PharMolix/UniProtQA huggingface dataset:
Protein: SYE_XANCB
Sequence: MTCRTRFAPSPTGYLHIGGARTALYCWLEARHRGGQFVLRIEDTDRERSTQAAIDAILEAMEWLGLGYDEGPIYQTQRIARYQEVAEQLLAQGKAYYAYETREELDAMREAAMAKQEKPRYNGAAREQQLPYRDDPNRVIRFKNPLAGTVVFDDLIKGRIEIANSELDDMVIFRPDGYPTYNFAVVVDDWDMGITEVIRGDDHINNTPRQINIYEALGAPVPKFAHMPMILDEQGAKLSKRTGAADVMQYKDAGYLPHALINYLARLGWSHGDQELFSQQELLDLFDVKDVNSKAARLDMAKLGWVNQHYLKTDDPASIAPQLEYQLRKLGIDVAAGPAAADVVVALRERVQTLKEMAEKAVVWYQPLETYDEAAVIKHLKLGAEVPLGKAREMLAALNEWSVENVSAALHAAAAALELGMGKVAQPLRVAITGTQVSPDISQTVYLAGREGALKRIDAALIKIGAA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHE3_THEKO
Sequence: MVEIDPFEMAVQQLERAAQFMDISEEALEWLKRPMRIVEVSVPVEMDDGSVKVFTGFRVQHNWARGPTKGGIRWHPAETLSTVKALATWMTWKVAVVDLPYGGGKGGIIVDPKKLSEREQERLARSYIRAVYDVIGPWTDIPAPDVYTNPKIMAWMMDEYETIMRRKGPAFGVITGKPPGVGGIVARMDATARGAAFTIREAAKALGWDDLKGKTIAIQGYGNAGYYLHKIMSEEFGMKVVAVSDSKGGIYNPDGLPPADEVLKWKKEHGSVKDMPGTQNITNEELLELEVDILAPSAIEGVITKENADNVKAKIVAEVANGPVTPEADEILHEKGILQIPDFLCNAGGVTVSYFEWVQNINGFYWTVEETRKRLDDKMTKAFWDVFNTHKEKNIHMRDAAYVVAVSRVYEAMKHRGWVKK
What are the official names of this protein?
Glutamate dehydrogenase, GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_CHLT2
Sequence: MQTSRISSFFRGLVHLYRWAISPFLGAPCRFFPTCSEYALVALKKHPLRKSLFLIAKRLLKCGPWCIGGIDLVPRTSVEEYLSSPTPLAESPDDRTVPHTQETS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: END4_STAA8
Sequence: MLLGSHVSMSGKKMLEGSAIEAHEYGETTFMIYTGAPQNTRRKSIEDLNITKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKGTEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQQFDPELKNKVMQQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: PHOSP_MMVR
Sequence: MNRYSRRSRHPNPPVPNQEEPERDPNHIDQDLADLAQPLVLKERHAVMAPTQPSLSDVINEERQAPITFGNPPEVMANARLSALGYDNLTEREKRILAVGVRCGEAAKDYHSLTTTKKWIEDELKSQMVALASSTRTLTEAASLHTTFAMLHSPSIKRKAEAMSHISQGEESIDISKLNKTGMEDIWVAMESESKEDAVDTYLRNILEVDPTQFYAIDGWGLYLDFIPTWHYIAAGKNSAQFKTSYADEIVEQRAAFERVLSKRPRVEI
What is the function of this protein?
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication.  Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the nucleorhabdovirus protein P family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: Y1338_STRS2
Sequence: MRRSFYSWLMTQRNPKSNEPVAILADYAFDESDFPKQSDNFDEVSRFLEESASFAFSMSDFDAIWEDYLGH
What are the official names of this protein?
UPF0346 protein SSU98_1338.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: MYPOP_HUMAN
Sequence: MASAAAGEAEETTRLRKPRFSFEENQILIREVRAHYPQLYGAQSRRVSVAERRRVWDGIAAKINGITSWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAGPAAEDAFSAEEETIFAILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARPSCTPQEGGCPRPKERESPPPSALQPVQLPRLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPHDSPPHKRRKGFPTRKRRGRWKSP
What is the function of this protein?
Transcriptional repressor; DNA-binding protein that specifically recognizes the core sequence 5'-YAAC[GT]G-3'.  Dimerization with PFN1 reduces its DNA-binding capacity (By similarity).
What are the official names of this protein?
Myb-related transcription factor, partner of profilin, Myb-related protein p42POP, Partner of profilin.
What are the subcellular locations of this protein?
Nucleus.
Protein: YHBW_ECOLI
Sequence: MTDKTIAFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRYWLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLYPGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPGYGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKPYAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGVQQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELAMDVKEELLG
What are the official names of this protein?
Luciferase-like monooxygenase.
What is the protein family that this protein belongs to?
To bacterial alkanal monooxygenase alpha and beta chains.
Protein: CPXS_PORPU
Sequence: MEQLISFFDRSKGKWISQRTTYKLSNKQMNSLQSSIIIKPDQSSSNSQLIASLRWGEISRQIIKNLNNQDFVNGNFKFHLRFTNQFNTKQVVTLCSITDKSLITFKTRYGSTTVDETYWFATDNLRLSTSIIKQCNFCVAVSFCSEIKI
What is the function of this protein?
Might function to covalently attach a chromophore to Cys residue(s) of phycobiliproteins.
What are the official names of this protein?
Chromophore lyase CpcS/CpeS homolog, ORF149.
What is the protein family that this protein belongs to?
Belongs to the CpcS/CpeS biliprotein lyase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LAC_SANBA
Sequence: AIGPVDEV
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.  Exhibits broad substrate specificity against a range of aromatic compounds with highest activity against guaiacol.  Shows lower activity against 4-methylcatechol, 4-hydroxyindole, catechol, hydroquinone and 2,6-dimethoxy-phenol.
What are the official names of this protein?
Laccase.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RABP2_RAT
Sequence: MPNFSGNWKIIRSENFEEMLKALGVNMMMRKIAVAAASKPAVEIKQENDDTFYIKTSTTVRTTEINFKIGEEFEEQTVDGRPCKSLVKWESENKMVCEQRLLKGEGPKTSWSRELTNDGELILTMTADDVVCTRVYVRE
What is the function of this protein?
Transports retinoic acid to the nucleus.  Regulates the access of retinoic acid to the nuclear retinoic acid receptors (By similarity).
What are the official names of this protein?
Cellular retinoic acid-binding protein 2, Cellular retinoic acid-binding protein II, CRABP-II.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Nucleus. Note=Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.
Protein: CH60_COXB2
Sequence: MAAKVLKFSHEVLHAMSRGVEVLANAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELEDKFENMGAQMVKEVASRTSDDAGDGTTTATVLAQAILVEGIKAVIAGMNPMDLKRGIDKAVTAAVAELKKISKPCKDQKAIAQVGTISANSDKSIGDIIAEAMEKVGKEGVITVEDGSGLENALEVVEGMQFDRGYLSPYFINNQQNMSAELENPFILLVDKKISNIRELIPLLENVAKSGRPLLVIAEDIEGEALATLVVNNIRGVVKVAAVKAPGFGDRRKAMLQDIAVLTGGKVISEEVGLSLEAASLDDLGSAKRVVVTKDDTTIIDGSGDAGDIKNRVEQIRKEIENSSSDYDKEKLQERLAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALIRVLKSLDSVEVENEDQRVGVEIARRAMAYPLSQIVKNTGVQAAVVADKVLNHKDVNYGYNAATGEYGDMIEMGILDPTKVTRTALQNAASIAGLMITTECMVTEAPKKKEESMPGGGDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_BACAH
Sequence: MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMNLSWVPVHKSWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDPRYKELKKGEFPLTECLVDTEKRVLNYWHSEIAPSLKSGEKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDDDLRPIRHYYLSMDGEVPEGEFPKHIVF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ULAB_SALCH
Sequence: MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEYKSELSGADIIIASTHIAGEISVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIB component, Ascorbate-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_STRPJ
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEGNEETTEVVVDTAVETVEETVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RPOC2_CRUWA
Sequence: MAERANLVFHNKVIDGTAIKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSWILEKHHHYGNVHAVEKLRQSIEIWYATSEYLRQEMNPNFRMTDPFNPVHMMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTIRGISVSPRNKNRMMSERIFIQTLIGRVLADDIYIGSRCVAFRNQDLGIGLVNGLITSGTQSISIRTPFTCRSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPYNGKIKFNEDLVHPTRTRHGHPAFLCYIDLSVIIESEDIIHSVTIPPKSFILVQNDQYVESEQVIAEIREGTYTFHFKERVRKYIYSDSEGEMHWSTDVSHAPEFTYSNVHLLPKTSHLWILSGSSCGSSLILFSIHKDQDQMNIPFLSVERKSISSLSVNNDQVSQKFLSSDFADQKKSGIPDYSELNGNLGTSHYNFIYSAIFHKNSDLLAKRRRNRFLIPFQSIQEQEKEFIPHSGISIEIPINGIFRRNSIFAFFDDPRYRRKSSGILKYGTLKADSIIQKEDMIEYRGVQKFKTKYEMKVDRFFFIPEEVHILPESSDIMVQNYSIIGVNTRLTLNIRSQVGGLIRVERKKKRIELKIFSGDIHFPDKTDKISRHSGILLPPGKGKTNSKESKKFKNWIYVQRITPTKKKFFVLVRPVATYEIADSINLATLFPQDLFREKDNIQLRVFNYILYGNGKPTRGISHTSIQLVRTCLVLNWDQDNKNSSLEEVRAFFVEVSTKGLIRDFIRIGLVKSHISYIRKRNNSPDSGLISADHMNPFYSISPKAGILQQSLRQNHGTIRMFLNRNKESQSLLILSSSNCFRMGPFNHVKYHNVINESIKKNPLITIKNSSGPLGTAAQISNFYSFLPLLTYNKISVIKYLQLDNLKDIFQVINSYLIDENGRIFNLDPYSNVVLNPFKLNWYFLHKNYHHNYCEETSTIISLGQFFCENLCIAKKEPQLKSGQVLIVQRDSVVIRAAKPYLATPGAKVHGHYREILYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISLNLEKRIKGWNKCITRILGIPWGFLIGAELTIVQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEEGMSNVFLPGELIGLLRAERTGRALEEAICYRAVLLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGVIPAGTGFNKGLVHCSRQHTNILLEKKTKNFSLFEGDMRDILFYHREFCDSSISKSDFSRI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1045_STAES
Sequence: MPIINVKLLEGRSDEQLKDLVTEVTHAVEKTTGANKEAIHVVIEEMRKDHYAVGGVRKSDQ
What are the official names of this protein?
Probable tautomerase SE_1045.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: GCSPA_COXB1
Sequence: MPFIPHTPDDIEKMLAVIGAESIDQLFDEIPSALANIQQVPPGLNEAGITRLMEKREPNKQLCFIGAGAYEHHIPAAVWEIATRGEFYTAYTPYQAEASQGSLQLIYEYQTMMAELMAMDVSNASLYDGASALAEAALMAVRIKRGKAQRILVPASVNPFYRKVLSSIVEQQKINVEIIPFDPTMGIVNSELLKAKNAEGAAAIIIPQPNFFGCLEAVDVLTDWAHANDLLVIASVNPTAMALLKPPGQWGQKGADIVCGEGQPLGVPLASGGPYFGFMCCKKDYVRQLPGRIVGRTVDKKGREGFTLTLQAREQHIRRSKATSNICTNQGLAVVAATIYLSLLGATGLREVALASHTQSRDLFQRLSAVKGVSPVFSSPIFHEFVVRLEKPVEEVLAAMAEQGIQAGFSLKNDYPKLGNGLLICVTDTKTDDDLMAYENALRSIQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: RL9_MYCTA
Sequence: MKLILTADVDHLGSIGDTVEVKDGYGRNFLLPRGLAIVASRGAQKQADEIRRARETKSVRDLEHANEIKAAIEALGPIALPVKTSADSGKLFGSVTAADVVAAIKKAGGPNLDKRIVRLPKTHIKAVGTHFVSVHLHPEIDVEVSLDVVAQS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: BUD25_YEAST
Sequence: MFCTWDSWDTGTSRKSHSPHRNCLAVRFLQLPFSSFLPCVITYMKSWQTSIGDSEFPLTSFQILVTDAEVVVQRIFDCINGYLPGWHYRNTVFIEHTTSYHRSHFCIFVEGVWVCGEFVKKWFEIPFDNRIENYTKQFPWILIGFGNQVSKAL
What is the function of this protein?
Involved in bud site selection.  Required for resistance to the DNA-damaging agent methyl methanesulfonate (MMS).
What are the official names of this protein?
Bud site selection protein 25.
Protein: PURK_STAAS
Sequence: MSFNKLKFGATIGIIGGGQLGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDDEKALNQLGQKCDVITYEFENISAQQLKLLCEKYNIPQGYQAIQLLQDRLTEKETLKSAGTKVVPFISVKESTDIDKAIETLGYPFIVKTRFGGYDGKGQVLINNEKDLQEGFKLIETSECVAEKYLNIKKEVSLTVTRGNNNQITFFPLQENEHRNQILFKTIVPARIDKTAEAKEQVNKIIQSIHFIGTFTVEFFIDSNNQLYVNEIAPRPHNSGHYSIEACDYSQFDTHILAVTGQSLPNSIELLKPAVMMNLLGKDLDLLENEFNEHPEWHLHIYGKSERKDSRKMGHMTVLTNDVNQTEQDMYAKFEGSN
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide synthase, N5-CAIR synthase, 5-(carboxyamino)imidazole ribonucleotide synthetase.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: FAN1_ARATH
Sequence: MLTGRESLLRLIGKRRRFLPNRHLLLSAHTPNSLNLEFNDYGNLVSLAGDDCRLSEDPTSSDDPSKFSDDLSLSTRKKRRLTQTTLLQSSFLSVPKQLEDGLVICTQQKSILDSETFEFSLVQRSEPSESICCKVEDGSCSPSREESLKTVTLDEDNGEAIETFIVGRKFSDVQDLEIGGDIFLLRHPENVKDRNAIKVISGDSEMLGYLPKDISQCLSPLIDDYDLKFEGTITSVPKKSSEAVLIKVVCHKMRSDGWKECELYGDFKPLWEKVLQVVEHQMQFPPKTTRYQLNFNVLLQEVLRSCSHLFTADEKAFLESFPTLSEDSQRLFIRLYTRKGPWFRLSNISYPEVTDSLQALKDLTVRGFMSSVKDANELDNQKMKEITELLNVTELRDILSMNKVFSRTSRKRDLINSLCSCYNDGTRINLATVILERTGLCAKVSSTAESLIWRVERLFFLNGEQDLSSFVLLDLGIIKYPTYKCIDSEQIFSNRTKLLAYEEAIEVAQLMDESLDNEDPQTVLKCIIIAETRISSSSLDSAHAAAFNRFTAPWVNSKVVLLGVSFFENQKRYNRAVYLLRRLLSCFNCDGRRGYWTVRLSTDLEHMGRPNESLTVAEQGLLDPWVRAGSRVALQRRILRLAKPPRRWKTPTFSNLVDNKIPEVTIQGRSLNCEVGIKNRFYGEDGEQCGVEQLALQYYSGEGGGWQGIHTESSIWLTIFGLLMWDILFSDVPGVFQTRFQTAPLDLETESFYLTRKETIESQLEKVANGMAEEILIISYETQRGTACRGVAWERFSLEELRAAVACVGGMCIASLCRHLAQDYRSWCSGMPDLLVWRFKENGYEGEAKLVEVKSEKDRLSEQQRAWLLLLMDSGFNVEICKVRPASLIKT
What is the function of this protein?
Nuclease required for the repair of DNA interstrand cross-links (ICLs) (PubMed:25779053).  Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions (By similarity).  May act upstream of the helicase RECQL4A and the ATPase RAD5A, which is involved in error-free post-replicative repair.  Functions independently of MUS81 pathway, but in a similar pathway with RECQ4A, RAD5A and MFH1 in ICL repair (PubMed:25779053).
What are the official names of this protein?
Fanconi-associated nuclease 1 homolog, AtFAN1.
What is the protein family that this protein belongs to?
Belongs to the FAN1 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to stalled replication forks via its UBZ-type zinc finger.
Protein: Y667_RHOP2
Sequence: MADFLGMMKQAAQLQSKMKAMQAELDQIEVEGLSGGGLVKIRMSAKMEVRGVSIDPSLLKADEGEVLEDLLVAALADAHRKAEAAMQEKMQALTGGLGLPPGLGLG
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein RPB_0667.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MINE_CLOP1
Sequence: MSFLNVFSSRPTPKQVAKDRLKVILIHDRGELSDEVLDKIRLEILDVLSKYVEIENEDVDITVTKSNPIEGESPSLVANIPIKNIKGKAR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: FPG_MYCGE
Sequence: MPELPEVTTVINELKETVLNKPLDQVQVNLRKVLKNIDPQLLNKQLKNQFFTDIKRKGKYIIFLLSNGLYLVSHLRMEGKYFFEERGSKFNQKHVLVEFHFDDGSQLNYHDTRQFGTFHLYEKLEQAAQLNKLAFDPLEAGFDYRKIFQKAQNSKRKVKTFILDQTVISGIGNIYADEILFASKINPETMVDQLTIKEIEILCKNATKILAKAIVMKGTTISSFSFKKDHTGGYQNFLKVHTKKDQPCSVCNQLIVKKKINGRGSYFCLNCQKITTKVSTKLNP
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RLA1_CHICK
Sequence: MASVSELACIYSALILHDDEVTVTEDKINALIKAAGVNVEPFWPGLFAKALANIDIGSLICNVGAGGGAPAAAAPAGGAAPAGGGAAPAEEKKEEEKKEESEESDDDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: STA5A_RAT
Sequence: MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRGQATQLLEGLVQELQKKAEHQVGEDGFVLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNCSSPAGVLVDAMSQKHLQINQTFEELRLITQDTESELKKLQQTQEYFIIQYQESLRIQAQFGQLAQLNPQERMSRETALQQKQVSLETWLQREAQTLQQYRVELVEKHQKTLQLLRKQQTIILDDELIQWKRGQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNRRSNHLEDYNSMSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPDRNLWNLKPFTTRDFSIRSLADRLGDLNYLIYVFPDRPKDEVFAKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGANATYMDQAPSPVVCPQAHYNMYPPNPDPVLDQDGEFDLDETMDVARHVEELLRRPMDSLDPRLSPPAGLFTSARSSLS
What is the function of this protein?
Carries out a dual function: signal transduction and activation of transcription.  Mediates cellular responses to the cytokine KITLG/SCF and other growth factors.  May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.  Binds to the GAS element and activates PRL-induced transcription.  Regulates the expression of milk proteins during lactation.
What are the official names of this protein?
Signal transducer and activator of transcription 5A, Mammary gland factor.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mostly cytoplasmic during pregnancy, whereas it becomes predominantly nuclear during early lactation. It is translocated into the nucleus in response to phosphorylation (By similarity).
Protein: NUDI_ECOSM
Sequence: MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSANREVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.