PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_THEON
Sequence: MAKFIFVTGGVVSGLGKGITSASLGMLMKARGFKTTNIKIDPYLNYDAGTMNPYQHGEVFVLDDGGEVDLDLGNYERFLDTSLTFDHNITTGKIYSAVIEKERRGDYLGATVQVIPHITNEIKERIREIARDYDVVVVEIGGTVGDIESMPFLEAARQMQLEEGRDNVAFVHVTYVPKLRVVGEQKTKPTQHSVKELRSLGIQPDAIVARSEDPLEESARRKISLFTNVPPEAVISAYDVEDTYEVPLMLEKEGLARYITKRLGLPEREPELDAWREMVERYKSLTDTVEIAIVGKYVKLSDSYLSIKEALKHSGVANGVKVKIRWVEAEDVEKHGVKLLEGVDGIIVPGGFGARGTEGKMMAIRYARENDIPFLGICFGFQLTVVEFARNVLGLKGAHSTEIDPQTPYPVVDLMPEQRGLDKLGGTMRLGAYPVKIKPNTLARELYGRELIYERHRHRWEVNPEFIERFEKAGLVFSGVAGDDERRMEILELPEKRYFIATQFHPEFKSRPMNPAPVFRGLVKAAKEKKFGD
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CBK1_CANGA
Sequence: MFGGEYDHAYDANNGQRFQPPVLDAMEFEKPGSPSVGDHFLRQQISNQSLHDQYSSHMEQQQQQQQQQHNAAYGAGFTDIPQLHPSTPPHGLVQKISNGNFHPAMNQGGNIPSTSNMNNMFNTPPPTMGNNPLYSHDNNSTNLLQDNLNQARSQFSPDRYSVDSDFNNGAGNHVMANGNYNINGSQSSSPYHQPQTFYTNSNLSSGQLSAHRSSPQRQPAQPLQQTTFTQLPQPSLPPQQQQQQQQQQQQQQQQQPKFQSMVPPQQTQLQQQQQQELQNAGSYMYFERRPDLLSKSTQDKAAAVKLKVENYYQQSVKYAIERNERRVELETELGSHNWSEERNARQLASLGKKESQFLRLRRTRLSLEDFHTVQVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGTDSPWIVSLYYSFQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILIDIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATTKNGAPNDAGDGSNNRQTMIVDSINLTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQDCDWWSLGAIMYECLIGWPPFCSETPQETYRKIMNFEQTLQFPEDVHISYEAEDLIRRLLTHSNQRLGRQGGADEIKSHPFFRGVDWNTIRQVEAPYIPKLSSITDTRFFPTDELENVPDSPAMAQAAKQREQMMKNGVNPNQNQVKEDLPFIGYTYSRFDYLTRKNAL
What is the function of this protein?
Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.
What are the official names of this protein?
Serine/threonine-protein kinase CBK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.
Protein: NU5C_BARVE
Sequence: MEHTYQYSWIIPFIPLPVPILLGVGLLLFPTATKNLRRMWTFLSIFLLSIVMIFALYLSIQQIILSCIHQNVWSWTINNEFSFEFGYFIDPLTSIMSILITTVGILVLIYSDNYMSHDQGYLRFFAYMGFFNTSMLGLVTSSNLIQVYFFWELVGMCSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGLYWITGSFEFQDLFEIFNNLILNNRVNFLFLTLCAFLLFVGPIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFIVIPSIMYIISLIGIITVLLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSIIHSMEAIVGYSPDKSQNMILMGGLTKHVPITKTAFLVGTLSLCGIPPLACFWSKDEILNDSLLFSPIFAIIACSTAGLTAFYMFRIYLLTFEGHLNTYFINYSGKKSSSFYSISLWGKEEEKKLNRNFGLVPLLTMNNTKRASFFYKKTYKISNNVRNQTFITVENFGLNTRTFYYPQESDNTILFPMLVLLLFTLFIGAIGIPFNQEGIDFDILSKLFTPSINLLHKNSQSFVDWYEFLRNATFSVSIAFFGIFIAYCLYKPFYSSLLNLTLLNSFQKWNSKRIRWEKLINFVYNWSYNRGYIDAFFKTSLIESIRRLAKLTNFFDKRIIDGITNGVGITSFFVGEVTKYIGGSRVSSYLFLYLSYVLIFLTILFFFYFEKF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: BCHN_RHOPB
Sequence: MTVLAQGCDVAPPNNLTKPVRHESGQREVFCGLTGIVWLHRKIQDAFFLVVGSRTCAHLIQSAAGVMIFAEPRFATAIMEEKDLAGLTDANTELDRIVTQLLTRRPDIKLLFLVGSCPSEVIKLDLSRAALRLSQTFSPGVRILSYSGSGIETTFTQGEDACLASLVPELPAASGKDASLLVVGSMADVVEDQFVRMFEALGIGPVQFLPPRNSATLPSVGPNTKFLLAQPFLADTARELENRGATRLRAPFPLGVEGTTAWLRAAANAFAIDPALFDKVTQPARARAERALDNYRKELAGRRIFLFPDSQLEIPLARFLSRELGMQLVEVGTPYLHREHLAEELKLLPPDVQITEGQDVDLQLDRCRLARPDLVVCGLGLANPLEAEGMTTKWAIELVFTPIQGYEQASDLAELFARPLVRRAKLVA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
Protein: RL10_CORGB
Sequence: MANPRNEAALAELKARFAETDTVVLTEYRGLTVAQTTELRKALGFDVQYSVAKNTLVKIAANEAGIEGLDDLLTGPTAVAFIKGEAVDTAKVLKKFGEENKAFVVKGGYMDGNALTAEQVNAIAELDNRETTLAKLAGAMKGSLAKAAGLFNAPASQVARLAVALQDKKDA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: FGF4A_XENLA
Sequence: MTVPSALVPILLLGTAAVMVQCLPLSFQRNDTVERRWETLFSRSMGEKKDTSRDSDYLLGIKRQRRLYCNVGIGFHIQVLPDGRINGMHSENRYSLLELSPVEVGVVSLYGVKSGMFVAMNAKGKLYGSRYFNEECKFKETLLPNNYNAYESRKYPGMYIALGKNGRTKKGNRVSPTMTLTHFLPRI
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.  Good candidate for an inducing factor with possible roles both in mesoderm induction at the blastula stage and in the formation of the anteroposterior axis at the gastrula stage.
What are the official names of this protein?
Fibroblast growth factor 4A, FGF-4A, Embryonic fibroblast growth factor I, xEFGF-I, Heparin-binding growth factor 4-I, HBGF-4-I.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: TGT_HELPG
Sequence: MDFQLQAIDKHARAGLLNLAHSQVATPVFMPVGTQGCIKSLDAMDMQEILGAKLILANTYHMYLRPGEKVVEQLGGLHRFAQFHGSFLTDSGGFQAFSLSGNVKLQEDGIVFKSHIDGSKHFFTPAKVLDIQYSLNSDIMMVLDDLVGLPAPLKRLEESIKRSAKWANLSLEYHKEKNRPNNNLFAIIQGGTHLKMRSLSVELTHKGFDGYAIGGLAVGESVDEMLETIAHTAPLLPKDKPRYLMGVGTPENILDAISLGVDMFDCVMPTRNARNATLFTHSGKISIKNAPYKLDNTPIEENCACYACKRYSKAYLHHLFRAKELTYARLASLHNLHFYLEMVKNARNAILEKRFLSFKKEFLEKYHSCSH
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TGON2_HUMAN
Sequence: MRFVVALVLLNVAAAGAVPLLATESVKQEEAGVRPSAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKSGAEAKTQKDSSNKSGAEAKTQKGSTSKSGSEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSPNRSGAEAKTQKDSPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSGAEDQTPKDVPNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKSGAEEQTSKDSPNKVVPEQPSRKDHSKPISNPSDNKELPKADTNQLADKGKLSPHAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEKEKMSGSASSENREGTLSDSTGSEKDDLYPNGSGNGSAESSHFFAYLVTAAILVAVLYIAHHNKRKIIAFVLEGKRSKVTRRPKASDYQRLDQKS
What is the function of this protein?
May be involved in regulating membrane traffic to and from trans-Golgi network.
What are the official names of this protein?
Trans-Golgi network integral membrane protein 2, Trans-Golgi network glycoprotein 46, TGN38 homolog, hTGN46, Trans-Golgi network glycoprotein 48, hTGN48, Trans-Golgi network glycoprotein 51, hTGN51, Trans-Golgi network protein 2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Note=Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes.
Protein: RH35_ARATH
Sequence: MESIMEEADSYIEYVSVAERRAIAAQKILQRKGKASELEEEADKEKLAEAKPSLLVQATQLKRDVPEVSATEQIILQEKEMMEHLSDKKTLMSVRELAKGITYTEPLLTGWKPPLHIRKMSSKQRDLIRKQWHIIVNGDDIPPPIKNFKDMKFPRPVLDTLKEKGIVQPTPIQVQGLPVILAGRDMIGIAFTGSGKTLVFVLPMIMIALQEEMMMPIAAGEGPIGLIVCPSRELARQTYEVVEQFVAPLVEAGYPPLRSLLCIGGIDMRSQLEVVKRGVHIVVATPGRLKDMLAKKKMSLDACRYLTLDEADRLVDLGFEDDIREVFDHFKSQRQTLLFSATMPTKIQIFARSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTSPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDREYAISSFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPAEIENYVHRIGRTGRCGKTGIATTFINKNQSETTLLDLKHLLQEAKQRIPPVLAELNDPMEEAETIANASGVKGCAYCGGLGHRIRDCPKLEHQKSVAISNSRKDYFGSGGYRGEI
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 35.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX41 subfamily.
Protein: BPHC2_RHOGO
Sequence: MTATPKFAHVVLQTSRFEAMRDWYCTVLDAHVVYEGHGLCFITFDEEHHRVALLGAPTALEPRNPGAAGMHHTAYTFDTLGDLLDRYESLKSKGIEPKVPIQHGVTTSLYYQDPDGNFVELQIDNFSTPDEATAYMNGPEYGGNPVGVSFDPVLIPQALSAGTPVDRITTHAWALETTPDLPNPMIALTS
What are the official names of this protein?
Biphenyl-2,3-diol 1,2-dioxygenase 2, 2,3-dihydroxybiphenyl dioxygenase II, DHBD II, 23OHBP oxygenase II, Biphenyl-2,3-diol 1,2-dioxygenase II.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: IFNL2_MOUSE
Sequence: MLLLLLPLLLAAVLTRTQADPVPRATRLPVEAKDCHIAQFKSLSPKELQAFKKAKDAIEKRLLEKDLRCSSHLFPRAWDLKQLQVQERPKALQAEVALTLKVWENMTDSALATILGQPLHTLSHIHSQLQTCTQLQATAEPRSPSRRLSRWLHRLQEAQSKETPGCLEASVTSNLFRLLTRDLKCVANGDQCV
What is the function of this protein?
Cytokine with antiviral, antitumour and immunomodulatory activities.  Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues.  Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state.  Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1.  Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense.  Plays a significant role in the antiviral immune defense in the intestinal epithelium.  Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
What are the official names of this protein?
Interferon lambda-2, IFN-lambda-2, Interleukin-28A, IL-28A.
What is the protein family that this protein belongs to?
Belongs to the lambda interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPH_PASMU
Sequence: MTQFKLIGFDLDGTLVNSLPDLALSVNSAFAEFDLPQAPEDLVLTWIGNGADILIARALAWAKAQTGKTLNDEQIKALKRRFGFYYGENLCNLSVLYPNVKSTLETLKQKGYLLAVVTNKPTKHVQPVLQAFGIDHLFSELLGGQSLPAIKPHPAPLYYLCGKFGLYPKQVLFVGDSKNDILAAHTAGCAVVGLTYGYNYNIPIAESKPDWVFDDFAQILTILE
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: PDXA_HELPS
Sequence: MAKKKIAISCGDIQGVGLELILKSHKEVSALCEPLYLIDSELLERANQLLNNAYETKTLNTLAINAPLPLLNSGTIGKVSAQSGAYSFESFKKACELADDKEVDGICTLPINKLAWQQAQIPFVGHTDFLKQRYKDHQIIMMLGCFRLFVGLFSDHVPLGAVSQLIQVKALVRFLLAFQKSTQAKIIQVCGFNPHAGEEGLFGKEDAKILKAIQKSNQTLGFECFLGPLPADSAFAPNKRKITPFYVSMSHDVGLAPLKALYFDESINVSLNAPILRASTDHGTAFDIAYQNKANNKSYVNAIKYLA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_STRCO
Sequence: MTTVAGGVRASARVLARGDGRGGTVLPVLEGEGPLAVRRTRGSGAEARVMLVGAMSGPLGGDHFEVGAHAANGARLRVGSAAATLALPGQDKAGARYDVRLTVDDDAELYWLPEQLISAGGSDLTVTTSVDLAAGARLLLREEQVLGRAGEEPGRLTSRLTLRIDGRGVLDQELLCGPGAPGGWDGPAGLAGHRAVGQLVVVRPGFATEPPAARVFEEGAAVMPLAGPAALVTAVAPDALRLRRLLDGALASLD
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_BOVIN
Sequence: MPAAGSEPSRPPSPPGVQEQSAEPRPPPPPHGELQYLGQIEHILRCGFRRDDRTGTGTLSVFGMQARYNLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDGLGFSDRAEGDLGPVYGFQWRHFGAEYKDMDSEYSGQGVDQLQKVIDTIKTNPNDRRIILCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITDLKPGDFVHTLGDAHIYLNHIEPLKTQALMELRGQSSRSLDGDGQAGTSRWAPVATDTERDRCCELQREPRPFPKLKILRKVETIDDFQAEDFQIEGYNPNPTIKMEMAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Protein: MGSA_PASMU
Sequence: MQSTARTLSVNKHIALVAHDHCKQDLINWCKTHRTLLAQHTLYATGTTGNLIQKEANLPIKSLLSGPMGGDQQLGGLIAEKQIDVLIFFWDPMNAVPHDPDVKALMRIATVWNIPVAMNMATADFLITSPSFAQETQVRIPDYDGYLKERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: MURB_CLOD6
Sequence: MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPRTEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTAQSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDMEGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQPLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDILDLIYVIKSAVYAKFGVMLEEEVKILGED
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP0A_CLOPA
Sequence: MEYSKISVLIADDNKEFCNILNDYLLNQSDIVVVGIAKDGIEALKLIEEKKPDLVILDIIMPNMDGLVVLEKLANINIDPVPNVIVLSAVGQDKITQRAITLGADYYVVKPFDMDVFTKRIRQMFNNTILDSETKKTMPISEKAADVKISQSVPLDLEDESIIHEIGVPAHIKGYMYLREAINMVVDNIELLSAVTKELYPSIAKKYNTTASRVERAIRHAIEVAWSRGQVDTINKLFGYTIHNGKGKPTNSEFIAMIADKLRLKNKVKNVAQ
What is the function of this protein?
May play the central regulatory role in sporulation.  It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress.  Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process (By similarity).
What are the official names of this protein?
Stage 0 sporulation protein A homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_SHEPA
Sequence: MKPLNVIFAGTPDFAARHLQALIDSEHNVIAVYTQPDRPAGRGKKLQASPVKALALENDIAVFQPKSLRDEDAQAELAALNADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDTETGVTIMQMDIGLDTGDMLLKTLLPIEDNDTSSTLYEKLAEQGPTALVEALAGIAEGTLPAEKQDESLANYAEKLSKEEARLDWSKPASALWREIRAFNPWPVSHYEHEGNTIKVWQSSVSDETSSQQPGTILSADKSGISIATGEGVLTITQMQLPGKKPLSVADILNSRADWFTPGTVLASTDNQEA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: IF1A_SULTO
Sequence: MAKKKTNEQPSVKEVPKPAEGEVICVVKKMLGAEHVQVICLDGKERLGRIPGKMKKKMWVKEGDVVLAAPWDFQPNKCDIIYKYSESEVRRLEEEQVVSADIIEQLRG
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: UREE_PSEPK
Sequence: MIVLSRRISEPGTRVVSGTVTLDVDSRIKSRLRVTLDDGREAGLMLERGHLLRGGELLADAEGTQLIRVLAAPEAVSTVRCADPHLLARAAYHLGNRHVPLQIEPGLLRFQHDHVLDDMLRGLGLTVEAEQAPFEPEAGAYQSAPHGHSHSHAHGHDHPFVRLPAHS
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TVP23_YEAS7
Sequence: MDQARNFYNTILKSSHPLLLSFHLAGKAVPIVFYIIGSMFLNFTPQFITVVLLLSFDFYLTKNITGRKLVQLRWWYDSTDVNKDSNFTFESYKQYAPGPPINAIDSKLFWWSMYVTPVIWGVFAVLCLLRLKIFYLILVIVAMCLTAWNTYGFRCCDRWEPNSGQSDGQDTNNWFALPSVPGFENLSRLANIQSFFQRQ
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP23, TLG2 compartment vesicle protein of 23 kDa.
What is the protein family that this protein belongs to?
Belongs to the TVP23 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: MED16_HUMAN
Sequence: MCDLRRPAAGGMMDLAYVCEWEKWSKSTHCPSVPLACAWSCRNLIAFTMDLRSDDQDLTRMIHILDTEHPWDLHSIPSEHHEAITCLEWDQSGSRLLSADADGQIKCWSMADHLANSWESSVGSLVEGDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVATADGSSASPVQFYKVCVSVVSEKCRIDTEILPSLFMRCTTDLNRKDKFPAITHLKFLARDMSEQVLLCASSQTSSIVECWSLRKEGLPVNNIFQQISPVVGDKQPTILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFHDGSVHIVHRLSLQTMAVFYSSAAPRPVDEPAMKRPRTAGPAVHLKAMQLSWTSLALVGIDSHGKLSVLRLSPSMGHPLEVGLALRHLLFLLEYCMVTGYDWWDILLHVQPSMVQSLVEKLHEEYTRQTAALQQVLSTRILAMKASLCKLSPCTVTRVCDYHTKLFLIAISSTLKSLLRPHFLNTPDKSPGDRLTEICTKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLASLPNQGSLLRPGHSFLRDGTSLGMLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPASEPDEALVDECCLLPSQLLIPSLDWLPASDGLVSRLQPKQPLRLQFGRAPTLPGSAATLQLDGLARAPGQPKIDHLRRLHLGACPTEECKACTRCGCVTMLKSPNRTTAVKQWEQRWIKNCLAVEGRGPDACVTSRASEEAPAFVQLGPQSTHHSPRTPRSLDHLHPEDRP
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 16, Mediator complex subunit 16, Thyroid hormone receptor-associated protein 5, Thyroid hormone receptor-associated protein complex 95 kDa component, Trap95, Vitamin D3 receptor-interacting protein complex 92 kDa component, DRIP92.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAD51_SOLLC
Sequence: MEQQHRNQKSMQDQNDEIEDVQHGPFPVEQLQASGIAALDVKKLKDAGLCTVESVVYAPRKELLQIKGISEAKVDKIIEAASKLVPLGFTSASQLHAQRLEIIQITSGSKELDKILEGGIETGSITEIYGEFRCGKTQLCHTLCVTCQLPLDQGGGEGKAMYIDAEGTFRPQRLLQIADRYGLNGPDVLENVAYARAYNTDHQSRLLLEAASMMVETRFALMIVDSATALYRTDFSGRGELSARQMHLAKFLRSLQKLADEFGVAVVITNQVVAQVDGSAVFAGPQIKPIGGNIMAHASTTRLALRKGRAEERICKVVSSPCLAEAEARFQISVEGVTDVKD
What is the function of this protein?
Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity.  Underwinds duplex DNA (By similarity).
What are the official names of this protein?
DNA repair protein RAD51 homolog.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLSA_CLOTE
Sequence: MMQSKIESIIEECRKYTREGEVASYIPELKKADKDALGIYIDKLDGNEFCAGDYDTKFTIQSISKIIALIIAIMDNGMEKVLSKVGVEPSAYSFNSIVTLEVKNANKPLNPMINAGAIATVSLIKGNSPEEIIERILEFTRKVTGNKNIKVNEEVYQSEKKTGDRNRSLAYFMKGTGIIEKDVEKVLDAYFQQCSIEVTCKDIAKIASFLANDGVLPSTGERIIPAEVAKIVKAVMVTCGMYDASGSFAVKVGIPSKSGVGGGILATVPGVMGIGVFGPALDKKGNSIAGVKILERLSEELNLSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: AROC_STRP1
Sequence: MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHHILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGAGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.