PharMolix/UniProtQA huggingface dataset:
Protein: CO1A2_MYLDA
Sequence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
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-2(I) chain, Alpha-2 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: PYRF_HALLT
Sequence: MSFFETLADRIEATDSVVSVGLDPDPNRLPEFLANADLPRWAFNRRIIDATHEHAACYKPNAAFYEDADGWRALEETIAYAHGKDVPVLLDAKRADIGNTTRQYAAALDRADAITVNPYLGRDSLQPFLDREEKGVFVLCRTSNPGGSDLQDLELASGEPLYERVAALADVWNGNDNVGLVVGATAPEELAEVREIVPEIPFLVPGVGAQGGDAEAAVEHGLADRPDAAVDVGLVNSSRGIIFAGEESSRPDDEATYFGAAGDAAKRLKKRLNQYR
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: RS17_SYNJB
Sequence: MAVREKIGIVVSNKMQKTVVVAVENRVAHPKYGKIVVKTKKFKAHDEENRCQEGDLVRITETRPLSRTKRWQVAEILREVKKL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: VQ4_ARATH
Sequence: MENSPRYREATNLIPSPRCHNSNNSCGMSSSSESNKPPTTPTRHVTTRSESGNPYPTTFVQADTSSFKQVVQMLTGSAERPKHGSSLKPNPTHHQPDPRSTPSSFSIPPIKAVPNKKQSSSSASGFRLYERRNSMKNLKINPLNPVFNPVNSAFSPRKPEILSPSILDFPSLVLSPVTPLIPDPFDRSGSSNQSPNELAAEEKAMKERGFYLHPSPATTPMDPEPRLLPLFPVTSPRVSGSSSASTS
What is the function of this protein?
Acts as negative regulator of WRKY33 transcription factor activity in the promotion of defense gene expression.  Acts as a negative regulator of pathogen-associated molecular pattern (PAMP)-induced responses to modulate resistance to pathogens.
What are the official names of this protein?
VQ motif-containing protein 4, AtVQ4, MPK3/6-targeted VQ-motif-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS7_CHLPD
Sequence: MPKQNKYKGVSVDYRYGDESVARFINAVMLDGKKDVATRIVYDAFTIIAEKMNGESPLEVYRKAMSNIAPVVEVRSKRVGGATYQIPMEVKPSRRGALAFRWLKLYAKRRGGRSMAEKLAAELMDAANEQGASVKKRDEVHRMADANKAFAHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: METL2_MOUSE
Sequence: MAASFPEGVPETEDGKRPQFGHRFLSDPARVFHHNAWDNVKWSEEQAAAAERKVQENSSPLVCPEKQVDYEVNAHKYWDDFYRIHENGFFKDRHWLFTEFPELAPSHSHLTGVPLEKQRSDVCEDGPGLTAEQHKCSCASPGCETQVPPLEEPVTQKLGHLEISGEEFPGSSATYRILEVGCGVGNTVFPILQTNNNPNLFVYCCDFSATAIELLKTNSQYDPSRCYAFVHDLCDEDQSYPVPEDSLDVIVLIFVLSAIVPDKMQKAISKLSRLLKPGGVMLLRDYGRYDMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQGELDTLFTAAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQCKYSKPLALRSSQHVPIPHATESSSHSGLL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU) (PubMed:28655767).  N(3)-methylcytidine methylation by METTL2 requires the N6-threonylcarbamoylation of tRNA (t6A37) by the EKC/KEOPS complex as prerequisite (By similarity).
What are the official names of this protein?
tRNA N(3)-methylcytidine methyltransferase METTL2, Methyltransferase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFA_ALIF1
Sequence: MTEYLLLLIGTVLVNNFVLVKFLGLCPFMGVSKKLESAIGMGLATTFVLTLASVCSYLVETYILSPLGIEYLRTMSFILVIAVVVQFTEMVVHKTSPTLYRVLGIFLPLITTNCAVLGVALLNVTENHNFVESIIYGFGAAVGFSLVLILFSAMRERIAAADVPLPFKGASIAMITAGLMSLAFMGFTGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TEV1_BPT4
Sequence: MKSGIYQIKNTLNNKVYVGSAKDFEKRWKRHFKDLEKGCHSSIKLQRSFNKHGNVFECSILEEIPYEKDLIIERENFWIKELNSKINGYNIADATFGDTCSTHPLKEEIIKKRSETVKAKMLKLGPDGRKALYSKPGSKNGRWNPETHKFCKCGVRIQTSAYTCSKCRNRSGENNSFFNHKHSDITKSKISEKMKGKKPSNIKKISCDGVIFDCAADAARHFKISSGLVTYRVKSDKWNWFYINA
What is the function of this protein?
This endonuclease is specific to the thymidylate synthase (td) gene splice junction and is involved in intron homing.
What are the official names of this protein?
Intron-associated endonuclease 1, I-TevI, IRF protein.
What is the protein family that this protein belongs to?
To endonucleases of group I introns of fungi and phage.
Protein: PUR7_AERS4
Sequence: MSLADQVLAVNDDLPIRTDKPVHSGKVRSVYWLTPEDSARLIKEKGYDVPADAPLALMVISDRISAFDCIWQGVDGLNGVPGKGAALNAISSHWFKLFKEKGLADSHILDIPHPFVWIVQKARPVMIEAIARQYITGSMWRAYKDGEREFCGITLPEGLKKDQKLPEILITPSTKGVLTGLDGVPEADDVNVSRADIERHYQGFNFSKPADIDRYEVLLKEGFNVISDALASLDQIFVDTKFEFGYVQDAAGNEKLIYMDEVGTPDSSRIWDGAALRDGQIVEKSKEGFRQWLLNHFPDPDILLNKNRMPERFALAKGNKLPTEVMMDISNTYVGIAEKIIGHPLVRSANPKQEIIEVLRDQYGLID
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MILK1_HUMAN
Sequence: MAGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAPCSPPSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAPGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGREDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMKMLKLLGNKRDAKSKSPRDKS
What is the function of this protein?
Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes.  On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation.  May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking.  Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane.  May indirectly play a role in neurite outgrowth.
What are the official names of this protein?
MICAL-like protein 1, Molecule interacting with Rab13, MIRab13.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein. Late endosome membrane. Note=Localization to late endosomes is actin-dependent. Association to tubular recycling endosomes is regulated by RAB35 and ARF6.
Protein: RBM43_RAT
Sequence: MASALTVKDPTVSERTVVVSGLPVGLSKDQLVKRYFRDEGGHVEKVIYPPRSKGVAYIIFKEKKVAQTIIRQKKHSLGSEPLLTVSHFSEKVFNYVMAILDLSVFRPQIVLESLVVDLKKKIPTLNFSPLGRSGKISVQGSFLAILKLKQALISKAISALENNRKYAGERRNWTGQNPRRVLQKNENSAPTLGTSVPEPAGSPETLVLDTDVFLYLKHKCQFYEPTLSKYHVLCQERVDGDITTLCLQDARDGSYPGSVRHVKELIEEWAQEFYLELRKELLVLEGRRESEKRNMRQAFEQLCCRYPRVLMNVHRTHIDLIGPPSDTSLFKTQLMKSAGQKVT
What are the official names of this protein?
RNA-binding protein 43, RNA-binding motif protein 43.
Protein: SPDB_STRLI
Sequence: MEKKRSMTAAPAVAMTAVSMVLTVVVIVMWLGEAMPWAVALVVGLGLDGGWLATLAYERRLAARGDHSRAITGVGWGFGAVATGVLVAHALGEESAGAWLAVAWLPLAAKALWLVHGLWERTALTPTALDQIRDIQQDARDRAAVARAQLRAEAGTEVTRLEAVTGAGARVARVQAETAGELASAWSTLEEAREGEGTARALTCVTSRVTPTSPPSWRLPVWGPTEPVPAAIEGSADVVPLSNEEIDGIMSGLVDSGSYRVAAGRFRDMGYSAGEARLQASWRRVTREVAA
What is the function of this protein?
Involved in plasmid transfer.
What are the official names of this protein?
Protein SpdB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCA3C_PHATC
Sequence: MGFLRRQLREQFEKKKPEALQADIRMISGCQDVQTSADVSNVSSFQLPDPAGNAGGACTSTLLNVLYKDHQTPEDTMSFVELLNKMRENLEAKGFSQVPQLTASHPIDVNDDFDLVPPAATGTRRALLIGINYVGHEQGVLRGCHNDVKNMVEYIKAVHGFEDENITILMDDGEHTAPTHANMIAAYKKIVALSKADDALFCHFSGHGAKIRDDDRGEEDDGYDETLVPIDYHENGMIRDDDLYDILIKPLVQGVHLVCLMDCCHSGTVLDLPYVYKADGNFTEMEIDENFDFKKLLGKFGIDDFDKFGGEALGKINGDALGKVGKDALGKLNKFFG
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine residues.
What are the official names of this protein?
Metacaspase III c, PtMCA-IIIc.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: SYD_SALCH
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDAKNVNADMATGEIEVLASSLTIINRADSLPLDANHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVEISFMTALQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELVDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGAQLSRKQIDDYGNFVKIYGAKGLAYIKVNERAKGLDGINSPVAKFLTADIVDAILERTGAQDGDMIFFGADNKKVVADALGALRLKLGKDLSLTDEDKWAPLWVIDFPMFEDDGEGGLTAMHHPFTAPRDMTASELKTAPEEAVANAYDMVINGYEVGGGSVRIHNGEMQQTVFGILGINEQEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANQAALTELGIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y969_TREPA
Sequence: MKVLLRVLLSPWGCAVYRTGGGVVSAGMKVLVYAVALGFGCGGVVHMREGDTYQQLLEHRIANGREFSRVFAQAQVDEAEHNEVRTKTAGSVQIGTGDVLFNKKNGNGANGYKVEMAPHLSIASPFIGNSRLNLVAPRKLDGVTSTSTVSVDYTTDFYSSVRPTYLNSLKEKTYQKEKSGSALRDGRRLVEREFLQEVQRLYGSYADQVRASLELVRARLRFESVKRQGYQEDSAYFQSAQLAQVRAERARAQARQRFDLEYTRFAARNGVAYEDDERDGFLHDLAVAVPLEPAMAVTQCAGERGREYCDAQDRCERVIAQRGTDYSPFRTSARVYFTDGEENKQLTNGMAPAAPSTTSTYGGTFNMAFPGGDSSFTVQNSKGLAGILANFEWSPIRTRYRSLDYTAERAERVFDEVELQAKGDRSNKLFGAIDAQGDSVLVLRGVDLQTLDNARKKARLQKERLERGIIGRLEYEAARSEYLLALASVAEAKARAIIFNTDLACAYGVGADAAAAQLTQEEMVVSEKKDAEEKKERSS
What are the official names of this protein?
Uncharacterized protein TP_0969.
What is the protein family that this protein belongs to?
Belongs to the TP096X family.
Protein: MDH_RICRS
Sequence: MKQHPKISLIGSGNIGGTLAHLISLRELGNIVLFDVTEGVPQGKALDLMQAVTIAGSDIKIKGTNDYKDIKGSDAIIITAGLPRKPGMSRDDLISINTGIMKTVAANVKKYAPDAFVIVITNPLDVMVYVMLKESGLPHNKVIGMAGVLDSSRFNLFLAEEFKVSVSNVNSMVLGGHGDAMVPLARYSTISGVPIPDLIKMGLSSNENIEKIIDRTRNGGGEIVALLKTGSAYYAPAASAIEMLESYLKDKRQILTCAAYLQGEYGVHDLYVGVPIMIGKEGVLKVIELQLTTEEKALFDKSVEGVKKLIETIK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: NADK_PEDPA
Sequence: MRVAIYHSSDEHSIQVGKDLAKILSQNEIVIDNEKPTVVITIGGDGTLLSAVQKYLNLLEEVRFVGVHTGHLGFYTDWREYELETLVKALKSDGGAEVSYPLLNIDVTHTDGSHISYKAVNESTLRKLSGTMVADVLIGDNLFERFRGDGLCISTPTGSTAYNRSVGGAIVHPRLEVLQMAEIASINNRVFRTVGASLIMAPNETITIRPVPSFHRTYNFTADRIDLLDKHVKEVHYSIDEQKVKFLKYRHTGFWNRVRNSFIGSIDEV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_CHESB
Sequence: MLTRKQHELLLFIHARLKETGIPPSFDEMKEALDLASKSGIHRLITALEERGFIRRLPNRARALEVLRLPDSIAPGLAAPRKFSPSVIEGGQGRSSPAPRPAANNDDETSVVSIPVMGRIAAGVPIDAIQHRTHSIGVPPDMITGGEHYALEVKGDSMIEAGIFDGDTVIIRQTQAANPGDIVVALVDEEEATLKRFRRKGASIALEAANPAYETRIFGPDRVKVQGRLVGLIRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: Y2432_MYCLE
Sequence: MRPVIKVGLSTASVYPLRAEAAFEYAAKLGYDGVELMVWGESVSQDIDAVKGLSRRYRVPVLSVHAPCLLISQRVWGANPVPKLERSVRAAEQLGAQTVVVHPPFRWQRRYAEGFSDQVAELEAASDVMIAVENMFPFRADRFFGADQSRERMRKRGGGPGPAISVFAPSFDPLAGNHAHYTLDLSHTATAGSDSLEMVRRMGSGLVHLHLCDGSGLPADEHLVPGRGTQPTAAVCQLLAGADFAGHVVLEVSTSSVRSATERETMLTESLQFARTYLLR
What are the official names of this protein?
Uncharacterized protein ML2432.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv0498 and S.coelicolor SCO3347.
Protein: Y2825_STUS1
Sequence: MHQRIDNTFEFGRFLVRRFMADQGPQSAAALTYTTLFAVVPMMTVTFAMLSAIPAFKGVGEQIQFYIFNNFIPSTGATIQEYLLAFTSQARQLTWFGVGFLMATALMMLLTIEKAFNTIWRVRQPRRGVSSFLLYWAILSLGPLLLGAGFATSTYIASLSLISGPYALIGVGTLIKVMPLLLSVAAFTLIYAAVPNTRVPLRHALVGGVFTAVLFEAAKQMFGVYVSYFPSYQLIYGAFAAVPLFLLWIYLSWMIVLFGAELVCGLSSSQQWRRRPLPRLLVMLMLLRNLHERQQEGRELHLRDLHKAGLRLPEDEWDDILGFFEQEQLVCRTGSGGWVLCRDLNHYSLDQLLRCNPWPLSARVELPEQLNEPWYPTLRRSLELLQQEQANLFGGSLADWLQANGDKKRQ
What are the official names of this protein?
UPF0761 membrane protein PST_2825.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
Protein: RL2_AZOPC
Sequence: MGIRKLKPVTPGQRHRIVGMFSEITATIPEKSLVFGKCKSGGRNAEGHRTVRHIGGGHKRRFRLIDFKRNKDGIPARVKSIEYDPNRSARIALLYYADGEKVYIVAPNGLKVNQLIVSGKEAPPEVGNSLPLADIPLGTIIHNIELRPGQGAKMVRSAGVFAQVVSREGNYVIVRMPSGETRKVLALCRASIGSVSNSEHALEKSGKAGRIRWLGHCPHVRGVAMNPVDHPMGGGEGRASGGHPRSRKGLYAKGLKTRNLKKYSSRYIIESKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: DESI1_MOUSE
Sequence: MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSSGISSCTPGGTLLGPPDSVVDVGNTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLSTPFGQALRPFLDSIQIQPPGGNSVGRPNGQS
What is the function of this protein?
Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins (PubMed:22370726, PubMed:22498933).  Has isopeptidase but not SUMO-processing activity (PubMed:22370726, PubMed:22498933).  Desumoylates ZBTB46 (PubMed:22370726).  Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (By similarity).
What are the official names of this protein?
Desumoylating isopeptidase 1, DeSI-1, PPPDE peptidase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the DeSI family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm; exported from the nucleus in a XPO1/CRM1-dependent manner via its nuclear export signal motifs.
Protein: PDXY_PSEPW
Sequence: MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRIGVNVWPLNTVQFSNHTQYGQWAGEVLAPAQIPALVEGISNIGELGHCDAVLSGYLGSAEQGRAILAGVERIKAVNPKALYLCDPVMGHAEKGCIVPQEVSEFLLDDAVAQADILCPNQLELDSFCGRRAQSLEDCVRMARGLLERGPQVVLVKHLAYPGRCEDMFEMLLVTRDHSWHLRRPLLAFPRQPVGVGDLTSGLFLARVLLGDSWVQAFEYTAAAVHEVLLETQACASYELQLVRAQDRIAYPRVRFEAQRLAF
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: UNC36_CAEEL
Sequence: MRVVHLLVVLATYVSTTSSFNKESIKECAKVLSEHMKETFSKISHETILKQNYEKLVEEEQFDPRAELKKSKHRIEDYLKVRSQFAYKAKISLEARSVRNDSTVNDPQSKSFIRFMSAKQGNDGTTIYESNHLGKRLKVNETKSFNLTQNANFYTLPTSSVSSAVHIPTPLYDRNEDLLRKIDWSDIDAVYRTNREETKDLAFQLFCSEAGYMRYYPAASWFWDNQDEHLDLFDCRNTEWYINSATNSKNVLIMLDMSGSMLGQRYEVAKQTTEAILETLSHNDYFNIMTFSKNTFLLDGCNGTNGLLQATMRNKKALRRKMDTYQSEGKAEYEKALPLAFSVLLDLKGSYALYTKEEMSMMSANATNEYQFHLELPEHVLAATKQYIDSINNGGGDNNRGACENVIMLITDGAPNAYKKIFDMYNADKKVRVFTFLVGDEAIDFNEVREMACNNRGYMVHVANMADVDEKIHHYIRRMSRVVGRHYKESGQLSWWTGVYRERLYLPRPEIFAEPVPITNQSFAVMNKMASRRKIRLQKSEARSRMFVTTVSYPVIVNETFMGVAAVNIPLTEVAQKSHPANIGSKSYFFMLDQNGFVMTHPQLRPIDPFTKYHKQNYNNMDLLELEVGQNQNVRSSQKSQAVSDLVCESGANYAECVDDLRKAVRKMIIDCDNSDVQQLDVLYATELLDRVYPQTNTYYAECINHANFVLGLAVAKGDDYRVVKKQKKYDFGRVKMDWMGDKRWRLHPHWRYCFLNDTDTHMSKEEAFEIYAQQMSDSGKAPLLCEYRRNLVEKLLLDMEATSNLIDSWDTQFNFMKNNLIHLAFFATPSGMIRYYNLTLQDYDYIDPYWSIFEHIGHLLSIEHAQESYNHFITDLNRKSTDDRYYRRAVRMKDTIMFDVSNNSKIWYKSETQLTGYGLNENLTMLGQAFKAIYLDKAVLGVSGFEFAYDHVVDTMAEHGCPASDDRKWCVLLDEHAYVFFSNQNDISYEDYLVGKGKHISQYFGGLNRIAQRAMALLVENKFYTKLTYTDNQAVCKAEKVVTTSGNRLRPFYPIFRFLMQTFNFMVRLASQISGGFLIWLPNIQFTEAYTASFHEGTDVYPCPKQSSFYFSNKDGKNRPGTTHLVNGNRSERPCKMNAKCSVKMEASFVDGTNLVMVWITQDKASENCYDESECSMEISNQVPFGFEEVKNEETCEENEKRKSKANDVCYSIDDDDSENERRPCSTSPTIVSIFQILFGVFLHFCIF
What is the function of this protein?
May act as an auxiliary subunit of the unc-2 voltage-gated calcium channel which appears to trigger calcium-activated signaling pathways that control the serotonin response.  Inhibiting serotonin sensitivity of the vulval muscles results in egg laying defects.  May act in both neurons and muscle cells to enhance motor activity as it is required for coordinated movement.  Has a role in neural depolarization-induced calcium influx and pharyngeal pumping (PubMed:8462849, PubMed:8807295, PubMed:16838374).  Involved in restricting the expression of the putative olfactory receptor str-2 to only one of the two AWC neurons (PubMed:10571181).
What are the official names of this protein?
Voltage-dependent calcium channel unc-36, Pharyngeal calcium channel subunit alpha-2, Uncoordinated protein 36.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS17_OLEA2
Sequence: MSEAIENRNGRALVGVVVSDKNDKTIVVRVETLVKHPLLKKYIRRRKKFTAHDPNNECKVGDKVKIIEFRPVSRNKRWHLVSILEKAV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RL36_SHEAM
Sequence: MKVRASVKKICRNCKIIKRSGVVRVICVEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TSAD_POLNA
Sequence: MLVLGIESSCDETGVALVDTSASPTPCLLAHALYSQIAMHQPYGGVVPELASRDHIRRVLPLTQDVMKSAQHTLADVDVIAYTRGPGLAGALLVGAGVACSLAAALGKPAMGVHHLEGHLLSPFLSADPPEFPFVALLVSGGHTQLMRVDRVGSYELLGETIDDAAGEAFDKSAKLMGMPYPGGPHLARLALGGDGAAFKLPRPLLHSGNLDFSFAGLKTAVLTQAKKLGTELESRKADLAASTQAAIVEVLVKKTLAALSQTALKRLVVAGGVGANALLRSQLNAACQQRGIRVHYPELEFCTDNGAMIAMAAGMRLQAGLVNLDALRGSYTFDVKPRWNLSEFQSEPALATQNA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_STAHJ
Sequence: MSRKESRMQAFQTLFQLEMKDTELTINEAINFIKDDEPELDFDFIHWLVTGVKDHEPVLDDTIKPHLKDWSLQRLLKTDRIILRMATFELLHSDTPPKVIINEAVELAKQFSDDEHYKFINGVLSNIK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RS9_BRADU
Sequence: MAESIQSLDQLSQLKTAAAPDAPKHEKKVDKFNRAYATGKRKDAVARVWIKPGAGKVTVNSREVEVYFARPVLRMMIEQPFSVAQRSGQYDVICTVAGGGLSGQAGAVRHGISKALTYFEPELRTVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: METXA_CHLAA
Sequence: MEAIVQAPTPEGVGIVRTQRMHWTTPLTLTSGATLGPITLAYETYGELAPDRSNAILILHALSGDAHAAGFHSPTDRKPGWWDAMIGPGRPFDTNRYFVICSNVIGGCRGSTGPSSPHPSDGRPYGSRFPLITIEDMVHAQQRLIDALGIDTLLAVAGGSMGGFQALAWTVEYPQRVRGAILLATSARSSPQTVAWNYIGRRAIMADPRWRGGDYYDSDAPRDGLAVARMLGHITYLCEEKLEQRFGRRVDGDALDLGPRFAIEHYLEHQAARFNDRFDANSYLVITRAMDNWDLTARYGSLTAAFDLTRARFLALAYSSDWLYPPAETYQMAAAAQAAGRSFTTHLITTDAGHDAFLTDVAAQSELIRDFLNRLMTE
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4BH_SINFN
Sequence: MHYRSQRRSVLFTAPGLIVGALAIGAAGGISVSPGDILALVEKPHLLVAVLFVGAFTGIMVEQALSRMRRQDGARGTARAGRNSARRRMPS
What are the official names of this protein?
Uncharacterized protein y4bH.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.