PharMolix/UniProtQA huggingface dataset:
Protein: HSCA_CUPTR
Sequence: MALLQISEPGMSPAPHQRRLAVGIDLGTTNSLVAAVRSSIPEVLADERGRALLPSVVRYLPDRTAQIGYRAQDEAVRDPKNTIVSVKRFMGRGLRDVANIEHSPYDFVDAPGMVQIKTAAGVKSPVEISAEILATLRQRAEDSLGDDLVGAVITVPAYFDEAQRQATKDAARLAGLEVLRLLNEPTAAAIAYGLDNAAEGIYAVYDLGGGTFDISVLKLTQGVFEVLATGGDSALGGDDFDQRLLCWIVEQANLQPLSAQDMRLLMVRARAAKEALSEADSTVIDAVLESGEIVHLTLTDEIFEQITAHLVQKTLAPVRKALRDAGVGPEEVKGVVLVGGATRMPSIRKAVGDFFGQNPLTNLDPDRVVALGAAMQANLLAGNHAPGEDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIPVARAQEFTTFKDGQTAMAIHVLQGERELASDCRSLARFELRGIPPMVAGAARIRVTYQVDADGLLSVTARETHSGVEASVTVKPSYGLADDDIARMLQDSFREAEHDMKSRALAEERVEADRLVEATQRALETDGDLLSADERAAVEALMATVREIATGEDHLAIRAAVEKLSHGTDEFAARRMDRSIKSALAGRKVQELG
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL4_BRUMB
Sequence: MDLTITTLEGKDAGKVKLNEEIFGLDPRDDILQRVVRWQLARRQQGSHKAQGRGDVSRTGSKMYKQKGTGRARHHSARAPQFRGGGQAHGPVVRNHDHDLPKKVRALGLRHALSAKAKASDLIIIDDLASADAKTKQLVSQFAKLGLENALLIGGAEIDANFQRAASNIPNIDVLPVQGINVYDILRRGKLVLSKAAVEALEERFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: EX7S_STRPQ
Sequence: MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKELQKTLQAAEKTLVKVMQADGTEVDMDD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_PARL1
Sequence: MTLKARLIPCLDVKDGRVVKGVNFVDLRDAGDPVEAARAYDAAGADELCFLDITASHEERAIIFDVVRRTAEQCFMPLTVGGGVRTIEDVRQLLLAGADKVSIMTAAVFNPDFVKAAAEKFGNQCIVVAIDAKQTGPGKWEIFTHGGRKPTGIDAVEYAVKVCELGAGEILLTSMDRDGAKSGFDIALTRAVADAVPVPVIASGGVGTLDHLVEGIRDGHASAVLAASIFHFGEFTIGEAKAHMAEAGLPIRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_LIGS1
Sequence: MVNRLKEKYDNEIVPSLMEKFNYTSIMQAPKVDKIVINMGVGDAVSNAKRLDEAVDELTLIAGQKPVITKAKKSIAGFRLREGMAIGAKVTLRGQRMYEFLDKLVSVSLPRVRDFHGVSKRAFDGRGNYTLGIREQLIFPEIDFDDVNKVRGMDIVIVTTANTDEESRELLTQLGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SECY2_STRGC
Sequence: MKSFFKPLILKKFLWTLLFVFIYVLGSKLTLPFVDVSSIAKLNGDSVTLNYAAALMGGNLRSMSFFSIGLAPWMSSILIWQMFTVSKRLGFNKLSMESQEKRRMLLTLAIALIQSLALVLNLPLKTVVGVGQGTIVFLNTLILIAGTYFLIWLTDLNSSMGLGGSIMIVMVSMISYIPQDIWLSIQELKISPLILALIGFFSLCFLYLAVLVERAKYRIPINKINIHNRFKKYSYLDIRVNAAGGLPIMYAMTLVSIPQYFLMLFLFFQPNNRLLKEGILSLAMGGIPWFILYLLTIFILAWAFAFINVNSDQIAERMQRSGEYIENLYPGEATRRYIHKIVGYFAFVGALYLVLVAGLPMLLIFLDIRYMRLGMIPGMFMIFIGMVFSIKDEVDTLTLNDRYRSLF
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins.  The central subunit of a protein translocation channel.
What are the official names of this protein?
Accessory Sec system protein translocase subunit SecY2.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SWI6_YEAST
Sequence: MALEEVVRYLGPHNEIPLTLTRDSETGHFLLKHFLPILQQYHDTGNINETNPDSFPTDEERNKLLAHYGIAVNTDDRGELWIELEKCLQLLNMLNLFGLFQDAFEFEEPETDQDEEDPSHSKLPENKTKSENSKDNISSKRINNLQDMSLDSDAHRELGSPLKKLKIDTSVIDAESDSTPNTARGKPNDDINKGPSGDNENNGTDDNDRTAGPIITFTHDLTSDFLSSPLKIMKALPSPVVNDNEQKMKLEAFLQRLLFPEIQEMPTSLNNDSSNRNSEGGSSNQQQQHVSFDSLLQEVNDAFPNTQLNLNIPVDEHGNTPLHWLTSIANLELVKHLVKHGSNRLYGDNMGESCLVKAVKSVNNYDSGTFEALLDYLYPCLILEDSMNRTILHHIIITSGMTGCSAAAKYYLDILMGWIVKKQNRPIQSGTNEKESKPNDKNGERKDSILENLDLKWIIANMLNAQDSNGDTCLNIAARLGNISIVDALLDYGADPFIANKSGLRPVDFGAGTSKLQNTNGGDENSKMVSKGDYDGQKNGKAKKIRSQLLKNPPETTSLINDVQNLLNSISKDYENETVQYNEKLEKLHKELNEQREELANSREQLANVKQLKDEYSLMQEQLTNLKAGIEEEEESFREESKKLGIIADESSGIDWDSSEYDADEPFKVEFLSDFLEDKLQKNYEGDISKLLEAESKEQIMEQIRNQLPAEKIQSMLPPTVLLKARINAYKRNDKHLTNVLDTISTKQSELENKFRRVLSLCLKIDENKVDNMLDGLLQAISSEDPQDIDTDEMQDFLKKHAS
What is the function of this protein?
Part of a complex involved in cell-cycle-dependent transcription.  SWI4 and SWI6 are required for formation of the cell-cycle box factor-DNA complex.  The repeated element in the upstream region of HO (5'-CACGAAAA-3') is called the cell cycle box (CCB).
What are the official names of this protein?
Regulatory protein SWI6, Cell-cycle box factor subunit SWI6, MBF subunit P90, Trans-acting activator of HO endonuclease gene.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NS1_INCY6
Sequence: MSDKTVKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLRTESSFAPRTWEDAIKDGELLFNGTILQAESPTMTPASVEMKGKKFPIDFAPSNIAPIGQNPIYLSPCIPNFDGNVWEATMYHHRGATLTKTMNCNCFQRTIWCHPNPSRMRLSYAFVLYCRNTKKICGYLIAKQVAGIETGIRKCFRCIKSGFVMATDEISLTILQSIKSGAQLDPYWGNETPDIDKTEAYMLSLREAGP
What is the function of this protein?
Prevents the establishment of the cellular antiviral state initiated by host RIGI, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors IRF3 and IRF7.  Participates also in the up-regulation of the splicing of viral mRNAs.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza C viruses NS1 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: YR579_MIMIV
Sequence: MVVQYLLFSNDKNVDPTNLVLRQDFLHQKCLLISVSNSSHIFHEMLSFRNVRKDDFIIEFFSENNVCSLDNCIAKKIHYLSDINTFDMLLSLDGEYESLIKWFISVNYFEALQNYQHLVKSLSLKTDLMFYAVSKNVSIDVINFLIDMDCKCTIDSITRAIAEKKLDIAKIIIDHNPSENIIHESLYCLSYEKQKDLFKYVLENYKIDSRYYHKSLIYWMINKDEEIMCDLLCRIDIKEFSKEKNISSYVIQSNSLNVVKTFVEHGLQFNPDIYLWVNGNSESENIVRYIIELGIDYRPHIDRLLKICITSGTFSHLEYLINLGVSQENINEAFLTAVSEDKFELIKYLIYMGADINYKNTIAASYTDNIDVLKYLIEKGADITTGGSNDVINHAIGSHQSDFCRCLLENGATITLDDRDELMVIYRELTNGCSYEDDDYEDLDQLTNSDLRNLIHEEIMNSC
What are the official names of this protein?
Putative ankyrin repeat protein R579.
Protein: INCA_CHLCV
Sequence: MTVSTDNTSPVISRASSPTFGDHGKDFDNNKIIPISIEAPTSSAAAVGAKTAIEPEGRSPLLQRICYLVKIIAAIALFVVGIAALVCLYLGSVISTPSLILMLAIMLVSFVIVITAIRDGTPSQVVRHMKQQIQQFGEENTRLHTAVENLKAVNVELSEQINQLKQLHTRLSDFGDRLEANTGDFTALIADFQLSLEEFKSVGTKVETMLSPFEKLAQSLKETFSQEAVQAMMSSVTELRTNLNALKELITENKTVIEQLKADAQLREEQVRFLEKRKQELEEACSTLSHSIATLQESTTLLKDSTTNLHAVESRLIGVMVQDGAESSTVEEASQDDSAQPQDENQSDAGEHKDS
What is the function of this protein?
Chlamydia replicate within a host intracellular vacuole, termed an inclusion, which is formed by fusion of many smaller inclusion bodies.  IncA is probably involved in the homotypic fusion of inclusions.
What are the official names of this protein?
Inclusion membrane protein A.
What is the protein family that this protein belongs to?
Belongs to the IncA family.
What are the subcellular locations of this protein?
Secreted. Host vacuole, host pathogen-containing vacuole, host pathogen-containing vacuole membrane; Multi-pass membrane protein. Note=Secreted, probably by a type III secretion system (By similarity). Localized in the inclusion membrane (Probable). In the inclusion, the C-terminus faces the host cytosol (Probable).
Protein: HIS2_BURP1
Sequence: MTQSTTEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAILKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLVALSHFDLSPADVIAELERREGMSGIEEKALRKRREREENGG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6967_DICDI
Sequence: MVGINKPEPFGTGINVPYKLQKVQYFRENFQAFFKFTPKIVLNLVVLVGVVPLTWMFLGQVQQDQKVIVNRKAREQ
What are the official names of this protein?
Uncharacterized transmembrane protein DDB_G0286421.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RIR2_HHV1K
Sequence: MDSAAPALSPALTAHTGHSATADLAIQIPKCPDPERYFYTSQCPDINHLRSLSILNRWLETELVFVGDEEDVSKLSEGELSFYRFLFAFLSAADDLVTENLGGLSGLFEQKDILHYYVEQECIEVAHSRVYNIIQLVLFHNNDQARREYVAGTINHPAIRAKVDWLEARVRECASVPEKFILMILIEGIFFAASFAAIAYLRTNNLLRVTCQSNDLISRDEAVHTTASCYIYNNYLGGHAKPPPDRVYGLFRQAVEIEIGFIRSQAPTDSHILSPAALAAIENYVRFSADRLLGLIHMKPLFSAPPPDASFPLSLMSTDKHTNFFECRSTSYAGAVVNDL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: Y2556_DICDI
Sequence: MNRVSVLSKYQCLKINSPNRFFSKYFTTSTINSTKITNDQSQTNSAGKEISQPILKSQDKLKKSILKTSTDTNFLKDINKKHRQHYIKPQKDDENIILKTLNDLKTNNLNTKELISDRLSELFLNKEMIKLISENEIESINEIFKIVLGAKKSQQPPTVAFFTKSFLNKSSKEFKMKLDSLPIIVYFLSVFESKDIMKSSDSDSDSTATNNYLTVGKGISKKFIQNFQDSISSELDITDLQEHLSDMIKLSKFSRLLGYLTNVEISRDKIKKLKDKNEIFNQLINEFGENINEIEFQNLFKNEIHFISFLLTLSRNQIITILSISNNSCYEEEEEVEEVEEVNVKGEGGELFKRVDKYEDNNKGIFNQNKIKSLIENIPVSKVRERLYWFLLMAKLRYPISENYFNDIEISLHYEKDPSFILFFFNHFKIFGYIPSDSSEAKIFQRYVRVATLDEALHYFDSIKKKPQSLNIIMITHLLLAMNKFNNQLDRKIIIDSTTNTTTNTTINTTINNNKIKKYQRSIENEMLTLYSSKIKDIIGSNSSLYNFTLSQLLHGEKWRKVLFNTLVTQLIEKHINSVTDETLLIINEYFSIHKDDVILKKLYELSKKIHLSKELLSNLTIQFLIHKRDYSNAINSLIELYKQETPILKSTLKLLIKSDPTHPILFEFYKTLPQQFELIEPTNQEQEQDQQDQPPPPQQQQEQQQEQQQQQEQQQQQDQQQQDQQQDQQEKQQIKEIKPKLKEKLESEKLINSELFLECINDPMKLYRILDGKIEILASTFQSIVMKSLESGKYQFVESIISKRFGDSSKSIDKHLLSKLITIPNLPISKDDPYNIEKLLLTNNRSENLALYNKLFNLSLNNGLLNCAKNYILKIIQQSNQRLVTSLCYQGEEALIYSYILSLNNLNIINNNQENNNNNNNDLKETIENQIIKWIESVFGCNSLNEINNDDFVFSILLGFHHSTSAYYKKQIGNLNEQQQLPSSLYLKIRSNLMQVINKYFDLIVLDRMILSSYGLESKYYGEAIDFQKDFISMITINELYQYTILKLNLLEKKNNNNNNNNNNNSYYRISIDKKFIENNDQSFNEIDLLLKNISTKQISVIVPFLMGFIENPSLMKYLSVILSNDLNKYDTATTTTTTTTIGNNFIQRLMESSSNSKEIDFLNISNTFFFKYFISVGDLKSAFKVHFKQIHILIRFRLIQDILKNQPLVMDHIFKIISSELELEQQQQQQQQQQQQQQQQQQQQQQQQQQKSSSPSLDYGLIESLLSVTSILNDSKSIHFSLKLYNLASEHAKLNNSRIPLSITNSKDLVLSGFKNRNDHFQLSENLKISDIEKQMKQTRGAGADGADEIIIKNHLTSSQLLNDIKYILIHSNYKQLKGIGFGVLRGDIPFTINDKIKVFLLVEAFAAEEGREKVNSFLNTPSLLNNSLDFELLRTPKITKLISFIFRTNSSIKHDSNYFPEFSPDFLPNKFKFYSAHLEDINNNDNDNSIQDISNIVNCNSGPESFYYRKVLKYFFKKRILKNL
What are the official names of this protein?
Putative uncharacterized protein DDB_G0292556.
Protein: OPSD_PROOR
Sequence: IHLHWYEYPPMNPMMYPLLLIFMLFTGILCLAGNFVTIWVFMNTKSLRTPANLLVVNLAMSDFLMMFTMFPPMMVTCYYHTWTLGPTFCQVYAFLGNLCGCASIWTMVFITFDRYNVIVKGVAGEPLSTKKASLWILTIWVLSTTWCMAPFFGWNHYVPEGNLTGCGTDYLSEDILSRSYLYVYSTWVYFLPLAITIYCYVFIIKAVAAHEKGMRDQAKKMGIKSLRNEEAQKTSAECRLAKIAMTTVALWFIAWTPYLLINWVGMFARSYLSPVYTIWGYVFAKANAVYNPIVYAIS
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Can use both retinal and 3-dehydroretinal as visual pigment.  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Signaling via GNAQ probably mediates the activation of phospholipase C.
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Detected on the rhabdomere membrane in the photoreceptor outer segment.
Protein: SODE_DIRIM
Sequence: MMGSFIFLLSIIISINYINSLHTVHRSNIHRNMHNGGMPKKAVAVLKSDTVNGIIYFQQNNRASATTIYGTINGLTPGLHGFHIHQYGIKANGCTSAAAHYNPFEKTHGRPTNNIKHIGDLRNIKAGADGVANVNIISNHIQLSGPLSVIGRSLVVHANPDDLGKGNGDAREESLKTGNAGSRIVCSIIGIAPST
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.  May act in the parasite defense by neutralizing superoxide generated by activated leukocytes, thus acting as both an antioxidant and an anti-inflammatory factor.
What are the official names of this protein?
Extracellular superoxide dismutase [Cu-Zn], EC-SOD.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: PYRD_YEAST
Sequence: MTASLTTKFLNNTYENPFMNASGVHCMTTQELDELANSKAGAFITKSATTLEREGNPEPRYISVPLGSINSMGLPNEGIDYYLSYVLNRQKNYPDAPAIFFSVAGMSIDENLNLLRKIQDSEFNGITELNLSCPNVPGKPQVAYDFDLTKETLEKVFAFFKKPLGVKLPPYFDFAHFDIMAKILNEFPLAYVNSINSIGNGLFIDVEKESVVVKPKNGFGGIGGEYVKPTALANVRAFYTRLRPEIKVIGTGGIKSGKDAFEHLLCGASMLQIGTELQKEGVKIFERIEKELKDIMEAKGYTSIDQFRGKLNSI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.  Molecular oxygen can replace fumarate in vitro.  Does not use oxaloacetate or NAD or NADP as electron acceptors.
What are the official names of this protein?
Dihydroorotate dehydrogenase (fumarate), DHOD, DHODase, DHOdehase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
Protein: URE2_PAEAT
Sequence: MIPGEYRLQPGSIACNSGRDAMVVEVVNRGDRPVQIGSHYHFAEANRALEFDREAAYGRRLDIPAGTAARFEPGDRKTVQLIELAGTREVHGLSNAVNGKLDGGTAVAGEPRPGIAAERDHQ
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR463_MIMIV
Sequence: MNQSINFPNNLQNNSNINNALKYLTKIIPNNKYPQQNQSHNNTTPVVTNAINPIEKLNVEEITYLQKYLENIKNKKLNLNKQSNNQTNNQTNNQTNNQTNNQTNNIRPQINNNKQPISKIQTNRTNEIYDPLKREMPIDWRILPANSLNNFRNNAFDANVFEPGSRGATSTRIGKKAQFNNPYDYGSKQNSFENVFQKPCNDPYVYDNNMLNQLNINEVPNNLRPNDLRNVDVESSLLQRESVHLPGQRNISEREFNRWNMLPFDPQDHRHIVWEDNMPRGGYATRAERLDDN
What are the official names of this protein?
Uncharacterized protein R463.
What are the subcellular locations of this protein?
Virion.
Protein: AMPA_RICPR
Sequence: MLNINFVNEESSTNQGLIVFIDEQLKLNNNLIALDQQHYELISKTIQNKLQFSGNYGQITVVPSVIKSCAVKYLIIVGLGNVEKLTEAKIEELGGKILQHATCAKIATIGLKIINRINRFTSPTFTSLIASGAFLASYRFHKYKTTLKEVEKFAVESIEILTDNNSEAMKLFEVKKLIAEAVFFTRDISNEPSNIKTPQVYAERIVEILEPLGVNIDVIGEHDIKNLGMGALLGVGQGSQNESKLVVMEYKGGSRDDSTLALVGKGVIFDTGGISLKPSSNMHLMRYDMAGSAAVVGTIIALASQKVPVNVVGVVGLVENMQSGNAQRPGDVVVTMSGQTAEVLNTDAEGRLVLADTVWYVQEKFNPKCVIDVATLTGAITVALGSTYAGCFSNNDELADKLIKAGEAVNEKLWRMPLHDDYDAMINSDIADIANIGNVPGAAGSCTAAHFIKRFIKDGVDWAHLDIAGVANSNNASALCPKGAVGYGVRLLEKFIKEYN
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_CERSK
Sequence: MAKRDYYEVLGVSRTASADELKKAYRTKAKELHPDRNADNPQAEAQFKEVNEAYDVLRDADKKAAYDRYGHAAFEGGMGGGARAGGYGQQGDFASAFSDVFEDLFGDFMGGRGGAPRSRAQRGSDLRYNLRVTLDEAYRGVQKTINVPASVACDACKGTGAEGGAEAVTCPTCSGMGKVRAQQGFFTVERTCPTCNGMGQIVKNPCKVCHGAGRVEKERSLSVNIPAGVETGTRIRLAGEGEAGMRGGPSGDLYIFIEVREHALFQRDGVHLFCRVPVSIAAAALGGEVEVPTIDGGSSRVKIPAGSQTGKQMRLRGKGMPALRGGGAGDMLIELAVETPVNLTARQKELLREFEKLSEDNNPEGKSFFSKVKGFWDGMTG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_CUPMC
Sequence: MLNALYPLLRPALFSMDAEDAHHFTLNNLMRAKRMGLAGCIGNSIADDPRTVMGVRFPNPVGLAAGLDKDGAYIDGLAAFGFGFIEVGTVTPRAQPGNPRPRMFRLPQADALINRMGFNNGGVDAFIRNVQASRWKAEGGVLGLNIGKNADTPIERAADDYLYCLERVYPHASYVTVNISSPNTKNLRQLQGASELDSLLSTLKAAQQRLADQHKRYVPVALKIAPDLDDDQVRNIGDALVRHKIDGVIATNTTISRDAVKGLPHAEEAGGLSGRPVFEASTRVVRALREVIGDALPIIGVGGIFSGADARAKIDAGAQLVQVYSGLIYRGPTLVRECASALRR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YGAY_ECO57
Sequence: MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLSASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMMILGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANLGGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISNKILRTRALLGCLTFANFSILWTSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSWLAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDARNRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEAAN
What are the official names of this protein?
Uncharacterized transporter YgaY.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFA_ERYLH
Sequence: MTDLTNQKDAALAAIAAATSLDALEEQRVAALGKKGWVSLALKTLGGMDPEERQKAAPAIQAVRAEVADAIAARKDALEREALEAQLATETLDLTLPAPQQRFGSVHPVSQVMDELAEIFADLGFAVATGPEIEDDWHNFTALNMAETHPARAMHDTFYFPDVDSEGRRMLLRTHTSPVQIRAMKAQGAPIRIIAPGRVYRSDSDATHTPMFHQVEGLVIDRDIHLGHLKWTLETFLKAFFEREDIVLRLRPSYFPFTEPSVEVDVGYSREGGRRVVGGDGNAEGHDWMELLGSGMVNRRVIEMAGLDPDEWQGFAWGLGVDRLAMLKYGMDDLRAFFDGDQRWLDHYGFSPFDQPTLSAGVGARS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTSA_MYCBO
Sequence: MAPSGGQEAQICDSETFGDSDFVVVANRLPVDLERLPDGSTTWKRSPGGLVTALEPVLRRRRGAWVGWPGVNDDGAEPDLHVLDGPIIQDELELHPVRLSTTDIAQYYEGFSNATLWPLYHDVIVKPLYHREWWDRYVDVNQRFAEAASRAAAHGATVWVQDYQLQLVPKMLRMLRPDLTIGFFLHIPFPPVELFMQMPWRTEIIQGLLGADLVGFHLPGGAQNFLILSRRLVGTDTSRGTVGVRSRFGAAVLGSRTIRVGAFPISVDSGALDHAARDRNIRRRAREIRTELGNPRKILLGVDRLDYTKGIDVRLKAFSELLAEGRVKRDDTVLVQLATPSRERVESYQTLRNDIERQVGHINGEYGEVGHPVVHYLHRPAPRDELIAFFVASDVMLVTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELRHAYLVNPHDLEGVKDGIEEALNQTEEAGRRRMRSLRRQVLAHDVDRWAQSFLDALAGAHPRGQG
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose and in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P).  Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Probably also able to use ADP-Glc, CDP-Glc, GDP-Glc and TDP-Glc as glucosyl donors.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: MNME_PSEF5
Sequence: MNVPRETIAAIATAQGRGGVGIVRISGPLAGAAAKAISGRELKPRFAHYGPFLSEQEEVLDEGIVLYFPGPNSFTGEDVLELQGHGGPIVLDMLLQRCLELGCRLARPGEFSERAFLNDKLDLAQAEAIADLIEASSAQAARNALRSLQGAFSQRVYNLTEQLIALRIYVEAAIDFPEEEIDFLADGHVLSMLDAVRDELSTVLREAGQGALLRDGMTVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDILREHIHIDGMPLHVVDTAGLRDTEDQVEKIGVERALKAISEADRVLLVVDATAAEAADPFALWPEFLEQRPDPAKVTLIRNKADLTGEPIALETCDDGHVTISLSAMAAGSGLELLRDHLKACMGYEQTSESSFSARRRHLEALHYASAALEHGRAQLTLAGAGELLAEDLRQAQQSLGEITGAFSSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_BIFLD
Sequence: MSPVISHPRSAAARHQSDELSPITITVDCPAKTNLTLEVGPAHDEWGGRHELDTTYCAIGVYDTVTATAKQPGAGFSLELEGAYLGDLASSRSDMRRNHAVLALFAMAQAAEREPDVALTITKRIPVGAGLGGGSADAAATMLAVNRLWELNWPIERLRTIAATLGADMPFCLTGGLAYGTGFGERITDIAPGSRDELALIEQGFSGEVLVGAYQSQLSTPEVYHTFDIVGAAEGDRNHLQAAAISLHPRSGQAIDAATQAGASHAFVSGSGPSVVAFAADEAAAQRIIEVWRDTAVVDRIIRAKSPEHPNISVRQ
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.