PharMolix/UniProtQA huggingface dataset:
Protein: VP7_ROTBT
Sequence: MYGIEYTTILTFLISIILLNYILKSTTQMMDYIIYRFLLITVTLFALTKAQNYGINLPITGSMDTAYANSTKEETFMTSTLCLYYPVEASNQINDGEWKDTLSQMFLTKGWPTGSVYFKEYTNIVDFSVDPQLYCDYNLVLMKYDQNLELDMSELADLILNEWLCNPMDITLYYYQQTGESNKWISMGSSCTVKVCPLNTQTLGIGCQTTQCGSFEIVAENEKLAIVDVVDGINHKINLTTTTCTIRNCKKLGPRENVAVIQVGGSNILDITADPTTNPQIERIMRVNWKEWWKVFYTIVDYINQIVQVMSKRSRSLNSAGFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: ATG7_CRYNB
Sequence: MAPLQFQPLASQPTPAFWAALAAHKLNHLKLDDSHLPITAQIEPAKRVLINKERVDDTADVGIDGSLVVGGDAFEAERGRLPPNAVSVTGTLKIFNTIEEFKDTSAKKRLFDDLVSQMLESFDTDRPVLNPFLLVTFADLKKYVYHYWFAFPALVSSPAWVMDGEFMPVDEIEDIRNLAQSHFQHNTAAFLLKGAAPHLSAAPLSSCSTFYDKTQSEMVTVVFHDTSSLPSNPGWGLRNVLYYLSAKHGITSLVVICLRGGSSSTQASLSLSSPPSTAPAKPPQAVGWERHPSGKLSPRVADLGPMMDPTRLAAQAVDLNLKLIKWRLLPALDLDKISGTRCLLLGAGTLGCYVARILMGWGVRNITLVDSSTVSYSNPVRQPLFTFSDCLNGGLPKAPTAAKKLQEIFPGVNAQGVVLGIPMPGHPISSSDDAVEKDVAKLEALVKSHDAVFLLMDSRESRWLPTVLGRKWGKVVVNAALGFDSFLVMRHGAGAGARRIQWDEGGVGEKGLGCYYCNDIVAPADSLSDRTLDQMCTVTRPGVAPIAAAMAVELLISVLQHPLGVHAPAERPDTAETSTSTKTSPLGCVPHQLRGQMYQWKTQIVEGEAFDRCTGCSDYVLNEYETNGFAFLRRVFNEKDYLEKVTGLDELYRESEKVIEGMEGLDWDSEGEE
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy.  Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine.  Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Plays a role in the regulation of filamentous growth and chronological longevity (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: PCNA_CATRO
Sequence: MLELRLVQGSLLKKVLESLKDLVTDANFDCSASGFSLQAMDSSHVALVALLLRSEGFEHYRCDRNPSMGMNLNNMAKMLKCAGNDDIITLKADDGSDTVTFMFESPTQDKISDFEMKLMDIDSEHLGIPEAEYHAIVRMPSAEFARICKDLSSIGDTVVISVTKEGVKFSTRGDIGTANIVCRQNTTVDKPDEATIIEMNEPVSLTFALRYLNSFTKATPLSNNVTISLSSELPVVVEYKIAEMGYIRFYLAPKIEEDDEEQSLEYQA
What is the function of this protein?
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
What are the official names of this protein?
Proliferating cell nuclear antigen, PCNA, Cyclin.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBFA_BARHE
Sequence: MKNAEPSQRQLRVGEQVRHAVAHILQQGILLDNLLKNMVISVVEVRMSPDLKIAICFVSPLSTVHNASRADVVNALNKHSRFIRGEISHSLRQMKYMPELRFRLDNSFDNFSKIDALLRSPEVARDLHHNDKVGD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_TRINC
Sequence: MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNVGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTELVQWIWGGFSVDKATLTRFFAFHFLFPFLVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLIMLTVLSALVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAIVPALHLSKQRSMMFRPLSQCLFWFLVAILFTLTWIGGQPVEYPYIIIGQMASALYFLTLLVFMPLTSLVENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ULAG_SALSV
Sequence: MSKVQSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKTGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPQTCVDLWVGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDVRAVNYLFKTPGGNLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMAESLNTKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_LACCB
Sequence: MPTKIAVLGAGSWGTVLANLLTENGHEVDLWSHNPDQVALMKRTHQNEHYLGAEFTLQPALHVTADLGQALDQAAVILFVVPTNAIRSVAEQVKPILQAHKGRGEQPIIVHAAKGLERGSELRISQVLAEVLPKELIQGIVVISGPSHAEDVATHDITTLTAASDDLKLAEKVQKLFMNDYFRLYTNTDVIGVEIGAALKNVIAIGAGALHGLGYGDNTKAALMTRGLAEISRVGVKLGAEPLTFIGLSGVGDLIVTCTSVHSRNWRAGNALGQGEKLPDVLKNMGMVVEGVSTTKVAHQMARELDVDMPITDAIYQVLYENAPIRTVITDLMKRSGKPEFDFDNASLQKP
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFU5_ARATH
Sequence: MKGLTRLLNSLSRHTASVTCSPSSSSLLISRRSLFISAATHFPVNFSESITTNASRNCSRSSSFPFNWIEQRRTMFIQTQSTPNPSSLMFSPGKPVMEIGSADFPNSRSAMSSPLAKAIFAIDGVVRVFYGSDFVTVTKSDDVTWDILKPDIFAVVMDFYSSGQPLFLDSQATAAKDTAIHEDDSETVAMIKELLETRIRPSVQDDGGDIEYCGFDTETGIVKLRMQGACSGCPSSSVTLKSGIENMLMHYVSEVKGVEQEFDGEEEGTSSGPME
What is the function of this protein?
Molecular scaffold for [Fe-S] cluster assembly of mitochondrial iron-sulfur proteins.
What are the official names of this protein?
NifU-like protein 5, mitochondrial, AtNfu-I, AtNfu5.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MURA_MYCTU
Sequence: MAERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVARITAPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGAHCNIEHGCVVARAETLRGAEIQLEFPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRLHPTEHRVIGDRIVAATWGIAAAMTRGDISVAGVDPAHLQLVLHKLHDAGATVTQTDASFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLVSLGAEIERVCC
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCDA_ANAPI
Sequence: MSLTQGMKAKQLLAYFQGKADQDAREAKARGELVCWSASVAPPEFCVTMGIAMIYPETHAAGIGARKGAMDMLEVADRKGYNVDCCSYGRVNMGYMECLKEAAITGVKPEVLVNSPAADVPLPDLVITCNNICNTLLKWYENLAAELDIPCIVIDVPFNHTMPIPEYAKAYIADQFRNAISQLEVICGRPFDWKKFKEVKDQTQRSVYHWNRIAEMAKYKPSPLNGFDLFNYMALIVACRSLDYAEITFKAFADELEENLKAGIYAFKGAEKTRFQWEGIAVWPHLGHTFKSMKNLNSIMTGTAYPALWDLHYDANDESMHSMAEAYTRIYINTCLQNKVEVLLGIMEKGQVDGTVYHLNRSCKLMSFLNVETAEIIKEKNGLPYVSIDGDQTDPRVFSPAQFDTRVQALVEMMEANMAAAE
What is the function of this protein?
Involved in the acrylate pathway for the conversion of D-lactic acid to propionic acid.  Catalyzes the reversible dehydration of Lactoyl-CoA and 2-hydroxybutyroyl-CoA to acryloyl-CoA and crotonyl-CoA, respectively.
What are the official names of this protein?
Lactoyl-CoA dehydratase subunit alpha, (R)-lactyl-CoA dehydratase component E II, 2-hydroxybutyroyl-CoA dehydratase.
What is the protein family that this protein belongs to?
Belongs to the FldB/FldC dehydratase alpha/beta subunit family.
Protein: PROA_GEODF
Sequence: MTVAEKIRKIAADARAASLAMARLSSAAKNELLLRMAEALENNAPLITAENARDLEAGQQKGLSAAMLDRLMLDESRIKAMADGLREVAALPDPVGEVTHMWKRPNEITVGKMRIPLGVIGIIYESRPNVTSDAAALCLKAGNAVVLRGGSEAIHSNLAIAGLLQDQMRKLGIPVAALSLIPFPERAGVTEMLKQEEFIDVIIPRGGESLIRFVVEHSKIPVIKHYKGVCHIFVDATADFGMAEKIIINSKTQRPGVCNALETLLIHKDVAETFVPRIHEALSTLKVELRGDEAFRQFAPGVKAATEEDWYAEYLELILAARVVDDLDEAIAHINKYGSLHTEAIITSDYANSQRFLREVNSSVVLVNASTRFSDGNQLGLGAEIGISTTKLHSFGPMGLEDLTTTKFIVYGEGQIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_RHIL3
Sequence: MSKGIVLLAAGGTGGHVFPAEALAFKLKERGYSVHLVTDSRAERYAGKFPAEEIHVVPSATIGSKNPVAVARSLWTLWSGMRAAKKLIQRLQPVIVVGFGGYPTVPPLLAATRLGVPSMIHEQNAVMGRANKALATRVQAIAGGFLPEGGAAFPDKTVTTGNPVRPAIIAAAEVPYTPSHPGEAFNLVVFGGSQGAQYFSKALPTAISLLDDALRVRLRITQQVRPEDMEMVSGCVARLEMGADIAPFFTDMAERLARAHLVICRSGASTVSEISVIGRPAVLVPYPHALDHDQAANAAALAATGGAKVIAQSELSPEKIAAILTAVMNDPEKLSHMAAAAKLAGKPDAANLLADMVEAIAARRTIAEFKRTRA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PNCB_DICDI
Sequence: MSQSNTPLKRKKTENGYSENGSTTGATSNQIRELKRATTVDYVYRDQESKDKIKPLNGFVTPLLTDLYQITMAYSLWKNNRHEIPAVFDLYFRKSPFGGEFTVFAGLEEVIRFVSDFHYTKEEVGFIKEMIPDCEQEFLDYLSKLDSSSVTLYAMKEGSVVFPRVPLLRVEGPMILCQLFETTLLCLVNFASLVATNAARHRLAVGKEKVMLEFGLRRAQGPDGAMSASRYSYLGGADGTSNVLAHCFFGIPIRGTHAHSFITNYSGPDELLDASIKDTNGNVHNLLEMSQKYRDELGYTATNLSELVAFVAYARTFPNGLVALVDTYDTLASGVPNFICVALALHQLGYKAVGIRLDSGDLSYLSKASRKLFKQIGEQFKIDYFEKFSIVASNDLNEPTIIALNRQGHEIDVFAIGTNLVTCQAQPALGCVYKLVEINGSPRIKLSQEANKITLPGRKTAYRLFGSEGHPLVDLLVDDNDMIKDGSKQIPQVGKKVLCLHPFEEQKRVIVTPVQIEKLHHIVFEKGQLTMPLPALNDIREYCFQQISKVREDHLRNSNPTPYKVSVTKELFDTLHNLWLDSVPIKEMK
What is the function of this protein?
Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.  Helps prevent cellular oxidative stress via its role in NAD biosynthesis.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: DMA_SALTI
Sequence: MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLNTDFSRYILADINSDLISLYNIVKLRTDEYVQASRELFMPETNQAEVYYQLREEFNTCQDPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKRPYFPEAELYHFAEKAQNAFFYCESYADSMARADKSSVVYCDPPYAPLSATANFTAYHTNSFSLTQQAHLAEIAENLVSNRIPVLISNHDTALTREWYQLAKLHVVKVRRSISSNGGTRKKVDELLALYQPGVATPARK
What is the function of this protein?
An alpha subtype methylase, recognizes the double-stranded sequence 5'-GATC-3' and methylates A-2 (By similarity) (PubMed:12654995).  May be involved in methyl-directed DNA mismatch repair, initiation of chromosome replication and gene expression (By similarity).
What are the official names of this protein?
DNA adenine methylase, DNA adenine methyltransferase, Deoxyadenosyl-methyltransferase, Orphan methyltransferase M.StyCDamP/M.StyTDamP, M.StyCDamP/M.StyTDamP.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: RAEP_CANAX
Sequence: MDNCDVLIIGTGLQESILAAALSWQGTQVLHIDSNTYYGDSCSTLTIEQLKKWCGDVNSGKIHQFQDAQIYIPGGKQSNQYTSKDYGIDLTPKIMFCQSDLLSLLIKSRVYRYLEFQSLSNFHVFENDDFQQKVNATTKQDIFTDKSLSLMTKRYLMKFLKFLLLDPDYKQRVKPYADTPIQVFLQQEFKLEEPQINELVYSIGLSYKEQTSTKQALIRMKRFLSSFDVYGKFPCMVSKFGGPGELSQGFCRSAAVAGTTYKLNTNLTDFDPISKIAHFNDGSHIKINEKIIISPTQLPKFLQSSYNKVVENLQPYYVTRLVTVVRRDCKEWMSGNESSAIVVFPPHSLPTDNQHSVQVIIQNGNSGVCPDGQAIWFSSTVEQDLSRAKVDLESAFEKMETSLLRESSEEIVNDILGDNNNNNNNNNNNNNNNNNNNNNDFVMNAQGTTTPVLVNSFKLGSSLINFVPKDKLEIVCKLGYVEKTFINPDLSNIFKPTKTNNIVYKDVEDANNEIIFTNMPSSELSYDGIITDVKSIYQRITGTTDDFFDVDFEDEEDEYDRNNQPVVQPKRSSVVGGIVGGGSITSLTALREQHNENNHSDNAIDSDEDEDEDINDMNDNEEEDDHGRGPEPFGADEMEL
What is the function of this protein?
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex.  Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B.  The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane (By similarity).
What are the official names of this protein?
Rab proteins geranylgeranyltransferase component A, Rab escort protein, REP.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
Protein: PVK3_DERAT
Sequence: GGSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, DerAt-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCAD_ECO5E
Sequence: MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVGVVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRFVAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSVLPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITSMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVILGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGSLLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV
What are the official names of this protein?
Uncharacterized MFS-type transporter YcaD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CWP27_ARATH
Sequence: DVGKFK
What are the official names of this protein?
60 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: JZ54B_CHIGU
Sequence: MRFHTLLFLSFLLLVSCALICTAQHPGLKKSGMFHENVGKGQHIEKKRSCIERMQTCEVEAGLPCCSGAPCICPYIGDCICIQ
What is the function of this protein?
Inhibits TTX-sensitive sodium currents in rat dorsal root ganglion (DRG) neurons.
What are the official names of this protein?
U25-theraphotoxin-Cg1a, U25-TRTX-Cg1a, Jingzhaotoxin-54.2, JZTX-54.2, Peptide F1-20.74.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 03 (aga-4) subfamily. JZTX sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRK_THEVO
Sequence: MINLKIEENVKESQNVNTLYFNWDQDIRPGQFAMIWIPGYGEIPMSFSGLGRRKSITVKAYGSASRKLTELKAGDDLFLRGPYGNGFDVREGRKLLVGGGSGIVSLYPIADQETDALISAKTRDELIFKDRFPESRRFIATDDGSDGFHGFAHELLQRINIDSYEAIYVCGPEQMMYKVLQVLKGRKVFVQFSLERTMKCGIGICDSCSLGGKQVCKEGPVFNIEELIGNPEFGVYRTTYSGRRIRLNVK
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Probable dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: DRMH1_ARATH
Sequence: MWDETVAGPKPEHGLGRLRNKITTQPLDIKGVGEGSSSKTVAAVAGSPGTPTTPGSARKENVWRSVFHPGSNIATRGMGTNLFDKPSHPNSPTVYDWLYSDDTRSKHR
What are the official names of this protein?
Dormancy-associated protein homolog 1, Auxin-repressed protein 1, AtARP1, DRM1 homolog 1, Dormancy-associated protein 2, AtDRM2.
What is the protein family that this protein belongs to?
Belongs to the DRM1/ARP family.
Protein: RUVC_PSELT
Sequence: MIIFGVDPGFGILGYGVLSVSGNSFQHVSHGTIQTEKQQNIALRLKVLYEELSNVIDNFKPSEIAMEKLFFSRNITTAISVGEARGIVLLLAAQRNIPVFEYTPHEIKKAVTGSGKASKKDVQQMIKILLNLKELPKPDDAADGLAIAWCHCAVRNITRRFS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MVP_CLVK
Sequence: MDTSVPVISSDYIHSARTEYKLTNDESPITLQFPSTLERTRVRIMGKCMKVDHVVIEYRNQVPFNAQGSVIVTIRDTRLSDEQQDQAQFTFPIGCNVDLHYFSASYFSIDDNVPWQLLYKVEDSNVKNGITFAQIKAKLKLSAAKHSTDIKFKQPTIKILSKDYGPDCVDFWSVGKPKPIRRLIQNEPGTDYDTGPKYRPITVQPGETWATKSTIGRYTSMRYTRPNPIDIDDSSSKQYTSEAEFPLRGLHQLPEASLDPGDSISQTQSMSKKDIESIIEQTVNKCLIAHRGSSHKDL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Begomovirus genome is shuttled out of nucleus by Nuclear shuttle protein (NSP) and the movement protein transports the DNA-NSP complex to cell plasmodesmata and facilitates further movement across the cell wall (By similarity).
What are the official names of this protein?
Movement protein BC1, 33.7 kDa protein, Movement protein BL1.
What is the protein family that this protein belongs to?
Belongs to the begomovirus movement protein BC1 family.
What are the subcellular locations of this protein?
Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host microsome membrane; Peripheral membrane protein; Cytoplasmic side. Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Found on ER-derived vesicles.
Protein: APJ_XENTR
Sequence: MATDEFSSSTTPSYDYYDYTNESGLPPCDETDWDLSYSLLPVFYMIVFVLGLSGNGVVIFTVWKAKPKRRSADTYIGNLALADLAFVVTLPLWATYTALGFHWPFGSALCKLSSYLVLLNMFASVFCLTCLSFDRYLAIVHSLSSAKLRSRSSILVSLAVIWLFSGLLALPSLILRDTRVEGNNTICDLDFSGVSSKENENFWIGGLSILTTVPGFLLPLLLMTIFYCFIGGKVTMHFQNLKKEEQKKKRLLKIIITLVVVFAICWLPFHILKTIHFLDLMGFLELSCSTQNIIVSLHPYATCLAYINSCLNPFLYAFFDLRFRSQCFFFFGFKKALQGHLSNTSSSLSAQTQKSEIHSLATKV
What is the function of this protein?
Receptor for apelin receptor early endogenous ligand (apela) and apelin (apln) hormones coupled to G proteins that inhibit adenylate cyclase activity.  Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for apela hormone, promoting endoderm and mesendoderm cell migration and regulating the migration of cells fated to become myocardial progenitors, respectively.  Promotes angioblast migration toward the embryonic midline, i. e.  the position of the future vessel formation, during vasculogenesis.  May promote sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development.  Required for cardiovascular development, particularly for intersomitic vein angiogenesis.  Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility, and heart failure.  Acts upstream of the i/o type of G-alpha proteins in the differentiation of endothelium, erythroid cells, myeloid cells and cardiomyocytes.
What are the official names of this protein?
Apelin receptor, Angiotensin receptor-like 1, Angiotensin receptor-related protein, G-protein coupled receptor APJ.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Internalized to the cytoplasm after exposure to apelin (apln). After exposure to apelin receptor early endogenous ligand (apela), internalized from the cell surface into an endosomal recycling compartment, from where it is recycled to the cell membrane.