PharMolix/UniProtQA huggingface dataset:
Protein: VNB_INBLE
Sequence: MNNATFNCTNINPITHIRGSIIITICVSLIVILIVFGCIAKIFINKNNCTNNVIRVHKRIKCPDCEPFCNKRDDISTPRAGVDIPSFILPGLNLSEGTPN
What is the function of this protein?
Putative viral proton channel.  May play a role in virus entry.
What are the official names of this protein?
Glycoprotein NB.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses type B glycoprotein NB family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type III membrane protein.
Protein: ZNF2_HUMAN
Sequence: MAAVSPTTRCQESVTFEDVAVVFTDEEWSRLVPIQRDLYKEVMLENYNSIVSLGLPVPQPDVIFQLKRGDKPWMVDLHGSEEREWPESVSLDWETKPEIHDASDKKSEGSLRECLGRQSPLCPKFEVHTPNGRMGTEKQSPSGETRKKSLSRDKGLRRRSALSREILTKERHQECSDCGKTFFDHSSLTRHQRTHTGEKPYDCRECGKAFSHRSSLSRHLMSHTGESPYECSVCSKAFFDRSSLTVHQRIHTGEKPFQCNECGKAFFDRSSLTRHQRIHTGESPYECHQCGKAFSQKSILTRHQLIHTGRKPYECNECGKAFYGVSSLNRHQKAHAGDPRYQCNECGKAFFDRSSLTQHQKIHTGDKPYECSECGKAFSQRCRLTRHQRVHTGEKPFECTVCGKVFSSKSSVIQHQRRYAKQGID
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 2, Zinc finger protein 2.2, Zinc finger protein 661.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL11_FRATO
Sequence: MAKKKIEAIIKLQVAAGKANPSPPIGPALGQHGVNIMGFCKEFNAKTQGMEPGMPIPVEISVYSDRSFTFEMKTPPASYLIKKAINVKSGSSKPSKEFIGTITRAQLEEIAKVKDPDLTAADLDAAVRIIAGSARSMGVKVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: UREF_PSYCK
Sequence: MRIDDPSNAVSDLALLGLMQLISPALPIGAFAWSQGLESAFELGWVNNEAQLGEWLEGVLGDGLTRCELPVLARLQRCWANNDGDGLAFWNDWLHANRETAELSDEDTRLGQALIRLLNSLELQPQKALGHVELPEEPGYVTVFAWTAHQRQVPVRQALLGFAWGWLENQLAAACKALPLGHTAAQRLNETLRPQLVAAVDKALTLTDEQLGPILPGLALGSAQHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBBP4_XENTR
Sequence: MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPDGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGNLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDTEGGVDPEGQSS
What is the function of this protein?
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.  Component of several complexes which regulate chromatin metabolism.
What are the official names of this protein?
Histone-binding protein RBBP4, Retinoblastoma-binding protein 4, RBBP-4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: FPG_ECOBW
Sequence: MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLTHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: MUTL_HISS2
Sequence: MTIKILPPQLANQIAAGEVVERPASVVKELIENSLDAGATHIQIEIENGGANLIRIRDNGIGIAKDELHLALARHATSKIASLDDLEMILSLGFRGEALASISSVSRLTLTSRTAQQNEAWQVYAQGRDMETSITPASHPIGTTVEVANLFFNTPARRKFLRTDKTEFAHIDEVIRRIALAKPQVAFTLTHNNKLIHRYKSAVTNEQKIKRIATICGNDFMQNALHIDWKHNDLHLSGWVIQPQFARHQNDLNYCYINGRMVKDKVITHAIRQAYSEYLSNEKYPAFVLFIDLNPNEVDVNVHPTKHEVRFHQARLIHDFIYQGMTNALTSEQTNIPIQSEQSNPTKVAEPQGIWNLTTHNKGNRATAGKNIFAQQPKDYDKKSSQFKPHFAANYSEVTPKKAVQKAYAELLATHEEKTIASSTLPHQFTHNATHISEQKNVLHALALIENKALLLQQNQQYFLLSIQALQHFNIRLQLQQSNIAQQTLLIPILLRLNKQQYQSWQQQALFFQQSGFDFTDNSAQRRITLNRLPICLRTQNIQKIILQLLDQPHEKYTIFLTALCSHLEFPSLSTFSEAVNLLTKTEQQFSTQHQLEFQSLLVKIEWDHYLDKLQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: GLUQ_PHOPR
Sequence: MGIFSRLQSLFNVFMTTDTHYVGRFAPSPSGPLHFGSLIAALGSYLQARSQQGKWLVRIEDLDPPREIRGAADDILRTLEAYGLTWDGSVMYQSQRHGAYQDQIDQWLHGGDAYYCQCTRKQIKTAGGFYPGTCRHLHRSAENSAVRLNVDTPITYFVDRLHGQIDIPATLAQEDFIIRRRDGLYAYNLAVVLDDIEQNITEVVRGADLIEPTGRQIGLYRQLQHPEVSYLHLPLAVTDNGNKLSKQNHAPAIDKSHPVPALIAAMSFLGMTPPATLIKEELKDVLQWGINAWCIDNLPKMTEIILTKTH
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: HBA_HELMA
Sequence: MVLSPADKSNVKATWDKIGSHAGEYGGEALERTFASFPTTKTYFPHFDLSPGSAQVKAHGKKVADALTTAAGHLDDLPGALSALSDLHAHKLRVDPVNFKFLSHCLLVTLASHHPAEFTPAVHASLDKFFSAVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: NU5M_POLOR
Sequence: MSISQLSQMFMTCLSLTMIILILPITFSFITKPSNKWPFQVKNAVKLSFFVSLIPSITCLNLNLQSFTIYYQWFSISSTKINISLQFDQYSMIFMTIALYVTWSILEFAIYYMHTDILINRFFKYLLTFLIAMMILVTANNMFQLFIGWEGVGIMSFLLIGWWYGRADANMAALQAVIYNRVGDIGLMMTMSWLLINTNSWDIQQLFGLTKNMDTTLPATGLLLAATGKSAQFGLHPWLPAAMEGPTPVSALLHSSTMVVAGIFLLIRLHPLIENNNNILTAALCLGAITTLFTATCALTQNDIKKIVGFSTSSQLGLMMVAIGLNQPQLAFLHICTHAFFKAMLFLCSGSIIHSLNDEQDIRKMGGINKTLPLTSSCLTIGSLALMGTPFLAGFFSKDAIIEAINTSHLNAWALVLTLIATSFTAVYSLRIIYFVLMNHPRTLPLSPVNENNPLIANPIKRLAWGSIIAGLILCQYILPNKTQTLTMTPMLKLTALIVSLLGLLTALELASMANKQIKINPTKFTHNFSNMLGFYPHIMHRLMSKLPLMLGQISATQMSDQLWMEKLGPKGIAHTQLLVTQKITHVHKGLIKTYLSIMMLSIIIITIIIMIT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NUSB_AGRFC
Sequence: MSDVENGGEPRQPSVKPANQRGAARLAAVQALYQMDVGGTGVMEVVAEYEAHRLGQEVDGDTYLKADPSWFRSIVSGVVRDQTKIDPLVRSALLEDWPLSRLDATVRAILRAGTFEILERKDVPVAVIVTEYVEIARAFFEHDEPKLVNAVLDRIAKQVRGEAKR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: LEPA_CLAMS
Sequence: MSPLATKALRPAATDPASIRNFCIIAHIDHGKSTLADRMLQMTGVVDSRSMRAQYLDRMDIERERGITIKSQAVRMPWELDGQTYALNMIDTPGHVDFSYEVSRSLAACEGAILLVDAAQGIEAQTLANLYLALENDLTIIPVLNKIDLPAADPDKYAAELASLIGGDPSDVLRVSGKTGAGVEDLLDRVSRTIPAPVGDPDAAARAMIFDSVYDAYRGVVTYVRMIDGKLSPREKISMMSTRATHEILEIGVSSPEPTPSDGLGVGEVGYLITGVKDVRQSKVGDTVTTAARPATEALPGYTEPLPMVFSGLYPIDGSDYPDLRDALDKLKLSDAALVYEPETSVALGFGFRCGFLGLLHLEIITERLSREFGLDLITTAPSVIYEVTSEDKKTVTVTNPSEFPGGKIVSVSEPVVKAAILAPKDYVGTIMELCQSRRGILLGMEYLGEDRVEIRYTMPLGEIVFDFFDNLKSKTAGYASLDYEPAGSQDSDLVKVDILLQGEQVDAFSAIVHRDKAYAYGVLMTGRLRELIPRQQFEVPIQAAIGARIIARESIRAMRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKMVGRVEVPQEAFIAALSGDTEKKAK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SSRP_BACSU
Sequence: MPKGSGKVLSQNKKANHDYFIEETYETGIVLQGTEIKSIRAGRVNLKDSFAKIERGEVFLHNMHVSPYEQGNRYNHDPLRTRKLLMHRKEINKLIGLTKEKGYSLVPLKLYLKNGFAKVLLGLGKGKKNYDKREDLKRKDAKREIERAFRDSQKGF
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation (By similarity).  Required for trans-translation (PubMed:11395451).  Probably required for sporulation; deletion of the gene for tmRNA impairs sporulation via its effect on trans-translation, and as smpB is required for trans-translation under non-stress conditions, it is also probably required during sporulation (PubMed:18673456).
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ARO1_COCP7
Sequence: MAAPTTIKILGRDSIVADFGIWKRHVADDLLTNCSSSTYILISDTTLTPLYVPSFQAAFENAASGLTPKPRLLTYAIPPGELSKSRQTKADIEDWMLSRQPPCGRDTVIIALGGGVIGDLIGYVAATYMRGVRFVQVPTTLLAMVDSSIGGKTAIDTPHGKNLIGAIWQPQKIYLDMEFLNTLPEREFINGMAEVIKTAAISSEEDFAALEKNADAILSAVKSENTPERPRFGGIQEILKLTILASARFKADVVSKDEREGGLRNLLNFGHSIGHAIEGILAPQILHGECVAIGMVKEAELARHLGLLKNVAVPRLVKCLASYGLPTSLKDSRIRRLSAGKHCSVDQLLAFMAVDKKNAGPKKKVVLLSAIGRTHEQQASVVSNEDIKIVLAPSIEVSPGVPKSLQVTCTPPGSKSISNRALVLAALGSGTCRIKNLLHSDDTEVMLNALERLGAATFSWEEEGEVLVVHGNGGTLKASPEELYLGNAGTASRFLTTVATLANNGTVSSTVLTGNARMKQRPIGALVDSLRANGAGVEYLETNGCLPLKIDASGGFAGGEISLAAKISSQYVSSLLMCAPYAKEPVTLKLVGGKPISQQYIDMTTAMMRSFGIDVKRSTTEEHTYHIPQGKYVNPAEYIIESDASSATYPLAVAAITGTTCTIPNIGSKSLQGDARFAVDVLRPMGCEVSQSEYSTTVTAPKDGVLKPLPNVDMEPMTDAFLTASVLAAVATGSPNRTTRIFGIANQRVKECNRIRAMKDELAKFGVICREHDDGLEIDGIDRSTLLQPPHGVHCYDDHRVAMSFSVLSLTAPKPTLILEKECVGKTWPGWWDTLAQLFKAKLEGVELKSSTKQKAEKPAASIFIIGMRGAGKTTSGLWAAKALKRPFIDLDVELESTIGKTIPEIIKERGWEGFREAELALLQKVIREKPTGYVFACGGGIVETQEGRDLLVQYHKANGNVLLLMRDIKEVMDFLKIDKTRPAYVEDMMGVWLRRKPWYQQCSNFQFYSQQSTQDEMGRALESFSRFLRVITGEVDHLSLLKKKPQSFFVSLTLPDLRPSAEILGDVTLGSDAVELRVDLLVDPSSANDIPSVDYVAEQISMLRSRVSLPLVFTIRTKSQGGRFPDDAHDAALDLYRLAVRMGSEFVDLEVTFPEHILRAVTEMKGFSKIIASHHDVSGSLSWANGSWGQFYNKALQYGDIIKLVGVAKCLDDNIALRKFKTWAQDAHEIPVIAINMGEKGRLSRILNGFMTPVSHPKLPFKAAPGQLSAQDIRKGLSLMGEIEPRKFAIFGKPVSASRSPAMHNALFAQVGLPHAYSRLETDNVEDVREFIHAPDFGGASVTIPLKLDIMPLLDEISPEAQVIGAVNTIVPIPRGPGDMTGYPRLIGYNTDWQGMVRCLRHGKAISPSFADTAVPGLVIGGGGTARAAIHALYSMSYSPIYLIGRSEAKVAEMASTFPEKYSVQVLKDATSLENLPMVAIGTIPGDRPIDPSMREVLCRLFENAARVDSELSAKGEVPAKRVLLEMAYKPDITPLSQLASDSGWSTIPGLEALVGQGVHQFELWTGITPVYQDARAAVMNPGTDNRG
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_HBVCJ
Sequence: MDIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: F91A1_DANRE
Sequence: MNTDVEFHIRQNYPWNKLPANVKQSLGNSQREYDKQVLLYSIRNQLRFRNNLVRHVKKDERKYYEELLKYSREHLMLYPYHLSDIMVKGLRVTPFSYYISIMEDIMNCEKSYDSLPNFTAADCLRLLGIGRNQYIDLMNQCRSSKKFFRRKSARDLLPAKPVEITVEPWWVVQTGYITEDDIRICSVAEKAAIDKMIDSGPQLAGSMEYNVVLSLYNRGYIYLDVPISDDSCISVPPLEGFVMNRVQGDYFETLLYKIFVSIDEQTNVSELANVLEIDLGLVKNAVSMYCRLGFAIKKGQVISPDQLHPSWKSAPSVNRLKGTMDPQKMLLSWEGGSPVMEAGSSATDTDTTSLEDQDTASVSSLSIPAAPTKRIAFLFDSTLTAFLMMGNLSPNLKSHAVTMFEVGKLSDETLDSFLMELEKVESTAEGEAQRYFDHALTLRNTILFLRYNKDLTPDQGPDVPNIGLPLDLLRCESLLGLDPATCSRVLNKNYKLLVSMAPLSNEIRPISSCTPQHIGPAIPEVSSIWFKLYLYSVTGQGPPSLLLSKGSRLRKLPDIFQAYDRLLITSWGHDPGVVPSSNVLTMLNDALTHSAVLIQGHGMHGHGETVHVPFPFDEEDLKGEFSYSNMCAHKALKILRDKVDLEHQCGYITMLNHNNRHRRRASDADGDAELCGVLDANGSNESFELVTEENNGDGGKKQGTEASSSEDEWVPLELCFGMPLFSSELNRKVCQRIVSHKLCSKDSLQELLHSSRKLALKVLSFVQSFQDGKQPADPDSGVSGPLSQPPAESGVPLPAINLLFKDGELKEWSGRAPPSLHISAPQRDQPT
What is the function of this protein?
As component of the WDR11 complex may act together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1.
What are the official names of this protein?
Protein FAM91A1.
What is the protein family that this protein belongs to?
Belongs to the FAM91 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle.
Protein: RL9_CALBD
Sequence: MKVVLLQDVKGLGKKDSVVEVNDGYARNYLIPRKLAVPATEGLEKHLKEKKEAEQKKKEKELEAAKDLASKLEKSQIIIKAKAGENGKLFGSITNKEIAEEIKKQLGFDINKKKIELDDPIKLIGSYDVVIRLYQGVVAKLKVHVTAS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DAPB_STAES
Sequence: MNILLIGYGAMNQRVARLAEDKGHEIVGVIDRTSKASTPYSQYQHISECKEADVAIDFSNPELLFPLLEEQFNLPLVIATTGEKETLIQKLETLSQRTPVFFSANMSYGVHALTKILETAVPLLQDFDIELTEAHHNKKVDAPSGTLVKLYDVIKELRDNVSPVYDRHEKTEKRTHDEIGIHAVRGGTIVGEHDILFAGTDETITISHKAQSKDIFANGAIGAAEKLIHKNPGFYTFNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGB1_SOYBN
Sequence: MGAFTEKQEALVSSSFEAFKANIPQYSVVFYNSILEKAPAAKDLFSFLANGVDPTNPKLTGHAEKLFALVRDSAGQLKTNGTVVADAALVSIHAQKAVTDPQFVVVKEALLKTIKEAVGGNWSDELSSAWEVAYDELAAAIKKA
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin C1, Nodulin-50, N-50.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: QCRA_STRCO
Sequence: MSSQDIPEENLPAEQDRPHGAAARPADETNPFADPGLPPHEPRVQDVDERAAKRSERTVALLFTLSMLATIAFIAAFVAIDVDKSVYIFPLGHISALNFALGMTLGVALFAIGAGAVHWARTLMSDEEVADERHPIEASPEVRAKVHADFKQGAKESVIGRRKLIRNTMLGALTLVPLSGVVLLRDLGPLPGTKLRHTLWSKGKLLVNMNTNEPLRPSDVAVGSLTFAMPEGLEEHDEDFQNEIAKAALMIIRLEPDSIKDKRELEWSHEGIVAYSKICTHVGCPISLYEQQTHHALCPCHQSTFDLADGARVIFGPAGHALPQLRIGVNDEGYLEALGDFEEPVGPAYWERG
What is the function of this protein?
Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
What are the official names of this protein?
Cytochrome bc1 complex Rieske iron-sulfur subunit, Cytochrome bc1 reductase complex subunit QcrA, Rieske iron-sulfur protein, Ubiquinol--cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL25_RICCK
Sequence: MSKILELEAQSRTEFGTGAARALRREGRVPAIIYGAGKTPVSISLEEKEITKYYRKPAFISQLINLTIDKKQYKVLPKAVELHPVTDIVRHVDFVFLEEKKQKMEVPVVYEGKERALGVKRGGYFNIVKRRVTLLCDVNNIPRNVTIDVTNMPIATSLNSSKIVLPKGCSFASKKEFVLATIIGRRGVKTEAEGEQQAAAEAGK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: TOB1B_XENLA
Sequence: MASSENAPFCVKFMKCGENSEYFLKGYEAMKQIQSDESLQLTEEREALVLKEKDKCVYICDPFSGAAFSHLKKLGCRIVGPQVVIFCMESQRRVPRAEYPVYNMAMADVTISCTSLDKETREDVHHYVQIMGGCVYRDLNVSVTHLIAGEVGSNKYLVAASLEKPILLPSWVKELWEKSNQRIIRYSDVNMTEYLCPIFRGCTICVTGLSSLDRKEVQRLTALHGGEYTGQLKMNESTHLIVQEAKGQKYECARKWIVHCISVQWFFDSIEKGFCQDETMYKIEPASTIKSVPDTSTPTGGNSKPNSRTLYDVSQISNISTSCVNESAFNSAMASRLDPPADTLENLDISSLQAPDDLLDGCRIYLCGFGGRKLDKLRKLINNGGGVRFNQLTGDVTHIIVGETDEELKQFLNKTQHRPYVLTVKWLLDSFAKGHLQPEEIYFHSSYQQTEMPSPFEPAINLTANKMSSTRDPLNHTRNHQADEDLLSQYTENNSTLIEDEHPKTSNTNSISQITCSEDLTTCTSQSGLADPSTIIEGGLFSRKQFMVLGFLEEDEACIIDIRKKSAGKVLSSQKRAIADYAVVPLLGCEVESTVGEVVTNAWLGMCIEQEKLLDPHSNALFTPVPFLEGSTPLRECVLSVSQFMGAERDSLVYLAGLLGAKVQEFFVRKANPKKGMFARSHLDLKDAEGSKYEAAKKWNLPAVTMNWLLQCARTGKKADEDSYLVDNVPEEDKDESFINQTYKPQAIRLSMHAPCHLENHPEALTKAAVTPLDMNRFKSKACQSVISQHNKNPQTSGGESKVLQREPSLHLDTPSKFLSKDKLFKPSFDVKDALAALETPGGPNQKNRTQSTPLSEVIGRNLQLAIANSTRQTAAVTASPQLKAAEKKEFDNSKLLINVVICVSKKLIKKQGELNGIAASLGAEYRWCFDESVTHFIYHGRQNDMSREYKSVKERSGIYIVSEHWLFACSEQQKRVPEALYPHTYNPKMSLDISAVKMGSYTASKFSADTSLQQDENSELQLQQNNKFGETSDDQVKKAAGDGNPQNPSKDVKGALTQTLEMRENFQRQLQEFMSATSVVKPRGSVGRAGFDNSPCTPEGARSTRNGRSRVLEALRQSRQAMTDLNTEPSQNEQIIWDDPTAREERAKLVSNLQWPDSPSQYSEQLQHNMNDAGGNYTPAKESLTDTEIAELEACEFEPKSAMRTPVIENNLQSPTKPDHLTPTPQAPSIAFPLANPPVAPQPREKPVQPFSKEETLKERRFQLSSLDPQERIDYSQLIEELGGVVIEKQCFDPSCTHIVVGHPLRNEKYLASMAAGKWVLHRSYLEACRAAKRFIQEEDYEWGSMSILSAVTNINPQQRMLAEAAMRWRKKLQGIKQNMGIAEGAFSGWKVILNVDQTKEPGFKRLLQSGGAKVFAGHSSPLFKEASHLFADFSKLKPDEPRVNVAEAAAQGVNCLKPEYIADYLMKELPPPMNNYCLPDAIPYVRVTGTGLSRKRKTSGDVSDVKRSRHY
What is the function of this protein?
Has dual roles in initiation of DNA replication, and regulation of checkpoint responses.  Required for DNA replication initiation but not for the formation of pre-replicative complexes or the elongation stages.  Necessary for the loading of replication factors onto chromatin, including gemc1, cdc45, DNA polymerases and components of the GINS complex such as ginsl/sld5.  Binds chromatin in both S-phase cyclin-dependent kinase (S-CDK)-independent and S-CDK-dependent modes.  Chromatin binding is required for the action of S-CDK, which in turn triggers the formation of preinitiation complexes of DNA replication.  Its role in checkpoint activation is independent of the DNA replication role.  In response to DNA damage, triggers the recruitment of checkpoint signaling proteins on chromatin, which activate the chek1 signaling pathway and block S-phase progression.  Increases the kinase activity of atr to numerous substrates, and is required for the phosphorylation of Rad1.
What are the official names of this protein?
DNA topoisomerase 2-binding protein 1-B, DNA topoisomerase II-binding protein 1-B, TopBP1-B, Xmus101.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Chromosome. Note=Associates with chromatin.