PharMolix/UniProtQA huggingface dataset:
Protein: RLME_WOLTR
Sequence: MLAIKTRVKTAKGRKLSSTRWLHRHLNDQYVQKTNKDSYRSRSAYKLIEIDNKFKLLQAGQKIVDLGASPGGWSQVASQKGVKVVAIDIKPVNTISGVKYIQYDINELETLRERFKDQKFDVILSDMAPESCGLKSLDHIRIMLLCEAALNFAKHFLNYGGKFVVKIFQGESDKDFYNELKKMFKIVKYFKPKSSRSESTEMYLVGLGFISNSFPI
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALS2_HUMAN
Sequence: MDSKKRSSTEAEGSKERGLVHIWQAGSFPITPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFHSLALVQCLPSQDLKPVPERCNQCSQLLITMTDKEDHVIISDSHCCPLGVTLTESQAENHASTALSPSTETLDRQEEVFENTLVANDQSVATELNAVSAQITSSDAMSSQQNVMGTTEISSARNIPSYPDTQAVNEYLRKLSDHSVREDSEHGEKPVPSQPLLEEAIPNLHSPPTTSTSALNSLVVSCASAVGVRVAATYEAGALSLKKVMNFYSTTPCETGAQAGSSAIGPEGLKDSREEQVKQESMQGKKSSSLVDIREEETEGGSRRLSLPGLLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTEDFQPGLYYSGRQDPTEGDNLPENHSGSKTPVLLSCSKLGYISRVTAGKDSYLALVDKNIMGYIASLHELATTERRFYSKLSDIKSQILRPLLSLENLGTTTTVQLLQEVASRFSKLCYLIGQHGASLSSFLHGVKEARSLVILKHSSLFLDSYTEYCTSITNFLVMGGFQLLAKPAIDFLNKNQELLQDLSEVNDENTQLMEILNTLFFLPIRRLHNYAKVLLKLATCFEVASPEYQKLQDSSSCYECLALHLGRKRKEAEYTLGFWKTFPGKMTDSLRKPERRLLCESSNRALSLQHAGRFSVNWFILFNDALVHAQFSTHHVFPLATLWAEPLSEEAGGVNGLKITTPEEQFTLISSTPQEKTKWLRAISQAVDQALRGMSDLPPYGSGSSVQRQEPPISRSAKYTFYKDPRLKDATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPNGDYIEGYFSGEWGSGIKITGTYFKPSLYESDKDRPKVFRKLGNLAVPADEKWKAVFDECWRQLGCEGPGQGEVWKAWDNIAVALTTSRRQHRDSPEILSRSQTQTLESLEFIPQHVGAFSVEKYDDIRKYLIKACDTPLHPLGRLVETLVAVYRMTYVGVGANRRLLQEAVKEIKSYLKRIFQLVRFLFPELPEEGSTIPLSAPLPTERKSFCTGKSDSRSESPEPGYVVTSSGLLLPVLLPRLYPPLFMLYALDNDREEDIYWECVLRLNKQPDIALLGFLGVQRKFWPATLSILGESKKVLPTTKDACFASAVECLQQISTTFTPSDKLKVIQQTFEEISQSVLASLHEDFLWSMDDLFPVFLYVVLRARIRNLGSEVHLIEDLMDPYLQHGEQGIMFTTLKACYYQIQREKLN
What is the function of this protein?
May act as a GTPase regulator.  Controls survival and growth of spinal motoneurons (By similarity).
What are the official names of this protein?
Alsin, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis 2 protein.
Protein: HIS4_DESAP
Sequence: MLIIPAVDLRGGRCVRLFQGRADQETVYSTDPVAVARTWEEQGARRLHVVDLDGAFTGKPQNSGVVLDIVKSVNIPVQVGGGIRNPENVKCYLEHGVDRVILGTAALTNPEFLDAVVAAYGERIVVGVDCRDGRVCVQGWEQTAATDVLPFLEELVRRGVRRVVFTDVKRDGTLEGPNLEEIARVAAHTELKVIASGGVSRLEDLRALKKLEHLGVDSVIIGKALYAGTITLAEALALERKEKDNVGQEDHSLPRCEPGPRG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBIX_ECOL5
Sequence: MMYHIPGVLSPQDVARFREHLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSALYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGCMRTDLSATLFLSDPESYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSHYGESEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.
Protein: RL10_SALPA
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTQFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GASR_MASNA
Sequence: MELLKLNSSVQGPGPGSGSSLCHPGVSLLNSSSAGNLSCEPPRIRGTGTRELELAIRITLYAVIFLMSIGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLNLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTVVQPVGPRVLQCMHRWPSARVRQTWSVLLLMLLFFIPGVVMAVAYGLISRELYLGLRFDGDNDSDTQSRVRNQGGLPGGTAPGPVHQNGGCRHVTVAGEDNDGCYVQLPRSRLEMTTLTTPTPGPGLASANQAKLLAKKRVVRMLLVIVLLFFLCWLPIYSANTWCAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
What is the function of this protein?
Receptor for gastrin and cholecystokinin.  The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Gastrin/cholecystokinin type B receptor, CCK-B receptor, CCK-BR, Cholecystokinin-2 receptor, CCK2-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MRAZ_NITEC
Sequence: MFRGSTQLNLDSKGRLAIPAKYRNELFANCGGNIVVTADPSRCLLIYPQPVWEPIEKKLSGFSSFNPQIRSLQRLIIGNACDVEMDGSGRILISAPLRQFAGLQKEVVLAGQGEKFELWDMAKWDLEIDTATACKDGDIPPELEGFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: KYNU_XANC5
Sequence: MTDLLSRAHAVALDAADPLRGLRDAFVFPQHGDDDQTYFVGNSLGLQPRAARAMVDEVLDRWGALAVEGHFTGPTQWLTYHQLVRDGLARVVGAQPGEVVAMNTLSVNLHLMMASFYRPTAERGAILIEAGAFPSDRHAVESQLRLHGLDPATHLIEVDADEPNGTVSMTAIAEAIAQHGPRLALVLWPGIQYRTGQAFDLAEIVRLARAQGAAVGFDLAHAVGNLPLTLHDDGVDFAVWCHYKYLNAGPGAVGGCFVHARHANSDLPRMAGWWGHEQQTRFRMDPQFVPSPGAEGWQLSNPPVLALAPLRASLALFDQAGMAALRAKSEQLTGHLEQLIHARVPQALQIVTPAEPARRGCQLSLRVAGGRARGRALFEHLHAAGVLGDWREPDVIRIAPVPLYNRFSDLHTFVEQVEAWAAA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: LPXC_AERHH
Sequence: MIRQRTLKTSVQATGVGLHSGRKVTMTFRPAPVNTGIVYLRTDLNPVVELPANADQVRDTVLCTALVNEAGVRVSTIEHLSAALAGMGIDNLYVEVDAPEIPVMDGSAHPFIYLLQEVGIREQNAPKQFVRIKQSIRVEDGDKWAEFHPYRNGFKMDLEIDFQHPVFEGRNQRCVLDFSGASFVKEISRARTFGFMRDIEYLRSQNLALGGSLENAVVLDDYRVLNEDGLRYEDEFVKHKMLDAIGDLYMCNRSIIGEFRAYKTGHALNNKLLRALLAKQEAWELVTFEGEGDKAPIAYYDNGLVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: EX7L_CERS5
Sequence: MSDLFEDPAPARNTPEYTVSELSGAVKRVIEGEFGLVRVRGEIGRVSRPASGHLYFDLKDDRAVIAAICWKGQAGRLSVRPEEGMEVVATGRMTTFPGQSKYQIIVEDMAPAGAGALMAMLEKRRAALAAEGLFDAARKRPLPFLPRVIGVVTSPSGAVIRDILHRLRDRFPSHVLIWPVAVQGEKCAPEVAAAIRGFNALPDGGPIPRPDLLIVARGGGSLEDLWGFNEEIVVRAAAESRIPLISAVGHETDTTLIDHAADRRAPTPTAAAEMAVPVRLDLLAGLDGQGARLSRCAAETIRRRDQRLRDLSRALPRLDSLVAGPSQRFDLWSARLSGALGQSVAARRARLEPLGAHLRPRLLADLVARQKDRLADRGRGLETCLGRRSERARDRFEALSGRLAPAFARLVAESERTNRRDAAALGALAARLEAAPEARLLRLADRLEALDRLRQTLGYRETLRRGYAVVRADGEVVTTKTAAERAASLEIEFQDGRLTLGARKPRKGKAEPPAQGSLL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1096_ARCFU
Sequence: MVRRKMDEKGVSPVIGVILMVAITVILAAVIASFVFGMSNVAPAAPPSAQLQVRTGSSADTVELKHMGGDPINCTSIKVLVNGKEESNALGSSGGCSDNLLKVGETETITLSGYGGQYVELTLVDIQTNKPILMTHVTVGG
What are the official names of this protein?
Uncharacterized protein AF_1096.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HMGN2_RAT
Sequence: MPKRNAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAEDGDAKTDQAQKADGAGDAK
What is the function of this protein?
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer.  May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).
What are the official names of this protein?
Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the HMGN family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation.
Protein: HDRB1_METAC
Sequence: MKAIESIPDRKLLLFKSCMVGQEYPGIETATSYVFDRLGVDYCINDEQSCCTGIGHYTDVFEGLTTAAIAARNFAVARKCGYPNITCLCSTCYAINKDACELLNTNDGVREKVNSIFREKGFDDLVYEKDSMNPRTNIYHAVEVLLSKVEKIREEIKFDFPGVKAASHHACHYYKVKYLDVIGNPENPQLIDTIAEACGASPVRWYEDRTLTCGMGFSQLHLNKSTSLQVTKTKLDSLQRAGVELMIHMCPNCHIQYDRYQPVIEKEFGVEYDMVHMNIAQFVALSMGADPYKVCGFQTHSVPLEGFLEKTGII
What is the function of this protein?
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).  Probably involved in methylotrophic methanogenesis but not in aceticlastic methanogenesis.
What are the official names of this protein?
Ferredoxin:CoB-CoM heterodisulfide reductase subunit B.
What is the protein family that this protein belongs to?
Belongs to the HdrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXR1_EMIHU
Sequence: MAAAEAQYDLLVIGGGSGGLACSKRAASHGKKVAVCDFVKPSPPGTTWGLGGTCVNVGCIPKKLMHQAALLGEGMTDAESFGWEVAAPKHNWETMVGNVQGHIKSLNFGYRSDLMSNGVKYYNAYATFLDPHTVEAVDKKGKVTKITASEIVICTGGRPRYPDIPGAKELGITSDDVFALKSPPGRTLVVGASYVALECAGFIKGVGYDTTVMMRSIPLRGFDQQMAGLCKTYMQEHGVAFIEGAVPTAVEATPSGAKKVSWKLADGSVGSGEYDTVLFAIGRDVCTSAIGIDKAGVKLSSNGKVPTVNEQTNVPHIYAIGDIIDGEALNPPSATTELTPVAIQAGKLLADRLYAGKSALMDYSMVATTVYTPLEYGAVGLPEEEAIKLHGEDNIEVYHSYFKPLEWTLPHRGDNVCYAKLICLKPEGERVIGLHVCGPNAGEMTQGFAVAIKAGATKAHFDDTVGIHPTVAEEFTLLAATKRSGDSAEKSGCUG
What are the official names of this protein?
Thioredoxin reductase SEP1, EhSEP1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Protein: PLPC_MANHA
Sequence: MKIMKLAGAVAIFSLFLTACNDKAEKLKVGVISGPEHKVMEVAAKIAKEKYNRDVELVVFTDYATPNAALDKGDLDLNAFQHKPYLDNQIQEKGYKLVPVGNTFVYPIAAYSKKIKSLAELKDGDTIAVPNDPTNLARALILLEKQDLIKLRADAGLKATSVDIIENPRKLVIQEIEAPLLPRTLDDVAFSIINTTYAGQNGLTPTKDGIFVEDKDSPYVNLIVARENNQHSEAVKDLVKAYQTEEVYNKANEEFKGAMIKGW
What are the official names of this protein?
Outer membrane lipoprotein 3, PLP3.
What is the protein family that this protein belongs to?
Belongs to the NlpA lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: IF1C_ASACA
Sequence: MKEQKLIHEGLIIESLPNGMFRVRLDNEDLILGYVSGRIRRSFIRILPGDRVKIEVSRYDSTRGRIIYRLRNKDSND
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UPP_LACGA
Sequence: MGKFTVLNHPLIQHKLTIIRKKDTGTNEFRQIVGEIGGLMVYEMTRDLPLKNVEIETPIGKSTQKELAGKKLVIVPILRAGLGMVDGVLQMIPSAKVGHIGMYRDEETLKPHEYFFKMPPDIEERECIIVDPMLATGGSANMAIGALKKRGAKNIRLAVLVAAPEGVKAVQEANPDVDIYAAEEDEKLMDNGYIYPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PMN14_PINMG
Sequence: MRSLLVLLALAACASAQFFIRGGDDDNGFFGDDDNGYYYPRYFPIYNRFPIYRPIYYRPQIYYPIYRPIFGYGGYGYGGYGGYGYGGYGYGGYGYGGYGGYGYNPYSYGGFYRFGDDDNGFDD
What is the function of this protein?
May be involved in calcification of the prismatic layer of the shell.
What are the official names of this protein?
Prismalin-14.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAJ_FRATH
Sequence: MQQKCYYEILNISKTASGVEIKRAYRKLAMKYHPDRNPGDKEAEIKFKEISEAYEILSDDSKRSRYDQFGHAGVNQQSGFGGTGGFEDIFDTFFGGGTSRGSNRSRASRGSDLEYTLEITLEEAFFGVEKEITIPRMESCDSCDGTGSKSRSKTTCHACHGQGTIRRQQGFFAFEQTCPVCNGTGYSITDPCDACYGNGKVKKQKTLKVKIPEGVDNGDRIRLQGEGDSGSNGAMNGDLYVQIIIKEHKIFERRDINLYCEMPISFTKACLGGDIKVPTLDGEVVLKVVPETQTGKVFRLREKGMKSLRGHRRGDLLCKVVVETPVNLSAEQKELLEKFADSLGEDYQSKHAPKSKTWFDNVKDYAKKFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_VIBVY
Sequence: MANNKSAKKRAIQAEKRRQHNASRRSMMRTYMKKTVAAIAAGDKEAATAAFAVVTPILDRMATKGLIHKNKAARHKSRFAAQIKAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: UBIB_ECO5E
Sequence: MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDGKLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAFKEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGATLVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C3P1_HUMAN
Sequence: MPVRTLFPESWLWRKFTLPKSKSGISHYPISVKVPDSITTWQFVVVSLKAGQGLCVSDPFELTVMKSFFVDLKLPSSVIRNEQVQIQAMLYNFRDRQAKVRVEFPHKETLCSASKPGAPSHQAGVQIQQTSYSIVLEPQGQTQTKLVPRQEFLNMVPDTEAEVFISVQGYTQMLTHRSSDGTYHTSKGNPGSTWLTSYVFRVFALAYSMMTTQVLSLSSLCDMANWIIIDRQAEDGHFLEKGPVVMTSMQDGYQGSEEDVSLTALVLIALNEGKELCRQKNLMASIERARGFLERKLPDIQTTFAVAIASYALALANSSQANDCLDSFASPSGCGMLLNQPQSWSGEGVISNPAMCYSSLSVS
What are the official names of this protein?
Putative protein C3P1.
Protein: SLAF7_MOUSE
Sequence: MARFSTYIIFTSVLCQLTVTAASGTLKKVAGALDGSVTFTLNITEIKVDYVVWTFNTFFLAMVKKDGVTSQSSNKERIVFPDGLYSMKLSQLKKNDSGAYRAEIYSTSSQASLIQEYVLHVYKHLSRPKVTIDRQSNKNGTCVINLTCSTDQDGENVTYSWKAVGQGDNQFHDGATLSIAWRSGEKDQALTCMARNPVSNSFSTPVFPQKLCEDAATDLTSLRGILYILCFSAVLILFAVLLTIFHTTWIKKGKGCEEDKKRVDRHQEMPDLCPHLEENADYDTIPYTEKRRPEEDAPNTFYSTVQIPKVVKSPSSLPAKPLVPRSLSFENVI
What is the function of this protein?
Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family.  SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.  Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2 (PubMed:19648922).  Mediates natural killer (NK) cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (By similarity).  Positively regulates NK cell functions by a mechanism dependent on the adapter SH2D1B.  In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation.  However, in the absence of SH2D1B, inhibits NK cell function.  Acts also inhibitory in T-cells (PubMed:19151721).  May play a role in lymphocyte adhesion (By similarity).  In LPS-activated monocytes negatively regulates production of pro-inflammatory cytokines (By similarity).
What are the official names of this protein?
SLAM family member 7, Leukocyte cell-surface antigen, Novel Ly9.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GLYA_LAWIP
Sequence: MDQIILQDPELAQAIILESGRQIDKLELIASENIASTAVREAQSTILTNKYAEGYPGKRYYGGCEYVDIAENLAIERAKALFHSEYANVQPHSGSQANMGAYFALIKPRDTILGMNLSHGGHLTHGSPVNFSGRLFNIVSYGVNKETGLIDYEEVAKLAEKHKPQLIVAGASAYPRIIDFSKFRSIADTIGAKLLVDMAHIAGLVATNLHPSPIPYAHITTTTTHKTLRGPRGGMILSTEDMGKVINSQIFPGIQGGPLMHVIAAKAVALGEASKASFVTYQKQVILNAKTLAKQLLDAGFNLVSGGTDNHLLLIDLTNKKITGKDAEKALDQAGITVNKNTVPFETLSPFVTSGIRIGTPALTTRGLCEQDMIKVANWIVTALNNINNETQLKEINKEVTYFARQFPLFSW
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CID2A_ONCMY
Sequence: MVLETISRIIKIQLPAYLKKLPLPETIGGFARLTVSDWLRLLPLLGILALLGYLTIRPFLPKKKKQKDSLINLEIQKENPKVVNEIDIEDLNRTNVCYCRCWRSKTFPVCDKSHIKHNELTGDNVGPLILKKKIL
What is the function of this protein?
Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum.  Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy (By similarity).
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 2A.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family. CISD2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein.
Protein: BCS1_MOUSE
Sequence: MPFSDFVLALKDNPYFGAGFGLVGVGTALAMARKGAQLGLVAFRRHYMITLEVPARDRSYAWLLSWLTRHSTRTQHLSVETSYLQHESGRISTKFEFIPSPGNHFIWYQGKWIRVERNRDMQMVDLQTGTPWESVTFTALGTDRKVFFNILEEARALALQQEEGKTVMYTAVGSEWRTFGYPRRRRPLDSVVLQQGLADRIVKDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDSSLSDDRLNHLLSVAPQQSLVLLEDVDAAFLSRDLAVENPIKYQGLGRLTFSGLLNALDGVASTEARIVFMTTNYIDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPGQAPSLAENFAEHVLKATSEISPAQVQGYFMLYKNDPMGAVHNIESLR
What is the function of this protein?
Chaperone necessary for the assembly of mitochondrial respiratory chain complex III.  Plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex (By similarity).
What are the official names of this protein?
Mitochondrial chaperone BCS1, BCS1-like protein.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: LEXA_THIDA
Sequence: MRDLTPRQEEILNLIREWIDTTGSPPTRAEIAQHFGFSSPNAAEQHLKTLAKKGALELVSGASRGIRLPGGGGLAVVGQVAAGSPILAQENIERHVQVDTALFSPRADYLLKVRGQSMKDIGILDGDLLAVHRSAEARAGQVVVARIGDEVTVKRFQKRGHTVQLLPENADFEPIVVDLKRQELVIEGIAVGVIRSGRSL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: KCIP4_MOUSE
Sequence: MNVRRVESISAQLEEASSTGGFLYAQNNTKRSIKERLMKLLPCSAAKTSSPAIQNSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI
What is the function of this protein?
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4. 2 and KCND3/Kv4. 3 (PubMed:19109250).  Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner.
What are the official names of this protein?
Kv channel-interacting protein 4, KChIP4, A-type potassium channel modulatory protein 4, Calsenilin-like protein, Potassium channel-interacting protein 4.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm.
Protein: PHXR2_MOUSE
Sequence: MLTLQSSGTGQRKVAVHMGLLENISLKISKEVGGLYDTRMAQQGQLLKLLVGTVRKWDHSFFMDL
What are the official names of this protein?
Putative per-hexamer repeat protein 2.
Protein: RL29_RHIME
Sequence: MKAADVRALSADQLKEELAKLKKEQFNLRFQKATGQLEKSSRINEVRKDIARIKTIARQKAAEAKA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.