PharMolix/UniProtQA huggingface dataset:
Protein: THYX_BPML5
Sequence: MKAKLIAATEIDPGALRDIGFEVDDFEESKDEDPYFGDFDADELAEFAGRNCYRSFHRPNPATAENEDYLNHIIDLGHESVFEHASATFYIEASRSVLTELERHRHLSFSVVSQRYVDPTDLGIHLPPALFKLHPDDRDDLVHIMESVSSEIDAVYEHIVNRLADRGLPRKQAREAARAVLPNMTNSPMVVTGNHRAWRYVIKARWHEAADAEIRELAGELLRQLRQIAPNTYQDIPDVPYSY
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Probable flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Gp48.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: GCH4_SYNAS
Sequence: MIDIQNLEDHRKINIQKVGVKGINYPIVVLDKAKGTQHVNASINMYVDLPHHFKGTHMSRFIEVLNEFRGEINIRTFHTILEKVRDKLKAESAHMEITFPYFIEKTAPVSGAKSLMDYICAFSGMNAENKKDFLVGVVVPVTTVCPCSKEISCMGAHNQRSHVTVKVRFKKFFWLEDIIRLVETSASGEVYSLLKRVDEKYVTEQGYANPMFVEDVVRNVAERLNENSNLTWYSVEAENFESIHNHNAYAYVEKE
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: NPFF2_RAT
Sequence: MGKRWDSNSSGSWDHIWSGNDTQHPWYSDINITYMNYYLHQPHVTAVFISSYFLIFFLCMVGNTVVCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAIMLHVQEEKYYRVRLSSHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLAPLSLIVIMYARIGASLFKTSAHSTGKQRLEQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYADLSPNKLRVINIYVYPFAHWLAFCNSSVNPIIYGFFNENFRSGFQDAFQFCQKKVKPQEAYGLRAKRNLDINTSGLLVHEPASQNPSGENLGCRKSADNPTQESLMEETGEATNSTET
What is the function of this protein?
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides.  Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Neuropeptide FF receptor 2, G-protein coupled receptor 74, Neuropeptide G-protein coupled receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSPA_STAAM
Sequence: MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIKKGGNLKPLEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQNIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDNPNNPDEPNNPDNPNNPDNPDNGDNNNSDNPDAA
What is the function of this protein?
Preferentially cleaves peptide bonds on the carboxyl-terminal side of aspartate and glutamate.  Along with other extracellular proteases it is involved in colonization and infection of human tissues.  Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB.  It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells.  May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM.  May be involved in the stability of secreted lipases (By similarity).
What are the official names of this protein?
Glutamyl endopeptidase, Endoproteinase Glu-C, Staphylococcal serine proteinase, V8 protease, V8 proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: NHAA1_BRUA4
Sequence: MNHSPNQSRPVSIMRRFLDSESAGGVSLMVAAALALIVANSPFSQAYFDILHTHIGPLSLTDWINDALMAVFFLLVGLEIKREFLDGQLASWPNRMLPGIAAAGGVILPAIIFTAFNWHDPAKVRGWAVPSATDIAFALGVLSLLGSRVPSSLKVFLATLAILDDLAAVVIIAIFYTAEISMPYLGGAFAAAIVLFVMNRMGVMKLLPYLIGGAALWFFVLNSGVHATVAGVVTALMIPLKAAPGRPDDMTSPLHVLEHALAKPVAFIIVPIFGFANAGISFAGLDASVMRDTLTLGIMLGLFIGKQLGVFGAAWLAIKTGLAQKPLGATWIQLYGVAVLCGIGFTMSIFIGLLSFPSDLMQAETKIGVLAGSGLSAICGYILLRLVTKPKNT
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KDGT_ECO57
Sequence: MQIKRLIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENV_SFV1
Sequence: MAPPMTLEQWLLWKKMSQAHQALENVTTLTEEQKQQVIIDIQHEDVVPTRMDKLKYLAYSCCATSTRVLCWIVLVCVLLLVVFISCFVTMSRIQWNKDIAVFGPVIDWNVSQQAVIQQIRAKRLARSIRVEHATETYVEVNMTSIPQGVLYVPHPEPIILKERILGLSQVMMINSENIANTANLTQETKVLLADMINEEMNDLANQMIDFEIPLGDPRDQKQYQHQKCFQEFAHCYLVKYKTTKGWPSSTVIADQCPLPGNHPTVQYAHQNIWDYYVPFEQIRPEGWNSKSYYEDARIGGFYIPKWLRNNSYTHVLFCSDQIYGKWYNIDLTAQERENLLVRKLINLAKGNSSQLKDRAMPAEWDKQGKADLFRQINTLDVCNRPEMVFLLNSSYYEFSLWEGDCGFTRQNVTQANSLCKDFYNNSKWQKLHPYSCRFWRYKQEKEETKCSNGEKKKCLYYPQWDTPEALYDFGFLAYLNSFPSPICIKNQTIREPEYKISSLYLECMNASDRHGIDSALLALKTFLNFTGQSVNEMPLARAFVGLTDPKFPPTYPNITRESSGCNNNKRKRRSVNNYERLRSMGYALTGAVQTLSQISDINDERLQHGVYLLRDHVVTLMEAALHDVSIMEGMLAIQHVHTHLNHLKTMLLMRKIDWTFIRSDWIQQQLQKTDDEMKLIRRTARSLVYYVTQTSSSPTATSWEIGIYYEIVIPKHIYLNNWQVINVGHLLESAGHLTHVKVKHPYEIINKECSDTQYLHLEECIREDYVICDIVQIVQPCGNATELSDCPVTALKVKTPYIQVSPLKNGSYLVLSSTKDCSIPAYVPSVVTVNETVKCFGVEFHKPLYAETKTSYEPQVPHLKLRLPHLTGIIASLQSLEIEVTSTQENIKDQIERAKAQLLRLDIHEGDFPDWLKQVASATRDVWPAAASFIQGVGNFLSNTAQGIFGSAVSLLFYAKPILIGIGVILLIALLFKIISWLPGKPKKN
What is the function of this protein?
The leader peptide is a component of released, infectious virions and is required for particle budding.
What are the official names of this protein?
Envelope glycoprotein gp130, Env polyprotein.
What are the subcellular locations of this protein?
[Envelope glycoprotein gp130]: Host endoplasmic reticulum membrane. Note=The polyprotein has a highly unusual biosynthesis for a retroviral glycoprotein. It is translated as a full- length precursor protein into the rough endoplasmic reticulum and initially has a type III protein configuration with both its N and C- termini located intracytoplasmically (By similarity). SUBCELLULAR LOCATION: [Leader peptide]: Virion membrane; Single-pass type II membrane protein. Host endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Its N-terminus is located inside the viral particle. SUBCELLULAR LOCATION: [Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM.
Protein: PA2B8_AUSSU
Sequence: MYPAHLLVLLAVCVSLLGAASIPPQPLNLVQFSYLIQCANHGSRATWHYTDYGCYCGKGGSGTPVDELDRCCKTHDDCYTEAGKKGCYPKLTLYSWKCTGKAPTCNSKTGCKRTVCDCDATAAKCFAKAPYNNKNYNIDTKKRCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits collagen-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Basic phospholipase A2 S10-58F, svPLA2, ASPLA8, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR7_TRIL1
Sequence: MSQPVKQTDFPGLKLVNRGKVRDIYDLGDALLMVTSDRISAFDVIMNEPIPDKGKVLTQISKFWFSQMEDIIPNHIISTDVADYPAACQPYAEVLAGRSMLVKKAEPLAAECIVRGYVSGSGWKDYKATGSICGIKLPEGLKESDRLAEPIFTPSTKAELGTHDENISFDEMVKVCGKELAEQAREATIRIYCRAREIADQKGIIIADTKFEFGVYEGKLIIIDECLTPDSSRFWPKDQYQPGGPQPSFDKQFLRDYLETLDWGKTAPAPPLPEEIVTKTGEKYKEALFKLAGITV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RL11_SYNP2
Sequence: MAKKVVTVIKLALPAGKANPAPPVGPALGQHGVNIMAFCKEYNAKTSDQAGMIIPVEISVYEDRSFTFILKTPPASVLIRKAAGVEKGSAQPNKQKAGSISRAQLQEIAQTKMPDLNANDIEAAMNIVAGTARNMGITVTD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SERB_ECOLI
Sequence: MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLGKIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEMVAEVTERAMRGELDFTASLRSRVATLKGADANILQQVRENLPLMPGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKLRLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGANDLPMIKAAGLGIAYHAKPKVNEKAEVTIRHADLMGVFCILSGSLNQK
What is the function of this protein?
Catalyzes the dephosphorylation of phosphoserine (P-Ser).  Also catalyzes the hydrolysis of phosphothreonine (P-Thr).
What are the official names of this protein?
Phosphoserine phosphatase, PSP, PSPase, O-phosphoserine phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. SerB family.
Protein: LPW_ECOLI
Sequence: MKAIFVLKGWWRTS
What is the function of this protein?
This protein is involved in control of the biosynthesis of tryptophan.
What are the official names of this protein?
trp operon leader peptide.
Protein: SKP1_RAT
Sequence: MPTIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
What is the function of this protein?
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.  In the SCF complex, serves as an adapter that links the F-box protein to CUL1.  The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.  SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling.  SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA.  SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2.  SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition.  SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1.  SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.  SCF(FBXW2) directs ubiquitination of GCM1.  SCF(FBXO32) directs ubiquitination of MYOD1.  SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5.  SCF(FBXO33) directs ubiquitination of YBX1.  SCF(FBXO11) directs ubiquitination of BCL6 and DTL but does not seem to direct ubiquitination of TP53.  SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription.  SCF(CCNF) directs ubiquitination of CCP110.  SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2.  SCF(FBXO9) directs ubiquitination of TTI1 and TELO2.  SCF(FBXO10) direct ubiquitination of BCL2.
What are the official names of this protein?
S-phase kinase-associated protein 1, Cyclin-A/CDK2-associated protein p19, S-phase kinase-associated protein 1A, p19A, p19skp1.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
Protein: BGAL_BIFLI
Sequence: MEHRAFKWPQPLAGNKPRIWYVGDYNPDQWPEEVWDEDVALMQQAGVNLVSVAIFSWAKLEPEEGVYDFDWLDRVIDKLGKAGIAVDLASGTASPPMWMTQAHPEILWVDYRGDVCQPGARQHWRATSPVFLDYALNLCRKMAEHYKDNPYVVSWHVSNEYGCHNRFDYSEDAERAFQKWCEKKYGTIDAVNDAWGTAFWAQRMNNFSEIIPPRFIGDGNFMNPGKLLDWKRFSSDALLDFYKAERDALLEIAPKPQTTNFMVSAGCTVLDYDKWGHDVDFVSNDHYFSPGEAHFDEMAYAACLTDGIARKNPWFLMEHSTSAVNWRPTNYRLEPGELVRDSLAHLAMGADAICYFQWRQSKAGAEKWHSAMVPHAGPDSQIFRDVCELGADLNKLADEGLLSTKLVKSKVAVVFDYESQWATEHTATPTQEVRHWTEPLDWFRALADNGLTADVVPVRGPWDEYEAVVLPSLAILSEQTTRRVREYVANGGKLFVTYYTGLVDDRDHVWLGGYPGSIRDVVGVRVEEFAPMGTDAPGTMDHLDLDNGTVAHDFADVITSVADTAHVVASFKADKWTGFDGAPAITVNDFGDGKAAYVGARLGREGLAKSLPALLEELGIETSAEDDRGEVVRVERADETGENHFVFLFNRTHDVAVVDVEGEPLVASLAQVNESEHTAAIQPNGVLVVKL
What is the function of this protein?
Specific for beta-D-anomer-linked galactoside substrates.  Hydrolyzes o-nitrophenyl-beta-D-galactopyranoside (ONPG), chromogen 5-bromo-4-chloro-3-indolyl-beta-D-galactopyranoside (X-gal) and to a lesser extent lactose.  Hydrolyzes p-nitrophenyl-beta-D-galacturonide very slightly.  Does not hydrolyze maltose, sucrose, raffinose or melibiose.  Has some transgalactosylation activity yielding galacto-oligosaccharides (GaOS), including O-beta-D-galactopyranosyl-(1,3)-O-beta-D-galactopyranosyl-(1-4)-D-glucopyranose.
What are the official names of this protein?
Beta-galactosidase III, Beta-gal.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 42 family.
Protein: VG40_BPML5
Sequence: MDEDDWDDYDYGTYECGCCTCCGCTCYYDEWDEEDDL
What are the official names of this protein?
Gene 40 protein, Gp40.
Protein: PNCB_BRADU
Sequence: MTVTDIASRTYNHSWRLDPIIRSLLDTDFYKLLMLQMIREDYSNQQVTFSVINRSRHVRLAEIIDEGELRAQLDHARTIRFTKKELIWLAGNTFYGKTHMFSADFIRWLAEFRLPEYELRKVEGQYELHFHGPWTHTTMWEIPALAILNELRSRAAIKGRGRFELDVLYARAKAKLWTKVERLRKLENLRLSDFGTRRRHGFLWQRWCVEAVKEGLGPSFIGTSNVLLAMDNDLEAIGTNAHELPMVAAGLAKDDEELRWAPYRILDQWRQTYGGNLLIALPDAFGTKAFLRDAPEWVADWTGFRPDSAPPIQAGEEIIAWWEKKGRNPRDKLLVFSDAMDVGSIEETYHHFTGRVRLSFGWGTNLTNDFVGCAPDGSFNLDPISLVCKVSSVDGHPAVKLSDNPEKATGLPSEIERYLRVFGDVGRVRKPVLV
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: HTPG_IDILO
Sequence: MAEAGQMEKHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFKALSDNSLYGDDSDLHVRVSVDKDSRTITISDNGVGMTRDDVMNNLGTIAKSGTAEFFGQLSGDEAKDSKLIGQFGVGFYSAFIVADEVTVRTRSALDKDARGVEWRSQGEGDFEIADIDKARRGTDIILHLKDDADEFLDENRLRGIINKYSEHLSIPVQMWKEPVPESEDDEGNKVEGQPGEWETVNSGQALWTREKSDITDEEYKEFYKTVAHDFDEPLLWSHNKVEGTTEYTNLLYIPKRAPWDLWNREQQHGVKLYVKRVFIMDDAEQLMPTYLRFVRGLVDSNDLPLNVSREILQDNKITRAMRNGSTKKVLQMLKKLAKDDKEQYQQFWDTFGNVLKEGPAEDHTNRERIAELLRFASTHNDGAVQSVSLDDYIERMKEGQDKIFYIVADSYEAARNNPALEIFNKKGIEVLLLSERIDEWLMSHLTEFKEKQLQSVTRGDLDLGELDDEEDKAEQEKAEEAFKENLERFEKALGDKVKKVRVTNRLTNSPACIITDDNDMSTQMAKLMEAAGQAVPETKYIFEVNPEHPLVQRMLTKEDDTFKEWAEVLLDQATLAERGNLKDPASFVTRLNKLMLNA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_PSELT
Sequence: MILVKKIIDKLRPVVIDILSQLGLELFDITLRRERRKLVLRVVIDDPENYVSIRQCEIVSSQIGNYLDEADLIDSSYILEVSSPGLDRPLREMKDYNRFVGRLAKIWLKDGKVLVGNIKETTENTVSIELKNGEIITFSFDQIKKGKLEIDF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMR1_CANGA
Sequence: MVAELTEFQKKRLENIKRNNDLLKKLQLQGTANKIKREAGVDTVSRHEERLKKKKKIVNAKKQSEKEASPKTAMPTRRSRRLMGQQVKNEEGIPNVSDTQLLKMNRNKELEDLKDIKETAVIGDVKLSDLIKTEEGSNEDELLAKFKQFANKNFSSGDFFDIIKKRQKETENDSDLTKMQEDFDLHMYDVFQPNEIKITNERITSMFFHPSTDKKLIVGGDTSGTVGLWNVRDEPLAENGEDDLVEPDITKVKFFTKNVGKIECFPTDTSTLLITSYDGSIRTLGLKDLKSADIMTLRNSYEEPLGISDCQFSYDNSQVLFLTTLGGEFTQLDLRAKPTETKFWRLSDKKIGSMAINPQRPYEIATGSLDRTLRIWDVRKTVETPEWSQYEDYHSHEIVSTFDSRLSVSAVSYSPTDGTLVCNGYDDTIRLFDVNGELPEDLDEKNKTVLKHNCQSGRWTSILKARFKPDQNVFAIANMGRAIDIYNSSGQQLAHLTTATVPAVLGWHPLKNWIAGGNSSGKVFLFTDELNTSK
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein CMR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: KARG_CARMA
Sequence: MADAATITKLEEGFKKLEAATDCKSLLKKYLTKSVFDQLKAKKTSLGATLLDVIQSGVENLDSGVGVYAPDAEAYTLFSPLFDPIIEDYHKGFKQTDKHPNKDFGDVNQFVNVDPDGKFVISTRVRCGRSMEGYPFNPCLTEAQYKEMESKVSSTLSNLEGELKGTYHALTGMTKDVQQKLIDDHFLFKEGDRFLQAANACRYWPTGRGIYHNDNKTFLVWCNEEDHLRIISMQMGGDLGQVYRRLVTAVNDIEKRVPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANRDKLEEVAGKYSLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: MATK_TRISM
Sequence: MKEYRVYLERARSRQQDFLYPLIFREYIYGLAYSHIDRSIFVENGGYDNKYSLLNVKRLITQMYQQNHLIISTNDSNKNPFLGYNKNFYSQIIAEGFAIVVEIPFFLQLSSSLEEAEIIKSYKNVRSIHSIFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDAPFFHLLRLFLYDFCNWNCFIPTKKSISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSSHLRLKSFSVFNERIFFYAKREHLVEVFSKDFSYTLPFFKDPNIHYVRYQGKCILASKNGPFLMNKWKHYFIHLWQCFFDVWSQPRTININQLSEHSIQLLGYFSNVRLNRSVVRSQMLQNTFLIEIVSKKLDIIVPIIPIIRSLAKAKFCNVLGHPISKPVWADSSDFDIIERFLRICSNLCHYYHGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLQTSGSEELLEEFFTEEEEILPWNFQILSLICHSKSFTSHGFHSNRIWYLDILFSNDLE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LIPA_KLULA
Sequence: MLKPGIRSVQKRFITETVVRSTQPSVSRRRKTTHFTDKLNKGPSFEDFVNGNAQKFTLDPLEKARQNSEEVQRLPTWLKVPIAKGSNFHKLKNDVKELKLSTVCEEAKCPNIGECWGGGDKSKATATIMLLGDTCTRGCRFCSVKTNRKPSAPDPTEPENTAEAISRWGLGYVVLTTVDRDDLVDGGAYHLAETVQKIKQKAPNILVETLSGDFRGDLEMVKVMALSGLDVYAHNMETVEALTPHVRDRRATYRQSLSVLECAKKTVPTLVTKTSVMLGLGETDEQVLQTMKDLRAIGCDVITFGQYMRPTKRHMKVVEYVTPEKFDYWKQKALELGFLYCASGPLVRSSYKAGESFIENVLRGRSRARI
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RNC_VIBVY
Sequence: MNSPIEKLTRQLGYQFQDDELLNLALTHRSANSKHNERLEFLGDSILSFVIADELYHRFPKVNEGDMSRMRATLVRGNTLAELGREFGLGDYLKLGPGELKSGGFRRDSILADAVEAIIGAVYLDSDLEVVRGIVLNWYASRLEAIKPGVSQKDPKTRLQEFLQGRRKPLPVYTVTNIKGEAHNQEFTVECDIAGMDKPVVGRGTSRRKAEQAAAELALEQLTNG
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX41_HUMAN
Sequence: MLATRVFSLVGKRAISTSVCVRAHESVVKSEDFSLPAYMDRRDHPLPEVAHVKHLSASQKALKEKEKASWSSLSMDEKVELYRIKFKESFAEMNRGSNEWKTVVGGAMFFIGFTALVIMWQKHYVYGPLPQSFDKEWVAKQTKRMLDMKVNPIQGLASKWDYEKNEWKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ATPE_DEHMB
Sequence: MAKLKLDIVTAERSVFSEEVDVVVAPGIEGEMAILPHHAPLMTALQAGELKAKIGTEEYSLVVSGGFLEVRPDRVVVLADSAERAEEIDIARAIEAKKRAEASMADKYVPGMLAAETEASLRRAMVRLKVAEKRRKHPQV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PDXJ_COXBN
Sequence: MVRLGVNIDHIATLRQARGVDYPDPVEAAMMAIEAGADGITLHLREDRRHIQDDDVRNLKRKLTVPMNLEMATAEDIIQFAEEIKPEHCCLVPEKREELTTEGGLDVAGQQNTLKKVCARLAKVGIEVSLFIDPEEKQIDAAKAAGAPVIEIHTGHYANAKTDHEHNQQLKRIADAAAYADSLGLTVNAGHGLTIHNVQSIAAIPVINELNIGHSIISRGVLIGLAEAVKEMKTLIAGAQ
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.