PharMolix/UniProtQA huggingface dataset:
Protein: SYE_SHEB5
Sequence: MTTKTRFAPSPTGFLHVGGARTALYSWLQARANNGEFVLRIEDTDIERSTQAACDAILEGMNWLGLTWDEGPYYQTKRFDRYNEIIAQMLAKGTAYKCYCSRERIDALREAQAANGEAQKYDGCCRDLPARDTDEPFVVRFKNPIGGSVVFDDHVRGRIEFSNDALDDLIIARTDGVPTYNFCVVVDDWDMGITCVVRGEDHINNTPRQINILKALGAPIPEYAHVSMILGDDGAKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFSLEEMKQYFKLGDINKAASAFNTDKLVWLNQHYIKSLAPEYVATHLQWHMDDQEIDLSNGPALAEVVTALAERAKTLKELAASSRYFYEDFAEFDEAQAKKHLRGVALEPLQLVQQKLAALTDWTVEAIHQAIEDTATELDVGMGKVGMPLRVAVTGAGQSPGLDITLFLIGRSRSEQRISKAIEFVADRINS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDF9_MOUSE
Sequence: MALPSNFLLGVCCFAWLCFLSSLSSQASTEESQSGASENVESEADPWSLLLPVDGTDRSGLLPPLFKVLSDRRGETPKLQPDSRALYYMKKLYKTYATKEGVPKPSRSHLYNTVRLFSPCAQQEQAPSNQVTGPLPMVDLLFNLDRVTAMEHLLKSVLLYTLNNSASSSSTVTCMCDLVVKEAMSSGRAPPRAPYSFTLKKHRWIEIDVTSLLQPLVTSSERSIHLSVNFTCTKDQVPEDGVFSMPLSVPPSLILYLNDTSTQAYHSWQSLQSTWRPLQHPGQAGVAARPVKEEAIEVERSPRRRRGQKAIRSEAKGPLLTASFNLSEYFKQFLFPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVRHRYGSPVHTMVQNIIYEKLDPSVPRPSCVPGKYSPLSVLTIEPDGSIAYKEYEDMIATRCTCR
What is the function of this protein?
Required for ovarian folliculogenesis.
What are the official names of this protein?
Growth/differentiation factor 9, GDF-9.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: FBL14_ARATH
Sequence: MFIGIAYLGGDRQMDELPDHLVWDILSKLHTTDDRNSLSLSCKRFFSLDNEQRYSLRIGCGLVPASDALLSLCRRFPNLSKVEIIYSGWMSKLGKQVDDQGLLVLTTNCHSLTDLTLSFCTFITDVGIGHLSSCPELSSLKLNFAPRITGCGVLSLAVGCKKLRRLHLIRCLNVASVEWLEYFGKLETLEELCIKNCRAIGEGDLIKLRNSWRKLTSLQFEVDANYRYMKVYDQLDVERWPKQLVPCDSLVELSLGNCIIAPGRGLACVLRNCKNLEKLHLDMCTGVSDSDIIALVQKASHLRSISLRVPSDFTLPLLNNITLRLTDESLSAIAQHCSKLESFKISFSDGEFPSLFSFTLQGIITLIQKCPVRELSLDHVCVFNDMGMEALCSAQKLEILELVHCQEVSDEGLILVSQFPSLNVLKLSKCLGVTDDGMRPLVGSHKLELLVVEDCPQVSRRGVHGAATSVSFKQDLSWMY
What are the official names of this protein?
F-box/LRR-repeat protein 14.
Protein: WAK5_ARATH
Sequence: MKVHSLFLMAIFFYLAYTQLVKAQPRDDCQTRCGDVPIDYPFGISTGCYYPGDDSFNITCEEDKPNVLSNIEVLNFNHSGQLRGLIPRSTVCYDQQTNNDFESLWFRLDNLSFSPNNKFTLVGCNAWALLSTFGIQNYSTGCMSLCDTPPPPNSKCNGVGCCRTEVSIPLDSHRIETQPSRFENMTSVEHFNPCSYAFFVEDGMFNFSSLEDLKDLRNVTRFPVLLDWSIGNQTCEQVVGRNICGGNSTCFDSTRGKGYNCKCLQGFDGNPYLSDGCQDINECTTRIHNCSDTSTCENTLGSFHCQCPSGSDLNTTTMSCIDTPKEEPKYLGWTTVLLGTTIGFLIILLTISYIQQKMRHRKNTELRQQFFEQNGGGMLIQRLSGAGPSNVDVKIFTEEGMKEATDGYNESRILGQGGQGTVYKGILQDNSIVAIKKARLGDRSQVEQFINEVLVLSQINHRNVVKLLGCCLETEVPLLVYEFISSGTLFDHLHGSMFDSSLTWEHRLRIAIEVAGTLAYLHSYASIPIIHRDVKTANILLDENLTAKVADFGASRLIPMDQEQLTTMVQGTLGYLDPEYYNTGLLNEKSDVYSFGVVLMELLSGEKALCFERPQSSKHLVSYFVSAMKENRLHEIIDGQVMNEYNQREIQESARIAVECTRIMGEERPSMKEVAAELEALRVKTTKHQWSDQYPKEVEHLLGVQILSTQGDTSSIGYDSIQNVTRLDIETGR
What is the function of this protein?
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.  Binding to pectin may have significance in the control of cell expansion, morphogenesis and development.
What are the official names of this protein?
Wall-associated receptor kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS20_THESQ
Sequence: MPNIKSAKKRVRVSEKRRLRNKAYKTFFKNRIKEVLKAIENKEPKEVVLELTRKAQAAIDKAVSKGVIHKNQGARRKARLFEKVNEYLRTLETTQE
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: P14_ASFP4
Sequence: MADFNSPIQYLKEDSRDRTSIGSLEYDENSDTIIPSFAAGLEDFEPIPSPTTTSTSLYSQLTHNMEKIAEEEDINFLHDTREFTSLVPEETDNKPEDDEESGAKPKKKKHLFPKLSSHKSK
What is the function of this protein?
Structural protein required for transport of intracellular particles from the assembly sites to the plasma membrane (By similarity).  Binds to both ssDNA and dsDNA (By similarity).  Suppressed the activation of the cGAS/STING pathway by interfering with the recruitment of IRF3 to TBK1, which in turn suppresses IRF3 phosphorylation, decreasing interferon production (By similarity).
What are the official names of this protein?
Structural protein p14.5.
What is the protein family that this protein belongs to?
Belongs to the asfivirus structural protein p14.5 family.
What are the subcellular locations of this protein?
Virion. Note=Localizes at the surface of the intracellular virion.
Protein: LIN9_MACFA
Sequence: MAELDQLPDESSSAKALVSLKEGSLSNTWNEKYSSLQKTPVWKGRNTSPAVEMPFRNSKRSRLFSDEDDRQINTRSPKRNQRVAMVPQKFTATMSTPDKKASQKIGFRLRNLLKLPKAHKWCIYEWFYSNIDKPLFEGDNDFCVCLKESFPNLKTRKLTRVEWGKIRRLMGKPRRCSSAFFEEERSALKQKRQKIRLLQQRKVADVSQFKDLPDEIPLPLVIGTKVTARLRGVHDGLFTGQIDAVDTLNATYRVTFDRTGLGTHTIPDYEVLSNEPHETMPIAAFGQKQRPSRFFMTPPRLHYTPPLQSPIMDNDPLLGQSPWRSKISGSDTETLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTDAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCVENENLTDLISRLTAILLQIKCLAEGGDLNSFEFKSLTDSLNDIKSTIDASNISCFQNNVEIHVAHIQSGLSQMGNLHAFAANNTNRD
What is the function of this protein?
Acts as a tumor suppressor.  Inhibits DNA synthesis.  Its ability to inhibit oncogenic transformation is mediated through its association with RB1.  Plays a role in the expression of genes required for the G1/S transition (By similarity).
What are the official names of this protein?
Protein lin-9 homolog.
What is the protein family that this protein belongs to?
Belongs to the lin-9 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Found in perinucleolar structures. Associated with chromatin.
Protein: RL11_CYTH3
Sequence: MAKEITGYVKLQIKGGAANPSPPVGPALGSKGLNIMEFCKQFNARTQDKPGVLLPVLITVYTDKSFDFVVKTPPAAILLAEAAKIKKGSAEPNRVKVGSVNWDQIRTIAETKMPDLNAFKIESAMKMVAGTARSMGLTVSGKAPWEN
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: JZT8B_CHIGU
Sequence: MKTFTLIAILTCAVFVIFHAAAAEELEAQDVIETEALATLDEERLFECSFSCDIKKNGKPCKGSGEKKCSGGWRCKMNFCVKV
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Cg1a, U3-TRTX-Cg1a, Jingzhaotoxin-8.2, JZTX-8.2, Jingzhaotoxin-VIII.2, JZTX-VIII.2, Peptide F7-12.17.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 03 (juruin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOK_RALPJ
Sequence: MSSLSLAHYLVLGAVLFAISIVGIFLNRKNVIVLLMAIELMLLAVNLNFVAFSHYLGDLAGQVFVFFILTVAAAESAIGLAILVVLFRNLDTINVDDLDSLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CARA_BACAN
Sequence: MKRQLILEDGTVLIGTGFGGEIEKSGEVVFTTGMTGYQETLSDPSYCGQIVTFTYPLIGNYGINRDDFESIHPSVNGLIVNEICDHPSNFRNEISLNDYLKERNIPGLAGIDTRKLTRKIRQYGTLRGRLCNMDADVEYIVSQLKATVFTDHVKRVSTKDPYPSPGRGHRVVLVDFGMKHGILRELNKRDCDVIVVPYNTTAEEILRLSPDGIMLSNGPGDPKDVPEAIEMLKDIIGKVPLFGICLGHQLFALASGANTSKLKFGHRGLNHPVKNIATGKVAITSQNHGYAVEEESVENTELEITHVALNDGTVEGLRHKKFPAFTVQYHPEASAGPEDANDLFEDFLTMIENFKKEGEELCQNA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: ATG14_ASHGO
Sequence: MQCTICHRPSTVWYCAHCVNTSPKLILRYKLELTQICEEVTEMRDIVTSTLENAISEKEGLLGKHMERLQHLRLKRYNARLSHRARELEQHLDSKLSRRDGLRRALKQLSPDVAVVPAEDPDEYRELRHKLTLLQNVVSMKSTQKFEELCQWFVFTCSTTEDDHFPYSIRFIPVCNIRNWRLLSTAQESLQHMCEFVIYASRALLVDIPFGSHSEKLTTDHIAAVSHFTVNLLTILIKRKRLQERPDVPDLLGRYDIDGLLYLLCSGGDVESITGTCPPTYKVVHEFVRTALEDGDQSEERGHWMVLE
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I.  This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure.  ATG14 mediates the specific binding of the VPS34 PI3-kinase complex I to the preautophagosomal structure (PAS) (By similarity).
What are the official names of this protein?
Autophagy-related protein 14.
What is the protein family that this protein belongs to?
Belongs to the ATG14 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: GLL2_CHICK
Sequence: MRILYLLFSLLFLALQVSPGLSSPRRDMLFCKGGSCHFGGCPSHLIKVGSCFGFRSCCKWPWNA
What is the function of this protein?
Potent antibacterial activity against the Gram-negative bacterium E. coli ML-35, and against the Gram-positive bacterium L. monocytogenes EGD.  Lacks antifungal activity against C. albicans.
What are the official names of this protein?
Gallinacin-2, Gal-2, Beta-defensin 2.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule.
Protein: EGLB_ASPOR
Sequence: MKFRNLFFAAVAGSAVAAPLAKEQKKRDSVFQWIGANESGAEFGENNLPGVWGTDYIFPDVSAITTLIDKGMNIFRIQFKMERLVPDSMTGAYDEAYLQNLTTVVNAVTDAGVHAILDPHNYGRFNGEIMSTPSDFQTFWKNLAGQFQSNSLVIFDTNNEYHDMDQELVLNLNQAAIDGIREAGATEQYIFVEGNSYTGAWTWTDVNDNMKNLEDPQDKIVYQMHQYLDSDGSGTSETCVSGTIGQERVTSATQWLKDNKKVGIIGEFAGGNNDQCKTAVKGMLDYLAENTDVWKGALWWAAGPWWGDYMYSLEPPNGVAFTGMLDVLQAYLG
What is the function of this protein?
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan.  Involved in the degradation of complex natural cellulosic substrates (By similarity).
What are the official names of this protein?
Probable endo-beta-1,4-glucanase B, Endoglucanase B, Carboxymethylcellulase B, Cellulase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAA_SHEPA
Sequence: MAVSLWQQCIARLQDELSAQQFSMWIRPLQAEMEGDTLVIYAPNRFVLDWVRDKYLNIINQFFTEQMGSDAPSLRFDIGSRPSAKPVVQATAAVRTSRPVTREVTKPSFNTPHAEPMANANHRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDKYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_BACFN
Sequence: MNFTLLVVVLLTAIAFVGVVIALSNAISPRSYNAQKFEAYECGIPTRGKSWMQFRVGYYLFAILFLMFDVETVFLFPWAVIARDLGPQGLISILFFLVVLVLGLAYAWKKGALEWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHSTF_HUMAN
Sequence: MRHCINCCIQLLPDGAHKQQVNCQGGPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEVRTEGNENWGGFLRFKKGKRCSLVFGLIIMTLVMASYILSGAHQELLISSPFHYGGFPSNPSLMDSENPSDTKEHHHQSSVNNISYMKDYPSIKLIINSITTRIEFTTRQLPDLEDLKKQELHMFSVIPNKFLPNSKSPCWYEEFSGQNTTDPYLTNSYVLYSKRFRSTFDALRKAFWGHLAHAHGKHFRLRCLPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVEDYLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLDYSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKVFQFLNLGPLSEKQEALMTKSPASNARRPEDRNLGPMWPITQKILRDFYRPFNARLAQVLADEAFAWKTT
What is the function of this protein?
Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units.  It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate.  May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.
What are the official names of this protein?
Carbohydrate sulfotransferase 15, B-cell RAG-associated gene protein, hBRAG, N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase, GalNAc4S-6ST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Note=A small fraction may also be present at the cell surface, where it acts as a B-cell receptor.
Protein: A1AT5_MOUSE
Sequence: MTPSISWCLLLLAGLCCLVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHNSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIVEAVKKLEQDTVFVLANYILFKGKWKKPFDPENTKQAEFHVDESTTVKVPMMTLSGMLDVHHCSTLSSWVLLMDYAGNATAVFLLPDDGKMQHLEQTLNKELISKFLLNRRRRLAQIHIPRLSISGNYNLETLMSPLGITRIFNSGADLSGITEENAPLKLSQAVHKAVLTIDETGTEAAAATVLQGGFLSMPPILHFNRPFLFIIFEEHSQSPLFVGKVVDPTHK
What is the function of this protein?
Does not inhibit elastase or chymotrypsin.  No target protease has been identified to date.
What are the official names of this protein?
Alpha-1-antitrypsin 1-5, Alpha-1 protease inhibitor 5, Serine protease inhibitor 1-5, Serine protease inhibitor A1e, Serpin A1e.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RHAM_SHISS
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKARNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_ACIJB
Sequence: MSMVYINIFLAFIMSLMGLLMYRSHLMSSLLCLEGMMLSLFIMMTMVVLNNHFTLASMTPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PDXH_XANOM
Sequence: MTDLYAEALATFAALYAEAQNSAELEASAMTLATANVDGRPSARTVLLKAFDARGFVFYSHLDSAKGRDLQTHPQAALLFLWRSLREAGIQVRIEGGVQLVSADESDAYFASRPRMSQIGAWASLQSQTLGSRAEFDAAIAKVEATFEGREVPRPEGWGGFRVVPQAFEFWYGAKFRLHERWRYEADAASHWSKRMLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: AGRF2_MOUSE
Sequence: MIPAHWLYCLMLLLPIESCRILCQASSKSKEKVTSRPHDVCDGVCNNNGTPCFQSCPPDSEGNMKFACKAKKWHKVTETCHTLNTHSIFEEDKELYSVQSSDSTIRTHMFHRELKTIMDTLMEKCPKDLSCVIKGIERSPRMPGNIAVVVQLLHNISTTLTKDVNEEKMQSYSAMANHILNSKSISNWTFIQDRNSSCVLLQSIHSFASKLFMKEHLINISHVFIHTLGTVVSRGSLGKNFTFSMRINETSDKVTGRLLLSPEELQKVPSAFQVISIAFPTLGAILEASLLENVTVNGLVLSVILPEELKNISLIFEKIRKSGERKSQCVGWHSLESRWDWRACKTIQENSRQAVCRCRPNKLYTSFSILMSPNTLESPVLTYITYIGLGISICSLIICLAIEVLVWSQVTKTEISYLRHLCIANIAATLLMADAWFIVASFLSGPVLHHNGCVAATFFVHFFYLSVFFWMLAKALLILYGILIVFHTLPKSCLVASLFSVGYGCPLVIAIITLAVTEPGKGYLRPEACWLNWDMTKALLAFVVPALAIVVVNLITVTMVIIKTQRAAIGSSMFQEVRAIVRICKNIAILTPLLGLTWGFGIATVINGHSLAFHIIFSLLNALQVSPDAAVDSELRECVHRFCG
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Adhesion G-protein coupled receptor F2, G-protein coupled receptor 111, G-protein coupled receptor PGR20.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IBPA_ECOL5
Sequence: MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABV_PSEPG
Sequence: MAIIHPKVRGFICTTTHPKGCELNVRDQIEATRKLGVREDGPKKVLVIGASSGYGLAARITAAFGFKADTLGVFFEKPGTETKAGTAGWYNSAAFDKFAKAEGLYSKSINGDAFSDEARAKVIELIKNEMGGKVDLVIYSLASPVRKLPQTGEVIRSALKPIGEPYKSTAIDTNKDTIIEASIEPATEQEIADTVTVMGGQDWQLWIDALAGANVLAEGARTVAFSYIGSDITWPIYWHGALGQAKQDLDETALRLDQKLADEVKGGANVAVLKSVVTQASSAIPVMPLYLSMVFKIMQEKGIHEGTQNQLDRMYRDRMYRADGAPADVDEKGRLRLDDWELRDDVQTACKALWPQVTTENLFELTDYAGYKKQFLNLFGFERADVNYDEDVATDVKFDCIEL
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: RSMG_RHOCS
Sequence: MSNTRLPAPSFRATDFQAAFGVSRETLDRLAAYEALLRKWNPAINLVARSTLDDVWERHFADSAQLFALLPEGTRVLVDLGSGAGFPGLVLAILGVPEVHLIESDGRKAAFLREVARVTGAPATVHAQRAEQAEAPPADAVSARALADLSALLPLAARFLRPGGICLFPKGRTAADELTRARDSWTMRVEEFPSRTDPSGALLRLSEIAPRGMQIG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCAM_MESAU
Sequence: MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVINQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
What is the function of this protein?
Essential for biosynthesis of the polyamines spermidine and spermine.  Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: ATG18_ASPTN
Sequence: MAMNFVTFNQDYSYLAVATSKGFRIFTTDPFAKSYETKEGNIAIIEMLFSTSLVALILSPRRLQITNTKRQSTICELTFPTTVLAVKLNRKRLVIVLEDQIYLYDIQTMKLLYTIETSPNPNAICALSPSSDNCYLAYPLPQKAPPSSFNPPSHAPPGSTHVSPTTGEVLIFDALKLEAINVIEAHRSPLACITLNSDGTLIATASDKGTIIRVFSVPDGHKLYQFRRGSIPSRIYSMSFNTTSTLLCVSSSTETIHLFKLSHQTSSREGSPSSALSRERAASQSSLGTSPDPDDPTDDMESSEIASRKHNGTLMGMIRRTSQNVGSSFAAKVGGYLPKGVSEMWEPARDFAWIKLPKTNQTAGANGNAGSLRSVVAMSNNTPQVMVVTSDGNFYVFNIDLSKGGEGTLTKQYS
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct atg9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.