PharMolix/UniProtQA huggingface dataset:
Protein: PPK5_PERSR
Sequence: SGETSGEGNGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, FXPRL-amide, PerSu-Capa-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAK_STRA5
Sequence: MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVEEFKKENGIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFDDLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQHIVIQSNSGLTDEEIDKMMKDAEANAEADAKRKEEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAQSALDELKKAQESGNLDDMKAKLEALNEKAQALAVKLYEQAAAAQQAAQGAEGAQSADSSSKGDDVVDGEFTEK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SHKB1_RAT
Sequence: MAVPTTAVEGVRSRGAPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQVREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGPQQIGGRPAPVRRSNTMPPNLGNAGLLGRMLDDRAPPSPSGQPEEPGMVRLVCGHHNWIAVAYTHFLVCYRLKEASGWQLAFSSPRLDWPIERLALTARVLGGAPGEHDKMVAAATGSEILLWALQAQGGGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCSNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAEDGVTALSVYLTPKTSDSGNWIEIAYGTSSGVVRVIVQHPETVGSGPQLFQTFSVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKILALESADGLGGCSAGNDIGPYGERDDQQVFIQKVVPNASQLFVRLSSTGQRVCSVRSVDGSATTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLGQTPAGGLTEEELMDQLEQCELSPLTSSRASFPSPSPRTSLTSLHSASSNTSLCGHRGSPSPPQAGARSRGAGSFVDRFKELARGAPELRGPPTPAPRPSTSLGNPLILPKNTLNETSF
What is the function of this protein?
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1.  Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
What are the official names of this protein?
SH3KBP1-binding protein 1, SETA-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the KCTD3 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RNH2_LIMF3
Sequence: MSKQSVAQVRALLSSITDPQDPRLAEFKDDPRKGVQAALNQFAKRLEKRAEARAAFLNRFRYENQLWQAGHQYVAGIDEVGRGPLAGPVVTCAVVLDSQFDLVGVTDSKQLSRHEREQLYLRILDEAVEVSLAVSPAQEIDRLNIYAATQTAMIRSVKALHHQPSHLIVDAVPLDIPVPQTTLIKGDQKSISVAAASIVAKEYRDHLMAIYDRLYPGYGFKDNMGYGTAAHLAGLEQLGACPIHRRTFRPVPDYVN
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_LEGPL
Sequence: MKHFIEISQLSSEQIESLLQRALYFKHTKQYPSYSQSIIANLFYENSTRTRISFELAERHLAMSVVNLDLETSSETKGEAIEDTIRTLAAMGIQYFVIRHKQDGLQQNLANKLGDTVHIINAGDGTHAHPSQAILDMVTIVEQKKQLDKLKIAILGNIKHSRVANSFQCICSKLGVGELVLISPEIWQPSQVHFGRVTDNLNEGLEGADVVICLRVQKERLLQDDHLDLDFYRNNFALTQKSLSYAKPDAMVMHPGPMNRGVEIDSEVADGNQSCILQQVTNGVYARMAILESLIAS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: NR2C2_HUMAN
Sequence: MTSPSPRIQIISTDSAVASPQRIQIVTDQQTGQKIQIVTAVDASGSPKQQFILTSPDGAGTGKVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGKTDVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFKRSVRKNLTYSCRSNQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCAASTEKIYIRKDLRSPLIATPTFVADKDGARQTGLLDPGMLVNIQQPLIREDGTVLLATDSKAETSQGALGTLANVVTSLANLSESLNNGDTSEIQPEDQSASEITRAFDTLAKALNTTDSSSSPSLADGIDTSGGGSIHVISRDQSTPIIEVEGPLLSDTHVTFKLTMPSPMPEYLNVHYICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQEDKLSGDRIKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTSTSQIEKFQEKAQMELQDYVQKTYSEDTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSIIPYILKMETAEYNGQITGASL
What is the function of this protein?
Orphan nuclear receptor that can act as a repressor or activator of transcription.  An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways.  May regulate gene expression during the late phase of spermatogenesis.  Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1.  Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences.  Plays a fundamental role in early embryonic development and embryonic stem cells.  Required for normal spermatogenesis and cerebellum development.  Appears to be important for neurodevelopmentally regulated behavior (By similarity).  Activates transcriptional activity of LHCG.  Antagonist of PPARA-mediated transactivation.
What are the official names of this protein?
Nuclear receptor subfamily 2 group C member 2, Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, Testicular receptor 4.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSF2_ASHGO
Sequence: MALPRNLQDTFSLQEVQFLVENEPIKIMPRITTKPIRRKAASTPSAGSSVRWKLITTDDHNVNNMVAMSSTEVSLWLALLLKQQGKCSIVAPAWLTIKQLDSFIEFELQNTSRFANLPWNWLIIAHLLFQKAADDFRDPVHILRAKIQDLREARLGKIAKGLQHLNESHLQLDNLSLSEINEMRPFAVGVMDKLRDIHAAAADREQYANNI
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.  Has a role in chromosome segregation (By similarity).
What are the official names of this protein?
DNA replication complex GINS protein PSF2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14_CRIGR
Sequence: MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: LEUC_PSYA2
Sequence: MAGQTLYDKLWNAHEVTKRDDGSSLIYIDRHLLHEVTSPQAFEGLELANRAPWRLSANIASPDHNVPTVTKERSEGVAGIKDKVSRLQVLTLDNNCAKFDIAEFTINDARQGILHVVGPEQGLVLPGMTVVCGDSHTATHGALGCLAHGIGTSEVEHVLATQCLIQKKSKNMQIRVTGELGVGVTSKDVVLAIIAKIGTAGGTGHAIEFAGQVFEDMSMEGRMTVCNMAIEAGARVGMVAVDDTTINYVKGRPYAPNESQWQQAEAYWRTFYSDDDAVFDSVVEIDGSQIAPQVSWGTSPEMVVDVTQSVPTLDQAIDEAQEEGWLRAYTYMGLEAGQKITDIQLDRIFIGSCTNSRIEDLRDAAAVIKGRKVADNIKEAIVVAGSGQVKLQAEAEGLDALFTDAGFEWREPGCSMCLAMNADKLEPQEHCASTSNRNFEGRQGNGGRTHLVSPAMAAAAALAGHFVDVRTF
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: IMB2_YEAST
Sequence: MASTWKPAEDYVLQLATLLQNCMSPNPEIRNNAMEAMENFQLQPEFLNYLCYILIEGESDDVLKQHYSLQDLQNNRATAGMLLKNSMLGGNNLIKSNSHDLGYVKSNIIHGLYNSNNNLVSNVTGIVITTLFSTYYRQHRDDPTGLQMLYQLLELTSNGNEPSIKALSKIMEDSAQFFQLEWSGNTKPMEALLDSFFRFISNPNFSPVIRSESVKCINTVIPLQTQSFIVRLDKFLEIIFQLAQNDENDLVRAQICISFSFLLEFRPDKLVSHLDGIVQFMLHLITTVNEEKVAIEACEFLHAFATSPNIPEHILQPYVKDIVPILLSKMVYNEESIVLLEASNDDDAFLEDKDEDIKPIAPRIVKKKEAGNGEDADDNEDDDDDDDDEDGDVDTQWNLRKCSAATLDVMTNILPHQVMDIAFPFLREHLGSDRWFIREATILALGAMAEGGMKYFNDGLPALIPFLVEQLNDKWAPVRKMTCWTLSRFSPWILQDHTEFLIPVLEPIINTLMDKKKDVQEAAISSVAVFIENADSELVETLFYSQLLTSFDKCLKYYKKKNLIILYDAIGRFAEKCALDETAMQIILPPLIEKWALLSDSDKELWPLLECLSCVASSLGERFMPMAPEVYNRAFRILCHCVELEAKSHQDPTIVVPEKDFIITSLDLIDGLVQGLGAHSQDLLFPQGTKDLTILKIMLECLQDPVHEVRQSCFALLGDIVYFFNSELVIGNLEDFLKLIGTEIMHNDDSDGTPAVINAIWALGLISERIDLNTYIIDMSRIILDLFTTNTQIVDSSVMENLSVTIGKMGLTHPEVFSSGAFANDSNWNKWCLSVNALDDVEEKSSAYMGFLKIINLTSTEVTMSNDTIHKIVTGLSSNVEANVFAQEIYTFLMNHSAQISAINFTPDEISFLQQFTS
What is the function of this protein?
Functions in nuclear protein import as nuclear transport receptor.  Serves as receptor for arginine/glycine-rich nuclear localization signals (rg-NLS) and PY-NLS in cargo substrates.  Its predominant cargo substrate seems to be mRNA-binding proteins.  Required for nuclear transport of NAB2, HRP1/NAB4 and TFG2.  Mediates docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to repeat-containing nucleoporins (PubMed:8849456, PubMed:9488461, PubMed:10506153, PubMed:19366694).  The complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism (PubMed:11423015).  At the nucleoplasmic side of the NPC, GTP-Ran binding leads to release of the cargo.  Efficient GTP-Ran-mediated substrate release requires RNA (PubMed:10506153).  The importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (PubMed:11423015).
What are the official names of this protein?
Importin subunit beta-2, Importin-104, Karyopherin subunit beta-2, Karyopherin-104, Transportin, TRN.
What is the protein family that this protein belongs to?
Belongs to the importin beta family. Importin beta-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus. Note=Predominantly cytoplasmic.
Protein: ZAPD_PHOPR
Sequence: MQTNRFEHPLNEKVRIYLRLEYLIRQMTHASQLSDQWQHQIFFRALFDLLEILDQVQLKTELAKDLEKQRCKLKNWLNIDGVDQNALLELLDSMDMAHHKLIAANRLGQDLRDDRFLSGIKQRFSIPGGSCCFDLPTLHHWLHLPLAHKQNDLSTWLSQLTEMTDALNLWLRFTRESGPFQPQIARAGFFQHTAEDASLLRLQICPSYGVYPMISGHRGRFAIRFIPFEEGATIADTIEFKLAIC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: RLMM_ECO8A
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_LISIN
Sequence: MAKKGKKYQDALKQIDANKVYTAEEAVELAKKIDFAKFDATVEVAFRLGVDPKKADQQIRGAVVLPNGTGKTQRVLVFAKGEKAKEAEAAGADYVGESEFVEKINQGWFEFDVIVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVTKAVNEIKAGKVEYRVDKAGNVHAAIGKVSFDAAKLVENFRTVNDVLQKAKPAAAKGTYVKNLSVTTTFGPGIKVDPASL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RUVA_CHLPB
Sequence: MFTYFRGELIEASPDEAVIEVSGVGYLLSISATTYRQLPEPGREVLVLAHLHVKEDLMQLFGFLEEEERQLFRLLLSISGVGPKLALAILSGLQVHEIQEAIVSNMPERLFEITGVGKKTAARIVLELRDRILKLRPSGGTKSVSRLSESSMRDDAVNALVTLGFLRSVAQKAVTESLTSLRNPQVEDLVRDALLTIRTP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RBFA_LACLC
Sequence: MGNSFRSDRVAVEIQREINDILRNKVRDPRVQDVNITDVQLTGDLSQATVYYSLLSNLASDNEKAATALKKATGLFKSELAKRMTIFKIPDLTFAKDESVEYGSKIDEILTWA
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBOH_BURP1
Sequence: MTAIRGGSRRAPGLALALLGGVLLGACHGDENAQVNALPGFVSGSVRKTAYDGASDDLLTAGLGKTGLGSDTRPGFANPAQPSAAELRRLAIYSNYRALVDITPNGGYGRFWGPNVDLAGNDTLGEGKIAGTEYLAYSDDGSGRKNVTLLVQVPASFDPANPCIVTATASGSRGVYGAIAAAGEWGLKRGCAVAYNDKGGGNGAHEIGTGVVTLIDGTLATASSAGSSSLFTASESSSTLAAFNSAFPNRYAYKHAHSQQNPEQDWGRVTLQAVEFAYWALNEQFGPVVDGTRHGIRYRPGDITTIAASVSNGGGSALAAAEQDTRGWITAVVVGEPQINVRMTPGVTVEQGGAPVPSFGRPLADYATLANLLQPCAAAAVAATGAPYLSALPMGVTQSIRTQRCATLAAAGLVSGADTASQASDALAQLHAAGYLADSDLLQAPMWDSQAMPAIAVTYANAYTRSRVTDNLCNFSFATTNPVTGAVAAPAVSPMTNLFGAGNGVPPTNGINLVFNGASGGVDHRLATPDASFAGAFCLRQLWTANQLGIGTNVDAVRVAANLQHKPAIIVHGRSDALVPVNHASRAYVAQNSATEGRASQLSFYEVTNGQHFDAFLSVPGFDTRFVPVHYYDEQALNLMWNHLKSGAPLPPSQVIRTVPRGGVPGAAPALSTANLPPIVQSPGANAIAVNAGVIDVPL
What is the function of this protein?
Participates in the degradation of poly-3-hydroxybutyrate (PHB).  It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
What are the official names of this protein?
D-(-)-3-hydroxybutyrate oligomer hydrolase, 3HB-oligomer hydrolase, 3HBOH.
What is the protein family that this protein belongs to?
Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NKX11_HUMAN
Sequence: MSASGPEAPGDIPALPPPPQPGSGPAPPAPAAAAQEAMDGRAELPAFPRAGAPPLAASDTVPAAPEGAGAARPAAPLRPTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAPAPAASGRPPRAEELERRALAGAGGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDDEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSPVAQGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHGPGGLVCAAQLPFLSSPAVLSPFVLGSQTYGAPAFYAPHL
What is the function of this protein?
May be required for the coordinated crosstalk of factors involved in the maintenance of energy homeostasis, possibly by regulating the transcription of specific factors involved in energy balance.
What are the official names of this protein?
NK1 transcription factor-related protein 1, Homeobox protein 153, HPX-153, Homeobox protein SAX-2, NKX-1.1.
What is the protein family that this protein belongs to?
Belongs to the NK-1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AZOR_RUMCH
Sequence: MKKLLYISVNTKPEEMSSSKTVARKLINSILEKHPSMALEEVDLYREHIPQLKYSYFESRSAIVNSEALAKLPQDEQNEVTQIIKLCDQFRAADIYIIASPMWSLSFPAPLKEYIDCVVQSGKTIAFDENKPYGLLNDKERTFIYVQSSGANIPWIIRPALNKGLNYVHDIIRFLGISKFEELLVDGTGTTELERQEAIEKAASRIETLVDQI
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: VKT7_PSETT
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPKFCELLPDTGSCEDFTGAFHYSTRDRECIEFIYGGCGGNANNFKTLEECESTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor textilinin-7, Txln-7.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSH_SYNY3
Sequence: MELEHPDDLYYLDSHEYVRFDGETATIGLSAFAVDELGDIVFVELPEEGDKVEFEQSMGAVESVKAASDLYSPVTGTVIEKNSALEDQPELLNQDPYGEEGWLIKVRLDDVEDAKEGLMAAGDYRATLETGD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RSMC_ACTSZ
Sequence: MISLESQVLERHLSIFADKTLLFAGGVNDDFPVQIQKIAKTVTVWSWYFDYANAQGRKSAVDFSPVCDTQVDVIVYYWTKNKAEVQFQLMQLLANGRDNQEILIVGENRCGVRSAEKMLSAFGDIGKIDSARRCGLYHFRLKKRPHFDINAYWKTYRNPKLDALTVYSLPGVFSADELDGGTELLLSTINTHIRGDVLDLGCGAGVLGAYVKQQNPQARVMLTDIHAMALASAERTLAENRLAGKVLASDVFSHIQGKFDLIISNPPFHDGIGTAYRAVSELIKEARWRLKEDGELRIVANAFLPYPDLLDEHFGSHQVLAKTNKFKVYSVCA
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDF2A_DROPE
Sequence: MLRQLKLTLNISRWIFMPWQRQASASSSQVPPFLAPISDDVIVDYEDPDYLPLPEYPVRPNEPLETRKQRLLYQSRKRGMLENDLLLSTFAAKYLKDFSAEQTAIYDQLINGVSNDWDIYYWATEVKPTPEEYNTEIMKLLKEHVKNAERVTRFRQPDLT
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2-A, mitochondrial, SDH assembly factor 2-A, SDHAF2-A.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CCN4_HUMAN
Sequence: MRWFLPWTLAAVTAAAASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCECCKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYNNGQSFQPNCKYNCTCIDGAVGCTPLCLRVRPPRLWCPHPRRVSIPGHCCEQWVCEDDAKRPRKTAPRDTGAFDAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQESRLCNLRPCDVDIHTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCCIPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN
What is the function of this protein?
Downstream regulator in the Wnt/Frizzled-signaling pathway.  Associated with cell survival.  Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase.  Up-regulates the anti-apoptotic Bcl-X(L) protein.  Adheres to skin and melanoma fibroblasts.  In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
What are the official names of this protein?
CCN family member 4, WNT1-inducible-signaling pathway protein 1, WISP-1, Wnt-1-induced secreted protein.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYDND_CARHZ
Sequence: MLKRSHYCGELRKEHAGQKVILNGWVQRRRDHGGLIFVDLRDRSGIVQVVFSPDVDLEAFRVAEAVRNEYVLAIEGTVRLRPEGTENPNLLTGEVEVYASKVEVLNKAKTPPFYIEDGIDVDEQVRLRYRYLDLRRPEMQRALELRHKAAKAVRDFLDRHGFWEIETPMLTKSTPEGARDFLVPSRLNPGKFYALPQSPQIFKQILMVAGMERYFQIVRCFRDEDLRADRQPEFTQIDIEMSFIDREDIMSLMEEMIAYVFKEAIGVEVKTPFKRISYQEAMLKYGTDKPDLRFGLEITDVTELVKDVEFKVFQTVAHAGGVIRGLNAKGCAGFSRKDLDDLTKFVGNFGAKGLAYLILTPEEVKSPIAKFFKEEELRALINALQGEPGDILFFVADKPEVAAQALGNLRLHLAERLGLIPENEFNFLWVIDFPLLEYDNEEKRFVAMHHPFTAPMDEDLPLMDENPLLVRAKAYDMVLNGVEIGGGSIRIHRRDIQEKMFKLIGLSEEEAKEKFGFMLEAFEYGTPPHGGIAFGFDRLVMLMAGRESIRDVIAFPKTQSATDLMVGAPNVVERRQLKELHIKVDLPVKEQQ
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_METTP
Sequence: MANVVEALVSGGKATAGPPLGPALGPLGVNVAAVVAKINELTKDLNGMQVPVKIIVKSRTEFEIEVGTPPTSALLLKEAGVEKGSGDKKNFVGDISMDQVIKVAEIKRKNLLSSNLKSAVSEIVGTCGTLGIKIDGLTSKEVQKALASGSYDHLFEAKS
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.