PharMolix/UniProtQA huggingface dataset:
Protein: PGK_STRA5
Sequence: MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGAKLEEAINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAFAGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4138_GEOUR
Sequence: MSGGIKQWPEDERPREKLLKRGAKALSDAELLALIIGTGDSSSGRSALDIGREMLQDFGGLRNLAHATASEICRIKGAGPAKAACIKAALELANRYGARRFESLERFTSPSQVFEHFHHEFRDHRKEYFLTLLLDGKNRILKRVQISEGSLNQSIVHPREVFNQAVRESAAAIILVHNHPTGDPTPSREDIDITRRLREAGDLLGIKVLDHIIIGDGSFLSFVDRGMM
What are the official names of this protein?
UPF0758 protein Gura_4138.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: HPRT_METPE
Sequence: MLEKLVTSLETCPMVQRNGYNYFIHPISDGVPIVEPELLREIGCAMVKMLDLDKVDKIVVAEAMGIHIGTVLSLMTGIPMNIVRKREYKLPGEVAVHQTTGYSKGELYLNGLFAGDRVVIIDDVISTGGTARALLSALGQIGVDVVDICVVIQRGNPDIGRDYKSLTKIEVNERVHVIDKHC
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
What are the official names of this protein?
Hypoxanthine/guanine phosphoribosyltransferase, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_THEP3
Sequence: MVITNPIVYGKFIKRINRFEAYVELNSGEKTLVHVPNTGRCKEIFVPGAEVILEVRDRQGRKTPYELAFAYKGKRLISIDSQVPNKVVLESIKMGLIEEFKGYDIVEKEKTFGNSKFDIKLTKGKEICYVEVKGVTLEVEGVAKFPDAPTERGRKHLKELIKVKKEGMRAAVIFLIQMDDIKYFTPNDEQDPEFGKFLREAVGKGVEAYAYTCDVGENYVFLKDRVEVVL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: PHLP_RAT
Sequence: MTTLDDKLLGEKLQYYYSTSEDEDSDHEDKDRGRGAPASSSTPAEAELAGEGISVNTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMSCRSHLDEEEEQQKQKDLQEKISGKMTLKECGMMDKNLDDEEFLQQYRKQRMDEMRQQLHKGPQFKQVLEIPSGEGFLDMIDKEQKSTLIMVHIYEDGVPGTEAMNGCMICLAAEYPTVKFCRVRSSVIGASSRFTRNALPALLIYKAGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID
What is the function of this protein?
Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers.  Acts also as a positive regulator of hedgehog signaling and regulates ciliary function.
What are the official names of this protein?
Phosducin-like protein, PHLP.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: RPC3_ASHGO
Sequence: MNGSMGAAGGQVENERAAEVPVSTLEMRTLSPETFLYTEVARSHLGERAGRVIELLLNKGRLSVSELVHLAPELGSKSVRTVLVSLIQLRCVQYLEETTVSGRKITYYYFNEDGFQLMLYAGDIVAAVESQFEADDAKEIAAQIVQNVLALGSLTTKDYMQSLASDVSVNDVASMFVKLVELGFLVPLSNVHYMPLADLWDVLYKKEYNAIPKNSTLSDAKKRAETKAKTKVQFNTLLKNVEMSNVLMTDMQTSMRRVQDNLPLTFNFGRYMKHRRSRQLVQFARSRVGSVPAMIYKVALKITEQCARALSDPLCETGLMQELEEQLAIQEDMALDDEKLPGVTFNAVDISRNLPNNIDLRGTLTSMQRRSQERSTHQGQSHKRLKAEDGMAVAVNHLATVEEEAEGDELLHGSDDDMDMFFDEGDSDPKSVSLINGHLKLLSTGSVPFLIESRPGLFYVPYSKLMPILKEAVYDAIIASTLGPSAHRILRCVRDNSLVSEKVINNTALMREKDIRSVIATLVKYNAVDILEVPRTADRAASRAVFLFKINEKHAYDFMKQNLAWNIANSIHKTEILKEENFTLLSKAQRDDVKGREAELLLPSELNQLKMVNERELNGHARKIRLLSMWEVFKML
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC3, RNA polymerase III subunit C3.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABA_HAHCH
Sequence: MHAIAENHGVKASYTKEELQACGQGRLFGEGAAKLPVDQMLMVDRVSQISAEGGAYGHGIVRAQLDINPDLWFFKCHFVGDPVMPGCLGLDAMWQLVGFFLAWKGHKGLGRALGVGEVKFTGQVLPSAKSVEYVLDIKRVIARKLIMALADGTVYVDGKAIYTAKDLRVGLFDPAAMSGAEIK
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTC_ECO45
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRARLPELQSTIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRGERSETAQQIIDRLRKKLAKEPGANLFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQEDNGAEMNLIYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALQLFNAPFSLIALIGIMLLIGIVKKNAIMMVYFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQAVTE
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS10_LACDA
Sequence: MANEKIRIRLKSYEHSILDESGAKIVDTAKRTGAEISGPVPLPTERTLFTVLRSPHKNKDSREQFEMRTHKRLIDILNPTPKTVDSLMKLDLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: TMCO4_CAEEL
Sequence: MSKCATPTPSTSSNSSDEAKRSPQPMSRGFPQRNMSTTSSNGSNSPRHRSLETPIVLQPATRFALANLTTTVLRLDFWDDNDPNSIFFCKSTFNIVTQCLDLPEKVIKTVKTHLEGEEDLTDIAPMIMSVREDPVYKTEGSTPFLASLLVAFVNQGNYDSRYRVFLRHLTTLLGVVWTEFEDVEDSLASTLLEEQFVESEHSRTVREKTARNKKIKRYLMIGAAGGVGGVLIGLTGGLAAPLVAASAGMLIGGGAVAGLATTAGAAVLGTTMGVAGAGFTGYKMKKRVGAIEEFSVETLSEGVSLSCSLVVSGWIESDTSPDQAFVHQWRHLRHTKEQYTLRYESNYLMELGNAIEYLMSFAVSVAIQQTLLETALAGLVSAVAWPVALMSVSSVLDNPWNVCVSRAAEVGEQLAEVLLSRSHGKRPITLIGFSLGARVIFHCLLTMSKRSESVGIIEDVILLGAPVTASPKEWSKVCTVVSGRVINGYCETDWLLRFLYRTMSAQFRIAGTGPIDNRNSKKIYNYNLSHIVKGHMDYSKRLTEVLNAVGVKVGPHSEDSVVDLTQLEGPHEATGQAEEAINYQSTGEEEEHPIVHPINLENIHEVKVLDSPHKNEF
What are the official names of this protein?
Uncharacterized membrane protein F35D11.3.
What is the protein family that this protein belongs to?
Belongs to the TMCO4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CCMA_VIBVY
Sequence: MLEVSNLTAIRDERVLFENLQFEIKPGELVQIEGRNGTGKTTLLRIVTGLGDRDEGSIKWKGEAIEKSRDQFHQDLLFLGHQTGVKRELTAFENLRFYQSIHNSDSSSERIFHALTQVGLAGREDVPVAQLSAGQQRRVALARLWLSHQILWILDEPLTAIDKQGVKVLESLFSNHVDNGGIVILTTHQDMFADSPKLRKIKLGD
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: STMN1_RAT
Sequence: MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHVEEVRKNKESKDPADETEAD
What is the function of this protein?
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules.  Prevents assembly and promotes disassembly of microtubules (By similarity).  Its phosphorylation at Ser-16 may be required for axon formation during neurogenesis.  Involved in the control of the learned and innate fear (By similarity).
What are the official names of this protein?
Stathmin, Leukemia-associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein p19, pp19, Pr22 protein, Prosolin, pp17.
What is the protein family that this protein belongs to?
Belongs to the stathmin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CYSA_VIBVU
Sequence: MSIQVSGLCKHFGQFTALNNVSIEFPSGGLVALLGPSGCGKTSLLRVIAGLERPDSGTVAIQNRDVSGLDIRERQVGFVFQHYALFRHMTIFENVAFGLRAKPKARRPNEATIKQKVNRLLQLVQLDWLADRYPAQLSGGQRQRVALARALAIEPQVLLLDEPFGALDAKVRKELRRWLRKLHDELHITSLFVTHDQEEALEVADHIVVMNKGQIEQIGTPEEIYRTPRTEFVYQFVGSSNRLYLEDSNGLSFTPSDVVSTHGKQAKRIYCRPHDFAVNTQHRPDAIPVAVARKLALGNMVRLEAYSLDNQQLVEVELSNHDPVLDEIQAKRHLWLTPKTVSQFA
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATRIP_MOUSE
Sequence: MAGTPAPNSHRKQSGGLEPFPGLSRSIENPPSKRARSFSETTVPDPEDPFGEHAEFTADDLEELDILASQALSQCPVAPRNLSSAHKVRRLDGLPNSPIRKSREDIPVKDNFELEVLQIQYKELKEKLKAMEEEILIKNGEIKILRDSLRQTESVLEEQKRSHFLLEQEKTQALSEKEKEFSRKLQSLQSELQFKDAEMNELRTKSQSNGRTNKPAAPSVSHVSPRKGSSVVLKSEACSPHVGKTTFPTKESFSANTPLFHPCQTEAGHRFLVGQEVSDNKNHSLGGSLMKQDVQQRILADGWMQRKDAQGSILINLLLKQPLVPGSSLGLCHLLSSCPEVPTGTLLQPPGLSTLPGTSGLRTISSSDGPFSPSALREAQNLAFTGLNLVARTESSHDGDMAGRRVFPLHQLPGAVHLLPLVQFFVGLHCQALQDLAPAKKSGVPGDSATHTSCMSSGVEASPEDSIHGLESFSVASLSVLQNLVCHSGAVVCLLLSGMGTEAAAREGNLVQTCADTTSASREDAHDQDQHPLLKMLLQLMASSSAASGHFQASVLGLCLKVLVKLAENASSDLLPRFSCVFPVLPQCLGSALPLPCVLLAVELLSVLLDHDSLAWQLCSHPEGCLLLRLYMYITSRPDRTASETQWLQLEQEVVWLLAKLSVQSPAPAGIGSDCHCNVEAVRALTVMLHRQWLTVRRAGGPRTHQQKQTIRCLRDTVLLLHSLSQKDKLFTVHCVEVLHQYDQVMPGVSMLIRALPDVTDCEEAALDDLCAAETDLEDSEMDCN
What is the function of this protein?
Required for checkpoint signaling after DNA damage.  Required for ATR expression, possibly by stabilizing the protein (By similarity).
What are the official names of this protein?
ATR-interacting protein, ATM and Rad3-related-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the ATRIP family.
What are the subcellular locations of this protein?
Nucleus. Note=Redistributes to discrete nuclear foci upon DNA damage. Interacts with CEP164 (via N- terminus) (By similarity).
Protein: Y706_YERE8
Sequence: MDYEFLRDLTGQVLVRFSMGHEVIGHWLNEEIKGDLAKLDQIEAAAAEVKGSERQWQLDGHEYTLWLDGEEVMVRANQLDIEGDEMEEGMNYYDEESLCLCGLEDFLRVLQGYRNFIISK
What are the official names of this protein?
UPF0231 protein YE0706.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: YCFP_ECOL5
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: VATE_METTP
Sequence: MALDAVVEDILATSKSKVAEINAETEQEVARILSEARERAAEIKSRKEAEAKHDIEALVRREMSSANLELKRAELNVHKEVLEQVRIKFLDAVTNLPKDKNEALIKKLLEPYDLKDMKVYSSKRDQAFVSSLVPNYGGTLDIIGGVVVESKDGSVRFDHSYETLARDIFNAKVKEVSKLLFG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: SYW_VIBPA
Sequence: MSKPIVLSGVQPSGELSIGNYLGALRQWQQMQDDYDCQYCVVDLHAVTVRQDPKALHEATLDALAICLAVGVDPKKSTLFVQSHVPEHAQLGWLLNCYTQMGELSRMTQFKDKSARYANDVNVGLFDYPVLMAADILLYGAHQVPVGSDQKQHLELARDIATRFNNIYSPESPIFTVPEPYIPTVNARVMSLQDATKKMSKSDDNRKNVITLLEEPKSIIKKINKAQTDTETPPSIRHDVENKAGIANLMGLYSAATGMSFEEIEAKYKGVEMYGPFKKDVGEAVVAMLEPIQEEYRRIRADRAFMDEVMKQGAEKASARAAETLKKAYEAVGFVARP
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRPE_BACHK
Sequence: MKYDIIGDIHGCLQEFQNLTEKLGYNWSSGLPIHPDQRKLAFVGDITDRGPHSLRMIEIVWELVIHKKVAYYAPGNHCNKLYRFFLGRNVTIAHGLETTVAEYEALPSHKQNMIKEKFITLYEQSPLYHVLDEKRLLVCHAGIRQDYIGRQDKKVQTFVLYGDITGEKHADGSPVRRDWAKEYKGTTWIVYGHTPVKEPRFVNHTVNIDTGAVFGGKLTGLRYPEMETVSVPSSLPFVPEKFRPIS
What is the function of this protein?
Asymmetrically hydrolyzes Ap4p to yield AMP and ATP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical], Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the PrpE family.
Protein: THI4_EMENI
Sequence: MSPPAAIFEPTVAPTGIKGKVVVPETATIPGDSQTKLLDHFGGKWDNFKFAPIRESQVSRAMTRRYFQDLDRYAESDVVIVGAGSCGLSTAYVLAKARPDLKIAIIEASVSPGGGAWLGGQLFSAMVMRRPAELFLNELGVPYEEDPDMPNYVVVKHASLFTSTLLSKVLSFPNVKLFNATCVEDLVTRPGPNGNAQEVQIAGVVTNWTLVTLHHDDHSCMDPNTINAPVIISTTGHDGPFGAFSAKRLVSMTTIDKLGGMRGLDMNSAEDAIVKNTREVAKGLIIGGMELSEIDGFNRMGPTFGAMVLSGVKAAEEALRVFDDRKRECAE
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRUA_CLOBB
Sequence: MRNIKLIIEFDGTNFCGWQRQIKDRTVQGCLEKAILKITGEKSLTNGSSRTDGGVHAKAMVANFITNSSIPGEKFREALNTKLPDDIAVIKSEEVDMDFHARYSSKGKMYSYTIVNRYEKLSFGKQYVHHVRKELNVEDMKKACECFIGKHDFKAFMSPGSSAKTTVRTIQEFYIEKNEDVIKIFISADGFLYNMVRIIVGTLINIGTGKTKLEDVDNIINDGIRKRSGMCVPPNGLVLEKVFY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: ENO_STAA3
Sequence: MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TRPB_POLNA
Sequence: MYDYHQPDLAGHFGIYGGSFVSETLTHAINELKDAYARYQNDPKFLAEFNYELKHFVGRPSPIYHAARMSREQGGAQIYLKREDLNHTGAHKINNTIGQAMLARRMGKQRIIAETGAGQHGVATATICARYGLECVVYMGSEDVKRQSPNVYRMNLLGATVVPVESGSKTLKDALNEAMRDWVANVDNTFYIIGTVAGPHPYPMMVRDFQSVIGTECLSQMPEMNAGRQPDAVVACVGGGSNAMGIFHPYIAHENTRLIGVEAAGEGLDSGKHSASLQRGLPGVLHGNRTYVLQNDDGQVTETHSISAGLDYPGVGPEHAYLKDIGRAEYVGITDTEALQAFHYLCRTEGIIPALESAHAVAYAMKLAKTMRSDQSILVNLSGRGDKDIGTVADLSGADFYDRPSMRGLGVKGGVATSPESFDASGAKGAGSQS
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: TYRP2_HUMAN
Sequence: MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQCTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCERKKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCSVYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESFALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCNGTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTLVALVGLFVLLAFLQYRRLRKGYTPLMETHLSSKRYTEEA
What is the function of this protein?
Plays a role in melanin biosynthesis (PubMed:33100333).  Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
What are the official names of this protein?
L-dopachrome tautomerase, DCT, DT, L-dopachrome Delta-isomerase, Tyrosinase-related protein 2, TRP-2, TRP2.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Melanosome membrane; Single-pass type I membrane protein. Melanosome. Note=Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.
Protein: SSRP_PSYA2
Sequence: MSKKSKKPENQICANKKARHEYFIEETFEAGLSLQGWEVKAIRAGKMTITEAYIIFRNNEAFLFGAHIQPLLSSSTHVSPDSIRTRKLLLNRREIEKLFGAVNQKGYACVPLSCYWKNSLVKCQIGLALGKKQHDKRKTLKDRDWERDKQRGFKKDLD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SECE_STACT
Sequence: MAEDKKKAPKDSFFKGVISEMEKTSWPTKEEILKYTTIVIVTVVFFLIFFYALDLGIGKLIELIS
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DANCR_HUMAN
Sequence: MAGPVPPHPGLAVRAAALHPAPLRIFPGLAELPDLSRGSAARPALAQSLPGIGCGPRDPPASLPAPRRLSGLCARRRSQASLSAGVARADAPLCSGFRAGHACGTGTQPQPTLSSRSSSLTSAEVQLPQFLAQVDNYRHKPLKLECPVAGISIDLSQLSLQLQ
What are the official names of this protein?
Putative uncharacterized protein DANCR, Anti-differentiation ncRNA protein, Differentiation antagonizing non-protein coding RNA, Small nucleolar RNA host gene protein 13.
Protein: BETA_ECO55
Sequence: MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNALDLDNWAQEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEAMIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRTHAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAELLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGGTGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSPSRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISPGTECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIMPQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPVRAKK
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: YOZW_BACSU
Sequence: MTEIKANSTVMIHVLADETLSSIKREYVEVDRKTEIGEKIIIVDKNDPDDEYENGAI
What are the official names of this protein?
Uncharacterized protein YozW.
Protein: UL88_HHV7J
Sequence: MTAKQIFPVWKDCTLYVNNETATVHEILNSDLSELLQLKTEFVSMTDLCVYITGCINQNISSITIYWHAYSEVIYALTGIIHCEKISIECGIKSTDNNILYEKPKLFLLRENLAPTELRWKSLIKTKTIKSALSPNQNEIFPKIAHKPSILLEIEEAPRFKEMVSCIWKLVAEEATITSKSENDIVKTCKKLAESQRYTLTNGTVLQNFILVHACLFKLGAVNFWEEMNGKLRQRPELMSKSFTGHEECFYNCYYLCTLLNSIYSYKTLLPEIVDNTRSIHVVVKAYYSEHIDVSYKILSYSTNMMNLFSQYLNFTDLLPYINKHIKIDVSASKQDMIKFLNACLGL
What are the official names of this protein?
Protein U59.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U59/UL88 family.