PharMolix/UniProtQA huggingface dataset:
Protein: PDRP1_LISW6
Sequence: MTQPAVYVVSDSTGETAELVTRAALSQFGQTPKFIHRFHHVDSSHMIEEIVDLVAVNNGIIVHTIVLESVREELNKTAQAFGVPIIDLFGPLLNQLEETYKIKPLSEPGRVRSMDEAYFNKVAAIEFAVENDDGRNPRGILQADYVLIGISRTSKTPLSQYLALKGLKIVNIPIVPEAQIPDELFEIDPQKIIGLKISKQKLTKIRQERLISIGLPGAGTYASNQRIDEELAIFDKLASKLNCFVLDVTNKAIEETANEILIHIGEIVDENLEL
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 1, PPDK regulatory protein 1.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RUVA_TREDE
Sequence: MFNSISGILSGKTTDSVYVENSGIEWEIFVSALALDALGTVGKEVKVYTWLYHREDQMRLFGFPNQAERSLFLDLTKVEGVGPRQALKIMSGLNSSSLEKALEEGDLDTLQKAPGVGKKTAQKMILALKGKLTNLNEVSSKGQASVSCEYEDIVTALTEMGFERKSVIVQVEKIAEEMKAAGSDPLKNEEELFRRSIVALS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TRHO_PROM9
Sequence: MKGKNYKIVSLYSFFPFQENLIIDLKSKLLEIGYENDLSGLLIFASEGINGTICAEKNVIDIVINLLNKYADNRNLNIKVNFSKKKVFKKLKIKIKKEIVTMGVPEINPSENNGTYIDSANWNKLIKNQNTIVIDTRNHYEVSVGTFQNSINPNTRNFSEFPKWVDDQLDTHLENKESTNIAMFCTGGIRCEKATSLLKKKGYKNIYHLQGGILQYLDDIPKEKNLFEGECYVFDKRVALDQELEKGSYSICHACGMPVSIQDQERKEYRKGIQCHFCIDQFSDDDRKRFEERQKQIDRLKVGNHKIFKD
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: EFTS_COREF
Sequence: MANYTAADVKKLRELTGSGMLDCKKALEESAGDFDKAVEILRIKGAKDVGKRAERNATEGLVAVSGNTMIEVNSETDFVAKNDEFKNFAAKIAEAAAAAKANSPEELAAVDVDGQSAQDALQEFSAKIGEKLELRRAVTLEGDNVAVYLHHRSADLPPSVGVLVAYTGEGEEAEAAARQAAMQIAALRASYLTREDVPAEVIEKERSIAEQITREEGKPEQAIPKIVEGRLNGFYKENVLLEQASVADSKKTVKALLDEAGATVTAFARFEVGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG3_CANGA
Sequence: MQTVRSEDNPPKKEEFKRPPIDLLQDLKDGINHVVYNPLGNKIVMPLMFLLESVLLKYVIAAIPYTEIDYKAYMEQVEMIYEEGNYNYLEITGGTGPLVYPAGHVLIFRVLNYFTEGMNHIEVGQKIFRYLYLITLLMQYTCYYQLRLPPWCVVLASLSKRLHSIYVLRLFNDCFTTFFMVLFVLLYTLRSNNSTKMSMVISTFGSLVYSMAISVKMNALLYLPGYLVSTYLINEGKLINCLISASVILFWQVIVSLRFLRSYPVEYLAGAFDFSRQFMFKWSVNWQFLDEDAFQDRVFHTTLLGSQFVAVVAMTLCLYPRLPLDAWKSLKAPFTQVVIADLRFIVPFLLMTSNFIGVLFSRSLHYQFLSWYHWTLPCLIYWSKLPMPLGFIWYICHEYCWNSYPPNEKASILLFTLNASLLCLLAINCMRPVIVNIKRKQQ
What is the function of this protein?
Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, Asparagine-linked glycosylation protein 6, Dol-P-Man-dependent alpha(1-3)-mannosyltransferase, Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS9_AFIC5
Sequence: MSDTMQSLDQLSALKTAAPDAPKREKKVDKQGRAYATGKRKDAVARVWIKPGSGKIVVNTRDVEVYFARPVLRMLIQQPIVAAARQGQYDVVATVAGGGLSGQAGAVRHGISKALTHFEPDLRGVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: G6PI_HALH5
Sequence: MSGKVCFDYSKALDFIQEHELDNLQDQVHAAHRALHDGTGAGNDFLGWIDLPVNYDREEFSRIQKAAEKIRNDSDVLLVIGIGGSYLGAKATLEALNHSFYNIVDKSERKGPQIFFVGHHISSTYVQELFDVLEGKDVSINVISKSGTTTEPAIAFRIFRDYLEKKYGKEESRKRIYATTDRERGALKTLANEEGYESFIIPDDVGGRFSVLTAVGLLPIAASGLDIEAMMKGAADARDAFRNSDLKENPAYQYAVVRNALYNKGKTIELMVNYEPALQYFSEWWKQLYGESEGKDGKGIFPASVNFSTDLHSMGQYVQDGRRDLFETIIQVEKPKKNMTIEKADQDLDGLNYLAGETMDFVNKKAFEGTLLAHVDGGVPNLVVSVPELDEYYMGYLMYFFEKACGLSGYLLGVNPFDQPGVEAYKKNMFALLGKPGFEEQKAALEKRLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
Protein: EFTS_METEP
Sequence: MANITAALVKELREKTGAGMMDCKGALNETNGDLEAAVDWLRKKGLAKAAKKAGRVAAEGLVAVESAGRHAAVVEVNSETDFVARNDGFQAFAREAAKLALNTDGTLEGLQAATFPGSSETVQEKLSNLIATIGENMTLRRVAKLEVSKGVIASYVHGQINEGLGKIGVLVALESEGDVEFLSTLGRQIAMHVAATNPTALDASGVDQAVVERESNILREKNAGKPDHVMAKIVESGLKSYYKEVTLLEQPFVHDGSKTVSQILKEAAGKAGGEVAIKGFVRYALGEGIEKEEGPDFAAEVASMSR
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPF_CLAM3
Sequence: MANPLRKTMVYLGLADEELDYQQGQQPAQQQQSPVQAVPTPAPAPQQQAKRAPVTPLHKPSTTTRNAAPAEMNEILTVHPKAYKDAQVIAENFREGVPVIINLSQMTDDDARRLIDFASGLSIGLYGKIERVTAKVFLLSPSHVAVSGEQSATEAEVEASFFGR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: PRGR_CHICK
Sequence: MTEVKSKETRAPSSARDGAVLLQAPPSRGEAEGIDVALDGLLYPRSSDEEEEEEENEEEEEEEEPQQREEEEEEEEEDRDCPSYRPGGGSLSKDCLDSVLDTFLAPAAHAAPWSLFGPEVPEVPVAPMSRGPEQKAVDAGPGAPGPSQPRPGAPLWPGADSLNVAVKARPGPEDASENRAPGLPGAEERGFPERDAGPGEGGLAPAAAASPAAVEPGAGQDYLHVPILPLNSAFLASRTRQLLDVEAAYDGSAFGPRSSPSVPAADLAEYGYPPPDGKEGPFAYGEFQSALKIKEEGVGLPAAPPPFLGAKAAPADFAQPPRAGQEPSLECVLYKAEPPLLPGAYGPPAAPDSLPSTSAAPPGLYSPLGLNGHHQALGFPAAVLKEGLPQLCPPYLGYVRPDTETSQSSQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKLNKMKVVRTLDVALQQPAVLQDETQSLTQRLSFSPNQEIPFVPPMISVLRGIEPEVVYAGYDNTKPETPSSLLTSLNHLCERQLLCVVKWSKLLPGFRNLHIDDQITLIQYSWMSLMVFAMGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLSMWQLPQEFVRLQVSQEEFLCMKALLLLNTIPLEGLRSQSQFDEMRTSYIRELVKAIGLRQKGVVANSQRFYQLTKLMDSMHDLVKQLHLFCLNTFLQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity). SUBCELLULAR LOCATION: [Isoform A]: Nucleus. Cytoplasm. Note=Mainly nuclear.
Protein: RLME_BURPS
Sequence: MAKNRFNQSWLHDHINDPYVKMAQREGYRARAAYKLKEIDEQDKLIRPGQVIVDLGAAPGSWSQYARNKLAQGKRRDAVREGGIDGTIIALDMLPMEPVADVHFIQGDFREESVLHQLEEVLAGRAVDLVISDMAPNLSGVAVADAARIEHVCDLALEFAQNHLKPDGALLVKCFHGSGYSQIVEKFKHQFKTVAPRKPKASRDKSSETFILGRHLKQPR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERC6L_MOUSE
Sequence: MEASQGLAEVETLSPQLAESYLRYVQEAKEAAKNGDLEESLKLFNLAKDIFPTKKVMSRIQKLQEALEQLAEEEDDDEFIDVCSSGLLLYRELYEKLFEHQKEGIAFLYSLYKDGRKGGILADDMGLGKTVQIIAFLSGMFDASLVNHVLLIMPTNLINTWVNEFAKWTPGMRVKTFHGSSKSERTRSLTRIQQRNGVVITTYQMLLNNWQQLASFNGQAFVWDYVILDEAHKIKSASTKSAVCARAIPASNRLLLTGTPVQNNLQELWSLFDFACQGSLLGTLKTFKMEYEHPIIRAREKDATPGEKALGLKISENLMEIIKPYFLRRTKEEVQTKKADNPEARLGEKNPAGEAICDMFSLARKNDLIVWIRLLPLQEEIYRKFVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACRLLNLGTATFSAQDENEQEDVSNMNSIDHLPDKTLIQESGKMIFLMSLLERLQDEGHQTLVFSQSIKILNIIERLLKNKHFKTLRIDGTVTHLWEREKRIQLFQQNKEYSVFLLTTQVGGVGLTLTAATRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYFTKQELKELFTVGDLQKSATQMQLQCLHAAQRRSDEKLDEHIAYLHLLGIAGISDHDLMFTRDLSVKEELDMLEDSQYIHQRVQKAQFLVESESQNTVQRQTTGIEETWLKAQEFPSQQKKKGTEFNKPQPQPSRLLTKPTQVEAISSQMASITICDQSAESEPQEHSEVHDVTSLQGSHHFNSTSDAGTIASLPQGAESIGEVSTDSLLSPAKGFAAENDAMQKKGLQASPGQEAPSENLGSFHYLPRESSKASLGPNLDLQDSVVLYHRSPTANENQNLESDVPMIEISDDLSEPPSALQGAQAIEAQLELKEDDPLKSPPQYACDFNLFLEDSADTRQNLSSKFLEHVEKEKSLQSPAANSRAKSALTLSLDSSPKSDEESEVISVKTKSKTRRILSDDEDEDEEDAFKGSHTNSINISPFPFSSVKQFDASTPQSGSNPSRRFFSPKTPGEVNTSLHSRRSLASRRSLINVVLDDVEDMEERLDNSSEEESEPGLSEENNEEEALACTEEQPSGATLASGNKSSNLTMSEPTSPAPQSSPCAPEPSSSDPMPDPPQDLAVEAGNDYESLVARGKELKECGKIQEALNCLVKALDIKSADPEVMLMTLSLYKQLNI
What is the function of this protein?
DNA helicase that acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.  Functions as ATP-dependent DNA translocase.  Can promote Holliday junction branch migration (in vitro).
What are the official names of this protein?
DNA excision repair protein ERCC-6-like, ATP-dependent helicase ERCC6-like.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Chromosome, centromere. Chromosome, centromere, kinetochore. Chromosome. Note=Localizes to kinetochores, inner centromeres and thin threads connecting separating chromosomes even during anaphase. In prometaphase cells, it mostly concentrates in between kinetochores. In metaphase, it localizes to numerous thin threads that stretch between sister kinetochores of the aligned chromosomes and are composed of catenated centromeric DNA. Evolution from inner centromeres to thin threads takes place in response to tension. Resolution of thin threads requires topoisomerase 2-alpha (TOP2A) after anaphase onset.
Protein: RS15_STAEQ
Sequence: MAISQQRKDELIKEYRVHETDTGSPEVQIAVLTAEITALNEHLREHKKDHHSRRGLLKMVGRRRHLLNYLRSKDIQRYRELIKSLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HGD_BURCH
Sequence: MTLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFEPYAGAQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFVDGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGELLIVPQQGRLFIATEFGRLDVEPFEIAVIPRGVRFAVALPDGNARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQAAYEDREGAFELIAKLNGRLWRADIGHSPLDVVAWHGNYAPYKYDLRLFNTIGSISFDHPDPSIFLVLQAQSDTPGVDTIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDATMAFMFETRTLIRPTRYALDTAQLQADYFECWQGIKKHFNPEQR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: RMLC_NEIGO
Sequence: MDIIDTALPDVKLLKPQVFTDGRGFFMETFRDGWFKENIADRTFVQENHSNSSKGVLRGLHYQTENTQGKLVRVVVGEVFDVAVDMREGSPTFGKWAGATLSAQNRYQLWIPEGFAHGFCVLGDAAEVVYKCTDYYNPETEQVLIWNDPAIGIGWPLQTAPLLSPKDLAGKTWAQAEKSALRFPDKKCRPNVSDGIFSDRLPTRLQYALCKEKHPGNEERQAQPRSGGIPVLQIQRERRIRAAVGHREGNNKRHNYTNQAFTDNQACREKRTDTVGVFQTAFAVFRLLANDVFQHRRQHRACHDGHIDGRRQINAHTDRKDGQGKFTA
What is the function of this protein?
Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
What are the official names of this protein?
dTDP-4-dehydrorhamnose 3,5-epimerase, Thymidine diphospho-4-keto-rhamnose 3,5-epimerase, dTDP-4-keto-6-deoxyglucose 3,5-epimerase, dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase, dTDP-L-rhamnose synthase.
What is the protein family that this protein belongs to?
Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
Protein: RS3_STRR6
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQKELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINIIEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GDF11_RAT
Sequence: MVLAAPLLLGFLLLALELRPRGEAAEGPAAAAAAAAAAAGVGGERSSRPAPSAAPEPDGCPVCVWRQHSRELRLESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETVISMAQETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQLWVYLRPVPRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSLKIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPFMELRVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
What is the function of this protein?
Secreted signal that acts globally to regulate anterior/posterior axial patterning during development.  May play critical roles in patterning both mesodermal and neural tissues.  It is required for proper vertebral patterning and orofacial development.  Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.
What are the official names of this protein?
Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: BOP1_DROPS
Sequence: MTKKLTIKRKVKEPEPQNEAPDSHESSDNEEEEEEDLLQAVKDPGEDSTDDEGIDQEYQTDSSEDLEFESDEEGNYLGRKGAEGSSGDDDEESAEDEEEEDDADAKKSSKNNDEEAATTSKSIKKSQEKPTSSNKVVPVVPARDPSKVEYADSDTSDEEDIRNTVGNIPMHWYDEYKHIGYDWDAKKIVKPPKGDQIDDFLRKIEDPNFWRTVKDPLTGQEVLLTDADIALIKRINSGRIPNEEHDEYAPWIEWFTSEVEKMPIKNVPDHKRSFLPSGSEKKTVSRMVHALKMGWMKTTEEVQREKQEKRGPKFYMLWETDTSREQMRRIHDPVSAPKRDLPGHAESYNPPPEYLFDEKEAKEWHKLKDEPHRRKLHFMPQKFKSLREVPAYSRYLRERFLRCLDLYLCPRAKRVKLNIDAEYLIPKLPSPRDLQPFPTVESLVYRGHTDLVRSVSVEPKGEYLVSGSDDKTVKIWEIATGRCIRTIETEDVVRCVAWCPNAKLSIIAVATGSRLLLVNPKVGDKLLVKKTDDLLAEAPVLDVIENERIKTAVQWANAEPADQEKGVRVIITHFKPIRQVTWHGRGDYLATVMPEGANRSALIHQLSKRRSQIPFSKSKGLIQCVLFHPVKPCFFVATQHNIRIYDLVKQELIKKLLTNSKWISGMSIHPKGDNLLVSTYDKKMLWFDLDLSTKPYQTMRLHRNAVRSVAFHLRYPLFASGSDDQAVIVSHGMVYNDLLQNPLIVPLKKLQTHEKREEFGVLDVNWHPVQPWVFSTGADCTIRLFT
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: RS7_YERPS
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAEAIVYTALETLAQRSGKDFLEAFEVALDNVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVDAARKRGDKSMALRLANELSDAAENKGSAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: UPK1B_RAT
Sequence: MAKDDSTVRCFQGLLIFGHVIVGMCGIALTAECIFFVSDQHSLYPLLEATNNDDIFGAAWIGMFVGICLFCLSVLAIVGIMKSNRKILLAYFIMMFIVYGFEVASCITAATQRDFFTTNLFLKQMLMRYQNNSPPTNDDKWKNSYVTKTWDRLMLQDHCCGVNGPSDWQKYTSAFRVENSDADYPWPRQCCVMDKLQEPLNLDACKLGVPGYYHSQGCYELISGPMDRHAWGVAWFGFAILCWTFWVLLGTMFYWSRIEY
What is the function of this protein?
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells.  May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity).
What are the official names of this protein?
Uroplakin-1b, UP1b, Uroplakin Ib, UPIb.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL33_ECO81
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: METE_SALG2
Sequence: MTILTHTLGFPRVGLRRELKKAQESYWAGNSTREALLAVGRELRARHWEQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNNDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYIVPEFSKGQQFRLTWTQLLEEVDEALALGHKIKPVLLGPVTYLWLGKVKGEPFDRLTLLTDILPVYQHVLAELAKRGVEWVQIDEPALVLELPQAWLDAFKPAYDALAGQVKLLLTTYFEGVTPNLDTIIALPVQGLHVDLIHGKDDVAELHQRLPVDWLLSAGLINGRNVWRADLTEKYAQINAIVGKRALWVASSCSLLHSPIDLSVETRLDTEVKSWFAFALQKCGELALLRDALNSGETAALEEWSAPIQARRHSRRVHNAAVEKRLAAITAQASQRENPYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRGLRLDFKKGNLDANNYRTGIAEHIKQAIIEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTHNGWVQSYGSRCVKPPVVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVTRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLEWGVEAFRINAAVAKDETQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEAFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAQRIPAQRLWVNPDCGLKTRGWPETRAALANMVKAAHNLRQAK
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: ABHEB_HUMAN
Sequence: MAASVEQREGTIQVQGQALFFREALPGSGQARFSVLLLHGIRFSSETWQNLGTLHRLAQAGYRAVAIDLPGLGHSKEAAAPAPIGELAPGSFLAAVVDALELGPPVVISPSLSGMYSLPFLTAPGSQLPGFVPVAPICTDKINAANYASVKTPALIVYGDQDPMGQTSFEHLKQLPNHRVLIMKGAGHPCYLDKPEEWHTGLLDFLQGLQ
What is the function of this protein?
Acts as an atypical protein-lysine deacetylase in vitro (PubMed:31478652).  Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues (PubMed:31478652).  Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo (Probable).  Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate (PubMed:31478652, PubMed:14672934).  May activate transcription (PubMed:14672934).
What are the official names of this protein?
Putative protein-lysine deacylase ABHD14B, Alpha/beta hydrolase domain-containing protein 14B, Abhydrolase domain-containing protein 14B, CCG1-interacting factor B.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD14 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: GCSP_PROMH
Sequence: MTQTLTQLEYRDEFIRRHIGSSPEQIKEMLDVVGISSLNELTQKIVPDNIQLATPPNVGGGATEQEALAELKAIARKNKRFTSYIGMGYAPSVLPPVILRNLLENPGWYTAYTPYQPEVSQGRLESLLNFQQVTIDYTGMDLASASLLDEATAAAEAMAMAKRVSKLKNAERFFVADDIHPQTLDVVKTRANTFGFEVIVDKAEKVLELEGVFGVLLQQVGTTGEIHDYSQLISELKTRKIITSVAADLMALVLLTAPGQQGADIVLGSAQRFGVPMGYGGPHAAFFACRDEYKRAMPGRIIGVSRDAAGNRALRMAMQTREQHIRREKANSNICTSQVLLANIAAMYAVYHGPEGLKNIAQRIHRLTDILAAGLIQNGMTLRHQTWFDTLTVETADKAGVLQRAKDAEINLRTDIVGAVGVTLSEVTTREDVVRLIEIISGKAFSDDIDTLDALVASSSTSIPTAMLRKDAVLTHENFHLYHSETEMMRYMHRLENKDLALNQAMIPLGSCTMKLNAAAEMLPITWPEFTEMHPFCPPYQAQGYQIMIEQLSNWLAAITGYDAMCMQPNSGAQGEYAGLLAIRRYHQSRGEGNRHICLIPSSAHGTNPASAHMAGMTVVVVGCDENGNIDIADLKAKAEKHQAELSCVMVTYPSTHGVYEEGIREVCEIIHQYGGQVYLDGANMNAQVGITTPGFIGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVEMDGVTTQGAVSAAQFGSASILPISWMYIRMMGSEGLKQASQVAILNANYIAQRLKDDYDILYSGAEGYVAHECIIDIRPLKANYGISEMDVAKRLIDYGFHAPTMSFPVAGTLMIEPTESESKVEIDRFIDALLSIRAEIAQVDDGVWPIDDNPLVNAPHTQYELVQEWSHSYSRECAVFPSEATKRNKYWPAVKRLDDVYGDRHLHCSCAPISDYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: CYB_AKAMU
Sequence: MRILKSHPLLKLLNAYIIDHSQPTNINYLWNFGSLLGLCLGIQIITGVTLAMHYNPSVAEAFNSVEHIMRDVNNGWLIRYLHSNTASAFFFLVYLHIGRGFYYGSYRSPRTLAWILGVIILILMMGIGFLGYVLPYGQMSLWGATVITNLISAIPWIGQDIVEFIWGGFSVNNATLNRFFALHFVLPFVLAALVIMHLIAVHETAGASNPLGTPAYYDRIPFAPYYLFKDLITIFLFMFGLSIFVFFMPNVLGDSENYIMANPMQTPAAIVPEWYLLPFYAILRSIPNKLLGVIAMFASLVILMVLPKTDLGITKGLQFRPLSKIAFYLFVTNFLLLLQLGAKHVESPFIEFGQISTALYFAYYLIIMPGVSILENTLIDLSQKG
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.