PharMolix/UniProtQA huggingface dataset:
Protein: MOAA_ACTP7
Sequence: MQSIPIKNVGADNVSQLIDRFERQYVYLRLSVTDVCNFRCNYCLPDGYKPPSHKQQFLSVSEIQRVVRAFADLGTEKVRITGGEPTLRKDFLEIAHTVSQTNGIKKVALTTNGYRMERDIDLWQQAGITDINVSVDSLDTRQFQLITGENKLQSILKGIDRAFEIGYRKIKVNAVLMKQYTAPELDKFLVWIKDKPIQMRFIELMETGEMDSFFQAQHLSGQSVMQRLLQEGWQLQPKALSDGPAKVLSHPDYQGEIGLIMPYEKNFCASCNRLRVSALGKLHLCLFGEEGIDLRDLLSEDTQQAQLEARLKAALQGKREHHYLHIGDSGIRNNLASIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: SHE10_YEAS8
Sequence: MGKLIKLITTLTVLVSLLQYCCEFNSGSISCERTQTLCHYTNPRVWNTYFSRNCELYKNKVSPGFDIVARKYDTAVKPVIDDATVKVNKAAIQPAFKVIHSQCKKWNCGKYYQLVRSPMVKTRRFFFAKYNAFVKPNLDKFFTAEFRSHLKERILKYKNIGHYYFTITSRCIKSKYDFTVGNTEEKLMGKFKNKDTHGIHGSVTREPSSEDMVLTVSTMESDEEELTTTSTQTVVETITLDQEEASAVANHAHDDEASTDVEGSTDVNVNEQALLQEDFDMWSETILQKTQDVIQLFEKDVSKYINGKLVEEANHFKAKFQSLDDKSKKFFSKISLAINDIECVEGIDSETGKKIFFDKSGSTEISQYITRELVREYFNETRSTLDELTNAMEKDLSEITDEIEKKVNAIREENVEVFEEWGDIIVNEWSKRMAYVDVINAHMGADDDTTLDEEKAKSSVNWKKFLKGKKQIIESRDKLAHHSADLSRVNAFRQKVQKKILSFTQESGEFLYILRSKANLQFQERERKERERKEREKAAAEEFQRQQELLRQQEEEDEEDVSYTSTSTITTTTTMTL
What is the function of this protein?
Involved in spore wall assembly.  May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria.
What are the official names of this protein?
Outer spore wall assembly protein SHE10, Sensitivity to high expression protein 10.
What is the protein family that this protein belongs to?
Belongs to the SHE10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RLMH_THESQ
Sequence: MKVRIAVVGKLDGFIKEGIKHYEKFLRRFCKLEVLEIKRVHRGSIEEIVRKETEDLANRILLGSFVMVMDRRGEEVSSEEFADFLKDLEMKGKDITILIGGPHGLNEEIFAKAHRVFSLSKMTFTHGMTVLIVLEQIFRAFKIIHGENYHY
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_NEIMB
Sequence: MNPSPLLDLIDSPQDLRRLDKKQLPRLAGELRTFLLESVGQTGGHFASNLGAVELTIALHYVYDTPEDKLVWDVGHQSYPHKILTGRKNQMHTMRQYGGLAGFPKRCESEYDAFGVGHSSTSIGAALGMAAADKLLGSDRRSVAIIGDGAMTAGQAFEALNCAGDMDVDLLVVLNDNEMSISPNVGALPKYLASNVVRDMHGLLSTVKAQTGKVLDKIPGAMEFAQKVEHKIKTLAEEAEHAKQSLSLFENFGFRYTGPVDGHNVENLVDVLKDLRSRKGPQLLHVITKKGNGYKLAENDPVKYHAVANLPKESAAQMPSEKEPKPAAKPTYTQVFGKWLCDRAAADSRLVAITPAMREGSGLVEFEQRFPDRYFDVGIAEQHAVTFAGGLACEGMKPVVAIYSTFLQRAYDQLVHDIALQNLPVLFAVDRAGIVGADGPTHAGLYDLSFLRCVPNMIVAAPSDENECRLLLSTCYQADAPAAVRYPRGTGTGAPVSDGMETVEIGKGIIRREGEKTAFIAFGSMVAPALAVAEKLNATVADMRFVKPIDEELIVRLARSHDRIVTLEENAEQGGAGGAVLEVLAKHGICKPVLLLGVADTVTGHGDPKKLLDDLGLSAEAVERRVRAWLSDRDAAN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: CYB_ERYCC
Sequence: MPHQQILILFGLLPVATNISTWWNFGSMLLACSSMQVLTGFFLAVHYTANINLAFSSIMHITRDVPYGWMMQNLHAIGASMFFICIYTHIARGLYYGSYLNKKTWLSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTMTTWLWGGFAINDPTLTRFFALHFILPFGIISLSSLHIMLLHEDGSSNPLGTNSDIDKIPFHPYHTYKDMLMLSLMILALLMTVAFFPDIFNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALVMSIMILLTAPFTHTSAIRSMTFRPIMQLMFWTLVATFAVITWAATKPVEPPFTTISQVASTMYFMFFITNPIMGWFENKIMKYN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: QUEA_YERPG
Sequence: MRVADFSFELPEALIAHYPQPQRSGCRLLSLDGPTGTLTHGIFTDLLDKLAPGDLLVFNNTRVIPARLFGRKASGGKLEVLVERVLDDHRVLAHVKASKAPKPGAELLLGDDESIRATMLARHDTLFELRFDDERDVFTILNAVGHMPLPPYIDRPDEDADRELYQTVYSQRPGAVAAPTAGLHFDEPMLAALQEKGIEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQEVVDAVLACKARGKRVVAVGTTSVRSLESAAKAAENGLIAPFFGDTRIFIYPGYHYQVVDALVTNFHLPESTLIMLVSAFAGYKNTMNAYQQAVAEQYRFFSYGDAMFISRNPRAPQEKVSP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_GEOKA
Sequence: MNQEVIAKRYASALFQIALEQGQLDRIEEDVRAVRQALAENGEFLSLLSYPKLSLDQKKALIREAFAGVSTPVQNTLLLLLERHRFGLVPELAEQFLALVDDARGIAKAVAYSARPLTDEELRALSDVFAQKVGKQTLEIENIIDPELIGGVKLRIGNRIYDGSVSGQLERIRRQLIG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RIBL_METFA
Sequence: MVKKRVVTAGTFDILHPGHYEVLKFAKSLGDELIVIVARDETVKKIKGRKPIIPEEQRREMVEALKPVDKAILGSLKNKLEPILELKPDVIVLGPDQTTFDEETLKEELAKYGLHPEIVRFKGYKKCPFHSSFDIVKEIIRRFCNKEIKI
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: IDI2_STAAE
Sequence: MSDFQREQRKNEHVEIAMAQSDAMHSDFDKMRFVHHSIPSINVNDIDLTSQTPDLTMAYPVYINAMTGGSEWTKNINEKLAVVARETGLAMAVGSTHAALRNPRMAETFTIARKMNPEGMIFSNVGADVPVEKALEAVELLEAQALQIHVNSPQELVMPEGNREFVTWLDNIASIVSRVSVPVIIKEVGFGMSKELMHDLQQIGVKYVDVSGKGGTNFVDIENERRANKDMDYLSSWGQSTVESLLETTAYQSEISVFASGGLRTPLDAIKSLALGAKATGMSRPFLNQVENNGIAHTVAYVESFIEHMKSIMTMLDAKNIDDLTQKQIVFSPEILSWIEQRNLNIHRG
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_DESOH
Sequence: MFRGTSYHRIDPKGRIVIPSRFRDLIGADGTAMITFFEGGLYAYTLEEWSKIEAKMVMLEKKGNQMRRFRRFFIGRASECQPDKQWRLLIPPELRQDAGLEEEIVLIGISDHFEIWSRAKWEEQKNLHEDDMNDEDFQNEIEKLGL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYR_RUTMC
Sequence: MKEQLQKILKQSLNLLENEGVLESAPENIRIDHTKDKTQGDFASNIAMVLAKRSGLIPKVLAQKIIDNLGDNTQIDKVQIADPGFINFFISQGESVQIIEQIINQAEHYGKADVGKGQRILLEFVSANPTGPLHVGHGRVAAYGATVASLLRAVGFEVDNEYYVNDAGRQMDILAISVYLRYVETEQFPDNGYKGDYIFDIAKKISGVKKLDIFISQRSVKKNAGNKEKHIDRLIANCKFQLGHDYKKILDLAINNILSGIKIDLVEFGVKYQQWFSEQSLMDSGLSKEIVKKLQDSGYIYEKEGALWFKTTDFGDDLDRVVVRKNGKYTYFASDIAYHLEKFERGYDKIINIWGVDHHGYIARIKASIKALNHNSNKLEILLVQFVNLFRNGKKASMSTRSGSFITLEELREEVGNDAARFFYILSKSGQHMNFDLDLAKSKSNENPVFYIQYAHARICSVLKQAKSPSMVDIDLSVLNNESEALLIKELNRYKDILQSSALNYEPHVLACYLRELAGHFHSYYNNSKFLVDDDKLRNARLFLIIAVKQILVNGLNLLGVSAPDSM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REQU_MOUSE
Sequence: MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKRHRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLEALLRTDPLEKRGAPDPRVDDDSLGEFPVSNSRARKRIIEPDDFLDDLDDEDYEEDTPKRRGKGKSKSKGVSSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGEDKEDSRPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNLCGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCLDLLKEKASIYQNQNSS
What is the function of this protein?
Plays an active role in transcriptional regulation by binding modified histones H3 and H4.  Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (By similarity).  Might also have a role in the development and maturation of lymphoid cells (PubMed:7961935).  Involved in the regulation of non-canonical NF-kappa-B pathway (By similarity).
What are the official names of this protein?
Zinc finger protein ubi-d4, Apoptosis response zinc finger protein, BRG1-associated factor 45D, BAF45D, D4, zinc and double PHD fingers family 2, Protein requiem.
What is the protein family that this protein belongs to?
Belongs to the requiem/DPF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: YEGS_SALPA
Sequence: MANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVETVIAGGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATSAGIPEALDKALKLAIAGNAMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALGGVSYLIHGLMRMDTLTPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPTALVNDGLLQLRIFTGEELLPALFSTLTQSDDNPNIIDGASAWFDIHAPHEITFNLDGEPLSGQEFHIEVLPGALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLA1_ECOLX
Sequence: MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
What are the official names of this protein?
Beta-lactamase SHV-1, PIT-2.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: AT1B3_CHICK
Sequence: MSKETKKPFRQSVAEWRQFVYNPNSGEFLGRTAKSWGLILLFYLVFYGFLAALFTFTMWVMLQTLSNDIPKYRDRISSPGLMISPKPDTALEFYFNKSDAQSYAEYVSTLRKFLETYDDSKQSQNINCTPGKVFDQNDVAVKKACRFNLSELGQCSGKEDKTFGYSKGTPCVLVKMNRIIGLKPEGEPYIQCTSKEPGAVEINYFPSGGLIDLMYFPYYGKTLHAHYLQPLVAVQLAINSNSTNEEIAIECKILGSPNLKNEDDRDKFLGRIAFKVEMTE
What is the function of this protein?
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.  The exact function of the beta-3 subunit is not known.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-3, Sodium/potassium-dependent ATPase subunit beta-3.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: GFRP_XENTR
Sequence: MPYVLISTQIRMETGPTIVGDEFSDTQLMAQLEADKRTVLGNNFSEYCVNEPPRVTLNKLEKLGYRVVSMTGVGQTLVWCLHKE
What is the function of this protein?
Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1.
What are the official names of this protein?
GTP cyclohydrolase 1 feedback regulatory protein, GFRP, GTP cyclohydrolase I feedback regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the GFRP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus membrane. Cytoplasm, cytosol.
Protein: ILVD_PARD8
Sequence: MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFTQFVPGHTHLHEIGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADSVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLIDAMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATHKNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLHLLAVAQEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAGLVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELDTDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDAACEGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKKAFTPPTRQREVSKALRAYGKMVSSADKGGVRIVED
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RL9_OENOB
Sequence: MKVIFLQDVKNQGKRGQIKEVPDGYANNFLIKNKKAVYASPENISKLNGQQNLEAKKAAEILEEAKQLKNKLASTKTIVQFSEHVGPDGRLNGSVTAKEIADQLAKQFNLTVDKRKLQLPQPIKTIGLHEVPAKLHTQVSAMIKVNVSELN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GREA_BARHE
Sequence: MEKVPMTTAGFESLKEELRWRQQEERPRIIEAISEARAHGDLSGNAEYHAAKEAQSHNEGRINELEDYIARAEVINVSRLSGDKIKFGATIKLLDEDTEEKKVYQIVGDQEADVKTGKISISSPIARALIGKQEGDVIEVNAPGGAHNYEIIEVQYI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RL10_SHESM
Sequence: MALRLEDKKAIVAEVNEAAKGALSAVAADSRGVTVGAMTGLRKKAREAGVYVRVVRNTLARRAVEGTAFECLAETFTGPTLIAFSNEHPGAAARLLKDFAKEQANFEVKGAAFEGNFIPAADIDRLAKLPTYEEALAQLMMTMKEASAGKFVRTLAALRDQKQEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GLNE_RHIME
Sequence: MAEAIERSLSDIDVVAIRPASQADAKAALSVLKDAAKGSDHIAKLIASDAPLKDFLVAAFALSPFLRDTARSHPAILEALLSETLPAFLKRRIEAARVAWRGDAAGAALPDAEIMTRLRRAKREVAFAVALADLSRLFGGRETTGWLSDFAEAAVSAAIDHLLLGAHESGKFVLKDSSAPSTASGVVVLGMGKLGAGELNYSSDIDLVVFYDPQSSIITNRDDAPETFARLLRRLIRILQERTGDGYVFRTDLRLRPDPGSTPLAIPVEAAMLYYESRGQNWERAAFIKARPIAGDLEAGERFLKELTPFVFRKYLDYAAIADIHSIKRQIHAHKGHGEIAVKGHNIKLGRGGIREIEFFVQTQQLIAGGRTPALRLRQTETMLRMLAESGWIDGATAEELIEAYWFLRDVEHRIQMVHDEQTHLLPETEPELRRIAYMLGFEDTASFSNALSRVLRTVERRYAQLFEQEAKLSTETGNLVFTGQQDDPDTLETLKKLGFQRPSDIANIIRTWHYGRYRATQSVEARERLTELTPELLRVFGESRRADEAFLRFDHFLSGLPAGIQLFSLLGNNPGLLSLIVNIMSSAPRLADIIAAKPHVFDGMLEPGLLAELPTRDYLAPRIATFVGGGRHYEEVLDRLRIIAAEQRFLIGIRLLTGAITGLQAGRALTDLADLIIAAALDAVLEEVRSAHGRFPGGRVAIVGMGKLGSHELTAGSDIDLILLYDYDDEVLESDGAKPLDPVRYFTRVTQRLIAALSAPTAEGILYDVDMRLRPSGNKGPVATRITAFAKYQRTEAWTWEHLALTRARCICGDESLVGEAEAIFAEILTEKRDIAKIRKDVEEMRGLIDKEKPPKDIWDFKLIPGGLVDIEFIAQYLALVAPARGVTSPPAGTHTLEALKALGAGMMNANDLDTAAEALVLFTELSQLVRLCIDGDFDPKEAPAGLVDLVCRAGDYPDLTHLEADIRRLSKAVRRIFQGVVAAA
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: G6PI_FRATN
Sequence: MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINDYILKSLLESAEKSSLKDKIKQMFNGAKINSTEHRAVLHTALRDLSSTPLVVDGQDIRQEVTKEKQRVKELVEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQPYHCTDLKVHFVSNVDADSLLQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDKVKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKETEFSKNIPVIMALLASYYSCTYNSQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGETVNYQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATSHHNYDNHQQALLANCFAQSQALMFGQSYDMVYNELLKSGLNETQAKELAAHKVIPGNRPSTTILLDELSPYSLGALIALYEHKIFVQGVLWDINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKSK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_PSE14
Sequence: MNAPHKTGTGRRAIPAAVDIDALIRAEHRDPFSILGPHGDGGSGQYVRAYLPAALSVRLLAKDDGRELGEMEMSEVPGFFVGHLEQPQPYLLKVQWAGGEQITEDPYSFGPLLGEMDLYLFAEGNHRDLSSCLGAQVTKVDGVDGVRFAVWAPNARRVSVVGSFNSWDGRRHPMRLRHPTGVWEIFVPRLQPGEVYKYEILGAHGILPLKSDPMALATTLPPDTASKVSAPLQFEWNDQEWLRSRTGRHDVAAPLSIYELHAGSWQMEQHEDGQWRQYNWRELADRLIPYVKELGFTHIELMPIMEHPFGGSWGYQLLAQFAPTARYGSPEDFAAFVDACHRAEIGVILDWVPAHFPTDTHGLAQFDGTALYEYADPKEGFHQDWNTLIYNLGRTEVHGFMLASALHWLKHYHIDGLRVDAVASMLYRDYSRNAGEWVPNRFGGRENIETIDFLRHLNDVVALEAPGTMVIAEESTAWPGVSEPTQQGGLGFNYKWNMGWMHDSLQYMMRDPLHRRHHHSTLTFGLVYAWSERFVLPISHDEVVHGKHSLIDKMPGDRWQKFANLRAYLSFMWTHPGKKLLFMGCEFGQWREWNHDEQLDWYLMQYADHVGVKNLVGDLNRLYRQEKALHQRDADPAGFQWLIGDDQANSVFAYLRWSNDGEPLLVVANMTPVPRLAYRVGAPVSGAWTELLNSDAETYAGSNMGNGGEVNTEDEPAHGMEASLKLNLPPLAVLILKPKKD
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: HOG1_COCIM
Sequence: MAEFVRAQIFGTTFEITTRYTDLQPVGMGAFGLVCSARDQLTNQAVAVKKIMKPFSTPVLAKRTYRELKLLKHLRHENVISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLARVQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDVWSAGCIFAEMLSGRPLFPGKDHVNQFSIITELLGSPPDDVIKTICSANTLQFVQSLPKRERQPLSEKFKGAEPLAVDLLERMLVFDPKKRITAAEGLAHEYLAPYHDPTDEPVAETQFDWSFNDAELPIDSWKVMMYSEILDYHNVDQDSQGIHGTPLNTEAQRVPM
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase HOG1, MAP kinase HOG1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLMM_MYCBP
Sequence: MGRLFGTDGVRGVANRELTAELALALGAAAARRLSRSGAPGRRVAVLGRDPRASGEMLEAAVIAGLTSEGVDALRVGVLPTPAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHKLDDDTEDQIEDLVLGVSRGPGLRPAGAGIGRVIDAEDATERYLRHVAKAATARLDDLAVVVDCAHGAASSAAPRAYRAAGARVIAINAEPNGRNINDGCGSTHLDPLRAAVLAHRADLGLAHDGDADRCLAVDANGDLVDGDAIMVVLALAMKEAGELACNTLVATVMSNLGLHLAMRSAGVTVRTTAVGDRYVLEELRAGDYSLGGEQSGHIVMPALGSTGDGIVTGLRLMTRMVQTGSSLSDLASAMRTLPQVLINVEVVDKATAAAAPSVRTAVEQAAAELGDTGRILLRPSGTEPMIRVMVEAADEGVAQRLAATVADAVSTAR
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SYT_SHESH
Sequence: MPVITLPDGSKREFANPVSTLDVAADIGPGLAKACIAGRVNGELKDACDIIDTDSELSIITAKDEEGVEILRHSCAHLLGHAFKQLWPEAKMAIGPVIDNGFYYDIDLDHKLTQEDIDALQKRMTQLAKTNYKVEKRVGSWQVARDTFEARGETYKMEVLDENISKDDQPALYHHEEYVDMCRGPHVPNMKFCQNFKLMSVAGAYWRGNSDNKMLQRVYGTAWADKKALKVHLNRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWSLFLELEKFIRQKLGQYTYQEVKGPLMMDRVLWERSGHWDKYADAMFTTNSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGCCHRNEPSGSLHGLMRVRGFTQDDAHVFCTEDQVQQEVSACIKMVYDTYETFGFKDIVVKLSTRPEKRIGDDDMWDRSEEALKQALTANGIAYEILPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDYALPGRLGATYVAEDNSRQTPVMIHRAILGSLERFLGILIEEYAGKFPTWLAPMQVVVMNITDKQSDYVDEVVNIFKESGIRASKDLRNEKIGFKIREHTLRRVPYLLVVGDQEMDNKEVAVRTRDGVDLGKMRIEDFASKINEQISLRSLNLLED
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.