PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_UREPA
Sequence: MQNNKNYTEKFITDKVMRRDYSKIKSNFEGPNLLEIQVESFKRFMEKDLKEVISSIFPLKSPQGKYTLAFKGLKIKQPTKDESACRDEGKTFETPIYIDLELTDNYTGEVKRAQRNTKTGEDGIYLGAIPKMTEKGTFVINGIEKFVISQIVRSPGIYVLGKSSIKLNGSRKRLFEGKICEIYPSKGTLMLGYIPKDRHNIQIVARDSSGDNAQTFSVTTLLKAFGLTSAEILKIFNNEKEIRESLEIEKYAPEYIFENSQENEIIFKIYSDAHDIHEKADRRESNNKLKEEYIEQGSPLLSKLKQLIFNYVEKNDEIDALLHENKDVEDASFIKNNKKLYDEREEIINCIISEKAAKDIVELLGINIKNIETLRHLGKASYQIALQQHFFNKRLYDISSAGRYKFEKKLLLSERLYQKVIANDIIDKKNNILIPKDTLITKEHIELIKKESRDKNIKWTKKINLLPTALESEIEQFLEYESIAVYKDNDLRDETTEIVGLASGCKLQTLTVADLVATTSYIYNLNYEIGEFDDIDHLGNKRLKLIHELLRARIATSMARIEKFINEKLAISDGSSNNITNVNDKGIDTELDREIEESDMSDEEKKKAISVKSIINTKQFQSLVKDFFNSHQLIQFIDQQNPLAELTNKRRISAMGPGGISREDPNLDIRDVHHSHSSRICPIETPEGMNIGLIMSLASLAKVDENGFIVAPYYVVEDGVVKEDYKYLTAHEDDNYIIAESSVQLDENKRILDEQVVARYRGSTGLFSPNEVDFIDIVPKQVVSIAASAIPFIENDDGARALMGSNMQRQATPLIKPYAPIVGTGTEFKIAHDSGMAVVAKNDGVVEFVDSQKIIIRNDNDKLDDYKLIKYRKSNQDTCNNQIPIVKVGQRVHKSETIGDGPAMQNGELALGRNILVGYTTWRGYNFEDAIIISERLVDQDVFTSIHIDEHTIQCMKTKNGDEEITRDMPNVSDTAKRFLDNQGIVLVGAEVHEGDVLVGKTTPRGNVETAPEDRLLQTIFGDKSKTVKDSSLKVKHGQEGIVAAVKRIKSSDENGSELPDDVIEIIKVYIVQKRKIQVGDKMAGRHGNKGIVSKVVPIQDMPFLKDGTPLDIMLNPLGVPSRMNIGQILELHLGYAAAEIGKKQLIQIAIDQLGYEKYISLFGINEIIAKKLYENISNLIKHKQAKQAKDIDLIDVTIILKELGLSYDDIGIKISTPVFDGANHDDIVSIMNEANIDIENNKGKQVLYDGRTGEPFDGLISVGLTYMLKLDHMVDDKIHSRSVGPYSKITQQPLGGKSQNGGQRFGEMEVWALEAYGAAYNLLEILTIKSDDVQGRNQAYNAIIKGHDVVADGMPESFKLLTKQMQGLGLCITVETKDDRMVDINEYTLNQNRLNNDDDEVILDENLKEINDSNEEIFNTNFNNNDYDDEENF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TRIM5_MACFA
Sequence: MASGILLNVKEEVTCPICLELLTEPLSLHCGHSFCQACITANHKKSMLYKEGERSCPVCRISYQPENIQPNRHVANIVEKLREVKLSPEEGQKVDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEEVAQEYHVKLQTALEMLRQKQQEAEKLEADIREEKASWKIQIDHDKTNVLADFEQLREILDREESNELQNLEKEKEDILKSLTKSETKMVQQTQYVRELISDLEHRLQGSMMELLQGVDGIIKRIENMTLKKPKTFHKNQRRVFRAPDLKGMLDMFRELTDARRYWVDVTLAPNNISHAVIAEDKRQVSSRNPQIVYQSPGTLFQSLTNFNYCTGVLGSQSITSGKHYWEVDVSKKSAWILGVCAGFQSDAMCNIEQNENYQPKYGYWVIGLQEGVKYSVFQDGSLHTPFAPFIVPLSVIICPDRVGVFVDYEACTVSFFNITNHGFLIYKFSQCSFSKPVFPYLNPRKCTVPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Restricts infection by human immunodeficiency virus type 1 (HIV-1) (PubMed:22291694).  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2 (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: RL17_FELCA
Sequence: MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_BORBU
Sequence: MAITYSIGDMLTKLRNASRVGHGSVDLKMSNMNKSILNILKEEGYIKDFNFLEKKGIAFIRVLLKYDNKRNPVINKIDAISTPGRKIYSSYRNMPRIKNGYGILIISSSQGVITGKEAKDKKIGGELICSVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: G6PD_ASPNG
Sequence: MASTIARTEERQNAGTMELKDDTVIIVLGASGDLAKKKTFPALFGLYRNKFLPKGIKIVGYARTNMDHEEYLRRVRSYIKTPTKEIEEQLDSFCQFCTYISGQYDKDDSFINLNKHLEEIEKGQKEQNRIYYMALPPSVFTTVSDQLKRNCYPKNGVARIIVEKPFGKDLQSSRDLQKALEPNWKEEEIFRIDHYLGKEMVKNILIMRFGNEFFNATWNRHHIDNVQITFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQVLTLLAMERPISFSAEDIRDEKVRVLRAMDAIEPKNVIIGQYGKSLDGSKPAYKEDETVPQDSRCPTFCAMVAYIKNERWDGVPFIMKAGKALNEQKTEIRIQFRDVTSGIFKDIPRNELVIRVQPNESVYIKMNSKLPGLSMQTVVTELDLTYRRRFSDLKIPEAYESLILDALKGDHSNFVRDDELDASWRIFTPLLHYLDDNKEIIPMEYPYGSRGPAVLDDFTASFGYKFSDAAGYQWPLTSTPNRL
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity).
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: CYB_ZUCRI
Sequence: MASLRKTHPLLSIVNNALVDLPAPSNISVWWNFGSLLGLCLITQLITGLFLAMHYTSDISMAFSSVVHICRDVNFGWLIRSIHANGASFFFICIYMHIARGLYYGSYLYKETWNVGVVLLLLVMATAFVGYVLPWGQMSFWGATVITNLLSAVPYIGNALVQWIWGGFSVDNATLTRFFAFHFLLPFVIAAATMIHLLFLHETGSNNPAGLNSDADKISFHPYFSYKDLLGFIILLMALTSLALFSPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLMLVPILHTSKQRGLTFRPLTQLLFWALVADVLVLTWIGGMPVEHPFVIIGQVASALYFLLFLVLSPAASWLENKTLEWS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARC_MYCBO
Sequence: MGESERSEAFGIPRDSPLSSGDAAELEQLRREAAVLREQLENAVGSHAPTRSARDIHQLEARIDSLAARNSKLMETLKEARQQLLALREEVDRLGQPPSGYGVLLATHDDDTVDVFTSGRKMRLTCSPNIDAASLKKGQTVRLNEALTVVEAGTFEAVGEISTLREILADGHRALVVGHADEERVVWLADPLIAEDLPDGLPEALNDDTRPRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVSYADIGGLSRQIEQIRDAVELPFLHKELYREYSLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAHEAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIYSKYLTEFLPVHADDLAEFDGDRSACIKAMIEKVVDRMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKNAIKSVLETGQPGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSASRAIDTESNLGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Mycobacterial proteasome ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: SECB_ACIAD
Sequence: MSEEQQTQPQLALERLYTKDISFEVPGPQVFTKQWQPELNINLSSSAEKIDPTHFEVSLKVVVQANNEGETAFIVDVTQSGIFLIDNIEEDRLPYILGAYCPNILFPFLREAVNDMVTKGSFPQLLLTPINFDAEFEANLERAQTAVEGQA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_SHEAM
Sequence: MAKVEAQQQKDDLQEKLIAVNRVSKVVKGGRIFSFTALTVVGDGNGRVGYGYGKAREVPAAIQKAMEKARRNMVTVELNEGTLHHPVKGRHTGSRVYMQPASQGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATVDALTHMKSPAQVAAKRGLSVEEIRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PG021_MONPZ
Sequence: MEFDPVKINTSSIDHVTILQYIDEPNDIRLTVCIIRNINNITYYINITKINPHLANRFRAWKKRIAGRDYMTNLSRDTGIQQSKLTETIRNCQKNKNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNTYTPNTPNNTTTISELDIIKILDKYEDMYRVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHRTRRETGALDNCPICRTRFRKITMSKFYKLVN
What is the function of this protein?
RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  Plays an important role in virulence by acting as an anti-apoptotic factor.
What are the official names of this protein?
host range factor p28, E3 ubiquitin-protein ligase p28, Protein D5R.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG021 family.
Protein: DCUP_PONAB
Sequence: MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCEPTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLECLRDPEVVASELDYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVAAGAQALQLFESHAGHLGPQLFSKFALPYIRDVAKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
What is the function of this protein?
Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway.  Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme.  In vitro also decarboxylates pentacarboxylate porphyrinogen I.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAS1_DROME
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLASWNVNNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKDKDNKGRRGRKMNKPNRRFKCKML
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity).  Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells (PubMed:11290305).  During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis (PubMed:19965758).
What are the official names of this protein?
Ras-like protein 1, Dras1, Dmras85D.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Loss of prenylation causes protein location to the cytoplasm.
Protein: YONR_BACSU
Sequence: MFGERLKKCRTSKGYSQQRMADFLGITRQGYGKYEIGKAEPDLKTLTKLSNILGVSTDFLLKGTHAQFDLDEILNDPETLIAGYNGMISEEQAKELLYYLLKKEFEEH
What are the official names of this protein?
SPbeta prophage-derived uncharacterized HTH-type transcriptional regulator YonR.
Protein: T2TA_THEAQ
Sequence: MASTQAQKALETFERFLASLDLESYQQKYRPIKTVEQDLPRELNPLPDLYEHYWKALEDNPSFLGFEEFFDHWWEKRLRPLDEFIRKYFWGCSYAFVRLGLEARLYRTAVSIWTQFHFCYRWNASCELPLEAAPELDAQGIDALIHTSGSSTGIQIKKETYRSEAKSENRFLRKQRGTALIEIPYTLQTPEELEEKAKRARVNGETYRLWAKVAHHLDRLENGFVIFRESYVKSIELFLQKNAPTLSGLIRWDRVAQEALTAP
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-TCGA-3' and cleaves after T-1.
What are the official names of this protein?
Type II restriction enzyme TaqI, R.TaqI, Endonuclease TaqI, Type-2 restriction enzyme TaqI.
Protein: TTFA_MYCS2
Sequence: MVPLWFTLSALCFVGAAVLLYVDIDRRRGLGRRRKSWAKSHGFDYEYESEDLLKRWKRGVMSTVGDVTAKNVVLGQIRGEAVFIFDIEEVATVIALHRKVGTNVVVDLRLKGLKEPRENDIWLLGAIGPRMVYSTNLDAARRACDRRMVTFAHTAPDCAEIMWNEQNWTLVAMPVTSNRAQWDEGLRTVRQFNDLLRVLPPVPQNGSQAALPRRGGSPSRPLAPTPAGRRELPPGRADVPPARGDVSRFAPRPEAGRSDAFRRPPPARNGREASHFQR
What is the function of this protein?
Required for MmpL3-dependent trehalose monomycolate (TMM) transport to the cell wall.  Required for growth and cell elongation.
What are the official names of this protein?
Trehalose monomycolate transport factor A, TMM transport factor A.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Cell septum. Cell tip. Note=Colocalizes with MmpL3 to the cell poles and septa. Trehalose monomycolate (TMM) synthesis is not required for localization to the poles or septa.
Protein: SYC_PYRAR
Sequence: MRIYNTATRQLEEFVTYTPRLARGYVCGITPYDSVHVGHGRVYVFFDMFRRYLEAQGYEVRLVINFTDIDDKIINRAREEFGAEAYKRWREVPERYIAEFFEMSKRLFIKPAYAYPKVTENVEDMVSWIKALVEKGYAYTAPDGSVYFEVGKVPNYGVLSRQRIEELMAGARVEPEPGKRNPLDFALWKSWTPGEPWWESPWCPGRPGWHLECVVMSTKHLGVPFDFHGGGADLIFPHHENEIAIAKAYFGVDNFARYWIHVGYLTVRGEKMSKSLGNVVTLREALSKYSGEALRLAYAMSHYRKPMEFSYEVLDQAEEMAKTIYTAYDELGQAVGDAGEEDKEALDYGRYVEEFYAALEDDFSTPQAAQQFYGLARYIISTVLHKIDKISRNTALSILSQYVKMADILGVLERREVPKEVEEAVKAAVEVRAKLRKERQYQLADYIRERLAGIGVELHDFGQRTYYTYRRGNRLR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYC_ONCMY
Sequence: NSSLASKNYDYDYDSIQPYFYVDNEDEDFYHQQPGQLQPPAPSEDIWKKFELLPTPPLSPSRPSLSSIFPSTADQLEMVTEFLGDDVVNQSFICDADYSQTFLKSIIIQDCMWSGFSATAKLEKVVSERLASLQTARKDSAVGDNAECPTRLNANYLQDPNTSASECIGPNTSASECIGPSVVFPYPITETPKPSKVAPPTDLALDTPPNSGSSSSSGSDSEDDDEEEDDEDEEEIDVVTVEKRQAVKRCDPSTSETRHHSPLVLKRCHVSTHQHNYAAHPSTRHEQPAVKRLRLENSSSRVLKQISSNRKCSSPRTSDTEDYDKRRTHNVLERQRRNELKLSFFALRDEIPDVANNEKAAKVVILKKATECIYSMQTDEQRLVNLKEQLRRKSEHLKQKLAQLQNSCLSSKRH
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.
What are the official names of this protein?
Transcriptional regulator Myc, c-Myc.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSD_CITBB
Sequence: MRNTDTPIAVEGYPFIAGFAAATLLLALLGQFLHCGFFVPATLFFVLTVFTVFFFRNPERATPGDENTVVAPADGEVIFLGKVIEPHTNGEFEKISIFMSVFNVHVNRAPISGKVVDGFYTKGKFFDVRDERASFENEQQGLVLETAAGLRMVVVQVAGLIARRIVCYAKTGDSLSRGRRYGLIRFGSRLDIYLPLGTSIDVVMGQKTVAGETVLGILP
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYRD_CYAP4
Sequence: MNVYQSLLQPFVFQTLRADPETVKLQLLRLGESIERHSDRPPARWIKQQLAQTFSLPTPELSQQLWGLTFPNPIGLAAGLDKDGVAAGLWGSFGFGFAEVGTVTYHPQPGNPRPRLFRLPADRAGINRMGFNNRGAAALAQTLEQAQKRSARTIPLGINLGKSKVTPLEEAVEDYLGSFRLLQAWGDYFVINVSSPNTPGLRSLQTAANLEPILSALQNENQARRPLLLKISPDLAWEDLATIIDLVKTYQWAGLIATNTTIARPELQTKVIPQTGKSPQEEAGGLSGAPLKQRSTEVIRFIHQQTGGQLPIIGVGGVFTAADAWEKIMAGATLIQVYTGWIYEGPGMVKQLLTGLQTELQQRGLDCLAALDRQP
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: THIM_VIBC1
Sequence: MLIEQITQALTAVRQQKPLVVNITNYVVMNNTANALLAIGASPIMAHSKQEMVEMMSFAGALVINIGTLDSVWTPRMSYAVEQANANGKIVVLDPVGCGASSLRTETSREIARLADKLIIRGNASEIIALAGEQAQSKGVDALDSSDAALGAANFLVAEYGASVVISGETDYIVTKGQTVQLNNGHEMMPYVTGMGCTLSALTGAFAAVGDDTGLAAAAVLGVVGEIAAEQARGPGSLQMNLLDELYQLDEETLAKRLKMQVS
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: ECFA1_STRPQ
Sequence: MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGSGKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDDVAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPKIIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQVESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPIDYGYLTEKELENQLCQLISKM
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y756_LYSSC
Sequence: MITGYKPHELGIFNDKHPRIGIIKKALENRLRLLLDEGLEWVIISGQQGVESWSAEVVWTLKKEFPHLKYAVITPFLEQEKNWQDPKKEKYQTIIARADFVTSITKKPYEAPWQFIEKDKFIIQNTDGLLLIYDEENEGSPKYIKRLAEKFMESHDYSLLTINAYDLQMIAEEIQQQDW
What are the official names of this protein?
UPF0398 protein Bsph_0756.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: DNAA_STAA1
Sequence: MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLSSIPFNANWLNQQYAEIIQAILFDVVGYEVKPHFITTEELANYSNNETATPKETTKPSTETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLIDDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIVDITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLLGKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEIRNV
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1837_SHEHH
Sequence: MICAVYKSRRKAESYLFVEKRNDFERVPEALMDMFGEPQLVMMLPIEKRDHLGFADIKKVRSELKEKGFYLQLPPPVVNLLEQHKKEIGFNPD
What are the official names of this protein?
YcgL domain-containing protein Shal_1837.
Protein: PUR5_SALPA
Sequence: MTDKTSLSYKDAGVDIDAGNALVDRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDAIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTAASVINGIAEGCLQSGCALVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSRVAEGDVLIALGSSGPHSNGYSLVRKIIDVSGCDPQTTLLEGKPLADHLLEPTRIYVKSVLELIENVDVHAIAHLTGGGFWENIPRVLPENTQAVINESSWQWPAIFTWLQTAGNVSRHEMYRTFNCGVGMVIALSAPEADKALALLNEKGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KXDL1_DROME
Sequence: MSHLGLADVHQSEDATPDLESFTGFGNSAAEAFIQSLAGMVNQGDVETMIRAQKQMLQRFEKTNEMLLNCNALSQSRLKSASEDFKRHVKCLSEMKKDLDYIFRKIRIIKQKLQSQFPAIYAEVQPQRSSLAEEAEDDTEAQAKKTAETPAPAAAKPVLSTKKSAATIEYVQMEEAVDNGTVEIENELIKRVCSVETANPNDSSDCTSEDTG
What are the official names of this protein?
KxDL motif-containing protein CG10681.
What is the protein family that this protein belongs to?
Belongs to the KXD1 family.
Protein: RS5_WOLTR
Sequence: MTIKNFQNNNDWSELLVSVRRVTTVTKGGRRFSFSILVVVGDEKGRVGCGMGKHAEVAEARIKAVNAAKKSMIRVYLREGRTLHHDIKAKFCSGEIVLRAARAGTGIIAGGAIRSVFEVLGIKDVVAKSTRSNNPHNVICAVFKAFDNMLSPRQVASKRGKKISEVVGNR
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RL22_MYCTU
Sequence: MTAATKATEYPSAVAKARFVRVSPRKARRVIDLVRGRSVSDALDILRWAPQAASGPVAKVIASAAANAQNNGGLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVESRPAKDQRSAKSSRARRTEASKAASKVGATAPAKKAAAKAPAKKAPASSGVKKTPAKKAPAKKAPAKASETSAAKGGSD
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: F162B_BOVIN
Sequence: MLATVGSLLRLRLGRIPCCAPGAPPEVERRPVASLWPRGHPQYSCGGSPGSSEPPGSAEKVHRVPAEHKPSQFDKRILLWTGRFKAMEDIPPRIPPEMIDAARNKARVKACYIMIGLTIIACFAVIASAKRAAERHESLTSWNLAKKAKWREEAALAAQAKAK
What are the official names of this protein?
Protein FAM162B.
What is the protein family that this protein belongs to?
Belongs to the UPF0389 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.