PharMolix/UniProtQA huggingface dataset:
Protein: GHR_MACMU
Sequence: MDLWQLLLTLALAGSSDAFSGSEPTAAILSRASWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDAVHHGSKSLGPIQLFYTRRNIQGQTQEWKECPDYVSAGENSCYFNSSFTSVWIPYCIKLTSNGDTVDGKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADILVRWEAPPNADIQKGWMVLEYELQYKEVNETKWKMMDPILSTSVPVYSLKVDKEYEVLVRSKRRNSRNYGEFSEVLYVTLPQMNQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGINPDLLKEGKLEEVNAILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKNEGSDTDRLLSSDHQKSHSNLGVKDGDSGRTSCYEPDILETDFNANNIHEGTSEVAQPQRLKGEADLLCLDQKNQNKSPYHDACPATQQPSVIQAEKNKPQPLPTDGAESTHQAAHIQLSNPSSLANIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHLEMVSLCQEDFIMDNAYFCEADAKKCIPVAPHIKVESHIEPSFNQEDIYITTESLTTTAGRPGTTEHIPGSEMPVPDYTSIHIVQSPQGLILNATALPLPGKEFLSSCGYVSTDQLNKIMP
What is the function of this protein?
The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
What are the official names of this protein?
Growth hormone receptor, GH receptor, Somatotropin receptor.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway. SUBCELLULAR LOCATION: [Growth hormone-binding protein]: Secreted. Note=Complexed to a substantial fraction of circulating GH.
Protein: TOP1_BUCAP
Sequence: MCKSLVIVESPVKAKTISKYLGKQYIVKSSVGHVRDLINNKSKNKKNIKKSNIKHNEKTALIQQMGINPYKNWKAEYHILPGKEKIISELKNIANKVHYIYLATDLDREGEAIAWHLKEVIGGNSLKFRRVVFNEITKKSIEKAFQNIGKINMNRVYSQQARRFMDRIVGYMISPLLWKKISRGLSAGRVQSAAVRLITDREYEIKNFIEREHWKISLSLLSKENKKVTMDITHYRNKTFLLNNKKEVNSTIEKIKNLSFIITDRKDKIFKKKPPAPLITSTLQQASNIDLGFSVKKTMFLAQKLYEQGYITYIRTDSYFLSNYAIEKVRSYIENFYGSDFLPKKSNIYSNQKYSQEAHEAIRPSDVQVVNIDNCDPDAKKLYKLIWNYFIASQMKSERYKSIKTTVMADVFKLQSNTKIVLFSGWTKILKKSNNVNFKFPVLDIGTTLILDKILPHQIFTKPPPRFSESSLVRELEKKGIGRPSTYATIITKIKEKGYLKIKKNKFYAAKIGEILITRLKKNFSDLVDYDFTARMEKNLDQVSDKLINWKHLLNSFFDNFSQQLEQAKKPPEEGGMELNTTVPTEIDCSLCNKKMGIKTAVTGVFLSCLGYNSEPNEKRCKNTINLISLNDLSTTKKEEKNFHLKNRCKKCNLVMDVYLINENLKIFICINNPSCNGYNLKKGIFKKSLNCSLKKIKCEKCKNDMLFKTGRFGNFFMCINDTCKNTRKILPNGEISEPKFEPIPFPDILCEKSNTWFVLREGISGIFFAANTFPKSRETRSPFVEELARFEYLLPKKLHYLASAPQRDNKGNKTIVCFNKLNKQQYIASKKEGKFTGWAAFFIDRKWCIVNK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: BETT1_ACIAD
Sequence: MWSKRDEQKTYPPIRLNPFVFWSSAISISIFGMLFVLFPETSQHGLTWIQQQVNQLFGWYYMLVIILSLGFVAWLAFSQVGNIPLGKAQDKPEFGYLVWTSMLFSAGIGIALLYYGVAEPVDHFLRPPEGQGGTVEAAQNAMMYSFLHWGIHGWVLYALVGVTLGYFAFRRDLPLALRSALYPIFGERIHGLVGHMVDGFGILATIISLVTNLGIGALVMISGISYLFPDLPNTSSTLVVTVIMMMLVATLTTVIGIEKGLAWLSRINLRLLYLLLLFVFLTGPTNHLLNGLVQNTGDYLSHFVQKSFDLYLYDKNATGWLASWTIFYWAWWIAWAPFVGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGNTAIDLILNHGQQIIGSLVIQDPALSLFKLLEYLPFHPYVAGIVVVICFVLFLTPVGSGTLMIANLSSQGGSSDSDSPIWLRVFWSIAITIVSIGLLLAGSFSAMQSAVVLCGLPFSVILLLYMFGLAKALKQETQQPVVESHTTETSGSD
What is the function of this protein?
Sodium-independent high-affinity choline uptake system.  Uptake is not proton coupled.  May play a role in metabolic adaptation to choline-containing environments.
What are the official names of this protein?
Osmo-independent choline transporter BetT1.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NTPP_SYNE7
Sequence: MTTPRLILASASPARRRLLATVGLTVEVQPSHFDESLVQLNDPPALVQELAFRKAASVARSQTEPALVLGCDSVLAINGEICGKPASPAEAIARWQQMRGQWGELHTGHALIDSASQRRWLACGTTRVRFAEVEDAEIKAYVATGEPLACAGAFALEGKGGLFIAEIQGCHTNVIGLSLPLLRELLLAADYPLLQAWQT
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRYGT_DROER
Sequence: MLKFVILLSAVACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYTDRVIVTAAHCLQSVSTSSLQIRAGSSYWNSGGVTVKVSSFKNHEGYSARTMVNDIAVIRLSSSLSFSSTIKSISLASSNPPNGAAASVSGWGTQSSGSNSIPSQLQYVNVNIVSQSRCASSTYGYGSDIRDTMICAAASGKDACQGDSGGPLVSGGVLVGVVSWGQGCAYSNYPGVYASVADLRAWVVRNA
What are the official names of this protein?
Trypsin gamma.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: PHEA_MYCMM
Sequence: MARIAYLGPEGTFTQAALLEIAAAGLVPGHDDGGAQPLPVESTPAALDAVRTGAAEFACVPIENSIDGSLAPTLDSLAIGSPLQVFAETTLDVAFSIVVRPGVGAADVRTLAAFPVAAAQVRQWLTAHLPSVELHPAYSNADAARQVAEGQVDAAVTSPLAAAHWALQSLADGVVDESNARTRFLLIGVPGPPPPRTGTDRTSVVLRIANVPGALLDALTEFGMRGIDLTRIESRPTRTGLGTYMFFVDCVGHIADDAVAEALKALHRRCADVRYLGSWPTGQTYAGQPPPADEAAIWLQQLREGKPEASPGPPL
What are the official names of this protein?
Prephenate dehydratase, PDT.
Protein: ISPE_ANADE
Sequence: MRLVTLAPAKVNLVLRVGPVRADGYHDLRTLMVPLDLGDRVDVRVSARRGPVRCTVPGRPELHGPENLAARAAEAFRRRFGVDRAVSIRIEKRTPVTAGLGGGSSDAAAVLRCLARAFRVRDRAALAALALEIGSDVPFFLGPGPAWAAGRGERLSPADVPPLDLVLVYPADPSLAIRAGDAYRWLDEARAGGPQAPRRLGRPGRWRPSLLGNDLQAPCVARKPALQALLGLLVGAGATAAIMSGSGPTVFGVFPGRGAARGAALAIQGRAKGGAAGVQVLLARTVRRHPRVSPWRSPRSASSPSTRRSSRPT
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PMM_ORYSJ
Sequence: MAARKNAGVLALFDVDGTLTAPRKVVTPEMLQFMKQLREHVTVGVVGGSDLVKISEQLGKSVTTDYDYCFSENGLVAHKNGELIGTQSLKSFLGDDQLKEFINFTLHYIADLDIPIKRGTFIEFRSGMLNVSPIGRNCSQEERDEFEKYDKVHNIRPKMVSVLREKFAHLNLTFSIGGQISFDVFPQGWDKTYCLRYLEEFQEIHFFGDKTYKGGNDYEIFESDRTIGHTVTSPDDTAEQCRSLFMSK
What is the function of this protein?
Catalyzes the interconversion of mannose-6-phosphate to mannose-1-phosphate, the precursor for the synthesis of GDP-mannose (Probable) (PubMed:20920368).  GDP-mannose is an essential sugar nucleotide for the synthesis of D-mannose-containing cell wall polysaccharides (galactomannans and glucomannans), glycolipids, glycoproteins and the antioxidant L-ascorbate (Probable).  Can complement the yeast temperature-sensitive mutant sec53-6 (PubMed:17217471).
What are the official names of this protein?
Phosphomannomutase, OsPMM.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic PMM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_STRPN
Sequence: MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTEMGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLAELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDKPETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCO_RAT
Sequence: MKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTSYYSQDDNCAVGSEDIQFQKKNEREEPSNAKVSEKSNSYLTISPEENKLKDDYTVDECKIWKQSKLSLPVVEALPTVDSHEESSSVVVGSENIENSSSSSTSETSPISKLDEIENSGTLSVAKPGDTEQPEADCDAGEAADADASVEQPAFVSAPESLVGQHIENVSSSHGKEKVTKSEFESKVSVSEQDGGDPKSALNASDTLKNESSDYTKPRETDPTSVTSPKDPEDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERTVQSFPLDEQMYAKYVKMFIKYIKVELLSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGDKSISENATATTEPKMPESTGVSTPVPSPEYIIKEVHTHDTEPPTSDPPKESPIVQLVQEEEEEASPSTVTLLGSGEQEDESSSWFESETQILCSELTSICCISSFSEYLYKWCSVRIALYRQHSRTVSKGKDVSPQPSLLPPVDSVEVSVLQPPSGNVDKEDMERELETVALDDLSSVHQAHVRNHTVDTVELEPSYPQTLSQSLPLDVTPEMDSLSTVEGSESVKSEGGHKPSQVMPQESSVEFDDETEKKPESFSSVAKLSVIYETSKVNEVMDGPVKEDIVSTHVVTKFPETKFPETVAPPPINTAAVPESEGMETKPSLADTLKHVVTPVTDPSLPEVKEDEQSPDDALLRGLQRTATDFYAELQNSTDLGYGNGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQIVSNLSATVAELKREVSDRQSYLVMSLVLCVVLGLMLCMQRCRNTSQFDGDYTSKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEDPNDLYIVEPLKFSPEKKKKRCKYKTEKIETIKPADPLHPIANGDIKGRKPFTNQRDFSSMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQTQKTKLRRGLKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI
What is the function of this protein?
Required for bone modeling during late embryogenesis.  Regulates type I collagen synthesis in osteoblasts during their postnatal maturation (By similarity).
What are the official names of this protein?
SUN domain-containing ossification factor, Membrane protein CH1, Protein osteopotentia homolog, SUN-like protein 1.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: UVRB_PSEF5
Sequence: MSEFQLVTRFQPAGDQPEAIRLMVEGIEAGLAHQTLLGVTGSGKTFSIANVIAQVQRPTLVLAPNKTLAAQLYGEFKAFFPNNAVEYFVSYYDYYQPEAYVPSSDTFIEKDASINDHIEQMRLSATKALLERKDAIIVTTVSCIYGLGSPETYLKMVLHVDRGDKLDQRALLRRLADLQYTRNDMDFARATFRVRGDVIDIYPAESDLEAIRIELFDDEVESISAFDPLTGEVIRKLPRFTFYPKSHYVTPRETLLDAIEGIKVELQERLEYLRSNNKLVEAQRLEQRTRFDLEMILELGYCNGIENYSRYLSGRPAGAAPPTLYDYLPADALLVIDESHVSVPQVGAMYKGDRSRKETLVEYGFRLPSALDNRPMRFDEWEGVSPQTIFVSATPGNYEAEHAGRVVEQVVRPTGLVDPQVEVRPALTQVDDLLSEITKRVAVEERVLVTTLTKRMAEDLTDYLADHGVRVRYLHSDIDTVERVEIIRDLRLGTFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGRAILYADRITGSMERAIGETERRRDKQIAFNLANGITPKGVVKDVADIMEGATVPGSRSKKRKGMAKAAEENARYENELRSPSEITKRIRQLEEKMYQLARDLEFEAAAQMRDEITKLRERLLTV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_BRUA1
Sequence: MARDATKLEATVAKLKKHWAESAPRDMRAAFSTDPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHDEPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAAVSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRKA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSH_PLABA
Sequence: MRNQLVNASLKKTIYASNMINKDQNQNTNQQNMRHPNMNNPNVNNPNMNYPNVNNPNMNNQNMNNSNMNNPNVNNPNVNNPNVNNPNVNNPNVNNPNVNNPNVNNPNVNNPNMNNPNVNNPNVNNPNMNNPNMNNPNMNNPNVNYPNMNIPNMNYPNMNNPNVNYPNMNNPNMNYPNMNFQQYPYIIPPPQQQMAMFFNDWRTVLAPLKGCRIKQQFDDREFLADYVMGMKFDFNNKYLILDAGNELLKFTAIENSEFFSRNCLPKMCIPINMKILSYGKELVKPDIMVEKDCSFTICCLNRPIIKMYDFSNNNNKKLIGTIRPPFSCCSFKFDLFDASNKKIIYMDDTCCQMSILCPCPFGPFKFSNYYLRDAKTHERIAHLRKEVPFLKFVKRDIDNYTLNFEDVQNPEWKMMLLAFSLFLDYIYYDAK
What is the function of this protein?
Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane resulting in collapse of the phospholipid asymmetry (By similarity).  Preferentially, mediates calcium-dependent phosphatidylethanolamine externalization (By similarity).  During the liver stage, plays a role in the interaction with, and thus invasion of, host hepatocytes, possibly by interacting with host carbamoyl-phosphate synthase CPS1 (PubMed:34799567).  Dispensable for host erythrocyte invasion and asexual parasite development (By similarity).
What are the official names of this protein?
Phospholipid scramblase, PbPLS.
What is the protein family that this protein belongs to?
Belongs to the phospholipid scramblase family.
Protein: FPGS2_ARATH
Sequence: MLVCGKGFLKCRAPGVPFFCDKRKSFFTKTKRGFHSLPLGTGVRVYFNNNLRYSSNSIEVVEKAAINMGSKEDKADNPALSSYDDAMEALSTLISRRNRGDRTPTKGNRDKLEQVVTYLKILDLEDKIKELKVIHVAGTKGKGSTCVFSEAILRNCGFRTGMFTSPHLIDVRERFRIDGLDISEEKFLQYFWECWKLLKEKAVDGLTMPPLFQFLTVLAFKIFVCEKVDVAVIEVGLGGKLDSTNVIQKPVVCGIASLGMDHMDILGNTLADIAFHKAGIFKPQIPAFTVPQLSEAMDVLQKTANNLEVPLEVVAPLEPKKLDGVTLGLSGDHQLVNAGLAVSLSRCWLQRTGNWKKIFPNESKETEIPVAFCRGLATARLHGRAQVVHDVVSDPQDSSDSMETPCGDLIFYLDGAHSPESMEACGRWFSSAVRGDKSLSTAVNGYMRHGEYGTDLNRVSKQILLFNCMEVRDPQVLLPKLVTTCASSGTHFSRALFVPSMSTYNKVISGASAIPSDTRRKDLTWQFRLQRLWEKSIQGTDAGLDHTLKPDGITALPPHDFLCGDAPQCGGPAGTPVTSSAVMPSLPLTINWLRDCVRRNPSLKLEVLVTGSLHLVGDVLRLLKR
What is the function of this protein?
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.  Essential for organellar and whole-plant folate homeostasis.
What are the official names of this protein?
Folylpolyglutamate synthase, DHFS-FPGS homolog C, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolylpolyglutamate synthase, Tetrahydrofolate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Mitochondrion matrix.
Protein: GATC_RHORT
Sequence: MALDKTTVAKIATLARLDIEEDRMEALAGELSGILDWIEQLAEVDTSGVAAMTSVADLALAWREDAVTDGGYADRVLANAPESQDGCFLVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: COXX_RICBR
Sequence: MNSLTKSINLDKVSYPQSTVKDYILLMKPRVMSLVVFTGFSGMWLAPNSLHPFISVIALICIAIGAGSAGAINMWYDRDIDALMKRTQKRPIVRGAIEADEALSFGLIMAFFSVFFMALCVNFLSALLLLFTIFYYICIYTMWLKRSSIQNIVIGGAAGALPPVIGYASVSGSVSLDSVILFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPVIKGALYTKKQILIYSVLLFLTSLKPFFVGMSNIIYLVIAAVLGLVFLYYSISLFYDNADNKQAKRFFAYSIFYLFFIFLLLDFCRV
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METN2_PSEF5
Sequence: MSVATLQRKLPEAAPRRAGQTELHPELNRAQVRFIGLGKTYQGQQGPVQALHDIDLSIQRGEVFGIIGRSGAGKSSLIRTINRLEQPSSGRVLIDQVDIGDFDEDRLVALRRRIGMIFQHFNLMSAKTVWHNVELPLKVAGVPKAERERKVRELLELVGLKDKHRAYPAQLSGGQKQRVGIARALVHDPEILLCDEATSALDPETTQSILGLLKEINQRLGLTIILITHEMAVIRDICDRVVVLEHGRIVEQGPVWEVFGNPQHEVSKTLLAPLQHGLPEELQNRLQSHPTSSDAALVLSLRFTGSSHEEPDLAALFGALGGRVRLLQGGVERIQGHALGQLLLAVQGSSLEAAQLRQRAGQWAQQVEVLGYVV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VE8E2_HPV05
Sequence: MKLKMLLLSSTPPGSPGGQADTNTTPATPTTSTTAVDSTSRQLTTSKQPQQTETRGRRYGRRPSSKSRRSQTQQRRSRSRHRSRSRSRSRSKSQTHTTRSTTRSRSTSLTKTRALTSRSRSRGRSPTTCRRGGGRSPRRRSRSPSTSSSCTTQRSQRARAESSTTRGARGSRGSRGGSRGGRGRRRGRSSSSSSPAHKRSRGGSAKLRGVSPGEVGGSLRSVSSKHTGRLGRLLEEARDPPVIIVKGAANTLKCFRNRAKIKYMGLFRSFSTTWSWVAGDGTERLGRPRMLISFSSYTQRRDFDEAVRYPKGVDKAYGNLDSL
What is the function of this protein?
Plays a role in limiting the replication of viral DNA in keratinocytes.  Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.
What are the official names of this protein?
Protein E8^E2C.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E8^E2C protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CQ091_HUMAN
Sequence: MGWEGPNSRVDDTFWASWRAFAQIGPARSGFRLETLAGLRSRRLKQPKAFCLRDVAP
What are the official names of this protein?
Putative uncharacterized protein encoded by MIR22HG.
Protein: UREE_BURM9
Sequence: MRTIDKRIAPNVRLAATLVARAPALTLAYDARCKSRLAATLDTGEDVALVLPRGTVLRDGDVLVADDGALVRVAAAHEAVLLVRAPDALTLTRAAYHLGNRHTPVEVGAGCLKLEYDPALADMLTRLGATVERASAPFQPEAGAYGGGHRHGHDATFAEDYALAQQVFDEHHGHSHSHSHSHSHDHDHDHDHDHDHDHQHGPSCSHGHHHGHR
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VTF3S_VACCW
Sequence: MFEPVPDLNLEASVELGEVNIDQTTPMIKENSGFISRSRRLFAHRSKDDERKLALRFFLQRLYFLDHREIHYLFRCVDAVKDVTITKKNNIIVAPYIALLTIASKGCKLTETMIEAFFPELYNEHSKKFKFNSQVSIIQEKLGYQFGNYHVYDFEPYYSTVALAIRDEHSSGIFNIRQESYLVSSLSEITYRFYLINLKSDLVQWSASTGAVINQMVNTVLITVYEKLQLVIENDSQFTCSLAVESKLPIKLLKDRNELFTKFINELKKTSSFKISKRDKDTLLKYFT
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from intermediate gene promoters.
What are the official names of this protein?
Intermediate transcription factor 3 small subunit, VITF-3 32 kDa subunit, VITF-3 small subunit.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG134 family.
Protein: GATA_DEHMB
Sequence: MTDLVKLTIAQSHKLLKDHKISSAELTKAHLERIEKLEPEIKAFMTVCPETALSQAEAADKAIKQGDIRPLTGIPMALKDVLCTKGIRTTCSSKMLENFVPPYNAHVVDKLAKEGAVLLGKTNMDEFAMGSSTENSAYFTTRNPWNTDKVPGGSSGGSAACVAASEAVFSLGSDTGGSIRQPASFCSVTGYKPSYGMVSRYGLVAFASSLDQIGPFTKDAMDCALVMNAIAGFDDRDSTSVPQTVPDFSSGLDGNIKGFKLGVPKEYFSQNMRPDITEKINDALGVLSGLGASIDREVSLPHTPYALAVYYILAPSEASANLSRYDGVKYGYSYNPTENMWEAMEKTRAKGFGPEVKRRIMIGTYALSAGYYDAWYVKAQKVRTLISQEFNNAFEKYDALITPTTPNLPFSIGEKLNDPFEMYMCDTCTIPINIAGLPAVSIPAGFVDGLPVGLQIIGKPFADQTTMRIAHAFQCATAWHKETPRL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: HSCB_RICB8
Sequence: MQNYFELLGLEQIYNIDLKILEKQYFAMQIKYHPDKAKNLQEKEQNLIIASNLNKAYSTLKDSLKRAEYMLLLYGVNLNDEKVRSKLSALELSIFWDEMELIENTSSYKSLEEIKSKYELMEKAEVNFLAESFKKQDLSDATIKTSKLKYIHTLLSKLQEKMKLCK
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: Y1012_AQUAE
Sequence: MKETIISSMEKFIQKFFEELYLILFDYALKIAQNPIDELLIFGSIAIAYTVIYISGLFFARKINLPYIRKILEIGISVIFYFLVSLLEGKFPQVESLLLLKTLFLVQTIRVFILSLEAFQAFGFTTKLLINIFSILGGISFFIIKLSPFTRRKI
What are the official names of this protein?
Uncharacterized protein aq_1012.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y516_ARCFU
Sequence: MGISSPALWTEFFERYYREEINKLAYKLKSGGDGRSLYVNFVRDLSIFQEGKLGEELIEKPDEVLVHAERGLANATNIYGVSLEGCKPDSTHSQQQGRF
What are the official names of this protein?
Uncharacterized protein AF_0516.
Protein: NTPP_RICPR
Sequence: MKQHIKNLPIILASGSLARVELLDRIKIIPTQIIPAYIDETPNLRELPAPLAIRLAYEKAIKVASQIETSSIIIAADTVTAVGRRILPKATTYEEVKHCIKMVSGRRHRVYTGLCIIKKENNQLTFRQKIVQTIIKFKKLSDEEINFYSSLDEGIDKAGGCKISGYAEAFVSFISGSYSNIMGLPLFETVNALTSLGFRYSNNTPNVYKDPSTNHLSKPSIS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.