PharMolix/UniProtQA huggingface dataset:
Protein: HEMA_I53A0
Sequence: MYKIVLVLTLFGAVNGLDKICLGHHAVPNGIIVKTLTNEKEEVTNATETVESKTLDRLCMKGRKYKDLGNCHPIGIIIGAPACDLHLTGRWETLIERENSIAYCYP
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: VAX2_RAT
Sequence: MGDGGAERDRGPKRREEPGGRSGCRGEHRGAEDLRADTGSTSPREIAGTSASSPAGSRESGGDSDGQQALGETDHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSAFEAFATSNVLRLLEQGRLLSVPRAPSLLALSPGLPGLTAGHRGTSLGDPRNSSQRLNPMPSASASSPLPPPLPAVCFSAAPLLDLPASYKLGSSAFEPYSRLEQQKVGSPGQSDKKADI
What is the function of this protein?
Transcription factor that may function in dorsoventral specification of the forebrain.  Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist.  Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle (By similarity).  May be a regulator of axial polarization in the retina.
What are the official names of this protein?
Ventral anterior homeobox 2.
What is the protein family that this protein belongs to?
Belongs to the EMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DTHD_MYCS2
Sequence: MTQAQELSVDFDFRLDGKVALVTGAASGIGAAIASAYATKGARIAAVDLNAEGAEALAAQLGGDRGAHRGFACDVADAASVQAAADAVAAEFGRIDILVNSAGVARLAPAEELSLQDWDSTLAINLSGTFLMCQAVGKRMLEAGGGAIVNMASQAATVALDQHVAYCASKFGVVGVSKVLAAEWGGRGVRVNTISPTVVLTELGHKAWDGPRGDALKKLIPTGRFAYPDEIAAAAVFLASDAAAMINGADLVIDGGYTIK
What is the function of this protein?
Catalyzes the NAD-dependent reversible oxidation of D-threitol.  Involved in the degradation pathway of D-threitol, that allows M. smegmatis to grow on this compound as the sole carbon source.  Does not catalyze the oxidation of xylitol, L-sorbitol, and L-sorbose.
What are the official names of this protein?
D-threitol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: EGR1_CHICK
Sequence: CDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKVEKAASVSATSSSVAAYSSSVATSYSSSIATTYPSSVRTVYSSPASSSYPSPAHTTFPSPSIATTYSSGTATFQTQVATSFPSPGVTNNFSSQVTSALSDMTSTFSPRTIEIC
What is the function of this protein?
Transcriptional regulator.  Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity).  Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity).  Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia.  Plays a role in the regulation of cell survival, proliferation and cell death.  Mediates responses to ischemia and hypoxia; regulates the expression of proteins that are involved in inflammatory processes (By similarity).  Plays a role in regulating the expression of circadian clock genes (By similarity).
What are the official names of this protein?
Early growth response protein 1, EGR-1, Zinc finger protein ZENK.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: STTB_ASPTE
Sequence: MSISNMTSTVWPDLQVPAVEYNHLPILTVALLTVIASAVYINVSSAQDPYKVSSIPTVKRPRVLDAYRSGVWWRIFVPRLVPYIEEGYHKYNKNDQPFRIWLGGFQTYAYVLPERYLEKIKNMPESEASFAAMANKYFHTGLPTGEVNNLVLQVASKLVNGNLATIKTLMQGEVQKALAREIGSPRQWTKINAWQVARKTTEAPGLRVVFGEELANDKTFVTGVSEFVSNITVYAFTLRYINLGPLRDFILYLVHWRHRRSLPAVLTPLNNVITERKKVRSNRHISDDEESFDCIQWALDQPVSDDCKTAEAIARRLVVISLGTIDTVAGVLVKQLTHLASHPECHEAIRAEIRECLAEDDKGWTLKSSARMKKLESFIQESLRMSSGAISLSGMRIVTGPGFRLDDNTILPRDSFIAIPTRNILYDPEVFPEPEKFDPFRFYKIKEDEKNAGPLSNRRDIRASWLAFGYGRQACPGRFYAINAMKAILGEILLKYDIRLAEKQAPSIDIDLDPMLAPARSTDLEFRVRA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aspterpenacids (PubMed:28604695, PubMed:34085529).  Performs the C22-oxidative modification of the terpene synthase sttA product preaspterpenacid I to produce preaspterpenacid II (PubMed:34085529).  It has still to be determined how preaspterpenacid II is further modified to produce aspterpenacids (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase sttB, Aspterpenacid biosynthesis cluster protein sttA, Ophiobolin family sesterterpenoid biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MTNN_YERPB
Sequence: MKVGIIGAMEEEVTLLRDRIENRQTLARAGCEIYTGQLNGIDVALLKSGIGKVAAAMGTTLLLEHCQPDLVINTGSAGGLASSLKVGDIVVSNEVRYHDADVTAFGYEPGQMAGCPAAFVADEDLIALAENCIQQLKLNAVRGLICSGDAFINGAEPLARIRAAFPTVAAVEMEAAAIGHVCYLFNTPFVVVRAISDVADQASHLSFEEFLVVAAKQSTLMIEAMLTTLAQRG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: AROC_CERS4
Sequence: MSYNTFGHIFRVTTWGESHGPALGATVDGCPPGVAIEAEAIQHWLDRRKPGQNRFTTQRQEPDAVRILSGTFEGRSTGTPIQLMIENTDQRSKDYGEIARSFRPGHADIAYHWKYGLRDYRGGGRSSARETAARVAAGGVARAALAALVPGLRIEGYMVQIGPHAIDRARFDADEIERNPFWCPDPDTAALWADYLDGLRKAHDSVGAIVEVRASGVPAGLGAPIYGKLDSDLAAAMMTINAVKGVEIGEGMAAACLTGSANADEIRMGPEGPEFLTNHAGGILGGISTGQDVVVRFAVKPTSSILTPRRSVTTDGREVEVVTKGRHDPCVGIRAVPVGEAMMACVLLDHLLLDRGQTGGLRGTIG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: YFJR_ECOLI
Sequence: MTQAERRHDRLAVRLSLIISRLVAGETLSVRKLAAEFGVSVRTLRRDFRERLMYLDLEYQSGYCRLRTAGSEMQMVPDVLIFAHRSGLAGLFPGLDRRLVNALLMCDESPCVIAPANPVPSPSGALSFWRLIQAITGRRRVTLIAEGRRCERLAPCRLLIHQQTWYLVAEHEGHIAVFTLDEIHLIQPLQETFRRNDSLCRLVEDPVFIQALPHFRFIQHSLLTFVPADSPPE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YfjR.
Protein: IHFB_CHRVO
Sequence: MTKSELIARLSERLAERNSQLVYKDAELAVKTILDAMANNLAQGSRIEIRGFGSFDLNYRPPRVGRNPKSGASVSVPEKYVPHFKAGKELRERVDLSLLEQTQA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RL11_GEMAT
Sequence: MAKKVTGFVKLQIPAGKANPAPPVGTALGPQGINIMGFCKEFNARTQGGDMIIPVEVTIYADKSFTFILKTPPAAELIKKELGVERGSGQPNKVKVGTITRAQLEKIATTKMPDLNCESMESAVAMIAGAARSMGITVKD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: HBB_PANPA
Sequence: MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GBB_LOLFO
Sequence: MTSELEALRQETEQLKNQIREARKAAADTTLAMATANVEPVGRIQMRTRRTLRGHLAKIYAMHWASDSRNLVSASQDGKLIVWDGYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFIDDNQIVTSSGDMTCALWNIETGNQITSFGGHTGDVMSLSLAPDMRTFVSGACDASAKLFDIRDGICKQTFTGHESDINAITYFPNGFAFATGSDDATCRLFDIRADQEIGMYSHDNIICGITSVAFSKSGRLLLGGYDDFNCNVWDVLKQERAGVLAGHDNRVSCLGVTEDGMAVATGSWDSFLKIWN
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
Protein: RS7_HYDS0
Sequence: MPRKGRVPRREILPDAKYNSIIVHKLINKVMKDGKKSTAEYIVYTALERVAEKLNLSPVEVLEKALENVKPVWEVRPRRVGGATYQVPVEVEEHRRESLGIKWLVDAARERARHRGSYTMEERLAAEIMDAIENKGAAVKKKEDTHRMAEANKVFAHFKW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL11_ACIBS
Sequence: MAKKIDGYIKLQVPAGKANPSPPIGPALGQRGVNIMAFCKEFNAATQKVEPGLPIPVVITVYNDKSFTFIMKTPPASILLKKAAGIQKGSSVPNKTKVGKLTRAQLEEIATTKEPDLTGADLDARVRTIAGSARSMGLEVEL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CAPP_ECOLC
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKSSRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQLDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARLKGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVRIDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAETREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKELRNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKEGQEPDPRVEQALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: IXTPA_STAAS
Sequence: MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRNAINLLQAFLEGDKNV
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: RSMG_BURCM
Sequence: MTARRAPAVNRDVLEQMLVDGTAALDIALTDAQRNQLLDYVALLGKWNAVYNLTAIRDPKQMLIQHILDSLSIVPHLRDRASARVLDVGSGGGLPGIVLAIVRPDWQVTLNDIVQKKSAFQTQMRAELKLANLSVVTGRVELLQPGVDVPEKFDMIVSRAFADLSDFVKLARHLVAPGGSIWAMKGVHPDDEIARLPEGSRVKQTMRLAVPMLDAERHLIEVIVDEAN
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_THET2
Sequence: MASEVRIKLLLECTECKRRNYATEKNKRNTPNKLELRKYCPWCRKHTVHREVKI
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: VDRB_DANRE
Sequence: MESAVSTSTQVPDEFDRNVPRICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKASFTCPFNGSCTITKDNRRHCQACRLKRCLDIGMMKEFILTDEEVQRKKELIQRRKDEEAHREAQKPRLSDEQRNIIDTLVDAHHKTYDDSYSDFSRFRPPVREGPVTRSASRAASLHSLSDASSDSFSHSPESGDRKMNLSNLLMMYQEQGLSSSPDSKEEDGSSLSMLPHLADLVSYSIQKVIGFAKMIPGFRELTAEDQIALLKSSAIEVIMLRSNQSFSLEDMSWSCGGPEFKYCVNDVTKAGHTLELLEPLVKFQVGLKKLNLHEEEHVLLMAICLLSPDRPGVQDHVRVEALQDKVSEVLQAYIRAHHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGGQVT
What is the function of this protein?
Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells.  Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR.  The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes.  Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association.  Plays a central role in calcium homeostasis.
What are the official names of this protein?
Vitamin D3 receptor B, VDR-B, 1,25-dihydroxyvitamin D3 receptor B, Nuclear receptor subfamily 1 group I member 1-B.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes mainly to the nucleus. Translocated into the nucleus via both ligand-dependent and ligand- independent pathways; ligand-independent nuclear translocation is mediated by IPO4.
Protein: RK16_CHAGL
Sequence: MLSPKRTKFRRHHRGRMKGISSRGNFIAFGKFALQALEPSWITSRQIEAGRRAMTRYARRGGKIWIRIFPDKPVTMRAAETRMGSGKGSPEFWVAVVKPGRILYEMSGVSESIAKSAMRIAAFKMPIKTQFLVKKDKV
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KUP_FLAPJ
Sequence: MSASSHHDLHSKLSLGGILVTLGIIYGDIGTSPLYVMKSIIGLHTIKPEVVLGGISAIFWTLTLQTTLKYVLITLSADNHGEGGIFALYALVKRTKVKWLIIPAIIGGSALLADGIITPPVSVASAVEGVRTYYPDINTVPIVIAILVVLFTIQQFGTKLVGKFFAPMMMIWFAMLAILGILQITQNTSVLCAVNPYYAYKLLSIHPDGFYVLGFVFLCTTGAEALYSDMGHCGRKNIRISWIFVKIALLLNYFGQGAYLIKHAGHTLKSINANNGNPFYLVMPEWFQPFGIVISTMAAVIASQALISGSFTLINEAMRLNFWPKVKIKYPTDLKGQIYIPSINWLLLAGCIGIVLHFEESSKMEAAYGLAIVLCMIMTTILLTYFMILKRISWFIIAPLILLYLVIEFSFLIANLDKFPHGGYVTLIIASALTFIMSIWYTAKKISKNYTKIVKIQTYKKVLAELSVDLSIPKYATHLVYMTNANRVDEIEEKVMYSILQKRPKRADLYWFIHINITNEPYKKEYKVTEIIKNDLFRIDFNLGFREPTKINLMFKEVIKDMVAKGEVDITSRYESLSKNNIIGDFKFVLSEKFLSNDSFMHWHEKLVMNTYFFFKKMSLSEEQAFGLDSSSVKVEKFPMVLHAPEKIELCRIK
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DCNL3_RAT
Sequence: MGQCVTKCKNPSSTLGSKNGDRDPSSKSHSRRGASHREEQVPPCGKPAGDILVNGTKKAEAATEACQLPTSSGDAGRESKTNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREVEGRGALSSGPEGLCPEEQT
What is the function of this protein?
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and may play a role in the cell cycle progression by regulating the SCF ubiquitin E3 ligase complex, after UV damage.  At the cell membrane, can promote and as well inhibit cullins neddylation.
What are the official names of this protein?
DCN1-like protein 3, DCNL3, DCUN1 domain-containing protein 3, Defective in cullin neddylation protein 1-like protein 3.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=After UVC treatment, the protein enters to the nucleus gradually. Cell membrane localization is essential for CUL3 neddylation.
Protein: PATR_RHOE4
Sequence: MTAHIRPDLASIPAYVPGRNFPGAIKLASNETTVGPLPGVRDAVADAVANANRYPDNAAVALIEALASFLKVEPANVAAGCGSVTLCQELVQITCDQGDEVIYAWRSFEAYPVVTQVGHAVSVKVPLTEDFGHDLDAMLAAITDRTRLIFVCNPNNPTGNALSKAELESFLDAVPAHVVVALDEAYFEYSRSDADGIELFRSRPNVVVLRTFSKAYGLAGIRVGYAVADPEIIVALGKVHTPFTVSAVAQAAAIASLAAADELLARTEGVIAERTRVRTALIEAGYTVPESSANFVYLPLGELSPAFAEASTEAGILIRQYGVEGVRMTIGDPHENDAFLAFADTDVAKQAAGIGVSA
What is the function of this protein?
May catalyze the transamination reaction in phenylalanine biosynthesis.
What are the official names of this protein?
Putative phenylalanine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: CPGS_METST
Sequence: MKSKNSMSVLCLVDGEHYFPVTKSAVDKIESKGYDVKLLLFIGGTEKLRDTNVDIISEMFNKPVLFGQDHSKVPYDLIEESIKEYDVGMVVDLSDEPVVNYSIRFNIATIALLNGCMYKGSDFEFKALEEEDVLNNPSYKIIGTGKRIGKTAVSAYTARLINKDSDFVPCVVAMGRGGPQIPEIVRGDKIHLTPKYLMEKSDKGFHAASDHWEDALMSRVLTVGCRRCAGGMAGMVYETNMVEGAMMTNDLDVNLVALEGSGSAIPPVKADKQIVLVGGHQPMETLTEYFGPYRIKLADLIIITMCDEQICSREKLDDLLIKIHEINPNADIVPTIFRPHPVDDISNKNILFATTAPESVQHLLKDYLEENFNCNVVAISSHLSNRPLLQRDIEENIDNIDCMLTELKAAAVDVATKDALNKGLEVVYCDNIPIAINDEYDLDKSIMNIVYEAKESFNKKD
What is the function of this protein?
Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP.
What are the official names of this protein?
Cyclic 2,3-diphosphoglycerate synthetase, cDPGS.
What is the protein family that this protein belongs to?
Belongs to the cyclic 2,3-diphosphoglycerate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_SYNP2
Sequence: MSNSINPIVWQEDCVLLVDQTLLPLAYKVVEIKTYQAMAEAIRTMIVRGAPAIGVSAAYGLYLGAKEIQTTDRTIFLEKLEAIAATLRQTRPTAVNLFWAIDRVMATVQGATGNIPELQNLILNTAKAIHNEDLATCQAIGDQGLAVLPETPEKLTILTHCNAGGLATAGYGTALGVIRSAWRENRLGMVYADETRPRLQGSKLTTWECVQEGIPVTQICDNMAAHCMQQGRIDAVVVGADRITANGDAANKIGTYSLAIVAKAHNVPFFVAAPLSTVDFSLSDGKQIPIEERDPKEVYQIGDTRICPEGVQFYNPAFDVTPAHLITAIITEKGAVAPDQLIHLKG
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: CH10_EXISA
Sequence: MLKPLGDRVIIEVVEKEEKTIGGIVLPDTAKEKPQQGKVVAVGTGRVTDEGKRIDLDVKENDLVIYSKYAGTEVKHDGKEYLIVRESDILAIVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.