PharMolix/UniProtQA huggingface dataset:
Protein: H3A12_CYRHA
Sequence: MKASMFLALAGLVLLFVVGYASGSEEKEFPRELLSKIFAVDDFKGEERGCKGFGDSCTPGKNECCPNYACSSKHKWCKVYLGK
What is the function of this protein?
Selective antagonist of neuronal tetrodotoxin (TTX)-sensitive voltage-gated sodium channels (IC(50)=1270 nM on Nav1. 1/SCN1A, 270 nM on Nav1. 2/SCN2A, 491 nM on Nav1. 3/SCN3A and 232 nM on Nav1. 7/SCN9A).  This toxin suppress Nav1. 7 current amplitude without significantly altering the activation, inactivation, and repriming kinetics.  Short extreme depolarizations partially activate the toxin-bound channel, indicating voltage-dependent inhibition of this toxin.  This toxin increases the deactivation of the Nav1. 7 current after extreme depolarizations.  The toxin-Nav1. 7 complex is gradually dissociated upon prolonged strong depolarizations in a voltage-dependent manner, and the unbound toxin rebinds to Nav1. 7 after a long repolarization.  Moreover, analysis of chimeric channels showed that the DIIS3-S4 linker is critical for toxin binding to Nav1. 7.  These data are consistent with this toxin interacting with Nav1. 7 site 4 and trapping the domain II voltage sensor in the closed state.
What are the official names of this protein?
Hainantoxin-III 12, HnTx-III.12, Hainantoxin-3.12, Mu-theraphotoxin-Hhn2a, Mu-TRTX-Hhn2a, Peptide F7-18.76.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 15 (Hntx-3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BCP1_ASPFU
Sequence: MGKRKELKDNDVEMGGTGRPVEDDESDEVMDIVNVDFEWFDPQPAVDFHGLKNLLRQLFDADSQIFDLSALTDLILAQPLLGSTVKVDGNESDPYAFLTVLNLQEHKDKPVIKDLTSYLQRKASSNPSLAPLSQLLSQSPIPPIGLILTERLINMPAEVVPPMYSMLLEEIAWAIEDKEPYNFSHYLIVSKTYEEVESKLDMEESRPQKKKKKSGSNVERFFFHPEDEVFERHAICSGSIEYTHKHDDGLSDSKRAFQDLGIKTSGSLILIDGPKLEAAVKDVTDYVKPPV
What is the function of this protein?
Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
What are the official names of this protein?
Protein bcp1.
What is the protein family that this protein belongs to?
Belongs to the BCP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DNE21_RHIME
Sequence: MSADAVFCELGARTNFSFLEGAAPAEEMVVFAKKAGLAGLGIADRNSVAGVVRAHAKAKVEGYPFQPGARLVFADGTPDILAYPKNRRGWGHLCRLLSAGNLRSKKGDCTLHLADLLEWQEELLLIVMQGEGRPEPESLEVLLGTLKEHAGNRLYLGLAPHYDGFDRHDFAVLAAIARKAGIGLLATNDALYHDPHYRPLADVVTSIREHVPIAGAGFLLQKNAERHLKGPREMARLFSDYPEAIANTRKFFRELAFSLDELSHQYPDENADGETPAESLRRLVAEGAAERYPEGVPEKVMRQIDYELELIHDKKYEPYFLTVHKLVKFARSVNILCQGRGSAANSSVCFCLGITDVDPQKFTLLFDRFLSKDRDEPPDIDVDFEHERREEVIQYIYRTYGKEHAGLTAAVISYRSRSAGREVAKAFGLSEDVQSALVSSIWGWGTSPFTEEQAKGAGLDAADPLTRRVLAYASLLMNFPRHLSQHVGGFVITRDRLDEVVPIMNTAMPDRYMIEWDKDDLDELKILKVDVLALGMLTCLAKGFKLLEAHYGEPITLAEIYQDHRDAVYDMICRADTVGVFQIESRAQMSMLPRLQPREMYDLVIEVAIVRPGPIQGNMVHPYLKRREAQRRGEAVVYPSPELKAVLERTLGVPLFQEQAMQIAITAAGFSPSEADRLRRAMATFKRTGTIHTFERKMVEGMVANDYEREFAERCFNQIKGFGEYGFPESHAASFASLVYASAWLKTYYPDIFCAALLNAQPMGFYAPAQLVRDAREHGVRMLPVDINHSDWDALLEGEGAFDKNAVHPRHASMREVIKTRKAVRLGFRLVKGLKQTDMKALVARRGEGYRSVHDLWLRSGLSRSVLERLADADAFRSIGLDRRAALWAVKALDEQSAVERLPLFEGAGSDDLQIEPKVALPDMPAGEQVIHDYRTLTLSLKAHPVSFMREDFSRRGILRSRDLAATATGRWVTVAGLVLVRQRPGSANGVIFMTIEDETGIANIIVWEKTFQKYRRQVMGSRLVKVRGRLQNQSGVIHVVADHLEDITPMLGLLRREARRFGVNDRADGALRPSADAREKKKLRQLRLGLPARAAPEGEAAAQVAEVMPKGRNFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase 1.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH601_ECOK1
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BORT9
Sequence: MRKILKLKVGREDLILETGLLAKQANGAVLATYGGSTVLATVCCSDSARENLDFVPLSVEYNEKYYAAGKIPGGFIKREGKPKDKEVLVSRLIDRPMRPLFDKRFGREIQVVPTTLSTDQMNPPDIVGMNAAFAAVFLSDIPFNGPIAAVRIAYLNSEFIVNPSFDEIQDSILDIVVAGSLDGITMVEGGANEVSEEVLLAAIDQAYEYIKQICNLQKEFILIVGEREKLPLAYEERVFEFKAELKDFIYSELKDACFVKGKLNRDKAIKLVKQKAYEHFSSVSQVDEENETLFYKALDDFEQEIVRRSILENNLRTDGRNPTQIRDIVAEVDLLRRTHGSALFTRGETQALAVTTLGTSIDEQIMDDIDGDKRLNFMLHYNFPPFSVGETGRLMTGRREIGHGHLAQRSLEAMLPKKDDFPYTIRVVSEILESNGSSSMATVCSGSMSLMAAGVPVKEQVAGIAMGLVSEGDKYVILSDILGEEDHLGDMDFKVAGTKNGITGFQMDIKISNVTKQLMKDALAQARIGRMHILSIMDSVISRSRDDISVNAPKIIQLQIDIDKISLVIGSTGKTVKAITDEFEVRVQIEQDGRITLFGTDSLKMQKAKARIESIVREPKIGEIYEGVVKKINSFGAFIELTPTKEGFLSNRPKSRDDRYGDMRHSRYGSGRHSRYGRDSRNTFAMRPPRLEEGQMVKVRISDIDKFGKIELELVRD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_EDWI9
Sequence: MANLNDWLNLEPLAEDQTRRAVKPPSLYSVILNNDDYTPMEFVIEVLQTFFAYDIERATQLMLTVHYKGKAVCGVFTAEVAETKVALINRYARDNEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: MAKR2_ARATH
Sequence: MEAFSLLNYWKNSGGAVTFLPHSSESSSSSLCRYSAGESIGTTTIVTSVTETEDEEADENDDEGPFFDLEFALPAEEEDTDGGVGREGDSDCTDGGCEFKFTLSSCSGGEDRVDPDSLDDVFFKETIVEEVEPPTSSEQQTCSVKAPAAQLSASILKTATKLRVFMLGMKKSKLIQAKSEANFGSEDLDKQTHPPPPLSLSPESQQKSTVTVNLKVEEVPIISLFSRENSSKNSSSSSSSSSSSSSSLKKQNGNESVVSDEKRFVMMQKYLKKVKPLYIRVSRRYGEKLRHSGQLTAPSSARSTAEKADSPVATKTNNKPGNNINIPAGLKVVRKHLGKSRSSSSTATTPSSTTATVTTQSESRRRDDSLLQQQDSIQSAILHCKRSFNSSRDKDPSVLPRSVSEPSSYEK
What are the official names of this protein?
Probable membrane-associated kinase regulator 2.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RBM12_HUMAN
Sequence: MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSSRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASVGTAPPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPINPDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMILNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDLNDRPIGSRKVKLVLG
What are the official names of this protein?
RNA-binding protein 12, RNA-binding motif protein 12, SH3/WW domain anchor protein in the nucleus, SWAN.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYE1_BEII9
Sequence: MPDEVVTRFAPSPTGFLHIGGARTALFNWLFARHAGGRMLLRIEDTDRERSTDAAIAAILDGLSWLGLHWDGDVIYQFQRVARHRDVALSLLEAGQAYYCYATPQELEEMREQARKEGRPPRYDGRWRDRAENDAPSGVKPVIRLKAPRDGETTLDDKVQGKVTWANKDLDDLVLLRSDGTPTYMLAVVVDDHDMGVTQIIRGDDHLTNAARQMQIYQALGWSVPIMAHIPLIHGADGAKLSKRHGALGVDAYRGMGYLPEALRNYLVRLGWSQGDKEFFSTEEMIEAFDLAHVGRSPARFDFAKLENMNGHYLRHADDRHLVDMLSTTLPFLPKGLELAPKFTDERKAQLLAAMPGLKERAKTLVELLDGANFLFAERPLELDAKAQALLDASSRAHIAALVPLFEAAPEWKASALEAIVRAYVAETGVKLGQVAQPLRAALTGRATSPGIFDVLEVLGRDEGLARLRDQAG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX1A_CHEPU
Sequence: MKFSLFFSVFFLAVLHACLSESEIDLEDEEHFMSSDSFLSEIQDESRGKTCIERNKECTNDRHGCCRGKIFKDKCTCVKNGKTEKCVCTQKKWAKIIESYIGDIPALPKPVDDKCVPKHADCSKRKDDCCKGGIFKYQCKCYDMYDDDGEKTDLCGCVSPVEHQAIEGALRIAKKLIGDRWGR
What is the function of this protein?
Spider venom toxin that exhibits cytolytic activity by forming an alpha-helix across the membrane (PubMed:20657014).  Lethal to insect larvae (PubMed:20657014, PubMed:24717175).  Causes instant paralysis and death in the larvae of the flesh fly (S. carnaria) at doses of 20 ug/g, at doses of less than 10 ug/g causes reversible paralysis (PubMed:20657014).  Has cytolytic activity against insect Sf9 cells (PubMed:20657014).  Causes stable and irreversible depolarization of fly muscle fibers, leading to contracture at higher toxin concentrations (PubMed:20657014).  Destabilizes membranes (PubMed:20657014).
What are the official names of this protein?
DELTA-miturgitoxin-Cp1a, DELTA-MGTX-Cp1a, Double-knot toxin, DkTx, Toxin CpTx1, Toxin CpTx1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. Double-CSTX subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Probably forms a transmembrane alpha-helix in the target cell membrane.
Protein: MTEF3_CHICK
Sequence: MAVWARQVARCGWLRAAGLLGLRSRSGAARACCGAAPLPALLSGHRLPPWRLRVSVDYAQPSRAKGEACAPRSSLPVAVKQEQAAPETVSDLSAAKLCEDWDDVPPSSALEEISEEEAVKIIADPLLPPQSSTLRDYVDHSETLTKLVHLGVDLSQVEKRQKAGQLLLTLDFEKDITKILLFLKDVGIEDNQLGPFLTKNPYILGEELEALETRVAYLKSKKFGNAEITQMVSRAPYLLLFSVERLDNRLGFFKNELGLSVKKTKDLVIRFPRLLTGKLEPVKENLQVCQVEFGFERNEVQQIAFKTPKILTASKKRLRQTFDYLHNIMGIPHNMLTRFPQVFNSKLLRIKERHMFLIFLGRAQYDPTKPSYISLDQLVSLPDEVFCTEIAKASMQDFEKFLKTI
What is the function of this protein?
Binds promoter DNA and regulates initiation of transcription.  Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes.  Required for normal mitochondrial function (By similarity).
What are the official names of this protein?
Transcription termination factor 3, mitochondrial, mTERF domain-containing protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mTERF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPE_CHRSD
Sequence: MASFQCDIVSAEKAIFSGSAEQLIAAGVSGDLGILRGHAPLLTELKPGPVRVMREGGEEEVYYVTGGFLEVQPDVVSVLADTATRAHDLDEAAAEEARQEALKAMGDKQSDLDYTRAAAELAEAVAQLRTIQQLREKGSRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y033_HIS1I
Sequence: MIEKGQEPKSRYMPIAFILEVYYTIFGPSIYCPECNTFWRGFYSQHMKYCHFCQTELQERKF
What are the official names of this protein?
Uncharacterized protein ORF33.
Protein: DIM1_MACFA
Sequence: MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELRKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQRELALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.  Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Probable dimethyladenosine transferase, DIM1 dimethyladenosine transferase 1 homolog, DIM1 dimethyladenosine transferase 1-like, Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, Probable 18S rRNA dimethylase, Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: ACR1_ACIAD
Sequence: MNKKLEALFRENVKGKVALITGASSGIGLTIAKRIAAAGAHVLLVARTQETLEEVKAAIEQQGGQASIFPCDLTDMNAIDQLSQQIMASVDHVDFLINNAGRSIRRAVHESFDRFHDFERTMQLNYFGAVRLVLNLLPHMIKRKNGQIINISSIGVLANATRFSAYVASKAALDAFSRCLSAEVLKHKISITSIYMPLVRTPMIAPTKIYKYVPTLSPEEAADLIVYAIVKRPKRIATHLGRLASITYAIAPDINNILMSIGFNLFPSSTAALGEQEKLNLLQRAYARLFPGEHW
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of long chain acyl-CoA (with chain lengths of 14 to 22 carbons) to the corresponding aldehyde.
What are the official names of this protein?
Fatty acyl-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PBGP9_SOLSJ
Sequence: MKTFVLHIFIFALVAFASASRDSAKKIGSQYDNYATCLTEHSLTEDDIFSIGEVSSGQHKTNHEETELHKNGCVMQCMLEKDGLMSGADYDEEKMREDYIKETGAQPGDQRIEALNACMHETKDMEDKCDKSLLLVACVLAAEAVLADSNEGA
What is the function of this protein?
Colony queen number, a major feature of social organization, is associated with worker genotype for Gp-9.  Colonies are headed by either a single reproductive queen (monogyne form) or multiple queens (polygyne form).  Differences in worker Gp-9 genotypes between social forms may cause differences in workers' abilities to recognize queens and regulate their numbers (By similarity).
What are the official names of this protein?
Pheromone-binding protein Gp-9, PBP, Putative odorant-binding protein Gp-9.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_SPICI
Sequence: MSGTNYRTLAIVGSQWGDEGKGKITDYFAQQADLIVRWAGGDNAGHTIVIKRNKYKLSIVPSGAFNKKSMNVIGMVVVVNLRKLSYGNWVIYKQHGFDLLKNLRISDRVHLIFPYHMKIDELQEEYRQKDSIGTTKKGIGPCYQDKAERIGIRLGDLFDEKGFLQKLENNLKFKNEVLQKFLIVKDLTKINLKRIFWHYFQQIKSLVTDTSILVDNAIHNHQKFYLKEAQGVMLDLDHGTYPFVTSSNPTASSIPVGVGIAPRYINNVLGIVKAYNTRVGTGPFPSEIFGEVETYIREAGHEYGTVSGRARWIGWFDGILMKHSRELVVILVWLIMLLDVLTTIKELKICVGYEYQGQQIDYVPSTIKEYEMCKPILITMPGWDEDISNVTTFEGLPHNAQQYLMKLEEIVGVPISLFSVGPDREQTILMNKEIF
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_CHLTR
Sequence: MSKKCALTGRKPRRGYSYAIRGISKKKKGIGLKVTGRTKRRFFPNMMTKRLWSTEENRFLKLKISAAALRLVDKLGLDQVVARAKSKGF
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: LAC2_ORYSJ
Sequence: MASAASSLPLLVSSLLLALFALGAHADVKRYQFDIVMSNVSRLCHEKAMVTVNGSYPGPTIYAREGDRVIVNVTNHVKHNMTIHWHGLKQRRNGWADGPAYVTQCPIGSGGSYVYDFNVTRQRGTLWWHAHIAWMRATVHGAIVILPAAGVPYPFPKPDDEAEIVLGEWWHADVETVERQGSMLGMAPNMSDAHTINGKPGPLVPFCSEKHTYALQVQSGKTYLLRIINAAVNDELFFSIAGHNMTVVEIDATYTKPFAASTVQLSPGQTMNVLVSADQSPGRYFMVAKPFNDVPIPADNKTATAILQYAGVPTSVVPALPQTMPATNSTGSVAAFHDKLRSLNSPRYPADVPLAVDRHLLYTIGLNIDPCETCLNRSRLAASLNNITFVMPRTALLQAHYYGQKGVFAADFPDRPPARFNYTGVPLTAGLGTSLGTRLSKIAYNATVELVLQDTNLLSVESHPFHLHGYNFFVVGRGVGNFDPAKDPAKYNLVDPPERNTVGVPAGGWTAIRFRADNPGVWFLHCHLEVHTSWGLKMAFLVEDGSGPDESVLPPPKDLPKC
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-2, Benzenediol:oxygen oxidoreductase 2, Diphenol oxidase 2, Urishiol oxidase 2.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: PPME1_YEAST
Sequence: MSDDLRRKIALSQFERAKNVLDATFQEAYEDDENDGDALGSLPSFNGQSNRNRKYTGKTGSTTDRISSKEKSSLPTWSDFFDNKELVSLPDRDLDVNTYYTLPTSLLSNTTSIPIFIFHHGAGSSGLSFANLAKELNTKLEGRCGCFAFDARGHAETKFKKADAPICFDRDSFIKDFVSLLNYWFKSKISQEPLQKVSVILIGHSLGGSICTFAYPKLSTELQKKILGITMLDIVEEAAIMALNKVEHFLQNTPNVFESINDAVDWHVQHALSRLRSSAEIAIPALFAPLKSGKVVRITNLKTFSPFWDTWFTDLSHSFVGLPVSKLLILAGNENLDKELIVGQMQGKYQLVVFQDSGHFIQEDSPIKTAITLIDFWKRNDSRNVVIKTNWGQHKTVQNT
What is the function of this protein?
Demethylates proteins that have been reversibly carboxymethylated.  Demethylates the phosphatase PP2A catalytic subunits PPH21 and PPH22.  Forms inactive complexes (PP2Ai) with phosphatase PP2A-like catalytic subunits.  Involved in the regulation of cell cycle progression at START.
What are the official names of this protein?
Protein phosphatase methylesterase 1, PME-1, Yms2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: TRUA_SPIKU
Sequence: MLYLLLSIEYDGYDYSGWVKQKNARTIQGELEKAFFGICHQKIWTLGASKTDAGVHACDQKVLVKLTFQPRHLAFFIKTVSQTLPPNINIKGYQFVAENFSVRTVKVKEYVYTINDQEYDLFNHRYELKVNAPLNVKKLHQISQIFVGTHDFAYFAGVKPTEDIATVHTINKIWVKRNKAKKIEIHFRGKIFIRYQIRMLTQNILACYAGKVSLTELQAQLNCPPKGTTTKYCAKPYGLCLKKIKYLYTVKLNYKKLIIL
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: DCUP_METCA
Sequence: MTHCFIRALLRQPVERTPVWMMRQAGRYLPEYREVRERAGSFMNLCTSPELACEVTLQPLERYRLDAAILFSDILTVPDAMGLGLEFVEGEGPRFRNPIRGAADIHRLGVPDPEAELAYVPAAVRLIKQRLGDRAPLIGFSGSPWTLATYMVEGGSSREFRKVKCLMYEEPALMHELLEKLADAVALYLNAQIAAGVDAVMVFDTWGGNLDTEHYLAFSLRYAERVRQQLRLTGRGRIPAIFFTKGGGQWLEAMADAGYDALGLDWTTDIGSARQRVGDRVALQGNLDPVALYARPEIIRGEVRKILERYGRGSGHVFNLGHGVTPDIKPEHVGAMIEAVHEFSPAFHRT
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_UREPA
Sequence: MKYKVMFFGTPEIAKIVLETLFNMHEVDLIAVVSQPDAHFDRKKNVIYSPVKQFCLDHNIKLFQPEKIKEIEEEIRILGPDIIITCAFGQFINQGIIDIPKYKIVNIHASLLPKLRGGAPIHYAILNGELKTGITLMHTIKKMDAGNILFQRSLEINDCTTTKSLTLELANLSALMIKEHFLELVKPNLVGIQQDENSVSFAYNIQKDQNIINFDQPAFFINRFVNAMYDKPIAIMQYNGVSIKVYQVKITNQKSCQKPGTIMIFKNQLFVSTQDFDIELLLIQLPNKKPLSPKVLLNGKNPFIN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RTCA_METTP
Sequence: MIEIDGSYGEGGGQIVRTSVALSTLTGIPVRIKNIRRNRPRPGLAAQHVRAIEALAQISRAETRGVHLGSEEIEFIPGRISAGSYDVDIGTAGSVTLLIQCLLPALTAAEGPVTVTVRGGTDVRWSPTVDYLEHVALPAMHLFGVTATFRCERRGYYPRGGGVVVLSTRPSRLRPARLELIEEGICGISHCGSLPEHVARRQADAALELLKEKGYDARIDIQTMSSSSPGSGITLWSGFRGSSALGERGVRAEDVGREAAKALIDELKSKASVDVHLADQLIPYIALAGGEYTTREISSHTRTNIWTAQRILRCRIDIDEGEVFRIHSTGSG
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EEPD1_HUMAN
Sequence: MGSTLGCHRSIPRDPSDLSHSRKFSAACNFSNILVNQERLNINTATEEELMTLPGVTRAVARSIVEYREYIGGFKKVEDLALVSGVGATKLEQVKFEICVSSKGSSAQHSPSSLRRDLLAEQQPHHLATAVPLTPRVNINTATPAQLMSVRGLSEKMALSIVDFRREHGPFRSVEDLVRMDGINAAFLDRIRHQVFAERSRPPSTHTNGGLTFTAKPHPSPTSLSLQSEDLDLPPGGPTQIISTRPSVEAFGGTRDGRPVLRLATWNLQGCSVEKANNPGVREVVCMTLLENSIKLLAVQELLDREALEKFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPVLAEFYTEKDWSKKDAPRNGSGVALERSEANIKHER
What are the official names of this protein?
Endonuclease/exonuclease/phosphatase family domain-containing protein 1.
Protein: LPXC_SALTY
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFRPYNGFTLDFTIDFNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDDAELPLAFKAPSTVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.