PharMolix/UniProtQA huggingface dataset:
Protein: DAPAL_PYRHO
Sequence: MEGVIVPLITPFKEDHSIDFEALEWLIKFLEEKGVHGIFINSTTGEFTSLSLEERKILAEKGREVTSRTYLVGTGSTSTFEVIELTKHAKEIGADGVVIVSPYYCRLKEDAIFKHFSMVAEKVDIPIILYAIPSCANPISLEVVRKLALEYSNVIGVKASVDSLTYLSGLIEIKEERKDFKVFTGLDQYFLPNLILGGDGGIMACANFVPEIHLEVWNAFKKGNLEKAMNSARKLVKITKIYSIASSFASAVKLAMVARGFPIKPILRPPYMMDGEEVFKKIKEIVS
What are the official names of this protein?
Uncharacterized DapA-like lyase PH0847.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_PECAS
Sequence: MHKHRKPTEADVTPESLFYQRRRVLKALGISAAALSLPLSAQADLLAWFKGSDKPKAPPGKPLTFSQPTDWKLDLPLTPEDKVTGYNNFYEFGLDKADPAANAGGLKTDGWTIKIDGDVAKPLTLDIDDLLKRFPLEERIYRFRCVEAWSMVIPWVGFELAKLIKFAEPTSNARYVAFQTLHDPEQMPGQKDRFMGGGLDYPYVEGLRMDEAMNPLALLAVGVYGKTLPPQNGAPIRLVTPWKYGFKNIKSIVHIRLTRERPPCTWNLAAPDEYGFYANVNPHVDHPRWSQATERVIGSGGLLNVERQPTLLFNGYAEQVASLYRGLNLRDNF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: BCHL_RHOP5
Sequence: MNILTDPTKLQGCTDTNANKCVEGDGEGSVQVQLDPDLKIGTAKVFSIYGKGGIGKSTTSSNLSVAFSKLGKRVLQIGCDPKHDSTFTLTKCLIPTVIDVLESVNFHAEELRPEDFVFEGYNGVMCLEAGGPPAGTGCGGYVVGQTVKLLKEHHLLEDTDVVIFDVLGDVVCGGFAAPLQHSDRAMIVTANDFDSIFAANRIVAAITAKAKNYGVRVGGIIANRSDATDQIDKFSERTGVPRVAHFPALDIIRKSRLKKSTLFELDHSPELAKVQEEYMRLATELWEGKQPPCEGKALKDREIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: CUSF_ECOLI
Sequence: MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKGIDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSLLQDIKVSQ
What is the function of this protein?
Part of a cation efflux system that mediates resistance to copper and silver.  Binds one copper per polypeptide (PubMed:11399769, PubMed:24917681).
What are the official names of this protein?
Cation efflux system protein CusF.
What are the subcellular locations of this protein?
Periplasm.
Protein: SSN8_CHAGB
Sequence: MAANYWESTQRKHWQFTKQDLAAIRQRLDDEDPGLVQMFPLPQLRHLNIYFNQQINRLSKRIGLRQQVMATAQVYLKRFYTRIAIRQTNPYLVLTTVLYLACKMEECPQHIRMMTQEARSLWPSDLHGHDPARVGECEFSLISEMHSNLIVHQPYRSLLGVQDEFGLTQDEMSLAWTVINDHYMTDLPLLHPPHVVALTAVLLALVLRPSANTPAAGGAGGNAGAAAAAAAAGAGGVAMAATALAQAQAQVQARAAAIAAAGAGGGTPGFGSQGSQQQAGFSQGNSQGSLQGDSAAAEPKKVTDPRLAKVQRFAAWLADSNIDIEAMVDCTQELISFYECHEQYNDKHTKEQISRFIKARNLDK
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
RNA polymerase II holoenzyme cyclin-like subunit.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGB_METS4
Sequence: MSQSETDALPNVHVRAEVLVQALPHMQRYDEEIVVIKYGGHAMGDRAAAEDFAEDVVLLEQSGLKPVIVHGGGPQIGRMLDRLGIKSEFREGLRVTDAATVEVVEMVLAGSINKQIVGWISAEGGKAIGLCGKDGNMVQARRATRTVVDPDSNLEREVDLGLVGEPERVNRAVLDAVLKAELIPVLAPVAVGSDGQTYNVNADTFAGAIAGALRAKRLLLLTDVPGVLDKNKKLIPELSVEDCRRLVADGTITGGMIPKIETCIYAIEQGVEAVVILDGKVPHAVLLELFTDYGAGTLIRRSAP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_PYRCJ
Sequence: MHFPLPQPDVSATFKRRLNRFLGVAEVEGEEALVHIHDPGRLAELLFPGSTVWLRKKAGGKAPYYLLAVELPEELVLVDSAMHNKIATWLVEEGHVFKGYSVAKTEPSYGRGRFDLLLRRPDGGLALVEVKGVTLEVGGVALFPDAPTARGARHMEELARAAAEGYEAHVLFLVLRRRARLFSPNWALDAKFAEALAKAADAGVKISAVKLEMFKWGLKFAGELPVKLR
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: FETP_VIBVU
Sequence: MSRTVFCARLNKEADGLDFQLYPGELGKRIFDNISKEAWGQWQHKQTMLINEKKLNMMDPEHRKLLETEMVNFLFEGKEVHIEGYTPPSK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: NFUA_HAEI8
Sequence: MEQATQQIAISDAAQAHFRKLLDTQEEGTNIRIFVVNPGTPNAECGVSYCPPNAVEESDIEMKYNTFSAFIDEVSLPFLEEAEIDYVTEELGAQLTLKAPNAKMRKVADDAPLIERVEYVIQTQINPQLANHGGRITLIEITEDGYAVLQFGGGCNGCSMVDVTLKDGVEKQLVSLFPNELKGAKDITEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: RL6_PSEA8
Sequence: MSRVAKNPVKLPAGVEIKLAGQQLSIKGAKGALELKVHPSVEVIQDSGELRFAARNGDQQTRAMAGTTRALVNNMVVGVSQGFERKLQLVGVGYKAQAKGQVLSLSLGFSHPVDYELPAGIVAETPSQTDILIKGIDKQLVGQVAAEIRDFRPPEPYKGKGVRYADEVVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: LPXD_PSET1
Sequence: MQNYTLSQIAELLSAELQGDGALEITKIATLAHARSGHIAFLANKKYRSQLEVTQASAVIVSEADAPYFNGNKLIVANPYVSYAKLAQLMDTTPRSAATGIHPSAVVHPNATVSKSAAIGANTVIESNAIINDNVQIGPNSFIGEGVKIGSGTKLWSNVTIYHNVEIGSDCLLQANSVIGSDGFGYANERGQWIKIPQLGSVIIGDKVEIGASTTIDRGALDDTIIHSNVIIDNQCQIAHNVEVNSGTAIAGCTVLAGSVTIGKNCQIGGMTAINGHMSVCDGVIITGMSMVTKSITEPGIYSSGIPHTTNKEWRKSIAHLRNLSEMKSRIKALEQLNKP
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: GFOD2_BOVIN
Sequence: MKMLPGVGVFGTGSSARVLVPLLRAEGFTVQALWGKTEEEAKQLAEEMNIAFYTSRTDDVLLHQDVDLVCINMPPPLTRQISVKALGIGKNVVCEKAATSVDAFRMVTASRYYPQLMSLVGNVLRFLPAFVRMKQLIAEHYVGAVMICDARVYSGSLLSPNYGWICDELMGGGGLHTMGTYIVDLLTHLTGQRAEKVHGLLKTFVRQNAAIRGIRHVTSDDFCFFQMLMGGGVCSTVTLNFNMPGAFVHEVMVVGSAGRLVARGADLYGQKNSAPQEELLLRDSLAVGAGLPEQGAQDVPLLYLKGMVYMVQALRQSFQGQGDRRTWDHTPVSMAASFEDGLYMQSVVDAIKRSSRSGEWEAVEVLAEEPDANQNLCEALQRNNL
What is the function of this protein?
Promotes matrix assembly.
What are the official names of this protein?
Glucose-fructose oxidoreductase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: BIP2_TOBAC
Sequence: KVQQLLKDYFDGKEPNKGVNPDEAVAFGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRLLGKFDLTGIAPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNDKGRLSQEEIERMVREAEEFAEEDKKVKERIDARNSLETYVYNMKNQINDKDKLADKLESDEKEKIETATKEALEWLDDNQSAEKEDYEEKLKEVEAVCNPIITAVYQRSGGAPGGGSSEEEEEEDGHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
What are the official names of this protein?
Luminal-binding protein 2, BiP 2, 78 kDa glucose-regulated protein homolog 2, GRP-78-2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RL7A2_ORYSJ
Sequence: MAPKRGGRAPVPAKKKTEKVTNPLFEKRPKQFGIGGALPPKKDLHRFVKWPKVVRIQRQRRILKQRLKVPPALNQFTRTLDKNLATNLFKMLLKYRPEDKAAKKERLLKRAQAEAEGKTVEAKKPIVVKYGLNHVTYLIEQSKAQLVVIAHDVDPIELVVWLPALCRKMEVPYCIVKGKARLGSIVHKKTASVLCLTTVKNEDKLEFSKILEAIKANFNDKFDEVRKKWGGGVMGSKSQAKTKAREKLLAKEAAQRMT
What are the official names of this protein?
60S ribosomal protein L7a-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: HIS6_AZOBR
Sequence: MLKMRVIPCLDVKDGRVVKGVNFVDLIDAGDPVEQARVYDREGADELTFLDITASHENRDTIYDVVRRTAEQVFMPLTVGGGVRTVDDIRKLLLAGADKVSINTAAIHRPEFVQEAAEKFGAQCIVVAIDAKQVEPGRWEIFTHGGRKATGIDAIEWAKRMESYGAGEILLTSMDRDGTKSGFDLALTRKVADGLRIPVIASGGVGTLDHLVEGIREGHATAVLAASIFHFGTYTIGQAKAALAEAGIPVRPARMAEAAHG
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_BIFLO
Sequence: MIQQETRLHVADNTGAKELLAIRVLGGSKRRYAGIGDVIVASVKDAIPGGSVKKGDVVKAVVVRTVKESRRADGSYIKFDENAAVILGSGREPKGTRIFGPVGRELREHKFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MCCB_ARATH
Sequence: MLRILGRRVVSASKELTSIQQWRIRPGTDSRPDPFRTFRGLQKGFCVGILPDGVDRNSEAFSSNSIAMEGILSELRSHIKKVLAGGGEEAVKRNRSRNKLLPRERIDRLLDPGSSFLELSQLAGHELYEEPLPSGGIITGIGPIHGRICMFMANDPTVKGGTYYPITIKKHLRAQEIAARCRLPCIYLVDSGGAYLPKQAEVFPDKENFGRVFYNESVMSSDGIPQIAIVLGSCTAGGAYIPAMADESVMVKGNGTIFLAGPPLVKAATGEEVSAEDLGGATVHCTVSGVSDYFAQDELHGLAIGRNIVKNLHMAAKQGMEGTFGSKNLVYKEPLYDINELRSIAPVDHKQQFDVRSIIARIVDGSEFDEFKKQYGTTLVTGFARIYGQTVGIIGNNGILFNESALKGAHFIELCSQRKIPLVFLQNITGFMVGSRAEANGIAKAGAKMVMAVSCAKVPKITIITGASFGAGNYAMCGRAYSPDFMFIWPNARIGIMGGAQAAGVLTQIERATKKRQGIKWTEEEEEAFKKKTVDAYEREANPYYSTARLWDDGVIDPCDTRKVLGLCLSAALNRPLEDTRFGVFRM
What is the function of this protein?
Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.
What are the official names of this protein?
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, MCCase subunit beta, 3-methylcrotonyl-CoA carboxylase 2, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RIMP_HELPJ
Sequence: MTKKIEEKIEGVIESLGYLLYDVSLVKENEQHVLRVSLKNPNGAVSLDICQQVSEIISPLLDVCDFIQDAYILEVSSMGLERTLKTPKHFKLSLGEKVEVKLINKESFQAVLKDANDLSADFELDNHAIKSVEYKDLKKVKTLFEW
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_CHLP8
Sequence: MSNRLISGSTVALVTPFKEDGSVDYEALRRLVRFHREAGTDIILPCGTTGESPTLTNEEEAEIIRTVRDEAGDSMMVAAGAGTNDTRHAVELSRNAEKAGAQAILSVAPYYNKPSQEGYYQHFRHVAESVSVPIIIYNVPGRTASNVSAETILRLAHDFDNVLAVKEASANFEQIMTLIDERPERFSVMTGEDGLMLPFMALGGDGVISVAANQVPKVVKGLIDAMKAGNLEEARAINRKYRKLFRLNFIDSNPVPVKYALSLMGMVEEAYRLPLVPMSDADKATMKAELEQLGLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA_ISAV8
Sequence: MDNLRECINRKRRLLALPDVPETSDAFLSDLRHLYMCVAFCDQHKTTGDESRFTNLELLDQDEALGAQRAFEAKHGIKGGSLGDVLDHELKKVIEFTFTSGSLYIAEQRKRKTQADSIIVCVSEGLNDFSVSHGVLDMGLVETGVNAVRDFCTQNGIPMKINQVGSTRTPTPISTCKISEQITRQINSTITERKMETVLAAIAIKPELKXTQKGCXXCKELEDENILWMDPQFCEIDESFPYRGGPYGNFLQELLLTTNDVETNGKDREEVVKXILDNKAFTVESGECIITLPDKMTCFGEQEKKRPATIDEVRTAGERFEQSVKPKTQRYGRLSDKWMELEKFIFTASKTEVDTFLSVGTERLESVGVCVGALHRATTTRIIRPMIQGGKCWGMMFKTKSKMGDTRKEGYCHAIIFGKGEDKSGQNKMTMMGKTVHWHLRVVKSKGDWMAQQLCANKSRIWQHDPELVTEGVTVLMTPFSQKIATISRWRAMRLDSMFHVSSAWHHSPACEAASAMLRKFVEIVHAINQKRDWGVVGSMEDMVKEVEEIGEHLQTACDFRVYNXCKALIQKIAVSTQ
What is the function of this protein?
Implicated in endonuclease cleavage of capped RNA primers.  Displays an elongation factor activity in viral RNA synthesis.  Dispensable for viral transcription, but not replication (By similarity).
What are the official names of this protein?
Polymerase acidic protein, PA, Protein 2, P2, RNA-directed RNA polymerase subunit P2.
Protein: EFTS_KOCRD
Sequence: MANYTAADIKALRERTGAGMLDVKKALDEADGDAQKAQEIIRVKGLKGVTKREGRSTAEGIVLARTENNVGYMVEVNSETDFVAKSAPFVEFGNKVLDAAVAADAADLDALLAAEVDGKPISELVTETGALLGEKVVVRRVARVAGDHVAVYLHKTSKDLPAQVGVLLAVSGADAETAAHDVAVHIAAMSPAFLSEEDVPAETVENEKRVAEETARNEGKPEKIIPNIVQGRLKGYYKDVVLVDQDFAKDSKKSVGQVLSEAGATATAFARFRVGA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEDD1_ARATH
Sequence: MMSNLVEPSWRLLAASGGDTVKLFDVSADSGDPCVLSYTPSPGCAVNSVKWNHTNLVVASTGEDKKISLWRKNGQSLGTVPVTGKDGGDSAEECLSAISFSKKGSRYICSGGTGQIVKIWDLQRKLCIKKLKGHTSTITGVMYNCKDEHLASVSVGGDLIVHNLASGARATELKDPNGQVLRLLDYSRSSRHLLVTAGDDGTVHLWDTTGRSPKMSWLKQHSAPTAGVCFSPSNEKIIASVGMDKKLYTYDSGSRRSSSCIAYEAPFSSLAFGDNGYILVAGTSNGRVVFYDIRGKPQPVTVLHAFSNSEDVTSLSWQTSKPVIVNEKNYTSEMALLGSTVEDSVVIPDPLPSTTPSASQSAMAPGSRGVSASTVNASSVEQTPNRNHLWPSGPLGRLHALRANDSYNDDMGVFSPIIDVSSVEKWADSEGYNNKDHLVVDNKPSSLLFPSSSKGYSFGDNGSKEHPIFDWKPSSTSKQDDPRAAFSSFGSITPTASSKSEDSALTPPEAWGGDKFSEKFNQLANEKFSDKFSHLHAPSRLAVSSTGASTSGSMFSSSRDFPLSHGQTNFANASLEFPRIRDFSSTFETSSTQTDNNLPSSPLFTKGITAPGNIDSLRLSPNFTRRFSTYAERISTTSSFSDGASLSLGGSPKIKKTGSETREEVLNHLLARPETVVATEAGAMPLMNQGGLKQSQTDQQQVMGSSNFTLQLFQRTLEGTLDSFQNSIHDDVRNLHIEILRQFHMHEMEMSKVLSSILENQAEQMKELKLLRKENQELRQRL
What is the function of this protein?
Regulates microtubules organization in a centrosome-independent manner.  Required for the spindle to be positioned correctly and for the function of gamma-tubulin in organizing phragmoplast microtubules (PubMed:19383896).  Component of active gamma-tubulin ring complexes (gamma-TuRCs) associated with cortical microtubules in interphase cells (PubMed:25438942).  Mediates gamma-TuRC recruitment to the nucleation sites and is important for determining the ratio of branched to parallel nucleation (PubMed:25438942).  May mediate the localization of GCP2 and GCP3 to the nuclear envelope (PubMed:19383896).
What are the official names of this protein?
Protein NEDD1, Neural precursor cell expressed developmentally down-regulated protein 1 homolog, Protein GCP-WD.
What are the subcellular locations of this protein?
Nucleus envelope. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasm, cytoskeleton, microtubule organizing center. Note=First detected in prophase on the nuclear envelope, where it appeared to cap the future spindle poles. Later detected along kinetochore microtubules (MTs) of the metaphase spindle, with more prominent signals toward the poles. In anaphase, detected with the shortening kinetochore fibers. In the developing phragmoplast, localized mainly toward the minus end of MTs.
Protein: YQE2_SCHPO
Sequence: MPTILVINPNSSTFITTSMEEKLVPLVPSDVKLRFLTCPQPGAAVIDSITEATLTAALVFQALTPSVLDGVDAIAVACYSPTPLVDMIRESFALPCMGIVQASVLSALSVGQRIGILTSTYRSECLLYELLDSFGVSRTRVAAIASTGRTVLQLSQMPSQERETLLVQKAQELANTKGADVICLGGAALAAIRDQIQVAVGPNIPIIDGVHAAVELLAGLARQNLHTSKFGIYTYP
What are the official names of this protein?
Uncharacterized protein C576.02.
What is the protein family that this protein belongs to?
Belongs to the HyuE racemase family.
Protein: HIS6_CAUSK
Sequence: MLKTRIIPCLDVKDGRVVKGVNFVALRDAGDPVEQARAYDAAGADELMFLDITASSDNRGLLLDVISRTAEVCFMPVSVGGGVRQVSDMRRLLLAGADKVSVNTAAVENPDLVAAGADAFGAQCVVVAIDAKARGDGSGWNVWTYGGRKDTGIDVVDWAAKVVERGAGEILLTSMDRDGAKIGYDIPLLKAVTGAVTVPVIASGGAGTTDHLVEAARDGHAAAVLAASIFHFGEISIGQAKRAMADAGIPVRLDTLKGAA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_ECO8A
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEUR3_HUMAN
Sequence: MEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRRGLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSGRNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYTYYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVLYCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSSKDAPTIQQSSPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRPWILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGRNPSQFKSN
What is the function of this protein?
Exo-alpha-sialidase that catalyzes the hydrolytic cleavage of the terminal sialic acid (N-acetylneuraminic acid, Neu5Ac) of a glycan moiety in the catabolism of glycolipids, glycoproteins and oligosacharides.  Displays high catalytic efficiency for gangliosides including alpha-(2->3)-sialylated GD1a and GM3 and alpha-(2->8)-sialylated GD3 (PubMed:11298736, PubMed:15847605, PubMed:10861246, PubMed:20511247, PubMed:28646141, PubMed:10405317, PubMed:12011038).  Plays a role in the regulation of transmembrane signaling through the modulation of ganglioside content of the lipid bilayer and by direct interaction with signaling receptors, such as EGFR (PubMed:17334392, PubMed:25922362).  Desialylates EGFR and activates downstream signaling in proliferating cells (PubMed:25922362).  Contributes to clathrin-mediated endocytosis by regulating sorting of endocytosed receptors to early and recycling endosomes (PubMed:26251452).
What are the official names of this protein?
Sialidase-3, Ganglioside sialidasedis, Membrane sialidase, N-acetyl-alpha-neuraminidase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
Protein: RPOA_LEPBA
Sequence: MSPKNLLKGFKRPKKIEFTTDVNTPNYGKFVAEPFERGIGTTIGNSLRRTLMSSIEGAAISAIRIEGVSHEFSYIEGVAEDVTRIILNLKQVRIKYEPEDKEASKVIHLELKGAGYFRAADLAVDSSIEIMNPDLHIATLNEDANLIMDLEIQRGRGYVPAEDKKKDIEVLGTIPIDSIFSPIQKVLFEVSETRVAQRSDYEKLTMEVWTDGSVSPEDAVAQAAKILKDHLTVFINFEEEIEEEEEELDEADEKLKAALSKHVEELELSVRSTNVLRSLEIDFIGELVKRSEDEMTKSKHFSEQSLLELKAKLSSMGLSFGMRDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: Y236_HELMI
Sequence: MDQEQENIIVLTDEDGNELEFEELDRVEVDGKEYAILLPLDDEEDEAIILRVEYEENGEEVFSHIEDDEEWEKVADFWQELSEEDGEEE
What are the official names of this protein?
UPF0473 protein Helmi_02360.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: RL7_SALNS
Sequence: MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKSLEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ACPS_RICRS
Sequence: MLIGVGTDIVQISRIEKILHLYPELFAKKILTSKELKQFALLGKINHAAFLAKRFAAKEAVSKAFGVGIGQGINFKDITILNNDLGKPIVEVSSNYTNKLSPFNIHLSLADDYPVCVAFAVIESSYNVIRG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.