PharMolix/UniProtQA huggingface dataset:
Protein: MOMPF_CHLTH
Sequence: MKKLLKSVLVFAALSSASSLQALPVGNPAEPSLMIDGILWEGFGGDPCDPCTTWCDAISMRMGYYGDFVFDRVLKTDVNKEFEMGEALAGASGNTTSTLSKLVERTNPAYGKHMQDAEMFTNAACMTLNIWDRFDVFCTLGATSGYLKGNSASFNLVGLFGDGVNATKPAADSIPNVQLNQSVVELYTDTTFAWSVGARAALWECGCATLGASFQYAQSKPKIEELNVLCNAAEFTINKPKGYVGKEFPLDLTAGTDAATGTKDASIDYHEWQASLSLSYRLNMFTPYIGVKWSRASFDSDTIRIAQPRLVTPVVDITTLNPTIAGCGSVAGANTEGQISDTMQIVSLQLNKMKSRKSCGIAVGTTIVDADKYAVTVETRLIDERAAHVNAQFRF
What is the function of this protein?
Permits diffusion of specific solutes through the outer membrane.
What are the official names of this protein?
Major outer membrane porin, serovar F, MOMP.
What is the protein family that this protein belongs to?
Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: MDH_CAUVN
Sequence: MARAKIALIGAGMIGGTLAHIAAREELGDVILFDIAEGTPQGKALDIAEASAVFGKDVALKGANDYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKAVGEGIKAHAPNAFVICITNPLDAMVWALQQFSGLPKEKVIGMAGVLDSARFAYFLAEATGVSVEDIHAWTLGGHGDDMVPMVRHSTVGGLPLPELVKQGWLSQDKLDAIVERTRKGGGEIVALLKTGSAFYAPAESAIAMATSYLKDKKRVLPCATYLTGQYGLNDLYVGVPVVIGAGGAEKIVEFETNDDEKAMFAKSVESVKGLMEACKAIDSSLV
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: MURD_CLOBL
Sequence: MKSNFSKFKDFIKYKKVAVVGIGVSNRPLIKFLVKLGAKVTAFDKKHREKLGSISLELEEIGVDLVLGENYLDKLDGYDVIFKTPSMRIDRPEFVKAKESGAYITSEMEEFIKYCPAKVFGITGSDGKTTTTTLVYEMLKKEGYRTWVGGNIGTPLFANIEEMKEDHMVVLELSSFQLMTMDVSPEISLITNLSPNHLDVHKDFEEYVWAKKNIFKYQSSNNLLVLNKDDDLTNEMENEALGDVLKFSLVEKVYNGACLSNNKLTIQGKEVCDSKDINLKGRHNIANLLAAFCMVNKYVSIDSMKYVATNFSGVEHRCEFIREVNGVKYYNDSIASSPSRTLAGLNSFEKPVILIAGGYDKKIPFEPLAEGGYDKIKILILMGDTKNKIKSAFEKVISHKKCEMEIVIVNSMEEAVKVADNIAEKGDIITLSPACASFDMYPNFEIRGNEFKNIVNRL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_GEOKA
Sequence: MIDKVRAFIHRHQLLSEGAAVIVGVSGGPDSLALLHVFLSLRDEWKLQVIAAHVDHMFRGRESEEEMEFVKRFCVERRILCETAQIDVPAFQRSAGLGAQEAARICRYRFFAELMEKHQAGYVAVGHHGDDQVETILMRLVRGSTSKGYAGIPVKRPFHGGYLIRPFLAVSRAEIEAYCRQMGLSPRCDPSNEKDDYTRNRFRHHIVPLLRQENPRLHERFQQYSEMMAEDEQFLEELAADALNKVMEKQHRDAALSIGPFLELPRPLQRRVLQLLLLRLYGGVPPTLTSVHIGHILMLCERGRPSGMIDLPKGLKVIRSYDRCLFTFDAESGEKGYWFELPVPALLPLPNGYAIISEFGEHYPRKQAGNDWFVVDPASVSLPLRVRTRRRGDRMVLKGTGGTKKLKEIFIEAKIPRMERDRWPIVEDADGRILWVPGLKKSAFEAQNRGQARYILLQYQAMNS
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VC17_SWPVK
Sequence: MGSCVSVKSISISMDTVSISSIDDEYYYNIKNKPIYVRRKNSCSSTLESRYSTYSLESRYSTYSIKSVYF
What are the official names of this protein?
Uncharacterized protein C17.
Protein: HEAT1_DROME
Sequence: MSTALAQQLQKLAAPQSSVTLADARSRASILFDPKEAATKDRRSIYEIGLTGLQELTDFNPAFKEFQLTLFDEATLTLERSVELPEINKMLDAAIAKFLRLLSPYLLLRPAHMAFEWLLRRFQVHEYNRSEVMALILPYHETMIFVQIVKTMRLRSSDGDWYWLRPLQRPGVPLAKTAIINRAASNPAFLGFICQSTQKAVKELGPRAHQLQAQINFYATVVVGALQTAKPLQDWHITTILESLLRGLISDNIDFMAAAYVIVAQLVSRTKLKSKVCNALLERVANCPFERLHSESLLLLVCIYGKQQAALPHFKPETILNLVGKKWLISTLSSLAKGNIAIQSICMPLMTGAVAAIRDDDASSNSCKLFLDNLLSEVPMPKPTAQQLINCFLDTYVETAIDAPEPMETNSNEDDDTIVIDSDDEIETEKTTFQAWYSTYLEKLERRYPEAFDLSVKEALRSKSSTSNRQKALKLALGFRLNTTDEKAKHAYEKLYHYSADWRLSAVQKLLQNLNVTKKRERSVKLLQECLPDRINDDSGAVVSTLLSLPTEELAEMLGPLPLAQTLCHLLYRAQSEKDEEWQPVVPLAVRHLTSALVSGSYDTNLVLLALMPLLFPGEALAEHQHKALRILLGSDFVSKVPFLAELKVSNKFSDFNVGEHRQHFLDIIASSNQELSSQERALLQSVEDHGGELYIQKASQLTHLLLLLTAYAKRELQPRESLHMLEKIGLYSRRLQFRVVNGSQNTQNCAPLQLYVDFLLTLVKNTKWTALASTPWNQMTDELRLCLRLLEIICAQVFSEKADQPERQEWTRALQQSLQLILPEAQDRLEVLSNFYVFERLPELWPRDSDYAVFRLQGFIILEAVLSNPKSQIDCGLVHVLRVANACGSPLQTLRVQAINILQLISNRKLVSHVEQLVRSLLQRKSELSMDHEQYALILYTILEPEKATAKERLVLSKLKRSVLALASDPKQSPICTASLLAALKHVNDENFLNELLPLGLDSLKTITAGEDNQNIKQLPWPHSEIYKSVIERFEGRVALNVLLRKDLAWKLFEDSFAQYDTYVQLEQKLQPLPCVLLNSLTPETFEQMHAKHKIALIKLIVESATNSDNDSIFLASHRLLKRCRLDCQPLVPILLEMANTKVEKKQPVKRRSVQATQLDLTSPYWKQGMTLLELLEHKKQLVGAELLIPPLFELLQACLTMEEHSAAEYPKQLILSSLLHCCQTAQSAGVQLVKAMPESSFRIELVVQSLRNTRNPQTQQHALLFLTHCAGMYPQQVLHKIVEIFTFVGSTVARHDDAFSLHIIHNVVESIIPILLLNTGHNELVIPVLKVFADICTDVPVHRRLPLYATLFRVLEPKEHLWQFLCIIFESQVLLEQVPQKVSTDKSRLDFARELTLMFEDPTVAIQTCIRLLDYLAKLPATKSSLSGGSGSSVLSTEQQLFDVRTRTFKQLRHYKYLIMDFLSGISSCNEWEKKMKRPDPNELLPYYQEFILKTLAYVGVLNGALEAASETPSLEKFWRVLANHAHDVLDNAIGLLAPQHFISVITELLKHDHVYVRIKVMDLLVTKLSPSSDYFQQSNAEHFGVLFAPLQEIINGILEGSSNSAQQAKLQQTALHALQLLALRHGRDYIEECRSLLATLTKITKRRANVPKAVVGNVVLTLVEICASLKAHALAQLPKFAPQLTELLKEQVHQMASLKQGPDYVCSTLVTALHKLFKALPLFLGPYLVDIIGGLARLSVQLENPQLLQDKRTQVLKQKLADVWSAVAQGVEVRILVPSCAKAFSSLLEQQAYDELGHLMQQLLLQSVRHNSAAQLQPVQDPLSELFLQALNFRLQVRGLGLQRQLVSDVEASITETFVTWILKLSETSFRPMYSRVHKWALESTSRETRLTYFLLTNRIAEALKSLFVLFASDFVEDSSRLLTEHNSIRPEFEVEEREDDVDLLMAILNTLHHVFLYCSEDFINDHRFNVLMPPLVNQLENDLVLGNESLQQVLSNCIAQFAVATNDVMWKQLNSQVLLKTRTSNPEVRILAFNSCVAIARKLGESYAALLPETVPFIAELLEDEHQRVEKNTRTGVQELETILGESVQKYL
What is the function of this protein?
Ribosome biogenesis factor.  Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
HEAT repeat-containing protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HEATR1/UTP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MTHFS_MYCPN
Sequence: MDKNALRKQILQKRMALSTIEKSHLDQKINQKLVAFLTPKPCIKTIALYEPIKNEVTFVDFFFEFLKINQIRAVYPKVISDTEIIFIDQETNTFEPNQIDCFLIPLVGFNKDNYRLGFGKGYYDRYLMQLTRQQPKIGIAYSFQKGDFLADPWDVQLDLIINDE
What is the function of this protein?
Involved in folate metabolism.  Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.
What are the official names of this protein?
5-formyltetrahydrofolate cyclo-ligase, 5,10-methenyl-tetrahydrofolate synthetase, MTHFS, Methenyl-THF synthetase.
What is the protein family that this protein belongs to?
Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_GEOUR
Sequence: MAEITKADVITFIEKMSVLDLAEMVKELEEKFGVSAAAPVAVAAVAGPAVAEAAEEQTEFDVILKAAGANKIAVIKVVRALTSLGLKEAKDLVDGAPQPVKSGVSKEEAEEAKKQLAESGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PYRH_STRCO
Sequence: MSSTKAEKSDDGKVSGRFMLKLSGEAFSGGGGLGVDPDVVHAIAREIAAVVRDGAQIAIVIGGGNFFRGAELQVRGMDRARSDYMGMLGTVMNCLALQDFLEKEGVDCRVQTAITMGQVAEPYIPLRAVRHLEKGRVVIFGAGMGMPYFSTDTTAAQRALEIDAEALLMGKNGVDGVYDSDPKTNPDAVKFDALGYGEVITRDLKVADATAVTLCRDNSLPIVVFELLKEGNIARAVKGEKIGTLVGDQGSRD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_FRAT1
Sequence: MARLKDYYQKELVAKLKTELGLDNIMEVPTIKKITLNMGVGDAAKDKKIMTFALNDLTAIAGQKPVVTKSKKSIAGFKIRDGWPIGAKVTLRGDRMYEFLDRLITIAIPRIRDFRGLSAKSFDGRGNYSLGMREQISFPEIDYDKVDSIRGLDISITTTAKNDDQGRALLKAFGFPFKS
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NOD2_HYLLA
Sequence: MGEEGGSVSHDEEERASVLLGQYLGCEMCSQEAFQAQRSQLVELLVSGSLEGFESVLDWLLSWEVLSWEDYEGFHLLGQPLSHLARRLLDTVWNKGTWACQKLIAAAQEAQADSQSPKLHGCWDPHSLHPARDLQSHRPAIVRRLHSHVEGVLDLAWERGFVSQYECDEIRLPIFTPSQRARRLLDLATVKANGLAAFLLQHVQELPVPLALPLEAATCRKYMAKLRTTVSAQSRFLSTYDGAETLCLEDIYTENVLEVWADVGTAGPPPKSPATLGLEELFSTPGHLNDDADTVLVVGEAGSGKSTLLQRLHLLWAAGRDFQEFLFVFPFSCRQLQCMAKPLSVRTLLFEHCCWPDVGQEDIFQLLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTSVQTLLFNLLQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHREPGVADRLIRLLQATSALHGLCHLPVFSWMVSKCHQELLLQEGGSPKTTTDMYLLILQHFLLHAIPPDSASQGLGPSLLRGRLPTLLHLGRLALWGLGMCCYVFSAQQLQAAQVSPDDISLGFLVRAKGVVPGSTAPLEFLHITFQCFFAAFYLALSADVPPALLRHLFNCGRPGNSPVARLLPTLCIQGSEGKDSSVAALLQKAEPHNLQITAAFLAGLLSREHWGLLAECQTSEKALLRRQACARWCLARSLRKHFHSIPPAAPGEAKSMHAMPGFIWLIRSLYEMQEERLARKAARGLNVGHLKLTFCSVGPAECAALAFVLQHLRRPVALQLDYNSVGDIGVEQLLPCLGVCKALYLRDNNISDRGICKLIECALHCEQLQKLVLFNNKLTDGCAHSMAKLLACRQNFLALRLGNNHITPAGAQVLAEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHIQDEGVCSLAEGLKKNSSLKILKLSNNCITYLGAKALLQALERNDTILEVWLRGNIFSLEEVDKLGCRDIRLLL
What is the function of this protein?
Pattern recognition receptor (PRR) that detects bacterial peptidoglycan fragments and other danger signals and plays an important role in gastrointestinal immunity.  Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3, INAVA and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling.  This in turn leads to the transcriptional activation of hundreds of genes involved in immune response.  Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages.  Component of an autophagy-mediated antibacterial pathway together with ATG16L1.  Plays also a role in sensing single-stranded RNA (ssRNA) from viruses.  Interacts with mitochondrial antiviral signaling/MAVS, leading to activation of interferon regulatory factor-3/IRF3 and expression of type I interferon.  Besides recognizing pathogens, participates in surveillance of cellular homeostasis through sensing and binding to the cytosolic metabolite sphingosine-1-phosphate and then initating inflammation process.
What are the official names of this protein?
Nucleotide-binding oligomerization domain-containing protein 2, Caspase recruitment domain-containing protein 15.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Basolateral cell membrane.
Protein: RL29_HAEIN
Sequence: MKAQDLRTKSVEELNAELVNLLGEQFKLRMQTATGQLQQTHQAKQVRRDIARVKTVLTEKAGE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: LIS11_PARTE
Sequence: MVLTARQRDELNQAIHQYLLISYQQSAQLFKTEAAVKDGQIEADLLEKKWNSIVRLSKRVITLEQQVEQLNEQLAQAQAGKIQFNKSDDEQRLTPIEKFKLEGHRAGVNCVAFHPQYQILGSASDDGSIKLWDYESGHFEKTLKGHTSNVNCLAFDPTGKYICSASSDLSIKIWELKNHTCVKTLIGHEHSVSTVQFSDHGDFILSASRDKNIKLWEVATGFCKKTFSEHQEWVRCAVFSNDEKQIASCSQDQMIYIWVIDSGQVLHQLSGHEHVVEQVKYIPEHGAKQILTQQQQQNIQTINLLVSVSRDKEIKIWNTILGTNLFTLSGHDNWVNGVSFHPDGVHMLSVSDDKTIRVWNLKEQKQKKKIENAHDKFILKCEINKFIFATCSVDQTIKLWLLS
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes.
What are the official names of this protein?
Lissencephaly-1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the plus end of microtubules and to the centrosome.
Protein: TMCA_YERPD
Sequence: MTNPIVASQPQMAQQGIRRLLILSGQADWSRQQAIMLRQHLAGDWLWLSEQPPEGVNSISPTAARTLLGQENLHGVFDATDGLNIEALAIVAGTLRAGSWLLLLVPEWDDWPQRPDKDSLRWSEQPAPIVTANFIRHLQRQFLADPDVVLWQQDRPLILPAVGSRPCWQQPDGSPTAQQQHILQRLMQADSGIWVLTAARGRGKSTLAGMLVTHWQGACWVTGPGKAATQVLNQQAGERARFWAPDALLDYCQRHDVSDIDWLLIDEAAAIPTPLLSALLAYFPRALLTTTVQGYEGTGRGFLLKFCATLGDWHHLTLTDPIRWATDDPLERVMDNAMLFHDELLGNHPLPKRPPVAQIEIPLYEQRDWRDNPELLRRFYGLLSTAHYRTTPLDLRRLMDAPGMHFSAARVADAVIGALWLVDEGGLSEALALDVWAGRRRPRGNLVAQSLAAHSGQWQAPTLLSRRISRVAVTAAWRQQGIARRMIAAEQAHARQQQCDFLSVSFGYTAELAHFWHRCGFRLVRIGSHKEASSGCYTAMALLPLSPAGEALCQAAQQQLKRDWYWLQQWIGIPTPVFLRLPEPPEVTLTDDDWRELAGFAFAFRPLEASLPALQRLLLHTELPLSALRHYLQLRTPQSEIINTLGLIGRKALVALWRQEAAEGMAMIDVDKMIMSAKPSARCSTVRLPGRKNLTICQC
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
What are the official names of this protein?
tRNA(Met) cytidine acetyltransferase TmcA.
What is the protein family that this protein belongs to?
Belongs to the RNA cytidine acetyltransferase family. TmcA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF43_GUITH
Sequence: MLFNLTVLVMKTFKFHYKFILLFSNKFRFYLYYYMKTRSNSVLIPYTLNFKQVEAEMSLAEHLEEIRQRAFWSFSVLTTMIISCIIFVKNIVKTLQEPAAGIKFLQFAPGEYFFASIKVAAYSGILISSPFIVYQILLFVLPGMTKDERKTLLPIIIGSMILFLLGLIFGYYILVPASLNFFIKYGSDVVEPFWSFEQYFEFILVLLFGTALAFQLPVLQLVLGFLRIVSGKTMFSIWRYVILLSTVVGAVLTPSVDPLTQILLSSIILILYFGGASLVLVVEGSQKNNN
What are the official names of this protein?
Uncharacterized tatC-like protein ycf43.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: PAC_KLUCR
Sequence: MKNRNRMIVNGIVTSLICCSSLSALAASPPTEVKIVRDEYGMPHIYADDTYRLFYGYGYVVAQDRLFQMEMARRSTQGTVSEVLGKAFVSFDKDIRQNYWPDSIRAQIASLSAEDKSILQGYADGMNAWIDKVNASPDKLLPQQFSTFGFKPKHWEPFDVAMIFVGTMANRFSDSTSEIDNLALLTAVKDKYGNDEGMAVFNQLKWLVNPSAPTTIAARESSYPLKFDLQNTQTAALLVPRYDQPAPMLDRPAKGTDGALLAVTAIKNRETIAAQFANGANGLAGYPTTSNMWVIGKNKAQDAKAIMVNGPQFGWYAPAYTYGIGLHGAGYDVTGNTPFAYPGLVFGHNGTISWGSTAGFGDDVDIFAEKLSAEKPGYYQHNGEWVKMLSRKETIAVKDGQPETFTVWRTLDGNVIKTDTRTQTAYAKARAWAGKEVASLLAWTHQMKAKNWPEWTQQAAKQALTINWYYADVNGNIGYVHTGAYPDRQPGHDPRLPVPDGKWDWKGLLSFDLNPKVYNPQSGYIANWNNSPQKDYPASDLFAFLWGGADRVTEIDTILDKQPRFTADQAWDVIRQTSLRDLLRLFLPALKDATANLAENDPRRQLVDKLASWDGENLVNDDGKTYQQPGSAILNAWLTSMLKRTVVAAVPAPFGKWYSASGYETTQDGPTGSLNISVGAKILYEALQGDKSPIPQAVDLFGGKPEQEVILAALDDAWQTLSKRYGNDVTGWKTPAMALTFRANNFFGVPQAAAKEARHQAEYQNRGTENDMIVFSPTSGNRPVLAWDVVAPGQSGFIAPDGKADKHYDDQLKMYESFGRKSLWLTPQDVDEHKESQEVLQVQR
What are the official names of this protein?
Penicillin G acylase, Penicillin G amidase, Penicillin amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S45 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YIDD_CELJU
Sequence: MVWAGVKLLHGYRYLLSPWIGNQCRFYPSCSHYAEEALKTHGFLAGIYLTARRLIKCHPWHPGGIDPVPEHEATCCSHTHPTHGKH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACP_DESHY
Sequence: MSVFDKVKSIVVDQLGVEEDEITLETTFADLNADSLDIVELIMALEEEFDLDIPDEDAEKIRNVGDAVNYIKENQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYB_CHICK
Sequence: MARRPRHSIYSSDDDEEDVEMYDHDYDGLLPKAGKRHLGKTRWTREEDEKLKKLVEQNGTEDWKVIASFLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQESSKAGLPSATTGFQKSSHLMAFAHNPPAGPLPGAGQAPLGSDYPYYHIAEPQNVPGQIPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQALPTQNHTANYPGWHSTTVADNTRTSGDNAPVSCLGEHHHCTPSPPVDHGCLPEESASPARCMIVHQSNILDNVKNLLEFAETLQLIDSFLNTSSNHENLNLDNPALTSTPVCGHKMSVTTPFHRDQPFKTQKENHVFRTPAIKRSILESSPRTPTPFKNALAAQEIKYGPLKMLPQTPTHLVEDLQDVIKQESEESAIVAGLHESGPPLLKKIKQEVESPTDKAGNFFCSNHWEGENLNTQLFTHASTMEDVPNLLTSSILKMPVSEEEGSFHKAFAVPRNRPLASPMQHLNNAWESASCGKTEDQMALTDQARKYMAAFPTRTLVM
What is the function of this protein?
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'.  Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
What are the official names of this protein?
Transcriptional activator Myb, Proto-oncogene c-Myb.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14Z_MYCTU
Sequence: MAKKALVNKAAGKPRFAVRAYTRCSKCGRPRAVYRKFGLCRICLREMAHAGELPGVQKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RS12_CALS4
Sequence: MPTVNQLVRFGRQSVKKKSAAPALQGNPQKRGVCVVVRTTTPKKPNSALRKIARVRLTNGIEVTAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYKIIRGALDAAGVANRKQARSRYGAKKPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MSCL_MYCLB
Sequence: MFRGFKEFLSRGNIVDLAVAVVIGTAFTALITKFTDSIITPLINRVGVNQQTNISPLRIDIGGDQAIDLNIVLSAAINFLLIALVVYFLVVLPYTTIRKHGEVEQFDTDLIGNQVVLLAEIRDLLAQSNGAPSGRHVDTADLTPTPNHEPRADT
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCAP_I77AG
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYIQMCTEIKLSDYEGRLIQNSITIERMVLSAFEERRNKYLEEHPSAGKDPKKTGGPIYRRRDGKWVRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAIKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRTAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRLVPRGQLSTRGVQIASNENMEAMDSNTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNNEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LRC10_MOUSE
Sequence: MGNTIRAFVAFIPTDRCQSYVVGDLREMPLDRMVDLSGSQLRRFPLHVCSFTELVKLYLSDNHLHSLPPDLAQLQNLQILALDFNNFKALPRVVCTLKQLCILYLGNNKLCDLPDELSLLQNLRTLWLESNCLTRLPDVVCELSLLKTLHAGSNALRLLPGQLRRLRELRTIWLSGNQLADFPSVLLRMPFLEVIDVDRNSIRYFPSLAHLTNLKLVIYDHNPCRNAPKVGKGVRRVGRWAEETPEPDPRKARRYALAKEENQEPPPPLLPSSS
What is the function of this protein?
May play important roles in cardiac development and/or cardiac function.
What are the official names of this protein?
Leucine-rich repeat-containing protein 10, Heart-restricted leucine-rich repeat protein.
Protein: TRAY3_ECOLX
Sequence: MSRNIIRPAPGNKVLLVLDDATNHKLLGARERSGRTKTNEVLVRLRDHLNRFPDFYNLDAIKEGAEETDSIIKDL
What is the function of this protein?
Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell.  It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations.  Part of the relaxosome, which facilitates a site- and strand-specific cut in the origin of transfer by TraI, at the nic site.  Relaxosome formation requires binding of IHF and TraY to the oriT region, which then facilitates binding of TraI.  Also positively regulates tra gene expression (By similarity).
What are the official names of this protein?
Relaxosome protein TraY.
What is the protein family that this protein belongs to?
Belongs to the TraY family.
What are the subcellular locations of this protein?
Cytoplasm.