PharMolix/UniProtQA huggingface dataset:
Protein: HEMH_PSEF5
Sequence: MTDHALLLVNLGSPASTSVADVRSYLNQFLMDPYVIDLPWPVRRLLVSLILIKRPEQSAHAYASIWWEEGSPLVVLSRRLQKVMSEQWKQGPVELAMRYGEPSIESVLLKLVAQGQRKITLAPLYPQFADSTVTTVVEEARRVVREHKLDVQFSVLQPFYDQPEYIEALEASTRPHLQQPFDHLLLSFHGLPERHLNKLNPGHSLDGAGDCCAESSPQVLANCYRGQCFRTARAFAQQMGLADGQWSVSFQSRLGRAKWIEPYTEARLDELGKQGVKKLLVMCPAFVADCIETLEEIGDRGREQFREAGGEELVLIPCLNDDPQWAKALNALCERAPLAL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCNC_THITI
Sequence: MSADHDHDHDHDHDHKPAPMVEEVSDFEILEMAVRELAIEKGLFSAEDHRVWKDYVHTLGPLPAARLVAKAWLDPEYKKLCIEDGVEASKAVGVNWVTSPPTQFGTPSDYCNLRVLADSPTLKHVVVCTLCSCYPRPILGQSPEWYRSPNYRRRLVRWPRQVLAEFGLQLPSEVQIRVADSNQKTRYIVMPVRPEGTDGWTEDQLAEIVTRDCLIGVAVPKPGITVNAKRPVLKANRPVHHDH
What is the function of this protein?
Involved in the degradation of thiocyanate.
What are the official names of this protein?
Thiocyanate hydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the nitrile hydratase subunit alpha family.
Protein: ARGR_BIFLS
Sequence: MSETGPSLQRPATRAARLSAIEQALATHIITSQSQLSKILIDEGIAVTQATLSRDLDEMHAVKTRLKDGTVAYTVGRSAVASEGEDVGERGEAQMSRVLNGLVTSVAAAGNLVVVHTPSGAAQYVASVIDRQPIEGVLGTIAGDDTVMVICTNDDTAVSRSDWLLSLASK
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATF_NEUCR
Sequence: MATSQADARDRQFLAVIGDEDSVTGLLLAGIGHVTAPPDSQKNFLVVDNKTDNAAIEAAFDRFTTERKDIGIVLINQHIADRIRHRVDTHTAAFPTVLEIPSKDHPYDPEKDSVLRRVRRLFGE
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit F, V-ATPase subunit F, V-ATPase 14 kDa subunit, Vacuolar proton pump subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NS1_INBHT
Sequence: MADHMNTTQIEVGPGATNDTINFGAGILECYERLSWQRALDYPGQDRLNRLKRKLESRIKTHNKSEPEGTRMSLEERKAIGVKMMKVLLFMNPSAGIEGFEPYCMKNSSNSNCPNYNWTDYPPTPGRCLDDIEEEPEDVDDPTEIVLRDMNNKDARQKIKEEVNTQKEGKFRLTIKRDIRNVLSLRVLVNGTFLKHPNGYKTLSTLHRLNAYDQSGRLVAKLVATDDLTVEDEEDGHRILNSLFERLNEGHSKPIRAAETAVGVLSQFGQEHRLSPEEGDN
What is the function of this protein?
Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins.  Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response.  Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR.  Also binds poly(A) and U6 snRNA.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza B viruses NS1 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RL35_CORU7
Sequence: MKQKTHKGTAKRIKVTGSGKLRRERAYRRHLLEGKPSTRTRRLKGTTDVSAADNKRMKRLLGKA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: FABV_SHESW
Sequence: MIIKPKIRGFICTTTHPVGCEANVQEQITFTKNKGKIANGPKKVLVVGSSSGYGLSSRIAAAFGCDAATIGVFFEKPGTETKPGTAGWYNSAAFDKFAKAEGLYSKSINCDAFSHEAKQKVIELIKQDLGEIDMVVYSLASPVRRLPDSGEVIRSALKPIGETYTATAVDTNKDCIIEATVEPATEQEIADTVTVMGGQDWELWIKALSEAGVLANNCKTVAYSYIGTELTWPIYWHGALGKAKMDLDRAAKALNDQLSATGGSANVAVLKSVVTQASSAIPVMPLYIAMVFKKMRQEGLHEGCMEQIYRMFSERLYRTDGAKPETDSDNRLRLDDWELRDDIQQHCRDLWPQVTTENLSELTDYREYKAEFIKLFGFGIEGIDYDADVNPYVEFDVIELQ
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: TDH_FRATT
Sequence: MKALAKLKKQPGIWIINDAPIPEYGYNDVLIKIKKTAICGTDLHIYNWDKWSQNTIPVPMITGHEFAGEVVAKGDGVTSVDIGDRVSGEGHLVCGQCRNCRAGKRHLCRKTIGIGVNVQGAFAEYLVMPAVNVFKIPDSISDDIASTFDPMGNAIHTALSFNLTGEDVLITGAGPIGLMAVKIARFCGARRIVITDINEYRLQMARDFGATVALNVAPFKNQDELVKQMRKVMSDIGMTEGFDVGLEMSGINSAISMMLDVMNHGGKLSLLGISAGDISVDWGAILFKGLTLKGIYGREMFETWYLMTSMLQAGMDMNPIITHRLHIDEFQKGFEIMKSGQCGKVILDWSS
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_ECO27
Sequence: MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELLETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQEDMMRLLRGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: RL32_BACAC
Sequence: MAVPFRRTSKTVKRKRRTHFKLSVPGMVECPSCGEAKLAHRVCKACGTYKGKEVISK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: EIF3L_ASPFU
Sequence: MSYEERVNAHPNLGDESDVEEEALVNDYREQVNFDDGMSELDRTTSLGTGSQTQDLQAQLAAAATPLEYQATLETKFASYDNYCSLFHYILNSEGPVELEVPSYYWAWDVIDEFIYQFESFCRYRNRVARSGSNEEEAQLLRENPNTWGCYSVLNVLYSLIQKSQINEQLAAIKRGEDPLAFAGEYGSRPLYKMLGYFSIIGLLRVHCLLGDFSLALKTLDDIEMNKKAMFARVMAAHFTTYYYVGFSYMMMRRYGDAIRMFSHILVYVSRTKNFQKGGNSYDAIAKKNDQMYALIAICVALHPTRLDDTIHSALREKYGEQLLRLQHGGPDALPLFEELFRSACPKFISPTPPDFDNPALNIDPVDHHTAIFMDEVKNTLYNPTIRSYLKLYTTMDLKKLAGFLEVQPEVLRSWLLVNKQRSRQVRWVEGGLLEGEVVSANDLDYALENDLIHVSETKAGRRLVDWYLRNLARVY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_BACC2
Sequence: MFQVQKELAGHEVVIVALFEEEKMSSFVQELDKAFEGQLQVLLEEKELSTKKKAISKVHSLGKTNVKRYYFVGLGKKESYTTETLRAALGKAFKTLQVAKVQDAAILLDSFVTEKLDAIDVAHIAAEVQGLGTYELQTYKSDKKDREELEKFTAITAEDAQEIEAALTVGYVHGRATNSARTLVNMPPNVLTATKLAEYAVELAEKYDMDYKVLEKEEMEDLGMGALLAVNQGSVEPPKMIALIYKGKEEWTDVIGFVGKGITYDTGGYSLKPREGMVGMKGDMGGAAAVLGAMEIIGELRPEQNVIAVIPSTDNVVSGTAFKPDDVITSMSGKTIEVLNTDAEGRLALADGITYAKKLGANYLVDVATLTGGVIVALGNYTTGAMTNNEELFEQVLEASMETDEPIWQLPIFDRDKERVRNSKFADLNNSPGREGHAVMAGTFLGEFAEDTPWVHLDIAGTSETKGAHDLGPAGATGAMVRTLATLVERFGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_HAEDU
Sequence: MELVFIRHGFSEWNAKNLFTGWRDVNLTERGVEEAKAAGQKLLAAGYEFDIAFTSVLTRAIKTCNIVLEESNQLWIPQVKHWRLNERHYGELQGLDKKATAEKYGDEQVHIWRRSYDTLPPLLAPSDPNSAHNDRRYAHLPKEVVPNGENLKVTLERVLPFWEDQIAPALLSGKRVLVTAHGNSLRALAKHIIGISDAEIMDFEIPTGQPLVLKLDSKLNFIEKFYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: AMEL_MONDO
Sequence: IPLPPHPGHPGYINFSYEVLTPLKWYQSMMRHEYPSYGYEPMGGWLHHQIIPVLSQQHSPSHSLPPQHHIPIMAAQQPAPPQQPVMPVPGQHPMAPTQHHQPNLPQPGQQPYQPQPAQQPQPHQPIQPIQPIQPIQPMQPMQPMQPMQPMQPMQPQTPVHAVRPLPPQPPLPPMFPMQPMSPMLPDMEAWPATDKTKREEVD
What is the function of this protein?
Plays a role in the biomineralization of teeth.  Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development.  Thought to play a major role in the structural organization and mineralization of developing enamel.
What are the official names of this protein?
Amelogenin.
What is the protein family that this protein belongs to?
Belongs to the amelogenin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CH60_BUCMP
Sequence: MAAKDVKFGNEARIKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPSITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATLLAQSIVNEGLKAVAAGMNPMDLKRGIDKAVISAVEELKNLSVPCSDSKAITQVGTISANADEKVGALIAEAMEKVGNDGVITVEEGTGLQNELEVVKGMQFDRGYLSPYFINKPETGIVELENPYILVADKKISNVREMLPILESVAKSGKPLLIISEDLEGEALATLVVNSMRGIVKVAAVKAPGFGDRRKAMLQDISILTGGSVISEELAMELEKSTLEDLGQAKRVVISKDTTTIIGGVGEKHTIQSRISQIRQEIQEATSDYDKEKLNERLAKLSGGVAVLKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRVAGKTSNLRGQNEDQNVGIRVALRAMEAPLRQIVSNSGEEPSVVTNNVKDGKGNYGYNAATDEYGDMIDFGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKEDKSSDSNSSPAGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_BACSU
Sequence: MTHVRFDYSKALTFFNEHELTYLRDFVKTAHHNIHEKTGAGSDFLGWVDLPEHYDKEEFARIKKSAEKIKSDSDVLLVVGIGGSYLGARAAIEALNHAFYNTLPKAKRGNPQVIFIGNNISSSYMRDVMDLLEDVDFSINVISKSGTTTEPAIAFRIFRKLLEEKYGKEEAKARIYATTDKERGALKTLSNEEGFESFVIPDDVGGRYSVLTAVGLLPIAVSGVNIDDMMKGALDASKDFATSELEDNPAYQYAVVRNVLYNKGKTIEMLINYEPALQYFAEWWKQLFGESEGKDEKGIYPSSANYSTDLHSLGQYVQEGRRDLFETVLNVEKPKHELTIEEADNDLDGLNYLAGKTVDFVNKKAFQGTMLAHTDGNVPNLIVNIPELNAYTFGYLVYFFEKACAMSGYLLGVNPFDQPGVEAYKVNMFALLGKPGFEEKKAELEKRLED
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, Vegetative protein 54, VEG54.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LST8_MOUSE
Sequence: MNTTPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEITPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVSKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPESSITSAHIDPDASYMAAVNSAGNCYVWNLTGGIGDDVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSSNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFNDSVLG
What is the function of this protein?
Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals.  mTORC1 is activated in response to growth factors or amino acids.  Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1.  Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases.  Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis.  mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E).  mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation.  Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity.  In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity.  mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive.  mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.  mTORC2 promotes the serum-induced formation of stress-fibers or F-actin.  mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation.  mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'.  mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'.
What are the official names of this protein?
Target of rapamycin complex subunit LST8, TORC subunit LST8, G protein beta subunit-like, Protein GbetaL, Mammalian lethal with SEC13 protein 8, mLST8.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LST8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_PSEU2
Sequence: MNTPVGVAEIVLGPGEVVFQTRPTRLRTLLGSCVAITFWHPWRRIGGMCHFMLPGRIRRHQPLDGRYADEAMEILIRHALANGTLPEEYQVKLFGGGEMFPAHRHDPHMRNVADSNVHAALALAEQNRLKLMAQDLGSTGHRSIIFDLWDGNVWVRHQPMEAMEKDAKQKNQRTAGR
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: SUCC_DEIDV
Sequence: MKLHEYQGKEILRQFGVNVQDGKVARTPDEVRQIAREYGQPVVVKAQVHVGGRGKAGGVKFSPTEDKAFENGEKILGMDIKGLTVNKVLVTKAVDIDAGTEYYVGMIVDRNVQSFTLMASAEGGMEIEEVAAATPEKIIKHRVDPVTGLRPYEAREVAIRAGFKGNLNKIADMMVKMSEAALKRDAVLVEINPLFVGPDGVPLALDTKFEIDDNAMYRHQDLADWRELEAEHPLEIEASKYGFAYVKLDGNVGVLGNGAGIVMTSLDVVNRAGAKPANFLDIGGGAKAEVVYNAVKLVSKDSDVKAIFINIFGGITRADEVAKGVIQALKDGILTKPVRMRIAGTAEDEAKALLAEVNSPLIQMYPTMFEAADEAAKEANAAEAK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: LSPA_CHLAB
Sequence: MSSRSRSTFLAIACFVLIDWVTKLAVLLYLGNLPDANPILYQYSWGKLLFCICPTFNEGAAFGLFAKYKYFLFFIRITIILGILAFLFLRKKTSSPAIRFSLILLCSGAIGNVGDIVFYRHVVDFISIGYKRWFFPTFNFADIFISLGTLIFIYKLYFPTKQKIK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYL_BACC3
Sequence: MSFNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEIIDGKSERGGHPVERRPMRQWMLKITAYGDRLLEDLDELDWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKFTVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKTGVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVKGGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGKKGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPFQQLFNQGMILGENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLDRVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAYKAETLPKEYVEGFVKMIAPVAPHIGEELWSKLGYNETITYASWPTFDESKLVEDEVEIVVQVMGKVRAKLTMSKDASKDEMEKLALEAIQDQIEGKTVRKVIVVPGKLVNVVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_HYPNA
Sequence: MPLKSHEFTSESVAEGHPDKVADQISDAIVDLFLSKDPTSKVAVETLCTTNRVVLAGEVRTNNGSVVTPDEMNAAARAVVKKIGYEQDGFHWEKMAVENHVHGQSAEIAQGVEEGQGLFKEEGAGDQGIMFGYATDETPELMPATLVYSHQILQKLAELRHSGKNPQLEPDAKSQVTLQYEGSRPVGVNAVVVSHQHKAGVSQEELREVIRPVVKAVLPEGWFPPEEKFYVNPTGSFVIGGPDGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYATRYLAKNIVAAGLATRCTIQVSYAIGVAQPLSIYVDTHGTGQADEARIAKAVRELFDLSPKGIRTHLKLSNPIYGPTAAYGHFGRIPGEGGTFTWEKTDLAGELKRLVN
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME2_XANC8
Sequence: MNPQRRRRLWLVLALVLAGGLATTLVAMALQRNVAYLYTPAEVLRGEAGEHARFRLGGMVEKGSFRREAGSLEAHFRVTDGDAQLPVRYDRILPDLFREGQAVVATGRMQQGVFVAEDVLAKHDETYMPKEVADKMGSAHRKHQVAPAKVTQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE 2, Cytochrome c maturation protein E 2, Heme chaperone CcmE 2.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: NOL6_DROYA
Sequence: MLRNKRKAGKLVRAPQKAARIDSQANAHAEDHSDLEHSAPSTDDGFDEPKPTIAKKVSLSTAIPKKNKFKQRDDTKNVKPPTLEEMKELRDTQNLFHSNLFKLQVKEMLEELQLKQKYTDFIENWLESFTVFTRQLKDGLMERSHLEIPLKLSQKPTGFVFSKPTREPYLIGAAATGTLLGPKIVVDVALEMPKESLHKEDYLNLRYDQKRALYLTYVTERMKESPAYAQDQFNFNYYANNPLKPVLELTPGTKQVNKHLQVRLFITAPLSSFKPGRFVPWNNNIRPSYYGDEWDEKEPLPSTQHYNANVLFDLTLSENQTHLDKAFKGRRNFQDGLLLLKVWLRQRQLDIGYSGFGAHILSAFIVYLNTQRILHHSSSSYQVARTVWNQLANTDWTKGISLSLVPIQTEELNKFAEQYDVCFIDFTGQHNLCANIPLYLYQRVREEAKLAVELLNDMKLNSFPLIFMQKCPLYSRVDNILKISNYSCINQMLTLHSQPRFKYDFAKYGYPQLLQLLTELLKKGLAERVHSILPLETATPAWPVENKAPVIGNYIQLGLILQPEHAYEVLNKGPAANDDPEGAEEFRRFWGEKSNLRRFQDGSITEAVVWGSAQDSPAKKRLIVRQIVLHLLEHQLQLDSKDVQYIAGELDQVYKLSPWFKVNKLKTKLSLDQDTDAEALSPHAIRSYDELARQLHGLNDLPLEIVSISGVSPVFRYCEPQPVLPQARLVENRILTSSIQRVVIQLGQSGKWPNELSALRALKTAFLIEIGEKLEAQCHLHWMMSADGLLVLKQGYCFLIELAHNKELALLKQEVTERGITTYIDNAASRSLERQHYILPKVSGALHSLHQTYSAFGSTVLLAKRWLATQLLDDGLWPDMATELLVAHLFQQRYAPQPIEAPQTGFIRFLQLLAFSDFNGELFLLNFNNSWQEQQVADLEHNYRSNRQSYPPLAVATSYDMQHAGRLWTSEESPSQRVLGHVTRLARHALEIIETSLLSKDLRFVRPAQLFRASNEGYDLVIQFKPDLVPNSLSYDLGSPFVSFSQPNFNLTRAGSGDVARIVGLLRSAYSDFAAFFYNPHGGKELAIVWRPPTEFAAKPFKVTELQACSPCGNGRVQVIKETLVEDFKLLLKDFYLRIATPEELKREQREHQKPKRYFDAKQTEEKSTPKPKVRKANEKEAPPKKKRLIKSSALKALK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Nucleolar protein 6, Maternal transcript 89Ba.
What is the protein family that this protein belongs to?
Belongs to the NRAP family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ANXA2_MESAU
Sequence: STVHEILCKLSLEGDHSTPPSAYGSVKDALNIETAVKGVDEVTIVNILTNRQDIAFAYQRKELPSALKTPAQYDASELKGLGTDEDSLIEIICSRTNQELQEINRTDLEKDIISDTSGDFRKLMVALAKRAEDGSVIDYELIDQDARDLYDAGVKRWISIMTERSVCHLQKDKVLIRIMVSRSEVDMLSLYYYIQQDTK
What is the function of this protein?
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids.  It binds two calcium ions with high affinity (By similarity).
What are the official names of this protein?
Annexin A2, Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: RL3_SHESM
Sequence: MAIGLIGRKVGMTRIFTEDGVSIPVTVIEVAGNRVTQVKTLETDGYRALQVTTGTKKANRITKPEAGHFAKSGVEAGRGLWELRLADGEGEGIEVGAELNVGIFADVAKVDVTGQSKGKGFQGGVKRWNFRTQDMTHGNSLSHRSNGSIGQNQTPGRVFKGKKMSGHMGAERVTTQNLDVVRVDVERNLLLVKGAVPGATNGDLIIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RS16_GLOVI
Sequence: MKRIGAKKKPVYRIVVTDSRSRRDGAVIEEIGFYDPRANTEKGLPEVTLDVEAARRWLSHGARPSETVQGLLKRAQVYASPSSSTPDSD
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ROA1_XENLA
Sequence: MHKSEAPNEPEQLRKLFIGGLSFETTDESLREHFEQWGTLTDCVVMRDPNSKRSRGFGFVTYLSTDEVDAAMTARPHKVDGRVVEPKRAVSREDSSRPGAHLTVKKIFVGGIKEDTEEDHLREYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFEDHDSVDKIVIQKYHTVNNHNSQVRKALSKQEMASVSGSQRERGGSGNYGSRGGFGNDNFGGRGGNFGGNRGGGGGFGNRGYGGDGYNGDGQLWWQPSLLGWNRGYGAGQGGGYGAGQGGGYGGGGQGGGYGGNGGYDGYNGGGSGFSGSGGNFGSSGGYNDFGNYNSQSSSNFGPMKGGNYGGGRNSGPYGGGYGGGSASSSSGYGGGRRF
What is the function of this protein?
This protein is a component of ribonucleosomes.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoproteins A1 homolog, hnRNP A1, Helix-destabilizing protein, Single-strand-binding protein, hnRNP core protein A1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles continuously between the nucleus and the cytoplasm along with mRNA.