PharMolix/UniProtQA huggingface dataset:
Protein: DGKH_DROSE
Sequence: MSHLKLDTLHVQRSPRGSRRSSRSSGRSSACSSGSISPVPIIPIISISHDGDESESESEIETEPARLFQRRMSIKCTNNLAAIIKEGFLLKHTWSFQRWRRRYFRLKRNMLFYAKDEKCDVFDDIDLSDLCYFECGIKNVNHSFQIITPTRSLVLCAESRREMEDWLGSLKTATAPQRPRGDSFLIEQHDILSNHHHWYATSHARPTYCNVCRDALSGVTSHGLSCEVCKCKVHKRCAAKSIANCKWTTLASVGKDIIEQADGSIIMPHQWMEGNLPVSSMCAVCKKTCGSVLRLQDWRCLWCRATVHVACRPQMAVACPIGPAKLSVVPPTSVHSISTDDAWDVASPKGNFSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLISTGPSLGLRLFRHFEMFRILVCSGDGSVGWVLSEIDRFNMHKQCQVAVMPLGTGNDLARVLGWGSSCDDDTHLPQILERYESASTKMLDRWSIMVFEKAIPVPKTPKMSISTEQEAMLTGMVTSANHHLRFIVETNDTQTLISSTRNLCDTVDDLVCRISEHHKDDEQLAVKCDILRQKLNMLLDALQEEEIGAHSGDDLIATIRSLIARSIPVTPGSNAYLLNPNISIEKTEKDQINSKERRNSRSLRSSEKEALQCRANSVKRAIYNVVEHSEPGRPKRYQRKLSITPFEALKLPTNASGESTPCTSPLPIIPPINIISPTMETSRLTCISPLPDTRRDSVDENFFNSINLPAPRQFADSRRSSGVPEVIQEIEEGANGETVYRRSRMSLTGGANIDDAGNRLSPCSDGGENTPTERKLDFLRVPIHTGEPIVDPLCDYRPHEVFERNYYMTREMDKDKEKDKEKDKPVEIDIEKDTCVEKEGSMPEEKLVHTCNLQVPGVVVTPNPQNVYSSASITIIDTDAQTTTEQSSSDDLGGEASDVLSAISNEECSVASEIFDKQDAGQTVGDIIQNMDASNFTHIDSPETSDETEAMPGESIMDDISSVLGHDITYALQDNTLTDDTTTLCSEHVGPPKPPRKKSLSALSRTQAHPRRRNSSPPRIARLARMDSDDNPQQFGFENIVFEIDNRCDDQKMREPPRYCSLAQFVEGNDIARQSFKQLMLEQHRGGDNDSEYPEHQQTPTNKGANLLITTSEDELSTQTAIKIEIQDIDATVRNLNSSMKPNTILTTSTSPTKKSGHGQDISVVVRPPTPLRGDSTKPTVSLLPVSSGGAMAVSMTCSGMLGVRAMNASEIRRHSSHAPGLAVREFDKDKDRRHSGFNPNQLTLDPEHARFLSSSPAASRRISCGSLFKKKNKQIATKRSYGLFSVRFFVVAEPDFRLATLALIRPLIPLNEALPNLQTLKGSKSSLFMGSTLFGFDHLASAEKDKEEKGGKDKEKTPTEETNRKLPIINPLVRLPNWPLANGGGFISKCLLANADTLCAAVSPLMDPDETLLAGYHEKCVMNNYFGIGIDAKISLDFHNKREEHPEKCRSRARNYMWYGVLGSKQLLQKTCKNLEQRVQLECDGQRIPLPELQGIVILNIPSFMGGTNFWGSSTKKDDIFLPPSFDDRVLEVVAVFGSVQMAASRLINLQHHRIAQCQSVQINILGDEEIPIQVDGEAWLQPPGMIRILHKNRVQMLCRNRSLELSLKSWQEKQRQHSISIQRDASSTASEHANSTDEVISERECYVLLNFIEAVSSLVKWVKFLIISHPALQHDLYEVACRASEALESIHPQGKLLEGPSLRTKLVEVIDSSRQLYDDACTLLRDRGHSLILREDLETKLSAALANMEMELKKCSVQKCIDGKLRAYFNVLAPNEESDGRRKSRPFWVRLRSGSTAGQQAFKPPLTNTREAPNNWSVNEVVTWLETMQLSEYVDSFLKNDIRGKELLTLGRRDLKDLGVVKVGHVKRILQAIKDLSEN
What is the function of this protein?
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).
What are the official names of this protein?
Diacylglycerol kinase eta, DAG kinase eta.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FICD_MOUSE
Sequence: MILMPMASVVAVAEPKWVSVWGRFLWMALLSMALGSLLALLLPLGVVEEHCLAVLRGFHLLRSKLDRAQPVVPKCTSLCTELSVSSRDAGLLTVKTTASPAGKLEAKAALNQALEMKRQGKRGKAHKLFLHALKMDPGFVDALNEFGIFSEEDKDIIQADYLYTRALTISPFHEKALVNRDRTLPLVEEIDQRYFSVIDSKVKKVMSIPKGSSALRRVMEETYYHHIYHTVAIEGNTLTLSEIRHILETRYAVPGKSLEEQNEVIGMHAAMKYINTTLVSRIGSVTMDDMLEIHRRVLGYVDPVEAGRFRRTQVLVGHHIPPHPRDVEKQMQEFTQWLNSEDAMNLHPVEFAALAHYKLVYIHPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSEYYHVLEVANEGDVRPFIRFIAKCTEVTLDTLLLATTEYSVALPEAQPNHSGFKETLPVRP
What is the function of this protein?
Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context (By similarity).  The side chain of Glu-231 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place (By similarity).  Acts as a key regulator of the ERN1/IRE1-mediated unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of HSPA5/BiP (By similarity).  In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of HSPA5/BiP at 'Thr-518', thereby inactivating it (By similarity).  In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from HSPA5/BiP at 'Thr-518', leading to restore HSPA5/BiP activity (By similarity).  Although it is able to AMPylate RhoA, Rac and Cdc42 Rho GTPases in vitro, Rho GTPases do not constitute physiological substrates (By similarity).
What are the official names of this protein?
Protein adenylyltransferase FICD, AMPylator FICD, De-AMPylase FICD, FIC domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the fic family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: TYSY_FRAP2
Sequence: MREYLNFLKYIKDNGTKKGDRTGTGTTSIFGYQMRFDLQQGFPLVTTKKIHIPSVVHELLWFLSGSTNVKYLNDNKVRIWNEWATEEGELGPIYGKQWRDFNGEGIDQIAEVIEMLKTNPNSRRILVSAWNPCVVPSEKISPQENVAKGNSALPPCHAMFQFYIADNKLSCMLTQRSADAFLGVPFNIASYSLLTHMIAQQCDLDVGEFIWSGGDCHIYNNHIEQVNEQLSREPLDLPTLKILRKPSSIFDYKYEDFEFQNYKHHPAIKAKISV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_OCEIH
Sequence: MKVNHAEIVISAVSKKQYPEDQLPEIALAGRSNVGKSSFINRLINRKNLARTSSKPGKTQTLNFYRINESFYFVDVPGYGYAKVSKKEREKWGRMMEEYFQTRDTLRAVVLVTDLRHDPTQDDIQMYDFIKYFDLPVIIIGTKLDKITKNKRQKHINRAKQVLEMDETDLFIPFSAEIGEGKDEAWSALSRYIKR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: KUP_XANC5
Sequence: MSHTPKSAGSSHAPANSQTALVIGAIGVVFGDIGTSPLYTLKEAFSPHYGLTPDHDTVLGILSLVFWALMLVVTLKYVTVIMRADNDGEGGIMALTALAQRTLPGGSRSMYVVGILGIFGASLFFGDGVITPAISVLSAVEGLEVAAPRLEPFVVPITLVVLGMLFLAQRFGTERVGKAFGPITLLWFFALGAIGVYNMARAPEVLHALNPWWGVRFFAQHNWHAVFVLGAVVLAVTGGEALYADMGHFGAKAIRRSWQFVVLPMLTLTYLGQGALMLRNPAAVSNPFYEAVPEWALYPMIVLATAATVIASQALITGAYSVASQAMQLGYIPRMHIRHTSHSTIGQIYVPAVNWCLLALVAVAVIGFGDSASLATAYGVSVTGTMLITTVLMIIYARANPRVPAPLLWLFALVFLAVDCAFFYANIIKFLDGAWFPLLLGLILFTLMRTWRRGRKLLHDEIRKDGIKLDTFLPGLMLAPPVRVPGTAVFLTADPMVVPHALMHNLKHNKVLHERNVFLTVETLQVPYAAAGKRLKIDAIGDEFYRVHVRFGFMETPDVPLALMRSCDQGGIYFDPMDTTYFASRETIVASANRGMPIWRDKLFALMHRNAAPATGFFRIPGNRLVELGAQVEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ODP2_MOUSE
Sequence: MWRVCARRARSAVPRDGFRARWAALKEGPGAPCGSPRIGPAAVRCGSGIPRYGVRSLCGWSSGSGTVPRNRLLRQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYTLDLAAAAAPQAAPAAAPAPAAAPAAPSASAPGSSYPTHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGAPLCIIVEKQEDIAAFADYRPTEVTSLKPQAAPPAPPPVAAVPPTPQPVAPTPSAAPAGPKGRVFVSPLAKKLAAEKGIDLTQVKGTGPEGRIIKKDIDSFVPSKAAPAAAAAMAPPGPRVAPAPAGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSVDVNMGEVLLVRKELNKMLEGKGKISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGLETIASDVVSLASKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLIPADNEKGFDVASVMSVTLSCDHRVVDGAVGAQWLAEFKKYLEKPITMLL
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2, PDC-E2, PDCE2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KYNU2_CHAGB
Sequence: MDTEYQSFVETLRAGQKPEFPAHAKTIEYARELDAHDKLSQLRSDFNIPTKGSLRKKALDGGVAGETKEPRVPNGVSSATKPNGTVNSDLKDDEASIYFVGNSLGAQPKCIRQYIDAHLETWASIGVNGHFTSFDNSPLASWQDMAAACAAQSVDLVGAKSANEIIYMNTLTVNLHLMMASFYRPTAKRHKIIAEWKPFPSDSYALASQLHWHGLAPATSLIEIHPPNPTGSSPPTLTLTTSHILATIDAHADSTALLLLPGIQYYTGQLFDMARITRHARARGIVVGWDLAHAVGNVELELHAWGVDFAVWCTYKYLNAGPGALGGVFVHGRHHSFHRGGGGSGGVGGGRGEGGDGDGGDGGDGDGMALGYRHRLAGWYGADKAVRFEMEKVFWPAEGAAGWQVSNPSVVDLACVRATLGMFERVGMRALRDKAVLLTGYLEWLLLGLLADGVGKGGDGEAAFRIITPGHPADRGSQLSLLLRGGLLEGVSKELADGGVVVDVRKPDVIRVAPVPMYCRFEDVWGFITVFNRALDRCA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase 2, Biosynthesis of nicotinic acid protein 5-2, L-kynurenine hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UTP25_CANGA
Sequence: MDKRGRKELRSIRRAKRTKIEPEADAGVESSGSVLEAGPAVEEKVQDDGEKEDDKEQVYNALLTILKSEHKEDKVKTHRDHDEEESEAEEEEQAEDQYNDAFADGESDDEDDDEDEQAQEQEEIESDDEEKDPFDTHFNGEEAAKHGEALGNALKDNKLRYKSIKLKVGSADEDQVQEDAIFSVPYIEGETPKIEDPKLKCSLSSYFLKKRLRIQNNLLDTESNALTDLQRKIVDPMMQYKDILYEYDTYGKDEDEYRDLYTLHVLNHVYKTRDKIIKNNQKLQDNPDSEFLDQGFTRPKVLIIAPTRDSAYQIVTKLIEKSGLDQVDKKGKFRDQFYDPSFPPSSKPKSFQHIFKGNTNDYFVLGVKFTRKAIKLYSNFYQSDIIVCSPLGLQMIVENTDKKKRQDDFLSSVEVTIIDQFHSIEYQNYTHLFTIFDHLNKIPQEQHDADFSRIRMWYINDQAKFFRQTMIFTKYISPVANSLLNIKCRNLEGRWKNHKIVSSEDSSVGTVGLKVRQIFQRFNVLGNSVADEPDYRFKFFTSVVISNITKSTGYDDGTLIYIPEYSDYVRVRNYMKEKTSILFGDINEYSEQRSLTSNRTLFNQGRLKVLLYTERLHHFRRYELKGVKNVVFYKPPSDPEFYKEVVRYIGKTVFLGDADLNISTVRCCYSKLDGLALEKIVGTKRTGVLTHGQNETYEFK
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RPOB_CLOPE
Sequence: MVHPVQVGKRTRMSFAKVKDVAEMPNLIEIQLDSYKWFLDAGLYEVFDDINPISNFTGNLVLEFVGYTLDMDNIKYSVEECKERDTTYAAPLKVAVRLQNKETGEIKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYNYNVDKTGKKLFSATVIPNRGAWLEYETDSNDVIYVRIDKTRKLPISILGRAMGFGSDQELLEYFGEEERFKATIEKDNTKTKEEALLEIYKRLRPGEPPTVDSAISLIDSLFFDAKRYDLSRVGRYKFNKKLAIGLRIANQIAAEDIVDKLTGEVLVAKGEKISRANAEEIQNRGINSVDVLVEDRVIRIIGNHFVDIHKCVDFDISDLNIRELVHYPTLREILDNYSDEETIKEEIKKNMTRLIPKHIIKDDIFATISYQIGLAYNIGYVDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEAITPQQLINIRPVAAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYAKVNEYGFIETPYRVVDKAEGRVTGEIRYFTADEEDQYLVAQANEPLDENGCFIDKKVTVRDKGEVLVVPSKDVDLMDVSPRQLVSVATAMIPFLENDDASRALMGSNMQRQAVPLLKPYAPIVGTGIEYKAAVDSGVLPKAKNAGEVVYVSANEVRVKRELDGGVDTYRLLKFKRSNQGTCINQRPIVAKGDWVLKGEVLADGPSTDLGEIALGKNIRMGFITWEGYNYEDAMLISEELVREDVFTSIHIEEYECEARDTKLGPEEITRDIPNVSEDALKDIDERGIIRIGAEVRSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGEAGIIVDVKVFTRENGDDLSPGVNELVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFLPDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASALGWHIATPVFDGATETDIEDCLEKAGYNRNGKTVLRDGRTGEEFDNEVTVGIMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRVKTYEAIVKGENIPEPGVPESFKVLIKELQALCLDVKVLNDNNQEVKFKELAEDDDEIEVLEVNMEGTEDSTTEEAKEEKGEAYIPAEEIDEEIDYENIDLLDFTSDLDIEDDFN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL39_SCHPO
Sequence: MPSHKSFRTKQKLAKAARQNRPIPQWIRLRTGNTVHYNMKRRHWRRTKLNI
What are the official names of this protein?
60S ribosomal protein L39, YL36.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: RS13_CYAP4
Sequence: MARIAGVDLPRDKRVEIGLTYIYGIGLTRSQHILAETGVNPDTRIRELTDADISALRTAVEAYQVEGDLRRLENMNIKRLQDIGCYRGRRHRMGLPVRGQRTRTNARTRRGGRRTVAGKKKAPAKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: YR773_MIMIV
Sequence: MQSNIELVITDEKVQTRIIADKNILSENFPYFKAMFMYTEGQADYVCLHTQNVQVAHDLIVSCGNTSYKFQDKTWDYIFDLYKCRNFFGLDFIPLVDNTVPPEYIDKLIDTMEIIGYDYSTIKYIAHNLPKDYALNKLSIELLKSIQQILSEFYFLVENRNGLSMFDGVSKMCLKLFEFDFYSVEQMSYCYLNQTNRLVILDTNNILKIFDVQTLNVVAISSGNCFCNSIIYLESKNCIVGINSGGFEIYDAINLKLIGKINGPKQFDYVETSLIGKSSDDKYIIFQQAVETDYGYHYQLMIALVETGEIIGPIYNDKKEFSCICSPTQNIIIYGNYNNFTLWSLDSRSVIAELRLNVDPFKFVFIGFSLDGCYIIFVDSNAIAYIWSIVTKQFIRSNSTISMRNHKNPTYACNSYRQFNKEKFGLNNISILPNNNLVSTKGNCISIWNIMCQEPIESFNLPIDSFMSKIQVITNKRDLANKIRNFINS
What are the official names of this protein?
Putative BTB/POZ domain-containing protein R773.
What is the protein family that this protein belongs to?
Belongs to the mimivirus BTB/WD family.
Protein: MUG20_SCHPO
Sequence: MSEIITSLQTELSNRHANMVSEAVLAFSEHHDSALHSYFLNARVKDVILESLRTTEEKLRALDKLQLDASKNLSNLLVEYNSINAELESVNSKISSISSQEYALEEFQALSQNFEKNLVQHRRNSQNKLKCAMEKLKMIETSTHKAILDNF
What is the function of this protein?
During meiotic DNA recombination, binds to and may help activate DNA double-strand break (DSB) hotspot sites.
What are the official names of this protein?
Linear element protein Mug20, Meiotically up-regulated gene 20 protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome. Note=Localizes to chromosomal double-strand break (DSB) hotspot sites during the meiotic cell cycle.
Protein: KUP_BURTA
Sequence: MTDTNHSSMRQHSLQSLAIAAIGVVFGDIGTSPLYSLKEAFSPAHGIPLTPSAILGVISLLFWAIILVVGIKYVLFVMRADNNGEGGVLALMALSLRPLNPKSRITGLMMALGIFGACMFYGDAVITPAISVMSAVEGLEVATPQLSHLVLPITIVILIALFWIQRHGTATVGKLFGPIMVIWFVTIAALGVYHIARAPMIVSAINPYYAFSFMSEHVLLAYVVLGSVVLVLTGAEALYADMGHFGAKPIRLAAYVLVMPSLVLNYFGQGALLLLDPKAIENPFFLLAPQWAALPLVVLSTVATVIASQAVISGAYSLTSQAIQLGYVPRMKILHTSELAIGQIYVPVVNWLLLFVILCIVIGFKSSDNLAAAYGIAVTATMVITTILAAVVMVKVWNWNKLLVAMIIGVFLVIDLGFFGANLLKVEQGGWLPLGIGALLFFLLMTWYKGRHIVKERTAADGIPLAPFLQGLLAHPPHRVSGTAIYLTGNDTLVPVSLLHNLKHNKVLHERTIFMTFVTRDIPYVKDDERVTVHDAGEGLYIVKAEYGFNETPDVKAVLEEVSCQRAMTFELMDTSFFLARETVVPTHLPGMSIWRERVFAWMHQNAAKPTDFFAIPANRVVELGTKIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLGX_SALSV
Sequence: MTQLAIGEATPHGATYDGHGVNFTLFSAHAERVELCVFDSRGNERRYDLPGRRGDVWHGYLAGARPGLRYGYRVHGPWQPAQGHRFNPAKLLLDPYARRVEGELKDHPLLHGGHDEPDYRDNAAVAPKSVIISDHYDWEDDAAPRTPWGKTVIYEAHVKGLTYLHPELPQEIRGTYKALGHPVMVAYFKQLGITALELLPVAQFASEPRLQRMGLTNYWGYNPMAMFALHPAWASSPETALDEFRDAVKALHRAGIEVILDIVLNHSAELDLDGPTFSLRGIDNRSYYWIRDDGDYHNWTGCGNTLNLSHPGVVEYACECLRYWVETCHVDGFRFDLASVMGRTPTFRQDAPLFAAIKACPVLSTVKLIAEPWDIGEGGYQVGNFPPPFAEWNDHFRDAARRFWLPRNLTTGEFACRFAASSDVFKRNGRTPGASVNLLTAHDGFTLRDCVCFNQKHNEANGEENRDGTNSNYSDNHGKEGLGGPLDLMERRRDSIHALLATLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNALTWLDWQQANRGLTTFTAALIRLRQQIPALTGNSWWEEGDGNVRWLNKNAQPLSADEWQNGPKLMQILLSDRFLIAINATLEVTDIVLPEGEWRAVPPFAGEDNPVITAVWQGPAHGLCVFQRG
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: LKA7B_MANHA
Sequence: MGNKLTNISTNLKSSWLTAKSGLNRTGQSLAKAGQSLKTGAKKIILYIPKDYQYDTDKGNGLQDLVKAAEELGIEVQKEESNDIAKAQTSLGTIHNVLGLTERGIVLSAPQLDKLLQKTKVGQAIGSTENITKGFSNAKTVLSGIQSILGSVLAGMDLDEALQNNSNELTLAKAGLELTNSLIENIANSVKTLDAFGDQINQLGSKLQNVKGLSSLGEKLKGLSGFDKTSLGLDIVSGLLSGATAALVLADKNASTSRKVGAGFELANQVVGNITKAVSSYILAQRVAAGLSSTGPVAALIASTVSLAISPLSFAGIADKFNHAKSLESYAERFKKLGYDGDNLLAEYQRGTGTIDASVTAINTALAAIAGGVSAAAAGSVVASPIALLVSGITGVISTILQYSKQAMFEHVANKIHNKIVEWEKNNPGKNYFENGYDARYLANLQDNMKFLLNLNKELQAERVIAITQQQWDNNIGDLAGISRLGEKVLSGKAYVDAFEEGQHLKADKLVQLDSAKGIIDVSNTGEAKTQHILFRTPLLTPGTEKRERVQTGKYEYITKLHINRVDSWKITDGAASSTFDLTNVVQRIGIELDNAGNVTKTKETKIIAKLGEGDDNVFVGSGTTEIDGGEGYDRVHYSRGNYGALTIDATKETEQGSYTVNRFVESGKALHEVTSTHTALVGNREEKIEYRHSNNQHHAGYYTKDTLKAVEEIIGTSHNDIFKGSKFNDAFNGGDGVDTIDGNDGNDRLFGGKGDDIIDGGNGDDFIDGGKGNDLLHGGKGDDIFVHRQGDGNDSITESEGNDKLSFSDSNLKDLTFEKVNHHLVITNTKQEKVTIQNWFREAEFAKTIQNYVATRDDKIEEIIGQNGERITSKQVDELIEKGNGKIAQSELTKVVDNYQLLKYSRDASNSLDKLISSASAFTSSNDSRNVLASPTSMLDPSLSSIQFARAA
What is the function of this protein?
Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture.  The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca(2+) and lysis of the host cell (By similarity).  This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis.  It has also weak hemolytic activity.
What are the official names of this protein?
Leukotoxin, Lkt.
What is the protein family that this protein belongs to?
Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein.
Protein: RLMH_PECCP
Sequence: MKLQLVAVGTKMPDWVQTGFTDYLRRFPKDMPFELLEIPAGKRGKNADIKRILEREGEQMLAAVGKGNRIVTLDIPGTRWETPQLAQQLERWKQDGRDVSLLIGGPEGLAPECKAAAEQSWSLSPLTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_RHOPT
Sequence: MKFLDEAKVYIRSGDGGNGCVAFRREKFIEFGGPNGGNGGRGGDIIVEAADGLNTLIDYRYQQHFKAQKGGNGMGSDRHGAGGKDIVMKVPVGTQIFDEDKETLIHDFTKVGERFVLAKGGNGGFGNAHFKSSTNRAPRHANPGLPGEERWIWLRLKLIADAGLVGLPNAGKSTFLSKVSAAKPKIADYPFTTLHPQLGVVNSDGREFVLADIPGLIEGAHEGAGLGDRFLGHIERCRVLLHLIDATCEHAGKAYKTVRGELEAYAETLVDKIEIVALNKIDAVEPDELKKQKDRLKRAAKKTPLLLSGVTGQGVPEVLRALVAVIGEAPVSDKAIGTADNPAEAKPWAPQDA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_CCMV
Sequence: MSTVGTGKLTRAQRRAAARKNKRNTRVVQPVIVEPIASGQGKAIKAWTGYSVSKWTASCAAAEAKVTSAITISLPNELSSERNKQLKVGRVLLWLGLLPSVSGTVKSCVTETQTTAAASFQVALAVADNSKDVVAAMYPEAFKGITLEQLTADLTIYLYSSAALTEGDVIVHLEVEHVRPTFDDSFTPVY
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging.
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the bromovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RL6_BORRA
Sequence: MSRIGKLPIKIADSVKVDIKDNFITVEGKRGKLSQEINSSIRVKIEDNNIIVERAFNNKQTRAFHGLYRSLIFNMVKGVSDGFSKSLTINGIGYRVEQQGNSLFFNLGYSTQFEYVIPEGINIRLDGNTKIAVEGIDKCRVGQVAAEIRSLKVPEPYKGKGIKYDNEVIRRKVGKSGVKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL6_ECOLC
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YJGA_ECOHS
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: PI3K1_DICDI
Sequence: MNSIESSSNDSNEINKNSNKNNTHLNSNYNNIYKNNSTSSNNNNNHNNIEIIGIDNNKNNNKNNNDNNNNNNNIDKKRKDSKNKQNQEINQEMSENKKIYNSNDSNCSSGSSSGGHVNNGHHILIEENERLEHENQEIQEIYKQKGMEFQKKDLRFGYDVNSNNNNNNGGGSSSGSSSGGSDESASNQPIIRTRNREGSILNLKKQGLVKEISQRFQTPDTASYTRPNANNISIKDKISILKKEQERRKQDSEVQQREKVIVLSADSSNIQIYHPSVLIEKMNSKLDTEEKPATTTTTTTTTSTSISTSTPTTTTTTTTNTSTTNDITIKPKTSPTKNNEERSQSPITTPKQPVEEIVKKVSTPKSNNTSKKTSSDTTPTGKTTKKDKKDKKDKSRDSGNLVIVNNTNNTSSNNNNNNNNNNNNETIIKRRGRVLVTPSSDLKKNIQIYFTIPINPPVNKTNKPNQLLSNTSQQFLKTLISNEIPIDCKINDINDTDAFSDLSASASSSSFITKSSQSLLNVQSLRVKAIKTSFNILFLMPNQSKKILQVKGSDTIENLKERIISDYLFNNNSNNNNNNCKYGADSYLILDFNDNPMERSLVLNKSDYILDKRAQGLIPKLKVIEKSTILDSDPSDELSPSEYEIIRKLIPGTDTWRGEEVEYFRRVTSRLRYEALPLIKGSIQSTLLVRLSPLPIPIVGNKILISIFLPITQVTKTLDLELNETADQFTNRLFTKNYSKHLPNVNSNDFILKVVGSSDFIHGPHDIRTFESIRNHIIQGTKPQLTLIQRPKPELDPQPFKPRFDYPPELIIDHSCSNAINCNNNNTNSTNNNNINFDNWDQITHISIREIKKPFRVKVMGSTRIPLSCIKDIDSSSVIVSISLYHGIECFSKAFTQPIIPPPFAFLAETLSVDWCEWLVFTNIDYSNLPVDARLSISVYSANETVDDVEEIKNLDEATKKLTPIGWINVMITDFKYQLRQGMVELSLWPSDFSNPLGTCSNNPSSSQSVGLTLEFEEFNLPVLFPRKTKFSTSVSVIEQPPTNINSNEMREFFEQITALDPLSDLKQEKYNQLWTLRHYSILFPQVLPRLMLSVPWTQATAVDEAISLLDRWPKLKPYESLELLDAKHANRKVREFAVTCLEDLSEDELLDILLQLVQVLKYEPFHDSKLSRFLLRKAILNRNIGHSFFWYLKSDLHDSNLSERFGILLESYLYACGAHRIELLKQMEVINNLTEVAKKIKPLKDQDRREFMIKEFESLEWPKRFHLTLNPRFESNGLIINKSKYMDSKKLPLRLSFTNTDMNADPIEVIFKAGDDLRQDMLTLQMIRLMDKLWQKEGLDLKLSPYGCISTGDMIGMIEVVLNSETTAKIQKSEGGGAASAFKLDPLANWILQHNKSDMEYQKAVDTFILSCAGYCVATYVLGIGDRHNDNLMVTKGGRLFHIDFGHFLGNYKKKFGFKRERAPFVFTPDFCYVMGGKESFKFSQFVNYCCTAYNIVRKNAKLFMNLFAMMVSTGIPELQSMEDLNYLKESFSIELSDEKAREKFVALIHESLATKTTQLNNFFHHLAHA
What are the official names of this protein?
Phosphatidylinositol 3-kinase 1, PI3-kinase, PI3K, PtdIns-3-kinase.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.