PharMolix/UniProtQA huggingface dataset:
Protein: CO1A2_DOESX
Sequence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
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-2(I) chain, Alpha-2 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: END4_CHLAA
Sequence: MPRFGAHMSISGGVSKSFARGESVGLDSMQIFAKNERQWTAKPISPEEATAFRTEQQRTGIHPVVVHDSYLINLAAPADELREKSIAAFADELERCAQLDIPYLVTHPGAHTGIGEEAGLARVADAICRLLAEGVGGNTMILLETTAGQGTALGYRFEHLARLFELIPYHERLGICVDTCHIFAAGYDIRDPEGYQTTFAELDRLVGLTRVKCFHLNDSQKDLGSRVDRHAHIGQGCIGVEAFRMLVNDPRFADLPMIIETPKGEDMAEDRMNLALLRSLVQGAE
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: LPXH_XYLFM
Sequence: MTTLIISDLHLDPLRPVVTELFLRFLREQVSGADALYILGDLFEVWIGDDMPSEVADMVAAALRTYADAGTPLYFMPGNRDFLVGADYAARAGFRILPDPCVVDLYGEPTLLLHGDLLCTDDIAYQAFRAQTRDPEFIAQFLTQTLSARLAFSQQARLASHAHQSGLKQENDSTQFEKITDVVPADVAAMFACYGVNRMIHGHTHRPALHMLQVAECACTRVVLGDWYQQGSVLCVDADGLVLEQLLLPG
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VRAX_STAAR
Sequence: MIIYRQYQHEGAPVYEIITKTFQHVSIKCDDSFSDTEIFKLLSLLQDDIDHMKVS
What are the official names of this protein?
Protein VraX.
Protein: ACCA_STAAS
Sequence: MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDIEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LC_GOSBA
Sequence: MMLEHIPVLSAYLFSIDIYGLITSRNMVRALMCLELILNAVNINFVTFSDFFDSRQLKGNIFSIFVIAIAAAEAAIGSAIVSSIYRNRKSTRINQSTLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: QUEA_CERS4
Sequence: MQLSDFDFDLPERLIATRPARPRTAARLLLAEGDRIEDRHVRDLVGIFRPGDRLVLNNTRVIPARLTGTRTRGEAEARVEVTLMEPAAAGGWRAMAKPLRKLKPGETIRFSDALSAEVAEKGETDLRLVFDRAGAAFDAALAEAGAMPLPPYIAARRAPDTQDDEDYQTVFARHAGAVAAPTASLHFDRPLLEALAARGVGFTEVTLHVGAGTFLPVKVEDVTTHRMHAEWGEVTETAAAEIAATKAAGGRVIPVGTTALRLIESAAASGAIRPWRGETDIFIYPGYRFRVTDALMTNFHLPKSTLLMLVSALMGQERIRAIYDHAVRHDYRFFSYGDASLLIPGG
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP25_ASPNC
Sequence: MNRALLRAAWSSGTALRAPPSVSRAAVYRSAIHPVNRSFASVSCLQSEQPSSSSSAVPPALEPKDELTGNSTSESTPHIPWYLQEEAPLAESEQTFSRDQIPELPTNPPAILPALLDYVFKDIGLDALKLIDLRGLETPPALGANVIMIIGTARSVKHLNVSADRLCRWLRSTYKLSPYADGLLGRNELKIKLRRKARRARLASRSGTMFDEKDDGITTGWICVNAGVVEETPVKKDESYSFEGFGHTATGTRVVVQIFTEEKRAEVDLESLWQKALDRSEREKQRLSQVNPGAPSEEVRASNSINVSPSDREFGHASRFPTSPLFGQKRLLHTDHRPISQKFDRAAIHAEDTEEALGSQSSSLLRDHDHSDNEKKLRSMDALFDHLSNLSDVQARIELGEGPEDHDSTLFLRLFHDVLSVSSAEEKAIARLVLFCNAISRQHPGYTKRGLYAAFTECTCAGYLVSDDLAFSVVSALLSPRLAGTSSEDVAGQVPEADQELALLVLEHLSLRGTNVVNMRVFDMIYRAVAISPSTTAPDGANDAQTGNKSSLYRVTRLIDTLDLPFEPEQARSLMLSLFQHGDYDDFWKLWRKGPLNGSLRTAADYKMLFRLHADLGDELRARDCVSTWIPMMRREDNPIPLEGELLVDIKRCLMLADPDIVQKAAEGSTSNLARFWNACQMKMLR
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: LYS4_CANGA
Sequence: MVVLRRSFHVYTRLQRGQNLTEKIVQQYSVGLAPGKRVHSGDYVSIKPAHVMSHDNSWPVALKFMNLGARTVKDPRQIVNTLDHDIQNKSDKNLTKYRNIESFAKKHGIDFYPAGRGIGHQIMVEEGYAFPLNLTVASDSHSNTYGGMGALGTPVVRTDAAAIWATGQTWWQIPPVAQVEFKGKLHESVSGKDIIVALCGVFNKDQVLNHAIEFTGDAIKHLPVDFRLTIANMTTEWGALSGLFPVDDTLINWYKNRLNIVGPNHPRINETTIKNLEDKAKVFKADSDAVYAKKLVIDLSTLTHYVSGPNSVKVSNTVQDLARDNIKINKAYLVSCTNARLSDLESAAKVVCPTGDLSKVNKVADGVEFYFAAASSEIEKEAAEKGIWQALLAAGCKPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGRIGSPAEVWGIEDVKSSGLLAEELACNTETSTATPVSEGSAAKVEMLEGFPEEIVGELVLCDADNVNTDGIYPGKYTYQDDVSRETMAQVCMENYDGEFGSKANAGDILVSGFNFGTGSSREQAATSLLAKGINLVVAGSFSNTFSRNSINNALLTLEIPTLVEKLRSKFENAPKELTRRTGWFLKWDVPNAKVYVTEGSPDGQVLLEQKVGELGKNLQEIIIKGGLEGWVKSQL
What is the function of this protein?
Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
What are the official names of this protein?
Homoaconitase, mitochondrial, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GLK_AGRVS
Sequence: MPKPHDNDHMPFPVLVGDIGGTNARFWILMDAHAAPKEFANIHTADFPTIDQAIQDCILDKSGFQPRSAILAVAGPIKDDEIPLTNCPWVIRPKAMIADLGFDDVLVVNDFEAQALAAASLGRNDREPIGPLTETSLNSRVILGPGTGLGVGGLLYTHHTWFPVPGEGGHVDIGPRSDRDWQIFPHIERIEGRISGEQILCGRGILHLYNAICAADGIEPVWTDPADVTQHALKGNDPVCVETMTLFVTYLGRIAGDMALVFMARGGVFLSGGISQKIIPLLKSPVFRAAFEDKAPHTEMMKTIPTFVAIHPQAALSGLAAYARTPSSYGVKHEGRRWQR
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_BORBR
Sequence: MYKIGLTGGIGSGKSRVADMLAEWGASVIDADEISHALTAPGGAAMPAIAREFGPQAVAADGALDRAWMRDLVFREPAARGRLEALLHPLIGLHTEQAAAQARGLYLVFVVPLLVESGRWRGRVDRICVVDCDPATQIARVQKRSGLTEPAIRRIMAAQAARATRLEAADDVIVNDGATSPDTLRARARTLHDRWLALAGAASQPGGKAAGTPE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYT1_ARATH
Sequence: MRDYIPKYLNAFLLAFATFAVGFAIFIAKDSNSSSHLYFSTSSSLWTSSFSPAFITVSIFLTVHRFREKRKRNGSNPGSGYWKRDGKVEAELATARVLIREAQLNYSSTTSSPLGDEDYVPHGDIYRNPYAFHRSYLLMEKMFKIYVYEEGDPPIFHYGLCKDIYSMEGLFLNFMENDVLKYRTRDPDKAHVYFLPFSVVMILHHLFDPVVRDKAVLERVIADYVQIISKKYPYWNTSDGFDHFMLSCHDWGHRATWYVKKLFFNSIRVLCNANISEYFNPEKDAPFPEINLLTGDINNLTGGLDPISRTTLAFFAGKSHGKIRPVLLNHWKEKDKDILVYENLPDGLDYTEMMRKSRFCICPSGHEVASPRVPEAIYSGCVPVLISENYVLPFSDVLNWEKFSVSVSVKEIPELKRILMDIPEERYMRLYEGVKKVKRHILVNDPPKRYDVFNMIIHSIWLRRLNVKLL
What is the function of this protein?
May be involved in cell wall biosynthesis.
What are the official names of this protein?
Probable glycosyltransferase At3g07620.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: Y626_PELPD
Sequence: MKHIIHFDCFAGISGDMTVAALLDLGVPLEHLRDELARLDLPRDSYSLSIHRTERRHLAALRFDVQVLDQRTERGYAAIDGLIAASSLSGPVRERARAIFRRLAEAEALVHGVAVGEVHFHEVGAVDSIVDIVGTAICLDYLGVDGLSAAPLPLGSGFVHTAHGVLPVPAPATAELLKGMAVHGECGPGERVTPTGAAILAALATSVTAQPAMTVTAVGSGAGSRDFPDVPNILRAFLGRPEGEMSDGVLVAETNIDDSTPELLGYVMELLLEAGALDVFFTPIQMKKNRPGVQLSFLCRSGLLERLAALVLVETSAIGIRHYPVSRTTLERCMEERETPFGPLPFKLLFHDGRPLRAAPEYEACRRVARERGIPLQEVIRIVSQPTVVEGG
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: DLTC_ENTFA
Sequence: MNIQETVLNILEDITGTDEVVNNQDIQLFEEGLLDSLATVQLLVEIEGQLGIQVPVSDFDREVWGTPKQIIQQVEALQ
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXD_PHOPO
Sequence: MKSENNSVPIDHVIKVDNERHIRVWETFPKNQCDKRNNTIVIASGFARRMDHFAGLAEYLSTNGFHVIRYDSLNHVGLSSGEIDQFSMSVGKKSLLTVIDWLKSEHGIDQVGLIASSLSARIAYDIVADVNLSFLITAVGVVNLRNTLEQALKYDYLQMEIDEIPEDLDFDGYNLGSKVFVTDCFENNWDTLDSTINKTKNLNVPFIAFVANDDSWVQQHEVEELMSNINSDKTKIYSLIGSSHDLGENLIVLRNFYQSITKAAIALDSNLVGLVSEIIEPQFEALTIATVNERRLKNKIQSKSLA
What is the function of this protein?
Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction.
What are the official names of this protein?
Acyl transferase, ACT, C14ACP-TE, Myristoyl-ACP-specific thioesterase.
What is the protein family that this protein belongs to?
Belongs to the LuxD family.
Protein: DABA_STAAE
Sequence: MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYIDNIKTLKDVPASYMNHSNVDVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTHFSIDQEDYQAYVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAIRLVVEQLLVGDEFKSVAKDCESRSENWFKQTVASWCYYSDMPSDVLLQHDVNEIQTFIHFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGALDVNQVNVSENDNANQPHSVLLNDTQAVDENNSELNQMGTSTKAQIAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDREFDRTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQSGVYIPETTVFAVAEHHTSTDTLAWVYVPDTLSSIALDAYESLNDAMPMISEHANRERLDKLPTIGRVNHPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGTLLNTIISGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRTMYHSPIRLLVVIQAPDYVVARLLANNEHFARKVSNHWLRLMSVNEEGRFKSWI
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PX111_ORYSJ
Sequence: MSTLDATRAELGLVVLYLNKAEARDKICRAIQYGSKFISNGQPGTAQDVDRSTTLARKVFRLLKWVNDLHGLISPPAKGTPLTLVLLGKSKNALLSTFLFLDQFVWLGRTGIYKNKERTDRIVRISLYCWMASSVCAGLVELGELKRLSKSMRKLARELRDTDKYENDQYKSKMKQSDERLLALVKAAMDVVVAVGLLQLSPKKITPRVTGAFGFVTSLISCYQQLPSRAPAIKVKA
What is the function of this protein?
Involved in peroxisomal proliferation.
What are the official names of this protein?
Peroxisomal membrane protein 11-1, OsPEX11-1, Peroxin-11-1.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: RSMH_SACD2
Sequence: MNESPHFSVLLQESVESLVVDPAGTYVDGTFGRGGHSRAILAKLGPEGKLFGIDKDPEAVAVGKALEAEDSRFRIVHGSFADLKHIDLLQADFAAGGLSGVLVDLGVSSPQLDVAERGFSFMNDGPLDMRMNTEAGMTAAEWINTAKQEDIAQVLWEYGEERFSRHMAKAIVERREIKPFTRTHDFAEVVKAANRKWEKGKHPATRAFQAVRIFINRELEDLRQLLDDSVSVLAPGGRFVVISFHSLEDRMVKRFFRDQSMGKQFPKGLPVTEEMKKQNLKIIGKALKAGDTELTQNIRSRSAVMRVGERLG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_THEVB
Sequence: MRELTLTTTVFQTTKSQEIFAAAQKLMPGGVSSPVRAFKSVGGQPIVFDHVKGAHIWDVDGNQYIDYVGSWGPAIVGHAHPEVIDALHAALEKGTSFGAPCLLENILAEMVIAAVPSVEMVRFVNSGTEACMAVLRLMRAYTQREKVIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPKATTAATLTAPYNDLEAVSRLFEQYPNDIAGVILEPVVGNAGFIPPDAGFLEGLRELTKQYGALLVFDEVMTGFRIAYGGAQEKFGVTPDLTTLGKVIGGGLPVGAYGGRAEIMKMVAPAGPVYQAGTLSGNPLAMTAGIKTLEILSRPGSYEHLDRITGKLVQGLLDAAREFGHEVCGGHISGMFGLFFTAGPVTNYEQAKQSDLKKFAAFHRGMLEQGIYLAPSQFEAGFTSLAHTEADIERTIAAARTVLSQL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_STAES
Sequence: MAKNIAKALLDIEAVSLSPNDLFTWSSGIKSPIYCDNRITLGYPEVRNAIRDGLIQLIKEHFSNVEIISGTATAGIPHAAYISEKLELPMNYVRSKSKSHGKQNQIEGAKSENKNVVVVEDLISTGGSSITAVEALEEAGANVLGVVAIFTYGLAKADKTFNKAHIPFYTLSDYNELIEVAKDEGKISLNDIQTLVDWRDNLS
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: ECO1_CANGA
Sequence: MAVNHVRSKSSNGKRLVQSKLNINNETILKCPKCEMKYSPNSIDDVATHKKYHDLHINGRNWSQTWGIPIHDTTSSTIIATPSSSPFKTGKSVNNKNNERIVMIQENKPAEVKAMLEIMDIVNQELNAPQDENNFWRKPNAEHQGKAIVYIKDKKVVGAITVEVLKQHKCRWMIYETRTLVEHVRPQFTLGISRIWVCRAQRGKGIAEKLLDAARISAIPGQNVDKMKLAWSQPSDSGGKLAKKYNGVKHKSGHILIPCYL
What is the function of this protein?
Probable acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together.  In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase.  Acts by acetylating the cohesin complex component SMC3 (By similarity).
What are the official names of this protein?
N-acetyltransferase ECO1, Establishment of cohesion protein 1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ECO subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZBT22_MOUSE
Sequence: MEPSALSPSGATLPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRSAATTTTVTTAAAPSVSVPCASVPSGNGGTVAPATVGSVRSHTSSRASENQSPSSSNYFSPRESTDFSSTSQDAFVASAAGSGNRRDGGPVFPAPVVGSAGTTSGKLLLEADELCDDGGDGRGAVAPGAGLRRSNCMPASAVPQKHWVYVKQARNCPAPASLVHQDPDLEDEEEEEDLVLTCEDDEDEEMGGGSGVPAGGEPEATLSISDVRTLTEPADKGEEQVNFCESSNDFGPYEGGGAGAGLDDPGGPTPSSYALTHPPRPLLPLDVPGNQILVFPSSSSQAPGQPPGNTAEHGAVTLGGTSAVGLGIPSGSGGAPGGTGNSDGNKIFLCHCGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECSVCAKKFMWRDSFMRHRGHCERRHRMGVGGVGSGPGPGPGPGTPSGPALQPKRESSTVGGGSGDEANSATPPSHRRVWSPPSVHKVEMDFSGGGGAAH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 22, Protein BING1, Zinc finger protein 297.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASSY_SYNY3
Sequence: MGRAKKVVLAYSGGVDTSVCIPYLMHEWGVEEVITLAADLGQGDELGPIQEKALRCGAVESLVIDGKEEFVKEYAFRSIQANALYENRYPLSTALARPLIAKMLVEAAEKYGADAVAHGCTGKGNDQVRFDISIMALNPNLKVLAPAREWKMSREETIAYGERYGVESPVKKSSPYSIDRNILGRSIEAGPLEDPMTEPTEEIYLMTKAIADTPDEPEYVDIGFEKGIPVSLNGVMLDPVTLVERLNEIAGNHGVGRLDMVENRVVGIKSREIYEAPALLVLIDAHRDLESLTQTADVTHYKNTVEEIYSQLIYRGLWYSPLKEALDAFIVKTQERVTGMVRVKFFKGNANVAGRKSDYSIYDAELATYGMEDQFDHKAAEGFIYIWGLPTKVWAQKMRG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_AQUAE
Sequence: MENLNIVTLTGAGISAESGIPTFRGKDGLWNKFKPEELATPEAFFRNPKLVWEWYDWKRQLIAKAQPNEGHKILTKMEEEFPNFYLITQNVDGLHQRAGSKKVIELHGNIWKVRCVECGNERYEYTTPLPEIPPKCEKCGGLLRPGVVWFGESLPVDALSRAYELSREAHVFIVVGTSGVVYPAAELPFVAKENGAQVIEVNPEETPITKIADMHFKEKASTGLKKVYDYLREKYGSKG
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TALD3_MOUSE
Sequence: MKNVEFSLERGQRLKMPARKLREIVSPNQGNKLAVVEDELPRVPPALAANKRLAVETRTSSNGTLCGSLDLTSARLYHQPLLESPPASKKSDFSKDAVVRQLPLNKTEENNAPKANDIFISQYTMGQKDALRTVLKQKAQSMPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIKVQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDAALKASSLQLGMSTSRAVGKYSGKLGSPSVGSSVFSHNTFVSKRVPLSEDTDFDGQKSPLETPAPRRFAPVPVSRDGKITKRESPTEEKENMEMNSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERGTAQVPVPKYNDVVHDLGQKKQASDMLQIKQSPVTLRLSDHPHNPALLQTTNTRSVLKDAAKILRGVQNNKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEIQDELMRKDYEQKRFDPKNQRNKKALTMSRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQKERSGLLKSATTLQDEDYMLQIYGKPVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASRMKMDSKIQHPITALPHADQQYMVSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPASRKGNAGVKKPNVAIVEMKSEKKDPPQLSVQILPSVDIDSVSYSSTDGASSPPSPKEASLPPLHTWIQTPDFMKVDEEEVPLPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQWVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVMLADREAERQRAAATSVPGDLSGTETNLLARVCAPVATPQPTPPCSPSPVREHVRVKTPDSSPCESDPDAASSIKEIRVEKGSDMPAVMLVSTPTRTPVATPPPAAALTPTLSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVANEEPESVDFSAQPAPPEPAPSAPLPEGTKAPSLQRVPSSGSSTLENTLSTVTETETLDRHISEGEILFSCGQNLATKRPGDLFLMNINDSLSSTLQDALEMEDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQEEDLDNSVGELSEGQRLVLKAAEDISAGPSGQMLPPTSPAEPSYQHADPRLVLQQSDMASGNICEDLCASHGPMSLRELELQPDSNLILPITHTTTAVSDGNLPEAAEDFSQYQQKQDSDIKQVEHKPIQRHLTSVRNKPDSTLSQHQGGPADLLLIAHVSPARMSVTLPSANLEDCSQSLSTSSMHGGTESSGTDTF
What is the function of this protein?
Required for ciliogenesis and sonic hedgehog/SHH signaling (PubMed:21750036).  Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1.  May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation (By similarity).  Involved in regulation of cell intracellular organization (PubMed:26386247).  Involved in regulation of cell polarity (By similarity).  Required for asymmetrical localization of CEP120 to daughter centrioles (PubMed:25251415).
What are the official names of this protein?
Protein TALPID3.
What is the protein family that this protein belongs to?
Belongs to the TALPID3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Photoreceptor inner segment. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=In photoreceptor cells localized to the joint between the inner and outer segments, specifically localized at the mother centriole (basal body) and the adjacent centriole as well as between the two centrioles but not in the connecting cilium (PubMed:26386247).
Protein: PURA_COXB1
Sequence: MNIVILGTQWGDEGKGKIVDMLTEDVAAVVRFQGGHNAGHTLIIDGEKTILRLIPSGILREGVLCLIGNGVVLSPPALMEEIEELNAKGIPVTERLRISSACNLLLPYHVALDKAREAELGTKAIGTTGRGIGPAYEDKVARRGIRAMDLLHPDQLLEKIKKATAYHNIQLEHYYHQTPLDYQSIYNQLMEFREKIKPMIGDVSALLGNLRRQNKHIIFEGAQGSLLDIDLGTYPYVTSSNTTAGSAATGSGFGPLYFDRVLGITKAYVTRVGAGPFPTELTNEEGKKMAKRGNEFGSVTGRPRRCGWFDVISMRRTIQINSLTGIVLTKLDVLDEFAKIHLCTAYRCDGEVVNEPPFDQSLLESCEPVYEEMPGWQTSTYGLTDYSEMPKEARNYISRLEELLGVPITIISTGPDRKHTIVRQAVFNQVITAKG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.