PharMolix/UniProtQA huggingface dataset:
Protein: RPOZ_EHRRG
Sequence: MARLTVEECMGRTNNKFKLVILASQRAHDLNSGASPVVKHKNSKNTIVALTEIANEQLDVHLLFNLAVQRCRKYMEKFINSDDSYVVHKSKDNIDIFQKNATSNFDELGANSLNVENSKFLDGDNFFLTQKE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: TM100_MOUSE
Sequence: MTEESTKENLGAPKSPTPVTMEKNPKREVVVTTGPLVSEVQLMAATGGAELSCYRCIIPFAVVVFITGIVVTAVAYSFNSHGSIISIFGLVLLSSGLFLLASSALCWKVRQRNKKVKRRESQTALVVNQRCLFA
What is the function of this protein?
Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10 (PubMed:22783020).  Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons (PubMed:25640077).  Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex (PubMed:25640077).
What are the official names of this protein?
Transmembrane protein 100.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Perikaryon. Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Colocalized with HSPA5 in the endoplasmic reticulum (ER). Enriched in ER microsome. Colocalized with BMP4 in neural cell bodies and neural fibers of the enteric nervous system (By similarity).
Protein: G6PI_DESOH
Sequence: MRTSRLTDLDLWKQLKAHAEKMALPENHLKHLTMAPERLAEFSIQALDMVYDFSRQRVDRQAIDLLMELAWERKVTQRFQAMTTGAVVNTTENRAALHTACRDFSKAKRVVNKIDVTAEMARVRKEIREFSEAVHAGQITGATGKPFAHVVVVGIGGSYLGTEFVARALAAYADKGICLHFLANVDIHNFGEIAEAIDPETTLWVIVSKSFTTAETMANANQAAAFMKEQGLDPARHFVSVTSKGSPGDQTGQDAPFPVLRSFHMFDFIGGRYSVTSAVGGVPLSLYLGYDRFETFLKGAHQMDVHAATAPPTTNMPLTAALLGIWNNNFLEYPAQAIIPYASPLARLAPHVQQLYMESNGKSVTAEGKPLGVRSGVIIFGEPGTNAQHSFFQLAHQGAPFPIDFIGVIKPQYDAFQALSRGVTNHQELWANLISQPRALAEGKESEDGHRSFSGNRPSSTILLEDLSPASVGKLLAFYEARTVYEAFVWGINPFDQYGVELGKKLASEIRSQMAAKNRDAGHTFENVDSISRFYLEKLMGKGNDE
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2199_CROS5
Sequence: MISIDLALKYTPLPISVQRKEVEDAQTLYNQIVNAMKSGTSQLIELTCEKQTEKKVAVMSDQISAVILSQKDGGAAAGRVPGFFSMVESEQ
What are the official names of this protein?
UPF0367 protein cce_2199.
What is the protein family that this protein belongs to?
Belongs to the UPF0367 family.
Protein: PSBZ_SACOF
Sequence: MTIAFQLAVFALIATSSVLVISVPLVFASPDGWSNNKNVVFSGTSLWIGLVFLVAILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: WBBD_ECOLX
Sequence: MSDDTPKFSVLMAIYIKDSPLFLSEALQSIYKNTVAPDEVIIIRDGKVTSELNSVIDSWRRYLNIKDFTLEKNMGLGAALNFGLNQCMHDLVIRADSDDINRTNRFECILDFMTKNGDVHILSSWVEEFEFNPGDKGIIKKVPSRNSILKYSKNRSPFNHPAVAFKKCEIMRVGGYGNEYLYEDYALWLKSLANGCNGDNIQQVLVDMRFSKETAKRRGGIKYAISEIKAQYHFYRANYISYQDFIINIITRIFVRLLPTSFRGYIYKKVIRRFL
What is the function of this protein?
Catalyzes the addition of Gal, the second sugar moiety of the O7-antigen repeating unit, to GlcNAc-pyrophosphate-undecaprenol.
What are the official names of this protein?
UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MURD_CUPMC
Sequence: MFGVLQKPHVLVLGLGESGLAMARWCGLNGCRVRVADTREAPANLVFLQAELTTAQFMGGQFTENLLDDIGLVAISPGLSPLEPNTRALLEAAQARSIPVWGEIELFAQAIGYLEATSGYAPRVLAITGTNGKTTTTALTGRLIERAGKTVGVAGNISPSALDKLSACIASATLPDVWVLELSSFQLEYTFSLAPHAATVLNVTQDHLDWHGSMEAYAAAKARIFGPAEKGCLQVLNRQDPLTMNMARRGTTLVTFGTDLPETPGSYGVLREGGMPWLVLAEPDTEADAEQKPRRRKKDDVAADAVVPVRHKRLMPADALHIRGMHNATNAMAALALCRAIDLPLNALLHGLREYRGEPHRVEWVATIDEVEYFDDSKGTNVGATVAALSGLDKHVVLIAGGEGKGQDFSPLVAPVAQYARAVVLIGKDAGALREALGATGKPLIDAGSLEEAVEKSASLAEAGDVVLLSPACASLDMFRNYVHRAQVFRGAVEELALSRGIMP
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_BORBZ
Sequence: MKKMNLVTAALPYVNNIPHLGNLVQVLSADAFARYSKMSGIKTLYVCGTDEYGTATETKALIENTTPLELCNKYYEIHKSIYKWFNIEFDIFGRTTNKNHQDIVQNFFLQLEKNGYIKERETEQFFCNKDSMFLADRYVIGECPECQSMAKGDQCDNCSKLLNPTDLINPKCIICKNKPILKKTNHLYLDLPKIKTKLEKWIKNPDTSKNWNTNALKMTKAFLRDGLKERAITRDLKWGIPVPKKGFENKVFYVWFDAPIGYISITKNIIKNWESWWKNNDQVNLVQFIGKDNILFHTIIFPCIEIGSEENWTILNQLSSSEYLNYENLKFSKSEGTGIFGNDAITTGIPSDIWRFYIYYNRPEKSDFQFMWQDLMERVNTELIDNFSNLVNRVLTFQRKFFGDVIETIEIQNKFWKQITPKYNKILNLFKKTELKSALKEILKISSLGNKIFQDNEPWKRKNNSPQETKELISNLIYLIRDLSILMMPFIPETSKKIQQFFGNSYQFSTKILGTKSGIKKIEFTEILFNKLEQKKINNLKLKYSGDKNMKENEQAENLPIAKEQPENLFREKVLLRVVKINKIERNPEAKNLFILKLDDGTNKDKQIVSGLEGYYTEEELLGKHIIIVDNLKPAKFRGIKSEGMLIAAEDKNKNFKVIIVEDSIQNPIAGERIILENDQNKDLACPPKIDINKFLKANIVAENGELKINGINLILENSKNKILSKDIPNGTVC
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPT_METPP
Sequence: MTHPKELPLASLQFYATAPYPCSYLAGRQARSQVATPSHLIHADTYSGLVANGFRRSGMFTYRPYCDGCRACVPLRVPVAGFQPSRSQRRAWKAHQGLQSRVLRLCFVPEHYQLYLRYQAGRHAGGGMDHDSIDQYTQFLLQSRVNSRLVEFREPAPEGQLGTLKMVSILDILNDGLSAVYTFYEPDPDASYGTYNVLWQIEQTRQLKLPHVYLGYWIGESPKMSYKAQFRPNERLVDGVWQPEPRDETVGSPRQG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2A_METJA
Sequence: MFIMRREFPEEGDIVIGTVKDVKPYGAFVELLEYPGKEGMIHISEVTSGWVKNIRDHVKVGQRVVAKVLRVDERKGHIDLSLKRVTEQQKRAKVQEWKRFQRASKMLERAAEKLGKSLEEAWEEVGYLLEDEFGELYNAFETMVIEGKEVLDDLEISEEWKNVLYEVAKESIELTNVEVEGVIEMKSYAPDGIKQIKKALTTALKANPYEDVEVKITYIGAPKYRVVVIAPDYKSGEEVFKKVCEKAVATIKKLGGEGTYYRESKK
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit alpha, aIF2-alpha, eIF-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
Protein: TRXX_ORYSJ
Sequence: MASAPSTTASGLAPPPFSSARGARLLPGALLRLPPPPASVGSFRVVGPAAAPPGGRRIASARVRCGAAVRFIGQSEFEAEVLQSDLPVLVDFVADWCGPCRLIAPVVDWAAEEYEGRLKIVKIDHDANPQLIEEYKVYGLPSLILFKDGKEVPGSRREGAITKAKFKEYLEPLLSTSTVA
What is the function of this protein?
Thiol-disulfide oxidoreductase that may participate in various redox reactions.  Possesses insulin disulfide bonds reducing activity.
What are the official names of this protein?
Thioredoxin X, chloroplastic, OsTrxx, OsTrx16.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATX1L_MOUSE
Sequence: MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATTHLPHFVPYASLLAEEATPPPQAASPAQSFNKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQMSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANGQRQRERNVRRESEALDSASSKGESQGLVPVVECMADGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDEPSPLNLSHHNLDHQGEGRGSARNPTELVEKSQARVFYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDPSLLPVGSEILVASSLDLQARATFPDKEPTPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPGQLGTPRERPERTVLGPRDLCDSEGKNQPSGEGSRVGEPSQPEPGAQACWPAPSFQRFSMQGEEARAAMLRPSFIPQEVKLSIEGRSNAGK
What is the function of this protein?
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor.  Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (By similarity).  Can suppress the cytotoxicity of ATXN1 in spinocerebellar ataxia type 1 (SCA1) (PubMed:16121196).  In concert with CIC and ATXN1, involved in brain development (PubMed:28288114).
What are the official names of this protein?
Ataxin-1-like, Brother of ataxin-1.
What is the protein family that this protein belongs to?
Belongs to the ATXN1 family.
What are the subcellular locations of this protein?
Nucleus. Cell projection, dendrite. Note=Forms nuclear foci. Colocalizes with NCOR2 and HDAC3. Distributed beyond the nucleus into the cell body and dendrites in Purkinje cells and in inferior olive cells.
Protein: IF3_STRE4
Sequence: MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADAANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_LEUCK
Sequence: MKIQDFKNKKVMVFGWARSGKAAAQRLVELSAIVTVVNGGAFDTDETIYQKLLAAGVTFINHDDDQAIDKSFDFLVKNPGIPYETAIVKKALVLDIPVLTEVEVALSSFDGRLIAVTGSNGKTTTTSLIRDMLKASGQTVTTAGNIGTPVSEVVGPLTSQDTLLLELSSFQLMGLPDIKPDIALITNIFANHLDYHGDRAHYVAAKYQITKNQTANQKLILNADGADTPDFAAKTQAQVVLFSRDNSSDMAWTDGHDLIIEGEHVMPLTAIKLVGPHNLENILAAITVSKIAGVTNEAIKSVLEVFGGVPHRLQYLLTENGVRYYNDSKATDIEATQTALDSFHEPTIWLAGGLDRGDDLTRLIPNLSHVKLVIAFGETQQKVVAIARQAHKPVITVTSVKEAVPVAISSSSAGDVVLLSPAAASWDQYPNFEVRGDEFVNELKENLGV
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESF12_ARATH
Sequence: MKSQTVLISIFIFSFFALHQCMQMDVGEIEGSNKISIGKCVPAQCSVSFFKRDCWCCFRDQSMCSKTQKECESNPRCPPLKF
What is the function of this protein?
Maternally-contributed central cell peptide regulating suspensor development and correct auxin distribution in early developing embryos.
What are the official names of this protein?
EMBRYO SURROUNDING FACTOR 1.2, Maternally expressed family protein 1.2, Maternally expressed gene 1.2.
What is the protein family that this protein belongs to?
Belongs to the MEG family.
Protein: RLMN_VEREI
Sequence: MSTTNLLEFDRDGLADFCARLGEKRFRATQLFRWIHQRGASDFDAMSDLARALRDKLKGCARVQAPPVISGQASADGSVKWLFDVGAGNAVEAVFIPEDERGTLCVSSQAGCAVGCRFCSTGHQGFSRNLSSGEIIAQLWFAEHALRRRLKTEDRVISNLVMMGMGEPLQNLAALLPALRVMLDDHGYGLSRRRVTVSTSGVVPMIDRLARDCPVALAVSLHAPNDALRDQLVPLNRKYPIDELLQACKRYLAHAPRDFITFEYCMLDGVNDQIGHARQLVELVGRAAIRCKFNLIPFNPFPASGLLRSAHDQILAFAQVLGAAGIVTTVRKTRGDDIAAACGQLAGDVRDRTRVAERMAKQRTMQLQLQLNSSRRAEPSAAGVIGCGESI
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1532_SERP5
Sequence: MNISKAEQRVLHVLAKGGYIAFTRDDAGRVTHVQCLTREGLGLADCSLAVFTKLKTKRLILSRQGRPYRVTIDGLKAVRAQLDNR
What are the official names of this protein?
UPF0386 protein Spro_1532.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: SYS_BURCH
Sequence: MLDIQLLRKDLDGVAKRLADRGYTLDVAAFSALEAERRAIQTHTEELQARRNSLSKQIGAMKGKGEDTSAVMAEVGGIGDDMKASEAKLGEIQARLSDLMLGMPNVAHESVPVGKDEADNVEARRWGTPRQFDFEVKDHVDVGTPLGLDFETGAKLAGARFTMLRGPIARLHRALAQFMIDTHTQQHGYTETYTPYIVNPEILYGTGQLPKFADDMFRVEKGGAENTVTQYLISTSEISLTNTVRESIVDASALPIKLTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQVVAPETSYAALDEMVGHAEAILQKLGLPYRVITLCTGDMGFSAAKTFDLEVWLPAQNTYREISSCSNTEAFQARRMQARFRNAQGKPELVHTLNGSGLAVGRTLVAVLENYQNADGSVTVPEVLRPYMGGMERIDAPAQAS
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCA4_RICFE
Sequence: MSKDSDNPGYESGYESDTEEKKQEQAVPAQPISSTANKDGNPDTSEFDPLANKEYTEEQKQKLEQEQKEYFSQTTPQELEADDGFSFTPASSTQSTPSISSLSGGISSDSQTSDPITKAVRETIIQPQKDEIAEQILKDLAALADRDLAEQKRKEIEEEKDKTLSAFFGNPANREFIDKALENPELKKKLESIEIAGYKNVLSTYSAANGYQGGFKPVQWENQISASDLRATVVRNDAGDELCTLNETTVKTKPFTVAKQDGTQVQINSYREIDFPIKLDKADGSMHLSMVALKADGTKPSKDKAVYFTAHYEEGPNGKPQLKEISSPKPLKFAGDGPDAVAYIEHGGEIYTLAVTRGKYKEMMREVELNQGQSVDLSQTIAEDLTKVQGRSQETPQPIITPNQELKSSIETPTTTQVPPITPANQPLQPETSQMPQPQQVNPNLLNAATALSTSMQDLLNYVNAGLTKEKDGNKQIDLINEAATAILNNEKSDIAEKQANIIALTENTVNNNDLTPDTKVAGVNAVLETIKNDQNTPDLEKSKMLEATVAIALNSENLEPKQKQQMLEKAVDVGLSLKDDASRVTAIDGITDAVIKSNLSTEDKGTMLIAVGDKVNASELSNAEKQKLLGSVLKKGVEAQVLSPEQQQLMQQNLDKITAEQTKNAQITEVQGILANPAFNTIAKTEAIQNVTTKVLDSPIKAEIKGETLESITKVVAESPLNGQDKADIVKGMGEAIASHKTMAPTEKISTIESVEKGVAESITDLEDKKLMTKGLVEGIYEGKANPEITSEKTKAVSRGIDKSTAIPEDKQALKDAANEAALDRETQNLTEGLKRQNLGEPKPRDDIYNKAQDVADALKNVITPVLDAHPEKREVSEEEEVVKKTSSILNDISKLAIEKVNNFRAMLSPDGNLKTLEEKKAESTKKVDELVKEFGTKSSTEEQQSFIKANLIDDKTLSKEIRLQTINKLLQEQAQKRAEAIENPNVKTEDVRVVSGVNIKDNIKIMGALMNARDSIIQSENLNKSTPIKRESSFPPR
What are the official names of this protein?
Antigenic heat-stable 120 kDa protein, 120 kDa antigen, Protein PS 120, PS120.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN220_HUMAN
Sequence: MDLHRAAFKMENSSYLPNPLASPALMVLASTAEASRDASIPCQQPRPFGVPVSVDKDVHIPFTNGSYTFASMYHRQGGVPGTFANRDFPPSLLHLHPQFAPPNLDCTPISMLNHSGVGAFRPFASTEDRESYQSAFTPAKRLKNCHDTESPHLRFSDADGKEYDFGTQLPSSSPGSLKVDDTGKKIFAVSGLISDREASSSPEDRNDRCKKKAAALFDSQAPICPICQVLLRPSELQEHMEQELEQLAQLPSSKNSLLKDAMAPGTPKSLLLSASIKREGESPTASPHSSATDDLHHSDRYQTFLRVRANRQTRLNARIGKMKRRKQDEGQREGSCMAEDDAVDIEHENNNRFEEYEWCGQKRIRATTLLEGGFRGSGFIMCSGKENPDSDADLDVDGDDTLEYGKPQYTEADVIPCTGEEPGEAKEREALRGAVLNGGPPSTRITPEFSKWASDEMPSTSNGESSKQEAMQKTCKNSDIEKITEDSAVTTFEALKARVRELERQLSRGDRYKCLICMDSYSMPLTSIQCWHVHCEECWLRTLGAKKLCPQCNTITAPGDLRRIYL
What is the function of this protein?
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity).  Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658, PubMed:33964137).  Plays a critical role in the regulation of nuclear lamina (PubMed:33964137).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF220, RING finger protein 220, RING-type E3 ubiquitin transferase RNF220.
Protein: LRRN1_HUMAN
Sequence: MARMSFVIAACQLVLGLLMTSLTESSIQNSECPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPSNLSSDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPLRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYKGHQVKEVLIQDSSEQCLPMISHDSFPNRLNVDIGTTVFLDCRAMAEPEPEIYWVTPIGNKITVETLSDKYKLSSEGTLEISNIQIEDSGRYTCVAQNVQGADTRVATIKVNGTLLDGTQVLKIYVKQTESHSILVSWKVNSNVMTSNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSNIHQQTQKSCVNVTTKNAAFAVDISDQETSTALAAVMGSMFAVISLASIAVYFAKRFKRKNYHHSLKKYMQKTSSIPLNELYPPLINLWEGDSEKDKDGSADTKPTQVDTSRSYYMW
What are the official names of this protein?
Leucine-rich repeat neuronal protein 1, Neuronal leucine-rich repeat protein 1, NLRR-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ULAG_ECOL6
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGANVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGTLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGN1_SCHPO
Sequence: MKLVLFLVLLFSALINLTNADKMVVAHFIVGNTYPYTVSNWEEDIQDAIAVGIDGFALNMGSDAWQVERIEDAYDAAASVSSDFKLFISFDMSIISADADFIEGVVRRFADKPNQLYYDGKVFVSTFAGETDTFGYSDVSTGWDSAVKEPLASAGYPIYFVPSWTSLGQGALEESVADGFLSWNAWPTTDADMNDNDDIGYQNLANSLGKLYVAPVSPWFYTHLSYKNWAYKSDWLIIDRWNEMLSVQPDMIEVLTWNDYGESHYIGNIQGALPAGSEGYVDGFDHTAWRYLMSPYISAYKLGLSEPYINFESLFYWYRPTPKSATATADSLSYPSGGDYMEDEIFVLVYLLQSAEVTVTCGSTTQTFSGVPGVNQFTIPMETNASPSFTVARQGGTLASGTGPEIVDSLSIYNFNAYTGVLYF
What is the function of this protein?
Has a role in cell separation where it is required for the degradation of the cell wall material surrounding the septum (the septum edging) which must be hydrolyzed before full separation of the daughter cells can occur.  Hydrolyzes 1,3-alpha-glucan predominantly into pentasaccharides.
What are the official names of this protein?
Glucan endo-1,3-alpha-glucosidase agn1, Endo-1,3-alpha-glucanase agn1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 71 family.
Protein: ISPG_NOSP7
Sequence: MQTLPIVDTSNTASSQHIFDTTIKRRKTRPVKVGNVTIGGGYPVVVQSMINEDTLDIDGSVAGIRRLHEIGCEIVRVTVPSMAHAKALAEIKQKLIKTYQDVPIVADVHHNGLKIALEVSKHIEKVRINPGLYVFEKPNVNRTEYTQSEFDEIGDKIRETLEPLVVSLRDQGKSMRIGVNHGSLAERMLFTYGDTPEGMVESAIEFIRICESLDFRNLVISMKASRVPVMLAAYRLIAKRMDELGMDYPLHLGVTEAGDGEYGRIKSTAGIATLLADGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTLFNLEEVLHKVREATKHLTGLDIAVMGCIVNGPGEMADADYGYVGKTPGYISLYRGREEIKKVPEDKGVEELINLIKADERWVEP
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: HSCB_ACIB5
Sequence: MNHFELFNLPVALDIDLASLKSNFLSLQQQYHPDKAADKDQALIKSSEINQAFKTLSQVDSRAAYLLALKKQDHHLDQSISDFEFLQSALELREQLDEATSSEHLRTLRLEVQQWIDGLVREFKIDYSEEDWAEARDTVRKLRFFQRVLNDIDKAEDQLLDDEDSFDLDDDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: Y1276_AZOVD
Sequence: MRVIIVSGRSGSGKSTALNVLEDNGFFCIDNLPAVLLPELAERALLHTELLEPQVAVSIDARNLPSQLKRFPELLAEVRTRYILCDLLYLDADDKTLLKRFSETRRRHPLTNENRSLAEAIRDEGRLLTPIKDLADLKIDTTHLNLYQLRDTLKLRLLNKPEPGTAFLIESFGFKKGMPVDADLVFDVRCLPNPYWKPDLRDFSGLDQPVADYLAVQPDVEEMYQDILTYLQKWLPRFAASNRAYVTIAIGCTGGHHRSVYLADRLGQALKQSLKNVQVRHRDLC
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Avin_12760.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: GLGA_METJA
Sequence: MKIVILAPTITPIVSYGGLGDVMRDLPKFLKKGNEVVVLTLNHYNRYFTLPYEDIKKITVIYKGAKITFDVLRTKHPTTGVDLIVFSNESVNNLNVWDPIKYEIFADLVITYLDEVKDIDVVSGHDWMCGLAIAKCNDILDLPTTLTIHNEAFKGEMIEYKGEVMTFLELGIKYADAVNTVSPSHAEEIKNYPYIKKYLNNKPFCGILNGIDIDEYDPMKIIERMCNLSNNKLDPRNYAYISPYSAEDSHNIKPKIKYSWFYRGGVYEYVEDWNKIDKGISATDVEVHGGVDGDIETPLIGFVGRATHQKGFNTMFEAIPELLEKHDIRFVFLTKGDRDIEERLKNLANEHDGRILALIGYSLPLSSLVFAGSDWIIMPSYWEPCGLVQMEAMAYCTPVIATETGGLKDTIIPLHPNPYEHPNFDKATGVLFKVPDKVGFMWGVEHALNWTFYKLNEICMFMQYIRYKCPKHPYDENSPLSMMMKNCYYHVFRNLSWQNSPSIRKYKGLFGGAIYNHYLQP
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Probable glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.