PharMolix/UniProtQA huggingface dataset:
Protein: FABD_MOUSE
Sequence: MSARVARAGWAWRSWGRRAASSLREPPPDAVDVAELLRDSSVAEEGAQEAVARRRPPSQCSVLLFPGQGCQAVGMGSGLLHLPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIDNCVAAAGFSVGEFAALVFAGAMDFSEGLYAVKARAEAMQEASEAVPSGMLSVLGQRQSNFSFACLEAQEHCKSLGIENPVCQVSNYLFPDCRVISGHLEALQFLRRNSAKYHFRRTKMLPVSGGFHTCLMEPAVDPLMKVLGSINIKKPLVAVHSNVSGQKYTHPQHIRKLLGQQVVSPVKWEQTMHSIYERKKGMEFPSTYEVGPGQQLGSILKCCNRQAWKSYSHVDVMQNIMDPDP
What is the function of this protein?
Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1).  This suggests the existence of the biosynthesis of fatty acids in mitochondria.
What are the official names of this protein?
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial, MCT, Mitochondrial malonyltransferase, [Acyl-carrier-protein] malonyltransferase.
What is the protein family that this protein belongs to?
Belongs to the type II malonyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NRTC_SYNE7
Sequence: MSVFLAVDHVHQVFDLPGGGQYIALKDVSLNIRPGEFISLIGHSGCGKSTLLNLIAGLAQPSSGGIILEGRQVTEPGPDRMVVFQNYSLLPWRTVRQNIALAVDSVLHDRNRTERRTIIEETIDLVGLRAAADKYPHEISGGMKQRVAIARGLAIRPKLLLLDEPFGALDALTRGNLQEQLMRICQEAGVTAVMVTHDVDEALLLSDRVVMLTNGPAAQIGQILEVDFPRPRQRLEMMETPHYYDLRNELINFLQQQRRAKRRAKAAAPAPAVAASQQKTVRLGFLPGNDCAPLAIAQELGLFQDLGLSVELQSFLTWEALEDSIRLGQLEGALMMAAQPLAMTMGLGGHRPFAIATPLTVSRNGGAIALSRRYLNAGVRSLEDLCQFLAATPQRLRLAIPDPIAMPALLLRYWLASAGLNPEQDVELVGMSPYEMVEALKAGDIDGFAAGEMRIALAVQAGAAYVLATDLDIWAGHPEKVLGLPEAWLQVNPETAIALCSALLKAGELCDDPRQRDRIVEVLQQPQYLGSAAGTVLQRYFDFGLGDEPTQILRFNQFHVDQANYPNPLEGTWLLTQLCRWGLTPLPKNRQELLDRVYRRDIYEAAIAAVGFPLITPSQRGFELFDAVPFDPDSPLRYLEQFEIKAPIQVAPIPLATSA
What is the function of this protein?
Part of the ABC transporter complex NrtABCD involved in nitrate uptake (PubMed:7767600, PubMed:8437564).  The complex is probably also involved in nitrite transport (PubMed:7767600).  Probably responsible for energy coupling to the transport system (PubMed:7767600).
What are the official names of this protein?
Nitrate import ATP-binding protein NrtC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS19_DEHM1
Sequence: MSRSVKKGPALCPKLMKKVEVASATNQKSIIKTWARWSTITPLMVGLNVGVHDGRRHVPIYITENMVGHRLGEFTTTRNFRGHAKAEKVSQVK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: KDPB_SALPK
Sequence: MSRKQLALFEPVLLVQALTDAVKKLSPRAQWRNPVMFVVWAGSVLTTLLTLAMVTGQIAGSALFTGVISLWLWFTVLFANFAEALAEGRSKAQANSLKGVKKTAFARRLRAPRHDAQADNVPAAELRKGDIVLVKAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIACSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASDFIPARGVDERALADAAQLASLADETPEGRSIVILAKQRFNLRERDMQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVESNGGHFPADVEQNVENVARLGATPLVVVEGARVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNVMGLHSPNSAILSAVIFNALIIIFLIPLALKGVSYKPLSASAMLRRNLWIYGLGGLVVPFIGIKVIDVLLTLLGLA
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF2P_THEVO
Sequence: METKSSTSLPAKKLRQPIVCVLGHVDHGKTTLLDIIRGTAVANKEPGGITQRIAATTVDINKILKATEKLNNKGMKIPGLLFIDTPGHVAFSNMRARGGALADIAVLVIDINEGIMPQTVESIDILKKFKTPFIIAANKIDLIPFFTDVKTNLFTEFIRKQRQEYVNELDARIYNIVNKLYEYGLNSDRFDRISDFTKTIAIVPVSAKKNIGVPEILMVLAGLAQRFLESEIEYKDINGHATIIEVRREESAGIALDAVLYQGTISVGDTVAVNTKTGPVTTKVKALFVNTGKSQRSLKEVETVSAAEGIRVLISDKLDVISGSPLIVVKGNMEQVMKEIEEASKVDIPLDENGIYVKAEAIGSLEAISYELNKQGIKIRAAAVGDITKRDVMDVQTLQDPLNRIIIGFNVSILPEAKDAIESSDVGVITGDIIYKIVEDTQKWIEERKKQLSQKRKEAMPVPAKIRILPQYIFRASKPVIVGIRVETGQIKVGDNLIRSDGKYAGTIKSIRNDEVSVRYQDAPAEVAVAIDNVTLNRQIFPDDVLYVDIPESVVKELRKAPMEKEIMDTLEEIIKIKRKENPFWGTKV
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: 6PGL_ECOHS
Sequence: MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: CYB_LEPCU
Sequence: MTNIRKTHPLLKIINNSLVDLPAPSSLSAWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNVGILLLSAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLTMLTALSALVLFNPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPMLHTSKQRSMMFRPLSQCLFWLLVAILLTLTWIGGQPVEYPYVIIGQTASILYFLTILIFMPLVSIMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LANM_STRMG
Sequence: FKSWSFCTPGCAKTGSFNSYCC
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
What are the official names of this protein?
Lantibiotic mutacin B-Ny266.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
Protein: MED20_XENLA
Sequence: MGVTCVSQVPLAEGKSVQQTVEILTRKLEQLGAEKQGTFYVDCETYHTAGASMGTPGQAGKLLYVMHNSEYPLSTFALFENGPCLVADLNLDVLMVKLKGFFQNAKANKMETRGTRYQYCDFLVKIGTVTVGQSGRGITVEVDYCPCAVPGDCWNLMMEFMQSFMGSHAPSVPPVFSAKHDPLYTPADTMVQYMELLNKIRKQQVTVAGMR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, TRF-proximal protein homolog.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 20 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YDEH_BACSU
Sequence: MNHIKWLSDLKKAGLLALGKGVITLLKRFSLVIVTLMMSIVVVLAAAKESPGDHVISFDEPIILMISIGIVVFLLIPPLVMSFFGNLVVRIISGVYQCFIVFTFLGLIPIGFLIPNGFLTILVSIAGTLVSIASVAVTLCIGKNKKDI
What are the official names of this protein?
Uncharacterized membrane protein YdeH.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSB9_MUSPL
Sequence: MLRAGAPTAGSFRTKEVHTGTTIMAVEFDGGVVVGSDSRVSAGEAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAAYQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHLIVAGWDQREGGQVYGTMGGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTSEECRRFTTNAITLAMNRDGSSGGVIYLVTITVAGVDHRVILGDELPKFYDE
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  This subunit is involved in antigen processing to generate class I binding peptides.
What are the official names of this protein?
Proteasome subunit beta type-9, Low molecular mass protein 2, Macropain chain 7, Multicatalytic endopeptidase complex chain 7, Proteasome chain 7, Proteasome subunit beta-1i, Really interesting new gene 12 protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CHL1_PICGU
Sequence: MNRDDPRLTYNHPYKPYDIQVQLMDAIYDTIQNKYKVGLFESPTGTGKTLSIICSSMTWLRNYKKTQDHSTMGSNSSNDNDPNQTSDSDEEPDWVKEAHIKNIRSRTSGLAIDYERHLEELSQTPHAGHTVELGQRTHKRKKRATNDDDFLPDDYNSDTDSNSVETKNAKLQQEINQIMKRVDGSDGKTPGFVNTCPVTIFFSSRTHSQLSQFAHQLSITSFESSLGEIAERIKFMPLSSRKQLCIHPKVSSLSSVSAVNDACVELQQKSDKRCEFMPRVNNPESDQLVQRFADYSFAVIKDIEELHELGADLKVCPYYASRRNIENSEIIALPYQMLLQQATRKSLGLSIKDSIVIIDEAHNLLDVISSINSVSITRKELSSVIASLKLYYNKFTKRLNSGNRIHLMKLIKLCSLVETYIKNCEIQNKCVPGSDVLIDELFQGSTGDLLNIHRIEKYLDKSKIAYKIQTYIEQSREESDEKQASSPLLFKVTAFLKSLVNPSKEGRFFWDKINDDTEIKYLLLDPSEMFRDVVESARCVLLCGGTMEPVEDYYRYLFPYVPGEKIKKFTCGHIVPQENIEVLTVSSRKTTVFDFSYHKRNDPSMLRELALSLQDICERVPNGIIVFAPSYKYLNQLISTWRKDGNLAKISTLKQVFLESSDSTSIESILRDYGAAARGSGAILFSVVGGKMSEGVNFSDELARAVIMLGLPYPNAFSGELIAKRKFIEETTLSKGGTQAMAKKNSREYYENICMRAVNQSVGRSIRHANDYSVIVLFDTRYNSSHIQSKLSGWMRSSIRPERESFDMTLERIADFFAAKTLTKR
What is the function of this protein?
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity).  May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).  Has a specific role in chromosome segregation during meiosis II (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase CHL1, Chromosome loss protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: COX6C_PIG
Sequence: MATSSLTKPQMRWPSGPRRLRFHIVGAFIVSLGVATFYKFAVAEPRKKAYADFYRNYDSMKDFEEMRKAGIFQSAK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6C, Cytochrome c oxidase polypeptide VIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6c family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: CAP3_ADE12
Sequence: MQRPAIIAERAPNLDPAVLAAMQSQPSGVTASDDWTAAMDRIMALTARSPDAFRQQPQANRFSAILEAVVPSRTNPTHEKVLTIVNALLDSKAIRKDEAGLIYNALLERVARYNSTNVQANLDRMGTDVKEALAQRERFHRDGNLGSLVALNAFLSTQPANVPRGQEDYTNFISALRLMVTEVPQSEVYQSGPDYFFQTSRQGLQTVNLTQAFKNLQGLWGVRAPVGDRSTLSSLLTPNSRLLLLLIAPFTNTNSLSRDSYLGHLVTLYREAIGQAQVDEQTYQEITSVSRALGQEDTGSLEATLNFLLTNRRQQVPPQYTLNAEEERILRYVQQSVSLYLMREGATPSAALDMTARNMEPSFYASNRAFINRLMDYLHRAAAMNGEYFTNAILNPHWLPPPGFYTGEFDLPEGNDGFLWDDVTDSLFSPAVIGHHGKKEAGDEGPLLDSRASSPFPSLTSLPASVNSGRTTRPRLTGESEYLNDPILFPVRDKNFPNNGIESLVDKMSRWKTYAQERREWEERQPRPVRPPRQRWQRRKKGAHAGDEGSDDSADDSSVLDLGGSGNPFAHLRPQGCIGSLY
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid exterior which mediates the interactions between the hexons, including the peripentonal hexons, and reaches all the way to the penton vertices.  Two hexon linking proteins IIIa, one from each facet, stabilize the unique edge interface between a pair of facets.  As the virus enters the host cell, hexon linking proteins IIIa are shed concomitant with virion acidification in the endosome.  During virus assembly, seems to play a role in the serotype specificity of the packaging of viral DNA via its interaction with packaging protein 3.
What are the official names of this protein?
Pre-hexon-linking protein IIIa, Capsid vertex-specific component IIIa, CVSC, Protein IIIa, pIIIa.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-linking protein IIIa family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Surrounds the border of each facet on the capsid exterior. Present in around 60 copies per virion.
Protein: COAE_SHIBS
Sequence: MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQATREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRLB_DICDI
Sequence: MGGDIHLCSMILGKNHLIFLYFANLFGSTLSFLATIITIVFYLVKKYIQNKSFRENPHQYCHQHQYFDSSKLNEINNSGVGSYSSTPISIQNNNNKNNNLPKQKNNEKQPLINKNHNNYCNYSTSATSSSSSSSSFSSTNSGSSYEYQQPQKNQQTLSSSDKNNTIPSTNTKYEIELSIPQFKGNKCGPNCLLFSNIPQIKNALEQKKNPKKIDTLIFYLSISDFIAVSGIIIEQLIIIFNKEISKSIGFCIGERVSIHFGLLATLFWSNCIAYYLLRETYELKPYNIRFVYFHIVCWGMALIGVASLFFSKIITVSNIDQGGSWCSVSSSYQLYFWVIPLFVSFTWNLICYCLIYRKFNKIIGIYGIQSVQIKTIIIRKLSFYLLAFLITWVWDVINNSIFLYEGKCPPFALWILQEFFSSGYGFFNSLAYAVTTRFYSRK
What is the function of this protein?
Receptor for cAMP.
What are the official names of this protein?
Cyclic AMP receptor-like protein B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 5 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL31_VESOH
Sequence: MKTSIHPNYNDVQIICSCGNTFKTRSTIDKKELHLDVCSSCHPFYTGKQKIMDSAGRVEKFKSRYASFKR
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: MCM8_HUMAN
Sequence: MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFISALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM
What is the function of this protein?
Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR) (PubMed:23401855).  Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity (PubMed:26215093).  Probably by regulating the localization of the MNR complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs (PubMed:23401855).  The MCM8-MCM9 complex is dispensable for DNA replication and S phase progression (PubMed:23401855).  However, may play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC) (PubMed:15684404).  Probably by regulating HR, plays a key role during gametogenesis (By similarity).  Stabilizes MCM9 protein (PubMed:23401855, PubMed:26215093).
What are the official names of this protein?
DNA helicase MCM8, Minichromosome maintenance 8.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
Protein: FLET_LIMFT
Sequence: AGPVSKLVSGIGL
What are the official names of this protein?
Fletcherin.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGI_DESPS
Sequence: MFFSRKIRSLLLTPKRRWSLILTLCLIFTGINFSTSNDVQASRIKDIAQLHGVRSNQLIGYGLITGLNGTGDDMKKSAFTLQAIYNMMTRSGITLNPSEMKSIKIKNVAAVMVTASLPPFASSGSKIDIQVSSMGDAKSLAGGTLLMTPLKGVDNRVYAIAQGPLAIGAFSFGGKSAQAQKNHPNAGRIPDGATVEDTVLVDIGADGTLTYQLANADFTTANNMTRAINKKFGKDTAYPLDSGSVTINIPPHFSKRVVQFVANVESIDITADSVARVVVNERTGTVVMGQNVRLSTVAVSHGNLNLIIRESFDVSQPAPLADGETVITPSTEISVTEEEGQLVVLNMKNDVSIGEIANALNAIGATPRDLIAIFQAIKAAGAMHGELIVL
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: TRM44_KLULA
Sequence: MTSNTLHYTVEKSSILGPEWQSLYSTAEPVDFDKSHFEQAMLNVIRQPNVNSTVILRADMLIDNEYDLESGSCVKSEKKDIALGSDEGILKVNIDDLAPRSVPIALADVTTKFQFVRRIVPRNPFKDAIINQTCLVMNSNSDASTSLVIYIPHFDNAELCPFYIPQVAAVGILLHDHQLSVHYIPFAGQKELLFDPKQRVVRTAFRLLQTAYKHSKGVKDGYAKRVMHDVVVDKVLFQDQYIHLKKKYSKFLVDNWAESTDPKKHVFEDIAIAAFLIELWKKIYGAENTTNKMQFRDLGCGNGVLCYILIQEGFKGLGIDARQRKSWSIYPAEVKRCLKEQVIIPSVLLRPHPTMKLHAPHLQHNGRFFPMQLVSPQLIAPATVMYSSADLLQSPQVNIAEFPPDTFIIGNHSDELTCWIPLLGYPFMVIPCCSHNLSGNRIRYAVRDVERAKKLGNSTYQGLVDRVEYLADRVGWKTEKEMLRIPSTRNAAIIGYKNDKLNEFPTDEIYSILMEEGGADGWVANTMNLMKSNPRGH
What is the function of this protein?
Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
What are the official names of this protein?
tRNA (uracil-O(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TRM44 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_XYLFT
Sequence: MDSSSFSFSHLDRLEAESIYILREVVAEFRNPVLLYSVGKDSSVLLHLLLKAFAPAPPPIPLLHVDTRWKFREMIAFRDRRVAETGVQLRVHINLEGVAQEINPITHGAAVHTDIMKTQGLRQALEQGQFDAAIGGARRDEEKSRAKERVFSFRNAHHRWDPKNQRPELWNVYNARIHPGESVRVFPLSNWTELDVWLYIYREQIPVVSLYFAAPRPVVERDGMLILVDDERLPLHPGEVSKLRWVRFRTLGCYPLTGAVESRAATLEDIIAEMLVTPFSERQGRLIDYAPGASMESKKIEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: LRGB_BACAA
Sequence: MASTMTPYFGIVVSLIAYGIGTLLFKHSKGFFLFTPLFVAMVLGIVFLKVGNFTFEEYNTGGKMISFFLEPATIAFAIPLYKQVDKLKKYWWQILSAIVVGSICSVIVVFIVAKAIGLDTAVMNSMLPQAATTAIALPISESIGGIPAITSFAVIFNAVIVYALGALFLKTFRVKHPIAKGLALGTAGHALGVAVGIEMGEVEAAMASIAVTVVGVVTVVVIPMFMPFIG
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRPE_CLOB8
Sequence: MEENRDVKNEELEKEEIADEVAEKDNETQESNDAAETNEASKEASENIEAAEEDQEDLVKNQEEENKKLREELDATKDRLLRLTAEYDNYRKRTAKEKEGIYSDAYVDVLKEIVPILDNLERAVAADGSIEDLKKGIEMTIKGCKDSFAKLGVEEIDATGEFDPNLHNAVMHIEDEELGKNVVAEVFQKGYKKDDKIIRHTMVKVAN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.