PharMolix/UniProtQA huggingface dataset:
Protein: LYSM6_ARTBC
Sequence: MIPRNLISGLFLLPFVVAELNIYGYLDLKTLADGFHTTTACIAALNQTVDCDARTAVAAAVADTYYWTLDNVTTLCTSQCQQSLTSWTSAVDAACGNRPIVEDGIVKLASSTPLTYKEGFDLVCLKSGDSWCMIESQEWEGSDILKYPTDYCSTGDPEYDGPECFEKGFDQLAIEAGDERMTSLYEKDLLCSDCFLKVFRQRLLSPFLLKGGYTSYLVEQFQDMQSYCSTSMPYATSTSEVFMGTATRTMPTGSPPPTTTCGGPTIQPTDPPLSCEAITDKYNVTTGDSHSDLHGEFSLASKPRFLKANAIDRQHEPIEKLDHAICYAGTSEPPGGSYESQPPVHQPTGASEYYTTAIPPAPTSTGTTPSCGRYYEVVAGDQCNTIALHFGITVDAFLSLNTQIDERCSNLWIAYAYCVAPVDIVDQPMTIVDQDIATQGNVLPATELPSPRMGRVVLNIMIGSVVTQLLENAALSMDIAGVRRTSAQQGIVIRVPVIQTLAKRVLTVRADQALQETKHVPALNLAHVATWRDIVEMEPTTAHPGDAILERAKGPRIHSIALYVTVLYLDLWI
What is the function of this protein?
Might have a role in sequestration of chitin oligosaccharides (breakdown products of fungal cell walls that are released during invasion and act as triggers of host immunity) to dampen host defense.
What are the official names of this protein?
LysM domain-containing protein ARB_01155/01156.
What are the subcellular locations of this protein?
Secreted.
Protein: ACT5_SOLTU
Sequence: AGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVSNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDHLMKILTERGYSFTTTAEREIVRDVKEKLSYIALDYEQEIETAKTSSSVEKSYELPDGQVITIGAERFRCPEVLFQPSMIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQ
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-66.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LMO3_MOUSE
Sequence: MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
What are the official names of this protein?
LIM domain only protein 3, LMO-3, Neuronal-specific transcription factor DAT1.
Protein: DAPF_SHESR
Sequence: MIQFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLADRNFGVGFDQLLLVEPPYDPDLDFHYRIFNADGGEVENCGNGARCFARFVRNKGLTNKNKIRVSTSAGKMTLRLERDGTVTVNMGVPVLDPSQIPFKAKKAEKTYLLQTSQQTFLCGAASMGNPHCVLDVEDVANANVAEIGALLTKHERFPRGVNVGFMQVVNSGHIKLRVYERGAAETLACGTGACAAVVVGQIQGKLDQQVRVDLPGGTLTINWEGEGKPLWMTGPAQHVYDGQIQL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WR451_ORYSJ
Sequence: MTSSMSPAPAPAYAQVMEDMEKGKELAAQLQGLLRDSPEAGRFVDQILHTFSRAMRALDKAAVSAAGGEGSEVQSEVTCGGGASAGGKRKAPAADRKANCRRRTQQSSGNSVVVKNLDDGQAWRKYGQKEIQNSKHPKAYFRCTHKYDQLCTAQRQVQRCDDDPASYRVTYIGEHTCRDPATAPIIAAHVIHQVAAGDNDDGCGGLQAGSRLISFVAAPAAPVDAAAAPTTSTITTVTAPGPLLQPLKVEGGVGSSDQEEVLSSLTPGSSAARGGGGGGGVAGPFGPDQGDVTSSLHWSYDAVAGMEFFKNDEVVFDLDDIMGLSF
What is the function of this protein?
Transcriptional activator involved in defense responses against pathogens (PubMed:17601827, PubMed:19700558, PubMed:21726399).  Acts as positive regulator of defense responses against the rice blast fungus Magnaporthe oryzae (PubMed:17601827, PubMed:19700558, PubMed:21726399).  Acts through W-boxes, which are cis-elements that are enriched in the promoters of several defense-related genes (PubMed:17601827).  Plays an important role in the benzothiadiazole-induced disease resistance by mediating salicylic acid (SA) defense signaling pathway, independently of the disease resistance gene NPR1/NH1 (PubMed:17601827, PubMed:21726399).  Acts as negative regulator of defense responses against the bacterial blight Xanthomonas oryzae pv oryzae (Xoo) and the bacterial streak Xanthomonas oryzae pv oryzicola (Xoc) (PubMed:19700558).  Acts downstream of abscisic acid (ABA) signaling in response to the rice blast fungus (PubMed:20459318).  ABA is a negative regulator of defense responses that interacts antagonistically with salicylic acid (SA) signaling pathway (PubMed:20459318).  Acts as negative regulator of ABA signaling that suppresses growth of seedlings (PubMed:21725029).  Does not seem to be involved in the regulation of salt stress response (PubMed:21725029).  Acts as negative regulator of cold stress response (PubMed:21725029).  Acts as negative regulator of drought stress response (PubMed:21725029).
What are the official names of this protein?
Transcription factor WRKY45-1, OsWRKY45-1, OsWRKY45, WRKY transcription factor 45-2.
What is the protein family that this protein belongs to?
Belongs to the WRKY group III family.
What are the subcellular locations of this protein?
Nucleus.
Protein: USB1_RAT
Sequence: MNAAPLVGYSSSGSEDEAEAVAAGRSKPGSGLHRCGQNPLPSQRFPVPDSVLNMFPSTEEGPEDDSARHGGRIRTFPHERGNWATHIYIPYEANEEFQDLLDVLLPRAQMFAPRLVQMEEFHLSLSQSVVLRHHWILPFVQVLKDRMASFQRFFFTANRVKIYTNQEKTRTFIGLEVSSGHAQFLDMVSEVDRVMKEFDLTTFYQDPSFHVSLAWCVGDARLQLEGQCQQELQEIVDEFEDSEMLLRVLAEQVRCKSGNKFFSMPLK
What is the function of this protein?
3'-5' RNA exonuclease that trims the 3' end of oligo(U) and oligo(A) tracts of the pre-U6 small nuclear RNA (snRNA) molecule, leading to the formation of a mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.  Participates in the U6 snRNA 3' end processing that prevents U6 snRNA degradation.  In addition also removes uridines from the 3' end of U6atac snRNA and possibly the vault RNA VTRNA1-1.
What are the official names of this protein?
U6 snRNA phosphodiesterase 1, 3'-5' RNA exonuclease USB1.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. USB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADA17_HUMAN
Sequence: MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC
What is the function of this protein?
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form (PubMed:9034191).  Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (PubMed:20592283).  Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein (PubMed:12441351).  Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT) (PubMed:24226769).  Plays a role in the proteolytic processing of ACE2 (PubMed:24227843).  Plays a role in hemostasis through shedding of GP1BA, the platelet glycoprotein Ib alpha chain (By similarity).  Mediates the proteolytic cleavage of LAG3, leading to release the secreted form of LAG3 (By similarity).  Mediates the proteolytic cleavage of IL6R, leading to the release of secreted form of IL6R (PubMed:26876177, PubMed:28060820).  Mediates the proteolytic cleavage and shedding of FCGR3A upon NK cell stimulation, a mechanism that allows for increased NK cell motility and detachment from opsonized target cells.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LV1A_MOUSE
Sequence: MAWISLILSLLALSSGGAISQAVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGVPARFSGSLIGDKAALTITGAQTEDEAIYFCALWYSNH
What are the official names of this protein?
Ig lambda-1 chain V region.
Protein: VP9_APRVF
Sequence: MNSQKVQALTTVSKLSPIDKVVKGRNIPFSMPGDRVIMLKISSLFKFGREDKESDSKFDLVPTDCGICMVKTQLNQDEQKRTTFNDGKVIEIITYEQMKDILPMIKQAIHEFYSWRRGLMDTSTLEARNEWKPVSQLDFRRCNSNLIFYISILILSEYIIEIPIEYLTVSYGGYNFNNIRTGEWFNTDDFNNYQKVIKSGDVCDLFLINDTGEYKYINAITHVTKTNMIFSFNMQVSRPPQLNTTMKVRQTLSENKKQKSSSTSPETDSDMSEFFGDN
What are the official names of this protein?
Uncharacterized protein VP9.
Protein: MCA1_CANAL
Sequence: MFPGQGRHTYGGQQSNYSNQQQGYDQGYNQGYGQAYGQEYNQGYDRPSGPPPGQGQYNRPSGPPPGPPPGQGQYNRPSGPPPSQQGQYNRPSGPPPGQYGNNQTRGSGNEQNYGNMHGSGHYSRPPTDSQSFGVENYNYQYSNCSGRKKALLIGINYIGTKNELRGPINDVNNVEQFLLANGYSSDNIVKLTDDQRVQRAIPTRQNILDAIQWLVKDARPNDALFFHYSGHGGQTEDQPDEYGNYDEDDGYDEVIYPLDFETNGFIIDDLLHTMMVKTLPQGCRLTALFDSCHSGSVLDLPYMYSTKGVLKEPNVMKEAGAGLLQSAMAYATGDRSRMLSGLGGVVKTFMNQGKAEKANEYSKQTNTAPCDAISLSGCKDDQTSADSKENGTATGAMSYAFLTVMSQNPNQSYLSLLQNMREILSAKYSQKPQLSASHPIDTNLQFIF
What is the function of this protein?
Involved in cell death (apoptosis).
What are the official names of this protein?
Metacaspase-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: ACYP_CALS4
Sequence: MKKTVHLRITGHVQGVGLRYSVYQKATSLGITGYAENLYDGSVEVVAEGDEESIKELIHFIKTGLRWARVDNVEERWLEYKGQYKDFRIY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: PRMA_SHIBS
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_CHLPN
Sequence: MEKFSDAVSEALEKAFELAKSSKHTYVTENHLLLALLENTESLFYLVIKDIHGNPGLLNTAVKDALSREPTVVEGEVDPKPSPGLQTLLRDAKQEAKTLGDEYISGDHLLLAFWSSNKEPFNSWKQTTKVSFKDLKNLITKIRRGNRMDSPSAESNFQGLEKYCKNLTALAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPMLIGEPGVGKTAIAEGLALRLIQGDVPESLKGKQLYVLDMGALIAGAKYRGEFEERLKSVLKDVESGDGEHIIFIDEVHTLVGAGATDGAMDAANLLKPALARGTLHCIGATTLNEYQKYIEKDAALERRFQPIFVTEPSLEDAVFILRGLREKYEIFHGVRITEGALNAAVLLSYRYIPDRFLPDKAIDLIDEAASLIRMQIGSLPLPIDEKERELAALIVKQEAIKREQSPSYQEEADAMQKSIDALREELASLRLGWDEEKKLISGLKEKKNSLESMKFSEEEAERVADYNRVAELRYSLIPQLEEEIKQDEASLNQRDNRLLQEEVDERLIAQVVANWTGIPVQKMLEGEAEKLLILEESLEERVVGQPFAVSAVSDSIRAARVGLNDPQRPLGVFLFLGPTGVGKTELAKALADLLFNKEEAMVRFDMSEYMEKHSISKLIGSSPGYVGYEEGGSLSEALRRRPYSVVLFDEIEKADKEVLNILLQVFDDGILTDGKKRKVNCKNALFIMTSNIGSPELADYCSKKGSELTKEAILSVVSPVLKRYLSPEFMNRIDEILPFVPLTKEDIVKIVGIQMRRIAQRLKARRINLSWDDSVILFLSEQGYDSAFGARPLKRLIQQKVVILLSKALLKGDIKPDTSIELTMAKEVLVFKKVETPS
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_PROMS
Sequence: MQDHNSTNESFDVIVIGGGHAGCEAAITTAKLGFSTALFTINLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADETAIQKRILNASRGPAVWALRAQTDKREYSKKMIEILQNTDNLSLKEAMITELDIAKTEQIGLNSKKILKKRIKGVKTFFGSYYSARSVIITAGTFLEGRIWIGNKSMSAGRSGEQAAQGLTQNLHEIGIKTERLKTGTPARVDKRSIIFDELDVQPSTAVDKYFSFDPDIKNNMPQVSCHITRTTTKTHQLIRDNLHLTPIYGGFIDSKGPRYCPSIEDKIVKFANKESHQIFLEPEGINTPEIYVQGFSTGLPENIQLELLRTLPGLGECKMLRPAYAVEYDYIPATQLQTSLETKEIEYLFSAGQINGTTGYEEAAAQGLVAGVNATRKLNKKDPIIFSRESSYIGTMINDLITKDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGYQIGLINEKRWSAYQEKMNLLEEEKFRLNNTRLKNTDEISKKIELETGSKIKGSTTLKELLKRPNFHYSDLIKYNLNERNLGSSIQEGVEIDIKYEGYLKRQKNNIEQINRQSCKSLPQEINYEKIETLSLEARENLNKIKPKNFGDASKIPGVSKADLTALLVWLKIREIKKEKANIFVEKKLSS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACL5_ARATH
Sequence: MGEAVEVMFGNGFPEIHKATSPTQTLHSNQQDCHWYEETIDDDLKWSFALNSVLHQGTSEYQDIALLDTKRFGKVLVIDGKMQSAERDEFIYHECLIHPALLFHPNPKTVFIMGGGEGSAAREILKHTTIEKVVMCDIDQEVVDFCRRFLTVNSDAFCNKKLELVIKDAKAELEKREEKFDIIVGDLADPVEGGPCYQLYTKSFYQNILKPKLSPNGIFVTQAGPAGIFTHKEVFTSIYNTMKQVFKYVKAYTAHVPSFADTWGWVMASDHEFDVEVDEMDRRIEERVNGELMYLNAPSFVSAATLNKTISLALEKETEVYSEENARFIHGHGVAYRHI
What is the function of this protein?
Required for correct xylem specification through regulation of the lifetime of the xylem elements.  Prevents premature death of the xylem vessel elements.
What are the official names of this protein?
Thermospermine synthase ACAULIS5.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
Protein: RAD5_CANGA
Sequence: MDQNANQKKRFFKDELESSIETTLTDKSSFLFEPQVDAIQEENANDPEEQIAQGTQESPFIEQLRAVLPTIRLEVALALEEKYRDIDDGLDLAISEYFDQYQTGNDDAPPSSLELQHSQEVLTVPDNEEKDTDLQLVSVKRKREDDFMQSSQSKKPQRANSSWKKFVGSLQVTVMVTRPTMRPVPYGTPLIFKRSNNNVPLKKIYEQLNKKKTGLAAFVKIYSANDEREIGRVPEDIARIVFPLLHRNEVHFKLTMIYPGDKRLSIGDNIIIQMDSFLTSTLFNRKENPTFSTQNGNGRERFGAIVETEQELEERNIRMGLIMLFDKIKLRPVKDEAKFLEKLKQDGDDNEIVDLEDDESFGNFLSQEPLNDELPTQHQEDTMNINQLTSFYKATQSSKQLNSLIPTTPPPELVKVELRKYQKQGLTWMLRREGISIGHDNEDKSEDDTTLLNPLWRQFQWPRNMSWHNQSTGSENDNSNPKLIFFYGNLHTGEFSLERPTMNSFKNGGILSDEMGLGKTISALSLVLMRPKDEHTTSQSLFHQESSNLSSDDVIEIKEPERSYAYKTTLIIVPMSLLTQWRDEFDKVNNNAGLTCELYYGGNVSSLKSLLIKRKNPPTVVLTTYGIVQNEWTKLSKDGTNIRSLGRTSGIFSIEFFRIILDEGHTIRNKSTITSKAVLELSSKYRWILTGTPIINRLDDLYSLVKFLKLEPWSQIGYWKQFITNPFEERNFKQAFDVVNAIMEPVLLRRTKQMKDTDGNPLVQLPPKEIVIEKLQLSKKQKLIYEEFLQRAEKTFRSGLQSGDLLKKYSTILVHILRLRQVCCDSNLIGTLDENDEDLSSGNNKLITESVDVKTLIPDTEEEEDEVPPFENDELDKLIESVEAKFIDSNQLIPVECSICTAEPIESSSAVVTECEHVFCKECLEEYGNFQKEKSLQQKCPNCRRDINLNRCLAFEKGSDGILKLIHFDRKERPAKLNALIRHLQQLQDSSAGEQVVVFSQFSSYLDILESQLNEVYSSNKLKVYKFDGRLSLKERTAVLEDFKVKDYAVQKVLLLSLKAGGVGLNLTCASYAFMMDPWWSPSMEDQAIDRIHRIGQTNSVKVIRFVIDGSIEEKMLRIQDRKRTLGEAMDTDEDERRKRRIEEIQMLFES
What is the function of this protein?
Probable helicase, member of the UBC2/RAD6 epistasis group.  Functions with DNA repair protein RAD18 in error-free postreplication DNA repair.  Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats.  Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity).
What are the official names of this protein?
DNA repair protein RAD5.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HIS5_LEIXX
Sequence: MSRPVVVFEYGSGNVHSAVKALEAAGADVELTRDRRRAQEADGLVVPGVGAFAAVVDRLRAAHGDEIIERRLAGGRPVLGICVGMQVMFERGTEHGQETAGLGEWPGAVEPLCAGVVPHVGWNAVEAPADSVLFDGVWDERFYFVHSYAAQHWTLEATGPFPKPRVSWAEHGSRFVAAVENGPLSATQFHPEKSGSAGLRLLANWIGSL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHPS_STRPQ
Sequence: MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQMIADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARAALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRAQAALDAGVPKNNIWIDPGFGFAKSVQQNTELLKRLDRVCQLGYPVLFGISRKRVVDALLGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: RK16_NICTO
Sequence: MLSPKRTRFRKQHRGRMKGISHRGNHISFGKYALQALEPAWITSRQIEAGRRAMTRNARRGGKIWVRIFPDKPVTLRPAETRMGSGKGSPEYWVAVVKPGRILYEMGGVTENIARRAISLAASKMPIQTQFIIS
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS4_YERPY
Sequence: MIIPALDLIEGKVVRLHQGDYGQQRDYGNHPLPRLQDYQQQGAQVLHLVDLTGAKDPAARQIPLLRELLAGVDVPVQVGGGIRNEQDVVALLEAGAARVVVGSTAVKQPEMVQQWFERYGAEAIVLALDVRINEAGCKHVAISGWQENSDATLEQIVEQYLPYGLKHVLCTDISRDGTLSGSNVELYQEVCQRYPQVAFQASGGIGCLDDIARLRGSGVQGVIVGRALLDGKFNVKEAIACWQNV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH13_CHICK
Sequence: MMWRDALSLVEEEDPHMKVSLGSSDMGVSAHLQSSKTGTTRFFTSNTHSSVVLQGFDQLRVEGLLCDVTLVPGDGDEVFPVHRAMMASASDYFKAMFTGGMKEQDLMCIKLHGVNKIGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLENCVEVGRIANTYNLTEVDKYVNNFILKNFPALLSTGEFVKLPFERLAFVLSSNSLKHCTELELFKAACRWLRFEEPRMEYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSERTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDEKAHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRNAAGELATVECYNPRMNEWSYVAKMNEPHYGHAGTVYGGLMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSTTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEDNTGSPSRESPLSAP
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis.  The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis (By similarity).
What are the official names of this protein?
Kelch-like protein 13.
Protein: LPXK_VIBCH
Sequence: MVIEKIWFHRHPLGYLLWPLLWPFSVLFGVISRSRRKAYQTGDKPSYRAPLPVVVVGNITAGGNGKTPVVVWLVETLQNLGYRPGVVSRGYGAKAPSYPLVVNEQTPAQHCGDEPKLIFQRTKAPVAVDPVRSQAVKALLEHGVNVIVTDDGLQHYALQRDIEIAVVDGVRRFGNQELIPLGPLREPVSRLDEVDFIITNGGVAKANEIAMRLQPTDAVNLKTGERCAVSKLTRLCAMAGIGHPSRFFNTLRELNADLVHCQGFADHQAFDAAQLNQLAQQGAHLIMTEKDAVKCAEFAQPNWWYLPVSAQFAPEAEQRIVDKIKEVMEPYGSPSA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RL27_CHLSY
Sequence: MAHKKGVGSSRNGRDSNPKMRGVKRFGGEHVRAGNIIVRQCGTKIKPGENVGVGRDWTLYALVDGVVQFGHYSRTQKMVSVIPVTAAETAH
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SCX28_HOTTS
Sequence: GVRDAYIADDKNCVYTCGSNSYCNTECTKNGAESGYCQWFGRWGNGCWCIKLPDKVPIRIPGKCR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This toxin inhibits the inactivation of activated TTX-sensitive sodium channels (Nav).
What are the official names of this protein?
Alpha-toxin Bs-Tx28.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPP_FRATH
Sequence: MITNNLVPTVIEKTAGGERAFDIYSRLLKERIVFLNGEVNDHSANLVIAQLLFLESEDPDKDIYFYINSPGGMVTAGMGVYDTMQFIKPDVSTICIGLAASMGSLLLAGGAKGKRYSLPSSQIMIHQPLGGFRGQASDIEIHAKNILRIKDRLNKVLAHHTGQDLETIVKDTDRDNFMMADEAKAYGLIDHVIESREAIIK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDPKX_ARATH
Sequence: MGNCLAKKYGLVMKPQQNGERSVEIENRRRSTHQDPSKISTGTNQPPPWRNPAKHSGAAAILEKPYEDVKLFYTLSKELGRGQFGVTYLCTEKSTGKRFACKSISKKKLVTKGDKEDMRREIQIMQHLSGQPNIVEFKGAYEDEKAVNLVMELCAGGELFDRILAKGHYSERAAASVCRQIVNVVNICHFMGVMHRDLKPENFLLSSKDEKALIKATDFGLSVFIEEGRVYKDIVGSAYYVAPEVLKRRYGKEIDIWSAGIILYILLSGVPPFWAETEKGIFDAILEGEIDFESQPWPSISNSAKDLVRRMLTQDPKRRISAAEVLKHPWLREGGEASDKPIDSAVLSRMKQFRAMNKLKKLALKVIAENIDTEEIQGLKAMFANIDTDNSGTITYEELKEGLAKLGSRLTEAEVKQLMDAADVDGNGSIDYIEFITATMHRHRLESNENVYKAFQHFDKDGSGYITTDELEAALKEYGMGDDATIKEILSDVDADNDGRINYDEFCAMMRSGNPQQPRLF
What is the function of this protein?
Ca(2+)-dependent protein kinase (PubMed:26662273).  Negative regulator of stomatal closure and slow anion currents (PubMed:26662273).  Unable to phosphorylate THI1 in vitro, but the kinase activity is essential for the stomatal closure regulation (PubMed:26662273).  Phosphorylates FD (PubMed:25661797).  May play a role in signal transduction pathways that involve calcium as a second messenger (Probable).
What are the official names of this protein?
Calcium-dependent protein kinase 33.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Nucleus. Cytoplasm.