PharMolix/UniProtQA huggingface dataset:
Protein: COAD_BACFN
Sequence: MRRAIFPGTFDPFTIGHYSVVQRTLTFMDEVVIGIGINENKNTYFPIEKRVEMIRKFYKDEPRIKVESYDCLTIDFARQVDAQFIVRGIRTVKDFEYEETIADINRKLAGIETILLFTEPELTCVSSTIVRELLGYNKDISMFIPKGMEM
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_OPITP
Sequence: MSLRIVHYNDPVLRRKGEKITAFDKALSQLAKEMLATMQEAAGIGLAAQQIGRPVQLCVVDLRRAEIDFTWELDGAKPPLDLIMPMIITNPEITPDRETDVYLVEEGCLSFPKIRGDVPRPDAITVRYQDEHGTPHTLHCDGLLARCIQHEVDHLNGVLFIDRMEKKTRAAIDADVKTLAKITRAAAKLNPA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PHI3_MYTCA
Sequence: AKAKRSPRKKKAAVKKSSKSKAKKPKSPKKKKAAKKPAKKAAKKK
What is the function of this protein?
Involved in nuclear basic protein transition: histones are replaced by spermatid specific proteins which are themselves replaced by protamines in late spermatids.
What are the official names of this protein?
Sperm-specific protein Phi-3, PL-IV.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: LNBY_BIFL2
Sequence: MPRRHRFAAAIAAVAVAAVLLVTLTVAVVTHGDGAFAPAGTPAGAGASAGIGSDTGSNASEDSDMFPTIVFGDTVIERKEYVAALKAQHGAARLYFRQTYGVDPAEDGWDKAHDGEVPCRWLASRAIDELRRRHAAYLIGVDLGQVADDSYASIVARMEAVNSGNAELKSDGGIVYGRTGFDIDSYLSYELSALKNAYTGDESNPGMSLSDDEVRRYYDEHDWTKDGVDGKTPLDEVRGNVKAQMRSERYDELVSQRAEAIDVTDLPWDALYRFTAGRLG
What is the function of this protein?
Chaperone required for active expression of the lacto-N-biosidase LnbX.
What are the official names of this protein?
Chaperone for lacto-N-biosidase.
Protein: BTUB_CITFR
Sequence: MIKKSLLCTALSVTAFSGWAQDTRPDTLVVTANRFQQPRSAVLAPITVVTRQDIDRWQSTSVNDVLRRLPGVDIAQYGGMGQNSSISIRGTNASHVLVLIDGVRLNLAGVSGAADLSQFPVSLVQRIEYIRGPRSAVYGSDAIGGVVNIITTREKPGTELTAGVGSNGYQNYDVSTQQQLGENTRVTLMGDYAYTKGFDVVAYGSTGSQAQPDKDGFLSKTLYGALEHNFSDTWSGFVRGYGYDNRTNYDSYYSPGSPLLDTRKLYSQSWDAGLRFNGELIQSQLVSSYSHSKDYNYDPDYGRYDSSATLDEMKQYNVQWSNSIVVGHGNVGAGVDWQKQTTEPGTGYVTDGYDQRNTGLYLTGLQQLGDFTFEGAARSDDNSEFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQLHGYYGNSNLDPEQSKQWEGAFEGLTAGVNWRVSGYRNDIDDMIDYDPHTEKYFNEGKVRIKGVEATANFDTGPLAHTLSYDMVDSRNAITDKPLARRSKQQVKYQLDWQVYDFDWGLTYHYLGTRYDTDYVTYQPVKMGGVSLWDLAVSYPITSQLTVRGKIANRFDKDYETVYGYATAGREYTLSGSYTF
What is the function of this protein?
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
What are the official names of this protein?
Vitamin B12 transporter BtuB, Cobalamin receptor, Outer membrane cobalamin translocator.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: MARH2_XENTR
Sequence: MTTGDCCHLPGSLCDCTGSATFLKSLEESDLGRPQYVTQVTAKDGQLLSTVIKALGTQSDGPICRICHEGGNGERLLSPCDCTGTLGTVHKTCLEKWLSSSNTSYCELCHTEFAVERRPRPVTEWLKDPGPRNEKRTLFCDMVCFLFITPLAAISGWLCLRGAQDHLQFNSRLEAVGLIALTIALFTIYVLWTLVSFRYHCQLYSEWRRTNQKVLLLIPDSKTAPTTHHSLLSSKLLKSASDETTV
What is the function of this protein?
E3 ubiquitin-protein ligase which may be involved in endosomal trafficking.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF2, Membrane-associated RING finger protein 2, Membrane-associated RING-CH protein II, MARCH-II, RING-type E3 ubiquitin transferase MARCHF2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Protein: TDH_BOVIN
Sequence: MPVVRVLRRVACWMLQSPACGCRAPVLPSRFLGTSPRQIPMDANFHSTSFSEADQQRVLITGGLGQLGVGLASFLRKRFGKDNVILSDIRKPPEHVFLSGPFIYSDILDYKNLREIVVNNRITWLFHYSALLSAVGEANVSLARAVNITGLHNVLDVAAEHGLRLFVPSTIGAFGPTSPRNPTPDLCIQRPRTIYGVSKVHAELMGEYYYYRYGLDFRCLRYPGIISADSQPGGGTTDYAVQIFHEAVKNGRFECNLKPDTRLPMMYIDDCLRATLEVMEAPAESLSMRTYNISAMSFTPEELAQEVLKHVPELQVTYNVDPVRQAIADSWPMNFDDSNARKDWGWKHDFDLPELVTTMLNFHGSESRVAQAN
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate, mediating L-threonine catabolism.
What are the official names of this protein?
L-threonine 3-dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TSAD_ESCF3
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_CELJU
Sequence: MATLLQIKSSLFGDNGNSSQLANEFVERWKTQNPNGEVVIRDFAKEDVPHLDATRVQALFTPAEQRTAEQQAVVEYSDKIIAEIQAADAIVLGVPLYNFGIPSTLKAYFDHIARAGVTFKYTETGPVGLLTDKPVYILAARGGIYKGQPSDTQSRYLVDFLNFVGLKDIHFIYAEGLNMGQKDQAFASAKHEIEQEIAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: TRUD2_METMP
Sequence: MPININKFILDMERFDGTLKKYPEDFIVEEITPEGTVLEVGKEIGFEDVEKWHGSFIHFTVEKTNWNTMDALKQIVRATKTKRKNFGFAGTKDKFAVTTQRFGCFGLKKEQLENINIKDIVIRDVQKTNKKLRMGGLWGNKFTIKIRDLNLSEKEIKRISDLKLDYVLNYYGIQRFGLIRPITHIVGKFIYERDFESAFYTYCGTPINETGDSLEARQLVDMGEFKKALKLFNRGHDYEKRLIQQYLKYKDFKMAFTALPPQLNSMFVNAYQAYLFNEMINKRFDYGFDELEGDILEDNTPTGTLIGYDTKFSGGIQGEIEKEIVERENLDLKKFKIEDFGNFYGTRRKMVTPIYDFKSRFENEIFELSFKLERGNYATIVTREFTGNLS
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D 2, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D 2, tRNA-uridine isomerase D 2.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: SET3_YEAST
Sequence: MSVPNSKEQSLLDDASTLLLFSKGKKRAEEASKIGSKTDTIEHDESHEREKKGAIEMAAAALATASTVSLPLKKATEQSAAEAATSTAAKEETENQPQKQPQWPVPDSYIVDPDAGIITCICDLNDDDGFTIQCDHCNRWQHAICYGIKDIGMAPDDYLCNSCDPREVDINLARKIQQERINVKTVEPSSSNNSASNKNNGRDRASSTTISDVGDSFSTDQDNTNHRDKRRKRNPSNNSIDSKNESASVNSSDGLTSMPKKKEHFLSAKDAYGAIYLPLKDNVFKSDLIEPFLNKHMDDNWVIQYPHKTFKSVSIEVKPYADIAYSRTYPGFTKLGVYLKKDCIKGDFIQEILGELDFYKNYLTDPRNHYRIWGTAKRRVIFHSHWPIYIDARLSGNSTRYLRRSCQPNVELVTIKLQDTDNRNDKSSGRKSSRIKFVLRALRDISEDEELYIKWQWDSKHPILKLIKGMTIDSLDDLERYGLINSVETILSNGECGCGNNSKDCYLLKVKRYAQSLYKSVKSRGKMNNRYKLNEILNQYNCKKRREPPILHRLEEKAQNTIERAPILLNNFYRQKFLNRNNGPKIPQKNTIDSTNNPDDIAKPFKFALFAQHSSNISVPKKNETSEKPLIITKSTDYDESHITNIEELPIPVLLPINKTSRQTANDVEESQSKNEHKLSRTPSLSNFNKELSKEAQHSQAKTKEIMTEASVNSRRESTPESIMHLSDFSSSQLHSKKKLSFADYRKKLLK
What is the function of this protein?
Transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin.  Required for both gene activation and repression.  Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis.  Required for the transcriptional activation of genes with high activity.
What are the official names of this protein?
SET domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the SET3 family.
Protein: COFC_METJA
Sequence: MNCGIKMKVIIPVSPINSLKTRLSEFLSGEERKNLLLNMLKDIIKALDGLDIVIVSRDEEILDFAKNELKAETIKEKYKGLNNAIKQAFEEIEDKEVIIIPADIPLIKKKHIEDILKLSKNYDLIIAPSRGGGTNLLYLKSKDLIEIKYEGFSFLKHLEEAKKRNLRYYIYDSFLISVDINTPEDLGEIFIHGNDTYTKNYLKSLGIDVEPKHSSAGRFVVKRR
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (PubMed:18260642, PubMed:31469543).  Is able to utilize other purine nucleotides including ATP, dGTP and ITP as cosubstrates in place of GTP but with a lower activity.  Does not display lactate kinase activity (PubMed:18260642).
What are the official names of this protein?
2-phospho-L-lactate guanylyltransferase, LP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: SYN_ECO24
Sequence: MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWVSTPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGTP_SALPA
Sequence: MASIDFRNKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKEQNRLEEYGLDALTGPFESIVEMACLMHDIGNPPFGHFGEAAINDWFRQWLHPEDAESQPLTHDRCVVSSLRLQEGEENLNDIRRKVRQDICHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGPVPDSHRYLMKKPGYYLSEEKYIARLRKELQLAPYSRFPLTWIMEAADDISYCVADLEDAVEKRIFSVEQLYHHLYHAWGHHEKDSLFELVVGNAWEKSRANTLSRSTEDQFFMYLRVNTLNKLVSYAAQRFIDNLPQIFAGTFNQALLEDASGFSRLLELYKNVAVEHVFSHPDVEQLELQGYRVISGLLDIYQPLLSLSLNDFRELVEKERLKRFPIESRLFQKLSTRHRLAYVEVVSKLPTDSAEYPVLEYYYRCRLIQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: GTSF1_MACFA
Sequence: MEETYTDSLDPEKLLQCPYDKNHQIRACRFPYHLIKCRKNHPDVASKLATCPFNARHQVPRAEISHHISSCDDRSCIEQDVVNQTRSLRQETLAESTWQCPPCDEDWDKDLWEQTSTPFVWGTTHYSDNNSPASNIVTEHKNNLASGMRVPKSLPYVLPWKNNGNAQ
What is the function of this protein?
Required for spermatogenesis and is involved in the suppression of retrotransposon transcription in male germ cells.
What are the official names of this protein?
Gametocyte-specific factor 1, Protein FAM112B.
What is the protein family that this protein belongs to?
Belongs to the UPF0224 (FAM112) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CI040_HUMAN
Sequence: MAKRRAAEPVTFHVPWKRLLLCDFAEQPPPPPLWIRPPGVAHAGQLLGVPEQHRKRKIDAGTMAEPSASPSKRRDSGDNSAPSGQEREDHGLETGDPPLPPPPVLPGPGEELPGARLPGGGGDDGAGRAGPPRGDWGVASRQHNEEFWQYNTFQYWRNPLPPIDLADIEDLSEDTLTEATLQGRNEGAEVDMES
What are the official names of this protein?
Uncharacterized protein C9orf40.
Protein: KAX2Y_CENLM
Sequence: KVIDVKCTSPKQCLPPCKAQFGD
What is the function of this protein?
Potent selective inhibitor of Kv1/KCNA voltage-gated potassium channels.
What are the official names of this protein?
Hongotoxin-4, HgTX4, Potassium channel toxin alpha-KTx 02.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARY1_CHICK
Sequence: MNLEEYFARTGYKGSLENQDLETLTDIFQHHIRAVPFENLSIHCGEKITLELEHVYNKIVHKKRGGWCMENNQLLGWVLKCLGYDTSFLGAYVFNPHENAYATIMTHLLVKVVIEGKAYIVDAGFGVSYQMWQPMELVSGKDQPQAPGIFRFTEKNAIWYLEKMRRKQYIPNQNFSNSDLLEKKDCRKVYMFSLEPRTVEDFCFQCTYLQTSPDSLFTKKSICTLQTTDGFRALIGWTLTETKYNYKENMDLVEFITLKDEEVEKTLKDKFNITLERKLVPINVKGFYTI
What are the official names of this protein?
Arylamine N-acetyltransferase, pineal gland isozyme NAT-10, Arylamine acetylase.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
Protein: TAT_SIVM2
Sequence: RLIPNRTRHCQPEKAKKETVEKAVATAPGLGR
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: TRPA_CORGL
Sequence: MSRYDDLFARLDTAGEGAFVPFIMLSDPSPEEAFQIISTAIEAGADALELGVPFSDPVADGPTVAESHLRALDGGATVDSALEQIKRVRAAYPEVPIGMLIYGNVPFTRGLDRFYQEFAEAGADSILLPDVPVREGAPFSAAAAAAGIDPIYIAPANASEKTLEGVSAASKGYIYAISRDGVTGTERESSTDGLSAVVDNIKKFDGAPILLGFGISSPQHVADAIAAGASGAITGSAITKIIASHCEGEHPNPSTIRDMDGLKKDLTEFISAMKAATKKV
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RIFK_CENSY
Sequence: MGISQQAASQHLRELEDEGLITRNAEGKGISVMVTDKGRHELLRVYNILHDSLHSRPDHVEITGTLVSGMNEGAYYMSREGYTGQFQERLGYVPFPGTLNVDTDRKHGPEIARLDGMNGTIIDGFTDGKRSYGWVKCFAGTLNGTIPCHLIRLERTHHGSSTVELISKLDIRKETGLDDGGKITIRIPLEQED
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: Y3985_ARATH
Sequence: MSLCCDLQINLNNQFTFFVNQDLISEYSGFLRKMIKQSNKKKKNHKNSRIIIEVEDFPGGSDGFDLVLRFCYGGGISIDVSNVSILHCSSVFLEMTEKLCSSNLLLRTEKFLEGMFYWSWNDIVLCLKSCEQVFLHADSYGLVDKLVFGVLAKIPQNSDVSHVFSSSSPSSSASASASSQSPETAMIRSYSDKRSTSRSFSCRTSNEWWFDDMSILGPKIIEKLINTLGAHDKNNDSLVLTKFLLHYLKTKVPNKSTNKLEYSGLADTAVQGVVFAAKTAFSCRKMFWVLRVLSGFSISKESRIGLERVIGEMLDQATLDDLLIPAGGKGEKGVYDVDLVIRLLKVFVRIGNTEEGDQNLRMRRIGKLIDKYLREISPDQNLKVSKFLEVAESLPDSARDWFDGLYRAINIYLESHPKLSSEDRTKLCRCLNYKKLTLDTCKQLAKNPKIPPNIAVQALKSQQLSNETRPHSREDKNKVNKIWNSRKYLEEKPILVCLKGFDMSEKFEDDLMMNLERKQWNNSEKVSKEKKSEVMSRSVRHGHTHSSSSFPRLC
What is the function of this protein?
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB/POZ domain-containing protein At3g19850.
What is the protein family that this protein belongs to?
Belongs to the NPH3 family.
Protein: RLMH_SHEB9
Sequence: MKLQLIAVGTRMPDWVTRGFEEYQRRFPRDMALELIEIPAGKRGKNADIVRILQKEGEQMLAAIPKGNHIVSLDLPGKNWTTPELATALTKWQLDGRDVSLLIGGPEGLAPACKEAANQSWCLSALTLPHPLVRVVVAESLYRAWSVNTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGMA_MOUSE
Sequence: MQPPRERLVVTGRAGWMGMGRGAGRSALGLWPTLAFLLCSFPAAISPCKILKCNSEFWSATSSGSHAPASDDVPEFCAALRTYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRVRTLPPAGDSQERSDSPEICHYEKSFHKHSAAPNYTHCGLFGDPHLRTFTDHFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPSAFADGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDRDSQGLYLCLRGCPLNQQIDFQAFRANAESPRRPAAASPSPVVPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDGKMLHSNKDKLHLFERTRELPGAVAAAAAAATTFPLAPQILLGTIPLLVLLPVLW
What is the function of this protein?
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system.  Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses.  Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition.  Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway.  It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.
What are the official names of this protein?
Repulsive guidance molecule A, RGM domain family member A.
What is the protein family that this protein belongs to?
Belongs to the repulsive guidance molecule (RGM) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: SECA_CLOBH
Sequence: MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLKHYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLNNEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYFTKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFTGRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIARIDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMVTIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDKLGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVNSHISGVEEEFQTELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYIRKEKEIGEEQIREIERVILLRVVDTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDEDSVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: PSAE_MASLA
Sequence: MVQRGSKVRILRPESYWFQDIGTVASIEQGGTIRYPVIVRFDKVNYAGVNTNNFAEYELVEVEAPKAKPKK
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: YORV_TTV1K
Sequence: MFEPCLYTFTFAVLPFIDKYITNGSVNAANCDISISFTTEYVPDIFCSMLTF
What are the official names of this protein?
Uncharacterized 5.9 kDa protein.
Protein: Y2115_VIBPA
Sequence: MNPVVISVCVMLVLALMRVNVVVALTFSAIVGGLVAGMSLGDTVAAFESGLGGGATIALSYAMLGTFAVAISKSGITDLLAKSVIKRLNGKESAASTTGLKYAVLVALVLVTMSSQNVIPVHIAFIPILIPPLLGVFAKLKLDRRLIACVLTFGLITPYMVLPVGFGGIFLNNILLKNLHDNGLENVVASQVPTAMLLPGAGMIFGLLLAIFVSYRKPREYKETELTVVHETDHSINKQHILVAALGIIAALGVQLYTGSMIIGALAGFMVFTFGGVIAWKETHDVFTKGVHMMAMIGFIMIAAAGFAAVMKQTGGVETLVQSLSTSIGDNKPLAALLMLVVGLLVTMGIGSSFSTIPILATIYVPLSLAFGFSPMATIALVGTAAALGDAGSPASDSTLGPTSGLNADGQHEHIWETVVPTFIHYNIPLIIFGWIAAMVL
What are the official names of this protein?
Uncharacterized membrane protein VP2115, ORF3.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IMPA_MYCS2
Sequence: MTVVGELDPQKLTALVATAAEILDAASVPFVAGHRADSAVRKQGNDFATEVDLAIERQVVRALTEATGIGVHGEEFGGEPIDSPLVWVLDPIDGTFNYAAGSPMAAILLGLLADGEPVAGLTWLPFTGEKYSALVGGPLYSDGKPCPPLGSPTLADSIIGIQTFNIDSRGRFPGRYRVEVLANLSRVCSRVRMHGATGVDLAYVAAGILGGAISFGHHIWDHAAGVALVRAAGGVVTDLTGAPWTVDSKSVLAAAPGVHEKMLEIVKSTGKPEDYL
What is the function of this protein?
Catalyzes the dephosphorylation of inositol 1-phosphate (I-1-P) to yield free myo-inositol, a key metabolite in mycobacteria.
What are the official names of this protein?
Inositol-1-monophosphatase ImpA, I-1-Pase, IMPase, Inositol-1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: GATC_MACCJ
Sequence: MSKITNEQVKHVAHLARLEITEEEATKFSAQLEAILNFADQLEEVDTEGVEPTFHVLDLQNVLREDVAETSLTQEEILKNAAHTEDGQFKVPSILGGGE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.