PharMolix/UniProtQA huggingface dataset:
Protein: NHAA1_PSEP1
Sequence: MEGLQPVRSLFTRFFQLEAASGLLLIAAAVLALIINNSPLSYLYGGLLDVPVAVQVGALNIAKPLLLWINDGLMALFFLLIGLEVKREVVDGHLSKPSQVILPATAAVGGMVVPALIYWFINRDNPAAVAGWAIPTATDIAFALGVLALLGKRVPVSLKLFLMTLAIIDDLGAIIVIALFYSGTLSSVSLLLAAACLLVLVAMNRLGVIKLGPYMIVGLILWVCVLKSGVHATLAGVALAFCIPLRTRNAESSPLLALEHALHPWVAYAILPIFAFANAGVSLAGMTVDSFTHPVPMGITVGLLLGKTVGVFGLTWVAVKLRLAALPAGAGWGQILGVAILCGIGFTMSLFVGSLAFAPGSSEYAGMDRMGILTGSFFAAVIGYAVTAMASRKTNVA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STUA_NEUCR
Sequence: MNPNTPADVYYGQMSQGSSMPVTTVPSHSHYASQQPPPLLQPGSTYAHQYGTPQYGYANALSSPASIPPSLPPSMNSMAGQSVLPLPGSGSMNPAVYASGGFDTTGQVAPPGMKPRVTATLWEDEGSLCFQVEARGICVARREDNAMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPFERALDFANKEKITELLYPLFVHNIGALLYHPTNQSRTSQVMAAAEQRRKDSHGQLRGPPGLPSLQQHHHHHSMLPGPPSLPSHPSMGRPALDRAHTFPTPPTSASSVMGPMGNSDGYQWSQQSMSGTQGNSSLSLDTSLGSNARSMPSTPATTPPGSTIQSMQNYPPVSQSYESSRQMYQGQSAQQAQYQSQQHYSSQPQHQERPVYSQSSYIKNDMGPPSGRPTGQSNDASDSKPPTGMIHQGQGQSDPGTHAGSEEDDDANNEAEYTHDSGGYDANRGSYNYNTQAVNSLPHDHGLAPEIGGSPHQAGSGRATPRTAAAPSSYYSAQGYHTPPRGQPSSSLYNVMSNERTGSNGTQGNEMYAGQADMPSSLPNGYSAQPSVMNGSSGGLKRGRDDDDDGGRPTTSAPNLGPGMDMKRRKTMMDGGSLPSPTYTATIAQAAPSAIAAHRRR
What is the function of this protein?
Transcription factor that regulates asexual reproduction (PubMed:8913744, PubMed:25550299).  Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).  Required for rapid conidial germination, normal vegetative morphology, and protoperithecium formation (PubMed:8913744).
What are the official names of this protein?
Cell pattern formation-associated protein asm-1, Ascospore maturation protein 1.
What is the protein family that this protein belongs to?
Belongs to the EFG1/PHD1/stuA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PNX78_SCOMU
Sequence: MGIRPTLQTNPLVDLLISTSQTQLQNAGLPFPPRSFGCLLVRHSPGCLPGSLWNLPRSRLPSCLPICLPRCRCWLNRERWRKGDDVFSDFCTKFVSTLIGPTSFAFRFVEFFYL
What are the official names of this protein?
Putative neurotoxin 7, Putative neurotoxin 8.
What is the protein family that this protein belongs to?
Belongs to the scolopendra neurotoxin 8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_ORITI
Sequence: MPTNNQLVRCGRKSKIRASKSPALNGNPFAKGVCVLVKTITPRKPNSALRKMARVRFRNGTCVNAYIPGEGHNLQEHSTVLVRGGRVPDLPGVRYHIVRGVYDTQGVKNRKQGRSRYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GAG_HV1LW
Sequence: MGARASVLSGGKLDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEECRSLYNTVATLYCVHQRIEIKDTKEALDKIKEEQNKSKKKAQQAAADTGHSSQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRNQRKIVKCFNCGKEGHIARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSYKGRPGNFLQSRPEPTAPPEESFRSGVETTTPPQKQEPIDKELYPLTSLRSLFGNDPSSQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: SYTM_RAT
Sequence: MGLCLRWRRLGFPLPGFRRCELHTVREAPIPTPPHWLAERFGLFEELWTAQVKRLASMTQKKARTIKISLPEGQKVDAVAWNTTPYQLAQQISSTLADTAVAAEVNGELYDLDRPLETDCHLRFLTFDSPEGKAVFWRSSAHVLGAAAEQHLGAVLCRGPSTESGFYLDFFLGKERTVRSTELPTLERICQEIITAAQPFRRLEASRGQLRQLFKDNHFKLHVIEEKVTGTTATVYGCGMSVDLCQGPHLRHTGQIGALKLLTNSSALWRSSEAPETLQRVSGISFPKAELLRNWEARREEAELRDHRRIGKEQELFFFHELSPGSCFFLPRGTRIYNALVAFIRAEYARRGFSEVKTPTLFSTKLWEQSGHWEHYRAHMFSLKPPGTDGVDSSQSGHPARCPKDTLALKPMNCPAHCLMFAHRPRSWRELPVRLADFGVLHRAEASGSLGGLTRLWRFQQDDAHIFCAPSQLEAEIRGCLDFLRSVYSVLGFSFHLALSTRPPGFLGEPHLWDQAEKVLQQALEEFGEPWNLNPGDGAFYGPKIDVHLHDALGRPHQCGTIQLDFQLPLRFDLQYKGPAGAPECPVLIHRAVLGSVERLLGVLAESCGGRWPLWLSPFQVVVIPVRTEQEDYARQVQQCLQAAGLVSDLDADCGLTLSRRVRRAQLAHYNFQFVVGQREQSQMSVNVRTRDNRQLGERGLAESVQRLLELQDARVPNAEELF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged tRNA(Thr) via its editing domain.
What are the official names of this protein?
Threonine--tRNA ligase, mitochondrial, Threonyl-tRNA synthetase, ThrRS, Threonyl-tRNA synthetase-like 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: YQGF_ALISL
Sequence: MSSRTIMAFDFGTKSIGSAIGQEITGTASPLKAFKAQDGTPNWDDIEKQIKEWQPDLIVVGLPTDLHGKELDVITPKAKKFANRLHGRFGNQVELHDERLSTVEARADLFEFGGYKALSKGNVDCQSAVVILESWFESQWG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPR1_HUMAN
Sequence: MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFAAYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYGVSITLSGRTATGQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIEKVKFLWNNNVINPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLTPC
What is the function of this protein?
May function as inhibitor of dietary triglyceride digestion.  Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro) (By similarity).
What are the official names of this protein?
Inactive pancreatic lipase-related protein 1, PL-RP1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: BI52A_XENLA
Sequence: MMSISPIVSLRRCDNEPSMPDEWRLYKLASRLRTFSNWPFTEDCACTPERMAEAGFVHCPTDNSPDVVKCFFCLKELEGWQPEDDPMDEHKKHSPSCLFIALKKKAEELTLSEFLKLDLEHTKIKMQKQMNLHIERFQAKANEVRGHLEKLDADETQ
What is the function of this protein?
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis.  The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity).  Does not appear to exhibit anti-apoptotic activity.  Plays a role in increasing blood vessel size during development.
What are the official names of this protein?
Baculoviral IAP repeat-containing protein 5.2-A, Survivin2-A, xSurvivin2A, xSvv2/SIX, xL_Survivin1, Su1.
What is the protein family that this protein belongs to?
Belongs to the IAP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis.
Protein: RDGC_XANCB
Sequence: MFFRNLTLFRFPTTLDFSEIETLLPQVQLKPVGPLEMSSRGFISPFGRDEQDVLSHRLEDFLWLTVGGEDKILPGAVVNDLLERKVAEIEEKEGRRPGGKARKRLKDDLIHELLPRAFVKSSRTDAILDLQHGYIAVNTSSRKSGENVMSEIRGALGSFPALPLNAEVAPRAILTGWIAGEPLPEGLSLGEECEMKDPIEGGAVVKCQHQELRGDEIDKHLEAGKQVTKLALVMDDNLSFVLGDDLVIRKLKFLDGALDQLEHSEGDGARAELDARFALMSAEVRRLFLLLEDALKLSKAEA
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DXR_TREPA
Sequence: MSVRRVVVLGITGSIGAAALKLLRRFPDRFLLVGASGHRQTEYARALAREFSLSDITMTGSCSEQEGRARIKRLLSSCEAEVVVNGIAGAAGLFASLEVLKTRCTLALANKESVVLAASLLHAAARESGATIVPVDSEHAAIFQLIAAHGAHAVAQVVLTASGGPFRTFSKECLAHVTVEDALQHPTWRMGKKISVDSATLANKALEVIEAVQFFRIPVDRVTVVVHPQSIVHALVQCHSGETYAQLSVPDMASPLLYALLYPDAPPAYQTPLDFTSGLSLHFEPPRVDDFPLLRMGFDVARAQRAYPIAFNAANEEAVRAFLQRNIGFLDIAHVTAQALQEDWRAIPQTFEEVMACDTRARMCARTCIAQRWRER
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: EPB1A_XENLA
Sequence: MELNVLLLLLCLSGGQVGAVEETLMDTRTATAELGWTANPSSGWEEVSGYDENLNTIRTYQVCNVFGPKQNNWLLTTFIPRRGAHRVYVEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSNIENKISTFWNESPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRSGFYLAFQDYGACMSLLSVRVFFKEMPSVVQNLLVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGKCTCKAGYEPENHVVCKACPAAMFKANQGMGICAQCPANSRSTSEASPICICRNGYYRADFDTPEAPCTSVPSGPRNVISIVNETAITLEWHPPRETGGRDDVDYNIVCKKCRADRRACSRCDDNVDFVPRQLGLTDTRVFISNLWAHTPYTFETQAVNGVTNKSPFPPQHVSVNITTNQAAPSSVPIMHQVKATMKSITLSWPQQEQPNGIILDYEIRYYEKDHHEFNSSLARSQTNTARRTGGRVWMFMSVQVRARTVAGYGKFSSKCGFQTLTAEDYKSELREQLPLTGSAAAGVVFIVSLVAISIVCSRKRTYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPSKREISVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAQEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWTMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRLAEIVNTLRPMIRNPASLKTVATIPAVPSQPLLDRSIPDISAFTSVDDWLSAIKMGQYRDNFLSSGFTSLQLVAQMTSEDLLRIGITLAGHQKKILNSIQSMRVQITQSPTSIA
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  May play a role in axon guidance during nervous system development.  May also play an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation.  More generally, may play a role in targeted cell migration and adhesion.  Upon activation by ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.
What are the official names of this protein?
Ephrin type-B receptor 1-A, Tyrosine-protein kinase receptor XEK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome membrane. Cell projection, dendrite.
Protein: VP51_BPAPS
Sequence: MINQRVAMAEHAKLAPSSAHRWLKCPGSTALEATLPDKTSPFAEEGSAAHALAESILKMRQNPFSDGRRRTYGFDVKEYIGTYPLLKANSPQVDEEMIEHVQTYIDTVWQLANGKMLQVEERVDFSAVIGVDNSFGTADAIIVSSDELQIHDLKYGKGVKVDAQNNEQLMLYALGALHQFDLVYDFKTVRLFIHQPRLNHLSEWAVSVEDLKDFGEQAKSGAQKAMKMATLAERSGLDALPDSAFSPGVKQCLFCKAKGGLCFAQAQFVHNEVKGDFVDLTQPLAPQLSDAPKRITLLTPEKMAKLYPHVDLIESFCKALRNRVAEALHTGQSVPGFKLVTGKQGNRTWGDEREAETLLKGAKLKQEQIYHKKIISPPQAEKLLKKDKPHRWAKLEALIERADGKPVIAPESDPRPAIITTPLNDFDDVTEAALVDKSI
What are the official names of this protein?
Putative protein p51.
Protein: PGK_GLOC7
Sequence: MPKKTIANLSRADVEGKRVLVRVDFNVPLDDAGNITDDTRIRAALPTIQDLISKGAKVILCSHFGRPKGKVVESMRLTPTAKRLSELLGQDVVMCDDCVGASVTEAVNKLENGQVALLENLRFHAEEEGNDPEFSKQLAANADLYVNDAFGTAHRAHASTEGVTHYLSPSVAGYLIEKELNYLQSAIENPQRPLAAIIGGSKVSSKIGVIETLLEKCDKLLIGGGMIFTFYKARGLSVGKSLVEEDKLELAKSLEAKASEKGVQLLLPTDVVVADAFDANANDKTVKIEEIPDGWMGLDIGPDSVKLFQDALADCKSVIWNGPMGVFEFDKFAKGTEAIAYTLETLTGKGATTIIGGGDSVAAVEKVGVADKMSHISTGGGASLELLEGKVLPGIAALDEA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_ACAM1
Sequence: MVASLSGAQIRQTFLDFYAAKGHKILPSASLVPEDPTVLLTIAGMLPFKPIFLGQREAEVPRATTSQKCIRTNDIENVGQTARHHTYFEMLGNFSFGDYFKEQAIAWAWELSTEVYKLPPERIVPSVFEEDDEAFAIWRDKIGIPEHRIQRMGAEDNFWASGPTGPCGPCSELYYDFYPEKGDDKIDLEDDTRFIEYYNLVFMEYNRDSDGKLAPLKNKNIDTGLGLERMAQILQGVPNNYETDLIFPIIETAAKIAGIKYKKSKAKTKTSLKVVGDHVRSVVQMIADGITASNVGRGYVLRRLIRRVVRHGQLIGIDGAFITQVAETAIASLEVAYPEVREREKIIKTELEREEAQFLKTLNRGEKLLGEIMAKKPKQISGKDAFDLYDTYGFPLELTQEIAAEQGLTVDEDGFAKAMKEQQDRGRSAHKTIDLTVQSALEQLAATVHPTDFLGYTDFSAKAKVAALLVKGETVDQASAGSEVQIALDQTPFYAESGGQIGDRGYLNGKDVVVRIEDVQKESDIFIHYGRIERGTLEVGDKLTAQIDLACRRQVQAHHTATHLLQAALKNIVDESIGQAGSLVAFDRLRFDFNYNQAVTPEQIQEIETQINTWIAEAHTTETEVMPIAEAKAKGAVAMFGEKYGAEVRVMDVPGVSMELCGGTHVKNTSEIGLFKIVTEAGVASGVRRIEAIAGPAVLEYLNVRDAVVRDLSDRFKAKPEELPERITTLQADLKTAQKQLDTLKAQLALVKSEQLLDQAEPAGEVKVLVSQLEGVDSESLKTAAGRLLQKLGEGAVVLGSVPAEGKVSLVAAFSPKVIEQGLQAGKFVGAIAKQCGGGGGGRPNLAQAGGRDPSKLADALDDAQKQLLAQLK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHAR3_MOUSE
Sequence: MAASEDGSSCLVSRGRSQSDPSFLSDSSATSTDAGENPDEMDQTPPARSEPLVSGIRTPPVRRNSKLATLGRIFKPWKWRKKKNEKLKQTTSALEKKMAGRQGREELIKQGLLEMMEQDSENKACSPKEGSQPVQSEPPAGEQETLTSEGAQPGSPSASGTDQVSQDELLSSDAHLDDTANIPSASTAEEADAGSLLPTTDEPSQALAGSDSLDSPPRSLERSVSQLPSPPLLPTPPPKASSKATKNVTGQAALFQGPSMKNNEPALRGQLATPTGSPHVTTVHRPLPPSRVMEELHRALATKHRQDSFQGRECRGSPKKRMDVRLSRTSSMERGKERDEAWSFDGASENKWTATKDSEENKENLMLSSELKDDMLLYQDEEALNDSIISGTLPRKCKKELLAVKLRNRPSKQELEDRNIFPRRTDEERQEIRQQIEMKLSKRLSQRPAVEELERRNILKQRNDQTEQEERREIKQRLTRKLNQRPTVDELRDRKILIRFSDYVEVARAQDYDRRADKPWTRLSAADKAAIRKELNEYKSNEMEVHASSKHLTRFHRP
What are the official names of this protein?
Phosphatase and actin regulator 3, Scaffold-associated PP1-inhibiting protein, Scapinin.
What is the protein family that this protein belongs to?
Belongs to the phosphatase and actin regulator family.
What are the subcellular locations of this protein?
Nucleus matrix. Note=Localized to the nuclear matrix-intermediate filament scaffold.
Protein: NQOR_CAUSK
Sequence: MPKVLVLYYSAYGHIETMANAVAEGARAAGATVDIKRVPELVSEEIAKKSHYKLDQAAPIAKIDDLADYDAIIVGTGTRFGRMSSQMAAFLDQAGGLWARGALNGKVGAAFTSSATQHGGNETTLFSIITNLLHFGLTIVGLPYSHAGQMTLEEITGGAPYGATTIAGGDGSRQPSQIELDGARHQGELVAKTAAKLFG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: RL11_STRGG
Sequence: MPPKKKKVTGLIKLQINAGAANPAPPVGPALGQHGVNIMEFCKAYNAATESQRGMVVPVEITVYEDRSFTFVTKTPPAAKLILKAAGVDKGSGEPHKTKVAKLTAAQVREIATTKLPDLNANDLDAASKIIAGTARSMGITVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SSRP_LISMC
Sequence: MPKGDGKLVAQNKKARHDYAIEETFEAGIVLQGTEIKSVRNARVNLKDSYARIDKGEIFLHNMHISPYEQGNRYNHDPLRTRKLLLHKKQISRLIGETKESGYSIVPLKMYIKDGYAKVLIGVARGKKKYDKRQDLKQKEAKRDIERAFKERQQ
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SYDP_YERP3
Sequence: MDLNISTALRSFTQRYIDLWQQQTGHLPASKDLYGVPSPCIVATGEDQVFWQPQAFLPEATLTNIERALEIQLHPDIHDFYTQQYAGDMMADLGNHRFTLLQVWSEDDFIRLQENLIGHLVTQKRLKLSPTLFLATTSSEMTMASLCNVSGNVVLEQFGSDKRTLLASTLSHFLDALRPVLPE
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: RS7_SHEWM
Sequence: MPRRRVVGQRKILPDPKFNSELLAKFINVIMQDGKKSTAEKIIYKALDTVAEKKSEDHLVILEAALENVRPSVEVKSRRVGGSTYQVPCEVRPVRRNALGMRWLVEAARKRGEKSMALRLAGELLDASENKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: OPPC_LACLS
Sequence: MTEKKHKNSLSLVHSIKEELKKDKLAMISTIFLVAVFLIVYIYSMFLKQSNYVDVNIMDQYLAPLTTGHLLGTDNGGRDIIMMLMISARNSFNIAFAVTLITLVVGNILGVITGYFGGRFDLIFMRFTDFVMILPSMMIIIVFVTIIPRFNSWSLIGIISIFSWIGTTRLIRARTMTEVNRDYVQASKTSGTSDFKIMFREIWPNLSTLVIAEATLVFAGNIGLETGLSFLGFGLPAGTPSLGTMINEATNPETMTDKPWTWVPATVVILIVVLAIIFIGNALRRVADQRQATR
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Oligopeptide transport system permease protein OppC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIG_PSEE4
Sequence: MSNVDHAEIAKFEALAHRWWDRESEFKPLHDINPLRVNWIDERVSLAGKKVLDVGCGGGILSEAMAQRGATVTGIDMGEAPLAVAQLHQLESGVDVEYRQITAEALAEEMPEQFDVVTCLEMLEHVPDPSSVIRACYRMVKPGGQVFFSTINRNPKAYLLAIIGAEYILKMLPRGTHDFKKFIRPSELGAWSRVAGLEVKDIIGLTYNPLTKHYKLSNDVDVNYMIQTLREE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: CAIC_SHISS
Sequence: MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTTNLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATVTECIPMMIRTLMAQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYCDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RNH_SALCH
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFSEGYTLTTNNRMELMAAIVALEALKEHCEVTLSTDSQYVRQGITQWIHNWKKRGWKTAEKKPVKNVDLWKRLDAALGQHQIKWVWVKGHAGHPENERCDELARAAAMNPTQEDSGYQAEA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.