PharMolix/UniProtQA huggingface dataset:
Protein: SOS1_HUMAN
Sequence: MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP (PubMed:8493579).  Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:17339331).  Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).
What are the official names of this protein?
Son of sevenless homolog 1, SOS-1.
Protein: H13J1_CYRHA
Sequence: MKTAIFTVVLALAVFAVLSFGWEANEKALSEEFTELIHEKEAASETEARECRYFWGECHDHMPCCDWLVCRYKWSITYNICVWNRTFPEK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U7-theraphotoxin-Hhn1h, U7-TRTX-Hhn1h, Hainantoxin-XIII-10, HNTX-XIII-10.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 13 (Hntx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXB_SHEWM
Sequence: MKIIADENMPYVQELFGDLGIIETVNGRSLTAEMVKDADVLLVRSVTQVDASLLSKNSQLTFVGSATIGTDHIDTEYLTQRQISFSNAPGCNATAVGEFAFIAMLELANRFGTSLKDKVVGIVGAGNTGSAVARCLQAYGVEVLLHDPLIEKSDPRNFVSLDELITRANVISLHVPITKSGEHKTWYLFDESRLNSLNADTWLLNCCRGEVVDNRALINVKQQRADIKVVLDVWEGEPNPMRELIPYVEFATPHIAGYSLEGKARGTYMLYQKLMQVLGKKEEKEMLALLPSFWTEQLTLTKEPSEKALLQLSRFVYDLRDDDALFRATLLEDPSKKAPVNSSNNNGFDLMRKNHKHRREFSALTLATTGQSEVDWLLNLGYSGVGR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI_STRGG
Sequence: MLLAELAQVSLEVAATSARSRKTALLAGLFRNAGPEDVPVVIPYLAGRLPQGRIGVGWRSLGEPVEPACDPTLTVTGVDAELTALAATSGPGSQARRRERLRTLFAAATADEQRFLRALLTGEVRQGALDAVAADALAHAAGAPPADVRRAVMLAGSLQDVATVLLADGPGALADFRLTVGRPVQPMLARSAASVGEALDKLGPCAVEEKLDGIRVQVHRDGERIRAYTRTLDDITDRLPELVSAVAALHARRFVLDGELIALGEDGRPRPFQETASRVGSRRDVAGAAAHVPVVPVFFDALRVDGEDLLDRPFADRHAALARLLPDDLRVRRTVVADPDAPEARAAADAFLAATLERGHEGVVVKDLAAAYSAGRRGASWLKVKPVHTLDLVVLAVERGSGRRTGKLSNLHLGARRPDGTFAMLGKTFKGLTDALLDWQTARLRELATDDDGHVVTVRPELVVEIAYDGLQRSTRYPAGVTLRFARVLRYREDKTAREADTVETVLSRQR
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
Probable DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: DGTL1_ACTSZ
Sequence: MILSVNSAWLERFQADRPREKDHRPPFRRDRARILHSAAFRCLQAKTQIHAVGENDFYRTRLTHSLEVAQIGSSLASQLRFTEAFTSLTEQLNCSSKELESVLKPLLPSNDLIETLCFAHDIGHPPFGHGGETALNAMMRHSGGFEGNAQTFRIVTKLEPYTEKAGMNLTRRTVLGLVKYPAILDEASPQYSLLDLPHPTDLGHLRQIDWRPSKGLYRDDLTMINWLLKPLSDTDRRLFTSFRKVRSNFQEFLKTVYKSLDCSIMELADDIAYGVHDLEDAVVVGLISQSQWQAAYDELKNCSSDWMRKNVDTLTQKLFSDYHYERKNAIGALVNYFITHVRWKMTADFTDPLLRYNAELPDDVICVLNIFKDFVFKYVIRDVETQRIEFRGQRILTDMFQIFESDPERLLPRNTVKRWQNAEAEGRKRIICDYIAGMSDAYALRVHRQLS
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: TAL_PARMW
Sequence: MATLLDQLSAMTVVVADTGDLEAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALRSSRKLIGDAAPVEDVVHEALDEISVIFGKEILKIVPRRVSTEVDARLSYDTDATIEKGRKLIRLYNDAGISNDRVLIKIASTWEGIKAAEVLEKEGIHCNLTLLFGFGQAVACAEAGVTLVSPFVGRILDWYKADTGRDSYPGPEDPGVISVTRIFNYYKTYGYKTEVMGASFRNLDEITELAGCDLLTISPKLLDQLRESDASLSQKLDATNPSGGEEQIHVDRERFDAMMAADRMATDKLGEGIKGFSKAIETLEHQLAHRLAELEGGEAFRHAVQEIFMLNDMNGDGCITRDEWLGSDAVFDALDLDHDGRLTPEEVRKGFGAALTLTTA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CKX2_ARATH
Sequence: MANLRLMITLITVLMITKSSNGIKIDLPKSLNLTLSTDPSIISAASHDFGNITTVTPGGVICPSSTADISRLLQYAANGKSTFQVAARGQGHSLNGQASVSGGVIVNMTCITDVVVSKDKKYADVAAGTLWVDVLKKTAEKGVSPVSWTDYLHITVGGTLSNGGIGGQVFRNGPLVSNVLELDVITGKGEMLTCSRQLNPELFYGVLGGLGQFGIITRARIVLDHAPKRAKWFRMLYSDFTTFTKDQERLISMANDIGVDYLEGQIFLSNGVVDTSFFPPSDQSKVADLVKQHGIIYVLEVAKYYDDPNLPIISKVIDTLTKTLSYLPGFISMHDVAYFDFLNRVHVEENKLRSLGLWELPHPWLNLYVPKSRILDFHNGVVKDILLKQKSASGLALLYPTNRNKWDNRMSAMIPEIDEDVIYIIGLLQSATPKDLPEVESVNEKIIRFCKDSGIKIKQYLMHYTSKEDWIEHFGSKWDDFSKRKDLFDPKKLLSPGQDIF
What is the function of this protein?
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group (PubMed:14555694).  Modulates asymmetric cytokinin signaling in emerged lateral roots (PubMed:31387989).  Its activity determines cell elongation and number in emerged lateral roots and defines angular growth of lateral roots (PubMed:31387989).
What are the official names of this protein?
Cytokinin dehydrogenase 2, Cytokinin oxidase 2, AtCKX2, CKO 2.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Secreted, extracellular space.
Protein: DEOB_METEP
Sequence: MARALLIVLDSVGIGGAPDADRYGDAGSDTVGHIAEACAAGRGDRPGLRAGPLHLPNLAALGLGLACEGATGRVPPGLAPEGPVRALWGHAVETAAGKDTPSGHWEIAGVPVREAWGHFPDTQPAFPAELTAALVARAGLPGILGDCHASGTAIIEALGAEHVRTGKPICYTSADSVFQIAAHEEAFGLERLYETCRIAREVCDPYRVGRVIARPFLGSAAEGFRRTSHRKDFSVAPPAGTLLDGLETAGRAVVSVGKIGDIFAHRATGREIKPAGNAACLDAALDAFAGLPEGGFVFLNLVDFDTEHGHRRDVPGYAAELEAFDRRLPEIQAVLKPGDLCVITADHGNDPTWTGTEHTREQVPVLAFGPGLAPRALGRRESFADMGASVAAHLGLPPLGAGQAWW
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_SACD2
Sequence: MDASKSKALEAALSQIDRQFGKGTVMRLGDKGREKMPAISTGSLGLDVALGIGGLPKGRIVEIYGPESSGKTTLTLQVIAEAQRQGGTCAFVDAEHALDPVYAEKLGVNVDDLIISQPDNGEQALEVADMLVRSGAVDVLVVDSVAALTPKAEIEGDMGDHHVGLQARLMSQALRKITGNIKNANCLAIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGSVKEGDEVVGSDTRVKVVKNKVAPPFKQAEFQILYGQGINRLGEIVDFGVKLGLIDKAGAWYSYNGDKIGQGKANAMQYLRDNKEVAEFLEQKIKAELLGDIKPVAKEGAEVEEESAEQE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_XANOM
Sequence: MARIAGVNLPAQKHVWVGLQSIYGIGRTRSKKLCESAGVTSTTKIRDLSEPEIERLRAEVGKYVVEGDLRREIGIAIKRLMDLGCYRGLRHRRGLPLRGQRTRTNARTRKGPRKAIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: Y3020_STAA8
Sequence: MKKQDISVKTVVAIGIGAAVFVILGRFVVIPTGFPNTNIETSYAFLALISAIFGPFAGLMTGLVGHAIKDFTTYGSAWWSWVICSGIIGCLYGWIGLKLNLSSGRFSRKSMVYFNIGQIIANIICWALIAPTLDILIYNEPANKVYTQGVISAVLNIISVGIIGTILLKAYASSQIKKGSLRKE
What are the official names of this protein?
UPF0397 protein SAOUHSC_03020.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIP_ECHMU
Sequence: MGLSTYVGTFLLCILTLSHCKSGKEEYGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDGERLIGDAAKNQLTSNPKNTLFDAKRLIGRDYDDKDVQGDIKRYPFKVINKNNKPYMKVQVGSEEKGFAPEEVSAMVLSKMKEIAEAYLGTEVTHAVVTVPAYFNDAQRQATKDAGAIAGLTVLRIINEPTAAAIAYGLDKKDTEKNILVFDLGGGTFDVSLLTIDNGVFEVVATSGDTHLGGEDFDQRLIDYFVKLYKKKEGKDITKDDRAVQKLRREVEKAKRTLSTEHSTMIEIDNLFEGKDFSEPLTRARFEELNNDLFRSTLKPVMKVMEDSGLKKEDIDDIVLVGGSTRIPKIQQLVKEFFNVKEPSRGINPDEAVAYGAAVQAGVISGVEDTGDIVLLDVCPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVFEGERPMTKDNHFLGKFDLTGIPPAPRGLPQIEVTFEIDVNGILRVSAEDKGTGKKSNIVINKETNRLTPEEIERMIQDAEKFSDQDKQVKERVEVRNDLESLAYSIKNQVKDKEKMGGKLSDDEIKTIEDAADEAIKWMENNPQAETSDYKKQKANLESVVQPIVSKLYEGAAPPTESTPKEEL
What is the function of this protein?
Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen.  Involved in the correct folding of proteins and degradation of misfolded proteins (By similarity).  Acts as a key repressor of the unfolded protein response (UPR) (By similarity).
What are the official names of this protein?
Endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein homolog, GRP-78 homolog, Binding-immunoglobulin protein homolog, BiP.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: MABP1_HUMAN
Sequence: MAVEGSTITSRIKNLLRSPSIKLRRSKAGNRREDLSSKVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSGLLCEFSDRRLLDKWVELRNIDSFTTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASVTEASRLFSGVANARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEELPALPVLAKSTKKALASVPSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNPDSSWAPKRVATASPFSGLQKAQSVHSLVPQERHEASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSYQNPTTSSMAKISRSISVGENLGLVAEPQAHAPIRVSPLSKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAEKPGFPVGLGKAHSTTERWACLGEGTTPKPRTECQAHPGPSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQSRIAQLLRDTFSSVRQELEAVAGAVLSSPGSSPGAVGAEQTQALLEQYSELLLRAVERRMERKL
What is the function of this protein?
Negative regulator of NOD2 function.  It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response (PubMed:22700971).  Involved in JNK signaling pathway (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase-binding protein 1, JNK-binding protein 1, JNKBP-1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Not detected in the cilium. Localized around the poles of the mitotic spindle from prophase to anaphase in mitotic cells.
Protein: YPEL3_DANRE
Sequence: MVKQTKAKTFQAYLDSCHRRYSCVHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERLLLTGLHAVADIYCENCHTTLGWKYEQAFELSQKYKEGKFIIELSHMIKDNGWD
What is the function of this protein?
May be involved in proliferation and apoptosis in myeloid precursor cells.
What are the official names of this protein?
Protein yippee-like 3.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PHEA_MYCUA
Sequence: MARIAYLGPEGTFTQAALLEIAAAGLVPGHDDGGAQPLPVDSTPAALDAVRTGAAEFACVPIENSIDGSLAPTLDSLAIGSPLQVFAETTLDVAFSIVVKPGVGAADVRTLAAFPVAAAQVRQWLTAHLPNVELHPAYSNADGARQVAEGQVDAAVTSPLAAAHWALQSLADGVVDESNARTRFLLIGVPGPPPPRTGTDRTSAVLRIANVPGALLDALTEFGMRGIDLTRIESRPTRTGLGTYMFFIDCVGHIADDAVAEALKALHRRCADVRYLGSWPTGQTYAAQPPPADEAAIWLQQLREGKPEASPEPPL
What are the official names of this protein?
Prephenate dehydratase, PDT.
Protein: RS9_UREPA
Sequence: MQKSNIVEYKGLGRRKSSIARVKLVPGSGKVLVNDRQPENYFPNKLVIQDMMQPLVLTKTAETYDVYVKVIGGGFNGQAGAIRLGITRALIQTREDLKTDLRKAGLVTRDSRVKERKKFGLYGARRAPQFTKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MURG_AGRFC
Sequence: MNKGIVLLAAGGTGGHVFPAEALAHTLKARGYQVHLVTDSRAERYAGKFPADEIHVVPSATIGSKNPISVVRSLWKLWVGLRTARRLVTKLKPVAVVGFGGYPTVPPLLASTGLGVPSIIHEQNAVMGRANKALAARVKAIAGGFLPPANGQYSEKTVATGNPVRPAVLAASEIPYTPSQTGETFQLVVFGGSQGAQFFSSAVPAAICLMKDEQRKRIVVTQQARPEDKDSVIASYQKLGVKADVSPFFGDMASRIGEADLVISRSGASTVSELSVIGRPSILVPYPHALDHDQAANAAALSAAGGASVIKQAELSPQKLSSLLSSALAEPDRLSATAAAAKATGKPHAADVLADLVEAIAEGRSVQEFKKKNEGVGA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CARA_CHLTE
Sequence: MQEIPAILVLENGSVYRGTAFGHAGEATGEVVFNTSLTGYQEILTDPSYTGQMVVMTYPLIGNYGITPNDNESKKIWASALIVREASNVYSNYESTRSLDATLKEAGVMGLAGIDTRKLVREIRQKGAMRAVISTLCDDVAALKAQAAAIPEMTGLDLVQRVTTGERYTVDNPDAKYHVVAFDYGIKTNIIRQLNAEGCKVTVVNAKTTADEVLAMNPDGIFLSNGPGDPFAVTYAIDTIRELAARNSTLPIFGICLGHQLLSLAFGAKTYKLKFGHHGANHPVKNLLSNTIEITSQNHGFAVEMESLPGELELTHKNLYDMTVEGIRHRELPCFSVQYHPEAAPGPHDSHYLFKEFTELMERLKN
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: FUBP3_HUMAN
Sequence: MAELVQGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPPAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSSQPNYSKAWEDYYKKQSHAASAAPQASSPPDYTMAWAEYYRQQVAFYGQTLGQAQAHSQEQ
What is the function of this protein?
May interact with single-stranded DNA from the far-upstream element (FUSE).  May activate gene expression.
What are the official names of this protein?
Far upstream element-binding protein 3, FUSE-binding protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: DDC1_YEAST
Sequence: MSFKATITESGKQNIWFRAIYVLSTIQDDIKITVTTNELIAWSMNETDTTLCQVRFQKSFFEEYEFKPHEIVFGENGVQVIEDTYGNSHKLYSFRVNGRHLTTISRKPDGDGIKSFTIAVNNTSTCPESLANRLIVVIEMDSLIVKEYCPQFQPIKYDPIIINLKYKRRFLDVFGTAASDRNPQEPLDPKLLDVFTNTERELTSALFNEEVESDIRKRNQLTAADEINYICCNSTLLKNFLDNCNVNVTDEVKLEINVHRLSITAFTKAVYGKNNDLLRNALSMSNTISTLDLEHYCLFTTIEDEKQDKRSHSKRREHMKSIIFKLKDFKNFITIGPSWKTTQDGNDNISLWFCHPGDPILMQMQKPGVKLELVEVTDSNINDDILEGKFIKTAISGSKEEAGLKDNKESCESPLKSKTALKRENLPHSVAGTRNSPLKVSYLTPDNGSTVAKTYRNNTARKLFVEEQSQSTNYEQDKRFRQASSVHMNMNREQSFDIGTTHEVACPRNESNSLKRSIADICNETEDPTQQSTFAKRADTTVTWGKALPAADDEVSCSNIDRKGMLKKEKLKHMQGLLNSQNDTSNHKKQDNKEMEDGLGLTQVEKPRGIFD
What is the function of this protein?
Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.  Associates with sites of DNA damage and modulates the MEC1 signaling pathway and the activation of RAD53 in response to DNA damage at phase G1.  The complex also physically regulates DNA polymerase zeta-dependent mutagenesis by controlling the access of polymerase zeta to damaged DNA.
What are the official names of this protein?
DNA damage checkpoint protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EAF3_ASHGO
Sequence: MAFEIDGKCLCYHGPLLYEARVLRVYDPASQTYRDRTRTGVPLEEEDGLPAESRGREHWFVHYQGWKSTWDEWVGQERIRPYNDENLALKRQLVQDAKAAAAAAKRAKARPGKRERSPAPAAPAAPAQGPRLAVRMPVELKALLVDDWERITKERKLVALPCAPTVGDILDAYYRERTAQLASPVAQTLLHEFVEGVHLYFDQCLSHLLLYRLERLQFDEACGGAAPAASGLPAPPEPRPSAVYGGVHLLRLLSMMPELICGTTMDEKSCHTVVAQCESLLAWMATHADDLVSGDYINTSAQYEGVALGM
What is the function of this protein?
Involved in deacetylation of histones, chromatin assembly and chromosome segregation.  May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF3.
What is the protein family that this protein belongs to?
Belongs to the MRG family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS1_STAAB
Sequence: MLRIAIAKGRLMDSLINYLDAIEFTTLSETLKNRERQLLLSVDNIECILVKGSDVPIYVEQGIADIGIVGSDILDERHYNVNNLLDMPFGACHFAVAAKPETTNYRKIATSYVHTAEAYFKSKGIDVELIKLNGSVELACVVDMVDGIVDIVQTGTTLEANGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_PECAS
Sequence: MFYPDPFDVIVIGGGHAGTEAAMASARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEIDAMGGLMARAVDQAGIQFRILNSSKGPAVRATRAQADRVLYRQAIRTALENQPNLTIFQQAVDDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLARRLRELPLRVNRLKTGTPPRIDARTIDFSVLPQQHGDNPMPVFSFLGNAGQHPAQMPCYITHTNEKTHEVIRNNLDRSPMYAGIIEGIGPRYCPSIEDKVMRFADRNTHQIFLEPEGLTSNEIYPNGISTSLPFDVQWQIVRSMAGMENARIVRPGYAIEYDFFDPRDLKPTLENKFVHGLFFAGQINGTTGYEEAAAQGMLAGLNAARLSADKEGWSPRRDQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEMGRELGMVDDHRWARFNEKLENIEKERQRLRDIHVHPQSELLDQVNSLLKTPLSREANGEELLRRPEVDYAQLTALPLFAPGLTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENALLPADLDYKQVNGLSNEVIAKLNDHKPSSIGQASRISGITPAAISILLIWLKKQGLLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_ATRBE
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PURL_LACLA
Sequence: MTLEMSPEQIQESKIYREWGLTDEEYLKIKDEILDGRLPNFTETGMYAVMWSEHCCYKNSKPVLKKFPTTGPQVLMGPGEGAGVVDIGDDLAVVFKAESHNHPSYVEPYEGAATGSGGIIRDIFSMGARPIAILDSLRFGPIDNGKTRHIVDQVTAGIAGYGNCIGIPTVGGEVAFDESYAGNPLVNVMCVGLIEHKHIQKGQAKGVGNSIFYVGAKTGRDGIHGASFASKEFGSGSETQRSAVQVGDPFMEKLLLEACIEVIQNHGDILVGIQDMGAAGLVSSTSEMASKAGSGLRLNLDNVPQRETEMIPYEMMLSESQERMVLCVKKGHEQEIIDLFKKYDLDAVNIGQVTDDGFYTLYHKGEMVAHVPVDSLAEDAPTYYREAKVPERIQKFTDSEKYLPEITDSAVSEIFKKLLAQPTIASKKSIYETYDSRVMTNTVVAPGSDSAVLRVRGTNKALAMTTDCNARYLYLDPEKGGAIAVAEAARNIVASGGKPLAITDCLNFGNPEKPEQFWELTTAADGISRSCLALDTPVISGNVSLYNETNGSAILPTPMIGMVGLIENVKNITTQEFKKAGDLIVLVGQTFDDFSGSELQKMLIGEISGRIDFDLETEKINQDFVLKAITDGLVSSAHDLAEGGLAIALAESAFANGLGVDVKVDITNAQLFSETQGRFILSISPENQATFEKLLTESSVSGEVIGKVTDSGILEMNELSISTDEAVSIYEGALPALMK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.