PharMolix/UniProtQA huggingface dataset:
Protein: H962L_ASFK5
Sequence: MGKPTLLEPGHLYNVPAEHKNDIPIHYIITWIKQRLPEFGGSIPTSLADRVLIIKSRTGSGKSTALPVHVFRILRNENTHSFQKYLGRSVICTQPRVLTAVTLAKDIGASTHYPDMILGQTVGYQTKPLTEKPNRGLIYATAGVLLAQLHTMTDDEIASRYAFMIIDEAHERALGIDLMLMYIKSMLERMLQRGSIGALRIPFVILTSATIDTYKYSTYFGIGKENIILVEGRQFGVETHWPLYNTNNYIKTACETALTIHKENIHDRPTEADILIFMPGMGEIRFLSMLLSHANMDLAKEKLPLMLILPIDSEAIAQENEAYLGLKAEIKDLWVKNPLTAKVEKPLRRVIVSTVVAETGLTIETLKYVIDPGWNRSVETYYPEWAGGLITRPAAQSRIEQRKGRVGRVFPGHFYPLYTKHVFEQIPAQQYPEIITEGPGAIFLNIVVETIKKNKEGVFKVQEIDMLDPPPTDALASALERAIVGGLLTRGEKGLQLTQLGDIASRFSFLSIEEARMCFSGYFWQAAISDIATILAVVSVVDKKLTNLLDSKQRNGAMLAEAVLAGIPPFLQNMDNAYSNIHLLLADDLLEGLFIFEGFQHAIIYFINNKVNNLAKHLREWCEKKMLKYSAMVQILARREDILNELAVVGLNPFHQWQNRLASANAETFLKRVCTLKQCFYEAYRLNCFCYDEQRLLYTGRNGIHFSYQDTVIKNPSCIVTPKMMLSPVSKQYMEWRLEPSFVSVLDGFVNVDINFLLPRQEIPNILGGGVEDEEEEPPLPIQAFLHKYVKTNFHFSGKSFKELKMKPHQTIKFPETTLINIIPDIPKNVVQTYLEISVCHQYSFKRLIYCETFYTDMDDVQQENSVELIGLPMAAHHLTMHDFNKLYQLLKPDGFLIVYDFHKSQEAFWLHSLQDALGHHTIRRDMDFHTISEWETIFKECGFTPMFNKQPSEHELFIVFKK
What are the official names of this protein?
Putative RNA Helicase B962L.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: PMPM_PSEAE
Sequence: MNSPALPLSRGLRIRAELKELLTLAAPIMIAQLATTAMGFVDAVMAGRASPHDLAAVALGNSIWIPMFLLMTGTLLATTAKVAQRHGAGDQPGTGPLVRQALWLALLIGPLSGAVLWWLSEPILGLMKVRPELIGPSLLYLKGIALGFPAAALYHVLRCYTNGLGRTRPSMVLGIGGLLLNIPINYALIYGHFGMPKMGGPGCGWATGSVMWFMFLGMLFWVNKASIYRASQLFSRWEWPDRATIGPLVAVGLPIGIAVFAESSIFSVIALLIGGLDENVVAGHQIALNFSALVFMIPYSLGMAVTVRVGHNLGAGLPRDARFAAGVGMAAALGYACVSASLMLLLREQIAAMYSPDPAVIAIAASLIVFSALFQFSDALQVTAAGALRGYQDTRVTMIMTLFAYWGIGLPVGYSLGLTDWFQEPTGPRGLWQGLVVGLTGAAIMLCIRLARSARRFIRQHERLQREDAEAASVLGR
What is the function of this protein?
Multidrug efflux pump that functions as an H(+)/drug antiporter.  Confers resistance to benzalkonium chloride, fluoroquinolones, ethidium bromide, acriflavine and tetraphenylphosphonium chloride.
What are the official names of this protein?
Multidrug resistance protein PmpM, H(+)/drug antiporter, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CATE_RHIME
Sequence: MAKKPSAPNNTKPATIHDQKATRGNGGELHQIAEGDTPVLTTAQGGPVADDQNSLRAGERGPTLIEDFHFREKIFHFDHERIPERVVHARGYGVHGFFETYESLAAYTRADLFQRPGERTPAFVRFSTVAGSKGSFDLARDVRGFAVKIYTKEGNWDLVGNNIPVFFIQDAIKFPDVIHSVKPEPDREFPQAQSAHDNFWDFISLTPESMHMIMWVMSDRAIPRSFRFMEGFGVHTFRFVNAKDESTFVKFHWKPKLGLQSVVWNEAVKINGADPDFHRRDMWQAIQSGNFPEWDLHVQLFDQDFADKFDFDILDPTKIIPEEVLPTKPVGRLVLDRMPENFFAETEQVAFMTQNVPPGIDFSDDPLLQGRNFSYLDTQLKRLGSPNFTHLPINAPKCPFQHFQQDGHMAMRNPVGRVNYQPNSWGEGPRESPMKGFRHFPSEEQGPKLRIRAESFADHYSQARQFFISQTPPEQRHIADALTFELSKVETPVIRERMVAHLLNIDETLGKKVGHALGLETMPKPADAAVATRQDLDPSPALSIIQRGPKRFEGRKLGILATDGADGALLDALIAAVEKEKAAFELIAPKVGGFTASDGKRIAAHQMLDGGPSVLYDAVVLLPSAEAVTDLIDVATARDFVADAFAHCKYIGYAGAAVPLLERAGIAELLDEGTIELTDAASAAAFLTEIGKLRVWGREPSVKLK
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.  Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions required for nitrogen fixation and the action of several proteins.
What are the official names of this protein?
Catalase C, KAT2.
What is the protein family that this protein belongs to?
Belongs to the catalase family. HPII subfamily.
Protein: BIOF_MAGSA
Sequence: MKGLDDSIGRFLDGLDQAGRKRVLRPVDPLPAGRVRVGGRELVNFSSNDYLGLSRHPEVVERSRRWLNEYGAGSGASRLVTGHLAAMEALEAKIARCKQTEAALILASGWQCNASVLPALLDKALWGAEPLVFADKLIHASLHAGLELSGARRYRYRHDDLDHLESLLKAHADKEGPRFIVTETVFSMDGDVTDMAALAALASRWDAFLYVDEAHATGVLGANGFGLSPGMGAELAMGTFSKGLGSFGAYVACSARLRHYLINRASGLIYATGLPPAVLGAIDAALDLVPRLEGERTRLQMMGRRLRDGLRAAGLDTGPSASQIVPLILGDEGRTLAVAKALEDRGILGIAIRPPTVPPGTSRIRFALSAVHSDADLDRLLAAILDAVEATP
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: SIT1_MOUSE
Sequence: MSRDYNCTTDDQLAWGIPSISHAWGLWALLGVVTVLLLISLAALLSQWTRGRRRNQEGQGPLSGRSAEEVPLYGNLHYLQTGRLSQEPRSEEQDPPSSGGLARGAEEAMCYTSLQLRPAQGRIPSSGNPIKYCEVVLDSEPKPQAPGPEPELYASVCAQTRRGRASFPDQAYANSQPAPS
What is the function of this protein?
Negatively regulates T-cell antigen receptor (TCR)-mediated signaling.  Involved in positive selection of T-cells.
What are the official names of this protein?
Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembrane adapter protein, Suppression-inducing transmembrane adapter 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein.
Protein: COMA1_HUMAN
Sequence: MAGLRGNAVAGLLWMLLLWSGGGGCQAQRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFPVVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP
What is the function of this protein?
Acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.
What are the official names of this protein?
Collagen alpha-1(XXII) chain.
What is the protein family that this protein belongs to?
Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Cytoplasm.
Protein: PANB_SULAC
Sequence: MSAGKVSIRDFLKKKGKEKITMLTAYDYPTAKIMSMTNLDGILVGDSLSMVVLGYENTLKVSMKEMLVHLDSVVRAKPRQLVVADMPFLSYEVSANTAVKNAGLFVRHGADSVKLEGGEEMADVVRKIVRAGIPVMGHIGLTPQRFLRIGGFRVLGKSKHEEEQLLRDAEVLEEAGIFSLVIENTYADVAKKITEKLKVPTICIGAGPYCDGQILVIHDVLGLSEFTPYFAKAYVNLKEEIQKAVNKYVEEVRESKFPQGENYKERES
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHPA_MYCTU
Sequence: MSAVVVDAVEHLVRGIVDNPDDVRVDLITSRRGRTVEVHVHPDDLGKVIGRGGRTATALRTLVAGIGGRGIRVDVVDTDQ
What is the function of this protein?
A probable RNA-binding protein.
What are the official names of this protein?
RNA-binding protein KhpA, KH-domain protein A.
What is the protein family that this protein belongs to?
Belongs to the KhpA RNA-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_STAHJ
Sequence: MKYAVIGDPVSHSLSPVMHQVNFKSLNMEDTYEALHIPTQDFHDIRHIIEDNHINGFNVTIPHKERIIPYLDEINDQAKAVGAVNTVKIINNKWIGYNTDGIGYVMGLKQVYPDLENAYVLILGAGGASKGIANELSKIVQPKLTIANRTMSRFETWDMDINAISLEQSEQYLDEFDIIINTTSAGLNNNDDIVISLDNLSSSTLVSDIIYIPYKTKFLKEAEFKGNTVYNGLDMFINQGAESFKIWTGKQPNILEMKYAVLNKLKGV
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: YCZH_BACSU
Sequence: MFPKPLVILAHEIYGVNSHMKKMGRLIKMAGYDVLTPNLLGEDEVYTLKEEKTAYEQFTKHERLKTGETIIQNVIRQNAGRHIFVIGFSVGATIAWKCSSMPEVSGSVCYYGSRIRDSLHHMPACPVLLFFPNYEPSFDVALLIKKLREKQHTHLEIYQFDALHGFANPDSVYFNRALFFKTLSIIKNGAESRLRTVSSSFF
What are the official names of this protein?
Uncharacterized protein YczH.
What is the protein family that this protein belongs to?
Belongs to the dienelactone hydrolase family.
Protein: AL4A1_BOVIN
Sequence: MLLRSAALCRALLARRGRAAGLCRRCVSSLQVANEPVLAFTQGSPERDALQKALKELKGRTEAIPCVVGDEEVWTSDVRYQASPFNHGHKVAKFCYADKALLHRAIGAALAARKEWDLKPVADRAQVFLKAADLLSGPRRAEVLAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKFAMELEGEQPLSVPPSTNSMLYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFRTFPRLAGECGGKNFHFVHRSADVDSVVSGTLRSAFEYGGQKCSACSRLYAPRSLWPQIKGRLLEELGGIKVGNPAEDFGTFFSAVIDAKSFGRIRKWLEHARSSPSLTILAGGHCDDSVGYFVEPCIVETKDPQDPIMKEEIFGPVLAVYVYPDEEYKETLRLVDSTTSYGLTGAVFAQDKDVLREATELLRHAAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYVLRWTSPQVIKETHGPLGDWRYPYMQ
What is the function of this protein?
Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate.  This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles.  The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity).
What are the official names of this protein?
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, P5C dehydrogenase, Aldehyde dehydrogenase family 4 member A1, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CRYAA_CHICK
Sequence: MDITIQHPWFKRALGPLIPSRLFDQFFGEGLLEYDLLPLFSSTISPYYRQSLFRSVLESGISEVRSDRDKFTIMLDVKHFSPEDLSVKIIDDFVEIHGKHSERQDDHGYISREFHRRYRLPANVDQSAITCSLSSDGMLTFSGPKVPSNMDPSHSERPIPVSREEKPTSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock.
Protein: GDIB_RAT
Sequence: MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPGQPPASMGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQDVIDFTGHSLALYRTDDYLDQPCCETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIKDIYKRMTGSEFDFEEMKRKKNDIYGED
What is the function of this protein?
GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins.  By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking.  Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A.
What are the official names of this protein?
Rab GDP dissociation inhibitor beta, Rab GDI beta, GDI-3, Guanosine diphosphate dissociation inhibitor 2, GDI-2.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: GATA_MYCBP
Sequence: MTDIIRSDAATLAAKIAIKEVSSTEITRACLDQIEATDETYHAFLHVAADEALAAAAAVDKQVAAGEPLPSALAGVPLALKDVFTTSDMPTTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAYGPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDSTSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAAVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRVGDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKVRTLIARDLDAAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCTLPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPLLSAI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: LPXC_TRIV2
Sequence: MKQHTLAEAIAHTGVGLHSGVSTHVRILPADAGSGRYFVRVDLPDSPIIPAQVAAVSQTVLSTQLGKGEAGVRTVEHLLAALAGMGVDNARIEIDGSEVPLLDGSAQEWVKSIAEVGLVTQAVTDNTVSWDIPEPIWIHQDDAFVAAIPASETRFSYGIDFDLPAIGNQWYSWPLTTESDTSFAKEVAPARTFGLLHQIEYLQKSGLIKGGSLDNALVCGPDGWVNPPLRFANEPVRHKILDLVGDLSLLGYFPRAHFLAYKASHNLHIQLAQRILALSN
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: LRC66_MOUSE
Sequence: MRDFYVRVTILVTGLCFVETVTTPSRKSSVSFNPEYQRNGDLLVNWSSIRHVSQNTDAMDRSFYFFRVLFQPHTQKERHIKPPDRTHHRISKVTLDPLAHLHALEILNLSNKAIHYFSLDQPLPPSSHQKRHGGHSHSRLPRLQVLILQRNQLSGTPKGLWKLKSLRSLDLSFNRIVHIGLSDFHGCLQLESIYLKSNKICTIHPKAFKGLKKLQVVDLRSNALTTLVPIVTIALELPHLELGLADNQWQCSESNVNFQNITSSSWREIWKAICNMSVENKRPNAETHQIRKSRDTHLLLSPPSDLKSLIQSKAERPQAGMDMHLSALGKEAKDGYGDLRGMWPQSPVELRDSQDEQVTDRKDDKPPALELAICLSVFITFVVAFCLGAFARPYIDRLRQQRCSNKRPGSDNAYSNKGFHGDIEGAQHMEYQGTDLHQTTHHLHLSENQNPSWVAEPIPHSAVQSEQMLGSNGTDPGHQQSPEQLKDSNESRSGDSIVLPSGPVAHLALHGLPNADAHKAISPVQHHHDFLEEAHYDTVAQEYSLIDDVMDRSSITGPLGTFPSSVESRRDDLHPSQPRDVVASFSKTLAHANTREAEGSMETGCPEPLGAMDSQMGSSEERQVSNSIRELATQQPSFQGVDAEERLSHVYSEVLHNDPPSLRPRWGSGHYVIPATGEPVERDAPFDPHYDLVTNYESDSDEGSLFTLSSEGSEDTRSLAEEQASVENDGTSQPLPSRNLGEYKDSVTSAESVEDLTSQRIPEKCEAQEAHLRNTLISGPDSCVCETNQENDSSSLDPENRSTWPQLPGHKLSHHETLGTYGDIEPQSEAVDWHYSLRDLESPNVDSSPSPPYSDEDLSGPEDRARKRSKHW
What are the official names of this protein?
Leucine-rich repeat-containing protein 66.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CT52_CONTS
Sequence: MHCLPVLVILLLLIASTPSVDARPNPKDDVPLASFHGAVNAKRYLRTLWNSRDCCDPKEPCCFIG
What are the official names of this protein?
Conotoxin TsMRCL-05.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAA_YERPA
Sequence: MTKNIHKHRILILDFGSQYTQLLARRVREIGVYCELWAWDVTEAQIREFNPSGIILSGSPESTIENGSPRAPDYVFTAGVPVLGVCYGMQTMAIQLGGKVESSNQREFGYAQVEIKADSALIRDIKDAINPAGEAVLDVWMSHGDKVAEIPADFVTVASTDTCPFAIMANEEKRFYGVQFHPEVTHTKQGLRLLERFVLGICGCEALWTSATIIEDAIVRLREQIGDDHVILGLSGGVDSSVTAMLLHRAIGKRLTCVFVDNGLLRLNEADQVLEMFGDKFGLNIVHVAAEDRFLSALTGVDEPEAKRKIIGRVFVELFDEEACKQEQVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: AROC_BUCAT
Sequence: MSGNTIGKIFCVTTFGESHGEALGCIIDGTPPGLELSCKDLQYDLNRRRPGTSRYTTLRREPDEVNILSGIFNGVTTGTSIGLIIYNHDHRSQDYSDIKNLFRPGHADYTYEKKYGIRDYRGGGRSSARETAMRVAAGAIAKKYLNEKYGITIRAYLSAMGNIKCPFKSWQEVENNPFFCSDPEKILALENLIKYLKKIGDSIGAEITIIAENIPVGLGEPVFDRLDADLSHALMSINAAKGVEIGDGFSVINQRGSEHRDEITPQGFLTNHSGGILGGISNGREIVLKVAFKPTSSIRKAGNTINKNNEKVQIVTKGRHDPCVGLRAVPITEAMVAIVLMDHLLRFRAQCSGK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RSMG_BARBK
Sequence: MVVLVEQKYQELLNMLPSVSRETMENLIQFESLIIQWNAHINLISAATVPFLWTRHILDSAQIYPLYSQCLHWCDLGSGGGFPAIVIAIFLKEKQKGHIDLIESNGKKVAFLRTVIAQLNLPATVYHCRIEDVYQKINAPEIITARGLASLNTLLQLTFPWLKQKTIALLQKGRDYAIEVENAYANWRFNLLKHQSKIDENSVILEISHVRSCQG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG122_VACCW
Sequence: MNFYRSSIISQIIKYNRRLAKSIICEDDSQIITLTAFVNQCLWCHKRVSVSAILLTTDNKILVCNRRDSFLYSEIIRTRNMFRKKRLFLNYSNYLNKQERSILSSFFSLDPATADNDRIDAIYPGGIPKRGENVPECLSREIKEEVNIDNSFVFIDTRFFIHGIIEDTIINKFFEVIFFVGRISLTSDQIIDTFKSNHEIKDLIFLDPNSGNGLQYEIAKYALDTAKLKCYGHRGCYYESLKKLTEDD
What is the function of this protein?
Decapping enzyme that remove the protective 5'-cap from both host and viral mRNAs to commit transcripts for decay by the cellular exonuclease XRN1 (PubMed:24155373, PubMed:35202449).  Preferentially targets spliced mRNAs and since all viral genes are intronless, it preferentially targets host over viral transcripts (PubMed:35202449).  Acceleration of the turnover of cellular transcripts promotes the shutoff of host protein synthesis and therefore diminish the magnitude of antiviral response (PubMed:24155373, PubMed:35435699).
What are the official names of this protein?
mRNA-decapping protein OPG122.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: COAA_CITK8
Sequence: MSKEQTLMTPYLQFDRNQWAALRDSVPMTLTEGEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKDRGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVAQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLSKDEAINTAASLWKEINWLNLKQNILPTRERASLIMTKSANHAVEQVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YUBL_YERPA
Sequence: MSEALAVLPDDTFTREQAEVVAAQYTNVAIEDDQGAHFRLVVRQNGEMVWRTWNFEPGGTYWLNRYIADYGIRKPQ
What are the official names of this protein?
UPF0401 protein YubL.
What is the protein family that this protein belongs to?
Belongs to the UPF0401 family.
Protein: Y618_METMP
Sequence: MRILLKLFVESQNLGKAINALSEGGISGFYLKEYQGMSPDDWKGFLLAEEPEMAIKIVNELSQDTVVINSIVNIECLGKIKELVRKKLENDRYTLVELPVLGMEVNSPE
What are the official names of this protein?
Uncharacterized protein MMP0618.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1244 and MJ1245 and M.thermoautotrophicum MTH1110.
Protein: CPT2_DANRE
Sequence: MMAGLLSTQCNSTLSKLKHLSNNPALSVLTSTHRKYSSKDGAGSEYLHKSIVPSMHYQKSLPRLPVPKLEDTIRRYLAAQRPLLNDEQYSNTEKLAQEFQSGAGKQLHEELVALDKKNKHTSYISAPWFDMYLSARESIVLNFNPFMSFNPDPKPEYNDQLVRATNMVCSAVRFMKTLRAGLLEPEVFHLNPAKSDTDSFKKLIRWVPPSISWFGAYMVNAYPLDMSQYFRLFNSTRIPKYKRDELLTDDRGRHLLVMKRGNLYVFDALDRDGNLIKPAEVQAHLKYILEDPTQASAFPLGVLTSENRDTWTGLRQKLLDAGNGEALQLVDTALFCLCLDEEVLRDHIHISHNMLHGDGCNRWYDKSFSVILAKDGQAAINFEHSWGDGVAVLRFQNEVFKDTTEKPLVGPGSQPASVDSSSAVRRLEFKLNDELKAGITKAKENFQAAVSKLTIDAMEFKKGGKEQLKKKKLSPDAIAQLAFQMGFLRQYGQTVATYESCSTAAFKHGRTETIRPASIHTKQCAKAFVQQPGQHSVEQLLGLLNECSKYHGQLTREAAMGQGFDRHLFAMRYLANSKGMALPSLYQDPAYAAINHNILSTSTLTSPAVSLGGFAPVVPDGFGVGYGVHDEWIGCNVSSYPARDVHEFLRCVHKSLEDIFTVLDGNPIH
What is the function of this protein?
Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites.  Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion.  Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters.
What are the official names of this protein?
Carnitine O-palmitoyltransferase 2, mitochondrial, Carnitine palmitoyltransferase II, CPT II.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL7_XANP2
Sequence: MADLTKLVDELSSLTVLEAAELAKLLEEKWGVSAAAAVAVAAAPAGAAAAAVEEQTEFTVVLAAAGEKKIEVIKEVRAITGLGLKEAKDLVEGAPKPVKEAVSKDEAEKLKAQLEKAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: UBIC_HYDCU
Sequence: MLKPSRTHLTLRHEPHWIPAGLIHRLKSPRQLHDWLLDSSSLTAKIRIGCPEMDVRILSETYEKPLISEAHHLKIPLSQKTWIRCVFLMCNGQPIVYARTVIPYWKTGNPWYALKHLGNRPLGEVLFQLPNLKRTPFQITQTHAQNWPHLDLEDSKQIKTFARKSTFIQGKYPLLLTEAFIESSL
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.