PharMolix/UniProtQA huggingface dataset:
Protein: TBB2_DROER
Sequence: MREIVHIQAGQCGNQIGGKFWEVISDEHCIDATGTYYGDSDLQLERINVYYNEATGAKYVPRAILVDLEPGTMDSVRSGRFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESEGCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSFFVEWIPNNCKTAVCDIPPRGLKMSATFIGNSTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEEGEFDEDEEGGGDE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-2 chain, Beta-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FTHS_STAAE
Sequence: MTHLSDLDIANQSTLQPIKDIAASVGISEDALEPYGHYKAKIDINKITPRENKGKVVLVTAMSPTPAGEGKSTVTVGLADAFHELNKNVMVALREPALGPTFGIKGGATGGGYAQVLPMEDINLHFNGDFHAITTANNALSAFIDNHIHQGNELGIDQRRIEWKRVLDMNDRALRHVNVGLGGPTNGVPREDGFNITVASEIMAILCLSRSIKDLKDKISRITIGYTRDRKPVTVADLKVEGALAMILKDAIKPNLVQSIEGTPALVHGGPFANIAHGCNSILATETARDLADIVVTEAGFGSDLGAEKFMDIKVREAGFDPAAVVVVATIRALKMHGGVAKDNLKEENVEAVKAGIVNLERHVNNIKKFGVEPVVAINAFIHDTDAEVEYVKSWAKENNVRIALTEVWKKGGKGGVDLANEVLEVIDQPNSFKPLYELELPLEQKIEKIVTEIYGGSKVTFSSKAQKQLKQFKENGWDNYPVCMAKTQYSFSDDQTLLGAPSGFEITIRELEAKTGAGFIVALTGAIMTMPGLPKKPAALNMDVTDDGHAIGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RBL_SYNP2
Sequence: MQTKSAGFNAGVQDYRLTYYTPDYTPKDTDLLACFRMTPQPGVPPEECAAAVAAESSTGTWTTVWTDGLTDLDRYKGRCYNVEPVPGEDNQYFCFVAYPLDLFEEGSVTNVLTSLVGNVFGFKALRALRLEDIRFPVALIKTYQGPPHGITVERDLLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSQPFMRWRDRFLFVQEAIEKSQAETNEVKGHYLNVTAGTCEEMLKRAEFAKEIGTPIIMHDFLTGGFTANTTLAKWCRDNGVLLHIHRAMHAVIDRQKNHGIHFRVLAKCLRLSGGDHLHSGTVVGKLEGDRAATLGFVDLMREDYVEEDRSRGVFFTQDYASLPGTMPVASGGIHVWHMPALVEIFGDDSCLQFGGGTLGHPWGNAPGATANRVALEACVQARNEGRSLAREGNDVLREAGKWSPELAAALDLWKEIKFEFDTVDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=In the carboxysome RuBisCO is organized into a paracrystalline array (By similarity). This cyanobacterium makes beta-type carboxysomes (Probable).
Protein: HEM1_VIBCM
Sequence: MSLLAIGINHNTASVELREKVAFGPEKLSLALNQLSTSSHVKGGVILSTCNRTEIYCDVRSASKNKVIEWLSQFHQVSLDELKPSLYVHEEQAAIRHLMRVACGLDSLVLGEPQILGQVKQAYAEARENHAVNPATEKLFQKAFSVAKRVRTETEIGGSAVSVAYAACTLAKHIFESLADATVLLVGAGETIELVAKHLAGHHCKRMIVANRTRERALSLAQQFGADVIALNEIPDYLAQADIVISSTASPLPIIGKGMVESALKARRHQPMLLVDIAVPRDIEPQVGKLNDAYLYSVDDLQSIVDSNIEQRKVEAIQAEAIVSEESATFMSWMRSLQAVDSIRDYRKQANEAREELLNKSLQALAAGGDPEKLLIELSNKLTNKLIHTPTRALQTAAEQGEPAKLAVIRQSLGLDDLN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SYP_CERS4
Sequence: MRLSRYFLPVLKENPSEAQIVSHRYMLRAGMIKQQAAGIYSWLPLGFKVLKRIEQIVHEEQIRAGHIPLLMPTLQPADLWRESGRYDDYGEEMLRITDRHKRDMLYGPTNEEMITDIFRSHVSSYKDLPLTLYHIQWKFRDEIRPRFGVMRGREFLMKDGYNFDLDYESAIHAYNRHMVSYLRTYERMGLQAIPMRAASGPIGGDNTHEFLVLASTGESEVFYDAAITDLKFGDRVVNYDDRAECEAIVKEWTAPYARTDETHDEAVFGQIPEERRRSSRGIEVGQIFYFGTKYSEPMGANVVTADGSRVPVHMGSHGIGVSRLLGAIIEASHDDKGIIWPEGVTPFHAGIVNLKQGDSSTDLACEALYRDLSARGLEPLYDDRDERAGAKFATMDLIGLPWRITVGPRGISAGKVELTNRRTGESEEMSSGAAVDRLAQIYAGI
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDHD_RHOSU
Sequence: MTAQTCCPPTHDDALARARAGESLWRLGALAFGHPVEEFHRALLDGSFHEAVDAAWSALTGRPWPREAPPARFADLEAGYIAAFEHGRGGKRLASLLAGEHKDLLAGQAPPRLHAERRRFYRHFGLRQATADEGRVDEPDHLACLLEFMAVLSHLEAAAIVGGRDPGPVRRAARDFLVRYVEPMLALIAAVLRRPSEPPLDATLVRLTRDLHGFADSRIAELAAQVGPYRSAEARSDSAPDAAAHQNLWG
What is the function of this protein?
May function as a system-specific chaperone protein essential for the assembly of an active dimethyl sulfide dehydrogenase DdhABC.
What are the official names of this protein?
Dimethyl sulfide dehydrogenase assembly chaperone protein.
What is the protein family that this protein belongs to?
Belongs to the type II DMSO reductase enzyme chaperone family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPRF_BOVIN
Sequence: MTPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFVKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPLGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPAASNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVSYYGIQYRPAGAEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVDSDTRIQLSWLLPPQERIVKYELVYWAAEDEGQQHKVTFDPTSSYTVEDLKPDTLYRFQLAARSELGVGVFTPTIEARTAQSTPSAPPQKVTCVSVGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGIGREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVRVSWKLPVPSKQHGQIRGYQVTYVRLENGEPRGAPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMVSTTAMNTALLQWHPPKELPGELLGYRLQYRRADEARPSTIDFGKDDQHFTVTGLHKGATYIFRLTAKNRAGLGEEFEKEITTPEDVPSGFPQNLRVIGLTTSTTELIWDPPVLAERNGRITNYTVVYRDINSQQELQNVTADTHLTLSGLKPDTTYDIKVRARTSKGAGPLSPSIQSRTMPVEQVFAKNFRVEAAMKTSVLLSWEVPDSYKSAVPFRILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPHKPLPASAYIEDGRFTLTMPRVQEPALVRWFYIMVVPIDRMGGSMLAPQWSTPEELELDELLEAIEQGGGERLRRRRQTERLKPYVAAQVDVLPETFTLGDKKNYQGFYNRPLSPDLSYQCFVLASLKEPVDQKRYACSPYSDEIVVQVTPAQQQEEPELLWVTGPVLAVILIVLIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETYGLIQVTLLDTVELATYTVRTFALYKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRAQRNYMVQTEDQYVFIHEALLEAAMCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLANSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTRLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT
What is the function of this protein?
The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase F.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NUOD_HELP2
Sequence: MAQNFTKLNPQFENIIFEHDDNQMILNFGPQHPSSHGQLRLILELEGEKIIKATPEIGYLHRGCEKLGENMTYNEYMPTTDRLDYTSSTSNNYAYAYAVETLLNLEIPRRAQVIRTILLELNRMISHIFFISVHALDVGAMSVFLYAFKTREYGLDLMEDYCGARLTHNAIRIGGVPLDLPPNWLEGLKKFLGEMRECKKLIQGLLDKNRIWRMRLENVGVVTPKMAQSWGMSGIMLRGTGIAYDIRKEEPYELYKELDFDVPVGNYGDSYDRYCLYMLEIDESIRIIEQLIPMYAKTDTPIMAQNPHYISAPKEDIMTQNYALMQHFVLVAQGMRPPVGEVYAPTESPKGELGFFIHSEGEPYPHRLKIRAPSFYHIGALSDILVGQYLADAVTVIGSTNAVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: C2_CAMPS
Sequence: MESVIFSINGEIIQVNKEIITASPYNFFKRIQEHHINDEAIILNGINYHAFESLLDYMRWKKINITVNNVEMILVAAVIIDIPPVVDLCVKTMIHNINSTNCIRMFNFSKRYGIKKLYNASMLEIINNITAVTSDPEFGKLSKDELTTILSHENVNVNHEDVTAMILLKWIHKNPNDVDIINILHPKFMTNTMCNAISLLGLTISKSTKPVTRNGIKHNIVVIKNSDYISTITHYSPRTEYWTIVGNTDRQFYNANVLYNCLYIIGGMINNRHVYSVSRVDLKTKKWKTVTNMSSLKSEVSTCVNDGKLYVIGGLEFSISTGVAEYLKHGTSKWIRLPNLITPRYSGASVFVNDDIYVMGGVYTTYEKYVVLNDVECFTKNRWIKKSPMPRHHSIVYAIEYDGDIYAITGITHETRNYLYKYIVKEDKWIELYMYFNHVGKMFVCSCGDYILIIADAKYEYYPKSNTWILFDMSTRNIEYYDMFTKDETPKCNVTHKSLPSFLSNCEKQFLQ
What are the official names of this protein?
Kelch repeat protein C2.
What is the protein family that this protein belongs to?
Belongs to the poxviruses Kelch family.
Protein: YL767_MIMIV
Sequence: MMSQTFFLISDPDNLDYPIYTVHDKSRILDCFCDISLFKTTTITEIELDNEHPDFKILKLYGNTFMTNRIIKNTKYSLLDVNTVQMLLDYGDPDYEFKSTHYLYVFYMSQNRFDICDYLIASNIKFVGTYTKSCLLNQNTLTNYHLFKYIINNSEFFGCCHYDLMYAAFRYTKFYDLCDHLIKSEYNCNIDYDNFLRQLFNKTDSNGFTINCELDTFQIKKLIDENYFDNEKLFYTVLYDSFELTKYIVEKGFYYDFDSVINSDINLEMLKFFIELGNNLTDDHIMILLSKKYSNDYCKKITFLLDNNYITEKHFTNKIVSDIVWFDLNLLDYLINKLNIIELINLDILMKTSILRENINMIKKCIEYGINVDDYMKFAVDYSICITKKLIELGGNIPDDICIYNPYHSLSIESIDIILENNYDSLENLLLKIINQNKETLYIDEILHIMGKLISTNKPIPDLNKILIKSCYYSDNIYKEIIKLDLNLDNYQQIFVNIMRKEYDNIEQLIFFSTYYNSIELLFVVVLSENIDLFKLLLEINCNDTDYLSWAFVFSGRCFKLMKYIVDNYNVDIYQRQIEVCIMIPKKDYQTKRYLQLMGYEISCIYNTECNNDKLPLVEFMKELSIDSTIRP
What are the official names of this protein?
Putative ankyrin repeat protein L767.
Protein: RBFA_AROAE
Sequence: MPKEFSRSQRVAEQVRRELAELIRLEVKDPRVGFITLTDVEITPDYAHAKVFFTSMKGEEGLDEILTGLHRASGFLRRELGKRVRIHTLPELHFHYDSSVERGSRMSQLIDQVVRDDDARHKDDPES
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBX11_MOUSE
Sequence: MSSPLASLSKTRKVPLESESVNPGRRGIRVYGNEDEVDMWNDGQDSEEKISLPSCYGGIGAPVSRQGPHDSELMASMTRKLQELEQQLQAQNDEMLSKERKILDLEDLVQTLQQHQNNAALQRQEELETQCIQLQRQIGEMERFLSDYGLQWVGEPMDQENSEEKTVSENDERDWMKAKKFWKPGDSFVPPEVDFDKLMASLQDLSELVEGEAQVTPVPGGARFRTLEPIPLKVYRNGIMMFDGPFRPFYDPSTQRCLRDILDGFFPSELQRLYPDGVPFKVSDLRNQIYPEDGLGQFPGEGRVVGRQKMRKVTDRVEETSGSRMTAEQFLNRLPKCIIRQGEVIDIRGPIRDTLQNCCPMPARIQEIIVETPALASERQRSQESPDMPMPLLSMLRIKSENGEQAFLLMMWPEDTIGDVRKLLAQARDMDSAAFEILSTFPPTVYQDDTVTLQAAGLVPNATLLLRTRRALLSNPISRPGSLP
What is the function of this protein?
May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 and RND3.  Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity).
What are the official names of this protein?
UBX domain-containing protein 11, Socius, UBX domain-containing protein 5.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PIGV_MOUSE
Sequence: MGLLDPSQKEVLRFAVNCRILTLVLQALFNLIIPDHHADAFCPPRLAPSGSADQLVEGLLGGLSRWDAEHFLFIAEHGYLYEHNFAFFPGFPLALLMGTELLRPLQGLLSQRSCLLVSVALLNLLFSVLAAVALHDLGCLVLHCPRQALCAALLFCISPANVFLAAGYSEALFAFLTFSAMGQLERGRGWASGLLFALAAGVRSNGLVSLGFLLHSQCRGFCSSLAVLSPWKPLVKLMASVCLSVLIVSLPFALFQYRAYIQFCSPGSAPSIPEPLLQLAADKGYRLAGENAPPWCSWDLPLIYNYIQDVYWNVGLLRYYELKQVPNFLLATPVTVLVVWATWTYVTTHPWLCLTLGLQRTKDRENPEKPHRGFLSPKVFVYLVHAAALLVFGGLCMHVQVLTRFLASSTPIMYWFPAHLLQDQEPLLRCVDTEPGKLPQEKSPPGQKAPRNCLMKLFYDWKRCSPVTRCVLVYFLTYWLLGLILHCNFLPWT
What is the function of this protein?
Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 2, GPI mannosyltransferase II, GPI-MT-II, Phosphatidylinositol-glycan biosynthesis class V protein, PIG-V.
What is the protein family that this protein belongs to?
Belongs to the PIGV family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HEK2_YEAS8
Sequence: MSQFFEAATPVAIPTNNTNGGSSDAGSAATGGAPVVGTTAQPTINHRLLLSLKEAAKIIGTKGSTISRIRAANSVKIGISEKVPGCSDRILSCAGNVINVANAIGDIVDVLNKRNPENEDAAEGEAEEHYYFHFLNHILPAPSKDEIRDLQQLEDIGYVRLIVANSHISSIIGKAGATIKSLINKHGVKIVASKDFLPASDERIIEIQGFPGSITNVLIEISEIILSDVDVRFSTERSYFPHLKKSSGEPTSPSTSSNTRIELKIPELYVGAIIGRGMNRIKNLKTFTKTNIVVERKDDDDKDENFRKFIITSKFPKNVKLAESMLLKNLNTEIEKRENYKRKLEAAEGDATVVTERSDSASFLEEKEEPQKNHDNKEEQS
What is the function of this protein?
RNA-binding protein involved in the correct localization of transcripts in the cell.  RNA localization is a widespread mechanism for achieving localized protein synthesis.  Required for the asymmetric localization to the daughter cell nucleus of the ASH1 transcript, coding for a specific repressor of transcription.  Overexpression inhibits translation of the ASH1 transcript.  Involved in the stability of transcripts, like the MTL1 mRNA.  Involved in structural and functional organization of telomeric chromatin and regulates silencing at the HMR locus (By similarity).
What are the official names of this protein?
Heterogeneous nuclear rnp K-like protein 2, KH domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the HEK2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Nucleus. Chromosome, telomere.
Protein: GCST_YERPG
Sequence: MAKQTPLYDQHVACGARMVDFHGWMMPLHYGSQIDEHHFVRQDAGMFDVSHMTIVDLHGNRTREFLRYLLANDVAKLTQPGKALYTGMLNESGGVIDDLIVYFLSEDYFRLVVNSATRDKDLAWISQHAEPYQVEVTVRDDLALIAVQGPQAQQKVATLLTTEQQQAIAGMKPFFGIQTGDLFIATTGYTGEAGYEIALPKQQVVAFWQQLLAAGVKPAGLGARDTLRLEAGMNLYGQEMDEKTSPLAANMGWTVAWQPEDRQFIGRAALERQRMKGTEQLVGLIMTEKGVLRNELPVYFFDAAGNQHVGVITSGSFSPTLGFSIALARVPAGIGEHAVVQIRNREMPVRVTKPGFVRAGKAIVL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: BPHS4_PICSI
Sequence: MAIVSSVPLASKSCLHKSLISSIHKLKPFCRTIPTLGMSRPGKSVMPSMSMSSPVSDDGVQRRTGGYHSNLWNDDIIQFLSTPYGEPAYRERGERLIDEVKNMFNSISMEDVEFSPLNDLIQRLWIVDSVERLGIDRHFKNEIKSTLDYVYSYWTQKGIGCGIESVVPDLNSTALGLRTLRLHGYPVSAEVLKHFQNQNGQFACSPSETEGEMRSIVNLYRASLIAFPGEKVMEEAEIFSTKYLKEALQKIPVSSLSREIGDVLEQDWHTNLPRLEARNYIDVFGQDTKDTKLYMKTEKLLELAKLEFNIFQSLQKTELDSLLRWWKDSGFHHITFSRHLHVEYYTLASCIAFEPQHSRFRLGFAKACHVITILDDMYDVFGTIDELELFTAQIKRWDPSATDCLPKYMKRMYMILYDMVNEMSREAETAQGRDTLNYARQAWEDFIDSYMQEAKWIATGYLPTFDEYFENGKVSSGHRVAALQPILTMDIPFPHDILKEVDFPSKLNDLASAILRLRGDTRCYKADRARGEEASCISCYMKDNPGATEEDALSHINAVINDVIKGLNWELLNPNSSVPISSKKHVFDVSRALHYGYKYRDGYSVSNIETKSLVMRTLLESVPF
What is the function of this protein?
Terpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens (PubMed:21385377).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to (-)-beta-phellandrene (PubMed:21385377).
What are the official names of this protein?
(-)-beta-phellandrene synthase 4, chloroplastic, Terpene synthase TPS-Phel-4, PsTPS-Phel-4.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2026_MYCBO
Sequence: MVKRSRATRLSPSIWSGWESPQCRSIRARLLLPRGRSRPPNADCCWNQLAVTPDTRMPASSAAGRDAAAYDAWYDSPTGRPILATEVAALRPLIEVFAQPRLEIGVGTGRFADLLGVRFGLDPSRDALMFARRRGVLVANAVGEAVPFVSRHFGAVLMAFTLCFVTDPAAIFRETRRLLADGGGLVIGFLPRGTPWADLYALRAARGQPGYRDARFYTAAELEQLLADSGFRVIARRCTLHQPPGLARYDIEAAHDGIQAGAGFVAISAVDQAHEPKDDHPLESE
What are the official names of this protein?
Uncharacterized protein Mb2026c.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0638, MJ1123 and MJ1252.
Protein: KBP_ECOLI
Sequence: MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLNKTGIPDADKVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGIASVDDQVKTATPATASQFYTVKSGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE
What is the function of this protein?
Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+).  May act as a sensor of cytoplasmic K(+) concentration.  Binds a single K(+) ion, which induces a large conformational change.  Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+) (PubMed:27112601).  May be involved in the regulation of peptidoglycan cross-linking (PubMed:25422305).
What are the official names of this protein?
Potassium binding protein Kbp, K(+) binding protein Kbp.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_SODGM
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERYGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVVEGGMTNLERRQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKNMDLEQECEQLREELEETNSETKRKKLTKRIKLLEAFVLSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDRVNGKGEGMVLTGPKEAERIYRAGVAELHARVKVRITEHEKRDNGESVENTHLVDTTVGRAILWMIVPKGLPFSLVNQALGKKAISKMLNTCYRVLGLKPTVIFADQIMYTGFAYAARSGSSVGIDDMVIPAKKAEIIDEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMDNLSTEAVINRDGEEERQVSFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTFAGIVMTPVIEGGDVKEPLRERVLGRVTAEDVLKPGTADILVERNTLLNEKWCDVLEENSVDSVKVRSVVTCDTDFGVCANCYGRDLARGHLVNKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGTIRLSNAKFVVNGSGKLVITSRNTELKLVDEFGRTKESYKVPYGAVMAKGDGAEIMGGETVANWDPHTMPVITEVDGFVRFTDMIDGQTITRQTDELTGLSSIVILDTAERTSGGKDLRPALRIVDANGNDVLLPGTDMPAQYFLPGKTIVQLEDGAKITGGDTLARLPQETSGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVISPVDGSDAYEEMIPKWRQLNVFEGERVERGDVISDGPESPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIASSGSSEFLEGEQVEYSRIKIANRQLENDGKVEMTYVRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQERARHRQQGEAPAAPQITADEASANLAELLNAGLGGNDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PPIA_MOUSE
Sequence: MVNPTVFFDITADDEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSSFHRIIPGFMCQGGDFTRHNGTGGRSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITISDCGQL
What is the function of this protein?
Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:24429998).  Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (By similarity).  Activates endothelial cells (ECs) in a pro-inflammatory manner by stimulating activation of NF-kappa-B and ERK, JNK and p38 MAP-kinases and by inducing expression of adhesion molecules including SELE and VCAM1 (By similarity).  Induces apoptosis in ECs by promoting the FOXO1-dependent expression of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity).  In response to oxidative stress, initiates proapoptotic and antiapoptotic signaling in ECs via activation of NF-kappa-B and AKT1 and up-regulation of antiapoptotic protein BCL2 (By similarity).  Negatively regulates MAP3K5/ASK1 kinase activity, autophosphorylation and oxidative stress-induced apoptosis mediated by MAP3K5/ASK1 (By similarity).  Necessary for the assembly of TARDBP in heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and regulates TARDBP binding to RNA UG repeats and TARDBP-dependent expression of HDAC6, ATG7 and VCP which are involved in clearance of protein aggregates (PubMed:25678563).  Plays an important role in platelet activation and aggregation (PubMed:24429998).  Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (PubMed:24429998).  Binds heparan sulfate glycosaminoglycans (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A, SP18.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Nucleus. Note=Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.
Protein: SEM6B_RAT
Sequence: MWTPRAPPPRPALLFLLLLLLRVTHGLFPDEPPPLSVAPRDYLSHYPVFVGSGPGRLTPAEGAEDLNIQRVLRVNRTLFIGDRDNLYQVELEPSTSTELRYQRKLTWRSNPSDIDVCRMKGKQEGECRNFVKVLLLRDESTLFVCGSNAFNPICANYSMDTLQLLGDNISGMARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVILAVFSTPSNSIPGSAVCAFDMNQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASNALPDEILNFVKTHPLMDEAVPSLGHSPWIVRTLIRHQLTRVAVDVGAGPWGNQTIVFLGSEVGTVLKFLVKPNASVSGTTGPSIFLEEFETYRPDRCGRSSSAGEWGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQLYSGCMKNCIGSQDPYCGWAPDGSCIFLRPGTSATFEQDVSGASTSGLGDCTGLLRASLSDDRAGLVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGGSEAVLSVSRLGERRGTGTGGRGGAGGGPGGPPEALLAPLMQNGWTKAALLHGGPHDLDSGLLPTPEQTPLPQKRLPTTHPHAHALGPRAWDHSHALLSASASTSLLLLAHTRAPEQPPVPTESGPESRLCAPRSCRASHPGDFPLTPHASPDRRRVVSAPTGPLDSSSVGDDLPGPWSPPATSSLRRPGPHGPPTAALRRTHTFNSGEARPGGHRPRRHAPADSTHLLPCGTGERTAPPVP
What is the function of this protein?
Functions as a cell surface repellent for mossy fibers of developping neurons in the hippocampus where it plays a role in axon guidance.  May function through the PLXNA4 receptor expressed by mossy cell axons.
What are the official names of this protein?
Semaphorin-6B, Semaphorin-Z, Sema Z.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.