PharMolix/UniProtQA huggingface dataset:
Protein: S27A1_RAT
Sequence: MRTPGAGTASVASLGLLWLLGLPWTWSAAAAFGVYVGSGGWRFLRIVCKTARRDLFGLSVLIRVRLELRRHRRAGDTIPRIFQAVAQRQPERLALVDASSGICWTFAQLDTYSNAVANLFLQLGFAPGDVVAVFLEGRPEFVGLWLGLAKAGVVAALLNVNLRREPLAFCLGTSAAKALIYGGEMAAAVAEVSEQLGKSLLKFCSGDLGPESVLPDTQLLDPMLAEAPTTPLAQAPGKGMDDRLFYIYTSGTTGLPKAAIVVHSRYYRIAAFGHHSYSMRANDVLYDCLPLYHSAGNIMGVGQCIIYGLTVVLRKKFSASRFWDDCVKYNCTVVQYIGEICRYLLRQPVRDVERRHRVRLAVGNGLRPAIWEEFTQGFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILTHVYPIRLVKVNEDTMEPLRDSQGLCIPCQPGEPGLLVGQINQQDPLRRFDGYVSDSATNKKIAHSVFRKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLLGQTDVAVYGVAVPGVEGKSGMAAIADPHNQLDPNSMYQELQKVLASYAQPIFLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGRYLPLDERVHARICAGDFSL
What is the function of this protein?
Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane (PubMed:19380575).  Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake.  May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation.  Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis.  May be involved in regulation of cholesterol metabolism.  Probably involved in fatty acid transport across the blood barrier (By similarity).
What are the official names of this protein?
Long-chain fatty acid transport protein 1, Arachidonate--CoA ligase, Fatty acid transport protein, Fatty acid transport protein 1, FATP-1, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 1, Very long-chain acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm. Note=Plasma membrane and intracellular membranes, at least in adipocytes. In adipocytes, but not myocytes, insulin via the mTORC1 signaling pathway induces a rapid translocation of SLC27A1 from intracellular compartments to the plasma membrane, paralleled by increased LCFA uptake. Insulin-dependent translocation from the cytoplasm to the cell membrane is regulated by EPRS1. Predominantly cytoplasmic in myocytes.
Protein: PYRF_BORPE
Sequence: MTFLKKLEHAWSASQSLLQVGLDPDPKRFPRELEGKPDAIFQFCRDIVDATAPYACSFKPQIAYFAAHRAEDQLEALCQHIRAQHPDLPIVLDAKRGDIGSTAENYAREAFERYQAHALTVSPYMGLDSVEPYLAWGDRGVIVLCRTSNPGGSDLQFLKMADGQPLYLHVAGLVADKWNANGQCGLVVGATFPNELAAVRQRIGDAVPLLVPGIGAQGGDINATVQAGANSAGAGMMINSSRAILYASTGEDWRQAAGEAARGLRDAINAVRT
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: K1H2_HUMAN
Sequence: MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTTCVPSPCVPRTVCVPRTVGMPCSPCPQGRY
What are the official names of this protein?
Keratin, type I cuticular Ha2, Hair keratin, type I Ha2, Keratin-32, K32.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: TRPC_PSESM
Sequence: MSVPTVLEKILARKAEEIAARRAVVSLAELEQQVANADAPRGFANALINQVRLKQPAVIAEIKKASPSKGVIRENFLPGEIARSYQAGGATCLSVLTDVDFFQGSDAYLQEARAACNLPVIRKDFMIDPYQVVEARALGADCILLIVSALDDVQMAELAAVAKGVGLDVLVEVHDGDELERALKTLDTKLVGVNNRNLHTFEVSLETTLDLLPRIPRDRTVITESGIFNRADVELMEINDVYSFLVGEAFMRAEQPGAELQRLFFPERKPAAGGPAVD
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: IF3_SYNY3
Sequence: MADKRRPQRDLPQINERIRFPEIRVIDSDGAQLGIITPNEAMEIADERGLDLVLVSETADPPVCRIMDYGKYKFEQEKKAREAKKKQHTADVKEVKMRYKIDEHDYQVRINQAKRFLKAGDKVKATVNFRGREIQHAHLAKELLDRMATDLATEADIQQAPKREGRNMMMFLSPKKV
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_PROM4
Sequence: MIILGIDPGLARVGYGLIDCNMTQKKMLDCGIIKTSQDHNDGERMVEITRDLRYLINKWKPQIASVEKFFFYRSSTTIKVVQARGVVIMTLARFRVPILEFPPMQIKLAVTGSGKANKDEVSMAVIRELDLSKPPRPDDASDALAIALTAYYQQRIVK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: AROA_SHIF8
Sequence: MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGLSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLDSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_ORITI
Sequence: MFAVIKTGSKQYRVAKDSIIKIEKIDGEPGSTIEFKEVLMIGEYSKPSFIGTPIVKGASVTAQILNQLRNQKVIVFKKKRRKNYRNKRGHKQEVTQVKIIDIAKASNC
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: XRN1_SCHPO
Sequence: MGIPKFFRWMSERYPLCSQLIENDRIPEFDNLYLDMNGILHNCTHKNDDHSSPPLPEEEMYIAIFNYIEHLFEKIKPKKLLYMAVDGCAPRAKMNQQRSRRFRTAKDAHDARLKAERNGEDFPEEQFDSNCITPGTTFMERVSRQLYYFIHKKVTNDSQWQNIEVIFSGHDCPGEGEHKIMEYIRTQKAQPSYNPNTRHCLYGLDADLIMLGLLSHDPHFCLLREEVTFGPASRNRSKELAHQKFYLLHLSLLREYLEFEFQECRSTFTFKYDLEKILDDFILLAFFVGNDFLPHLPGLHINEGALALMFSIYKKVMPSAGGYINEKGVINMARLELILLELENFEKEIFKAEVSETKNNGNSDKPSFDFLKYITESTNDIKAMTGEQKNYFLQIKKFLSSREPFIDFSANISSVDQRFLRRLCNDLHLSFSKIIKVDGTHLLRITFRDLEFNDEDEDEIEQDEIERVLQKYDNIPLLNEEQALKEKNVEKDFIQWKDDYYRSKVGFSYYDEEALKAMAERYVEGLQWVLFYYYRGCQSWGWYYNYHFAPKISDVLKGLDVKIDFKMGTPFRPFEQLMAVLPARSQALVPPCFRDLMVNSESPIIDFYPENFALDQNGKTASWEAVVIIPFIDETRLIDALASKDKFLTEEERKRNSFNAPTVFSLAEDYTSFYPSSLPSLFPDLVTRCIQKPYSLPSMEGKEYLVGLCPGVFLGAFGMVGFPSFHTLKHKAELVYHGINVFGNESRNPSVIVNVEDVKSALTSEQIAMQYVGKRIFVDWPYLREAYVESAMDESYMYLASNSTIEKRDLAEIEKSQWGRKCSHKIREYSKRFGVLFGDISLLLQVRPIKGLEYTREGALVKIFNESVLEDYPAQLVVEKIAIDDPRFTEREAPPVEVEYPPGTKAFHLGEYNYGRPAQITGCKDNKLIIWLSTAPGLDAQWGRVLVNDSKSKEKYYPSYIVAKLLNIHPLLLSKITSSFLISNGTKRENIGLNLKFDARNQKVLGFSRKSTKGWEFSNKTVALVKEYINTFPQLFNILTTHATKDNLTVKDCFPKDDTQQLAAVKHWIKEKGINSLTRVSLDEDALDSDIIKLIEEKASTIDSTYQVPKKVFGVPRYALLKPSQTRGILHSQEFALGDRVVYVQDSGKVPIAAYGTVVGIMLHHLDVVFDLPFMSGTTLDGRCSPYHGMQVEVSMVLNVTNPQFVVNTRAGKNRKTNVSANNVSQGTDSRLVTKPTSTFPSPPSPPSSSVWNKREHHPKPFSLHQVPPPESLIHKSKSKFSKGNHHSTNGTQSIRGRGGKRGKPLRSKELNRKHDHIVQPMGKLQIN
What is the function of this protein?
Multifunctional protein that exhibits several independent functions at different levels of the cellular processes (PubMed:8188690, PubMed:1637812).  5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins (By similarity).  Involved in the degradation of several hypomodified mature tRNA species and participates in the 5'-processing or the degradation of the snoRNA precursors and rRNA processing (By similarity).
What are the official names of this protein?
5'-3' exoribonuclease 1, Exonuclease 2, Exonuclease II, Exo II, p140.
What is the protein family that this protein belongs to?
Belongs to the 5'-3' exonuclease family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, P-body.
Protein: ACSA_SHEAM
Sequence: MSTQSLYSVPADIAANALVNNEQYQKMYQESVANPEGFWGEHAKRIDWIKPFTQVKDTSYDDQNLYIKWFHDGTLNASANCLDRHLASKGDDVAIIWEGDDASEQRKVTYRELHAEVCQFANALKAEGVKRGDVVTIYMPMVVEATVAMLACARIGAVHSVVFGGFSPDSIASRVIDGKSKLLITADEGVRGGRKIPLKGNIDEALNRPDVTTVETVIVLKRTGGAVNWVEGRDKWWHQVTDGAATECAVEEMGAEDPLFLLYTSGSTGNPKGVLHTTGGYLVYASMTHEYVFDYKPGEVYWCTADVGWITGHSYMVYGPLANGATILIHEGIPNFPSPARLGEIVDRHQVNILYTAPTLIRALMAEGKQHFDNFDGKSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWWQTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNEGNILEGATEGNLVLLDSWPGQMRTVYGDHERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVAHDLVAEAAVVGYPHDIKGQGIYAYVTLTKGTEATEELRQELRQWVRKEIGALATPDLIQWASGLPKTRSGKIMRRFLRKIAANEITNLGDASTLADPSVIDTLIESRLNRAD
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RUVA_CAUSK
Sequence: MIGRLRGAVAEIGEEEALIDVMGVGYVVRCGSRTLQRLPALGEEALLHIESQWSESAGLRLYGFGTREDRRAFVLLQAIQGVGPKAAMAVLDVLSPAELASAVAREDKAAVGRASGVGPKLALRIVTELKDKPITDGPVLMTAPGAVAAAPAKAAPTGDAVAALMGLGVAEVNARRVVEAAAAKLGDEATVQALIKAGLQELGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MRAY_BURL3
Sequence: MLLALAQWLQGDASFLRLFTYLTFRAVMATITALGIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLILIGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVHKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRVFDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIVLTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAYVMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIFVAETLSVMLQVSWFKYTKKRYGEGRRLLKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLTTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EI2BA_DICDI
Sequence: MTGGLNKDFDWVVAKFEEMIKRETEVSIAIPTIRILIDVIRKSNSTTVVGLQKELEDAVKQLKSCPYNQSISLSSVCDSFIRFVTKRTELDFPNFDTCKSNLVERGEQLSNKSSMSRTKISQLADKFIRDGVTILVHGFSRVVLGLLLHAAFQGKRFSVIVTESRPDSSGYKTAARLQAANIPVKLIMDGGVSRIIDKVDYVLVGAEAIVENGGIVNKIGTYQISIVAKAFKKPFYVAAESFKFTRSYPLNQSDIENLKNDHISEPFKACRSCSSCENPEQLTIDSPTLDYTPPSYITLLFTELGVLTPSAVSDELIKLYC
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit alpha, eIF-2B GDP-GTP exchange factor subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: ARGJ_PICST
Sequence: MRSVSITRTSVRFVSDKASRFVPKSGVYPQGFSVGGIHCGIKKDGKSLDLALLRNDFGKDASAAAVFTTNKFKAAPVQVSSKLIKEKKGVGINSIIINSGNANAVTGAQGMKDAEDMILVTDSVLENPVNSTLVMSTGVIGNNLPIDNILSGIPKLALNNLGSTHEHWLTCATAICTTDTFPKLVSKQFELNGHTYTLAGLAKGAGMICPNMATLLGFFVTDAPVTPSALGQILKYSVERSFNSISVDGDTSTNDTIIAIANGAAGGPVIDNNSSTAESFAVVQKEITGFAQQLAQLVVRDGEGATKFINIHVKDALSYKDAKIVASSVANSSLFKTAMFGQDANWGRILCAIGYSKVSTADSIVPTKTSVSFVPTDGSEELKLLINGEPEVVDEERASEILKSEDLDIVIDLGTGGGQSANFWTCDLTHEYVTINGDYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y303_AGRFC
Sequence: MAVDGQSNKRRKAERRGHAAEYWAALYLLLKGYRILAIRYRTRLGEIDLIARKKDLIAIIEVKARASGGSAVDAVGFHSQQRIRAAADLWLSRRRDAGRFSLRFDIVAVLPRRLPQHFIDAF
What are the official names of this protein?
UPF0102 protein Atu0303.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: MGL_ARATH
Sequence: MAHFLETQEPLVFSGKKRNDRDDEDGDALVAKKSALAVCDADPAAAIANIRHEFGEHGGVNMSIEASATFTVMEPDTMRRMFTGELGPDNDFYVYSRHFNPTVLNLSRQMAALEGTQAAYCTSSGMSAISSVMLQLCSSGGHVVAASTLYGGTHALLSHFLPRTCNITTSFVDITDHGAVANAIVEGRTQVLYFESVANPTLTVADIPELSRMAHEKGVTVVVDNTFAPMVLSPAKLGADVVVHSISKFISGGADIIAGAVCGSENLVKEMMDLRGGSLMLLGPTMNAKVAFELSERIPHLGLRMREHSHRAQVYAERMRDLGMKVIYPGLETHPQHKLFKGMVNRDYGYGGLLSIDMETEEKANKLMAYLQNATQFGFMAVSLGYYETLMSCSGSSTSSELDPSQKEAAGISPGLVRMSVGYVGTLEQKWTQFEKAFLRM
What is the function of this protein?
Catalyzes the degradation of L-methionine to alpha-ketobutyrate, methanethiol and ammonia.  Exhibits a high activity toward L-methionine, L-ethionine, L-homocysteine and seleno-L-methionine, but not L-cysteine.  Involved in an alternative cysteine biosynthesis pathway to the reverse trans-sulfuration pathway (methionine->homocysteine->cystathionine->cysteine) in which methanethiol is an intermediate.  Mediates also an alternative isoleucine biosynthesis pathway in which 2-ketobutyrate is an intermediate.
What are the official names of this protein?
Methionine gamma-lyase, AtMGL, L-methioninase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_SHEB5
Sequence: MANTLEQLKLYTTIVADTGDIEAIKRYQPEDATTNPSLILKAAQIPEYESLIDNAIDWAKSQSANLAQQLDDASDKLAVNIGVEILKLVPGRISTEVDARLSFDKEQSIAKAHKLVRLYQEAGVDKSRILIKLASTWEGICAARELEKEGINCNLTLLFSFAQARACAEAGAYLISPFVGRILDWYKKDTGKDYDAVNDPGVVSVTEIYNYYKQHGFNTVVMGASFRNIGEIIELAGCDRLTIGPSLLEELANSQIDITPKLVAATSTVAAEAPLTEAQFRWDFNQDPMAVDKLAEGIRNFAIDQGKLEVMLTAKLAN
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUI1_YEAST
Sequence: MPVSDSGFDNSSKTMKDDTIPTEDYEEITKESEMGDATKITSKIDANVIEKKDTDSENNITIAQDDEKVSWLQRVVEFFEVKNDSTDLADHKPENPIRTFKDLQESLRSTYLYNTDLRPVEAKRRTWTWKQYIFFWISGSFNVNTWQISATGLQLGLNWWQTWICIWVGYTFVAFFLILGSKVGNNYHISFPISSRVSFGIYFSIWIVINRVVMACVWNSTLAYIGSQCVQLMLKAIFGTNLNTRIKDTIKNPNLTNFEFMCFMVFWVACLPFLWFPPDKLRHIFALKSAITPFAAFGFLIWTLCKAKGHLALGSLNDNGGAISKTVLAWSVIRAIMSALDNFSTLILNAPDFTRFGKTYKSSVYSQLIALPVCYAIISLIGILSVSAAYTLYGVNYWSPLDILNRYLDNYTSGNRAGVFLISFIFAFDQLGANLSGNSIPAGTDLTALLPKFINIRRGSYICALISLAICPWDLLSSSSKFTTALAAYAVFLSAIAGVISADYFIVRKGYVNIFHCYTDKPGSYYMYNKYGTNWRAVVAYIFGIAPNFAGFLGSVGVSVPIGAMKVYYLNYFVGYLLAALSYCILVYFYPIKGIPGDAKITDRKWLEEWVEVEEFGTEREAFEEYGGVSTGYEKIRYI
What is the function of this protein?
High-affinity transport of uridine.
What are the official names of this protein?
Uridine permease.
What is the protein family that this protein belongs to?
Belongs to the purine-cytosine permease (2.A.39) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL13_UREPA
Sequence: MQKSSMLKKEVAIARRQWYLVDATDLVLGRLSVKVADILRGKNKVDYTPNVDAGDYVVVINSDKVVLTGQKALRENWYNHSHYIGGLRTRSGEEMISKYSDELIRRSVKGMLPKNKLAKQILNKLFIYKNDKHPHEAQQPTILELKLK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS3_GRABC
Sequence: MGHKVNPIGLRLGINRTWDSRWYAGGDYSRLLHDDLKLRGHLRKKLSGAGVSRVVIERPAKKPRVTIYAARPGVVIGKKGQDIEALRKGLTGMAGTDVALNIVEIRKPEIDATLVAENIAQQLERRVAFRRAMKRAVQSAMRLGAQGIRINCSGRLGGAEIARIEWYREGRVPLHTLRADIDYGVATAKTTYGTCGVKVWIFKGEILAQDPMAQDRRAAEQAPQR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ASG7_YEAS7
Sequence: MTTLASSIEHKTKHLAAPFENDENTWMKKYCCQCKSCKMSVPVQPWLPRFFVFGILCPVFWLVNLLAWWFLQYWQPHELEFHDLQEDEYPGFYEYEAITKRTVIPLKEEVLQEIRVMQNFSDSNSEEYYESKDGMPSSFLNVNTEQVEDENDTLKKYRYAFLKKVAHDVLESHDLLRKTFRNWNLRSLLGLLIDSILIIFVVLLCKKSR
What is the function of this protein?
Required for receptor inhibition of inappropriately expressed a-factor receptor (STE3) in MAT a cells.  Inhibits signaling by relocalizing the G protein beta-gamma (STE4-STE18) subunit to intracellular membranes.  May also be a mechanism for the down-regulation of the mating pheromone response after the zygotic fusion event, promoting the transition of the new diploid cell to vegetative growth (By similarity).
What are the official names of this protein?
Protein ASG7, A-specific gene 7 protein.
What are the subcellular locations of this protein?
Endomembrane system; Multi-pass membrane protein.
Protein: TLP6_PHONI
Sequence: QKKDRFLGLM
What are the official names of this protein?
Tachykinin-like peptide-VI, P.nigriventer tachykinin peptides VI, PnTkP-VI, U29-ctenitoxin-Pn1f, U29-CNTX-Pn1f.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYDND_BURPS
Sequence: MRTEYCGLVTEHLLGQTVSLCGWVHRRRDHGGVIFIDLRDREGLVQVVCDPDRAEMFAAAEGVRNEFCIQVKGLVRGRPEGTINAGLKSGRIEVLCHELNVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQHNLRLRYRVAIEARKYLDEQGFIDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQLLMVANFDRYYQITKCFRDEDLRADRQPEFTQIDCETSFLGEQEIRDLFEDMIRHIFKTTIGVELDATFPVMPYSEAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSTPANTKDGRVAALRVPKGGELTRGDIDGYTEFVRIYGAKGLAWIKVNERAKGRDGLQSPIVKNLHDASIAAILERTGAQDGDIIFFAADRAKVVNDSLGALRLKIGHSEFGKANGLVEAGWKPLWVVDFPMFEYDDEEARYVAAHHPFTSPKDEHLEYLETDPGRCLAKAYDMVLNGWEIGGGSVRIHREEVQSKVFRALKIGPEEAQAKFGFLLDALQYGAPPHGGIAFGLDRIVTMMAGADSIRDVIAFPKTQRAQCLLTQAPSPVDERQLRELHIRLRQPEQPKA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_HAES1
Sequence: MPRRRRIEPRKILPDPKFGSELLAKFINVLMVDGKKSIAESIVYGALETLSQRTGKEALEAFEIALENVRPTVEVKSRRVGGSTYQVPVEVRPTRRNALGMRWIVEAARKRGDKSMALRLANELSDASENKGAAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MUTS2_THENN
Sequence: MDYLEVLDFPKVVDLVKRHTFSDLGKRHLDTLKPTVNPWNELELVEELLNYLTRWGEPPIKGLSDITPEMEKLKAGSSLEPWELLRVSSFLEGCDILKNDLTRREYQKLKETFSQLVSFEEFVKEVNRCIEQNGEVSNRASPKLKEIRSEKRSLSTEIKKRADDFVKNHSQILQEQMYVYRDGRYLFPVKASMKRSVRGIVHHLSSSGATVFMEPEEFVELNNRMRLLEEEERLEISRILRHLTNMLLSNLKDLEKNIDLIAHFDSLYARAKFAKENNGIVVKPSSRIKLVNARHPLIPKDRVVPINLELPPNKKGVIITGPNMGGKTVTVKTVGLFTALMMSGFPLLCDEGTELKIFPKIMADIGEEQSIEQSLSTFSSHMKRIVEIVRNADSDSLVILDELGSGTDPVEGAALAIAIIEDLLEKGATLFVTTHLTPVKVFAMNHPLLLNASMEFDPETLSPTYRVLVGVPGGSHAFQIAEKLGLEKRIIENARSRLSQEEMELEGLIRSLHEKISLLEEEKRKLQKEKEEYMKLRAKYEEDYKKLRRMKIEEFDKELKELNDYIRKVKKELDQAIHVAKSGSVEEMRKTVKTLEKEREDLKKKAIEEEAEEEINVGDHVRMEGGTSVGKVVEVKGNTALVDFGFLRVKVPLGKLKKAKKKEEEDREKGTHFVSSFRTEIDIRGMTVEEAEPVVKKFIDDLVMNGIKKGYIIHGKGTGKLATGVWEILRKDRRVVSFRFGTPSEGGTGVTVVEVEV
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.