PharMolix/UniProtQA huggingface dataset:
Protein: RPA49_DICDI
Sequence: MSNLTVNVIEEKNLGDNKPCVLKFSQGLPPLSFIEKEPEFISMSTKNKRHRVVLTNTDQLEYESEDKDSKYAKYAIGIFDKNTKQLKIVPTKIQTMNQSVIGYTLTLDSSSVISREERYDKIKKLADSFGSKITKKKMQKMEMENVENLDYEKTTKSIDAVKNELADIESNEKPFDLPDFDAETNDVRKIYNIEAILPPRIFFGLNHQPFLDIISKTSEAPSYLPEYFKDQLKRFEDIKDEEKVVYNCKLLTFMWYSMILMKSKGGHEPLIKEGCTSEVINFLVSIFGSKINHKKYNISQDDKLKIYNYLAIFALKLEDFQITDIKSLAQSLSLTSSSFEKHFTRVGCKVVRIGSEKRSVRLEAPLKLPKARFSN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit rpa49, RNA polymerase I subunit A49, DNA-directed RNA polymerase I subunit E.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GATC_MYCPA
Sequence: MSQISRDEVAHLARLSRLALTDAELDSFAGQLDAILTHVSQVQAVDVTGVEPTDNPLKDLNVTRPDEPMPCLTQAEALAEAPEAVDGRFAVPQILGDE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: LIPA_DELAS
Sequence: MTTNTVVREAQSQAEYNPLAKQKAAAKLSRIPIKVEHGEALKKPDWIRVKAGSPTTRFYEIKDILRANKLHTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDTNEPLNLAKTIAELRLKYVVITSVDRDDLRDGGSGHFVECIKNIRELSPLTQIEILVPDFRGRDDRALEILKAAPPDVMNHNLETAPRLYKEARPGSDYQFSLNLLKKFKALHPKVPTKSGIMVGLGETDEEILQVMRDMRAHDIDMLTIGQYLAPSNSHLPVRRYVHPDTFKMFEEEAYKMGFTHAAVGAMVRSSYHADQQAHAAGV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VOSA_COCSN
Sequence: MAFSYNYSLQASYPSQRAYVPYQQTQVPTPSPIYSLPITNTTTSGALSPSSCFLSVRQQPKEALVTVKGKEKFRKPLDPPPMLELKVSSDIDPSQQFLQNPYLFVSVSLYKHDKDEPIEGTPFDVLAGTLVSSLHRLKDVNNKDGAFFIFGDISIKVQGTYRLRFTLYELQPSYFTLSDLEQHKDLERYQGAALDPPEYGTYQCLGHVLSDKFNVVLPKDFKGLEESTYLSRAFSDQGVRLRLRKEARGMMSNKRSISGSGDLTSDQSQQQQQQQPLAKKRREDSVESANPSSLMSGFYQNVSPFVNTPYLQSQGLQGQTLQNQGLQAPVRHDTSYAWNLAYDPSFMG
What is the function of this protein?
Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity).  The complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity).  Regulates spore viability, trehalose accumulation, and tolerance to thermal and oxidative as well as ion stresses (PubMed:26399184).  Positively regulates conidial pigmentation and pathogenicity on barley (PubMed:26399184).
What are the official names of this protein?
Spore development regulator vosA.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VosA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LFTR_XYLFT
Sequence: MHSQPYLLSPTPNTPFPPAEHALHEPNGLLAIGGDLTPQRLLAAYRSGIFPWFTEGQPPLWWSPDPRTVFHSDNIHLSRRFRRSLRTSTWTVRADTMFAAVIDACASTPRRGQDGTWITANMREAYLTLHQHGYAHSVEVFDGTMLVGGIYGVAIGRMFFGESMFSTHNGASKIALASLAYFLHTHSVPLIDAQVENQHLLNLGAERWPRRDFLTSVRRLITQTELPACWSVLFGEKLSRDLV
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2914_MYCBT
Sequence: MTTLKTMTRVQLGAMGEALAVDYLTSMGLRILNRNWRCRYGELDVIACDAATRTVVFVEVKTRTGDGYGGLAHAVTERKVRRLRRLAGLWLADQEERWAAVRIDVIGVRVGPKNSGRTPELTHLQGIG
What are the official names of this protein?
UPF0102 protein JTY_2914.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RPOC1_MAIZE
Sequence: MIDQYKHKQLQIGLVSPQQIKAWAKKILPNGEVVGEVTRPSTFHYKTDKPEKDGLFCERIFGPIKSGICACGNSRASVRENEDERFCQKCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKGLPSYIANLLDKPLKKLEGLVYGDFSFARPSAKKPTFLRLRGLFEDEISSCNHSISPFFSTPGFATFRNREIATGAGAIREQLADLDLRIIIENSLVEWKELEDEGYSGDEWEDRKRRIRKVFLIRRMQLAKHFIQTNVEPEWMVLCLLPVLPPELRPIVYRSGDKVVTSDINELYKRVIRRNNNLAYLLKRSELAPADLVMCQEKLVQEAVDTLLDSGSRGQPTRDGHNKVYKSLSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHQCGLPLEIAIKLFQLFVIRDLITKRATSNVRIAKRKIWEKEPIVWEILQEVMRGHPVLLNRAPTLHRLGIQAFQPTLVEGRTICLHPLVCKGFNADFDGDQMAVHLPLSLEAQAEARLLMFSHMNLLSPAIGDPICVPTQDMLIGLYVLTIGNRLGICANRYNSCGNSPNKKVNYNNNNYYKYTKDKEPHFSSSYDALGAYRQKRIGLNSPLWLRWKLDQRIVGSREVPIEVQYESFGTYHEIYAHYLVVGNRKKEIRSIYIRTTLGHISFYREIEEAIQGFSRAYSYTI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DLDH3_HALMA
Sequence: MVVGDVTTSTDVLVIGAGPGGYVAAIRAAQLALDVTLVEKGEYGGACLNRGCIPSKALIHGSKLASEAGQAEELGIYADPTVALDEMINWKDGVVDQLTSGIEQLCTAAGVNLLKGTAEFADENKVRIIHQGEGQGSESLKFENCIIATGSRPIEIPGFGFEDERIVSSDGALNFDTVPDELVIVGAGYIGMELATVYSRLGSDVSVIEMLEQALPSYEEDIASIVRKRAERLGVDFHFGYTADSWAASDGKAVLTAVPADEAAHDSDIELTADRILVAVGRRPVTDTLSIDDAGVETNAQGFIPTDSTCRTNKEHIFAVGDVAGEPMLAHKGSKEGEVAAEVIAGEPAAVDYQALPAAVFTDPEIGTVGLTENEAANKGMTPVTGEFQFQASGRALTANRAEGFVRIIATKETERVIGAQIVGPEASELIAEIAAMIEMGAKLEDIGSTVHTHPTLSEAIMEAAQNAREKAIHRRN
What are the official names of this protein?
Dihydrolipoyl dehydrogenase 3, Dihydrolipoamide dehydrogenase 3.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_RICFE
Sequence: MVSSNFYKNLGPRKLTAIIDFLHDIIEPPKIHEDIAIHDIKILQEASPNDISFLSNPKYSEFLKTTKAAACIVPKNFTGEANPNTVLIHAENSYFAYGKLIDFFYTPIKSYPAKIMKSAIVADSATIGKNCYIGHNVVIEDDVIIGDNSIIEAGSFIGRGVTIGRNARIEQHVSINYTIIGDEVVILAGAKIGQDGFGFSTEKGVHHKIFHIGIVKIGNNVEIGSNITIDRGSLQDTIIEDLCRIDNLVQIGHGVKIGKGSIIVAQAGIAGSSTIGKYCALGGQVGIAGHLNIGDGTQVAAQGGVAQNIEAGKIVGGSPAVPIMDWHRQSIIMKQLVKTSNSKLKK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: CREA_FLASU
Sequence: MQMPKTLRIRNGEKVKSTFSAQEYANRHAKLRAHLAAENIDAAVFTSYHNINYYSDFLYCSFGRPYALVVTQDDVISISANIDGGQPWRRTVGTDNIVYTDWQRDNYFVAIQQALPRARRIGIEHDHLNLQNRDKLAARYPDAELVDVAAACMRMRMIKSAEEHEMIRHGARVADIGGAAIVEALRDQVPEYEVALHATQAMVRAIAETFDNVELMDTWTWFQSGINTDGAHNPVTTRKVNKGDILSLNCFPMIAGYYTALERTLFLDHCSDDHLRMWQANVEVHEAGLKLIKPGMRCSDIAKELNEIFLKHDLLQYRTFGYGHSFGTLSHYYGREAGLELREDIDTVLEPGMVVSMEPMIMLPEGRPGAGGYREHDILIVNENGAENITKFPYGPERNIIRK
What are the official names of this protein?
Creatinase, Creatine amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24 family. Creatinase subfamily.
Protein: SYS_HELP2
Sequence: MIDKKLLLQDFEMVALSLKKRNHAMDDGLERLREVITHYKKQLIELEGLQAFQNKVSKEFGIKMAQKADTSDLKKELESNKIKLNELSKSVSELEQQIDLKLSIIPNLVDEKTPLGANEEDNIEIKKILTPRVFNFKPKEHFELAQQNGWIDFESGVKLAKSRFSVIRGFGAKIYRALIYLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLYNDTIISVENLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDAMQECMLESASEILRALELPHRFVQLCSGDLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQADGSIHIPKALEKYL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNR2_LACLA
Sequence: MVQLSELASALNQTESKGVFSKHPKGFGFVHPEDATDKTNDIYIGKNDTKFAMDGDKVTVKVTYPKTEKRGASGQITKINERAVVDTVGTYRSLSNRQVKALGYKGRIELYNDRISDTLYIKQPLSGVQEEDVVSLKITQYPTNTKTFEGKITGIIGHKGEVGLDILEVLCAMKIPQEFSSETLAEAEAFSEKLTDSDLQDREDYRNEITYTIDGDDSKDLDDAIHVKKLSNWHFELGVHIADVSHYVTEGSSLDEEAYSRATSVYVTDRVVPMLPVKLSNNLCSLNEAQERLTMSCLMEIDDKGKIVSYKISPSVIKTTYRMTYNNVNKMIHQGQEGHREALENFFKITDSIKVAVELHEILETMRKDRGMIEFDESEAKIILDEKGHPIEIVKRDRDTAERMIESFMLMANETVALDFQKKKLPSLYRVHDNPKEKSFAKLMEAAANAGFSLNSDSHQAINFFADEIKGTSSEKALTYQLRHTMSTAVYSEKNTKHFGLAATNYTHFTSPIRRYPDLIIHRLLHLYPSDHSNHTKDEWKERLPEIASHSSDMEHRAVVTERIIDAMKKAEYMSERIGEVYTGTITGLQKFGIFVALDNTVEGLIRVPNLHTGTTEELEFDEEASIFKGKKSETVYQIGQEIKIRVIAANKRKGTVDFEQIAPE
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
What are the official names of this protein?
Ribonuclease R 2, RNase R 2, VacB protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPL_RAT
Sequence: MYLLPLPAAARVALRRLGVRGLWDRGLSTADMTKGLVLGIYSKDKDDDVPQFTSAGENFNKLVSGRLREMLNISGPPLKAGKTRTFYGLHQDFPSVVVVGLGKRSAGVDDQENWHEGKENIRAAVAAGCRQVQDLELPSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKVAVSAKLHGSGDLEAWEKGVLFASGQNLARQLMESPANEMTPTRFAEVIEKNLKSASSKTEVHIRTKSWIEEQEMGSFLSVAKGSEEPPVFLEIHYTGSPNATEAPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRARNGKTIQVDNTDAEGRLILADALCYAHTFNPKVIINAATLTGAMDVALGSGATGVFTNSSWLWNKLFEASVETGDRVWRMPLFEHYTRQVIDCQLADVNNLGKYRSAGACTAAAFLREFVTHTKWAHLDIAGVMTNKDEIPYLRKGMSGRPTRTLIEFLLRFSKDSS
What is the function of this protein?
Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides (PubMed:6108111, PubMed:12675513).  The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme (By similarity).  For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates (By similarity).  Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status (PubMed:12675513).
What are the official names of this protein?
Cytosol aminopeptidase, Cysteinylglycine-S-conjugate dipeptidase, Leucine aminopeptidase 3, LAP-3, Leucyl aminopeptidase, LAP, Peptidase S, Proline aminopeptidase, Prolyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAN1_BPT4
Sequence: MHVSNFTAGLLLLVIAFGGTSIILKHKVERLETSVTEITKTANENALALNNLRIQYNYIDAMNNKNREAIAAIERENEKLRKDAKKADVVAHKPGLVEKQINNSFNKFAEDIQDLSK
What is the function of this protein?
Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit.  The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans.  Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex (By similarity).
What are the official names of this protein?
Spanin, inner membrane subunit, i-spanin.
What are the subcellular locations of this protein?
Host cell inner membrane; Single- pass type II membrane protein; Periplasmic side.
Protein: RL35_ECO27
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLIIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CNGA3_BOVIN
Sequence: MAKISTQYSHPTRTHPSVRTMDRDLDCIENGLSRTHLPCEETSSELQEGIAMETRGLAESRQSSFTSQGPTRLSRLIISLRAWSARHLHQEDQRPDSFLERFRGAELQEVSSRESHVQFNVGSQEPPDRGRSAWPLARNNTNTCNNSEKDDKAKKEEKEKKEEKKENPKKEEKKKDSVVMDPSSNMYYHWLTVIAVPVFYNWCLLVCRACFDELQSEHLMLWLVLDYSADILYGMDMLVRARTGFLEQGLMVMDASRLWKHYTQTLHFKLDVLSLVPTDLAYFKLGMNYPELRFNRLLKLARLFEFFDRTETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNVSNPEYGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYLFVVIDFLVGVLIFATIVGNVGSMISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLRKVRIFQDCEAGLLVELVLKLRPAVFSPGDYICKKGDIGREMYIIKEGKLAVVAEDGITQFVVLGDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPEAKKALEEKGRQILMKDNLIDEELAKAGADPKDIEEKVEHLETSLDSLQTRFARLLAEYNATQMKVKQRLSQLESQVKMGLPPDGDAPQTEASQP
What is the function of this protein?
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger.  This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors.  Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity).  Could be responsible for cGMP-induced calcium entry in cells other than sensory cells.  Might be involved in chemotaxis of sperm.
What are the official names of this protein?
Cyclic nucleotide-gated cation channel alpha-3, Cone photoreceptor cGMP-gated channel subunit alpha, Cyclic nucleotide-gated channel alpha-3, CNG channel alpha-3, CNG-3, CNG3.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA3 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YRA2_CANGA
Sequence: MSQNTKHHRVTNYRRRDLRNTLESRLGLPVEKRRLVPQLFRLKITNIGLDVSDYTILDIIKEFGEPEYINFRDHKDSRSCISDFKDNEIATKLIEKYNNFEINGKSIQVTLLDQQKRKRDADQERRKLRHGPRGGYGSHYTKSQKPIEQRNKTVDELNAELDAYMKES
What is the function of this protein?
Involved in export of poly(A) mRNAs from the nucleus.  Recruited to the coding sequences as well as poly-A sites of active genes (By similarity).
What are the official names of this protein?
RNA annealing protein YRA2.
What is the protein family that this protein belongs to?
Belongs to the YRA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECA_PSEAB
Sequence: MDENKKRALAAALGQIERQFGKGAVMRMGDHERQAIPAISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAEAQKQGATCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVSPPFRQAEFQILYGKGIYRTGEIIDLGVQLGLVEKSGAWYSYQGSKIGQGKANAAKYLEDNPEIGSVLEKTIRDQLLAKSGPVKADAEEVADAEAD
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_PSEF5
Sequence: MTTKLKNASNLSESAQVDQQSVQPFTRSQKVYVQGSRPDIRVPMREITLDVTPTDFGGEINAPVTVYDTSGPYTDPNVVIDVRKGLGDVRSAWIEDRGDTERLAGLSSNFGQQRLADPELTKLRFAHVNNPRRAKAGANVSQMHYARKGIITAEMEYVAIRENMKLQEARAAGLLKQQHAGHSFGASIPKEITPEFVREEIARGRAIIPANINHVELEPMIIGRNFLVKINGNIGNSALGSSIEEEVAKLTWGIRWGSDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWELFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFDEICEIMKAYDVSFSLGDGLRPGSIADANDEAQFGELETLGELTKIAWKHDVQCMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARSYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREYAANQRIEAVDVDVAKGLAEQAERFKQEGSQLYKKV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RS7_MYCSM
Sequence: MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLEGKKSLAERIVYGALEQAREKTGTDPVVTLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLALRWLVNFSRQRREKTMVERLANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL24_CLOP1
Sequence: MKVHVRKNDTVVVISGKDKGKTGEVLRVIPKTGKVVVKGVNLVKKHQKPNRQNMQGGIIEMEAAINSSKVMLFCEKCKKATRISHKLLEDGAKVRVCKKCGETF
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RS17_STRGC
Sequence: MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKKYKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DNAG_LEGPN
Sequence: MSGLIPQPFIDDLLNRTDLVELIDGYVPLKKRGNSHIACCPFHNEKTPSFNVVAKKQFYHCFGCGASGNAISFVMNYLNQGFTDAVETLRRAWVKCPRDGTGEKHKSSLNLYNLMSEVSQYYQKKLKYNGQVAIDYLRNRGLSGEIAKRYHLGYAPEGWHNLEKAFPNNQRELLSTGMLIKSDEGKIYDRYRNRIMFPIHDRNGRVIGFGGRVLDKDQKPKYLNSPETVLFQKSRELYGLHQVLSQQKNPDSIIVVEGYMDVIALAQHGIFNVVATLGTATSTFHIQLLAKHTKHLIFCFDGDAAGKQAAWRALESSLPHLNAGLDAGFIFLPNEHDPDSLVRNEGKNGFLELLQQATPLHRFFFDTLSKDINLSNPAGKTQLINAVKPYLQKMVEGSYKQLLIDDLSRLTHIESHRLTNLITDKSESKPEVQAAISRSPLRIAIALLLQNPEIYSIAIQQINPALLHEQEHHILLKLLQQLKDKPNANTATLIEFWRNSSYFELIVKLAAWDHQVPEQELTKEFIDVLLFLQKQNREILIRQYIEKSRKTGLTEAERLSLQNLLKERHGQAEIEK
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: WNT2_HORSE
Sequence: MNAPLGGIWLWLPLLLTWLTPEVSSSWWYMRATGGASRVMCDNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELRSCSCDPKKKGTAKDSKGTFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANKKFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSRVTRMTKCECKFHWCCAVRCQDCLEALDVHTCKAPKSADWASPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity).  Functions as upstream regulator of FGF10 expression.  Plays an important role in embryonic lung development.  May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: ZRAR_ECOLI
Sequence: MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALDYLIKPLDFDNLQATLEKALAHTHSIDAETPAVTASQFGMVGKSPAMQHLLSEIALVAPSEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQIISVDVRLIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIPLGQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR
What is the function of this protein?
Member of the two-component regulatory system ZraS/ZraR.  When activated by ZraS it acts in conjunction with sigma-54 to regulate the expression of zraP.  Positively autoregulates the expression of the zraSR operon.
What are the official names of this protein?
Transcriptional regulatory protein ZraR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_SHEON
Sequence: MKFDPTSPSLNIMLANPRGFCAGVDRAISIVERALELFSPPIYVRHEVVHNRYVVQNLKDRGAVFVEELDQVPDNNIVIFSAHGVSQAVRAEAKARGLRVFDATCPLVTKVHLQVTRASRKGIECILIGHAGHPEVEGTMGQYDNPNGGVYLIESPADVETLEVRDPNNLCFVTQTTLSVDDTLDIISALLKRFPSIEGPRKDDICYATQNRQDAVRNLSADVDLLIVVGSKNSSNSNRLRELALKTGTQSYLVDTADDIDSSWFENITKVAVTAGASAPEVLVQQVVQAIAKLAPSVVTEVEGRKEDTVFAVPAELR
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: END4_ERWT9
Sequence: MKYIGAHVSAAGGVDRAVERASELEATAFALFTKNQRQWHAAPLTDEVISAFRLACEKHRYTPAQILPHDSYLINLGHPVAEALEKSRDAFLDEMNRCQQLGLTLLNFHPGSHLQQITEDECLKRIAESINIVLNNTAGVTAVIENTAGQGSNLGFRFEHLAAIIDGVEDKSRVGVCIDTCHAFAGGYDLRSEEACVNTFAEFERIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKAAFSWLMKDKRFDGIPMILETIDPEIWKDEIAWLKSEQK
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.