PharMolix/UniProtQA huggingface dataset:
Protein: BBP_YARLI
Sequence: MSSTYSSIQRHRKDTSSSGSNTTPLARRRRFDEGPADPGSAPHLDSFVVPPTRHDDGTKRQPGRRKQRWSHGENKVADLLQMPTALTGHLTPEQAEAYAIYYRIEEISQQLRLGDIVPPEDERSPSPPPQYDSMGKRTNTRDARYTRQLEEERHRLIERAQRLIPNYRPPVDYHKPAKTQEVVYIPVNEYPDINFIGQLLGARGKTLKKMEQESGAKICIRGRGSVKQGKGRTDIPFQSTAEDDLHCLIISEDEEKIARAVQLVQQVIDTAASVPEGQNELKRSQLRELAALNGTLRDDENYGGAPQSSSGDEMDDRNKRRNNFMSSIVCHICGSKGHFARDCLEKGTNAGTSENADREYDALMRELQGEGVIDTASQQQSIAQNPNTNNVSKLPPAVTGSNAAPINMRKPMSERGGSFDRFDRGGFNQSNQREPQQQSHQQNMHNTNGNNYDRYDRNFNNSSNSSPELPPWHRPTPPSQPAAPPWLRRDNYKKHDKVSVQQSMQQSPWNRDTRQHQHQHQPPVHHQSMFNNNQSPIGPPGMSSSGFGGYGGAPAGVPGMSVPPGPPGLSKVPPPPPPPGVPGMDGDQPIRHPPPPPPGVIGPPK
What is the function of this protein?
Necessary for the splicing of pre-mRNA.  Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity).
What are the official names of this protein?
Branchpoint-bridging protein.
What is the protein family that this protein belongs to?
Belongs to the BBP/SF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRH_CAMHC
Sequence: MDKKKRILVKFSGEALAGDSGFGIDSTILKFIANEIKSLVDMGVEVGIVIGGGNIIRGVSAAAGGIIKRTSGDHMGMLATVINAIAMREALEFYDVDVRVQSAIKMEAICETFIIGRAKRHLEKGRVVIFAAGTGNPFFTTDTAATLRAIEIESDMIIKATKVNGVYDKDPNKFEEAVLLNSLTYDEALKDNIKVMDDTAIALAKDNHLPIVVCNMFKSGNLCKIADDDLSFCSIVK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPHB5_HUMAN
Sequence: MKLAFLFLGPMALLLLAGYGCVLGASSGNLRTFVGCAVREFTFLAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAHHRVCTYNETKQVTVKLPNCAPGVDPFYTYPVAIRCDCGACSTATTECETI
What is the function of this protein?
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production.  Plays a central role in controlling thyroid cell metabolism.
What are the official names of this protein?
Glycoprotein hormone beta-5, Thyrostimulin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYE1_COXBN
Sequence: MMKSRFCPSPTGLMHLGNARTALFNYLFAKSKDGIFLLRIEDTDVERSKETFDLGLKEDLRWLNLEWQEGPGADEGNGPYHQSKRQAIYDDYYQRLEEADQAYPCFCSEEQLRLSRKIQRSAGKPPRYAGTCRSLSAAEIEKKKAEGLQPALRFRVPDDEVVVFADLVRGEQRFQTNDIGDFIIRRANGTSPFMFCNAIDDALMGVSHVLRGEDHLTNTPRQLLILQALELPVPTYAHIALIVGPDGSPLSKRHGSRGIKELRDNGYLPLALTNYLARLGHYYASDELLSLAELAKGFNVESLSKSPAKFNAQQLDYWQKQTVNQLPNDDFWEWAGSELQSQIPTDKADLFLTTVKPNASFPRDVAYWVNVCFGKTLNLETAQSELLRATGNRYFEEAFEAFKKFGKDLNSVVSHLKEKLNLKGKPLYQPLRIALTGAEHGPELAKLILIMDYETIQNRLQEACQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBX19_CHICK
Sequence: MADLGCKKPSDCTVSRLLSVVESELRAGRDKGDPTEKQLQVVLEDAPLWQRFREVTNEMIVTKNGRRMFPVLKISVSGLDPNAMYSFLLDFAPTDGHRWKYVNGEWVPAGKPEPPNHSCVYIHPDSPNFGAHWMKAAISFSKVKLTNKLNGSGQIMLNSLHKYEPQVHIVRVGGPHRMVMNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHPKDAPEAASEGQHMTYSHSPQAPHGCERYSALRGHRAAPYPPSYMQRNHSPTVNFFESSSNNLQVFSGHDSWTLPSSPHANLLSVPHTKGATSPGPSHYPCLWPVSNSAVSVTNPGSEVNSNTSSMFLRGNVPLPTASSSVQIPLQATVSGGMETQGEAPLVRLADSAWTSSHSF
What is the function of this protein?
May be involved in the initial formation of the chordamesoderm.
What are the official names of this protein?
T-box transcription factor TBX19.
What are the subcellular locations of this protein?
Nucleus.
Protein: NODI_NEOGA
Sequence: MGENMEREMLRPKTIAMDQNSASARSNPEREIKTGRLEPASNSAPTMAIDLQAVTMIYRDKTVVDSLSFGVRAGECFGLLGPNGAGKSTITRMLLGMATPSAGKISVLGLPVPGKARLARASIGVVSQFDNLDMEFTVRENLLVFGRYFQMSTRAIEKLIPSLLEFAQLEAKADVRVSDLSGGMKRRLTLARALVNDPQLLILDEPTTGLDPPARHQIWERLRSLLIRGKTILLTTHMMDEAERMCDRLCVLEGGRMIAEGPPLSLIEDIIGCPVIEVYGGNPDELSLIVRPHVDRIETSGETLFCYTVNSDQVRAKLREFPSLRLLERPANLEDVFLRLTGREMEK
What is the function of this protein?
Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction.  Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide.  This subunit is responsible for energy coupling to the transport system.
What are the official names of this protein?
Nod factor export ATP-binding protein I, Nodulation ATP-binding protein I.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipooligosaccharide exporter (TC 3.A.1.102) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IM30_PEA
Sequence: MTTKFQIFSGLPSAPLQPSSSLLKKPLATTLFGTRPVDTLKFRVMRIAKPVRGGGAIGVRMNLFDRFARVVKSYANALVSTFEDPEKILEQAVLEMNDDLTKMRQATAQVLASQKRLENKYKAAQQASEEWYRKAQLALQKGEEDLAREALKRRKSFADNASSLKAQLDQQKSVVDNLVSNTRLLESKIQEARSKKDTLKARAQSAKTATKVSEMLGNVNTSSALSAFEKMEEKVMTMESQAEALGQLTTDDLEGKFAMLETSSVDDDLANLKKELAGSSKKGELPPGRSSTTSTTSTKTGNPFRDADIEIELEQLRKRSKEL
What are the official names of this protein?
Membrane-associated 30 kDa protein, chloroplastic, M30.
What is the protein family that this protein belongs to?
Belongs to the PspA/IM30 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Peripheral membrane protein. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CH18_DROVI
Sequence: MMKFMCIFVCAIAAVSANAYGRQGYGSVPVGGYAYQVQPALTVKAIVPAGGYGGGSYGGGYGNNNYGRSIEVPVSAHYTSSRGYGAAPVDRQAISLAKLSLAAPNAGAPLVWKEPRQIVERSYGPQQSYGQKHSYGYGEQAQGASAAAASSSVAGQHSGYKNSGYKNSSY
What is the function of this protein?
Chorion membrane (egg shell) protein; plays a role in protecting the egg from the environment.
What are the official names of this protein?
Chorion protein S18.
What is the protein family that this protein belongs to?
Belongs to the chorion protein S15/S18 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAIE_ECOK1
Sequence: MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFRGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHAALHETQPLRQMEENRPRLQGTTDVTPKR
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: PKP1_HUMAN
Sequence: MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSSTLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF
What is the function of this protein?
Seems to play a role in junctional plaques.  Contributes to epidermal morphogenesis (PubMed:9326952).  May facilitate the formation of intermediate filaments (PubMed:10852826).
What are the official names of this protein?
Plakophilin-1, Band 6 protein, B6P.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Cell junction, desmosome. SUBCELLULAR LOCATION: Nucleus.
Protein: VPS53_MOUSE
Sequence: MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDQADFNAVEYINTLFPTEQSLANIDDVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWVKRQLVDYEEKYGRMFPREWCMTERISVEFCHVTRAELSKIMRARAKEIEVKLLLFAIQRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDETTPEMEELALEKGELEQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLSELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTSSSSGGLTISSLLKEKEGSEVARFTLEELCLICSILSTAEYCLATTQQLEEKLKEKVDVSLTERINLTGEMDTFSTVISSSIQLLVQDLDAACDPALIAMSKMPWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCIKFANSFIPKFITHLFKCKPISMVGAEQLLLDTHSLKMVLLDLPSIGSQVVRKAPASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLLTDCNSETFQKILDMKGLKRSEQSSMLELLRQRLPAPPSGTEGSSTLSLIAPTPEQESSRIRKLEKLIKKRL
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).  The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.  Acts as component of the EARP complex that is involved in endocytic recycling.  The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 53 homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS53 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex.
Protein: LPXH_TOLAT
Sequence: MTKLFIADLHLSESRPDLIQAFIHFLETEARTADELYILGDLFEFWIGDDEQSPLQQQITHALRTLANHGCQLFYSHGNRDFMIGKRFAQECGMTLLPPVYPCELAGEKALLLHGDQLCTDDEAYQRFRRITSWPWLQWIFLHLPLSRRVKIAQQIRQGSHKGKQQKSRSIMDVTPQSVITCFEQHKATLMIHGHTHRPQIHDVTLSSNQPARRIVLGDWDTDLWYLKIDDRDINLISQPINTAKN
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PEF1_SCHPO
Sequence: MNYQRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNIMSLSDVLQTENKLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTFSNEVVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEMATGRPLFAGSNNEDQLLKIFRLLGTPTEQSWPGISLLPEYKPTFPIYKAQDLAYLFPTFDPLGLDLLRRMLRLQPELRTTGQDALQHAWFLTA
What are the official names of this protein?
Serine/threonine-protein kinase pef1, Cyclin-dependent kinase pef1, PHO85 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: HAOX1_RAT
Sequence: MLPRLVCISDYEQHARTVLQKSVYDYYKSGANDQETLADNIRAFSRWKLYPRMLRNVADIDLSTSVLGQRVSMPICVGATAMQCMAHVDGELATVRACQTMGTGMMLSSWATSSIEEVAEAGPEALRWMQLYIYKDREVSSQLVKRAEQMGYKAIFVTVDTPYLGNRFDDVRNRFKLPPQLRMKNFETNDLAFSPKGNFGDNSGLAEYVAQAIDPSLSWDDIKWLRRLTSLPIVVKGILRGDDAQEAVKHGVDGILVSNHGARQLDGVPATIDALPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGARAVFVGRPIIWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLAVSKI
What is the function of this protein?
Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate.  The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine; this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones.  Can also catalyze the oxidation of glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate.  Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2.
What are the official names of this protein?
2-Hydroxyacid oxidase 1, HAOX1, Glycolate oxidase, GOX, Glyoxylate oxidase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: Y1733_MYCTU
Sequence: MIATTRDREGATMITFRLRLPCRTILRVFSRNPLVRGTDRLEAVVMLLAVTVSLLTIPFAAAAGTAVQDSRSHVYAHQAQTRHPATATVIDHEGVIDSNTTATSAPPRTKITVPARWVVNGIERSGEVNAKPGTKSGDRVGIWVDSAGQLVDEPAPPARAIADAALAALGLWLSVAAVAGALLALTRAILIRVRNASWQHDIDSLFCTQR
What are the official names of this protein?
Probable membrane protein Rv1733c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KCNJ5_MOUSE
Sequence: MAGDSRNAMNQDMEIGVTSQDHKKIPKQARDYIPIATDRTRLLTEGKKPRQRYMEKTGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTITWLFFGFIWWLIAYVRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINEKSPFWEMSRAQLEQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKRSGRLLQYLPSPPLLGGCAEAGNEAEAEKDEEGEPNGLSVSQATRGSM
What is the function of this protein?
This potassium channel is controlled by G proteins.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Can be blocked by external barium.
What are the official names of this protein?
G protein-activated inward rectifier potassium channel 4, GIRK-4, Cardiac inward rectifier, CIR, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, KATP-1, Potassium channel, inwardly rectifying subfamily J member 5.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: LEUD2_METKA
Sequence: MRWSGRAHVFGDDVDTDQIIPGRCLRRVSYDELGRYAMTGADPEFPEKVREGDVIVAGKNFGCGSSREQAVMALQQAGVACVVARSFARIFYRNAINRGLPTVEAEEDPTEVVEDGNRVTVDLDELVLRAGSEEVPLREPPEFALQAWREGGLLELVKKNPDKPPWRD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit 2, Alpha-IPM isomerase 2, IPMI 2, Isopropylmalate isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: DNLI_ANAD2
Sequence: MLLAELAEVSRAVAATPARLEKIARLAEALRRLAPDERAVGASWLAGDLPGGRIGIGGATVRAALDAAPAEGGGPGLTVAEVDAALGRIATASGAGSAGARRRELDALLARAGAPERWFLAALLLGELRQGALEGVLADAVARAAGLPAAEVRRAAMLAGALPPVAVAALSEGAAGLARFRLRVGEPVSPMLAQTAADVEEALRALGGEAALEWKLDGARIQAHRDGGEVRVFSRSLRDVTAAVPEVVALLRAAPEPRLVLDGEAIALRADGTPEPFQVTMRRFGRRLDVERLAPDLPLTAFFFDALVAGGAELLASPERVRWAALERAVPAEQRVPRLVTRDPAEAGAFLEDALARGQEGVVAKALDAPYEAGRRGAAWLKVKRAHTLDLVVLAAEWGSGRRRGWLSNLHLGARDPSTGGFVMLGKTFKGMTDAMLAWQTERLKALATGPLDAWQVPVRPELVVEVAFDGIQSSPRYPGGLALRFARVKRYREDKRPEDADTIETVRGLYGG
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
Probable DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: RRF_COXB1
Sequence: MINDIINDSKSRMEKSLGSLKTELAKLRTGRAHPSLLEHIKVDYYNVETPLSQVASIAIENPRTLSITPWEKNMVGPIEKAIQKADLGLNPATVGMVIRVPLPPLTEERRKELARVVREEAEHARVAIRNIRREANNDLKELMKEKEISEDEERRAQTAIQKLTDAQIAEVDKMASQKEADLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM4_HUMAN
Sequence: MTSFSTSAQCSTSDSACRISPGQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLATATTDAAQTLALAQDHSMDIPSQDQLKQSAEESSTSRKRTTEDDIPTLPTSEHKCIHSREDEDLIENLAQDETSRLDLGFEEWDVAGLPWWFLGNLRSNYTPRSNGSTDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEAADTEQTSEEVGKVSDKKVIEVGKNDDLEDSKSLSDDTDVEVTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSDITAIPEKENEGNDVPDCRRTISAPVVRPKDAYIKKENSKLFDPCNSVEFLDLAHSSESQETISSMGEQLDNLSEQRTDTENMEDCQNLLKPCSLCEKRPRDGNIIHGRTGHLVTCFHCARRLKKAGASCPICKKEIQLVIKVFIA
What is the function of this protein?
Along with MDM2, contributes to TP53 regulation (PubMed:32300648).  Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.  Inhibits degradation of MDM2.  Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
What are the official names of this protein?
Protein Mdm4, Double minute 4 protein, Mdm2-like p53-binding protein, Protein Mdmx, p53-binding protein Mdm4.
What is the protein family that this protein belongs to?
Belongs to the MDM2/MDM4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUD_YERPA
Sequence: MAKFIQHIGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFNDWRFLDDASKVPNPDFVLNLPRYQGATILLARENFGCGSSREHAPWALTDFGFKVVIAPSFADIFYGNAFNNQLLPVTLSEADIDTLFQLVKENEGIEFVVDLEQQTVNAGGKSYAFEIDPFRRHCMINGLDSIGLTLQHEHNISAYEKQQPEFLR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: FABP3_CAEEL
Sequence: MNLYLTLFSFCFLAIMAEAASEIPEKFFGKYDLDRSENFDEFLAAKGVSWFVRQMIKLAKVSKVLAKNETPGKYNMENLTSKKNTLYHGWELGKTFEAEGLDGVAHKITFSFKDGVLSEHHIRLNDPEHSAETYYYTIENDQLVMKMVNNGITCRRWFKRSTGKK
What is the function of this protein?
May play a role in sequestering potentially toxic fatty acids and their peroxidation products, or it may be involved in the maintenance of the impermeable lipid layer of the eggshell.
What are the official names of this protein?
Fatty acid-binding protein homolog 3, Lipid-binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Secreted. Note=From muscle into the perienteric fluid.
Protein: ATP6_BUCBP
Sequence: MNLEHNFNLPNYINHHLHHLQLNLSNLKFLNFNDNYIRNFWVCNFDSIFLSIFLGLVILISFFKISKTFTIQTPNKIQICIELIIDFINNNVKEIYHGKNKLIAPLSLTIFVWIFLMNLMDLIPIDLVPFIFQNFFETQIPIKLVPTTDVNITISMSLVVFLLIIFYSIKIKGIKGFLKDLFLQPFHNPIFFVFNFILESISLLSKPVSLGLRLFGNMYAGEMIFILISGLLPWWLQWILSVPWAIFHILIISLQSFIFMVLTIVYLSMASTKH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RR2_NEPOL
Sequence: MATLEQMLDVGVHFGHQARKWNPKMAPYIFGERKGIHILDILQTAILLDKARVYARRQAASNGSFLFVGTKNQAASIVRFAAERCQKNDRSQAHYVNHRWLGGMLTNWPTMQLCIKRLLELESNHERGGFQQFPKKEAAVARKQLARLEKHLGGVKNMTGLPTTVVIVGQPQEMNAVRECEKLGIPMITMLDSDCNPLLTDIGIPSNDDSIASIELVMREITKGIEEGQWIQKEGREEATIEIEWFVVEPTPVEKPLVIIEPPPVEKPVLSK
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSMF_SHIF8
Sequence: MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTTEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASWVKVLHANISRCGISNVALTHFGGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRPGGTLVYSTCTLNREENEAVCRWLKETYPDEVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPFSPVKDREAGQIRQAAASVGLNWDGNLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIAHASPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTSNA
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_VIBVY
Sequence: MKPILPDYNNAGVLIIGDVMLDRYWYGPTSRISPEAPVPVVKVENNEERPGGAANVAMNIASLGGHARIVGLTGMDEPAKVLTETLNSLKVKCDFVALPEYPTITKLRVMSRGQQLIRLDFEDKFEGTNPELVLTRMERALPHVQAVILSDYAKGALEHVEALIAKARAANVPVFIDPKGTNFEPYRGATLLTPNMSEFEAVVGKVTSDDDLVEKALGLIEKFELGALLVTRSEHGMTLVRPDQKPFHLPTQAKEVYDVTGAGDTVISVLAASVAAGKPLDEACALANAAAGVVVGKLGTSTLSTIELAEAIHGSRDTDFGVIAEAALIDAVKAAQAKGEKVVMTNGCFDILHAGHVSYLNNAAKLGDRLIVAVNTDESVKRLKGPGRPVNPTDRRMAVLAGLGAVDWVVPFSEDTPQRLISEVLPDLLVKGGDYKPEDIAGGKEVIAAGGEVKVLNFEDGCSTTEIIDAIKGGRG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RL1_THETH
Sequence: MPKHGKRYRALLEKVDPNKIYTIDEAAHLVKELATAKFDETVEVHAKLGIDPRRSDQNVRGTVSLPHGLGKQVRVLAIAKGEKIKEAEEAGADYVGGEEIIQKILDGWMDFDAVVATPDVMGAVGSKLGRILGPRGLLPNPKAGTVGFNIGEIIREIKAGRIEFRNDKTGAIHAPVGKASFPPEKLADNIRAFIRALEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.