PharMolix/UniProtQA huggingface dataset:
Protein: PROB_AFIC5
Sequence: MSHSDLRLTDFRRIVIKVGSSLLIDSAAGKVKSAWLAALADDIAALHRAGKDVLVVSSGSIALGRSRLKLPSGTLKLEESQAAAAVGQIALARIWAKVLDHHGIGAGQILVTLRDTEERRRYLNARSTISKLLEWRAVPVINENDTVATSEIRYGDNDRLAARVATMTSSDLLILLSDIDGLYTAPPGINPNAKLIPVVESVTADIEAMAGAAGSELSRGGMRTKIEAAKIATSAGTHMLIASGKIDHPLQAIIDGGPCTWFLTPANPVTARKRWIAGSLEPKGVLVIDAGAVKALDAGRSLLAAGVTRIEGTFARGDAVVVRGPDGHEIGRGLVAYSADNAERIKGKSSAAASKILGLTGRPEMIHRDDLVVSHHHDNGHNNGSHGVSTPAPEPSA
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON2_SYMTH
Sequence: MPGVVSWSQLVNPSYVAILPHLIVTATLLVVIVLDAYFKEKRSLVWVTLGGVVLAMLSIWYTASDPQIQAGIAAGRPPEFWGGMIIADGFTFFMNGVLLGIAALVILLSADYVGKFLRGAHMEFYEIILAVTLGMMFMVSSRDLLTIYIGLELTSISSYVLAGILRKDAKSNEAALKYFLTGATASAVLLFGLSLIYGVTGSTRLPEVAAALAGGSHVVAAAGPALTPLLVAGMAFLMVGFGFKVAAVPVHQWAPDVYEGAPTPVTAFFSAGPKGAAMAAILRVFVGGLGVAPFTDKWALIWALAAAASMTVGNLVALQQTNIKRMMAYSSIAQAGYILVGVAASGLQSVEGISSVLFYVMAYAVTNLGIFAVLTHMDQEGGWVEVDNYAGLAKRNPLYAWALLLFFVSLIGIPPTVGFLGKFFLFRAAAASGYLWLAVLMAVNSVISVGYYYRVVKVMFLDQSDYPALTPSTGISATVLLSLLGVVALTIFANPFVQWTAQSAALLH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 2, NADH dehydrogenase I subunit N 2, NDH-1 subunit N 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRP3_KLULA
Sequence: MAKIEKKQAVKNNQVLSLAEKIKRKALEKQQQAHANEPSPSDEDSAQSNSKDSNSNEQPEESEEIFESFTELDLVPELIEACKNLNYNKPTPIQSKAIPPALKGSDIIGLAQTGSGKTAAFAIPILNQLWHDQQPYYACILAPTRELAQQIKETFDSLGSLMGVRSTCIVGGMSMMDQARDLMRKPHIIIATPGRLMDHLENTKGFNLRKLKYLVMDEADRLLDMEFGPVLDRILNIIPTQGRTTYLFSATMTSKIDKLQRASLTNPVKCAVSNKYQTVDTLVQTLMVVPGGLKNTFLIYLLNEFIGKSTIVFTRTKANAERISNLCNLLEFSATALHGDLNQNQRTGALDLFKAGKRSILVATDVAARGLDIPSVDIVINYDIPVDSKSYIHRVGRTARAGRSGKSISLVSQYDLELILRIEDVLGKKLPKENVDKDAILALRDSVDKANGEVVMELNRRNKEKQARGKGRRGRMATRDNMDREER
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase RRP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FMNR_SCHPO
Sequence: MTLPEKLLKITPKILVIMGSVRSKRLCPTIATWVGEMGKRETNFDYEKVDLTDWPLSMSDEPGLPIMGIDVYTQEHTKAWGSKIAGADGFVFVTPQYNGGYPAILKNALDHLYHEWNGKPLLIVSYGGHGGGDCASQLKHVAGFLKMRVAPTMPALTLPRDKIVQGVVDPAVEFTKHLGELKKAFGEFSQLFESNPERKP
What is the function of this protein?
Has several reductase activities that are NAD(P)H-dependent and involve FMN as a cofactor.  May be involved in ferric iron assimilation (By similarity).
What are the official names of this protein?
NAD(P)H-dependent FMN reductase C4B3.06c, FMN reductase C4B3.06c, Azoreductase C4B3.06c, FMN reductase [NAD(P)H].
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KU_MYCS2
Sequence: MRSIWKGSIAFGLVNVPVKVYSATEDHDIKFHQVHAKDNGRIRYKRVCEVCGEVVEYRDINKAFESDDGQMVVITDEDIATLPEERSREIEVVEFIPAEQLDPLMYDKSYFLEPDSKSSKSYVLLAKTLAETDRIAIVHFSLRNKSRLAALRVKDFSKRDVMMIHTLLWPDEIRDPDFPILDKEVQIKPAELKMAGQVVESMTDDFKPDLYHDDYQEQLRELVQAKLEGGEAFSVEEQPAELDEGTEDVSDLLAKLEASVKARKGGKSDSKDDSDSESDSKESKSDSKPAKKAPAKKAAAKKSTAKKAPAKKAAAKKS
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) repair enzyme which repairs blunt-end and 5'-overhang double strand breaks (DSB) with about 50% fidelity, and DSB with non-complementary 3' ends.  Plays a partial role in NHEJ on 3'-overhang repair of complementary ends.  NHEJ repairs DSB with blunt ends and 5' overhangs with a high level of nucleotide insertion/deletion, without a need for microhomology.  This protein but not LigD also suppresses homologous recombination.  Overexpression dramatically increases the efficiency of NHEJ with no effect on repair fidelity.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: VG03_EHV1B
Sequence: MGACCSSRRNRSPSLAALAEETEVVLRCLAGRVVDLPGGDEVRIAPDVGRPGQNFGYFKFPGPSRFAYVKFIGRAYALGSGRKFLLYLSRNFQVFGYEDGTGLHMLAKSLHDFLKFKGLSDRDLVVVDSVALTSQLRPLTLPIRSTSDVETLVAEEATTNYTSTENLLGQTQSSTHRPLGVPLSNVKTMGVPPTKPSSQRPRGKGGRPPARLKSIREETVSGMARAREECNSPSEHDRLTSEMTDCDSDSSVSSVFF
What are the official names of this protein?
Gene 3 protein.
Protein: SFSA_BRUSI
Sequence: MLFPTPLISGRLERRYKRFLADVTLDDGRFITASVPNTGSMLGLTAPGSRVWLSFSDAPHRKYAHTLQIVEADNTLVGVNTGLPNRIAEEAILKGLIPDLDGYATLKREQKYGRNSRIDLLLDDGPRPRAYVEVKNVHFIRTPGLAEFPDTVTARGAKHLDELVDVVAAGHRGIMLFIIQRADCSRFGISGDLDPFYARAFERAIASGVEAWAVRCHITENGIDATELVPIEDMRRIE
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RS17B_CANAL
Sequence: MGRVRTKTVKRASKVLIERFYPKLTLDFETNKRLTSEIAVIQSKRLRNKIAGYTTHLMKRIQKGPVRGISFKLQEEERERKDQYVPEVSALDLSHTNGQLEIDADTADLVKSLGFKIPVQTVSISAQRGPRRFAKRN
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S17B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: YIDC_SALG2
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQTQQTTQTTTTAAGSAADQGVPASGQGKMITVKTDVLDLTINTRGGDVEQALLPAYPKELGSNEPFQLLETTPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQNELQVPMTYTDAAGNTFTKTFVFKRGDYAVNVNYSVQNAGEKPLEVSTFGQLKQSVNLPPHRDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNVSSKGGWVAMLQQYFATAWIPRNDGTNNFYTANLGNGIVAIGYKAQPVLVQPGQTGAMTSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYR_PHOV8
Sequence: MNIEEKLTTSIISAIKTLYGQDVPGKMVQLQKTKKEFEGHLTLVVFPFLKMSKKGPEQTAQEIGGYLKEHAPELVSAYNAVKGFLNLTIASDCWIELLNSIQAAPEYGIEKATENSPLVMIEYSSPNTNKPLHLGHVRNNLLGNALANVMAANGNKVVKTNIVNDRGIHICKSMLAWLKYGNGETPESSGKKGDHLIGDYYVAFDKHYKAEVKELTAQYQAEGLNEEEAKAKAEANSPLMLEAREMLRKWEANDPEIRALWKKMNDWVYAGFDETYKMMGVSFDKIYYESNTYLEGKEKVMEGLEKGFFYRKEDNSVWADLTAEGLDHKLLLRGDGTSVYMTQDIGTAKLRFQDYPINKMIYVVGNEQNYHFQVLSILLDKLGFEWGKGLVHFSYGMVELPEGKMKSREGTVVDADDLMEAMIETAKETSAELGKLDGLTQEEADNIARIVGLGALKYFILKVDARKNMTFNPKESIDFNGNTGPFIQYTYARIQSVLRKAAEAGIVIPEIIPAGLELSAKEEGLIQMLADFKSVVKQAGSDYNPSIIANYAYDLVKEYNQFYHDFSILREENEALKVFRLALSANVGKIVKTAMGLLGIEVPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIA_PANPA
Sequence: MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
What is the function of this protein?
Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (By similarity).  Activates endothelial cells (ECs) in a proinflammatory manner by stimulating activation of NF-kappa-B and ERK, JNK and p38 MAP-kinases and by inducing expression of adhesion molecules including SELE and VCAM1 (By similarity).  Induces apoptosis in ECs by promoting the FOXO1-dependent expression of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity).  In response to oxidative stress, initiates proapoptotic and antiapoptotic signaling in ECs via activation of NF-kappa-B and AKT1 and up-regulation of antiapoptotic protein BCL2 (By similarity).  Negatively regulates MAP3K5/ASK1 kinase activity, autophosphorylation and oxidative stress-induced apoptosis mediated by MAP3K5/ASK1 (By similarity).  Necessary for the assembly of TARDBP in heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and regulates TARDBP binding to RNA UG repeats and TARDBP-dependent expression of HDAC6, ATG7 and VCP which are involved in clearance of protein aggregates (By similarity).  Plays an important role in platelet activation and aggregation (By similarity).  Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (By similarity).  Binds heparan sulfate glycosaminoglycans (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Nucleus. Note=Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.
Protein: ALG1_DICDI
Sequence: MNRVAVVVLGDIGRSPRMQYHSMSLSKLENTKVTLIGYRESEPHPQIVNNDSITIEPLKPFPISMSNSFKKIPLISIFMWPLLAICKVLFQIIQLMYVLLVKVPSPLNTILVQSPPAIPTIFVMQIVCWIRGVHLVIDWHNLGYTLLKLSLSKSDNHPIIRLAKFIERYFAKNAYAHLFVTNEMKIQLVRDWNLKGKTFVFHDKASPIFKSLTDREQEEFLKTFINKYSIKGEDKVYIESVISKKSIRNPKQQTSIIISSTSWTQDEDFSILLDAIVKYDIEHAINNNNNKVEEAQDESVVLAENLLFIITGKGPQKEYYQEKINSLSLKKSRIITVWLDSEDYPKLLACCDLGVSLHNSSSGIDLPMKVVDMFGCCLPVLAIDFKCIGELVKVNYNGFLFKDSDQLHQLLNQLFTHPTNNNTITNTNNNKNLILEKMRKNLTKDRETDTWESNWLTIKPLFIPSSSSSSSSSSSSSSSSSSSSSSNSKSKKD
What is the function of this protein?
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation.  Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.
What are the official names of this protein?
Chitobiosyldiphosphodolichol beta-mannosyltransferase, Asparagine-linked glycosylation protein 1 homolog, Beta-1,4-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: LON_KARMG
Sequence: MLLHETESEYDSKSKKNNYSYYESSDFKPLIEKYNRIKYSVTEYIYLLTVKNVVLFPDVVIPITAVKQKSINLFKSAYYTYKKIGILTKKYFNTTFSIAKLNIQTFNIYSFNKFNKINKFNKINKFNKINKFNKINKFNKINKFNKTNNIYYIGTVAKILKLLIMPDGNTTVILQGISRFKIIKLIQVYPYFKAEIIYLKDEKPQKKDKEYLILIDSIKEIAIKIIQDNYKIPSESSFAISNIESKSFLINFVAYNLNIEIKNKQILLEYDFLKQRAIETFRFLNIEYEKIKLKNDIQYRVRYDIDQQQKEYFLNQQIKALQEELGDFSYEKEVEVLRIKSYKKNWSKEAQNQFDRELSKLKRTNPQMPEYTILRNYLDLMLDLPWKKYSQDNYDLYRAQKILDKDHFGIDKVKERIIEYLSVLKLKGDLRSPILCFYGPPGVGKTSLGRSIASALNRKYVRISLGGLNDEAEIRGHRKTYIGAMPGRVLQSIKKAGTSNPVFVLDEIDKMGLGSQGNPSSAMLEVLDPEQNKEFYDNFLEMGYDLSKVIFIATANSLYTINIALLDRMEIIDMNGYTVEEKIEISKKHLIPKQLKENGLKSKDIILGVKQIEKIIESYTRESGVRSLEKNISKIVRYAAKNIAMNKKYLKRINMSKIEEVLGPPNDPEKYELIQVPGVVTGLAWTIVGGEIIYIESTLLKGRGNLSITGNVGEVMKESATIAFKYIKAHNYEFGIDEKMFELYNIHIHAPEGGIHKDGPSAGITMLTSIISSFLKKKIRPYLAMTGEITLRGKVLPVGGIKEKILAAKRANIKEIILSKANKKDIDDIKKVYLKGLKFHFVSKMNEVIDLSIIK
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
Protein: WASF1_RAT
Sequence: MPLVKRNIDPRHLCHTALPRGIKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVTQLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNVLTPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRPHEPEKVPRAPHDRRREWQKLAQGPELAEDDADLLHKHIEVANGPASHFETRPQTYVDHMDGSYSLSALPFSQMSELLSRAEERVLVRPHEPPPPPPMHAAGDARPTPTCVSSAAGLIENRPQSPAAGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPAPALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVAALAHPPSGLHPTPSPAPGPHAPLMPPSPPSQVLPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDWLE
What is the function of this protein?
Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.  Promotes formation of actin filaments.  Part of the WAVE complex that regulates lamellipodia formation.  The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity).  As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).  Also involved in the regulation of mitochondrial dynamics (By similarity).
What are the official names of this protein?
Actin-binding protein WASF1, Protein WAVE-1, Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1.
What is the protein family that this protein belongs to?
Belongs to the SCAR/WAVE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Synapse. Cell junction, focal adhesion. Note=Dot- like pattern in the cytoplasm. Concentrated in Rac-regulated membrane- ruffling areas. Partial translocation to focal adhesion sites might be mediated by interaction with SORBS2. In neurons, colocalizes with activated NTRK2 after BDNF addition in endocytic sites through the association with TMEM108 (By similarity).
Protein: PDXT_BACC0
Sequence: MVKIGVLGLQGAVREHVKSVEASGAEAVVVKRIEQLEEIDGLILPGGESTTMRRLIDKYDFMEPLRTFAKSGKPMFGTCAGMILLAKTLIGYDEAHIGAMDITVERNAFGRQKDSFEAALSIKGVGEDFVGVFIRAPYVVDVADDVEVLSTHGDRMVAVRQGPFLAASFHPELTDDHRVTAYFVEMVKEAKMKKVV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DF203_ARATH
Sequence: MAKLIVNFSALLMIILLVSNGLPKAVAQTCFKGEAQEGVCVKVDGSKLCDLLCRATNTTWFGACEVEDNETHCHCYGPC
What are the official names of this protein?
Putative defensin-like protein 203.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_EHRRW
Sequence: MEGNIVSGKAVADNITNILATCISDLKAQHNLTPCLIVVLVGDDPASQLYVRNKQRKAEMLGLRSETMLLPSTISESSLIEKIHQLNNDDSVHGILVQLPVPRHIDKNLIINTIDPKKDVDGFHNENVGRLFTGQKKNCLVPCTPQGCLYLIKTITRNLSGSDAVVIGRSNIVGKPMACLLLGENCTVTTVHSATRDLPDYCRRADILVAAVGIPRFVKYSWVKHGAIVIDVGINSIEEDGVKKFVGDVDFAEVNKIASAITPVPGGVGPMTIAFLMVNTIIAACNQSGIDGFLEKYLDL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: FTSZ_HALMT
Sequence: MDSIVDDAIDEAEDMGDGSAEVGGPTDINRSGTMTDDELQAVLKDLQTNITVVGCGGAGGNTVNRMHEEGIKGAKLVAANTDVQHLVEIGADTKILMGEQKTQGRGAGSLPQVGEEAALESQEEIYDAIEGSDMVFVTAGLGGGTGTGSAPVVAKAARESGALTIAIVTTPFTAEGEVRRTNAEAGLERLRDVSDTVIVVPNDRLLDAVGKLPVRQAFKVSDEVLMRSVKGITELITKPGLVNLDFADVKTVMERGGVAMIGLGESDSESKAQESVKSALRSPLLDVDISGANSALVNVTGGSDMSIEEAEGVVEEIYDRIDPDARIIWGTSVDDELEGMMRTMIVVTGVESPQIYGRNGEVQAQAEGRLEDIDYVE
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: UBIA_PSEP1
Sequence: MYLQLLKSLNRLHPRAWDFVQLSRMDRPIGIYLLLWPTLSAVWIAGNGSPTLANVLIFGLGVVLMRAAGCCINDFADRKVDGHVKRTADRPLASGRVRPREALTLFAILVGVSFLLVLCTNSRTVWLSFGAVALAFCYPFMKRYTYYPQVVLGAAYSWGIPMAFTAAGGELPAGAWLLYIANLLWTVGYDTYYAMVDRDDDLKIGVKSTAILFGDADRSIILTLQLLSLGCLLLAGSRFDLGGWFHLGLLGAAACFAWEYWSTRKLDRESCFKAFLHNHWAGMLVFIGVVLDYALR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTS2_POSPM
Sequence: MLAARFASRAFPRTRLYSTAPKRSLKELVTELRSQADVSPIQAGQALKASDMDVSKALLWLEKQRTQSAVKKAAKVADRTANEGLIGTTVLSSGVANGRRVGVRAAMVELNCETDFVARNELFANLLEDITHTAAFISEPANAETFMQPFSMETLQNAPLLSQTKPSQNGKATVSEAMRDLTGRVGEKISLRRALTVVRDPFTSSQPDLALRVAARVHQSVFNPTQGRIGSLALLALKSKRLSEAIASQTFQDDLDKLCQALGRQVIGFPTTCIRSPPGTTDEGALYDQPFSMFIGPGNDQSVGAFLQSWAQERSLVNKDEEQSAGVEVLEFAKWTVGDVV
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial 2, EF-Ts 2, EF-TsMt 2.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GET1_YARLI
Sequence: MDEAIIVDAEFVAPVGTTAGEFVPIDRAPAAGLLLLVAFVVLYAKVISKLGKPAIQEFLWEIITRIVPSKQLRRRKEAQLRAIEVHTQRSNTSSQDQFAKWAKLDREYGKLKVEIEDINNLLTASKARFFTIISSAIFLSTTGMKMFLRIKHRKAAIFWLPKNAFPYPIEYILSFSSAPLGSVSVSAWLMICDAAMDLIVTIFVALVVGVIGMLRSNKVKPKTA
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RL1_BURM1
Sequence: MAKISKRRQAFAAKVDRQKLYAIDDALALVKECASAKFNESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEVVGMEDLAEQIKAGQMDFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEPAALRSNLSALIEALQKAKPATSKGVYLRKIALSSTMGVGVRVDQATLAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: GLGA_ECO24
Sequence: MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.