PharMolix/UniProtQA huggingface dataset:
Protein: HEM3_CAMJE
Sequence: MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTKELEESMLRKEAHLAVHSLKDVPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAKIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDFDAIILAMAGIKRLNLDKQVNFVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQVPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELLKKAESMI
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: TRUA_STRGC
Sequence: MTRYKAIISYDGHDFAGFQRQPHARSVQEEIEKTLTRINKGQPVVIHGAGRTDSGVHALGQVLHFDLPEERDGEKLRFALDTQTPEDIDFISVEQVSDDFHSRYNKHSKTYEFLVDIGRPKNPMMRHYATHYPYPLELSLLEEAITQLEGTHDFTGFTASGTSVEDKVRTITEAKVRYDAERNFLVFTFSGNGFLYKQIRNMVGTLLKIGNKRMPVEQIQRILAEKDRHLAGPTAGPNGLYLKEIRYEE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: GARL_SALNS
Sequence: MNNAIFPNKFKAALAAQQVQIGCWSALASPITTEVLGLAGFDWLVLDGEHAPNDVTTLIPQLMALKGSASAPVVRVPTNEPVIIKRMLDIGFYNFLIPFVETQEEAARAVASTRYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITIIVQIESQLGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQQTIQHIFARAKAHGKPCGILAPVEADARRYLEWGATFVAVGSDLGAFRASTQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: PROB_BACHK
Sequence: MKKQRIVVKIGSSSLADSHEGISKEQLSDHVAALARLKEEGHEVLLITSGAVAAGFSALGYPSRPVTIKGKQAAAAVGQSLLMQAYTEEFRKYGIVTAQLLLTRSDFSRKEQYSNAYATLGELLNRSALPIINENDSISLEELTFGDNDMLSALVSGLVSADMLMIFTDVNGLYDKNPQKNEDAKKYYFLPEVTEEIASLAGDAGSKLGTGGMKSKIDAAKTALSLGVSVFIGTGRGQEKFVDVLKGKGDGTYVGNAPQKEMKMNKQWIALHSVVSGQIEIDAGAATAIIQHGKSLLPAGVTNVSGFFQVGEVVEVMTQQGRVIGKGQCTYSAEELRDVKGMQSQHIQARGERHSYEVIHRDHWVSL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRD7_MOUSE
Sequence: MGKKHKKHKSDRHFYEEYVEKPLKLVLKVGGSEVTELSTGSSGHDSSLFEDRSDHDKHKDRKRKKRKKGEKQAPGEEKGRKRRRVKEDKKKRDRDRAENEVDRDLQCHVPIRLDLPPEKPLTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFSTMKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSLKQSIDFMSDLQKTRKQKERTDACQSGEDSGCWQREREDSGDAETQAFRSPAKDNKRKDKDVLEDKWRSSNSEREHEQIERVVQESGGKLTRRLANSQCEFERRKPDGTTTLGLLHPVDPIVGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNRVTPVLYLNYGPYSSYAPHYDSTFANISKDDSDLIYSTYGEDSDLPNNFSISEFLATCQDYPYVMADSLLDVLTKGGHSRSLQDLDMSSPEDEGQTRALDTAKEAEITQIEPTGRLESSSQDRLTALQAVTTFGAPAEVFDSEEAEVFQRKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMYLAEQVTNNLKELTQQVTPGDVVSIHGVRKAMGISVPSPIVGNSFVDLTGECEEPKETSTAECGPDAS
What is the function of this protein?
Acts both as coactivator and as corepressor.  May play a role in chromatin remodeling.  Transcriptional corepressor that down-regulates the expression of target genes.  Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac).  Binds to the ESR1 promoter.  Recruits BRCA1 and POU2F1 to the ESR1 promoter.  Coactivator for TP53-mediated activation of transcription of a set of target genes.  Required for TP53-mediated cell-cycle arrest in response to oncogene activation.  Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters.  Inhibits cell cycle progression from G1 to S phase (By similarity).  Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity.  Induces dephosphorylation of GSK3B at 'Tyr-216'.  Down-regulates TRIM24-mediated activation of transcriptional activation by AR.
What are the official names of this protein?
Bromodomain-containing protein 7, 75 kDa bromodomain protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPF_BACFR
Sequence: MARAIQFTKMHGTGNDYIYVNTLRFPIARPEKAAIEWSAYHTGIGSDGLVLIGHSDKADFSMRIFNADGSEAMMCGNASRCIGKYLYEYGLTSKNVITLDTLSGIKILELHLEGRTVETVTVDMGVPLETDTIDFDGEFPFLSTQVSMGNPHLVTFVDDIRIVNLSEMGPKLEKHPLFPDRTNVEFAQITGENTIRMRVWERGSGITQACGTGACATAVAAHLTGRTGRTVNVVMDGGTLTIEWDEATGHISMTGPAVKVFDGTIELRE
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADA_ECOLI
Sequence: MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPMVARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGGNPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIEQICLIAEEEQPKLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMVGHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQGLREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLEQNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQDLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKAPEGMQIFGVKKLSDALSVFDDL
What is the function of this protein?
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks.  Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster.  Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB.  Does not have RecA's homology-searching function (PubMed:26845522).  Genetic experiments involving combination of radA mutations with mutations in recA, recB, recG, recJ, recQ, ruvA and ruvC show it plays a role in recombination and recombinational repair, probably involving stabilizing or processing branched DNA or blocked replication forks.  Is genetically synergistic to RecG and RuvABC (PubMed:12446634, PubMed:25484163).  May be involved in recovery of genetic rearrangements during replication fork breakdown (PubMed:16904387).  In combination with RadD is important in recovery from double-strand DNA breaks (DSB) (PubMed:25425430).
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA, DNA repair protein Sms.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: NUDC_MANSM
Sequence: MQLIRSSDYGFWLLSQGSHIHLVNNYLPEGRAEDFHLQGKKGMVIGELDRQPLWLVEEQPNDTRAYFDLRDQLYLPERTFNLLNRGVELNHFFKTHQFCGKCGDKTMQTEDEWAVQCTNEECNYRTYPVICPSIIVAIRRGKEILLANHRRHAPKYGKGGMYTTLAGFVEVGESFEQTIHREVFEETGIKVKNIRYFGSQPWAFPNSQMVGFLADYESGEIRLQEEEIADAKWFRYDEPYPEFPEKGTIARALIEATLKLCAEHQDK
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: ATP4_MAIZE
Sequence: MASLPLCRSPSSLLPSWPHRPISASFNPKNPSSPVAAHVSVQETPPQPQDPSPPSDSNPNGTRPSSSSNTRFLWVNPNSPRAADVARARAGSGRRARLASAAAALGACETTESAVEAALQAAFPEPPSEQDAVIVLNTAAATRAETAVLALRWFLGNAKVRKKVILYNVVLKLLRKKRLWSETEALWAEMLRDGVQPDNATFSTVISCARACGLHSKAVEWFDKMPEFGCSPDMLTYSAVIDAYGHAGNSEAALRLYDRARAEKWQLDPVICSTVIKVHSTSGNFDGALNVFEEMKAIGVRPNLVVYNTMLDAMGRALRPWVVKTIHREMVDQQVQPSRATYCCLLHAYTRARYGEDAMAVYRLMKDEAMGIDVMLYNMLLSMCADIGYVDEAEEIFRDMKASMGAHSKPDSWSYSSMVTLYSSTANVLSAEGILNEMVEAGFKPNIFVLTSLIRCYGKVGRTDDVVRSFGMLQDLGIIPDDRFCGCLLSVAANTPAEELGKVISCIERSNVQLGAVVKLLVDRSSSESFREAARELLRSSRGVVKMPYCNCLMDLCVNLNQMEKACALLDAAQQLGIYANIQTRTQTQWSLHLRGLSVGAALTTLHVWMNDLYTSLQTGNEGLPPLLGIHTGQGKNTYSDRGLAAMFEAHLKELDAPFHEAPDKAGWFLTTNVAAKQWLESKAASELVTV
What is the function of this protein?
Involved in translation and accumulation of chloroplast ATP synthase subunits.  Interacts with the 5'-UTR of the chloroplast bicistronic atpB and atpE mRNA and activates its translation by facilitating ribosome association with the mRNA (PubMed:22708543).  Required for accumulation and activity of the chloroplast ATP synthase.  Enhances atpA translation and is required for accumulation of specific processed atpF and psaJ transcripts (PubMed:22708543, PubMed:23735295).  Required for the stabilization of bicistronic rpl16 and rpl14 mRNAs (PubMed:23735295).
What are the official names of this protein?
Pentatricopeptide repeat-containing protein ATP4, chloroplastic, ATP synthase 4.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PROA_PSEF5
Sequence: MTESVLDYMTRLGRAARQASRVIARATTAQKNRALLAAADALDAARPELTAANEQDLANGRANGLEPALLDRLALTPARIDEMIEGLRQVAKLPDPIGEIRDMRYLPSGIQVGKMRVPLGVIGIIYESRPNVTIDAASLCLKSGNATILRGGSEAIHSNRAIATCIQQGLAAADLPPHVVQVVETTDRAAVGALITMPEFVDVIVPRGGKSLIERVSRDAKVPVIKHLDGVCHVYIDVAADLDKAIRIADNAKTQRYAPCNTMETLLVHSAIAERVLPPLAAIYRDKGVELRGCAQTRALLGAGVLEATEEDWRTEYTAPILSIRVLDNLEQAIEHINTYGSHHTDSIVTENFSDARRFLNEVDSSSVMVNASTRFADGFEYGLGAEIGISTDKLHARGPVGLEGLTSEKYVVFGDGHVRT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD61_CHLRE
Sequence: MGDICETVEATFHGVAYLLTVSTIEGETLCVEVEQKSDCSRWRGDFTSRYIEDITAKTGNFKKFPVFVKMLLSALKQASDSVFVDLLTYQDLEVLKSRKAGGQAPPPRTQPPNNKRYLIMTYAAEFDRVHYPLPLLFEENPDPQHLKRIISQLRSEVEGLQVEAGNRRGGEVSAELRRLREENAALQRQLKQMERSGSGVGAGAESSEARELARELRTVRKERDLLQARVEAAEAELERERGLHRRELRRRAKEQQELVDELGRCKEQIRELKMRIRQLTEDLEARDRRMNSTDRIRSVYARGSNDGSTSGVAPRRPSSGGRGPSSNYMAPTRGADSRSNSRGRGTSSAERSRPNSAPIGGPRPRFDPTEYVRQRKERESAAVGGRRSNAPTPPRSAGTSRASSVVGSRPASAERLPPIRTASPTNSRPSSTERYRPGSGGPPGRTSAGGSRGAADRAGARGPDPYAPRSRGASPSGRATAWGEPGASGGGAGGWSKFPGGGGGGVGGSGQRISSNSPRSMSPARALAEVKQKLSTFVAGRGGSLQGDDASSAHGEHMSQSSKSQVFEDATAEIADIDSRLHALQNFLRMAKTSSTSTSTTQA
What is the function of this protein?
Required for normal flagella and striated fiber formation.
What are the official names of this protein?
Variable flagella 3, Coiled-coil domain-containing protein 61.
What is the protein family that this protein belongs to?
Belongs to the CCDC61 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum basal body. Note=Localizes to basal bodies and the proximal ends of flagella.
Protein: CJ053_DANRE
Sequence: MPTNSIVTIRYGPYDSCGIVDHRTFRLDGLQAVLKGDGHRYVLEKTDDWNTVELIVNGERVYTCNITDLVFGGDGRLDPLCQEAIDAVREAY
What are the official names of this protein?
UPF0728 protein C10orf53 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0728 family.
Protein: TRI23_HUMAN
Sequence: MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQHQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA
What is the function of this protein?
(Microbial infection) Mediates TRAF6 auto-ubiquitination in the presence of human cytomegalovirus protein UL144, resulting in the virally controlled activation of NF-kappa-B stimulation at early times of HCMV infection.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM23, ADP-ribosylation factor domain-containing protein 1, GTP-binding protein ARD-1, RING finger protein 46, RING-type E3 ubiquitin transferase TRIM23, Tripartite motif-containing protein 23.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Cytoplasm. Endomembrane system. Golgi apparatus membrane. Lysosome membrane. Note=Membrane-associated with the Golgi complex and lysosomal structures.
Protein: GPMA_SALA4
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGFSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNDTILPRMKSGERVIIAAHGNSLRALVKYLDNMSEDEILELNIPTGVPLVYEFDENFKPLKHYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PCEP9_ARATH
Sequence: MKLLSITLTSIVISMVFYQTPITTEARSLRKTNDQDHFKAGFTDDFVPTSPGNSPGVGHKKGNVNVEGFQDDFKPTEGRKLLKTNVQDHFKTGSTDDFAPTSPGHSPGVGHKKGNVNVESSEDDFKHKEGRKLQQTNGQNHFKTGSTDDFAPTSPGNSPGIGHKKGHANVKGFKDDFAPTEEIRLQKMNGQDHFKTGSTDDFAPTTPGNSPGMGHKKGDDFKPTTPGHSPGVGHAVKNDEPKA
What is the function of this protein?
Extracellular signaling peptide that represses primary root growth rate and significantly inhibits lateral root formation.  Modulates leaf morphology (PubMed:24179096).  Regulates systemic nitrogen (N)-demand signaling.  Mediates up-regulation of genes involved in N uptake and assimilation pathways (PubMed:25324386).
What are the official names of this protein?
Precursor of CEP9, PCEP9.
What is the protein family that this protein belongs to?
Belongs to the C-terminally encoded plant signaling peptide (CEP) family.
What are the subcellular locations of this protein?
[C-terminally encoded peptide 9.2]: Secreted, extracellular space, apoplast. Note=Accumulates in xylem sap under nitrogen (N)-starved conditions. SUBCELLULAR LOCATION: [C-terminally encoded peptide 9.3]: Secreted, extracellular space, apoplast. Note=Accumulates in xylem sap under nitrogen (N)-starved conditions. SUBCELLULAR LOCATION: [C-terminally encoded peptide 9.4]: Secreted, extracellular space, apoplast. Note=Accumulates in xylem sap under nitrogen (N)-starved conditions. SUBCELLULAR LOCATION: [C-terminally encoded peptide 9.5]: Secreted, extracellular space, apoplast. Note=Accumulates in xylem sap under nitrogen (N)-starved conditions. SUBCELLULAR LOCATION: [C-terminally encoded peptide 9.1]: Secreted, extracellular space, apoplast. Note=Accumulates in xylem sap.
Protein: AROK_BACSU
Sequence: MNAKRAIPVRERNIVLIGFMGVGKTTIGQLVAKKLYRDFIDIDQQIEKDFNMSIPEIFEKKGEDFFRKTEKEYILDICHHKRFKIVSLGGGSFKQEEIRNCCLENCLVLHLDLSWENWKQRADLLIESRPVLHNRSMDEMEQLFNERKVIYDKHNSKVATDNLSPEEVADYIVETLKIGWDLYQPM
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF201_ARATH
Sequence: MRNLINFAVLIMTIFIVSASGARETRMMEQTCPVFWPMVPCDANKCEQMCRDYYGSVPSYCNRIGTPIAECACSLTPC
What are the official names of this protein?
Defensin-like protein 201.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNMG_RALPJ
Sequence: MLYPIEFDVIVVGGGHAGTEAALAAARMGCQTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAIATDEGGIQFRILNSSKGPAVRATRAQADRVLYKAAIRHRLENQPNLMLFQQAVEDLVVEGDRVIGAVTQVGVQFRARAVVLTAGTFLDGKIHVGLNNYTGGRAGDPAAVSLSARLKELKLPQGRLKTGTPPRIDGRSIDFSVLEEQPGDLDPVPVFSFMGRADMHPRQVPCWVTHTNERTHDIIRAGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKDSHQIFLEPEGLATNEFYPNGVSTSLPFDVQLDLIHSMRGLENAHILRPGYAIEYDYFDPRGLKASLESKAISGLFFAGQINGTTGYEEAAAQGLLAGINAGLQVQGKDAWTPRRDQAYLGVLVDDLITRGVTEPYRMFTSRAEFRLSLREDNADMRLTEVGRTLGVVDDARWDAFNRKRDAVSRETERLKSTWVNPATLPLEDAEPVLGKGIEREYALADLLRRPNVTYETLVGMQGGKYALESPLAEDPLLAEQIREQVEIGIKYHGYIARQADEVERLGANENTRLPADFDYSQVRGLSIEVQQKLAKHKPETIGQASRISGITPAAVSLLLVHLKKGVLRGQVGPRASSEGEAA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP6B3_PAPPO
Sequence: MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
What is the function of this protein?
Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
What are the official names of this protein?
Cytochrome P450 6B3, CYP6B3v1/CYP6B3v2, CYPVIB3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: GSA_PSET1
Sequence: MTISQDLFARAQASIPGGVNSPVRAFNGVGGTPLFITKAEGAFTFDADGNRYIDYVGSWGPMIMGHNHPAIKQAVHDAVENGLSYGAPTEAEILMAEKVKELVPSIEKVRMVSSGTEATMSAIRLARGFTGRDKILKFEGCYHGHADSLLVKAGSGALTMGVPNSPGIPEDFAKHTLTVSFNNLDEVKAIFAKYADEIACIIVEPVAGNMNCIPPVPGFLEGLRDVCDEYKSVLIFDEVMTGFRVALGGAQAYYNIKPDLTCLGKVIGGGMPVGAFGGKTEIMDYIAPVGPVYQAGTLSGNPIAMAAGLKSLELLSEPGLHAKLEATSKAICEGFEAGAKKAGIALTTNYAGGMYGFFFTDAEKVTTYKQATECDLERFKRFFHLMLEEGVYLAPSAFEAGFVCAAHNEQEIKDTIAAAERAFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_METS5
Sequence: MAQGKVARVNGPLVVAEGMKDAQMFEVVEVGEPRLVGEITRIEGDRAYIQVYEDTSGIRPGEPVFGSGAPLSVELGPGLLGQLFDGLLRPLGEIKEITKSPFIKRGIKLPTLNREKEWHFVPKMKKGDKVEPGDILGVVQETGLVEHRILVPPYVHGKLKEVVAEGDYKVEDNVAIVDMNGDEVPVKMMQKWPVRVPRPFKEKLDPSQPLLTGVRILDTIFPIAKGGTAAIPGPFGSGKTVTLQSLSKWSEAKIVIFVGCGERGNEMTDELRSFPKLKDPWTGRPLLERTVMVANTSNMPVAAREASIYVGVTLAEYFRDQGYDVLTVADSTSRWAEALRDLGGRMEEMPAEEGFPSYLSSRIAEYYERAGRVRTLGNPERYGSVTLASAVSPPGGDFTEPVTSTTLRFVRVFWPLDVSLAQARHYPAINWLQGFSSYVDLVSDWWIKNVDPDWRIMRDFMVRTLLREDELKQIVRLVGPESLAEKDKLTLEVARLIKEAFLKQNAYDDIDAFSSPQKQARIMKLIYHYNQYATNAVERGIPVKKIVDKITVVPDIIRSKATIKNNELQKYDELENKLKAQFDELLKEAGA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: PURL_THET8
Sequence: MEALAKEIGIPEGEYREIVQRLGREPNRVELLLFKVMWSEHCAYKNSRPLLKALPKEGEAVLQGPGENAGVVRVGEGWAVAFKIESHNHPSAVEPFQGAATGVGGILRDIMSMGARPIALLDSLRFGPPEEARSRYLLKGVVSGIAFYGNAIGVPTVGGDLYFHEGYRENPLVNAMCLGLLREEHLKRSRASLGRPIYYAGAKTGRDGIGGAAFASRELKEEKAEDRPAVQVGDPFLGKLLMEATLEAIELDLVEGVQDMGAAGLTSSLSELAHKSGLGVELHLDLVPTREEGMTPEELLLSESQERMVLVPKEGKEKALEEVFGRWGLDCVPVARTIPERVFRVLFRGEVVAEVPTEALAEAPTYVRVGREDPEVRRLRETPIPPLEADPQEVLRRLLASPNLASREAVYERYDHQVGTRTALLPGKGDAAVLWIKGTRLGVAAKVDQNPRYSRLHPRLGAMHALAEACRNVSVVGAKPLAYTDGLNLGSPETPEGYHELAETIAGLKEASEALGVPVVSGNVSLYNESGGKRIPPTAMVGVVGVLEVDKRAEMGFRRPGEVLLLIGEERGELGASEVLYLLTGKEFGHPPRLDLGREKAVQEAIRDLIQRGLTRTAHDVAEGGLLLALAEMTFPYGVGATVEVREEGLEALFGEAPSRVLFTVEKTRLQEATLLLEERGLPYRVLGETGGKSLTVLTPGGVLEWSLEELLSAWKAPLREVLDG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_BRUME
Sequence: MSASGLPFDDFRELIRNLPGPDLGAERAVREREVTLTKPAGSLGRLEEIVAWLATWTGKRTPQVNRPLVAVFAGNHGVTAKNITPFPPSVTAQMVENFAAGGAAINQICIANDLGLKVFDLALEHPTGDITEEAAMDERTCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAIALALFGGTAEDWVGPGTGSTGELMQRKLAAVRLAVALHQPHLQDPLEVLRCLGGREIAAMAGAILAARMEKIPVIVDGFVASAAAAVLYAANPEAIDHCMFGQVSAEPGHRKLLAKMGKEPLLDLGMRLGEGTGAALAANIVKAAALCHSGMATFEQAGVSASK
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.