PharMolix/UniProtQA huggingface dataset:
Protein: MUCR_RHIME
Sequence: MTETSLGTSNELLVELTAEIVAAYVSNHVVPVAELPTLIADVHSALNNTTAPAPVVVPVEKPKPAVSVRKSVQDDQITCLECGGTFKSLKRHLMTHHNLSPEEYRDKWDLPADYPMVAPAYAEARSRLAKEMGLGQRRKRRGK
What is the function of this protein?
Regulator of exopolysaccharide synthesis.  Represses the activation of EPS II (exp) genes for galactoglucan and activates the EPS I (exo) genes for succinoglycan.  Also negatively regulates its own transcription.
What are the official names of this protein?
Transcriptional regulatory protein MucR.
What is the protein family that this protein belongs to?
Belongs to the ros/MucR family.
Protein: ELCX_PHANO
Sequence: MALMIEKLAPPSKRSMTKFTQHCTGNCGQFWPKTWFWSRSSFIHWRLVSRHWPLAPFQLPKTTMAYALVNTKLSALRDIGN
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of elsinochrome C, a perelyenequinone phytotoxin structurally similar to cercosporin (PubMed:28251756, PubMed:30809363).  The first step of elsinochrome C biosynthesis is performed by the polyketide synthase elcA which catalyzes the formation of nor-toralactone (PubMed:28251756, PubMed:30809363).  The starter unit acyltransferase (SAT) domain of elcA initiates polyketide extension by the selective utilization of acetyl-CoA, which is elongated to the heptaketide in the beta-ketoacyl synthase (KS) domain by successive condensations with six malonyl units introduced by the malonyl acyltransferase (MAT) domain (By similarity).  The product template (PT) domain catalyzes C4-C9 and C2-C11 aldol cyclizations and dehydrations to a trihydroxynaphthalene, which is thought to be delivered to the thioesterase (TE) domain for product release (By similarity).  The bifunctional enzyme elcB then methylates nor-toralactone to toralactone before conducting an unusual oxidative aromatic ring opening (PubMed:28251756, PubMed:30809363).  The next step in perylenequinone biosynthesis is an O-methylation at the nascent OH-6 of the elcB product performed by the O-methyltransferase elcD (PubMed:30809363).  The oxidative coupling of the two monomeric naphthol units in perylenequinone biosynthesis is catalyzed by the FAD-dependent monooxygenase elcE and the multicopper oxidase elcG (PubMed:30809363).  ElcG might catalyze the first intermolecular coupling in a regio- and stereo-selective manner via a phenol radical coupling mechanism and the elcE could forge the second C-C bond intramolecularly via a hydride transfer mechanism (PubMed:30809363).  The fasciclin domain-containing protein elcF might also play a role duting this step (Probable).  The last piece of the puzzle in the biosynthesis of elsinochrome C is the additional annulation by enolate coupling to afford the dihydrobenzo(ghi)perylenequinone system, catalyzed by the FAD-dependent monooxygenase elcH (PubMed:30809363).
What are the official names of this protein?
Elsinochrome C biosynthesis cluster protein SNOG_08613.
Protein: RIMP_STAAE
Sequence: MSKITEQVEVIVKPIMEDLNFELVDVEYVKEGRDHFLRISIDKEGGVDLNDCTLASEKISEAMDANDPIPEMYYLDVASPGAERPIKKEQDFQNAITKPVFVSLYVPIEGEKEWLGILQEVNNETIVVQVKIKARTKDIEIPRDKIAKARHAVMI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAP_PSEAE
Sequence: MLDLVAAFIALTTLLTYVNYRFIRLPPTIGVMATALVFSLIVQGLSELGYPILEVEMQEIIRRIDFSEVLMTWFLPALLFAGALHVDLSDLRSYKWPIGLLATAGVLIATFVIGGLAYYTFPLFGWQVDFIYCLLFGALISPTDPIAVLGILKSAGAPKPLATTIVGESLFNDGTAVVVFAIILGILQLGEAPTVSATAILFVQEAIGGVVFGAVLGYGVFVMMRGIDQYQVEVMLTLALVIGGAALAARLHVSAPIAMVVAGLIIGNHGRHYAMSDETRRYVDKFWELIDEILNALLFALIGLELLLLPFSWLHVAAAFALGGAVLVSRLLTVGPAILVLRRFRGANRQVPAGTIRILVWGGLRGGVSVALALSLPLGPERDLILSLTYIVVLVSILLQGLSIGPLVRRIYAGQPLEKSEGAH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.  Has also weak Li(+)/H(+) antiport activity.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaP, Sodium/proton antiporter NhaP.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WEE2_PIG
Sequence: MGDNGDNKELKQKLNFSYSEEEQEDEGQKEAQESKKVQYHTPERCGHQDSEAKFTPPRTPLNHVCELSTPQVKDRASPDQGLRTPVSRPHTRPETPAPPDKSKPPPHCESPFTPRGHSSQSVISTGKLPSRGSKHLRLTPGPLTDEMTSLALVNINPFTPESYRRQFLKSNGKRKTRRDLEEAGPEEGKVEKGLPAKRCVLRETNMACRYEKEFLEVEKIGVGEFGTVYKCIKRLDGCVYAIKRSTKPVSGLSDENLAMHEVYAHSVLGHHPHVVRYYSSWAEDDHMMIQNEYCNGGSLQAAISENAKSGNHFQEPKLKDILLQISLGLKYIHNYGMVHMDIKPSNIFICHKIPSDSPVVPEEAENEADWFLSANVTYKIGDLGHVTSISEPQVEEGDSRFLAKEILQENYQHLPKADIFALGLTIAVAAGAEALPTNGTSWHHIREGQLPNIPQDLSKEFYNLLKDMIDPDPVARPSAAALTRSRVLCPSLGRTEELQQQLNLEKFKTATLERELKEVQRAQSSKEGQSSPGVTGTHTGSRSTRRLVGGKSAKSSSFTWGQSSP
What is the function of this protein?
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II.  Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry.  Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation.
What are the official names of this protein?
Wee1-like protein kinase 2, Wee1-like protein kinase 1B, Wee1B kinase, pWee1B, pigWee1B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RM33_DICDI
Sequence: MGTPIKKISTVIIKMVSSANTGYFYRTTKSALLSTKKLLLRKYDPVIRQHVLFKEEKISRKKN
What are the official names of this protein?
Probable 39S ribosomal protein L33, mitochondrial, L33mt, MRP-L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACYP_CUPPJ
Sequence: METWHMTAHGRVQGVGYRAGCAQAAIALGVRGWVRNRADGTVEVMASGTIQQLEALRNWMQAGPPAAHVARVDVEPGQGKFEDFDLRPTL
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: SX25_LEIHE
Sequence: MKLLLLLIVSASMLIESLVNADGYIKRRDGCKVACLVGNEGCDKECKAYGGSYGYCWTWGLACWCEGLPDDKTWKSETNTCGGKK
What is the function of this protein?
Depressant insect toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently to sodium channels (Nav) and block action potentials, primarily by depolarizing the axonal membrane and suppressing the sodium current (By similarity).
What are the official names of this protein?
Insect toxin 2-53, LqhIT2-53.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPD_PROMA
Sequence: MPIVSWPELLEKLLSTKEISEIEAKALMKAWLNDELLPVQTGAFLTALRAKQISGLELSSMAEVLRDACLFPYPLPEVFMVDTCGTGGDGADTFNISTAVAFVTASCGVTIAKHGNRSASGKVGSADVLEGLGIKLNAPLELVVKAIEKNNITFLFAPAWHSSLINLAPLRKALGVRTVFNLLGPLVNPFRPKAQVLGVAKSELLDPMVEALRNLGLERAVVVHGAGGLDEASLEGPNEVRFLENGQITSKTLDVEELGLTISPNSTLKGGSLATNQDILRSLFQGRGTQSQREVVALNSSLVFWASGKELDLKKGVTIALEAMELSKPLDKFNELKCCLE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: UPP_PECAS
Sequence: MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEATADLATEKVTIDGWCGPVEVDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGIYRDEETLEPVPYFQKLVSNIEERMALVVDPMLATGGSMIATIDLLKKAGCHSIKVLVLVAAPEGIAALEKAHPDVELYTASIDKGLNEQGYIMPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: GLRXA_LEGPH
Sequence: MLYMKGTPKMPQCGFSARAVQCIEACGVDFAYVDILANPDIRQVLPQFSDWPTFPQLYVKGELIGGSDIIAEMFQQGELEPMLRDAVAA
What are the official names of this protein?
Probable monothiol glutaredoxin GrlA.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. Monothiol subfamily.
Protein: TGAL4_ORYSJ
Sequence: MGEASSSSGHPRQNPHVLGYGFHGAMPNSLPSANLFEQQGGANYFGELEEALMQQVATLRRTQQTATTTSTLHHGDTTPFSTTATAAATARPPPTLDIFPSWPMRSLHTPKEGSNVTADTTDSESSSKNNSNQNASSDQHVLVGDMAGQFDQIPQQEQHKKMATNSPTHSSKTGKALDPKTMRRLAQNREAARKSRLRKKAYIQQLESSKLKLAQMEQDIHRARSQGLLLGAPGGNTSSGAAMFDVDYARWLEEDSQRMAELHGGLHAHLPDSDLRAIVDDTLTHYDHLFNLKGMAAKADVFHLITGMWATPAERCFLWMGGFRPSELLKTLTPQLDPLTEQQVVGICNLQQSSQQAEEALSQGLDQLHQSLAETVAGGSPLDDPNVGSFMGHMAIALGQLSNLEGFVIQADNLRQQTIHQMHRILTVRQAARCFLAIGEYHNRLRALSSLWASRPREILVADEGNCGELSIAAHPSESQYSAF
What is the function of this protein?
Transcriptional regulator involved in defense response.
What are the official names of this protein?
Transcription factor TGAL4, bZIP transcription factor 79, OsbZIP79.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPD_FRATF
Sequence: MTNISVIAKPYAKAAFEFANEHNLLQQWSKLLQTFSELIKDKSVAAIVSSPTISQIEVVDALKKQLDENFFNFLALIAENKKMLIMPEIADQFESIKNIHNNVRVADVTLAYATDKNILDSLKTSLEKKFGCTIDMHINIDPAIIGGAVVKVGDTVIDSSVSGHLEKLKSILLS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CDC26_MOUSE
Sequence: MLRRKPTRLELKLDDIEEFESIRKDLEARKKQKEDVEGVGTSDGEGAAGLSSDPKSREQMINDRIGYKPQLKSNNRTSQFGNFEF
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit CDC26, Cell division cycle protein 26 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC26 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDHI_PARHY
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTIFNLPERKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HLDD_SALG2
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMSGEELGDIEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVAAVNLWFLESGKSGIFNLGTGRAESFQAVADATLAYHKKSSIEYIPFPDKLKGRYQAFTQADLTNLRNAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: NUOB_AZOPC
Sequence: MKTEDFRDNEYLEEYLKELWGNGANIAIAKLNDLINWGRSNSVWPLTFATSCCGIEFMCLGAARYDFARFGWEVTRNSPRQADVVFCCGTIVHKMAPVLKRLYDQMSEPKYVIALGSCAISGGPFKSSYHTIMGIDKIIPVDVYIPGCPPRPDAMIYGMIQLARKIKVQNFFKLPNLSHIEGNSLKKGERQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NPR8_CAEEL
Sequence: MEVKDIDNYCDRGISPNASNYLTYPFDGLCLQKFFYQLQTSLRRFTPYEEIIYTTVYIIISVAAVIGNGLVIMAVVRKKTMRTNRNVLILNLALSNLILAITNIPFLWLPSIDFEFPYSRFFCKFANVLPGSNIYCSTLTISVMAIDRYYSVKKLKIASNRKQCFHAVLVSLAIWIVSFILSLPLLLYYETSMLYVMREIRVVDQSGQEVIRSYGWRQCRLVSAGRLPDITQSIQLLMSILQVAFLYIVPLFVLSIFNVKLTRFLKTNANKMSKTRAPPKRFDRSDSHHNSLKNNNNHTSSLRSPSMPSIRSSITERNKTNQRTNRTTSLLIAMAGSYAALWFPFTLITFLIDFELIINQDYVNLVERIDQTCKMVSMLSICVNPFLYGFLNTNFRHEFSDIYYRYIRCETKSQPAGRFHHDVSSIAHHRQDSVYNDEATLLTTGRQSNGKDGSSSPIGFRSSVRVCSGQTKMIGDRIVLDDDIEKDSFV
What is the function of this protein?
Not known.  Putative receptor.
What are the official names of this protein?
Probable G-protein coupled receptor npr-8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PG076_VAR67
Sequence: MLVVIMFFIAFAFCSWLSYSYLRPYISTKELNKSRMFYIT
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex protein OPG076, EFC protein OPG076, Protein O3.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG076 family.
Protein: OPPA_SALTY
Sequence: MSNITKKSLIAAGILTALIAASAATAADVPAGVQLADKQTLVRNNGSEVQSLDPHKIEGVPESNVSRDLFEGLLISDVEGHPSPGVAEKWENKDFKVWTFHLRENAKWSDGTPVTAHDFVYSWQRLADPNTASPYASYLQYGHIANIDDIIAGKKPATDLGVKALDDHTFEVTLSEPVPYFYKLLVHPSVSPVPKSAVEKFGDKWTQPANIVTNGAYKLKNWVVNERIVLERNPQYWDNAKTVINQVTYLPISSEVTDVNRYRSGEIDMTYNNMPIELFQKLKKEIPNEVRVDPYLCTYYYEINNQKAPFNDVRVRTALKLALDRDIIVNKVKNQGDLPAYSYTPPYTDGAKLVEPEWFKWSQQKRNEEAKKLLAEAGFTADKPLTFDLLYNTSDLHKKLAIAVASIWKKNLGVNVNLENQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSDSSNNTAHYKSPAFDKLIADTLKVADDTQRSELYAKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNIYVKNLYIIKH
What is the function of this protein?
This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
What are the official names of this protein?
Periplasmic oligopeptide-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FFAR2_HUMAN
Sequence: MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
What is the function of this protein?
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity.  In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers.  SCFAs serve as a source of energy but also act as signaling molecules.  That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301).  Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation.  May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine.  May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake.  Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes.  In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines.  May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils.  In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).  Among SCFAs, the fatty acids containing less than 6 carbons, the most potent activators are probably acetate, propionate and butyrate (PubMed:12496283, PubMed:12711604).  Exhibits a SCFA-independent constitutive G protein-coupled receptor activity (PubMed:23066016).
What are the official names of this protein?
Free fatty acid receptor 2, G-protein coupled receptor 43.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ABA2_NICPL
Sequence: MYSTVFYTSVHPSTSAFSRKQLPLLISKDFPTELYHSLPCSRSLENGQIKKVKGVVKATIAEAPATIPPTDLKKVPQKKLKVLVAGGGIGGLVFALAAKKRGFDVLVFERDLSAIRGEGQYRGPIQIQSNALAALEAIDMDVAEDIMNAGCITGQRINGLVDGVSGNWYCKFDTFTPAVERGLPVTRVISRMTLQQNLARAVGEDIIMNESNVVNFEDDGEKVTVTLEDGQQYTGDLLVGADGIRSKVRTNLFGPSDVTYSGYTCYTGIADFVPADIETVGYRVFLGHKQYFVSSDVGGGKMQWYAFHNEPAGGVDDPNGKKARLLKIFEGWCDNVIDLLVATDEDAILRRDIYDRPPTFSWGKGRVTLLGDSVHAMQPNLGQGGCMAIEDSYQLALELDKALSRSAESGTPVDIISSLRSYESSRKLRVGVIHGLARMAAIMASTYKAYLGVGLGPLSFLTKFRIPHPGRVGGRFFIDLGMPLMLSWVLGGNGEKLEGRIQHCRLSEKANDQLRNWFEDDDALERATDAEWLLLPAGNSNAALETLVLSRDENMPCNIGSVSHANIPGKSVVIPLPQVSEMHARISYKGGAFFVTDLRSEHGTWITDNEGRRYRASPNFPTRFHPSDIIEFGSDKKAAFRVKVMKFPPKTAAKEERQAVGAA
What is the function of this protein?
Converts zeaxanthin into antheraxanthin and subsequently violaxanthin.  Involved in the epoxidation of zeaxanthin.  Plays an important role in resistance to stresses, seed development and dormancy.
What are the official names of this protein?
Zeaxanthin epoxidase, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Peripheral membrane protein. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: US03_CHV9D
Sequence: MNYDDDCLYEDKHMDTDIYDMLADEDTSDVDNTLAVCATARAGIEKAGFSVLETFTPGAEGFTFACIENKTRENVVIKAGQRGGTVTEAHILRNINHPVIIRLMGTFTYNSFTCLVLPRYKTDLYCYLSDRRRIAICDMLSIERSVLRAIQYLHENRIIHRDVKAENIFINHPGDVCLGDFGAACYPVDITQNKYYGWAGTIATNAPELLARDPYGPAVDIWSAGIVLFEMATCHDSLFEKDGLDGDCDSDRQIKLIIRRTGVHPSEFPIDAQATLDEIYRTCQKTSRKPGTRPTWTNLYELPLELEYLICKMLAFDAHKRPSAKALLDFAAFYDIPDPYPNPTN
What is the function of this protein?
Multifunctional serine/threonine kinase that plays a role in several processes including egress of virus particles from the nucleus, modulation of the actin cytoskeleton and inhibition of apoptosis.  Phosphorylates UL31 and UL34 homologs, two critical regulators of capsid budding from nucleus to endoplasmic reticulum, thereby facilitating virion egress.  Modulates and redistributes host components of the nuclear envelope, including LMNA, emerin/EMD and the nuclear matrix protein MATR3.  Phosphorylates envelope glycoprotein B (gB), probably to direct it to the cell surface.  Promotes virus intracellular spread by restructuring host cell cytoskeleton.  Blocks host apoptosis to extend cell survival and allow efficient viral replication.  Promotes viral gene expression by phosphorylating host HDAC2 to reduce viral genome silencing (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase US3 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: AMPA_SALEP
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMRELGMNAYLAVGHGSQNESLMSVIEYKGNPSEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMSNHNPLAHELIGASEQAGDRAWRLPLGDEFQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLSQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.