PharMolix/UniProtQA huggingface dataset:
Protein: PB1_CHICK
Sequence: MGSKRRRATSPSSSVSGGDFDDGHHSTNIPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNVLTADFQLLFNNAKAYYKPDSPEYKAACKLWELYLRTKNEFVQKGDAEEEDEDEEGHDSQELSSPGYLKEILEQLLEAVAVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGTYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANAIKKIFNMKKAEIEHSELAKSSLRLRTPSNLTASKLTGPSSQGKGSVGDERNSSNKYFRNKRSAQGDRLSAITMALQYGSESDEDAALAAAARYEGESEAESITSFMDTSNPLYQLYDTVRSCRNNQGQLISEPFFQLPSKKKYPDYYQQIKTPISLQQIRAKLKNHEYETLDQLEADLNLMFENAKRYNVPNSAIYKRVLKMQQVMQAKKKELARRDDIEDGDSMISSATSDTGSSKRKSKKNMRKQRMKILYNAVLEARESGTGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKMIEHNIRNDKYVGEEAMIDDMKLMFRNARHYNEEGSQVYNDAHMLEKILKEKRKELGPLPEDDDVASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYITIKKPVDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRREIEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQENMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKEKKEKLPKEIEEDKLKREEEKREAEKSEDSSGSAGLSSLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVYVCESRYSAKTKSFKKIKLWTMPVSSVRFVPRDVPLPVVRVASVFANTDKAEEEKHSDTLDDSKVGESILHLEKDKEDVPVEMSNGEPGCHYFEQLCYNDMWLKVGDCVFIKSHGLVRPRVGRIEKMWVRDGAAYFFGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMSCILGKCAVLSFKDFLCCRPTEISENDVFLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQQLEAKFAELGGGDEDMEEMGEEEGDITETPSMPQLQTPLTSELDIMPYTPPQSTPKSVKGSTKKEGSKRKINMSGYILFSSEMRPVIKAQHPDYSFGELSRLVGTEWRNLEATKKAEYEGMISGYPPVLPPLQGPVDGIVSMGSMQPLHPGVPPPHQLPPGMPGIPGIPPPGVIGQNVSPMVGTPAPGAGPFGQQIGILGPPGQQAPPPYPGQSPATQPVMQQPSTPMFVSPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNIENV
What is the function of this protein?
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).
What are the official names of this protein?
Protein polybromo-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPR37_CAEBR
Sequence: MSMKFLTGLQDLLGLYETGTAASSPASPIPPTSPSMFATPPHQQSHSSATSVRKKVCQEANSSADDPDSDARIRQCSHTRTVSFPADIGLITGYHDAPSALFHSIENSNRSIDPTEILKYYREACQRRQCAPSVGVEKQIGYFHKSPDTRQELLSLKGERVSHAQMEALEEIFKRVQFNTIDFEYTFLDDDCAISLGEMIEFYDSCVRLNLSFNKQIDVRGWAAMFKSIRNAISLQMLNLRYTNLNDRSIPSLCKLARAQPSASLTCIHLENTQMSGKNLLVLICALKYNTGIRELYLGDNGLQPTDGSHIYQLISSNTCLQLLDLRNNNIGDSGVRHICEGLRNRESIEKSALSAMVLWNNNVTGASMDSLAEALMENTKIETLNIGSNNLGVEGVARLKPALVSNSHLHRLGLQNTGINCEGAIILAECIADNTALLRVDIRDNPIALAGLLALHSAMKMNTSITLLNIDATCVRMSSEKVREYQDEFERYFREIQTYCDRNKDDVLKKLTVTFEDQDHVSEDTEKENKDADNDDKEPENEDGDTTPETSDSDASADQSDSPADKEKSEKSKKENNNNEKRPLMASASTSKVCQKERHQRFVRSSSLTCAETVHDIHDRLREMSGSTHSLDAAMSAATTLSPTMLTATYGSTPGPLDASSNTDSMKTIKKTFTVTSAAPPTLALAEWGSLPALPQASPTSTPVVRKLRRFSVSPSSSVFDVATTSSASTSPIPEVTASPHPIRPSTLAIGIPVTGSVPAGPSSAPMIFVDHHTEAASPDCTNTCEEPTTSREAERKRAEETIRQRRGQKEIKDTCRAVINDLLNYVEYEEKSQVERKASLLLRNAFSRPNPEELLKNLQRAESPLTPRTPVTPSRVLEIAEELEEETDEQVCQSVVRCLVRDVLQTEKNELRSTLDRRRRHNSVRNSPV
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 37 homolog.
What is the protein family that this protein belongs to?
Belongs to the PPP1R37 family.
Protein: TPIS_ECOK1
Sequence: MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_CHLPM
Sequence: MLAKRIIPCLDVRDGRVVKGINFEGLRDAGSILEQARFYNNELADELVFLDISASLESRKTTLEEVLKVSGEVFIPLTVGGGINSVERAKEVFLHGADKVSVNTAAVNNPELISRIAEKYGSQAVVVAVDIKKIGDRYIVHTHSGKQPTEYEALEWALKVQELGAGEILLTSMDRDGTKEGYDNESLALISTSVHIPVIASGGAGSLEHLYDGFTKGRADAALAASIFHFRQHSIREAKQYLHDRGITVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_STRMK
Sequence: MTRILGIDPGSQRTGVGIIDVDATGRVSYVHHQPLVLLGADDFPQRMKLLVLGLADLCREYEPQEVAIERVFMARNPDSALKLGQARGAAISAVVLRDLPVHEYAASEIKLAVVGRGGAEKQQVQHMVGLMLNLKIKLQADAADALAVAITHAHVRATANRLGLSARQAWGRK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CREC_NEOFI
Sequence: MVAISLSFVLPPPPPRYTVPVAYAAGAANGMAVPVVETNNILSHPEGGCPLQVGEGTYELKDDLHLATPPPHPSEAPIINPNPLATVPTPPTSGVKVSLVCVSPRSKTPSFISKQIVTAPPFGDGNPALVPAPVKDGLKRRKPKNNIIKSSSSFVSRVITHEAATKRLSERSPEGLFAFANINRAFQWLDLSSKQKEEPLAKILFTKAHMLCHDINEVTKSPSHIDMVMGSSAGDIIWYEPISQKYARINKNGVVSNSPVTHIKWIPGSENLFMASHANGQLVVYDKEKEDALFTPEIQDQSAEALKASSRQPLQVLKSVNSRNQKTNPVALWKLANQRISHFAFSPDQRHLAVVLEDGSLRVMDYLKEEVLDIFRSYYGGLICVCWSPDGKYIVTGGQDDLLTIWSFPERKIVARCQGHNSWVSAVAFDPWQCDERTYRFGSVGDDCRLLLWDFSVGMLHRPKVHQASARQRTSMVAGSSQYGNRHRADSAGNRMRSDSQRTANTYESCDQAVRHPVEPRARTALLPPIMSKVVGTDPICWLGFQEDCIMTSSLEGHIRTWDRPREGINDKYNDQSSSPAVSASAAGSGSVSGLAESTMGSL
What is the function of this protein?
Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression.  CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways (By similarity).
What are the official names of this protein?
Probable catabolite repression protein creC.
What is the protein family that this protein belongs to?
Belongs to the WD repeat creC family.
Protein: UGPA_ECOL6
Sequence: MSSSRPMFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGFSSQFVGLDNFVTLFHDSYYLDAFWTTIKFSTFVTVSGLLVSLFFAALVEYIVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFLVIVLTVVQFRYVESKVRYQ
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
sn-glycerol-3-phosphate transport system permease protein UgpA.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NBLIK_STRGG
Sequence: MIEIPSDLHPDLVPLAFLLGNWAGAGVSDFPGAEKCNFGQEVTFSHDGRDFLEYVSHTWVLDDEGKQVRPLETETGYWRIDKDRKVEVVMARDQGVIEIWYGELADQKPQIDLVTDAVARTAASGPYSGGKRLYGYVKSDLMWVGEKATPEVELRPYMSAHLKKVVTPEEVAEMARNLPDMPDDGIAFFK
What are the official names of this protein?
Ferric nitrobindin-like protein.
What is the protein family that this protein belongs to?
Belongs to the nitrobindin family.
Protein: RRF1_KLULA
Sequence: MSLQAFRIGLLSTTAAPLAYARPFSSYAALLAKKKGKTSGKPGKADNEEPIEIIDVKKYVIDATKQFEKTLELHKRKLAEQKVGTASPTIFNDLRVGKEGQKFTELAATSLKGRNALIVTVFDPKDTKNIVSAIMAAGLNLNPERIPNNDQQLKVSLPPITTETRQAVCKDLKKVFEDYKHSALKESLGHVRGEIMKELKHLQKKNDDVKKVIQDVEKIHKEYTIKLQEQLKQAEKSVMNQ
What is the function of this protein?
Necessary for protein synthesis in mitochondria.  Functions as a ribosome recycling factor in mitochondria (By similarity).
What are the official names of this protein?
Ribosome-recycling factor, mitochondrial, RRF, Ribosome-releasing factor, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HEM1_METST
Sequence: MLVNIRIDFKIADIETMEKSYAKLDMINAELHEKLDILEEVTLKTCNRYEIYLLIDEEVNIPTTTFIVEKNDMAINHLLRLASGLESMIMGEDQILGQIKTARKNAIKNKTIGPKLEKVFTKAIHVGQTIRKNTHINEGGVSVGSGAVELIEEKYGSLKGKNVLIIGAGEMGTVVSKALLEKETNTIVVANRTYDKARQLAQELDGEAIKFDEMNNELVNIDIVISSTGAPHSIISKERIAFLPEEHLHDMIMLDLANPHDIENDVQELGVKLYNLDDLRYVTDKNKERRNKEAIKAEAIIEDETLLLKESLKQMEITPILSSLNIEAEKIRKQELDKTLHMLDLDKKSSKKVDYLTRSITDKLLYNIINNLKEAAANNDKDTIRNAKKILLEYN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NUOD2_ANASK
Sequence: MSEAKGVGGIDPRATPGSAGAGERPPMGTLSPRAGEGELYAPMPSKHMVINLGPSHPAMHGVTRAVVELNGEIIEGMKLDIGFLHRGFEKSCENVTWGQVFPYTDRLNYVSSIMNNVGFALAVEKLAKLEIPERARYLRVITSEIHRICDHLTLVGAMAMELGAMTVFLYGIEARDLLWDRLAELCGARLTSNYARIGGVARDIPEGWQEKTLKVLDRVVAIREEIGQLLNRNRIFIDRCLNTGKVSREDALELGFTGPCLRASGEPYDVRKAAPYLVYDRLDFDIPVGSNGDNFDRYLMRMEEMRQSDKIIRQCFEQMAPGEIIVQDFRYALPPKPLVYGTIEGVMAHFKLVMEGIKVPAGEVYSYTEAANGELGFYVVSDGGGRPYKLGLRAPGWPMLAALPVMTKGSLLSDLIPTFDSINMIGGEVEQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PYRG_ONYPE
Sequence: MNNKDLKTKFIFITGGVVSSLGKGITAASIGQILKNRGLKVSIQKLDPYINIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFLDENMSKKSNVTAGQIYQSVINKEREGKYLGKTVQVIPHITEEIKQKLIDVALFHKSDVVIVEIGGTVGDIESSPFLEAIRQVRFDFGYHNVLYLHTTLVPYLKKAQEIKTKPTQHSVKELRALGIQPQILVLRSEVPINPETKNKIAALCDINPQAIFEALDVDILYQMILNLHHQGIDDFILQHFKLTNFSNADLQSWKQLITRIQNLEKKVVIALVGKYIVLHDAYLSIIEALKHASYQYNCKLEIKWIDAEKVTPDNISSLLEDYDGILVPYGFGNRAIEGKILAINYARTNNIPFFGICLGMQLAVIEYARNVLHLQGANSLEVDEKTPHPVITKKIVDSNLGGTLRLGSYPCHLKANTKSKAIYNQEIIYERHRHRFEMNPHYVALFEKNNDFVVSGINQEQKLCEIVELKSHPWFIAVQFHPEFLSRPLKPHPLFKGFVEASLLNQKNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: G6PI_HAEIN
Sequence: MKNINPTHTHAWKSLEAHKAELSNITIQDLFKQEKNRFDDYSLTFNNQILIDFSKNNINQTTLSHLRQLAQECALDSAKEAMFTGEKINRTENRAVLHTALRNRTNTPVLVDGKDVMPEVNAVLAKMKDFCQRIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAETLKKVNPETTLFLVASKTFTTQETMTNAQSARDWLLKAAKDESAVAKHFAALSTNAKDVEKFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSIGFENFEALLNGAHEMDKHFLSTPIEQNIPTTLALVGLWNTNFLGAQTEAILPYDQYLHRFAAYFQQGNMESNGKYVDRDGNVIKNYQTGPIIWGEPGTNGQHAFYQLIHQGTTLIPCDFIAPAQRHNPLADHHNKLLSNFFAQTEALAFGKTKEEVEAEFVKAGKSLDDVKNIVPFKVFTGNKPTNSILVQKITPFTLGALIAMYEHKIFVQGVIFNIFSFDQWGVELGKQLANRILPELTDSEKVASHDSSTNGLINQFKAWR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_ASPCL
Sequence: MTLEAIRYSTGKLVIIDQLQLPYVEKYIEVPTSKDAWHAIKKMRVRGAPAIAIVAALALASELHTLMAHDKLSNRAEEVRLFIQEKLDYLVSSRPTAVNLSDAARKLAAHVSDHAEMPNSTGRAVAEAFIQAAEEMLAKDLKDNTNIGKYGAEWIIRNALAGGRSKATILTHCNTGSLATSGYGTALGVIRALASKNALAYAYCTETRPYNQGSRLTAYELVHENLPATLVTDSMVAALLAKAEAAVDAIVVGADRVAANGDTANKIGTYALAVLAKFHGVKFLVAAPLTTIDRSTKSGADIVIEERPASEVTTIKGAVETESSCDRIKLETVRIAAEGIHVWNPAFDVTPSALIDAIITERGVVERGTDGRYNFDGIFEDHSAF
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CHS3_YEAST
Sequence: MTGLNGDDPDDYYLNLNQDEESLLRSRHSVGSGAPHRQGSLVRPERSRLNNPDNPHFYYAQKTQEQMNHLDVLPSSTGVNPNATRRSGSLRSKGSVRSKFSGRETDSYLLQDMNTTDKKASVKISDEGVAEDEFDKDGDVDNFEESSTQPINKSIKPLRKETNDTLSFWQMYCYFITFWAPAPILAFCGMPKKERQMAWREKVALISVILYIGAIVAFLTFGFTKTVCSSSKLRLKNNEVSTEFVVINGKAYELDTSSRSGIQDVEVDSDTLYGPWSDAGKDASFLFQNVNGNCHNLITPKSNSSIPHDDDNNLAWYFPCKLKNQDGSSKPNFTVENYAGWNCHTSKEDRDAFYGLKSKADVYFTWDGIKNSSRNLIVYNGDVLDLDLLDWLEKDDVDYPVVFDDLKTSNLQGYDLSLVLSNGHERKIARCLSEIIKVGEVDSKTVGCIASDVVLYVSLVFILSVVIIKFIIACYFRWTVARKQGAYIVDNKTMDKHTNDIEDWSNNIQTKAPLKEVDPHLRPKKYSKKSLGHKRASTFDLLKKHSSKMFQFNESVIDLDTSMSSSLQSSGSYRGMTTMTTQNAWKLSNENKAVHSRNPSTLLPTSSMFWNKATSSPVPGSSLIQSLDSTIIHPDIVQQPPLDFMPYGFPLIHTICFVTCYSEDEEGLRTTLDSLSTTDYPNSHKLLMVVCDGLIKGSGNDKTTPEIALGMMDDFVTPPDEVKPYSYVAVASGSKRHNMAKIYAGFYKYDDSTIPPENQQRVPIITIVKCGTPAEQGAAKPGNRGKRDSQIILMSFLEKITFDERMTQLEFQLLKNIWQITGLMADFYETVLMVDADTKVFPDALTHMVAEMVKDPLIMGLCGETKIANKAQSWVTAIQVFEYYISHHQAKAFESVFGSVTCLPGCFSMYRIKSPKGSDGYWVPVLANPDIVERYSDNVTNTLHKKNLLLLGEDRFLSSLMLKTFPKRKQVFVPKAACKTIAPDKFKVLLSQRRRWINSTVHNLFELVLIRDLCGTFCFSMQFVIGIELIGTMVLPLAICFTIYVIIFAIVSKPTPVITLVLLAIILGLPGLIVVITATRWSYLWWMCVYICALPIWNFVLPSYAYWKFDDFSWGDTRTIAGGNKKAQDENEGEFDHSKIKMRTWREFEREDILNRKEESDSFVA
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer (Probable) (PubMed:9760183).  Appears to be responsible for synthesis of the majority of the chitin found in the cell wall periphery (PubMed:2050738).  It is involved in the synthesis of the chitin ring that forms in the cell wall just before bud emergence (PubMed:2050738).  This ring remains at the base of the bud as the bud grows and ultimately forms part of the bud scar marking the division site on the mother cell (PubMed:2050738).  Also catalyzes the synthesis of chitin laid down during mating and spore cell-wall synthesis (PubMed:2050737, PubMed:2050738, PubMed:1293886).
What are the official names of this protein?
Chitin synthase 3, Chitin-UDP acetyl-glucosaminyl transferase 3, Class-IV chitin synthase 3.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class IV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bud neck. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localizes to a ring on the surface of cells about to undergo bud emergence and in the mother-bud neck of small-budded cells (PubMed:8909536). Delocalized throughout the plasma membrane during heat shock (PubMed:12928491). Also localizes to intracellular membrane-bound particles called chitosomes, proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum (PubMed:8970154, PubMed:12928491).
Protein: CHVI_RHIME
Sequence: MQTIALVDDDRNILTSVSIALEAEGYKVETYTDGASALEGLLARPPQLAIFDIKMPRMDGMELLRRLRQKSDLPVIFLTSKDEEIDELFGLKMGADDFITKPFSQRLLVERVKAILRRAANREAAAGGTGPAKNADTPSRSLERGQLVMDQERHTCTWKNESVTLTVTEFLILHALAQRPGVVKSRDALMDAAYDEQVYVDDRTIDSHIKRLRKKFKMVDNDFDMIETLYGVGYRFRETA
What is the function of this protein?
Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan.
What are the official names of this protein?
Transcriptional regulatory protein ChvI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCA_ECODH
Sequence: MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXS_YERPB
Sequence: MSLDIAKYPTLALAENPEELRMLPKESLPKLCDELRQYLLTCVSRSSGHFASGLGVVELTVALHYVYNTPFDHLIWDVGHQAYPHKILTGRRDRISTIRQKDGLHPFPWRGESEYDVLSVGHSSTSISAGLGMAVAAEREGKGRRTVCVIGDGAITAGMAFEAMSHAGDIHSDMLVILNDNEMSISENVGGLNNHLAQLLSGKLYASLREGGKKAFSALPPIKDLLKRTEEHLKGMVVPSTLFEELGFNYIGPVDGHDVHTLTQTLKNMRDLKGPQLLHIMTKKGKGYAPAEKDPIGWHAVPKFDPASGTLPKSQSSLPTYSKIFGEWLCETAAKDSKLMAVTPAMREGSGMVRFSREYPQQYFDVAIAEQHAVTFAAGLAIGGYKPVVAIYSTFLQRAYDQLIHDVAIQNLPVLFAIDRGGLVGADGQTHQGAFDLSFMRCIPNMVIMAPSDENECRQMLYTGYHHNGPAAVRYPRGNGTGAVLEPLEMLPIGKGVLRREGEKIAILCFGTLLAQAQLAAENLNATLVDMRFVKPLDEELVLEMAAKHQVLVTVEENAIMGGAGSGVNELLMAKRRWVPVLNIGLPDLFVPQGEQDEMRSELGLDAAGIQRQIEAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: THIG_PSEE4
Sequence: MSNVRSDKPFVLAGRTFQSRLLVGTGKYRDMEETRLATEASGAEIVTVAVRRTNLGQNAGEPNLLDVLSPEKYTILPNTAGCFDAVEAVRTCRLARELLDGYKSHENRTLVKLEVLADQKTLFPNVIETLKAAEVLVKDGFDVMVYTSDDPIIARQLAEAGCIAVMPLAGLIGTGLGICNPYNLQIILEESKVPVLVDAGVGTASDATIAMEMGCEAVLMNSAIAHAQQPVLMAEAMKHAILAGRMAYLAGRMPKKLYASASSPLEGLIK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_CORA7
Sequence: MLILGIESSCDETGVGIIELSDNGHMEIRADVVASSMEQHARFGGVVPEIASRAHLEAMPQVMKAALEEAGVEKPDAVAATVGPGLAGALLVGASAAKAFASAWGVPFYGVNHLGGHVAVANLEGEELPHSVALLVSGGHTQLLEVEAVGKPMKELGTTLDDAAGEAYDKVSRLLGLGYPGGPVIDKLAAQGKPTIDLPRGLSKAEDLRGPNRHNFSFSGLKTAVARHVEKAEREGTTVQVEDLCASFQEAVADVLTAKAVRACQDTGAKVLLLGGGVAANSRLRALAAKRCESAGIELRVPRFKLCTDNGVMIAAVAAQLIHEGAEPSGLACGTDTQLEVEVPLVAAR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCE_RGDV
Sequence: MQAKTTSEEYVIPNFAQTINNRTIVNIFESCKYRSPLIICALNDAVLAKEYSNSMAMGSGTITFMIDNDVDIMSSLYTTFRTVSTLLLMGNQLCVFIVVPMSVISTDALTAIAYAYRGAMIELRHYGRGDDYVQERLESLFKLSPLCGTPHMGPKYYGPTVFSELLDLSHHNKTSWYSVIDYSMFTRTALVGFASYMMKTLSLNSSIVNIVGYNPPYVWAAMMHGVTIRYIEKEIPNPKGKGPMGLIMPELNGRVLTNKVKYVLHNPQIKLLCLDSMMFMSSRNIVYIGAYPATHLLDMNLRGWNIYAVDPEITQQWISDMKAKTGANICASSRKFMFDVSENIKINEFFGNQPYSIIDDSWVPDNYEQFQDKKRNYFQELVKSDQKVTLITMKWNTRKNVTCEKLLALLPQPYGGKLYEMRAFFHRNGIGSITIDANSVEKYIQKFQELPLGAQVGTQKFMHTMISRVQDVMSIQPKKGDVIIASYSLSNASNPKKKVLEYLTKASKSEAMIIFGAPNLERVKYMRERGVLPGNNITINGEKITFNNPSGKKWTDFGYTNSELLACDMIEVTIEQMVSFMSTSFRGTGYYSNSIYNDLFSWFIPIWVWNQTMQIQDIRLSPVALVKCFTTKIRNLCYVPHSTYYALRGHLVAKMFSENNIENNCYSISGKSNETFTVLKDFKFPTSIGVLEFKAGEKVNISGHLLSLAVAAHFVAVPVTMWARHIKYMTVDRQKPPDVDRILFFDNKIKRNTLEKWHTKSEVILAALIAGEYVGLMLNNFHSKAIVDDLCNTVLATFR
What is the function of this protein?
Enzyme involved in mRNA capping (Potential).  Binds to GTP and might have guanylyltransferase activity.  Together with the RNA-directed RNA polymerase P1 and protein P7, forms an transcriptional complex positioned near the channels situated at each of the five-fold vertices of the core (By similarity).
What are the official names of this protein?
Putative mRNA-capping enzyme P5, Structural protein 5, mRNA guanylyltransferase P5.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus protein P5 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Located inside the inner capsid. Found in the interior of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: Y152_RHOPA
Sequence: MDATDDIRAGELASDWSGSPDAGVVFIGRIHTPWNRLKECPRHGRADGPVCRIEVFETWLPALAGIDDGTLLEVFYWLHRSRRDLLLQCPRNDGDARGTFSIRSPLRPNPIGTSIARVDRRDGANLFIRGLDCLDGTPLVDLKPDRAEFMPLAPPKPGDFQVGEPRR
What are the official names of this protein?
S-adenosyl-L-methionine-binding protein RPA0152.
What is the protein family that this protein belongs to?
Belongs to the tRNA methyltransferase O family.