PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_ACIF5
Sequence: MATRDYYEVLEISRTADDGEIKKSYRRLAMRYHPDRNPDDASAEERFKEISAAYEVLSDPQKRQAYDRFGHAGVNGGGGGPGAGFGGGGGGFGDVFSDLFEQAFGGGFRGQDSGRGADLRYELELTLEEAALGKEVTIQIPSSATCEVCRGSGAKPGSAVEDCATCGGRGQVRMVQGFFSVTRPCPQCNGSGKVIKEPCTNCHGHGRVRRNRDLQVKVPAGVDTGDRIRLNGEGEAGERGGPAGDLYIQVRVLPHALFERDGDDLHCAVPVQFTTMAMGGELEVPTLTGRAKVQIAPGTQSGAVFRLRGKGIKGVRSKLNGDLHCQLQVEVPVHLSARQKELLEEFAREGGDNIQHPQQESWWNKAKDFFDRMGL
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U17LN_HUMAN
Sequence: MEDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMEKACLPGHKQV
What are the official names of this protein?
Putative ubiquitin carboxyl-terminal hydrolase 17-like protein 23.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP17 subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum.
Protein: EX7L_AGRFC
Sequence: MSDIFSHTALSNLAEFSVSELSGSIKRTVETAFEQVRVRGEISGYRGPHSSGHAYFSLKDDRARIDAVIWKGTFSRLKFRPEEGMEVIATGKITTFPGSSKYQIVIESLEPAGAGALMALLEDRRRRLAAEGLFDSARKRPLPFMPRVIGVVTSPTGAVIRDILHRISDRFPVHVVVWPVKVQGEGSGEEVANAIRGFNALKPGGDIARPDVLIVARGGGSLEDLWSFNDEIVVRAAAESEIPLISAVGHETDTTLIDYAADVRAPTPTGAAEMAVPVRAELEAQLSGLAARLSGSVSRQMDNRRQGVRALVRALPSLDQLLALPRRRFDEAASGLGRGLELTTLNKRRAFERSASGLRPETLLNGLKHHRQRITERMHRAETLVERRLLQGKGRVDSFDSALRSLPARLLGQLERQKERVVTAARRADTAVLHRMAQNRSGLAAHDRILQSLSYKNVLNRGYAVIRDEENRPLTRAAAIASGAAVSMEFADGRVSAITTGEGTPAPETAAAPKKKPAKPASSDPGNQGNLF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAE_SHIFL
Sequence: MLSKQIPLGIYEKALPAGECWLERLRLAKTLGFDFVEMSVDETNERLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYPLMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVVKACDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: RL24_EHRCR
Sequence: MGMKIIAGDDVIVISGKDKGKMGKVIKVLKKKHCGKDVSFAIVSGVNVCRKSVKATQKSDGGIISVEKPINLSNIALFDSTLGIQTRVGYKFIGEKKVRFMKSSGKVIE
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: P5CR2_MOUSE
Sequence: MSVGFIGAGQLACALARGFTAAGVLSAHKIIASSPDMDLPTVSALRRMGVNLTRSNKDTVRHSDVLFLAVKPHIIPFILDEIGADVQERHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTNTPVVVREGATVYATGTHALVEDGKLLEQLMSSVGFCTEVEEDLIDAITGLSGSGPAYAFMALDALADGGVKMGVPRRLAVRLGAQALLGAAKMLLDSEDHPGQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKVSPAALKKTLLDRVKLESPTVSTLAPPSSGKLLTRNPAQGSKKE
What is the function of this protein?
Housekeeping enzyme that catalyzes the last step in proline biosynthesis.  In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+).  Can utilize both NAD and NADP.  Has higher affinity for NADP, but higher catalytic efficiency with NADH (By similarity).  Involved in cellular response to oxidative stress (By similarity).
What are the official names of this protein?
Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: AFF3_HUMAN
Sequence: MDSFDLALLQEWDLESLCVYEPDRNALRRKERERRNQETQQDDGTFNSSYSLFSEPYKTNKGDELSNRIQNTLGNYDEMKDFLTDRSNQSHLVGVPKPGVPQTPVNKIDEHFVADSRAQNQPSSICSTTTSTPAAVPVQQSKRGTMGWQKAGHPPSDGQQRATQQGSLRTLLGDGVGRQQPRAKQVCNVEVGLQTQERPPAMAAKHSSSGHCVQNFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKLKSSSETSVHCTSYRGVPASKPEPARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMTWLPPLSAIQAPGKVEPTKFPFPNKDSQLVSSGHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQRTALRALSDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPHFSSPEAEPASSNKWQLDKWLNKVNPHKPPILIQNESHGSESNQYYNPVKEDVQDCGKVPDVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPPAVPCAPAENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDLESEQEEYPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTLVPFGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSDTPAEKALPKSKRKRKCDNEDDYREIKKSQGEKDSSSRLATSTSNTLSANHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSKKPKADSQLQPHGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPRSADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSETVELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGLHWLRNSAHLS
What is the function of this protein?
Putative transcription activator that may function in lymphoid development and oncogenesis.  Binds, in vitro, to double-stranded DNA.
What are the official names of this protein?
AF4/FMR2 family member 3, Lymphoid nuclear protein related to AF4, Protein LAF-4.
What is the protein family that this protein belongs to?
Belongs to the AF4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXB_SULSY
Sequence: MKKIFLSVGEISGDNYASELAKHLKEYQITGITGPKMRAIGVKPVANLEDISVVGLTEALSKYKKIKEVFKQSVQALKSGVDLLIVVDFPGFNIKLLKEAKKLGIKTVYFISPQVWAWGSGRVKEIVENTDLLISILPFEEEIYKPYVSDKFKFAYVGHPLLDIIKIYENEDSFKQKLNIPKNKRIIGLLAGSRESEVNVILPILIEAARLLTKTFDDLHFVIPATVNMVDRVLEKVNFSLPITVITSNLSDKNLPKFENPSYEVMKNAVFSIITSGTATLEAAIIGNPFIIVYKVSPITYFIGKKLVKINYLGLPNIIAGNEIVPELLQDRCNPLDIANKTLEFLTDKNLYKTQKRNLEIVRKSLGKKGAIERASNLIRTLLEKGQA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: KLHL1_MOUSE
Sequence: MSGSGRKDFDVKHILRLRWKLFSHPSPASSSPAGGSCLQQDSGGGSFEHWGPSQSRLLKNQEKGSVSAFWKKPSSSSSSSSSSSSSASSSPFNPLNGTLLPVATRLQQGAPGQGTQQPARTLFYVESLEEEVVTGMDFSGPEDKGLALKELQAEPASSIQATGEGCGHRLTSTNHSLTPQSDLDSSSSEEFYQAVHHAEQSFRKMENYLKQQQLCDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAKQEEIKMEGIDPNALWDLVQFAYTGCLELKEDTIENLLAAACLLQLPQVVEVCCHFLMKLLHPSNCLGIRAFADAQGCIELMKVAHSYTMENIMEVIRNQEFLLLPAEELHKLLASDDVNVPDEETIFHALMMWVKYDMQRRCSDLSMLLAFIRLPLLPPQILADLENHALFKNDLECQKLILEAMKYHLLPERRTLMQSPRTKPRKSTVGTLYAVGGMDNNKGATTIEKYDLRTNLWIQAGMMNGRRLQFGVAVIDDKLFVIGGRDGLKTLNTVECYNPKTKTWTVLPPMSTHRHGLGVTVLEGPIYAVGGHDGWSYLNTVERWDPQSQQWTYVASMSIARSTVGVAALNGKLYSVGGRDGSSCLSSMEYYDPHTNKWSMCAPMCKRRGGVGVATCDGFLYAVGGHDAPASNHCSRLLDYVERYDPKTDTWTMVAPLSMPRDAVGVCLLGDRLYAVGGYDGQTYLNTMESYDPQTNEWTQMASLNIGRAGACVVVIKQP
What is the function of this protein?
May play a role in organizing the actin cytoskeleton of the brain cells.
What are the official names of this protein?
Kelch-like protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS17_CHLCV
Sequence: MASEERGLRKTKVGVVVSSKMDKTVVVRVERIYSHPQYAKVVRDSKKYYAHNGLDVSEGDKVKIQETRPISKLKRWRVVERVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DNAK_LISMC
Sequence: MSKIIGIDLGTTNSAVAVLEGGEAKIIPNPEGARTTPSVVGFKNGERQVGEVAKRAAITNPNTISSIKRHMGTNYKETIEGKDYSPQEISAIILQYLKSYAEDYLGETVDKAVITVPAYFNDAQRQATKDAGKIAGLEVERIINEPTAAALAYGMDKTETDQTILVFDLGGGTFDVSILELGDGVFEVHSTAGDNELGGDDFDKKIIDYLVAEFKKDNGIDLSQDKMALQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEVTLTRAKFDELTHDLVERTIAPTRQALKDANLSASDIDQVILVGGSTRIPAVQETIKKELGKEPHKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVMTTLIERNTTIPTSKSQTFSTAADNQPAVDIHVLQGERPMAKDNKTLGRFQLADIPPAPRGIPQIEVSFDIDKNGIVTVRAKDLGTGKEQNIVIKSSSGLTDEEIEKMVQDAEANAEEDKKNKENAELRNNADQLVFTVDKTLKELEGKVEEEEVKKAEAARDELQEALKGEDFEAIKEKTESLNEIVQNLSVKLYEQAAAEQQAAGGAEGQEAPQNDDVVDAEFEEVNDDDKENK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SBDS_HUMAN
Sequence: MSIFTPTNQIRLTNVAVVRMKRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKLKPLIKVIESEDYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLKDVEEGDEKFE
What is the function of this protein?
Required for the assembly of mature ribosomes and ribosome biogenesis.  Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export.  Required for normal levels of protein synthesis.  May play a role in cellular stress resistance.  May play a role in cellular response to DNA damage.  May play a role in cell proliferation.
What are the official names of this protein?
Ribosome maturation protein SBDS, Shwachman-Bodian-Diamond syndrome protein.
What is the protein family that this protein belongs to?
Belongs to the SDO1/SBDS family.
Protein: RECR_ALKMQ
Sequence: MNYYSAPIAKLIDEFSKLPGIGRKTAQRLAFHVISMGYEDAEKLSNSIIEAKKSIKYCRICTNLTDKEVCNICSDPNRKKSVICVIEDPRDVVAMERTREFKGQYHVLHGAISPLEGIGPEEINIKELLIRLQEHPVEEVILAMNPNIEGEATAMYIGKLLKPIGIKVSRIAHGIPVGGDLEYADEVTLSKALEGRREI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: YAAA_ECO27
Sequence: MLILISPAKTLDYQSPLTTTRYTLPELLDNAQQLIHEARKLTPPQISSLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALAAQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRFIIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: FUB12_GIBM7
Sequence: MPLPSRASSTPKISKACVPCRTRKIKCNAAVVGLPCGSCVSRECPDECVLSARKRRTVKGRNAETPRSRKNIPDTNGSVLSPRQQQLPTNVSRQATDSSHSDPVEESIHASHTGSSLRNDTPHSRDRRPPGQTQADLLYLNILQDTVNDTSAAQTDASDHQSNDEPDDSFNSQIHHWNPPPQLDDVDNEYLAKKKVFELPPPRFMENIVKAYFDYVHPFAPILNRTDFIQSYRSGSCCLFLLHAVAAAASLYVTHDVLIGCGYQDRSTAQASFFSKAKLFHDFHCQGDPLSMLQGSMILGAIILDHPSDRDFQYWFHNSVRRASKMGVQNACLRDDGSQKLYRRIWWVLHNRDIFHFFINTQNMRLLANAPPIRPLTEADWETEDMEQWSGILSPISQAQKVSLIAQCELAQIFGNVMSVVTSSTPSAEEIHKRILPLDAWRTSLPERMQLMASFANGEKYHLEALTTSYRFECIMCRLLRRGRWQMSDGGLREWAQQRFRSAIFELDTIVKRVMINNTIQKLPTTFITTITALLALHIESALDAAESSLIRSMARISVQHTMLALDQIRDTPAIKRALPAFEIVLSKNKLYPMSTSDTEQISTIQTIPQDQTLSDGQILQPPPTDMTLPQDDQSFLYGDFIGFDFLDRWQMEQLDFTGIY
What is the function of this protein?
Transcription factor that is involved in the formation of the two Fusaric acid derivatives, dehydrofusaric acid and fusarinolic acid, serving as a detoxification mechanism (By similarity).
What are the official names of this protein?
Fusaric acid cluster transcription factor FUB12, Fusaric acid biosynthesis protein 12.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASTD_ECO24
Sequence: MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACRAARAAFPRWARLSLAERQVVVERFAGLLERNKGELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAWQQLEAMGGRTLLAPRLLQSETSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEAILMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: NECA3_BOVIN
Sequence: MACAGLLTVCLIRPPAPEPPRPPAPAPAAGPAGHALFQDVFRRADKNDDGKLSFEEFQNYFADGVLSPGELRELFSGVDGHPADNLETEKLCDYFSEHLGVYRPVLAALESLNCAVLTAMDTTKLEYERASKVDQFVTRFLLRETVSQLQALQSSLEGASDTLEAQAQGPRSDEERVEVPSRPRGSRWAGRRALRSVSRSSTWSPGSSNTGQSSEAEMQWRLQINRLQELIDQLECKAPRLEPLHEEELTKGPSSHILVAQRQVQVAEEALQDFHHALCCYVDFTGSQSHCLHVSAQKMLDKASFTLYEFWQDEASWRRHQQSACSKAFQRILIDHLRAPDTLTTVFFPASWWIMNNN
What is the function of this protein?
Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta (By similarity).  May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3 (By similarity).
What are the official names of this protein?
N-terminal EF-hand calcium-binding protein 3, Amyloid-beta A4 protein-binding family A member 2-binding protein, X11L-binding protein 51.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: LPXK_SHIBS
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGSKAESYPLLLSADTTTAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSASVSAEQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTSLASGN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: TIM50_EMENI
Sequence: MLRRAILPLTRPSGLVSAPRLSALPVSHSRCYAKGSKPKTPYKLPESVKSSKPEQPAKPSQQEQYAAEQAEFETTSDPQANTANTTSQASSSPESSPSQSEQDAPQRPLPDLTQGIPSTLAAELEARSKKSGSGTLNLTEDPSRFEEDYSDDGRGDIPKGGYESSLDRKRARMAKLMYALFLLGSVGGMAYLGRNWDTVEEENAHPDVPSGWSFGLWYNRIKARMGDFTSYYKDPAFPKLLPDEDPNLRQPYTLVLSLEDLLVHSEWSREHGWRVAKRPGVDYFLRYLNQYYELVLFTSVPSMMADQVLRKLDPYRIIRWPLFREATRYKDGEYIKDLSYLNRDLSKVILIDTKEEHARLQPENAIILDKWNGNPKDKTLVALIPFLEYLAGMGVDDVRTVLKSFEGQSIPIEFAKREKAMRERFEKELAEEQKKRPRSGMGSLASALGLKSSARTLDGEQLPSAGLQEGKMLWDQIRERGQKNYELIEKEIRENGEKWLAEMAAEEEKLRQEQMESMKGSLTGFFGGGKKE
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim50.
What is the protein family that this protein belongs to?
Belongs to the TIM50 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SSB_ECOLI
Sequence: MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEVVVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSAPAAPSNEPPMDFDDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.  Acts as a sliding platform that migrates on DNA via reptation.  SSB or its 10 C-terminal amino acids stimulates the ATPase activity of RadD (PubMed:27519413).
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB, Helix-destabilizing protein.
Protein: MNMC_BORPD
Sequence: MSSYSPLVPPAAGFDADGRFRSVAYGDVYHSLSGALGQAEHVFLRGNGLPQRWRGRQAFTVCETGFGLGLNFLALWDAWRNDPARPRCLHMVSIEAHPFARDALRDWLRQLAPDILQGLAGQLADQWPACLPGLHRLEFEGGAVTLTLAFGAASALAPHLRARVDAYFLDGFAPDRNPELWQPALMRDLARMAAPDATLATWACAGSVRQALRDAGFRVRKQPGYGGKWHMTVGVRESAQPEAPADAWALARAADGEGQDEVVVVGGGLAGAGIAQALALRGRPVCVIDAAGPASAHAGHVAAALTPVIARDDNPRARLSRAGSQRALARWAGLRPGAAPRRCGTLQLERDAGRSAALAETLQQLQFPADWVRAVDRDEAAGLAGVPLARGGVFFADGLLVQPAALIPALLGMPGVRRVAGCAAVLRRVAHGWQVLDDAGQLLGQGATVVLANAFGAQALLRDSGLLDPLPRVAQMHALAGEITLLPGQGLGGGPRCIVGGEGYLLPPVDGWCVAGSTYEHGAATARVGPAGQQTNLGKAAGLLGGLPAAWAALAPGQLPGWAGWRAVLPGRLPAVGPLGHAPGVWLAAGYASRGLSWSALAGDLIAACLHGEPLPLPADLLAAVAPR
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLYC_RICRS
Sequence: MLKSSKKEDSSKKNQNNKLIFTVRKLFSPIKNFFRKTKTPDNFFGVIKRLKINSQKMTLDERNILANLLELEDKTIEDIMVPRSDIAAIKLTTNLEELSESIKLEVPHTRTLIYDGTLDNVVGFIHIKDLFKALATKQNGRLKKLIRKHIIAAPSMKLLDLLAKMRRERTHIAIVVDEYGGTDGLVTIEDLIEEIVGRIDDEHDQQLDSDNFKVINNSTIISNARVEVEVLEEIIGEKLHNDYDEFDTIGGLVLTRVSSVPAIGTRIDISENIEIEVTDATPRSLKQVKIRLKNGLNGQ
What are the official names of this protein?
Hemolysin C homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family. Hemolysin C subfamily.
Protein: SYH_KORCO
Sequence: MVSIPRGFRDFPPPMMILRKRVLSKIEEIFRRYGFDPIETPSLEYWETVKGKLGEEAENKLMFIFPDFFSKEWYTLRYELTFPLARYVAMHPETPLPFKRYHIGNVWRHEEPQKGRYREFLQCDADIVGSPYPEADAEVISVNIDAMKSFDFENFRVRLNDRRLLTGVFEEELGINNPFPIYRAIDKLDKIGVDGVKGELARLGAHESLIGRIMELISTRGSFNEISNTFRRIENDKVKVALDHLEEIFSIVSDDRLVFDLSLVRGLDYYTGPVFETSVSEPRIGSLAGGGRYDRLIGLYSGKDVPATGVSLGVERLIDAGLELGIFDLSERSYTDVFIVSVRRENWRYAWRISRILRERGFSTSLDLMRRSQSAQREYANKIGAKVIAFVGPSEEETETVTLYSRDLRKTVKISELIDSLREFLSVS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STF1_NOTEU
Sequence: MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQNCKIDKTQRKRCPYCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGFKLETGPSMGPPPQTDYPLAPALHPGAKGLAPAPPAGPPGDYERGPYGPPGVPMAVPTHGPLAGYLYPAFPGRAIKSEYPEPYASPHEPAPPYGYPEPYPSGPGLPGVPELILKLLQLEPDEGQLKARILACLQEPSKGRPDRPTPFGLMCKMADQTLFSIVEWARSCVVFKELEVADQMKLLQNCWSELLVFDHIYRQIQHGKEGSILLVTGQEVDLSTVAAQAGSLLHSLVLRAQDLVQQLHSLQVDRQEFVCLKFLILFSLDVKFLENHGLAKDAQEKANSALLEYTMCHYPHCGDKFRQLLLRLAEVRSLSMQAEEYLYHKHLGGEVPCNNLLIEMLHAKRT
What is the function of this protein?
Transcriptional activator.  Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues.  Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B.  Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes.  5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1.  The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity.  Binds phosphatidylcholine and phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3.  Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (By similarity).
What are the official names of this protein?
Steroidogenic factor 1, SF-1, STF-1, Nuclear receptor subfamily 5 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACCD_LIBAP
Sequence: MNWITNFVRPRINSVFGRRAIPENLWVKCPETGAMVYHKDLKENQWVISSSDFHMKIPAKERLKFLFDNAKYCLLDQPQVCQDPLKFRDNKKYIDRLKENRSKTGLIDSIVSAVGNVRDFKLVAVVHEFSFIGGSIGIAAGEAIVKSCERAIAEKCPLVMFTASGGARMQEGILSLMQLPRTTIAINMLKDAGLPYIVVLTNPTTGGVTASYAMLGDIHLAEPGAEIGFAGRRVIEQTVREKLPDGFQRSEYLVEHGMIDRIVHRHDIPEVVSSLCKILTKSVQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.