PharMolix/UniProtQA huggingface dataset:
Protein: SYA_SOLUE
Sequence: MTGHEIRQRFLDFFAERGHRVVRSSSLVPANDPTLLFTNAGMNQFKDVFLGQEKRDYVRAASSQKCVRAGGKHNDLENVGYTRRHHTFFEMLGNFSFGDYFKADAIAYAWDLITKDYGLPKEKLYVTVFREDDEAEELWQKVTGIPKSRIFRLDEKDNFWQMGETGPCGPCSEIHYDLGIEAAEPGREHEQFPDDAGGRFVEIWNLVFMQYDRDQSGKLNPLPRPSIDTGMGLERIAAILQGKITNYDTDLIYPIIEHAAEIFGVTPGADTRTDTVLRIVADHARATEFLIHDGVVPSNEGRGYVLRKIMRRALRNVRMIGIEDPFLYKLTGFVGELMKGPYPELLESIQRVARVTKDEEHRYATTFLVAERVFNDAIKSIQGNTIPGALSFKLYDTYGLALDEQEDMAREHGLAIDRESFDTEMEQQRERARASWKGAEKAAVTPAYQKLVEQGRTKFLGYSELEAASRVVGLIVDKESVQQVPAGAKAELVLDQTPFYAESGGQVGDHGILYSAAGEKVADVETAFPGVPGLTVHRIAALAPIAVGDTLRAEVAVPLRDATRRNHTATHLLHASLRTVLGKHVKQAGSIVDPGRLRFDFTHYAGLDHAELEEVERLMNQEILRNTAVQTDILPLEQAIATGAMALFGEKYGDQVRVVSVPGFSRELCGGTHVQRTGDIGVAKIVYEGSISAGVRRIEAITGEAALRQYQETSGAVKRVADMVKVSEPALIEHIEKMIANERALEKQVEQLKNKLAQAAVGSLDAEARTIKGVKVVAAHLDGMDRAQMRALADSLRNKWKSAVVVLASVEDGNVAIISAVTKDLTAKVHAGKLASSLAQAVGGKGGGRPDMAEAGGKDPSCLDEALTAVYADVESKL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTH_STAAN
Sequence: MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SEC11_YEAS8
Sequence: MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNRNTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Secretory protein 11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: ENV_HV1W2
Sequence: MRVKGIMRNCQHLWIWGTMLFGMWMICSAVEQLWVTVYYGVPVWKEATTTLFCASDAKAYSTEAHNVWATHACVPTDPNPQEVILGNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCIDKNITDWKNTTIIGGGEVKNCSFNITTSRRDKVHKEYALFYKLDVVPIKGDNNSSRYRLINCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTDNAKTIIVHLNESVEINCTRPYNNVRRSLSIGPGRAFRTREIIGIIRQAHCNISRAKWNNTLKQIVEKLREQFKNKTIVFNHSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWNGTDIKGDNKNSTLITLPCRIKQIINMWQGVGKAMYAPPIQGQIRCSSNITGLLLTRDGGNSSSREEIFRPGGGNMRDNWRSELYKYKVVRIEPLGVAPTKAKRRVVQREKRAVGTIGAMFLGFLGAAGSTMGAGSLTLTVQARQLLSGIVQQQNNLLRAIDAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTTVPWNASWSNKSMNQIWDNLTWMEWEREIDNYTSIIYSLIEESQNQQGKNEQELLELDKWASLWNWFDITNWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRVRQGYSPLSFQTHLPTPRGPDRPEGIEEEGGERDRDRSVRLVHGFLALIWDDLRSLCLFSYHRLRDLLLIVKRIVELLGRRGWEALKYWWNLLQYWSKELKNSAVGLLNAIAIAVAEGTDRVIEVVQRICRAIIHIPRRIRQGLERALL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: WSCD_ANOGA
Sequence: MALRGWRLFGVAGTILVYVGGILFLSFVSLQGPQQKRGVHGPRGYGEFETIRNRDLGLMGKKPPLQWCTELHYLDAPIRTPRKPPKLLQTFPGHFVKKFNSKPELAALVSFPGSGNTWLRYLLQQATGILTGSVYKDYGLLKSGFPAESVANSSVLVVKTHEWGPHAWAPYTKAILLIRDPERAILAEFNRQSGGHVGFASPDRYRRTKGRYWTQFVKNKLWAWEQTNLSWAKNFTGEVKLVFYDDLVENVEGTLRSILKFLNYQTDEELLACALMRKEGIYRRKKRILQFDPYSPAMHAAIDEKRAEVYAALGRYDAH
What are the official names of this protein?
WSCD family member AGAP003962.
What is the protein family that this protein belongs to?
Belongs to the WSCD family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KPYK_DICDI
Sequence: MATLSRNLRLSLDTPTSTFVRTKIVCTIGPKTMSEEALIKLIETGMNVCRLNFSHGTHDYHGQVIKNVRSAMEKTGKIIAIMLDTKGPEIRTGKIEDRCGYVDLFVGQEILVDTNMNQPGTSFRISIDYKGLLDSVKVGGYILIADGVISLSITAVEKEKGHVVCRVNNNSRLGENKNVHLPGAIVNLPAVSEKDILDIKFGVEQNVDFIAASFIRKADDVNEIREILGEKGKDIQIISKIENVEGVDNFNEILEVSDGIMVARGDLGVEVQMEKIFVAQKMIVSKCNAAGKPVITATQMLESMIKNPRPTRAEATDVANAVLDGSDCVMLSGETASGDYPYEAVDIMAKICREAELVESSTDYQTLFAALKLSSAKPVSIAETVASYAVATAIDLKADLIITLTETGLTARLVSKYRPSIPIIAVTSWSYTVKHLLATRGAIPFLVESLVGTDKLVESCLEYAMKHNLCKKGSRVVIVSGVMEGVPGKTNSLRVLTVGESIKDLKV
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: RIFK_HYPBU
Sequence: MENGAVQQLQLLGKRVKGFGVGGRYVAHPYYSGRFRELLGCTPFPGTLNFDANLDWRELASMCEPQVIPGTVWDGVRLGAVYVWKAKIMTRHGYVDCAVIRPLLSGHPPTVLEIVACEKLEPILENNPDKTVIVTIACKRGDALRWRRY
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: YQGF_FUSNN
Sequence: MKRYIALDIGDVRIGVARSDIMGIIASPLETINRKKVKSVKRIAEICKENDTNLVVVGIPKSLDGEEKRQAEKVREYIEKLKKEIENLEIIEVDERFSTVIADNILKELNKNGAIEKRKVVDKVAASIILQTYLDMKK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSM6A_ARATH
Sequence: MSGVEEKVSGTTKTPADFLKSIRGRPVVVKLNSGVDYRGTLTCLDGYMNIAMEQTEEYVNGQLKNKYGDAFIRGNNVLYISTVNMTVADGA
What is the function of this protein?
Component of LSM protein complexes, which are involved in RNA processing.  Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5'-3' mRNA decay.  The cytoplasmic LSM1-LSM7 complex regulates developmental gene expression by the decapping of specific development-related transcripts.  Component of the nuclear LSM2-LSM8 complex which is involved splicing nuclear mRNAs.  LSM2-LSM8 binds directly to the U6 small nuclear RNAs (snRNAs) and is essential for accurate splicing of selected development-related mRNAs through the stabilization of the spliceosomal U6 snRNA.  Plays a critical role in the regulation of development-related gene expression.
What are the official names of this protein?
Sm-like protein LSM6A, AtLSM6A, U6 snRNA-associated Sm-like protein LSM6A.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS10_BACLD
Sequence: MAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSVYTILRAVHKYKDSREQFEMRTHKRLIDIVNPTPQTVDALMRLDLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RF1_BORGP
Sequence: MFLEKLNSATSKIKLIEEKLQDINLIKNQKKYSKIIKEYTYLEKINTKKIEYEKILSQINDNKTILEKEDQQEMKELIKQELIDLDKKKEDLEHQIKILLLPQDENDSKNIIIEIRAGTGGEEAALFANNLYSMYIKYSERKKWKTEIINFNETELGGFKEIVFEIKGKDVFKKLKYESGVHRVQRIPITESNGRLQTSAATVAVLPNIEETEIDINEKDLRIDVYRSSGAGGQHVNTTDSAVRITHLPTGIVVQCQNERSQHKNKDQAMKILRARLYEFEDSKKQEQRSSNRKQQVGSGDRSERIRTYNFPQNRITDHRANITLYKLEEFMQGELDPLLDPLTIELQEQKFKSNNI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODC_CANGA
Sequence: MVKAVAVLRGSAGVSGVVTLEQASEQDPTTITYEIAGNDPNAERGFHIHEFGDVTNGCVSAGPHFNPFKKTHGAPQDENRHVGDLGNIKTDAQGVAKGVITDSLVKLIGPTSVVGRSVVVHAGTDDLGKGGNEESLKTGNAGPRPACGVIGLTN
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLBJ_BACSU
Sequence: MNLSKINTLLIASFFLFLTATVISHPQASFEASKTGLSMWWEVVFPSLLPFFILSELLIGFGIVRFVGVLLEPFMRPIFRVPGVGGFVLAMGMASGNPAGAKLTARLRQENQISRVEAERLASFTNSSNPLFIFGAVAVGFFQNASLGILLASAHYLGNLAVGLTMRSYGRKEEQHLRRKKTIPFPSVKDALHALHTARLAEKRPLGKILGDAVTSSVQTLLMVGGFIILFSVFNRLLSVVQLTDVLSVFTKGALTLFQLPTQLDIPLLSGMFEITLGSKLVSETDVSLLQKAIIVSFILGFSGFSVQAQVAGILSETDIRFKPFFIARLLQGVYAAVFVMLLWKPLYTAWHDPYQYVFKSLNSSDMSTAFINGWNLLVQIGPAVTLCALFTYIIIFSYRLTNGTKKG
What is the function of this protein?
Required for spore cortex formation.
What are the official names of this protein?
Sporulation integral membrane protein YlbJ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KPSS5_ECOLX
Sequence: MQGNALTVLLSGKKYLLLQGPMGPFFSDVAEWLESLGRNAVNVVFNGGDRFYCRHRQYLAYYQTPKEFPGWLRDLHRQYDFDTILCFGDCRPLHKEAKRWAKAKGIRFLAFEEGYLRPQFITVEEGGVNAYSSLPRDPDFYRKLPDMPTPHVENLKPSTMKRIGHAMWYYLMGWHYRHEFPRYRHHKSFSPWYEARCWVRAYWRKQLYKVTQRKVLPRLMNELDQRYYLAVLQVYNDSQIRNHSSYNDVRDYINEVMYSFSRKAPKESYLVIKHHPMDRGHRLYRPLIKRLSKEYGLGERILYVHDLPMPELLRHAKAVVTINSTAGISALIHNKPLKVMGNALYDIKGLTYQGHLHQFWQADFKPDMKLFKKFRGYLLVKTQVNAVYY
What are the official names of this protein?
Capsule polysaccharide export protein KpsS.
Protein: ATPB_PSEPG
Sequence: MSSGRIVQIIGAVIDVEFPRDVVPSVYNALKVQGAETTLEVQQQLGDGVVRTIAMGSTEGLKRGLDVVDTGAAISVPVGKATLGRIMDVLGNPIDEAGPIGEEERRGIHQPAPSFADQAGGNDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAMEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEKFRDEGNDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKEGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPNVIGNEHYDTARGVQYVLQRYKELKDIIAILGMDELSEDDKQLVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIAGFSGILKGDYDHLPEQAFYMVGSIDEAIEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CTNA2_HUMAN
Sequence: MTSATSPIILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGTGVQSTFTTFYEVDCDVIDGGRASQLSTHLPTCAEGAPIGSGSSDSSMLDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALSEFKAMDSF
What is the function of this protein?
May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (By similarity).  Required for proper regulation of cortical neuronal migration and neurite growth (PubMed:30013181).  It acts as negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization (PubMed:30013181).  It thereby suppresses excessive actin branching which would impair neurite growth and stability (PubMed:30013181).  Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development.  Functions in the control of startle modulation (By similarity).
What are the official names of this protein?
Catenin alpha-2, Alpha N-catenin, Alpha-catenin-related protein.
What is the protein family that this protein belongs to?
Belongs to the vinculin/alpha-catenin family.
Protein: STML2_HUMAN
Sequence: MLARAARGTGALLLRGSLLASGRAPRRASSGLPRNTVVLFVPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMVAQAMGVYGALTKAPVPGTPDSLSSGSSRDVQGTDASLDEELDRVKMS
What is the function of this protein?
Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria.  Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes.  Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress.  May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria.  Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria.  May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.
What are the official names of this protein?
Stomatin-like protein 2, mitochondrial, SLP-2, EPB72-like protein 2, Paraprotein target 7, Paratarg-7.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Mitochondrion. Mitochondrion inner membrane; Lipid-anchor. Mitochondrion intermembrane space. Membrane raft. Cytoplasm, cytoskeleton. Note=Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain (PubMed:21746876). Also associates with the actin cytoskeleton and membrane rafts in activated T-cells (PubMed:18641330, PubMed:10713127). A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells (PubMed:22623988).
Protein: RL16_ACTPJ
Sequence: MLQPKRTKFRKVHKGRNRGIAGGTEVSFGTFGLKAVGRCRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLYEMDGVSEEIARHAFALAAAKLPVKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DAPE_SHESH
Sequence: MSQDVLTLAQDLISRESVTPLDEGCQQLMADRLSAKGFDIESMVFDDTTNMWARRGNSGPLFCFAGHTDVVPVGDLNRWHTPPFDPVVIDGYLHGRGAADMKGSLAAMLVATERFVEKHPDHNGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWALVGEPSSTHKLGDIVKNGRRGSLTGNLTVNGIQGHVAYPHLADNPIHNAAPALDELARMKWDNGNEFFPPTSFQIANINGGTGASNVIPGSLEVMFNFRYSTEVTAEELIKRVLNILDAHGLDYDISWTFNGLPFLTGEGPLLDATRDAIKQVTGTDTDPQTSGGTSDGRFIAPTGAHVIELGPVNATIHKVNECVKVADLEQLALCYEVILEKLLC
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RL32_METM6
Sequence: MSEFKRLMRLKLKMKQKRPEFKRQDWFKSSRIGTSWRRPFGKHSGMRIGLTHRAAVATVGYRGPALVRGLHPSGLQDILVNNVKELVAINPEIQGARIAATVGKRKRIEIVKKANELGIRVFNVSKQKQEEFLSL
What are the official names of this protein?
50S ribosomal protein L32e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: PYRR_GEOKA
Sequence: MQKAVVMDEQAIRRALTRIAHEIIERNKGIDGCVLVGIKTRGIYLARRLAERIEQIEGASVPVGELDITLYRDDLTVKTDDHEPLVKGTNVPFPVTERNVILVDDVLFTGRTVRAAMDAVMDLGRPARIQLAVLVDRGHRELPIRADFVGKNVPTSRSELIVVELSEVDGIDQVSIHEK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: FENR_STAAE
Sequence: MKDVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMRIYPEKIIWDIGGIAPKPCHEILKDTIKQGLYFKPEVHLNERVVDIRKKAERHFEVETEAGEIYTSKAVIIAIGAGIINPKQLDVKGVERYQLTNLHYVVQSYRRFKDKDVLISGGGNTALDWAHDIAKIAKSVTVVYRKEDVSGHEAMKTLVTDLNVKLCPKTRIKYLVGNDDETHISEVVLEHVESGDRHTVKFDDVIISHGFDRCNTLLSETSSKLDMHDDCRVKGFGNTTTSIPGIYACGDIVYHDAKSHLIASAFSDGANAANLAKTYIQPDANAEGYVSSHHEVFKEANKTIVNKHLY
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: LEU1_THIDA
Sequence: MNDRLFIFDTTLRDGEQSPGASMTKDEKLRIARQLEKLGVDVIEAGFAAASPGDADAIRAIAETVRNSTVCSLARANERDIHAAGGAIKPAKSGRIHTFIATSPIHMEKKLRMQPDQVVEAAVKAVKLAREYTDDVEFSAEDAVRSDMDFLVRIFDEVIKAGAKTINVPDTVGYSIPALWGERMKALIERVPGSDKVIWSTHCHNDLGMAVANSLAAVMNGARQVECTINGLGERAGNASLEEIVMAVRTRRDVFGCDTRIDATQIVPSSKLVSTITGYPVQPNKAIVGANAFAHESGIHQDGVLKHRETYEIMRAEDVGWNANRLTLGKLSGRNAFKTKLAELGIVLDSEEALNAAFARFKDLADKKREIFDEDLQALVSDEGYATEDERFKLLSMKVCSETGEVPRAQLVFTDDGAEKQASGEGSGPVDATFKALESVVHSGADLLLYSVNNITSGTDAQGEVTVRLAQDGRVVNGQGADTDIVVASAKAYLHALNKLHSKRERAHPQV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: HCHA_ECOSM
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQEMLAAYAG
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.