PharMolix/UniProtQA huggingface dataset:
Protein: MGRB_ECO55
Sequence: MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NQRD_CHLAB
Sequence: MAANKSYKSYFLDPLWNNNQPLIAILGICSALAVTTTVNTALTMGLAVSFVTGCSSFFVSLLRKVTPDSVRMITQLIIISLFVIVIDQFLKAFFFDISKTLSVFVGLIITNCIVMGRAESLARNVPPIPAFLDGFASGLGYGWVLVTVSIIREFFGFGTILGLQLIPKCFYASEAHPDGYENFGLMVLAPSAFFLLGIMIWGVNILRSKKERR
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WAC_MOUSE
Sequence: MVMYARKQQRLSDGCHDRRGDSQPFQALKYSSKSHPSSGDHRHEKMRDAADPSPPNKMLRRSNSPENKYSDSTGHNKAKNVHTQRVRERDGGTSYSPQENSHNHSALHSSNSHSSNPSNNPSKTSDAPYDSADDWSEHISSSGKKYYYNCRTEVSQWEKPKEWLEREQRQKEANKLAVNSFPKDRDYRREVMQATATSGFTSGMEDKHSSDASSLLPQNILSQTSRHNDKDYRLPRAETHSSSTPVQHPIKPVVHPTATPSTVPSSPFTLQSDHQPKKSFDANGASTLSKLPTPTASLPAQKTERKESAPGDKSISHSCTTPSTSSASGLNPTSAPPTSASAVPVSPVPQSTIPPLLQDPNLFRQLLPALQATLQLNNSNVDISKINEVLTAAVTQASLQSIIHKFLTAGPSAFNITSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPMKPLISTPPVSSQPKVSTPVVKQGPVSHSATQQPVTADKQQSHDPVSPRSLQRLSSQRSPSPGPNHTCSSNASTATVVPQNASARPACSLTPTLAAHFNDNLIKHVQGWPADHAEKQASRLREEAHNMGSVHMSEICTELKNLRSLVRVCEIQATLREQRILFLRQQIKELEKLKNQNSFMV
What is the function of this protein?
Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1).  Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription.  Regulates the cell-cycle checkpoint activation in response to DNA damage.  Positive regulator of amino acid starvation-induced autophagy.  Also acts as a negative regulator of basal autophagy.  Positively regulates MTOR activity by promoting, in an energy-dependent manner, the assembly of the TTT complex composed of TELO2, TTI1 and TTI2 and the RUVBL complex composed of RUVBL1 and RUVBL2 into the TTT-RUVBL complex.  This leads to the dimerization of the mTORC1 complex and its subsequent activation.  May negatively regulate the ubiquitin proteasome pathway.
What are the official names of this protein?
WW domain-containing adapter protein with coiled-coil.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus. Note=In distinct nuclear speckles. Colocalizes with pre-mRNA processing complexes.
Protein: ARGR_STRGG
Sequence: MTEAQEPEYGGPSVPQTRTARHRRIVDILNRQPVRSQSQLAKLLADDGLSVTQATLSRDLDELGAVKIRNTGGELIYAVPSEGGFRTPQAPLGGSAKEERMRRLSAELLISAEASANLVVLRTPPGAAQFLASAIDQAELHDILGTIAGDDTLMLISRDPSGGQALADHLLRLAQNDR
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCKB_MOUSE
Sequence: MEELVGLREGASKKPVPLQELWGPCPRIRRNIQGGLEWLKERLFRVGEDWYFLVALGVLMALISYAMNFTIGRVVRAHKWLYREIGDGHLLRYLSWTVYPVALLSFSSGFSQSITPSSGGSGIPEVKTILTGVVLEDYLDIKNFGAKVVGLSCTLATGSTIFLGKLGPFVHLSVMIAAYLGRVRTKTVGEPESKTKEMELLAAGAAVGVATVFAAPISGVLFSIEVMSSHFSVWDYWRGFFAATCGAFMFHLLAVFNNEQETITSIYKTSFPVDIPFDLPEIFFFVALGAICGILSCGYNYSQRTFLFFLKANGFTSKLLATSKPLYSALAAVVLASITYPPGVGHFMASRLSMSEHLETLFDNNSWALMTKNSSPPWAAEPDPQKLWLEWCHPQLTVFGTLVFFLVMKFWMLILATTIPIPAGYFLPIFIYGAVIGRLFGEVLSVAFPEGIVAGGRVNPIMPGAYALAGAAAFSGAVTHTLSTALLAFEVTGQLVHALPVLMAVLAANAISQSFQPSFYDGTIIVKKLPYLPWIRGRQIGSHSVTVGHFMNCALTTLAKDMPLEQVIQVVISTDVTQYPLVETTESQTLVGVVKRTHLVQALQTEPASWAPGQQPCLQDILANGCPTQPVTLQLSLETSLHETHNLFELLNLQTLFVTSRGRAVGSVSWVELKKAISTLTNPPAPK
What is the function of this protein?
Voltage-gated chloride channel.  Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.  May be important in urinary concentrating mechanisms.  May be the basolateral chloride channel mediating net chloride absorption in CTAL cells.
What are the official names of this protein?
Chloride channel protein ClC-Kb, Chloride channel Kb, ClC-K2.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. CLCNKB subfamily.
Protein: IF1_ALIB4
Sequence: MAKDDVIVVDGKVIEALPNAMFRVELDNGHVVLCHISGKMRMHYIKILPNDTVKVEITPYSLDKGRITHRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METC_YEAST
Sequence: MIDRTELSKFGITTQLSVIGRNPDEQSGFVNPPLYKGSTIILKKLSDLEQRKGRFYGTAGSPTIDNLENAWTHLTGGAGTVLSASGLGSISLALLALSKAGDHILMTDSVYVPTRMLCDGLLAKFGVETDYYDPSIGKDIEKLVKPNTTVIFLESPGSGTMEVQDIPALVSVAKKHGIKTILDNTWATPLFFDAHAHGIDISVEAGTKYLGGHSDLLIGLASANEECWPLLRSTYDAMAMLPGAEDCQLALRGMRTLHLRLKEVERKALDLAAWLGNRDEVEKVLHPAFEDCPGHEYWVRDYKGSSGLFSIVLKNGFTRAGLEKMVEGMKVLQLGFSWGG
What are the official names of this protein?
Putative cystathionine beta-lyase, CBL, Beta-cystathionase, Cysteine lyase, Cysteine-S-conjugate beta-lyase, Increased recombination centers protein 7.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
Protein: MIAB_CHESB
Sequence: MEQNLTTERSETSSSRAGTASRTDKKVFVKTYGCQMNVYDSQRMADALAAEGYRATDVIEDADLVLLNTCHIREKAAEKVYSELGRIRVLKEERAKQGRETVVGVAGCVAQAEGREILRRAPAVDLVIGPQTYHRLPSVVTRARAGEKIVETEYAVEDKFDHLPAPERTAVRSRGVTAFLTVQEGCDKFCTFCVVPYTRGAEVSRPVAQIVAEAERLAEAGVRELTLLGQNVNAWHGEGPDGREWGLGRLLFRLAEIPGLDRLRYTTSHPRDMDEELIAAHRDLIKLMPYLHLPVQAGSDRILKAMNRKHTAADYLRLIERIRAARPDIAMSGDFIVGFPGETDRDFEDTMRIVRDVNYAQAFSFKYSPRPGTPGADMHDQVPDAVKDERLQRLQALLAEQQRAFGESLVGTEIDLLLEKPGRQAGQLVGRSPWLQPVIVEENAGQIGDIVRVRITSSGGHSLFCEPAGTARVAL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_NATJA
Sequence: MTNIRKSHPLTKIINSSFIDLPTPSSISSWWNFGSLLGICLAVQILTGLFLAMHYTADTSTAFNSVTHICRDVNYGWILRYMHANGASMFFICLYLHVGRGLYYGSYTYTETWNVGIMLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISAMVMVHLLFLHETGSNNPTGIPSNMDMIPFHPYHTIKDILGLLLMLTALLVLVMFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIIPLLHTSKQRSMMFRPISQCLFWLLVADMLTLTWIGGQPVEHPYIIIGQLASIMYFSIILIFMPLASLAENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IF1_CLONN
Sequence: MSKDDVIEMQGTVLEALPNAMFQIQLESGQTILGHVSGKLRMNFIRILPGDKVTVELSPYDLSRGRITWRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F166C_HUMAN
Sequence: MASRSAGTLLTEFNAAYVPPGLMPGYQGHVPTVAFSFGAPYGTTTLKYFQDHRNRAMEKSHTPFSQGGHFPTIFSTNPNLLLMERASTRDRWLHKPSYTRFNLDSHRSTELTNFYQMVQQHRKYYQDKTGTVPRVPYFAMPVREPERYPLPTVLPPLCPKKKWHLLRLAPENLKTYQTFPSGKRVSPQERKKRDCYFEFRA
What are the official names of this protein?
Protein FAM166C, Family with sequence similarity 166 member C.
What is the protein family that this protein belongs to?
Belongs to the FAM166C family.
Protein: SM3L1_ARATH
Sequence: MRVLKYFRAPSSLRHRSSPMAQFLRRFSSSPMANEDEFQSPVEPSQQQSQDCVSESYLIGFVIANIVGLKYYSGRINGREMVGLVREPLNVYDNNAIRVLNTRSEQVGHIERTVAAVLAPMIDSHTIVVEGIVPNTRSNSNRYRIPCQIHVFAKLEASSTVKSTISRGGLVLISESDTSFGLSEAVVVKEQMGNGDKRSVDKIFKLVDENVKLMGKLVAAEPPREVIKSELFAHQKEGLGWLLHREKSGELPPFWEEKDGEFLNTLTNYRSDKRPDPLRGGVFADDMGLGKTLTLLSLIAFDRYGNASTSTPTEEPLDGEGDKIEKKGKKRGRGKSSESVTRKKLKTDDVVGMNVSQKTTLIVCPPSVISAWITQLEEHTVPGILKVYMYHGGERTDDVNELMKYDIVLTTYGTLAVEESWEDSPVKKMEWLRIILDEAHTIKNANAQQSRVVCKLKASRRWAVTGTPIQNGSFDLYSLMAFLRFEPFSIKSYWQSLIQRPLGQGNKKGLSRLQVLMATISLRRTKEKSLIGLPPKTVETCYVELSPEERQLYDHMEGEAKGVVQNLINNGSLMRNYSTVLSIILRLRQLCDDMSLCPPELRSFTTSTSVEDVTDKPELLQKLVAALQDGEDFDCPICISPPTNIIITRCAHIFCRACILQTLQRSKPLCPLCRGSLTQSDLYNAPPPPPDSSNTDGEDAKSSTKSSKVSALLSLLMASRQENPNTKSVVFSQFRKMLLLLETPLKAAGFTILRLDGAMTVKKRTQVIGEFGNPELTGPVVLLASLKASGTGINLTAASRVYLFDPWWNPAVEEQAMDRIHRIGQKQEVKMIRMIARNSIEERVLELQQKKKNLANEAFKRRQKKDEREVNVEDVVALMSL
What is the function of this protein?
Possesses intrinsic ATP-dependent nucleosome-remodeling activity.  This activity may be required for transcriptional activation or repression of specific target promoters (By similarity).
What are the official names of this protein?
Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1, SMARCA3-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPL_CAMJ8
Sequence: MKKVLFLLLACAAVAFAAETNAPVEQEAINVWIKAFSVLAAGLGLGVAALGGAIGMGNTAAATIAGTARNPGLGPKLMTTMFIALAMIEAQVIYALVIALIALYANPFIVLQ
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUDC_SALPC
Sequence: MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRERYYPQIAPCIIVAIRREDSILLAQHVRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIAIDPKELLEANWYHYDDLPLLPPPGTVARRLIEDTVAMCRAEYD
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: NDK_CAMJJ
Sequence: MEKTLSIIKPDAVKKGVIGKILDRFESNGLRIAAMKKVQLSKEQAENFYAVHKERPFFKDLVEFMISGPVVVSVLEGEGAVLKNRDLMGATNPKEAKAGTIRADFAESIDANAVHGSDSLENAKIEIEFFFKPNEIC
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_BORGP
Sequence: MKTAHWADFYAEKIKKEKGPKNIYTVASGITPSGTVHIGNFREVISVDLVARALKDSGSQVRFIYSWDNYDVFRKVPKNMPEQELLTTYLRQAITRVPDTRGYKTSYARANEIEFEKYLPIVGINPEFIDQSKKYTNSTYASQIKFALNHKKELAEALNEYRTSKLEENWYPISIFCTKCNRDTTTVNNYDNHYSVKYSCECGNQESLDIRTTWAIKLPWRIDWPMRWKYEKVDFEPAGKDHHSSGGSFDTSKNIVKIFQGSPPVTFQYDFISIKGRGGKISSSLGDVISLKDVLEIYTPEVTRFLFAATKPNTEFSISFDLDVIKIYEDYDRFERIYYGVEDIKEEKKRSFKRIYELSQPYMPSKRIPYQIGFRHLSVICQIFENNINKILNYLKNVQDDQKDKLINKIKCVINWIKDFAPEDFKFLLRSKFDNIEILKEDNKKAISELLDSLKKNFEVATEQDIQNEIYKISRENNIEPALFFKQIYKILIDKEKGPKLAGFIKIIGIDRFEKIVSKYI
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUA9_DICDI
Sequence: MLKNLSKGFPSLINKRSFSTINENPLTRIHHGSRTQTTGLVATVFGATGFTGRYLVQLLARTGIQVVVPYRCEDEGFRDLKVLGELGQIIPVRFDIRDSESIERAISHSNIVINMAGRDYETRNFSLDDINVHAASRIADLSKNVEKYIHVSTLRASEDSPSHFSRSKAIGEKLTREIIPNCTVVRPSIIFGDEDKFINKWSKVSQNWPFIPRYNQQHKIQPLHCYDLASGILSILETPGTSGKVYEFAGDEVFTWDEFLDMIIDGTAQYSKLNIPVSNDFMKFISEHLLERFARNPNFIKDQIDYHNQDMTTTVGALTLKDLNVTTTPIQEKLIRLSRMYRPGKFFNAIANPQNK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA9 subunit family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PSEI_CAMJE
Sequence: MQIGNFNTDKKVFIIAELSANHAGSLEMALKSIKAAKKAGADAIKIQTYTPDSLTLNSDKEDFIIKGGLWDKRKLYELYESAKTPYEWHSQIFETAQNEGILCFSSPFAKEDVEFLKRFDPIAYKIASFEANDENFVRLIAKEKKPTIVSTGIATEEELFKICEIFKEEKNPDLVFLKCTSTYPTAIEDMNLKGIVSLKEKFNVEVGLSDHSFGFLAPVMAVALGARVIEKHFMLDKSIESEDSKFSLDFDEFKAMVDAVRQAESALGDGKLDLDEKVLKNRVFARSLYASKDIKKGEMFSEENVKSVRPSFGLHPKFYQELLGKKASKDIKFGDALKQGDFQ
What is the function of this protein?
Catalyzes the fifth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin.  Catalyzes the condensation of phosphoenolpyruvate with 2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose, forming pseudaminic acid.
What are the official names of this protein?
Pseudaminic acid synthase, Pseudaminic acid biosynthesis protein I.
What is the protein family that this protein belongs to?
Belongs to the pseudaminic acid synthase family.
Protein: RISB_GEOSL
Sequence: MPRFIEGKLDATGLRFGIIVSRFNSFIGERLLEGALDALVRHGGDDGDIDVVRVPGAFEIPLTAQKLVQKGNYDAVICLGAVIRGSTPHFDYVAAEVSKGIAHVSLATGVPVVFGVLTTDTIEQAIERAGTKAGNKGFDAAVTAIETARLYRELR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RL14_SERP5
Sequence: MIQEQTMLTVADNSGARRVMCIKVLGGSHRRYAGIGDVIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: KMO_YEAST
Sequence: MSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISARGIDALKSIDPDACEHILQDMIPMKGRMIHDLKGRQESQLYGLHGEAINSINRSVLNNSLLDELEKSTTELKFGHKLVKIEWTDDKQICHFAIGEDLKTPHTEKYDFVIGCDGAYSATRSQMQRKVEMDFSQEYMNLRYIELYIPPTEEFKPNYGGNFAIAPDHLHIWPRHKFMLIALANSDGSFTSTFFGSKDQISDLITSKSRVREFLIENFPDIINIMDLDDAVKRFITYPKESLVCVNCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILMALLKKHSGDRSRAFTEYTQTRHKDLVSITELAKRNYKEMSHDVTSKRFLLRKKLDALFSIIMKDKWIPLYTMISFRSDISYSRALERAGKQTRILKFLESLTLGMLSIGGYKLFKFLTRERS
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Biosynthesis of nicotinic acid protein 4, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: RL331_LACP3
Sequence: MRNNIILGNNETGERIYLTSKNKRNTPDRLQLKKYSPKLRKRVVFTEVK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: DXR_BLOPB
Sequence: MQSLTILGSTGSIGKATLSVIQQHTDKFFVHALVAKNNVAIMTEQCIAMSPKYACMISEDAARILKKNLITAGKYDIEVLSGVMHACELASTNDVDMVMSAIVGIAGLKPTFSALRAGKKILLANKETLVTGGKLFMKEANRYRACILPIDSEHNAIFQNLPEICQKSLGNTSLSECGISRIVLTASGGIFFKTPQKQLTKITPEQACVHPNWSMGRKISVDSATMMNKGLEYIEARHLFNAKPSEIEILLHPQSIVHAMVYYSDGNVLAHLAPPDMRIPIAYAMAYPKRIGLKISSNIDIYYLNKLHFDQLDNCSYPCFQLAIDADNCSQSATIILNAANEIAVEAFLRKMISFTDIPDVIRRVLDAINLNDPNDIEDILYIDQKAREKAISICVI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: EF1A_HALS3
Sequence: MSDNRHQNLAVIGHVDHGKSTMVGRLLYETGSVPEHVIEQHKEEAEEKGKGGFEFAYVMDNLAEERERGVTIDIAHQEFTTDEYEFTIVDCPGHRDFVKNMITGASQADNAVLVVAADDGVAPQTREHVFLSRTLGIDELIVAVNKMDVVDYDESKYNEVVSGVKDLFGQVGFNPDDAKFIATSAFEGDNVSDHSDNTPWYDGPTLLEALNGLPVPQPPTDADLRLPIQDVYTISGIGTVPVGRIETGVMNTGDNVSFQPSDVGGEVKTIEMHHEEVPNAEPGDNVGFNVRGIGKDDIRRGDVCGPADDPPSVADTFQAQVVVMQHPSVITAGYTPVFHAHTAQVACTIESIDKKMDPASGETQEENPDFIQSGDAAVVTVRPQKPLSLEPSSEIPELGSFAVRDMGQTIAAGKVLDVDEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSL53_DICDI
Sequence: MTLFSSISSLSSSMTSSRSIFASFGSGTIMGSNSISCTVGSGSCGSGSGGCGDLTGGAKSSGGSCGGKGGSHNHGHGHGPHGQGGKGSGGSCSC
What are the official names of this protein?
HssA/B-like protein 53.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: HTPX_SHESR
Sequence: MKRIFLLIATNLAVLLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDSTERWLLETVARQAQQAGIKMPEVAIYQSPEMNAFATGPSKDNSLVAVSTGLLYGMSQDEVEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIINNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREYRADEGAARLAGKHKMIAALERLRQGPESSAMPAQMSAFGINGKRSMAELMMSHPPLEKRIAALQTR
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y438_BRUSU
Sequence: MTSSKTGQITIRSIGAGGDGVANLPDGQIYVPFTLPGEVVNVARDKNRATLMALLEASPERQNPACRHFEDCGGCALQHWQDEPYRLWKRELVVGALKGRGIDVEVAPLVACNPHTRRRAVFAARKTEKGVLLGFNRHQSHEIIDIVECPVTVPEIIARLDDLREVGALLAPGSGPFKLAATLTESGLDLAASGCGKLNDEQRRALTALVIKKDFARLSHEGEIIVEPKKPLIHFGKVPVPVPPGCFLQATAEAEETMAALVLAHLGKARRVADLFCGVGTFALRIAEKSAVHAVENDAAALAALDRGVRHVQGLKPVSIERRDLFRRPLMPKELLPYNAVVFDPPRAGAEEQALELAKSKVEKVVAISCNPVTLARDLAILQKGGYRIERVTPIDQFLWSAHVEAVAVLTKGRQ
What are the official names of this protein?
Uncharacterized RNA methyltransferase BR0438/BS1330_I0439.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: TRYT_CANLF
Sequence: MPSPLVLALALLGSLVPVSPAPGQALQRVGIVGGREAPGSKWPWQVSLRLKGQYWRHICGGSLIHPQWVLTAAHCVGPNVVCPEEIRVQLREQHLYYQDHLLPVNRIVMHPNYYTPENGADIALLELEDPVNVSAHVQPVTLPPALQTFPTGTPCWVTGWGDVHSGTPLPPPFPLKQVKVPIVENSMCDVQYHLGLSTGDGVRIVREDMLCAGNSKSDSCQGDSGGPLVCRVRGVWLQAGVVSWGEGCAQPNRPGIYTRVAYYLDWIHQYVPKEP
What is the function of this protein?
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.
What are the official names of this protein?
Tryptase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Tryptase subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Released from the secretory granules upon mast cell activation.