PharMolix/UniProtQA huggingface dataset:
Protein: GUAA_STRP7
Sequence: MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHKISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGGKVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSADCPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKKIRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLGGKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHIVWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RSMH_ECO81
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGTYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_GRAFK
Sequence: MLAKQTERLSFSSVKNKPAYPDFLDLQIKSFQDFFQLETKSEERGNEGLYNTFLENFPITDTRNQFVLEFLDYFVDPPRYSIQECIERGLTYSVPLKARLKLYCTDPEHEDFETIVQDVYLGTIPYMTPSGTFCINGAERVVVSQLHRSPGVFFGQSFHANGTKLYSARVIPFKGSWIEFATDINSVMYAYIDRKKKLPVTTLFRAIGFERDKDILEIFDLAEEVKVSKTGLKKYLGRKLAARVLNTWYEDFVDEDTGEVVSIERNEIVLDRDTELEKDHIEEILETGSKTILLHKEDNQTGDYAIIHNTLQKDPTNSEKEAVEHIYRQLRNAEPPDEETARGIIDKLFFSDQRYSLGEVGRYRMNKKLGLDVEMDKQVLTKLDIITIVKYLIELINSKAEIDDIDHLSNRRVRTVGEQLSQQFGVGLARMARTIRERMNVRDNEVFTPIDLINAKTLSSVINSFFGTNQLSQFMDQTNPLAEITHKRRLSALGPGGLSRERAGFEVRDVHYTHYGRLCPIETPEGPNIGLISSLSVYAKVNGMGFIETPYRSVTDGKINTSEEPIYLSAEEEEGKKIAQANIPLKDDGTIDTDRVIARMEGDFPVVDPKEIHYTDVAPNQISSISASLIPFLEHDDANRALMGSNMMRQAVPLLRTDSPIVGTGLERQVATDSRVLINAEGEGEVEYVDANKIVIKYDRTEEERMVSFDDDSKSYNLIKFRKTNQGSCINLKPIISVGDRVTKGQVLCQGYATEAGELALGRNMKVAFMPWKGYNFEDAIVISEKVVRDDIFTSIHIDEYSLEVRDTKLGNEELTNDIPNVSEEATKDLDEHGMIRVGAEVKPGDILIGKITPKGESDPTPEEKLLRAIFGDKAGDVKDASLKASPSLSGVVINKKLFARAIKDKRKRAQDKEDVAALEKKYDAKFANLKADLVEKLFTIIGGKTAQGVQNDLGEEVMPKGKKYTLKMLNAVDDYTHLTTGTWTTDDHLNELVADLLHNYKIKENDLQGNLRREKFTVSVGDELPSGILKLAKVYIAKKRKLKVGDKMAGRHGNKGIVARIVRQEDMPFLEDGTPVDIVLNPLGVPSRMNIGQIYETVLGWAGQKNGKKYATPIFDGATIEEINDLTDKAGIPRYGHTYLYDGGTGMRFDQRATVGVIYMLKLGHMIDDKMHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGASATLREILTVKSDDVIGRAKTYEAIVKGEPMPEPGLPESFNVLMHELKGLGLDIKLEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MAME_MAGGM
Sequence: MTMFNGDVEDGGRSNVSCGKDLKRYLMLMGVVALVVLFGAFIYRQSSGGLRLGAMMEQMTGARGAVNVPAQHGAPSAVVDPAMSVPARARVAPPSAAGAIATFPPVVDFGPAPVVSGGPFTGVVTLLRNSVVSVTASSSGGQVMPDPLGLVNPDGLPRFANPTTRSVENIGTGVIVRNDGFIVTNYHVVRGANSVYVTVKDDVGSIRYSGEIVKMDEALDLALLKITPKVQLTAAVLGDSDAVNVADEVIAIGTPFGLDMTVSRGIISAKRKTMVIEGMTHSNLLQTDAAINQGNSGGPLVAANGTVVGINTAIYTPNGAFAGIGFAVPSNQARLFALDEVGWLPTSTAEGPAMGLVAMQRPMGVGVGAAGPVIAAGTPSPHVDGRQNMDCSNCHDIIPAGNGFQAPMMPVAAPVPPPPIPANAVSPHTDGRQNMTCNTCHQFVGGAAAGPIAFGQPMMPIAAPQQPAPAIRANAANPHTDGRQNMNCASCHQIIGSVGAAPIAAPGAGGAYRFSQPPGSLAINIQGPRGGQGAVAGSGGSRASLLGAALTPLTQRLGLQANLPAGRGVFVNGVTPNTPAASAGLRPGDVILKVDGRPVHQPEEVAAIMAEMPNGRSVRIGVLRAGDVSNMSLVTGPSGLAAAVVQAPTAPVVMAGGAPTVPGVQPVIPKVPTEFNWLGMEIETFMAPQPVVGMPGATPVAGGGKGAQVAEVLAGSRAAVAGLQANDLIIEVNNRPVTSPARLDAAIKAATAAGQQILLKVHRNGQEFWIVL
What is the function of this protein?
Acts at 2 distinct steps of magnetosome formation; required for correct localization of proteins to the magnetosome while the protease activity is required for maturation of small magnetite crystals into larger, functional ones (By similarity) (PubMed:20674739).  Probably cleaves at least itself, MamO and MamP; cleavage requires the putative transprot domain of MamO (By similarity).  Involved in localization of some proteins (at least MamA, MamC, MamF, MamI and MamJ) to the magnetosome (By similarity).  One of 7 genes (mamLQBIEMO) able to induce magnetosome membrane biogenesis; coexpression of mamLQRBIEMO in a deletion of the 17 gene mamAB operon restores magnetosome vesicle formation but not magnetite biosynthesis (PubMed:27286560).
What are the official names of this protein?
Magnetosome formation protease MamE, MM36.3, Magnetochrome MamE, Magnetosome serine protease MamE.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Magnetosome membrane; Single-pass membrane protein. Note=Purified magnetosomes remain attached to each other.
Protein: SYA_AGRFC
Sequence: MSGVNEIRSTFLDYFKKNGHEIVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGLESRPYSTAASAQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEEAITHAWNLITKEFGIDRNRLLVTVYHTDDEAFNLWKKIAGFSDDRIIRIPTSDNFWAMGDTGPCGPCSEIFYDHGDHIWGGPPGSPEEDGDRFIEIWNLVFMQYEQLTKEERIDLPRPSIDTGMGLERISALLQGKHDNYDTDLFRALIAASVEATGVPAEGEHRASHRVIADHLRSSAFLIADGVLPSSEGRGYVLRRIMRRAMRHAELLGSRDPLIYRLLPALIQQMGRAYPELVRAEALISETLKLEETRFRKTLERGLSLLSDATSTLHKGDMLDGETAFKLYDTYGFPLDLTQDALRAREIGVDISGFTDAMQRQKAEARSHWAGSGDKATETVWFELKEKFGATEFLGYDTESAEGVIQAIVRDGKEVDSAAEGETVHIVVNQTPFYGESGGQMGDTGVIVGDAGTFDVSGTQKKGEGLFVHSGTVSKGGLKVNEAVQLTVDHDRRSRLRANHSATHLLHEALREVLGTHVAQKGSLVAPERLRFDVSHPKPMSAEELKVVEDMANEIVLQNSPVVTRLMSVDDAIAEGAMALFGEKYGDEVRVVSMGTGLHGAKANRPYSVELCGGTHVAATGQIGLIRILGESAVGSGVRRLEAVTGQGALAYLAEQDERVKALASSLKVQPGDVLSRVEGLLDERKKLERELADARKKLAMGGGSSDAGANDVQQVAGVNFLAKSLSGIDAKDLKGLADEAKANLGSGVVLLIAVSDDGKASAVAAVTEDLTGRFSAVDIVRTASAALGGKGGGGRPDMAQAGGPDGTKAKEAIEAVAAALAA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPHN1_RAT
Sequence: MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGSALISAMRSYSSAVQKFSQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVQNASDLLIKPLETFRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLLEADLQVDKERHNFFESSLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCRYEKETRTLTMTPTEQKPGAKQGPVDLTLKYCVRRKTESIDKRFCFDIEANERTGTITLQAPSEANRRLWMEAMDGKEPIYHSPITKQEEMELNEVGFKFVRKCINFIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFYNSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQEDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEDSQVPPVPPPRVTARRHKPITISKRLLREKAVFYTPSLDDVEDEIHHPTPNGTIASNLDPPKQLQHLKLPMQKSGEMDPGRKSPSRPVSDCQTEPCLEADMGKLVYRLQDGGTKAIPKASNGPVPGSGHTKTSSFHIKRPAPRPIVHHKEGDTDCFSKVRPPGEKQTIIRPPVRPPDPPCRSSTSQKPESKPETVSSNAEEIPSSVVASRTRFFETASRKTGSSQGKLPGDES
What is the function of this protein?
Stimulates GTP hydrolysis of members of the Rho family.  Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function, in hippocampal neurons.  Critical for the stabilization of AMPA receptors at postsynaptic sites.  Critical for the regulation of synaptic vesicle endocytosis at pre-synaptic terminals.  Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.
What are the official names of this protein?
Oligophrenin-1.
What are the subcellular locations of this protein?
Postsynapse. Presynapse. Cell projection, axon. Cell projection, dendritic spine. Cell projection, dendrite. Cytoplasm.
Protein: CHLL_LEPBY
Sequence: MKLAVYGKGGIGKSTTSCNISVALAKRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQEKDYHYEDVWAEDVIYKGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFDEYDVILFDVLGDVVCGGFAAPLNYADYCMIVTDNGFDALFAANRIAASVREKARTHPLRLAGLIGNRTAKRDLIEKYVDAVPMPILEVLPLIEDIRVSRVKGKTLFEMAESDPSLNYVCDYYLNIADQILANPEGVVPKDAADRDLFSLLSDFYLNPQQPKTAEEELDLMMV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: MOAC_PARP8
Sequence: MPELTHFDAAGQAHMVDVGGKAETKRIAVARGTIRMLPATFELIRKGEAKKGDVIGIARIAAIQGAKRTADLIPLCHPLALTRVAVDFELDETVPAVHCRVQVETHGRTGVEMEALTAVQVGLLTVYDMCKAVDRGMTITDVKVMEKHGGKSGDWVAE
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: TPIS_CHLTR
Sequence: MFTDKETHRKPFPTWAHLLHSEPSKQFVFGNWKMNKTLTEAQTFLKSFISSDILSNPQIITGIIPPFTLLSACQQAVSDSPIFLGAQTTHEADSGAFTGEISAPMLKDIGVDFVLIGHSERRHIFHEQNPVLAEKAAAAIHSGMIPVLCIGETLEEQESGATQDILLNQLTTGLSKLPEQASFILAYEPVWAIGTGKVAHPDLVQETHAFCRKTIASLFSKDIAERTPILYGGSVKADNARSLSLCPDVNGLLVGGASLSSENFLSIIQQIDIP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_MYCMM
Sequence: MGAPTQIPIETSPLAWLDAVERQRRDAGLRRSLRPRPPVGTELDLASNDYLGLSQHPDVIEGGVQALRIWGAGATGSRLVTGDTELHQQLEAELAEYVGAAAGLLFSSGYTANLGAVVGLSGPGSLLVSDAYSHASLVDACRLSRARVVVTPHRDVAAVDAALASRDEQRAMVITDSVFSADGTLAPLRELLAACRRHRALLVIDEAHGLGVRGGGRGLLHELGLAGAPDVVLTTTLSKALGSQGGAVLGPAAVRAHLIDAARPFIFDTGLAPAAVGAARAALGVLKAEQWRPDAVLQNARELADICDVPETPQSAVVSVLLGDPEVALAAAAACLDAGVKVGCFRPPTVPAGTSRLRLTARASLSPDEMELARRVLTDVLLGPAAARR
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: BDSV_BUNCI
Sequence: GTTCKCGSTLGIYWFAVTSCPPGRGYTTHCGYF
What is the function of this protein?
Potently and reversibly blocks mammalian Kv11/KCNH/ERG voltage-gated potassium channels.  Acts as a gating-modifier toxin that shifts the voltage-dependence of ERG activation in the positive direction and suppresses its current amplitudes elicited by strong depolarizing pulses that maximally activate the channels.
What are the official names of this protein?
Toxin BcV.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RS6_XANAC
Sequence: MSRHYEVVFLVHPDQSEQVPAMIERYKSLIEGGNGTIHRLEDWGRRQLAYPIQNLVKAHYVLLNIEVDQAVLSELVESFRFNDAVLRHLVVKRDGADTEQSLIMKSKDEKGDKPERSERRRRDDEEGEAPAANDNDGDNAEAA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RK14_ARAHI
Sequence: MIQPQTYLNVADNSGARELMCIRIIGASNRRYAHIGDVIVAVIKEAIPNSPLERSEVIRAVIVRTCKELKRNNGTIIRYDDNAAVVIDQEGNPKGTRVFGAIPRELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YK004_HUMAN
Sequence: MGPWPRDWLGKGWRLGSCEARAGAKEVSVIRHGAPNPAQSHLHVQARAQVHSEDGHSLPPVVDGEDEVLSLLVFVQDSQECCRQAVQGRQGRGVTWGLGLPSYHLRTLLSPVCVPARDQRAPRKCCEAVLACPLVETLVTTLLTR
What are the official names of this protein?
Putative uncharacterized protein FLJ42569.
Protein: SYP_BRUO2
Sequence: MRLSRYFLPILKENPKEAEIVSHRLMLRSGMIRQQSAGIYSWLPIGLKVLNKVCTIIREEQNRAGANEILMPTIQSADLWRESGRYDAYGKEMLRIQDRQEREMLFGPTNEEMVTDIFRSYVRSYKDLPLNLYHIQWKFRDEVRPRFGVMRSREFLMKDAYSFDLDYEGAKMAYYRMFVSYLRTFARVGLQAIPMRADTGPIGGDLSHEFIILAETGESQVYCDRAYLDLAVPGADTDFRNDAQLTDIVTRWTTPYAATDEMHDEADWAKVKPESQVSARGIEVGHIFHFGTKYSEPMGAKVQGPDGKEHLVFMGSYGIGPSRLVAAAIEASHDDAGIIWPKAIAPFGAGIVNMKPGDEGCDGVSEKLYEALTNAGVDPLLDDKDERPGAKFATMDLIGLPTQVIVGPRGVAAGEVEVKDRKTGERQSLDIEAAINMLTAQA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPCA1_ARATH
Sequence: MSSRTGASLLLILFFFQICSVSALTNGLDASALNALKSEWTTPPDGWEGSDPCGTNWVGITCQNDRVVSISLGNLDLEGKLPADISFLSELRILDLSYNPKLSGPLPPNIGNLGKLRNLILVGCSFSGQIPESIGTLKELIYLSLNLNKFSGTIPPSIGLLSKLYWFDIADNQIEGELPVSNGTSAPGLDMLLQTKHFHFGKNKLSGNIPKELFSSNMSLIHVLFDGNQFTGEIPETLSLVKTLTVLRLDRNKLIGDIPSYLNNLTNLNELYLANNRFTGTLPNLTSLTSLYTLDVSNNTLDFSPIPSWISSLPSLSTLRMEGIQLNGPIPISFFSPPQLQTVILKRNSIVESLDFGTDVSSQLEFVDLQYNEITDYKPSANKVLQVILANNPVCLEAGNGPSYCSAIQHNTSFSTLPTNCSPCEPGMEASPTCRCAYPFMGTLYFRSPSFSGLFNSTNFSILQKAIADFFKKFNYPVDSVGVRNIRENPTDHQLLIDLLVFPLGRESFNQTGMSLVGFAFSNQTYKPPPIFGPYIFKADLYKQFSDVEVSSKSSNKSILIGAVVGVVVLLLLLTIAGIYALRQKKRAERATGQNNPFAKWDTSKSSIDAPQLMGAKAFTFEELKKCTDNFSEANDVGGGGYGKVYRGILPNGQLIAIKRAQQGSLQGGLEFKTEIELLSRVHHKNVVRLLGFCFDRNEQMLVYEYISNGSLKDSLSGKSGIRLDWTRRLKIALGSGKGLAYLHELADPPIIHRDIKSNNILLDENLTAKVADFGLSKLVGDPEKTHVTTQVKGTMGYLDPEYYMTNQLTEKSDVYGFGVVLLELLTGRSPIERGKYVVREVKTKMNKSRSLYDLQELLDTTIIASSGNLKGFEKYVDLALRCVEEEGVNRPSMGEVVKEIENIMQLAGLNPNSDSATSSRTYEDAIKGSGDPYGSESFQYSGNFPASKLEPQ
What is the function of this protein?
Leucine-rich repeat receptor protein kinase that acts as sensor of extracellular hydrogen peroxide (PubMed:32076270).  Required for intracellular calcium influx in response to extracellular hydrogen peroxide (PubMed:32076270).  Mediates hydrogen peroxide-induced activation of calcium channels in guard cells and is required for stomatal closure (PubMed:32076270).
What are the official names of this protein?
Leucine-rich repeat receptor protein kinase HPCA1, Protein HYDROGEN-PEROXIDE-INDUCED CALCIUM INCREASES 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: KCY_THEAB
Sequence: MPCRIAIDGPAGSGKTTVAKILADKLGIYYLDTGAMYRIIGLYLDKKGVENDSDIERELSTIKLEFINGDFYINGKRVGDEIRTPYAGICASKYAKKAIVREFLTRIQQKISKNENIVVEGRDIGTVVIPDAEVKIFLVASAEERAKRRYKELLDKGVKVSYEEVLNEIILRDKQDTEREIAPLRQPDDAVLIDSTKYTIEEVINKILEVVLEKCKLKLQKE
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_BREBN
Sequence: MSKVTGIVTELITPIVEEVGLELVDIEYKKEGSNWFLRVFIDNETGNIDIDDCRLVSEKLSEKLDEVDPIPTAYFLEVSSPGAERPLRKDKDFTKAVGRNVHITTKEPIEGATTFEGELVSYEDGKLTVKEAKKTYVISQEQIDTARMAIIF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_RHORT
Sequence: MSALVPPVLLASSSPSRGRLLSEAGVPFTAAAPGVDEQAIKASLKAEGVSARDAAIHLGEWKARRLSLAHPQALVIGGDQIAAIDDLWLDKPGSLATARQHLLLLRGRTHVLETAVVVLRDGQRLWHHLARPKMTMRSFSDAFLEDYLDRAGAGITACAGAYQIEGLGLQLFAAIEGDLFSIQGLPLLPLLDFLRPHGVLLS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_ANAD2
Sequence: MAHVAKKYKAAAEKVDRTKRYKLDEAMSLVKQTATKKFDETVDASINLGVDPKHADQVVRGAVVLPHGMGKTVRLAVFAKGDKAKEAQEAGADIVGAEDLAEKIQGGFMDFDKLIATPDMMGVVGRLGKILGPRGLMPNPKVGTVTMDLARAVKEQKAGKVEFRVEKAGIVHVPFGKASFDPDKLKANFSAIMEVIYKAKPQTAKGVYVKNVTLSTTMGPGIKVDLAELAAQHA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: H2AL3_HUMAN
Sequence: MAGNKMFCRPRRQRLSHSRRAELQFPVSHLERCLRESQHARHLSSTTPVFLAGVLEYLTANILEKVGKEVKNSCRLCITPEHVKRALQKDEQLRWILELEDDTHSQVEEMPQSEEEEEEEEEKEEEMVVLVVMGGRRRRRRRRRRKDS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A-like 3, H2A.L.3.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS15_HERAR
Sequence: MSLEKTSKAAIVADNARGANDTGSPEVQVALLTARINDLNGHFKAHSKDHHSRRGLIMMVNRRKSLLSYLKNKDATRYRDLIAKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: DUSA_SALTI
Sequence: MQPETQSSALPAYRFSIAPMLDWTDRHCRYFLRLLSRQTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAQLAHCAKLAEARGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDDQDSYAFLCDFINTVSGQGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDFPHLTMSINGGIKSLEEAKEHLRHMDGVMVGREAYQNPGILAAVDREIFGADTTDTDPVAVVRAMYPYIERELSQGAYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADAAVLEQALKLIADKR
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U20 and U20a in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(20/20a) synthase, U20-specific dihydrouridine synthase, U20-specific Dus, tRNA-dihydrouridine synthase A.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusA subfamily.
Protein: FXC1B_XENLA
Sequence: MQARYSVSSPNSLGVVPYLSGEQSYYRAAAAAAAAGGGYTGMAAPMSMYSHPAHEQYQAGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKDATKEDKERLLKEHNGSQSAAAQQQRQQQNQAQAEQDGSSQPVRIQDIKTENGTSSPPQSMSPALSAVPKIESPDSSSSMSSGSPHSIPSNRSMSLEAAESHHPHQQQHHHHSQGFSVDNIMTSLRGSPQGSGELPSPLISSSRTGIAPSLSLTYSPSQGSIYSPPCSQGSSSGGGAGTYHCNMQAMSLYSGDRSGHLTPANTPAATTVEETLPDYSITTTTSALSHGNQEHPHQGRLPSWYLNQTGDLGHLAGASYPGQQQNFHSVREMFESQRLGLNSSPVNGNSSCQMSFPPSQSLYRTSGAFVYDCSKF
What is the function of this protein?
DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development.  Acts either as a transcriptional activator or repressor.  Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes.  Upon DNA-binding, promotes DNA bending.  Required for cell viability and resistance to oxidative stress in the eye.  Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1-mediated signals.  Involved in epithelial-mesenchymal transition (EMT) induction by increasing cell proliferation, migration and invasion.  Involved in chemokine-induced endothelial cell migration.  Plays a role in epidermal keratinocyte terminal differentiation.  Essential developmental transcriptional factor required for mesoderm-derived tissues formation, such as the somites, skin, bone and cartilage.  Plays a role in the development and maintenance of mesenchymal niches for haematopoietic stem and progenitor cells (HSPC).  Plays a role in corneal transparency by preventing both blood vessel and lymphatic vessel growth during embryonic development in a VEGF-dependent manner.  Plays a role at the gastrula stage for expression of several mesodermal and endodermal genes.  At the late neurula stage, regulates expression of adhesion genes to maintain cell adhesion in the mesodermal germ layer.
What are the official names of this protein?
Forkhead box protein C1-B.
What are the subcellular locations of this protein?
Nucleus.
Protein: PFKA_YERPY
Sequence: MVKKIGVLTSGGDAPGMNAAIRGVVRAALSAGLDVFGIEDGYLGLYENRMKKLDRYSVSDMINRGGTFLGSARFPEFRDPEVRKVALKNMHERGIDGLVVIGGDGSYAGADLLTKEGGIHCVGLPGTIDNDVAGTDYTIGFFTALETVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIAIPEVEFKRDDLVAEIKAGIAKGKKHAIVAITEKLDDIDSLAKYIEKETGRETRGTVLGHIQRGGAPVAYDRILASRMGSYAVDLLLQDHDYKKGGFCVGVQNEKMVHELISVCIAPENKKSKFKEDWYDTAKKLF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.