PharMolix/UniProtQA huggingface dataset:
Protein: DAPB_BURM7
Sequence: MSSMKIAIAGASGRMGRMLIEAVLAAPDATLAGALDRTGSSQLGQDAGAFLGKQTGVALTDDIERVCAEADYLIDFTRPEGTLAHLDAALRHDVKLVIGTTGFSEPQKAQLRAAGGKIALVFSANMSVGVNVTMKLLEFAAKQFAQGYDIEIIEAHHRHKVDAPSGTALMMGETIAAATGRTLDDCAVYGRHGVTGERDPSTIGFSAIRGGDIVGDHTVLFAGIGERIEITHKSASRVSYAQGALRAARFLAGHQAGFFDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKTB7_DABSI
Sequence: MSSGGLLLLLGLLTLWAELTPISGHDRPTFCNLAPESGRCRGHLRRIYYNLESNKCKVFFYGGCGGNANNFETRDECRQTCGGK
What is the function of this protein?
Serine protease inhibitor that inhibits trypsin.
What are the official names of this protein?
Kunitz-type serine protease inhibitor 7, BPTI-7, Trypsin inhibitor 7, Trypsin inhibitor B7, Trypsin inhibitor C7.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPP_COXBN
Sequence: MSVLVPMVVEQTSRGERAYDIYSRLLKDRVIFLVGQVEDHMANLAIAQMLFLESENPNKDINLYINSPGGAVTSAMAIYDTMQFVKPDVRTLCIGQAASAGALLLAGGAKGKRHCLPHSSVMIHQVLGGYQGQGTDIQIHAKQTQRVSDQLNQILAKHTGKDIERVEKDTNRDYFLTPEEAVEYGLIDSIFTERP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB_CHESB
Sequence: MNNEHAEVMEMHMPTEKIVGQTDLYSIKSSTVRTPDAMPRPIRVKAREVNVFYGSKQALFDVSIDVPERAVTAFIGPSGCGKSTFLRCFNRMNDTIEGSKVTGRIELDGADIYDGSIDVVELRARIGMVFQKPNPFPKSIYENVAYGPRIHGLASAKGDLDRIVETSLQKAGLWNEVKDRLHEPGTGLSGGQQQRLCIARAIAVSPEVILMDEPCSALDPIATAKVEELIDELRENYTIVIVTHSMQQAARVSQRTAMFHLGYLVEEGPTDKMFTNPEEKRTQDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YACG_YERPS
Sequence: MESEQIQVNCPTCGKVVIWGEQSPFRPFCCKRCQLIDLGEWADEEKRIPSDTELSDSDEWSEEDPLKH
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: Y708_METS3
Sequence: MSDLDEIRRKRMAELEARQAAAQGQMQQQAQQQMQQQEAQRQFEEQKKALIAQILTTEARSRLANLKLTKPELVNQIEIQLIQSAQAGSLRGKVTDEQLKVLLRQIAGQKREIKITRK
What are the official names of this protein?
DNA-binding protein Msm_0708.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: RL24_HAMD5
Sequence: MAMKIRCNDQIIVLTGKDKGKRTKIKKILKNGKVILEGVNLVKKHQKPVPAQNQPGGIIEKEAPIDFSNVAIFNEDTGKADRIGFKYENGKKVRFFKSSGKAIAKINKS
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SYV_FERNB
Sequence: MEIGTRYDPKNIEMKWYKHWLEKKYFTPRGAGPKYSIVIPPPNITGKIHMGHALNITIQDILSRYKRMKGFDVLWLPGEDHAGIATQTAVERYLSTQGKSRRDFSRDEFLNIVWNWANKYRQEIKNQIMSIGASVDWTRERFTLDEGLSKAVRKVFVDMYKKGLIYKGKYIVNWCHRCGTVLSDEEVDYHEEEGALYHIKYPIKGEDDYIIIATTRPETMLGDTAVAVHPSDERYRKYVGKIAILPLVGREIPVIADNYVDPSFGTGALKVTPAHDTNDYLIGQRHNLPFVDIFDENIVINENGGKFKGMTAEQARKAVVEELEAQGYLVKIEKMKHSVGRCYRCDTVVEPRLMDQWFVSMKPLAKRAIEAVENGEVTFIPDRWKKVYLNWMYEIRDWCISRQLWWGHRIPVWQCQDCGHYNVSENEPVKCEKCGSTNLKQDEDVLDTWFSSALWPFSTMGWPEKTPDLERYYPTDVLVTGFDIIFFWVARMIMMGYEFMDEKPFKEVYIHQLVRDKYGRKMSKSLGNGIDPLEVIDEYGADPMRFTLAILAAQGRDLKLDVRFFDTYKKFANKIWNATRFVLMNLEDFEKVDIKLSKLKLSDKWILSRLQKTIQKISEALDSYDFNIAANEIYNFFWDELCDWYIEAVKNRLKTEERKVVQNVLVYVLDMSLRLLHPFMPFLTEELWTKLPTSGESIVVAQWPEIEENFIDENSEKRFMQLMNIIRGIRNIRAEVNVPQSTKVKTFVKGTLTDEEQEYIKFLGNVESIEFVEKRPELSATAYISLENEVYVSLGTLIDVKSEVERLRKKVEKLKSDMEKFAKKLEDENFLKNAPEDIVEETKEKQRLFQEQIARIEQIISDLEAKA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y178_UREPA
Sequence: MQNLNNKQKTLIIFLGIITFGIFIIYFFTKAKKVSQIRNTHLIVSSNIPFSLNDFYNCIGSKNNLVNVDATINTLKIELKEINALNNEKLKVLGAKGIMCNQTKISIIFGDFCLELKELIKKDLFS
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
What are the official names of this protein?
Putative phosphotransferase enzyme IIB component UU178, Putative PTS system EIIB component.
What is the protein family that this protein belongs to?
To M.genitalium MG129 and M.pneumoniae MPN268.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: OCRL_HUMAN
Sequence: MEPPLPVGAQPLATVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEED
What is the function of this protein?
Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2 (PubMed:7761412, PubMed:15474001, PubMed:9430698, PubMed:10764818).  Able also to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate (PubMed:7761412, PubMed:25869668).  Regulates traffic in the endosomal pathway by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with endosomes (PubMed:21971085).  Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976).  Acts as a regulator of phagocytosis, hydrolyzing PtdIns(4,5)P2 to promote phagosome closure, through attenuation of PI3K signaling (PubMed:22072788).
What are the official names of this protein?
Inositol polyphosphate 5-phosphatase OCRL, Inositol polyphosphate 5-phosphatase OCRL-1, OCRL-1, Lowe oculocerebrorenal syndrome protein, Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
Protein: RHBGB_XENLA
Sequence: MTSYSTNMRIKLPLFCLLLQFITIILFAVFVRYDHESDARGWHEELNNHSSSNADNDFYYRYPSFQDVHVMIFIGFGFLMTFLKRYGFSSVAFNFLIAAFGLQWSTLIQGFFHGFHDGKIHVGIESMINADFCTGAVLISFGAVLGKTSPVQLIIMTLVEVTLFGINEYIILNIVGAKDAGGSMTIHTFGAYFGLIVSRVLYREDLEKSRQREGSVYHSDLFAMIGTIYLWMFWPSFNSAVTAHGDDQHRTVMNTYYSLAACTLATFGFSALLNGEGKLDMVHIQNAALAGGVAVGTSGEMMLTPFGAMIAGTLAGMISVLGYKYLTPVLDSKLKIQDTCGVHNLHGMPGILGAIIGAIVALFATADIYGDGMGDVFPLISDGSRTAKQQSLYQFLALLVALGFAIIGGTVVGFILKLPIFGTPSDAECFEDAIYWEVPGGEGHQQLTVVINNEDPDTQA
What is the function of this protein?
Functions as a specific ammonium transporter.
What are the official names of this protein?
Ammonium transporter Rh type B-B, Rhesus blood group family type B glycoprotein B, Rh family type B glycoprotein B, Rh type B glycoprotein B.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: QUEA_PARPJ
Sequence: MLTLSDFDFDLPPELIAQVALPERSASRLLEVDNPAGAAGPARLIDRRFAELPECIAPGDLLVFNDTKVLKARFLGQKASGGKIEVLVERLTGERTALAQIRASKSPQPGTTIRLADAFDVTVGERVEPFYTLHFPDDCLTLIEQFGRLPLPPYIEHDPDSTDETRYQTVFAQNPGAVAAPTAGLHFDDALLARLDEKGVERATLTLHVGAGTFQPVRVENLAEHKMHSEWYHLPQALADKIAATRARGNRVIAVGTTSMRALEAAARDAEAAGRPLAAASTETDIFITPGYKFRVVDRLVTNFHLPKSTLLMLVSAFAGVETIRETYRHAIEQRYRFFSYGDAMLLTRRDA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO10_METVS
Sequence: MIFPIRCFSCGNVISEVYDEYKTRLSNVESPEEILNDLGVTKYCCRRMFASHRLENGKELFDDIVEYR
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_CHESB
Sequence: MKSAVIQLPGLNRDRDMIAALTKISGQAPVTVWQTETELPEVDLIVIPGGFSYGDYLRCGAIAARMPVMKAVAEKAAKGVLVIGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLQVANANTAFTRAYAPGQIIRCPVAHHDGNFFAAPETLARIEGEGQVAFRYAEGTNPNGSINDIAGIVNGAGNVLGLMPHPENLVEAAHGGTDGRALFESVLGRAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIB37_BPK3
Sequence: MATLKQIQFKRSKIAGTRPAASVLAEGELAINLKDSTIFTKDDSGNIIDLSISAGGNISGNVTIDGTLRVNGPINNFGNFSTSGQITAGSSISAQVFRALQGSFYSRASTGETANAHLWFENADGTERGVIYARPQTTTDGEIRLRVRQGTGSTTNSEFYFRSINGGEFQANRILASDSLVTKRIAVDTVIHDAKAFGQYDSHSLVNYVYPGTGETNGVNYLRKVRAKAAGTMWHEICTAQTGQADEMSWWTGNTPQSKQYGIRNDGRIAGRNSLALGTFTTNFPSSDYGNVGVMGDKYLVLGDTVTGLSYKKTGVFDLVGGGYSVASITPDSFRSTRKGIFGRSEDQGATWIMPGTNAALLSVQTQADTNNAGDGQTHIGYNAGGKMNHYFRGTGQMNINTQQGMEINPGILKLVTGSNNVQFYADGNISSIQPVKLDNELFLNSSNNTAGLKFGAPSKVDGTRAIQWNGGTREGQNKNYVIIKAWGNSFNATGDRSRETVFQVSDSQGYYFYAHRKAPTGDETIGRIEAQFAGELNAKSINAVENFKVNGLSTLVGGVTMSNGLNLTGGSSITGQVKIGGTYDALRIWNSRYGAIFRRSETSLHIIPTNENEGENGAINNLRPFSIELGTGTVSMLHDVHLGNSGSSTGLLQVSNSLKTIKMICPVTINERNAALTLDSPSSSSANYLQGSKAGTKSWYVGLGGAGNDLSLYSQSYGHGLVISDNFVSISKPLKVGNAQLGTDGNITGGSGNFANLNTTLNRKVNSGFITYGATSGWYKFATVTMPQSTSTAFFKIVGGSGFNSGLFTQCNIAEIVLRTGNERPADLNAVLYTRTIGAAFKNIAVNNVSGDTYDIYVYAGTYCNQLACEWACTENATISVIGINSSTQSPVDDLPDTAVNGQVANVLNNLVDSGKGKRYEAESEIAINSQTGIRIRSNADKTGSVATMLRNDGGSFYILFTDKNDTDGAATVNGEWNSKRPFAINLTTGEVMMNNGIAVRSAALFYNSINVKDNGSINFDKSGANPRNMRIFHAGDASRGNRIEIADETNYIAYFEKAPGGANRFVVNNATVSGVNQMNSFGVNTSNALGGNSITFGDTDTGIKQNGDGLLDIYANNAQVFRFQNGDLYSYKNINAPNVYIRSDIRLKSNFKPIENALDKVEKLNGVIYDKAEYIGGEAIETEAGIVAQTLQDVLPEAVRETEDSKGNKILTVSSQAQIALLVEAVKTLSARVKELESKLM
What is the function of this protein?
Structural component of the distal-half tail fiber.  It constitutes the part of the long tail fibers that recognizes the bacterial receptor.
What are the official names of this protein?
Long tail fiber protein p37, Protein Gp37, Receptor-recognizing protein.
What is the protein family that this protein belongs to?
Belongs to the tail fiber family.
What are the subcellular locations of this protein?
Virion.
Protein: FABH_SHIDS
Sequence: MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHIAAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDGAGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVTELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSVLVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP11_PEA
Sequence: MSLIPSFFSGRRSNVFDPFSLDVWDPLKDFPFSNSSPSASFPRENPAFVSTRVDWKETPEAHVFKADLPGLKKEEVKVEVEDDRVLQISGERSVEKEDKNDEWHRVERSSGKFLRRFRLPENAKMDKVKASMENGVLTVTVPKEEIKKAEVKSIEISG
What are the official names of this protein?
18.1 kDa class I heat shock protein, HSP 18.1.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_STAAC
Sequence: MKHQETTSQQYNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFGWIYSSSLASAAAVYTLNQFKAAPLIVTEDTLQKSKGKLQALVVNSANANSCTGQQGIDDARQTQTWVAQQLQIPSEHVAVASTGVIGEYLPMDKIKTGTEHIKDANFATPGAFNEAILTTDTCTKHIAVSLKIDGKTVTIGGSTKGSGMIHPNMATMLAFITTDASIESNTLHQLLKSSTDHTFNMITVDGDTSTNDMVLVMANHQVEHQILSQDHPQWETFVDAFNFVCTFLAKAIARDGEGATKLISVNVSGAKSISDARKIGKTIVSSNLVKSAIFGEDANFGRIITAIGYSGCEIDPNCTYVQLNQIPVVDKGMAVLFDEQAMSNTLTHENVTIDVQLGLGNAAATAYGCDLSYDYVRINASYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPDR1_RAT
Sequence: MLTRAPRRLVQGPRETWLLGGLWVWILCGLGMAGSPGTPQPCQAPQQWEGRQVLYQQSSGHNSRALVSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIEQATKLCAKIPLAEPWDPLDIPQNSTFEDQYSIGGPQEQIMVQEWSDRRTARSYETWIGVYTAKDCYPVQETFIRNYTVVLSTRFFDVQLGIKDPSVFTPPSTCQTAQPEKMKENCSL
What is the function of this protein?
Binds anionic lipids and gangliosides at acidic pH.
What are the official names of this protein?
Mammalian ependymin-related protein 1, MERP-1.
What is the protein family that this protein belongs to?
Belongs to the ependymin family.
What are the subcellular locations of this protein?
Lysosome lumen. Secreted. Note=Lysosomal and also secreted.
Protein: KDGL_HELPJ
Sequence: MSDFKVPPKAKGFKRLFKALFYSKDGLKCAWAEESAFRQIVILALFCIVLASYLTKDFLEWGLLILPCFLSVVIELINSSIEKAVDFTGTEFHPLAKKAKDMASSAQLIGLIFWAFIWGRYLLTLYFN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid.  Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
What are the official names of this protein?
Diacylglycerol kinase, DAGK, Diglyceride kinase, DGK.
What is the protein family that this protein belongs to?
Belongs to the bacterial diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IPDC_RHOJR
Sequence: MSTLRTALTELVGVQHPVVQTGMGWVAGPRLVAGTANAGGLGILASATMTYTELESAITKTKTLTDKPFGVNIRADASDAPHRIDLLIRESVRVASFALAPKQELIAKLKAAGVVVIPSIGAAKHAKKVASWGADAVIVQGGEGGGHTGPVATTLLLPSVLDAVDIPVVAAGGFYDGRGLAAALAYGAAGVAMGTRFLLTQESTVPDSVKHEYLARGLQDTTVSRKVDGMPHRVLNTDLVNSLEHSGNMRGLVAAARNASKFKAMTGMKWSTLVKDGLAMKKSSDRTWQQIIMAANTPMLLKAGLVEGNTHAGVLASGQVVGLLDDLPTCKDLIDGIVADAIKRIDALGALRA
What is the function of this protein?
Involved in the final steps of cholesterol and steroid degradation (PubMed:28377529).  Probably catalyzes the introduction of a double bound into the C ring of 5OH-HIC-CoA, leading to the formation of (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-3,5,6,7-tetrahydro-2H-indene-4-carboxyl-CoA (By similarity).
What are the official names of this protein?
(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxyl-CoA dehydrogenase, 5OH-HIC-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the nitronate monooxygenase family.
Protein: EFG_SHIF8
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRVGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_PROMP
Sequence: MEGINLNQIGVSFKGSGSYVPNQILTNQEISKKVETSDEWIKSRTGISQRRISGLSENVSEMGYKAALGAIEMARWDIETIDLIILATSTPNDLFGSAPEIQSKLGAINAVAFDLTAACSGFLFAAITATQFLKAGSYKRAVVIGSDQLSSYVDWNDRRSCILFGDGAGAIAIEGTNELDNLLGFSMRTDGQRGSFLNLPSQNNQDLIINDINFSSGGFSSIKMNGQEVYKFAVREVPLIIDNLFKKTNFNSEKINWLLLHQANQRILDSVGERLNVSTEKILSNLSNYGNTSAATIPLMLDEAIRNKKIKENDIIATSGFGAGLSWGAALIRWG
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUBP1_CAEEL
Sequence: MSDVPDDANAGCPGTGSAGAGKASGCAGCPNQGSCATGQGPPPDADVPKIQDRFSRIKHKILILSGKGGVGKSTLTSNLARALASDPSKQVAILDVDICGPSQPRMMGVEDEEVHNSADGWTPVGIQPNLTLMSIAFLLGDKNDAVIWRGARKNGMIKQFLKDVDWGEVDYLLIDTPPGTSDEHISLVQFLLQAGPLDGALIVSTPQEVSLLDVRKEVSFCVKTKVPILGVVENMARFVCPNCAHTTLLFPTSTGGAEQMCKDSNLELLAQLPLEPALAKALDNGEDFFETNPDSTLAKSFLDLAEKVKAKLV
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (By similarity).  Regulates cilium formation and structure (PubMed:23807208).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP1 homolog, Nucleotide binding protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection.
Protein: KWAB_ECORM
Sequence: MTTQQLKEKISKIIDNFSGIRVVFTTTANELKLSRIEGSALNSIAEGFIDKIKEDIINNEDLTSPLLSNFDDRKNALFKFDYEQYPEEFNKITQAIAIPPNSQDYYNPLNKFTDVKGIIILISGDNKCLALYKNKTNLAVLRNSRKMFNLVPDPDGYLKQLPNEILRLDFNYDLFSIGEDFYIKNHKTLETQMKFHQVIEAQAVIALNSLRDSLLIEDISGLEKSSREISFARKLAKISKHSPVLGKIDTKTIIDYVSQHKYLSAILQINEAGDKLLIKTKTSQKHFIKLMSDDYLQSDLTKIIYMSIAKDRLDE
What is the function of this protein?
Component of antiviral defense system Kiwa, composed of KwaA and KwaB.  Expression of Kiwa in E. coli (strain MG1655) confers resistance to phages lambda and SECphi18.
What are the official names of this protein?
Kiwa protein KwaB.
Protein: YCIB_SHESR
Sequence: MKQLLDFLPLIIFFAVYKFFDIYIASGALIAATALQLVVTYALYKKLEKMHLITFAMVTVFGTLTLVFHDDAFIKWKVTIIYALFALALGVSQLLNKSILKSMLGKEMKVADNIWAHVTWYWVSFFAICGLVNIYVAFRLPLETWVNFKVFGLTALTLINTVITVFYLYKHLPEDQRKELK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.