PharMolix/UniProtQA huggingface dataset:
Protein: HOSA_SULIL
Sequence: MIKVGILDSTLREGEQTPGVIFTVDQRVEIAKALSDLGVSMIEAGHPAVSPDIYEGIKRIVKLKKEGIITSEIVGHSRAVKRDIEIAAELEVNRIAIFYGVSDLHLKAKHKATREEALRTIAETISYAKNHGVKVRFTAEDGSRTDFDFLVTVSKTARDAGADRVSIADTVGILYPSKTKELFSALTREVPNLEFDIHAHNDLGLAVANALAAIEGGATIIHATVNGLGERVGIVPLQQIAAAIKYHFGIEVVKLDKLQYVSSLVEKYSGIPMPPNYPITGDYAFLHKAGVHVAGVLNDPRTYEFMPPETFGRTRDYTIDKYTGKHALRDKYEKLGVKISDAEMDQILAKIKSNTTIRFYRDVDLLELAEEVTGRVLKPRPPEQIEALISVKCDSNVYTTSVTRRLSVINGVKEVMEISGDYDILVKVQAKDSNELNQIIESIRATKGVRSTLTSLVLKKM
What is the function of this protein?
Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate.  Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
What are the official names of this protein?
Homocitrate synthase, HCS.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
Protein: PUR2_HELPJ
Sequence: MKDNNNYNVLIVGNKGREYALAQRLQQDERVNALYFCLGNGGTQDLGENLECEHYEHIVELALKKQIHLAIISEEEPLILGLTEMLEKAGILVFGASKEAAKLEASKSYMKAFVKECGIKSASYFETNDLKEALNYIQNASFPLVIKALNKNTSIVHHQEEALKILEDALKQSNEPVIIEPFLEGFELSVTALIANDDFILLPFCQNYKRLLEGDNGVNTGGMGAIAPANFFSNELEEKIKNHIFKPTLEKLQADNTPFKGVLLAEIVIIEEKGVLEPYLLDFSVRFKDIECQTILPLVENPLLDLFLATAKGELHSLELVFSKEFVMSVALVSRNYPTSSSPKQTLYIDPVDEKKGHLILGEVEQDNGVFESSGGRVIFAIGRGKSLLEARNHAYEIAQKVHFEGMFYRKDIGFKVLDLKEYS
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: DID1_BITGA
Sequence: MIQVLLVIICLAVFPYQGSSIILESGNVNDYEIVYPKKVTVLPTGAMNSAHPCCDPVTCKPKRGEHCISGPCCRNCKFLNAGTICKRGRGDSLHDYCTGVTPDCPRNPNKGESDELEWSAAATGSVLM
What is the function of this protein?
The heterodimer bitisgabonin-1 is a potent inhibitor of the adhesion of the RGD-dependent integrin alpha-5/beta-1 (ITGA5/ITGB1) to immobilized fibronectin.
What are the official names of this protein?
Disintegrin gabonin-1, Bitisgabonin-1.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVC_CHLL3
Sequence: MNVYYEQDADLGRLQGKNIAVLGYGSQGHAHALNLKDSGMNVCVGLRPDSSSCAKAREAGLRVEPVADAVKWADIVMVLLPDQTQKAVYEAEIAPNMVAGNTLAFGHGFNIHYNQIVPPADVDVIMIAPKSPGHLVRRTYTEGNGVPCLIAVHQDATGEAKKTALAWAKGIGGTKAGVIETNFKDETETDLFGEQAVLCGGSAELIKAGFETLVEAGYPEELAYFECMHELKLIVDLYYEGGLSRMNYSVSDTAEYGGMTRGPRLITSAVKAEMKKVLEEVQDGRFAREFIDECNGGYKNLNRLREENSGHAIEKVGAKLRNMMSWLVRK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: DEOC_SERP5
Sequence: MTELTAAAQRALTLMDLTTLNDDDTDEKVIALCRQANSPAGHTAAICIYPRFIPAARKALREQGTPDIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALIAGNEQVGFELVKQCKQACLAANVLLKVIIETGELKQANLIRKASEIAINAGADFIKTSTGKVPVNATLESAELMMSVIRDMGVAKTVGFKPAGGVRTAEDALHYLQLADRILGEGWADARHFRFGASSLLASLLATLGHGAEPSGSGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EBPS_STAHJ
Sequence: MSKNNFRDDFEKNRQSINSDDQFEDNTNEFDENSNESNDFDNQSDQQFPPRNAQRRQRRRNQATNKNRKFGNQNSDSNANGSLDDRHDEDSFNELQHNQQENHLDNEPIHKDDKLSSEKDFNNDASRRNNRHEASNRKHDKDYDNGSLNDDDRHRRNHEEGIDERQDNRNHKDQQNKKSRHGKDAAIAGGAGVAGAAGAKAAKDKRKKDEHHDSKYNEHKDDRDLNNDNQFDQNRKHDKDLHDDHRDAKDNHSKEEPKKGNKGKKAAVGAGAAGAAGAAGVAAAKHKKDHKNNNHKDNHSHNRDHQDDHRNHKHEDGNDGFQAHNGKKKRGLAGILLPLIALLLILAALAIFIGMYLNNDKKDSNQADNKTEQTANKDNNKDSKDKASNDSDKDKASSDKDKDKATNDDDSNDKATTDNDSSNNSSDDNSSSSDNSTSSNSSDNSSSSDNNGNNSNSDNNNGNSQATSNNSSQSNSNNNQSNSSNSGQQTHVVSGNENLYRIAIQYYGEGTVENVNKLKQANGLSSNNISNGQKLIIPQ
What are the official names of this protein?
Probable elastin-binding protein EbpS.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: OBG_MESHJ
Sequence: MRFVDYVSIEVVAGKGGDGIISFRREAHVDKGGPDGGDGGWGGSIYFVGDSGMNTLLPFYQTKKIFGYNGENGRPKRQTGANGKDIFIKVPLGTQVFLKKSLICDIILEKKYLIAKGGRGGLGNFHFRNSKNKAPRISENGELGQNFYLDLQLKVMADIGLVGKPNAGKSTLLSLISNSKPKIANYEFTTLAPQLGVVKIYENSFVTADLPGLIQGASSGKGMGIIFLKHIERCRAIVHVIDFGSDNKNPIKDFIEIKSELEKFNKKLLDLNQIVIANKCDLPNFQFNLANFKRKFPKIKIIKSSLISAKQNEINIIKEKMFGLLGEKQKKLEIQEINTSKIEFNLKAPFLIKSRNNGFFEITGELIQKIIQKIPLNSQENILRFNAKVKKIGLWDELIKKGIKPGDLVRIYEFEFHWN
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH2_RHOP2
Sequence: MADFFMTNLWPLIVVIGQSVLLIVVLLISIAYILLADRKIWAAVQIRRGPNVVGPWGLLQSFADLLKMILKEPMIPSGANKGVFLLAPLVTCVLALSAWAVIPVSAGWVIADINVGVLYILAVSSLSVYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSIGFVIICVLLCVGSLNLTAIVQAQNSQWGVLGWYWLPLFPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYSSTPYMLFVLGEYVAIVTMCAMGTILFLGGWLPPVPYAPFTWVPGIVWFALKVLFMFFMFAMAKAIVPRYRYDQLMRLGWKVFLPLSLAMVVIVAAVLQFAGLAPK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 2, NADH dehydrogenase I subunit H 2, NDH-1 subunit H 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COAD_XANAC
Sequence: MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALSLERRVALAQEALAAHANVEVRGFDTLLAHFVREMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVEALRQVRQSRAQA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BXA4_BOMMO
Sequence: MKILLAIALMLSTVMWVSTQQPQGVHTYCGRHLARTLADLCWEAGVDKRSGAQFASYGSAWLMPYSEGRGKRGIVDECCLRPCSVDVLLSYC
What is the function of this protein?
Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects.
What are the official names of this protein?
Bombyxin A-4, BBX-A4, 4K-prothoracicotropic hormone, 4K-PTTH.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVD_CHLPD
Sequence: MRSDTIKKGFDKAPHRSLLKATGVITSSDDYQKPFIGICNSFNELIPGHAHLQELGRIAKNEVRKAGGIPFEFNTIGVCDGIAMGHIGMRYSLASRELIADSVETVVEAHRLDGIVCIPNCDKITPGMMMAALRVNIPVIFVSGGPMKAGHTPDGKTVDLISVFEAVGRHSTAEITDGELQTIEENACPGCGSCSGMFTANSMNCLSEALGLALPGNGTILASDPRRNELVKEASRKIIDLVRSNTRPRDILSRKALLNAFALDFAMGGSTNTILHTLAIANEAELDFDFSELNALSAKTPYICKVSPATMAVHIEDVDRAGGVSAILLELSKIDGLLDLSAPTVSGKTLGENIAGAEIKDEKVIRTIDNPYSATGGLAVLYGNLAPQGAVVKTGAVSPSMMRHTGPAKVFDCQDDAIKGIMEDIIKPGDVVVIRYEGPKGGPGMPEMLSPTSAIMGRGLGDSVALITDGRFSGGSRGACIGHVSPEAAENGPIAALKNGDMITIDIPARTISVDLSTEAINERIALLPVFEPKIKKGYLARYAQLVTSACTGAILKTSPYCEPK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: YCEH_SALPA
Sequence: MKYELTATEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLTEQEVQEQLDNLVKRHFLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALVTTLLLRGAQTPGELRSRASRMHEFSDMAEVESTLERLASREDGPYVVRLAREPGKRESRYIHLFCGDVDELSLQTSAPESASGDLQSRVEALESEVAELKQRLDSLLAHLGE
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: HFQ_RHIL3
Sequence: MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPMQMFESEEAAS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: Y257_AQUAE
Sequence: MKDKPLKLTVEKLVYGGYGFSRLNGKAVFVRFASPKELVEAKVVKEKKDYTEAVVTKVLISSPARRKAPCPYYGECGGCQIQHLNYEEQLRSKKDILLESLERIGKIKEVPYEGEIPSKKEFNYRVRVQFKIQENRVGFYRWDVKEVVDVEECLLAHERINELIPHIREVLKVIKDLQEVHVNYSPTRDEATLKFVTITHTDEKLLQNILENVLPEWVVGIGDYGKVGNSLVKRYKVGREHIFMDVGKWQYRVSNDSFFQVNYTLWEDFLKEVLDFSESYKKGLDLHCGVGFFTIPLSEQGNFIEGADANPSAIKDAEYNAKINNRDNVIFEEATAFKHLKRRIGEVINLVVVDPPRSGLLREERDLLLKNKPDKIVYISCNPTTFARDLKILTKGGYELKRLKLIDNFPQTYHIESIALLEVKD
What are the official names of this protein?
Uncharacterized RNA methyltransferase aq_257.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: MZM1_ASPTN
Sequence: MASSVPSARSAYRQLLRATRIAFRDDIRVLIAARQEARRNFDSHRRQGIDTPMQINHAIEVANILRHNIVQGVRESEDEAARWELRIHDEIERGDNDSIKVGGKSVKVDKPCSA
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RPOA_LIMRD
Sequence: MIEFEKPNIHKVEETDNYGKFVVEPLERGYGTTLGNSLRRVLIASLPGAAITSMQIDGVLHEFSTVEGVTEDVTQIILNLKKVSLKLDSEDQKNLELDVKGPAEVTASDIQGDNEVTILNPDLHIATVADGAELHIKLTADKGRGYLSANDNKARMDDLAIGVLPIDSIYTPIERVNYTVENARVGQRNDYDKLTLDVWTDGSLTPTEAVSLGAKILTEHLAMFVDLTETAQNAQVMVEKEETHKEKMLEMTIEELDLSVRSYNCLKRAGINTVKELTDRTVSDMMKVRNLGQKSLEEIKLKLNDLGVSFRQDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RS27A_METST
Sequence: MSKKYELYEVKDGKIVRKNPECVRCSHGIFMADHGDRYACGRCGYTQWKNE
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: A6108_ARTBC
Sequence: MQLTQVLAVAILAAGVSAGHRPHRPHSNKLEIQDIKCQSGAPYCCSPDKTKGSTCTKLTGSSVNCDSVVVCCNNNGDKHSPQTCSASVAHPITFVDVDAKFRIDHNKVSHNRVNAKQRRDDKKDYGKNDYGKKDYGKKDYGKKDYGKKEYDPKDHKDYDHKDYDHKDYGHKDYGHKDYGHKDYGHKDYGHDDYGYKGYDDKDYGYKGYDDYY
What are the official names of this protein?
Uncharacterized secreted protein ARB_06108.
What are the subcellular locations of this protein?
Secreted.
Protein: RL3_NATPD
Sequence: MPQPSRPRKGSMGFSPRSRAASEVPRFNSWPDDEGQPGLQGFAGYKAGMSHVVAINDEPNSPREGQEETVPVTVVETPPMRAVAVRAYEDTPYGKRPLTEVWTDEVHEDLERSLSVPEEQSGDIEGDIRTALDEGALADVRVITHTVPGALSSVPKKEPDVMETRVGGGSLSDRVDFALDLVDDGGEHTVTDVFRAGEYTDVAGITKGKGTQGPVKRWGVQKRKGKHARQGWRRRIGNLGPWNPSRVRSTVPQQGQTGYHQRTELNKRLIDLGDDDVSPDGGFVNYGEVDGPYALVKGSVPGPDKRLVRFRPAVRPGDQPRLDPEVRYVSTASNQG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ZA2G_HUMAN
Sequence: MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS
What is the function of this protein?
Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers.  May bind polyunsaturated fatty acids.
What are the official names of this protein?
Zinc-alpha-2-glycoprotein, Zn-alpha-2-GP, Zn-alpha-2-glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPA_BLOFL
Sequence: MFTGSIVALITPMDSKGSIDRMGLKKLVDYHVDNGTSAIVSVGTTGEMSGLTHSEHVDVVMWTIEFSDGRLPVIAGTGSNSTSEAILLTNQFNDSAVSACLSVTPYYNRPSQEGLFQHFRAIAESTNLPQILYNVPIRTGCDLLPITVGRLSTIKNIVGIKEATGNLNRVNQLKRLVNEDFILLSGDDISAVDFMRLGGHGVISVTANVAPKDMSTLCSFVQKNDFKSAYDINNRLIPVHQSLFFDSNPIPVKWACKELGLISYDTLRLPMTSISKEHSVLIRKALEDADLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBLN1_MOUSE
Sequence: MLGVVELLLLGTAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRSGSAKVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGWKYSTFSGFLVFPL
What is the function of this protein?
The cerebellin peptide exerts neuromodulatory functions.  Directly stimulates norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release (By similarity).
What are the official names of this protein?
Cerebellin-1, Brain protein D3, Precerebellin.
What are the subcellular locations of this protein?
Secreted. Postsynaptic cell membrane. Note=Interaction with CBLN3 may cause partial retention in the endoplasmic reticulum.
Protein: DEF3_PAPHA
Sequence: RTCRCRLGRCSRRESYSGSCNINGRIYSLCCR
What is the function of this protein?
Has antibacterial activity against the Gram-negative bacterium E. coli and the Gram-positive bacteria L. monocytogenes and S. aureus.  Has antifungal activity against C. albicans.
What are the official names of this protein?
Defensin-3, PhD3.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL32_NAUPA
Sequence: MAVPKRRNSKTRGAKRRTHYKIKLSSVIKCSNCGAYKRPHRVCPSCGEY
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: DNLJ_FINM2
Sequence: MEKQDRIKYLVDILNKYAYHYYTLDDPLIADSEYDVLYDELVNLEKETGIVLPNSPTNRIGGEVLSGFEKHEHLNTLYSLGKAQSKEEVRNWVDKTIEFVQNYNENHVNKLPKVEFYVEFKFDGLTVNLTYDGGYLVMATTRGNGTIGEVITSQVKTINSIPLKIKDTRLMEIQGEGVMPLSSLENYNKTHEPKLKNARNAAAGALRNLDPAVTRERNLDAYFYNVNYLQDNELETQEEMIKFLGDNYFKLYPYEKHATSFEEVSKFIDEIFELRNEIDVLTDGVVIKVNDFKTREKLGYTNKFPRWAIAYKFEPERFTTIVKEVEWNVGRTGKVTPTALLEPVEIGNVTVKRATLNNIDDIERKQVRLNSEVFVRRSNDVIPEIMGVVNPDQEDTEEIEIPHYCPYCHSELFRDGVHIFCPNSMSCTPQLVKRMVHFASRNAMNIDGLSEKTLEVLLEKLNIKSIEEIYDVKKEQLMQLDGFKEKKSQNLINAIEKSKNVDLANFIFALGIPEIGEKTSFELAQKYKSFDNLREAKFEELIQIEDIGNVIAEEIVEFFHDETISNSIDSLLSKGIKIKNPENIEKKLDNLTFVLTGSLVNYSRKELTDKLSNLGAKVSSSVSKNTDYVVYGEKAGSKLTKAKDLGVKLMTEDELNSFLDNL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: UBE2B_MOUSE
Sequence: MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1.  H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation.  In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination.  Required for postreplication repair of UV-damaged DNA.  Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'.  May be involved in neurite outgrowth.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 B, E2 ubiquitin-conjugating enzyme B, E214K, RAD6 homolog B, HR6B, mHR6B, Ubiquitin carrier protein B, Ubiquitin-protein ligase B.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Note=In peripheral neurons, expressed both at the plasma membrane and in nuclei.
Protein: TXC1D_CUPSA
Sequence: GFGSLFKFLAKKVAKTVAKQAAKQGAKYVANKHME
What is the function of this protein?
Has antimicrobial activity against B. subtilis, E. coli, E. faecalis, P. aeruginosa, and S. aureus.  Has insecticidal and hemolytic activities.  Probably acts by disturbing membrane function with its amphipathic structure.
What are the official names of this protein?
Cupiennin-1d, Cu-1d, M-ctenitoxin-Cs1d, M-CNTX-Cs1d.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ECI2_MOUSE
Sequence: MAAVTWSRARCWCPSVLQVFRLQVAKLHLGRPTMRASQQDFENALNQVKLLKKDPGNEVKLRLYALYKQATEGPCNMPKPGMLDFVNKAKWDAWNALGSLPKETARQNYVDLVSSLSSSSEAPSQGKRGADEKARESKDILVTSEDGITKITFNRPTKKNAISFQMYRDIILALKNASTDNTVMAVFTGTGDYYCSGNDLTNFTSATGGIEEAASNGAVLLRDFVNSFIDFPKPLVAVVNGPAVGISVTLLGLFDAVFASDRATFHTPFSQLGQSPEACSSYTFPKMMGSAKAAEMLLFGKKLTAREAWAQGLVTEVFPESTFETEVWTRLKTYAKLPPNAMRISKELIRKNEKEKLYAVNAEECTTLQARWLSEECMNAIMSFVSRKPKL
What is the function of this protein?
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species (PubMed:24344334).  Has a preference for 3-trans substrates (By similarity).
What are the official names of this protein?
Enoyl-CoA delta isomerase 2, Delta(3),delta(2)-enoyl-CoA isomerase, D3,D2-enoyl-CoA isomerase, Dodecenoyl-CoA isomerase, Peroxisomal 3,2-trans-enoyl-CoA isomerase, pECI.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Peroxisome matrix.
Protein: RL34_SULDN
Sequence: MKRTYQPHNRPRKSTHGFRARMATKNGRNVINRRRAKGRKKLSV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CRCB1_RHOJR
Sequence: MCAVSLTKPVAVVALGGALGASARFLLAELWPGIWTVLLINVVGSLLLGYLAETVGPDRLSRLFLGVGVLGGFTTFSTFAVDAVREDAVTATLYVVATLIPALLAARLGMLAGHRHRLARKAVA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DMA_ECOLI
Sequence: MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLNTDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQDPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFFYCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVERHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPAKK
What is the function of this protein?
An alpha subtype methylase that recognizes the double-stranded sequence 5'-GATC-3' and methylates A-2 on both strands (Probable) (PubMed:12654995).  Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in methyl-directed mismatch repair, initiation of chromosome replication and gene expression.
What are the official names of this protein?
DNA adenine methylase, DNA adenine methyltransferase, Deoxyadenosyl-methyltransferase, Orphan methyltransferase M.EcoKDam, M.EcoKDam.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.