PharMolix/UniProtQA huggingface dataset:
Protein: EX7S_RHIEC
Sequence: MTDSAKPEVSGLSFEKAVAELESIVARLERGDVALDESIEIYERGEALKKHCETLLSAAENRIEKIRLDRAGKPRGVEPLDGA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_PECCP
Sequence: MTLLALGINHKTAPVSLRERVVFSPDKLGVALDSLLQQPLVQGGVVLSTCNRTELYLSVDEQENQREQLIRWLCEYHQLRPEDVNGSLYWHQDNAAVSHLMRVASGLDSLVLGEPQILGQVKKAFAESQRGHSLSSELERLFQKSFTVAKRVRTETDIGASAVSVAFAACTLARQIFESLADVTVLLVGAGETIELVARYLREHNVQKMVIANRTRERAQALATEVGAEVITLAELDEQLVQADIVISSTASTLPIIGKGMMERTLKARRNQPMLMVDIAVPRDIEPEVGKLPNVYLYSVDDLHAIIQHNLAQRKAAAVQAESIVQQESSDFMAWLRAQSAVETIRDYRAQADELRAEMTAKALAAIQQGNDVEAVIQELTHRLTNRLIHAPTKSLQQAARDGDQNRLQILRDSLGLD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: Y608_ENCCU
Sequence: MRWKHGGPWVLIIIYNMIHHCSSGLERIVSFKLEPGSQVIVFPFIFEGYNIIALPTTKYSDLKKNPKDMKSLTPFFFNASHIIWDFAIGSVIRTPDNRFERLFNERMEGYLKDISVNVLKMYVKGNKTISELLEAVYERIFRCDEKGGGHMMKYIEDVIKGFDDMIENVPTEMDSERKEIYHRFWSGSRKYVESFYSIERLKHLVELEKMVCSACREICLGLKEEKLMGLFAEGSMRKALKAKLGEEEASRRGYLEYAIINDEILLDAHREHTGEVTKELVMQMLLGKNGEEIDRRYIGKVANVVKERQKRREREMEKSMKELLRDEEKAKSKKGRKKKSVGVSETKKEESETEEVEASEEMEISSVEVGGARRKTGKKSKGGRKCFKIHRRVLRWRKSPEKIKEELDRGREERWRGKSLEYIKEQKVLHDIAGVLELLRSEDADKFFMDTGEHSKGGSSRRRLMAIGVLEVGRRRMTGVVEAGTFKDSSGCTVLYHLMFRVTGIEEIGSVMSPEFAEANDIEKIDEDEECQDAGKFVYPKGVRFETVKDDDAFQIVWRNPSDTSEVLQGLTIQRRPYVI
What are the official names of this protein?
UPF0329 protein ECU06_0080.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: TBPL1_MOUSE
Sequence: MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSGKIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL
What is the function of this protein?
Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes (By similarity).  Seems to also mediate the transcription of NF1.  Does not bind the TATA box.
What are the official names of this protein?
TATA box-binding protein-like 1, TBP-like 1, 21 kDa TBP-like protein, TATA box-binding protein-related factor 2, TBP-related factor 2, TBP-like factor, TBP-related protein.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YIDC2_STAEQ
Sequence: MKKKALLPLFLGIMIFLAGCDYSTPEKQDGFFFNTFVQPMKHLLQWLGNDVFHNNFGLAIIVLVLFIRLILLPFMLSNYKNSHMMREKMKVAKPEVDGIQEKVKRARTQEEKMAANQELMEVYKKYDMNPMKSMLGCLPILIQMPIIMGLYFVLKDKLVNGLSEHPHFLWFNLTKPDIWITVIAGVLYFIQAVVSSKTMPQEQRQMGYMMMVISPIMIIWISLQASSALGLYWSVSALFLVIQTHFANIYYSKLAKKEVQPFIEKYEREHNPSSKKKGKNTQVVSKKNKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 2, Foldase YidC 2, Membrane integrase YidC 2, Membrane protein YidC 2.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZHD5_ARATH
Sequence: MDMRSHEMIERRREDNGNNNGGVVISNIISTNIDDNCNGNNNNTRVSCNSQTLDHHQSKSPSSFSISAAAKPTVRYRECLKNHAASVGGSVHDGCGEFMPSGEEGTIEALRCAACDCHRNFHRKEMDGVGSSDLISHHRHHHYHHNQYGGGGGRRPPPPNMMLNPLMLPPPPNYQPIHHHKYGMSPPGGGGMVTPMSVAYGGGGGGAESSSEDLNLYGQSSGEGAGAAAGQMAFSMSSSKKRFRTKFTTDQKERMMDFAEKLGWRMNKQDEEELKRFCGEIGVKRQVFKVWMHNNKNNAKKPPTPTTTL
What is the function of this protein?
Putative transcription factor.  Binds DNA at 5'-ATTA-3' consensus promoter regions.  Regulates floral architecture and leaf development.  Regulators in the abscisic acid (ABA) signal pathway that confers sensitivity to ABA in an ARF2-dependent manner.
What are the official names of this protein?
Zinc-finger homeodomain protein 5, AtZHD5, Homeobox protein 33, AtHB-33.
What are the subcellular locations of this protein?
Nucleus. Note=Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm.
Protein: NAC48_ORYSJ
Sequence: MSGGQDLQLPPGFRFHPTDEELVMHYLCRRCAGLPIAVPIIAEIDLYKFDPWQLPRMALYGEKEWYFFSPRDRKYPNGSRPNRAAGSGYWKATGADKPVGSPKPVAIKKALVFYAGKAPKGEKTNWIMHEYRLADVDRSARKKNSLRLDDWVLCRIYNKKGGLEKPPAAAVAAAGMVSSGGGVQRKPMVGVNAAVSSPPEQKPVVAGPAFPDLAAYYDRPSDSMPRLHADSSCSEQVLSPEFACEVQSQPKISEWERTFATVGPINPAASILDPAGSGGLGGLGGGGSDPLLQDILMYWGKPF
What is the function of this protein?
Transcription activator that binds to the promoter of the stress response gene LEA19.  Involved in tolerance to abiotic stresses (PubMed:20632034).  Transcription activator involved in response to abiotic and biotic stresses.  Involved in drought and salt stress responses, and defense response to the rice blast fungus (PubMed:17587305).  Transcription activator involved tolerance to cold and salt stresses (PubMed:18273684).  Transcription activator involved in tolerance to drought stress.  Targets directly and activates genes involved in membrane modification, nicotianamine (NA) biosynthesis, glutathione relocation, accumulation of phosphoadenosine phosphosulfate and glycosylation in roots (PubMed:27892643).  Controls root growth at early vegetative stage through chromatin modification and histone lysine deacytaltion by HDAC1 (PubMed:19453457).
What are the official names of this protein?
NAC domain-containing protein 48, ONAC048, OsNAC6, Protein STRESS-RESPONSIVE NAC 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: YC49L_SYNY3
Sequence: MNALSIPTWMVHVSSVIEWIVAIALVSRYATKAGYGHWRALAWGMVPALVSATCACTWHFFDNASQLDWLVTLQALTTVIGNITLCLAAWWIYRQSAQPSAPKP
What are the official names of this protein?
Ycf49-like protein.
What is the protein family that this protein belongs to?
Belongs to the ycf49 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATB_YEAS1
Sequence: MLQLARFYSLARTKAIHSHGAPFRPEYALKCGLEIHTQLNTKNKLFSQSTNSATSLVDAPNHHTSYYDIALPGTQPVLNLEAILFAMKLSLALGSQVNSISQFDRKHYFYGDQPQGYQLTQHYRPFARGGKINLSKELDDIDESAKEIGILQLQIEQDTGKSHYTETDKDVITLVDLNRSNVPLIELVTKPDFSDIKQVRAFIKKYQNLVRHLHISSGDLETGAMRVDVNLSINEYARVELKNLPNTSSIINAIKYEYQRQVELISVGDTSSLMEPETRGWTGSSTVKLRSKETTIDYRYMPDPELPYINLAQDVISGVRGLMPQLPDDIMRMLMKKPYQLSLKDAKILTYNSNQNDMYNHEALRSYYLDTFREFSKLAGERSNAKLPTNWIIHEFLGDLNKLQIPLARAKEILPPPVFAQFLKLLHEEVISATSGKMLLFHILENFKQSNCQDLSIPDFSKLIEKFELHAINQVDPQELMDLCNDVIAQHTDDTFIRNLVTGKKKSSLKFLIGQGMRRSQGRIKANEFEKKFKEILNIQW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SPAN1_LAMBD
Sequence: MSRVTAIISALVICIIVCLSWAVNHYRDNAITYKAQRDKNARELKLANAAITDMQMRQRDVAALDAKYTKELADAKAENDALRDDVAAGRRRLHIKAVCQSVREATTASGVDNAASPRLADTAERDYFTLRERLITMQKQLEGTQKYINEQCR
What is the function of this protein?
Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit (PubMed:22904283, PubMed:23387988, PubMed:25870259).  The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin have permeabilized the inner membrane and degraded the host peptidoglycans (PubMed:25870259).  Host outer membrane disruption is due to local fusion between the inner and outer membrane performed by the spanin complex (PubMed:25870259).
What are the official names of this protein?
Spanin, inner membrane subunit, i-spanin, Lysis protein Rz.
What is the protein family that this protein belongs to?
Belongs to the Lambdavirus i-spanin family.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: GRIN3_HUMAN
Sequence: MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTPGDKKKQLGADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAPSSVLD
What is the function of this protein?
May be involved in neurite outgrowth.
What are the official names of this protein?
G protein-regulated inducer of neurite outgrowth 3, GRIN3.
Protein: PYRF_XYLFM
Sequence: MMNHTPLLLGIRERLIFALDVPSRTQALEWIDQLGDAISFYKIGMELLASGEYFQVLDDLASRGKRVFVDLKFFDIPATVAGVIRRLSQWPISYCTIHGWHAPMMQAATEANTSNMHLLAVTVLTSMTREDLAKMGINREPVDVVVERALAAHMAGMSGVIASGQEAAAIRRAVGSGFSIVCPGIRTNHVPHNDQQRTIGIKAAFANGADAIVVGRPIRMAQDPQAAAEAMQTEIMTALTEPST
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: HISX_BACFR
Sequence: MKLIKYPDRSQWNEILKRPVLETENLFDTVRNIINRVRAGGDRVVMECEAVFDKAELTSLAVTSAEIEEAEKEVPIELKAAIYLAKRNIETFHSAQRFEGKKVDTMEGVTCWQKAVAIEKVGLYIPGGTAPLFSTVLMLAIPAKIAGCKEIVLCTPPDKNGKVHPAILFAARLAGVSKIFKVGGVQAIAAMAYGTESIPKVYKIFGPGNQYVTAAKQLVSLRDVAIDMPAGPSEVEVLADESANPVFVAADLLSQAEHGVDSQAMLVTTSEKLQTEVVYEVERQLGYLTRRDIAEKSLANSKLILVKDMEEALELTNAYAPEHLIIETKDYMEVAGQIVNAGSVFLGAFSPESAGDYASGTNHTLPTNGYAKAYSGVSLDSFIRKITFQEILPSGMSAIGPAIEVMAANEHLDAHKNAVTVRLEEIRK
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: ARGR_PSEAE
Sequence: MTAQPQRIGFLLWPATRALTLSLAEEALRAARRLHPEALYEPLFLLAEAPAEEEGWRLPGTAWNGRLEQCSRLFLVADEAPAAVSPALGLALKQLARSGAAIGALSAGIYPLAQLGLLDGYRAAVHWRWHDDFTERFPKVIATNHLFEWDRDRMTACGGMAVLDLLLALLSRDHGAELAGAVSEELVVERIREGNERQRIPLKNRLGSSHPKLTQAVLLMEANIEEPLTTDEIAQHVCVSRRQLERIFKQYLNRVPSQYYLELRLNRARQMLMQTSKSIIQIGLSCGFSSGPHFSSAYRNFFGVTPREDRNQRRGGSAFETTFTPVERG
What is the function of this protein?
ArgR could be a transcriptional activator of the dauBAR operon in response to the presence of L-Arg.
What are the official names of this protein?
HTH-type transcriptional regulator ArgR.
Protein: CISY_HELPJ
Sequence: MSVTLINNENNARYEFETIECTRGPKAVDFSKLFETTGFFSYDPGYSSTAGCQSKISYINGKKGELYYRGHRIEDLVAKYKYVDVCRLLLTGELPKNQDESLEFELELRHRSFVHESLLNMFSAFPSNAHPMAKLSSGVSILSTLYSTHQNMHTEEDYQTMARRIVAKIPTLAAICYRNEVGAPIIYPDIARSYVENILFMLRGYPYSRLKHTTQGEVGITPLEVEAFDKILTLHADHGQNASSTTVRNVASTGVHPYAAISAGISALWGHLHGGANEKVLLQLEEIGDVKNVDKYIARVKDKNDNFKLMGFGHRVYKSYDPRAKILKGLKDELHQKGVKMDERLSEIAAKVEEIALKDEYFIERNLYPNVDFYSGTILRALKIPVRFFTPVFVIGRTVGWCAQLLEHVKSPQARITRPRQVYVGD
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: Y239_METJA
Sequence: MKNMDVYEILYQFCLEYEVLLDDEKIPLWKLKKEDLDKVDLDLPWTSIRDLAIYLYELKKKQQNSKELIKCDIVEILVGIALLKPEEGSNYMGLVTEDMCLTYLSELITARINCIARYYYMMKKPQNTNIFDEIILKFPQKKDIRASNINDLRELVGKIRNYFK
What are the official names of this protein?
Uncharacterized protein MJ0239.
Protein: PFDB_HALS3
Sequence: MQGNLPPEAQEKLEQLQDLQEKAQNVATQKQQAEQQLSEAETALDALGDIEESTTMYREVGELLVETEYDNAHDDLDEKVSDLEVRVETLQKQEDRVQEQFESLQEELQDMLGGAGGAMGGGPGA
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMS_PIG
Sequence: MLSCRLQCALAALSIVLALGGVTGAPSDPRLRQFLQKSLAAAAGKQELAKYFLAELLSEPNQTENDALEPEDLSQAAEQDEMRLELQRSANSNPAMAPRERKAGCKNFFWKTFTSC
What is the function of this protein?
May enhance low-glucose-induced glucagon release by pancreatic alpha cells.  This effect may be mediated by binding to GPR107 and PKA activation (By similarity).  May regulate cardiac contractile function (By similarity).  May compromise cardiomyocyte viability.  In the central nervous system, may impair memory retention and may affect hippocampal excitability.  May also have anxiolytic and anorexigenic effects.  May play a role in arterial pressure regulation (By similarity).  May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH.  Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH (By similarity).
What are the official names of this protein?
Somatostatin.
What is the protein family that this protein belongs to?
Belongs to the somatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TTL13_MOUSE
Sequence: MEPNNCKTSESEEDDIEEEESEEECVREESTTPNSTQQALRKADYKEFENGVALSVVAKKIPKKILSATDTDDLEVGRRRRKRKRRPLAINLTNCKYESVRRAAQMCGLKEVGEDEEWTVYWTDCSVSLERVMDMKRFQKINHFPGMTEICRKDLLARNLNRMQKLYPTEYNIFPRTWCLPADYGDFQAYGRQRKTRTYICKPDSGCQGRGIFITRTPKEIKPGEHMICQQYITKPFLIDGFKFDMRIYVLITSCDPLRIFMYEEGLARFATMPYVEPSHNNLEEVCMHLTNYAINKHNENFVRDDAVGSKRKLSTLNAWLREHSHDPQELWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLCGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTTDSRLDREVKDALLCDAMNLVNLRGCDKKKVIEEDKRRVKERLFPCHQQPRETRREQFELSQAAMHDQERYEDSHLGGYRRIYPGPDSEKYAPFFKHNGSLFQETAASKAREECARQQLEEIRLKQEQQENPGTKKRKENKEQNQGESAGEKSRSRTATRVLATSLAYRNRNREKELLPVQLDTTQPQDIVEEEELERMKLLLQRENLIRSLGIVEQLTRMLYPSHRSHRKLHEYRPRFHQDGLSSQELQPVNLVPLVLLRGAASEQIPPHFLQPLRPHELIPRILGPLSSINPAIAQHSRYHLQPKNFNWIGDSAATGPCSLSMKKSGRHYISSSRVRLTSRKRRKAQHSTKTANGLQSLLIERLPTSSRLKSSGQDLCLQKAKNTETPRVLQHSKILWGSVKTKR
What is the function of this protein?
Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin (PubMed:17499049).  Mediates ATP-dependent polyglutamate side-chain elongation of the polyglutamylation reaction but not the initiation step (PubMed:17499049).  Preferentially modifies the alpha-tubulin tail over a beta-tail (PubMed:17499049).
What are the official names of this protein?
Tubulin polyglutamylase TTLL13, Tubulin--tyrosine ligase-like protein 13.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
Protein: AMPA_STRM5
Sequence: MALEFTLNHLAAASAAVDCLVVGAYADHTLTAAAQALDAASGGRLAALAQRGDLSGKTGATTLLHDLPGVTAPRVLVVGLGEAARFGVPQYLKAVGDAVRALKAGAVRSALFTLSEVAVKDRDAAWAIRQAVIAADHAAYRYTATLGKKKADDAGLAQLAIAGDDAQALAQGQAIAAGVEFARELGNLPPNYCTPAYLAEVGVKFAGEHDGAEAEILDEHQMEALGMGSLLAVARGSANRPRLVVLKWNNGGDAKPYVLVGKGITFDTGGVNLKTQGGIEEMKYDMCGGANVIGTFVAAVKAKLPLNLVVVVPAVENAIDGNAYRPSDVITSMSGKTIEVGNTDAEGRLILCDALTYAQRFEPAALVDVATLTGACMVALGHQTAGLMSKHDDLANELLAAGEQVFDRAWRLPLWDEYQPMLDSTFADVYNIGGRWAGAITAGCFLSRFAEGQRWAHLDIAGVASDEGKRGMATGRPVGLLSQWLLDQAARA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_MYCPN
Sequence: MNQFEPKFTLIDTVSNQSVVLEQKQINIYLCGPTVYNDLHLGNTRPLIVFDVLQRVLQAAQYKVQFVQNITDIDDKIIKIAQQQEISEAQLCKQQITAYKSLLKKLNILPIKHLQVTDKIDKMPGYIARLVKKGFAYVSPLGNTYFSVSQLPQYGILANRVVETIEDEATDKRNKLDFVLWKQTTAGVKWNSPWGWGRPGWHVECAFLIDYSFKDQLTIHGGGVDLKFPHHENENAMHMALYDKPLTQHWMHIGHLMFENQKMSKSLQNFLLAVDFLTIHDFRILRWLFYQKHYYHPLDLSQSLIEQACSDIKRIQKAVNVCRTWFVYSEQSAIPAPKQFEPVFKALLNNLNFANAITHIWKLVKQINHDVSKQNLSGLKEHLSHLEWALNILGIGFKSIHTKLNVQLIKKWASLRKNGQLDKADEVRQKLIKKGLL
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_ECO45
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGGFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTNWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: YMX2_YEAST
Sequence: MTIAEITIRQKFSYPFLFGNVLGHPWPRNVPRKEIKMLLFRTANNSFPGFLLIFTRKRRNLPKQRDNEIPRTRALETYLRVFSAARKQREADATASFWRLVTSASRSHYHMWPIKRII
What are the official names of this protein?
Uncharacterized protein YMR082C.
Protein: RUXX_METBU
Sequence: MGNRPLDILNDALNTSVIVRLKGAREFRGVLQGYDVHMNLVLDEAEELKDGEIVRKIGGVVIRGDNVVYVSP
What are the official names of this protein?
Putative snRNP Sm-like protein.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
Protein: SYA_ENT38
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPNNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQYAWELLTGENWFNLPKERLWVTVYETDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGTAEEDGDRYIEIWNIVFMQFNRQIDGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFSTLIKSVAEVTGATDLSNKSLRVIADHIRSCAFLIADGVIPSNENRGYVLRRIIRRAVRHGNMLGAKDTFFYKLVGPLVGVMGDAGEELKRQQSQVEQVLKTEEEQFARTLERGLALLDEELSQLTGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRARESSGFGADYNAMIRVDSASEFQGYDRLELNAKVTALFVDGKAVDSISAGQDAVVVLDKTPFYAESGGQVGDKGELKGNGFSFAVSDTQKYGQAIGHIGKLASGSLKVGEGVQAEVDEARRERIRLNHSATHLMHAALRDVLGTHVAQKGSLVNDKILRFDFSHFEAMKPSEIRAVEDMVNAQIRRNLPIETNIMDLEAARAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRILSESGTAAGVRRIEAVTGEGAIASLHAESDQLHDIAQLLKGDSHNLGEKVRSALERSRQLEKELQQLKEQAAVQESANLSSKAVDIKGVKLLVSELAGVEPKMLRTMVDDLKNQLGSTIIVLATAVDGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVESWVSAKL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_PECCP
Sequence: MAEFNLEALNALPKAEQAAALAVVNGQLEQLSAQERVSWALENLPGDYVLSSSFGIQAAVSLHLVTQQRPDIPVILTDTGYLFPETYQFIDALTEQLKLNLQVYRATESAAWQEARYGKLWEQGVEGIERYNLLNKVEPMNRALSELKAKTWFAGLRREQSGSRGDLPVLAIQRGVFKFLPIIDWDNRTVYQYLKENGLSYHPLWDQGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_ONYPE
Sequence: MFSLHFVDEAFNEVFAGNGGHGIVAFRREKYVAFGGPAGGNGGKGGSVIFVGDKDETTLLKLKYQKHLKAPHGINGKNKGQNGANAPHLYVKVPLGTVFYTADNKFLGEILYDQQTLVIAKGGKGGKGNKALATFKNQAPSYAEKGDLGESFKIKTELKVLADIGLLGFPSVGKSSLISAISKAQPKVASYPFTTIKPHLGVVEVDGFSFVVADLPGLIANAHLGCGMGIQFLKHIERCRVLVHILSMESANPYQDFQTLNQELSQYNPQLLLKKQIIVTNKMDLPDALQKLTLLKQQIKDQPIIPLSLVSFDNLETLKYEMSSLLQNTPLEVAPNKNNDFKLYTLPDNQNTISVIKESDSVFVVSGKQVETFFHRTDFNNEEAVKRFNRILKKIGMEEQLQKQGAKPGDQVKICDRLFYFL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADB_HALSA
Sequence: MTDATTTDVLVLGSGIAGCGAALAAAREGASVLVATKAQQPADASTDWAQGGIATTRDDPESLKRDILAAGDGEADPEAVDALVGDAAAAVEDVLVDTLGVPFDGEEGFDYAREAAHSAARILHVDAATGHHILGPFLRHLDAHENVDMLEDAAALDLITDEGAVTGALLDRNPRTGDRAETGVPVFAGSTVLATGGIGDLYRRSTNPRGSTGDGVAMAALAGADVTDAEYVQFHPTAYDDADPFLVSEAVRGEGALLRNADGERFMPDYHEDAELAPRDVVARAVAAERDATGEVRLDVSPLAFAEEFPGLAEACADRGVDWETGIPVAPCEHFLCGGVAVDTVGRTSLDRLFAVGECARTGVHGANRLASTSLLEGLVWGLRAGETAAGDDRAPAPSEPPELRDRDPDLPDGFAAEKFRRLRRVMDEHVGLRRTGADLQRAQGVLRRLKGEVDSYARTRTSRDLYQLRNAAVVGLLIARAAGENPESAGCHHRSDEAAAEEAPDAGH
What is the function of this protein?
Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
What are the official names of this protein?
L-aspartate oxidase, LASPO, Quinolinate synthase B.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGRB_ECODH
Sequence: MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.