PharMolix/UniProtQA huggingface dataset:
Protein: ARGI1_RAT
Sequence: MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYLKPPK
What is the function of this protein?
Functions in L-arginine homeostasis in nonhepatic tissues characterized by the competition between nitric oxide synthase (NOS) and arginase for the available intracellular substrate arginine.  Arginine metabolism is a critical regulator of innate and adaptive immune responses.  Involved in an antimicrobial effector pathway in polymorphonuclear granulocytes (PMN).  Upon PMN cell death is liberated from the phagolysosome and depletes arginine in the microenvironment leading to suppressed T cell and natural killer (NK) cell proliferation and cytokine secretion (By similarity).  In group 2 innate lymphoid cells (ILC2s) promotes acute type 2 inflammation in the lung and is involved in optimal ILC2 proliferation but not survival.  Plays a role in the immune response of alternatively activated or M2 macrophages in processes such as wound healing and tissue regeneration, immune defense against multicellular pathogens and parasites, and immune suppression and allergic inflammation; the regulatory outcome seems to be organ specific.  In tumor-infiltrating dendritic cells (DCs) and myeloid-derived suppressor cells (MDSCs) plays a role in suppression of T cell-mediated antitumor immunity.
What are the official names of this protein?
Arginase-1, Liver-type arginase, Type I arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic granule.
Protein: PHNC_PENHR
Sequence: MDQNTLIKTAQQILDTTTELSKHLAESDIAIPNDLNVGTTSGLWTTHNAEIEALRLKITGLSQNLGMLLEGPHGFLHEYVSVNWEHGALYTLLDHNVLEQIPLDGSKIAIADLATRVGLPADKLLRICRLVATVGIIREDTEGEFSHTAISETLVKDQGYKSFIGFQTFETRVASAHLADSLRKPNPYWNEGQAAFELAWGMPMYDWHREHPEKGKRFAQAMQSVSKNLDAGNDMIIQWVKGSEGLQNGKPLHVVEIQGKTGAFSAELATLYPNAEFEVQDTSADLISRGKQTLDPELASRVKFSQRDLFAVRKCDEVSDFTDNTVVFLLRGVLWNHSDEEVITLLRSFLPAMEHGIKPIVLISDLVSPIWATFESHVERAFRRRDVTLTTMHNVKQRTSTEWSQLLQSADPNFKVCAFPVDLFGIFEN
What is the function of this protein?
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of phenalenones such as herqueinone, compounds that have been reported to treat tumors, bacterial infections and/or mycoses, and rheumatic diseases (PubMed:26978228).  The non-reducing polyketide synthase phnA synthesizes the heptaketide backbone and cyclizes it into the angular, hemiketal-containing naphtho-gamma-pyrone prephenalenone.  The product template (PT) domain of phnA catalyzes only the C4-C9 aldol condensation, which is unprecedented among known PT domains (PubMed:28240554, PubMed:26978228).  The transformation of prephenalenone to phenalenones requires an FAD-dependent monooxygenase phnB, which catalyzes the C2 aromatic hydroxylation of prephenalenone and ring opening of the gamma-pyrone ring simultaneously (PubMed:28240554, PubMed:26978228).  Subsequent intramolecular deprotonation of C3 phenolic oxygen accelerates phenalenone ring closure to yield the tricyclic phenalenone core with a C2 hydroxylation (PubMed:28240554, PubMed:26978228).  The prenyltransferase phnF further catalyzes reverse C-prenylation of phenalenone by direct electrophilic substitution at C6, or possibly via first a forward O-prenylation of a neighboring phenol in phenalenone, followed by a Claisen rearrangement (PubMed:28240554).  The hydroalkoxylation enzyme phnH catalyzes the 5-exo-trigcyclization via acid catalysis after the spontaneous deprotonation of 7-OH, which leads to the formation of the dihydrobenzofuran atrovenetin (PubMed:28240554).  Atrovenetin is further converted to deoxyherqueinone by the O-methyltransferase phnC which can methylate C2-OH to stabilize the northern portion of the phenalenone core (PubMed:28240554).  Finally, the oxidoreductase phnG converts deoxyherqueinone to herqueinone via C6 hydroxylation (PubMed:28240554).
What are the official names of this protein?
O-methyltransferase phnC, Phenalenone biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: NUOH_WOLPM
Sequence: MNTLVNILFILVPLLLSVAYLTYFERKVLAAIQLRHGPSVVGPFGLLQPFADAIKLLIKEPIIPFRASTILFIMAPMLTFILALIAWAVIPFGAEVIVENGQQVIIPKVIANINVGVLYVLAISSLGVYGVIIAGWSSNSNYAFLGAIRSAAQMISYEVSIGLIVAAVVITTGTLNLGEMVVAKHNMPFWVDLLLMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALFFLGEYANMILASAMMTIFFLGGWYPPLEFSLLYKIPGLIWFVLKIVILLFIFIWIRATIPRYRYDQLMRLGWKVFLPISVLWVILISGVLLFTGNLPGSNV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROC_ZINIC
Sequence: MFCNILGKIFTISCFGESHGKVIGCIIGGCPSNIKLSNIDVQIEVNKRKPGISKYITSRKENDKIKILSGIFNKKTTGAPIAIIIKNNDKKSRDYDNIKNIFRPGHADYTYWNKYKNIDFRGGGHSSGRLTANIVSASSITKKYLFKNYGIVFKGYVKQIGKNKILFESWDLINFKLNIANIKKKNIIKKYIKYINKIGDSCGANINLIIKNLPIGIGNPIFDKLNSRISYYLMNINAIKAINIGNGIKGIKYKGSKFNDIITKKGFKTNNSGGILGGISTGQDIKISIFIKPTSSIKIPQKSINKFNKKVKFIIKGRHDTCIGIRILSVAESMLSLVIMDFILNFNSYKI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: METN_LIGS1
Sequence: MTDIITLENIDVTFKQGKQIVNAVKNVNLNVEKGDIFGVVGYSGAGKSTLVRTINLLQKPTSGTVKVNGTLLFADNKQQISNKELQKQRRSIGMIFQHFNLLNETTVVDNVAFALRHSSLSDKEIEEKALNLLKLVGLEDKAKFYPIQLSGGEQQRVAIARALANDPEILISDESTSALDPRTTNQILDLLKELNAKLGLTIVLITHEMDAVKRIANKIAIMEHGVIIEKGKLRDVYLRPKEELSRQFVGGSLAAIETLKAFNLGNLSPDQKLFQLVFSAANVTKSIILELYKELGLDVSMLYGNIEVLESEPVGTMFILAKGEPDKLDKVADYLKKENVEVTRIDERGIWND
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AGP1_ARATH
Sequence: MAFSKSLVFVLLAALLISSAVAQSPAPAPSNVGGRRISPAPSPKKMTAPAPAPEVSPSPSPAAALTPESSASPPSPPLADSPTADSPALSPSAISDSPTEAPGPAQGGAVSNKFASFGSVAVMLTAAVLVI
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.
What are the official names of this protein?
Classical arabinogalactan protein 1.
What is the protein family that this protein belongs to?
Belongs to the classical AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: 1A1D_ACIET
Sequence: MNLQKFPRHPLTFGPTPIQPLKRLSQHLGGKVELYAKREDCNSGLAFGGNKTRKLEYLIPEAIAGGYDTLVSIGGIQSNQTRQVAAVAAHLGLKCVLVQENWVNYSDAVYDRVGNIEMSRILGADVRLDAAGFDIGIRPSWEQAMADVKQAGGKPFPIPAGCSEHPYGGLGFVGFAEEVRQQEKELGFRFDYIVVCSVTGSTQAGMVVGFAADGRARRVIGIDASATPEKTHAQILRIAQSTADLVELGQDITAEDVVLDTRYGGPEYGLPNEGTLEAIRLCARQEGMLTDPVYEGKSMHGMIERVRNGEFPAGSKVLYAHLGGVPALNAYSFLFRNG
What is the function of this protein?
Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.  Allows growth on ACC as a nitrogen source.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate deaminase, ACC deaminase, ACCD.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: RF1_PORGI
Sequence: MSENNLLDRLDGLESRFEEISTLITDPAVIADMKRFTKLSKEYRDLEKIHTAGRDYRNLLANIEEAKHTMAKESDEELREMAREMLAEANERLPILEEEIKMLLIPANPEDDKNAIVEIRGGTGGDEAALFAGDLYRMYVKYCESKGWQVEVTDLSEGATGGYKEIVFSVKGEGVYGILKYESGVHRVQRVPATETQGRIHTSAATVAVLPEAEEVDVEINPADIEMQTSRSGGAGGQNVNKVETKVQLTHKPTGMVVVCQQARSQIANRELAMQMLRSKLYDIELSKHNEAIAARRKTMVSTGDRSAKIRTYNYPQGRVTDHRINMTVYNLSAVMDGEVQPFIDALIIAENVERMKEAAL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGT4D_RAT
Sequence: MKTKNVNLLFALVAVLLFGFSCFCISRMNQTNNQLINCRNHVLEFKETMLRLKNKSENNHQNLVKVLHQLKHKVAPAKPSGSILEKKVNMLDQDETVFNQFEVLKFFLPHLRTAGNIYPDIAIGRQRAGVSFALGITTIDRGNHTYLKQTLTSVLSRMTPEEEEDSVVIVSVADTDENYLKSVVHMVKTRFRKQVQSGALEVISIPALFYPQTLLEKKTTKNAKNWQIKQVLDFCILMLYAQPKATYYLQLEDDIVAKKMYFTKMKDFVNSVTSKDWFYIEFSVLGFIGKLFRSKDLMDFVHFFLIFYRAKPIDVLLDDIALLRMCSFGGPLRSCLQLKREVRVQYKPSLFQHVGTHSSFPGREQHLKDHYY
What is the function of this protein?
May play a role in male spermatogenesis.  In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans.  The function is mediated by its lumenal domain and occurs specifically in the Golgi.  A catalytic glucosyltransferase activity is not detected.  May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.
What are the official names of this protein?
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D, Glycosyltransferase 54 domain-containing protein, GL54D.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: PDXH_RHIEC
Sequence: MSANELTSGDFTESGEPFKLFAEWLKEAEASEPNDPNAVALATVDEHGLPNVRMVLLKGFDDDGFVFYTNFESQKGREILGQKKAAMCFHWKSLRRQVRLRGPVEIVSDAEADAYFKTRARGSRIGAWASKQSRPLESRFALEKAVAEYTARYAIGEIPRPPHWSGFRIRPTSIEFWKDQQFRLHDRIEFRRPSPVGAWEKVRMYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: YIDD_CLOBJ
Sequence: MKNLLICIIKMYRKYISPLKRPSCRFYPTCSQYSLEAIEKYGALKGTLISIKRILKCHPFNEGGYDPVK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRXF_BRANA
Sequence: MPLSLRLAPSPTALSPTTGGFSPAKKQCRIPSYSGVATTTRRIGLCSLDYVKRGDSSVVRCSLQTVNVSVGQVTEVDKDTFWPIVKAAGEKIVVLDMYTQWCGPCKVIAPKYKALSEKYEDVVFLKLDCNPENRPLAKELGIRVVPTFKILKDNQVVKEVTGAKYDDLVAAIETARSASSSG
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide.  The F form is known to activate a number of enzymes of the photosynthetic carbon cycle (By similarity).
What are the official names of this protein?
Thioredoxin F-type, chloroplastic, Trx-F.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant F-type subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DEN5A_HUMAN
Sequence: MSGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQASKARDGASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVEWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAEYDVLHAPPADDRDQSSMEDGEDTPVTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLEQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGIPPEGNLHCSESASKLKRLRASELVSDKRNGNIAGSPLHSYELLKENETIARLQALVKRTGVSLEKLEVREDPSSNKDLKVQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAIHPHLLDMKIGQGKYEPGFFPKLQSDVLSTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARTMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQDNRQRKLTSGSLSTSGILLDSERRKSDASSLMPPLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQIMQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILVGELLTSQPEVDERPCRTPPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGECGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEKNEVVPEENWHTRARNFCRFVTAINNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLETSLVKGIDI
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.  Involved in the negative regulation of neurite outgrowth (By similarity).
What are the official names of this protein?
DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1.
What is the protein family that this protein belongs to?
Belongs to the RAB6IP1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane.
Protein: GAR1_CRYNB
Sequence: MSGRGFSRGGGGGFRGGARGGRGGGRGGFQQRDMGPPDTVLEIGSFQHDVESEMLCSLTAPTKIPYFNAPIYLQNKTQIGKVDEILGPINEVYFTVKMEQGMLASSFKKEDKVYISGEKLLPIERFLPKPKVAGGKERGAQGGRGAPRGRGGAGSRGGRGGFSSRGGPGGRGGARGGAGGRGGFSSRGGGAPRGRGGFRGRGQ
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit GAR1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TRPA_KLEP3
Sequence: MERYETLFAQLKNRQEGAFVPFVTLGDPGPEQSLKIIDALIEGGADALELGIPFSDPLADGPTIQGAALRAFAAGVTPAQCFEMLAAIRQKHPTIPIGLLMYANLVFSPGIDAFYAQCARVGVDSVLVADVPVEESAPFRQAAMRHNIAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLHHLVEKLAEYHAAPPLQGFGISAPEQVSAAIDAGAAGAISGSAIVKIIERHLDEPQTMLDELKAFVQSLKAATKTA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: AROC_STRS7
Sequence: MRYLTAGESHGQALTAIIEGIPAGLTLSAELINKELKRRQGGYGRGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKLKRKITHPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAVAKVVLTELGIETANHVLVFGGIEVAVPEAMPFTDIKKAAEASDLSIVNPKQEATIKAHIDQVKKEGDTLGGIIETIIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDEIIWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKATVERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYCDYVHHF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: OST4_RAT
Sequence: MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNPKKQE
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.  Specifically involved in maintaining stability of STT3A-containing OST complexes.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the OST4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Single- pass type III membrane protein.
Protein: YFBU_ECOL6
Sequence: MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQMRELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEARYLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQIINA
What are the official names of this protein?
UPF0304 protein YfbU.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: Y192_ATV
Sequence: MVRIIAMGQSPLCNFIKEQLKMNIIVYPEFFDNKKLLLQRRVRDYIISLLRNYRKIRYALYPDYYYRDINLPAEITEKITFIYPVHSKNEVEFIAKLKSKYNIIPGFASDSRYRDYDIYWFVNTFREEKWYLGISTWRELREAKRFEFYGGDITGFVLGNHEDRKNPEVLRRKLKEIIEYVSRPQGKQLTLF
What are the official names of this protein?
Uncharacterized protein ORF192.
Protein: GBRG1_HUMAN
Sequence: MGPLKAFLFSPFLLRSQSRGVRLVFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit gamma-1, GABA(A) receptor subunit gamma-1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: EF2_PONAB
Sequence: MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Protein: MSR1_ARATH
Sequence: MGVDLRQVVAGILTITMFVMLGQMLHRDYFDSLQEKAQGDAQDIEFEGSKVSVKDGLVGTVEGSKGLWMEDNTDLTPCWPTLLSDDAVSSKGYVTFSLTNGPEYHISQITDAVMVAKHLGATLVLPDIRGSKPGDERNFEDIYDADKLIKSLENVVKVVKKLPEEVSLRNMAIVKVPTRVTEDYIKEHIDPIFKSKGNIRVASYFPSVNLRKSSQDGETDPVACLAMFGSLELQPEVNAVAESMVERLRTHSRKSGGRFIAVDLRIDILEKKNCHTTGVVGSKTCYNAQEIALFLRKLGFASDTTIYLTQPRWDSSLNILKDIFPKTFTKEAIMPASKRSKYLESVSSEYENVIDFYISSRSDVFVPAISGLFYANTVGKRIALGKPQVLVPAEISETSGLATDFISPYISKKNHLAYSCFC
What is the function of this protein?
Glycosyltransferase involved in mannan biosynthesis.
What are the official names of this protein?
Protein MANNAN SYNTHESIS-RELATED 1, AtMSR1, O-fucosyltransferase 25, O-FucT-25, O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: BI1_DROME
Sequence: MADTANYINDRFQTFMNGLGDRYEPYVREHLSKVYMVLGSTAAATAMGAMLQMRDFLDLGVLAAVATLVLVLGLHFYKDDGKNYYTRLGMLYAFGFCSGQTLGPLLGYICSINPAIILSALTGTFVTFISLSLSALLAEQGKYLYLGGMLVSVINTMALLSLFNMVFKSYFVQVTQLYVGVFVMAAFIVYDTQNIVEKCRNGNRDVVQHALDLFFDVLSMFRRLLIILTQKEERKQNERRQNKTK
What is the function of this protein?
Suppressor of apoptosis (By similarity).  Modulates unfolded protein response signaling (PubMed:19328063).  Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (PubMed:21926971).
What are the official names of this protein?
Bax inhibitor 1.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.