PharMolix/UniProtQA huggingface dataset:
Protein: CSLC1_ORYSJ
Sequence: MARWWGGEGRGGSGTPVVVKMESPEWAISEVEAGAAAPGSPAAGGKAGRGKNARQITWVLLLKAHRAAGKLTGAASAALSVAAAARRRVAAGRTDSDDAAAAPPGESPALRARFHGFLRAFLLLSVLLLAVDVAAHAQGWHAVVPDLLAVEGLFAAAYASWLRVRLEYLAPGLQFLANACVVLFLIQSADRLILCLGCLWIKLKGIKPVPKASGGGGGGKGSDDVEAGADEFPMVLVQIPMCNEKEVYQQSIGAVCNLDWPRSNFLVQVLDDSDDAATSALIKEEVEKWQREGVRILYRHRVIRDGYKAGNLKSAMNCSYVKDYEFVVIFDADFQPQADFLKRTVPHFKGNEDVGLVQARWSFVNKDENLLTRLQNINLCFHFEVEQQVNGVFLNFFGFNGTAGVWRIKALEDSGGWMERTTVEDMDIAVRAHLKGWKFLYINDVECQCELPESYEAYRKQQHRWHSGPMQLFRLCFVDIIKSKIGVWKKFNLIFLFFLLRKLILPFYSFTLFCIILPMTMFVPEAELPAWVVCYIPATMSLLNILPAPKSFPFIVPYLLFENTMSVTKFNAMISGLFQLGSAYEWVVTKKSGRSSEGDLVSLVEKQPKQQRVGSAPNLDSLAKESHPKKDSKKKKHNRIYQKELALSFLLLTAAARSLLSVQGIHFYFLLFQGVSFLVVGLDLIGEQVE
What is the function of this protein?
Probable beta-1,4-glucan synthase rather involved in the synthesis of the xyloglucan backbone than cellulose.  Seems to work simultaneously with xyloglucan 6-xylosyltransferase.  Xyloglucan is a noncellulosic polysaccharides of plant cell wall and consists of a glucan backbone substituted by xylose, galactose and fucose (By similarity).
What are the official names of this protein?
Probable xyloglucan glycosyltransferase 1, Cellulose synthase-like protein C1, OsCslC1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: MDV1_KLULA
Sequence: MSSNTGDQFANLGKALSTTASVLFSSQPMEDTILSYSSPYKKLLHETITNAGGGSSLVKVRHDVKLSKGKNTGFQDIYSNSKEFFKNSYSDPKTTFKVLSYLSDDLLEDAPRDTIPQNKNMITENGEKRSAKSKKQEPTLFQGFEASLPVINETIELQQKLIMNSDMKPLTDSESIPVYAEEEEQEEEFSLPDHLKADKLLHSYSASFLKDASRSITDNLDLLEIQKNLAASEIRELDIKLEKLKMMRELVFKRVAKIEQHELFLEKHLNNVKDRIDMIIEYNMDKEYSSEDEENINGLSELSPKTGETNETYETAATTPLENKEEEHSPLLSKSIYQQLQDHEKKSDISERKKHSTSKKIKDVGVSHRNRRRKTYPTLQQFYDSGSKITSLPKAHDEDITCLDFDMPFGTMCSAGSLDHSVKVWDLSKKKQIATLHGHLASISCMQIDQYSTLITGGRDAVLKLWDIDKAMADEASNSSEDNDACLYTFDSHVDEITAISFDGDNLVSGSQDRTVRQWDLNSGKCTQTIDISFATGPMRSQRNIPLRNSVLLTKEPPAIGALQCFDAALATGTKDGIVRLWDLRSGKVVRMLEGHTDAITSLQFDSVNLVTGAMDRSIRIWDLRTGILSDVFAYEQPITSLHFDLDKIVISNNEPTVKIYNRKDGNHWFCGEDDPEQGNVDFVRYKHGYLVEGRSNGDINTWAI
What is the function of this protein?
Involved in mitochondrial fission.  Acts as an adapter protein required to form mitochondrial fission complexes.  Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity).
What are the official names of this protein?
Mitochondrial division protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MDV1/CAF4 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EIF3H_EMENI
Sequence: MAEKEVTPLTAVKVEALVVMKIIKHCSQVFPTTATGSIVGMDVDGVLEITNTFPFPVVEVPPESHFDNAAPNPAAAAPRAKANTVYQAEMIRMLREVNVDANNVGWYTSANMGNFVNMNVIENQFFYQKEMNERTVALVHDPSRSAQGSLSLRAFRLSPKFMAAFKDNKFTSDELQKSNLKYQDILVELPVEIHNSHLITSFIHQLQNQTQATPAEIPTSLATLESSPFAKQTILAPNFDNLSLSIDPFLEKNCDLLLDSIETHHTETSNFQYYQRSLAREQAKITAWQAKRKAENATRATLKQPPLPEDEWQRLFKLPQEPSRLDSMLNSRQVEQYARQIDSFVSSTTGKMFAVKGNLLPSEIAK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKT3L_BUNMU
Sequence: MSSGGLLLLLGLLTLWAELTPVSSRKRHQFCNVPPEPGRCNANVRAFYYNPRLRKCIEFSYGGCGGNANNFKSRGECKRTCAE
What is the function of this protein?
Binds and inhibits MMP-2 and shows an activity in inhibiting migration and invasion of neuroblastoma.  Intact C-terminus is crucial to the activities of this protein (PubMed:19706303).
What are the official names of this protein?
Kunitz-type serine protease inhibitor PILP-3, Protease inhibitor-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: PHF1_HUMAN
Sequence: MAQPPRLSRSGASSLWDPASPAPTSGPRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLWKDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPAPGEGEGTSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFTSENWDSLLLGELSDTPKGERSSRLLSALNSHKDRFISGREIKKRKCLFGLHARMPPPVEPPTGDGALTSFPSGQGPGGGVSRPLGKRRRPEPEPLRRRQKGKVEELGPPSAVRNQPEPQEQRERAHLQRALQASVSPPSPSPNQSYQGSSGYNFRPTDARCLPSSPIRMFASFHPSASTAGTSGDSGPPDRSPLELHIGFPTDIPKSAPHSMTASSSSVSSPSPGLPRRSAPPSPLCRSLSPGTGGGVRGGVGYLSRGDPVRVLARRVRPDGSVQYLVEWGGGGIF
What is the function of this protein?
Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex.  Involved in DNA damage response and is recruited at double-strand breaks (DSBs).  Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex: it is however unclear whether recruitment of the PRC2 complex to H3K36me3 leads to enhance or inhibit H3K27me3 methylation mediated by the PRC2 complex.  According to some reports, PRC2 recruitment by PHF1 promotes H3K27me3 and subsequent gene silencing by inducing spreading of PRC2 and H3K27me3 into H3K36me3 loci (PubMed:18285464, PubMed:23273982).  According to another report, PHF1 recruits the PRC2 complex at double-strand breaks (DSBs) and inhibits the activity of PRC2 (PubMed:23142980).  Regulates p53/TP53 stability and prolonges its turnover: may act by specifically binding to a methylated from of p53/TP53.
What are the official names of this protein?
PHD finger protein 1, Protein PHF1, hPHF1, Polycomb-like protein 1, hPCl1.
What is the protein family that this protein belongs to?
Belongs to the Polycomblike family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes specifically to the promoters of numerous target genes. Localizes to double-strand breaks (DSBs) sites following DNA damage. Co-localizes with NEK6 in the centrosome.
Protein: RUTC_SERP5
Sequence: MPKTIITPPGTGKPLAPFVPGTLADGVVYVSGTLAFDKNNNVVHVGDAAAQTRHVLETIKSVIETAGGCMDDVTFNSIFLTDWQNYAAINQVYAEYFPGDKPARYCIQCGLVKPDALIEIATVAHIGR
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: MCP5A_MACPC
Sequence: MGFEDGFYTIRHLVEGQPPNIPGGMYASSKDGKDEPVTAEPLGPHSKIRWWIARYPEAGEDMYTITEFRVDESIPGQWARPHNEVGGPVYLYDRIRAEETGYVCEWRIQPAYEDVDGVFNIMGNSRIGSTDWADLREEGGKPQVYLKPVPVVPNMYIPRWFISKVD
What is the function of this protein?
Inhibits papain and cysteine cathepsin endopeptidases, and also inhibits cathepsins B and H, which exhibit both exopeptidase and endopeptidase activities.
What are the official names of this protein?
Macrocypin-5a.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I85 family.
Protein: YPI9_CLOPF
Sequence: MIWSKLSSSINYYINKRIWGEELLKENILLLNQYIEDAFILEDGIYKYLDKKTYEYIDLSEEDMKKIEEAFIERLEKKRKVNKDKENFKNHMIMITEYLENEKSKEKSNVIELKNYRK
What are the official names of this protein?
Putative uncharacterized protein ORF9.
Protein: ZSA5C_HUMAN
Sequence: MAANCTSSWSLGESCNSPGSEPPQSMPSPATQLGNHDSDPETCHVNFRMFSCPKESDPIQALRKLTELCHLWLRPDLHTKEQILDMLVMEQFMISMPQELQVLVMMNGVQSCKDLEDLLRNNRRPKKWSVVSFLGKEYLMQESDVEMAEAPASVRDDPRHVSSQRTSSVNQMCPEEGQASQELQTLPRVPALFRRQEEDFLLPETTVMKGDPKALRPKPTLEKDLEEDREENPGLTSPEPQLPNSPTGVVGAKEGKEPQKRASVENVDADTPSACVVEREASTHSGSRGDALNLRGLKRSKPDATSISQEEPQGEATPVGNRESPGQAEINPVHSPGPAGPVSHPSGQEVKELLPFACEVCGKRFKYRGKLAVHTRSHTGERLFQCNLCGKRFMQRIGLQFHQRTHTGERPYTCDICQKQFTQKSYLKCHKRSHTGEKPFECKDCKKVFTYKANLKEHQRIHSGEKPHKCSKCPRAFGRPATLRRHQKTHREATSQ
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 5C, Zinc finger and SCAN domain-containing protein 5C pseudogene.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR11_NEOYE
Sequence: MARQIKKSGARKTKRNAVNGITHIKSTFNNTIVTITNLKGETLSWSSSGASGFKGAKKGTPFAAQTAAEKAARQAMDQGMRQTEVLVNGPGAGRETAIRALQAAGLEITLIKDITPVPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRF_CHRVO
Sequence: MNPLIAQGESRTTSPVVVALDFADADGALAFASRLDPAECRLKVGKELFTSSGRHLVESLAARGFQVFLDMKFHDIPNTVAQACKAAAESGVWMVNVHASGGRRMMEAAREALAGYSQRPLLIAVTVLTSMEASDLAEVGIAATPQEHVLRLATLTRDCGLDGVVCSAQEAAMLKLALGRDFKLVTPGIRLADSAGDDQRRVMTPTAALAAGSDYLVIGRPITRAADPLAALRAINQDISVFLGKQS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: FTSA_ECOLI
Sequence: MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHLITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDIAVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVLTGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLNGEAEVEKRVTASVGSWIKRLNSWLRKEF
What is the function of this protein?
Essential cell division protein that assists in the assembly of the Z ring (PubMed:11847116).  May serve as the principal membrane anchor for the Z ring (PubMed:15752196).  Also required for the recruitment to the septal ring of the downstream cell division proteins FtsK, FtsQ, FtsL, FtsI and FtsN (PubMed:9282742, PubMed:9495771, PubMed:9603865, PubMed:9882666, PubMed:10027987, PubMed:24750258).  Binds ATP (PubMed:11053380).
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner (PubMed:8955398, PubMed:8917533, PubMed:9495771). Targeted to the membrane through a conserved C-terminal amphipathic helix (PubMed:15752196).
Protein: DSBC_DICD3
Sequence: MKKRVVLFSLLTLALSGVARADDAAIKQTLNRLGLQSAEVKDSPIGGMKTVLTENGVLYITEDGKHLLQGPLYDVSGKTPVNVTNHILNERLDALKDQMIVYKAPQEKHVITVFTDITCGYCHKLHEQMKDYNALGITVRYLAYPRQGMNSQAAKDMQSIWCVADRNKAFDAAMKGDDVSPATCKTDIGAHYQLGVLFGVQGTPAIVLDDGTVVPGYQPPKEMMAMLDAHKASLKSGG
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by transferring its disulfide bond to other proteins and is reduced in the process.  DsbC is reoxidized by a yet uncharacterized protein.  Also acts as a disulfide isomerase.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbC.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbC subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: MSRB_VIBPA
Sequence: MPKIVKKEPKFVEQSGKKVTKSDEQWREQLSDEEFRVCREQGTEPPFSGKLLHNKETGVYACTCCNAPLFISDNKYDSGCGWPSFDAPLNNEAIRYLEDLSHGMVRTEIRCASCDSHLGHVFEDGPKTTGERYCVNSVSLIFNKSDE
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: DCYD_ECO81
Sequence: MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTPMAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGVTVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLARLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: YIDC_CITK8
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQTQQTTQTTTTAAGSAADQGVPASGQGKLITVKTDVLDLTINTRGGDVEQALLPTYPKELGSKEPFQLLETTPQFIYQAQSGLTGRDGPDNPANGPRPLYSVDNDTFVLADGQNELHVPMTWTDAAGNTFTKTFVLKRGEYAVNVNYSVQNAGEKPLEISTFGQLKQSINLPSHRDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNVSSNGGWVAMLQQYFATAWIPRNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMTSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFLGNWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKSS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NADB_SALTI
Sequence: MMTTPELSCDVLIIGSGAAGLSLALRLAEKHKVIVLSKGPVSEGSTFYAQGGIAAVFDETDSIASHVEDTLIAGAGICDRHAVEFVASNARTCVQWLIDQGVLFDTHVQPNGKESYHLTREGGHSHRRILHAADATGKEVETTLVSRAQNHPNIQVLERSNAVDLIISDKIGLPGPRRVVGAWIWNRNKEWVETCHAKSVVLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGSRFMPDVDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPDDFVRQHFPMIYAKLLDLGMDLTKEPIPIVPAAHYTCGGVVVDDYGRTDVDGLYAIGEVSYTGLHGANRMASNSLLECLVYGWSAAMDIDRRMPSVHSVDVLPAWDESRVENADERVVIQHNWHELRLLMWDYVGIVRTTKRLERALRRITMLQQEIDEYYANFRVSNNLLELRNLVQVAELIVRCAMMRKESRGLHFTLDYPQQLAESGPSILSPLTPHINR
What is the function of this protein?
Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
What are the official names of this protein?
L-aspartate oxidase, LASPO, Quinolinate synthase B.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERG12_SCHPO
Sequence: MSKSLIVSSPGKTILFGEHAVVYGATALAAAVSLRSYCKLQTTNNNEIVIVMSDIGTERRWNLQSLPWQHVTVENVQHPASSPNLDLLQGLGELLKNEENGLIHSAMLCTLYLFTSLSSPSQGCTLTISSQVPLGAGLGSSATISVVVATSLLLAFGNIEPPSSNSLQNNKALALIEAWSFLGECCIHGTPSGIDNAVATNGGLIAFRKATAHQSAMKEFLKPKDTLSVMITDTKQPKSTKKLVQGVFELKERLPTVIDSIIDAIDGISKSAVLALTSESDKNSSAKKLGEFIVLNQKLLECLGVSHYSIDRVLQATKSIGWTKLTGAGGGGCTITLLTPECKEEEFKLCKESLLAHKNSIYDVQLGGPGVSVVTDSDSFFPQYESDFDFKKLNLLSKFNKYYI
What is the function of this protein?
Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (By similarity).  Erg12 converts mevalonate into 5-phosphomevalonate (By similarity).  The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.  Activity by the mevalonate kinase erg12 first converts mevalonate into 5-phosphomevalonate.  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase erg8.  The diphosphomevalonate decarboxylase mvd1 then produces isopentenyl diphosphate.  The isopentenyl-diphosphate delta-isomerase idi1 then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).  Finally the farnesyl diphosphate synthase fps1 catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (Probable).
What are the official names of this protein?
Mevalonate kinase, MK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FABP5_RAT
Sequence: MASLKDLEGKWRLVESHGFEDYMKELGVGLALRKMGAMAKPDCIITLDGNNLTVKTESTVKTTVFSCTLGEKFDETTADGRKTETVCTFTDGALVQHQKWEGKESTITRKLKDGKMVVECVMNNAICTRVYEKVQ
What is the function of this protein?
Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind.  In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors (By similarity).  Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival.  May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling.  Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity).
What are the official names of this protein?
Fatty acid-binding protein 5, Cutaneous fatty acid-binding protein, C-FABP, DA11, Epidermal-type fatty acid-binding protein, E-FABP, Fatty acid-binding protein, epidermal.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Synapse. Postsynaptic density. Secreted. Note=Localizes primarily to the cytoplasm. Upon certain ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into nucleus (By similarity). Secreted by astrocytes, but not by neurons (By similarity).
Protein: CIAO1_ASPOR
Sequence: MTENPTASLTLLSDLTPPSLERTWLTAPHPSLPIVATCSSDKTVRVYSLTNFRLLSTISGGHKRSVRTCAWKPHVQGESVLATGSFDATVGIWRRWDSYGRAEDGTDVRGLSSETLDGNGRDTQEYEDDEEWRFAVLLDGHDSEVKSVSWSPSGMLLATCSRDKSIWIWEDLDDGDNNFETVAVMQEHEGDVKCVAWHPVEECLASASYDNTIRLWREDIDDWGQVACIKGHTGTVWYLDWEGIGNVPSTAAVCEQGTSLSAEWKDQRAMSGPRLASCSDDRTVRIWKRRPKEQRAQSQVGSTGIPSIIRPTGTDETWEEDVLLPQIHELSIYAVAWSKRTGLLASVGADGRIVVYEELFLTSPARTPDTNTPTDTSAIIPRTHTEWVAIAILEGAHGIYEVNHVAWARRADRCRKENEEVLITTADDGSIKVWTLRR
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
Protein: Y733_FRATM
Sequence: MDHSVLNVLVCPICKANLYYGKENQVLVCKADKLAYPIRENIPVMLVEEAKKMTLEEVKKYG
What are the official names of this protein?
UPF0434 protein FTM_0733.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: FES1_CRYNB
Sequence: MPDINELLRWSIANSTAPDTDASEQLQIRFNPNSTQSGTSTLHASDSGPPDISPASTPGPVTPDDGSSLPLPPGTEVPVTKKEDLTTEMLDLILGKGDSITMKEKMAFATDENNSVEDRVEALDDFEMLIELIDNANNMPILKLWDPLLTLLSSSHPEIVAHTCWIIGTAIQNNIKAQAAFYIHETFSRILEIIYPPSSISSYPPSVRAKATYALSAALKHWPLASYALYTATSSAENGYSVLRRGVNDPQAIVRRKMAFLVGTLAMQSGERYEGEIPSEVRNYIEENEKNAPSESLVEGLKREGVFTALVDGLKQGVDDVEYEENAMRALVRAHQKGGLTVSEKSDLKTIWEKWGKQGRQERGLDGEDGKEVSETLSS
What is the function of this protein?
Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP.  Required for fully efficient Hsp70-mediated folding of proteins (By similarity).
What are the official names of this protein?
Hsp70 nucleotide exchange factor FES1.
What is the protein family that this protein belongs to?
Belongs to the FES1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_BURPS
Sequence: MLPTVFIVSDGTGITAETFAHSILSQFDQKFRLVRVPFIDSIEKAYDTVRKINDAAQHDGRRPIVFTTLVDGESNEIVKRSNALVLDMFQRFVEPLEQELQLKSSHAMGRVHQNADTEEYKTRIEAINFSLAHDDGQSNRNLADADVILIGVSRSGKTPTSLYLAMQYGVKAANYPLIPEDFERGKLPTPLHPHRDKLFGLSIDPMRLSEIRNERRPGSKYAAPENCRYEINEAEAMMRREGVKWLSSTHKSIEEIATTILQEIKLERQSY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: Y575_MYCPN
Sequence: MLQNLALSFPFITRFFQKQMLGSQNSSGKTPGFNEAEGITSNIFQIAGGISLLVILLLIIGFLSCLLGGIFLHKHKYAEVGSPAHAKTKNLFVAFFVVGSLLLLVAVVMLIAFGVLDASLPLPKENNS
What are the official names of this protein?
Uncharacterized protein MPN_575.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NOP9_CANAL
Sequence: MGKTKSRGRRAEKKNKKNEPGFNEDVSNLDSDVTITNQEPLSSSMSSTSGIPNTFFGLVDNNELDYFKQAESTLNINAFETDEERQGFINSVLEEAQGKELKLVTNQICSKLMERLILFANHNQLKKIFKQFQNHFVSLAFHKYASHVLETLLVRSAALIEKELTQTDEEKLEEAEEEEAEEEEAEEDSLNNDVPMEDLFISMLNEFKPHLTTMIDHSYASHVLRLLILILAGKELPSSVTSNSTLRSKKSKIARKMIEIKDNEDFDRAFQTPQSFKNELREYCQTIIVGLDTKSARELSIHKIGSPVLQLLIQVEGLVDRERSFWHLIFAKDSEGKDSVEESFVEYLLSESVGSHFLESIIKNDGARPKYIERLYKLYMKDRVLKLAKRSTTGVYIIQALLFKLKPVEVEYILDQIIPELAELISIAENQNLDLANKLIDASISRGNYRRDEIINQLFIKFAPNYDIENPSDNTSTEFIENILQLTGSTLGNTRDDWPTAEERKRALFLEKLMEYDYKFVICTWFNFMALPIERFVQMCFHGVFCHVVEKALIVEPEEPKPIQILRKRLLNIFQGQIVGLACNSYGSHIVDSLWNFTVLLPMYKDRIASELLGDSNKVKESTYGRLVWKNWGMELFVRKKYDWKALIKQQEQEYYGETEDSTEKRAKKPIELKMERLAEEKRRQEEMAERAQSGYTKRKLEEATGTASEKKQKLRGRRR
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PG049_VACCW
Sequence: MGTNGVRVFVILYLLAVCGCIEYDVDDNVHICTHTNVSHINHTSWYYNDKVIALATEDKTSGYISSFIKRVNISLTCLNISSLRYEDSGTYKGVSHLKDGVIVTTTMNISVKANIIDLTGRVRYLTRNYCEVKIRCEITSFALNGSTTPPHMILGTVDKWKYLPFPTDDYRYVGELKRYISGNPYPTESLALEISSTFNRFTIVKNLNDDEFSCYLFSQNYSFHKMLNVRNICESEWEALNNNNDNSSSMPASHNNLANDLSSMMSQLQNDNDDNNDYSAPMNVDNLIMIVLITMLSIILVIIVVIAAISMYKRSKYRHIDN
What is the function of this protein?
Plays a role in the spread of virus to neighboring cells ex vivo.
What are the official names of this protein?
Protein OPG049, 36 kDa major membrane protein F5.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG049 family.