PharMolix/UniProtQA huggingface dataset:
Protein: ENO_ECOHS
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SYC_LACLM
Sequence: MKIYNTYSRQLEDFQPIEPGKVKMYVCGPTVYNYIHVGNARSVVAFDLVRKYLEFRGFEVEYISNFTDVDDKIIKAAASENISTKELSERYIAAFYEDTDLLNVKRASQNPKATEFIEAMIDFIQELLDKDYAYISEGDVYFRVAKSKDYAKLANKNLADLLAGASGRTDEETNLKESPADFALWKSVKADEVSWQAPWGAGRPGWHIECSVMSTSLLGETIDIHGGGADLEFPHHTNEIAQSEAKTGQKFVNYWMHNGFVNVDGEKMSKSLGNFTTVHELLQVVDPQILRFFLTTTHYRRPLNFTDDALTEAENNIKKIENAYRHLDDQAESNLSALTTFRNDFVAAMDEDFNIANGMTVFYDFVSWVNKGNGGAEVKAFFDQVLEILGIKFEIEQSLDSEIEAMIEERQLAREVRDFAKSDEIRDALKAQGIVLEDTKDGVRWHRE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIM2_BPPH1
Sequence: MTIKNRGPYTLIKAAVQRLIKKYKTSNPYELASYININVIPWNLHHEIMGFYKYDKRNKYIVINSNLNQAERTFVCSHELGHAQLHPRANTPFMKERTLFSVDKYEVEANTFAVELLLPDWVVSQYKNTEFTLDDIAVMNGVPAELAHLKDLSELKNF
What are the official names of this protein?
Uncharacterized immunity region protein 2.
Protein: CA12_CONLT
Sequence: MGMRMMFIMFMLVVLATTVDTFTSDRALDAMNAAASNKASRLIALAVRGCCARAACAGIHQELCGGRR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).  Has a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (Ala-Xaa-Ala instead of the conserved Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Lt1.2, Lt1b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPD_ALTMD
Sequence: MTSPRVVAVIPAAGVGSRMQADRPKQYLSLNGKTILEHTIDALLNHPLIDDVIVAISQGDEYFDQLGLRQKPIRVVDGGKERADSVLNGILSLDENDWALVHDAARPCVDDADISNLLSLIGSEDVTGGILATPVRDTMKRVKPSSNIISHTEDRNGLWHALTPQLFPAMLLKRALQEGLAQGVSITDEASAMEFAGHSVAMVSGSPANIKITHPADLPLAEFYLKQKFSAQGDSAKN
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PHI1_ORYSJ
Sequence: MAASSAAFAACLLACALLFQMCVASRKLTALVQDQPITMTYHKGALLSGRIAVNLIWYGNFSAPQRAVITDFVSSLSTPPSPQPQPEPSVASWFKTAQKYYANSKARFPALSLGQHVLDQSYSLGKRLGEKDLVRLAARGSPSRAINVVLTADDVAVDGFCMSRCGTHGASPRSRAGRFAYVWVGNPATQCPGQCAWPYHQPVYGPQAAPLTPPNGDVGVDGMVISLASMIVGTVTNPFGNGFFQGDADAPLEAATACAGVYGKGAYPGYAGSLLVDPASGASYNANGAHGRKYLVPALVDPDTSACSTVG
What is the function of this protein?
Involved in the control of organ size (PubMed:24486766).  Upon auxin signaling, is targeted by the transcription activator SMOS1 to regulate cell expansion during organ size control (PubMed:24486766).  May promote cell expansion by modulating microtubule organization (PubMed:24486766).
What are the official names of this protein?
Protein PHOSPHATE-INDUCED 1 homolog, OsPHI-1.
What is the protein family that this protein belongs to?
Belongs to the EXORDIUM family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, apoplast.
Protein: HSLO_GEOSM
Sequence: MTDYLVRAIAKSGSVRALVCVTTATVGEICKRHDTLPTATAALGRGITAGALMGSLVKTGQRVALRFEGNGPLKKIVIEADANGSVRGYVGDPKVHLLRPDGALDVNNALGRAGFLTVAKDLGLKEPYRGTVQLYTSGIAEDLALYLVESEQIPSAVGIAEFIEQDGTVAAVGGFLIQAVPPVDPLVVEELMTRIEQLPPLSELLHEGGNPEQILEQLLAGIPYDILEKRNIAFACSCSRERIERVLLSMGKKELSSMKKDQHGSEVTCEFCGERYLFDEADLDRIIAEIAKQES
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNB_INBMD
Sequence: MNNATFNYTNVNPISHIRGSIIITICVSFTVILIVFGHIAKIFTNKKNCTNNVIRVRERIKCSGCEPFCNKRDDISSPRARVDIPSFILPGLNLSESTPN
What is the function of this protein?
Putative viral proton channel.  May play a role in virus entry (By similarity).
What are the official names of this protein?
Glycoprotein NB.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses type B glycoprotein NB family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type III membrane protein.
Protein: YM30_YEAST
Sequence: MVKKHQNSKMGNTNHFGHLKSFVGGNVVALGAGTPYLFSFYAPQLLSKCHIPVSASSKLSFSLTIGSSLMGILAGIVVDRSPKLSCLIGSMCVFIAYLILNLCYKHEWSSTFLISLSLVLIGYGSVSGFYASVKCANTNFPQHRGTAGAFPVSLYGLSGMVFSYLCSKLFGENIEHVFIFLMVACGCMILVGYFSLDIFSNAEGDDASIKEWELQKSRETDDNIVPLYENSNDYIGSPVRSSSPATYETYALSDNFQETSEFFALEDRQLSNRPLLSPSSPHTKYDFEDENTSKNTVGENSAQKSMRLHVFQSLKSSTFIGYYIVLGILQGVGLMYIYSVGFMVQAQVSTPPLNQLPINAEKIQSLQVTLLSLLSFCGRLSSGPISDFLVKKFKAQRLWNIVIASLLVFLASNKISHDFSSIEDPSLRASKSFKNISVCSAIFGYSFGVLFGTFPSIVADRFGTNGYSTLWGVLTTGGVFSVSVFTDILGRDFKANTGDDDGNCKKGVLCYSYTFMVTKYCAAFNLLFVLGIIGYTYYRRRATANSL
What are the official names of this protein?
Uncharacterized membrane protein YMR155W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS3A_HALWD
Sequence: MSERSVSKQKSSDRWYSIIAPEQFDRSELGSTFADDPEKIHGRTLEVTLGDITGDQGENNTKLTFKVNDVTSDAAYTEFIKHELARDYLRSLIRRGASKIDAAITVRTTDDYRVQLQPVAFTTKKADRSQEQAIRRVMIDLVEDAADERTFADLIDAAIEGQLSSAIYGEAKTIYPLRRVEVKKLTLEARPEEVAAEEAAAVDVDEADVAVE
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: URED3_BRASB
Sequence: MRADPASAAADIFEANRARGAVRFDVRLQDGMTRRHHLHESGSLRVRFPSPEDDGLSAMFVNTAGGIAGGDRFAVEVAAGEGSRVTLSSAAAEKVYRAPGKPAELDIALTAAAGAHIAWLPQETILFDRARIHRRIDIDLAATASLLLCEIVVFGRTAMGERMREGEFVDRWRLRRGGRLVFAETVRLDGDIGGKLAHPAIANGAAAIGTALIVPGDAALVERIRESLPAFRGEAGLSAWNGFAMARFCAQDAASLRADMMAVLGCASAVPLPRLWLN
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 3.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTXBC_BACSU
Sequence: MSKENNYHHLAQKILELCGGKSNISSYTHCMTRLRITPYDESKADAQALRKLDGVLGVVEAETLQIILGTGVVNHVTAAFSKLVSAEEGADVKEAAAKKKADINRKNATPFKLFLRKIASIFIPLIPALVASGLITGITKAIIQAGWLSADSQIAIILTVIGSGLFTYLGILVGINASKEFGGTPALGALAGILIINPEIAKISLFGEELLPGRGGLIGVLFAAIFIAYTEQFIRRFIPQSLDIIVTPTVSLLITGIVTYVVFMPLGGFISDAITSGLLSILDIGGIAAGFILGATFLPLVVTGLHQGLTPVHMELINSIGNDPLLPILAMGGAGQVGAAFAVFVKTKKTTLRKAIAGGLPSGLLGIGEPLIFGVTLPLGRPFLTACLGAGIGGAFQAYFQVATIAIGVSGLPLSFLVLPSQIILYIVGLFISYAAGFLLTYAFGYKDEMASQFD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.
What are the official names of this protein?
Putative PTS system EIIBC component YbbF.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUSG_AQUAE
Sequence: MSEQQVQELEKKWYALQVEPGKENEAKENLLKVLELEGLKDLVDEVIVPAEEKVVIRAQGKEKYRLSLKGNARDISVLGKKGVTTFRIENGEVKVVESVEGDTCVNAPPISKPGQKITCKENKTEAKIVLDNKIFPGYILIKAHMNDKLLMAIEKTPHVFRPVMVGGKPVPLKEEEVQNILNQIKRGVKPSKVEFEKGDQVRVIEGPFMNFTGTVEEVHPEKRKLTVMISIFGRMTPVELDFDQVEKI
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: MED4_PHANO
Sequence: MEDVLSTHFDRIEKALSTLVDSIAAYNPSPQAAIDLVAADDQLSHGLDQLSRHQANHARILTLRAQVEALEEQKKSSVTALATLRHELHATPATSFPADTRPVRFDELLQYAKNISQYTVPPTYRERAPEAASDKDRDKDDAASSGVNTPAHAPAQPDSDAPKDRDNADNKPAEVTAEEEEWLEKLQKSQIAWYPWPSEEKIRIGNLSKLMYWQARGKDVDDFDIPAHEEAQRKGLAGVVEAPPEPEPVAEPVQAQAPRPARPAQPQATFDMFDDLDD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 4, Mediator complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNAS1_GIRCA
Sequence: KESAAAKFERQHIDSSTSSVSSSNYCNEMMTSRNLTQDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSAMSITDCRETGNSKYPNCAYQTTQAEKHIIVACEGNPYVPVHYDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: MFD_STAAC
Sequence: MTILTTLIKEDNHFQDLNQVFGQANTLVTGLSPSAKVTMIAEKYAQSNQQLLLITNNLYQADKLETDLLQFIDAEELYKYPVQDIMTEEFSTQSPQLMSERIRTLTALAQGKKGLFIVPLNGLKKWLTPVEMWQNHQMTLRVGEDIDVDQFLNKLVNMGYKRESVVSHIGEFSLRGGIIDIFPLIGEPIRIELFDTEIDSIRDFDVETQRSKDNVEEVDITTASDYIITEEVISHLKEELKTAYENTRPKIDKSVRNDLKETYESFKLFESTYFDHQILRRLVAFMYETPSTIIEYFQKDAIIAVDEFNRIKETEESLTVEPDSFISNIIESGNGFIGQSFIKYDDFETLIEGYPVTYFSLFATTMPIKLNHIIKFSCKPVQQFYGQYDIMRSEFQRYVNQNYHIVVLVETETKVERMQAMLSEMHIPSITKLHRSMSSGQAVIIEGSLSEGFELPDMGLVVITERELFKSKQKKQRKRTKAISNAEKIKSYQDLNVGDYIVHVHHGVGRYLGVETLEVGQTHRDYIKLQYKGTDQLFVPVDQMDQVQKYVASEDKTPKLNKLGGSEWKKTKAKVQQSVEDIAEELIDLYKEREMAEGYQYGEDTAEQTTFELDFPYELTPDQAKSIDEIKDDMQKSRPMDRLLCGDVGYGKTEVAVRAAFKAVMEGKQVAFLVPTTILAQQHYETLIERMQDFPVEIQLMSRFRTPKEIKQTKEGLKTGFVDIVVGTHKLLSKDIQYKDLGLLIVDEEQRFGVRHKERIKTLKHNVDVLTLTATPIPRTLHMSMLGVRDLSVIETPPENRFPVQTYVLEQNMSFIKEALERELSRDGQVFYLYNKVQSIYEKREQLQMLMPDANIAVAHGQMTERDLEETMLSFINNEYDILVTTTIIETGVDVPNANTLIIEDADRFGLSQLYQLRGRVGRSSRIGYAYFLHPANKVLTETAEDRLQAIKEFTELGSGFKIAMRDLNIRGAGNLLGKQQHGFIDTVGFDLYSQMLEEAVNEKRGIKEPESEVPEVEVDLNLDAYLPTEYIANEQAKIEIYKKLRKTETFDQIIDIKDELIDRFNDYPVEVARLLDIVEIKVHALHSGITLIKDKGKIIDIHLSVKATENIDGEVLFKATQPLGRTMKVGVQNNAMTITLTKQNQWLDSLKFLVKCIEESMRISDEA
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRS3_CAVPO
Sequence: MSQKQPQSPNQTLISITNDTESSSSVVSNDTTNKGWTGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLALGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCAKAGCIWIMSMIFALPEAIFSNVHTLRDPNKNMTSEWCAFYPVSEKLLQEIHALLSFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQVESRKRIAKTVLVLVALFALCWLPNHLLNLYHSFTHKAYEDSSAIHFIVTIFSRVLAFSNSCVNPFALYWLSKTFQKQFKAQLFCCKGELPEPPLAATPLNSLAVMGRVSGTENTHISEIGVASFIGRPMKKEENRV
What is the function of this protein?
Role in sperm cell division, maturation, or function.  The relative order of ligand affinity is GRP = neuromedin-C >> neuromedin-B.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Bombesin receptor subtype-3, BRS-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OBG_STAAT
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK2A_ATRBE
Sequence: MAIHLYKTSTPSTRNGTVDSQVKSNPRNNLIYGQRRCGKGRNARGIITARHRGGGHKRLYRKIDFRRNEKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNVGVNQKSLGRAGSKRWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPTTPWGYPALGRRSRKRNKYSDNLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2-A, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACCD_PSE14
Sequence: MSNWLVDKLIPSIMRSEVKKSSVPEGLWHKCPSCEAVLYRPELEKTLDVCPKCNHHMRIGARARLNIFLDVEGREELGADLEPVDRLKFRDGKKYKDRLTAAQKQTGEMDALISMSGTLLGMPVVASAFEFSFMGGSMGAIVGERFVRAANYALENRCPMICFAASGGARMQEALISLMQMAKTSAVLARLREEGLPFISVLTDPVYGGVSASLAMLGDVIVAEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLLDHGAIDMIISRSELRPRLGNLLAQMMNLPTPRFVAPVIEPIVVPPAPATI
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_SYNP2
Sequence: MKIVLQRVQQSHVSVNQHIVGQINQGLTLLVGISPTDTDAELQWLARKCLDLRLFPDPEGNPWQASIQDIQGEILVVSQFTLYGDCRKGRRPSFSGSAKPDQAEQIYEKFVAFLRQSGLKIETGQFGAMMQVEISNDGPVTLLLEREAKPA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACMA_LACLA
Sequence: MPVSRIKVKNRHLKKKAKKPLAFYKPATKFAGAVLIAGTLTTTHELLLQQTSPMVQAATNSTEAFIESIAASAKPVADSNGLYPSVMIAQAILESNWGSSQLSRAPYYNLFGIQGTYQGKSVVFKTQEYLNGKWVTKDMPFRVYPSFNQSFQDNAYVLKTTNFGNGPYYAKAWRANAATYQAATAALTGKYATDPNYGASLNRIISQYNLTRFDGASSAGTSNSGGSTATNTNNNSNTSSTTYTVKSGDTLWGISQKYGISVAQIQSANNLKSTVIYIGQKLVLTTSSSSSNTNSSTSSGNSAGTTTPTTSVTPAKPASQTTIKVKSGDTLWGLSVKYKTTIAQLKSWNHLNSDTIFIGQNLIVSQSAGSSSSSTGSSSASTSSTSNSSAASNTSIHKVVKGDTLWGLSQKSGSPIASIKAWNHLSSDTILIGQYLRIK
What is the function of this protein?
Required for cell separation during growth.
What are the official names of this protein?
Probable N-acetylmuramidase, Autolysin, Lysozyme, Peptidoglycan hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 73 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRAM3_ECOLX
Sequence: MARVILYISNDVYDKVNAIVEQRRQEGARDKDISVSGTASMLLELGLRVYEAQMERKESAFNQTEFNKLLLECVVKTQSSVAKILGIESLSPHVSGNPKFEYANMVEDIREKVSSEMERFFPKNDEE
What is the function of this protein?
Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell.  It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations.  Part of the relaxosome, which facilitates a site- and strand-specific cut in the origin of transfer by TraI, at the nic site.  Probably autoregulates its own expression (By similarity).  Plasmid specificity is conferred by the TraD-TraM pair.
What are the official names of this protein?
Relaxosome protein TraM.
What is the protein family that this protein belongs to?
Belongs to the relaxosome TraM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPW_CITFR
Sequence: MKATFVLHGWWRTS
What is the function of this protein?
This protein is involved in control of the biosynthesis of tryptophan.
What are the official names of this protein?
trp operon leader peptide.
Protein: FENR1_LISW6
Sequence: MPNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIPAITGENLVANLKEQAETFHPTIVCNERVVDVTRLTDGTFQLITHNGSIHFSKTIVIATGSGTFEVNKLEALHVEDFPLAIHYDVKNIEQFRDKVVAVSGGGNSAIDWAQTLEPIAKQVHLIYRGEDFKAHEESVRELKNSRVKIHIHHEIHELFGTNNQLAEISVICNQTQATKTIETEALFINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKLRIIAAGLHEGPIAINSAKKYLEPTAADEAMISTHHESFIG
What are the official names of this protein?
Ferredoxin--NADP reductase 1, FNR 1, Fd-NADP(+) reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: ENGB_MACCJ
Sequence: MNINPNNVEIIISAVKPDQYPDTGLKEVALAGRSNVGKSSFINTMIGRKSMARISSKPGKTQTLNFFNIDEQLVFVDVPGYGYAKVSKTERERWGKMIETYITTRDNLACVIQLVDIRHNPTEDDRLMYDFLKHYEIPTIVIATKEDKIPKGKIQKHLKIIKQDLDMDSSDTLISYTALSKDKNPMIFNAIEKYL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ILVD_DESVM
Sequence: MRSKKMTHGLEKAPHRSLLHALGLTREEIERPLVGVVNAANEVVPGHVHLHTIAEAVKAGVRAAGGTPMEFPAIAVCDGLAMNHEGMHFSLPSREIIADSIEIMATAHPFDALVFIPNCDKSVPGMLMAMLRMDIPSIMVSGGPMLAGGTLAGRTDLISVFEAVGRVQRGDMTMAELDEMTETACPGCGSCAGMFTANTMNCMAETMGLALPGNGTIPAVTAARVRLAKHAGMKVMELLEKNITPRSIVTPRAVANAVAVDMALGGSTNTVLHLPAVFGEAGLDLTLDIFDEVSRKTPNLCKLSPAGHHHIQDLHAAGGIPAVMAELTRKGLVDTSVMTVTGKTLAENLAELNARVLNPDVIRSADAPYSAQGGIAILKGSLAPQGAVVKQSAVAPEMMVREAVARVFDSEGEAHAAIMGGKINKGDAIIIRYEGPRGGPGMREMLSPTAAIAGMGLGADVALITDGRFSGGTRGAAIGHVSPEAADGGNIGLVREGDHILIDIPARRLDLLVDEAELAARRETFVPLEKPVTSPLLRRYARQVTSAATGAMYRK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RUVA_RHIL3
Sequence: MIGKLKGTIDEIGEDYVLVDVHGVCYVAHCSARTLSKLGSTGEACVLFIETYVREDQLKLFGFMTALEREWFNLLQSVQGVGAKVALAVLSTLPPGELANAIALQDRTAVSRAPGVGPKVAMRLVTELKNRAPAFAGEAINIGLKQELGEGVAAAPVADAVSALTNLGYSRDQAANAIAAAMKTAGEGADSAKLIRLGLKELAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PULA_BACSU
Sequence: MVSIRRSFEAYVDDMNIITVLIPAEQKEIMTPPFRLETEITDFPLAVREEYSLEAKYKYVCVSDHPVTFGKIHCVRASSGHKTDLQIGAVIRTAAFDDEFYYDGELGAVYTADHTVFKVWAPAATSAAVKLSHPNKSGRTFQMTRLEKGVYAVTVTGDLHGYEYLFCICNNSEWMETVDQYAKAVTVNGEKGVVLRPDQMKWTAPLKPFSHPVDAVIYETHLRDFSIHENSGMINKGKYLALTETDTQTANGSSSGLAYVKELGVTHVELLPVNDFAGVDEEKPLDAYNWGYNPLHFFAPEGSYASNPHDPQTRKTELKQMINTLHQHGLRVILDVVFNHVYKRENSPFEKTVPGYFFRHDECGMPSNGTGVGNDIASERRMARKFIADCVVYWLEEYNVDGFRFDLLGILDIDTVLYMKEKATKAKPGILLFGEGWDLATPLPHEQKAALANAPRMPGIGFFNDMFRDAVKGNTFHLKATGFALGNGESAQAVMHGIAGSSGWKALAPIVPEPSQSINYVESHDNHTFWDKMSFALPQENDSRKRSRQRLAAAIILLAQGVPFIHSGQEFFRTKQGVENSYQSSDSINQLDWDRRETFKEDVHYIRRLISLRKAHPAFRLRSAADIQRHLECLTLKEHLIAYRLYDLDEVDEWKDIIVIHHASPDSVEWRLPNDIPYRLLCDPSGFQEDPTEIKKTVAVNGIGTVILYLASDLKSFA
What are the official names of this protein?
Pullulanase, Alpha-dextrin endo-1,6-alpha-glucosidase, Pullulan 6-glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: Y2152_NITWN
Sequence: MTAIRLYVDADACPVKDEIYRVAERHGVSVSVVAGGYIRVPDHPLIERIAAGPGMDAADDWIAERAGKTDIVITADIPLASRCVKAGASVIAPNGKPFTEQSIGMTLAVRNLMTDLRASGEMTGGPRSFQPRDRSAFLSALDQAIRRIRRACAARQG
What are the official names of this protein?
UPF0178 protein Nwi_2152.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.