PharMolix/UniProtQA huggingface dataset:
Protein: YB11A_YEAST
Sequence: MESQQLSQHSPIFHGSACASVTSKEVQTTQDPLDISASKTEECEKVSTQANSQQPTTPPSSAVPENHHHASPQAAQVPLPQNGPYPQQRMMNTQQANISGWPVYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKSNMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELTFLCHTFQLFAPSQFLPPWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLATLHYNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLPYARHRCIHMTVADLFSDIHSMYEEQQESKRNKSTYRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNNSQSRTARAHNVSTFNNSPGPDNDLIRGSTTEPIQLKNTHDLHLRPGTY
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty1-BL Gag polyprotein, Gag-p49, Transposon Ty1 protein A, TY1A, TYA, p58.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_PARL1
Sequence: MRPGFSVPGESGRERPAFPLPCACGTLRPMPPPAKKPAQKKKPLPLLPDFRFEIEEGAPARLVCGVDEAGRGPLAGPVVAAAVIIDLTRCPEGLNDSKKLDAARRADLLAELADCAEIGVGIASVEEIDEINILHATMLAMTRAVASLPRAPHIALIDGNRCPPSLACASRAVIGGDALARSIAAASIVAKVTRDRMMAALAETHPGYGFEKHMGYSTPEHFDALSRLGPCAIHRRSFAPVRKMLSPGLEEGLDLVSGESVNLLIQKAY
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23A_FRIAG
Sequence: MAPPAKVAKKPDGKAQALKVAKAVKSGVSTLQKKAKKIRTSVTFHRPKTLKKDRNPKYPRISAPPRNKLDHYQILKYPLTTESAMKKIEDNNTLVFIVDIRADKKKIKAAVKKMYDIQTKKVNTLIRPDGTKKAYVRLTPDYDALDIANKIGII
What is the function of this protein?
This protein binds to a specific region on the 26S rRNA.
What are the official names of this protein?
60S ribosomal protein L23A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: JZ11C_CHIGU
Sequence: MKVSVLITLAVLGVMFVWASAAELEERGSDQRDSPAWLKSMERIFRSEERECRKMFGGCSVDSDCCAHLGCKPTLKYCAWDGTFGK
What is the function of this protein?
This toxin acts as a voltage-dependent gating-modifier (PubMed:25240294).  It inhibits the sodium conductance (IC(50)=124 nM) and slows the fast inactivation (EC(50)=1180 nM) of Nav1. 5/SCN5A (PubMed:17176080, PubMed:25240294).  It significantly shifts the activation to more depolarized voltages and decreases the deactivation of Nav1. 5 currents upon extreme depolarization, but only slightly affects voltage-dependence of steady-state inactivation (PubMed:17176080, PubMed:25240294).  In addition, this toxin causes an approximately five-fold decrease in the rate of recovery from inactivation and an approximately 1. 9-fold reduction in the closed-state inactivation rate (PubMed:25240294).  This toxin integrates the functions of site 3 toxins (alpha-scorpion toxins) with site 4 toxins (beta-scorpion and spider toxins) by targeting multiple sites on Nav1. 5 (PubMed:25240294).  Also shows inhibition of voltage-gated potassium channels (5 uM completely inhibits Kv2. 1/KCNB1, whereas 5 uM moderately inhibits Kv4. 2/KCND2 Kv4. 1/KCND1 channels) (PubMed:17176080).
What are the official names of this protein?
Kappa-theraphotoxin-Cg1a 3, Kappa-TRTX-Cg1a, Jingzhaotoxin-11.3, JZTX-11.3, Jingzhaotoxin-XI.3, JZTX-XI.3, Peptide F4-13.64.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 28 (Jztx-11) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TI214_ARAHI
Sequence: MVFQSFILGNLVSLCMKIINSVVVVGLYYGFLTTFSIGPSYLFLLRARVMDEGEEGTEKKVSATTGFIAGQLMMFISIYYAPLHLALGRPHTITVLALPYLLFHFFWNNNKHFFDYGSTTRNEMRNLRIQCVFLNNLIFQLFNHFILPSSMLARLVNIYMFRCNNKMLFVTSSFVGWLIGHILFMKWVGLVLVWIQQNNSIRSNVLIRSNKYKFLVSELRNSMARIFSILLFITCVYYLGRIPSPIFTKKLKGTSETGGTKQDPEVSTEEAPFRSLFSEEREDLDKIDEMEEIRVNGKEKINKDDEFHVRTYYNYKTVSENRDGNKENSNLKFLKIKEDPFFFLWFEKPFVTLVFDYKRWNRPNRYIKNDKIENTVRNEMSQYFFYTCQSDGKERISFTYPPNLSTFFEMIQKKISSFTRAKAPSDQVYAYWSLLNEKKKENLKNEFLNRIEALDLDKERSFENILEKTTRFCHNETKKEYLPKLYDPFLHGISRGKIKKLLPFKKITDINIGIGGSWINKIHGILLRINSHKFEQTIEKFTRKSLSIEKKLSFFSEPQEEKINSEEEIKIFKFLFDVVITDNNNKTLIKNFIDFHEINKNVPRWSYKLTSELEELEGENEENVPTEPGIRSRKAKSVVVFTDKEPHNGIFTNLKDNQNSDQKDEMALIRYSQHSDFRRDLIKGSMRSQRRKTVIWDFFQAKVHSPLFFDRIDKLFFFSFDFWGLKKKIIRNFMWKKKKKEFLKKEDEQSKRKETRRIEIAETWDSFPFSQIIRGSLLVTQSILRKYIILPLLIIIKNSTRALLFQVPEWSEDLKDWKREMHVKCTYNGVQLSETEFPRNWLTDGIQIKILFPFYLKPWHKLKVQSSQKARLKKIKDKGEKTDFGFLTVWGMETELPFGSAKKKRSFFEPIFKELKKRIKKFKTKPFRVLSIFKERATIFLKVTKERKNWIIKNLLFRKGKRKNISKQNIIPLFGVREIDELNETKKDSIMSNQMIYELSGQKKSMEWPNSSLNENKIKNLIDRIKIIKNQTEEISKEKENLTNRCNKPRYDSQIIASSKKRWQAFKRKNIRLIRKSFFFFKFCIEQLSITFFLGIINIPRITTQLQLFFESTKTILDKYIYKNEENGEKKKNQKNTIYFISTLKNLISKNKKFSYDLCSLSQAYVFYKLSQIQVSNFSKLKAVLEYNICITSFFVKNQIKDFCQEQGIFHYELKDKTFFNSEVNPWKYWLRSHSQYNLPWIAWARLVTQKWKKKINQDFLVLNTSLIKTDLYEKNKIDNYKKQQFFEANSLLNSKHNLKKDYIYNSFCYRSIHSREKKFDMSMSIGITPDNCLVSSFLEKYNIQVIGEIGHRKYLDWRILNFWFRKKVNIGLLIDTKSKKKYIKTKVQNYKKIDKITKTDLANQKSFFFDWMGMNEERLNHRITNFAFFFFSEFFLFSSTYKTKPWVIPIKLLLFNFNEKKNVNKKITLKKKGFIPSNEKGPLRFFNLNKEENELVGQGELESDNEKKRNPESALSNQEKNIEKNYAESKIKKRQNKKQYKSHTEAELYLFLTRYSRFQLRWNCFFNQKILNNIKVYCLLVRLKNPNEIAISSIERGELSLDILMIEKNFTFSKLMKKGILIIEPVRLSVKNDGQLIIYRTVGISLVHKNKQKISKRYKKKSYIDKKNNYDFFIPENILSPKRRREFRILICFNLKKKNARDRNSRFDKNIQNLTTVLHKKKDLYKDKKTLIKLKSFLWPNFRLEDLACMNRYWFNTTNGNHFSMIRIHMYARFQIR
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: NANE_CLOPS
Sequence: MLDVVKGNLIVSCQALSDEPLHSSFIMGRMAIAAKQGGAAAIRAQGIDDINEIKEVTKLPIIGIIKRNYDDSEIYITPTMKEVDELLKTDCEMIALDATKRKRPNGENIKDLVDAIHAKGRLAMADISTLEEGIEAEKLGFDCVSTTLSGYTPYSKQSNSVDFELLEELVKTVKIPVICEGRINTPEELKKALDLGAYSAVVGGAITRPQQITKRFTDILK
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: MINC_NEIGO
Sequence: MMVYIMNAFDIKSTKMDVLSISLHTSDLFDLEDVLVKLGKKFQESGVVPFVLDVQEFDYPESLDLAALVSLFSRHGMQILGLKHSNERWAAVAMKYHLLFCLSHSENVKELGQVEVQKTEDGQKARKTVLITSPVRTGQQVYAEDGDLIVTGAVNQGAELIADGNMHIYAPMRGRALAGAKGDTSARIFIHSMQAELVSVAGIYRNFEQDLPDHLHKQPVQILLQDNRLVISAIGSE
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: CXB2_MACMU
Sequence: MDWGALQTILGGVNKYSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKNEFKDIEEIKTQKVRIEGSLWWTYTSSIFFRVVFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKKPV
What is the function of this protein?
Structural component of gap junctions.  Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells.  They are formed by the docking of two hexameric hemichannels, one from each cell membrane.  Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
What are the official names of this protein?
Gap junction beta-2 protein, Connexin-26, Cx26.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Beta-type (group I) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Colocalizes with GJB4 at gap junction plaques in the cochlea.
Protein: Y986_METM5
Sequence: MKFRKGRPKIPRLISEEPQFKLFKPAGTPGIELESEVLSFEELESLRLVDYLNQPHEEAADAMGISRRVFWNILKSARKKVADALINGKMIDIGGGYYKIRECNYEDECQRGRNCRYGVSNCLTLKKDSE
What are the official names of this protein?
UPF0251 protein MmarC5_0986.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: PNSL2_ARATH
Sequence: MSSFTTTNTPPPYLLRKIYHRRVNQPFSVVCCTGEPQQDIFTRRRTLTSLITFTVIGGATSSALAQEKWGTRSFIKEKYFMPGLSPEDAAARIKQTAEGLRDMREMLDHMSWRYVIFYIRLKQAYLSQDLTNAMNILPESRRNDYVQAANELVENMSELDFYVRTPKVYESYLYYEKTLKSIDNVVEFLA
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (Probable).  Required for both formation and activity of the chloroplast NAD(P)H dehydrogenase (NDH) complex (PubMed:20430763, PubMed:20460499).
What are the official names of this protein?
Photosynthetic NDH subunit of lumenal location 2, chloroplastic, PsbQ-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the psbQ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with the chloroplast NAD(P)H dehydrogenase/photosystem I (NDH/PSI) supercomplex.
Protein: RNH2_DESPS
Sequence: MKDIIPLLSQLPQDNFFLERSLHNLGYDIIAGTDEVGRGPLAGPVIAAAVILPADCDHHLFQDSKILSHKKRVHLFQLLTEIDAFIGIGTVSEKIIDEINILQASLLAMKLAIEDLASNCSRPSFLLVDGKFKVPIDLAQVALIKGESKSASIAAASIVAKVTRDRYMQDLHSQYPQYGFNTNSGYPTKKHREAIGEFGITCYHRRSFKGVKEYVDISQEKGGRG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB1_RUBXD
Sequence: MAPAELALTLAAAGAGSVLRYLLGGWVAHRMGPEFPWGTLAVNALGCLGLGLLQGAAPHDRALLLVLGSGLLAGFTTFSTLMLETANLATAGERDRAFSNIVGTLALGLFALSAGARAGAWAAG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YNQA_SCHPO
Sequence: MNKHFAKLSQWTGEKFGFDRQKTTLSDDFCSLKGETDAWLVGMDKIHRSCTRWVRNMDKRKGLLDEKDKQLPVTHVGSSFVELGQALSHSSSNSHTYIMYGKSMVEIGHLQEEFMDYLNNSFLANLENSLAEFKALDVKEKKMENRRLVFDALSTKIQKAKKEESKLEEDLRNARAKYEESLEEFEDRMVQLKELEPDRVENVVRLLQMQIRFHQKSLDLLKGLEMNGFSKKRDNVNIPKRTYSARSIPSNISSTNVATTPSNTIFEMDDTLKADSSSNEYHSPTNTLPSYHTEADLDNSSIASSNRTQHTEDNYNKDVSDAQNSLGQSAVDLTTPSSPPIPRHTKPKLSTTQSTPVKPASLQSEEDIQLSFKQPELSASSAELDEKLKSQCNVSPSPSNISDAPPSKLNRSYSSPLASISSRKVVRMKYSFEPETENELKLKKGDLLLVLKEIDEGWWVGEKLGEDGVFTGNTGMFPSNYCVPAHPWDKTFRAFLKKGFK
What are the official names of this protein?
Uncharacterized protein C19C2.10.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at the barrier septum.
Protein: RLME_PSEFS
Sequence: MARSKTSLKWLQEHFNDPYVKKAQKDGYRSRASYKLLEIQDKDKLIRPGMSVIDLGAAPGGWSQVTSRLIGGQGRLIASDILEMDSIPDVTFVHGDFTQDTVLAQILEAVGNSQVDLVISDMAPNMSGLPAVDMPRAMFLCELALDLAGRVLRPGGDFLVKVFQGEGFDEYHKNIRKLFDKVQTRKPDSSRDRSREQYLLCRGFRGVEGAASEERF
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LV746_HUMAN
Sequence: MAWTPLFLFLLTCCPGSNSQAVVTQEPSLTVSPGGTVTLTCGSSTGAVTSGHYPYWFQQKPGQAPRTLIYDTSNKHSWTPARFSGSLLGGKAALTLLGAQPEDEAEYYCLLSYSGAR
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 7-46.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: RS182_MYCGI
Sequence: MKRARRAAPLPKKRRNMFAQLGIERVDYKDTSTLRQFLSERGKIRSRTVTGLTVQQQRQVTIAVKNAREMALLPYPGQG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PNP_BACAA
Sequence: MSQEKQVFSIDLAGRQLTVETGQLAKQANGAVLVRYGDTAVLSTATASKEAKNVDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAILASRLIDRPIRPLFADGFRNEVQVVNIVMSVDQDCSSEMAAMLGSSLALSISDIPFEGPIAGATVGRINGEFVINPTVEQQEQSDIHLVVAGTKDAINMVEAGADQVPEETMLEAIMFGHDEIKRLIAFQEEIVQAVGKEKSEVKLYEVDADLNQAVREMAEKDMHSAIQVHEKHAREDAINEVKKRVIEHYEAQEADADTLGQVNEILYKIVKEEVRRLITVEKIRPDGRKGDEIRPLASEVGILSRTHGSGLFTRGQTQALSICTLGALGDVQILDGLGVEESKRFMHHYNFPSFSVGETRPMRGPGRREIGHGALGERALEPVIPSEKDFPYTVRLVSEVLESNGSTSQASICGSTLAMMDAGVPLKAPVAGIAMGLVKTGEHYTILSDIQGMEDHLGDMDFKVAGTAHGVTALQMDIKIDGLSREILEEALQQAKVGRVHILNHMLSVIAEPRTELSAYAPKIITMTINPDKIRDVIGPSGKQINKIIEETGVKIDIEQDGTVFISSINQEMNDKAKKIIEDIVREVQVGEIYEGKVKRVEKFGAFVELFSGKDGLVHISELALERVGKVEDVVKIGDVITVKVIEIDKQGRVNLSRKVLLKEEQEKEAAKEENKQEQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_BRUMB
Sequence: MQRNGLIGDTIRSLGFLSRLPLPQGWFDNTDDSLPRNARAFPLAGGILGLLAGVALLIANAISLPPLAAALIAIGALAAMTGALHEDGLGDTADGFFGASTPDRRLDIMKDSRIGTFAALTLVIWTGVKASLLMAIIARAGAGYALLALIGTEAASRAGMLAFWHALPSARPGGLADSMGQPQWETVVCGCGLGLALLAIGFLPSGGMVALINALVLMTVVLFGFARLCMAKIGGRTGDTLGAAQQIGSLAALIGLVMAL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF2_ECO55
Sequence: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNC1_NATPD
Sequence: MLSVSGLTKRYGDERALDDVSVDLQRGELTVLVGRSGAGKTTLLRCLDGLEQPDDGTIELDGRAPATTDVALVFQAGALVDSKSALSNVLDGALGRLPSWRELLGVYPADEKRAAIARLHDVGLGGYADRRVGTLSGGQRQRVGIARALQQEPAVLLADEPVASLDPETGRDVLERVAAVVRDDDLIGVVSLHQPRLAEPIADRYLGLADGRLVLDRPAAALDREDITAVYDD
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AROK_BACC2
Sequence: MKSIYITGYMGAGKTTIGKALSQELQMDVVDTDQKIEEKQKKAIRDIFAEEGEMTFREYESEMLRSLPVHNVIITTGGGIIERAENRKWMKENGTVVYLYCDPNVIAERLREDTTRPLFQKKDIDAFVKKFESRRAYYEEAHIHIDTTNKSVKQIMNELKEKINV
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEN1_YEAST
Sequence: MSQLVLDLKCLKDKIATNYDIHNNVYGGNGMEPNIIHPSKRFRIVVRLVDFLFCKSDEEFIKGFFCQMIVRNLHCLNSTNGAEEMRLYMSERLFSAHKDDLRLINGQVLDVRIGVWYGIHQSPPIFEIIDFKILSRNDVRDFCEFVKSPLGEKFLNISNS
What is the function of this protein?
Has a role in telomere length regulation and telomere end protection.  Acts as an inhibitor of telomerase loading through its interaction with CDC13.
What are the official names of this protein?
Telomere length regulation protein TEN1, Protein telomeric pathways with STN1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: MTGA_NEIME
Sequence: LDYRWMPYKRISTNLKKALIASEDARFAGHGGFDWGGIQNAIRRNRNSGKVKAGGSTISQQLAKNLFLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSIEWHYGVFGAEAASRYFYQIPAAKLTKQQAAKLTARVPAPLYYADHPKSKRLRNKTNIVLRR
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PYRD_ERWT9
Sequence: MYYPFVRKALFKLDAERAHELTLQQLKRLSGTPLTKLIHQSLPFKPVNCMGLTFKNPLGLAAGLDKNGECIDAFGAMGFGFIEIGTVTPRPQPGNDKPRMFRVVEAEGIINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVEQGKEDYLVCMDKIYPYAGYITINISSPNTPGLRSLQYGEALDDLLAAIKTRQSELQARHHKYVPIAVKIAPDLSEEELIQVADSLVRHHIDGVIATNTTLDRELIKGLKYADEAGGLSGRPVQLRSTEIIRRLSAELQGRVPIIGVGGIDSLISAREKIAAGASLVQIYSGFIYKGPPLIKEIVTNL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPB_SALTO
Sequence: MMTVSATAEGPAGTKAATGRVVRVIGPVVDAEFPRDAMPDLFNAMHVDVTLSGGEKTLTLEVAQHLGDNLVRAISMQPTDGLVRGVEVRDTGSPITVPVGDTVKGHVFNAIGECLNLEPGETLSPDDHWQIHRKAPAFADLEPKTEMLETGIKVIDLLAPYVKGGKIGLFGGAGVGKTVLIQEMITRVARNFGGTSVFAGVGERTREGNDLIAEMTESGVIDKTALVYGQMDEPPGTRLRVALSALTMAEYFRDVQKQEVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSVRGQAITSLQAIYVPADDYTDPAPATTFAHLDATTNLERSISDKGIYPAVDPLASSSRILAPEFVGQEHFTVATEVKRILQRYKDLQDIIAILGIEELSEEDKLTVGRARRIERFLSQNTYAAEQFTGMKGSTVPIKETIDAFKKISEGEYDHFPEQAFFMCGGLEDLERKAKELMAEG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.