PharMolix/UniProtQA huggingface dataset:
Protein: SCC4_DROME
Sequence: MSASTSTSTAASQDACYISLLGLAEYFRTSQPPNIKKCIQCLQALFTFMPPSKVEARTHLQMGQILMAYTKNIDLARQHLEKAWSISEPLPNFDVKFDTASLLAQLHLQTDRNSHQAKAMLRRAVELSQNNVYWHCKLLLQLAQIHASDREYSLASELLAVGAESADEASATYLKVLFLLSRAMILMIERKTNDVLALLNSAGQIIDNNIPNPHQKEYLKVFFLVLQVCYYLALGQVKTVKPSLKQLQMSIQTIMAPNWPSDEAIFGANQLEMFVWLPKEQLYVLVYLVTVSHSMMAGYMDKAQKYTEKALTQIEKLKQQEDKPILSVFKVILLEHIVMCRMVMGNRELAIREIAAARDVCMAAPQRSLLRRHSAQLHCLIGLYSMSTNLFEHAERQFVVCVSETSERDLKLFANLNLAIIYLRTKRDTDLKQILDAVSTENTHTYSSQALMGGFYYVQGLHAFHKNSFHEAKRFLRETLKMANAEDLNRLTSCSLVLLSHVFLSIGNSKESMNMVTPAMQLASKIPDIHVQLWGSAILKDLHRMSKDVQHEKDAYANHVKYSENLIADQRKCVQSAHHELVNWFQGDPPVTSGPPAAPVLLMPESSVTASVPVIASTSTAMQPAGQYGQFY
What is the function of this protein?
Required for association of the cohesin complex with chromatin during interphase.  Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity).
What are the official names of this protein?
MAU2 chromatid cohesion factor homolog, Cohesin loading complex subunit SCC4 homolog, Mau2 sister chromatid cohesion factor.
What is the protein family that this protein belongs to?
Belongs to the SCC4/mau-2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Binds to chromatin from the end of mitosis until prophase.
Protein: OPSB_HUMAN
Sequence: MRKMSEEEFYLFKNISSVGPWDGPQYHIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTVSSTQVGPN
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal (Probable).  Required for the maintenance of cone outer segment organization in the ventral retina, but not essential for the maintenance of functioning cone photoreceptors (By similarity).  Involved in ensuring correct abundance and localization of retinal membrane proteins (By similarity).  May increase spectral sensitivity in dim light (By similarity).
What are the official names of this protein?
Short-wave-sensitive opsin 1, Blue cone photoreceptor pigment, Blue-sensitive opsin, BOP.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Cytoplasm, perinuclear region.
Protein: SYK_CLOAB
Sequence: MSNDEKQLTKEEMKAIKLQAKEEAKMNDLLKERRQKLSDAQERGKDPFDVYKVERTHTSKQIVDNYDELEDKIVTVAGRLMSKRVHGKAGFSDIYDRYGKIQLYLKIDDVGEEKLKEFKTFDIGDFVVITGKVFKTKTGEITLHVTKLELIAKSLKPLPEKFHGLKDPDLKYRQRYVDLIINQDVRETFMKRTAIIKAVREFLDNKDYLEVETPVLSTIASGASARPFSTHHNALDLDMHLRIATELYLKRLIVGGFEKVYEIGKDFRNEGIDVRHNPEFTMIELYEAYADYNDMMEITENMVAYACQKVNGTTKITYEGTEIDLTPPWRRVTMVDIVKEHSGIDFSTVKTDEEAREIAKEKKLELKKELKDCTKGDILNALFEEYGEKKLIQPTFVCDYPVEISPLTKKKRGNPEYTERFEGFIYGREICNAYSELNDPIVQKDRFMQQLKERELGDDEAYQMDDDFINALEIGMPPTGGMGMGMDRLVMFLTDSPSIRDVILFPTMKPTPNRD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_CAMJ8
Sequence: MKIILATSNKHKVLELKEILKDFEIYAFDEVLMPFEIEENGKTFKENALIKARAVFNALDEKQKKDFIALSDDSGICVDVLEGNPGIYSARFSDKGDDKSNRDKLVNEMIKKGFNQSRAHYVAAIAMVGLMGEFSTHGTMHGKVIDTEKGENGFGYDSLFIPKGFDKTLAQLSVDEKNNISHRFKALELAKIILKILNKG
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: FEN_METAR
Sequence: MGVDLGGLVEPREIELKELNNRTVAVDAYNTLYQFLSIIRQQDGAPLADDRGNVTSHLSGIIYRVTNLVEEGMKPVFVFDGKPPSFKAETIKARAEVREAARQMYEAAKAAGSAEAYKYAQASTSINRQIVDDAKVLLGYMGIPFIVAPSEGEAQAAYMVSRGAADYVGSQDYDSLLFGAPRVVRNIAITGKRKVPRKNIYMDVKPEVIELQEVLATLGLTREELIDMAILVGTDYNPGIFKVGPKTALKLVKKHGDNMPAILDELGQTIENWEAIKEFFLHPTVTDDYQVKWGKPEPAKIKEFLCEEHSFSVDRVDKVLERLTTAVSETTKQKTLSSWF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: NQRE_CHLT2
Sequence: MWLGDYSLLNLLGIFLQATFIQNILLSTFLGMCSYLACSSRLSTANGLGMSVALVLTITGSINWLVHYFITKPGALAWLSPALANIDLSFLELIMFIVVIAAFTQILELLLERFSRNLYLALGIFLPLIAVNCAILGGVLFGITRNYPFLPMVVFSLGSGCGWWLAIVLFATIREKLAYSDVPQHLRGTGISFITTGLMAMAFMGLTGIDISKPTTSKPAFVMNIATDSPQPNTHSSSEEPKAS
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_STRP1
Sequence: MANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANPSEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PYRF_MAGMU
Sequence: MSTSTQITKPYSTRALTHQSQTARRLLKLMSDKRTNLCASLDVTTSAELLSLADKLGPYICMVKTHVDIISDFTYDETVVKLVALAKKHGFMIFEDRKFADIGNTVKNQYSKGVYRIVEWADITNAHSVPGEGIINGLREAANEYVESEKAKGGECENLDRGLIMLAELSSKGSLATGSYTTKTVELAHNNSDFVFGFIAQNRMEEVQDSEGNYEDWLILTPGVGLDDKGDGLGQQYRTVDTVIKNGSDVIIVGRGLFGKGRDPVVEGKRYRDAGWKAYEERIN
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: AROE_HAEIE
Sequence: MDLYAVWGNPITQSKSPLIQNKLAAQTHQTMEYIAKLGNLDSFEQQLLAFFEGGAKGCNITSPFKERAYQLADEYSQRAKLAEACNTLKKLDDGKLYADNTDGIGLVTDLQRLNWLHPNQRILILGAGGATKGVLLPLLQAQQNIVLANRTFSKAKELAERFQPYGNIQAASMDSIPLQTYDVVINATSAGLSGGTAPVDAEILKLGSAFYDMQYAKGTDTPFIALCKSLGLTNVSDGFGMLVAQAAHSFHLWRGVMPDFVAVYEQLK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: AZOR1_LACPL
Sequence: MTKTLIVNAHPDFRNAAHYSVQLEQAFLQLFQTRFPNDTVDVLNLYDTVIPQATVPELLGIWEKQAQHVNLSIEEQRLFAINQQLLQQFKAHHRIVIAMPLHNFNVPARLKDYIDNILVARETFRYTENGSVGLMTDNYRVMLLQASGSIYTRNDRYTPMEFSRLYLDKMFTEIMGFDRFEIVRAQGLQTNGVAVSQALKQAKMDLKAAFERFYD
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 1, Azo-dye reductase 1, FMN-dependent NADH-azo compound oxidoreductase 1, FMN-dependent NADH-azoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RF2_AROAE
Sequence: MEAERLNAIAQQLDDLRARGRELRRYLDYDEKSSKLEEVTRALEDPAVWNNAEKAQELGKEKRQLEDVVHNLRDIESLSSDLKDLFDLAEAEDDEDTLAAVEADIGELQAKVHALEFRRMFSNPMDPNPCFIEIQAGAGGTEAQDWAGMLERMYLRYCERKGFNVELMEESEGEVAGIKGATIKVSGDYAYGFLRTETGIHRLVRKSPFDSNARRHTSFSSVFVYPEVDDSIQIDINPADLRIDTYRASGAGGQHINKTDSAVRITHEPTGVVVQCQNDRSQHKNKAEAMSMLKARLYELELRKRQSEQQKLEDSKSDIGWGHQIRSYVLDQSRIKDLRTNFEVGNTQAVLDGDLDDFIAASLKQGV
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_LACP3
Sequence: MRLVISGGGTGGHIYPALALIEALKAEGKLDDVLYVGTKRGLESRIVPATGLKFATLDLQGFKRSLSLSNFTTVRKFLGSLGEAKKLLQDFQPDIVVGTGGYVSGAILFAATRLHIPTVIHESNSVAGVTNKFLSHFVDRVAIVFPEVAKAFPANKVVVTGNPRAQQVAGLKPNDRLRDFGLDPHIRTLLAFGGSRGAPRINDAVVAALPIWAKADFQVLFATGRTHYDQIKAKLPDLPATIKVVPYIDDMPSILPDIGLLISRAGATTLAEITALGIPAVLIPSPNVTHHHQFLNAQSLTKQGAAITITEDELDNHFPRRVVTLMEDDEKRAAMAKASKKLGVPDASDQLIAVMTTLLSKRR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RK36_STAPU
Sequence: MKVRASVRKICENCRMIRRRGKVMVVCSNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CLPP1_SYNSC
Sequence: MPVSAPGPLPTVVEQSGRGDRAFDIYSRLLRERIIFLGTGVDDAVADALVAQMLFLEAEDPEKDIQIYINSPGGSVTAGLAIYDTMQQVAPDVVTICYGLAASMGAFLLSGGTKGKRLALPNARIMIHQPLGGAQGQAVDIEIQAKEILYLKETLNGLMAEHTGQPLDKISEDTDRDYFLSPAEAVEYGLIDRVVDSSGDGGIITES
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS82_RALSO
Sequence: MSLQFGPEYVRAIAPYVTGKPISEVAREFGLEAARIVKLASNENPLGMPASARVAMTAAIDGLARYPDANGFSLKAALHAKFGVPEAWITLGNGSNDILELAARALVAPGQGVIYAQHAFAVYALAAQEVGARAVEVPARDYGHDLDAMAAAITPDTRLIYVANPNNPTGTFLPADAVAAFLAKVPPTVVVVLDEAYNEFLKPEQQYDSIAWVRRYPNLLVSRTFSKAYGLAGLRVGYGIAQPQLTALLNRIRQPFNVNSLAQAAAVAALSDTEFLRRSAELNAAGYAQLTQAFARLGLEYVPSSGNFVLVRVGDDADAGARVNLALLRQGVIVRPVGNYGLPQWLRISIGLPEENAACIAALESALAQAEAAA
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SPRTL_STRP1
Sequence: MTLTNYVQEVSLADFGKPLHHKAYWNKRLKTTGGRFFPKDGHLDFNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSSKSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXL2A_XENTR
Sequence: MFDLSDQLIAMGLWSISIGAFGAAVAGILLANTDLFLTQTEEATLDYLEETELKAIGDEPKSFKAKDLWEKNGAVVMAVRRPGCFLCREEASDLSSLKSQLDQLGVPLYAVVKENIGNEVEQFQPYFNGKIFLDEKGKFYGPQKRKMMFLGLVRLGVWQNFRRAWKGGFEGNLEGEGLILGGMFVIGSGKQGILLEHREKEFGDKANLTAVLDAARKINKQRAQNDN
What is the function of this protein?
Involved in redox regulation of the cell.  Acts as an antioxidant (By similarity).
What are the official names of this protein?
Peroxiredoxin-like 2A, Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes, Protein PAMM, Redox-regulatory protein FAM213A.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin-like PRXL2 family. PRXL2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRR53_ARATH
Sequence: MSSVFGSVHILAMIAIQLLLTHSVSSLNLTNAYLHHKCSNTQGKYKQGSAFEKNLNLVLSTITSIGNFRDGFRYTEEGEDPNNVFVMFQCRGDSYWSKCPPCISTAVSGLRRRCPRNKGAIIWYDQCLLKISSVASFNKIDYENDFYLSNPNNMSDRGLFNKETSALLEKLAYKASDRNNLDGKQLVLYAAGEKRIGTKKVYAMVQCTKDLIFTKCFECLEGILRKFPQCCDGKRGGRVFGTSCNFRYELYPFLRN
What are the official names of this protein?
Cysteine-rich repeat secretory protein 53.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBP45_NICPL
Sequence: MMPQSGVAQPPMAPMSMDQHQYQQQAPPPTQQQQWMMPPQQPQQPQFQPQSQPAWAQQPSQQQYGAMATTNPNPSPTGNPNEVRSLWIGDLQYWMDENYLSTCFYHTGELVSAKVIRNKQTGQSEGYGFLEFRSHAAAETILQTYNGTLMPNVEQNFRMNWASLGAGERRDDSAEHTIFVGDLAADVTDYILQETFKSVYSSVRGAKVVTDRITGRSKGYGFVKFADESEQLRAMTEMNGVLCSTRPMRIGPAANKKPVGTPQKATYQNPQATQGESDPNNTTIFVGGLDPTVAEEHLRQVFSPYGELVHVKIVAGKRCGFVQFGTRASAEQALSSLNGTQLGGQSIRLSWGRSPSSKQTDQTQWGGSGGAYYGYGQGYEAYGYAPPAQDPNMYYGNYPGYANYQQPQQ
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation.
What are the official names of this protein?
Polyadenylate-binding protein RBP45, Poly(A)-binding protein RBP45, RNA-binding protein 45, NplRBP45.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding RBP45 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL27_PARD8
Sequence: MAHKKGVGSSKNGRESQSKRLGVKLFGGEVAKAGNIIVRQRGTVHHPGENVGIGKDHTLYALVDGVVTFRRGKENRSFVSVKEVVAEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SYW_PASMU
Sequence: MSKPVVLSGVQPSGELTIGNYLGALRQWVKMQDDYECLFCIVDLHAITVRQDPESLRKATLDVLALYLACGIDPEKSTIFIQSHVPEHTQLAWVLNCYTYFGEMGRMTQFKDKSARHAENINVGLFTYPVLMAADILLYQANQVPVGEDQKQHLEITRDIANRFNALYGDLFAVPEPFIPKAGARVMSLLEPEKKMSKSDENRNNVIGLLEDPKAVAKKIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSGVTGKSIAELETEFEGKMYGHLKGTVADEVSAMLTTLQERFHHFRNNEALLNDIAREGAQKARERAKATLDAVYQAVGFVSL
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_FRATO
Sequence: MSKVCIVTGKRPATGNNVSHAQNKTKRRFLPNLHAHRFWVESENRYIKLRVSSKGMRIIDKKGIDTVLSDLRAQGHKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: HIS4_TRIEI
Sequence: MNIIPAIDILGGRCVRLYQGDYKQTQIFNDNPVDVAKRWADEGATKLHLVDLDAAKVGQPVNQKTIEAIIKAVDIPIQVGGGLRNYSTVASLLALGVQQAILGTVAIEQPELVSDFCQKFPGQIIVGIDARDGKVATKGWLETSQVLATDLALQMAKLKVAAIIYTDIHRDGTLKGPNIEALRELATAVSIPVIASGGISSINDLLNLLALETIGVKGAIVGRALYTGGISLKEANQAVGQGRWQDVPPNLGSSTFV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEA_ECO27
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PA_I67A2
Sequence: MEDFVRQCFNPMIVELAEKTMKEYGENPKIETNKFAAICTHMEVCFMYSDFHFINERGESIIVEPGDSNALLKHRFEIIEGRDRNMAWTVVNSICNTTGVGKPRFLPDLYDYKEDRFIEIGVTRREIHIYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLDNFRAYVDGFEPNGYIEGKLSQMSREVNARIEPFLKTTPRPLRLPCGPPCFQRSKFLLMDALKLNIEDPSHEGEGIPLYDAVRCMKTFFGWKEPTIVKPHEKGINSNYLLAWKQVLAEIQDIEDEKKIPRIKNMKKTSPLKWALGENMAPEKVDFDDCKDVSDLKQYDSDEPEFRSLASWIQNEFNKACELTDSSWLELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCILEIGDMVLRTAIGQVARPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNCLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYESIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: THIK_YEAST
Sequence: MSQRLQSIKDHLVESAMGKGESKRKNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQIGVVSMCIGTGMGAAAIFIKE
What is the function of this protein?
Responsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs).
What are the official names of this protein?
3-ketoacyl-CoA thiolase, peroxisomal, Acetyl-CoA acyltransferase, Beta-ketothiolase, Peroxisomal 3-oxoacyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Peroxisome. Mitochondrion intermembrane space.
Protein: GUAC_STAA2
Sequence: MKIFDYEDIQLIPNKCIVESRSECDTTIQFGPKKFKLPVVPANMQTVMNEKLAKWFAENDYFYIMHRFDEEARIPFIKHMQNSGLFASISVGVKKAEFDFIEKLAQEKLIPEYITIDIAHGHSDSVINMIKHIKNHIPDSFVIAGNVGTPEGVRELENAGADATKVGIGPGRVCITKIKTGFGTGGWQLAALNICSKAARKPLIADGGIRTHGDIAKSIRFGASMVMIGSLFAAHEESPGETVELDGKQYKEYFGSASEFQKGEHKNVEGKKMFVEHKGSLMDTLKEMQQDLQSSISYAGGKDLKSLRTVDYVIVRNSIFNGDRD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: SOTB_MANSM
Sequence: MLNRKLVNRVEYFRVIVMAFAAFVFNTTEFVPVALLSDIADSFQMPVSNTGLMITIYAWIVSLCSLPCMLMTARLERRRLLISLFILFIASHILSAFAWNYEVLLIARAGVALTHSIFWSITAALTIRIAPKNKKTQALGLLALGSSLAMVLGLPLGRIIGQAFGWRTTFTLIGVFAALILILIVRLLPKIPSQNAGSLKSLPVLARRPMLITLYIFTILVISAHFTAYSYIEPFMIQIGRVSANKATAVLLIFGVSGVVASVLFSRLYRIAPIKFLLSSVAILTLALICLYGVSGISGAIFALVFIWGVAISALSLAMQMKVLQLAPDATDVATAIYSGIYNIGIGGGALIGNQVMQHLGLANIGYVGAVLGAVSIIWFILMFLKFSRVPLNIVNQ
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.