PharMolix/UniProtQA huggingface dataset:
Protein: POLN_HEVCT
Sequence: MEAHQFIKAPGVTTAIEQAALAAANSALANAVVVRPFLSRLQTEILINLMQPWQLVFRPEVLWNHPIQRVIHNELEQYCRARAGRCLEEGAHPRSINDDPNVLHRCFLKPVGRDVQRWYTAPTRGPAANCRRSALRGLPPVDRTYCFDGFSGCTFAAETGVALYSLHDLWPADVAEAMARHGMTRLYAALHLPPEVLLPPGTYHTTSYLLIHDGDRAVITYEGDSSAGYNHDVSILRAWIRTTKVTGDHPLVIERVRAVGCHFVLLLTAAPEPSPMPYVPYPRSTEVYVRSIFGPGGSPSLFPSACSTKSTFHAVPVHIWDRLMLFGATLDDQAFCCSRLMTYLRGISYKVTVGALVANEGWNASEDALTAVITAAYLTICHQRYLRTQAISKGMKRLELEHAQKFITRLYSWLFEKSGRDYIPGRQLQFYAQCRRWLSAGFHLDPRVLVFDEAAPCRCRSFLRKAATKFCCFMRWLGQDCTCFLQPIEGRVGEQGYDNEAFEGSDIDPAEEATVSIAGSYIVTGSQLQPLYQALGIPSDLAARASRLTATVEVSDADGRLTCKTTMGNKTFSTVFTDGTQLEANGPEQYVLSFDPAKQTMAAGPHSLSYTLTSAGLEVHVVSAGLDCKVVFQSGVAAPSAAGEVTAFCSALYRFNRCVQRHSLIGGLWYHPEGLVGLFPPFSPGHSWESANPFCGESTLYTRTWSVSGFSSCFSPLEPCVPSMPPPAEVNTPVVLDALPSEIMEPAQPPASEPAAPPSDSVDNSFSPTSSGAPIAPPAPALPVTHLSGPRRRLLHTYPDGSKVYAGSLFESECTWLVNASNPGHRPGGGLCHAFYQRFPESFDPAEFIMSDGFAAYTLTPRPIIHAVAPDYRVEHNPKRLEAAYRETCSRRGTAAYPLLGVGIYRVPVGLSFDAWERNHRPGDELYLTEPAIAWFEANRPTLPALTITEDTARTANLALELDAATEVGRACVGCRVEPGVIHYQFTAGVPGSGKSRSVQQGDVDVIVVPTRELRNSWRRRGFAAYTPHTAVRVTRGRRVVIDEAPSLPPHLLLLHMQRASSVHLLGDPNQIPAIDFEHAGLVPAIRPELVPTKWWHLTYRCPADVCELIRGAYPKIQTASRVLRSLFWEEPPVGQNLVFTQAAKAANPGAITVHEAQGATFTETTIIATADARGLIQSSRAHAIVALTRHTEKCVVVDAPGLLREVGISDAIVNNFFLSGGQIGQHRPSVIRRGTIDNNVDTLDAFPPSCQFSAYHQLAEELGHRPAPIAAVLPPCPELEQGLLYMPQELTTSDSVLTFELTDIVHCRMAAPSQRRAVLSTLVGRYGRRTKLYEAAHTDVRGSLNHFIPELGPINVTTCELYELVEAMVEKGQDGSAVLELDLCSRDVSRITFFQKDCNKFTTGETIAHGKVGQGISAWSKTFCALFGPWFRAIEKEILAALAPNVFYGDAYEDTVLAAAVAGAPGCKVFENDFSEFDSTQNNFSLGLECIIMEECGMPQWMIRLYHLVRSAWILQAPKESLRGFWKKHSGEPGTLLWNTVWNMAVIAHCYEFRDLKVAAFKGDDSVVLCSDYRQSRDAAVLIAGCGLKLKVDFRPIGLYAGVVVAPGLGTLPDVVRFAGRLSEKNWGPGPERAEQLRLAVCDFLRKLTNVAQVCVDVVSQVYGVSPGLVHNLIGMLQTIADGKAHFTETIKPVLDLTSSIIYRVE
What is the function of this protein?
RNA-directed RNA polymerase: Plays an essential role in the virus replication (By similarity).  Binds to the 3'-end of the genomic RNA to initiate viral replication (By similarity).
What are the official names of this protein?
Non-structural polyprotein pORF1.
What is the protein family that this protein belongs to?
Belongs to the hepevirus non-structural polyprotein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: FAD12_ACHDO
Sequence: MDLNEESAPSGVLFEEDVAEQEAKMANGGPKKGKKLEEPYRLEIVWFNVLWFVLLHAGALYGVYLIFASAKIYTTLYGFLLCELSLLSITAGVHRLWAHRAYKAKWPLRLTLMVLNLLAYQNSIYEWARDHRVHHKFSETNADPVNAKRGFFFSHVGWLLCRKHPEVRAKGGRIDLSDLERDPIVMFQKRHYYKLVPFVSFVIPTLIPMYFWGETLSNSWYVSTMFRYCLSLNLTWLVNSAAHMWGNKPYDKNINPVENLAVAIGSLGEGWHNFHHVFPWDYKTSELGNYSLNFTNAFIDLAVLLGLAYDLKTVPVSMIKTRVGRTGDGSHDVWGWGDKDLPKELADQTMIENRKTE
What is the function of this protein?
Catalyzes the formation of a Delta12 double bond, acting on monounsaturated fatty acyl subtrates like palmitoleoyl-CoA ((9Z)-hexadecenoyl-CoA) and oleoyl-CoA ((9Z)-octadecenoyl-CoA) with higher desaturation activity on (9Z)-octadecenoyl-CoA than (9Z)-hexadecenoyl-CoA.  Requires preexisting cis double bond at the Delta9 position of fatty acyls to be able to insert the Delta12 double bond.  Delta12-desaturation of (9Z)-octadecenoyl-CoA in insects produces (9Z,12Z)-octadecadienoyl-CoA (linoleoyl-CoA) which may be used to supply precursors of crucial mediators of immunity and reproduction and other essential functions (PubMed:19133076, PubMed:21300802).  Can also catalyze Delta9-desaturation on saturated fatty acyl substrates like palmitoyl-CoA (hexadecanoyl-CoA) but with lower efficiency (PubMed:21300802).
What are the official names of this protein?
Acyl-CoA Delta12-desaturase, AdD12Des, Delta-12/Delta9 desaturase, AdD12/9des.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YH93_SCHPO
Sequence: MSLLRYFIFFIGGCTLALASGVSYTEASVYMSGLSGNENEVPSISPSDSRLVFAHKLGVSRFHKLKSHSGARKIINEMLHSHSELSSFFYAEKSNTFLTIAGLAESELFDTLNPAFRISSCPSSNAFASLMCRYERQLDSLDNGKTTDIYLNDIGGVISIHDSTGVYSQITTTPYKSLEDYEQLFGEDKASMFDISVKQDRVFLSEIYALKILVEFLSSKSQQERSDTSIVIGQLVGLEALYEKYGKDSKIYQVARENMMTLLSMIKQVSSTYTFILLPPIDSSETSTRYHKRQVDMEAFGEEIEEVVASYEKNYNGRCYISEEACSKATNDCSGHGRCSKYGQLDSCYVCQCSNSVVSNAAGQNKTIRWAGESCSKQDISVEFQFFFWFTIIGFGLLIFSIMLLFSIGQEELANVLTSTATVIKKTT
What are the official names of this protein?
Uncharacterized endoplasmic reticulum membrane protein C1709.03.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NHAB_ECOLI
Sequence: MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKVREVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSLTGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLFYIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMGWIATL
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons (PubMed:1317851, PubMed:8093613, PubMed:8019504, PubMed:7929345).  Catalyzes the exchange of 3 H(+) per 2 Na(+) (PubMed:7929345).  Can also transport lithium (PubMed:8019504).  Essential for regulation of intracellular pH under alkaline conditions (PubMed:7822245).  Is necessary for growth on Na(+)/symport substrates such as glutamate and proline under conditions in which nhaA is not expressed, such as acidic pH and low Na(+) concentration (PubMed:8093613).
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELK_DANRE
Sequence: MVYVSNGQVLDSRSRSPWSLSFLTDFFWGAVEFIGLFFQTLVQPDLSKDGNNSASSRFSDGRGPPGFPGRRRMGRINHGAGPTPPPMGGGGUGR
What is the function of this protein?
Required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity).  Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins (By similarity).  Required for cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation (By similarity).  Required for palmitoylation (By similarity).
What are the official names of this protein?
Selenoprotein K, SelK.
What is the protein family that this protein belongs to?
Belongs to the selenoprotein K family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single- pass membrane protein. Note=Probably mainly localized in the ER.
Protein: DIS1A_DICDI
Sequence: MSTQGLVQLLANAQCHLRTSTNYNGVHTQFNSALNYKNNGTNTIDGSEAWCSSIVDTNQYIVAGCEVPRTFMCVALQGRGDADQWVTSYKIRYSLDNVSWFEYRNGAAVTGVTDRNTVVNHFFDTPIRARSIAIHPLTWNGHISLRCEFYTQPVQSSVTQVGADIYTGDNCALNTGSGKREVVVPVKFQFEFATLPKVALNFDQIDCTDATNQTRIGVQPRNITTKGFDCVFYTWNENKVYSLRADYIATALE
What is the function of this protein?
Galactose- and N-acetylgalactosamine-binding lectin.  May play a role in cell-substratum adhesion rather than in cell-cell adhesion.  May be necessary for the maintenance of normal elongate morphology during aggregation.
What are the official names of this protein?
Discoidin-1 subunit A, Discoidin-1 subunit alpha, Discoidin I chain A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQE_PSEU2
Sequence: MSDIAPVTNTPYIPPTPEVGLPLWLLAELTYRCPLQCPYCSNPLDFAKQGQELSTEQWFKVMQEAREMGAAQIGFSGGEPLVRQDLAELIAEARRLGFYTNLITSGIGLTEEKIIAFKEAGLDHIQISFQASDEQVNNMLAGSKKAFAQKLEMARAVKRHGYPMVLNFVTHRHNIDRIDKIIELCLALEADFVELATCQFYGWAHLNRLGLLPTKDQLVRAEAVTNEYRARLEAENHPCKLIFVTPDYYEERPKACMNGWGNIFLTVTPDGTALPCHGARQMPIQFPNVRDHSMQHIWYDSFGFNRFRGYDWMPEPCRSCDEKEKDFGGCRCQAFMLTGDAANADPVCSKSYHHGIITQARDESETATQTIEELAFRNDRNSRLIAKSS
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: CBID_PROM5
Sequence: MKKGFSLPLWVTGAAKSAVKKLTGLPFEDYELIKIPNDKNLIKIKVHSAGLIKDESHALGISFADSGLDLDVTQNLEIWTIAFLEKTYEKDNNSLDLINIIPGYGVGIDQKTSEICISKFAKEVLFENLLEILPAGYKLNLEIIFPNGKFLAERTSNQSFGIVQGLSIIGTSAETFSSASPDQLKNAKAQLEKIVSHDFYETIIFVIGENGLHLAKSSNIKFPIIKVGNWIGPLLVDAALKKIKRVILFGYHGKLIKLAGGIFHTHNHLADARIEILVYLAVKEEVPIEMIKKLSLASNVEDALLLLESSSPSLADKLWNKLSDTVEKRSSEYLKRYITTDMKVAAIIFDRQRKIRWSGDNGKDYISSFKGF
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: SP5G_ALKMQ
Sequence: MKVTDVRIRKVAAEGKMKAIVSVTFDEEFVVHDIKIIEGQNGLFIAMPSRKMGEGDFRDIAHPINSDTRSKIQDAIFAEYAIMNEEVQVQVQVTEEAL
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: ACP7_DANRE
Sequence: MAAAPPPPPPLLLLLLCVCAVFADVPIGTQPEQVHISYPGVQNSMLVTWSSANKTDSVVEYGLWGGKLFSHSATGNSSIFINEGAEYRVMYIHRVLLTDLRPAASYVYHCGSGAGWSELFFFTALNESVFFSPGFALFGDLGNENPQSLSRLQKETQIGTYDVILHIGDFAYDLYEDNGRIGDEFMKQIQSIAAYVPYMTCPGNHEWAFNFSQYRARFSMPGDTEGLWYSWNVGPAHIISFSTEVYFYYLEYGLDLLFRQYEWLRADLQEANRPENRAERPWIITMGHRPMYCSNDDDDDCTHFQSYVRLGRNDTKPPAPGLEELFYQYGVDLELWAHEHTYERLWPVYDYKVFNGSSEEPYVNPKAPVHIITGSAGCREKHDGFIPKPRDWSAFRSTDYGYTRLQLINNTHLYLEQVSDDQYGKVIDQMTLVKEKHGPDAWR
What are the official names of this protein?
Acid phosphatase type 7, Purple acid phosphatase long form.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPMI_ANTSP
Sequence: MNNKSISPIILMILDGWGHSTNAKGNAIHEANTPIIDKLWDNYPKTLLSASGEHVGLPHKQMGNSEVGHTTIGAGRIINQDLVKISKSIKNKEFFNNYQLHNIYKYSCEKNSKVHIVGLCSNGGVHSHINHLKALIQISKQYKVMTCLHLITDGRDTLPKQAKLFVKEIIDIIDENYNTEICTISGRYYSMDRDCRWSRTEKAYKAMVENSCNQNSSSDILSIIDKYYEQNISDEFLPPTKISMHNIVHNDSLIFFNFRPDRIRQLLHSFAKPNFKGFQRKTIKNLMLTTFTEYDSTLSIPTVFPNEPKKNFLGQIISNSGLKQLRLAETEKYAHVTYFFNGGIEEPFPGENRELIASPKVETYDLPPEMSAYQLTNSLIEAINKQLYQFIVINYANPDMIGHTGNMNATIEAIEIVDQCIEKVLHTIEDTNNILIITSDHGNADYMLTDENKPCTSHSINPVPFILINNRQKKQTNLHSHGSLADIAPTILDILNINIPNEMNGKSLIT
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: QUEC_PROM2
Sequence: MTLKNKSIVVLLSGGLDSSTVTGIAKKSEAKIFGLSFDYGQRHKKELYSASIIAKHFNIEEFKIIKLDLSLWGGSSLTDTQKNIPLEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEEIIKLAYSNHVPLEKTWSCYSGYSKPCGKCDSCRIRNDAYEKWLNNNNKK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: SYDP_SHELP
Sequence: MSSLPALDQFFTLYHQAYSDKLGESPRYFPLGEASPCVLECDQEKVDASPERSVQWQAVKRDSQGPFDNIEHALSITLHPSIQAFYGRYFAAPLMFESEFGEGELLQPWNQQDFEYLQQNLIGHLMMKQKLKQPATWFIGVLGEGDEMLVVENETGSVWIEIPGEQPHRQLAASLEDFIASLRPRVCPPQKPVEAPMPETDHPGIWQRLKTMWRHLIAKR
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: RL36_TRIEI
Sequence: MKVRASVKKICEKCRVIRRRGRVMVICVNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TRPB_AGRFC
Sequence: MNDAPTPNSFRAGPDEDGRFGIYGGRFVAETLMPLILDLQAEWDKAKSDPEFQAELKYLGTHYTGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCLGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVARQAPNVFRMKLLGAEVKPVTAGHGTLKDAMNEALRDWVTNVDDTYYLIGTAAGPHPYPEMVRDFQAVIGEEAKAQMLEAEGRLPDMIIAAVGGGSNAIGIFHPFLDDKNVRIVGVEAGGKGLSGEEHCASITAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPGIGPEHSWLNDIGRVEYVPIMDHEALDAFQMLTRLEGIIPALEPSHALAEVIKRAPKMGKDEIILMNLSGRGDKDVHTVSKFLGMDV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ANMK_BORA1
Sequence: MTQPINGPDNPGRCFIGLMSGTSMDGVDGVLLRLDGAPHLLASVSLDIPPSLRATLLALNSSGPDELHRAALAANELARLYAQACAQLRQAAPEARVRAIGAHGQTVRHRPDLGYTVQLNAPALLAELSGIDVVADFRSRDVAAGGQGAPLVPPFHDAMFGGRGAPRAVLNLGGIGNVTLLAPGQAPRGFDTGPANVLLDAWCHAHTGKHYDHNGNWAATGSVSKALLHHLLNSEPWFDLPAPKSTGRDLFGLGWLHKHLDSSGLRLSPQDVQATLVELTAQTVARAIASEPIQDLLVCGGGARNPAIMQALARALPCPVAPTDSEGVPGQWVEAMAFAWLAQAFIDRLPAGLPGVTGARGPRVLGALYPAA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ATGT_METJA
Sequence: MTFEIKHRDAMGRIGILNINGKKIETPTIMPVIHPNPKKQIVSMDLINKLADVIITNSYITYKTKHLREIAEEKGIHKLIGFDKVIVTDSGSFQLGVYGDVEVEPMEIIEFQERIGVDVGTILDIPTPPDVDRERAEKELEETLKRAKASIELKEERGFKLLLNGTVQGSTYLDLRQKSAKEMAKLGFDIYPIGAVVPLMEQYRYRDVAEIIINSKMYLPTNKPVHLFGCGHPMFFALAVALGCDLFDSAAYALYAKDDRYLTERGTLHLEEIKDLKAFPCSCPVCSSYTPKELASLNKKERERLLAEHNLYVTFEEINRIKQAIRDGSLWELVEERVRCHPKLLEAYRVVRKYIDYIEKFDPVTKKSAFFYTGIESMFRPEVLRHKKRLKRLRYEKVYITTVSSSIEKPYHEHLNVVETDVDILIKDPVFGFIPYYIDTVYPLSQHEIPELFDYEKEINKRFVDEFIDWLKKKIGEDNILDIMTYNYYINYFSANKKINADALRIRKMLQYQYGFDIIDDELMNKIKVVRSKTTGRLRQVLDENGEILFSVRSNDNLLIPSEKGAKLLWKKIPFPKYRVVVNKEAEEFAREGRNVFAKFVIDCDEELRPYEEVLVVNEDDELLAYGTTILNGIELREFNYGLAVKVRGGLKINK
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.  Can also utilize guanine as substrate.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: HRI1_YEAS8
Sequence: MPALLKRLLFQVGPHPNERTFTLSSVSTDGHYISLRPFVKPSGDELSFPFEWAFAGTNETVKVNDQGNGVVTQDFNFWLDTNVYLNVPNTHRGEVNTTWKNWDSGCVEETGAVYPFGADKESVSFRELWQPVDPSREDLVIVSPNNEKFSSNARSIVLKVTDEAYDGLVIVIGRWIQGFLSQKNNNTIEGLNFIRLLEKDSGKSEFLLSYGKEVNKIPQSYENLKKGSTVTSNGLNWEVIEYHA
What are the official names of this protein?
Protein HRI1, HRR25-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the HRI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RLP50_ARATH
Sequence: MITIIWSLCLIFCLSNSILVIAKDLCLPDQRDALLEFKNEFSIPSPDSDLMLILQTTAKWRNNTDCCSWGGISCDPKTGVVVELDLGNSDLNGRLRSNSSLFRLQHLQSLDLSYNDLSCTLPDSSGNFKYLRVLNLLGCNLFGEIPTSLRSLSYLTDLDLSYNDDLTGEILDSMGNLKHLRVLSLTSCKFTGKIPSSLGNLTYLTDLDLSWNYFTGELPDSMGNLKSLRVLNLHRCNFFGKIPTSLGSLSNLTDLDISKNEFTSEGPDSMSSLNRLTDFQLMLLNLSSLTNVDLSSNQFKAMLPSNMSSLSKLEAFDISGNSFSGTIPSSLFMLPSLIKLDLGTNDFSGPLKIGNISSPSNLQELYIGENNINGPIPRSILKLVGLSALSLSFWDTGGIVDFSIFLQLKSLRSLDLSGINLNISSSHHLPSHMMHLILSSCNISQFPKFLENQTSLYHLDISANQIEGQVPEWLWRLPTLRYVNIAQNAFSGELTMLPNPIYSFIASDNKFSGEIPRAVCEIGTLVLSNNNFSGSIPPCFEISNKTLSILHLRNNSLSGVIPEESLHGYLRSLDVGSNRLSGQFPKSLINCSYLQFLNVEENRINDTFPSWLKSLPNLQLLVLRSNEFHGPIFSPGDSLSFSKLRFFDISENRFSGVLPSDYFVGWSVMSSFVDIIDNTPGFTVVGDDQESFHKSVVLTIKGLNMELVGSGFEIYKTIDVSGNRLEGDIPESIGILKELIVLNMSNNAFTGHIPPSLSNLSNLQSLDLSQNRLSGSIPGELGELTFLARMNFSYNMLEGPIPQGTQIQSQNSSSFAENPGLCGAPLQKKCGGEEEEDKEKEEKDKGLSWVAAAIGYVPGLFCGLAIGHILTSYKRDWFMRIFSCFSSPLKK
What are the official names of this protein?
Receptor-like protein 50, AtRLP50.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GLYA_ECO8A
Sequence: MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEKQAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDSINDEAVIERIKGKVLDICARYPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_THET2
Sequence: MGNKAERHRAIQEIVRREEIGTQKELVERLRQLGFEVTQATVSRDIAELGLARIALGKGRHRYVLPAADLPENAYEELKRQFGLFVRDVDRGGNLLVVKTAEGHASGIAYLLDRLRRDEIVGTLAGDDTILVVARTEEAAQALEDEFAGLLVEGRALRRALSGS
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP16_BPLP2
Sequence: MLEANVYDNFNPNYYNISDFSMPNGKKEKRGLPIPKARCQVINYELWETGYLYTSSATLTVSVEVGDIVQILFPEVVPIEEALGKKKKLNLDMVYLVTDVDESNKATLKNYFWAMIESLDVPNAITKTTNFAIIDYLIDPNKNNLMSYGYFFNSSIFAGKATINRKAETSSAHDVAKRIFSKVQFQPTTTIQHAPSETDPRNLLFINFASRNWNRKRITTRVDIKQSVTMDTETIVERSAYNFAVVFVKNKATDDYTDPPKMYIAKNNGDVIDYSTYHGDGTDLPDVRTAKTLFYDRDDHGNPPELSTIKVEISPSTIVTRLIFNQNELLPLYVNDLVDIWYEGKLYSGYIADRVKTEFNDRLIFVESGDKPNVI
What is the function of this protein?
Forms a dome thereby closing the central channel at the end of the baseplate.  Changes its conformation upon activation by calcium allowing the channel to open at the bottom of the baseplate for DNA ejection.
What are the official names of this protein?
Baseplate protein gp16, Gene product 16, Gp16, Tail-associated lysine-like protein.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus baseplate protein gp16 family.
What are the subcellular locations of this protein?
Virion. Note=Part of the baseplate.
Protein: IME2_YEAST
Sequence: MVEKRSRQSSSSGSEFSVPPDVDNPPLSIPLKTLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSDFVNTNHITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPFFENTVASQVDARGNVTNTEQALIFAGINPVATNTKPIYFNSSTKLPAETESNDIDISNNDHDSHAMCSPTLNQEKLTLVEFLNEFVEEDNDDHSIPDVGTDSTISDSIDETELSKEIRNNLALCQLPDEEVLDHSLSNIRQLTNDIEIINKDEADNMEQLFFDLEIPEKDEFQRKQPFNEHADIDEDIVLPYVNNSNYTHTDRSHHRGDNVLGDASLGDSFNSMPDFTPRNFLIPTLKKSREKFEPHLSNSNQHFGNVTF
What is the function of this protein?
Protein kinase which is essential for the initiation of meiosis and sporulation.
What are the official names of this protein?
Meiosis induction protein kinase IME2/SME1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: TRUB_EHRCJ
Sequence: MYGWVNLDKPCGMSSALAVNLVKRILNVKKAGHAGTLDPLASGVLPIAIGEATKVMPYAVDVIKSYLFTVQWGEQRTTDDAEGEIVDKSDMIPCVENIKKIIPDFIGLLKQVPPSFSAVHVNGVRAFELARSGQDVNLSSRFVDVLELKLLSFDVENNKADFYLSCRKGVYVRSIARDLGIKLGCLGYVTKLQRVRVGCFRKKNAITLEMLKTLYSTNCKSSYLLPLWYVLQDIKHLNNFFSELEIKKLKNGQNIELNNLYVIRNCDICYVSTGNVPVAICSIVNSVVRPVRIFNVRGLVF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: LEUC_BRUME
Sequence: MSAPRTLYDKIWDDHVVDQQEDGTCLLYIDRHLVHEVTSPQAFEGLHMAGRPVRHPEKTLAVVDHNVPTSPDRINGIQNEESRIQVEALARNAADFGVEYYSERDKRQGIVHIVGPEQGFTLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKAKNMLVRVDGKLPAGVTAKDIVLAIIGEIGTAGGTGYVIEYAGEAIRSLSMEGRMTICNMSIEGGARAGLIAPDETTFEYIKGRPRAPQGETLEQAINYWKTLHSDEGAHFDKIVTLDAGSLPPIVSWGSSPEDVVSVTGVVPNPDDIADETKRASKWRALDYMGLKPGTKITDIAVDRVFIGSCTNGRIEDLRAAAKVVEGKKVAPTVNAMIVPGSGLVKEQAEAEGLHKIFIEAGFDWREPGCSMCLAMNDDRLKPGERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGHFVDIRAWK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: THII_SACD2
Sequence: MRFVVRLFPEISIKSAPVRKRWTKMLTDNLRLMAKRIHPTARVNKEWDRIEVTAKVDDPVVEGQLIDMLARTPGIANFSHVQTHPFESLHDIYELVQASWGDQLKGKTFCVRVKRTGNHDFTSTEVERYVGGGLNQNNPTGGVKLKDPDVSIGLEVKDDQVYLVTKKYQGLGGFPMGTQESVLSLISGGYDSTVASFQMIKRGLRTHYCFFNLGGREHELAVKEIAFFLWNRFGSTHRVRFISVPFEGVVGEILQKVGPSNMGVVLKRMMLRAGERIAERGGIEAMVTGEAVAQVSSQTIPNLSVIDSVTDMMVLRPLIVMDKRDIIDISRKIGAEEFSAAVPEYCGVISVKPSAKVNRAKLEAEEEKFDFSILEHALENAVVQSIDEVMDDAQELAEVELVSELPVSAKVIDIRHHTEQELRPLTVEGREVLEIPFYQLSTAYAELDKAVNYYLFCDKGVMSGLHARHLLDAGYTNVGVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.