PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_CORU7
Sequence: MCRAVAGVTRFVFTLALGVGSAHVTHAMKKKTSVSEQPEQRTYEVRTFGCQMNVHDSERLSGLLEDSGYQPAANGEEPDVLVFNTCAVRENADNRLYGTLAMVKPMKDRNPGMQIAVGGCMAQKDKDAVVDRAPWVDVVFGTHNIGSLPTLLERSAHNQRAEVEILDSLEEFPSVLPAKRESAYSGWVSVSVGCNNTCTFCIVPSLRGKEQDRRPGEILAEVQALVDQGVQEVTLLGQNVNAYGVNFADEDLPRDRGAFAKLLRACGEIEGLERLRFTSPHPAEFTDDVIDAMAETPNVCPQLHMPLQSGSDRILKEMRRSYRSKKFLGILDKVRERIPHAAITTDIIVGFPGETEEDFQATLDVVEKARFSCAFTFQYSPRPGTPAATMPDQIPKAVVQERYERLIALQERIQAEDNKELVGTTQELLVQETGGRKDAQRHRMSGRARDGRLVHFTPSEDVRPGDIVEVTITDARPFFLIADGPLVNHRLTKAGDMSGAGQTPTTAPIGVSLGVPTIGIKPQADATAAPKNVHEGCGCD
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYSC_RABIT
Sequence: MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRADNLNKLKNLCSKTIGEKMKKKEPVGDDESIPENVLNFDDVTADTLTNLKVSQIKKVRLLIDEAILKCDAERIKLEAERFESLREIGNLLHPSVPISNDEDADNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLRNRGYTPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMIATAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGIIVPEKLKEFMPPGLQELIPFVKPAPIDQEPSKKQKKQHEGSKKKAAARDVTLENRLQNMEVTDA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser).  Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).  In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC.  Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16).  Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA.
What are the official names of this protein?
Serine--tRNA ligase, cytoplasmic, 62 kDa RNA-binding protein, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, but a minor proportion is also found in the nucleus.
Protein: ADEC_DEIDV
Sequence: MTQWAMTESLEDRRRLVRVARGLEEGDLLVRGARVAQPVTREILEADVLIADGRVAVLGGTGDGLQAARVVEARGAFLAPGFIDGHVHIESSLLTPAGFARAVLLRGTTGVVAEPHEVVNVLGPQGLEWMLEAGRRSGLRVWASAPSCAPASGFEAGGARVGTAEVRQMLGQPGVLGLAEMMNYPGVLGGDEEVWAVIQAGRATGRRLDGHAAGVRGRDLQAYAAAGLHSDHEATTPEEARERLRAGLWLMVREGSAARNLQALLPVLRERPRRAMLVSDDVSVDELLELGHLDRLLRACVAGGLDPLDALALVTCNPAEYWGLHDVGLIAPGHLADFVLLRDLQSFEVLETFVGGAEAQPGELTPPLSGGGVHLGQGWDAATFEVPPGWPVLGIHAEQITTSREPEGSGDARLIVADRYGRGEWSACWTAGSGLTGGTLGISVLHDAHHAAFLGGSDTDVRMAGRALEALGGGLVVVSDGEVRASLPLPFAGLMTGEAPQEAAAGLARVTAATRALGCTLPYPVTTLSFLGLTVIPSLKLTPRGLLDVEAWQLVPSR
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: CELF1_PONAB
Sequence: MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILWGPDGLSRGCALVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY
What is the function of this protein?
RNA-binding protein implicated in the regulation of several post-transcriptional events.  Involved in pre-mRNA alternative splicing, mRNA translation and stability.  Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing.  Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition.  Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs.  Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB.  Promotes exclusion of exon 11 of the INSR pre-mRNA.  Inhibits, together with HNRNPH1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast.  Increases translation and controls the choice of translation initiation codon of CEBPB mRNA.  Increases mRNA translation of CEBPB in aging liver.  Increases translation of CDKN1A mRNA by antagonizing the repressive effect of CALR3.  Mediates rapid cytoplasmic mRNA deadenylation.  Recruits the deadenylase PARN to the poly(A) tail of EDEN-containing mRNAs to promote their deadenylation.  Required for completion of spermatogenesis.  Binds to (CUG)n triplet repeats in the 3'-UTR of transcripts such as DMPK and to Bruno response elements (BREs).  Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.  Binds to AU-rich sequences (AREs or EDEN-like) localized in the 3'-UTR of JUN and FOS mRNAs.  Binds to the IR RNA.  Binds to the 5'-region of CDKN1A and CEBPB mRNAs.  Binds with the 5'-region of CEBPB mRNA in aging liver (By similarity).  May be a specific regulator of miRNA biogenesis.  Binds to primary microRNA pri-MIR140 and, with CELF2, negatively regulates the processing to mature miRNA (By similarity).
What are the official names of this protein?
CUGBP Elav-like family member 1, CELF-1, Bruno-like protein 2, CUG triplet repeat RNA-binding protein 1, CUG-BP1, CUG-BP- and ETR-3-like factor 1, RNA-binding protein BRUNOL-2.
What is the protein family that this protein belongs to?
Belongs to the CELF/BRUNOL family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=RNA-binding activity is detected in both nuclear and cytoplasmic compartments.
Protein: LEF4_NPVAC
Sequence: MDYGDFVIEKEISYSINFSQDLLYKILNSYIVPNYSLAQQYFDLYDENGFRTRIPIQSACNNIISSVKKTNSKHKKFVYWPKDTNALVPLVWRESKEIKLPYKTLSHNLSKIIKVYVYQHDKIEIKFEHVYFSKSDIDLFDSTMANKISKLLTLLENGDASETLQNSQVGSDEILARIRLEYEFDDDAPDDAQLNVMCNIIADMEALTDAQNISPFVPLTTLIDKMAPRKFEREQKIVYGDDAFDNASVKKWALKLDGMRGRGLFMRNFCIIQTDDMQFYKTKMANLFALNNIVAFQCEVMDKQKIYITDLLQVFKYKYNNRTQYECGVNASYAIDPVTAIECINYMNNNVQSVTLTDTCPAIELRFQQFFDPPLQQSNYMTVSVDGYVVLDTELRYVKYKWMPTTELEYDAVNKSFNTLNGPLNGLMILTDLPELLHENIYECVITDTTINVLKHRRDRIVPN
What is the function of this protein?
Component of the viral DNA-dependent RNA polymerase that catalyzes two reactions involved in viral RNA cap formation: an RNA 5'-triphosphatase that hydrolyzes the gamma phosphate of triphosphate-terminated RNA and a guanylyltransferase that reacts with GTP to form a covalent protein-guanylate adduct.  Therefore plays an essential role in late and very late gene expression.
What are the official names of this protein?
DNA-dependent RNA polymerase subunit LEF-4.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-4 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Preferentially in the host nucleus and associated with the virogenic stroma.
Protein: Y4505_VIBPA
Sequence: MDIVVDSHTHTIASGHAYSTILENALAAKNKGLKLLCTTDHAPEMPGAPHYWHFNNQRILPRFLHEVGILRGVEANTLNVKGEIDLPLSSDQHLDWVIASFHEPVFRPATEAEHTAALINVIKSGRVDVLGHLGNPNYPFDMEQVLRCAKSHNVAIEVNNTSLTGKSRKGSDARCDQIVALGKEIGVYFSTGSDAHFCEEISKLDLAIELLEKHGVEKDKILTTSTRRFLKFLLLRGKPRIPEFDAFY
What are the official names of this protein?
Probable phosphatase VPA0505.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: TILS_FRATH
Sequence: MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLASIPHYKELHHGGVLRPLLKYSKIDIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 065L_FRG3G
Sequence: MRGLEAPGAVGPTGPSGAPGSQGPDGDVGGMGPEGPKGDDGPVGPKGPQGAAIF
What are the official names of this protein?
Putative collagen-like domain-containing protein 065L.
Protein: NU4LC_CHAVU
Sequence: MILQHILILSSFLFCLGIFGLITSQNMVKILICLELIFNAVNLNLVIFCKFFDSSAIIGNLFGLFIIAIAAAEAAIALAILLAMYRNRRSIRIDRFNILK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PYRE_XANCB
Sequence: MTDHRTRFLQLALDADALRFGEFTLKSGRLSPYFFNAGRFDSGAKTAQLAQCYADAIDAAGVEFDLLFGPAYKGIPLATALACAYAGRGRDLPLAFNRKEAKDHGEGGTLIGAPLQGRKVLIVDDVITAGTAIREALGIIRAAGGTPSGIVVALDRQEIASEQDRRSAAQAVAAEAGIPVIAVANLADLLAFAAGNADLVGFREPLLAYRGRYGTDTTG
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TFR1_PIG
Sequence: MMDQARSAFSSLFGGEPLSYTRFSLARQVDGDNSHVEMKLAADEEENVDSNTRSNHIGVAKPKRLNGYVCYGIIAVITFFLIGFMIGYLAYCKRVESKTDCKTLVPTEPSETEETETFEAENFPQTPRLFWADLKILLSKGLDTTDFTRTIKMLNEDYAPREAGSQKDESLGFFIENQFREFKLSKVWHDEHFVKIQVKGSNAENSVTLVNTDSNSLVYPVESPEGYVAYSKATTVTGKLIFANFGTKKDFEDLKMPVNGSLVIVRAGKITFAEKVANAQSLDAIGVLIYMDRANFPIINADVPVFGHAHLGTGDPYTPGFPSFNHTQFPPSQSSGLPNIPVQTISRAGAEKLFGNMEQDCPLTWRTDFPCKLVSSPSKNVKLTVNNVLKEIKILNIFGVIKGFEEPDRYVIVGAQRDAWGPGAAKSSVGTSLLLNLAQILSDMVIKGQFKPSRSIVFASWSAGDFGAIGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASPLLYSLIEKMMQDVKNPVTGQSLYRDSNWINKVEKLSFDDAAFPFLAYSGIPAVSFCFCEDTDYPYLGTTMDTYDVLSKRVPQLNRMARAAAEVAGHLVIKLTIDFELNLNYEMYNDKILSFVREMNQFRVDIREMGLSLQWLYSARGDFFRATSRLTSDYRNVETRDKFVMREINDRIMKVEYHFLSPYVSPRESPFRHIFWGSGSHTLSALVEHLKLRQKNSSAFNQTLLKNQLALATWTIQGAANALSGDIWDIDNEF
What is the function of this protein?
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (By similarity).  Endosomal acidification leads to iron release.  The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.  Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity).  Positively regulates T and B cell proliferation through iron uptake (By similarity).  Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway (By similarity).  When dietary levels of stearate (C18:0) are low, promotes activation of the JNK pathway, resulting in HUWE1-mediated ubiquitination and subsequent degradation of the mitofusin MFN2 and inhibition of mitochondrial fusion (By similarity).  When dietary levels of stearate (C18:0) are high, TFRC stearoylation inhibits activation of the JNK pathway and thus degradation of the mitofusin MFN2 (By similarity).
What are the official names of this protein?
Transferrin receptor protein 1, TR, TfR, TfR1, Trfr.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Melanosome.
Protein: T178A_DANRE
Sequence: MEKRALVTAISLSMSLLALMLLVTAIFTDHWYETDTRRHKENCDQYGSESNDQKNREMPIYHLPLVDSGNAKRNLALMKPIHVGSREEELLENWRAILGMGILETECGRPLFSTYSGLWRKCYFQGMDRDIDKLILKGIAERCTSVKYHFSQPIRLRNIPLNLTRTIQQDEWHLLHLRRITAGFLGMAAAVMLCGSIVAAVGFFWEESLTQHVSGLLFLMAGIFCTISLCTYAASVSYDLSRNPPFIYGLPSDVDHGYGWSIFCAWVSLGLTVASGCICTTYPFLSRTKALRSKTARESSV
What is the function of this protein?
May act as a negative regulator of osteoclast differentiation.
What are the official names of this protein?
Transmembrane protein 178A.
What is the protein family that this protein belongs to?
Belongs to the TMEM178 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YE91_HELPJ
Sequence: MEIRNIKEFEKASKKLQKDTLKIALALLFLIGAALLALIFGQANSKGLLLIFAAVIGGYMAMNIGANDVSNNVGPAVGSKAISMGGAILIAAVCEMLGAIIAGGEVVSTIKGRIVSPEFINDAHVFINVMLASLLSGALWLHVATLIGAPVSTSHSVVGGIMGAGMAAAGMSAINWHFLSGIVASWVISPLMGALIAMFFLMLIKKTIAYKEDKKSAALKVVPYLVALMSLAFSWYLIVKVLKRLYAVGFEIQLACGCVLALLIFILFKRFVLKKAPQLENSHESVNELFNVPLIFAAALLSFAHGANDVANAIGPLAAISQTLEDASSPMGSTLNSVPLWIMVVGAAGIALGLSLYGPKLIKTVGSEITELDKMQAFCIALSAVITVLLASQLGLPVSSTHIVVGAVFGVGFLRERLREQSRRRFARIRDNIVAAHFGEDLEEIEGFLERFDKANLKEKSLMLESLKKSKNTAIALELKKKEKKSLKKVYKEEVIKRSILKKIVTAWLVTVPVSALLGALLFVALGFIEKYF
What is the function of this protein?
Potential transporter for phosphate.
What are the official names of this protein?
Putative phosphate permease jhp_1384.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MBP_RABIT
Sequence: ASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFSSDRGAPKRGSGKDHAARTTHYGSLPQKSGHRPQDENPVVHFFKNIVTPRTPPPSQGKGRGTVLSRFSWGAEGQKPGFGYGGRAADYKSAHKGLKGADAQGTLSRLFKLGGRDSRSGSPMARR
What is the function of this protein?
Is, with PLP, the most abundant protein component of the myelin membrane in the CNS.  Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers.  Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).
What are the official names of this protein?
Myelin basic protein, MBP, Myelin A1 protein, Myelin P1 protein.
What is the protein family that this protein belongs to?
Belongs to the myelin basic protein family.
What are the subcellular locations of this protein?
Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.
Protein: COBS_CLOK5
Sequence: MKELLNDFFLILQLLTRIPVNRNLLCRRENFRRGASFMPLVGVIVGGIQWIIYKLCIIIFSLNVSIVIVILAGIVLTGALHVDGLGDMCDGFFSFKEKGKIIEIMKDSRIGTYACLAIIIDILLKYSFFCSIVPSFSLIIIIAPVMSRFSIVFIAFIGKPAKSTGSGNLFVENIGKWQLFWAAFITVITLFFLMNMNFIYVIILIFAGLFMSFLFNVFCNRKAGGLTGDLLGANNEIVEILTMVMLCVIITK
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPD_BRADU
Sequence: MSLSALESTINSAFDARDGISTSTKGEVREAVDQVLETLDKGEARVAERGADGKWKVNQWLKKAVLLSFRLNDMGVIPGGPGQATWWDKVPSKFEGWGENRFRDAGFRAVPGAVVRRSAFIAKNVVLMPSFVNLGAYVDESTMVDTWATVGSCAQIGKRVHISGGAGIGGVLEPLQAEPVIIEDDCFIGARSEVAEGVIVRKGAVLAMGVFLGASTKIVDRDTGEVFIGEVPEYSVVVPGALPGKPMKNGHIGPSTACAVIVKRVDERTRSKTSINELLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP4_RHOJR
Sequence: MSQYTIPHVIERTPAGERSFDIFSRLLNERIVFLGTEIDDGVANVVMAQLLHLQADSSDQEIGLYINSPGGSTTAMLAIYDTMQFLRPTIATYCMGQAASAAAVLLAAGTKGHRHVLAHSRTLLHQPSTQGNGTISDLALQAAEIMRVRSQTEAILSKHTGQTVERLRRDTDRDRIFTAEEAIEYGLADTLVAA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 4, Endopeptidase Clp 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTG3_RAT
Sequence: MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTQILQEKYKNHWYPEKPSKGQAYRCIRVNKFQRVDPDVLKACEDSCILYSDLGLPKELTLWVDPCEVCCRYGKKNNAFIVASFENEDENKDEISKKVSRALDKVTSDYHSGSSSSDEDTSKEVEVKPSAVATTPSPVYQISELIFPPLPMWHPLPRKKPGMYRGGGHQSHYPPPVPFAYPSPGRKNKAFRPIPVTWVPPPGMHCDRNHWINPHMLAPH
What is the function of this protein?
Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase.
What are the official names of this protein?
Protein BTG3, rBTG3, BTG family member 3.
What is the protein family that this protein belongs to?
Belongs to the BTG family.
Protein: CAPSD_HBVD6
Sequence: MDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGVNLEDPASRDLVVSYVNTNMGLKFRQLLWFHISCLTFGRETVIEYLVAFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: AUP1_HUMAN
Sequence: MELPSGPGPERLFDSHRLPGDCFLLLVLLLYAPVGFCLLVLRLFLGIHVFLVSCALPDSVLRRFVVRTMCAVLGLVARQEDSGLRDHSVRVLISNHVTPFDHNIVNLLTTCSTPLLNSPPSFVCWSRGFMEMNGRGELVESLKRFCASTRLPPTPLLLFPEEEATNGREGLLRFSSWPFSIQDVVQPLTLQVQRPLVSVTVSDASWVSELLWSLFVPFTVYQVRWLRPVHRQLGEANEEFALRVQQLVAKELGQTGTRLTPADKAEHMKRQRHPRLRPQSAQSSFPPSPGPSPDVQLATLAQRVKEVLPHVPLGVIQRDLAKTGCVDLTITNLLEGAVAFMPEDITKGTQSLPTASASKFPSSGPVTPQPTALTFAKSSWARQESLQERKQALYEYARRRFTERRAQEAD
What is the function of this protein?
(Microbial infection) Following Dengue virus infection, required for induction of lipophagy which facilitates production of virus progeny particles.
What are the official names of this protein?
Lipid droplet-regulating VLDL assembly factor AUP1, Ancient ubiquitous protein 1.
What is the protein family that this protein belongs to?
Belongs to the AUP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet. SUBCELLULAR LOCATION: Cytoplasmic vesicle, autophagosome. Note=(Microbial infection) Upon Dengue virus infection, relocates from lipid droplets to autophagosomes.
Protein: IGFR1_BOVIN
Sequence: MGPLRLLPTAVLLLAQAAPWEASQHCGRLEYWNPDNRCCGSCLQRFGPPPCADLEFSENCGLDDAGNHVMHPFQECPPGQCNRNSAELCSLCGGGATAPIPSGSRGGTGRPCREPVPNKEPCPLTPGKSSILSSQEPSSPGIPSVSWTSEHKAPQQAWPSLSFALFLVLVLLVTSAIILLALQRHHRRLDQGKAVQHPYPSLVCSDLDTHTRFLHLSSPASLETSEARDSWKEVSLSPLLGREMPSLESQPLSRLLDELEVLEELILLLDPEPGPGGRMACGTTRHLAARYGLPAAWSTFAYSLRPSRSPLRALIEMVVAREPSASLGQLGTHLAQIGRADALQVLSKLGSSGACLA
What is the function of this protein?
Probable cell membrane receptor for the IGF-like family protein IGFL.
What are the official names of this protein?
IGF-like family receptor 1, Transmembrane protein 149.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS10_BACC0
Sequence: MAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGATVSGPIPLPTEKTVYTILRAVHKYKDSREQFEMRTHKRLIDIVSPTPQTVDSLMRLDLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ZN474_BOVIN
Sequence: MEREEEKRVSTLQQSFHHSKEPTFLINQAVLFGESHSSFLPEIERDNRGEKIKTNPRKNRPGTVILSKQSSRRIMSGSQPRPPVIPSRRPGFRVCYICGREFGSQSLGIHEPQCLEKWRVENSKLPKHLRRPEPSKPPPFSGSGSYSLQAANEAAFQSSQAQLLPCETCGRTFLPDRLLVHQRSCKQKVEGPRAPSLDRSDDLAGLKKVSSGITTRPRTVICYICGREFGTLSLPIHEPKCLEKWKVENDRLPREFRQPLPQKPQPLLTGQPKHAGPRQGQLVSCPNCSQTFAPDRLPVHQRSCKAQPSGPKVQDLTLGSRGGLKESTNPKPQRNMAAPPVTDKPKMIRRPPTIVCYICGREYGTKSIAIHEPQCLKKWHNENNLLPKELRRPEPKKPEVRTITAKGFYDLDALNEAAWTSAQSQLVPCNICGRTFLPDRLIVHQRSCKPKVAK
What are the official names of this protein?
Zinc finger protein 474.
Protein: K0513_HUMAN
Sequence: METPEVPVGSLIDFGPEAPTSSPLEAPPPVLQDGDGSLGDGASESETTESADSENDMGESPSHPSWDQDRRSSSNESFSSNQSTESTQDEETLALRDFMRGYVEKIFSGGEDLDQEEKAKFGEYCSSENGKGREWFARYVSAQRCNSKCVSEATFYRLVQSFAVVLFECHQMDDFGPAKNLMTMCFTYYHIGKPQLLPPESREKPAGSIDSYLKSANSWLAEKKDIAERLLKNTSARTENVKGFFGGLETKLKGPLARRNEEDENKPQEKRPRAVTAYSPEDEKKGEKIYLYTHLKQQPIWHTLRFWNAAFFDAVHCERTKRSPTTRGDAGEEEEKREKWCHMTQEERDDSLRFNENITFGQLGTFTHNMLAFGLNKKLCNDFLKKQAVIGNLDEEQYKLLSDHIEQMATE
What are the official names of this protein?
Uncharacterized protein KIAA0513.
What are the subcellular locations of this protein?
Cytoplasm.