PharMolix/UniProtQA huggingface dataset:
Protein: SUCC_LEPBJ
Sequence: MKIHEYQAKEILRRHKANVPFGIVIDKKENASKAHDEVTSKTGGSVVVVKAQIHAGGRGKGGGVKVTKTKEDATAAVDKILGMQLITPQTGPEGKKVLKVYLEQGIDIAKEYYLSILLDRSIRKTILMASTEGGMEIEEVAETHPEKILKIAVDPGIGLQVNQARQLAFELGLPAESHKSFQSLVMAIYDAYIKEDASLLEINPLILTKQNEIIAGDCKIDLDENALYRHADNAAFRDITEEDPLEVQASEFNLNYVKLDGNIGCMVNGAGLAMATMDIVKLAGAEPANFLDVGGGANKTTVTNGFKIILGDPNVKGIFVNIFGGIVRCDMVAEGIIEAAKAVDLKVPLVVRLQGTNSELGREVLNKSGLKITGVDDLREAASTIAKLIK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PSA7_RAT
Sequence: MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKICALDDNVCMAFAVVASVSGLTADARIVINRARVECQSHRLTVGDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILSPEEIEKYVAEIEKEKEENEKKKQKKAS
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).  Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions.  The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions.  Plays a role in hepatitis C virus internal ribosome entry site-mediated translation.  Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation.  Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
What are the official names of this protein?
Proteasome subunit alpha type-7, Proteasome subunit RC6-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9.
Protein: ATPF_VIBVY
Sequence: MNMNATLLGQAISFAMFVWFCMKYVWPPIMQAIEERQKKIADGLQAAERAAKDLDLAQANASSQLKEAKRTATEIIEQANKRKAQILDEAREDAQTERQKILAQAEAQLEAERNRARDELRKQVATLAVAGAEKILERSIDKDAHKDILDNITAKL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MRGX2_RHIBE
Sequence: MDPTTPAWGTESTTMNGNDQALPLLCGKETLILVLLILFIALVGLVGNAFVLWLLGFRMRRNAFSVYVLSLAGADFLFLCFPMINCLEYLINFFHSISINFPSFFTTVMTCAYLAGLSMLSAISTERCLSVLWPIWYRCRRPRHLSAVLCVLLWALSLLLSILEGKFCGLLFSDGDSGWCQTFDFITAAWLMFLFVVLCGSSLALLVRILCGSQGLPLTRLYLTILLTVLIFLLCGLPFGIQWFLILWIWKNSDVLFCHIHPVSVVLSSFNSSANPIIYFFVGSFRKQWRLRQPVLKLALQRALQDTAEVDHSEGCFSQGTLEMSGSSLV
What is the function of this protein?
Mast cell-specific receptor for basic secretagogues, i. e.  cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core.  Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium.  In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction.
What are the official names of this protein?
Mas-related G-protein coupled receptor member X2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAA7G_RAT
Sequence: MATDDGSFPWTQESILSRDLLSALSPQLCYENLNRSCVRSPYSPGSRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADLLVGLTVMPFSMVRSVEGCWYFGDSYCKLHSCFDISFCSSSLLHLCFISVDRHIAVSDPLIYPTRFTASVSGKYITFSWLLSIIYGFSLIYTGASEAGLEDLVSALTCVGGCQVAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNMEKMSKQTARASDSYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFVDSIIDAFLGFITPTYVYEILAWIAYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILKENSSTINLFPE
What is the function of this protein?
Orphan receptor.  Could be a receptor for trace amines.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.
What are the official names of this protein?
Trace amine-associated receptor 7g, TaR-7g, Trace amine receptor 7g, Trace amine receptor 9, TaR-9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PCKA_ECOSE
Sequence: MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHLKGLVTKQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEELAGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQEKAETLAKLFIDNFDKYTDTPAGAALVAAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_AETCO
Sequence: MPIGVPKVPFRSPGEGDTSWVDIYNRLYRERLFFLGQEVDTDISNQLISLMIYLSIEKDTKDLYLFINSPGGWVISGMAIYDTMQFVRPDVQTICMGLAASIASFILVGGAITKRIAFPHARVMIHQPASSFYEAQTGEFILEAEELLKLRETITRVYVQRTGKPIWVVSEDMERDVFMSATEAQAHGIVDLVAVQ
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ODC_NICGU
Sequence: MAGQTIIVSGLNPAAILQSTIGGGASPTAAAAENGTRKVIPLSRDALQDFMLSIITQKLQDEKQPFYVLDLGEVVSLMDQWKSSLPNIRPFYAVKCNPEPSFLSILSAMGSNFDCASRAEIEYVLALGISPDRIVFANPCKPESDIIFAAKVGVNLTTYDSEDEVYKIRKHHPKSELLPRIKPMFDGNARCPMGPKYGALPEEVEPLLRAAQAARLTVSGVSFHIGSGDADSNAYLGAIAAAKEVFETAAKLGMSKMTVLDVGGGFTSGHQFTTAAVAVKSALKQHFDDEPELTIIAEPGRFFAETAFTLATTVIGKRVRGELREYWINDGLYGSMNCVLYDHATVNATPLAVLSNRTNVTCGGSKTFPTTVFGPTCDALDTVLRDYQLPELQVNDWLVFPNMGAYTKAAGSNFNGFNTSTIVTHLAYTYPS
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (By similarity).  Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine (PubMed:11736657).  Can also use, with a lower efficiency, L-lysine as substrate to produce cadaverine (PubMed:11736657).  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis (By similarity).
What are the official names of this protein?
Ornithine decarboxylase, chloroplastic, Lysine decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PLSX_STAAC
Sequence: MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNHDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: DADA_BURM7
Sequence: MRVVILGSGVVGVASAYYLARAGHEVTVIDREAGPALDTSFANAGQISPGYAAPWAAPGVPLKAVKWMFEKHAPLAIRLDGTRFQLQWMWQMLRNCTTERYALNKGRMVRLAEYSRDCLQALRAETAIQYEGRTGGTLQVFRTQQQLDGAAKDIAVLREANVPFELLSSDELKKAEPALAAVSHKLTGGLRLPGDETGDCQLFTTRLAALAEQLGVKFRFNTRIDALAVAGGKIAGVQCGGEMVRADAYVVALGSYSTNLVASLVKIPVYPLKGYSITAPIVDAAKAPVSTVLDETYKIAITRFDDRIRVGGMAEIVGFDKRLRDARRGTLEMCVNDLFPGGGDTAKATFWTGLRPMTPDGTPIVGRTPVPNLFLNTGHGTLGWTMSCGSGQLLADLMSGKKPAIRADDLSVHRYLSETDGEHRPAYA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: LUXS_STRR6
Sequence: MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: YA2_MDBVW
Sequence: MTQPVLYKYSVIQFPGSFDSSVHNSYVCIPNSWIINRDEKKVIVAVPSNEEVPVSMSCILNNGPPSSHWKTYAGTLKYETGKSKILFTFFKCSYQLYKILIVIDSLQLTDPSNFIPQEMMSPTIQ
What are the official names of this protein?
Uncharacterized protein A2.
Protein: MIAA_ACICJ
Sequence: MTQSPRACSAPPARPLLIVAGPTASGKSALALAAAQRFGGTIINADAMQCYADWRIITARPTPADEAAAPHRLYGVRRLEEAVDAAWWRGRALAELAAAELPILCGGTGMYLSSLVNGIAPIPDPGPNARAEARRMLAADGPAALHAWLAARDPATATKLRPSDPQRLARAAEVLLGTGRGLAAWHAAPRAGLAGYRVMLLLLDPPRPALREAIAARFEAMLAAGALAEVAAVAARAPDPALPGLRAHGVPELLAHLAGAISLDEAASRAIAATAAYTKRQATWFRHQKLADQRNTHTIRSRLTDSTQFSESTVRSIISFINLSS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SCXS_TITPA
Sequence: NKDGYLMEHDGCKLSCLMKKGTFCAEXCARLXGXDGYC
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Putative beta-neurotoxin.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y183_HELPH
Sequence: MLEKLIERVLFATRWLLAPLCIAMSLVLVVLGYVFMKELWHMLSHLDTISETDLVLSALGLVDLLFMAGLVLMVLLASYESFVSKLDKVDASEITWLKHTDFNALKLKVSLSIVAISAIFLLKRYMSLEDVLSSIPKDTPLSHNPIFWQVVIHLVFVCSALLAAVTNNIAFSQNKGH
What are the official names of this protein?
UPF0114 protein HPAG1_0183.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAA_STRT2
Sequence: MKTKLIVVAGPTAVGKTALGIELAERFNGEIISGDSQQVYRQLNIGTAKATPEEQAAAVHHLIDVRDVDESYSAYDFVTEAQAAITDIVSRGKLPIIVGGTGLYLQSLLEGYHLGGKVDQNQVLAYRSELEQLSDQQLFEKIDSLGIEIKEINRRRAIRALELYRFSDNLENTETCYEPFIIGLDDERSLIYDRINTRVDKMVELGLLEEAKWLYDNFPEAQSARGIGYKELFPYFSGEQTLDEALEKLKQNTRRFAKRQLTWFRNRMTVSFYQISSPEYPENVIQDLAIFLNEEEGEK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SECA_BACFN
Sequence: MGFNEFLSSIFGNKSTRDMKEIQPWVDKIKAAYPEVAKLDNDGLRAKTEELKEYIRNSASKERAKADELRAGIENVELEDREEVFAQIDKIEKEILEIYEKALDEVLPVAFSIVKESAKRFSENEEIVVTATDFDRKLAATKDFVRIEGDKAIWQNHWNAGGNDTVWNMVHYDVQLFGGVVLHKGKIAEMATGEGKTLVATLPVFLNALTGNGVHVVTVNDYLAKRDSEWMGPLYMFHGLSVDCIDRHQPNSDARRQAYLADITFGTNNEFGFDYLRDNMAISPKDLVQRQHNYAIVDEVDSVLIDDARTPLIISGPVPKGEDQLFDQLRPLVERLVEAQKVLATKYLSEAKKLINSDDKKEVEEGFLALFRSHKALPKNKALIKFLSEQGIKAGMLKTEEIYMEQNNKRMHEATDPLYFVIDEKLNSVDLTDKGVDLITGNSEDPTLFVLPDIAAQLSELENEHGLSDEQKLEKKDALLTNYAIKSERVHTINQLLKAYTMFEKDDEYVVIDGQVKIVDEQTGRIMEGRRYSDGLHQAIEAKEGVKVEAATQTFATITLQNYFRMYHKLSGMTGTAETEAGELWDIYKLDVVVIPTNRPIARKDMNDRVYKTKREKYKAVIEEIEQLVQAGRPVLVGTTSVEISEMLSKMLTMRKIEHNVLNAKLHQKEADIVAKAGLSGTVTIATNMAGRGTDIKLSPEVKAAGGLAIIGTERHESRRVDRQLRGRAGRQGDPGSSVFFVSLEDDLMRLFSSDRIASVMDKLGFQEGEMIEHKMISNSIERAQKKVEENNFGIRKRLLEYDDVMNKQRTVVYTKRRHALMGERIGMDIVNMIWDRCAAAIENNADYEECKLDLLQTLAMEAPFTEEEFRNEKKDKLADKTFDVAMANFKRKTERLAQIANPVIKQVYENQGHMYENILIPITDGKRMYNISCNLKAAYESESKEVVKSFEKSILLHVIDESWKENLRELDELKHSVQNASYEQKDPLLIYKLESVTLFDNMVNKINNQTVSILMRGQIPVAEPTEEQQEAARRVEVRQAAPEQRQDMSKYREQKQDLNDPNQQAAAQQDTREAVKREPIRAEKTVGRNDPCPCGSGKKYKNCHGRNS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: HUTI_XENTR
Sequence: MACKFRLLLENAEQIVVVCSKEEEYLLEDGMQHLAILEKASLVIGNDGFIKDVGPAETIRNQFSNASFENIIDCSGKCVLPGFVDAHTHPVWAGDRVHEFAMKLAGATYMDIHKAGGGINYTVEHTTTASEEELFCSFKHRLERMLRAGTTLVECKSGYGLKLETELKMLRVIERAHQELDIAVSSTYCGAHSVPKGKSAQEATDDIIANHLPALKQMALNGEIHVDNIDVFCEKGVFDLDSTRKILQAGKAIGLNLNFHGDELNPMNSAELGAELGAHAVSHLEEVSDKGIAALAKAKCSAVLLPTTAYILRLKQPRARDMLKAGVIVSLGSDFNPNAYCFSMPMVMHLACVNMKMSLKEALAAATINAAYALGRAHTHGSLEVGKQGDVVVINASRWEHVIYQFGGHQELIEYVVIKGKIVYKNENVLCL
What are the official names of this protein?
Probable imidazolonepropionase, Amidohydrolase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
Protein: LEG3_HUMAN
Sequence: MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
What is the function of this protein?
Galactose-specific lectin which binds IgE.  May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration.  Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity).  In the nucleus: acts as a pre-mRNA splicing factor.  Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.  Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
What are the official names of this protein?
Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=Secreted by a non- classical secretory pathway and associates with the cell surface. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059).
Protein: COAD_BACTN
Sequence: MRKAIFPGTFDPFTIGHYSVVERALTFMDEIIIGIGINENKNTYFPIEKREEMIRNLYKDNPRIKVMSYDCLTIDFAQQVEAQFIVRGIRTVKDFEYEETIADINRKLAGIETILLFTEPELTCVSSTIVRELLTYNKDISQFIPEGMEIN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IR01_HCMVA
Sequence: MPATDTNSTHTTPLHPDAQHTLPLHHSNTQPHVQTSDKHADEEHRTQMELDAADYAACAQARQHLYDQTQPLLLAYPNTNPQDSAHFPTENQHQLTHPLHNIGEGAALGYPVPRAEIRRGGGDWADSASDFDADCWCMWGRFGTMGRQPVVTLLLARQRDGLADWNVVRCRGTGFRAHDSEDGVSVWRQHLVFLLGGHGRRVQLERPSAGEAQARGLLPRIRITPISTSPRRKPPHPATSTASHHPHASPRSDHTLFPVPSTPSATVHNPRNYAVQLHAETTRTWRWAQRGERGAWMPAETFTCPKDKRPW
What are the official names of this protein?
Uncharacterized protein HKLF1, IRL1, TRL1.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 HKLF1 family.
Protein: RPOC2_PROMP
Sequence: MTSSKPKKSSRVRKTTKNSKKNHNTMMPLLPKTPPSFKNKVVDKKALKNLVSWAYKTHGTAVTAAMADNLKDLGFKYATQAAVSISVNDLKVPEAKQDLIGQAEAQITATEECYRLGEITEVERHTKVIDTWTETNERLVDAVKNNFNQNDPLNSVWMMANSGARGNMSQVRQLVGMRGLMANPQGEIIDLPIRTNFREGLTVTEYVISSYGARKGLVDTALRTADSGYLTRRLVDVAQDVIVREEDCGTERSIVINSEDGKFGSRLIGRLSAEDILDSEGNLIVPKNTAIDPSLSKTLETSLISKVNIRSPLTCEANRSVCRKCYGWALAHNHLVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVSTAESGVVRSKIKGKVEFGSKAKIRGYRTPHGVEAKQAEVDFLLKIIPTGSITNKAQKIEVTSGSLLFVEDGQDIDSDITVAQITSGAVKKSVEKATKDVICDLAGEVRYDKVIQPKEVTDRQGNITLKAQRLGRLWVLAGDVYNLPPNAKPVVSTETKVEQGTVLAEASQSSEFGGEVRLRESVGDSREVQIVTTSMLLSNFKLIEESTHSGELFHLESNDGTIYRLNTSPGSKISSGEVIADLADERFRTKTGGLVKYAPGLSVKKARSSKNGFEVSQGGTLLWIPQETHEINKDISLLMTEDMEWIEAGTEVVKDIFSQTSGIVTVTQKNDILREITVRNGSFHECEDEEILSRFTEEGKLVNPGEKIIDGVDNDEILFVQKLETSKGKGLLLRTVEEYTIPNEAELPELSHVKQEKGPSLALKAIQRLSYKDGELIKSVEGVELLKTNLSIESFDATPQMTIDVETIQDKSDKSINRLNLVILESILVRRDTISDSSHGSTHTELQINNNQLVKAGDVIATTQILCKERGVLQLPDSVEGEPIRRLIVERNEDKIKINIKDKAVVKTGDRVVDGDLISKGVKSTSCGEIEEVSSEYVILRIGRPYMVSPDSVLHVKDGDLVLRGDGLALLVFERQKTGDIVQGLPRIEELLEARRPRDSSILCKKSGVVQIKEGTDEESVSLSVIERDDSISEYQLLMGQNIMVSDGQQVTGGELLTDGPINPHDLLDCLFTDLKDQKPLMEAAQESISKLQRKMVNEVQNVYKSQGVAISDKHIEVIVRQMTSKVRIEDAGDTTLLPGELIELRQVEDTNQAMSITGGAPAEFTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFSGFVEELASEAGPHPDILAEESGGYRRTQNLRPDYTVDMPQTPIVSSTAILDDPSDEDLETTRNRHGIDPTSSNFAAFARPNAENQFSEDQLPDPAALEGLQEEGLLSDG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: RL6_RHIL3
Sequence: MSRIGKKPVQVPAGITATVDGQKVTAKGPKGELFFVANDEISLKLENNAVVVTPVNQTKDARSKWGMSRTMIEGIFKGVKDGFERKLEINGVGYRAAMQGKNLQLALGFSHDVIYEPPVGISIVVPKPTEIVVSGINKQQVGQVAAEIREYRGPEPYKGKGVKYADERIVRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: FRVR_ECOLI
Sequence: MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARIFASGSAGYQLEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLAGITRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEHSGLFLGDNAVRTLTGLIEKQHQQAQVISADNVQGLLQRVPGIASLNIIDAQLVENITGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLREQLDIPLFDSDLIGLYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLNCRVIIARSLSELVAIREEIEPLLIINNSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITADEAQRIIAREGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASILCQHPAEIIAGLTGYEAFMELLHKG
What is the function of this protein?
Could be involved in the regulation of the transcription of the FRV operon.
What are the official names of this protein?
Putative frv operon regulatory protein.