PharMolix/UniProtQA huggingface dataset:
Protein: ILVC_BURP0
Sequence: MKVFYDKDADLSLIKGKQVTIIGYGSQGHAHALNLKDSGVNVTVGLRRGGASWSKAENAGLAVKEVAEAVKGADVVMMLLPDEQIAAVYAQEVHANIKEGAALAFAHGFNVHYGQVIPRADLDVIMVAPKAPGHTVRGTYAQGGGVPHLIAVAQDKSGAARDIALSYAAANGGGRAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRVVTEETKKAMKQCLTDIQTGEYAKSFILENKAGAPTLQSRRRLTAEHQIEQVGSKLRAMMPWIAKNKLVDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MUTS_LIMRD
Sequence: MAKKTTPMMEQYQKVKDQYPDAFLFYRLGDFYELFNDDAVKGAQLLELTLTTRNHSAKNPIPMCGVPHRAVNNYIDILIDKGYKVAICEQMEDPKKAKGMVKRAVTRLITPGTQMDLNGEQARDNNYLAAISGQNGVFSIAYTDLSTGELKTTSLNNANDAVNELVNLQSKEVVVDGELPVEITTQFKQRNILQSHQPTVLKNAEISYLTQDLDDQAQQHVVALLVSYLLTTQKRSLAHMQKAIAYQPSSFMKIDHYSKTNLELMRNMRSGKRQGTLAWLLDETKTAMGSRLLKRWIDRPLINQNAISERQDKVQELLDHYFERSNLQQELIKVYDLERLAGRVAYGSVNGRDLIQLKTSLKQVPKIKYVLETLDSPVFEELQKQLDPLDDVADLIDQSIIEEPPIAVTEGGVIKDGYNDQLDQYRDAMNNGKQWIVDLQEHERKLTGINNLKIGYNHVFGYYIEVTKVNLDKLPKDRYERKQTLVNAERFSTPELKEKEALIMGAQEKSTALEYDIFVKIREQVKGQITRLQKLAQQLAELDVLQSFAVVSEDYHFVRPEMNTGHVLKIKDGRHPVVEKFMGHQEYVPNDVLMGEDTDILLITGPNMSGKSTYMRQLALIAVMAQIGCFVPAKSAELPIFDQVFTRIGAADDLISGESTFMVEMMEANNALTHATDRSLILFDEIGRGTATYDGMALAQAIIEYVHQHVRAKTLFSTHYHELTALENSLARLKNVHVGATEKDGELVFLHKVSAGPADKSYGIHVAKLAGMPSSLLKRADTILQKLEQKDVKLPNTPKPATDNYHTEPISAKINEAAPVKKEAAPVVEDNGQLELFATQPEKKESSVDRRILHQLKELNLMGMTPMDVMNQIYKWQQKLK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MTP_EBVG
Sequence: MEERGRETQMPVARYGGPFIMVRLFGQDGEANIQEQRLYELLSDPRSALGLDPGPLIAENLLLVALRGTNNDPRPQRQERARELALVGILLGNGEQGEHLGTESALEASGNNYVYAYGPDWMARPSTWSAEIQQFLRLLGATYVLRVEMGRQFGFEVHRSRPSFRQFQAINHLVLFDNALRKYDSGQVAAGFQRALLVAGPETADTRPDLRKLNEWVFGGRAAGGRQLADELKIVSALRDTYSGHLVLQPTETLDTWKVLSRDTRTAHSLEHGFIHAAGTIQANCPQLFMRRQHPGLFPFVNAIASSLGWYYQTATGPGADARAAARRQQAFQTRAAAECHAKSGVPVVAGFYRTINATLKGGEGLQPTMFNGELGAIKHQALDTVRYDYGHYLIMLGPFQPWSGLTAPPCPYAESSWAQAAVQTALELFSALYPAPCISGYARPPGPSAVIEHLRSLVPKGGLLLFLSHLPDDVKDGLGEMGPARATGPGMQQFVGSYFLNPACSNVFITVRQRGEKINGRTVLQALGRACDMAGCQHYVLGSTVPLGGLNFVNDLASPVSTAEMMDDFSPFFTVEFPPIQEEGASSPVPLDVDESMDISPSYELPWLSLESCLTSILSHPTVGSKEHLVRHTDRVSGGRVAQQPGVGPLDLPLADYAFVAHSQVWTRPGGAPPLPYRTWDRMTEKLLVSAKPGGENVKVSGTVITLGEQGYKVSLDLREGTRLAMAEALLNAAFAPILDPEDVLLTLHLHLDPSRADNSAVMEAMTAASDYARGLGVKLTFGSASCPETGSSASSFMTVVASVSAPGEFSGPLITPVLQKTGSLLIAVRCGDGKIQGGSLFEQLFSDVATTPRAPEALSLKNLFRAVQQLVKSGIVLSGHDISDGGLVTCLVEMALAGQRGVTITMPVASDYLPEMFAEHPGLVFEVEERSVGEVLQTLRSMNMYPAVLGRVGEQGPDQMFEVQHGPETVLRQSLRLLLGTWSSFASEQYECLRPDRINRSMHVSDYGYNEALAVSPLTGKNLSPRRLVTEPDPRCQVAVLCAPGTRGHESLLAAFTNAGCLCRRVFFREVRDNTFLDKYVGLAIGGVHGARDSALAGRATVALINRSPALRDAILKFLNRPDTFSVALGELGVQVLAGLGAVGSTDNPPAPGVEVNVQRSPLILAPNASGMFESRWLNISIPATTSSVMLRGLRGCVLPCWVQGSCLGLQFTNLGMPYVLQNAHQIACHFHSNGTDAWRFAMNYPRNPTEQGNIAGLCSRDGRHLALLCDPSLCTDFWQWEHIPPAFGHPTGCSPWTLMFQAAHLWSLRHGRPSE
What is the function of this protein?
Tegument protein that plays a role in the inhibition of host intrinsic defenses to promote viral early gene activation.  Interacts with host DAXX and thereby disrupts the complex between DAXX and ATRX.  Suppresses the DAXX-ATRX dependent deposition of histone H3. 3 on viral chromatin allowing viral transcription.  Targets also host SMC5/6 for proteasomal degradation in a CUL7 and calpain-dependent manner to support nuclear membrane-less replication compartment formation and lytic virus replication.
What are the official names of this protein?
Major tegument protein, MTP, Protein p140.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae MTP family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Note=Colocalizes with host DAXX at PML nuclear bodies.
Protein: HIS1_SYNPW
Sequence: MITVALAKGALLRESVERFQAAGLDFSAVLDPDNRQLMVPSTCGRARALLVRNGDVPVYVAYGQAQLGIVGYDVLREHQMPVAHLVDLGFGGCRMSVAVKNTSGYTRATDLPPHCRVASKFTRCARQYFDSIDLPVELVHLTGSVELGPITGIAEAIVDLVATGRTLRDNGLVAIEDLFHTTARLVGHPLALRLDQGELQSIIDVMQRSPHDAVGVN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERN3_MEDTR
Sequence: MDYQNQKSNENKHGEKLMMKNRSKFVGVRQRASGKWAAEIKDTSKNIRMWLGTYKTAEEAARAYDEAAFLLRGTNTRTNFSTTHSIPTNSPISLKLKNLLHRKSISNLSQSKNQCTLMSSSLQGAPIDNSIMVMENENKSSCSSEESKSLFWVQNQLVSEYNPYGVDMNMMNCSIGITPNTLQIDYSWPLPQQRINELPTLNDSVNVYGMNECYVEGTYESKYEYDVNYPLSHLFCFT
What is the function of this protein?
Transcription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs).  Binds to the GCC box (NF-responsive box) of ENOD11 promoter.  May act as transcriptional repressor of NF-responsive box-containing target gene promoters in root hairs.
What are the official names of this protein?
Ethylene-responsive transcription factor ERN3, ERF transcription factor ERN3, NF box-binding protein 3, Protein ERF REQUIRED FOR NODULATION 3.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LCTB_GEOSE
Sequence: MDYAFLGVVTAVLLGSITSLWTASVQATHRLSLDSLWVLVQWYGTMLLGFAMIYMILQANGHHVFTPSPSSAAGNRLSMLEDSLYLSGMTLLSVGYGDVTPVGIGRWIAIAEALLGYIMPAVIVTRTVFDSDRR
What are the official names of this protein?
Protein LctB.
Protein: SNR48_MOUSE
Sequence: METEPPPLEERRRLQEELSEFVESCCRTLEEVTASLGWSLDQLDPGDEAEAEDEIAICPYDSNHRMPKSSLTKHMESCRLRKLGYTKEEENEMYNPTFFYENLKIPSVTLNKDSQFQIIKQARTTAGKDGDCYSQRMYSSVPVEVPLNHKRSVCDLTQTDRLALYDFVIEETKKKRSGPQVIENDSDLFVDLAAKVNQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVIKVHMEELSSHWQEEQGRAGDAAEKNEERRSASVDSRQSGGSYLDVESSRHRRARSRSPHKRKRNKDKSSESRRRKERDGERHHSHKRRKQKI
What is the function of this protein?
Likely involved in U12-type 5' splice site recognition.
What are the official names of this protein?
U11/U12 small nuclear ribonucleoprotein 48 kDa protein, U11/U12 snRNP 48 kDa protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROA_PSEU2
Sequence: MTESVLDYMTRLGRAAREASRVIGRASTAQKNRALQATAAALDEARAELSAANALDLANGQANGLEPAMLERLALTPARIDGMIVGLRQVAALADPVGAIRDMSYRPSGIQVGKMRVPLGVVGIIYESRPNVTIDAASLCLKSGNATILRGGSEAIHSNRAIAACIERGLAEAGLPAAVVQVVETTDRAAVGALISMPEYVDVIVPRGGKGLIERVSRDARVPVIKHLDGICHVYVSAHADLPKAQKIAFNAKTYRYGICGAMETLLVDQTIAADFLPSMAAQFREKGVELRGCERTRELIDVIPATEDDWHTEYLDAILSIRVVSGLDEAIEHINHYGSHHSDAIVSDHQSQVRRFMAEVDSSSVMVNAPTCFADGFEYGLGAEIGISTDKLHARGPVGLEGLTCEKYIVIGDGQLRGQA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP2_EMENI
Sequence: MSSYGGSGGYQRDSYRSGGGGGYSNGYSNGHGGGYGGRGGGYGGGGGSGYGGGYGGGGYGGGGYGRGGGGAGAGAGGDRMGNLGSGLKKQDWDLDTLPKFEKSFYKEHPDVTARSQREVDEFRKKCEMTVQGRDVPRPVETFDEAGFPQYVLSEVKAQGFEKPTAIQSQGWPMALSGRDVVGIAETGSGKTLSYCLPAIVHINAQPLLAPGDGPIVLILAPTRELAVQIQAEISKFGKSSRIRNTCVYGGVPKGPQIRDLSRGVEVCIATPGRLIDMLEAGRTNLRRVTYLVLDEADRMLDMGFEPQIRKIISQIRPDRQTCMWSATWPKEVRQLASDFLNNYIQVNIGSMDLSANHRITQIVEVISEFEKRDRMIKHLEKIMENRGNKCLVFTGTKRIADEITRFLRQDGWPALSIHGDKQQQERDWVLNEFKTGKSPIMVATDVASRGIDVRDITHVINYDYPNNSEDYVHRIGRTGRAGAKGTAITFFTTDNAKQARDLVTILSEAKQQIDPRLAEMVRYSGGGGHGGGYGRWGGRGGGRGRGGNFTASNAAPLGNNRRW
What is the function of this protein?
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
What are the official names of this protein?
ATP-dependent RNA helicase dbp2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FABA_CELJU
Sequence: MTSFQPQSSYSRDDLIECGKGNLFGPGNAQLPLPNMLMLDRITHISHTGGEFGKGEIIAELDISPDLWFFECHFPGDPVMPGCLGLDAMWQLVGFFLGWKGNLGRGRALGCGELKFTGQILPTAKKITYHIHLKRVIERKLIMGIADGRVSCDGKDIYFAHDLRVGLFQNTDSF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRA_PHOLL
Sequence: MIKIKKGLDLPIAGAPAQVIEDGPTIRHVALLGEEYVGMRPSMLVKEGEHVKKGQILFEDKKNPGVVFTSPACGQVVAINRGEQRILQSIVIEITGDEQVNFDRYDRAQFTQLSREQVEKNLIDSGLWTALRTRPYSRSPAPGSSPKAIFVTAMDTQPLAANSQVIIATDKEAFVDGLNVLTKLTEGKVHVCHSAGSLPNVGNNAQITYNQFSGPHPAGLAGTHIHFIEPVSATKTVWHLGYQDVIAIGKLFTTGTLYTDRVIALAGPQVEKPRLIRTCLGADLLELTQGQLKQGENRIISGSVLCGTQSDEVHHYLGRFHTLVSVLREGREKELFGWIMPGIDKFSITRTTIGHFLKNKRFAFSTTMNGGERSMVPIGNYERVMPLDIMATHLLRDLLAGDTDSAQALGCLELDEEDLALCTYVCPGKYEYGPVLREVLTKIEQEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: VKT28_DRYCN
Sequence: MSSGGLLLLLGLLTLWAELTPVSSKDRPHFCHLPADTGPCKARFQAFYYHPVHRKCLEFIYGGCEGNANNFKTIDECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor 28, SPI-28.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCFP_ECOHS
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQSHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: YIA4_MYCBO
Sequence: MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASAFFAAELDRPAR
What are the official names of this protein?
Insertion element IS6110 uncharacterized 12.0 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: CH10_LACP7
Sequence: MKLVPLGDKVVLKQLVAEETTKSGIVLPGQAKEKPQQAEVVAVGPGGMVDGKEVTMQVKVGDKVIYSKYAGTEVKLDEEEFIVVKQNDIVAIVAD
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_THEAB
Sequence: MIINESYLNVADNSGAKLLRVIRVMGGSRRKWGTVGDVVVCSVRDAVPNGDLKKGDVVKAVIVRTKKEIRRPDGTYIRFDDNAAVVLDKYNEPKGTRVFGPVAKELREKGFMKIVSLAPEVF
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: UREE_PSEP1
Sequence: MIVLSRRISEPGTRVVSGTVTLDVDSRIKSRLRVTLDDGREAGLMLERGHLLRGGELLADAEGTQLIRVLAAPEAVSTVRCADPHLLARAAYHLGNRHVPLQIEPGLLRFQHDHVLDDMLRGLGLTVEAEQAPFEPEAGAYQSAPHGHSHSHAHGHDHPFVRLPAHS
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAK_STAAS
Sequence: MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASYFEPTGPYLMVNVTGVDGKGNELLSPHYVEFPIKPGTTLTKEKIEYYVEWALDATAYKEFRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVVIEKK
What is the function of this protein?
Potent plasminogen activator that converts plasminogen into plasmin.  It forms a 1:1 complex with plasmin, which in turn activates other plasminogen molecules (By similarity).
What are the official names of this protein?
Staphylokinase.
What is the protein family that this protein belongs to?
Belongs to the staphylokinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: LYTH_STAEQ
Sequence: MKKIDSWLTKHGLKNRLTLVVIVIFIIFLILLFMFVNLSDEDTGQITITENAELRTGPNAAYPVIYKIEKGESFKKIDRKGKWIEVQNHAGTEKGWVAGWHTNLNIPADQSLSSNPLKGKTIVLDPGHGGSDQGASSSTPSKSLEKNYTLKTAKELKKLLNKEGAHVKMTRSNDKYVSLDDRNIKGDAFISIHNDALDSSNANGVTVYWFKDKQETLAQTLNSAIQKKALLTNRGSRQQNYQVLRQTDIPAVLLELGYISNPTDESMINDQLHRQVVEQAIVDGLKQYFSS
What is the function of this protein?
Probably involved in cell-wall metabolism.
What are the official names of this protein?
Probable cell wall amidase LytH.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU3_PELUB
Sequence: MIKIKKRKILLLPGDGIGPEVIQEVKKVILWLNSNKSLDFEIDEDLAGGCSYDKHGTPITDEVFYKALESEFVMLGAVGGPKWDNLEFSKKPERALLKLRKELKLFANLRPAICFEQLVDASTLKPEIVSGLDIMIVRELTGGIYFGEPRGIKPIENGERKGINTHSYTTSEIVRVAKVAFDLARKRSNRVTSCEKSNVMEAGQLWKEEVQELHDKEYKDVELSHMLADNCAMQLLKNPKQFDVIVTDNLFGDMLSDQASMLTGSLGLLPSASLGAKNKDGEMRAMYEPIHGSAPDIAGKEIANPIASILSFAMALRYSLDLDSEADALEKAVQDVLNDGLRTKDILSQGKKEVSTSAMGDAIISKLQ
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOY_STRPG
Sequence: MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVEDNTYYNVEFIELLSDKHLDYEKETGVFELTEF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: PAL4F_HUMAN
Sequence: MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A-like 4F, PPIase A-like 4F.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_SHESW
Sequence: MTKSELIEKLATRQSQLSAKEVESAIKEMLEQMATTLESGDRIEIRGFGSFSLHYRAPRTGRNPKTGSSVELEGKYVPHFKPGKELRERVDAVNV
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: DEF1_LODEL
Sequence: MSTTQRKSFKNQLKRFNNETSGSTNSTNSNASPELTSLTEMFPDWESDELNSLLQEKRNSLEVVIDLIVNNKVSKWEPIKKEKKEKKVKDDTDGFQANNTTSSTHLGSQSGKPFNKFKSSNKPPRKQGNVTKKPIKSTSDNNKPTTSTSNGAEKSKESSASGSWASALGEDTAKPATSKNTKPTTELEKAPEQDSNKDETPLESEQKQQEPQEQAEQKPKTTASATTTSEPAPKPVLKEAVIPSLNQGSWASAITPKTKPKPKPKAVKTAPSPTQATEPAQQQQQQQQSEQSEQSEQPEQPQTSQADQNESVSKPEEPVVSESQTSAQEKTLEIQEPVASAAAPAAQAPASSSSAVEAGAQGPQVVLPTSLQGVNSVGISFGSLSLGEEEPKDSHKDLREQFDQTQQKYEQPQEQPQPQQQQQQQAQAPAPSQQQQQQQQRYDLYEQQPQQSTNYQQQPQQPQQSQQSQQPQQQGQGQFGKHASQQSVPSQGQVPQQSQPTQQQYDYYSQFQQQQYPQQAGQPGAQFGGYPAYDYSAFNQQAYAASPANAHAATTGSAAAYNQYAQQSVGAADSTQSPVSAQNVLQQQQAQQQQQQIPTPFGYPYYNYYYNNPYFGGAGGLGNNGFASANTGSIGQQTQQGAQQASQQLNVPSATQPSGVSANGFGAQQQYYNPNQYSNRYPGYSYPPQPQQQQQPGQQQHQQQPGQHAGQSATGSESDAAQQGQGQGQGQQSHPQSGAPQQPVVPQYGAYQQYPQYGYQDTTQYRGGWY
What is the function of this protein?
Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled repair (TCR) factor RAD26 fails to efficiently displace stalled RNA polymerase II.  Also involved in telomere length regulation.  Binds DNA.
What are the official names of this protein?
RNA polymerase II degradation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEF1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: CNO6L_DANRE
Sequence: MPKEKYDPPDPRRLYTIMSAEEVASGKKSHWTELEISGRVRSLSSSLWTLTHLTALHINNNNLSRIPPEIAKLPHLVYLNLSSNKLRSLPAELGNMVTLRELLLNNNCLRVLPYELGRLFQLQTLGLKGNPLSQDILNLYQEPDGTRKLLNYMLDNLAVHPEQLPQRPWITLRERDQMMPTAVFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEITNCDADIISLQEVETEQYYTFFLETLKDRGYDGFFCPKSRAKLVSEQERKHVDGCGVFFKTEKFALVQKHTVEFNQVAMANSEGSEVMLNRVMTKDNIGVAVLLEVKKDLFATGLKPPPEKQLLLVANAHMHWDPEYSDVKLIQTMMFLSELKSIAERASGSINSSSPTSETSSIPIVLCADLNSLPDSGVVEYLSNGGVAENHKDFKELRYSDCLTNFSCNGKNGKPDGSITHSFQLKSAYEGNLMPYTNYTYDFKGVIDYIFFSKTHMSVLGVLGPLETQWLKDNNITGCPHPHIPSDHFSLLAQLEYHPPLPPLNGLHLPVHSTACESKMLTE
What is the function of this protein?
Poly(A) nuclease with 3'-5' RNase activity.  Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 6-like.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: CYF_PINKO
Sequence: MQNRNTYEWTKKMTRLISVLVMIHIITRTSISNAYPIFAQQGYENPREATGRIVCANCHLAKKPVDIEVPQSVLPNTVFEAIVKIPYDTQMKQVLANGKKGALNVGAVLILPEGFELAPPDRISPEIRQKTGNLYFQNYRPNQKNIIVIGPVPGQKYSELVFPILSPDPATDKEAHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYSASATGRVSKILRKEKGGYEITIDNKSDGGQVVDIVPPGPELLISEGELIKVDQPLTNNPNMGGFGQGDAEIVLQDPLRVKGLLLFLASVILAQIFLVLKKKQFEKVQLAEMNL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MUTS_RICM5
Sequence: MMLLNMNLQELKQKYNYDVATKMMQQYLDIKFAHLDCLLLFRMGDFYEMFYEDAILASNVLGIALTKRGKNGEEEIAMCGVPYHALENYLTKLIEENYKVAICDQLETPEEAKNRGGYKAVVTRDVTRIITPGTIIEENLIASAEPNYLASLVIPKNKETASLCYVDLSTSEIVVVNVPETEILNELARLKPREILLSENLRSSNLADSIFKQLNFRITYQVDSFFAINKCEKIILDFYKMKDIKGIGEISSSQICAIGSVLEYLSLTQKQNIPHLPIPRIINFHSYMTIDFSTRRNLEIVTNSQGGSQGSLLSTLNHTVTKQGGRLLYNFLSSPLTNIAKINHRLNITEFFYSNLEIVKKIRELLKKTSDIERCLTRITMNRSSGRDLLSIKYTLETATIIKGVFCDAYGVNLPDFIEKIIKPLSGDAELYNLIDETIREDAPNNLNDGGIIKHEYHPKVAQLHDLINNGKLHIDKLKDQYRKETGIDSLKISHNNVIGLFIDITAKNVNKILDPKFIHRQTTVNHVRYTTAELQKLESELVNAKTLVISLEKALYADICSQVIEKASYLRMLASSLNGLDVFCNFAYIADEYDYVKPEFTDALSFDIVKGRHPVVEKALQRESKSFVYNDCHLSELERIWLITGPNMAGKSTFLRQNAIIAIIAQIGSFVPAKSAKIGVVDKIFSRIGAADDLIKGQSTFMAEMLETSAILAQSTKNSLIILDEVGRGTSTYDGVSIAWSVLEYIHDKLKCRCLFATHYHELTVMSNFLPALQNYTIAIEESGKDILFLHNIISGAADRSYGLHVAALAGLPASVINRAKQILLKFEKTSTGKGKNILSMESNNLSLFNLEPNKTTISSKLDEKFSTIDPDKLSPKEALELIYELKKWV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RPPH_BARCL
Sequence: MDTIVDFKALPYRKCVGILVFNYEGKVWVGRRLMTVSHANVDMSKLWQLPQGGINQGEKPIDAARRELYEETGIQSVKLIKEAQDWFEYDFPQELMGHVLNNKYRGQTQKWFSFQFTGEISEITINPPPDGNKAEFDQWKWVDLEELPSIVVSFKKHVYTQVVKEFRNSFKYL
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.