PharMolix/UniProtQA huggingface dataset:
Protein: RCF1_CLAL4
Sequence: MNTLQKIAYRSKQQPLVPLGTLLTTAAVVLAAKSLKQGRKKDTQRYFRYRVGFQAFTLVALVIGGMYYQKESAEQKQTREDKLREKAKLREQLWIEELERRDQLIKARKQRLEESKKELMKVAQEGFEQERERELKKEDK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TREA_SALA4
Sequence: MIPPEIRRSVLLQKAIKLALAGTLLTFASFSATAADPSSDTETPQPPDILLGPLFNDVQNAKLFPDQKTFADAIPNSDPLMILADYRMQRNQSGFDLRHFVDVNFTLPKAGEKYVPPAGQSLREHIDGLWPVLTRSTKNVEKWDSLLPLPESYVVPGGRFREIYYWDSYFTMLGLAESGHWDKVADMVANFGYEIDAWGHIPNGNRTYYLSRSQPPFFAFMVELLAQHEGDDALKEYLPQLQKEYAYWMEGVETLQPGQQNQRVVKLEDGSVLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLSTIRTTTIVPVDLNALLYQLEKTLARASAAAGDRAKASQYDALANARQKAIEMHLWNNKEGWYADYDLQNNKIRNQLTAAALFPLYVNAAAKDRAAKVAAAAQAHLLQPGGLATTSVKSGQQWDAPNGWAPLQWVAAEGLQNYGQDDVAMEVTWRFLTNVQHTYDREKKLVEKYDVSSTGTGGGGGEYPLQDGFGWTNGVTLKMLDLICPQEKPCDSVPSTRPASLSATPTKTPSAATQ
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL28_ACAM1
Sequence: MGKKCQLTGKKANNAFAVSHSHRRTHKLQEANLQWKRVWWPQEKRWVKLRLSTKAIKTLEKKGLAAFAREAGINLNQV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TUSC_ECO7I
Sequence: MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGVFQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPKB_ASPFC
Sequence: MVQQPPQGGSRKISFNVSEQYEIQDVIGEGAYGVVCSAIHKPSGQKVAIKKITPFDHSMFCLRTLREMKLLRYFNHENIISILDIQRPRNYESFNEVYLIQELMETDMHRVIRTQDLSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANCDLKVCDFGLARSAASTDDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGKPLFPGKDYHHQLTLILDVLGTPTMEDYYGIKSRRAREYIRSLPFKKKIPFKALFPKSNELALDLLEKLLAFNPAKRITVEEALRHPYLEPYHDPDDEPTAPPIPEGFFDFDKNKDALSKEQLKTLIYEEIMR
What is the function of this protein?
Mitogen-activated protein kinase (MAPK) that plays a role in conidiation and regulation of secondary metabolite biosynthesis (PubMed:30914505).  Acts as a repressor of dihydroxynaphthalene (DHN)-melanin production (PubMed:30914505).
What are the official names of this protein?
Mitogen-activated protein kinase mpkB, MAPK mpkB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Translocates into the nucleus upon exposure to caspofungin stress, and this is dependent on the cross-talk interaction with mpkA.
Protein: RS13_CHLAB
Sequence: MPRIIGIDIPAKKKLKISLTYIYGIGPALSEEIIAKLQLNPEARAAELTEEEIGRLNSLLQSDYVVEGDLRRRVQSDIKRLISIHAYRGQRHRLSLPVRGQRTKTNSRTRKGKRKTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: VATE_BORAP
Sequence: MQFEVKDLINKIKKDGLEEAERVSNDIILKAKREAEEIVARAEESARALKAKSEKEINDYKSHALEASRQAIRDLIIGVEKNLKSLFENTLKDNVVEVFSDNNFLAELIIKITDSWAKEEKLVVQLNESDFSSLEQILRLKLGNKLAQGIEIKPFKGISKGFKIQKKNIGLQYDFSAETVADILFDYLNPRFKEIIKVV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: CM3C_CONBU
Sequence: MMSKLGVLLTICLLLFPLFALPQDGDQPADRPAERMQDDLSSEQHPLFEKRIVDRCCNKGNGKRGCSRWCRDHSRCCGRR
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels.  Extremely potent inhibitor of Nav1. 4/SCN4A (96% inhibition at 1 uM).  The inhibition is very slowly reversible.
What are the official names of this protein?
Mu-conotoxin BuIIIC.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMM_SORC5
Sequence: MERRYVPVADVARPHGVQGELRLRLYNEASDLLLTRPPIRLRLPDGSARDAKIVATRPVDKALLVRIAGIDDRDAAEALRGATVCVPRDAFAPLSEGEFYACDVEGARVMTPDGDLLGHVRSLQSYPTCDVLVVERQGADSIEVPLTESFVSSVDAERQVVQLATLEGLV
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKFC_MOUSE
Sequence: MSSKKMVNSVEGCADDALAGLVASNPDLQLLQGHRVALRSDLDTLKGRVALLSGGGSGHEPAHAGFIGKGMLTGVIAGSVFASPPVGSILAAIRAVAQAGTVGTLLIVKNYTGDRLNFGLAMEQAKAEGISVEMVIVEDDSAFTVLKKAGRRGLCGTVLIHKVAGALAEEGMGLEEITKRVSVIAKTMGTLGVSLSSCSVPGATHTFELAADEIELGLGIHGEAGVRRIKIAPVDQIVTLMLDHMTNTSNIFHVPVRSGSSVVLIVNNLGGLSFLELGIIADAAIRLLEGRGVKVARALVGTFMSALEMPGVSLTLMLVDEPVLKLIDAETTAKAWPHMAKVSVTGRKRIRAAPTEPPEAPEATAAGGVTSKQMALVLDRICTTLIGLEEHLNALDRAAGDGDCGSTHSRAAKAIQGWLKEGPSLTSPAQVLSRLSVLLLERMGGSSGALYGLFLTAAAQPLKAKTDLPTWSAAMDAGLESMQKYGKAAPGDRTMLDSLWAAAQEFQAWKSPGASLLPVLTKAVKSAEAAAEATKNMEAGAGRASYISSAQLDQPDPGAVAAAAIFRAILEVLQTQGA
What is the function of this protein?
Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate.  Represses IFIH1-mediated cellular antiviral response.
What are the official names of this protein?
Triokinase/FMN cyclase, Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing).
What is the protein family that this protein belongs to?
Belongs to the dihydroxyacetone kinase (DAK) family.
Protein: RS15_SHIB3
Sequence: MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RL28B_MYCTU
Sequence: MSAHCQVTGRKPGFGNTVSHSHRRSRRRWSPNIQQRTYYLPSEGRRIRLRVSTKGIKVIDRDGIEAVVARLRRQGQRI
What are the official names of this protein?
50S ribosomal protein L28-2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GLMM_MARMM
Sequence: MGKKYFGTDGVRGQTNSFPMTAENALRLGMAAGRYFVRHTGRHSVVIGKDTRLSGYMIESALVAGFTSVGMDVFQFGPLPTPAVALMTRSLRADLGVMITASHNPYHDNGMKLFGPDGRKLDDKAELEIEALMDGSLVDGLAAPSDLGRAKRVDDAQARYVEIVKSSFPRAQRLSNLRLVVDCANGAGYKVAPAALWELGADVIPIGVEPNGFNVNEECGSTAPARLSKEVIKYRADLGIALDGDGDRVVLCDEKGRVIDGDQILGLLAGHWQDIGELRHPAIVSTVMSNLGLEQYLAGRGIALERTRVGDRYVSERMRETGINLGGEASGHIVMPDYSPTGDGLIAALQVLRVLGDSGKRASELLKVFKPAPQLLENVRVPRGRKPLESEAVKAAIAEAEVRMGVAGRLVVRASGTEPVVRVMAEGEQKLIRSVVDDVRGAIETVAQG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RECR_BURVG
Sequence: MKQPSALSSLVEALRALPGVGPKSAQRIAYHLMQHDREGAERLGRSLLFATEHLQHCEKCNTFTEAQICEVCSDDERDPTLLCVVETPADQIMLEQTMTYRGLYFVLMGRLSPLDGIGPKEIHFDRLVRRASDGVVKEVVLATNFTNEGEATAHYLGQTLKARGLAVTRLARGVPVGGELEYVDAGTIARAMLDRRTM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RLR91_PLAVT
Sequence: MVIPHIICLPMALHLWTCRFLSLGRPATNRRNCRRLRRRAVHRQATRPTRRIHHSAPQSFPQGLFNCAFVLLRRHALCRRLVGISTHVRAFKNCSKSDGPRRHKRTGQNSRVCPCGSWIYRIVSDRSGAFKCARRRVL
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 91.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Accumulates at the margin of the nucleolus, but is absent within it.
Protein: BRO1_ARATH
Sequence: MASSSLSNLMLAIHEKKTSSVDLYRPLRNYVTFTYSEREAQLIDDDLETLKQLRSDIERVSDPSPAARRDLLISYYKVLCLVETRFPISPDKDHVNAVSFVWYDAFKQKHKATQQNIHLEKAAVLFNLGASYSQIGLGHDRTTVDGRRQASHAFMAAAGAFAHLRDNESIKATIGPSTTVDVSVECVGMLERLMVAQAQECVFENTIAKGSTPGVSAKIARQVGIFYEEALSALIISPLKDHFDKGWISHVQLKAALFYGEACFRYGKELHEKEEIAEEIARLRSGASRLAEAKKSSRGAPAQLIEAMNTLESSINGNLDRAVKENDRVYLMRVPSPSSLSPLPAFSMVKPMNMTDILDASKEKMFSILVPDSSAKALSRYTEMVDDVIRTQAERLQQASELTRVRLKEMDLPDSILAVDGNSALPVDLKEDVEAVQISGGPAGLEAELQQLRDLKRVNQELLVHTEELLQKEATEDSQFRSQFGTRWTRPQSSTLTKNLQDRLNRFAANLKQAGESDVKIERSVRDNSALMSILDRRPIESAVPTLARPIMSLDATEDAIVGTLKQSLRQLENLGAQRAGLEDMLKEMKRKDDILPKLMTITGSYEDMFRKEISKYDHICEDISQNIEVQEQLLMQIQAQNEEFSTIFNLEDYKASKEKCYKQIQAAIMKYREIKENINEGLKFYVTLQDAITNVKQQCSDFVMTRSIQCRDMIEDVQRQMSGLSFQDHRSSGPYPSVHQPTASSPPPPPETQNPSHPHPHAPYYRPPEQMSRPGYSIPPYGPPPPYHTPHGQAPQPYPPQAQQQPHPSWQQGSYYDPQGQQPRPPYPGQSPYQPPHQGGGYYRQ
What is the function of this protein?
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles.  Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen (Probable).  Associates with FREE1 and ELC to perform function in the ESCRT-I complex.  Binds ubiquitin in vitro (PubMed:26902184).  Plays a role in the biogenesis of vacuole and multivesicular bodies (MVBs) (PubMed:26342016, PubMed:26324913).  Required for the endosomal location of AMSH3 (PubMed:26324913).  Mediates high-affinity phosphate transporter trafficking to maintain phosphate homeostasis.  Regulates vacuolar degradation of PHT1-1 (PubMed:26342016).
What are the official names of this protein?
Vacuolar-sorting protein BRO1, BRO domain-containing protein 1, AtBRO1.
What are the subcellular locations of this protein?
Cytoplasm. Late endosome. Endosome, multivesicular body.
Protein: TRPA_BUCAT
Sequence: MNRYQETFKRLSCLKEGCFIPFVVLGDPSLETSIKIIETLIKSGADALEIGIPFSDPLADGPTVQKSNLRALSKNNTFFEYFKILKQLRKKNKKLPIGILIYANLVYNQGIDNFYFQCFNSGLDSVLIADVPIEESKIFYNIANKYKINPIFICPPDADADFLYKISLYAQGFIYVLSRPGVTGIKNNTIALPRDFINKIKKYNSVPLLQGFGISNPKQIKEAISSGLSGVICGSAIINIIEKYLNQEKKMIKEIKKFTHLLKLSTKLE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TLP_PHAVU
Sequence: ANFEIVNNCPYTVWAAASPGGGRRLDRGQT
What is the function of this protein?
Has antifungal activity against C. comatus, F. oxysporum and P. ostreatus.
What are the official names of this protein?
Thaumatin-like protein.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL6_ROSCS
Sequence: MSRIGKKPIPVPRGVEVTIAEGNVVTVKGPKGTLIQRLPPEMIITHENGVITVARLSDQKQHRALHGLTRSLIANMVTGVTEGYQRVLEITGIGYRAVREGKNLILQVGFSHPIRVTPPEGITFEVMERRSANEPQQVIIRGIDKQKVGEEAAKLRALRPPEPYKGYGIKYREERVRRKAGKAGKAR
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PCEB_DESHA
Sequence: MNIYDVLIWMALGMIALLIQYGIWRYLKGKGKDPIPLQICGFLANFFFIFALAWGYSSFSEREYQAIGMGFIFFGGTALIPAIITYRLANHPAKKIRESSDSISA
What is the function of this protein?
May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA.
What are the official names of this protein?
Probable tetrachloroethene reductive dehalogenase membrane anchor protein.
What is the protein family that this protein belongs to?
Belongs to the PceB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YHAM_SHISS
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVRIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: VP4_AQRVC
Sequence: MGNVQTSVNTYNITGDGNSFTPTSDMTSTAAPAIDLKPGVLNPTGKLWRPVGTSVATIDSLAIVSDRFGQYSFVNEGMRETFSKALFDINMWQPLFQATKTGCGPIVLSSFTTTTSGYVGATAGDALDNPVTNGVFISTVQVMNLQRTIAARMRDVALWQQHLDTAMTMLTPDISAGSASCNWKSLLAFAKDILPLDNLCLTYPNEFYNVAIHRYPALKPGNPDTKLPDAQAHPLGEVAGAFNAATSEVGSLVGSSSTLSQAISTMAGKDLDLIEADTPLPVSVFTPSLAPRSYRPAFIKPEDAKWIAEFNNSSLIRKTLTYSGATYAVQLGPGPTRVIDMNAMIDSVLTLDVSGTILPYDTNPDLSTSVPAFVLIQTSVPIQQVTTAANITAITVVSAAGASAINLAINVRGQPRFNMLHLQATFERETITGIPYIYGLGTFLIPSPTSSSNFSNPTLMDGLLTVTPVLLRETTYKGEVVDAIVPATVMANQTSEEVASALANDAIVLVSNHLNKLANVVGDAIPVASKTDDSATSAIVSRLAVQHKLSQVGQTSPTPPDYPLLWRRAKRAASMFVSNPSLALQVGIPVLTQSGMLSALTSGVGTALRTGSLGKGVTDASEKLRARQSLTVAKQAFFDQIGSLWPGK
What is the function of this protein?
Interacts with VP7 to form the outer icosahedral capsid with an incomplete T=13 symmetry, about 80 nm in diameter, and consisting of 200 VP4-VP7 trimers.  Myristoylated N-terminal peptide may be released in the endosome and involved in permeabilization and delivery of transcriptionally active viral particles into the host cell cytoplasm (Potential).
What are the official names of this protein?
Outer capsid protein VP4.
What is the protein family that this protein belongs to?
Belongs to the aquareoviridae outer capsid VP4 protein family.
What are the subcellular locations of this protein?
Virion.
Protein: GLPB_ECO7I
Sequence: MRFDTVIMGGGLAGLLCGLQLQKHDLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYTLLGPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRSTWLSAPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADGKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERDGILEPILGLDVLQTATRSEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: ISPG_SHEDO
Sequence: MYSETPIKRRPSSRIYVGKVPIGDGAPIAVQSMTNTKTTDVEATIAQIRALEKVGADIVRVSVPTMDAAEAFKIIKQSVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEQRIRSVVECARDNNIPIRIGVNGGSLEKDLMDKYREPTPQALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVESYRLLAKQIRQPLHLGITEAGGLRAGSVKSAVGLGMLLAEGIGDTIRISLAADPIEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVINTVNELERRLEDLVTPMDVSIIGCVVNGPGEALVSHIGLTGGANKSGYYDDGVRQKERFDNLNLVDSLEAKIRAKASLMANRIAISDKTD
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GUAA_BACC3
Sequence: MIILKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFDLGLPIFGICYGMQLMTQQFGGTVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAGMSNEAKNLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFHMNVIKVDAKERFMNKLKGVEDPEQKRKIIGNEFIYVFDDEASKLEGMDFLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGIRVLGEITEEKLEIVRESDAILREEIIKAGLDREIWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPWDVLEKISVRIVNEVKHVNRIVYDVTSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: NOT_DROME
Sequence: MSETGCRHYQSYVKEHSYDTFRVIDAYFAACVNRDARERKAIHCNCFECGSYGIQLYACLHCIYFGCRGAHITSHLRSKKHNVALELSHGTLYCYACRDFIYDARSREYALINRKLEAKDLQKSIGWVPWVPTTKETNLLLANARRRLVRPNQTIGLRGLLNLGATCFMNCIVQALVHTPLLSDYFMSDRHDCGSKSSHKCLVCEVSRLFQEFYSGSRSPLSLHRLLHLIWNHAKHLAGYEQQDAHEFFIATLDVLHRHCVKAKAEHESKSNSSGSGSGTNSSNSSSSHCYGQCNCIIDQIFTGMLQSDVVCQACNGVSTTYDPFWDISLDLGETTTHGGVTPKTLIDCLERYTRAEHLGSAAKIKCSTCKSYQESTKQFSLRTLPSVVSFHLKRFEHSALIDRKISSFIQFPVEFDMTPFMSEKKNAYGDFRFSLYAVVNHVGTIDTGHYTAYVRHQKDTWVKCDDHVITMASLKQVLDSEGYLLFYHKNVLEYE
What is the function of this protein?
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA.  Catalyzes the deubiquitination of histone H2B, thereby acting as a coactivator in a large subset of genes.  Required to counteract heterochromatin silencing.  Controls the development of neuronal connectivity in visual system by being required for accurate axon targeting in the optic lobe.  Required for expression of ecdysone-induced genes such as br/broad.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase nonstop, Deubiquitinating enzyme nonstop, Ubiquitin thioesterase nonstop, Ubiquitin-specific-processing protease nonstop.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. UBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARCA1_RHIME
Sequence: MRTVGVHSEVGKLRTVMVCRPSLAHQRLTPGNCHDLLFDDVIWVHEAQKDHYDFVLKMEERGVEVLELHDLLSDTLIDAEARKFVLDRRVAPNVMGSQIAELMRPWMEEMDSRRLAAFLIGGISIADLPEGQGKALMASAFHSTQFVLPPIPNTLFQRDPSCWIYNGVTCNPMFWPARRAETLIQRAVYKFHPSFKGAAFDIWWGDSDEQFANATMEGGDVMPIGDGILLVGMGERTTYQAVGQVAKALFKAGAATRVIGCLMPKSRAAMHLDTVFTFCDRDVVTLFADVVDQIRCYSLFPLDDEGNFEVRQEDRPMLEVVAEALGVDKLRTIATGGNTYEAEREQWDDGNNVVALEPGVVVAYDRNTYTNTLLRKAGIEVITIRGSELGRGRGGGHCMTCPIWREPTD
What are the official names of this protein?
Arginine deiminase 1, ADI 1, Arginine dihydrolase 1, AD 1.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_COXBN
Sequence: MDEKIETRLIGATVQSNEPDLERSIRPKRLSDYIGQAAVREQMDIFIRAATNRREALDHVLIFGPPGLGKTTLAHIIAHEMQAGLKQTSGPVLEKAGDLAALLTNLEPHDVLFIDEIHRLNPAIEEVLYPALEDFQLDIIIGEGPSARSIKLDLPPFTLVGATTRAGLLTSPLRDRFGIVQRLEFYRIPDLIHIVKRAAHILNVVIDENGAGEIARRSRGTPRIANRLLRRVRDFAEVRANGMINESIAKEALDLLNVDIRGLDVMDRKLLETIIKKFQGGPVGIESLAAAISEERGTIEDVIEPYLIQEGFILRTPRGRIATELTYQHFKLPLPTQSTLQENFDLLGKVE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HIS7_DICT6
Sequence: MRRAEIERETKETYVKIALNLDGEGSFLGDFPIPYYKHLISTLCFYAGWDVEINAKGDIEVDPHHLIEDTGITLGKAFNSAILKSSFLRFSNKVIPMDEALVMVVVDISGRPYLEIKDDKEILKGRLIKEFLRGFVNNSQMTLHIWILSGENLHHVEEAIFKALGLALGEASKEVSNLKSTKGKIW
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_HAEIG
Sequence: MDKKSARIRRAARARHMMREQGVTRLVIHRTPRHIYAQVIAPNGSEVLAAASTVEKAIREQVKYTGNKDAAAAVGKAVAERALAKGVQAVAFDRSGFKYHGRVQTLADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y4847_RHOPB
Sequence: MADFLGMMKQAAQLQSKMKAMQEELEHIEVEGISGGGLVSVRMTAKMEVKTIKIDPSLINADEAGVLEDLLVTALADAHRKAESAMQEKMQALTGGLSLPPGLGL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein RPC_4847.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.