PharMolix/UniProtQA huggingface dataset:
Protein: NNRD_SCHPO
Sequence: MTSGSPKITNLLTRVKRIIPPLLDTFHKGQAGRVGVFGGCQHYTGAPYYSSMSSMLFGSDQSHIFCEKEAANVIKSYSPDLIVHPFLREKDKAGPEDSVDKCFELIKPMMGRLHAIVIGPGLGRDEWMQEIMAKVIEYARKNDMPMVIDADGLWLIQQRPELVSGYHNVILTPNVIEFKRLCDKLDIKSDGPDACNQLAGKLNLLIIQKGQSDIISDGATAYACSVPGGLKRCGGQGDILTGILATFLAWRHAYLSKEWDTEGNMDAKECLFLAAFGASACTRWCSRLAFKECGRATQSTDLVRHVGKAYNALMEDEIPSVEEKIKD
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_NEIMA
Sequence: MLTFQQIIFKLQTFWADKGCTVIQPFDMEVGAGTSHPATCLRALGPEPWFAAYVQPSRRPKDGRYGDNPNRLQHYYQFQVALKPAPANIQDLYLDSLRELGIDPKVHDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCTPVLGEITYGIERLAMYLQGVENVYDLVWAKTLDGNTVTYGDVYHQNEVEQSTYNFEYSDADWLLRQFNDYEAQAKRLLAEENAALALPAYELVLKAGHTFNLLDARGAISVTERATYIGRIRALSRAVAQKYVESREKLGFPLMKANAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_BRADU
Sequence: MASLKDMRVRIASTKATQKITKAMQMVAASKLRRAQTAAEAARPYADKMSAVISNIAGAAAGSPGAPALLAGTGRDQVHLLLVCTGERGLSGAFNSSIVRLARERALALMAQGKEVKFFCVGRKGYEQLRRQFDKQIVEHLDLRSVRQLGFVNAEDIAKKVLARFEAGEFDVCTLFYSRFRSVIAQIPTAQQIIPLVVEEGTAASTTSYEYEPEEDEILTRLLPRNLAVQIFRALLENNASFYGAQMSAMDNATRNAGEMIRKQTLVYNRTRQAQITKELIEIISGAEAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CARA_NEIMA
Sequence: MSTPALLVLADGSVFHGTSIGYEGSTSGEVVFNTSMTGYQEILTDPSYCKQIVTLTYPHIGNTGTNAEDEESRSVYAAGLIIRDLPLLHSNFRASESLHDYLVRNKTVAIADIDTRRLTTLLREKGAQGGAILTGADATIEKAQELIAAFGSMVGKDLAKEVSCTETYEWTEGEWALGKGFVTPDEQPYHVVAYDFGVKTNILRMLASRGCRLTVVPAQTSAQDVLALNPDGVFLSNGPGDPEPCTYAIEAVQKLMESGKPIFGICLGHQLISLAIGAKTLKMRFSHHGANHPVQDLDSGKVVITSQNHGFAVDADTLPANARITHKSLFDNTLQGIELTDKPVFCFQGHPEASPGPQDVGYLFDKFIGNMKAAKRA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: TERM_ADE02
Sequence: MALSVNDCARLTGQSVPTMEHFLPLRNIWNRVRDFPRASTTAAGITWMSRYIYGYHRLMLEDLAPGAPATLRWPLYRQPPPHFLVGYQYLVRTCNDYVFDSRAYSRLRYTELSQPGHQTVNWSVMANCTYTINTGAYHRFVDMDDFQSTLTQVQQAILAERVVADLALLQPMRGFGVTRMGGRGRHLRPNSAAAVAIDARDAGQEEGEEEVPVERLMQDYYKDLRRCQNEAWGMADRLRIQQAGPKDMVLLSTIRRLKTAYFNYIISSTSARNNPDRHPLPPATVLSLPCDCDWLDAFLERFSDPVDADSLRSLGGGVPTQQLLRCIVSAVSLPHGSPPPTHNRDMTGGVFQLRPRENGRAVTETMRRRRGEMIERFVDRLPVRRRRRRVPPPPPPPEEEEEGEALMEEEIEEEEAPVAFEREVRDTVAELIRLLEEELTVSARNSQFFNFAVDFYEAMERLEALGDINESTLRRWVMYFFVAEHTATTLNYLFQRLRNYAVFARHVELNLAQVVMRARDAEGGVVYSRVWNEGGLNAFSQLMARISNDLAATVERAGRGDLQEEEIEQFMAEIAYQDNSGDVQEILRQAAVNDTEIDSVELSFRFKLTGPVVFTQRRQIQEINRRVVAFASNLRAQHQLLPARGADVPLPPLPAGPEPPLPPGARPRHRF
What is the function of this protein?
Protein covalently bound to the viral DNA that acts as a primer for viral genomic replication by DNA strand displacement.  Assembles on the viral origin of replication in an initiation complex with viral polymerase, DBP, host NFIA and host POU2F1/OCT1.  During initiation, the polymerase covalently couples the first dCTP with Ser-580 of pTP.  The terminal protein stimulates the template activity over 20 fold compared to protein-free templates.  Neo-synthesized viral genomes are linked to two preterminal proteins, one for each 5' end.  These new genomes are encapsidated in the nucleus, and during capsid maturation by viral protease, preterminal protein is first cleaved into intermediary (iTP), then into mature TP.  May play a role in host nuclear matrix localization of genomic DNA.
What are the official names of this protein?
Preterminal protein, pTP, Bellett protein, Precursor terminal protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae terminal protein family.
What are the subcellular locations of this protein?
Host nucleus matrix.
Protein: AROA_AERS4
Sequence: MNSLRLEPISRVAGEVNLPGSKSVSNRALLLAALARGTTRLTNLLDSDDIRHMLAALTQLGVKYKLSADKTECTVHGLGRSFAVSAPVNLFLGNAGTAMRPLCAALCLGSGEYMLGGEPRMEERPIGHLVDALREAGAHIQYLKKDGYPPLVVDAKGLWGGDVHVDGSVSSQFLTAFLMAAPMAAGDTRIHIKGELVSKPYIDITLHIMKQFGVVIEHDNYKLFYIKGNQSYVSPGDFLVEGDASSASYFLAAGAIKGKVRVTGIGKHSIQGDIHFADVLERMGARITWGDDFIEAEQGPLHGVDMDMNHIPDAAMTIAVAALFAEGPTSIRNIYNWRVKETDRLHAMATELRKLGVEVEEGHDFITVTPPTQLKHAEIDTYNDHRIAMCFSLVALSDIAVTINDPGCTSKTFPDYFDKLASVSQAV
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_CROS8
Sequence: MKKDIHPKYVEITATCSCGNVIKTRSTVGHDLNLDVCGNCHPFFTGKQRVVDTGGRVERFNKRFSIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: SYE_POLAQ
Sequence: MAIMHIRTRFAPSPTGFIHLGNLRSALYPWAFARHNKGDFILRIEDTDLERSSQEAVDVIIEGMAWLGMDIDEGPIYQMQRIDRYRAVIKEMVEAGLAYPCYMSEDELNKLRDQQMANKEKPRYNGLWRPEPGKDLPPIPEGVLPVIRFKNPIGGSVIWNDAVKGQIEISNDELDDLVIARPDGTPTYNFCVVVDDLDMKITHVIRGDDHVNNTPRQINIMKALGGSPPVYAHLPTVLNDLGEKMSKRNGAMSVRDYQKAGYLPDAILNYLARLGWSHGDAEVFTKEQFVDWFELDSLGRSPAQHNPEKLLWLNHQYIQNADAAKLAEACKPFAHQLGIDTENGPNFIQVVGLLKDRANTLIEIAEGAKLFYATAPNLTKDQITENISEAIVPALKDLIEALKNADGTKESYSAAFKQVLAQHQIKMPALAMPVRYALFATTQTPAIDAVLVVLGKEEAINRLSKVVV
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JMJD6_DROME
Sequence: MSEEFKLPKRSRKRTREVKRKARPELDGENAWSAMRYCEKFEPFWDFTDNLERIEESQVPESEFIERFERPYKPVVIRGCTDGWLALEKWTLARLAKKYRNQKFKCGEDNEGYSVKMKMKYYVEYMQSTRDDSPLYIFDSSFGEHHRRRKLLDDYVVPKYFRDDLFQYCGENRRPPYRWFVMGPARSGTGIHIDPLGTSAWNTLIRGHKRWCLFPTQTPKELLKVTSAMGGKQRDEAITWFSTIYPRTQLPSWPEQYRPIEVLQGAGETVFVPGGWWHVVLNMDDTIAITQNFSSQTNFPCVWHKTVRGRPKLSRKWLRVLRDQRPELAQIADSINLNESTGFASDSSSNSSSSSSSSSSSSEEEESDDGGDSNTDSGQESLTAKKKKKRRMAGGGSGSGSMGGSSRS
What is the function of this protein?
Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase.
What are the official names of this protein?
Bifunctional arginine demethylase and lysyl-hydroxylase PSR.
What is the protein family that this protein belongs to?
Belongs to the JMJD6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VGLU1_BOVIN
Sequence: MEFRQEEFRKLAGRALGKLHRLLEKRQEGAETLELSADGRPVTTQTRDPPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVMQKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQIADFLRSRRIMSTTNVRKLMNCGGFGMEATLLLVVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGVFASGEKQPWAEPEEMSEEKCGFVGHDQLAGSDESEMEDEAEPPGAPPAPPPSYGATHSTVQPPRPPPPVRDY
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate.  At the synaptic vesicle membrane, mainly functions as an uniporter which transports preferentially L-glutamate but also phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells.  The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane.  In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane that affects the proton electrochemical gradient and promotes synaptic vesicles acidification.  Moreover, may function as a K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular glutamate uptake.  The vesicular K(+)/H(+) antiport activity is electroneutral.  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation.  The symporter activity is driven by an inside negative membrane potential and is electrogenic (By similarity).  Is necessary for synaptic signaling of visual-evoked responses from photoreceptors (By similarity).
What are the official names of this protein?
Vesicular glutamate transporter 1, VGluT1, Solute carrier family 17 member 7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: GLAH_PSEPG
Sequence: MNAFTQIDELVMPLPLEPQGYTIAPSKQSPRLLELTFARETVEAFVQAVAQWPVQALEYKSFLRFRVGEILDELCQGTLRPVLLNTILDRASGGMLITPVGLDDVSQAEDMVKFTTACAHLIGRSNYDAMSGQFYARFVVVNSDNSDSYLRQPHRVMELHNDGTFVNQITDYVLMLKIDEKNMEGGNSLLLHLDDWEQCDEFFRHPMARREMRWTAPPSKKVAEDVFHSVFDTDAEGRPTMRYIDQFVQPENYEEGIWLNALSDSLEGSEKKVSVPVGVGSFLLINNLFWLHGRDRFTPHEGLRRELMRQRGYVAFPKPLYQRGQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: PAND_YERPE
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLEAAGILEYEAIDIYNVDNGQRFSTYAIAAERGSRIISVNGAAARCACVGDKLIICSYVQMSYAAARLHHPKVAYFEGENQLQRKAKAVPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_ECOBW
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: MURA_WOLSU
Sequence: MDFLSITGGEKLQGSVSVSGAKNAALPLISATLLAKNEACLKNLPDVVDIKTLLSLLEMLGAKVQRIDPHTVKVNSSEILSTKATYDIVRKMRASILVLGPLLSRFGKCEVSLPGGCAIGARPVDLHLKAMEKMGAIVEIKGGYIVANAPKGLKGATIAFDKITVTGTENVVMAAALAKGVTKILNAAQEPEVVQLCEVLQAAGVEIKGIGSNELEIVGQEGEALEFKEVEVIPDRIEAGTYLCAGAMTNSSIRLERVVPEHLSAVTQKLEEIGFGIEYGENHLTLLPASKRRAFEIITTEYPGFPTDMQAQFMALATQCEGASIIEERLFENRFMHVSELQRLGAGIHLRGNTATVNGGTKLLCADVMATDLRASSALVLAALAAEGTTNIHRIYHLDRGYERLEEKLRALGAVIERGRE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSPC3_ECOLX
Sequence: MKIPEAVNHINVQNNIDLVDGKTNPNKATKALQKNILRVTNSSSSGISEKHLDHCANTVKNFLRKSIAAQSYSKMFSQGTSFKSLNLSIEAPSGARSSFRSLEHLDKVSRHYISEIIQKVHPLSSDERLLLSIIINSNFNFRHQSNSNLSNNILNIKSFDKMQSENIQTHKNTYSEDIKEISNHDFVFFGVEISNHQEKLPLNKTHHTVDFGANAYIIDHDSPYGYMTLTDHFDNAIPPVFYHEHQSFFLDNFKEVVDEVSRYVHGNQGKTDVPIFNTKDMRLGIGLHLIDFIRKSKDQGFREFCYNKNIDPVSLDRIINFVFQLEYHIPRMLSTDNFKKIKLRDISLEDAIKASNYEEINNKVTDKKMAHQALAYSLGNKKADIALYLLSKFNFTKQDVAEMEKMNNNRYCNLYDVEYLLSKDGANYKVLEYFINNGLVDVNKKFQKANSGDTMLDNAMKSKDSKMIDFLLKNGAILGKRFEI
What is the function of this protein?
ADP-riboxanase effector that inhibits host cell pyroptosis (PubMed:34671164).  Acts by mediating arginine ADP-riboxanation of host CASP4/CASP11, blocking CASP4/CASP11 autoprocessing (PubMed:34671164).  This prevents CASP4 activation and ability to recognize and cleave GSDMD, thereby inhibiting LPS-induced pyroptosis (By similarity).  ADP-riboxanation takes place in two steps: OspC3 first catalyzes ADP-ribosylation of target Arg, and then initiates a deamination to remove one N-omega group (By similarity).
What are the official names of this protein?
Arginine ADP-riboxanase OspC3.
What is the protein family that this protein belongs to?
Belongs to the OspC family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via the type III secretion system (TTSS).
Protein: SPRT_SALEP
Sequence: MKTPRLPIAIQQAVMRRLRENLAQANLKLDRHYPEPKLVYTQRGTSAGTAWLESYEIRLNPVLLLENIDTFIAEVVPHELAHLLVWKHFGRKAPHGKEWKWMMESVLGVPARRTHQFALQSVRRNTFPYHCQCQQHQLTVRRHNRVVRGEAVYRCVHCGEPLVAG
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYL1_MEDSA
Sequence: GVQRYTFDAVVSQQDTILSGLDLDCGSYLGYTSPLQGLTAFVPTS
What is the function of this protein?
A bifunctional beta-xylosidase/alpha-L-arabinosidase, exo-enzyme that acts synergistically with endohydrolases.  Releases xylose and arabinose from cell walls (By similarity).
What are the official names of this protein?
Beta-xylosidase/alpha-L-arabinofuranosidase 1, Xylan 1,4-beta-xylosidase/Alpha-L-arabinofuranosidase 1.
What is the protein family that this protein belongs to?
Belongs to the glycoside hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RISB_PSYIN
Sequence: MKIIEGGLAAPQAQIAIVISRFNSFINEQLLAGAIDTLKRTGQVADDNITVVRVPGAVELPLVAKRVAASKKFDAIIALGTVIRGGTPHFEFVAGECNKGLGQVSMDFDIPVSFGVLTTDSIEQAIERAGTKMGNKGSEAALSALEMVNVMAEFK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: Y383_MYCPN
Sequence: MKPKVQNLIFDLDGTLLSWGHEPLPQTVTFLKELQKQGFKITFATGRSHILIRNTTQFIQPDLPVISSNGALIYDFAREKALHMTQLAPQSVVPIMRLLLQLEESFCIYTDKKVFGFEKPGIPCKRLRTTQSKIVEPDITQNNFTINPLTDASKFDFATQNITKILLITEDRGRISKITKHLDAIENISYVSSMTFALDIMHKDVNKAYGLKALEQQTGLDPQMTMVFGDGDNDVEIFNAVKYSVAMANGSDLAKQNATFISEFDNDHDGIYHFLQCFLKIE
What are the official names of this protein?
Putative phosphatase MPN_383.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: RL3_SYNPW
Sequence: MSIGILGKKLGMSQLFDEQGKAVPVTLIEAGPCRITQLKTTETDGYSAVQIGFGETRDKLVNKPAKGHLAKSGEGVLRHLSEYRVDDVNGLELGGAVTVSDFEAGQKVDVSGDTMGRGFAGYQKRHGFSRGPMTHGSKNHREPGSTGAGTTPGRIYPGKRMAGRYGGKKTTTRGLTILKVDSDRNLLVVKGSVPGKPGALLNIRPANRVGAKPAKGGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PTH_BARQU
Sequence: MWLIAGLGNPGLQYQNNRHNIGFMVIDAIYQSFSFSPWSKKFQAEISNGLIDGEKTFLIKPQTFMNLSGQAIGEVLRFYKLDLKNFIVICDELDLPPGKVRVKTAGGNNGHNGIKSIDAHCGTDYCRVRLGIGHPGSKELVHQHVLGNFTKSDQEWLSPLLDAIAKNIALLIKGDRCLFMDTISQATKNKNLQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED17_ASPFU
Sequence: MADDRFTLPLRPLIEKRDRPDPLPLEIAQINAQWGSFRDVSEESLRAKIEEEKSKEYTIEEEEGEGAGAELDTTERLDQLYKRRAEIIQFAMQAHMEAMFALDFVSMLLSKHTPRQAETSMSAYLKQVAPLGSLHSEIINPPPKSEAVVRDTKTVSRGWRLQSFNAAADKLLKSASRLENEVASETRYWHEVLAVKDKGWKLCRLPRQGQTLGVQYGFLEATPIFRDRGLAALRRSEDGTLILDKGLVPTKAKTVRVRVKDCGIITGCSKPYRSAAQDPDSIEGRILQARDTLYEEELFHELFREARIMGSQGVTTRQNLVQFPVSEEQEILLDLVDPDQEVYVDDEATKSEEHNVLADALAHLIRILLCYAHRQNLRRRTQPPPALSPKRRHIPEYQLLRPIMAYLQHSFHVRWLETFMKDVYGVLQSAGLSCSFTATPYSSVNLSNIDRSVPKVEGLIRQFLLPLESTFSADLLTPQSSFKVKSRTNLSVPPFGTQFEILLNLPHYPDVHPPHRIGLHDQAANIITHFIMLDIVAAIELQTSPALSISKTEAKSVSWEATYPHHGELLSVSIDGKQKKMKVILSRDELTIQTYDVLGLERYSRAAPETTPGLQTHTWKAGPTTAPSLMEYVAAVSQR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 17, Mediator complex subunit 17.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 17 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBEM_ECO57
Sequence: MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL
What is the function of this protein?
Hydrolyzes deaminated glutathione (dGSH) to 2-oxoglutarate and L-cysteinylglycine, and no activity on glutathione or L-glutamine.  May function as a metabolite repair enzyme.
What are the official names of this protein?
Deaminated glutathione amidase, dGSH amidase, Nitrilase homolog 1.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: ALDH2_MESAU
Sequence: SAAATSAVPAPNQQPEVFCNQIFINNEWHDAVSKKTFPTVNPSTGEVICQVAEGSKEDVDKAVKAARAAFQLGSPWRRMDASDRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEVGHLIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDVYDEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKILGYIKSGQQEGAKLLCGGGAAADRGYFIQPTVFGDVKDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSKYGLAAAVFTKDLDKANYLSQALQAGTVWINCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTIKVPQKNS
What is the function of this protein?
Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage.
What are the official names of this protein?
Aldehyde dehydrogenase, mitochondrial, ALDH class 2, ALDH-E2, ALDH1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: YBEY_BRUAB
Sequence: MSDNAIHIDIMIEAGNWPDEASLESLVSKSVAAAWNNLGLKSATSELSVVFTDDASIQLLNGEWRGKDKPTNVLSFPAFPVKAGSQPGPMLGDIVIARETVEREAKEEGKPIENHLSHLVVHGFLHLLGYDHETDEEAEVMEAREREILHALAIPDPYAVSDEDINND
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_HALS3
Sequence: MDAALGPPDAMAASEGDLTPMMSQYFELTRRYDDALVLFQVGDFYELFCAAAETAARICEVTLTAREDSTGQYPMAGVPIDTAEPYIEALLDAGYRVAVADQVQDPDEVSGVVDRAVTRVVTPGTVTEDELLGGADNNFVAALAGGRDADAGFGLALLDVSTGDCYATRLGDEARVRDELGRFTPAELVVGPGVDADRFADEAFVAAYDDDAFEPAAARERVADYFGGEDVLPTTAELRACGALLSYAEYTRGGAGDSQRLTYLNHVTRYSPTEHLQMDAVALRSLELFEQRSVHGTDGTALVDVLDETACALGRRKLTDWLRRPLVDSDAIAARHDAVGELVADPLSREELHEHLRDVYDIERLVSRVSRGRANARDLRALADTLAVVPEVRGLLADADARKLQSLREALDDLPEIRGLLDRAIVADPPQELTDGGVIRDGYDERLDDLRATERAGKQWVDDLEASERERTGVDSLKVGQNSVHGYYIEVTKANMDAVPEDYQRRQTLKNAERYVTPELKEREEEIVRAEQRAQDLEYELFVGIRERVAEAAERMQAVARALAAVDALASFAAVAAAHDYTKPVMGGDGIHIEGGRHPVVERTESGFVPNDTTLNDDRRVAVITGPNMSGKSTYMRQVAVIVVLAQAGCFVPAAAAELRVVDRVFTRVGASDDIAGGRSTFMVEMTELASILRAATDESLVLLDEVGRGTATTDGLAIARAVTEHIHDAVGATTLFATHHHELTADADRLPDALNLHFAATRGDDGVAFEHAVRAGAATASYGVEVARTAGVPEPVVDRARELLDAPATADGGDGGTTPTADANGQRGAAAGIVAELRDVSVAELTPIEALNVLNDLASRVD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS 2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.