PharMolix/UniProtQA huggingface dataset:
Protein: RK23_JASNU
Sequence: MDGIKYAVFTEKSIRLLGKNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKGRRMGPIMGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BIOH_PECAS
Sequence: MAALYWQTEGAGNTDLVLLHGWGLNAQVWQSMVVRLAPHFRLHLVDLPGYGRSQGFGPMPLNDMANIVLTQAPERAVWLGWSLGGLVASQIALSAPLRVEKLITVASSPCFSAQDDWPGIKPDVLQGFQQQLSEDFQRTVERFLALQTLGTENARQDARLLKGVVLEQPMPSVDVLNGGLEILREADLRQPLADLTVPLLRLYGALDGLVPRKVAGRLDDEWPNSTSVVMPKAAHAPFISHPDAFTEQVIAFAQA
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTBS_DROME
Sequence: MNPLKILIWNANGISRKAKDVELFAHNKKVDILLVTELRLKRGETVKIYGYAYYPAYRPSLNNNSVGGVAVFVRTTLRHFPQRVIETRHIQLSSVKVATGLGDLQFSAIYCSPSTRIEERHFTDIIRACGQRYLVGGDWNARHWLWGDTCNSPRGRELAEALSVTGAKILATGSPTRYPYVPSHTPSCIDFAVYHGIPDHLATITQSWDLDSDHLPLIISIETDSTHVNPSPRLVTKHTDLLAFSRQLESLISLNTTLNSGEEIEMAVDNLTESIHRAAAVSTSPVPRIGTTYGIVLTREARELLTQKRRLRRRAIRSQDPWDRLLWNRAAKQLRNVLRELRSNFFEQKLASMDYTVDAGYSLWKCTKSLKRQPFRQVPIRCPGGELAKNEEEQANCFANHLETRFTHFQFATTEQYQETLDSLETPLQMSLPIKPIRVEEIVEAIKSLPLKKSPGIDNVCNATLKALPVRAILYLALIYNAILRVQFFPKQWKMAAILMIHKPGKPEESPESYRPISLLSSLSKLWERLIANRLNDIMTERRILPDHQFGFRQGHSTVEQVHRLTKHILQAFDDKEYCNAVFIDMQQAFDRVWHDGLISKVKKLFPAPYYGVLKSYLEDRRFMVRVRNSYSIPRVMRAGVPQGSVLGPLLYSVFTADLPCPNAYHMADPRKALLATYADDIALLYSSNCCNEAARGLQEYLTTLAAWCKRWILKVNPQKTINPCFTLKTLSPVTAPIELEGVILDQPSQAKYLGITLDKRLTFGPHLKATTRRCYQRMQQLRWLLNRKSTMTLRAKRAVYVHCVAPIWLYGIQIWGIAAKSNYNRIQVLQNRAMRAITDCPYYVRGTTLHRDLNLHTVEEQISRHTSRYSDRLRRHHSILARRLLPARPLRRLKRKGFAKTLGQP
What are the official names of this protein?
Probable RNA-directed DNA polymerase from transposon BS, Reverse transcriptase.
Protein: BSSE_THAAR
Sequence: MKNSGLLNSVHVPAADPYYYLNTETLSLLNRIQRISQKHPVNVLVIGKQGCGKSSLVRQYAAVHHLPLATFQIGLLSEPGQLFGEYALENGETRYKQFLFPQAIQTPGCVIHLEEINRPEHPKALNMLFSILSDDRQVWMDELGLLKVADGVVFFATLNEGDEFVGTELLDPALRDRFYVTAMDFLPNDVEREVLQKKTGVTIAQAEEIIGVVNSLRASPELGVEVSTRKTLMIGEMIAAGGSLREAIAASLQTDRETLESVLLSLHVELGKTERGTTEYVLFTPR
What is the function of this protein?
May have a role in assembly and/or activation of benzylsuccinate synthase.
What are the official names of this protein?
Putative chaperone BssE.
What is the protein family that this protein belongs to?
Belongs to the CbbQ/NirQ/NorQ/GpvN family.
Protein: GLMS_BORBR
Sequence: MCGIVGAVAQRDITPILIEGLKRLEYRGYDSCGVALYMDGHLRRTRSTKRVAELSEQVAEDKLGGFTGIAHTRWATHGIPATYNAHPHFSAQGKDEPRIALVHNGIIENHEELRQELQGVGYVFESQTDTEVIAHLVNHLYAGDLFEAVQQAVRRLQGAYAIAVFCRDEPHRVVGARQGSPLVVGLGQNENFLASDALALAGTTDQIIYLEDGDVVDLQLARVWIVDQAGKQVERKAHTVQVHTGAAELGPYRHFMQKEIFEQPRAVGDTLQDIESITPELFGDGAYKVFKEIDSLLILACGTSYYAGLTAKYWIESIARIPVAVEIASEYRYRDSVPNPNALVVTISQSGETADTLAALKHARSLGMQHTLTVCNVATSAMVRECELAYITRAGVEIGVASTKAFTTQLTALFLLTLALAQTRGRLTEEQEAEHLKALRHLPAAIGAVLALEPQIMAWADRFASKENALFLGRGMHYPIALEGALKLKEISYIHAEAYPAGELKHGPLALVTEHMPVVTIAPKDALLEKLKSNMQEVRARGGELYVFADADSKIANAEGMHVIRMPEYYGALSPIVHTIPLQLLSYHTACVRGTDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUCI_SALG2
Sequence: MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALITEKMHHACGAQVECVIADTCIAGMAESAACEEKFSSQNVGVTITVTPCWCYGSETIDMDPMRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSVGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYYEAELEMALAWADKNFRYGEDQNASQYKRNEAQNRAVLKESLLMAMCIRDMMQGNKTLADKGLVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEALLNSSFDWNGVREPFVVATENDSLNGVAMLFGHQLTGTAQIFADVRTYWSPEAVERVTGQALSGLAEHGIIHLINSGSAALDGACKQRDSEGKPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKAMHDQLDARTNSTWPTTCFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLAAMLRIPVCMHNVEEAKIYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FNDC4_HUMAN
Sequence: MPSGCHSSPPSGLRGDMASLVPLSPYLSPTVLLLVSCDLGFVRADRPPSPVNVTVTHLRANSATVSWDVPEGNIVIGYSISQQRQNGPGQRVIREVNTTTRACALWGLAEDSDYTVQVRSIGLRGESPPGPRVHFRTLKGSDRLPSNSSSPGDITVEGLDGERPLQTGEVVIIVVVLLMWAAVIGLFCRQYDIIKDNDSNNNPKEKGKGPEQSPQGRPVGTRQKKSPSINTIDV
What is the function of this protein?
Acts as an anti-inflammatory factor in the intestine and colon.  Binds to and acts on macrophages to down-regulate pro-inflammatory gene expression.  Affects key macrophage functions, including phagocytosis, by down-regulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling.  May be required to dampen the immunological response in colitis.
What are the official names of this protein?
Fibronectin type III domain-containing protein 4, Fibronectin type III repeat-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Secreted. Note=The N-terminus is probably cleaved to release a secreted extracellular portion of the protein.
Protein: GAL1_ACTPJ
Sequence: MKPQQLATQKFSEHYGYSAAQTVFAPGRVNIIGEHTDYNDGFVMPCAINYGMAVSFSKRDDSVWRVYAIDIDEQDEFDLSRPIEPSEHKWANYVRGVVKYIQEKCPEFKQGADLAMTSDVPMSSGLSSSAALEISIGKTAQVLGDLPLSLAEIALIGQQAENKFVGANCGNMDQLTSALGQKDQVIMIDCRSLEITPTPVPHGYSIAIINSNVKHDLVTGEYNSRRQECEFAAKFFGVKALRDVTPAQFIERAAELQAENELAYKRAKHIISENQRVLEAVEALQAKDMVKLGQLMAGSHDSMRDDFEITIPEIDYLVELAQVAIGKNGGARMTGGGFGGCIVCLVPDEKVEHLRRIIADNYEKQTGIKETFHLCTACDGVHLI
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_RICCN
Sequence: MQKRVRNRLITIIICFCSACLGISIILYNLEKNIVFFLPPSKINEIEQGQELRVGGLVKTDSINKIADDKISFVITDNIKDCEILYQGALPALFRKGQGIIAIGQLSNGKFIARQLLAKHDENYRPPQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: GSA1_BACC0
Sequence: MVVKFTKSEALHKEALEHIVGGVNSPSRSFKAVGGGAPIAMERGKGAYFWDVDGNKYIDYLAAYGPIITGHAHPHITKAITTAAENGVLYGTPTALEVKFAKMLKEAMPALDKVRFVNSGTEAVMTTIRVARAYTGRTKIMKFAGCYHGHSDLVLVAAGSGPSTLGTPDSAGVPQSIAQEVITVPFNNVETLKEALDKWGHEVAAILVEPIVGNFGIVEPKPGFLEKVNELVHEAGALVIYDEVITAFRFMYGGAQDLLGVTPDLTALGKVIGGGLPIGAYGGKKEIMEQVAPLGPAYQAGTMAGNPASMASGIACLEVLQQEGLYEKLDELGAMLEKGILEQAAKHNIDITLNRLKGALTVYFTTNTIEDYDAAQDTDGEMFGNFFKLMLQEGVNLAPSKYEAWFLTTEHTKEDIEYTIEAVGRAFAALADNK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LALBA_MACGI
Sequence: IDYRKCQASQILKEHGMDKVIPLPELVCTMFHISGLSPQAEV
What is the function of this protein?
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme.  This enables LS to synthesize lactose, the major carbohydrate component of milk.  In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
What are the official names of this protein?
Alpha-lactalbumin I, Lactose synthase B protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TOLB_RICTY
Sequence: MRNIVYFILTLFSLTGYALETINIEHGRVDPTPIAVNKFNADSSNNDLVGNAVVKVISNDLKISGLFRPISSASFIEEQTGINYKPLFAAWRQINASLLVNGEVQTLESGKLKISFILWDTFLEKQLIGALFEVPTKLWRRAAHKIADKIYEKITGDPGYFDTKIVYVSESTALPKIKRIALMDYDGANNKYLTNGKSLVLTPRFAHSADKIFYVSYATKSRALVYEKDLKTGKESVVGDFVGISFAPRFSPDGKKAVMSIAKNGSTHIYEIDLATKQLNKLTDGFGINTSPSYSPDGKKIVYNSDKNGVPQLYIMNSDGSDVRRISFGGGSYASPSWSPRGDYIAFTKITRHDGEKIFNIGIMKAYPQDHENSERIITSGYLVESPCWSPNGRVIMFSKGWPSRAKAPGKNKIFTIDLTGHNEREVITPAGASDPEWSDVLN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VPS4_ARATH
Sequence: MYSNFKEQAIEYVKQAVHEDNAGNYNKAFPLYMNALEYFKTHLKYEKNPKIREAITQKFTEYLRRAEEIRAVLDEGGSGPGSNGDAAVATRPKTKPKDGEGGGKDGEDPEQSKLRAGLNSAIVREKPNIKWSDVAGLESAKQALQEAVILPVKFPQFFTGKRRPWRAFLLYGPPGTGKSYLAKAVATEADSTFFSVSSSDLVSKWMGESEKLVSNLFEMARESAPSIIFVDEIDSLCGTRGEGNESEASRRIKTELLVQMQGVGHNDEKVLVLAATNTPYALDQAIRRRFDKRIYIPLPEAKARQHMFKVHLGDTPHNLTEPDFEYLGQKTEGFSGSDVSVCVKDVLFEPVRKTQDAMFFFKSPDGTWMPCGPRHPGAIQTTMQDLATKGLAEKIIPPPITRTDFEKVLARQRPTVSKSDLDVHERFTQEFGEEG
What is the function of this protein?
Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole.  Required for multivesicular body (MVB) protein sorting.  Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex (PubMed:17468262, PubMed:20663085, PubMed:21810997, PubMed:22258747, PubMed:24812106).  May also regulate cell cycle (PubMed:20663085).  Required during seed development for the formation of mucilage in seed coat and testa (PubMed:20930567).  Involved in the maintenance of Na(+)/K(+) homeostasis under salt stress (PubMed:23580756).  Required for cell expansion (PubMed:24385429).
What are the official names of this protein?
Protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1, AtSKD1, Protein VACUOLAR PROTEIN SORTING 4.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Note=In young trichome vacuole-free cells, present in the cytosol and in the nucleus. In vacuole-containing cells, present in punctae and large speckles corresponding to prevacuolar compartments (PubMed:20663085). Localized in multivesicular body when associated with LIP5 (PubMed:25010425).
Protein: Y1416_HAEIN
Sequence: MPIKEPDVWALIWSWLQTNLSSSSAQSAFWALFISLLRFGFMRKKPAIRYVLIDAAMCASIAGVAVPICTHLFGHTEYSSFLGTMIGFVGTEKIREFLFKFINRRIEKDDNDDFRSDI
What are the official names of this protein?
Uncharacterized protein HI_1416.
Protein: FMT_STACT
Sequence: MSRVIFMGTPDFSTKVLEMLIAEEDVIAVVTQPDRPVGRKRVMTPPPVKEVALENGIEVYQPEKISQSDDLQTLIDMEPDLIVTAAFGQILPKSLLDAPKLGAINVHASLLPKYRGGAPIHQAIIDGEKETGVTIMYMAPKLDAGDIISQQAIEIEANDNVESMHDKLSFLGADLLKKTLPEIINGTNDRIAQDDDKATFASNISREDERIDWTQSAEQVYNHIRGLSPWPVAYTKLDDTNMKLYAARIEEGKKGNPGEILETTKKAIIVGTGSDDAIALTEIQLSGKKRMPTANFLSGYQEDLVGKELK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: C11B1_MESAU
Sequence: MALRAKADVWLARPWQCLPRTRALGTTAALAPNTLRPFEAIPQYSRNRWLKMLQILREEGQEGLHLEMHEAFRELGPIFRYSMGRTQVVYVMLPEVAEKVFQADSTQPSRTLLEPWVAHREHRGLSRGVFLLNGPEWRFNRLRINPHMLSPKAVQKFVPMVDMVARDFLEFLKKKVLANAHGSLSMNFYSSMFNYTIEASHFVLFGERLGLLGDDLNSGSLKFVNALNSIMKTTPQLMLLPSGLTRWISTRVWKENFDSWDFVSEYVTKNVKNVYQEVQSGGPQSWSVISQLVAEGALTMDAILANSLELTAGSVDTTSVPLVMTLFELARNPDVQQAVRQESLAAEASVAANPQRAMSDLPLLRAVLKETLRLYPVAVFLERILSSDLVLQNYHVPAGTILHMSLYSMGRNPAVFPRPEHYLPQRWLERNGSFQHLTFGFGVRQCLGKRLAQVEMLLLLHHVLKSFRVETQEREDVRMVYRFVLAPSSSPLLTFRPVS
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids.  Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11-deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule.  Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
What are the official names of this protein?
Cytochrome P450 11B1, mitochondrial, CYPXIB1, Cytochrome P450C11, Steroid 11-beta-hydroxylase, CYP11B1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: YODF_BACSU
Sequence: MQGNLTALLITAIIVLTVVCIGFLAGRDKSSRTSVEEWSVGGRRFGGLLVWFLVGADLYTAYTFLGLTSTAFTGGSVAFFAIPYSVLAYFIAYFFLPKLWKVAKIHKLTTLADYARERFNSKLLASLVAIVGVLMLIPYICLQLSGIQDTLQVAGTGYINVKFVVIISFILVALYTFFSGIKGPTYTAIIKDILVWVIMLFMVVSLPLIHFNGWTPMIDTLVKEAPQMLTIPSEGPKGIPWFITASIVSALALFMWAHAATGVFTAKSADAVRKNSMFLPLYNIVLILVIFLGFIAFLVLPEDTNPRLALLHLIQTSYGGVAQGFAYATIALASLIPCSIMAIGASNLFANNLYRDLIHPNVSQSKLTLVTRSMVFVVIGLALLFGMLFPTALVTLQLLGVSGMVQIFPAIAVSLFWKNQTKEATVIGLLAGLAVTFIVYITQSAHGIYEGFWGLAANMIAVVILNPLFVKNAGSNPVIEGLFGKKQDANPNQKGA
What are the official names of this protein?
Uncharacterized symporter YodF.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYI1_BACC1
Sequence: MEYKNTLLMPKTEFPMRGNLPKREPAMQEKWAEMNIYEKVQEHTKGRPLFVLHDGPPYANGDIHMGHALNKVLKDFIVRYKSMTGFCAPYVPGWDTHGLPIEQALTNKGVKRKEMTVAEFRKLCAEYAYEQVERQREQFKRLGVRADWDNPYITLEPAYEAQQIKVFGDMAKKGYIYKGQKPVYWSPTSESALAEAEIEYQDKKSASIYVAFPVKDGKNVLEGDEKYIIWTTTPWTLPANLGISVHPELEYAIVKVNDEKYIIASELFETVAKTLEWENAEVVKTVKGSELEYTVAKHPFYDRDSLVMLGDHVTTDAGTGCVHTAPGHGEDDFIVGKKYGLEVLCPVDDKGVLTEEAPGFEGLFYDKANKPITEKLEEVGALLKLTFITHSYPHDWRTKKPIIFRATAQWFASIEAFRKELLEAVAETKWVPAWGETRLHNMVRDRGDWCISRQRAWGVPIPVFYAENGDPIITDETINHVADLFREHGSNVWFEREAKDLLPEGFTHPGSPNGEFRKETDIMDVWFDSGSSHQAVLEERDDLQRPADLYLEGSDQYRGWFNSSLSTAVAVTGKAPYKGVLSHGFVLDGEGRKMSKSIGNIVVPKKIMDQLGGDILRLWVSSVDYQSDVRISDDILKQVAEVYRKIRNTFRFLLGNLDDFKPSENTVAVAELREVDRYMLVKLNDLITKVKEAYETYDFAAVYHAIHNFCTIDLSSFYLDFAKDILYIEGANHEDRRAIQTVLYDVLVALTKLVTPILPHTADEVWPYIPGVTEESVQLTDMPEAVQLDGAEALKTKWDAFMTLRDDVLKALEVARNEKVIGKSLNASITLYPTAEMKAMLESINEDLKQLFIVSEYKLGGMMEEAPADAPKYEHTAVVVAQATGETCERCWVVSETIGKDAEHETLCERCATVVKENYVK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase 1, Isoleucyl-tRNA synthetase 1, IleRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECOT_SHIF8
Sequence: MKTILPEVLFAAFATTSAWAAESVQPLEKIAPYPQAETGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAEVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RHAA_ECOK1
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDRIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYLGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSEWLENVRTYEKEILSRRG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O16CB_CONVX
Sequence: MKLTCVMIVAVLFLTAWTVVTAEPHSSNVLENLYLKAHHEMENPEASKLNTRDRCQRANFVCDAFHHAAVCCEGVCVLVCAW
What are the official names of this protein?
Conotoxin C11GB.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DDX55_CAEEL
Sequence: MTSKVGPVALKTFREKLGPELLEVFDKSYKSFTDVQVLSGTHLLNLSDVVVESPTGSGKTLAFVLPMMRMIQNAKLQPADIGALILSPSRELCSQIVSVIQPFAEKLNLTVETVTGGQKVDKNIKMFKNKNVNILVATPGRLFQIIQHEKTLIARKMRTLQLLVIDEADRFNEIQFEDHMREILSCIPKQRRTGLFSATQVKEEDDLMVFGLRNAKQVKVAQERNSAAPSTLKNYYVECRADEKTSVCLEFIRQRTDKKILIFFPSCNSVRYFYKIFERCLGKRPLFAVHGKCSNPHRASQIKAFSDSTNGVMISTDVMARGIDISDIDWVIQFDLPKHSSWFVHRAGRTARCGREGNALILIASEQLAYVNFLDNHEKVKLDEIKVPTNNSRKSEELRQKMIKIQVSDRAILEAGTRAFVSHVESYAKHDCHLICSLDDLNVVGLANSYALLRLPKMRELSQRKDLDMFDRSAIETSEIKYADVKLEANRETVMKEKHEKKVETLAAKDKKRREKEARKLKKMGGRFRNGGGTGRKAEEKKALKRKAEEEDDAQNDIRLLKRIKRGKLSKKEIKDVL
What is the function of this protein?
Probable ATP-binding RNA helicase.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX55 homolog, DEAD box protein 55.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
Protein: GST36_CAEEL
Sequence: MPHFKFYYFDVRGRGEAIRLLFHLADEKFDDERFGMEQWGVLKSEMPLGQVPVLEIDGVKISQTTAIARYLGHQFHRAGTNAVDCARLDMIAEVIQEFMSSSGMGKFSRVLLGMIQANKEQFFKENVLPDVEKYAPIVEKFLLENGNNGLLLGDRETWVDVFAAESFSKLIDYGSPDALDAYPHILALINRVFNHPNIKKYVSQRKATPA
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Probable glutathione S-transferase gst-36, GST class-sigma.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Sigma family.
Protein: COFE_METMP
Sequence: MIKERVKMEVIGLEIPLISGNEDYTLAELISTYPLEDKDVIVIAETVVSKIEKNVILKNEITPSNEAMELSKKLGKEPEVVQVILDESNEIVKLGPNFIITETKHGFVCANSGVDESNTSKGIKPLPKNPDKSAEEIRMGIEKITGKKVGVIINDSMGRPFRKGSCGIAIGVSGVCGLWDRKGEKDLFGRELKTTEVGIADELAATASAVMGQSNEGIPLVIIRNAPVPFTNGTGKELIRKKEEDVFR
What is the function of this protein?
Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
What are the official names of this protein?
Coenzyme F420:L-glutamate ligase, Coenzyme F420-0:L-glutamate ligase, Coenzyme F420-1:gamma-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the CofE family.
Protein: RL24_BURO0
Sequence: MNKIRKGDEVIVVTGKDKGKRGVVLAVGAEHVTVEGINLVKKHVKPNPMKGTTGGVEAKTMPLHISNVALVDANGKASRVGIKVEEGKKVRFLKTTGAVLSA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: AERA_AERSA
Sequence: MMNRIITANLANLASSLMLAQVLGWHEPVYPDQVKWAGLGTGVCASGYRPLTRDEAMSIKGNLVSRMGQWQITGLADRWVIMGPGYNGEIKQGTAGETWCYPNSPVSGEIPTLSDWNIPAGDEVDVQWRLVHDNDYFIKPVSYLAHYLGYAWVGGNHSPYVGEDMDVTRVGDGWLIKGNNDGGCSGYRCGEKSSIKVSNFSYTLEPDSFSHGQVTESGKQLVKTITANATNYTDLPQQVVVTLKYDKATNWSKTDTYSLSEKVTTKNKFQWPLVGETELAIEIAASQSWASQKGGSTTETVSVEARPTVPPHSSLPVRVALYKSNISYPYEFKAEVNYDLTMKGFLRWGGNAWYTHPDNRPTWEHTFRLGPFRGQGEQHPLPVDKRYIPGEVKWWDWNWTISEYGLSTMQNNLGRVLRPIRSAVTGDFYAESQFAGDIEIGQPQTRSAKAAQLRSASAEEVALTSVDLDSEALANEGFGNVSLTIVPVQ
What is the function of this protein?
Secreted, cytolytic toxin that forms pores in host membranes after proteolytic removal of a C-terminal propeptide, leading to destruction of the membrane permeability barrier and cell death.  The pores are formed by transmembrane beta-strands and are approximately 3 nm in diameter.
What are the official names of this protein?
Aerolysin, Hemolysin-3.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Note=Secreted as a soluble precursor.