PharMolix/UniProtQA huggingface dataset:
Protein: APOC1_OTOGA
Sequence: MRLMLSLPVLVLVLAMVLEGPAPAQGTMDLDFTRHLKEFGNTMGDKAREVIDRIKQSDIPAKTRNWFSETFQKVKEKLKI
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3342_CLOBB
Sequence: MRFVIVTGLSGAGKTQATRSLEDLGYFCVDNLPPKLINKFAELCSQGDGKIDKVALVIDIRGGVFFDDLFETLNYLKENEFKYEILFLDASDEVLIKRFKESRRSHPLSPDGRVLNGIIQERSKLREIKDRADIIIDTSKYAIRDLREKMNEHYGDNIESEKQLSITVLSFGFKYGIPVDSDLVFDVRFIPNPFYIPELKQYSGNDKSVKDYVLKQEETITFVEKLQDMLEYLVPNYIKEGKRQLIISIGCTGGRHRSVAIANEIYERLNKGNYKAKIEHRDVGEDLHRGEKKL
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein CLL_A3342.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: SECA_BARBK
Sequence: MVSLSIIARKLFGSARESRIKRLRQKALQISALEEHFQKLSDGELCQKTDEFRQRLTDGETIDSLLPEAFATVREAAKRVYNMRPFDVQLIGGMVLHNRGIAEMRTGEGKTLMATLPVYLNALEGKGVHVVTVNDYLANRDAETMGKIYSFLGLTTGVILHDLDTNARRAAYACDITYATNNELGFDYLRDNMTFDRSQMVQRGHHYAIIDEVDSILIDEARTPLIISGPLEDRTDFYNLVNTFIPNLTPEDYEIDEKQKTTTFTEIGTEKIEKMLEQAGHLKNDSLYDIENVAIVHHVNNALKAHKLFVRDKDYIVRNGEIVIIDEFTGRMMPGRRYSEGLHQALEAKEHVAIQPENQTLASITFQNYFRMYEKLSGMTGTATTEAEEFSNIYGLEVVEIPTNLPVQRLDEDDEIYRTTEEKYRAIVRDIRQAHEKGQPILVGTTSIEKSEQLAERLRKEGITDFKVLNARYHEQEAYIVAQAGVPGALTIATNMAGRGTDIQLGGNIEMRIRQELQDIPEGSERTAKIEKIKQDVQKLKEKSLAAGGLYVLATERHESRRIDNQLRGRSGRQGDPGRSKFFLSLQDDLMRIFGSDRMDSILQKLGLKENEAIIHPWINKALEKAQKKVEARNFEIRKNLLKYDDVMNDQRKVIFEQRMEIMNAENLTDMMIEMRNDVIEDLIETHIPSGTYSEKWNAKALQSELSQCFNLELPIEEWVKEDGIAEQQILERILDAVTKFENERTEHYSPEMMVYFHKAILLKTIDMLWREHLINLDHLRSVIGFRGYAQRDPLNEYKTEAFELFQTMLKNLRRDVVSKLMSFEIVQHPLESTMPQEMYAEHSTSRNIDKKDGILWAQMQNNTEVSDPIKRDPGDSSTWEKVGRNELCPCGSSKKYKHCHGSFIPKMDG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: Y570_STRGC
Sequence: MDPKKIARINELAKKKKTEGLTAEEKVEQAKLREEYIEGYRRSVRHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPNS
What are the official names of this protein?
UPF0291 protein SGO_0570.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_PARXL
Sequence: MKQPSALSALVEALRALPGVGPKSAQRMAYHLMQHDRDGAEKLGRSLLFATEHLQHCEKCNTFTEAQICEVCLDEERDPTLLCVVETPADQIMLEQTMTYRGLYFVLMGRLSPLDGIGPKEIHFDRLVRRASDGVVKEVVLATNFTNEGEATAHYLGQTLKARGLAVTRLARGVPVGGELEYVDAGTIARAMLDRRSM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: YXJN_BACSU
Sequence: MAMSPYIFIVLILIILSMYRERTVKPGKLLIIPLLLLWGVSASFQPAYFHSVLHVAISGILLLIGLACGFGIGKMVNVRIHPETGKVTSRGSLGSVILILVILSLRMAARTWLPESNEMFIAIIHSMFFVPLGTITARNIMLYKAYRRLTAGKVSIQ
What are the official names of this protein?
Uncharacterized protein YxjN.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DXR_DESHY
Sequence: MKRLTILGSTGSIGTQTLDIVRQNPEQLEVFALAAGKNVQEIELQAREFKPRIIGLMEEKAARELKQRVADLDIEVVSGMEGLLRTVTDEVPDTVVTAISGRIGLEPTMEALKVGKDIALANKETLVAGGDLVMGTAQRLGRTILPVDSEHSAIFQCLEEDPRTLDKIILTASGGPFRGWSEEQLQEVTPERALQHPNWAMGAKITIDSATMMNKGLEVIEAHHLFHMEYDQIDVLIHPQSVIHSMVQYCDGSVLAQCGRPDMRLPIQYALTYPTRWPNPFERLDLRGKTLTFFDPEDYDFPALKLAYACGKRGGTLPAVMNAANEVAVHAFLARRVAYLEIIGLVDKVCSEHDVLDATDLETILNADHWARIRTEELIHG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: CRU1_RAPSA
Sequence: MVKLAHLLVATFGVLLVLNGCLARQSLGVPPQLGNACNLDNLDVLQPTETIKSEAGRLEYWDHNHPQLRCAGVSVSRLIIEQGGLYLPTFFSSPKIAYVVQGMGISGRVVPGCAETFMDSQPMQGQGQQGQQGQQGQQQQGFRDMHQKVEHVRHGDVIAITAGSAHWIYNTGDQPLVIVCLLDIANYQNQLDRNPRTFRLAGNNPQGGSHQQQQQQQQNMLSGFDPQVLAQALKMQLRLAQELQNQQDNRGNIVRVKGPFQVVRPPLRQQYESEQWRHPRGPPQSPQDNGLEETICSMRTHENIDDPARADVYKPNLGRVTSVNSYTLPILQYIRLSATRGILQGNAMVLPKYNMNANEILYCTQGQARIQVVNDNGQNVLDQQVQKGQLVVIPQGFAYVVQSHGNNFEWISFKTNANAMVSTLAGRTSALRALPLEVITNAFQISLEEARRIKFNTPETTLTHARGGQPQLIEEIVEA
What is the function of this protein?
This is a seed storage protein.
What are the official names of this protein?
Cruciferin PGCRURSE5, 11S globulin, 12S storage protein.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: FUND1_MOUSE
Sequence: MASRNPPPQDYESDDESYEVLDLTEYARRHHWWNRVFGHSSGPMVEKYSVATQIVMGGVTGWCAGFLFQKVGKLAATAVGGGFLLLQVASHSGYVQIDWKRVEKDVNKAKRQIKKRANKAAPEINNIIEEATDFIKQNIVISSGFVGGFLLGLAS
What is the function of this protein?
Acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control.
What are the official names of this protein?
FUN14 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the FUN14 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: PSAI_COFAR
Sequence: MITFSFPSIFVPLVGLVFPAIAMASLSLHVQKNKII
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TILS_BUCBP
Sequence: MLKDFIKNTNILNILLAYSGGIDSTFLLYQLLKLKKNNLNFTFRAIHINHQLHPDSEKWSDHCKKICINHNIPIIIKKITINSNKNRIEEIARKKRYQAIYKIIKPKEVLATGHNLNDQCETMLLALKRGSGITGLSSMSYKLNTIYKIKIVRPLLKISREDIKTWIYKHKIHWIEDTSNNDTKHDRNFLRLNIIPKLKNRWPYFEKNCSRSIEILNIEKKILKQEIKKKLNKYLVLNSILNISNFRYIDKNICSIILRHWIKINQNTMPTFKIVKEIYNKVIFSKIDSQPKIIIKNYQIRRYNNHLYWTKKIPRIENIILIWNNTQKKLTLPFQLGNIVQNDFGTTLPHPNNNETINIRFYTSHKVLITKNTKHKKLKTIFKEYKLPPWYRKKIPLIFYNNKFICALGLFVSNTHKKSNNEKNLKLSWISSIHNIIV
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMRX_METMA
Sequence: MSFQRIAWGITGAGHFLDRSYQVFKELKLRNPELSVNTYVSRAAEEVLRMYGLEQKLVKISGGDYLEEIFRESEQGSSSPKVGRFALDRYDALFVTPATSNTVSKIAYGIADSLVTNAVSQAVKGRVPVFVVPVDIEGSIISEMPYNIDRKQCKHCETCPPRENCPHEAISEKNGVTDQIDLLKCKGCGICKELCPYNAIKGGPVEVLVRDVDMRNVEIVKSLQGITVLESPEAILELF
What is the function of this protein?
Involved in the biosynthesis of tetrahydromethanopterin, a coenzyme used in methanogenesis.  Catalyzes the reduction of dihydromethanopterin (H(2)MPT) to tetrahydromethanopterin (H(4)MPT).  Ferredoxin may serve as an electron donor.
What are the official names of this protein?
Dihydromethanopterin reductase (acceptor), H(2)MPT reductase.
Protein: MGSA_ENTFA
Sequence: MKIALIAHDRKKTLMIKLATAYKHILEKHELYATGTTGMKVMEATGLPVHCFKSGPLGGDQQIGAMISEDNIDLVIFLRDPLSAQPHEPDVTALIRLSDVYEIPLATNIGSAEILLRGVEAGFADFREVIHEGDRRPLAF
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: BCHB_PELPB
Sequence: MRLAFWLYEGTALHGISRVTNSMKGVHTVYHAPQGDDYITATYTMLERTPQFPGLSISVVRGRDLAQGVSRLPSTLQQVEHHYHPELIVIAPSCSTALLQEDLHQLAAHSGLPQEKILVYALNPFRVSENEAADGLLTELVKRFASPQEKTAQPSVNLLGFTSLGFHLRANLTSIRRMLQTLGIAVNVVAPWGASIDDLRKLPAAWLNIAPYREIGSTAAEYLADAFAMPALYEAPIGVEPTLAWLRSLIEKLNAAGAERGVAPIVMPQLNAFSLDGLSAPSGVPWFARTADMESFSNKRAFVFGDATHTVALVKFLRDELGMQIIGAGTYLERHADWVRKELEGYLPGALIVTDKFQDVAQIIDDQMPDLVCGTQMERHSCRKLDVPCMVVCPPTHIENHLLGYYPFFGFDGADVIADRVYLSCKLGLEKHLIDFFGDAGLEYEEPEVSAPSEEPVALSVAPNDHPSPEAAAEAVVIAEEGEMKWSDEAETMLKKVPFFVRKKVRKNTETFARASGASMISVDVFRQAKESLGG
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: ACL1_NEUCR
Sequence: MPSATTASTNGANGASASPAPGNLSANDNIRRFAAPSRPLSPLPAHALFNDKTRCFVYGLQPRAVQGMLDFDFICKRSTPSVAGIIYTFGGQFVSKMYWGTSETLLPVYQEVPKAIAKHPDVDVVVNFASSRSVYSSTMELMEYPQIKTIAIIAEGVPERRAREIAYVAKKKGITIIGPATVGGIKPGCFKIGNTGGMMDNIVASKLYRKGSVGYVSKSGGMSNELNNIISQTTDGVYEGVAIGGDRYPGTTFIDHLLRYQADPDCKILVLLGEVGGVEEYKVIDAVKQGIITKPIVAWAIGTCASMFKTEVQFGHAGAFANSQLETAATKNKSMREAGFYVPDTFEDMPALLKQVYDKLVADGTIVPAPEPVVPKIPIDYSWAQELGLIRKPAAFISTISDDRGQELLYAGMPISDVFKEEIGIGGVMSLLWFRRRLPDYAAKFLEMVLMLTADHGPAVSGAMNTIITTRAGKDLISSLVAGLLTIGSRFGGALDGAAEEFTKAFDKGLSPREFVDTMRKQNKLIPGIGHRVKSRNNPDLRVELVKEYVKAKFPSTKLLDYALAVESVTTSKKDNLILNVDGCIAVCFVDLLRNCGAFSTEEAEDYLSMGVLNGLFVLGRSIGLIAHYLDQKRLRTGLYRHPWDDITYLLPSLQQPGPPGTEGRVEVQI
What is the function of this protein?
Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols.
What are the official names of this protein?
Probable ATP-citrate synthase subunit 1, ATP-citrate (pro-S-)-lyase 1, Citrate cleavage enzyme subunit 1.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX_I45A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKVETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELGDPNALLKHRFEIIEGRDRTMAWTIVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKSQEQCASSPTKVSRRTSPALKILEPMWMDSNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: THIM_PYRFU
Sequence: MISVGEALAKVRERKPLVHNITNFVVMNTTANALLALGASPVMAHAEEELEEMVRIADSVVVNIGTLDKFWINSMIKAAKLAKEYGKPLVLDPVGAGATRLRTKTALEVLKIGATIVKGNFGEISALLGEEGKTRGVDSSTYDPERAKELALAVAEEFSTIVAVTGKVDYVSDGKRVYAVYNGHELLGRVTGTGCIVAALTGAFVAVNDPLTSAVSSLVVFEVAAEKAAEEAKAPGTFHAKLYDWLYLLTPEDVERLKKIEVVKV
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: CMOB_VIBA3
Sequence: MFNFANFYQLIAQDTRLQPWLNVLPQQLTDWQNAEHGDFDRWLRALNKIPQGVPDQVDLKNSVTIGSSTPFHTGELKKLESLLKTFHPWRKGPYTVHDIHIDTEWRSDWKWDRVLPHISPLKNRSVLDVGCGNGYHMWRMLGEGARLTVGIDPSHLFLVQFEAIRKLMGDDQRAHLLPLGIEQLPKLEAYDTVFSMGVLYHRRSPLDHLIQLKDQLVSGGELVLETLVIEGDENAVLVPVDRYAQMRNVYFFPSARALKRWLEQVGFEDVRIVDENVTTIGEQRTTDWMTHNSLPDYLDPNDPSKTVEGHPAPRRAILVATKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: GCH1_BACAA
Sequence: MAKVNLEQIEHAVRLILEAIGDDPNREGVLDTPKRVAKMYAEVFSGMHEDPKEHLHKVFGEDHEELVLVKDIPFYSMCEHHLVPFYGVAHVAYIPQGGKVTGLSKLARTVDTIARRPQLQERITSTVANSIMEVLEPHGVMVVVEAEHMCMTMRGVKKPGAKTVTTAVRGVLENDAAARSEILSFIKTK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: YRAN_ECO7I
Sequence: MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVNERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: XLNR_MAGO7
Sequence: MLSNPLHRFSGYHAMPSNTLMSNGHMSQGHLHNNGLDGLGQSSHYALQQLQQHVGVHNPHLARAAPHMKHHRQHPYGPAVRTAGIAGPIRRRISRACDQCNQLRTKCDGNHPCAHCIEFGLGCEYIRERKKRGKASRKDLAQQAAAQAATTGSSSGQKSPTHSANTTKKDDQKVDGGSSTGNAPNSEQHSPDDKDLDNDAMQRSQRMGSMDSLDEMDHQGHISGHHHQQAALDREHHTMSNPSALDPNSYGGVHNGYERQGGMGTATSHIMGGAAHGGYGSQGGMSSYPELPYLQTQSPTGYSGGGASYRIGTSPLSAYPLSGETASPGWGLPIPSPPASHGQYHSQHMQQQSSASYGAGTSGGLASGHPQHLRYPVLDPLVPHLGNIIPLSLACDLIDLYFASSSSAQVHPMSPYVLGFVLRKRSFLHPSKPRLCQPALLASILWVAAQTSDAPFLTSVPSARGKICQKLLELTVSLLKPLIHTPSGDVSPVSSPVIDGAALGGLGVAMPGSISMEALSGETGAFGAAGTLDDVVTYIHLATVVSASEYKGASLRWWNAAWSLARELKLGRELPQNAPSAMSDTAGNERNDNDDTTEALGGGPNVITDEEREERRRIWWLVYIVDRHLALCYNRPLFLLDIECDGLLQPLDDTAYQNGEFRPHQVVTDPDMLGEDRRSSQKSETALIRGPSFECTGHGIFGYFLPLMTILGEIVDLNHARNHPRFGINFRSHSEWDEQTSEIARHLELYEQSLRRFEQQHLSAAAQAQAQAADAAKAAAAAQAQAHAQAQAQQTSSDDSAISADNISVTDVGTPSALSVHSVAHSAHTTSSSRLTESDVQTRIVLAYGTHVMNVLHILLTGKWDPINLLDDNDLWISSQGFITATGHAVDAAEAIGSILEFDPGLEFMPFFFGIYLLQGSFLLLLIADKLQSEASPSVVKACETIIRAHEACVVTLNTEYQRNFSKVMRSALAQVRGRVPEDLGEQHQRRRELLALYRWTGDGTGLAL
What is the function of this protein?
Transcriptional activator of the pentose catabolic pathway (PCP).  Involved in the induction of a variety of PCP enzymes during growth on D-xylose.  Has no effect on cellulolytic and xylanolytic enzyme activities.
What are the official names of this protein?
Xylanolytic transcriptional activator xlnR homolog, Xylanase regulator 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the xlnR/xlr1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UDG_ECO11
Sequence: MKITISGTGYVGLSNGILIAQHHEVVALDIVPTKVEMLNQKKSPIVDKEIEEYLATKQLNFRATTDKYDAYRDGTYVIIATPTDYDPKTNYFNTSSVESVIRDVVDINPNAVMVIKSTIPVGFTNLLKERLGIDNIFFSPEFLREGRALYDNLHPSRIVIGERSERAGRFAALLQEGAVKKDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYAESLGLNSRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYASVPNNIIGAIVDANRTRKDFIADSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGVPVIIYEPVMVEDEFFHSRVVRDLTAFKNEADIIISNRMTSELADVADKVYTRGLFGSD
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: NPD1_CALS4
Sequence: MDFKILKEKLPQSNLTVVLTGAGISKESGIPTFRGEDGLWKKYNPEELATPWAFQRNPALVWEWYDYRRRIISKAKPNKCHLLIAEFEERFKNVRVITQNVDGLHEAAGSTNVIELHGNIWKVKCTKCDFRGINREVPLSKIPPECPKCGSIVRPDVVWFGEPLPSDKLTEAMELSQRADLFIVIGTSLMVQPAASLPFLALERGAFVVEVSPEETPLSRKAHLFFQMGAVEFAMKFEEKEG
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase 1, Regulatory protein SIR2 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG3_BOTF4
Sequence: MNFLHSTLDRLREFTPVSNTSTFRTNGQITPEEFVAAGDYLVFKFPTWSWADASPTSKRANYLPAGKQFLVTRGVPCHRRLDDDFAGDAGHDETVVRDGEDFRGDGPHSPGDDEDGWLRTGGLAASQEARVRDVRTVDESGEMGEREDDEDDIPDMEDDDDDDEAIIRDPKADNASSSRRTYTIYIAYTPYYRTPRLYLSGYLSSSQPLPPHLMMEDIVGDYKDKTVTLEDFPYFSNNIKMASIHPCKHASVMKTLLDRADAALKLRREKQRQGKAVPGSKDTGMEGLVDDFEKTKIGDKKAVLEGLKAGGNGNDEWEVLQHDQDFANEEEEVAIRVDQYLVVFLKFMASVTPGIEHDFTMGV
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (PubMed:29417220).  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity).  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8.  The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE) (By similarity).  This step is required for the membrane association of atg8.  The formation of the atg8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt) (By similarity).  The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).  Required for normal mycelial growth and conidiogenesis, and regulates sclerotial formation (PubMed:29417220).  Plays an essential role in pathogenesis (PubMed:29417220).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme atg3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_STRPS
Sequence: MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKEELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKWINDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANKLLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDKQYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX9_RHOJU
Sequence: KEGYPVDWGNCKYECMSDEYCKDLCADRKATSGYCYKLNWSCYCKGLPDDSPIKTPGKCRSGR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Putative alpha-neurotoxin RjAa9.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LJ01_HUMAN
Sequence: PSRLLLQPSPQRADPRCWPRGFWSEPQSLCYVFGTGTKVTVL
What is the function of this protein?
J region of the variable domain of immunoglobulin lambda light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin lambda joining 1.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: COAD_BURP1
Sequence: MVVAVYPGTFDPLTRGHEDLVRRASSIFDTLVVGVADSRAKKPFFSLEERLKIANEVLGHYPNVKVMGFTGLLKDFVRANDARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVEKWLTEKVAAMAQGPSA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_LEGPH
Sequence: MRHSPRKRFGQNFLQDKYIINEILRAINPLADDNMLEIGPGLGALTQPLLQKLNQLTAIEIDTDLQSYLTCLPASQGKLNLIPADALTVDFCQFGPHLRVVGNLPYNISTPLLIYLLKFITCIDDMHFMLQKEVVERIAAAHGTKAYGRLSVMLQYHCEVEYLFDVPPEAFEPRPKVDSAIVRLTPYRVSPFESVNTEKLENIVAKAFAMRRKTLTNNLKGIISLSQLNDLGIDGGKRPEQISVAEYVQLAKFISN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.