PharMolix/UniProtQA huggingface dataset:
Protein: MAPA_CAMJ8
Sequence: MFKKFLIFIVPILFLSACATKQDTFAQVNQISKNSQCSSCESPGGFEAKIKGLLYISDVGIQCCANKRTLDTGIALKKVYLHRFYDLKEGQKVLNAKGKKLFVDVNFNAVFYTYLKQELEARGIVVLDNNDQNSPYVSKIDLEFISYGATQDAIGLHSKLVGVLQVSDINKNKKFTIRTKQDVQGFDDLKETTFYTHLLIKQMANKAASLISEL
What are the official names of this protein?
Outer membrane lipoprotein MapA.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RS10_SHELP
Sequence: MQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTVLISPHVNKDARDQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DNLJ_YERPE
Sequence: MESIIQQINQLRTSLRHHEHQYHVLDAPEIPDAEYDRMMQQLRDLEAQHPELVTNDSPTQRVGAAPLDAFEQVKHEVPMLSLDNVFDEESYLAFDKRVHDRLKTAEPLTFCCELKLDGLAVSLLYENGELVRAATRGDGTTGENITANVRTIRAIPLRLHGDNVPRRVEVRGEVFMPQAGFEQLNEEARRKGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGLLDGGELPRSHIQCLMQFKAWGLPVSERVKLCTGSDQVIAFYRQIEQDRAGLGFDIDGVVIKVDDLALQEQLGFVARAPRWATAFKFPAQEQITQVREVEFQVGRTGAITPVARLEPVQVAGVIVSNATLHNADEIERLGLRIGDTVIVRRAGDVIPQVVGVVMEQRPDDTKEITFPSQCPVCGSDIERVEGEAVARCTGGLFCAAQRKEALKHFVSRRALDVDGMGDKIIEQLVEKQYVENPADLFQLTAGKLTGLDRMGPKSAQNLIAALEKAKQTTFARFLYALGIREVGEATAANLAAHFRTLDNLRAADIETLKSVPDVGEVVAKHVMNFLSEEHNQKVIEELEKVVSWPEPQQIVVEESDSPFAGKTVVLTGSLTILSRDEAKDRLTALGAKVSGSVSKKTHLVIAGEAAGSKLAKAQELGIKVIDEAEMIRLLGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RPF1_HUMAN
Sequence: MAKAGDKSSSSGKKSLKRKAAAEELQEAAGAGDGATENGVQPPKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKEREALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKPREMDTSRRKFHL
What is the function of this protein?
May be required for ribosome biogenesis.
What are the official names of this protein?
Ribosome production factor 1, Brix domain-containing protein 5, Ribosome biogenesis protein RPF1.
Protein: RCCD1_HUMAN
Sequence: MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRLELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEAEGEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREATELNEDGSQVKRTGGAEDGAPAPFIAVQPFPALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQLQVKAVTCGPWNTYVYAVEKGKS
What is the function of this protein?
Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8 (PubMed:24981860).  Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation (PubMed:24981860).  Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8 (PubMed:28455245).
What are the official names of this protein?
RCC1 domain-containing protein 1.
Protein: LEUD_THEYD
Sequence: MKIKGKVWKFGDNIDTDAIIPARYLNTSDPKELAKHVMEDADSSFPSKVKPGDIIIAGRNFGCGSSREHAPIAIKASGIRAVIAKSYARIFFRNAFNIGLPIFEVPELIDETNEGDEVEIDMNSGQIINLTKGKKYNTKPIPPFMQELIKAGGLVEWTKKRLSMEDIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: RL22_DESHY
Sequence: MQQAKAIARYVRISPRKVRQVVDLIRGKNVSDALAILQFTPKGATEPVTKVLQSAVANAEHNYEMDTDALIVKEIYVDEGPTLKRIKPRAMGRADQIRKRTSHITVVVVEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PSTC_HAEIN
Sequence: MLTKSRKYFNQTWIESLFKQTTALFALLVFILLAAILISLVIGSWESIKRFGGSFLLETYWDPVQEQYGAIIPILGTLITAGIALFIAVPISFGIAIFLTELAPNWLKRPISIAIEMLAAIPSIIYGMWGLFVFVPLFQEHIQPVLIDNLGNLPGLELFFSGVPFGVGLFTAGLVLAIMIIPFIASVMRDVFSIVPPMLKEGAYGLGATTWEVVRQVIVPHTRIGLVGSVMLGLGRALGETMAITFIIGNSFQLPNSLFSPSTSIASAIANEFNEAGGLQKSALMELGLLLFVITTMVLILSRLMITKMQQTKGK
What is the function of this protein?
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphate transport system permease protein PstC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VNFK_AZOVI
Sequence: MSNCELTVLKPAEVKLSPRDREGIINPMYDCQPAGAQYAGIGIKDCIPLVHGGQGCTMFVRLLFAQHFKENFDVASTSLHEESAVFGGAKRVEEGVLVLARRYPNLRVIPIITTCSTEVIGDDIEGSIRVCNRALEAEFPDRKIYLAPVHTPSFKGSHVTGYAECVKSVFKTITDAHGKGQPSGKLNVFPGWVNPGDVVLLKRYFKEMDVEANIYMDTEDFDSPMLPNKSIETHGRTTVEDIADSANALATLSLARYEGNTTGELLQKTFAVPNALVNTPYGIKNTDDMLRKIAEVTGKEIPESLVRERGIALDALADLAHMFFANKKVAIFGHPDLVLGLAQFCMEVELEPVLLLIGDDQGNKYKKDPRIEELKNTAHFDIEIVHNADLWELEKRINAGLQLDLIMGHSKGRYVAIEANIPMVRVGFPTFDRAGLYRKPSIGYQGAMELGEMIANAMFAHMEYTRNKEWILNTW
What is the function of this protein?
This vanadium-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase vanadium-iron protein beta chain, Dinitrogenase 2 subunit beta, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: SBMC_PANSA
Sequence: MKTSIVERPAQHWVGYRLQGPWQETVPQGFAQLKDWVARHALQGEWMAIYYGNPQVVPPQELSVETVLTVPADFALAVGEGIQHGTLAGGHYFHTCTEVQNNDFFSAWNAFFAQLQQRSDWQVDDRPCYEHYLSDGSQSGNWLLNMYIPVRPV
What is the function of this protein?
Inhibits the supercoiling activity of DNA gyrase.  Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase.  It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
What are the official names of this protein?
DNA gyrase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISP7_SCHPO
Sequence: MLSQLIERSTQYVREASLEEQNRIMPLIDFGPYVNQEPGAHERIIQQLRAACESTGFFQIVNSPISPDVVKNAFRASKQFFELPFDEKLTLSKDMFSNRGYELMEDFVLEGEEDSSSPLEISGIDFEAGSYPGEAPLPPSSIGYVLPPSSLANGEGSSMFDADMTTSNAVAHGDESISNEFRESFYFGNDNLSKDRLLRPFQGPNKWPSTAGSSFRKALVKYHDQMLAFANHVMSLLAESLELSPDAFDEFCSDPTTSIRLLRYPSSPNRLGVQEHTDADALTLMSQDNVKGLEILDPVSNCFLSVSPAPGALIANLGDIMAILTNNRYKSSMHRVCNNSGSDRYTIPFFLQGNIDYVVAPLPGLGPSTAEPIAVEDLLRDHFQNSYTSHTTSLEVA
What are the official names of this protein?
Sexual differentiation process protein isp7.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: TMCAL_CLOP1
Sequence: MNITGIITEYNPFHLGHELHLKSSKEITNCDGVICVMSGNFVQRGLPALTDKWTRTKMALEAGVDLVVELPTLFATSSAEFFAFGAVSLLNSLNVVNNICFGSECGDIDLIKKLSEIIINEPPLFKEYLKDYLKEGLPFPKARSKALMKYLDDNNYKIDFSYLEKVLNSSNNILAIEYCKSLYKLQSSIKPFTIQRLGADYNDEKLSKNEIASASAIRKSIYTSNIEESLDFMPEYSYNLLKNTSFSDLDKMFDLVKYAIVSNPNVLKEIPEASEGIDNKIIQNIGKANSLDELINLCKSKRYSYTRLNRILCHVLLNVNKDLLSLRKSSPNYVRILGFNNKGREILKEIKKNSEINIVNKLSKAKSDSLLEFDIKATNIYSFLNPSVKINSDYLISPIIFR
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_LACLS
Sequence: MTLTQEFDTIAAISTPLGEGAIAIVRLSGTDALKIAQSVYKGKNLAQVASHTINYGHIFEEERLVDEVMVSVMRAPKTFTREDIVEINTHGGIAVTQEILQLLLRNGARLAEPGEFTKRAFLNGRIDLAQAESVMDLIRAKTDKAANIAVKQLDGSLSKMINNIRQDILESLAQVEVNIDYPEYDDVETMTSQMLLEKTAHFEQLLENLLSTAKRGKILREGLKTAIIGRPNVGKSSLLNQLLREEKAIVTDIAGTTRDVITEFANIGGVPLELVDTAGIRETDDLVEAIGVERSKKALAEADLVLLVLDASLELTDKDLELLELSKNANRIVLLNKTDLPEKLDINQISGDFIRISALKNENLSAVEEKINQIFFAGEIEAKDATVLSNARHISLVEEALKALKEANNGLALGLPVDLIQVDVTRCWQLLGEITGEAAPDELITQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN1_PSEPF
Sequence: MIEFQNVHKTYRVAGKDITALHPTSFSIENGQVFGLIGHSGAGKSTLLRLINRLEQSSGGKIIVDGEEVTALDANGLRRFRQQVGMIFQHFNLLASKTVADNVALPLTLAGELSRAEIDQRVAELLARVGLSDHAKKYPAQLSGGQKQRVGIARALATKPKILLCDEATSALDPQTTASVLQLLAEINRELKLTIVLITHEMDVIRRVCDQVGVMDAGVIVEQGSVADVFLHPKHPTTKRFVQESEQIDESEQRDDFAHVPGRIVRLTFQGEATYAPLLGTVARETGVDYSILAGRIDRIKDIPYGQLTLAVTGGDMDAAFARFTAADVHMEVLR
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBID_SHESA
Sequence: MSFKDLRSFIDHLEANGELKRISYPVDPHLEMTEIADRVLRAKGPALLFENPTNHSMPVLANLFGTPKRVAMALGKEDPLALRDVGELLAFLKEPEPPRGFKDAISKIPMFKQALNMPPKTVRNPACQQVVKTGDEVDLTQLPIQHCWPGDVAPLVTWGLTITKGPRKSRQNLGIYRQQLLGKNKLIMRWLSHRGGALDFADFKEQFPGERYPVVVALGSDPVTILGAVTPVPDAMSEYAFAGLLRGERTEVCKALSCDLEVPASSEIILEGYIDPDEMAEEGPYGDHTGYYNETDKFPVFTVTHITHRKDPIYHSTYTGRPPDEPAMLGVALNEVFVPILRKQYPEIIDFYLPPEGCSYRMAVISIRKQYPGHAKRVMMGAWSFLRQFMYTKFIVVVDDDVNCRDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPVAGLGSKMGLDATNKWEGETNREWGTPIVMDPKVKQKIDSIWDELGIDDSPTL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL24_MYCGA
Sequence: MQRIKKGDKVVIIAGKHKQKTGIVLQVFVKEQRAIVEGINMVKRHTKENAQNQKGGIIEKEAPIHLSNLALLDHKAKDVRPVKVKYGTDPKTNKKVRLSRKTNNLVGGQ
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: FB118_ARATH
Sequence: MLLYLLITCLSFFFFSKSLSFPQWASKTKNLLSFYFSKYLFTNSLHQITPDLASPVLGKMSILDLPDLPLDCILELLPPSELCTMARVCSSLRERCVSDHLWEKHLKTKWGKILGPSAHKEWQCYLSSPYHLDSPHHKTSHLGLAKIISLMRSLSSIFRDDDHRRRYPSSIPLDSTMNFYLSLETGRFWFPAQVYNRENGHVGFMLSCYDAELSYDTDTNTFQARYPPHGKRAIAVEKDVTWERIRAAPVDASPHNLYVSDSLNELKPGDHIEIQWRRNKEFPYGWWYSVVGHMESCDGNLNHCQCHNSEMMVLEFNQYTVGSRWRKTMINRRDHREKGNEEDGFYGGIRKINCKEDIEMWKRLWPSSILE
What are the official names of this protein?
F-box protein At2g26850.
Protein: CAPSD_ACLSA
Sequence: MAAVLNLQLKVDADLKAFLAAEGRPLHGKTGAILEQTLEAIFANIAIQGTSEQTEFLDVLVEVKSMEDQKVVGSFNLKEVVGLIKIFRTTSSDPNISSMTFRQVCEAFAPEARNGLVKLKYKGVFTNLFSTTPEVGGKYPELMFDFNKGLNMFIMNKAQQKVITNMNRRLLQTEFAKSENEAKMSSVTTDLCV
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What are the subcellular locations of this protein?
Virion.
Protein: HYD1D_PYRFU
Sequence: MGKVRIGFYALTSCYGCQLQLAMMDELLQLIPNAEIVCWFMIDRDSIEDEKVDIAFIEGSVSTEEEVELVKKIRENAKIVVAVGACAVQGGVQSWSEKPLEELWKKVYGDAKVKFQPKKAEPVSKYIKVDYNIYGCPPEKKDFLYALGTFLIGSWPEDIDYPVCLECRLNGHPCILLEKGEPCLGPVTRAGCNARCPGFGVACIGCRGAIGYDVAWFDSLAKVFKEKGMTKEEIIERMKMFNGHDERVEKMVEKIFSGGEQ
What is the function of this protein?
Part of a bifunctional enzyme complex that functions as an NADPH-dependent hydrogen-evolving hydrogenase with sulfur reducing activity.  May play a role in hydrogen cycling during fermentative growth.  Activity not exhibited with NAD.  The alpha and delta subunits form the hydrogenase component that catalyzes the reduction of protons to evolve hydrogen.
What are the official names of this protein?
Sulfhydrogenase 1 subunit delta, Hydrogenase I small subunit, NADP-reducing hydrogenase subunit HydD, Sulfhydrogenase I subunit delta.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSBA_SHIDS
Sequence: MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFMLSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYAQLHKMQFGQ
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATC_CERS1
Sequence: MSIDIETARRVAHLARIRVDEADLPALAGELSGILTFMEQLNEVDVEGIEPMTSVTPMRLKRRQDVVTDGDMQDKVLSNAPDAREGFFAVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RNZ_MICAN
Sequence: MEITFLGTSSGVPTRSRNVSSIALRLPQRAEIWLFDCGEGTQHQLLRSDLKSSQIRRIFITHMHGDHIFGLMGLLASIGLAGSAQDIDIYGPPGLGDYLRACAKYSYTNLANRVRVHAISPGILYEDEEFTVSCQLLKHRIPAHGYRIAEKDRPGRFDVEKANALGIPPGPIYGKLKKGETVTLPDGSKIRGQSLCGETEIGRKIAYCTDTIFCEGSIELAQNADVLIHEATFAHQDAGLAFESVHSTSTMAAQVALAAQVKLLLMTHFSPRYLPGNSLDISNLLEEARAIFPNTKLAYDFLTYEVPRNRQEMALGVK
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RBM22_PONAB
Sequence: MATSLGSNTYNRQNWEDADFPILCQTCLGENPYIRVTKEKYGKECKICARPFTVFRWCPGVRMRFKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNKEYYTQNMEREISNSDGTRPVGMLGKATSTSDMLLKLARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGINDPVADKLLKRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKWGRSQAARGKEKEKDGTTDSGIKLEPVPGLPGALPPPPAAEEEASANYFNLPPSGPPAVVNIALPPPPGIAPPPPPGFGPHMFHPMGPPPPFMRAPGPIHYPSQDPQRMGAHAGKHSSP
What is the function of this protein?
Required for pre-mRNA splicing as component of the activated spliceosome.  Involved in the first step of pre-mRNA splicing.  Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle.  Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
What are the official names of this protein?
Pre-mRNA-splicing factor RBM22, RNA-binding motif protein 22.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nearly exclusively nuclear. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol.
Protein: ALR_SHEB5
Sequence: MNPFPRAEISSSALQTNLAALRQQAPASRVMAVVKANGYGHGLLNVANCLVSADGFGLARLDEALELRAGGVTARLLLLEGFFRATDLPLLVGHDIDTVVHHSSQLEMLEQTVLSKPVTVWLKVDSGMHRLGFTPEQFSTVYDRLMACPNVAKPIHLMTHFACADEPDNTYTSVQMAAFNSLTAGLPGFRTLANSAGALYWPQSQGDWIRPGIALYGVSPVTGDCGANHGLVPAMELVSQLIAVRDHKANQPVGYGCFWTAKQDTRLGVVAIGYGDGYPRNAPEGTPVWVNGRRVPIVGRVSMDMLTVDLGQDAQDKVGDSALLWGKALPVEEVAEHIGTIAYELVTKLTPRVAVCLA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: CYSH_MYCS2
Sequence: MTDVTTSTENELRELAERGAAELADASAEELLRWTDEHFGGNYVVASNMQDAVLVEMAAKVRPGVDVLFLDTGYHFAETIGTRDAVEAVYDVHVVNVTPERTVAEQDELLGKNLFARDPGECCRLRKVVPLTNALKGYSAWVTGIRRVEAPTRANAPLISWDNAFGLVKINPIAAWTDEDMQNYIDANGILVNPLVYEGYPSIGCAPCTSKPIPGADPRSGRWAGLSKTECGLHVS
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y921_METJA
Sequence: MSVNYKSVIAMVDDALNLVEIVEEHPCPNGSEWVIYQYQRTSPLILSAWREGNKHHFVTKIGKEKLNLVPSLSAAGIEEVYIENNRVHIVYAGLAGGGVGAELRKGAKNVLEVNILEKGGGSRLGKAEVITPKMEKVIIGIDDTDTKEEGATWVLAHEIGLEVEKEGLGYYLDHTIVQLYPGNPNKTQNCVSIALSFAVYPEYKYKLDKFIKKLLKERSLSDETAMAVYYGLFPSKSMKLFALKAKKEMVKIEEAKSIALRNNIKIIPINGEGGIIGAVAALGLAEHHSLAPKLCEDIKL
What are the official names of this protein?
Uncharacterized protein MJ0921.
Protein: MTNA_ALCBS
Sequence: MAVNSAAIRWLGDHLQLLDQRCLPTETLWLDICDSQQAADAIRNMVVRGAPAIGITAAYGLALEAQIMGNDASWVTLQNAVATLADSRPTAVNLFWALERLQRYAGDLQGKALAQALAEDAEAIHREDLAANQAMGEFGADLLPSGATVYTHCNTGALATGGHGTALGIIRSAWARNQLTGVFAGETRPWLQGSRLTSWELLNDGIPVTLVADSCAGQLMQQGKIQAVIVGADRITANGDTANKIGTYNLAVLAQHHNIPFIVAAPVSTLDPALPNGSHIVIEERDANEVRNVQGKSLAPEHCPVYNPAFDITPAQLITAIVTERGVVHRPDTAKINSHLAQTKES
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: TM198_XENTR
Sequence: MLQNIDNRTVDTGQDDPFDGFCSLESERHYDVVPTVVCSLCCLFGLVYTFFGYRCFKAIMFLSGLLAGSAVIFLLCYKERIMDTQLSLELSAGIALGIGLLCGLVTMLVHSVGLFMTGLLLGLLLAIASLVGLEQFYHPPSAWIPVGLMMGSAMLFAVLTLQWQKLFTVVSTATFGAAILTVCTDYFIELMLLVQYVYDRLRLETSHPLCWYSWVILGMWPVLSVLGIVVQWKLTAEGFSHTDVIISRRQKRLQLLRIRQKDAKKRQNVASQEGTYRRKANPMKRYTGDILAPSYLQSLRERQTGTGTSMSSLSTNMQTIVDMDYECGSTVPLTATTPVIHV
What is the function of this protein?
Promotes lrp6 phosphorylation by casein kinases and thereby plays a role in Wnt signaling.  May be a membrane scaffold protein involved in the self-aggregation of lrp6 further enhancing its activity.  Required for neural crest formation.
What are the official names of this protein?
Transmembrane protein 198.
What is the protein family that this protein belongs to?
Belongs to the TMEM198 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasmic vesicle. Note=Largely located to vesicle-like structures.
Protein: ENGB_SINMW
Sequence: MSATNNQNAASVFGRPWIFIRGVPSMKFLPPEGPTEIAFAGRSNVGKSSLINALVGHKGLARTSNTPGRTQELNYFVPDGYSGEADDLPPMALVDMPGYGYAQAPKEQVDAWTKLVFDYLRGRSTLKRVYVLIDARHGIKKNDEEVLALLDKAAVSYQIVLTKTDKIKAAGVPRLLAETLEKIRKRPAAFPEVLSTSSEKGEGIEELRAAIELAVAR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PYRF_STRPG
Sequence: MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGPDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQAIKAEWAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: Y3515_METJA
Sequence: MKFFNREKEINEILLILEEEPNNIYFIYGPLNSGKSTLIREVITNRLDKSKYIPFFIDFRTRNILNVDNFIECLFEVDEKSKIDDFREYAKSLADLLVKGSEEISKYYLGMPIKVPKPFFDRIFSKRDKSADVYQYIEYLFAKLNEKGKKPILIFDELQMIREITLNGNRLLLWSLFQFLVALTKVQHLCHVFCLSSDSLFIEYIYGKAELKGGVDYILVDDFDKKTALKFMDFLAKQKNINLTNEDKELIYSYVGGKAKYIYDVIVKLKAVKDLKYILETKLEEERNHLEELLEKVEEDYEGINYDEVLEALKLFKDNYELPKSKIKRKIRIFLIKENILFLNPQKGTLKPQSYLVWNAIKRML
What are the official names of this protein?
Uncharacterized ATP-binding protein MJECL15.
What is the protein family that this protein belongs to?
Belongs to the archaeal ATPase family.