PharMolix/UniProtQA huggingface dataset:
Protein: EXSD_PSEAE
Sequence: MEQEDDKQYSREAVFAGRRVSVVGSDARSRGRVPGYASSSLYRESGIISARQLALLQRMLPRLRLEQLFRCEWLQQRLARGLALGREEVRQILLCAAQDDDGWCSELGDRVNLAVPQSMIDWVLLPVYGWWESLLDQAIPGWRLSLVELETQSRQLRVKSEFWSRVAELEPEQAREELARVAKCQARTQEQVAELAGKLETASALAKSAWPNWQRGMATLLASGGLAGFEPIPEVLECLWQPLCRLDDDVGAADAVQAWLHERNLCQAQDHFYWQS
What is the function of this protein?
Negative regulator of the type III secretion system regulon.  Acts by disrupting transcriptional activator ExsA self-association and DNA-binding activity in absence of inducing signals (PubMed:12421316, PubMed:19369699, PubMed:20008065, PubMed:23279839).  Upon host cell contact, this interaction is disrupted by the anti-antiactivator protein ExsC leading to ExsA activation (PubMed:15225323, PubMed:16980486).
What are the official names of this protein?
Transcriptional antiactivator ExsD.
Protein: NS1_I49A1
Sequence: MDSNTITSFQVDCYLWHIRKLLSMRDMCDAPFDDRLRRDQKALKGRGSTLGLDLRVATMEGKKIVEDILESETDENLKIAIASSPAPRYIMDMSIEEISREWYMLMPRQKVTGGLMVKMDQAIMGKRIILKANFSVLFDQLETLVSLRAFTEDGAIVAVISPIPSMPGHSTEDVKNAIGILIGGLEWNDNSIRASENIQRFAWGIRDEDGGPPLPPKQKRYMARRIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: ARMT1_MOUSE
Sequence: MAESPAFLSAKDEGSFAYLTIKDRTPQILTKVIDTLHRHKSEFFEKHGEEGIEAEKKAISLLSKLRNELQTDKPITPLVDKCVDTHIWNQYLEYQRSLLNEGDGEPRWFFSPWLFVECYMYRRIHEAIMQSPPIHDFDVFKESKEENFFESQGSIDALCSHLLQLKPVKGLREEQIQDEFFKLLQISLWGNKCDLSLSGGESSSQKANIINCLQDLKPFILINDTESLWALLSKLKKTVETPVVRVDIVLDNSGFELITDLVLADFLFSSELATEIHFHGKSIPWFVSDVTEHDFNWIVEHMKSSNLESMSTCGACWEAYARMGRWAYHDHAFWTLPHPYCVMPQVAPDLYAELQKAHLILFKGDLNYRKLMGDRKWKFTFPFHQALSGFHPAPLCSIRTLKCELQVGLQPGQAEQLTASDPHWLTTGRYGILQFDGPL
What is the function of this protein?
Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similarity).  Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism (By similarity).  Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues (By similarity).  Possibly methylates PCNA, suggesting it is involved in the DNA damage response (By similarity).
What are the official names of this protein?
Damage-control phosphatase ARMT1, Acidic residue methyltransferase 1, Protein-glutamate O-methyltransferase, Sugar phosphate phosphatase ARMT1.
What is the protein family that this protein belongs to?
Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
Protein: DAPE_BURA4
Sequence: MSATLALTEQLIARASVTPDDQHCQQIMTERLAALGFECETIASHGVTNLWAVKRGADGRDGKLLAFAGHTDVVPTGPLEQWTSPPFVPAHRDGKLYGRGAADMKTSLAAFVVASEEFVAAHPGHRGAIAFLITSDEEGPATDGTVKVVELLEARGERVDYCIVGEPTSTAELGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDAGNEYFPPTTWQVSNLHAGTGATNVIPGHADLMFNFRFSTASTVEGLQARVHAILDKHGLEYTLKWSVSGLPFLTPRGDLSNALENAIRAETGLTTELSTTGGTSDGRFIARICPQVIEFGPPNGSIHKIDEHIDVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PLM9_PLAF7
Sequence: MFFINFKKIKKKQFPIYLTQHRIITVFLIFIYFINLKDCFHINNSRILSDVDKHRGLYYNIPKCNVCHKCSICTHENGEAQNVIPMVAIPSKRKHIQDINKEREENKYPLHIFEEKDIYNNKDNVVKKEDIYKLRKKKKQKKNCLNFLEKDTMFLSPSHDKETFHINHMNKIKDEKYKQEYEEEKEIYDNTNTSQEKNETNNEQNLNINLINNDKVTLPLQQLEDSQYVGYIQIGTPPQTIRPIFDTGSTNIWIVSTKCKDETCLKVHRYNHKLSSSFKYYEPHTNLDIMFGTGIIQGVIGVETFKIGPFEIKNQSFGLVKREKASDNKSNVFERINFEGIVGLAFPEMLSTGKSTLYENLMSSYKLQHNEFSIYIGKDSKYSALIFGGVDKNFFEGDIYMFPVVKEYYWEIHFDGLYIDHQKFCCGVNSIVYDLKKKDQENNKLFFTRKYFRKNKFKTHLRKYLLKKIKHQKKQKHSNHKKKKLNKKKNYLIFDSGTSFNSVPKDEIEYFFRVVPSKKCDDSNIDQVVSSYPNLTYVINKMPFTLTPSQYLVRKNDMCKPAFMEIEVSSEYGHAYILGNATFMRYYYTVYRRGNNNNSSYVGIAKAVHTEENEKYLSSLHNKINNL
What is the function of this protein?
During the asexual blood stage, initiates the proteolytic maturation of several rhoptry proteins and thus, is required for merozoite invasion of host erythrocytes and probably the subsequent development of the ring-stage (PubMed:29074775, PubMed:32109369).  Cleaves rhoptry associated protein 1 RAP1 and apical sushi protein ASP during schizont maturation (PubMed:29074775, PubMed:32109369).  Also cleaves rhoptry protein RON3 (PubMed:32109369).
What are the official names of this protein?
Plasmepsin IX, PfPMIX, Plasmepsin 9.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, rhoptry. Note=In schizonts, localizes to the bulb of rhoptries.
Protein: NIFB_RHIME
Sequence: MSTPMILRESRTSTTFSDQLLENAKSVGCSPPSTAPGDIDPGTWDKIKNHPCFSEEAHHYFARMHVAVAPACNIQCNYCNRKYDCANESRPGVASEKLTPDQAVRKVIAVANEVPQLSVLGIAGPGDACYDWKKTRATFERVAREIPDIRLCISTNGLSLPDHVDELAEMNVDHVTITINMVDPRVGVKIYPWIYYGQRRHTGIDAARILHERQMLGLEMLAERGILTKVNSVMIPGVNDEHLIEVNKVVKGRGALLHNVMPLISNRIHGTYYGLTGQRGPEAFELQALQDRLEGTKLMRHCRHCRADAIGLLGDDRGHEFTLAEIPDEITYDASKRQAYRQLVARERGDHLVAKNEANRTVMSVEYGGSLLIAVATKGGGRINEHFGHAKEFHVYTVSQRGIKLAGRRRVEQYCLGGWGEVATLDHIVVALEGIDILLCVKIGDYPRKQLTQAGLRATEAYGHDYIESALGALYAAEFGIEPPVKTATA
What is the function of this protein?
Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms.  NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.
What are the official names of this protein?
FeMo cofactor biosynthesis protein NifB, Nitrogenase cofactor maturase NifB, Radical SAM assemblase NifB.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. NifB family.
Protein: RS14_LUPLU
Sequence: MSRRKVRDTKEETVTLGPAVSDGEHVFGVARIFASFNDTFIHVTDLSGRETLVRITGGMKVKADRDESSPYAAMLAAQDVATRCKELGITALHIKLRATGGNKTKTPGRGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKSGRRGRRL
What are the official names of this protein?
40S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: G_BPPHK
Sequence: MYQIFVTKHDTAIQTSRFSVTGSITPVAPTGNIPVINTGNITAEHAVVSLYANLTAGTSSDGSFIVAMKVDTSPADPNCVISAGVNLSFAGTSYPIVGIVRFESASDQPTSIAGSQIEHYPIEMSVGSGGVCSARDCVTVDIHPRAFGNNVFVGVICSSAKWTSGRVLGTIATTQVIREYQVLQPLK
What is the function of this protein?
Attaches the circulating virion to the bacterial lipopolysaccharides which serve as receptor for the virus.  Determines the phage host-range.  Probably triggers with protein H the injection of the phage DNA into the host cytoplasm upon conformational changes induced by the interaction with host lipopolysaccharides (By similarity).
What are the official names of this protein?
Major spike protein G, G protein, GPG.
What is the protein family that this protein belongs to?
Belongs to the microvirus G protein family.
What are the subcellular locations of this protein?
Virion.
Protein: CAIB_ECO81
Sequence: MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQIAECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_CALBD
Sequence: MGKLFGTDGVRGVANKELTCELAFDLGRAGAYVLTEMHKKPKILIGKDTRISCDMLEAALCAGLTSVGADVYLAGVVTTPAIAYLVKSHGFDAGIMISASHNPYEFNGIKFFNSQGFKLSDQIEEKIEDIILNKKWDEVPHAQFDAIGRVNRVDLKKDYQEYLKSTLNGASFKGLKIVIDCANGAAYKIAPEVFEELGAEVVVINNQPDGTNINKECGSTHLKMLQQEVVKNRADFGIAYDGDADRTLFVDEEGNIVDGDKIMLLLAQNLKQQGRLSRNTLIVTVMSNMGLFVAAKELGIELEVTKVGDRYVLEKMLEGGYSIGGEQSGHIILLDFATTGDGILTSLQLTKLIRESGKKLSDLAKIMKVYPQVLVNAKVENGKKDLYSKDPVILEAIKKVEEKLNGKGRVLIRPSGTEPLIRVMIEGEDYEEIKKDAEALASLIESRLS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CAH1_SHEEP
Sequence: MASPDWGYDGENGPEHWCKLHPIANGNNQSPIDIKTSETKRDPSLKPLSISYNPATAKEIVNVGHSFHVNFEDSDNRSVLKGGPLPESYRLRQFHFHWGSTDDCGSEHLVDGATFSAELHLVHWNSAKYPSFADAASQADGLVVVGVLMKVGQANPNLQKVLDALKTVKTKNKKAPFTNFDPSVLLPSCPDYWAYFGSLTHPPLHESVTWIIFKETISVSAEQLAQFRSLLANAEGDKEVCIKQNYRPPQPLKGRTVKASF
What is the function of this protein?
Catalyzes the reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase 1, Carbonate dehydratase I, Carbonic anhydrase I, CA-I.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHFI_BACSU
Sequence: MKVTVIGCYGGFPAANEATSGYLFQSGDYSLLVDCGSAVLSKLFGYVPAEKLDAVVLSHYHHDHIADIGPLQFAKQVGSFLGKGEHTLPIYGHDADIEQFQKLTYKTHTKGIAYQPDQPLTAGPFTITFLKTIHPVTCYAMRITDGSHTVVYTADSSYQDSFIPFSKDADLLISECNFYADQDGTSAGHMNSLEAGRIAKEAGAGELLLTHLPHFGVHDNLRKEAKTVFNGEVNIAKSGFVWEG
What are the official names of this protein?
Probable metallo-hydrolase YhfI.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: HOATZ_BOVIN
Sequence: METRPSSSLSSPEESCEAFPQGLLVFTGSSDRDANLAKQFWIGASMYPHNESQLVLSRGSSQRLPVARPSRSSAPEKTYFQPFFLEESKSRDVTAETLKIQESEEKKKYLQKAKKRDEIIQLLRKQREERILKELISLPHKPKGKVHKAKKVISESDKEDQEEVKALD
What is the function of this protein?
Required for motile ciliogenesis and flagellar genesis by mediating the maturation of the glycolytic enzyme ENO4.
What are the official names of this protein?
Cilia- and flagella-associated protein HOATZ.
What is the protein family that this protein belongs to?
Belongs to the HOATZ family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium.
Protein: STXB1_BOVIN
Sequence: MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTTAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQKLLDTLKKLNKTDEEISS
What is the function of this protein?
Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity).  Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio.  Can interact with syntaxins 1, 2, and 3 but not syntaxin 4.  Involved in the release of neurotransmitters from neurons through interacting with SNARE complex component STX1A and mediating the assembly of the SNARE complex at synapic membranes (By similarity).  May play a role in determining the specificity of intracellular fusion reactions (By similarity).
What are the official names of this protein?
Syntaxin-binding protein 1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Protein: AMPA_CHLTR
Sequence: MVLLYSQASWDKRSKADALVLPFWMKNSKAQEAAVVDEDYKLVYQNALSNFSGKKGETAFLFGNDHTKEQKIVLLGLGKSEEVSGTTVLEAYAQATTVLRKAKCKTVNILLPTISQLRFSVEEFLTNLAAGVLSLNYNYPTYHKVDTSLPFLEKVTVMGIVSKVGDKIFRKEESLFEGVYLTRDLVNTNADEVTPEKLAAVAKDLAGEFASLDVKILDRKAILKEKMGLLAAVAKGAAVEPRFIVLDYQGKPKSKDRTVLIGKGVTFDSGGLDLKPGKAMITMKEDMAGAATVLGIFSALASLELPINVTGIIPATENAIGSAAYKMGDVYVGMTGLSVEIGSTDAEGRLILADAISYALKYCNPTRIIDFATLTGAMVVSLGESVAGFFANNDVLARDLAEASSETGEALWRMPLVEKYDQALHSDIADMKNIGSNRAGSITAALFLQRFLEDNPVAWAHLDIAGTAYHEKEELPYPKYATGFGVRCLIHYMEKFLSK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_RICCN
Sequence: MGKVIGIDLGTTNSCVAVMEGKEPKVIENAEGERTTPSIIAFANGEKLVGQSAKRQAVTNPRNTIYAVKRLIGRNFIDPMVRKDQGIVPYNIVKADNGDAWVEADNNKYSPSQISAFILQKMKETAENYLGDKVTQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGFEKSASKTIAVYDLGGGTFDVSILEIADGVFEVKSTNGDTFLGGEDFDTRILNHLIDVFKKENGIDLSKDPLALQRLKEAAEKAKKELSSAVTTDINLPYITADSSGPKHLNIKFTRAELEKLVDDLIEKTIEPCRKALQDAGFKASDIQEVVLVGGMTRMPKVQEAVKKFFGREPHKGVNPDEVVALGAAIQGGVLNKEVTDILLLDVTPLSLGIETLGGVFTRLIDRNTTIPTKKSQIFSTADDNQHAVTIRVFQGEREMAKDNKLLGQFNLEGIPLAPRGLPQIEVTFDIDANGIVHVSAKDKASGKEQKVTIQASGGLSDAEIEQMVKDAEQNADEDKKRKELIEAKNAADSLVYSTEKTLTEYGDKLSSDDKGAVEAALAALKAVLESEDTALIKEKTESLTAASMKIGEAMYKAQSESQPAAESATNDEKIVDADFQDVEKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SECB_MAGSA
Sequence: MTDAQTPSEDLPQLQVNMQYIKDLSFEIPGAPHSFIEMQGKNPEIPIHVDVNVGNVGANAYEVVLHLKIEALLDGKALFILELAYAGVFTLNLPEEQIHPVLLIECPRLLFPFARNIVADMTRDGGLPPLLLQPLDFVELYRARAAEMNAQQGQA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIPS_MOMCO
Sequence: DVTFSLLGANTKSYAAFITNFRKDVASEKK
What is the function of this protein?
Inactivates eukaryotic 60S ribosomal subunits.
What are the official names of this protein?
Ribosome-inactivating protein momorcochin-S, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: PP14D_HUMAN
Sequence: MLSSSPASCTSPSPDGENPCKKVHWASGRRRTSSTDSESKSHPDSSKIPRSRRPSRLTVKYDRGQLQRWLEMEQWVDAQVQELFQDQATPSEPEIDLEALMDLSTEEQKTQLEAILGNCPRPTEAFISELLSQLKKLRRLSRPQK
What is the function of this protein?
Inhibitor of PPP1CA.  Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 14D, Gastrointestinal and brain-specific PP1-inhibitory protein 1, GBPI-1.
What is the protein family that this protein belongs to?
Belongs to the PP1 inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCRP_PETMA
Sequence: CPCGRRRCCVRGLNVYCCF
What is the function of this protein?
May have microbicidal activities.  May inhibit corticotropin (ACTH) stimulated steroidogenesis and the microbial actions of the corticostatins.
What are the official names of this protein?
Corticostatin-related peptide LCRP.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CSPG5_MOUSE
Sequence: MGRAGGGGPDWGPPPVLLLLGVTLVLTAGAVPARETGSAIEAEELVRSSLAWESRANDTREEAGLPAAGEDETSWTERGSEMAAVGPGVGPEEALEASAAVTGTAWLEADGPGLGGVTAEAGSGDAQTLPATLQAPDEALGSSTMPPAIPEATETSGPPSPAVHDKPSVGPELPKEIPLEVRLNLGGSTPEPTFPLQGTLETQPASDIIDIDYFEGLDSEGRGADMGSFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLEEEEEEEEDKDTVGGGDLEDENDLLLPSQKPGVGPGTGQPTNRWHAVPPQHTLGMVPGSSISLRPRPGDPGKDLASGENGTECRVGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIAEGSHPNVRKFCDTPRVSSPHARALAHYDNIVCQDDPSAPHKIQDPLKSRLKEEESFNIQNSMSPKLEGGKGDQDDLGVNCLQNNLT
What is the function of this protein?
May function as a growth and differentiation factor involved in neuritogenesis.  May induce ERBB3 activation.
What are the official names of this protein?
Chondroitin sulfate proteoglycan 5, Acidic leucine-rich EGF-like domain-containing brain protein, Neuroglycan C.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Synaptic cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cell surface. Note=Partially enriched in lipid rafts (By similarity). Also detected in the endoplasmic reticulum and the Golgi (PubMed:10617623).
Protein: PSAC_BUXMI
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: NRDJ_LEPIN
Sequence: MKMNRHFTVPQNGESSTIQWTKRNSKITNPDGSKVFEANDILVPEDWSQVAVDILAQKYFRRKGVPKYLKKVQEDGIPEWLQKSIPDTEKLESLKPEDRFGGETSALEVFHRLAGCWTYWGYKYKYFSDEESAKIFYDEIVYMLATQMAAPNSPQWFNTGLNWAYGIDGKSQGHYYVDPSTGKLVKSTSAYEHPQPHACFIQSVDDDLVNEGGIMDLWVREARLFKYGSGTGTNFSNLRGENEPLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVCLDVDHPDIENFIDWKVTEEKKVASLVTGSMLNNRHLNAIMSACYEMEGEDRFNPKKNSSLKKTIQDAKKVLIPDNYIKRVIDLARQGYKEILFEELTTDWQSDAYNTVSGQNSNNSIRLTNEFMAAVEQDQPWNLYFRTEKEKAKVEGRKAKPSQTLRARELWEKISYAAWASADPGTQYHTTINEWHTCPEDGPINASNPCSEYMFLDNTACNLASANLQKFVNLETLNFDVEGFRYLCKLWTIILEISVTMAQFPSKEIAELSYKFRTLGLGYANLGSVLMVLGIPYDSQQAMAITGAISSIMHMTAYATSAEMAKEQGPFVGYAKNQKHMLRVIRNHRRAAYNAPSGDYEGLTITPIGINPAFCPSYMLKAAQEDADLALSLGEKYGFRNAQVTVIAPTGTIGLVMDCDTTGIEPDFTLVKFKKLAGGGYFKIINQSVPYGLKKLGYSPSEIEAIVNYCKGHATLNGAPVINTQALKEKGFTNEILEKVEASLPLAFDINFAFNKFNLGENFLTKNLGISKEIFDSPGFSLLEHLGFTKEDINKANDYVCGTMTIENAPFLKEKDYPVFDCANKCGKYGKRFLSYESHIRIMAAAQPFISGAISKTINLPEEAVIEDIKNAYFLSWKMMIKANALYRDGSKLSQPLNSVLELLNGIEIDDQEEIREATISKDPVQIAEKIVTKYISHRRKLPSRRAGYTQKAIVGGHKVYLRTGEYEDGQIGEIFIDMHKEGAAFRSLMNAFAISVSLGLQHGVPLEEYVDAFTFFKFEPNGIVSGNKHIKMSTSVIDYIFRELAITYLGRYDLGQVAPEDLRGDEIGSKRATAESNGQEKETLSSMTAVIEPTPKKEVETISYSQMISKEKPSSSPSGISLLEEVKLAKIKGYTGDSCSECGSFEMVRNGSCLKCMSCGSTTGCS
What is the function of this protein?
Catalyzes the reduction of ribonucleotides to deoxyribonucleotides.  May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen (By similarity).
What are the official names of this protein?
Vitamin B12-dependent ribonucleotide reductase, Ribonucleoside-diphosphate reductase NrdJ.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase class-2 family.
Protein: URE1_JANMA
Sequence: MSKISRQAYAEIFGPTTGDRLRLADTELFIEIEKDFTTYGEEVKFGGGKVIRDGMGQSQRNYKDVMDTVITNAVIVEHWGIVKADIGLKGGKIAGIGKAGNPDIQPDVTMAIGGATEIIAGEGMIVTAGGVDTHIHFICPQQIEEALMSGVTTMIGGGTGPAVGTAATTCTPGPWHIHSMLSAADAFPMNLGFLGKGNVSLPTPLEEQIHAGAIGLKLHEDWGSTPAAIDNCLSVADRLDVQVAIHSDTLNEGGFLEHTLAAFKDRTIHTFHTEGAGGGHAPDIIAAVGQANVLPSSTNPTRPFTVNTLDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILHDIGAISMMSSDSQAMGRVGEVIMRTWQTAHKMKVQRGSLAGDPARNDNFRVKRYIAKYTINPAITHGISHVVGSLEVGKVADIVLWKPAFFGVKPSMILKSGMIAAAQMGDPNASIPTPQPVHYRMMFGAYGGGLKTSMTFVSQSAFDAGIGDMLKLNKPVVAVKNMRHLRKRDMIHNSATPKMEVDSETYEVRADGELLVCEPAKILPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_HERAR
Sequence: MFDVLVYLYETYYRPDACPDSEALVKKLSAVGFEEEEITKALGWLTALAETTNELSDSYPHQTAFSFGTRIYVSQETDVLGTPAVGFIQFLEAAKLINPIQREIVIERALAAGETPISLEKLKVIVLMVLWSQGKEPDGLIFDELFLDDDDAAPRILH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.