PharMolix/UniProtQA huggingface dataset:
Protein: GATA_CHLTA
Sequence: MYRKSALELRDAVVNRELSVTAITEYFYHRIESHDEQIGAFLSLCKERALLRASRIDDKLAKGDPIGLLAGIPIGVKDNIHITGVKTTCASKMLENFVAPFDSTVVRRIEMEDGILLGKLNMDEFAMGSTTRYSAFHPTNNPWDLERVPGGSSGGSAAAVSARFCPIALGSDTGGSIRQPAAFCGVVGFKPSYGAVSRYGLVAFGSSLDQIGPLTTVVEDVALAMDAFAGRDPKDSTTRDFFKGTFSQALSLEVPKLIGVPRGFLDGLQEDCKENFFEALAVMEREGSRIIDVDLSVLKHAVPVYYIVASAEAATNLARFDGVRYGHRCAQADNMHEMYARSRKEGFGKEVTRRILLGNYVLSAERQNIFYKKGMAVRARLIDAFQAAFERCDVIAMPVCATPAIRDQDVLDPVSLYLQDVYTVAVNLAYLPAISVPSGLSKEGLPLGVQFIGERGSDQQICQVGYSFQEHSQIKQLYPKAVNGLFDGGIE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: DRE1D_ARATH
Sequence: MNPFYSTFPDSFLSISDHRSPVSDSSECSPKLASSCPKKRAGRKKFRETRHPIYRGVRQRNSGKWVCEVREPNKKSRIWLGTFPTVEMAARAHDVAALALRGRSACLNFADSAWRLRIPETTCPKEIQKAASEAAMAFQNETTTEGSKTAAEAEEAAGEGVREGERRAEEQNGGVFYMDDEALLGMPNFFENMAEGMLLPPPEVGWNHNDFDGVGDVSLWSFDE
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates abscisic acid- and dehydration-inducible transcription.  CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation.
What are the official names of this protein?
Dehydration-responsive element-binding protein 1D, Protein DREB1D, C-repeat/dehydration-responsive element-binding factor 4, C-repeat-binding factor 4, CRT/DRE-binding factor 4.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRA2A_HUMAN
Sequence: MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRSYSPRRY
What is the function of this protein?
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.
What are the official names of this protein?
Transformer-2 protein homolog alpha, TRA-2 alpha, TRA2-alpha, Transformer-2 protein homolog A.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATG5_ORYSI
Sequence: MAAQRDDEAGWSAEAARRVWGGAVPLQVHLHDADVTTLPPPPPFLTLGPRIGYLPLLVPIIKAHFSSTLPPGIDTVWFEYKGLPLKWYIPIGVLYDLLCADPERPWNLTVHFRGYPSEILTPCDGEDSVKWSYMNSLKEAAFIITGNSKNVMNMSQADQGALWQSVMKGNLDGYMNISTRLKLGPFEEDCLVRTSSVEGQQGSDEPESPGSGKPCRVPVRLYVRSVQEDLYDLEDALPVGDWESISYINRPFEVRREEGRSYITLEHALKTLLPEFFSSKASRIPDDSETAPQAPDSAPNDDSDVTPRSCEKLESSASSSPQEANVANKGKIVKLVRVQGIEVDMDIPFLWVANNLKNPECYLHICVYVGTRKREPKDGR
What is the function of this protein?
Required for autophagy.  Conjugation to ATG12 is essential for plant nutrient recycling (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_THEFY
Sequence: MVGVGTDVHPFQTGRPLFLAGLEWPDEVGLSGHSDGDVAAHAACDALFSACALGDLGSQFGTSDPRWRGASGVALLTEAAQRVRAAGYEIGNIAIQIIGNRPKFAPRRHEAEKVLSAAVGAPVSCAATTTDGLGFTGRGEGIAAVATALCVRVR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: MUTS_AQUPY
Sequence: MGKEEKELTPMLAQYHQFKSMYPDCLLLFRLGDFYELFYEDAVVGSKELGLVLTSRPAGKGRERIPMCGVPYHSANNYIAKLVNKGYKVAICEQVEDPSKAKGIVKRDVIRVITPGTFFERETGGLCSLYRKGKSYLVSYLNLSVGEFIGAKVKEEELIDFLSKFNIREVLVKKGEKLPEKLEKVLKLHITELEEEFFEEGKEELLKDYGVPSIKAFGFQDEDLSLSLGAVYRYAKATQKSFTPLIPKPKPYVDEGYVKLDLKAVKGLEITESIEGRKDLSLFKVVDRTLTGMGRRRLRFRLLNPFRSIERIRKVQEAVEELINKREVLNEIRKTLEGMSDLERLVSRISSNMASPRELIHLKNSLRKAEELRKILSLLDSEIFKEIEGSLLNLNKVADLIDKTLVDDPPLHVKEGGLIKPGVNAYLDELRFIRENAEKLLKEYEKKLKKETGIQSLKIGYNKVMGYYIEVTKANVKYVPEHFRRRQTLSNAERYTTEELQRLEEKILSAQTRINELEYELYRELREEVVKELDKVGNNATLIGEVDYIQSLAWLALEKGWVKPEVHEGYELIIEEGKHPVIEEFTKNYVPNDTKLTEEEFIHVITGPNMAGKSSYIRQVGVLTLLAHTGSFLPVKSARIPLVDAIFTRIGSGDVLALGVSTFMNEMLDVSNILNNATKRSLIILDEVGRGTSTYDGIAISKAIVKYISEKIGAKTLLATHYLELTELERKVKGVKNYHMEVEETDEGIRFLYILKEGRAKGSFGIDVAKLAGLPEEVVREAKKILKELEGEKGKQEVLPFLEETYKKSVDEEKLNFYEEIIKEIEEIDIGNTTPVKALLILAELKERIKSFIKR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: OXR1_KLULA
Sequence: MSGFRNRIQSWGKGLGTVLSDSIGDESSEKTSRSIQHNHYEEDDALPPVHLIGYSEKTKNRLLSKEMCEELRQLMPTRIQLYTEWTLLYSLEQHGASLHSLYDKLKYDTNNNARVGYVIVIRDRKGGIFGGYANETFHPTDSRRYYGNGECFLWKMEKVPDLQLHDKHDCKQDSHNWQLRGFPYTGENEFSIYCTSTFLSMGAGDGHYGLWIDDGLFRGVTFPSMTFGNDILSREGSKFHIVGVEVWRVG
What is the function of this protein?
May be involved in protection from oxidative damage.
What are the official names of this protein?
Oxidation resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the OXR1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARGC_AERS4
Sequence: MLNTVIVGASGYAGAELAALVQNHPQLKLFGLYVSAGSQDAHKRFSSLHPQWVGALDQPLLPLDEDGMTRILTQADLVLLATAHEVSAELAPKFLAKGLPVFDLSGAFRVKDQQFYSSFYGFTHENEQLLEQAAYGLAEWNSDAIAAAQLIAVPGCYPTASLCALKPLQQAGLIAEGWQPIINAVSGVSGAGRKAAINTSFCEVSLSPYGTFNHRHQPEISHHLGKEVLFQPHLGNYVRGILATIYVQMADGVTPTQVDQAFLKAYEGKPLVRLTGQMPSIRGVASTPYCDIAWQQQGNMLVVVSAIDNLLKGAASQAMQCINIKFGFDPATGLI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NBP35_SCHPO
Sequence: MQIQETVPLDAPEHCPGPSSENAGTASACEGCPNQQICASAPRGEDPDLPLVVERLKEIKHKILVLSGKGGVGKSTFSSQLAWGLSLEEDKQIGLMDVDICGPSIPRIMGVEKEEAHQSSKGWSPIYVCPNLAVMSIGFLLPSEDSSVIWRGPKKNGLIKQFIKDVNWENLDYLIVDTPPGTSDEHLSLVQFFKNSGIDGAVVVTTPQEVALQDVRKEIDFCRKASIPILGLVENMSGFVCPSCKGKSNIFTITTGGGEALAKEMGLPFLGKIPLDPLIARSCDFGKSFIDECPESPASEIIIDIINKIDESLQKRQ
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor nbp35, Nucleotide-binding protein 35.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_SHESW
Sequence: MEALRQRIEAAFEARADITPSTVDANVRSDVQHVINMLDKGEVRVAEKIDGQWHVHQWLKKAVLLSFRIFDNAVIDGAETKYFDKVPLKFAEYDEARFKAEAIRVVPSATVRKGSFIGKNTVLMPSYVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEIVEGVVVEEGSVISMGVYIGQSTRIYDRETGEVHYGRVPAGSVVVSGNLPSACGKYSLYAAIIVKKVDAKTRGKVGINELLRIVD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_GRAFK
Sequence: MAKESMKAREVKRQKLVKKYAEKRAALKEAGDYEGLQKLPKNSSPVRLHNRCKLTGRPKGYMRQFGLSRVMFREMANQGLIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: SYT_PSEMY
Sequence: MPTITLPDGSQRSFDHPVSVLEVAQSIGAGLAKATLAGKVNGKQVDACDVIDTDATLQIITPKDEEGLEIIRHSCAHLVGHAVKQLYPNAKMVIGPVIDEGFYYDIAIDRPFTPDDMAAIEKRMAELIDKDYDVIKKMTPRAEVIELFRSRGEEYKLRLIDDMPDEKAMGLYFHEEYVDMCRGPHVPNTRFLKAFKLTRISGAYWRGDSKNEQLQRIYGTAWADKKQLAAYIQRIEEAEKRDHRRIGKQLDLFHLQEEAPGMVFWHPNGWTVYQVLEQYMRQVQRENGYVEVRTPQVVDRILWERSGHWSNYAENMFTTASENRDYAVKPMNCPCHVQIFNQGLKSYRDLPLRLAEFGACHRNEPSGALHGIMRVRGFVQDDAHIFCTEDQVKKEAADFIKLTLQVYADFGFTDIAMKLSTRPAKRVGSEELWDRAEGALADALNESGLAWEYQPGEGAFYGPKIEFTLRDCLGRNWQCGTLQYDPNLPERLDASYIAEDNNRKRPVMLHRAILGSFERFIGMLIEHYAGSFPAWLAPTQAVIMNITDKQADFAREAEKTLNQSGFRAKVDLRNEKIGFKIREHTLLKVPYLLVIGDREVETRSVAVRTREGVDLGSMPLEQFAAQLQQAVSRRGRQDLE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCLC_PSEKB
Sequence: AGMGTSIHLAAALLAAQAGVDLLHVPYKGSTPAAADLIAGRLSMMVDSITAQQSFIKSGRVRALGVTSLQPAPSLPGIPPLAQAADQPNFEVLTWFGLFVPSRTSPDIVKVLNTAMNEALKTPEVQKALADIGASAQGGTSQALGVLWDNEIDRWGQLIVHHRLNTNEL
What are the official names of this protein?
UPF0065 protein in clcB-clcD intergenic region.
What is the protein family that this protein belongs to?
Belongs to the UPF0065 (bug) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PDXT_PYRFU
Sequence: MVKIGVIGLQGDVSEHIEATKRALERLGIEGSVIWVKRPEQLNQIDGVIIPGGESTTISRLMQRTGLFDPLKKMIEDGLPAMGTCAGLIMLAKEVIGATPEQKFLEVLDVKVNRNAYGRQVDSFEAPVKLAFDDKPFIGVFIRAPRIVELLSDKVKPLAWLEDRVVGVEQGNVIGLEFHPELTDDTRIHEYFLKKIV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SYP_SOLUE
Sequence: MAESPITARSQDFAAWYQDVVLQGDMAEPAEIVKGCMVIKANGYAVWEVLQRELDDRFKATNHQNVYFPLLIPQSFLKKEAEHVEGFAPELAVVTVAGGKELEEPYVIRPTSETIIGHFFSKWIHSYRDLPLLYNQWANVIRWELRTRMFLRTTEFLWQEGHTAHSNHEEAVEEVLRILDLYAQVAEDIMAMPVIKGVKTHAEKFAGALKSYSIEAMMQNGLALQAGTSHDLGQNFGKAFDVQFQSKEGQLEYVWQTSWGVSTRLIGGLIMTHSDDKGLVLPPKLAPVKSVIVPIYRKEEERAAVLEAAHRIAKEIGAKVDDREGQSPGAKFFHWERRGVPVVLELGPRDLASGKIVLKRRDTGTKEPIDQSEVGAKVAAALEDMQKGLYTRAKDRMKANTVLANSIEEVEAILKDATAEKGGGKFVMAHIKDEPACDARLKEFKATVRNIPLVDEYDGPGKCIVSGETIEKRAVIAKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_ECO57
Sequence: MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRVYTGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRIRLSIKEATEQSQPAAAPEAPAAEQGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCM2_ARATH
Sequence: MAGENSDNEPSSPASPSSAGFNTDQLPISTSQNSENFSDEEEAAVDTQVIRDEPDEAEDEEEEEGEDLFNDTFMNDYRKMDENDQYESNGIDDSVDDERDLGQAMLDRRAADADLDARENRLANRKLPHLLHDNDSDDWNYRPSKRSRTTVPPRGNGGDPDGNPPSSPGVSQPDISMTDQTDDYQDEDDNDDEAEFEMYRIQGTLREWVMRDEVRRFIAKKFKDFLLTYVKPKNENGDIEYVRLINEMVSANKCSLEIDYKEFIHVHPNIAIWLADAPQPVLEVMEEVSEKVIFDLHPNYKNIHTKIYVRVTNLPVNDQIRNIRQIHLNTMIRIGGVVTRRSGVFPQLQQVKYDCNKCGAVLGPFFQNSYSEVKVGSCSECQSKGPFTVNVEQTIYRNYQKLTIQESPGTVPAGRLPRHKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTKNGFPVFATVVEANYVTKKQDLFSAYKLTQEDKTQIEELSKDPRIVERIIKSIAPSIYGHEDIKTALALAMFGGQEKNIKGKHRLRGDINVLLLGDPGTAKSQFLKYVEKTGQRAVYTTGKGASAVGLTAAVHKDPVTREWTLEGGALVLADRGICLIDEFDKMNDQDRVSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPVGGRYDSSKSFAQNVELTDPILSRFDILCVVKDVVDPVTDEMLAEFVVNSHFKSQPKGGKMEDSDPEDGIQGSSGSTDPEVLPQNLLKKYLTYSKLYVFPKLGELDAKKLETVYANLRRESMNGQGVSIATRHLESMIRMSEAHARMHLRQYVTEEDVNMAIRVLLDSFISTQKFGVQRTLRESFKRYITYKKDFNSLLLVLLKELVKNALKFEEIISGSNSGLPTIEVKIEELQTKAKEYDIADLRPFFSSTDFSKAHFELDHGRGMIKCPKRLITW
What is the function of this protein?
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.  May play a crucial role in the control of de-differentiation and cell proliferation processes required for lateral root formation.  Is essential for embryo development.  Is involved in the geminivirus mungbean yellow mosaic virus (MYMV) DNA replication, presumably in conjunction with other host factors.
What are the official names of this protein?
DNA replication licensing factor MCM2, Minichromosome maintenance protein 2, AtMCM2.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SELU_SALPK
Sequence: MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLKETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINAHQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQDVANWLKEQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: CRMC_ASPFU
Sequence: MAATTEKDLTARTTANIEAASDTVSLEEKSEREILERPNEITQDAQIGVQKAEATALVWSKTALYATYAWIWVCFFILNLQFSISNNMIYYAYAGFSSAPQISQAYILSTIIGGVLQLPIAKTLNLWGRAEGFLVFVGVLIVGIIVIASCNGPNGFAAGYTLYWIGYTAVNFILVVFVADASGLRNRAFAYAFIGTPTICTAFVGPLAAQAFYAHSTWRWAYGCFAIVIFFTFVPLALVFKFYQRKAEKTGVFVRDPSGRTPLQSFRHYFREFDLVGAFLLMAAFVLFLLPFSLETYGFSGYSSATFISMVVIGVLLFPVFAIWERFFAPTAFIKWQLFKNRTVLGACILAAVIFFNYYTWDQYYYYYLQVVYNLNTANTGYMTQIYSVGSTLWAVLFGIWIRQTKHFQKTCLYFGAPLMLLGAGLMIHFRGAESKIGYLVMCQIFIAFGGGTLVIGDEMAVMAAADRDGVPMMIAMISLAGSFGGAIGYAVAGAIYANTFPQALLRGLPDDLKGDSATVYLGGSTAQVMYPPGSAARNAINHAWTESQKYECITATAVVVLAFPAIAMWKNYNVDRKQVKGTVI
What is the function of this protein?
Major facilitator copper-regulated transporter; part of the crm gene cluster that mediates the biosynthesis of a yet unidentified copper-responsive metabolite.
What are the official names of this protein?
Major facilitator copper-regulated transporter crmC, Copper-responsive metabolite biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU5M_EPIFU
Sequence: MNLFTSTLILSLSMLTIPVLMSLSSIYKSTQYPYYVKTIISYAFFTSLIPTLIFINSGHEAILSNWHWMTIQTVKLSLNFKLDYFSMIFTPVALFVTWSIMEFSMWYMHSDPNMNRFFKYLLMFLITMMILVTANNLFQLFIGWEGVGIMSFLLIGWWYGRADANTAALQAILYNRIGDIGFILAMAWFLFNSNSWELQQIFMLDTNQNLLPLLGLLLAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLIRFYPLIETNKTMQTLILCMGAITTLFTAICALTQNDIKKIIAFSTSSQLGLMMVTIGINQPHLAFLHICTHAFFKAMLFMCSGSIIHNLNDEQDIRKMGGLYNALPFTTTSLIVGSLALTGTPFLTGFYSKDLIIETANTSYTNAWALLMTLIATSLTAVYSTRILYYSVLGQPRHSTLILINENNPLLINSIKRLLIGSIFAGFIISLNITPMTIPQMTMPTHLKLTALIITLTGFILALEISLMTQNLKLSYPHNYHKFSNMLGYFPIIMHRLIPSTTLMMSQKFSSMLLDLTWMENILPKSISNFQASSSIMVSNQKGLIKLYFLSFLITLIITMLLFNFHA
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FBX47_MOUSE
Sequence: MASRVNTSFTLIPKQKCRRSNHHSSYFCNTLDSDPQLLSTLGNFKVLPLEILHIILRYLSVKDIGMLSMVSKTVSQHIINYISTSSGSRRLLLQNFHDLDLPGTKEETALLEHYRALGLLFKRCTLLLPTKERLKYIHKILSEVSCFKFSGCSVPLQCLGLSCYGMFLQTLTAGWDELECHRVYNFLCELTNLSRKMQTVVCNKPGSARKLELRVRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPTSPHDGQVIWQEMIEGPTDESSLKGLANAIKLLYDTGAKGWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAVELARLVVFLALVCEKELYCMDWTVRMMQKVCKVFSTAAERKSFLQSIANAFACVTMEMLQPVMSGDRDDDDRGFLNLFHLLHAQANFHKEVLYLTMNAISS
What is the function of this protein?
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
What are the official names of this protein?
F-box only protein 47.
Protein: ZAPB_SHIB3
Sequence: MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQNAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: TACAN_HUMAN
Sequence: MQPPPPGPLGDCLRDWEDLQQDFQNIQETHRLYRLKLEELTKLQNNCTSSITRQKKRLQELALALKKCKPSLPAEAEGAAQELENQMKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILILISFTCRFLLNSRVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLAQDPQCKEWQVLMCGFPFLLLFLGNFFTTLRVVHHKFHSQRHGSKKD
What is the function of this protein?
Ion channel involved in sensing mechanical pain.  Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli (By similarity).  May also be required for efficient adipogenesis (PubMed:26024229).
What are the official names of this protein?
Ion channel TACAN, Transmembrane protein 120A, Transmembrane protein induced by tumor necrosis factor alpha.
What is the protein family that this protein belongs to?
Belongs to the TMEM120 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein.
Protein: TOT2B_HADIN
Sequence: MKFSKLSLTLALILTQAIFVLCGKINEDFMENGLESHALHDEIRKPIDTEKADAERGVVDCVLNTLGCSSDKDCCGMTPSCTLGICAPSVGGLVGGLLGRAL
What is the function of this protein?
Potent inhibitor of insect, but not mammalian, voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-hexatoxin-Hi2b, Omega-HXTX-Hi2b, Omega-atracotoxin-Hi2b, Omega-AcTx-Hi2b.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 15 family. 02 (omega-actx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPP2_STRAW
Sequence: MGSYTIPNVVERTPQGERSYDVFSRLLSERIIFLGTEIDDGVANVVIAQLLHLESANPEHEIAIYINSPGGSFTSLMAIYDTMTFVQAPISTFCVGQAASTAAVLLAGGDPGRRFVLEHARVLLGQPASGGRQGTVSDLSLQAKEMIRIRSQVEEVLSRHTRHDIATLRADMDRDKVFTAQEAVAYGLADEVLSRRLAVV
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.