PharMolix/UniProtQA huggingface dataset:
Protein: GLYA_CHLPB
Sequence: MNMDILQRQDKGIFDAITAEVRRQTETLELIASENFASRAVMEACGSVMTNKYAEGYPGKRYYGGCEFVDIAENLARDRAKKLFGCDYVNVQPHSGSSANMGVLFAVLKPGDRIMGLDLSHGGHLTHGSKVNFSGQLFEAHSYGVDRETGCIDMNKVEEMALEVRPKLIICGASAYSQGFDFKAFRDVADKVGAFLMADIAHPAGLIAAGLLNDPMPHCHFVTTTTHKTLRGPRGGMIMMGKDFENPLGITVKTKKGSRTKMMSEVIDAEIMPGIQGGPLMHIIAAKGVAFGEALQPEFKDYAVQVRNNAAVMAERFSGLDYQIVSGGTKNHLMLIDLRNKNVTGKVAENLLHDAGITVNKNMVPFDDKSPFVTSGIRIGTPAMTTRGMQESHAENIVGFIDRVISAADSEGIEKVCAEVRSDVKAMCKDLPLNDFGPE
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG70_BPMD2
Sequence: MPLTSLVGQFEGVVYTQPEKLVERHGWLEAWKCKAWMEDDPSQVVTLLLAYRSPLCRDTKPMYRPVAEEILKADQVDVLARGFRHDDNMMHGRGEFLVARLRPHSFVESPMCPSLDEIREVVGSTVETALTGNGEMAAP
What are the official names of this protein?
Gene 70 protein, Gp70.
Protein: MCAPS_PLRV1
Sequence: MSTVVVKGNVNGGVQQPRMRRRQSLRRRANRVQPVVMVTAPGQPRRRRRRRGGNRRSRRTGVPRGRGSSETFVFTKDNLVGNTQGSFTFGPSLSDCPAFKDGILKAYHEYKITSILLQFVSEASSTSSGSIAYELDPHCKVSSLQSYVNKFQITKGGAKTYQARMINGVEWHDSSEDQCRILWKGNGKSSDSAGSFRVTIKVALQNPKYDSGSEPSPSPQPTPTPTPQKHERFIAYVGIPMLTIQARENDDQIILGSLGSQRMKYIEDENQNYTKFSSEYYSQSSMQAVPMYYFNVPKGQWSVDISCEGYQPTSSTSDPNRGRSDGMIAYSNADSDYWNVGEADGVKISKLRNDNTYRQGHPELEINSCHFREGQLLERDATISFHVEAPTDGRFFLVGPAIQKTAKYNYTISYGDWTDRDMELGLITVVLDEHLEGTGSANRVRRPPREGHTYMASPHEPEGKPVGNKPRDETPIQTQERQPDQTPSDDVSDAGSVNSGGPTESLRLEFGVNSDSTYDATVDGTDWPRIPPPRHPPEPRVSGNSRTVTDFSSKADLLENWDAEHFDPGYSKEDVAAATIIAHGSIQDGRSMLEKREENVKNKTSSWKPPSLKAVSPAIAKLRSIRKSQPLEGGTLNKDATDGVSSIGSGSLTGGTLKRKATIEERLLQTLTTEQRLWYENFKKTNPPAATQWLFEYQPPPQVDRNIAEKPFQGRK
What is the function of this protein?
Participates, together with the proteins P0 and P1, in the inhibition of the induction of aphid-induced host phytohormones (PubMed:31758809).  This could play a role in the attraction to the infected plants by aphids (PubMed:31758809).
What are the official names of this protein?
Readthrough protein P3-RTD, P3-P5 readthrough protein, P74, Readthrough protein, RT protein.
What is the protein family that this protein belongs to?
Belongs to the luteoviruses readthrough protein family.
What are the subcellular locations of this protein?
[Minor capsid readthrough protein]: Virion. Host cell junction, host plasmodesma. Host periplasm. SUBCELLULAR LOCATION: [Cleaved product]: Virion.
Protein: H90B3_HUMAN
Sequence: MPEEVHHGEEEVETFAFQAEIAQLISLIINTFYSNEEIFLQELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLALVDTGIGMTKADLINNLRTIAKSGTKACMEALQAEKLVVITKHNDDEQYAWESSAGGSFTVHADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEQDKEISDDEAEEEKGEKEEEDKDDEEKPKIKDVGSDEEDDSKEYGEFYKSLTSDWEDHLAVKHFSVEGQLEFRALLFSPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIHGVVDSEDLPLNISREMLQQSKILKYVSHMKETQKSTYYITGESKEQVANSAFVERVRKQGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKEKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMEQIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNHIYHMIKLGLGTDEDEVAAEEPSDAVPDEIPPLEGDEDASRMEEVD
What is the function of this protein?
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins.
What are the official names of this protein?
Putative heat shock protein HSP 90-beta-3, Heat shock protein 90-beta c, Heat shock protein 90Bc.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC7_DICDI
Sequence: MNWDSNNNNNKNSNNNNNNSSSSSYNINNNYSSFNNSNNNNINNNNINTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNSSNNYHLAHINVYQQYPIKPLPISFNSFNTNMFQQQQQQQQQQQQLPQHLPPLGSSGSSNGGPNLMGYAQIPPNYFKPLSPPSFHPPTSPQSFFNNNTNNNNNNNNNNNNNINININNNNNSNNYINDSTNSNNLNTSNGAINTSSHLFINSPNHHSDNRSFIESRSPASMNASPIHFNDPTFKVPVHLPSLSITNSPSLNSSIDSSYRLNNNNNNNNNNGSNNSSFNSTPTKFEQLQLQLQQQQLQQQLQQQQQLQQQQQQLQQQQQLQQQQQQQLQQQQQQQLQQQQQQQQQQLQQQQQLQQQQQQQSTSHIHFSTAPTPIVSHHYNLQQPLQQYPQNIYSHTNILNQNNNSKPINTNSSSSNNNNNNNNNNNNNNNNNNNNNNCNYNNSNNSYNNNTTNTNNNPNNKRSQTKNQQQQQPQPQQQQLQQQQPQQSVINVNKKTTKVSKTKTSNQKLTVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTIQQQQQQQSNDIKLLLKNSIYSSRNDLKELLSQPTEYTDSEYPEIVGKYRILEKIGQGTFSGVYKSVCIDGPNIGLIVALKRVAPTSSPARILNEIHSLLRVGGHYNVSALFGALRYKDQVTLILPFFEHDSFKDYFFQMSNENIKHYLYALFDSLRHIHQNNICHRDVKPTNFLYSIKNNSFLLIDFGLAQEMPNSNSNSNSNSNSNSNSNSNSNSNSNSNNNNNNNNNNTNNNFNGNNSNNDFNNFINMNNSNSNNNNNNNSNNNNNNNNNNNNNNNNNSNNNNNSNNSQEEIILPSTNENGTTTSNASSTSNTTSSSSSSSNKSKNLRNDPKPQPAPRAGTRGFRAPEVLLKYNKQTTAIDIWSVGVILLCMISGRYPFFISPDDMTSLAEIVSIIGTKKIVDIAHLLEKKISISHSIPPTPWRDLSRRLRSESSCDKQDVPVELYDLLERCLDPNPLTRITASEALLHPFLVVNNNSNNNNNNS
What are the official names of this protein?
Probable serine/threonine-protein kinase cdc7, Cell division control protein 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.
Protein: HTPX_SALHS
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLLIMALLFGFGGSFISLLMSKWMALKSVGGEVIEQPRNERERWLMNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRIIAQIAAGFLGGNRDEGEGSNGNPLIYFAVATVLELVFGILASIITMWFSRYREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTHPPLDKRIEALRSGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BRK2_PELRI
Sequence: RPPGFTPFRIA
What is the function of this protein?
Inhibits ACE with a Ki of 1. 6 uM, and targets B2 bradykinin receptor (BDKRB2).  Provokes contraction of smooth muscle preparation (ileum).  In vivo, induces an early hyperalgesic effects in living rats after intraplantar injection (By similarity).
What are the official names of this protein?
[Thr6]-bradykinin RA-11.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: EF1B_SCHPO
Sequence: MGFSDLTSDAGLKQLNDFLLDKSFIEGYEPSQADAVVFKAVGVAPDTAKYPNGARWYKQIATYDLATLPGTAKEVSAYGPEGAAAAEEDEIDLFGSDEEEDPEAERIKAERVAEYNKKKAAKPKAVHKSLVTLDVKPWDDETPMDELEKAVRSIQMDGLVWGLSKLVPVGFGVNKFQINLVVEDDKVSLEALQEELEGFEDYVQSTDIAAMSKL
What is the function of this protein?
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: DDL_STRTD
Sequence: MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYNAFEVKTYFITQSGDFIKTQEFIETPGDDEKLMTNDTVEASQAIKPSDIYEEDAVVFPVLHGPMGEDGSIQGFLETLKLPYVGTNVLSSSVAMDKIMTKRILEVAGVPQVAYTGYIEGEDLEAAVAETLEKLTFPVFVKPANMGSSVGISKAENESELRSAIDLALKYDSRILIEQGVVAREIEVGILGNTTVKTTDPGEVVKDVAFYDYQAKYIDNKITMDIPARVPVEVMTQMRAYAAKAFRALGGCGLARCDFFLTEDGAIYLNELNTMPGFTQWSMYPLLWENMGLSYSDLIKELVVLGQEMFDKRESHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_AERSA
Sequence: MAAKEVKFGNEARIKMLEGVNILADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFQNMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVIAAVAELQVLSQPCADNNAIAQVGTISANSDEKVGRLIAEAMDKVGRDGVITVEDGQGLDDELAVVEGMQFDRGYLSPYFVNKPETGAVELDDPFILLVDKKVSNIREMLPVLEGVAKAGKPLLIVAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIAMLTSGGTVIEEVGMELEKATLEDLGRAKRIVITKENTTIIDGVGDAALIESRVAQIRQQIEETSSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVDDALHATRAAVEEGVVAGGGVALVRVAAKLAGLRGDNEDQNVGIKVALRAMEAPLRQIVINAGEEASVIANAVKNGEGNFGYNAYTEQYGDMLAMGILDPTKVTRSALQFASSIAGLMITTECMITELPKKDTPAMPDMGGMGGMGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMTR2_DANRE
Sequence: MNRGRGVRKRNAPEKASILETCDEEIRAEVAQLFNKVRSYVPPAGEKWTLPDPNVVLCDPHVSHPRLQALKHSLNEVKNQLSDKDLSVWHQHTCFTNRAGTVTSHLRSTTNAELCTQAWAKFYEILGTFQLLPDSALKTGELNSIHLCEAPGAFISALNHFLKTSSLHCDWNWIANTLNPYYEANGRGCTITDDRLIVHTLPWWFFGSDNTGDIMLQKHLLELPRFVSNMRSVDLVTADGSFDCQGDPGEQERLVAPLQHCEAICALLLLGTGGSFVLKMFTLFEHSSVCLLYLLACCFRSVNIFKPGTSKSGNSELYIVCLDYQAKEQIRPLLSKLIRNYGPDLASTASLFPRRCIPDSFLSQHEEICTFFQALQVNTIQENLRLFVCMSTEQRRRLEQLREYAAEFYTKRFSVQYLPRKSWVCRGGVVRWVKVCERKQMGSLNQRKEMELQGWKQRLAQGNYGPFIEKHLVAAEGCEVVLNGPLDECDLGAWFALEGAALPKVCSSIFCDQEMLDFLNEALEGNLRVKTVNWSLKALPTCSSCSSDSPVSILSEICSHPDVTSCLVLGSQSWCDDKLTGVRIQPEFLQGPSYCGVQNVTMHDGQPDYQLELLNAVLFALQKQDQGSTLVIPLSSALTRFTSGLVFTLHLCFRYITFRCLSGWPPAALVCMGFSPPSALPSLLDFLQNVMEKMKKVELGRQVLQFVPLEELLRGELPHFLSSFNTAVIRQQLHMLIQLDQST
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs.  Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2).
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2, Cap methyltransferase 2, Cap2 2'O-ribose methyltransferase 2, MTr2, FtsJ methyltransferase domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ATPF1_METS4
Sequence: MLEPEFWVAVAFVIFCGIVWKAGGFDQIINGLDRRGERVRRELEEARRLREEAAALLADYQKRRGEAEREAEAIVANARAEAERAAAEGHARLNDFVARRTKAAEAKIAQAEAQAAAEVRAAAAEAAVRVSETILREKVTGDAAQDLIRRSLGDIRTRLRA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS15_SYNAS
Sequence: MLSSDQRGSIIENYQLHEKDTGSPEVQIALLSARIEYLTDHFKVHKKDHHSRRGLLKLVGQRRRLLDYLKNKNIERYRQVIQRLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CSCL2_MOUSE
Sequence: MLPFLLATLGTAALNSSNPKDYCYSARIRSTVLQGLPFGGVPTVLALDFMCFLALLFLFSILRKVAWDYGRLALVTDADRLRRQERERVEQEYVASAMHGDSHDRYERLTSVSSSVDFDQRDNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAESEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPAMINPKPCGHLCCCVVRGCEQVEAIEYYTKLEQRLKEDYRREKEKVNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRASSCSEALHISNWTVTYAPDPQNIYWEHLSIRGFIWWLRCLVINVVLFILLFFLTTPAIIITTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDAVSSRSNGRPPTAGAVPKSAKYIAQVLQDSEGDGDGDGAPGSSGDEPPSSSSQDEELLMPPDGLTDTDFQSCEDSLIENEIHQ
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel (PubMed:27045885, PubMed:31243992).  Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion (PubMed:30382938).
What are the official names of this protein?
CSC1-like protein 2, Transmembrane protein 63B.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL13_XANOR
Sequence: MTTFTAKSETVQRDWYLVDAAGKTLGRLSTELARRLRGKHKPVYTPHVDTGDYLVVINAEKIVVTGNKLKDKKYHRFTGYIGNLKTESLEQALQRHPERVIEIAVKGMLPKGPMGRTMYRKLKVYSGAEHPHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL2_BACCR
Sequence: MGIKKYNPTTNGRRNMTTNDFAEITTDRPEKSLLAPLSKKAGRNNQGKITVRHQGGGHKRQYRIIDFKRNKDGIPGRVATIEYDPNRSANIALINYVDGEKRYILAPKSLEVGMEVMSGPEADIKIGNALPLINIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGKEGKYVLVRLTSGEVRLVLSACRASIGQVGNEQHELIKIGKAGRSRWLGKRPTVRGSVMNPVDHPHGGGEGRSPIGRKSPMSPWGKPTLGFKTRKKNKASDKFIVRRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GP_INSV
Sequence: MALKETDAKIHVERGDHPEIYDEAYYDRSVDHKNEILDTLAEMLQNATGKTLRPTRDTQTVLANNEVPQSSSGLSSTPTTISIMDLPNPCLNASSLTCSIKGVSTFNVYYQVESNGVIYSCISDTITKLGNCEGSSELPRSFETVPVVPITKIDNKRKLSIGTKFYIIESLENYNYPIMYNSRPTNGTVSLQSVKFSGDCKISKTNIVNSYTVSLTTPEKIMGYVVKREGSDMSHSIISFSGSVSLTFTEENMDGKHNLLCGDKSSKVPLVDKRVRDCIIKYSKNIYKQTACINFSWFRLIMIALIVYFPIRYLVNKTSKTLFYGYDLLGLITYPILLLINYLWSYFPLKCKVCGNLCLVTHECSKLCICNKNKASEEHSEECPIITRTAEKNKKYNWASIEWFHLIVNTKIGLSFLKAVTETLIGFLILSQMPMSMAQTAQCLDSCYYVPGCDRFVTNRYDKCPEKDQCFCAIKENSIVESNFLTNVVTEGPMDCIPYQECKGRITENALVTFVKCRFGCEYASIFQSKPLDNGFLEYSGDTLGLNAVNLHFMKRLRNGIIDFYNKTEKYGYISGDALKSNESDIPESIFPRKSLIFDSVIDGKYRYMIEESLLSGGGTVFSLNDKSSSTAQKFVVYIKKVRIQYDVSEQYTTAPIQSTHTDFFSTCTGKCSDCRKEQPITGYQDFCITPTSYWGCEEVWCLAINEGATCGFCRNVYDMDQSFRIYSVIKSTIKSEVCISGFVGAKCFTVSEEVPSESGYFQADILADFHNDGLTIGQLIAHGPDSHVYAGNIARLNNPSKMFGHPQLSHQGDPIFSKKTLDTNDLSWDCSAIGKKTITIKSCGYDTYRFKTGLNQISDIPVQFTDQNSFYMEKIFSLGKLKIVLDLPSELFKTVPKKPILSSVSLSCKGCFLCSQGLRCAASFISDITFSARLTMKQCSLSTYQIAVKKGANKYNLTMFCTSNPEKQKMIIEPEGDKSYSVEALVDSVAVLEPENIIDQNDQHAHEEQQYNSDTSVWSFWDYVKSPFNFIASHFGSFFDTVRVVLLILFVFALAYLCSIVATMCRGYVRNKSYKTKYIEDTNDYSLVSTSSGKDTITRRRPPLDFSGI
What is the function of this protein?
Forms the spikes present at the surface of the virion together with Glycoprotein N.  They are able to attach the virion to a cell receptor and to promote fusion of membranes after endocytosis of the virion (By similarity).  Probable class II fusion protein (Probable).
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the tospovirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein N]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Glycoprotein C alone is retained in the membrane of the endoplasmic reticulum, but not transported to the Golgi. Coexpression of Glycoprotein C and Glycoprotein N results in efficient transport of Glycoprotein C to the Golgi complex, indicating that their interaction is essential for proper targeting to this organelle, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=Glycoprotein G2 is retained in the Golgi complex and probably contains a Golgi retention signal.
Protein: RTSTL_DANRE
Sequence: MWWILLFLEWFVDWARGTFWYLFGRRSGLCKGTISPQGPLVVDQEKKDKVLQKEYASNEVPDNLDVIVIGSGIGGLTAAAVLARLGKKVLVLEQDKQAGGLCKTFTEKGFEFDCGFYYVGQLHENSFLKIALDLITDGQVHFAEQGSHVETVVIGKGPECKEYTIYNGKKQMEAHLKKQFPNDAKAVEEFFKIMKICSEKVRLLCMLKMVPLWFARFILRTGIADFISPILKYSRTSTSEVVKSLTSNQDLLTVFSKTFCGVPPKNSSCMIDALLLHHSKRGVYYPQGGASEIPYHIIQVLEKHGGKVLVNAPVSRVLVNEQQNAYGVAVKTGDEDIEIKASVVVSNAGVFTTFQKLLTPEIQADPQVQEYLKALKPGKGFFQVFAGFNATMEELGISSTDMRLYKGNNVDEMMEEYFASDKQDAPDNVPMMYLSFPSAKDPTSSTRFPGQSRMVIHTLVNPKWFEQWENVNEAERGEEYENYKMRFANHLFDWACVRFPQLKEKVALLHAVTPINMHGLGASYCSMSAEHNLERYQPLNIATIRCNTPVKNLYLSGQDIFTAGYSGALHGGFLCASTVMDRCLHIDLLLQQKKLKSKSVKKLE
What are the official names of this protein?
Inactive all-trans-retinol 13,14-reductase, Inactive all-trans-13,14-dihydroretinol saturase B, RetSat B, Retinol saturase (all-trans-retinol 13,14-reductase)-like protein.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily.
Protein: VSPA_SOYBN
Sequence: MKMKVLVFFVATILVAWQCHAYDMFPLRMNTGYGARTPEVKCASWRLAVEAHNIFGFETIPEECVEATKEYIHGEQYRSDSKTVNQQAYFYARDLEVHPKDTFVFSIDGTVLSNIPYYKKHGYGVEKFNSTLYDEWVNKGNAPALPETLKNYNKLVSLGFKIIFLSGRTLDKQAVTEANLKKAGYHTWEKLILKDPQDPSTPNAVSYKTAAREKLIRQGYNIVGIIGDQWSDLLGGHRGESRTFKLPNPLYYIQ
What is the function of this protein?
May function as somatic storage protein during early seedling development.
What are the official names of this protein?
Stem 28 kDa glycoprotein, Vegetative storage protein A.
What is the protein family that this protein belongs to?
Belongs to the APS1/VSP family.
Protein: RRAA_SODGM
Sequence: MKYDTSELCDIYQEDVNVVEPLFTNFGGRTSFGGQITTVKCFEDNGLLYDLLQENGHGRVLLVDGGGSVRRALIDAELGNLAVQNEWEGIVVYGAVRQVDDLEELDLGIQAMAATPAGAASEGIGESDTRVNFGGVTFFSGDHLYADNTGVILSKDALDLE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICLN_RABIT
Sequence: MSFLKSFPPPGPTEGLRHQQPDTEAVLNGKGLGTGTLYIAESRLSWLDGSGLGFSLEYPTISLHAVSRDPNAYPQEHLYVMVNAKFGEESKELVADEEEDSDDDVEPISEFRFVPGDKSALEAMFTAMCECQALHPDPEDEDSDDYDGEEYDVEAHEQGQGDIPTFYTYEEGLSHLTAEGQATLERLEGMLSQSVSSQYNMAGVRTEDSIRDYEDGMEVDTTPTVAGQFEDADVDH
What is the function of this protein?
Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins (By similarity).  Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (By similarity).  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core) (By similarity).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP (By similarity).  Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus (By similarity).
What are the official names of this protein?
Methylosome subunit pICln, Chloride channel, nucleotide sensitive 1A, Chloride conductance regulatory protein ICln, I(Cln).
What is the protein family that this protein belongs to?
Belongs to the pICln (TC 1.A.47) family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cytoplasm, cytoskeleton. Note=A small fraction is also associated with the cytoskeleton.
Protein: AXE1_ASPFI
Sequence: MLSTHLLFLATTLLTSLFHPIAAHVAKRSGSLQQITDFGDNPTGVGMYIYVPNNLASNPGIVVAIHYCTGTGPGYYSNSPYATLSEQYGFIVIYPSSPYSGGCWDVSSQATLTHNGGGNSNSIANMVTWTISEYGADSKKVYVTGSSSGAMMTNVMAATYPELFAAGTVYSGVSAGCFYSDTNQVDGWNSTCAQGDVITTPEHWASIAEAMYPGYSGSRPKMQIYHGSVDTTLYPQNYYETCKQWAGVFGYDYSAPESTEANTPQTNYETTIWGDNLQGIFATGVGHTVPIHGDKDMEWFGFA
What is the function of this protein?
Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone.
What are the official names of this protein?
Acetylxylan esterase A.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 1 (CE1) family. AxeA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTS_LEGPH
Sequence: MASSHTPMMQQYLRIKTDYPDMLLFYRMGDFYELFFDDAKRASQLLDLTLTHRGQSADKPIPMAGVPYHAVENYLARLLKKGESVAICEQIGDPATSKGPVERQVTRIITPGTVTDEALLDARKDNILLAIHTQKQKIGIAWVDLGGGRFHLQELTEEHQLNAELVRLQPAELLCKESTPLPSFCSNFAVKFRPGWEFDASNAHKLLCEQFSVTDLSAFGEQNYPTALIAAGALLAYLKTTQKQSLPHLTTLTLEQSEDYLQLDASTQKHLELFENIHGGGEHCLLSILDKTACAMGSRLLKRWLGKPLKQHAIIQTRQQAIKEIIFLQQDVSLHQLIKQCADVERIVSRIALKSARPRDLVSLLQTLTLLPAIHDELQENKSLLINEIKKEISPLPLLQQLLETAIIDNPPMLIRDGGVIAPGFDEELDELRNLSSNAHETLVKLEQEEKNRTGLSTLKLGYNSVQGFYIELSKAQAQNAPPHFHRKQTLKNVERYITPELKLFEDKVLSAQSKALAREKWLYDNLLEEIQQYIPELSDLAKSLAQLDVLVTLAERAQSLNWNCPNLVPESGIMIQAGRHPVIEPLLQERFIANDLELKPNQNMLLITGPNMGGKSTYMRQTALIVLLAHIGSFVPADKVTLGPLDRIFTRIGASDDLSSGRSTFMVEMTETAQILRQATSQSLVLIDEIGRGTSTYDGMALAYASCAFLASTIKAYTLFSTHYLELTELPKEFSCIRNVHLQASIKTGQIVFLYRVEEGCANRSYGLEVAELAGIPKEVLKLAHEHLNQIQDTQSILVQTQIIKPPTSPVLTELKKIDPDRLTAKEALDLIYKLKHLECAESIN
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: GRCA_SALTI
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKSGFAEDEVVAVSKLGEIEYREIPMEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: GPH_NEIG1
Sequence: MNAAIEHVQAVAFDLDGTLCDSVPDLAAAAEAMLEQLGMKPLPAKVVESYVGDGIGKLVHRVLTNDRDREADSELWEKGFVSYMKYYRDHLSVFTRPYPETEAGLALLKSLGIPLVIITNKNEILAAELLKQLGLADYFSLILGGDSLPEKKPSPLPLRHAAEVLGIDAANMLMVGDSRNDIIAAKAAGCLSVGVTFGYGDMTLLSQDDTTRPDRIIGALPEIYENLQPQKNKDEE
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.