PharMolix/UniProtQA huggingface dataset:
Protein: CAF17_PHANO
Sequence: MASRILAAPVQRCRRSQHDRRPIAVSATHNGFSRLPTALRSYFTEASTAQAIASGIAPLPHRSLIFLSGPTASKFLHGLITHDATRVSPFYAAFLDARGRVICDVFIWVWPELIAQQGHWACYIEVDAGQANALMLHLKRHKLRHKLTISHVPAEGRDGIKVWAAWGDAHKQVKDWGEIAGLQDPRAPGMYRYLANADRETIARDMQPVDTKFYDIQRYIHGVPEGSAEMPPYSTLPMEANIDLSSGIDFKKGCYIGQELTIRTKHTGVVRKRILPVRFHAGGAGAADPQAPVNPSFAPQPQPGMDIRTLDDTGALSKGRPTGRIVAAIGNVGLATCRIENMTSMRVSTEGGFYKEGTQFGVDVDGQVVRVEPVVHDWFVERKEALWGRGEKMKKSWVEKAQEELD
What are the official names of this protein?
Putative transferase CAF17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GcvT family. CAF17 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GPX5_CHLRE
Sequence: MANPEFYGLSTTTLSGQPFPFKDLEGKAVLIVNVASKCGFTPQYKGLEELYQQYKDRGLVILGFPCNQFGGQEPGDASAIGEFCQRNFGVTFPIMEKSDVNGNDANPVFKYLKSQKKQFMMEMIKWNFEKFLVDKSGQVVARFSSMATPASLAPEIEKVLNA
What is the function of this protein?
Has thioredoxin peroxidase activity (PubMed:19690965).  May also have glutathione peroxidase activity, although this activity is controversial (PubMed:29124185).  Protects cells against reactive oxygen species, which may include photooxidative stress, hydrogen peroxide and organic hydroperoxides (Ref. 1, PubMed:19690965, PubMed:29124185, PubMed:32344528, PubMed:32599138).
What are the official names of this protein?
Glutathione peroxidase-like peroxiredoxin GPX5, CrGPX5, Glutathione peroxidase GPX5, Glutathione peroxidase homolog.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: SODC_DROSE
Sequence: MVVKAVCVINGDAKGTVFFEQESSGTPVKVSGEVCGLAKGLHGFHVHEFGDNTNGCMSSGPHFNPYGKEHGAPVDENRHLGDLGNIEATGDCPTKVNITDSKITLFGADSIIGRTVVVHADADDLGQGGHELSKSTGNAGARIGCGVIGIAKV
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn], Superoxide dismutase 1.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMX7_CAEEL
Sequence: MSFSAGESSAATGDPQDFNKFFGEINSPSEAAKTIKAIPKPSVALPESSECASYCASWVNDQSFEILPTDEENRQTEFSSSPLSDSVHSCLGFNRKKERKRRTSGDIEQTDKRKRTEERPSDKITFASNVFDNLARVTAERDNPEKLSKYKNIPGVGTRENIDEGISDINQPSSKSSGVKSKYVEVMSLFQKSIQKFSIMNLDYMYTFDWNHYSKKNIQYVVFTKVCQSHAPGHFVEMLKEDCSCRDCGSADLAVKVRLTVPLDLSDIPIPCSEDIQIHVSFLADDLLERHISSNVNRSSNRDDLDFSRRTCEKMYDLYQKMMRGQSSRMYTEWFDKCKIFVKNFLFSKSLHLYHGNVIRRKIEESQTLNKRRCFIFAQIFDLE
What are the official names of this protein?
Uncharacterized protein K06H7.7.
Protein: MVAA_PSEMV
Sequence: MSLDSRLPAFRNLSPAARLDHIGQLLGLSHDDVSLLANAGALPMDIANGMIENVIGTFELPYAVASNFQINGRDVLVPLVVEEPSIVAAASYMAKLARANGGFTTSSSAPLMHAQVQIVGIQDPLNARLSLLRRKDEIIELANRKDQLLNSLGGGCRDIEVHTFADTPRGPMLVAHLIVDVRDAMGANTVNTMAEAVAPLMEAITGGQVRLRILSNLADLRLARAQVRITPQQLETAEFSGEAVIEGILDAYAFAAVDPYRAATHNKGIMNGIDPLIVATGNDWRAVEAGAHAYACRSGHYGSLTTWEKDNNGHLVGTLEMPMPVGLVGGATKTHPLAQLSLRILGVKTAQALAEIAVAVGLAQNLGAMRALATEGIQRGHMALHARNIAVVAGARGDEVDWVARQLVEYHDVRADRAVALLKQKRGQ
What is the function of this protein?
P. mevalonii can use mevalonate as sole carbon source.  With this enzyme mevalonate is deacetylated to HMG-CoA.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
Protein: TGT_ECO45
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: GLNB_RHIME
Sequence: MKKIEAIIKPFKLDEVKEALQEVGLQGITVTEAKGFGRQKGHTELYRGAEYVVDFLPKVKVEVVLADENAEAVIEAIRNAAQTGRIGDGKIFVSNVEEVIRIRTGETGLDAI
What is the function of this protein?
In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP.  P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.  Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS.  P-II indirectly controls the transcription of the GS gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA.  When P-II is uridylylated to P-II-UMP, these events are reversed.
What are the official names of this protein?
Nitrogen regulatory protein P-II.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: VF111_ASFB7
Sequence: MSFSECPLVISACKKFLQKRITIENEALINALITALAQTSTLNDLCLLPIQTYLLSYKNAFEWIHFVCIAITTILDNKYNWKNCTVDINYIFLHVTYIYNIKTKEYLDYCS
What are the official names of this protein?
Uncharacterized protein E111R, pE111R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus E111R family.
Protein: YOD1_SCHPO
Sequence: MVSFESSFERGTDFLNRNFKKCLFACISIFIFALLALSFLSLLQPDTVQRLYQCAVPSMIYVPPMINEAISIQHEEFNNRRRRLSAALREDKLDALIMEPTVSMDYFANITTGSWGLSERPFLGIIFSDDEPYPGDVASRIYFLVPKFELPRAKELVGKNIDAKYITWDEDENPYQVLYDRLGPLKLMIDGTVRNFIAQGLQYAGFTTFGVSPRVASLREIKSPAEVDIMSRVNIATVAAIRSVQPCIKPGITEKELAEVINMLFVYGGLPVQESPIVLFGERAAMPHGGPSNRRLKKSEFVLMDVGTTLFGYHSDCTRTVLPHGQKMTERMEKLWNLVYDAQTAGIQMLSHLSNTSCAEVDLAARKVIKDAGYGEYFIHRLGHGLGLEEHEQTYLNPANKGTPVQKGNVFTVEPGIYIPDEIGIRIEDAVLASDVPILLTNFRAKSPYEP
What are the official names of this protein?
Uncharacterized peptidase C18A7.01.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: ILVD_CHLL2
Sequence: MRSDTVKTGFEKAPHRSLLKATGAIASNNDFRKPFIGICNSFNELIPGHAHLQELGRIAKEEVRKAGGVPFEFNTIGVCDGIAMGHIGMRYSLASRELIADSVETVAEAHRLDGLVCIPNCDKITPGMMMAALRINIPVIFVSGGPMKAGCTPSGKTVDLISVFEAVGQCSTGEITESELETIQDSACPGCGSCSGMFTANSMNCLSEALGIALPGNGTILAIDPRRNELVREASRKIVDLVNNDIRPRDIITRKSLLNAFALDFAMGGSTNTILHTLAIANEAELDFDFSELNALSAKTPYICKVSPATMDVHIEDVDRAGGISAILKELSRVDGLLDLSAPTVTGKTLGENIAGAEVLDRNVIRSIENPYSATGGLAVLYGNLAPQGAVIKTGAVSPEMMTHTGPAKVYDSQDEAIKGIMDGDICAGDVVVIRYEGPKGGPGMPEMLSPTSAIMGRGLGGSVALITDGRFSGGSRGACIGHVSPEAAEKGPIAALENGDMITIDIPNRCISVDLPETVIAGRIAALKPFEPKIKKGYLARYAQLVTSANTGAIMKNPAYCESK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CSRA_CLOBH
Sequence: MLVITRKKGESLLIGDDIEITVVKLDDGSVKLAIDAPKNLTILRKELYNEVQEENKKATNFNPSILKNIKSK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_FRAT1
Sequence: MAAKQVLFSDEARAKMLDGVNTLANAVKVTLGPKGRNVVLDKSFGTPTITKDGVSVAKEIELEDKFENMGAQIVKEVASKTADVAGDGTTTATVLAQALLTEGLKAVAAGMNPMDLKRGIDKATARLVEELKALSKPCSDPKSIEQVGTISANSDATVGKLIADAMAKVGKEGVITVEEGKGFEDELDVVEGMQFDRGYLSPYFATNQENMTTDLENPYILIVDKKISNIRDLLPILEGVSKSGRALLIIAEDVESEALATLVVNNMRGVVKVCAVKAPGFGDRRKAMLEDIATLTGATFVSEDLSMKLEETNMEHLGTASRVQVTKDNTTIIDGAGEKEAIAKRINVIKANIAEANSDYDREKLQERLAKLSGGVAVIKVGAVTEAEMKEKKDRVDDALHATRAAVEEGIVAGGGVALIRAQKALDGLTGENDDQNYGIALLRKAIEAPLRQIVSNAGGESSVVVNQVKANQGNYGYNAANDTYGDMVEMGILDPTKVTRSALQHAASIAGLMITTEAMIGEIKEAAPAMPMGGGMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPB_BEFVB
Sequence: MDFIRCHVAMQIINFKALEIDKRSLLGILVIKNIKNLHRSNQLLTRLSDLMVPSVIHNGEFVMRNDKSDKLWIFVGESWASLDLEDLNGVRENVFNISKTVPLLIQG
What are the official names of this protein?
Protein beta.
Protein: DDL_ACIBT
Sequence: MSNATKFGKVAVLLGGKSAERAVSLDSGQAVLDALLRSGVQAEAFDPQDRSVTELVNYDRAFIVLHGRGGEDGQIQGVLEWLNIPYTGTGVQGSAIGMDKVKTKQIWQGSDLPTAPYRIITKETDLDSVIAELGLPVIIKPVHEGSSVGMSKVEKAEDFAAAIEKATQHDAVVMAEKWITGREFTISFLNGQPLPVIRLQPPADVAFYDYEAKYQRNDVEYGIPCGLSETEEKKLQALCLRAFQAVGAEGWGRIDAMQDEQGNFWLLEVNTVPGMTSHSLVPKAAKAVGYSFDELCVAILEQTLEGTA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIN_ECO57
Sequence: MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLVFTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD
What are the official names of this protein?
Protein YciN.
Protein: PSIB_RHILP
Sequence: MRSFRAAELPDRNSIASISGLIGSDLIQMIRFDDMHSLFVGEEALRVGLTAFTIFDGYPIPLAGQIALLGGDGSKPYRSPSITMTEAARRFECCRPVLDPVFAPMDRVANKGLIVAGALESLQVRIDRRSPVLL
What is the function of this protein?
Could be involved directly or indirectly in exopolysaccharide synthesis.
What are the official names of this protein?
Protein PsiB.
Protein: CLPX_RICPR
Sequence: MVVDADKKELICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEESKVALKQITASIPTPQKICKILNDYVVGQDQAKKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILLRLLISAEFNIAKAQKGIIYIDEVDKIARKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNILFICGGAFMGIDRIIRSRTNHSSIGFAANINIDKEKSNNEILKSLEIEDLTKFGLIPEFIGRLPIITTLDELDKEALITILTKPKNAIVKQYQKQFELDDADLVIDYSALEAIAEKALVKKTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVDGLIEPCMTSIISTKLNKKQPIIEDIPA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CHLN_PINCO
Sequence: MSTKIVETITLECETGNYHSFCPISCVSWLYQKIEDSFFLVVGTKTCGYFLQNALGVMIFAEPRYAMAELEEGDISAHLNDYEELKTLCIRIRKDRDPSVIIWIGTCTTEIIKMDLEGMAPKLEYEIGVPILVARANGLDYAFTQGEDTVLAVMAHRCPDQEFPIGESKETKKKLFPFPLLKENNLVEYANHPPLVIFGSLPSNLVSQLDTELRRQFIKVSGWLPAQRYADLPSLGDGVYVCGVNPFLSRTATTLIRRKKCELIVAPFPIGPDGTRAWIERICPVFGIEAQSLEEIEERIWESLKDYLDLVRGKSVFFMGDNLIEISIARFLIRCGMIVYEIGIPYLDKRYQAAELALLKKTCIRMCMPIPRIVEKPDNSNQIRRMRELKPDLAITGMAHANPLGARGIGTKWSVEFTFAQIHGFANARDVLELVTRPLRRNENLDNLDRTTLVRKNNK
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: OMPW_VIBAL
Sequence: HKQGDFVLRVGAASVVPNDS
What are the official names of this protein?
Outer membrane protein W, Outer membrane protein 25Va, Omp25Va.
What is the protein family that this protein belongs to?
Belongs to the OmpW/AlkL family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RL22_RHOJR
Sequence: MSNTETANPTAKAVARHVRVTPMKARRVVDLVRGRSVEDALNILKFAPQAASEPVAKVIASAAANAENNLDLDPSTLVVATAFVDEGATLKRFQPRAQGRAFRIRKRTSHITVIVESLPKTGTSTRNRRKGSAQ
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: FABZ_HELAH
Sequence: METSQNPQSQFFIEHILQILPHRYPMLLVDRVVELEANKKIVAYKNITFNEDVFNGHFPNKPIFPGVLIVEGMAQSGGLLAFTSLWGFDPEMAKTKIVYFMTIDKVKFRIPVTPGDKLEYHLEVLKHKGMIWQVGGTAQVDGKVVAEAELKAMIAERD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EI3D1_DROVI
Sequence: MSETINTAAQFPTFEKPTVQFNEKGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTSTSNNDKKYQNKYASTFGTGNQYAYYHEEDETTFHLVDTARVQKPPHQRGRFRNMRNSRSGRGRNARGGLNTHGHGMTTLSSKNVKARDPRRGMGKRFGNRGPPPKMRESSVAVRADWASIEEMDFPRLIKLSLPNIKDGEDITTCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTIGNVFATDAILATIMCSTRSNYSWDIVIEKVGEKIFMDKRDHTEFDLLTVNETSVEPPTDDDSSCNSPRNLAIEATFINHNFSQQVLKTGDQEAKYKFEETNPFISEDEDIQVASVGYRYKKWELGSDIVLVARCEHDGVLQTPSGEPQFLSIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGILRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDGEGFQQVYNYANNSNKI
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-1, eIF3d-1, Eukaryotic translation initiation factor 3 subunit 7-1, Eukaryotic translation initiation factor 3 subunit p66.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_STRPZ
Sequence: MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGAKLEEAINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSEGFLGLDIGPKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_HELMI
Sequence: MSTFMAKAEDVERKWYVIDAADKPLGRVASEAARLLRGKHKPIFTPHVDTGDHVIIINAEKVALTGKKLTQKLYYHHSRYPGGMTLINYGTLLKTRPERAVEKAIKGMLPKNRLGEQMYRKLNVYKGEAHPHQAQKPEAWTIRD
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ROR1_MOUSE
Sequence: MHRPRRRGTRPPPLALLAALLLAARGADAQETELSVSAELVPTSSWNTSSEIDKGSYLTLDEPMNNITTSLGQTAELHCKVSGNPPPSIRWFKNDAPVVQEPRRISFRATNYGSRLRIRNLDTTDTGYFQCVATNGKKVVSTTGVLFVKFGPPPTASPGSSDEYEEDGFCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEVLENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHSFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLCDIPACDSKDSKEKNKMEILYILVPSVAIPLAIAFLFFFICVCRNNQKSSSPPVQRQPKPVRGQNVEMSMLNAYKPKSKAKELPLSAVRFMEELGECTFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYMNQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSSLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNLSNPRFPNYMFPSQGITPQGQIAGFIGPAIPQNQRFIPINGYPIPPGYAAFPAAHYQPAGPPRVIQHCPPPKSRSPSSASGSTSTGHVASLPSSGSNQEANVPLLPHMSIPNHPGGMGITVFGNKSQKPYKIDSKQSSLLGDSHIHGHTESMISAEV
What is the function of this protein?
Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (By similarity).  Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (By similarity).  In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PubMed:27162350).
What are the official names of this protein?
Inactive tyrosine-protein kinase transmembrane receptor ROR1, mROR1, Neurotrophic tyrosine kinase, receptor-related 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cell projection, axon.
Protein: RIMM_STRPM
Sequence: MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDKDQFVQEVTIVSHRKQKHFDIIKLKDMYHINAIEKYKGYTLKVSKANQGDLQEGEFYYHQIIGMAVYEKDRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLNVDVPNKRVDVELMEGLDDED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH_HMPVC
Sequence: MITLDVIKSDGSSKTCTHLKKIIKDHSGKVLIALKLILALLTFFTITITINYIKVENNLQICQSKTESDKEDSPSNTTSVTTKTTLDHDITQYFKRLIQRYTDSVINKDTCWKISRNQCTNITTYKFLCFKPEDSKINSCDRLTDLCRNKSKSAAEAYHTVECHCIYTIEWKCYHHSID
What is the function of this protein?
Viroporin that forms a ion channel probably displaying low ion selectivity (PubMed:24672047).  Plays a role in counteracting host innate immunity by inhibiting TLR7/MyD88/TRAF6 signaling and STAT1 phosphorylation, leading to down-regulation of type-I IFN (PubMed:27131212, PubMed:29789500).
What are the official names of this protein?
Small hydrophobic protein.
What is the protein family that this protein belongs to?
Belongs to the metapneumovirus small hydrophobic protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: TXP1_PHLXX
Sequence: ACLGQWDSCDPKASKCCPNYACEWKYPWCRYKLF
What is the function of this protein?
Voltage-gated sodium channel inhibitor.  It is unclear if it selectively inhibits Nav1. 7/SCN9A or shows similar potency on all sodium channels tested (Ref. 1, PubMed:31234412, PubMed:31443554).  According to Escoubas et al. , 2006 and Nicolas et al. , 2019, it is selective over Nav1. 7/SCN9A (90% inhibition at 1 uM), versus Nav1. 4 and Nav1. 6 (35% inhibition), and shows a small inhibition on all other sodium channels (except Nav1. 8/SCN10A) (Ref. 1, PubMed:31234412).  According to Goncalves et al. , 2019, it shows a similar inhibition on almost all sodium channels tested (Nav1. 1/SCN1A (IC(50)=280. 3 nM), Nav1. 2/SCN2A (IC(50)=73. 7 nM), Nav1. 3/SCN3A (IC(50)=201. 5 nM), Nav1. 4/SCN4A (IC(50)>2100 nM), Nav1. 5/SCN5A (IC(50)=710. 6 nM), Nav1. 6/SCN8A (IC(50)=491. 2 nM), and Nav1. 7/SCN9A (IC(50)=254. 3-260 nM)), except Nav1. 8/SCN10A (PubMed:31443554).  The voltage-dependence of steady-state Nav1. 7/SCN9A channel activation and inactivation are not affected, suggesting that is does not act as a gating-modifier toxin but rather blocks or impedes ion flux through the channel pore (Ref. 1, PubMed:31234412).  The toxin effect is partial and poorly reversible (PubMed:31234412).  In addition to its inhibition to sodium channels, it also shows a small inhibition on rat Kv3. 4/KCNC4 potassium channels (20% inhibition at 1 uM) (PubMed:31234412).  In vivo, when tested on pain models, it shows analgesic activity (PubMed:31234412, PubMed:31443554).
What are the official names of this protein?
Mu-theraphotoxin-Pspp1, Mu-TRTX-Pspp1, Phlotoxin 1, PhlTx1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1493_LISIN
Sequence: MPKILVDADACPVKAEIKQVAEQFQLDVIFVASFNHYSVNTNGENWIFVDTGKESADMRMMNLANKGDIIVTQDIGLASILLAKGTYVFSNRGELYREEEMSLMLDIRYRHAKERQQGKYSKGPKAMSDQDRVLFKDRMTTFFKNK
What are the official names of this protein?
UPF0178 protein Lin1493.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.