PharMolix/UniProtQA huggingface dataset:
Protein: PTAH_PESFW
Sequence: MSTNDEVFAKDNEFWKTYLRGRAQPPESFFERIFRYHEDHGGHFGTVHDCGAGNGPYSQKLRSRFKHVIVSDVAPGNVELAKERLGNDGFSFRVARVEDFDDIPTGSVDLVFATNVMHWVEPSRGAKAIVSQLKSGGTFIAAGFGPARFEDQKVQDIWTRISQSGGRRLIMKADDPTKILKVAVRSSRYYDVAPTDTSLFVPGTQRIHLNMNNGGLTDIVYPEDYVAAAEPSYTGPQDDEIFESEDGWSFETDLEGVKDHFATFPFSKEDPEVFAELWAELEKYVADGRPIRGCWPAKIILATRV
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes (PubMed:24302702).  The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA (PubMed:24302702).  As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain (PubMed:24302702).  The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and the intermediate to release atrochrysone carboxylic acid, which is spontaneously dehydrated to form endocrocin anthrone (PubMed:24302702).  Endocrocin anthrone is then converted to endocrocin, catalyzed by the anthrone oxygenase ptaC (PubMed:24302702).  Spontaneous decarboxylation of endocrocin occurs to generate emodin (PubMed:24302702).  An O-methyltransferase (ptaH or ptaI) could methylate emodin to form physcion (PubMed:24302702).  PtaJ could then catalyze the oxidative cleavage of physcion, and rotation of the intermediate could then afford desmethylisosulochrin (PubMed:24302702).  PtaF, a putative NADH-dependent oxidoreductase, might also participate in the oxidative cleavage step (PubMed:24302702).  Desmethylisosulochrin is then transformed by another O-methyltransferase (ptaH or ptaI) to form isosulochrin (PubMed:24302702).  Chlorination of isosulochrin by ptaM in the cyclohexadienone B ring then produces chloroisosulochrin (PubMed:24302702).  PtaE is responsible for the oxidative coupling reactions of both benzophenones isosulochrin and chloroisosulouchrin to RES-1214-1 and pestheic acid respectively, regardless of chlorination.
What are the official names of this protein?
Methyltransferase ptaH, Pestheic acid biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: NFRKB_XENTR
Sequence: MESLDSMLTDPLELGPCVESNGTGIMEECMLGGTRVSLPEDLLEDPDLFFEVVSRDTWKNVLSDSQREHLKQFLPVFPDDNANQQEKIIQSLFRGDNFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCLKSQYKRYLTSQQQYFHKLLKQILASRKELLDLARKNGPDQVLKKKPSSLRNTPEERETRAQCRYLKILREVKDECGDGTLSSEEEDLSSWLPESPTHCPSVAVPLRVIPTLSTQDMKTADKQEFTNHDLKLLLRRHREKRKRQSDHPDLITDNLSMNDIMTRVNAGRKGSLAALFDLATMKKRVKEKDDKKKKKLKTIKTEVEDYPDMPDEADIMPAVLPPETPQVTLTAVKEEPLEDVKPPLPFNEISACFFCLLLDILTMEGPCSLPLLEDKVSDWQSLPASTLNSWFSVAPNWCDLVHPALIYLSGECKVASSSFTPFVEFREKTQQWKCVVSSSDSEKELVAHFHLWLETKDQIYSKENEDCIDASTPIPRVRTDYIVRPSSGEEKHVFQEQERHRYIQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSAQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKAKKALQQKPKPPTKMKSGSKECSLKLCGTPEPAQLSLTESSMPPTPGTPGTPTPPALPSTPMSPSTSATVNKIVASTITETQKSSQSVLLVSSPAMPQLSTLLSPAVTSQSTSVTPTSGRAATISSSTGVPQVRIVTATTGVPTTQSAAVVTQPLSPVISHIRLPVTTTPTKALAQTQVVTVPVKNQTTIGASRLGASVTTQGSVTVNTLNSSAGLASKSVVSSPGASGPAILQSITGQSIIKQVALSGQLGVKSQPSSSLPLSSTNFRIQGKDVLRLPPSSITTDAKGQTILRITPDMMATLAKSQVTAVKLSQELFSAAPVSTTGKGLLHVTSSPSSPSPPAPSTIKLTPEMKPAETSSSSFRLMPALGISVAEQKGKVVTAGESKPATTIRIVQGLGVMPPKVSATQSITVSAKPVTVPSSTIVNPVHSASNVSLPTVNSTAVKTAPTGIVVGTGAATVRQIPVTTTQQGKLPARITVPLSVLSQPMKGKGVVTAPIIKGNLGANISGLGRNIILTTVPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLPQGTSPASSKAVSTVVVTTTPTTKPTQEPQ
What is the function of this protein?
Binds to DNA.
What are the official names of this protein?
Nuclear factor related to kappa-B-binding protein, DNA-binding protein R kappa-B.
What is the protein family that this protein belongs to?
Belongs to the NFRKB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPS_PECCP
Sequence: MSTAKLVKSAPSALLYTRNDLDDSVKTSTIALLNQLVVDFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTSIIDHQDTIAERVVQIGGVALGTVQIVGKQTSLKSYPTNIHSVQDHLKALAERYAIVANNVRKAIGKTEDEASADILTAASRDLDQFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPEB4_DANRE
Sequence: MQDDILESEMSKAPQLQQESQEGQDKQTLSPPGHQEPPGIISELDNALPEENQLEKGTMENANGKETLRLESPVLSGFDYQETTGIGTLAQSSSSSSSSLTGFSSWSTAMPPNPSTLIEEVGFFNQAATTNNAPPPLLFQSFSHHTSTGFGGNFSHQIGPLSQHHPSPHPHFQHPHNQHRRSSASPHPPPFSHRSAAFNQLPHLGNNLSKPPSPWGSYQSPSSTPSSTSWSPGGGYGGWGSSQGREYRRGGVNPLNSISPLKKSFPNNQTQTQKYPRNNSGFNTKPWVEDTINRNESIFPFQERSRSFDGFSMHSLENSLIDIMRAEQDSLKGHSSLFPMEDERSYGEDERSDQSLSGLGSPHSFPHQNGERIERYSRKVFVGGLPPDIDEDEITASFRRFGHLFVDWPHKAESKSYFPPKGYAFLLFQDESSVQALIDACMEEDGKLYLCVSSPTIKDKPVQIRPWNLNDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEIDKRVEVKPYVLDDQLCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWAAIHSRAGREFHKPLVKEGGDRPRHISFRWN
What is the function of this protein?
Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR.  RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism.
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 4, CPE-BP4, CPE-binding protein 4, CPEB-4.
What is the protein family that this protein belongs to?
Belongs to the RRM CPEB family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cell projection, dendritic spine. Postsynaptic density. Cell projection, axon. Cell projection, growth cone. Endoplasmic reticulum. Cytoplasm, perinuclear region.
Protein: PDE7A_RAT
Sequence: DQTALYIRMLGDVRVRSRAGFETERRGSHPYIDFRIFHAQSEIEASVSARNIRRLLSFQRYLRSSRFFRGATVCRSLNILDEDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLRRFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVNQPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLRESGLFSHLPLESRHEMEAQIGALILATDISRQNEYLSLFRSHLDKGDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQGDIEKKYHLGVSPLCDRQTESIANIQIGFMTYLQEPLFTEWARFSDTRLSQTMLGHVGLNKASWKGLQRQQPSSEDASAAFELNSQLLTQENRLS
What is the function of this protein?
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.  May have a role in muscle signal transduction.
What are the official names of this protein?
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, Rolipram-insensitive phosphodiesterase type 7.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE7 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: DLHH_YERPE
Sequence: MATAHHTDQLHSLQTHGIHCGETTIPSQGDELPAYIAKPDQHTGPYPVVIVVQEIFGVHEHIQDICRRLAKQGYLAIAPELYFRQGDAKDYSNINELVNNLVKKVPDRQVLVDLDHTAHWASRHGGDTKKLAITGFCWGGRIAWLYAAHNPQLKAAVAWYGKLVGEKTLFLPKYPVDVAIDLCAPVLGLYGGKDTSIPAEHIETMRQALRAANADAEIIVYPEAGHAFNADYRPSYHAESAQDGWQRMLDWFTQHGVSAIPIPEETQ
What are the official names of this protein?
Putative carboxymethylenebutenolidase, Dienelactone hydrolase, DLH.
What is the protein family that this protein belongs to?
Belongs to the dienelactone hydrolase family.
Protein: Y1496_MYCTO
Sequence: MAMMAASHDDDTVDGLATAVRGGDRAALPRAITLVESTRPDHREQAQQLLLRLLPDSGNAHRVGITGVPGVGKSTAIEALGMHLIERGHRVAVLAVDPSSTRTGGSILGDKTRMARLAVHPNAYIRPSPTSGTLGGVTRATRETVVLLEAAGFDVILIETVGVGQSEVAVANMVDTFVLLTLARTGDQLQGIKKGVLELADIVVVNKADGEHHKEARLAARELSAAIRLIYPREALWRPPVLTMSAVEGRGLAELWDTVERHRQVLTGAGEFDARRRDQQVDWTWQLVRDAVLDRVWSNPTVRKVRSELERRVRAGELTPALAAQQILEIANLTDR
What is the function of this protein?
Probable GTPase.  May also bind and hydrolyze ATP.  May function as chaperone (By similarity).
What are the official names of this protein?
Probable GTPase MT1543.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.
Protein: RP07_VAR67
Sequence: MVFQVVCSTCGKDISHERYKLIIRKKSLKDVLVSVKNKCCRLKLSTQIEPQRNLTVQPLLDIN
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG134, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 7 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 7 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: VG15_BPMD2
Sequence: MITAGLAGYVQRFASLFIRPALSIAEWLRLLQVLFPEVQRRYAEAADLGRDFYDSQRRLHHPELPRNERLRSDLQWEWFVRNMEPARKGLSQADSPQAAVTKLTLATVREVEMAGRRQIIGAVKNDPAPKIVKGWARVATGRETCAWCLMLISRGPEYLSADSGGLHLDTETVVDLWNEAGRDLEKFREETKPHIEEWHAGCDCLVVPVFDVENWPGKAAQERALQLWIDAGKEASQLIASGKARSKNENKETINALRRRLYRGEFAMSDYALAA
What are the official names of this protein?
Gene 15 protein, Gp15.
Protein: RF1_RICTY
Sequence: MSFSDNLVKILDKYENLGRKLSSGIIGDEFVKASKEYAELEDIVVKIKEYNKVKSELEEANNLRLEVALDNATLEMINNEIYILENLLPKLERAVRISLLPKDEADSKSAIIEVRAGSGGEEAALFAAVLFNMYQRYAEFKGWRFEILAISNTGIGGYKEASASIKGKDVFSKLKFESGVHRVQRVPETESQGRIHTSAATVAVLPEAEGVDIKIEDKDLRIDTYRSSGAGGQHVNTTDSAVRITHIPTGITVALQDEKSQHKNKAKALKILRARLYEEKRRQKEQERSDSRRWQVGSGDRSERIRTYNFLHGRVSDHRINLTLYKIDEVVKHGQLDEFIEALIANDEAKKLSEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_BACFR
Sequence: MNISYNWLKEYVNFDLTPDEVAAALTSIGLETGGVEEVQTIKGGLEGLVIGEVLTCVEHPNSDHLHITTVNLGNGEPTQIVCGAPNVAAGQKVVVATLGTKLYDGDECFTIKKSKIRGVESIGMICAEDEIGIGTSHDGIIVLPEDAVPGTLAKDYYNVKSDYVLEVDITPNRADACSHYGVARDLYAYLVQNGKQAALTRPSVDAFAVENHDLDIKVTVENSEACPRYAGVTVKGVTVKESPEWLQNKLRIIGLRPINNVVDITNYIVHAFGQPLHCFDANKIKGGEVIVKTMPEGTTFVTLDGVERKLNERDLMICNKEDAMCIAGVFGGLDSGSTEATTDVFLESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNITIYCLKLAAMMVKELAGGTISSEIKDVCAAPAQDFIVELTYEKVHSLIGKVIPAETIKSIVTSLEMKIMDETAEGLTLAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPSTLKSSLTTKGDCDKSNKLQNLVAEQLVGCGFNEILNNSLTRAAYYDGLESYPSKNLVMLLNPLSADLNCMRQTLLFGGLESIAHNANRKNADLKFFEFGNCYHFDAEKKNPEKVLAPYSEDYHLGLWVTGKMVSNSWAHADENTSVYELKAYVENIFKRLGLDLHSLVVGNLSDDIYSTALTVNTKGGKRLATFGVVTKKMLKAFDVDNEVYYADLNWKELMKAIRSVKVSYKEISKFPAVKRDLALLLDKKVQFAEIEKIAYETEKKLLKEVSLFDVYEGKNLEAGKKSYAVSFLLQDESQTLNDKMIDKIMSKLVKNLEDKLGAKLR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPP9A_BOTNU
Sequence: QWPRPQIPP
What is the function of this protein?
This peptide inhibits the activity of the angiotensin-converting enzyme (ACE) by a preferential interaction with its C-domain.  May also potentiate the hypotensive effects of bradykinin.
What are the official names of this protein?
Bradykinin-potentiating peptide 9a, BPP-9, BPP-9a, BPP-a.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: ADAD2_HUMAN
Sequence: MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN
What is the function of this protein?
Required for male fertility and normal male germ cell differentiation.
What are the official names of this protein?
Adenosine deaminase domain-containing protein 2, Testis nuclear RNA-binding protein-like.
What is the protein family that this protein belongs to?
Belongs to the ADAD family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Diffusely cytoplasmic early in pachytene spermatocytes and coalesces into several perinuclear granules by late pachynema.
Protein: PDXH_BURMS
Sequence: MTTLADLRTNYSRASLDAADVNPNPFVQFDVWFKEALDAQLPEPNTMTLATVDESGRPSARIVLIKGADERGFVFFTNYESRKGRELAHNPNAALLFYWIELERQVRVEGRIEKTSEEESDRYFASRPLGSRIGAWASEQSAVIESRALLEAREKEIGARFGENPPRPPHWGGYRLVPSSIEFWQGRPSRLHDRLLYTRDAASASGWKITRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: C3H16_ARATH
Sequence: MRKELCRNFQRGSCRYGENCRFLHPQQAKPNNPFGFGTQNQQQQQQQQQQNSSNPFGFGVQSGGSSRPNQFQNTWSRTASTPTGGGAAASTQQTGKQTQPADHKCTDPAACKRVMQDDFKNERPMWKLTCYGHWKYFPCDVTGDISYEELRAVAYEEAKRGIPLQSIVERERNLQNSKIAEFENFLRNPYKGSVTANQSPFAATTPSIFPQSSQINSPSPAFSGFNQQTAFSNTNAGGLSSSGPPNAFASFNQQTTFPNTNAGGVSSSGPPNPFASFTQQSNNQQTAFSNTNAGGLSSSGPPNAFASFNKQPNAFSVNTPQPVPSGPSGFQTNPSTTFKPASFGPGPGFATTPQNNNIFGQSTPTPATNTSQNNQTAFNFNVPVASFTAPAINTTNTSSGTELQIGGDPVDSSIWLKEKWNPGEIPEQAPPDAFV
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 16, AtC3H16.
What are the subcellular locations of this protein?
Nucleus envelope. Nucleus, nuclear pore complex.
Protein: MRAZ_DECAR
Sequence: MFEGAAALNLDAKGRLAIPARHRDALLAASEGSLVLTAHPHRCLLLYPSPAWQPIRDQILKASSLDPRAASIKRVLVGNARTEEPDSAGRILIAPELREYAKFEKTVYLVGMGTHFEIWSEAGWKQQNDLAAEALSGDLPPGFGDLVL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AMT11_ARATH
Sequence: MSCSATDLAVLLGPNATAAANYICGQLGDVNNKFIDTAFAIDNTYLLFSAYLVFSMQLGFAMLCAGSVRAKNTMNIMLTNVLDAAAGGLFYYLFGYAFAFGSPSNGFIGKHYFGLKDIPTASADYSNFLYQWAFAIAAAGITSGSIAERTQFVAYLIYSSFLTGFVYPVVSHWFWSVDGWASPFRTDGDLLFSTGAIDFAGSGVVHMVGGIAGLWGALIEGPRLGRFDNGGRAIALRGHSASLVVLGTFLLWFGWYGFNPGSFNKILVTYETGTYNGQWSAVGRTAVTTTLAGCTAALTTLFGKRLLSGHWNVTDVCNGLLGGFAAITGGCSVVEPWAAIICGFVAALVLLGCNKLAEKLKYDDPLEAAQLHGGCGAWGLIFTALFAQEKYLNQIYGNKPGRPHGLFMGGGGKLLGAQLIQIIVITGWVSATMGTLFFILKKMKLLRISSEDEMAGMDMTRHGGFAYMYFDDDESHKAIQLRRVEPRSPSPSGANTTPTPV
What is the function of this protein?
High affinity ammonium transporter probably involved in ammonium uptake from the soil, long-distance transport to the shoots and re-uptake of apoplastic ammonium that derives from photorespiration in shoots.  Contributes with AMT1-3 to the overall ammonium uptake capacity in roots under nitrogen-deficiency conditions.
What are the official names of this protein?
Ammonium transporter 1 member 1, AtAMT1;1.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHLB_NOSP7
Sequence: MKLAYWMYAGPAHIGTLRIASSFKNVHAIMHAPIGDDYFNVMRSMLSRERDFTPVTTSVVDRNVLARGSQEKVVDNIVRKDAEEHPDLIVLTPTCTSSILQEDLHNFVERAQLEAKGDVMLADVNHYRYNELQAADRTLDQIVQYYIEKARKRGELAEGKTAKPSVNIIGTTTLGFHNNHDCTELKRLMADLGIKVNTLIPEGASVNDLKKMSQAWFNLVPYRELGLTTARYLEEQFGTPYIDITPMGVVETARCIRKIQQVINAQGAEVDYENFINEQTLHVSQAAWFSRSIDCQNLTGKKAVVFGDNTHAAAITKILAREMGIHVVWAGTYCKYDAGWFREQVSEYCDEVLISEDHGEIGDAIARVEPSAIFGTQMERHVGKRLDIPCGVIAAPIHVQNFPIGYKPFMGYEGTNQITDLIYNSFTLGMEDHLLEIFGGHDTKEVITRGISADSDLNWTKDGQAELNKIPGFVRGKVKRNTEKFARDRGFKEINAEVLYAAKEAVGA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: SURE_ECO27
Sequence: MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDDGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_BURM7
Sequence: MNPEHSPLGKATVYANQYDASLLFPIPRAGAREQIGIGAPLPFFGTDIWNAYELSWLNARGKPQIAIATFYVPAESPNIVESKSFKLYLGSFAQTAFESADAVRDALKRDVSAACGASVTVRLATPAEFRKLQMDELDGLSLDRLDLDAHVYETDPSFLTASHDEAPVEETLVTDLLKSNCPVTGQPDWGSVQIHYVGAPIDHAGLLRYIISFRNHTGFHEQCVERIFVDILRACQPVKLAVYARYTRRGGLDINPFRTNYNQPMPDNARTARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTC3_CAEEL
Sequence: MSFPDEETDLLSEAKHCIRNVIHRTHRKFLENRLIGNFDSEDFSDAWKKKFAHAPTWCDADMSLQQIKRGKAVGNTVALTARAFFQLWLFRIGCFVQRWAWSTIFISLFLYCLCLGGLRHVTIETDLVKLWVSEGGRLNEEMGYLGQVKFERESGHLVHKVKRAVEQTTEPPAPAVKAEVRRGPELPKENGLGGGFQVVIQTPSFDGQNILSKEALQQHTKLMEEISTYEVKMFNETWTLSDICFKPPGPSFNSGPLAGIMSKLLDKIIPCIWITPIDCYWDGAKPLGPNPPLNLGPEVASFVSSLPPGNVTWKNLNPTSVIKEVGTLFDLGPIGNFFERAGIDGAYLDRPCIDPLEEECPKSAPNYFDRCHALTKFNEWNMAKAMSEQVTLERKIIPKDDGKSDIAETILNDIFGKKRRKRQADTTTKKPATKKDEDYYEYEDDADYLAGIANSTIAKKNPEKEAKDLLCLEYGSSLLKWMQENPERLGEFLTKEEMPDYPNYGDVMTGGCKGFGKKIMEWPEDLIIGGIQRDNGKLVSAEALQSVFLVSGAYDVFARIKNDKTDSHPGLDRHHFQPWMAGEIISTWQRNFTKRLYSHELNRERRQFHPLASTSIADMLEEFSQFNYIIIVIGYILMVIYAAFTQGRFQGWWLAVQSNVALAICGVILVTISSICGLGFATHLGINFNAATTQVVPFLSLGLGIDDMFLLLHNYDEIINICNKNEIGVLLKETGMSVMLTSINNILAFISGYVLPIPALRSFCSQTAILLAFNLIFLMFIFPAMIGIDLRRQRKGKRDLAYCSRGNPQMATSQSVPSNVSNMSSRAELAGYEKQADEYKRHEPWYTVGGFLNKIYIPALKNNVVKACVLIGTTTAVVFGLYGMYTSTLGLELADVLPEHTPPAAFLRAREQYFSFYPMFAVLRGDKLDIPNQQQLIEEYRAQLGSSKFMIKAEGKLQPYWMSMLRVWLQSLDMALEKDLAAGKFDLTNGNPIKVNGEKPSPESMIAARLVCSFGTNYNCDGRLGKMKMVENEVINPEGFYNYLTGWFNVDNMMYYVSQASFYPTPPGWEYNEKLAKVVPAAEPLLYSQMPFYQNDLIDTPAIVKMIEEIRATCEEYSERGLSNHPSGIAFTFWEQYLTLRWNLFQAICIIALAVFCVISILMFNPWAATLIMCIVVITTIELGGFMGLMGIKMNPISAVTLICAVGIGVEFTAHVELAFLTALGTIDQRLESCLQHMFVPVYHGAISTFLGVVMLVFSEFDFVVTYFFYTMTLLVALGVFNGLCVLPVILTLVGPKPELTPTDGSSVLPPPPPLRQQYAEKSGGVEGGMRKRKEKRPAEVEMSARDSPSTSSASHSSDDESSPAHK
What is the function of this protein?
Regulates osmosis during embryonic development.  Required for larval development and in particular is involved in larval molting.
What are the official names of this protein?
Protein patched homolog 3.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Note=Co-localizes with ajm-1, an adherens junction marker in hypodermal cells and vulval toroids.
Protein: AROE_XANAC
Sequence: MPVSRYAVFGHPVAHSLSPAIHADFGKQTGIALDYTAIDASLEDFSAALQRFADEGGKGANVTLPLKEAAYALASSLSDRARLAGAVNTLVRNDGQWQGDNTDGAGLVRDLTERQGLDLRGRRVLLLGAGGAARGVAPALLEAGITAMVVVNRSPERADALCDALGEPARVTSRYIEDLRELGDFELIVNATAAGRDRDAGAFALPLGLVNSLTAAVDLNYGDTAIAFLAWARAAQCRYAIDGLGMLVEQAAESFALWHGVRPDTDPVYAALRAREAVLISAD
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.