PharMolix/UniProtQA huggingface dataset:
Protein: CASK_OVIMO
Sequence: VALINNQFLPYPYYAKPVAVRSPAQTLQWQVLPNTAPAKSCQDQPTTMARHPHPHLSFMAIPPKKDQDKTEIPTINTIASAETTVHSTPTTEAIVNTVDNPEASSESIVSAPETNTAQVTSTEV
What is the function of this protein?
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: SCX5_ANDCR
Sequence: VRDGYIMIKDTNCKFSCNIFKKWEYCSPLCQSKGAETGYCYNFGCWCLDLPDDVPVYGDRGVICRTR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Putative sodium channel alpha-toxin Acra5.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_SYNC1
Sequence: MSKRTYQPSRIRRKRTHGFRSRMQTKNGQAVIRRRRARGRKRLVVTIPVK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SYT_STAAT
Sequence: MEQINIQFPDGNKKAFDKGTTTEDIAQSISPGLRKKAVAGKFNGQLVDLTKPLETDGSIEIVTPGSEEALEVLRHSTAHLMAHAIKRLYGNVKFGVGPVIEGGFYYDFDIDQNISSDDFEQIEKTMKQIVNENMKIERKVVSRDEAKELFSNDEYKLELIDAIPEDENVTLYSQGDFTDLCRGVHVPSTAKIKEFKLLSTAGAYWRGDSNNKMLQRIYGTAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPMQLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDLHYDYARQLQDELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_BUCAI
Sequence: MNLIYNFSAGPAMIPRDVLNQAKKELHNWKNLGSSIMEISHRSEEFIQMALEAEKDLRDLLKIPDSFKVLFCQGGARGQFSAIPMNLLNNLQTADYINSGYWSNSAFMEAKKYCTPRSIFIRETNGVKESLLPMHKWNINENSAYIHYCPNETIDGLSIYEEPVFENKIVVGDFSSFILSRSINIKNYDLIYAGAQKNIGPAGITIIIIRKNIIGYSSKMTPSILDYKKISDHHSMFNTPPTFAWYLSGLVFKWLKKQGGLKAIEKLNKKKSDLLYKKIDNSDFYINKINSKHRSQMNVVFHLVNPKLNYIFLKEASKTGLNYLRGHSIVGGMRASLYNAMPLEGVESLVKFMSYFEKRYG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E1B55_ADE41
Sequence: MERPNPSVGGIYSGLHDNGPVENPAAEEEGLRLLAGAASARSGSSAGGGGGGGGGGEPEGRSGSSNGIVTEPDPEEGTSSGQRGEKRKLENDGADFLKELTLSLMSRCYPESVWWADLEDEFKNGNMNLLYKYGFEQLKTHWMEPWEDWELALNMFAKVALRPDTIYTIKKTVNIRKCAYVIGNGAVVRFQTFDRVVFNCAMQSLGPGVIGMSGVTFNNVRFAADGFNGKVFASTTQLTLHGVFFQNCSGVCVDSWGRVSARGCTFVGCWKGLVGQNKSQMSVKKCVFERCILAMVVEGQARIRHNAGSENVCFLLLKGTASVKHNMICGTGHSQLLTCADGNCQTLKVIHVVSHQRRPWPVFEHNMLMRCTMHLGARRGMFSPYQSNFCHTKVLMETDAFSRVWWSGVFDLTIELYKVVRYDELKARCRPCECGANHIRLYPATLNVTEQLRTDHQMLSCLRTDYESSDED
What is the function of this protein?
Plays a major role to prevent cellular inhibition of viral genome replication.  Assembles an SCF-like E3 ubiquitin ligase complex based on the cellular proteins ELOB, ELOC, CUL5 and RBX1, in cooperation with viral E4orf6.  This viral RING-type ligase ubiquitinates cellular substrates and targets them to proteasomal degradation: TP53/p53, LIG4, MRE11-RAD50-NBS1 (MRN) complex, ITGA3, DAXX and BLM.  Degradation of host TP53/p53 activity is essential for preventing E1A-induced TP53 accumulation that would otherwise lead to cell apoptosis and growth arrest.  E1B-55K also inactivates TP53 transcription-factor activity by binding its transactivation domain.  E1B-55K also functions as a SUMO1 E3 ligase for TP53 which causes the latter to be sequestered in promyelocytic leukemia (PML) nuclear bodies thereby contributing to maximal inhibition of TP53 function.
What are the official names of this protein?
E1B 55 kDa protein, E1B-55K, E1B protein, large T-antigen, E1B-495R.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1B 55 kDa protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Colocalizes with host TP53 to host PML nuclear bodies. PML localization of E1B-55K is necessary for E1B-55K-dependent SUMOylation of TP53.
Protein: MSRA5_ARATH
Sequence: MAISLKRNRFFIPYTNLVFFFFLCVSLLDKTVSIRISNQISDTVVDSPDRPLKSAVFALGSFWRSEAAFGCINGVVRTSAGYAGGTKTNPEYRNLGDHAESVQVEYDPRIIGYRQLLDVFWSSHDSRQVFGQGPDVGNQYRSCIFTNSTEELRLASTSKEREQLNTRSSIVTTQIQQLGTFYRAEPDHQKFELKQHPFLIQLIGNMVEEELERSALATKLNGYAAELCPPRIQKHIDSRVNEIIRKGWPVLRDI
What is the function of this protein?
Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins.  Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation.  MSRA family specifically reduces the MetSO S-enantiomer (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase A5, AtMSRA5, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase, Protein-methionine-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: GIH_HOMAM
Sequence: MVTRVGSGFSVQRVWLLLVIVVVLCGSVTQQASAWFTNDECPGVMGNRDLYEKVAWVCNDCANIFRNNDVGVMCKKDCFHTMDFLWCVYATERHGEIDQFRKWVSILRAGRK
What is the function of this protein?
Inhibits vitellogenesis in female animals.  Plays a prominent role in the regulation of reproduction/molting processes.
What are the official names of this protein?
Gonad-inhibiting hormone, GIH, Vitellogenesis-inhibiting hormone, VIH.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: MTGA_CROS8
Sequence: MSKTRGSLFVRLRRLALRAILAVLGVWIAGILLFSVMPVPFSAVMVERQFSAWFSGDFRYVAHSDWVSMDEISPWMGLAVIAAEDQTFPEHWGFDVAAIQKAVAHNENSRRIRGASTLSQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKRRILTVYLNIAEFGDGVFGVEEASQRYFNKPASRLSASEAALLAAVLPNPLRYKASAPSGYVRARQQWILRQMRQLGGEGFMAQHKLR
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ARLY_PELTS
Sequence: MTKLWGGRFQKETDRLVEDFHSSISFDRRLYKYDIRGSIAHARMLGKAGIIPPEEARAIADGLQEVLADIEAGRAGFSVEAEDIHMNVEQLLTAKVGEVGKKLHTARSRNDQVALDIRMYLKDEIDQITGLLRELQAALLDLAEKHTGTVMPGYTHLQRAQPVTLAHHLLAYCQMFRRDEERLADCRRRTDVMPLGAGALAGTTFPLDREYVAEQLGFAAVAENSLDAVSDRDFAVEFAAAASLIMVHLSRFCEEIVLWSSAEFAFIELDDAYSTGSSMMPQKKNPDVAELIRGKCGRVFGDLQALLTMLKGLPLAYNKDLQEDKEALFDAVDTVKKCLLVFKPMLETMQVKKERMAEAARGGFTNATDLADYLVRKGLPFRQAHEAVGKAVLYCLERGRSLDRLSLDELRQFSPLVEEDVYEAIDISRCVEARRVTGGPAPGAVLEAVKKARQRLRERP
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_SHIFL
Sequence: MNITATVLLAFGMSMDAFAASIGKGAPLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGSIIGKKAEILGGLVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDK_BRUC2
Sequence: MAIERTFSMIKPDATRRNLTGAIIAKLEEAGLRVVASKRVWMSRREAEGFYAVHKDRPFFGELVEFMSSGPTVVQVLEGENAIAKNREVMGATNPANADEGTIRKTFALSIGENSVHGSDAPETAAEEIAYWFSGTEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPF_LACE2
Sequence: MGMLDGLTNMFKMHDDDDFDDDYEDYDDDFDEDYEDDKPSARKRLFTGSSKKDSVADEEVSYTAEKPRFASKSKVVPMKTQSARGLEVVVIRPESMEDAKEITDTLLTGKAVVLNLEGIHVEIAQRIIDYSAGSTYAIRGNLQKITNYIFLVTPPNVDISGDIPEIVTGGIDLSSFNKNENRF
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RIMO_ACAM1
Sequence: MANQPSVAVAHLGCEKNRVDTEHMLGLLVEAGYPVDSDEAFADYVIVNTCSFIQAAREESVRTLVELAEANKKIVITGCMAQHFQEELLEELPEAVALVGTGDYHKIVDVIQRAEAGERVKEVSPEPTYIADETVPRYRTTTEGTAYVRIAEGCDYGCAFCIIPHLRGKQRSRSIESIVAEAQQLAAEGVQELILISQITTNYGIDLYGKPQLAELLRALGEVDVPWIRMHYAYPTGLTPEVMAAIQETDNVLPYLDLPLQHSHPEVLRAMNRPWQGQVNDQIIEKIKTALPDAVLRTTFIVGFPGETDEHFEHLCEFVQRHEFDHVGVFTFSPEEGTPAFDLPNQLPQDVMDARRDRLMALQQPISWQQNQQEVGKTVQVLIEQEHPGSGQLIGRSPRFSADVDGLVYIDPGEAPSPRLGSLTPVQITDADAYDLQGQLVSQ
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAA_BACCR
Sequence: MPIIIDKDLPARKVLQKENIFVMTKERAETQDIRALKIAILNLMPTKQDTEAQLLRLIGNTPLQLDVHLLHMESHLSRNVTQEHLTSFYKTFRDIENEKFDGLIITGAPVETLAFEEVDYWEELKHIMEYSKTNVTSTLHICWGAQAGLYYHYGVPKYPLKEKMFGVFEHEVCEQHVKLLQGFDELFFAPHSRHTEVRENDIREVKELTLLANSEEAGVHLVIGPEGRQVFALGHSEYSCETLKQEYERDRDKGLNIDVPKNYFKHNNPDEKPLVRWRSHGNLLFSNWLNYYVYQETPYIL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_STRPI
Sequence: MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNVLLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKS
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_SHEWM
Sequence: MTAQTIDGKAIAQSIRTQLKEKVTARKEAGKRVPGLAVILVGADPASQVYVGSKRRACEEVGFLSRSYDLESSTTEEQLLSLIDECNQDPAIDGILVQLPLPEHIEESKVIERIRPDKDVDGFHPYNVGRLAQRIPVLRSCTPMGIMTLIKSTGVDTYGLDALVVGASNIVGRPMSLELLLAGCTTTTCHRFTRNLEQKVRQADLVVVAVGKPGFIPGEWIKPGALVIDVGINRLEDGSLVGDVQYDVAAQNASFITPVPGGVGPMTIASLLENTLYAAEQYHDEA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HIP31_ARATH
Sequence: MSMTVEIRVPNLDCEGCASKLRKTLLKLKGVEEVEVEMETQKVTARGYRLEEKKVLKAVRRAGKAAELWPYRLGNSHFASFYKYPSYVTNHYYSDAHRTDPTGGVHTFFHTPADYSVAVAGDEIAASMFSDDNPHACTIM
What is the function of this protein?
Heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 31, AtHIP31.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: CPNE1_BOVIN
Sequence: MAHCVTLVQLSVSCDHLIDKDIGSKSDPLCVLLQDVGGGNWTELGRTERVQNCSSPEFSKTLQLEYHFETVQKLRFGIYDIDNKTPELGDDDFLGGAECSLGQIVSSRMLTLPLMLKPGKPAGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLAYRSEVIKNNLNPTWKRFSVPLQHFCGGDASTPIQVRCSDYDSDGSHDLIGTFHTSLAQLQAAPAEFECIHPEKQQKKKSYKNSGTICVKMCQVETEHSFLDYVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLTALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPFCAGIQGIVDAYRQALPQVRLFGPTNFAPIINHVARFAAQAANQRNASQYFVLLLLTDGAVTDVEATREAVVRASYLPMSVIIVGVGCADFEAMEQLDADGGPLHTRSGEAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQLVSYFRAQGWAPFKPPPPAAKGPAQAPQA
What is the function of this protein?
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes.  Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner.  Exhibits calcium-dependent phospholipid binding properties.  Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner.  May recruit target proteins to the cell membrane in a calcium-dependent manner.  May function in membrane trafficking.  Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit.  Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL.
What are the official names of this protein?
Copine-1, Copine I.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Note=Translocates to the cell membrane in a calcium-dependent manner.
Protein: MPK4B_PHYPA
Sequence: MDVAGAGGGGAADGNIQGVPTHNGEYTQYNIFGNLFEVSRKYVPPIRPIGRGAYGIVCSAVNSETGEEVAIKKIGNAFDNRIDAKRTLREIKLLRHMDHENIVAIRDIIRPPTRENFNDVYIVYELMDTDLHQIIRSNQPLTEDHCQYFLYQLLRGLKYIHSAKVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDVWSVGCIFMELLNREPLFPGRDYVQQLRLITELIGSPEDHDLGFLRSDNARRYIRQLPRFARQPLDRKFPNMGPAAIDLVEHMLRFDPARRITVEEALAHPYLATLHDINDEPICHSPFEFDFEQPSFTEEHIKELIMMEAIAFNPGNVGDMMS
What is the function of this protein?
The CERK1, MEKK1a/b, MKK1a/b/c and MPK4a/b proteins are involved in pathogen defense.  The pathway induces rapid growth inhibition, cell wall depositions and accumulation of defense-related transcripts.  This protein may act redundantly with MPK4a in innate immunity triggered by pathogen-associated molecular patterns (PAMPs).  May also be involved in resistance to necrotrophic fungi B. cinerea.
What are the official names of this protein?
Mitogen-activated protein kinase 4b, MAP kinase 4b, PpMPK4b.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: DNAK_STRMK
Sequence: MGKIIGIDLGTTNSCVAIMDGGKARVIENSEGDRTTPSIVAYTKDGEVLVGASAKRQAVTNPKNTFYAVKRLIGRKFTDAEVQKDIAHVPYSILAHDNGDAWVATSDGKKMAPQEISAKVLEKMKKTAEDFLGEKVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKGDNKDRKIVVYDLGGGTFDVSVIEIANVDGEKQFEVLATNGDTFLGGEDFDNRVIEYLVEEFNKDQGIDLRKDPLALQRLKDAAERAKIELSSAQQTEVNLPYVTADASGPKHLNIKLTRAKLEALVDDLIKKSIEPCRVALNDAGLRSSDISEVILVGGQTRMPKVQQAVTEFFGKEPRKDVNPDEAVALGAAIQGGVLGGDVKDVLLLDVTPLSLGIETMGGVFTKIIEKNTTIPTKASQVFSTAEDNQSAVTVHVLQGEREQARFNKSLAKFDLSGIEPAPRGLPQVEVSFDIDANGILHVSAKDKKTNKEQKVEIKAGSGLSEEEIARMVADAEANREEDKKFQELVQARNQADALIHGTRSAITEHGSKVGGDVIGKVEAALADLETAMKGDDKAQIEAKSKALEEAGQSLFAAASADQGGAPGADAGNAGKAQDDVVDAEFTEVKDDKKS
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MALT_ESCF3
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLVSQWAAGKSELGWFSLDEGDNQQERFASYLIAAIQQATNGHCTASEVMAQKRQYASLSSLFAQLFIELAEWHQPLYLVIDDYHLITNPVIHESMRFFLRHQPENLTLVVMSRNLPQLGIANLRVRDQLLEIGSQQLAFNHQEAKQFFDRRLTSPIEAAESSRMCDDVSGWATALQLIALSARQNSHSAHQSARRLSGINASHLSDYLVDEVLNNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDSGEWFSYHPLFGNFLRQRCQWELAAELPEIHLAAAESWMAQGFPSEAIHHALAAGDASMLRDILLNHAWGLFNHSELALLEESLKALPWESLLENPRLVLLQAWLMQSQHRYSEVNTLLARAEQEIKGEMTGTLHAEFNALRAQVAINAGNPEEAERLARLALDELPIAWFYSRIVATSVHGEVLHCKGDLSRSLALMQQTEQMARHHDVWHYALWSLIQQSEIYFAQGFLQAAWETQDKAFQLIKEQHLEQLPMHEFLVRIRAQLLWAWSRLDEAEASARSGIEVLSSFQPQQQLQCLALLVQCSLARGDLDNARTLLNRLENLLGNGQYHSDWISNADKVRVIYWQMTGDKKAAANWLSQTPKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARQLRLMSDLNRNLLLLNQLYWQAGRKNDAQRVLMEALQLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: VM23A_ECHCA
Sequence: NSVHPCCDPVKCEPREGEHCISGPCCRNCYFLRAGTVCKRAVGDDVDDYCSGITPDCPRNRYKGKED
What is the function of this protein?
Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1).  It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins.  The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit.  The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B.
What are the official names of this protein?
Disintegrin EC3A.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIe sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RF1_BACMK
Sequence: MLDRLQAVENRYEKLNELLSDPEVISDTNKLREYSKEQSDIQDTVEVYREYKDVREQLRDAKAMLEDKLDADMRDMVKEEVSELEGQEKTLSERLKILLVPKDPNDDKNVIVEVRGAAGGDEAALFAGDLYRMYSRYAEVQGWKTEIIEASYTELGGYKEIIFMINGKGAFAKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEAEEVEINIHEKDVRVDTFASSGPGGQSVNTTMSAVRLTHLPTGVVVSCQDEKSQIKNKEKAMKVLRARVYDKFRQEAQAEYDQNRKQAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILQGKLDDFINALVMEDQAQKMEAAE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_STAA3
Sequence: MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PHAB_CUPNH
Sequence: MTQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGADFSLNGGLHMG
What is the function of this protein?
Catalyzes the chiral reduction of acetoacetyl-CoA to (R)-3-hydroxybutyryl-CoA.  Is involved in the biosynthesis of polyhydroxybutyrate (PHB), which is accumulated as an intracellular energy reserve material when cells grow under conditions of nutrient limitation.
What are the official names of this protein?
Acetoacetyl-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROBK_OLEEU
Sequence: MSWQTYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-3, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FAR1_BRUPA
Sequence: MYHRLILLALVGTTMANVIPFSMNNIPEEYKEFIPEEVRNFYKDLTVEDKEILRELASKHATFANEDAALEALKDKSDKLYKNAVELRNFVKAKIDSLKPDAKIFVDEIIAKARSLRSDDGHKLDTEKIKQAARDIIAKYQALSEETKEELKVTFPAIAKIIGNEKLKRNASTFLQKN
What is the function of this protein?
Binds retinol and different fatty acids.
What are the official names of this protein?
Fatty-acid and retinol-binding protein 1, Bp-FAR-1.
What is the protein family that this protein belongs to?
Belongs to the fatty-acid and retinol-binding protein (FARBP) family.
What are the subcellular locations of this protein?
Secreted.