PharMolix/UniProtQA huggingface dataset:
Protein: EP1G_DAUCA
Sequence: MARFFPLTLTILLFFIQRIDFCHTLVPANETFKFVNEGELGQYISEYFGDYRPLDPFTSPFQLCFYNQTPTAFTLALRMGLRRTESLMRWVWEANRGNPVDENATLTFGPDGNLVLARSNGQVAWQTSTANKGVVGLKILPNGNMVLYDSKGKFLWQSFDTPTDTLLVGQSLKMGAVTKLVSRASPGENVNGPYSLVMEPKGLHLYYKPTTSPKPIRYYSFSLFTKLNKNESLQNVTFEFENENDQGFAFLLSLKYGTSNSLGGASILNRIKYNTTLSFLRLEIDGNVKIYTYNDKVDYGAWEVTYTLFLKAPPPLFQVSLAATESESSECQLPKKCGNFGLCEESQCVGCPTSSGPVLAWSKTCEPPKLSSCGPKDFHYNKLGGWITT
What is the function of this protein?
May be involved in the limitation of water flow through the outer epidermal cell wall, either by direct modification of wall structure or as a signal instructing the protoplast to restrict water transport across the cell wall.
What are the official names of this protein?
Epidermis-specific secreted glycoprotein EP1, 52/54 kDa medium protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RNMT_MYCTO
Sequence: MGLVWRSRTSLVGQLIGLVRLVASFAAQLFYRPSDAVAEEYHKWYYGNLVWTKTTYMGINCWKSVSDMWNYQEILSELQPSLVIEFGTRYGGSAVYFANIMRQIGQPFKVLTVDNSHKALDPRARREPDVLFVESSSTDPAIAEQIQRLKNEYPGKIFAILDSDHSMNHVLAEMKLLRPLLSAGDYLVVEDSNINGHPVLPGFGPGPYEAIEAYEDEFPNDYKHDAERENKFGWTSAPNGFLIRN
What is the function of this protein?
Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).
What are the official names of this protein?
Rhamnosyl O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the rhamnosyl O-methyltransferase family.
Protein: RS3_ACIC5
Sequence: MGQKVHPYGFRLGVNKPWRSRWFVERDYDKLLVEDVHLKRELKEKLKAAGVSSVEVERPGNKLRLIIRTARPGIIIGRKGAEIEKLKADLQKRTNREVFIDILEVNKPELDAQLIAENIALQLEKRVGFRRAMRKAVDSALRFGCKGIKVRVSGRLNGNEIARSEWYLQGRLPLHTLRADIDYGFAEAHTTYGIIGVKTWVYRGDIYQQRRREPQAAVGTSVF
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RS12_PARP8
Sequence: MPTINQLVRKGRTSETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRKQARSKYGAKRAKAGK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: LCK2_RHYMA
Sequence: DPGFSSWG
What is the function of this protein?
This cephalomyotropic peptide stimulates contractile activity of cockroach protodeum (hindgut).
What are the official names of this protein?
Leucokinin-2, Leucokinin II, L-II.
What are the subcellular locations of this protein?
Secreted.
Protein: SNF1_YEAST
Sequence: MSSNNNTNTAPANANSSHHHHHHHHHHHHHGHGGSNSTLNNPKSSLADGAHIGNYQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWFKVDLPEYLLPPDLKPHPEEENENNDSKKDGSSPDNDEIDDNLVNILSSTMGYEKDEIYESLESSEDTPAFNEIRDAYMLIKENKSLIKDMKANKSVSDELDTFLSQSPPTFQQQSKSHQKSQVDHETAKQHARRMASAITQQRTYHQSPFMDQYKEEDSTVSILPTSLPQIHRANMLAQGSPAASKISPLVTKKSKTRWHFGIRSRSYPLDVMGEIYIALKNLGAEWAKPSEEDLWTIKLRWKYDIGNKTNTNEKIPDLMKMVIQLFQIETNNYLVDFKFDGWESSYGDDTTVSNISEDEMSTFSAYPFLHLTTKLIMELAVNSQSN
What is the function of this protein?
Serine/threonine protein kinase essential for release from glucose repression (PubMed:3526554, PubMed:6366512, PubMed:3049551, PubMed:1944227, PubMed:8289797, PubMed:8628258, PubMed:25869125).  Catalytic subunit of the AMP-activated protein kinase complex also known as the SNF1 kinase complex (Snf1c), a central regulator of cellular energy homeostasis, which, in response to a fall in intracellular ATP levels, activates energy-producing pathways and inhibits energy-consuming processes (PubMed:8289797, PubMed:26667037).  The complex phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, leading to transcriptional activation through TBP recruitment to the promoters (PubMed:15719021).  The complex also negatively regulates the HOG1 MAPK pathway in ER stress response including unfolded protein response (UPR) (PubMed:25730376, PubMed:26394309).  Under nutrient/energy depletion, the complex phosphorylates and activates PAS kinase PSK1 which in turn activates PBS1, leading to the inhibition of the TORC1 signaling pathway (PubMed:25428989).  SNF1 also interacts and phosphorylates adenylate cyclase CYR1 and negatively regulates the protein kinase A signaling pathway (PubMed:26309257).  Also phosphorylates and regulates the transcriptional activator CAT8 (PubMed:15121831).
What are the official names of this protein?
Carbon catabolite-derepressing protein kinase, Sucrose nonfermentating protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus membrane; Peripheral membrane protein. Note=Nuclear translocation occurs under nitrogen and glucose starvation conditions (PubMed:25869125).
Protein: HRCA_CHLCH
Sequence: MDYRELTARERQILGIIIQSYVVSAAPVGSKYIARHYNLGLSDATIRNVMAELEELGFISQPHTSAGRVPTDKGYRYYVDLIMTVKTLDEQEKQRFEQHITPLERKGTSADVLLSAVKVLGTISRQLSVVLSPTLSNALFEKLDMVLLSSTRMMVIISIQSLFVKTIVMELHMQVSRQMLDEVVDVLNERLSGLTLSEIRRSINQRLADCSCDNELKNLIVRSAGTLFDEMPVFERLYISGTEYLVEQPEFQQPEKVRDLITMLEDKFSVATLVEQHHANNPDVTITIGKEHGKRQAEDLTVLSAPYYVGDMVGTVGILGPKRMDYEHAVRILHYMAGSLSSTLSIQN
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: XPT_BACSU
Sequence: MEALKRKIEEEGVVLSDQVLKVDSFLNHQIDPLLMQRIGDEFASRFAKDGITKIVTIESSGIAPAVMTGLKLGVPVVFARKHKSLTLTDNLLTASVYSFTKQTESQIAVSGTHLSDQDHVLIIDDFLANGQAAHGLVSIVKQAGASIAGIGIVIEKSFQPGRDELVKLGYRVESLARIQSLEEGKVSFVQEVHS
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so that it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_BRUC2
Sequence: MTIILKPGSVPLETLEKIYREGLPVRIDPAFHAGIEKAAARIAEIAAGDAPVYGINTGFGKLASIRIAAGDVATLQRNLILSHCCGVGEPLSENIVRLIMALKLVSLGRGASGVRLEVITLIEAMLEKGVIPMIPEKGSVGASGDLAPLAHMTAAMIGEGEAFYRGERLSGAKALGKAGLKPVVLAAKEGLALINGTQTSTALALAGLFRAHRAVRTALITGALSTDAAMGSDAPFHEEIHQLRGHKGQIDAGRALRTLLEGSAIRRSHLEGDQRVQDPYCIRCQPRVDGACLDILRQAARTLEIEANAVTDNPLVLSDGRAVSGGNFHAEPVAFAADQIALAVCEIGAISQRRIALLVDPSLSFGLPAFLTRKPGLNSGLMIAEVTSAALMSENKQMAHPASVDSTPTSANQEDHVSMACHGARRLLQMTANLNAIIGIEALTGALGVELRKPLTTSAELAKVIAALRAKVVTLEEDRYMADDLKAAAELVADGTLSGVISAGILPDLEA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBE2_CANGA
Sequence: MQKISVASMLKPVRLHTVREEAVAGAEAKAKVGAKTGAKMGAKTGAKSGLEADTAAGETLDAGASSEVLQLHVPRSRSHSQSISKSNSVISGSSYSSAGRIIGVNSARRPSDNLMLQISAHSDGDSDDEAGGDTPSKAAETHANAVPKPVRPTSDNSIRSNDTALFSANPTDSSNGSASDSDYDEQHDTSMVSGKSATTMMSPSLALSIGSGMTRSDVITPNKYSNLDSGSLGIAETPKARYIFSNVNRNRSQSSIKSSENSSPLRFVDGPNQRRTLPGASNTYLHSNSTSAILPTSRAMTPSHRYRLRKEMRDVALKKSIKQKEKFYEEQDSNLDLKDDNVDASLIWNIPMASYSTSSFLNTTDSKHKDTNIKVTSPENNRVINNKIERQDRRFPQKNQVHSRSQPNLPRLQQRPMKRPVHQQQQPITCFEDIPATPIPGVSNVTDTEFIQDTIQNLSSVYLHSQEMKSRGQLEKRQSSTQYLPLNVKEMSDLGMEDLVLVSDKKLEAVSSSRPTYLPPKSTKEKQMHEHEISKYMKMASDEQIQRKISQTKHMEEDKANHERYAHLLQRGITRKSSLFDLRKISWKTAISDELRCSIYHTILESDAQLVSSKYLENFDYLNSILDQMDFPTDKESEIKQIIEKNITTKIGYSSVKDKELTLLLKLKSISKQGLMVGDAQLFHNFLNCKSFKTLKDIWEIANLIQLTCFNDTCKDKFDSRIIDPRGITARILHSPSFKAEMTSSIMNFNTWWNIMSRIDNNLFMWIMDIIVIENCQCFTNKQINKDQLRDKNWDYYVNKYVVVNYKILASLAASVLLDYHFGFNDLKHLERIDKKFCIPLYSEDTECNIINSSFIKKWHHQYKKY
What is the function of this protein?
With SBE22, is involved in cell wall integrity and polarity processes like bud growth.
What are the official names of this protein?
Protein SBE2.
What is the protein family that this protein belongs to?
Belongs to the SBE2 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: HXCBA_DANRE
Sequence: MFNSVNLGNFCSQTRKDRTSEFGDRTGCASNIYLPSCTYYVPEFSAVSSFLPQGPSRQITYPYSTNLSQVQPVRDVSYGLDPSSKWHHRSNYASCYSGEDLVHRDCLPPSTMTEMLMKNESVYSHHHQHHPNSSHPSTGFYTGVGKNNVLPQGFDRFFETAYCSTDNQSEHCLQKSEMNKLETSSQQPTAVSAAREPEKDPEDEEEHTNSGSCTSAATKDGNASKSSHSSTPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C11a.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGB_YERPE
Sequence: MSVLPDRQVINQLISGHYGDPFSILGMHETSQGLQICALLPDAREVWLVETENGRRIAQLTLEDPRGFFIAQLTRRKKSFRYQFAVTWQENPQIIEDPYRFGPLLQDIDSWLLAEGTHLRPYERLGAHLMSLDGVSGVSFAVWAPNAQRVSVVGDFNFWDGRRHPMRLRRENGIWELFLPGIEAGQLYKFEIIDCHGQVRLKADPYAFEAQMRPETASLISPLPDVVKSSAARQKANDLCSPVSIYEVHLGSWRRHTDNNFWLSYRELADQLVEYVKYMGFTHVELLPINEHPFDGSWGYQPLGLYAPTRRYGTPEDFKAFVAKFHQAGINVILDWVPGHFPSDEHGLSTFDGTALYEYADPREGYHQDWNTLIYNYGRNEVRNYLAGNAFYWMERFGIDALRIDAVASMIYRDYSRAEGQWVPNYYGGRENLEAIAFLRYTNKTIGVERPGSVTMAEESTDFPGVTLPPDIGGLGFNYKWNMGWMHDTLNYMQCDPVHRKYHHNLMTFGMLYAYTENFILPLSHDEVVHGKRSILDRMPGDAWQKFANLRAYYAFMWAHPGKKLLFMGCEFAQGREWNFETSLDWHLLDDENGWHSGVQRLVRDLNHCYRQYAPLYEWDYQPAGFEWLVVDDHENSVFAFLRRDAEGHELIAISNFTPVPRYHYRVGIPQGGHYREVLNSDSAFYCGSNLGNQGGIDSHHVRSHNHEHSLLLTLPPLATIYLLREN
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RF3_ECOHS
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVSRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHSY_PERAE
Sequence: MVNVEAIRKVQRAEGPATIMAIGTSTPPNAVDQSEYPDYYYFGSPTASTRPSSRRSFKRMCEKSMIKKRYMYLTETYWKRIQMFVPTWLLPLKARQDMVVVEVPKLGKEVQPKAIKGMGQPKSKINPLVFCTTSGVDMPGADYQLTKVFGLPPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAALIVGADPVPGVENPMFELVSAGQTILPDSDGAIDGHLREVGLTFHLLKVVPGLISKNIEKSLVEAFEPLGISDWNSLFWIAHPGGPAILDPGGDQTRPEARESCGNQACFSVSMATCQVFVCSSFSTRCEGSPKEEGLKTTGEGIEWGVLFGFGPGLTVETVVLHSLPTH
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase, Naregenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: YD491_YEAST
Sequence: MEALVALQQTLSWFLLLVVVILIFFLLLSCLTQLRRLITKRMTKMENNRKVRNQNHFCKVNIALAELLTVSTDDTDMPLEKKSNSINRRVPTCTYIYMCACVYMSDIYMSNRLSKVFTLIAASIGREYCQIADALQAKKPLKNRWENGLARLSDLRAWTLKVA
What are the official names of this protein?
Putative uncharacterized protein YDR491C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RNH2_SULSY
Sequence: MDNVEKELFSQGYEKIVGIDEAGRGPLAGPLVIASVIFPKHQKPFIHTDSKGLSEKEREYLFEKIHDYAEEINITIVENTEIDKFGISNAAKIYMENNLKSLKSKWDIALVDFVKLDESINHLPLIKGDEISHTIAAASIIAKVVRDRIMIEYKEKYPNFSFDKHKGYATKQHYQEIKKFGITPIHRRSFNLGVNDD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMKL_ALTMD
Sequence: MNTILVTTSRGLDELLKQEVLTLCPDAQIKQGPGTIQFEGSKEDAYKLCLWSRLANRVIWVLASGKAGDAEALYNTAMGIDWQMQMDSRHTLSVQFIGTNFAIKNTQFGAVRVKDAIVDSFVEQGLPRPSVERKTPDISVYARLHRDNVILGIDLAGASLHQRAYRQETGDAPLKEHIASAMLMRSGWTENTDAPLVDLMCGSGTIAIEAAYIARNIAPGIKRSYWGFTKWLGHEATLWDSLLEDAISVQKPSCGGGIYAGDFSRKMVAIAKANADFAGVFNDISFSQQDATKSSPPVATPGYVVSNPPYGERLGELTSLIPLFSDWGKRFKEAWKGWHVSLLSSNRDLLRVLKLRATKDYAMNNGKLECRLANYVLDEQNTVQFSEDAGNHEFANRLKKNLKRMKGWVKSANTNCYRIYDADLPDYNVAVDRYGDWLVVQEYAPPKTVSEDKARKRLQEVLLHLPAVTGVSPKNIALKVRAQQKGSKQYEKINQSGEMMEVFENGARFLVNLTDYLDTGLFLDHRNTRQKVKALSQGKDVLNLFSYTGSVSVFAAMGGAKSVTTVDMSNTYLDWAKKNVALNKLSGPHAFIQADCTTWLGTHKGKYDLIFIDPPSFSNSKRMQNTWDVQRDHVKMLTDAKACLKEQGTIIFSNNKRGFKLDETAVTALGLQVENITKETIPEDFARKGKIHQCWVLRS
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAP1_YEAS8
Sequence: MSNTPYNSSVPSIASMTQSSVSRSPNMHTATTPGANTSSNSPPLHMSSDSSKIKRKRNRIPLSCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNELKKLRERVKSLEKTLSKVHSSPSSNSLKSYNTPESSNLFMGSDEHTTLVNANTGSASSASHMHQQQQQQQQQEQQQDFSRSANANANSSSLSISNKYDNDELDLTKDFDLLHIKSNGTIHLGATHWLSIMKGDPYLKLLWGHIFAMREKLNEWYYQKNSYSKLKSSKCPINHAQAPPSAAAAATRKCPVDHSAFSSGMVAPKEETPLPRKCPVDHTMFSSGMIPPREDTSSQKRCPVDHTMYSAGMMPPKDETPSPFSTKAMIDHNKHTMNPPQSKCPVDHRNYMKDYPSDMANSSSNPASRCPIDHSSMKNTAALPASTHNTIPHHQPQSGSHARSHPAQNRKHDSYMTESEVLATLCEMLPPKRVIALFIEKFFKHLYPAIPILDEQNFKNHVNQMLSLSSMNPTVNNFGMSMPSSSTLENQPITQINLPKLSDSCNLGILIIILRLTWLSIPSNSCEVDLGEESGSFLVPNESSNMSASALTSMAKEESLLLKHETPVEALELCQKYLIKFDELSSISNNNVNLTTVQFAIFYNFYMKSASNDLTTLTNTNNTGMANPGHDSESHQILLSNITQMAFSCGLHRDPDNFPQLNATIPATSQDVSNNGSKKANPSTNPTLNNNMSAATTNSSSRSGSADSRSGSNPVNKKENQVSIERFKHTWRKIWYYIVSMDVNQSLSLGSPRLLRNLRDFSDTKLPSASRIDYVRDIKELIIVKNFTLFFQIDLCIIAVLNHILNVSLARSVRKFELDSLINLLKNLTYGTENVNDVVSSLINKGLLPTSEGGSVDSNNDEIYGLPKLPDILNHGQHNQNLYADGRNTSSSDIDKKLDLPHESTTRALFFSKHMTIRMLLYLLNYILFTHYEPMGSEDPGTNILAKEYAQEALNFAMDGYRNCMIFFNNIRNTNSLFDYMNVILSYPCLDIGHRSLQFIVCLILRAKCGPLTGMRESSIITNGTSSGFNSSVEDEDVKVKQESSDEMKKDDFMKDVNLDSGDSLAEILMSRMLLFQKLTKQLSKKYNYAIRMNKSTGFFVSLLDTPSKKSDSKSGGSSFMLGNWKHPKVSNMSGFLAGDKDQLQKCPVYQDALGFVSPTGANEGSAPMQGMSLQGSTARMGGTQLPPIRSYKPITYTSSNLRRMNETGEAEAKRRRFNDGYIDNNSNNDIPRGISPKPSNGLSSVQPLLSSFSMNQLNGGTIPTVPSLTNITSQMGALPSLDRITTNQINLPDPSRDEAFDNSIKQMTPMTSAFMNANTTIPSSTLNGNMNMNGAGTANTDTSVNGSALSTLTSPQGSDLASNSATQYKPDLEDFLMQNSNFNGLMINPSSLVEVVGGYNDPNNLGRNDAVDFLPVDNVEIDGLVDFYRADFPIWE
What is the function of this protein?
Regulation of oxygen dependent gene expression.  It modulates the expression of Iso-1 (CYP1) and Iso-2 (CYP3) cytochrome c.  In response to heme, promotes transcription of genes encoding functions required for respiration, controlling oxidative damage and repression of anaerobic genes.  Binds to the sequence 5'-CGGNNNTNNCGG-3' (By similarity).
What are the official names of this protein?
Heme-responsive zinc finger transcription factor HAP1, CYP1 activatory protein, Heme activator protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL10_HERAR
Sequence: MSLNLNDKKAVVAEISAKVATAQTIVVAEYRGIQVGHLTQLRAKARDQGVYLRVLKNTLARRAVEGTAFADLASEMTGPLIYSISDDAVAAAKVISDFAKTNDKLVVKAGNYAGKTLDKAAVTALANIPSREVLLAQVLGMMLVPVASFTRGLAALAAKKAEGETPAAAAEPVAEVTEAAAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ZNF22_MOUSE
Sequence: MRLGKPKGGISRSASQGKAYESKRKTARQRQKWGVAIRFDSGLSRRRRNVDEKPYKCAKCSKSFSQSSTLFQHKKIHTGKKSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDECGERFKQSSNLIQHQRIHTGEKPYCCDECGRCFSQSSHLIQHQRTHTGEKPYQCEECDKCFSQSSHLRQHMKVHKEKKPHKRGKNARVKTHPVSWKRGKGRKAVAGIRQVKGATSGLFKKKK
What is the function of this protein?
Binds DNA through the consensus sequence 5'-CAATG-3'.  May be involved in transcriptional regulation and may play a role in tooth formation.
What are the official names of this protein?
Zinc finger protein 22, Zinc finger protein 422, Zinc finger protein Krox-25, Zinc finger protein Krox-26.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAPP_STRCO
Sequence: MSSADDQTTTTTSSELRADIRRLGDLLGETLVRQEGPELLELVEKVRRLTREDGEAAAELLRGTELETAAKLVRAFSTYFHLANVTEQVHRGRELGAKRAAEGGLLARTADRLKDADPEHLRETVRNLNVRPVFTAHPTEAARRSVLNKLRRIAALLDTPVNESDRRRLDTRLAENIDLVWQTDELRVVRPEPADEARNAIYYLDELHLGAVGDVLEDLTAELERAGVKLPDDTRPLTFGTWIGGDRDGNPNVTPQVTWDVLILQHEHGINDALEMIDELRGFLSNSIRYAGATEELLASLQADLERLPEISPRYKRLNAEEPYRLKATCIRQKLENTKQRLAKGTPHEDGRDYLGTAQLIDDLRIVQTSLREHRGGLFADGRLARTIRTLAAFGLQLATMDVREHADAHHHALGQLFDRLGEESWRYADMPREYRTKLLAKELRSRRPLAPSPAPVDAPGEKTLGVFQTVRRALEVFGPEVIESYIISMCQGADDVFAAAVLAREAGLIDLHAGWAKIGIVPLLETTDELKAADTILEDLLADPSYRRLVALRGDVQEVMLGYSDSSKFGGITTSQWEIHRAQRRLRDVAHRYGVRLRLFHGRGGTVGRGGGPTHDAILAQPWGTLEGEIKVTEQGEVISDKYLIPALARENLELTVAATLQASALHTAPRQSDEALARWDAAMDVVSDAAHTAYRHLVEDPDLPTYFLASTPVDQLADLHLGSRPSRRPGSGVSLDGLRAIPWVFGWTQSRQIVPGWYGVGSGLKALREAGLDTVLDEMHQQWHFFRNFISNVEMTLAKTDLRIAQHYVDTLVPDELKHVFDTIKAEHELTVAEVLRVTGESELLDADPVLKQTFTIRDAYLDPISYLQVALLGRQREAAAANEDPDPLLARALLLTVNGVAAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: CHSY_ANTMA
Sequence: MVTVEEVRRAQRAEGPATVLAIGTATPANCVDQSTYPDYYFRITNSEHMTELKEKFKRMCDKSNIKRRYMHLTEEILKENPAMCEYMAPSLDARQDIVVVEVPRLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAVTFRGPADTHLDSLVGQALFGDGAAAVIVGSDPVVGVERPLFQIVTAAQTLLPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFDPLGISDWNSVFWIAHPGGPAILDQVEEKLGLKPEKLRSTRQVLSEYGNMSSACVLFILDEMRKSSAKEGMSTTGEGLDWGVLFGFGPGLTVETVVLHSVPLN
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase, Naringenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: AROB_STRP3
Sequence: MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQTVYHLYQTLFEEFAQQYNAFVHVYPSGGQSKSLERVSAIYDQLIAENFSKKDMIVTIGGGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPEAIIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLERLIYQSISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAVSKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTETGFTTLAINKDDHQFVEKLDSLL
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPDF_BART1
Sequence: MSISIAAIILAAGRGERAGSPHKIPKQYRLLGKKPIIYHTVCRFLRHPAITTIILVIHPEDRQICEQALAEFKERFIIVEGGSTRQISTLHGLQALKKFNPQYVHIHDGARPFIENELLDNIHNTLTPQEGVLPVLPISDTLKRVNHQYVLETIPRTHLYSAQTPQCFPFEPILAAHKQAKRVCKEDFTDDCAIAEWFGLPMRTIPGDPHNIKITWHKDFDTAHLYLQKKMQMFPDIRVGNGYDVHSFEEGDFLILCGIRIPFHKKLNGHSDADVALHALTDALLATRGAGDIGTHFPPSDPQWKNVSSEIFLRHALSLLKQAGGRIANVDITVIAENPKIGPYRHAMIENLMTILAITPDRISIKATTNERLGFIGRGEGIAALATASVLYPGEIPQ
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: AMPA_BORPA
Sequence: MEFSTQTTASLHQIKTAALAVGVFADGVLSAAAEVIDRASHGAVAAVVKSEFRGRTGGTLVLRSLAGVSAQRVVLVGLGKQAEYNARAHASAEQAFAAACVAAQVGEGVSTLAGVAIEGVPVRARARSAAIAAGAAAYHYDATFGKANRDARPRLKKIVQVVDRAASAQTQLGLREGAAIAHGMELTRTLGNLPGNVCTPAYLGNTAKKLAREFKSLKVEVLERKQVEALGMGSFLSVARGSEEPLRFIVLRHAGKPAKKDKAGPVVLVGKGITFDAGGISLKPAATMDEMKYDMCGAASVLGTFRALAELELPLDVVGLIAACENLPSGKANKPGDVVTSMSGQTIEILNTDAEGRLVLCDALTYAERFKPAAVIDIATLTGACVVALGNVNSGLFSKDDALADALLAASRQSLDPAWRLPLDDAYQDQLKSNFADIANIGGPPAGAVTAACFLSRFTKAYPWAHLDIAGTAWRGGKDKGATGRPVPLLMQYLLDQAG
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.