PharMolix/UniProtQA huggingface dataset:
Protein: PIKP1_NPVAC
Sequence: MSCILTALCKKGQANLNSLIKLQNKKVKNYYVKNNETAIDKMLCIAADIKGQVEQLELVNQYLGAPESEKLDFVYDCSDLDINEKDLKSLCLTKNIAYFTQKYNAPTVLKAQAAVYDSFIKHSELFINAICQMDEKQQVNNFCLDELVKLKLIAIKHLCALEYVIENSI
What is the function of this protein?
Plays a role in the stimulation of the viral kinase PK1 function in very late transcription and in expression of genes required for budded virus production.
What are the official names of this protein?
Protein kinase-interacting protein PIKP1, PIKP1.
Protein: UPPP_BORAP
Sequence: MINILNAIILGIVQGITEFLPVSSSGHLLLFRHFIHLKLPIIFDIYLHFATVLVIIIYYRQRISELFSTFIRFSLRKTNKSDLTNLKLISLILIITIVTGVVGTFISKYERMFTLPFILINFIITGILILMLEFKFFKIDFKDNILLVGIFMGLMQGLGAFPGISRSGITIFSATVLGFNRKSAFEISFLSLIPIVFGAILLKHKEFYDIFMVLNFFEINLGALVAFVVGIFSINLFFKMLNNKKLYYFSIYLFALSITVCYFV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIG_MICAN
Sequence: MKVIQEKLPASQIGLEIEIPAETTKNTHEQVVKNLAKSVNIPGFRPGKVPRQILLQRLGTKAVKAAVIEELIENCLESALKQEGIESLGNPQLLSKFEDLIAAYEPGKALTFSVSLDVAPTIILGDYENLSVTAEETVYDPESVENWFKERQEQLATLVPVEDRGAQLGDVAIVDYRGKSAETGEDIPDIDGEDLRVDMEAGRFIEGMVEGIIGMKPEEVKEMTLTFPEDYPKEDVAAKAVIFTITMKELKAKELPELDDDFAQEVSDQETIAELRASLEKRFQEQAEKETKESIDDALTKELVKGATLDLPETLIEKEVTHILTQSFMQFQQMGLDVNQLFTKDNIPKMRENARPDAIESLKETLVVQELAKVAGIEVSPEAVAEKIANIMSQLSDRDIDMQRLEQVITEEMLAENTLEWLKEKATITLVPKGSLEEETSEEEETEETLAAAAVEVLAAEEEP
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: NACB_GIBZE
Sequence: MSDVQERLKKLGLGARTGTGKGTPRRKVKRAPARSGADDKKLQLALKKLNTQPIQAIEEVNMFKQDGNVIHFAAPKVHAAVPSNTFAIYGNGEDKELTELVPGILNQLGPDSLASLRKLAESYQNLQKEKGEDDDEIPDLVEGENFEGEPKVE
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  EGD1 may act as a transcription factor that exert a negative effect on the expression of several genes that are transcribed by RNA polymerase II.
What are the official names of this protein?
Nascent polypeptide-associated complex subunit beta, NAC-beta, Beta-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: SDHD_HISS2
Sequence: MKIQHLMQDPFIQKLMRFEEVMWFNPKSAGVKTGLSYVGLDVSDTQQAAERLQRFAPYFCRAFPETQKTKGILESELVSIDKMKSALIDHYHMPIQGRLLLKKDSHLPISGSIKARGGIYEVLAYAEKLALEHHLITESDDYSQLCDEKIKDFFSRYSIAVGSTGNLGLSIGIMGAVLGFKVSVHMSADAREWKKQKLRSYGVNVVEYTQDYGVAVAQGRKAALSDPNCFFIDDENSTTLFLGYSVAGQRLKQQFLEQGIKVDENHPLFVYLPCGVGGGPGGVAFGLKLAFGDYVHCIFAEPTHSPCMLLGVYTGLHDKIAVQDLGIDNITAADGLAVGRASGFVGRAMEHLLDGFYTIEDQKLYDLLGLLHKTENIQLEPSALAGMIGPLHINHSDYLRRYHITQEQLANATHIVWATGGGMVPDVEMQKYLSLGRF
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: CDC5L_BOVIN
Sequence: MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKKKRGVDYNAEIPFEKKPALGFYDTSEENYQTLDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPASQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSHGSEGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKTVGFGTNNAEHIAYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAYLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQHRYADLLLEKETLKAKF
What is the function of this protein?
DNA-binding protein involved in cell cycle control.  May act as a transcription activator.  Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes.  Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.  The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
Cell division cycle 5-like protein, Cdc5-like protein.
What is the protein family that this protein belongs to?
Belongs to the CEF1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=May shuttle between cytoplasm and nucleus.
Protein: RNFH_NEIG1
Sequence: MLEIEIVYGLPDRQVLKTMQLAEGTTVRTAALQSGLDGIFENLNLHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPKEARRKRVQNQEE
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: ENGB_FLAPJ
Sequence: MKINTAEFIISNSIVSLCPQEHLPEYAFIGRSNVGKSSLINMLTNHKSLAKTSGRPGKTQLINHFKINNNWFLVDLPGYGYAKVSKKTKEVFQQFITDYFEKREQLVCAFVLIDIRHEAQKIDLEFITYLGEIELPFCIVFTKADKISKGKVAQHVAAYRTALLKNNWEEMPHHFVTSATEHTGKESLLSYIDEVNQDIFKQNGF
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SECA_LEPIC
Sequence: MNMIQNILRVVFGSKFERDLKKLIPIVRQINSLEESIKGMDDSTLSSQTKKFKERIVQGESLDSILPEAFATVREVSLRTMGMRHFDVQMMGGIALHGGNISEMKTGEGKTLTSTLAVYLNSLAGNGVHVVTVNDYLAKRDANWMKPIYDFLGISVGVIQHDMDHEQRKVAYAADITYGTNNEFGFDYLRDNMVSHKDHKVQRSHFFAIVDEVDSILIDEARTPLIISGPSDEATDKYVRVNKIIPKLSEGEDFEVDEKARNVLLTEKGVSHVEEILSIENLYAPENVDLVHHVHQALKAHKIFRVDKDYVVQQGQVVIIDEFTGRPMEGRRYSDGLHQAIEAKENVTIAKESQTLASITFQNYFRMYDKLAGMTGTADTEAEEFKKIYNLDVIVIPPNVSVQRKDSPDRVYRTEKEKFQAILTEIRELQSKKQPVLVGTISIEKSEVLSKMLASAGIQHNVLNAKFHQKEAEIVANAGKPGAVTIATNMAGRGTDIVLGGAQLYKENLETWKDEDEIVKQFKESILRQNLEYAESLMQKMDSGTKQKRASEILSSVKIWKKNHEEVLAAGGLHILGTERHEARRIDNQLRGRSGRQGDPGSSRFYLSLQDDLMRIFGSDRISGLMKWANMPEGQEIESKMVSNAIARAQKRVEGHNFDIRKHLLEYDDVMNRQRIVIYKMRNEVLENEDISPLISGFIEETVENQIVTHCEGNNPSAWNLESLKEWSDGLDLNLQIDEVEFKKSKNPQLSLFEKVSSTAKLKYESKAEKIGKDIWKLLERNIFLDILDHRWKEHLYSMDHLREGIWTVGYSERNPLVEYKLQGFRMFDTAIENLKNEIVNFIFRVEVSENSKLPEEKKEYKKVGQEITGGFQEFSGGNLNRSQSNGSSVTVTTSSGGGTERKTSRRRKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: F104A_HUMAN
Sequence: MGGRGADAGSSGGTGPTEGYSPPAASTRAAARAKARGGGRGGRRNTTPSVPSLRGAAPRSFHPPAAMSERLRPRKRRRNGNEEDNHLPPQTKRSSRNPVFQDSWDTESSGSDSGGSSSSSSSSINSPDRASGPEGSLSQTMAGSSPNTPQPVPEQSALCQGLYFHINQTLREAHFHSLQHRGRPLT
What are the official names of this protein?
Protein FAM104A.
What is the protein family that this protein belongs to?
Belongs to the FAM104 family.
Protein: LGT_ECOBW
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EX7L_CLOB1
Sequence: MHIKTLTVSQLNRYVKNTLDADFILNNASVKGEISNLKIHSSGHIYFSLKDGGSKINCVMFKSYAYNLKFAPENGMDVVALGNVSVYEKEGSYQLYVKDMKREGIGDLYVAFEKLKEKLKEEGLFDDVHKKEIPKFSKKVGVITSPTGAALKDIINVTKRRNKGIELLIYPALVQGTDASRTLIEGIKILNKVEDVDIIILARGGGSIEELWAFNNEELAYAVYNSKKPIITGVGHETDFTIVDFVSDRRAPTPSAAAEIAVFDREVLINEILNYKYNIKNYMENIIKEKRNYLNLYKQKIEANSPTNIIVNEYKNIDNLKELLNMKIEGKLNKEKNNLSRLSSLLEAHNPLNVLKKGYTLIEDEGNNLITEKEALKELNKINIIFKDGRAKLSIEYIEEF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_LIMRD
Sequence: MSMSDPIADFLTRIRNANMAQHESVEAPASKMKKDIAEILKNEGFIRDVEYVDDNKQGIIRVFLKYGNDGQRVISGLKRISKPGLRTYVKSDAVPKVLNGLGIAIISTSEGVVTDKVARAKKIGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: EX7S_CAUSK
Sequence: MISPQDLEGMSFEQALARLEQIVGELESGKAELERSIEIYEDGAALKAHCEKKLEAARLKVEKIVLGQGGAVSAEAAEFN
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_ALTMD
Sequence: MKKQVLRIGVGGPVGSGKTALLRQLCLSLRDKYNMAVVTNDIYTREDAEFLTKNDALAADRIIGVETGGCPHTAIREDASMNLAAIDELQARHNDLDFVLVESGGDNLSATFSPELSDLTIYVIDVSAGDKIPRKGGPGITKSDLLIINKIDVANLVGASLEVMDADTKKMRGDKPFIFSNMKTQQGLADIISFIEKEGMLSL
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAL_MOUSE
Sequence: MAGRQTGWSQAALLQFLLGMCLTVMPPIQARSLRFVTLLYRHGDRSPVKTYPKDPYQEEKWPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNEVQHFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNRSIQNAQFLNMVANETGLTNVTLETIWNVYDTLFCEQTHGLLLPPWASPQTVQRLSQLKDFSFLFLFGIHEQVQKARLQGGVLLAQILKNLTLMATTSQFPKLLVYSAHDTTLVALQMALNVYNGKQAPYASCHIFELYQEDNGNFSVEMYFRNDSKKAPWPLILPGCPHRCPLQDFLRLTEPVIPKDWQKECQLANDTADTEVIVALAVCGSILFLLIVLLLTILFRMQAQPPGYHHVADREDHA
What are the official names of this protein?
Lysosomal acid phosphatase, LAP.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass membrane protein; Lumenal side. Lysosome lumen. Note=The soluble form arises by proteolytic processing of the membrane-bound form.
Protein: PLB5_SCHPO
Sequence: MKLSSFGLFLALQLLPALGLPSRIDEVDVSDPELIGLLKPDNVDKPANSIPLSKRSTSPSYAPYTVACPSGSLLRPASDGLSTGEQEFVDKRVSKVNSALESFISKTGLKIDTKSVLNDTDGPRLGIAISGGGFPAMLTGAGAINAFDARNGNTTSLGGILQSSMYLTGLSGGSWLVGSVAVNNFANITFLHDDVWNLDHSLFAPYDDAFENFYIYQEWFEQVLQKKNAGFNVSITDLWGRALALKLVNPLTGGANTTFSSVTNETWFQDGEFPFPIIIADNVIEGETVIPLNDTVFEFTPIEFGTWDTGVESFIPMEYTGTHLINGIPLNESCVRNFDNAGFLMGTSSNVFSGILPATNASLTASNNTFNNAVLSFLEMLAEDQLDVGLYPNPYQGYGNASNTTTTNPLEPYPIIELIDGGSDSEGIPFWPLLHPQRDVDVIFAIDGGYQSATSGWPDGSSLVSTYERVLATNSSGVRGFPYIPDTNTFLALGLNTHPTFFGCDGRNTTAGNHTVNDDTPPLVVYFPNYPWTMYANVTTYTVQLEDTLSSGMIENAAVAATQNNSDSFAVCVACALVQRSLERKNMSTPSQCASCFNQYCWNGTIASTTVTTYAPTVLSAKI
What is the function of this protein?
Catalyzes the release of fatty acids from lysophospholipids.
What are the official names of this protein?
Putative lysophospholipase C1450.09c, Phospholipase B.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: KHSE_BACLD
Sequence: MTEADMLFSVTVPGSTANLGPGFDSVGMALSRYLRLSVFPHDEWRFEAETEVVAGIPEGTDNLIYQVAKRTAAHFGKELPPSLVKVWSDIPLARGLGSSAAAIAAAVELANELADLKLSDREKLHFASLEEGHPDNAGASLFGGLVIGLHEEDETEMVSMKDIDLDVVVVIPFYEVLTKDARDVLPESLSYPKAVEASAVSNMLVAGLMAKDWKLVGRMMQKDLFHQPYRRALVPELSKVEHEAGQNGAFGTALSGAGPTILSFIEKGKGEALRNQLASKFPHCEVDCLYVPDTGIIVERKSVNSV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_ALIB4
Sequence: MKKIVLLMLAIAGIAFAADEAVVNETLKAYSVVAAGIGLGLAALGGAIGMGNTAAATIAGTARNPGLGGKLMTTMFIALAMIEAQVIYALVVAMIALYANPFLG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NHAB_PSEA6
Sequence: MQQSTIGAVYSNFLGQAPDWYKKSIIAFLIFNPILFMADPYIAGWALVLEFIFTLAMALKCYPLQPGGLLLIEALFIGMTSPEHMKHEIVVNIEVVLLLVFMVAGIYFMKDMLLFMFTKLLLKLKNKIALSMSFVAASAFLSAFLDALTVVAVIIAVGMGFYSIYHKVASGKEFHSDHDHTSDDHVDHPKRQDLEDFRAFLRNLMMHAAVGTALGGVMTMVGEPQNLIIADKASWNFGEFFVRMSPVTIPVFFAGIATTFALEKFKIFSYGAQLPQVVRDILTAHSHQQEATRTKQDSAKLWIQGFIGIWLVIGLAGHFAAVGLIGLSIIVLATSMNGIIDEHSIGKAFEEALPFTALLCVFFGVVAVIIDQGLFTPVIDWVLTFEGRSQLVMFYLANGALSMVSDNVFVGSVYITEVAAALEHGHITRDEFDMLAVAINTGTNLPSVATPNGQAAFLFLLTSAIAPLLRLSYGTMVYMALPYTIVLTIVGLAATYFGLGDLTNWLYDMHLIEHHSATLGAEAAAH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRVP1_HYDHA
Sequence: MIAFIVLLSLAAVLQQSSGTVDFASESSNKKDYRREIVDKHNALRRSVKPTARNMLQMKWNSRAAQNAKRSADRCTFAHSPEHTRTVGKFRCGENIFMSSQPFAWSGVVQDWYDEIKNVVDGIGAKPPGSVIGHYTQIVWYKSHLLGCASAKCSSTKYLYVCQYCPAGNISSSIATPYKSGPSCGDCPSACVNGLCTNPCEYEDTFSNCKALAKKTKCKTEWIKSKCPATCFCHNKII
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein 1, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2179_THEKO
Sequence: MDFERKPLIGMVHLKPLPGSYLYNGDFDSVIEAALRDAVTLEEAGFDAVMVENFGDVPFPKYADKTTVASLAVVAKAIRDEVSLPLGVNVLRNDGIAAYSIAYAVKADFIRVNVLSGVAYTDQGIIEGIAHELAMLRKRLPSEIKVFADVHVKHAVHFGDFEDAFLDTVERGLADAVVVSGKATGRPVDVDKLALAKEISPVPVIVGSGTSYDNLPELWKYADGFIVGTWIKRDGRVENEVSLERARKLVELAKELRQSSI
What are the official names of this protein?
Uncharacterized protein TK2179.
What is the protein family that this protein belongs to?
Belongs to the BtpA family.
Protein: DAPB_ECOL5
Sequence: MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIA10_PONAB
Sequence: MRGYLVAIFLSAVFLYYVLHCILWGTNVYWAAPVEMKRRNKIQPCLSKPAFASLLRFHQFHPFLCAADFRKIASLYGSDKFDLPYGMRTSAEYFRLALSKLQSCDLFDEFDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDPFIIRTAAYELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAGFKYNFSDLKSPLHYYGNATMSLMNKNAYHNVTAEQLFLKDIIEKNLVINLTQD
What is the function of this protein?
Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant.  Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids.  Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (By similarity).
What are the official names of this protein?
Type 2 lactosamine alpha-2,3-sialyltransferase, CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI, ST3Gal VI, ST3GalVI, Sialyltransferase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: MNHC2_STAA1
Sequence: MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGTYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDAK
What are the official names of this protein?
Putative antiporter subunit mnhC2, Mrp complex subunit C2, Putative NADH-ubiquinone oxidoreductase subunit mnhC2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LUXS_BIFLO
Sequence: MAEETAEKPVVESFQLDHTKVKAPYVRYIDTETGPHGDVISNYDLRLTQPNEQAIPTGGLHTIEHTIAVLLRERIPGYIDCSPFGCRTGFHLLTWGTHSTEDVAKALKESLEFIAYKATWDDVPATTEKSCGNYRDHSLFTAKEWAKLILEEGISSDPFERKVV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: GLMU_BAUCH
Sequence: MLNIKLNIVILAAGKSTRMNSDIPKVLHLLAGKPILQYVIDTAIKLKAKCKSTNIYIVYGYKGELLQQKLAHKQKTFLHWIKQVEQSGTGHAVQQVLPFLGKDEEVLILYGDVPLISFQTLIHLLTTRSKQGLSLLTANLTNPDGYGRILYKEQEVVGIIEHQEANAQQKLISEINTGILAVSSNELKIWITKLTNNNSMNEFYLTDIIALAWQEGKKIHTIHPEKISEINGINDCAQLANLERLYQKEQAESLLRIGVIIADPNRFDLRGELKHGDNIFFDTNVLIEGQVSLGNQVTIGTGCIIKNTVIGDNVIIKPYSIIEEAHLANGSIVGPFAHLRPGSKIEENAYVGNFVEIKKSTLGKKSKVAHLSYIGDANIGKDVNIGAGTITCNYDGANKHQTIIGDNVFIGSDSQLIAPLTIGDGATIGAGTTVTSNVTSNEVIISRIRQFPIINWQRPKKKIRYNIIY
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDC_MYCA1
Sequence: MPVTDAATEPAYTVGDYLLDRLAELGVSEIFGVPGDYNLEFLDHIVAHPRLRWVGNANELNAGYAADGYGRLRGMSALVTTFGVGELSAANAVAGSYAEQVPVVHIVGGPSKDAQGTRRALHHSLGDGDFEHFFRVSREITCAQANLMPATARREIDRVLSEVREQKRPGYILLSTDVARFPTEPPEAALPRYTGGTSPRALAMFTEAAAALIGEHRITVLADLLVHRLQAIKELEALLAADVVPHATLMWGKSLLDESSPNFLGIYAGSASAPAVRTAIEEAPVLVTAGVVFTDMVSGFFSQRIDPARTIDVGQYQSSVAGEVFAPLEMGEALQALAAILTRRGVSSPPVASPPAEPLPPPPPREQPLTQKMVWDRVCTALTPGNVVLADQGTSFYGMADHRLPQGVTFIGQPLWGSIGYTLPAALGAAVAHPDRRTVLLIGDGAAQLTVQELGTFAREGLSPVIVVVNNDGYTVERAIHGETAPYNDIVGWKWTEVPNSLGVTDHLAFRVQTYGELDDALTAAARHQDRMVLVEVVLPRLEIPRLLVELVRPTSPDGSPRR
What is the function of this protein?
Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.
What are the official names of this protein?
Alpha-keto-acid decarboxylase, KDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: COBS_PSEU2
Sequence: MLPFWIALQFLGSLPIRLPGMPSPEELGRSLLFYPLVGAVFGTLLLGFNTLLSGAPLMLHAALVLTAWVLLSGGLHLDGLADSADAWLGGFGDRERTLKIMKDPRSGPIAVVTLVLVLLLKFAAILALIESHASVWLLLAPVIGRAAMLGLFLGTPYVRSGGLGQALADHLPRGPGRKVLLATAIACVLLAGWSGVAVLLVCAVCFFWLRQLMMRRLGGCTGDTAGALLELLELAVLLTLALL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.