PharMolix/UniProtQA huggingface dataset:
Protein: SPC25_CRYNB
Sequence: MAPTTYAVPPRPASLHFLLESSTSKNGVPSLDLRWEPFQRHIESFLNAIDAYTQAARTEIVARATDHTAAVRDLKADKEEMERGIQLQRESEGEMLATLEAERHVVADLNASLSHLQSSLTKIKEKSSALDAELQSERKEVKAMQAEKERQTNVLNNMRERDTTELKQLEEALGWRVEGIKQDQLLMRFTLIDPEDPAREFSIIVDVSKQVYSVPNCDPPIPSLPDLVRQLNFDRDLFAFIKRVRIAFRALIPNPPNPSTKFDDLTGPSRSR
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein SPC25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: CCM1_PICST
Sequence: MLRYARTVRFSQVGNSVRTSSGSFGPIRTIFISSHDRKSPSHSLSPISNLPNHNDSSTERARKTLDDDFQRKIKYDELKTRKRIEDLRALTKKVSQLVKQKQELSKIAKIPVPSDEIKKLKSVEDVVKVTKSQHVATVRTNIPEPETVTTHIEKEESEFVMEQNAFIVPATPIPEEIAKRLGLALRYLVSETNQNWTLVLDQLKADRGFKDLPYTTVVDFLTKIPASELQKVIPKVDQLLKEAKIPKTAKILNLYIASLASGSAVPNQVIQILENYCKRIRKLKKGKLPKRTCEVMVQAYGKNGNINRIQDLLSEMKLHKIEISGMALTNILATCVYKARDHKQAVEIFDTMRFQKEVYKPGTRAYQDIIVSYVNNDDIEKAIDIYREMITEKIEPNQQIMVALARGCASREAFKFKSWDFIFEINRNNWTPTLPTYEYMLYLSSRDGDLALTRALYSRLLKDNTVSLRSFNFLLLAYSKARLSDDLGEPFLINADEKGRKFRFNVIDRSGISDPTNQFPFLPFNELTTKEQIMAESSAIWAHACLNNSELINSESTTSYLNIASERGTLSDFIDRMEGSTFLDEKINNVLSGVVIEEPDVVVETTDFLTQKSSAHEKYDETSIVKSPILKSIQSKRTPRVSLTYVVALKAAGKFNNYNFANRIWQERGKFRKTETFKKLPRTEKDKLDFQFATQMVRTLTELNLLEDALAVLKSTEYQFRWTWKELDVLKSAAIRQGNTNVAQTVRSIARRAQLTYEGKIRRKDYKRYVMQRGY
What is the function of this protein?
RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts.  Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity).
What are the official names of this protein?
Mitochondrial group I intron splicing factor CCM1.
What is the protein family that this protein belongs to?
Belongs to the CCM1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CATT_YEAST
Sequence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
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase T.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_DEHMC
Sequence: MSERIFIGVAWPYANSQLHLGHVAGAYLPADIFARYHRTRGDEVLMVSGSDMHGTPITIRAEQEGITAAEVAERYHQRFMASWPKLGISWDFYTSTATANHARTAQEMFLSLYEKGYIYKNTVCQPFCSHCNRFLPDRYVEGTCPHCKYEGARGDQCDNCGKPLNAAELLNFRCKNCGNPPEFRETEHFFLKLSAFEEELIRWVETKTHWRTNVLNFTLRYLKEGLKDRAITRDLDWGVPLPLPGYEGKRLYVWFEAVIGYLSASKEWAASKGQPNAWQKYWGGDTKSYYFIGKDNIPFHTIIWPAMLMGKGGLNLPYDVPSNEYLTTESQKFSKSRNNAIWVDDVLSRYGVDTLRYLLSANMPESSDTDFSWREFVRRNNDELVATYGNLAQRVLTMVCRNYDNKVPEYGELDERSLTLIEKTAAMLCETDKALYNCNFREAIRLAMALAQEANRYLDEKAPWKEIKVDKAAAARSLYVAMVALSGLRVAFYPFLPESSGRLSTYLGFGSELEKESWILKMPVVGQELTPPEPLFKKLEDSVVEEETARMGL
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXL2B_LITCT
Sequence: MGNVDLAKLGAILVKNAITGETVEFQTLWKDNTSVIFFLRRFGCQICRWIAKDVSQLKESLDANQIRLIGIGPETVGLQEFLDGKYFTGELYLDESKQSYKELGFKRYNALSIVPAALGKKVRDIVTKANADGVQGNFSGDLLQSGGMLVVSKGGEKALLHFVQDSPGDFVPLDTLVTALGITADVTSSQRPECNDEVCTR
What is the function of this protein?
Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor.  Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity).
What are the official names of this protein?
Prostamide/prostaglandin F synthase, Prostamide/PG F synthase, Prostamide/PGF synthase, Peroxiredoxin-like 2B.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: NU3M_ELITY
Sequence: MNAIVILFINATLSLGLITVAFWLPHLNIYAEKAGAYECGFDPMSSARLPFSMKFFLIGITFLLFDLEITLLLPLPWAMHSTNTYFTMLVSFLLVSVLALGLMYEWTNKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NADE_CARHZ
Sequence: MRVNWEEKTEKLVNWLREKTREANASGLLVGLSGGVDSAVVATLIKKAFPEKSLGIIMPCFSNPEDEEDARMIANHLNLKYIVVNLDEPYQALVSSLKNATPHEPEKLALANIKPRLRMTTLYYWAANLNYLVAGTGNRTELEIGYFTKWGDGGVDLLPIGNLTKTEVWEFARYLGLPEKIITKAPSAGLWEGQTDEGEMGFTYKDIDHYLLTGEGSAELVDFVKRMQRKSQHKKRIPEVPML
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: CCMB_HAEIN
Sequence: MIFLEIIKRELQIAMRKNAEILNPLWFFLLVITLFPLVIGPDPKLLSRIAPGIAWVAALLSALLSFERLFRDDFIDGSLEQLMLTAQPLPMTALAKVVAHWLLTGLPLILLSPIAALLLSLEVNIWWALVLTLLLGTPVLSCIGAIGVALTVGLRKGGVLLSLLVVPLFIPVLIFASSVLEAAGLNVPYGGQLAILGAMMVGAVTLSPFAIAAALRISLDN
What is the function of this protein?
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Heme exporter protein B, Cytochrome c-type biogenesis protein CcmB.
What is the protein family that this protein belongs to?
Belongs to the CcmB/CycW/HelB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPMI_PSEPF
Sequence: MTTTPKPLVLMILDGFGHSDSPESNAVYAAKKPVLDRLWATVPNGLISGSGMDVGLPDGQMGNSEVGHMNLGAGRVVYQDFTRVTKAIRDGEFFENPTICAAVDKAVAAGKAVHFMGLLSDGGVHSHQDHLIAMAELAFKRGAEKIYLHAFLDGRDTPPKSAASSIELLDATFQALGKGRIASLIGRYYAMDRDNRWDRVAQAYNLIVDGKGEINAATAQEGLEAAYARGESDEFVKATSIGEPVKVEDGDAVVFMNFRADRARELSRVFVEDGFKEFERARQPKVQYVGLTQYAESIPAPAAFAPGSLENVLGDYLAKNGKTQLRIAETEKYAHVTFFFSGGREEPFPGEERILIPSPKVATYDLQPEMSAPEVTDRIVEAIENQRYDVIVVNYANGDMVGHSGVFEAAVKAVECLDTCVGRIVEALEKVGGEALITADHGNVEQMADESTGQAHTAHTTEPVPFIYVGKRDLKVREGGVLADVAPTMLKLLGLEKPAEMTGTSILV
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: HIS82_BURMA
Sequence: MSRYWSDIVRQLEPYVPGEQPALAHPVKLNTNENPYPPSPRALDAIRRELGDTGEALRRYPDPVARRLRETVAAYHGIAPEQVFAGNGSDEVLAHAFQALLQHDRPLRFPDITYSFYPTYARLYRVAYETVPLAGDFSIVVDDYLDDAGCVLFPNPNAPTGRALPLADIERIVAANPSSVVVIDEAYVDFGAESAVSLIARYPNLLVVHTVSKARSLAGMRVGFAFGDAALIDALTRVKDSFNSYPLDRLAQVATQASYEDEAWFQATRKQVIASRERLVGALAALGFDVVPSAANFVFARPRSHDAATLAAQLKQREIFVRHFKLPRIDQHLRITVGSDAECDALVAALRELLAA
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SEPF_SALAI
Sequence: MGALRKAGVWLGLVEEDDERAYDDAGYDKGGYRESRYRSSRYSEDFGDEDDEDEEAAVPRSRRGDRSRLERAAARSGDVDHNVEGEQPERVERASVRSITRSAEPSESLTYHTRDNLALAPQPVRERVPADEEQRYQITTLHPTTYREARTIGEHFRDGVPVIINLTEMDEADARRLVDFAAGLAFGLRGTIERVTNRVFLLSPANVQVTAEDKAKIAEGGFFSLS
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RL16_BURO1
Sequence: MLQPKRRKYRKEQKGRNTGKATRGNAVSFGEFGLKAIGRGRLTARQIEAARRAMTRHIKRGGRIWIRIFPDKPISQKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVTEELAREAFRLAAAKLPLKTAFIVRQLGA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: VIF_HV192
Sequence: MENRWQVLIVWQVDRMKIRTWNSLVKHHMYVSRRASGWYYRHHYESRHPKISSEVHIPLGEARLVIITYWGLQTGERDWHLGHGVSIEWRLRRYSTRVDPGLADQLIHMHYFDCFADSAIRKAILGHRVSSRCDYQAGHNKVGSLQYLALTALIKPKKIKPPLPSVKKLVEDRWNKPQKTRDRRGNHTMNGH
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: UPPP3_BACCR
Sequence: MNWLEAFILGIIQGLTEFLPISSTGHLYLGRHLFRLDEAGLFLDTMLHIGTLLAVFIYYKKEFIYLIKNPFSKLMLLLIVGTIPAVVIGLLFKDFFEDISKTGITIGWEFLVSGFFLYMADKQKNGRKKMDDITYKDALIIGSFQAAAIFPAISRSGMTIVAALWRKLDRETAAYFSFLLSTPAIVGAIILQFVDVFQGKAESISSTSLIVGTLSAAFFGYIAVSWMIQYLKRHSLKVFAYYVWGLGILILMLQFTDVF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 3, Bacitracin resistance protein 3, Undecaprenyl pyrophosphate phosphatase 3.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KAP21_CRIFA
Sequence: MLRRTVSNFAMSPYMLFISDLAKTGKLKGIRTPGKFVGKKYRQLSAKEKAALQQRAKQASTPAMTAYRRMAHREMSNKSVPIEQRRANLTKKWNETKQAQREKAQKAQKKTKSAKSKVKKAAKKSKKSKK
What is the function of this protein?
Histone H1-like DNA-binding protein involved in the organization and segregation of kinetoplast DNA (kDNA).  The mitochondrial DNA of kinetoplastid protozoa consists of about 5,000 minicircles and 20 to 30 maxicircles.  These circular DNAs are held together by catenation into a highly organized compact disk structure referred to as a kinetoplast DNA (kDNA) network.  Binds preferentially to a specific fragment of minicircle DNA and is able to compact kDNA networks through DNA charge neutralization and condensation.
What are the official names of this protein?
kinetoplast-associated protein 2-1, Histone H1-like protein p18-1.
What is the protein family that this protein belongs to?
Belongs to the KAP family.
What are the subcellular locations of this protein?
Mitochondrion matrix, kinetoplast.
Protein: Y403_METJA
Sequence: MNKIRYPAVAGLFYPSHPDELIDMIEQCYLHKFGPKSMPVHGTYEKPIGLLCPHAGYVYSGPIQAHSYYELSKRVDALEETTVVILGPNHTGLGSGVSVMDGIWRTPLGDVKCDEEFVEELWRKCEIVDLDETAHLNEHSIEVQLPFLKHLELLNIAKFKIVPICMMFQDYETAVEVGYFIAKIAKELNRRIVVIASSDLTHYEPQEIASKKDAIVIKDILEMNEKELYEDVVNYNISMCGYGPVIAMLKAMKTLGAEKAKLLAYATSGDITGDYSAVVGYASAIVE
What are the official names of this protein?
MEMO1 family protein MJ0403.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: OPGH_CAUVN
Sequence: MSDRSSLFDVRSSTSVTLDQVVRRDTVEIPDEAALAMPVQPLSFWQGGARRATALTQDMNLRRWMLGLMTIAMGVAGWKASFDTIALGGVTRLEAVVLTLLAPLFLALSLWFCTALIGFVVLMGRPKDPLGIDSEAPMPKLHTRTAILMPVYNEDAAAVFARLRAMDASIAETGSARNFDIFVISDTRDAQVALAEQACFARFRREANCNVYYRIRKENTGRKAGNVADWVSRWGSAYEHMLVLDADSLMTGEAMVRLADAMERHPGAGLIQTMPMIINGQTIFARTLQFATRLYGRVAWTGLAWWSGSESSFWGHNAIVRTRAFAETCGLPHLPGPKPFGGEVMSHDALESALLRRGGWSVHLAPYLDGSYEESPSNLLDFATRDRRWCRGNIQHVPLIALPGLHWMSRMHLVIGVLSYALSPLWFFCLSAGLISRALMPELKKAAFTMADLKAAAHALIDWSEIQATAWAMIITFVLLFGPKILGAILVLARKGEVKGFGGKRRMAAGLGVEMLLSALVAPMLMFTQTRAIVEILAGKVGGWAAQRRDADKVDFKEAWAAMGWISLSGLILAASFWFTPDLLTATAPILAGLVLAVPLTMLGAHKVAGLKLKANGLFMTPEERRPPAIVRAAVGAACEPPIRWFARNGRPIGPTTKIRDAA
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFM7_EMENI
Sequence: MADDFDTGDMFKDPEGFYPPEKEPTFAEHRMLSGQVVRVRLVGSHPLYGNMLWNAGRISSEYIETHAPTLIAGKDVLEIGAAAGVPSIVSAIMGARTTVMTDYPDPDLVDNMRQNADASASMIPTDPPSSLHVTGYKWGSDVEPLKAYLPEESRADGFDVLIMADVVYSHREHGNLVKTMQETLKRQKDAVALVIFTPYEPWLLPQTERFFPLAEQGGFTVTKVFEKLTEKLLFENDPGDERLRRTVFGYELRWKDELR
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.
What are the official names of this protein?
Protein N-terminal and lysine N-methyltransferase efm7, Elongation factor methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSAS1_HUMAN
Sequence: MTHPLPHDSHTSGAPPLVNKSRDLANGPPFFSPLQSLWEEFLHLLFMGTLLFYRIATKALRGKATLLKSHSKQPAQPGWEPGIRAPSPVPASSLQDHSRLTSLSRTGKEQRRTLSLIRKTSGTPTESTVATAAASTTEVPSRLPWAARAGFKRTTGVCIALPT
What are the official names of this protein?
Putative uncharacterized protein GSN-AS1, GSN antisense RNA 1, GSN antisense gene protein 1, Protein MOST-2.
Protein: T1SP_ECOLX
Sequence: MSELSYLEKLMDGVEVEWLPLSKVFNLRNGYTPSKTKKEFWANGDIPWFRMDDIRENGRILGSSLQKISSCAVKGGKLFPENSILISTSATIGEHALITVPHLANQRFTCLALKESYADCFDIKFLFYYCFSLAEWCRKNTTMSSFASVDMDGFKKFLIPRPCPDNPEKSLAIQSEIVRILDKFSALTAELTAELTAELSMRKKQYNYYRDQLLSFKEDEVEGKRKTLGEIMKMRAGQHISAHNIIERKEESYIYPCFGGNGIRGYVKEKSHDGEHLLIGRQGALCGNVQRMKGQFYATEHAVVVSVMPGINIDWAFHMLTAMNLNQYASKSAQPGLAVGKLQELKLFVPSIERQIYIAAILDKFDTLTNSITEVSRVKSSCARNSTNIIEICYLVSRSRK
What is the function of this protein?
The specificity (S) subunit of a type I restriction enzyme; this subunit dictates DNA sequence specificity.  The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues of the sequence 5'-CCAN(7)ATGC-3'.  In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site.  Whether the DNA is cut or modified depends on the methylation state of the target sequence.  When the target site is unmodified, the DNA is cut.  When the target site is hemimethylated, the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated.  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage.
What are the official names of this protein?
Type I restriction enzyme EcoprrI specificity subunit, S protein, Type I specificity subunit S.EcoprrI, S.EcoprrI, Type-1 restriction enzyme EcoprrI specificity subunit.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: YNFH_ECOLI
Sequence: MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIVRGMFFLWLLMGVGFIASVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWLVAVIGKMPQALGKLWLLFSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLSGPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVPDYASLQVWRVVLLCAGLGCWLCPLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHMTVGMAIAG
What is the function of this protein?
Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.  The C subunit anchors the other two subunits to the membrane and stabilize the catalytic subunits (By similarity).
What are the official names of this protein?
Anaerobic dimethyl sulfoxide reductase chain YnfH, DMSO reductase anchor subunit YnfH.
What is the protein family that this protein belongs to?
Belongs to the DmsC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AXEA1_PRER2
Sequence: MNRKLFMTGLLMLAMTMQAQTAKKFTLNLSDDGKAQMVCFLPENPSGRAIVGVPGGGYSMLSNTHEGYQASDWLNKQGIAYFVVNYRLPHGDRTIPVGDVEQGFRIVRDSAKVWNINPNDVGIMGFSAGGHLSSVISTMSPYEVRPNFSILFYPVISMDERVSHKWSCINFLGKEGYKDPKLIGQYSTQNAVRSHLTPPACIISANDDRLVPVVTNGIQYYSAMRNAGNECSLFIYPSGDHGFGFGTWFKYHDQLLQDLGNWLKSIPAPKEDAIRVACIGNSITDGFGIDMRAKYGYPAQLQGILGDGYWVKNFGVSARTMLNKGDFPYMNEMAWKDALAFKPDVVVIKLGTNDSKPENWQYGSEFRQDLEQMIKALRPDLAQPAKKGKKKAKAAAQPAGPKILLCTPIPAFKPSWNINDKVITDEIIPIQQEVAKQYGLQIIDLHALMLNDGDKVVDDGIHPNEKGAKKMAEIIAAAIK
What is the function of this protein?
Involved in degradation of plant cell wall polysaccharides.  Is an acetyl esterase with broad substrate specificity, releasing acetic acid from acetylated xylo-oligosaccharides and acetylated xylan as well as xylose-tetraacetate, 4-O-methylumbelliferyl acetate, glucose-pentaacetate, and cephalosporin C.  Appears to have greater activity on oligosaccharides than on polymeric substrates.  Is also able to release acetic acid from xylo-oligosaccharides with 4-O-methylglucuronic acid side groups proximally located to O-acetyl esters.  Preferentially targets xylo-oligosaccharides possessing three or more O-acetyl groups, but following their depletion it is active on the less acetylated portion of the substrate.
What are the official names of this protein?
Acetylxylan esterase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: RODZ_ECODH
Sequence: MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSLGKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDRKAQQEEITTMADQSSAELSSNSEQGQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPAVTAPAPAVDPQQNAVVSPSQANVDTAATPAPTAATTPDGAAPLPTDQAGVTTPVADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQSPAQ
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: RL25_CANAL
Sequence: MAPTTKASAAKKAALKGVNGKKALKVRTSTTFRLPKTLKLTRSPKYQRKSVPHYNRLDAHKIIVAPIATETAMKKVEDGNTLVFQVDIKSNKHQIKSAVKELYDVDALYVNTLIRPNGTKKAYIRLTSDYDALDIANRIGYI
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable).  RPL25 is a major component of the universal docking site for these factors at the polypeptide exit tunnel (By similarity).
What are the official names of this protein?
60S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.