PharMolix/UniProtQA huggingface dataset:
Protein: KOJP_CALS4
Sequence: MQVIKKVEELMGDAKWLVFQEEYNNKLNGKYETLFTLTNGYMGIRGTFEEGSEGERPGSFIAGIFNRGEAQVRELVNVQNWMRLKIYIEGEEIRLDRCELLEFQRILDMKKGVLFRKTVVKDDKGRVTKIEGYRFVSRSNRHRSAIRFFITPLNYEGVIGVENLIEGTVLNSATHPKYRVKHLKVVKNESICKSGIYLETATTDENKRIAVGSTLRIYNLEDINRENIAFFRRFIPLGENSAEYLEFKGEREKTVVVDKFAVTYTSRDVEKDLLKNAVENDLFDFVSRGFDEELEKHIAEYDKLWSVADITIEGDEEADIALRFNIFHLMSSVNEKDPWVSIGAKGLHGEGYKGHVFWDTEIFMLPFFIYVYPEAARTLLMYRYNMLDAARRNAALNGYKGAQYPWESADTGMEETPKWGFDYKGNPVRIWTGDLEHHITADVAFAVWEYFRATNDIDFMLNFGAEIILETARFWASRCEYVEELDRYEINNVIGPDEFHEHVNNNAYTNYFAKWNIKKGLEIIGELKENYPDYYYAITHKISLTPEEVEKWKEVEKKIYIPYDKDKKLIEQFEGYFEKKDYVIEKFDENNMPVWPEGVDVTKLGDTQLIKQADVVMLMLLMPEEFDEETKRINYEYYEKRTMHKSSLSPSMYAIMGLKVGDHRNAYQSFIRSAKVDLADNQGNAVEGIHAASCGGTWQVAVFGFGGLEIDREGVLNINPWLPEKWEKLSYKIFWKGSLLEVTVAKEEVSVKKLKGRETVKIKVKGKEMAL
What is the function of this protein?
Hydrolyzes kojibiose in the presence of an inorganic phosphoric acid to form D-glucose and beta-D-glucose-1-phosphoric acid.
What are the official names of this protein?
Kojibiose phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 65 family.
Protein: RL28_CLOBM
Sequence: MSRKCEICGKGVVYGVQYSHSHRQSKRSFAPNIKRVKAIVNGTPKRVHVCTRCLRSGKVQRAI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RHXF2_HUMAN
Sequence: MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV
What is the function of this protein?
Transcription factor maybe involved in reproductive processes.  Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis.
What are the official names of this protein?
Rhox homeobox family member 2, Paired-like homeobox protein PEPP-2, Testis homeobox gene 1.
What is the protein family that this protein belongs to?
Belongs to the paired-like homeobox family. PEPP subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NSP4_ROTHK
Sequence: MDKLADLNYTLSVITLMNDTLHSIIQDPGMAYFTYIASVLTVLFTLHKASIPTMKIALKTSKCSYKVIKYCIVTIINTLLRLAGYKEQVTTKDEIEQQMDRIVKEMRRQLEMIDKLTTREIEQVELLKSIHDNLITRSVDVIDMSKEFNQKNIKTLDEWESGRNPYEPSEVTASM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: LODA_MARM1
Sequence: MALSVHPSIGVARLGNANTDNFVLNPMEIGGLPYEHDVDLKPTTTVVNFKDEAGCIRRQGQVFKVFGASNEELTLDSPNVKNIEWTVHLANKKAAWYEFRELNGNLLYGRDNSYSARGVPWRNASKTASSERQSLIIDLGPRSVSGVMATVEISINNIPETYLHPSYPSGELLQGSKHFESLGTLRTDSQGRLIVLGGYGFAGGNTDLSGYGGGDDWYDDISDGSVTCVVTYSDDSSETSTAWMVVGSPDFAPEIVNISTLSDTCFDVGVRNFDLVPDMYDSATGHYKSDYVANFDRDILPIIQRISQYQWVSNVQSMSGFFSFQFDYRDGSAANKANRMKYYNYFRQLDNKVIGDYDQPQQVLMSSEVEGDILPLMPMNSGSNSVSSSNFYDLTDNVVEKFLALDATQLFLLGQWAEGEFTAGPADDYPVSDMDTASIGNCVGLPMCPGIEMTWSLQNPVIYKDAYQIKHYQDKAYFDVNGLTPERDECEEETGCEPGDLTKRMACPWQADFFNCTIQTVNFSEPSVNKASQTETVTSRTHYEWGNLPAGVSVPDQSSVSATKNVDEKVPLPPAYYSYWWPPQSPWDVLTGELDTEGQLHSHLPAGQQINYARGINSYSQMVEHWSALAFIRDRNQNNDGFPFFTETERNHELFDFKEVLVGQVTGNSEDNETSLPVFFINANKESLEGKGTKKGKLMASYFEERAFSKVRSSNIRPRSGTRMRG
What is the function of this protein?
Has antibacterial activity against a wide spectrum of Gram-positive and Gram-negative bacteria including nosocomial isolates of S. aureus and Pseudomonas sp.  The antimicrobial activity is due to hydrogen peroxide generated by its lysine oxidase activity.  Also has autotoxic activity.  Involved in biofilm differentiation; responsible for cell death within microcolonies during biofilm development which is linked to the generation of a phenotypically diverse dispersal population and thus may play a role in colonization.
What are the official names of this protein?
L-lysine 6-oxidase, L-lysine-epsilon-oxidase, Marinocine.
What are the subcellular locations of this protein?
Secreted.
Protein: DADA_MAGSA
Sequence: MKVVVIGAGVVGTASAWYLAKAGHEVTVVDRREGAGLETSFANGGQISPCHAEPWANPSVLPKVLKWLGREDAPLLFRWNRWDPALWAWGLRFLANCSRSRAEINTERTLRVALYSRACLGELRAETGIAYDQQVRGILHVYRDGAEFEHACRAAEVMIRHGLRRLPRTPAECTAIEPALGAVQGELAGGIYTPDDESGDAHKFTRELAALAAAKGVEFRWNVPIQSLLADGDRVAGLATSDGTIRAESYVLAAGCDSPLLARPLGLRLPIIPAKGYSVTVPVDNHAGAPLVSITDDEHKMVYSRLGDRLRAAGTAEMAGYDRMPNPVRNRLILDNARRLFPDGGDFDRAEPWAGLRPVTPDSVPLLGATPLRNLWLNTGHGTLGWTMSCGSGRIVADLVSGRPSAISMDGLGIDRFTSYLW
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: ATG9_NEOFI
Sequence: MMTSNILSRFLPPNGSPSVYETIRHHDATSDSSDVEERAGLTLEDGSGEHYSDRELEDAMTDAERSRLLDPDDAFIRRKSPRKASVAGPSKSNSRHRHSGRPRWAHDASPGHDFEDGDDDVPASLLVEGHHDDDDDDLKSRLPPPPTSHFTPDNRQTSLPGPSTRGDRARWRAAREQQPLHHADRRRAPAVRWSLGQPNLNTVDPKEKAMWMWANVENLDNFLKDVYTYFLGNGIWSILLNRVLSLLTFAFVIGFTTFLTNCIDYHKVRGSKTLNDILIEQCTTKMSLSSTFLLWLLTLFWIGKAFQCLLDIRRLKHMHDFYYYLLGVSDTDIQTISWQEVVSRLMTLRDANPATAGAVSARHRKFMGSQSKQRMDAHDIANRLMRKENYLIALINKDILDLTLPIPFLRNKQLFSQTLEWNINLCIMDYVFNEQGQVRTLFLKDTHRKALSEGLRRRFIFAGIMNIFVAPFIVVYFMMHYFFRYFNEYKKNPSQIGSRQYTPLAEWKFREFNELWHLFERRINMSYPFASRYVDQFPKDKTVQVAGFVAFVSGALASVLALASIVDPELFLGFEITHDRTVLFYLGVFGSVWAVARGLVPEETTVFDPEYALLEVINYTHYAPSHWKGRLHSDEVRREFAELYQMKIVIFLEEILSMIFTPFILWFNLPKCSDRLIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVINQGDRREPARQDLRADYFSTKDGKMLASYYGFLDNYGANHRGSHPATRRQFHPPPAFPTLGSPPAGEMGTIGDRLDQTQTRHGLAGPFMGQQSVFGPSRYGPTGLGDHASPAPSILLDPHHQPSTSGFRGTSRAAAFPRYRSSRAHPPTSGTIADGDESPVATGGSDPSRPAANAAGASSAGGVGTSDSNLGDSWRMNLAEDVDDDNTEGGENVDAIAGGAGVLGLIQQLQRVNKDTRGRTAVGL
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through atg2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: THIM_HAEIG
Sequence: MQSIYLSKIREQNPLIHNITNIVAANFSANGLLALGASPLMSANIEEMQEVPKISQALVINIGTLIGKDREAMLQAGKTANEVGIPVVLDPVGVGATSYRRETISQLLAEVKFALIRGNAGELAAIAGEAWQAKGVDAGQGEVDLKAVAEKVAQRYGCTVLISGVVDIVSDGTQTATVHNGTSLFPKVTASGCLLSAVCAAFLAVSEGNYFSATLEACVAYTIAGECAAQGLTTQVGQFQIRLLDELAALSPETIGQRGRINE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: IGWS_GINCI
Sequence: PAVQGNDKKYTMSSVLKVSAADWKTNRFYQCQAGYNLNDMVESRFETPKIQEPNITALVPSVDFISSQNAVLGCVISGFAPDNIRVSWKKDQVDQTGVVLSSKRRTDNTFETISYLIIPTVNWKIGDKYTCEVSHPPSNFRSMISMKYQEGEKSSCPSGSPPGTCPPCSLTPELLYHTNLSVTLRNGEKHQYKCD
What are the official names of this protein?
Splenic IgW, short secretory form.
What are the subcellular locations of this protein?
Secreted.
Protein: IFGE_PENRF
Sequence: MASVKSRVFAITGGASGIGAATSRLLAERGATAVCVGDISCKNFDELKESMKKINPATEVHCSLLDVTSPTEVEKWVKSIVAKFGNLHGAANIAGIAQGAGLRNSPTILEEGDEEWSKVLKVNLDGVFYCTRAEVRAMKSLPSDDRSIVNVGSIAALSHIPDVYAYGTSKGASTYFTTCVAADTFPFGIRVNSVSPGITDTPLLPQFIPKAKTSDEVKEVYRKEGFSVVKAGDVARTIVWLLSEDSSPVYGANINVGASMP
What is the function of this protein?
Chanoclavine-I dehydrogenase; part of the gene cluster that mediates the biosynthesis of isofumigaclavines, fungal ergot alkaloids (PubMed:28620689, PubMed:28902217).  The tryptophan dimethylallyltransferase ifgA catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:28620689).  The second step is catalyzed by the methyltransferase ifgB that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of N-methyl-dimethylallyl-L-tryptophan (PubMed:28620689).  The catalase ifgD and the FAD-dependent oxidoreductase ifgC then transform N-methyl-dimethylallyl-L-tryptophan to chanoclavine-I which is further oxidized by ifgE in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:28902217).  The chanoclavine-I aldehyde reductases ifgG and/or fgaOx3 reduce chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline (PubMed:28620689, PubMed:28902217).  The festuclavine dehydrogenases ifgF1 and/or ifgF2 then catalyze the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine (PubMed:28620689).  Hydrolysis of festuclavine by a yet undetermined cytochrome P450 monooxygenase (called ifgH) then leads to the formation of isofumigaclavine B which is in turn acetylated by ifgI to isofumigaclavine A (PubMed:28620689).  Penicillium roqueforti has interestingly at least two sets of genes for the consumption of chanoclavine-I aldehyde on three different loci, the OYEs ifgG/fgaOx3 and the festuclavine synthase homologs ifgF1/ifgF2 (PubMed:28620689, PubMed:28902217).  The reason for the duplication of these genes is unclear, probably to ensure the conversion of chanoclavine-I aldehyde by differential gene expression under various environmental conditions (PubMed:28902217).
What are the official names of this protein?
Chanoclavine-I dehydrogenase ifgE, Isofumigaclavine biosynthesis cluster A protein E, Short-chain dehydrogenase/reductase ifgE.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MDV1_NEUCR
Sequence: MANSDQNRDVFPDDVSIDDDTSVISTRGLEAFGRKVTTTASHLIGPITDPTSHPHYQTAMTEIHKQLQKPTLQRGVFAIARTTPTDLVRSKLSSKEIQSRALAYVPDELLRNIPASSNSYSLFQGFQASFPDFTDDGKKHKRRVSRGRKMLDESPVQPGSPHAVQRLKKDKASMMHQLEMLGVRKNMASSEIREIDNKIANLHGMRKIILDRLANLEKEEAVLEHDIMDVESRLDEAQELADEAESLAMATPNKSEEDLSRTEEGFMSQSIYEKLPAANTPPGKKKPRNHRKKTLPILHEHFEPGTMIRSMRAHQDNITALDFDAPFGLMVSAAMDDSVRVWDLNAGRCIGTLEGHTASVRTLQIEDNFLATGSMDATIKLWDLSKAHYDPQGSQEVDEEDEDLAFVNPNDHAVDPPAGSMADCPLFTLEAHLDEITALHFRGDVLVSGSADKTLRQWDLTKGRCVQTLDVMWAAAQATAMGSSDGPWRQTSRSADGSADFVGALQVFESALACGTADGMVRLWDLRSGQVHRSLVGHTGPVTCLQFDDVHLVTGSLDRSIRIWDLRTGSIFDAYAYDHPITSMMFDTRRIVCAAGEDVVKVYDKVEGRHWDCGAGITEAEKAKSPAIVERVRIRDGYMVEGRQDGVVGVWTC
What is the function of this protein?
Involved in mitochondrial fission.  Acts as an adapter protein required to form mitochondrial fission complexes.  Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity).
What are the official names of this protein?
Mitochondrial division protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MDV1/CAF4 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YIDD_XANOM
Sequence: MQVAYHWQVISRLLIALLRFYKLFISPLLGPRCRFAPSCSEYAMTAIGRFGPLRGSWLAARRLGRCHPFHPGGFDPVPDAPASPSSSCSCKGPHP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DHX30_CHICK
Sequence: MAALGLLLQAAAACGSAGPLRLGRCYRGARGLCTRLAEPDGLEGARQEDEEEQPPPPGAEEQSTAMVKDSRDLLKEFPQPKNLLNSVIGRALGISHARDKLVYIHTNGPRKKKVTLHIKWPKNVEVEGYGTKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRLLADQLGCPDERWCSEGKWRSKSGPSLADLSTCWRRMEPDDPIQPMEQGRMPKAMRREELEEGELEEGELEEGELEEEAIDVSDYLPMAHQDARTPGRDASRGGSSIEMTDDNTAIRALTQFPLPKNLLAQVIQIATSSSTVKEYMQFRTVGTKTKICKLTLRWPCPMTFAAKGRRKVEAENKAAALACQKLKSLGLVDKNNNPLSHAMYNMTSLRELGENQRKPCHIKVPEATLRKIENYLNHYPVDIRESRPRIADDMMNLSKESGAISDAITGKTYIPMLEAEEVRLSQNLLALWKRRGSSWQESHPLPVDPHKDTILSAIEQNPVVVIAGDTGCGKTTRIPQLLLEHYILEGRGARCNVVITQPRRISAISVAQRVAQELGPNMRKNVGYQVRLESKPPARGGALLFCTVGILLRKLQGNPSLEGVSHVVVDEVHERDVNTDFLLILLKGIQKLNPDLRLVLMSATGDNQRFSHYFGGCPVVKVPGFMYPVKEYYLEEILAKLGRHRHRHYEIKQSDDECVLDLDLITDLVLQIDAHGEPGGILCFLPGWQEIKGVQQRLLEMLGSQNSRYLVLPVHSNIPMMDQQNIFQRPPPGVRKIVLATNIAETSITINDIVHVVDSGTHKEERYDLKTKVSCLETVWVSKSNVVQRRGRAGRCQSGFAYHLFPRSRLDKMPTYQVPEILRTPLENLVVQAKIHMPEKTAVEFLSKALDSPDIKAVDEAVILLQEIGVLDQREALTTLGKRLAQISTDPRLAKAIVLASIYRCLHPLLVIVSCLTRDPFSSSLQNRAEVDKAKAVLSRESGSDHLAFVRAVAGWEEVLRRRDSRARDNYLQDYYLYGPSLRFINGLVKQFSENLYEAFLVSSPSDCTMPSSVCNQYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSYAYRTKAGTVLLHKSTINREASKLYSRWLTYFMAVKSNGGVFVRDSSQVHPLAVLLMTDTDIHVRDDGWRATVSLTDSDLLVLEGDSYTIRLLRDFRVSLSKMVETCLCYEMAAIPGDLHHQHSQLLDILVDLLKGPPGSFGA
What is the function of this protein?
RNA-dependent helicase.  Plays an important role in the assembly of the mitochondrial large ribosomal subunit.  Required for optimal function of the zinc-finger antiviral protein ZC3HAV1.  Associates with mitochondrial DNA.  Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD.
What are the official names of this protein?
ATP-dependent RNA helicase DHX30, DEAH box protein 30.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. Relocalizes to stress granules upon heat stress.
Protein: GLB2_NIPBR
Sequence: MADVKKNCLASLSLAPISKAQQAQVGKDFYKFFFTNHPDLRKYFKGAENFTADDVQKSDRFEKLGSGLLLSVHILANTFDNEDVFRAFCRETIDRHVGRGLDPALWKAFWSVWVAFLESKGGVSGDQKAAWDKLGTVFNDECQHQLAKHGLPHL
What are the official names of this protein?
Myoglobin, Globin, body wall isoform.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_CHLL3
Sequence: MTRIKICGITRMEDARAAALFGADALGFNFSPESPRCVTKDAARTMVCALPPFIEGVGVFVEQDPREIIEICRYCGLSVAQLHGSRYSEEETKLVLEGVRVLKVFRPETDFTPAAVLRFREATGVSAFLFDTYRPGMEGGTGEQMEGSLAERIFSGLPEGCYGVLAGGLNPGNVREAVQSLRPYALDTASGVEESPGIKSHEKMQAFVQAVRAAGER
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: T2FB_DROME
Sequence: MSKEDKEKTQIIDKDLDLSNAGRGVWLVKVPKYIAQKWEKAPTNMDVGKLRINKTPGQKAQVSLSLTPAVLALDPEEKIPTEHILDVSQVTKQTLGVFSHMAPSDGKENSTTSAAQPDNEKLYMEGRIVQKLECRPIADNCYMKLKLESIRKASEPQRRVQPIDKIVQNFKPVKDHAHNIEYRERKKAEGKKARDDKNAVMDMLFHAFEKHQYYNIKDLVKITNQPISYLKEILKDVCDYNMKNPHKNMWELKKEYRHYKTEEKKEEEHKSGSSDSE
What is the function of this protein?
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.
What are the official names of this protein?
General transcription factor IIF subunit 2, Transcription initiation factor IIF subunit beta, TFIIF-beta.
What is the protein family that this protein belongs to?
Belongs to the TFIIF beta subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CARA_BRUO2
Sequence: MTETTPKTAPWTVQKRTAVLVLADGTVIEGKGLGATGAVEAEVVFNTALTGYEEILTDPSYAGQIVTFTFPHIGNVGANAEDIEDLTPANRHGAVGAIFKADITAPSNFRAAKDLDSWLKHRGIIALAGIDTRALTALIRERGAQNAVIAHDPNGNFDLDALKARAANWCGLENLDLAKDVTIGQSLVWKELPWTLQDGYGEQDAPQYHVVALDFGVKRNILRLLTGLGAKVTVLPATATAEDVLAHNPDGVFLSNGPGDPAATGEYAVPTIGKLVETGIPLFGICLGHQMLALALGGRTEKMHQGHHGANHPVKDYTTGKVEIVSMNHGFAVDSDSLPENVEETHVSLFDGTNCGLRVVGKPVFSVQHHPEASPGPQDSHYLFRRFINLIRERKGQAPLPEREQAA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: NO36B_SOYBN
Sequence: EERVLTPHTPSLKTVCFGLALASLINKGCVLTFFLEWRKQIHILRRRRGLATAWQTGKSQKRQWTPLGSLWLCIAHVVLLAVECNNKQSWSSF
What are the official names of this protein?
Early nodulin-36B, N-36B.
Protein: ASTE_SALHS
Sequence: MDNFLALTLSGTTPRVTQGKGAGFRWRWLGHGLLELTPDAPVDRALILSAGIHGNETAPVEMLDRLLSALFSGSLTLTWRVLVVLGNPQALTAGIRYGHSDMNRMFGGRWQSFAESDETRRARELELSLETFFSSGQARVRWHLDLHTAIRGSHHLRFGVLPQRDRPWETDFLAWLGAAGLEALVFHQAPGGTFTHFSSEHFGALSCTLELGKALPFGQNDLTQFNVTSQALSALLSGVETSTSFSPPLRYRVVSQITRHSDKFALYMDAQTLNFTAFAKGTLLAEEGDKRVTVTHDVEYVLFPNPSVACGLRAGLMLERLP
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: VKTK1_DABRR
Sequence: MSSGGLLLLLGLLTLWAELTPISGQDRPKFCNLAPESGRCRGHLRRIYYNPDSNKCEVFFYGGCGGNDNNFETRKKCRQTCGAPRKGRPT
What is the function of this protein?
Serine protease inhibitor.  Inhibits activated protein C (APC) with an IC(50) of 3. 5 nM in the presence of heparin (to which it strongly binds) and an IC(50) of 88. 9 nM in its absence.  Other targets are also significantly inhibited in presence of heparin: trypsin (PRSS1) (45%), coagulation FXIa (F11) (40%), and plasmin (PLG) (70%).  In vivo, synergizes with RVV-X in promoting coagulation in mice and by extension in Russell's viper bite patients.
What are the official names of this protein?
Kunitz-type serine protease inhibitor DrKIn-I, Daboia russelii Kunitz Inhibitor-I.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: LR10B_HUMAN
Sequence: MGIAESTPDELPSDAEEQLRSGDQQLELSGRRLRRLPSAVCALSRLQKLYVSGTGLRELPEEIEELRELRILALDFNKLERLPDGLCRLPRLTRLYLGGNRLLALPADFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRFEEFPPALLRMGRLHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTGPPRVADTVFLVGEGAVERMAERDEPTPRPPPRRPARAFEDEEEEDLLIGGAGSRALGAPGGSFRALEAAPGLGT
What are the official names of this protein?
Leucine-rich repeat-containing protein 10B.
Protein: BHMT1_XENTR
Sequence: MAPTGAKKGLLERLDAGEVVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGANVMQTFTFYASDDKLENRGNYVAKKISGQKVNEAACDIAREVANEGDALVAGGVSQTPSYLSCKSEVEVKGIFRKQLDVFIKKNVDFLIAEYFEHVEEAVWAVEVLKESGKPVAATLCIGPQGDLNGVTPGECAVRLAKAGASVVGVNCHFDPMTCIATVKLMKEGLVAAKVKAHLMTQPLAYHTPDCGKQGFIDLPEFPFALEPRIVTRWDIHKYAREAYNLGVRYIGGCCGFEPYHTRAIAEELAPERGFLPPGSEKHGSWGSGLEMHTKPWVRARARRDYWEKLPPASGRPCCPSMSKPDAWGVTKGDADLMQQKEATTEQQLIDLFAKQCIKSN
What is the function of this protein?
Involved in the regulation of homocysteine metabolism.  Converts betaine and homocysteine to dimethylglycine and methionine, respectively.  This reaction is also required for the irreversible oxidation of choline (By similarity).
What are the official names of this protein?
Betaine--homocysteine S-methyltransferase 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_BRUC2
Sequence: MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRPDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRKPLKAALLDQRLIAGLGNIYVCEALWRAGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: CYAY_ECO5E
Sequence: MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFRDLLEQAATQQAGETVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: OPGH_SHEB2
Sequence: MTVSENSVLETEVLVGGSAMPNERPGAMEPQNLSKMPEGFPRRSTVANGVRSRASRRFLVVGGALLLSLFAIYEMGAVFSIGGITPLEYLVLALFAVNFCWIALAFCSGIAGFLILLRKPRAKDLQVTELHTRTAILMPTYNESPDRVFSAVSVMAETLSQTGHGHAFDWFILSDTTDPDIALLEEQAFLVLRQETHKHSRVYYRRRRKNVARKAGNVADFCRRWGSRYDHLLVLDADSLMESSTITGLAQRMQADPDAGLIQTIPSLINGTTLMARLQQFAARIYGPVIGTGLGWWVQKEGNFWGHNAIIRTEAFMTAAGLPNLKGKPPFGGHIMSHDFVEAALIRRAGWSVVIAYDLPGSYEECPPSIIDLAVRDRRWCQGNLQHSRILPTKGLHWVSRLHLLTGIMAYLSSPFWLMLILTGLMLALQAHFIRPEYFTDQFSLFPTWPIMDSDRALRLFYITMGVLFGPKIFGVLLLLKDGEFARSVGGRIKAIFSVIFEVILSALIAPIMMFIHCGAVMSILMGRDSGWSPQRRDDGSMPWMTLIYRHRWHMLAGVMLGYAAILDSLTLLAWMSPALIGLWIAVPISAWTGSVKIGEVFKRAGILATPEERNPAQICLQAQDARAAYQKHIAEPWTLAQVLKDPALMELHLAMVDKQPLRAAGTPIEAMEAIVHVKVHEARCQQSALAVLNRQEMAMVLANPLMLRSLQKLPEQFVEEDLVSFC
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.