PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_CHLCH
Sequence: MGKIIGIDLGTTNSCVAVMQGSQPTVIENSEGNRTTPSVVGFTKTGDRLVGQAAKRQAITNPKNTIFSIKRFMGRRFDEVGEEKKMAPYELINDSGEARVKINDKVYSPQEISAMVLQKMKQTAEDFLGEKVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKKNASEKVAVFDLGGGTFDISILELGEGVFEVKSTDGDTHLGGDDFDQKIIDYIAEEFKKQEGIDLRKDAITLQRLKEAAEKAKIELSSRSDTEINLPFITATQEGPKHLVINLTRAKFEAISADLFNKVLDPCRRAVKNAKIEMREIDEVVLVGGSTRIPKIQALVKEFFGKEPNKSVNPDEVVAIGAAIQGGVLKGDVTDVLLLDVTPLSLGIETLGGVMTKLIEANTTIPTKKQEVFSTASDNQTSVEVHVLQGERPMAADNKTLGRFHLGDIPPAPRGIPQVEVIFDIDANGILHVSAKDKATGKEQSIRIEASSKLSDAEINKMKDDAKQHADEDKKRKEEIDIKNSADALIFSTEKQLTELGEKIPTDKKSALEGSLDKLRDAYKNGTTESIKSAMDDLNSQWNSIASDLYQSGAGAAQAQPEAPQNSGSSQSSGGDGAVNAEYEVINDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SYL_LEPBA
Sequence: MNYPFQDIEQKWQKYWDHHQTFRTNTHSSKPKYYCLDMFPYPSGAGLHVGHPEGYTATDIISRLKRMEGYEVLHPMGWDAFGLPAERYAMTTGIHPRTTTKNNIDTFRRQIKSLGLSYDWEREISTTHPDYYRWTQWIFLQIYNSYFDRKQNKAVPITTLIQTLEREGSLFFEGVELPKGIQFTASEWKSKSRKEKEDILSHFRLVYEANIPVNWCEALGTVLANEEVEEWTSKGYSVERKPMRQYMMRITAYAERLLNDLSLCEWPPSTLEMQRNWIGKSEGLELSFHVPSLNKDITVYTTRPDTIFGATYLVLAPEHALVAELTTPEQTEAVGQYQKDCSLKSDLERTELNKDKTGVFTGAYAQLPTDPSVKVPIYISDYVLISYGTGAIMAVPAHDQRDYDFAVKFNLPIKQVIDGKMETNLAFDSKDSVCINSSSAEVQLDGKSYKDAFQTMVVWAEKKGIGRKKIQFKLRDWLFARQRYWGEPIPLVHFEDGSPKALSDSELPLVLPDLEEFKPSGTGESPLALAKDWLVYKDPETGEIGKRETNTMPQWAGSCYYYLRYIDPRNNDKLIDPELEKMWMPVEVYVGGAEHAVLHLLYSRFWHKILFDLGHVSTPEPFKKLVHQGLILGEDKGKMSKSRGNVVNPDDVVSEFGADTLRLFEMFMGPFEMSKPWSKNGVDGVFRFLNRVWRLFHSGENESFFVEDIEPNEAEQKTLHRTIKKVKDDIDSFSFNTAVSQMMIFINEFTSNPRKPKQVLEPFVLALSPFAPHLAEELWAKLGHTDSLAYHPYPKWDEKYLIDANITIVVQVNGKMRGEFLAPREIEEKEALSLAKEVEKAKPFWVGKEIKKEIYVKGKLVNIVVAG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_SHIBS
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVSMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UB2G2_HUMAN
Sequence: MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKIAKQIVQKSLGL
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:20061386).  In vitro catalyzes 'Lys-48'-linked polyubiquitination (PubMed:20061386).  Involved in endoplasmic reticulum-associated degradation (ERAD) (PubMed:22607976).  Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation (PubMed:23223569).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 G2, E2 ubiquitin-conjugating enzyme G2, Ubiquitin carrier protein G2, Ubiquitin-protein ligase G2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Lipid droplet.
Protein: RUSD4_DANRE
Sequence: MRHAREVTFARLMRTFAAVSDTQTVASKHKTAPKAADIANRLRKEKEKEKDDKNEVPVSPLQSRVNELKQFSQQLQSVHPSVFAKALYRSSLYEDQNIIAINKPYDVPLHNINGIRNSIAECLPLLAKITDNMRPGSQLHLCHKLEKETTGVLILAKTEEAAEHVQTLIQSHKVEMKYLAITVGVPVPSEGVIDIPVIERAVVGPQPHFKMALSPLFKVNEDGDGVTRVRAHRQAHAAVTRYQVLDNTSGCSLVELQPLTGVKNQLRVHMALALTCPILGDHKYSHWSKLAPQKLPEGTLRRLGLVQSKTRYLPLHLHSRRIVLPGFKGHRDITVSCPLPKYFINALKRLEIPLPAKE
What is the function of this protein?
Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates.  Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA).  This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome.  Acts on position 39 in mitochondrial tRNA(Phe).  Also catalyzes pseudouridylation of mRNAs in nucleus: acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions.  Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing.
What are the official names of this protein?
Pseudouridylate synthase RPUSD4, mitochondrial, RNA pseudouridylate synthase domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Mainly localizes to mitochondrion. Localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly. Also found in nucleus and cytoplasm.
Protein: CDC6M_HALMA
Sequence: MPNNESTQTTVDEILNVDEDNDEDESNIFEKPWLLEIDNVPDANRIVGRDDHITFLAKNLRKMRTNSVPDNVLEWGETGTGKTLVARHVCERLEAATEGTDSPIVTAYINPDPISTYTSTFRKIAEQVNAKAENPLEVPYQGLSAEHYRDQKLWPVVQREFSGGLVVIIDEIDKHGEVNEVLYTLSRTQSKDDVDFPVITIGISNDIEFKGEIESRVQSTLQPEHRTFTPYEEDQLIAILENRRDAFYDGVLDDEVIPTTAELAAEEHGDARRAVRLFRNAGEIADEEGDDIVTAEHVHEADELVEVELFMEMVKGTPLSGKLLLFALTRLDRNNPEKEWFRTSEIHEVYQTVARDVKVEPKGYNRALELLNKHVTTGVLESKKKEGGDQGKFRSYSLQGDVESTRTGLINSTPELQTLMGW
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 13.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: Y2160_LISIN
Sequence: MENDRQAIVVWMNHLKQVRSLKRFGNVHYVSRKLKYAVLYCDMAEVEDISNKVSRFHYVKRVEMSFRPFLKTEYESKKEMMYEHKNEDVQISI
What are the official names of this protein?
UPF0298 protein lin2160.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBP4_DANRE
Sequence: MDKPVCLIDTGSDGKLCVQQAALQVLQQIQQPVVVVAVVGLYRTGKSFLMNRLAGKRTGFALSSNIKPKTEGIWMWCMPHPTKAGTTLVLLDTEGLEDVEKGDSKRDTYIFSLAVLLSSTLVYNSRGVIDNKAMEELQYVTELIEHIKVTPDEDADDCTAFAKFFPHFIWCLRDFTLELKLDGKDLTEDEYLEFALKLRPGTSKKVMMYNLPRECIRKFFPCRTCFTFPSPTTPEKRSILESLSPAELDPEFLEVTKRFCKFVFDRSEVKQLKGGHTVTGRVLGNLTKMYVDTISSGAVFCLENAVIAMAQIENEAATQEGLEVYQRGMEKLKSSFPLELEQVSSEHQRLSSMATQAFMARSFKDTDGKHLKALEGEMGKLFDAYRSQNKQVGLETHCDLLLYMRCKDPLILHVYFFPVNDARSKEKVEQNERSSLPISHPRPDRPFQVKTPHVLEVPGASVYPEEGISFRTDVEPNFFKVRKLQVDDVQMNLVRQKDKMSVWTTTIWKEEFVHLQQVRDERKLNSEIEKNDFFNAHRVAFIERVTNVKSIADKLHGQRIIHKELYSEITQTNVTRQQIMRKICDSVDSSGRIAKCKFIDILQEEERCLLEDLKQSES
What is the function of this protein?
GTPase that plays important roles in innate immunity against S. typhimurium pathogens by mediating formation of an inflammasome in neutrophils (PubMed:27363812).  Neutrophils are recruited to the infection site, and then mediate bacterial clearance through the Gbp4 inflammasome-dependent biosynthesis of prostaglandin D2 (PubMed:27363812).
What are the official names of this protein?
Guanylate-binding protein 4, GTP-binding protein 4, GBP-4, Guanine nucleotide-binding protein 4.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
Protein: YBIX_ECOLU
Sequence: MMYHIPGVLSPKDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSALYAALQNEVLNAVNQHALFFAAALPHTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFDLDNNIQSLKSRYGESEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.
Protein: DMS1A_WHEAT
Sequence: MGAGDKTAAGMPRIGMGTAVQGPKPDPIRRAVLRAIEVGYRHFDTAAHYETEAPIGEAAAEAVRSGAVASRDDLFITSKLWCSDAHRDRVVPALRQTLRNLQMEYVDLYLVHWPVSMKPGRFKAPFTAEDFVPFDMRAVWEAMEECHRLGLAKAIGVANFSCKKLETLLSFATIPPTVNQVEVNPVWQQRKLREFCRGKGIQLCAYSPLGAKGTHWGSDAVMDAGVLQEIAASRGKSVAQVCLRWVYEQGDCLIVKSFDEARMRENLDVDGWELTEEEHRRIAEIPQRKINLGKRYVSEHGPYKSLEELWDGEI
What is the function of this protein?
Catalyzes the reduction of a 3''-keto intermediate during the biosynthesis of 2'-deoxymugineic acid (DMA) from L-Met.  Involved in the formation of phytosiderophores (MAs) belonging to the mugineic acid family and required to acquire iron.
What are the official names of this protein?
Deoxymugineic acid synthase 1-A, TaDMAS1.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: Y709_METJA
Sequence: MKNVEILLDDPKKAVIEVSKPIIVATFIESIYSLVDSIWVSGLGADALAAVGASFPILISIYAVSWGLSIGISSGIARRVGAKNKEEADKVANHAIILALIAGILYIIAVYPNLDTLFSLMGTYGDCKSLAIKYSSILVLGTVIFTICDALYGIFRGEGNTKIVMIASVIGTLTNIILDPIFIYMLNLGISGASYATLIAIIISLLILAYELFIKKSCYVTVKLSKFKPDLKIIADLIRVGIPSALIEITVAVSFFIMTSIIMMVGDSRGLAVYTGALRITEFGFIPMLGLASGATSVIGATYGARSFEKLKTAYFYTIKIGVLMEIIIVALIMLLSPILAYLFTYTKTSMGIHEELVKALRIVPLYLLFTPFILTTSAMFQGIGKGEKSLIISIFRSLICHISYAYLFAVILGLGMFGIYSGLVVGEFTAGIFAFLFGVLAIKALIKSK
What are the official names of this protein?
Uncharacterized transporter MJ0709.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLYA_BRUC2
Sequence: MSQANAATKASSDVFFNASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRYYGGCQYVDVVEELAIERAKKLFSAEFANVQPNSGSQMNQAVFLALLQPGDTFMGLDLNSGGHLTHGSPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAGGTAYSRIWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRGPRGGMILTNDADIAKKINSAVFPGLQGGPLMHVIAGKAVAFAEALKLEFKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAALGRANITCNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGVAEFKEIGSLIAEVLDGLKVANSDEGNAAVEQAVKEKVIALTGRFPMYGYQG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRFD_DICDI
Sequence: MGRKKIKIQRIPDERNRQVTFNKRKNGLIKKAMELALLCDSTVSLVIVNNSPNAKEKYFQYISSGLPSPMESIPDLGPEISQKFTDHDYDKIFNKKEKGDFNDDYIGGDTASHSEEEDHKSPSSTPELLGYNHHNHHHHHHQYNNNSNNNNNNHNNNHNNYNNSNNINGHNNHYNHNNLKLNSNNNNNNSQFNSSQHINKPILSIKPSQTQENHNHYNNYSSHLSNNNNNNNSSNNNNNSNNNNNNNNNNNTNNNNTNNNNNNNNNNNNNNNNNNNNNNNNNMSPIGSPPSKCQQVPAFDSTQATQALLSLHNASKLFCSSPEDTSPMTSPRTPPFSSTNTNTLQTSPNSQQKSKSLPPLIFNENNNQNNNNQNNNQNNNNNNSNNTNTNNNNQNNSSRSILLPPISLYNSNSNSNSSSTLTSPTSSSSNLNDDLFLKKRKLELIH
What are the official names of this protein?
Serum factor response D.
What are the subcellular locations of this protein?
Nucleus.
Protein: FES1_YEAST
Sequence: MEKLLQWSIANSQGDKEAMARAGQPDPKLLQQLFGGGGPDDPTLMKESMAVIMNPEVDLETKLVAFDNFEMLIENLDNANNIENLKLWEPLLDVLVQTKDEELRAAALSIIGTAVQNNLDSQNNFMKYDNGLRSLIEIASDKTKPLDVRTKAFYALSNLIRNHKDISEKFFKLNGLDCIAPVLSDNTAKPKLKMRAIALLTAYLSSVKIDENIISVLRKDGVIESTIECLSDESNLNIIDRVLSFLSHLISSGIKFNEQELHKLNEGYKHIEPLKDRLNEDDYLAVKYVL
What is the function of this protein?
Involved in protein translation, propagation of [PSI+] prions, and polyamine tolerance.  Functions as a nucleotide exchange factor (NEF), which accelerates the release of ADP, for the cytosolic Hsp70 chaperone SSA1 and the ribosome-associated Hsp70 chaperone SSB1.  Required for fully efficient Hsp70-mediated folding of proteins.
What are the official names of this protein?
Hsp70 nucleotide exchange factor FES1, Factor exchange for SSA1 protein 1.
What is the protein family that this protein belongs to?
Belongs to the FES1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_BACC2
Sequence: MGIKKYNPTTNGRRNMTTNDFAEITTDRPEKSLLAPLSKKAGRNNQGKITVRHQGGGHKRQYRIIDFKRNKDGIPGRVATIEYDPNRSANIALINYVDGEKRYILAPKSLEVGMEVMSGPEADIKIGNALPLINIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGKEGKYVLVRLTSGEVRLVLSACRASIGQVGNEQHELIKIGKAGRSRWLGKRPTVRGSVMNPVDHPHGGGEGRSPIGRKSPMSPWGKPTLGFKTRKKNKASDKFIVRRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: EXGD_ASPFC
Sequence: MPTHSRSRDRYGGRDSDREARYDYDYARRRYATDDDDDYDDDELEHDLTERRYRRDGYRPPRESRARGYYERDAEGAADEELLGNERDPGPRASRSYGDDYDARRREHSRAREAPRRSERHRDRDREGRSRRRAYEDDGRHRTRDGRRDRGRESDGEARRSRRREAGRETAARKHRSSDSTNSASHLLSADALAKLGAQYEKEERRKREIAKDAAKAERKRQKKLAVVGEETRALRDPPGESHRDRTKARVASGAYLEEGRSPEMRVRHRGGGGPAMEARWRKEGSWGGTMDDSGGGRPFWKRKRWIGLGALIIILVIVIPVAVVVSKKHDNKSDPADSQGTSPGKSNLDGLSHDSIPAYAQGTYLDPWTWYDTTDFNVTFTNETVGGLSIMGLNSTWDDSARPNDNVPPLNEPFPYGSQPIRGVNLGGWLSIEPFIVPSLFDSYSSVSGIIDEWTLSKRLGSSAASTLEKHYATFITEQDFADIRDAGLDHVRIQYSYWAVATYDDDPYVAKISWRYLLRAIEYCRKYGLRVNLDPHGIPGSQNGWNHSGREGVIGWLNGTDGELNRNRSLAVHDSVSKFFAQDRYKNIVTIYGLVNEPLMLSLSIEDVLDWTTEATKLVQKNGITAYVALHDGFLNLSKWKSMLKNRPDKMLLDTHQYTIFNTGQIGLNHTAKVNLICNDWYNMIKEINSTSTGWGPTICGEWSQADTDCAKYLNNVGRGTRWEGTFSLTDSTQYCPTADTGPPCSCANANADVSKYSADYKKFLQTYAEAQMSAFETGQGWFYWTWRTESAAQWSYRTAWKNGFMPAKAYAPSFRCGDAVPDFGDLPEYY
What is the function of this protein?
Glucosidase involved in the degradation of cellulosic biomass.  Active on lichenan (By similarity).
What are the official names of this protein?
Probable glucan 1,3-beta-glucosidase D, Exo-1,3-beta-glucanase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: X_HBVOR
Sequence: MAARLCCQLDTARDVLCLRPVGAESRGRPFSGSVGALPPSSPPAVPADHGAHLSLRGLPVCAFSSAGPCALRFTSARCMETTVNAPRNLPKVLHKRTLGLSTMSTTGIETYFKDCVFKDWEELGEEIRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: NUOB_NITWN
Sequence: MEERRSRMGLNSPTSKVAYAGGTVTGAAGTSILDPATGRPVGASDPYFLEVNHELSDKGFFVAAADDLITWARTGSLMWMTFGLACCAVEMMQVSMPRYDVERFGFAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILLLQKKIRRVGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MODA_XANAC
Sequence: MRMIGFWQRALCVLMLTLPVLASAQTAPVTVFAAASLKESMDEAATAYEKATGTPVRVSYAASSALARQIEQGAPADVFFSADLEWMDYLQQHGLVLPAQRHNLLGNTLVLVAPASSKLRVDPRAPGAIAKALGENGRLAVGQTASVPAGKYAAAALRKLGQWDSVSNRLAESESVRAALMLVSRGEAPLGIVYGSDARADAKVRVVATFPDDSHDAIVYPVAALKNSNNPATAAFVSWLGSKPAKAIFARRGFSLKD
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in the transport of molybdenum into the cell (Probable).  Binds molybdate and tungstate with high affinity in vitro (PubMed:16879982).
What are the official names of this protein?
Molybdate-binding protein ModA, Molybdate/tungstate-binding protein ModA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein ModA family.
Protein: RS15_STRZJ
Sequence: MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIKQHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: G3PA_PEA
Sequence: MASATFSVAKPAIKANGKGFSEFSGLRNSSRHLPFSRKSSDDFHSLVTFQTNAVGSSGGHKKSLVVEAKQLKVAINGFGRIGRNFLRCWHGRKDSPLDVIAINDTGGVKQASHLLKYDSTLGIFDADVKPVGTDGISVDGKVIKVVSDRNPANLPWKELGIDLVIEGTGVFVDREGAGRHITAGAKKVLITAPGKGDIPTYVVGVNADAYTHADDIISNASCTTNCLAPFVKVLDQKFGIIKGTMTTTHSYTGDQRLLDASHRDLRRARAAALNIVPTSTGAAKAVALVLPTLKGKLNGIALRVPTPNVSVVDLVVQVSKKTFAEEVNEAFRESAAKELTGILSVCDEPLVSVDFRCTDVSSTVDSSLTMVMGDDLVKVIAWYDNEWGYSQRVVDLADIVANNWK
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic, NADP-dependent glyceraldehydephosphate dehydrogenase subunit A.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: O26E_CONVC
Sequence: MEKLTILLLVAAVLMSTQAMFQGGGEKRPKDKIKFLSKRKTNAESWWEGECLGWSNGCTQPSDCCSNNCKGRNCDIW
What is the function of this protein?
Inhibits voltage-gated ion channels.
What are the official names of this protein?
Conotoxin Vc6.14.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14_AKKM8
Sequence: MAKKSWIARDKKKAETVKRYAELRAQLKAEKDYIGLTMLPRNASPTRTVNRCLVSGRRRAFIRRFKLSRISFRELANAGMIPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: COMB_CLOBK
Sequence: MNIDIVISADHIDEKRLINKTVIIIDILRATSVITTAINNGCKKVIPVLTVEEAKDIAKNSKEDIILGGERNALKIDGFNFSNSPLEYTKNYVEGKTVVLSTTNGTRAINNSFNAKTILISALINSKATAKAIDKLNEDLIIINSGTNGQFSIDDFICSGYLIDCLYNIRKDLELSDIAKTAHYIYMNNKDIESFVKKATHYSRLKSLNLEKDLEYCFQKDIIDVVPQYKDGYIIKSNI
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: WDR6_PONAB
Sequence: MDALEDYVWPRATSELILLPVTGLECVGDRLLAGEGPDVLVYSLDFGGHLRMIKRVQNLLGHYLIHGFRIRPEPNGDLDLEAMVAVFGSKGLRVVKISWGQGHFRELWRSGLWNMSDWIWDARWLEGNIALALGHNSVVLYDPVVGCILQEVPCTDRCTLSSACLIGDAWKELTIVAGAVSNQLLVWYPATALADNKPVAPDRRISGHVGIIFSMSYLESKGLLATASEDRSVRIWKVGDLRVPGGRVQNIGHCFGHSARVWQVKLLENYLISAGEDCVCLVWSHEGEILQAFRGHQGRGIRAIAAHERQAWVITGGDDSGIRLWHLVGRGYRGLGVSALCFKSRSRPGTLKAVTLAGSWRLLAVTDTGALYLYDVEVKRWEQLLEDKHFQSYCLLEAAPGPEGFGLCAMANGEGRVKVVPINTPTAAVDRTLFPGKVHSLSWALRGYEELLLLASGPGGVVACLEISAAPSGKAIFVKERCRYLLPPSKQRWHTCSAFLPPGDFLVCSDRRGSVLLFPSRPGLLKDPGVGGKAGAGAGAPGVGSGSSGGGNAFTGLGPVSTLPSLHGKQGVTSVTCHGGYVYTTGRDGAYYQLFVRDSQLQPVLRQKSCRGMNWLAGLRIVPDGSMVILGFHANEFVVWNPRSHEKLHIVNCGGGHRSWAFSDTEAAMAFAYLKDGDVMLYRALGGCTRPHVILREGLHGREITCVKRVGTITLGPEYGVPSFMQPDDLEPGSEGPDLTDIVITCSEDTTVCVLALPTTTGSAHALTAVCNHISSVRAVAVWGIGTPGGPQDPQPGLSAHVVSAGGRAEMHCFSIMVTPDPSTPSRLACHVMHLSSHRLDEYWDRQHNRHRMVKVDPETRYMSLAVCELDQPSLGPLVAAACSDGAVRLFLLQDSGRILQLLAETFHHKRCVLKVHSFTHEVPNQRRRLLLCSAATDGSLAFWDLTTMLDHDSTVLEPPVDPGLPYRLGTPSLTLQAHSCGINSLHTLPTREGHHLVASGSEDGSLHVFVLAVEMLELEEAVGEAGLVPQLRVLEEYSVPCAHAAHVTGLKILSPSIMVSASIDQRLTFWRLGHGEPTFMNSTVFHVPDVADMDCWPVSPEFGHRCALGGQGLEVYNWYD
What is the function of this protein?
Enhances the STK11/LKB1-induced cell growth suppression activity.  Negative regulator of amino acid starvation-induced autophagy.
What are the official names of this protein?
WD repeat-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR6 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes in the cytoplasm with STK11/LKB1.
Protein: ELAV4_XENTR
Sequence: MEWNGLKMIISTMEPQVSNGPTSNTSNGPSSNSRNCPSPMQTGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGTQFEEHFKDLATGTKWKPLTEEGPIFGKGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGAAEPITVKFANNPSQKTSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKS
What is the function of this protein?
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs (By similarity).  Plays a role in the regulation of mRNA stability, alternative splicing and translation (By similarity).  Binds to AU-rich element (ARE) sequences in the 3' untranslated region (3'UTR) of target mRNAs (By similarity).  Mainly plays a role in neuron-specific RNA processing (By similarity).
What are the official names of this protein?
ELAV-like protein 4, Protein ElrD.
What is the protein family that this protein belongs to?
Belongs to the RRM elav family.
What are the subcellular locations of this protein?
Cytoplasm. Perikaryon. Cell projection, axon. Cell projection, dendrite. Cell projection, growth cone.