PharMolix/UniProtQA huggingface dataset:
Protein: GDE1_BOVIN
Sequence: MWLWEEQGGLMGPFSFLLLVLLLLTRSPFNACLFTGSLYLLLRLFSFEPVPSRRAMQVLKPRDRVSAIAHRGGSHDAPENTLAAIRQAAKNGAAGVELDLEFTADGIPVLMHDSTVDRTTDGTGRLCDLTFEQIRKLNPAANHRLRNDFPNEKIPTLREAVAECLNHNLTIFFDVKGHAYKATDALKKVYMEFPKLYNNSIVCSFLPEVIYKMRQTDQNVVTALIHRPWSLSHTGDGKPRFESFWKQSMFVALDILLDWSMHNILWYLCGVSAFLAQKDFISPDYVKKWSAKGIQVVAWTVNTFDEKSYYESHLGSSYITDSMLEDCTPEF
What is the function of this protein?
Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol (By similarity).  Hydrolyzes glycerophospho-N-acylethanolamines to N-acylethanolamines in the brain and participates in bioactive N-acylethanolamine biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N-oleoylethanolamine (an anorexic).  In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl-lysoPlsEt) to N-acylethanolamine.  However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity (By similarity).  Has little or no activity towards glycerophosphocholine (By similarity).
What are the official names of this protein?
Glycerophosphodiester phosphodiesterase 1, Glycerophosphoinositol glycerophosphodiesterase GDE1, Lysophospholipase D GDE1, Membrane-interacting protein of RGS16.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Perinuclear vesicles and cell membrane.
Protein: LEA1_ORYSI
Sequence: MASRQDRREARAEADARRAAEEIARARDERVMQAEVDARSAADEIARARADRGAATMGADTAHHAAAGGGILESVQEGAKSFVSAVGRTFGGARDTAAEKTSQTADATRDKLGEYKDYTADKARETNDSVARKTNETADATRDKLGEYKDYTADKTQETKDAVAQKASDASEATKNKLGEYKDALARKTRDAKDTTAQKATEFKDGVKATAQETRDATKDTTQTAADKARETAATHDDATDKGQGQGLLGALGNVTGAIKEKLTVSPAATQEHLGGGEERAVKERAAEKAASVYFEEKDRLTRERAAERVDKCVEKCVEGCPDATCAHRHGKM
What are the official names of this protein?
Late embryogenesis abundant protein 1.
What is the protein family that this protein belongs to?
Belongs to the LEA type 4 family.
Protein: RL3L_BOVIN
Sequence: MSHRKFSAPRHGHLGFLPHKRSHRHRGKVKTWPRDDPSQPVHLTAFLGYKAGMTHTLREVHRPGLKISKREEVEAVTIVETPPLVVVGVVGYVATPRGLRSFKTIFAEHLSDECRRRFYKDWHKSKKKAFTKACKRWRDADGKKQLQKDFAAMKKYCKVIRVIVHTQMKLLPFRQKKAHIMEVQLNGGTVAEKVAWAQARLEKQVPVHSVFSQNEIIDVIAVTKGRGIKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPARVGCSIARAGQKGYHHRTELNKKIYRIGRGLHMEDGKVVKNNASTSYDVTDKSITPLGGFPHYGEVNNDFVMLKGCIAGTKKRVITLRKSLLVHHSRQALENIELKFIDTTSKFGHGRFQTAQEKRAFMGPQKKHLEKEKPETSGDL
What is the function of this protein?
Heart- and skeletal muscle-specific component of the ribosome, which regulates muscle function.  Component of the large ribosomal subunit in striated muscle cells: replaces the RPL3 paralog in the ribosome in these cells.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Inhibits myotube growth and muscle function.
What are the official names of this protein?
60S ribosomal protein L3-like.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RS11_PSEA8
Sequence: MAKPAARPRKKVKKTVVDGIAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGQAALEYGLKNLDVNVKGPGPGRESAVRALNACGYKIASITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FBK51_ARATH
Sequence: MSSMLSPPVKKRKIVAPQSQSASASFQSLPDDLILSIVARVPRLYHRTVSLVCKSFRSLLVSPELYKARSVSGHTESCLYLSIACYPDYRMFTLCRKPDQTLTTSEEEEKKKSNGYYLAPVPDPDSHPVYFSSLVTVGSDIYNIAGSHASSNVSILDCRSNTWREAPRLGVELTSVSASVLDRKIFVVGMYADDEESESKNDFFEVLDTETHTWDPQPFNCSETKDKFLNCRTAFIDGKFLVKPWIHRGVVAYNSKESRWEPVQTKMAMSMFNDSYCQIHNVIYLAFDGRIRWYDDALNCWGDVQGLLELGNIPHGPSCVRLADYRGNIAVFWFRYLPDNDDYKWKMIWCAEIALERRTSWEIWGKVLWFDPVLTVPADYEFVKALAATV
What are the official names of this protein?
F-box/kelch-repeat protein At3g06570.
Protein: ISPE_THEVB
Sequence: MYRLLAPAKINLFLQIIGNCLDGSGYHELVMVMQAVSLMDRLELIPRRDREIKVHCTNPAVPCDQRNLAYKAAALLQQHFPDRDGVEIFIEKRIPLGAGLAGGSTNAAAVLVGLDLLWQLGLTQGELQTLAAQLGADVPFCLQGGTALALGRGEQLTPLADLQGLTVILGKYRSLSVATPWAYQTYRQEFAATYAQTPSEQEKARQEGGSAILLQAIQQHDIAPLAANLRNDLEKVVLPRYPLVAELKEQFLAAGAIASMMSGSGPTVFALAPSADEGYRIMQRVRRALPDPDLDLWVCECCPHGIQLETS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: HLYC_RICPR
Sequence: MLKSSKHEDSSSKKNQNNKLIFIVRQLFYLIKHFFSKTKTPDNFFGIIKRLKINSQKMSLDEFNILANLLKLEDKIVEDIMVPRSDIIAIKLTTNLEELSESIKIAVPHTRTLIYDGTLDNVVGFIHIKDLFKALATKQNSPLKRLIRKHIIAAPSMKLLDLLAKMRRERTHIAIVVDEYGGTDGLVTIEDLIEEIVGRIDDEHDQQLDSANFKVINNSTIIANARIEVELLEEIIGEKLKNDDDEFDTIGGLVLTRVSSVPAIGTRIDISENIEIEVTDATPRSLKQVKIRLKNGLNSDNLT
What are the official names of this protein?
Hemolysin C.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family. Hemolysin C subfamily.
Protein: TRPD_CHLPM
Sequence: MAHTEILDTLQQGSKLSKPEMKRCMDAIMDGAIPDTAIATILTLLQKNGISADEIAGARESLIERATPITLDERAVDTCGTGGDSAGTFNISTAAALIANAAGVSIAKHGNRSVTSQCGSADVLEALGLPIELHPEATTALYRQTGFAFLYAPLYHPAMKKVAPVRKSLGIRTIFNILGPLLNPARVKRQLVGVFEPSLMELYAEALRQSGCSHALIVHGETESGLPLDEASVSGRTHIIELQNNVTCRHTTKPTDFHLQQWPIADLAGGTREENALLITRLLEGKATQAQREAALFAAAIACYVSGNANCIDEGICMAKEALAERRALRNLEAIIEISRDLERKYGTGKN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: HINT1_HUMAN
Sequence: MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG
What is the function of this protein?
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed:15703176, PubMed:16835243, PubMed:17337452, PubMed:17217311, PubMed:23614568, PubMed:28691797, PubMed:29787766, PubMed:31990367, PubMed:22329685).  Hydrolyzes adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate) (PubMed:15703176, PubMed:16835243).  Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester (PubMed:15703176, PubMed:22329685, PubMed:17337452).  Hydrolyzes 3-indolepropionic acyl-adenylate, tryptamine adenosine phosphoramidate monoester and other fluorogenic purine nucleoside tryptamine phosphoramidates in vitro (PubMed:17337452, PubMed:23614568, PubMed:29787766, PubMed:17217311, PubMed:28691797, PubMed:31990367).  Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide (PubMed:30772266).  In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1 (PubMed:16014379, PubMed:22647378).  Modulates p53/TP53 levels and p53/TP53-mediated apoptosis (PubMed:16835243).  Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex (PubMed:19112177).  Also exhibits SUMO-specific isopeptidase activity, deconjugating SUMO1 from RGS17 (PubMed:31088288).  Deconjugates SUMO1 from RANGAP1 (By similarity).
What are the official names of this protein?
Adenosine 5'-monophosphoramidase HINT1, Desumoylating isopeptidase HINT1, Histidine triad nucleotide-binding protein 1, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1, PKCI-1.
What is the protein family that this protein belongs to?
Belongs to the HINT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Interaction with CDK7 leads to a more nuclear localization.
Protein: RL11_PHEZH
Sequence: MAKKILGYIKLQVPAGAATPSPPIGPALGQRGVNIMGFCKEFNARTEKEQKGTPLPTVITVYQDKSFTFVTKTPPATYYIKQAVGLQSGSGKTGRETVGKITRAQLREIAEKKMKDLNANDVEAAARIIEGSARSMGLQIVEA
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CLE8_ARATH
Sequence: MKVLKRDSMLLLITLYFLLTTSMARQDPFLVGVEKDVVPAGTDLKQNKAKPHLPNLFRTMRRVPTGPNPLHHISPPQPGSLNYARN
What is the function of this protein?
Extracellular signal peptide that regulates cell fate (PubMed:16407446).  Represses root apical meristem maintenance (PubMed:16902140).  Positively regulates the expression of the transcription factor WOX8 and thus, regulates early embryo development (PubMed:22427333).  Regulates the transition of protophloem cells from proliferation to differentiation, thus impinging on postembryonic growth capacity of the root meristem; this signaling pathway requires CRN and CLV2 (PubMed:28607033).
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 8.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[CLE8p]: Secreted, extracellular space.
Protein: OPGD_ECOBW
Sequence: MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQRFDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLDAQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAGFRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFWFDTVKPGATTFTVYALLDSASITGAYKFTIHCEKSQVIMDVENHLYARKDIKQLGIAPMTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNPKGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVCFWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFSEGWAPGEHYPEKWARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSDSTDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: 4OMT1_PAPSO
Sequence: MGSSIDAETHEVDIKDQAQLWNIIYGYADSLVLRCTVEIGIADIIKNNNGSITLSELVSKLPLSNVNSDNLYRLLRYLVHLNILGQQTCAAGVDRVYSLKPVGTLLLKDSERSMAPVILGLSQKDFLFVWNFVKEGLGTGSTTAFEKAMGMDMWKYLEVNPNQSQLFDEGQAGETRLLTKTLLVDCRDTFQGMDSLVDVGGGNGTTIKAIHEAFPHIKCTLYDLPHVIANSDDHPNILKVPGDMFMSVPSAQVLLLKCVLHDWTDEHCVNILKKCKEAIPKETGKVIIVDVALEEESEHELTKARLILDIDMLVNTGGRERTAEDWENLLKRAGFRSHKIRPIRAIQSVIEAFP
What is the function of this protein?
Involved in the biosynthesis of benzylisoquinoline alkaloids.  Catalyzes the transfer of the methyl group to the 4'-hydroxyl group of 3'-hydroxy-N-methylcoclaurine to form reticuline.  Also involved in the papaverine biosynthesis.
What are the official names of this protein?
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase 1, 4'-OMT1, Ps4'OMT1, S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: NUOK_HELPJ
Sequence: MIGLNHYLIVSGLLFCIGLAGMLKRKNILLLFFSTEIMLNAINIGFVAISRYTHNLDGQMFALFIIAIAASEVAIGLGLVILWFKKYKSLDIDSLNAMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAU22_YEAST
Sequence: MTNEGIGINRDTSTICLREYVFIHFFPVKLISALTNKTNTMVKLTSIAAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVSDIRAHLAQYYLFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPAEQVTRVITGVPWYSTRLRPAISSALSKDGIYTAIPK
What are the official names of this protein?
Seripauperin-22.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
Protein: GLUC_CORGL
Sequence: MSTLWADLGPSLLPAFWVTIKLTIYSAIGAMIFGTILTTMRVSPVKILRTLSTAYINTVRNTPLTLVVLFCSFGLYQNLGLTLAGRESSTFLVDNNFRLAVLGFILYTSTFVAESLRSGINTVHFGQAEAARSLGLGFGATFRSIIFPQAVRAAIVPLGNTLIALTKNTTIASVIGVGEASLLMKATIENHANMLFVVFAIFAVGFMILTLPMGLGLGKLSERLAVKK
What is the function of this protein?
Part of the ABC transporter complex GluABCD involved in glutamate uptake.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutamate transport system permease protein GluC, Glutamate uptake system protein GluC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HFLD_HAES1
Sequence: MANYQDITFALAGVCQAAKLVQQLAMNGTVDQEILRTGLSTLLQTAPEDTLAVYGGQKSNLKLGLETLMEQLNGSDVTLNRYWLGLLALEGKLHKNAQAKSELARRIQYLPTQLAHYDLLDEQMLSTLASIYVDVISPLGARIQVQGSPLYLQQLMTQNRIRACLLTGIRSAVLWRQVGGTKWQFLFSRRKLVATAQQIYSSI
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: QUEA_STRPB
Sequence: MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFDHIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRLKVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLEDAERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDNLDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGGKFQGDIQADSGWTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFSFGDAMFVN
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDX1_GORGO
Sequence: MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPPHPFPGALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
What is the function of this protein?
Activates insulin and somatostatin gene transcription.  Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut.  Binds the DNA sequence 5'-CC[CT]TAATGGG-3' (By similarity).
What are the official names of this protein?
Pancreas/duodenum homeobox protein 1, Homeodomain protein PDX1, Insulin promoter factor 1, IPF-1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. IPF1/XlHbox-8 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: NUSB_PEDPA
Sequence: MSLNRHQIRESAFKIIFAKSANPDADLSELQDQVLEEFHETEAPDQFLKDLVMGVSLNLEAINETISGELKKGWTVKRLESPDRVILQMGTYEIKYTETPDKVAINEALELAKKYTDEDARKFINGVLSNIAK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: HEMA_INBF3
Sequence: DRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPKCLNCTDLDVALGRPKCMGTIPSAKASILHEVKPVTSGCFPIMHDRTKXRQLPNLLRGYENIRLSTHNVINAETAPGGPYKIGTSGSCPNITNGNGFFATMAWAVPKNDNNKTATNPLTVEVPYICTEGEDQITVWGFHSDNETQMVKLYGDSKPQKFTSSANGVTAHYVSQIGGFPNQAEDGGLPQSGRIVVDYMVQKSGKTGTITYQRGILLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKER
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RL9_DESAP
Sequence: MKVVLLKDVAGLGIRGQVVKVAEGYGRNYLIPKGLAEEATPGRIKELARLDQAREERVERLAAQARKVAAGLKGLTVRIPARAGEGGKLFGSVGNKDIAAALAARHNLKIDRKKLELKEPIRSLGKFPVLARLHPGVQVEFEVEVVDNGT
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NDHI_DESFU
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RSMJ_ECO8A
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_CAMJD
Sequence: MVDFRKFYKENANVAYTVLGYPNLQISEAFLQRLDQSPIDILELGVAYSDPIADGEIIADAAKIALDQGVDIHSVFELLARIKTKKALVFMVYYNLIFSYGLEKFVKKAKSLGICALIVPELSFEESDDLVKECEKYNIALITLVSVTTPKERVKKLVKHAKGFIYLLASIGITGTKSVEEAILQDKVKEIRSFTNLPIFVGFGIQNNQDVKRMRKVADGVIVGTSIVKYFKQENLDIIMKDIEEIFKK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ELMO2_MOUSE
Sequence: MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYVTEQTRNDIKNGTILQLAVSPSRAARQLMERTQSSSMETRLDAMKELAKLSADVTFATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSVTFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDKHLNPLDLPVTDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNVPGSGTEKRKAMYTKDYKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG
What is the function of this protein?
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility.  Acts in association with DOCK1 and CRK.  Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases.  May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).
What are the official names of this protein?
Engulfment and cell motility protein 2, Protein ced-12 homolog A.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Membrane.
Protein: YFCA_ECOLI
Sequence: METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALMAAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQYVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFGPAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKLLYDSHGQEILHWLGMN
What are the official names of this protein?
Probable membrane transporter protein YfcA.
What is the protein family that this protein belongs to?
Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRF_ASPNG
Sequence: MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAVIKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHIINCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKYKNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGADFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.