PharMolix/UniProtQA huggingface dataset:
Protein: ILVD_ECOLU
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKVCALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: NRM1_SCHPO
Sequence: MDRSMEPLTPSRLNTLGERPTNEVYEYGKGKNVQHLFPITPMQRPLGKENAAPGTISPIAVRSRNVRAVEIADENACEEPVLKIKSVSSTESEEEKESSTEIGEKQEKETHLEPKTPVQTNTNNNHLDDIQCCAKNLRLRLELAMYKVQVNQTFSPLQDLPIVAKTKLHNCPNSEPVTSIWNQRSLSSGKPPSLHLSGNRRLSMGSPTKSIYDQNGLTTPRPIGSDDLTHMYDPYTSPLRTPSRTLSRSSSHYLWVRHGKLTRSVSLLQHKTPRRIRPKSLSKSNSTPLKHLSAQKPNSNYYTGPPTPVSISNTPENIHPSSSEVRRIASHSKQFSDYGLIR
What is the function of this protein?
Negative regulatory component of the MBF complex involved in cell-cycle-dependent transcription.
What are the official names of this protein?
Transcription factor nrm1, Negative regulator of MBF targets 1.
What is the protein family that this protein belongs to?
Belongs to the WHI5/NRM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL9_TRIEI
Sequence: MAKKLQVVLNKDVNKLGKSGDVVDVAPGYARNYLIPNKIAFRTTPGVLKQVERRQEQERQRQIELKQGALAQKTALETVGRFKIAKQVGENDAIFGTVTDRELVEVIKESTGQEIDRRGVTLPEISKIGFYKAEIKLHPEVIAEVEIQVVGH
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SLYX_PSEPW
Sequence: MSPESRIVELETRQAFQDDTIQELNDVVVEQGRVIQRLQLQVAELIKRYEEMVGQYGSEGEEAPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: YYAD_BACSU
Sequence: MLWRAGMKWMLLILGSLIGAGYASGQEIWQFFGAESGLAIVLFTIMFIFSSYIVMKISFKVQSTHFLPVLEHLMGPWLAKIYDVLIIFYLFSTTMVMIAGGGVTLQMYKLPFWWGITLICIVTVCLFLWDVKGILSINSILIPVLVAGLLYALISFQSTHHHTWTIDLSQQYNWPASITFTSLNILSVVAILSSVGKEMKGLGEAKIASVASGLIFGVISFVYNETLVELAGSLSQFEIPLFAVLEGAPYFLFLCMTAVLCLAIYTTTVAGLLGLSSRLMAFIHMPRWMIVLILLVLMVPFTSFGFSDLIAFLYPIYGMLNLYLLVCLLLYPILSKWK
What are the official names of this protein?
Uncharacterized protein YyaD.
Protein: OSB11_HUMAN
Sequence: MQGGEPVSTMKVSESEGKLEGQATAVTPNKNSSCGGGISSSSSSRGGSAKGWQYSDHMENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMSHAEGQQRDLIRRIECLPTSGHLSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTIEWLEPKISLSNHYKNGADQPFATDQSKPVAVPEEQPVAESGLLAREPEEINADDEIEDTCDHKEDDLGAVEEQRSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDRMIRFVEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQGVTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFLGMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVPWVELGGKVSVNCAKTGYSASITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFTYSNGETKYVDLTKLAVTKKRVRPLEKQDPFESRRLWKNVTDSLRESEIDKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLWKIIPTTQPAE
What is the function of this protein?
Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956).  Weakly binds 25-hydroxycholesterol (PubMed:17428193).
What are the official names of this protein?
Oxysterol-binding protein-related protein 11, ORP-11, OSBP-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
What are the subcellular locations of this protein?
Late endosome membrane. Golgi apparatus, trans-Golgi network membrane. Note=Localizes at the Golgi- late endosome interface.
Protein: Y073_VIBC1
Sequence: MIIPWQDIAPETLENLIREFVLREGTDYGSVEVSLQSKIDQVKSQLEKGEAVIVFSELHETVDIQLKAKF
What are the official names of this protein?
UPF0270 protein VIBHAR_00073.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: SECB_CELJU
Sequence: MSDENNQQDAQQAAGGPQFAIQRIYLKDLSFETPMGVEAFTKAFKPNIQQDLNIQANQVEEGLFEVVLLLTVTARTDNRAVFLVEIKQAGLFAIGGLEGGAVTQLINTACPQILFPYAREAIDSILNRGSFPPLMLPPINFDAVFVQAISQAQQQAETEKAQGETIN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMN6_ECOBD
Sequence: MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGVECSTPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_RICPR
Sequence: MYNTNFGFKKVDYTKKQWLINNIFSRVADKYDLMNDLMSIGLHRLWKDEFIMQIPNLNSNILDVASGSGDIALKLAKKAKDRGNNISLILSDINEEMLNNAKKKSIDLNLFQNIKFIVANAEELPFSDNSFDYYTIAFGIRNVPDINKALKEAYRVLKPMGKFVCLEFSKVKEGILKDFYKFYSFNIIPSIGQIIAGNKEAYEYLVESIALFPSQDDFRIMIKESGFEEVHYKNLSGGIVAIHSAYKI
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: MDH_XYLFA
Sequence: MKSLVRVAVTGAAGQIGYSLLFRIAAGEMFGKDRPVILQMLELPDEKAQAALKGVMMELEDCAFPLLAGMVGTDNPDIAFKDADVALLVGSRPRGPGMERKDLLMENAKIFTAQGAALNKVARRDVKVLVVGNPANTNAYIAMKSAPDLNPKHFTAMLRLDHNRALSQLSTKLSKPVANIEKLIVWGNHSPTMYPDYRFATADGTPIIEAINDQAWNANSFIPTVSKRGAAIIEVRGLSSAASAANAAIDHMRDWLLGSNGKWITMGVPSDGSYGIPEGMIFGFPVTTTNGEYSIVKDLPIDTFSKTYIDKTLAELEEERASIAHLLR
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: ARGP_YERPY
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENLFGQPLLVRTVPPRPTEQGQKLLALLHQVELLEEEWLGNDNGVDTPLLLSLAVNADSLATWLLPALKPVLADLPIRLNLQVEDETRTQERLRRGEVVGAVSIQPQPLPSCLVDQLGALDYLFVASKAFAERYFPNGVTRSALLKAPAVAFDHLDDMHQAFLQQNFDLSPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLLQRRMLFWHRFAPESRTMRKVTDALLSYGRQVLRQDSFIGQ
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: HEMH2_SHEON
Sequence: MGHAARGKVGVLLLNLGTPDAPTASAVRRYLAEFLSDPRVVEIPKLLWMLILYGIVLRVRPAKSAALYQKVWTEAGSPLMDISLRQTAKLSDKLTADGHQVSVHLAMRYGNPSVASTLREMHKQGIDKLVVLPLYPQYAAPTTGSAFDAIAKELSQWRYLPSLHFINTYHDNPDFIAALVNSIRDDFDKHGKPQKLVLSYHGMPERNLHLGDPYYCFCMKTTRLVAEQLGLSKDEFAITFQSRFGKAKWLQPYTDATMAALPSQGVRDVAIVCPAFSADCLETLEEIVGENGHIFTHAGGEKFRYIPALNDNDDHIAMMANLVKPYL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase 2, Heme synthase 2, Protoheme ferro-lyase 2.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_WOLPM
Sequence: MECNLVNLSNDNVGAAQLNPLIFSAKQKLSILHDIVRWQLAKRRAGTHKTKGISDVSGTTAKPYGQKRTGRARQGSLRSPQFRGGGIIFGPVVRSHTYSLNKKVRKFGLKIALSLKYLNNQVIILDNLNIDVKKTSEMCKCIKNFKFSSFLIVGDYGDDLLRAAKNLHYVDLIKPIGLNVFDILNHECVMLTKDTLKHLEGRLL
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CLUL1_RAT
Sequence: MQPPLFVISVYLLWLKYCDSAPTWKETDATDGNLKSLPEVGEADVEGEVKKALIGIKQMKIMMERREEEHAKLMKALKKCKEEKQEAQKLMNEVQERLEEEEKLCQASSIGSWDGCRPCLESNCIRFYTACQPGWSSVKSMMKQFLKKIYRFLSSQSEDVKDPPAIEQLTKEDLQVVHIENLFSQLAVDAKSLFNMSFYIFKQMQQEFDQAFQLYFMSDVDLMEPYPPALSKEITKKEELGQRWGIPNVFQLFHNFSLSVYGRVQQIIMKTLNAIEDSWEPHKELDQRGMTSEMLPEQNGEMCEEFVKNLSGCLKFRKRCQKCHNYLSEECPDVPELHIEFLEALKLVNVSNQQYDQIVQMTQYHLEDTIYLMEKMQEQFGWVSQLASHNPVTEDIFNSTKAVPKIHGGDSSKQDEIMVDSSSILPSSNFTVQNPPEEGAESSNVIYYMAAKVLQHLKGCFETW
What are the official names of this protein?
Clusterin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the clusterin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CBPA_COXBR
Sequence: MEYQDYYKILGVSRDATADEIKKSYRKLARKYHPDVSSEPNAEEKFKQVKEAYEVLKDVEKRKAYDAIGSGWKQGQGFTPPPGWESRPGGEGVRPEFREGFSDFFESLFGGLGQEARWTRQEFKQRGQDQHSRVTVSLEEAFNGSTRLLTLQEPIVDYQTGQVTSKTRQLRIKIPAGVTEGQQIRLQGQGLPGIGGAPNGDLYLEIHLAPHSLFTVEGKDVYLNLPVTPWEAALGAKVSIPTLGGSVDLTLPPGSQTGQKLRLKGRGLPGGTPGDQYVLIKIYIPEPKNDQQKELYQQMAEQMPFDPRKELLG
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RECX_MYCLB
Sequence: MTTSCPPPSISDREEQARILCLRLLTARSRTRAQLFGQLAKRGYADHVSERVLDRLAAVGLLDDNDFAEQWVRSRRANVGKSKRALAADLRAKGIDSEVITTVLAGIDPAVERERAEQLVRTRLRREVLSEDDARVSRRLMAMLARRGYSQTTICEVVVAELAAERERRRV
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CY550_RIPO1
Sequence: MKRFILLAIATVFFFCQFQTNPVNALELDEATRTVALDETGKTTIVTSKQITNGQRLFVQECTQCHLQGKTKTNNNVSLGLDDLAGAEPPRNNVLALVDYLKHPTSYDGEDNYEELHVNVTRPDLFPELRNFTEDDLYDVAGYVLVAPKLDAYWGGSIYF
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550, Low-potential cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: DPOD4_MOUSE
Sequence: MGRKRFITDSYPVVKKREGPPGHSKGELAPELGEDTQSLSQEETELELLRQFDLAWQYGPCTGITRLQRWSRAEQMGLKPPLEVYQVLKAHPEDPHFQCSLWHLYPL
What is the function of this protein?
As a component of the tetrameric DNA polymerase delta complex (Pol-delta4), plays a role in high fidelity genome replication and repair.  Within this complex, increases the rate of DNA synthesis and decreases fidelity by regulating POLD1 polymerase and proofreading 3' to 5' exonuclease activity.  Pol-delta4 participates in Okazaki fragment processing, through both the short flap pathway, as well as a nick translation system.  Under conditions of DNA replication stress, required for the repair of broken replication forks through break-induced replication (BIR), a mechanism that may induce segmental genomic duplications of up to 200 kb.  Involved in Pol-delta4 translesion synthesis (TLS) of templates carrying O6-methylguanine or abasic sites.  Its degradation in response to DNA damage is required for the inhibition of fork progression and cell survival.
What are the official names of this protein?
DNA polymerase delta subunit 4, DNA polymerase delta subunit p12.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase delta subunit 4 family.
What are the subcellular locations of this protein?
Nucleus. Note=Partially recruited to DNA damage sites within 2 hours following UV irradiation, before degradation.
Protein: RS20_LEGPH
Sequence: MANIKSAIKRARQNVKLRQHNASARSMYRTYIKNVLKAVESGDQEAARAAYTKAQPVIDKAANKGLIHKNKAARIKGRLVARLKAMAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: Y4MK_SINFN
Sequence: MTDASKDIVSVRSLTKSYGATVVLKGVDFSVARGEIHALLGGNGAGKSTLIRVITGTAAKDGGELVFRDMAGNILTEADGRRKVAVVHQELALLPHLTVAESIALPHFRKGSRVYDGRTAGSQAYAALSMIDRDFAGTALNRLVGDLSLHEGQMVEIARALSSGAELILLDEPTANLTAAETERLFGVLRKLTRGNGLSVVFVSHRMKEIRQIAHVCSIIRDGRTVVGNVPTAELSDLAIIEHMGQAQATAVAHSARPAPVASLSDEPLTIAETGFSVTLQPGTILGVAGAPAGPETLIAALIGAAHERRWTVTRAGWPDRFRSPREAARLGAGFVTGDRSHRGILHSLPIIDNVLASRRATRGSLFATKREEVECLDLMQALKVKAGSLWHLPNTLSGGTQQKLLLARWLNVPSRLLVLEEPTRGVDIGTKREIYQLIRDMATTGTAIVWWSTENAELLEICDQVLAFDTEGRSSGVIERDELSEDKLATLTGMAA
What is the function of this protein?
Probably part of the binding-protein-dependent transport system y4mIJK.  This system probably transports a sugar.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein y4mK.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYH_SULTO
Sequence: MISYEPVRGMKDYYGEELHKIKVVENAFLKIVKLAGYQEVETPIVEDFQLFALKGGEELRNTMYVFKDKAGREVALRPEFTPSIVRFYLNSLQHLPKPIRLYYLGTVYRYDEPQFGRYREFRQAGIELLGSSNIYSDLEILQILIEIYRELNLINKIRLKINNISLIRKILNKLNISDNLQEHFLHLIDKGKIDEALSLLPSSEYTELITNILSVNNLDISSYNKIKEDLTEKYNLKDLIQDLDRIMLLKNILDNLGVNSYIDLGFVRGLAYYTGLIFEVLHPSVSFSIAGGGRYDNLVELYGGPQTPAIGFAIGVERTALVLEEPNTVKEKQNKIGVIVLSDEAILYAIRIVDKLRSNNYIATINLKSISISKLIPSYAEEGYSFLIFIGKKEYEDKTITLKNLSTKEQVTIKEENLLDYLKQII
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B1H2_LOXIN
Sequence: MLLCAVISFIVYAVFLQEANGHAAERADSRKPIWDIAHMVNDLELVDEYLGDGANGLELDVAFTDDGTADKMYHGVPCDCFRSCKRTEGFTKYMDYIRQLTTPGNSKFKSQLILLIMDLKLNGIEPNVAYAAGKSVAEKLLSGYWQNGKSGARAYIVLSLETITRPDFISGFRDAIKASGHEELFEKIGWDFSGNEDLGEIRRVYQKYGIEDHIWQGDGITNCLPRGDYRLTEAMKKKNDPNYKYTLKVYTWSIDKESSIRNALRLGVDAVMTNYPARVKSILRESEFSGTHRMATYDDNPWQK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) with low activity (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LiSicTox-betaIA1ii, Dermonecrotic toxin-like II, Loxtox i7, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 7, SMD 7, Smase D 7, Sphingomyelinase D 7.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SPD14_HUMAN
Sequence: MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS
What are the official names of this protein?
Putative speedy protein E14.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
Protein: MATK_TRIWI
Sequence: MKEYRVYLERARSRQQDFLYPLIFREYIYGLAYSHNFNRSIFVENGGYDNKYTLLNVKRLITRMYQQNHLIISANDSNKNPFLGYNKNFYSQIISEGFAIVVEIPFFLQLSSSLEEAEIIKSYKNVRSIHSVFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDVPFFHLLRWFLYHFXNWNCFIPTKKSISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSYHLRLKSFSVFFERNFFYAKREHLVEVFSKDFSYTLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWKYYFIHLWQCFFDVWSQPRTININQLSEHSFQLLGYFSNVRLNRSVVRSQMLQNTFLIEIVSKKLDIIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIXRFLRICRNLSHYYNGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSFTLHRFHRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TSKS_HUMAN
Sequence: MASVVVKTIWQSKEIHEAGDTPTGVESCSQLVPEAPRRVTSRAKGIPKKKKAVSFHGVEPQMSHQPMHWCLNLKRSSACTNVSLLNLAAMEPTDSTGTDSTVEDLSGQLTLAGPPASPTLPWDPDDADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLLTDKMKPEEKMATLDHLHLKMCSLHDHLSNLPLEGSTGTMGGGSSAGTPPKQGGSAPEQ
What is the function of this protein?
May play a role in testicular physiology, most probably in the process of spermatogenesis or spermatid development.
What are the official names of this protein?
Testis-specific serine kinase substrate, Testis-specific kinase substrate, STK22 substrate 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Concentrates in spermatid centrioles during flagellogenesis.
Protein: POF13_SCHPO
Sequence: MRPTHWSSNQCEVDFTAEALTTLSLSNRNHEEDPIQPVLKNSNLFLLNRDIWSLIINYLDAFDILRLMHSSRQFYYWLRKSAVDECCFNNNFLNLQPYQRTVPVASDLEWATEVDLYGNPPILKLQLRDSFVWSMLAKFQGLQTIALDGTGVTISSVTNILLNIPTVKTLSIRWCVGVCSLSLIEFLQNSKSRTFSLENLYVLGVKGLELLKPVLLDGSEDDTLTSNWHSRVILFQNALDALPTTHGNPVECDISRCPLNACKIAGQETELADLFSLQKVPACIYCLREWKKPICRYCIDLRSCLVCDSFVCPSCISLDFDLQIQAFARQHRVISTLGVVYPEREDSCFHKIKAAQWHQISPRSLLFQFQEQNHIHHKKIRRKLLAAGWKWPQSQI
What are the official names of this protein?
F-box protein pof13.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y705_BIFLO
Sequence: MNQQTTNRDTGEAAATNAPANSATSTSTPDNQPTPLDAFEVLLITGMSGAGRSHAADCVEDMGWYVVDNLPPKLLIPLVDMMTTSGSGSESGVHKLAAVIDVRSSYFDELAAVLGHLDDLGVKTRILFLDASNEVLIKRYESVRRPHPLQHGNRLIDGILEERHLLEDLKERADWVIDTSSLSIHQLSTKLYEAMLGSGPTTVAVHIFSFGFKYGMPIDADFVADVRFLPNPFWVPSLRELTGRDKPVADYVLSSKGAKEFLDAYEKAIEIALEGYAQEDKHYVTIAVGCTGGQHRSVAMSEELARRLRAHGLNVTVSAREQHKRHSS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BL0705.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: FH16_ARATH
Sequence: MSPVEITGADAVVTPPMRGRVPLPPPPPPPMRRSAPSPPPMSGRVPPPPPPPPMFDPKGAGRVICCLRPGQNKSSLKRFQCGKLTNAWEELQRHGEAQTAPEFDLSEIEALFSAAVQNQADKSGSRREAFEANPDKLQLISGADALVPLPPPPPPMPRRSPPPPPPRFDAFDHKGARMVCGFRCPVTKRSSLKPLHWVKITRALQGSLWDELQIQYGESQTAIELDVPEIETLFSVGAKPRPKPKPEKVPLIDLKRANNTIVNLKILKMPLPDMMAAVMAMDESVLDVDQIENLIQLCPTKEEMELLKNYTGDKATLGKSEQCLLELMKVPRFEAKLRVLSFKIPFGTKITKFRKMLNVVNSACEEVRSSQMLKEIMKIILFLGNTLNQGTARGSAVGFRLDSLLILSETRADNNKMTLMHYLCKVLASKAADLLDFHKDLQSLESTLEINLKSLAEEIHAITKGLEKLKQELTASETDGPVSQVFRKLLKDFISSAETQVATVSTLYSSARINADALAHYFGEDPNHYPFEKVSATLLSFIRLFKKAHQENVKQEDLEKKKAATEDVFGGPDHNIDSDTSLDDSEAKSPSRIRPPPSIPRPPSRPRYACCRIPAVNPPPRLVCGPYPLPRLVRVGSPSPPPPSMSGGAPPPPPPPPMLVASRTAPPPHLSHVRSIPFQTRLVMGTSPLPLLVREGAPPPTLPSMSGGAPPPPPPLPMLRYQ
What are the official names of this protein?
Formin-like protein 16, AtFH16.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-II subfamily.
Protein: NDK_DESHY
Sequence: MEKTFIMLKPDAVQRGLVGQIIARFETKGCKLVGMKLMSVDQALAEQHYAEHKGKSFFEPTVQYIMSSPVVAMVWEGKNVVALARELMGATNPANANPGSIRGSFGMDISRNVIHGSDSVASAEREIALYFRPEELCDYRKAGEEWLSE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_LEIXX
Sequence: MTEPATPPVVLAVDGPAGSGKSSVSKAAAGRLGWAYLDTGAAYRALGWYVVERGLDPADPAVVIDSLPDFDYRIGTDPDTYRVFVGERDVTEAIREPRVTAVVSAIARVPQVRASLTRLFREIIAGSGKAGIVVEGRDITTVVCPDALVRILLTADEAVRMNRRSAELTGHSAARVGEALRKRDAADSRVVDFMNAAEGVITVDSTELDFDQTVDAVIAVVQKETHV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7931_DICDI
Sequence: MGLKIVDGSIVHDNLTSSSPPSVTNSSPLLNTKRRNSITSLSDYKKNKDTLNNSNNNINQPFENSNNFNNNSKEIKNENKIKNFFQHLFSILLLKNPTMIQIIETLELSTNIYNIQFKLKYLLAICVSSQIIFKSSGLLITLLVLYLGTFFNKISINNKDKNKNNNTIDYSLKNNNIDTSLIKDINNSVISNNSSNSNNNNINNSNNNNNNNNRILSPNQLSKSSNVEYNKCKCKSPTTSSNNYLSSSQSRVQTLSSPNISPCNICVSPNLLYNSLSSLSSSLPINSCNYSMSEQEGDEFESNFDFEDSQYEESDEEDNSSPAFHLYSSPNLRVACNKISTFSPNGRKLGTN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0274369.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.