PharMolix/UniProtQA huggingface dataset:
Protein: HEYL_BOVIN
Sequence: MKRPREPSGSDSESDGPIDVGREGELSQMARPLSTPSPSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGSSKLEKAEVLQMTVDHLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHLNSYAAEMEPSPTPPGPLAFPAWPWSFFHSCPGLSAPSNQLAILGRVPGPMLPNASSLAYPIPGLRAAPLRRAAGTILPARRNLLPSRGASSTRRARPLERPAAPLPAAPSGRATRGSHMAPLLRSPSPVSPGMVGSPAYMAVPAPRPSSPGLAGRPAGAMLCRSWVSEITEVGAF
What is the function of this protein?
Downstream effector of Notch signaling which may be required for cardiovascular development.  Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'.  Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
What are the official names of this protein?
Hairy/enhancer-of-split related with YRPW motif-like protein.
What is the protein family that this protein belongs to?
Belongs to the HEY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNY_FRAAA
Sequence: MDGVLVILLSLVLLVLVALILAVAWLARTARGDRHYGAATRATRSSSGMAASVDALALDDDDGPAVRVLPPVRPAAEGERPAGDAPGAAYGESAAAPDAGLGSPAPRAPHHDAAAAPEPGAAIGGAPTPAAGSPADASDTGRIAETVDTGTVLAVAAVADTPSRVAATEDTSLEAPLRESALRESAPGESASVRRAAEREAAQIVARAEREAAERLARVEREAAEIRRRGEDEVASLRNQARAEAAADASRAEAAVRDAARVELEAARAEIATARTSFEEELRVRRAELRGREEALAAREQRVEERTAGLDEHASRLAGREQDLLDREDELAHRTAEAADDEAARQAALERIAELTAVQARAELVSTIEHEARREAALLVREIEARAEEEGEERARRIVTTAIQRVASDQTTESVVTVLHLPGDEMKGRIIGREGRNIRTFESVTGVNVLIDDTPEAVLLSCFDPVRREIGRITLAALVSDGRIHPHRIEEEYARAQVEVEERCVRAGEDALLETGISEMHPELVTLLGRLRYRTSYGQNVLAHLIESAHLAGIMAAELRMALPLAKRAALLHDLGKALTHEVEGSHALIGADVARRYGESEEVVHAIEAHHNEVAPRSLCAVLTQAADQISGGRPGARRDSLESYVKRLERIEQIAGDRPGVDRVFAMQAGREVRVMVVPEEVDDVAAHLLARDVARQIEDELTYPGQIRVTVVRETRAVGTAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACCE5_MYCTU
Sequence: MGTCPCESSERNEPVSRVSGTNEVSDGNETNNPAEVSDGNETNNPAEVSDGNETNNPAPVSRVSGTNEVSDGNETNNPAPVSRVSGTNEVSDGNETNNPAPVTEKPLHPHEPHIEILRGQPTDQELAALIAVLGSISGSTPPAQPEPTRWGLPVDQLRYPVFSWQRITLQEMTHMRR
What is the function of this protein?
Stimulates activity of the AccA3/AccD5 biotin-dependent acyl-CoA carboxylase complex (PubMed:16354663, PubMed:16385038).  Interacts with AccD5 and modulates its carboxylase activity for acetyl-CoA and propionyl-CoA (PubMed:16354663, PubMed:16385038).  Inhibits activity of the AccA3/AccD6 complex (PubMed:17114269).  Is also required for the activity of the long-chain acyl-CoA carboxylase (LCC) complex (PubMed:28222482).
What are the official names of this protein?
Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase epsilon subunit.
Protein: XPR6_YARLI
Sequence: MLRKFILGLLLASQAVAQLPHKERDYDSRVYVALSLRDGLDPREFEASVSGLDHGQWTFEHPVGTIPNTYVFSAPKEYAPIENIRDQDRLEVAGGVLAKRELRKREKLQKKYGMSEEDVEKRLVALERLDYDWSERGLGSLEVLSERRIHKRAPVNWTEEEMEYLKEIKRRAEEAQKAQDDKGDKKEDQKDDKKEGQEAQKEGDKEDNKGDDKEDGEEDDDDDEDEDDDDASPAMPVQWKPVDESMYGGMPDDSLYDVYRKYYPDEVGIKDPSLWKQWYLHNVHKAGHDLNVTGLWLRNVTGWGVVTAVVDDGLDMNAEDIKANYFAEGSWDFNFNKSDPKPSSHDDYHGTRCAGEIAAVRNNVCGVGVAYDSKVAGIRILSKEIAEDIEALAINYEMDKNDIYSCSWGPPDNGQTMARPGKVVKDAMVNAITNGRQGKGNVFVFASGNGGSRGDNCNFDGYTNSIYSITVGALDFNDGHPYYSEACSANMVVTYSSGSEHYIVGTDINAIDDKSAAPRCQNQHGGTSAAAPLAAGVFALALSVRPDLTWRDMQYLALYSAVEINSNDDGWQDTASGQRFHHQFGYGKLDASKIVELAEGWNLVNNQTSFHSEVKTVSQKVKYNEPLKSVITVTRDDLDKVNFKRAEHITAVLNLEASYRGHVRVLLKGPRGVVSELAALRRDDRSKDGYDNWAFMSVAHWADEGEGDWELTVENTGEQDQVELVNWQLNVFGEQKDKREENKEGESKPEDENKEGEKEGEKKPEDENKEEGNKEDDKGDQKEDKPEDKPEDKPEDTPEDKPEDKPEDAPEDKPSDEKKPEEKPEEKPVDNSDSSSDSSDSHTSWWPDLSSKKSAWLYGAVLLVGGFIAVIGIYACVTRRNRVRRNRSKDAPSASSFEFDLIPHDDSDDDFVYPEDTHRRSGDNDRLYDPFAEVEDDDDMFRISDEGEDAHDVEPELNRVSMEADKRDNDRQNLLG
What are the official names of this protein?
Dibasic-processing endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MSCL_PSEE4
Sequence: MGMLSEFKAFAVKGNVVDMAVGIIIGAAFGKIVSSFVGDVIMPPIGLLIGGVDFSDLAITLKAAEGDVPAVVLAYGKFIQTILDFIIVAFAIFMGVKVINRLKREEAVAPTAPPVPSAEETLLTEIRDLLKAQNRQP
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECE_RICPR
Sequence: MFREYKIYKFFEQVKQETYKVFWPNKKELIASTLVVVATVFIFSLICLVLDYSIHNIMQLLLTIGK
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CYC6_CYAM1
Sequence: MKSLLTFILTTIFCIQQVWAADLAHGEQIFSANCAACHAGGNNVIMPEKTLKLDALEANQMNSVEAISTQVRNGKNAMPSFSRLTDSDIEDVANYVLAQAKKGW
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: MIP_TATMI
Sequence: MKMRLVAAAAMGLAMSTTIAATATTDATTSAPGTSLTTDTEKLSYSIGADLGKNFKKQGIEISPAAMAKGLQDGMSGGQLLLTDDQMKDVLNKFQKDLMMKRSAEFNKKAEENKSKGEAFLNENKSKEGVVSLPSGLQYNILERGDGAKPTKDDVVTVEYTGKLIDGQVFDSTEKTGKPATFKVSQVIPGWTEALQLMPAGSTWEVYIPSNLAYGPRSVGGPIGPNETLIFKIHLISVKKSDA
What is the function of this protein?
Essential virulence factor associated with macrophage infectivity.  Exhibits PPIase activity.
What are the official names of this protein?
Outer membrane protein MIP, Macrophage infectivity potentiator, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: AMPPA_PYRAB
Sequence: MRAKVRILNIRSGHFDVFINPKDAQEWKLHPNDLVKIESGKRSIYGSVVIGDFVESGEVGLSLDILDAYQFSEGELVSITPSETPESVRYIKKKMRGEKLRKVEIETIVRDIVDRKLRNTEISALVTAIEVNGLDMDEIAALTIAMAETGDMLDIDRKPIMDVHSIGGVPGNKTNIIVVPIVAAAGLTIPKTSSRAITSAAGTADVVEVFTNVTLSLDEIKRIVEKIGACLVWGGALNLAPADDLTIHVERRLSLDPRGLMLASIMSKKYAIGSQYILIDIPTGKGAKVETMEEARSLAKDFIELGKKLGQYVEVAITYGGQPIGYTVGPALEAKEALETLMTGKGPGSLVEKALGLAGILLEMGGVAPRGMGKKVAREILESGKAYEKIKEIIEEQGGDPNIKPEDIPIGDKTYTIHAQTSGYVTGIDNKAITAIAREAGAPEDKGAGVKLHVKVGEKVKEGDPLFTIHAESESRLDKAIILARRLEPIKIEGMVLQVLGNL
What is the function of this protein?
Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P).  Exhibits phosphorylase activity toward CMP and UMP in addition to AMP.  Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.
What are the official names of this protein?
AMP phosphorylase, AMPpase, Nucleoside monophosphate phosphorylase, NMP phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: BGLF_ASPFC
Sequence: MRVLSAIALVASLASSALSAPASESRVSTQLRSRDAEGYSSPPYYPAPNGGWLSSWADAYEKAQRVVRDMTLAEKVNLTTGTGIFMGPCVGQTGSALRFGIPNLCLQDSPLGVRNSDHNTAFPAGITVGATFDKDLMYARGVELGKEFRGKGINVLLGPSVGPIGRKPRGGRNWEGFGADPSLQAIGGAQTIKGIQSQGVIATIKHYIGNEQEMYRMSNVGQRAYSSNIDDRTLHEVYLWPFAEGIRAGVGAVMTAYNEVNSSACSQNSKLLNEILKDELGFQGFVMTDWLGQYGGVSSALAGLDMAMPGDGAIPLLGTAYWGSELSRSILNGSVPVSRLNDMVTRIVAAWYKMGQDGDFPLPNFSSNTQDATGPLYPGALFSPSGVVNQYVNVQADHNITARAIARDAITLLKNDDNILPLKKDDALKVFGTDAGPNPDGLNSCADMGCNKGVLTMGWGSGTSRLPYLVTPQEAIANISSNAAFFITDKFPSNVAVSSGDVAVVFISADSGENYITVEGNPGDRTSAGLNAWHNGDKLVKDAAAKFSKVVVVVHTVGPILMEEWIDLPSVKAVLVAHLPGQEAGWSLTDVLFGDYSPSGHLPYTIPRAESDYPSSVGLLSQPIVQIQDTYTEGLYIDYRHFLKANITPRYPFGHGLSYTTFSFSQPTLSVRTALDSTYPPTRPPKGPTPTYPTAIPDPSEVAWPKNFDRIWRYLYPYLDDPASAAKNSSKTYPYPAGYTTVPKPAPRAGGAEGGNPALFDVAFAVSVTVTNTGSRPGRAVAQLYVELPDSLGETPSRQLRQFAKTKTLAPGTSETLTMEITRKDISVWDVVVQDWKAPVRGEGVKIWLGESVLDMRAVCEVGGACRVI
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase F, Beta-D-glucoside glucohydrolase F, Cellobiase F, Gentiobiase F.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YR694_MIMIV
Sequence: MSHFSRCFDECSKIERPNVNKKLTRLIIVLFCLLCIIVTLGVIGYKFLFKMSYVDAIYNTAITTSTLGIAPGDKTDAEKIFTGIYAVLVGVFFISVISAIVSYMFTTYILD
What are the official names of this protein?
Uncharacterized protein R694.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS16_ACISJ
Sequence: MVVIRLSRGGSKGRPFFNIVVADKRVRRDGRFIERLGFYNPSAKEGEEGLRIAQDRLTYWKGVGAQPSPTVDRLIKQAAQKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PLSY_STRE4
Sequence: MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNTFRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKGGKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAHFLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NDEL1_XENTR
Sequence: MENEEIPEFLSPKEEIVYWRELAKRLKQSYQEARDELIEFQEGSRELEAELETQLVQAEQRNRDLLSDNQRLKCEVESLKEKLEHQYAQSYKQVSLLEDELARARSIKDQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQTNGTRKSAPSSPTLDCDKTDSAVQASLSLPATPVGKVCDNSFTPPKGIPNGFGTTPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYTPVGLNSSGGGSSALNSSGVKYSHAGHTSFFDKGAVNGYDPPGVLGSRPPSPPGMLPLSV
What is the function of this protein?
Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome.  Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts.
What are the official names of this protein?
Nuclear distribution protein nudE-like 1.
What is the protein family that this protein belongs to?
Belongs to the nudE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the interphase centrosome and the mitotic spindle.
Protein: AFB1_YEAST
Sequence: MIFAPSFSLIKNILLVSFLISHSFAAKTLTSSSNDDTLARSAAADADMAFFMEFLNDFDTAFPQYTSYMMQNHLTLPQPVADYYYHMVDLASTADLQSDIAQSFPFTQFQTFITAFPWYTSLLNKASATTIYLPQHFITGETEATMTNSSYASQKNSVSNSVPFSTANAGQSMISMANEENSTTALISASNSSSTSRTSQSQNGAHAKSLYFPMALFGIFAVAL
What is the function of this protein?
MATalpha-specific protein that interferes with a-factor, the pheromone secreted by MATa cells (PubMed:24121774).  Contributes to mating efficiency (PubMed:24121774).  Acts to bind and sequester a-factor rather than to degrade it, and promotes the efficient mating of MATalpha cells by keeping the a-factor concentration at the plasma membrane within the narrow range needed for accurate pheromone gradient detection (Probable).
What are the official names of this protein?
A-factor barrier protein 1.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor.
Protein: RL7_CAUSK
Sequence: MSKLEKLVEELSALSVLEAADLSKLLEEKWGVSAAAPVAAAGPAAAAAPAEAAEEQTEFTVVLTAGGDKKINVIKEVRGVRPDLGLKEAKDLVEGAPQNVVENVSKQVAEEIAKKLTEAGATVQVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ECSIT_MACFA
Sequence: MSWVQATLLARGLCRAWGGICRAALPGTSISQVPRQLPRGLHCSAAPHSSEQSLVSSPPEPRQRPTKALVPYEDLFGQAPSGERDKASFLQAVQKFGEHSVRKRGHIDFIYLALRKMREYGVERDLAVYNQLLDIFPKEVFRPRNVIQRIFVHYPRQQECGIAVLEQMESHGVMPNKETEFLLIQIFGRKSYPMLKLLRLKMWFPRFMNINPFPVPRDLSQDPVELATFGLRHMEPDLSARVTIYQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPIFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETPEEWNLYYPMQLDLEYSRSGWDDYEFDINEVEEGPVFAMCMAGAHDQATLAKWIQGLQETNPTLAQIPVVFRLTRATGELHTSSAGLEEPPPPEDHEEDDSRQRQQQGQS
What is the function of this protein?
As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
What are the official names of this protein?
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ECSIT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: MMP20_PIG
Sequence: MKVLPASGLAVLLVTALKFSAAAPSLFAATPRTSRNNYHLAQAYLDKYYTKKGGHQVGEMVAKGGNSMVKKIKELQAFFGLRVTGKLDRTTMDVIKRPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMTPAEVDKAMEMALQAWSSAVPLSFVRVNAGEADIMISFETGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGMNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYQNPYGFHLPKDDVKGIQALYGPRKTFTGKPTVPHGPPHNPSLPDICDSSSSFDAVTMLGKELLFFRDRIFWRRQVHLMSGIRPSTITSSFPQLMSNVDAAYEVADRGMAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRYVQRIDAAVHLKDTQKTLFFVGDEYYSYDERKRKMDKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKAYKYDTEKEDVVSVLKSNSWIGC
What is the function of this protein?
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP).  May play a central role in tooth enamel formation (By similarity).
What are the official names of this protein?
Matrix metalloproteinase-20, MMP-20, Enamel metalloproteinase, Enamelysin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RS19_POLAQ
Sequence: MTRSAKKGPFCDASLVKKVEVAQANKDKKPIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYVSENMVGHKLGEFALTRTFKGHAADKKVTKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: DAPAT_CHLTA
Sequence: MKRNPHFVSLTKNYLFADLQKRVAQFRLENPQHTVINLSIGDTTQPLNASVAEAFASSIARLSSPTTCRGYGPDFGLPALRQKLSEDFYRGFVDAKEIFISDGAKVDLFRLLSFFGPNQTVAIQDPSYPAYLDIARLTGAKEIIALPCLQENAFFPEFPEDTHIDILCLCSPNNPTGTVLNKDQLRAIVHYAIEHEILILFDAAYSTFISDPSLPKSIFEIPDARFCAIEINSFSKPLGFAGIRLGWTVIPQELTYADGHFVIQDWERFLSTTFNGASIPAQEAGVAGLSILPQLEAIHYYRENSDLLRKALLATGFEVFGGEHAPYLWVKPTQANISDRDLFDFFLREYHIAITPGIGFGRSGSGFVRFSSLGKREDILAACERLQMAPALQS
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: SYI_BDEBA
Sequence: MTNANTRSTPYSAVKPDVNLAKQEETILDFWDQEKIFAQSLNPEGKKTYSFYDGPPFATGLPHYGHLLAGVLKDVVPRYWTMKGYTVPRRFGWDCHGLPVEYEINKTHKIESRKDVFKMGVANYNDACRSIVKRYSTEWKTTVRRVGRWVDMENPYFTMDVSFMQSVWWVFQQLFNKGLIYEGYKVVPYSVGISTSLSNFEANQNYKMVQDPAITVMFKLVNQPDTAIMAWTTTPWTLPSNLALAVGNDIEYVKVQEKATGRKLIMAQALLSSVFKKADEEVEVLQMMKGTELVGLTYEPLFPYFGDRADKGAFRIISSDHVTTESGTGVVHMAPAFGEEDYYACAKAGIPMVNPVDDDGMFTMEVPDYAGKRVKEADKDIIADLKKRGNLFKQDTIQHSYPFCYRSDTPLIYRAVSSWFVAVEKIKEELIANNKQTSWVPDHLRDGRFGNWLEGARDWAISRNRFWGTPLPIWRNAEGEVMCIGSRAELEKLSGQKVDDLHIEFVDKITIPSPTGKSPLKRVDGVLDCWFESGSMPYAQWGYPETSVEDFKKAFPADFIAEGLDQTRGWFYTLSIIGTALFNQAPFKNVVVNGLVLAEDGRKMSKSLKNYPDPMEVLNQHGADALRLYLIDSPVVKAQELKFSEKGVYDIVRKILLRWWNSYSFFANYANIDGFVPKGDAKKSPNILDQWVLSRLNGLIANTHKEMDAYRLYNVVPHLLQFIEDLTNTYIRFNRSLFWQDGMPETKRYAYETLHEVLVTLSRLMAPFAPFMSEVTYKNLAQVLKDKKDSVHLESFPTADLSMLRPELEEAVKAMDTLVTLGRNHREKIGVKAKIPLNEIKIIHRSAELLETLKKFEPFFVDELNFRKVVYNPNEDQFVQVTAKANFPVLGKRLGPKMKAVGAGIMSMSLENILKLEGGGVVVIEGEEISLSDVEIRRAPKGDNANLSVHQIVSIEVDPTVTPEQEREGLAREIMRKIQVARKTADFQMDDKITLEIACDGALLDALNAHKDMITGETLTKNLNILALTAEPNGKHTETSDIDGQVIKIGVTNLPR
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MKAR_ASPFU
Sequence: MEFLSKYTACLSNWGLNLEPGLQTVGAAVLLTTGTLFIASRVLTFVRVLLSLFVLPGKPLRSFGPKGSWAVVTGASDGLGKEFSLQLARAGFNIVLVSRTASKLTTLAEEITTKHSVQTKTLAMDYAANNDADYEELKAIVDGLDVAVLINNVGKSHDIPTPFALTPEDEMTDIVTINCLGTLRTTQLIIPGMMQRKRGLVLTMGSFGGLLPTPLLATYSGSKAFLQQWSTSLGSELEPYGITVELVQAYLITSAMSKVRRTSATIPDPRAFVKAVLSKIGRNGGSPGYAYSSSPYWSHGLMAWFLTCVMQPMGKLVVGQNKSMHEAIRKRALRKAEREKGKKST
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NU4C_SYNR3
Sequence: MCVKGDAQLAAAAEISTLQPDAAKELDSFPWLTTAILLPIAASLAIPLVPDPGNGKGVRWYALGVSLTTFLITVGAYLNGYDPDIAGLQLRQVIPWVPDLGLGWSVGADGLSMPLILLTSFITTLACLAAWPVTFKPRLFFFLLLAMDGGQIAVFAVQDMLLFFLAWELELIPVYLLLAIWGGKKRQYAATKFILYTAVSSLFILLVALAMAFSGGGPVSFEYSDLAAKHLGAGFQALCYAGLLIAFGVKLPIVPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALFRFNASMFPDAHVQFAPLLVVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFSPLAASGAMLQMISHGLIGASLFFLVGATYDRTHTLQLDEMGGVGQRMRKMFAMWTACSLASLALPGMSGFVSELMVFVGFATDDAYTLPFRIVIDGAAAIGVILTPIYLLSMLREIFFGQEKPELSDANLVDAEPREIYIISCLLVPIIGIGLYPKLVTDSYRATIEQVVARDESSMKALTAPYLPLRSAPKLS
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, NAD(P)H dehydrogenase I, chain 4, NDH-1, chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: LUXS_SALTI
Sequence: MPLLDSFAVDHTRMQAPAVRGAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: XYNF3_ASPFN
Sequence: MVHLKALASGTLFASLASSAVISRQAAASINDAFVAHGKKYFGTCSDQALLQNSQNEAIVRADFGQLTPENSMKWDALEPSQGSFSFAGADFLADYAKTNNKLVRGHTLVWHSQLPSWVQGITDKDTLTEVIKNHITTIMQRYKGQIYAWDVVNEIFDEDGTLRDSVFSQVLGEDFVRIAFETAREADPNAKLYINDYNLDSADYAKTKGMVSYVKKWLDAGVPIDGIVSLLPPRDEGLTSCTALTALASTGVSEVAVTELDIEGASSESYLEVVNACLDVSSCVGITVWGVSDKDSWRSSTSPLLFDSNYQAKDAYNAIIDAL
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable endo-1,4-beta-xylanase F3, Xylanase F3, 1,4-beta-D-xylan xylanohydrolase F3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PEPT1_DERMI
Sequence: TQACRINSGNVPSELDLRSLRTVTPIRMQG
What is the function of this protein?
Thiol protease that hydrolyzes proteins, with a preference for Phe or basic residues.
What are the official names of this protein?
Peptidase 1, Allergen Der m I, Major mite fecal allergen Der m 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Secreted.