PharMolix/UniProtQA huggingface dataset:
Protein: PG094_VACCC
Sequence: MGGGVSVELPKRDPPPGVPTDEMLLNVDKMHDVIAPAKLLEYVHIGPLAKDKEDKVKKRYPEFRLVNTGPGGLSALLRQSYNGTAPNCCRTFNRTHYWKKDGKISDKYEEGAVLESCWPDVHDTGKCDVDLFDWCQGDTFDRNICHQWIGSAFNRSNRTVEGQQSLINLYNKMQTLCSKDASVPICESFLHHLRAHNTEDSKEMIDYILRQQSADFKQKYMRCSYPTRDKLEESLKYAEPRECWDPECSNANVNFLLTRNYNNLGLCNIVRCNTSVNNLQMDKTSSLRLSCGLSNSDRFSTVPVNRAKVVQHNIKHSFDLKLHLISLLSLLVIWILIVAI
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex protein OPG094, EFC protein OPG094, Myristoylated protein G9.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG086 family.
Protein: ABCI_ASPFU
Sequence: MDEKPAVSESSNGSDVDSLSTASAYEQHRERLRDANPQGVTSHRSGVNVKEAEEEFSELNRQFSTISHQAHCLSKQISRASKPTGKTEDVERSDSPADSDEPWDLETALRGNRDAETAAGIRSKRIGVIWDNLTVRGMGGVKTYIKTFPDAIIDFFNVPETIMHMLGYGKKGKEFEILRNFRGVLQPGEMVLVLGRPGSGCTTFLKTITNQRFGYTSIDGDVLYGIFDADTFAKRFRGEAVYNQEDDVHQPTLTVKQTLGFALDTKTPGKRPLGVSKAEFREKVINMLLKMFNIEHTANTVIGNQFIRGVSGGERRRVSIAEMMITSATVLAWDNSTRGLDASTALDFAKSLRIMTNIYKTTTFVSLYQASENIYKQFDKVLVIDSGRQVFFGPASEARSYFESLGFKERPRQTTPDYLTGCTDPFEREFKEGRSEDDVPSTPDSLVEAFNRSSYSERLAQEMDAYRKKLEQEKHVYEDFEIANQEAKRKFTPKSSVYSIPFHLQIWALMQRQFLIKWQDRFAQTVSWITSTGVAIILGTVWLRLPKTSAGAFTRGGLLFISLLFNGFQAFSELVSTMMGRSIVNKHRQFTFYRPSALWIAQILVDTTFAIARILVFSIIVYFMCGLVLDAGAFFTFILIIVLGYLCMTCFFRVIGCMSPDFDYAMKFASVVITLFVLTSGYLIQWSSEQEWLRWLYYINPFGLGFAALMVNEFKDLTMTCTADSLVPSGPGYDDMASRVCTLAGGEPGSVIIPGASYLAKTFSYFPGDLWRNFGIMVALTVGFLTLNLYHGETLQFGAGGRTVTFYQKENKERRALNGALMEKRTNRESKDQSAANLKITSKSVFTWEDVCYDVPVPSGTRRLLQSVYGYVQPGKLTALMGASGAGKTTLLDVLASRKNIGVISGNILVDGAPPPGSFLRTVSYAEQLDIHEPMQTVREALRFSADLRQPYETPQSEKYEYVEGIIQLLELEDLADAIIGTPETGLSVEERKRVTIGVELAAKPELLLFLDEPTSGLDSQSAFNIIRFLRKLAAAGQAILCTIHQPNSALFENFDRLLLLQRGGECVYFGDIGEDSHVLLDYFRRNGADCPPDANPAEWMLDAIGAGQTRRIGDRDWGEIWRTSSEFEQVKREIIQIKAQRAEEVRQSGGSQIIVREYATPLWHQIKVVCKRTNIVFWRSRNYGFTRLFNHVVIALVTGLAFLNLDDSRASLQYRIFVIFNVTVLPAIILQQVEPRFEFSRLVFFRESACKSYSQFAFALSMVIAELPYSILCAVCFFLPLYYIPGFQAAPSRAGYQFLMVLITELFSVTLGQMISALTPNSFIASQINPPIVIIFSLFCGVAIPRPQMPGFWRAWLYQLDPFTRLISGMVTTELHGRTVSCSPSEFNRFQAPENQTCGEYMLPFFERGGLGYLADNTTQACEYCAYKIGDEFYSAFSMSFNTRWRDLGIFLAFIGSNLIILFLAVSFMSPRCRLRYKLIYDIF
What is the function of this protein?
ABC efflux transporter that confers resistance to fluconazole (FLC) but shows no resistance to other azoles (PubMed:32209680).  Is also able to transport rhodamine 6G (R-6G), a known substrate for many ABC transporters (PubMed:32209680).
What are the official names of this protein?
ABC multidrug transporter I.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABA_ECO81
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTANDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTC_YERPY
Sequence: MKFFALFIQRPVATTLLTLAITLSGIIGFSLLPVSPLPQVDYPVIMVSASMPGADPETMASSVATPLERALGRIAGVNEMTSTSSLGSTRIILQFDLNRDINGAARDVQAALNAAQSLLPSGMPSRPTYRKMNPSDAPIMIMTLTSDTFSQGQLYDYASTKLAQKIAQTEGVSDVTVGGSSLPAVRVELNPSALFNQGVSLDAVRQAISAANVRRPQGSVDAAETHWQVQANDEIKTAEGYRPLIVHYNNGSPVRLQDVANVIDSVQDVRNAGMSAGQPAVLLVISREPGANIIATVDRIRAELPALRASIPASIQLNIAQDRSPTIRASLDEVERSLVIAVALVILVVFIFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVKPMVAALRGVREVGFTVLSMSISLVAVFIPLLLMAGLPGRLFREFAVTLSVAIGISLVISLTLTPMMCAWLLRSHPKGQQQRIRGFGKVLLAIQQGYGRSLNWALSHTRWVMVVLLSTIALNVWLYISIPKTFFPEQDTGRMMGFIQADQSISFQSMQQKLKDFMQIVGADPAVDSVTGFTGGSRTNSGSMFISLKPLSERQETAQQVITRLRGKLAKEPGANLFLSSVQDIRVGGRHSNAAYQFTLLADDLAALREWEPKVRAALAKLPQLADVNSDQQDKGAEMALTYDRETMARLGIDVSEANALLNNAFGQRQISTIYQPLNQYKVVMEVAPEYTQDVSSLDKMFVINSNGQSIPLSYFAKWQPANAPLAVNHQGLSAASTISFNLPDGGSLSEATAAVERAMTELGVPSTVRGAFAGTAQVFQETLKSQLWLIMAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNISAREAIFQASLLRFRPIIMTTLAALFGALPLVLSSGDGAELRQPLGITIVGGLVVSQLLTLYTTPVIYLYFDRLRNRFSKQPLMKLE
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEN2_MOUSE
Sequence: MMLSPDQAADSDHPSSTHSDPESLGGADTKVLGSVSDLEPVEEADGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
What is the function of this protein?
Transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3' (PubMed:15470499, PubMed:18356286).  Involved in regulating energy expenditure, body mass, voluntary physical activity, mating behavior and reproductive longevity, acting through the hypothalamic-pituitary-gonadal axis (PubMed:15470499, PubMed:12419415, PubMed:9090387, PubMed:17717072, PubMed:23785158, PubMed:15465527).  Acts as a transcriptional activator of target genes, including Ndn, Pcsk1, Mc4r (PubMed:15470499, PubMed:18356286, PubMed:21664420).  Is also a transcriptional activator of KISS1 (By similarity).  May act centrally to regulate function of both white and brown adipose tissue (PubMed:20808804, PubMed:19436734).  Together with NHLH1, required to maintain migration and survival of cells in the anterior extramural migration stream (aes), which forms the precerebellar nuclei (PubMed:17573818).  Also, in concert with Nhlh1, may determine fate of gonadotropin releasing hormone-1 (GnRH-1) neurons (PubMed:15470499).
What are the official names of this protein?
Helix-loop-helix protein 2, HEN-2, Nescient helix loop helix 2, NSCL-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRDR_THIDA
Sequence: MKCPFCGSLDTQVIDSRANEAGDAIRRRRRCAACDKRFTTWETAELRPPQIVKTNGTREDFSETKLREGFRRALHKRPVSTELVDAAVDRIRQRLLTLGEREVPAREVGELVMTELKKLDKIAYIRFASVYKSFKDPDDFRDVLEDLAQGPQAGDDPA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: STX5_DROME
Sequence: MQTRRRLHQTDQQDYSSSSTYTIQEDQQGGAGAGSVGTGTAGGSVGLLAQSLVPPPTGHEAAIHIGDNYQSGDSISTPDYSDDKYGKAARQWNLRAFSGHALRTLSAAAAVVTGNQPGINNDSQSNYSYPASIPTSSQFYQSKEEPQETEPEPEIFVMAARDRTGEFANAIRSLQARNITRAVNIRDPRKAKQVQSYSEFMMVARFIGKNIASTYAKLEKLTMLAKKKSLFDDRPQEIQELTYIIKGDLNALNQQIARLQDISKDQRRHTNGKHLVSHSSNMVLALQSKLASMSTDFKQILEVRTENLKQQKTRRDQFSQGPGPLAAHTVSPSTAKQGSLLLSEENQAVSIDMGSSDTTPLLSTQTQMAIYDDSDNYVQQRAETMQNIESTIVELGGIFQQLAHMVKEQEEIVERIDTNVADAELNIEAAHGEILKYFQSVSKNRWLMIKIFGVLIFFFLFFVVFMS
What is the function of this protein?
Mediates endoplasmic reticulum to Golgi transport.
What are the official names of this protein?
Syntaxin-5, Sed5 protein, dSed5.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein.
Protein: FEOC_SALDC
Sequence: MASLIQVRDLLALRGRMEATQISHTLHAPQPMIDAMLNQLEIMGKAVRIPEEADGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: SODM_CUPMC
Sequence: MLYEMKPLGCEPAKLTGLSEKLIFSHYENNYGGAVKRLNAITATLAELDMATAPVFTLNGLKREELIATNSMILHEVYFDSLGDGGSLDGALKTAIERDFGSVERWQAEFTAMGKALGGGSGWVLLTYSPRDGRLVNQWASDHAHTLAGGTPVLALDMYEHSYHMDYGAKAAAYVDAFMQNIHWQRAATRFAAAVRD
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: GATC_BACC3
Sequence: MSRISVENVKHVAHLARLAITDQEAEKFQKQLDAIVTFAEQLNELDTTDVKPTTHVLTMKNVMREDVPEKGLPVEEVLKNAPDHKDNQIRVPAVLE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: Y231_STRP3
Sequence: MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELNTALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSNVNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDDVEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKLIDALESDDDVQKVYHNVADF
What are the official names of this protein?
Probable transcriptional regulatory protein SpyM3_0231.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_THEGJ
Sequence: MIDKVYCADVKPEMEGKRVKLAGWVYRKREVGKKVFIVLRDSSGIVQVVFSKELNEEAYREAKKLGIESSVIIEGTVKADPRAPTGAEVQADKLQVIQNVDFFPITKDASPEFLLDVRHLHLRSPKVASIMKVKGTLMQAAREWLLQDGWYEVFPPILVTGAVEGGSTLFKLKYFDKTAYLSQSAQLYLEAAIFGLEKVWSLTPSFRAEKSRTRRHLTEFWHLELEAAWMDLWDIMKVEEELVSYMVQRTLELRRSEIETFRKDLTTLKNAVPPFPRISYDEAIDILQSKGVEIEWGEDMGADEERVLTEEFEAPFFVYGYPKHIKAFYMKEDPEDPRKVLAADMLAPEGYGEIIGGSQREDNYDKLIQRILEEGMDPKDYEWYLDLRKYGSVPHSGFGLGLERLVAWVLKLDHVRWATLFPRTPSRLYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_ZYMMO
Sequence: MTEKVKRVVLAYSGGLDTSVILKWLQEHYGCEVVTFTADLGQGEELEPARKKAEMMGIKPEHIFMDDLREEFVRDFVFPMMRANALYEGQYLLGTSIARPLIAKRQIEIARQVGADAVAHGATGKGNDQIRFELGYYALAPDIKVIAPWREWDLNSRSKLIAYAESRQIAVPKDKRGESPFSVDSNLLHTSSEGKILEDPWQEVPDYVYSRTVNPEDAPNTPEIITIDFERGDAIAINGEALSPAELLTKLNELGRKHGIGRLDLVENRYIGMKSRGMYETPGGTILIQAHRGIEQLTLDGGAMHLKDELMPRYAELIYNGFWYSPEREMLQAAIDHSQARVSGTVRLKLYKGSVNVIGRKSPNSLYSEKVVTFEDDAGAYNQQDAAGFIKLNALRLRLLGERNAKGL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AB12C_ARATH
Sequence: MGFEALNWYCKPVADGFWEKAVDGAFGAYTPCAIDSLVMLVSHFVLLGLCFYRIWIIFHNTKAQIYVLRKKYYNCVLGLLACYCVVEPVLRLVMGISLFDMDEETDFPPFEVASLMVEAFAWFSMLVLIGLETKQYVKEFRWYVRFGVLYVLVADAVLLDLVLPLKNSINRTALYLFISSRCSQALFGILLLIYIPELDPYPGYHIVNNEPLDNVEYDALRGGEHICPERHASIFSRIYFGWITPLMQLGYRKPITEKDVWQLDKWDQTETLIKRFQRCWTEESRRPKPWLLRALNNSLGGRFWLAGIFKIGNDLSQFVGPVILSHLLRSMQEGDPAWVGYVYAFIIFVGVTLGVLCEAQYFQNVWRVGFRLRSTLVAAIFHKSLRLTHEARKNFASGKVTNMITTDANALQQISQQLHGLWSAPFRIIVSMILLYQQLGVASLFGSLILFLLIPLQTLIISKMRKLTKEGLQWTDKRVGITNEILSSMDTVKCYAWEKSFESRIQGIRNEELSWFRKAQLLSAFNSFILNSIPVVVTVVSFGVFVLLGGDLTPARAFTSLSLFAVLRFPLNMLPNLLSQVVNANVSLQRIEELLLSEERILAQNPPLQPGTPAISIKNGYFSWDSKTTKPTLSDINLEIPVGTLVAIVGGTGEGKTSLISAMLGELSHAETTSVVIRGSVAYVPQVSWIFNATVRENILFGSDFESERYWRAIDATALQHDLDLLPGRDLTEIGERGVNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVAHQVFDSCMKDELRGKTRVLVTNQLHFLPLMDKIILVSEGMIKEEGTFVELSKSGILFKKLMENAGKMDATQEVNTNDENILKLGPTVTVDVSERNLGSTKQGKRRRSVLIKQEERETGIISWNVLMRYKEAVGGLWVVMILLACYLATEVLRVSSSTWLSIWTDQSTSKNYSPGFYIVVYALLGFGQVAVTFTNSFWLITSSLHAARRLHDAMLSSILRAPMLFFHTNPTGRVINRFSKDIGDIDRNVANLMNMFMNQLWQLLSTFALIGTVSTISLWAIMPLLILFYAAYLYYQSTSREVRRLDSVTRSPIYAQFGEALNGLSSIRAYKAYDRMAKINGKSMDNNIRFTLANTSSNRWLTIRLETLGGVMIWLTATFAVLQNGNTNNQAGFASTMGLLLSYTLNITSLLSGVLRQASRAENSLNSVERVGNYIDLPSEATDIIENNRPVCGWPSGGSIKFEDVHLRYRPGLPPVLHGLTFFVSPSEKVGVVGRTGAGKSSMLNALFRIVEVEKGRIMIDDCDVAKFGLTDVRRVLSIIPQSPVLFSGTVRFNIDPFSEHNDAGLWEALHRAHIKDVISRNPFGLDAEVCEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRTDSLIQRTIREEFKSCTMLVIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAFFRMVHSTGPANAQYLSNLVFERRENGMSVGG
What is the function of this protein?
Pump for glutathione S-conjugates.
What are the official names of this protein?
ABC transporter C family member 12, ABC transporter ABCC.12, AtABCC12, ATP-energized glutathione S-conjugate pump 13, Glutathione S-conjugate-transporting ATPase 13, Multidrug resistance-associated protein 13.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PURT_XANOR
Sequence: MTTLGTPLSPSATRVLLLGSGELGKEVAIELQRFGVEVIAADRYANAPAMQVAHRSHVLDMLDPAALRVLIASERPHVIVPEIEAIHTETLVALEREQGQKVIPAARAARLTMDREGIRRLAAETLGLPTSPYRFVDTAADYREAIAAVGLPCVVKPVMSSSGKGQSTLRSEADIDAAWEYAQTGGRAGAGRCIVEGFIDFDYEITLLTVRHAGGTSYCDPIGHWQQDGDYRESWQPQPMSAAALRRSQEIAKAITDDLGGWGLFGVELFVKGDEVWFSEVSPRPHDTGLVTLVSQELSEFALHARAILGLPVGAEDGGVIGQSGPSASCALLAHGNGVPVFDNVADALRDPNTALRLFGKPRVDGHRRVGVTLARADSIDAAREKARVAAAALGIQLTA
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RS12_METFK
Sequence: MPTINQLVRKPRQKVVAKSKVPALESCPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGYEVISYIGGEGHNLQEHSVVLLRGGRVKDLPGVRYHMVRGSLDTAGVKDRKQARSKYGAKRPKAA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL1_BACHK
Sequence: MAKRGKKYVEAAKLVDRAAAYSATEAVELVKKTNTAKFDATVEAAFRLGVDPKKADQQIRGAVVLPHGTGKVQRVLVFAKGEKAKEAEAAGADFVGDADYIGKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTFDVTKAVNEIKAGKVEYRVDKAGNIHVPIGKVSFEDAKLVENFRTIADTLQKVKPAAAKGTYMKNVTVASTMGPGVRVDVSTLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: COAD_ALIF1
Sequence: MTKLTLYPGTFDPITNGHLDLIKRSASMFDHIIVAVAASPSKKTLFTLDERVQLVQAVTKDLPNVYVEGFSGLMVDFAKEKKANLLVRGLRTTMDFEYEFGLTSMYRKLMPELESVFLTPSEEYAFLSSTIVREVALHGGSVEAFVPSSVNQALKNKVASSL
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOCS4_BOVIN
Sequence: MAENSESNSKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSESCSDAETVSAIEKTEVPLRSQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQCFPIKNCSSRHSSGLPSKRKIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPISPKSDEWVSTDLSQSELRDGQLKQRRNMEEVSCFSHTSVQPCVITSNNSSGRGGPGTDSIVNLASNNSIEDSDMDSDDEIITLCTSSRKRNKPKWEIDEEILQLETPPKYHTQIDYVHCLVPDLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQHICRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC
What is the function of this protein?
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction.  Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR (By similarity).
What are the official names of this protein?
Suppressor of cytokine signaling 4, SOCS-4.
Protein: RL5_PSEPK
Sequence: MARLKEIYRNEIAPKLKEELKLSNVMEVPRVTKITLNMGLGEAIGDKKVIEHAVADLEKITGQKPVVTFARKSIAGFKVREGWPIGVKVTLRSDKMYEFLDRLLAISLPRVRDFRGLNAKSFDGRGNYSMGVKEQIIFPEIDYDKIDALRGLDITLTTTARSDDEGRALLRAFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: LIPB_THEFY
Sequence: MKSVSELLYHWLGESPVPYMEGWELQRQLHKRRVADQVPDTVLLLEHEPVYTAGKRTGPWDRPLTDPGAPVIDIDRGGKITWHGPGQLTAYPIVKLPAPLDVVAYVRMLEEAIIRVIGDFGLSGMRVEGRTGVWLAAAPDRGLPERKIAAIGCRIAKGVTMHGFALNCNNDLSWFDRIVPCGIRDAGVTSLTAELDRTVGVGDILEATEHHLAAVLGASSYRRIAGWPVLPEFVDA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y058_ARCFU
Sequence: MAFRQPNTKELKVIRKALSYYGSGDFLSHYALLVKEGEKKEVYGVSKELYGVIGELNPHYAGVKIGEVGRRFRFSLEGTFWLLRNSRNRVWVNERGEMLFLYGRDIFAGSVERASEFGENSIVFVCNRFDDVLGIGRSRHSSDELSNLPEDKVFVENLVDRGEYLRHQKTYLSF
What are the official names of this protein?
UPF0113 protein AF_0058.
What is the protein family that this protein belongs to?
Belongs to the UPF0113 family.
Protein: RL28_WOLPM
Sequence: MSRVCELTNRKKSFGNKVSHSNRKTKRTFLLNLHKVTLTSDILNKKFRFRVATRTLRTIDYKGDLDAFLLNTRTIKLSEKAQKIKRRLKKVLVKQEVELAVSDA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: H33A_DROME
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes and is specifically enriched in modifications associated with active chromatin.  Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis.  Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3A, H3.A.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RHO1_YEAST
Sequence: MSQQVGNSIRRKLVIVGDGACGKTCLLIVFSKGQFPEVYVPTVFENYVADVEVDGRRVELALWDTAGQEDYDRLRPLSYPDSNVVLICFSIDLPDSLENVQEKWIAEVLHFCQGVPIILVGCKVDLRNDPQTIEQLRQEGQQPVTSQEGQSVADQIGATGYYECSAKTGYGVREVFEAATRASLMGKSKTNGKAKKNTTEKKKKKCVLL
What is the function of this protein?
Acts as a central regulator in the cell wall integrity signaling pathway, which is regulated by the cell cycle and in response to various types of cell wall stress.  Integrates signals from different cell surface sensors, and activates a set of effectors, regulating processes including beta-glucan synthesis at the site of wall remodeling, gene expression related to cell wall biogenesis, organization of the actin cytoskeleton, and protein- and secretory vesicle-targeting to the growth site.  Activates the protein kinase C (PKC1) MAP kinase cascade, the beta-1,3-glucan synthase (FKS1), the formin BNI1, the exocyst component SEC3 and the transcription factor SKN7.
What are the official names of this protein?
GTP-binding protein RHO1, Rho-type GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Endosome membrane; Lipid-anchor. Peroxisome membrane; Lipid-anchor. Note=Plasma membrane- associated at sites of polarized growth such as incipient bud sites, bud tips, the bud neck during cytokinesis, and the neck and tip of mating projections. Also found on internal membranes of endosomes and peroxisomes.