PharMolix/UniProtQA huggingface dataset:
Protein: RL5_CLOBJ
Sequence: MMPRLQEKYEKEVVSALMDKFGYKNIMEVPKLEKIVINMGVGEAKENQKSLEAAVEDLAKITGQKPILTKAKKSVANFKIREDMPLGCKVTLRKQNMYEFADKLINVALPRVRDFSGVSSKSFDGRGNYAIGIKEQLIFPEIEFDKIDKIRGMDIIFVTTAKTDEEARELLRFLGMPFAR
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RPB1_FRG3G
Sequence: MEMFASKSLQVEGLLFGVCSPEEILATSVVEVTKSCLKAETGSVYDPRMGSAGVDDDDALCPTCENTGRECPGHFGHIELAKPVVLFYKETVAWLKRCCHVCGTVGNEPRPFFFAPYSACNACGAQRPLVRLVDAHDPCAIRVTVRRKDGEPETMPPELILATLDRVRDSDVDRVLGRGKGSHVRFHPRRLVMTRMPVLPPCCRPNARQWPDGAMQDDNLSVFVSQIVKVNQRIKALEPDNPAVEGLVAQLRLKTLCFVDNTKGKVMHATNRKPMAGIKERIGKKGGLLRQNIMGKRRNQTGRSVVGPDGTLEVDEVGVPEAIADNLTVPVMVTPFNVSSLEAMMRDGRVSSVEMRDGTVHRPSEWRPSHGDHMETADGSPLGRVTRPSYDARDPSVVLRSWKTGETVTRPPPFSWPKLEPGMTVTRCLVDGDPVALNRQPTLHRNSMLGMRVKRLPGKTIRLNLSVTSGFNMDFDGDEGNLYLPQGPQARSETMLLMNPKSVIMSARGPHAEVSLVQDGVLGCHLMSLNSEIPCPPEELATCLMEVHGCEGWDVRDVEKGATPRDLLSSVLPSTLTVDCGGGCRIESGKIVSGHLTKSAVKKIVRAVCLENGGDAAGKLVDKLQFLTNAWLSHRPFSVGYSDCLTERPEETVRMVADAVCSKILEAEAADDEDGVSVALCGARDRGQAVTCAALTPDNRMAVMSRAQSKGDMFNLTQIAGLLGQQYVGGSRPGKEIDGGRRSLPHYPRVWDLEQTTLKYESRGFVRSSFLKGLNPREVFFHAKSGREGMISTSQMTGVTGYAERKMVKLNEDLVSAYDGTVRDAMGNVVQFVYGGHGMDPQRCWSDGCPVNFKTLAEECSSQECSSQISGLRSPAVTSVEEASLLVPVGLCPGAPDPVRESLFLKHASVILKGAEEHPCEDHSAWRERVARSYAAAVLCPGEAVGVLCAQSIGAKQTQQTLDTFHKAGVWLDDAGSVPFGELLGLSQKPMRRQCVVPLKVDPSTPGDEVRDLVGCSFVRRDLLDLLAVRPSTATVGKTASLELDPVKCFELRISPADVAYAVAEKFPPPHFDVSVSSFGVTLSWSVNYPVDNLFTGLFSVQVGGTPGVESYRLLRGRDGGWVAVTKGTNLGAFLCHPLADWERVRTDDVWDVYETLGLAAAKKRLYELMFSCVGDNLYPAHIKLLTDRMMRRGRPTPIDRYTMRTCEVGPLSRAAFEESLDILTGAGCTAETEHCAGAGARVAAGLPVRAGTGYMGLLCGKGFFDEPVVKVPDADGREYVDYSYSDDESFEW
What is the function of this protein?
Component of the DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Forms the polymerase active center together with the second largest subunit (By similarity).
What are the official names of this protein?
Putative DNA-directed RNA polymerase 008R.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: HSLO_PSEA6
Sequence: MSFDQLHRYLFNQAHVRGELVRLENSYQSILDSYAYPPVIQKLLGELMAATSLLTATLKFEGDIALQLQSDGPVNYAVINGTHDQQLRGVARWDESLAELPTDFSQLFTKGILVITITPEDGERYQGMVALDKPTLAECIESYFQQSEQLATKVILRTQQTDSGAKACGMFLQILPTSSQATATTDTGFEHLAKLTETIKNEELFSLPAEDILYRLYHQEEIEVYPPADIIFKCSCSRERSANALAAVEKAELLDIVATEGAIKMNCQYCHREYRFDEIDVHAIHAGTFAMDTQNDQ
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCR_CAVPO
Sequence: MDLKESVTSSKEVPSSVLGSERRNVIDFYKTVRGGATVKVSASSPSLAAAAQSDSKQRRLLVDFPKGSGSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLPSGETDFRLLEESIANLSRSTSVPENPKNSASAVSGTPTEEFPKTQSDLSSEQENLKSQAGTNGGNVKFPPDQSTFDILKDLEFSSGSPGKERSESPWRPDLLMDESCLLSPLAGEDDPFLLEGNSNEDCKPLILPDTKPKIKDNGDGILSSSNSVPQPQVKIGKEDFIELCTPGVIKQEKLGPVYCQASFSGANIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGEDNLTSLGTVNFPGRSVFSNGYSSPGLRPDVSSPPSSSSTTTGPPPKLCLVCSDELSGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRENCPACRYRKCLQAGMNLQARKTKKKIKGIQQATTGVSQNTSENPNKTIVPATLPQLTPTLVSLLEVIEPEVIHSGYDSTSPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFKNLHLDDQMTLLQYSWMFLMAFALGWRSYKQSNGSLLCFAPDLIINEQRMSLPWMYDQCRYMLYVSSELKRLQVSYEEYLCMKTLLLLSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSLHEIVGNLLNICFKTFLDKTMNIEFPEMLAEIITNQLPKYSNGDIKKLLFHQK
What is the function of this protein?
Receptor for glucocorticoids (GC).  Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors.  Affects inflammatory responses, cellular proliferation and differentiation in target tissues.  Involved in chromatin remodeling.  Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay.  Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.  Mediates glucocorticoid-induced apoptosis.  Promotes accurate chromosome segregation during mitosis.  May act as a tumor suppressor.  May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression.
What are the official names of this protein?
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=After ligand activation, translocates from the cytoplasm to the nucleus (By similarity). In the presence of NR1D1 shows a time- dependent subcellular localization, localizing to the cytoplasm at ZT8 and to the nucleus at ZT20 (By similarity). Lacks this diurnal pattern of localization in the absence of NR1D1, localizing to both nucleus and the cytoplasm at ZT8 and ZT20 (By similarity).
Protein: GLME_CLOCO
Sequence: MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAEKLVLAKKKGITMAQPRAGVALLDEHIELLRYLQDEGGADFLPSTIDAYTRQNRYDECENGIKESEKAGRSLLNGFPGVNYGVKGCRKVLEAVNLPLQARHGTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRLVGFYEEQGVHINREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITVGYGECGNMIQDIAALRCLEEQTNEYLKAYGYNDVFVTTVFHQWMGGFPQDESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMALNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFETGVMDIPFGPSKYNAGKMMPVRDNLGCVRYLEFGNVPFTEEIKNYNRERLQERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase epsilon subunit, Glutamate mutase E chain, Glutamate mutase large subunit, Methylaspartate mutase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmE subunit family.
Protein: ADCY6_HUMAN
Sequence: MSWFSGLLVPKVDERKTAWGERNGQKRSRRRGTRAGGFCTPRYMSCLRDAEPPSPTPAGPPRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGRSCWRRLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAYVALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLWCPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFLWKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLITVLICAVYSCGSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRSCAARMLNLTPADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS
What is the function of this protein?
Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors (PubMed:17916776, PubMed:17110384).  Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells (PubMed:17916776).  Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption.  Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion.  Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion (By similarity).  Signaling mediates cAMP-dependent activation of protein kinase PKA.  This promotes increased phosphorylation of various proteins, including AKT.  Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility.  May contribute to normal heart function (By similarity).  Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol (PubMed:17916776).  Contributes to bone cell responses to mechanical stimuli (By similarity).
What are the official names of this protein?
Adenylate cyclase type 6, ATP pyrophosphate-lyase 6, Adenylate cyclase type VI, Adenylyl cyclase 6, Ca(2+)-inhibitable adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, cilium. Cell projection, stereocilium.
Protein: DAPF_ACIB3
Sequence: MLLEFTKMHGLGNDFMVVDLISQRAYLDTATIQRLADRHFGVGFDQLLIVEPPDVPEADFKYRIFNADGSEVEQCGNGVRCFARFVHERHLTNKTNITVQTKAGIVKPELGQNGWVRVNMGYPKFLPNEIPFVAEEPEALYTLELANDQNISIDVVNMGNPHAVTIVPDVLTADVAGIGPQVESHKRFPERVNAGFMQVIDDKHVRLRVFERGVGETLACGTGACAAAVSGMRRGLLANSVEVELAGGKLQIEWQEGDVVWMTGPTTHVYDGRLDLRYFQG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTCA_SHIBS
Sequence: MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPSWFFCAIASLILTLITRRIIQRANINLAFVGIIYTALFAVYAMLFWLAFF
What are the official names of this protein?
Uncharacterized protein YtcA.
What is the protein family that this protein belongs to?
Belongs to the YtcA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane; Multi-pass membrane protein.
Protein: BHUA_BRUA2
Sequence: MKFTRTLVLVSTSLLATVATSQAQEVKRDTKKQGEVVLKPITIISHGKDNIEATGGTVLTYKDIEKLQPANVSELFSRQSSIAVSGGGGPSKRIHVLGMEQSNLAVSVDGVPQTATSWHHTGSNVIDPAFLKRVEVEAGAAAADSGFGAAAGAIRYETVNALDLLEPGKTFGARIIGSYGTNGRGFSGSTAAYGLKDGFDWLLMLHGTSGHNYKNGDGTEILGTEPAARNILGKAGYEFDGNRIDIGYERSRDKADRLIKMNMGLPGDTEYPLEVARDSVNIKYTRTDATDMWDPEVQFYYNRNDYWRNDYQNRTNGNMILKEDLYGGKLQNTFTIDYGKITAGIDFGKHDYNTDNYGHNDRRYRKFNTQQVGAFTQGRFEFDNGFSLSTGARYDYSRFADWNDEVFSDSGASVNGTLSYKFNEHIEVFAGASRTWLGYVLGDYGYVHARNNAFYTDPTFSPGRARNYKAGVNFGGADWSAGITLFDTRIAGLPNYDSQKLGNDPEEYRSRGFTLNARYIWNYTTIGATFTKAKVTAGDDPVLPNSGSFMPIGDMATLFIDQEIPDYNMKVGATLAWAGRISDEAATAANFYDQPAYTVVNAYAEWNPPAVKNMTLRVGVENLFNENYYERTSFAPSQNRGGIDAVWAPGRTFTFQTAFKF
What is the function of this protein?
Heme transporter playing an important role in stationary-phase iron acquisition and required for maintenance of chronic infection in mice.
What are the official names of this protein?
Heme transporter BhuA, Brucella heme uptake protein A.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RPOE_STAA9
Sequence: MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: PSA4_DICDI
Sequence: MARRYDQRTTIFSPEGRVYQVEYAMTAIRHAGATVGILAKDGIVLAAEKKTTAKLLDSSTSISEKMFKIDEHVVCAVAGITSDANILINYARLSSQRFFYQYQEPMPVEQLVSQICDTKQGYTQYGGLRPFGVSFLYAGWDRHYGFQLYQSDPSGNFAGWKATSIGGENSQVAQSVLRSNYKPDISLKEALQLALKVLTKTMDRSNINSEKLEFSYFTKQGDNVVYHIFTAAELDAFIKETDLEQETEDN
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-4, Proteasome component DD4.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYSG_ECO7I
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: YGFB_ECOLI
Sequence: MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDSSWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRADALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEEIIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH
What are the official names of this protein?
UPF0149 protein YgfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: RSXD_SALAR
Sequence: MVFRIASSPYTHNQRQTSRIMLLVLIAALPGVAAQTWFFGWGTLFQIVLAAVTALFAEAIVLSLRKQSIASRLKDYSALLTGLLLAVSIPPLAPWWMIVLGTGFAIIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPYEIAATTPDMLDTLRMIFTGHTASGGDLTLLRIGIDGISQATPLDTFKTSLRAGHSVKQIMQYPIYSGVLAGVGWQWVNLAWLVGGVFLLWQKTIRWHIPVSFLVTLALCATLGWLFSPGTLASPQLHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGVLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIPA_THET2
Sequence: MKPKFETVELLSPTGEVVELKVVKRGLAQARPEPVDRNKPAWIKAPLPTGPRYQALKAMVRELRLHTVCQEALCPNIGECWTHGTLTVMILGDICTRACKFCAVHTGNPKGLVDPEEPRRVAEAIARMGVRYVVLTSVDRDDLPDGGASHFAATIRAIKERAPGVLVEALTPDFQGDLKAVETVLAANPEVYAQNLETVRRLTPKVRDPRAGYEQTLKVLAHAKKVRPDILTKSSLMLGLGETEEEILEAMRDLRAAGVDILTLGQYLRPTPAHLPVARYVPPEDFKRYEAWGYELGFREVFAGPLVRSSYRADRVFLEATQR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1031_PSEE4
Sequence: MLLHIPGLFDADEISRIREALEQADWADGKVTAGYQSAKAKHNLQLPEGHALAKEIGSALIDRLWCNPQFMSAALPHKVFPPLINCYREGGNFGFHIDNALRQPKGSPERIRTDLSSTLFLNDPDSYDGGELVIQDTFGVQQVKLAAGDMVLYPGTSLHKVNPVTRGARYAAFFWTQSLVREDSQRTLLFEMDNAIRQLTADVPEHPSLLQLTGTYHNLLRRWAEV
What are the official names of this protein?
PKHD-type hydroxylase PSEEN1031.
Protein: YGFS_ECOLI
Sequence: MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADVFLPRLKVQRLDSISAPVMCHQCENAPCVGACPVGALTMGEQVVQTNSARCIGCQSCVSACPFGMITIQSLPGDTRQQIVKCDLCEQREEGPACVESCPTQALQLLTERELRRVRQQRIVASGENPL
What are the official names of this protein?
Putative electron transport protein YgfS.
Protein: RNFA_PSEA8
Sequence: MTELALILVSAILVNNFVLVQFLGLCPFMGVSRKIETAIGLSLATTFVLTLAAMCSHILQRYVLRPLDLEYLRTIGFILVIAVVVQFTEMLVKKTSPLLYRVLGIFLPLITTNCIVLGVALLNANKAEYGFLQATTQGFGAGLGFSLVLVLFAALRERIAIADVPAPFRGAAIGMITAGLMSLAFMGFSGLVRP
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS7_METMP
Sequence: MRAFKVKRDTNETKIQLELNIDGTGKYSITTGIPFFDHVLSSFAKHGSFDLKLDVLGDLEIDDHHTVEDVGIVLGKAFENMEKKNIKRFGWAIIPMDEAKATVSIDIGGRPFVVGNYVPNTERIGSFSTENVVHFFESFSNNAKINLHFEVTGENEHHKVEALFKAFGVAMDMATQIDERKGIVSTKGVI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_CALS8
Sequence: MEKAVNTNTEVKKATATLRYAMISPRKVRIVIDLIRNKPVQEALNILKFIPKRGARFVEKLLKSAIANAENNHNMNVDKLYIAEIYANGGPMLKRIRPRAQGRAFLIRKRTSHITVVLKERE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TVP18_PODAN
Sequence: MTLKEEFQTRNFSIYGQWLGILSMILCFALGLSNMISSIFSLNIVIIAFSILAMVFSFVILFVEVPLLLRICPTSSSFDAAIRKISTNYMRAGAYGVMALVIWLSCISTRTSLIAAAVFLTLTGACYGLAGAKGQAFVGSKTLGGQGVAQMIV
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP18.
What is the protein family that this protein belongs to?
Belongs to the TVP18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: ATPA2_BURP6
Sequence: MTPTPDAPAAADAATGAGWLARRRGALARVALAPVAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGALDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAAHRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSREVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAAPRAMPDGPPRAQADGDRASASRPRPDARGDAARTAPSPQGGAEVNVNAAANVDAEAEARHKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BRMS1_MOUSE
Sequence: MPIQPSGKETEEMEAEGDSAAEMNGEADESEEERSGSQTESEEESSEMDDEDYERRRSECVSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYTEPLGGLQQSLKIRIQVAGIYKGFCLDVIRNKYECELQGAKQHLESEKMLLYDTLLGELQERIQRLEEDRQSLDISSEWWDDKLHSRSSSKAGDAMPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARAAVSPQKRKADGP
What is the function of this protein?
Transcriptional repressor.  Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'.  Promotes HDAC1 binding to promoter regions.  Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B.  Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis (By similarity).
What are the official names of this protein?
Breast cancer metastasis-suppressor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the BRMS1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Protein: RIMO_PARPJ
Sequence: MSATPPIVPTATPKVGFVSLGCPKALVDSEQIITQLRAEGYEISGTYDGADLVVVNTCGFIDEAVQESLDAIGEALNENGKVIVTGCLGAKKSASGSGLIEEVHPKVLAVTGPHALGEVMQHVHTHLPKPHDPFVDLVPAAGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPVADVMLEAENLFKSGVKELLVISQDTSAYGVDVKYRTGFWNGKPIKTRMTDLVGALGELAAQYGAWVRLHYVYPYPSVDEVIPMMAEGPYKGHVLPYLDVPFQHAHPEVLKRMKRPANAEKVMERVKKWREMCPDLTIRSTFIAGFPGETEEQFQTLLDFIREAELDRVGCFAYSPVEGATANELDGALPDEVREERRARFMEVAEEVSAKRIAKKVGKTLKVLVDEINADGGIGRTAADAPEIDGVVYIAPAAKASKRYKVGDFVSVKITGADGHDLWGEV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.