PharMolix/UniProtQA huggingface dataset:
Protein: KYNU2_ASPCL
Sequence: MSTTTTSSKPEFPADAATKEYAASLDASDPLAGFREKFIIPSKANIASKKLAKPGLSSEPCIYFCGNSLGIQPKATAKYLEAQLDTWSSIGVSGHFTNVEDSPLREWQNLAEQAAESMSRVVGAAPEEVAAMGTLTMNLHLLLASFYRPTATKHKILMDWKAFPSDHYAIESHIAWHDLDPKESMVLIGPDEGTFEIPTEKILSYIDQHADDAALILLPGIQYYTGQLFDIQKITEYAQSRGLVVGWDLAHAYGNVHLKLHDWNVDFAAWCTYKYGNAGPGAMAGLFVHERHGRVDYREGEDSPKFRHRLTGWYGGDKSVRFKMDNNFKPIPGAGGYQISNPSAIDLASLCAALSVFDETSMAELRRKSVLMTAYLEHLLLKDTTDESRLFDIITPSEPAARGAQLSLLLRPGLLHKVAQRLQEAGIICDKREPGVVRVAPVPLYNTFTEVWTFVEQLKAALEE
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase 2, Biosynthesis of nicotinic acid protein 5-2, L-kynurenine hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_LIMRD
Sequence: MNFLSAVLTILSSFLITFLLMPSLIKYFRAKKEGQQIRKEGPTWHAKKAGTPTMGGLLFIFSAVVTILWVAAWQGLITNTLWALLFVLVVYGLIGMWDDSIKIFHHQNEGFKPWQKALCQVLAAMVFTVIYQHEGFQMGFGTTQIGWLYGLFIIFWIVGFSNAVNLTDGLDGLVSGLSIISFAAYLIIALVNLNQPGYPEIALFCLAMIGTLLGFFPYNHKPAKIFMGDMGSLAIGASLAAVSLLLHHEWSLLVIGIVYVCETASVILQVASFKTTGKRIFKMTPIHHHFEMSGWSEWKIDIVFWLVGLVAAIIAVTTILLVG
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR9_SHEDO
Sequence: MNTVRPIRRALLSVSDKTGILEFAQALHAHGVELLSTGGTARLLAEHGLPVIEASDHTGHPEIMDGRVKTLHPKIHGGILARRGQDEAVMAENNILPIDLVVVNLYPFASTVANPDCTLADAVENIDIGGPTMVRAAAKNHQDVTIVVNASDYARVLAEMKTNQGSTTLKIRFELAVAAFEHTAAYDGMIANYFGNLVAMDADTSDEQQALHQESSFPRTFNSQFIKKQDLRYGENSHQKAAFYVDPQIDEASVASAIQLQGKALSYNNIADTDAALECVKEFDGPACVIVKHANPCGVALGKDLLDAYNRAYQTDPTSAFGGIIAFNGELDAATASAIVERQFVEVIIAPSVSQAARDIVAAKANVRLLECGKWETKTTSLDYKRVNGGLLVQDRDQGMVGLADIKVVSKRQPTEAELKDLLFCWKVAKFVKSNAIVYAKEGMTIGVGAGQMSRVYSAKIAGIKASDEGLVVENSVMASDAFFPFRDGIDAAAAAGISCIIQPGGSIRDEEIIKAADEHGMAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: ATPF_BACP2
Sequence: MSQLPVVLGAGLNTGDIIFQLIAMLILLALLKKFALKPLLGIMKQREDYIGNEISSAEQKHVQAEKLLEEQRVLLKEAREESHTLIENAKKIGEKQKEEIIQAARQESERLKDSARTEIVKEKEQAVAALREQVASLSVLIASKVIERELDEQAQEKLIQEYLKEAGESR
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: WNT11_CHICK
Sequence: MKPSPQFFLAAFLSLILQTGICYGIKWIALSKTPSSLALNQTQHCKQLEGLVVSQVQLCRSNLELMQTIIQAAREVIKTCRKTFSDMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHTIARACTTGDLPGCSCGPIPGETPGPGYRWGGCADNLNYGLIMGSKFSDAPMKMKKSGSQANKLMHLHNSEVGRQVLKASLEMKCKCHGVSGSCSIKTCWKGLQELRDIALDLKNKYLSATKVVHRPMGTRKYLVPKDIDIRPVKETELIYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYMDKVVERCHCKYHWCCYVTCKKCERTVERYVCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  May play a role in the formation of dermal structure, both limb and feather buds.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-11.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: METE_ACTPJ
Sequence: MTTLHILGFPRVGAKRELKFAQERYWRKELAEQDLLDLAKALREKNWLHQAQADADFVTVGDFTFYDHILDLQVATGAIPARFGFDSQTLSLDQYFQLARGNKEQFAIEMTKWFDTNYHYLVPEFQKNTTFKANSTHYVNQIREAKAAGHQVKPVIVGPLTFLWLGKEKGEAFNRFDLLKQLVPIYFEILTALAAEGVEWIQIDEPALALDLPQEWLAAYQDVYAQLAKVNAKLLLATYFGSVAEHAALLKALPVDGLHLDLVRAPEQLSAFEDYPKVLSAGVIDGRNIWRANLNRVLDVLEPLKAKFNQRLWIAPSCSLLHTPYDLAVETQLQQNNPELYRWLAFTLQKVAELQVLKQALNAGRSAVAEQLNDSQTAADARANSNVIHKAEIAQRLANLPANADKRQSPFAERIKLQNKWLNLPLLPTTNIGSFPQTLEIRHARAAFKKGELSLADYEAAMKKEIEFVVRKQEELDLDVLVHGEAERNDMVEYFGELLDGFAFTKFGWVQSYGSRCVKPPVIYGDVTRPEPMTVRWSQYAQSLTDKVMKGMLTGPVTILQWSFVRNDIPRSTVCKQIGVALSDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLQWAGEAFRLSYMGVKDDTQIHTHMCYSEFNDILPAIAGLDADVITIETSRSDMELLTAFADFKYPNDIGPGVYDIHSPRVPTAGEIEHLLRKALKVIPKERLWVNPDCGLKTRGWKETIEQLQVMVEVTKKLRAELAE
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: MDH_CUPPJ
Sequence: MAKAPMRVAVTGAAGQIGYSLLFRIANGDMLGKDQPVILQLLDLPQAQAAVKGVVMELEDCAFPLLAGVVITDDPKVAFKDADVALLVGARPRSKGMERKDLLEANAQIFTVQGKALDEVASRNVKVLVVGNPANTNAYIAMKSAPSLPRENFTAMLRLDHNRALSQIAAKTGKPVASIEKMFVWGNHSPTMYADYRYATVDGKSVKDMINDPVWNNDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHVHDWVLGTNGKVVTMGIPSNGEYGIPADTMFGYPVTCANGKYEIVKGLEIDAYSQEKINITLNELEEEKAGVQHLLG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: TBB_ASPPA
Sequence: MREIVYLQTGQCGNQIGAAFWQTISGEHGLDGSGVYNGSSDLQLERMNVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVVDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVMPSPKVSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICMRTLKLSNPSYGDLNHLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVSMKEVEDQMRNIQSKNQTYFVEWIPNNIQTALCSIPPRGLKMSSTFIGNSTSIQELFKRVGDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASISEGEEEYLEEEEPLEHEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YDBJ_BACSU
Sequence: MAEPILHIEGLDKKIGSKQILKQISMDVMEGEIIGLLGPNGSGKTTLIRIIVGLLKQNSGSVTISGFQHDTEFEKAMEAVGAIVENPEFYPYLTGWENLKHFANMHKKIADERLDEVVERVGLTSAIHDKVKTYSLGMRQRLGIAQAILHRPKLLILDEPTNGLDPAGMKDFRDHIKELAEMEGTAVLFATHLLREVEDLCDRVIIIQKGEIKAEVSLQGTDQTTEKAIIEVQPQEKALNWLTGNQYQAESQDGTIVVEVAKENIPELNRSLVGQDLNVFSITPYTQSLEDEFIKATTAHQEEGEELV
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YdbJ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: NRX2A_RAT
Sequence: MALGSRWRPPPQLPPLLLLLALVAGVRGLEFGGGPGQWARYARWAGAASTGELSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGAAADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEGEHPMEGPAHLTLNSPVGSLLFSEGGAGRGGAGDVHQPTKGKEEFVATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGAGVGSHSSSQRADYFAMELLDGYLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVNSRSTPFLATGESEVLDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGICREGWNRFVCDCIGTGFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSAAGKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGAHTRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTMRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPSSGGPCQAERDDSDCEEPVEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLLAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGVPTAFEPRRPPPLRPGVTSVPGFPRLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV
What is the function of this protein?
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.  May mediate intracellular signaling.
What are the official names of this protein?
Neurexin-2, Neurexin II-alpha, Neurexin-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SECA_COLP3
Sequence: MFGNLLTKMFGSRNDRLLKQMSKEVTKINALEPVLEALSDEELKAKTTEFKERFTQGETVEQLLVEAFAVVREASKRVFGMRHFDVQMIGGMVLNEGKIAEMRTGEGKTLTATLPSYLNALTDKGVHVITVNDYLATRDADWSRPLFEFLGLTVGCNVAGMTTQDKQAAYQSDITYGTNNEFGFDYLRDNMVFSPQERSQKPLHFAIIDEVDSILIDEARTPLIISGQAEDSSALYKIINTLVPTLEQQEEEDKEGEESTGDFTIDEKAKQVYLTERGQIHIEEIMVEKELLTAGDTLFSAANITLLHHVMAALRAHKLFQKDVDYIVKDDEIVIVDEHTGRTMEGRRWSEGLHQAVEAKEGVNIQNENQTLASITFQNYFRIYEKLSGMTGTADTEAFEFNHIYGLETVIIPTNQPMVRKDLSDLIYLTTEEKFEAILADIQDCVKRGQPVLVGTIAIETSEFLSDFLKKAKIKHKVLNAKFHQQEAEIVADAGKENAVTIATNMAGRGTDIVLGGNLDATIAKLTNPSEDDIAKAKAQWKIDHERVLELGGLHIVATERHESRRIDNQLRGRSGRQGDEGSTRFYLSMEDSLMRIFASERISNMMRKLGMEKGEAIEHPWVTRSIENAQRKVEGRNFDMRKQLLEYDDVANDQRGVIYEQRNELLDNEEIGSVVEAIRSDVINGVIDQHIPRQSLDEMWDIEGLEEQLKGEYATELTIAKWLEDDSKLHEESLREKIITEFEQAYKDKEEAVGVDVLRQFEKAVMLQSLDSHWKEHLSAMDHLRQGIGLRAHAQKNPKQEFKRESFELFTEMLDNLKYDVVGILSKVQIRAESDVEAVEEQHRKSEEVPMDFQHQSASSPSEQAQTPRVGRNEPCPCGSGKKYKQCHGKLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: SYGB_HAEAE
Sequence: EFTDTQGVMGMHYARHDGEDEEVAVALNEQYMPRFAGDELPKSLVASAVALADKFDTLTGIFGIGQAPKGSADPFALRRAALGALRIIVEKNLPLDLEDLVKKSAALFGDKLANQNVVADVVDFMLGRFRAWYQDEGIAVDVIQAVLARRPTRPADFDARVRAVSHFRTLDSAEALAAANKRVSNILAKADAAIGEINLTVCVEQAEKALAEAVLALRTEVQPLIEQGDYTTVLDKLANLRAPVDSFFDNVMVNAEDPALRQNRLAILNTLQGLFLQVADISVLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_ECOUT
Sequence: MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALNTLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEYLEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLNMVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: TX604_LYCSI
Sequence: MKLLFFTALVLVVISLIEVEAENERACIPLEKECTKTPGNCCSGLKCDCYRRFEQGVAKGIQCWCIEKDVTYKGV
What are the official names of this protein?
U6-lycotoxin-Ls1d, Toxin-like structure LSTX-F4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 06 (U6-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GSPN_KLEPN
Sequence: MKNRLTIGLLLAAIYLFWLLLSAPARLLALTLSDDARLAQTSGTLWQGEAHQASWRGVELAYLRWEFGFSTWLPGWHIRFNDPSGLRGQAWLHGLNEFVVREGRLVIPARLISQRLALGMPLEARGQLALTLPEASFNANGCRRIAASAVQWQDAALSSPAGLLELAQVNGKLSCTPAGALAVALTQDSHQLSLTGQGVLTPDGRYTFNGTLQPRQAAPALLTLLVAQNGRKDEQGRIPWRWQGEWLSEEKK
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity).  Required for the translocation of pullulanase.
What are the official names of this protein?
Type II secretion system protein N, T2SS protein N, General secretion pathway protein N, Pullulanase secretion protein PulN.
What is the protein family that this protein belongs to?
Belongs to the GSP N family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: PURA_PROMA
Sequence: MANVVVIGAQWGDEGKGKITDLLSRSADVVVRYQGGVNAGHTIVVDEKVLKLHLIPSGILYPETICLIGSGTVVDPKVMLKEIKMLKDNDIDISGLQLASTAHVTMPYHCVIDAAMEERRGLKKIGTTGRGIGPTYADKSQRNGIRVIDLLDERKLREALEIPLAEKNELLEKIYGKEAIDKEKIIEEYLEFGRLIKPHVVDCTRIIHKASRNKKNILFEGAQGTLLDLDHGTYPFVTSSNPVSGGACIGAGVGPTLIDRVIGVAKAYTTRVGEGPFPTELKGKINDQLCDRGGEYGTTTGRRRRCGWFDGVIGKYAVEVNGLDCLAITKLDVLDELEEIKVCTSYELNGEKIDYFPSSAEDFGKCTPIFKTLPGWKSSTANCRHLEDLPPPAMAYLRFLAELMEVPIAIVSLGASRDQTIVVEDPIHGPKRALLSS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_YERPG
Sequence: MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: HEM3_GEOSM
Sequence: MALKELRIGTRASQLALWQANWVKSELEKRYPDMTVTLTKIKTIGDKILDVPLAQVGGKGLFVKEIEEAMLRGEIDIAVHSMKDVPTEFPEGLGLYCITEREDPRDAVISNNVKFADLPQGARIGTSALRRQAQLLKVRPDLEMVIIRGNVQTRMDKLKTEGLDAVILAAAGLNRLGFADQITELLPTDLSLPAIGQGALGIECNLSNQDVKDAISFFNHPDTSRAVRAERALLWRCEGGCQVPIAAFGEVTGDELKLTGFIASVDGKVSVKGVVTGPADDCEKLGVKLAEQLLSEGGHAILAEVYQREVSREKEIPV
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: YEHZ_ECOLI
Sequence: MPLLKLWAGSLVMLAAVSLPLQAASPVKVGSKIDTEGALLGNIILQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYPEYTGNGAFFFKDENDAAWKNAQQGYEKVKKLDSEHNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLSRYLQEGGTFKLAASAEFIERADALPAFEKAYGFKLGQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMAYGTDGPVAALGLQTLSDPQGVQPIYAPAPVVRESVLREYPQMAQWLQPVFASLDAKTLQQLNASIAVEGLDAKKVAADYLKQKGWTK
What is the function of this protein?
Part of an ABC transporter complex involved in low-affinity glycine betaine uptake.  Binds glycine betaine with low affinity.
What are the official names of this protein?
Glycine betaine-binding protein YehZ.
What is the protein family that this protein belongs to?
Belongs to the OsmX family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ICP46_IIV6
Sequence: MDSKQTKTMNNIVDQVNCLSISSPSKDLEMLNLIEENVTEDPMKHGIRKSHTMEVNGKTLELFCSDNPPQTPLEHQVRGVVFYGSEMILQGFPYSNEQIITEKSTEEEISFLYENNDWTITEAIEGTLIRIFYFNDKWIITTHRKLDAFKSKWGSEKSFGDIFKEAVMIKTKDPQINNDIDVNTLCEKLGLNKHRQYTFLITATDKTRFVCPSTPIPIVYLYAITEKINNKTTIISENDSEMKKWNDWKQESLHLKAPEAIQFVQNLSFPFRCQGLLFFNSKTFESYKLVNKTYQEYFDVRGNIPSVPFAYLHILGNKNKIQMFKQMISEKDIETIEKYEKTIQELIVELHNLYLKRYVEKDTEMKTDKTKHKFLLELHEWFKNQREKCVSTGAIPKIRVTQNVVSKILLESDPPVINRLIKEKIHPSSPTASLSSLSPPSSNNNSPIRSPIRM
What are the official names of this protein?
Immediate-early protein ICP-46 homolog.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 393L family.
Protein: RL35_NATTJ
Sequence: MPKMKTHKGAAKRFKKTGKGKIKRRKAFKSHILTKKTPKRKRNLRKPTVMKNKAEEKRIKRLLP
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ADHX_OCTVU
Sequence: TDATGKPIKCMAAIAWEAKKPLSIEEVEVAPPKSGEVRIKILHSGVCHTDAYTLEGIDPEGIFPVILGHEGAGIVESIGEGVTSVKPGDTVIPLYVPQCYECKFCLNPKTNLCQKIRVTQGKGVMPDGTTRFTCKGKEVFHFMGCSTFSEFTVVAEISIAKVNPKAALDKVCLLGCGISTGYGAALNTAAVEKGSNCAVWGLGAVGLAVAMGCKAAGAARIIGIDINESKFEIGKKFGITEFVNPKKFCKSVQKVLGEMTDVGVDFTFECIGNVGVMRAALESCHKGWGTSVIVGVAAHGEEISTRPFQLVTGRVWKGTAFGGFKSRDSVPKLVDDYMNKKLLLDEFVSHKLSFKKINEAFDLMHKGESIRAVLDIPE
What is the function of this protein?
Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.
What are the official names of this protein?
Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH, S-(hydroxymethyl)glutathione dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_KINRD
Sequence: MPEGDGVPRETPSPSVVPESPVEVPVEAVARVFGDRADRAATYRELLATAGVERGLIGPREVPRLWDRHLLNCAYLGEVIDQGSSVIDLGSGAGLPGIPLALARPDLQIRLVEPLERRYTFLREAITELGLRDQVAVARGRAEDVRGEFSASVVTARAVAPLKTLYGWALPLVVTGGHLVAIKGRSASDEIAAAGETLRQMGVTAAPEVLSVGPDDGTGTTVVRVARGHGPLRAATAPAPPGAAKRRPGKGNRR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_JAEHI
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTIFNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GLPK_ECO5E
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: CARTF_BOVIN
Sequence: MEQSVDSLKVNHNDSEESKTDSQHLTYMDSSEPSFGQDGSPRVLPVTTPEEDGSLTSQNIPGPLTQAQILSAEQFHLVDQNGQPVQYELQSLGDSNAQMMIVASPSENGQVLRVIPSPQTGMTQVIIPQGPLVDENSPQDVSEEKPSDRNLPAVRVDALADSNSSYVLHPQASLTLPKKTVTRILEEPLLAPLQPLSSNTPIWACRLRSCEKIGDSYRGYCVSETELESVLTFHKQQTQSVWGTRQSPSPAKPATRLMWKSQYVPYDGIPFVNAGSRAVVMECQYGPRRKGFQLKKIGELENRSCQLYKATCPARIYIKKVQKFPDYRVPTDPKIDRKIIRMEQEKAFNLLKKNLVDAGGVLRWYVQLPTQQAHQYHELETPCLPLSSSSFPISSLEEEEAAIRDENCTLPSRLHPQVAHKIQELVSQGIEQVYAVRKQLRKFVERELFKPDEVPERHNLSFFPTVNDIRNHIHEVQKSLRNGDNICNSEIIPATLQWTTDSGNILRETVTVTLAEGNSQGESVSSKLETNQTRNSLSPEPAQLLSSLSSFQPKIFTHLQGLQLQPRFTSDGSPALISVNNHPSSSPSRLLDSVRSVVMNNNSLLLGQTHCLQTDTPLTPNSSISSTMSNLPGPDQNLVAVDQLVEVEDVEDTETLEGNVHRILLGNVQTIPIQIIDNPPVLSNFGSILKEPIFDCFGGPIKI
What is the function of this protein?
Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription.  Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence (By similarity).
What are the official names of this protein?
Calcium-responsive transcription factor, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: HPIP_RAT
Sequence: MILQQPLERGPPGRDPRATTGVTLGLDTREPLHKHFLSEENMATHFSRLSLHNDHPYCSPPVTFPEALPPLRSPCPELLLWRYPGSLIPEALRLLRLGDNPSPYYSASPAGEIMEL
What is the function of this protein?
Regulates HCFC1 activity by modulating its subcellular localization.  Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm.  HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus (By similarity).
What are the official names of this protein?
Host cell factor C1 regulator 1, HCF-1 beta-propeller-interacting protein, Inhibitor of four 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner.