PharMolix/UniProtQA huggingface dataset:
Protein: AROC_MYCLB
Sequence: MLRWITAGESHGRALVAVVEGMVAGVEVTSTAIADQLARRRLGYGRGARMAFERDGVTVLSGVRHGVTLGGPIAIEIDNTEWPKWESVMAADPVDAAELEDSARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTIARQFLRQALGVEVLSHVISIGASARYDGPPPGSEDLTVIDASLVRAFDEQVEKSMIAEIEAAKKDGDTLGGVVEAVVLGLPVGLGSFTSGDDRLDSQLAAAVMGIQAIKGVEIGDGFATARRRGSCAHDEMYSGPGGVVRLTNRSGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDLATGEEAIAIHQRSDVCAVPAAGVVVETMVALVLARAALRKFGGDSLGETRRNLAAYQRAVADREAPVAQYCGESGIGG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PKHG7_HUMAN
Sequence: MEKTESFCPEVPPQDCGASPRPSLRSLPKNQGSLLQFDRQAPGRISTSPTLRRLRTRGCGTRQDAWQVTTWGSWGAPVGFPCYLSKSLPGSPKDSSHLLSPLRLHSRLTSEPERALNAADSLEPQTRPTDKYLPPELQPVNEGSLHQASLRQQEGHFLPSPTLRHPSPQGEELHPSRFYEHRRSSVVLNLPGLEVFPGDLLVSDGAADYLCHPLLLLNSESKKPRWPFSKRGVGKDKHKHISDLENCLSSVKITSFRGYDFYGLKDKTWDEVLETHHKLPTDQLDLKKQQEAVWELFTSECTYFLDHLLVLKMIFMNTLRYLQTHEYLLDVDLWRLFANLEELTQTSLGFVNSLFGIIKDYVDASEISSSLDFISVLTKYFRGSLCQSHQTYCLNYSAAIFYLESLRQRDDFGIYLKWCEQNEQCRRLHVPELLVAPLQRLTRYPLLLKNIWKRSMDSAEKIMIYSIKEKVEKSIRDLEGKVKWLDNFQKFRYLQEIIVWPPLWDRDKRFFIPECLKHIFKEHMAENILSPTSRHLLYEGKLTLAESTRFLDVYLFLFNDFLLVTKTKCNKKKLGGSDPGLMCPSLTPELQAVIKEGGSCTVLDQPIPLDRLVVKSIEPLHVSVFGLRNAFLIQHENRYRQCIAAFLLQAQTENIKKTWMAQITTAISCFTKSQETKKISLFTLPAESSEI
What are the official names of this protein?
Pleckstrin homology domain-containing family G member 7, PH domain-containing family G member 7.
Protein: MNTC_LISIN
Sequence: MLFLEGLMQYGFLQKALITSVTVGIVSGVIGSFIILRGMSLMGDAISHAVLPGVAISYMMGMNFFIGAATFGIAAALGIGFVNQKSRIKNDTAIGIVFSAFFALGIILISFAKSSTDLYHILFGNVLAVRSSDMWMTIIIAILVISLVAIFYKEFLVSSFDPVMAEAYGLNVRFLHYFLMLLLTLVTVSALQTVGIILVVAMLITPAATAYLLTNKLSKMIMLASTFGAVSAIIGLYFSYIFNLASGAAMVLVATIIFFIAFLFAPKQGLLFSKKKEVIE
What is the function of this protein?
This protein is probably a component of a manganese permease, a binding protein-dependent, ATP-driven transport system.
What are the official names of this protein?
Manganese transport system membrane protein MntC.
What is the protein family that this protein belongs to?
Belongs to the ABC-3 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM3_GLOVI
Sequence: MSRTVIIGSRDSQLALVQTHWVRDELQRAHPDIRFEIVEMKTQGDKILDVALAKIGDKGLFTKELESAMLEKRTDLAVHSLKDLPTALPPGLILGAITEREDPSDAVIVRRGLEAAGLADLPEGAVVGTSSLRRLAQLKHHYGERLRFQDIRGNLNTRLRKLDEGRYDAIVLAVAGMRRLGWSERISEVLSPDISLHAVGQGALGIECREADGEILDLLTVLNHPPTARRCRAERAMLRALEGGCQVPIGVYTELDDSGRLTLQGIVASLDGRNMARACRSGPGDAPEALGRAVAEDLKAAGAQAILDQIFVLVRSPGVIAPGAAPAS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: GSA2_OCEIH
Sequence: MTLNQSIDAYKEAVDLMPGGVNSPVRAFKSVGMNPIFMKEGKGSKIVDIDNNEYIDYVLSWGPLILGHSDERVVKKLQDITAKGTSFGAPTLLENDLAKLVIDRVPSIEMVRMVNSGTEATMSAIRLARGYTDRDLILKFEGSYHGHGDSLLIKAGSGVATLGLPDSPGVPENIAKNTITVPYNDTDSLKLAFENYGDRIAAIIMEPVCGNMGVVPPKDGFLQYVRHITEENGSLLIFDEVMTGFRVGYHCAQGHYDVTPDLTCLGKVIGGGLPVGAYGGKREIMEQIAPTGPIYQAGTLSGNPLAMTAGYETLSSLSEESYEDINNKVDTLVNGFRDAADKFDIPIHINRAGSMVGVFFTDEEVINFETAQTSNLDYFAQYYRSMVNEGIFLPPSQFEGLFLSTAHTDDDIEKTVKAIHKAFEQIEK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETM_THEVB
Sequence: MAEEIFNTAVITFTLVLVGLGAGYLLLRLTPDD
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 7, Cytochrome b6-f complex subunit PetM, Cytochrome b6-f complex subunit VII.
What is the protein family that this protein belongs to?
Belongs to the PetM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MATRX_RABVC
Sequence: MNVLRKIVKKCRDEDTQKPSPVSAPPYDDDLWLPPPEYVPLKELTSKKNMRNFCVNGEVKACSPNGYSFRILRHILGSFNEIYSGNHRMIGLVKVVVGLALSGAPVPEGMNWVYKLRRTLIFQWADSRGPLEGEELEYSQEITWDDDTEFVGLQIRVGARQCHIQGRIWCINSNSRACQLWSDMSLQTQRSEEDKDSSLLLE
What is the function of this protein?
Plays a major role in assembly, budding and uncoating of virion after membrane fusion.  Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form.  Inhibits viral transcription and stimulates replication.  Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons.
What are the official names of this protein?
Matrix protein, Phosphoprotein M2.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus matrix protein family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein. Host cytoplasm.
Protein: G1PDH_PYRCJ
Sequence: MKKVERFEVPRTIIFGPGALEKTPEVIPPSGRVLIITGKSSTRKYAERVAELLKQNCEIISYDQVELEKPGFDLVIGIGGGRPLDMAKVYSYIHKKPFVAIPTSASHDGIASPYVSFSLTQRFSKYGKISSSPVAIIADTSIILSAPSRLLKAGIGDLLGKIIAVRDWQLAHRLKGEEYSEYAAHLSLTSYKIAVGNAQKIKNFIREEDVRVLVKALIGCGVAMGIAGSSRPCSGSEHLFAHAIEVRVEKEDEVVHGELVALGTIIMAYLHGINWRRIKRIADIIGLPTSLRQANIDVDLALEALTTAHTLRPDRYTILGDGLSREAAKRALEDVELI
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_MICLC
Sequence: MPASTLNDLLEAGVTGRTVLIRSDLNVPLDGDTVTDDGRIRASLPAIRDLAEAGARVIVMAHLGRPKGEPDPAYSLRPVAARMAELLGADVALAADVTGDDARAQAAALQDGQVLLLENVRFDARETSKDDAERAALAGEMAALAGEDGAYVGDAFGAVHRKHASVFDVAAQLPAYQGPLVAAELEVLTRLTESPEQPYVVVLGGSKVSDKLAVIDNLLDKADTLLIGGGMLFTFLKAQGHEVGASLLEEDQLDTVRAYLRRSEAGAARIVLPTDIVMASGFAADAEHEVLAADALTSGAHGASAMGLDIGPETARAFAEQIRGAQTVFWNGPMGVFEFPAFAEGTRAVARALTEASAAGGLSVVGGGDSAAAVRTLGFADDAFGHISTGGGASLEYLEGKELPGVTALAGEGRA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_CHLL3
Sequence: MVWFKRVKPFIRTTDRRDVPEGLWSKCEDCGAMLHRRQLEENLNTCNECGHHFRISPYRYFSILFDNEEFTEFDDCLRAADPLTFVDTKKYPDRVHDTIEKSGKTEACRNAFGKSAGADLVISAMDFGFIGGSMGSVVGEKISRAADKAIELNAPLIVISQSGGARMMEGAFSLMQMAKTAARLTRLGENRLPFISLMTDPTMGGISASFAMLGDLNISEPKALIGFAGPRVIRDTIKRDLPEGFQRAEFLQEHGFVDMIVHRKELKQRLAKTLAMMRVEG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOD1_MESAU
Sequence: MDFKRRQGPGPGVPPKRARGGLWDEDEPSQFEENLALLEEIEAENRLQEAEEELQLPPQGPAGGQFSTADIDPRWKRPALCALDPNTEPLIFQQLEIDHYVGSAVPLPGGPPTSCNSVPILRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFGAEHLSDLQRELSTAISRDQRGGKELSGPAVLAIELCSRESMFGYHGHGPSPFLRITLALPRLVAPARRLLEQGIRVPGLGTPSFAPYEANVDFEIRFMVDADIVGCNWLELPAGKYVWRTEKKATQCQLEVDVLWSDVISHPPEGQWQRIAPLRVLSFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLRLALTLRPCAPILGAKVQSYEREEDLLQAWPNFILAMDPDVITGYNIQNFDLPYLISRAQTLKVDRFPFLGRVTGLRSNIRDSSFQSRQVGRRDSKVVSMVGRVQMDMLQVLLREHKLRSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNEQTRRRLAVYCLRDAFLPLRLLERLMVLVNNVEMARVTGVPLGYLLSRGQQVKVVSQLLRQAMRQGLLMPVVKTEGGEDYTGATVIEPLKGYYDVPIATLDFSSLYPSIMMAHNLCYTTLLRPGAAQKLGLKPDEFIKTPTGDEFVKSSVRKGLLPQILENLLSARKRAKAELAQETDPLRRQVLDGRQLALKVSANSVYGFTGAEVGKLPCLEISQSVTGFGRQMIEKTKQLVESKYTLENGYNANAKVVYGDTDSVMCRFGVSSVAEAMSLGREAANWVSSHFPSPIRLEFEKVYFPYLLISKKRYAGLLFSSQPDTHDRMDCKGLEAVRRDNCPLVANLVTSSLRRILVDRDPDGAVAHAKDVISDLLCNRIDISQLVITKELTRAAADYAGKQAHVELAERMRKRDPGSAPSLGDRVPYVIIGAAKGVAAYMKSEDPLFVLEHSLPIDTQYYLGQQLAKPLLRIFEPILGEGRAESVLLRGDHTRCKTVLTSKVGGLLAFTKRRNCCIGCRSVINHQGAVCEFCQPRESELYQKEVSHLNALEERFSRLWTQCQRCQGSLHEDVICTSRDCPIFYMRKKVRKDLEDQERLLQRFGPPGPEAW
What is the function of this protein?
As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair.  Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities.  Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity.  Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol-delta4), displays differences in catalytic activity.  Most notably, expresses higher proofreading activity in the context of Pol-delta3 compared with that of Pol-delta4.  Although both Pol-delta3 and Pol-delta4 process Okazaki fragments in vitro, Pol-delta3 may be better suited to fulfill this task, exhibiting near-absence of strand displacement activity compared to Pol-delta4 and stalling on encounter with the 5'-blocking oligonucleotides.  Pol-delta3 idling process may avoid the formation of a gap, while maintaining a nick that can be readily ligated.  Along with DNA polymerase kappa, DNA polymerase delta carries out approximately half of nucleotide excision repair (NER) synthesis following UV irradiation.  Under conditions of DNA replication stress, in the presence of POLD3 and POLD4, may catalyze the repair of broken replication forks through break-induced replication (BIR).  Involved in the translesion synthesis (TLS) of templates carrying O6-methylguanine, 8oxoG or abasic sites.
What are the official names of this protein?
DNA polymerase delta catalytic subunit, 3'-5' exodeoxyribonuclease.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with PCNA and POLD3 at S phase replication sites. After UV irradiation, recruited to DNA damage sites within 2 hours, independently on the cell cycle phase, nor on PCNA ubiquitination. This recruitment requires POLD3, PCNA and RFC1-replication factor C complex.
Protein: SUCC_SULNB
Sequence: MNVHEYQAKQIFAEYGVPTPKGIMAESVDAAVEAAKELGGPIWVVKAQIHAGGRGLGGGVKLAKSLDEVRELADEILGMTLVTHQTGPEGKLVQKLYIEDGADIKDEFYLSVILDRKLEMPLIMASTEGGMNIEDVAENTPEKIITVPVDPTIGFQGFHGRELAFGLGITDKAEQKNIITFAQKLYKLYMDKDAEMIEINPLVRTGSGEFLALDGKMGFDNSALYRQPEIAAMRDLSEEDPDEVEAAKYGLSYVALDGEIGCMVNGAGLAMGTMDTINHMGGTPANFLDVGGSANAETVAKGFEIILKNPNVKAIFVNIFGGIVRCDRIANGIIEATKITDVHVPVIVRLDGTNAPEAAEILKNANISNLIVAEDLGDGAAKAVAAAKGEI
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MNMA_LISIN
Sequence: MSTNNSDIRVVVGMSGGVDSSVTAHILKEQGYDVIGIFMKNWDDTDEFGVCTATEDYDDVIRVANQIGIPYYAVNFEKEYWDKVFTYFLDEYKLGRTPNPDVMCNKEIKFKAFLEHAESLGADYVATGHYAQVKKVGDEIELLRGVDNNKDQTYFLNQLSQDQLKKVMFPLGGMEKTEVREIATKAGLATANKKDSTGICFIGERNFKQFLSEYLPAQPGDMRTLNGEVLGKHDGLMYYTIGQRHGLGIGGDGEPWFVVGKDLKNNVLFVEQGFHHDSLYSDSLIATDISFTTNSEKPKTFVCTAKFRYRQTDTKVTVNMREDGTAEVVFADPVRAITPGQAVVFYDGDICLGGGTIDTVWKKGAKLNYVG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUF1_LEIIN
Sequence: MKLCGVRSSGVSLTRSSDFPRFRAAHHGGAHTATRHQSLCGRRLDSYMGAGKRWCFRPLLAEPRRYSNASSAFTTDGATAPAHGEGLYVSHYAMPEDARRLVGTPQLLPRNPAEEVAFKKNLIRSFPQACIRNVSVVAHVDHGKTTLSDAMLRFSNLLPADGATGTFTDRLKVEKERGITIKAQTCSVLLTLRETGTQYLVNLIDTPGHVDFQYEVSRSLCASEGAALLVDVRQGVEAQTMAQFYAALEQNLTILPVLTKMDSVMSDAEVEKTLLQLEDSTGLLSREVILTSAKSKRGIEQLFQHIIDKVPPPCGREGFSDMKQLPAMHPGSADRKKVEKELVPLRALLFDCWTSESSGMADGAASAPVSTASSVSSGTAPASGGQSVAKDGIYGLIRVMDGTVTPGTTVTFFHSGKKHEVREVGIIHPTLHPTAALTAGMVGFVFFPGLLKKDVFIGDTLCTLPTRKHTMRVVATGSPATASRTKPATAAETASSDDASGSGSSSVVEPIPGFKTVQPVVFAGFYPDEGVYITQLREAVDLLCVNDPSVTVEQLQCPALGPGLQLGFLGFLHMQVFKERLLMEFGQAVLVTPPQVQYMYVEQHGDPDDPAQRKPVSVSNWRWPHEGVGAYLEPFVTATVLTPSEYLNEINSAALSAFRGEMQEMRVIDGARTLVRYRMPLADLARGFFSTVKSSSHGYATLEYDDLTYMTADLVKMDIVINKAHISALSTICLRHEANTHARRIIGSLKEKLLRSSVDLPLQALVGSKIIARETVKAYRKDVTAKIHAGDISRKQKKWNDQKKGKERMARRSVGTVTLDQSVLAAALGATTAR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PSPB_PIG
Sequence: FPIPLPFCWLCRTLIKRIQAVVPKGVLLKAVAQVCHVVPLPVGGICQCLAERYIVICLNMLLDRTLPQLVCGLVLRCSS
What is the function of this protein?
Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.  SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
What are the official names of this protein?
Pulmonary surfactant-associated protein B, SP-B, 8 kDa protein, Pulmonary surfactant-associated proteolipid SPL(Phe).
What are the subcellular locations of this protein?
Secreted, extracellular space, surface film.
Protein: RS18_RUBXD
Sequence: MAKKKGGATTRSGKKKVCVFCKENIEYVDYKDYNMLRRFTSERGKIRARRVTGLCPQHQRETARAIKRAREMALLPYIAGR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RS21_STRZJ
Sequence: MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVKRKRKSEVARKRKKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CD209_GORGO
Sequence: MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAALLVQVSKVPSSISQEQSRQDAIYQNLTQFKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKQQEIYQELSQLKAAVGELPEKSKQQEIYQELSQLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELSQLKAAVGELPEKSKQQEIYQELSQLKAAVGELPEKSKQQEIYQELTQLKAAVGELPEKSKQQEIYQELTQLKAAVERLCRRCPWEWTFFQGNCYFMSNSQRNWHDSITACQEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNHEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPASATPNPPPE
What is the function of this protein?
On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates.  May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2.  Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells (By similarity).
What are the official names of this protein?
CD209 antigen, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN1.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: BTUC_SALA4
Sequence: MLTFARQQQRRNVRWLLSLSLLVLLATLLSLCAGEQWIAPGDWLSARGELFVWQIRLPRTLAVLLVGAALALSGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPGWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSFDLRQLMYWMMGGFGGVDWQQSWLMIALIPVLIWICCQSQPLNMLALGETSARQLGLPLWFWRNLLVVATGWMVGVSVAMAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGAIALLLADVVARLALASAELPIGVVTATLGAPVFIWLLLKSAR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NSAPB_XENLA
Sequence: MDAPTLSELEGLRYSELQKLAKTAGLKANLKADKLLKALKVHFYPESKDESPDSDGCTSLTDTDELNSSQEKEEPVSVSFVTHRRGRGRKPLQNQAIPKDEFLSDSAGVGSESLASEIDNTQDKDCLESKKKEVSLPILDNKHKKRSRSQDTSKQNNSETTEKRQKKASNVSSIPSAGKIPRYVGRLSKPGSKPSTPNFKKLHEAHFKKMESIDKFMERKQKRLDAVSSSIQEVKMLTKKSNLLKLVEKTPVSDIKKPVKSRLSLLSPLPRTTGASPSRTPMSRRRSGRFSTANKSILVDRSGFKPSVLSSSKMNVRFSEATKDNEYKRSLIKTPARKSSSFLPITPKSEPRQTLSSIKKTDLLTSPEKAKKPDHNTTIQPSPAITESPCQQNKANTPFKFMAQNTETPNTNKKGSFDLQASLSRPLGYQPHRGKLKPWGESKENKSGSNSNVSVLKNNFKQPQLQTREERRKQHELDRKGKRDQALGTRRGVPVK
What is the function of this protein?
Microtubule-associated protein with the capacity to bundle and stabilize microtubules.  May associate with chromosomes and promote the organization of meiotic or mitotic spindle microtubules around them (By similarity).
What are the official names of this protein?
Nucleolar and spindle-associated protein 1-B, NuSAP B.
What is the protein family that this protein belongs to?
Belongs to the NUSAP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Associates with meiotic or mitotic spindle microtubules, particularly in the vicinity of chromosomes.
Protein: SPLB_STAAM
Sequence: MNKNVVIKSLATLTILTSVTGIGTTLVEEVQQTAKAENNVTKIQDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
What is the function of this protein?
Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln.
What are the official names of this protein?
Serine protease SplB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS19_MANSM
Sequence: MPRSLKKGPFLDLHLLKKVEKAVESGDKKPIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSDEMIGHKLGEFAPTRTYRGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MNMA_ANAPZ
Sequence: MINNLQLDSLVPGKRPEETTVVVAMSGGVDSSVVAVLLHKMGYKVIGATMQLYSSPNASSGKSCCGNADIYDAKKVAASFGFPHYVLNYEEVFRKEVIEDFVNSYKAGETPIPCIKCNQTVKFRDMLKMARTIGGDVVATGHYVRRLEVEGELQIWSGKDKNKDQSYFLFSMTLEQLKFVRFPLGNLVKGDVRKIAQYLNIEVADKPDSQDICFVPKNYKKTLASLDPSAIKKGKIHHIDGSVLGEHDGIANFTVGQRKGLGIAYPYPLYVVALDPVKNTVIVGPSSSLVKTQLFLRDLNWLSKDQIPEHGLSASVRLRSSSSAVQATISRSAKDGKGRVVLHEGCVVSPGQACVIYDNERLLGGGWILNQVRYSETA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AVPX_ARATH
Sequence: MMMDEDVEQATLVSYSDKPRTFPDMRSKTYSPLIIRILRNLNVRALSVLLLLSFGGIFYMGARTSPIIVFVFVVCIISFMLSVYLTKWVLAKDEGPPEMVQISDAIRDGAEGFLRTQYGTISKMAFLLAFVILCIYLFRNLTPQQEASGLGRTMSAYITVAAFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFYVWLDVDSPGSMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEHGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIAAEIISAMILGGTMAQKCKIEDPSGFILFPLVVHSFDLVISSIGILSIKGTRNASVKSPVEDPMVVLQKGYSLTIILAVLTFGASTRWLLYTEQAPSAWLNFFMCGLVGIITAYVFVWISRYYTDYKYEPVRTLALASSTGHGTNIIAGVSLGLESTALPVLVISVAIISAFWLGNTSGLIDEKGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESVREITDVLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFANVSFKEVDIAIPEVFIGGLLGAMLIFLFSAWACAAVGRTAQEVVNEVRRQFIERPGIMDYKEKPDYGRCVAIVASSALREMIKPGALAIISPIAVGFVFRILGYYTGQPLLGAKVVAAMLMFATVCGILMALFLNTAGGAWDNAKKYIETGALGGKGSDSHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLVMAPIFL
What are the official names of this protein?
Pyrophosphate-energized membrane proton pump 3, AVP1-like protein 2, Pyrophosphate-energized inorganic pyrophosphatase 3, H(+)-PPase 3.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: TRPF_THEMA
Sequence: MVRVKICGITNLEDALFSVESGADAVGFVFYPKSKRYISPEDARRISVELPPFVFRVGVFVNEEPEKILDVASYVQLNAVQLHGEEPIELCRKIAERILVIKAVGVSNERDMERALNYREFPILLDTKTPEYGGSGKTFDWSLILPYRDRFRYLVLSGGLNPENVRSAIDVVRPFAVDVSSGVEAFPGKKDHDSIKMFIKNAKGL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.