PharMolix/UniProtQA huggingface dataset:
Protein: COBQ_HALH5
Sequence: MKGIMVQGTASDVGKSLICTALCRIFARRGYKVTPFKSQNMSNNSYITVEGLEIGRAQGIQAEAAMEEASVYMNPILLKPRNDREAEIVCFGQAVDTVSGVKYRDGFYKRGLEAIKQALATLSQSFDMVVIEGAGSPVEVNLNDRELVNMKVAELADVPVILVADIERGGVFASLYGTLELLQPNERKRVVGIIVNKFRGDPELFSSGVQWIEQHLGVPVLGVLPHLPGVRIEGEDSLSKGQVTSVLPRDQSIDIAVLDLPYLSNYTDLEPFRYEEDVAIRFVSSVDALGRPDAIILPGTKSTFHDLQILKEKGFKERLHEYVTTDGTVVAICGGFQMLGHRLIDVAGSDTGIKGATIDGLDLAPVETRFAEKKKTVRSLGQLLHPFGTAKDIYGFEIHLGETDIVDPSIPAFLRVGNHTDGVYLHEGRLIGTYFHHLFFNDDFRSGWLNTLRRKKGLRERPTVELEKCRRASYDQLADEVERVLHVDSLLEKMERWGETS
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: GATC_DESOH
Sequence: MKITPDDIRHVAKLARLDIAETDINAFVSQIGEILDYVDTLNQVATENVEPMAHAISLTNAFREDTVREAGPVEKILNNAPAAADNMFCVPKIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: SPED_ALCBS
Sequence: MKRPWGKAVVKDPNPKITVHGFNNLTKSLSFNIFDIAYAKTEQHRQEYIEYIDELYNAERLTEILTNVTNIIGANILNVARQDYEPQGASVTMLIAEHETPPVGTDWDEEGPGPLPETVVAHLDKSHVTVHTYPESHPDNGISTFRVDVDVSTCGVISPLRALNYLIHSFDSDIVTVDYRVRGMTRDLDGTKHYIDHDINSIQNFLTEDTQNAYQMIDVNVYQENIFHTKMLLKDFDIDNYLFGAGRDEFAQTELDQIEERMKTEMLEIFYSRNLG
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: P22_ASFK5
Sequence: MLHIKMTISTLLIALIVLLIIILVVFLYHKKQQPPKKVCKVDKDCGSGEHCVRGTCSSLSCLDAVKMDKRDVKMDSKISSCKFTPNFYHFTDTAAEQEFGKTWHSIKITPSPGESHTSQEICERYCLWGTDDCTGWEYFGDEKDGTCNVYTNPYLALKYTKDHVLYLPRNHKYA
What are the official names of this protein?
Inner membrane protein p22.
What is the protein family that this protein belongs to?
Belongs to the asfivirus inner membrane protein p22 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Part of the virion inner membrane.
Protein: PSBA_HETNI
Sequence: MKNTFNTSVFANAYSFWGYVIGFILSTSNRLYIGWFGILMFPLLVLATVAFISAFIFAPPVDIDGIREPVAGALLYGNNIISGAVIPSSNAIGVHFYPVWEALGFDEWLYNGGTYQFVVLHFILGAGAYMGREWEFAFRLGMRPWIFVAFSAPLVAASAVFVVYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHILGVAAVFGGSLFSAMHGSLVTSSLLAETAGDLSLNVGYNFGQEDETYSISAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGVSTMAFNLNGLNFNQSIIDSSGHLINSWADIVNRADLGMEVMHERNAHNFPLDLA
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LPXC_SALSV
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFRPYNGFTLDFTIDFNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDDAELPLAFKAPSTVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: NTPPA_PHOLL
Sequence: MKTLYLASGSPRRRELVELLDFKFEILSPQVKEQRQEGETPRQYVSRLAKDKSLAGVAIAPEDFLVLGADTVVVLNGKVLEKPRSEQHAVAMLSALSGQSHQVITAIAISDSQRTLSDIVITDVTFRQLSTQEILDYVATGEPMDKAGAYGIQGKAGCFVKTLNGSYHSVVGLPLVETHELITKFFALVDGKGNS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAGK_STACT
Sequence: MRKRARIIYNPTSGKELFKRMLPEVLVKMEKAGFETSAYATQKAGDATIESKRALQEDYEMLIVAGGDGTLNEVVNGIAEHPKRPKIGVIPMGTVNDFGRALHLPTDILKAVDVIIEGHSVKVDIGKMNSRYFINLAAGGRITEVSYETSSKLKTFVGPFAYYIKGMEMLPQMTNVDVRIEYDGQVFQGEILLFLLGLTNSMAGFEKLVPDARLDDGYFTLIIVQKANLAELGHIMTLASRGEHIKHPKVIYEKAKSVNISSFEQMPLNVDGEYGGQLPANFLNLKQHIEVYTPKDVKNTELIQQD
What is the function of this protein?
Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid.  Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway.
What are the official names of this protein?
Diacylglycerol kinase, DAG kinase, DAGK.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
Protein: MANBB_ASPNC
Sequence: MAAFAQYTLSTGWYFKDRDELASEAWMPVPVVPSVVHQDLQANGKLKNPYVGFNELDARWVNEKSWTYRKILQKPTVLAGSRIVLAFDGLDTFAKVKLDNNIILESSNMFQAYRVDVTKALDCGDEHVLEIEFDCAMLRAQELRKQDPNHNWASFNGDPARMSVRKAQYHWGWDWGPVLMTAGIWRAVRLEVYSTRLADLWTEINLDPTHKTASISAFTELESVDLDPSYKVKFTITLHGKQIAQAEATPQEGRAKVEFNIDQPCLWWPHGYGDSTLYEVSASLNADQLELHRVTKKIGIRTAEVVQRPDKHGKSFFFRINGVDIFCGGSCWIPADNLLPNISPQRYRKWIQLMVAGRQAMIRVWGGGCYEDDSFYEACDELGVLVWQDFMFGCGNYPTWPELLKSIEQEAIYNVRRLRHHPSIVVYVGNNEDYQVQEQAGLEYNYEDKNPENWLKTNFPARYIYEELLPSVVERCSPKTFYHPGSPWGDGKITSDPTVGDMHQWNVWHGTQEKYQIFDTLGGRFNSEFGMEAFPHLSTIEYFVENEKDKYPQSHVLDFHNKADGHERRIATYLVENLRTATDLETYIYLTQVVQAETMMFGYRGWRRQWGDERHCGGALLWQLNDCWPTISWAIVDYFLRPKPAYYAVARVLNPVAVGVRREHHDWSITHAQPPKTSKYELWVVSSLQKPASGKVELRFLSVDTGREIRERIVRENVDIVPNGTTNLITDGLIDHTVDAEPHVLAARLWVDGEIVARDVDWPQPFKYLDFADRGLEVKRVSEASDQQVFQISTEKPVKCLVFEERDGVKFSDSAMDIVPGDVQTVKVTGLRADEKLKYKFLGQ
What is the function of this protein?
Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length.  Prefers mannobiose over mannotriose and has no activity against polymeric mannan.  Is also severely restricted by galactosyl substitutions at the +1 subsite (By similarity).
What are the official names of this protein?
Beta-mannosidase B, Mannanase B, Mannase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase B subfamily.
Protein: NU1C_PROMP
Sequence: MNSGLDLEYSFNEILKGFGLSSELAHIIWLPLPMLLVLVSAVVGVLVTVWLERKISAAAQQRIGPEYAGALGVLQPIADGLKLLVKEDIIPAKADSILFTAGPILVLVPVILSWLIVPFGQNLLISNVGIGIFLWIALSSIQPIGLLMSGYASNNKYSLLGGLRAAAQSISYEIPLALSVLAIVLMTNSLSTIDIVNQQSGAGILSWNIWRQPVGFIIFWICALAECERLPFDLPEAEEELVAGYQTEYAGMKFALFYLGSYINLILSALLVSILYLGGWGFPIPVEIIAKALNLPIDAPVIQVFTASIGIIMTVLKAYLLVFVAILLRWTTPRVRIDQLLDLGWKFLLPISLANLLVTAGLKLAFPQFFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: KDPC_YERP3
Sequence: MSYLRPALVLLILLTLITGIAYPLLTTGLAHLMFSQQASGSLARLGDNVVGSTLIGQNFTQPGYFTGRPSATADRPYNPMASGGSNLASSNPALGQAIGERVKLQRQANPTQLGPVPVDLVTASGSGLDPHISLAAAYYQAPRIASIRQMPLSDVQQLIDNSMQKAIPSFFGEPVVNVLNLNMALDSHSHVKVPANPAKP
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HISZ_GEOMG
Sequence: MTNPAPIEAPLPKGVTDFLPEKADKIGYIEGKIRRVFELWGFRRIITPLLEFQDVMAAGLGEDLKERTFRFDDRQTGKLLAIPSDITPQVARIVATRMRGCPLPHRLYYIGRVLRHVELQSGRSRETFQAGVELIGLDSPEADAEMVAMAVEILKGLGFEEFKVDLGHTGFIRGVMAASGLGGDARRRLQEAVGKKDSSAVRAILETEPVADRIKEELAALPRLFGGREVLAEAARVATSDSSRRALDNIAQVLDILDIHGVSDHLTLDLGEIRGLDYHSGLTFEGFVTGIGEAVCSGGRYDNLTQRYGYPAPATGFAFNILALLNALEKRPDVEASKTRDLLIFNLKDDRREALEIAQHLRALGYSTARDIIHRDFNDSLDYARRMNILRMMVIGGDYCAADEAYVVRVADKRGTAVKKADLMRNDFSLNTLP
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXAC_SOLUE
Sequence: MSFIHDDFLLSSKTARRFYHTFAEDQPILDYHCHLPPQDVAANRQFKDLFEIWLEGDHYKWRAMRANGVPESHCTGNAPAYEKFMAWAKTVPATLRNPLYHWTHLELKRYFGIDELLNEQSAARVWEQANAVLATPELTAHRILEKFHVKAVCTTDDPTDDLAAHQAIAASGLATKVFPTFRPDKALHVHAPELFNPWVDRLQVAADTHISTMAEFLDAIKKRHDFFHAMGGRLSDHGINHAFSDFPSEHEAARIFGRARCGHAATSEEHGKFAAYMMLVFGRLDAEKGWTKQLHLGARRNNSTRRFRELGADTGWDSIGDWPQADALGTYLDRLDLENALPKTVIYNLNPADNYVIATMIGNFQDGVTAGKVQFGSGWWFLDQKEAMQWQMNALSNCGMFSKFLGMLTDSRSFMSYPRHEYFRRVLCDLFGRDVENGELPDNDELIGPVIRDICYGNAQRFLGLNV
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: YQGF_STAA9
Sequence: MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_STAAC
Sequence: MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SYK_SHEB5
Sequence: MTEQVIDENKLIAERRAKLESIRPNCSANAHPNTFRRTHKAAELQAQYGQNTKEELEALGFKTSIAGRIMAKRGPFLVIQDVSGRIQAYAEKSVQADLKERFQGLDIGDIIGVTGQLHLSGKGDLYVNMEQYELLTKALRPLPADYYGLADQEMRYRQRYVDLIVNEDSRNAFIMRSKVVSAIRNFMIKKEFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEEMLSSIAIELLGSAQMPYGEHTVDFGGPYARLSMLEAIQKYNPDNATIQAMTYEQVKDVEFMRDLAKSLGMKIEKFWTCGQLLEEIFGETAEWQLMQPTFITGYPADISPLARRNDDNHFITDRFEFFIGGREVANGFSELNDAEDQDNRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVMLFTNTHTIRDVILFPAMRPQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYCCI_MICGR
Sequence: MVVWPMDRTCAWALPEQYAEFRQRATLVPAKVWDGSPTWLVSRYEHVRALLVDPRVTVDPTRQPRLSEADGDGDGFRSMLMLDPPEHTRLRRMFISAFSVRQVETMRPEIEKIVDGILDRLLALEPPVDILTHLALPMSTQVICHLLGVPYEDREFFQERSELASRPNDDRSMPALIELVEYLDGLVRTKTAHPDTGLLGTAVTERLLKGEITHQELVNNAVLLLAAGHETSANQVTLSVLTLLRHPETAAELREQPELMPNAVDELLRYHSIADGLRRAATADIVLGDHTIRAGDGLIILLSSANHDGNTFGAEATFDIHRPARHHVAFGYGPHQCLGQNLARLEMEVTLGKLFRRVPALRLAQEPDALRVRQGSPIFGIDELLVEW
What is the function of this protein?
Involved in the biosynthesis of mycinamicin, a 16-membered macrolide antibiotic.  Catalyzes hydroxylation at the C21 methyl group of mycinamicin VIII, the earliest macrolide form in the postpolyketide synthase tailoring pathway, leading to mycinamicin VII.  Uses ferredoxin MycCII in electron transfer for catalysis.
What are the official names of this protein?
Mycinamicin VIII C21 methyl hydroxylase, Cytochrome P450 MycCI, Mycinamicin biosynthesis protein CI.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: CAGA_STRGL
Sequence: MSLRHMSRRASRFGVVAVASIGLAAAAQSVAFAAPAFSVSPASGLSDGQSVSVSVSGAAAGETYYIAQCAPVGGQDACNPATATSFTTDASGAASFSFVVRKSYTGSTPEGTPVGSVDCATAACNLGAGNSGLDLGHVALTFG
What is the function of this protein?
Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic.  The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks.
What are the official names of this protein?
Antitumor antibiotic C-1027 apoprotein, C-1027-AG.
What is the protein family that this protein belongs to?
Belongs to the neocarzinostatin family.
Protein: RUVA_BORBU
Sequence: MINKIHGKVIEKKESSLVLMTTVFEFELLVSAFCLANFNLSDKVELFTYLYTRENELKLFGFLNSDEREIFKELIGVSGVGPRAALRVLSNIRYNEFKEAIDKEDIELVSKIKGIGKKMAGKMFLHLQGKLLINSELESTGLFRFKELEESIVSMGFDRKIVNSKIREAFNLAEFANLKDSEKEQFLFKEVLKRISN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SYT_PARD8
Sequence: MIKITFPDNSVREYAKGTTAMQIAESISSRLAQEVLAASVNGEVWDLSRPINDDATVKLLKWEDEEGKHAFWHSSAHLMAEALQELYPGIKFGIGPAIENGFYYDVDPGEAVIKEGDFAAIEAKMLELVAKKEEIKRQDITKADAMKMFGDRGEEYKTELISELEDGTITTYTQGSFTDLCRGPHLPNTSYLKAVKILSVAGAYWRGDEKRKQLVRLYGITFPKKKMLDEYLTLLEEAKKRDHRKIGKEMDLFMFSDTVGKGLPMWLPKGTALRLRLQEFLRRIQARYNYQEVMCPPIGNKLLYITSGHYAKYGKDSFQPIHTPEEGEEYFLKPMNCPHHCMIYKNSPRSYKDLPLRLAEFGTVCRYEQSGELHGLTRVRSFTQDDAHIFCRPDQVKQEFLNVMDIISIVFKTMNFENFEAQISLRDKVNREKYIGSDENWEKAEQAIVEACEEKGLKAKIEYGEAAFYGPKLDFMVKDAIGRRWQLGTIQVDYNLPERFQLEYTGADNQKHRPVMIHRAPFGSMERFVAVLIEHTAGKFPLWLTPEQVCIMPISEKFNDYAWQIARELGNQEIRAIVDDRNEKIGRKIRDNELKRIPYMLIVGEKEAENSEVSVRKQGEGDKGSMKIATFAALLNGEVEEMMNRWQKSND
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_SULNB
Sequence: MKNIAILCSGGDVSGMNAALKRFVEYAFDQGLTPFFVENGYEGLIDNKISKADYSDVAGIISIGGTKIRTSRSERFKEISYRQIALENLRGHGIDGLIVLGGDGSFKGMQKLSDECNDIGFIGIPSTIDNDIAGTQYCLGVDTALNAIRVAIDSIRDTASSFGRAFVIEVMGRECGYLALVSALTSGAEMCLIPEVPYNLEVYKEEFLEEKEQGRTYFIAVVSEALKNTEQIVRWFEEEIDIESRMTVLGHIQRGGIPTVHDRLMAFHFVTSAIDALREGTKSKVVCYDDGMFICKDIKDVAFKKYMIDEDLLALGREFESPQHKQV
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_CAMLR
Sequence: MNLEQIYKDCGAYLQGHFLLSSGKHSEFYLQSAKVLEDPKLAGKLCDELAKIIASYDIKFDSICSPALGGILAGYELARACNKRFIFTERVEGVMNLRRGFEVKKGEKFIVCEDIITTGGSALESAKIIESLGGEVVGFAALANRGFCAVKNLNNPRKENAKLPENLPLFALGNFEFEIYEANVCPLCEKGTKAIKPGSRGN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: Y2403_CLOTE
Sequence: MRILVDADACPGKHMIEKAASENNVEVIMYCDINHRLESSYSEIKYVESGFQSVDMVIVNEVKKGDIVISQDYGLAALVLGKGAYAINPKGYIYDNDNIDRLLFERHMSGKIRRSGGKTFNPRKRMEEDDKRLYENLIFLIGKAKK
What are the official names of this protein?
UPF0178 protein CTC_02403.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: MUTL_ECO55
Sequence: MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASQDDLEAIISLGFRGEALASISSVSRLTLTSRTAEQQEAWQAYAEGRDMNVTVKPAAHPVGTTLEVLDLFYNTPARRKFLRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGTAFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQLETPLPLDDEPQPAPRSIPENRVAAGRNHFAEPAAREPVAPRYTPAPASGSRPAAPWPNAQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLERDGNISLLSLPVAERWLRQAQLTPGEAPVCAQPLLIPLRLKVSAEEKSALEKAQSALAELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLMSEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: OLR1_MOUSE
Sequence: MTFDDKMKPANDEPDQKSCGKKPKGLHLLSSPWWFPAAMTLVILCLVLSVTLIVQWTQLRQVSDLLKQYQANLTQQDRILEGQMLAQQKAENTSQESKKELKGKIDTLTQKLNEKSKEQEELLQKNQNLQEALQRAANSSEESQRELKGKIDTITRKLDEKSKEQEELLQMIQNLQEALQRAANSSEESQRELKGKIDTLTLKLNEKSKEQEELLQKNQNLQEALQRAANFSGPCPQDWLWHKENCYLFHGPFSWEKNRQTCQSLGGQLLQINGADDLTFILQAISHTTSPFWIGLHRKKPGQPWLWENGTPLNFQFFKTRGVSLQLYSSGNCAYLQDGAVFAENCILIAFSICQKKTNHLQI
What is the function of this protein?
Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells.  OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis.  Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis.  In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation.  Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation.  Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).
What are the official names of this protein?
Oxidized low-density lipoprotein receptor 1, Ox-LDL receptor 1, Lectin-like oxidized LDL receptor 1, LOX-1, Lectin-like oxLDL receptor 1, Lectin-type oxidized LDL receptor 1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cell membrane; Single-pass type II membrane protein. Membrane raft. Secreted. Note=A secreted form also exists. Localization to membrane rafts requires palmitoylation (By similarity).
Protein: PNP_STRM5
Sequence: MAKITKTFQYGKHTVTLETGEIARQAGGAVIVKFDDTVLLVSAVAAKSAREGQDFFPLTCDYQEKFYAGGRIPGGFFKREGRATEKETLISRLIDRPIRPLFPEDYKNEVQIIATVMSLNPEIDGDIPALIGASAALSLAGTPFKGPIAAAKVGYKDGEYILNPTVSELKESQLELVVAGTANAVLMVESEAALLSEDVMLGAVTFGHREMQKVINAINELTVEAGTKPSTWEAPAKNTALISAVQEAVGPRLGEAFQVRDKLQRRDAISAIKKDVVESLAGRVAAEGWNPAELSKEFGELEYSTMRNSVLDTKVRIDGRALDTVRPIAVKTSVLPRTHGSSLFTRGETQAIVTITLGTARDGQVIDAVSGEYKENFLFHYNFPPYSVGETGRMMGPKRREIGHGRLAKRGVLAVMPSLESFPYTIRVVSEITESNGSSSMASVCGSSLALMDAGVPVKAPVAGIAMGLVKEGDRFVVLSDILGDEDHLGDMDFKVAGTAEGISALQMDIKIEGITEEIMKQALQQAKAGRLHILGEMAHGLTAPREELSDYAPRLLTIKIHPDKIREVIGKGGSTIQAITKETGTQIDIQDDGTIVIASVNAIAAQAAKARIEQITSDVEPGRIYEGKVAKIMDFGAFVTILPGKDGLVHVSQISSDRVEKVGDVLKEGDVVKVKVLEVDKQGRIRLSMKAVEEGEGASAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.