PharMolix/UniProtQA huggingface dataset:
Protein: APAH_SALPB
Sequence: MATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGIYALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: MURD_CLOD6
Sequence: MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRNILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELAFKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESVLVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCVLNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLPGGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTNPDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKNKGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNLK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUMH_PIG
Sequence: MDRALRLLARSRCLSRVPASAPGPGPGSSPSGVSRLLLRPPNAARMASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVNKSQSSNDTFPTAMHIAAAVEVHEALLPGLQKLHDALDAKSREFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAITRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEALTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDAAVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKATAVELGYLTAEQFDEWVKPKDMLGPK
What is the function of this protein?
Catalyzes the dehydration of L-malate to fumarate.  Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity).  Also plays a role in DNA repair by promoting non-homologous end-joining (NHEJ).  In response to DNA damage and phosphorylation by PRKDC, translocates to the nucleus and accumulates at DNA double-strand breaks (DSBs): acts by catalyzing formation of fumarate, an inhibitor of KDM2B histone demethylase activity, resulting in enhanced dimethylation of histone H3 'Lys-36' (H3K36me2) (By similarity).
What are the official names of this protein?
Fumarate hydratase, mitochondrial, Fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm, cytosol. Nucleus. Chromosome. Note=Translocates to the nucleus in response to DNA damage: localizes to DNA double-strand breaks (DSBs) following phosphorylation by PRKDC.
Protein: RL28_FLAJ1
Sequence: MSRVCDLTGKRAMVGNNVSHAMNKTKRKFSVNLVKKRFYLPEEDRWITLRVAASTIKTINKNGITAVLKKAQSEGFIK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: B1Q_LOXIN
Sequence: MQLFIILCLAGSAVQLEGTELDGVERADNRRPIWNIAHMVNDKGLIDEYLDDGANSVESDVSFDSNGKPEKMLHGSPCDCGRSCKRQMSFADYLDYMRQLTTPGDPKFRENLILVMLDLKLKKLSSEQAYSAGQEVASQMLDKYWKRGESGARAYIVLSIPTITRVTFVNGFYDKLHSEGFDQYREKVGVDFSGNEDLEDTGKILKSRDILDHIWQSDGITNCLFRIMKRLKAAIRKRDSNGYMVKVYTWSVDKYTTMRKALRAGADGMITNFPKRLVSVLNEREFSGKFRLATYNDNPWERYTG
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) with low activity (PubMed:17296256).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Has no or weak activities in inducing dermonecrosis, hemolysis, inflammatory response, platelet aggregation and increase in vessel permeability (PubMed:17296256, PubMed:21590705).  In vivo, shows no lethality when injected at higher dose into mice (PubMed:17296256).
What are the official names of this protein?
Dermonecrotic toxin LiSicTox-betaID1, Dermonecrotic toxin 5, DT5, LiRecDT5, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 5, SMD 5, SMase D 5, Sphingomyelinase D 5.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily. Class IIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRD_PSEFS
Sequence: MYTLARQLLFKLSPETSHDLSLDLIGAGGRLGLNGLVCKAPAKVPVSVMGLDFPNPVGLAAGLDKNGAAIDGFAQLGFGFVEIGTVTPRPQPGNPKPRIFRLPEAEAIINRMGFNNLGVDHLLSRVQAAKYQGILGINIGKNFDTPVERAVDDYLICLDKVYAHASYVTVNVSSPNTPGLRSLQFGDSLKQLLEALRQRQEDLAVRHGKRVPLAIKIAPDMSDEETVLVAQALVDSGMDAVIATNTTLSRVGVEGLAHGDEAGGLSGAPVRDKSTHIVKVLAAELAGRLPIIAVGGITEGKHAAEKIAAGASLVQLYSGFIYKGPALIRQSVDAIAALPKA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLHA_LITCT
Sequence: FPDDNFLTPGCPECRLKENLRFSNMGIGRIYQCSGCCYSRAYPTPMRSKKTMLVPKNITSEAKCCVAKTQYRVTVMDNVKIENHTACHCSTCLYHKS
What is the function of this protein?
Shared alpha chain of heterodimeric glycoprotein hormones.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.  Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURD_DESVH
Sequence: MTCDKEKTRGIRPGDIAVVVGTGRSGVAAARLLHAKGARVRVLERDAANVPATFAEWAAGAGVEIVCGAHDAAHFADAAVVVPSPGVAVATLRPYLPATGGPEVMAEMELAWRELSGEPVIAVTGTSGKTTTVSLCAHMLRTQGLSVFLGGNIGTPLCEYVLEGKRADVLVIEISSFQLQTCSTFRPRVAMLLNITANHLDYHADMQEYIDAKFRLFRCQDEDDLAVFGEGLAPLVDRYGVKARRVTFRATDRFAESRLFGAHNRANAEAAWTAAREFGVTLENALQAVATFAPMPHRLEQVAERGGVLYVNDSKCTTVSALRVALEAFDRPVLLLAGGKFKGGDLEGLIPLVRERVRAVMLFGASREVFEAAWRDVVPMTWDATLEEAVRRAASAARQGEVVLMAPATASFDLFRNYGHRGDVFRAAVESLA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATF_PICST
Sequence: MIRINSRGLTVSTRRFQTLSKIGSTLKTKEDIRNALNSPVWSLKELISSNEKDMKSVEVSAKTINKVLKLSAFDTNITAEQEKSLVSALSAQMVFIKHLYENDEKSDSVVEENDTHFRLIASDHNPGEPLTLKQLLAQIEELPEKVDPAKGETQGSFNVANMNPRNRPFATIRSKQG
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  Required for proper protein synthesis within the mitochondrion.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial, Glu-AdT subunit F.
What is the protein family that this protein belongs to?
Belongs to the GatF family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: DCD_HISS2
Sequence: MRLCDTDIERYLDQGIISLTPRPSNEKINGATIDVRLGNSFRVFREHTAPFIDLSGPKEEVTAQLDAVMSDEIIIGENEAFFLHPGELALATTLEAVKLPANIIGWLDGRSSLARLGLMVHVTAHRIDPGWEGKIVLEFFNSGKLPLALRPNMVIGALSFEVLSGTAARPYTSRKDAKYKHQQSAVASRISEDK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ATS3A_ARATH
Sequence: MLRLAIPLFLFALCSFTLFSSARSFITTKPLPIDSFIPKPKLENAAACSYTVIIKTSCSSVSYTRDKISISFGDVYGNEVYVKRLDDPSSRTFEKCSSDTYKISGPCMRDVCYLYLLRQGSDGWKPENVKIYGSSIRSVTFYYNLFLPNSVWYGFNVCNGIGNTKSSQPISTTSSVAAM
What is the function of this protein?
May play a role during embryo development.
What are the official names of this protein?
Embryo-specific protein ATS3A, Protein ARABIDOPSIS THALIANA SEED 3A.
What are the subcellular locations of this protein?
Secreted.
Protein: JIP4_YEAST
Sequence: MVVRDQDEALRNSYKYVKLYVRQDQLEDTVDILAKQDEDKSNNDDRRSLASILDSSSSVKKKGKGSNEKYLPCVSFNTVPRSRVSSPLDEEKREFPGVQISADYTMEEYYDDESGFTSDNNADYFSGNSYSSRREGSASPGRYSSPPPASKRNIKIGKMFKISENGKIVREDYPTTPTDINDALVISRAYANWRQLWIKKKNQIDHRLEQKRDFFNYPTILFPPNKKKSSEGATPTIKFNPPIEDGFTPLTKSQKRKERVLSEKVGFPNTPRTILCHISGRKHTWVALDWALRTLIQNTDHIVVLANLPRLTKNNFEDNDSMSERKRMLMMMDDSRSVSSARRSRSRSRSRSICTRRALSLGPEESDNKLKHQNFIEWTSGYTQNEIERKLQDLFDYVTLIIPQDRSVKVTVEILIGKTKKTLLEAINIYLPDFFVSSTLRWERTDSLVRWKSNFLTDKLCTNFPIPTFIVPAKRMFDLEIDLQKEFKEPEVTKQKNTSGPKPGFSHSKSADASIPTISNIKRKQDNDYSIDSLCYAPEANGANNSSREEASDDELNAFKDDENDVMSVKSLTSNISVKEKLCTMARKRRKSMAQQLNDADHDSSIPPGQRHLKKLNIILESSLKFSLEIDSITDSIENGDVDEKRAHSMESGFEELKRVITGGAPPRHVATPQRSMLDVLDNPSSSRSKSKSRSSSKSRIRDKSKPSSPTATDINSSASASRSRSPQIKFASSVKNVDGNAALGAIKSRHSLDSPGDQQQQHHHHHHRDTDQLSVPGLPHLAPSKSYSVSSGNKDSSLRKVSSSSSLRKVKSNDSNSGKRIKKPVVTSAHLKPSSGGGGLFSFFKSKSRSPSSFRKEDESKNTPKRGGLFGFGRL
What are the official names of this protein?
Uncharacterized protein JIP4, Jumonji-interacting protein 4.
Protein: YCF37_CYAPA
Sequence: MDNFLFSFYIIFFSLIVLALISFLIQEIQKSRFLDLEITRLRKKIYQEKATEKDYNNLASIYIKKKLYSQAQKEFLKILENKNLDKSQLALIYNSLGYICSAQEQYELAIEYYKKALFYIPDFILARINLARIFELKNLKTEAINMYQEVLIFDPKNQLAKRKLSIIENLIL
What are the official names of this protein?
Uncharacterized protein ycf37.
What is the protein family that this protein belongs to?
Belongs to the ycf37 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: ORF24_TTVV6
Sequence: MPWRPPAHSVPGREGQFYAATFHAHAAFCGCGGFIEHLNSIHPRFLGAGGPPPPPPALRRALPAPEGPGGPPQHAPPNPPPEGDHQPPRRGGGAGGAGDGHAGDGDAAEEYGPEDLDLLFAAAAEDDMSFKAPSSRHQTRGPGRRAKKRLRFSPGSPRQPRLGGESRRSPSPRRTSTPKRKRGATPQAAPAAKTTPASPQTRTPSPVRRRTQTEEGSPHRPPPYIAPPPIVEDLLFPNTQKKKKFSKFDWETEAQLAACFDRPMRFFPSDLPTYPWLPKKPTTQTTFRVSFQLKAPQ
What are the official names of this protein?
Uncharacterized ORF2/4 protein.
Protein: IL2_AOTVO
Sequence: MYRMQLLSCIALSLALITNSAPTSSSTKKTQLQLEHLLLDLQMLLNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRDTRDIISNINVLVLELKGSETTFTCEYDDDTATIIEFLNGWITFCQSIISTLT
What is the function of this protein?
Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance.  Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG).  Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3.  In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5.  This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways.  Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well.  Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production.  Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance.  Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
What are the official names of this protein?
Interleukin-2, IL-2, T-cell growth factor, TCGF.
What is the protein family that this protein belongs to?
Belongs to the IL-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP6_BACP2
Sequence: MGHSSKTTEFLGLTFNLSNVLMITIASIIVLLIAVLTTRVLSIRPTKAQNFMEWIVDFVRNIIGSSMDMKTGAPFLALGVTLLMYIFVSNMLGLPFSISVDHNLWWKSPTADPAITMTLAVMVMGLTHYYGVKAKGVKEYTKDYFRPIPLLVPLKIIEEFANTLTLGLRLYGNIFAGEILLGLLAGLATNFYSQNIALGIIGTLGAIVPMIVWQAFSLFVGTIQAFIFTMLTMVYISHKVSDEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZN363_MOUSE
Sequence: MAATAREDGVRNLAQGPRGCEHYDRACLLKAPCCDKLYTCRLCHDTNEDHQLDRFKVKEVQCINCEKLQHAQQTCEDCSTLFGEYYCSICHLFDKDKRQYHCESCGICRIGPKEDFFHCLKCNLCLTTNLRGKHKCIENVSRQNCPICLEDIHTSRVVAHVLPCGHLLHRTCYEEMLKEGYRCPLCMHSALDMTRYWRQLDTEVAQTPMPSEYQNVTVDILCNDCNGRSTVQFHILGMKCKLCDSYNTAQAGGRRVPVDQQ
What is the function of this protein?
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B.  Preferentially acts on tetrameric p53/TP53.  Increases AR transcription factor activity.  Monoubiquitinates the translesion DNA polymerase POLH (By similarity).  Contributes to the regulation of the cell cycle progression.
What are the official names of this protein?
RING finger and CHY zinc finger domain-containing protein 1, Androgen receptor N-terminal-interacting protein, CH-rich-interacting match with PLAG1, E3 ubiquitin-protein ligase Pirh2, RING-type E3 ubiquitin transferase RCHY1, Zinc finger protein 363.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm.
Protein: ARP5_ARATH
Sequence: MAFVSRIRRQSDYNTYPSSIPIVIDNGASYFRIGWAGETEPRVVFRNIVQRPRHKATGETVTIVGDLDPSMMKYFDCTRSGPRSPFDSNVVYQFEIMEYILDYAFDRLGANGSGIDHPILITECACNPVQSRSKMAELLFETYGVPAVAFGVDAAFSYKYNQLHGICKKDGIVLCPGFTTTHSIPFVDGEPIYKGSSRTNIGGYHVTDYLKQLLSLKYPFHSSRFTWEKAEDLKLEHCYIAPDYASEIRLFQEGRKEAEEKTSYWQLPWIPPPTEVPPSEEEIARKAAIREKQGQRLREMAEAKRVSKINDMENQLISLRFLLKQVDQVEEDDIPTFLSDTGYASRQELESTITKVTQSLRKARGEPKNEPAEYEENPDSLNNEKYPLMNVPDDILTPEQLKDKKRQMFLKTTAEGRLRARQKRNEEELEKEKRNQLEEERRRENPESYLEELQAQYKEVLERVEQKKRLKTNGSSNGNNKSGGIGRGERLSAAQRERMRLLTTAAFDRGKGEDTFGSRDEDWQLYKLMSKDNDDDDEQPDSDEAELARLSSRLQEIDPTFVQKVEGELSQTSGEVPRVRPLTEEDYKIVIGIERFRCPEILFHPNLIGIDQVGLDEMAGTSIRRLPHDEKELEERLTSSILMTGGCSLLPGMNERLECGIRMIRPCGSPINVVRAMDPVLDAWRGASAFAANLNFLGNAFTKMDYDEKGEDWLRNYQIRYNYL
What is the function of this protein?
Probable subunit of a chromatin-remodeling complex.  Involved in DNA repair.  Required for multicellular development of all organs.
What are the official names of this protein?
Actin-related protein 5.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP5 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Cytoplasm. Note=Localized in the nucleoplasm of interphase cells (PubMed:19679120). However, dispersed into the cytoplasm in dividing cells at metaphase (PubMed:19679120).
Protein: YPS3_YEAST
Sequence: MKLQLAAVATLAVLTSPAFGRVLPDGKYVKIPFTKKKNGDNGELSKRSNGHEKFVLANEQSFYSVELAIGTPSQNLTVLLDTGSADLWVPGKGNPYCGSVMDCDQYGVFDKTKSSTFKANKSSPFYAAYGDGTYAEGAFGQDKLKYNELDLSGLSFAVANESNSTFGVLGIGLSTLEVTYSGKVAIMDKRSYEYDNFPLFLKHSGAIDATAYSLFLNDESQSSGSILFGAVDHSKYEGQLYTIPLVNLYKSQGYQHPVAFDVTLQGLGLQTDKRNITLTTTKLPALLDSGTTLTYLPSQAVALLAKSLNASYSKTLGYYEYTCPSSDNKTSVAFDFGGFRINAPLSDFTMQTSVGTCVLAIIPQAGNATAILGDSFLRNAYVVYDLDNYEISLAQAKYGTGKENVEVIKSTVPSAIRAPSYNNTWSNYASATSGGNIFTTVRTFNGTSTATTTRSTTTKKTNSTTTAKSTHKSKRALQRAATNSASSIRSTLGLLLVPSLLILSVFFS
What is the function of this protein?
Cleaves proteins C-terminally to mono- and paired-basic residues.  Required for cell wall integrity.
What are the official names of this protein?
Aspartic proteinase yapsin-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=GPI- anchored plasma membrane protein (GPI-PMP).
Protein: RL31_PSYIN
Sequence: MKNAIHPEYKEITATCSCGNIVTVGSTAGKNLTLDICGECHPFYTGTQRVVDTGGRIEKFKNRFGALGKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: TIM14_EMENI
Sequence: MASALTLGLGVATAAFLGRAGLVAYRRSKGGVNALGKAFYKGGFEPRMNRREAALILELPERTLNKEKVRKKHRQLMLLNHPDRGGSPYLATKINEAKEFLDKHT
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  In the complex, it is required to stimulate activity of mtHSP70 (SSC1/sscA) (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim14, Presequence translocated-associated motor subunit pam18.
What is the protein family that this protein belongs to?
Belongs to the TIM14 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: T2S1_STRCS
Sequence: MINDQLPRWVREARVGTRTGGPAMRPKTSDSPYFGWDSEDWPEVTRQLLSEQPLSGDTLVDAVLASWESIFESRLGSGFHIGTQIRPTPQVMGFLLHALIPLELANGDPSWRADLNSSEKDLVYQPDHKYSIEMKTSSHKDQIFGNRSFGVENPGKGKKAKDGYYVAVNFEKWSDAPGRLPRIRTIRYGWLDHTDWVAQKSQTGQQSSLPAVVSNTQLLAIHTGGQR
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-AGTACT-3' and cleaves after T-3.
What are the official names of this protein?
Type II restriction enzyme ScaI, R.ScaI, Endonuclease ScaI, Type-2 restriction enzyme ScaI.
Protein: FENR_LEUCK
Sequence: MAQEIYDIAIIGGGPVGMFAAFYAGLRDTKVILLESLATLGGQVTSLYPEKTILDVAGFSATKGTDFIAALSQQLQRFPVDIRTQTTVVNLEKSGNLFTVTTNNGTFIQAKTVIVATGKGAFEPRKIQVAGVDNLVGQGVHYFIKNKHDFDNHHIAIAGGGDSAVDMATMLSHIAAETTLIHRRDNFRAMEQSVKTLMASKVIRETPKKILSVSKQPDGRLKLRLAHVKDNQQVNDIIVDDLIINYGFISENKTIQAWAVQPKLAGQVFAVNQTLETNVPGLFVIGDASHYIGKADLIAIGLGEAPSAVNAAIRCFDPNRGGPGHSSSMVLKDTIVRND
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RL17_AERS4
Sequence: MRHRLSGRQLNRNSSHRQAMFRNMASSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNAIVAKLFNELGPRYLERAGGYTRILKCGFRAGDNAPMAYIELVDRPAAAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y3713_CLOAB
Sequence: MAQISVTPEELKSQAQVYIQSKEEIDQAIQKVNSMNSTIAEEWKGQAFQAYLEQYNQLHQTVVQFENLLESVNQQLNKYADTVAERDAQDAQSFGF
What are the official names of this protein?
Uncharacterized protein CA_C3713.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. sagEsxA-like subfamily.
Protein: CMOA_ECODH
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHNAGFEHSELWFQCFNFGSLVALKAEDAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: DNAG_DEIRA
Sequence: MVGEYVRLTPAGKGRLKGLCPFHKEKTPSFQVDTEKGYYHCFGCKASGDVFGFVQQMEHLSFGDALRKLADRAGIQIDAKYGEKVSRDLYEVNAFALDYFRSHLPGPALDYLRGRGLSDETIAAFELGYAPDGWDGLLKLARTKGVSEKQLLEAGLLTENPENGRVYDRFRGRVMFPIRDHLGRLVGFGGRVLDDSKPKYLNTPETAAFKKGELLYGLDKARSGLGGGAELVVVEGYMDVISMHQHGFTGAVASLGTALTAEHAQLLERLGAQSIVLMFDQDGAGLKATLAGLDQVIGAKFRVRATSVPSGKDPADALLAGDDAGIREALAGGLDEVKYRVQAATEKYGVDTNEGKRRVLMELLPRMQNLDPLDAIAQDMRGAACELLGIRPEALLDWITSKAKRRTLTDTHLAGMSQSSGEEEHELALLRQLLVDPSLLAKLDGSLPWRNEAVRKVMLAAQGARSPDDILDIFRGQPEEQLLIRLMFEGRDSGSLSRASSQEYEQKVTTYAAHAVDDIQVTLNIDALKTEVDLLKKQLLSTPPAEQLALLSQIQELQRAIEAEKRARRGS
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: FMP49_YEAST
Sequence: MYYFSRVAARTFCCCIFFCLATAYSRPDRNPRKIEKKDKKFFGASKNTNPANAMGNLFKAPTIEYVVEEVTRTHQPEQYDIPTDMSPLMTIAASESADKFTDKFFVDQSSIMKEKTSSKGNARTLL
What are the official names of this protein?
Protein FMP49, mitochondrial, Found in mitochondrial proteome protein 49.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SRSF6_HUMAN
Sequence: MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD
What is the function of this protein?
Plays a role in constitutive splicing and modulates the selection of alternative splice sites.  Plays a role in the alternative splicing of MAPT/Tau exon 10.  Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC.  Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.
What are the official names of this protein?
Serine/arginine-rich splicing factor 6, Pre-mRNA-splicing factor SRP55, Splicing factor, arginine/serine-rich 6.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.