMU
Sequence: MLNQQQTYKLLERFLHYTTYDTQSKSGAKISPSSAGQLKLAKHLQQELFALGLQDIDISKHSVVTAFLPSNVNPHSPTIGFIAHLDTATQCSGKNVQAEVIENYRGGDIALGVGEEFISPAHYQFLHQLIGKTLVVADGNTLLGADNKAGIAEIMTALAVLKEENLPHCNIRVAFTPDEEIGLGMQFFPVEKFPCDWAYTIDGGEVGELEYENFNAATAIVTIEGVNMHTGSAKDKMINALTLACEFQQGFPAEETPEQTEGKQGFYHLSHFTGHVEKVELQYLIRDFDRDGFEQRKIFIQQLVDRFNQQKRLKKPITLEIKDSYKNMNEVVKTVPQSVELADSAMRECGIEPIHKAIRGGTDGAWLAEQGLACPNVFTGGYNFHSKHELITLEGMQSAVNVITTIVRLATS
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_SHEPA
Sequence: MSNKIISLGSIEIANDKPFVLFGGMNVLESRDLAMQIAETYAEVTQKLGIPYVFKASFDKANRSSVNSYRGPGMEEGLKIFEEIKSTFNLPLITDVHEVHQCAPVAEVVDVIQLPAFLARQTDLVVAMAKTGAIINVKKPQFLAPHEMRHIITKFNEAGNDEIMLCERGSSFGYNNLVVDMLGMDEMKQTGYPVIFDATHALQRPGGRSDSAGGRRAQATELARSGMALGLAGLFIEAHPDPDNAKCDGPCALPLHQLENYLTQMKAIDDLVKSFEPIDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCRB_GEOTN
Sequence: MEEIRAWRHVFKLDPNKPIDDERLERLCESGTDAVIVGGTDGVTLDGVLDLLARIRRFSVPCALEVTDIEALTPGFDAYLIPMVLNSCRVDWVIGRHHEAVKQYGDVMNWDEIFAEGYCILNGECKAAKLTEANTALDDDDVVAYARLAEHLYKLPIFYLEYSGTYGNPSLVEKVKRALSRTQLVYGGGIMTPEQAAEMARYADTVVVGNAVYDSFESALATVEAVKRIDGENEISGVK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: MSCL_KLEP7
Sequence: MSFLKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDVPAVVMHYGVFIQNVFDFIIVAFAIFMAIKLMNKLNRKKEEAPAAPPAPSKEEVLLSEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPF_STRS2
Sequence: MATTITMQSSTILGNFILVTASFAVLIILIRVFAWDKITGIFEERANKIANDIDAAEEKLTAAANLVQQREDELVQGRIESQKIIQDAVERAKLEKKRILEQADVEIQGLKQKAQLEIEAEKREAQENLRVQVAELAVDLASKIILEDLDQQAHSNLIDRYLDKLGDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL34_RHILO
Sequence: MKRTYQPSKLVRKRRHGFRARMATKGGRGVVAARRNRGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ENO2_LACGA
Sequence: MSVITDIHAREVLDSRGNPTVEAEVYTELGGFGRAIVPSGASTGEHEAVELRDGDKSRFGGQGVLTAVENVNGEIAKAVIGLDVTDQRLIDQTMIDLDGTPNKGRLGANAILSVSLASARAAADELGLPLYEYLGGPNAHVLPTPMMNVINGGKHADNNVDIQEFMIMPVGAKSLHEAVRMGAETFHTLKGLLQERGESTAVGDEGGFAPNLKNNEEPFEILVEAIQRAGYKPGQDIAIAFDCAASEFYNKDTKKYVTVADGREYTAEEWTSLIEDLVDKYPVISVEDPLDENDWEGWKTFTERLGDKVQIVGDDLFVTNTSYLEKGIKMGVANSILIKLNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEEALGSTAQYKGIHSFYNLHKQF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 2, 2-phospho-D-glycerate hydro-lyase 2, 2-phosphoglycerate dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: AMPO_RAT
Sequence: MDINLDPSRDDLPLMANTSHLLVKHYVLDLDVDFGSRVLEGNIVLFFGDGNRCKKQSSSSQETFQMESEEAYILRTAEPCHVPKMDSNTFSPKMGHREFAVFGKSDQDAFDNDGNHDNKEHDSESSSSKYCCDTGNHGREDFLLVLDCCDLSVLKVEEVDVAAVPDLEKFTKAPNLTAAPEKRRCEIVRDLVALPADAWREQLDCYTRCSQAPGCGELLFDSDKWSLQIRKKGVPTAADFPHAIRIWYKTKPEGQSVTWTSDQDGRPCVYTMGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGEKSAKPTPLREGYMSWHYYVTMPMPASTFTIAVGCWTEMKPKTSPLDDLTEHTLPLRPSDADFRYGNTCSHMEYPCRFQSASAATQNIIPYRVFAPVCLEGACREALLWLIPSCLSAAHSVLGTHPFSRLDILIVPTNFPSLGMASPHIIFLSQSTLTGTSHLCGTRLCHEIAHAWFGLAIGARDWTEEWLSEGFATHLEDIFWAEAQQLPPHEALEQQELRACLRWHRLQDELQNSPEGMQVLRPNKEKTGHVSASGASVVKNGLNPEKGFMQVHYLKGYFLLRFLARTLGEETYFPFLRKFVHLFHGQLILSQDFLQMLLESIPENKRFGLSVENIVGDWLECPGIPKALQEERKAKDCSPSRLVRQVGSEVAKWIRVNRRPGKRQRRKREAAFEKLSPDQIVLLLEWLLEQKTLSPQTLHRLQQTYHLQEQDAEVRHRWCELVIKHKYTKAYDQVKRFLQEDQAMGIYLYGELMVSEDARLQQLAHRCFELVKGHMDKASAQVVTEMLF
What is the function of this protein?
Aminopeptidase which catalyzes the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates.
What are the official names of this protein?
Aminopeptidase O, AP-O.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MUG_ECOSE
Sequence: MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQAGFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELDQALVVRGR
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO26_BPHC1
Sequence: MEKTQAQSLLEKLTGNLKDSVTLNVAGVDFTFIRDNAAYDQMLNDIESNNKVTPIKDYLLAIVAREQKEALLEIIHVPTLAAQLAAKVNEVFVPEIQITVKN
What are the official names of this protein?
Uncharacterized 11.3 kDa protein in lys 3'region, ORF26.