PharMolix/UniProtQA huggingface dataset:
Protein: GALT7_PONAB
Sequence: MRLKIGFILRSLLVVGSFLGLVVLWSSLTPRPDDPSPLSRMREDRDVNDPMPNRGGNGLAPGEDRFKPVVPWPHVEGVEVDLESIRRKNKAKNEQEHHAGGDSQKDIMQRQYLTFKPQTFTYRDPVLRPGILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYFYASRPESQALPYGDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKVMITHCNLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV
What is the function of this protein?
Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide.  In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties.  Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified (By similarity).
What are the official names of this protein?
N-acetylgalactosaminyltransferase 7, Polypeptide GalNAc transferase 7, GalNAc-T7, pp-GaNTase 7, Protein-UDP acetylgalactosaminyltransferase 7, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: QUEF_RHOPB
Sequence: MSKTPRKPSQSPALQLGRAVDWPQTPDEAKLDRVPNPQADTDYLVRFTAPEFTSLCPVTGQPDFAHLMIDYAPGAWLVESKSLKLYLASFRSHGAFHEDCTVAIGKRIAQEIKPKWLRIGGYWYPRGGIPIDVFWQTGKLPKGVWVPEQGVATYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_SALPA
Sequence: MTPEHLPTEQYEAQLAEKVARLQSMMAPFSGLVPEVFRSPVSHYRMRAEFRLWHDGDDLYHIMFDQQTKSRIRVDTFPAASQLINTLMKAMIAGVRDNHALRHKLFQIDYLTTLSNQAVVSLLYHKKLDEEWREAATALRDALRAQGLNVHLIGRATKTKIELDQDYIDERLPVAGKEIIYRQVENSFTQPNAAMNIQMLEWALEVTKDSKGDLLELYCGNGNFSLALARNFNRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKRYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHTVSRLALFDQFPYTHHMECGVLLTAR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: CAPZB_GIBZE
Sequence: MAVDPFDSALDLLRRLNPKQTTDHLNAIISIAPDLTEDLLSSVDQPLTVRRCKQTGRDYLLCDYNRDGDSYRSPWSNQFDPPLDEAGSGGVGAGGNEGAGEGAIPSERVRKMEVKANEAFDVYRDLYYEGGVSSVYFWNLDDGFAGVVLLKKSSPQGGNSEGVWDSIHVFEAIERGRSTHYKLTSTVILTLSTSGGNLGEMDLSGNMTRQVEQDLPVENDDSHIANVGRLVEDMELKMRNLLQEVYFGKAKDVVGDLRSIGSLSEGARDREAQRELIGSMRK
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit beta.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Septum.
Protein: PORIM_HUMAN
Sequence: MGLGARGAWAALLLGTLQVLALLGAAHESAAMAASANIENSGLPHNSSANSTETLQHVPSDHTNETSNSTVKPPTSVASDSSNTTVTTMKPTAASNTTTPGMVSTNMTSTTLKSTPKTTSVSQNTSQISTSTMTVTHNSSVTSAASSVTITTTMHSEAKKGSKFDTGSFVGGIVLTLGVLSILYIGCKMYYSRRGIRYRTIDEHDAII
What is the function of this protein?
Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability.
What are the official names of this protein?
Porimin, Keratinocytes-associated transmembrane protein 3, KCT-3, Pro-oncosis receptor inducing membrane injury, Transmembrane protein 123.
What is the protein family that this protein belongs to?
Belongs to the CD164 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CTXA_DICDI
Sequence: MAGKDWEIVQEKAFTAWVNSVLDKRGEKISDVGKDLSDGVKLIFFLELISSKKFNKKYDFEPKARINMIQNVALALKFLDEELKIKVQGIGSEDFVDNNKKMILGFLWTLYRKYRIAVISEGDKSSEEGLLLWCKNTTTGYDGVNITSFTKSFRDGLAFLALSHKFEPESFKFQEFEAMDPIARLNAAFDFAEKGLGVPKLLEAEEVMRGTTDERSLVLYTSLFFHAYRAKEEKARLESSKNEMANRLAGLENSLESEKVSREQLIKQKDQLNSLLASLESEGAEREKRLRELEAKLDETLKNLELEKLARMELEARLAKTEKDRAILELKLAEAIDEKSKLEQQIEATRIRGAAEAQGLGLLRKNLDTHVHDLLKWQKLTMENSSSSSIDDQIIVEVSGLPFGEQVKHLATKLEAENLAIMKLLNQKEDDLKAQKLKSSKSKK
What is the function of this protein?
Actin-bundling protein.  When linked to F-actin the actin filaments form preferentially anti-parallel bundles that associate into meshworks.  Plays a major role in cytokinesis.  Negatively regulates cortical localization of rapgap1.
What are the official names of this protein?
Cortexillin-1, Cortexillin I.
What is the protein family that this protein belongs to?
Belongs to the cortexillin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TVBL4_HUMAN
Sequence: MGSWTLCCVSLCILVAKHTDAGVIQSPRHEVTEMGQEVTLRCKPISGHDYLFWYRQTMMRGLELLIYFNNNVPIDDSGMPEDRFSAKMPNASFSTLKIQPSEPRDSAVYFCASSL
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 12-4.
What are the subcellular locations of this protein?
Cell membrane.
Protein: COQ7_METPP
Sequence: MRSLSRTDQVISSLDKALSTVFAAHSASRPAPKPAVDPGLAMTPQDKSLSASLMRVNHVGEVCAQALYASQALGTRNETLRAQFEHAAREETDHLAWTEARLAELNGRTSWLNPLWYAGAFGLGLIAGRLGDAASLGFVVETERQVEQHLLQHLDRLPVADVESRAIVAQMREDEARHAAAAEHAGAATLPVPVRWMMRGMAKLMTSTAHRI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TSAC_SHEON
Sequence: MLQLHPSDIKDVVLNGGVIAYPTEAVYGLGCDPDNDTAIQKLLAVKQRPWQKGLILVASEFSQLLAYVDESQLTDEQLELAFSKWPGPFTFVMPIKPHVSRYLCGEFDSIAVRVSAHEGVRALCQALGKPLVSTSANLAGEDPALSGDEILNVFEGKIDALVLGQLGEQRQPSTIIDARSGKILRNGQ
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_BACAH
Sequence: MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTAEEAKGLQAKEVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKEFLLKAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGEVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWSTATI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_LISIN
Sequence: MLKPLGDRVVIEVLEAEEKTASGIVLPDSAKEKPQSGKIVAVGSGRVLDNGTKEPLEVAEGDTVIFAKYSGTEVTYEGTDYLILRESDILAISK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP1C_OXYTA
Sequence: FRGLAKLLKIGLKSFARVLKKILPKAAKAGKSLAKSLADENAIRQQNQ
What is the function of this protein?
Disrupts cell membranes, particularly those rich in phosphocholine, through formation of pores.  Has antimicrobial activity, hemolytic activity and insecticidal activity.
What are the official names of this protein?
M-oxotoxin-Ot1c, M-OXTX-Ot1c, Oxyopinin-1c.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 02 (oxyopinin-2) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a transmembrane alpha-helix in the target cell membrane. Forms a membrane channel in the prey.
Protein: PUT1_YEAST
Sequence: MIASKSSLLVTKSRIPSLCFPLIKRSYVSKTPTHSNTAANLMVETPAANANGNSVMAPPNSINFLQTLPKKELFQLGFIGIATLNSFFLNTIIKLFPYIPIPVIKFFVSSLYCGGENFKEVIECGKRLQKRGISNMMLSLTIENSEGTKSLSSTPVDQIVKETISSVHNILLPNIIGQLESKPINDIAPGYIALKPSALVDNPHEVLYNFSNPAYKAQRDQLIENCSKITKEIFELNQSLLKKYPERKAPFMVSTIDAEKYDLQENGVYELQRILFQKFNPTSSKLISCVGTWQLYLRDSGDHILHELKLAQENGYKLGLKLVRGAYIHSEKNRNQIIFGDKTGTDENYDRIITQVVNDLIINGEDSYFGHLVVASHNYQSQMLVTNLLKSTQDNSYAKSNIVLGQLLGMADNVTYDLITNHGAKNIIKYVPWGPPLETKDYLLRRLQENGDAVRSDNGWPLIKAIAKSIPKRVGL
What is the function of this protein?
Converts proline to delta-1-pyrroline-5-carboxylate.
What are the official names of this protein?
Proline dehydrogenase, mitochondrial, Proline oxidase.
What is the protein family that this protein belongs to?
Belongs to the proline oxidase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PTH_RHOCS
Sequence: MRLVVGLGNPGPEYERQRHNVGFMAVDLLHRRYGFGPWKRRFQGLTAEGSVAGEKVLLLKPATFMNLSGQAAGEAMRFYKITPDQVLVFHDELDLPPGRVRVKRGGGHGGHNGLRSLDDHVGKDYWRIRIGIGHPGSKERVTGWVLSNFAKAEEQWLEPLLDALVAEAPLLVAGEPEKYASRIALLTQPPKPPKPPKPPKDGAKETAGKGTEAETAKPPGPAAGRTG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A1E_MOUSE
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-E.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: AMPA_TRIV2
Sequence: MAIQLSDKPLLEWAGDTLAIALFEDAVELTGELASLDEKFAGILKELIAEEEFTGKANSTVFTRVSANIPVRKIILVGLGKTEAFNIDTLRRAAAAVGKVGKKQKSKVIGLSFPLWNNDPTASSQAIAEGVQLALYQDNRFKSDPDDKGSQVETVELLGFAGQEAAINRANQIVSGVILARQLVAAPANSVTPITMAETAQQIAQDYGLQIEILEQEDCEKLGMGAFLGVALASDLPPKFIHLTYKPESTPKRKLAIVGKGLTFDSGGLNIKGAGSGIETMKIDMGGAAATLGAAKAIAQIKPNVEVHFISAVTENMISGKAMHPGDILTASNGKTIEVNNTDAEGRLTLADALVYTDKLGLDAIVDLATLTGANVIALGDDIAGLYTPDDALAGQLEQAASESGEKIWRMPLEEKYFEGLKSGIADMKNTGPRPGGSITAALFLKQFVKDTPWAHLDIAGPVWADKENGYNGPGATGYGVRLLVDWVLSE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIT_SULIA
Sequence: MEWKYVIPGIPDNFFERDEEIPMTKEEIRALALSKLRIRKGDMILDIGCGTGSVTVEASLLVGSTGKVYGVDKEEKAINLTRRNAEKFGVLNNIVLIKGEAPEILFTINEKFDRIFIGGGSEKIKEIISASWEIIKKGGRVVIDAILLETVNNAISAMENIGFMNLEITEVIIAKGMKTKVGTAMMTRNPIFIISGEKQ
What is the function of this protein?
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
What are the official names of this protein?
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
Protein: YQGF_SYNP6
Sequence: MPYYAALGLDVGRRRIGVAGCDRLGITVQGLTTIVRRDFASDVAAISAIAKERQVELLVIGLPYSMDGSLGSQAKQTQRFATRLSKALQLPITYVDERLTSFEAEEMIKAVGRSPSRDKGAIDRKAAALILQQWLDEQREPRRFGSTQH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_BUCRP
Sequence: VAAAIACALFNLKCKIYMGYKDIKRQSPNVFRMKLMGAEVISVENGSGTLKDACNEALRDWSRNYQKSHYMIGTAAGPHPYPTIVKEFQKMIGEEAKKQILEQENRLPDAIIACVGGGSNAIGIFSDFIDEKVNLIGVEPAGKGIETGKHGAPLTHGRTGIYFGMKSHLMQSQEGQIEKSWSVSAGLDFPSVGPEHSWLNSINRAKYVSVTDIEALEAFQILSKK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: GLMU_HAEIE
Sequence: MTKKALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGAENIHLIYGHGGDVMRTHLANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIDAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANADQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYLQNKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGAGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPIKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLAG_MACLB
Sequence: MGRLISVSFGLLVVFLSLSGTGADQDCLPGWSFYEGHCYKVFNVKKTWEDAEKFCQKQSNGKHLATIEWLGKANFVADLVTLMNSDPDLDWIGLRVEDKRQQCSSHWTDGSAVSYENVVHNTKCFGLDQKTGYRTWVALRCELAYHFICMSRVPRGA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec A16, C-type lectin A16.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC_PORCN
Sequence: VLRYRGIVCDRCGVEVTEKKVRRERMGHIALEVPVAHIWFFRSIPNKIAYLLGIPSKKLDAIIYYERYAVIQPGTVEGLAAGDLLTEEEYLDILDSLPEGNQDLEDDAPEKFIAKIGAEAIYDLLCRVDLDKLSYELRAKASKDSSQQRKKEALKRLQVVESFRASEGYSRPEWMVMKVIPVIPPELHTLVPLDGGRFATSDLNELCRRVIIRNNRLRRLIEQRAPQVILRNEKRMLQEAVDSFFDNSSKAGAVKSDSNRPLKSLTDSLKGKQGRFRQNLLGKRVDYSGRSVIVVGPEPKMHECGLPKYMAAELYKPFVIRKLLERGIVKTVKSARRIVDKKGPEVWDILEHVIKGHPVLLNRAPTLHRLGIQAFQPKLIEGKAIQLHPLACTAFNADFDGDQMAVHLPLSNEAILEAQMLMLASHNILNPANGAPITVPSQDMVLGLYYITKLRKDAKGAGLVFYGREEATIAYNDGKVAIHAPIKVMVDDVDADGNPIRHLVETSVGRLMFNECVPQGVGYINSILGKKALRDIIGHVIKECGIAKTAKFLDDIKDLGYQMAFKGGLSFNLSDVLIPKEKDTLIQEGFAEVDEIMSNYNMGFITNNERYNQIIDTWTHVNTCLSGILMKQLSEDNEGFNSIFMMMDSGARGSKDQINQLSGIRGLMAKPQKSGTEGRTLLENPILSNFKEGLSVLEYFISTHGARKGLSDTALKTAECGYLTRRLVDVSQDVIVTEEDCGTLRGLVTEEIKEGDVVIASLYERILGRVSVHDVIHPNTGEVIVKAGEEINEKAATIIQDSPITNVEIRSVLTCESKKGVCAKCYGRNLSQGHMVHIGEVVGVVAAQSIGEPGTQLTLRTFHTGGIASNIGSEKYVKAKYDGILEIDELRTVDAKDEEGNAYQVVVGRLAEMRVIDENTRMTLITHHIPYGSKLYFKPGDKVKKDDNIFESDPFNAVIIAEETGKLKFEDVVENVTYKVEYDSNVSAGHKEHIIIESKDKNLSPSVSILNSKGDILRTYNLPVGAHFVKSNGDSVKTGDVLVKIPRSTLKGGDITGGLPRVTELFEARNPTNPAIVAEIDGEVSLGRVRRGNREVTITSKLGEERKYLIPLSKQLLIQENDYVRAGMPLSDGAITPADILAIKGPNAVQDYIVNGVQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: TRUD_SALSV
Sequence: MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RNH2_THET2
Sequence: MAEGPLEAPFWRKGLLVAGLDEAGRGAWAGPIVVGVVVLPPGEYPFRDSKLLSPRARERLAEKVKEVALAFALGVAEAAEVDRLGVLKATLLAAERALLSLPLAPEALVTDYLPLPTPLPLLSPPKADEKSPTVAAASILAKVHRDRIMAELDRLYPGYGFARHKGYGTPEHQEALLALGPSPVHRKRFAPVAQAPLRFPEAP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_LEGPL
Sequence: MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPIGLHIHTIVREDALLLYGFLDKEERSLFRSLIKVNGVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKKTAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISALEALGYKPQEAWKVVNKIDNGNKSCEQLIREALQILSSR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MLF_DROME
Sequence: MSLFGALMGDFDDDLGLMNNHMNHTMNAMNMQMRSMNRLMNSFMPDPFMQVSPFDQGFQQNALMERPQMPAMPAMGLFGMPMMPNFNRLLNADIGGNSGASFCQSTVMTMSSGPDGRPQIYQASTSTKTGPGGVRETRRTVQDSRTGVKKMAIGHHIGERAHIIEKEQDMRSGQLEERQEFINLEEGEAEQFDREFTSRASRGAVQSRHHAGGMQAIMPARPAAHTSTLTIEPVEDDDDDDDDCVIQEQQPVRSSAGRHYSSAPTAPQNSGNIATAAAPTPTSSPTTYDTSNGNNNNYVSSRRSYLRNGHGHSLATPRRPLRTPPSSPLATVSTSPSIHPHPYAANPRRQQRAVKHFHTEDEAASSYKAVKRGKKK
What are the official names of this protein?
Myeloid leukemia factor, Myelodysplasia-myeloid leukemia factor, dMLF.
What is the protein family that this protein belongs to?
Belongs to the MLF family.
What are the subcellular locations of this protein?
Cytoplasm.