PharMolix/UniProtQA huggingface dataset:
Protein: RPN1_CHICK
Sequence: VFTHVLQPYPEIRPRFPLVGGWKTHYXV
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 65 kDa subunit, Oligosaccharyl transferase 65-I kDa subunit, Ribophorin I, RPN-I, Ribophorin-1.
What is the protein family that this protein belongs to?
Belongs to the OST1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RL22_BURMS
Sequence: MEVKAIHRGARISAQKTRLVADQIRGLPVDKALNVLTFSPKKAAGIVKKVVLSAIANAEHNEGADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL9_RHOPB
Sequence: MEVILLERVAKLGQMGEVVKVKHGFARNFLLPRGKALRATTDNRAKYEHMKADLEARNIEAKAEAIKVAEKIDGRNVVVLRQASETGQLFGSVTVRDIISQFTADGVHIERSQVLLDHPVKTIGKHSISIAVHPEVEVSVSVTVARSALEAERINRGEDISTRQEDQDAAAEALAAAGEFFDPEAHNDGEQEEEAGDK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: FLAE_VIBC3
Sequence: MAMTVNTNVSALVAQRHLNSASEMLNQSLERLSSGNRINSAKDDAAGLQISNRLETQMRGLGIAVRNANDGISIMQTAEGAMQETTQLLQRMRDLSLQSANGSNSAAERVALQEEMAALNDELNRIAETTSFAGRKLLNGQFMKASFQIGASSGEAVQLSLRNMRSDSLEMGGFSYVAAALADKQWQVTKGKQQLNISYVNAQGENENIQIQAKEGDDIEELATYINGKTDKVSASVNEKGQLQLYIAGKETSGTLSFSGSLANELQMNLLGYEAVDNLDISSAGGAQRAVSVIDTALKYVDGHRSELGAMQNRFQHAISNLDNVHENLAASNSRIKDADYAKETTQMIKQQILQQVSTSVLAQAKRQPKFVLFLLRN
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  FlaE is not essential for flagellar synthesis and motility.
What are the official names of this protein?
Flagellin E.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: HIS1_ALKMQ
Sequence: MNVIKIALAKGRLADQSVKLLESIGIDCGPLLDKGRKLIVALPKDHLEVVFVKAPDVPTYVEHGAVDMGIVGKDVLLEANKQLYEVLDLQFGKCKFSVAGSTSMENYPTPHMRVATKYPNIAKNFFQSKGQSVEIIKQEGSVELAPMVGLADVIVDIVETGNTLRENGLMVFEDIVEISARLVLNQVSYKTKHQEIRGLIDRIAEKTGK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_XYLFT
Sequence: MWPLRFNNRFIDVLPCDPEVSLRSRQVLEAWSRVAPTPVPMPCLLAYSSEVAAILNFDAEELVTPRFVEVFSGNALYTGMQPYAVNYGGHQFGQWVGQLGDGRVITLGELLGADGVYYELQLKGAGPTPYSRGADGRAVLRSSIREFLCSEAMHHLGIPTTRALSLIATGDTVIRDMLYDGHPAPEPSAIVCRVAPSFIRFGTFELPASRGDIDLLRRLVEFTIIRDYPHLHGAGETLYADWFAEICTRTAELVAHWMRVGFVHGVMNTDNMSILGLTIDYGPYGWIDNNDLDWTPNVTDVQSRRYRFGAQPQVAYWNLGCLARALAPLFSDAASLQAGLERFRATYLAAERRDAAAKLGFAACFDEDLELFDALRTCMHQAEMDMTLTFLGLADWEPNMPDSLSLWAEAFYDPVKRDAQAPMLRDWLQRYAARLSVDPLPVAERHERMRLANPRYVLRNYLTQQAIECAEQGDLTELHALLEVMRRPYDFQLGREAYAMRRPEWARSRIGCSMLSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: HIS4_CUPNH
Sequence: MLLIPAIDLKDGQCVRLKQGDMDQATVFSEDPAAMARHWVEQGARRLHLVDLNGAFVGKPRNEEAIKAIIAEVGDEIPVQLGGGIRDLNTIERWLDDGLSYVIIGTAAVKNPGFLKDACSAFGGHIIVGLDARDGKVATDGWSKLTGHEVADLARKYEDYGVEAIIYTDIGRDGMLQGINIDATVKLAQSMSIPVIASGGLSNLADIDNLCAVEGEGVEGVICGRAIYSGDLNFAAAQALADKLRDGQ
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_RALSO
Sequence: MATVFSRALGALVLGVACALLAGCASVRPANDLFAGTQDGDATITRYQGRFSARYVQDDAQQSAVGSFLWRERGADVQLELMSPLGQTLAIVSQNRQGATLELPNQPPRRAAEVDTLMQDALGFSLPVSGLRDWLRARPTPGTPARVARDAQSRPETIEQNGWTVHYVAWSDDGDNSTANARVRRLDLDRPQGAGGAPGPLSVRLVLDQ
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL30_YERPA
Sequence: MAKTIKVTQTKSSIGRLPKHKATLIGLGLRRIGHTVEREDTPAVRGMVNLVSYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GCH4_ALKEH
Sequence: MPEAEKLATVSIEDVQARQDSRRIPINKVGIKDIRHPVRVGGRDGQEQHTVANFSMYVNLPQHFKGTHMSRFVQILEGHDTEITVQSFREMLHEVAERLEAESGHIEMAFPLFVRKTAPVTGVQSLMDYQVAFIGEIHEGEPELAIRVVVPVTSLCPCSKEISRYGAHNQRSHVTVTAKTRDLLWVEDLIDLVEEEASCELYGLLKRPDEKYVTERAYENPKFVEDLVRDVAIRLNDEDRVLAYNVTAENFESIHNHSAFAEIEHDKTGEPRR
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: VF602_ASFP4
Sequence: MAEFNIDELLKNVLENPSTEISEETLKQLYQRTNPYKQFKNDSRVAFCSFTNLREQYIRRLIMTSFIGYVFKALQEWMPSYSKPTHTTKTLLSELITLVDTLKQETNDVPSESVVNTILSIADSCKTQTQKSKEAKTTIDSFLREHFVFDPNLHAQSAYTCADTNASTSADTNASTCADTNVDTCASTCADTNVDTCADTCASTCASTCASTCASTCADTNVDTCADTCVSTCASTCANTEYADLADPERIPLHIMQKTLNVPNELQADIDAITQTPQGYRAAAHILQNIELHQSIKHMLENPRAFKPILFNTKITRYLSQHIPPQDTFYKWNYYIEDNYEELRAATESIYPEKPDLEFAFIIYDVVDSSNQQKVDEFYYKYKDQIFSEVSSIQLGNWTLLGSFKANRERYNYFNQNNEIIKRILDRHEEDLKIGKEILRNTIYHKKAKNIQETGPDAPGLSIYNSTFHTDSGIKGLLSFKELKNLEKASGNIKKAREYDFIDDCEEKIKQLLSKENLTPDEESELIKTKKQLNNALEMLNVPDDTIRVDMWVNNNNKLEKEILYTKAEL
What is the function of this protein?
Plays an essential role in the assembly of the icosahedral capsid of the virus (By similarity).  Allows the assembly of 3 molecules of hexon protein p72 and formation of a thermostable trimer (By similarity).
What are the official names of this protein?
Protein B602L, pB602L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B602L family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PSBA_SORBI
Sequence: MTAILERRESTSLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAALEVPSLNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MED18_CAEBR
Sequence: MDNVVDVDEEGNQQKLSANSTPYQTQECVLYGSIFVKNVPDLERRLAGLWIRAAKNSMSTKCRSALEPPVHQILRRRFRTEHQIQNYWQLKYIGVPEPDQKCPTIVRKEISSLVHSQDMMTYAKSLGLRMDYEYITQGKLWTKGNIKILHSTLTRTLRAGTYDSSSLKSMSDSALVEISISLPESAEYMPAAKSLRDFADQLMPLVNMEKIDYWKKMFSTPAAPARR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUM16_ARATH
Sequence: MANNNSFSMSTMFNTIQEILNEEPLTVPSPPSRGGYSLFHIRKAEMDIQRIFNFMTGSEDLKDDISVLDTGTLMWMASLMTSDCDYFMVITTNKNGSKTLQKLMGMSDDMDVFFFEAIMRLFIHVMTDKYASYVTIQGMRVFQQDKRELMYDQILRYACFLAGDQYGCIALNEIITDLDDPYYRDQLLDIVANNALLLSNDAYGNFVVQHVLKLRDSRCTRNIADKLCGYCVELSFKKYGSYIVERLLEAGDVPMATVVLDLLACKTEMLIRLARSEYGNFVVCKALELTNEILTADLFYGLVNRLMPYRHLLHRSPRSKIATILDSMSVPN
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
What are the official names of this protein?
Putative pumilio homolog 16, APUM-16, AtPUM16.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_IDILO
Sequence: MIGLIQRVSRAKVTVADELVGSIGPGLLILLGVEHKDDEASAAKLAQRIANYRVFSDVEDKMNNSVIDAQGEVLVVSQFTLAADTRKGRRPSFSSAATPDQAQHLYQVFCEQMAAQGLPVKTGRFAADMQVELVNDGPVTFELKV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSX1_CARAU
Sequence: MTGREEAIDEKPKVKLYPSFGIDKARLNGSGFRSKGFAITDLLGLESDLQPHQSGSGAGANGEGQSAALGGFAFPGGSLPIGLGFLCSLAAQQPPGAPCFLPSHIPLLQPRTESHFMQNLEQQRDAYSDDDCLSGDRNDGKNSQKRKKRRHRTVFTSHQLEELEKAFHEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESIINSAKNGMMGSCAPWLLGEPAGMHKKSLEIGKNPPGTPESTHSDSYSEEHKVKDSDTTWSSGANGADDSEDMAIDLSSTSKQESKSTLKRSPPHTEDSSDSETES
What is the function of this protein?
May stabilize the differentiated state of a subset of cells in the inner nuclear layer and may be involved in cellular differentiation during retinal development and regeneration.
What are the official names of this protein?
Visual system homeobox 1, Homeobox protein VSX-1, Transcription factor VSX1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TBP_STRPU
Sequence: MYNPSQAVPVSLHKNQDNQDGGQQRSHYPQISSQQSQSYLSVPSIGTPSFGSVGSVSSLAPGSSFIPPSPMAPLTPATPASSESSGIVPQLQNIVSTVNLNCRLDLKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKREDNSRLAARKYARVVQKLGFAAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHGQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYDAFNNIYPILKSFKKTS
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TBP, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: END4_CHLMU
Sequence: MFVLPPPQEPLLGAHTSAAGGLHNALYEGRDIGATTIQLFTANQRQWKRRSLTQNMIEQFQTALDETSLSYIMSHAGYLNNPGAPNPEILEKTRICMYQEIADCIALGISFVNFHPGAALSDSKESCLDRAITSFSQMAPLFETNPPLVVLLETTAGQGSLIGSSFEELAYLIQGIKAHIPVGVCLDTCHIFAAGYDISSPEGWEQVLKHFDEVIGLSFLRAIHLNDSIFPLGKNKDRHAPIGEGCIGSESFCFLMRDERTRKLPKYLETPGGPDLWTKEIRYLQKVS
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: SUCC_PSEPG
Sequence: MNLHEYQGKQLFAEYGLPVSKGFAVDTPEAAAEACDKIGGSEWVVKAQVHAGGRGKAGGVKLVRSKEDAKAFAAQWLGKRLVTYQTDANGQPVTKILVESCTDIAKELYLGAVVDRSSRRIVFMASTEGGVDIEKVAHETPEKIIKATIDPLVGAQPFQGRELAFQLGLEGKQVAQFAKIFVGLAKLFKEHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKTFHDPSQDDPREAHAASFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDSNVAAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MNHC2_STAAR
Sequence: MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGTYGSNKSEPLITGGNQLFVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDAK
What are the official names of this protein?
Putative antiporter subunit mnhC2, Mrp complex subunit C2, Putative NADH-ubiquinone oxidoreductase subunit mnhC2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FIB_STAAS
Sequence: MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
What is the function of this protein?
Extracellular fibrinogen-binding protein that plays an important role in virulence.  By interacting with the alpha chain of fibrinogen and its derivative fibrin, enhances a non-functional interaction between fibrinogen and platelets and is responsible for repression of fibrinogen-dependent platelet aggregation.  In addition, assembles a fibrinogen protective shield around the bacteria which results in impaired phagocytic clearance by the host.  Mechanistically, interacts with host complement C3b deposited on the surface of the bacterium via its C-terminal and then recruits fibrinogen via its N-terminal.
What are the official names of this protein?
Fibrinogen-binding protein.
What are the subcellular locations of this protein?
Secreted.
Protein: MDTC_ESCF3
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NRDR_SYNWW
Sequence: MRCPYCQEFESRVVDSRSGDDGSFIRRRRECNACKRRFTTYERLEERGLLVIKKGGNREAFDRKKILDGIARACEKRPVSMEEMENMVASIERELRDLYEHEVSSKAIGEMVMDRLQRRDEVAYVRFASVYRQFTDLNSFIKTIDQLKQR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PG200_VACCW
Sequence: MTANFSTHVFSPQHCGCDRLTSIDDVRQCLTEYIYWSSYAYRNRQCAGQLYSTLLSFRDDAELVFIDIRELVKNMPWDDVKDCAEIIRCYIPDEQKTIREISAIIGLCAYAATYWGGEDHPTSNSLNALFVMLEMLNYVDYNIIFRRMN
What is the function of this protein?
Contributes to virulence by binding to the host IKBKB subunit of the IKK complex and preventing host NF-kappa-B activation in response to pro-inflammatory stimuli such as TNF-alpha or IL1B.  Mechanistically, sterically hinders the direct contact between the kinase domains of IKBKB in the IKK complex containing IKBKB, CHUK/IKKA and NEMO (PubMed:29748387).
What are the official names of this protein?
Protein OPG200.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG200 family.
Protein: SYF1_ASHGO
Sequence: MDEFVTAEDLVHEYSVLQEPDSVVNWSRYIAAKRDDPCSVSWVYERCLQALPAQWEVWREYLQFRMRLLDGVCAVQHAAEFEKVNRLFWRCVEHNAAVVEAWRLFLGHAQRQGALALVRQVVDAALRGVGLAKHRTVWEDVVAYIEELLPAEETDLGEEQDLHELVRGALFGGAGAEDAGADIWSSAMLRRYIQVAEDAEAVLALLQRTHDYATVVAVYEKHVLPVTRAKHKGRQSYESQFRYLVALDHTGATAKLEDAVARCAQLFPERAPSLTIFLAKHYVKQGNYNRCTDVLTDSLKHTAKSSEFASLYDFLVVFEESLIEVVLEHLQEHPENEERWGADLERHTDQLDGLLADHALLLNDLKLRQEPDNVKHWLDRVELFDKAASKASVYADAIASINYKSQTVPGQLGTLWWQYAQLYIDDGQYETAKTILDKALNVPYNFLQDPELIWTKWAEEELKRAGLDAAMQVLSHALQIPDDHELLRDKFESHEKMPAQTVIFSSLKLWSFYIDLLEASSESDEHLERTKAAYEATIQLKIATPLLFVNYAHYLQDKGNHVESFSIYERAVDIFPAETAFEIWDIYIGEALKYGLPKEQIRDLFESSLKMANEGVECKPFFLLYAKFERDNGMIETAANILHRACRAAQTMDAKRSLWTLCLNWCRQELGGSYARALYEECIQALPNHVAVVYVLEYAKVEEGLKQVKRARALLQYGARLLHPANNADLWEYWELFELRHGNKDTYKDMLQLKRKVEELLEGDGLPVPNQIGNIAFVASTDGLQNPGGESTNINNDELELDM
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle progression.
What are the official names of this protein?
Pre-mRNA-splicing factor SYF1.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NAGK_HAES1
Sequence: MYYGFDIGGTKIELAVFNEKLEKRYSERVDTPKHSYDEWLNVITHLVQKADEKFACKGTVGIGVPGFVNQETGIAEITNIRVADNKPILKDLSERLGREVRAENDANCFALSEAWDKDNQQYPVVLGLILGTGFGGGLVFNGKVHSGQSGMAGELGHLQLNYHALKLLGWDKAPIYECGCGNKACLDTYLSGRGFEMLYRDLQGKALSAKEIIRCFYDKDESAVKFVELFIELCAISIGNIITALDPHVIILGGGLSNFDYLYEALPKALPQHLMRTAKVPLIKKAKFGDSGGVRGAAALFLSRD
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: SLYX_CROS8
Sequence: MHNESTEHRIAELESRLAFQETTIEDLNAAITKHELELAKMREQLKIMVEKIKASQPSMIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: PEA15_MOUSE
Sequence: MAEYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNLSYIEHIFEISRRPDLLTMVVDYRTRVLKISEEEELDTKLTRIPSAKKYKDIIRQPSEEEIIKLAPPPKKA
What is the function of this protein?
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade.  Inhibits RPS6KA3 activities by retaining it in the cytoplasm.  Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis.  Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity).
What are the official names of this protein?
Astrocytic phosphoprotein PEA-15, 15 kDa phosphoprotein enriched in astrocytes.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with microtubules.
Protein: YO61_CAEEL
Sequence: MLPNGFSFLNPNLVAAANIQQVLLNQRFGMPPVGSIAQVPLLQMPTHSVVAPHVAAPTRPSPMLVPPGMGIDESHSSPSVESDWSVHTNEKGTPYYHNRVTKQTSWIKPDVLKTPLERSTSGQPQQGQWKEFMSDDGKPYYYNTLTKKTQWVKPDGEEITKGEQKPAAKAATVDTVALAAAVQQKKAESDLDKAMKATLASMPNVPLPSEKKEEESVNDEVELKKRQSERFRELLRDKYNDGKITTNCNWDQAVKWIQNDPRFRILNKVSEKKQLFNAWKVQRGKEERDEKRLAIKKSKEDLEKFLQEHPKMKESLKYQKASDIFSKEPLWIAVNDEDRKEIFRDCIDFVARRDKEKKEEDRKRDIAAFSHVLQSMEQITYKTTWAQAQRILYENPQFAERKDLHFMDKEDALTVFEDHIKQAEKEHDEEKEQEEKRLRRQQRKVREEYRLLLESLHKRGELTSMSLWTSLFPIISTDTRFELMLFQPGSSPLDLFKFFVEDLKEQYTEDRRLIKEILTEKGCQVIATTEYREFSDWVVSHEKGGKVDHGNMKLCYNSLIEKAESKAKDEEKESLRRKRRLESEFRNLLKEHNVDKDSEWTVIKPKIEKDKAYLAMENDDERETAFNHYKNGTSGTTAGSEILEKKKKKKDKKKKNKRSDNNSESEGEIREKEKKKKKKHSKEDRMDDEERGKKSKKSRKRSPSRSESPRHSSEKRKRRESEAD
What are the official names of this protein?
WW domain-containing protein ZK1098.1.