PharMolix/UniProtQA huggingface dataset:
Protein: PYRC_ACIB3
Sequence: MNSITLLQPDDWHAHLRDGLALKRTVPDLAKQFARAICMPNLVPPVKTVEEALAYRERILAHVPEGNNFDPRMVLYFTDHTSPDEVRKIKESEHVNAIKLYPAGATTNSDNGVSDIRKVYAVIEQLEEHQVPLLLHGEVTHNHVDIFDREKRFLDEVLSPLLKQFPKLKVVLEHITTSDAAHFVLEQDRNVAATITPQHLLFNRNDMLVGGIKPHFYCLPILKRQTHQTTLLEVATSGNPKFFLGTDSAPHAQNAKENACGCAGCYSAPNAIELYAQAFDQVGKLERLEGFASHFGADFYGLPRNTSTITLVKEDNLVPESFDYLDNQKIIPLHAGKTLQWRKV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: Y2604_STAAW
Sequence: MKKQDISVKTVVAIGIGAAVFVILGRFVVIPTGFPNTNIETSYAFLALISAIFGPFAGLMTGLVGHAIKDFTTYGSAWWSWVICSGIIGCLYGWIGLKLNLSSGRFSRKSMIYFNIGQIIANIICWALIAPTLDILIYNEPANKVYTQGVISAVLNIISVGIIGTILLKAYASSQIKKGSLRKE
What are the official names of this protein?
UPF0397 protein MW2604.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEU3_HAEIN
Sequence: MQSYNIAVLAGDGIGPEVMAEAIKVLNRVQEKFGFKLNFNEFFVGGAAIEHCGYPLPAETLKGCDQADAILFGSVGGPKWTNLPPDQQPERGALLPLRKHFKLFCNLRPATLYKGLEKFCPLRADIAAKGFDMVVVRELTGGIYFGQPKGREGDGVQTKAFDTEVYYKYEIERIARAAFEAAMKRNKKVTSVDKANVLQSSILWRETVTEMAKDYPEVTLEHIYIDNATMQLIKSPESFDVLLCSNIFGDIISDEAAMITGSMGMLPSASLNEEGFGLYEPAGGSAPDIAGKGIANPIAQILSAAMMLRYSFNLNEAADAIESAVQKVLASGHRTADLADDSTPVSTAEMGTLITQAI
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHSH2_HUMLU
Sequence: MVTVEEVRKAQRAEGPATILAIGTATPANCILQSEYPDYYFRITNSEHKTELKEKFKRMCDKSMIRKRYMHLTEEILKENPNLCAYEAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPNDTHLDSLVGQALFGDGSAALIIGADPIPEIEKPTFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFKPLGISDWNSLFWIAHPGGPAILDQVESKLALKPEKLRATRHVLGEYGNMSSACVLFILDEMRRKCAEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVGI
What is the function of this protein?
Involved in the biosynthesis of prenylated phenolics natural products which contribute to the bitter taste of beer and display broad biological activities (Probable).  Chalcone synthase that can use 4-coumaroyl-CoA to produce 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can, under specific conditions, spontaneously isomerize into naringenin (By similarity).
What are the official names of this protein?
Chalcone synthase H2, CHS_H1-1539, Naringenin-chalcone synthase CHS_H1-1539.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOSR_BACSU
Sequence: MRLIKLEQPNCNPCKMVSNYLEQVNIQFETVDVTQEPEVAARFGVMGVPVTILLSDQGEEVNRSVGFKPNELDELLKELR
What are the official names of this protein?
SPbeta prophage-derived thioredoxin-like protein YosR.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: GPDA_FRATF
Sequence: MQKNILVLGAGAWGTALALQLAYRGHNVRINSWKAEHNEQMLKDNNNHKYLPSIEKFPSRLKAIQDWQANIIEFDSILVATPSSGFKNTILELKECILPQQNIISATKGFCHDSYALLSEIAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINYARYVQELFSNENFRCYTTTDIIGAQVGGAVKNVLAITAGIAAGMEFGVNAHAALITRGLAEIKKLGLKLGANSETFIGLSCLGDLLLTCSDNQSRNRRFGLYLGQGMTIQQALKEVNNVVEGYFTAKAVYNFAKKHNVEMPLVFATYRILYEAADPRDIVKELMTRQLKNEN
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_KLUIN
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIIAEGLKAVAAGMNPMDLKRGIDKAVVAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLEDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDMGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRKQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVDDALHATRAAVEEGVVAGGGVALIRVASKLSNLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKAGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKGDAPDLRAAGMGG
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCRB_STAAE
Sequence: MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVVFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHMYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: END4_ACTPJ
Sequence: MKYIGAHVSASGGVENAVLRAVEIGANAFALFTKNQRQWKAPALKADTIEKFKRFCKAHQFSPEHILPHDSYLINLGNPEAENLAKSREAFIDEMERANQLGLKLLNFHPGAHLNKISESECLARIAESINIAVDKVPNVIAVIENTAGQGSNLGYRFEHLAEIIDQVEDKNRVGVCLDTCHLFSAGYDISSLESCEQTFSEFERTVGFQYLRGMHLNGSKTPLGSRVDRHHTLREGTIGTDFCKFIMQDDRFDNIPLILETIQPEIWTEEIKFLRTLAK
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: Y714_RICPR
Sequence: MPQLLTPPLSPLIIAVLNGNIEYTSELLQNGVDIDVRDKNGNSALHIAASKGYTKIATMLLLYGATIDAPNFELATPLHYAAANNYKDLTQYLLNMNANKSAVNKYN
What are the official names of this protein?
Putative ankyrin repeat protein RP714.
Protein: XERC_ACTSZ
Sequence: MQNALQKYYDFLRIERRLSPYTLTNYRRQLSAVTELLTQNGIRSWQQVTPSVVRFILAESRKAGLHEKSLALRLSALRQFLAYLVVQEELKVNPATGISAPKQGKYLPKNIDQEQIGKLLDNRSNEPIDIRDRAMLELMYSSGLRLSELHGLDLNHVNLQSREVRVLGKGSKERILPVGHQALDAVLDWLQVRLRFNPKDNALFVSSQGGRLTPRAIQKRMEIWGVKQGLSTHLNPHKLRHSFATHMLEASADLRAVQELLGHSNLATTQIYTHLDFKHLTDVYDQAHPRAKRKG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_BLOFL
Sequence: MKKNIHPQYNVISASCSCGNVIHVRSTLKHNINLDVCDACHPFYTGTQRIIDTRGRVNLFNKRFNKNNKNPFI
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL9_MACFA
Sequence: MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATIRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_VIBVY
Sequence: MSYFEAFVLALIQGLTEFLPISSSAHLILPSAILGWEDQGLAFDVAVHVGTLAAVVIYFRKEVITLFAALFASIFKGERSKEAKLAWMIVIATIPACIFGLVMKDVIEVYLRSAYVIATTTIIFGLLLWWVDKNASLLDDEYQAGWKKALFIGIAQALAMIPGTSRSGATITAALYLGFTREAAARFSFLMSIPIITLAGSYLGLKLVTSGEPVHVGFLLTGIVTSFISAYLCIHLFLKMISRMGMTPFVIYRLILGVGLFAYLLMA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CEP70_MACFA
Sequence: MFPVAPKPQDSNQPSDRLMTEKQQEEAEWESINVLLMMHGLKPLSLVKRTDLKDLIIFDKQSSQRMRQNLKLLVEETSRQQNMIQELIETNQQLRNELQLEHSRATNQEQRANDLEQIMESVKSKIGELEDESLNRACQQQNKIKDLQKEQRTLQVKCQHYKKKRTEQQETIASLQTEVCRLRKEEEDRIVTQNRVFAYLCKRVPHTVLDRQLLCLIDYYESKIRKIHTQRQYKEDESQSEEENDYRSLDASPTYKGLLMSLQNQLKESNSQIDALLSEKLNLQKDSETRPTQHELRLYKQQVKKLEKALKKSVKLQELISPKKAEDTEKKDEPSKYNQQQALIDQRYFQVLCSINSIIHNPRAPVIIYKQSKGGAQNFNKDLIQDCGFEHLVPIIEMWADQLTSLKDLYKSLKTLSAELVPWHNLKKQDENEGIKVEDLLFIVDTMLEEVENKEKDSNMPNFQTLQAIVSHFQKLFDVPSLNGVYPRMNEVYTRLGEMNNAVRNLQELLELDSSSSLCVLVSTVGKLCRLINEDVNEQIMQVLGPEDLQSIIYKLEEHEEFFPAFQAFTNDLLEILEIDDLDAIVPAVKKLKVLSY
What is the function of this protein?
Plays a role in the organization of both preexisting and nascent microtubules in interphase cells.  During mitosis, required for the organization and orientation of the mitotic spindle (By similarity).
What are the official names of this protein?
Centrosomal protein of 70 kDa, Cep70.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: GLMU_EXIS2
Sequence: MNHFAVILAAGKGTRMKSKLYKVLHPVAGKPMVQHVVDQLTTLGVTRQVVIVGHGAESVKEVLGTSVEYALQSEQLGTGHAVQMAEPVLGQEKGSTLVVCGDTPLLTSETLQSLLQHHAETGAKVTVLTAHADDATGYGRIVRGEDGNVSKIVEHKDANAEELLIKEINTGTYVFDNEMLFEALKQVKNDNVQGEYYLPDVIEIAKADGETIAAYAASTFEETIGVNDRVALAQAETSMRKRTNEHWMRQGVTFIDPASTYIGPDVVIGSDTVLYPGTQLLGNTTIGSECIIGPNSDIRNSEVADQAVVRQSVVTDSKIGPAAQVGPFAHLRQQAVLGANTRIGNFVEVKKSTFGEGSKSAHLSYVGDATIGTNVNLGCGSITVNYDGTNKFQTVIEDDAFIGCNVNLIAPVTVGKNALVAAGSTVTDDVPENGLAIARERQTTKPDYR
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPPMT_STRLS
Sequence: MAAASAPVPGPGGASSTARGRIPAPATPYQEDIARYWNNEARPVNLRLGDVDGLYHHHYGIGAVDHAALGDPGDGGYEARLIAELHRLESAQAEFLLDHLGPVGPGDTLVDAGCGRGGSMVMAHQRFGCKVEGVTLSAAQAEFGNRRARELGIDDHVRSRVCNMLDTPFEKGTVAASWNNESSMYVDLHDVFAEHSRFLRVGGRYVTVTGCWNPRYGQPSKWVSQINAHFECNIHSRREYLRAMADNRLVPQTVVDLTPETLPYWELRATSSLVTGIEEAFIESYRDGSFQYVLIAADRV
What is the function of this protein?
Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP).
What are the official names of this protein?
Geranyl diphosphate 2-C-methyltransferase, GPP methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the geranyl diphosphate 2-C-methyltransferase family.
Protein: YGFZ_EDWI9
Sequence: MNLNAPFSPQPPLAAEHLPLTLMRLDDWLPINVSGPDAQSYLQGQLTADLPSLAATQHTLCGHCDAQGKLWSSLRLLRRRDGFTYLLRRSVATLQMLELKKYAVFAKASIVSDEGAVLLGVAGAQASEALGALFPRLPDADAPLLQAGRSHLLYMAWPQPRYLLICDDADEAERIFAPLSARARLADSAQWLALDIESGIPLIDEPNCDSFLPQAVNLQALGGISFTKGCYSGQEMVARAKYRGANRRALFWLRGSAERLPHASEDLELRLGDSWRRSGTVLAAQRLADGGVYLQAVLSSDLPADSVLRVRDDARSQLTLSPLPYSTDQQE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR2_XYLFA
Sequence: MKLLVIGSGGREHALAWKLAHSRRVSEIIVAPGNAGTATETKCRNAPVKVTDLDGLLALAQREAVNITVVGPEVPLVAGIVDCFRAAGMRIFGPTAAAAQLEGSKAYAKDFLARHGIPTARYAVHTNVDAAISDVRQQGAPIVIKADGLAAGKGVIVAMTVTEAEAAIRDMLSGNAFGHAGARVVIEEYLDGEEASFISMVDGTHALPMATSQDHKRVSDGDIGPNTGGMGAYSPAPIITDEIHARVMREIVNPTVTGMIADGTPFMGFLYAGLMIDVHGAPKVIEFNVRFGDPETQPMMMRLQSDLLDLIEAALNGDLDKVQAQWDPRPSLGVVMAARPYPKAPITGEIISGLDALPANVKVFHAGTALDAAGCVVTAGGRVLCVTALGSNVSEAQRHAYAGVASLHWANAFQRSDIGWRAIMREHTVTLNVHGPV
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: NUD12_MACFA
Sequence: MSSVKRSPKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENYFSKTLLDRKSEKRNNADWLLAKESHPATVFILFSDLNPLVTLGGNKESFQQPEVRLCQLNYKDIKDYLAQPEEITLIFLGVELEMKDKLLNYAGEVPREEEDGLVAWFALGIDPIAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNGTKIEEGGYKRVCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTRCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVSCQPWPMPSSLMIGCLAVAVSTEIKVDKNEIEDARWFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some RNAs; in contrast to the canonical N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay.  Preferentially acts on NAD-capped transcripts in response to nutrient stress (By similarity).  Also acts on free nicotinamide adenine dinucleotide molecules: hydrolyzes NAD(H) into NMN(H) and AMP, and NADPH into NMNH and 2',5'-ADP.  May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle (By similarity).  Regulates the levels of circadian clock components PER1, PER2, PER3 and CRY2 in the liver (By similarity).
What are the official names of this protein?
NAD-capped RNA hydrolase NUDT12, DeNADding enzyme NUDT12, NADH pyrophosphatase NUDT12, Nucleoside diphosphate-linked moiety X motif 12, Nudix motif 12.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome. Cytoplasmic granule. Note=Localizes to cytoplasmic granules in the presence of BLMH.
Protein: ZDH18_MOUSE
Sequence: MKDCEYQQISPGAAPPPASPGARRPGPAAPPAPSPGPAPGAPRWSGSGSGSGSLGRRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILSTTILFFVFDCPYLARTLTLAIPIIAAILFFFVMSCLLQTSFTDPGILPRATICEAAALEKQIDNTGSSTYRPPPRTREVMINGQTVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLLSQGSNFLSALKKTPASVLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSSKRGGEASVNPYSHKSIITNCCAVLCGPLPPSLIDRRGFVQSDTALPSPIRSDDPACGAKPDASMVGGHP
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates, such as CGAS, HRAS and LCK (PubMed:15603741, PubMed:35438208).  Palmitoylates HRAS and LCK (PubMed:15603741).  Acts as a negative regulator of the cGAS-STING pathway be mediating palmitoylation and inactivation of CGAS (PubMed:35438208).  May also have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and therefore regulate G protein-coupled receptor signaling (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC18, DHHC domain-containing cysteine-rich protein 18, DHHC-18, Zinc finger DHHC domain-containing protein 18.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: IBSC_ECOLI
Sequence: MMRLVIILIVLLLISFSAY
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system.  Overexpression causes cessation of growth and rapid membrane depolarization.  Overexpression induces stress-response, the psp phage shock and a number of membrane protein genes.
What are the official names of this protein?
Small toxic protein IbsC.
What is the protein family that this protein belongs to?
Belongs to the Ibs toxic protein family.
Protein: Y1599_HAEIN
Sequence: MLPKSSLKETQQALANAIRLGNADPLNGYAASRLAVYTRLVRNNAFGFIDRCFVEAPLHIEPEYWKNAKENFVQNGNAHSPYFQDIAGEFLLFCQEKEIFDTNILALMDFENTQLLAEVSLAKVPEKFEWNRHSVMQLSGAAYLKSYDVDFLSSDFKQFDDTPIQAIIWRDSDFRIQQQILSELDYWLLSYLQEQPNSLENVLSALNTMVEDSTSIIPLLEQVWMKWVTSEVIYPEQR
What are the official names of this protein?
Uncharacterized protein HI_1599.
Protein: OPSD_SPHSP
Sequence: MSLINEPSYSAYSWGGQGGYGNQTVVDKVLPEMLHLIDPHWYQFPPMNPLWHGLLGFVIGCLGFVSVVGNGMVIYIFSTTKGLRTPSNLLVVNLAFSDFLMMLSMSPPMVINCYYETWVLGPFMCELYALLGSLFGCGSIWTMVMIALDRYNVIVKGLAAKPMTNKTAMLRILGIWAMSIAWTVFPLFGWNRYVPEGNMTACGTDYLNKEWVSRSYILVYSVFVYFLPLATIIYSYWFIVQAVSAHEKQMREQAKKMNVASLRSAENANTSAECKLAKVALMTISLWFFAWTPYLVTDFSGIFEWGKISPLATIWCSLFAKANAVYNPIVYGISHPKYRAALNKKFPSLACASEPDDTASQASGATTVSDEKSASA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Rhodopsin, Opsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LEPA_SHEB2
Sequence: MKQIRNFSIIAHIDHGKSTLSDRLIQVCGGLTDREMDAQVLDSMDLERERGITIKAQSVTLDYKAKDGLVYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTALDMNLDVVPILNKIDLPQADPERVAAEIEDIVGIDAIDAVRCSAKTGVGVDEVLEVIVAKIPPPEGDPNAPLQALIIDSWFDNYLGVVSLVRIKHGSLKKGDKFKVMSTGQNHTADRVGIFTPKQTDKTELKTGEVGFVIAGLKEIHGAPVGDTLTLAKNGAEKPLPGFKKVKPQVYAGVFPISTDEYENFRDALNKLSLNDASLFFEPESSSALGFGFRIGYLGLLHMEIVQERLEREYNLELITTAPTVVYEVVMTSGETIYVDNPSDLPAINNIEEMREPIVEANILVPKEYLGNVITLCIEKRGTQVNMVYHGNQVAVTYHLPMAEVVMDFFDRLKSTSRGYASLEYNFIRFDPADMVRLDILINGDRVDALAMVIHRSNIRHRGLALVDKMKELIPRQMFDIAIQAAVGSQIIARSTVKALRKDVTAKCYGGDVSRKKKLLNKQKEGKKRMKQVGNVEVPQEAFLAVLKLNE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PSB9_RAT
Sequence: MLQAGAPTAGSFRTGEVHTGTTIMAVEFDGGVVVGSDSRVSAGAAVVNRVFDKLSPLHQRIYCALSGSAADAQAIADMAAYQLELHGLELEEPPLVLAAANIVKNISYKYREDLLAHLMVAGWDQHEGGQVYGTMGGMLIRQPFAIGGSGSTYIYGYVDAAYKPGMTPEECRRFTTDAITLAMNRDGSSGGVIYLVTITADGVDHRVILGDELPKFYDE
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  This subunit is involved in antigen processing to generate class I binding peptides.
What are the official names of this protein?
Proteasome subunit beta type-9, Low molecular mass protein 2, Macropain chain 7, Multicatalytic endopeptidase complex chain 7, Proteasome chain 7, Proteasome subunit beta-1i, Really interesting new gene 12 protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ARAB_SALAR
Sequence: MAIAIGLDFGSDSVRALAVDCATGGEIATSVEWYPRWQEGRYCDGPNNQFRHHPRDYMESMEIALKRVLAELSAAQRANVIGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEADEITRLCHMPGKVDYSRYIGGVYSSEWFWAKILHITREDSAVAQAAVSWVELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPCINRHLRYPLFSETFTADLPVGTLCAEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNTLVKVIGTSTCDILIADKQSVGDRAVKGICGQVDGSVVPNFIGLEAGQSAFGDIYAWFGRVLSWPLAQLAARHPELKDQINASQKQLLPALTDAWAKNPSLAHLPVVLDWFNGRRTPNANQRLKGIITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQVCCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPAAQQNMASAVERTLHPRPEQAQRFEQLYRRYQQWALSAEQHYLTTATPALTTPVNQAILTH
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: IOLE_LACCA
Sequence: MTIELGIAPIGWTNDDMPELGKEVTFEQAIDEMTLAGYKGTEVGNKYPKDPKTLKHFLDLRHLKIASAWFSAFLTTKPYEETEAAFIKHRDFLHAMGAKVIVVAEQGHSVQGLLDKSVFDDKPHFTDDEWERLATGLERLGDRAREVGMQIVYHHHMGTGVQTTAEIDRLMTMTDPDKVSLLFDTGHLVLSGEDPLTIFNRYQDRIKHIHFKDVRQQQADEEHKDHLSFLAGVKNGMFTVPGDGMIDFKPIWEAIQESGYDGWIIVEAEQDPAKANPFEYALKAKKYLDATMNIPQSA
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.