PharMolix/UniProtQA huggingface dataset:
Protein: EBNA6_EBVB9
Sequence: MESFEGQGDSRQSPDNERGDNVQTTGEHDQDPGPGPPSSGASERLVPEESYSRDQQPWGQSRGDENRGWMQRIRRRRRRRAALSGHLLDTEDNVPPWLPPHDITPYTARNIRDAACRAVKQSHLQALSNLILDSGLDTQHILCFVMAARQRLQDIRRGPLVAEGGVGWRHWLLTSPSQSWPMGYRTATLRTLTPVPNRVGADSIMLTATFGCQNAARTLNTFSATVWTPPHAGPREQERYAREAEVRFLRGKWQRRYRRIYDLIELCGSLHHIWQNLLQTEENLLDFVRFMGVMSSCNNPAVNYWFHKTIGNFKPYYPWNAPPNENPYHARRGIKEHVIQNAFRKAQIQGLSMLATGGEPRGDATSETSSDEDTGRQGSDVELESSDDELPYIDPNMEPVQQRPVMFVSRVPAKKPRKLPWPTPKTHPVKRTNVKTSDRSDKAEAQSTPERPGPSEQSSVTVEPAHPTPVEMPMVILHQPPPVPKPVPVKPTPPPSRRRRGACVVYDDDVIEVIDVETTEDSSSVSQPNKPHRKHQDGFQRSGRRQKRAAPPTVSPSDTGPPAVGPPAAGPPAAGPPAAGPPAAGPPAAGPPAAGPRILAPLSAGPPAAGPHIVTPPSARPRIMAPPVVRMFMRERQLPQSTGRKPQCFWEMRAGREITQMQQEPSSHLQSATQPTTPRPSWAPSVCALSVMDAGKAQPIESSHLSSMSPTQPISHEEQPRYEDPDAPLDLSLHPDVAAQPAPQAPYQGYQEPPAPQAPYQGYQEPPPPQAPYQGYQEPPAHGLQSSSYPGYAGPWTPRSQHPCYRHPWAPWSQDPVHGHTQGPWDPRAPHLPPQWDGSAGHGQDQVSQFPHLQSETGPPRLQLSLVPLVSSSAPSWSSPQPRAPIRPIPTRFPPPPMPLQDSMAVGCDSSGTACPSMPFASDYSQGAFTPLDINATTPKRPRVEESSHGPARCSQATAEAQEILSDNSEISVFPKDAKQTDYDASTESELD
What is the function of this protein?
Plays an essential role for the activation and immortalization of human B-cells.  Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters.  Targets host chromatin through interactions with host transcription factors, especially RBPJ and IRF4 (PubMed:8627785, PubMed:26719268).  Alternatively, EBNA6 also regulates the transcription of the EBV oncogene LMP1 in a cell cycle-dependent manner.  Modulates the activity of several host proteins involved in cell cycle regulation including host cyclin A, MYC, RB, p21 and p27 mainly through binding to the host SCF(SKP2) complex (PubMed:16352731).  Inhibits the promoter of host H2AX and targets H2AX to proteasomal degradation in order to promote latency and cell proliferation (PubMed:24429368).  Upregulates host PIM1 expression and stabilization (PubMed:25121590).  Potentiates PIM1 to promote cell proliferation by inhibiting the growth suppressive properties of p21 (PubMed:25121590).
What are the official names of this protein?
Epstein-Barr nuclear antigen 6, EBNA-6, EBV nuclear antigen 6, Epstein-Barr nuclear antigen 3C, EBNA-3C, EBV nuclear antigen 3C, Epstein-Barr nuclear antigen 4B, EBNA-4B, EBV nuclear antigen 4B.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae EBNA-6 family.
What are the subcellular locations of this protein?
Host nucleus. Host nucleus matrix. Note=Associated with the nuclear matrix.
Protein: TRUB_LIGS1
Sequence: MDGILPLYKERGMTSNDAVIKCRKIFKTRKIGHSGTLDPEVDGVLPICVGKATKVVNYLMDSGKVYKGEITLGFATTTEDLEGEVISKVKLSEPFSDEKINEILSSFIGDIIQVPPIYSAIKVNGKKLYEYARAGEKVDIPERRVHIEYFKQIFPSKFDKEKGQQTIYFEVGCGKGTYVRTLAVDVGKKLGVPAVMSDLTRLKSGGFQIGMAKSLSQLEKLAHENKLSESLYPIDYAVKDLPRYDLKLEQWRIVKNGGFLSVNTFKEDYDRVNLFYDDRIRCIYQYNKEKNRYQSERMIDLS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RH31_ARATH
Sequence: MPLNFPLRIRFFAHSLSGTHLSYNTSSSVPLLFRIFSSGLNHFEFGSRINFSTRPNRDQPEFERRIRDGGEIRASKSLIEDEEELSNWVSGFRTGSSRGILKSDDEDEEDRSRGRNQEKRGIRNQVDSFRNKRYGGDRERGFNSRIQGKSSEASFRGRKETSFSRDREDEKGLRKREDLRLEDESSDEDVKSLVMGDIGDLLSEDDEEEDQDYDFLKKKAVSAFGFDKENVIEADKTRNANDSYLTKTRFDHYPLSPLSLKAIKDAGYETMTVVQEATLPIILKGKDVLAKAKTGTGKTVAFLLPSIEVVVKSPPTSPDNKRPPILALVICPTRELANQAATEANTLLKYHPSIGVQVVIGGTRLGLEQKRMQTNPCQILVATPGRLKDHIENTPGFATRLKGVKVLVLDEADHLLDMGFRKDIERIISAVPKERQTFLFSATVPEEVRQICLVALRRDHEFVNCVHEGTIETHQQVRQMHMIASLDRHFSLLYTLLREHIMGNVDYKVIVFCTTAMVTKLVADLLGELNLNVREIHSRKPQSYRTRVSNEFRKSKGLILVTSDVSARGVDYPDVTLVLQVGLPKDREQYIHRLGRTGRKGKEGEGILLLAPWEEYFLSSLKDLPITKSPLPSIDPETVKKVQKALCHVEMRNKEAAYQAWLGYYNSQKMIGRDKDRLVELANEFSRSMGLDNPPAIPKLILGKMGLKNVPGLRAK
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 31.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: RUVV_VARV
Sequence: METLTSSSQSLISSPMSKKDYSSEIICAFDIGAKNPARTVLEVKDNSVRVLDISKLDWSSDWERRIAKDLSQYEYTTVLLERQPRRSPYVKFIYFIKGFLYHTSATKVICVSPVMSGNSYRDRKKRSVEAFFDWMDIFGLRDSVPDRRKLDDVADSFNLAMRYVLDKWNTNYTHYNRCKSRNYIKKM
What is the function of this protein?
Plays a role in DNA replication by cleaving viral DNA concatamers to yield unit-length viral genomes.  The concatamer junctions contain inverted repeat sequences that can be extruded as cruciforms, yielding Holliday junctions that A22 protein cleaves.
What are the official names of this protein?
Resolvase OPG149.
What is the protein family that this protein belongs to?
Belongs to the RuvC family. Poxviruses-type subfamily.
Protein: CF089_HUMAN
Sequence: MDLAANEISIYDKLSETVDLVRQTGHQCGMSEKAIEKFIRQLLEKNEPQRPPPQYPLLIVVYKVLATLGLILLTAYFVIQPFSPLAPEPVLSGAHTWRSLIHHIRLMSLPIAKKYMSENKGVPLHGGDEDRPFPDFDPWWTNDCEQNESEPIPANCTGCAQKHLKVMLLEDAPRKFERLHPLVIKTGKPLLEEEIQHFLCQYPEATEGFSEGFFAKWWRCFPERWFPFPYPWRRPLNRSQMLRELFPVFTHLPFPKDASLNKCSFLHPEPVVGSKMHKMPDLFIIGSGEAMLQLIPPFQCRRHCQSVAMPIEPGDIGYVDTTHWKVYVIARGVQPLVICDGTAFSEL
What is the function of this protein?
Exhibits histone deacetylase (HDAC) enhancer properties (PubMed:23460338).  May play a role in cell cycle progression and wound repair of bronchial epithelial cells (PubMed:21857995).
What are the official names of this protein?
Bombesin receptor-activated protein C6orf89, Amfion.
What are the subcellular locations of this protein?
[Isoform 1]: Golgi apparatus membrane; Single-pass type II membrane protein. Midbody. SUBCELLULAR LOCATION: [Isoform 2]: Golgi apparatus membrane; Single-pass type II membrane protein. Midbody. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus, nucleolus. Note=Retained in nucleolar organiser regions (NORs) in mitotic cells (PubMed:23460338).
Protein: GCH4_AZOSB
Sequence: MNSPLAHAIPDVQNSEDSRQIAINKVGIKSIRHPVKVSDKNGGVQHTVANFNMYVGLPHNFKGTHMSRFIEILNSNEREISVESFEPMLREMVKRLEAETGHVEMTFPYFINKSAPVSGVQSLMDYEVTFTGEIHEGGRYEFTMKVVVPVTSLCPCSKKISAYGAHNQRSHVTVTATLNDHLWIEDVVQLVEGQASCEVYGLLKRPDEKYVTERAYDNPKFVEDMVRDVAGLLNKEVRIDAYAVESENFESIHNHSAYALIERDKRIEA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: 3NB_BOIDE
Sequence: MKTLLLAVAVVAFVCLGSADQLGLGRQQIDWGQGQAVGLPHGFCIQCNRKTWSNCSIGHRCLPYHMTCYTLYKPDENGEMKWAVKGCARMCPTAKSGERVKCCTGASCNSD
What is the function of this protein?
This bird-specific postsynaptic neurotoxin irreversibly binds and inhibits the chick muscle alpha-1-beta-1-gamma-delta (CHRNA1-CHRNB1-CHRNG-CHNRD) nicotinic acetylcholine receptor (nAChR) 100-fold more compared with the mouse receptor.  The weak binding to mouse receptor is reversible.
What are the official names of this protein?
Denmotoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Boigatoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOH_PECAS
Sequence: MSWLTPELIEILITVGKAVVILLVVVTCGAFMSMGERRLLGLFQGRYGPNRVGWGGSLQLVADMIKMFFKEDWVPNFTDKVIFTLAPMIAFTSMLIAFAIVPITPTWGVADLNIGILFFLMMAGLAVYAVLFAGWASNNKYSLLGAVRASAQTVSYEVFIGLSLMGVVAQAGSFNMRDIVDSQEHLWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTVSALMVTLFFGGWHGPFLPPFVWFALKTGFFMMMFILIRASLPRPRYDQVMAFGWKVCLPITLLNLLATAAVILYNA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CROS1_CROSA
Sequence: MGKCQAVFLLVGALCVLSLAGVANAAENHFKVQGMVYCDTCRIQFMTRVSTIMEGATVKLECRNITAGTQTFKAEAVTDKVGQYSIPVHGDFQDDICEIELVKSPNSECSEVSHDVYAKQSAKVSLTSNNGEASDIRSANALGFMRKEPLKECPEVLKELDLYDVKAN
What are the official names of this protein?
Pollen allergen Cro s 1.
What is the protein family that this protein belongs to?
Belongs to the Ole e I family.
What are the subcellular locations of this protein?
Secreted.
Protein: SP5G_CLOK5
Sequence: MQITDVRVRKIAAEGKMKAIVSVTFDNEFVVHDIKVIEGQNGLFIAMPSRKTPDGEFKDIAHPINTQTREKIQKAILGEYEKVKNEETVTEEKVEE
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: GBG2_HUMAN
Sequence: MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, G gamma-I.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: GCH1_STRA3
Sequence: MPNQEKMEKAIYQFLEALGENPDREGLKDTPKRVAKMYIEMFSGLNQDPKEQFTAVFSENHEEVVIVKDIPFYSMCEHHLVPFYGKAHIAYLPNDGRVTGLSKLARAFEVASKRPQLQERLTAQVAQALEDALAPKGIFVMIEAEHMCMTMRGIKKPGSKTITTVARGLYKDDRYERQEILSLIQKG
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: KDPA_GEOSE
Sequence: MSFRNIHYFLLLIVIAVPLGKYLYVAFFEKGKIDRFFSPIEAVIYRLSGIRSLEEMTWKSYCTALLIVNAALLGISYGLLRIQHYLPLNGAKVENMEPTLTFNTVVSFMTNTNLQ
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAHS_RAMVA
Sequence: MSRYLLRDVQAVLRGVRKVAESSLKLETEKVSLRLGDFRSQPSLRSVPASLTSRSQAFSLQEIAARAGVVLRGVQQQFRNVTGVNAAPVVAFDNGSVLYSERIHSQSSQKQAPTTVPTGSVSNSPQPEGKANEAAERAKQFMNPPVAPMDPVDKNEFVAMPEMGRSNGNGENKQAADFMKNQGDTDMDSQYAPDSSKNTKSVPTKEIVAEDGSMSIEDIKKATQVTPGVAVKNEGV
What is the function of this protein?
Mitochondrial heat soluble protein acting as a molecular shield in water-deficient condition.
What are the official names of this protein?
Mitochondrial-abundant heat soluble protein, MAHS.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KTNA1_DANRE
Sequence: MSLGEINENVKLAREYALLGNYSSAVVCYQGVLEQIKKYLYSVRDSSLQQKWQQVWQEINEETKQVREIMTTLESFQMESTPSKPSSFAQDNDIMPVHVEHRSSPCVVRKSSVPYKDSKGHGNRLSVGPRGQARPSPRVANGDKGKPQKSKEKKENPSKPKEDKNKAEAVETEVKRFDRGGEDKDLIDALERDIISQNPNVTWDDIADLEEAKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECRTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGTSENDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGRVDLLKINLKELDLANDVNMDKIAEQMEGYSGADITNVCRDASLMAMRRRIEGLTPEEIRNLPKDEMHMPTTMEDFETALKKVSKSVSAADLEKYEKWIAEFGSC
What is the function of this protein?
Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner.  Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A1, Katanin p60 subunit A1, p60 katanin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Predominantly cytoplasmic. Also localized to the interphase centrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules and interaction with katnb1.
Protein: JAL11_ARATH
Sequence: MALKVEAKGGKVGIQWDDGSDYHDVTKIYVRGGLEGIQFIKFEYVKAGKKVIGPIHGASGRGFTETFEINNLEKEYLLSIEGYYNASTGVIQCLQFITNKKTYDPIGYNEGARFTLSASRSKIIGFHGFADKYLNSLGAYFIKIPSIQSAIEGAKTTGKGFDDGGDYDGIRKVYVTTDGSAIRHVRFDYDKAGQVETRERGAKTGTQHEFTVNHPYEYITSVEGTYAHTQPYNCVVLTSLTFKTSKGRASPAIGKVTGSKFKLERQGDAIVGFHGRVGSCIDGIGVYYAPLPPSPPPPEKLQGQGGDGGDSWDDGAFKNVKKIYVGQGDVGIAAVKFEYETYTSEVILAERHGKETLLGYEEFELDYPSEYITAVEGCHDKVIGSETGVITMLRFKTNKRNSPPFGLESAFSFILEKDGHKIVGFHGKASTLLHQIGVHVTAIA
What are the official names of this protein?
Jacalin-related lectin 11.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: FYUA_YERPE
Sequence: MKMTRLYPLALGGLLLPAIANAQTSQQDESTLVVTASKQSSRSASANNVSSTVVSAPELSDAGVTASDKLPRVLPGLNIENSGNMLFSTISLRGVSSAQDFYNPAVTLYVDGVPQLSTNTIQALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDSTPRGYIEGGVSSRDSYRSKFNLSGPIQDGLLYGSVTLLRQVDDGDMINPATGSDDLGGTRASIGNVKLRLAPDDQPWEMGFAASRECTRATQDAYVGWNDIKGRKLSISDGSPDPYMRRCTDSQTLSGKYTTDDWVFNLISAWQQQHYSRTFPSGSLIVNMPQRWNQDVQELRAATLGDARTVDMVFGLYRQNTREKLNSAYDMPTMPYLSSTGYTTAETLAAYSDLTWHLTDRFDIGGGVRFSHDKSSTQYHGSMLGNPFGDQGKSNDDQVLGQLSAGYMLTDDWRVYTRVAQGYKPSGYNIVPTAGLDAKPFVAEKSINYELGTRYETADVTLQAATFYTHTKDMQLYSGPVRMQTLSNAGKADATGVELEAKWRFAPGWSWDINGNVIRSEFTNDSELYHGNRVPFVPRYGAGSSVNGVIDTRYGALMPRLAVNLVGPHYFDGDNQLRQGTYATLDSSLGWQATERMNISVYVDNLFDRRYRTYGYMNGSSAVAQVNMGRTVGINTRIDFF
What is the function of this protein?
Receptor for the bacteriocin pesticin and for the siderophore yersiniabactin.
What are the official names of this protein?
Pesticin receptor, IRPC.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: HSSS_STAAW
Sequence: MFKTLYARIAIYSITVILFSALISFVLTNVYYHYNLKASNDAKIMKTLKEARQYEQSAKPTHIQQYFKHLGQMNYQIMTVDQKGHKTFYGEPFREDTLSQNAINNVLNNKDYHGIKDKPFALFVTGFFDNVTDNTVGINFKTKDGSIAVFMRPDIGETFSEFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQTRKDEIGTLQYHFNKMRESLGQVDQMRQHFVQNVSHEIKTPLTHIHHLLSELQQTSDNTLRQQYINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQVDQLIKDIIRHEQFAADEKSLIILADLESINFLGNQRLLHQALSNLLINAIKYTDVGGAIDIALQHSHNNIIFTISNDGSPISPQAEARLFERFYKVSKHDNSNGLGLAITKSIIELHHGTIQFTQSNEYVTTFTITLPNNSL
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR.  HssR/HssS activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme sensor protein HssS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KRP5_ARATH
Sequence: MGKYIKKSKVAGAVSVKDKSHPPALGFRTRAAAAKNLALHRLRSHSDEADSFNYLQLRSRRLVKLPLLTNTRKQQKQQLIPSVNQCQTKNPRASSGPAKKLEPDTTTEEACGDNERISRSDCNFGDKGFDLESENRSMISDSKSIQSEIEDFFASAEQQQQRFFIQKYNFDIVSDNPLPGRYEWVKVMP
What is the function of this protein?
Inhibits CYCD2-1/CDKA-1 complex kinase activity without interaction with the complex.
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 5, Inhibitor/interactor of CDK protein 3, KIP-related protein 5.
What is the protein family that this protein belongs to?
Belongs to the CDI family. ICK/KRP subfamily.
Protein: RLR10_PLAVT
Sequence: MRVLNFVLTTTVVLLTSSEGIASSPQVRHIKPNVAIDHLSIRSLRATENPGSDESRLNEKDTGFDPDGSSSKEDEDIGEPTFWEKVRFRYWKTMGKTPGDLRKEYFEGMDEAVIKNNPNYKLVQQYEVYYDEKSSE
What is the function of this protein?
Effector that acts as a broad suppressor of cell death to interrupt plant immunity.  Inhibits cell death induced by cell death-inducing proteins, including the PAMP elicitor INF1 from P. infestans.
What are the official names of this protein?
Secreted RxLR effector protein 10.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: VP9D1_HUMAN
Sequence: MAAAAGDGTVKPLQSAMKLANGAIELDTGNRPREAYTEYLRSIHYISQVLLEEVETTKEAGETVPPDTSKMLKLAQQCLERAQSTAAKLGKTRLKPTMPAAAPIPQPAGRHRRVYSDEGGKLSPFLPPEIFQKLQGAESQSCKKELTPLEEASLQNQKLKAAYEARMARLDPSQAMQKTSLTLSLQRQMMENLVIAKAREETLQRKMEERRLRLQEAANRRFCSQVALTPEEREQRALYAAILEYEQDHDWPKHWKAKLKRNPGDLSLVTSLVSHLLSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGCCPPTPNPGSRRLRPSQSLHCMLSPPEPSAAPRPQDSPPTPPLQPGPVGSPSPLGDTASGLPDKDSSFEDLEQFLGTSERQGRGRGVQPEPQLQQLKTAVEEIHNAVDRLLSLTLLAFEGLNTAASKDRCLACIEEPFFSPLWPLLLALYRSVHRAREAALSRSMELYRNAPPTAIGIPTKLLPQNPEAKGATGYPYCAAAQELGLLVLESCPQKKLECIVRTLRIICVCAEDYCPTPEATPQAGPPPIAAAAIGADDLLPILSFVVLRSGLPQLVSECAALEEFIHEGYLIGEEGYCLTSLQSALSYVELLPRGGLAK
What are the official names of this protein?
VPS9 domain-containing protein 1, Protein ATP-BL.
Protein: MTNN_STAS1
Sequence: MIGIIGAMEEEVAILKDKIVNLEIINVAHVVFYKGRLHDKEVILTQSGIGKVNVAISTTLLINRFHPDLIINTGSAGALDKSLGVGDIIVSDMVAYHDADARAFGYQLGQIPQMPAQFVADSHLIELAKEAINDQKWVAKSGLIVSGDSFIGTAEQRADIKTNFPQAMAAEMEATAIAQTCYQFNLPFIITRAISDLADGDAGITFEAFLEKAAIASSQIVDRLIKTI
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: CYB_FRAFR
Sequence: MAPNIRKSHPLLKMINSSLIDLPAPSNISAWWNFGSLLAVCLTTQILTGLLLAMHYTADTSLAFSSVAYTCRNVQYGWLIRNLHANGASFFFICIFLHIGRGLYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIAGITIIHLTFLHESGSNNPLGISSDSDKIPFHPYYTLKDILGLTLMFIPLLTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILLLIPFLHKSKQRTMTFRPLSQTLFWLLVANLLILTWIGSQPVEHPFIIIGQMASLSYFTILLILFPLIGTLENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS6_NITEC
Sequence: MRHYEIIFIVHPDQSEQVSAMIERYSNMITERSGGIHRLEDWGRRQLTYPIQKLHKAHYILMNIECDQESLNELEHSFKFNDAILRHLVIRMNGPVTTPSPMMQDDKSKPDENSRGTAAPTVNVADDSASGAQVVAAEENDTQS
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TM40L_RAT
Sequence: MGNTLGLAPMGTLPRWSHRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSITHRLVLGGELVYHRRPGEEGAILTLAGKYSALHWVATLNVGSGGAHASYYHKANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITVG
What is the function of this protein?
Potential channel-forming protein implicated in import of protein precursors into mitochondria.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM40B, Protein TOMM40-like.
What is the protein family that this protein belongs to?
Belongs to the Tom40 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: MIC10_SCHPO
Sequence: MSTSQSSEQTLNYQWDVCLSNMVVQSGIGLGAGIVSSVLFFRRAAWPVWGGLGFGLGKSYADSNARLRTFHAIPKQLPASSTQKKD
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit mic10, Mitochondrial inner membrane organizing system protein PJ691.03.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=The C-terminus is located in the intermembrane space, while the location of the N- terminus is has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space (By similarity).
Protein: UCP3_PIG
Sequence: MVGLKPPEVPPTTAVKLLGAGTAACFADLLTFPLDTAKVRLQIQGENQAARSAQYRGVLGTILTMVRNEGPRSPYNGLVAGLQRQMSFASIRIGLYDSVKQLYTPKGSDHSSITTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHAGPRSNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCAEMVTYDVIKEKVLDYHLLTDNLPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYQNPLDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVSYEQLKRALMKVQMLRESPF
What is the function of this protein?
Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism.  Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis.  However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity.
What are the official names of this protein?
Putative mitochondrial transporter UCP3, Solute carrier family 25 member 9, Uncoupling protein 3, UCP 3.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.