PharMolix/UniProtQA huggingface dataset:
Protein: SKG1_YEAS6
Sequence: MTASTSVAVGCAVGIPVGVGIIIAVCFWFNLQKRYKREEQDDRELERAIYDESGFVSFDNFGPLRDSKDEAALASSELKNPDHTSGSSEGSAHPEEKDGKSRDQEKPLGKKNSKYYVPAYRRKINLLQVRNNNYGNNARQKSVVDLPSINNSSNVSLSSSQRHITKRQISVYDQMVPVISDEGPKFFADPSSDTNTSNDQNKASMIELKHNTRQSINENLIRKLQNQDFGSYYPRRASSSFLNGNISNASFHTRNSSITSVNKRDALEDVFATPKSAAQSQLPNTFDKDNEGIDADHSVKDSRSAITDKDKDIYKLQNNYDVGNIGEIAEEDQYENEFTNYSQSKREFIESLRPK
What is the function of this protein?
Plays a role in cell wall integrity.  Affects the cell wall polymer composition in the growing region of the cell (By similarity).
What are the official names of this protein?
Suppressor of lethality of KEX2 GAS1 double null mutant protein 1.
What is the protein family that this protein belongs to?
Belongs to the SKG1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein; Cytoplasmic side. Bud membrane; Single-pass type III membrane protein; Cytoplasmic side. Note=Localizes on the inner surface of the plasma membrane at the bud and in the daughter cell. Localizes at an incipient bud site in the cells with emerging buds, a bud tip in small- or medium-budded cells, and a cell periphery in large-budded cells.
Protein: TRMD_ECOSM
Sequence: MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 010R_FRG3G
Sequence: MKMDTDCRHWIVLASVPVLTVLAFKGEGALALAGLLVMAAVAMYRDRTEKKYSAARAPSPIAGHKTAYVTDPSAFAAGTVPVYPAPSNMGSDRFEGWVGGVLTGVGSSHLDHRKFAERQLVDRREKMVGYGWTKSFF
What are the official names of this protein?
Uncharacterized protein 010R.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: RDRP_I86A3
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTEIGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNDLTSNESGRLMDFLKDVMESMNKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNRKSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARRICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAGMLASIDLKYFNDSTKKKIEKIRPLLVDGTASLSPGMMMGMFNMLSTVLGVSILNLGQRKYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKTGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYKGRLCNPLNPFVSHKEIESVNSAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: FADA_ECO24
Sequence: MEQVVIVDAIRTPMSRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAARMIMSGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGISREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEALATLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCDPAIMGYGPVPASKLALKKAGLSVSDIGVFEMNEAFAAQILPCIKDLGLIEQIDEKINLNGGAIALGHPLGCSGARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDXA_CERS4
Sequence: MSEPLYAPRTPIFPRQISGAFRTAKWWILAVSLGIYLLTPWLRWDRGPNLPDQAVLIDIAGRRFFLFGIQIWPHEFYFVAGLLIMAGLGLFLFTSAAGRVWCGYACPQTVWTDLFLLVERRIEGDRNAQIRLHRQAWTAEKVWKRLLKWSVWAAISLLTGGAWVFYFADAPTLLNGLVTLTAHPVAWITIFVLTATTFVFAGFMREQICIYACPWPRIQAALMDEETITVAYRDWRGEPRGKRSETGRGDCIDCMACVNVCPMGIDIREGQQMACITCGLCIDACDDTMDRIGRPRGLIGYLALSDEHLERAGDTPKPAWRRLFRLRTSLYAVLWAGVGVTLIAALLLRPAVDLAVTPVRNPLFVTLSDGSIRNAYELRLRNMSGEDRRFRLAVDGSAGLRPSIEGSAGLDVPVAANATGLVRLYLTAPQGSDPATGALTDLRIRLDDAGGPEGGPVAAVKAAFHGARS
What is the function of this protein?
Predicted to be involved in a redox process.
What are the official names of this protein?
Protein RdxA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YFF7_SCHPO
Sequence: MASFHIIVSYVTVVLAIIIAITFAARRFWISRYRSIRYSPVENSFEADFNNGLNSSSFDIAQNILAQDTRAGLDEAATSQIRGLMKQLQCSFDQARLIYIRKVMSDNNVDSTGMPLDNKAVTKL
What are the official names of this protein?
UPF0357 protein C1687.07.
What is the protein family that this protein belongs to?
Belongs to the UPF0357 family.
Protein: SYK2_METAC
Sequence: MTMEINNTDPSENMPLPDDVDLSGSRAFDDSKLAKLNGIISQGLDPYPYRFEKNGDICEILVKFEDFEKNEGLSVRTAGRLYNIRKHGKMIFADLGDQTGRIQVLIRKGNLPDEEFATFKNLMDSGDIIGIQGELFRTKRGENSISVSEFSLLSKSLCALPEKFHGLKDVETRYRKRYLDLIVNAEKREIFVMRSKLISEIRRFLADREFLEFETPILQTVYGGANARPFKTFHNCLGQNLFLRIAPELYLKRLVVGGYEKVFEISKNFRNEDIDTTHNPEFTMIEVYEAYRDYNDMMDLTEALISELVFRLTGGYEVKMGENTINLRSPWKRISMEGALKEYAGLDVFSHSLEELKQIAIQNRIEDYEKAKSHGEFLALLFEGLVEDKLVNPTFIYDFPVENSPLAKNHREKEGFVERFELFLNGWELANGYSELNDPLEQEKRFEEQDKKRKLGDLEAQTVDYDFINALGYGLPPTGGMGLGIDRLTMILAGLESIKEVILFPQMKRED
What are the official names of this protein?
Lysine--tRNA ligase 2, Lysyl-tRNA synthetase 2, LysRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHE1_STAA9
Sequence: MAVQLVLNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRVLPGRFYVITLYRIIKLVIIFLIELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQIVLLSNLITLTPGTVVLGVSDDRTKIYIHAIDFSTKEQEVESIKTSLEKIVREVGEI
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit E1, Mnh complex subunit E1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANC_ECOLC
Sequence: MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQVGERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLIDNKMVELA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_CHICK
Sequence: MSGGLDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNIPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQTEWTAPAPEFTAPPQPEVADWSEGVQVPSVPIQQFPTEDWSAQPATEDWSAAPTAQATEWVGTTTEWS
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Also functions as a cell surface receptor for laminin.  Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.  May play a role in cell fate determination and tissue morphogenesis.
What are the official names of this protein?
40S ribosomal protein SA, 37 kDa laminin receptor precursor, 37LRP, 37/67 kDa laminin receptor, LRP/LR, 67 kDa laminin receptor, 67LR, Laminin receptor 1, LamR, Laminin-binding protein precursor p40, LBP/p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus. Note=67LR is found at the surface of the plasma membrane, with its C-terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus.
Protein: RBL_PINRA
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEETQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRIHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREACKWSPELAAACEIWKEIKFEFDVIDRL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MT2_STECO
Sequence: MDPNCSCTAGGSCACPGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-2, MT-2, Metallothionein-II, MT-II.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: CYB_PARGO
Sequence: MMKERMRFKSNLFKIVNGVLIDLPSPRNFTFWWNFGSLLGLVLSIQLVTGIFLAMHYSCDSLLSFESVCHILRDVNEGWIIRLVHANGASFFFICLYCHIGRGMYFGSYMQTKTWIMGVLLFILVMAAAFLGYVLPWGQMSFWGATVITNLFSAIPYIGGDLVYWMWGGFSVGNSTLTRFFSLHFLVPFLVSLGAMLHIFFLHTTGSNNPLGVVADSDKIPFHIYYSAKDLLGFFFMFFFIIFISFLYPNLLGEPDNFIPANPLLTPHHIVPEWYFLFAYAILRSIPNKLGGVLGLLCALLVLFSLPLTHSNFFKSNALYIISRYFFWLFIVSFLMLTIGGGQPVCEPYVMCSQVWSCLYFTYFILCGPLRIFQDYYL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IF2_BURP6
Sequence: MASNNVAQFAAELKMPAGVLLEQLQAAGVQKASEDDALSETDKARLLDHLRKSHGATDGDKRKITLTRRHTSEIKQADATGKARTIQVEVRKKRTFVKRDDVSETGADQAQAQTDEQAEAELKRREEEARREAELLEKQAQELRERQERLEREEAERRAREEAAEAERRRAEEEAAAKRAAAAQAEAAQQAAAAREQAQRAQSEPAEQSAQDEARAAAERAAQREAAKKAEDAAREAADKARAEQEEIRKRREAAEAEARAIREMMNTPRRAQVKAVEPPKPAEPPAAKAAEAKGTLHKPAKPAGEAAAARPAAKKPASGAPAPAAAPAGDRTKKPGTGKSGWQDDAAKRRGIKTRGDSSGGVDRGWRGGPKGRGKHQDSASSFQAPTEPIVREVHVPETISVADLAHKMSIKASEVIKVMMKMGQMVTINQVLDQETAMIVVEELGHRALAAKLDDPEALLVEGEIGSDAEQLPRPPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAISHAKAGGVPIVVAINKIDKPEANPDRVKQELVAEGVVPEEYGGDSPFVPVSAKTGAGIDDLLENVLLQAEVLELKAPVESPAKGIVIEAKLDKGKGPVATVLVQSGTLSRGDVVLAGTAYGRVRAMLDENGKPTKEAGPSIPVEIQGLSEVPGAGEEVIVLPDERKAREIALFRQGKFRDVKLAKQQAAKLESMLEQMGEGEVQNLPLIIKADVQGSQEALVQSLLKLSTDEVRVQIVHSAVGGISESDVNLATASKAVIIGFNTRADAQARKLAEANGIDIRYYNIIYDAVDEVKAAMSGMLAPEKREVVTGMVEVRQVFKVPKVGTVAGCMVTDGVVKRSSSVRVLRNNVVIFTGELDSLKRFKDDVKEVKQGFECGMSLKNFNDIVEGDQFEVFEVTEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPL_STAA3
Sequence: MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDEYRNNILKDSALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDALIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
What is the function of this protein?
Required for the development of induced thermotolerance.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpL.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpL subfamily.
Protein: CNN1_MUSPF
Sequence: MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGSNFMDGLKDGIILCEFINKLQPGSVKKVNESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKGNKVNVGVKYAEKQERKFEPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPTHNHHAHNYYNSA
What is the function of this protein?
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction.  It is capable of binding to actin, calmodulin and tropomyosin.  The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
What are the official names of this protein?
Calponin-1, Basic calponin, Calponin H1, smooth muscle.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
Protein: HEM3_RICM5
Sequence: MTNSIRIGTRKSPLALIHTNLVIQQIKQFFPDINCKIVPIITSGDLIQNKPLYDIGGKALFLKEIEQALLDKKIDLAVHSLKDVPGRIPEPLVIAAVLEREDPRDVFVCLKYKSIEELPQNAVIGSSAVRRKAFIQKIRPDLKVTVFRGNVDSRIKKLMTGEVDATILAYTGLKRLEAFNPEYCHLIEYSQMLPCIGQGVIAVEIRKDDNAMLKICNQINHLPTFELIKPERAFLEYLDANCRTPIAAYSQYLDADPRHLSKLAYRKAFEGNTEALATAAYKSDRTDASTGLTYKLPLEVEFGKMSNIQTDFMLGNLDGSKITFHTETTNIKTSTEAGIKAAKMMLEAICK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RS15_STAA3
Sequence: MAISQERKNEIIKEYRVHETDTGSPEVQIAVLTAEINAVNEHLRTHKKDHHSRRGLLKMVGRRRHLLNYLRSKDIQRYRELIKSLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y1697_SYNY3
Sequence: MVKSVSLLRSQSYEAGSLLASLRTLLEPLGGMGNFVKPGDRVLLKPNLLTGNRPGRECITRPEVVAAVAQLVQEAGGKPFMGDSPAFGSARGVAENNGYLPLLQALDIPIVEFRGGRYATDSDSFNHLRLSKEAMDADVVINLPKLKSHAQLTMTMGVKNLFGCVPGKMKAWWHMEAGKDANRFGEMLVETAKAIAPDLSILDGIMAHEGNGPMHGDPREVGLLAASPDVFALDFVITDILQLDPATIPTMAAQERLGLNPTAAELTFPLSHPRELVVDNWKLPEVLMPIDFGLPRVLRSTFKHFYIRFVKEPLHIYTGKA
What are the official names of this protein?
Thylakoid-associated protein sll1697.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IMP2L_SCHPO
Sequence: MANPFVRNQSFKSVFFKNLVGITLWVPVLMFVEQHVVSVGTIEGRSMKPAFNPETNMLQRDRVLLWKWNKDYKRGDVVILRSPENPEELLVKRVLGVEYDIMKTRPPKKLSLVPVPEGHVWVEGDEQFHSIDSNKFGPVSTGLITAKVIAILFPFSRAGRIDHEGFRKNAVFLSGKRSVK
What is the function of this protein?
Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space.
What are the official names of this protein?
Mitochondrial inner membrane protease subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family. IMP2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NUON_SALHS
Sequence: MTITPQHLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNQEEFYLLVLIASLGGILLANANHLAALFLGIELISLPLFGLIGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGNLSFEALGKSLGDGMLHEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAVRVVLGIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPFRGPDADSLYSYRGLFWHRPVLAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQASLWWLVAAVVVGSAIGLYYYLRVAVSLYLHAPQQPGRDAPTNWQYSAGGIVVLISALLVLVLGVWPQPLISLVQLATPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DUTL_HUMAN
Sequence: MPVIPALGEAKGEVLPPGDTTTIIPLNWMLKSPPGHFGLLLLLSQQAKNGVMVLAGVTDPEYQDEISLLLHNEGHLKEVKMEGARLGLPGRAESLEHQVQSHLNMIAQSQRTFQKKDAGKAIILSKLTQEQKTKHCMFSLH
What are the official names of this protein?
Putative inactive deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323, dUTPase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: AQP9_HUMAN
Sequence: MQPEGAEKGKSFKQRLVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGAVIGGLIYVLVIEIHHPEPDSVFKTEQSEDKPEKYELSVIM
What is the function of this protein?
Forms a water channel with a broad specificity.  Also permeable glycerol and urea.  Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines.
What are the official names of this protein?
Aquaporin-9, AQP-9, Aquaglyceroporin-9, Small solute channel 1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEXH1_ARATH
Sequence: MPPHGPNSQGGRRGGGHSSGRRGGRGGGGRGGGGGGRGEQRWWDPVWRAERLRQQQAEMEVLDENEWWNKIEQWKTGGEQEMLIKRNFSRGDQQTLSDMALQMGLYFHAYNKGKALVVSKVPLPDYRADLDERHGSTQKEIKMSTETERKLGSLLKTTQESGSSGASASAFNDQQDRTSTLGLKRPDSASKLPDSLEKEKFSFALKERQEKLKATESVKALKAFREKLPAFKMKEEFLNSVSQNQVLVVSGETGCGKTTQLPQFILEEEISSLRGADCNIICTQPRRISAISVASRISAERGESIGESVGYQIRLESKRSDQTRLLFCTTGVLLRRLIEDPNLTNVSHLLVDEIHERGMNEDFLLIILRDLLPRRPDLRLILMSATINADMFSTYFGNSPTMHIPGFTFPVAELFLEDVLEKSRYNIKSSDSGNYQGSSRGRRRESESKKDDLTTLFEDIDINSHYKSYSSATRNSLEAWSGAQIDVDLVEATIEHICRLEGGGAILVFLTGWDEISKLLEKINMNNFLGDSSKFLVLPLHGSMPTVNQREIFDRPPPNKRKIVLATNIAESSITIDDVVYVVDCGKAKETSYDALNKVACLLPSWISKASAHQRRGRAGRVQAGVCYRLYPKVIYDAFPQYQLPEIIRTPLQELCLHIKSLQVGSIGSFLAKALQPPDALAVENAIELLKTIGALNDVEELTPLGRHLCTLPVDPNIGKMLLIGAIFQCVNPALTIAAALAYRSPFVLPLNRKEEADEAKRYFAGDSCSDHIALLKAYEGYRDAKRGGNEKDFCWQNFLSPVTLRMMEDMRNQFLDLLSDIGFVDKSKPNAYNQYSYDMEMISAVLCAGLYPNVVQCKRRGKRTAFYTKELGKVDIHPGSVNARVNLFSLPYLVYSEKVKTTSVYIRDSTNISDYALLMFGGNLIPSKTGEGIEMLGGYLHFSASKNILELIQRLRGEVDKLLNKKIEDPSLDITVEGKGVVSAVVELLRSQKH
What are the official names of this protein?
DExH-box ATP-dependent RNA helicase DExH1.
What is the protein family that this protein belongs to?
Belongs to the DExH box helicase family.
Protein: SECE_STAA8
Sequence: MAKKESFFKGVKSEMEKTSWPTKEELFKYTVIVVSTVIFFLVFFYALDLGITALKNLLFG
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS16_LEUCK
Sequence: MSVKIRLKRMGAKKRPFYRVVIADSRSPRDGRFIETVGTYNPIAQPAEIKLDEAKILTWLSNGAQPSDTARNLLSNAGILAKFAEVKAAKKSTAAKPAASATKPTEKNTVAEIKAYLDAQGTQYASSAKKADLLALV
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: EFTS_SHESW
Sequence: MAISAAQVKELRDRTGAGMMDCKKALEETNGDMELAIDNMRKSGAAKAAKKAGNIAADGTILIKNGEGFAVLLEVNCQTDFVAKDANFLGFANSVLDVAAASKVALEDLKAQFEEARVALVAKIGENINVRRVEYIDGAKLASYRHGERIGVVVTGDADDETLKHIAMHVAASKPEYVNPEDVPADVVTREQALQIEISMNEGKPADIAEKMVVGRMKKFTGEISLTGQAYIMEPKKTVGEFLKEKGAKVTNFIRLEVGEGIEKKEEDFAAEVAAQIAASKKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.