PharMolix/UniProtQA huggingface dataset:
Protein: LMBRL_HUMAN
Sequence: MEAPDYEVLSVREQLFHERIRECIISTLLFATLYILCHIFLTRFKKPAEFTTVDDEDATVNKIALELCTFTLAIALGAVLLLPFSIISNEVLLSLPRNYYIQWLNGSLIHGLWNLVFLFSNLSLIFLMPFAYFFTESEGFAGSRKGVLGRVYETVVMLMLLTLLVLGMVWVASAIVDKNKANRESLYDFWEYYLPYLYSCISFLGVLLLLVCTPLGLARMFSVTGKLLVKPRLLEDLEEQLYCSAFEEAALTRRICNPTSCWLPLDMELLHRQVLALQTQRVLLEKRRKASAWQRNLGYPLAMLCLLVLTGLSVLIVAIHILELLIDEAAMPRGMQGTSLGQVSFSKLGSFGAVIQVVLIFYLMVSSVVGFYSSPLFRSLRPRWHDTAMTQIIGNCVCLLVLSSALPVFSRTLGLTRFDLLGDFGRFNWLGNFYIVFLYNAAFAGLTTLCLVKTFTAAVRAELIRAFGLDRLPLPVSGFPQASRKTQHQ
What is the function of this protein?
Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway (By similarity).  In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, promotes the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 (By similarity).  LMBR1L stabilizes the beta-catenin destruction complex that is required for regulating CTNNB1 levels (By similarity).  Acts as a LCN1 receptor and can mediate its endocytosis (PubMed:11287427, PubMed:12591932, PubMed:23964685).
What are the official names of this protein?
Protein LMBR1L, Limb region 1 protein homolog-like, Lipocalin-1-interacting membrane receptor, LIMR.
What is the protein family that this protein belongs to?
Belongs to the LIMR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS13_STRPB
Sequence: MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIRVKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNTKNNARTRKGKAVAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SELA_DESPS
Sequence: MPKNNLLRTLPKVDESIAQLRSTGVAYSSDFVLKKSVQTCIARERQGILAGKITEKRAEDSWHACFLKELKERQAPNLRRMINGTGVVIHTNLGRSLLSSQVAERLAQTASYYSNLEFDLATGKRGSRYSLVEDTICELTGAEAALVVNNNAAAVFLALDALCRGTEVIVSRGQLVEIGGSFRIPDVMARSGADLVEVGATNRTHLYDYEDAISEQTSMLLRVHTSNFRIIGFTSEVPAEEMVGLARKKNLLTMEDLGSGSLIDLTSYGFPKEPTVQELVKAGVDVVTFSGDKLLGGPQAGIIVGSKSVVERIKKSPMNRAFRVDKFTLAALEVVLRSYYDSRQALQEIPTLRMLTTGKDVLLKRARRISRRLSAKLKEKCTLRIVPTMSRVGGGAFPEHDLASWAVAFRPEHIRLSEIEKRLRKLNTPIIGRLENEKFLLDVRTIQDDEVGLLCSLLLEFFLEAS
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_SINFN
Sequence: MDLTVKTLEGKDAGKVSLSDAIFGLEPREDIIARVVRWQLAKRQQGTHKAKGRAEVARTGAKMYKQKGTGRARHHSARAPQFRGGGKAHGPVVRSHAHDLPKKVRALGLRHALSAKLKAEEIIVLDDLVANEAKTKALAGAFASLGLTNALIIGGAEIENNFKLAAQNIPNVDVLPVQGINVYDILRRGKLVLSKAAVEALEERFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: FRDD_ENT38
Sequence: MINPNPKRSDEPVFWGLFGAGGMWSAIVAPVIILLVAILLPLGLFPGEALGYERVLAFASSFIGRVFIFLMIVLPLWLGLHRIHHAMHDLKIHVPNGKWVFYGLATILTVVTLVAIVTI
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISCS_PSEPW
Sequence: MKLPIYLDYSATTPVDPRVAQKMADCLLVDGNFGNPASRSHVFGWKAEEAVENGRRQVAELINADPREIVWTSGATESDNLAIKGVAHFYQSKGKHIITSKIEHKAVLDTARQLEREGFEVTYLEPGEDGIVTPAQVEAVLRDDTILVSLMHVNNEVGSINDIAAIGELTRSRGVLFHVDAAQSAGKVEIDLQKLKVDLMSFSAHKAYGPKGIGALYVSRKPRVRLEAIIHGGGHERGMRSGTLPTHQIVGMGEAFAIAKQEMAAENQRIKALSDRFFKQVSDLEELYVNGSQTARVPHNLNLSFNYVEGESLLMSLKDIAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFSFGRFTTEEEVDYAAQKVCEAVNKLRELSPLWDMYKDGVDISKIEWAAH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTG_STAHJ
Sequence: MYTQGNPKLWTGRLDSETDPKQFRHFQTVKFANLENMENVSDKTGVGLLGYAVDKGVENNKGRIGSRKGPDIIKHEFAKLPDLSECEMLIDYGNVEHTSNHLRETQQEMARLSAKVIKQHKQAFLIGGGHDIAYAQYLATREVYSDASIGIINIDAHFDTRPDEPPTSGTMFREILDNDENVDYLVLGLAQGGNTRALYDYAKDNNIIYVYADELLHQVSPTIKDKIERFIHDHDTIMFTICMDVIDSAFAPGVSSPSVLGLYPHSVFEISKRVILSDKVSSISIAETNPDYDVDNRTSKLAANLIHHFLV
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: RS5_CAMC1
Sequence: MEKYNREEFEEVIVDIGRVTKVVKGGRRFRFTALVVVGNRNGLVGFGYGKAKEVPDAMRKAIDDAFKNIIHVKIKGTTIPHDVEVKYNASRMLLRPASEGTGVIAGGSARPIIELAGIKDILTKSLGSNNSANVVRATIKALSLLKS
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RPOZ_PROMT
Sequence: MNSNDLAKRGESLIRHSTNRYLTTVRIAFRAKQRRFDDFDGLLEESTVKPVQRAIIELSDEQDQPDLLPG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: COAA_RHOP2
Sequence: MDARSELHHYNPYRVFSRSEWANLRQDTPMTLDAGEVSTLRSLHDRLDLSEVEEIYLPMSRLLSIHVGAMQQLYYAQRRFLGVVERKMPYIIGVAGSVAVGKSTTARVLQALLARWSPRPKVDLITTDGFLHPNAVLERAGLMQKKGFPESYDLPALLAFLSDIKSGRRKVRAPIYSHLTYDIVPNKFAVVDRPDILIVEGVNVLQTGRLPRDGKAVPVVSDFFDFSVYIDADEPVLRDWYIRRFLALRDTAFHDPRSYFHRYAPLSDEEATATAIAIWERTNLANLEDNILPTRPRATLILKKGADHVVDSVALRRL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF1_RHIE6
Sequence: MEFHLDATFFAFVGLVLFLALVVYLKVPGMMARSLDDRADQIRNELAEAKRLREEAQHLLAEYQRKRKEAEAEAAHIVAAAEREAEMLTADAKKKTEEFVANRTALSEQKILQAEAEAMKAVRSAAVDLAIAAAETVLAKQADAKVQSELFGNAVSQVKTRLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HLDE_PHOLL
Sequence: MKMTLPDFHCAEVLVVGDVMLDRYWYGPTSRISPEAPVPVVKVNTIEERPGGAANVAMNIAALGANSHLIGLTGIDDAAHALSEKLRSVKVRCDFVSVPTHPTVTKLRVLSRNQQLIRLDFEEGFDNVDAQPMFERIEQALPHIGALVLSDYAKGALSQVQEMIKLANAAKVPVLIDPKGNDFERYRGATLLTPNLSEFEAVVGHCKDDNELVEKGTRLVKGLDLQALLITRSEQGMSLLSVDQPPLHLPTQAQEVFDVTGAGDTVIGVLATAIAAGKPLNEACFLANAAAGVVVGKLGTSTVSPIELENAIRGRAETGFGVMTEFQLKQAVVDARQRGERVVMTNGCFDILHAGHVSYLENARRLGDRLIVAVNSDASTKRLKGESRPVNPLEQRMIVLSALGAVDWVVPFEEDTPQRLIADVLPDVLVKGGDYKPEEIAGSEEVWAAGGDVKVLNFEDGISTTNIIKAIKNQ
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RPOB_PSEA6
Sequence: MVYSYSEKKRIRKDFGKRPQVLEIPYLLSIQLDSFKKFIDLDVDGQHGLEAAFRSVFPIKSYSGNAELQYVSYRLGEPVFDVKECQIRGVTFSAPLRVKLRLVLFDREAAPGTVKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDKGKTHSSGKVLYNARVIPYRGSWLDFEFDPKDNLYVRIDRRRKLPATIMLRALEIPTEEILGMFFEKNQVRIDGNRFMSDIVPDRLRGETAQFDILDSDGNVLVEAGRRISARHTRALEKAGIVELEVPAEYLVGRVFACDYVDQETGELVVAANDLLTLENVLALKEAGYTTFETLYINELDHGAYISDTLRIDSSTNRLEALVEIYRMMRPGEPPTKDAAETLFTNLFFSEDRYDLSSVGRMKFNRRLGRETSIGAGTLDKDDIVDVMKQLITIRDGKDDVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDAVMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTDKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLASFARTNDFGFLETPYRKIVDGVVTDEIDYLSAIEEGQFSIAQANVVLDETGRLADDLIPCRHRGETTLKESSEITYMDVSPQQIVSIAASIIPFLEHDDANRALMGANMQRQAVPTLIADKPLVGTGMEKTVAVDSGVTVVAKRGGRVDYVDASRIVIKVNEEETVAGEAGIDIYNLTKYTRSNQNTCINQRPTCNVGEPIVAGDVLADGPSTDLGELALGQNMRIAFMPWNGYNFEDSILISERVAMEDRFTTIHIQELSCVARDTKLGPEEISSDIPNVGESALGKLDESGVVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPNSVRGTVIDVQVFTRDGVEKDKRALEIEGMQLRQVKKDLSDEFNILADGIFARAKNLLIKSGIEESRLESAQREKWFDLTLTDEDAQTELDQIAEQFVEIKADFDKKFEIKRRKITQGDDLQPGVLKIVKVYLAVKRQIQPGDKMAGRHGNKGVISTIKPVEDMPYDVNGTPVDIVLNPLGVPSRMNIGQILETHLGMAAHGIGVKIDRMLKEHEEMAKLRSFLKEVYGAGTTHQEVDLDNFSDDEITRLADNLRKGVPMATPVFDGATEAEIKHMLTLADLPESGQIALFDGRTGREFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLLKEIRSLGINIELEEQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RIMP_RICM5
Sequence: MQTIEQQITNVIEESLTDMGFELVLVKVKGVNPKVVEILIDSLNGERISVEDCTKASRTISAILDVEDLIEAAYSLEVASSGLERPLVKFENYNRFLEREVKIKLKELLNGKTRYQGKIIKAENNKIYLKCEEQEVLIDYDLIKNANLVLTEEVFKKLLKQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_PROM5
Sequence: MSKFVFVTGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYLNVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTAMTRLNSVTTGSIYQAVINKERRGSYNGGTVQVIPHITGEIRERIHRVASNSNADIVITEIGGTVGDIESLPFLEAIREFKNDVNKNDVTYIHVTLLPYIKTSGEIKTKPTQHSVKELRSIGIQPDLLVCRSDKEINDSLKRKLSGFCGVNLNCVIEALDADSIYSVPLSLKKEGLCKETLRCLDLEDKECDLESWEKIIHNLRNPGNPIKVALVGKYIELGDAYLSVVEALRHACIEQKAFLDLHWVSAEMIEEKSAEEYLHDVDAIVVPGGFGNRGVNGKIASIKFAREKKIPFLGLCLGMQCAVIEWARNVVQLPGASSSELDPESENPVIHLLPEQEDIVDLGGTMRLGVYPCRLQKNTTGKELYNEDVIYERHRHRYEFNNFYKQIFVDSGYKISGTSPDGRLVELIELVNHPYFLACQYHPEFLSRPGKPHPLFKGLIKASREKLEQSK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ENO_BRUC2
Sequence: MTAIIDIVGREILDSRGNPTVEVDVVLEDGSFGRAAVPSGASTGAHEAVELRDGGSRYLGKGVEKAVEVVNGKIFDAIAGMDAESQLLIDQTLIDLDGSANKGNLGANAILGVSLAVAKAAAQASGLPLYRYVGGTNAHVLPVPMMNIINGGAHADNPIDFQEFMILPVGATSIREAVRYGSEVFHTLKKRLKDAGHNTNVGDEGGFAPNLKNAQAALDFIMESIEKAGFKPGEDIALGLDCAATEFFKDGNYVYEGERKTRDPKAQAKYLAKLASDYPIVTIEDGMAEDDWEGWKYLTDLIGNKCQLVGDDLFVTNSARLRDGIRLGVANSILVKVNQIGSLSETLDAVETAHKAGYTAVMSHRSGETEDSTIADLAVATNCGQIKTGSLARSDRTAKYNQLIRIEEELGKQARYAGRSALKLL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PSD_VIBVY
Sequence: MDKIKVGLQYWIPQHGLTRLVGKLASAKAGSLTTAIIRWFIKQYNVNMDEAKHADPKHYKTFNEFFVRELKEGARPIAEGDAIITHPADACVSQFGPITNGQLIQAKGHDFSAQELLGGDAALAEEFKDGSFATLYLSPRDYHRVHMPCDGTLRQMIYVPGDLFSVNPLTAENVPNLFARNERVVCIFDTEFGPMAQVLVGATIVGSIEQVWAGTITPPRGNTVYKWDYPASGNHAVILKKGEEMGRFKLGSTVINLFAKDAIRFDESMANGQPTVMGTPYAHQQ
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PFD5_ARATH
Sequence: MASSSSRGEMEKMGIDQLKALKEQADLEVNLLQDSLNNIRTATVRLDAAAAALNDLSLRPQGKKMLVPLTASLYVPGTLDEADKVLVDIGTGYFIEKTMDDGKDYCQRKINLLKSNFDQLFEVAAKKKSVADEAGMVLQAKVKQLTAATTS
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it (PubMed:19825635).  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (PubMed:19825635).  Together with other chaperonins, contribute to the regulation of gene expression by modulating the spliceosome function on pre-mRNA splicing post-transcriptionally by acting as a co-chaperone of Hsp90 to control levels of LSM8 (By similarity).  Required for the biogenesis of tubulins and for subsequent microtubules (MTs) organization and dynamicity (PubMed:19825635).  Necessary for tolerance to NaCl salt stress (PubMed:19825635).  Involved in the process leading to microtubules dissociation in response to gibberellic acid (GA) probably due to the DELLA proteins-mediated translocation of the prefoldin co-chaperone complex from the cytoplasm to the nucleus (PubMed:23583555).  Prevents cold acclimation (e. g.  7 days at 4 degrees Celsius) in a DELLA proteins-dependent manner by promoting nuclear proteasome-mediated HY5 degradation, thus modulating the expression of several genes and reducing anthocyanin biosynthesis, but seems not involved in constitutive freezing tolerance (PubMed:28412546).  Contributes to the GA-dependent regulation of PIN2 trafficking at the plasma membrane, thus influencing auxin flux (PubMed:29463731).
What are the official names of this protein?
Prefoldin subunit 5, Gene involved in microtubule biogenesis 5.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In the presence of gibberellic acid (GA) and at room temperature, the prefoldin complex stays in the cytoplasm and is functional (PubMed:23583555). But in the absence of GA or in response to cold, the prefoldin complex is localized to the nucleus in the presence of DELLA proteins, which severely compromises alpha/beta-tubulin heterodimer availability, thus affecting microtubules (MTs) organization (PubMed:23583555). This changing subcellular localization follows a daily rhythm coordinated oscillation (PubMed:23583555). Interacts with LSM8, a specific subunit of the LSM2- 8 complex, which is core components of the spliceosome (PubMed:32396196).
Protein: SOX7_HUMAN
Sequence: MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQVTPTGPTETSLISVLADATATYYNSYSVS
What is the function of this protein?
Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity).  May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity).  Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity).  Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation.  Binds the DNA sequence 5'-AACAAT-3'.
What are the official names of this protein?
Transcription factor SOX-7.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PSAA_OENEH
Sequence: MIIRSPEPEVKILVDRDPIKTSFEEWAKPGHFSRTIAKGPETTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQLWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYAEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGATAPGATTSTSLAWGGGDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIVQGRTVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: URE3_YERBE
Sequence: MQLTPREVEKLMIYTLSDVAFKRKARGLKLNYPEAVSIITVTAMEGARDGKSVEDVMKEASKVLTKDDVMDGVADLIPNVQVEAIFTDGSRLVTVHDPIK
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_SALPK
Sequence: MQEIQKNTKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHILPAYLEQLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIIRFAEAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVDGGDLAFDREEIPLQPAGWQPEEDDTSLEALRLDVIEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2332_IDILO
Sequence: MSVLLIAKTLGLFFITAIAEIIGCYLPYLWLKKDGSAWLLIPAAISLAVFAWLLTLHPAESGRVYAAYGGVYVVTALLWLKAVEGASLSTYDAVGAAFTLTGMAIIAVGWNH
What are the official names of this protein?
UPF0060 membrane protein IL2332.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GS30_BACSU
Sequence: MTVQEIKGKKLVKGIAPNVEPEALLNDKRKVFLFGSPSYTNIGDQAIAYAEEKFIKNHFPYYEYIEIMDYATDEGIELVKEIIREDDIVCFTGGGNLGNLYLDIEEDRRKVFSAFKDYKSISLPQSVYFEDTEEGQKEKKKTQDAYHQNTNLTIAARETQTLDVVKETFNSNVIFTPDMVLSLDIVPRELERDGVLFILRADKEKVTDEDFISQMKQWAEKTTYTERTDTVLDTVDTIDYADREKHFMEMLDRIGSSKLVITDRLHAMIFSIITKTPCLVFGNSYGKAKHSYRDWLESLNFIEYTDKNDVEELERMIDRLLQAEPNDVDLSKDFQPLIDFFAS
What are the official names of this protein?
General stress protein 30, GSP30.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide pyruvyl transferase family.
Protein: GUAA_RHIL3
Sequence: MTQTAHPDSVLIVDFGSQVTQLIARRVREAGVYCEIVPFQSAEEGFHRLQPKAVILSGSPASTVDEGSPRAPDIIFDSGLPVFGICYGQQTMCMQLGGKVESGHHREFGRAFLEVDRDCQLFEGLWSSGSRHQVWMSHGDRVTALPDGFEVVATSSNAPYAFIADEKRKYYGVQFHPEVVHTPDGAKLIGNFIHNIAGIKGDWSMSAYRQKAVEQIRAQVGDKRVICALSGGVDSSVAALLIHEAVGDQLTCILVDHGLMRKDEAAGVVAMFREHYNLHLLHVDAADRFIGELEGVSDPETKRKIIGRLFIETFEEEARKLGGADFLGQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRALGRELGLPDSFIGRHPFPGPGLAIRCPGGITREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RS12_PYRAE
Sequence: MPGKKSPYGLFAGGKLKRKRQKFRWNDVTYKRKMLGLVEKYDPLEGAPMARGIVLEKVGVEARKPNAAVRKCVRVQLVKNGKVVTAFVPLDGSLNYINEHDEVVIERIGGPEGRSLGDIPGVRFKVIKVNGVSLWAIWRGKKQKPTR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL7_AERS4
Sequence: MSITKDQIIEAVASMSVMEVVELIEAMEEKFGVSAAVAVAAGPAAEAVEEKTEFDVVLTAAGANKVAVIKAVRAATGLGLKEAKDLVEAAPANLKEAISKDEAETLKKQLEEAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.