PharMolix/UniProtQA huggingface dataset:
Protein: ELOV5_MACFA
Sequence: MEHFDASLSTYFKALLGPRDTRVKGWFLLDNYIPTFICSVIYLLIVWLGPKYMRNKQPFSCRGILVVYNLGLTLLSLYMFCELVTGVWEGKYNFFCQGTRTAGESDMKIIRVLRWYYFSKLIEFMDTFFFILRKNNHQITVLHVYHHASMLNIWWFVMNWVPCGHSYFGATLNSFIHVLMYSYYGLSSVPSMRPYLWWKKYITQGQLLQFVLTIIQTSCGVIWPCTFPLGWLYFQIGYMISLIALFTNFYIQTYNKKGASRRKDHLKDHQNGSVAAVNGHTNSFSPLENNVKPRKLRKD
What is the function of this protein?
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle.  Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.  May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators (By similarity).  In conditions where the essential linoleic and alpha linoleic fatty acids are lacking it is also involved in the synthesis of Mead acid from oleic acid (By similarity).
What are the official names of this protein?
Elongation of very long chain fatty acids protein 5, 3-keto acyl-CoA synthase ELOVL5, ELOVL fatty acid elongase 5, ELOVL FA elongase 5, Very long chain 3-ketoacyl-CoA synthase 5, Very long chain 3-oxoacyl-CoA synthase 5.
What is the protein family that this protein belongs to?
Belongs to the ELO family. ELOVL5 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree.
Protein: ACCO3_ARATH
Sequence: MEMNIKFPVIDLSKLNGEERDQTMALIDDACQNWGFFELVNHGLPYDLMDNIERMTKEHYKKHMEQKFKEMLRSKGLDTLETEVEDVDWESTFYLHHLPQSNLYDIPDMSNEYRLAMKDFGKRLEILAEELLDLLCENLGLEKGYLKKVFHGTTGPTFATKLSNYPPCPKPEMIKGLRAHTDAGGLILLFQDDKVSGLQLLKDGDWVDVPPLKHSIVINLGDQLEVITNGKYKSVMHRVMTQKEGNRMSIASFYNPGSDAEISPATSLVDKDSKYPSFVFDDYMKLYAGLKFQAKEPRFEAMKNAEAAADLNPVAVVETF
What is the function of this protein?
Enzyme involved in the ethylene biosynthesis.  May promote stem elongation by maximizing the extensibility cells, possibly by activating ethylene biosynthesis, in response to very-long-chain fatty acids (VLCFAs C20:0 to C30:0).
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase 3, ACC oxidase 3, AtACO3.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: DVL1_PANTR
Sequence: MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYELEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGASDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM
What is the function of this protein?
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors.  Plays a role both in canonical and non-canonical Wnt signaling.  Plays a role in the signal transduction pathways mediated by multiple Wnt genes.  Required for LEF1 activation upon WNT1 and WNT3A signaling.  DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (By similarity).
What are the official names of this protein?
Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1.
What is the protein family that this protein belongs to?
Belongs to the DSH family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Cytoplasmic vesicle. Note=Localizes at the cell membrane upon interaction with frizzled family members.
Protein: IP3KB_RAT
Sequence: MAVYCYALNSLVIMNSTNELKSGSPLPSGSETPQPSGRAALSPGSVFSPGRGASFLFPPAESLSLEEPGSAGGWRSGRRRLNSSSGSGGGSSSSNSSSSSGVGSPSWAGRLRGDAQQVVATRILSPPGPEEAQRKLRILQRELQNVQVNQKVGMFEAQIQAQTSAIQAPRSPRLGRARSPSPCPFRSSSQPPERVLAPCSPSEERRTKSWGEQCTETPDANSRRRSRLSTHPSKDKEGVAPLLGPASPTRLGTQSPSTSVRMERGSPASPRCGSPTPMEIDKRTAPSLEHFGTSLTLATKVAASAASAGPHPGHDSVLMEADCELGAMRPWEAHLERRGQFLGRETGSAPEPIRTHIREPPGRVERVHSVGGQGSWTPEVIKRPEEGTVDAQSSELSENPRWSRLPGDPGSVGPEKGGSRIPGIRGPQQTLDSMREGSSALGLLGGSQAAQPGSMDVETGISCGRMLEPLPPGEVTTNLKEPQCLPGDRMGMQPESSIVWPSAVEEAPLIWTCDTGIQLKGTWRSQDGDAHPSCQEKSPDQKDKACSPSNIPAIPAVIITDMGAQEDGGLEEIQGSPRGPLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVQWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMADVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMVEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGSVNRDFKKTKTREQVTEAFREFTKGNQNILIAYRDRLKAIRETLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLIDILTEMSQGSPLT
What is the function of this protein?
Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis.
What are the official names of this protein?
Inositol-trisphosphate 3-kinase B, Inositol 1,4,5-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, InsP 3-kinase B.
What is the protein family that this protein belongs to?
Belongs to the inositol phosphokinase (IPK) family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Endoplasmic reticulum.
Protein: RL20_RICBR
Sequence: MTRAKSGKISKNRHKKILKLAKGYRGRASTCFRVAIEKVEKGLQYAYRDRRNRKRDFRGLWIQRINAAVREHGLVYSQFMGALKKAEIDIDRKVLAELAVNNNEEFASIVEQAKAHI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: FUCM_ECOBW
Sequence: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN746_HUMAN
Sequence: MAEAVAAPISPWTMAATIQAMERKIESQAARLLSLEGRTGMAEKKLADCEKTAVEFGNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGSKGESPKEWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPEVLSQIEQGKEPCNWRRPGPKIPDVPVDPSPGSGPPVPAPDLLMQIKQEGELQLQEQQALGVEAWAAGQPDIGEEPWGLSQLDSGAGDISTDATSGVHSNFSTTIPPTSWQTDLPPHHPSSACSDGTLKLNTAASTEDVKIVIKTEVQEEEVVATPVHPTDLEAHGTLFGPGQATRFFPSPAQEGAWESQGSSFPSQDPVLGLREPARPERDMGELSPAVAQEETPPGDWLFGGVRWGWNFRCKPPVGLNPRTGPEGLPYSSPDNGEAILDPSQAPRPFNEPCKYPGRTKGFGHKPGLKKHPAAPPGGRPFTCATCGKSFQLQVSLSAHQRSCGAPDGSGPGTGGGGSGSGGGGGGSGGGSARDGSALRCGECGRCFTRPAHLIRHRMLHTGERPFPCTECEKRFTERSKLIDHYRTHTGVRPFTCTVCGKSFIRKDHLRKHQRNHAAGAKTPARGQPLPTPPAPPDPFKSPASKGPLASTDLVTDWTCGLSVLGPTDGGDM
What is the function of this protein?
Transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death.
What are the official names of this protein?
Zinc finger protein 746, Parkin-interacting substrate, PARIS.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly localizes to the cytoplasm; probably translocates to the nucleus to repress selected genes.
Protein: YC22_ARATH
Sequence: MQSHQNRSRLSLILRSRFIPSFSSPLSLFVVLAAVPLPIYFSGLLSGRNNKPLSVMRLNSNLASSMVESNISCTTFNILAPIYKRVDQKNHSTRESDFRTLWLARNQRILDLLLHQRSSVICLQEVWVGNEELVNMYHHQLSSSGYTIYQLARTNSRGDGLLTAIHKDHFKVVNYRELLFNDFGDRVAQLLHVKTVIPFPLNGKQDVQQEVIIVNTHLLFPHDSSLSIVRLHQVYKILEYLEAYQKENKLNHMPIILCGDWNGSKRGHVYKFLRSQGFISSYDDAHQYTDSDAHRWVSHRNHRGNICGVDFIWLCNPSDSRKPLRTSWVEAVFSIIKYQLHKASIAEDDAFTFLGAKNHSDSLTYSDFCLALQKVNLTGIPHGLSFEETKELWVRADLDGNGVFDYEELKKIWNMTMVNQPGNCKESVMESKKEEGEDEAIGLKVNKAILFPQEAEKGLWPENYNISDHACLTVQFSPVKMLCS
What are the official names of this protein?
Uncharacterized calcium-binding protein At1g02270.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PSBE_SYNY3
Sequence: MSGTTGERPFSDIVTSIRYWVIHSITIPMLFIAGWLFVSTGLAYDAFGTPRPDEYFTQTRQELPILQERYDINQEIQEFNQ
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RPOZ_VIBCH
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQSGGKDALVPEENDKPTVIALREIEEGLITKDVLDARERQEQQEQEAAELAAVSSIMHNR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: TCAF3_RAT
Sequence: MATTPDAAFEALMNGVTSWNLPKEPTPSELLLTGEAAFPVMVNDKDQVLIAASFYGHGRLVVLSHESYLLHAGLAPFLLNAVSWLCPSPEAPIAVHSSLASLVKILGDSGVNAVVQPEPREALGVYCIDAYSETLTETLIRFMKNGGGLLIGGQALTWAVHHGHEKVLSSFPGNQVTSVAGVYFTDISGNRDWFKVSKEIPNLTLYVQCEDELKYDQQQLLKGMSEMDIETGPVPSQLLVHGQRAFPLGVDNSFNCFLAAARFGRGRVVLAGHESLILNQTMLPFVLNALRWLMGNQTGRIGLASEMKALKSVLPNSSFEWSETELLTNDLSVFCSCSLGKTDPKKVEEFVAEGGGLLIGAEAWMWGRRNPDSNCMTQYPNNIILKRFGVGIISQVVQRGRFPVPNPEVINYHIRRALSQYESVIHSQGSSLQEGWLNKLSQDCFYMFQMTHQRISIYDSVKEHALKMIQSQGFPSVTEQHPITKGSSQAFLLSLAYELFKSGVDRSQLLPPPTLLSPTESPMTIKISTGNDNSWVSTGLYLPEGQVAQVTLPTEATHAKLKVLIGCHIDNISQAKTYIRPPVMTYVYHLTSSQTSISWLYGGLLYIMVPDKYNQDNVSVTISGAVSAPYFRLGKTTQEEWKNLIEHSKAPWGELATDNIILTIPTVNLKVLQDPYPLLQLWDKIVKAVAKLAARPFPFQRPERIVLDKQISFGFLHSGYPIMGLIIIVEGIINEFKIRSHGVWGVTHELGHNHQKPGWTFRPHTTEALCNLWSIYVHETVLNIPRDQAHPSLNPELRKQRIKDHLNKGAPLSNWIVWTALETYLQLQEGFGWEPFIQLFANYQTLTGLPQNNEDKMNLWVKKFSEVVQKNLAPFFKAWGWPVQHAVAKSLASLPEWQENPMKMYTAESTEHTE
What is the function of this protein?
May play a role in the regulation of the cation channel TRPM8 activity.
What are the official names of this protein?
TRPM8 channel-associated factor 3, Experimental autoimmune prostatitis antigen 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the TCAF family.
Protein: DAPF_BRUA2
Sequence: MATKAAFARMNGLGNQIIVADMRGRADSITSAAAIRLASDSETAFDQIMAIHDPRTPGTDYYIAIINCDGTQAQACGNGTRCVVQALAAETGRHAFTFETRAGILTATEHDDGLISVDMGTPRFDWQDIPLAQAVADTRKIELQVGPADAPVLHSPSIASMGNPHAVFWVDKDVWSYELDKFGPLLENHPIFPERANISIAHVTSSDTIDLRTWERGAGLTRACGSAACAAAVSAARTGRTGRKVTVNVPGGPLLIEWRDDDHVMMTGPAEWEFSGTFDPATGEWSRDTQGLQGSGNADRGAA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_CAMC1
Sequence: MTFSQIILTLQNYWQEQGCVILQPYDMPAGAGTYHQATFLRSLGPKPWATAYVAPSRRPTDGRYGENPNRLGAYYQFQVLIKPSPENIQELYLKSLERLGLNLKNHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIACELISGEITYGLERLAMYLQDVNSVYDIVWDDSNGSIVTYADVHKQGEYEWSKYNFEVANVDMLFNQFENAFNECKRCLEAKISLPAYDYCMLAAHTFNVLDARGAISVTQRQDYILKIRELAKECALTYKESLEQK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURK_MYCBO
Sequence: MMAVASSRTPAVTSFIAPLVAMVGGGQLARMTHQAAIALGQNLRVLVTSADDPAAQVTPNVVIGSHTDLAALRRVAAGADVLTFDHEHVPNELLEKLVADGVNVAPSPQALVHAQDKLVMRQRLAAAGVAVPRYAGIKDPDEIDVFAARVDAPIVVKAVRGGYDGRGVRMARDVADARDFARECLADGVAVLVEERVDLRRELSALVARSPFGQGAAWPVVQTVQRDGTCVLVIAPAPALPDDLATAAQRLALQLADELGVVGVLAVELFETTDGALLVNELAMRPHNSGHWTIDGARTSQFEQHLRAVLDYPLGDSDAVVPVTVMANVLGAAQPPAMSVDERLHHLFARMPDARVHLYGKAERPGRKVGHINFLGSDVAQLCERAELAAHWLSHGRWTDGWDPHRASDDAVGVPPACGGRSDEEERRL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide synthase, N5-CAIR synthase, 5-(carboxyamino)imidazole ribonucleotide synthetase.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: SLYA_SODGM
Sequence: MESPLGSDLARLVRVWRALIDHRLKPLELTQTHWITLHNICQLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRHTCANDRRAKRIKLTESAEPIIKEVNNVIDSTRNEILNGISQEEIQLLSNMIAKLEKNILELYNKS
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: PAND_PELPD
Sequence: MERIMLKSKIHRATITGADLEYEGSITIDRDLMDAADIVSYEKVAVWDVTNGSRLETYAIEGERGSGVICLNGAAARLVAPKDVVIIASFVNMSNQAAIKHEPKLVFVDGKNRMLPTRAEEAGQARVRCVH
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAID_ECOLC
Sequence: MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMPVEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR
What is the function of this protein?
Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
What are the official names of this protein?
Carnitinyl-CoA dehydratase, Crotonobetainyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: RL24E_THESM
Sequence: MARWNVCSYCGKEFEPGTGKMYVRNDGRVYFFCSRKCEKYFFMGRNPRKLKWTKAFEEAKLQRAKRK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: CO1A2_SCESW
Sequence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
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-2(I) chain, Alpha-2 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: SYE_STRPD
Sequence: MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIEDTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKAYKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAVNESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGDDHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYMPEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKHADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEAEKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRIAVSGEMHGPELPNTIYLLGRDKSIEHIKNML
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSA3_YARLI
Sequence: MSAKSDSRNNKAVKSDEPKKRRRKKARTAEVSDSDSSDSESDRAEEDDNEDNEDTTNHVIDEGDVEMMEFDKDDAAAAASAQTMDIPAELQSLPADSANPEFQKFYLNLVTSEFGKDMDELRTSKTFNDNTLGLLVDALKQGVNVFDEKVQGEIVQQQS
What is the function of this protein?
Required for efficient biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome assembly protein 3.
What is the protein family that this protein belongs to?
Belongs to the RSA3 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TSAD_PROMA
Sequence: MQTVLSLETSCDESAAALVKFNEGKFEILANSIASQANEHAKWGGVVPEIASRRHLESLPFLIQEVFSQSGINFSDVNAIAATVAPGLSGALLVGSVTARTLSCLHDLPFLGIHHLEGHLCSALLSENPPVPPYLVLLVSGGHTELIQVDRNFTYKRVGRSHDDAAGEAFDKVARLLGLSYPGGPAIEKFAKKGDPASFHFPKGRVSKPEGGFYPYDFSFSGLKTAVLRKVESIRSEGKQIPLANLAASFENVVSEVLVERSVKYAFDHGLHSLVMVGGVAANTCLRKMMVSKAEDKAIDVYMAPKAFCTDNAAMIGTAALVRLISGTSPSSLELGVSARFELDQSDLLYKSEPPF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIG12_PANTR
Sequence: MLLLLLLLLLPPLLCGRVGAKEQKDYLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTDSDPVHGYWFRAGDHVSRNVPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFRVERGNMKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHCNWTASSPVYGSWFKEGADIPCDIPVATNTPSGKVQEDTQGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHLPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVSSLEPTISRSSMLSLIPKPQDHGTSLTCQVTLPGAGVTTTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAVGGAGATALVFLSFCIIFVVVRSCRKKSARPAVGVGDTGMEDTNAVRGSASQGPLIESPADDSPPHHAPPALATPFPEEGEIQYASLSFHKARPQYPQEQEAIGYEYSEINILK
What is the function of this protein?
Putative adhesion molecule that mediates sialic-acid dependent binding to cells.  The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
What are the official names of this protein?
Sialic acid-binding Ig-like lectin 12, Siglec-12, Sialic acid-binding Ig-like lectin-like 1, Siglec-L1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RECO_MOUSE
Sequence: MGNSKSGALSKEILEELQLNTKFTEEELSAWYQSFLKECPSGRITRQEFESIYSKFFPDSDPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMIKPEDVKLLPDDENTPEKRAEKIWAFFGKKEDDKLTEEEFIEGTLANKEILRLIQFEPQKVKERIKEKKQ
What is the function of this protein?
Acts as a calcium sensor and regulates phototransduction of cone and rod photoreceptor cells (By similarity).  Modulates light sensitivity of cone photoreceptor in dark and dim conditions (PubMed:25673692).  In response to high Ca(2+) levels induced by low light levels, prolongs RHO/rhodopsin activation in rod photoreceptor cells by binding to and inhibiting GRK1-mediated phosphorylation of RHO/rhodopsin (By similarity).  Plays a role in scotopic vision/enhances vision in dim light by enhancing signal transfer between rod photoreceptors and rod bipolar cells (PubMed:15882641).  Improves rod photoreceptor sensitivity in dim light and mediates response of rod photoreceptors to facilitate detection of change and motion in bright light (PubMed:29435986).
What are the official names of this protein?
Recoverin, 23 kDa photoreceptor cell-specific protein, Cancer-associated retinopathy protein, Protein CAR.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Photoreceptor outer segment membrane; Lipid-anchor; Cytoplasmic side. Perikaryon. Note=Primarily expressed in the inner segments of light-adapted rod photoreceptors, approximately 10% of which translocates from photoreceptor outer segments upon light stimulation (PubMed:15961391). Targeting of myristoylated protein to rod photoreceptor outer segments is calcium dependent (By similarity).
Protein: PETG_SYNR3
Sequence: MIEPLLCGIVLGLIPVTLLGLFVAAWNQYRRGSALGG
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.