PharMolix/UniProtQA huggingface dataset:
Protein: RLME_HAES1
Sequence: MGKKKRSASSSRWLNEHFKDPFVQKAHKQKLRSRAYFKLDEIQQSDRLFKHGMTVVDLGAAPGGWSQYAIRQIGDLGRVIACDILEMDPIVGVDFLQGDFRDENVLQALLERVGEKKVDVVMSDMAPNFSGMPAVDIPRAMYLVELALDMCKQVLATNGCFVVKVFQGEGFDDYLKEIRSLFNTVKVRKPEASRGRSREVYIVAMGYMG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD1_METMP
Sequence: MKFRQKHEDFIVNEILEYELNDYGNYFLYKLQKNGIENLKAISYLSKNFEVPTKEIGYCGLKDRHAITTQYVSIPKEYGKLSLDEDNLKLEYVGTIEKPLKIGRLYGNRFEIIARAVDKDEFLKIADNIRNLSSGAPNYYDDQRFGSVFNGKFIAKEILKGNYEEVVKILLTSYTKSEKKQLKDLKRFIAKNWGNWDECLEYIDKKQIRSKMFRNMVKSLTYENDFKKAFKYVDNRLKELFISAYQSYLWNECLKEFLKEVIPKENRIYVDYSCGTFLFYENIEEELFDKLKEMDFPTIVSDVEYTDPEKRIIKAILKKERIKISDFEKLDFGKLKYTKRPIISIPEDVNTGKFKSDELNSKKYKIDLEFSLKKGSYATIILKRVFNIL
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D 1, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D 1, tRNA-uridine isomerase D 1.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: MNME_NEIG2
Sequence: MSDNVPTIAAVATAPGRGGVGVIRISGKNLLPMAQALCGKTPEPRVATYADFTDADGQAIDSGLLLFFAAPASFTGEDVIELQGHGGPVVMEMLLNRCLELGARLAEPGEFTKRAFLNDKLDLAQAEGVADLIDASGRSAARLALRSLKGDFSRRIHGLVEGLITLRMLVEAALDFPEEDIDFLEAADARGKLDGLRRAVDDVLANAQQGAILREGLNVVLVGAPNVGKSSLLNALAGDEVAIVTDIAGTTRDAVRERILIDGVPVHIVDTAGLRETDDVVERIGIERSRKAVSEADVALVLVDPREGLNEKTRMILDTLPSDLKRIEIHSKSDLHAHAAGGFGTGAETVIALSAKTGDGLDALKRTLLCEAGWQGESEGLFLARTRHVNALKAAQEELSLAALCGNHQIELFAEHLRLAQVACGEITGEFTADDLLGVIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFD1_CAEBR
Sequence: MADEEISKAFRDLQFKTNETRMRIVQGEQNKKVNHQKMRISESTKRNLIGLNEDLKYYRSVGRMFLLTDKASEIARHETEAKQSKDKIEAIDKQKEYLEKGLVEAESNLRELIQSRR
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.  Has a role in gonadogenesis (By similarity).
What are the official names of this protein?
Probable prefoldin subunit 1.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_PETMO
Sequence: MEINTELIKKLKKLSNIELSPSEEERIKKDLNALLEYQKILDKIDVEGIEEMVSPIEFSTSILRKDEVESFESRKKIINNFPENKDGFLAVPGIHVNEEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: COLL2_HUMAN
Sequence: MAAALALVAGVLSGAVLPLWSALPQYKKKITDRCFHHSECYSGCCLMDLDSGGAFCAPRARITMICLPQTKGATNIICPCRMGLTCISKDLMCSRRCHMI
What are the official names of this protein?
Colipase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the colipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBP15_YEAST
Sequence: MSSEDELGSIGTVFPGSPIDKSIGSILPQFDEEVETLLEDSFTWNIPDWNELTNPKYNSPRFRIGDFEWDILLFPQGNHNKGVAVYLEPHPEEKLDETTGEMVPVDPDWYCCAQFAIGISRPGNGDTINLINKSHHRFNALDTDWGFANLIDLNNLKHPSKGRPLSFLNEGTLNITAYVRILKDPTGVLWHNFLNYDSKKVTGYVGFRNQGATCYLNSLLQSYFFTKYFRKLVYEIPTEHESPNNSVPLALQRAFYQLQVSDIPLDTLELTRSFGWDTAESFTQHDVQELNRILMDRLENNMKGTPVEGKLNEIFVGKMKSYIKCINVDYESARVEDFWDLQLNVKNFKNLQESFDNYIEMELMNGENQYAAQDYGLQDAQKGVIFESFPPVLHLQLKRFEYDFNYDQMVKVNDKYEFPETIDLSPFVDKDVLKKTLDSENKDKNPYVYNLHGVLVHSGDISTGHYYTLIKPGVEDQWYRFDDERVWRVTKKQVFQENFGCDRLPDEKVRTMTRGEYQNYIIQRHTSAYMLVYIRQEQEEDLLRPVLESDVPKHVITRVREEIKERETKEKEIREAHLYVTLRLHSIKEFIHYEGFDYFAHDGFRLFAEELNDSGLQQINLKVLRTTKLSDIFASIKETMNIPQERDVKYWKMDYRRNSTLRLTQPINFESVNITLQEALKKEKKRTMQTQYGEEGVASTEEDDKALLETVSFLDLFIEEPYLELQFLNKLKEASLISKAQLDDELISTIRTNLPELTKGGIEPVFATDNKSNLLFVKSYDPHTQKLLGFGHFAVNQLQQLSDISAIIEDSISSNEKLTFYEEVQPGTINEIYMKETIYDADIDTGDIVSFEVPGAVLPDTFPVYATIKDFYSYLRYRVKLKFSKFDGSSEEYGVSNEIPESFEFWISAYAPYDDLARMVSKYAHVKPEYLKIIALYSNGRFVLKSTSLLNDYLLKDFNCDQIPPFAFEVLSVPLKELERLRPIKLYWLKNSYIHYQCFEFEVANDYTESQFLEKVQHKIGFTDEEKENILLWTNTNFQFQGLLSDQNTFKDVSKHSLLFGRILPEESKLFKELNRLENVQTSSLEDFMDDENATDRPMDDEQDLGMAIEHSEDMKGRIVVVQQYFKDLENRHGISFLFNLIPDETFPKTKDRLHAKFGLGQKEFSKIKLSIGYSTEEGTVFRSLQGFSDEELDKVILYDIMSNLDYIYMDHPDRLRSHSSYDRPMIIKN
What is the function of this protein?
Deubiquitinase involved in peroxisome import by mediating deubiquitination of the peroxisomal import receptor PEX5 (PubMed:21665945).  Catalyzes deubiquitination of both monoubiquitiated and polyubiquitinated forms of PEX5 following its retrotranslocation into the cytosol, resetting PEX5 for a subsequent import cycle (PubMed:21665945).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 15, Deubiquitinating enzyme 15, Ubiquitin thioesterase 15, Ubiquitin-specific-processing protease 15.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: HOLA_BUCAP
Sequence: MKIIYPEELKQKLIKKLNYFYILLGEDSILLSKAEQLIFYFAKDKKFIEKNTINIEKSTDWNKVINFHKSKNLFFKKTILIINFTIKKLNLSLVKNINKIPLFKNKDILTVIKLNALSSLIKKSTILKILILESEIIYCSTPYEWAFKKWLQYEIKTRNLKITQESFLLLHKYYEGNTLCLNQILDILSITWPNENIKIEKIKKIINQFSIFSPVNWINAIFNKNKKKAIYILDSFFKQKYNPLILIRTLQKDLLILLNMKREKKLNINFFLKKNNISLNRSKFFANALYYIDFNNFLKIIRILLQIEIKIKKEYNNSVWIQLKTLTLLLSSPMKYTP
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA (By similarity).
What are the official names of this protein?
DNA polymerase III subunit delta.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase HolA subunit family.
Protein: RECF_BACC4
Sequence: MFISEIQLKNYRNYEKLELSFEDKVNVIIGENAQGKTNLMEAIYVLAMAKSHRTSNDRELIRWDEDFGQIKGKLQKRNSSLSLELNISKKGKKAKLNQLEQQKLSQYIGVMNVVMFAPEDLNLVKGSPQVRRRFLDMELGQIAPVYLYELSQYQKVLTQRNHLLKKMQGNSKNEETMLDVFTLQLIEHGAKILQKRFEFLHLLQEWAAPIHRGISRGLEELEIVYKPSVDVSESMDLSKIKEVYYESFQSVKQREIFRGTTLIGPHRDDLQFFVNSKNVQVFGSQGQQRTTALSLKLAEIELIYSEVKEYPILLLDDVLSELDDYRQSHLLNTIQGKVQTFVTTTSVDGIEHETLKEAKTIHVTNGTVDCEIDRE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_ECOUT
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MUTX_ALKPO
Sequence: MRNFGIILAHTYKNRLMSKAFLISTVITLAFMLVLTNMDPYVNMLRGTSEAFSAAVAGADSIQVSPFDEPIQPSTSFSRRIARNTSLILMEESHLAATQDASGGAWYVEHLTDEIIVCKFKVILILNSVREYTDVIADSIFKLSRGH
What are the official names of this protein?
Methylmalonyl-CoA mutase homolog.
What is the protein family that this protein belongs to?
To methylmalonyl-CoA mutase.
Protein: GLGX_ECOL6
Sequence: MTQLAIGKPTPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNASIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGVFAGRFAASSDVFKRNDRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGTLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALMENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: Y4BB_SINFN
Sequence: MLPRSCKDFYETLRTAVLCGQACAKDMGAIVFHGLWQGLAVLIAQPPPPTHRRLESRPTASVAVHDRQLVHMLANMVLAAETRGNHVY
What are the official names of this protein?
Uncharacterized protein y4bB/y4pI.
What is the protein family that this protein belongs to?
To Rhizobium NGR234A y4oL.
Protein: PPID_RHIO9
Sequence: MSNPRVYFDITIGNKPEGRIVFELFKDIVPKTAENFRALCTGEKGEGKSGKPLSYQGSLFHRIIKNFMIQGGDFTAGNGTGGESIYGEKFEDENFVLKHEKPFLLSMANAGPGTNGSQFFITTVPTPHLDGKHVVFGKVLKGKAVVRALENLETVSDRPVEDAVIAKCGELAEGEDDGIRASEDGDVYEEYPDDHEGPKEPNDVLQIATHLKDIGNTYFKKGDHANAAKKYLKAIRYLNEKPAFDENDPKELEGKFAAIKIPCYLNRSMCALKLGEYSECVKVTTTVLEYDSKYLKPTDITKAYFRRGSAKMNTRDFEGAIEDFEKAHEKDPEDAGIKKELANAKAKLAAKKQKEKSAYAKMFA
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase D, PPIase D, Cyclophilin D, Rotamase D.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_PSEPG
Sequence: MTQDQLKQAVAQAAVDFILPKLDEKSVVGVGTGSTANFFIDALAQHKTAFDGAVASSEATAQRLKGHGIPVYELNSVSELEFYVDGADESDAHLNLIKGGGAALTREKIVAAVAKTFICIADGSKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVYREGVVTDNGNVILDVHNLQITNPVELEAQINAIVGVVTNGLFAARPADLLLLGTSEGVKSLKAE
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: OCA5_ASHGO
Sequence: MALQRNSKQNQQQWYRELVNKVIQLLQQNDHDSLALIARNCGVPPQLRHLVWPVLLKYHPFVISPSILSNTLIFDKTEDKWVYECENRARRDVEQAVMHDLQKFFVNKRSDQHMPLPDIEQHMRFLRDTIMRFLDKWERVFKYEVALAWIAIGLAEWVPIDGWGESAPGGGGVCSEDMALPKGRSTDVPVLQGKRHHITIRSLYKEYPLPRELSSRLTKRCFNFYDTFERLVLVILHCPDVTRTKMKVANGRNYPFISGGDVLFQTQLFFKIFQMTLPELYQPFTDEESLQSSRKADWIYWWFKACGAKVMHKQDRAHLWDVLLGWRPHPSTLNFYLDYNNKSFAHLYNTKLNLDPQFFHKVCKHGNDHFWFPDLDTLPLGSPGLETDCQVVNELIRHNSYESKDTGAPGTPSKTSQAGNNYRSPIRPSQKHQKDIPFSLIDPHVQLIFIYIAILQQNEFKLLEFEEAEITEFLTKVPLLSKTDDYSYKRLYDEESTSLSSTDTEDSQNSSSRPSTSSHMMIEVGNDDKIANTFDDLSQLAGDIWRKWMWFEFEESQDSV
What are the official names of this protein?
Oxidant-induced cell-cycle arrest protein 5.
What is the protein family that this protein belongs to?
Belongs to the OCA5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_DEIRA
Sequence: MLAGRDFLSNLDMTSAELRAVMDTAHSMKAGEWRAVKPLSGLSLALVFEKASLRTRTTFDVGMYQLGGHAITLSNTEIGLGTRERVSDVARNLERWVDGVMGRVYLQQTLVELAQHARIPVINGLSDMLHPAQLLADYQTIEEEFGQDLRGKRVVYIGDGNNLANSHIHMGILTGTDVTVVTPVGYEPNAGVLMDAVKAGVEVHLTNDLDAIQGADVLYTDVWISMGQEAEADIRRRAFRGYQVTPEMLETISPDGIFLHCLPAHYGEETVPEATEHPKSRVFDQAENRLHAQKALLYHVLGDMKPRW
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_POLFR
Sequence: MTNIRKTHPLIKIINHSFIDLPTPSNISAWWNLGSLLGLCLAIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNVGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFVLPFIIAALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGVLLLILALMTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPLLHLSKQRSMMFRPLSQCMFWILVADLFTLTWIGGQPVEHPFIIIGQLASILYFTIILTILPAASLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATG3_BOTF1
Sequence: MNFLHSTLDRLREFTPVSNTSTFRTNGQITPEEFVAAGDYLVFKFPTWSWADASPTSKRANYLPAGKQFLVTRGVPCHRRLDDDFAGDAGHDETVVRDGEDFRGDGPHSPGDDEDGWLRTGGLAASQEARVRDVRTVDESGEMGEREDDEDDIPDMEDDDDDDEAIIRDPKADNASSSRRTYTIYIAYTPYYRTPRLYLSGYLSSSQPLPPHLMMEDIVGDYKDKTVTLEDFPYFSNNIKMASIHPCKHASVMKTLLDRADAALKLRREKQRQGKAVPGSKDTGMEGLVDDFEKTKIGDKKAVLEGLKAGGNGNDEWEVLQHDQDFANEEEEVAIRVDQYLVVFLKFMASVTPGIEHDFTMGV
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (PubMed:29417220).  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity).  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8.  The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE) (By similarity).  This step is required for the membrane association of atg8.  The formation of the atg8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt) (By similarity).  The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).  Required for normal mycelial growth and conidiogenesis, and regulates sclerotial formation (PubMed:29417220).  Plays an essential role in pathogenesis (PubMed:29417220).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme atg3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLTK_ECO57
Sequence: MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVMRLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKRRTA
What is the function of this protein?
Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutamate/aspartate import permease protein GltK.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACTP_SHISS
Sequence: MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKLVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSITVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TORD_ACTP7
Sequence: MAHSQLLSSEERLFCYRWFHSLLAKELSEPQLQALQAGQFASFFALLAELGFQPQVTDLQNELAKLTAYDSPRLELAADFAQCFLLEGKLSALPYASYYLDERDLSENLAVMDQWLTKFQLKINRLHNEPSDHLCIYLEVLIKLIETEQPVQVQQQFIRQQLLGWLPQWAEKTAQIHSSTAFYQIISNLLLGFLQQDIA
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_BIFLS
Sequence: MSIASNSTVIILGSTGSIGTQGLDVIARHPERFTVTGLAAGGAHIELLAQQAAQFHVSEVAVFDETKIPALQAALAQAGAQGVRVTGGPDSVIAMAGSGANVVLNGITGSIGLEPSIAALKAGSQLALANKESVVAGGHLLFSAQVRENQINPVDSEHSAIWQSLRSGTHAEVAKLVVTASGGPFRGWKRADMENITPEQALHHPTWNMGPVVTINSSTLMNKGLEVIEASRLFDVPPERIDVTVHPQSIVHSMVEFVDGATICQASPPDMRLPIALGLSAPDRMANVAAACDWTKAATWTFEPLDDEAFPAVQLARHCLAASEKHTAVLNAANEQAVHAFLEHRLPYLGIVDTVKAVLDQMDAELRGNPLFTDVEEMNQLELEARRRADDLINKQ
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: NUDL_SALSV
Sequence: MDTSRLTLDHFLSRFQLLRPQMTHETLNQRQAAVLIPVVRRPQPGLLLTQRAIHLRKHAGQVAFPGGAVDSTDASLIAAALREAQEEVAIPPQAVEVIGVLPPVDSVTGFQVTPVVGIIPPNLPWRASEDEVSAVFEMPLAQALQLGRYHPLDVYRRGNSHRVWLSWYEHYFVWGMTANILRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: ARNE_ECODH
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DIAA_ECOSM
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: HSLU_AQUAE
Sequence: MTTKSLSELLEELTPKRVVEELNKYVVGQEEAKKAVAIALRNRWRRQKLPENLRNEVIPKNILMIGPTGVGKTEIARRLANLIKAPFVKVEATKYTEIGYVGRDVESMVRELVEVSFQMVKQEKMKEVRERARRLAEERLLDYLVPHQFTSFGIRESRDAGKREELRQKLRKGELDDRIVEIEVKEKTVPMVGIAGPPGLEELENQIKEMLSGLIPSKRRRKVKVKEALQILEQEEAEKLIDMEEVAREAIYRAENFGIIFIDEIDKIAVKTPGAGPGVSREGVQRDLLPILEGTTVNTKYGPVKTDHILFIGAGAFHMAKPSDLIPELQGRFPIRVELKPLTKEDFKRILVEPENALTKQYIELLKTENVYLEFTDDAIEEIARIAEEINTKTENIGARRLHTVMEKLLEDISFNAPEMAGQTIIIDAKFVKAKLENLVKDEELSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_ALBFT
Sequence: MSETNPNQTKPPATGYQSTEEMVAAQGAYESDALSRAQADLAELQAKSAELADQYLRAKAEADNARRRAEDEISKARKFAVEAFAESLLPVADSLEAGLIIKDATIDHLREGTQATLRQLLAALERNKVIPINPQPGTTKFDPHQHQAISVVPSEFDANIVVTVLQKGYAIADRVLRPALVTVAAPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.