PharMolix/UniProtQA huggingface dataset:
Protein: MGSA_SALA4
Sequence: MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYATGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: METE_YEAST
Sequence: MVQSAVLGFPRIGPNRELKKATEGYWNGKITVDELFKVGKDLRTQNWKLQKEAGVDIIPSNDFSFYDQVLDLSLLFNVIPDRYTKYDLSPIDTLFAMGRGLQRKATETEKAVDVTALEMVKWFDSNYHYVRPTFSKTTQFKLNGQKPVDEFLEAKELGIHTRPVLLGPVSYLFLGKADKDSLDLEPLSLLEQLLPLYTEILSKLASAGATEVQIDEPVLVLDLPANAQAAIKKAYTYFGEQSNLPKITLATYFGTVVPNLDAIKGLPVAALHVDFVRAPEQFDEVVAAIGNKQTLSVGIVDGRNIWKNDFKKSSAIVNKAIEKLGADRVVVATSSSLLHTPVDLNNETKLDAEIKGFFSFATQKLDEVVVITKNVSGQDVAAALEANAKSVESRGKSKFIHDAAVKARVASIDEKMSTRAAPFEQRLPEQQKVFNLPLFPTTTIGSFPQTKDIRINRNKFNKGTISAEEYEKFINSEIEKVIRFQEEIGLDVLVHGEPERNDMVQYFGEQINGYAFTVNGWVQSYGSRYVRPPIIVGDLSRPKAMSVKESVYAQSITSKPVKGMLTGPITCLRWSFPRDDVDQKTQAMQLALALRDEVNDLEAAGIKVIQVDEPALREGLPLREGTERSAYYTWAAEAFRVATSGVANKTQIHSHFCYSDLDPNHIKALDADVVSIEFSKKDDANYIAEFKNYPNHIGLGLFDIHSPRIPSKDEFIAKISTILKSYPAEKFWVNPDCGLKTRGWEETRLSLTHMVEAAKYFREQYKN
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Delta-P8 protein, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: AMPA_RHOP5
Sequence: MSDVVSVGFVPMSTSAKGLLVVFCDETLASGPDSRKALGTAVDAVKRAAETSRFKGKSGAALDILAPEGLKASRLVVIGIGKPADLKEHDFLKLGGTIASKLGSGKEAVTVIAELPAGPMSPAQAAALAAGVRLRAYKFDRYKTKKKDDDAPLDASVAIAVRDVAATKKAFAPQNGLVDGVNIARELVNEPPNVLYPAEFARRASQLSKLGVGIEVLDVPAMTKLKMGALLGVAQGSARPARTVIMRWNGGKKGAAPIAFVGKGVCFDTGGISIKPSASMEDMKGDMGGAACVVGLMHALAARKAKVNVIGAIGLVENMPDGNAQRPGDIVTSMSGQTIEIINTDAEGRLVLADVLWYVAKKHKPKFMVDLATLTGAIMVALGTEYAGLFSNNDELATRLNEVGLATGERVWRMPLGPEYDKQIDSQFADMKNTGSRNGGSITAAQFLQRFVDDTPWAHLDIAGTAMASPKSDINQSWGSGYGVRLLDRLVATHYESK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTPV_MYCTU
Sequence: MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSAGVRGVGVVRKITGGIRRMLSRPPGVDKPLKASRCGGRPRGPVRGSASWPGEQNRRERRTWLPRVWLALPLGLLALGSSMFFGAYPWAGWLAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLTAFVYSTYQLFAGGPLFFDTSALIIAFVVLGRHLEARATGKASEAISKLLELGAKEATLLVDGQELLVPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFVPAVIGVAVATFAGWTLIAANPVAGMTAAVAVLIIACPCALGLATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQRRQPDQVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAKQVGIEKVLAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYNTAAIPLAALGALNPVVAGAAMGFSSVSVVTNSLRLRRFGRDGRTA
What is the function of this protein?
Necessary for copper homeostasis and likely functions as a copper exporter.  Also required for full virulence.
What are the official names of this protein?
Probable copper-exporting P-type ATPase V, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATC_BORBR
Sequence: MALNEQDVARIARLARIELTPDQRGRAQAELNGILHLIERLQAVDTQGVEPLAHPLSAHEDITLRLREDAVSEQATEASRAELLANAPESADGLFLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: COFC_HALLT
Sequence: MEVIVPFSTERPKSRLSAVLTPDERAAFARTMLQDVLAAIDAADGEPRILATGAVGIDLPSPVEIDDRPLTDAVNAAIDARLGNDGAERVAVVMADLALATPNALRELFAAGREAEVAIAPGRGGGTNAFVAGHPAFRVDYHGASYLDHRRIADEIGAGVRVVDSHRLATDVDEPADLAELLIHAEADGDGGRAARWLRDAGFALDTTDGRVGVRRE
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
2-phospho-L-lactate guanylyltransferase, LP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: EXBB_HELPJ
Sequence: MGGFSMAMLKDYVDVFVFAVLGVASFLALWFVIERVIFYSKVDLKAYDDIDALNLDLTKNLTILYVIFSNAPYVGLLGTVLGIMVIFYDMGVSGGMDAKTIMVGLSLALKATALGLAVAIPTLIAYNSLLRKSDVLSEKFRIMKT
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.  Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
What are the official names of this protein?
Biopolymer transport protein ExbB.
What is the protein family that this protein belongs to?
Belongs to the ExbB/TolQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSGA_ECOLC
Sequence: MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIVISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHERTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLNKIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDISDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLWHLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILESMAQVKTRKNFSDTDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_SALG2
Sequence: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGFDSPYVPGWDCHGLPIELKVEQEFGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGRIIKNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFRAVDQDAVKAKFGLPGVSGPVSLVIWTTTPWTLPANRAISLAPDFDYALVQIDGQAVILAKDLVESVMQRIGAAEYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGAYLPGTYPTLDGVNVFKANDIVIELLKEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDKEGLRQQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKETQELLPIERTLAAMEEVAKRVEVDGIQAWWDLDPKEILGEDADQYEKVPDTLDVWFDSGSTSYSVVDARPEFAGHAADMYLEGSDQHRGWFMSSLMISVAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFNPATDMVKPEEMVVLDRWAVGCAKTAQQEILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPIMSFTADEIWGYLPGEREKYVFTGEWYDGLFGLEENEEFNDAFWDDVRYIKDQVNKELENQKANGIKSNLEAKVTLKYADDANGTIKKLKLLGEEVRFIFITSQFVISEQAGGIDDENIQYNAGNTTVQAVVTRAEGDKCPRCWHYTTDVGKVAEHADICGRCVSNIAGNGEQRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSAA_ECOL6
Sequence: MELYLDTSDVVAVTALSRIFPLAGVTTNPSIIAAGKKPLEVVLPQLHEAMGGQGRLFAQVMATTAEGMVNDARKLRSIIADIVVKVPVTAEGLAAIKMLKAEGIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQAKVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWLGAFGRTSI
What is the function of this protein?
Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
What are the official names of this protein?
Fructose-6-phosphate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR1_ECOLI
Sequence: MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHFARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSPLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYVD
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  Provides the D-alanine required for cell wall biosynthesis.
What are the official names of this protein?
Alanine racemase, biosynthetic.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: MDHM_CAPAA
Sequence: DDLFNINAGIVKLFGVTTLDVVRTQDGGTEVVEAK
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: URTF_STAHJ
Sequence: MLDQNQLKKYNQEHLSEYEKLMSSNEKEKLESKVNELDLESIQQLFQDLYVNRQSISDVSSVSEVKYQRKTELTDQEGAKYEQKGIEAIRNGEFAVLLMAGGQGTRLGYKGPKGSFEIKGVSLFELQARQLLKLKKETGHLINWYIMTSDINHEETLSYFEQHDYFGYNPDNVHFFKQENMVALCETGQLVLNEQGYIMETPNGNGGVFKSLEKNGYLDKMASDGVKFIFLNNIDNVLVKVLDPLFAGFTVVNDCDVTSKSIQPKDGESVGRLVNQNSKDTVLEYSELDEAVANTFDNANIGIHAFKVAFIKQAVNNDLPYHLAVKKLKQLDEDFGVVEKPTLKFELFYFDIFRYATSFVTLQVNREDEFSPLKNKEGKDSVETATSDLERLNLI
What are the official names of this protein?
Probable uridylyltransferase SH0870.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 1 family.
Protein: S38A5_HUMAN
Sequence: MELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQFMDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQALCFGVLGVLFMAVSLGFMFANWATGQSRMSGH
What is the function of this protein?
Symporter that cotransports neutral amino acids and sodium ions, coupled to an H(+) antiporter activity (PubMed:11243884).  Releases L-glutamine and glycine from astroglial cells and may participate in the glutamate/GABA-L-glutamine cycle and the NMDA receptors activation (By similarity).  In addition, contributes significantly to L-glutamine uptake in retina, namely in ganglion and Mueller cells therefore, participates in the retinal glutamate-glutamine cycle (By similarity).  The transport activity is pH sensitive and Li(+) tolerant (PubMed:11243884).  Moreover functions in both direction and is associated with large uncoupled fluxes of protons (By similarity).  The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+) (By similarity).  May have a particular importance for modulation of net hepatic glutamine flux (By similarity).
What are the official names of this protein?
Sodium-coupled neutral amino acid transporter 5, Solute carrier family 38 member 5, System N transporter 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
Protein: AROB_SHEB8
Sequence: MKQIQVNLGVRSYPIYIGQNLMSDGETLSRYLLKKRILIVTNETVAPLYLKQIQETMASFGEVESVILPDGEQFKDLAHLDTIFTALLQQNYGRDSVLVALGGGVIGDMTGFAAACYQRGIDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQIVLIDTLCLHTLPAREFAAGMAEVIKYGIMWDADFFQWLEDNVTTLKTLDAQALVYAISRCCEIKADVVSQDETEQGVRALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVLAAQTAKALGLIDESIVCRIIQLLQAFDLPVSAPESMDFDSFIQHMRRDKKVLGGQIRLVLPTAIGRADVFSQVTESTLEQVIRCA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_BORPD
Sequence: MSASLKRTPLADAHVAAGARMVDFGGWDMPLAYGSQLEEHHAVRRDAGMFDVSHMLNVDVTGPDATAFLRRLVANDVARLTVPGKALYSCMLNPQGGIIDDLIVYFFAADQWRVVVNAATADKDVAWMQRVAAAGSYDVAIAPRRDLAMVAVQGPNARARVWAARPAWQAATEPLTPFVAAQVADDTLVARTGYTGEDGFEIVLPADQVVALWNDLLAQGVRPCGLGARDTLRLEAGMNLYGQDMDELTQPDQAGLTWTVSLKDPERRFVGRDALEQFAAPRGFVGLKLQERGVMRAHMAVYTPLGEGEITSGTMSPTLGVSVAFARVPQGVQPGQTVEVDIRGKRVPALVCKLPFVRHGKAVEHS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RS23_HUMAN
Sequence: MGKCRGLRTARKLRSHRRDQKWHDKQYKKAHLGTALKANPFGGASHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFIEENDEVLVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKGKKERPRS
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:28257692, PubMed:23636399, PubMed:25957688, PubMed:25901680).  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (PubMed:23636399, PubMed:25957688, PubMed:25901680).  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (PubMed:23636399, PubMed:25957688, PubMed:25901680).  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:23636399, PubMed:25957688, PubMed:25901680).  Plays an important role in translational accuracy (PubMed:28257692).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
40S ribosomal protein S23, Small ribosomal subunit protein uS12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: CCPA_STAAS
Sequence: MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLARGLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNIDFTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAILCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPHRIEYRGTTK
What is the function of this protein?
Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.
What are the official names of this protein?
Catabolite control protein A.
Protein: EF2_METJA
Sequence: MGKRAKMIAKIKELMEKYDRIRNIGICAHIDHGKTTLSDNLLAGAGMISKELAGEQLALDFDEEEAQRGITIFAANVSMVHTYEGNEYLINLIDTPGHVDFGGDVTRAMRAIDGAIVVVCAVEGVMPQTETVLRQALRERVKPVLFINKVDRLINELKLTPEELQSRFIKIINDINNLIRKMAPEEFKDKWLVRVEDGSVAFGSAYNNWAISVPFMKKSGITFKDIIKYCEEDRQDELAEKAPLHEVVLDMVIKHLPSPPEAQKYRIPHLWKGDLNSEAGKAMLNCDPNGPLAGVITKIIVDKHAGAVSVCRLFSGRIKQGDEVYMVNNQQKAKIQQVSVFMGPERIPVDSISAGNICALVGLKEASAGETICSPDKIIEPFEAITHISEPVITVAIEAKNTKDLPKLIEVLRQVAREDPTVKVEINEETGEHLLSGMGELHIEIITKLKIERDAGIPVEVGQPIVVYRETVTGQSPVVESKSPNKHNKLYFVVEPLEESVLQAYKEGRIPDVDTKRKLDDKIVQELIKAGMDPEEAKRVMCIYEGNVLINMTRGIVHLDEVKELIIQGFKEAMRNGPLAAEKCQGVKVKLMDAVLHEDAIHRGPAQMIPAARFGIRDAMMQANPVLLEPMQFVYINTPQDFMGAAMREISNRRGQILDMEQEGDMAIIKAKCPVAEMFGFAGAIRGATQGRCLWSIEFAGYEKVPRDMQEQLIKQIRERKGLKLE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_DECAR
Sequence: MARVTVDDCLKRIPNRFQMTLAAAHRARQLANGATPLVDPEKHKPTVVALKEMGAGKVGLEVLNRGQA
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SERC_BURM1
Sequence: MRVFNFSAGPAALPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALADLRELLDVPASHRVLFLQGGGIAENAIVPMNLLGSRKTADFVVTGSWSQKSFNEAKKYCTPHLAATGKTDAGFTRAPAFAEWQLSDDPAYVHLCTNETIDGVETFEIPDLGDVPLVADVSSHILSRPMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTVAANNSLYNTPPTYAIYIAGLVFQWLKRQGGLGAIEARNIEKAKLLYDTIDGSSFYLNKVEPAVRSRMNVPFFLADESRNEDFLAGAKARGLLQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRCA
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_ARTS2
Sequence: MQLQVARIGKPHGIRGEVTVQVLTDAPEDRFIPGTRFVVEPASAGPLTVDSARWNKDILLLGFEGIETRNQAEALRGAKLFIETEELEEEDDEGWYEHELVGLDVRVGDAVVGTISGLRTLPVQDLIVVESPDGKEILIPFVEEIVPEVNVGEKYILVTPPPGLFEINVEDSGETSDAGESGPGEAEPGKAEAGDNA
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTR2_BOVIN
Sequence: MTEDKVTGTLVLAVFTAVLSSFQFGYDIGVINAPQQVIITHYRHVLGVSLDDRIAINNYALNSTEELPTSLGDPTPVSWAEEETMTSASLITMFWSLSVSSFAVGGMIASFFGGLLGDKLGRIKALLVANILSLVGALLMGFSKLGPSHILIISGRGISGLYCGLISGLIPMYIGEIAPTTLRGAIGALHQLAIVTGILISQIVGLDFILGNHELWHILLGLSAVPAILQCLLLFFCPESPRYLYIKLDEEAKAKKSLKRLRGSDDITKDITEMRKEREEASNEKKVSIIQLFTNASYRQPILVALMLHAAQQFSGINGIFYYSTSIFQTAGISQPVYATIGVGAVNTVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLSKFPWMNYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTGNFIIALCFQYIADFCGPYVFFLLLVWSWPLFCSHFLKFQKPKENPLRKSQQSSERRGVQLKRQKLL
What is the function of this protein?
Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose.  Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell.  May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.  Also able to mediate the transport of dehydroascorbate.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 2, Glucose transporter type 2, liver, GLUT-2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPT16_MACFA
Sequence: MDAGSSRSLENAVNKIYHDQLVPKINTSKKMSTLAHPPNILEMPQEIKKNCGGKQVEITLERIKMTKSIKEKQSNDLEKAAFKRKAEGEEKPTRKKEAKIIELDNQLITMPLPHIPLKNIMDVEMKLVYIDEVGVRYEFVESFMSTGSQPTCRVAEIVDPLSVPNFSFLPQIDKWLQVALKDASSCYRQKKYALAAGQFRTALELCSKGAVLEEPFDASAEDIASVASFIETKLVTCYLRMRKPDLALNHAHRSIVLNPAYFRNHLRQATVFRCLERYSEAARSAMIADYMFWLGGGREQSISKLIKLYWQAMIEEAITRAESFSVMYTPFATKIRADKIEKVKDVFTKTHPAYAEYIYTDLQTLHMLPQTVDWSSFPPQQYLLTLGFKNKEDGKFLEKISSRKLPIFTEHKTPFGLTREDTVRQMETMGKRILPILDFIRSTQLNGSFPASSGVMEKLQYAGLLSQLQRVKEQSQVINQAMAELATIPYLRDISQQEAELLQSLMADAMDTLEGRRNDNERVWNTIQKVGQIEDFLYQLEDSFLKTKKLRTARRQKTKMKRLQIVQQS
What is the function of this protein?
Essential for spermiogenesis and male fertility (By similarity).  Involved in the formation of sperm acrosome during spermatogenesis (By similarity).
What are the official names of this protein?
Spermatogenesis-associated protein 16.
What is the protein family that this protein belongs to?
Belongs to the SPATA16 family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Shift from Golgi to sperm acrosome.