PharMolix/UniProtQA huggingface dataset:
Protein: FMO5_RAT
Sequence: MAKKRIAVIGSGASGLTCIKCCLEEGLEPVCFERSDDIGGLWRYQENPEKGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNSQVLEYFRMYAKEFGLLKYIQFKTTVCSVKKQPDFSTSGQWQVVTEHEGKQQVDVFDGVLVCTGHHTDPHLPLDSFPGIEKFKGKYFHSREYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKRGYPIDILLSSRITNYLSKICGSALKNRYMEKQLNQRFDHEMFGLKPKHSALGQHPTINDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDVVIFATGYSFAFPFLEDSVKVVQNKVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKKLPSQSEMMAEINKTREEMAKRYVDSQRHTIQGDYIDTMEEIADLVGVRPNLLSLAFTDPKLAFQLLVGPCTPVQYRLQGPGKWAGARKTILTTEDRIRKPLMTRVVERDSSGTSLVTVRVLMLAVTFLAVILAYF
What is the function of this protein?
Acts as Baeyer-Villiger monooxygenase on a broad range of substrates.  Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters.  Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive.  In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms.  Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline.  Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity (By similarity).  Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects (By similarity).
What are the official names of this protein?
Flavin-containing monooxygenase 5, FMO 5, Dimethylaniline monooxygenase [N-oxide-forming] 5, Dimethylaniline oxidase 5, Hepatic flavin-containing monooxygenase 5, NADPH oxidase.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Microsome membrane. Endoplasmic reticulum membrane.
Protein: BIOF_RALSO
Sequence: MRLLDDLRAGLDAIDAAHLRRVRRTAYSPTDRSQRIDVPGGEPREILGFCGNDYLGLAAHPALMQAVGEGARRYGFGSGASHLVSGHSVAHARLEARMAALQAPHIPDADALCFCTGYMANMAVVSAMAQAGGIQPAQDCTVFSDALNHASLIDGARLSRAAVKVYPHVDLAALEAQLAACGSRNKLIVTDGVFSMDGDIAPLPELLALAERFDAWLIVDDAHGLGVLGADGVGVLSHFGLRSERLIYIGTFGKAAGGAGACVVAHRMAVDWLVQRARTYIFTTATPPAVACGVEAALDLIAGEEGAARRARLAGHIARWSDHAQRLAARFGWQWMPSPTAIQPLVIGENAPALALAAALEREGIRVAAIRPPTVPAGTARLRITLSAAHTEDDIERLARALEAAGQSQQSAARAA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: UPP_ALIFM
Sequence: MKVVEVKHPLIKHKIGLMREGEISTKRFRELATEVGSLLTYEATSDFETEKVTINGWNGPVEVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFNKLASNIDERIALVVDPMLATGGSMIATLDLLKEKGCKHFKVLVLVAAPEGIEALEKAHPDVELYTAAIDEKLNDKGYIVPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: MUTL_BEII9
Sequence: MTIRRLDPVLIDRIAAGEVIERPAAAVKELVENALDAQASEIDVVLEGGGKTLIRVTDNGCGMSAEDLELSVERHATSKLPDGDLFAIATLGFRGEALPSIGSVSVLSLTSRMETATHGVALSVEHGRKQTVIPCGQPRGTRIEVRELFRTTPARLKFLKGDRAEARAAADAVQRLAMAHPTRRFTFTSTDTAGFDYLPCAEGPEGLLARIGAVLGKDFEANALPVEAEREGIILEGFIGLPTWHRANGLAQYLFVNGRPVRDKLLTGAVRAAYMDYLPAGRYPALALFLRCDPQEVDVNVHPAKAEVRFRDQGLVRGLLVGALKQTLQQAMHRATPDGGRVALGLLAMHSAGQGQRPVSSASMPSASRQAPTMPPRDWIKEGVQDWDWRQSPARPQNPPQNPPPGDRIEMSGSLPLGFAETPAGLNGDSGKELSEAASETPHDEPLGFARAQLHETYIVAQTRDGFVLVDQHAAHERLVYERLKQARAAQTVERQILLLPTIVELPEADVERLVDAASMLADFGLVVESFGPGALAVREIPIVLKDGSVPALIHDLANQLQEDDKALIPLERKLDHVLATFACHHSVRAGRRLGIEEMNALLREMERTPGSGQCNHGRPTYIELKLGDIERLFGRG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RF1_STRCO
Sequence: MFEAVEELVAEHADLEKKLADPSVHSDQANARKLNKRYAELTPIVATFRSWKQTGDDMETAREFAADDPDFAAEVKELDKQRDELTEKLRLLLVPRDPSDDKDVILEIKAGAGGDESALFAGDLLRMYLRYAERIGWKTEIIDSTESELGGYKDVQVAVKTKGGQGATEPGQGVWARLKYEGGVHRVQRVPATESQGRIHTSAAGVLVTPEAEEIDVEINPNDLRIDVYRSSGPGGQSVNTTDSAVRITHIPTGVVASCQNEKSQLQNKEQAMRILRSRLLAAAQEEAEKEAADARRSQVRTVDRSEKIRTYNFPENRISDHRVGFKAYNLDQVLDGDLDSVIQACVDADSAAKLAAA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_BARBK
Sequence: MNTQDVINIFKQADAILEGHFILTSGRHSATFLQKAKVFMHADLTEKLCRGLAQEIKRHVEGKIDYVVGPAIGGLIPSYETSRHLGVPSIWVERENGVFRLRRFEVEKGARVVIVEDIVTTGLSIRETIEALVAVEADVVASACIIDRSGGKVDVGVPLIALAEYEIVSYTRDTLPHELSKIPAVKPGSRDI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: DIVJ_CAUVC
Sequence: MILPTALKSRLALEFETLPDPFRRPAARAAGLDPAHAWRLGWLAAVCLAAAAALFTADSGGWPVWAALGAGALPALVSLIFTREDERTQSWLLVLWAVGGSLAAVLTGGVGGAMAAWCLAPVAAASTQDQPKRLAEGAALALIGACVAALTQLSGLAPAAPTGPLAFVLGFLALVTTGLGLAAGLLIGRRRQGARDDRYASEIIGLETLLDGLPHLAIAVRGQGQVTAVRGAAPPGVTRADLVNRGLTGAAAPGDRQRLTAAIAQAHREGSASLTFNPALGVERVVALDMHRVAPNQLVGVLRDITVERHREHALDQARIDAEALAAGRARFLANMSHELRTPLNAIMGFSDIMRARMFGPLSDRYAEYAELIHESGGHLLDLINDVLDMSKIEAERFELQRGVFDAREAVQAAMRLLRVQSDTAGVQLRGVLPPGELEVDADRRALKQIVLNLVSNALKFTPRGGQVTVTAHGYDGVLEIVVADTGVGISPEDLERLGRPYEQAGGAEQRARGTGLGLSLVRAFAQLHGGEMVIESRLGAGTTVSVRLPVLLAPMVAATPTPPAAPEAPSAPEPAPTVEEPPPASLGDNVIAFAPR
What is the function of this protein?
Kinase required for the regulation of cell division and differentiation.  Is part of a signal transduction pathway, activating PleD by phosphorylation.
What are the official names of this protein?
Histidine protein kinase DivJ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HOX1A_MAIZE
Sequence: MEKNIAHCPVEGNGEIENGASSSQNPESLEHSVLLSTSQTMPNNLGIRKNYKRAANRGKKGSQGLTGQAYTLMSSNSDVRVLRSTSSSKTTSTEHVQAPVQPAAKRRKMSRASNKSSTDEFSQIRKRVRYILNRMNYEQSLIEAYASEGWKNQSLDKIRPEKELERAKSEILRCKLRIREVFRNIDSLLSKGKIDETLFDSEGEISCEDIFCSTCGSNDATLGNDIILCDGACDRGFHQNCLNPPLRTEDIPMGDEGWLCPACDCKIDCIDLINELHGSNISIEDSWEKVFPDAAAMANDSKQDDAFDLPSDDSDDNDFDPNMPEEHVVGKDEESSEEDEDGGSDSDDSDFLTCSDDSEPLIDKKVDDLRLPSEDSEDDDYDPAGPDSDKDVEKKSSSDESDFTSDSDDFCKEISKSGHDEVSSPLLPDAKVGDMEKITAQAKTTSSADDPMETEIDQGVVLPDSRRRQAERLDYKKLYDEAYGEASSDSSDDEEWSGKNTPIIKSNEEGEANSPAGKGSRVVHHNDELTTQSTKKSLHSIHGSVDEKPGDLTSNGSNSTARKGHFGPVINQKLHEHFKTQPYPSRSVKESLAEELGLTFRQVNKWFETRRHSARVASSRKGISLDKHSPQNTNSQVTASMEPKEPEGTVVEESNVCLNGGTTISKEAVSSKVGSRTPGSDVGGSKVDSAEDQNPGPDLAEKARQKAIQQELRKKKMGR
What is the function of this protein?
Interacts with the shrunken (SHR) 26 bp feedback control element.
What are the official names of this protein?
Homeobox protein HOX1A.
What is the protein family that this protein belongs to?
Belongs to the PHD-associated homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CA1C_CONLI
Sequence: AGNAKMSALMALTIRGCCSHPVCSAMSPICG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin inhibits alpha-3-beta-4, alpha-6/alpha-3-beta-4, and alpha-2-beta-4 nAChRs.
What are the official names of this protein?
Alpha-conotoxin Li1.12, Livi_23.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CATA_ACIAD
Sequence: MEVKIFNTQDVQDFLRVASGLEQEGGNPRVKQIIHRVLSDLYKAIEDLNITSDEYWAGVAYLNQLGANQEAGLLSPGLGFDHYLDMRMDAEDAALGIENATPRTIEGPLYVAGAPESVGYARMDDGSDPNGHTLILHGTIFDADGKPLPNAKVEIWHANTKGFYSHFDPTGEQQAFNMRRSIITDENGQYRVRTILPAGYGCPPEGPTQQLLNQLGRHGNRPAHIHYFVSADGHRKLTTQINVAGDPYTYDDFAYATREGLVVDAVEHTDPEAIKANDVEGPFAEMVFDLKLTRLVDGVDNQVVDRPRLAV
What are the official names of this protein?
Catechol 1,2-dioxygenase, 1,2-CTD.
What is the protein family that this protein belongs to?
Belongs to the intradiol ring-cleavage dioxygenase family.
Protein: THIC_ECOSE
Sequence: MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ZN554_HUMAN
Sequence: MVTCAHLGRRARLPAAQPSACPGTCFSQEERMAAGYLPRWSQELVTFEDVSMDFSQEEWELLEPAQKNLYREVMLENYRNVVSLEALKNQCTDVGIKEGPLSPAQTSQVTSLSSWTGYLLFQPVASSHLEQREALWIEEKGTPQASCSDWMTVLRNQDSTYKKVALQEEPASGINMIKLIREDGGWKQLEDSHEDPQGLLSQKASLHVVAVPQEKATAWHGFGENGNLSPALVLSQGSSKGNHLCGSELDITSLASDSVLNHHQLGYADRRPCESNECGNAIRQNSHFIQHGGKMFVYLENGQSLNHGMALTIHNKINTAEKPFECHQCGKVFNRRHSLSEHQRIHTGEKPYECQECGRAFTHSSTLTRHLRTHTGEKPYGCGECGKAFNRISSLTQHQRIHTGEKPYKCEDCGKSFCQSSYLILHKRTHTGEKPYECSECGKAFSDRSSLNQHERTHTGENPYECKQCGRAFSQRSSLVRHERTHTGEKPYRCQECGKAFSQSSSLVTHQKTHSSQKTYKIIDCGKAFYQNRHLIGY
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 554.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UGPC_BRADU
Sequence: MANVTLRNVRKTYTGGFEAIKGVNVDVADGQFCVLVGPSGCGKSTLLRMVAGLETVTGGEIDIGGRVVNQIEPADRDIAMVFQNYALYPHMSVYNNMAYGLRNRGMAEAEIKTRVEEAARVLELTSMLERKPRQLSGGQRQRVAMGRAIVRQPKVFLFDEPLSNLDAKLRIAMRVEIRKLQRRLNTTSIYVTHDQLEAMTLADVLVVMNGGQVEQVGNPLAIYEKPATTFVASFIGAPPMNLMSTRSDEIKSQLGGSAAEAGVLGIRPEDFVITDQTPAGGVALPLTVEAIERVGAETFVYGSREQEDQRVAATPGELPPGEVIVRIPGTEAPTIGARIRVAAIRPKLHLFSGDGRTRLEA
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PS1C2_HUMAN
Sequence: MILNWKLLGILVLCLHTRGISGSEGHPSHPPAEDREEAGSPTLPQGPPVPGDPWPGAPPLFEDPPPTRPSRPWRDLPETGVWLPEPPRTDPPQPPRPDDPWPAGPQPPENPWPPAPEVDNRPQEEPDLDPPREEYR
What are the official names of this protein?
Psoriasis susceptibility 1 candidate gene 2 protein, Protein SPR1.
What are the subcellular locations of this protein?
Secreted.
Protein: NNRD_NEIMB
Sequence: MFPVFHLSGESRRQMLQTALRFPHVFKARAEDSHKGTFGTLAVVGGSAGMSGAPVLAASAAMYLGCGKVWAGFNQDTLPFAVIAGFPEIMLDTADSLAKRQDINAWVVGCGLGTGRAAVGTLAGILTEHTDKPVVLDADALNILSTDAETRNLARGCKNLILTPHPAEAARLLGTTVAQVQADRTAAVRKIGAIFGATVVLKGHKTLVASPDTEIYVNESGNAGLATAGSGDVLGGIIGSLLAQGVPVFEAACAGAWLHGAAADVIKESAGIAAGLLAGEIAPAARWLRNRITKSM
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ADP-dependent (S)-NAD(P)H-hydrate dehydratase, ADP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
Protein: PDXH_RHOPS
Sequence: MSDTSIQQQSQLTSGDFTAAENPFALFAEWFADANESELNDPNAMALATVDPDGLPDVRMVLMKGYDTDGFVFYSHIASQKGRELAANPKAALLFHWKSLRRQVRIRGAVSAVTETEADDYFATRPKQAQIGAWASKQSQPLESRFAFEQAIAKVAARYLVGEVPRPPGWSGWRITPLRFEFWHDRPFRLHDRIEFSRDTPAQPWIKTRLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: MOAC_SALCH
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIVDGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEIQLQAEPEHNRVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVDAHD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: DCUP_PSEP1
Sequence: MTALKNDRFLRALLKQPVDVTPVWMMRQAGRYLPEYRASRAKAGDFMSLCMNPQFACEVTLQPLDRYPLDAAILFSDILTIPDAMGLGLYFETGEGPRFKKVISTPADIEALPVPDPQKDLGYVMDAVSTIRRELNGRVPLIGFSGSPWTLATYMVEGGSSKDFRKTKAMAYDNPQALHLLLDKLAQSVTSYLNGQILAGAQAVQIFDTWGGNLSAAAYQEFSLAYMRKIVSGLIREHEGRKVPVILFTKNGGLWLESIADAGADALGLDWTCEIGDARRRVGDKVALQGNMDPTVLYAKPEAIRKEVARILASYGHGTGHVFNLGHGITPEVDPEHAGVFINAVHELSAQYHQ
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_STAA9
Sequence: MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSRDIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPGNAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB3B_BOVIN
Sequence: MASVTDGKAGVKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGRLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDTLDTDPSLLGTSKNTRLSDTPPLLQQNCSC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein Rab-3B, SMG P25B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Note=Colocalizes with GAS8/DRC4 in the Golgi apparatus.
Protein: PGLRX_ASPNG
Sequence: MRLTHVLSHTLGLLALGATAEAFSRSREAACSPKKPFRPLPTSSSRDKTCHVRSHGDGSDDSDYILSALHQCNHGGKVVFDEDKEYIIGTALNMTFLKNIDLEVLGTILFTNDTDYWQANSFKQGFQNATTFFQLGGEDVNMYGGGTINGNGQVWYDLYAEDDLILRPILMGIIGLNGGTIGPLKLRYSPQYYHFVANSSNVLFDGIDISGYSKSDNEAKNTDGWDTYRSNNIVIQNSVINNGDDCVSFKPNSTNILVQNLHCNGSHGISVGSLGQYKDEVDIVENVYVYNISMFNASDMARIKVWPGTPSALSADLQGGGGSGSVKNITYDTALIDNVDWAIEITQCYGQKNTTLCNEYPSSLTISDVHIKNFRGTTSGSEDPYVGTIVCSSPDTCSDIYTSNINVTSPDGTNDFVCDNVDESLLSVNCTATSD
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Exopolygalacturonase X, ExoPG, Galacturan 1,4-alpha-galacturonidase, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_EDWI9
Sequence: MMAEKHGVLLVNLGTPSAATPAAVKAYLAEFLSDRRVVDLPSWQWQPLLRGLILPRRAPRVARLYQSIWTAQGSPLLYYSQRLCDGLQARLGEAIPVVLGMSYGEPSLDRALSALSDAGVTQLTVVPLYPQYSCSTSAAVFDGVAAWLARQRCIPALRFVRDYAQHPAYIAALCQRIRCSIAEHGQPDILLFSYHGIPQRYAAEGDDYPQRCLATTQAVVQALGLMPSQYAVSFQSRFGREPWLTPYTDETVVALATGGVRHLQVICPGFAADCLETLEEIAVQNREAFLAAGGHHFAYIPALNDDDMQITLLQQLVAATPA
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LN28A_DANRE
Sequence: MPPANPHLNHTGGCTKTEEEEAASSEEDSGSFHGSGVCKWFNVRMGFGFLSMTHREGICLDSPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKRSSKGLESLQVTGPGGAPCVGSEKKPKGTQKRRSKGDRCFNCGGPNHHAKECQLPPQPKKCHFCQSISHMVANCPIKAQQLSPGSQGKSTTSTGEEEDMSHTPLLPESTD
What is the function of this protein?
RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism.  Seems to recognize a common structural G-quartet (G4) feature in its miRNA and mRNA targets (By similarity).  'Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis.  Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization.  Suppressor of microRNA (miRNA) biogenesis, including that of let-7.  Binds specific target miRNA precursors (pre-miRNAs), recognizing an 5'-GGAG-3' motif found in their terminal loop, and recruits uridylyltransferase.  This results in the terminal uridylation of target pre-miRNAs.  Uridylated pre-miRNAs fail to be processed by Dicer and undergo degradation (By similarity).  Localized to the periendoplasmic reticulum area, binds to a large number of spliced mRNAs and inhibits the translation of mRNAs destined for the ER, reducing the synthesis of transmembrane proteins, ER or Golgi lumen proteins, and secretory proteins.  Binds to and enhances the translation of mRNAs for several metabolic enzymes, increasing glycolysis and oxidative phosphorylation.  Which, with the let-7 repression may enhance tissue repair in adult tissue (By similarity).
What are the official names of this protein?
Protein lin-28 homolog A, Lin-28A.
What is the protein family that this protein belongs to?
Belongs to the lin-28 family.
What are the subcellular locations of this protein?
Cytoplasm. Rough endoplasmic reticulum. Cytoplasm, P-body. Cytoplasm, Stress granule. Nucleus, nucleolus. Note=Predominantly cytoplasmic. In the cytoplasm, localizes to peri-endoplasmic reticulum regions and may be bound to the cytosolic surface of rough endoplasmic reticulum (ER) on which ER-associated mRNAs are translated. Shuttle from the nucleus to the cytoplasm requires RNA-binding.
Protein: POED2_ORYSI
Sequence: MESEGWPALQPLLCFAWIAATLPIIAAALPIPTAVGGHLLRRLLSAFSSRGKTVRPSPASSSGSSSSKAKFTVPQKYFMHFYVVGVLATTILLLAIWFYAYMKLTPLLLESSSYSTIFSHLVGSNSFSFGRVRSRTMGHKYRVWRTVFALLLMEVQVLRRLYETEHVFHYSPARMHIVGYLTGLFYYVAAPLSLASSCIPEAAEYFQGQVPEFVVKGRARMPDLVIDSSSLLQPLLKLGWTQWIGAVIFIWGSLHQIRCHAILGSLREHKDSDEYVIPCSDCFNRVSCPHYLAELVIYFGMLVASGAEDIPVWFLFIFLITNLSFAAVETYNWYLQKFEDYPRSRYAIIPFVC
What is the function of this protein?
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol.  Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.  Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (By similarity).
What are the official names of this protein?
Polyprenol reductase 2.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IF12_DESVH
Sequence: MAADDHIEMEGVVEEALPGTLFRVVLENGHEVLAHLCGKMRKFRIRVLPGDKVTVHISPYDLTKGRIARRTTTPSGGPRPARSGNRR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_PSEF5
Sequence: MIPLILAVSAGGVAGTLLRFATGNWINANWPRHFYTATLAVNIVGCLLIGVLYGLFLVRPEVPIEVRAGLIVGFLGGLTTFSSFSLDTVRLLESGQVALALGYAALSVFGGLLATWAGLSLTKL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FAR2_PENMO
Sequence: AYSNLNYLRF
What are the official names of this protein?
FMRFamide-like neuropeptide FLP2, AYSNLNYLRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.