PharMolix/UniProtQA huggingface dataset:
Protein: NRDR_BURP0
Sequence: MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELALPAVVKKDGSRTEFDRRKIVASMQLALRKRPVAADAIDAAVARIEYQLLASGEREVRSEKLGELVMNELRQLDTIAYVRFASVYRRFEDVSEFEDVIEEFRRAAPAKTPRKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL20_SYNSC
Sequence: MARVKRGNVARKRRNKILRLARGFRGGNGTLFRTANQRVMKALCNAYRDRRRRKRDFRRLWIARINAAARLNGVSYSRLMGGLKKADVRLNRKMLAQLAVVDPGSFTNVVAAAKS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ANMK_RHIWR
Sequence: MTKMLAVGLMSGTSLDGIDAALIETDGAGHIRPIAFRSDPYAAQAREQLREAAALALSFDAPRPSPKIAAAEAMLTDRHVAAVRQLLAAARVEAGQVDVIGFHGQTIAHRPDRGWTWQIGDGAAMARALGIRVVNDLRSADVAAGGQGAPLLPVYHRALTAGMEGPVAVLNLGGVANITWLGAGEGELIAFDTGPANGLIDDWMLQETGSPYDAHGAFAARGTVDRAVLGAMLDNDWFDAPPPKSLDRADFTIQPARGLSAADGAATLTAFTAETVALALRHLPAPPRRLIVAGGGRHNPTLMKMIATATKITPEPIEALGWNGDATEAEGFAYMAVRSLKGQAISFPGTTGVAEPLTGGVTHRP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ARMET_DROYA
Sequence: MKTWYMVVVIGFLATLVQTSLALKEEDCEVCVKTVRRFAESLDDSTKKDYKQIETAFKKFCKTQKNKEHRFCYYLGGLEESATGILNELSKPLSWSMPAEKICEKLKKKDAQICDLRYEKQIDLNSVDLKKLKVRDLKKILNDWDESCDGCLEKGDFIKRIEELKPKYSRSEL
What is the function of this protein?
Required during the maturation of the embryonic nervous system for maintenance of neuronal and cuticular connectivity.  Essential for maintenance of dopaminergic neurons and dopamine levels (By similarity).
What are the official names of this protein?
Mesencephalic astrocyte-derived neurotrophic factor homolog, MANF/CDNF-like protein.
What is the protein family that this protein belongs to?
Belongs to the ARMET family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMB_SHEON
Sequence: MNLRALAAKAIFDVLEKGVSLSVALPEQQKHLASGKDKALLAELCYGVMRTLPQIEKRTAECLAKPLKGKQRIIHQLLIVGCYQLYFTRIPSHAAISETAEACRQLKFEGMVKVVNGVLRNIQRQLTPLSNESETLSYNTPGWLIKRLKTAYPGNWQEIIQQSHERPPMWLRNNRLSQSRDEYLAALDKLEIDASAGLSDDAILLAAPKDVATLPLFLEGAASVQDGAAQWAATLLAPQANELILDACAAPGGKSCHLLELEPSIKLIAVDFDAKRLERVQQNLDRLSLKAEVIHGDAANIDSWWQGEQFDRILLDAPCSATGVIRRHPDIKWLRKNHDIEELAELQRQILDHCWKWLKPGGTLLYATCSILPQENRDQISAFLARTADAKLDTLVQQASSQDIGWQITPGQHNMDGFYYARLLKATH
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS4B_MOUSE
Sequence: MASTNTNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCTEYLDRAEKLKEYLKKKEKKPQKPVKEEQSGPVDEKGNDSDGEAESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARAAMFRLHLGSTQNSLTEADFQELGRKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRADPNCIVNDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMWDMLRSLSSTKPTVNEQDLLKLKKFTEDFGQEG
What is the function of this protein?
(Microbial infection) In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (lentiviruses).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 4B, Suppressor of K(+) transport growth defect 1, Protein SKD1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein. Note=Membrane-associated in the prevacuolar endosomal compartment.
Protein: VPS10_NEUCR
Sequence: MRVRGALQAAALLASALWAAPLLAKDHPTFKTTKLDTQPNNLNYFEGSDTILFHDTHKSNLWRSDDAGATWSVVKDIPDGKVARLYMHDFDSKRAFAITDGRKHYRTTDQGKTWKTFEVDAAWDTERFDILHFHATDPDRIIFNGLHCLGFLCEEVSLYTIDDFETPAKPLRPDTLGCWWAKSSPVFTTGDSDLDKDRILCIIMGVDSIFSEDRRLVISDDFFKADKEGNIQEFEPNLAGDKPVRGVVNVAAVKRYFMVATTSANTDEMALFISTDTKKWQRAMFPNAHDDHDHKIVQEAYTVLESTNYSIQLNVMTGSKSAPMGIMFTSNYDGTYFSENLEYTNLNMFGHVDFEKIAGIQGIFLVNKVDNGKEVDEKPSTKKKLVSEITFDDGRTFDKVTADGKRIHLHSVTELNNVGRVFSSPAPGLVMANGNTGDYLGDYWEDANLYVSDDAGKTWKKALKGPHKYEFGDQGSILVAVRDSKEEDISEISYSLDHGENWVDEKLPDDLKIQPWILTTTPDSTGLQFVLIGKAKGAWHVIHIDFEGLHEATCKESDMEEWHARVDKDGEPTCIMGHTQTYPRRKKDAKCFLKKEFKLAEVETKDCDCTDQDYECDYNFERNDKGICVSRGPIPIPEGACKEGDRNGKFLGTSGYRKIPGNTCKDTKETKDKYKDVERSCGDGIGAPPDEATGELQQVDTKGKFGHWTHWEKHYLERGESSSDSSETIIMRGMNRTVDDSGPKVGPIWRTTDHGKKWDKVDFFKDDEVISIVPHPTVKDWVFFLTEGKKLIYTPDRGKRFRTFEVPQPADFEAAANGIFPLIFHPDKPNWLIWLGKKCESKNDCYRVAYGTKDGERWETLARDVYRCEFTGAEAYGRKYANRALEQILCLKHEKEGDNDSALQLVSSNDWFNQDERVRLKEAKEFATMAEFIVVATEDTEKKTLRAYASLDGSLYSEAKFPFGFEVPHQHAYTVLDSSTHAVNLFVATRMEGDKSLGTILKSNSNGTSYVVSVKNVNCDQYFYVDFEKMVGLEGVALVNVVVNPDAKSSAPKKLQTKITHNDGAQWAYLPTPRKDEFGKFPCSSSGTEKCALHIQGYTQRRDRGKTYSSEGAVGVMFGWGNVGDSLGSIKDADTFMTTDAGITWKRVKKGRWNWALGDQGSIIVLVPIRGQKTDTLEYSLDQGATWKKHTFSKEKVDIWDLTTTRSGNSQNFLIWGENSDGLFTTKIDFTKFTDHVCKYDPENLSKSDYQIFSPKHPLQPDGCLFGHVSQYLRKKPGLKCFNDFRLDPLYSKQNCTCTRSDFECDFNYELDKHGQCSLVSGLKPKDHKLWCKEHPDEIEYYEPTGFRRIPLTTCQGGLDFEKAAAVHPCPGHEDDFERKHRVSGIAIFFAVVLPVAAASAIGWWVYRHWDGKFGQIRLGEQGASTMEFFDADRPWVKYPVIALSAVVALAGAMPLVLGALWRTAKSTAERWGIGGGGGGRGGWSRLDGGGASRTFRTRDSFARGRGDYTIVDEDEGELLGEESDEEV
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin vps10, Vacuolar carboxypeptidase sorting receptor vps10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: NAGZ_SHIBS
Sequence: MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSTLIRENKLDAIMPAHVIYSDVDPRPASGSSYWLKTVLRQELCFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKASSTRLNQLHERWQEEKAGH
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR220_MIMIV
Sequence: MTQVNNWNELVSVLEGKTDVLFVELLIKVNRHINSNRFNKNFNPTTVIKSQQSIFDTFKLIFEQLSIETDTNEIFTEITSLTTNNTMTFLMTGVGKWIKFHGKETSNIHFIDDEKTIISDRTLADFLNKITEFQNQYTYFGKKPLVYYKFKDLPSGEILEYIKTFDVIPCVLTDVTPSLNYDKDNFESTLLLDQASVLTLCSNLSWGYSDTFYQLSQENKTKEQVIANKLEMDNLILGKRLLVNKSVYDGIVAKIDFTAGPTEKNRFENISKYLEIVEDCINPRFLKMKDSELICTSVAERECATIVTNNKHVWKKIKLFYKEIPCKLFVSVQLTETKYN
What are the official names of this protein?
Uncharacterized protein R220.
Protein: SYM_METTH
Sequence: MSKVFITCALPYANGPTHLGHLRSTYIPADIYARYRRLRGDDVLFVCATDEHGTPIAVKAEAEGRTPLEVATRYHEMIRGDLERCDISFDSFTRTTDELHHEIAQKFFLKLYEKGFIYEKDIKQLYCGDCQRFLPDRYVEGTCPYCGSEGARGDHCEGCGRHLEPLQLEDPRCMVCGSEPEVRDSRHYFFRLNQFQDEIREWIEGSEMPSNVRNYAIQWLREGLKDWILTRDMEWGVQVPLEGNEGKIIYVWGEAFLGYISSAAAWSKKTGRDWREYWDSGAIHFIGKDIIYHHAIFWPALLMAYGCRTPANIIAGEYLSLEGQKMSTSKNWVVWTSDFLERFDRDLLRYYLTVNAPLTRDTDFSWDDFQRRVNDELADVLGNFLHRTFSFTGRFFDGRVPAAGELTAEDLEFLESIRAAHDTVAELLDKFQFRDALMHIIKLAKRGNKYFNDQEPWKAVKESPARASTCLHLCNLLAANLGKLLRPFMPSAAGRILSIMNLEDEAWGFHELREGQVIERAKPLFSKITDEAIEEEKAKLIEEDDEVETVTIDDFTTMDIRVGVIRSAERIEGSDKLLKLIIDVGEREMQVVAGLAEKYSPEDLVERKITVLVNLKPAKLFGVKSEGMVLATGESLNILDPGDAEVGERIR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCBP1_CAEBR
Sequence: MSRRRQNDEEDEIQMKRRRGAPLIGDVEKKLQEVIGKVGDKNTGSSIEANLEKLTAFLHDDLEKYRSSIIDIVAGCAIYLPNRVTVYTTLVGLLNAKNFNFGGDVVEKLIAEQQDLLLKQKYQEAQNLAIFLCDLGNSGVLTAQSIGEYLESFIAAAFEENMPQVRNDYYIQTVLRCLPWIGKELTEKAQEQMENIVEAVGKYLEMRNKNHVPLLRVWREGSTDQEQEDYLESLSAQIENLRTANWMQNHIPRYYNTFEAVLQDALQHNLPSFSSPEHTSDMIYPYPLVVFRLFQDADCGTDSQLPSGHSIDRFLFEGEISWIIEKNQFNRKSCARELLAFADENPTAPVGFLIFETIFGQMLRLPHAPYPAIFHCSLVLELLKLKPNDYPNILCKTVDLIFSRADSMQPICIDRMVDWFSFHLSNFQYRYTWDEWKDCISNDEFSGRQVFLREVIEKCRRLGSYEKIIAALPSDFVKIHPASPEIRYLLDEEDAMSQRAETFTQMFQERQPADAFLKELKSTDENDELPYNINEFGVFVTVMLKMASKTYSHNFSALFRYKDTLKTVCDAAEQYQEKLLETLYSCWKSNQQMLMILTDKLLKMQIIDCSSVVGWLFDEKMWQEHNRQWLFEVLNQALEKLTRQINVVEKDIKDLTEKVESKEKVTEAGDVKMEEETVVDEKLKGEMEELENHKEKLDRMVSFQRNLFNDFLIAFVEEIKSAATNTSEMDGSGDVGGSESSKFLWLRGRFCHVLLAHAETLLKHSSSIAEEVFSEGADPNISECFNQFQSLRF
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing.  In the CBC complex, ncbp-1 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of ncbp-2 and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 1, 80 kDa nuclear cap-binding protein, CBP80, NCBP 80 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the NCBP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSCA_PECCP
Sequence: MALLQISEPGLSAAPHQRRLAVGIDLGTTHSLVATVRSGEAQTLVDSDGRDLLPSVVHYRRDGHSVGWQARDNAARDPENTVSSVKRLMGRSLDDIQQRYPHLPYRFHASDNGLPLIQTPAGNLNPIQVSADILSALAARAEAALGGVPDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAIYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLAEWLREQAGIHDRDDRQLDHALRAAAVKAKIALSSAESASVSIAGWQGDITREQFDSLIAPLVKRTLLSCRRTLKDAGLTPEEVLEVVMVGGSTRVPLVREQVGTFFGRTPLTSIDPDKVVAMGAAIQADILVGNKPDSDMLLLDVIPLSLGLETMGGLVEKIIPRNTTIPVARAQEFTTFKDGQSGMMIHVLQGEREMVADCRSLARFSLRGLPPLPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLSDTEIATMITDSMLNAKEDVGARRLAEQKVEAARVLESLQSALVADAELLSNDEKGVIVAASEHLHTMMQGSDPVAIEAAIKTVDQQTQEFAARRMDASIRRALAGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ALL7_CYDPO
Sequence: KMYDFGL
What are the official names of this protein?
Cydiastatin-7.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLNA_NICPL
Sequence: MSLLSDLINLNLSDSTEKIIAEYIWIGGSGMDLRSKARTLSGPVTDPAKLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGNNILVMCDAYTPAGEPIPTNKRHAAAKIFSNPDVVAEEPWYGIEQEYTLLQRDINWPLGWPIGGFPGPQGPYYCGTGADKAFGRDIVDSHYKAYLYAGINISGINGEVMPGQWEFQVGPSVGISAGDEVWVARYILERIAEIAGVVVSFDPKPIPGDWNGAGAHTNYSTKSMREDGGYEVILKAIEKLGLKHKEHIAAYGEGNERRLTGKHETANISTFKWGVANRGASVRVGRDTEKAGKGYFEDRRPASNMDPYVVTAMIADTTIIGKS
What are the official names of this protein?
Glutamine synthetase, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_ACIBT
Sequence: MPIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTGPVLVRVHSECLTGDAFASLKCDCGPQLQATQKLINEAGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANLLLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALKDQGINVVDRVPLTVGRNPFNEQYLKTKRERMDHLYQKDDF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: ARGC_NEIG2
Sequence: MSKKIKAGIVGATGYTGVELLRLLAAHPDVEVAAVTSRSEAGTAVADYFPSLRGVYGLAFQTPDEAGLEQCDIVFFATPNGIAMKDAPRLIEQGVRVIDLSADFRIRDIPTWEHWYGMTHAAPGLVSQAVYGLSELNREAVAQARLVANPGCYPTCVSLPLVPLLRQCRLKPGMPLIADCKSGVSGAGRKGNVGSLLCEAGDNFKAYGTAGHRHLPEIRQTIAGLQDGIAEGFVFTPHLAPMIRGMHATVYLHLSDGSDPETVLRDYYRDSPFMDILPAGSTPETRSVRGANLCRISIRQAAQSDVWVVLSVIDNLVKGAAGQAVQNMNIMFGLEETHGLGGIPLLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_FRATH
Sequence: MLKGIHKYLLMCFGTVLFTVQANAARIMSNNPIKEDWQCKVVDGEWSCKRAKKPKSVFDKKLTKTEKEKALADDLAWVKKPSYFVGGYYSNDNQFTKALCESKKTDLSYEKSEFDNYGTLIASGNVQVLQCDQELYGNNAIINLNSNNSAIRSLVMAGDVIVKQPSTGIVIRTTELDADMNNGTYSTGEAYFRLAREMPKTRIYDKEHFSGYLRGYAKTFKKESSGDIVLSDGYITSGDPYDNAWKITGNNIDIDTNTHMAYVKNGYFEIQDIPVMYIPYFSHPIDDRRRSGFLYPGFLQNANSGIGISVPYYFNLAPNYDLMLQSVIWSQRGIIENGTFRYMTKYFQGQFEGSLVPYDFKEGKMRSSFTLSTTGQYENINTNFKYEYVSDQNYYNDFSAGNVNLVTKTLLDREFDLTYTNDYVDSGLTVLDYGVVNPLLTVDNTPYAKLPEVKLNLTSDGYTPDYLTLSAQTLNTFFYKTAGPANTNPGAPQGTNVNAFRAYESPKIAFNFNKTWGYLKPSLELPIRYYKLNNKPTDIIKFKNSNVTSVLPIFNIDAGAYFDKDYTNENGTYTSTLHPRLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYDRINNANQLTYAIEASTTNQDNGTTLASAKIGQMAYFADRKVNLCQGNSACPNPGLMDPFSTDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQLSYKDENENIFNVSYNNIANNWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWNYNFQQKQIANIFAGLQYNAKSWAVRALWQKTAYTNQDPNNPTLLGPLVNTYMFEFELKGLGGIGNTSDISSRLQQINGYQVGEWGNGI
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: SDHF4_MOUSE
Sequence: MVSTTLSVSRMTFVWRAARPSLLNHSLRKMSYQEGKPEPAKQALKKSKLPLGRFDSLEDSPEEREPLQKFPDDVNPVTKEKGGPKGPEPTRYGDWERKGRCIDF
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954416).  Binds to the flavoprotein subunit Sdha in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit Sdhb into the SDH catalytic dimer (By similarity).
What are the official names of this protein?
Succinate dehydrogenase assembly factor 4, mitochondrial, SDH assembly factor 4, SDHAF4.
What is the protein family that this protein belongs to?
Belongs to the SDHAF4 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CLU_AEDAE
Sequence: MQFLSPQMEQKLHRATIHQITVSKTGDMPIRFRLRHLNYRNNKKQKNGKDKETTPPPTTTGAKEPLVNGHSAAVNGMNGHTSEGEQQKDKTAAEDKKKPDSDVMEIIQDTGFTVQILSPGVEPLSIQVSSMELVQEIHQLLMDREDTCHRTCFSLQLDGVTLDNFAELKNIEGLKEGSIIKVVEEPYTMREARIHVRHVRDLLKSMDPADAYNGVDCSSLTFLHTITQGDILEKKKGRSESVDCTPPEHIMPGAKDRPLLPLQPGVGKKGPQPLKVLTTSAWNPPPGPRKLHGDLMYLYVVTMEDKRFHISACPRGFFINQSSDDVFDPRPDNPSYLCHSLIDLLSQISPTFRRCFAQMQKKRTQRHPFERVATPYQVYTWSAPALEHTIDAIRAEDTFSSKLGYEEHIPGQTRDWNEELQTTRELPRETLPERLLRERAIFKVHSDFVTAATRGAMAVIDGNVMAINPGEDAKMQMFIWNNIFFSLGFDVRDHYKELGGDAAAFVAPRNDLHGVRVYSAVDVEGLYTLGTVVIDYRGYRVTAQSIIPGILEREQEQSVVYGSIDFGKTVLSHEKYLELLNNAGKHLKILPHSVLNEKEEEIELCSSVECKGIIGNDGRHYILDLLRTFPPDVNFLKLDEELSKDCKALGFPIEHKHKLSCLRQELLEAFVESRYLMFIKHAAFQLQQLNSAKLKQKQEAKDSKDSEKKEEPKAIEAAPVAKEPAKKDAAESNNNVESKEECPKKGSTDKAKDKSAGVPKVETEEAKKLMESLLSSDEKNESKEVVKRACEAVGSLKEYEFDIRFNPDVYSPGIKHVDNQSAANSLKKQKQLVKDAAEFLVKHQIPSFVHDCLDHTAAPMDGTTLTETLHSRGINVRYLGKVANLLAKIKQLEYLHTIAVSELIIRAAKHIFTSYMQNTEMMSMAAAISHFLNCFLTATTAVSHSGSLSESDALTKSGSSGGKQQRRQNKRSAGSKGGKPSFQCTQDNNEWQLLTPKSLWSQIEKELKSYWDYELLPAGAHDSADPVVSHYRLQKISLLRAFCLKTGVQILLREYNFEMKNKPTFGESDIVNVFPVVKHINPRASDAYNFYTTGQSKIQQGYFKDGYDLISEALNLLNNVYGAMHPENAQCLRMLARLSYIMGDPQEALAIQQRAVLMSERVNGIDHPYTIAEYAPLALYCFANSQISTALKLLYRARYLATIVCGENHPDIALLDSNISLILHAVGEYELSLRFLEHALALNIKYYGEKSLKVAVSYHLVARTQSCMGDFRSALNNEKETYAIYKQQLGETHEKTQESSECLRHLTQQAVVLQKKMNDIYSNGKLTSGLPPIHIQPPSMGSVLDMLNAINGIIFVQISSKEIANLKNEIEKRQKEGGTSEQAAAAQASQEEVDRMLTETMAKTAAGIPFEDHDKHELPVAAEASSSKQADNSSNASAQQVS
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCEH_SALA4
Sequence: MKYELTATEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLTEQEVQEQLDNLVKRHFLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALVTTLLLRGAQTPGELRSRASRMHEFSDMAEVESTLERLASREDGPYVVRLAREPGKRESRYMHLFCGDVDELSLQTSAPESASGDLQSRVEALESEVAELKQRLDSLLAHLGE
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: PYRE_BACAN
Sequence: MKKEIASHLLEIGAVFLQPNDPFTWSSGMKSPIYCDNRLTLSYPKVRQTIAAGLEELIKEHFPTVEVIAGTATAGIAHAAWVSDRMDLPMCYVRSKAKGHGKGNQIEGKAEKGQKVVVVEDLISTGGSAITCVEALREAGCEVLGIVSIFTYELEAGKEKLEAANVASYSLSDYSALTEVAAEKGIIGQAETKKLQEWRKNPADEAWITA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PYRE_CORGL
Sequence: MSSNSINAEARAELAELIKELAVVHGEVTLSSGKKADYYIDVRRATLHARASRLIGQLLREATADWDYDAVGGLTLGADPVATAIMHADGRDINAFVVRKEAKKHGMQRRIEGPDLTGKKVLVVEDTTTTGNSPLTAVAALREAGIEVVGVATVVDRATGADEVIAAEGLPYRSLLGLSDLGLN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: VATC_METS3
Sequence: MADEIATLISSAGLTNETFLVLCVIAVIVIGAIVVIITSRPILDIYPYLTPSASVRARKGRLFDEKQLSEIVETNNVHEFENYLKGVPDYADVLEEYPVDKALDIQCADTYEFVARIAPKEIRSSFVVMSKKTDINNIKSLLTAKEVGLTEEETEDLLIPRGVLYEDLRSLIDADGVTDVVTSLDGTEYAAVLEDALPKYENSGMVLALESALDKYYLESLLRSSNVPADENKQILFSYVGTQVDIANLKLIIRAKKDNLSYDDIAPYILEDGYQLREWKLKDLMESPDVTNVISGLEGTKYSDVLTDAMAKYNENASIAVFEKALDAYLSKSAKSLSMKKPLGIGPIIGYVSQKETEIKNLKIIARAKREAGFPNSKIMEMLI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: FLIW_RHOBA
Sequence: MRIDSHRFGTLELNADQLFLFPQGLIGMESLHQWALIPDPDNASVAWLQSAARGDRALAVISPRAFFPDYRVHIGRRDLSSLHLTSGSEVYVMTTVAGHVGKLTTNLRAPLMLNLDRRLGCQVITNDDRPMRQPLPTVAAESAKPLPTSQVRAA
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTG_SALPC
Sequence: MSPSDVPINWKRNLTVTWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGLVFSITFLFSAIASPFWGGLADRKGRKIMLLRSALGMAIVMLLMGMAQNIWQFLILRALLGLLGGFIPNANALIATQVPRHKSGWALGTLSTGGVSGALLGPLAGGLLAGHYGLRPVFFITASVLFICFLLTFFFIRENFLPVSKKEILHVREVVASLKNPRLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNIAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILIVALIISVLLLIPMSFVQTPWQLALLRFLLGAADGALLPAVQTLLVYNSTNQIAGRIFSYNQSFRDIGNVTGPLMGAAISASYGFRAVFCVTAGVVLFNAIYSWNSLRRRRLAIE
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBE2S_DROGR
Sequence: MSSQYSNVENLSPQTIRQVMKELQDMESTPPEGIKVLINESDVTDIQALIDGPAGTPYAVGIFRVKLTLSKDFPQTPPKAYFLTKIFHPNVASNGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGKMLLERYDDYSQRARMMTEIHAQPAKCGAGASDAKDDDGPSTKKHAGVDKKLQDKKKEKLLKEKKRMLKRL
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.  Acts by specifically elongating polyubiquitin chains initiated by the E2 enzyme vih/UbcH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 S, E2 ubiquitin-conjugating enzyme S, Ubiquitin carrier protein S, Ubiquitin-protein ligase S.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.