PharMolix/UniProtQA huggingface dataset:
Protein: NU2M_SYCAU
Sequence: MNPLILSMIMATIILGTLIVMTSSHWLMVWIGFEMNMLAILPVLMKKYNPRSMEAATKYFLTQATASMLLMLAITINLIYSGQWSTANPLNPTTSIIMTLALAMKLGLSPFHFWVPEVTQGIQLSSGLILLTWQKLAPMSILYQISPAINMDLLLSMSLMSVAIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVMTYNPTMALLNLIIYILLTTTTFMTFMLNSTTTTLSLSHTWNKTPLLTTTILILMLSLGGLPPLSGFLPKWMIIQELTKNDSIITPTIMAITALLNLYFYMRLTYSTSLTMFPSVNNMKMKWQFNSMKQTTHLPPLIVLSTLILPMSPMLMLLE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COAX_PHEZH
Sequence: MLLAIEQGNTNTLFAVHDGERWIAQWRAATDSTRTADEYAVWLSQLLSMAGLALGAFDGCIISSVVPQSIFNLRNLSRRYLHVEPLVIGENAELGIPIRIDKPSEAGADRLVNAIGAHIAYPGPLIVIDSGTATTFDVIAADGGFEGGVIAPGINLSMEALHTAAAKLPRVAIQKPQKVVGTDTVGAMQAGVFWGYIALIEGLIARIKAERDEPLTVVATGGVASLFHGATAAIDKFDPDLTIRGMLEIWRRNQAKA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI142_ARATH
Sequence: MVAAIIAGAAVAAAAYAGKYGIEAWQAFKLRPVRPRMRKFYEGGFQATMNRREAALILGVRESVAAEKVKEAHRRVMVANHPDAGGSHYLASKINEAKDMMLGKTKNSGSAF
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM14-2, Chaperone DnaJ-domain containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TIM14 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Single-pass membrane protein.
Protein: IF2_BORGP
Sequence: MSENIDDIKNEDSKKIKIIKLRKKVVKIVTHNDLNGKNNSNSSINLDKHNNKVEYSQNRDNRAGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDNRTGGYSQNRDSFPSQYQVSTKKTYVGKNTSQNKYTTTPMSFRRVIKAKVPSIVSSASSVDSENIKELNRKLGEKKKQQQESQKSYKRKKAETESKTIEQKVFEQLQKKKRENLANPIPKSIDIMGSITVSDLARKMNLKSSDLIAKLMALGVMVTINEKIDSDTATILVEEYGSKVNVVSIYDETFIEEEVEDQSKRIEKPPVITIMGHVDHGKTKLLSVLQNIDINQTESGGITQHIGAYTIVYNGREITFLDTPGHEAFTMMRSRGAQVTDIVVLVVSAIDGVMPQTIEAINHAKEANVPIIVAINKIDLPDSNPDKVKHQLSEYDLVPEDWGGDTIFVLISALKNIGISELLDMILLQSDMMLLKANPSKRAIGKVLDAKIDLGRGIVCSVIIEDGTLYIGDSFVGGVCYGKVKALISDKGVSVKSVGPAKAISVLGFSSMPQAGDPFQVTKTEKEAKLISSKRQDLKKYESSKNVKKVTMLNLYDSIKEGALKELKIILKADVQGSVEALKNSLEKLTNDEVRVRVVHSSAGVITETDISFASASDAIVIGFHVRPTSKAQILADQEKVEIRKYNVIYDAISDVKSVLEGMLEPDVEQQFIGFAEVRAVINVPKVGVIAGCYVSRGIIKRDAITNVMRDGLQIHSGKISSLKRFKDDVKEVAEQYECGIMIDNYANIKEGDIIEAFEVKKIKKTFKT
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_RIPO1
Sequence: MKILILNAGSSSQKSCLYDFKEKNFLDNPVEPIWKADIDWTLATGQGILTVKANGIKQKITLNSDDHHHGIAKMLGTLVEGKTKVIQHLSDISIVGHRVVHGGTDYSEATLITPDVKATIARLIPLAPTHNPSHLEGIEAIEQVLGNIPQVAVFDTAFHSQMPLEASVYPIPYEWLDKGIRRYGFHGTSHKYCAEKASQLLNKPLTHLKLITCHLGNGCSLAAIKNGISIDTTMGFTPLEGLMMGTRSGSIDPAILIYLMREYDFTFEQLNEMLNQESGLKGVSGISADLRAIFEAINQGNDRAQLALDMYLHRLRSQIGSMLASLGGLDALIFTAGIGENAAIVREKACQGFSFLGLKLDLEKNANSPVNIDISTPDSTVRILVIHTQEDWAIAQECCHWLNK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_NEIMA
Sequence: MNINATLFAQIIVFFGLVWFTMKFVWPPIAKALDERAAKVAEGLAAAERGKSDFEQAEKKVAELLAEGRNQVSEMVANAEKRAAKIVEEAKEQASSEAARIAAQAKADVEQELFRARESLREQVAVLAVKGAESILRSEVDASKHAKLLDTLKQEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CF20D_HUMAN
Sequence: MIKRKIWCNLCIDLVAFTSEIFKGAVFQSLDGIVVSANCKLRKIFTLKSKPQDTADKDAVYGVPFSTDEPTDIIPRSCQLMTDVPHVTQLLNMTKLRQTEIKFGGHPLRSAESDQFINRGTSITRNSKNQDVCHIAFGSKVLGPPPLSGRRNNMKISSETVRSVGSKNNRSCQPSTVEKCVNGTEMSALLIPESEEQGNKENIHQIKQTVPIHAANLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGSSSGNNRIEDKASTILTTVSQQGAELLNSGTLGPQSPDQSDEWIFPENADHISYLASSRQSLLLGDDSCNPSHLWLEASKESEHDQQAEESQSVPKDIFTFSSRPRSAPHGKTQTMSPEELSFILDLKEDNSVTSRDTQSEDDFYGGDSSEEGNHSIQGSRGPTTGPSELTQLTLESLLGKAAKRTSKEYLRSAYTEAGATESQDSSMEQIDRNNFEMSLLPTTCLSPTGRRCGSCQKTPEPVIKAKDLSAQQVPASLNKTSLKEISGERLSSIPEASEYDWRNYQPSQMSESELQMLASLRWQQNEELEDAGTSHGLSASQVDNCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRDWLNMLSPPIVPPSQQPAEQRPDSCESLSVQGEEDLSVEEDEEVLTLLYDPCLNCYFDPQTGKYYELV
What are the official names of this protein?
Protein CFAP20DC, Uncharacterized protein C3orf67.
Protein: RMS5_EMEND
Sequence: MLNIIKSKIKNTYKKKALNDENVSFYNKNFVPAVRDWKNSIYVYNKNTLSLIPVASRLVMKLIKGYFNSYNLNIESKLRNKRLRRRYRKLSTNKIFISEGEFKHTNDKINITLYVYNKQKLNYLAKLKKKYTSLFGKDIFIKKLQLIKSKAIGILTQQQKKSKTLTNVLPKYSTKVNKIQNIYYRTYIKKSIKRLKYYMYYKQLLYINKAKFENSYLQGLIDLIKKIYKKNIEFNIINLKYLYFNSDIYTQPLVLKLRKKRDLLRYLKDLVNKAKIEKVSLNKRSEYYFNLENLFTRNNVDITNNLLNNLMQYNKKNSEYLKKVILNDIKYKRVSGVRLEAAGRLTKRYTASRSQYKFKYKGNLVNTYSSIQGYPSSLIRGNDKPNLQYTKLNSKSRIGSFGVKGWVSGV
What is the function of this protein?
Essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits.
What are the official names of this protein?
Ribosomal protein S5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL14_RHIE6
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRKYASIGDVIVVSIKEAIPRGRVKKGDVMKAVVVRTAKDIRRPDGSVIRFDTNAAVLIDNKKEPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PURA_LYSSC
Sequence: MTSVVVVGTQWGDEGKGKITDFLSQKADAIARFAGGDNAGHTIKIDGETYKLHLIPSGIFYKEKTSVIGNGLVVNPKSLVTELKGLQERGINTDNLRISNRAHVILPYHIKQDIADEESRGDNKIGTTCKGIGPCYQDKVARIGIRMADLLDKDIFEEKLRHNLAIKNKLFEKFYEVEGLTFEEIFEEYYGYGQEIAKYVTDTSKILNDVLDEGGKVLFEGAQGILLDVDQGTYPYVTSSNPVAGGVAIGAGVGPSRVTSVIGVSKAYTSRVGDGPFPTELFDEVGQQIREVGREYGTTTGRPRRVGWFDTVVVRHSRRVSGITHLALNSIDVLSGLETVKICTAYNYKGETITEYPANLHIIEQCEPIYEELPGWSEDVTACRTLEELPENARRYVERVSELTGIQIATFSVGPAREQTNVLVDVWEA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_THEGJ
Sequence: MLDIKLIREKPELVKKDLIKRGETEKVKWIDEILELDRKWRENLKKINQLRKERNQLAVQIGKRKKAGEPIEDLLARSNEIVKQIEELEKEVEALKKKIDYYLWRLPNITHESVPVGKDDTENVPIRFWGKAKVWEGFLESFKEQSLGKMDYEVLSWRPRLHVDMLELLRGADLERAAKVSGSRFYYLLNELVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGATTFEDFEDVIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHEKIIANAEELFQELEIPYRVVNICTGDLGYVAAKKYDIEAWMAGQGKFREVVSASNCTDWQARRLNIRFRDKTHEKPKFVHTLNSTAIATSRAIVAILENHQTEEGVVKLPKALWKYTGFKEILPASMKEKCCQD
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETI_PSESM
Sequence: MPKVGMQPIRRQQLIQATLTAVDQVGMGDASIALIARLAGVSNGIISHYFQDKNGLIAATMRHLMNALIQNVRERRQALTEDSPRAHLQVIIEGNFDASQVSGPAMKTWLAFWATSMHHPSLHRLQRINDHRLYSNLCCQFRRTLPLEQARNAARGLAALIDGLWLRGALSGDAFDTEQAQRIAYEYMDFQLAKSAS
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: SSB_SHEHA
Sequence: MASRGVNKVILVGNLGKDPEVRYMPNGNAVANFTVATSESWKDQQGQPQERTEWHNIVMYRRLAEIAGEYLKKGSKIYIEGKLQTSKWQDQATGQDRYKTEINASEMQMLDSRGQGGGQQGGGDYGQQQNQYNAPQQQAPQQGYAPKPQSAPQQPAYAPKPQSAPQQPAQQQGGYQSQGQQPQAPAYAPKPQAAPQQRPAPAPQQAAPQQNFTPDLDDGWDDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: U603_ORYSJ
Sequence: METLLSPSTLLSPLRGSKKKPASPAASASSSSSSPARSVVSCALRRQQPPPQAVAAWRGDGGRGGGVGSWATFLQHGLAAAALSLAISMAPAPAPAVASEFDVLNGGPPEDTYVVDDAGVLSRVTKSDVKRLVRDLESRKNIRINFITVRKLTSKADAFEYADQVLEKWYPTVEEGNNKGIVVLVTSQKEGAITGGPAFVQAVGDEILDSTVSENLPVLATDEKYNEAIYTTAKRLAAAIDGLPDPGGPTFKDNKRESNFKTKEETEEKRGQFTLVVGGLLVIAFVVPMAQYYAYISKK
What are the official names of this protein?
UPF0603 protein Os05g0401100, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the UPF0603 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein; Lumenal side.
Protein: R1AB_CVMJD
Sequence: MAKMGKYGLGFKWAPEFPWMLPNASEKLGNPERSEEDGFCPSAAQEPKVKGKTLVNHVRVDCSRLPALECCVQSAIIRDIFVDEDPQKVEASTMMALQFGSAVLVKPSKRLSVQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCLGNGRFIGWFVPVTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHSRRAVTMPVYDFNATDVVYADENQDDDADDPVVLVADTQEEDGVAKEQVDSADSEICVAHTVGQEMTEPDAVGSQTPIASAEETEVGEACDREGIAEVKATVCADALDACPDQVEAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFKVCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKLVKSAPKSIILPQGGYVADFAYFFLSQCSFKVHANWRCLKCGMELKLQGLDAVFFYGDVVSHMCKCSFKAYF
What is the function of this protein?
Non-structural protein 1: binds to the 40S ribosomal subunit and inhibits host translation.  The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation.  By suppressing host gene expression, nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response (By similarity).
What are the official names of this protein?
Replicase polyprotein 1ab, pp1ab, ORF1ab polyprotein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses polyprotein 1ab family.
Protein: MURG_YERPY
Sequence: MSGKTKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEASLVPQHGIEIDFIKISGLRGKGLMAQLTAPIRIYRAVRQAQKIMRDYQPDVVLGMGGYVSGPGGLAAWLCGVPVVLHEQNGIAGLTNRWLARIAKKVLQAFPGAFPNADVVGNPVRTDVLALPLPAVRLSGREGPIRVLVIGGSQGARILNQTLPLVAASLGEQITLWHQVGKGALPEVSQAYQQAGQAGHQVVEFIDDMAAAYAWADVVVCRSGALTVSEVAAAGLPAIFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQFTATSVSSLLAGWDRATLLSMAERARSVAIPDATERVAAEVVAASKSA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNAA_THEPX
Sequence: MYGDHRQIWERIVEVIKSELTPTSYNTWLVHIKPLAIIDDVLFLSTPNTFTKNIINGRYINIIYDAASKATNKLYEIKILSEDEEEYREIKESIEKENLTESTTLSTLNPKYTFDTFVVGNSNKLAHAACLAVAQAPAKAYNPLFIYGGVGLGKTHLMHAIGHFINKHQSGYKIMYVTSETFTNELVNSIKDDKNEEFRNKYRNIDVLLIDDIQFIAKKERTQEEFFHTFNTLYEANKQIVISSDRPPKEIPTLEERLRSRFEWGLIADIQPPDYETRIAILKKKAQTENLNIPDEVLAYVAEKIQSNIRELEGALIRIVAFSNLTKANIDLELAKHALKEIVSNKTREITVKLIQEEVCKYYNIKLEDFRSRKRTKNIAYPRQIAMYLARELTDLSLPKIGEEFGKDHTTVIHAYEKISNEIKQDELLSRQIEELKKRIKGY
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACA_STRPN
Sequence: MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTLAVAAEVNKEEQNLGIVIDAYGAGPFIVATKIKGMVAAEVSDERSAYMTRGHNNSRMITMGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: Y1319_MYCTO
Sequence: MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTALYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIADRLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASPHRRPPGSIHLTAEHAEEIRTDRLG
What are the official names of this protein?
Uncharacterized protein MT1361.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RDGC_XYLFA
Sequence: MFFRNLTLFRFPTSLDFSQIDSILPNARLRPVGPLEMTSRGFISPFGREEQEVLNQRQGDFLWLTVGSEDKILPASVVNDLLTRKCSEIEEKKGHPPGGRERKRIKDDLIHELLPRAFVKKSRIDAMLDLRYGYVAVDTASRKAAETVISEIRDLLGSFPALPLNAEISIRSMLTSWIAGEPLPEHLNLGDECEMKDATEGGAIIKCQHQALRCEEIDKHLEVGKQVSKLALILDDHVSFVLGDDLVIRKLKFLDGMLDQLEHSDTDGIRAELDARFALMSAEIRRLFLLLEVPLKLSKANN
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL17_PHOV8
Sequence: MRHNKKFNHLGRTASHRSAMLSNMACSLIKHKRITTTVAKAKALKKFVEPLITKSKDDTTNSRRVVFSNLQDKFAVTELFKEISVKVADRPGGYTRIIKTGHRLGDNAEMCFIELVDYDENMAKTATAKKATRTRRSKKSAAATEAPAAPAAETTEEAPKAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: CMOA_ECO7I
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRHHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHQAGFEHSELWFQCFNFGSLVALKAEDAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: GCSPA_NITMU
Sequence: MPFIPHTEEDIQAMLASIGANSIDELFDEIPPALKTGSLKRVPPGLSEMEISRLMLERAEQDGRYLNFIGAGAYEHHIPAAVWQIATRGEFYSSYTPYQAEASQGTLQLLYEYQTMMASLTGMDVSNASMYDGASALAEAALMAVRSHRTSRRILIPQTVHPVYRSVVRAIVKNQGIEVVEVPYDKLSGQTSLDGLKNFGSEEFAALVIPQPNFFGVLEDVDTLTDWAQSRDAFAIAVVNPMALAMLTPPGEWGEKGADIAVGEGQPLGIPLSSGGPYFGFMACKQPLVRQMPGRIIGRTTDQEGSDGFVLTLQAREQHIRRSKATSNICTNQGLMVTAATIYLALLGPEGLRRTAAQSHANTAALLEKLEKLKGVKRVFSGPVFHEAVISLPRPSASVLQALEARRILGGLNLKEYYPELGDAVLVCATETKTSGDMENYVTQLGEVIRNS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: RLMH_CERS5
Sequence: MKLQLCAVGRLRSGPERDLVEDYLGRFERTGRPLGLPAVQLLEVEDRKGGGMEAEADLLARAMAPGAVLAILDERGRTLSSPEFAEQLARWRDAGRDVALAIGGADGLAPRLRDRADLALSFGRMVWPHMLVRVMLAEQLYRAATILAGSPYHRV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOU1_SCHPO
Sequence: MTSMFSLKGKTTLITGGSGGIGFSIAKAFAAAGSNVGLLYGRNKKALEYAAELRDKHGVQAKAYSCPIENRSAVIETTNQAVEELGGRLDVMIANAGIAIPHLSLEDKNEDIWTKVVGINLNGAYYTAQAAGHHFKKQGKGSLIFTASMSGHIANWPQQWASYHATKAAVKHLARALAVEWAPFARVNSVSPGYIDTDLTLYADENLRKKWKEYTPQARIGLPDELPGAYLYLASDASSYCTGSDIIVDGGYCSR
What is the function of this protein?
Catalyzes the NADP dependent reduction of L-sorbose to D-glucitol.
What are the official names of this protein?
Sorbose reductase sou1, Sorbitol utilization protein sou1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: REV_HV2CA
Sequence: MTERADEEGLQRKLRLIRLLHQTNPYPQGPGTASQRRNRRRRWRQRWRQILALADRIYTFPDPPADPPLDRTIQHLQELTIQDLPDPPTHPPESQRLAEA
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rev, Regulator of expression of viral proteins.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: MDH_VIBCH
Sequence: MKVAVIGAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTPVTIKGYAGEDPTPALEGADVVLVSAGVARKPGMDRADLFNVNAGIVKALAEKIAVVCPKACVGIITNPVNTTVPIAAEVLKKAGVYDKRKLFGVTTLDVIRSETFVAALKDKDPGQVRVPVIGGHSGVTILPLLSQVEGVSFTDEEVAALTKRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLALVKALQGESDVVEYAYVEGEGEYAPFFAQPIKLGKNGVEALLDIGKLSAYEQAALDGMLDTLKGDIQIGVEFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: AK1A1_PIG
Sequence: MAASCVLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIYGNELEIGEALQETVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTIRYDATHYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEKYNRSPAQILLRWQVQRKVICIPKSVTPSRILQNIQVFDFTFSPEEMKQLDALNKNLRFIVPMLTVDGKRVPRDAGHPLYPFNDPY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols.  Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids, with a preference for negatively charged substrates, such as glucuronate and succinic semialdehyde (By similarity).  Plays an important role in ascorbic acid biosynthesis by catalyzing the reduction of D-glucuronic acid and D-glucurono-gamma-lactone (By similarity).  Functions as a detoxifiying enzyme by reducing a range of toxic aldehydes.  Reduces methylglyoxal and 3-deoxyglucosone, which are present at elevated levels under hyperglycemic conditions and are cytotoxic.  Involved also in the detoxification of lipid-derived aldehydes like acrolein (By similarity).  Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs (By similarity).  Displays no reductase activity towards retinoids (PubMed:12732097).
What are the official names of this protein?
Aldo-keto reductase family 1 member A1, Alcohol dehydrogenase [NADP(+)], Aldehyde reductase, Glucuronate reductase, Glucuronolactone reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Apical cell membrane.