PharMolix/UniProtQA huggingface dataset:
Protein: TAZI_ASPTN
Sequence: MAYIQASSTQAVVVLLLVLVLTKIYRVYTGPLAHLPGPAISKWTGLVLQKHLFAGNRPRYVQKLHQLYGPIVRISPDELDVSDSAAAKSIHRVASRFYKGRFYEHIGHRSPKTLFSSTDPQFHAYRRRLLGGAMSETSIRQHEPTVAQKVKLCVDQMAREAERRGCIDVFKWWCFLATDTIGELSFGESFRMLEKGEKSQYSRDLELVSTLMIIRTTFPFLSRVAEYVPLPYFKQAAQSGKRMFGYASESIQRYKKHVEMKGXXXXXXXXXXXXXXXXXEGSLTEAEIRLEAGGYIVAGSDTSAISLTYLVWAVCKNPLIRDSLVAEVATLPEDFTDDDVRALPYTRRVIDETLRLYPAVPGALPRAVPPEGATLVDHFIPGGVTVSTQVYSLHRDPKIFPDPDRRFDPDRWIDPTTEMRDSFMPFGGGSRTCIGMHLARMELRLATAHFFRRFTSPTVSTKEGFTDDDMYQHMYFLVSPKGHRCLIDV
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of azaterrilone A and other azaphilones, a class of fungal metabolites characterized by a highly oxygenated pyrano-quinone bicyclic core and exhibiting a broad range of bioactivities (PubMed:35398258).  The first step of the pathway begins with the non-reducing polyketide synthase tazA that assembles one acetyl-CoA starter unit, five malonyl-CoA units, and catalyzes a series of Claisen condensations, methylation, PT-mediated cyclization, and finally releases the first hexaketide precursor through the R-domain.  The tazA product then undergoes reduction on its terminal ketone and the following pyran-ring formation by yet undetermined enzyme(s).  Dehydration and enoyl reduction, possibly involving the trans-enoyl reductase tazE leads to the next intermediate.  TazD is predicted as an acetyltransferase and might catalyze the acetylation steps leading to the synthesis of azaterrilone A.  Azaterrilone A is not the final product of the taz pathway and both the highly reducing polyketide synthase tazB and the dual enzyme tazHJ catalyze late steps of the pathway, leading to the production of the 2 final stereoisomers that contain additional polyketide modification whose structures have still to be determined (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase tazI, Azaphilone biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: MPRA_MYCA1
Sequence: MRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTKPEDDAESVAMTFSDLTLDPVTREVTRGQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGYVLRETPP
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity).
What are the official names of this protein?
Response regulator MprA, Mycobacterial persistence regulator A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTH_LACP3
Sequence: MASEDKKSKREHIIHFEDTASKSLDEVNGSVEVPHNAGFWKTLAAYTGPGILVAVGYMDPGNWITSIAGGASFKYSLLSVILISSLIAMLLQAMAARLGIVTGRDLAQMTRDHTSKAMGGFLWVITELAIMATDIAEIIGSAIALKLLFNMPLIVGIIITTADVLILLLLMRLGFRKIEAVVATLVLVILLVFAYEVILAQPNVPELLKGYLPHADIVTNKSMLYLSLGIVGATVMPHDLFLGSSISQTRKIDRTKHEEVKKAIKFSTIDSNLQLTMAFIVNSLLLILGAALFFGTSSSVGRFVDLFNALSNSQIVGAIASPMLSMLFAVALLASGQSSTITGTLAGQIIMEGFIHLKMPLWAQRLLTRLMSVTPVLIFAIYYHGNEAKIENLLTFSQVFLSIALPFAVIPLVLYTSDKKIMGEFANRAWVKWTAWFISGVLIILNLYLIAQTLGFVK
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LGR6_DANRE
Sequence: MLVVLLILHAVSCAHSHGSPGAAVPVKQCPSACQCEEDGILLLVDCSEQGLSSVPTDLSPLTSYLDLSMNNISEIQPNAFRNLHFLSELRLSGNHLRHIPGPMLQGLYNLKVLMLQNNQLERLPSEDPWELPNLLSLRLDANLIMEVPARTLSGMRSLRHLWLDDNALTEIPVSALNDLSSLQAMTLALNRITLIPDYAFRNLSNLVVLHLHNNMIRTLGQNCFEGLHSLETLELNFNDLQEFPVAIRTLAKLQELGFHNNNIKAIPERAFVGNPLLQTIHFYENPIQFVGRSAFQFLPKLHTLSLNGATEIREFPDLKGTTSLQVLTLTRAGLTSLPYDLCHLLPKLKVLELSHNVIEELPSFYHCTSLQEIGLQHNLIKQIEMNTFQQLGSLRSLDLSWNSINSIHPDAFFSLQSLIKLDLTGNRLSNLPMTGLTSLTHLKLKGNMALSRSFGLEDFPNIRVIEMPYAYQCCVFGGCSSYRSASQWEEQMGSEEEDFQKKSPSLFPIHTDNNYDLDLEEFQLAIEESKLQTSIQCTPIPGPFKPCDNLFDSWVVRLGMWLISLVSLMGNSLLILTVFTSPSYLSPVKFIIGTISGANLLTGLCTGTLALVDARTFGEFALHGAQWEMGAGCRAVGFLSVLASEGSILFLTLAAVQCSVSVSCARAYGKSPSLGSVRAAAVACLALSLAVAALPLIGVGEYGATPLCMPSPLPDGEPSTLGFMVALIMMNSLCFLVITGTYIKLYWDLMKGDFDSIWDCAMIKHVAWLIFTNCLLYCPVAFLTFSSLLSLFPVSEEVVKSVVLVLLPLPASINPLLYLLFNPHFREDMRLLLSRAHLNHDRNLDSFVSVDTEKSSYDSTQALVSFATEADGVFESLSVPNPETVARFTCPPSVALIPCQMQMKPSTDRENTGENLIRSAPGLIAKEQEHIRSSGVDTQNGTSIFSGAYHSTGPSAHSQVFT
What is the function of this protein?
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway.  Upon binding to R-spondins (rspo1, rspo2, rspo3 or rspo4), associates with phosphorylated lrp6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.  In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal (By similarity).
What are the official names of this protein?
Leucine-rich repeat-containing G-protein coupled receptor 6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMO_BURM1
Sequence: MSQSPKVGFVSLGCPKALVDSEQIITQLRAEGYEISGTYDGADLVVVNTCGFIDEAVQESLDAIGEALTENGKVIVTGCLGAKKSASGSGLIEEVHPKVLAVTGPHAVGEVMQAVHSHLPKPHDPFVDLVPPAGIKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPVAEVMLEAENLFKSGVKELLVISQDTSAYGVDVKYRTGFWNGKPIKTRMTDLVAALGELAAQYGAWVRLHYVYPYPSVDEVIPLMAEGPFKGHVLPYLDVPFQHAHPDVLKRMKRPANAEKVLERVQKWREICPDLTIRSTFIAGFPGETEAQFETLLDFIREAELDRVGCFAYSPVEGASANELDGALPDDVREERRARFMEVAEEVSARRIARKVGKTLKVLIDEVSDEGGIGRTAADAPEIDGVVYVEPATKASKRYKVGDFVSVKITGADGHDLWGEV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_SYNJB
Sequence: MRISLKWLRELVDFQLSPEELGEALTLAGFEVEEIEDRRTWADGVVLGRILAAEPHPNADKLQVCQVDLGSDRPATIVCGAANARPGILVAVATPGTHLPALSLTIAKADKRGVISEGMICSLAELGLEKSSEGIHEFPPDLDLEAHPLGSDVRPLLGLDDVVLDLTSTANRADALSMVGIAREVAALTRNPLRLPPVQPLQAKPIPNFQLRIADAKACPAYSGVLIEGVKVGPSPDWLKHRLAAAGMRSINNVVDITNLILLEWGQPLHAFDWDRLLQVMGKKKPTIEVRLAQPGETLKTLDGQTRTLQADSHLIVAGSQPVALAGVMGGEETEVGSTTTRIFLEAALFDPAVTRRSARSQGLRTEASTRYERGVNFATLDQARDRAVQLILELAGGAVAGLTTFDQRPPLERTLKLRLSRLIDVLGDEVQAADVEEILSALGFQLSRCEGANSQSALSPATETATVASCVWQVVVPPYRLRDIEREIDLIEEFARLYGYDRFSETLPTEPQVGSLSARETFTRQIREVLRGIGLTEVYHISLCPAEEDGSLVRIANPLSPEYSAVRNALLPGLVEAFRFNWDQGNGPLQAFEIGRVFAHALPPNPHPYREAEHIGGILGGDPNPHDWQHRNRPMDWFEAKGLLVSALERLGFGPEFRLDPPEEQSSLLHPGRQASLWIEGSRIGLFGQLHPRLCQEKGLPDQVYGFELQLDPLLESLERRGIVQFVPFSPFPAADRDIAFFAPLDLAVGEIEKVIRRAGGELLQSVQLFDEYRGQGVPAGQRSLAFRLVYRAPDRTLTDAEVEALQNQVRAQLATQFPVTLRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QTRT2_XENLA
Sequence: MKLSLSKVTSGARLGVISNFGRNGDKTLEVPGCLLYTKTASPPHLTHDTLQTIEGVPAVTHITLSTLAEHQEVLEEYKEGIGKFAGLPDAVFYCSTHDPVSPCPTGYNTNKAVSLWGSGGRIEMTTQKFISAQRVLRPDWFQCLSDGEVTPGGNSRKRIKKSVDRSLVFLDECLQLLSEHEELKPCVLIGAVEGGDLLDERLRSARETAKRPVGGFLLDGFHGISAGNEAKLSLVSAVTAELPEDKPRFIHGVGRPDEVLEFIQRGVDLFDSCFPYQVTERGCALIFTHCHRPDPETAVLEKSEMSDTERNGDVGAEIEEPDADQAEMTPFEICLKEKRFREDFGPLLEGCTCYCCRNHSRAYVHHLLMAKELLAGILLMIHNFQHYFSFFSSIRAALRDGEIKALAELIRKQNS
What is the function of this protein?
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Note=May associate with the mitochondrion outer membrane.
Protein: RHM3_ARATH
Sequence: MATYKPKNILITGAAGFIASHVANRLVRSYPDYKIVVLDKLDYCSNLKNLNPSKSSPNFKFVKGDIASADLVNYLLITEEIDTIMHFAAQTHVDNSFGNSFEFTKNNIYGTHVLLEACKVTGQIRRFIHVSTDEVYGETDEDASVGNHEASQLLPTNPYSATKAGAEMLVMAYGRSYGLPVITTRGNNVYGPNQFPEKLIPKFILLAMNGKPLPIHGDGSNVRSYLYCEDVAEAFEVVLHKGEVNHVYNIGTTRERRVIDVANDISKLFGIDPDSTIQYVENRPFNDQRYFLDDQKLKKLGWCERTNWEEGLRKTMEWYTENPEWWGDVSGALLPHPRMLMMPGDRHSDGSDEHKNADGNQTFTVVTPTKAGCSGDKRSLKFLIYGKTGWLGGLLGKLCEKQGIPYEYGKGRLEDRASLIADIRSIKPSHVFNAAGLTGRPNVDWCESHKTETIRVNVAGTLTLADVCRENDLLMMNFATGCIFEYDAAHPEGSGIGFKEEDKPNFTGSFYSKTKAMVEELLREFDNVCTLRVRMPISSDLNNPRNFITKISRYNKVVNIPNSMTILDELLPISIEMAKRNLRGIWNFTNPGVVSHNEILEMYKSYIEPDFKWSNFNLEEQAKVIVAPRSNNEMDGAKLSKEFPEMLSIKDSLIKYVFEPNKRT
What is the function of this protein?
Trifunctional enzyme involved in UDP-beta-L-rhamnose biosynthesis, a precursor of the primary cell wall components rhamnogalacturonan I (RG-I) and rhamnogalacturonan II (RG-II) (PubMed:17190829).  Catalyzes the dehydration of UDP-glucose to form UDP-4-dehydro-6-deoxy-D-glucose followed by the epimerization of the C3' and C5' positions of UDP-4-dehydro-6-deoxy-D-glucose to form UDP-4-keto-beta-L-rhamnose and the reduction of UDP-4-keto-beta-L-rhamnose to yield UDP-beta-L-rhamnose (By similarity).
What are the official names of this protein?
Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM3, Probable rhamnose biosynthetic enzyme 3, AtRHM3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the dTDP-4-dehydrorhamnose reductase family.
Protein: Y4379_ANADF
Sequence: MLHLLGQDSRALARKAGISLEDARRITGAVIGRGAPLRSARNVRRAVLDRVEALATPGELRRVACTDAKDGFRRYLLELGDGARVEAVRIPLFDTHHTVCLSSQAGCALGCSFCATGALGLARSLRAWEIVAQLLHVRADSTRPITGVVFMGQGEPFLNYDAVLEAAYTLCDPAGGRIDGRRISISTAGVVPMIRRYTAEGHKFRLCVSLNAAIPWKRRALMPIEEGFPLDELVDAVREHAAQRGRVTLEYVMIAGVNTGDEDAAALGRLLAGIPVRLNPIAVNDATGRHRPPDEAEWNAFRDALARELPGQPIVRRYSGGQDEHAACGMLSSRTR
What are the official names of this protein?
Probable RNA methyltransferase Anae109_4379.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFD_BUCAP
Sequence: MKLKKMNLPYISNTYDVRKIMFLVVLSCIPGLCTEIYFFGCGVLIQTLLFVIISLLFEIIILKMRRKNIKNSLFDYSSFLTAVLLGLSTPCALPWWMIIFSCFFAIVISKYLYGGLGQNIFNPAMIGYVVLLISFPVHMTAWNEKNSSLSFYNDIKKSINLILFYNKLNNSKKKICPDNFTEATPLDDFKTKSHFDYDFFPEESAVKKKTKIVSIAWKYINISFLIGGCFLLYKKVICWRIPLSFLSSLIFFSSITYFYSQKFFCSPLFHLFSGGTMMCAFFIATDPVTTSCTKIGKIFFGLIIGFLVWIIRNYSDYPDGIAFSVLFANMIVPLMDAYLKTSGYGHKNL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLMM_STRMK
Sequence: MGGRKYFGTDGIRGRVGQGVISADFVLRLGNALGRVLVAQRGQDGRRPIVVIGKDTRISGYMFEAALEAGLVAAGADVQLLGPMPTPAVAFLTRTLGVDAGIVISASHNPHYDNGIKFFSAQGEKLDDATELALEAALDVPFTTAESEKLGKASRAREAVGRYIEFCKASVPRAFDLRGVRLVLDCAHGATYQIAPLLFRELGAEVIGIGAEPNGVNINAGVGSTHIDNLAAKVRETRADLGIAFDGDGDRVLMADDQGNPVDGDDLLYILARAWKDEGRLRGPVVGTLMSNYGVEKAFADLQIPFVRSNVGDRYVHQALVEGGGVLGGEASGHLLCLDRATTGDGIVSALQVLVALRNGGQTLRQALKGLERVPQKTVNVRLGNVSAKATVQADSVQAALAAAQQSVAGRGRAFLRPSGTEPVVRVTVEADDATLMQETLDRLSAAVREAAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: API8_SOLTU
Sequence: MMKCLFLLCLCLLPIVVFSSTFTSQNLIDLPSESPLPKPVLDTNGKELNPDSSYRIISIGRGALGGDVYLGKSPNSDAPCPDGVFRYNSDVGPSGTPVRFIPLSGGIFEDQLLNIQFNIPTVKLCVSYTIWKVGNLNAYFRTMLLETGGTIGQADSSYFKIVKLSNFGYNLLYCPITPPFLCPFCRDDNFCAKVGVVIQNGKRRLALVNENPLDVLFQEV
What is the function of this protein?
Inhibitor of cathepsin D (aspartic protease) and trypsin (serine protease).  May protect the plant by inhibiting proteases of invading organisms.
What are the official names of this protein?
Aspartic protease inhibitor 8, API, API-8, PI-8, pi8, Cathepsin D inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Vacuole.
Protein: SARS_STAA8
Sequence: MKYNNHDKIRDFIIIEAYMFRFKKKVKPEVDMTIKEFILLTYLFHQQENTLPFKKIVSDLCYKQSDLVQHIKVLVKHSYISKVRSKIDERNTYISISEEQREKIAERVTLFDQIIKQFNLADQSESQMIPKDSKEFLNLMMYTMYFKNIIKKHLTLSFVEFTILAIITSQNKNIVLLKDLIETIHHKYPQTVRALNNLKKQGYLIKERSTEDERKILIHMDDAQQDHAEQLLAQVNQLLADKDHLHLVFE
What is the function of this protein?
Transcriptional regulator that controls expression of some virulence factors in a cell density-dependent manner.  Acts as an activator of the gene encoding protein A (spa).  Negatively regulates the expression of alpha-hemolysin (hla).
What are the official names of this protein?
HTH-type transcriptional regulator SarS, Staphylococcal accessory regulator S.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRX1_SCHPO
Sequence: MSSVESFVDSAVADNDVVVFAKSYCPYCHATEKVIADKKIKAQVYQIDLMNNGDEIQSYLLKKTGQRTVPNIFIHQKHVGGNSDFQALFKKGELDSLFNTA
What is the function of this protein?
The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase.  In addition, it is also involved in reducing some disulfides in a coupled system with glutathione reductase.  Thioltransferase catalyzes cellular thiol-disulfide transhydrogenation reactions.  It transfers reducing equivalents to cytosolic protein and nonprotein disulfides (By similarity).
What are the official names of this protein?
Glutaredoxin-1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
Protein: SMC3_ARATH
Sequence: MFIKQVIIEGFKSYKEQVATEEFSNKVNCVVGANGSGKSNFFHAIRFVLSDIYQNLRSEDRHALLHEGAGHQVVSAFVEIVFDNSDNRFPVDKEEIRLRRTVGLKKDDYFLDGKHITKGEVMNLLESAGFSRANPYYVVQQGKIASLTLMKDIERLDLLKEIGGTRVYEERRRESLRIMQETGNKRKQIIEVVHYLDERLRELDEEKEELRKYQQLDKQRKSLEYTIYDKELHDAREKLEQVEVARTKASEESTKMYDRVEKAQDDSKSLDESLKELTKELQTLYKEKETVEAQQTKALKKKTKLELDVKDFQDRITGNIQSKNDALEQLNTVEREMQDSLRELEAIKPLYESQVDKENQTSKRINELEKTLSILYQKQGRATQFSNKAARDKWLRKEIEDLKRVLDSNTVQEQKLQDEILRLNTDLTERDEHIKKHEVEIGELESRISKSHELFNTKKRERDEEQRKRKEKWGEESQLSSEIDKLKTELERAKKNLDHATPGDVRRGLNSIRRICADYRINGVFGPLVELVDCDEKFFTAVEVTAGNSLFNVVVENDDISTKIIRHLNSLKGGRVTFLPLNRIKAPRVNYPKDSDAIPLLKKLKFDSKFEPALGQVFGRTVVCRDLNVATRVAKNDDLDCITMEGDQVSRKGGMTGGFYDHRRSKLRFMNIIMQNTKSINEKEKELEDVRRQLQVIDQQITQLVTEQQRLEADWTLCKLQVEQLKQEIANANKQKHAIHKAIEYKEKLLGDIRTRIDQVRSSMSMKEAEMGTELVDHLTPEEREQLSKLNPEIKDLKEKKFAYQADRIERETRKAELEANIATNLKRRITELQATIASIDDDSLPSSAGTKEQELDDAKLSVNEAAKELKSVCDSIDEKTKQIKKIKDEKAKLKTLEDDCKGTLQDLDKKLEELFSLRNTLLAKQDEYTKKIRGLGPLSSDAFDTYKRKNIKELQKMLHRCSEQLQQFSHVNKKALDQYVNFTEQREELQNRQAELDAGDEKIKELITVLDQRKDESIERTFKGVAHHFRDVFSELVQDGYGNLIIMKKKDLDNDDEDDDDDDGGREAVTEGRVEKYIGVKVKVSFTGQGETQLMKQLSGGQKTVVALALIFAIQRCDPAPFYLFDEIDAALDPQYRTAVGNLIRRLADDYGTQFITTTFRPELVRVADKIYGVFHKNRVSIVNVISKDQALDFIEKDQSHDT
What is the function of this protein?
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle.  The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped.  At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.  Cohesion is coupled to DNA replication and is involved in DNA repair.  The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement (By similarity).  Essential protein plant viability.  Required for chromosome segregation (e. g.  sister chromatid alignment) and cell division during embryogenesis.
What are the official names of this protein?
Structural maintenance of chromosomes protein 3, SMC protein 3, SMC-3, Chromosome segregation protein SMC-3, Cohesin complex subunit SMC-3, Protein TITAN7.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus matrix. Chromosome. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere. Note=Primarily associated with the nuclear matrix during interphase and with chromatin from prophase through anaphase in both somatic and meiotic cells. During mitosis and meiosis the protein also colocalized with the spindle from metaphase to telophase.
Protein: OR5H2_HUMAN
Sequence: MSNEDMEQDNTTLLTEFVLTGLTYQPEWKMPLFLVFLVIYLITIVWNLGLIALIWNDPQLHIPMYFFLGSLAFVDAWISSTVTPKMLVNFLAKNRMISLSECMIQFFSFAFGGTTECFLLATMAYDRYVAICKPLLYPVIMNNSLCIRLLAFSFLGGFLHALIHEVLIFRLTFCNSNIIHHFYCDIIPLFMISCTDPSINFLMVFILSGSIQVFTIVTVLNSYTFALFTILKKKSVRGVRKAFSTCGAHLLSVSLYYGPLIFMYLRPASPQADDQDMIDSVFYTIIIPLLNPIIYSLRNKQVIDSFTKMVKRNV
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5H2, Olfactory receptor OR3-10.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: INV2_YEAST
Sequence: MLLQAFLFLLAGFAAKISASMTNETSDRPLVHFTPNKGWMNDPNGLWYDEKDAKWHLYFQYNPNDTVWGTPLFWGHATSDDLTNWEDQPIAIAPKRNDSGAFSGSMVVDYNNTSGFFNDTIDPRQRCVAIWTYNTPESEEQYISYSLDGGYTFTEYQKNPVLAANSTQFRDPKVFWYEPSQKWIMTAAKSQDYKIEIYSSDDLKSWKLESAFANEGFLGYQYECPGLIEVPTEQDPSKSYWVMFISINPGAPAGGSFNQYFVGSFNGTHFEAFDNQSRVVDFGKDYYALQTFFNTDPTYGSALGIAWASNWEYSAFVPTNPWRSSMSLVRKFSLNTEYQANPETELINLKAEPILNISNAGPWSRFATNTTLTKANSYNVDLSNSTGTLEFELVYAVNTTQTISKSVFADLSLWFKGLEDPEEYLRMGFEVSASSFFLDRGNSKVKFVKENPYFTNRMSVNNQPFKSENDLSYYKVYGLLDQNILELYFNDGDVVSTNTYFMTTGNALGSVNMTTGVDNLFYIDKFQVREVK
What are the official names of this protein?
Invertase 2, Beta-fructofuranosidase 2, Saccharase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
[Isoform Intracellular]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform Secreted]: Secreted.
Protein: FABH_STREM
Sequence: MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRHISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATNAFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDGAGGVLLEASEQQHFLAEALHTDGARSQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIFDFAIRDVSRSIAAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMHYGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_CHRSD
Sequence: MRKIAIIGAMAEEVERLASHLENRQTRQHAGSTFHSGHLHGVEVVILQSGIGKVNAAVGTTQLLEAYQPDAVINTGSAGGFGVDLDVGDVVISSEVRHHDVDAVVFGYEYGQVPQMPAAYAPDPHLVNVARECIEGLGELRVAEGLICTGDIFMADKAAVDQARERFPSMLAAEMEAAAIAQTCHLYGCPFVVIRALSDIAGKESDLSFQAFIEKAATHSAMMVEAMVKRLGTAS
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: MOAA_METM7
Sequence: MEDRYGREIRSFRLSITPKCNLKCFYCHKEGRNEEHGKLMSADEIGKIVKSSLEFGVRKIKISGGEPLLRTDLPEIIENIKDDQIKDISLTTNGILLEKYAQKLKDAGLDRVNVSLDTLDPEQYKQITAGGNIESVKKGIEKAIEVGLTPLKVNFLAMDCTINQLPAIMDYCRKIGAILQVIEFIPMEEELKHHHIDVVPIEEEIGKKADQVFTRKFMQNRKKYIVDGLEVEFVRPMDNTEFCGHCTRIRLTYDGYLKPCLLRDDNLVDVANPLRNGEDIRKYFIKCIEEREPFCKAQ
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: GLGC_ROSDO
Sequence: MNREEQRLAQQTMAFVLAGGRGSRLYELTDRRAKPAMYFGGKSRIIDFPLSNAVNSGIRRIGVATQYKAHSLIRHLQRGWSFFRAERNESLDILPASQQMNDENWYKGTADAVAQNKDIIEGYGPKYIIILAGDHIYKQDYAEMIRHHVESGADVTVGCIEVPRMEASGFGVMKVDTEDRILDFIEKPGDPPAMPGHPDQALASMGIYVFETEYLFKIMEECAAVPGYSHDFGGDIIPTIVRGGKAVAHPFSRSCVRTVNEEAPYWRDVGTVDAFWQANLDLTDFKPALDLYDTEWPIWTYSELTAPAKFIHNEEGRRGSAVSSMVSGGCIISGSSLERCLLFTGVRTHSFSQLNGVVSMPYAIINRNARLTNVVVDRGVVIPQGLVVGEDPALDAQRFRRTDSGVCLITQPMIDKLDM
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.