PharMolix/UniProtQA huggingface dataset:
Protein: THIC_STUS1
Sequence: MSVQSNKNLSESAQVDQQSIQPFPRSQKIYVQGSRPDIRVPMREISLDVTPTDFGGEINAPVTVYDTSGPYTDPNVTIDVRKGLADVRSAWIEDRGDTEKLPGLTSEFGQRRLNDAELSAMRFAHVRNPRRAKAEHNVSQMHYAKKGIITPEMEYVAIRENMKLAEAREAGLLVEQHAGQSFGAAIPKEITPEFVRSEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMHMIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDETLPKESAKVAHFCSMCGPKFCSMKITQEVREYAAEHGLTDEQKAIEAGFAEQSSRFKDGGSVIYKQV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: POF3_SCHPO
Sequence: MNNYQVKAIKEKTQQYLSKRKFEDALTFITKTIEQEPNPTIDLFELRAQVYEKSGQYSQAELDAKRMIHLNARNARGYLRLGKLLQLDGFDKKADQLYTQGLRMVHKMDPLRPVLKKVSQRLNERILRTRPVLDLFRILPREVLLCILQQLNFKSIVQCMQVCKHWRDCIKKEPSLFCCLDFSCASPRSVNSRDRNVMAVARYSVYSKDNIQEVIGLEKLGILTPTKALLRSVKSLKVYKTISPLHTQSTDKLYTIWTPFSELHYFYCATPITFSIASKILSCCKKLKQVELVDLIPDLIFDSMDWDKLFNAESVPLALKSLTFIRNQKFPFHHKEQQFLKDLLSASPYLEYLEASYQSDLVAAIKKYKINLRSLIIIDEGVSNTVKDLAFLPQSLTTLIVKPCNPASTILCPYLFPTNVRMESLINLELFLYLRLSQNDIDNVVKFLTSCYKLKKLVLHDSLALAPHFFEIFASLPELEHLEIPDNVALQNKHAIHITDCCPNLKYVNFSNSISLDGSGFIAVLRGLKELKRIDIINCDSVSRDAIDWARSKGMQVTVASSLPNSQPLGTKKIRLI
What is the function of this protein?
Has a role in substrate recognition in the Skp1-Cullin-1/Cdc53-F-box (SCF) ubiquitin ligase complex.  Required for the maintenance of telomere length and transcriptional silencing at the telomere.  Also required for chromosome segregation.
What are the official names of this protein?
F-box/TPR repeat protein pof3.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.
Protein: YQAO_BACSU
Sequence: MYNPREINIKKDFTIQQKIDPGKVQIIVLDGNQGTAHVLDAPEHGKTVIQTVKGSFARVDHEIGFKVK
What are the official names of this protein?
Uncharacterized protein YqaO.
What is the protein family that this protein belongs to?
To B.subtilis XtrA.
Protein: ENO_THEAC
Sequence: MELPIEEIKVRKVLDSRGNFTVEADVTVPNGFGRTSAPAGASTGETEVIAFSKSGIDASIQFFESKVKRSLIGFNALDQSGFDKLLTDIDGSGNFSNLGGNLATALSMSVAKAAAQSLGIPLYRYVGGIRSTIPRPMGNVIGGGKHARNGTSIQEFLVSAQGSTFLESAYINVLVHRRIGDMLSDKFKDISIGVGDERTWSVNLSDEEAFEILNEAVKEISSEKKVKIYTGVDFAADSLYENGKYVYKHTTKSRDEQIDYAISISKDFGVYYIEDPMYDTDFDGFAEITARIGDRSLIVGDDLYTTNPDRIRKGVEKKSTNAVLIKVNQIGTLSAAREAVAVATFAGMKNIVSHRSGETTDDFLAHLSVAFGSTFVKTGVIGGERVAKLNEIARIEECLTS
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PSAG_ARATH
Sequence: MATSASALLSPTTFSTAISHKNPNSISFHGLRPLRLGGSSSALPKLSTTGRKSSSAVVRAELSPSIVISLSTGLSLFLGRFVFFNFQRENVAKQGLPEQNGKTHFEAGDDRAKEYVSLLKSNDPIGFNIVDVLAWGSIGHIVAYYILATSSNGYDPSFFG
What is the function of this protein?
Not yet known.
What are the official names of this protein?
Photosystem I reaction center subunit V, chloroplastic, PSI-G.
What is the protein family that this protein belongs to?
Belongs to the PsaG/PsaK family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: ATF1_HUMAN
Sequence: MEDSHKSTTSETAPQPGSAVQGAHISHIAQQVSSLSESEESQDSSDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGVSAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMTNSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSNKSV
What is the function of this protein?
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters.  Binds to the Tax-responsive element (TRE) of HTLV-I.  Mediates PKA-induced stimulation of CRE-reporter genes.  Represses the expression of FTH1 and other antioxidant detoxification genes.  Triggers cell proliferation and transformation.
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, Protein TREB36.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ATF subfamily.
Protein: KBRS2_DANRE
Sequence: MGKSCKVVVCGQGSVGKTAVLEQLLYANHVVGSETMETLEDIYIGSVETDRGTREQVRFYDTRGLRDGQEFPRHYFTFADGFVLVYSIDSRESFKRVEALKKEIDRCRDKKEVTIVVVGNKLDLQDQRRVDSSAAQQWARQEKVRLWEISVTDRRTLIEPFVHLASKMTQPQSKSTFPLSRNKNKTSGSLDS
What is the function of this protein?
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation.
What are the official names of this protein?
NF-kappa-B inhibitor-interacting Ras-like protein 2, I-kappa-B-interacting Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_RUEPO
Sequence: MPAFDTPAMMLILWAVIGYGLGSIPFGLILTRAMGMGDLRQIGSGNIGTTNVLRTGNKGAAALTLLLDGGKGAVAVLLARAFAGEDAAQVAALAAFVGHCYPIWLGFKGGKGVATFLGLWLALAWPVGVACCLSWLAGAAVTRISSMGALVAAASSTFWLVLLDQGAGFVLGIVLTLMVFWRHRANIARLKARTEPKIGQKSA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUDC_HAEIN
Sequence: MKILQQDDFGYWLLTQGSNLYLVNNELPFGIAKDIDLEGLQAMQIGEWKNYPLWLVAEQESDEREYVSLSNLLSLPEDEFHILSRGVEINHFLKTHKFCGKCGHKTQQTQDELAVQCIHCGYQTYPVICPSIIVAVRRGHEILLANHKRHYSPNGGIYTTLAGFVEVGETFEQAVQREVFEETGISIKNLRYFGSQPWAFPNSQMVGFLADYESGEITLQESEIHDAQWFSYDQPLPELPPTGTIARKLIHVTLELCKAEHKCD
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: FYV10_YEAST
Sequence: MAEKSIFNEPDVDFHLKLNQQLFHIPYELLSKRIKHTQAVINKETKSLHEHTAALNQIFEHNDVEHDELALAKITEMIRKVDHIERFLNTQIKSYCQILNRIKKRLEFFHELKDIKSQNSGTSHNGNNEGTRTKLIQWYQSYTNILIGDYLTRNNPIKYNSETKDHWNSGVVFLKQSQLDDLIDYDVLLEANRISTSLLHERNLLPLISWINENKKTLTKKSSILEFQARLQEYIELLKVDNYTDAIVCFQRFLLPFVKSNFTDLKLASGLLIFIKYCNDQKPTSSTSSGFDTEEIKSQSLPMKKDRIFQHFFHKSLPRITSKPAVNTTDYDKSSLINLQSGDFERYLNLLDDQRWSVLNDLFLSDFYSMYGISQNDPLLIYLSLGISSLKTRDCLHPSDDENGNQETETATTAEKEVEDLQLFTLHSLKRKNCPVCSETFKPITQALPFAHHIQSQLFENPILLPNGNVYDSKKLKKLAKTLKKQNLISLNPGQIMDPVDMKIFCESDSIKMYPT
What is the function of this protein?
Required for the adaptation to the presence of glucose in the growth medium; mediates the degradation of enzymes involved in gluconeogenesis when cells are shifted to glucose-containing medium (PubMed:12686616, PubMed:22044534).  Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBP1) (PubMed:12686616, PubMed:22044534).  May catalyze ubiquitination of target proteins in complex with RMD5 (Probable).  Required for survival upon exposure to K1 killer toxin (PubMed:12663529).
What are the official names of this protein?
Protein FYV10, Function required for yeast viability protein 10, Glucose-induced degradation protein 9, Probable E3 ubiquitin-protein ligase GID9.
What is the protein family that this protein belongs to?
Belongs to the FYV10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYH_STAAC
Sequence: MIKIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGDSTDVVQKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSVDAEVLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTNPMRILDCKVDRDKEAIKTAPRITDFLNEESKAYYEQVKAYLDDLGIPYIEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTLCGGGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIELDIEENLDLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_MYCVP
Sequence: MKPGIHPDYHPVVFQDANTGKQFLTRSTLTSARTVEWETSEGVREYPLVVVEVTSDSHPFWTGSRRIVDAAGQVEKFRRRYGSRKSGASSD
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: MRAZ_ECOHS
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SECA_SALCH
Sequence: MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELKAKTNEFRARIEKGESVESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKKVNKIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPGNIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTANGQPVLVGTISIEKSEVVSRELTKAGIKHNVLNAKFHANEAGIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALEAPTEEQIAQIKADWQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSDTINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLEMPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEMQRREEAERLAQMQQLSHQDDDAAVAADLAAQTGERKIGRNDPCPCGSGKKYKQCHGRLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MNMA_SHEHH
Sequence: MTSIEPTHLGKKVIVGMSGGVDSSVSAYLLMKQGYQVEGLFMKNWEEDDTDEYCAAADDLKDAQAVCDKLGIKLHTVNFASEYWDNVFEYFLAEYKAGRTPNPDIMCNKEIKFKAFLEFADEILDADYIAMGHYVRRRDIDGTSQMLRGIDGNKDQSYFLYTLGHEQVARSLFPVGELEKSEVREIAKEMGLITHDKKDSTGICFIGERKFTDFLQTFLPAQPGNIETSEGEVIGTHQGLMYHTLGQRKGLGIGGLKNSNEDPWYVVEKDLVRNVLIVGQGGNHPRLMSNGLIANQLHWVDRKGPADGSNITVKTRYRQQDVPCRVTYDSDDILRVIFDEPVAAVTPGQSAVFYDGEICLGGGIIDALIRD
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORN_XYLFT
Sequence: MVAELPVVESDRRLIWIDLEMTGLDTHRDSIIEIATVVTDAQLNVLAEGPEFAISHPLNVLEAMDEWNRNQHRHSGLWQRVLNSEIQHAQAEASTIAFLQQWVKIGASPMCGNSICQDRRFLHRQMPCLERYFHYRNLDVSTLKELAGCWSPSILDGVVKTSSHTALSDIYDSIAELRHYRKSMGTFAGLSVV
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_CLOP1
Sequence: MNKFKLIVTTPERVLISGEVSRVLCKNAVGEFEILAGHQPYLTATVPTVTRIDDENGESKYLFTSTGLMKVQNNEVTFCVNSAEWPEEIDEARAMNAKQRAEERLKNKTDELDEKRAKLALARAMSRLKLKEM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PURT_SYNS9
Sequence: MTAFPRTVMLLGSGELGKEVAIAAQRLGCRVIACDRYANAPAMQVADTAEVFQMTDATALKEVVQRHRPDVVIPEIEALAVEALAELEQDGITVIPTARATAFTMNRDQIRDLASGELGLHTARFAYASNAAELKKVAAPLGWPVVVKPVMSSSGKGQSVVQTPEQLDQAWEAAMANARGTSNQVIVEEFLEFDLEITLLTIRQRNGETLFCPPIGHEQERGDYQCSWQPAQMSDAQLQQAQTMARTVTDNLGGAGLFGVEFFLCGNEVIFSELSPRPHDTGLVTLISQNLSEFELHLRAVLNLPIPQLTTAPAAASRVILADRELKTVAYEGLEQALREAGTQVLLFGKPNARPNRRMGVALARGEDLSEVRAKADRAAACIQVLDGSARR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: PORA_CUCSA
Sequence: MALQAASLVSPALSIPKEGKSSVCLKDSSLFGISFSDHLKSEFSSSTLRCKRELNQQIGAIRAQTTATESPAVNKATPDGKKTLRKGSVVITGASSGLGLATAKALAETGKWHVIMACRDFLKAERAAKSAGITKENYTVMHLDLASLDSVRQFVDNFRQSGRPLDVLVCNAAVYLPTAKEPTFTAEGFELSVGTNHLGHFLLSRLLLEDLNKSSYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLAGGLNGLKSSMIDGGEFDGAKAYKDSKVCNMLTMQEFHKRYHEETGITFASLYPGCIATTGLFREHIPLFRILFPPFQKFITQGYVSEDEAGKRLAQVVSEPSLTKSGVYWSWNKNSASFENQLSQEASDAEKARKVWELSEKLVGLA
What is the function of this protein?
Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
What are the official names of this protein?
Protochlorophyllide reductase, chloroplastic, PCR, NADPH-protochlorophyllide oxidoreductase, POR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YHIT_CHLPN
Sequence: MTVFKQIIDGLIDCEKVFENENFIAIKDRFPQAPVHLLIIPKKPIPRFQDIPGDEMILMAEAGKIVQELAAEFGIADGYRVVINNGAEGGQAVFHLHIHLLGGRPLGAIA
What are the official names of this protein?
HIT-like protein CPn_0488/CP_0266/CPj0488/CpB0508.
Protein: DDL_STAA1
Sequence: MTKENICIVFGGKSAEHEVSILTAQNVLNAIDKDKYHVDIIYITNDGDWRKQNNITAEIKSTDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNGVLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPANLGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMYPKLWENMGLSYPELITKLIELAKERHQDKQKNKYKID
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_TRIV2
Sequence: MTNLLPEMAEIWQQTLNWQPTDSQQARFQQLYELILEGNRQLNLTRITEPQEFWEKHLWDSLRGVAPQQQLISFLPVGASVIDIGTGAGFPGVPVAIIAPNSTMTLVDSTRKKIAFIESILKELGLTNAKTLVSRAEEIGQQPQHREQYDVALIRAVGTASACAEYTLPLLKLGGLAVIYRGTWTEEETTSLENAVRQLGGTVELIDNFTTPLTNSVRHCLYLRKVAKTPANFPRAVGVPTQKPI
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_MPLV
Sequence: MACSTLPKSPKDKIDPRDLLIPLILFLSLKGARSAAPGSSPHQVYNITWEVTNGDRETVWAISGRLYVSGRDPGLTFGIRLRYQNLGPRVPIGPNPVLAD
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
Virion membrane.
Protein: CGLR_LUCCU
Sequence: MELQANLENVLQKVNNFINIDAKRQIYAAHFDNLKNTIFNELRKNEVLAYLFNGFQLGGSYGDNVKVTVPNEYDLVFNIKFPEQPLIIVTADHELPGNVFLDFTRVIHKIAKEKQHEKILQHLKQWLDDENYLKVEKFQWFLRSCFIDVLTKMNFKITFKGRTSSLRYSREGPAHTIKVTESLNFDYSVDFVPGILLNANQCVTSNIVGQWEAIPKPTPTNNHLYKSFRASFYRQEQKIIKNQQQLKNVYRMMKKFRDSKTNMLKMKSYFIKTLFLWKSSRENVSYWSKPLTEIIIDMFKDMEKSLREEKLPFYWDRKLNLYDNYQPRLMREMLNCVESARETLEKAAKELTLPLQKRVFCIFCKLKI
What is the function of this protein?
Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (3',2'-cGAMP) from ATP and GTP and plays a key role in innate immunity (PubMed:34261127).  Synthesizes 3',2'-cGAMP in a two-step reaction through production of the linear intermediate pppA(2'-5')pG (By similarity).  Acts as a key sensor of double-stranded RNA (dsRNA), the presence of dsRNA in the cytoplasm being a danger signal that triggers the immune responses (PubMed:34261127).  Directly binds dsRNA, activating the nucleotidyltransferase activity, leading to synthesis of 3',2'-cGAMP, a second messenger that binds to and activates Sting, thereby triggering the antiviral immune response via activation of the NF-kappa-B transcription factor Rel (Relish) (By similarity).
What are the official names of this protein?
Cyclic GMP-AMP synthase-like receptor, cGLR.
What is the protein family that this protein belongs to?
Belongs to the mab-21 family.
Protein: PSB1A_CARAU
Sequence: MMISAQACGANGRMKDYHYTGPVEHKFSPYAFNGGTVLAVAGEDFALVASDTRLSEGYSIHSRDSPKCYKLTDTTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKSMTSGAIAAMLSTILYGRRFFPYYVYNIIGGLDEEGRGAVYSFDPVGSYQRDTYKAGGSASAMLQPLLDNQIGFKNMENVEQVPLSQEKAVQLVKDVFISAAERDVYTGDALKICIITKEGIREEIVPLRKD
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-1-A, 20S proteasome beta-6 subunit A, B6-A.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: G6PI_MAGMM
Sequence: MSSLTQLPQWQALQTHLEENRSVQMRDLFDQDSQRFSRFSLQQGELLFDYSKNRITAETMARLLDLARAQDVEGWRDRMFAGEAINETEGRAVLHVALRNRSGRPIRVAGEDVMPAINQVLQQMRQFSEAVRSGAWKGQSGQAITDVVNIGIGGSDLGPVMVCEALKPYHQPGLSVHFVSNVDGTHMAETLKGLNAETTLFIVASKTFTTQETLTNAHTARDWLVAQLGEAAVRKHFVALSTNAEAVSAFGIDTDNMFAFWNWVGGRYSLWSAIGLPIAIAVGFEGFMALHDGAYAMDEHFRTAPLASNMPVIKALIGIWNHNFLGAESFAVLPYDQYLHRLAAYLQQADMESNGKYVTRDGARVDYTTGPVLFGEPGTNGQHSFYQLIHQSTRLVPADFIAAAHTHNPVGDHHAKLLSNFFAQTEALMTGKTAAQVRQELEAAGLHGAALEALVPHKVFDGNRPTNSILVRQFTPYTLGQLIALYEHTIHVQGMVWGINPYDQWGVELGKQLAKKILPELTTPGEVHSHDGSTNGLINHYKAWLAE
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_YERPY
Sequence: MKNINPSQTAAWKALQQHFEQMKDVTISSLFAKDDQRFNRFSATFDDQMLVDFSKNRITSETLEKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHIALRNRSNTPIVVDGKDVMPEVNAVLAKMKQFCDRVISGDWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEALKPLNPETTLFLVASKTFTTQETMTNAHSARDWFLSAAGDPAHVAKHFAALSTNAKAVGEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSVGFEHFEQLLSGAHAMDKHFAETPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFPAYFQQGNMESNGKYVDRNGHPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAISHNPLSDHHAKLLSNFFAQTEALAFGKSLEDVEAEFAAAGKTPEQVAHVAPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIYTFDQWGVELGKQLANRILPELADDQEVTSHDSSTNALINRFKNWR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_BACAN
Sequence: MLAKRIIPCLDVKEGRVVKGVNFIGLQDVGDPVEIAALYNDAGADEIVFLDITATHEGRKTIIDVVEKTASKVFIPLTVGGGISSVKDMYNLLRAGADKVSINSAAVRNPKLIEEGAQHFGSQCIVVAIDARKVAEGKWNVYVNGGRVDTGMDAIGWAKRVVMLGAGEILLTSMDADGTKNGYDLRLTEEISKSVSIPVIASGGCGHADHIIEVFQKTTVDAALAASIFHYGEATIGDVKRKLRNANVEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.