PharMolix/UniProtQA huggingface dataset:
Protein: EDR2_ARATH
Sequence: MSKVVYEGWMVRYGRRKIGRSYIHMRYFVLEPRLLAYYKKKPQDYQVPIKTMLIDGNCRVEDRGLKTHHGHMVYVLSVYNKKEKSHRITMAAFNIQEALMWKEKIESVIDQHQESQVPNGQQYVSFEYKSGMDTGRTASSSDHESQFSAAEDEEDSRRSLMRRTTIGNGPPESVLDWTKEFDAELANQNSDNQAFSRKHWRLLQCQNGLRIFEELLEVDYLPRSCSRAMKAVGVVEATCEEIFELLMSMDGTRYEWDCSFQFGSLVEEVDGHTAVLYHRLLLDWFPMIVWPRDLCYVRYWRRNDDGSYVVLFRSREHENCGPQPGCVRAHLESGGYNISPLKPRNGRPRTQVQHLIQIDLKGWGAGYLPAFQQHCLLQMLNSVAGLREWFSQTDERGVHTRIPVMVNMASSSLSLTKSGKSLHKSAFSLDQTNSVNRNSLLMDEDSDDDDEFQIAESEQEPETSKPETDVKRPEEEPAHNIDLSCFSGNLKRNENENARNCWRISDGNNFKVRGKNFGQEKRKIPAGKHLMDLVAVDWFKDSKRIDHVARRKGCAAQVAAEKGLFSMVVNVQVPGSTHYSMVFYFVMKELVPGSLLQRFVDGDDEFRNSRLKLIPLVPKGSWIVRQSVGSTPCLLGKAVDCNYIRGPTYLEIDVDIGSSTVANGVLGLVIGVITSLVVEMAFLVQANTAEEQPERLIGAVRVSHIELSSAIVPNLESE
What is the function of this protein?
Negative regulator of the salicylic acid- (SA-) mediated resistance to pathogens, including the biotrophic powdery mildew pathogens Golovinomyces cichoracearum and Blumeria graminis, and the downy mildew pathogen Hyaloperonospora parasitica, probably by limiting the initiation of cell death and the establishment of the hypersensitive response (HR).  Prevents ethylene-induced senescence.  Binds to phosphatidylinositol-4-phosphate (PtdIns(4)P) in vitro.
What are the official names of this protein?
Protein ENHANCED DISEASE RESISTANCE 2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. Endosome membrane; Single-pass membrane protein.
Protein: KDSA_CAMJR
Sequence: MKKMILIAGPCVIESKDLIFKVAEQLKNFNENPNIEFYFKSSFDKANRTSINSFRGPGLEEGLKILQSVKDEFGMKILTDIHESNQANPVSEVADVLQIPAFLCRQTDLLVAAAKTKAKINIKKGQFLNPSDIKYSVKKVLQTRGIEDEGYEAAQRNGVFVAERGASFGYGNLVVDMRSLVIMREFAPVIFDATHSVQMPGAAGGSSGGKSEFVEPLARAAAAVGIDGFFFETHINPCEALCDGPNMLNLTRLKNCVNTLLEIQNIIKENK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_CHLL2
Sequence: MNIHEYQGKDILKKFGVSVPRGIVAFSPDEAKQAAQQLFEEQGSPVVVVKAQIHAGGRGKAGGVKLAKSPDEAMEIARQMLGATLVTHQTGPEGKQVSRLLVEEGMNIDREFYVGITLDRSTSRNVLMVSTEGGMEIEKVAEETPDKLLKIQVDPLYGLQGFQAREAAFFLGLEGEQFRNAVTFIIALYNAYMTIDASLAEINPLVVTKEGRVLALDAKINFDGNALFRHKNFLELRDTNEEDPFEVEASKSNLNYVRLDGNVGCMVNGAGLAMATMDMIQLAGGRPANFLDVGGGASPETVEEGFKIILSDKNVRAILVNIFGGIVRCDRVAGGIIQAARKIGLNLPVIVRLEGTNAEIAQKMLDESGLNLIAANGLHDAAAKVNQALAAG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: DPO1_HELPY
Sequence: MEQPVIKEGTLALIDTFAYLFRSYYMSAKNKPLTNDKGFPTGLLTGLVGMVKKFYKDRKNMPFIVFALESQTKTKRAEKLGEYKQNRKDAPKEMLLQIPIALEWLQKMGFVCVEVNGFEADDVIASLATLSPYKTRIYSKDKDFNQLLSDKIALFDGKTEFLAKDCVEKYGILPSQFTDYQGIVGDSSDNYKGVKGIGSKNAKELLQRLGSLEKIYENLDLAKNLLSPKMYRALIHDKASAFLSKELATLERGCIKEFDFLSCAFPSENPLLKIKDELKEYGFISTLRDLENSPTPLILDNAPLLDNTPALDNTPKKSCMIVLESAAPLSAFLEKLEKTNARVFARLVLDKEKKVLALAFLYEDQGYFLPLEEALFSPFSLEFLQNAFFKMLQHAQIIGHDLKPLLSFLKAKYQVPLENIRIQDTQILAFLKNPEKVGFDEVLKEYLKEELIPHEKIKDFKTKAEKLELLSVELNALKRLCEYFEKGGLEENLLSLAREIETPFMKVLMGMEFQGFKIDAPYFKRLEQEFKNELHVLERQILELIGVDFNLNSPKQLSEVLYDKLGLPKNKSHSTDEKSLLKILDKHPSIALILEYRELNKLFNTYTTPLLRLKDKDDKIHTTFIQTGTATGRLSSHSPNLQNIPVRSPKGLLIRKGFIASSKEYCLLGVDYSQIELRLLAHFSQDKDLMEAFLKGRDIHLETSKALFGEYLAKEKRSIAKSINFGLVYGMGSKKLSETLNISLNEAKSYIEAYFKRFPSIKDYLNRMKEEILKTSKAFTLLGRYRVFDFTGANDYVKGNYLREGVNAIFQGSASDLLKLGMLKVSERFKNNPSVRLLLQVHDELIFEIEEKNAPELQQEIQRILNDEVYPLRVPLETSAFIAKRWNELKG
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: DHE4_HELPY
Sequence: MYVEKILQSLQKKYPYQKEFHQAVYEAITSLKPLLDSDKSYEKHAILERLIEPEREIFFRVCWLDDNNQIQVNRGCRVEFNSAIGPYKGGLRFHPSVNESVIKFLGFEQVLKNSLTTLAMGGAKGGSDFDPKGKSEHEIMRFCQAFMNELYRHIGATTDVPAGDIGVGEREIGYLFGQYKKLVNRFEGVLTGKGLTYGGSLCRKEATGYGCVYFAEEMLQERNSSLEGKVCSVSGSGNVAIYTIEKLLQIGAKPVTASDSNGMIYDKDGIDLELLKEIKEVRRGRIKEYALEKKSAEYTPTENYPKGGNAVWHVPCFAAFPSATENELSVLDAKTLLSNGCKCVAEGANMPSSNEAIGLFLQAKISYGIGKAANAGGVSVSGLEMAQNASMHPWSFEVVDAKLHHIMKEIYKNVSQTAKEFKDPTNFVLGANIAGFRKVASAMIAQGV
What is the function of this protein?
Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
What are the official names of this protein?
NADP-specific glutamate dehydrogenase, NADP-GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: YSCT_YERPS
Sequence: MIADLIQRPLLTYTLLLPRFMACFVILPVLSKQLLGGVLLRNGIVCSLALYVYPAVANQPYIEVDAFTLMLLIGKEIILGLLIGFVATIPFWALESAGFIVDNQRGAAMASLLNPGLDSQTSPTGLLLTQTLITIFFSGGAFLSLLSALFHSYVNWPVASFFPAVSEQWVDFFYNQFSQILLIAAVLAAPLLIAMFLAEFGLALISRFAPSLNVFVLAMPIKSAIASLLLVIYCMQMMSHASKAMLLVMDPISLLIPVLEK
What is the function of this protein?
Component of the yop secretion machinery.
What are the official names of this protein?
Yop proteins translocation protein T.
What is the protein family that this protein belongs to?
Belongs to the FliR/MopE/SpaR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL29_MYCAP
Sequence: MLYKDIKVSHLMNSNDELQKLVKDFEAELWTLNFKKSVGSLDQSHKIRAIRRDIARIKTELNAREKGAK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: BL1S5_HUMAN
Sequence: MSGGGTETPVGCEAAPGGGSKKRDSLGTAGSAHLIIKDLGEIHSRLLDHRPVIQGETRYFVKEFEEKRGLREMRVLENLKNMIHETNEHTLPKCRDTMRDSLSQVLQRLQAANDSVCRLQQREQERKKIHSDHLVASEKQHMLQWDNFMKEQPNKRAEVDEEHRKAMERLKEQYAEMEKDLAKFSTF
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes (PubMed:32565547).  In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.  The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension.  Plays a role in intracellular vesicle trafficking.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 5, BLOC-1 subunit 5, Protein Muted homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S5 family.
Protein: RL1_PELUB
Sequence: MPSKRFKQLPEKTKDLTADVIENLLATVKKNCTTKFDESIDLSFQVNNKQKKGEVNIRTVVNLPGGTGKKVKVAVVCEDTKAKEAKDAGADIVGSDEFIDKIKAGELNFEKLICTPGMMVKLSKLGKVLGPKGLMPNPKLGSVSEDIKQAVTNAKSGQAEIRNDKDGNIGVSIGKKSFHDDQLLKNFHAILDTLEKEKGNLTLKGDLIKNTFITSSMGVSYKVKLGKAI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ISY1_EMENI
Sequence: MARNSEKAQSMLFRFRAQQAADLGIIDIGRTRRPKAITSVDSIPACEKWRGQVLKEISRKVSRIQEPSLSDHQIRDLNDEINKLMREKWAWEMQIRNMGGPNYMRGSGRVYDDEGREIPGGGKGYRYFGRARELPGVKEMLEAAARRGRGPAEEEEDDGKTVGRGGDIATKKVDANYFGYGLDEEDGTLLAYEMQREKEAVEKLRKEGEDEEDVEDGWEPLPGDAGDGIEWRLPTLEEVQEELVDRRRRRLLEKIS
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor isy1.
What is the protein family that this protein belongs to?
Belongs to the ISY1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TAT_CATRO
Sequence: MASKMVEIVSKMFIKPSSPTPQSLRRYNLSSIDQTIDSEVTSLAFFYTYNPSHESSKIGDLLKNSLSKTLVSYYQFAGRLIENDYIDCNDEGVEFVEVRIHGRMNDILKRGKSFATDLVLPTRIIALHEDSLLIVQLSHFDCGGIAIGFGASHKVSDGVSNVMFMKDWASSTSLSTFHKPTPLLTADSIFPPEDNKLLSNKSIVSFQQCLGKRFVFSTEAIEKLKSKAIEYGIQKPSRVEVVTAFLCQCAANCDLPRKKPYAIISAVNLRPYLALPQNSIGNIFSFYFCINDEGMDNQFSALISKLRNGKQKLLENIISKEKLTYESQMQELTKCLDQLNISSLDTYFCSSWCRFPVYDIDFGWGKPILVSPFQPHVKDLILLMDSPEGDGIEALITMEEKKMAAFEKNEELRSFAYLDSPEPEALIIPEEDKSFE
What is the function of this protein?
Component of the monoterpenoid indole alkaloids (MIAs, e. g.  echitovenine, tabersonine, lochnericine, 19-hydroxytabersonine and horhammericine) biosynthetic pathway; MIAs are used in cancer treatment and other medical applications (PubMed:31009114).  Acyltransferase catalyzing the conversion of horhammericine to 19-O-acetylhorhammericine, of 19-hydroxytabersonine to 19-O-acetyltabersonine and of minovincinine to echitovenine (PubMed:29438577, PubMed:31009114).
What are the official names of this protein?
Tabersonine-19-hydroxy-O-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AROA_BRADU
Sequence: MPVTGRGPCGTCAPALRSTSKDTILTHSDQPRPLQSRANGPLTGKVRVPGDKSISHRALILGALAVGETRISGLLEGEDVLNTAKSMQALGASVERTGDFAWKVQGVGVAGFAQPKAALDFGNSGTGCRLVMGAVAGCPISAVFDGDASLRSRPMRRILDPLEKMGARVVSGGEGGRLPLTLQGARDPLPITYKTPVASAQIKSAVLLAGLAAPGTTTVIESEASRDHTELMLKHFGADITSTKEGQHGRRITLVGQPELHGANVVVPADPSSAAFPVVAALIAEGSDVVLSDVMTNPLRTGLFTTLREMGASIEESEVRGDAGEPMAQLRVRASKLRGVEVPPERAPSMIDEYLVLAVAASFAEGTTIMRGLQELRVKESDRLEATAEMLRVNGVKVEVSGDDLVVQGRGHVPGGGTVATHMDHRIAMSALVMGCASDQPVTVDDTAFIATSFPDFIPMMRSLGAEFS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP19_DROME
Sequence: MATAVPMKKNWSPSMKHNDMERWICIYPAYINRKKTRQEGRRLPKENCVDNPSYIEIRDVLSVSNLQFLMENKKYCRENSSEMEFRGRVRVQLRNVDGTLYNNDFPTRESIMLHIASKIPQLKTRQNKSGDSYHQQSQPQSNASGSGGGGGGKKGKGKRR
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  Binds directly to 7SL RNA (By similarity).  Mediates binding of Srp54 to the SRP complex (By similarity).
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: Y3115_MYCBO
Sequence: MTRINPIDLSFLLLERANRPNHMAAYTIFEKPKGQKSSFGPRLFDAYRHSQAAKPFNHKLKWLGTDVAAWETVEPDMGYHIRHLALPAPGSMQQFHETVSFLNTGLLDRGHPMWECYIIDGIERGRIAILLKVHHALIDGEGGLRAMRNFLSDSPDDTTLAGPWMSAQGADRPRRTPATVSRRAQLQGQLQGMIKGLTKLPSGLFGVSADAADLGAQALSLKARKASLPFTARRTLFNNTAKSAARAYGNVELPLADVKALAKATGTSVNDVVMTVIDDALHHYLAEHQASTDRPLVAFMPMSLREKSGEGGGNRVSAELVPMGAPKASPVERLKEINAATTRAKDKGRGMQTTSRQAYALLLLGSLTVADALPLLGKLPSANVVISNMKGPTEQLYLAGAPLVAFSGLPIVPPGAGLNVTFASINTALCIAIGAAPEAVHEPSRLAELMQRAFTELQTEAGTTSPTTSKSRTP
What are the official names of this protein?
Putative diacyglycerol O-acyltransferase Mb3115, Putative triacylglycerol synthase Mb3115.
What is the protein family that this protein belongs to?
Belongs to the long-chain O-acyltransferase family.
Protein: PLSY_WOLSU
Sequence: MSFISNPNIHFYLLAYFIGGIPFGYLLSRFFYNINLQEVGSGSIGATNVLRALKERDPKKAKMMAALTMLLDALKGALVILVAKMAGMSVETQWAIAVLAVVGHCFSPYLKLEGGKGVATGLGVMAVMLPLEAAIGLVVWLVVGKTLKISSLSSLLGLGALLISSFLIHPEIPEIGTHAPLLIIAFVIFYKHIPNLVRLFQGKEGRVV
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MYO1_BOTFB
Sequence: MGISRRPKGNNNASAAESAPSGKPNIQKAQFDTTKKKEVGVSDLTLISKVSNEAINENLKKRFDNREIYTYIGHVLVSVNPFRDLGIYTDAVLDSYKGKNRLEMPPHVFAVAESAYYNMNGYKDNQCVIISGESGAGKTEAAKRIMQYIANVSGGSNSSIQEIKDMVLATNPLLESFGNAKTLRNNNSSRFGKYLQLQFNAQGEPVGADITNYLLEKTRVVTQIKDERNFHIFYQFTKGASQAYRENFGIQQPSQYLYTSKAGCFDVDGIDDLAEYQDTLNAMKIIGLSQAEQDEIFRMLAAILWTGNIQFREDEDGYAAVVDQSVVDFLAYLLDCDAGHVIQAITIRILTPRNGEVIESPANVPQALATRDALAKAIYNNLFDWIVERVNKSLTARSATSNSIGILDIYGFEIFEKNSFEQLCINYVNEKLQQIFIQLTLKTEQEEYAREQIQWTPIKYFDNKIVCDLIESMRPPGIFSAMKDATKTAHADPAACDRTFMQAISGMSNPHLTPRQGNFIVKHYAGDVSYTVEGITDKNKDQLLKGLLNLFGQSKNQFIHELFPHQVDQDNRKQPPSAGDKIKASANDLVATLMKATPSYIRTIKPNENKSPTEYNEKNVLHQVKYLGLQENVRIRRAGFAYRQTFDKFVERFYLLSPKTSYAGDYIWTGDSKTGAMQILKDTNIPVEEYQMGVTKAFIKAPETLFALEHMRDRYWHNMAARIQRVWRAFLQIRIEAATRIQRMFRKKREGKEFLELREKGHQVLQGRKERRRYSLLGSRRFMGDYLGIAATTGPGSKIRGSINLPANEATIFSCRGEILETKFGRSSKLSPRIFIMTKAKFYIVSQQLVNKQVQIAVEKAIPLGAIKFVSISTCRDDWFSLGVGSPQEADPLLTCVFKTELFTHMQGAMPGGGFNLKIGDSIEYAKKPNKMQLIKVVKDSQQAQDHYKSATIHTQAGEPPTSRSKPLPKGKPVAPKPFTSGRLIKPGGPGGRPSKLTNGNRPTPKPVPSPAAARPVPTPAAAAMPIPAPIPAANPIAASIPVHTRNPSLQSAQSTRAVPPPPPPAPPAPPPAPASKEPQYRVLYEFAGQSANEFSLKQGEIETVLQKRQWKWHRHPPPPIASRLTPPPPPGPPKMNGANGAAVRSKHTPPAPPAKRPVAGRKPAPPPAPRDSGMSISSNGSGNNSGRSTPTPSLAGGLAEALRARQSAMQGNAKKEDEDDW
What is the function of this protein?
Type-I myosin implicated in the organization of the actin cytoskeleton.  Required for proper actin cytoskeleton polarization.  At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly.  Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity).
What are the official names of this protein?
Myosin-1, Class I unconventional myosin, Type I myosin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch.
Protein: RL13_STAA3
Sequence: MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL16_PROA2
Sequence: MLMPKRVKHRKVMRGKMKGNAGRGTTVTFGTYALKALEPAWITSRQIEAARVAMNRFMKRDGKIWIRIFPDKPVTKKPAETRMGSGKGNPEFWVAVVKPGRIMFEAEGVSQEVATEAFRLAAKKLPIKTKFIVRPEHEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SG11B_HUMAN
Sequence: MRQRLLPSVTSLLLVALLFPGSSQARHVNHSATEALGELRERAPGQGTNGFQLLRHAVKRDLLPPRTPPYQVHISHREARGPSFRICVDFLGPRWARGCSTGN
What is the function of this protein?
Has antimicrobial activity against E. coli (By similarity).  Plays a role in the defense response in the male reproductive tract, contributing to sperm maturation, storage and protection (By similarity).
What are the official names of this protein?
Sperm-associated antigen 11B, Human epididymis-specific protein 2, He2, Protein EP2, Sperm antigen HE2.
What is the protein family that this protein belongs to?
Belongs to the SPAG11 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DTD_ASHGO
Sequence: MRVVIQRVSQASVVVENKLISSIKTGYMLLVGISTEDTIADIEKSVRKVSGLRLFPDDSNAQWKRSIKDIGGEVLSISQFTLIARTKKGTRPDFHEAQKGHLALEMYDRFLDLLRQELGEKQVQDGEFGAMMSCSLTNEGPVTIIYDTKE
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_YERPY
Sequence: MGKNVVVLGTQWGDEGKGKVVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVISIIGNGVVLAPDALMKEMTELEARGVPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVSDLFNKETFAIKLKEIVEYHNFQLVHYYKEAAVDYQKVLDDVLAIADILTAMVVDVSELLDNARKQGELIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGIVKAYSTRVGAGPFPTELNDETGEFLRKQGNEYGATTGRSRRTGWLDIVAVRRAVQINSLSGFCMTKLDVLDGLKEVKLCVGYRMPDGREVDTTPLAAEGWEGIEPIYETMPGWSETTFGVKEHSKLPQAALNYIQRVEELTGVPIDIISTGPDRDETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_ROSDO
Sequence: MQVILLERVAKLGQMGEVVDVKPGYARNFLLPQGKALSASKANIEAFEQQKAQLEARNLETRKEAEALAAKLDGQQFIVIRSASDSGALYGSVTTRDAAEAATEAGFTVDRKQVVLSPIKELGLHAVQVVLHPEVDATIHLNVARSVEEAELQASGKSIQELAAEEEAAAEFEIQELFDDIGAAASEDEELAETAGVAPAEPSEEDDSAKA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: COBQ_PSEE4
Sequence: MTTLMVQGTTSDAGKSTLVTALCRWLLRQGVAVVPFKPQNMALNSAVTADGGEIGRAQAVQAQACRLAPHTDMNPVLLKPNSDTGAQVIVHGRAVTSMNAVAYHDYKVIAMQAVLASHERLRQAYPVVMVEGAGSPAEINLRAGDIANMGFAEAVDCPVILIADINRGGVFAHLVGTLELLSPSEQARVKGFVINRFRGDIALLQPGLDWLEQRTGKPVLGVLPYVTDLHLEAEDAIDVRQAVKGERVLKVIVPVLPRISNHTDFDPLRLHPQVDLQFIGPGQPIPPADLIILPGSKSVRADLSQLRERGWDSAIARHLRYGGKLIGICGGLQMLGHEVHDPLGLEGAAGSSAGLGLLDYSTVLEAEKQLRNVAGTLGLEQAPVSGYEIHAGVTHGPGLEHPAVQLDDGRNDGAISADGQILATYLHGLFEGSQSCAALLRWAGLADAQAIDYEALRERDIERLADLVEQHLDTERLRQLCGVTADA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: SYS_CAMFF
Sequence: MINLKLIETNFDEFNAKLKAKKVDEGVLKNLLDTYNELKIKKQELENLQAVQNAKSKEVGILARSGADTTLLKTELEENKKLMQTASNLVSELETKLDTVASRVPNVIDDDVPLGKDDNDNVCIKTILEPREFNFTPKEHFELGENLGWLDFATGAKLSGSRFTVLRSDGARLSRALVNFMIDFNTARGFELVNVPFLVNSNTLYGTGQLPKFEEDLYKIRDEDLYLIPTSEVPVTNIYNNEIIPVENLPIKMTCYSACFRQEAGSAGRDTRGMIRQHQFEKVELVSISKPEDSAKILDEMVSCASDMLKELGLPHRHMMLCSADLGFGAAKTIDLEVWLPGQGKYREISSISNTRDFQARRAKIRYKDGKKNALVHTLNGSSLAVGRTLIAIMENYQNSDGSINIPEVLKKYM
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YZ31_AQUAE
Sequence: MSTGNIEAGVYYESDGSDEHIKKLREYFEKIKEEYSESFGDDLLGFTVNPVKPQSFEFILVGNDDIGLHSYVEVKLQEGIVLGKITSIFAYDMGFFANPFTSQESSVFAPVEDFKTIFSKGKDDEWKKAAIYAYLNNNGNKLKIATADVIGILKDGKLDILRNPFHVGEPVYKISEKTLGKILKKNFSGRDMEVPVKVGVIENSDIDVFVDANEVISKHMLVLGTTGSGKSYFTKRFISSLLESDKEVEVYVLDPHGEYFNDLKSYIDEN
What are the official names of this protein?
Uncharacterized protein aq_aa31.
Protein: CLIC4_PONAB
Sequence: MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVSTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRLTK
What is the function of this protein?
Can insert into membranes and form poorly selective ion channels that may also transport chloride ions.  Channel activity depends on the pH.  Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions.  Promotes cell-surface expression of HRH3.  May play a role in angiogenesis (By similarity).
What are the official names of this protein?
Chloride intracellular channel protein 4.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle membrane; Single-pass membrane protein. Nucleus. Cell membrane; Single-pass membrane protein. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain. Present in an intracellular vesicular compartment that likely represent trans-Golgi network vesicles (By similarity).