PharMolix/UniProtQA huggingface dataset:
Protein: PO3F2_DANRE
Sequence: MATTASNHYNILTSSPSIVHSEPGSMQQATAYRDAQTLLQSDYSLQSNSHPLSHAHQWITALSHGEGGPWSSSPLGEQDIKPAVQSPRDEMHNSSNLQHQSRPPHLVHQTHGNHHDSRAWRTTTAAHIPSMATSNGQSLIYSQPSFSVNGLIPGSGQGIHHHSMRDAHEDHHSPHLSDHGHPPSQHQHQSHQSHHDHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSTSGSPTSLDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPAASEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGPLPGTEDVYGDTPPHHGVQTPVQ
What is the function of this protein?
Transcription factor that may play important roles in patterning the embryonic brain.
What are the official names of this protein?
POU domain, class 3, transcription factor 2, POU domain protein 47, ZP-47.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYA_DEIGD
Sequence: MTGPLTTAEIREKFLSFFESKGHLRLPSHSLIAPDPTTLFTVAGMQPFKPQFMGAPAKFPGYGENRRVTTAQKCIRVGDIENVGRTRRHLSLFEMMGNFSFGDYFKREAILWAWEFLTSPEWLGMDPARMYVTIYEDDNEAFGYWTQDVGLPEDHIHRFGADENFWPADAPAKGPNGPCGPCSEIYYDRGPHYGDDTWADYAQTRESARFLEVWNLVFPQYDRQDGGVLADLPFKNIDTGMGLERVASVVQDVPDFYSNDVFRPLVEKVAELSGKPYEGEVSVSHRVVAEHIRSVAMTIADGVALSNTGRGYVIRKILRRASRHAYLLGLHEPTLYRLVPLVVQAMGGAYPELVTEEARVTAAIRAEEERFLKTLESGMQRLSGLLEGMERGAVLPGEEAFLLYDTYGFPLDLTKEIAEEYGISVNEAEYAESLERAQETARAASKYGKSELFGGSQEALEGLPPTQFVGYDELEAQGEVLALVGAGERLDHLMAGSEATVVLSRTPFYAEGGGEVGDTGVLEWEGGRGLVRDTRKTPAGIWLHDVLVEEGELTPGVTVRGVVSSERQAIQRHHTATHLLHAALRAVLGPGVRQAGSLVAPERLRFDFTHGAALTADELGQVERLVSRWVTANFPVTWREMPLAEAKAAGATALFGEKYGDTVRVVRVEGGIPFGDATVTSMELCGGAHVTRTGDIGAFVIVSDENVAAGVRRIEALAGEAATAWVRAQLNNVHRVSGLLNTSPDTLETRVIGLQSQLRAAQQETAQARRQLAEAQMGGASTQQVRELGGFKVAVLRLSGIEGGELRGAADKLLDQSGADLAVIASDKGLVVKASKTAVARGAHAGQLIGKLAAAGGGKGGGRPDMAQAGIGNPEAALAALDTAF
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_FLAJ1
Sequence: MKIAIYGQYYQNSTEPIIKDIFAFFNSNNVEMVIEENFLNMLYEKQLVKKDYKTFPSNSALDNSFEMLISIGGDGTILRAAAFVRNSGVPLLGINAGRLGFLAKVQKENIDILLQYVINQNYTTSERTLLGLTCEPFNEAFKELNFAMNEVTVSRKDTTSMITVETYLNNEYLNSYWADGLIISTPTGSTGYSLSCGGPILTPDVKSLVITPIAPHNLTARPLVIPDDTEITLRVTGREDQYLVSLDSRISSVQNESVLKIKKTDYKIKMVEIPGETFLKTLRNKLLWGEDKRN
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP2_THEFY
Sequence: MPPTHNEFMRTDVPMQPMYEQTAQRLLRQRIVFLGQQVDDEIANRIVGELLLLSAEDRERDITLYINSPGGSVTAGMAIYDVMQYIPNDVRTVGIGLAASMGQMLLCAGTRGKRYALPHTRIMMHQPSGGIGGTASDIRILADQLLYVKKMFLERISLHTGQPVEQIEKDADRDRWFTAQEALEYGFIDEVLTNTPDVTGGRS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGD_CAMJE
Sequence: MDYKEQSHIIPTYKRFDIVLEKGQGVYLFDDKAKKYLDFSSGIGVCALGYNHAKFNAKIKAQVDKLLHTSNLYYNENIAAAAKNLAKASALERVFFTNSGTESIEGAMKTARKYAFNKGVKGGQFIAFKHSFHGRTLGALSLTANEKYQKPFKPLISGVKFAKYNDISSVEKLVNEKTCAIILESVQGEGGINPANKDFYKALRKLCDEKDILLIADEIQCGMGRSGKFFAYEHAQILPDIMTSAKALGCGLSVGAFVINQKVASNSLEAGDHGSTYGGNPLVCAGVNAVFEIFKEEKILENVNKLTPYLEQSLDELINEFDFCKKRKGLGFMQGLSLDKSVKVAKVIQKCQENALLLISCGENDLRFLPPLILQKEHIDEMSEKLRKALKSF
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA1_STAA1
Sequence: MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: PSD_HERAR
Sequence: MSNRLPVLPQYLLPKKALTIFAGKVAGAKAGRVTTGLIRWFIGKYGVNMTEAANPDIRSYASFNEFFTRALRSGARPLADDPYICPVDGAISQCGTIQKDQIFQAKGHSYSTTALVGGDHELAAQFDNGSFATVYLSPRDYHRIHMPCDGRLMRMIYVPGALFSVNPTTARGVPNLFARNERVVCVFEGAAGPFVLVLVGATIVGSMQTTWHGVVNATRNGNIREWHYDKQYLGLKKGEEMGRFLLGSTVVMLFPHDTLSFNPSWTAERPVRLGESMAQTVAAITPPAMQADVS
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: QSPP_SCHPO
Sequence: MSRVLQDAEFISLNSNDVKVNKGGCAAVATWIKEKLDSLGPQFAEWQNHELHPKTRDVSTLDWIFLVDILNFSFWSDVDVEDSGKHSKRFSIEYKGKLYTGYWSLCAAINKALDAGIPITSPAFYADEKQCPDTLIASVFDSATVEKIPLLEERIRIMRASGRVLVDSYHGSYCGLLKKCHNQAQRLIKLLLADFPDFRDVSVYKGRECYMLKRAQILVAETWACFQGQNYGRFDDIDSITMFADYRVPQILWQLGCLSYSSDFKKRLLKNELIAHNDPMEIEMRGCSIWAVEKILQNINRKDVNAITIDFFLWDLAKEWQAKGYKPSTQVDEVTIPCIRVRSIYY
What is the function of this protein?
Involved in salvaging queuosine.
What are the official names of this protein?
Queuosine salvage protein.
What is the protein family that this protein belongs to?
Belongs to the queuosine salvage protein family.
Protein: UREE_POLAQ
Sequence: MSEPIRVEKIIPKGQGLAKAVIARALELKLPFEIRNKSRFSETLSDGREAHFFLPRGNVLVDGDILVADDGSMIKVSAANQQVVTIASNDAHQLMKAAYHLGNRHIPTQLGKGFLRIEPDSVLEVMIRQLGLEAIHELAPFEPETGAYGGGHRHSHAETFDSDYALAQKVYAEHEKPHVHGPGCSHHHHGDHDHPHEH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_SULIY
Sequence: MPRPALRSRSLRRIYVKLPSGKTAIHYERKKNDISKCAMCKKPLHGVKTNFLHKYGKSEKRPERPFGGYLCSSCLAQLIKAMVRQ
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: RNC_STRPI
Sequence: MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNERLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKLGKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITDYKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQEAAKNAVEKGLDSCI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAFA_MYCTU
Sequence: MQRRIMGIETEFGVTCTFHGHRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDSLVQLVTHDRAGEWVLEDLLVDAEQRLADEGIGGDIYLFKNNTDSAGNSYGCHENYLIVRAGEFSRISDVLLPFLVTRQLICGAGKVLQTPKAATYCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAEKYRRLHVIVGDSNMSETTTMLKVGTAALVLEMIESGVAFRDFSLDNPIRAIREVSHDVTGRRPVRLAGGRQASALDIQREYYTRAVEHLQTREPNAQIEQVVDLWGRQLDAVESQDFAKVDTEIDWVIKRKLFQRYQDRYDMELSHPKIAQLDLAYHDIKRGRGIFDLLQRKGLAARVTTDEEIAEAVDQPPQTTRARLRGEFISAAQEAGRDFTVDWVHLKLNDQAQRTVLCKDPFRAVDERVKRLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.  PafA is required to confer resistance against the lethal effects of reactive nitrogen intermediates (RNI), antimicrobial molecules produced by activated macrophages and other cell types.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: IF2_SHEB8
Sequence: MADTTVEKLATEVGKSVERLIEQFSQAGIKKGQADNVTEAEKQQLLDYLKKQHGGENAPTKMTLQRKTVSTLSVAGNGGQSKDVKVEVRKTRTFVKRDANEATLKAEEEAKVEAEALAKAKAEAEAAAAVKAKAEADAKAKADAEAKAKAKAAAEVKVVKDMSPEAEAARLEAERLKAAQEAATKRKQDEEAAKAAETARLLAEEHSKRWAEEERQRLEAEKNGDHHITTSKVARAAEDTSDLDEEKRGRRARNKSNAKKRGGKDARDGREKHMRNRSTAPESMAHGFNKPVAAVSRDVRIGETVTVSELAHLMAVKATEIIKQMMKMGSMVTINQVLDQETAQMVAEEMGHKVVLIRENELEHQVLKDRDDEDGIKQESRAPVVTIMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTAMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAGNVPLIVAVNKMDKPEADIDRVKSELSQHGVMSEDWGGDNMFAFVSAKTGEGVDELLEGILLQAEVLELKAVRDGMAAGVVIESQLDKGRGPVATILVQEGTLRQGDIVLCGLEYGKIRAMKDENGRSITEAGPSIPVEILGLSGVPSAGDEATVVRDERKAREVALYRQGKFRDVKLARQQKSKLENMFANMTEGEVKELNIVLKADVQGSLEAITDSLTGLSTDEVKVNIIARGVGALTETDATLAAASNAILVGFNVRADAQARKTIDSESVDLRYYSVIYNLIDEVRAAMTGMLSPEFKQQIIGLAEVRDVFKSPKLGAIAGCMVTEGTIKRSAPIRVLRDNVVIYEGELESLRRFKDDVAEVRNGMECGIGVKNYNDVRVGDQIEVFETVEIARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_PSESM
Sequence: MPELPEVETTRRGIAPHLEGQRVSRVIVRDGRLRWPVPEDLDIRLSGQRIVQVSRRAKYLLIQAEVGTLISHLGMSGNLRLVEAGLAALKHEHVDIELESGLALRYTDPRRFGAMLWSHDPHNHELLIRLGPEPLTDLFDGERLYERSRGKSIAVKPFIMDNAVVVGVGNIYATEALFAAGIDPRREARGISRARYLKLAIEIKRILAYAIERGGTTLRDFIGGDGKPGYFQQELFAYGRGGQPCKVCGTTLREIKLGQRASVYCPKCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RFBV_SALTY
Sequence: MLISFCIPTYNRKEYLEELLNSINNQEKFNLDIEICISDNASTDGTEEMIDVWRNNYNFPIIYRRNSVNLGPDRNFLASVSLANGDYCWIFGSDDALAKDSLAILQTYLDSQADIYLCDRKETGCDLVEIRNPHRSWLRTDDELYVFNNNLDREIYLSRCLSIGGVFSYLSSLIVKKERWDAIDFDASYIGTSYPHVFIMMSVFNTPGCLLHYISKPLVICRGDNDSFEKKGKARRILIDFIAYLKLANDFYSKNISLKRAFENVLLKERPWLYTTLAMACYGNSDEKRDLSEFYAKLGCNKNMINTVLRFGKLAYAVKNITVLKNFTKRIIK
What is the function of this protein?
Catalyzes the transfer of CDP-abequose on D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid to yield D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.
What are the official names of this protein?
Abequosyltransferase RfbV, O antigen biosynthesis abequosyltransferase RfbV.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: ATPE_BURL3
Sequence: MATIKVDVVSAEEQIFSGEAKFVALPGETGELGILPGHTPLITRIRPGAVRIEVEGGNDEFVFVAGGILEVQPGAVTVLADTAIRGKDLDAAKAEEARKRAEETLQNAKSDLDLAKAQSELATAMAQLEAIQRLAKIRSRH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NOP9_COLGM
Sequence: MPKPRTKRQAIRDERKKKRRETHEETHEENHDERQSKRRRVDGEDRDEDEDTQQQTYNDAGDHPQPFHGNGPEKEFFGMLADEEQEYFRRADELLELNQFPSPEERHVFLQNVYKEARGKELKLASSQSLSRLMERLILLSNTRQKKQIFNAFAGHFLSLVQHRFASHCCEKLFLESAPIVTQELGGIVPETEGNYDEMEVEEDAEPDNTMENLFLMTLDEFEEHMGFLLTDRFGSHTLRVLLVILSGRPLDDSSTKLLLKSKKKEYISVQGATGASDELTHQLRAVPESFTQATKKIIQDAVAGMDFTALRVLAKHPTGNPLLQLLLELDISLNHKSDKSSAAASKDTLLYRLLPDAPASLADETSQAADFVNSMVYDQIGSRLLETLITNCPGKVFKALSHNFFGDRIATYVRNDIASYPALRVLNRFSKDDLVEAVKKIIPVVPLLVSKARYNVLKTLFERCDARGAYEEKSALTRALTDALGPNPKDLVPKLCHLVEDESADKDQFQQSPQNKTAVAAHGCHLVSTMLKTPGNASKVAQKSLVALPPDLLVKLATTAMASTTVLTTALASPAAPQNEFFHKALVGALAPHAAELAQSQFGHNVINAIVEIPSRGTDRCVPFHVKQTIIASLAGHERALRDSWMGRSVWRTWKGDMWKTRRSDWVKWAKEVDGPAEETKLKPWERRKLEQQKGPQPRQPPRETAKEDKE
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FPG_PARUW
Sequence: MPELPEVHTIVQDLKQSRLIGKKIISTEIFWPKTLAVPTPEIFCQQVQGQSIQNVDRRGKYIIFQLSNQMFLIVHLRMTGRFQFVTSQTPASPYVRIQFNFENGDQLRFHDTRKFGRWYLVSDVEEIIGHLGPEPLLSSFTFELFEDMMKNRKTLLKSLLLDQSFIVGLGNIYVDEALWEAKLHPLIPANQINLKHLKILYHSIKYVLEKGIQARGTTLGPGRTHYYRLDGSKGEHQTLLNVFRKTGHPCPRCGHLIEKLIVAQRSTHICPICQKK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: BDNF_CALRI
Sequence: SCMKAAPMKEVSIRGQGSLAYPGLRTQGNLGTLGGPNDATRGLTSLADTFEHVIEELLDEQQVIQPSKENKDADLYSSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSTSEWVTAAEKKTAVDMSGATVTVLEKVPVPKGQLKQYFYETKCSSKGYAKEGCRGIDKRYWNSQCRTTQSYVRALTMDNKKRVGWRFIRIDTSC
What is the function of this protein?
Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPD_DEIRA
Sequence: MQAQPIHARLMNGEVLSQDDATAFMREVMSGDMSGVRMAAALAALRVRGETPEEIAGFAQAMRESAVTVKVRPRDVLMDVVGTGGDGAHTFNISTTTAFVLAGAGVPIAKHGNRAASSRAGSADVLEALGVNLDASPEVIQEAIDTLGVGFMFARNYHPALRHAAPVRSDLAARTVFNILGPLSNPAGATHLVVGVFRADLTRTLAEALRHLGAKGATVVYGDGLDEFTVCGPNTVSGLRDGEIIDRTMHPEEFGVDLHPKTAIVGGSPAENAEITHALLTGGGTPAQKDIVALNAGAALRTAGRVGTIREGVEQAREVMKGGQGWEMLQKYGALTKR
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: BRE1B_ORYSI
Sequence: MDAAALQYENQKLVQQLEAQKSKMRALEGKFKELRDEQCSYDNTLICLNKMWNQLIDDLVLLGVRAGGDLNGLQALDHEEMSEESLESCPSEEIFLFRLLNSRNFRNNDDSSLSKLVEEALALRYSTTVTLMKSLQEAFAVQQARSESLSLALNGQNSSEDVIVALENHNDYLKEVVDNLRQAVSIINRKHEKYLDEIEAFKNNQSRELHEVKCLSGELEESMAELEESRRKLAVLQLQTGGGSLMNTSAPNGVNGSVSTDKSSDKGMGWRDLKDAVEEAKTLAANRLFELHETQEDNLILSKQLEDIQDQLKDENYIVTSKPYTILSDQLHHLNAEIERYRGLVEVLQNEKDQLMQKEEEMLAKAESVDAVQQSITTYKAKIEDLEHEIQKLMAEKNDLEIKAEEALQDSGKKDFKDEIHVMAASLSKEMELLDNQMNRSKDAASEALALREEADYLRTLLAKKIDEQKEISDRYNTQVTEIKSLKALIETLDQEKQELQFIVDMLGKECSESRAISEIEESENRARKQAEYLRKCLEEHNLELRVKAANEAETACQQRLSIAEAELEDLRAKVDASERDVMKLKESIRIKEAEVDGHISEIETIGQAYEDMQTQNQHLLQQVADRDDFNIKLVSDSVKMKQAYGSLLAEKNMLQKQLQHVNSSLESSKLKITSGEEQMKTYVAQAMKSSSENRHLAISLERTMLEVSDAEKELKWLRSATGSAEKEYEINQKKIAELKMELERERNERIKLEEEYEEVKNEVSELTSETEETTIQKLQDEIKECKAILKCGVCFDRPKEVVITKCFHLFCSPCIQRNLEIRHRKCPGCGTPFGQSDVREVKI
What is the function of this protein?
E3 ubiquitin-protein ligase that monoubiquitinates H2B to form H2BK143ub1.  H2BK143ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for H3K4me and maybe H3K79me.  It thereby plays a central role in histone code and gene regulation.  Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBC2/RAD6.
What are the official names of this protein?
E3 ubiquitin-protein ligase BRE1-like 2, RING-type E3 ubiquitin transferase BRE1-like 2.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADD_LACP3
Sequence: MDFQTLHQLSKTELHCHLDGSLSLSCIRQLAKMIDRKLPATDDELRRLVQAPADSENLGDYLKAFDFVAPLLQTKKALQLAAYDVVEQAAEENVRYIEIRFAPVFSLAGGLSLVEATQAVIEGLHQGMATYDIMAKALVCGMRQLPNTDNQTMFKTTAPLLGSTLVGGDFAGNEADFPTNVCAPAIKTAQSLGVPLTFHAGECHCPQNIGEAVRLGIPRIGHATACFDQPALIEKIVETGTTVELCLTSNLQTKAARTLAEFPYQALKKAGAKITINTDNRTVSNTTLTQEYQRYQQAFGTTAADFLAFNLNAIDAAFIPDADKKSLRDQLHQDYATYC
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: FRMD6_RAT
Sequence: MNKLTFHNNKVMQDRRRVCIFLPNDKSVSIIINVKILCHQLLVQVCDLLRLKDSHLFGLSVIQNNEHVYMELSQKLYKYCPKEWKKEASKGIDQFGPPMIIHFRVQYYVENGKLISDRIARYYYYWHLRKQVLHSQCVLREEAYFLLAAFALQADLGNFKRKVHHGDYFEPEAYFPAWVVSKRGKDYILKHIPNMHRDQFALTASEAYLKYIKEAVRLDDVAIHYYRLYKDKREVEGSLTLGLTMRGIQIFQNLEEEKQLLYDFPWTNVGKLVFVGKKFEILPDGLPSARKLVYYTGCPTRSRHLLQLLSNSHRLYMNLQPVLRHLR
What are the official names of this protein?
FERM domain-containing protein 6, FERM domain-containing protein 163SCII.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Can colocalize with actin.
Protein: TRPF_BRUC2
Sequence: MALDIKICGLKTPEAVAAALDGGATHIGFIFFPKSPRHITPDAAARLRAAATGRAVAVAVTVDADDEALDEIVKTVRPDMLQLHGGETPERVRFLKERYNLPVMKAFSIREAGDLEAIAPYRGIADRFLFDAKPPKGSELPGGNGISFDWNLLAALDADIDYMLSGGLNADNIAEALLKTGAPGIDISSGVECAPGEKDVRLIENFFQAVADANAQPFARRA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: YREP_BUCTC
Sequence: MKNIIEKMIYISRWLIFPIYLGLSFCLILLTLKFFQLVFFIFPEIFFISESGLILVILSLIDIVLVGGLLVMVMFSGYENFISKMNIEGDKLGWMGTMDVNSIKNKVSSAIVAISSVHLLRVFMETEKVSNEKIVWYVIIHLTFVVSAGGMAYIDRLNKSNINSSTRKCSVLVNRRKK
What are the official names of this protein?
UPF0114 protein in repA1-repA2 intergenic region.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YITK_BACSU
Sequence: MAKESSFDIVSKVELPEVQNAIQIALKEISTRYDFKGSKSDISLDKEELVLVSDDEFKLSQLKDVLVSKLIKRNVPTKNIDYGKVENASGGTVRQRAKLVQGIDKDNAKKINTIIKNSGLKVKSQVQDDQVRVTGKNKDDLQQIISAVRGADLPIDVQFINFR
What are the official names of this protein?
UPF0234 protein yitk.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: Y4FF_SINFN
Sequence: MFGEQPGLQVDNQSGLFIEGAYVSRSDEGDGGIDIILVGSDPTFAGNDDQTTGEFLRGVSRYAYFTVPGHTPIKNGPFRLANDRDGSLFADRTVIVAAMTLALQSVQYLRHPLADVTMGYDPSAPKNLVAKAQKRGFDAQLELDWKGYPSLTILGADPAARKSSPVAARENDEEIVFGFGR
What are the official names of this protein?
Uncharacterized protein y4fF.
Protein: CLYT_CLYGR
Sequence: MADTASKYAVKLRPNFDNPKWVNRHKFMFNFLDINGDGKITLDEIVSKASDDICAKLGATPEQTKRHQDAVEAFFKKIGMDYGKEVEFPAFVDGWKELANYDLKLWSQNKKSLIRDWGEAVFDIFDKDGSGSISLDEWKAYGRISGICSSDEDAEKTFKHCDLDNSGKLDVDEMTRQHLGFWYTLDPNADGLYGNFVP
What is the function of this protein?
Ca(2+)-dependent bioluminescence photoprotein.  Displays an emission peak at 470 nm (blue light).  Trace amounts of calcium ion trigger the intramolecular oxidation of the chromophore, coelenterazine into coelenteramide and CO(2) with the concomitant emission of light.
What are the official names of this protein?
Clytin, Phialidin.
What is the protein family that this protein belongs to?
Belongs to the aequorin family.