PharMolix/UniProtQA huggingface dataset:
Protein: SPA5L_HUMAN
Sequence: MAPDSDPFPEGPLLKLLPLDARDRGTQRCRLGPAALHALGARLGSAVKISLPDGGSCLCTAWPRRDGADGFVQLDPLCASPGAAVGASRSRRSLSLNRLLLVPCPPLRRVAVWPVLRERAGAPGARNTAAVLEAAQELLRNRPISLGHVVVAPPGAPGLVAALHIVGGTPSPDPAGLVTPRTRVSLGGEPPSEAQPQPEVPLGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAELLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQRGSRAPESRVVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPTLKQRKEILQVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLHSEKNQDNPVIDEIDFLEAFKNIQPSSFRSVIGLMDIKPVDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGVLLYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILFLDEIDSILGARSASKTGCDVQERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRSVMIIAATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLENLAAETCFFSGADLRNLCTEAALLALQENGLDATTVKQEHFLKSLKTVKPSLSCKDLALYENLFKKEGFSNVEGI
What is the function of this protein?
ATP-dependent chaperone, which plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles (PubMed:35354024).  Acts together with SPATA5, C1orf109 and CINP (PubMed:35354024).
What are the official names of this protein?
Ribosome biogenesis protein SPATA5L1, Spermatogenesis-associated protein 5-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. AFG2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Nucleus.
Protein: SETD3_DANRE
Sequence: MGKKSRVKTQKSGTGATAAVSPKEMMNLISELLQKCSSAAPSPGKEWEEYVQIRALVEKIRKKQKGMSVSFEGIREDFFSELMAWAAECRASCDGFEISNFADEGYGLKATKDIKAEELFLWIPRKMLMTVESAKNSVLGPLYSQDRILQAMGNVTLALHLLCERANPSSPWLPYIKTLPSEYDTPLYFEEEEVRHLLATQAIQDVLSQYKNTARQYAYFYKVIHTHPNASKLPLKDAFTFDDYRWAVSSVMTRQNQIPTADGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALKDYKEGEQIYIFYGTRSNAEFVIHNGFFFEDNAHDRVKIKLGVSKGERLYAMKAEVLARAGIPASSIFALHCSEPPISAQLLAFLRVFCMTEEELRDYLVGDHAINKIFTLGNTEFPVSWENEIKLWTFLETRAALLLKTYKTASEEDRSMLEKPDLSLHSRIAIKLRLAEKEILEHAVSCGRAKRLHFQKQLDEGAPLPLYEESDIALLENADAKLPIILRKLEEEEEEHVEEMNQLTPDAVCMNSSKIPVLNGQCKDLNGTQEDPPGGGAVVKEIEKHDPSAKRTEGEPKDAGK
What is the function of this protein?
Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'.  Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin.
What are the official names of this protein?
Actin-histidine N-methyltransferase, Protein-L-histidine N-tele-methyltransferase, SET domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_RICCK
Sequence: MAIMSDKWIKEAVINQSMIKPFVEKQVRVHNKDKIISYGLSSYGYDARVSNEFKIFTNINSTTVDPKNFSEYNLVDREVDVCIIPPNSFALGRTIEYFKVPRDILVICVGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGACQFLFLNSDQMCDTSYADRQGKYMKQVGVTLPLT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PPAC_OCEIH
Sequence: MVKTVIFGHKNPDTDTICSSIAYADLKTKLGHEVAPVRLGEVNLETQFALDKFNIHAPELIERVEDGAEVILVDHNEFQQSVDNIENATIREVIDHHRISNFETKEPLYFRAEPVGCTATILNKMYKENDISVDKNIAGILLSAIISDSLLLKSPTCTEEDVQAAHELAEIAGVDLESYGLDMLKAGADLSDKTVKDLITMDAKEFAMGNAKVEIAQVNAVDTNEIYKLHDKLVEVITSRINDNDLDLFLFVVTDILNNDSEVLAIGNGKDKVNAAFNVTLDSTNRALLKGVVSRKKQIVTVLTEQFK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCAA_STAES
Sequence: MSQCPNCGHQVKDDTSQCPNCGQLLTKKKKRKIKDQSSQSSNENSTNIRLRKIVPIGISVFILILIIVLFFLLRNYNSPNAQAKILVNAVDNNDSQKVATLLSTKNKKVDDVEAQQYINYVKKEVGIKKYIRDINNTVDKLNKSNSSVASYIQTKSGQDVLKISKNGTKYLIFDNMSFTAPTKKPIIKPKVETKYEFRTSGKKKTVIAEANKNTPLGEFIPGTYHLPAKKITENGTFNGHLNFDFRESHSETVDVAEDYDQSFINIKFKGANKLSDKSEKVQINDRTFTYSHSKEFGPYPKTKDITISATGKAKGKTFSSETKTISADDLKDNTKVTLEFDSDKINSYVEKKEKEENSLKNKLTEFFTGYATAMNSAFNMNDFNFISSYFKKNSSIYTSMKSNFQNRTNVTMISPQVLSVHRNGHTVRTTIQHIDHIGNYINKDYELEIDNDDSNMQLVKEL
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CYB_ARAJA
Sequence: MINIRKTHPLMKIVNNAFIDLPTPSNISSWWNFGSLLGICLILQILTGLFLAMHYTXDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNMGVILLLTTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGIPSDADKIPFHPYYTIKDILGAMMLILSLMLLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLAXVLSILILVLVPFLHTSKQRSMMFRPISQCMFWILVADLLTLTWIGGQPVEHPYIXIGQLASIMYFLIILVMMPVASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PRMA_RUMCH
Sequence: MKWYEVRVSTTDEASDAVSEMLTTMGAGGVAIKDPFDIKKEILKPNSLDYADDEFLESLGEDVVIQAYFQSGNDIDKLLKQINEGLVNISQFLNIGKGLEGYNEVDDEDWSTAWKKYYKPLQLTDRIVIKPTWEDYSPNADEIVIQMDPGMAFGTGTHETTQMCSILLDKYMKDDTEVLDIGCGTGILSIIAAKLGAKQVEAIDIDEVAVKVARENIELNQEITKVSARKAVLSDLKAEEHKYDIIVANIIANVIIDLSSQIPYYLKKESLFITSGIIKERKQEVIDACEKNGMSRIETLEMGEWVAMVFKCPDTL
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSTM5_RAT
Sequence: MRPPRCVGRTQGIPLGLLAFWVATARCLQSQGVSLYIPRSAINATVQEDILLSVDYICHGVPTIEWEYTPNWGVQKIVEWKPGTPANVSQSHRDRVCTFDNGSIQLFSVGVRDSGYYVITVTEHPGSSQSGTILLHVSEIRYEDLHFVAVFFALLAAVAVVLISLMWVCNQCAYKFQRKRRYKLRESTTEEIEMKDVEC
What is the function of this protein?
Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics.  Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia.  In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution.  Promotes formation of unstable neuronal spines such as thin and branched types.  Regulates neuronal morphogenesis and migration during cortical development in the brain.
What are the official names of this protein?
V-set and transmembrane domain-containing protein 5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Cell projection, axon.
Protein: Y781_AGRFC
Sequence: MSFSTLMDKRERGSFDSQFLIAMPGLDDGNFARSVIYICAHSDAGAMGFIINRPQQITFTDILLHLKLVDSNDAIMLPNRTREFPIQCGGPVESGRGFVLHSDDYLSESSIPVSDDISLTATLDIVRAISNGRGPQKATMMLGYAGWGPGQLENEIANNGWLNCPAAEELIFDRGLDNKYERALALMGVDARMLSTDAGHA
What are the official names of this protein?
UPF0301 protein Atu0781.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: MLR_LUMTE
Sequence: AKDKEKKEKKDKKKDDAPAEEAPAAAAAPAEEAAPTPSAAPIHKVGNVFALFKQNQIQEFKEAFTMIDQDRDGIIGPDDLGNIFQQIGREVDPKVVKEMLAESAEKLNFTHFLTLFGEKLHGTDTEGTLRDAFALFDEDKLGYLLEEYVKDLLTNVGDQYNKDEIKQVWKEAPIEGGKFDYVKFVRLIKRGKEEE
What is the function of this protein?
Plays an important role in regulation of muscle cell contractile activity.
What are the official names of this protein?
Myosin regulatory light chain, striated muscle, 25 kDa isoform, LC25.
Protein: KGUA_BACAN
Sequence: MRSRRGLLIVLSGPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKEREEFEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGVFIFLAPPSLSELKNRIVGRGTETEDVIENRLTVAKEEIDMMDAYDYVVENDQVELACERIKAIVVGEHCRRERVAKYYKEMTEGL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_PSEA6
Sequence: MAKAKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAASAFDQIDNAPEERERGITISTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPFMVVFMNKCDMVDDEELLELVEMEVRELLSEYEFPGDDLPVIQGSALKALEGEEQWEAKIIELAEALDSYIPEPERDIDKPFLLPIEDVFSISGRGTVVTGRVERGIVNTGDAVEIVGMKDTTTSTVTGVEMFRKLLDEGRAGENIGALLRGTKREDVERGQVLAKPGSINPHTQFEAEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGAVELPEGVEMVMPGDNLKFVVELIAPIAMDEGLRFAIREGGRTVGAGVVAKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y121_ADE02
Sequence: MSAAALALAAAEEGGASAAAPDASGKSKKGARPCFRRNLQAGSCMTGRQTPVRRSPAGPRLEPGVLRLNPWKITLRLQGASHLMLSLSSLTAYAARGQWPKKLAQQPPRLEGSQKERSPVV
What are the official names of this protein?
Uncharacterized protein F-121.
Protein: PLPP2_RAT
Sequence: MERRWVFVLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTITHGLMAGVIITATVVLVSSGEAYLVYTDRLYSRSDFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDPDWSRVNCSGYVQVEVCRGSPANVTEARLSFYSGHSSFGMYCMLFLALYVQARLCWKWARLLRPTVQFFLVAFAIYVGYTRVSDNKHHWSDVLVGLLQGALVACLTVCYVSDFFKSRPPQSCQENEESERKPSLSLTLTLGDRP
What is the function of this protein?
Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P.  Has no apparent extracellular phosphatase activity and therefore most probably acts intracellularly.  Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound.  Through dephosphorylation of these bioactive lipid mediators produces new bioactive compounds and may regulate signal transduction in different cellular processes (By similarity).  Indirectly regulates, for instance, cell cycle G1/S phase transition through its phospholipid phosphatase activity (PubMed:16467304).
What are the official names of this protein?
Phospholipid phosphatase 2, Lipid phosphate phosphohydrolase 2, PAP2-gamma, PAP2-G, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c, PAP-2c, PAP2c.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MOCOS_DROYA
Sequence: MAPYRPEFSAAEQSRIDAEFSRLARNKSVYLDHAGTTLYAENQVTAAAEQLQRNVICNPHTCRLTGDFVDQVRFKILEFFNTTAEDYHVIFTANATAALSLVAENFDFGSTGDFHFCQENHTSVLGMRERVRANGIYMLKEKEISGGELKKNGTVHKVSGKTGNSLLTFSAQCNFSGYKIPLDTIEKIQIDGLSKPGKQLWGSLGENKENTHNDYYICLDAASFVATSPLDLKKYRPDYVCLSFYKIFGYPTGVGALLVSRRGADVFQKRRFFGGGTINYAYPHAMDYQLRETFHQRYEDGTLPFLAIVGLLEGFRTLERLVPKTDEFSTMERISRHVFGLAKYLEDQLRQLQHPNGEPLVELYNKVGYQDKSRQGGIVAFNVRTESGSFVGFGEIACVAALHGILLRTGCFCNIGACQYYLNLDEDAMDTIYKRAGRICGDYFDLVDGQPTGAVRVSFGYMTTFQDVEQLLQMLRSSYLATKPLQRIQFIEEQAEQLPPLLKERVQLLRPKLLQMAIYPVKSCAAFKIELEGSWPLTDQGLRYDREWMIVDMNGMALTQKRCTELCLIRPVIKVDQLELQFGDNSHFSVPLSLEDQAADSAKCVSKVCRQPVEGLDCGDGVAQWLSENLGLEGLRLLRQSGQRNSSKDQQKLSLVNQAQFLLLNKSSVRSLQFEEPLDETVDRFRANIIIDTGSAFEELTYKALSIGGIQFQVEGPCQRCDMICINQRTGERSPETLTTISRLQKGRMRFGIYITRIPQDTKELEAKEHMTCGDVVLVE
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase, MCS, MOS, MoCo sulfurase, Molybdenum cofactor sulfurtransferase, Protein maroon-like, Ma-l.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: METR_HAEIN
Sequence: MKPTFLEFRHLKTLLALKETGSVSLAAKRVYLTQSALSHQIKLIEEQFGLPLFERKSNPLRFTSAGERLIRLANEVMPKVIDAERDLARVKHGDAGQLRIAVECHTCFDWLMPAMDEFRQHWGLVELDIVSGFHTDPVGLLLSHRADWAIVSEIEHNDDVIFKPLFSYEMVGICSKNHSLAEKDIWEAEDFIDETWVTYPVPDDMLDLWRKVLKSKGINPTRRTTELTIAMIQLVASRRGIATIPYWAALPYLEKGYVVARKVTKEGLYSNLYAAIRKEDESLSYLEDFYQTVKSQSFSTLPGLSVLNL
What is the function of this protein?
Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes.
What are the official names of this protein?
HTH-type transcriptional regulator MetR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_PROM5
Sequence: MKLIPAIDLMNGKCVRLFKGDFNKRKDFSRKPYEQAKYWEEQGAKCIHIVDLDAAKSGYPSNDQSIKKIAKEVNIPIQIGGGIRSLERIEQLFSYGVDKVIMGTSAIENKELVKNLSTKFPRRIIIGIDAKDGKVSTRGWIEQSDVLATDLVKEFSKFEIASFIVTDINTDGTLEGTNEVFIKKILEITDIPVIASGGVGAISDLLSLTKFEHLGLCGVIVGKALYENKFKISEANNILSPERLQDIPINKDYFA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_CAMJD
Sequence: MQVEVKLKENAYKVYIDELEELEFDTKVFILSNPKISGLHLKTLLSKIKAKEISIATVKDGEEYKNLSTMEEILSQMFNSKLDRKSVLISFGGGVISDMGGFAASIYQRGIDFINIPTTLLACVDAAVGGKTGVNNNFGKNLIGTFYQPKAVYCESSFLKTLSSRELAAGMAEFIKMAAIFDDSMLDFIEKIDEKSFLNATCENEIFTQIIAKSIELKARVVEQDEKESGLRMLLNYGHTFAHVIENFTDYKLYLHGEAVAIGMVMANQLALNLGLLDKMQSQRIKDILLKFGLPISYKINSVDEFYEAFFMDKKSSNKKINFVLASPLGKGLIKGDISKEDIITTLREFQ
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_CORGL
Sequence: MRPELSQYKHLSAGKVREIYEIDDKHILMVASDRISAYDFILDTEIPDKGRVLTAMSQFFFDTIDFPNHLAGPADDPRIPEEVLGRAMVCKKLNMLPFECVVRGYLTGSGLVEYKQTSSVCGVELPEGLVESSQLPEPIFTPATKADIGDHDINVSFDVVEERLGEARANQLRDASIAIYKAAAEIARDRGVILADTKFEFGIDEDGTLVLGDEVLTPDSSRYWPLEGYEAGSVQPSFDKQFVRNWLTGPKSGWDKDSGLEPPALPGSVVEATRERYIEAYELISGQKFCQWIGSCV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MIAB_BIFAA
Sequence: MMTEAERASKLAEPAANDTPTRGKGVFYVHTLGCQMNVHDSERIAGVLEADGYVPATEEQYLNHDIDLIVMNTCAVRENAAERMYGTIGLWAELKRERPNLQIAVGGCMAQLDREKIAKKAPWVDAVFGTKNIGSLPQLLDQARIEGHAQVKVQEELNYFPSQLPTDRASKVSSWVAISVGCNNTCTFCIVPTTRGKEHDRRPGDILAEIRQCVDEGAKEVTLLGQNVNSFGYGIGDRFAFSKLLRACGEIDGLERVRFTSPHPAAFTDDVIAAMAETPNVMHQLHFPLQSGSDRILRAMRRSYRSAKFLDILRKIREAMPDAQISTDIIVGFPGETEEDFQETLRVVEEARFASAFTFIYSPRPGTPAAEMEQVPHDVVQDRFERLVALQERITEENLKTFEGRDVEVMVTGASGKKDAATHRVTGREKTGVLVHVGVPEGEPMPQVGDFVTATVTHAGRHNLIADPNPEAGQTYAVRH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COTB2_STRMJ
Sequence: MTTGLSTAGAQDIGRSSVRPYLEECTRRFQEMFDRHVVTRPTKVELTDAELREVIDDCNAAVAPLGKTVSDERWISYVGVVLWSQSPRHIKDMEAFKAVCVLNCVTFVWDDMDPALHDFGLFLPQLRKICEKYYGPEDAEVAYEAARAFVTSDHMFRDSPIKAALCTTSPEQYFRFRVTDIGVDFWMKMSYPIYRHPEFTEHAKTSLAARMTTRGLTIVNDFYSYDREVSLGQITNCFRLCDVSDETAFKEFFQARLDDMIEDIECIKAFDQLTQDVFLDLIYGNFVWTTSNKRYKTAVNDVNSRIQ
What is the function of this protein?
Catalyzes the cyclization of the linear isoprenoid intermediate geranylgeranyl diphosphate to tricycclic cyclooctat-9-en-7-ol in the cyclooctatin biosynthesis pathway.  Cyclooctatin is a potent inhibitor of lysophospholipase.
What are the official names of this protein?
Cyclooctat-9-en-7-ol synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RL31_PSEAE
Sequence: MKADIHPTYEAIEATCSCGNVIKTRSTLCKPIHLDVCSECHPFYTGKQKVLDTGGRIDRFKQRFGVFGATK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: BIOW_LYSSH
Sequence: MLETCYSIRMRAAEKNLEGGEKHISGGERIGSEFQIEPIVKQLLNKARNHSRGDADFIQITVEKLTGDQILYMPPLEITTIDESSIERAHKEARSILTSVGVSKQAQNVAFHLLASNQNLRGAILLHSQTGLRLDNRGLKGVRVSRIDWQDADVGYNERVREALALATKVANSPYTIAELCWSDDPEYVTGYVSNHEIGYVRITPLKREGCESGGRIFFVSDEVELESYIHYLEREPILIRGHLK
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: GAL1_ECO55
Sequence: MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKHLQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGGGFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_PROM9
Sequence: MKSILEQLSSMTVVVADTGDLDSIKKFQPRDATTNPSLILAAAKNPDYVKLIDKAIESSENTLPNGFSEIELIKETVDQVSVFFGKEILKIISGRVSTEVDARLSFDTEATVKKARKLINLYKNFGIEKERILIKIAATWEGIKAAEILEKEGIKCNLTLLFNFCQAVTCANANITLISPFVGRILDWHKAKTGKTSFIGAEDPGVISVTQIYKYFKEKGFKTEVMGASFRNLDEIKELAGCDLLTIAPKFLEELKREKGVLIRKLDASTKINNSIDYKFEEKDFRLSMLEDQMASEKLSEGITGFSKAIEELEELLIERLSEMKNHKLISAN
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HES5_RAT
Sequence: MAPSTVAVEMLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLKHSKAFAAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQRPPAPAAPVKETPTPGAAPQPARSSTKAAASVSTSRQSACGLWRPW
What is the function of this protein?
Transcriptional repressor of genes that require a bHLH protein for their transcription.  Plays an important role as neurogenesis negative regulator (By similarity).
What are the official names of this protein?
Transcription factor HES-5, Hairy and enhancer of split 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: KEX1_AJEDR
Sequence: MGFSETRAYSAWGAWSTWLTICLALANLLPVTAKSAADYFVDSLPGQPEGPLVKMHAGHIEINPETSGNFFFWHFANSHIADKPRTIVWLNGGPGCSSEDGALMEIGPYRVTDDHMLNRTDGSWDEFANLLFVDQPVGTGFSYVSTGAYVSELDEMTSQFVTFMEKWFELFPHYEKDDLYFAGESYAGQYIPYIARAILDRNKKESVQAQNRQWNLKGLLIGNGWISPRHQYLSYLPYAYREGIIQGGTDASLRVEATISKCMKKLNVEDTTGTIHIADCEDILQTIVDETHKGNRCINMYDIRLTDAYSACGMNWPPDLKNIEPYLRYKNVTEALHINSDKQTGWTECSGAVGGNFRALKSKPSVELLPRLLEEGLPILLFSGQKDLICNHMGTEDMIKDMKWSGGTGFELSPGVWAPRQDWTFEGDSAGFYQQARNLTYVLFYNASHMVPFDYPRRTRDMLDKFIGVDITDIGGNPADSRIGGEKGPTTSVGGHPNSTTAAEREKEKMKSAAWKAYYKSGEVALIVVAIAAIIWGVFIWRSRRQKLRNPSHEYRGIYPMLGSSSSGSLPRFSNKRGRSADDVEAADFDETELDERPSRAVSSRSSREHEPYAIGEEDGSDREGEGSDERRRLVDKS
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: CAPSD_CMVII
Sequence: MDKSESTSAGRNRRRRPRRGSRSAPSSSDANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCKPGYTFTSITLKPPKIDRGSYYGKRLLLPDSVMEYDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVAAISAMFADGASPVLVYQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDALETDELVLHVDVEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: CUTC_SERP5
Sequence: MIKLEVCCYSVDCALTAERAGADRIELCASPSEGGLTPSYGSLRLARDRVSVPVHPIIRPRGGDFCYGAVDFDVIKHDIAQIRDMGFAGVVVGMLDEEGHIDLQRMREVMRLSGNMAVTFHRAFDMCQNPMVALSQLTQLGVARILTSGQQQNAELGLPLLRDLLQASQGPVIMAGAGVRLSNLHKFVDIGIQELHSSSGHAVPSTMRYRKAGVTMCSDSEFDEFSHYCVDGEMVEAMKNSLALVDPLVQSA
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCCT_SALG2
Sequence: MKTGALATFLALCLPVTVFATTLRLSNEVDLLVLDGKKVSSSLLRGAESIELENGPHQLVFRVEKTIRLPGNEERLYISPPLVISFDTQLISQVNFQLPRLENEREASHFNAAPRLALLDGDAMPIPVKLDILAITSTAKVVDYEIETERYNKSAKRASLPQFATMMADDSTLLSDVSELDTVPPQSQTLTEQRLKYWFRLADPQTRHHFLQWAEKQPPS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.