PharMolix/UniProtQA huggingface dataset:
Protein: TRAM5_ECOLX
Sequence: MAADDKIEELIREIAAKHGIAVGRDDPILILQTINMKLMQDSASAQQEILDAFKSELESIAHRWGDDAKGKAERTLNAALAASKDAMTRGMQEGAKAAAEAVRREVEAVTAQLVAPIREARRVAMMNMVAAGMAVVAAGLALWASL
What are the official names of this protein?
Protein TraM.
What is the protein family that this protein belongs to?
To plasmid IncP-alpha RP4 TraM.
Protein: RS15_XYLFM
Sequence: MSIDTQSIIENNKRSAHDTGSPEVQVALLTARIELLTKHFKIHKKDHHSRRGLLQMVNRRRSLLDYLNKKDNERYKLLIEKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ENV_AVISU
Sequence: VAAAQALREIERLACWSVKQANLTTSLLGDLLDDVTSIRHAVLQNRAAIDFLLLAHGHGCEDIAGMCCFNLSDHSESIQKKFQLMKEHVNKIGVDSDPIGSWLRGLFGGIGEWAVHLLKGLLLGLVVILLLVVCLPCLLQFVSSSIRKMIDNSLGYREERKKFQEAYKQPERVV
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the Alpharetroviruses envelope glycoprotein family.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single- pass type I membrane protein. Host cell membrane; Single- pass type I membrane protein.
Protein: AROB_COXBN
Sequence: MKTERVNVNVNNQPYPIYIGENLLQDKSLLQRHVKGRQVMIVSNETIAAFYLDPLKAIYQDFQCDTFILPDGEQYKTLEYWERILHKLACNHHRDTTLIALGGGVVGDITGFAAACYQRGVDFIQVPTTLLAQVDASIGGKTAVNHPVGKNLIGAFHQPKAVIIDLNTLNTLPEREFKAGMAEIVKAALIKDEKFFTDLENKMSDLLQRNFIFLQAVIKRAAEIKRDIVNADEKERSGERALLNLGHTFAHAIERLLGYGQWLHGEAVSAGLVLAAQLSHRKNLLDFESLQRICRLLTQISLPIHFPKSINADELLSAMYMDKKVANERLHLILLEDLGHAVVSDQVDDRELKSFLENG
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S2534_BOVIN
Sequence: METVPPAVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQKRGTYPRLYRGFVASVVAVVRADGLCGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLSQQPGGTVVAGAVAGALGAFVGSPAYLVKTQLQAQTVAAMAVGHQHHHESLLGALETIWRQQGLAGLWRGVGGAVPRVMVGSAAQLATFASAKAWVQERQWLPEDSWLVALAGGMISSIAVVAVMTPFDVVSTRLYNQPVDGAGRGKLYGGLTDCLVKIWRQEGPLALYKGLGPVYLRLGPHTILSMLFWDELRKLAGWGQHQGS
What are the official names of this protein?
Solute carrier family 25 member 34.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BPT_CERSK
Sequence: MRHTLPIAPQFYVTAPQSCPYLEGRLERKLFTALQGEHAQKLNDTLSKQGFRRSQNVLYRPSCAECSACLSARIRVADFEPTRTQRRVMKRNADLRRNATSPWATEDQYALFRRYLDDRHADGGMADMDIFEFAAMIEETPIRSRVIEYSRPGDTPSNRPLSAVCLTDIFDDGLSMVYSFYDPDLAGRSLGAYVILDHIEIAREAGLPYVYLGYWVPGSRKMGYKASYSALEIYKGGRWQDIGQPSDHRAELHPLSVDPIAEQVARISLPEARSGDRSRD
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR8J2_HUMAN
Sequence: MASGNLTWVTEFILVGVSDDPELQIPLFLVFLVLYLLTVAGNLGIITLTSVDPQLQTPMYFFLRHLAIINLCNSTVVAPKMLVNFLVTKKTISYYGCAAQLGGFLVFIVAEIFTLAAMAYDRYVAIWSPLLYAVVVSPKVCRLLVSLTYLQSLITALTVSSCVFSVSYCSSNIINHFYCDDVPLLALSCSDTYIPETAVFIFSGTNLLFSMIVVLISYFNIVITILRIRSSEGRQKAFSTCASHMIAVVVFYGTLLFMYLQPRSNHSLDTDKMASVFYTLVIPVLNPLIYSLRNKNVKDALKRFLDNPCRSLKLM
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 8J2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MON1_ASPTN
Sequence: MDLTDQSRPQTASGDDPDGRVENAPSSSTTTASVGTNDRTETANPEEQPPPLPPRPNTLSLLDEGGASSRSLRQTGPVNLQSKATTAVTIPDIASNDAGKENYNLRGLAGALRAKASLSHLASSRASEAGDSASVRSSVPHTEAGEMENVFGDLLAAESGVVQQDGTGLLQFPEFQADDVEDDFACEFEPVGEVEEGEDNEEMVLEKWKSKRKHYLILSAAGKPIWTRHGDGALISTYVGIIQTIISFFQDSDDHLRSFTAGDTKFVVVTKGPLYFVAISRIHESETQLKLQLEALYMQILSTLTLPSLTHLFSVRPSTDLKRPLQGSETLLSTLADSFTRGSPSTLLSALECLKIRKAHRHIINNTLLKSRVNSLLYGLVVAGGRLVSVVRPKKHSLHPGDLQLLFSMIFEAEAVKTGGGESWIPVCLPGFNSSGYLYMYVSFLDLREDSSNVADDSTTKEESVAIVLISTDKESFFELQEMRNNLVEQLQKNYSLQVIKEAIDRGRPATTDIVPGTVLHHFLYKSRANVQFTMSSYDPEFSSISRRRRSVSLSS
What is the function of this protein?
Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
What are the official names of this protein?
Vacuolar fusion protein mon1.
What is the protein family that this protein belongs to?
Belongs to the MON1/SAND family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: LGR5_XENTR
Sequence: MDTSKTSFFLFSVLCSLQLVGAARPGKQQRSCPTPCECEQEGMLVRVDCSDRALTSLPRNLSIFTSYLDLSMNNITNLPSNVMHNLHFLEELRLAGNDLTYIPKGAFAGLGSLKVLMLQNNLLRQVPSEALHNLRSLQSLRLDANHISYVPPSSFNGLFSLRHLWLDDNSLTEIPVRALESLSALQAMTLALNKIHHIPDYAFRNLSSLVVLHLHNNRIYSLGKKCFDGLHSLETLDLNYNNLDEFPAAIKTLKNLKELGFHSNNIKSIPEQAFIGNPSLITIHFYDNPIQHVGRSAFQHLPELRTLILNGASQITEFPDLTGTTSLESLTLTGAQLVYLPSAVCTQLPNLQVLDLSYNHIKDLPSFSGCQRLQKIDLRHNEVYEIRSTTFQQLVGLRSLDLAWNKIAVIHPNSFSSLPSLIKLDLSSNHLTSFPVTGLHGLTHLKLTGNSALQDLIPSEHFPKLRVMEMPYAYQCCAFAVCDNLKHSGQMNKDENSSADDFYRKDIGLLHLQDDRDFEDFLLDFEEDVKVLHSVQCTPSAGPFKPCDHLFGSWLTRTGVWLIVLLSFVCNALVIATVFRPLSYVPSIKLLIGLIAIMNTLMGLSSGVLATVDALTFGNFAQYGAWWESGVGCQITGFLSVFAAETSIFLLTVAALERGFSIKCTTKFETKSSFINVKLSIVFCFLLSIVIAVSPLLSGSTYGTSPLCFPLLFGDPSSMGFMVALVLLNSLCFLVMTIAYTKLYCSLEKGELENIWDCSMVKHIALLLFTNCILYCPVAFLSFSSLLNLTFISPEVNKSILLLIIPLPACLNPLLYILFNPHFKEDIGSLKNGDILWSRSRQTSLASVSSEDAEKQSCDSTQALVTFANSSISYDLPATSSSSSYQMTNNYKLSAVAFVPCH
What is the function of this protein?
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle.  Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.  In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal.  Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
What are the official names of this protein?
Leucine-rich repeat-containing G-protein coupled receptor 5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Rapidly and constitutively internalized to the trans-Golgi network at steady state.
Protein: AROC_DEIGD
Sequence: MRYLTAGESHGPQLTAIIEGLPSQLPLGTSDINPWLRKRQGGYGRGRRMVIETDEAQILSGVRAGRTTGAPVTLVIANKDHRNWTEIMSPEPGGEPRKKALTAARPGHADLTGGIKYRHKDLRDVLERASARETAARVAVGAVALKLLSELGVEGANYVASLGGIETRAPFSWDQLDAIEASDLRTPDADAAAQMRERIDQAKKDGDTLGGILEVRFRGLPVGLGSYVHWDRKLDGRIAQACLSVQAMKGVEIGRAFENAVQPGSRVHDAVYYREGTYVRDTNSAGGLEAGMTNGEELIVRVAMKPIATLMKPLPTVNVVTHEAADAARERSDTTAVPAAGVILQCVIGWVLAEAMLEKFGGDTLPELQERVQAARAYAQAY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TIM13_KLULA
Sequence: MALTSIFGGSSSSSGTPATSSPSDVKTQLKSQISQELAIANATELVNKVTENCFEKCLNAPYAASQDNCVDQCLAKYMRSWNAISKAYINRIQQASVNGEI
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM13.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RF2_SALPK
Sequence: MFEINPVNNRIQDLTERTNVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAIVDTLDQMTQGLDDVSGLLELAVEADDEETFNEAVAELNTLEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLLRMYLRWAEARGFKTEVIEESEGEVAGIKSATIKISGEYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDDIDIDINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDTKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_YERPE
Sequence: MIEADRLISAAVINDEESIDRAIRPKLLTEYVGQPHVREQMEIFIQAAKQRGDALDHVLIFGPPGLGKTTLANIIANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVADLEHIVSRSAKCLGLELTPEGAHQLARRSRGTPRITNRLLRRVRDFAEVRADGAINGEVAMKALDMLNVDAEGFDFMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFIQRTPRGRIATNHAYKHFGITREE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: NRDR_RHOBA
Sequence: MRCPFCHSDNDKVQDSRTAEAGYVVRRKRLCQTCQRRFTTLEQIDALNVRVVKSDETREPFDREKIKRGIERACSKRAVTSDEIEKTVQKIEEAIYAEFDMEIPTATIGEVVLRKLATLDEVAYIRFASVYRDFDDAKDFLQIVSNLQRDAETEGR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: FMP3_PSEAI
Sequence: MKAQKGFTLIELMIVVAIIGILAAIAIPQYQNYVARSEGASALATINPLKTTVEESLSRGIAGSKILIGTTASTADTTYVGIDEKANKLGTVAVTIKDTGDGTIKFNFATGQSSPKNAGREITLNRTAEGVWTCTSTQEEMFIPKGCNEP
What are the official names of this protein?
Fimbrial protein, Pilin.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: PSBF_SCHCH
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SUCO_MOUSE
Sequence: MKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTSYYSQDDNCAIGSEDTQFQKKNEREEPSNAELSGKSNSYLTISPEGNKIKDDYTVDVQDLETTKLSLPVVEALPTVDLHEESSSVVVGSETIENSSSSSTSERTPVSELDEVEKSGTLSIAKPGEVEQPEADCDAGEAPDADAPVEQPAFVSPPESLVGQHIENVSSSHGKEKVTKSEFESKVSVSEQDGGDPKSALNTSDTLKNESSDYTKPGETDPTSVTSPKDPEDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERNVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATTEPKMTESTRVSTPVPSPEYVIKEVHTHDREPSTSDPPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSSWFESETHILCSELTSICCISSFSEYIYKWCSVRIALYRQRSRTVSKGKDFVPPQPSLLLPVESVEVSVPQPPSGDVDSENMEREAETVDLDDLSSVHQGHLINHTVDTIELEPSYPQTLSQSLLLDVTPEMNSLSKVEGSESVKSEGGYIPSQLMTQESSVEFDDKTEKKTESFSSAEKLSVIYETSKVNEVMDNTVKEDILSTEVVTKFPETVVPPPMNTATVPEGESVETKPSIADTLKHTVTPVMDPSLPEVKEDEQSPEDALLRGLQRTATDFYAELQNSTDLGYGNGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQLVSNLSATVAELKREVSDRQSYLVMSLVLCVVLGLMLCMQRCRTTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKTEKIETIKPADPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQTQKTKTEKRALKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI
What is the function of this protein?
Required for bone modeling during late embryogenesis.  Regulates type I collagen synthesis in osteoblasts during their postnatal maturation.
What are the official names of this protein?
SUN domain-containing ossification factor, Membrane protein CH1, Protein osteopotentia, SUN-like protein 1.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: ACYP_METHJ
Sequence: MKRVSMIVSGQVQGVGFRYYVQDIAEDMRITGWVRNLPDGTVEIDAEGKTDVLETFIRTISNTRQGAIQVRNVHVQEKEVCGYSIFTIRRD
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: OCSTP_HUMAN
Sequence: MPGHPGAAEQLVKTGWRSWHLGFWKALAPLQAAWDAFSQPVPASCGQLLTQLLLCASLAAAAAGLVYHWLASLLLYPPGPSAMVATVCGLLVFLSLGLVPPVRCLFALSVPTLGMEQGRRLLLSYSTATLAIAVVPNVLANVGAAGQVLRCVTEGSLESLLNTTHQLHAASRALGPTGQAGSRGLTFEAQDNGSAFYLHMLRVTQQVLEDFSGLESLARAAALGTQRVVTGLFMLGLLVESAWYLHCYLTDLRFDNIYATQQLTQRLAQAQATHLLAPPPTWLLQAAQLRLSQEELLSCLLRLGLLALLLVATAVAVATDHVAFLLAQATVDWAQKLPTVPITLTVKYDVAYTVLGFIPFLFNQLAPESPFLSVHSSYQWELRLTSARCPLLPARRPRAAAPLAAGALQLLAGSTVLLEAYARRLRHAIAASFFTAQEARRVRHLHARLQRRHDRHQGQQLPLGDPSCVPTPRPACKPPAWIDYRLDALRTESSEGEGKELWSCRDLSCNLGPVPPPCVTLGKSLHLSEPRFLHLHNDSIFTIDVTYFPRRDVVRMEGNTGHDRPG
What is the function of this protein?
Probable cell surface receptor that plays a role in cellular fusion and cell differentiation.  Cooperates with DCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs).  Involved in osteoclast bone resorption.  Promotes osteoclast differentiation and may play a role in the multinucleated osteoclast maturation (By similarity).
What are the official names of this protein?
Osteoclast stimulatory transmembrane protein, OC-STAMP.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y079_NPVOP
Sequence: MSLYRSKVWCVYIVRRDDGQLYTGITSDLSRRLGEHARGVGARCLRGAKRLQLLYCSASAYDHKTAAQMEYHLKRKRGKYFKLRLIKAQPRFLHQYLSADKPLR
What are the official names of this protein?
UPF0213 protein ORF82.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: LYSM3_MOUSE
Sequence: MAGRNQNRTVSLPGIQASGHVLAFGNCTDNDMLEEDAEVYELRSRGKEKVRRSASRDRLDDIVILTKDIQEGDTLNAVALQYCCTVADIKRVNNLISDQDFFALRSIKIPVKRFSSLTETLHPLKGRHILHPPPVPYFQEQDIVPADGSLSSSESAGSFLKEVDRDIEQIVKCTDTKKENLNEVVSALTAQQVRFEPDNKSIHRKDPYYGADWGIGWWTAVVIMLIVGIITPVFYLLYYEILAKVDVSHHSTVGSSHLHPGLTPPTQHREMENEIGPTKGIPVGQQDDHKLYRQDPQAHDAQHKT
What is the function of this protein?
Essential for Golgi structural integrity.
What are the official names of this protein?
LysM and putative peptidoglycan-binding domain-containing protein 3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Golgi apparatus.
Protein: NUP93_MOUSE
Sequence: MDTEGFGELLQQAEQLAAETEGISELPHVERNLQEIQQAGERLRSRTLTRTSQETADVKASVLLGSRGLDISHISQRLESLSAATTFEPLEPVKDTDIQGFLKNEKDNALLSAIEESRKRTFGMAEEYHRESMLVEWEQVKQRILHTLLASGEDALDFTQESEPSYIGDVNPPGRSSLDSIEMAYARQIYIYNEKIVSGHLQPNLVDLCASVAELDDKSISDMWAMVKQMTDVVLTPATDALKSRSSVEVRMDFVKQALGYLEQSYKNYTLVTVFGNLHQAQLGGVPGTYQLVRSFLNIKLPAPSPGLQDGEVEGHPVWALIYYCMRCGDLLAASQVVSRAQHQLGEFKTWFQEYMNSKDRRLSPATENKLRLHYRRALRNNTDPYKRAVYCIIGRCDITDNQSEVADKTEDYLWLKLNQVCFDDDGTSSPQDRLTLSQFQKQLLEDYGESHFTVNQQPFLYFQVLFLTAQFEAAIAFLFRMERLRCHAVHVALVLFELKLLLKSSGQSAQLLSHEPGDPPCMRRLNFVRLLMLYTRKFESTDPREALQYFYFLRDEKDSQGENMFLRCVSELVIESREFDMILGKLENDGSRKPGVIDKFTSDTKPIINKVASVAENKGLFEEAAKLYDLAKNADKVLELMNKLLSPVVPQISAPQSNKERLKNMALSIAERYRAQGISANKFVDSTFYLLLDLITFFDEYHSGHIDRAFDIIDRLKLVPLNQESVEERVAAFRNFSDEIRHNLSEVLLATMNILFTQFKRLKGTSPSSATRPQRVIEDRDSQLRSQARALITFAGMIPYRTSGDTNARLVQMEVLMN
What is the function of this protein?
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.  May anchor nucleoporins, but not NUP153 and TPR, to the NPC (By similarity).  During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (By similarity) (PubMed:26878725).
What are the official names of this protein?
Nuclear pore complex protein Nup93, 93 kDa nucleoporin, CBP-interacting protein 4, Nucleoporin Nup93.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin interacting component (NIC) family.
What are the subcellular locations of this protein?
Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Nucleus envelope. Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore.
Protein: STXB_SHIDY
Sequence: MKKTLLIAASLSFFSASALATPDCVTGKVEYTKYNDDDTFTVKVGDKELFTNRWNLQSLLLSAQITGMTVTIKTNACHNGGGFSEVIFR
What is the function of this protein?
The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
What are the official names of this protein?
Shiga toxin subunit B.
What is the protein family that this protein belongs to?
Belongs to the StxB family.
Protein: NRDR_SINFN
Sequence: MRCPYCSSEDSQVKDSRPAEDGNAIRRRRICPDCGGRFTTFERVQLRELMIIKKTGRKVPFDRDKLLRSFEIALRKRPVDRDRIERAVSGIVRRLESSGETEIPSEEIGLQVLEALKSLDDVAFVRYASVYRDFSHAEDFEKVIAEISAKIARDPSE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PGK_XYLFT
Sequence: MSIVRMTDLALSGKRVLIRQDLNVPIDQGRITSEQRIIASLPTIRVALERGAAVMVTSHLGRPKEGVWSEEDSLAPVAKRLSQLLGIEVPLRRDWVDGVQVAPGQLVLLENCRMNVGEAENDEALARKYAALCDVFVMDAFGTAHRAQASTHGVICCAAIAAGGPLLMAELDALSRGLKHPVKPLLAIVGGSKVSTKLELLSNLVNNVEQLITGGGIANTFLAAAGYPIGKSLYEADLIETAREIITVAKARGAEIPLPTDVVVAKQFLPGVTATVKTVDAIVADDLILDIGPQTARHYAALIETAATVVWNGPVGVFEFDAFSKGTEVLARAVAASSAFSIAGGGDTLAAIDKYGVADQISYISTGGGAFLEFLEGKTLPAVAALQARSG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMPA3_DANRE
Sequence: MAPMGIRLSPLGIAVFCLLGVGVIYHLYAGVLSSRLAFFRQKRTVDLRELLALSIDAAVQGGREVKRIREDNTLEEKSKGKTKEGASEKYTLGDLNSHRKMYYLIKNTFPNIQVNSEEHANAEGEATVWTRMIPEDILAKVSGGKEIPAEKITVWIDPLDATQEYTENLLKYVTTMVCVAVDGEPVIGVIHKPFTGYTVWGFVGEGSNVAPRDSYNTNSPKVIVSRSHAGKVKSFVQTAFGNNTEIIPAGGAGYKALALLNPTDDKQETADIYIHVTYIKKWDICAGDAILKSLGGQMTTLKGEQIDYSGLEGNKGGLLASMKVDHKALVKRLPLWEDNKQ
What are the official names of this protein?
Inositol monophosphatase 3, IMP 3, IMPase 3, 3'(2'), 5'-bisphosphate nucleotidase 2, Inositol monophosphatase domain-containing protein 1, Inositol-1(or 4)-monophosphatase 3, Myo-inositol monophosphatase A3.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LPW_SHIFL
Sequence: MKAIFVLKGWWRTS
What is the function of this protein?
This protein is involved in control of the biosynthesis of tryptophan.
What are the official names of this protein?
trp operon leader peptide.
Protein: RCNR_ECOK1
Sequence: MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAAIRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK
What is the function of this protein?
Repressor of rcnA expression.  Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt.  In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity).
What are the official names of this protein?
Transcriptional repressor RcnR.
What is the protein family that this protein belongs to?
Belongs to the FrmR/RcnR family.
What are the subcellular locations of this protein?
Cytoplasm.