PharMolix/UniProtQA huggingface dataset:
Protein: MDH_PARL1
Sequence: MARKKIALIGGGQIGGTLALLAGLKELGDVVIFDIAEGLPQGKALDLAQTGPVEGYNTALSGANDYKGIKGADVVIVTAGVPRKPGMSRDDLLGINLKVMKQVGEGIAKYAPNAFVVCITNPLDAMVWALRQFSGLPHNKVVGMAGVLDSGRFRLFLAEEFGVSVEDVTAFVLGGHGDTMVPLPRYSTVAGIPLPDLVKMGWTTKEKLDKIIQRTRDGGAEIVGLLKTGSAFYAPAASGIQMAEAYLKDQKRVLPCAAYINGQYGVKDMYVGVPVVIGAGGVERIVEIDLNGSEKKQFMNSVNAVKGLVDACKKIDPAVAKGAAPAKKAAKKK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: WIPF1_RAT
Sequence: MPVPPPPAPPPPPTFALANTEKPSLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGAGGGYGGGSGGGGGGGSSGGGGNFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPILPPGGRATSAKPFSSPSGPGRFPAPSPGHRSGPPEPPRNRMPPPRPDVGSKPDSLPPPVPNTPRPIPSSLHNRGSPAGLGAPRPPFPGNRGAAFGAGSVRQNLSSSSSPFPRPPLPPTPSRALDDKPPPPPPPVGNRPSMHREAVPPPPSQNSKPPVPSTPRPGAGSQAPPPPPPSRPGPPPLPPTSSDEIPRLPQRNLSLTSPTPPLPSPGRSGPLPPPPTERPPPPVRDPPGRSGPLPPPPPINRNGSTARALPATPQLPSRSGMDSPRSGPRPPLPPDRPGAGAPPPPPPSTSVRNGFQDSSCEDEWESRFYFHPISDLPPPEPYVPTTKTYPSKVARSESRSGSNRRERGAPPLPPIPR
What is the function of this protein?
Plays a role in the reorganization of the actin cytoskeleton.  Contributes with NCK1 and GRB2 in the recruitment and activation of WASL.  Plays a role in the formation of cell ruffles (By similarity).  May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation.
What are the official names of this protein?
WAS/WASL-interacting protein family member 1, Wiskott-Aldrich syndrome protein-interacting protein, WASP-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the verprolin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Cytoplasm, cytoskeleton. Cell projection, ruffle. Note=Vesicle surfaces and along actin tails. Colocalizes with actin stress fibers. When coexpressed with WASL, no longer associated with actin filaments but accumulated in perinuclear and cortical areas like WASL.
Protein: NAPA_COLP3
Sequence: MTINRREFIKANAIAAAAAVAGVSVPAVASNLITSSDITKLKWDKAACRFCGTGCSVNVGVMDGKVVATHGDIKSPVNKGLSCVKGYFLSKIMYGKDRLTTPLLRMTNGKYDKEGEFTPISWDQAFNVMAEKANDALKKDGPEALGMFGSGQWTVQEGYAAVKLMKAGFRTNNIDPNARHCMASAVGGFMRTFGIDEPMGCYDDLEAADAFVLWGSNMAEMHPILWTRLTDRRLSAPHVKVAVLSTFEHRSFDLADNGMIFTPQTDLAILNYIANYIIQTGRVNKDFVSKHTNFRLGETDIGYGLRPEHPLEQKAKNNGKTKGSSTPIDFDEYAKFVSTYTVESVSKLSGVPEHKLKELAEMYADPKIKVTSFWTMGFNQHTRGVWANNLVYNIHLLTGKISTPGNSPFSLTGQPSACGTAREVGTFSHRLPADMVVKNPKHRAIAEKIWDLPEGTIPAKPGYHAVLQNRMLKDGKLNFYWVQCNNNMQAAANINEEAYPGYRNPKNFIVVSDPYPTVTAQAADLILPTAMWVEKEGMYGNAERRTQSWYQMVEAPEGAKSDMWQLVEFSKRFKVEDVWPEELIAKKPEVRGKTLFDVLYKDASVGKFPLSEIPEDRLNDESRDFGFYIQKGLFEEYASFGRGHAHDLAPYDRYHKERGLRWPVVNGKETKWRFKEGSDPYCKPGSDWDFYGKPDGRAVIFALPYEPAAESPDEEYDLWLSTGRVLEHWHSGSMTQRVPELYKAMPDALVYMHPDDAKKRNMRRGDLVKLISRRGEVQTRVETRGRNKPPVGLVYMPWFDASRLVNKVTLDATDPLSKETDYKKCAIKIVKV
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL14_METMJ
Sequence: MKAMQAKIPRALATGSRMVCSDNTGARLVEVVSVDRYHGVRRRQPCLGLGDVATVSVKKGTPDMRRKLEKAVVIRQKKEIRRPNGIRLSFEDNAMVLINERGEPKGTEIKGAVPREIAERFPKIASMATTIV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PYRC_SYNSC
Sequence: MSDQISIIAPDDWHVHLRDGEMLNQVVAHTARRFQRAIVMPNLRPPVTTVAAAQAYRDRIQAACPADLEFTPLMTAYLTDSIAPAELETGFREGVFAAAKLYPANATTNSAAGVTDLLQIDPVLETMARIGMPLLIHGEVTDPEIDIFDREAAFIERHLEPLRERHPELKVVLEHITTEQAVQYVSSADRHLAATITPHHLHINRNAMFAGGLRSDFYCLPVAKRECHRQALRRAATSGDPSFFLGTDTAPHERSSKESACGCAGIFNAPFALESYAQVFDQEGALEHFEAFTSLNGPAFYKLPANTHRITLQRRDHLVPELVNGLVPFHAGEILSWAVANAPDQVQL
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: SWS_DROMO
Sequence: MDVLELLRASVNGCYNTLFSDAWSQYVSKQIATTTYWYGALLAIGALFIAWFLYFKRLASLRLRDESARTLSALTAASGGDHRGLRFRKRDKMLFYGRRMLRKMKNVSGQMYSSGKGYKRRAVMRFARRILQLQRENRPLEMKTVEPPAEYLEETIDGSDRVPPDALYMLQSIRIFGHFEKPIFLKLCKHTQLLQLMAGDYLFKITDPDDSVYIVQSGMINVYICNADGSTLSLKTVRKGESVTSLLSFIDVLSGNSSYYKTVTAKAMEKSVVIRLPMQAFEEVFNENPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRIKGSNPVPVTVPGPVLSQASQASRAMASRPATSPVTRMSREEHTLSDPDPNPNASAMLFAEVHGDAPYIDLYHHQQQQSSGVSVGGTHRSSGACTPTGSGGESPDGTGNATITNIDQRLVQSSAVDSLRRELGLSEEDTSIIEPFVEVRELEPNVTLITEGNAEDVCIWFVMTGTLAVYQSNADATRAAKQDSKNDMLIHFVHPGEIVGGLAMLTGEASAYTIRARSNSRIAYIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDESSDSTYIVLSGRMRSVITHPGGKKEIVGEYGKGDLVGIVEMITETSRTTTVLAVRDSELAKLPEGLFNAIKLRYPIVVTRLISFLSHRFLGSMQTRGANASSAPVEANPVTHKYSTVALVPITDDVPITPFTYELYHSLCAIGPVLRLTSEVVRKQLGNNIFEAANEYRLTSWLAQQEDRNIITLYQCDSALSPWTQRCMRQADVVLIVGLGERSHMVGKFEREIDKLAMRTQKELVLLYPETTNARPANTLSWLNARPWVTKHHHVLCVKRIFTRKSQYRINDLYSRVLLSEPNMHSDFSRLARWLTGNSIGLVLGGGGARGAAHIGMLKAIQEAGIPIDMVGGVSIGALMGALWCSERNITTVTQKAREWSKKMTKWFLQLLDLTYPITSMFSGREFNKTIHDTFGDVSIEDLWIPYFTLTTDITASCHRIHTNGSLWRYVRSSMSLSGYMPPLCDPQDGHLLLDGGYVNNLPGHLWRYCRASMSIAGVFPPFCDYRDGHLLLDGCYTNNVPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLYKKWNPFTSPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPPIDKYKTLAFGSFDEIRDVGYVFGKNYFDNMAKAGRLGRFNQWFNKEPPKRGNHASLNEYTFIDLAQIVCKLPETYALNAVDIFSEDEDFDGYISEPTTLNMDRHRIQVPRAGNSLSFSETELDSDVEIDLELERKVDKSTQSTPPTPNKKHPSTPTSSQGNLMHLPLSMKAKDKMQILDKLEREHKRRQKSKHKRDRSMQRDSKATLHPAPMAEATTQTPSSDVDIDAKLDQLRKLQQELEQGNESEQEQEQEQEQEQGHIQEPENVTEADTKN
What is the function of this protein?
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho).  This deacylation occurs at both sn-2 and sn-1 positions of PtdCho.  Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.  Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain.  Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain (By similarity).
What are the official names of this protein?
Neuropathy target esterase sws, Swiss cheese.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Sws tethers Pka-C3 to the membrane.
Protein: UPP_BEUC1
Sequence: MRVHVADHPLVAHKLTVLRDERTDSPTFRRLTEELVTLLAYEATRDIAVEPREITTPVTTTVGVHLRSPRPMVVPILRAGLGMLEGMTRLLPTAEVGFLGLQRDEETLEAITYANRLPDDLSGRQCFVLDPMLATGGTLVASIEYLFLRGARHVTAICLLAAPEGLRTVEDAVGDRADVTIVTAAVDERLNERGYIVPGLGDAGDRLYGVV
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: DXS2_GEOMG
Sequence: MYKLLDTITGPADLKNIPREELPGLADEIRRFLIETVSQTGGHLASNLGAVELSVALHYCFDSPADKLIWDVGHQAYTHKILTGRRESFHTQRQYKGISGFPKRSESPHDAFGAGHSSTSISAGLGMAAAQDLKGSGSRAIAVIGDGSLTGGMAYEALNQAGHLKKNLIVVLNDNEMSISQNVGAFSSFVSRKMTGSDFRKLKKEMQGLLENIPAIGKDILHFARRAENSLKGFLTPGMLFEALGFDYIGPIPGHDLPQLLEVFENVKGLEGPVLVHVMTTKGKGYQPAEENPAAFHGVGPFDVATGKTTGGKPGAASYTGVFGATLVKLAEEDEKIIAITAAMPDGTGLTPFAKRFPERFFDVGIAEQHALTFAAGLAADGFRPVTAIYSTFLQRAYDQVFHDVCLQKLPVTMALDRGGLVGDDGPTHHGTFDLSYLRHLPEMTLMAPKDENELQHMLKTAIYAGRPVALRYPRGAGYGLPLDQTIQSLEIGRGELLTEGDDVAIVAIGSTVYPAQEAAKLLEARGIRATVVNARFVKPLDRELILGAARRTGCIVTVEENALQGGFGSAVLELLADEGMTDVRAKRIGIPDRFIEQGPQPQLRKDLGLDGAGIAATVEAFLTAKGQAALSLVK
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase 2, 1-deoxyxylulose-5-phosphate synthase 2, DXP synthase 2, DXPS 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PSBA_GOSHI
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAIEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ADH1G_HUMAN
Sequence: MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRTVLTF
What is the function of this protein?
Alcohol dehydrogenase.  Exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism.
What are the official names of this protein?
Alcohol dehydrogenase 1C, Alcohol dehydrogenase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE2_HPV08
Sequence: MENLSERFNVLQDQLMNIYEAAEQTLEAQIAHWLLLRKEAVLLYFARQKGITRIGYQPVPPLAVSEAKAKQAIGIMLQLQSLQKSEFADEPWTLVDTSIETYKNAPENHFKKGATPVEVIYDKQPDNANVYTMWKHIYYTDADDKWHKTTSGVNQTGIYYMQGSFRHYYVVFADDARRYSATGEWEVKINKDTVFAPVTSSTPPGSPPGQADTDTAAKTPTTSADSTSRQQRSPAKQPQQTETKGRRYGRRPSSRTRPQKEQRRSRSRHRTRSRSRSLSRVRAVGSTTVSRSRSSSLTKAVRPRSRSRSRGRATATSRRRAGRGSPRRRRSTSRSPSTNTFKRSQRGGGRRGRGRGSRGRRERSSSTSPTPTKRSRGESSRLRGVSPSEVGRSVQSVSAKHTGRLGRLLDEAIDPPVILVRGEANTLKCFRNRARVRYRGLFKYFSTTWSWVAGDSTERLGRSRMLILFTSAGQRKDFDETVKYPKGVDTSYGNLDSL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL33_THEMA
Sequence: MRVKVALKCSQCGNKNYYTTRNKDKRAKLELRKYCPKCNAHTIHTETKA
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: CLPS_CORDI
Sequence: MYGATNDVNALGVVLSSSMATPSLDEEMAVEVASSENLPWMCIVWDDPVNLMSYVTYVFQTILGYSKKRATELMMQVHTEGKAVVSSGERDKVEADVKKLHTAGLWATMQQGG
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: MCMBP_SALSA
Sequence: MPSSHDWINKPLGVVEAMFAQNNSNPEWEEKVLEYFRGQLKEKESLSWVPSLNDVPLHYLKPNSLVKFRCLVQDMFDPEFYMGVYETVDPSTKTNVLRCGKYKDVTECGVDLNSRNTVTAERQTFYCVPIPGESPWAKESYGCSSQARVVPSTSYVPSRQKRSYEEDDDDMDTQPQKQREPHTEPHGNGDSKRQETEAPSSQTTAPSDCSSHLDLNFPLPGERGPACLVKVYEGLDSFKLNDTLEIYGILSVNPVLTVLGEEKDPSSLLLNPSESMESPEEQRAHDPPASLVPRLHMLYARPLQHNNPLLPSAPTEDHSAFVSSFLVEMASVRAELLAYLTHVLLGDGLAAEYLLLHLISNVYTRRDVLPLGKFTLNLSGCPLNSYTERLYQIIQQLVPCSYRLSMSLHTMNSMRLVPKKDYVANRLVSGALQLARNTSLFLDETQLEQGQLDSSGVRNITALGNLISWQKVDYDFSYHQMEFPCNINVLVTSEGRSLLPSDCQVPLQPQVTPPNMEEYLTTIHMAQFTSQMNKFRVYLSLARTLDYSISDEVTKAVEDDFVDMRKDDPQSVTAEDLHRMLVVARLLSLSMGQTTLSRDGWMRAKHIDMLRRSRTEQQKSLNSNEP
What is the function of this protein?
Associated component of the mcm complex that acts as a regulator of DNA replication.  Binds to the MCM complex during late S phase and promotes the disassembly of the mcm complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA.  Can dissociate the mcm complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the mcm complex.  Required for sister chromatid cohesion (By similarity).
What are the official names of this protein?
Mini-chromosome maintenance complex-binding protein, MCM-BP, MCM-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MCMBP family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with chromatin.
Protein: TELL_STAHJ
Sequence: MPRNDQFNNSHPLDDYIEQQQLNNLDNNSNVSLANQNTVLDDFQQQFSDKEMQKIESISQQIKPLDNDGLLSYGSHLQENMSKFSHKMLDEVQTKDIGPVGDSLNQLMTKLKAVNPDELNPEKQSKLKRFFKRTKASINEVFSRMQSVSSQIDRITIQLDRHKNNLSKDIKLLDGLYQQNKDYFDDVNLYIAAAKRRKHEIQTNDIPKLQEHANQTGNQMDIQAVADMEQFVDRLDKRIYDLQLSRQIAIQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTLMRQRNAVSAQRAVTDTTNDLLTQNAAMLKQNAIETATENERGIVDIETLKTTQSDIIETIEQTLQIQQNGRQKRKEAEKELVGLEDELKQHLLSMKKE
What are the official names of this protein?
TelA-like protein SH1505.
What is the protein family that this protein belongs to?
Belongs to the TelA family.
Protein: YFKF_BACSU
Sequence: MSRFHFFILVLLVSISGFSQGMLLPVISIIFETNGESAAINGLHATGLYIGVLLASPFMEAPLRKLGFKPLIVMGGSIVILSLFGFIWLQSVWVWFLLRLFIGIGDHMLHFSTQTWVTSMSSKQNRGRNLSIYGLSFGLGFAAGPFMVPLVKLSPSLPFIVSGCISLFAWLFVFFLQNAYPETSPHETKSDNSFRRFYQAMLFGWVAFMPTFGYGFLETALNGSFPVYALRLGISVDAVAIILPAFAIGSIIFQFPLGILSDKYGRRNVLLVILLTGALCFFIAGVFPSPYVIGGCFFIAGMAVGSTFTLGISYMTDLLPPHLLPAGNLLCGITFSLGSILGPVAGGWYMQTFESANLFYFITLTLSSVWLALVLGKPKSWSPAETYSSSS
What are the official names of this protein?
Uncharacterized MFS-type transporter YfkF.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YRZB_BACSU
Sequence: MEHGEKNITIVDDQGNEQLCEVLFTFENEEFGKSYVLYYPIESKDDEEVEILASSFTPNEDGENGELFPIETDEEWDMIEETLNTFLADEDEE
What are the official names of this protein?
UPF0473 protein YrzB.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: CYSK_DICDI
Sequence: MFSSIYGYFNSEGDSNQQQNNNNNSNNNLKESVFHSGISNGIIETVGNTPLIRIKSLSEATGCEIYGKAEFMNPGGSPKDRVAREIILDGEKKGLLKKGSTIVEATAGSTGISLTMLGKSRGYNVQLFIPDNVSKEKVDLLEMLGAETKIVPIVGMNNANHFMHCAYQRCLGDDMAFYANQFDNLSNFNAHYNGTAKEIWEQTKGDVDGFVAAAGTGGTVAGISSYLKEVNPNIQNWLIDPPGSGLYSLVNTGVIFHPKDRLVVEKLGPRSFYEGVGVNKKTENFNKASLNGAFRGTEEEGVDMAHYLLKHDGLFLGGSSALNCVGAVKLARKLGPGKTIVTVLCDSGHRYTSRLYSKSWLNDHNFQVSDLSNLNFVK
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: SRC42_DROME
Sequence: MGNCLTTQKGEPDKPADRIKLDDPPTIGVGVGVPQIPMPSHAGQPPEQIRPVPQIPESETAGANAKIFVALYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSKKTRSEGYIPSNYVAKLKSIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKEAQAY
What is the function of this protein?
Required directly or indirectly for the phosphorylation of drpr which is necessary for the interaction of drpr with shark and subsequent glial phagocytic activity (PubMed:18432193).  Together with drpr and shark, promotes the migration of macrophages to sites of wounding as part of a signaling cascade where Scr42a detects production of hydrogen peroxide at wound sites which triggers phosphorylation of drpr and subsequent recruitment and activation of shark (PubMed:26028435).  Essential for correct eye morphogenesis (ommatidial R7 neuron formation) which requires the Ras1/MAPK signal transduction pathway (PubMed:8682295).  May be involved in the regulation of cytoskeleton organization and cell-cell contacts in developing ommatidia (PubMed:8682295).  During embryogenesis, involved in regulation of dorsal closure where it may have a role in activating the JNK pathway in leading edge cells during this process (PubMed:16831834).
What are the official names of this protein?
Tyrosine-protein kinase Src42A, Tyrosine-protein kinase Src41, Dsrc41.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Protein: HEXI2_MOUSE
Sequence: MATVNHTNCNTASPAALEEAKTSGGLRSPQIAHEPHDFGGSQLLPSGQEIQSEDEGTVPAGDGSSCNIRGSRTQSPGGCSVEAVLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPLAPYNTTQFLMNDRDLEEPNLDVLHGPSHSGSGGENEAGDSDGQGRAHGEFQQRDFSEAYERYHTESLQGRSKQELVRDYLDLERRLSQAEQETRRLRQLQGCSSRQPCQQVEELAAEVERLRTENQRLRQENEMWNREGGYCDQEKPASEGTPWPKVEAPFQTHTGQLGHREAGDR
What is the function of this protein?
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor.  Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
What are the official names of this protein?
Protein HEXIM2.
What is the protein family that this protein belongs to?
Belongs to the HEXIM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KREM1_XENLA
Sequence: MVMDIWTISLRILLFPSALVLCSDSFHSECYTVNGADYRGTQNQTSLDGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYIPEQEDGVYWKYCDIPACKMPGNLGCFRDHGNPPPLTGISETSNKQTIQTCITMCRRQRYKLAGLEAGFACFCGNNADYRKHGEMPSTDCNSVCFGDHTQPCGGDGRIILFDSLIGACGGNYSTDSAVIYSPDFPDTYGTGKACYWTIQVTDASIIRFNFTLFDIKDSRDMVELLDGYTKQVLIRFDGRNHPTHSFNISLDFVILYFFSDRINQAQGFSVVYEAFKEETIEKPNGSNNPSQTEMITQTTNLSINAARSSKILYVITTSPSRPSGHVPGWTIYALTGLLILTIIAISAKALLHISMKSARLASSSSLDSCHRGSAGEIWSIFYKPSTSISIFPKKLKGQHDDRNPLVGE
What is the function of this protein?
Receptor for Dickkopf proteins.  Cooperates with DKK1/2 proteins to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.  In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane (PubMed:17978005, PubMed:18314504).
What are the official names of this protein?
Kremen protein 1, Dickkopf receptor, Kringle-containing protein marking the eye and the nose.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RSMG_ECOUT
Sequence: MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVRDPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRVRFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGRFYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADH1_PICST
Sequence: MSVPTTQKAVVFESNGGPLLYKDIPVPTPKPNEILINVKYSGVCHTDLHAWKGDWPLDTKLPLVGGHEGAGVVVGIGSNVTGWELGDYAGIKWLNGSCLNCEFCQHSDEPNCAKADLSGYTHDGSFQQYATADAVQAARLPKGTDLAQAAPILCAGITVYKALKTAQIQPGNWVCISGAGGGLGSLAIQYAKAMGFRVIAIDGGEEKGEFVKSLGAEAYVDFTVSKDIVKDIQTATDGGPHAAINVSVSEKAIAQSCQYVRSTGTVVLVGLPAGAKVVAPVFDAVVKSISIRGSYVGNRADSAEAIDFFTRGLIKCPIKVVGLSELPKVYELMEAGKVIGRYVVDTSK
What is the function of this protein?
Converts ethanol to acetaldehyde and plays a major role in xylose fermentation.
What are the official names of this protein?
Alcohol dehydrogenase 1, ADH 2, Alcohol dehydrogenase I.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_CHLPD
Sequence: MLKIFEKVFGSKHDKDIKRIQPTIQRINEIQASFQSLSDEALREKGSLLRQQVRSRLLPLEQQKKELALKLENPDILPADADNINASLDALGEEYDKVTALALEESLPDVFALVKETCRRLKGHNYQVMGREMIWDMVPYDVQLIGGIVLHSGKITEMATGEGKTLVSTLPVFLNALTGRGVHVVTVNDYLAQRDKEWMNPVFAFHGLTVGVILNTMRPEERKRQYLCDVTYGTNNEFGFDYLRDNMAGTVEEMVQRDFYFAIVDEVDSVLIDEARTPLIISGPVPNADNSKFQEIKPWIEHLVRSQQQLVASCLVEAEKLLKTKPNDFQAGLALLRVKRGQPKNSRYIKMLSQQGIAKLVQSTENEYLKDNASQMHEVDDELYFAVDEKAGTIDLTDKGRAFLSKLSHQDTDLFLLPDVGTEIAAIEGSSSFSTAEKIKQKDAVYRLFADRSERLHNISQLLKAYSLFERDDEYVVQDGKVMIVDEFTGRILSGRRYSDGLHQAIEAKENVRIEGETQTMATITIQNFFRQYHKLAGMTGTAETEASEFYEIYKLDVVVIPTNKPVVRKDMDDLVYKTRREKYNAVVLKVEELQKKGQPVLVGTASVEVSETLSRMLRAKRIVHNVLNAKQNDREAEVVAEAGQRSAVTIATNMAGRGTDIKLGEGVRELGGLYILGSERHESRRIDRQLRGRAGRQGDPGESVFFVSLEDELMRLFGSERVISVMDKLGHEEGDVIEHSMITKSIERAQKKVEEQNFSIRKRLLEYDDVLNQQRDVIYTRRRNGLQKDRLRSDIFDLLEDYCDVVVKKYQKGADGMALEEQVLRELSVEFRPEKAEFNDDTVGGVADKLFNAAHDFYLRKEREVPEDIMRQIEKYAVLSVIDKKWRDHLREIDSLREGINLRAYGQKDPLLEYKQEAFRLFVELLREIELETLSLAFKLFPITPEEAHDIEVRQKKEALRTEKLVAQHEEAGSILSHESDVPSGTAAQQPIKADVKPGRNDLCPCGSGKKYKNCHGQQQP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.