PharMolix/UniProtQA huggingface dataset:
Protein: PCPF_SPHCR
Sequence: MGLLIDGVWRDAWYDTKSSGGRFVRKESQYRGGLDAGFRGEPGRYHLYAGFACPWAHRVLIMRALKGLEEMISVSMVNAYMGENGWTFLPGDDVVPDSINGADYLYQVYTAADPTYTGRVTIPILWDKVEKRILNNESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDRINARVYETLNNGVYRSGFATTQEAYEEAFYPLFDTLDWLEEHLTGREWLVGDRLTEADIRLFPTLVRFDAIYHGHFKCNLRRIADYPNLSRLVGKLASHERVAPTINLRHAKAHYYGSHPSVNPTGIVPVGPAQPLPGLTLQS
What is the function of this protein?
Catalyzes glutathione (GSH)-dependent reduction of glutathionyl-hydroquinones (GS-HQs) to the corresponding hydroquinones.  Can act on halogenated substrates such as GS-2,6-dichloro-p-hydroquinone (GS-DiCH) and GS-trichloro-p-hydroquinone (GS-TriCH).  Involved in the degradation of pentachlorophenol (PCP), a toxic pollutant.
What are the official names of this protein?
Glutathionyl-hydroquinone reductase PcpF, GS-HQR.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Xi-class GSH transferase family.
Protein: ISPD_STRCO
Sequence: MSDESRPSPAETPATTFAETSAETSAAGRSPARTAAVIPAAGRGVRLGPGAPKALRALGGTPMLIHAVRAMAASRAVSLVVVVAPPDGAGEVKSLLDAHALPERTDFVVVPGGETRQESVRLGLDALPPEYGIVLVHDAARPLVPVDTVDAVIDAVREGAPAVVPAVPLADTVKQVEPAAAPGEPEPVVATPERARLRAVQTPQGFDRATLVRAHGTVTDDVTDDASMVEQLGLAVVVVPGHEEAFKVTRPLDLVLAEAVLARRRLNDGF
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: AROA_NOSS1
Sequence: MDTIAIPALNRPVDATVEIPGSKSITNRALLVAALAQGDSTLENALFSEDSEYFAKCVEQLGIPITLHPHLAQIQVSGKGGDIPAKQADLFVGLAGTAARFITALVALGNGEYRLDGVPRMRERPMGDLVTVLQNSGITINFEGNSGFMPYTIYGQQFAGGHFRLKANQTSQQLSALLMIAPYAQQDTTIEVEGTLVSQSYVKMTCRLMADFGVDVTQTDDNQFHIKAGQRYQARHYTIEPDASNASYFFAAAAVTGGRVRVNHLTKQSCQGDILWLNVLEQMGCQVIEGADYTEVIGPEQLQGIDIDMNDMSDLVQTLGAIAPYASSPVIIRNVEHIRYKETERIRAVVTELRRLGVKVEEFADGMKIEPTPITPAAIETYHDHRMAMAFAVTGLKTPGIVIQDPGCTAKTFPDYFTRFFKMID
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_EDWI9
Sequence: MQTSPLLESLMEALRCLPGVGPKSAQRMAFHLLQRDRSGGMRLAQALTRAMSEIGHCRDCRTFTEQEVCTICTNARRRENGQICVVESPADIHAIEQTGQYSGRYFVLMGHLSPLDGIGPQDIGLDRLEVRLSQEAVSEVILATNPTVEGEATANYIAEMCAAHGVLASRIAHGVPVGGELEMVDGTTLSHSLAGRHPVTR
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SEC31_YEAST
Sequence: MVKLAEFSRTATFAWSHDKIPLLVSGTVSGTVDANFSTDSSLELWSLLAADSEKPIASLQVDSKFNDLDWSHNNKIIAGALDNGSLELYSTNEANNAINSMARFSNHSSSVKTVKFNAKQDNVLASGGNNGEIFIWDMNKCTESPSNYTPLTPGQSMSSVDEVISLAWNQSLAHVFASAGSSNFASIWDLKAKKEVIHLSYTSPNSGIKQQLSVVEWHPKNSTRVATATGSDNDPSILIWDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSSGRDNTVLLWNPESAEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIEVQTLQNLTNTLDEQETETKQQESETDFWNNVSREESKEKPTVFHLQAPTWYGEPSPAAHWAFGGKLVQITPDGKGVSITNPKISGLESNTTLSEALKTKDFKPLINQRLVKVIDDVNEEDWNLLEKLSMDGTEEFLKEALAFDNDESDAQDDANNEKEDDGEEFFQQIETNFQPEGDFSLSGNIEQTISKNLVSGNIKSAVKNSLENDLLMEAMVIALDSNNERLKESVKNAYFAKYGSKSSLSRILYSISKREVDDLVENLDVSQWKFISKAIQNLYPNDIAQRNEMLIKLGDRLKENGHRQDSLTLYLAAGSLDKVASIWLSEFPDLEDKLKKDNKTIYEAHSECLTEFIERFTVFSNFINGSSTINNEQLIAKFLEFINLTTSTGNFELATEFLNSLPSDNEEVKTEKARVLIASGKSLPAQNPATATTSKAKYTNAKTNKNVPVLPTPGMPSTTSIPSMQAPFYGMTPGASANALPPKPYVPATTTSAPVHTEGKYAPPSQPSMASPFVNKTNSSTRLNSFAPPPNPYATATVPATNVSTTSIPQNTFAPIQPGMPIMGDYNAQSSSIPSQPPINAVSGQTPHLNRKANDGWNDLPLKVKEKPSRAKAVSVAPPNILSTPTPLNGIPANAASTMPPPPLSRAPSSVSMVSPPPLHKNSRVPSLVATSESPRASISNPYAPPQSSQQFPIGTISTANQTSNTAQVASSNPYAPPPQQRVATPLSGGVPPAPLPKASNPYAPTATTQPNGSSYPPTGPYTNNHTMTSPPPVFNKPPTGPPPISMKKRSNKLASIEQNPSQGATYPPTLSSSASPLQPSQPPTLASQVNTSAENVSHEIPADQQPIVDFLKEELARVTPLTPKEYSKQLKDCDKRLKILFYHLEKQDLLTQPTIDCLHDLVALMKEKKYKEAMVIHANIATNHAQEGGNWLTGVKRLIGIAEATLN
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
What are the official names of this protein?
Protein transport protein SEC31, Protein WEB1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC31 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EFG_CARRP
Sequence: MNDIKNIRNIGIIAHVDAGKTTTTERILFFSGFSHKIGEVHTGNTITDWMKQEQERGITITSASVTFFWKTNFYNSSINLIDTPGHVDFTIEVERSLRVLDGAVILICASSGIQPQTETVWNQSEKFNIPKILFVNKLDRIGAKYLSIIENIKKKFFCNILIINLNIGIENSFSGIIDLINMKELIWNNSQLEIRNITNKNFDISNKYRNILLETLSEYDDIFLEKYINSNFSIKDIIESIRKLVILNKIIPIACGSSLKNKGIEFLLDSIVNFLPSPIDIGIKNVSNINYSVNIKSKFLALLFKVFNDPYLGLLSFIRIYSGKIEPGQIIFNNSKNIKEKIFRIIRMFANSKKDLNIASAGDIVVLIGLKNSFTGDTLSFDNEKVLLEKINIPLPVISVSVEPIVKNDYEKLLNLINKFCKEDPSLLFKINENTGELILSGMGELHLEIIIDRINNEFNIKTKTSKPQVSYKESIKKTIIQEGKYIKQTGGRGQYGHVVLKIEPILIEKDDFIFKIEVVGGVIPKEYFLSIEKGILEQIKCGVVLGYPVTKIKITLINGSFHPVDSSEYAFKNAASIALKEALKKANSFLLEPIMKVEIISPKEYLGIVISDISKKRGNIISVVDNNNNLKIINSLIPLRELFGYSTDLRSNTKGRANYNMEFHNYSETPNYILEKIKKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF35_NEOYE
Sequence: MSHFTKIQTTIQDLNLLKHALTDLGLIWQMNSSHIKVGENNQHKVDILIKQDNLSHIGFTWNDNRYHLVADLQLWEQPWSLEVFLDKLSQKYAYYSIIEETKKQGFEKMQQISQKDGSIKLIVQRWNY
What are the official names of this protein?
Uncharacterized protein ycf35.
What is the protein family that this protein belongs to?
Belongs to the ycf35 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KLEB2_ECOLX
Sequence: MPNRKIEIVTTNCRRCGKSISTLSRSLIGADALREELGGICGDCITPEERQRIEQGTLLAALRQCAAAGTS
What are the official names of this protein?
Protein KleB, KcrA2 protein.
Protein: PSUG1_RHIL3
Sequence: MLSRSQDKTMTKPISPLLPIAYSKEVASAKQRGAPLVALESTIITHGMPYPGNIEMARSVEAIIREQGAVPATIAVIHGTLHIGLEAAELEQLAKATEVMKVSRADLAFAIAERRTGATTVAATMIAAARAGIRVFATGGIGGVHRGAEESFDISADLEELARTGVIVVCAGAKAILDIPKTLEVLETRGVPVVTYESEEFPAFWSRSSGIRSPLSLNSPAAIANFQTVREQLGIDGGMLVANPVPEADEIASEEMEIYIERALDSAERDEVTGKAVTPYLLSTIFDLTDGQSLKTNIALVENNARLAAEIAVALGE
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase 1, PsiMP glycosidase 1.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: PUR9_CHLP8
Sequence: MSDPVIKRALVSVSDKTGIVDFCRELASMGVEIFSTGGTLKALQDAGIAAESISTITGFPEIMDGRVKTLHPKIHGGLLAVRDNAEHQQAARENGIEFIDLVAVNLYPFEATIAKADVSFEEAIENIDIGGPSMLRSAAKNNESVTVITDAADYATVLDEMKSNGGATTRTTRLTLAAKVYALTSRYDTAIAAYMAKAAGVEGANDTMTVKLEKELGMRYGENPHQSAGLYKMDDGNGTRSFGAIFEKLHGKELSYNNMLDIAAATGIIEEFRGEEPSVVIVKHTNPCGVAQAPTLCEAYRKAFSTDTQAPFGGIIAFNRPLDMETANAVNEIFTEILIAPAFEEGVLDLLMKKKDRRLVLQKQPLPKAGWEFKSTPFGMLVQERDSKMVAPEELKVVTKRQPTEEELADLMFAWKIARHIKSNTILYVKNRQTFGVGAGQMSRVDSSKIARWKASEVGLDLKGSVVASDAFFPFADGLLAAAEAGVTAVIQPGGSIRDNEVIEAADANNLAMVFTGMRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CLPX_CORGB
Sequence: MARMQESADLLKCSFCGKSQKQVKKLIAGGAVYICDECIELCNEIIEEELGQAQHDEQERNELPKPSEISAFLDTYVIGQDPAKRILSVAVYNHYKRLRASETIGRRRNDEPETELVKSNILMLGPTGSGKTFLAQTLAKLLDVPFAIADATSLTEAGYVGEDVENILLKLLQAADFDVERAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVAAIPPQGGRKHPNQDFIQLDTTNILFIVAGAFSGLEKVIADRNGKKGLGFGVEVSSKKEEADIVDIFKDVRPEDLVKFGLIPEFIGRLPVVATVSNLDQKSLVKVLTEPRNSLVKQYQRLFEMDDAVLTFTDDALEEIANQALERKTGARGLRAIMEEILVPIMYDLPDREDVGEVIINGAVARGEAEPEMLEAVAEEKTA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: MAMI_MAGGM
Sequence: MPSVIFGLLALAIGLLGLTAWWWSVTEFLRGAVPVALIIFGLVALAAGVQSVRVPPAGKRANSDPNIDG
What is the function of this protein?
May be involved in an early stage of magnetosome nucleation (Probable).  Not essential for formation of magnetosome membrane vesicles, it is probably functionally redundant with other proteins (PubMed:27286560).  May bind magnetite (By similarity).  One of 7 genes (mamLQBIEMO) able to induce magnetosome membrane biogenesis; coexpression of mamLQRBIEMO in a deletion of the 17 gene mamAB operon restores magnetosome vesicle formation but not magnetite biosynthesis (PubMed:27286560).
What are the official names of this protein?
Magnetosome protein MamI.
What is the protein family that this protein belongs to?
Belongs to the magnetosome MamI protein family.
What are the subcellular locations of this protein?
Magnetosome membrane; Multi-pass membrane protein. Note=Tagged protein is found in punctate chains.
Protein: TPIS_PIG
Sequence: MAPARKFFVGGNWKMNGRKNNLGELINTLNAAKLPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVANGAFTGEIGPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWNKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKTHVPEAVAHSTRIIYGGSVTGATCKELASQPDVDGFRVSGASLKPEFVDIINAK
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP4A_MOUSE
Sequence: MALRACGLIIFRRHLIPKMDNSTIEFLLLQASDGIHHWTPPKGHVDPGENDLETALRETREETGIEASQLTIIEGFRRELNYVARQKPKTVIYWLAEVKDYNVEIRLSQEHQAYRWLGLEEACQLAQFKEMKATLQEGHQFLCSTPA
What is the function of this protein?
Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP (By similarity).  Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro (PubMed:32432673).
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: GL_HCMVP
Sequence: MCRRPDCGFSFSPGPVILLWCCLLLPIVSSAAVSVAPTATEKVPAECPELTRRCLLGEVFQGDKYESWLRPLVNVTGRDGPLSQLIRYRPVTPEAANSVLLDEAFLDTLALLYNNPDQLRALLTLLSSDTAPRWMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYERSIFTEHVLGFELVPPSLFNVVVAIRNEATRTNRAVRLPVSTAAAPEGITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELKQTRVNLPAHSRYGPQAVDAR
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH (By similarity).  In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope.  The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA.  The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: Y143_MYCPN
Sequence: MSHKDFNGLQAPQLLSSSSPVAKKQSSHKLRHALKHARYLNHSSKRTLKHALELHEDNQVLLEKEGSPNFQDWLSKQPGVNKTSLKYNKSLGSWISKESKPKKRFPPYFTYKGSKTTPEEAKALQQMKQSQKRFFHENMHSFLNEVAHNPMIQRFKQKQAKRAANTRQRTYKYRQ
What are the official names of this protein?
Uncharacterized protein MPN_143.
Protein: NUOB_PSEPW
Sequence: MQYNLTRIDPDAPNEQYPVGERETVTDQLLEDQVHKNIYMGKLEDVLRGAVNWGRKNSLWPYNFGLSCCYVEMTTAFTAPHDIARFGAEVIRASPRQADFMVIAGTCFIKMAPIIQRLYEQMLEPKWVISMGSCANSGGMYDIYSVVQGVDKFLPVDVYVPGCPPRPEAFLQGLMLLQESIGQERRPLSWVVGDQGIYRAEMPAQKDLRREQRIAVTNLRSPDEV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: T2R16_GORGO
Sequence: MIPIQLTVFFMIIYVLESLTIIVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNBFCSYFNLNYVLCNLTITWEFFNILTFWLNSLLTVFYCIKVSSFTHHIFLWLRWRILRLFPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLEKFHQYEFQAHTVALVIPFILFLASTILLMASLTKQIQHHSTGHCNPSMKAHFTALRSLAVLFIVFTSYFLTILITIIGTLFDRRCWLWVWEAFVYAFILMHSTSLMLSSPTLKRILKGKC
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 16, T2R16.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU4LM_VAMBI
Sequence: MSLTYMNMFMAFTISLLGLLMYRSHMMSSLLCLEGMMLSLFVMMTMTILNTHLTLASMIPIILLVFAACEAALGLSLLVMVSTTYGMDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SSRP_ANAD2
Sequence: MKGKAGGKAADAAEKVAASNRRARFDYDVEDTWEAGLVLTGSEVKSLREGNVNLSDAYAMPRGEELWLLNCRIGEYQQAAHFGHAPLRDRKLLMNRAEIDRVRGKVEQRGYTLVPLRIYFKQGWAKVELGLARGRSHEDRRGAIAERESKREMDRALARGRRR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y877_METJA
Sequence: MDANLLGEKYAISVGVDIKSLRMWLIILSCVLTATVVAFTGPIAFVGITCPILARMICGTSKHIYVIPVTMLLGAVFLVVADILTRPGVLISSTNVLPLLCPLSIIGAPIAIIIYLKIRKMGI
What is the function of this protein?
Probably part of a binding-protein-dependent transport system.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Putative ABC transporter permease protein MJ0877.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS14_METFK
Sequence: MAKICMIEREQKRRDTVKKYAAKRAELLAVINDANASAEDRRAARQKLQSLPRNSSPVRQRNRCALTGRPRGVFSKFGIARSKLRELMMRGEVPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ANM7_AEDAE
Sequence: MHSDSDDYFSGDDDDFDRQQEIARSAFADMCHDWERNQKYDRALQLTIERLHCEGKEAHVLDIGTGSGLLSMMAVRAGADSVTACEAFRPMADCAERVIASNGMGDRIRLVKKKSTELKVGAGKDMERKANVLVTELFDTELIGEGAIATYRHALQFLLEEGCRVIPDKATVFAQVVECPLAMSWQTPKLLCSSDGDVLLRVPEEMVNCRGSSAVFDVQLSQLPLESFNALSEPIPVFEFDWSSREALKFKRHSRNLLKVQSSGIPQAVFMWWDLKMDLEGTVLLSCAPFWAHPDFEGLKTQKQNDSIPEPNLIPWRDHWMQAIYFLPHSKTPLAKGEEIALDAFHDEFSWWFGLNDLSLDPGHCSCGMHIAYSRSRIGQLNDGPRNKRILNYLEEVLDKNSVVLVLGDGSLLGLSIRAMGAKKVILVETNQTSRHCMERFVEHNGLENVEILSCLDDLTPDATADITHIFGEPFFTSAILPWENAIQFIWELNRVKALLNHEVSVIPHSFSIYGVAVEFLDLQKISAPLGTCEGFDLSLMDRMIEEHSKVADSPVEAQPLWEYPCLPLGPKCKMITINVAEGSQNQLEQGKITLTRHHEIKECNGIALWAEWHMGKNVSPKNTISSGPLSVIDEASELPVRPLQWNSNWRQGVHLLRKPLEESKMFLSWTVKYNAQLKTCYFKFD
What is the function of this protein?
Essential arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).  Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3 (By similarity).
What are the official names of this protein?
Protein arginine N-methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
Protein: H16ZA_CYRHA
Sequence: MNTVRVAFLLVFVLAVSLGQADKDENRMEMQEKTEQGKSYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDSRCCSGLVCLKPTLHGIWYKSHYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1x, U11-TRTX-Hhn1x, Hainantoxin-XVI-27, HNTX-XVI-27.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3691_BRUME
Sequence: MNRFIAFFRSVFLIGLVATAFGALPARAANETAPDYALSMHGDVALPADYTHFPYTNPDAPKKGSLTVGVVGTFDSLNPFVLKSMRTTARGLYNDGEFGNMVYQTLMLRSRDEPFTLYSLLAEKVAIDPERKWVEFTLNPKAKWSDGQPVTVDDVLFTYDILTEKGRPPYNSRMSRVAKIEKTGERSVRFTFNEKSDREFPMLIAGSMPVLPKHAINRDTFGNSTLEPPIGSGPYVVASVQPGQRIVYKRNPDYWGKDLPSQRGFNNFDKISIEYYRNETSLFESFKKGILDIFIEGNPIRWEKLYDFPAVEQGKVIKDTFEKGTPADMLGFVFNTRRPIFADRRVRQALGLLFDFEWANSNLFAGQYRRTQSFWEGSQLSSVGRPADARERELLAPFPGAVREDVMNGTWHPPVTDGSGHDRVPAKKAYDLLSQAGFQFKDGMAIDPTGKPFAFEIMTRSPDEEKIALAYQRNLSRLGIAVEIHTVDDAQYQQRLQTFDYDMILGALASSLSPGNEQWLRWGSASRDVQGSFNFAGVADPAVDAMIEALLAARNRADFVSAVRALDRVLISGDYYVPLYHLPYQWVARWDRIEHPQKTPLSGYQLPAWWHTSQ
What are the official names of this protein?
Putative binding protein BMEII0691.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PCDB2_HUMAN
Sequence: MEAGEGKERVPKQRQVLIFFVLLGIAQASCQPRHYSVAEETESGSFVANLLKDLGLEIGELAVRGARVVSKGKKMHLQFDRQTGDLLLNEKLDREELCGPTEPCVLPFQVLLENPLQFFQAELRIRDVNDHSPVFLDKEILLKIPESITPGTTFLIERAQDLDVGTNSLQNYTISPNFHFHLNLQDSLDGIILPQLVLNRALDREEQPEIRLTLTALDGGSPPRSGTALVRIEVVDINDNVPEFAKLLYEVQIPEDSPVGSQVAIVSARDLDIGTNGEISYAFSQASEDIRKTFRLSAKSGELLLRQKLDFESIQTYTVNIQATDGGGLSGTCVVFVQVMDLNDNPPELTMSTLINQIPENLQDTLIAVFSVSDPDSGDNGRMVCSIQDDLPFFLKPSVENFYTLVISTALDRETRSEYNITITVTDFGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALQSLDYEALQAFEFRVGAADRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLRERDAAKQRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLLLPEAAPAQAQADLLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGQMVDVSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNFVAQGAERVSEANPSFRKSFEFT
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-2, PCDH-beta-2.
Protein: G137A_HUMAN
Sequence: MESNLSGLVPAAGLVPALPPAVTLGLTAAYTTLYALLFFSVYAQLWLVLLYGHKRLSYQTVFLALCLLWAALRTTLFSFYFRDTPRANRLGPLPFWLLYCCPVCLQFFTLTLMNLYFAQVVFKAKVKRRPEMSRGLLAVRGAFVGASLLFLLVNVLCAVLSHRRRAQPWALLLVRVLVSDSLFVICALSLAACLCLVARRAPSTSIYLEAKGTSVCQAAAMGGAMVLLYASRACYNLTALALAPQSRLDTFDYDWYNVSDQADLVNDLGNKGYLVFGLILFVWELLPTTLLVGFFRVHRPPQDLSTSHILNGQVFASRSYFFDRAGHCEDEGCSWEHSRGESTRCQDQAATTTVSTPPHRRDPPPSPTEYPGPSPPHPRPLCQVCLPLLAQDPGGRGYPLLWPAPCCSCHSELVPSP
What is the function of this protein?
May activate Wnt/beta-catenin signaling to modulate epithelial cell function.
What are the official names of this protein?
Integral membrane protein GPR137, Transmembrane 7 superfamily member 1-like 1 protein.
What is the protein family that this protein belongs to?
Belongs to the GPR137 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.