PharMolix/UniProtQA huggingface dataset:
Protein: RPOC2_SACOF
Sequence: MAERANLVFHNKEIDGTAIKRLISRLIDHFGMGYTSHILDQIKTLGFHQATTTSISLGIEDLLTIPSKGWLVQDAEQQSFLLEKHYYYGAVHAVEKLRQSVEIWYATSEYLKQEMNSNFRITDPSNPVYLMSFSGARGNASQVHQLVGMRGLMADPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTADAGYLTRRLVEVVQHIIVRRRDCGTIQGISVSPQNGMTEKLFVQTLIGRVLADDIYIGSRCIASRNQDIGIGLVNRFITAFRAQPFRAQPIYIRTPFTCRSTSWICQLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTADLIRSPSNGKIQFNEDLVHPTRTRHGQPAFLCYIDLHVTIQSQDILHSVNIPLKSLILVQNDQYVESEQVIAEIRAGMSTLHFKEKVQKHIYSESDGEMHWSTDVYHAPEYQYGNLRRLPKTSHLWILSVSMCRSSIASFSLHKDQDQMNTYSFSVDGRYIFDFSMANDQVSHRLLDTFGKKDREILDYLTPDRIVSNGHWNCFYPSILQDNSDLLAKKRRNRFVVPLQYHQEQEKERISCLGISMEIPFMGVLRRNTIFAYFDDPRYRKDKRGSGIVKFRYRTLEEEYRTQEEEYRTREEEYRTREEEYRTREEDSEDEYESPENKYRTREGEGEYEILEDEYRTLEDEYETLEDEYGILEDEYRTLEKDSEEEYGSLENKYRTREGEGEYEILEEDSEEEYGSSEDGSEKEYGTLEEDSEEDSEEDSEDEYGSPEENSILKKEGFIEHRGTKEFSLKYQKEVDRFFFILQELHILPRSSSLKVLDNSIIGVDTQLTKNTRSRLGGLVRVKRKKSHTELKIFSGDIHFPEEADKILGGSLIPPEREKKDSKESKKRKNWVYVQRKKILKSKEKYFVSVRPAVAYEMDEGRNLATLFPQDLLQEEDNLQLRLVNFISHENSKLTQRIYHTNSQFVRTCLVVNWEQEEKEGARASLVEVRTNDLIRDFLRIELVKSTISYTRRRYDRTSVGLIPNNRLDRNNTNSFYSKAKIQSLSQHQEVIGTLLNRNKEYPSLMILLASNCSRIGLFKNSKYPNAVKESNPRIPIRDIFGLLGVIVPSISNFSSSYYLLTHNQILLKKYLFLDNLKQTFQVLQGLKYSLIDENKRISNFDSNIMLEPFHLNWHFLHHDSWEETLAIIHLGQFICENLCLFKSHIKKSGQIFIVNMDSFVLRAAKPYLATIGATVHGHYGKILYKGDRLVTFIYEKSRSSDITQGLPKVEQIFEARSIDSLSPNLERRIEDWNERIPRILGVPWGFLIGAELTIAQSRISLVNKIQKVYRSQGVQIHNRHIEIIIRQVTSKVRVSEDGMSNVFLPGELIGLLRAERAGRALDESIYYRAILLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGIIPVGTGFQKFVHRSPQDKNLYFEIQKKNLFASEMRDILFLHTELVSSDSDVTNNFYETSETPFTPIYTI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSAL_HUMAN
Sequence: MWLAAAAPSLARRLLFLGPPPPPLLLLVFSRSSRRRLHSLGLAAMPEKRPFERLPADVSPINCSLCLKPDLLDFTFEGKLEAAAQVRQATNQIVMNCADIDIITASYAPEGDEEIHATGFNYQNEDEKVTLSFPSTLQTGTGTLKIDFVGELNDKMKGFYRSKYTTPSGEVRYAAVTQFEATDARRAFPCWDERAIKATFDISLVVPKDRVALSNMNVIDRKPYPDDENLVEVKFARTPVTSTYLVAFVVGEYDFVETRSKDGVCVCVYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPYPLPKIDLIAIADFAAGAMENWDLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQWFGNLVTMEWWTHLRLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSHPIEVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDKDFKKGMNMYLTKFQQKNAAAGNL
What is the function of this protein?
Aminopeptidase with broad substrate specificity to several peptides.
What are the official names of this protein?
Puromycin-sensitive aminopeptidase-like protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
Protein: TX116_LYCSI
Sequence: MMKVLVVIALLVTLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1b, Toxin-like structure LSTX-A16.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PHF3_HUMAN
Sequence: MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSASNQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEENSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQVKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKCNNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSISGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSLVGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSNLEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSYLESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQNFHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKSHAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDKLKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEILDPDTLENQATVEFHSGDKTMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNSSDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQEMKKKKVEKGVLNVHPAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLEKPEGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVVVGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVESTFLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATDKIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPPDKKSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEPPKPLRFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLNEQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISAGSLTSLSLRGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNVGKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCRNGEKHMLPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQEDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRPQQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR
What are the official names of this protein?
PHD finger protein 3.
Protein: MURA_RHIME
Sequence: MDRIRIVGGNELHGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGADISVNGRRERQGESYARTVHFTSRNIVSTTAPYELVSKMRASFWVIGPLLAREGKARVSLPGGCAIGTRPVDLFIEGLAALGANIEIDGGYVNATAPAGGLIGARYVFPKVSVGATHVLMMAATLANGTTVLGNAAREPEVVDLAKCLNAMGAKISGQGTSTVTIEGVRSLSGARHRVLPDRIETGTYAMAVAMAGGDVILEDTEASLLDTALEAIRRAGAQISETNSGIRIVRNGAGIKPVDIVTDPFPGFPTDLQAQFMGLMTRSSGVSHITETIFENRFMHVQELARLGAKISLSGQTAKVEGVSRLKGAPVMATDLRASVSLVIAGLAAEGETMVSRVYHLDRGFERLEEKLTRCGAHVERVSD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_ECOLC
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_ECOHS
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NUOA_CHLTE
Sequence: MDQTLSGFGTVFVFLVLGIVFVVGGYLTARMLRPSRPNPEKNSTYECGEHAVGSAWVKFNIRFYVVALIFIIFDVEVVFLYPWATVFKQLGAFALVEVLIFVGILVLGLVYAWVKGDLDWVRPTPNIPKMPEMPVRRSGKANG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RK16_OENAR
Sequence: MLSPKRTRFRKQHRGRMRGISYRGNRICFGKYALQALEPAWITSRQIEAGRRAMTRNVRRGGKTWVRIFPDKPVTLRAAETRMGSGKGNPEYWVAVVKPGRILYEMGGVAENIARKAISIAASKMPIRTQFIISG
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NIFK_METMI
Sequence: MSELNVITKERTAVINPIVTCQPLGAMYAVSGIERGMPLVHGSQGCSTFVRYGFARHFREPADIAVTSLHEDAAVFGGRKNLISGLGNLAARFKPDVMGVVTTCSSEIIGDDVAGFIKTAKVEIAKKMGEEAANKIKIVQINTPSFVEHQFKGYDNAIKAIVDTLAEPKDEENGKLIIIPGIVNPGDIREIKHMLSLMGVEGILLTDTSDPFDSPLRPSKADKNPYYQKGGTPLADLQDCANSLGTISLANYANSAPASLEKKYNMPSKVSEAPIGIQNTDSFIRTVKKFTGNDVTDEILDERGIVIDAMADVASRYLFGRKVAIYGDPSITVGMARFVAELGMIPKVVCTGVKNEYFVNDLKKVAKESDEDIDALFGQDLRALDVYLKENPVDLMIGSSDGRLMAKDLGIPLYRVGYPVYDRVGYQRRPIIGYNGALNLVDGITNTILDKYYETQDWKLQQ
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein beta chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: PKS19_PHANO
Sequence: MTRAKVIYFSGEIPQGDPEGDQRNLFRKLHLLSKERDYPILASFLETVTWAMKEEHRRLVRAQRDLLPTFESILDLTDHVVELRKTSLGGAIERVLVLAFQLGSFIAYHEAHPLEYNFQASDTFLIARGPGMLSAAAVALCPSLPMISSISADITRVAFRFGLVVDQVCRSLEVSPDEINSAGAWIYCVYGVDPQKAHEAVTRFNAEKAYAETSMASVFNDDGKSVSIGGPPSTLKTLFTECDFFKRTKNVPMKKVQGMWHTGKVYGTEHVHQIIPKIHQKHQLYLPLFSPVKGQPLEAASATDLLEQIMEEMLTQRIRWDRTIQNVTERLKQASPESTQLIAIQPSQYVESLIGQWRADMPTTTHTTEDMMSAVMDLPLGNSRAKDAKSSKIAVVGMACRFPGGADNAEKFWELLAQGRDVHSPIPSDRFNIETHVDPAGKVPNTSKTPYGCFVDNPGLFDAMFFGMSPREAEQTDPMQRLALVTAYEALEHSGYVHGRGIHARRVGTFYGQASDDYREVNSGQDVGTYFIPGGCRAFGPGRINYFFKFWGPSFSVDTACSSSLAAIQAACTSLWSGDVDMAITGGMNIITNSDVYAGLSNGHFLSPTGGCKTWDEGADGYCRADGVGSVVLKRLEDAEADNDNILGVVLAAATDHSAEAVSITHPHDVAQAHLYNQVARRAGIDPLAVGYVEMHGTGTQAGDSNEMKSVTNVFAPSTGHIRDRDSPLHIGTVKSNMGHGEAAAGIMAFVKTMLVFQKGIIPPHIGIKTRFNPALPEDLAKRNVVIPVTAAIWVRNSDRKRLAMVNNFGAAGGNTSIIIEEAAPRPRTSEDVRKAQVITVSAKTANSLQENLKALVDYIEARSELSVADLAYTLSARRNHYNYRVSVLATSTAEAASLLRPHIKTSLSQTPHSGKQVPIAFAFTGQGTFYIGIGAQLYRDSHEFRKHIDQLDSLVRRQNFASFLPVVSGNVQPEDVSIVTMNLAIVCVEIALARLWESFGIKPSMVIGHSLGEYAALAVAGVLSDSAAIFLVGTRARLLTSKCTSRTHGMLSVRASAADIKHAGGDIPFEVSCINGPNETVLGGTLSNMEALSATLAAAGYRTFKLDLPHAYHTYQMDTIVDELVKQTETVVCKKTTIPIISPRFSRVMTSEDSIDVSYLIGATRETVDFAGALDDAWQSGLVNESTIWLEMGHHPTCSGFISRTLSSTRMALPSLQRDTDNWLTLAKTLCSLYSAGIPIDWNEYHRPFEQALRLIDAPTYAWTNKNYWIQYRGDWNLTKGRAMPKLDPTTTVVPVSKRFQTSSIHRLISEQYTDGKAILSAESSITDPSLQGVVDGHAMNGYGVASSFLHAEMAFTLAKRVSDKSFASAVSFGINVADFEYHEPVVKLINTSEPQPILVSAEADLEKMEVHVKWFNPAKEIWYCHATVFYEDPSSWLSTWSRSTKLITSRIDALNDMAVTGKASKLTTDLAYSLFGKLVGYSKLYQTMQSVILNEDEAMAEVQFPEDTGGSWTVPPHFIDGLISLSGFILNGGTHFDNTNNFFITPSWKSMRFARPLTPGGRYTAYVRMVPSDNHSFVGDVYVLQGSEIVGVVEAILFLQWPRVMLNRFFRPADVTAKPAAKVPGKSEPSTRPHFKPHHVSRHKPTLTPRSPDEGSENSDSSGVIISRPGGYSSSDQDMEELPSPPAGMNDDMEKALALVAEELAVDIGLLTDDALIADLGLDSLMSLVMSQRLREELGLEIRDAFFLEITTIQDLKALLR
What is the function of this protein?
Non-reducing polyketide synthase that mediates the biosynthesis of alternariol (AOH), a micotoxin that seems not to be involved in virulence and oxidative stress tolerance (PubMed:26025896).  PKS19 alone is sufficient for AOH synthesis which is initiated by priming with acetyl-CoA, followed by sequential condensations of 6 malonyl-CoA units (PubMed:26025896).
What are the official names of this protein?
Non-reducing polyketide synthase PKS19, NR-PKS PKS19, Alternariol synthase, AOH synthase.
Protein: KGUA_PSEF5
Sequence: MTHSTGTLYIISAPSGAGKSSLVKALTDAKPEIRVSVSHTTRAMRPGEVDGVNYHFVSRETFVKMGEHGDFLERAEVFGNLYGTSQSHLQQTLDAGHDLILEIDWQGAEQVRKLMPQARSIFILPPSLQALHQRLTNRGQDSDEVIDGRMREAVSEMSHYVDYDYLIINDDFAHALGDLKAIFRANQLQQKRQQQRFGKLLAELLG
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_SORC5
Sequence: MRLLFGDAAASARRPEEYEARYPRRALPKGAMVTRYAPSPTGFMHIGGIFVSLINKRLSLQSEGVFYLRLEDTDVKRAIPGALDTIVDSLARFDLSPQEGVLRAPAKDGDASSRGEFVQQGSYGPYIQTERVEIYRDYAIDLIRRGFAYPCFCTVEELDAIRQEQMALTVKPGVHGRWAKWRDAPLARVKEALAGGTPFVLRLRAPDDVSGRVEWKDGVKGVISMPVNDLDTILLKSDGIPTYHFAHAIDDHLMRTTHVIRGDEWISSMPLHLQLFRTLGFRPVEYAHVPPIQKLDRVEEVDPETGETKVSDARRKLSKRKDPEANIAYYREIGVPETGTIEYLLNIANSAFEDWRKANPDKPYSAFPLKLNKLAPGGALSDMVKLKSVSQAVVSRMSAEDVYAQGLDWAREHDKELAALMERDPEYTKRALGIERGGKKSNKRITTWPDLRPQLFFFYDELYDRVDALDFPENVPEGDRQPLLRQMLDTFDPADSKEAWFEKIRQIAVASGYAGEVKQYKASPESWKGHVGDVSMLLRVAVCGTRNSPDLTEVMAVLGEPRVRARIARFL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHA2_STAA3
Sequence: MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
What is the function of this protein?
May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer.
What are the official names of this protein?
Alanine dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
Protein: Y440_METJA
Sequence: MYYKLVLSHYSKTSTLINITLIKHLINILRERMIQEIKNFIYKYYIEPAEKGTGYNIVQEITYGIILALALYLFYKALRKLNINIDEKFAIPGIVFTVLIALMRALVDCGYIERSFLTITPGIVFLIGGFFILTILTTGLVFKEKYYKASAVIGLILLLYFLFVFLQHITHLEAILYVGILVGIFYYLVKFLDKTLKLNIIQSKIDDYVVIGQLIDASATTIGIGVYGYWEQHPIPRFLMETFGVYAFIPFKLLIILLALYILNKEVEDENIKNIIKLCIMALGLAPGLRDLFRTVMGV
What are the official names of this protein?
Uncharacterized protein MJ0440.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PEX10_DICDI
Sequence: MSNVQSQSNSHHPVHNIVNRSPTSRSEQQIRSIPPTNNNNNNNNNSINNINNNTQRQPLNNNNNNNNNINRNNSNLYPSYADQPDILRSSQKDEYYKKLFEDQCFEMLTRITGPRFIMNRQSESKLLANTIYYLLTTMIGSQTLGEEYCNLRKIKDKTFSIPSIPDRIKLYFFHLLAPYLIKKSLPKLFQRHPKLYILKEIFPKFERLHLALFYFNGSYFEFSKRLSDIRYIFNRKIDQKRPKYDILGLLIIIQILLSTFMYLKENSFFLKQQQKDGGCNGDGEEDNQDLNKDIKIEQVDSVINNNNQDQNNNQEEEEEQKCTLCLEVRTHTTATICGHLFCWHCITEWCNNKEQCPVCRCPISIRTCVPLYNY
What is the function of this protein?
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity).  PEX10 also regulates PEX5 recycling by acting as a E3 ubiquitin-protein ligase (By similarity).  When PEX5 recycling is compromised, PEX10 catalyzes polyubiquitination of PEX5 during its passage through the retrotranslocation channel, leading to its degradation (By similarity).
What are the official names of this protein?
Peroxisome biogenesis factor 10, Peroxin-10, Peroxisomal biogenesis factor 10, Peroxisome assembly protein 10.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: UPP_NATTJ
Sequence: MSKLHVVDHPLIQHKLAFIRDKETGSKTFRELVNEVSMLMAYEVTRELQTEEYEVETPISTAKTRILSGKKLGLVPILRAGLGMVESVRNLIPAARVGHIGVYRDPETLQPVEYYCKLPQDIHERELIVLDPMLATGGSAKASIQFIKDRGGTNIRFMCINAAPEGVEELQKAHPDVDIWTCAVDEKLNEKAYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RBFA_FRATF
Sequence: MAAEGRVQRVASEFQKVISLLLRTRIKDAKLASATITEVDLSKDLSYAKIYYTCLAIEDAEYIDKAFEKSKGFFRSSIAKSLSLRIVPNLKFIYDTSLDYGMQMEEKIQQALEADSKIIKQDDKSLQENYKQNDKETKAEKLR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT4_HUMAN
Sequence: MDPRECVCMSGGICMCGDNCKCTTCNCKTYWKSCCPCCPPGCAKCARGCICKGGSDKCSCCP
What is the function of this protein?
Seems to bind zinc and copper.  Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia.
What are the official names of this protein?
Metallothionein-4, MT-4, Metallothionein-IV, MT-IV.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: HPPD_STRAW
Sequence: MTQTTHHTPDTARQADPFPVKGMDAVVFAVGNAKQAAHYYSTAFGMQLVAYSGPENGSRETASYVLTNGSARFVLTSVIKPATPWGHFLADHVAEHGDGVVDLAIEVPDARAAHAYAIEHGARSVAEPYELKDEHGTVVLAAIATYGKTRHTLVDRTGYDGPYLPGYVAAAPIVEPPAHRTFQAIDHCVGNVELGRMNEWVGFYNKVMGFTNMKEFVGDDIATEYSALMSKVVADGTLKVKFPINEPALAKKKSQIDEYLEFYGGAGVQHIALNTGDIVETVRTMRAAGVQFLDTPDSYYDTLGEWVGDTRVPVDTLRELKILADRDEDGYLLQIFTKPVQDRPTVFFEIIERHGSMGFGKGNFKALFEAIEREQEKRGNL
What are the official names of this protein?
4-hydroxyphenylpyruvate dioxygenase, 4HPPD, HPD, HPPDase.
What is the protein family that this protein belongs to?
Belongs to the 4HPPD family.
Protein: HCP_SHISS
Sequence: MIMFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKACEYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGDDFSAVITQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_IHNVW
Sequence: MTSALRETFTGLRDIKGGVLEDPETEYRPSTITLPLFFSKTDLDLEMIKRAVSQVGGEGTRKALSLLCAFVIAETVPSEAGTVAELLEALGFVLESLDTGAPPDATFADPNNKLAETIVKENVLEVVTGLLFTCALLTKYDVDKMATYCQNKLERLATSQGIGELVNFNANRGVLAKIGAVLRPGQKLTKAIYGIILINLSDPAIAARAKALCAMRLSGTGMTMVGLFNQAAKNLGALPADLLEDLCMKSVVESARRIVRLMRIVAEAPGVAAKYGVMMSRMLGEGYFKAYGINENARITCILMNINDRYDDGTSRGLTGIKVSDPFRKLAREIARLLVLKYDGDGSTGEGASELIRRAEMASRGPDMGEEEEEDEEDDDSSEPGDSDSFH
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the novirhabdovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: VL2_HPV04
Sequence: MQSLSRRKRDSVPNLYAKCQLSGNCLPDVKNKVEADTLADRLLRWLGSVIYLGGLGIGTGRGSGGSTGYNPIGAPSRVTPSGTLVRPTVPVESLGPSEIIPIDAIDPTTSSVVPLEDLTIPDVTVDSGDTRGIGETTLQPAQVDISTSHDPISDVTGASSHPTIISGEDNAIAVLDVSPIEPPTKRIALATRGASATPHVSVISGTTEFGQSSDLNVFVNATFSGDSIGYTEEIPLEPLNPFQEFEIESPPKTSTPRDVLNRAIGRARDLYNRRVQQIPTRNPALLTQPSRAIVFGFENPAFDADITQTFERDLEQVAAAPDADFADIVTIGRPRFSETDAGQIRVSRLGRRGTIKTRSGVQIGQAVHFYYDLSTIDTADAIELSTLGQHSGEQSIVDAMIESSLIDPFEMPDPTFTEEQQLLDPLTEDFSQSHLVLTSSRRGTSFTIPTIPPGLGLRIYVDDVGSDLFVSYPESRVIPAGGLPTEPFVPLEPALLSDIFSTDFVYRPSLYRKKRKRLEMF
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: YICR_SALEP
Sequence: MDTLDELLPREKMLRSGIASLSDVELLALFLRTGTPGKDVMTLAKEILQHFGSLYGLLSADFAQFRGVNGIGLAKFAQLKGIAELARRYYSVRMNEESALLSPEMTREFLQSQLTGEEREIFLVIFLDAQHRVLQHSRLFSGTLNHVEVHPREIVREAIKLNASAVILAHNHPSGCAEPSKADKLITERVIKCCQFMDIRVLDHLIIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: RL18_SHEAM
Sequence: MDKKSSRLRRATRARKKIQELGVHRLVVHRTPRHIYAQVINPEAQVVAAASTVEKSIKEALKSTGNVDAAKAVGKAIAERAVEKGVTVVAFDRSGFKYHGRVAALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.