PharMolix/UniProtQA huggingface dataset:
Protein: OTX5A_XENLA
Sequence: MMSYIKQPHYAVNGLTLAGTGMDLLHSAVGYPTTPRKQRRERTTFTRAQLDILESLFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQSTGQAKPRPAKKKTSPARETNSEASTNGQYSPPPPGTAVTPSSTAGATVSIWSPASISPIPDPLSIATTPCMQRSAGYPMTYSQAPAYTQSYGGSSSYFTGLDCGSYLSPMHPQLSAPGSTLSPIASSTMGSHLSQSPASLSAQGYGASSLGFTSVDCLDYKDQTASWKLNFNATDCLDYKDQSSWKFQVL
What is the function of this protein?
Transcription factor involved in anterior and eye development.  Promotes the differentiation of both rod and cone photoreceptors cells in the retina.  Together with other retinal homeobox proteins, acts as an effector of a cellular clock which, depending on cell cycle progression, establishes the generation of distinct retinal neuronal cell types.  Acts synergistically with nrl to activate the rhodopsin promoter (By similarity).  Promotes the formation of anterior regions and represses the formation of posterior structures during development.
What are the official names of this protein?
Homeobox protein otx5-A, Orthodenticle homolog 5-A, Xotx5.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3511_ACISJ
Sequence: MLHYAVVFLVIALVAALFGFGGIAAGAVGIAKILFFVFVIMAVVTFVLSLLKRG
What are the official names of this protein?
UPF0391 membrane protein Ajs_3511.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CS12F_ACIS4
Sequence: MIKVYRYEIVKPLDLDWKEFGTILRQLQQETRFALNKATQLAWEWMGFSSDYKDNHGEYPKSKDILGYTNVHGYAYHTIKTKAYRLNSGNLSQTIKRATDRFKAYQKEILRGDMSIPSYKRDIPLDLIKENISVNRMNHGDYIASLSLLSNPAKQEMNVKRKISVIIIVRGAGKTIMDRILSGEYQVSASQIIHDDRKNKWYLNISYDFEPQTRVLDLNKIMGIDLGVAVAVYMAFQHTPARYKLEGGEIENFRRQVESRRISMLRQGKYAGGARGGHGRDKRIKPIEQLRDKIANFRDTTNHRYSRYIVDMAIKEGCGTIQMEDLTNIRDIGSRFLQNWTYYDLQQKIIYKAEEAGIKVIKIDPQYTSQRCSECGNIDSGNRIGQAIFKCRACGYEANADYNAARNIAIPNIDKIIAESIK
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids (Probable).  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), which requires a trans-encoded small RNA (tracrRNA), but not this protein (By similarity).  Recognizes a short motif in the CRISPR repeat sequences (the 5' PAM or protospacer adjacent motif, YTT in this organism) to help distinguish self versus nonself, as targets within the CRISPR locus do not have PAMs.  Has dsDNA endonuclease activity upon expression in E. coli of this protein, a mini CRISPR array and the probable tracrRNA.  Plasmid cleavage is centered around positions 19-24 base pairs 3' of PAM.  The mini system protects E. coli against transformation by foreign plasmids (PubMed:32246713).
What are the official names of this protein?
CRISPR-associated endodeoxyribonuclease Cas12f1, AsCas12f1, CRISPR-associated endonuclease C2c10.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas12f family.
Protein: RK1_TRICV
Sequence: MRKLSRRQKENRAKTKDSIYSNLEDAITILQETATAKFTETVELHANLNIDPKYADQQLRTTVTLPHGIGKTINIAVLTNDSNFTEAREAGADRVGSDDLIEEISQGNISFDLLIATPDMMPKLAKLGRVLGPKGLMPSPKSGTVSTTLTATLSEFKKGKFEYKADKAGVVHVSFGKSNFTHSQLMENLTALYKSIEQNRPSGVKGKYFKSLFICTTMGPSIQLDLNIFL
What is the function of this protein?
Binds directly to 23S rRNA.  Might be involved in E site tRNA release (Potential).
What are the official names of this protein?
50S ribosomal protein L1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PCNA_BOMMO
Sequence: MFEARLLRSSILKKVLEAIKDLLTQATFDCDDNGIQLQAMDNSHVSLVSLTLRADGFDKYRCDRNISMGMNLGSMSKILIFAGDKDTATIKAQDNADNVTFVFESPNQEKVSDYEMKLMNLDLEHLGIPETEYSCTIRMPSSEFARICRDLSQFGESMVISCTKEGVKFSATGDIGSANVKLAQTASIDKEEEAVVIEMEEPVTLTFACQYLNYFTKATSLSPQVQLSMSADVPLVVEYRIPDIGHIRYYLAPKIEEEDS
What is the function of this protein?
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
What are the official names of this protein?
Proliferating cell nuclear antigen, PCNA, Cyclin.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNME_SYNY3
Sequence: MQLEDTIAAIATAIVPQQGSIGVVRLSGPQSLTIAKTLFDAPGNQTWESHRILYGHVRHPQTKAAIDEALLLLMLAPRSYTKEDVVEFQCHGGIMPVQQVLQLCLQQGARLAQPGEFSFRAFLNGRLDLTQAESISELVGAQSPQAAAIALAGLQGKLAQPIRDLRNTCLDILAEVEARIDFEDDLPPLDEDSIRQQLQNLYQQLEDILNTAQRGELLRTGLKVAIVGQPNVGKSSLLNAWSRTDRAIVTDLPGTTRDVVESQLVVEGIPIQVLDTAGIRETADQVEQIGVERSRKAAQQADLVLLTVDAHQGWTEADQLIYEQVKDRPLILVINKIDLGRADLVSYPPEITNTVLTAAAANLGIEALENAIIEQVNQTNLSPQNLDFAINQRQEAVLTEAQLALKQLQQTMAEQLPLDFWTIDLRLAINALGQVTGETVTESVLDRIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_BURO1
Sequence: MTDKLIIFDTTLRDGEQSPGASMTKEEKIRIAKHLERMKVDVIEAGFAASSNGDFDAIHTIAGLVKDSTICSLARANDKDIQRAADALKPANSARIHTFIATSPLHMEKKLRMTPDQVFEQARLAVRFARKFTDNVEFSPEDGSRSDLDFLCRVLEAVIAEGATTINIADTVGYGVPELYGNLVKTLRERIPNSDKAIFSVHCHNDLGMAVANSLAGVKIGGARQIECTINGLGERAGNTSLEEIVMAVKTRKDYFGLDVGIDTTQIVPTSKLVSQITGFVVQPNKAVVGANAFAHASGIHQDGVLKARDTYEIMRAEDVGWTANKIVLGKLSGRNAFKQRLQELGVSLDSEAELNAAFMRFKDLADRKAEIFDEDIIAIVSEESALAQEQEHFKFVSLSQRSETGEQPQAKVVFAVEGKEVTGEARGNGPVDATFNAIEGEVGSGSELLLYSVNAITTGTQAQGEVTVRLSKSGRIVNGVGTDPDIVAASAKAYISALNKLHSKDDKLNPQRA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: SPEE_MYCTU
Sequence: MTSTRQAGEATEASVRWRAVLLAAVAACAACGLVYELALLTLAASLNGGGIVATSLIVAGYIAALGAGALLIKPLLAHAAIAFIAVEAVLGIIGGLSAAALYAAFAFLDELDGSTLVLAVGTALIGGLVGAEVPLLMTLLQRGRVAGAADAGRTLANLNAADYLGALVGGLAWPFLLLPQLGMIRGAAVTGIVNLAAAGVVSIFLLRHVVSGRQLVTALCALAAALGLIATLLVHSHDIETTGRQQLYADPIIAYRHSAYQEIVVTRRGDDLRLYLDGGLQFCTRDEYRYTESLVYPAVSDGARSVLVLGGGDGLAARELLRQPGIEQIVQVELDPAVIELARTTLRDVNAGSLDNPRVHVVIDDAMSWLRGAAVPPAGFDAVIVDLRDPDTPVLGRLYSTEFYALAARALAPGGLMVVQAGSPYSTPTAFWRIISTIRSAGYAVTPYHVHVPTFGDWGFALARLTDIAPTPAVPSTAPALRFLDQQVLEAATVFSGDIRPRTLDPSTLDNPHIVEDMRHGWD
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HCAE_ECOLI
Sequence: MTTPSDLNIYQLIDTQNGRVTPRIYTDPDIYQLELERIFGRCWLFLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLNQCRHRAMRVSYADCGNTRAFTCPYHGWSYGINGELIDVPLEPRAYPQGLCKSHWGLNEVPCVESYKGLIFGNWDTSAPGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNWKFPAEQFASDQYHALFSHASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGHGSGFFFTEKPDANVWVDGAVSSYYRETYAEAEQRLGEVRALRLAGHNNIFPTLSWLNGTATLRVWHPRGPDQVEVWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENWCEIQKLLKGHRARNSKLCLEMGLGQEKRRDDGIPGITNYIFSETAARGMYQRWADLLSSESWQEVLDKTAAYQQEVMK
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase.  Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: TTYH2_MOUSE
Sequence: MPAARVEYIAPWWVVWLHSVPHLGLRLQRVDSTFSPGDETYQESLLFLGVLAAIGLGLNLIFLTVYLVCTCCCRRDHTVQTKQQESCCVTWTAVVAGLLCCAAVGVGFYGNSETNDGMHQLIYSLDNANHTFSGMDELVSANTQRMKVDLEQHLARLSEIIAARGDYIQTLKFMQQMAGNVVSQLSGLPVWREVTTQLTKLSHQTAYVEYYRWLSYLLLFILDLVICLVTCLGLARRSKCLLASMLCCGILTLILSWASLAADAAAAVGTSDFCMAPDIYILNNTGSQINSEVTRYYLHCSQSLISPFQQSLTTFQRSLTTMQIQVGGLLQFAVPLFPTAEKDLLGIQLLLNNSEISLHQLTAMLDCRGLHKDYLDALTGICYDGIEGLLFLGLFSLLAALAFSTLTCAGPRAWKYFINRDRDYDDIDDDDPFNPQARRIAAHNPTRGQLHSFCSYSSGLGSQCSLQPPSQTISNAPVSEYMNQAILFGGNPRYENVPLIGRGSPPPTYSPSMRPTYMSVADEHLRHYEFPS
What is the function of this protein?
Probable large-conductance Ca(2+)-activated chloride channel.  May play a role in Ca(2+) signal transduction.  May be involved in cell proliferation and cell aggregation (By similarity).
What are the official names of this protein?
Protein tweety homolog 2, mTTY2.
What is the protein family that this protein belongs to?
Belongs to the tweety family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPH1_BURPS
Sequence: MSSTDTLSGQVAAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGAPIYVRHEIVHNKYVVEDLKKKGAIFVEELEEVPSGNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVEVAKMRQEGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVEDVRRLELPDPERVALVTQTTLSVDDAAEIIGALKAKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSSRLREVAEKRGVAAYMVDAPEQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVTNVRALEGIEENVSFPLPRGLNLSSAA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1, HMBPP reductase 1.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: TSAD_MYCSK
Sequence: MIILAIESSCDETGVGIAELSEDGTVTLLADEVASSVDEHARFGGVVPEIASRAHLEALGPTMRRALDTAGVGRPDVVAATIGPGLAGALLVGVAAAKAYSAAWQVPFYGVNHLGGHLAADVYDHGPLPESVGLLVSGGHTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYPGGKVLDDLARQGDREAIVFPRGMTGPRDDPFAFSFSGLKTAVARYVESHPEASQADVAAGFQEAVADVLTRKAVRAAETLGVSTLLIAGGVAANSRLRELAEQRCAESGLTLRIPRPRLCTDNGAMIASFAAHLIAAGAPPSPLEAASDPGLPVVRSQVA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOD_HELPJ
Sequence: MKKKANEEKAPKRAKQEAKTEATQENKAKESNKENKNNKAKEGKIKEAKTKESKVKETAKEPIPVKKLSFNEALEELFANSLSDCVSYESIIQISAKVPTLAQIKKIKELCQKYQKKLVSSSEYAKKLNAIDKIKNTEEKQKVLDEELEDGYDFLKEKDFLEWSRSDSPVRMYLREMGDIKLLSKDEEIELSKQIRLGEDIILDAICSVPYLIDFIYAYKDALINRERRVKELFRSFDDDDENSVSDPKKDDDSEEDEENEERKKVVSEKDKKRVEKVQESFKALDKAKKEWLKALEAPIDEKEDELVRSLTLAYKRQTLKDRLYDLEPTSKLINELVKTMETTLKSGDGFEKELKRLEYKLPLFNDTLIANHKKILANITNMTKEDIIAQVPEATMVSVYMDLKKLFLTKEASEEGFDLAPNKLKEILEQIKRGKLISDRAKNKMAKSNLRLVVSIAKRFTSRGLPFLDLIQEGNIGLMKAVDKFEHEKGFKFSTYATWWIKQAISRAIADQARTIRIPIHMIDTINRINKVMRKHIQETGKEPDLEVVAEEVGLSLDKVKNVIKVTKEPISLETPVGNDDDGKFGDFVEDKNIVSSIDHIMREDLKAQIESVLDQLNEREKAVIRMRFGLLDDESDRTLEEIGKELNVTRERVRQIESSAIKKLRSPQYGRILRNYLRI
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor RpoD, Sigma-70.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_TROWT
Sequence: MRPVLVVDFGSQYSQLVVRAIRECGYYAEFASPSISAAECLALSPIAIFLSGGPASAYKDNAPKLDEEILNCGIPVFGICYGFQLLAQAFGGSVKKANAPEYGPADITIVNKAFFSGQPDRQTVWMSHGDSVIRAPKNFCILSTSQDAVLSFCNRDRTIAGVQWHPEVKHSRFGKHTIKAFLSSFAAPNWDPEQTICGTVDSIRKTVGCKRVLCALSGGVDSVVAATLTHRAIGDRLRCVFVDHGLLRLNEREQVEEYCSSLGLNVSTYDASDCFLSALSGIRDSEQKRKVIGREFIACFSKLQERFDIKPHFLLQGTLYPDLVESGATPGGATIKSHHNVGGLSDNLGFELLEPLKYLFKDEVRKIGLQLGIPKHIVHRQPFPGPGLAIRIIGEVTNKKLSILRAADAIVRHELRDWTDIWQCPVILLSDVQSVGVRGDSRSCGFPIVIRPVSSDDAMTADWYRLPYDVLARISGRITNEIPEIVRVVLDITPKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: WAKLF_ARATH
Sequence: MKKTKTYQVFCIAALSVLTLQLINGSSAATPPPPNSNSSTSCNRACGGVSIPFPFGIGKDCYLNGWYEVICNTSTSGSSGTTVPFLSRINSEVVNISLPDGKKLYGVVHIKGPVTSLGCSSSSSSSQVSEMSLPNLNVTGRGSPYFLTDENCLVMVGCGTKALMKDIESEILGCESSCEDSKSSEEVTNSKCDGYKCCQARIPLERPQVIGINIENTSATRGKEGCSVAFLTNKRYAPMNVTEPEQFHAGGYAVVELGWYFDTSDSRYRNPLGCRNMTRYSSYSSFDKCSCEYDYFSGMSYRICYCNYGYTGNPYLRHGCIDIDECEGHHNCGEGTCVNMPGTHSCEPKITKPEKASVLQGVLISLGVLLFVLGILGLYKFIKKRTRIIRNKNFFKRNGGLLLKQQLITKNGNVDMSRIFSSKELKKATDNFSMNRVLGQGGQGTVYKGMLAEGRIVAVKRSKVVGEGKMEEFINEVVLLSQINHRNIVKLLGCCLETEVPVLVYEYIPNGDLFKRLHEKSESNDYTMTWEVRLRIAIEIAGALSYMHSAASIPIYHRDIKTTNILLDEKYRAKVSDFGTSRSITIAQTHLTTLVAGTFGYMDPEYFLSSQYTDKSDVYSFGVVLVELITGEKPLSRKRIGN
What is the function of this protein?
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.
What are the official names of this protein?
Wall-associated receptor kinase-like 6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein.
Protein: UGTP_BACC0
Sequence: MIKNPKVLILTAHYGNGHVQVAKTLEQTFRQKGIKDVIVCDLFGESHPVITDITKYLYLKSYTIGKELYRLFYYGVEKIYDKKIASWYANFGRKRLKLLLQAEKPDIVINTFPIIAVPELKKQTGISIPVYNVLTDFCVHKIWIHREVDRYFVATDHVKKVMVDIGVPAEQIVETGIPIRSSFELKINPDIIYNKYQLCKNKKILLIVAGAHGVLGSVKELCQSFMSVPDLQVVVVCGKNEALKQDLVGVQETNPDALKVFGYVENIDELFRVTSCMITKPGGITLSEAAALQVPVILYKPVPGQENENAMYFERKGAAVVIRDDSEVFAKTEALLQDDMKLLQMKEAMKSIYRPEPADHIVDTILAENHVEPNHIPIKSPALAQSFT
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Beta-triglucosyldiacylglycerol synthase, TGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: VDAC2_MOUSE
Sequence: MAECCVPVCPRPMCIPPPYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV (By similarity).  The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).  Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol (By similarity).  Binding of ceramide promotes the Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway (By similarity).
What are the official names of this protein?
Voltage-dependent anion-selective channel protein 2, VDAC-2, mVDAC2, Outer mitochondrial membrane protein porin 2, Voltage-dependent anion-selective channel protein 6, VDAC-6, mVDAC6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Membrane. Note=May localize to non-mitochondrial membranes.
Protein: NUOC_LEGPL
Sequence: MTKNEYLIEKLQVDLANHITELTSAYGEVTIECEVQNLLPVMIELRDREEFSFDELIDLCGVDYLHYGDYDWETESATEHGFSRGVERQEAKAYAVNKPRFAVVYHLLSTKKNHRLRVKLFVEESHLIVPSVHHLWKSANWFEREAYDLYGILFDGHPDLRRLLTDYGFIGHPFRKDFPLSGEVEMRYDAKLQKVIYAPVDIVPRIVVPKVIRNDNRYIGNEGSKND
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RFA1_DANRE
Sequence: MTVRLSEGAIESLSKGTEVNNPILQCVNIRKIDGGNGVSRFRVMMSDGLHTMSSFMLSTQLNPMAEQNQLATNCVCVLKRSVTNVLKDGRRVVVILDIEVLKSADQMPGKIGDPTPYVEGQSKAPSTAPAPTARPLQPQNGSDGSTYRPSAQSFGKKPMAAPNTPGGSSKVVPIASLNPYQSKWTIRARVTNKSAIRTWSNSRGDGKLFSMELVDESGEIRATGFNNEVDKFFSLIEQGKVFYISKGTLKIANKQFSSLKNDYEMTLNGETSIIPCEDSNDVPMLQCDFVSIADLESREKDTILDVIGVCKNAEDVARIMTKNSREVSKRNIQLIDMSGRVIQLTMWGSDAETFDGSGQPILAIKGARLSDFGGRSLSTLYSSTVMINPDIPEAYKLRGWYDKEGHALDGQSMTELRGPGGGGNTNWKTLAEVKNEHLGHGDKADYFSCIATIVYIRKENCLYQACPSKDCNKKVVDQQNGMFRCEKCDKEFPDFKYRLMLSANIADFGDNQWVTCFQDTAETLLGQNSSYLGQLKDTNEAAFDEVFQHANFNTFVFRNRVKLETYNDESRIKVTVVDAKPVDHREYSKRLIINIRKLAAQ
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
What are the official names of this protein?
Replication protein A 70 kDa DNA-binding subunit, RP-A p70, Replication factor A protein 1, RF-A protein 1.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: FADR_SALSV
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTALRQHPDKAQEVLATAHEVADHADAFADLDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSSLCEQGAHDQVYETVRRYGHDSGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPAI_ARATH
Sequence: MSSTCSSPSAVEDPELGFRIDLDWTAGDSEDQVALRLESQLMVALPAPHDTVVVELKGIGDDDEGGLENVGLEMRVEKRREPLRAVTLMKAVGSGQQYDGVGVLTRLMRSDMMPAAIPAPAIDVASSCGVHWKTVTSLSLSGCGLLVMPVEVTELPLLEKLCLEHNKLSVLPPEIGKLKNLKILRVDNNMLISVPVELRQCVGLVELSLEHNKLVRPLLDFRAMAGLRILRLFGNPLEFLPEILPLHQLRHLSLVNIRIVSDENLRSVNVQIETENTSYFGASRHKLSAFSPLIFRSSSCHHPLLASTLVKIMQDEGNRSVIGKDENAVRQLISMITSDNQHVVEQACVALSSLARDVGVAMQLMKCDIMKPTETVLKSSSPDEVISVLQVVVTLAFVSDSVSQKMLTKDMLKALKSLCAHKNPEVQRQALLAVGNLAFCLENRRILITSESLRELLMRLIVTPEPRVNKAAARALAILGENEILRRSIKGRQVPKQGLRILTMDGGGMKGLATVQILKEIEKGSGKPIHELFDLICGTSTGGMLAIALGVKLMTLEQCEEIYKNLGKLVFAESVPKDNEAASWREKLDQLYKSSSQSFRVVIHGSKHSANEFERLLKEMCADEDGDLLIESAVKNVPKVFVVSTLVSVMPAQPFIFRNYQYPVGTPEMSYAFSDHSGGSTLTSSTASDQAGYYKQSAFMGSCKHQVWQAIRASSAAPYYLDDFSVDSYRWQDGAIVANNPTIFAIREAQLLWPDTKIDCLVSIGSGSVPTRVRKGGWRYLDTGQVLIESACSVERVEEALSTLLPMLPEIQYFRFNPVDDRCGMELDETDPAIWLKLEAAIEEFIQSNPQVFKNVCERLTLPFLNDEKWCDNLKPRFMNGKLPNSRVESSPSLGWRRNVLLMEAQHSPDSGRVKYHARALESFCSNNGIKLSSLHTTATPGCQKPSPGTAFPTPFTSPLITGSLPPSPLLFTPELGPQKFNRIDMVPPLSLDGGHVGKTVMSPPSSPPRQRQLYLPLRQMHEKLQNLPQVGILHLSLQNDSNGSILSWQNDVFVVAEPGDLADKFLQSVKVSILSVMQSNRRKAASVLSNICSISDLVRSKKCFQVGNIIHRYIGRQTLVMEDDQEIASFMFRRTVPSAHLTPDDIRWMVGAWRDRIIVFSGTFGPTQAVVKAFLDSGAKAVIGPSNEPQETPLITSQGSSEYNIGDQNGKFEIGEEEDEDEEVNEETEREEMEPPTPTSDWEDSDHEKTNRDGKYCGLWEDDEEEVSEFVCQLYDQLFRENSRVDVALQKALASHRKLRYTCHLPNV
What is the function of this protein?
Possesses non-specific lipolytic acyl hydrolase (LAH) activity.  Catalyzes the hydrolysis of the galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), and less efficiently the phoshpolipids phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), phosphatidylserine (PS) and phosphatidylinositol (PI).  Hydrolyzes phospholipids at both the sn-1 and sn-2 positions.  Involved in basal jasmonic acid production and promotes resistance to the necrotrophic fungal pathogen Botrytis cinerea.
What are the official names of this protein?
Phospholipase A I, AtPLA1.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.