PharMolix/UniProtQA huggingface dataset:
Protein: RPOZ_CLONN
Sequence: MNNYMINPSIVDLLTKVDNRYSLVTVTSRRARQIIDGDEALVNVEDAYKPLTTAIHEVNAGKVSYESLVEGIK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SYS_AZOVD
Sequence: MLDSKLVRTQLQEIVGRLATRGFQLDVARFESLEAQRKAVQTRTEQLQAERNARSKTIGQAKSRGEDIAPLLAEVDRMGSDLEAGKRELDAIQAELDALMLSIPNLPHESVPVGADEEDNVEVRRWGVPRTFDFAIKDHVALGERHGWLDFETAAKLSGARFALMRGPIARLHRALAQFMLDLHTGEHGYEEAYTPYLVQAPALQGTGQLPKFEEDLFKISREGEADFYLIPTAEVSLTNIVAGEILDARQLPLKFVAHTPCFRSEAGASGRDTRGMIRQHQFDKVEMVRIVDPAKSYEALEELTANAEKVLQRLELPYRVLALCTGDMGFSATKTYDLEVWVPSQDKYREISSCSNCGDFQARRMQARWRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGSIRVPEVLKPYMGGIEVIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_SALTY
Sequence: MAKEFGRPQRVAQEMQKEIAIILQREIKDPRLGMMTTVSGVEMSRDLAYAKVFVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTNVVKHDEERRVNPDDSKED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_PSEPK
Sequence: MKRQLEAYCAHLRNERQVSEHTSQGYRRDLEKVIAYCEEHGIADWQALQIQQLRQLIARLHHHGQSPRSLARLLSAVRGLYRYLNREGLCQHDPANGLSAPKGERRLPKVLDTDRALQLLDGGVDDDFIARRDQAILELFYSSGLRLSELTNLDLDHLDLAAGLVQVLGKGGKARVLPVGRKAREALQAWYRLRGIGNPRDRAVFITRQGNRISPRAVRLRVKVAGERELGQHLHPHMLRHSFASHVLESSQDLRAVQEMLGHADISTTQIYTHLDFQHLAAVYDSAHPRAKRSKGTDS
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A3_HUMAN
Sequence: MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 3, H2A-clustered histone 25.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS5_XYLFM
Sequence: MAEERSQRSRDRSREEKIDDGMIEKLVAVNRVSKTVKGGRQFTFTALTIVGNGEGSVGFGYGKAREVPVAIQKSMEYARKRMANVSLNNGTLWHPVKANHGAASVFMKPASEGTGVIAGGAMRAVLEAVGVKDVLAKAIGSRNPINLVRATLKGLEDMQSPTHIALKRGKNVRDFSHGS
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: AMPA_SALNS
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMRELGMNAYLAVGHGSQNESLMSVIEYKGNPSEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMSNHNPLAHELIGASEQAGDRAWRLPLGDEFQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLSQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH34B_XENLA
Sequence: MAAQKIRSANTNGLPRCKSEGALIDFSGVPDPSLSEVKVLSPSSLRIDNPASLENVKEVVAIKDYCPNNFTTLKFSKGEHLYVLDASGGDWWYAHNTTEMGYIPSSYVQPLNYRDSCLSDSGMIDGLLESVDEGVKELDLLGDWTNSSNQDSVKKCHNNPFLRPSVSNPFLNGPLVPQTHTADTENSVDLLLFDPLAPSHAIASETSTDVLLDLLPNTSQNEVTVPVKRDNPFFRSKRSYSLSELSVLQAKSESPTTGSFFAGLKSPAPEQFQSREDFRTAWLNHRKLARSCHDLDLLGQNPGWGQTQPVETSIVCRLDSSGGAVQLPDTSISILVPEKHVASGETQQISLKALLDPPLELNNDKCTTVSPVLEIKLSNMDVQSPLTLEVRISVALGGNASALNMVGIKCLRSDAKEGPYNSVTQIYMYGDTVQVKLDNLEPVMYVVMVAQGQGIVSPSSVWEYINKKVTVGLYGPKHIHPSFKAVIVIFGHDCAPKSLLVNEVGQQANKSAPVTLQLWGKQQFVLPKPQDLQLCLFSNMTNYRVDAGDQGKMVRGFQLKLGKVSRLIFPITCQDSAQLSDFTLRVQVRDEAGGVLSQYCVQTPQPPPKTGSKSTGPRRFLKKKEVGKIVLSPLALTYKYPTFQDRPVTSLKYGKLIKTVVRQSKNPYLLEYKKGDVIGLLSEEKIRLKGQLWNKEWYIGYYQGKLGLVHAKNVLVVGKVKPSFFSGPELTTGLLLEQILRPCKFLTYIYASVRTLLMENIGSWRCFADALGYGNLPLSYFCRVELESETERVASVLEKLKEECNSEGKEKKSFQKELIMALLKIDCQGLVVRLIQDFVLLTTAVEVASRWRELAEKLARVSKQQMEGYEAPHRDRNGMLDSEAMWKPAYDFLLTWSAQIGESYRDVIQELHTGLDKMRSPITKRWKHLTGTLIFVNSLDILRAAAFSTQEPEDCII
What is the function of this protein?
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane.  Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes.  Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation.  Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).
What are the official names of this protein?
SH3 domain-binding protein 4-B.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus. Note=Specifically associated with transferrin receptor- containing clathrin-coated pits and clathrin-coated vesicles. May also localize to the nucleus (By similarity).
Protein: PYRD_BRUAB
Sequence: MSGLFETLGRRALFTFDAEQAHGLSITGLKTGIVTCRTPEDPALSVKVAGLKFPNPLGMAAGYDKNAEVPDALLKLGFGFAEVGTLTPRPQSGNPRPRIFRLVDDKAVINRLGFNNEGHEAAFKRLSRRAGKSGIVGVNIGANKDAEDRIADYVAGIRRFYLLARYFTVNISSPNTPGLRNLQAREALHELLSRVLEARDEEGNMCTLKRPVFLKIAPDLTDEELDDIAAEADAQKLDGIIVSNTTLSRSGLKNPENSNETGGLSGAPLFERSTVVLARMRERVGPDMPLIGVGGIDSAETALAKIKAGADLVQLYTGLIYRGPGLPGEILRGLSTAIKHEGVSSIAELRDRDTKEWAARKLIS
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNAJ_NEIM0
Sequence: MSNQDFYATLGVARTATDDEIKKAYRKLAMKYHPDRNPDNKEAEEKFKEVQKAYETLSDKEKRAMYDQYGHAAFEGGGQGGFGGFGGFGGAQGFDFGDIFSQMFGGGSGRAQPDYQGEDVQVGIEITLEEAAKGVKKRINIPTYEACDVCNGSGAKPGTSPETCPTCKGSGTVHIQQAIFRMQQTCPTCHGAGKHIKEPCVKCRGAGRNKAVKTVEVNIPAGIDDGQRIRLSGEGGPGMHGAPAGDLYVTVRIRAHKIFQRDGLDLHCELPISFATAALGGELEVPTLDGKVKLTVPKETQTGRRMRVKGKGVKSLRSSATGDLYCHIVVETPVNLTDRQKELLEEFERISTGLENQTPRKKSFLDKLRDLFD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1332_CITK8
Sequence: MSITAKSVYRDTGNFFRNQFVTILLVSLLCAFITVVLGHAFSPSDAQIAQLSEGDHLTGSVGLFDLVQNMTPEQQQILLRASAASTFSGLIGNAILAGGVLLMIQLISAGHRVSALRAIGASAPVLPKLFVLIFLTTLLVQIGIMLIVVPGILMAILLALAPVMLVQDKMGVFAAMRNSMRLAWSNMRLVAPAVIGWLLAKTLLLLFAPSFAALTPNVGAVLANTLSNLISAILLIYLFRLYMLIRQ
What are the official names of this protein?
UPF0259 membrane protein CKO_01332.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: USE1_HUMAN
Sequence: MAASRLELNLVRLLSRCEAMAAEKRDPDEWRLEKYVGALEDMLQALKVHASKPASEVINEYSWKVDFLKGMLQAEKLTSSSEKALANQFLAPGRVPTTARERVPATKTVHLQSRARYTSEMRSELLGTDSAEPEMDVRKRTGVAGSQPVSEKQLAAELDLVLQRHQNLQEKLAEEMLGLARSLKTNTLAAQSVIKKDNQTLSHSLKMADQNLEKLKTESERLEQHTQKSVNWLLWAMLIIVCFIFISMILFIRIMPKLK
What is the function of this protein?
SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
What are the official names of this protein?
Vesicle transport protein USE1, Putative MAPK-activating protein PM26, USE1-like protein, p31.
What is the protein family that this protein belongs to?
Belongs to the USE1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: LYSM3_ARTBC
Sequence: MVKYALLPLVAVSLVQAGGPEWHHSRTADFAVDPKVHKGCTSWINVVDASGKLTCDAFLDTINVAKRQFIFWNPQLNSDCSNIQSKASYCAFLPSHVSKQTRGQMDPPPKTKPLPPGLFNDWGNNHAQKRNDPPPKTKPLPPGLFNDWGNNGARKRDGLSPTGGLGDFHGPKEAPPPDWGHKGVVEGNHGNTMSTRSPIMGTGLPEQQSEPAFMPPHIPNLPNGMENKMVVHATTLTKKLRPTGSYVKRDANAPAPTPGSVGVAIVGCKQYHTVKAKDTCFNIAQQYPGLLFSDFLRLNPPPSNLDTVCSNLKANTRVCVKGDTKTNLVPTPSAAVGVHARDVQGWPSPTKPGTNPGCKSFELVKKGDSCEGVARKHHISVAQLKQWNPAVGPTCEKLEIGYYACVRV
What is the function of this protein?
Might have a role in sequestration of chitin oligosaccharides (breakdown products of fungal cell walls that are released during invasion and act as triggers of host immunity) to dampen host defense.
What are the official names of this protein?
LysM domain-containing protein ARB_01488.
What are the subcellular locations of this protein?
Secreted.
Protein: PCE_TACTR
Sequence: MLVNNVFSLLCFPLLMSVVRCSTLSRQRRQFVFPDEEELCSNRFTEEGTCKNVLDCRILLQKNDYNLLKESICGFEGITPKVCCPKSSHVISSTQAPPETTTTERPPKQIPPNLPEVCGIHNTTTTRIIGGREAPIGAWPWMTAVYIKQGGIRSVQCGGALVTNRHVITASHCVVNSAGTDVMPADVFSVRLGEHNLYSTDDDSNPIDFAVTSVKHHEHFVLATYLNDIAILTLNDTVTFTDRIRPICLPYRKLRYDDLAMRKPFITGWGTTAFNGPSSAVLREVQLPIWEHEACRQAYEKDLNITNVYMCAGFADGGKDACQGDSGGPMMLPVKTGEFYLIGIVSFGKKCALPGFPGVYTKVTEFLDWIAEHMV
What is the function of this protein?
This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system in limulus (PubMed:2266134).  Its active form catalyzes the conversion of coagulogen to insoluble coagulin gel (PubMed:977558, PubMed:7822328).
What are the official names of this protein?
Proclotting enzyme.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Secreted in hemolymph probably upon bacterial lipopolysaccharide (LPS) stimulation.
Protein: SELO_SALDC
Sequence: MTLSFTARWRDELPATYTALLPTPLKNARLIWYNDKLAQQLAIPASLFDATNGAGVWGGETLLPGMSPVAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGSTLDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVASDTPVQRETQETGAMLMRLAQSHMRFGHFEHFYYRREPEKVQQLADFAIRHYWPQWQDVAEKYALWFEEVAARTGRLIAEWQTVGFAHGVMNTDNMSILGLTIDYGPFGFLDDYDPGFIGNHSDHQGRYRFDNQPSVALWNLQRLAQTLTPFIEIDALNRALDRYQDALLTHYGQRMRQKLGFFTEQKDDNALLNELFSLMAREGSDYTRTFRMLSHTEQQSASSPLRDTFIDRAAFDAWFDHYRARLRTEAVDDALRQQQMQRVNPAIVLRNWLAQRAIDAAEQGDMAELHRLHEVLRQPFTDRDDDYASRPPEWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: GLYA_DESHD
Sequence: MDYIKEWILPQDPEVAEAIAQEEQRQRYKIELIASENFVSRAVMAAQGSVLTNKYAEGYPGKRYYGGCEYVDIVEDLARERVKKLFGAEHANVQPHSGAQANTAVYFAMLKPGDTVLGMNLSHGGHLTHGSPVNISGMYYNFVAYGVDQVTERIDYDVVRQLALEHRPKLIVAGASAYPRQIDFARLREIADEADSYFMVDMAHIAGLVAAGLHQNPVPYAHFVTTTTHKTLRGPRGGLILCQEEFAKAIDKAIFPGIQGGPLMHVIAAKAVAFGEALKPEFVEYQKRIVENAKVLSETLAEKGFRIVSGGTDNHLMLVDVRSKGLTGKEAEYILDEVGITVNKNTIPYDPASPMVTSGIRIGTPAVTSRGMDTLAMKKIAAAIDIALSEPNEAGAAKARDMVAALCAEYPLYPNLD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATAT_XENLA
Sequence: MEFEFDVHKIFLEPITKLDNNLIPPRRPLISSSEAQKQIMTVIDEIGKASAKAQRLPASITSASRMQANKHHLYILKDCTPKTAGRGAVIGFLKVGYKKLFILDQKGSHIEAEPLCILDFYIHESLQRHGFGKELFSFMLRNEQVDVQHLAIDRPSEKFLSFLRKHFNLWSTIPQVNNFVVFEGFFRDRKASVKKTPAKRTEGEIKPYSLTDRDFLKQEEGLPWPLSQAQINLNRASSLGSSPTRACSRPPPGEEDFVKSLRNCRPHSLQRAASSEQEDHSQRRRTSEMNLSRGLLAQKNGYSRYLSPPPPLLTQGPYAAAQIKEQQSRTDSSAQEGRTQDRPNGSNSQHQNDLISSKQHVQDLHMELAAGRTMSDLKEGQNATKSPWCDHPSYTVLGTVLNAAWVKKKQELRSTRPW
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.  May be involved in neuron development.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase 1, Alpha-TAT, Alpha-TAT1, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane, clathrin-coated pit. Cell junction, focal adhesion. Cell projection, axon. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
Protein: Y3510_METJA
Sequence: MHIHLFRCQCMIETIHIKNFRGIRELKLENLGQINIIAGKNNASKSSILEALALFLSAKEGFSLFIKILREILLWRGWYGEKSIYDLFYKNSKELEVSVKFLNQDFANLTLKNSNQSFANKNIAVELKSDKNSWSGRFDSHLIHPDYISSILTSAEATQSNFEFITSLTLIKFGYIESIYSQAYETQVLQDAIRLLREAYPEVKSLSPLQKYNKWIIHV
What are the official names of this protein?
Uncharacterized protein MJECL10.
Protein: RS20_SHEB5
Sequence: MANSKSAKKRALQSEKRRQHNASRRSMLRTYVKKVIAAIKAGDHKTAAEAFAVAQPIVDRMATKGLIHKNKAARQKARLNAKIKAIAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RL17_BIFLO
Sequence: MPTPKKGPRLASSPAHERLMLANMATSLFQNGRITTTLPKAKRLRPLAERLITFAKRGDLHSRRRVMRVIRNKSVVHILFTQIAEQMEQREGGYTRIVKIAPRVGDAAPAAVIELVTEPVAKKAVVKEAEAAAKVAEEEAPAVEAEATEAVEAPVEETAAAEAEAPAEEAADAEKAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ACCA_METNO
Sequence: MRSYLDFEKPVAELEAKLEELRALGARDGAVAISDDVSRLESKAAAALAELYATLTPWQKTQVARHPQRPHFVDYCAGLIEEFTPLAGDRSFGEDEAVVGGFGRFRGRPVCVIGQEKGATTEARIRHNFGMARPEGYRKAVRLMELAGRFGLPVLTFVDTAGAYPGIEAEERGQAEAIARSTEACLALGTPNVALVIGEGGSGGAIALATANRVLMLEHAIYSVISPEGAASILWRDAGRAQDAATAMKITAQDLLRLGVIDGIVPEPTGGAHREPEAAIRAAGDALAEALTGLADLDADALREQRAQKFLEIGRRL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_PROM3
Sequence: MNLQHTPLHDLCRDAGGRMVPFAGWDMPVQFSGLLQEHQAVRQQVGMFDISHMGVLRLEGTNPKDTLQALVPTDLNRIGPGEACYTVLLNETGGILDDLVVYDLGTNKQDSQSLLIVINAACSETDTIWLKQHLQPAGIALSDAKNNGVLLALQGPQATKVLERLSGESLASLPRFGHRQVQFYGLGAEDPSSVFIARTGYTGEDGFELLLEAEAGRALWLQLRAEGVIPCGLGSRDTLRLEAAMHLYGQDMDINTTPFEAGLGWLVHLEMPAPFMGRTALEQQAEQGPIRRLVGLKLSGRAIARHGYPLLHNNNKVGEITSGTWSPSLGEAIALGYLPTALARIGNEVAVEIRGKHHPATVVKRPFYRRPSLS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: VDTG1_BYSSP
Sequence: MNGNGTADKPGPPGGKPFGPGMGPPIQYPTGFKLYSIMTGLYLASFLTALDRTVLVVAIPQITDHFNSIDDIGWYGSAYLLTFCAFQLLFGKIYSFYNPKWVFLSAVLIFEIGSAICGAAPNSTALIIGRAIAGLGSSGIFGGSVIITFFTVPLHQRPIYTGIAGVIFALASSVGPLIGGGFTNNVSWRWCFYINLPVGALTVVTILLFLNLPPARKAGTPLREQLLQMDPLGNLCLIPGIICLLLAIQWGGSTYAWSNGRIVALLVLAGVLLIAFVGVQLWLQDKGTIPPRVMKQRSIAAGMAFTICVTAGFMSFNYYLPIWFQAIKNASSFHSGVMMLPTVISSGVASLACGFIIHRVGYYTPFMIGGSVLMAIGAGLLTTFTPTTEHPKWIGYQVLWALGCGMSMQQASLAAQTVLPKPDAPIGISLIFFSQSLGGSVFLAVDDSIYSNRLAAKLGSIPNLPQSALTNTGATNIRNLVAPQYLGRLLGGYNDALMDVFRVAVASSCACVVAAAFMEWKNVRAAKAAGPGGPGGPGGPGGPGGPEGLRGGNKV
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of viriditoxin, one of the 'classical' secondary metabolites produced by fungi and that has antibacterial activity (PubMed:31304040).  Is not essential for viriditoxin production (PubMed:31304040).
What are the official names of this protein?
MFS-type transporter VdtG, Viriditoxin biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PUR5_RHOBA
Sequence: MASTYKDAGVDLDVYAESMSRLPRLMHRTFSPRVMPSDGGFAGLFRLDFPGKLFARNYEEPVLVSGTDGVGTKLKIAQTMNQHETVGIDLVAMCVNDLICTGAEPLFFLDYVAMGRDDPARLERIVQGISDGCVDGDLALLGGETAIMPDMYGTDDYDLAGFAVGVVERKRLVDGHLIAPGDVVLGLQASGLHSNGFSLVRKIIADHGHQWSDVIDELNQDTKTPETLAQVCLRPTKIYVSAIRSIQSHYRVKQVLHGIAHITGGGIEENLDRILPPGVNAEIDPNAWTPNPIFQWLQQTGDVATSEMRRVFNMGIGMAVVVNEYYAASVASQVAKAGIECSPIGRIVEGSSKVVYKEA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1046_HERAR
Sequence: MMKNQLAGLMKQAQAMQDNMKKMQEQLALIEVEGQSGAGLVKIVMSCKNDVKRVSIDPSLLADDKDMLEDLVAAAFNDAVRKAEATSQEKMAGATAGMPMPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein HEAR1046.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DTD_STAA3
Sequence: MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNKLNFNIQQMNGEILSVSQFTLYADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVKTGEFGTHMNVSINNDGPVTIIYESQDGKIQ
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_STRPN
Sequence: MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQPREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQYEELIAAYEKQRPAYWQD
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
Putative 3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.