PharMolix/UniProtQA huggingface dataset:
Protein: 5HTR_BOMMO
Sequence: MEGAEGQEELDWEALYLRLPLQNCSWNSTGWEPNWNVTVVPNTTWWQASAPFDTPAALVRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLVMPLGAVYEVVQRWTLGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTNIDYIHASTAKRVGMMIACVWTVSFFVCIAQLLGWKDPDWNQRVSEDLRCVVSQDVGYQIFATASSFYVPVLIILILYWRIYQTARKRIRRRRGATARGGVGPPPVPAGGALVAGGGSGGIAAAVVAVIGRPLPTISETTTTGFTNVSSNNTSPEKQSCANGLEADPPTTGYGAVAAAYYPSLVRRKPKEAADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPTCDCEVSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRVRRRRAPQ
What is the function of this protein?
This is a receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter, a hormone, and a mitogen.
What are the official names of this protein?
5-hydroxytryptamine receptor, 5-HT receptor, Serotonin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YNFA_ECO45
Sequence: MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLALFVWLLTLHPAASGRVYAAYGGVYVCTALIWLRVVDGVKLTLYDWTGALIALCGMLIIVAGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL23_BURL3
Sequence: MSEIRKNDHRLMQVLLAPVISEKATLVADKNEQVVFEVAPDATKQEVKAAVELLFKVEVDSVNVLVQKGKQKRFGRSMGRRKDVKKAYVCLKPGQEINFEAEAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: YICR_ECOSM
Sequence: MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAIKINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
What are the official names of this protein?
UPF0758 protein YicR.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: RS14Z_MYCGE
Sequence: MAKKSLKVKQSRPNKFSVRDYTRCLRCGRARAVLSHFGVCRLCFRELAYAGAIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: FABA_PHOPR
Sequence: MKRQQSFEYDELVACGKGELYGPAFPSLPSDNMLMIDRVIEISSEGGEHGKGFIHAELDINPDLWFFDCHFKGDPVMPGCLGLDAMWQLVGFFLGWQGGEGKGRALGVGEVKFTGQILPTAKKVTYDIQLKRVINRKLVMGVADGRVLVDGKEIYVAKDLKVGLFTDTTNF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACA_STREM
Sequence: MAIILGADAHGNELKEVLKSFLQQEGFDVTDVTDIDKDFIDNTLAVAQAVNDKDTNLGIMVDAYGAGPFMVATKLKGMIAAEVSDERSAYMTRGHNNARMITLGARIVGEELAKNIAKAFVVGSYDGGRHQIRVDMLNKMA
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: NADK_ECOSM
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCAKGYEVIVEQQIAHELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 2AB2D_ARATH
Sequence: MESITLDIELLQLPETSPMSMKSNQDFVKKLFDQWLALPETNRLVTSLVNDAKAGVALNVMCGGGSSGTNSGSNSPLASMFPARNGPPLSPRNSTGSPRIARQRTGLSNLSSPLKVVSDHVKELIPQFYFEDGRPPPNDLKEQCIAKINSLFYGHEDGLQLQEFKLVTTEICKVPSFFSTSIFKKVDTNNTGFVKREDFIDYWVKGNMLTKEITSQVFTILKQPDHNYLVQDDFKPVLQELLATHPGLEFLQGTPEFQDRYAETVIYRIYYYINRSGNGHLTLRELKRGNLVDAMQHADEEEDINKVLRYFSYEHFYVIYCKFWELDTDHDFLIDKENLIRYSNHALTYRIVDRIFSQVPRKFTSKTEGKMGYEDFVYFILAEEDKSSEPSLEYWFKCIDLDANGVLTRNELQFFYEEQLHRMECMAQEAVLFEDILCQLFDMVKPEDEGFICLNDLKGSKLSGNVFNILFNLNKFMAFETRDPFLIRQERANPTWTEWDRFAHREYIRLSMEEDVEDASNGSAEAWDDSLEVPF
What is the function of this protein?
Probable regulatory subunit of type 2A protein phosphatase.
What are the official names of this protein?
Probable serine/threonine protein phosphatase 2A regulatory subunit B''delta, AtB''delta.
Protein: MEIG1_MOUSE
Sequence: MATSDVKPKSISRAKKWSEEIENLYRFQQAGYRDEIEYKQVKQVAMVDRWPETGYVKKLQRRDNTFFYYNKERECEDKEVHKVKVYVY
What is the function of this protein?
Essential for spermiogenesis.
What are the official names of this protein?
Meiosis-expressed gene 1 protein, Protein expressed in male leptotene and zygotene spermatocytes 278, MLZ-278.
What is the protein family that this protein belongs to?
Belongs to the MEIG1 family.
Protein: VPP1_HUMAN
Sequence: MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEEMDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKRNFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPSEMGRGTPLRLGFVAGVINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLNIFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLFKPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEPSEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that transports protons across cellular membranes.  V-ATPase is responsible for the acidification of various organelles, such as lysosomes, endosomes, the trans-Golgi network, and secretory granules, including synaptic vesicles (PubMed:33065002, PubMed:34909687, PubMed:33833240).  In certain cell types, can be exported to the plasma membrane, where it is involved in the acidification of the extracellular environment (By similarity).  Required for assembly and activity of the vacuolar ATPase (By similarity).  Through its action on compartment acidification, plays an essential role in neuronal development in terms of integrity and connectivity of neurons (PubMed:33833240).
What are the official names of this protein?
V-type proton ATPase 116 kDa subunit a 1, V-ATPase 116 kDa subunit a 1, Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit, Vacuolar adenosine triphosphatase subunit Ac116, Vacuolar proton pump subunit 1, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: SYC_ORITI
Sequence: MNLYIYNTLSRKKERFVPLNCKSVKMYVCGPTVYDIPHIGNARSVVVYDLLYRVLSLLYGRQNITYVRNITDIDDKIINRAKELKISIFKLTHETTIKFHEDMSYLGCCNPTIEPKATDNIDVMINIITSLIQTGNAYSTDDGHVYFAVKTFQDYNLLSRRTFDSMILNSRESSEPQKSYFADFVLWKPANADNEDIDAVFDSPWGKGRPGWHIECSAMSYKFLGENFDIHGGGADLIFPHHTNEIAQSRCAFPESRHALYWVHNGFLTVKGEKMSKSLNNFVTVRDLQKQNINGAAVRLMFLSTHYRKPLDFNDKSLNDAKNIINYLYDTIDSVNGTAQQQDNIKAEFKGNAFTVEFISALLDDLNSPKAIACLLNIAKQIRRQNQSEDKLALTQALLYASNLLGILHNYQFIKDSNDVKDNSNVTPHEIDLLIAKRIQAKQDKDWNLADQIRSQLLSNGISLTDKADGTTSWKVIK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MICLS
Sequence: MTIIRKKHPLIKIINHSFIDLPAPSNISSWWNFGSLLGLCLAIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGVYYGSYNMIETWNMGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDLLGVLVLLMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPLLHTSKQRALTFRPITQTMYWILVADLLVLTWIGGQPVEYPFIIIGQTASITYFAIIMILMPIAGMIENNILDLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYT_PROM5
Sequence: MPKITLPDGTKKVFEKAVTTLDIAKSIGAGLAKATIAGKVNNVLFDATLPIKNDSKVVIITSRDKEGIEIIRHSFAHLIGHAVKQIYPNIKMAIGPVIEDGFYYDIFSEYRFTPEDLIKIEERINQLIRKDYDVEVLQVSKQEAIKTFKERDEIFKLRIIEEIDEKDSINLYKHEEYIDMCRGPHVPNTRHLRHFKLLKLSGSYWRGDSKNESLQRIYGTAWSKEKDLTNYLKRIEEAEKRDHRKLGKKHSLFHIQEESPGMIFWHPNGWIIYQILEKYIREILRKNEYLEIKTPQAVDKSLWEKSGHWEKFRDDMFTTASENRTYAIKPMNCPCHIQVFNQGLKSYKDLPLRLAEFGSCHRNEPSGALHGLMRVRNFTQDDAHIFCTEEQIQEEVSTFIDLVFEVYNTFGFDEIIIKLSTRPEKRVGSEDIWDKSEEALTEALNNKNLKWELQPGEGAFYGPKIEFSLKDCLNRIWQCGTIQVDFSMPVRLDATFVDINNEKKSPVMLHRAILGSFERFIGILIEQYEAKFPIWLAPTQIILLSITERNIKKCIEFNNLLNTKGYRSKIDIRNEKIGYKIRESTLARIPLIGIVGDKEQELNSVTLRALDGSNLGIYELDNLFKLMNTLIEKKGRVD
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_CLOK5
Sequence: MKILEVNCGSSSLKYQLIDMEDEKVLAKGLVERIGIDGSILTHKVNGEKHVVSEPIKDHRVAVKLVLEALVDKQHGVIKDMSEISAVGHRVVHGGEQYSDAVIIDDKVMESLKDCSKLAPLHNPPNIIGINACKAIMPNTPMVAVFDTAFHHTMPKYAYIYPLPYELYERYGIRKYGFHGTSHRFVSEEAARLMGKDISELKIITCHLGNGASICAVDRGKSIDTNMGFTPLAGLAMGTRCGDIDPAIIPFLTNEIGMSIDEISNIMNNKSGILGMSGISSDFRDVEEIASFKHDRRAQLALDVFYYRVKSFIGSYVAVLDGVDAIVFTAGVGENSSIGRAEICSGLTYLGITIDEEKNNIRGKATEITTANSKTKVFVIPTNEELVIARDTKFLVQKKISHKSK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCKN_CANLF
Sequence: AVQKVDGEPRAHLGALLARYIQQARKAPSGRMSVIKNLQNLDPSHRISDRDYMGWMDF
What is the function of this protein?
This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut.  Its function in the brain is not clear.  Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.  cholecystokinin 58 and cholecystokinin 8, but not cholecystokinin 58 desnonopeptide, stimulate amylase release from the pancreas.  cholecystokinin 58, but not cholecystokinin 8, increases bile-pancreatic volume.
What are the official names of this protein?
Cholecystokinins, CCK.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DMP1_HUMAN
Sequence: MKISILLMFLWGLSCALPVTRYQNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDNDCQDGY
What is the function of this protein?
May have a dual function during osteoblast differentiation.  In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin.  During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite.
What are the official names of this protein?
Dentin matrix acidic phosphoprotein 1, DMP-1, Dentin matrix protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Secreted, extracellular space, extracellular matrix. Note=In proliferating preosteoblasts it is nuclear, during early maturation stage is cytoplasmic and in mature osteoblast localizes in the mineralized matrix. Export from the nucleus of differentiating osteoblast is triggered by the release of calcium from intracellular stores followed by a massive influx of this pool of calcium into the nucleus.
Protein: YIDD_FRATH
Sequence: MFFKKITLIPFVMLINLYRYCISPFIPARCRYYPTCSEYALEALKTHGILKGLYLTTRRLLRCHPLSKRDYYDLVPCKNKKG
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y3610_DICDI
Sequence: MVNIFLIIVAVVIPALVALGSLYLIAYFQHPDDKNVAYFPKIIVILGITLAATSILMLPLDVANQGGKGGFPMDILWIVIYIVVAVFAIVICPFAMFFYESEEADPAAGSQIAGAFKGTFAILFAFAALTIVLYVFFGVAEIPTIVILSRFQIINYPIATDSINITTTLPEIASIVGGGNDKIKLDPGNPELLGNGSEYVEYRLDKEFLQFRVSIALFIITMVAFFGWLLFIIFGGIGLVALPFDMITDFKNRPQRIPYDKYLERKKKIGERATELVDVGKTIQSRTTGGIMSKRDRRNYNRFRQAIFLLEEDYERLKISYKRQGGKVILYYAQFFGGFIALGVSLGWLLHIIIYMITAPEPFHPFLNSLVISLNNAWGFLGVIVYGLLSFYLLFCVVKGNFKFGLRLFFLFPIHPMRVGNTMMNAFLFNVGLILITSVSITHFCTMAFSQFTSTTSINSLFETAVKNLKILKWFWVVYIFAIFAMSILTAIFLFIKPKDKPARIRV
What are the official names of this protein?
LIMR family protein DDB_G0293610.
What is the protein family that this protein belongs to?
Belongs to the LIMR family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: E1229_IXORI
Sequence: MEVRTFAFLQIVVFVALGIQLFAAVTDAADADDEFFTVDYCGMNCTLQQDGSWTPCTQKNAECKCYHESGSSVGLCLSTAYTDFNQFGDPNNSDLDAATPRHPDASSR
What is the function of this protein?
Salivary chemokine-binding protein which binds to host chemokines CXCL1 and CXCL8.
What are the official names of this protein?
Evasin P1229.
What are the subcellular locations of this protein?
Secreted.
Protein: TYSY_ARTS2
Sequence: MSIPTPYEDLLRDVLANGTHKSDRTGTGTLSVFGRQMRFDLSQSFPLITTKRVHFKSVAVELLWFLRGETNVKWMQDQGVTIWNEWADADGELGPVYGVQWRSWPTPDGGHIDQIAELVENLKSNPDSRRHIVSAWNVAELQDMALPPCHAFFQFYVADGKLSCQLYQRSADTFLGVPFNIASYALLTCMLAQQVGLEPGEFVWTGGDVHIYDNHMDQVLKQLKREPYEYPQLKILRKPDSIFDYTLDDFEVVGYQHHPTIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB1_VIBPA
Sequence: MAKLNAYFGEYGGQYVPQILVPALKQLEQAFIDAQEDPEFRSEFMTLLQEYAGRPTALTLTRNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKHEIIAETGAGQHGVATALACALLGLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVHSGSATLKDACNEALRDWSGSYEDAHYLLGTAAGPHPFPTIVREFQRMIGEETKNQILAREGRLPDAVIACVGGGSNAIGMFADFIEEESVRLIGVEPAGKGIDTDQHGAPLKHGKTGIFFGMKAPLMQDENGQVEESYSVSAGLDFPSVGPQHAHLNAIGRAEYDNVTDDEALEAFQELARSEGIIPALESSHALAHALRMARENPEKEQLLVVNLSGRGDKDIFTVHAILEEKGVI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 1.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: C71A4_SOLME
Sequence: MDVPCLWYSLLILLLLFIFLLIHHCFTTSKTQNMFLPPSPRKLPIIGNLHQLGSHPHRSLRKLSQKYGPVMLLHLGSKPVIVASSVDAARDILKTHDHVWATRPKYSIADSLLYGSKDVGFSPFGEYWWQVRSIVVLHLLSNKRVQSYRDVREEETANMIEKIRQGCDASVINLGEHLCFLTNNITSRVALGRTYDERESGIDAKDILEQFLQLLDTFNVGDYIPWLKWVNKITGLDTKVEKIAKKLDTFLDSVIEEHIIRNKKEEYAITDEAKDFVDVLLEIQNGKETDFPLQRDSLKAILLDAFAAGTDTIYTNLDWTMADVLRQPRAMKTLQNEVRGLAQGKSEITEDDLKNMQYLRAVIKESLRLHPPNSLLVPRESMEDVKLLGYYHIPARTQALINVWAIGRDPLSWENPEEFCPERFLNNDIDMKGLKFELLPFGSGRRGCPGSSFAIAVIELALARLVHKFNFALPKGTKPEDLDMTECTGIATRRKSPLPVVATPFSG
What is the function of this protein?
May have a role in maturation, such as during flavor formation or other metabolite production specific to aging tissues.
What are the official names of this protein?
Cytochrome P450 71A4, CYPLXXIA4, Cytochrome P-450EG2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y4276_NOSS1
Sequence: MAGHSKWANIKRQKAVVDAKKGKTFTQLSRAIILAARSGVPDPSGNFQLRTAIDKAKAAGIPNDNIERAIAKGAGTFGGDNASLEEIRYEGYGPGGVAILIEALTDNRNRTAADLRVAFSKNGGNLGETGCVSWMFDQKGVCVVSGVVDEDQLLEASLEGGAESYEMTEDETAEVFTEVANLEILNQTLKDQGFKVTDAELRWIPSNHLEVTEPDQARSLLKLIDTLEGLDDVQNVTSNFEMSENLMAVSFA
What are the official names of this protein?
Probable transcriptional regulatory protein all4276.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR35_RAT
Sequence: MFFYLSKKIAVPNNVKLKCISWNKDQGFIACGGEDGLLKVLRLETQTDDSKLRGLAAPSNLSMNQNLEGHSGAVQVVTWNEQYQKLTTSDQNGLIIVWMLYKGSWYEEMINNRNKSVVRSMSWNADGQKICIVYEDGAVIVGSVDGNRIWGKDLKGIQLCHVTWSADSKILLFGMANGEIHIYDNQGNFIMKMKLNCLVNVTGAISIAGIHWYHGTEGYVEPDCPCLAICFDNGRCQIMRHENDQNPVLIDTGMYVVGIQWNHIGSVLAVAGSQKVVTQDKDVNIVQFYTPFGEHLGTLKVPGKQMCSLSWEGGGLKIALAVDSFIYFANIRPDYKWGYCSNTVVYAYTRPDRPEYCVVFWDTKNNEKYVKYVKSLISITTCGDFCILATKADENHPQFVLVLCNSIGTPLDPKYIDLVPLFVAMTKTHVIAASKEALYTWQYRVAKKLTALEINQITRSRKEGRERIYHVDDVPSGSVDGVFDYSKAIQGTRDPICAITASDKTLIVGRESGVIQRYSFPNVALIQKYSLDCRACQLSLNCNSSRLAIIDIAGVLTFFDLDTRVTDSTGQQVVGELLKLERKDVWDMKWAKDNPDLFAMMEKTRMYVFRNLDPEEPIQTSGYICNFEDLEIKSVLLDEILKNPEHPSKDYIMNFEIRSLRDSRALIEKVGIEDASQFIEDNPHPRLWRLLAEAALQKLDLYTAQQAFVRCKDYQGIKFVKRLGNLQSESMKQAEVIAYFGRFEEAERMYLDMDRRDLAIGLRLKLGDWFRVLQLLKTGSGDADDSLLEQAHNAIGDYFADRQKWMNAVQYYVKGRNQERLAECYYMLEDYEGLENLANSLPENHKLLPEIAQMFVRVGMCEQAVSAFLKCNQPKAAVDTCVHLNQWNKAVELAKSHSMKEIGSLLARYASHLLEKNKTLDAIELYRKASYFFDAAKLMYKIADEEAKKRTKPLRVKKLYVLSALLIEQYHEQMKNAQRGKVKGKNSEATSALAGLLEEEVLSTTSRFTDNAWRGAEAYHFFILAQRQLYEGYVDTALKTALHLRDYEDIIPSVEIYSLLALCACASRAFGTCSKAFIKLESLETLSAEQKQQYEDLALEIFTKHTPKDNRKSELNSLLEGGEGKLPTCIATGSPIIEYQFWVCKVCKHYVLAQEISNYNFCPLCHSSVE
What is the function of this protein?
As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking (By similarity).  May promote CASP3 activation and TNF-stimulated apoptosis (PubMed:20193664).
What are the official names of this protein?
WD repeat-containing protein 35, Naofen.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
Protein: DGTL1_SHESW
Sequence: MTSSVWQERRHGEDKQRRFDHRSPYQRDRARILHSAAFRRLQAKTQVLGVGMNDFYRTRLTHSLEVSQIGTGIAAQLRRKYPQHKQLLCSMSLLESLCLAHDIGHPPFGHGGEVALNYMMRDHGGFEGNGQTFRILSKLEPYTLDFGMNLCRRTMLGILKYPAPYSKLFVAGEHNEITNHRQLKPSQWPPVKGIFDDDNDIFAWVLEPLSEADRSRFTSTQEGSHPALHHYPHLRTQFKSFDCSIMELADDIAYAVHDLEDAIVMGIVTASQWHQDVAPTLTNSSDAWIKQELADIGNKLFSHEHHLRKDAIGTLVNGFVTAIVISEDDVFEEPLLRFNATLEPEFAIALNVLKQLVYKYVIRKPEIQMLEYKGQQIVMGLFEAFASDPERLLPLNTQVRWRESEQQGLNTHRILADYISGMTDEFAGRLYQQLFSPKAGSNVELSKEM
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: GPDA_BACHK
Sequence: MTKITVVGAGSWGTALAMVLADNGHDVRIWGNRSELMDEINTKHENSRYLPGITLPSTIVAYSSLEEALVDVNVVLLVVPTKAYREVLQDMKKYVAGPTTWIHASKGIEPGTSKRISEVIEEEIPEDLIKDVVVLSGPSHAEEVGLRQATTVTSAAKRMEAAEEVQDLFMNSYFRVYTNPDIVGVELGGALKNIIALAAGITDGLGLGDNAKAALMTRGLTEIARLGRKMGGNPLTFAGLTGMGDLIVTCTSVHSRNWRAGNMLGKGHSLEEVLESMGMVVEGVRTTKAAHELAEKMEVEMPITAALYDVLFNGNNVKDAVGSLMGRVRKHEVEAIPDLL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 36019_ASFP4
Sequence: MPSTLQVLAKKVLALEHKENDHISREYYYHILKCCGLWWHEAPIILCFNGSKQMMIKTPIFEEGILLNTALMKAVQDNNYELIKLFTEWGANINYGLISINTEYTRDLCRKLGAKERLERHEVIQIMFKILDDTTSSNMILCHELFTNNPLLENVNMGQMRMIIHWRMKNLTDLLLNNNSISEILTKFWYGIAVKYNLKDAIQYFYQRFINFNEWRVTCALSFNNVNDLHKMYITERVHMNNDEMMNLACSIQDKNFSTIYYCFLLGANINQAMFISVLNYNIFNIFFCIDLGADAFKEGKALAKQKGYNEIVEILSLDIIYSPNTDFSSKIKPEHISFLLKNFYPKNLYIFDRCKPGLYYP
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-19R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.