PharMolix/UniProtQA huggingface dataset:
Protein: SCPA_STAA8
Sequence: MYEVKLDAFNGPLDLLLHLIQKFEIDIYDIPMQALTEQYMQYVHAMKQLEINIASEYLVLASELLMIKSKMLLPQSTSDMDVDDDPREDLVGRLIEYQNYKEYTAILNDMKEERDFYFTKRPTDLSHLETDESWDPNHTIDLTELIVAYQRVKNRVELNTPKSVEIRKETFTIQQATEQVTSRLKDKDHFNFFSLFTFSEPIEQVVTHFLAILEMSKAGIINIEQQRNFEDINIIRGVNYHFG
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: DTD_VIBPA
Sequence: MIALIQRVSEAAVRVDGEVVGEIDTGLLVLLGVEKDDDEAKAKRLMERVTTYRVFEDDEGKMNLNVKQVNGKVLVVSQFTLPADTKKGTRAGFSRGAHPADAERLYDYFSDLCEQELPTERGRFAADMKVSLINDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_SALTY
Sequence: MHFTATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGLGILASKFVLEWNHWIAFVLLIFLGGRMIIEGIRGGSDEDETPLRRHSFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMIGRFIGPMLGKRAEILGGVVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADRM1_HUMAN
Sequence: MTTSGALFPSLVPGSRGASNKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNPPMPGALGASGSSGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGNGASTAASPTQPIQLSDLQSILATMNVPAGPAGGQQVDLASVLTPEIMAPILANADVQERLLPYLPSGESLPQTADEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNNAKPEQKEGDTKDKKDEEEDMSLD
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins (PubMed:16815440, PubMed:16906146, PubMed:16990800, PubMed:17139257, PubMed:18497817, PubMed:24752541, PubMed:25702870, PubMed:25702872).  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required (PubMed:16815440, PubMed:16906146, PubMed:16990800, PubMed:17139257, PubMed:18497817, PubMed:24752541, PubMed:25702870, PubMed:25702872).  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair (PubMed:16815440, PubMed:16906146, PubMed:16990800, PubMed:17139257, PubMed:18497817, PubMed:24752541, PubMed:25702870, PubMed:25702872).  Within the complex, functions as a proteasomal ubiquitin receptor (PubMed:18497817).  Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation (PubMed:16906146, PubMed:16990800, PubMed:17139257, PubMed:24752541).  UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex (PubMed:16906146, PubMed:16990800, PubMed:17139257, PubMed:24752541).
What are the official names of this protein?
Proteasomal ubiquitin receptor ADRM1, 110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Proteasome regulatory particle non-ATPase 13, hRpn13, Rpn13 homolog.
What is the protein family that this protein belongs to?
Belongs to the ADRM1 family.
Protein: MATK_KIGAF
Sequence: MEEIQRYLQLERSQQHDFLYPLIFQEYIYAFAHDRGFSRSILSENPGYDNKSSLLIVKRLITRMYQQNHFLISPNDSNQNRFLARNKNLYFQIISEGFAFIVEIPFSLRLISCLEGKKRVKSQNLRSIHSIFPFLEDNFSHFNFVLDIGIPHPIHVEILVQILRYWVKDASSLHLLRFFLNEYCNWNSLITPKKGSSSFSKRNQRLFLFLYNSHVCEYESIFVFLRNQSSHLRSTSSGVLLERIYFYEKIERLVNVFVKVKDFQANLWFVKEPCMHYIRYQRKSILASKGTSLFMNKWKCYLVTFWQWHFXLWFHPRRIYINQLSNHSLEFLGYLSNVRMNPSVVRSQVLENSFLINNAIKKFDTLVPIIPLIASLAKAKFCNVLGHPISKPVRADLSDSNIIDRFGRICRNLSHYHSGSSKKKSLYRIKYILRLSCARTLARKHKSTVRAFLKRLGSELLEEFLMSEEDVLFLTFPKASSALWGVYRSRIWYLDIICINDLANHKSKF
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFP_GLAP5
Sequence: MASYSTNDFKPGLKFIQDGEPCVIVENEFVKPGKGQAFTRTKIRKLISGKVLEINFKSGSTVEAADVVDYNYTYSYKDEDFWYFMHPETFEQISVDSKALGDNDKWLVDQAECIITLWNGSAIGVTPPNFVELEVIETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQIGEVIRVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXG2_MOUSE
Sequence: MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGESIYSDEQSKFTCNTRQPGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGTRRLPRAQLPPPPPGWPDTTDLGEAEPILALEEDEDEEPGAPEGPGEDTEEERAEDVAAKGGGGDGKTVVTPGPAGQHDGRRRIQREGLMRVYVAQLVVRAAFEVAFLVGQYLLYGFEVPPFFACSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRGRRGASAAGPGPTPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALRDGAAVAAVSADRDSPPCAGLNATSRGAPRVGGLASGTGSATSGGTVGEQSRPGAQEQLATKPRAGSEKGSTGSRDGKATVWI
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.  May play a role in myelination in central and peripheral nervous systems.
What are the official names of this protein?
Gap junction gamma-2 protein, Connexin-47, Cx47, Gap junction alpha-12 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Gamma-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: RL7_WIGBR
Sequence: MSINKQQILDAVSEMSVLEISELVSMMEKKFGVSSINNNNINVNKVDESVEEKSEFDVLLLEIGKNKISVIKSVRSALSLGLKESKDLIESELPITLKTGLNKKDAESLKKEIETSGARIELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: AZOR_CHRVO
Sequence: MKLLHLDSSILADNSVTRELSAVVADTLRQRHANVETSYRDLAANPIAHLSGEIVGARFAPESDWTATQRSEAALSEQLIEEFIAADVLVIGAPMYNFSIPTQLKSWIDRVAAAGRTFKYTENGPVGLVPNKKVVLVSARGGVHSGEQGSLMDFQEDYVVKVLGFLGVSDVEIIRAEAIGMGPDKRATSIHLAKEAIAKLAL
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: QUEC_YERPP
Sequence: MKRAVVVFSGGQDSTTCLIQALQQYDEVHCITFDYGQRHRTEIDVARELALQLGATAHKVLDVGMLNELAVSSLTRDSIPVPSYDANADGALPSTFVPGRNILFLTLASIYAYQVQAQAVITGVCETDFSGYPDCRDEFIKALNHAIDLGIGRDIAFITPLMWLDKAETWALADYYQQLDLIRHHTLTCYNGIKGDGCGQCAACHLRAKGLASYMANKQQVILNLKQKVGLA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MIAB_GLOC7
Sequence: MTTSERRYHITTFGCQMNKADSERMAGILEDIGYQWSDDPNEADLVLYNTCTIRDNAEQKVYSYLGRQAKRKHEKPDLTLIVAGCVAQQEGEKLLRRVPELDLVMGPQHANRLQDLLQEVLAGNQVVATEPIHIVEDITKPRRESTVTAWVNVIYGCNERCTYCVVPNVRGVEQSRTPQAIRAEMVELGQQGYKEITLLGQNIDAYGRDLPGVTESGRHQHTLTDLLYYVNDVPGIERIRFATSHPRYFTERLIVACKELPKVCEHFHIPFQSGDNDLLKAMKRGYTHERYRQIIDKIREYMPDASISADAIVGFPGETEAQFENTLKLVEDIGFDQLNTAAYSPRPGTPAALWDNQLSEEVKSDRLQRLNHLVAIKAAERSQRYLGRIEEVLVEDVNPKDLTQVMGRTRGNRLTFFTGDINQLKGQLVEVKITDVRAFSLTGEPVKILSTSLS
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAP1_ORYLA
Sequence: MDPSQHNPPVGHQIVHVRGDSETDLEALFNAVMNPKGAVVPQSVPMRMRKLPDSFFKPPEPKSHSRQASTDAGSGGVLTPHHVRAHSSPASLQLGAVSGGSLSGMASAGASPQHLRQSSYEIPDDVPLPPGWEMAKTSSGQRYFLNHIDQTTTWQDPRKALLQLNQATPPSTVPVQQQNLLSPASGPLPEGWEQAITPEGEIYYINHKNKTTSWLDPRLETRYALNQQRITQSAPVKQGGPLPPNPHGGVMGGNNQMRLQQMEKERIRLKQQELLRQSQRPQIDLQPSTANQDAEHCDELALRNQLPTSMDQDGSSNPVSSPMAQDARTMTANSNDPFLNSVSSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDPLAPSMATQPSRFPDYLDTIPGTDVDLGTLEGESMAVEGEELMPSLQEALSSDILNDMESVLAATKIDKESFLTWL
What is the function of this protein?
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity).  Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation (PubMed:25778702).
What are the official names of this protein?
Transcriptional coactivator YAP1, Yes-associated protein 1, Protein hirame, Protein yorkie homolog, Yes-associated protein YAP65 homolog.
What is the protein family that this protein belongs to?
Belongs to the YAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Both phosphorylation and cell density can regulate its subcellular localization. Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus. At low density, predominantly nuclear and is translocated to the cytoplasm at high density.
Protein: MEI3A_XENLA
Sequence: MAQRYDEMLHYPTLDGMPLAGFGDAHTGRALQHHSLSQSAPYGSTGAGHRVPMPPGMGSNDGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDNSGSFPGGDVCSSDSFNEDIAVFAKQVRTEKPLFSSNPELDSLMIQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIDDRDGSSKSDLEDFTGSCTSLSDQNNSWLRDHDETGSAHSGTPGPSSGGLASQSGDNSSEQGDCMDNSVASPSTGDDDDLDRDKKRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTGQGGAPYSPDGQNMGGYVMDGQQHMGIRPPGFQGIPGDYTAAPSTMPMGFPPAGYTPAIPPHSAGLRHGPSLHSYLPGHPHHASMILPAGASPHHLVSAQSPADALLNGQNIDIHAH
What is the function of this protein?
Caudalizing protein which is required to pattern the anterior/posterior (A/P) axis during central nervous system (CNS) formation.  Inhibits anterior neural expression and acts as a transcriptional activator to induce posterior neural gene expression.  Maintains a proper A/P balance required for hindbrain formation by activating the FGF/MAPK pathway, which modulates the planar cell polarity (PCP) pathway.  Interacts with retinoid signaling during hindbrain patterning.
What are the official names of this protein?
Homeobox protein meis3-A, XMeis3.
What is the protein family that this protein belongs to?
Belongs to the TALE/MEIS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYC5_CHACT
Sequence: GVIPCGESCVFIPCISSVVGCSCKNKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Chassatide C5, Cyclotide chaC5.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: MENE_LISMO
Sequence: MTNWLQKRVRLSPKETALVFEGKEETFEEISEAVERLAGKLFALGIRKDEMIALLGKNDRMTFLLIHALQQLGAVTLFLNNRLTKKEIAYQLANAEVKQVIVADTFEDKVGAGISYSELAETDYKEPELLETWDLSRTASIMYTSGTTGKPKGVIQTYENHWWSAVASVLNLGLTEKDSWLCAVPIFHISGLSIMMRSVIYGIPVYLEEHFDEEKITQLLESGKVSTISVVTSMLERLLKIHGGSYHPNVRTILLGGGPASKTVLEICKQRDIPLVQSFGMTETASQIVTLPPKDALNKIGSSGKALFPAEVKIADDGEILLKGPSITPGYLHNKKATEASFVDGWFKTGDIGYLDEEGFLFVVERRSDLIISGGENIYPTEIEHVIGEYVAVKEVAVIGQPDDKWGSVPVAFIVAEETFDEDELQLICQTNLASYKIPKQIIIVEKLPKTASGKIQRNKLKERHSK
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: TATB_MYCA1
Sequence: MLGSLSWEHMLVLVVVGLVVLGPERLPGAIRWTSNALRQARDYLSGVTTQLREDLGPEFDDLRVPLSELQKLRGMTPRAALTKHLLDGDDSFLTGAFDRPVNGAAAQPPPAPAPPPEPHRPGQTPFDADAT
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL36_METI4
Sequence: MKVRASVRRRTADCQVVRRKGRIYIINKKNPRLKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HEMH_PROM3
Sequence: MARVGVLLMNLGGPERIQDVGPFLFNIFADPEIIRLPNPALQRPLAWLISTLRSSKSEQAYRSIGGGSPLRRITEQQARELQSLLRQRGIDATSYVAMRYWHPFTESAVADIKADGIDQVVVLPLYPHFSISTSGSSFRELQRLRQTDESFRKLPIRCIRSWYDHPGYVLAMAELIAEQVRLSDVPEEAQVFFSAHGVPKSYVEQAGDPYQKEIEACTTLIMAELENLLGYGNPHSLAYQSRVGPEEWIQPYTDEVIEQLGEAGTRDLVVVPISFVSEHIETLAELDIEYRELATEAGIVHFRRVPALDTYPTFIEGLADLVGSSLEGPEINLDEAAKLAGRVKFYPQERWQWGLNTSSEAWNGRIAMLGFAAFLLELISGHGPLHAIGLL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHAN2_RAT
Sequence: MKSLLNAFTKKEVPFREAPAYSNRRRRPPNTLAAPRVLLRSNSDNNLNAGAPEWAVCSAATSHRSLSPQLLQQTPSKPDGATKSLGSYAPGPRSRSPSLNRLGGAGEDGKRPQPPHWHVGSPFTPGANKDSLSTFEYPGPRRKLYSAVPGRLFVAIKPYQPQVDGEIPLHRGDRVKVLSIGEGGFWEGSARGHIGWFPAECVEEVQCKPRDSQAETRADRSKKLFRHYTVGSYDSFDAASDCIIEDKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVTRNLDPDDTARKKAPPPPKRAPTTALTLRSKSMTAELEELGLSLVDKASVRKKKDKPEEIVPASKPSRTAENVAIESRVATIKQRPTSRCFPAASDVNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPPPSPTTYNCPRSPTPRVYGTIKPAFNQNPVAKVPPATRSDTVATMMREKGMFYRRELDRFSLDSEDVYSRSPAPQAAFRTKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSMEIDPQATEPGQLRPDDSLTVSSPFAAAIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRMQPSKFPEEGGFGDEDETEQPLLPTPGAAPRELENHFLGGGEAGAQGEAGGPLSSTSKAKGPESGPAAALKSSSPASPENYVHPLTGRLLDPSSPLALALSARDRAMQESQQGHKGEAPKADLNKPLYIDTKMRPSVESGFPPVTRQNTRGPLRRQETENKYETDLSKDRRADDKKNMLINIVDTAQQKSAGLLMVHTVDIPVAGPPLEEEEDREDGDTKPDHSPSTVPEGVPKTEGALQISAAPEPAAAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFLFTEPLPPPLEFANSFDIPDDRAASVPALADLVKQKKSDTPQPPSLNSSQPANSTDSKKPAGISNCLPSSFLPPPESFDAVTDSGIEEVDSRSSSDHHLETTSTISTVSSISTLSSEGGESMDTCTVYADGQAFVVDKPPVPPKPKMKPIVHKSNALYQDTLPEEDTDGFVIPPPAPPPPPGSAQAGVAKVIQPRTSKLWGDVTEVKSPILSGPKANVISELNSILQQMNRGKSVKPGEGLELPVGAKSANLAPRSPEVMSTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRTSGPRRAPSPVVSPTELSKEILPTPPSAAAASPSPTLSDVFSLPSQSPAGDLFGLNPAGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNLGEHKETFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR
What is the function of this protein?
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton.  May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
What are the official names of this protein?
SH3 and multiple ankyrin repeat domains protein 2, Shank2, Cortactin-binding protein 1, CortBP1, GKAP/SAPAP-interacting protein, Proline-rich synapse-associated protein 1, ProSAP1, SPANK-3.
What is the protein family that this protein belongs to?
Belongs to the SHANK family.
What are the subcellular locations of this protein?
Apical cell membrane. Cytoplasm. Synapse. Postsynaptic density. Cell projection, growth cone. Cell projection, dendritic spine. Note=Colocalizes with cortactin in growth cones in differentiating hippocampal neurons. Present in the dendritic spines of cerebellar Purkinje cells (By similarity). Colocalizes with cortactin in growth cones in differentiating hippocampal neurons. Colocalized with PDE4D to the apical membrane of colonic crypt cells.
Protein: FADA_AERHH
Sequence: MKDVVIVDCIRTPMGRSKGGAFRNVRAEDLSAHLMKSILLRNPNLDPNEIEDIYWGCVQQTLEQGFNIARNAALLAGIPKQVGAVTVNRLCGSSMQALHDASRAIQVGDGDIFIIGGVEHMGHVPMSHGVDFHPGMAKSVAKASGMMGLTAEMLGKLHGISRQQQDEFAARSHRRAHAATVEGRFAKEIVGLEGHDASGARFFYDYDEVIRPETTVETLSQLRPVFDPVNGTVTAGTSSALSDGAAAMLVMSADRAKALGLTPRAKIRAMAVAGCDAAIMGYGPVPATQKALKRAGLTIGDIDLFELNEAFAAQSLPCVKDLGLQDVVDEKVNLNGGAIALGHPLGCSGARISTTLLNLMEEKDATLGVATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_BURCM
Sequence: MRTLDKRIAPNVKLAASLVARAPTLTLAYDARCKSRLAATLDTGEDVAVVLPRGTVLRDGDVLVADDGALVRIAAAPETVLLVRAGDPLTLMRAAYHLGNRHTPVEIGDGYLKLEADPVLADMLRRLGTQVEPTSAPFQPEAGAYGGGHKHGHDATFAEDYALAQQVFGEHHGHSHSHDHDHDHDHQHGPGCTHGHRGHDHH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLD_FRATT
Sequence: MNDVVLSCKNVSKKYTEFKTDIAILKDVNLEIKKGEKVAILGLSGSGKTTLLNVLGGLDKCSAGEVYLMGERFDNQSVNKRAKMRNKHLGFIYQLHHLLPEFTAIENVMIPLAITKKYTKKESIKLANEILKKVGLDHRADHKPAELSGGERQRVAIARALVTNPNCILADEPTGNLDSQRSESIFALMQQLSDDFGTSFVIVTHDEKLASRMNKIYRLVDGELELVINSN
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACDH_SHEWM
Sequence: MVNKKINIALIGSGNIGTDLMIKALRSSTLNPVWMVGIDENSDGLKRAKALGLKTTHLGIDELLTHIEADNIQIAFDATSAYVHEENNRKLQSKGVKVIDLTPAAIGPYCIPPVNLESLLSQTENQTQINDGSISGNLNMVTCGGQATIPIIAAISRVQSVDYGEIVATIASKSAGPGTRKNIDEFTRTTADAIEQIGGARQGKAIIVMNPAEPPLMMRDTVHCLTQDEPDVEAITASVLSMIEQVQEYVPGYRLKNGPVFDGNRVSVFLEVAGLGDYLPEYAGNLDIMTSAALCTGEMLARNLRSNMSVKDSHH
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: Y258_HELPY
Sequence: MFIVAVLMLAFLIFVHELGHFTIARICGVKVEVFSIGFGKKLCFFKLFGTQFALSLIPLGGYVKLKGMDKEENGMNETTDDSYAQKSPFQKLWILFGGAFFNFLFAILVYFFLALGGEKVLLPVIGDLDKNALEAGLLKGDKILSINHKKIASFREIRSVVARARGELVLEIERNHQVLEKRLTPKIVAVISDSNDPNEMIRYKAIGIKPDMQKMGVVSYSLFQAFEKALSRFKEGVVLIVDSLRRLIMGSSSVKELSGVVGIVGALSHANSLSMLLLFGAFLSINLGILNLLPIPALDGAQMLGVVFKNIFHITLPTPIQNALWLAGVGFLVFIMFLGLFNDLTRLL
What are the official names of this protein?
Putative zinc metalloprotease HP_0258.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCL5_CAVPO
Sequence: MKVSAAALCVILTTAALCVPASASPYASDTTPCCFAYISRALPRTHIKEYFYTSSKCSNLAVVFVTRKNRQVCANPEKKWVREYINSLEMS
What is the function of this protein?
Chemoattractant for blood monocytes, memory T-helper cells and eosinophils.  Causes the release of histamine from basophils and activates eosinophils.  May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5.  May also be an agonist of the G protein-coupled receptor GPR75.  Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases.  By activating GPR75 may also play a role in insulin secretion by islet cells.
What are the official names of this protein?
C-C motif chemokine 5, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ANR46_DANRE
Sequence: MSYVFINDSSQTSVPLLQACIDGDLSFARRLLETGCDPNIRDHRGRTGLHLAAARGNVDICRFLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHNGSTPLVLAKRRGVNKDAIRLLEGLEEQEVKGFNRGAHSKLEAMQMAESESAMESHSLLNPNLQNSEGVLSSFRSTWQEFVEDLGFWRVLLLLVVIALLSLGIAYYVSGVLPFSASQLELVH
What are the official names of this protein?
Ankyrin repeat domain-containing protein 46.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.