PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_SYNP2
Sequence: MAIKRNQGHGLPPKRDPALGRDALTTSQALPEDQEQSANEDRIRPQRLGDYLGQKDLKEVLGIAIAAAKARREPLDHMLLYGPPGLGKTTMSLILAAEMGVNCKITAAPALERPRDISGLLVGLEAGDILFIDEIHRLNRMAEELLYPAMEDGRLDVTIGKGVSARTRSIPLKPFTLIGATTKVGALTSPLRDRFGLIQRLRFYEVDELIAIVHRSALILEQPITPEGALEIARRARGTPRIANRLLRRIRDYAQVKGYGEISQTVAATALDLYNVDALGLDWTDRLILETMLNHFGGGPVGLEAIAAATGEDSKTIEEVYEPYLLQIGFLNRTPRGRIVSAKARQHLGLIPVEQSTQLDFLP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: AVO1_YEAST
Sequence: MDTVTVLNELRAQFLRVCPEKDQMKRIIKPYIPVDEFNTEQCLDSSIRELYMNSDGVSLLPELESPPVSKDFMENYASLGKMRIMRENEGQKGKANQNLIGAEKTERDEEETRNLQDKSAKNTLIVEENGTLRYNPLNSSASNSLLNDDDHTSGKHHKTSSKEDSYLNSSMEMQKKSSKRSSLPFVRIFKSRRDHSNTSGNKNVMNTTNTRAKSSTLHPPGARHNKKGSKFDMNFDFDENLEEEDDDDDDDEEGDDIHSQFFQLDDDFDAKGSGASPAHKGINGMSNNKNNTYTNNRNSISILDDRESSNGNIGSASRLKSHFPTSQKGKIFLTDNKNDGQKSDSLNANKGIHGDGSSASGNGSVSRDGLTETESNNISDMESYINEKDLDDLNFDTVTSNINKTVSDLGGHESTNDGTAVMNRDSKDSRSNSNEFNAQNRDRITPGSSYGKSLLGSEYSEERYSNNDSSTMESGEMSLDSDMQTNTIPSHSIPMSMQKYGIYHGDDDSTLNNVFDKAVLTMNSSRHPKERRDTVISGKEPTSLTSSNRKFSVSSNLTSTRSPLLRGHGRTSSTASSEHMKAPKVSDSVLHRARKSTLTLKQDHSQPSVPSSVHKSSKEGNILIEKTTDYLVSKPKASQLSNMFNKKKKRTNTNSVDVLEYFSFVCGDKVPNYESMGLEIYIQASKKYKRNSFTTKVRKSSTIFEVIGFALFLYSTEKKPDNFEEDGLTVEDISNPNNFSLKIVDEDGEPFEDNFGKLDRKSTIQSISDSEVVLCKVDDAEKSQNEIETPLPFETGGGLMDASTLDANSSHDTTDGTINQLSFYKPIIGNEDDIDKTNGSKIIDVTVYLYPNVNPKFNYTTISVLVTSHINDILVKYCKMKNMDPNEYALKVLGKNYILDLNDTVLRLDGINKVELISKKDARELHLEKMKPDLKKPVLPTIQSNDLTPLTLEPLNSYLKADAGGAVAAIPENTKVTSKAKKISTKYKLGLAKQHSSSSVASGSVSTAGGLANGNGFFKNKNSSKSSLHGTLQFHNINRSQSTMEHTPDTPNGVGDNFQDLFTGAYHKYKVWRRQQMSFINKHERTLAIDGDYIYIVPPEGRIHWHDNVKTKSLHISQVVLVKKSKRVPEHFKIFVRREGQDDIKRYYFEAVSGQECTEIVTRLQNLLSAYRMNHK
What is the function of this protein?
Component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity.  TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway.
What are the official names of this protein?
Target of rapamycin complex 2 subunit AVO1, TORC2 subunit AVO1, Adheres voraciously to TOR2 protein 1.
What is the protein family that this protein belongs to?
Belongs to the SIN1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRMA_SALNS
Sequence: MTPEHLPTEQYEAQLAEKVARLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRLWHDGDDLYHIMFDQQTKSRIRVDTFPAASQLINTLMKAMIAGVRDNHALRHKLFQMDYLTTLSNQAVVSLLYHKKLDEEWREAATALRDALRAQGLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALEVTKDSKGDLLELYCGNGNFSLALARNFNRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTLAMNGVREFNRLQGIDLKGYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHTVSRLALFDQFPYTHHMECGVLLTAR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RBL_ATRRS
Sequence: MSPQTETKANVGFKAGVKDYKLTYYTPEYETLDTDILAAFRVSPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYEVLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEDMMKRAVFARELGVPIVMHDYLTGGFTANTTLSHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRLSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDYTEKDRSRGIYFSQSWVSTPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNTIIREASKWSPELAAACEIWKEIKFEFPAMDTV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL21_SYNPW
Sequence: MAETSTSQSAAPDTGTYAIVEASGQQFWLQPNRYYDLDRLQADVDATVTLDNVLLVKDATGTTLGKPYVKDASVELKVMAHRRGPKVIVYKMRPKKKTRRKNGHRQELTRVMVQSISVGGKSIS
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: NAC6_ARATH
Sequence: MKILPVGSRFCPTDLGLVRLYLRNKVERNQSSFITTMDIHQDYPWLLPHVNNPLFNNNEWYYFVPLTERGGKILSVHRKVAARGGSEGGTWRSNDGKKEIKDGHMQKGDGLRASDDLQKVVLCRIRYKKEANVNEFGLVNHQAHQTQDALTGFADQLEMMLEGQEDREQKEEADLTGFADSLETMLEGQEDHEQPEDADLTGFADSLETMLEGHEDREQPEEAELTVTQQQQQQQQQQQRQEDCDVTQEQEKDDVMVLINNPNDALALGNYEIIDLTRVDK
What are the official names of this protein?
NAC domain-containing protein 6, ANAC006.
What are the subcellular locations of this protein?
Nucleus.
Protein: RHO_MYCLE
Sequence: MTETDLITVGENTDDTELTNAVTTDTPDVKATAATVSLGSLSTMVLPELRALANQAGVKGTSGMRKSELIAAIEECRGQANGTSVNDGPSRDHGGSATAISTEALAAQEEQNYAIVEVSRRERRGASREADVTAGTSTAEATESDCQGTADDDTRTLQGGQSDTKTEERGPDVGNDQGVEQQSSSLQPRGDDDGEGRQGRRGRRFRDRDRRRRGERSGDGAEAELRQDDVVQPVAGILDVLDNYAFVRTSGYLAGPHDVYVSMSMVRKNGLRRGDAVTGAVRVPREGEQGHQRQKFNPLVRLDSINGGSVEDAKKRPEFGKLTPLYPNQRLRLETTPDRLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQDIANAITRNNLECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDMVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLSPDEFGIVHKLRRVLSGLDSHQAIDLLMSQLRKTKTNYEFLVQVSKTTPGSMDDD
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: CCN6_HUMAN
Sequence: MQGLLFSTLLLAGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPCKCPQQKPRCPPGVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCEFNQVHYHNGQVFQPNPLFSCLCVSGAIGCTPLFIPKLAGSHCSGAKGGKKSDQSNCSLEPLLQQLSTSYKTMPAYRNLPLIWKKKCLVQATKWTPCSRTCGMGISNRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIFSELKIL
What is the function of this protein?
Plays a role in mitochondrial electron transport and mitochondrial respiration (PubMed:27252383).  Through its regulation of the mitochondrial function may play a role in normal postnatal skeletal growth and cartilage homeostasis (PubMed:27252383, PubMed:10471507).
What are the official names of this protein?
Cellular communication network factor 6, CCN family member 6, WNT1-inducible-signaling pathway protein 3, WISP-3.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted. Mitochondrion. Note=Associated with membranes.
Protein: RRF_FLAPJ
Sequence: MTEEIDFILDSTKESMEGSIAHLEKEFLNIRAGKASPAMLGSVFVDYYGSATPLSQVAKISVPDARTITLQPFEKNMLQVIEKAIMIANIGFNPMNNGDVIIISVPPLTEERRRELAKQAKTEAEDAKIGVRNVRKDSNSDIKKLEKEGTSEDACKIAEESVQKLTDSFIRKVDELLVVKEAEIMKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOTA_ASPSM
Sequence: MANDNRRTVTVYGATGAQGGAVARSLLKNHAFKVRAITRKPDSEAAKALRALGAEIVQGDGWSKEQMVAAFSGSWAAFVNTNSDDPCFVDGHPPTEVDLGKIIIDAIIEAGTVKHLVYSSFVDTSSFTNGQASIKAADMKAKVQRYAADSGHFDTVCPLYQGWYMGIFLRQDYARALGGFPYFQDEDGFRTLHLPRWGTHTDMPIPWISLEDDFGDIVHGIFLEPENYNRRVVPTVSDVCTYPEVMDAVHALATGQKAQYIPVTDWEAHFGDSHHGRESLTIFKFGHFTNGKYFGHEPISTDISAYLKSKAAEAQGKDPSDRKLITLSEWFEKHVAPLI
What is the function of this protein?
NmrA-like family domain-containing oxidoreductase; part of the gene cluster that mediates the biosynthesis of notoamide, a fungal indole alkaloid that belongs to a family of natural products containing a characteristic bicyclo[2. 2. 2]diazaoctane core (PubMed:20722388).  The first step of notoamide biosynthesis involves coupling of L-proline and L-tryptophan by the bimodular NRPS notE, to produce cyclo-L-tryptophan-L-proline called brevianamide F (PubMed:20722388).  The reverse prenyltransferase notF then acts as a deoxybrevianamide E synthase and converts brevianamide F to deoxybrevianamide E via reverse prenylation at C-2 of the indole ring leading to the bicyclo[2. 2. 2]diazaoctane core (PubMed:20722388).  Deoxybrevianamide E is further hydroxylated at C-6 of the indole ring, likely catalyzed by the cytochrome P450 monooxygenase notG, to yield 6-hydroxy-deoxybrevianamide E (Probable).  6-hydroxy-deoxybrevianamide E is a specific substrate of the prenyltransferase notC for normal prenylation at C-7 to produce 6-hydroxy-7-prenyl-deoxybrevianamide, also called notoamide S (PubMed:20722388).  As the proposed pivotal branching point in notoamide biosynthesis, notoamide S can be diverted to notoamide E through an oxidative pyran ring closure putatively catalyzed by either notH cytochrome P450 monooxygenase or the notD FAD-linked oxidoreductase (Probable).  This step would be followed by an indole 2,3-epoxidation-initiated pinacol-like rearrangement catalyzed by the notB FAD-dependent monooxygenase leading to the formation of notoamide C and notoamide D (PubMed:22188465).  On the other hand notoamide S is converted to notoamide T by notH (or notD), a bifunctional oxidase that also functions as the intramolecular Diels-Alderase responsible for generation of (+)-notoamide T (Probable).  To generate antipodal (-)-notoaminide T, notH' (or notD') in Aspergillus versicolor is expected to catalyze a Diels-Alder reaction leading to the opposite stereochemistry (Probable).  The remaining oxidoreductase notD (or notH) likely catalyzes the oxidative pyran ring formation to yield (+)-stephacidin A (Probable).  The FAD-dependent monooxygenase notI is highly similar to notB and is predicted to catalyze a similar conversion from (+)-stephacidin A to (-)-notoamide B via the 2,3-epoxidation of (+)-stephacidin A followed by a pinacol-type rearrangement (Probable).  Finally, it remains unclear which enzyme could be responsible for the final hydroxylation steps leading to notoamide A and sclerotiamide (Probable).
What are the official names of this protein?
NmrA-like family domain-containing oxidoreductase notA, Notoamide biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
Protein: DPF1_HUMAN
Sequence: MATVIPGPLSLGEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAPLKKEGGLPEGPVLEALLCAETGEKKIELKEEETIMDCQKQQLLEFPHDLEVEDLEDDIPRRKNRAKGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLAEEEGEENAERHALPFHRKNNHKQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAYITLT
What is the function of this protein?
May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor.  Belongs to the neuron-specific chromatin remodeling complex (nBAF complex).  During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.  The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.  As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF).  The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.  The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
What are the official names of this protein?
Zinc finger protein neuro-d4, BRG1-associated factor 45B, BAF45B, D4, zinc and double PHD fingers family 1.
What is the protein family that this protein belongs to?
Belongs to the requiem/DPF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PVK1_PANVI
Sequence: GSSGLIPMGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, PanVi-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RM17_YEAST
Sequence: MKVNLMLKRGLATATATASSAPPKIKVGVLLSRIPIIKSELNELEKKYYEYQSELEKRLMWTFPAYFYFKKGTVAEHKFLSLQKGPISKKNGIWFPRGIPDIKHGRERSTKQEVKLSDDSTVAFSNNQKEQSKDDVNRPVIPNDRITEADRSNDMKSLERQLSRTLYLLVKDKSGTWKFPNFDLSDESKPLHVHAENELKLLSGDQIYTWSVSATPIGVLQDERNRTAEFIVKSHILAGKFDLVASKNDAFEDFAWLTKGEISEYVPKDYFNKTEFLLADN
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L17, mitochondrial, Mitochondrial large ribosomal subunit protein mL46, YmL17/YmL30.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL46 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: EMRE_HUMAN
Sequence: MASGAARWLVLAPVRSGALRSGPSLRKDGDVSAAWSGSGRSLVPSRSVIVTRSGAILPKPVKMSFGLLRVFSIVIPFLYVGTLISKNFAALLEEHDIFVPEDDDDDD
What is the function of this protein?
Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria (PubMed:24231807, PubMed:26774479, PubMed:27099988).  Required to bridge the calcium-sensing proteins MICU1 and MICU2 with the calcium-conducting subunit MCU (PubMed:24231807).  Plays a central role in regulating the uniplex complex response to intracellular calcium signaling (PubMed:27099988).  Acts by mediating activation of MCU and retention of MICU1 to the MCU pore, in order to ensure tight regulation of the uniplex complex and appropriate responses to intracellular calcium signaling (PubMed:27099988).
What are the official names of this protein?
Essential MCU regulator, mitochondrial, Single-pass membrane protein with aspartate-rich tail 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SMDT1/EMRE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=MAIP1 is required to assist sorting of EMRE/SMDT1 into mitochondrion by protecting EMRE/SMDT1 against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB) (PubMed:27642048).
Protein: INS_DANRE
Sequence: MAVWLQAGALLVLLVVSSVSTNPGTPQHLCGSHLVDALYLVCGPTGFFYNPKRDVEPLLGFLPPKSAQETEVADFAFKDHAELIRKRGIVEQCCHKPCSIFELQNYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYY_SALNS
Sequence: MASSNLIKQLQERGLVAQVTDEDALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVAKIRKQVAPFLDFDCGENSAIAANNYDWFGSMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDQGISFTEFSYNLLQGYDFACLNKLHGVALQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMDIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLVAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDAELQPSRGQARKTIASNAVTINGEKQSDPEYIFNDEDRLFGRYTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_BIFLO
Sequence: MGRVVSYNEDVPRCTFCGKTEHQVRKLVAGPNASICDECIALCVDIISEERVKDAEVNSLSLPKPAQIFDYLNRYVIGQENAKRALSVAVYNHYKRVNMELQESAEQLDGNNGHSGQTSKQAKQSVPTQTRATRRSNDPLADVEVAKSNILLLGPTGVGKTYLAQALARVMNVPFVITDATTLTEAGYVGDDVETVLQRLLQAADGDVSRAQHGIIYIDEIDKIARKSGENTSITRDVSGEGVQQALLKILEGTIASVPLEGTRKHKEQDVAQMDTRGILFICGGAFVGLTDIVRKRLGRRETGFGANWHDADMKDEELLEQVNADDLAEFGLLPEFIGRLPVTSVLKELTVDDLTAILTQPANALIKQYRKLFAVDGVDLQFTEQAIRAIADIAIKQGTGARGLRSIIERTLQDTMFQLPSLDDVRQVIVDKASVEGSSTPKLLREAVDVPQGRLKVAQSVLLDRVRTHEA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ILVD_BIFAA
Sequence: MEMRSAKLMNGRVFAGARALYRAAGVDGKDFGKPIIAIANSFDEFLPGHVHLNKVGRLISDAIKEAGGIPREFNTMAVDDGIAMGHTGMLYSLPSRDIIADTVEYQVNAHCADALICIPNCDKVVPGMLMAALRLNIPTVFVSGGPMEAGTTVLPDGTVKKNTDLIDVMYASADDNLNEEDLLAYEKTVCPTCGSCAGMFTANSMNCLTEAIGLALPGNGTILASHSYRKDLFKRAAEQVVKIAKQYYDDDDDSVLPRSIATKKAFENAMTMDVAMGGSTNTVLHILAMAQSADVDFTLDDIERISHTVPCICKASPSGEWEISDVHRAGGITGILGELDRAGKLHRDVHSIDYKSLEDKLNDWDIMRDTCTEEAKQMYLAAPGHIVSPEPWTHTTLFDSLDRDRVNGAIHDIDHPAVTEGGLAVLRGNLAPDGCVVKTAGVPKEIWTFRGPALVVESQEQAIEVILNDTLKPGMALVIRYEGPKGGPGMQEMLYPTSFVKGKGIGKQVAMLTDGRYSGGSSGLAIGHIAPEAANKGPIALIKNGDIINIDIPNRTVNVELSDEELAQRRAELEAGDGYVAHRDRKVSQALKAYAAFARSADKGATRDPELIDKLSGLA
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RS10_BURP1
Sequence: MQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRSPHVNKTSRDQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: YBEY_PSET1
Sequence: MNTELDLQIACEFDNLPSEAQFALWADKALSQYRDESELTIVISDEAQSQQLNNDYRGKNKPTNVLSFEFEAPPGIDIPLVGDLVICPAIVLAEAIEQEKSFHDHFAHMVIHGCLHLLGFDHIKSEDAFEMESIEKQLLAELNIADPYRDEI
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H32_ASPOF
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRFRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVAALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.