PharMolix/UniProtQA huggingface dataset:
Protein: MER3_EUPOC
Sequence: MKAIFIILAILMVTQAFKMTSKVNTKLQSQIQSKFQSKNKLASTFQTSSQLKYYCWEEPYTSSITGCSTSLACYEASDCSVTGNDQDKCNNVGQNMIDKFFELWGVCINDYETCLQYVDRAWIHYSDSEFCGCTNPEQESAFRDAMDCLQF
What is the function of this protein?
Mating ciliate pheromones (or gamones) are diffusible extracellular communication signals that distinguish different intraspecific classes of cells commonly referred to as 'mating types'.  They prepare the latter for conjugation by changing their cell surface properties.
What are the official names of this protein?
Mating pheromone 3.
What are the subcellular locations of this protein?
Secreted.
Protein: TTD14_DROME
Sequence: MATLLSNGQQSVMASTSNGQEQQRHQDEPEQQQQVEIRKSSSPKPGAMPSLKLNRMGSVSPKDKRVYKIVLTGGPCGGKTTGQSRLCTFFENLGWKVFRVPETATVLLSGGVKFSDLTEKEAYKFQENLIRTMVQIENTYFELGNSSNRNCLIICDRGVMDASAYISKDKWEKMMAGNNWNPVEMRDNRYNQILHLVSAANGAEDFYSTEDHACRSEGVDLARELDYKSAAAWVGHPYFDVIDNSTNFETKMNRMIESVCQKLGIDIGDRLQATSRKLKYLVALLPPDSEFPPFQDFDVVHHYLQSAGPKVQARLRKRGQKNHWSYIHTQRRPNVHGQARIEVKTQLTHRDYMNLLAQRDDAHFTIYKKRRCFLINNQYFQLDIYKEPGHPRCKGLVLLETYSSLTGDALKNCMPKFLNIVKEVTGDPDYSMFNLSLKEDWSTTKKFCRSATHGKQEEQSPVPAKQYHPYDENSD
What is the function of this protein?
GTP-binding protein which is required for the light-dependent internalization of the TRPL ion channel from the rhabdomere on the apical surface of photoreceptor cells to the cell body and for the recycling of TRPL back to the rhabdomere in the dark.  Binds to 3-phosphoinositide (PtdIns(3)P) and phosphatic acid and so may interact with membranes, particularly the early endosome membrane where PtdIns(3)P is predominantly localized.  Plays a role in preventing photoreceptor degeneration.
What are the official names of this protein?
TRPL translocation defect protein 14.
Protein: RL10_THEAC
Sequence: MKEVSQQKKELVNEITQRIKASRSVAIVDTAGIRTRQIQDIRGKNRGKINLKVIKKTLLFKALENLGDEKLSKLKENSGGQIALLTSDLEPTEIYKIIESTFQKTAPRGGEIAPEDIVIQPMTTGFPPGPMMTEFQKVGLQTGVEKGKIAIKKETVFVKKGETIPKDKAKILEMLEIKPLEVGLQLLGLYSEGVVYSKEVLSLTPERIANDMAAAFSQAKAIAKSSMFFVDEVLRDLLAEAKIKADALALAGQFITEDNVKDFLVRANVNAIILNNVLNKGSTQETPEEKKEEAKKEEKSPDESISEGLGALFQ
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RPGF1_HUMAN
Sequence: MDTDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKIPEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRSAASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVEFVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKNKLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQLEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSPDALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
What is the function of this protein?
Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH.  Transduces signals from CRK to activate RAS.  Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1 (PubMed:12432078).  Plays a role in the establishment of basal endothelial barrier function.  Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
What are the official names of this protein?
Rap guanine nucleotide exchange factor 1, CRK SH3-binding GNRP, Guanine nucleotide-releasing factor 2, Protein C3G.
What are the subcellular locations of this protein?
Early endosome.
Protein: EFNB1_HUMAN
Sequence: MARPGQRWLGKWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV
What is the function of this protein?
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development (PubMed:8070404, PubMed:7973638).  Binding to Eph receptors residing on adjacent cells leads to contact-dependent bidirectional signaling into neighboring cells (PubMed:8070404, PubMed:7973638).  Shows high affinity for the receptor tyrosine kinase EPHB1/ELK (PubMed:8070404, PubMed:7973638).  Can also bind EPHB2 and EPHB3 (PubMed:8070404).  Binds to, and induces collapse of, commissural axons/growth cones in vitro (By similarity).  May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
What are the official names of this protein?
Ephrin-B1, EFL-3, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2.
What is the protein family that this protein belongs to?
Belongs to the ephrin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft. Note=May recruit GRIP1 and GRIP2 to membrane raft domains. SUBCELLULAR LOCATION: [Ephrin-B1 C-terminal fragment]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Ephrin-B1 intracellular domain]: Nucleus. Note=Colocalizes with ZHX2 in the nucleus.
Protein: ADF3_ORYSJ
Sequence: MANATSGVAVSEECKARFQELRAGRAHRFVVFKIDDAMRQVVVDRVGPRDAGFDELTASLPADGCRYAVYDHDFTVSDATATAAAGEGGEAPRSKIFFVSWSPAAADVRSKMVYASSNEGFKKELDGVQIDLQATDPSELTLDVLKDHTS
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers (By similarity).
What are the official names of this protein?
Actin-depolymerizing factor 3, ADF-3, OsADF3.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
Protein: Y023_SIFVH
Sequence: MSTQIQIKKLIERCDFLTTSVYEKYDLRNIIRNDERFIIRQGDLIITNKFIQNPAIRGLRHVHLTHLAFRGSHIILPYQNYTAVFHNEHGLVIIPEKIEKLAFYTFENSID
What are the official names of this protein?
Uncharacterized protein 23.
Protein: RL362_PECAS
Sequence: MQVLSSLRSAKNRHKDCIVVRRRGRVYVICKSNPRFKAVQGGKKKKG
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: Y049_OSHVF
Sequence: MDNLQWKYDMAGIKSAREQGYRRKIVARDISVSTGAKQYAYLLPPMYNLFLKQVHEKRDKNLYEVIDEKSPVRLYFDCDSFDRDEGGYGLDLDCKTSLKLFHDLLKNFILFLNPNSTANMKAHITRCIRQDKPNKHSFHAIYPGIVFKNINELKMFVLSFAYHLFEDKNDMRLAFKKQGKNKTLGRAFFDLAVYTKDRCFRLPFQSKKGDSAKLIPLREITLEEIENNICQPEDFVRKPDNVDTSIGDLLSAAVMEKYTGVKLSTYVRAYQEGVIKEKIKTKCIEKRNGSKKIKITTPRLEIEWDQMKIPGVETVEIREDKDFLQYFDPVELRGGFYSLYIHLLKDICYFLPDEVLKQWMGHTNDKKANYLIKSNRKKGAEYAMTGGYALELLAKIYGRCNVRDLRDPIPKPTNSFRNTTRINVTPDRWRPIEVSDMKKFFIDSQVRDLKTNTYNDCGMITAMADVDYGEKIALSKKLKMDTKKKCQFITGQMGASKSTGVMDYMVFSMISSIIANAMVIVPRCSLAGQTVKKIYNTYKEMISDKDRMKKIKNKRKIVINPYFSQAFTIGGLQEIYDELTSEITTTDTCGTICVCVLNSISKVRSHVFDTIIMDEPVTCVDNFYIDSEKKQKIPVKNILEKKGNTIAVTDLMIDMLMKITRNANQLIFIDAAFTEDVIRLCETLYWGAYTMQGTVDDWRKVLENEGVDQSNIRHKIKRIKDENILIRKWIQNKKEWNYDKKTDTRTIISTTEIDHFRLFRPIEYICVYDKKITRPIYTHIIKYDCKQTMMNKLLDDVREGKKLVVYCSVGKETASIINTINSMTSRECIVLPKVGGVTAKSLKGKENQLDEYMRSMEVVVVSSVLGTGTSYPEEGLFDAAYMFCKVTYGTPQISDMIQLSARVRATTTRTLHYHITTSTSGHKPNGDALKNSDYHGISFKDHLDKTYTSRDHLHRVHMSRPSLASEFMRNELQQSFGHVIDETLEKKLPTHETNSEIEKEKHSDGKRKESKMAQEIDKHHPDVYTDVMATSNRNMTDEDGTKYQTIVRHCVVRTNNTTEPDRTMDVDWDSSQGTSGEIFHRPVTVDRSRITEQLVATPGPSTSRKRKLSDDDEYEKYDSGIEDIETDVDEEEEVQNKL
What are the official names of this protein?
Uncharacterized protein ORF49.
Protein: ENO_ECO24
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: KTHY_FRATF
Sequence: MQSKFIVIEGLDGAGKSTAISFVRKYLEKNNLAAIYTREPGGTKIAEELRNLVLHNKYDEEIHSDSELLMIYAGRVQHYRNLIAPALEKGINVVSDRFYWSSMAYQGGGRGVELSKIRALNDNFLNGCEPDLVIYLDIDPILGLQRAQKVGSPDRIEKAGLEFFNRTRKVFKDLVKDLDNAIEIDAAKSIQEVEKQIYLILDKHFNFQN
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ARCC_SYNY3
Sequence: MNSPNQNTRPIVIALGGNALLQRGQPPEAEIQKANIHIAALAIAKIARHYPVVVTHGNGPQVGLLALQGECEKSCKPYPLDVLGAETEGMIGYLLEQELRNQLPGRDVVTLLTQIVVDRQDPAFLQPTKPIGPVYTLEQAQQLAQERGWAIAADGQGYRRVVASPEPKRIIELPTIQLLVKSGALVVCAGGGGIPVVVNEAGGLQGVEAVIDKDLAAALLAQNLQAQGLLLLTDVDGVYENWSTNYAHCFEQTTPKNLRRYRFAAGSMGPKVEAACRFVETTGQWCGIGKLDQALDIIDGKAGTVVMP
What are the official names of this protein?
Carbamate kinase.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_DESHY
Sequence: MLQIKIVAVGKIRERFLMEGIKEYAKRLSAYIRLEMTEIADEPCPERLSAADEERVKDREGERLLKGIGPQEHVILLDLQGKEFTSPDFSEYMDDLALMGKSSVTFIIGGSLGVSGEVRKRADYRWSFSRLTFPHPLMRLMLLEQIYRAMRISKGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3262_YERE8
Sequence: MQQYCELVRRFYAQIASGDQGYVSDALGCVLKALDEVAANDALPSSVREQAAFAAANLLVSDYVDE
What are the official names of this protein?
UPF0253 protein YE3262.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: CPXT_SYNY3
Sequence: MSHSTDLSALARWMAADFSNQAQAFENPPFYAHIRVAIRPLDQAKFGDRLLFLEQAYDFMLQRPYRLRVLKLKVVEDHIEIENFKVKDEEKFYGAARDLGKLAQLTPADLEPMHGCDMIVEWTGTSFKGEVQPGRQCRVMRDGKETYLENSFEVSETGLISLDRGYDPETNERVWGSVAGAFHFVRWQSFADEVSF
What is the function of this protein?
Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.
What are the official names of this protein?
Chromophore lyase CpcT/CpeT.
What is the protein family that this protein belongs to?
Belongs to the CpcT/CpeT biliprotein lyase family.
Protein: GON1_ALLMI
Sequence: QHWSYGLQPG
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Gonadoliberin-1, Gonadoliberin I, Gonadotropin-releasing hormone I, GnRH-I, LH-RH I, Luliberin I.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLRT_CITMA
Sequence: MDTKHQDKPSILMLPWLAHGHIAPHLELAKKLSQKNFHIYFCSTPNNLQSFGRNVEKNFSSSIQLIELQLPNTFPELPSQNQTTKNLPPHLIYTLVGAFEDAKPAFCNILETLKPTLVMYDLFQPWAAEAAYQYDIAAILFLPLSAVACSFLLHNIVNPSLKYPFFESDYQDRESKNINYFLHLTANGTLNKDRFLKAFELSCKFVFIKTSREIESKYLDYFPSLMGNEIIPVGPLIQEPTFKEDDTKIMDWLSQKEPRSVVYASFGSEYFPSKDEIHEIASGLLLSEVNFIWAFRLHPDEKMTIEEALPQGFAEEIERNNKGMIVQGWVPQAKILRHGSIGGFLSHCGWGSVVEGMVFGVPIIGVPMAYEQPSNAKVVVDNGMGMVVPRDKINQRLGGEEVARVIKHVVLQEEAKQIRRKANEISESMKKIGDAEMSVVVEKLLQLVKKSE
What is the function of this protein?
Involved in the production of the bitter neohesperidosides in citrus.  Shows a strict specificity for UDP-rhamnose as donor.
What are the official names of this protein?
Flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase, 1,2 rhamnosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NDK_ACIF2
Sequence: MAVERTLSIIKPDAVQKNAIGAILGRFEKAGLRIAAAKMLHLSRDDAGGFYAVHQARPFYGELCDFMSSGPVLVTVLEGEGAIAKNRDLMGATNPKDAAAGTIRADFADSIDANAVHGSDSAETAAWEISYFFGQREIFAH
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y325_THEMA
Sequence: MNFQGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIFGDVAKDAEQIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLLSKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVNAVCPGTTQSEGLMARVKASPNPEELLKKMTSRIPMKRLGKEEEIAFAILFAACDEAGFMTGSIINIDGGSTAV
What are the official names of this protein?
Uncharacterized oxidoreductase TM_0325.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ATPA_CUCSA
Sequence: METIRADEISNIIRERIEQYTREVKIVNTGTVLQVGDGIARIYGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLLIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEISSSDSRLIESPAPGIILRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGQNVICVYVAIGQKASSVAQVVSTLQERGAMEYTIIVAETADSPATLQYLAPYTGAALAEYFMYRKQHTSIIYDDPSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSALGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQSAPLTVDEQIMTVYTGTNGYLDSLEIAQVRKFLVELRTYVKTNKPQFQEIISSTKTFTPEAEVLLKEAIQEQMERFLLQDQV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RL4_THEM4
Sequence: MAKVDLFNIKGENIGTVELKEEVFAIEPNQDVMWRYIDMQLTNSRAGTASTKTRGEVSGGGRKPWIQKHTGRARQGSIRAPHWRHGGVAHGPKPRVYFKRLNKKMKRLALKSALSLRLKENNLVVVDDIKFEKPRTKDLREVLKNLGLENQKVLIVLPKKESEYENVKISGRNIPGVKVLIADNPGVDRVNIDGLNVYDILNHDKLVLLQGTVQKIEEVLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: INP5E_PANTR
Sequence: MPSKAENLRPSEPAPQPPEGRTLQGQLPGAPLAQRAGSPPDVPGSESPALACSTPATPSGEDPPARAAPIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPSLLPPRPPPALSLDIASDSLRTANKVDSDLADYKLRAQPLLVRAHSSLGPGRPRSPLACDDCSLRSAKSSFSLLAPIRSKDVRSRSYLEGSLLASGALLGADELARYFPDRNVALFVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQEGCSDRREWETRLQETLGPHYVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTVQALALPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSDHRPVYGLFRVKVRPGRDNIPLAAGKFDRELYLLGIKRRISKEIQRQQALQSQNSSTICSVS
What is the function of this protein?
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3), phosphatidylinositol 4,5-bisphosphate(PtdIns(4,5)P2) and phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Specific for lipid substrates, inactive towards water soluble inositol phosphates (By similarity).  Plays an essential role in the primary cilium by controlling ciliary growth and phosphoinositide 3-kinase (PI3K) signaling and stability (By similarity).
What are the official names of this protein?
Phosphatidylinositol polyphosphate 5-phosphatase type IV, 72 kDa inositol polyphosphate 5-phosphatase, Inositol polyphosphate-5-phosphatase E, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol polyphosphate 5-phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle. Cytoplasm. Nucleus. Note=Peripheral membrane protein associated with Golgi stacks.
Protein: RF1_METMA
Sequence: MTEQSAHEKYEFKKKLEGLRDKKGRSTELISLYIPPDKQIFDVTNQLKDEHGQAANIKSKLTRTNVQGAIESLLSRLRYLDKVPENGIVYFTGAVDIGANKTSMESEVIVPPDPITVYKYHCDSSFYLEPLEDMLKDKNTYGLLVLDRREATIGLLVGKRIQPFRNLTSTVPGKQRKGGQSAHRFQQLRLIAIHDFYKRIGDAASEVFMAVDHKDLKGVLIGGPSPTKEEFHAGEFLHHELMKKILGLFDTAYTDESGLSELVNAAGEKLQDLELMGQKNAVRDFFKELIADSGKVAYGESQVRANLEINSVDVLLLSEDLRAERVTTKCSVCGYENKWTRRWKPGEPAPAAGNCPKCGSSLEVTDVTDIVDEFSELADKSNAKVVFVSTDFDEGSQLMNAFGGIAAILRYNTGV
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_CARHZ
Sequence: MTKLNGTGLLKGLAITFKELWKKPVTLEYPEHKEKLPPRFHGSFTLHSEKCIACGLCQQACPNKVIKVGSIKDENNKRKLASYEMEMKYCLFCGLCVEACPTNALVFNQEYELAKYRIEDIKLTLFKREEITTGEGSENA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YL87_CAEEL
Sequence: MTGSTASPPEPSAPPADSPFAPVTQNDSSPTSDSTETMSRIPTGIKVPDVVANIDTAQVAAKVESFKKWTIGTFKNSKQQLLEHMGKIDKTVDPEFEAQCEVLKDIHRRYGLVVAAAKNFSHVLTQMAEAEKKLSESFYQLSMKEEQIKAQCTMTSETMRGVGEQAASLDACLRYFISSMETVYNQTITDTLHTIYNTESARIEYDVDRNDISAATNPPQGQLTKNLPVGATEKCEEKKAKYEKLKNDAKIKMRLLEENRISVVAAQLEKLQSALAAYYSGNAKLLEASVRELSFLQSPQPSFIPTM
What are the official names of this protein?
Uncharacterized protein F54C8.7.
Protein: GLND_PSEP1
Sequence: MPQVDPELFDRGQFQAELALKASPIAAFKKAIRLAGEVLDKRFSAGSDIRPLIEARAWLVDNILQQAWNQFDWGDQSGIALVAVGGYGRGELHPHSDIDLLILLGAAEHEQYRDAIERFLTLLWDIGLEVGQSVRTVDECAEQARADLTVITNLMESRTIAGPEALRQRMLEVTSTAHMWPSKEFFLAKRAELKARHHKYNDTEYNLEPNVKGSPGGLRDIQTVLWVARRQYGTLNLHALAGEGFLLESENELLASSQDFLWKVRYALHMLAGRAEDRLLFDHQRSIATLLGYSDENPKRAIEQFMQQYYRVVMSISQLCDLIIQHFEEVILADEESGSTQPLNARFRLHDGYIEAAHPNVFKRTPFAMLEIFVLMAQHPEIKGVRADTVRLLREHRHLIDDTFRTDIRNTSLFIELFKCEIGIHRNLRRMNRYGILGRYLPEFGLIVGQMQHDLFHIYTVDAHTLNLIKHLRKLQYTPVSEKFPLASKLMGRLPKPELIYLAGLYHDIGKGRQGDHSEIGAVDAQKFCERHQLPAWDSRLIVWLVQNHLVMSTTAQRKDLSDPQVINDFALHVGDETRLDYLYVLTVADINATNPSLWNSWRASLLRQLYTETKRALRRGLENPLDREEQIRQTQSSALDILVREGTDPDDVEQLWAQLGDDYFLKHTAADVAWHTDAILQQPADGGPLVLIKETTQREFEGGTQIFIYAPDQHDFFAVTVAAMSQLNLNIHDARIITSSSQFTLDTYIVLDNDGGSIGDNPQRVKQIRDGLTEALRNPEDYPTIIQRRVPRQLKHFDFPPQVTILNDAQRPVTILEITAPDRPGLLARLGRIFLEFDLSLQNAKIATLGERVEDVFFITDADNQPLSDPQLCSRLQEAIVQQLQAGQGSDTSQTRVTF
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: ISPT_STRP6
Sequence: MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVAFFDKYVPVLHENNVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQDVLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFYFTPVLWPDFKKAELLKAIADYNRRQRRFGKV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: CAIA_SALSV
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQVLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.