PharMolix/UniProtQA huggingface dataset:
Protein: Y5654_DICDI
Sequence: MLSRATRLLSTKNVVVNSIVKHTTIRSFASHGGGEAGGAYPTEPEAGTQMITRRVEFGDAVYSYKHGNFIVDPIQIRELAEEQQQQQHHVHGPGCSHGHHHDSHANDGHHDEHHDEHHDHVNPDDVEDEFPRGYFLNTPPSVPYPMNPYYLTALCLLPIIGSLFSIRYFDNKSENDYELFRSEYLEANPALKQKYYDITHKYPLSH
What are the official names of this protein?
Uncharacterized transmembrane protein DDB_G0283731.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RUTF_SHIDS
Sequence: MSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: NCA11_XENLA
Sequence: MLHIKDLIWTLYFIGTAVALEVNIVPDQGEISLGESKFFLCQVSGEATDISWYSPTGEKLVTQQQISVVRSDDYTSTLTIYNASSQDAGIYKCVASNEAEGESEGTVNLKIYQKLTFKNAPTPQEFKEGEDAVIICDVSSSIPSIITWRHKGKDVIFKKDVRFVVLANNYLQIRGIKKTDEGTYRCEGRILARGEINYKDIQVIVNVPPTIQARQLRVNATANMAESVVLSCDADGFPDPEISWLKKGEPIEDGEEKISFNEDQSEMTIHHVEKDDEAEYSCIANNQAGEAEATILLKVYAKPKITYVENKTAVELDEITLTCEASGDPIPSITWRTAVRNISSEATTLDGHIVVKEHIRMSALTLKDIQYTDAGEYFCIASNPIGVDMQAMYFEVQYAPKIRGPVVVYTWEGNPVNITCEVFAHPRAAVTWFRDGQLLPSSNFSNIKIYSGPTSSSLEVNPDSENDFGNYNCTAINTIGHEFSEFILVQADTPSSPAIRKVEPYSSTVMIVFDEPDSTGGVPILKYKAEWRVIGHEKWHTKYYDAKEVNAESIITVMGLKPETSYMVKLSAMNGKGLGDSTPSQEFTTQPVREPSAPKLVGHLSEDGNSIKVDILKQDDGGSPIRHYLVNYRALNALEWKPEMRVPSNSHHVMLKALEWNVDYEVIVVAENQQGKSKPALLSFRTTAKPTATTATASAGTGLGTGAIVGILIVIFVLLLVVVDVTCFFLNKCGLLMCIAVNFCGKAGPGAKGKDIEEGKAAFSKDESKEPIVEVRTEEERTPNHDGSNQIEPNETTPLTEPEHPAAVEDMLPSVTTVTTNSDTITETFATAQNSPTSETTTLTSSTAPPPTTAPDSNTIQSIQATPSKAEAPTTSSPPPTSSPKVAPLVDLSDTPTNNPSKVVANQAGPLNPSAATSAAEPPTVIIKPVTTVPPNAASPPPTPEPKQVKQEQSGTKSPEKEEAQPSTVKNPTEATKDESASLSNTKPLQDEDFQIDGGTFKTPEIDLAKDVFAALGTATPTAVASGKASELVSSTADTSVPLDSAKTEKTQVEEKSKPEEIDVKGTPAEVKTVPNEATQTNANESKA
What is the function of this protein?
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
What are the official names of this protein?
Neural cell adhesion molecule 1-A, N-CAM-1-A, NCAM-1-A.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ARGR_CORGL
Sequence: MSLGSTPSTPENLNPVTRTARQALILQILDKQKVTSQVQLSELLLDEGIDITQATLSRDLDELGARKVRPDGGRAYYAVGPVDSIAREDLRGPSEKLRRMLDELLVSTDHSGNIAMLRTPPGAAQYLASFIDRVGLKEVVGTIAGDDTVFVLARDPLTGKELGELLSGRTT
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_MAGMM
Sequence: MALKNFKPTSDGKRHQVAINYSELSNEGPERSLLAPLKRTGGRNNNGRMTVRHQGGGHKRRYRIIDFKRNKFDVPAKVARIEYDPNRTAFIALLHYADGEKSYILAPQRLQVGDTVVSAKTLDNVDVKPGNCMPLRVMPIGTIIHNVELKPGKGGQVARSAGNYIQLMGKEGKYAQLKMPSGEMRLVLLECMATVGMVSNPDNSNTKIGKAGRTRWMGKRPSVRGVVMNPVDHPHGGGEGRTSGGRHPVTPWGVPTKGKKTRSKTKASDRLIMRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NCB5R_PICST
Sequence: MADTEPSPLFVFSTIAIIISTFVIFYFVQQSKKNTPVLKPDTFQKFPLIEKTRVSHNSSVYRFGLPKSTDRLGLPIGQHISIGATIGGKEVVRSYTPISTDDELGYFDLLIKTYENGNISKHVDSKKVGEYVEIRGPKGFFTYTPNMVKSFGMIAGGTGIAPMYQIITAILRNPADKTKISLIYANVTESDILLKSELDKWAEEHPDNFSVHYVLNEAPENWKGSVGFVTPEIIDSKLPKASDDSNLLLCGPPPMISAMKKAAVGLGFAKAKPVSKLGDQVFVF
What is the function of this protein?
NADH-dependent reductase for DPH3 and cytochrome b5.  Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.  By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex.  The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.
What are the official names of this protein?
NADH-cytochrome b5 reductase 1, Microsomal cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: FABR_SALTI
Sequence: MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDIGAEQRRQLEERLVLQLRMIAKGAYYWYRREQEKIAHHSE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_LISIN
Sequence: MVYLQKQDKEVFDAIKLELGRQRANIELIASENFVSEQVMEAMGSVLTNKYAEGYPGKRYYGGCEFVDIVEDLARDRAKKLFGAEYANVQPHSGAQANMAVYHTVLEPGDTVLGMNLSHGGHLTHGSPVNFSGVLYNFVEYGVREDTKEIDYEIVREAALKHKPKMIVAGASAYPRKIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPYADFTTTTTHKTLRGPRGGMILAKAEWEQKLNKSIFPGIQGGPLMHVIAAKAVAFGEALQPEFTAYCEQIIRNSKKLAETLQANDVAVLTGGSDNHLLLIDLKPLGLTGKAAEKVLDEVGITVNKNTIPFETESPFVTSGIRVGVAAVTTRGFDEVAIEKVGVLISEVLHNLENEEVLADVKARVANLTNEYPLYPSL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRG9_CHAGB
Sequence: MSISYVARIINGNSEVGILDQVREPTLKIFVRTIAQIHVPLRTTTPRATQYRALSTQPNRACTQQTSSILATTPRALHTSCARDRDWQAPKPFKRRGGGRSVQNNPLASSHASEPVANDPFRHLSQNDYARPTARPQAYRSKTGDSGGREQRYKPAGGARKPRRPNPESNTQGGNWAEPKTKEPWRIQKEALAKKFPEGWKPRKKLSPDALVGIRMLHQQFPDEYTTETLAQKFEVSPEAIRRILKAKWVADPETEVERQARWHNRGKQVWTKWAALGKKPPRKWRAEGIVRDPIWNEPRGPNHKDKAARAEAQRREAQRRLASGMMG
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MTNB_YEAST
Sequence: MSSQDVLIHSDDPCHPANLICTLCKQFFHNNWCTGTGGGISIKDPNTNYYYLAPSGVQKEKMIPEDLFVMDAQTLEYLRSPKLYKPSACTPLFLACYQKKNAGAIIHTHSQNAVICSLLFGDEFRIANIEQIKAIPSGKVDPVTKKPMALSFFDTLKIPIIENMAHEDELIDDLHKTFKDYPDTCAVIVRRHGIFVWGPTIDKAKIFNEAIDYLMELAIKMYQMGIPPDCGIGEEKKHLKMASP
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: T161A_DANRE
Sequence: MALMGVQLVVSLLAVSIMQRMAPHLSFARWLLCNGSLLKFRHPSEGELCALAGKQIPKTSRRDRRQNGHGESKPLTVPKDIDLHLESTPVNVMDALVLRFFVEYQWLIDFAVYATGIYLFTEGYYSVVDASKEVNIASIWCVLTVLFCLRTLYLLMSHYFLSEEGGERSVCLAFGFLSLLIAMLVLVVREDYLEFGLEPGFTSLFDNFEVFARKQGYEWSVPFTKLSVKLGLAVICAFIGALLAFPGLRLAQTHLDAVQMNADRPMIQILLHMSFLSPLVIIVMWIKPIARDFLGNAPMGKTSVTLLSSSAFSSVRLWTIVVLCVLRLLLTRYHLQAYLNLAQKWVEQMKKEAGRIAAIDIQRKVTRIFCYLTVVTLQYLIPILLVLFSTLALKSLGDFSWGLGAETPGVTPAPIIPSSTPPPVPGPEDDEDMEDMEEDIQATVAHLTELFSALRALLTPIFFRGIFAFLTWWVAACQLISSLFGIYFHQYLMHN
What is the function of this protein?
May play a role in protection against oxidative stress.
What are the official names of this protein?
Transmembrane protein 161A.
What is the protein family that this protein belongs to?
Belongs to the TMEM161 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GATA_CLOB6
Sequence: MDLTKLTAHELKDILSNKEVKAEEITRAFLDRINLVDNKLGAYLYVSEEEAIKKAKEIDGKIEKNEELKALSGIPVGIKDNINVKGMQNTCASKILQGYTSPYDAHVTEKIKKEEGIILGKLNMDEFAMGSSTENSAFKLAKNPWDLERVPGGSSGGSAVAVAGCEATLSLGTDTGGSVRQPASFCGIVGLKPTYGRISRSGVVAFGSTLDQVGPMGKDVEDCALLTSAIAGLDKKDFTTADKEVPDYKKSLTKDIKGKKIGIPKEFFGEGLDEKVRKSVEEAIKVLEENGAEVKPCSLPLMDYALSAYYIISSAEASSNLARFDGIRYGYRSKNFKDAQDIYLKSRSEGFGDEVKRRIMLGTYVLSAGYYDAYYKKALKVRKLIKDDFQRVFKDFDAIVSPTSPTTAFKVGEKKDDVMSMYLSDIYTVPISVAGVPAISLPCGMIDGLPVGLQIISDYFKENVLFNLAYSYEQSVDFYKMRADF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: CLIT4_CLINE
Sequence: MASLEDGTYRLRAVTTSNPDPGVGGEYATVEGARQPVKAEPSTPPFFERQIWQVTRNADGQYTIKYQGLNAPFEYGFSYDQLEQNAPVIAGDPKEYILQLVPSTTDVYIIRAPIQRVGVDVEVGVQGNNLVYKFFPVDGSGGDRPAWRFTRE
What is the function of this protein?
Binds and inhibits cysteine proteinases.  Inhibits most strongly papain and cathepsin L, more weakly bromelain and cathepsin B while it is completely ineffective against cathepsin H.
What are the official names of this protein?
Clitocypin-4/-3, Cysteine protease inhibitor clt4/clt3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I48 family.
What are the subcellular locations of this protein?
Note=Not secreted.
Protein: G6PI_BACVZ
Sequence: MTHVRFDYSRALPFFNEHELTYARDFVKTAHHNIHEKTGAGSDFLGWVDLPENYDKEEFARIKKSAEKIKSDSDVLLVVGIGGSYLGARAAIEALNHSFYNVLPKDKRKNPQVIFIGNNISSTYMKDVMDLLEDADFSINVISKSGTTTEPAIAFRIFRKLLEEKYGKEEAKARIYATTDKERGALKTLSNEEGFESFVIPDDVGGRFSVLTAVGLLPIAVSGADIDEMMKGALDASKDFSSSELEENAAYQYAVVRNVLYNKGRTIEMLINYEPALQYFAEWWKQLFGESEGKDEKGIYPSSANFSTDLHSLGQYVQEGRRDLFETVLNVEKPKHELTIEEAENDLDGLNYLAGKTVDFVNKKAFEGTMLAHTDGKVPNLIVNIPELNAYTFGYLVYFFEKAVAMSGYLLGVNPFDQPGVEAYKVNMFALLGKPGFEEKKAELEKRLEK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_ECOUT
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNESRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFDAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGSTIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ4_PENRW
Sequence: MSVLGRRGAIELRALTASSNLSASTLRPFSVLNRPPPNYPGHVPLTTIERGALALGSAIGSLINPRRADLIAALGEATATPFFIYRLRDAMLSDPTGRRILRDRPRITSETLNMTHLRTLPENSVGRTYAKWLDREGVSPDTRDNVQYIDNEECAYVMQRYRECHDFYHAVTGLPIFVEGELALKALEFLNTLLPMTGLSLFAFVRMKPAEKERFLTLHLPWAIRSGLGSKELINVYWEEVLEKDVDELRAELNIERPPDLREIRKMIRQQQKREKERQQQASN
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein coq4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: NHAA2_CAMJD
Sequence: MQMIKKMALSETFPGILLIFFTFLALLCKNSSLSVIYTDFFHANFTVGFVHFQISKSLDLWINDGLIAIFFLCIGLELKYEILRGQLKNIRAVSLPIFGALGGMITPALIFAAINYSYDFAMKGWAIPTATDIAFAVGILMLLGNKIPTSLKLFLLSLAIFDDLGAIVIIALFYTDQLSALAIIICLFCIFALLLLNYYHITHLSLYVLVGVVLWIAMLKSGVHATLAGVIISLFIPLDTKNKKPYLHEVLKDLNPWVVYFILPLFAFANAGIDIRDMHLGSVFSPVSLGIILGLFLGKQLGVFIFCFIAIKLKLAKLPENIKYGKFYGICILTGIGFTMSLFIDGLAYKNSDIFEHADKLAILIASFLSAIVGFIYLKIVK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LSPA_MYCLE
Sequence: MMGRVPDGPTGLAALVPSVEEAQAMLPPRRLRLLLSIAAVVLTLDIVTKVLAVKFLLPGKSVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVIGIFWMGRRLVSSWWALGLGMILGGAMGNLVDRFFRAPAPLRGHVVDFLSIGWWPVFNVADPSVVVGAILLVVLSIFGFDFDTVGRRKAEFDIAGQRKAEQR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NAGK_ECOLC
Sequence: MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVCELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRLPVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQGDEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITAQLADRLPRHLLPVARVPRIERARHGDAGGMRGAAFLHLTD
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: PSBA_PROMP
Sequence: MTTIQQQRTSLLKGWPQFCEWVTSTNNRIYVGWFGVLMIPCLLAAAACFIVAFIAAPPVDIDGIREPVAGSFLYGNNIISGAVVPSSNAIGLHFYPIWEAATVDEWLYNGGPYQLVIFHFLIGISAYMGRQWELSYRLGMRPWICVAYSAPVSAAFAVFLVYPFGQGSFSDGMPLGISGTFNFMFVFQAEHNILMHPFHMAGVAGMFGGSLFSAMHGSLVTSSLIRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAVFPVVCVWLTSMGICTMAFNLNGFNFNQSVVDANGKIVPTWGDVLNRANLGMEVMHERNAHNFPLDLAAAESTTVALTAPAIG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RECU_LISW6
Sequence: MAIGYPNGKKYAASHEGIPQKKRKAPVTYGKRGMSLEDDLNDTIAYYLAQDIAVIHKKPTPVQIVSVDYPKRSSAKIKEAYFKTPSTTDYNGVYKGKYIDFEAKETQNTTSFPLSNFHDHQMIHMANVLKQDGIVFVIIAFQKIGETYFIPFEKFYPFWQRMQSGGRKSVTIAEIQDVSDQIPYGLNPRLDFLKSIEKLYF
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKTB_ANEVI
Sequence: MVFLLCFFLVADVSYGINKDCLLPKVVGFCRARFPRYYYNSSSRRCEKFIYGGCGGNANNFSSYYECHIKCFGPRAIIFPEDSPKEN
What is the function of this protein?
Kunitz peptide that directly activates neuronal GIRK1/2 (KCNJ3/KCNJ6) channels (EC(50)=80. 9 uM) resulting in larger K+ currents.  This activation is independent from Gi/o protein activity, and has only a minor effect on Kv1. 6/KCNA6 channels (13. 5% inhibition at 1 uM) (PubMed:35200669).  Serine protease inhibitor that inhibits both tissue and plasma kallikreins (By similarity).  Has hemolytic activity (By similarity).
What are the official names of this protein?
U-actitoxin-Avd3n, U-AITX-Avd3n, AsKC11.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: MTNN_MYCTU
Sequence: MAVTVGVICAIPQELAYLRGVLVDAKRQQVAQILFDSGQLDAHRVVLAAAGMGKVNTGLTATLLADRFGCRTIVFTGVAGGLDPELCIGDIVIADRVVQHDFGLLTDERLRPYQPGHIPFIEPTERLGYPVDPAVIDRVKHRLDGFTLAPLSTAAGGGGRQPRIYYGTILTGDQYLHCERTRNRLHHELGGMAVEMEGGAVAQICASFDIPWLVIRALSDLAGADSGVDFNRFVGEVAASSARVLLRLLPVLTAC
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: Y9702_DICDI
Sequence: MAGPWTLEPGKNYGGIPTWAWPRSTTVHVQVVGGGNGRVRFQAGASPDEDNDVNGETSFSRSFGGFRLNVTNIGSTTLKVWTA
What are the official names of this protein?
Uncharacterized protein DDB_G0269702.
Protein: LACB_STAHJ
Sequence: MKIAIGCDHIVTDTKMEVSQHLKAQGHEVIDVGTYDFTRTHYPIFGKKVGEKVASGEADLGVCICGTGVGISNAANKVPGVRTALVRDMTSALYSKEELNANVVSFGGKVAGELFIFDIVDAFIKAEYKPTEENKKLIAKINHLEAHNDNQANPHFFDEFLEKWDKGKYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: RBFA_CHRSD
Sequence: MREFKRTDRVADQLQQELAVLIQREIKDPRLGMVTVSSVKVSRDLGYADIYITLLGENDAARIDENLKVLRHARGFLRSQIANRIKLRHVPELRFHYDESVVRGQRLSSLIDEAVADDRRRHEDDDEDEVR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_MESFL
Sequence: MLFFGTYDHNLDDKQRLTIPSKMRNKILNSTVYVSKGFEGSLEMRTEEEFEKWSSQILNLSSFNKETRMITREIIANTHEVEIDKIGRIKIPNNLLKLANIEKSVYILGMGDRVEIWDQKSYDNYQNDNSDRMEEIAETIYQGLNK
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: IL1B_MUSPF
Sequence: MARVPEPTSEVMSYGYSDNENDLFFEADGPGKMKCCFQDLNNSYLEEEGIQLQISHQLHNKSLSHFVSVIVALEKLKKISVPCSLPLQGDDLMNVFHCIFEEEPIILEKCDDNAFVHDAPPRSLDCKFQDINQKSLVLYNSYELRALHLNGTSVNQQAVFRMTFVQEDEDITKIPVALCIKEKNLYLSCVMKDGKPTLQLEMLDPKVYPKKRMEKRFVFNKTEIKKKVEFESSQFPNWYISTSQAEAMPVFLGNNRGGHDITDFTMELSS
What is the function of this protein?
Potent pro-inflammatory cytokine.  Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.  Promotes Th17 differentiation of T-cells.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.  Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
What are the official names of this protein?
Interleukin-1 beta, IL-1 beta.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Secreted. Lysosome. Secreted, extracellular exosome. Note=The precursor is cytosolic. In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10.