PharMolix/UniProtQA huggingface dataset:
Protein: DCR1C_HUMAN
Sequence: MSSFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQIHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGTTMDKVVEILKPLCRSSQSTEPKYKPLGKLKRARTVHRDSEEEDDYLFDDPLPIPLRHKVPYPETFHPEVFSMTAVSEKQPEKLRQTPGCCRAECMQSSRFTNFVDCEESNSESEEEVGIPASLQGDLGSVLHLQKADGDVPQWEVFFKRNDEITDESLENFPSSTVAGGSQSPKLFSDSDGESTHISSQNSSQSTHITEQGSQGWDSQSDTVLLSSQERNSGDITSLDKADYRPTIKENIPASLMEQNVICPKDTYSDLKSRDKDVTIVPSTGEPTTLSSETHIPEEKSLLNLSTNADSQSSSDFEVPSTPEAELPKREHLQYLYEKLATGESIAVKKRKCSLLDT
What is the function of this protein?
Nuclease involved in DNA non-homologous end joining (NHEJ); required for double-strand break repair and V(D)J recombination (PubMed:11336668, PubMed:11955432, PubMed:12055248, PubMed:14744996, PubMed:15071507, PubMed:15574326, PubMed:15936993).  Required for V(D)J recombination, the process by which exons encoding the antigen-binding domains of immunoglobulins and T-cell receptor proteins are assembled from individual V, (D), and J gene segments (PubMed:11336668, PubMed:11955432, PubMed:14744996).  V(D)J recombination is initiated by the lymphoid specific RAG endonuclease complex, which generates site specific DNA double strand breaks (DSBs) (PubMed:11336668, PubMed:11955432, PubMed:14744996).  These DSBs present two types of DNA end structures: hairpin sealed coding ends and phosphorylated blunt signal ends (PubMed:11336668, PubMed:11955432, PubMed:14744996).  These ends are independently repaired by the non homologous end joining (NHEJ) pathway to form coding and signal joints respectively (PubMed:11336668, PubMed:11955432, PubMed:14744996).  This protein exhibits single-strand specific 5'-3' exonuclease activity in isolation and acquires endonucleolytic activity on 5' and 3' hairpins and overhangs when in a complex with PRKDC (PubMed:15071507, PubMed:15574326, PubMed:11955432, PubMed:15936993).  The latter activity is required specifically for the resolution of closed hairpins prior to the formation of the coding joint (PubMed:11955432).  Also required for the repair of complex DSBs induced by ionizing radiation, which require substantial end-processing prior to religation by NHEJ (PubMed:15456891, PubMed:15468306, PubMed:15574327, PubMed:15811628).
What are the official names of this protein?
Protein artemis, DNA cross-link repair 1C protein, Protein A-SCID, SNM1 homolog C, hSNM1C, SNM1-like protein.
What is the protein family that this protein belongs to?
Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YB39B_YEAST
Sequence: MGFFNNNPVIEFFHRITRKPSTIAMWVFAGLICSSTFYLMFMSSPTIDFNSKSKKKNDK
What are the official names of this protein?
Uncharacterized protein YBL039W-B.
Protein: NU5C_NEPOL
Sequence: MEIFHQAIWLIPVLPLSASMLSGIGLLTFRETTSDLRRLHGALAIGAMALSFVVSLGVLWNQLHGIAPVRWIIEWMLTDTFRLEIGYWVDPLTSTMLVVVTSVALLVMIYSDEYMHVDEGYVRFFVYLSIFTTSMLGLVLSPNLVQVYGFWELVGMCSYLLVGFWFTRPTAAEASQKAFITNRVGDFGLLLGILALYWMTGSFEFASIADRLGDLLIAIPSLRTIACIACILVFMGPIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMFPVFDQLPLVMELIAWTGTLTAFLGATMALTQSDIKKGLAYSTMSQLGYMIMALGTGAYSEALFHLTTHAYSKALLFLAAGSVIHGMEPVVGFSPMQNQNMHRMGGLRKYMPLTAMTFLLGTCSICGIPPLACFWSKDAILAEVFATHPTCWLIAWLTAGMTGFYMFRIYFLTFEGSFRSDLGRAKPKESHLGMVAPLIILAIPTVAIGSLGTPFAPVWETFVHAPGQLSSLDEEFDLAEFLEMAGSSVGIGLLGISLSSLMYRNYAIDATRISEYFSPLNRLFASKWYIDDLYAQVIVQGTRTIAQTLLIFDQRIIDGAVNLTAFGTLSAADTLKYWENGRVQFYILSIIFGVLFGSWLLTTHLSSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YOHO_ECOHS
Sequence: MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG
What are the official names of this protein?
UPF0387 membrane protein YohO.
What is the protein family that this protein belongs to?
Belongs to the UPF0387 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y1128_STRT2
Sequence: MPFVKIDLFEGRSEEQKIELAREVTEVVSRVAKAPKEAIHVFINDMPEGTYYPHGEMKKKN
What are the official names of this protein?
Probable tautomerase stu1128.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: YDDG_ECOLI
Sequence: MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATHHQAIEVGMVNYLWPSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMIFSTPVMIKLISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLATRRG
What is the function of this protein?
Amino acid transporter with broad substrate specificity (PubMed:17784858, PubMed:27281193).  Can transport various amino acids, including phenylalanine, tyrosine, tryptophan, L-threonine, L-methionine, L-lysine, L-glutamate, L-valine and L-isoleucine (PubMed:17784858, PubMed:27281193).  Overexpression confers resistance to phenylalanine and increases export of phenylalanine, tyrosine and tryptophan (PubMed:17784858).
What are the official names of this protein?
Aromatic amino acid exporter YddG.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Aromatic amino acid/paraquat exporter (ArAA/P-E) (TC 2.A.7.17) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRMA_EDWI9
Sequence: MPWIQIKINSTGGQAETLSDALMENGAVSVTFQDSHDNPVFEPLPGETLLWGDTDVIGLFDAETEMSAVIAELENHPALGAGFRHKIEQIEDKDWEREWMDNFHPMQFGHRLWICPSWREIPEPDAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLAGKTVIDFGCGSGILAIAALKLGAARAIGIDIDPQAIQASRDNAERNGVSGRLELYLPKDQPADLSADVVVANILAGPLRELAPLIGCLPRQGGLLGLSGILASQAESVCEAYREKFALDPVAEREEWCRITGVHR
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIG1_YEAST
Sequence: MGIPMQIYQDGKGVQFYHTRYQNVFDERASKYGNYTVNNDYPQLPDTIKEHIDQLTFSNVGEDGGDVGNYSEEDDDGDEEKELEDVFRSNRGLEFVRINNYFTTHDLQSFKSFRNFNSKYWIFYSNQAEDKKLLLYDFNGQHLIFIKQQFYGQLNLLLSDAIICMDCNFGYNSNTIQILVGFQNGKLLKLNCDLNGNVNNHLLLKDPSTSSHQSHLSILNVWAGLLPHFVVSFSLKDGLLITSLDHQQSNGSFQSFHTNIDLPVDLRTTTNVKSVLNFPQFTLYKGNDMIFHCKNLLGSDASTLNKEINFMLKIDEDVQKIDYLLKTNHILLETNMRYLSIPTRDPIENSNSSPPVSDSEVYPIFYKTQELHVHASGTGRQIANNGKYIFITEQHLYGTALSVYKYSISFKRWLFVGYSDIRAKYGIRSVKDLFVGNCPSVNSPVLTILTDDNNIQTILLK
What is the function of this protein?
Involved in the regulation of anaerobiotic glycerol metabolism.
What are the official names of this protein?
Protein YIG1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPF1_METCA
Sequence: MNINATLFGQMVTFALLVWFTMKYVWPPLLQALEERKKKIAEGLAAAEKGKHEMELAEKRATAALKEAKDQAAEIVNQAQKRANALVDESKEAAKIEGERILANARSEIDRELENAKEELRKQVSALAISAAEKILQREVDQKKHKEILAGLGKQLG
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CH60_SALA4
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKIADLKGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKSDAPDLGAAGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y058_OSHVF
Sequence: MDNIQSYKLAHIFDGSYGKLVYGIKKEFLFAHPELRYTIHYEKNDLFKYSSISKPIDRVISHKTLEKEDRVLIVLDAPITSSDIQIICVELWWKTGYIFIYKRNGMFSDPYRPEIKVETVITGVTNSAISTATEEPREFAEPPPPPATTARSSMQAFTELLERLSGNTAAPQDPTLSELTNLELVKKDEPEIKNKEDGILYGVELSTAIYRKPSDQSIILSPFWCNHKHWVYYSKQFTISAPTLPASKITEMDLEDICKRNFFLNQNKVMLMSLPEKKLSFQPKPQMRPLFIEEMMTQEHLNHLVYECSKTATWALNTLIPEYDIVERLDKVDKGVYNVLFYEKKVKPGRKYDMNTYPLMFYTKYGLRFDHINSSKKFKHIAFCVKREIVGVEVTYYDELMNKEWTELLYGEILPKVPIIQDFLENMERLHRQVVDGNITISAEMSLDIDNRIRRMLDDAVNDIPFHIYFTEDLERYIYHPFFPLPVMSPFAERFIDTDTDAETKRILRFVSEIRSKAENV
What are the official names of this protein?
Uncharacterized protein ORF58.
Protein: PUR5_BRUA1
Sequence: MTMENKPAGQNGLTYAQAGVDIDAGNLMVEKIKPLVRSTRRPGADGEIGGFGGLFDLKAAGFKDPVLVAANDGVGTKLKIAIDADIHDTVGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLSPDQGVAIVSGIAEGCRQAGCALIGGETAEMPGMYRDGDYDLAGFAVGAAERDRLLPRGDIAEGDIILGLASSGVHSNGFSLVRRIVELSGLGWKSQAPFQPGATLGEALLTPTRIYVKPLLAAIRACDGIKALAHITGGGFPDNIPRVLPKGLAAEIDLPAIAVPPVFSWLAKTGNVEPNEMLRTFNCGIGMIAVVNPAKVDEVIAALAAEGEKVVTLGRMTRREKDGVIYKGQLAL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRRT4_MOUSE
Sequence: MAGRSCLELGLFCWVLLAVPVGPQPASSVPGAPLTTLTPPPQSEASMLSLNLGLNFKFHLRGPAAVWGNPVTETHPLSPGLGQESEEEEEGDLRTDPLWELLVGSPGNYLPEWGSAEGSFTPWASSLPPESTSRLSGPTKRPTAHSQPRMGTVTWATALTATAPPTSAPRPHQSELELKFDVALRAGAAPTLGHRSLPLLPSLRASLAEIAGRLGPFGFFGTTVSPLRNFSRQSYPGTTAHPSFAFEVSDSPGLFGTTGSRPPPLLERKFSSPSLLDSVASPSSASVKTTPVQQDPTVSTSGPDELSPASFGNPSTQPGCEPGSCSEPELLDDLGQPPASPLPLFFLTLEADWAEARARWGLAWEAHVYGAGALFGLVALLALLALALLPWRCPPGAPCLALLDLLLLSAGTTRAFPLFYDAYGHRDRLPTLVWLLLQDLPLPCLAAGLGLACLLLARPRTPRCPAGLAALLLLGLGLAAAAALGSAVHRPLRPLRLASRGLHAFLAAFLSGLLLALSCWGGRRRRAGAPLGGAGFKGATPVPQVRSPFAPRESWRRAARTAPVAGTFGLLSGALQGYEVLHALGYGSQAGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPRRCWAKLFRLSPGHAAPLLPGGWVPGIPDKEPLGSAIARGDAELLQLCALAGPGPDLLLQGGGCRGFEGAGANPTQSTASSPSSDCTVDFRPPSPINLRRSIEEALCSEALLAPGLFQGPAFGEALPGLGLYRTISLGNKIGAGPSEKSENVPGSPAPPELPSPGAWPPGSSASSGSLCGLSRDSSSMLLCSSPDRPPRCPLVCVLSPPRPSESSPSLPASGSYQALSPPSRDSPEHASELQAEEALLQEQFLDACRQIDELSMGSDTIDL
What are the official names of this protein?
Proline-rich transmembrane protein 4.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DPOL_HBVH2
Sequence: MPLSYQHFRRLLLLDNEAGPLEEELPRLADEDLNHRVAEDLNLQLPNVSIPWTHKVGNFTGLYSSTVPVFNPDWLTPSFPDIHLHQDLIQKCEQFVRPLTKNEVRRLKLIMPARFYPKATKYFPLDKGIKPYYPENVVNHYFKTTHYLHTLWKARILYKRESTHSASFCGSPYSWEQELQHGSTSLNGEKGHGTESLCAQSSGILSRPPVGSTIQSKFQQSRLGLQHKQGQLANGKQGRSGRLWSRVHTPTRWPSGVEPSGTGHSDNLATRSTSRFHQSEVRKETNPSLSTSKGHTSTGHAVELNTVPPSTVGSESQGSVFSCWWLQFRNTEPCSDYCLSHIINLLEDWGPCYEHGEHHIRTPRTPSRVTGGVFLVDKNPHNTTESRLVVDFSQFSRGTTRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARVSSTSRIYNHQHGTLQNLHHSCSRNLYVSLLLLYQTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDLVLGAKSVQHLESLYTAVTNFLLSVGIHLNTAKTKWWGYSLHFMGYIIGSWGTLPQEHIVQKIKNCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACITAKQAFVFSPTYKAFLCKQYMNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGTFVAPLPIHTAELLAACFARSRSGADIIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLCRPLLRLPFRPTTGRTSLYADSPPVPFHQPARVHFGSPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: QUEF_RHOP5
Sequence: MSKPPRRSPRKPTPASPELQLGHEVVWPTSPDAARLDRVANPQRDTDYLARFTAPEFTSLCPVTGQPDFAHLVIDYAPGAWLLESKSLKLYLASFRSHGAFHEDCTVGIGKRIAAEIKPKWLRIGGYWYPRGGIPIDVFWQTGKLPKGLWVPDQGVRPYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_PSEAE
Sequence: MKDLLNLLKNQGQIEEFDAIRIGLASPEMIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVALAKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMTLRDIERVLYFESYVVIDPGMTTLEKGQLLNDEQYFEALEEFGDDFDARMGAEAVHELLNAIDLEHEIGRLREEIPQTNSETKIKKLSKRLKLMEAFQGSGNKPEWMVLTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIFGKLEGRGMATTIKAAKKMVERELPEVWDVLAEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVMGLYYMTREAINAKGEGMAFADLQEVDRAYRSGQASLHARVKVRINEKIKGEDGQLTANTRIVDTTVGRALLFQVVPAGLPFDVVNQSMKKKAISKLINHCYRVVGLKDTVIFADQLMYTGFAYSTISGVSIGVNDFVIPDEKARIINAATDEVKEIESQYASGLVTQGEKYNKVIDLWSKANDEVSKAMMANLSKEKVVDREGKEVDQESFNSMYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEIDCGTEHGLLMSPHIEGGDVVEPLGERVLGRVIARDVFKPGSDEVIVPAGTLIDEKWVDFLEVMSVDEVVVRSPITCETRHGICAMCYGRDLARGHRVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRTSAADNVQVKNGGTIRLHNLKHVVRADGALVAVSRSGELAVADDFGRERERYKLPYGAVISVKEGDKVDPGAIVAKWDPHTHPIVTEVDGTVAFVGMEEGITVKRQTDELTGLTNIEVMDPKDRPAAGKDIRPAVKLIDAAGKDLLLPGTDVPAQYFLPANALVNLTDGAKVSIGDVVARIPQETSKTRDITGGLPRVADLFEARRPKEPSILAEISGTISFGKETKGKRRLVITPNDGSDPYEELIPKWRHLNVFEGEQVNRGEVISDGPSNPHDILRLLGVSSLAKYIVNEIQDVYRLQGVKINDKHIETILRQMLRKVEVSESGDSSFIKGDQVELTQVLEENEQLGTEDKFPAKYERVLLGITKASLSTESFISAASFQETTRVLTEAAVTGKRDFLRGLKENVVVGRLIPAGTGLAYHSERKRQRDLGKPQRVSASEAEAALTEALNSSGN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PQQE_XANOR
Sequence: MTTAPPPLSVLLELTHRCPLACPYCSNPIALAALREEMDTAGWRSLLEQAAEMGVLQAHFSGGEPMLRKDLPELVAHARTLGLYSNLITSGVAGGEPMLDQLQAAGLEHVQLSVQDVDPAGADRIAGYRNSLPKKRDFAAAVRARGLPLTINAVLHRHNAERVPGMIALALEWQAERIEVAHTQYYGWGLRNRAALMPSREQLMATIDAVDTARRELGDSLAIDFVTPDYYARQPKPCMGGWGQRFVNISPRGDVLPCHAAETIEGMRFDNLRERALADIWNNGEAFVRFRGTAWMPEVCQGCPKREIDWGGCRCQALALSGNAATLDPVCERSPAHAQVRATAEREAAAPAPEFIYRRPERPAPATADTLE
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: PDAD_PICTO
Sequence: MQNLLPSKVFFTRGIGRGRTELQSFENALRSAGIAQFNIVSVSSILPPRAEIISKDDGLKLLNPGQILFTVLARNSSNELNRMISSAIGYAVPSDRDHWGYLSEHHAYGETENEAGYFAEELAARMLASTMGLEEELKWDDTRKEYVLENKILTTRNIASTTVVLKKDEWTTVVAAAVLIIM
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase, PvlArgDC.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: PRM4_YEAST
Sequence: MIADSSVLKKHTAIKRSTRIISLTLVLLGVFSFLLLTWNDSLEFYNSADPSENKKNSEEESEKKFVYKLPNLLKTADSFLSNENELNFQKVKEEISNIQSEVEVDIPEPSSKATSKFSSRSFQTDNVVTATTTTTLNPRSSSLALQKNCDHKKFDPRTDFLDIIRTSPAVLFIKSSQADSIFLKNLLQREFEISPELATVDLEKHSHGYELEKYIKQNKLNIDTSAALESIQSPYLFLNGISVINRGMVRDIIEPHSKGLLLPLLKSEARGNLLVEKKDIPSNS
What are the official names of this protein?
Pheromone-regulated membrane protein 4.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CLP1_DROME
Sequence: MSEDQGKDYTLESDSELRFEIEQKDAKVLVSLVSGFAELFGTELVKKKQYEFGVGAKVAIFTYQGCVLHVSGKMDVCYISKETPMVQYVNCHAALEQFRMEAEEKDRYGPVAMVVGPMDVGKSTLCRILLNYAVRVGRRPLYADLDVGQGSIAISGSVATILIERPANVEEGFAKTAPLVYHFGHKSPSGNSVLYNAVVSKMAEVTLQSLNSNKRTKSSGIIINTCGWVKGSGYAHLLHAAKAYGACAIFVLDQERLYNELLRDVPKGVHVVLLPKSGGVVERSKELRHEARDQRIKEYFYGNTRAPFYPFSFEVKFQDLRLYKIGAPPLPDSCMPIGMKAEDNKTKVVAVTPTPALIHHVLALSFAESVEDDVIGTNVAGFCCVTEVDMERQAVMLLSPQPRPLPPNALLLWSELQFMDNHT
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
Protein CLP1 homolog, Crowded by cid.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPG_BRUME
Sequence: MPSLKDLRNRIASVKATQKITKAMQMVAAAKLRRAQEAAEAARPYSQRMGAVLANIAQNVSGEDAPALMVGTGKDDVHLLVVCTAKRGLCGGFNSQIARLARDHARKLLAEGKTVKIITVGKKGADILRREFSALLHDHVDLREVKQLAFVHADQIGHKIIKLFEEGAFDVCTLFYSEFKSVISQVSTAQQLIPASADNEAEMETAGDAIYEYEPDPAAILSTLIPRNISVQIFRALLENVAGEMGAKMSAMDNATRNAGDMINKLSITYNRQRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS4_MESFL
Sequence: MSRYTGSTFKKARRYGFSILENGKEFSKGKKRVTTPGQHGKDKARLKMSGYGAQLQEKQKVKFMYGMTERQFRNTFAKAKKVHGGILGTNFLVLLESRLDNIVFRLGFAMTRQAARQLVNHGHILVNGKKLDIPSYQVKPGDSIEVKEAMKKNDKIAEALQNNESTVEFVKVDKANLKGQFVRLPERQELNLEINDALIVEWYNRLIK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DEOC_SHEHH
Sequence: MSDLKKAAQQAISLMDLTTLNDDDTDQKVIELCHKAKTPAGDTAAICIYPRFIPIARKTLNEIGGDDIKIATVTNFPHGNDDIAIAVLETRAAVAYGADEVDVVFPYRALMEGNETVGFELVKACKEACGEDTILKVIIESGVLADPALIRKASELSIDAGADFIKTSTGKVAVNATLEAAEIMMTVISEKNPKVGFKPAGGVKDAAAAAEFLGVAARLLGDDWATPATFRFGASSLLTNLLHTLELADAPQGAQGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC110_MOUSE
Sequence: MSPGYLPAPKAVLGSVPEKHLAEEDEVDSILLSASKILNSSEGVKESGGNEPEYGCASEPENQIQPQSALKVLQHQLESFQALRMQTLQNVSMVQSEISEILNKSIVEVETPQFNSEKSLVFSMHPEKDLPNETQEEIPSTKTLHSMGETFSSNSDTGLPQGTDIPPQIQVKDMLALQGLRTTADNSPPKKAMNTSEQPSATKSFSLYQFLPQGPQTAVPQAAPVILDKSTITTPFPKHGFCANLDDICHSIKHMKEELQKSHDKELALTSELHTFQADASTQGHHKHEPFPMHSSKLNFIQQENMEGNLSEDMKSKRISELEALVSKLLPLRDTVSKLHVNFCRKCKKLSKSEVYRGKKNEKNKDIPITSKNIMDLKFHSRAPRYTLSVLDLGKHKIKDKEGQAFIVSQGPATLENEKLPKGKFIPEQCVPKQSVAKIHYLQNYLKESLQNQKKMTELENENLALKTKMKPLVFTAQSLIQKVEAHEKQLKSLAEEKSALQSKLSKAEEENKDCLRELKKIVSTYNVLGGQHKMLEEKNSQLSLEKQQMLETIDHLKSKEHKSQSDMAVLQNENSRMNIEIEAMKTSMLLVQDEREMLEKETYQLLKDKSTLESDLKESKLEILQLKEKERLIKAEQESLLHSLDTAKAEKLSLEATLQESTSTRQKLERKLVDIQAYQSAAEEKFLKEIKSAKSETSIYKNNLAEISKECEILSKMVMEIKADNQILKEELKKHSQENTKFENSISRLTEDKILLENYVRSIENEKDTLEFEMRNLQRDYLSLSDKVSSQNNSASKSTYISRREKLYFDNYDAYEDASSLRNRPVASDLKGIPHKLYQRLPSKICK
What are the official names of this protein?
Coiled-coil domain-containing protein 110.
What are the subcellular locations of this protein?
Nucleus.
Protein: METF_BUCAI
Sequence: MKNYSQYHQDIMNQKLENIRNNIQCSFEFFPPKNSFLEENLWSTVNRLSLLKPKFFSVTYGANTGEREKTYDTVQKIYKKTGIITAAHLTCIDSTPHKLKEIAYNYWNSGIKSIVALRGDTLEKDYRHTMYAVDLVLLLKKIADFDISVAAYPELHPESKNVKSDILNLKKKVDAGASRAITQFFFNIESYLRFRDNCIKNKINIDIIPGILPVCNFQKLKRFSSMTNVKIPKWMLDMFNGLDDDIFTQKIIGSSIAIDMVKKLSCEGVKNFHFYTLNQSDITYSICHILGL
What is the function of this protein?
Catalyzes the NADH-dependent reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate.  Is required to provide the methyl group necessary for methionine synthetase to convert homocysteine to methionine; the methyl group is given by 5-methyltetrahydrofolate.
What are the official names of this protein?
5,10-methylenetetrahydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the methylenetetrahydrofolate reductase family.