PharMolix/UniProtQA huggingface dataset:
Protein: CTDS1_MOUSE
Sequence: MDSSAVITQISKEEARGPLRGKGDQKSAVSQKPRSRGILHSLFCCVCRDDGEPLPAHSGAPLLVEENGAIPKHTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS
What is the function of this protein?
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.  Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity).  Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
What are the official names of this protein?
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, Golli-interacting protein, GIP, Nuclear LIM interactor-interacting factor 3, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: O162_CONIM
Sequence: MKLTCMMIVAVMFLTASIFITADNSRNGIENLPRMRRHEMKKPKASKLNKRVCIADDMPCGFGLFGGPLCCSGWCLFVCL
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like 2/7.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: STIMA_MOUSE
Sequence: MQGPGGNVSRGLPSGPASTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVGVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNAFMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDAEEDLRRPVKKKHRFGLPV
What is the function of this protein?
Acts as a regulator of store-operated Ca(2+) entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER.  SOCE is a Ca(2+) influx following depletion of intracellular Ca(2+) stores.  Acts by interacting with STIM1, promoting STIM1 conformational switch.  Involved in STIM1 relocalization to ER-PM junctions.  Contributes to the maintenance and reorganization of store-dependent ER-PM junctions.
What are the official names of this protein?
Store-operated calcium entry regulator STIMATE, STIM-activating enhancer encoded by TMEM110, Transmembrane protein 110.
What is the protein family that this protein belongs to?
Belongs to the STIMATE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with STIM1 at ER- plasma membrane (ER-PM) junctions, also called cortical endoplasmic reticulum (ER), in store-depleted calcium cells. May translocate to ER- PM junctions in a STIM1-dependent manner in store-depleted cells.
Protein: RDGC_NEIG1
Sequence: MWFKQISFYPLNKEKLPEADVLADKLAEAEFTHCQGLDWFSEGFTAPVSFSPELVFPADFTLRVALKKEEKVLPAGVIRDILEEKVAEIQNNEARNVGRKEKQELKEQITDDLLPRAFTRSSRTEAVFNTRHGYLLVNNAASAKAENILTKLREALGGLEASLPNTKQSPSSLMTGWLLQGHCEGGFELDSDCELKGTGDIVPVVKVSKQDLTADEVVQHVKNGKTVTRLGLVWREQIAFILTQDFTLKRIQYLDVLQEEAESNGDDAAGLAFASQILMAESVSTMLEELVSYLGGWQD
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DNAB_RICTY
Sequence: MVRNKINNNINIITNNDDNLSIPRVLPSNIQAEQMLLGAIITNNELLSYVSEFLRNEHFFEPIHQKIYDAIEKIIEKGLIATPITLRSMLTQDALFQEIEGVEYLAKLITMSMMVINPIDYGKIIYDLAIKRNLINIGEEVVNNAYNASLAVAAKEQIEHAEAKLYDLAREGLNEKSFTQVGISIAESLASINKAMKNNDHVIGISTGLLDLDNKLFGFHNSDLIILAGRPSMGKTAFAINLALNTCNNMRLKNIRDNQEIKSVGFFSLEMSSEQLTTRLLSLCAEIDSTSLRTGMLSEEKYNRLRKEANTLSELQFFIDDTPALSISAIRTRARRMKRKHNLGILFIDYLQLIRGVSKSENRVNEISEITQGLKAIAKELNIPVIALSQLSRAVELREDKKPMLSDLRESGTIEQDADIVMFIYREEYYLTRKEPAAGDAKHAEWLDKLNKVYNIADIIIAKHRNGPVGNISLYYDSQFSKFGNLEKRTFNSILNT
What is the function of this protein?
Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.
What are the official names of this protein?
Replicative DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. DnaB subfamily.
Protein: DNAK_CYACA
Sequence: MEKIVGIDLGTTNSVIAVMEMGKPAVIPNSEGFRTTPSVVAYAKNGDLLVGQIAKRQAVINPSNTFYSVKRFIGRKFEEINEENRQVTYQVNKDPSGNVKIYCPFKNKDFTPEEISAQVIRKLTEGASKYLGEKITKAVITVPAYFNDSQRQATKDAGKIAGLDVLRIINEPTAASLAYGLDKKNNEKILVFDLGGGTFDVTILEIGDGIFEVLSTSGDTHLGGDDFDKKIVDWLVDEFKKSYNIDLSKDKQALQRLTEAAEKAKIELSSVSQTEINLPFITATSEGPIHFDKSLNRAKFEELVSELIARCKIPVENALKDAKLNKSDINEIVLVGGSTRIPAIQNLVKESLQKDPNQTVNPDEVVAVGAAIQGAVLAGEVKDILLLDVCPLSLGVETLGGVMTKMIPKNTTIPTRKTEIYSTAVDNQTNVEIHVLQGERELAKDNKSLGTFRLDGIPPAPRGVPQIEVTFDIDANGILSVTAKEKTTGKQQSVTITGASTLDKDEIQKIIKEAEINAQEDRKKKENIELKNQAETICYQAQKQLNEFKEKIDKNQYKRIEDLIAKLKQAISSNEYEEIKNLMEAIQKETMEIGKELYSKDSKNTKNSDVIDADFSET
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LAP2_RAT
Sequence: MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLAAGANSKGPPDFSSDEEREPTPVLGSGASVGRGRGAVGRKATKKTDKPRPEDKDDLDVTELSNEELLEQLVRYGVNPGPIVGTTRKLYEKKLLKLREQGAESRSSTPLPTVSSSAENTRQNGSNDSDRYSDNDEDSKIELKLEKREPLKGRAKTPVTLKQRRIEHNQSYSEAGVTETEWTSGSSKGGPLQALTRESTRGSRRTPRRRVEPSQHFRVDGAVISESTPIAETIKASSNDSLVANRLTGNFKHASSILPITEFSDITRRTPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSVPMWIKMLLFALVAGFLFLVYQAMETNQGNPFTNFLQDTKISN
What is the function of this protein?
Binds directly to lamin B1 and chromosomes in a mitotic phosphorylation-regulated manner.  May play an important role in nuclear envelope reassembly at the end of mitosis and/or anchoring of the nuclear lamina and interphase chromosomes to the nuclear envelope.
What are the official names of this protein?
Lamina-associated polypeptide 2, isoform beta, Thymopoietin isoform beta, TP beta.
What is the protein family that this protein belongs to?
Belongs to the LEM family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass type II membrane protein. Chromosome. Note=Tightly associated with the nuclear lamina.
Protein: SUFS_SALTY
Sequence: MTFPVEKVRADFPILQREVNGLPLAYLDSAASAQKPNQVIDAESAFYRHGYAAVHRGIHTLSAQATESMENVRKQASRFINARSAEELVFVRGTTEGINLVANSWGTENIRAGDNIIISEMEHHANIVPWQMLCERKGAELRVIPLHPDGTLRLETLAALFDDRTRLLAITHVSNVLGTENPLPDMIALARQHGAKVLVDGAQAVMHHAVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMISTVSLTQGTTWAKAPWRFEAGTPNTGGIIGLGAAIDYVTSLGLDKIGDYEQMLMRYALEQLAQVPDITLYGPAQRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAWYGVPAMCRASLAMYNTHEEVDRLVAGLTRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTPB1_HUMAN
Sequence: MATERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDSDCSEDGEALNGEPELDLTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSDGTEYGLSEADMEASYATVKSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVGAPPPGDEASSVGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQGACVTPASGC
What is the function of this protein?
Promotes degradation of target mRNA species.  Plays a role in the regulation of circadian mRNA stability.  Binds GTP and has GTPase activity (By similarity).
What are the official names of this protein?
GTP-binding protein 1, G-protein 1, GP-1, GP1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. GTPBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_BUCAT
Sequence: MLNPNIFHMPKIIIALDFCNKKSAMKLVNLLNPSIFYLKIGKEMFTILGCKFVKELHQLGFNIFLDLKFHDIPNTVFNATKAAADLGIWMLSVHASGGKEMLISAKKALKSFKKAPLLIAVTALTSFKEEALKEIGINISLTEYILKLSKLSNDCGLDGIVCPGKEAKKIKFLFGNKYKIITPGIRIAKDLLYDQNNIITPKEAKEYKIDYIVIGRSITMSKNPIKKLDLIIKSMQ
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: EHD4_MOUSE
Sequence: MFSWMGRQAGGRERSGGMDAVQTVTGGLRSLYQRKVLPLEEAYRFHEFHSPALEDADFENKPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISIIDSPGILSGEKQRISRGYDFCQVLQWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDLIKRARLAKVHAYIISYLKKEMPNMFGKENKKRELIYRLPEIYVQLQREYQISAGDFPEVKAMQEQLENYDFTKFHSLKPKLIEAVDNMLTNKISSLMGLISQEEMNMPTQMVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPNSLPPHLVPPSHRKSLPKAD
What is the function of this protein?
ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis.  Plays a role in early endosomal transport.
What are the official names of this protein?
EH domain-containing protein 4, PAST homolog 2, mPAST2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. EHD subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UXAC_NOSP7
Sequence: MLTKKPVLSPDRCFSPEPVQRRLAHQFFDSISALPLVCPHGHVDPALLANPAARFGSPTELFIIPDHYILRMLYSRGVPLEALGIPTRDAPTETDHRKIWQLFAEHFYLFQGTPSGLWLKDELTNVFGVDEALNSRNAGRIYDYLEGLLALPKFSPRALFKRFNIEVLCTTDAASDNLENQRSLHEEGFTQIRPTFRPDAVVNLDAPGWRENLTKLESSIGREISSYATFVQALEERRAFFKKMGATATDQGAATPYTTSLSDQEAEAIFARALIGKLNPGDVEQFTGHIFMEMARMSVEDGLVMQMHCGVMRNHNPALFERFGSDKGADIPLNIEWTRNLHPLLSSYGNNQRFRLIIFGMDESTYSREMAPLAGHYPTILLGPPWWFHDSVNGMERYFNQVMETAGIYNTAGFNDDTRAFVSIPARHNVWRRVACNWLAGLVTRGLVDEEEGYDMARALAYDLAKSAYKLD
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: YGFZ_YERPG
Sequence: MAYHTPFAAQPPVASSGLPLTLISLDDWALVTLTGADRVKYLQGQVTADIDALSADQHVLCAHCDAKGKMWSNLRLFYRGEGLAFIERRSLLDNQLSELKKYAVFSKVVIEPQPDAVLIGVAGSQAKTALAEIFTELPSAEHPVTQMGNSTLLHFSLPAERFLLVTDTEQAQQLVEKLAGRAQFNDSKQWLALDIEAGFPIIDAANSAQFIPQATNIQALNGISFTKGCYTGQEMVARAKYRGANKRALYWLAGNASRVPAAGEDLEWQLGENWRRTGTVLSAIQLNDGTVWVQAVLNNDLAADSVLRVRDDALGTLAIQPLPYSLAEDK
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRQ_TRISN
Sequence: MQPTEDLPRGTPLSSTGHPLPRRTSPEQSVTLRHHQLARDASLKASLGSAPPNDSNENSSSPRRASSGESHETGQSDAKKWFNQSNQNPTATFDSNAMDVDPPFFQKESDSSNEDKPYQFPPATIRIQSNARSSSADDYRSVIDDLTVEIQKLKEELKRYKQRGPDMLRKDKLFEIKIHGLPKRKKRELEATLREFTATLEGSPNTSSSKRNSTTKPSRHATRDRMYSGSGSKSQSKHASSSSGSHTRPVDSAYASMSTGAGSSGTSLNRPQGGSRFKTNEQKVDHYLREIPEGLYPRFVSMTEKEKKKLVVRRLEQIFTGKIGGKHVRRTQPTLTPAVSIALPAVQATSIDFSPQQQQQQQQQQQQQPKSNFITNPGATFSSVPEPLREARILPQEHQYGHVAGQKGRSHDIGSASNSNEDQTESGGNGNSSSNGNDSGTNPSPPMPPPPEQRPTRPRDLDPDRIQIPSENMEYIRHLGLVPPELLTNPPERTSFDFHPDEEGWVYLNLLCNMAQLHIMSVTPDFVRNAVVDLSAKFQLSPDGRKIRWRGGTDGTKFSSESSGDLSQRSPETDDTENTKGDNHKRQKTGHSTGDSGSSGNNLPKFGGPQVSASSESFHYKPLFLHQQSPNEQSSMEDGTLSSFGPIEESNADSRWGQSGSGASNRRKRRRDGAIIYYSGAPFCTDLSGDPGDTSPATYMLSSERERPDAQGQFARPLPFRSGSGSSITRRPLSDAHLNLGSIPKLQLLNEGVSIPELVTDSGDESSKLSMEFPWSDEPQILEVRPLEPCGLGGVRPEDHFMVVVTTRRSKLDARVGQRLEGQRKLSEEMTDIVVNRLATMSTSSPRPSVRRLSNMSDSSKIKIEYLSGRIKRLEPVSLPPPAIFFPPFSADSCSEDDFGSDGDDEFNSSEEFMSRRANPHQSDDYPDGVDLSSGDEDGEEPEDDIDASRMVDDMSLPGLGRVPRGSQASTEVVPGSSRGRSNSASAEAVLRAGGSSAATAGGVESDFSISSSQG
What is the function of this protein?
Circadian clock component involved in the generation of biological rhythms, in particular in rhythm stability, period length, and temperature compensation.  Behaves as a negative element in circadian transcriptional loop (By similarity).
What are the official names of this protein?
Frequency clock protein.
What is the protein family that this protein belongs to?
Belongs to the FRQ family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SIDT1_HUMAN
Sequence: MRGCLRLALLCALPWLLLAASPGHPAKSPRQPPAPRRDPFDAARGADFDHVYSGVVNLSTENIYSFNYTSQPDQVTAVRVYVNSSSENLNYPVLVVVRQQKEVLSWQVPLLFQGLYQRSYNYQEVSRTLCPSEATNETGPLQQLIFVDVASMAPLGAQYKLLVTKLKHFQLRTNVAFHFTASPSQPQYFLYKFPKDVDSVIIKVVSEMAYPCSVVSVQNIMCPVYDLDHNVEFNGVYQSMTKKAAITLQKKDFPGEQFFVVFVIKPEDYACGGSFFIQEKENQTWNLQRKKNLEVTIVPSIKESVYVKSSLFSVFIFLSFYLGCLLVGFVHYLRFQRKSIDGSFGSNDGSGNMVASHPIAASTPEGSNYGTIDESSSSPGRQMSSSDGGPPGQSDTDSSVEESDFDTMPDIESDKNIIRTKMFLYLSDLSRKDRRIVSKKYKIYFWNIITIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLLGFLFLLIVLRRDILHRRALEAKDIFAVEYGIPKHFGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGLCMLKLYQTRHPDINASAYSAYASFAVVIMVTVLGVVFGKNDVWFWVIFSAIHVLASLALSTQIYYMGRFKIDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGNLVNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIVATAVMWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSATALFFSFLVLLTLDDDLDVVRRDQIPVF
What is the function of this protein?
In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp.  Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded.
What are the official names of this protein?
SID1 transmembrane family member 1.
What is the protein family that this protein belongs to?
Belongs to the SID1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL11_AFIC5
Sequence: MAKKVTGYLKLQVPAGAANPSPPIGPALGQRGLNIMEFCKAFNAQTQKIEKNTPIPVVITIYADRSFTFEMKTPPMSFFLKQAAKVQSGSKTPGRDSAGKVTKAQVREIAEKKMKDLNCDTVEAAMKMVEGSARSMGLEVAG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: ASL5_SARSH
Sequence: MSAIQRLTGKTAVITGGATGIGFAAAKRFIEEGAFVFIFGRRQEKLDAATAALGPNSRAVQGSVTELADLDRLYEAVKAERGSLDIVMANAGAGMATPLGKITGEQCDIVFGTNLKGTIFTIQGALPLMAQAGGGSIILTGSSSGTTGAPPLSVYGASKAAIRNLARSWAGTLRDEGIRINVLSPASIATEIAKEALGEQGMKMFAQQNPLKRMGQPEEVGAVAAFLASSDSSFMTASEVSVDGGLAQI
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of xenovulene A, an unusual meroterpenoid that has potent inhibitory effects on the human gamma-aminobutyrate A (GABAA) benzodiazepine receptor (PubMed:29773797).  The first step of xenovulene A biosynthesis is the biosynthesis of 3-methylorcinaldehyde performed by the non-reducing polyketide synthase aspks1 (PubMed:17912413, PubMed:29773797, PubMed:20552126).  The salicylate hydroxylase asL1 then catalyzes the oxidative dearomatization of 3-methylorcinaldehyde to yield a dearomatized hydroxycyclohexadione (PubMed:29773797).  The 2-oxoglutarate-dependent dioxygenase asL3 further catalyzes the oxidative ring expansion to provide the first tropolone metabolite (PubMed:29773797).  The cytochrome P450 monooxygenase asR2 allows the synthesis of tropolone hemiacetal (PubMed:29773797).  In parallel, a previously unrecognised class of terpene cyclase, asR6, produces alpha-humulene from farnesylpyrophosphate (FPP) (PubMed:29773797).  The putative Diels-Alderase asR5 probably catalyzes the formation of the tropolone-humulene skeleton by linking humulene and the polyketide moiety (PubMed:29773797).  Oxidative-ring contractions catalyzed by asL4 and asL6 then processively remove carbon atoms from the polyketide to yield xenovulene A (PubMed:29773797).
What are the official names of this protein?
Oxidoreductase asL5, Xenovulene A biosynthesis cluster protein L5.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RS5_PYRFU
Sequence: MSQEWKEYAKRVLDEWEPKTKLGMMVKEGQITDIHEIFRRGYQIKEPEIIDVLLPEVNARENQEVLDIALTVRMTDSGRRVRFRVLAAVGNRDGYVGLGIGHGKEVGIAIRKAINYAKLNIIEIKRGCGSWECRCRRPHSVPFAVEGKEGSVRVRLIPGPRGLGLVIGDVGKKILRLAGVQDVWSQTFGETRTTVNFAKAVFNALYNTNRVAISPEMIERYGIVVGRAMPTTFTLE
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5, PfS5, Small ribosomal subunit protein uS5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: T2R46_PANTR
Sequence: MITFLPIIFSILIVVTFVIGNFANGFIALANSIEWFKRQKISFADQILTALAVSRVGLLWVLLLNWYATELNPAFYSIEVRITAYNLWAVINHFSNWLATSLSIFYLLKIANFSNLIFLCLKRRVKSVVLVILLGPLLFLVCHLFVINMNQIIWTKEYEGNMTWKIKLRSAMYLSNTTVTILANLVPFTLTLISFLLLICSLCKHLEKMQLHGKGSQDPSMKVHIKALQTVTSFLLLCAIYFLSIIMSVWSFESLENKPVFMFCEAITFSYPSTHPFILIWGNKKLKQTFLSVLWHVRYWVKGEKPSXP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).  In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 46, T2R46.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
Protein: COXX_SYNP2
Sequence: MLGTSLSPHHENFWAVIKSYYQLTKPRIIPLLLITTAASMWIASHGHIDPVKLLITLLGGTLAAASAQTLNCIYDQDIDFSMQRTRKRPIPSGRVQPRHALIFALILGSLSFSLLMVFVNLLSACLALSGIVFYMLVYTHWLKRHHVQNIVIGGAAGSIPPLVGWAAVTGQLDWSAWILFALIFLWTPPHFWALALMIKEDYAEVEVPMLPVVKGEKITVDQIWIYTLIVVPFSLLLVFPFQASGLFYAIAALVLGAIFIQKAWELKQNPFDQSLAKSMFKYSILYMMLLCTAMVVDSLPAVHDVTALVTTTLASLT
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPF_LACE2
Sequence: MRVGMGYDVHKLVKDRKLIMGGVEIPYELGLLGHSDADVLLHAIMDALLGAAALGDIGKHFPDTDDRYKGISSIKLLEEVGKKIDEANYIIENIDATIIAQKPKMRPYIDDMRKNIADALKIDVDRVNVKATTEEGLGFTGSGEGISSQAICSLNSVSNYIYGAADMTNCRSDCGGCMGCQNK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SYE_LEPBA
Sequence: MTEVRTRFAPSPSGFLHVGGARTALFNYLYAKAKKGKFLLRIEDTDQDRSTEASFKIILESLKWLGMEWDEGPGVGGPNGPYTQSERIHIYKEYTDKLIQEKKAYRCFCTAEELEGKKKQADAMGIPYIYDGKCSDLSDAEIGSQLEKKIPFTVRFKTPHKIVIVDDMIQGKVKFESKLIGDFIIVKSDGFPSYNYAVVIDDALMKITHVIRGVGHLSNTPRQILIFEAFGFPLPRFAHASEIVGTDGKKLSKRAGATSVLAFRDLGYSSETMRNYMALLGWTSPDGKEYMSDEELCSVFDVERCSKSPATFDVFKKLKEEEKESVDFNKLTILGLAEYLNPKSKLNWMSNKYIRDTKIETLGKALEPFLKDCQIPEAFKSGENPQLLSILDSVRVYLDRLIQAPPYIEEFFLENLSFENDEAKQLVLEGKGKEVVAEFYRIVKESSLTTPDAYKESMAKVGEITGEKGRTLFMPIRAITTGKSHGLELPILFSLLGQEKMVKRMEQLAGILGISLR
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.