PharMolix/UniProtQA huggingface dataset:
Protein: PTH_ECOLU
Sequence: MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAKFFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPLGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPM6B_PONAB
Sequence: MKPAMETAAEENTEQSQKRKGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNASDHALLSEVIQLMQYVIYGIASFFFLYVIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQTNGTTGVEQICVDIRQYGIIPWNAFPGKICGSALENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF
What is the function of this protein?
May be involved in neural development.  Involved in regulation of osteoblast function and bone formation.  Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton.  May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake (By similarity).
What are the official names of this protein?
Neuronal membrane glycoprotein M6-b, M6b.
What is the protein family that this protein belongs to?
Belongs to the myelin proteolipid protein family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane. Note=Colocalizes with SERT at the plasma membrane.
Protein: SAR1_DEBHA
Sequence: MWLFDWFQDVLASLGLWNKHAKLLFLGLDNAGKTTLLHMLKNDRLATLQPTLHPTSEELAIGSVRFTTFDLGGHQQARRLWKDYFPEVNGIVFLVDAADPERFAESKAELESLFKIEELASVPFLILGNKIDASSAVGEMELKSALGLYNTTGKDTGKLPEGQRPIEVFMVSVVMRMGYGDGFKWLSQYI
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  SAR1 controls the coat assembly in a stepwise manner.  Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex.  These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase SAR1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DACA_LISM4
Sequence: MDFSNMSILHYLANIVDILVVWFVIYKVIMLIRGTKAVQLLKGIFIIIAVKLLSGFFGLQTVEWITDQMLTWGFLAIIIIFQPELRRALETLGRGNIFTRYGSRIEREQHHLIESIEKSTQYMAKRRIGALISVARDTGMDDYIETGIPLNAKISSQLLINIFIPNTPLHDGAVIIKGNEIASAASYLPLSDSPFLSKELGTRHRAALGISEVTDSITIVVSEETGGISLTKGGELFRDVSEEELHKILLKELVTVTAKKPSIFSKWKGGKSE
What is the function of this protein?
Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a signaling compound secreted into the host's cytosol where it triggers the cytosolic surveillance pathway (CSP), a host pathway of innate immunity characterized by expression of beta interferon (IFN-beta) and coregulated genes (Probable).  Overexpression increases export of c-di-AMP (PubMed:23716572).  c-di-AMP is a second messenger that mediates growth, cell wall stability and virulence (Probable).
What are the official names of this protein?
Diadenylate cyclase, DAC, Cyclic-di-AMP synthase, c-di-AMP synthase.
What is the protein family that this protein belongs to?
Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BARP_HALO1
Sequence: MSDSYVFSSPIIIHPGSDTLQAGLADEEHPGSIFPNIVGRHKLAGLMEWVDQRVLCVGQEAIDQSATVLLRHPVWSGIVGDWEAFAAVLRHTFYRALWVAPEEHPIVVTESPHVYRSFQLRREQLTRLLFETFHAPQVAVCSEAAMSLYACGLDTGLVVSLGDFVSYVAPVHRGAIVDAGLTFLEPDGRSITEYLSRLLLERGHVFTSPEALRLVRDIKETLCYVADDVAKEAARNADSVEATYLLPNGETLVLGNERFRCPEVLFHPDLLGWESPGLTDAVCNAIMKCDPSLQAELFGNIVVTGGGSLFPGLSERLQRELEQRAPAEAPVHLLTRDDRRHLPWKGAARFARDAQFAGFALTRQAYERHGAELIYQM
What is the function of this protein?
May be a dominant-negative inhibitor of eukaryotic actin polymerization.
What are the official names of this protein?
Bacterial actin-related protein, BARP.
What is the protein family that this protein belongs to?
Belongs to the actin family.
Protein: SSUH2_DANRE
Sequence: MSASPAANTFGASAPPANMFDTVPGYEGTLAGGGGGYLPPPMPSVPMPVPEQAPHPPDWHIPSISEERAREAFATYVSSNCCYSSGPVTDGVITNMQSFNTYRYRLETFTESRSTEWSQEPYSGQPVDAGVQPAPGPWQIAAQPPPFFQDQKQAIKVPFTSSIKNCHVCLGMGNKPCTTCAGAGNKVCWVCNGSGSRLNDERCSHCNGQGRENCSSCSGNGSSQCDTCHGKRQLIVFINLNVKWSTEKEDFVAQDLSGLKVEKLEKVSGKELFKDSQFMVYPVMGFPDASVAQASQRIVRDHQTKFAQTSRILQQRQTIELIPVTKVNYTWKGNPYVYYVYGNEFEVNAEDYPATCCCSVM
What is the function of this protein?
Plays a role in odontogenesis.
What are the official names of this protein?
Protein SSUH2 homolog, Protein ssu-2 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYR_ECOUT
Sequence: MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGNYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVAMPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME_AZOVD
Sequence: MNPVRKRRLFIVLAILAGVGAAVALALSALQQNINLFYTPSQIAAGEAPEGARIRAGGLVEKGSLQRDATSLAATFRVTDGVATVTVRYQGILPDLFREGQGIVALGRVDAGGMLQADEVLAKHDENYMPPEVSQALEKSGMLKHYENGKPGGAQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: CLP1L_HUMAN
Sequence: MWSGRSSFTSLVVGVFVVYVVHTCWVMYGIVYTRPCSGDANCIQPYLARRPKLQLSVYTTTRSHLGAENNIDLVLNVEDFDVESKFERTVNVSVPKKTRNNGTLYAYIFLHHAGVLPWHDGKQVHLVSPLTTYMVPKPEEINLLTGESDTQQIEAEKKPTSALDEPVSHWRPRLALNVMADNFVFDGSSLPADVHRYMKMIQLGKTVHYLPILFIDQLSNRVKDLMVINRSTTELPLTVSYDKVSLGRLRFWIHMQDAVYSLQQFGFSEKDADEVKGIFVDTNLYFLALTFFVAAFHLLFDFLAFKNDISFWKKKKSMIGMSTKAVLWRCFSTVVIFLFLLDEQTSLLVLVPAGVGAAIELWKVKKALKMTIFWRGLMPEFQFGTYSESERKTEEYDTQAMKYLSYLLYPLCVGGAVYSLLNIKYKSWYSWLINSFVNGVYAFGFLFMLPQLFVNYKLKSVAHLPWKAFTYKAFNTFIDDVFAFIITMPTSHRLACFRDDVVFLVYLYQRWLYPVDKRRVNEFGESYEEKATRAPHTD
What is the function of this protein?
Scramblase that mediates the translocation of glucosaminylphosphatidylinositol (alpha-D-GlcN-(1-6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol, GlcN-PI) across the endoplasmic reticulum (ER) membrane, from the cytosolic leaflet to the luminal leaflet of the ER membrane, where it participates in the biosynthesis of glycosylphosphatidylinositol (GPI) (PubMed:35344438).  GPI is a lipid glycoconjugate involved in post-translational modification of proteins (PubMed:35344438).  Can also translocate 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (phosphatidylinositol or PI), as well as several other phospholipids (1,2-diacyl-sn-glycero-3-phosphocholine, 1,2-diacyl-sn-glycero-3-phosphoethanolamine), and N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI) in vitro (PubMed:35344438).
What are the official names of this protein?
Lipid scramblase CLPTM1L, Cisplatin resistance-related protein 9, CRR9p, Cleft lip and palate transmembrane protein 1-like protein, CLPTM1-like protein.
What is the protein family that this protein belongs to?
Belongs to the CLPTM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL15_MYCBP
Sequence: MTLKLHDLRPARGSKTARTRVGRGDGSKGKTAGRGTKGTRARKQVPVTFEGGQMPIHMRLPKLKGFRNRFRTEYEIVNVGDINRLFPQGGAVGVDDLVAKGAVRKNALVKVLGDGKLTAKVDVSAHKFSGSARAKITAAGGSATEL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: TCF25_HUMAN
Sequence: MSRRALRRLRGEQRGQEPLGPGALHFDLRDDDDAEEEGPKRELGVRRPGGAGKEGVRVNNRFELINIDDLEDDPVVNGERSGCALTDAVAPGNKGRGQRGNTESKTDGDDTETVPSEQSHASGKLRKKKKKQKNKKSSTGEASENGLEDIDRILERIEDSTGLNRPGPAPLSSRKHVLYVEHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPECEQSSARQKASLLIQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEENVHEVLQAVDAGDPAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMANFHLNDLEAPHEDDAEGEGEWD
What is the function of this protein?
May play a role in cell death control.  Acts as a transcriptional repressor.  Has been shown to repress transcription of SRF in vitro and so may play a role in heart development.
What are the official names of this protein?
Transcription factor 25, TCF-25, Nuclear localized protein 1.
What is the protein family that this protein belongs to?
Belongs to the TCF25 family.
What are the subcellular locations of this protein?
Nucleus. Note=Some staining in the cytosol.
Protein: SYE_HALMA
Sequence: MDDELRDRITEAAETNALLNAVKHDSEAQVGAIMGPLMGENPEFREYGDEIPGVIAPVVERVNGMDAEERRERLAELAPEKLEELEAEDEGEDHPLPDLPSAEEYDTVRMRVAPNPNGPWHIGHARMAAVVGTYKQRYDGEFICRFDDTDPETKRPDLDAYDAILDAIDYLGFEPDDVVNASDRVETYYEYARKLIDKGGAYTCSCPQGEFSDLKNNGEACPHRDKDAETTRSEFEAMVDGEYDSGEMVLRVRTDITHKNPALRDFVAFRMVDTPHPREAAEQYRCWPMLDFQSGLDDHLLGVTHIIRGIDLQDSAKRQQFVYDYFDWEYPEVIHWGHVQVDEYDVPLSTSSIAELIEDGELAGWDDPRAPTVASLERRGIRGEAVVDAMIQLGTSTSNVDLAMSSIYSNNRDLIDDDSDRAFFVRDSDDHGGLVERQIVGGPDAGEPPLHPDYEERGRREIPVTSGVVVEGDDLPDHGDRIWLKGYGCVRHTRDAFEYTGDDIDAVREEGVDVIHWAPADGPALRLRTMDGDVSGVAEPGLRNYDTDDVVQFERIGFARLDKVADDSDTESVAYFTHP
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURR_ECO7I
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: RD23D_ARATH
Sequence: MKIFVKTLSGSNFEIEVKPADKVSDVKTAIETVKGAEYPAAKQMLIHQGKVLKDETTLEENNVVENSFIVIMLSKTKASPSGASTASAPAPSATQPQTVATPQVSAPTASVPVPTSGTATAAAPATAASVQTDVYGQAASNLVAGTTLESTVQQILDMGGGSWDRDTVVRALRAAFNNPERAVEYLYSGIPAQAEIPPVAQAPATGEQAANPLAQPQQAAAPAAATGGPNANPLNLFPQGMPAADAGAGAGNLDFLRNSQQFQALRAMVQANPQILQPMLQELGKQNPQLVRLIQEHQADFLRLINEPVEGEENVMEQLEAAMPQAVTVTPEEREAIERLEGMGFDRAMVLEVFFACNKNEELAANYLLDHMHEFEDQ
What is the function of this protein?
May be involved in nucleotide excision repair (By similarity).  Binds and presumably selects ubiquitin-conjugates for destruction.  Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains.  Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP) (By similarity).
What are the official names of this protein?
Ubiquitin receptor RAD23d, AtRAD23d, Putative DNA repair protein RAD23-4, RAD23-like protein 4, AtRAD23-4.
What is the protein family that this protein belongs to?
Belongs to the RAD23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PAND_HELP2
Sequence: MTFEMLYSKIHRATITDANLNYVGSITIDEDLAKLAKLREGMKVEIVDVNNGERFSTYVILGKKKGEICVNGAAARKVAIGDVVIILAYASMNEDEINAHKPSIVLVDEKNEILEK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM23_DANRE
Sequence: MDNSTPPPGGFKGGLGSIFGGGTPEYSNTELSGVPLTGMSPLSPYLNVDPRYLIQDTDEFILPTGANKTRGRFELAFFTIGGCCITGAAFGTLNGLRMGLSETRDMPWSKPRNVQILNMVTRQGASWANTLGSVALLYSVFGVAIEKARGAEDDLNTVAAGTLTGMVFKSTGGLKGVARGGLIGLAMSGLYALYNNWDHLKGKSPSHY
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (By similarity).  Plays an essential role in early embryonic development.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim23.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NUSB_THEFY
Sequence: MGGSRRRGSRHKARVRAVEILYEAEVRGVPVSEVIERRRAQTEPPINEFTEQLATRVDEHRARIDELLETYAIGWTLDRMPVVDRNILRIGVYELLWADDIPDGVAIAEAVAMAKELSTDESPVFVNGLLSRLMEKKPSLSL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RL11_CALS8
Sequence: MAKKVLTQIKLQIPAGKATPAPPVGPALGQHGVNIMQFCKEFNERTAKDAGLIIPVVITVYSDRSFTFITKTPPASVLLKKAAGIESGSPKPNKQKVATLKRDVIRKIAEQKMPDLTAATLEAAMRTIEGTAKSMGIVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: Y1636_ARCFU
Sequence: MEKLAAKVLENFDFLKKLLRDRAECGESEITIYDDPVTIVVKRDRIDFFINEEYHGSVGVGFNTLSDEIREEARLWLEGLAGMKFKRYAVRR
What are the official names of this protein?
Uncharacterized protein AF_1636.
Protein: GUND_ACET2
Sequence: MSRMTLKSSMKKRVLSLLIAVVFLSLTGVFPSGLIETKVSAAKITENYQFDSRIRLNSIGFIPNHSKKATIAANCSTFYVVKEDGTIVYTGTATSMFDNDTKETVYIADFSSVNEEGTYYLAVPGVGKSVNFKIAMNVYEDAFKTAMLGMYLLRCGTSVSATYNGIHYSHGPCHTNDAYLDYINGQHTKKDSTKGWHDAGDYNKYVVNAGITVGSMFLAWEHFKDQLEPVALEIPEKNNSIPDFLDELKYEIDWILTMQYPDGSGRVAHKVSTRNFGGFIMPENEHDERFFVPWSSAATADFVAMTAMAARIFRPYDPQYAEKCINAAKVSYEFLKNNPANVFANQSGFSTGEYATVSDADDRLWAAAEMWETLGDEEYLRDFENRAAQFSKKIEADFDWDNVANLGMFTYLLSERPGKNPALVQSIKDSLLSTADSIVRTSQNHGYGRTLGTTYYWGCNGTVVRQTMILQVANKISPNNDYVNAALDAISHVFGRNYYNRSYVTGLGINPPMNPHDRRSGADGIWEPWPGYLVGGGWPGPKDWVDIQDSYQTNEIAINWNAALIYALAGFVNYNSAQNEVLYGDVNDDGKVNSTDLTLLKRYVLKAVSTLPSSKAEKNADVNRDGRVNSSDVTILSRYLIRVIEKLPI
What is the function of this protein?
This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
What are the official names of this protein?
Endoglucanase D, EGD, Cellulase D, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
Protein: PUR5_CLOP1
Sequence: MLTYKEAGVNIEEGYRSVKLIKEYAKKTMSEYVLNGLGSFAGMVELPEGYKKPVLVSGTDGVGTKLDIACKKRKFDTVGIDCVAMCVNDILCHGAKPLFFLDYIACGKLEAEVSSDLVKGVAEGCIESQCSLIGGETAEMPGMYKEGDYDIAGFAVGIVDKDKIINGKDIKSGDKLIGIASSGVHSNGYSLIRKVFKNLDEDFNGKAIWEELLTPTKIYVKPVLSLLEKFNIKGMAHVTGGGFYENLPRMLSKEGLSIVINKNSYEIPEIFKKLMELGVKEEEMYNTFNMGIGFVLCVEEDEVEEVLKELSKQGEKAFEIGYINAGGEGVCIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_METM5
Sequence: MDLRKKIRIVEDFPIEGISFKDVTPILKDPKAMKHTTKEITKYLEDKNVDVIVGPEARGFLFGIPVAHELDIGFVPVRKPGKLPYKTFSVDYALEYGADSLEIHSDGIEKGQNVAIVDDLLATGGTVLGVSKLVEKLGGHVSALNFVIELTELKGRDKLKGYGIQSLVKYDL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_CHESB
Sequence: MNKPVEPNSFRTGPDEQGMFGIFGGRFVAETLMPLILELEEHWNAAKNDPAFKAELQQLGAHYTGRPSPLYFAERLTEHLGGAKVYFKREELNHTGSHKVNNCLGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMRLLGAEVKPVTSGHGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGQETKEQILAAEGRLPDMLVAAVGGGSNAIGLFHPFLDDKGVAMVGVEAGGKGLEGDEHCASLTAGSPGVLHGNRTYLLQDSDGQIKEGHSISAGLDYPGIGPEHSWLKEAGRVEYVPIMDHEALEAFQLLTRLEGIIPALEPSHALAEVIKRAPKMGKDQIIVMNLSGRGDKDIFAVAKHLKMDV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: YL483_MIMIV
Sequence: MYDILQPELWVKIIDYSGEINLLLTDKNFFELFNLIDTKVDVVEYIVKNNLIDALKYFILLKKLRHPIMEKNIVTIKSLNKCLIKSCKKNKLNIIKYLVSLGADIKAGDDCAVQLASQNGHLEVIEYLVAQGANIRADNDYAVIWASRNGYLDIVKYLVSQGADIRANNDYAVRWASRNGHLKVVKYLVSLGANIRTENDYAIKYASENGYLRIVEYLVSQGADIRADNDYAVGLASSNGHFEVVEYLVSQGANIRVDNDYAVRLASSNGHLEVVKYLVSLRANIRARCDFAIKWSSSNGHLEVVKYLVSQGADIRSQNDYAVRYASTNGHLEVVKYLVGQGADIRTGDDYAVRWASRGGCLEVVKYLVDQGANIRAKDDYAVKWASEKGHLEIVKFLISQGAVLTKN
What are the official names of this protein?
Putative ankyrin repeat protein L483.
Protein: RL4_GLUDA
Sequence: MDYEIKTLDNGSAGTAVLPDEIFGVTPRADIMARVVHWQLAKRRAGTHKVKGMGEVSGTTKKPYRQKGTGSARQGSLRAPQYRTGGAVHGPVVRDHGYDLPKKVRRLGLISALSQKAAEGKLVVLDAATASGRTSELAAKVKALGWKSALIVDATVEENFGRAARNLPKIDALPTIGANVYDILNHDVLAITRAGVEGLKERLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y764_STRPG
Sequence: MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHAARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKFNTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYASPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMNDIGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTLAKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKELGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK
What are the official names of this protein?
UPF0371 protein SpyM50764.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: COQ5_RAT
Sequence: MAAPRSCVLWSYCGHGWSRLAGDCRLPGFRRSWLGATLSARSLSQEKRAAETHFGFETVSEKEKGGKVYQVFQSVARKYDLMNDMMSLGIHRAWKDLLIRKMHPLPGTQLLDVAGGTGDIAFRFLSYVQTQHERKQRRQLRTRQNLSWEEIARKYQSKEDPLGGSLVMVCDINREMLKVGKQKALARGHTAGLAWVLGDAEELPFDDDRFDVYTIAFGIRNVTHIDRALQEAHRVLKPGGRFLCLEFSQVNDPLISRLYDLYSFQVIPVIGEVIAGDWKSYQYLVESIRKFPNQEEFKDMIEDAGFQKVTYESLTSGIVAIHSGFKL
What is the function of this protein?
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: H32_XENLA
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.