PharMolix/UniProtQA huggingface dataset:
Protein: PSBC_LEMMI
Sequence: MKILYSLRRFYHVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGGMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGLGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLNPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRAFVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDLEPVLFMTPLS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DUSA_ECO57
Sequence: MHGNSEMQKINQTSAMPEKTDVHWSGRFSVAPMLDWTDRHCRYFLRLLSRNTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEARGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDDQDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDFPHLTMSINGGIKSLEEAKAHLQHMDGVMVGREAYQNPGILAAVDREIFGSSDTDADPVAVVRAMYPYIERELSQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADINVLEHALKLVADKR
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U20 and U20a in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(20/20a) synthase, U20-specific dihydrouridine synthase, U20-specific Dus, tRNA-dihydrouridine synthase A.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusA subfamily.
Protein: RNPH_XANOM
Sequence: MTFSRPSGRTADQLRPVRIERAFTRHAEGSVLVSFGDTHVLCTASVENRVPNFLRGKGEGWVTAEYGMLPRSTHTRSDREAARGKQGGRTLEIQRLIGRALRACVDRNALGERTITLDCDVLQADGGTRTAAITGAYVALADAVNLLLKRGEIKKHPLIGAVAAVSVGIYRGEPVLDLDYPEDSDCDTDMNVVMNDGGGFIELQGTAEGHAFRRDELNALLALAEKGMGDLFALQRAALAG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: VIRB7_BRUO2
Sequence: MKKVILAFVATAFLAGCTTTGPAVVPVLDGKPRVPVNKSVPAKPPLAQPNPVDTYED
What are the official names of this protein?
Type IV secretion system putative lipoprotein virB7.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RAB38_MOUSE
Sequence: MQTPHKEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWDIAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLTLPNGKPVSVVLLANKCDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHILANECDLLESIEPDIVKPHLTSPKVVSCSGCAKS
What is the function of this protein?
Plays a role in the maturation of phagosomes that engulf pathogens, such as S. aureus and Mycobacterium (By similarity).  May be involved in melanosomal transport and docking.  Involved in the proper sorting of TYRP1.  Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (PubMed:21187289).  Plays an important role in the control of melanin production and melanosome biogenesis (By similarity).  In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (PubMed:26620560).
What are the official names of this protein?
Ras-related protein Rab-38.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Melanosome membrane. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis. The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization.
Protein: G6PI_ACIB5
Sequence: MSKSIEQFPKDLSSPLIQIKSSVEKNSKLHIKELFALEPERFHNYSVKFDQLFFDYSKQRVTKNILEQLVALAKNKQLTQWINRLFSQDKINCTEQREAMHWALRLPSEYSKFPELTKQVHTQLQRMYTLVEKIHAGQYRGATGEVIQDVVNIGVGGSDLGPHMVTHALADFKVKTAKPLNVHFVSTMDGSQLSDLLHQLRPETTLFIISSKSFGTIDTLSNAQTVRQWLEKALGKHDRVVKSHFIGVSTKAEKMTEWGIIPDNQLLLWEWVGGRYSLWSCIGFPIALTIGIDGFQQLLAGAHAVDEHFQNTSFERNIPVLMALLGIWNNNFLNIQTHAVLPYDGRLKYFAAYLQQLEMESNGKSVQRDGQKVELDTCPIVWGEVGPNAQHAFYQLLHQGTQAVSCDFMAPIQRYNADHFTYVENAEALIEQHHLALSNCLAQSRLLAFGNEALDAAELKNLPIYKQYEGNQPSSTLLLKELNPYSLGMLIALYEHKVFVQSVIWNINPFDQWGVEKGKQIADQLLPILNGVQNDLSTLDASTRGLIKILLGKVDG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_PARL1
Sequence: MKFEKIAFVATEMPEAEAARKALSRRYGDAKPEEADVIVALGGDGLMLQTMHQHMKRRIPIYGMNRGSVGFLMNEYRDDNLTERLAAAECATIHPLRMRASLADGSCHEALAINEVALFRETYQAAKIRISIDGKTRMEELVCDGVLVATPAGSTAYNLSAQGPIVPIDAALLALTPISAFRPRRWRGALLSHRAQLRFEILEAEKRPVSAVADHTEFRQVREVEVEEDGSIDMLMLFDPDHGLEERIITEQFLY
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_PARP8
Sequence: MAVQQNKKSPSKRGMHRSHDFLNAAPLAVEPSTGEVHLRHHISPNGYYRGKKVVKTKND
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: PFF1_PODAN
Sequence: MINPISFRPGPVTFWTTLVYLALLIPIVIINETVPPAPAAADDGKIEGVNLTEAWLDLTRITRGYHPYNSRFNEEVRGYLLGRVGEILEGSGVGGKKGNVTVFDDLRSNVTGLMAGSVVPTPGSAQVAAYFEGTNILVYVRGKGDDEGDWWRRSAEGGEMEGVRKNERGLVLVNAHYDSVSTGYGATDDGMGVVTCLQVIKYFAHPDHQPERGIVVMLNNGEEDYLYGARALGQHPLNPYIHTFLNLEGAGAGGRANLFRTTDREVTAAYAGTSDPFGTVIASDAFGLGFIRSGTDYSVLYDVYGQRGLDLAFFKPRSRYHTNRDDATHTSKASLWHMLSAAIHTASKLSGDTGDTFVGARPDGARNKVRNGSPSNGVWFDLFGKGFVNFGLRGMFAWSLTVLVATPLILVLATYILHKLDKYYFFTSSVRTYDQPDFEPVLVGGWKGAFRFPFAFIVSGALSLAVAFLMRKVNPFIIYSHRYSVIAMIFSLFYFTFWSIMRGANFARPSALHRGYVNIWLFILGWATLVAVTVTEDRFKLGAGYPIVFLQTAVCLTTFLTLCELFALPKKTAWGQQVREDHEVHDYYQPQSGNNNTRTESPPPLPQIPHQPSLVPPATRDSNASTLRQGDGNDTDDEDAAVPTERTPLVGGGNATSEHFRTTFATTYRRSITALVNGARKYGQDGDEPFEHEQAWSGRLPSWLWFFQFLILGPFTIILAAQTGLMLVDAVHQTGADGSNLLLPYLIVFAFTVLVLLPITPVIHRISHHIPVFLLVVFVGTLIYNLVAFPFSEESRYKVYFVQQIDLDTADNRVCYNGVDEYVHKIIAELPSASGRNVTCGESKRAELVSCCYDGVDVAPRLGSETPEEDTPIEEIYKSLATVTATRGEGNKAQLEIEADNTKACFLEFKQPISGFNVQGGSEWDDRFGQFPEGGIKQLKLWHRQRGERWVVDVEWKDAEKLEGQVVCAWSDANEAGTIPALDEGLRYSPVWAAITKFAEGLVEGRKGFSV
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: BAME_YERPE
Sequence: MITMRCKMLTAAAVMLAMLTAGCSTLEKVVYRPDINQGNYLSPIDASKIHKGMTQQQVAYTLGTPMLQDPFGTQTWFYVFRQQPGHEKITQQTLTLTFDSSGVLTDIKNEPALTGS
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamE.
What is the protein family that this protein belongs to?
Belongs to the BamE family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: OGT1_HUMAN
Sequence: MASSVGNVADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNADSSNTALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA
What is the function of this protein?
The mitochondrial isoform (mOGT) is cytotoxic and triggers apoptosis in several cell types including INS1, an insulinoma cell line.
What are the official names of this protein?
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly localizes to the nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion. Membrane. Note=Associates with the mitochondrial inner membrane. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus. Cell membrane. Mitochondrion membrane. Cell projection. Note=Mostly in the nucleus. Retained in the nucleus via interaction with HCFC1 (PubMed:21285374). After insulin induction, translocated from the nucleus to the cell membrane via phosphatidylinositide binding. Colocalizes with AKT1 at the plasma membrane. TRAK1 recruits this protein to mitochondria. In the absence of TRAK1, localizes in cytosol and nucleus (By similarity). SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm. Nucleus.
Protein: SPAQ_SHISO
Sequence: MSDIVYMGNKALYLILIFSLWPVGIATVIGLSIGLLQTVTQLQEQTLPFGIKLIGVSISLLLLSGWYGEVLLSFCHEIMFLIKSGV
What is the function of this protein?
Required for surface presentation of invasion plasmid antigens.  Could play a role in preserving the translocation competence of the Ipa antigens.  Required for invasion and for secretion of the three Ipa proteins (By similarity).
What are the official names of this protein?
Surface presentation of antigens protein SpaQ, Protein spa9.
What is the protein family that this protein belongs to?
Belongs to the FliQ/MopD/SpaQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNZ_STAAT
Sequence: MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQTLIQNEDTPNFNFVKDFDSFKI
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RIMP_BURMS
Sequence: MQLTELIETTVTGLGYELVDLERTGRGMVCVYIDQPAGITIDDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFTRFAGSEAVITLKKPLDGRKTYRGILHAPNGETIGLEFERKKGEAAMLDFTLADIDKARLIPHVDFRSRKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_CITK8
Sequence: MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVMGFSDLMANFARIQQANILIRGLRAVADFEYEMQLAHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMDKLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4217_RHOPA
Sequence: MDWNRVEGNWKQFKGNVKEKWGKLTDDDLDVIEGRRDQLEGKLQERYGYAKDQVRKDVDDWFTTLK
What are the official names of this protein?
UPF0337 protein RPA4217.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: RECR_VIBA3
Sequence: MRTSHMLEHLMEALRCLPGVGPKSAQRMAFHLLQRDRKGGLQLAEALSQAMTEIGHCNECRTFTEEETCHICTNPKRQDNGQICVVESPADIAAIEATGQYSGRYFVLMGHLSPLDGIGPSDIGLDVLDYRLRRGDITEVILATNPTVEGEATAHYIAELCNAHEVNASRIAHGVPVGGELELVDGTTLSHSLLGRHKI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: DNAK_CARHZ
Sequence: MGRIVGIDLGTTNSCIAVMEGGEVIVIPNAEGGRTTPSVVAFGKNGERIVGQVAKRQAITNPERTVISIKRHMGTNYRVKIDDKEYTPQEISAMILQKLKQDAEAYLGEKIEKAVITVPAYFTDAQRQATKDAGRIAGLEVLRIINEPTAAALAYGLDKEGEQTILVYDLGGGTFDVSILEIGDGVFEVKATAGNNRLGGDDFDQRIIDWLVENFKKEHGIDLRNDKMAMQRLKEAAEKAKIELSGVLETQINLPFIAANQNGPLHIDVTLTRAKFNELTADLVEATMGPTRQALADAGLKPEDIDKILLVGGSTRIPAVQEAIRKFFNKEPHKGINPDECVAIGAAIQAAVLAGEVKDVVLLDVTPLSLGIETLGGVFTKLIERNTTIPTSKSQIFTTAADNQTSVEIHVLQGERPMAADNVSLGRFTLTGIPPAPRGVPQIEVRFDIDVNGIVHVSAKDLGTGREQSITITNTSNLSEAEIKRMVEEAERYAEEDRKRKEEVETRNQADSLIYQAEKTLKDFKDKANPDLVARVEKAIAELREAMNSKDVQLMRAKMEELTKPLYELTSSIYQQSANQNQTQTGTNTQGNVYDADYKVNDDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL6_SHEB9
Sequence: MSRVAKAPVSIPAGVEVTLNEQTLTVKGGKGSLTRVINNAVNVVIEAGVVKFLPVEGVSNAWAQAGTTRALVNNMVVGVSQGFERKLKLVGVGYRAKLVGSDIDLTLGFSHPLVHKLPAGVTAECPSQTDIVLRGVDKQLIGQVAAEIRGYRPPEPYKGKGVRYDDEVVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RSMA_FRATN
Sequence: MQYKTKAKKSLGQNFLQDENIIRKIVQLANIKKHDIVIEIGPGLGALTRYLLSSSNNVSVVEFDASVIDTLIANCQKYGTPHIYNQDFLKFDISSLENSSNQKIKLIGNLPYNISSPILFKVIKDSDKIVDAHFMLQKEVVERIVSLPNSKSYGRLSVILQYHFDCSMILKIPPEVFYPQPKVDSAILRLKPKNSKELLKNYNFFEEIVKQSFAQRRKTLHNNLKSILKERKIDPSTLPVDTNLRAENLSVGDFVSLANFLS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDH15_ARATH
Sequence: MNLFRFCSGLKVLGYFMILLVVAVVGVSYYAVVVSTWWPILIRGDHGALSALAALIIFVFHFLLIMLLWSYFTTVFTDPGSVPEHFRREMGGGDSLEAGTSTDQGAFGSLGYCTKCRNVKPPRCHHCSVCQRCVLKMDHHCVWIVNCVGARNYKFFLLFLFYTFLETMLDVIVLLPSFIEFFSQAIKHSSSPGKLASLVLAFVLNFAFVLSLLCFVVMHISLLSSNTTSVEVHEKNGEVRWKYDLGKKKNFEQVFGKKKAFWLLPLYSKDDIDNITSLEGLEFPTCSDIDP
What is the function of this protein?
Palmitoyl acyltransferase.
What are the official names of this protein?
Probable protein S-acyltransferase 12, Probable palmitoyltransferase At4g00840, Zinc finger DHHC domain-containing protein At4g00840.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RFC2_DICDI
Sequence: MTTTTTTTTNTNTTNLDPLLPWVEKYRPILIKDIVGNEETVSRLESISKDGNLPNIIISGPPGTGKTSSILCLARALLGANYKEAVYELNASDDRTLDVVRDKIKSFAMKKVTLPAGRHKIIILDEVDSMTSGAQQALRRIMEIYSGTTRFAFACNQSTKIIEPIQSRCAVLRFTRLSDSQILTRLREVVQIEKVPYTDDGLAAIIFTAEGDMRQALNNLQATHSGFGLINAENVTKVCDQPHPLIIKQIIALCAKSDFKEAYPFLKKLWDDGYSSIDIISALFSITKSSNNIPEYQKLEFLKEIGFCNLRATTGVNTLVQLTGLLSKLCLVSIKMKN
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1.
What are the official names of this protein?
Probable replication factor C subunit 2, Activator 1 subunit 2.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS4_BART1
Sequence: MSKRETTKYKIDRRMGENIWGRPKSPVNRRDYGPGQHGQRRKGKLSDYGVQLRAKQKLKGFYGDISEKQFHKTYVEAARRRGDTGENLIGLLESRLDAVVYRAKFVPTIFASRQFINHGHVNVNGRRTNIQSYRCKPGDVIEVREKSKQLVLVLESVQLAERDVPDYIEADHKQMKATFTRIPAFADVPYAVQMEPNLVVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: KCY_STRTD
Sequence: MKDIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYLALQNGLTEENVPEILDQLSQYPISFGKAADGSPKVYVGDVDITHPIRDNQVTNNVSWVAAIPEVRQELVSQQQRIAQEGGIIMDGRDIGTVVLPDAELKIFMIASVDERAERRYKENIEKGIPADLETLKKEIAERDYKDSHREVSPLRPAEDAITFDTTGVSIDGVVEFIQEKAKKIIDKG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPR29_CAEEL
Sequence: MDFTENEEEYEHWTHIERRVPFQGYRTYVASTYISFNVVGFVINAWVLYVVAPLLFAPAIKVPKSILFYIFALCVGDLMTMIAMLLLVIELVFGTWQFSSMVCTSYLIFDSMNKFMAPMIVFLISRTCYSTVCLDKTRGEKAATLKYAIIQFCIAFAFVMILLWPVFAYSQVFTFYMNPNSTAQEVTVMRKCGFFPPPQIEFWFNLIACITSYAVPLFGIIYWYVSVPFFLKRRALTTLVASSSMDAALRKVITTVLLLTVIYVLCWTPYWVSMFANRIWIMEKKSIIIISYFIHLLPYISCVAYPLIFTLLNRGIRSAHAKIVADQRRRFRSLTDEASSQIRTAIRTIPGTKMKKNEFLTRTEEISSDKIASEAVSEFREGLPSQTSFPDETLL
What is the function of this protein?
Not known.  Putative receptor.
What are the official names of this protein?
Probable G-protein coupled receptor npr-29.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FGF1_HUMAN
Sequence: MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
What is the function of this protein?
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.  Functions as potent mitogen in vitro.  Acts as a ligand for FGFR1 and integrins.  Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades.  Binds to integrin ITGAV:ITGB3.  Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling.  Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (PubMed:18441324, PubMed:20422052).  Can induce angiogenesis (PubMed:23469107).
What are the official names of this protein?
Fibroblast growth factor 1, FGF-1, Acidic fibroblast growth factor, aFGF, Endothelial cell growth factor, ECGF, Heparin-binding growth factor 1, HBGF-1.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59.
Protein: KAD_WOLPP
Sequence: MIITIFGPPGSGKGTQSSLLIAKYNFKLVSVGDLLRNIISSESKLGKGIKDTVESGNLIQDEVICKLLCDQLALIDGDFLLDGFPRNLNQAHFLTQVLQKRCNRDVDLVIELQLDDNIAIDRLKDRLTCLDCKSIYSISSFKNTTCAKCKSTRLEKRIDDANMLAINKRIREYHSQIEGLREYYKDKLLTINANLSVDRVMQEIESKISCNLI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.