PharMolix/UniProtQA huggingface dataset:
Protein: NTRB_KLEOX
Sequence: MATGTLPDAGQILNSLINSILLVDDDLAVHYANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIGLMQESLAAGQGFTDNEVTLVIDGRSHILSLTAQRLPEGYILLEMAPMDNQRRLSQEQLQHAQQIAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALMEYTKVIIEQADRLRNLVDRLLGPQHPGMHVTESIHKVAERVVKLVSMELPDNVKLVRDYDPSLPELPHDPDQIEQVLLNIVRNALQALGPEGGEITLRTRTAFQLTLHGVRYRLAARIDVEDNGPGIPSHLQDTLFYPMVSGREGGTGLGLSIARSLIDQHSGKIEFTSWPGHTEFSVYLPIRK
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Under conditions of nitrogen limitation, NtrB autophosphorylates and transfers the phosphoryl group to NtrC.  In the presence of nitrogen, acts as a phosphatase that dephosphorylates and inactivates NtrC.
What are the official names of this protein?
Sensory histidine kinase/phosphatase NtrB, Nitrogen regulation protein NR(II), Nitrogen regulator II, NRII.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_METBF
Sequence: MSYIEKTDPELFEAIKKEAERQEYKLNLIASENYASKAVMEAQGSILTNKYAEGYSGKRYYGGCDFVDIAEDLAIARAKKIFNAGYVNVQPHSGSGANMAVYFSVLKPGDTIMSMDLSHGGHLSHGSPVSFSGKLFNIVPYGVSKKTEMLDYSELMKKAKENKPQMIVCGASAYPREIDFKQFREIADEVGAYLLADIAHIAGLVVAGVHPSPVPYADFVTSTTHKTLRGPRGGIIISKTEELATRINKAVFPGLQGGPLMHIIAGKAVAFKEAMSEKFKQDQVQTVKNAKTLCKCLKEKGFDMVSGDTDNHLMLVNLNNMNITGKDAEAALSKAGIIANKNTVPFETRSPFITSGVRLGTPACTTRGMKETEMELIADYIETAITNSENDKILSETSDKVRELCSRFPVYC
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  Appears to be specific for THF as the pteridine substrate, since the use of tetrahydromethanopterin (H4MPT) is much less efficient.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.  Thus, is able to catalyze the cleavage of L-allo-threonine and L-threo-beta-phenylserine.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2FA_ARATH
Sequence: MSNCLQLNTSCVGCGSQSDLYGSSCRHMTLCLKCGRTMAQNKSKCHECGTVVTRLIREYNVRAAAPTDKNYFIGRFVTGLPNFKKGSENKWSLRKDIPQGRQFTDAQREKLKNKPWILEDETGQFQYQGHLEGSQSATYYLLVMQNKEFVAIPAGSWYNFNKVAQYKQLTLEEAEEKMKNRRKTADGYQRWMMKAANNGPALFGEVDNEKESGGTSGGGGRGRKKSSGGDEEEGNVSDRGDEDEEEEASRKSRLGLNRKSNDDDDEEGPRGGDLDMDDDDIEKGDDWEHEEIFTDDDEAVGNDPEEREDLLAPEIPAPPEIKQDEDDEENEEEEGGLSKSGKELKKLLGKANGLDESDEDDDDDSDDEEETNYGTVTNSKQKEAAKEEPVDNAPAKPAPSGPPRGTPPAKPSKGKRKLNDGDSKKPSSSVQKKVKTENDPKSSLKEERANTVSKSNTPTKAVKAEPASAPASSSSAATGPVTEDEIRAVLMEKKQVTTQDLVSRFKARLKTKEDKNAFANILRKISKIQKNAGSQNFVVLREKCQPKPGKRESRVNKLNIRSNLQPRKMELVTEDEIRKVLMEKKQLTTLELVMRFKERLTTTEDKDSFSHILKKIAKLQKNPGSEKFVVVLRDNVTPLASDLTRLSIS
What is the function of this protein?
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.  It promotes transcription elongation (By similarity).
What are the official names of this protein?
Transcription initiation factor IIF subunit alpha, TFIIF-alpha, General transcription factor IIF subunit 1, Transcription initiation factor RAP74 homolog, AtRAP74.
What is the protein family that this protein belongs to?
Belongs to the TFIIF alpha subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGB_PSEPG
Sequence: MTLDRDAASHVAEVLSEALPYIRRFVGKTLVIKYGGNAMESEELKTGFARDIVLMKAVGINPVVVHGGGPQIGDLLKRLSIESHFIDGMRVTDSATMDVVEMVLGGQVNKDIVNLINRHGGSAIGLTGKDAELIRARKLTVSRQTPEMTTPEIIDIGHVGEVVSVNTDLLNMLVKGDFIPVIAPIGVGANGESYNINADLVAGKVAEALKAEKLMLLTNIAGLMDKQGQVLTGLTTEQVNELIADGTIYGGMLPKIRCALDAVQGGVNSSHIIDGRVPNAVLLEIFTDSGVGTLITNRKPR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_STAEQ
Sequence: MIKKNKEELNDMEYLVTQENGTEPPFQNEYWNHFEKGIYVDKLSGKPLFTSEDKFESNCGWPSFSKALNDDEIVELVDKSFGMIRTEVRSEKANSHLGHVFNDGPKEKGGLRYCINSAAIQFIPYDKLEELGYGDLIKHFKK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: MOAC_STAEQ
Sequence: MTNFTHINKQGNAKMVDVSNKEITKRVAEAHSSIIVNEKIYSQITQNTNSKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDISFKWDSNNDDSYRLNITAVVSTTGKTGVEMEALTAASVTALTIYDMTKAIDKGMIIGETYLESKSGGKSGDFHRKN
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CLPB_VIBPA
Sequence: MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLDVDVTHLRSKLGEMLDRLPKVSGIGGDVQLSSSMGTLFNLCDKVAQKRQDSYISSEVFLLAALEDRGPLGQLLKEVGLTEQKVSQAIEKIRGGQKVNDPNAEELRQALEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIVNNEVPEGLRGRRVLSLDMGALVAGAKYRGEFEERLKSVLNELAKEEGNVILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQKVLVDEPTVEDTVAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASSIRLQIDSKPESLDKLERKIIQLKIEQQALSNEHDEASEKRLQALNDELNEKEREYAELEEVWNTEKAALSGTQHIKSELEQARMDMEFARRAGDLNRMSELQYGRIPELEKQLDLATQAEMQEMTLLRNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLLRMEDVLHNRVVGQSEAVAVVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLASFMFDSEDAMVRIDMSEFMEKHSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSSRIQENFATLDYQGIKSEVMDVVSKHFRPEFLNRVDEIVVFHPLGQEHIKSIASIQLERLAKRLEEKGYQLEVSDKALDLIAQVGFDPVYGARPLKRAIQQNVENPLAKSILAGEIVPDKKVQLIVTNDQILAHQ
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_AGRVS
Sequence: MNTVASLFAILPYPQIDPIALSIGPVAIRWYGLAYVTGILIGWWLARRMIANLSLWPGNTTPITEKHLDDFLVWAAIGIVLGGRIGYILFYDLQPVLDNPLVALEIWRGGMSFHGGLTGATLAMIVFARRNGLPVWMLFDLVACVAPIGLFFGRIANFINGELWGRVSDVAWAMQFPTGGPFTRHPSQLYEAALEGLVLFVLLQVLARQFHALKTSGVISGVFICGYALARIFVEFFREPDEQLGYLVGGWLTMGMLLSLPMLALGLWAIWRARRAGRSQEPSGLKG
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBD_AETCO
Sequence: MTIALGKFTKDEKDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFALIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SRP54_THEVO
Sequence: MVLESLSSSLRETIRKITGSTYIDKNTVKEISKDLQRILLKADVNVQTVLNITKEMERRALEEKPPVGMAHQDYMVKIIYEELLKILGEPSNVELKPQTIMLVGLYGHGKTTSAGKLSRFFMKKGLSAGLIAADVHRYAAYEQLQQIAESVNAKFYGDPKEKDPVKIIKNGLEVLKDAQVKIIDTSGRDSLDSDLIEEIRRIKEAVKPDQVLMVIDATMGQQAGPESKAINDAVGVTGIIITKMDGTAKGGGALSAVAKMRVPIYFIGTGEHMDDMEIFDPKKFLSRLLGLGDLETLFETVKEANITEEEAQKSFEKLMTGKFNLKDMYDVWEKFSRPGLMKKLVDSLPLAKLPGSQKINDDQILTAEQKLQRYRIIMDSMTFQELENPEIINAKRITRIARGAGVREEDVRMLLKEFKAMKNNMKLMKGNRGFKKILQSNFRSGNFGLDDLGLK
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: CETN4_MOUSE
Sequence: MASSQRITLDQWKKKAAKVELNDTQKQEIKEAFDLFDIDGSGTIDLKELKIAMRALGFEPKKEEVKQLIAEIDKEGTGTICFEDFFAIMSVKMSEKDEKEEILKAFKLFDDDATGSISLNNIKRVAKELGENLTEDELQEMLDEADRDGDGEINEEEFLKMMKKTSLY
What is the function of this protein?
Ca(2+)-binding protein that may be involved in basal body assembly or in a subsequent step of ciliogenesis.
What are the official names of this protein?
Centrin-4, Centrin4.
What is the protein family that this protein belongs to?
Belongs to the centrin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm. Note=Accumulates at procentrioles during their elongation. Isoform 3 is not observed in the centriole.
Protein: IMP1L_XENTR
Sequence: MIRRIVGKTLGLLGYTIQYGCIAHCAFEYIGEVVICSGPSMEPTIRNYDVLLCDNLSRHFFSIHKGDIIVAKSPDKPSVNICKRVIGLEGDKVCMSSPSALLKRHTYVPKGHVWLEGDNLDNSTDSRSYGPVPYALIRGRICLRVWPLESFGPLKESPNGRIQDNWP
What is the function of this protein?
Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space.
What are the official names of this protein?
Mitochondrial inner membrane protease subunit 1, IMP1-like protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family. IMP1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: TRUA_DESVV
Sequence: MARLRLTIAYKGTDLHGWQVQEHATRPRPRTVQGVLEPIVSRMAGEQVRLHAAGRTDAGVHADGQVAHVDIPDHKLDVDWQKAINAQLPDDICILDVRRAADDFHARFDALGKRYTYRLWLTRRFIPPKLHGQVWATGPLDVYAMDRAARHLAGTHDFAAFQNQGTDVTSTVRTVHAIRRCPSGTLPAGALLTYGEPYTSWRCTGTHPDQPPATAGHPLAGIGLELVWSFEGDGFLKQMVRNMMGLLVAVGRGALAADDVPGIMATLDRSRAPATAPACGLTLSEVYYPPCDYPYAR
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL24_PORGI
Sequence: MSKLHIKKGDTVMVISGEDKGHSGRVLEVLVKEQRAIVEGLNMIKKHAKPSAKNPQGGIISKEAPIHISNLNVVDPKTGKATRIGRRLNENGKLVRYAKKSGEEIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PURA_ARCFU
Sequence: MGATIIVGGFWGDEGKGKIVAHVAHSDKPVIIARGGVGPNAGHTVEIDGQKFGVRMIPSGFVYKDAKLLIGAGVLVNPEVFLKEVELLKVGDRARVDYRCAIIEPKHIEADKGSEHLSKKIGTTGTGCGPANVDRVNRVAKQAKDIPELKDYLADVPLEVNQAIENGQFVLIEGSQGFGLSLYYGTYPYVTSKDTTASAIASDVGVGPTRVDDVIVVFKCFPTRVGAGPFPTEMPQEEAEKLGIVEYGTVTGRRRRIGYWDGEFARYSAMVNGATQVAITGVDKLDKECYGVTEWEKLTPKAKKFIEQVEEDVRVPVTLISTGPELKQIIDLRKEKL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARSM_HALSA
Sequence: MELWTHPTPAAPRLATSTRTRWRRTSRCSQPWATTPGTNSSDASRTPTTASASATSKPQSASARARSVRRSPDCTPRAWSRGARKDRGATTNRPRRPKFCSKRSTTCEATMSNDNETMVADRDPEETREMVRERYAGIATSGQDCCGDVGLDVSGDGGCCSDETEASGSERLGYDADDVASVADGADLGLGCGNPKAFAAMAPGETVLDLGSGAGFDCFLAAQEVGPDGHVIGVDMTPEMISKARENVAKNDAENVEFRLGEIGHLPVADESVNVVISNCVVNLAPEKQRVFDDTYRVLRPGGRVAISDVVQTAPFPDDVQMDPDSLTGCVAGASTVDDLKAMLDEAGFEAVEIAPKDESTEFISDWDADRDLGEYLVSATIEARKPARDD
What is the function of this protein?
Catalyzes the transfer of a methyl group from AdoMet to arsenite, producing methylated arsenicals.
What are the official names of this protein?
Arsenite methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.
Protein: OLM2B_MOUSE
Sequence: MAYPLPLVLCFALVVAQVWGSTTPPTGTSEPPDVQTVEPTEDDILQNEADNQENVLSQLLGDYDKVKAVSEGSDCQCKCVVRPLGRDACQRINQGASRKEDFYTVETITSGSSCKCACVAPPSAVNPCEGDFRLQKLREADSRDLKLSTIIDLLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDVEEIRTELNKRGKENCSDNTLESMPDIRSALQRDAAAAYAHPEYEERFLQEETVSQQINSIELLRTQPLVPPAAMKPQRPLQRQVHLRGRLASKPTVIRGITYYKAKVSEEENDIEEQHDELFSGDSGVDLLIEDQLLRQEDLLTSATRRPATTRHTAAVTTDASIQAAASSSEPAQASASASSFVEPAPQASDRELLATPQTTTVFPEPTEVMPSTQVSPTTVAHTAVQPLPAMVPGDIFVEALPLVPLLPDTVGTDMPEEEGTAGQEATSAGPILSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDDRIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFNQEVIVLSKLNAVDLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY
What are the official names of this protein?
Olfactomedin-like protein 2B, Photomedin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: TYSY1_BACSH
Sequence: MTQFDKQYNSIIKDIMNNGISDEEFNVRTKWDSDGTPAHTLSVISKQMRFDNSEVPILTTKKVAWKTAIKELLWIWQLKSNDVTELNKMGVHIWDQWKQEDGTIGHAYGFQLGKKNRNLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPDELDSMALTPCVYETQWYVKQGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYELGEYIFNIGDCHVYTRHIDNLKIQMEREQFEAPELWINPEVKDFYDFTIDDFKLFNYKHGDKLLFEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase 1, TS 1, TSase 1, Thymidylate synthase A, TS A, TSase A.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_ESCF3
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_ALKMQ
Sequence: MKSITVEKLMKDLNMEELNSIEATALLISTTDLNRPGMQLAGFFDYFAYERIQIIGKVEHRYLETLDTKTRKERLDRMMSYDIPCLIISRGLEVPEELLCTANKYQRKILRSHKNTTKLISKVINYLEDTLAPTITLHGVLMDIYGVGVLITGKSGIGKSETAVELIKRGHLLVADDAVEIKRIGHEVLQGCAPEIIRHMIEVRGIGILDVKSLFGVGAIKIKTDIDLIIDLEEWDSTKSYDRLGLDDNHREILGMKIDEVTIPIKPARNIALIIEVAARNHRQKKMGYHAAQEFNDRLMKSLEEKSQQ
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: HSFA5_ARATH
Sequence: MNGALGNSSASVSGGEGAGGPAPFLVKTYEMVDDSSTDQIVSWSANNNSFIVWNHAEFSRLLLPTYFKHNNFSSFIRQLNTYGFRKIDPERWEFLNDDFIKDQKHLLKNIHRRKPIHSHSHPPASSTDQERAVLQEQMDKLSREKAAIEAKLLKFKQQKVVAKHQFEEMTEHVDDMENRQKKLLNFLETAIRNPTFVKNFGKKVEQLDISAYNKKRRLPEVEQSKPPSEDSHLDNSSGSSRRESGNIFHQNFSNKLRLELSPADSDMNMVSHSIQSSNEEGASPKGILSGGDPNTTLTKREGLPFAPEALELADTGTCPRRLLLNDNTRVETLQQRLTSSEETDGSFSCHLNLTLASAPLPDKTASQIAKTTLKSQELNFNSIETSASEKNRGRQEIAVGGSQANAAPPARVNDVFWEQFLTERPGSSDNEEASSTYRGNPYEEQEEKRNGSMMLRNTKNIEQLTL
What is the function of this protein?
Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
What are the official names of this protein?
Heat stress transcription factor A-5, AtHsfA5, AtHsf-12.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYFB_LEPBJ
Sequence: MKLSLDWMNDFTPLKEVGLDVILKKIAVSVCEIDGVVPFRPELDFVKIVRIESLDKHPSADKLQIAEVFDGSSKSQIVTGATNVKVGDLVPLAIPGAKLGDREILESELRGVKSSGMFCSEKELSLSEESSGVWILNGIEGAEIGKTIRSFLYYEDIIFEIDNKSITHRPDLWSHFGFARELASQLRLPITFNPFESLWNFDLSMKFPRVLENQNAHSYYASSICEVFVIPSKRKFQSRLQKCGIRVINNVVDVSNYVMLEMGQPTHFFDKRFLESQGGVSLEVSYAKKGESFALLDETSPSLEEEILLIRNQGRPVAVAGVMGGKESAVQNNTTEIVMESAVFAREKIRKSIRSTGIRSDSSVRYEKGLEATTTLPVIRRALNLLKENGCPSLKASEPVGFLHTPHKEVRIHTDIHFINTKLGITLSQGDITDILERLHFMVSWKGDRLEALVPKFRHNYDVTIPEDLVEEIGRTRGYDTIQVTPLLAEIKTPIRNLSRELERKCKTFFSVGLGYHEVYNYSFQALKENELDGDVELSVKIRNEMPEEQSVLRNSLISSLLKNIRTNQDRFSEIKIFEFGRAYFNIPEPDNEKKFFSFAVSFDRKSSESDLGLLEDDFLKVRKEIESFLKYIRIFEYFWDIKPEIFFHPGASLSLIVDSKQIGNLGYVHPAVLDSFELKKRVIYGSLEFEKLVEIWNTNRNISRFNVPSQFPEAEIDISILIGEKENTNLFTDLVRREKIPELQEGWVYSQFAGGSVPVGKRSVSYRFRLVNYEKTFTQERIKEISDHLVALAGKNGFVLR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_LEGPN
Sequence: MSNVRLIARLDIKGPNLIKGVHLEGLRVVGNPNEYAMAYYAQGADELIYMDTVASLYGRNNLSEIVKTTAENVFIPITVGGGIRSVDDAEQLLRCGADKVAINTAATKNPTLISDIARRFGSQCVVLSIEAKRTVNGRWEVMTDNGREHTGMDVVDWARNGEKFGAGEILLTSIDQEGTRKGFDLELVKQVSSMVSIPVIASGGMGKLEEFN
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_PORGI
Sequence: MADRRRTDDNKGAREVVLLLNIGSPDSPEEKDVARYLNSFLTDRRIITLPFLLRQLLVRGIITPFRKKSSAQKYRTVWDESTRSFPLISHTKAIARALAHTGREVHVAMRYGKPAVADVLKELPHGRSLVVLPLFPHYAMSSYETAVEHCKAEIRRLCPNLSFRVVQPFYAHEAYIRVLADNIRPYLTKPFDKLILSYHGIPRDHLDKTTRQALNLRHPEGCCTEEDPTANVCYRYQTYRTTALIREALGLAEEQVEQVFQSRVGHTEWLRPYLIERLSAWPQEETKRILIACPSFVCDCLESLEEVADHGQSIFKKAGGADFTYIPCLNSGANWIDALRNILEE
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_LACSA
Sequence: MKIRASVRKICEKCRLIRRRGRIRVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRUA_SHELP
Sequence: MRVALGIEYDGSRYFGWQRQAEVDSVQAQLERALSFVANEPISIQCAGRTDAGVHATGQVVHFETNAVRKESAWTLGVNVNLPDDIAVRWAKDVDDEFHARFTATARRYRYMIYNHQFRPGILRSGVSHYPGQIDEAKMHEAAQFLLGEQDFTSFRAIQCQSNTPFRCVHEVNVTRQGMYICVDIKANAFLHHMVRNIVGSLLEVGYGRQPVSWIKELLALKDRTQAAATAKPNGLYLVDVTYPEHYALPKLALGPLFMLD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PALI_EMENI
Sequence: MLLKPATPLTILLLIAFVLLLLSVISTPIVKSIPLATFDNVEYGVFGYCKAGTCTAIHIGYTTEEIENTGSTDSDFNLPSDARRSLSSILIVHPIAAFLTLICLCLAAAAHLHAPSHSPRYLLALLILLLPTLLVSLLAFLVDILLFVPHLSWGGWIVLAATIILVTCGVVTCAMRRTLVSRKARKRRIAENAEMSGQNYYNRQNAAAAALNESKPIAPEAKETFVAATQSSESGPTFATFRTNTRSSDDDRTPLNNHSDPSAQDAGYQSRIPGDPVPYNAPRDDFGNPLPPGAYNSAPRMRTPGPPGPPPPDSRVRDQYSDPRRGPPTGFAPRGRGGYPPRGGYGRGGPYGGPYGPNSRAPLTGRGGYMGPMRGGPAGPMARGGYRPQPAAGGYGNARAMGEDEYGYRGPSSRQRTPGPMAAPAAPGPAGQAIEMMPQPRHEPDAQDEVPEQQQLHAISIDNQHEPVSPTSLYSRTQSYVPPRRNWGPQAYQSSEPNLPYQPNQPRHARSQSGSMYYEDEDPVYTSRNESAVGNSGVPSVLTPGNSAK
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor pacC in response to alkaline ambient pH.  Might be a pH sensor.
What are the official names of this protein?
pH-response regulator protein palI/RIM9.
What is the protein family that this protein belongs to?
Belongs to the palI/RIM9 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.