PharMolix/UniProtQA huggingface dataset:
Protein: THI4_CITSI
Sequence: MAAMASTAFAPSVSSTTNKLFDSSFHGAPMSPSLLRLQPIKSSRPNNLSISASASPPYDLNTFKFDPIKESIVSREMTRRYMTDMITYADTDVVVVGAGSAGLSCAYELSKNPNIQIAIIEQSVSPGGGAWLGGQLFSAMVVRKPAHIFLDELGIDYDEQDNYVVIKHAALFTSTIMSKLLARPNVKLFNAVAAEDLIVKGGRVGGVVTNWALVSMNHDTQSCMDPNVMEAKVVVSSCGHDGPFGATGVKRLKSIGMIEEVPGMKALDMNSAEDAIVRLTREVVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAAHLALKSLGQPNALDGTYVGGVHPELILAAADSAETADA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, chloroplastic, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DNLI_PYRIL
Sequence: MQFGELVKTLAAVESTTQRTTMVKLLTSLFKKARPEEIDKIIYFVLGDLRPPWEGVELGVAEKLCLRAVSKATGVSISELEALYKKTGDVGEAARKALSTAKRPGLLAFGQQKPLEVSEVYDTLLKVAQASGEGAQDMKISLLASLFAKASPEEAKYIARFVVGKLRLGVADMTLIEALSDAFGVDKEALERAYHIYPDLGKLARHVAEGRPLEEIKITPGVPVLPMLAQRLSSSSEILAKLGGSAICEYKYDGERAQIHLKEGVVKIFSRRLEDITHAYPDVVKAVREAVSAREAILEGEIVAIDPDTGDMLPFQELMHRKRKHEVAVAVEMYPVVLNLFDLLYIDGEDLTNEPLIYRRVRLSEVVQETEKVSIAKWRVFDDAEEIDVFFHEAVSLGMEGLVCKSPTSVYEMGARGWNWIKYKRDYKSEMIDTVDLVVVGAFYGRGKRAGLYGAFLLAAYDPATDMFYTVCKVGSGFTDADLKKMYEMLQPYKIPHRHPRVVSKMEPDVWFTPQVVIEVIGAEITLSPLHTCCLGAVKPGVGLAIRFPRFTGRYRTDKSPEQATTVSEMIELYKRQKKVAQPE
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: JRA_DROME
Sequence: MKTPVSAAANLSIQNAGSSGATAIQIIPKTEPVGEEGPMSLDFQSPNLNTSTPNPNKRPGSLDLNSKSAKNKRIFAPLVINSPDLSSKTVNTPDLEKILLSNNLMQTPQPGKVFPTKAGPVTVEQLDFGRGFEEALHNLHTNSQAFPSANSAANSAANNTTAAAMTAVNNGISGGTFTYTNMTEGFSVIKDEPVNQASSPTVNPIDMEAQEKIKLERKRQRNRVAASKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGCTVPPNSTDQ
What is the function of this protein?
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' (PubMed:1696724, PubMed:2116361).  Plays a role in dorsal closure (PubMed:9224723).
What are the official names of this protein?
Transcription factor Jra, Jun-related antigen, Transcription factor AP-1 subunit Jra, dJRA, dJun.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Jun subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOA_CUSEX
Sequence: MVREKITVSTRTLQWKCVESRTDSKRLYYGRFILSPLRKGQADTIGIAMRRALLAEIEGTRITRVKFAKASHEYSTIAGIQESVHEIFMNLKEIVLRSNLYGTCDASISIKGPGHVTAKDIILPPHVEIVDSTQHIAWLTEPIDLCIGLKIERNRGYFIKTHPNFEDGSYPIDAVFMPVRNANHSIHSYGNEKQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHMEEENLHLEDADHTISLSPFTVYDKVAKLRKNKKKRSLESIFIDQLEFPPKIYNCLKKSNIFTLLDLLNNSQEDLIKIEHFRLEDVKQILGILGKHFALDLPKKKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid.
Protein: CU30_BOMMO
Sequence: MRVFLAICLSLTVALAAETGKYTPFQYNRVYSTVSPFVYKPGRYVADPGRYDPSRDNSGRYIPDNSGAYNGDRGDRGAAGGFYTGSGTAGGPGGAYVGTKEDLSKYLGDAYKGSSIVPLPVVKPTIPVPVTPTYVASKVVTPTYVASKVVPPSGAGYDYKYGIIRYDNDVAPEGYHYLYETENKILAEEAGKVENIGTENEGIKVKGFYEYVGPDGVTYRVDYTADENGFVADGAHIPK
What is the function of this protein?
Major cuticle protein of the integuments.  May interact with both chitin and epidermal cells to form stable cuticular structures.
What are the official names of this protein?
Larval cuticle protein LCP-30.
Protein: SUT22_ARATH
Sequence: MQLSSLSHTSITHKDKKKKMGIELQNHQSHHEEASPAEEPMSRWLINTPEPPSMWQELIGYIRTNVLAKKKHKRNKTKNSSSNLVYSCLKSAFPILSWGRQYKLNLFKKDLMAGLTLASLCIPQSIGYANLAGLDPEYGLYTSVVPPLIYSTMGTSRELAIGPVAVVSLLLSSMVRDLQDPVTDPIAYRKIVFTVTFFAGAFQAIFGLFRLGFLVDFLSHAALVGFMAGAAIVIGLQQLKGLFGLTHFTNKTDVVSVLSSVFHSLHHPWQPLNFVIGSSFLIFILLARFIGKRNNKLFWIPAMAPLISVVLATLIVYLSNAESRGVKIVKHIKPGFNQLSVNQLQFKSPHLGQIAKIGLISAIIALTEAIAVGRSFATIKGYRLDGNKEMMAMGFMNIAGSLSSCYVATGSFSRTAVNFSAGCETVVSNIVMAITVMISLEVLTRFLYFTPTAILASIILSALPGLIDVSGALHIWKLDKLDFLVLIAAFFGVLFASVEIGLLLAVGISFARIMLSSIRPSIEALGRLSKTDIFGDINQYPMANKTAGLLTLRISSPLLCFANANFIRDRILNSVQEIEGEENEQEVLKENGLQVVILDMSCVMGVDTSGVFALEELHQELASNDIRLVIASPRWRVLHKLKRAKLDEKIKTENIYMTVGEAVDIYVRARSTSHELC
What is the function of this protein?
Low-affinity H(+)/sulfate cotransporter that may be involved in the distribution of sulfate from vascular bundles to the palisade cells of the leaves.  Plays a central role in the regulation of sulfate assimilation.
What are the official names of this protein?
Sulfate transporter 2.2, AST56, AtH14.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YM9B_YEAST
Sequence: MITMKMFLFLNEACIFIDSVCEGIVFWGLCLFVCAECENASYRGAEVPYKTLFRSCDTSIFGVAECLNLVAIDPRSEAYC
What are the official names of this protein?
Putative UPF0377 protein YMR324C.
What is the protein family that this protein belongs to?
Belongs to the UPF0377 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AQY1_YEASX
Sequence: MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHRFKISRDTLRNHFIAAVGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAVSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANSLGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKRETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGPLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKVKPAVPLLWLKSNFPLLFFISRSLALNVIIFGKN
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes.  Involved in sporulation, freeze tolerance and osmotolerance.  Is non-functional in most laboratory strains.
What are the official names of this protein?
Aquaporin-1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RNC_AZOPC
Sequence: MFRNILNTIGAFFSKKKESYFALYRMLGFPPKNFSIYEKALLHKSSSKRDENGCYQNNERLEFLGDAIFNAIIAVILYKKFPTNDEGFLTNTRSKIVKRDTLDKIAYQLGINHLIMISAKVKNHKHIMGNTLEAFIGAIYLDKGYLKTKEFVEKRIINPYIDIDTLVREEVNFKSKLFEWCQKHKILLQFQTLENFTDNNRNVVFQIQALLNNHIAGIGIGYSKRESQQHASQMTWRKIRTDKIFLREVFAGVKKTNSEDK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_ORITB
Sequence: MSRRCTEVKRKSLPSNKYQSISAATPNQIMLASKLINKLTHHGNKELVEKMLDKIIQHIKHKYKADGFEVLESACNNVKPSLQVESLRIGGATYQVPSPVNELRSYTLAIKWIINSAANRTFEKSMWQKIAEELYEASNGRGGAVKKKDDNHKMAEANQAFSHLITKRRSRGN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PUR7_STAAR
Sequence: MTLLYEGKAKRIFSTNQENELRVEYKDEVTAGNGAKKDTMAGKGRLNNQITSIIFKYLQENGIESHFIKQLSETEQLVKPVKIIPLEVVVRNIASGSITKRLGFENGEVFREPLVEFFYKNDALNDPLITDDHIKLLNIATDKDIETLKTKALEINQVLKQLMHAMSLKLVDFKIEFGKTETGQILLADEISPDTCRIWDKATNANFDKDVYRNNTGSLIETYQIFLNKLEDLK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: DNAA_SHEWM
Sequence: MAVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVRDKYINIINQFFTEQMGSDAPKLRFDIGSRPSAPKPIQATAAVVKPKLESSPQKSQTSFNVNAPEPAATANHRSNINPTYQFENFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQVAMALSKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDTKEDYANLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLP_ACRMI
Sequence: DTTAGPDTTSAPQPTTPTGLCGFIRRQPLPEDNLNALNFTLSNFTVERWCAREPEFKQFLAQSVSDRCFGNGSCGVESGIPEVFIFPGFPVVNSPLLVRFYVRLQVNSSVSVVLERTVLTSILDRVLENLTAEFGVQFSVDGGFTEWSPFGPCSTSCGPGIQVRFRNCTNPPPINNGSDCVGPRNETRPCNNGSCPIDGNFTQWEIWSGCSVTCGKGVQRRFRSCTKPPPSNGGQDCIGDRLETRECLKPPCPVDGNFTEWGAWSKCSQTCENGTQVRFRSCTNPPPAFGGRDCMGPTNETRACNDGPCPGRLYPHGLLANDNLLPNRDAFSNFCGRINLFNQEIPFFIRRHRRVYICRNGMLKFRRSAIIRYPQRFPGPRNEDFLFRFRNSYIIAPYWLTISDDAFEQPINTSKVFYRIYSKFSRRDRDVLDRANHDVRRFQTSVPQFEAQWVLVVTWLQLYPPTFPGVRLSNSFQVVLITDGQHTFSLFNYPENGIQWSTPTGRLFPNLYPPGSGLPVAGYNAGDRNLPFFNLPNSGTVNIQNIDQMMGNTNLTGVWFFRLEMNSILSLAGKKCNEWSRQRTSRISPTLPPCPCLFGQATLDKRYFVDYNQTVSKRGNGTICAYSLPSGSRRWVQQCCYTDLPSGGKVLSSSPPESGGPYLIALPGSPVISDADGHEFCCSSSQCSLYYRLRPPRSCFGYTLRRRGLIFGDPHFTTLDNTTYTFNGLGEYTIVAIDDEAFEMQARTARTSGRGLGTAFSAAVAKERGTATVEARINQKAGDLEVLIAGKPFNISTITTTGTNIPDGNITLVRDSNGSITALFPSNIAFTFTDVEGTLAIAFEAPDDFKNRTKGLLGTWNDDPSDDFVTPDGTLVPADAAPRRIHYEFGLKWQINASQSLFTYSDLESPSTFVDLSYIPMFIDNITWVNDSFRYEAVKACGNNTQCLFDAAVTEDTSYGINTKKLEDNNNEINKELANFPPKILGPKVINATIGQAIEVKITAEHNSSDFFVFTVNNLPDVIILANTSRYLLIRWTPTSLQKVEPVFIVTDSHNSSSELRPLILLCPCANGSRCIDDEEVSNQRNKGFSFLLLSCTCPAGLTGQYCQHKIDACVENNQPCFPGVKCTDVSSSSNGTRYQCDPCPKGYSGNGSICEDIDECSDANVSKCDHSCINLPGSYVCDCNQGFSLEGDGTSCKDINECLISNDCMQNCTNLPGGRTCSCLDGFQIDPKDQTACVPISRCDTFKVGCQQVCVMDRGQPKCACHKGYSLNADGRTCDDINECTTHRHKCSQICHNLDGSYTCSCQPGFNLSPDQTTCEDIDECGLINEAHCEGSLEICINTMGSFRCECQDGFHRVNDTCQESLPSTNGPTGTTGIVASSVSIALTIKDADLHEWQARLSRMFMDAVAKVVVDYCKGNANGNCYGNAVIAKRYTRSISGTSLVARVHILNDFPETRDANLLVAFYVMLSTNQGEVYVMNKDSLLRALQESQTELSWAIKKEISEIRALKVDDESPTPYETREDGLEMIWLLVGVSVAVAVPLMIVIVILYREYRRIAKQRRKTNNFDLRQWSGARERTIYSGFTNSKSARL
What are the official names of this protein?
Mucin-like protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Note=Presence in the organic matrix of the skeleton may be due to shedding of a soluble peptide.
Protein: NINE_BPH19
Sequence: MRRQRRSITDIICENCKYLPTKRSRNKAKPIPKESDVKTFNYTAHLWDIRWLRHRARK
What are the official names of this protein?
Protein ninE.
What is the protein family that this protein belongs to?
Belongs to the ninE family.
Protein: RIMM_BORPD
Sequence: MPDAAHAAVPGDLVELGRINGAYGVKGWVKVQPHSAQADVLRKASSWWLTRLVPEKARGVVASAPQEYKVVQARPQGASVVAQLAGITDRDQAEALRGLAVQVSRSQFPAAADDEYYWVDLIGCAFYTNAEGEPARVGVVEEVFDNGAHAILRVVLQRAPAPGGEPEPRRDAKGRPLEMLVPFVGAHILAVDLSARRIDSNWPTEL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_BRUO2
Sequence: MSIIDTRTPEPKRFISGATGDWEVVIGMEVHAQVTSESKLFSGASTAFGAEPNSNVSLVDAAMPGMLPVINLECVRQAVRTGIGLNAQINLKSVFDRKNYFYPDLPQGYQISQFKQPIVGEGKIMISVGPDNKGQFEDVEIGIERLHLEQDAGKSMHDQHPTMSYVDLNRSGVALMEIVSKPDLRSSDEARAYLTKLRTIVRYLGTCDGNMDEGSMRADVNVSVHRPGGEFGTRCEIKNVNSIRFVGQAIEYEARRQIAILEDGGVIDQETRLFDPVKGETRSMRSKEEAHDYRYFPDPDLLPLEFNQAFVDALAAKLPELPDVKKQRLVETLGISVYDASILVTEKAIADYYEAVAEGRDGKAAANWVINDLLGALNKAGKDIEESPISPAQLGAIIDLIKEGTISGKIAKDLFEIVWNEGGDPKKLVEERGMKQVTDTGAIEKAVDDVIAANPDKVEQAKAKPTLAGWFVGQVMKAMGGKANPQAVNELVKSKLGIEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: AR11_XENLA
Sequence: MEGSSRDLVEKFVSKKLSQNEACRKFSNNPNPMPYLMEPSTSERPGEGATQGIVEEEVLQALLEATEEFELRYQRAFSDLTSQLHITQDTAQQSFQQVMGELFRDGTNWGRIVAFFSFGRALCVESANKEMTDLLPRIVQWMVNYLEHTLQPWMQENGGWEAFVGLYGKNAAAQSRESQERFGRLLTIVMLTGVFALVCYMRRR
What is the function of this protein?
Confers strong protection against cell death.
What are the official names of this protein?
Apoptosis regulator R11, XR11.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IL3_PANTR
Sequence: MSRLPVLLLLQLLVRPGLQAPMTQTTSLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIRIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF
What is the function of this protein?
This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
What are the official names of this protein?
Interleukin-3, IL-3, Hematopoietic growth factor, Mast cell growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor.
What is the protein family that this protein belongs to?
Belongs to the IL-3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PNP_HYPNA
Sequence: MFNKQSVSLEWAGRTLTIETGQVARQADGAVMVQYGDTIVLATAVFAKEAKPGQDFFPLTVNYQEKYFASGRIPGGFFKREGRPTEKETLTSRLIDRPIRPLFVDGFKHEVQVVVTTLSYDLENDADIIALVGASAALVLSGAPFMGPIGAARVGYKDGQYIINPTIAELEESELDLVVAGTTDAVMMVESQAAELSEDVMLGAVVAGHDAMQPVIDAIIALAEKAAKEPFAYEPPDHSAALKSVIDTVGADLSKAYKITAKGERYAAIGAAKDKAKAALLGTDEAPGVMTPEVFKTVFKEAEASVVRGDILKTGQRIDGRKLDQIRPIVAEAGFLPRTHGSSLFTRGETQAICVATLGTSDDEQYIDGLDGTKKEKFMLHYNFPPYSVGETGRMGGAGRREIGHGKLAWRALKAVLPKHEDFPYTIRMVSEITESNGSSSMATVCGCSLAMMDAGVPLTRPVSGIAMGLILEGSEFAVLSDILGDEDHLGDMDFKVAGTENGVTSLQMDIKVAGITKDIMGKALEQAKGGRMHILGEMGKALTASRGQLSENAPQMEIIKVPTDKIRDVIGSGGKVIRGIVDETGAKVNIDDDGTVQISAMDRKSIDAAIKMIKGITAEAEVGEIYEGKVVSMKDFGIFVNFFGPKDGLVHVSQMANKRIGHPKEMVKEGDKVWVKLMGFDERGKVRLSMKVVDQETGKELAEEAGDDASED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM2_CROSM
Sequence: AGEECDCGSPANPCCDAATCKLRPGAQCADGLCCDQCRFIKKGTVCRPARGDWNDDTCTGQSADCPRNPFH
What is the function of this protein?
Inhibits ADP- (IC(50)=56 nM) and collagen-induced (IC(50)=49 nM) aggregation of human platelets.  In vitro, inhibits adhesion of endothelial cells to vitronectin, type-I collagen and, to a lower degree, fibronectin and laminin.
What are the official names of this protein?
Disintegrin simusmin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YJNG_SCHPO
Sequence: MFQVIQKELDFGNAMIPKVWIQVIKLNPSSSIFVWGSNVSTCPAGDLALSMPGKSDVVTTKLTGAGSIDDLSTQMSRILSKKFQAQVYTSINLQGDFPNDPEVQSVFTQVIRAVIEIIESSKSS
What are the official names of this protein?
Uncharacterized protein C24B10.16c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYAY_ECODH
Sequence: MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGETVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: RS11_ERYLH
Sequence: MAREPGRVRRRERKNITSGVAHVNASFNNTMITITDAQGNAISWSSAGMMGFKGSRKSTPYAAQVAADDAGRKAAEHGVRTLEVEVKGPGSGRESALRALQAVGFTITSIRDVTPIPHNGVRPSKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SYY_LISMH
Sequence: MNIIDELEWRGAIYQQTDEEGLRKWVDEKQISLYCGIDPSGDSMHIGHLIPFMILRRFQNAGHRPIILVGGATGTIGDPSGKKEERKLQSMEQISKNVESLRVQLGKIFDFEGDSAASMVNNYDWTKDVSILDFLRDYGKEFNVNTMLSKDIVASRLEVGISFTEFAYQILQAMDFNHLYEFNDCRLQIGGSDQWGNITAGLDLIRKKQGENAKAFGLTIPLLTKADGTKFGKSEGGAIWLNPEKTTPYEFYQFWINTDDRDVVKYLKYFTFLTEAEIDELAKQVETEPHLRAAQKTLAAEMTKFVHSEEALEQALKISKALFSGDVKALTADEIEQGFKDVPTFVAEDSEANLVDWLVTLGIEPSKRQAREDVGNGAIYINGERQQDLEKIMDASDRIENKFTIVRRGKKKYFLVSYK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_CHLL2
Sequence: MNELKHMACVPCAEAGSPLAADEIDRLRQELPDWEVVTEEGMVRLRRTFTFPDFGQALAFTNRVGELAEAEGHHPRLVTEWGRVTVEWWTHSAGGLHRNDFIMAARTGGLHEG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: CLCA_SALTY
Sequence: MKTDTSTFLAQQIVRLRRRDQIRRLMQRDKTPLAILFMAAVVGTLTGLVGVAFEKAVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGCVGPVFNSLVLRTQDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGFNLIPIAAAGNFSVGLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQDAEQAEKNQNAPADENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBIG_PSEP1
Sequence: MSNVDRAEIAKFEALAHRWWDRESEFKPLHEINPLRVNWIDERVSLAGKKVLDVGCGGGILSEAMALRGATVTGIDMGEAPLAVAQLHQLESGVQVEYRQITAEALAEEMPEQFDVVTCLEMLEHVPDPSSVIRACYRMVKPGGQVFFSTINRNPKAYLLAIVGAEYILKMLPRGTHDFKKFIRPSELGAWSRDAGLQVKDIIGLTYNPLTKHYKLNSDVDVNYMIQTLREE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: EPB42_HUMAN
Sequence: MGQALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGRKQLLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQFEGDVIDLSLRLLSKDKQVEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMEREKDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTVVAPELSA
What is the function of this protein?
Probably plays an important role in the regulation of erythrocyte shape and mechanical properties.
What are the official names of this protein?
Protein 4.2, P4.2, Erythrocyte membrane protein band 4.2, Erythrocyte protein 4.2.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Cytoplasmic surface of erythrocyte membranes.
Protein: Y137_LACLS
Sequence: MSFTDETVRFEFGDSDKKEIGETLVDVYNVLEAKGYNPINQIVGYVLSGDPAYIPRHDDARNKIRRFDRDDIVEELIKNYLKDNGVNL
What are the official names of this protein?
UPF0297 protein LACR_0137.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.