PharMolix/UniProtQA huggingface dataset:
Protein: ES1AB_PELRI
Sequence: GIFSKLAGKKLKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
What is the function of this protein?
Antimicrobial peptide (By similarity).  Stimulates insulin secretion by BRIN-BD11 cells in vitro (By similarity).  Shows hemolytic activity (By similarity).
What are the official names of this protein?
Esculentin-1a/b.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Esculentin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NCPP_THEKO
Sequence: MKVAVGSTNPAKVEAVREVFLGIYGDVEVVPIEVDSGVPDQPVGLEETVKGAINRAKQAIEKTDADFGVGIEAGLYRVPETITGYMDVQFCAVVDREGRITLGHGPGFEYPPGVIRRVFEEGVEVGIAMGELVNDPELKRKIGAIGVLTHGMLVRKELNKLAVLMALVPRLNPEWYGL
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Probable inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: TVP38_SCHPO
Sequence: MPAPVSSIKIIALAAIGILIVVFAILLAVFHNDLLAIAMPIAERIAKLPMSFLIALVLIAASSIPPLLGQDPLALLIGAVWGLNVGFWTVVCGIFIGETIAFMAYRYFLEQKAQEFREHHEEHYGTFVKIVEEGSYPLIWLIRLSFLPTHFTTVFFATLPELSYIGWAIAFWLSCFKYLVPVYAGYCIVHNKSSAANIVGIVLSIVVTLGTLAFLIVRYKAIKNSTLEDSTNSTSDVLNHLESQPTDSIDLRHLEQTSEQNETDNSERKHLLSHQH
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking and spindle migration.
What are the official names of this protein?
Golgi apparatus membrane protein tvp38.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RIMK_ECOLI
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Polyglutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: YBEY_MESHJ
Sequence: MKAKINFLNQSRIKFKYLKLFRKIFKLLVEKEQITGEISLDLMLITQRKAQKLAIKFKNINYIPDVLSFPSNLIIAKKNFRLHFLGEIFMTPAKIIKQANEYGHSEEREFSYLFVHSIYHLLGFDHQDEKTNKLMDEKVENILINLGINR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_CHLPN
Sequence: MDLAVELKEGILLVDKPQGRTSFSLIRALTKLIGVKKIGHAGTLDPFATGVMVMLIGRKFTRLSDILLFEDKEYEAIAHLGTTTDSYDCDGKVVGRSKKIPSLEEVLSAAEYFQGEIQQLPPMFSAKKVQGKKLYEYARKGLSIERHHSTVQVHLQITKYEYPLLHFVVSCSKGTYIRSIAHELGTMLGCGAYLEQLRRLRSGRFSIDECIDGNLLDHPDFDISPYLRDAHGNSL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: SF3B6_DROME
Sequence: MNKRNHIRLPPEVNRLLYVRNLPYKITSDEMYDIFGKFGAIRQIRVGNTPETRGTAFVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYQSNKAFKRVDMDKKQEELNNIKAKYNLKTPEAP
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (Probable).  SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (By similarity).  Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing (By similarity).  Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively (By similarity).
What are the official names of this protein?
Splicing factor 3B subunit 6, Pre-mRNA branch site p14-like protein.
What is the protein family that this protein belongs to?
Belongs to the SF3B6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS10_PSEA7
Sequence: MQNQQIRIRLKAFDHRLIDQSTQEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRVLDIVQPTDKTVDALMKLDLAAGVEVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PDXH_MARMM
Sequence: MSDDKLIPATPDADAYAKTADANAAEIFDRDEPFALFADWLTEAKKKEPNDANAMALATADASGLPDVRMVLLKDVDADGFVFYTNLESGKGGQLADNPQAALCFHWKSLRRQVRVRGAVEPVSAGEADAYFASRARDSRIGAWASKQSRPLESRFALEKSVAREAARFGLGEVPRPPHWSGFRIRPLSLEFWRDRPFRLHDRMFFDRPDLGSTWTVTRLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: IF12_CUPPJ
Sequence: MAKEELVEFGGKVSEVLPDNRFRVTLENGFEVWAYSSGRLKRNRIRILAGDRVTLEMSPYDLTKGRINYRHKF
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPHB3_CHICK
Sequence: GVSSRARRPPGSSRSSRRGVTSELAWTTHPETGWEEVSGYDEAMNPIRTYQVCNVREANQNNWLRTKFIQRQDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYESDTDSASANSPFWMENPYIKVDTIAPDESFSKLESGRVNTKVRSFGPLSKNGFYLAFQDLGACMSLISVRAFYKKCSNTIAGFAIFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCAAGYEPAMKDTQCQACGPGTFKSKQGEGPCSPCPPNSRTTAGAATVCICRSGFFRADADPADSACTSVPSAPRSVISNVNETSLVLEWSEPQDAGGRDDLLYNVICKKCSVERRLCSRCDDNVEFVPRQLGLTGLTERRIYISKVMAHPQYTFEIQAVNGISSKSPYPPHFASVNITTNQAAPSAVPTMHLHSSTGNSMTLSWTPPERPNGIILDYEIKYSEKQGQGDGIANTVTSQKNSVRLDGLKANARYMVQVRARTVAGYGRYSLPTEFQTTAEDGSTSKTFQELPLIVGSATAGLLFVIVVVIIAIVCFRKGMVTEQLLSSPLGRKQRNSTDPEYTEKLQQYVTPGMKVYIDPFTYEDPNEAVREFAKEIDISCVKIEEVIGAGEFGEVCRGRLKLPGRREIFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLEGVVTKSRPVMIITEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPADPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFAQIVNTLDKLIRNAASLKVIASVQSGVSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKENFVNAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Generally has an overlapping and redundant function with EPHB2.  Like EPHB2, functions in axon guidance during development.  In addition to its role in axon guidance also plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses.  May control other aspects of development through regulation of cell migration and positioning (By similarity).
What are the official names of this protein?
Ephrin type-B receptor 3, EPH-like kinase 10, EK10, cEK10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite.
Protein: RS12_STRP8
Sequence: MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SEC7C_SCHPO
Sequence: MTFRIPSSQESSNKSEKDTTVNSPNASSFSSFFKKSSQTYLSKRSEKLNEHNSKLKSSGSFTSNSQTDLSNSPSSKKKNIFYPIARAKHSFYFNHNWSSDLQQANSPVASYSSQSVSNDSNFPKDVTSPISTDLSGSNPSLKSPSSINSAKLRASRSFFRFPKWSRKSWNPDVNSTTSSPSEVGSLDKAGGPLNQQNENLSAESDNTILQNGTRKSSVKMSDLGKRIASLPVVKRPPIQFSISSDYIKPVDKSDQTSNVPSPSSSVGSLRLYRSPSIPNDVEQPQPQSSRSRPRSSTIPTQRTLERLRENRSSIFSFRTLRRDDDECVAQTIENSALFSDIKPNPTKFLSSVPELTADDTAESYLSKLRETVPYSRMIPVLAEKDHVTLNKALHLCMSGMEFENRPLDFCLRLFLLKSHLPKETQQIDRVINAFSKRYFECNPGMFSSQDQCYILVFSLMMLHTDVFNSNNKHKMTKQEFINLCDIDELAPEIMEYYYDNITFTPFVNLDDELLLIEKEKNEKYNFTSRKRLGLSPYTFTLENQLNISRPEISLSYDGKFISPGIKDIASLLNVRKLISSPAIIQLVSKRSHPMAFSNHFIGLPDNADPGLVDFSISMLGILPRCEKKRRSVGHNSYKEHLVLLTASRILFFRNLVWAKDLMAQKKAYERRYKNFTTTSSSFDTLQGIDTEAMEYEFPKIPPLVFTPPLEEFSPDTSYSLVNAFAYCDRDKKNVRNCSFTVIFRDGSEETLCAPTEESMIEWVAKINYISTLRTAGLRMPVSDSYHPKRDFSCYPKYMEEELAAIEAQMKQDMEIARARTIKTRIDQLETSITEFNKKLMVLQRNAKNLSTCAPLQPKTRVVILQALKKVDAKAQSLYLEIRKMESQLQVLRFESDLDKCISLESSNDIDDRPSSTSPSTLKNPSINSINRQTHDVEKESSDRDVPHLLDPDNNFNLKGNPENPSSTFFTPEILSPKVYSDNVKDEPVEDIFGFEDTSESSPGKPSQLRLQIEAFDDELADTASLGSVTTCLDQWQTFSDDTDSGFALNLYSSEDFRTDPYKEHDEFSMNSLSKWHSATSDN
What is the function of this protein?
May play a role in protein transport.
What are the official names of this protein?
Protein transport protein sec73.
Protein: BETB_YERPB
Sequence: MSRYGLQKLYINGAYTDSTSGDTFDAVNPANGECIAQLQAANAQDVDKAVAAAKQGQPVWAAMTAMERSRILRRAVDILRDRNDELAAIETADTGKPLSETRSVDIVTGADVLEYYAGLIPALEGQQIPLRGSAFVYTRREPLGVVAGIGAWNYPLQIALWKSAPALAAGNAMIFKPSEVTSLTALKLAGIYTEAGLPAGVFNVLTGSGDQVGQMLTEHPGIAKVSFTGGIASGKKVMANAAGSTLKDVTMELGGKSPLIIFADADLDKAADIAMMANFYSSGQVCTNGTRVFVPQALQAAFEQKIVERVKRIHIGDPSDERTNFGPLVSFQHRDSVMRYIDSGKREGATLLIGGYSLTEGALAHGAYVAPTVFTHCRDDMQIVREEIFGPVMSILSYQSEEEVIRRANDTEYGLAAGVVTQDLNRAHRVIHQLQAGICWINTWGESAPEMPVGGYKHSGVGRENGISTLEHYTQIKSIQVELSSFNSVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: NP1_RHOPR
Sequence: MKSYTALLAVAILCLFAAVGVSGKCTKNALAQTGFNKDKYFNGDVWYVTDYLDLEPDDVPKRYCAALAAGTASGKLKEALYHYDPKTQDTFYDVSELQEESPGKYTANFKKVEKNGNVKVDVTSGNYYTFTVMYADDSSALIHTCLHKGNKDLGDLYAVLNRNKDTNAGDKVKGAVTAASLKFSDFISTKDNKCEYDNVSLKSLLTK
What is the function of this protein?
Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation.  Also binds tightly to histamine, which is released by the host to induce wound healing.
What are the official names of this protein?
Nitrophorin-1, NP1.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Nitrophorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PHOSP_RINDR
Sequence: MAEEQAYHVNKGLECIKALRARPLDPLVVEEALAAWVETSEGQTLDRMSSDEAEADHQDISKPCFPAAGPGKSSMSRCHDQGLRGSNSCDEELGAFIGDSSMHSTEVQHYHVYDHSGEKVEGVEDADSILVQSGADDGVEVWGGDEESENSDVDSGEPDPEGSAPADWGSSPISPATRASDVETVEGDEIQKLLEDQSRIRKMTKAGKTLVVPPIPSQERPTASEKPIKKGTDVKSTSSGTMAESSSTGGATRPALKSQWGPSGPNASAENALASASNVSPTQGSKTESGTTTSRISQSNIEPEDDYDDELFSDIQDIKTALAKLHDDQQIIITRLESLLSLKGEIDSIKKQISKQNISISTIEGHLSSFMIAIPGFGKDPNDPTADVDINPDLRPIIGRDSGRALAEVLKKPASERQSKDTGKLGIESKGLLKKEFQLKPIEKKSSSAIRFVPDGSVASRSVIRSIIKSSHLGEDRKDYLMSLLNDIQGSKDLAQFHQMLVKILKN
What is the function of this protein?
Essential component of the RNA polymerase and the nascent chain assembly complex.  Also required during RNA synthesis.
What are the official names of this protein?
Phosphoprotein, Protein P.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus P protein family.
Protein: RBL_TABHE
Sequence: SVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVXAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEADQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTWEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAAEGNAIIREASKWSLELAAACEVWKEIKFEFKAVDTLDPE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FABV_XANOM
Sequence: MIIHPKVRGFICTTTHPLGCERNVLEQIAATRARGVRNDGPKKVLVIGASSGYGLASRITAAFGFGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKAAGLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVVYSLASPVRKLPGSGEVKRSALKPIGQTYTATAIDTNKDTIIQASIEPASAQEIEETITVMGGQDWELWIDALEGAGVLADGARSVAFSYIGTEITWPIYWHGALGKAKVDLDRTAQRLNARLAKHGGGANVAVLKSVVTQASAAIPVMPLYISMVYKIMKEKGLHEGTIEQLDRLFRERLYRQDGQPAEVDEQNRLRLDDWELRDDVQDACKALWPQVTTENLFELTDYAGYKHEFLKLFGFGRTDVDYDADVATDVAFDCIELA
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  It can also use crotonyl-CoA.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR, Trans-2-enoyl-CoA reductase [NADH], TER.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: RHLB_SALTI
Sequence: MSKTHLTEQKFSDFALHPQVVEALEKKGFYNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIDDRKVNQPRALIMAPTRELAVQIHADAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPAAQRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIESYIGHSIPVSKYNPEALMNDLPKPLRLTRSRPGNGPRRAGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_PSEPF
Sequence: MATINQLVRQPRKRIVEKSDVPALQNCPQRRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTSGVKGRNQGRSKYGTKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: YQGF_BORA1
Sequence: MPEETLLAFDFGEKKIGVAIGNTLTCHARPLEIIFSERRDERFGRIQALLEAWRPQRVVVGLALATDGGDQPATLRCRRFANQLHGRFGVTVELVDERGSSMEAQEKLGSHAPDDAMAAAIILQRYLDRLA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRXB_BACCH
Sequence: MRRINERLDEILPKITDASFRENKGLGNEIGFYIFDYDPKYEMLVREHIVYMQERLKNDSSLHIREFDLYEVMLEILEEKGYLQKNIDMEQKKGSDFILNATRKALRLTSNNDLVVQYITDRVQPNDIVFLTGVGKVFPIIRSHTILNNLHKAVDNVPLVMFFPGTYDGLELVLFGEIKDDNYYRAFQLIDK
What is the function of this protein?
BREX systems (bacteriophage exclusion) provide immunity against bacteriophage.  Part of a type 1 BREX system.  This system allows phage adsorption but prevents phage DNA replication, without degradation of the phage DNA.  Methylation of bacterial DNA by PglX probably guides self/non-self discrimination.  When the brxA-brxB-brxC-pglX and pglZ-brxL operons are transformed into a susceptible B. subtilis strain (BEST7003) they confer resistance to bacteriophages SPbeta, SP16, Zeta, phi3T and SP02 and partial protection to phages SP01 and SP82G (these include lytic and temperate phage).  They do not protect against phages phi105, rho10 or rho14.  Additionally confers a very slight reduction in efficiency of plasmid transformation.
What are the official names of this protein?
BREX protein BrxB.
What is the protein family that this protein belongs to?
Belongs to the BrxB family.
Protein: DNAE2_PSEU2
Sequence: MTREYAELHCLSNFSFQRGASSARELFERALRHGYKALAITDECTLAGIVRAWQASKSTGLPLIVGSEMHIENGPKVVLLVENQAGYEALCKLITVARRRAGKGEYRVLREDFEPAPDGLLALWLPDLDGNAQACLAGGRWLRERFAERLWLGVGLHRGPDDEQRLADLLALAQSLGVPAVASGDVHMHARGRRALQDTMTAIRHHTTVAEAGHLLFANGERHLRPLDALSEHYPDWLLAESVRIARRCTFDLGDLKYEYPHELVPKGQTSTSWLRELTERGVRRRWPGGLTPATRAQVEKELALIAEKKFDSYFLTVHDIVEFARSQHILCQGRGSAANSAVCYALGITELNPEQSNLLFERFISRERNEPPDIDVDFEHDRREEVIQYIFRRYGRGRAALTAVASTYHGSGAMRDVAKVLGLPPEQINALAEAFSRWSDSLPSPERLREYGFDADTPILKRVLALTGELIGFPRHLSQHPGGFVISEHPLETLVPVENAAMADRTIIQWDKDDLDLVGLLKVDILALGMLSALRRTFDLVHLHRGQRWTLATLPGDDRKTYEMISRADTIGVFQIESRAQMAMLPRLRPEKFYDLVIEVAIVRPGPIQGDMVHPYLRRRNGEEDVTYPPKLESVFKRTLGVPLFQEQVMEVAILAADYTPGEADELRRAMAAWKRHGGLEPHRERLRTGMLKNGYEADFADRIFEQIKGFGSYGFPESHAASFALLTYASCWLKCHEPAAFTCALINSWPMGFYSPDQLLQDARRHHIEIRPVDVRYSDWDCSLEPLDHPDRTRNLAIRLGLRMVRSFREEDALRIEVARAKRPFVDATDLTLRAELDARAAEALADSGALRGLIGHRHRARWEVAGVEAQRPLFDDLPSEETQVTLPLPTVAEDLVADYTTLGTTLGPHPLALLRRQLAAKRFRSSQDLLHLENDRTLSVAGLVIGRQRPGTASGVTFVTLEDEFGMVNVVVWRDLAERQRKVLVGSQLLQVFGRLESKSGVRHLIAQRLYDLTPLLTGLDVRSRDFQ
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP_BCCV
Sequence: MGRLYLIVLGVLITATAGFPRSVHELKIECPHTVVLGQGYVTGSVELGFIALDQVTDLKIESSCSFDHHAAPTTTQNFTQLKWAKTASTTDTTNAAETTFESKSTEVHLKGVCTIPSNVLDGPSRPVTGRKTVVCYDLACNQTHCQPTVHLLAPIQTCMSVRSCMISLLASRIQVVYEKTYCVTGQLIEGLCFNPVPNLALTQPGHTYDTFTLPITCFLVAKKGANLKIAVELEKLTTKTGCAENALQAYYICFIGQHSEPLTVPMLEDYRSAEIFTRIMMNPKGEDHDMEQSSQGALRIVGPIKGKVPPTETSDTVQGIAFAGLPMYSSFSSLVRKAEPEYLFSPGIIAESNHSSCDKKTLPLTWRGFLSMSGEIERITGCNVFCTLAGPGASCEAYSENGIFNISSPTCLVNKVQKFRGSEQRINFISQRIDQDVIVYCNGQKKVILTKTLVIGQCIYTFTSIFSLIPSVAHSLAVELCVPGIHGWATIALVITFCFGWLLIPTTTMVVLKCLRLLTYSCSHYSTESKFKVILEKVKVEYQKTMGSMVCDICHHECETAKELESHKKSCADGQCPYCMTITEATESALQAHYAVCKLTGRFHEALKKSLKKPEVQRGCYRTLGVFRYKSRCYVGLVWMCLLTLELIVWAASADTPLLEPGWSDTAHGVGDIPMKTDLELDFAIPSSSSYSYRRRLVNPANSDETVPFHFQLERQVIHAEIQSLGHWMDATFNIISAFHCYGECKKYSYPWQTAKCFFEKDYQYETSWSCNPPDCPGVGTGCTACGIYLDKLKSVGKAYKVITLKYARKVCIQLGTEQTCKNIDVNDCLVTSSIKVCMIGTISKFQPGDTLLFLGPLEEGGLVLKQWCTTTCSFGDPGDIMSTTSGMRCPEHTGSFRKICGFATTPVCEYQGNTVSGFKRLMATKDSFQSFNVSEVHITTTKLEWSDPDSNIKDHINLILNRDVSFQDLSDNPCKVDLSTQAIDGAWGSGVGFTLTCIVGLTECSSFMTSIKVCDMAMCYGASVVNLVRGSNTVKIVGKGGHSGSTFRCCHDKDCTSNGLLASAPHLERVTGFNQIDSDKVYDDGAPPCSIKCWFAKSGEWLLGILNGNWVVVAVLVIILLISIFLFSFFCPIRSHKKQL
What is the function of this protein?
Forms homotetramers with glycoprotein N at the surface of the virion.  Attaches the virion to host cell receptors including integrin ITGAV/ITGB3.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis.  Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion.
What are the official names of this protein?
Envelopment polyprotein, Glycoprotein precursor, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the hantavirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein N]: Virion membrane; Multi-pass membrane protein. Host cell surface. Host Golgi apparatus membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host mitochondrion. Note=Interaction between glycoprotein N and glycoprotein C is essential for proper targeting of glycoprotein N to the host plasma membrane, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host cell surface. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single- pass type I membrane protein. Note=Budding probably takes place at the host plasma membrane (Probable). Glycoprotein C cytoplasmic tail is important for efficient Golgi localization (By similarity).