PharMolix/UniProtQA huggingface dataset:
Protein: KPC2_APLCA
Sequence: MSRRAKMVFNGSVKIKVCEAVDLKPTDFSLRLQKGSTKEKASQMIEPYVNIDVDEVYIAKTTTKPKSVKPQWVWNEDFTSEVHNGQNVNLTVFHDAAIPPDEFVANCTIPFDDVKGKSDFWIDLEPNGKLHVVIELCGSATEAAESTPKEKVFKEKEGMLNRRRGAMRRRVHQVNGHKFMAMFFRQPTFCSLCRDFIWGLGKQGYQCQVCTCVVHKRCHQHIVTKCPGSRDVANDEVTGKRFNINVPHRFNVHNYRRPTFCDHCGSLLYGLVRQGLQCDVCKMNIHKRCQKNVANNCGTNTRDMAQILQEMGISGDKLRPKTKKLSISESHESPNKSSPMHERSLSSPIPVIQDSDEAQPGEMGLPSDSLPVNASNEHQGSRTRSPSSDRSRSHHSRISLHDFNFIKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILALSAKHPFLTALHSSFQTKERLFFVMEYVNGGDLMFQIQRARKFDEPRARFYAAEVTLALMFLHRHGIIYRDLKLDNILLDAEGHCKIADFGMCKEGMTENKLTQTFCGTPDYIAPEILQELKYDASVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKGFMTKNPAKRLGCVTTQGCEKAILVHPFFHEKIDWEALEQRKVKPPFKPKIKNKTDANNFDRDFTSEDPVLTPVDPAVIKTINQEEFRGFSFANPDYGKLEMEASGQAH
What is the function of this protein?
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins.  PKC also serves as the receptor for phorbol esters, a class of tumor promoters (By similarity).
What are the official names of this protein?
Calcium-independent protein kinase C, APL II.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: ENO_SULAC
Sequence: MNDRFRIRKLKGYEIIDSRANRTIRVRVETYDGIVGFGDAPAGASKGANEAVELKDKNGRVIDAVELVNTVLSDSLKDYDVRRQRVIDTTLIRLDGTQNKSRIGGNTMIATSIAVLKTASRALGQEYFEYIGGPRAKYIPMPLLNILNGGLHAGNNLKIQEFIIIPKNFDKFTEAIQASIEVYKRLKDLITERYGKIYTALGDEGGFSPPLEKTMDALDLVYTSIKSLGYEDKIFMGMDAAASNFFHESHYELDGKRYTAGELIDYYKQLADMYPLMYIEDPFEENDYDSFSQLQSKLKKTIVTGDDLYVTNIEYLKKGIERMSSKGTIVKPNQIGTITETLDYIDFARRNAVKTIVSHRSGETEDSIIADLAVGTQSEFIKTGAPSRGERTSKYNRLIEIELDYGLEFYGKNFYL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MOC2B_ASPCL
Sequence: MASQPPQEPTPTATSTPSTSALASLPPHLDPTTYPRTLTSPTHNIHLELTYSPLNPSQALTHTSSPAAGANVLFLGTTRDTFEGRAVSQLSYTCYPPLALKTLLDIATKAAEKFRLEGVYIAHRLGVVPIQESSIVVAVSAGHRGMAWRAGEEVLEEVKARLEVWKREEFVDGGMEWRENRERDAEGKVVAEKQEERE
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Common component for nitrate reductase and xanthine dehydrogenase protein H, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_METSB
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRKYAGVGDIIVVSVKEAIPRGRVKKGDVMKAVVVRTAKDIKRADGSVIRFDSNAAVLINNQAEPIGTRIFGPVPRELRARNQMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: YIDD_LISMO
Sequence: MKKILIGGIRLYQKYISRFTPATCRFYPTCSAYGIEAIQTHGALKGSYLAIRRISKCHPFHKGGLDFVPPKKDKNADSEHSCKVHHHH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RECF_PECAS
Sequence: MALTRLLIKDFRNIEAADLALVPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSIQAGRVIRHDQPEFVLHGRIDGTETERAVGLSKNRQGDSKVRIDGSDGHKVAELAQLLPIQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFAAWSNMKRLQRQRNAALRQVSHYGQLRAWDQELVPLAERISEWRAQYSAAIANDIAATCTQFLPEFSLSFSFQRGWDKESEYAELLERQFERDRMLGYTALGPHKADFRIRTSGVAVEDMLSRGQLKLLMCALRLAQGEFLTRQNGLRCLYLIDDFASELDSTRRRLLAERLKATHAQVFVSAVSAEQIEDMIGEKGKMFRVEQGKITVQSQD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_BDEBA
Sequence: MAFNLLNKDIDTLTCPALVVFSKSSSQKDKLAKVTHSEIHKALLPSLEEKTISGKHQETVVFREFSFKGFRHVIVVGLGKENEITHESVRQSMASAYEAIKALNVTEAAVHFDGITAGKKDAADFAKATAEGLILTSYVFNELMSGKKETKEINVHVVSKMGNDKAVKAAFNEGAILGSVVNFSRRLGDLPGNLMTPTILADSAVEGAKGIANLKVTVWDKARIKKEKMGGLLGVSNGSDQEPRFIIMEYKGAAASKKPVCFVGKGLTFDCGGISIKPGAGMEEMKYDMCGGANVIGTLLAIAKLKLKVNAVGLVASTENLINGSATKPGDVHTARNGKTFEVNNTDAEGRLILADALSYATELQPQMIVDAATLTGAMVIALGNTHTGYFTRNSALKTKVEKAAAESGEWVWNMPLTDFHVKDMKGTYADLSNISSGKGAGSATAAAFLEQFVGEGIPWAHFDIAGTGWAVGNRLPYCPKKGASGAMIRTFVEIAKQYT
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASB8_HUMAN
Sequence: MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 8, ASB-8.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCPT2_SHEEP
Sequence: MHRPPLPLVLLLLCCRAQAGEIIGGTESKPHSRPYMAYLEIVTSQEKQVACGGFLIRRDFVLTAAHCAGRSVTVTLGAHNIQKKEDTWQRLEVIKQFPYPKYEPVGVHDIMLLKLKEKANLTLAVGTLPLPPHVTFIRPGRMCQVAGWGRTGVKEPASSTLQEVKLRLMEPRACRHFRAFDHNLQLCVGNPQSTKSAFKGDSGGPLLCAGVAQGIVSYGLSSAKPPAVFTRISPYRPWIDEVLKEN
What is the function of this protein?
Putative mast cell chymase.
What are the official names of this protein?
Mast cell protease 2, sMCP-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Secretory granules.
Protein: Y5G4_ENCCU
Sequence: MNTFSPQQHTENRLRWSPALKGLPPLVSIAFPALIYLIFGKDRFEENPFLKFITLLLPLSYSAAHHLFLVHTSWNRSNKPEGILHSISYYTLNLLLLTFATISILSIIAFPFDEWEGDDSYYCSIILPSFFMPSVYLLSTSCCLVPGRIGFTDTGINVPIGMSILLCPAVSFVLVCKESEYHLLPAILFPILILIRLFKEKCFPSEKNALPTAPWRTAIFVFILILSIFIYTLMARVFVISLYDYLSRTVFYSNTAPVLRPDRILSLL
What are the official names of this protein?
UPF0328 protein ECU05_1640/ECU11_0090.
What is the protein family that this protein belongs to?
Belongs to the UPF0328 family.
Protein: NIFW_RHILO
Sequence: MRSCFAESRAIDVTDILARLKSLSAAEEFFAVLGISYDPRVLNVSRLHILKRMGQYLAEEDFAGLPDGVIAARARATLERAYEDFATSSPLTHRVFKVLKEHDPDKPATRDHTFVPFESILRRFGTE
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: ISPF_FRAT1
Sequence: MSFRIGHGYDVHKFTSAKQNIIIGGVEIAYHLGLEAHSDGDVLIHALCDAILGALGLGDIGKHFLDTDNQFKNIDSKFFLAEIKKMLDKKQYSISNIDCTIIAQAPKMLPHIEKMRACLANILEIQISQINIKATTTERLGFIGREEGIATHVVCLLYR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RL28_RICRO
Sequence: MSRKCELTGVGVLYGNNVSHSQRKTRRRFEPNLRSVKFTSDITAGEYRLSVNARCISSVEKAGGFDAYILKADDNVLSGNARAIKKKIIQTKTAKSL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PNP_HYDS0
Sequence: MIVKAEIGNQDPIYIEANKYAHQADSSILISQGGTKVLVTVCVSEEPLCGIDFAPLSVDYRERSFAWGKIPGGFIKREGKPTDREVLISRVIDRPLRPLMPKGFLNEVVVTCLTLSADDKYDPDVLAITGASAALVSSSVPFEGPIAGMRVCRVNGEFIINPTYEQRKNSDMDIVMALSKDAIVMVEGGAKEVEESVLLDALFFGLEKGQTLIKAQEELVDSLKPEKKPIGHIGLSDDMANKLKEIASSKILEAFSIEDKKERSKALKDVYAQAMQKLGISKEQEFDFLVSFKDLESQLMREQILKYKKRIDGRKETDIRPITIEMHPLERPHGSAVFTRGQTQALATVTLAPKDEAQLVETIFEGETFKRFMLHYNFPPFSTGEARPWGPPRRREIGHGALAERALEPLLAKEEDFPYIIRVVSDILESNGSSSMATVCAGSLALFDAGVPMKKHVAGIAMGLIKDGDNFVILTDILGDEDHLGDMDFKVAGTRDGVTSVQMDIKIKGLSKDIMIKALNQAKEARMFILDKLYEAIPEPNKEVSKYAPKAQVMKIPEDKVGLVIGPAGKNIKYIKEQFGASVWIDGANAYINAPTIEAVNKAADFINSLIQEVEVGGVYEGKVIRVENYGLFVEVLPGKVGLLHASAMTEKPTINVGDTIKVKVMAIDEQNRLNLCSPDYQKPENQERPRKEQLNRKPHHRK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_CHRVO
Sequence: MAVGKEILTKIRSVQNTQKITRAMQMVSTSKMRKTQERMRAARPYAEKVRTVMAHLAQANAELGHPLLARRETIKRAGIILVSSDKGLCGGLNVNSFKRFFGKVKELQDQGIEVDVCCLGQKGLAAAQRARLNVVASAVHLGDMPKMEKLIGPLTVLFRQYAEGELDAVYIVYSSFVNTMKQEPALEQLLPLTPHHMVVEHSHSWDYLYEPDAPTLMEFLVRRYLESVVYQALAENMASEQAARMVAMKAATDNAGNTIKQLRLVYNKARQAAITTELSEIVAGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CH60_CAMFF
Sequence: MAKEIIFADDARNRLYSGVKKLNDAVKVTMGPRGRNVLIQKSFGAPSITKDGVSVAKEIELKDTIENMGAGLVREVASKTNDEAGDGTTTATVLAHAIFKEGLRNITAGANPIEVKRGMDKFVEAVTSELKSAAKKVDGKKEIAQVATISANSDSSIGDLIAEAMEKVGKDGVITVEEAKSINDELNVVEGMQFDRGYLSPYFITNAEKMQVELSSPFILLFDKKITNLKDLLPVLEQIQKTGKPLLIVAEDIEGEALATLVVNKLRGVLNISAVKAPGFGDRRKAMLEDIAILTGGEVISEELGRTLESASLQDLGQADRVVIDKDNTTIVNGAGDKDSIEARINQIKAQIAETTSDYDKEKLQERLAKLSGGVAVIKVGAATETEMKEKKDRVDDALNATKAAVEEGIVVGGGAALIKAGNRVNLSLKGDELIGAEIVKRALFAPLRQIAENAGFDAGVVANSVSCADCPNYGFNAASGEYVDMFEAGIIDPVKVERIALQNAVSVASLLLTTEATVSEIKEDKPAMPPMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_RENSM
Sequence: MLIPRRVKHRKQHHPGRSGQATGGTKVSFGEYGIQALTPAYVTNRQIESARIAMTRHIKRGGKVWINIYPDRPLTKKPAETRMGSGKGSPEWWIANVKPGRVLFELSGVNEEVAREALRLAIHKLPLKARIVRREGGE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MAK16_YEAST
Sequence: MSDEIVWQVINQSFCSHRIKAPNGQNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERIKLSKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQVMITERRLALREEERHYVGVAPKVKRREQNRERKALVAAKIEKAIEKELMDRLKSGAYGDKPLNVDEKVWKKIMGQMEEENSQDEEEDWDEEEESDDGEVEYVADDGEGEYVDVDDLEKWLADSDREASSASESESDSESESDSDSDEENKNSAKRRKKGTSAKTKRPKVEIEYEEEHEVQNAEQEVAQ
What is the function of this protein?
Its role might be as part of the apparatus concerned with the nuclear events of the cell cycle.
What are the official names of this protein?
Protein MAK16, Maintenance of killer protein 16.
What is the protein family that this protein belongs to?
Belongs to the MAK16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSRA_VIBVU
Sequence: MLNKQIMVDADNALAGRQEAMAVEPIHFVNGSDITASATQGQQEILFGMGCFWGAERLFWQLDGVVSTSVGYSGGFTLNPTYQEVCSGQTGHTEVVRVIFDPQVLPLEQLLEKFWERHDPTQGMRQGNDLGTQYRSAIYTFSDQQLDIALASQQAYQAALANQQHNTITTEIRPAGPYFYAETYHQQYLAKNPEGYCGLGGTGVCFPPA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: ALKR6_ARATH
Sequence: MAEEACQVRRMKLGSQGLEVSAQGLGCMGLSDFYGAPTPETNAVALLRHAINAGVTFLDTSDIYGPETNELLLGKALKDGLRDKVELATKFGITASEDGKFGFRGDPEYVRIACEASLKRLGVTCIDLYYQHRIDTTLPIEITIGELKKLVEEGKIKYIGLSEASASTIRRAHAVHPITAVQIEWSLWSRDVEEDIIPTCRELGIGIVAYSPLGRGFLGLPRFQQENLENNKILYEKVQAMATKKSCTPAQLALAWVHHQGDDVCPIPGTSKIQNLNQNIGALSVKLTPEEMVELEAIAQPDFVKGERYDNNMVTYKDSETPPLSSWKAR
What are the official names of this protein?
Probable aldo-keto reductase 6.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: H11_HUMAN
Sequence: MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETKPGASKVATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
What is the function of this protein?
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber.  Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers.  Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
What are the official names of this protein?
Histone H1.1, Histone H1a.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Mainly localizes in euchromatin.
Protein: RPIA_STAHJ
Sequence: MKDSKELKIMTVDDAVAQIEDNMVLGIGTGSTIELLIPKLAERIHKEQLNITGVCTSNKSAFIAKKLDINVVDINDVGHVDLAIDGADEVDVNINLIKGGGGALFREKVIDEMAHRFVVLADESKLVNYLGESFKLPVEVDKFNWFHIAKKIEAFDDIITERRMSDDVPFITDNGNYILDCQLNKQIDPYQFHEYLIHLTGVLETGYFLNITDQVIVGTQDGVKIINKSN
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: IMDH_STRPY
Sequence: MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPFFLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMTSEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRGMGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGYVGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: VPY_BIV29
Sequence: MSLLVPVRTHQRHHPVVVELFVWEGTNDPTTEWPPLTRRNIHRLWQYARTLGGDDNVATAQRKLWRKANWLAFLEHVQRT
What are the official names of this protein?
Protein Vpy.
Protein: KTHY_GEOTN
Sequence: MNGYFFSFEGPEGAGKTTMIGKLESFLRERGFDVMVTREPGGVRIAEAIRALILNREYTEMDGRTEALLYAAARRQHLLEKIVPALEAGRVVLCDRFVDSSLAYQGFARGLGVEEVWKINEFAIDGYMPSLTVYFDIDPQIGLERIRQNREREVNRLDLETLSFHDKVREGYRKLAKRFAERIVVIDASRPLDDVFSETVATVLSRLEGSKRHFHESNRDDSCWT
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ICEF1_HUMAN
Sequence: MTSYMAIDGSALVPLRQKPRRKTQGFLTMSRRRISCKDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTVERASECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECYSESEQEDPEIAAETPPPPHASQTQSLTAQQASSSSPSLSGTSYSFSSLENTVKTPSSFPSSLSKERQSLPDTVNSLSAAEDEGQPITFAVQVHSPVPSEAGIHKALENSFVTSESGFLNSLSSDDTSSLSSNHDHLTVPDKPAGSKIMDKEETKVSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRTLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQRASPAPDDTDDTPQELKKSPSSPSVENSI
What is the function of this protein?
Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner.
What are the official names of this protein?
Interactor protein for cytohesin exchange factors 1, Phosphoinositide-binding protein PIP3-E.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocated with PSCD2 to the plasma membrane upon epidermal growth factor (EGF) stimulation.
Protein: CAT1_SCHPO
Sequence: MSHSDFNMEPEYVSFSDKDTKSILNESKSSLKDVKPSLEEKSYITPGLVDDVEPKGKNFVVRFFDDFKPAKATGEDGTALKRSLKSRHMQMISIGGAIGTGLYVGSGSSLADGGPASVIINYSLIGIMMFFIVYALGEMAVAYPVAGGFNTYATRFIDPAWGFAVSWNYFINYFVTFPLELTTCAITFRYWTDINSAAWISIFLVVIIIVNLFGVRAYGEVEFILSTVKVVATFGFIILAIIINCGGVPTDHRGYIGGSIIKHKPFRHGFKGFCSVFTTAAFSFSGTEVIGLAAAEVDNPQKALPHAVKQVFWRIAIFYVVSLILIGLLISPDDPNLMGNGSTSVSPFVLAIKEANIKGLPSVFNAVIIISVVSVTNSSTYTAGRTLHGMANLKQAPSFFKYTDRLGRPLLAMIVVLLFGFFAYINEADKNGNDVSDTVFNWLLALSGLSNFFTWGSICLCHIIFRLAFKKQGHSLKELGFVSPMGIWGSCIGLFFNILCLMAQFYVSLFPIGGKPNANDFFQGYLAAPVTLAFFIGYKIYDRSHIPSLDKLDITTGLKTYENLDEEEDEPTTASKRIFKKISSVFC
What is the function of this protein?
Major permease specifically involved in arginine and lysine uptake.
What are the official names of this protein?
Cationic amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell tip. Note=enriched toward the growing ends of the cells.
Protein: COAA_ECO27
Sequence: MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTA_YERPE
Sequence: MKSQSKRTSRLFVFVGVVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTPLAPVQAATATEQEVPRYLTGLGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEIDPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTGLISQQELDTQSSLVRQSEGSVKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVFTLPESDIPAIIQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKARFNNEDDVLFPNQFVNARIKVDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTTGIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPRSANTDANPASAEKAAAEAEGSTPHQGRGRPANAPARSTTAAEKS
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PETN_COFAR
Sequence: MDIVSLAWASLMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: GUC2B_RAT
Sequence: MSGSQLWAAVLLLLVLQSAQGVYIKYHGFQVQLESVKKLNELEEKQMSDPQQQKSGLLPDVCYNPALPLDLQPVCASQEAASTFKALRTIATDECELCINVACTGC
What is the function of this protein?
Endogenous activator of intestinal guanylate cyclase.  It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.  May be a potent physiological regulator of intestinal fluid and electrolyte transport.  May be an autocrine/paracrine regulator of intestinal salt and water transport.
What are the official names of this protein?
Guanylate cyclase activator 2B.
What is the protein family that this protein belongs to?
Belongs to the guanylin family.
What are the subcellular locations of this protein?
Secreted.