PharMolix/UniProtQA huggingface dataset:
Protein: RL29_ECOL6
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SYC_LEIXX
Sequence: MTLRLFDTKAGALRDFVPLRSGEVGMYVCGPTVQASPHIGHLRSALVYDQLRRWLTYRGLAVTLVRNVTDIDDKVLANAAAAQAEGGSEQWWALAYRFEREFTAASVALGVQAPTYEPRATASIPQMQEIIQRLIERGHAYAAGDGSGDVYFDVRSWPAYGELTRQSADSMEAAADADPRAKRDGRDFALWKGRKADEPDSAAFPSPWGEGRPGWHIECSAMSRRYLGPRFDIHGGGLDLRFPHHENELAQSAAAGDSFANYWVHNGLVNVNGQKMSKSLGNSVSAAELLGAARPLAVRYSLGSAHYRSTIDYHDGSLSEAEAALERIAGFFERVDRRLAGTRFTGSGSEVVPIAFAEAMDDDLAVPQALAVLHETVRSGNAALDAEDLEAAAAARGQVFAMTEVLGINPLSPQWRQTGSSAAEQALGTLVERLLHNRQEARQVRDFVAADRIREELTGAGITIEDTPTGCHWSIEA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP3_FRAAA
Sequence: MNYFEGTVLGLVQGLTEFLPVSSSAHLRITAALAGWDDPGAAFTAVTQIGTETAVLIYFRRDIARIVRAWALSWTRREMRKDTDARVGWLVLLGTIPIGLLGVTLQDAIEGPFRDLRLIATTLIVLGLILGGADWYASKGRPRGRHSLPRPRKTLRDLSVRDGLLYGLAQSAALIPGVSRSGATISGGLLLGYTREAAARYSFLLAMPAVLASGVFELKSIGGDREGGDGEEVSWGPTIVATVVAFATGYAAIAWFLRYISTRSFAPFVLYRVALGLLLLALLAGGAISADAGAAAD
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 3, Bacitracin resistance protein 3, Undecaprenyl pyrophosphate phosphatase 3.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DXR_ARTS2
Sequence: MQPRRIVLLGSTGSIGTQAIDVVDGAPHLFEVVALSAGGGNLELLARQAVHTKAKAVGTASGDATALQRLIDDAARATGVAGYRPEIITGPDASTRIAEIEADVVLNGITGSIGLAPTLAALKSGATLALANKESLIVGGALVKAAAREGQIVPVDSEHSAIAQCLRSGTAAEVDRLILTASGGPFRGRTREELHNVSPEEALAHPTWDMGLMVTTNSASLVNKGLEVIEAHLLFDIPLDRIDVVVHPQSVVHSMVQFVDGSIIAQASPPDMRLPIALGLGWPDRVPKAATPCDWTQATSWTFEPLDAEAFPAVNLAKDAAKQGSTYPAVFNAANEEAVMAFHAGRIRFTDIVDTIEAVLSEHPGSSGLTVESVLDAEAWARARTHERLAVSSL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: PBPA_RICCN
Sequence: MYKSLLFCLKIFVFLILVGCGITAYIIYHYSRDLPDYSQLARYYPPSVTRIYSRDGKLMEEYAFERRVFVPINSVPSSLIESFIAAEDKNFYNHPGVDLFGIVRAAFLNISNYLHHRRMEGASTITQQVVKNFLLTNEVSLERKIKEAILSYMISRVFTKDQILELYLNQTFFGRGAYGVAVAAQNYFNKSVEELTIAESAFIAALPKAPSELNPERNYARVKARRDYVITRMFEDGYITRDAAKEAMDSPIVLRKRAKEETVTADYYAAQVREEVIRMLNSKEVFYTGGLTIITSLDAKMQQLAENSLRKGLREFDRRCGFRKPIANISLDNWQGELKKLPTPPSLLEYKLAVVLDVADNHVEIGLIDGSKSKMPIAEMKWARSNFKSVKTLLKKGDVIVVEAIKEGYALRQIPEVNGAIMVMNPNTGQVLASVGGYDFSTSKFDRVTQALRQPGSLSKTFVYLAALENGVKPNQIFNDGPIEISQGPGMPSWRPKNYEGKFLGEITMRTGLEKSRNLITVRVATAVGLTKIVDIIKRFGINNEPKKVYSMVLGSIETTLSRMTNAYAIIANGGKKVEPHFVELIKDRNGKIIYRRDDRECLACNVSDSNLDTAILEIPKEYIYRVTDEASDYQITSFLTGAIDRGTGYAAKKLGKIIGGKTGTSNDSKDTWFVGFTPKIVVGSYVGYDTPKELGKRATGSNVVLPIFIDFMSNAYKDKPSLPFKVPDSIKLIAVDSATGKITPGGTVIEAFKVNNVQMLENEDMIDNQDNNDIFDYVPSKEDQSQEIY
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
What are the official names of this protein?
Penicillin-binding protein 1A, PBP-1a, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: EXBD1_XANCB
Sequence: MAFSSGNSGGPMADINVTPLVDVMLVLLIIFIITAPLMSHKVKVELPEANLIQKEDAEKRAAPITLAVKEDGSLYWNDEPISKEALESRLSTAAQQTPQPPLNLRGDRTTKMRTINEITKIAQGQGMLDVGFVATKEKGQ
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
What are the official names of this protein?
Biopolymer transport protein exbD1.
What is the protein family that this protein belongs to?
Belongs to the ExbD/TolR family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: SAP7_ARATH
Sequence: MGSEENNSTSFPPTEPKLCDNGCGFFGSPSNMNLCSKCYRSLRAEEDQTAVAKAAVKNSLKLPSCSIIAPGQKHPLEIKPAHLETVVVTAEPSSVPVAAEQDEAEPSRPVRPNNRCFSCNKKVGVMGFKCKCGSTFCGSHRYPEKHECSFDFKEVGRDAIAKANPLVKADKVQRI
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 7, AtSAP7.
Protein: OTSA_MYCTA
Sequence: MAPSGGQEAQICDSETFGDSDFVVVANRLPVDLERLPDGSTTWKRSPGGLVTALEPVLRRRRGAWVGWPGVNDDGAEPDLHVLDGPIIQDELELHPVRLSTTDIAQYYEGFSNATLWPLYHDVIVKPLYHREWWDRYVDVNQRFAEAASRAAAHGATVWVQDYQLQLVPKMLRMLRPDLTIGFFLHIPFPPVELFMQMPWRTEIIQGLLGADLVGFHLPGGAQNFLILSRRLVGTDTSRGTVGVRSRFGAAVLGSRTIRVGAFPISVDSGALDHAARDRNIRRRAREIRTELGNPRKILLGVDRLDYTKGIDVRLKAFSELLAEGRVKRDDTVVVQLATPSRERVESYQTLRNDIERQVGHINGEYGEVGHPVVHYLHRPAPRDELIAFFVASDVMLVTPLRDGMNLVAKEYVACRSDLGGALVLSEFTGAAAELRHAYLVNPHDLEGVKDGIEEALNQTEEAGRRRMRSLRRQVLAHDVDRWAQSFLDALAGAHPRGQG
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose and in the production of glycogen and alpha-glucan via the TreS-Pep2 branch involved in the biosynthesis of maltose-1-phosphate (M1P).  Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Probably also able to use ADP-Glc, CDP-Glc, GDP-Glc and TDP-Glc as glucosyl donors.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: FABA_BRUA2
Sequence: MAEQKSSYGYEELLACGRGEMFGPGNAQLPLPPMLMIHRITEISETGGAFDKGYIRAEYDVRPDDWYFPCHFQGNPIMPGCLGLDGMWQLTGFFLGWLGEPGRGMALSTGEVKFKGMVRPHTKLLEYGIDFKRVMRGRLVLGTADGWLKADGELIYQATDLRVGLSKEGSAQ
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_RICBR
Sequence: MPELPEVETLKNSLESKLIGLVIKKVEFKRDNLRYKLSADLADQIVNTNIINVRRRAKYLIIDFNNNHSLIVHLGMSGRFTLQPNNYEVKKHDHVVFNLSNNEKLIFNDTRRFGMIYSFHTELLEKDFFANLALEPLSDSFELQYLKSKLMNKKVPIKNLLMDNRIVVGVGNIYASESLHLAKIHPDKFGKDLNDDEIKNLIAAVKNVLSKAIIAGGTTLKDFVNGDNKPGYFTQQLMVYARDGQECLSCSSSIIKTKHSGRSTFYCKSCQKA
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PROB_SHEHH
Sequence: MNLSEISYRRVVVKLGTSVLTSGSLKLDKAHMVELARQMACLMKAGVEVVLCTSGAIAAGKEHLGYPQLPDTIASKQLLAAVGQSQLILAWSQLFSIYGLHVGQLLLTRADLHDRERYLNARDSLNALLNNGIIPIINENDAVATAEIKVGDNDNLSARAALLCDADLLILLTDQKGLFDADPRKNPDAKLITEVQNIDDSLRMLAGGAVSGLGTGGMATKLEAADIARRAGVEVVIASGHHKDVIQNVVCAKPVGTHFTALEHPLESRKQWILAGPKARGQVVLDTGAITAVTQKGRSLLSKGIIEVNGLFQRGDTIELVDTKGKVYAKGMSRYGSLDVSKIAGKHSDNIEEILGYDYGDAVVHRNDMVVL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBPL1_ENTH1
Sequence: MSSQSSPISLTNNDLEISSNNNKPIIKQLPVPTNEIEKPVIQNIVATVELDCTINLQDVVRRVRNAEYNPKRFGALIIRITNPKTTALVFHSGKLVVTGGKTVDDSRLAGRKYARILQRLGYNVKFNHFKIQNVVASCDMKFAISLKELIQLAPKITKYEPEIFPGVVYRLADPKMVLLIFASGKIVFTGGKEIEQINKAFSEIYKILLQVANNDN
What is the function of this protein?
TATA box-binding transcription factor.  Members of the TBP family are differentially required to regulate transcription and development during early embryogenesis.
What are the official names of this protein?
TATA-box-binding protein-like 1, EhTRF1.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: SLD5_DICDI
Sequence: MMSGEYGDFNNTNNKELSLLDKLKKAWINEKYAPNLLNYEDVIIKEVMEKIEEKESLCASAISNINLQFTANIYEMEIERLKYIIKCYLVQRIKKIDKFYSSILLEIENDEYDSYKLLSEFEINYCQKYKALMDGYFKNTLLNSIPKDFQKMDSNSINRPFLNTFVFCKPREDLGDFLVDDETIDFKKTSIYFLKYLPIKSLVEGGKMDLI
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.
What are the official names of this protein?
DNA replication complex GINS protein SLD5, GINS complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the GINS4/SLD5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEMA_I72A5
Sequence: MIAIIVVAILATAGRSDKICIGYHANNSTTQIDTILEKNVTVTHSVELLENQKEERFCKILKKAPLDLKGCTIEGWILGNPQCDLLLGDQSWSYIVERPTAQNGICYPGVLNEVEELKALIGSGERVERFEMFPKSTWTGVDTSSGVTRACPYNSGSSFYRNLLWIIKTKSAAYSVIKGAYNNTGNQPILYFWGVHHPPDTNEQNTLYGSGDRYVRMGTESMNFAKSPEIAARPAVNGQRGRIDYYWSILKPGETLNVESNGNLIAPWYAFRFVSTSNKGAVFKSNLPIENCDATCQTVAGVLRTNKTFQNVSPLWIGECPKYVKSESLRLATGLRNVPQIETRGLFGAIAGFIEGGWTGMIDGWYGYHHENSQGSGYAADRESTQKAVDGITNKVNSIIDKMNTQFEAVDHEFSNLERRIDNLNKRMEDGFLDVWTYNAELLVLLENERTLDLHDANVKNLYERVKSQLRDNAMILGNGCFEFWHKCDDECMESVKNGTYDYPKYQDESKLNRQEIESVKLESLGVYQILAIYSTVSSSLVLVGLIIAVGLWMCSNGSMQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: SYM1_ALKOO
Sequence: MNIFIGGAWPYANGSLHLGHVAALLPGDVMARYFRAKGENVLYVSGSDCHGTPISIRAKNENVSPQEIAEQYHKEFKYCFEELGFSYDYYSRTDDAYHKEEVQRIIKLLYENEFIYEKEVEQLYCADCNQFLPDRFVEGICPVCKNIARGDQCDVCSTILDPLDLHHRKCKICGSEPEIKNGNQLFFKLSKFQEMLQNHLEDSKKKWRVNALNNTERYLKEGLQDRAISRDLNWGIEIPIKGYEEKRVYVWIDAVLGYYTVSKKWGIERNRDWETFWSKEAIHYFIHGKDNIPFHSLIFPALLNGIGYKKMPDRIISSEYITLEGKKISTSNNWAVWVPDMIERYNVDSIRYFLLANGPEKRDADFSWREFINSNNGELLGAYGNLVNRTFVFVKKYFNNTIPVGKLEEEIERATEKLYDEVGKSIESGNLRLALEQIFQFIRSINKYFDEETPWTTVNTNIDDCSNTIYNCLFSIINIANLLNPFLPSSSAKIKEWMGCKEASWNKLSLSSGIQLGDFNILFERLDKKLAEEELAKLGR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase 1, Methionyl-tRNA synthetase 1, MetRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP8_CORCR
Sequence: MPQLNPNPWLFIMLMSWLTFSLIIQPKLLPFTPINPPSNKTPTTTKTSPWTWPWT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: PSA4_MOUSE
Sequence: MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAVKVLNKTMDVSKLSAEKVEIATLTRESGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQREKDK
What is the function of this protein?
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit alpha type-4, Macropain subunit C9, Multicatalytic endopeptidase complex subunit C9, Proteasome component C9, Proteasome subunit L.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9 (By similarity). Colocalizes with TRIM5 in the cytoplasmic bodies (PubMed:22078707).
Protein: PTH_BORBZ
Sequence: MGLLILGLGNPGLEFSLTRHNVGFSLLDKIVSKNGLFLKRKKKYEYSELKMISGRVILVKPLTYMNLSGSLFPSIFSDFYMCIKNLLVVLDNVDLPLGKCRLKERGGVSTHNGLRSISSVLGSSNYSRLYIGVGSNLMRDIKSFVLSRFCKDEMDRLEKLYDFLSDELIDISEANFKNKVQKINSSNF
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS2_THEPD
Sequence: MIVIVAYDISDEDRRGRLRRYLRRLGLARVNRSVYAGPGTATTAELVAERAKEIVEEGDSVFVIVVREDEYQRAHVFDGRDYYIVSERKYEVY
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: MIC60_YEAS8
Sequence: MLRTTASRKIVLRRGLASINTGTTVASKKASHKFRNTFWTIALSATAFYAGGIIYSQKNDKFGDFFSNNVPFAEDLLETYEHYHDRPTLFLEDSWDGLKAKSNDLLSGLTGSSQTRRSNRENIEVKKILSLEPLNIETENSDPQLKEIIGSLNDLINSLNDSNLSIPESEFNSIKKSNQNMLTNLSQLNETLKEALSNYMIQRTSEVITELNTQYENSKREFEKNLQKNLLQEVDEFKENLTKQKDKELEEKLKANEELLQAKHANGVGLLSITQVKEFNKIIKDKIEKERNGRLAHLEEINSEVNDLSKSIDRSSKILSKNEALVQLTFQVDEIKSRINNNNLPDVNIDKELSRLKLLSNLLSTFNKKSCCDDGDCCSCKKGNKNEGKEGKISCKCKPKTNPPSLLSVALDELESTCSGKKILSNEQIYNRWNLLADDFKTASLLPPNSGILGQLTAKVFSLFLFTKTGNPSNATDFDSVYARVGDNLRVSNLNDAVEEVVSLKGWPHKVCESWIEDARRKLEVQRLVEILDCEIRTL
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ASSY_RUEPO
Sequence: MSAPKKVVLAYSGGLDTSIILKWLQTEYGCEVVTFTADLGQGEELEPARKKAELLGIKPENIHIEDVREEFVRDFVFPMFRANAVYEGLYLLGTSIARPLISKRLVEIAAEHGADAVAHGATGKGNDQVRFELSAYALNPEIRVIAPWRLWDLTSRTRLLEFAEAHQIPISKDKRGEAPFSVDANLLHTSSEGKVLEDPGVEAPDYVAQRIVAVEDAPDTPEFIEVTFEKGDAVAINGEAMSPATILTRLNELGGKHGIGLLDFVENRFVGMKSRGVYETPGGTILLEAHRGIEQITLDSGAGHLKDSIMPRYAELIYNGFWFSPEREMLQALIDKSQEHVTGTVRLKLYKGSARTVARWSDHSLYSEAHVTFEEDAGAYDQQDAKGFIQLNALRLKLLATRNRRVAGK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_ACIBT
Sequence: MNINLTLIGQAIAFAFFVAFCMKFVWPPLINAISERQRKIADGLNAAEKAKADLADAQAQVKQELDAAKAQAAQLIEQANRRAAQLIEEARTQAAAEGERIRQQAKEAVDQEINSAREELRQQVAALAVTGAEKILNQQVDAEAHNAMLSQLAAKL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PPOB_SOLLC
Sequence: MASVVCNSSSSTTTTTLKTPFTSLGSTPKPSQLFLHGKRNKTFKVSCKVINNNGNQDETNSVDRRNVLLGLGGLYGVANAIPLAASATPIPSPDLKTCGRATISDGPLVPYSCCPPPMPTNFDTIPYYKFPSMTKLRIRTPAHAVDEEYIAKYNLAISRMRDLDKTEPLNPLGFKQQANIHCAYCNGAYIIGGKELQVHNSWLFFPFHRWYLYFYERILGKLIDDPTFALPYWNWDHPKGMRLPPMFDREGSSLYDERRNQQVRNGTVLDLGSFGDKVETTQLQLMSNNLTLMYRQMVTNAPCPLLFFGAPYVLGNNVEAPGTIETIPHIPVHIWAGTVRGSKFPNGDVSYGEDMGNFYSAGLDPVFYCHHGNVDRMWNEWKAIGGKRRDISEKDWLNSEFFFYDEHKNPYRVKVRDCLDTKKMGYDYAPMPTPWRNFKPKSKASVGKVNTSTLPPANEVFPLAKMDKTISFAINRPASSRTQQEKNEQEEMLTFNNIRYDNRGYIRFDVFLNVDNNVNANELDKAEFAGSYTSLPHVHRAGENDHIAKVNFQLAITELLEDIGLEDEDTIAVTLVPKKGGEGISIENVEIKLVDC
What is the function of this protein?
Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.
What are the official names of this protein?
Polyphenol oxidase B, chloroplastic, PPO, Catechol oxidase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: DNAJ_BACFN
Sequence: MAEKRDYYEVLEVTKESTVEEIKKAYRKKAIQYHPDKNPGDKEAEEKFKEAAEAYDVLSNPDKRARYDQFGHAGMSGAAGNGGPFGGFSGGMSMDDIFSMFGDIFGGHSGGGFGGGFGGFGGFGGGGSQQRKFRGSDLRVKVKLNLKEISTGVEKKFKLKKYVPCSHCHGTGAEGNSGSETCPTCKGSGSVIRNQQTILGTMQTRTTCPTCNGEGKIIKDKCKVCGGEGIEYGEEVVTVKIPAGVAEGMQLSMGGKGNAGKHNGIPGDLLILVEEEPHPELIRDENDLVYNLLLSFPTAAIGGAVEIPTIDGKVKVKIEAGTQPGKVLRLRGKGLPSVNGYGTGDLLVNVSVYVPETLSKEEKSTLEKLEESKNFKPSTSIKEKIFKKFRSLFD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.