PharMolix/UniProtQA huggingface dataset:
Protein: KTU_AEDAE
Sequence: MSNVGDKFELSRDEFRNITQCLGNEEFRKLFAEYCQELKDPENRKQYEEELKLMEAERGYDVKFIKPLPGYVIKTVVDGKTKAFVNVCHCDLVGKPSSQCSTNKRGEKGLKWSIPYAQSQPRKDYDNKNVDCVVYDVVFHYDTLHLTKSNKNFRKLVTDTALDAVEGAFHVSLDRVNLKFPKLQYKGVAKMTVIRQKLKNFETRRKDGLIDTLYRASEQSKITHDNSADKENVNKQTFKSASQLEYTTPAYKLIHRKEVEYHELTGELDAKLDAAIPKELVLVIELPLLKSANQCTLNVTSSEVHLISDSPAKYKLEVKLPYTVLEKNGSAKFNTDETTLTVLLPVARNRRTLNDVTVSSNDQSMPDEMDQKPVERVKPLKEPQLVHSNANKKIIFPKFSANKMDNIFAFTLNVRNVDPSSIELQKGTDTVSCRFTNIGNGFFPCYYIFFLRFPNANITEVQHEEWDNNIILQVVLDHGLIDCYYAGTNENDLVQYSIMEDITDKINKFGKEIEDDSLCIAVSKNAIKQERKSSHLSIEIKTKDEIESDEGIDSALEGELKTDQSMQEDENPDEINTRTVEDDTKVAKENVKKVDQETAHEGKKSKKNQRRKNKKRSLSESCCDHLKVTINNDNPKPESGNEANSFEGTGSSSEATSKQRKARSVSESCPARDNNGVESDSVDNLSALIQFNHKYKGILKRSSLQRSISECSSIDEHYYLGTSVDGSSVAESVDHTNGELSESCRKTVRFNDAIKTKLFRSNTSILGQKKKNAKKNESKRRALTRRLSEGESTDNEDKDHQTTNEAPGSVVQRDTEHDSGISLDSDAAHPIEINADTEVQNQHQNDSTKPIEINRKVEKKFIASKNNNCNVKAQFIKSKRNDSSDIEFKSDMIFDIEM
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal homolog.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_PROM5
Sequence: MLTVAILAAGKGTRMASSLPKVLHKLSGKTLLQRVIDSCNELKPDKIFIIVGHKSKEVKDSVFKNNNIHFIVQKPQKGTGHAVQVLSQKVKKHDGKLIVLNGDVPLIKGETLKKLIHYHDSQKADVSLITTKKKNPHGYGRVFAKDNLIEMIIEEKDCNNVQKSNLLINAGIYCFNWKSLSKIINTIKSNNKQNEIYLTDAIYLLKKSYSFEILDNGELQGINNRVQLSKCEETIQNLIKEKHMLGGVTFINPASCTVSEESIIGKDVIIDANTHIRGNSKISNNCKIGPNTFIKDTIINENCEIINSTIFNSVLMDFVNIGPYSHIRPNCEISSYSRIGNFVEIKNSQLDKEVKVNHLSYIGDSTVGKHTNIGAGTITANFDGKKKHPTFIGENSSIGANTVLIAPINLGDSVTTGAGSVITKDSQNNSLAIARTKQVNIENWKKN
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFB4_KLULA
Sequence: MDAIADTVFQGTKSKTQEIEDTPSLLTVVVDTSIHSWVQLTKQQSGSGSEGSSGEKQLIEALKSIVVFLNAHLAFNSGNQVCLIAAHSEGMKYLYPSADSKPSMSMVSSDMYRGFRNVDEIVVEQWYRLFKEELEGQESKVSMKSSLSGAMSSALTYVNRILKENENTSLRSRLLVITCGTSQGKDEIFQYIPIMNCIFSATKMKCSIDVVKIGGGIESTFLQQATDATSGVYLHVENTRGLIQYLSTAMFIDPSLRNVIIKPNQGSVDFRTSCFLTGKVVAVGFVCSVCLCVLSVIPPGQKCPACDSPFDSKIIARLRRKPVLSNGVPKKKNVSNK
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH subunit TFB4, TFIIH subunit TFB4, RNA polymerase II transcription factor B subunit 4.
What is the protein family that this protein belongs to?
Belongs to the TFB4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_RUMCH
Sequence: MPLVEKRYAQALLELSGSDINSIKEEFGDFTNLYNSDKDFRDFLNNPVVKTDKKQALIRSVFTDRLSKNMLNMILLLVSKHRTAEIPGIFNQFIQMANETANVLDMKIIMAAPMDEVQLETLREKFKKKYNAVAVNSTEIVDESLIGGLKVIIGDKVYDGSVKGRIESLTEIVSV
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DCNL3_MOUSE
Sequence: MGQCVTKCKNPSSTLGSKNGDRDPSNKSHSRRGASHREEQVPPCGKPAGDILVNGTKKAEAATEACQLPTSSGDAGRESKTNAEESSLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKREVEGRGTLSSGQEGLCPEEQT
What is the function of this protein?
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes and may play a role in the cell cycle progression by regulating the SCF ubiquitin E3 ligase complex, after UV damage.  At the cell membrane, can promote and as well inhibit cullins neddylation.
What are the official names of this protein?
DCN1-like protein 3, DCNL3, DCUN1 domain-containing protein 3, Defective in cullin neddylation protein 1-like protein 3.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=After UVC treatment, the protein enters to the nucleus gradually. Cell membrane localization is essential for CUL3 neddylation.
Protein: Y441_HALMA
Sequence: MNYLVAMEAAWLVRDVDDIDDAIGVAVSEAGKRLNEAEMDYVEVEVGATGCPACGEPFDSAFIAADTALVGLVLEMDVFNAESPEHAQRIAKSEIGGALRDVPLKVVEVFETEADEDEAEAEA
What are the official names of this protein?
UPF0212 protein rrnAC0441.
What is the protein family that this protein belongs to?
Belongs to the UPF0212 family.
Protein: JBP1B_TRYCC
Sequence: MKQKRGKQDVKMVESAPPQLLPKKGRLEISELAPQQRTIRTAEEIEMAYNEAVRKHPFYDNADHTIDFHDATVFRDARGVVGGVLLPGALPAFAATMAADVLRPAAVRTSLRSNMFGGFAPLSGIAGYFDYRGSPVELKCRKTSFTYENVHSWPNVFPMIDYVSAIYKAVFPERWAAQDAAVPDIVRIHGSPFSTLTVNQQFRTASHTDAGDFDMGYGLLAVLEGKFEGLSLALDDFGVCFRMQPRDVLIFNTHFFHSNTEPELNHPKDDWSRLTCVCYYRAALGEPACVAEYERRLARAKEIGASPPPAVDAILQKDNGNNFNKPAPTFTYSLTPFGGAASICSLHCCTAKLLRLHELLLENPTLEVILFGESLRTDDGLPRREKEQLISVHLPVVVKMSPSGGFSELGGALKAAEEKQYFFEEKYLADELGPDLMSMWTQSRAHWLRLVKEDWERLCRRDPERTKFTWNNSSAMNAAFFDLCEVAKQMMIGLLNKETPSSAENHSFWILFAAHLNYACTTENGMPRDAVGMHKLNVKLKDFHFGGTRYLKDMPPEEQERRLERKKRIEEARRRGNAARETHTDNWLLNDTFDYQQEDRKVEFEENGWMTPEAYVKHLGLKPCGDVTAAASPTEPIHVLVVLPRPAAAAPKDVKRDVPLATSEESIRLLMNPAAQRVLTGKARNVTLPSPLSFGGVKITVLFDGDDIDCIHPDFVVLQHLLAAIEEDEAAKARVKYWAHVARYCVFVVETDVRDRRHFLLREEVRVAYEDVAEDCFRSLHAAAYSTKCNRLRTTPSLIALSNSKNIGLRFKFRGSPLNTIALIVVGERLD
What is the function of this protein?
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU).  DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation.  Also specifically binds to base J-containing DNA (J-DNA).  Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis.  Thymine dioxygenase activity and J-DNA-binding are independent functions (By similarity).
What are the official names of this protein?
Thymine dioxygenase JBP1-B, J-binding protein 1B, Thymidine hydroxylase JBP1-B.
What is the protein family that this protein belongs to?
Belongs to the TET family. JBP1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGR_SALPK
Sequence: MRSSAKQEELVRAFKALLKEEKFSSQGEIVLALQDQGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPASGFSVRDLYEAILELFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT3A_ORYSI
Sequence: MSDKCGNCDCADKSQCVKKGTSYGVVIVEAEKSHFEEVAAGEENGGCKCGTSCSCTDCKCGK
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein 3A, Class I metallothionein-like protein 3A, OsMT-I-3a, OsMT3, OsMT3a.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: HEM6_SHIF8
Sequence: MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCQPFGEDVYPRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRDJ1_HUMAN
Sequence: TDKLIFGKGTRVTVEP
What is the function of this protein?
J region of the variable domain of T cell receptor (TR) delta chain that participates in the antigen recognition (PubMed:24600447).  Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1.  Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:28920588, PubMed:23348415).  Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT.  This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089).  Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes.  The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames.  The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714).
What are the official names of this protein?
T cell receptor delta joining 1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RBFA_ACIF5
Sequence: MLHSSHRPYPRGARVAHLLREEIAAVLPRLHGMSSGLSPLPPSITMVDLPTDMRSATVYFSLMDGPDRADTIREVLQDHAGEIRQLLGRRLALRRIPPLHFVYDARFDRGAEMAELLAHLPPAPEDLP
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA2_STAA3
Sequence: MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHNNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIKQTLKAADYAFSQMK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BORGP
Sequence: MSRKNKKIKKKIFIDTRYNSRIVAKFANRMMYDGKKSISESILYSSIDLLADKLEDSDKMAVFYKALDNIKPLVEVRSRRVGGATYQVPVEVREERREALAMKWIIFAARKSSGRSMKEKLSNELLNAYNSTGAAFKKKEDTHRMAEANKAFTHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SELO_BURP0
Sequence: MSFSRSEAAPAAPLPDLAATLAAPRDDAFQQLGAAFVTRLPAAPLPAPYVVGFSDDAARMLGLEPALRDAPGFAELFCGNPTRDWPQASLPYASVYSGHQFGVWAGQLGDGRALTIGELAHDGRRYELQLKGAGRTPYSRMGDGRAVLRSSIREFLCSEAMHHLGIPTTRALAVIGSDQPVVREEIETSAVVTRVAQSFVRFGHFEHFFANDRPEQLRALADHVIERFYPACRDADDPYLALLAEATRRTAELVAQWQAVGFCHGVMNTDNMSILGLTIDYGPFGFIDAFDAKHVCNHSDTQGRYAYRMQPRIAHWNCFCLAQALLPLIGLHRDAPSEDARAERAVEDAHAVLGRFPEQFGPALERAMRAKLGLALEREGDAALANQLLEIMDASHADFTLTFRHLARVSKHDARGDAPVRDLFIDRDAFDRWANLYRARLSEEARDDASRAAAMNRVNPKYVLRNHLAETAIRRAKEKDFSEVERLAAVLRRPFDEQLEHDAYAALPPDWASTLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RPB2_ASFB7
Sequence: MEPLRPQITYGPIETVDNEELTEADMLSFISAAVNSTGLIGYNIKSFDDLMDNGIPQIVKQMFNVDITYKDQRDHTEIDKLRESVQIQFNFTDVNIERPQHRNYSQGNKINLLPNKARLCGLSYSGPVNLAAEVILTAHYSNGRQEVKRASIPPFQVSTFPIMRGSNRCHTHHLSKTAKKEIGEDPNEPGGYFIARGGEWVVDLLENIRFNTLHIHYHTMQQGNNEIIRGEFISQPGGAFENSSQIIIRYMTTGAITIEINSTKFSKLRIPWYLIFRMFGMTGDDSIIEQVVFDLESNSPVNTFMIEILEKSIHVLDPIFQPVQHEPNREKIIQFLSEKVSKFVSNPSAYKSDENAVQYLNERQLTILDKILLPHMGQTADTRVRKLRFLGLLIHKILLVIMNVFPPTDRDSYRTKRVHGSGVSLAKAFKAIFNTSVIAPIINGFKELLKQTAFEELTQRNIIEAFSAALSKNTASDLNRSMEQSIISGNKTIMVRQRPIVNRVSTQSLERKNLLNTISALRTVNTHNTTNASKQTERADMMRRVHASYPGYICVAQSADTGEKVGMSKQLAITANVCTAGEVLSLKQRLLSDPAIQQLADVSNKDIVRKGLARVFINGEWIGCCTNAFELAQRYRMFRREGKIVHPHTTIYWDSMVDEVEFWLDVGRLTRPLLIVDNNIEKYNQACYKAAEARKKGDKDWEKHKIPFIQNTRFTSQMAKDILAGTLTLEDLVAQGICEFITPEEAENCLVAFSIIELRKHKHDVTRRFTHVDVPQAILGLAALVSPYANCTQPARVTYETNQGRQTGGWYCFSWPYRVDMNRFFQFYNEMPLVKTIAHNYVIPNGLNTIVAYMIYGGYNQEDSVIVSQSFIDRGGFAGTFYREEKVELESDIESFGKPDPLITKNLKPGANYEKLVDGFVPVGTVVKKGDIIIGKVAKIRGEKDELNKYIDRSVMYGFDEPAVVDAVMRPHGPNDEIFGLMRLRYERNLNIGDKMSSRSGNKGIAALALPTSDMPFTEDGLQPDLIVNPHSHPSRMTNGQMIETTVGLANALQGVVTDGTAFLPINVQLLSERLAQEGLRFNGCQKMFNGQTGEYFDAAIFIGPTYHQRLQKFVLDDRYAVASYGPTDALTGQPLDGKRSHGGLRLGEMEHWVLTAQGAMQTIIEKSHDDSDGCISYICRNCGEPAIYNASHPIYKCMNCDVQADIGMVDSRRSSIVFQHEMRAANVNITSVLSPRVFQPA
What is the function of this protein?
Catalytic component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).  Forms the polymerase active center together with RPB1 (By similarity).  Part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase RPB2 homolog, RPB2 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: SEZ6_XENLA
Sequence: MMPLAGIAWNLMLLFSAVQGLPLQDGEGTQHPDLLNNPPKGSVEPVALEQLVHQAILKKDFLAQDVFFPGTTAIPTRAAPISLTEGVSDASGVLTTAVGGAFSLPPQLSTLIPPSPAPTGGPGPSPEAEEETTTTLITTTTVTTVHSPVLCNNNISESEGLLEAPEYGGSTFFGGLDCTYSVSVYLGYGVEIRVERLNLSKEEALSIEGLEEDRRFLLANETLMAEGQVIRSPTNHVAVRFQTYRATSPGAFRLRYQAFVLSCVFPPRPENGEVTVTDLHPGGAANFRCSAGFTLKGGESLVCLNISRPEWSGKPPVCAASCGGVIRNATVGRIVSPDISTSHSNNHGNNLSCHWLIEAAEGQRLHLHFERVSLDEDNDRLVVRSGSSPLSPVIYDSDIDDVPERGLLSDAQSLYIELISDNPAVPLLLSLRYEVFSESRCYEPFLAHGNFTTTDPLYSPGSLVSFFCNAGYMLEQGPPVIECVDPADPHWNESEPVCKALCGGEISEPAGVILSPDWPQNYGKGQDCVWGIHVQEDRRVLLEIEILNIRRSDALTVYDGDDLTARVLGQYMGVHQRFNLFSSANDVTLQFQSDSNDPVFSLSQGFIIHFKEVPRNDTCPALPEVPNGWKTSSHPDLIRGTVVTYQCEPGYDISGSDILTCQWDLSWSNAPPTCEKILNCADPGEIANGVRRASDPRFPIGSHVQYSCNEGYTLEGSRTLTCYNRDTGTPKWSDRIPKCVLKYEPCLNPGVPENGYQTLYKHHYQAGEALRFFCYEGFELIGEVTITCAPGHPSQWTSQPPLCKVAYEELLDDRKLEVTQTTDPSHQMEGGNIALAIFLPIILVILLIGGIYIYYTKFQGKSLFGFSFPASHSYSPITVESDFNNPLYEAGDTREYEVSI
What is the function of this protein?
May play a role in cell-cell recognition and in neuronal membrane signaling.
What are the official names of this protein?
Seizure protein 6 homolog, SEZ-6.
What is the protein family that this protein belongs to?
Belongs to the SEZ6 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CASK_OREAM
Sequence: MMKSFFLVVTILALTLPFLGAQEQNQEQPICCEKDERFFDDKIAKYIPIQYVLSRYPSYGLNYYQQRPVALINNQFLPYPYYAKPVAVRSPAQILQWQVLPNTAPAKSCQDQPTTMARHPHPHLSFMAIPPKKDQDKTEIPTINTIASAEPTVHSTPTTEAIVNTVDNPEASSESIVSAPETNTAQVTSTEV
What is the function of this protein?
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDKA_FLABI
Sequence: MEQTFIMIKPDGVQSGLVGEIIGRFEKKGFSLKGLKLLTVDRAFAEKHYADLSSKPFFNGLVEYIVSGPVVAMVWEGKNVVTTGREIIGATNPAESAPGTIRGDFAIDIGRNVIHGSDAVESARKVIGLWFPEGVANWSSSLHPWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase A, NDK A, NDP kinase A.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: RK2_GUITH
Sequence: MGIRIYKSYTPGTRNRSSSDFVEITKSKPEKSLLRKKLSCAGRNNRGLITVRHKGGGHKQRYRLVDFKRNKLDIPAIVASVEYDPNRNARIALLHYQDGEKRYILHPKKLAVGDKIYSGINVPIEIGNAMPLYNVPLGTAVHNVELIPGRGGQIVRSAGTSAQVVAKDGQVVTIKMPSNEVRMIYKNCYATIGEVGNADIKNIRLGKAGRKRWLGIRPSVRGVVMNPCDHPHGGGEGRSPIGRAKPVTPWGKPALGVKTRRQNKYSDFCIIRSRN
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RTCA_METBF
Sequence: MLEIDGSYGEGGGQLVRTAVALSAVTGQGIRITNIRKNRPSPGLKQQHLKALETAARICRAQISGLFPGSTEISFVPVEIEGGKYDIDIGTAGSITLLLQCIMPALPFAKEKVELTIKGGTDVAWSPTIDYLQHVTFRALEQLGYSGSITLKEHGYYPKGGGKVSAYFKPCRLREFHFLKEKEDIKGSSHASNLPAHVPLRQAEAASKRLMEAGYPSLIETQSFEAFSIGSGITLWIGYIGGSALGERGLPAEKVGKNAADEIIPELRSGASVDTHLADQLIPYMALAGNSSYTVRELSLHTTTNIWVTEQFLDVKFRIEKKEGLFEVSVS
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADEC_SHIDS
Sequence: MNNSINHKFHHISRAEYQELLAVSRGDVVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYTDAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAKQARQNQYLQVSSCVPAMEGCDVNGASFTLEWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLYVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSYLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: HXBAA_DANRE
Sequence: MALHRHPFVHGAASWDGEQPSPVQLPHISACPFTSSGRKEDPFYFTLDPTGQARQPLDISAFSRIMTDMGSLNSADDHRPETSFYSGHKLLSLNTDTDPESPSLSSHSDSQHLHSLSLSAPCSETDNKHDMQYLAMESTKYPSQWSESRTNRSIITTLSISQRSKDDIEPNNLQTDFTRGDKTPREKTQDVTLENAANGWLSAKAGRKKRCPYSKHQILELEKEFLFNMYLTRERRLEISRSINLTDRQVKIWFQNRRMKLKKMTREHRTRDPGTSFTV
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B10a, Hox-B10.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CRCB2_HALMA
Sequence: MVALESAHLVGAGGALGALCRHYLAGAIQRETFPLGTLTVNAFGSFALGLLTFAGVTGDAALLVGVGACGSFTTFSSFSVETVRLWENGYVALAALNAVGNLACALVGIGLAWGIVRIV
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.