PharMolix/UniProtQA huggingface dataset:
Protein: GATP1_SOLLC
Sequence: MAKISRLFGSTVKAAITAQAGFHGKRIPAVSSLQEHIVKSTPARYNSTQACLENDISGTDNKGFKGHDMLAPFTAGWQSTDVDPLIIEKSEGSHVYDMQGRKYIDTLAGLWCTALGGNEPRLVDAATKQLNTLPFYHSFWNRTTKPSLDLAKELLDMFTAKKMAKAFFTNSGSEANDTQVKLVWYYNNALGRPNKKKFIARAKAYHGSTLISASLTGLPALHQNFDLPAPFVLHTDCPHYWRYHLPGETEEEFSTRLAKNLEDLILKEGPETIAAFIAEPVMGAGGVIPPPATYFDKIQAVVKKYDILFIADEVICAFGRLGTMFGSDMYNIKPDLVTLAKALSSAYMPIGAVLVSPEVSDVIHSQSNKLGSFSHGFTYSGHPVACAVALEAIKIYKERNMVERVNRISPKFQEGLKAFSDSPIIGEIRGLGLILATEFANNKSPNDHFPPEWGVGAYFGAQCQKNGMLVRVAGDTIMMSPPFVVTPEELDELIRIYGKALRETEKRVEELKSQK
What is the function of this protein?
Transaminase that degrades gamma-amino butyric acid (GABA) and uses pyruvate or glyoxylate as amino-group acceptor.  Cannot use beta-alanine, ornithine, acetylornithine, serine, glycine, asparagine, glutamine, glutamate, valine, leucine, isoleucine, methionine, phenylalanine, histidine, lysine, arginine, aspartate, threonine, tyrosine, tryptophan, proline, or cysteine as amino donors.  Acts predominantly in vegetative tissues.
What are the official names of this protein?
Gamma aminobutyrate transaminase 1, mitochondrial, Gamma-aminobutyrate transaminase isozyme 1, LeGABA-TP1, SlGABA-T1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL15_DEHM1
Sequence: MRLNELSPAPGSKKDRKRVGRGDAGRGNYSGRGMKGQKARSGGATRPGFEGGQLPIYLRLPRKRGFFNPFRIEYTVVNIEQLNIFEAGTEVTPETMLAAGLIRNFVKPVKILAAGHIDRALEVSAHKFSQAAKAQIEAAGGKVQEIDYAAEIE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: YIDC_NEIM0
Sequence: MDFKRLTAFFAIALVIMIGWEKMFPTPKPVPAPQQTAQQQAVTASAEAALAPATPITVTTDTVQAVIDEKSGDLRRLTLLKYKATGDENKPFILFGDGKEYTYVAQSELLDAQGNNILKGIGFSAPKKQYSLEGDKVEVRLSAPETRGLKIDKVYTFTKGSYLVNVRFDIANGSGQTANLSADYRIVRDHSEPEGQGYFTHSYVGPVVYTPEGNFQKVSFSDLDDDAKSGKSEAEYIRKTPTGWLGMIEHHFMSTWILQPKGGQSVCAAGDCRIDIKRRNDKLYSTSVSVPLAAIQNGAKSEASINLYAGPQTTSVIANIADNLQLAKDYGKVHWFASPLFWLLNQLHNIIGNWGWAIIVLTIIVKAVLYPLTNASYRSMAKMRAAAPKLQAIKEKYGDDRMAQQQAMMQLYTDEKINPLGGCLPMLLQIPVFIGLYWALFASVELRQAPWLGWITDLSRADPYYILPIIMAATMFAQTYLNPPPTDPMQAKMMKIMPLVFSVMFFFFPAGLVLYWVVNNLLTIAQQWHINRSIEKQRAQGEVVS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SEN54_SCHPO
Sequence: MDAQDEDNPFTNLETTVDVTEEIQDWRFLSNVEKDQGTYTIPKRGQKDFEPDGTNKQHSALDLSRKAMFDALSVERLISAKHAIIATWNAQNGMSCVEKAHGPLFKTMGTADSQNRMWLLPEETLYLVERGSMECWSEEGLPMSLQAVYSASIPLCGSLENYLVYAHLRRCGFSVIRSNLVPVKEDEYRCDSKIMNFKDLLFLGLGKASQILQTFNFRKLAFPFSKRRRQSILLHDTFYTYEEVYHDLQIVRGYVPIACNLITSSDSLFQITFHAYKPSASFKKSALSEPDFRICVVSSQDTLLPTIFEIDALFSSTPLRQNMPQHMFQRLKEGYRNIIIAIVDYGVISYIRLSDVCFEEKVYTDFSKKGSKRKRVSKKFQQLV
What is the function of this protein?
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  May be required to embody the molecular ruler of the complex (By similarity).
What are the official names of this protein?
Probable tRNA-splicing endonuclease subunit sen54, tRNA-intron endonuclease sen54.
What is the protein family that this protein belongs to?
Belongs to the SEN54 family.
Protein: NCAP_CVEN9
Sequence: MSFTPGKQSSSRASSGNRAGNGILKWADQSDQSSNFQTRGRRAQPKQTATSQPAGGNVVPYYSWFSGITQFQKGKEFQFAEGQGVPIAPGIPATEAKGYWYRHNRRSFKTADGNQRQLLPRWYFYYLGTGPHAKAQYGTNIDGVFWVANKQADVNTPADVVDRDPSSDEAIPTRFPPGTVLPQGYYIEGSGRSVPNSRSTSRASSRASSAGSRNRSNSGTRTPTSGVTSDMADQIASLVLAKLGKDATKPQQVTKQTAKEVRQKILNKPRQKRSPNKQCTVQQCFGKRGPNQNFGGAEMLKLGTSDPQFPILAELAPTAGAFFFGSRLELAKVQNLSGNFDEPQKDVYELRYNGAIRFDSTLPGFETIMKVLNENLNAYQQQDDGTNMSPKPQRQRGQQKGGENEDVSVAAPKSRVQQNKSRELTAEDISLVKQMDDPLTEDNSEM
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the betacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: HCF_DROME
Sequence: MEGSDFVDPAFSSGERISASDLNSEHIIQAENHSFANRISMDMDVPDGHQLDSNLTGFRWKRVLNPTGPQPRPRHGHRAINIKELMVVFGGGNEGIVDELHVYNTVTNQWYVPVLKGDVPNGCAAYGFVVEGTRMFVFGGMIEYGKYSNELYELQATKWEWRKMYPESPDSGLSPCPRLGHSFTMVGEKIFLFGGLANESDDPKNNIPKYLNDLYILDTRGVHSHNGKWIVPKTYGDSPPPRESHTGISFATKSNGNLNLLIYGGMSGCRLGDLWLLETDSMTWSKPKTSGEAPLPRSLHSSTMIGNKMYVFGGWVPLVINDSKSTTEREWKCTNTLAVLDLETMTWENVTLDTVEENVPRARAGHCAVGIQSRLYVWSGRDGYRKAWNNQVCCKDLWYLEVSKPLYAVKVALVRASTHALELSWTATTFAAAYVLQIQKIEQPLNTSSKLLSNNIVQQGTPTSAETSGINISANRSGSALGLGVEATSTVLKLEKESLQLSGCQPETNVQPSVNDLLQSMSQPSSPASRADKDPLSSGGGTTFNLSTSVASVHPQISVISSTAAVTGNDTASPSGAINSILQKFRPVVTAVRTSTTTAVSIATSTSDPLSVRVPSTMSANVVLSSSSSTLRIVPSVTASHSLRIASSQASGNNCRSSSAINILKTALPNVAVQSQPTSSTTTSIGGKQYFIQKPLTLAPNVQLQFVKTSGGMTVQTLPKVNFTASKGTPPHGISIANPHLASGITQIQGSTVPGSQIQKPIVSGNVLKLVSPHTMAGGKLIMKNSNILQMGKVTPNVMGGKPAFVITNKQGTPLGNQQIIIVTTGGNVRSVPTSTVMTSAGGSASGTNIVSIVNSTSTTPSPLQALSGQKTLISNQSGVKMLRNISSVQASSSMAFGQKQSGTPIHQKTALYIGGKAVTVMSTNTSMAASGNKVMVLPGTSSNNSPATTTALSARKSFVFNAGGSPRTVTLATKSINAKSIPQSQPVTETNNHSVATIKDTDPMDDIIEQLDGAGDLLKLSESEGQHGSEENENNGENATSSSASALFTGGDTAGPSRAQNPIVMEHPVDIIEDVSGVSSTTDVNETAIVSGDTIESLKMSEKENDDVKSMGEKSILSDDCHQPTTSETEAATILTTIKSAEALVLETAEIRKDHTGCTIGSLKENQDENKKFKQRQESSPSQNIHQFQNVDGSQLEALASAALLQAATSDTTALALKELIERPESETNTRSSNIAEIQQNNVQSTLAVVVPNTSQNENQKWHTVGVFKDLSHTVTSYIDSNCISDSFFDGIDVDNLPDFSKFPRTNLEPGTAYRFRLSAINSCGRGEWGEISSFKTCLPGFPGAPSAIKISKDVKEGAHLTWEPPPAQKTKEIIEYSVYLAVKPTAKDKALSTPQLAFVRVYVGAANQCTVPNASLSNAHVDCSNKPAIIFRIAARNQKGYGPATQVRWLQDPAAAKQHTPTVTPNLKRGPEKSTIGSSNIANTFCSPHKRGRNGLHD
What is the function of this protein?
May be involved in control of the cell cycle.
What are the official names of this protein?
Host cell factor, dHcf.
What are the subcellular locations of this protein?
Nucleus.
Protein: LARE_LACPL
Sequence: MATLATKKATLVAALKDLQRVTVAFSGGIDSTLVLKMALDVLGRDNVTAVVANSELFTDEEFDKAMSLAEELGANVQGTTLDYLSDDHIKNNTPDSWYYAKKMFYSRLNDIAANNGSAAVLDGMIKNDENDYRPGLKARSEAGARSLLQEADFFKTDVRALAQELGLTNWNKVASCSVSSRFPYGTTLTHDNIAQVMAAEKYLRSLGFPTVRVRFHNDIARIELPEARIGDFLVFNDRVNRQLQSLGFRYVTLDLGGFRSGRMNDTLTKAQLATFA
What is the function of this protein?
Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex).  Catalyzes the ATP-dependent incorporation of two sulfur atoms in pyridinium-3,5-biscarboxylic acid mononucleotide (P2CMN) to yield pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN).  The source of sulfur is the enzyme itself: Cys-176 of LarE is the sulfur donor, thereby being converted into dehydroalanine, and is not regenerated in vivo.  Thus, two molecules of LarE undergo sacrificial sulfur transfer to create one P2TMN (PubMed:27114550).  Binds nickel (PubMed:24710389).  Is required for the activation of the lactate racemase LarA (PubMed:24710389).  May also be involved in the activation of other nickel-pincer cofactor-dependent enzymes (PubMed:27114550).
What are the official names of this protein?
Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase, Lactate racemase accessory protein LarE, Lactate racemase activation protein LarE, Lactate racemase maturation protein LarE, Lactate racemization operon protein LarE, Nickel-pincer cofactor biosynthesis protein LarE, Pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase, P2CMN sulfurtransferase.
What is the protein family that this protein belongs to?
Belongs to the LarE family.
Protein: BMP3_BOVIN
Sequence: MAGARGLLHLWLSCLCVSLAQGQRLRQPFPELRVAVPADRAAGGGPESPLQPLDQVSEHMLRLYDRYSGGRTEEARTPGNSERGSPSLRPQPLREGNTVRSFRAGAAGMLENKELHIFNLTSLTKSENILSATLYFYIRELINISLSCPVSQECSHHAQRKHIQIDLSAWILKSSGNQSQLLGHLSVDGGKPHRDFVSWLSKDITQLLRKAKENEEFLIGFNITTKGHQLPKKMTPSPEPYILVYANDAAISEPESVVSSLQGHRNFPTGAVPKLDSQSRSAPSIERRRRKRSTGVLLPLQNNELPGAEYQYKEDEVWEERKPYKTLQTQPPDKSKNKKKQRKGPQQKSQTLQFDEQTLKKARRKQWIEPRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVVPGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCACR
What is the function of this protein?
Induces cartilage and bone formation.
What are the official names of this protein?
Bone morphogenetic protein 3, BMP-3, Osteogenin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURT_ALCBS
Sequence: MTVIGTPFTDNATRVMLLGSGELGREVALELIRYGCEVIAVDRYAHAPAMQVAQHSHVINMLDGTALRAVVEQVKPALIVPEIEAIATDELVKLEAEGYTVVPTARAAQLTMNREGIRCLAAEELSLPTSPYRFADSLAGYQQAVREIGFPCVVKPVMSSSGKGQSTLKNEADILPAWEYAQSGGRAGKGRVIVEGFVDFDYEITLLTVRHKAGSEIKTSYCAPIGHRQENGDYQESWQPQPMSAAALQASREVALAITDALGGLGIFGVELFIKGDQVYFSEVSPRPHDTGLVTLISQTLSEFALHARAILGLPIPTIEQRGASASSVLLIQGQSEAMRYHGLNTALANADTEVRLFGKPDINGSRRLGVALAKADTIDAARDKANTAIAAFKVDL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: OBE3_ARATH
Sequence: MIGEKDLAGDGECSRTKTSKPRFSNLNNQTHQDDKTGQYHQKGVDFLNVRSNNLDGGFSSKSSPRSGNELTLSYLCENSGKLAESLGQKGKEVVTFSENSSYDDKWVERDFFNLREMNPNSSKRKAHEEEEEAEEEEDKKSNKIETLNLSLALPDVSLSLTASNAVKRPRVVTSERTTTSFSNDFTATAPSMSYSYSHPFSHNISCSMTRNSTDFDCSVGKDDHIWCAGEGTNGSVHSRFRPIGDGGVALANNPVSGKPSSSADYSFFPSELPARPGNEVTISGDSRKKVANLEDNDAVRSERVLYDIVSKSISSVALIIQGMADETLESAKEYLRNLIDSPEKKEKLVNLQNQIDKRSDLSKETLSKCVKDQLDILVAVRTGLKYFLSGKIRIPMNELVEIFLFLRCRNVNCKSLLPVDDCECKICSNNKGFCSSCMCPVCLRFDSASNTCSWVGCDVCSHWCHAACGIQKNLIKPGHSLKGQRGTTEMMFHCIGCAHKSEMFGFVKDVFVCCAKNWGLETLIKELDCVRKVFRGSDDAKGKALHLKANEMVKKLESKQISPLDASNFIIQFFNYAESIPEIPDPPRELTVAAETSYRKDEASVTPSTSKDQKKKSFALTDAMMNSFDSLESMVRIKEAETRMFQKKADEARIEAESFKRMIEMKTEKMEEEYTEKLARLCLQETEERRRNKLEELKKLENSHCDYRNMKLRMEAEIAGLLKRMEVTRQQLV
What is the function of this protein?
Probable transcription factor that functions redundantly with OBE4 in specification of the hypophysis and establishment of the embryonic root (PubMed:22378640).  Involved in the activation of ARF5/MP-dependent gene expression during embryonic root meristem initiation (PubMed:22378640).  Involved in shoot meristem homeostasis (PubMed:27196372).
What are the official names of this protein?
Protein OBERON 3, Protein TITANIA 1, Protein WUS ENHANCER 9.
What are the subcellular locations of this protein?
Nucleus.
Protein: HCP_BURCM
Sequence: MFCYQCEQTDRTGARPGCASAKGNCGKDSTTADLQDLLVHAVKGIAQYGAIARTMGVPDREAERFVLYAMFTTLTNVNFHAARFVALLREAAQTRDRVKAACEAHARAAGTAVPVLHGPAEWQPADDLAGLLKQAASVGIDAGLDTVGADIVGLRALVLYGLKGVCAYAHHAQVLGYERDDIYEGVDAALAFLAGNPADVDALLAHALDLGRLNLTVMELLDNANTGRFGVQQPSAVRVSPVAGKAILVSGHDLGDLHALLEQTAGTGIQVYTHGEMLPAHAYPSLKAFPHLAGNYGGAWQDQQSDFARFPGPILMTSNCIIEPLPQYRQRIFTTGPVGWPGVRHLEHHDFPTLIRAAQALPGFQATAPEQTITVGFGRHAVLGVADKVIDAVKAGQIRHFFLIGGCDGAAPGRNYYTEFAEQAPDDTVVMTLGCNKYRFNRHAFGDIGGIPRLLDIGQCNDSYSAIRIATALADAFECGVNDLPLSLVISWFEQKAAAVLLTLLALGIRNIRLGPTLPAFVTPGVLAVLVDQFGIQPIGDAGADLAAALARRAA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_PASMU
Sequence: MQTFNIAVLSGDGIGPEIIAEAIKVLDVVQQKYAFKLNYRTFDVGGIAIDNHGTPLPEATLKGCEESDAILFGSVGGPKWEHLPPAQQPERGALLPLRKHFALFCNLRPATLYKGLEKFCPLRADISAKGFDMVTVRELTGGIYFGQPKGREGEGANEKAFDTEVYHRYEIERIARVAFETAMKRSKHVTSVDKANVLISSVLWREVVCDVAKDYPEVTLDHIYIDNATMQLIKQPEFFDVLLCSNIFGDIISDECAMITGSMGMLPSASLNEKGFGLYEPAGGSAPDIAGKGIANPIAQILSAAMMLRHSFNLNDAATAIENAVKNVLAEGHRTADLADESQPLSTKQMGDLIAQAVE
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBK1_CAEEL
Sequence: MNTADVPDNLQSWGQQPSSSYSNTQQHSQMTNLPPINHNNLCDTEPMNEDFQLQDVQADELQKQQKQQEQQHIQQQNAQRFIAQSRQPHSNILRFPQPPITSIKTNSHAFYPQQEVTQVRPKKHRVSMTNAEAALTPGMPPEKQAAKKRNIGQFSTDTVPAGIGMIGIPFESTSKPLQIQQFRNPQDAPVRKLTSDLIKTYKAINESFYLRKQVRRDRHKSQDAGKPKGSKDGSGASLTDTFSIHNAIPITSSDNHYQQDAHQNAPPLLDTNAPPTSTMVVPMRTETDLQQQQRQKSSRGGPYNNGYDDQNYDYILKNGEIFDKRYVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHTGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDYSKFKDLIKRMLQFDPKQRISPYYVVRHPFLKQKEERVPSQPPVSHSNLQQQQQLYIQQPSSQMSQVMESPSVGSVYVEDNGMYRQAPGSSANPISVTSSFDEGDAMEVDAGRRRFSAHQQNYHNPNYQYSQPQQQQQQQYQQTQRTQLEQQQKQAQLQQQLQQQQMQQQQQQQQQRQHMPQAQSSSQQHLQSRARPRQQDQNEWRNQFELDDTFQQKQRKVDDSVSNQISRNQFNPQQVSMTHGNVNANNREMEKLDYPNNKL
What is the function of this protein?
Possible role in the function of olfactory neurons.
What are the official names of this protein?
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1, Dual specificity Yak1-related kinase mbk-1, Minibrain Kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
Protein: PLHD1_CAEEL
Sequence: MTTKTTPKELKAKKESKKKGSAPEPPKNGPPRTSPPNTIEKKGILRSLSFQFSNLTRKKGNDYDLTPEEEGDGYGDEMGPVLGVQNYGILMKKYKRKNRSARWAKRFFVLKECFLIYYSTSYKKVFEKTRRIDLHPKGIIPLIGCSIVSGGDVDKKNCLLIAHPQLPSAIIVAASDHQTQEMWLKALRSATKISYKNTVVGETMIRELENRGVLLNEEKKSYEERLEAEAKARKEEHDRADELAKDKEELEAEREKLIRTTKKLKDDLQNVKNELKMTNEMKKTLEQEKMSLNSKTEHLQANMESLNIEKEKIHEQLQEIVREREKVLIDNQNLSTDKCQLNNRLMEIETSRNCIMTEKEKIENLLKMNEQKTQDLEKERQYYTMKTSELMDHLKEVSEQRDLTESELKEQMMARLGAEKQLQAAEKALEHLEMALKMTGAQMTELQEHIMPDVHKLREFFEQCAEESRFEANRTGIMRNAVYARKSIFDVAFSELDGHSLDVFEKFCEYNSQVLPVREKPQKLHKTWKQSSFKRIGSIRRSKRGIRSSFRKKTDSITTQPREKEPLMQL
What are the official names of this protein?
Pleckstrin homology domain-containing family D member 1, PH domain-containing family D member 1.
What is the protein family that this protein belongs to?
Belongs to the PLEKHD1 family.
Protein: RISB_CLONN
Sequence: MRVYEGNLISEGKKYGIVVGRFNEFIGSKLLSGALDALKRHGVKEDEIEISWVPGAFEIPLVAKKMAKTKKYDSVICLGAVIKGSTAHFDYVSSEVSKGIANVSLDTEVPVIFGVLTTDNIEQAIERAGTKAGNKGYEAAVTAIEMANLLSEI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: TEA1_SCHPO
Sequence: MSFLFKRNKGSAHKPTKPNFSKTSTTPSTSQLKHSHESNVKMSTSTVTEHRKKPTGSGSHITASPWSKLTVRGSSNVLPRYSHASHLYAEGGQEIYIFGGVASDSQPKNDLWVLNLATSQFTSLRSLGETPSPRLGHASILIGNAFIVFGGLTNHDVADRQDNSLYLLNTSSLVWQKANASGARPSGRYGHTISCLGSKICLFGGRLLDYYFNDLVCFDLNNLNTSDSRWELASVVNDPPPARAGHVAFTFSDKLYIFGGTDGANFFNDLWCYHPKQSAWSKVETFGVAPNPRAGHAASVVEGILYVFGGRASDGTFLNDLYAFRLSSKHWYKLSDLPFTPSPRSSHTLSCSGLTLVLIGGKQGKGASDSNVYMLDTSRFRLGSVPTTSGRQRNTSFFSNSTGNTNPSAFNGLLTSSRIPSYNGSKVRSTSHPSRQQYIGSSNSRFNTRHQTISTPVSGRASNDLPSPVVPTRSNSSSILQPSYNLNSHSSDRRNTNDDDQSSLNSQQLSNQAKAQGEVSPTLSFVPSSHSMEQGNGSVASANNAQSEAATRSINSISEVSEVRFPEQSSVKTVDERKSLDGRITSVTLETLVEKYSELSKQQIVEWFKSKLYEILRDSASKIDSLTEKLKVANAEKNAALCEAALEKVPLAKHNKLSDGTFSTPDKENVQSTNDAHIMQENFSLHKALEVMRETSSDLDKQLKDATASQKELIVQTSSFQKELVEERERHNAISKRLQEIESLYRDRELLVTNLEDQLVDQTVTINKFAFERDQFRERSMGFENTIKDLTRKMEATDMLNVSLHESLRSVQTENSELVTEMALLKAELVKKQAIIDANANIYDKLTADHTNYETVSADINQNLKETLDKLLNGSSDFKNNEIELLHDQIRITNAKLEKREKLINASKYIEDTLRSEIQEAAEKVSNLEFSNFNLKEENSNMQLQLMKALEQRNTGAKQLVNLRMQLSTATSELDMLKLKLRTTALALEESPDDYSDILSILRADMSPFHDLHKQCGVLIDTLNGVKRGFGIFEKKFTDYHKFLENISDKLKSEEDTSLETPIHENQSIQSDQIKEVGEVLSAIKSLSDSVMLLKNQIDDLAKEKLPLSSSDDEKVNIKEKTDFMKLLVKSGLSNPPAKEPVHDNEN
What is the function of this protein?
Cell polarity protein.  Acts as an end marker, directing the growth machinery to the cell poles.  Involved in the regulation of microtubular organization, affecting the maintenance of a single central axis.  Prevents the curling of microtubule tips around the cell ends and is required for the retention of polarity factors such as pom1, tip1 and tea2 at the cell ends, necessary for the cell to grow in a straight line.  Links tip1 and tea4 in a common complex.
What are the official names of this protein?
Tip elongation aberrant protein 1, Altered polarity protein 8, Cell polarity protein tea1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Present at both poles of the cell throughout the cell cycle whether they are growing or not. Located at the ends of microtubules growing towards the cell poles. An intact microtubular skeleton is required to maintain the location at the cell tips; on the other hand, a normally organized actin cytoskeleton is not required.
Protein: RS7_METRJ
Sequence: MSRRHSAEKREIIPDPKYGDVVLTKFMNSIMYEGKKSTAERIVYGAFDIVENRARANPIEVFRAALDNVAPMIEVRSRRVGGATYQVPVEVRTERRQALAIRWLIQAARSRNDRTMVERLSAELLDAANNRGNAVKKREDTHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS10_RUTMC
Sequence: MSNQNIRIKLKAFDHRLIDKSALEIVETAKRTGASVRGPIPLPTKKERFTVLTSPHVNKKARDQYELRTYVRLMDVISPTDKTVDALMKLDLAAGVDVAIKLN
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RUVB_TRIV2
Sequence: MAIISSKKQPPEPNGQPNKRPESAPAAPKEKVLQPEAAIDEQGKQEESIRPQKFADYIGQKDLKDVLDIAIKAAKSRGEVLDHLLLYGPPGLGKTTMAMILASEMGVNYKITSAPALERPRDIVGLLVNLKPGDILFIDEIHRLSRMTEEILYPAMEDYRLDITVGKGSSARIRSIPLSKFTLVGATTRVGALTSPLRDRFGLIQKLRFYEVDELSQIVLRSAQLLQTQVTDDGATEIARRSRGTPRIANRLLKRVRDYAQVKSCTEVSQNIAAEALQLFQVDPCGLDWTDRRMLSVIIEQFNGGPVGLETIAAATGEDTQTIEEVYEPYLMQIGYLSRTPRGRTATKAAYKHMGFTPPNEQLSLL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YORS_SCHPO
Sequence: MDFKSRKYKIKKHPKDCKLHAKKYRGTLNSKGKNDNDCLIMCMRCRKVKGIDSYSKTQWSKTFTFVRGRTVSVSDPKVICRTCQPKQHDSIWCTACQQTKGINEFSKAQRHVLDPRCQICVHSQRNDGDDNLESDKFVDPFIGDDSDLDDDIYIHDKQTINSEYADDVSDNTDEERTESKGQQESNSAEEYDDDDSDEDRMEEIFQQFKKEKQIV
What is the function of this protein?
Required for meiotic chromosome segregation.
What are the official names of this protein?
Meiotic chromosome segregation protein P8B7.28c.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RPAP3_HUMAN
Sequence: MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELKKRYGG
What is the function of this protein?
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation.
What are the official names of this protein?
RNA polymerase II-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the RPAP3 family.