PharMolix/UniProtQA huggingface dataset:
Protein: PNPH_PLAF7
Sequence: MDNLLRHLKISKEQITPVVLVVGDPGRVDKIKVVCDSYVDLAYNREYKSVECHYKGQKFLCVSHGVGSAGCAVCFEELCQNGAKVIIRAGSCGSLQPDLIKRGDICICNAAVREDRVSHLLIHGDFPAVGDFDVYDTLNKCAQELNVPVFNGISVSSDMYYPNKIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGGILIVDGCPFKWDEGDFDNNLVPHQLENMIKIALGACAKLATKYA
What is the function of this protein?
As part of the purine salvage pathway, catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (PubMed:18957439, PubMed:14982926, PubMed:16131758, PubMed:19575810, PubMed:24416224, PubMed:29440412).  Preferentially acts on inosine and guanosine, and to a lesser extent on 2'-deoxyguanosine and guanosine (PubMed:14982926, PubMed:16131758, PubMed:19575810).  Also catalyzes the phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine; MTI is produced by adenosine deaminase (ADA)-mediated breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis (PubMed:18957439, PubMed:14982926, PubMed:24416224).  Generates hypoxanthine from both the purine salvage pathway and from polyamine metabolism which is required for nucleic acids synthesis (PubMed:18957439, PubMed:14982926, PubMed:24416224).  Has no activity towards adenosine (By similarity).
What are the official names of this protein?
Purine nucleoside phosphorylase, PfPNP, S-methyl-5'-thioinosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family.
Protein: HTPX_PSEFS
Sequence: MMRILLFLATNLAVVLIASITLSLFGFNGFMAANGVDLNLNQLLVFCAVFGFAGSLFSLFISKWMAKMSTSTQVITQPRTRHEQWLLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNKNDALVAVSQGMLERFSYDEVKAVLAHEIGHVANGDMVTLALVQGVVNTFVMFFARIIGNFVDKVIFKNEGGRGIAYFVATIFAEVVLGFLASAITMWFSRKREFRADEAGARLAGTGAMIAALQHLRSEQGLPVHMPDSLTAFGINGGIKQGMARLFMSHPPLEERIDALRRRG
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ESXB_MYCTO
Sequence: MAEMKTDAATLAQEAGNFERISGDLKTQIDQVESTAGSLQGQWRGAAGTAAQAAVVRFQEAANKQKQELDEISTNIRQAGVQYSRADEEQQQALSSQMGF
What is the function of this protein?
A secreted protein.  Acts as a strong host T-cell antigen.  Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm.  Might serve as a chaperone to prevent uncontrolled membrane lysis by its partner EsxA.
What are the official names of this protein?
ESAT-6-like protein EsxB, 10 kDa culture filtrate antigen CFP-10, Secreted antigenic protein MTSA-10.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-1 / type VII secretion system (T7SS).
Protein: YES_RAT
Sequence: MGCIKSKENKSPAIKYTPENPTEPVNTSAGHYGVEHATAATTSSTKGASANFNSLSMTPFGGSSGVTPFGGASSSFSVVPSSYPTSLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGILLDFLKEGDGKYLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGENL
What is the function of this protein?
Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.  Stimulation by receptor tyrosine kinases (RTKs) including EGFR, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates.  Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly.  Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts.  Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration.  Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration.  Plays a role in cell cycle progression by phosphorylating the cyclin dependent kinase 4/CDK4 thus regulating the G1 phase.  Also involved in G2/M progression and cytokinesis (By similarity).  Catalyzes phosphorylation of organic cation transporter OCT2 which induces its transport activity (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase Yes, p61-Yes.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Note=Newly synthesized protein initially accumulates in the Golgi region and traffics to the plasma membrane through the exocytic pathway.
Protein: PB1F2_I02A3
Sequence: MEQEQDTPWTRSIEHINTQRRGNGQQTPKLEHPNSIQLMDHYPRITSRADMHKQIVCWKQWLSSKNPTQGSLKTHVLKRWKLFSKQEWTN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: SPEM2_MOUSE
Sequence: MENQLWQNTLRCCEQYQESPQDAENILFLLLGLIILVNISINVATAMWQGLQNAIDKMIFWMNQKTEVVQVTECPPKEPQPANVQDVHIHCILDPVQVKMAQPTQCSSSSSHYFCKRSNDRRSRRRYGYQQGNLQIHQSSQQQGCLSHQQRLRNRPLSRGYPPFRKQPQGHKMSQMRPMPFFDMEDRDSLPEGHSCPHAKQPRRGWGSLCKPVRLASNVGLWGRQGGILASLPLPSLYLSPELRRLPKRVEAKSELRLQGFGPHYSQSRIWGTVEAEQWASSPPPPRRLLPNPSWVTVGYSSFPSGGHIPYDARDQWRRGTEGCEPPPAFVPRNPREVQGYRDHNSQAHRQNFSSHTHSQPNHSPPQSMGHVGYSSRESHEVRRRAPDWIEVFPSRHPLTTSTSLTALGEASYQRAPPASSGLMIPHSSQRLAEVQISDPTPPPTTFVPLSRNPGGNATYQVYDSLELKRQVQENRGRASSLPPPSTSASRPSLHRSRTGKLN
What are the official names of this protein?
Uncharacterized protein SPEM2.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SEPF_BACC0
Sequence: MSWSKVKYFFFDTPEEKEAAQYSYEKEQTDMKKQQDPPEQQDVTFPKAQPKQNVVSIETAKQSSKVVLLEPRTYSEAQGIADHLKGRRAVVINLQRMSTDQAVRIVDFLSGTVYAIGGDIQKIGPKTFMCTPENVDIVGAISELFGEEEDTNIKRW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: BPIB4_HUMAN
Sequence: MWMAWCVAALSVVAVCGTSHETNTVLRVTKDVLSNAISGMLQQSDALHSALREVPLGVGDIPYNDFHVRGPPPVYTNGKKLDGIYQYGHIETNDNTAQLGGKYRYGEILESEGSIRDLRNSGYRSAENAYGGHRGLGRYRAAPVGRLHRRELQPGEIPPGVATGAVGPGGLLGTGGMLAADGILAGQGGLLGGGGLLGDGGLLGGGGVLGVLGEGGILSTVQGITGLRIVELTLPRVSVRLLPGVGVYLSLYTRVAINGKSLIGFLDIAVEVNITAKVRLTMDRTGYPRLVIERCDTLLGGIKVKLLRGLLPNLVDNLVNRVLADVLPDLLCPIVDVVLGLVNDQLGLVDSLIPLGILGSVQYTFSSLPLVTGEFLELDLNTLVGEAGGGLIDYPLGWPAVSPKPMPELPPMGDNTKSQLAMSANFLGSVLTLLQKQHALDLDITNGMFEELPPLTTATLGALIPKVFQQYPESCPLIIRIQVLNPPSVMLQKDKALVKVLATAEVMVSQPKDLETTICLIDVDTEFLASFSTEGDKLMIDAKLEKTSLNLRTSNVGNFDIGLMEVLVEKIFDLAFMPAMNAVLGSGVPLPKILNIDFSNADIDVLEDLLVLSA
What is the function of this protein?
May have the capacity to recognize and bind specific classes of odorants.  May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites.  May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received (By similarity).
What are the official names of this protein?
BPI fold-containing family B member 4, Ligand-binding protein RY2G5, Long palate, lung and nasal epithelium carcinoma-associated protein 4.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: ITP_SCHGR
Sequence: MHHQKQQQQQKQQGEAPCRHLQWRLSGVVLCVLVVASLVSTAASSPLDPHHLAKRSFFDIQCKGVYDKSIFARLDRICEDCYNLFREPQLHSLCRSDCFKSPYFKGCLQALLLIDEEEKFNQMVEILGKK
What is the function of this protein?
Stimulates salt and water reabsorption and inhibits acid secretion in the ileum of S. gregaria.
What are the official names of this protein?
Ion transport peptide, ITP.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR10_NEOYE
Sequence: MTITQQTKIRIKLKAYNSIILNTSCDKILDTASRTNAVAVGPIPLPTKRRIYCVLRSPHVDKDSREHFEIRSHRRIIDIHQPSSQTIDALMKLNLPSGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AGL61_ARATH
Sequence: MYVTKYKNKLPTLQVDLIIMPHQTQACIYKQTLSLHQIFQQRKATKTLHTKKTMMSKKKESIGRQKIPMVKIKKESHRQVTFSKRRAGLFKKASELCTLCGAEIGIIVFSPAKKPFSFGHPSVESVLDRYVSRNNMSLAQSQQLQGSPAASCELNMQLTHILSEVEEEKKKGQAMEEMRKESVRRSMINWWEKPVEEMNMVQLQEMKYALEELRKTVVTNMASFNEAKDDVFGFLDNKVTVPPYVNMPSGPSNIYNFANGNGCF
What is the function of this protein?
Probable transcription factor.  Controls central cell differentiation during female gametophyte development.
What are the official names of this protein?
Agamous-like MADS-box protein AGL61, Protein DIANA.
What are the subcellular locations of this protein?
Nucleus. Note=The transport to the nucleus is dependent on dimerization with AGL80.
Protein: UVRC_SYNSC
Sequence: MDAASGAPLLTQPERLERRLKEIPAEPGCYLMRDCDDRILYVGKSKALRSRVRSYFRSRHDLSPRIRLMTRQVCEIEFIVTDSEAEALVLESNLIKNHQPHFNVLLKDDKKYPYLCITWSEAYPRIFITRRRRFRSPLDRFYGPYVDVGLLRRTLFLVKRVFPLRQRPRPMYPDRTCLNYSIGRCPGVCQEKISSVDYHRTLRKVAMVFQGRSDELQHLLQEQMERYAERMDYESAARVRDQLQGLDQLTADQKMSLPDSSVSRDVLALAFDERLAAVQLFQMRAGKLVGRLGYTADASGLEPGLILQRVIEEHYSQVDSVEVPPELLVQHALPQQKLMEDWLTEQRERRVQIHCPQRQQKADLIELVQRNAEFELLRAKQGQEKQSLATEDLAQLLELPTPPRRIEGYDISHIQGSDAVASQVVFIDGLPAKQHYRKYKIRSSSIRAGHSDDFMAMAEIMRRRFRRWARAKAEGMDVGALRHKGGSALQTDGLNDWPDVVMIDGGKGQLSAVMEALRELDLHEDLNVCSLAKQREEVFLPGESQPLESEPDQLGVVLLRRLRDEAHRFAVSFHRQQRGERMKRSRLSDIPGVGPKRVKDLLAHFHSIDAIQLASIETLSKAPGVGPALARDIHDFFHPSDEGTDADARAALEEQPQELSA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALKD_PSEAE
Sequence: MHNLEQKTARIDTLCREARILPVITIDREADILPMADALAAGGLTALEITLRTAHGLTAIRRLSEERPHLRIGAGTVLDPRTFAAAEKAGASFVVTPGCTDELLRFALDSEVPLLPGVASASEIMLAYRHGYRRFKLFPAEVSGGPAALKAFSGPFPDIRFCPTGGVSLNNLADYLAVPNVMCVGGTWMLPKAVVDRGDWAQVERLSREALERFAEHRRH
What are the official names of this protein?
2-dehydro-3-deoxy-phosphogluconate aldolase, KDPG-aldolase, Phospho-2-dehydro-3-deoxygluconate aldolase, Phospho-2-keto-3-deoxygluconate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KHG/KDPG aldolase family.
Protein: LEUC_METFK
Sequence: MSAKTLYDKLFDSHVVREENGAALIYIDRHLVHEVTSPQAFEGLKMAGRKLWRVNSVLAVPDHNVPTTDRSHGIADPISRLQVETLDQNCRDFGVTEFRMGDVRQGIVHVMGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVMATQCLVQKKSKAMQIRVEGQLGPGVTAKDVALAIIGKIGTAGGTGYAIEFAGSAIRSLSMEGRMTLCNMAIEAGARAGMVAVDDVTINYVKGRPYAPKPEQWDAAVAYWRTLHSDEGAKFDAVVEIKAEDIEPQVTWGTSPEMVTAINSIVPDPSKESDPTKRSGMERALQYMGLQPNTPISDIPIDKVFIGSCTNSRIEDLRAAAAVAKGKHVAPNVKLAMVVPGSGLVKAQAEQEGLDKIFKEAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGAGGRTHLVSPGMAAAAAVAGHFIDVRQLLN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SYP_METBF
Sequence: MAESEKEAALPPKEEFSEWYNELLWMAEIMDVRYPVKGLYVWYPFGFAIRRNTYNIIREILDNSGHQEALFPLLIPENEFMKEAEHIKGFEDEVYWVTHGGRDTLDIPLALRPTSETAIYPMYKMWVRSHADFPIKIYQIVNTFRYETKHTRPLIRLREITSFKEAHTVHATWEDAEAQVKEAIGLYTEIYRRLGVPVLRSRRPDWDKFPGADYTDALDAIMPDGRTLQIGTAHHLGDNFAKTFDIKYETPDGEQRYAYQTCYGISERSIAATISIHGDDKGLVLPPEIAPVQVVIIPIIFKKGAEEVLAACKDVKERLTKAGIRVEIDASDLRPGAKYYKWEMKGVPLRLEIGPRDLQNNVAVAVRRDTGEKEQISLPEIEAGVSSKFEAIHENLYQKAKVELENRIFECTELEEVKNKIQDGVATIPWCGKRECGRAMEDVIGAGILGIPLEQKRDRKEKCPICGEETETRVYVARTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_BURMS
Sequence: MSTMTPAEIVSELDKHIIGQAKAKKAVAVALRNRWRRQQVAEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFIKIEATKFTEVGYVGRDVDSIVRDLIEISVKQTRETEMRKVRSKATDLAEDRILDVLLPQPRAVGFGASAEHANDDNNATRQTFRKRLREGQLDDKEIELDIEQPAVGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIREALKLLTDEEAAKMLNDEEVKTKAVQNVEQNGIVFLDEIDKITSRNHEGGGGEVSRQGVQRDLLPLVEGTTINTKYGMVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELDSLSVKDFEAILVATDASLVKQYQALLATEDVKLEFADDGIRRLAEIAYAVNEKTENIGARRLYTVIEKLLEEVSFAAGNHAGQSVTIDSAYVDRALGEVSKDEDLSRYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTPB2_MOUSE
Sequence: MDSRVSELFGGCCRPGGGPAMGGNLKARGAGGSSSCGGPKGKKKNGRNRGGKANNPPYLPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEEEMRASLKTLHRMAEKVGADITVLREREVDYDSDVPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIAGTTREHLGLALALKVPFFIVVSKVDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQAATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRRGFQVTVHVGNVRQTAVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGHVTDVQAITAGEAQATMGF
What are the official names of this protein?
GTP-binding protein 2, GTP-binding-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. GTPBP1 subfamily.
Protein: RLMH_HAEI8
Sequence: MKITLIAVGTKMPSWVTTGFEEYQRRFPKDMPFELIEIPAGKRGKNADIKRILEQEGKAMLAACGKGKVVTLDIPGKPWTTPQLAEQLEAWKNDGCDVCLLIGGPEGLSPECKAAAEQSWSLSPLTLPHPLVRVVVAESLYRAWSLTTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_CHAVU
Sequence: MNLISKKNELKQGFYPLFFLEEFYTRVLIHMNHNHILKIGNIKESKLIHVNRICHYLLIKRLIRQIRKQSHKYNGISEFPNYETEFYFQYKNRFYNLIIENAFLLILQMIWQHQKTRKNDPSILIHRSIQSAFPFLEKKIIHCIWIIHGKIQLFHTIEQFNFLFLLLYERIRDKSFLHLLKNILNLNKEFLIEKFYCEKFHLIELSMFFRNLYINEFDSFIVYHIVKTWKLAYLLNPIKAIDDFSFIQKNDILLNIKRKQKRLPLVCWLANKSFYSLYGNIHYVRRDLSFLMAIQAGKHISRFWKYNCIKFLQLKLGFPCSLDVLYLKSLFNQDFLFLGYRIVNKLWKKNFKIRAVSWYSPILFFLKGRRISTKMPVFNLIDRLSVMHLCNLEGYPIHKAAWSVFNDKQIMNIFSNLLRNILFYYSGCSNRSDLGKIQYILEFSCMKTLAFKHKSSIRSTWTQYKKHVSFLSLVKNRHKNGKTSVDLYFLFQKTNKFWLLDLSKIQDSLACFILMD
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPO10_HYPBU
Sequence: MIIPMRCFTCGRPLAQYWEEFRSRVEGGEDPRKVLDELGVKRYCCRKTLLAHVPAIYEVRKFKRVL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_RHOPA
Sequence: MIIAIDGPAASGKGTLAKRLAAHYGFRYLDTGVIYRAVAKAMLDAGADLTDEARAAEVARTLDPSRFDDPALKSHAVGEAASVVSAHPQVRAALVEFQKTFAAAPPGAVLDGRDIGTVICPDAEVKIFVVASPEVRAHRRFLEAQSRGEPADEAVILSDIVKRDERDKNRSAAPLKQAPDAVLLDNSYLDIEGGVRAAIDIVEAVRAGRRRV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEDF_ASPTN
Sequence: MPKLVLLSSATLDEQLSRATPALIRWILLRSASHVYRDLVETEAFLRAQGDWVSTVFIKPGGLSLDVQRGHALSLTEEKSPLSYADLAAAMIEAATDPDGRWDMRNVGVISVNGPAKSPPGAPMCIFMGFVRHYFPFLHPYLPSTGPG
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of geodin, an intermediate in the biosynthesis of other natural products (PubMed:7665560, PubMed:19549600, PubMed:24009710).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) gedC (PubMed:12536215, PubMed:19549600).  The atrochrysone carboxyl ACP thioesterase gedB then breaks the thioester bond and releases the atrochrysone carboxylic acid from gedC (PubMed:19549600).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodinanthrone (PubMed:24009710).  The next step is performed by the emodinanthrone oxygenase gedH that catalyzes the oxidation of emodinanthrone to emodin (PubMed:1810248).  Emodin O-methyltransferase encoded probably by gedA then catalyzes methylation of the 8-hydroxy group of emodin to form questin (PubMed:1444712).  Ring cleavage of questin by questin oxidase gedK leads to desmethylsulochrin via several intermediates including questin epoxide (PubMed:3182756).  Another methylation step probably catalyzed by methyltransferase gedG leads to the formation of sulochrin which is further converted to dihydrogeodin by the sulochrin halogenase gedL (PubMed:24009710).  Finally, the dihydrogeodin oxidase gedJ catalyzes the stereospecific phenol oxidative coupling reaction converting dihydrogeodin to geodin (PubMed:7665560).
What are the official names of this protein?
Oxidoreductase gedF, Geodin synthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the avfA family.
Protein: AAC6_ACIG1
Sequence: MNIMPVSESLMADWLGLRKLLWPDHDEAHLQEMQRLLQQTQSLQLLAYSDTQQAIAMLEASIRYEYVNGTQTSPVAFLEGIYVLPDYRRSGIATHLVQQVEAWAKPFGCIEFASDAALDNRISHAMHQALGFHETERVVYFKKHIG
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring including amikacin, kanamycin, tobramycin and netilmicin.
What are the official names of this protein?
Aminoglycoside N(6')-acetyltransferase type 1, AAC(6')-Ij, Aminoglycoside resistance protein.
Protein: RL24_MYCS2
Sequence: MKVHKGDTVLVISGKDKGAKGKVLVAYPDRNKVLVEGVNRIKKHTAVSANERGASSGGIVTQEAPIHVSNVMVVDSDGKPTRVGYRIDDETGKKVRIAKTNGKDI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL10_ECO81
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PANC_ECO24
Sequence: MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAGERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLIDNKMVELA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.