PharMolix/UniProtQA huggingface dataset:
Protein: RNP4_METBU
Sequence: MYMSRMKKKQKNIIKDVASERIERLFKLAAEEYSSNPGRSDRYVHLARRIGMKYRIRFPSPLKRKMCRGCSSYLVPGSSSRVRLHGRYMTITCLKCGREMRIPYHLKE
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX15A_ODOMO
Sequence: MKLSALSLAFAIILMMTIMYTKADADASADAEADADAEAEAIWGALLGTLIPAITSAIQGK
What is the function of this protein?
Acidic peptide with potent hemolytic activities (94. 8% at 50 uM).  It also shows low antimicrobial activities against E. coli (MIC=50uM), as well as histamine-releasing activity (28. 3% at 10 uM).  Does not have activity against S. aureus, and S. cerevisiae.
What are the official names of this protein?
U-poneritoxin(01)-Om5a, U-PONTX(01)-Om5a, Pilosulin-like peptide 5, PLP5, Poneratoxin.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF_WOLSU
Sequence: MKGKYFIPCLLLPTMMLASGGGGETDIVERTINFVIFIAIFYYLAADKIKAIFVARQESIAAELEKVQEKLKESKKAKEQAQKRFEESKRMAEDVILTAKKEVVLLTQKVEDSTKGDIENLIRQYNDSMEFEKRKAERAIIDEILAELFESDATKLDKSAYSEILLKKVA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RSMA_PARXL
Sequence: MSTSRQQQGRHQGHIARKRFGQNFLVDMGVIDSIVDVIRPQRGERMVEIGPGLGALTEPLIERLATPEAPLHAVELDRDLIGRLKTKFGDLLELHAGDALAFDFGSLAAPGDKASLRIVGNLPYNISSPLLFHLTAFAHCVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVIDKQLDVPPEAFNPPPKVDSAIVRMIPYELHELPPVDERVLGELVTAAFSQRRKMLRNTLAAYRDSVDFEGLGFDLQRRAEDVPVAEYVRVAQIVAASKA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS2_KITGR
Sequence: MALLTRIRGPRDLDRLTPAQLAELAEEIRAFLVEEVSKTGGHLGPNLGVVELTLAMHRVFDSPRDRILFDTGHQSYVHKLLTGRQDFSRLKMKGGLSGYPSRAESEHDVIENSHASTVLGYADGLAKANKIQGHKDRPVVAVIGDGALTGGMAWEALNNIADSQDLPIVIVVNDNERSYSPTIGGLANHLATLRTTQGYERFLSWGKDALQRTPVVGQAMFDTLHGAKKGLKDFIAPQGMFEDLGLKYLGPIDGHDLQALESAFTKARNFGGPVIVHCITEKGRGYHAAENNDEDRFHAVGVIHPDTGLPVKTSGKDWTSVFGEEMVALGRERRDLVAITAAMLHPVGLAPFAKAYPERIFDVGIAEQHAAVCAAGLATNGLHPVVAVYATFLNRAFDQVLMDVALHKLGVTFVLDRAGVTGTDGASHNGMWDMSILQVVPGLRLAAPRDAEQVRLQLREAVEVADAPTVVRYSKGNVGPAVPAVGTVGGMDVLRRPEADSADEAADVLIVSIGAMAPTCLEAAELLAQQGISSTVVDPRWVKPVDAALPGLAAQHRLVVTVEDNGRAGGVGSAIAQALRDADVDVPLRDFGIPQEFLDHASRGEILDEIGLTAPAIAKKIEALVSTRSFARS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase 2, 1-deoxyxylulose-5-phosphate synthase 2, DXP synthase 2, DXPS 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PG136_VAR67
Sequence: MMPIKSIVTLDQLEDSEYLFRIVSTVLPHLCLDYKVCDQLKTTFVHPFDVFLNNSLGSVTKQDELQAAISKLGINYLIDTTSRELKLFNVTLNAGNIDIINTPINISSETNPIINTHSFYDLPPFTQHLLNIRLTDTEYRARFIGGYIKPDGSDSMDVLAEKKYPDLNFDNTYLFNILYKDVINAPIKEFKAKIVNGVLSRQDFDNLIGVRQYITAQDQPRFDNTYAIADAARHYGVNLNTLPLPNVDLTTMPTYKHLIMYEQYFVDDYDRVPIYYNGNRVIFDDEIINFCISMRYQSLIPRLVEFFPDIPVNNNIVLHTRDPQNAAVNVTVGLPNMQFVDINRNNKFFINFFNLLAKEQRSTAIKVTKSMFWDGMDYEEYKSKNLQDMMFINSTCYVFGLYNHNNTTYCSILSDIISAEKTPIRVCLLPRVVGGKTVTDLISETLKSISSMTIREFPKKDKSSIMHIGLSETGFMRFFQLLRLMADKPHETAIKEVVMAYVGIKLGDKGSPYYIRKESYQDFIYLLFASMGFKVTTRRSIMGSNNISIISIRPRVTKQYIVTTLMKTSCSKNEAEKLITSAFDLLNFMVSVSDFRDYQSYRQYRNYCPRYFYAGSPEGEETIICDSEPISILDRIDTRGIFSAYTINEMMDTDIFSPENKAFKNNLSRFIESGDITGEDIFCAMPYNILDRIITNAGTCTVSIGDMLDNITTQSDCNMTNEITDMINASLKNTISKDNNMLVSQALDSVANHSKQKIGDLRQSSCKMALLFKNLATSIYTIERIFNAKVGDDVKASMLEKYKVFTDISMSLYKDLIAMENLKAMLYIIRRSGCRIDDAQITTDDLVKSYSLIRPKILSMINYYNEMSRGYFEHMKKNLNMTDGDSVSFDDE
What is the function of this protein?
Core protein 4a is the most abundant virion protein.  Major component of the virion core that undergoes proteolytic processing during the immature virion (IV) to mature virion (MV) transition.
What are the official names of this protein?
Major core protein OPG136 precursor, p4a, Virion core protein 4a precursor.
What is the protein family that this protein belongs to?
Belongs to the orthopxvirus protein OPG136 family.
Protein: UVRC_PSEPF
Sequence: MTEAFDSGAFLSTVSGRPGVYRMFDSDARLLYVGKAKSLKKRLASYFRKTGLAPKTAALVGRIAQVETTITSNETEALLLEQTLIKEWRPPYNILLRDDKSYPYVFLSDGQFPRLSIHRGAKKAKGKYFGPYPSAGAIRESLSLLQKTFFVRQCEDSYYKNRTRPCLQYQIKRCKAPCVGLVEPEVYAEDVRHSVMFLEGRSHALTNELSTAMEEAAINLEFERAAELRDQIALLRRVQDQQSMEGGTGDIDVIAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVAEVMAAFLGQYFISSPERDLPSELIVNVVHEDFPALIEAIQALRGRELSISHRVRGTRARWQQLAVTNAEQALGARLANRQHVAARFEALAEVLNLDEPPQRLECYDISHSSGEATVASCVVFGPEGAIKSDYRRYNIEGVTAGDDYAAMHQALTRRFSKLKEGEGKLPDILLVDGGKGQLSMARDVLNELAVPDLILLGVAKGATRKAGFETLYLNDAANEFTLRGDSPALHLIQQIRDEAHRFAITGHRARRGKTRRTSTLEGVAGVGPTRRRDLLKHFGGLQELSRASIEEIAKAPGISKKLAESIYANLHSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_HALMA
Sequence: MQATIYDLDGNTDGEVDLPDVFETPVRSDLIGKAVRAAQANRKQDYGSDEYAGLRTPAESFGSGRGQAHVPKQDGRARRVPQAVKGRSAHPPKTEKDRSLDLNDKERQLAVRSALAATADADLVADRGHEFDRDEVPVVVSDDFEDLVKTQEVVSLLEALDVHADIDRADETKIKAGQGSARGRKYRRPASILFVTSDEPSTAARNLAGADVATASEVNTEDLAPGGAPGRLTVFTESALAEVAER
What is the function of this protein?
Forms part of the polypeptide exit tunnel, in which it helps forms a bend with protein L22.  Contacts the macrolide antibiotic spiramycin in the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4, Hl6, Hmal4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CRCB_ALTMD
Sequence: MPQGLALYCFIAAGGATGACLRYFVTTSVDSLFGKHMPFGTLTVNVVGSFALALLYGVIERYDLSDSPYRALIGVGLLGAFTTFSTFSVETLTLLENELWLKAAANVFLNVGACLLAGWLAIELMKG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCNH_ECHMU
Sequence: MAYVTSTQLYNWRFTQDELANQRQECNAAVRRRLSAQYRAKAEVKGGDVPAEPTFLTAEEEFIIVKRYIFAMKELFHQFSDSGLPVDVFGFAATYLKRFYLNNSVMDYFPREMMLTALYLACKAADYPLGLQTFAAHIPRNREHYSEIVVHSELFLMEKLQYDIWIHTPYRPLSGLLVDLLAYRKTQLGEPMTIEAGEVATADMMTSLKKEGYEIIHKWFQTDLCLTHSPSQFALAVLLELGQKHPDLGVEKFVKNSVCEYNSSDELMEQKWTALNEKMEQIQTMIGEFEFLSDLTYGSDLEAVLMQCRNPLYDPLSEEYAAAKEQAEKLMSFLD
What is the function of this protein?
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex.
What are the official names of this protein?
Probable cyclin-H.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_MYCGA
Sequence: MLDKNLLKTNSKEIREQLKSRSFNLDWYDEFLRLEKQLSTLLRTIEKLNEQKNINAKKAATTESDAQRKKLIQEGGLLRAELEKNEAKYNEIKEDFDYIYQRIPNLPTEDVPIGKDEKENVEMFKSRKPTFFDFKPLPHYELATKLEMIGLDVASKITGSRFSIYKKDGARLMRAIQQFCLYVNADKYEEYLPPVIVNKDSYYGSGQFPKFVEDVFKLEGTNYYLASTAEVQLVNLHRNEILKEADLPKYYTASTACFRSEAGSAGKDTKGLIRQHQFYKTELVKIVHPSTSKQEHEAMAKDAEKILELLELPYRRMVLCTGDMGFSATKTYDLEVWIPSENKYREISSISNCGDFQARRANIKFKDAISKKNLYVHTLNASALAHDRLFVAIVENYQQKDGSIKIPKALVKYFGKEYIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JMJCB_DICDI
Sequence: MFNNTNKIIEIERNNNKNIEKELFYKYLNENEPIIFTKFSTDWEALSKWNDPNYLINIIGNDHIVDVNKCSFGGYYKDIIKIKFSEFISKSINNQFDNFDLNGNKIKKVNKPYLRNFEMFEDFPIFEQDINCDIIFDKDKHNLIVKRAFIGSVGSATSFHIDTGDNLVTVIKGCKFIVMISPNDSKFLDFQKSREIEISFNQNDNDGIPLEYHPAFSNCKYIYKTLLRKGESLFIPNNWTHYVHNISDHDDNFNEDNNNNNNCNNNNNLTISVSCWGKSIYDLVVG
What are the official names of this protein?
JmjC domain-containing protein B, Jumonji domain-containing protein B.
Protein: TOLB_BURPS
Sequence: MSLMTKLGFRALVASCLIAAGGAAHAQVNVLITGVGSTQFPIATANFVNEASLPQQVTSVVRGDLARSGKFSNVDAGSTPVPETASVDFGAWKAKGANAFVAGSVNREPNGQYKVNFILYDTVKQQSLGGLSLTTSNDNEGMRKTGHKIADYIYQKLLGVRGVFNTRLSYVQRTGNVYKLLISDSDGQNAIPALTSKEPIISPAWSPSGTKVAYVSFELRKPVVYIHDLPTGRRYVISNQKGNNSAPAWSPDGQTLAVALSLTGNTQIYSVSSTGTGLRRLTRSSSIDTEPFYSPDGKWIYFTSDRGGAPQIYRMPAEGESAGAAQRVTFTGSYNTSPRVSPDGKLLAYISRTGGGFKLYVQDLQSGAANAVTNTTRDESPSFAANGQYILYATQSGGRSVLAAVPSDGSAPPQILSVQGGAIREPSWGPFMQ
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PNP_COXBN
Sequence: MNKIRKTFQYGKHEVTFETGEMARQATGAVVVRMGDTVLLVSVVAKKEAEEGRDFFPLTVNYQEKTYAAGKIPGGYFKREGRPTEKETLTSRLIDRPLRPLFPKGFTNEVQVIATVLSVDSKVPTDIPAILGASAAIGLSGIPFNGSLGAARVGYRGGEYLLNPSLDELKDSALDLVVAGTRDAVLMVESEAQELPESVMLGAVLHGHQAMQVAIQAIAEFIQEAGGAKWEWEPPTVNTALEKWVVEKSEAPLKKAYQIQEKTARQAQIQAIRDQLLADRAAEREGEENAVNEHELAVIFHELERRIVREQILTGQPRIDGRDTKTVRPITVKVGVLPRSHGSALFTRGETQALVVTTLGTERDAQSIDDLDGDRQEEFIFHYNFPPFCVGEVGFMSGPKRREIGHGRLAKRAVVPVVPTLDKFPYVIRVVSEILESNGSSSMASVCGSSLALMDAGVPTKAPVAGIAMGLIKENDKYAVLSDILGDEDHLGDMDFKVAGTSNGVTALQMDIKIEGITKEIMEQALDQAKEGRLHILSIMNKVLDKPRSQVSDLAPQYVTMKINPEKIRDVIGKGGVVIREITEATNCAIDISDDGTIKIAAHTTEEGEAAKRRIEELTAEVELGKVYEGTVVKITDFGAFVQILPNTQGLVHISQIAQERVENVRDYLEEGQVIRVKVIEIDRQGRVRLSMKQID
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTPD_MYCS2
Sequence: MTALYPAVEPAPAARPARPRSGGWLWTVPSVRWAAAALALFLTGLAAQLLGAPQAVVWTLYLACYVVGGWEPAWVGVRALRNRTLDVDLLMIVAAIGAATIGQVFDGALLIVIFATSGALEDVATTRTERSVRGLLDLAPEHATLLGDGSQRVVAAADLRPGDVIVVRPGERISADGTVIGGASEVDQSSITGEPLPAAKDVGDDVFAGTVNGSGALRVEVTREPSQTVVARIVAMVTEASATKATTQLFIEKIEQRYSAGVVVATLALLTVPLMFGADLRSTLLRAMTFMIVASPCAVVLATMPPLLSAIANASRHGVLVKSAVAMERLADTDVVVLDKTGTLTAGEPVISRVTVLIDGADVLGMAAAAEQFSEHPLGRAIVAAARGRVVPEAGDFTALPGRGVRARVAGHVVEVVSPAAYAGENAAVREHCAAIENDGGTAVVVLEDGLPVGVIGLADRLRPDAPAAVMQLAQLTKHPPMLLTGDNRRAAGRLAEEAGIADVHAELLPDGKAAAVQKLQRDNTHVLVVGDGVNDAPAMAAAHTSIAMGRAGADLTVQTADVVTIRDELATVPAVIALARRARRVVIANLVMAGAAITTLVLWDLFGQLPLPLGVAGHEGSTILVALNGLRLLSNRAWISPGATPT
What is the function of this protein?
Involved in heavy metal homeostasis.  Probably exports nickel and cobalt ions out of the cell.
What are the official names of this protein?
Probable cobalt/nickel-exporting P-type ATPase, Cation-transporting P-type ATPase CtpD.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMA_SYNC1
Sequence: MKEKNKHILVAMSGGVDSTVAAALLLAQGHQVSGVTMRVWDTEPLGDGREPAHIRDARKVAFDLGIPLHVVDLREEFLQQVVTPFCEEYLSGRTPNPCVLCNRVFKFSRLLREADRLGADALATGHYARIVEHDGLKVLAKGSNRQKDQSYFLFTLTQQQLQRVVFPLGEMSKEEVRTHAERLGLHVAQKGDSQDICFIPDGDYIGFLERQSHATDTEGSIVHVSGKRLGKHRGAYRFTVGQRRGLGIAWPEPLYVVAIDAAKKQVIVGEKEHLHVDRLVTTGTNWIVAQPQQPLQARCRIRYRHQEAPCTLVVLGNDRVEVRFDEPQSGVSPGQAAVFYDEDRVLGGGWIA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_CUTAK
Sequence: MARVKRSVNAKKKRREVLDQASGYRGQRSRLYRKAKEQTLHSATYSFRDRRAKKGDFRSLWIQRINAASRAQGMTYNRFINGLKNAGVEVDRKMLAELAVSDINAFNSLVEVAKANQPQNAAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RBFA_FRAT1
Sequence: MAAEGRVQRVASEFQKVISLLLRTRIKDAKLASATITEVDLSKDLSYAKIYYTCLAIEDAEYIDKAFEKSKGFFRSSIAKSLSLRIVPNLKFIYDTSLDYGMQMEEKIQQALEADSKIIKQDDKSLQENYKQNDKETKAEKLR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTHY_HUMAN
Sequence: MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
What is the function of this protein?
Thyroid hormone-binding protein.  Probably transports thyroxine from the bloodstream to the brain.
What are the official names of this protein?
Transthyretin, ATTR, Prealbumin, TBPA.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: NUOH_PSEE4
Sequence: MSWFTPEVIDVILTVVRAIVVLLAVVVCGALLSFVERRLLGWWQDRYGPNRVGPFGMFQIAADMLKMFFKEDWNPPFVDRMIFTLAPVVAMSALLIAFVVIPITPLWGVADLNIGLLFFFAMAGLSVYAVLFAGWSSNNKYALLGSLRASAQTVSYEVFLGLALMGVVVQVGSFNMRDIVEYQANNLWFIIPQFFGFCTFFIAGVAVTHRHPFDQPEAEQELADGYHIEYAGMKWGMFFVGEYIGIILISALLVTLFFGGWHGPFGILPQVPFLWFALKTAFFIMLFILLRASIPRPRYDQVMDFSWKFCLPLTLINLLVTAAVVLYNTPAVAAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: POL_HV1C4
Sequence: MGARASVLSGGELDRWEKIRLRPGGKKQYRLKHIVWASRKLERFAVNPGLLETSKGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEVRDTKEALDKIEEEQNKSKKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVIEEKAFSPEVIPMFAALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPTPVGEIYKRWIILGLNKIVRMYSPISILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNSATIMMQRGNFRRQGKTVKCFNCGKEGHIARNCKAPRKKGCWKCGREGHQMKDCTERQANFLREDLAFPQGKAREFSSEQTRANSPTRGELQVWGRDNNSLSEAGAERQGTVSFSFPQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYDEV
What is the function of this protein?
Aspartyl protease that mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane.  Cleavages take place as an ordered, step-wise cascade to yield mature proteins.  This process is called maturation.  Displays maximal activity during the budding process just prior to particle release from the cell.  Also cleaves Nef and Vif, probably concomitantly with viral structural proteins on maturation of virus particles.  Hydrolyzes host EIF4GI and PABP1 in order to shut off the capped cellular mRNA translation.  The resulting inhibition of cellular protein synthesis serves to ensure maximal viral gene expression and to evade host immune response.  Also mediates cleavage of host YTHDF3.  Mediates cleavage of host CARD8, thereby activating the CARD8 inflammasome, leading to the clearance of latent HIV-1 in patient CD4(+) T-cells after viral reactivation; in contrast, HIV-1 can evade CARD8-sensing when its protease remains inactive in infected cells prior to viral budding (By similarity).
What are the official names of this protein?
Gag-Pol polyprotein, Pr160Gag-Pol.
What are the subcellular locations of this protein?
[Gag-Pol polyprotein]: Host cell membrane; Lipid- anchor. Host endosome, host multivesicular body. Note=These locations are linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid- anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: OR3A1_HUMAN
Sequence: MQPESGANGTVIAEFILLGLLEAPGLQPVVFVLFLFAYLVTVRGNLSILAAVLVEPKLHTPMYFFLGNLSVLDVGCISVTVPSMLSRLLSRKRAVPCGACLTQLFFFHLFVGVDCFLLTAMAYDRFLAICRPLTYSTRMSQTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNVINHFYCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPMALIVISYIHVAAAVLRIRSVEGRKKAFSTCGSHLTVVAIFYGSGIFNYMRLGSTKLSDKDKAVGIFNTVINPMLNPIIYSFRNPDVQSAIWRMLTGRRSLA
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 3A1, Olfactory receptor 17-40, OR17-40, Olfactory receptor OR17-15.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DDL_RHOJR
Sequence: MSKPRTRVAVIFGGRSNEHSVSCVSAGSVLRNLDPERYEVVPIGITTEGSWVLGSTDPETLSIRGRALPSVDADGSALALTADPTRSGDLVALDDGEAGKILASVDVVFPVLHGAYGEDGTIQGLLELAGVPYVGPGVLASAAGMDKEFTKKLLAAEGLPIGFQVVLRPGTATLTDEQKSRLHLPVFVKPARGGSSIGITRVAEWAALDDAIAHARLHDPKVIVESGIIGREVECGVLEFPDGDVRASVIAEIRMPEGAGDDEAFYDFDSKYLDDVCEFDVPAKLDESVSDEIRELAVRAFSALDCQGLARVDFFVTEDGPVINEINTMPGFTSISMYPRMWGAVGVDYGTLVSTLVDTALARGIGLR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFK_AZOVI
Sequence: MSQQVDKIKASYPLFLDQDYKDMLAKKRDGFEEKYPQDKIDEVFQWTTTKEYQELNFQREALTVNPAKACQPLGAVLCALGFEKTMPYVHGSQGCVAYFRSYFNRHFREPVSCVSDSMTEDAAVFGGQQNMKDGLQNCKATYKPDMIAVSTTCMAEVIGDDLNAFINNSKKEGFIPDEFPVPFAHTPSFVGSHVTGWDNMFEGIARYFTLKSMDDKVVGSNKKINIVPGFETYLGNFRVIKRMLSEMGVGYSLLSDPEEVLDTPADGQFRMYAGGTTQEEMKDAPNALNTVLLQPWHLEKTKKFVEGTWKHEVPKLNIPMGLDWTDEFLMKVSEISGQPIPASLTKERGRLVDMMTDSHTWLHGKRFALWGDPDFVMGLVKFLLELGCEPVHILCHNGNKRWKKAVDAILAASPYGKNATVYIGKDLWHLRSLVFTDKPDFMIGNSYGKFIQRDTLHKGKEFEVPLIRIGFPIFDRHHLHRSTTLGYEGAMQILTTLVNSILERLDEETRGMQATDYNHDLVR
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein beta chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: UREE_PSE14
Sequence: MLVIHNRIEPQAEWAAELHLNFEARSKSRLRCFSAENEDVGLFLQRGQSPLRDGEFLKAEDGRVVRVCARPEKLMHVTCSSTFELTRAAYHLGNRHVALQVGDGWLRLLDDYVLKAMLDQLGATVETIEAPFQPEHGAYGGGHHHSRAGEEDFNYPPRMHQFGVRK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.