PharMolix/UniProtQA huggingface dataset:
Protein: SNRK_RAT
Sequence: MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQRDPKRRASLEEIESHPWLQGVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLLAERILREKQEKEIQTRSASPSNIKAQFRQSWPTKIDVPQDLEDDLTATPLSHATVPQSPARAGDSVLNGHRSKGLCDPAKKDELPELAGPALSTVPPASLKPAASGRKCLFRVEEDEEEDEEDKKPVSLSTQVVLRRKPSVTNRLTSRKSAPVLNQIFEEGESDDEFDMDENLPPKLSRLKMNIASPGTVHKRYHRRKSQGRGSSCSSSETSDDDSESRRRLDKDSGLAYSWHRRDSSEGPPGSEGDGGGQSKPSGGGGVDKASPGEQGTGGSGQGGSGGTPSGTAGSSRRCAGPDSSSSSPASAAPRGAELVQSLKLVSLCLGSQLHGAKYILDPQKALLSSVKVQERSTWKMCISAPGPGPSADLDPVRTKKLRNNVLQLPLCEKTISVNIQRSRKEGLLCASSPASCCHVI
What is the function of this protein?
May play a role in hematopoietic cell proliferation or differentiation.  Potential mediator of neuronal apoptosis.
What are the official names of this protein?
SNF-related serine/threonine-protein kinase, SNF1-related kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYP_BORAP
Sequence: MSDFIASKEDDYSKWYLDIVQKAKLADYSPVKGCMVIMPYGYSIWSKIQSILDKKFKETGHENAYFPMLIPYGFLEKEKDHIDGFSPEFAIIKDAGGESLVEPLVLRPTSETIIWNMYSKWIKSYRDLPLKINQWANVIRWEKRTRPFLRTTEFLWQEGHTAHATEEEALEETLLILDVYKRFMEDYLAIPVFCGKKSENEKFAGAVSTYSVEALMQDKKALQAATSHYLGLNFAKAFDVKFQDKDGKMKHVFASSWGVSTRLIGALIMVHSDEKGLILPPRIAPVEIIVIPIFKKEDEINKKILDYSDCVVHTLKKAEFRVEIDKDVRSSPGFRFSSAEFKGIPIRIEVGINDILLNSVTIIRRDKDRKFKYQISLDSLVSKVRVELDSMQKDLFKKALNFRTLNTKEIFRSGKDSYELFKAYVNDYSGFVLSCWCGGLNCENIIKNETKATIRCIPDDFKARDLTGMTCIYCSSKAKYYVLFAKSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_BACSU
Sequence: MKHLTTMSELSTEEIKDLLQTAQELKSGKTDNQLTGKFAANLFFEPSTRTRFSFEVAEKKLGMNVLNLDGTSTSVQKGETLYDTIRTLESIGVDVCVIRHSEDEYYEELVSQVNIPILNAGDGCGQHPTQSLLDLMTIYEEFNTFKGLTVSIHGDIKHSRVARSNAEVLTRLGARVLFSGPSEWQDEENTFGTYVSMDEAVESSDVVMLLRIQNERHQSAVSQEGYLNKYGLTVERAERMKRHAIIMHPAPVNRGVEIDDSLVESEKSRIFKQMKNGVFIRMAVIQRALQTNVKRGEAAYVISH
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MLTC_SHIB3
Sequence: MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLKNRLQSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GATA_METM6
Sequence: MITDRVSDYLEKIEKSDVNAFIDVNSEKVLKEAEELEKNDYLKNKPLYGKIVAVKSNINVKGYKISCASKTLEKYTGTYDATVVKKLRLQGALIVGMTNMDEFASGSSGETSYFGPTKNPAAMDRIPGGSSSGSAAAVAADLCDMAIGSDTGGSIRNPASHCGIVGFKPSYGVVSRQGLCDLAMSFDQIGPLTKNAEDALVLTNAIKGIDRSDSTSLETPKFEKKDISNYKVGVVKEFMDVTDEKIRNEIEKGIEVFKDMGCKIVDLSYKYIDLALPTYYLINYVEFFSATRKYDGRRYGEFIEEACGEEVLRRILIGKHISEQEFSGKYYKKALQARKAMKKEMLGLFNSADLIVGPTVPKLPHKLGEDLSPMEMYAYDVLTVPTNICGICSGVVRCGNIQGVPVGLQIQGAPLEDEKVLSAMIEFEKNY
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MIAB_CLAMS
Sequence: MSTVAEHVRAAPSSVDRPRTYEVRTYGCQMNVHDSERLTGSLEAAGYVSAEGAEADIVVINTCAVRENADNKLYGNLGHLAGVKRRHEGMQIAVGGCLAQKDRATVLEKAPWVDVVFGTHNMGALPTLLERARHNGEAQLEILESLETFPSTLPTKRDEIASGWVSISVGCNNTCTFCIVPALRGKEKDRRPGDILAEIQALVDDGAVEVTLLGQNVNSYGVEFGDRQAFGKLLRAAGAIEGLERIRFTSPHPAAFTDDVIDAMAETPAVMPQLHMPLQSGSDRILKAMRRSYRSERFLGILDRVRTRVPDAAITTDIIVGFPGETEEDFQETLRVVEAARFSSAFTFQYSIRPGTPAATMEEQVPADVVKERYGRLTALQERISHEENQRVVGRTVEVLVSAHEGRKDGDTRRVTGRAQDGRLVHLDVPEGSAEPRPGDAVDVEVTRAAPFHLIADSVDGAPLRIRRTRAGDAWERAQADSCGVPTPATGASAGAAPRVSLGLPTLRVPTTASTSAPVGDGSAHPRHRA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_ACIBS
Sequence: MPRSLKKGPFVDAHLFAKVEAAVASNSRKPIKTWSRRSMILPDFVGLTISVHNGRNHVPVIVTEHMVGHKLGEFAPTRTYRGHGVDKKSKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SARX_STAAB
Sequence: MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNDDDISKFNALFEDVEQFLNI
What is the function of this protein?
Involved in the regulation of virulence genes.  Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb.  Binds directly to the agr promoter region (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarX, Staphylococcal accessory regulator X.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT1_COREF
Sequence: MLNLPRLLYPLYERRLLKELNGARQPGHVAIMCDGNRRWAREAGFVDLSHGHRVGAKKIGELVRWCDDVDVDLVTVYLLSTENLGRDEAELQLLYDIIGDVVAELSLPETNCRVRLVGHLDLLPKEFAERLRGTVCETVDHTGVAVNIAVGYGGRQEIVDAVRDLLTSARDEGKTLDEVIESVDAQAISTHLYTSGQPDPDLVIRTSGEQRLSGFMLWQSAYSEIWFTDTYWPAFRRIDFLRALRDYSQRSRRFGK
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: OBG_STRGG
Sequence: MTTFVDRVELHAAAGNGGHGCASVHREKFKPLGGPDGGNGGRGGDVILVVEQSVTTLLDYHHSPHRKATNGQPGAGDNRSGKDGQDLVLPVPDGTVVLDKAGNVLADLVGQGTTFVAGQGGRGGLGNAALASARRKAPGFALLGEPGESRDIVLELKTVADVALVGYPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVTAGSTVYTIADVPGLIPGASQGKGLGLEFLRHVERCSVLVHVLDTATLESDRDPVSDLDMIEEELRLYGGLENRPRIVALNKVDIPDGQDLADMIRPDLEARGYRVFEVSAIAHKGLKELSFALAGIIAEARATKPKEEATRIVIRPRAVDDAGFTVTLEDDGIYRVRGEKPERWVRQTDFNNDEAVGYLADRLNRLGVEDSLMKAGARAGDGVAIGPEENAVVFDWEPTVTAGAEMLGRRGEDHRLEEPRPAAQRRRERDAERDDAEKEYDEFDPF
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC1_STAES
Sequence: MKKKALLPLFLGIMIFLAGCDYSTPEKQDGFFFNTFVQPMKHLLQWLGNDVFHNNFGLAIIVLVLFIRLILLPFMLSNYKNSHMMREKMKVAKPEVDGIQEKVKRARTQEEKMAANQELMEVYKKYDMNPMKSMLGCLPILIQMPIIMGLYFVLKDKLVNGLSEHPHFLWFNLTKPDIWITVIAGVLYFIQAVVSSKTMPQEQRQMGYMMMVISPIMIIWISLQASSALGLYWSVSALFLVIQTHFANIYYSKLAKKEVQPFIEKYEREHNPYSKKKGKNTQVVSKKNKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 1, Foldase YidC 1, Membrane integrase YidC 1, Membrane protein YidC 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VM11_BOTAT
Sequence: TPEQQRYVDLFIVVDHGMFMKYNGNSDKIRRRIHQMVNIMKEAYSTMYIDILLTGVEIWSNKDLINVQPAAPQTLDSFGEWRKTDLLNRKSHDNAQLLTSTDFNGPTIGLAYVGSMCDPKRSTGVIQDHSEQDLMVAITMAHELGHNLGISHDTGSCSCGGYSCIMSPVLSHEPSKYFSDCSYIQCWDFIMKENPQCILNKR
What is the function of this protein?
Snake venom zinc metalloproteinase that acts on fibrinogen, fibrin, fibronectin (FN1), type I collagen, type IV collagen, integrin alpha-7/beta-1 (ITGA7/ITGB1) and integrin alpha-1/beta-1 (ITGA1/ITGB1).  Binds to fibronectin (FN1), fibrinogen and, weakly, to type I collagen and laminin.  Cleaves Xaa-Leu bonds.  Inhibits ADP- and collagen-induced platelet aggregation both in the presence (IC(50)=1. 4 uM for collagen) and in the absence (IC(50)=2. 2 uM for collagen) of cofactors.  Has hemorrhagic activity.
What are the official names of this protein?
Snake venom metalloproteinase atroxlysin-1, SVMP, Atroxlysin-I.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RHBG_CANLF
Sequence: MARSPRRAGAPRLQLPLLCLLLQGATAILFAVFVRYNHETDAALWHWGNHSNLDNEFYFRYPSFQDVHVMVFVGFGFLMAFLQRYGFSSVGFTFLLAAFALQWSTLIQGFFHSLHGGYIHVSVNSMINADFCAGAVLISFGAILGKTGPAQLLLMTVLEVALFGINEFVLLNLLQVKDAGGSMTIHTFGAYFGLVLSRVLYRPQLEKSKHRQCSVYHSDLFAMIGTIFLWIFWPSFNSAPTTLGDGQHRTALNTYYSLSASTLGTFAMSALVGERGRLDMVHIQNAALAGGVVVGTAGEMMLTPFGALAAGFLAGTVSTLGYKFFTPILEAKFKVQDTCGVHNLHGIPGVLGALLGVLVVGLATHEAYGEGLGSVFPLIAKGQRTAMSQAMYQLFGLFVTLMFASVGGALGGLLLKLPCLGSPADCQCYEDQVYWEVPGEHEDAAQGPLKAEEPDTQA
What is the function of this protein?
Ammonium transporter involved in the maintenance of acid-base homeostasis.  Transports ammonium and its related derivative methylammonium across the basolateral plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism.  May transport either NH4(+) or NH3 ammonia species predominantly mediating an electrogenic NH4(+) transport (By similarity).  May act as a CO2 channel providing for renal acid secretion (By similarity).
What are the official names of this protein?
Ammonium transporter Rh type B, Rhesus blood group family type B glycoprotein, Rh family type B glycoprotein, Rh type B glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: PLD3_PONAB
Sequence: MKPKLMYQELKVPAEEPANELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRPAPCYDPCEAVLVESIPEGLDFPNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLRQLQTLAPKGVNVRIAVSKPNGPQPQADLQALLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYDTRYNQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNVVDNARSFIYVAVMNYLPTLEFSHPHRFWPAIDDGLRRAAYERGVKVRLLISCWGHSEPSMRAFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERATYIGTSNWSGNYFTETAGTSLLVTQNGRGGLRSQLEAIFLRDWDSPYSHDLDTSADSVGNACRLL
What is the function of this protein?
5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (By similarity).  Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity).  May be important in myotube formation.  Plays a role in lysosomal homeostasis.  Involved in the regulation of endosomal protein sorting (By similarity).
What are the official names of this protein?
5'-3' exonuclease PLD3, Choline phosphatase 3, Phosphatidylcholine-hydrolyzing phospholipase D3, Phospholipase D3, PLD 3.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Lysosome lumen. Early endosome membrane; Single-pass type II membrane protein. Late endosome membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Localizes to ER-associated vesicles in differentiating myotubes. The soluble form in lysosome arises by proteolytic processing of the membrane-bound form.
Protein: PSF2_DROME
Sequence: MDPSIIEFIGEKCMISIIPNFSNEPLHLIYGPVGPFRAGFPVFVPLWMATHLRKQQKCRIVPPEWMDMDILEEIKEEEKRSKFFTKMPCEHYMVVAQLVMSTAPDDVPRCEELRTVIKDIFDIRESKLRTSIDAFIKGEGTYAKLDNLTLLEIHSVRPILPYSLDHIARYQRTATASQRDTSMLSASMAGSSSGPNSNSLFSQ
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.
What are the official names of this protein?
Probable DNA replication complex GINS protein PSF2, GINS complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y4705_BACC3
Sequence: MISQSTLFLFILLIIGLIAKNQSLTVAIGVLFLLKFTFLGDKVFPYLQTKGINLGVTVITIAVLVPIATGEIGFKQLGEAAKSYYAWIALASGVAVALLAKGGVQLLTTDPHITTALVFGTIIAVALFNGVAVGPLIGAGIAYAVMSIIQMFK
What are the official names of this protein?
UPF0756 membrane protein BCA_4705.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCP_ALHV1
Sequence: MAHARPKLPRINLRLDAEYPNDPRVQQLHLQILNNPNYANNVRAPLSYLVFLTAQEMYEVFVRQARGVNKKRSGGPEKPILPANPGAGPQNAPGCGGGGSGSGGSGPPGGSAPQIQPPNNGVPSNQVSSNSGSAAGSGSGSGASSNSGAGSGAGAGSSACPSSGAGSGAGAGSSAGSNVQAPPAPPPLPQVPMVPGVVNGQEMYLPLGPVNGLPQQLGTAGSDNSGGQASSPGSQNPPTKPVAPRGKLGKGR
What is the function of this protein?
Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument.  Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly.
What are the official names of this protein?
Small capsomere-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae small capsomere-interacting protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: EX7L_LACPL
Sequence: MSESQQYLTVTALTQYLKRKFEVDPYLGKVYLTGEVSNYRPRPNTHQYFSLKDDHAKISAIMFKSAFAKVKFQPEEGMKVLVVGRIGLYEPSGSYQIYVERMEPDGVGALYQAYEQLKKKLAAEGLFSAPKKPLPRFPKRIAVVTSRSGAVIRDIITTTRRRFPIAQIVLFPSQVQGDAAAAEISRQIERANAQGDFDTLIIGRGGGSIEDLWPFNEEVVARAIAQSQLPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVYNDVLLQLKQDQTRVFNAFQNFVQRDRQRLNKLQTSYVFTQPNRLYEGYLQKLDFLNERLKQAGQNNFNLASQHYQRVFQQLRQQTPIHQVRQAQTQLLNLQQRLNRGTQLVVRQKRQQLTQTVQSLDLLSPLKIMTRGYAFVTADEQVVHGVKQLQPEQTVAIHMADGEAQAQITKIDGGK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_SHELP
Sequence: MAVIKCKPTSAGRRHVVKVVNSDLHKGKPFAGLLAKKAKSGGRNNTGRITVRHVGGGHKQHYRIVDFKRNKDGIPAKVERLEYDPNRTANIALVLYADGERRYILAAKGMQAGDQIQSGIDAEIKAGNALPLRNIPVGSVVHAVEMKPGKGAQIARSAGTYVQVVARDGAYATLRLRSGEMRKVPVDCRATLGEVGNAEHMLRQLGKAGAKRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGVPTKGYKTRSNKRTDKYIVRRRNKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NUOB_CUPTR
Sequence: MAIEGVLNEGFVTTTADKLINWTRTGSLWPMTFGLACCAVEMMHAGAARYDMDRFGVIFRPSPRQSDVMIVAGTLCNKMAPALRKVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALIYGVIQLQNKIKRTNTIARKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FABA_RHOPA
Sequence: MRDRRSSYEYEDLLACGRGELFGAGNAQLPLPPMLMFDRITTITEDGGEFGKGHVRAELDVNPDLWFFACHFKNDPVMPGCLGLDAMWQMVGFFLGWVGGEGPGRALGLGELKFTGQVLPNISKVVYNVDIKRVMRSKLWLGIADGWLSADDEIIYRAKDLKVGLFKQTAQPVAG
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_ECO81
Sequence: MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRREDAKYRNQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ZUPT_ECO55
Sequence: MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENLYS_BPP22
Sequence: MMQISSNGITRLKREEGERLKAYSDSRGIPTIGVGHTGKVDGNSVASGMTITAEKSSELLKEDLQWVEDAISSLVRVPLNQNQYDALCSLIFNIGKSAFAGSTVLRQLNLKNYQAAADAFLLWKKAGKDPDILLPRRRRERALFLS
What is the function of this protein?
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles.  Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.
What are the official names of this protein?
Endolysin, Lysis protein, Lysozyme, Muramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 24 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane.
Protein: Y1054_FRAAA
Sequence: MADPSFDIVSKVDEQEIDNAVNQTAKEIRTRFDFRDTGASATLSGESILLVANTDERVKAVLDVLQEKFVKRGISLKALSFDEPKPSGKEFRLSVTVQQGIADDKARAIAKKIRADGPKGVQAQIQGDQLRVTGKKRDDLQRVIQLLKAEDFEVPLQFVNYR
What are the official names of this protein?
UPF0234 protein FRAAL1054.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ETR1_BRAOL
Sequence: MEVCNCIEPQWPADELLMKYQYISDFFIAVAYFSIPLELIYFVKKSAVFPYRWVLVQFGAFIVLCGATHLINLWTFTTHSRTVALVMTTAKVLTAVVSCATALMLVHIIPDLLSVKTRELFLKNKAAELDREMGLIRTQEETGRHVRMLTHEIRSTLDRHTILKTTLVELGRTLALEECALWMPTRTGLELQLSYTLRQQHPVEYTVPIQLPVINQVFGTSRAVKISPNSPVARLRPVSGKYLLGEVVAVRVPLLHLSNFQINDWPELSTKRYALMVLMLPSDSARQWHVHELELVEVVADQVAVALSHAAILEESMRARDLLMEQNVALDIARREAETAIRARNDFLAVMNHEMRTPMHAIIALSSLLQETELTPEQRLMVETVLKSSSLLATLMNDVLDLSRLEDGSLQLELGTFNLHTLFREVLNLIKPIAVVKKLPITLNLAPDLPEFVVGDEKRLMQIILNIVGNAVKFSKQGSISVTALVTKSDNRAPPDFFVVPTGSHFYLRVKVKDLGAGINPQDIPKLFTKFAQTQSLATRSSGGSGLGLAISKRFVNLMEGNIWIESEGVGKGCTAIFDVKLAISNESKQSGIPKVPANPQHVNFAGLKVLVMDENGVSRMVTKGLLVHLGCEVTTVSSNEECLRVVSHEHRVVFMDVCTPGVENYQIALRIHEKFTKRHQRPLLVALTGNTDKSTKEKCMSFGLDGVLLKPVSLDNMRNVLSDRLEHRVLYEAM
What is the function of this protein?
May act early in the ethylene signal transduction pathway, possibly as an ethylene receptor, or as a regulator of the pathway.
What are the official names of this protein?
Ethylene receptor 1.
What is the protein family that this protein belongs to?
Belongs to the ethylene receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ISCR_ERWT9
Sequence: MRLTSKGRYAVTAMLDVALHSHEGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKAADAIAVGAVITAVDESVDATKCQGKEGCQGGERCLTHVLWRDLSERISDFLNNITLAELVNNQEILVVADRQNSNEIRRAPHGRMHETINVNLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.