PharMolix/UniProtQA huggingface dataset:
Protein: RP07_MYXVL
Sequence: MVFQLVCSTCGRDISEERYALLIKKIDLKTVLRGVKNNCCRLKLSTQIEPQRNLTVEPLLDIN
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase 7 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 7 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: RL22_GADMO
Sequence: MAPVKKQGGKKKKQILKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKSGNLGNGVVSIERXXSKISVNSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANTKESYELRYFQINQDEEEIHMTS
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL22 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCS_CALS4
Sequence: MWADIYHKLVEIYDIKAVKFLLDVLKILIIAFIGIKFADFLIYRFYKLYSKSKIQLPQRKIDTLTSLTKNAVRYIIYFLAGASILKLFNIDMTSLLAVAGIGSLAIGFGAQNLVKDMISGFFIIFEDQFSVGDYVTINGISGTVEEIGLRVTKIRGFSDGLHIIPNGEIKMVTNLTKDSMMAVVNIAFPIDEDVDKIIEGLQEICEEVKKSRDDLIEGPTVLGITDMQDSKLVIMVYAKTQPMQKWAVERDIRYRVKKMFDQKNISFPYPRTTVILSEKKTN
What is the function of this protein?
Mechanosensitive ion channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins.  Has high selectivity for anions, and may contribute to resistance to hypoosmotic shock.
What are the official names of this protein?
Small-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VL2_HPV23
Sequence: MVRAQRTKRASVTDIYKGCKASGTCPPDVLNKVEQNTLADKILKYGSVGVFFGGLGIGTGKGTGGATGYVPLRPGVRVGGTPTVVRPAVIPEIIGPTELIPVDSIAPIDPEAPSIVSLTDSGAAADLFPSEAETIAEVHPTPVDIGIDTPIVAGGRDAILEVVDTNPPTRFSVTRTQYDNPSFQIISESTPITGEASLADHVFVFEGSGGQHVGAVTEEIELDTYPSRYSFEIEEATPPRRTSTPIERISQEFRNLRRALYNRRLTEQVQVKNPLFLTTPSKLVRFQFDNPVFDEEVTQIFERDVAEVEEPPDRDFLDIDRLGRPLLTESTEGRIRLSRLGQRASIQTRSGTRVGSRVHFYTDLSTINTEEPIELELLGEHSGDASVIEEPLQSTVIDMNLDDVEAIQDTIDTADDYNSADLLLDNAIEEFNNSQLVFGTSDRSSSAYSIPRFESPRETIVYVQDIEGNQVIYPGPTERPTIIFPLPSAPAVVIHTLDKSFDYYLHPSLRKKRRKRKYL
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: METK_THEMA
Sequence: MRRLFTSESVTEGHPDKIADQISDAILDAMLEQDPRSRVAVETLVTTGLVIIAGEVTTRAYVEIPDIARKTILEIGYTRAKYGFDGETCGVLTSIHSQSPDIALGVDKALEVKTGEEVADEFEALGAGDQGIMFGYATNETPEYMPLPITLAHKLAMRLAEVRKNGTLPFLRPDGKTQVTIEYEDDKPVRVDTVLISTQHDPDISQADLREAIIEHVINPVIPEQYRDDKMKILVNPTGRFVLGGPMADTGLTGRKIIVDTYGGWVPHGGGAFSGKDPTKVDRSAHYMARYVAKNVVAAGLADKFLIQLSYAIGVAKPVSIMIDTYGTAKVDEDKLLKVITELFDFRPGAIIKKLNLLRPIYRKTAAYGHFGRNEEEFTWEKLDMVDELKRAFNM
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_CORGL
Sequence: MTAIKLDGNLYRGEIFADLEQRVAALKEKGIVPGLATVLVGDDPASHSYVKMKHRDCEQIGVNSIRKDLPADVTQEELFAVIDELNNDDSCTGYIVQLPLPKHLDENAVLERIDPAKDADGLHPVNLGKLVLNEPAPLPCTPNGSISLLRRFGVELDGAKVVVIGRGVTVGRPIGLMLTRRSENSTVTLCHTGTKDLAAETRAADVIIAAAGQPHMLTADMVKPGAAVLDVGVSRKDGKLLGDVHPDVWEVAGAVSPNPGGVGPLTRAFLVHNVVERAEKLAGL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PYRC_DESPS
Sequence: MIIILKGGRVIDPRNRRDEDADIWMEDGQIIAPQETVPEDAKIYDLAGKWVVPGLIDMHVHLRDPGEEYKESIVTGTDAAAAGGFTAVACMPNTDPVNDTGSVTRYILEKSEGAAARVYPVGALSEGLKGESLAEYADMKHAGAVALTDDGNPVVSSQLMRRAMEYAKSHDMLVISHSEEPTLSKRGCMNEGLVATRLGLKGIPAVAESIMVQREIALAGLTGARLHIAHVSCIESLAAIRDAKKRGLPVTAETAPHYFSLTDDAVIGYDTHAKMNPPLRTEEHRQAIRQALADGTLDVIATDHAPHSIVEKEVTFEYAANGIVGLETSLGLSLALVRDGVLTPSRLVELMSSVPAQILSVAGGELGVGAIADVTVIDPELEHTFLIAEGRSRGANSPFDGWKLKGAATLTFVAGEESYCR
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: IF4A_NEOFI
Sequence: MASNDKGLEEIPEGQIESNYDEITDSFDSMELKPELLRGIYAYGFERPSAIQQRAILPIIKGNDVIAQAQSGTGKTATFSISALQKLDPNVKGCQALILAPTRELAQQIQKVVVAIGDFMNIECHACIGGTNVREDMKALQEGPQVVVGTPGRVQDMIQRRVLRTDNLKMFILDEADEMLSRGFTEQIYDIFQLLPQSTQVVLLSATMPQDVLEVTTKFMRDPVRILVKKQELTLEGIKQFYIAVEKEEWKLDTLSDLYETVTITQAVIFCNTRRKVDWLTDKLTARDFTVSAMHGDMEQAQRDVIMKEFRSGSSRVLIATDLLARGIDVQQVSLVINYDLPANRENYIHRIGRGGRFGRKGVAINFVTADDVRMMREIEQFYSTQIEEMPMNVADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase eIF4A, Eukaryotic initiation factor 4A, eIF-4A, Translation initiation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_CHLCH
Sequence: MNQLIQLVESSLGANRFEQVRPGDTVKIQLRVIEGEKERLQAFEGVVISDRGEGGSKTITVRKISHGVGVERIIPVNSPNIESVTVLRHGRARRAKLFYLRKRTGKAALKVKERKTQVNA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RNFA_VIBVY
Sequence: MTEYILLLIGTVLVNNFVLVKFLGLCPFMGVSKKLETAIGMGLATTFVLTMASVCAYLVESYILEPLHIEYLRTMSFILVIAVVVQFTEMVVHKTSPTLYRLLGIFLPLITTNCAVLGVALLNINENHSFVESIIYGFGAAVGFSLVLILFASMRERISAADVPAPFKGASIAMITAGLMSLAFMGFTGLVK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YI7H_SCHPO
Sequence: MSVPLRFSTPSSSPSASDNESVHDDGPTTELDTFNTTDVPRRVNTTKARQMRPKNTLKVAFSSPNLKGLDNTADSDSQPWLGGYLAGRLEDISGQSRRNYVDPYYEELNAGRRPNKPVWSLNGPLPHVLGNSVVEKISQKNQEARSRANSRVNSRANSRANSSVSLAGMDGSPNWKRKMKSAVFGSRVKLNDEEAQLPRNKSSVSIAEQAASRPKVSFSLQSSRQPSIAEEQPQTQRKSSAITVEHAENAEPETPRNNVSFSRKPSIAEQDSSQDITMPPNEIIAEESLDSGSDTETLYLNYWCKIRHFFREGFAEFLGTLVLVVFGVGSNLQATVTNGAGGSFESLSFAWGFGCMLGVYIAGGISGGHVNPAVTISLAIFRKFPWYKVPIYIFFQIWGAFFGGALAYGYHWSSITEFEGGKDIRTPATGGCLYTNPKPYVTWRNAFFDEFIGTAVLVGCLFAILDDTNSPPTQGMTAFIVGLLIAAIGMALGYQTSFTLNPARDLGPRMFAWWIGYGPHSFHLYHWWWTWGAWGGTIGGGIAGGLIYDLVIFTGPESPLNYPDNGFIDKKVHQITAKFEKEEEVENLEKTDSPIENN
What are the official names of this protein?
Uncharacterized membrane protein C977.17.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GET3_COCP7
Sequence: MSSAALVPADDILEPTLQSILDQKSLRWIFVGGKGGVGKTTTSCSLAIQLAKVRKSVLLISTDPAHNLSDAFGQKFGKEARLVDGFDNLSAMEIDPSASMQDLLAAGGEQGEDMGFGLGGMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIVFDTAPTGHTLRFLQFPTVLEKGLAKLSQLSNQFGPMLNSVLGARGGLPGGQNLDEVLSKMESLRETISEVNAQFKDADLTTFVCVCIAEFLSLYETERMIQELTSYQIDTHAIVVNQLLFPGKDSTCEQCKARRKMQKKYLDEIAELYEDFNVVRMPLLVEEVRGKEKLER
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: ENV_OMVVS
Sequence: MASSKNMPSRITQKSMEPPLRETWQQVVQEMVMRKQRDEEEKQNLVTGKEKSWVSIDLLGTKQEGKRQKVNIWGPWEKWGIKIVWVMLWVIQLMLWGCLIWEMGKKHSCNAEEVIALVDDPGGFQKVKYVESVPVTCMTKNFTQWGCQPEGAYPDPDLEYRNISQDILEQVYKQEWPWNTYHWPLWQMENMRQWMKENEKEYTSRNNKTKEDIDALLAGKIRGRFCVPYPFALLKCEEWCWYPANINQETGHAQQIKINCTKAKAVSCTEQMPLAAVQRVYWEKEDEEGMKFMNIQACNESQLRCKTSPGGCVQGYPIPVGAEIIPESMKYLRGKKSPYGGIKDKNGELKLPLSVRVWVRMANLSGWVNGTPPYWSARIKGSTGINGTRWYGIGTLHHLGYNISSNPEKGLCNFTKELWIGGDRFQYQYKPSWNCSQNWTGYPVWHVFRYLDMTEHMTSRCVQRPLRHNITVGNGTITGNCSVTDWEGCNCTRSGNYLYNSTTGGLLVIICRQNSTITGIMGTNTNWTTMWGIYKNCSECKNSTLDRTDNGTLGTVNNINCSLPHYNESNKWTCAARNSKKKRDSLYIAGRDFWGRVKALYSCESNLGGLDGMMHQQMVLQKYQVIKVRAYTYGVVDMPKAYREKNMRNKRSTEISRPRKKRGIGLVIVLAIMAIIAAAGAGLGVANAVQQSYTRTAVQSLANATAAQQNVLEATYAMVQHVAKGVRILEARVARVEAIVDRMMLYHELDCWHYQHYCVTSTRTEVAQYVNWTRYKDNCTWQQWEEEIEQHEANLSLLLKEAALQVQIAQRDAQRIPDVWKALQEAFDWSGWFSWLKYIPWIVVCIVGVICFRLLMCVITMCLQAYRQVREIRYTRVTVVIEAPVDLEEKQREERDGSSGSENLEHEKRTSPRSFIQIWRATVQAWKTSPWGKGWKKILYMTLLPLLTLQIWMEETGWNGDKRCKKKKERVDCQDRESMPAIENEYVELS
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N- terminus of Gag (By similarity).
Protein: ACES_FELCA
Sequence: MRPPWCPLYTPSLAAPILLLLLFLLGGGAEAEDPELLVTVRGGQLRGVRLMAPGGPVSAFLGIPFAEPPVGPRRFLPPEPKRPWPGVLDATAFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLVWIYGGGFYSGASSLDVYDGRFLAQAEGTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQDNVATFGGDPMSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELVACLRTRPAQDLVDHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAQFLAGVRVGVPQASDLAAEAVVLHYTDWLNPEDPARLREAMSDVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLSWPLWMGVPHGYEIEFIFGLPLEPSLNYTAEERIFAQRLMRYWANFARTGDPNDPRDPKVPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL
What is the function of this protein?
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
What are the official names of this protein?
Acetylcholinesterase, AChE.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Synapse. Secreted. Cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Isoform H]: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side.
Protein: PDXB_ECO5E
Sequence: MKILVDENMPYARDLFSRLGEVIAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADCGDEGDFRSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL13_ARATH
Sequence: MKFSRENMKWVFPEIKTTQNFLSPSSLPQEPPLSLRSSANFDLNSKISPSILLIIIILSIIFFISGLLHLLVRFLLTPSSRDREDYFDNVTALQGQLQQLFHLHDSGVDQSFIDTLPVFHYKSIIGLKNYPFDCAVCLCEFETEDKLRLLPKCSHAFHMDCIDTWLLSHSTCPLCRSSLLSDLSSHQDPRSSFLLVLESASDHSSREIGGDRDSAACVAANDDIDVSSAHLGLVGNNDLGSTRIDSGHGDQYLDGELGGSVGKVVPFSVKLGKFRNIDIGEGTSSNNNIGNSSSLDERRCFSMGSYEYIMDEETTLKVHVSTKKQSSKNRGLPGHRTAMSECGFDPTGRLKFSGSGSMRIVEEAAEKNVVERESFSVSKIWLRGKKEKHSKVQGKEDSSLVSSSSGRAFSFRLSNQRNHPDAMIESGCEEDNQKCENSESLETKTPSFARRTMLWLAGRQNKVVHSSSSTNV
What are the official names of this protein?
RING-H2 finger protein ATL13, RING-type E3 ubiquitin transferase ATL13.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATS5_BOVIN
Sequence: HAAFTVAHEIGHLLGLSHDDSKFCEENFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQIPGPEELPGQTYDASQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPKNNGRYCTGK
What is the function of this protein?
Metalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration.  Extracellular matrix (ECM) degrading enzyme that shows proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including ACAN, VCAN, BCAN and NCAN.  Cleavage within the hyalectans occurs at Glu-Xaa recognition motifs.  Plays a role in embryonic development, including limb and cardiac morphogenesis, and skeletal muscle development through its VCAN remodeling properties.  Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration.  Participates in the development of brown adipose tissue and browning of white adipose tissue.  Plays an important role for T-lymphocyte migration from draining lymph nodes following viral infection.
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAM-TS 5, ADAM-TS5, ADAMTS-5, ADMP-2, Aggrecanase-2.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: YQGF_MYCA9
Sequence: MPDTAAPTPDRPGPDDPGRGRRLGVDVGTVRIGISSSDPDGILATPVETVSRDAKEDSDFRRIAELVEEMSVVEVVVGLPRNLREGTGSSARDAAGFARELGERIAPVPVRLVDERFTTTTAQRSLREAGVRSRQQRGIIDQAAAVAILQDWLEQRRRCGSEGDTP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUP42_XENLA
Sequence: MAICNFFLQGRCRYGEKCWNEHPRGGGGGGGNRYQSQNRYQEQSRYQEQSRYPEQSRYPEQNRYQEPAGNAKGTWGASSQRYVQPSNFSKSTTWINRDSEKPSAGSFSGFGSRNVKSTAATGLPSTQNRFAALSSQDNSRDGQTDKGNILDDIMKDMEIWESSGQWMFSVYSMLKEKKNISGFTDFSPEELRLEYSVCQAEGNPLKYINAVQQLGSKWKQRILELKNPNPSIKTALLNELNSPSPDVTPGYSGQQNSAFGALSFPTSNTAPTAVTFSFKADTTTAAKPAVPNALAGSDFSAFGNKPTSAPSFGSGVAAAAASFSFAPSTISGFGSTASNSGFGAASNAAGFQGAANIAAAPAFGVASSTAPASGFGGGFGTTVNTGAKTSSVRDLFSAGTAVPVQTTLLFGQATGSLNTTASSTSLAGQPFKASTSATAVSGSFTSDNTSNPLFTPRNELSVEDLAQFEAKQFTLGKTPIKPPSADLLKVT
What is the function of this protein?
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm.
What are the official names of this protein?
Nucleoporin NUP42, Nucleoporin-like protein 2.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GRDC_RHIS5
Sequence: MQGKVALEEHFAIPETLQDSAGFVPGDYWKELQHRLLDIQDTRLKLMDAHGIETMILSLNAPAVQAIPDRRKAIEIARRANDVLAEECAKRPDRFLAFAALPLQDPDAATEELQRCVNDLGFVGALVNGFSQEGDGQTPLYYDLPQYRPFWGEVEKLDVPFYLHPRNPLPQDSRIYDGHPWLLGPTWAFAQETAVHALRLMASGLFDEHPRLNIILGHMGEGLPYMMWRIDHRNAWVKLPPRYPAKRRFMDYFNENFHITTSGNFRTQTLIDAILEIGADRILFSTDWPFENIDHASDWFNATSIAEADRVKIGRTNARRLFKLDGA
What is the function of this protein?
Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (PubMed:15466039).  Catalyzes the reversible decarboxylation of gamma-resorcylate to resorcinol (PubMed:15466039).  The reaction is reversible, but equilibrium greatly favors the decarboxylation reaction (PubMed:15466039).  Also catalyzes the decarboxylation of 2,3-dihydroxybenzoate to catechol, but does not act on 2,4-dihydroxybenzoate, 2,5-dihydroxybenzoate, 3,4-dihydroxybenzoate, 3,5-dihydroxybenzoate, 2-hydroxybenzoate, or 3-hydroxybenzoate.  Only resorcinol is carboxylated by the reverse reaction (PubMed:15466039).
What are the official names of this protein?
Gamma-resorcylate decarboxylase, GRDC, Gamma-RDC, 2,6-dihydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
Protein: CB21_SOYBN
Sequence: ASPSTPQLGVGRVSMRKTASKTVSSGSPWYGPDRVKYLGPFSGEPPSYLTGEFPGDYGWDTAGLSADPETFAKNRELEVIHSRWAMLGALGCVFPELLARNGVKFGEASWFKAGSQIFSEGGLDYLGNQSLIHAQSILAIWATQVILMGAVEGYRIAGGPLGEVTDPIYPGGSFDPLALADDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLAEPVNNNAWAYATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein, chloroplastic, LHCII type I CAB, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: YCF66_MESVI
Sequence: MINIEFGPSTILGIAVVCGGILLYITRTIKPEISRDHDIFFSSVALLIGGILIFQGWRLDPILLFGQMLSTGTALCFIIESLKLRVPKENNKSLFSTQNKNNSNNRIIKFQPPSKYDINLNQRGKKEKKNNNFQLKENSKYTKDSLVPSNWNDINISSIDYEKPIDYQKK
What are the official names of this protein?
Uncharacterized protein ycf66, RF66.
What is the protein family that this protein belongs to?
Belongs to the ycf66 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.