PharMolix/UniProtQA huggingface dataset:
Protein: NCX9_CAEEL
Sequence: MCSSEECLIDKSWTSEEKCEYIKCNQDSCEGGGYLTWSHYVKCQYNIGVRVILIILGILYLIILFVIMSSIADDFFCPAISGIVSHLRMSESIAGVTFLAFGNGAPDVFSSISSVLTTPKPKADLALGDLFGTSIFVTTVVLAIIIFTKSFKVAIIPTLRDLIFYMTTLAFIVFCFLKFDKIEVWMPATFLGIYGVYVVTVIILGIYRTHRKKRNLKKKNKELEDFLSRPSSAASTTPIFGAMKLKEETISVSALFHFMIGYSQFIKNLTRANLKRTTNNNNNDNKNEKRGIVNLGFSEPYSIPSERKISTIFKQNTFETDLESLESLADLDGSDDEGREEKFGYAHHTVFTSHDQISLVASEIEEIEITTWRSWDWVWDLFNHLKSWPSRDEFSEMNIFIKIVTVIKVVPVFFFKLTVPSNEMSWCKPLFILHCFASIQFALFSIQIITLKPFDGSPGLWLYGLGFSAILAMVAMYFLPLSKEQKYYKEIYSYLGFLMSIAWIYATSNEIVSVVTMIGVVTGLSMELLGLTIMAWSNCIGDIVADIAVVKQGYPKMAMAAAIGGPLFNLLIGFGLPFTIAAAQGKEMELLINPVYRLLMLFLGISLVTTFVALFIQRFTVRRPHAVLLIFIFVVFLIFICLAEFHVLEWN
What is the function of this protein?
Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis (Probable).  Required for patterning of neural circuits: functions in the same pathway as RAC-dependent effectors of the unc-6/netrin signaling pathway to set left/ right patterning of the VD/DD GABAergic circuit (PubMed:28196860).
What are the official names of this protein?
Mitochondrial sodium/calcium exchanger protein, Sodium/calcium exchanger 9.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MENE_BACP2
Sequence: MMKQPNWLLHRAYVTPERVALIYQDKKWTFRDLADEVNELSNRLAQTSLKKGEAVGLLMNNHPQMVMLVHACFSLGFKIVLLNNKLTKAERRFQLEDVKAAALFTEPVYASDHKGELPVYTMETLPEAGQENVKKIENDFDLNQTATIMYTSGTTGRPKGVEQTFGNHFHSAVSSALNMGLREDDRWLIALPLFHISGLSALFKSVIYGMTVVLHQKFDVDEVIGSIEQHRVTMISVVQTMLSRLLSRLEECPSSLRCLLLGGGPAPLAMLQESKEKGFPVFQSYGMTETCSQIVTLAPEFSVEKLGSAGKPLFGCELKIQDGTRICRPFEHGEIMVKGANVMKGYLYREESTAAAFDQGWLKTGDIGYVDEEGFLFVLDRRSDLIISGGENIYPAEIEAVLLTHSHVKEAGVTGIDDDRWGEVPAAFLVTDHKIPENELYALCESHLAKYKWPASFHFVDELPRNASNKLQRHRLKSKGFLDDSN
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: RS9_RHIE6
Sequence: MADLSSLKDLGTASEAAAPAHVRKVDSLGRSYATGKRKNAVARVWVKPGSGKIIVNGKEFADYFARPVLQMILRQPIVAAARDGQFDIVATVAGGGLSGQAGAVRHGLSKALTYFEPGLRSVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: GLMU_ANAMF
Sequence: MDIVILAAGCGSRMCSTTPKILHKLGNAPIIKHVLQLADELRPKRAVIVTNAAVNGPVAALAGEHNLRLNTVLQGEIAGTGGAATSALQALKNPSEEIVLILYGDTPLLDKATVCHALDRLSSGAKIVLVAFKSENNQYGRIVLGSSGNVLEVSHGRDTNGLAVSGAIAGYRQVISGLLGGLSCRDGELYLTDIVQSAAEKNVEVGYVIADERKAMGINTRADLAIAESYFQCMKRASFLQSGVTLTSPDQVFFSIDTQIAQDVIVHPYVVFGAGVAVEPGAEILSYSHLEFCHIKKGAIVGPFARVRGNSTIDRGCVVGNFVEIKESSLGEMSKVKHLSYLGNSTIGKNTNVGAGTVICNYDGRNKQHSDIGNNCFVGANSTIVSPIKVGDNAAIAAGSVITEDLPPRSLGIARSRQTTKPEYKTRR
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1M_PELSU
Sequence: MSIMMNLLQPLAFILPILIAVSFFTLVERKVISCMQPRKGPNITGPFGLLQPLADGLKLLFKEPVYPTNSSTTLFILTPTMALSLALSTWLPMPLPFSLVDLNLGLLFLLSMSSLMVFSILWSGWASNSKYALMGALRAVAQTISYEITLSLILLSMVLFSGGFNMRTFMTTQEQIYLIFSSWPLAMMWYISTLAETNRAPFDLAEGESELVSGFNVEYAGGPFAAFFMAEYTSILMMNTLSTILFLNPGFMYTSPTIFSISLMTTAVALSMGFLWIRATYPRFRYDQLMHLLWKNFLPITLAWCLWHISLLVTTSGIPPML
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RIR1_AQUAE
Sequence: MTMYVIKRSGRKEKLDINKIRIAIKFACEGLNVDPLELEADAQIQFRDGITTKEIQQLLIKTAAEKVSAERPDWTYTAARLLLYDLYKDVAHLRGYSLRDDLGKYKPYNRKNFYSFVKEYVEKGIYGEYLLENYSEEDFNKLANYIKPERDLYFTYTGIKILYDRYLVRDEEGRVIELPQEMYMLIAMTLAVPEKPEERLKWAKKFYDVLSEHKVTVATPTLMNARRPFTQLSSCFVLTVDDDLFDIFDNVKKAGMISKFAGGLGVYLGKIRATGAPIRKFKGASSGVIPVVKLINDTMTYVDQLGMRKGSASITLDIWHKDILDFLEVKTNVGDERKKAHDIHPAVSIPDLFMKRLKNREDWTLIDPYWARQYITRKIYDGKYKEVKPLPGSHYYVGIKEDGTQDILEPKGLEDFYGEEFEKWYLELEENLPSYAKKKVNSFELWKRLLTVAFETGEPYIFFRDEANRKNPNKHTGMVYSSNLCHEIVQTMSPSKHEKPVLDPETGEITYKKEAGDLPVCNLGSVNLGKVHTEEEIKEVLPLLVRMLDNVIEMNFYAIPEAEYTNKRYRAIGIGVSNYHYCLVKNGIKWESEEHLKFADKLFELIAFYALKGSLELAKERGRYKLFDGSNWSKGILFGRSVEEIEENSRQNGNNLPWRELAEEIKKYGIRNAYLLALMPTGSTSLILGATPSIDPIFARFYKEENMSGILPQVPPEVDRFYWHYKTAYTIDHEWTIRAAAVRQKWIDQAQSLNLFVDPQNIDGPRLSRLYELAWELGLKTIYYLRSRSAMDIEECEACSV
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit alpha, Ribonucleotide reductase.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: PYRH_LIMRT
Sequence: MSDIKYNRVILKLSGEALAGEKGFGINPPVLKDVAKELKEVHELGVQIAIVVGGGNMWRGVTGAELGMERAQADYIGMLATIMNALSLQDALESLDVPTRVQTSIEMRQIAEPYIRRKAIRHLEKDRIVIFAGGTGSPYFSTDTTAALRAAEINADAILMGKNGVDGVYNADPNKDASAVKFDHLTHMDLIEKNLHVMDTTASSLSMDNHIPLVVFNLNTPGNIMKVVKGQEVGTTIEGD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEB_ECOUT
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDIIAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: LEXA_XANP2
Sequence: MLTRKQYDLLRFIHERLKETGVPPSFDEMKEALDLRSKSGIHRLITALEERGFIRRLPNRARALEVVRLPDSVAPGLATPRSASRGFSPSVIEGSLGKVRPAADDDEGAGQVVTVPVMGRIAAGSPISAIQTRSHTLNIPPEMLGSGEHFALEVRGDSMIEAGILDGDTVLIRKCDTADTGDIIVALVDDEEATLKRLRKKGASIALEAANPAYETRIFGPDRVRIQGRLIGLMRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: PANC_DESPS
Sequence: MKKISSRQEIREQVKKWQEQGLTVALVPTMGCFHQGHLSLIKKGREIADRLIVSLFVNPIQFGPGEDLDAYPRPYEKDSRLAEELGTDVLFCPETTEMYGPNFQTNISVTTLTADLCGAGRPGHFDGVATVVTKLFHLCQPDFAIFGEKDFQQLAMIKQLVIDLDFDLQIISCPIYREDDGLAMSSRNKYLNAEQRLKALCLSQALEVAKDYVLARSAAGKTIESDEVITKARGVIIDAGYEPEYISIVDQQTLEPSPTVQPGNVMALAVRIAERIRLIDNSALLT
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_STRP1
Sequence: MLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSVKSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: YAEH_ECO7I
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: PRIM_EHV1V
Sequence: MAQRNPEPTIRVLYATDSCVITYSLMLLTGQESSEGVYAISYDWSSELDDLFGRQPRAPNTDAGDGWSSTEQSDADQLATALLQRKPSVSFCLLSGMVGGASDEPQDRVRPMFVCVFSTWTGARALAMTLSHGHPLSSNTLLQALTEEATFLLHNDLILALAITTENVTARSGRTAAAAKYDPQRGSVKAAVIGHSTGRSGLTSVYIHHENKVLTAFRRLYCNNNTTPFWFASKFGPGEREIVLATRYYLFQAIRCSRSGGTYDLQAVKDFIRTYNVPAAPNPTGLDLTHLTSFSLLSKFCCQSWYSRGPCALALPRYVDLRIQADVAEVSALEGFIAADRQGLRVSDREFITYIYLAHFESFNRKQLYDHLLAVSIADPGDIDRITSTSSLKRGTIEKFFAQVRIQLNIRDYIAHNVNPRVVCLPASIGSQYAQDKTYTPSSTTMSTGSAPLGVCDTSTPILKLLDRVESSLAGRGWIQTIVSPNKPQSVHSTPPLDQSRGDELSPGVSSQCGISRRLLHIASSPPVNGRALPLEVLFGQKGVPGPAPVYRVALPSKRQAFAVIANDRWETTTQNLARPGGSKQAYEGGFALAGFGEIDDCSLAWRDLQLTRTTSGVCRTALASSNASAQMYINRNEIFNSSLAVSNIILDVDFGIKRRVPLGMLHLAMRGFRAGIITTLSLIFSDATVQWDSYPCYFYKTSCPPQLVRALHRGEPSSFPDYVDGVEECYMESDFIDDYAAMEEYTDGPMDDYEMMMVDNECPQAACDNTPPNKEGGKTPLQRLDDTDACECTEKMGFRVTVPVPPPYLLAGPEALRGLARIIQQAVVLERTFTESMCSVLRDFSFIDTGVYSHGRSLRLPFFCKVGDSGEVYGGLYPFYVIPPKCNDVDEFVAQHSNPANFHFHAAPRHPTITHVITDLGGDYVSFFERKVARNREAIMTKRATLESLLSSANVSIKSHEAVEAFVVDVVLGEVVSHLATHFPDQSGEYQTVGVHTVVTKPDWILMQINRSGNAYRSQGFSCLRAKHLRSARGLARTFLSISADVHGRLCASISQQCFATKCGNNKMCTIFTLEVDRAK
What is the function of this protein?
Essential component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA primase family.
What are the subcellular locations of this protein?
Host nucleus. Note=Requires the presence of the primase associated factor to properly localize in the host cell nucleus.
Protein: HBSAG_HBVGO
Sequence: MGQNLSTSNPLGFFPEHQLDPAFKANTNNPDWDFNPNKDNWPKANEVGVGAFGPGLTPPHGGLLGWSPQAQGIITTVPANPPPASTNRQSGRKPTPISPPLRDTHPQAMHWNSTTFHQALQDPRVRGLYFPAGGSSSGTAYPVPDTASHISSIFSRTGDPAPNMESITSGFLGPLLVLQAGFFLLTKILTIPQSLDSWWTSLNFLGGAPVCLGQNSQSPTSNHSPTSCPPICPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSTTTSTGPCKTCTTTAQGTSLYPSCCCTKPSDGNCTCIPIPSSWAFAKFLWEWASVRFSWLSLLAPFVQWFAGLSPTVWLSVIWMMWYWGPNLYNILSPFIPLLPIFFCLWVYI
What is the function of this protein?
The middle envelope protein plays an important role in the budding of the virion.  It is involved in the induction of budding in a nucleocapsid independent way.  In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid.
What are the official names of this protein?
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus major surface antigen family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: RRAA_HAEDU
Sequence: MRIDTSALCDIYSDQVDVVEPIFSSFGGASSFYGKITTVKCFENNGLIAEVLEEEGEGRVLLIDGGGAVRRALIDAELAKLAVDNGWQGIIVYGAVRQLDVLETLDIGIHALAPIPVGAEDADIGEVDTPVNFGGVTFFPEDYVYADLTGIILSPELLDLNELAE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED1_DICDI
Sequence: MDHHKQLTLQTTLESCNNLYNLLFNSIGSIKPSQQQQQQQQNQKNTNSVTSNTNIINDQEIFKLNKFHLYGENNIDELYNSIELQLQTIKFTCQQYRQWDSTERDSIKFFNTQKLYNQSQQRGNLVSKTLFDCSLLGKIYLNQQKEQQQQQKQKNKQQQQQPQPLVEDLSKNISKTVEVKRKLGLLAGKLQEMTNELNNKYSTFSVLDDLLGLLKSNTEIDYNSDSYVSCNISSSTFLLDIDIYHNGEIKEVKLVHILTTTGEVEPAEQQFNDELTNSLKTDMKEFIKKVQRICDLDLLFRKYKHFDLQKAFSILQSDFLNISINSNIKYIDNKEIEMNKGFGEIKLDCCGVLIKYFQSYIEKISKMNEPYSIMIEMESSAVTNNGSLIDQSEYSRLSLKTLLQKQQHTQPSAQTDYSEQQQQQSISTQLTSIEFNEKDCLDCEPLSSMLESDSIFSPVRLVCKLNKPILITNQQLSKILNLSKIHRSSQQPSQQQPSQQQQQQQQQQQQKKLNSVDESMNENGDSNIIENINELIKKYSIQNLLISSSSSSSSSNDSNISVNVDNSFDCEVYGMKQRYYYTGEFELGIEISRIPIYHPSQVYPTIQLLRQQIVFNILFKSCFQNLNISKSDDHHNIIDNNNDVKIFEITSNPPNSINIIFLHPIDNSFNSIDIFIKNNGDLEAFYYDNTTNIQPNIQKSTLFTKMLIKSLSISVSLACFFKNK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Putative mediator of RNA polymerase II transcription subunit 1, Putative mediator complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HGD_RHOPT
Sequence: MNINAAPQILGRSSQDITPGYMSGFGNSFETEALPGALPVGRNSPQRCAYGLYAEQLSGSPFTAPRGANERSWLYRIRPSVKHSGRFAKTDMGLWRSAPCFEHDLPIAQLRWDPPPMPQEKLTFLQGVRTMTTAGDVNTQAGMATHLYLITQSMVDQHFYNADGEMMFVPQQGSLRLVTEFGIITIEPAEIAVIPRGIKFRVELVDGPARGYLCENYGGAFTLPERGPIGANCLANSRDFLTPVAAYEDKDTPTELYVKWGGSLYVTKLPHSPIDVVAWHGNYAPYKYDLRTYSPVGAIGFDHPDPSIFTVLTSPSETPGTANIDFVIFPERWMVADNTFRPPWYHMNIMSEFMGLIYGVYDAKPQGFVPGGASLHNMMLPHGPDREAFDHASNGELKPVKLTGTMAFMFETRYPQRVTEYAASSGLLQDDYADCWNGLEKRFDPNRP
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: QUEA_BURO0
Sequence: MFTLSDFDFNLPPELIAQTALPDRTASRLLEVDGSVAPARLVDRHFAELPSCIAPGDLLVFNDTKVLKARFFGQKASGGKIEVLIERVTGTHTALAQIRASKSPGAGTTLRLADAFDVTVGERVEPFFTLHFPAPCLDLIEQHGRLPLPPYIEHDADATDETRYQTVYASNPGAVAAPTAGLHFDQPLLEKLDAMGVERATLTLHVGAGTFQPVRVENIAEHKMHSEWYDLPQSLVDKIAATRARGGNVIAVGTTSMRALEAAARSADEAGRPLAATQAETDIFITPGYRFRVVDRLVTNFHLPKSTLLMLVSAFAGVETIRAAYRHAIEERYRFFSYGDAMLLTRRDTPEAPGA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
Protein: CANB2_HUMAN
Sequence: MGNEASYPAEMCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRRVIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLKMMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEFSAVVRDLEIHKKLVLIV
What is the function of this protein?
Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase.  Confers calcium sensitivity.
What are the official names of this protein?
Calcineurin subunit B type 2, Calcineurin B-like protein, CBLP, Calcineurin BII, CNBII, PPP3R1-like, Protein phosphatase 2B regulatory subunit 2, Protein phosphatase 3 regulatory subunit B beta isoform.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Localizes in the mitochondria in a SPATA33-dependent manner.
Protein: CLPP_OENEH
Sequence: MPIGMPKIPFLLDGDEEDEEEDDATWVDLYNVLYRTRSIFLGDAIHFEVANHIAGLMIFLTIQDATQNLYFFINSPGGLAVAGLLIYDTMQYVTPPVYTLGLGVLASMASFLLVGGETSKRLMGPNGRVMIHQPESDYTHKDQSLEVQLDSGEVEDIRKMVIRVYLERTRLPREVLNDHLERNYFMTATEAKYYGIVDDIGIQNLLARLRAESASQDNSLDPDAPDESASQDNSLDPDAPDETRPPKLR
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RHD3_ARATH
Sequence: MDAACSTQLIDGDGVFNVSGVDHFIKEVKLDECGLSYAVVSIMGPQSSGKSTLLNHLFGTNFREMDAFRGRSQTTKGIWIARCAGIEPCTVVMDLEGTDGRERGEDDTAFEKQSALFALAVSDIVLINMWCHDIGREQAANKPLLKTVFQVMMRLFSPRKTTLMFVIRDKTRTPLENLEPVLREDIQKIWDSVPKPQAHKETPLSDFFNVEVVALSSYEEKEEQFKEQVYNLRQRFFQSVAPGGLAGDRRGVVPANAFAFSAKQMWQVIKDNKDLDLPAHKVMVATVRCEEIANEKFSSFIANENWRELEEAVQSGPVSGFGRKLSSILQASLSEYDTEATYFEESVRSSKRQQLQEKLLQLVQPTFQDVLGHLRAGALENFKNAFEKALDAGEGFSSSAKSCAQSCISKFDKGCEEAVIEQAKWDTSKTREKLERDIEAHISSVRTAKLAELTTLYESKLNVALSGPVEALLDGANDETWPAIRKLLRREGELAVYGLSNALSGFEMDEETRSKMLADLENYARGIVETKAKEEAGRAMMRMKDRFATIFSHDSDSMPRVWTGKEDIRAITKMARSASLKLLSVMAVIRLDDELDNIEKTLTLALFNSTGNNATSKSISTIDSLASSTWEKVAPEKTLITPVQCKSLWRQFKNETEYTVTQAISAQEANRRNNNWLPPPWAILALVVLGFNEFMTLLRNPLWLLVLFVGYLVSKALWVQLNISGEFQNGVLPGLLSLSTKFIPTVMNLLKKLAEEGQAPPTNSNQSMNSTAQSEVTTNGESSSSSSSGSSPAKNVPIDTSA
What is the function of this protein?
Probable GTP-binding protein involved in cell wall expansion.  Required for appropriate root and root hair cells enlargement.  May inhibit vacuole enlargement during root hair cell expansion.  Plays a role in cell wall biosynthesis and actin organization.  Seems to act independently from auxin and ethylene pathways.  May regulate membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).
What are the official names of this protein?
Protein ROOT HAIR DEFECTIVE 3, Protein FRAGILE FIBER 4, Protein SEY1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane.
Protein: RS4_CHLAD
Sequence: MARFRGPVGKVSRRLGIGITEKGQRILNKRPDPPGQHGAAARRRALSDYGAQLREKQKAKFIYGVLERQFRRLFEQAARRSGVTGEYLLSLLERRLDNVVYRLGFATTRAQARQLVNHGHIVVDGRKTNIPSYTVKVGQVIAVRPQSRSRTYFKNLVDSGVLNKHRAPEWLRLNPAELSGTVVALPRREDAEAGINEQLIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ISU1_ORYSJ
Sequence: MLRAGGRRLLAPGLRRVLGGGAAAPVAVGGAKAYHERVVDHYENPRNVGSFENDDPSVGTGLVGAPACGDVMKLQIRVDESSGKIVDACFKTFGCGSAIASSSVATEWVKGKQMEEVVTIKNTEIAKHLSLPPVKLHCSMLAEDAIKAAVKDYEAKKAKLAQKGEEKAAEA
What is the function of this protein?
Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (Probable).  First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISCU (ISU1, ISU2 or ISU3).  In a second step, the cluster is released from ISCU, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins.  Cluster assembly on ISCU depends on the function of the cysteine desulfurase complex NFS1-ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity).
What are the official names of this protein?
Iron-sulfur cluster assembly protein 1, OsIsu1.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GLYA_NATPD
Sequence: MNYEQVREADPAIAAALADERDRQEDTLAMIASENHVSEAVLQAQSSELTNKYAEGYPGERYYAGCGPADDVEELAIERAEELWGAEHINVQPHSGTQANMAVYLAMLEPGDRILSLELEHGGHLSHGHPANFTGQTYEVEQYEVDPETGYIDYDELHEQAEAFEPDIIVSGYSAYPREVEFERIQEAADAVDAYHLADIAHITGLVAAGVHQSPVGVADFVTGSTHKTIRAGRGGIVMCDEEYADDIDAAVFPGAQGGPLMHNVAGKAVGFKEALQPEFEQYAQQVIDNAEALGERLQEHGFSLVSGGTDNHLVLVDLRESHPDTSGTVAEEALEAAGIVLNKNTVPGETRSAFNPSGIRAGTPALTTRGFDEQACERVADIIANVIDNPDDEGTIDEAAAEVDALCEEYPLYQGESGITDFE
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CROS5
Sequence: MIQQQTYLNVADNSGARKLMCLRVLGTGNCRYGEIGDKIVAVVKDALPNMPIKRSDIVTAVIVRTRQPVNRASGMSIRFDDNAAVIINADGNPRGTRVFGPVARELRDKSYTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.