PharMolix/UniProtQA huggingface dataset:
Protein: CLD8_MOUSE
Sequence: MATYALQMAALVLGGVGMVGTVAVTIMPQWRVSAFIESNIVVFENRWEGLWMNCMRHANIRMQCKVYDSLLALSPDLQASRGLMCAASVLAFLAFMTAILGMKCTRCTGDDENVKSRILLTAGIIFFITGLVVLIPVSWVANSIIRDFYNPLVDVALKRELGEALYIGWTTALVLIAGGALFCCVFCCTERSNSYRYSVPSHRTTQRSFHAEKRSPSIYSKSQYV
What is the function of this protein?
Tight-junction protein required for paracellular chloride transport in the kidney (PubMed:20921420, PubMed:25831548).  Mediates recruitment of CLDN4 to tight junction in the kidney (PubMed:20921420, PubMed:25831548).  Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-8.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: GPSB_STAES
Sequence: MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIITDYQKMADMNNEVVKLSEENHKLKKELEELRLRVATSRPQDNKNFSSNNSSSASNNVDILKRISNLEKAVFGK
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: NOP9_PENRW
Sequence: MPREQQKRGRRAEKKSQKEDSKRKFEETSEDPVAKRIKPSADDHETNEANDNIQLLENEDYIPLEQGEQQEGEQPDLDGDMPFYGLLDEEESEYFQRANEMLELNQFQDAEERSLFVDSVYSEANGKELKIACSQGCSRLMEKLISMSDARQLRRIFSKFIGHFLHLVQHRFASHCCETLFIHAAPAVMQKTKSQPKRSDEEGEEEPELSLADMFMAVIEELKENWGYLLTERFASHTIRVLLLVLAGEPVDVTSNESFVASRKKERIEIPTIQGEEKAGKSKAEKHTVPETFEPALKKIMTDMVAGLDDVYLRALATHPVGNPVLQVLLFLELSHFGKSSAKDPKSTIRRLVPDESFEEGSESAVFISGLLYDAVGSRLLETMVRYLPGKSFKNLYRNNLGDRIGSLSRNSTAGYVVLRMLERLGKDDLKIAMANINPEVPGLIERSRLIVPKMLIERCMVRGVDTKPLAEALEGAYSKDPAVRLQQMLKFNISENTAPQSEDHDMEEDNDGKDRKPRGPPPVSAAEKAEKLHASLLVQAMLTVPGPMSQLVYTSLLAQSSETIVQLAQEPTSSRVLQQALTSTTSTPQIRRQLTTRFQGYLTPLALSSSGSHVVDALWSATKDIFFVKERMAQELEQHEQELRDSFVGRAVWRNWSMDLFKRRRRDWTHKAKGFEERTEGNEGAERPKSKIEQARARYAAAKEAADAGATGANQTTVASR
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein nop9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: COAD_SALDC
Sequence: MQKRAIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPGKKPMFTLDERVALAQKATAHLGNVEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQLAHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPDNVHQALMDKLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_RHOE4
Sequence: MARVKRAVNAQKKRRSILAASSGYRGQRSRLYTKAKEQQLHSLTYAYRDRRARKGEFRKLWITRINAAARANDITYNRLIQGLRLAEVEVDRKILAELAVSDAEAFAGLVALAKAALPADVNAPAGEAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ACYP_SYNR3
Sequence: MAKRLERDGQPNRSLRIPAERWRFRIRGLVQGVGYRAGCCRRAQELGLAGWVRNCSDGSVEVQAEGDEQRLTELRVWCEGGPPGARVDSVDGSRVATTGADWFEIRPNHFQGGALTR
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: GATA_PSEAB
Sequence: MLHQLTLAEIARALADKQFSAEELTRTLLGRIRQLDPQLNSFISITDDLAIAQAKAADERRANGENGALLGAPIAHKDLFCTQGVRTSCGSKMLDNFVSPYDATVVEKLAAAGAVTLGKLNMDEFAMGSSNQSSHYGAVNNPWSLDRVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVEQPVDDYLAALQKPLSGLRIGLPREYFGAGLDSRIADAVLAVVEELKTLGATVKDISLPNMQHAIPAYYVIAPAEASSNLSRFDGVRYGYRCDAPQNLEDLYKRSRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFVSAFAEVDVILGPTTPNPAWKIGEKNDDPVSQYLEDIYTITANLAGLPGLSMPAGFVDGLPVGVQLLAPYFQEGRLLNVAHQYQQVSDWHTRTPAGF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: TRI35_MOUSE
Sequence: MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPSCPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCLEDKELLCCACQADARHQEHRVQPIKDTAQDFRAKCKNMEHVLREKAKAFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATLDAMKEESRKKHLQAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPTWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAHFGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI
What is the function of this protein?
E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response (By similarity) (PubMed:32562145).  Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via RIG-I signaling pathway.  Can also catalyze 'Lys-48'-linked polyubiquitination and proteasomal degradation of viral proteins such as influenza virus PB2.  Acts as a negative feedback regulator of TLR7- and TLR9-triggered signaling.  Mechanistically, promotes the 'Lys-48'-linked ubiquitination of IRF7 and induces its degradation via a proteasome-dependent pathway.  Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM35, Hemopoietic lineage switch protein 5, Macrophage-derived apoptosis-inducing RBCC protein, Protein MAIR, Protein Nc8.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies in transfected COS and HeLa cells.
Protein: SUVH7_ARATH
Sequence: MDKSIPIKAIPVACVRPDLVDDVTKNTSTIPTMVSPVLTNMPSATSPLLMVPPLRTIWPSNKEWYDGDAGPSSTGPIKREASDNTNDTAHNTFAPPPEMVIPLITIRPSDDSSNYSCDAGAGPSTGPVKRGRGRPKGSKNSTPTEPKKPKVYDPNSLKVTSRGNFDSEITEAETETGNQEIVDSVMMRFDAVRRRLCQINHPEDILTTASGNCTKMGVKTNTRRRIGAVPGIHVGDIFYYWGEMCLVGLHKSNYGGIDFFTAAESAVEGHAAMCVVTAGQYDGETEGLDTLIYSGQGGTDVYGNARDQEMKGGNLALEASVSKGNDVRVVRGVIHPHENNQKIYIYDGMYLVSKFWTVTGKSGFKEFRFKLVRKPNQPPAYAIWKTVENLRNHDLIDSRQGFILEDLSFGAELLRVPLVNEVDEDDKTIPEDFDYIPSQCHSGMMTHEFHFDRQSLGCQNCRHQPCMHQNCTCVQRNGDLLPYHNNILVCRKPLIYECGGSCPCPDHCPTRLVQTGLKLHLEVFKTRNCGWGLRSWDPIRAGTFICEFAGLRKTKEEVEEDDDYLFDTSKIYQRFRWNYEPELLLEDSWEQVSEFINLPTQVLISAKEKGNVGRFMNHSCSPNVFWQPIEYENRGDVYLLIGLFAMKHIPPMTELTYDYGVSCVERSEEDEVLLYKGKKTCLCGSVKCRGSFT
What is the function of this protein?
Histone methyltransferase.  Methylates 'Lys-9' of histone H3.  H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH7, Histone H3-K9 methyltransferase 7, H3-K9-HMTase 7, Protein SET DOMAIN GROUP 17, Suppressor of variegation 3-9 homolog protein 7, Su(var)3-9 homolog protein 7.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associates with centromeric constitutive heterochromatin.
Protein: SPED_HELMI
Sequence: MEIKSIKKLKLYGFNNLTKTLSFNMYDICYAKTPEHRKAYIEYIDEEYNSERLTNILIEVANIIGANILNIAKQDYDPQGASVTMLISEGKVEQDVENGQGNGNAIGSATDCDNGDGKAGEDCALLIPNAVAAHLDKSHITVHTYPESHPDKGISTFRADIDVSTCGMISPLKALNYLINSFSSDIVIADYRVRGFTRDVSGKKYFIDHKINSIQNYIAKETRELYQMIDVNVYQDNIFHTKMLLKEFDLDNYLFGTAKKELLPGEKKKIKQRLKKEMYEIFSGRNIPKV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: GATD_SULIA
Sequence: MQENYKAKAYDILKNLNIEEGDLIEIKKGDLRIRGVLLPSYSKDERIFVIKLDNGYNIGISIDNISEIKLITKNSSKAQESERKEVSRNGAKSEIKIISTGGTIVSKVEYETGAVRPALTTEEIVQFLPEINEIAKVDAEVLFSILSENMKPEYWVKIAESVKKAFDEGNTGVVIAHGTDTMAYTASALAFSLRSLQGPVVLVGSQRSSDRPSSDSAINLLSAVTTAKYAPFGEVVVNMHADSSDTYALVHRGVKVRKMHSSRRDAFQSVNDKPLAKVLWKERKLVMLDKSYMSKKGETTLDAKFDNRAFLLYYYPGLDRDFLEHILTNTKIRGLIIAGTGLGHTSSDYVELFRKATKDGIFIGMTTQCLFGRVNMNVYTTGRQLLDAGVTPLEDMLPEVALVKLMWVLAHEQDLEKIRSLMISNLVGEINPRHTLDLFPRWSYE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit D, Glu-ADT subunit D.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family. GatD subfamily.
Protein: PYY_BERRH
Sequence: YPPKPENPGDDAAPEELAKYYSALRHYINLITRQRY
What are the official names of this protein?
Peptide YY-like, PYY.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: VG39_BPML5
Sequence: MITADEQDHEFFDILYQQWAKSTGAEKTYWMPEEVEPPSICETDHGLEDHVIWAVNQETQDKDLVASHLSEADADFICGLHGAIPDLIRRLHEAIDEATSKDEARDRAEANLAEAYLENQGLQERIRELESELSYWSNR
What are the official names of this protein?
Gene 39 protein, Gp39.
Protein: LIPC_RAT
Sequence: MGNHLQISVSLVLCIFIQSSACGQGVGTEPFGRNLGATEERKPLQKPEIRFLLFKDESDRLGCQLRPQHPETLQECGFNSSHPLVMIIHGWSVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISLAYQHYAIAVRNTRVVGQEVAALLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTINCAHERSVHLFIDSLQHSNLQNTGFQCSNMDSFSQGLCLNCKKGRCNSLGYDIRRIGHVKSKTLFLITRAQSPFKVYHYQFKIQFINQMEKPMEPTFTMTLLGTKEEIKKIPITLGEGITSNKTYSLLITLNKDIGELIMLKFKWENSAVWANVWNTVQTIMLWDTEPHYAGLIVKTIWVKAGETQQRMTFCPDNVDDLQLHPTQEKVFVKCDLKSKD
What is the function of this protein?
Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles (PubMed:7074125, PubMed:6747460, PubMed:1770315, PubMed:1865764, PubMed:1531641).  Also exhibits lysophospholipase activity (PubMed:1531641).  Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates (PubMed:1865764).  In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position (By similarity).
What are the official names of this protein?
Hepatic triacylglycerol lipase, HL, Hepatic lipase, Lipase member C, Lysophospholipase, Phospholipase A1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS3_PSELT
Sequence: MGQKVHPRGFRLGVSADWQTRWFNEKNYATWLKEDEEIRKVVKNAYSQAGISEVFIERPDNESVTITIKTARPGVIIGKKGAEIGKLREDLEKELNRRVIVNVEEIKTPETDAQLVAENIAGRIEKRASYKRAMKRALSDALRKGATGVKVMVSGRLAGAEIARREWYLRGRLPLQTVRAVVDYGTATAKTKYGTIGIKVWIYKGDAEV
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: YV008_HUMAN
Sequence: MSHSRRAAPTQDQCHTPGFPTSRETSGSIWQARICGSLQALDTWRTHIPRKSPAPTQASQICLLLPESPWRNPTPRGFLKPLINWDAILYFKEKRNIQVTTQAHPQNQASCSSQEVATPGLVPQAAAPKVYERSHDNLNAEAQGLAGAQVSKPQNPITRLCSLKEQSILKIFTKQSI
What are the official names of this protein?
Putative uncharacterized protein FLJ32756.
Protein: CHS1_AJECA
Sequence: DFLFARTMIGVFKNIEYMCSRTNSKTWGKEAWKKIVVCVVSDGRAKINPRTRAVLAGLGVYQDGIAKQQVNGKDVTAHIYEYTTQIGMELKGNQVHLKPRSGVPVQMIFCLKEKNQKKINSHRWFFQAFGRVLDPNICVLLDAGTKPGRDSIYHLWRAFDLQPMCGGACGEIKAMLSHGKKLINPLIXA
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 1, Chitin-UDP acetyl-glucosaminyl transferase 1, Class-I chitin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family. Class I subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS20_AZOC5
Sequence: MANTPSAKKAARKIERRTAVNRARRSRVRTYLRKLEDALTAGNKDAAVAAFKAAEPEIMRAVTKGVLHKNTASRKVSRLAARVRKISA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RRF_FERNB
Sequence: MVNSFIKTTEEKMKKSVEKIAEELKHLRTGRATPAVLEEIKIDYYGVPTPVLQVAQVTTEERQLVIKPWERNLLNVIEKAILASDLGLTPVNDGTVVRINFPTPTTEQRQKWVKKAKEIVEEGKVAVRNIRRDILKDIKDKKKAGEISEDDEKRLEKEIQNLTDKYVAELDKLFEKKEKEIMEF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSX1_DAUMA
Sequence: MTSLPLGVKVEDSAFGKPAGGGEGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHRKPGAKESALAASEGAQAAGGSAQPLGVRPGSLGAPDAPSSPRPLGHFSVGGLLKLPEDALVKAESPEKPERTPWMQSPRFSPPPARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPPAAFGLSFPLGGPAAVAAAAGASLYGASGPFQRAALPVAPVGLYTAHVGYSMYHLT
What is the function of this protein?
Acts as a transcriptional repressor.  May play a role in limb-pattern formation.  Acts in cranofacial development and specifically in odontogenesis (By similarity).
What are the official names of this protein?
Homeobox protein MSX-1, Msh homeobox 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the Msh homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEC1_BOVIN
Sequence: MWDMRAVAPQRPAAGHPRAGWPRKLKTAATRFWATCPSSSTVCFLFVIFAVSTVFHCHRRLALVPAPWAYAGHVVLFPRHLPRGGVFTINAKGRLGNQMGEYATLYALAKMNGRAAFIPPQMHSTLAPIFRITLPVLHDATARSVPWQNYHLNDWMEEQYRHIPGEYVRLTGYPCSWTFYHHLRAEILQEFTLHAHVREEAQNFLRGLRVNGSRPSTYVGVHVRRGDYVRVMPTMWKGVLADRGYLQQALDWFRARHHSPLFVITSDDMAWCRRNINSSHRDVVFAGSGQQGSPARDFALLTQCNHTVITVGTFGIWAAYLAGGSTVYLANFTLPGSRFRMIFKPQAAFLPEWVGIAANLGQARESHP
What is the function of this protein?
Catalyzes the transfer of alpha 1,2-linked fucose to ganglioside GM1 and galacto-N-biose.
What are the official names of this protein?
Galactoside 2-alpha-L-fucosyltransferase SEC1, Secretory blood group protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: PRSR2_MOUSE
Sequence: MPGNQQKPESLETDSDTSPSCGLSDLSRGGSLESRCSSSRSRSFTMDDESLKHLTHEEKDVILFFEETLDSLEYDFDEPALCDSGIHCHSPQSLEESPSSHSEPEDVIDLVQPAPASGEAESLPDMPQVTGAPSDTKHGTPFLEGGKQAAENSLPPPDSRGPEVFPLPPSLPVPAPSAPRKELMSPSPPAEHPKLLRSVPTPLVIAQKISEKLAGNEALSPTSPSKEGRPGEWRTPTSPASRNGDHVGVWHRHTTQSAPKVHRFPSNISVTNSAGKDFNKTISKAAVNVQERKAQVLANINGMSFIAAGDTSSEERWQKAEEQRSGSADGARTLGRAGMAGEPGAPCAGVPARAQQSRAVQTEQPPALANGFQSVHEALRSEPSSFVPTSKTITFRPDPAVTGKLARQNASRSLYEPRPDGSQDARKRTGSLPRAVGFRPQGITVQFSGRGSTEEARREALRKLGLLKENL
What are the official names of this protein?
Proline and serine-rich protein 2.
Protein: LEP1_SYNY3
Sequence: MQNSPIPSPWQFIKENIPLLMVALVLALLLRFFVAEPRYIPSDSMLPTLEQGDRLVVEKVSYHFHPPQVGDIIVFHPPELLQVQGYDLGQAFIKRVIALPGQTVEVNNGIVYRDGQPLQEEYILEPPQYNLPAVRVPDGQVFVMGDNRNNSNDSHVWGFLPQQNIIGHALFRFFPASRWGQLGSFTFVPARTIINT
What are the official names of this protein?
Probable signal peptidase I-1, SPase I-1, Leader peptidase I-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: CFA68_MOUSE
Sequence: MAVSCSLNHSTYLQRQNLVCYLRNPHYGSLIYADGHGEVWTDWNDMSKFLQYGWRCTTNENSYSNRTLVGNWNQERYDLKNIVKPKPLPSQFGHAFETTYDANYSRKKPQSTHRFKREPHWFPGHQPELDPPHYKCTAKSTYMTNYSEPQPTHYSCCVYDPSVSQS
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Cilia- and flagella-associated protein 68.
What is the protein family that this protein belongs to?
Belongs to the CFAP68 family.
Protein: RNC_GEOTN
Sequence: MSKQRDKGRIYEKRRAKFQELQKKIGITFQNEKLLIQAFTHSSYVNEHRRRFHEDNERLEFLGDAVLELTVSQYLFQKFPHMSEGQLTKLRAAIVCEPSLVKFANALSFGELVLLGKGEELTGGRTRPALLADVFEAFIGALYLDQGMDVVLRFLGQTMFPKIDEGAFSHVMDFKSQLQELVQRDGSGTLEYAILEEKGPAHNKEFVARVALNGQELGVGVGRSKKEAEQHAAQMALETLRAADKQ
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIRB6_BRUA2
Sequence: MVNPVIFEFIGTSIHNQLNNYVTMVASNTMNMIATTAVLAGGLYYTAMGILMSVGRIEGPFSQLVISCIKFMLIAAFALNISTYSEWVIDTVHNMESGFADAFAGNHGTPSSTIYQTLDNSLGKGWNIAAMLFEKGDNRGLTQIVQGFSELLLSFLVAGSTLILAGPTGAMIVATNAVIAILLGIGPLFILALGWAPTRGFFDRWFGAIVTSILQVALLSAVLSISSAIFSRMVAAINLASATQSTLFSCLSLTAVTIVMPYMMYKVYEYGGILGSSISAATISLGSLAVNTATSGGGAMTSIFSGSSGGGGSGSAKAGGESSYSAGGNAMWSPAYRQHVLGQFNRD
What is the function of this protein?
The virB operon is essential for intracellular survival and is not involved in the invasion process.  Constitutes a major determinant of virulence in mice.
What are the official names of this protein?
Type IV secretion system protein VirB6.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: B1_FHV
Sequence: MLNDAKQTRANPGTSRPHSNGGGSSHGNELPRRTEQRAQGPRQPARLPKQGKTNGKSDGNITAGETQRGGIPRGKGPRGGKTNTRRTPPKAGAQPQPSNNRK
What is the function of this protein?
Not known.  Encoded on a subgenomic RNA (RNA3) synthesized during replication and which is co-terminal with RNA1.
What are the official names of this protein?
Protein B1.
Protein: TAM_MYCTA
Sequence: MWDPDVYLAFSGHRNRPFYELVSRVGLERARRVVDLGCGPGHLTRYLARRWPGAVIEALDSSPEMVAAAAERGIDATTGDLRDWKPKPDTDVVVSNAALHWVPEHSDLLVRWVDELAPGSWIAVQIPGNFETPSHAAVRALARREPYAKLMRDIPFRVGAVVQSPAYYAELLMDTGCKVDVWETTYLHQLTGEHPVLDWITGSALVPVRERLSDESWQQFRQELIPLLNDAYPPRADGSTIFPFRRLFMVAEVGGARRSGG
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABHDD_XENLA
Sequence: MEKHWVLWSCAERWLLALASWSWGLCRICLLPLILTFNMYGGVILLLLIFVSIAGILFKFQDVLLYFPDQPSSSRLYIPMPTGIPHENIFIKTKDNIRLNLILLRYTGDNSSFSPTIIYFHGNAGNIGHRLPNALLMLVNLKVNLILVDYRGYGKSDGEPSEEGLYMDSEAVLDYVMTRPDIDKTKIILFGRSLGGAVAIHLASENAHRICALVLENTFLSIPHMASTLFSVLPMRYLPLWCYKNKFLSYRKIVQCRMPSLFISGLSDQLIPPFMMKQLYELSPSRTKRLAIFPDGTHNDTWQCQGYFTALEQFIKELNSNHCPEANAKTSNVTII
What are the official names of this protein?
Protein ABHD13, Alpha/beta hydrolase domain-containing protein 13, Abhydrolase domain-containing protein 13.
What is the protein family that this protein belongs to?
Belongs to the serine esterase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: JZT34_CHIGU
Sequence: MKVLVLITLAVLGAMFVWTSAAELEERGSDQRDSPAWVKSMERIFQSEERACREWLGGCSKDADCCAHLECRKKWPYHCVWDWTVRK
What is the function of this protein?
Potent and selective inhibitor of hNav1. 7/SCN9A (IC(50)=610 nM) (PubMed:29393892).  Also shows a weak activity towards Nav1. 3/SCN3A (IC(50)=7950 nM) (PubMed:29393892).  In addition, inhibits voltage-gated potassium channels (Kv) in rat DRG neurons (PubMed:18581053).  It does not alter the voltage dependence of activation, but it causes a small hyperpolarizing shift in the steady-state inactivations of Nav1. 7/SNC9A (PubMed:29393892).  Chimera experiments show that the toxin binds to the DIIS3-S4 linker (site 4) of Nav1. 7/SCN9A, whereas Nav1. 7/SCN9A Asp-827 residue is shown by substitution experiments to be critical for its sensitivity (PubMed:19463735, PubMed:29393892).  The toxin traps the domain II voltage sensor in the closed configuration, and not in an outward position (PubMed:29393892).  In vivo, shows analgesic activity in three rodent pain models (formalin-induced, acid-induced, and thermal) (PubMed:29393892).
What are the official names of this protein?
Mu-theraphotoxin-Cg1a, Mu-TRTX-Cg1a, Jingzhaotoxin-34, JZTX-34, Peptide F6-25.51.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 39 (Jztx-34) subfamily.
What are the subcellular locations of this protein?
Secreted.