PharMolix/UniProtQA huggingface dataset:
Protein: PA2_DABSI
Sequence: NLFQFARMINKKLGAFXFXNYI
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RHLB_SALPB
Sequence: MSKTHLTEQKFSDFALHPQVVEALEKKGFYNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIDDRKVNQPRALIMAPTRELAVQIHADAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPAAQRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIESYIGHSIPVSKYNPEALMNDLPKPLRLTRSRPGNGPRRAGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACHA7_MOUSE
Sequence: MCGRRGGIWLALAAALLHVSLQGEFQRRLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDLQMQEADISSYIPNGEWDLMGIPGKRNEKFYECCKEPYPDVTYTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILLNWCAWFLRMKRPGEDKVRPACQHKPRRCSLASVELSAGAGPPTSNGNLLYIGFRGLEGMHCAPTPDSGVVCGRLACSPTHDEHLMHGTHPSDGDPDLAKILEEVRYIANRFRCQDESEVICSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.  The channel is blocked by alpha-bungarotoxin.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-7.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-7/CHRNA7 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=TMEM35A/NACHO promotes its trafficking to the cell membrane (PubMed:32783947). RIC3 promotes its trafficking to the cell membrane (By similarity).
Protein: RS6_PSEPG
Sequence: MRHYEIIFLVHPDQSEQVGGMVERYTKLIEEDGGKIHRLEDWGRRQLAYAINNVHKAHYVMLNVECTGKALAELEDNFRYNDAVIRNLVIRRDEAVTGQSEMLKAEENRSERRERRERPEHADSAEGDDSNDSDSSDNADE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: DRC4_TRYBR
Sequence: MPPRTAAERGGRRKSVKAPPPVDPLVELTTLESVHDALAKAERLRNYFQVERDKVNDFWTITKGEVETYRNRLFNAEASIEELERSHQVEMKVYKQRVRHLIYERKKKAQACQDESDRLLREAEDRHLQRMNEIQAKLQQQDQQLRAAAADHEMNVYEKRDSHSYMVTVTKTQSHEKELARLQVSCEAKLKVLRDELELRRRAEIHEIEERKNEHINALIKQHEEKFHEMKTYYNQITTNNLEIIHSLKEEIAQMKQNDEHNETLMYDIDRENQNLVAPLEEAQREVAELQQKRKQNEQNKRGLEVTRVKLRSLREEIRRQREEHQALEERYACVHREREELKGKFESALRQAVMVVEERNEVLQQKLIESHALVEERDVQLEGVLRAMNLEPKTLELIATEVDEWLQRKNQLIKDLHFELKKGEKLYSATLLEMERRCQTANIASLPRSNFE
What is the function of this protein?
Cytoskeletal linker that plays a central role in the flagellum cell motility.  Required for directional cell motility.  Plays a role as part of a dynein regulatory system that regulates flagellar beat in response to signals from the central pair apparatus and radial spokes in procyclic cells.  Also plays an essential role in the bloodstream form of the trypanosomes as its silencing is lethal for the circulating form.
What are the official names of this protein?
Trypanin, T lymphocyte-triggering factor, TLTF.
What is the protein family that this protein belongs to?
Belongs to the DRC4 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Note=Associated with the cytoskeleton. Localized to the site of attachment of the flagellum to the subpellicular cytoskeleton. Also localized in the flagellum of the bloodstream form trypanosomes.
Protein: YBX1_SCHPO
Sequence: MKAVYLDYLLRIRYTYVFNLKVSYQSERRTYGATEHFVGCLVPKAWNCLADDYTDIKTLLDLLFGVTAVIIFACTFKCFTMTEDGLTKLNLEAFLGVSGNTQELLESLGISAIPDLSNLGASNNNNSGLTFDPNDPSAAAFYIAQQVAAIEHPPPRKMTSSEKTRSENRERKKRWREQNEERNKDNDLRCRVNKKAKKLFGSEPSIEKTNWIEAEFTRRHTKRKEKERACLSQNQSSNASRANSQSLLPDLDLLATNSSANAVLQGSAINNALNALAKDPNLIHSLLTQIDFDPSKSKDGLNLGSLTDVVPPQPPQPEHELAALQEHNEAHDAAMRQYELERQQNAMLPGLASIDGLQALPHLDFSDSAVTNQSHSQSQNSLHPLISQSETHSIFSALSETPTPVSGNGNVADAPPDFSLSQVMPLDLIAPSMQPSAVSSPMSESHVQISSEMPRTGMSALPMRPRSQNVDKHRKFPYYNKRNAVTTPSSPYDGAQSGSPQFPPFELPPHNYSQAQSPNLATPSPSFSSLPDVSLPPIVKPNLMSEPTPTNSDEKSHALGFPPPPGQKIEFQRSSSKNGTAKSD
What are the official names of this protein?
Uncharacterized protein C17D1.01.
Protein: MYOZ2_HUMAN
Sequence: MLSHNTMMKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKMRQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNPDNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELPDYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTEPTDDTTVPESEDL
What is the function of this protein?
Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere.  Plays an important role in the modulation of calcineurin signaling.  May play a role in myofibrillogenesis.
What are the official names of this protein?
Myozenin-2, Calsarcin-1, FATZ-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the myozenin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Note=Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.
Protein: RK21_GALSU
Sequence: MTYAIIENSGRQFFTEPGKFIDINHIKAEVGDIIYFNRVLLLKSNNLIEIGYPFINNIKVKAKILKHFKDKKIRVYKMNPKKGTRKTKGYRSLCTRVLIESIENTENIIN
What is the function of this protein?
This protein binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L21, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1239_BARBK
Sequence: MNDMTNIMKKAKEMQQKMQQIQDEMVNLKVTGTAGGGLVSITLNGQNIISEVKIDPSLIKPEESEILEDLIMAAHNEAKEKISTAMAEKTQNITAGLPIPPGFKLPFS
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BARBAKC583_1239.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL20_CLOPS
Sequence: MARVKRAVNARKNHKKVLKLAKGYYGGKSKLFKTANESVIRALRNAYVGRRLKKRDYRRLWIARINAATRMNGLSYSRFMNGMKLAGVDINRKMLSEIAINDPKAFADLVELAKKHLNA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: HEM1_PROM0
Sequence: MHIVVVGLSHRTAPVEVREKLSIPDQSITESLKALKAFSDVLEVSILSTCNRLEIYALVKDKNTGISSIKEFISEYSGIIFDDLNPHLFCFRQEEAVLHLMKVSAGLDSLVLGEGQILSQVKKMMRLGQENQSTGPILNRLLTQSVSTGKKVRSETNLGTGAVSISSAAVELAQLKIGQEKGFDNLVSLESENVLVVGAGRMSRLLITHLKSKGCHKLILLNRNIDRALNLAQDFPDLEIVCKGLNELEENISLSSLVFTSTASEEPIIDLTKIEKINLSNRLKFIDIGVPRNISNDVKQHEFVKSFDVDDLQEVVSRNQEFRQKIAKEAESLVEEERIIFLEWWASLEAVPVINKLRSDLELIRKEELQKALSRMGPDFSARERKVVEALTKGIINKILHTPVTKLRSPQSREERQVSLKIVEKLFSLVEEDKNN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PGK_SHIBS
Sequence: MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVNDVKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGX_ECOSE
Sequence: MTRLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: RS21_BRUC2
Sequence: MQVLVRDNNVDQALRALKKKMQREGIFREMKMRGHYEKPSEKRAREKAEAVRRARKLARKRAQREGLIGGRTGAR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RPOC_STRPQ
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQEYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFNKSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDAGREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKILFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQNIQEVIDGLDINVPFKKKNLGNIIAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVEEINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEVRLQGRYTRKSVKHPETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAVITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEGSIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGDTDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSAEAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: YBEY_TROW8
Sequence: MTGLLYLQNSSGYNDCYFKTESLVDFLYRTLFIDKGSYLGVSFITAAEMRDLKIKHFGVNEDSDVLSFPIDEIAPGSENSLVYGVLGDIVVCPETVMRQAVRHPFEHEIYLLVVHGFLHLLGFDHSDAPSKKEMFSLQAKLIEDFFALENLGTPSEEITITPDLRPSLGRI
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_ECODH
Sequence: MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: LPXD_HAHCH
Sequence: MGKTDLSYTLADIAFRIGAELRGDGSVEVKGLATLQKAQAGQISFLANKNYLKHLKDTCASAVIIPSSFADQCSTNVLVMENSYFGYALCSQLFSPQWWSMSGISPSAAISESAKLGAGVTIGANVVIEEDAEIGEGAVIGPGCYIGAGSIIGAKTQLRPNVTVYHGVNIGARALIHSGAVIGSDGFGFAPNKGDWAKIAQLGGVVIGDDVEIGANTTIDRGALDDTVIETGAKLDNQIQIAHNVKVGAYTVIAACVGVSGSSSIGKHCMIGGGVGIAGHLEITDQVQITGMTLVTHNIKEPGVYSSGTAVEPNASWRKNVARFRQLDQLARRVRVLEQGGRRKSDAD
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: SLSS_SOLLC
Sequence: MGTLRAILKNPDDLYPLIKLKLAARHAEKQIPPEPHWGFCYLMLQKVSRSFALVIQQLPVELRDAVCIFYLVLRALDTVEDDTSIPTDVKVPILISFHQHVYDREWHFACGTKEYKVLMDQFHHVSTAFLELGKLYQQAIEDITMRMGAGMAKFICKEVETTDDYDEYCHYVAGLVGLGLSKLFHASGKEDLASDSLSNSMGLFLQKTNIIRDYLEDINEVPKCRMFWPREIWSKYVNKLEDLKYEENSVKAVQCLNDMVTNALSHVEDCLTYMFNLHDPAIFRFCAIPQVMAIGTLAMCYDNIEVFRGVVKMRRGLTAKVIDRTKTMADVYGAFFDFSCMLKSKVNNNDPNATKTLKRLDAILKTCRDSGTLNKRKSYIIRNEPNYSPVLIVVIFIILAIILAQLFGSRS
What is the function of this protein?
Converts farnesyl diphosphate (FPP) into squalene, a precursor for sterol biosynthesis in eukaryotes.
What are the official names of this protein?
Squalene synthase, SlSS.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: K2C7_BOVIN
Sequence: MSLHFGSQVFSSRSAAFPGRGTQVRLSSVRPGGFGSSSSLYGLGASRPRVAARSSYGAPVGTGIRAVTINQSLLTPLQVDIDPSIQQVRQEEREQIKTLNNKFASFIDKVRFLEQQNKLLETKWALLQEQKSAKSNRLPGIFEAQIAGLRKQLEALQLDGGRLEVELRNMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDVAYMNKVELEAKVDTLNDEINFLRTLYEQELKELQSEVSDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIANRSRAEAEACYQTKFETLQAQAGKHGDDLQNTRNEIADMNRAVQRLQAEIDSVKNQRSKLEAAIADAEQRGELAVKDARAKQEDLEAALQKAKQDMTRQLREYQELMNVKLALDIEIATYRKLLEGEESRLTGDGVGAVNISVVSSTGGSGSLLTFGGTMGNNALRFSSGGGPGTLKAYSMRTTSATSRSPRK
What is the function of this protein?
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.
What are the official names of this protein?
Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Type-II keratin Kb7.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RSMG_CHLTE
Sequence: MQNDLHLLEGLCRQHGIPVTKNALTLLVRYARLLEAWNLKVNLVSRKEHAPVIVKHVFHSLLIARIHDFKPGETVLDLGTGGGLPGIPLAILFPETSFLLVDSTGKKIAACKAMIKELGLENVIALHSRVEELKGVIFDTVLSRQVAPLEELCAYSARLLKHDGVLICLKGGSLNEEIAEAVLSREKHLGFPASVDQLPIGEIDPMFSEKQIVIARW
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSA_LATSS
Sequence: MMKKWLLAAASLLMVVTLAGCGSNTIATLKGGKVTQDEFYKEIKETSAGKQQVQQMILQKALQEQYGSKSLTKKIDKTYNTYKKQYGSSFTSVLAQSGLTTSSFKNQITTQMLANAALKANKKVTNADLKKQWKTYEPKVEVQHILVEKKDTAETVISELKKDNSTKNFTALAKKYSTDTGTKKDGGKLPVFDSTDTSLDPTFKTAAFKLKTNEYTTTPVKTSYGYHVIRMIKNPGKGKMADHKKTLTDQVYAKWANDQTVMAKVYTKVLKKADVTIKDKDLSDILSSYGVNAKKSSAKSSSK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: LACG_LACCB
Sequence: MSKQLPQDFVMGGATAAYQVEGATKEDGKGRVLWDDFLDKQGRFKPDPAADFYHRYDEDLALAEKYGHQVIRVSIAWSRIFPDGAGEVEPRGVAFYHKLFADCAAHHIEPFVTLHHFDTPERLHEAGDWLSQEMLDDFVAYAKFCFEEFSEVKYWITINEPTSMAVQQYTSGTFPPAESGRFDKTFQAEHNQMVAHARIVNLYKSMQLGGQIGIVHALQTVYPYSDSAVDHHAAELQDALENRLYLDGTLAGEYHQETLALVKEILDANHQPMFQSTPQEMKAIDEAAHQLDFVGVNNYFSKWLRAYHGKSETIHNGDGTKGSSVARLQGVGEEKLPDGIETTDWDWSIYPRGMYDILMRIHNDYPLVPVTYVTENGIGLKESLPENATPDTVIEDPKRIDYVKKYLSAMADAIHDGANVKGYFIWSLQDQFSWTNGYSKRYGLFFVDFPTQNRYIKQSAEWFKSVSETHIIPD
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: HBA_OTOBE
Sequence: VLSPADKTNVKASWEKLGGHGAAYGAEALERMFLSFPTTKTYFPHFDLSHGSAQLQGHGKKVADALANAAAHVDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPADFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RIMP_HELP2
Sequence: MTKRIEEKIEGVIESLGYLLYDVSLVKENEHNILRVSLKNPNGAVSLDICQQVSEIISPLLDVCDFIQDAYILEVSSMGLERVLKTPKHFKLSLGEKVEVKLTNKESFQAVLKDANDWSADFELENHAIKSVEYKDLKKVKTLFEW
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPA9_CAEEL
Sequence: MYFHSTAIILFLNKIDLFEIKITHTNITVAFPDYEGPRERDCALEYIRVQFISLNNNKNRKIYQHVTSATDTARIQVVIDMLFDIIISASLKMVGV
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (By similarity).  Plays role in innate immunity and maintaining survival in response to metabolites of E. coli (PubMed:21108728).  This might be by regulating the expression and signaling of genes such as lys-8, ins-7 and daf-28 (PubMed:21108728).  Has a role in lifespan to promote longevity (PubMed:17187771, PubMed:21108728).
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-9 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: I1B2_CONST
Sequence: GCKKDRKPCSYQADCCNCCPIGTCAPSTNWILPGCSTGPFMAR
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels.  Produces general excitatory symptoms (By similarity).
What are the official names of this protein?
Iota-conotoxin-like S11.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYC_CHESB
Sequence: MSDGFKALKLYNTLTRRDEEFVPLDPANVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRQLYGDDHVTYVRNITDVDDKINARALRDFGEDITAGRLTLNEAIRRVTERTAAQFHADVAALGCLAPTHEPRATEFVLPRTDGKADMASLIQTLIDRGHAYAAKGEILFDTASMPDYGQLSKRRLEDQQAGARVAVDPHKRNPSDFVLWKESSAEEPGWEGRFTFEGKPLVIRGRPGWHIECSAMSAAYLGEVFDIHGGGLDLIFPHHENEIAQSRCAHGTPVMANYWLHNGFVQVEGKKMAKSEGNFVTIHDLLATENFGGRKWPGEVLRLAILMTHYREPLDFSLRKLEEAEAVLDGWYRVVGDAKHQEGDSGAVRRALLDDLGTPAAITVLHDLRAQAARGSEAAKADLKANAVLLGLLTQSQDQWFSGKAADAAIDEAAVEERVAARLSLLRAKNFPEADRIREELSGRGIQLMDYKDPETGERRTKWEVKR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_IDILO
Sequence: MALTKAELAEVLFDKYGVSKQDAKVLVEDFFEEIRVALERGEQVKLSGFGNFELRTKNQRPGRNPKTGEEIPISARRVVTFKPGQKFKSRVENAEPED
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: GLUQ_PSEF5
Sequence: MTASTSSSYIGRFAPTPSGYLHFGSLVAALASYLDARAVGGRWLLRMEDLDPPREEPGAQAAILKALESYGFEWDGQMIRQSDRHDAYGEVLNRLFQQGLAYACTCSRKQLEPYHGIYPGLCRNLGHAQDDAAIRLRVPELEYRFVDRVQGEYRQHLGREVGDFVIRRRDGLYAYQLAVVLDDAWQGITDIVRGADLLDSTPRQLYLQELLGLSQPRYLHVPLITQPDGHKLGKSYRSPPLTEDQAPPLLLRALRALGQKPPADLDGASVAQIMAWGMAHWDAALIPRTLSVPEAQLS
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: KYNU1_ASPOR
Sequence: MGSRLHVQEIKKGPPLPFKDDIRAFTREYAESLDAQDPLRHFRDEFIIPSKKDLKRKTLNANENIEDSSDPRSIYLCGNSLGLQPRNTRKYLEHYLRTWAIKGVTGHFTPHDDQLLPPFVDVDDAGAKLMAPIVGALESEVAVMGTLTANLHFLMASFYQPTKEKYKIILEGKAFPSDHYAVESQIQHHNLDPKDAMVLIELENLDRPILDTEKILRVIDEHASSTALILLSGIQFYTGQYFDIEKITAYAHSKGIIIGWDCAHAAGNVELKLHDWNVDFAAWCNYKYLNSGPGGMAGLFVHENHGRVDMTKVGSKDEPFRPRLSGWWGDDKKTRFRMENRFVPQPGAAGFQLSNPSVLDMNAVAASLEIFNRTSMAEIRKKSLDLTGYLEHLLLKYPLDAAPEDKPFSIITPSNPAERGAQLSLRLGPGLLDNVLEVLEENGVVIDERKPDVIRVAPAPLYNTYADVWQFCQIFFDACQKAVRARK
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase 1, Biosynthesis of nicotinic acid protein 5-1, L-kynurenine hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.