PharMolix/UniProtQA huggingface dataset:
Protein: RL18_CHRSD
Sequence: MNAKKEARLRRARRARAKIREQGVSRLSVNRTPRHIYAQIISPDGGQVLASASTLDKSLREGSTGNSDAAAKVGALIAERAKEAGITEVAFDRAGFKYHGRVKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DCDB_MYCGI
Sequence: MLLSDRDIRAEFQAGRLGLDPFDDSLIQPSSVDVRLDNLFRVFNNTRYTHIDPAQRQDDLTSLVEPKEGEPFVLHPGEFVLGATLERCTLPDDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCLLRLTSPAQHPYGSSQVGSKYQGQRGPTPSKSYQNFVKSN
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: BGAL_ENTAG
Sequence: MFTASPMSLSKILARRDWENPGVTQWHRLPAHAPFNSWRDEASARADDNASRKRSLNGDWQFSYYAAPEQVPDSWVTEDCADAVTTPVPSNWQMQGFDTPIYTNDTYPIPVNPPFVPAENPTGCYSLTFEVDEQWLESGQTRIVFDGVNSAFYLWCNGKWMGYSQDSRLPAEFDLSAVLRPGTNRLAVLVLRWCDGSYLEDQDMWRMSGIFRDVSLLHKPHTHIADYHAVTELNADYDRAKLQVEVALAGEQFADCEVAVTLWRDGLSVATVSAKPGSAIIDERGNWAERLNVTLPVKDPALWSAETPELYRLTFALRDGQGEILDVEACDVGFRCVEISNGLLKVNGKPLLIRGVNRHEHHPENGQVMDEATMCRDIELMKQHNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMSRLADDPRWLPAMSERVTRMVLRDRNHPSIIIWSLGNESGHGANHDALYRWVKTTDPTRPVQYEGGGANTAATDIVCPMYARVDQDQPFEAVPKWSLKKWIGMPDETRPLILCEYAHAMGNSFGGFAKYWQAFRNHPRLQGGFVWDWVDQALTKKDDNGNAFWAYGGDFGDTPNDRQFCLNGLVFPDRTPHPALFEAQRAQQFFTFTLVSTSPLVIDVHSDYLFRQCDNEQLRWNIARDGEVLASGEVALTIAPQQTQRIEIDAPEFAAAAGEIWLNVDIVQTAATAWSPADHRCAWDQWQLPAPLYIAPPVEGTAKPDLKVKEDVLEVSHQSQRWHFDRASGNLTQWWNNGTATLLAPLSDNFTRAPLDNDIGVSEATRIDPNAWVERWKAAGMYNLTPRLLLCEGEQLAQAVTITTLHAWESNGKALFLSRKVWKIDRAGVLHGDVQVQVANDIPQPARIGLSCQLAQTPQTASWLGLGPDENYPDRKLAARQGRWTLPLDALHTAYIFPTDNGLRCDTRELTFDTHQMQGDFHFSLSRYSQQQLRDTSHHHLLEAEPGCWLNIDAFHMGVGGDDSWSPSVSPEFILQRREMRYAFSWRQD
What is the function of this protein?
This beta-galactosidase is also able to catalyze glycosyl transfer to a series of acceptors, including hexose, pentose, beta- or alpha-disaccharides, hexahydroxy alcohol, cyclitol, and aromatic glycosides, resulting in the production of galacto-oligosaccharides (GOS).
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Bga, Lactase, Transglycosylating beta-galactosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: LGT_LISMH
Sequence: MGNGVQPLDPVAIQIGSISVKWYGVIIASAVVIALLLALSEANKRKMDKEIIVDLLIWAIPISIISARIYYVIFEWDFYKNNLGEIVKIWHGGIAIYGALIGAVLTAIIFSRIKKISFWQLADVVAPSLIIAQAIGRWGNFMNQEAHGAETTRAFLEGLHLPDFIINQMYIDGAYYQPTFLYESLWNVLGFIILLIIRRTKIRRGELFLGYVIWYSFGRFFIEGMRTDSLMWGDFRVSQVLSLLLIVLSIGIIIYRRVKMNPPYYMEDKFGKVVKKK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYC_BURCJ
Sequence: MESLRIYNTLARDKQVFVPRQSGEVRMYVCGITVYDYCHVGHARMLVVFDLVQRWLRAIGYRVTYVRNITDIDDKIIRRAVENGETIKSLTDRFIGAMHEDESALGIQRPDIEPRATQFIPQMLGMIETLETNGYAYQASDGDVNYSVRKFTNYGKLSGKSLDDLRAGERVAANDAKEDPLDFVLWKRAKPEDPEGASWASKYGMGRPGWHIECSAMGCSLLGNHFDIHGGGQDLQFPHHENEIAQSEGATGETFVNYWMHNGFVQVDNEKMSKSLGNFFTIREVLERYDAEVMRFFIVRTHYRSPLNYSDVHLDDARASLTRLYTALKDVDADTLALDWNEPHAQRFAAAMNDDFNTPVAVATLFELAGEVNRTRDASLARQLKQLAGLLGLLGREPRAFLQQASGAAQAGGLAADEIEAKIAARVAAKQAKDYAEADRIRAELLEAGIALEDKPGGSTEWRRV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED18_ARATH
Sequence: MSMECVVQGIIETQHVEALEILLQGLCGVQRERLRVHELCLRSGPNLGVVSSEVRLLCDLDQPEPTWTVKHVGGAMRGAGADQISVLVRNMIESKVSKNALRMFYALGYKLDHELLKVGFAFHFQRTAHISVSVSSVNKMPKVHAIDEAVPVTPGMQIVDVTAPATSENYSEVAAAVSSFCEFLAPLVHLSKPSISTGVVPTAAAAAASLMSDGGGTTL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors (PubMed:22021418, PubMed:24451981).  Involved in the regulation of histone H3 lysine tri-methylation (H3K36me3).  Associates with the promoter, coding and terminator regions of target genes suggesting its function in transcription initiation, elongation and termination.  Multifunctional protein which regulates plant immunity, especially during necrotrophic fungal infection (e. g.  B. cinerea and A. brassicicola), flowering time and responses to hormones (e. g.  abscisic acid ABA and ethylene) through interactions with distinct transcription factors (PubMed:24451981).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACADV_BOVIN
Sequence: MRAARMAQSTGRQLLRLRGVSSWPGELLGQPRPGPARRPYASGVAQAAVDQSDSQPSEASTREKRANSVSKSFAVGTFKGQLTTDQVFPYPSVLNEDQTQFLKELVGPVTRFFEEVNDAAKNDMLERVEETTMQGLKELGAFGLQVPNELGGVGLCNTQYARLVEIVGMYDLGVGIVLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETIAAFCLTEPSSGSDAASIRSSAVPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPVTDTATGAVKEKITAFVVERSFGGVTHGPPEKKMGIKASNTAEVYFDGVRVPAENVLGEVGGGFKVAMHILNNGRFGMAAALAGTMKGIIAKAVDHAANRTQFGEKIHNFGLIQEKLARMAMLQYVTESMAYMVSANMDQGSTDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGNALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGIVHQELSRSGELAVQALEQFATVVEAKLIKHKKDIINEQFLLQRLADSAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDSWCIEAAARIRENMTALQSDPQQQELFRNFKSISKALVERGGVVTSNPLGF
What is the function of this protein?
Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats.  The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA.  Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains.
What are the official names of this protein?
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial, VLCAD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: ADE_CUPPJ
Sequence: MTIDAALADKIRRTPKAELHVHIEGTLEPELIFRLAQRNHVNLPYPSVEALRAAYAFTDLQSFLDIYYAGASVLLTEEDFFDMTMDYVKRAVADNVRHAEIFFDPQTHTARGVPIGTVIDGISDALAQARTEYDFSSSLILCFLRHLSEEDAFATLEAALPYRDRFVGVGLDSSEKGNPPEKFARVFTRARELGLHLVAHAGEEGPAQYVTDALDILKVERIDHGVRSIDDAALIERLARERVALTVCPLSNQKLKVHPDLSEHPLKRMLDAGVAITLHSDDPAYFGGYMNANWEATFAALPLDAADAHKLARNSFEAAFLPPMQKAEFLAEVDHFWSATPTSPPATAPAA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: PSAC_PROM0
Sequence: MSHAVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGDETSRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CY24A_RABIT
Sequence: MGQIEWAMWANEQALASGLILVAGGIVATAGRFTQWYFGTYAIAAGVLVCLLEYPRGSRAKGSTLERCGQRYLTAVLKLLGPLSRNYYFRAALHLALSVPAGFLLATILGTVCLVIASIIYLLAAVRGEQWTPIEPRPKERPQVGGTIKQPPSNPPPRPPVEARKKPGEEDATPAGGPPGGPRVNPIPVTDEVV
What is the function of this protein?
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.  Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
What are the official names of this protein?
Cytochrome b-245 light chain, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox, p22phox.
What is the protein family that this protein belongs to?
Belongs to the p22phox family.
What are the subcellular locations of this protein?
Cell membrane. Note=As unassembled monomer may localize to the endoplasmic reticulum.
Protein: RL25_BURA4
Sequence: MKVVAFERQEQGTGASRRLRNAGKTTGIVYGGEAAPQKIELDHNALWHALKKEAFHSSILDLEVAGQSQQVLLRDVQYHPFKQLVLHVDFQRVDAKKKLHTKVPLHFLNAEVSPAVKLSSAVVSHVATEIEIECLPSALPEFLEVDLSKIEAGQSLHAKDIALPKGVALVAHIDAENPVVASATIPAGAVSDAAGEGETPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: TTGI_PSEPT
Sequence: MKFKSLPMFALLMLGGCSLIPDYQQPAAPMQAQWPTGQAYGGQGDQRSIATALPKAKEFFKDPALVRLLDAALENNRDLRIAAKNVESYRALYRIQRAERFPTLDGQASGNRTRLPDDLSPTGDSRIDSQYQVGLVTAYELDLFGRIRSLSNQALEKYLATEEAQRSVQIALIGDVATTYFLWRTDQALLELTEATLTSYVESLAMIESSAWAGTSSELDVRQARTLVNQAQAQQALYTRRIAQDVNALELLLGSKIPTDLPKNSPLAMSALGKVPAGLPADLLLNRPDIRSAEHQLMAANANIGAARAAFFPRISLTASAGSASSDLDGLFNSGSDSWSFAPQISVPIFNAGKLRANLDYAELQKDVGVATYEKSIQTAFREVADGLAARGTYGKQLSAQSELVDNYKAYFSLAQQRYDQGVDSYLTVLDAQRELFSSQQKLLNDQLDQINSEVQLYKALGGGWSVSQN
What is the function of this protein?
The outer membrane component of an organic solvent efflux pump.  Involved in export of a number of organic solvents, including toluene and styrene.  This is the most important solvent efflux pump in this strain, although it can export AMP and some antibiotics.
What are the official names of this protein?
Toluene efflux pump outer membrane protein TtgI.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ONCO_HUMAN
Sequence: MSITDVLSADDIAAALQECRDPDTFEPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEMVHS
What is the function of this protein?
Has some calmodulin-like activity with respect to enzyme activation and growth regulation.  Binds two calcium ions.
What are the official names of this protein?
Oncomodulin-1, OM, Parvalbumin beta.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: PHO90_YEAST
Sequence: MRFSHFLKYNAVPEWQNHYMDYSELKNLIYTLQTDELQVGDNEEGFGAGKSSNITDRFKNKFSFKNAKEDTSSGMNKDAGIVEETIELRELPTAQTVAAKPSPFRRMKEKIFYKRRSSSASSVSSTANENLQLDTYDTFVGDLTAEKQKVDDFYKRTEAKFYDKFDALVKDLKKIGVIEYDIDDDTLFNEPIASTNDEVPPLDLDDDEDDDEFYDDQSNIEDNTALLHHSQYNIKSQKKSLLKKSIVNLYIDLCQLKSFIELNRIGFAKITKKSDKVLHLNTRTELIESEQFFKDTYAFQAETIELLNSKISQLVTFYARITDRPHNISHSKQELKSYLHDHIVWERSNTWKDMLGLLSQADELTPKETEYNANKLVGKLDLEYYRWPLPRPINLKFTSINNVALPKLFFTKKAYKIYFIILVTGLLLGIKTFNDAAQHRCMALVECVAFLWASEAIPLHITAFLVPLLVVLFKVLKTSDGAIMSAASASSEILAAMWSSTIMILLAGFTLGEVLAQYNIAKVLASWLLAFAGCKPRNVLLMAMCVVFFLSMWISNVAAPVLTYSLLSPLLDAMDADSPFAQALVLGVALAANIGGMSSPISSPQNIISMSYLKPYGIGWGQFFAVALPSGILAMLLVWILLFTTFKMNKTKLEKFKPIKTKFTVKQYYIITVTVATILLWCVESQIEGAFGSSGQIAIIPIVLFFGTGLLSTQDLNAFPWSIVILAMGGIALGKAVSSSGLLSTIAKALQKKIENDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQEVGDKLGNPKAAPILVFGCALLSSCGMGLASSGFPNVTAISKVDRKGDRYLSVMTFLTRGVPASILAFLCVITLGYGIMASVVKGNATSA
What is the function of this protein?
Low-affinity phosphate transporter involved in the control of cellular phosphate levels.
What are the official names of this protein?
Low-affinity phosphate transporter PHO90.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PELO_DROME
Sequence: MKLLGKYVDKGMQGNVTLVPEESEDMWHAYNLIAKGDSVRSTTIRKVQNETATGSSTSSRVRTTLTIAVESIDFDTQACVLRLKGRNIEENQYVKMGAYHTLDLELNRKFELRKPEWDTIALERIEMACDPTQSADVAAVVMQEGLAHVCLITASMTLVRSKIEVSIPRKRKGSVQQHEKGLAKFYEQVMQSILRHVNFDVVKCVLIASPGFVRDQFYDYMFQQAVKMDYKLLLDNKSKFMLVHASSGFKHSLREILQDPAVLAKMSDTKAAGEVKALEQFYMMLQCEPAKAFYGKKHVLQAAESQAIETLLISDNLFRCQDVSLRKEYVNLVESIRDAGGEVKIFSSMHISGEQLAQLTGIAALLRFPMPELEDSDDDDDEDGAAGGVADSDSD
What is the function of this protein?
Cotranslational quality control factor involved in the No-Go Decay (NGD) pathway (PubMed:29861391).  In the presence of pix and HSB1, is required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes (By similarity).  Together with HBS1 and in presence of pix, recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs; this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway (By similarity).  Required prior to the first meiotic division for spindle formation and nuclear envelope breakdown during spermatogenesis (PubMed:7588080).  Together with HBS1, promotes spermatid individualization during spermatogenesis (PubMed:30824860).  Required for ovarian germ line stem cell self-renewal and oocyte development during oogenesis (PubMed:16280348).  Together with HSB1, required for transposon silencing in the ovary and testis (PubMed:26124316).  As part of the Pink1-regulated signaling, is recruited to damaged mitochondrial and is required for recruitment of autophagy receptors and induction of mitophagy (PubMed:29861391).  Required for normal eye patterning and for mitotic divisions in the ovary (PubMed:7588080).
What are the official names of this protein?
Protein pelota.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: FDHE_SHIB3
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLDDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALF2_PEA
Sequence: MSHFKSKYHDELIANAAYIGTPGKGILAADESTGTIGKRLSSINVENVESNRQALRELLFTASWLFLQYLSGVILFEETLYQKTAAGKPFVDVLNEAGVLPGIKVDKGTVELAGTDGETTTQGLDGLGARCRKYYEAGARFAKWRAVLKIGANEPSEHSIHENAYGLARYAVICQENGLVPIVEPEILVDGSHDILKCAAITERVLAATYKALSDHHVILEGTLLKPNMVTPGSDAPKVAPEVIAEHTVRALQRTVPAAVPAVVFLSGGQSEEEASVNLNAINQIKGKKPWTLSFSFGRALQQSTLKAWGGKTENVKAAQDALLTRAKANSEATLGTYKGASNLGAGASESLHVKDYKY
What are the official names of this protein?
Fructose-bisphosphate aldolase, cytoplasmic isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFA25_MOUSE
Sequence: MKTLVLLSALALLAFQVQADPIQNRDEESKIDEQPGKEDQAVSVSFGDPEGSSLQEECEDLICYCRTRGCKRRERLNGTCRKGHLMYMLWCC
What is the function of this protein?
May have microbicidal activities.
What are the official names of this protein?
Alpha-defensin 25, Defensin-related cryptdin-25.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPA_CAUSK
Sequence: MTKDRIDRRFAALKAENRAGFVTYIMAGDPDAATTLSVLKGLPAAGADLIELGFPFSDPMAEGPTIQRAAQRGLKSGMTLQGTLDLVAGFREGDADTPIILMGYLNPVLNRGFESFAAAAAKAGVDGLIIVDCPPEEAGPLTDALEAEGIALIRLAAPTTDDKRLPMVVRRTSGFVYYVSVAGVTGVKSADAADVAPAVARLRKASGLPVAVGFGIRTPAQAAAVARVADAAVVGSALVDEIEAAAQLNENVTEKVLLKASELAKAVRSARLELA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: IDH3B_RAT
Sequence: MAALSNVRWLTRAVLGARNSGAWRGLRTAASAQAASQSQAQDVRVEGAFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFKEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIYTPMEYKGELASYDMQLRRKLDLFANVVHVKSLPGYKTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRTKSQRIAKFAFDYATKKGRSKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLHPHGG
What is the function of this protein?
Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate.  The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, Isocitric dehydrogenase subunit beta, NAD(+)-specific ICDH subunit beta.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: T12BB_XENLA
Sequence: MSLQKCQEEWGELEKEFQQLQETHKVYKQKLEELSSLQNLCSSYINKHKRRLTELKGNLHGYKHTSNLEEKELIQQIDGTIKERHNAFFDMEAYLPKKNSLYLNLVLGNVNVTLLSKQTKFAYKDEYEKFKLYLTIILLLGAITCRFVLHYRVTDEVFNFLLVWYFCTLTIRESILISNGSRIKGWWVSHHYVSTFLSGVMLTWPDGLMYQMFRNQFLAFSIFQSCVQFLQYYYQSGCLYRLRALGERNHLHLTVEGFQSWMWRGLTFLLPVLFFGHFWQLYNAMTLFGLSRHEECKEWQVFVLALTFLLLFLGNFLTTLKVVHTKFQKNKLKKP
What is the function of this protein?
Necessary for efficient adipogenesis.  Does not show ion channel activity.
What are the official names of this protein?
Transmembrane protein 120B-B.
What is the protein family that this protein belongs to?
Belongs to the TMEM120 family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: ARGJ_STRCO
Sequence: MSVTAAKGFTAAGITAGIKESGSPDLALVVNTGPRRSAAGVFTSNRVKAAPVLWSEQVLKSGEVTAVVLNSGGANACTGPKGFQDTHATAEKAADVLGTGAGEVAVCSTGLIGVLLPMDKLLPGVEAAAGQLSEHGGEKAAIAIKTTDTVHKTSVVTRDGWTVGGMAKGAGMLAPGLATMLVVITTDADLETEALDRALRAATRVTFDRVDSDGCMSTNDTVLLLSSGSSGVTPEYDAFAEAVRTVCDDLGQQLIRDAEGASKDIKVEVVNAATEDEAVQVGRTIARNNLLKCAIHGEDPNWGRVLSAIGTTDAAFEPDRLNVAINGVWVCKNGGVGEDRELVDMRYREVHIVADLAAGDATATIWTNDLTADYVHENSAYSS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEM3_YEAST
Sequence: MVNFDLGQVGEVFRRKDKGAIVSGDNPEEEEDVDASEFEEDEVKPVRTKNRRPKEDAFTQQRLAAINPVLTPRTVLPLYLLIAVVFVIVGGCILAQNSKVDEVTIYYQDCMTNATSSWSDIPSEHWQFVFHKYKTYNTAPQWRFVDDESDDFTKQRGTCQIRFTTPSDMKNNVYLNYVLEKFAANHRRYVLSFSEDQIRGEDASYETVHDATGINCKPLSKNADGKIYYPCGLIANSMFNDTFPLQLTNVGDTSNNYSLTNKGINWESDKKRYKKTKYNYTQIAPPPYWEKMYPDGYNETNIPDIQDWEEFQNWMRPGAFDKITKLIRINKNDTLPAGEYQLDIGLHWPVLEFNGKKGIYLTHGSHLGGRNPFLGIVYLIGGCICAAMALILLTFWLFGGRKIADASSLSWNMK
What is the function of this protein?
Involved in the asymmetrical organization of phosphatidylethanolamine in the plasma membrane.
What are the official names of this protein?
Alkylphosphocholine resistance protein LEM3, Brefeldin-A sensitivity protein 3, Ro-sensitive 3.
What is the protein family that this protein belongs to?
Belongs to the CDC50/LEM3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TM147_DANRE
Sequence: MTLFHFGNCFSLAYFPYFITYKCSGLSEYNAFWRCVQAGATYLFVRLCKMLFLATFFPTWEGGAGVYDFVGEFMKATVDMADLLGLHLVMSRNAGKGEYKIMVAAMGWATAELIMSRCIPLWVGARGIEFDWKYIQMSFDSNISLVHYIAMAAVVWMFTRYDLPKSFRLPVAILLGLCVYKGFLMELFVHVFLLGSWTALLVKAVLTGAISLCSLFLFVTLVHSN
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions.
What are the official names of this protein?
BOS complex subunit TMEM147, Transmembrane protein 147.
What is the protein family that this protein belongs to?
Belongs to the TMEM147 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: OPGG_ECOBW
Sequence: MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYETPKSNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATAVKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAYKFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPSAWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDEDKLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTSIGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.