PharMolix/UniProtQA huggingface dataset:
Protein: DPHB_METTP
Sequence: MLFFVGLGLYDERDISVKGLEIVRCADAVYAEFYTSRLMGTSIERLEQLYGREIRMLSRSEIEGEPEWLEHARDRNVALLVGGDPMISTTHLDLRLRAIEMGIDTRVIHGSNIASAVPGITGLQNYRFGRSATVPFPHIVRGKRIVSSTPYNAVKDNLRRDLHTLLYLDIQDERFMCINEAAALLIEVANGSGDEDFASNLAVGIARAGSEDMCVRAGTLLELKTYSFGPPLHVMVIPGRLHFMEAKALRMLAGAPEELLSGYEL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: RF2_LEPBL
Sequence: MEVKSAKELKRVSKELQENFLNRWKLLNLEQDKDRLKALNEKSEDPDLWNNPEEARIVSQKKNELEKKLTPWFTIQQDILDFPDLVELTLDEKGENGIGELSMEYNRLQEKFEELELLGALKNSEDLKPAFLNIHPGAGGTESQDWAEMLLRMYIRYFEKKGYQYSLIDIQAGDGAGIKNVTLHVVGDFAFGFLKGENGIHRLVRISPFDANKRRHTSFVSVHVSPEIDDEIDIKIEEKDIRVDVYRSSGAGGQHVNTTDSAVRITHLPSGIVVACQNERSQIKNRDTAFKMLKARLYEMEQEKAKEELEKKSGEKKDIAWGSQIRSYVFHPYNLVKDHRTDHETGNVAAVMDGDIEPFILAYLKTL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_PSEE4
Sequence: MNPQRKKRLFLILGLLAGVGVAVGFALSALQQNINLFYTPTQIANGEAPLDTRIRAGGMVEKGSVQRSADSLDVRFVVTDYTKSVPITYRGILPDLFREGQGIVALGKLNADGVVVADEVLAKHDEKYMPPEVTKALKESGQAASDAGAKP
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: VSIG1_HUMAN
Sequence: MVFAFWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEPEPEPEPESEPGVVVEPLSEDEKGVVKA
What are the official names of this protein?
V-set and immunoglobulin domain-containing protein 1, Cell surface A33 antigen, Glycoprotein A34.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NTPP_PELUB
Sequence: MVKEIILASKSGVRKKILEENNIQFRVEPSNVDEDSVKESLLKEKVTPTIISKNLAELKANKISQKFTEEIVLGADSVIDLEGKIISKPNDREEALEILKRMNGKTHQLISSVCISRGGSMIWNYTDKASLTMKNMTFLELENYLKKISDKDLYAYNVYQIEGEGRNLFSKIEGDEDTIMGLPVKKIKEYLKIIK
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB28_GRATL
Sequence: MAVIQFIKGINETVVADVSLTRSRDGSKGTATFRFNNPDILKSGMEDKGDITGMYLKDDEGELMTRDVSAKFINGKPQAVEAIYIIKSPQEWDRFMRFMEKYANENKLSFTKAK
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RL14_BIFA0
Sequence: MIQQETRLHVADNTGAKELLAIRVLGGSKRRYAGIGDVIVASVKDAIPGGSVKKGDVVKAVVVRTVKERRRADGSYIKFDENAAVILGSGREPKGTRIFGPVGRELRDKRFMRIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GPDA_HALHL
Sequence: MASTIAVLGAGAWGTALASVLGRNGHAVRLWTREAEHAAAINAERVNQRHLPDCPLPDSLTATADLETALGGTDWLLIAVPSSAFRGLIERLAPYRPGKVVWATKGLESESGGFLHDVVQAGLDPAPAMAVISGPSFAAEVGQGLPTAITVAADDADLAAEVVRAFHNDRFRPYSSTDMTGVELGGAVKNVLAVATGASDGLGLGANARAALVTRGLAEISRLGAALGADPQTLIGLAGMGDLLLTCTDDQSRNRRFGFALGQGATVETALASVGSTVEGARTAAELHSLAERHSVEMPICNMVYRVVSGDTPLEQAVRELMERTPKAEFDD
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTS_ECO8A
Sequence: MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGALTSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGVLLLLVLVELRRFRQTPPQVTASDS
What is the function of this protein?
Component of an export pathway for enterobactin.
What are the official names of this protein?
Enterobactin exporter EntS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PPIH_SCHPO
Sequence: MSTEPVVFMDIAIDGRLLGRIKIRLFSSIVPKTAENFRQFCTGETLGVNQKPIGYKNSTFHRIIQGFMIQGGDFVSGDGTGSATIFNSRTFPDENFTLKHDRPGLLSMANAGKDSNGCQFFITTVPCDFLDGKHVVFGEVIEGYDIVKEIESTPVGANSRPKSNVAIVECGEM
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase cyp3, PPIase cyp3, Rotamase cyp3.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: RISB_BARHE
Sequence: MTIEICKKLHVLIVEARFYDGISDALLTGAVSTLQKAEATYDIVTVPGALEIPGAIAFAEKNSKIYYDGYVALGCVIRGETYHFEIVANDSCRALMDLTIHKHLAIGNGILTVENEKQAWARAKQDEKNKGGFAAQAALCMIALKKRFGEIIKYG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MRAY_SYMTH
Sequence: MEQTTLLRLAGAGLTALAGALALGPVVIPLMRRLRAGQTIRAEMSARHQAKAGTPTMGGVIFIIPAILATLIFAPRSGDALPRLIIALVLTVGHGLVGFADDYIKVVLKRSLGLRARDKLLAQVGLAAVLGYGAVEVLGLGTAVTLPVLNLTLELGRPLYYLLVLIMVWGTASAVNFADGLDGLLGGLSVITFSFYGLVVALALGQTDMAVLGTALVGGVLGFLHYNRHPARIFMGDVGSFALGGALAALAVLTKTEFLLVIVGAVYVIEVISVILQVLSFRLTGRRIFKMAPLHHHFELLGWSEGQVLRLFWGAGLLFTLLGWLVLPGMLAGR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: I1B2_CONCL
Sequence: MKMSVTFLLILMILPLFTGEWQSGSRLSALKKRLLEKRLLQKRFCTEIGKDCGTSWECCEDCCIHGTCSHESNCANFKLR
What are the official names of this protein?
Conotoxin Cl11.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LCA10_HUMAN
Sequence: MSSCPVHDCPSWDPERLEPVETGSRGALRLRGGAPGSAAGFRASIWGPAGYPSPVGLGHPASLPRPAYSPRCPEPDARHGWGSGSNAGYRGPDRAGRTPCPAQDREGRSSSPVPPPRLKAMTSQARKQNGGALIDTVDWTREAPDSDPVMSMQKTQKPQTTVGQ
What are the official names of this protein?
Putative lung carcinoma-associated protein 10.
Protein: APOF_RAT
Sequence: MGAQLLTCTVSDSIRHQFSCFATSCCVLWVPKGVSTMLPPSQLGSQPPTSDPLSCQALLPRSLPGFTHMPPLSKFLVGLALRNALEEAGCWADVWALQLQLYRFGGVEATQALIRHLQELQKGGRADWKVSVNALSSALQLLAWEQAGPKRVKRSLSNMGCENEQEQRVHNVVELLPAVGTYYNLGTALYYAIKNCTDKAKERGRDGAIDLGYDLLMTMVGMSGGPTGAVITAALKPALKAGVQRLIRYYHDEEGVTTSQPETRKDAPTYRDDVEETTMSNLVSEVESTTSNWGRPLLKNYVFLAYKR
What is the function of this protein?
Minor apolipoprotein that associates with LDL.  Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport.  Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
What are the official names of this protein?
Apolipoprotein F, Apo-F, Liver regeneration-related protein LRRG151.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein F family.
What are the subcellular locations of this protein?
Secreted.
Protein: UGPE_SALCH
Sequence: MIENRRGLTIFSHTMLILGIAVILFPLYVAFVAATLDDRAVFETPMTLLPGTQLLENIKTIWVNGVGVNSAPFWLMMLNSFIMAFSITVGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFMTLPDELVEAARIDGASPMRFFRDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVNLGTAVAGIKGMIATGEGTTQWNQVMAAMLLTLIPPVVIVLAMQRAFVRGLVDSEK
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
sn-glycerol-3-phosphate transport system permease protein UgpE.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SEM6B_HUMAN
Sequence: MQTPRASPPRPALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSEDRAGLVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRLGERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSGLLPTPEQTPLPQKRLPTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTPDGRLYAARPGRASHGDFPLTPHASPDRRRVVSAPTGPLDPASAADGLPRPWSPPPTGSLRRPLGPHAPPAATLRRTHTFNSGEARPGDRHRGCHARPGTDLAHLLPYGGADRTAPPVP
What is the function of this protein?
(Microbial infection) Acts as a receptor for P. sordellii toxin TcsL in the in the vascular endothelium.
What are the official names of this protein?
Semaphorin-6B, Semaphorin-Z, Sema Z.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RNH2_STRGC
Sequence: MATIKEIQQRLELVTELSDSFLEEVAKDQRSGVQKAVEKRKKAIQAELDEDLRLDQMIRYEKELYQSGYQAIAGIDEVGRGPLAGPVVAAAVILPPGCKIKGLNDSKKIPKKKHQEIYQAVMDKALAVGIGLMDSDIIDKVNIYEATKLAMKEALSKLPLKPDYLLIDAMKLDVEIPQESIIKGDANSLSIAAASIVAKVTRDRLMADYDKEFPGYAFAQNAGYGTKRHLEGLEHYGVSPIHRKTFEPVKSMLG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_LEPBA
Sequence: MSYTPSSNDLIAISPMLILCGVALLSLVVQFLIPEEDEGKPLWVLSILGILVAMYALYHTTNSPGYGKFFGSQISISPLTVWLSAIYLIAGLITLLVAPPFLSQHKTLFPEFFPLMLFCLSGMMFLTSGYDLIVIFVGLEILSLSLYVMIGMARTSVSALESAMKYFLLGTFSSGFMLLGIAFLYGGSGTTNLDGALRGLSLKGYEANFSKLGLGLFFVGVSFKAALVPFHSWTPDVYEGAQTPITGFMASAGKASALGLVIILFNHIPMGEMGNVWKYLMGTIALISMTWGNIVALKQDNLKRMLAYSSISHAGYIVAGIACGAGLEALYYLFSYSLLNLAAFAIISYLEQGKHEVTVNGISHLSGEHPFTALALSLVFLSFAGFPPLIGFWTKLFLLQKMAESDLFFHRVLLFGAVANSCIAFYYYMKITIQSYMKQETGVVAGARDLPSLPTLGFLIFLLCVFFTAGWIFFQPGSLL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AN32B_MOUSE
Sequence: MDMKRRIHLELRNRTPAAVRELVLDNCKAMDGKIEGLTDEFVNLEFLSLISVGLFSVSDLPKLPKLKKLELSENRIFGGLDRLAEELPSLTHLNLSGNNLKDISTLEPLKRLDCLKSLDLFGCEVTNRSDYRETVFRLLPQLSYLDGYDREDQEAPDSDVEVDSVEEAPDSDGEVDGVDKEEEDEEGEDEEEEEDEDGEEEEDEDEEDEDEDEDVEGEDDEDEVSGEEEEFGHDGEVDEDEEDEDEDEDEEEEESGKGEKRKRETDDEGEDD
What is the function of this protein?
Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription (PubMed:21636789).  Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle.  As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis (By similarity).  Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes (By similarity).  Also plays an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1 (By similarity).  Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (PubMed:30890743).
What are the official names of this protein?
Acidic leucine-rich nuclear phosphoprotein 32 family member B, Proliferation-related acidic leucine-rich protein PAL31.
What is the protein family that this protein belongs to?
Belongs to the ANP32 family.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates in the nuclei at the S phase.
Protein: GLYA_CLOB6
Sequence: MDFTNLKNTDPELLDMIKKEEERQEYNIELIASENFTSLSVMEAMGSLLTNKYAEGYPHKRYYGGCEFVDEVEDLARERLKKLFAAEHANVQPHSGSQANMAVYMSVLQTGDTILGMDLSHGGHLTHGSPVNFSGKLYNFISYGVDKETETIDYEQLKKIALENRPKMIVSGASAYPRIIDFQKIREICDEIDAYMMVDMAHIAGLVATGLHPSPVPYADFVTTTTHKTLRGPRGGAILCKEKYAKAVDKAIFPGIQGGPLMHTIAAKAVCFGEALREDYKEYMQQVVKNTKVLGEELKNYGFRLISGGTDNHLLLIDLTNKNITGKDAEKLLDSVGITVNKNTIPFETLSPFITSGIRIGTPAVTTRGFKEEEMKKIAYFMNYSIEHREENLSQIKEQIKEICKKYPLHQNA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_PSE14
Sequence: MPSLYLASGSPRRRELLTQIGVSFTVLNAQIDETPFDHETPAAYVERLALGKAQAGLSVLAAEQQACVMGADTAVVLDGRILGKPADEADALAMLTALSGREHEVMTAVALSDRHRSETRIVTSRVRFRPIQPHEAQAYWASGEPADKAGGYAIQGLAAIFVEGLQGSYSGVVGLPLCETAELLGHFGIPCWQCLEGDES
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_XANCB
Sequence: MATTLNPSEISDLIKTRIEAVKLSAESRNEGSVTSVSDGIVRIFGLADVMQGEMIELPNNTFALALNLERDSVGAVVLGDYENLREGDVAKTTGRILEVPVGPELLGRVVNALGEPIDGKGPLGATQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPIGRGQRELVIGDRQTGKTALAIDAVINQKGTGIKCVYVAIGQKASTVANIVRKLEENGALAHTVVVAATASESAAMQYISPYAGCTMGEYFMDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRISLAQYRELAAFAQFASDLDEATRKQLERGQRVTELMKQKQYAPMSIANQALSIYAVNEGYLDEVPVNKLLAFEEGLHAHFANTQGELVSKINTTGGWDNDIEAAFKKGIEEFKTTGSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HYBF_ECOL6
Sequence: MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAVRFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPICHGERLRVDTGDSLIVKSIEVE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HybF.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family. HybF subfamily.
Protein: PFF1_YEAS2
Sequence: MKLKSVFRSVLKYRKTNLSLLLLITYSIITLLYIFDHERYKLNLPKEDEHPEFNDLLETAWGDLQIITASFHPYTSKENDKVHDYLLKRVLEITGNSSFASVSDDKESERSILFQQQDPFNESSRFSRVTYFESSNILVKLEGKNPEEEGLLLSAHFDSVPTGYGATDDGMGVVSLLANLKYHIKHRPNRTLIFNFNNNEEFGLLGASTYFNHSWSNLTKYVINLEGTGAGGKAVLFRTSDTSTAKIYQQSVKENPFGNSIYQQGFYSRYVRSETDYKIYEENGMRGWDVAFYKPRNLYHTIKDSIQYTSKASLWHMLHTSLQLSAYVASNSLDTADQTPACYFDFIGLKFFVISAKTLFYWNCIFLLVSPVVAIGLYLISRDRMTWKSHSWLSWTRFPLSLAAGIIVQKLFSNDIIRSNPLTFSRNYFWPISAFFTQVIFTSYVLINCSNFFFPCADMKSLSIIELFIILWTILLFTSKLLYSSDYRYTGLYPLSIFFLLSTIAAILRLLALALGMRTRKRLGRECRDHHSNYSSHSQIDMERDGQENLEQPQDQFTSSQDDQASIQDDNVSTTSAGPSHNVDEDHGMDSSSQQHDERVPLLKGSNSMEEGLSTRENSLKLEYTDYAWIIQFLLIVPIPSFILFNSVDVIMDALNHTVQEGSKATFDVLRFGMVGSILIALPILPFFYKVNYITISLTALLFLISASKTLLVHPFTNSNPLKVRFSQNIDLSQGNAASVHVLGREGNFLKPMLQDLPSIKYSSTHINCTSVTNGMELCMYDGMQPNLLSTNGNTNISSMVKVHVLHNNRNSTERSPYEPIVAELLLEVKENRACTLTFESRHQAKSPVREITVYQKKNSAPQKANITKTIKSASGINELQLHKLDFDKETYHIGVQWFPKLLTDGNVEDDKLGTKDELSVSISCYWGEYDSESVVNGTAVRKIPAFDELINYAPLSFSFTNEQKGLVIVKDAIIL
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: ULAG_ECOLI
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.  Also shows phosphodiesterase activity, hydrolyzing phosphodiester bond in the artificial chromogenic substrate bis-p-nitrophenyl phosphate (bis-pNPP).
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBED_SALHS
Sequence: MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYSPTVKPSSKGNYHSVSITINATHIEQVETLYEELGNIDIVRMVL
What are the official names of this protein?
UPF0250 protein YbeD.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: LACR_LACLL
Sequence: MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALEADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPGTTLVQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMASTNLKAMRFAKAFVRANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYDFFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD
What is the function of this protein?
Repressor of the lactose catabolism operon.  Galactose-6-phosphate is the inducer.
What are the official names of this protein?
Lactose phosphotransferase system repressor.
Protein: YQGF_XANOP
Sequence: MPEAGAILPDGTVLGFDVGSRRIGVAVGTALGAGARAVAVINVHASGPDWDALDRVHKEWRPDGLVVGDPLTLDDKHQPARKRAHAFARQLRERYALPVVLIDERSSSVEAAQRFARERADGRKRRRDAEALDAMAAAVIVERWLAAPDQATLLP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAGE1_RAT
Sequence: MSETETMNVNGPQDFYSDSPFCLEASFSSSDLLQNETKNVKRGNESVHMSSEDILSTEGSLLGDINLGNYPERIQNQPANTRVSSSRQFEPICKFHWIDAFNDDSSVPDLTRAFSYSEEKPELQSQVYNDPADASQKPDPLKEESLMESSTSENKDELVHEPVRKSRSLCLNHYRGKTRPLTETPLVRSVVVDVALNNNQPESFLGKENVCRNGENLSDSENCFDQLDLRAIYKAGKPEVSSKGIQNSGEFSDMSVGPQEEVTEDGLDSLAITSPWSPAGIFKGRRSQDDFQMPDGELDFESLEPLEEDMALNEALQKLKQTNKKQELQIQDLHGRNLTLESRVQELQTKVSKQHVLLDIINKLKVNVEELIDDKYNVILEKNDINKKLQDLQETSANTKKHLQESKKDQESLQLQVKKIKVHYVRLQERYIAEIQQKNRSVTQCLEIEKTLSKKDEELQRLQRHKGELEKATSSALDLLKREKEIREQEFLSFQEEFQRREKENLKERRKLKSRVEKLVAQVKSLLFTCESERAQTTALQQQVDALRLENLELRQQAAKREAQACTPSFEIIQPKEKLEEVVEPDVTQDTKGTHCNLFLNCSSCKENPELPSMKRTSPLTSRLHSLLALTIGLLTCQDLAIPDTELRQESKKANDIMLQRLKDCQLRKKDLDKELLKHRNRIATLKELIANEKALQDHTMEITDFDTEEVKNASEAPVLLTVKLDKYHSLNEELDFLITKLGDLLESKEDHYSRLIEENDKYRRHVGSLINKVTSYEEIIKCADQRLEISHSQIAHLEERNRHLEDLIRMPREKARGLRPRLDNHPKSMTLISHLEGHHKECSISM
What are the official names of this protein?
Cancer-associated gene 1 protein homolog, CAGE-1, Cancer/testis antigen 3 homolog, CT3 homolog.