PharMolix/UniProtQA huggingface dataset:
Protein: MUS81_MOUSE
Sequence: MAEPVRLGRKRPLPVCPNPLFVRWLTEWRDEAASRGRHTRFVFQKALRSLQRYPLPLRSGKEAKILQHFGDRLCRMLDEKLKQHLASGGDHAPSSPSGKKGASKGPPEQVQDSSMPVPTQPQAGSTSVGYWPAQNSGAREILLQLYREHLNSDGHSFLTKEELLQKCAQKTPRVVPGSSKPWPALRSLLHRNLILGTHRPARYALTPEGLELAQKLAEAEGLSTRHAGFRPEEHHGEDSAVPEALSEPGTTEGAVQQRPLELRPSEYRVLLCVDIGETRGAGHRPEMLRELQRLRVPHTVRKLHVGDFVWVAQETRPRDPERPGELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKRCGLGHRVYLVEEHGSVHNLSLPESTLLQAVTNTQVIDGFFVKRTMDIKESAGYLALLTKGLERLYQGHTLRSRPWGAPGAAESEAKPSTNPLCSLLTFSDFNAEAVKNKAQSVREVFARQLMQVRGLSGEKAAAVVDRYSTPASLLAAYDACATAKEQEMLLSTIKCGRLQRNLGPALSRTLYQLYCSHSPLS
What is the function of this protein?
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions.  May be required in mitosis for the processing of stalled or collapsed replication forks.
What are the official names of this protein?
Crossover junction endonuclease MUS81.
What is the protein family that this protein belongs to?
Belongs to the XPF family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Recruited to foci of DNA damage in S-phase cells.
Protein: TRIB3_HUMAN
Sequence: MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
What is the function of this protein?
Inactive protein kinase which acts as a regulator of the integrated stress response (ISR), a process for adaptation to various stress (PubMed:15781252, PubMed:15775988).  Inhibits the transcriptional activity of DDIT3/CHOP and is involved in DDIT3/CHOP-dependent cell death during ER stress (PubMed:15781252, PubMed:15775988).  May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells (PubMed:15781252, PubMed:15775988).  Acts as a negative feedback regulator of the ATF4-dependent transcription during the ISR: while TRIB3 expression is promoted by ATF4, TRIB3 protein interacts with ATF4 and inhibits ATF4 transcription activity (By similarity).  Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation (By similarity).  May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1 (By similarity).  Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity (PubMed:12736262).  Interacts with MAPK kinases and regulates activation of MAP kinases (PubMed:15299019).  Can inhibit APOBEC3A editing of nuclear DNA (PubMed:22977230).
What are the official names of this protein?
Tribbles homolog 3, TRB-3, Neuronal cell death-inducible putative kinase, SINK, p65-interacting inhibitor of NF-kappa-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NTA_CHIGU
Sequence: LCSREGEFCYKLRKCCAGFYCKAFVLHCYRN
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
Jingzhaotoxin F7-15.33, Peptide F7-15.33.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP_MESH2
Sequence: MINVNEFRPGITFEFENEIYVVISAQHSKQGRGQANVKAKVKNLRTGAITIKTFSGGERVEKAHIEKISMSFLYNDGVSIVLMDDSTYEQVAIENTKITWELNFLTEGIKVKLRKFNNEILDIELPAKIELKITSTFDAVRGNTTTNPTKRATLETGYEIDVPLFIKEGESVIVSTEDGKYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1A_META3
Sequence: MQKKPMAPQQPTRVRTPREENNEILGIIEQMLGASRVRVRCMDGHTRMGRIPGKLKRKIWVREGDIVIVVPWEVQSDQKCDIIWRYTKGQVSWLSKKGYLKQAYD
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: PGA39_CANAL
Sequence: MKATTFTLLLSIATAINAAAFEDSRLKALFARDAEISFGATLSAEISHGFGHHHGHTADLSSEIGGGSSSSSVSESTVEELSTTTTTESVSASVSASVSASVSASVSVSSSAEETSTEATESAETTDSFETTDSAETTDIVETTDSVDTNTTDISTTDETTEETTDATDSVETTFESVSNTEDLSSSSSSIITDSSESTIEETPLITDTSVPSSLSEEYSTSGSSSEWIHTTTAATSHNSSNSNSNHSNVSNTTTSANFAIQYGTDYGVAVVAAIVGALLI
What are the official names of this protein?
Predicted GPI-anchored protein 39.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: RM16_ACACA
Sequence: MRFKKYFKIKYKNNNVYEHDLIHFGDFGLKSLGNCNLTSEQLTASLKAIKRVIKKKNFLIIKALPFWMLTRKPRDVRMGRGKGSPAVKVYPLKAGKIIFEFKNVNETLLLRALKSSSLRLPVPTKVVKKYDKRTDCIKSSW
What are the official names of this protein?
60S ribosomal protein L16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRMB_MESH2
Sequence: MRLRNIPDALERIQNQNLLVKTPWNIDDSWIIEIGMGKGKMISQLAFDNPNKNFLGVEKYPSAAVKSIKYVKKYNLSNFFILISDAKDLLDQIKGKASTIWLTFPDPWPKNRHYKRRLTYKDFLKIYANLLVKDGILKLKTDNLKFFEFSIESLKENGWKITYQTNDLHNSLVNSSNIKTTYEEKWVNLNYKIHYLEAIFI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: CPB3_CAERE
Sequence: MSQEEVPGEIPGDIAIEKAENTVQDDVEAKNTSETKKTIPPMLNVEKVDVAAVGEKSPAPVSVYDLFKKYQKPDVKSDSEDMNIGFDQLTTDEKNGFLRKLQMLTVGNKKTLKVPGESTPSPASRLLKKFVPSRRPSTENKSCESPSRFSLFGKSNKKAPELERPMNGGQPRKKSARRLNFGKEIEERTETDFQNNRVVAAMTREYEKIVTLKGVPVPINKPPRQQGPRGSLETPTDSPAKTETSSISKSYGSDYQSSRDRYTSINEDSLTKKRISTPNRGQGLSNRDNATWHGELPPRDYTSPTFSRKIFVGGVPWDITEAALKDSFGEFGSCAVEWPGHEARYRNAQSNTASLNLRNQSKYTGQAATGYVYMIFEDERAVASLLHECSQEIGGAGEWYFKIRAQRSKSTEIRQVQIIPWVTSDSMFCEDESLLEVGIEPKRTVFVGALHGMMTAQVLHSIMEDCFGSVECVQLDTDKFKYPIGSGRVTFREHGAYFKAIEMGYLHVHTSKFRKRVQIDPFLESTNCMVCTTELAHCFCRNRNCFKYYCHTCWAVDHGHGHDGEVHVPVIVPSSASKAFSGPNRRSHLSSNSPSKPASLMSSSNSQVAHMVSPAYPVLVGAPAQNLSALYGYIQNSQQMMITPAAVYEPPMTPSPNEMKRRSFPEFQPQPTVFFNSTPMMTPQKGVPCSDGSAVPAYYANSAAFLTPPSSYYNSPSHSTSSNLSPQQPQQYYGANLYYGYMPQMSYDGGPNQSAMHLPHTPNYQQ
What is the function of this protein?
Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs.
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 3.
Protein: CF141_HUMAN
Sequence: MNDPFARMETRGPQGAANPMDSSRSLGDLGPFPREVGRGAPLAPGARNPATAGASRSQGGGHEDRTADRALGPRAGEELDRESWVREKVLFLLHPERWLGTRGDPAREEVAGAEDLPHAGGEDHGEEPNYPSVFQRQKRISGRRVAPPRDAADPPKYVLVRVEDYQVTQEVLQTSWAKGRMTTRTEEHFVTALTFRSSREGQPGERWGPAESRALQARTGASRVHAAGRRVSPSPGTWLEEIKL
What are the official names of this protein?
Uncharacterized protein C6orf141.
Protein: DNAL4_MOUSE
Sequence: MGETEGKKEEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS
What is the function of this protein?
Force generating protein of respiratory cilia.  Produces force towards the minus ends of microtubules.  Dynein has ATPase activity (By similarity).
What are the official names of this protein?
Dynein axonemal light chain 4.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: RL1_SALAR
Sequence: MAKLTKRMRVIREKVDATKQYDINEAISLLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAEQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSQAKGVYIKKVSISTTMGAGVAVDQAGLSASAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ZN264_HUMAN
Sequence: MAAAVLTDRAQVSVTFDDVAVTFTKEEWGQLDLAQRTLYQEVMLENCGLLVSLGCPVPKAELICHLEHGQEPWTRKEDLSQDTCPGDKGKPKTTEPTTCEPALSEGISLQGQVTQGNSVDSQLGQAEDQDGLSEMQEGHFRPGIDPQEKSPGKMSPECDGLGTADGVCSRIGQEQVSPGDRVRSHNSCESGKDPMIQEEENNFKCSECGKVFNKKHLLAGHEKIHSGVKPYECTECGKTFIKSTHLLQHHMIHTGERPYECMECGKAFNRKSYLTQHQRIHSGEKPYKCNECGKAFTHRSNFVLHNRRHTGEKSFVCTECGQVFRHRPGFLRHYVVHSGENPYECLECGKVFKHRSYLMWHQQTHTGEKPYECSECGKVFLESAALIHHYVIHTGEKPFECLECGKAFNHRSYLKRHQRIHTGEKPFVCSECGKAFTHCSTFILHKRAHTGEKPFECKECGKAFSNRKDLIRHFSIHTGEKPYECVECGKAFTRMSGLTRHKRIHSGEKPYECVECGKSFCWSTNLIRHAIIHTGEKPYKCSECGKAFSRSSSLTQHQRMHTGKNPISVTDVGRPFTSGQTSVTLRELLLGKDFLNVTTEANILPEETSSSASDQPYQRETPQVSSL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 264.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRIS_HALWD
Sequence: MEDRTRTYLKGRFGDYYARARMDTPPAANRREWGHIPWSAGSTTMVRHQSLLELGTLDDFLHRTAPKHVYFSAARFNDPGATTMDQKDWQSADLIFDLDADHLPGVNPDTTSYADMLTACKTELQTLLEFIDDDFNFDETQVVFSGGRGYHVHVRDEQVRSLDSAARREIVDYIRAIDLNIETLIETQSNHGTTQRILKHRGGWGQRIHKRLVELIETLQASDDTEALERLQSFEGIGTGRAETILGQIQNNPEAIHAGNLEAGGAGIRILADALAQTAFEAETAPIDEPVTTDTNRLIRLPGSLHGGSGLLVTPLDREEIPSFHPLEHAIADRFRGRDIQIRITDSGVTTFDGETFDITEGNKTVEECLGIFLMARGRAEKVTE
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: NADE_TROWT
Sequence: MCCDISKTLCVKPFIDPEEEISHRVSFLADYLRHSRASGYVLGISGGQDSALAGRLCQIAVESVRSIGFDATLWAIRLPYGQQFDESDAQTAMQFISPDEELSFDIRSATDNLCVDLNRSLGSKISDFNRGNIKARLRMVVQYAVAAHHDALVVGTDHAAEAVTGFFTKFGDGAADILPLYGLTKGQGRALLKALGACDSIIEKVPTADLLDDLPCLPDETELGLQYRDIDAFLEGKPVSEDITMAITERYKSTLHKRMPPITPHSTWWRK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: OSPB_BORBU
Sequence: MRLLIGFALALALIGCAQKGAESIGSQKENDLNLEDSSKKSHQNAKQDLPAVTEDSVSLFNGNKIFVSKEKNSSGKYDLRATIDQVELKGTSDKNNGSGTLEGSKPDKSKVKLTVSADLNTVTLEAFDASNQKISSKVTKKQGSITEETLKANKLDSKKLTRSNGTTLEYSQITDADNATKAVETLKNSIKLEGSLVGGKTTVEIKEGTVTLKREIEKDGKVKVFLNDTAGSNKKTGKWEDSTSTLTISADSKKTKDLVFLTDGTITVQQYNTAGTSLEGSASEIKNLSELKNALK
What are the official names of this protein?
Outer surface protein B.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: KAX2A_CENEL
Sequence: IFINVKCSLPQQCLRPCKDRFGQHAGGKCINGKCKCYP
What is the function of this protein?
Weakly blocks Kv1. 3/KCNA3 voltage-gated potassium channels (Kd is estimated to be 366 nM).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 2.10, Toxin Ce3.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PURK_ALIF1
Sequence: MNVLILGSGQLARMMSLASAPLNIDVIAYDVNSQQIVHPLTQQPIDLSLEQAIKQVDVITAEFEHIPHHILDICSVSGKFQPTPDAIKAGGDRRLEKKLLDNAHVANAKYHNINTKQDFLNAIDTVGIPMVLKSALGGYDGKGQWRLKDVSQVDSIWEEMDELIKSSPNQAIVAEQFIPFNREVSLIGARNKNGQMVTYPLTENVHVDGVLALSTALEGTSNLQQQADEMFTAIADELNYIGVLAIEFFDVDGTLLVNEIAPRVHNSGHWTQQGTDICQFEMHIRAVCNLPLTGNQLLRSTAMINILGEDSLPDEILTMPNCHIHWYGKEKRAGRKMGHINVCADSPEMLQKELSKLANILDKQAFKALS
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide synthase, N5-CAIR synthase, 5-(carboxyamino)imidazole ribonucleotide synthetase.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: SYY_HAMD5
Sequence: MISNNLIEQLEQRGLIAQVTDKTRLSERLYQGQISLYCGFDPTADSLHLGHLVPLLCLKRFQLVGHKPIILVGGATGLIGDPSFKAGERKLNDIDTVHQWVNKIREQVEPFLDFDCGNHSATIENNHNWFSHINVLTFLRDIGKHFSVNQMMNKEAVKQRLSRTDSGISFTEFSYNLLQSYDFAYLNKNHKVELQIGGSDQWGNITSGIDLTHRLNRRSVYGLTVPLITKADGSKFGKTEGNTIWLDAKKTSPYQFYQFWLNTADADVYRFLKLFTFIDLNAIDALEEQDKKNDKAPQAQYVLANEITEMVHGKEGLSAAQRITASLFTGNPHDMREEDFSQLAQDGIPIVRLETDAELQKALVSAQLAPSRSQARTLIQSSSISVNGKKQLKPEYIFTSEDRLLDRYTLLRRGKKYYCLIIWQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_LEPBJ
Sequence: MNKGKIKQIIGSVLDIEFENGELPEIYNALEIEATVSGKREILIAEVQTHIGGKAIRAIALSSTDGLIRGQEVTNTGKPISVPVGDATLGRIFNVLGKTIDEGPAITVKETRPIHRPAPAFDELTSKTEVFETGIKVIDLLAPYIKGGKTGLFGGAGVGKTVLIQELINNIAKQHGGFSVFAGVGERTREGNDLWREMKESGVIDKTVLCYGQMNEPPGARLRVALSALTMAEHFRDSIGTDVLLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPANAFAHLDATTVLSRAISDKGIYPAVDPLDSTSRVMNAQVLGEEHYTVAREVQRILQRYKDLQDIIAILGMDELSEDDKVLVARARKIEKFLSQPFHVAEVFTGAPGKYVKLADTVRSFKEVISGNYDHLPEQAFYMVGSIDDAIEKAKGYKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRF_ECOL6
Sequence: MTLTASSSSRAVTNSPVVVALDYHNRDAAMAFVDKIDPRDCRLKVGKEMFTLFGPQFVSELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASGGARMMAAAREALVPFGKDAPLLIAVTVLTSMEASDLADLGVTLSPADYAERLAALTQKCGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSDAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKAINASLQRSA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RNSE_THET8
Sequence: MRIVPFGAAREVTGSAHLLLAGGRRVLLDCGMFQGKEEARNHAPFGFDPKEVDAVLLTHAHLDHVGRLPKLFREGYRGPVYATRATVLLMEIVLEDALKVMDEPFFGPEDVEEALGHLRPLEYGEWLRLGALSLAFGQAGHLPGSAFVVAQGEGRTLVYSGDLGNREKDVLPDPSLPPLADLVLAEGTYGDRPHRPYRETVREFLEILEKTLSQGGKVLIPTFAVERAQEILYVLYTHGHRLPRAPIYLDSPMAGRVLSLYPRLVRYFSEEVQAHFLQGKNPFRPAGLEVVEHTEASKALNRAPGPMVVLAGSGMLAGGRILHHLKHGLSDPRNALVFVGYQPQGGLGAEIIARPPAVRILGEEVPLRASVHTLGGFSGHAGQDELLDWLQGEPRVVLVHGEEEKLLALGKLLALRGQEVSLARFGEGVPV
What is the function of this protein?
Has endoribonuclease activity towards 23S and 16S rRNA (in vitro).
What are the official names of this protein?
Ribonuclease TTHA0252.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_PARL1
Sequence: MTSSKSHPEAADIQRVRRALLSVSDKTGLIDFARALHGAGVELISTGGTAKAIKDAALPVKDVADLTGFPEMMDGRVKTLHPKVHGGLLAVRDDAEHAAAMKEHGIAGIDLLCVNLYPFEATVAKGAAYDECVENIDIGGPAMIRAAAKNHAYVGVIVDGADYAAVIEEITGKGGTSLVLRKRLAQKAYARTAAYDAAISNWFANAIGETAPDYRAFGGSLKQTLRYGENPHQVASFYVTGENRPGVSNAEQLQGKELSYNNINDTDAAFELVGEFDPKLAPAIAIIKHANPCGVATGATLADAYRKALACDPVSAFGGIIAANRPLDGETAEEIARIFTEVIIAPEADEDARRIIGAKKNLRLLITHGLPDPATAGLFYKSVAGGLLVQSRDNGRVDTLDLKVVTKRAPTAQEMEDLKFAFRVCKHVKSNAIIYVKNGATVGIGAGQMSRVDSARIAARKAQDAAEAAGEKTPATIGSVVASDAFFPFADGLLSAAEAGATAVIQPGGSVRDDEVIAAADEKGLAMVMTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: YHDJ_BACSU
Sequence: MIHMKQLTSKEEWAESYPIMSELRTELDIETYLQRLEACVQKESYMLFALYENTAIRALCGALPRVSIHKGEHLWIADLVTTAPCRSKGYGKMLLDYASDWARKAGLGFVSLSSGLQRKDAHRFYTDKMGFTIESYLFRKPV
What are the official names of this protein?
Uncharacterized N-acetyltransferase YhdJ.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: CBPA_SALG2
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQLWQHRNDPQFNRQFQQHEGQPYNAEDFDDIFSSIFGQHGRHSHHRHAARGHDIEIEVAVFLEETLEEHQRTISYSVPVYNAFGLVEREIPKTLNVKIPAGVSNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVNQDLEVVLPLAPWEAALGAKVSVPTLKERILLTIPPGSQAGQRLRIKGKGLASKKHTGDLYAIIKIVMPPKPDEKTAALWQQLADAQSSFDPRQQWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PAP5_PARMA
Sequence: GFFALIPKIISSPLFKTLLSAVGSALSSSGDQE
What is the function of this protein?
Exhibits unusual shark repellent and surfactant properties.  Forms voltage-dependent, ion-permeable channels in membranes.  At high concentration causes cell membrane lysis.
What are the official names of this protein?
Pardaxin P-5, Pardaxin P5, Pardaxin Pa5.
What is the protein family that this protein belongs to?
Belongs to the pardaxin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: MSBA1_COLP3
Sequence: MASSPKTNALSSSDSANATTWQNFKRLVSYAKPYKLGFVAAIIGMLGYAAIDVYFLSQLKPLVDEGLSGANANFMKWAPLFIIVAFTVRGIAHFIANYCLAWVGNNVVADLRQKLFEHIMSMPVAFHDQTSTGSLISKITFDTEQVLNSVSKSILTIVQQSAFIIGLLGLMFYYSWQLSLIFLLITPIIAVIVSVVSKRFRKVSKNIQGAMGEVTTAAEQTFNGHKVVLTFGGQQREFSRFAKINKHNRQQRMKMRATKSASVPIIQVIASFALAFVFYAITSDSLRDSISPGTFVSIITYMTMLLRPLKMLTNVNSEFQQGMAACTSIFSILDHEKEKDNGDKQLERASGTLSFKHVDFSYKNTNTMTTSDKEQDTKLALNDITFDLAPGETLALVGRSGSGKSTASSLLLRFYDATRGEILIDDTNIEQFQLKDLRKQFSYVSQQVVLFNDTLANNIAYGKPEATEAEIIEAAKSAHVMEFAEHMEQGLETNIGENGALLSGGQRQRVAIARALLCDTPFLILDEATSALDTESERHIQDALQTLQQNRTSIVIAHRLSTIENADKIIVMEQGKIVEQGNHQSLLAKQGAYAQLHSFQFE
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase 1, Lipid A export ATP-binding/permease protein MsbA 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCN6_SCHPO
Sequence: MVLISNTLHCADAYSSADSKHVPLTLSTRRINLQSFQSISARNCGSDARVLDFVKSIDNDNSWKRRNLDSKRNIGSRKKNRFLNDLHILKQAADDPDEVVYKDLFTHRPAFGFLTVGDEFYKDGVNNISSLLTSSSNQRFNDNHHKSIVKRIRHEIKCYNSLQLVLLLDECLNNIMNEKLYAYDHDHSPAIYASESFNIKAEIDTSSFLETQRSYRIYMLIDCPSNPKATAFARYWMHLICSYYGIYTTSTQILSNKIMTLGVSKKRKHLSFKTLSELLNHDELTNINR
What are the official names of this protein?
Uncharacterized protein C320.06.
Protein: AROB_PSYA2
Sequence: MATPLFHADLTVHTQSHDYPIVITENTATENAIAEESSMASQVAPYIAGQQVLIVTNETIAPLYLKALKQPLEVQFTVQVCVLPDGEQYKNQSSINQIYDVLMAAHFNRDVTLIALGGGVIGDMTGFSAASFMRGVNFIQIPTTLLSQVDSSVGGKTGINHPQGKNMIGAFWQPQMVLADMSTLKTLPARELSAGLAEVIKYALIMDADFLTWLEHNLPAMMALNLVILGEAVKRCCEYKADIVAQDERESGVRALLNFGHTFGHVIETHEGYGNWLHGEAVAAGMVQAAELSQKIGWLTSDEVARVKRVLLLANLPITPPPIAVQTALNLMGHDKKVKHGQIRLILLKSLGEAVLTNDFDPDLLTDVLSQHAIHAKDDAQATTATVL
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y272_SHESW
Sequence: MTKKIEVAQIRVLFLGIWRFLQHLRLRLVEDQINIRAGHLAYVTLLSLVPLVAVTMSMLSAFPVFKGIRGQIEAFVYENFLPAAGDTVQIYINEFVGNASKGTAVGIAALVVVAIMLISAIDKSLNNIWRTKEKRSVVVAFSMYWMVITLGPVLVGASLVATSYVVSLKLFEDDTFSGVVPLFIERLPMLFSVAAFLLLYMVVPNQKVKFLHALLGALVAALLFELGKKAFALYVTQFPSYEAIYGALATIPILFVWVYLSWMIVLLGAEITAAMPEYLDYESSFDKDEASTKT
What are the official names of this protein?
UPF0761 membrane protein Sputw3181_0272.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.