PharMolix/UniProtQA huggingface dataset:
Protein: YBAB_ECO5E
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GLYA_CALMQ
Sequence: MNLSDAINAVNRVKDIINSHNTWRRKETINLIPSENVMSPLAEYFYINDMMGRYAEGTIGNRYYQGVKYVDEIEAYLVDLMSKLFHASYVDVRPISGTVANMAVYLTLAKGGKIAAVPRQCGGHISHDEVGAPGAFGIKVIHLPCDEENFSINVDSAVKVIREEKPQLVILGASLYLFPHPVKELAQVAHENGAYLMHDSAHVLGLIAGGQFPNSLNEGADLMTSSTHKTFPGPQGGVIFTNNESIFKNIQRAVFPQLTSNYHLHRYASTAITAIEMMTFGESYAYQVRLNAKKLAEELSKYGIPVVAEARGFTETHQVVFDASKFGGGAKVAQLLEDGGIIVNKNMLPWDRSAVRPSGIRMGVQEMTRVGMGTQEMAEIAAFMKAILIDGKEPSSVKGEVKEFKAHYTEVKYGFKLSDVGIKCDCLPLNY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_RICTY
Sequence: MDSKVVIYTDGACSGNPGPGGWGALLKFNDASKKIFGYELVTTNNRMEMTAALEALRVLKKSSIVEIYTDSKYLQHGITVWIHNWMKNNWCKNNNEPVKNVDLWQKLYSELSKHTIMWRWVKGHASNSGNIAADKLAVQGRETAMEILKCRG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VINC_DROME
Sequence: MPVFHTKTIESILDPVAQQVSRLVILHEEAEDGNAMPDLSRPVQVVSAAVANLVKVGRDTINSSDDKILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKIIQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCLEQVKTLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDTSELDNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVIDNATEISERCLPQDSYPIRKLADEVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQGRLEQAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQAAGSGPAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRASKTSRMVAAGGACGNKKIAEILLSSAAQVDSLTPQLISAGRIRMNYPGSKAADEHLQNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLINRVLLVAKQEADNSEDPVFTERLNAAANRLERSLPAMVGDAKLVATNIADPAAAAAWKNSFQRLLGDVREVRDAIAPPQPPPLPTSLPPPIPELSALHLSNQNAERAPPRPPLPREGLAPVRPPPPETDDEDEGVFRTMPHANQPILIAARGLHQEVRQWSSKDNEIIAAAKRMAILMARLSELVLSDSRGSKRELIATAKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTVKATMLGAQGSDEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTSNRLQWVRRQPWYQY
What is the function of this protein?
Involved in cell adhesion.  May be involved in the attachment of the actin-based microfilaments to the plasma membrane.
What are the official names of this protein?
Vinculin.
What is the protein family that this protein belongs to?
Belongs to the vinculin/alpha-catenin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Note=Cytoplasmic face of adhesion plaques.
Protein: SLYX_ECOUT
Sequence: MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: CCA_BUCA5
Sequence: MKIYLVGGAVRDSLLNLPVKDKDWVVVGGTEKILLERNFQQVGKDFPVFLHPETHEEYALARKERKSGKGYTGFDTDCNSDVTLEEDLIRRDLTINAIAQDEYGNYIDPFQGKKDIECGLIRHVSESFIEDPLRVLRVARFAATLVHLGFKIAEETMLLMCIIVKKQELSYLTSNRIWNETEKALKTLNPHVYFQVLYECNALHFFFPEMYFLYEKKNFLNRSFFKKFCNKNIILMGLAEISLLNKDIDVRFSYLCQFLSVNQIDRNYSKIFFDSYAASIIHSVCKRFKIPSYIRDIAVLNTGFYFFLNTIHYQSSKNIINLFSKVDAWRKPDRVKKLAFLSNFNFLRNFKSEFFCIKSGCFLEKCFSVVKNVSIKLILKKGFKGYEIKQEITRLRIKKLEFWRIKNIKHRFYL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
Protein: ORF2_VZVD
Sequence: MHVISETLAYGHVPAFIMGSTLVRPSLNATAEENPASETRCLLRVLAGRTVDLPGGGTLHITCTKTYVIIGKYSKPGERLSLARLIGRAMTPGGARTFIILAMKEKRSTTLGYECGTGLHLLAPSMGTFLRTHGLSNRDLCLWRGNIYDMHMQRLMFWENIAQNTTETPCITSTLTCNLTEDSGEAALTTSDRPTLPTLTAQGRPTVSNIRGILKGSPRQQPVCHRVRFAEPTEGVLM
What are the official names of this protein?
Membrane protein 2, Membrane ORF2 protein.
What is the protein family that this protein belongs to?
Belongs to the varicellovirus ORF2 protein family.
What are the subcellular locations of this protein?
Host membrane; Peripheral membrane protein.
Protein: JIP3_DROME
Sequence: MMDNDDALLNNGGPQSGAETVYGTEDNNMVMSEKNEQVVSIVQQLAGSIYQEFERMINRYDEDVVKNLMPLLVNVLECLDASYRINQEQDVEVELLREDNEQLVTQYEREKSARKQSEQKLLEAEDLAEQENKELATRLESVESIVRMLELKHKNSLEHASRLEEREADLKKEYNKLHERYTELFKNHVDYMERTKMLMGSTHSQMSTASERMDVSRARLNPVARSSGPVSYGFASLENSVMLDTETICSVGSQSDDSGPPSLQNELDNLSGTLERGAATDALQQQHHATSPQSPDSSPVVPNVPTNVGRSTTKKEQRSDNNLYQELSFQDNEESEENEIVTGSWVHPGEYASSANDNYFGMGKEVENLIMENNELLATKNALNIVKDDLIVKVDELTGEVEIVREELNAMQQSRTKLRQRISELEDELKKAKEQVKQQNTEQEENDVPLAQRKRFTRVEMAMVLMERNQYKERLMELQEAVRLTEILRASRTVDNLDRKSKQSIWKYFSNLFTPSNRPTERVADGLGGGPMFRHTGGGSPAHSHGSPSRGSGGGDNRLALTSGQPPVHPASAGLANALIMPKDYAEEGSSERISARRREQYRQLRAHVQKEDGRLHAYGWSLPINKASQEANPNRHSGGVPVPVYCNPLAEASPHMKVFCAAGVNLHGGFTKNGQSLIPANSPYAPKSTLKIAEITSPTADQSMEALDRQMARVSLETLEPETQLSSFVWICTSTHAASTVSVVDANQSATVLDAFPICASHLLCIASVQGAMESDYALLEQSEVVKAGEMLQRPGEGTELLGKVEFVRVKPKSDDEQNSNEKQQQEEEEAKEATEKSNEQLPAVSAEEPLGNVEAIKIRQPLPGAPQRLSTDGNQTNNNNNSSSSSNLLFATKSLNPILETKDRDEPAMSSVGPTMWLGAQDGWLYVHSSVGRWHECLHRVLLPDAVLAIVHVEARVVVALANAQLAVFRRQTDGQWDLNSYHLVTLGDRNHSIRCLCVAGERIWAAHRNKIFIVDPVSLNIVHSLDAHPRKESQVRQMAATGAGVWVSIRLDSTLRLYNTHTFEHKQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWIGTSNGVIISVPLAEVQPKSSSDPHGQMPLCCMANAQLSFHGHRDAVKFFVSVPMLQQPNLNGGLTFTNKRPDMLVMCGGEGYIDFRINDNDMENSIQLEPNQTIENRGDKSYLIVWHVSQR
What is the function of this protein?
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK-signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module.  May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.  Syd is required for efficient kinesin-I mediated axonal transport.
What are the official names of this protein?
JNK-interacting protein 3, Protein sunday driver.
What is the protein family that this protein belongs to?
Belongs to the JIP scaffold family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECM33_YEAST
Sequence: MQFKNALTATAILSASALAANSTTSIPSSCSIGTSATATAQADLDKISGCSTIVGNLTITGDLGSAALASIQEIDGSLTIFNSSSLSSFSADSIKKITGDLNMQELIILTSASFGSLQEVDSINMVTLPAISTFSTDLQNANNIIVSDTTLESVEGFSTLKKVNVFNINNNRYLNSFQSSLESVSDSLQFSSNGDNTTLAFDNLVWANNITLRDVNSISFGSLQTVNASLGFINNTLPSLNLTQLSKVGQSLSIVSNDELSKAAFSNLTTVGGGFIIANNTQLKVIDGFNKVQTVGGAIEVTGNFSTLDLSSLKSVRGGANFDSSSSNFSCNALKKLQSNGAIQGDSFVCKNGATSTSVKLSSTSTESSKSSATSSASSSGDASNAQANVSASASSSSSSSKKSKGAAPELVPATSFMGVVAAVGVALL
What is the function of this protein?
Required for proper cell wall integrity and for the correct assembly of the mannoprotein outer layer of the cell wall.  Important for apical bud growth.
What are the official names of this protein?
Cell wall protein ECM33, Extracellular mutant protein 33.
What is the protein family that this protein belongs to?
Belongs to the SPS2 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid- anchor, GPI-anchor. Secreted, cell wall. Note=Identified as GPI-anchored plasma membrane protein (GPI-PMP) as well as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer.
Protein: ORN_ECO57
Sequence: MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDGWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAMDDIRESVAELAYYREHFIKL
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C1GLT_DROME
Sequence: MTANSLLGRSILNEGRSNKRSFVSLIVGLIVGFCLAELFVYSTPERSEFMPYDGHRHGDVNDAHHSHDMMEMSGPEQDVGGHEHVHENSTIAERLYSEVRVLCWIMTNPSNHQKKARHVKRTWGKRCNKLIFMSSAKDDELDAVALPVGEGRNNLWGKTKEAYKYIYEHHINDADWFLKADDDTYTIVENMRYMLYPYSPETPVYFGCKFKPYVKQGYMSGGAGYVLSREAVRRFVVEALPNPKLCKSDNSGAEDVEIGKCLQNVNVLAGDSRDSNGRGRFFPFVPEHHLIPSHTDKKFWYWQYIFYKTDEGLDCCSDNAISFHYVSPNQMYVLDYLIYHLRPYGIINTPDALPNKLAVGELMPEIKEQATESTSDGVSKRSAETKTQ
What is the function of this protein?
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
What are the official names of this protein?
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, Core 1 O-glycan T-synthase, Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1, Core 1 beta1,3-galactosyltransferase 1, C1GalT1, Core 1 beta3-Gal-T1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: UPPP_CAMHC
Sequence: MSIIDAVILGIVEGLTEFLPVSSTGHLILTAGLLNLEQTDTLKCFEVVIQLGSILAVVFTFFERLKRDKQLWIKLIIGFLPTAAIGYLLYSHIKSLFSQNVVVYMLIIWGVIFIVVELLRKKNPPENEILTLDGISYKQAFFIGLSQCFAMVPGTSRSGATIIAGLLSGLNRQTAAAFSFLLAVPTMFAATFYDTYKNREIFAANMDNIQLFLLGGFVAFLVALFAIKMFLKFVSRFDYIPFGIYRILIAFAFMFFVL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VL1_PCPV1
Sequence: MWRPSDNKLYVPPPAPVSKVITTDAYVTRTKIFYHASSSRLLAVGNPYFPIRKGNKTIVPKVSGFQFRVFKIVLPDPNKFALPDTSIFDSTSQRLVWACIGLEVGRGQPLGVGISGHPLLNKFDDVENSASYAVNPGQDNRVNVAMDYKQTQLCLVGCAPPLGEHWGKGTQCSGVSVQDGDCPPLELVTSVIQDGDMVDTGFGAMDFAQLQSNKSDVPLDICTATCKYPDYLQMAADPYGDRLFFSLRKEQMFARHFFNRAGTVGEQIPEDLLVKGTTSRATVSSTIYFNTPSGSLVSSEAQLFNKPYWLHKAQGHNNGICWGNTLFVTVVDTTRSTNMTVCASTTSSPSATYTASEYKQYMRHVEEFDLQFIFQLCSIKLTAEVMAYIHTMNPTVLEEWNFGLSPPPNGTLEDTYRYVQSQAITCQKPTPDKEKQDPYAGLSFWEVNLKEKFSSELDQYPLGRKFLLQTGVQTTSFARAGTKRAASTSSSTPTTRKRVKRK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GLPK_SHIB3
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLGWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEKHDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: FRI2_TOBAC
Sequence: MLLKLAPAFTLLNSHGENLSPMLSTSSQGFVLKNFSTKSRNGLLVVCASKGSNTKPLTGVVFEPFEEVKKELMLVPTVPQVSLARHKYSDQCEAAVNEQINVEYNVSYVYHGMYAYFDRDNVALKGLARFFKESSEEERGHAEKLMEYQNKRGGKVKLQSILMPLSEFDHAEEGDALYAMELALSLAKLTNQKLLNLHAVATRNNDVQLADFVESKYLREQVEAIKMISEYVAQLRRVGKGHGVWHFDQMLLQEEEVVA
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
What are the official names of this protein?
Ferritin-2, chloroplastic, NtFer2.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DCUP_BURM7
Sequence: MAQTLLNDTFLRALLREPTDYTPIWLMRQAGRYLPEYNATRARAGSFLGLAKQPDYATEVTLQPLERFPLDAAILFSDILTIPDAMGLGLDFAAGEGPKFAHPVRTEADVAKLAVPDIGATLGYVTDAVREIRRALTDGEGRQRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKSMAYARPDLMHRILDVNAQAVAAYLNAQIEAGAQAVMIFDTWGGALADGGYQRFSLDYVRRVLAQLKREHDGARVPAIAFTKGGGLWLEELAATGVDAVGLDWTVNLGRARERVAGRVALQGNLDPTILFAPPEAIRAEARAVLDSYGNHPGHVFNLGHGISQFTPPEHVAELVDEVHRHSRAIRSGAGS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDHC3_DICDI
Sequence: MVNNNNKNNKINDRENEENEKNKKKDKIYENKIGINENNNENNNYQNENFIYTSGDSNDTQEGDISEIQEESTNENNKKLKKRKIKKTKSLYFYKCVTGPDKLFFIVTQIFILVPSLFFEIKLVPISLEISKKLEISNYIITLTLLVFIFYNLYKCAFTNPGIITRNNIEESKKDKIKLTKLQATKKALKKFITSGMDEIANDDPISSSSDFSDSDDDDQDEQGGSSSARNSFENSGDFIVEMEQPTNSNNNNSNNNNNNNKNRNRNNNNNNNNNNNNKNQSKYKEIQIGDSDFKYKCKFCITCGLYREPRSFHCSTCNNCVENFDHHCVWIGNCIGRRNYREFFYFITTTLIYALYLLSMSIVFLNQIVNTTESPANKINNNNINSNSSNHNSSNDLNEKFEKSINNILYALRTTSGGLCIFIIIFGFIMSLLLGFLVSYHIRLTLSNKSTIEDFKKIFENQINPYDKGWLFNLKIKLFNFNNSNNNININNNNTNNNINS
What are the official names of this protein?
Putative ZDHHC-type palmitoyltransferase 3, Zinc finger DHHC domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VATA_ENTFA
Sequence: MQIGKIVKVSGPLILAENMSDASIQDICHVGDLGVIGEIIEMRGDVASIQVYEETTGIGPGEPVISTGEPLSVELAPGLIAEMFDGIQRPLDTFQEVTHSNFLGRGVKIDALDREKKWTFEPTVAVGEEVSAGDIVGVVQETPIIQHKIMVPFGVSGTIAEIKAGDFAIDETVYSVETAKGTESFSMMQKWPVRRGRPILEKLSPKVPMVTGQRVIDTFFPITKGGAAAVPGPFGAGKTVVQHQIAKWADVDLVVYVGCGERGNEMTDVLNEFPELIDPTTGESLMNRTILIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERAGQVIALGKDHREGSITAISAVSPSGGDISEPVTQNTLRVVKVFWGLDSQLAQKRHFPSINWLQSYSLYSTEVGQYLDLELQGNWAAMVAEGMRILQEESQLEEIVRLVGIDSLSDKDRLTLETAKSLREDYLQQNAFDDVDTFTSRTKQAKMLQLILTFGEEGQKALSLGTYFSELMAGTVEIRDRIARSKYLPEEELEKLDRLQAEIKTTIKEIIAEGGMTND
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: FDHD_ECO45
Sequence: MKKTQQKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_CHRSD
Sequence: MSKVLVLYYSSYGHVETLANAVAEGVRGVAGTQVDLYRVAELVPDEVAAKSGYKEDTTAAVLDDPSVLAEYDAIVVGTPTRFGNMASQMRNFWDKTGGLWAQGKLIGKLGGAFTSTASQHGGQETTLTSIHTTLLHHGMAVVGVPYSCPALTELDEVSGGTPYGATTIAGGDGSRQPSENELTIARFQGQHIAEMAAKLAG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: HCP_ACICJ
Sequence: MFCFQCEQTMRSETGAAGCGGPKGVCGKDEATADLQDVLIHQLKGIGQYVTRLQALGRRDAEADSFILYALFTTLTNVNFNRARFVEMIATAARLRDRLRDAYAEAASEAGQTPEALGGAAAFIPADSLVGLLAQANVASVRAGAEAVGEDVIGMRALLLYGLKGVAAYAHHAEVLGETREAIADGVARVLDLLAGDPVDLELMLEEALALGRVNFTVMEALDAANTGTYGAPTPTPVRITPVEGKAILVSGHDLRDLHAILEATKDTGINVYTHGEMLPAHGYPKLHAYSHLAGNYGTAWQNQQTEFAAFPGPIVMTSNCLIEPQPLYRNRIFTAGPVGWPGLRHIADGDFSPVVQAAKALPGFTRTEPERTVTTGFGREAVLGAAEQVIGAVKAGAIRHFFLIGGCDGAAPGRNYYTEFAEQAPDDTVVLTLGCGKYRFNTHEFGTIGGLPRMLDIGQCNDAYSALVIAQALAGAFECGVNDLPLSLVVSWFEQKAAAVFLTLLALGVRNVRLGPTLPGFLTPALLDILVNRFGVRPITSAEADIADALAPKAAA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORR1_ORYSI
Sequence: MEGGRGVTRVLLVDDSPVDRRVVQLLLSSSACAGSFHVIAVDSAKKAMEFLGLKEEGKEQAIDMVLTDYCMPEMTGYELLKAIKALSPLKPIPVIVMSSENEPQRISRCMNAGAEDFIVKPLQSKDVQRLRKCSPANTQCCDAGSDGKPPLLLLPSDHVVVDATAASPPPPPSRRRAHFAGVAMVLHSSSVELSHYFPFLFKFILLVYAILCLGELLHRWSNGCFLNLWCA
What is the function of this protein?
Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
What are the official names of this protein?
Two-component response regulator ORR1, Type A response regulator 1, OsRR1.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-A subfamily.
Protein: FMP41_YEAST
Sequence: MSYNYLKAARKIICIGRNYAAHIKELNNSTPKQPFFFLKPTSSIVTPLSSSLVKTTRPANSTFNGLNEDGTNPGPIFIPRGVKVHHEIELALIVSKHLSNVTKMKPEEVYDSISGVALALDLTARNVQDEAKKKGLPWTISKGFDTFMPISAIVSREKFSSYKSNLQDIFRVKCSVNGQLRQDGGTNLMLHPLHKILQHISTMISLEPGDIILTGTPAGVGELKPGDRVHCELLQNNDNIVDMNFECENRPGPYEFRET
What are the official names of this protein?
Uncharacterized mitochondrial hydrolase FMP41.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS15_XANOM
Sequence: MSVDTQKVIEDNKRSAQDTGSPEVQVALLTARIELLTGHFKTHKKDHHSRRGLLQMVNRRRSLLDYLKKKDNERYKSLIEKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TCMO_SOYBN
Sequence: MDLLLLEKTLIGLFLAAVVAIAVSTLRGRKFKLPPGPLPVPIFGNWLQVGDDLNHRNLTDLAKKFGDIFLLRMGQRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRHGWESEAAAVVEDVKKNPDAAVSGTVIRRRLQLMMYNNMYRIMFDRRFESEEDPIFQRLRALNGERSRLAQSFEYNYGDFIPILRPFLKGYLKICKEVKETRLKLFKDYFVDERKKLGSTKSTNNNNELKCAIDHILDAQRKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLRDEIDRVLGAGHQVTEPDIQKLPYLQAVVKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPAHWKKPEEFRPERFFEEESLVEANGNDFRYLPFGVGRRSCPGIILALPILGITLGRLVQNFELLPPPGQSQIDTSEKGGQFSLHILKHSTIVAKPRSF
What is the function of this protein?
Catalyzes the first oxidative step of the phenylpropanoid pathway in higher plants by transforming trans-cinnamate into p-coumarate (By similarity).  The compounds formed by this pathway are essential components for lignification, pollination, and defense against ultraviolet light, predators and pathogens (By similarity).
What are the official names of this protein?
Trans-cinnamate 4-monooxygenase, Cinnamic acid 4-hydroxylase, C4H, CA4H, Cytochrome P450 73, Cytochrome P450C4H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS2_STAAM
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKKVDEAYNFLKQVSEDGGQVLFVGTKKQAQESVKSEAERAGQFYINQRWLGGLLTNYKTISKRIKRISEIEKMEEDGLFEVLPKKEVVELKKEYDRLIKFLGGIRDMKSMPQALFVVDPRKERNAIAEARKLNIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTAKMADAILEGQQGVSNEEVAAEQNIDLDEKEKSEETEATEE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: 8ODP_RAT
Sequence: MSTSRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELLEESGLRVDTLHKVGHISFEFVGSPELMDVHIFSTDHVHGTPTESEEMRPQWFQLDQIPFADMWPDDSYWFPLLLQKKKFCGHFKFHGQDTILSYSLREVDEF
What is the function of this protein?
Oxidized purine nucleoside triphosphate hydrolase which is a prominent sanitizer of the oxidized nucleotide pool (PubMed:7586133).  Catalyzes the hydrolysis of 2-oxo-dATP (2-hydroxy-dATP) into 2-oxo-dAMP (PubMed:7586133).  Has also a significant hydrolase activity toward 2-oxo-ATP, 8-oxo-dGTP and 8-oxo-dATP (By similarity).  Through the hydrolysis of oxidized purine nucleoside triphosphates, prevents their incorporation into DNA and the subsequent transversions A:T to C:G and G:C to T:A (PubMed:7586133).  Also catalyzes the hydrolysis of methylated purine nucleoside triphosphate preventing their integration into DNA (PubMed:30304478, PubMed:32144205).  Through this antimutagenic activity protects cells from oxidative stress (PubMed:7586133, PubMed:30304478, PubMed:32144205).
What are the official names of this protein?
Oxidized purine nucleoside triphosphate hydrolase, 2-hydroxy-dATP diphosphatase, 7,8-dihydro-8-oxoguanine triphosphatase, 8-oxo-dGTPase, Methylated purine nucleoside triphosphate hydrolase, Nucleoside diphosphate-linked moiety X motif 1, Nudix motif 1.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus membrane. Cytoplasmic vesicle, secretory vesicle, acrosome.