PharMolix/UniProtQA huggingface dataset:
Protein: Y2366_LISIN
Sequence: MWGYVHLISWVAIVVLTVTALLIYSKSVKGFTMLQMINRVFYILVILSGIMMVQYSVKESWILAIFKILMGIIVIGVVEMLLSYRKQQKPTGMFLMIFIIVVVITVSLGFYLSGGYPLFN
What are the official names of this protein?
UPF0344 protein lin2366.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIR2A_MYCTO
Sequence: MTGKLVERVHAINWNRLLDAKDLQVWERLTGNFWLPEKIPLSNDLASWQTLSSTEQQTTIRVFTGLTLLDTAQATVGAVAMIDDAVTPHEEAVLTNMAFMESVHAKSYSSIFSTLCSTKQIDDAFDWSEQNPYLQRKAQIIVDYYRGDDALKRKASSVMLESFLFYSGFYLPMYWSSRGKLTNTADLIRLIIRDEAVHGYYIGYKCQRGLADLTDAERADHREYTCELLHTLYANEIDYAHDLYDELGWTDDVLPYMRYNANKALANLGYQPAFDRDTCQVNPAVRAALDPGAGENHDFFSGSGSSYVMGTHQPTTDTDWDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit beta nrdF1, Ribonucleotide reductase R2-1 small subunit, Ribonucleotide reductase small subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: G6PI_RHIL3
Sequence: MNAIVEQLKSTADATKATDIRAAFAADSQRFSRFSVSLDDLLMDFSKTAVNDDILKLLVKLAEEGGVEKKREEMFSGKAINFTEDRAVLHTALRNRSNAPVLVDGKDVMPDVNAVLAAMGKFADDVRSGTLKGATGKAITDVVNIGIGGSDLGPVMATLALAPFHDGPRAHFVSNIDGAHIADILKLVQPETTLFIVASKTFTTVETMTNAQTARNFIAKALGEAAVQHHFAAVSTALDKVAAFGIDSARVFGFWDWVGGRYSIWSAIGLPLMIAVGPENFGKFLDGAHAVDNHFRKAPITENLPILLGLIGFYHRNVLGYPTRAILPYDQRLSRFPAYLQQLDMESNGKGVTIDGTPVEGNSGPVVWGEPGTNGQHAFYQLIHQGTSIIPAEFMIAANAFEPELRHQHQLLISNVLAQSEALMKGRTFAEAKKQLTDKGMDDKKADFIAPHRVFTGNRPSITFVYDKLTPYALGRLIALYEHRVFVEGVLFRINSFDQWGVELGKELATGLLPVVEGKESAASHDSSTQGLVAALAKLAK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBB_CUPPJ
Sequence: MQANSRAYFLLIAFISFGLVGFALYLQFEKGYQPCPLCIMQRFAFIGIGLFSLLAVIAQNTRSLWQGLGMLSGVGGIAVAVYHVSLLLNPKASCGIDPLENWVNALPTAKVLPQVFYSDGLCTAPLPPVLGLSVPAWSLIWLFILTLTLAVGLIRREKNFR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYP_HALS3
Sequence: MSDDDQELGITESKEHSPGDWYAEVVQKAGLADYAPMGGFIVTRPRGYALWEAIQDNLDGWFKDTGVENAYFPMFIPEDYLEREKDIVEGFDPEVAWVTQGGHDDLDQRLAVRPTSESIIAPYLSQWVRSHRDLPLRVNQWNSVVRWEATETKPFFRTKEFLWQEGHTAHATDEAAWAETTLRLDQYHRLYEDVLGIPVLRGRKPDHDKFPGADTTMSVEALMPDGKSVQGGTSHHLGQSFADAFDITFADEDEAERTAYTTSWGLSWRAIGALVMSHSDDQGLVLPPTVAPKQVVIVPIWQEDTKDDVEQYGAEIAAELEAQGVRVHFDDRDGRNPGFKFNEWELNGVPVRFEIGPNEVEDDEVTVVHRPDGESTVEDRAAIADRVHDHLDEVYDKLYDAAADRLAENVREADNRADILGTIGQHGGYVKAPWCGDQDCEAEIKDQIAAEIVMVPLGEDSAARAASELEGERVPEPDHDGEDCAICGDEATRTAYFAKSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1041_SACS2
Sequence: MSYLVVTIKVILITGMPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGERLMDFAKRLREIYGDGVVARLCVEELGTSNHDLVVFDGVRSLAEVEEFKRLLGDSVYIVAVHSPPKIRYKRMIERLRSDDSKEISELIRRDREELKLGIGEVIAMADYIITNDSNYEEFKRRCEEVTDRVLKNG
What are the official names of this protein?
UPF0200 protein SSO1041.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: RK2_MESVI
Sequence: MGIRLYKAYTPGTRNRSVLEFNDITKTNPEKSLTYHRHRSKGRNNRGIITIRHRGGGHKRLCRLIDFTREKNIPATVASIEYDPNRNCRIALLYYKNGIKRYIIHPRGLSVGKEIVSSVEAPLSVGNSLPLNKIPLGTGIHNIELSPGQGGQLARAAGAVAQLIAKEGKFVTVRLPSGEVRLILKECWATIGQVGNVDANNITIGKAGRTRWLGKRPVVRGVVMNPVDHPHGGGEGRSPIGRPKPVSPWGKTALGAKTRKRKKYSDVLIIRRRKSA
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MENF_ECOLI
Sequence: MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWLASQQTYPQFYWQQRNGDEEAVVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDPSQGNLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIQAKEFIATLVSIKPLPGLHLTTTREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVICLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKISGNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME
What is the function of this protein?
Catalyzes the conversion of chorismate to isochorismate.  Can also catalyze the reverse reaction, but with a lower efficiency.
What are the official names of this protein?
Isochorismate synthase MenF, Isochorismate hydroxymutase, Isochorismate mutase.
What is the protein family that this protein belongs to?
Belongs to the isochorismate synthase family.
Protein: CDPF1_XENLA
Sequence: MDLEESRPKGVFECELCRLSVPYTYFGQRPPNSHSVVLLEQCFITKDPFTPDKEKFLILGSPCSLCEKAVCVGTECSLFYSKRFCLPCVLQHRDDFPPEIQQEVDKRKAQKKS
What are the official names of this protein?
Cysteine-rich DPF motif domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CDPF1 family.
Protein: DNLJ_PELTS
Sequence: MTQDLERARERAEELRREIEHHNYLYYVLDRPAITDAQYDRLMRELERLEKQFPALVTPYSPTQRVGGRPREGFAAVRHLSPMLSLANAFDERELRDFDRRVRQALPGEQVRYVVELKIDGLAVSLYYENGILVRGATRGDGDTGEDITENLKTVRSVPLRLRRPVPALEVRGEAFMPKEAFSRLNEGREEAGETLFANPRNAAAGSLRQLDPKITASRQLDLFVYGTGYGEWGRAVFPDGERTAPQEHAEVLELLKELGFKVNPEYRLFDRLDELVEYCLGWQARRFELPYAVDGLVIKVNSLAQQERLGATMKSPRWAVAYKFPPEQAVTKVKDIFVRVGRTGVLTPTAELEPVRLAGTTVSRATLHNEDIIREKDIRIGDKVLVQKAGDIIPEVVAVLKEERTGAEKAWAMPGRCPSCGAGVVRAEGEAAVRCTNMACPARLQEGLIHFASRDAMDIAGLGPAVIAQLVSAGLVGDPADLYALRYEDLVPLERLGPKSARNLLEAIEASKGRSLARLIFALGIRHVGERAAKILANHYQSLSGLMSATQEELVNIPEIGPKIAASIVEFFSNEQNRKVIDKLVKAGVNTLTEKVIREGGGPLNGKVFVLTGVLKDFSRQQAQELIESLGGRISSSVSRNTDFVVAGENPGSKYEKALTLGVKILDENEFRELTGRK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SYA_PROMP
Sequence: MKSQTKNTPITGDEIRKEFLNFYHEKLHKIIPSASLIPDDPTVMLTIAGMLPFKPVFLGLKERPSKRATSSQKCIRTNDIENVGVTARHHTFFEMLGNFSFGDYFKKEAIEWAWELVTDIYGLSAENIIVSVFHEDDDSVKIWKEDIGIHPKRIIKLGEKDNFWSSGKTGPCGPCSELYFDFKPEKGVQNIDLEDGDRFIEFYNLVFMQYNRDPDGQLTDLKYKNIDTGMGLERMAQILQKKKNNYETDLIFPIIQKASEISKIDYYSSGERTKISLKIIGDHIRAVIHLISDGVIASNLGRGYILRRLIRRMVRHGRLLGLKNEFLSKLASVGIKLMQENYPDLKNNCDHILSEIKIEEIRFRETLERGEKLLDELISSGQKMITGFKAFELYDTYGFPLELTEEIAQENNIGVDVKGFDKEMSAQKERAKAASQIIDLTLEGSLEREIDLFDKTLFNGYDSLDSDAEIKGIFLESTLVKQASEGQKVLIVLDQTSFYGESGGQVGDIGTILSNDLEVVVDNVIRKKNVFLHYGIVKKGILSLGQKVKTKVNDLARAKAAANHTATHLLQSALKVVVNESVGQKGSLVAFNKLRFDFNSSKPITKDQIFKVETLVNSWILENHSLNIKNMAKSEALERGAVAMFGEKYDDEVRVVDVPSVSMELCGGTHVKTTSELGCFKIISEEGISAGVRRIEALSGQSAFEYFSDKNSLVSQLCDLLKANPNQLLDRVNSLQSELINKNKEIQKMKDEIAYFKYSSLSSSANKVGLFSLIISQLDGLDGNSLQSAALDLTSKLGDKSVVILGGIPDKENRKLLFVVSFGEDLVKRGMHAGKLINDISRICSGGGGGKPNFAQAGAKDIDKLNDALEYARKDLRTKLHSYSDK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHRS6_XENLA
Sequence: MGRLDGKVIVLSAAAQGIGRAAAIAFAKEGAQVIATDVNEMKLKELEAYKGIQTRVLDVTKKDQIENLCKEIDRIDVLFNVAGFVHHGTILDCTEADWDFTMNVNVRSMYFMIKTFLPKMLAQKSGNIINMSSVASSIKGVVNRCVYSTSKAAVIGLTKSVASDFIDQGIRCNCICPGTVDTPSLRERIQARPDPEQALKDFLARQRTGRMATAEEVAHLCVYLASDESAYVTGNEHIIDGGWSL
What is the function of this protein?
NAD(H)-dependent dehydrogenase/reductase with a preference for cyclic substrates (By similarity).  Catalyzes stereoselective conversion of 4-oxo-L-proline to cis-4-hydroxy-L-proline, likely a detoxification mechanism for ketoprolines (By similarity).  Mediates the formation of 2,5-dihydroxybenzoate (2,5-DHBA), a siderophore that chelates free cytoplasmic iron, thereby regulating iron transport and homeostasis while protecting cells against free radical-induced oxidative stress.  The iron-siderophore complex is imported into mitochondria, providing an iron source for mitochondrial metabolic processes in particular heme synthesis (By similarity).  May act as a 3-hydroxybutyrate dehydrogenase (By similarity).
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 6, (R)-beta-hydroxybutyrate dehydrogenase, 3-hydroxybutyrate dehydrogenase type 2, 4-oxo-L-proline reductase, Oxidoreductase UCPA, Short chain dehydrogenase/reductase family 15C member 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: NUOK_BACAC
Sequence: MSSVPASAYLTLAIILFCIGLFGALTKRNTVIVLVCIELMLNAANLNFVAFSKLGLFPNLTGQIFSLFTMAVAAAEAAVGLAILIALYRNRTTVHVDEMDTLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLME_CHESB
Sequence: MTKEKKAGSGTRVLKTRVKKKRGLKSSSRRWLERHLNDPYVRRANSEGMRSRAAYKLIEIDDKHHILAPGMKVIDLGAAPGGWCQVAAASVKSDPAKPSVVGIDYLEMDPVPGAAVLQMDFLDDAAPDRLIEVLGGSPDVVLSDMAAPTTGHRRTDHLRTMQLCEAAADFAISVLKTGGNFLAKTFQGGTEGELLSLLKRNFRSVHHVKPPASRDESVELYILAKDFKGRQAAEG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFA2_SYNY3
Sequence: MVTLIDSPTSAAVQPRLTLQTADIAAHTTAIRCLDWDRDRFDIEFELRHGTTYNSFLIRGEKTALIDTSHRKFEAVYLQLLQDLVDLRSLDYLIVNHTEPDHSGLIPDLLELAPQVTVVGSKVAIQFLEKLVHRPFESQIVKSGHSLDLGQGHELQFISAPNLHWPDTILTYDSGTQVLYTCDVFGMHYCDDSLFDETPERLEPDFQYYYNCLMGSNARSVLMALKRIAPLQVVLVATGHGPLLQHHISHWLGQYDAWSQNQVKAETFVALFYVDGYGVSDRLVQTIADGISKTGVAIELVDLSVADTHEVRTLAQCAAGLVVGMPPQSSTSTTLDPLLGTILAAVHPKQVIGLFESGGGQDEPIYPLRNRFQELGLQEAFEPILLKTEPTAATDQLCREAGTDLGQYLTQKQSQQANTDLDPELNQAIGRLSTGLYILTAQKGDVRSAMLASWVIQGSFEPLGIVIAVAKDRAIESLLHPGDTFVLNVLEEDNYQSLMRHFLLRFPPGADRFAGVNTYPAQNGSPILLETLAYLECEVTSRLDGNDHWLVYSTIQTGRVAKLNALTATHHRKLGNHY
What is the function of this protein?
Mediates electron transfer from NADH to oxygen, reducing it to water.  This modular protein has 3 redox cofactors, in other organisms the same activity requires 2 or 3 proteins (By similarity).
What are the official names of this protein?
Putative diflavin flavoprotein A 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavodoxin reductase family.
Protein: RL5_CHLCH
Sequence: MSGNNESASYASSLARLDTYYREKVVPALMERFQYKNIMEVPRLQKIAINIGVGDAAGEPKLLDVAVGELTQIAGQKPQIRKSKKAISNFKLREGQAIGCRVTLRRKAMYEFFDRFVSLAVPRIRDFRGLSDTSFDGRGNYTAGVKEQIIFPEIDIDKVPRISGMDISFVTSAKSDEEAYVLLSELGMPFKKKNN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL7_CAMJE
Sequence: MAISKEDVLEYISNLSVLELSELVKEFEEKFGVSAAPVMVAGGAVAGGAVAAAEEKTEFDIVLTDGGAKKIEVIKIVRALTGLGLKEAKDAVEQTPSTLKEGVAKAEAEEAKKQLEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SDHE_PSEPK
Sequence: MVEQTELNRLFWHSRRGMLELDVLLVPFTQEVYPTLNETDRELYVRLLSCEDQDMFGWFMERTESEDPELQRMVRIILDRVQPK
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_BURVG
Sequence: MARGKFITFEGIDGAGKTTHLQWFCERLQAKLAAGDRQVVVTREPGGTPLGEALREMLLNQPMDLETEALLMFAARREHLARVIEPALARGDWVVSDRFTDATFAYQGGGRGLPRDKLEALERWVQGGFQPDLTVLFDVAPQVASERRGAARAPDKFESETDAFFTRTRDEYLRRAQEAPHRFTIVDATQTIPEIRGRLERVLAAL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: CARP1_CANAX
Sequence: MFLKNIFIALAIALLVDASPAKRSPGFVTLDFDVIKTPVNATGQEGKVKRQAIPVTLNNELVSYAADITIGSNKQKFNVIVDTGSSDLWVPDASVTCDKPRPGQSADFCKGKGIYTPKSSTTSQNLGSPFYIGYGDGSSSQGTLYKDTVGFGGASITKQVFADITKTSIPQGILGIGYKTNEAAGDYDNVPVTLKNQGVIAKNAYSLYLNSPNAATGQIIFGGVDKAKYSGSLIAVPVTSDRELRITLNSLKAVGKNINGNIDVLLDSGTTITYLQQDVAQDIIDAFQAELKSDGQGHTFYVTDCQTSGTVDFNFDNNAKISVPASEFTAPLSYANGQPYPKCQLLLGISDANILGDNFLRSAYLVYDLDDDKISLAQVKYTSASNIAALT
What are the official names of this protein?
Candidapepsin-1, ACP 1, Aspartate protease 1, Secreted aspartic protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PNP_DESPS
Sequence: MFNKVEADIDGKLISIETGKLAKQASGSIVISCGGTVVLVTVVGAKTSNPNVDFLPLTIEYQEKFSAVGRVPGNYFRREIGRPSDQEVLTCRIIDRPLRPLFPEGYRSETQVIATVLSADQVNSPDVLALTGASAALSISHIPFAGPVAGGRIAYIDGKYVLNPTFAELESSSMDLMVACTRNAIVMVEGKADELSEDEILGAIFFAFENLQPLINLQDELQRANGLEKIVVESPVIDAELKAKVVEIAAAGMQKVYTTVDKLERGKVYDDLKKEVVAQLDTEEGLRASEISSLLSDFKKTYLREKTVNTGVRIGGRAWDEIRDISSETEYLPKTHGSALFTRGETQALVTATLGSERDKQRVETLNGETSRRFMLHYNFPPYCVGEARFLRGPSRRDIGHGTLATRGLEAVLPSEEDFPYAIRVVSEILESNGSSSMASVCGGSMAMMDAGVPLKRPVSGIAMGLIKEGEGVAILSDILGDEDHLGDMDFKVVGTCDGITALQMDIKIDGVSRDIMSNALDQAKRGRMHILEEMSKGIAEARAEVVEHAPKYFIHKISQDKIRDIIGPGGKIIKELSAQYDAKIEVDDSGLVKMFVANGALAEALVERVKSITAEVEVGAVYTGKVKTIKDFGAFVEILPGTDGLVHISELALERVKDVTDVVNEGDTIEVKVLDVDNRGRIRLSRKALLG
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REXO3_KLULA
Sequence: MYPTLNLAVCLKSSHLISSHRFCLKNSQSTEKHQKEINISVKERYTCNPSHRQKKNGWVREKNALREPLTASLKFTIHLNSIVFRYIPLYAIIMVGNPVLRPVDMKMQPAPYQDRVRVVQKIYTQLKRFQSSSPHIIKASTIWEHEVAKIAKTRQSYAFNASILLRDIVKYKGNLDKTGKPKNNSSSLIQRSHVLQKLRSLLLDEETLSRNGFFVKMYDTDPINESESDYVECYRCETKFDVTKIMEPTVCRYHLQRKVYNRETKKREFPCCGASLESYSDISAGCMKAKNHVYKWENFTKLSSVVPFKSLVDIKGEENVLALDCEMAFTSKGYEMIRITIVDFWSSEVVYDKVIKPLGEIIDLNSKFSGIHHIDDTAPTIHEAEKCYICPSMINQNSILIGHGLDNDLRVMRIVHDKVIDTAVLYPAGKYKSSLKNLSFEILSRRIQGGEHDSSEDAIAAMDVIKKKLSIPLDKKSW
What is the function of this protein?
3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA.
What are the official names of this protein?
RNA exonuclease 3.
What is the protein family that this protein belongs to?
Belongs to the REXO1/REXO3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y2093_VIBVU
Sequence: MEMSNAQRLILSNQYKLMSQLDPENAEKYQRFQTIVERGYELQMRELNKDYGCITEALCKEIIDVMEMYHAMQESFRMLDADESTQVDQRRLQFLGFDIASEAQLVHYVRFLTESEGLYPQFDKGDHHFNSQMPMLEKYRRMLATWRKCPRQYHLCATELRQIFNA
What are the official names of this protein?
UPF0304 protein VV1_2093.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: MSL2_DROME
Sequence: MAQTAYLKVTRIAMRSASNLSKRRVEELNSGLGELRQLLSCVVCCQLLVDPYSPKGKRCQHNVCRLCLRGKKHLFPSCTQCEGCSDFKTYEENRMMAAQLLCYKTLCVHLLHSALFGELAGMRPQVARELVPRIKLPPKTTQEFIREGSNISDTFDIFLPQPDLPFLKDMPTSLPAETPPTSAVTTPELPYDHHLNISDIEAEAAATAEQGHFSPLPLLPTGSRMGMLSHAGQIVIATESSESGFMDQAWTDQVDLSGTVSVSKYTNSGNNFAVSYVMPTSATTKFDPQELQIGQVVQMADSTQLAVLAAVEETVETSTQLTVLSTTVEETVETSTQLEVLTSAEEPNEISDQLANLQVEESDEALVEETVEEAEGTSIPSEVVAEHMEEDQHLDVHTSQSPTQTEMEEAVEEHVATKTQLGHVQTELQDAESLQKDFEDAKAAAEEAKEKEKDLHAISAELQKEDSDEPTLKRKRTRTLKASQAAKIEPVPSEVKTKVQSGKGALRRIRGKDKEEKVKPPKPKCRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVCCKNPHKEDYVESDEDDDLEDFEMPKDVPEPMTQSEEPVVAEPRQEENSMAPPDSSAPISLVPLNNLQQSQHPLVLVQNEKGEYQGFNIFQGSKPLDPVTVGFTIRVQLQHTDGFGSLPQYAYIMPTIDPPNPPAPSLSPPPPPAPDREVIEPPAKKFRTSRTRRGRANFSALDTVDELVSGGSRSNSAAGDRSSATDNAHSLFEEIMSGSDDL
What is the function of this protein?
The Msl proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation).  Msl-2 is required for translation and/or stability of msl-1 in males.  In complex with msl-1, acts as an E3 ubiquitin ligase that promotes ubiquitination of histone H2B.
What are the official names of this protein?
E3 ubiquitin-protein ligase msl-2, E3 ubiquitin-protein transferase msl-2, Protein male-specific lethal-2.
What is the protein family that this protein belongs to?
Belongs to the MSL2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Msl-1 and msl-2 colocalize to many sites on the male X chromosome.
Protein: Y3322_BACLD
Sequence: MLFLHDVWVNWFEGEENGYNVCHFHEWRKEDSVELLDQVPLLRVSSVLFHYIENDLSELPAELLNEVHQKAYIRKNHERTQLDHCFVVTDGIGILAVDTAGYTIPVRKSRLIPRQEQLVYEMVKDVEAETYEFAPEKLQSSKEYHILSLSPEHVRGLTRKERQLKQLLFMALDQLKGLQNRAEIAYWYTEWNPYMYEQIKRMTFEEIWDMLFNETIDGWSDKHRDFCENLIKGQPFFEKLWEIENESKVN
What are the official names of this protein?
UPF0736 protein BLi01230/BL03322.
What is the protein family that this protein belongs to?
Belongs to the UPF0736 family.
Protein: RL29_SHEB9
Sequence: MKASELREKSVEELNAELLGLLREQFNLRMQHATGQLTQTNQLKLVRRNIARVKTIITSKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RPOA_TREPA
Sequence: MPRRNLLKGFKRPKVLEFLSENSSECYGKFTASPFETGFGTTVGNCLRRVLLSSIQGYAVTGVRITSFDADGVAHFISSEFEQIPHVREDTLEILNNFKRLRFLLPQGAESSTFTYEFRGAVSLTGKDFAKKFQLEVLSQDLLIMEMMDGAHVEVELHVEFGRGYVPAESHDRYADLVGVIPVDAIFSPVLRVRYDIQSCRVGQRGDYDQLSLEVWTDGTVRPEDAIAEAAKIIKEHFTVFVNFDETALDLEDEPEEDDPAVLELLNTKIADVDFSVRARNCLLTMGIKTLGELTRISEQTLANTRNVGKKSLSEIQGKLQEYNLRLGMADYNHVGVVSRLMRQKEEIDEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: ENO_BLOPB
Sequence: MPKILNIVGREVIDSRGNPTVETEVYIKGGSRLASVPSGASVGSQEALELRDNNNNRFFGKGVTKAVSFVNGPIHKALIGMDVTQQRVIDTIMIDLDGTSNKSKFGANAILSVSLAVAKAASAFKNVPLYQHISDLYDAPKNTLVMPLPMMNIINGGKHADNNLDIQEFMIIPIGAKTIKEAIQMGSEISYNLRVILSNKGISTQLGDEGGYAPNLNSHATALELIKESIEQSGYILKEDIVLAIDCAASELFDTSTNKYNIKSEKKFFTSEEFTYYLSSLAQKYSIVSIEDGQSEYDWDGFAYQTKVLGNKIQLIGDDLFATNINLLQMGINRNIANSILIKCNQIGSLTETLETIKMAKNAGYGTIISHRSGETEDTSIADIAVGTSAGQIKTGPVRCSERVAKYNQLIRIEEMLGKKGVFYRFKNKLMS
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: URE2_METSB
Sequence: MIPGEIIVAEGDITLNADRDAITLNVANLGDRPIQVGSHYHFAETNAALSFDRAATLGRRLDIAAGTAVRFEPGQTREVALVPFAGAREVFGFSGAVMGKLDKD
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.