PharMolix/UniProtQA huggingface dataset:
Protein: DISA_CLOB6
Sequence: MRIEKDKELMNILKIMAPGTPLREGLENILRAKTGGLLILGDSDQILKLVDGGFKINSEYSPSYVYELAKMDGSIVLSSDLKKILCANAQLIPDSSIPTFETGTRHRTADRVAKQTGAIVIAISQRRNIITVYKGGIKYVLRDSSIILARANQALQTLEKYVAVLDRVVNNLNILEFKDIATLFDVLTAIQRSEMVMRIVSEIERYICELGNEGRLIDMQLSELIKSVEEDGILLIRDYCRSNMEYEDIYKQIQGLSSEELLNLDGLSKIIGYTGVPLVDTLISPRGYRMINKIPRIPSNVIENLVANFNQLKCVMEASYEQLDNVEGIGEARAKAIKNGLRRLREQIMLDKV
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation.  The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: THTR_RAT
Sequence: MVHQVLYRALVSTKWLAESIRSGKVGPSLRVLDASWYSPGTRQARKEYQERHVPGASFFDIEECRDTTSPYEMMLPSEAHFGDYVGNLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLNRSLLKTYEQVLENLQSKRFQLVDSRAQGRYLGTQPEPDAVGLDSGHIRGSVNVPFMNFLTEDGFEKSPEELRAIFQDKKVDLSQPLIATCRKGVTACHIALAAYLCGKPDVAVYDGSWSEWFRRAPPETRVSQGKSGKA
What is the function of this protein?
Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA.  Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA (By similarity).  Involved in the formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes.  Other thiol compounds, besides cyanide, can act as sulfur ion acceptors.  Also has weak mercaptopyruvate sulfurtransferase (MST) activity.
What are the official names of this protein?
Thiosulfate sulfurtransferase, Rhodanese.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RF1_LACAC
Sequence: MDKVMAQLESLVAHYEELQEMMADPEVINDTKRYMEISKEEADLREVVQKYKKYKENKKEIEDNKEIISNETDSDLIEMAKEENAELEKEIPELEDQIKILMLPKDPNDDKDIIMEIRGAAGGDEASLFAGDLLRMYEKYAERQNWNVSMIDSEPTEVGGYKRVAIMITGDKVYSKLKYENGAHRVQRIPVTESQGRVHTSTATVAVMPEYEQVDIDIDPKDIRVDVYRSSGAGGQHINKTSSAVRMTHLPTGIVVAMQDQRSQQQNREKAMQILKSRVYDYYESQNQAQYDAKRKNAVGTGDRSERIRTYNYPQNRVTDHRIGLTLNKLDRVMNGELDEIIDALILYNQTKQLEELADNA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDC80_ASPFU
Sequence: MRSDGLRLTNIFLIQTLGSVQNYSALPQPSSALKRTSSIGYQNPPFTSQHTRSMSLLNSASRPQQPNFQRSSSGGAFGADAGLSSVRRSVSSNIFHGASVGRPSYAPGSLSASSASQSLQRRSSVFSRPSVGGPMGHQSFFTQVPNAAGVPRDPRPLRDRSFQARIGQELLEYLTHNNFELEMKHSLGQNTLRSPTQKDFNYIFQFLYHRIDPGYRFQKSMDAEVPPILKQLRYPFEKGITKSQIAAVGGQNWPTFLGMLHWLMQLAQMMDRFVLGEYDEACAEMGVDVSGDRIIFRFLTGAYHDWLQGGEDEDDETAEKRLVPHIESMAQEFERGNEKYMQEMQVLEAENRALRDQIEELEKNAPDMAKLDKHFRILEDDKRKFEDYNQNVQGKIEKYENRIKFLEEEIQKVEAELQAAEEERSSLQSSVDQQGITIQDIDRMNTERDRLQKSLEDTTARLEETHARVMEKEAEASRKLEDLEEIVKVYNTLGYQTSLIPSTAVNAKGQDYELSLNINDNSFSASQIGGLPNRISSEADRLLAEPFTGYHPAHLLNLDLRGMVRSSLQALRKEINERRKRAIDDDLERRNLLDNIKEAMDEKRSEVEALEHKRRAAEEEFERLKEITTTQKLASDAQIEKMEKELAKMRATLSESVQLMEQREMNTNIEYEQLTLRANALREELHTNVESMLNDVIRFKVHIQKGLEDYESFVVDEVEQELGGDLPATKDVTSQT
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein ndc80.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: RIMO_ECOK1
Sequence: MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWRKICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPH6_YEAST
Sequence: MKFIALISGGKDSFYNIFHCLKNNHELIALGNIYPKESEEQELDSFMFQTVGHDLIDYYSKCIGVPLFRRSILRNTSNNVELNYTATQDDEIEELFELLRTVKDKIPDLEAVSVGAILSSYQRTRVENVCSRLGLVVLSYLWQRDQAELMGEMCLMSKDVNNVENDTNSGNKFDARIIKVAAIGLNEKHLGMSLPMMQPVLQKLNQLYQVHICGEGGEFETMVLDAPFFQHGYLELIDIVKCSDGEVHNARLKVKFQPRNLSKSFLLNQLDQLPVPSIFGNNWQDLTQNLPKQQAKTGEQRFENHMSNALPQTTINKTNDKLYISNLQSRKSETVEKQSEDIFTELADILHSNQIPRNHILSASLLIRDMSNFGKINKIYNEFLDLSKYGPLPPSRACVGSKCLPEDCHVQLSVVVDVKNTGKEKINKNKGGLHVQGRSYWAPCNIGPYSQSTWLNDDANQVSFISGQIGLVPQSMEILGTPLTDQIVLALQHFDTLCETIGAQEKLLMTCYISDESVLDSVIKTWAFYCSNMNHRSDLWMDKSDDVEKCLVLVKISELPRGAVAEFGGVTCKRLIVDDNDSDKKEREENDDVSTVFQKLNLNIEGFHNTTVSAFGYNRNFITGFVDSREELELILEKTPKSAQITLYYNPKEIITFHHHIGYYPVEKLFDYRGKEHRFGLHIRS
What is the function of this protein?
Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.  Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor eEF-2 (EFT1 or EFT2) to diphthamide.
What are the official names of this protein?
Diphthine--ammonia ligase, Diphthamide synthase, Diphthamide synthetase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the Diphthine--ammonia ligase family.
Protein: RK19_NEPOL
Sequence: MTKEDKEKKEKIEYRPLPAIAVGDLVKVGLLILEGDKERVQTYEGTVISKHRAGLNSTITVRKTFQGVGIERVFCLYSPRMVFVEFIRHSKARRAKLYYLRNRVGKQSRLEERFDLVTNTILLDLLASESDPSNSRT
What are the official names of this protein?
50S ribosomal protein L19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YL575_MIMIV
Sequence: MDPSILSKLEYKTVNNIYYGTGIFIIRDDNDDIKYFKTYGKLTEFKHDSFLLVDLNVMIYDTVKTDYLITISDRQELTLCSASITDLKNFRIKGSRDTTNNSVLFSQFTKNNPLIVKSKNNPIYLEIKFQCETRLLKSLYFFSTGPKCGIKKVDENNYTNEYTHFDNFTEIYQTDEKKHEIVTFNNWYKFDDFIGFKLYNLNFSIINNNMEIIDIEHDRVSLSLNEFVNNFDFELLTEDNPIFIESGNIPSVLFFDKCTDSEYHRINFTVKKIDEID
What are the official names of this protein?
Uncharacterized protein L575.
Protein: FTSP_ECOLI
Sequence: MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRRGQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMTVAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGMWLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQSPYVEVSRGWVRLRLLNASNSRRYQLQMNDGRPLHVISGDQGFLPAPVSVKQLSLAPGERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTDSLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADEPQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNSQTLEMADRGSIGQLLVNPVP
What is the function of this protein?
Cell division protein that is required for growth during stress conditions.  May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
What are the official names of this protein?
Cell division protein FtsP.
What is the protein family that this protein belongs to?
Belongs to the FtsP family.
What are the subcellular locations of this protein?
Periplasm. Note=Localizes to the division septum. Localization requires FtsZ, FtsQ, FtsL and FtsN.
Protein: AUR23_RANAE
Sequence: MAFLKKSLFLVLFLGLVSLSICEKEKRQNGEDEDENEAANHEEGSEEKRGLFDIVKKVVGAIGSLGKRNDVE
What is the function of this protein?
Amphipathic alpha-helical antimicrobial peptide with weak to moderate activity against Gram-positive bacteria, and no activity against Gram-negative bacteria (PubMed:10951191, PubMed:17259271).  Probably acts by disturbing membrane functions with its amphipathic structure (PubMed:10951191).  Strongly inhibits the formation of NO by neuronal nitric oxide synthase (nNOS) at micromolar concentrations (PubMed:11784303).  Acts by a non-competitive mechanism, probably by binding to calcium/calmodulin and as a consequence blocking calmodulin attachment to nNOS (By similarity).
What are the official names of this protein?
Aurein-2.3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Aurein subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: CEPR1_ARATH
Sequence: MRLKNFPFFVLFFFFCFNSNQSWGLMSSNQQPQFFKLMKNSLFGDALSTWNVYDVGTNYCNFTGVRCDGQGLVTDLDLSGLSLSGIFPDGVCSYFPNLRVLRLSHNHLNKSSSFLNTIPNCSLLRDLNMSSVYLKGTLPDFSQMKSLRVIDMSWNHFTGSFPLSIFNLTDLEYLNFNENPELDLWTLPDSVSKLTKLTHMLLMTCMLHGNIPRSIGNLTSLVDLELSGNFLSGEIPKEIGNLSNLRQLELYYNYHLTGSIPEEIGNLKNLTDIDISVSRLTGSIPDSICSLPNLRVLQLYNNSLTGEIPKSLGNSKTLKILSLYDNYLTGELPPNLGSSSPMIALDVSENRLSGPLPAHVCKSGKLLYFLVLQNRFTGSIPETYGSCKTLIRFRVASNRLVGTIPQGVMSLPHVSIIDLAYNSLSGPIPNAIGNAWNLSELFMQSNRISGVIPHELSHSTNLVKLDLSNNQLSGPIPSEVGRLRKLNLLVLQGNHLDSSIPDSLSNLKSLNVLDLSSNLLTGRIPENLSELLPTSINFSSNRLSGPIPVSLIRGGLVESFSDNPNLCIPPTAGSSDLKFPMCQEPHGKKKLSSIWAILVSVFILVLGVIMFYLRQRMSKNRAVIEQDETLASSFFSYDVKSFHRISFDQREILESLVDKNIVGHGGSGTVYRVELKSGEVVAVKKLWSQSNKDSASEDKMHLNKELKTEVETLGSIRHKNIVKLFSYFSSLDCSLLVYEYMPNGNLWDALHKGFVHLEWRTRHQIAVGVAQGLAYLHHDLSPPIIHRDIKSTNILLDVNYQPKVADFGIAKVLQARGKDSTTTVMAGTYGYLAPEYAYSSKATIKCDVYSFGVVLMELITGKKPVDSCFGENKNIVNWVSTKIDTKEGLIETLDKRLSESSKADMINALRVAIRCTSRTPTIRPTMNEVVQLLIDATPQGGPDMTSKPTTKIKDSIVSDHLTQTRL
What is the function of this protein?
Receptor kinase involved in the perception of C-terminally encoded plant signaling peptide (CEP) and subsequent regulation of root and shoot development (PubMed:25324386).  Required for xylem and phloem cell files morphology and organization, probably by preventing ectopic lignification in phloem cells (PubMed:21853254).  Together with CEPR2, mediates systemic nitrogen (N)-demand signaling upon the perception of root-derived peptides (e. g.  CEP1) via the up-regulation of genes involved in N uptake and assimilation pathways (PubMed:25324386).  Regulates positively lateral root initiation and development; probably repressed by the signaling peptide CEP5 (PubMed:27296247).
What are the official names of this protein?
Receptor protein-tyrosine kinase CEPR1, Protein C-TERMINALLY ENCODED PEPTIDE RECEPTOR 1, Protein XYLEM INTERMIXED WITH PHLOEM 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ETA2_SCHPO
Sequence: MMLAIDMTINENQGTRSNLESPTLSCSSKGAMQERDVMFTDHNTFNITNNKSRPGSLMKSMKRKDVYEFDEDNEFEFEMGSLIHKPSRAHSLGGTSEPVSDDHKDCMEATRQLLENSPLSSVVVKTCSDHASKRKIARSSSDDSESKVESTNSFNAKKRKDAWTEEHEKWFQARIDELLTIRSISREQMIEILEDEHAGSRLQGFLESVASFLNRKENSLLKYMRAFFQVAGYEKIDIGSLAAEEDSQLNFSLEDAQVIQKVVLSYCNNEGVDLQEFGFRMSSSSLRHTNINFLYNELRELLPTSISRKGIIRYLKEIYKPLDPKDRNAWEESELKKLYTLVEQEGTRWNSIANKLGTSPAACMSQWRFVVGTSTQETIDRRKLWTNEEEAKLLDLVKSSYRSSFHTKKMTSLFTHNNHTTSNIQREIPASDSIAWHSISKKLGTKSPESCRKQYEKTIASYSSNQRQEEDQGKKRKKRKKKKSKGKRKFYVADSLKLLEHVQRQCGEAISINAIDWKGIVKQMPKWSEEELRAQATNLVASVRGWKKTRLSESVRIAITDLKSLPPDV
What are the official names of this protein?
DNA-binding protein eta2.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPP_ALKMQ
Sequence: MSKVFVIDHPLIQHKLTLIRDKNTGSKDFRDLVKEISLLMGYEVTRNLSLQEIEIETPVGVTKSKVISGRKLGIVPILRAGLGMVDGILQLIPAAKVGHVGLYRDPETLEPVEYYCKLPVDVQEREIIVLDPMLATGGSANATLKAIKDRGVANMKLVCIVSCPEGIAAVQKAHPDVDIYVAAIDEKLNDHAYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: SP5G_MACCJ
Sequence: MKVTDVRMRKLVTDSRMKALASITLDEAFVIHDLRVIDGNNGLFVAMPSKRTSDGEFRDIAHPINSEMRQEIQEAVMKVYDETEAVEPGTIATSEVSSQLEESDSDKTLSEDLKA
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: SYFA_MOUSE
Sequence: MADNPVLELLLRRLEVADGGLDSAELATQLGVEHQAVVGAVKSLQALGEVIEAELRSTKCWELTTEGEEIAREGSHEARVFRSIPLEGLVQSELMHLPSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSIEDEVQKRLQLVQAGQAEKLAEKERNELRKRKLLTEVILKTYWVSKGKAFSTSVSKQEAELSPEMISSGSWRDRPFKPYNFSARGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMGYVQRVKRTHSQGGYGSQGYKYTWKLEEARKNLLRTHTTAASARALYQLAQKKPFTPAKYFSIDRVFRNETLDATHLAEFHQIEGVIADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPVCRLDIEPRSSKTQEAA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MON1_ASPFU
Sequence: MNPNALEQPQVAPGDDGAGGNNYGTQENSAKEPSKTGSDDSSARLEERPPPLPPRPNTLSLLDEGFISPRSTRQSSSSSLQAKATTAVSIPDISLLQLNDGGKENHPTRGPFGSLRAKASLTQLTASKGSDAGDSASIRSTAPNTELGEAENVFSDFLAQESGDVQQDSSGLLQFPEFRTDDVEDDFTSEFEPIGELDDDGRNEELLLERWKSKRKHYLILSAAGKPIWTRHGDGGLISGYIGVILTIISFYEDANDRLTSFCAGDTKFVIVTKGPLYLVAISRLLESDTQLKLQLEALYMQILSTLTLPSLTHLFSVRPSTDLKRPLQGSETLLSTLADSFTKGSPSTFLSALECLKIRKSHRQAINNALLKTKVSSLLYGLVVAGGRLVSVVRPKKHSLHPGDLQLLFNMIFEAEGIKAGGGESWIPVCLPGFNSSGYLYMYVSFLDLRENSGTSASETTTEQSVAIILISPNKEGFFEMQEMRNSLVEQLEKNNSINIIKEAIDGGRPTTTDIVPGTVLHHFLYKSRANVQFTMSSYEPEFTSISRRRSIHAKHAHVKVHHCISQSASSFAWVTPIFELYCVASPNANRNALAQSASKVVQWVQREEERLFIIGGAVF
What is the function of this protein?
Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
What are the official names of this protein?
Vacuolar fusion protein mon1.
What is the protein family that this protein belongs to?
Belongs to the MON1/SAND family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: SYH_ACIBT
Sequence: MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQKGRYRQFHQFGVETFGVATPDIEAEVILMTARLWKRMGVAHMVQLELNTLGEKEERTEYRNALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLYDFLKEDSLSHFQQLQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCGGGRYDGLVGQLKGKADQSVPAVGFGMGMERLLLLIEQVEQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAANSNIRIKTGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAIKELATAEQSQVALAELVPFLIEKFTK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MODA_BPT4
Sequence: MKYSVMQLKDFKIKSMDASVRASIREELLSEGFNLSEIELLIHCITNKPDDHSWLNEIIKSRLVPNDKPLWRGVPAETKQVLNQGIDIITFDKVVSASYDKNIALHFASGLEYNTQVIFEFKAPMVFNFQEYAIKALRCKEYNPNFKFPDSHRYRNMELVSDEQEVMIPAGSVFRIADRYEYKKCSTYTIYTLDFEGFNL
What is the function of this protein?
ADP-ribosyltransferase that efficiently ADP-ribosylates both alpha subunits of host RNA polymerase RPOA (PubMed:15489438, PubMed:10634320).  The ModA-induced ADP-ribosylation of RPOA alpha subunits inhibits transcription from viral early promoters (PubMed:7031602).
What are the official names of this protein?
NAD--protein ADP-ribosyltransferase modA, RNA polymerase ADP-ribosylase modA.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae NAD--protein ADP-ribosyltransferase modA family.
What are the subcellular locations of this protein?
Virion. Note=This protein is injected from the virion into the bacterial cell.
Protein: METK5_BRAJU
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRSIGFISDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKRPEDIGAGDQGHMFGYATDETPELMPLSHVLATKIGAKLTEVRKNGTCRWLRPDGKTQVTVEYYNDNGAMVPVRVHTVLISTQHDETVTNDEIARDLKEHVIKPIIPEKYLDDKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARRALVQVSYAIGVPEPLSVFVDTYGTGLIPDKEILKIVKESFDFRPGMMTINLDLKRGGNGRFLKTAAYGHFGRDDPDFTWEVVKPLKWDKPQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 5, AdoMet synthase 5, Methionine adenosyltransferase 5, MAT 5.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_NEIEL
Sequence: DQGAGVTYLEPSGSQIGHKESIKDTARVLGRMFDGIEYRGYGQEVVEELARYAGVPVFNGLTDEFHPTQILADLLTMREHSGKPLQQTAYTYVGDARYNMGNSLLLIGALLGMDTRIGAPKALWPSENIIAQAHSLAEKSGARLLLTEDPQEAVRGTDFIHTDVWVSMGEPKEVWHERIDLLRGYRVTADLMAAAGNPQVKFMHCLPAFHNRETKVGEWIYKTFGLDGVEVT
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_WOLSU
Sequence: MFDLFPIHGGVCAPEGFSADGIAAGLKKEGKLDVAFVHSLFPAKVSALFTTNRFAAAPIRYFQGLGEVFDCNFVLINAKNANAMTGAEGIEDIEWLMERLKHRFPSLVNPVMSSTGVIGARLPKEKIEASLGEIVLGKKEGARAAQAIMTTDAFSKEVAFKVELPDGRSFCIGAMAKGAGMIDPAMATMLCFITTDADVPENRMKELLQKAVHTTFNAISVDGDTSTNDTVMLFSNKASGVYEEEAFLMALERVMHKLATDVARDGEGAKKLVAFEVSGAASEEEAIKAAKALTTSLLVKTAIFGEDPNWGRIASTIGSSGVECDENRLRISFGEVLVYDRGAILFDKTIEEKAASVMRQESFKIHCDLGIGRGKFTAYGCDLGYEYVKINADYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IKBP1_XENLA
Sequence: MAATSPVSRIFASLQPANSSALHTGDLENRAGIVVGQHGGREVQVSGSAELSAAPDRAQVCIAVSSSKGTAAEAKSSVQRRLEYIAQSLRQGGVTEENITVSKEFQRLSNTYKMEAVVCVVFSDFDKLQSNCNLLVEKLDSSVNISPPHFYHTADCLEKLRREVCLGAVANARRKAQEVCRLVGHSLGKALIIREEELREWEDQAESSQAHQSIQSKIKTATIYAASKILATFEIKGKERHKKNR
What is the function of this protein?
May be part of a signaling pathway that leads to NF-kappa-B activation.
What are the official names of this protein?
Interleukin-1 receptor-associated kinase 1-binding protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the IRAK1BP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLMM_VESOH
Sequence: MDNYFGTDGIRGKVGIEPITADFFLKLGWSVGSVLAQQGKASVIIGKDTRISGYLFESALEAGFLSAGVDVGLLGPMPTPAVAYLTQTYNANAGVVISASHNHFQDNGVKFFSAKGLKFSSQDQSAIENKLTKPMINVGADKIGKAYRHEQPLGRYIEFCKSTFDRTQSLLGLNIIIDCANGATYHIARSVFSELGANIHIINNTPDGFNINERCGATNTKHLQQVVLELKADLGIAFDGDGDRLIMVDENGELVDGDELIFIIAKAWQSQGRLVNNTVVGTKMSNLGMRYALRDLNIQFIEVNVGDRFVMEQMQKSGSILGGEGSGHIICLNKTTSGDGMISALQVLEVLVKSQSSLTQLKQSMNKYTQILINIKIQTQVNLENHTKLQQAQLEVEKMLGSEGRVVIRASGTESLIRIMVEAKNKIIAKKGAKKLSNVFK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RNZ_CROS5
Sequence: MEITFLGTSSGVPTRSRNVSSVALRLPQRAEVWLFDCGEGTQHQLLRSDVKISQITRIFVTHMHGDHIYGLTGLLASCGLAGSGQPIEIYGPPELKDYLKACAKYSHFKLPHHIRFHPIHPGILYEDAEFSVSCNLLKHRIPAYGYRIAESDRPGRFNVEKAKSLGIPPGPVYGELKQGKTVTLPDGRNIRGQDLCGERETGRKVIYCTDTVFCEGAIALSEDADVLIHEATFAHQDAQLAFDRLHSTSTMAAQVALAAQVKQLIMTHFSPRYAPGNALQLDDLLQEARAIFPNTILARDFMTYEVPRRSSD
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: YJGA_ECO8A
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: EFTS_CELJU
Sequence: MSAVTPALVKELRDRTGLGMMECKKALGDANGDIELAIENLRKVSGLKAAKKEGRTAADGVVAVKVAADNSYGVAVEVNSETDFVARDAGFLAFVNSVVEKAFAAKQTDVAAVMAGELEIAREALVQKIGEKISVRRINLVEGGVVGGYVHLNNRIAVLVQLEGGSEDVAKDVAMHVAAVNPQVVSADQMPADVVEKEKEIIRAQPDMAGKPAEIVEKMIVGRISKFLKEASLVDQPFVKNPEQTVAQFAKAGGATVKSFVRLEVGEGIEVAVVDFAAEVAAQVAASAKS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_MYCPA
Sequence: MTLDPQIAARLKRNADGLVTAVVQERGSKDVLMVAWMDDAALARTLETREATYYSRSRGQQWVKGETSGHTQYVHSVRLDCDGDTVLLTVDQVGGACHTGDHSCFDADVLLHPQD
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_CAMHC
Sequence: MSKDDVIEIDGNVIEALPNATFKVELDNKHVILCHIAGKMRMHYIKIMPGDRVKVELTPYSLDKGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.