PharMolix/UniProtQA huggingface dataset:
Protein: KRBBA_RAT
Sequence: MDTAVVYADLHLARTGEPKREPPPSLSPDTCQCPRWHRLALKLGCACLILLVLSVIGLGVLVLTLLQKPLIQNSPADVQENRTKTTDSPAKLKCPKDWHSHQDKCFHVSQTSITWKGSLADCGGKGATLLLVQDQEELRFLRNLTKRISSSFWIGLSYTLSDEKWKWINGSTLNSDALNITGDTEKDSCASVSQDKVLSESCDSDNIWICQKELKRESTCNDS
What is the function of this protein?
Receptor for CLEC2D/OCIL.  Ligand-binding contributes to inhibition of cytotoxic natural killer (NK) cells.  May mediate MHC class I-independent 'missing-self' recognition of allografts, tumor cells and virus-infected cells.
What are the official names of this protein?
Killer cell lectin-like receptor subfamily B member 1B allele A, CD161 antigen-like family member B, Natural killer cell surface protein NKR-P1B allele RNK/SD/BN/F344.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: 1433_EIMTE
Sequence: MIEDIKTLREEHVYRAKLAEQAERYDEMAEAMKNLVENCLDQNNSPPGAKGDELTVEERNLLSVAYKNAVGARRASWRIISSVEQKEANRNHMANKALAASYRQKVENELNKICQEILTLLTDKLLPRTTDSESRVFYFKMKGDYYRYISEFSNEEGKKASAEQAEESYKRATDTAEAELPSTHPIRLGLALNYSVFYYEILNQPQKACEMAKLAFDDAITEFDSVSEDSYKDSTLIMQLLRDNLTLWTSDLQTQEQQQQPVGEGAEAPKVEATEQQ
What are the official names of this protein?
14-3-3 protein.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: MNMC_ECOUT
Sequence: MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLGGNHLEARFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEKFPLTRADLALAHQHWPELAPWAEQLQAQWPLPLPGCHRLLLDEGRITLDLWFGDINELTSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGSTLATFTSAGFVRRGLQEAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSTPWFNRTGSNKQEAAIIGGGIASALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDLLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVATNCSGITYPQGGWLCPAELTRNVLKLAQQQGLQIHYQYQLQDLSRKDDGWLLNFAGDQQATHSVVVLANGHQISRFSQTSSLPVYSVAGQVSHIPTTPELAELKQVLCYDGYLTPQNTANQHHCIGASYHRGSEETAYSDEDQQQNRQRLIDCFPHAQWAKEVDVSGKEARCGVRCATRDHLPMVGNVPDYDATLVEYASLAEKKDEAVSAPVYDDLFMFAALGSRGLCSAPLCAEILAAQMSEEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US10_EHV4
Sequence: MAHAIPRPAEEIPLVPGRARSVRLGSTLPRVMDCAYGSPMAVDGDVRTGGDCGGGEGLYPTSTDTAAHAVSLPRSVGEFASAVRAMSADAADALRRGAGPPPEIWPRAYRMFCELFGRYAVSPMPVFHSADPLRRAVGRYLVDLGAAPVETHAELSTRLLFCAHWCCLGHAFGCSRQAMYERECARFFEARLGIGETPPADSERYWVALLDMAGADPELFPRHAAAAAYLRTRGRKLPLPLPPQAGSATVSVASQSINF
What are the official names of this protein?
Virion protein US10 homolog, ORF3.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US10 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus matrix.
Protein: AMSH2_ARATH
Sequence: MVTLSSPSPSLSCVENVTCKSSHVSRVLISGTDNINHGESSEAKILRDVHISERLLEDFTELARENTEKDLETCGTLAAFLERGIFYVTTLIIPKQESTSNSCQAMNEVEVFSIQNERELYPVGWIHTHPSQGCFMSSVDLHTHYSYQVMVPEAFAIVVAPTDSSKSYGIFKLTDPGGMEVLRGCSETGFHPHKEPEDGNPVYEHCSNVYKNSNLRFEIFDLR
What is the function of this protein?
Zinc metalloprotease that cleaves 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
What are the official names of this protein?
AMSH-like ubiquitin thioesterase 2, Deubiquitinating enzyme AMSH2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67C family.
Protein: PYRG_SALPC
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TTLL1_BOVIN
Sequence: MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDESGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVTQSTKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVNNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGAERELRSRPGQSLGPKGSRLRDAGRTVLTTWK
What is the function of this protein?
Catalytic subunit of a polyglutamylase complex which modifies tubulin, generating side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin.  Probably involved in the side-chain elongation step of the polyglutamylation reaction rather than the initiation step.  Modifies both alpha- and beta-tubulins with a preference for the alpha-tail.  Unlike most polyglutamylases of the tubulin--tyrosine ligase family, only displays a catalytic activity when in complex with other proteins as it is most likely lacking domains important for autonomous activity.  Part of the neuronal tubulin polyglutamylase complex.  Mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility.  Involved in respiratory motile cilia function through the regulation of beating asymmetry.  Essential for sperm flagella biogenesis, motility and male fertility.  Involved in KLF4 glutamylation which impedes its ubiquitination, thereby leading to somatic cell reprogramming, pluripotency maintenance and embryogenesis.
What are the official names of this protein?
Polyglutamylase complex subunit TTLL1, Tubulin polyglutamylase TTLL1, Tubulin polyglutamylase complex subunit 3, PGs3, Tubulin--tyrosine ligase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the tubulin polyglutamylase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.
Protein: SYQ_SALHS
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGDIRYSSDYFDQLHAYAVELINKGLAYVDELTPEQIREYRGTLTAPGKNSPFRDRSVEENLALFEKMRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYPQGESEMVTMPNHPNKPEMGSREVPFSGEIWIDRADFREEANKQYKRLVMGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPIEIRLYDRLFSVPNPGAAEDFLSVINPESLVIKQGYGEPSLKAAVAGKAFQFEREGYFCLDSRYATADKLVFNRTVGLRDTWAKAGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_BORPD
Sequence: MSLSIGMVAGEPSGDLLASRVIAGLRRDETVQCQGIGGPAMQAAGFDAWHPMHALTVFGYVDALKRLPSLLRTYGDVKRRWLASPPSVFVGVDAPDFNLKLELALRQAGTPTVHFVGPSIWAWRYERIHKIREAVSHMLVLFPFEEELYRKEGIPVTYVGHPLADAIPMQPDRAAARQRLGLDADARVLAILPGSRSSEIRILAPRFLQAAQQLQRRDPGLVCVVPMVNAQRRAEFEAILAQYPVPGLRCLTAEDAASGGLPVAWSALEASNAVLVASGTATLEAALFKRPMVISYYLSPWMRRIMAWKSGQQRPYLPWVGLPNVLLRDFAVPELLQDDATPDKLAEATWAALTDDAQAARVEARFAAMHRDLTRDTATLAARAILEVAHGAA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: THIL_PARDE
Sequence: MTKAVIVSAARTPVGSFLGSFANLPAHELGAIVLKAVVERAGIDPSEVSETILGQVLTAAQGQNPARQAHIKVGLPRESAAWVINQVCGSGLRTVALAAQQVLLGDARIVVAGGQESMSLAPHAAYIAPGQKMGDMKMLDTMIKDGLWDAFNDYHMGTTAENVAGKWEISRAEQDQFAVASQNKAEAAQKAGKFADEIVPVTIKSRKGETVVDADEYIRHGATLEAMENVRPAFSKEGTVTAGNASGLNDGAAAVLVMTEDEAARRGLTPLARIASYATAGVDPQIMGTGPIPASRKALEKAGWSVGDLDLVEANEAFAAQAIAVNRDMGWDPSIVNVNGGAIAIGHPIGASGCRILNTLLFEMQRRDAKKGLATLCIGGGMGVALCLERP
What are the official names of this protein?
Acetyl-CoA acetyltransferase, Acetoacetyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHD_PROMH
Sequence: MSTVELLKHIYDINLSYLLLAQRLINQEKASAMFRLGISDSMADALKELTLPQLVKLAETNQLICNFRFEDSETIEQLTKESRVDDLQQIHTGILLSSNLFRQLSEHDTSATKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_SALPB
Sequence: MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARQGIVTPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: TRMB_CLOBB
Sequence: MRMRKKPWARPELESCNFFIVNPKENKGKWNESFNNENPIYLELGCGKGVFVAVHGSDNENINYIAIDIKDEVLGLAKRNIEKAYNEKNKELNNIKLMAQEIGLINEILDENDKISRIYINFCNPWPKKKHKKRRLTHTRQLIQYRNFLKENGEIWFKTDDDELFEESLEYFKEGKFRIEYITYDLHTSGFEGNIQTEHERMFTEQGIKTKFLIAIKED
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: VPS25_SCHPO
Sequence: MRVPSIYNFPPFFTRQLNDNTWHSQKAAWQMWILLWCRENRQTSITINPELLESSLLHNSTIHRTLPLSVFREIVEDMVKQNLAEWTEKRNPKDVFWVYWRSISEWGNMILKWLSDMGREGSICTFYELQEQYKEVDCLDEVLLHKVLELLMKKGNIELMKGSSGKYSGFKVLKA
What is the function of this protein?
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.
What are the official names of this protein?
Vacuolar protein-sorting-associated protein 25.
What is the protein family that this protein belongs to?
Belongs to the VPS25 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: DBF2_CANAL
Sequence: MTNFFNRSPKHQSHHYQPHQQDVTDISYSMENVSISSNAMMDIDTSYRSSKPTYNNPQQQQQQQQQQQAQNNLFNKENITPLNSPTKSILHNSPQQAKSSTSPQHLYNKLVNANYNGNSPQPGIQQQQNNRALQNNINQLQPPLNKRYKLTEAEFYAKANSARTKRLTSIAQLYFLDYYCDMFDYVINRRERTAIVEKNLLTDPMYKNDITKQQFEWKNYIGRERALLRKRRLKPKHKDFEMITQIGQGGYGQVFLSRKRDTREICALKILNKKLLIKLDETRHVLTERDILTNTRSDWLVKLLYAFQDQEKVFLAMEFVPGGDFRTLLNNTGYLIPPHARFYISEMFAAVNSLHELGFTHRDLKPENFLIDSKGHIKLTDFGLAAGTVCNDRIESMKIKLQNLQNLNDFNDDSNNDNHHYQVPSSLIYERQKIFKQSQQQQQQQNSNNTTANSIVGSPDYMALEVLEGKNYNYTIDYWSLGCMLFEALCGYPPFSGSKQDETYYNLKHWKTALRRPQTKDGRYVFSDRTWNLIIKLIASPNNRLQNFKQVQQQSYFSDIKDWGNLRQKTPPFTPQLDNEEDAGYFDDFEDDEMMMKYKDVFARQEQNEQLLEKSNTTTTTTTTTTTKNGKRFSPGSKFNDNFIGFTFKHKSNPNNKFTNGSGNTGRYGNGNGNNNNNGEINLLNMVENGNGIGNGNSRSSRLNPLATLY
What is the function of this protein?
Ser/Thr-protein kinase involved in the mitotic exit network (MEN) and required after the metaphase to anaphase cell cycle transition.  Required for proper nuclear segregation, mitotic spindle organization, actomyosin ring contraction, primary septum assembly, and normal hyphal morphogenesis.
What are the official names of this protein?
Cell cycle protein kinase DBF2, Dumbbell forming protein 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Cytoplasm, cytoskeleton, spindle. Nucleus. Bud neck. Note=In small unbudded G1 cells, localizes to the spindle pole body (SPB). At the G1/S transition, remains associated with the SPB but also starts to accumulate in a linear structure in the nuclei of the cells. During mitosis, a very faint signal along the mother-bud axis is observed, suggesting association with the mitotic spindle during this part of the cell cycle. Finally, localizes to the bud neck at the end of mitosis and cytokinesis.
Protein: VHUU_METKA
Sequence: MAEKRDVLNYLEMVIRSYDIULSCAAHVLDRVKFRIERKDED
What are the official names of this protein?
F420-non-reducing hydrogenase vhu subunit U.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
Protein: DEOB_BACAH
Sequence: MNKYKRIFLVVMDSVGIGEAPDAEQFGDLGSDTIGHIAEHMNGLHMPNMVKLGLGNIREMKGISKVEKPLGYYTKMQEKSTGKDTMTGHWEIMGLYIDTPFQVFPEGFPKELLDELEEKTGRKIIGNKPASGTEILDELGQEQMETGSLIVYTSADSVLQIAAHEEVVPLDELYKICKIARELTLDEKYMVGRVIARPFVGEPGNFTRTPNRHDYALKPFGRTVMNELKDSDYDVIAIGKISDIYDGEGVTESLRTKSNMDGMDKLVDTLNMDFTGLSFLNLVDFDALFGHRRDPQGYGEALQEYDARLPEVFEKLKEDDLLLITADHGNDPVHHGTDHTREYVPLLAYSPSMKEGGQELPLRQTFADIGATVAENFGVKMPEYGTSFLNELKK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH_HHV11
Sequence: MGNGLWFVGVIILGVAWGQVHDWTEQTDPWFLDGLGMDRMYWRDTNTGRLWLPNTPDPQKPPRGFLAPPDELNLTTASLPLLRWYEERFCFVLVTTAEFPRDPGQLLYIPKTYLLGRPPNASLPAPTTVEPTAQPPPSVAPLKGLLHNPAASVLLRSRAWVTFSAVPDPEALTFPRGDNVATASHPSGPRDTPPPRPPVGARRHPTTELDITHLHNASTTWLATRGLLRSPGRYVYFSPSASTWPVGIWTTGELVLGCDAALVRARYGREFMGLVISMHDSPPVEVMVVPAGQTLDRVGDPADENPPGALPGPPGGPRYRVFVLGSLTRADNGSALDALRRVGGYPEEGTNYAQFLSRAYAEFFSGDAGAEQGPRPPLFWRLTGLLATSGFAFVNAAHANGAVCLSDLLGFLAHSRALAGLAARGAAGCAADSVFFNVSVLDPTARLQLEARLQHLVAEILEREQSLALHALGYQLAFVLDSPSAYDAVAPSAAHLIDALYAEFLGGRVLTTPVVHRALFYASAVLRQPFLAGVPSAVQRERARRSLLIASALCTSDVAAATNADLRTALARADHQKTLFWLPDHFSPCAASLRFDLDESVFILDALAQATRSETPVEVLAQQTHGLASTLTRWAHYNALIRAFVPEASHRCGGQSANVEPRILVPITHNASYVVTHSPLPRGIGYKLTGVDVRRPLFLTYLTATCEGSTRDIESKRLVRTQNQRDLGLVGAVFMRYTPAGEVMSVLLVDTDNTQQQIAAGPTEGAPSVFSSDVPSTALLLFPNGTVIHLLAFDTQPVAAIAPGFLAASALGVVMITAALAGILKVLRTSVPFFWRRE
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: PYRDB_ENDTX
Sequence: MIPDLSVNFAGIKLKNPVLTASGTFGYGYELADLIPLKRLGGVVTKTVTLEPRAGNLQPRIAEVASGILNSIGLQNIGVRAFIEEPLEKLNKIGVPVIVSVAGVAVGEYVEIVKILSSQNGVSAIELNLSCPNLKKKIVCHDLPLMRDVIRGVKKVSRVPVIAKLSPLVTDISELALTAQNAGADGVTLTNTYPAMAVDIRTFKPKLSTVKGGMSGACIKPMSVRCVYDAYQDIKIPIIGCGGIMMGEDAVEFILAGATAVSVGSSSLVSPGNLIAIIDGIEDILKEKNIKSVKKIIGGINKVRNA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BFSP1_RAT
Sequence: MYRRSYVFQARQERYERAQPAGPTAQPGGTAPGLAALQALGERVAAQVQRARALQQRHAGLRRQLYAFQRLGEQPGPEEALARHVEANLQRARDLAAEHARLERQEAEAQRALDEFRSKYENECECQLVLKEMLERLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITILQQIIQTAPQVSLVTGGMREEKLLTEREVAALRNQLDEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDDEIQLYNGQIENLRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIEIEGNRLSSVFIETPISLITPSHGASLSLGSNVKDLTRAVQDITAAKPRQKALPKSLPKRKEIIAQDKVDETLEDAPLKTLQEPKAVQGELTGDGDSQLGAGGGHEVSPTQEGGPEDVPDGSQISKAFGKLCKVVKERVSGHKEPVPEPPADLFTKGRHILVTGESSFVDPEFYSSSIPARGGVVVSIEEDSMHHDGHVEPSPGQPMPPVENGQGVPQGREGAHSNHQQVTDKNGIRAKEPKDLEEKDDDSRKDDEAGRRPCPVIIPGPDGPSTTHSQTSGSNQGGPEGPGSKSSSLLAKSPSKALSFKKV
What is the function of this protein?
Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA (By similarity).  Involved in altering the calcium regulation of MIP water permeability (By similarity).
What are the official names of this protein?
Filensin, Beaded filament structural protein 1, Lens fiber cell beaded-filament structural protein CP 94, CP94.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Protein: RNPA_RIPO1
Sequence: MGLPKLNRLKSPREFQAVYQRGQRYQSDRLVLRVLWITDKTSNPAPTQFGIAISQKVSKKAVVRNRLKRQIKGAIRVLLPFIAPGAKIVISVRGNVSECQYEHFLRELKKLLIKAKIIYGHTREYFL
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CUTA_ECOSE
Sequence: MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_ECO8A
Sequence: MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_CHAGB
Sequence: MGGDKIKKDKRQKREDYRAAMRKDDISELPRKKFYRQRAHANPFSDHQLIYPPHPDQMDWSSLYPHYIVDEPTTTSPPPPPPVPEQTPSEPDLTPLRPKPLSKEVSVADIGCGFGGLLIALAPTMPEALILGLEIRVSVTHFVEDRIKALRAQNQAAGLYRNVGVLRANTMKFLPNFFRKAQLEKVFICFPDPHFKIRKHKQRIVSTTLNSEYAYVVKPGGIVYTITDVLDLHEWMVQHFDAHPSFERVSEEEQEADPCVAIMRTETEEGKKVERHKGEKHVALFRRLEDPAW
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCNT3_HUMAN
Sequence: MVQWKRLCQLHYLWALGCYMLLATVALKLSFRLKCDSDHLGLESRESQSQYCRNILYNFLKLPAKRSINCSGVTRGDQEAVLQAILNNLEVKKKREPFTDTHYLSLTRDCEHFKAERKFIQFPLSKEEVEFPIAYSMVIHEKIENFERLLRAVYAPQNIYCVHVDEKSPETFKEAVKAIISCFPNVFIASKLVRVVYASWSRVQADLNCMEDLLQSSVPWKYFLNTCGTDFPIKSNAEMVQALKMLNGRNSMESEVPPKHKETRWKYHFEVVRDTLHLTNKKKDPPPYNLTMFTGNAYIVASRDFVQHVLKNPKSQQLIEWVKDTYSPDEHLWATLQRARWMPGSVPNHPKYDISDMTSIARLVKWQGHEGDIDKGAPYAPCSGIHQRAICVYGAGDLNWMLQNHHLLANKFDPKVDDNALQCLEEYLRYKAIYGTEL
What is the function of this protein?
Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides.  Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis.  Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
What are the official names of this protein?
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3, C2GnT-mucin type, C2GnT-M, hC2GnT-M, Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase, C2/4GnT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.