PharMolix/UniProtQA huggingface dataset:
Protein: RSMH_SULSY
Sequence: MVEHYSVLHKEVLEFSKLIEGEVFVDATVGGGGHSYLILKQNLNLKLIGLDKDDYALKVAKERLKEFEDRITLVKSSFKDLDKVLQSLQIKEINGILFDFGVSTFQLKLERGFSFQREEFLDMRMDTTQKLTAYDIVNYYREQDLYNIIKTYGEEKFASKIAKSIVEYRKKKKIETTKELADIVYRCYPPNLRHGKIHPATRTFQAIRIEVNNELKDIEEGLEKAINLLAKNGIIMAISFHSLEDRIVKNMFKKYKELKFLEILTKKPITPSDEEIKENPASRSAKLRVGRRI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCPC_MACPY
Sequence: MKSAIMAVASAAPGLRGPSAFNGAALTTSAKSSSAMKMSFESEIGAQAPLGFWDPLGLLEDADQDAFERLRYVEVKLGRIAMLAIAGHLTQQNARLPGMLSNSANLSFADMPNGVAALSKIPPGGLAQIFGFIGFLELAVMKNVEGSFPGDFTLGGNPFASSWDAMSAETQASKRAIELNNGRAAQMGILALMVHEELNNKPYVINDLLGASYNFN
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.  Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
What are the official names of this protein?
Fucoxanthin-chlorophyll a-c binding protein C, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fucoxanthin chlorophyll protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein. Note=FCPs are probably transported across the endoplasmic reticulum membranes that surround the plastid via a signal peptide, followed by translocation across the thylakoid membrane via a transit peptide.
Protein: PROA_SORC5
Sequence: MEQSNIDLEGALRALCQRARTAARALAPLDRAQKDRALRAIAERLRAEAGEGKRSAVLAANAEDVAAARAAGVSEALVDRLVLDEARLAAIAGAVLEIAAASDPVGQVVGMERRPNGLLVGQVRVPLGVIAMIYESRPNVTVDAAVLCLKSGNAAILRGGKEAARSNAALGELISDALRSVGLPADAVQMVPSLDREATRILLGLTGMIDLAIPRGGEGLIRFVAENARVPVIQHYKGVNHLYADAGCDLEMACRLVENGKLQRPGVCNALECLLVHEDVAAPLLGRVAALSERGLELRGDAATCALVPSARKAAEDDYGREFLAPILAVRVVRSLDEAIEHIGRYGSMHTEVICTPRYDHAQRFLREVDASCVLVNASSRFNDGGELGLGAEIGISTTKLHAYGPMGLASLTTLKWIAYGEGQTR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYF6_CHICK
Sequence: MMMDLFETGSYFFYLDGENGALQQLEMAEGSPLYPGSDGTLSPCQDQLPPEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTDRRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQQDKMQEVAADPFSFSPKQGNVPGSDFLSTCGSDWHSASDHSRALGGSPKAGGSMVESSASSSLRCLSSIVDSISSDEPKLPGAEEAVEK
What is the function of this protein?
Involved in muscle differentiation (myogenic factor).  Induces fibroblasts to differentiate into myoblasts.  Probable sequence specific DNA-binding protein.
What are the official names of this protein?
Myogenic factor 6, Myf-6, Muscle-specific regulatory factor 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: KHSE_STRP2
Sequence: MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQIGKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLGQLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIPNYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYRQDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHDLRVDTQGVRVEAK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_STRM5
Sequence: MNPNYLDFEQPIADLEAKIQELRNASAGPAVNVEAEVHALQDKLRLRTAQIFRNLTSWQVLQLARHPSRPYTADYLRVMFDEFQELAGDRAFADDKAIMGGLARINGRSVMVIGHQKGRDTKEKIKRNFGMPKPEGYRKALRLMKMAERFGLPVLTLIDTAGAWPGIDAESRGQSEAIARNLIEMAELKVPIICTVIGEGGSGGALALGVGDRTVMLEYAVYSTITPEGCASILWKDAGKAKDAAEQLGLTAPRLKSLGLVDKVVREPTGGAHRNPTQMAKRLKAVLLNELDALEKLSTEQLLEQRYTRLRSYGTYEAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIGI2_ACET2
Sequence: MIDLFSPKGKKDTVSTTNKDKSFEDGIVNIINKIKAGDKLLREEFINSYTPYIIRTVSNLTGKYVDVENSDEFSVGLAAFNEAIDSFDEGKNMFFFKFSTLVIKRRLTDYARHNKKHCHVYPFTYFEDKNNSYFEQIHLKSEIDLQNTYEISREIELYEQKLRDFGISLEHLAKCAPKHKDSKSLCIKIAKVIADNKELFSKLERTRNIPKTELLKLLKINKKTIERNRTFIIAAALIFGNDFNLLKDFLDISEPGGDNIERSTK
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity).  This sigma factor is involved in regulation of cellulosomal genes via an external polysaccharide-sensing mechanism (Probable).
What are the official names of this protein?
RNA polymerase sigma factor SigI2.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. SigI subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENL02_ARATH
Sequence: MTFLKMKSLSFFFTILLSLSTLFTISNARKFNVGGSGAWVTNPPENYESWSGKNRFLVHDTLYFSYAKGADSVLEVNKADYDACNTKNPIKRVDDGDSEISLDRYGPFYFISGNEDNCKKGQKLNVVVISARIPSTAQSPHAAAPGSSTPGSMTPPGGAHSPKSSSPVSPTTSPPGSTTPPGGAHSPKSSSAVSPATSPPGSMAPKSGSPVSPTTSPPAPPKSTSPVSPSSAPMTSPPAPMAPKSSSTIPPSSAPMTSPPGSMAPKSSSPVSNSPTVSPSLAPGGSTSSSPSDSPSGSAMGPSGDGPSAAGDISTPAGAPGQKKSSANGMTVMSITTVLSLVLTIFLSA
What is the function of this protein?
May act as a carbohydrate transporter.
What are the official names of this protein?
Early nodulin-like protein 2, AtENODL2, Phytocyanin-like protein ENODL2.
What is the protein family that this protein belongs to?
Belongs to the early nodulin-like (ENODL) family.
Protein: NCAP_GTOVV
Sequence: MAHSKEIPSFRWTQSLRRELGMFTEPTKSSVLNDAKLIADSLDFTQVSQVQRLLRKSKRGDTDLDKLRDLNKEVDRLMSMKSVQNNTVLKVGDLGKDELMDLASDLEKLKKKIGDRESNSPRMYMGNLTQSQLEKRAGILRTLGFQQQRGAAGGVVRLWDVSDPSKLNNQFGSMPALTIACMTVQGGETMNNVVQALTSLGLLYTVKYPNLDDLEKLTLEHDCLQIITKDESALNISGYNFSLSAAVKAGASLIDGGNMLETIKVTPNNFSSIVKAALNVKRREGMFIDERPGNRNPYENLLYKLCLSGEGWPYIGSRSQILGRSWDNTSVDLNARPVTGPRAPEKNGQNIRLSNLSEMQEAIVKEAMRKLDSSDTIWMDIEGPPTDPVELAVFQPSSGNYVHCFRKPHDEKGFKNGSRHSHGILLKDLEDAQPGLLSYVIGLLPQGSVITVQGADDIKKLFDIHGRKDLKLVDVRLTGEQSRIFEQEVWEKFGHLCRAHNGVIVPKKKNKEANSTKEPHCALLDCIMFQSVLDGHLPDTIPIQLLPNTLVFQAKSAFVM
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CCNB1_HUMAN
Sequence: MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSALVQDLAKAVAKV
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: YHDC_SCHPO
Sequence: MSTMEEEKVISKSTSVDISEGTFDDITIEKKEEAKLVRKLDWYLMPMFSVLYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSAAVSVFYATYITAETPSVLLVKKFGPHYYLSAMIIGWSLVTIFTCFVRHYWSLVLTRLLLGICEGGFFPCLSLYISMTYKREEQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGLPNWGWLYIIEGLISAISALWILFCLPDDPSTARFLNPREKELMKIRAEQRQKYMGSPNFDWTQFRKAFKDPKMYMSCVIQFCQDLVLYGISTFLPSILKLELGYSSLAAQYMSVPVYALGGISVYVICLLSDRTNIRGWFIIGMNFFGLAGFIILLATTNSAANYVATYLIALPLYPTVALNITWINNNMAPHYRRATALGCNQTIGNLAGVIAGQVYRSSPYKLGHGFALGCTVVGTLTATAMRFYLQRQNKIKQEILNGERVDEKKERDGCDALDFVYVL
What are the official names of this protein?
Uncharacterized transporter C1683.12.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Allantoate permease family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Protein: Y457_ANAVA
Sequence: MGRNFQSETRIAGFITKRDVILGGLRTGAIFGSLFGSFLSLLTGVGVLFIPFVGPIVAAGPISALLLGAASGAIAGSAGAGLVSVLTTLGMPEEKAAIYQTRLQAGEFLLLTEVPSDRAGEFQLLLESAGAEELSTIDKTLARPCPGPCKSPEDLSPEVRSHLSSEAQSTFIERYNGVLNETTDEFTAEQAAWEAVHQKFDEDENGVWSKAKVGV
What are the official names of this protein?
Uncharacterized low temperature-induced protein all0457 homolog.
Protein: KAD_SALTY
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIVVDYVLEFDVPDELIVDRIVGRRVHAASGRVYHVKFNPPKVEGKDDVTGEDLTTRKDDQEETVRKRLVEYHQMTAPLIGYYQKEAEAGNTKYAKVDGTQAVADVRAALEKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 042L_FRG3G
Sequence: MFAPPSSLFVPATAPAPSTSGFTIPANLRRDAYVCPFATAEKERKEREQQQPASKGLNHDLAAQEPLHPSLVSRFPSNYRGSFLR
What are the official names of this protein?
Uncharacterized protein 042L.
Protein: Y1019_STAAN
Sequence: MSEIKRLEINYKTDELFENFRAFGNKDLYMVNELNGQMIDASSDSPFYGIFVGDQLGARMALLKKGDVEEIYFPDFEDYILLWKLEVLPKYQNRGYASELIDFAKSFNMPIKAIGRNDSKDFFLHHGFTDVEAKNIEGHDVLLWKP
What are the official names of this protein?
Uncharacterized N-acetyltransferase SA1019.
Protein: CYAY_BURTA
Sequence: MSDTDYLTRAEAVLAAVERSVDAANDGDADVDLERNGSVLTLTFENGSKIIVNLQPPMKEVWIAAKAGGFHYRFVDGAWRDTRSGDEFFAALTGFATQQAGMPIAFSA
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: BIOB_ACICA
Sequence: MTLRNDWTRDEIQALYDQPFLDLVFEAQSVHRQHFQANTIQVSTLLSIKTGKCPEDCKYCSQSAHYDSKLEAEKRIAVDKVISEAQAAKESGSSRFCMGAAWRNPHERDMPYVLEMVREVKALGLETCMTLGMLNQSQAERLKDAGLDYYNHNLDTSREYYSHIISTRTFDDRLNTLDHVRHAGMKVCSGGIVGLGESRNDRIGLLQELATMPVHPESVPINMLVPIEGTPLAEVEKLDVTEWIRTIAVARIIMPHSYIRLSAGRESLSDSDQALAFMAGANSLFSGEKLLTTPNAGEGKDQILFAKLGLTAEKAKPTVAELSVDAMSA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: AATM_RAT
Sequence: MALLHSGRVLSGMAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAGKNLDKEYLPIGGLADFCKASAELALGENSEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEMAAVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK
What is the function of this protein?
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA).  As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance.  Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism.  Facilitates cellular uptake of long-chain free fatty acids (By similarity).
What are the official names of this protein?
Aspartate aminotransferase, mitochondrial, mAspAT, Fatty acid-binding protein, FABP-1, Glutamate oxaloacetate transaminase 2, Kynurenine aminotransferase 4, Kynurenine aminotransferase IV, Kynurenine--oxoglutarate transaminase 4, Kynurenine--oxoglutarate transaminase IV, Plasma membrane-associated fatty acid-binding protein, FABPpm, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Cell membrane. Note=Located in the mitochondria of liver, pancreas, spleen, heart, pituitary gland and submandibular gland cells. In kidney, located in the mitochondria, on the cell surface of regions with protrusions in distal tubules, on the apical cell surface of protrusions along the microvilli in cortical collecting ducts, in condensing vacuoles, on the cell surface at cell boundaries of adjoining kidney cells and on the cell surface of endothelial cells lining capillaries in the glomerulus. Also located at the cell surface of endothelial cells lining arterioles and on the cell surface of lymphocytes.
Protein: IBPA_SERP5
Sequence: MRNFDLSPLYRSAIGFDRLFNALEAGQSQGNGGYPPYNVELVDENHYRIAIAVAGFAEQELEITTQDNLLIVRGAHNNEPAERTYLYQGIAERNFERKFQLAEHIQIKGAKLENGLLYIDMERIVPETLKPRRIEIK
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_EDWI9
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLNKVENIVREEMNYAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGDRPFVLGPTHEEVITDLVRNEISSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTTQESLQETYEAMYAAYSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGEDDIVFSTASDYAANIELAEALAPATGRAAANQPMQLVNTPDARTIAELVEQHGLPIEKTVKTLLVHASEESGHALVALLVRGDHELNEVKAEKLALVASPLTFANEAEIRALVNAGPGSLGPVNLPLPIVADRAVAAMSDFGAGANIDGKHYFGINWERDAALPQIADIRNVIEGDPSPDGKGTLLIKRGIEVGHIFQLGTKYTEALNATVQGEDGRNQLMTMGCYGIGVTRVVAAAIEQNHDERGIIWPDAIAPFQVAILPMNMHKSFRVKEVAERLYDGLRAKGIEVLLDDRKERPGVMFADMELIGIPHTIVIGDRNLDNNEIEYKYRRSGDKLMISVDEIEAFLQAQIAR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_PSEAB
Sequence: MAIKLEDKKAIVAEVNEAAKAALSAVVADARGVTVGAMTGLRKEAREAGVYVKVVRNTLLKRAVEGTQFDVLNDVFKGPTLIAFSNEHPGAAARIFREFAKGQDKFEIKAAAFEGQFLAANQIDVLASLPTYDEAVSQLMSVIQGATSKLARTLAAIRDQKEAAAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: YPTV2_VOLCA
Sequence: MARIPGRPDYDALIKLLLVGDSGVGKSCLLLRFTDDMFTSSFITTIGIDFKIKKVDVDGKLVKLQIWDTAGQERFRTITSAYYRGAQGIILVYDITDEASFNNVRNWMRNIEQHASDNVNKILVGNKLDLAEDKRVVSIARGQALADEFGFRFYETSAKDNVHVEEAFIAVAKDVLARMEGEHANQQLLQQQQLSAAQPVRLTSGSPSPAQGKSCCR
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
GTP-binding protein yptV2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: TOP1_STAAN
Sequence: MADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSNCDYKEAAQK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: ATG22_NEUCR
Sequence: MAKISGLCVFKWYPLYAYQCPATGPSVQLKYSAMTPRHNNNVNHVYNGPDIQWEDESLRPPPAPRLFSRSSYASYASKASKRSFYSYTSSCFEADDERSDTLSFADWITTTMSGRMSPANAGDNSDSYPYGDDTDGDSSSGLPPPRYPGDDTRPTSQKELAGWYAYAFAAEVYVICGIGSFIPILLESLARENGVLLSDRSKPCGSSSDKHTTSAEGQCVVYVLGMEINTASFAMYTFSVSVLLQALLVVSISCAADHGNFRKKLLLAFAWIGSACVMAYIFISKSTYLIGALLAIISNTSFGASFVLLNSFLPLLVRHHPEIDQVGDYGSPGYATTEEGDDEDDEYQEDSTRNSTTALLGSRRYEEGEPLSRVQTTEELTSRELELSTQISAKGIGIGYIAGLFLQCVAIAILITLKNTTWSQRIVLCVIGAWWAIFTIPAAMWLRPRPGPPLPTKSNTGGIRALFHYTIYAWKSLFRTIHLARRLVDIVLFLAGWFLLSDAIATTSSTAILFAKTQLHMEPWALGMINVISTASGILGAFSWSFISRKFRLKAHQTILACIALFELIPLYGLMGYLPFVQAWGVGGLQQPWEMYPLAAIYGFVLGGLSGYCRSLYGELIPPGSEAAFYALYAITDKGSSVFGPAIVGAIIDASGEIRPAFWFLAAIVGTPALFIWFINVERGRTEGEALAEIIEGFKMNGQNGLNGNGADGLADDRRGSDASRAILGRYDDEDEE
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: ATPD_CLOBH
Sequence: MYEYLDRRYALALYEVAEENNKVDEYLRDLKEVVNIIKNSEDICKILKHPEINTSRKKEIFTELFKDKVDDKILSFLLVLIEKDRILYLEEKLKEMEKIYLEKNNMILANIKTVIPLLKEEREELIEKLGNKYNKKIILEEEIDKSIIGGVYVRVGDDVLDGTLSTRLKDIKKMMLKRE
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: OTC_AGRFC
Sequence: MASPKHFLDLSAVGPQDLRTILDDARARKVATKAGTAEKPLAGKMLAMIFEKPSTRTRVSFDVGMRQLGGETLFLSGTEMQLGRAETIGDTAKVLSRYVDAIMIRTTDHSRLLELAEHATVPVINGLTDDTHPCQIMADIMTFEEHRGPVKGKTIAWTGDGNNVLHSFVEGSARFGYRMTMAVPMGSEPHDKFMNWARNNGGEIALYHDADKAVAGADCVVTDTWVSMNQEHKARGHNIFQPYQVNEALMAKAQKDALFMHCLPAHRGEEVTDAVIDGPQSVVFDEAENRLHAQKSVIAWCMGVI
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_METHJ
Sequence: MKAVCLLSGGMDSSTLACLAKHDGYDILALHFSYGQRTEEKERECAKRIARHLNALEFLEVDLTYLKAVGASSLTDYAMQVKAHEDAGDGIPDTYVPFRNANLLSVATSFAEARGADAIYIGVQASDYSGYPDCRPEFIDAFQKVITLGTRPDAGIILKTPFVKLNKAEILKIGMDLNVPYEDTWSCYAENEVACGICGSCHYRLEAFRQIGIQDPIPYR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, Archaeosine biosynthesis protein QueC, PreQ(0) synthase.
What is the protein family that this protein belongs to?
Belongs to the QueC family.