PharMolix/UniProtQA huggingface dataset:
Protein: RSSA_LEIBR
Sequence: MTAVESGSKVLRMKESDAQKLLAMRCHIGTRNQSSAMKKYIYGRTAEGSHIIDVHMLWEKLILAARVIAAVENPKDVCVCSSRLYGTRAIYKFSQHVGTSFHGGRFIPGTFTNQIQKKFMQPRVLVVTDPRTDHQAIREASLVNIPVIALCDTDAPLDFVDIAIPCNNRGIKSIGMMYWLLAREVLRLRGTIVRSVPWEEKVDLFFYRDPNEAAEEKAAAAAAAPAAEVEEGFGWVERNDDNAWEA
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_CROS8
Sequence: MTSYENHQALHGLTLGKSTDYRDVYDASLLQPVPRSLNRDPLGLRADALPFHGADIWTMYELSWLNRNGLPQVAIGQVEINATSVNLVESKSFKLYLNSFNQTQFESLEAVRETLERDLRACAQGDVSVTLRRLEDVEGEPVARFSGDCIDNQDINITDYEFDAALLSGAAGEETVEETLVSHLLKSNCLITHQPDWGSVQIHYRGPKICREKLLRYLVSFRHHNEFHEQCVERIFNDITRFCQPEQLSVYARYTRRGGLDINPWRSNGDFTPATGRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCNA4_TITDI
Sequence: MKGMIMLISCLMLIDVVVESKNGYIIEPKGCKYSCFWGSSTWCNRECKFKKGSSGYCAWPACWCYGLPDNVKIFDYYNNKCGK
What is the function of this protein?
Inhibits the sodium (Nav) currents in an apparent irreversible manner.  Produces small depolarization and induces repetitive firing in squid axons.  Is specific for arthropods (crickets, triatomides, crabs and squids), but is non-toxic to mice (PubMed:15033324).  Shows antibacterial activity against both Gram-positive and Gram-negative bacteria (By similarity).
What are the official names of this protein?
Ardiscretin, PT-Arthr-beta* NaTx2.1, Toxin TdNa4.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SECA_ECOUT
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSYQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RL14_ROSDO
Sequence: MIQMQTNLDVADNSGARRVQCIKVLGGSKRKYASVGDIIVVSVKEAIPRGRVKKGDVRKAVVVRTAKEVRREDGTAIRFDRNAAVILNNNNEPIGTRIFGPVVRELRAKNFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: APAG_ECO55
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: LDH2_STAAB
Sequence: MKTFGKKVVLIGDGSVGSSYAFAMVTQGVADEFVIIDIAKDKVKADVQDLNHGTVHSPSPVDVKAGEYEDCKDADLVVITAGAPQKPGETRLQLVEKNTKIMKSIVKSVMDSGFDGYFLIAANPVDILTRFVKEYTGLPAERVIGSGTVLDSARLQYLISQELGVAPSSVDASIIGEHGDTELAVWSQANVAGISVYDTLKEQTGSEAKAEEIYVNTRDAAYEIIQAKGSTYYGIALALMRISKAILNNENNVLNVSIQLDGQYGGHKGVYLGVPTLVNQHGAVKIYEMPLSAEEQALFDKSVKTLEDTFDSIKYLLED
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate (Potential).  Contributes to S. aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells, despite playing a secondary role in this resistance mechanism (By similarity).
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_ACIB5
Sequence: MMRTHYCGSLTEAQIDQTVTLCGWVHRRRDHGGVIFLDMRDRDGLVQVVIDPDTPEAFATADKARSEYVLKITGRVRRRYEGTENPNMVSGQIEVLGKEIEVLAASETPPFPLNDDTINVSEEHRLKYRFLDIRRPEMLERLRFRSKVTNLIRNYLDDHGFLDVETPILTRATPEGARDYLVPSRVQNGSFYALPQSPQLFKQLLMVGGIDRYYQIAKCFRDEDLRADRQPEFTQIDIETSFLNDDDIMDLMEGMTVKLFNDLLGVKFEKFRRMPYSEAMRDYASDKPDLRIPLKLVDVADLMQEVEFKVFAGPAKDPKGRIAALRVPGAGSLTRSQIDEYTKFVGIYGAKGLAYIKVNEIEKGIEGLQSPIVKFIEPIVMQLLERVGAENGDIVFFGADKAKIVNDAMGALRVKIGHDLNLATCEWAPLWVVDFPMFEETDDGKWTSVHHPFTLPKSSVEDVKSNPGEALSVAYDMVLNGTEVGGGSLRIYTLEMQKAIFEALGISDEEAEEKFSFLLNALRYGAPPHGGLAFGLDRLVMLMTGATSIRDVIAFPKTKTAECPLTQAPAPVEANQLRDLGIRLREQQKKEA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLN1A_STAEQ
Sequence: MPKRSFTKDDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMFDGSSIEGFVRIEESDMYLHPDLDTWVIFPWTAGQGKVARLICDVFKTDGTPFEGDPRANLKRVLRRMEDMGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFDLAPTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKLVVKTIARKHNLHATFMPKPLFGVNGSGMHFNVSLFKGKENAFFDPEGDLQLTDTAYQFTAGVLKNARGFTAVCNPIVNSYKRLVPGYEAPCYIAWSGKNRSPLVRVPTSRGLSTRIEVRSVDPAANPYMALAAILEAGLDGIENKLEVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKAMRENKSIKNALGNHIYNQFINSKSIEWDYYRTQVSEWEREQYIKQY
What is the function of this protein?
Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism.  It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.  Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA.  During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation.  Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity.  In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_XYLFT
Sequence: MSESSEKTSTTHFGFRQVAAKDKKTLVAEVFTSVSRRYDLMNDLMSLGIHRAWKRYFVATAQVKSGDRVLDLAGGTGDIAMLLKNRVGAEGSIVLGDINASMLSVGRDRLIDRGVVARLDYVQCNAEALPFQDKCFDLVTMSFGLRNVTDKDAALREMFRVLKVGGQARVLEFSAVTAEWFKPIYDFHSFQVLPRLGRLFARDAASYRYLAESIRKHPPQEELQAMMGSAGFERCGYRNLTGGIVAIHSGYKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: VATC_PYRHO
Sequence: MEISTLTTILDTTLAVIFTWVAYKTGQIIWKYTPYSYPNARIRAMEARLLTDQRFSELAESKTLQNFVVSLEDTDYSPRLASLQSYNLYEIERALDLSLVDLVELMIKIMPKRIRGLFEILLEEWDVRNITNVIKAKLSNLPPQDFIIPAGRMFPKVKAMVESKTMEEILVILEGTEYEEPLRKLLLKEIDLQAFELELYKIYYSKLLKYASSRKGEEKLISEEFIKMLIDYRNISIILRAKLSGMPSEEIKSLLIPGGMLSRAVLESMLSSEDVMMALGELEGTRYGDALKDVREAVEGGRIDKVEEALRRYILNRMKELSQFYPLSVAVALTYLLERESEVRKLKAVAKLIEDKAKPEKIKELIGEMA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: UVRC_XANCB
Sequence: MSARPQADFDGKAFAARLSTAPGVYRMYAADDSLLYVGKAGALRKRVGSYFNGTPKNARLTSMLSQVARMDVTVTRSEAEALLLENQLIKSLSPRYNVSLRDDKSYPYVLLTREDWPRIALHRGPRAVNGRYFGPYAGVTAVRETLNLMHKLFKLRSCEDSVFRNRSRPCLQYQIGRCSAPCVDLVAAQDYQEAVRRATMFLEGKSDQLGEEIMHSMQQASEALEFERAARLRDLLSSLRSMQNRQYVDGRAADLDVLACATQSSQACVLLLSFRDGRNLGTRSFFPKTNGEDSAEEILAAFVSQYYAEHAPPREILLDRAIPDAELIEAALSAAAEHKVALKWNVRGERAGYLLLASRNAQLTLVTELTSQSAQHARSEALREMLGLAEQVKRVECFDISHTMGEATVASCVVFDASGPVRGQYRRFNISGITPGDDYAAMRQAIERRFRRAVEENGVLPDVLLIDGGAGQLAQAQAALADLGIENVLLVGVAKGEERRAGHEALILADGRELRPGAASPALQFIQQVRDEAHRFAITGHRGRRQKARMTSKLEDIPGIGPRRRASLLKHFGGLVGLKAAGEAEIARVEGVNAALAARIYANLHGLALPDAAGESSP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4081_VIBA3
Sequence: MKTIQSIALLSAIVAAPSVLADVEIQVPSSVDILAVNEAKPDLDGGLFSSHKTLTLPDGQNQIVFQYQLAFDKGNDREFVDSDAVIATFDATDTTLTFDLPKYRNTAEAKSGFKNLEWSLVDENQNEISVKQDKLVKDGMQIGRKYPQEAKEYNQQGGIAALAIGTTAGATAAVVQPVTLPAKIDGNAANTAEEMLYFWYEKADAETKQKFKDYVNK
What are the official names of this protein?
UPF0319 protein VS_II0881.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: PTH_STRAW
Sequence: MGDTDVTSDANAPWLIVGLGNPGPEYARNRHNVGFMVADLLAERIGGKFKRAGKAQAQVIEGRIGPPGPANRRVILAKPMSYMNLSGGPVNALREFYKVPVANIVAVHDELDIDYGVLRLKLGGGDNGHNGLKSMTKAMGPDYHRVRFGIGRPPGRMQVADFVLKDFASAERKELDYLVDRAADAAECLVIEGLERAQGTYNS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_RUEST
Sequence: MTDRTAAPSGPHIPVLLKPLLAAVAPVTGRWLDGTFGAGGYTKGLLAAGADQVIGVDRDPLAFEMAQPWAAEYGDRLVLQQGVFSRMDEYAQELDGVVLDLGVSSMQLDLAERGFSFMKEGPLDMRMSQDGPSAADLVAELSEVQLADVLYSFGEERASRRIAKAIVKERAQEPITTTLRLAEIIEGCLPRPKPGQSHPATRSFQALRIAVNGEYEELMGGLLAAERALKPGGLLAVVTFHSVEDRMVKRFFQHRANKTGNANRYAPAMEEQPSQFELVTRKAVGPDKDELAQNPRSRSALLRVGRRTDAAPVEITAKELSMPQLKETR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAD1_NAKDE
Sequence: MDSDSGGSSPFVESPHGEEVQVRGDETNNTYGQDQWKFKYEGLLNEWEIQKIQWQKEKYEFEKRQLAAEDRLRNANDEMDILIQRNQDLVYRIEEEERNRINNDEGNDLKGGAGSMDKGKKQEIEELSRRYEADRFEWKTQNEELDLELKSCKSLISKYEQLLMEQSEKINSLRSEVKNKEDQIAELEVVRQKKDHNITNTEEFRNLTTLKDIIKTHDQYALDLEQSNMRQAEELKRLKSLKESATFWRSENEQLQERIRQLEEVEQQYNEVQLEILELKVNISEWDRFLKEKCQPGDTETAEYTPSDFVRDYEILQNDYKVLNDEFEDLKKETQMVKILNDELAMERNQILNLKNEYEKSIINLEKLNYELEQQKTLSFEECKLLRKQLESIKHKSNHEENDSTKDYEVLIDNYKNQTKDLTSELKRMNDELIGSNRDSSAGSKKRKLRTGDSVNVNLAQKLNTMQIENSNLQKEIHKLKAIIDVLEKKIRLLKENKEKRIRILQQRDSPLLKIQFARKQELDLLKDENKELLSLIENVTENNQNRIDTIPLSAYKSLEFQYQQSQENVVKGEKQLSRLKQIYNKKSLEFIDIVNSMLGFRLEFMLDGRVKIYSCYKPDKYLIANLIDNTLKSNLDAIISDWDELLSLWVVERGQLPCFLATITLRLWELNPI
What is the function of this protein?
Central component of the spindle assembly checkpoint.
What are the official names of this protein?
Spindle assembly checkpoint component MAD1, Mitotic arrest deficient protein 1.
What is the protein family that this protein belongs to?
Belongs to the MAD1 family.
Protein: COAD_LACCB
Sequence: MTKKIAVFPGSFDPFTNGHLDTVKRASRLFDEVVVAAMTNTSKKPLFSSEEKLALISESTAGLPNVKAMAAPKRLTVEFARSIGARFMIRGIRNVADFGYEADIATVNHDLDPEIETVFLLADKQYDALSSTIIKEVAAFGGDVHRFVPAPVEAALYAKLGDAHQTK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KA141_MESMA
Sequence: MKIFFAILLILAVCSMAIWTVNGTPFAIKCATDADCSRKCPGNPSCRNGFCACT
What is the function of this protein?
Potential blocker of potassium channels.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 14.1, BmKK1, Toxin Kk1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 14 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HISX_DECAR
Sequence: MVAIKRLATVDADFKAQMDALLAFEAAQDEGIERTVIGILADVKARGDAAVVEYSNKFDRLTASSMADLELSKAEMQKALDGLPADQRQALEAAAHRVRVYHEKQRMEGWSYTEADGTMLGQMITPLDRVGLYVPGGKAAYPSSVLMNAIPAKVAGVKELIMVVPTPGGEHNQLVLAAACLAGVDRVFTIGGAQAVGALAYGTEAVPQVDKIVGPGNAYVACAKRRVFGIVGIDMIAGPSEILVVADGSSDPDWVAMDLFSQAEHDELAQSILICTDAAYIDRVQASIEKLLPTMPRREVIETSLTNRGALILVRDLEEACAIANRVAPEHLELSLADPDPWVAKIHHAGAIFIGHYTSESLGDYCAGPNHVLPTSGSARFSSPLGVYDFQKRTSLIKVSKAGAQTLGKIASTLAHGEGLPAHAKSAEFRLEN
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: DTD_CLOPE
Sequence: MRVVVQRVNKSSVKVDNEIVGSINKGFNVLVGIGKEDTIEDLKYMKDKVLNLRVFEDEEDKMNLSLKDVCGELLLISQFTLYGDCRKGRRPNFMNALGGDEAKKLFDEFVSMCREEGIKVETGVFGAHMVVDIENDGPVTLILDSKKNF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT_RUTRU
Sequence: MDPCDCAKTGTCNCGATCKCTNCQCTTCKKSCCTCCPSGCSKCASGCVCKGNSCGSSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: RPOA_PSEF5
Sequence: MQISVNEFLTPRHIDVQVVSPTRAKITLEPLERGFGHTLGNALRRILLSSMPGCAVVEAEIDGVLHEYSAIEGVQEDVIEILLNLKGLAIKLHGRDEVTLTLSKKGSGVVTAADIQLDHDVEIVNPDHVIANLASNGALNMKLVVARGRGYEPADSRQSDEDESRSIGRLQLDSSFSPVRRIAYVVENARVEQRTNLDKLVIDLETNGTLDPEEAIRRAATILQQQLAAFVDLKGDSEPVVVEQEDEIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLDNWPPASLKKDDKATA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MET23_XENLA
Sequence: MGEENEQRIGERVYEFLRREGKDEQKMRVTIPEVLNCQYGMYVWPCAVVLAQYLWYHRKNLADKRVLEVGAGVSLPGILAAKCGAKVILSDSAEMPQCLENCRRSCKMNNIVGVPVIGLTWGEVSPDLLDLPPIDIILGSDVFYEPKDFEDILLTVRFLMERMPQAEFWTTYQVRSADWSVEALLCKWNLKCTNVPLKTFDADNECLAGSELPGRHTVQMMIITLDRKGAGHTG
What is the function of this protein?
Histone methyltransferase that dimethylates histone H3 at 'Arg-17', forming asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling.
What are the official names of this protein?
Histone-arginine methyltransferase METTL23, Methyltransferase-like protein 23.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: KGUA_NOSS1
Sequence: MMQVLSIQNCATTKENPLSGKLIILTGPSGVGKGTLMRSLLQRHPELYYSVSATTRPPRPGEVNGESYYFVSRSKFEELIAQGEFLESAEFAGNYYGTPREAVLNQVQSGKLVVLEIELAGARQIRTSFPEALSIFILPPSFEELENRIRGRGQDSEEAIARRLQRAKEEIQAADEFDIQIVNDDFEAALQAIEVALFG
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYO5_YEAS7
Sequence: MAILKRGARKKVHQEPAKRSANIKKATFDSSKKKEVGVSDLTLLSKISDEAINENLKKRFLNATIYTYIGHVLISVNPFRDLGIYTDAVMNEYKGKNRLEVPPHVFAIAESMYYNMKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASSTHTESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNNQFEPCAGNITNYLLEKQRVVSQIKNERNFHIFYQFTKGASDAYRQTFGVQKPEQYVYTAAAGCISAETIDDLQDYQETLKAMRVIGLGQEEQDQIFRMLAAILWIGNVSFIENEEGNAQVRDTSVTDFVAYLLQIDSQLLIKSLVERIMETNHGMKRGSVYHVPLNIVQADAVRDALAKAIYNNLFDWIVSRVNKSLQAFPGAEKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKSEQETYEREKIQWTPIKYFDNKVVCDLIEARRPPGIFAAMNDSVATAHADSNAADQAFAQRLNLFTTNPHFDLRSNKFVIKHYAGDVTYDIDGITDKNKDQLQKDLVELIGTTTNTFLATIFPDTVDRESKRRPPTAGDKIIKSANDLVETLSKAQPSYIRTIKPNETKSPNDYDDRQVLHQIKYLGLQENVRIRRAGFAYRQVFEKFVERFYLLSPHCSYAGDYTWQGDTLDAVKYILQDSSIPQQEYQLGVTSVFIKTPETLFALEHMRDRYWHNMAARIQRAWRRFLQRRIDAATKIQRTIRERKEGNKYEKLRDYGTKVLGGRKERRSMSLLGYRAFMGDYLSCNESKSKGAYIKRQVSIKEKVIFSIHGEALHTKFGRSAQRLKKTFLLTPTTLYIVGQTLVQNAMTYTQDYKIDVRNIQAVSLTNLQDDWVAIKLASSGQPDPLINTYFKTELITHLKRLNDKIQIKIGSAIEYQKKPGKLHSVKCQINESAPKYGDIYKSSTISVRRGNPPNSQVHKKPRKKSSISSGYHASSSQATRRPVSIAAAQHVPTAPASRHSKKPAPPPPGMQNKAATRRSVPNPASTLTASQSNARPSPPTAATRATPAATPAAAAMGSGRQANIPPPPPPPPPSSKPKEPMFEAAYDFPGSGSPSELPLKKGDVIYITREEPSGWSLGKLLDGSKEGWVPTAYMKPHSGNNNIPTPPQNRDVPKPVLNSVQHDNTSANVIPAAAQASLGDGLANALAARANKMRLESDDEEANEDEEEDDW
What is the function of this protein?
One of two redundant type-I myosins implicated in the organization of the actin cytoskeleton.  Required for proper actin cytoskeleton polarization and for the internalization step in endocytosis.  At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly.  Functions redundantly with LAS17 as actin nucleation-promoting factor (NPF) for the Arp2/3 complex.  Motor domain phosphorylation by PAK kinases CLA4 and STE20 promotes CDC42-regulated actin assembly.  Functions together with the NPF PAN1 in late stages of endocytosis.  Motor domain phosphorylation by PDK1 kinases PKH1 and PKH2, and by SGK kinases YPK1 and YPK2, promotes ligand-induced, but not constitutive endocytosis of the G protein-coupled receptor STE2 (By similarity).
What are the official names of this protein?
Myosin-5, Actin-dependent myosin-I MYO5, Class I unconventional myosin MYO5, Type I myosin MYO5.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Localizes to cortical patch-like protein structures that assemble actin patches. Enriched at sites of polarized growth (By similarity).
Protein: RPOZ_YERP3
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQIQSGGKDALVPEENDKVTVIALREIEEGLITNQILDVRERQEQQEQEAAEIQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RS18_MYCPU
Sequence: MNHNKDKLKKKNKRKRVSFLDEQGINYIDYKDVELLSKFINSHGKILPSKITDVSAKRQRMLTRAIKRARNMALLPFTQERVRTQKPLIVTSNSPKEKEAKPSAQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.