PharMolix/UniProtQA huggingface dataset:
Protein: CCD61_DANRE
Sequence: MEVGTVVQEEMKFRGSEFAVKVEMAERLLIVEISDVVTADQWRGEFGPAYIEDLTRKTGNFKQFPVFCSMLESAVHKSSDSVTLDLLTYSDLELLRNRKAGVVGRPRAQPQSPALSAKRYLILIYTVEFDRIHYPLPLPYLGKPDPAELQKEIRALRSELKTLGLRGDHKVSDQETRKLRTELALVRDEKEALAKALDRLQMVGSGSAPGARGLREAVHSLEEQLLKERAKSQRSAIKKSQEQRLLVEQLEELRASERALRIRVKSLTTELALLRRGRATPVLSDRGGLRGDGVVHRSLSRERSLTRVGIRARSGSRERIEDRGRRSEERVRRADSSGSRNCITRPSPSPTGSRVPRFDPTAYIQDRQRRQKEAELKSQRKIRRDMLASPSLMERGRSRSREPVPQLMRAGSAGRGRSVSVESRRSRCSSEGSVAEFEELAKPLNSRGRKLMSNGPAVSRGRHINKKPMCSTPAQRMRAGDTSMDTGADLSEIDARLQALQDYMRDLDTGH
What is the function of this protein?
Microtubule-binding centrosomal protein required for centriole cohesion, independently of the centrosome-associated protein/CEP250 and rootletin/CROCC linker.  In interphase, required for anchoring microtubule at the mother centriole subdistal appendages and for centrosome positioning.  During mitosis, may be involved in spindle assembly and chromatin alignment by regulating the organization of spindle microtubules into a symmetrical structure.  Plays a non-essential role in ciliogenesis.
What are the official names of this protein?
Centrosomal protein CCDC61, Coiled-coil domain-containing protein 61, VFL3 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC61 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=Localization at the centriolar satellite is dependent on intact microtubule network. Localizes at the centriole subdistal appendages and proximal ends. Localized to centrosomal/satellite-like structures with the onset of centrosome separation in early G2.
Protein: TRHO_CUPMC
Sequence: MQIVNISAYKFVTLEDIETLRPVMRERCDAAGLKGTILLAPEGINMFLAGTREQIDEFMAWLHADARFADIAPKESLSENQPFKRMLVRAKKEIITMKMPLIRPEAGRAPSVRPVDLKRWLDQGHDDDGRPVVMLDTRNAFEVAVGTFDKAVEYGIDKFSEFPPAVAENKAEFEGKTIVSFCTGGIRCEKAAIHMQEVGIDHVYQLEGGILKYFEEVGGSHYNGDCFVFDYRTALNPNLEPAGPVQCFACRAVVTPEEQQHPKYVVGKSCPHCVDTATQAAA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ZN575_MACFA
Sequence: MMLEVPRYTWRSPSNIKVVAEPGLGPGRWLLPGAHQPSCPPAPHQGPLQKPSQSAPGPTASASAPPRPRRRPPPQRPHRCPDCDKAFSYPSKLATHRLAHGGARPHPCPDCPKAFSYPSKLAAHRLTHSGARPHPCPHCPKAFGHRSKLAAHLWTHAPTRPYPCPDCPKSFCYPSKLAAHRHTHHATDARPYPCPHCPKAFSFPSKLAAHRLCHDPPTAPGSQATARHRCSSCGQAFGQRRLLLLHQRSHHQVEHKGERD
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 575.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HOA_KLEP7
Sequence: MNGKKLYISDVTLRDGMHAIRHQYSLAQVQQIAGALDKAGVDSIEVAHGDGLQGSSFNYGFGAHSDIAWIEAAAAAVSQAKIATLLLPGIGTLHDLKAAYQAGARVVRVATHCSEADVAAQHIAFARELGMDTVGFLMMSHMISPQALAQQALKMESYGATCIYVVDSGGAMNMNDIRDRFRALKAVLKPETATGMHAHHNLSLGVANSIVAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMNAADELVRPLQDRPVRVDRETLALGYAGVYSSFLRHSEAAAKRYGLSAVDILVELGKRRMVGGQEDMIVDVALDLLNRNK
What is the function of this protein?
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde.  Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: PLPHP_YEAST
Sequence: MSTGITYDEDRKTQLIAQYESVREVVNAEAKNVHVNENASKILLLVVSKLKPASDIQILYDHGVREFGENYVQELIEKAKLLPDDIKWHFIGGLQTNKCKDLAKVPNLYSVETIDSLKKAKKLNESRAKFQPDCNPILCNVQINTSHEDQKSGLNNEAEIFEVIDFFLSEECKYIKLNGLMTIGSWNVSHEDSKENRDFATLVEWKKKIDAKFGTSLKLSMGMSADFREAIRQGTAEVRIGTDIFGARPPKNEARII
What is the function of this protein?
Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.
What are the official names of this protein?
Pyridoxal phosphate homeostasis protein, PLP homeostasis protein.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PEX1_HUMAN
Sequence: MWGSDRLAGAGGGGAAVTVAFTNARDCFLHLPRRLVAQLHLLQNQAIEVVWSHQPAFLSWVEGRHFSDQGENVAEINRQVGQKLGLSNGGQVFLKPCSHVVSCQQVEVEPLSADDWEILELHAVSLEQHLLDQIRIVFPKAIFPVWVDQQTYIFIQIVALIPAASYGRLETDTKLLIQPKTRRAKENTFSKADAEYKKLHSYGRDQKGMMKELQTKQLQSNTVGITESNENESEIPVDSSSVASLWTMIGSIFSFQSEKKQETSWGLTEINAFKNMQSKVVPLDNIFRVCKSQPPSIYNASATSVFHKHCAIHVFPWDQEYFDVEPSFTVTYGKLVKLLSPKQQQSKTKQNVLSPEKEKQMSEPLDQKKIRSDHNEEDEKACVLQVVWNGLEELNNAIKYTKNVEVLHLGKVWIPDDLRKRLNIEMHAVVRITPVEVTPKIPRSLKLQPRENLPKDISEEDIKTVFYSWLQQSTTTMLPLVISEEEFIKLETKDGLKEFSLSIVHSWEKEKDKNIFLLSPNLLQKTTIQVLLDPMVKEENSEEIDFILPFLKLSSLGGVNSLGVSSLEHITHSLLGRPLSRQLMSLVAGLRNGALLLTGGKGSGKSTLAKAICKEAFDKLDAHVERVDCKALRGKRLENIQKTLEVAFSEAVWMQPSVVLLDDLDLIAGLPAVPEHEHSPDAVQSQRLAHALNDMIKEFISMGSLVALIATSQSQQSLHPLLVSAQGVHIFQCVQHIQPPNQEQRCEILCNVIKNKLDCDINKFTDLDLQHVAKETGGFVARDFTVLVDRAIHSRLSRQSISTREKLVLTTLDFQKALRGFLPASLRSVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVIARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEALHGMLLSSGLQDGSSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLDQSLVSLEMSEILPDESKFNMYRLYFGSSYESELGNGTSSDLSSQCLSAPSSMTQDLPGVPGKDQLFSQPPVLRTASQEGCQELTQEQRDQLRADISIIKGRYRSQSGEDESMNQPGPIKTRLAISQSHLMTALGHTRPSISEDDWKNFAELYESFQNPKRRKNQSGTMFRPGQKVTLA
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling (PubMed:11439091, PubMed:16314507, PubMed:16854980, PubMed:21362118, PubMed:29884772).  Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel (PubMed:29884772).  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5 (PubMed:29884772).
What are the official names of this protein?
Peroxisomal ATPase PEX1, Peroxin-1, Peroxisome biogenesis disorder protein 1, Peroxisome biogenesis factor 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane. Note=Associated with peroxisomal membranes.
Protein: IF3_CAMHC
Sequence: MSKGKEVFLNEDIRAAELRCIGDDGKAYGILPREKALEVAYQSGLDLVLIAPDAKPPVAKIMDYKKFCYQQEKKLKEAKKKQKVIEIKEIKFSAKIAQNDVNYKIKHAKEFLDDDKHVKLRVFLKGREIATPEIGVNLLNKIWDEYFEGNATKEKEPIIEGRYVSMLVTPKKV
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPTA1_MOUSE
Sequence: METPKETAVESSGPKVLETAEEIQHRRAEVLNQYQRFKDRVAERGQKLEESYHYQVFRRDADDLEKWIMEKLEIAKDKTYEPTNIQGKYQKHESFVSEVQAKSRVLPELEEIREARFAEDHFAHEATKTHLKQLRLLWDLLLELTQEKSDVLLRALKFYQYSQECEDILEWVKEKEAIVTLVELGDDWERTEVLHKKFEEFQEELTARKGKVDRVNQYANECAQEKHPKLPEIKAKQDEVNAAWDRLWSLALKRRESLSNAADLQRFKRDVNEAIQWMEEKEPQLTSEDYGKDLVSSEALFHNHKRLERNLAVMDDKVKELCAKADKLMISHSADAPQIQQMKLDLVSNWERIRALATNRYAKLKASYGYHRFLSDYDELSGWMKEKTALINADELPTDVASGEALLARHQQHKHEIDSYDDRFQSADATGQELLDGNHEASEEIREKMTILANDWAALLELWDKCQHQYRQCLDFHLFYRDSEQVDSWMSRQEAFLENEDLGNSVGSVEALLQKHDDFEEAFTAQEEKIITLDETATKLIDNDHYDSENIAAIRDGLLARRDALRERAATRRKLLVDSQLLQQLYQDSDDLKTWINKKKKLADDDDYKDVQNLKSRVQKQQDFEEELAVNEIMLNNLEKTGQEMIEDGHYASEAVAARLSEVANLWKELLEATAQKGTQLYEANQLLQFENNAEDLKRWLEEVEWQVTSEDYGKGLADVQNLLRKHGLLESDVTARQNQVDTLTDMAAHFEEIGHPDSGDIRARQESLLSRFEALKEPLAIRKKKLIDLLKLQQICRDSEDEEAWIQETEPSAASTHLGKDLVAAKNLLNRHEVILADIASHEPRIQVITERGNKMVEEGHFAAEDIASRVESLNKNMESLHARAIRRENDLKANVQLQQYLADLHEAEAWIKEKEPIVDNKNYGADEEAAGALLKKHEAFLVDLNAFENSIKALRDQAEVCQQQQAAPVDEAGREARVIALYDFEARSRREVSMKKNDVLTLLSSINKDWWKVEADDHQGFVPAVYVRKLAPDELPGFPQHRQEEPVNIPQLQQQVETLYHSLLDRAEERRRRLLQRYNEFLLAYEAGDMLEWIQEKKTENTGVELDDVWELQKKFDEFQRDLKSNEPRLKDINKVADELLFEELLTPEGAHIRQELNTRWNSLKRLADEQYQLLSSAHAVEMFHREADDVKEQIDKKCRALNAADPGSDLLSVQALQRQHEVFERDIIPLGEKVTTLGETAERLCESHPDATEDLQKQRTELNEAWDTLQGLTSDRKESLNEAHKFFLFLSKASDLENWIKTIGGVISSPELAEDLTGTEILLERHQEHHDDIKREDPTFQALEDFGTELIDSGHRNRREIDNTLQNINSKRDNLEKSWENRKKMLDQCLELQLFRGKCDQVESWMVARENSLRSDDRDHLNSLQALMKKRDDLDKAITAQEGKISDLENVATRLIDNDHYAKEEIAARLQRVLDRWKALKEQLLTELGKLGDYADLKQFYRDLEDLEEWINEMLPIACDESYKDPTNIQRKYLKHQAFENEVNGRAEQVDGVINLGNSLIERRVCDGDEENMQEQLDKLKENWDYLLERTTDKGQKLNEASRQQRFNTSIRDFEFWLSEAEGLLAMKDQARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNDLAQELISSGTFNIDQIEEKMNGVNERFENVQSLAAAHHEKLKETYALFQFFQDLDDEEAWIEEKLLRVSSQDYGRDLQSVQNLLKKHKRLEGELVAHEPAVQNVLDTAESLRDKAAVGKEEIQERLAQFVQHWEKLKELAKTRGVNLEESLEYLQFMENAEEEEAWLGEKCALVSRGDSGDTLAATQSLLKKHEALENDFAVHKNRVQDVCAQGEDILNKEETQNKDKISTKIQVLNEKTASLAKALAAWKSQLDDVHAFQQFNWKADVVESWIGEKEASLKTKSNGADLTAFLTLLAKHDTLDASLQSFQQERLSEIAELKDQLVAGEHSQAKAIEEQHAALLRHWEQLLEASRVHRQKLLEKQLPLQKAEELFMEFAHKASAFNNWCENAEEDLSEPVHCVSLNEIRQLQKEHEAFLASLAGAQEDFNYLLELDKQIKALNVPSSPYTWLTVDVLGRIWNHLPDIIKEREQELQKEEARQIKNFEMCQEFEQNASAFLQWIQETRAYFLDGSLLKETGTLESQLEANKRKQKEIQAMKRHLTKIEDLGDSMEEALILDIKYSTIGLAQQWDQLHQLGMRMQHNLEQQIQAKDTIGVSEETLKEFSTTYKHFDENLTGRLTHKEFRSCLRGLNYYLPMVEEGEPEPKFEKFLNAVDPGRKGYVSLEDYTSFLIDKESENIKTSDDIESAFQALAEGKAYITKEDMKQALTPEQVSFCTIHMQQYMDPRGRSQPAGYDYVGFTNSFFGN
What is the function of this protein?
Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane.  It associates with band 4. 1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.
What are the official names of this protein?
Spectrin alpha chain, erythrocytic 1, Erythroid alpha-spectrin.
What is the protein family that this protein belongs to?
Belongs to the spectrin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Protein: PP3_DMSVA
Sequence: MCRRTSVLPLVLSLFHLYYYGNVLSVSIPLSINITDRILPVQLNTTILMEGAEELNITQQLNVKHFQEGQLTREENFVCSHMTTTDLATDFFQLSKLAGAYDAAGSQDQRLHSPSLTSTLAPVVPETTPATLTPDGVTLNIRTSVTDINPLTRFTKAVRDLKEDITPGYDLTNGRKFGREFLRALEENGVRGRHKRDSTTDVLQMTLDVTESREKYVEIRDQCASVLGALIKSMVPSVSEHCLYHYHIKNIINCFTSHYIRLHNEPDFPLVMALYSEYLSLTVKIHYMDEILVSTLRA
What is the function of this protein?
Does not belong to rhabdoviridae replication core genes, and is specific to sigma virus: PP3 is presumably involved in host-virus interactions.
What are the official names of this protein?
Protein PP3.
What is the protein family that this protein belongs to?
Belongs to the sigma rhabdovirus PP3 family.
Protein: RR7_LATCL
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKALAYQIIYRAMKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLAASRKRPGRDMAFKLSSELVDAAKGSGDAIRKKEETHKMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid.
Protein: ZNF81_HUMAN
Sequence: MPANEDAPQPGEHGSACEVSVSFEDVTVDFSREEWQQLDSTQRRLYQDVMLENYSHLLSVGFEVPKPEVIFKLEQGEGPWTLEGEAPHQSCSDGKFGIKPSQRRISGKSTFHSEMEGEDTRDDSLYSILEELWQDAEQIKRCQEKHNKLLSRTTFLNKKILNTEWDYEYKDFGKFVHPSPNLILSQKRPHKRDSFGKSFKHNLDLHIHNKSNAAKNLDKTIGHGQVFTQNSSYSHHENTHTGVKFCERNQCGKVLSLKHSLSQNVKFPIGEKANTCTEFGKIFTQRSHFFAPQKIHTVEKPHELSKCVNVFTQKPLLSIYLRVHRDEKLYICTKCGKAFIQNSELIMHEKTHTREKPYKCNECGKSFFQVSSLLRHQTTHTGEKLFECSECGKGFSLNSALNIHQKIHTGERHHKCSECGKAFTQKSTLRMHQRIHTGERSYICTQCGQAFIQKAHLIAHQRIHTGEKPYECSDCGKSFPSKSQLQMHKRIHTGEKPYICTECGKAFTNRSNLNTHQKSHTGEKSYICAECGKAFTDRSNFNKHQTIHTGEKPYVCADCGRAFIQKSELITHQRIHTTEKPYKCPDCEKSFSKKPHLKVHQRIHTGEKPYICAECGKAFTDRSNFNKHQTIHTGDKPYKCSDCGKGFTQKSVLSMHRNIHT
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 81, HFZ20.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ECOT_SHIBS
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAEVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SUMO3_XENTR
Sequence: MSEEKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCDRQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVC
What is the function of this protein?
Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer.  Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process.  Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction.  Covalent attachment to its substrates requires prior activation by the E1 complex sae1-sae2 and linkage to the E2 enzyme ube2i (By similarity).
What are the official names of this protein?
Small ubiquitin-related modifier 3, SUMO-3.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family. SUMO subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, PML body.
Protein: TAM_SHIDS
Sequence: MSDWNPSLYLHFAAERSRPAVELLARVPLENVEYVADLGCGPGNSTALLHQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPEQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYSDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSRQAIIDWVTATGLRPWLQDLTESEQQLFLTRYHQMLEEQYPLQENGQILLAFPRLFIVARRTE
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNG_DROME
Sequence: MDMLNQILSINNGGAYGGGKAGGAFDPLTFAMKPQVVIRALCWLFSVVVFGCISSEGWTEKDGKEYCLYNGDGMACKYGNMVGVFGFLASMGFMGGEFLFERMSSVKSRKRYVMADMGFSALWTFMYFVAFLYLWSQWSSSAPPPLGIGAGSMKTAIWFCLFSIVSWALCALMAYKRFLIGAGDEFTSAFETDPANVVHQQAYGYSMDNDNDQYSASPFGQPQQGGMEQQQSGMEYQQPTY
What is the function of this protein?
Required for the correct formation of synaptic vesicles at nerve terminals and has a role in the regulation of the synaptic vesicle exo-endocytic cycle.
What are the official names of this protein?
Synaptogyrin.
What is the protein family that this protein belongs to?
Belongs to the synaptogyrin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=In larvae expressed in the synaptic neuropil of the central nervous system.
Protein: COG1_DICDI
Sequence: MAFNQMRSSGSTTDLNRLNSSSISGGGNINISNGGYGNQQLNAILSPIKSSSLSSMSNSSSYSNLNTLSSSKSFNSLTLIENQNDTTTTTSTNNGAISEQYQQLLSMIPKYQTKQYESDVKILFERNTPEQMKQMEFKKRSEIEDMKSQLRNLIGNKYRDLVEGSDAIVKMKKSTELISDNLSLMQSELKQFSEKRNHFRKGVSQDNLKLNKEKEIQKKISIFSKYCKFLIDIPEVIWRSLDSNDYFEVCVFFLKSKYLYSKITNENNLEIKRLLSKLTIIEKQWISMKQFPIKTIGYSKLFLNESTSRIIGTPIEKYIGSLSTLILFEKKSIKETFNEFLLSRRSVLFNSILSKDTNRPIQQTIEKMFQFLKMSIYYIMVLFYPRKYQTNNNNNNDQPEEEEQDDEKLISNDYQSKISKFKSNLQQYTSSLSSMSSTTTTTNSPTFESKMINKPVSEKELNQLPTLNFTSSILESTFNWRSPYLKECLKFYKDVSNGELSINSSGSQQGDDYQDINTNNNNSNNNNSGIDSQDIEYSLIEFDNFNSNFIFKRTSEWIEEIIEDFKLNLVQKFLIDIKSAKELSSLRSEIFDFILDFKNIVPFIQPPQTNSLSSSNSSINSIASPSVSLTSSTSSPIIATTKATVLTTPTPTPTPTPTTPISWNRMFSIICGKDMKYFLNIFEDIFLVKSESIIMDSFSRINLSKIQSDIFSQIKSEDKNFSEFLWFYNQDDPIQSIKNKTNGITPSNELFLTKINQLYNNIKSDFIYLLNDNNINNININNNNNNNNNNNNNNNNNRSMIITSQPKNLIKINEILIKEYMKKSFYKSLNEFTTSTQDRIDQLILLNKNKTTSGTTTSTNLKKDEILFISKLSKIFYKHIVNNPNLYFLNSLNIFDTTNISNCSTSFSKSNSINILDTISSPPQPPPSPTHSSPSIQRHTNNNNNNNNNNNNTSPIINNNNNNSEILKESLPIIDKLKQQFYYGCIVWVNEFVGDYSQILKQDLFNHDWNDSDRIKTWEKHIIQIESNGHNHNNDANDGGGDDDATVNGVNEHSTIIYIPYQTSPFITSYLMSISLEISKFSLNTIDKNILRFIIESITLNLFNIVNDLLSTSSTSTTASTSNLTSNNTTTTIKFNKEGYIQLLIDLKYIGFILFGRELNSSSSKKPTSQPTSNVIIKDSIFKKAKSHYQSIISTKNNVDENIELQKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEQLSNNIVYTFNQIIELVEKNLDPIDLAFYNSYIVKFIDQTYSKTLTLFGNFVYLHKSIVKPEKKQSINGGQQSPPLATTSSNGISGGKGIQQQQQQQSDLPNPMQLLKTNTKFQLFSIDTIQTITDAIATAPTTIPSSTSNSIQSSANNSAIASPISTIDYRNQQQQQQNNTNQQSLPSILSPTSASSTINTFSFMGKKISDLMYNTTKK
What is the function of this protein?
Required for normal Golgi function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 1, COG complex subunit 1, Component of oligomeric Golgi complex 1.
What is the protein family that this protein belongs to?
Belongs to the COG1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: LACTB_MOUSE
Sequence: MYRLLSSVTARAAATAGPAWDGGRRGAHRRPGLPVLGLGWAGGLGLGLGLALGAKLVVGLRGAVPIQSPADPEASGTTELSHEQALSPGSPHTPAPPAARGFSRAIESSRDLLHRIKDEVGAPGIVVGVSVDGKEVWSEGLGYADVENRVPCKPETVMRIASISKSLTMVALAKLWEAGKLDLDLPVQHYVPEFPEKEYEGEKVSVTTRLLISHLSGIRHYEKDIKKVKEEKAYKALKMVKGTPPPSDQEKELKEKGGKNNEKSDAPKAKVEQDSEARCRSAKPGKKKNDFEQGELYLKEKFENSIESLRLFKNDPLFFKPGSQFLYSTFGYTLLAAIVERASGYKYLDYMQKIFHDLDMLTTVQEENEPVIYNRARFYVYNKKKRLVNTPYVDNSYKWAGGGFLSTVGDLLKFGNAMLYGYQVGQFKNSNENLLPGYLKPETMVMMWTPVPNTEMSWDKEGKYAMAWGVVEKKQTYGSCRKQRHYASHTGGAVGASSVLLVLPEELDSEAVNNKVPPRGIIVSIICNMQSVGLNSTALKIALEFDKDRAD
What is the function of this protein?
Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (By similarity).  Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism (By similarity).  It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein (By similarity).  Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism (PubMed:28329758).
What are the official names of this protein?
Serine beta-lactamase-like protein LACTB, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BAT47_CAEEL
Sequence: MPPKLRNFDKSMEKYTDVVLVVKQERFYVSRAILSEHCTYFQSLFCGDSNYQEHIISDVEPQDFQKFLEVVHGEPAIFEATVQKILPLAQKFGSKTVLQKCERFLITISTVRLSTKWNLAKQYGLDELQAHCKLEFKTAQIVRKNPQPEPKSLAYSDKFIFDHSFEKVDGLAEGDMRRSQPITHLDFTWTIYITRKNQHLRVSLCCGKAHLTSDWTVRADFKMTLTAKGSPDLVSDTKGFFHLDSEKNFYWELGQEVEWDEIRDKCLADGKLEVETRVRIVKIRELPVEEFKPPRIVTVNAVKSYEGVLPPTKVLFGDFPFPKALAKEKPDYSDYIRVTPLTQQAKTSAPAETPDLQTPPRQQASAKPQASPAKSAGAPQLPQKVPLFPSGGAPSSPSAPEAPSEPPPPKIYPTLGANAPPAPPVQGKKFILKNVFGNVEAMKCHTAMACQKAVAYDFEWNLIISQKNNRLHVSLCCSKSNVTSEFRILADFELIIAGKNGGRPLKSKTNGCFNIEKTKNSSQELGQDVEWSTIVYDYMVDGRLTVEAHVNITRVTCLDAPKFKKLRNFDATGNSWDVMLIVAGQRFFVLKEILISNSARFKNIISKINFTAAPSTEIKLPDSSADHFQNFLEACYGDPSINDDTVHGILKIAQSYEAAGIVKRCEEYVIKYSKKTLEQKEKLAKHHNLKTLKAHCDYWKSRRKCC
What are the official names of this protein?
BTB and MATH domain-containing protein 47.
Protein: Y5530_DICDI
Sequence: MFIFFINTPTPPNIFFSKNIKIKKLMRFSCTEVCIFFSLIFFFFFFFFCVNWGCENNLLSRKYQMNRDTCNF
What are the official names of this protein?
Putative uncharacterized protein DDB_G0292940.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PHNX_SALTY
Sequence: MNRIHAVILDWAGTTVDFGSFAPTQIFVEAFRQAFDVEITLAEARVPMGLGKWQHIEALGKLPAVDARWQAKFGRSMSAADIDAIYAAFMPLQIAKVVDFSSPIAGVIDTIAALRAEGIKIGSCSGYPRAVMERLVPAAAGHGYRPDHWVATDDLAAGGRPGPWMALQNVIALGIDAVAHCVKVDDAAPGISEGLNAGMWTVGLAVSGNEFGATWDAYQTMSKEDVAVRREHAASKLYAAGAHYVVDSLADLPGVIAHINARLAQGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: MNMA_SALRD
Sequence: MSKKGRVLVAMSGGVDSSVTAVLLKERGYDVVGLTMKTWDYSTSGGRDGKEVGCCSIESMNDARVVATEHGFPHFVVDLREEFGDWVIERFTDEYLSGRTPNPCVLCNTHIKWDALLQRADDLDCEYIATGHYANVRYDDERDRYLLSRGLDRNKDQSYALWGLPQEHLARSIFPLGAYEKPEIREMAAEFGLDNVADKPDSYEICFIPDNDYPRFLKDRVDGLEEEVSGGTFVLSDGTVVGEHDGYPFYTIGQRRGLDLALGERVYVTDIDPETNTITVGPKEELMEQTLTAHEINLVKYPELDGERPAWGTIRYNDDGAGCLAWQPDEDTLKVAFAEPKRAITPGQSLVLYEDEDVLGGGWIHEVGGAENEAAERAAEAPA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB5_HUMAN
Sequence: MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).  Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.
What are the official names of this protein?
Proteasome subunit beta type-5, Macropain epsilon chain, Multicatalytic endopeptidase complex epsilon chain, Proteasome chain 6, Proteasome epsilon chain, Proteasome subunit MB1, Proteasome subunit X.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.