PharMolix/UniProtQA huggingface dataset:
Protein: CSK_ARATH
Sequence: MLLSAIASQTLLSSNPNLHFSNSIPNPRPSNPSLKLLNASSSSSSSSSSSIFTRGLRYVNHTVSNEESEPGGGETMVASASAIASAIRGASTTPVEFTQMIEKDHLKTKIILPSPDFQRLCLEQLDLFRQIVDPNAVLSIYVRPAGSYVMDRLELRRVTCYPSVNAGDVVILVGNFGIPAGLRAAEASLSSQQVELVSKHRAAVFPMVKHPFVVGFLVAELPVEAEEEEEEEEEEKPHGVNQFLSPEEAYALPASANTKSPRVKLPSVKVFTEEQRSYAINISRTLAMAYVMDQKTMLLQQSSWQNNVRMSKLVEQIRGPLSTMRTLSKMLSTHTKRNQISHDIVEDLIVQGDQIKDTLEELQDAVHLTKANIVRHNEEALKKINKTHNETRRSKYEHKDPIDGSQISSTRLSLGSGLDDSEMPMPPLALAPLQMHSIRPCDISNVLLDMVETVRPLALTQQRVVELGENSASLQVAVEEPALRQALSNLIEGALLRTHVGGKVEILSTRAPAGGSLVVIDDDGPDMRYMTQMHSLTPFGAELLSENMVEDNMTWNFVAGLTVAREILESYGCVIRVISPRSSDAALGAGGTRVELWLPAFPAAVSEANEA
What is the function of this protein?
Sensor kinase that senses the plastoquinone (PQ) redox state involved in stoichiometry adjustment of both photosystems (e. g.  long-term adaptation via transcriptional regulation of reaction center genes of photosystems I and II) and state transitions (e. g.  short-term adaptation involving reversible post-translational phosphorylation of light-harvesting complex II, LHC II), thus linking photosynthesis with gene expression in chloroplasts (PubMed:18632566, PubMed:22039472).  Autophosphorylates, probably on a tyrosine residue (PubMed:18632566).  Probably phosphorylates SIGA/SIG1 in response to plastoquinone redox state modification (PubMed:23754813).  Reduced PQ suppresses its autophosphorylation activity.  Represses expression of a number of chloroplast-encoded genes (PubMed:31925322).
What are the official names of this protein?
Chloroplast sensor kinase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the chloroplast sensor kinase protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Note=Associates with thylakoid membranes.
Protein: ABA4_MAGO7
Sequence: MGSIENPEIMASTMLHILPLAGKVYGITGGASGIGLATAQILSRRGATVCIADVDPKAMASAEVYFSGQSGAKYSITKVDISKRSEVNAWVDGIISQFGRLDGAANVAGVIGKIHGAVPVSEMDDDEWDKIVAVNLTGTMYCMRAQLRNIVDGGSIVNVASIHGLKGFANHAAYDASKHGVIGLTKAAAQENGAREIRVNAVAPGAIYTPLMQKNWDITGRPKDAPFDDPSAFRRQGTAMETGNVIAFLLGPDSTFVSGSVYSVDGAWI
What is the function of this protein?
Short-chain dehydrogenase/reductase involved in the biosynthesis of abscisic acid (ABA), a phytohormone that acts antagonistically toward salicylic acid (SA), jasmonic acid (JA) and ethylene (ETH) signaling, to impede plant defense responses (PubMed:26648962).  During pathogen-host interaction, ABA plays a dual role in disease severity by increasing plant susceptibility and accelerating pathogenesis in the fungus itself (PubMed:26648962).  The first step of the pathway catalyzes the reaction from farnesyl diphosphate to alpha-ionylideneethane performed by the alpha-ionylideneethane synthase ABA3 via a three-step reaction mechanism involving 2 neutral intermediates, beta-farnesene and allofarnesene (By similarity).  The cytochrome P450 monooxygenase ABA1 might then be involved in the conversion of alpha-ionylideneethane to alpha-ionylideneacetic acid (By similarity).  Alpha-ionylideneacetic acid is further converted to abscisic acid in 2 steps involving the cytochrome P450 monooxygenase ABA2 and the short-chain dehydrogenase/reductase ABA4, via the intermediates 1'-deoxy-ABA or 1',4'-trans-diol-ABA, depending on the order of action of these 2 enzymes (By similarity).  ABA2 is responsible for the hydroxylation of carbon atom C-1' and ABA4 might be involved in the oxidation of the C-4' carbon atom (By similarity).
What are the official names of this protein?
Short-chain dehydrogenase/reductase ABA4, Abscisic acid biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: ANMK_METC4
Sequence: MAMKRAIGLMSGTSLDGIDVALIESDGERIRLVKSANGLVAPLGPTGYRGYAEAERALLREATRDAEGLRARTDRPGRLAEAEDFVARAHAEAIEAFLAQNDLRPEDIDVVGFHGQTVIHRPKLGLTVQLGDGAALAKRLGIRVVSDMRANDVAQGGQGAPLVPVFHKALAEAAGFTGPLGILNIGGLANATLIDSGGNMLAFDTGPGNGPINDWMKERTGQDFDEGGATAARGTVDEDLLENLLGHPLILRAPPKSLDRNWFSHRLAGYLTVEDGAVTLTAFTAHAVARSLAFASERPARWIVGGGGAKNRTLMVMLERLLAAEVLNADAIGWSSDFLEAQAFAYLALRSLEGLPLTYPTTTGVAAPVTGGIVSEP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: DNLJ_EHRRG
Sequence: MTDQEEAKLILDKLNEKIRYHDLLYYTQDSPEISDAEYDDLCHQRSIILEKFPSLNSYYQDYIGGDPDSRFSKVKHNERMLSLDNAFNKQDVEKFMVRTRKLLDMKENESLCFSCELKIDGLSFSIIYKNGKLFQASTRGNGYFGENITNNVKTIENLPHTIQNAPDFLEVRGEVYIDRNDFIQLNNEGKNFANPRNAAAGSIRQLDPTITAQRKLKYCMYTIVNSNCLTQTESLNLLNSWGFCTNEHTISTDNFEEAINFYNKMYNNRSNISYDIDGIIYKINNIKLQHILGTTSKSPRWAIAYKFPAIEGKTKLNKISIQVGRTGVLTPIAELAPINIGGVVITRASLHNKSEIERKDIREGDYVIVKRAGDVIPQVVDVDKSLRTVELAEFNFPTACPACGSTVYQAQQEVSIYCMGGLFCHNQILEKIRHFVSKDAFNIIGLGKKQLLFFYEYGLITNIIDIFTLEEKINNKNIQLSSFNGWGEKSINNLLSAINNSKVINLENFIFSLGIRFVGKHIAKILANHFISYKNWYTEMLKLAQDVNYTINIQQVGLKTINSLRTFFTEQHNLNMINNLVEHLTIIDAQSNSYVSLIHGKTIVFTGELSSMSRSEAKLKSETAGAKVSSSLSKNTDFLIIGNNPGSKYKKAQSLNIQILSEDIWLQYIQPNKV
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL15_NEUCR
Sequence: MGALKYLEELQKKKQSDVVRFLLRVRCWELRQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRARVRRGGRKKPVPKGATYGKPTNQGVNQLKYQRSLKSTAEERVGRRCANLRVLNSYWINQDSTYKYFEVILVDPQHKAIRRDPRINWIVNPVHKHRESRGLTSTGKRSRGLNKGHRYNKTRAGRRKTWKRHNTLSLWRYR
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: QUED_ECO57
Sequence: MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
What are the official names of this protein?
6-carboxy-5,6,7,8-tetrahydropterin synthase, CPH4 synthase, Queuosine biosynthesis protein QueD.
What is the protein family that this protein belongs to?
Belongs to the PTPS family. QueD subfamily.
Protein: GLGA_STRP7
Sequence: MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYYDMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDFDDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVLTIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSYAHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAKNKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPAFEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGTLPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNLQKQAMESDFSWDTACKSYLDLYHSLVN
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: TF2B_MOUSE
Sequence: MASTSRLDALPRVTCPNHPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPSDFKFDTPVDKLPQL
What is the function of this protein?
General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II).  Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA.  Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex.  Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle.  Associates with chromatin to core promoter-specific regions.  Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner; these IIB-recognition elements (BREs) are localized immediately upstream (BREu), 5'-[GC][GC][GA]CGCC-3', and downstream (BREd), 5'-[GA]T[TGA][TG][GT][TG][TG]-3', of the TATA box element.  Modulates transcription start site selection.  Exhibits also autoacetyltransferase activity that contributes to the activated transcription.
What are the official names of this protein?
Transcription initiation factor IIB, General transcription factor TFIIB, RNA polymerase II alpha initiation factor.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Non-acetylated form colocalizes with DNA in the G0/1, S and G2 phases of the cell cycle, but not during mitosis. Acetylated form colocalizes at transcriptionally silent mitotic chromatids during mitosis at metaphase, anaphase, and telophase phases of the cell cycle.
Protein: UVRB_XANCB
Sequence: MTDRFELVSPYSPAGDQPAAIDKLVANFEAGLAKQTLLGVTGSGKTYTIANVVQQVQKPTLVMAPNKTLAAQLYGEFKSFFPNNAVEYFVSYYDYYQPEAYVPSSDTFIEKDSSINEHIEQMRLSATKTLLSRRDSLVVATVSAIYGLGAPEDYLSLRLILSIGEHIDQRQLIRHLTDLQYTRNEFELTRGAFRVRGEVLDVFPAESDTEALRIELFDGDIEQLTLFDPLTGETLRKLQRYTVYPKTHYATTRERTLSAVDTIKEELKERLEQLYSQNKLVEAQRLAQRTQFDLEMMAEVGFCNGIENYSRHLTGKAPGEPPPTLFDYLPPDALLVIDESHVTIPQIGAMYKGDRSRKETLVEFGFRLPSALDNRPLRFEEWEARSPRSIYVSATPGPYELRESAGEITELVVRPTGLIDPVVEIRPVGTQVDDLMSEVHERIKLGDRVLVTTLTKRMAENLTEYLGEHGIRVRYLHSDIDTVERVEIIRDLRLGKFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSTGSLIQTIGRAARNLRGKAILYADKMTRSMQAAIDETDRRREKQVEYNLEHGITPKSVARPISDIMEGAREDAAEKKAGKGRSKSRQVAEEPADYRAMGPAEIAGKLKALEQKMYQHAKDLEFEAAAQIRDQIQKLKAASLA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_DELAS
Sequence: MLSVKQELLAALAGELETLSPGAGARAAFESPKVAAHGDFACTAAMQLAKPLKLNPRSLGEQLKAALEATPSFQRWVDAIEIAGPGFLNIRLKPAAKQQIIREVLEQAEKFGWLADRGAKMLVEFVSANPTGPLHVGHGRQAALGDAICNLYATQGWGVHREFYYNDAGVQIDTLTKSTQLRAKGFKPGDECWPIDPENPASKAFYNGSYIQDIADDFLACKTVKADDREFTANGDVEDYDNIRQFAVAYLRNEQDKDLQAFNLHFDEYYLESSLYTNGYVEDAVQRLIAGGHTYELDGALWLKSTDYGDDKDRVMRKQDGNYTYFVPDVAYHIQKFKRGYSKVVNIQGTDHHGTIARVRAGLQAADVGIPAGYPDYVLHTMVRVVRGGEEVKISKRAGSYVTLRDLIEWTSKDAVRFFLLSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARICSVLAAWGGDAATLKDVDLSALEGPQAQALMLQLAKYPAMLTSAAEGNAPHDVTFYLRELASLYHSYYDAERILVDDEKVKLARLALISATRQVLHNGLAVLGVSAPQRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPTA_PAXIN
Sequence: MQVWAIIYDKADFPDTLYQNALPFVDQAVQSKIKRFHRREDACRSLIGSLLPRVLLRKRGVSRDEMTFATTENGKPYCTTPDIDPPLGFNVTHDESVIAMAFGSGDLGPPAYNLGVDVMQLKVPPRITFSEFVDSVSSQESDQLTARERNIVLADIPEGEALRRFYWVWTLKEAYTKALGIGLGFDFRRIQYDVLEEKVTIDGELARGWQFRKFEVAHSGNKYVGVAARFVGGRNPSITDLDEGSLVCYDAASFVNRAIEELV
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of an acyl-carrier-protein.  Activates the peptidyl carrier protein (PCP) domains of surfactin synthas.
What are the official names of this protein?
4'-phosphopantetheinyl transferase pptA, PPTase, Phosphopantetheinyl transferase.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily.
Protein: RS12_CYAPA
Sequence: MADEAIQEGEAAPSGTMDVMTALKEVLKKAMVVDGLKRGLHECAKALDQRSAQLCVLAANVNEPAYTRLVEALCAEHGINLIKVPENKQLGEWVGLCKIDKEGKARKVVGCSCAVITKFGEESEARQVLMEYLKKR
What are the official names of this protein?
40S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS12 family.
Protein: MHPB_AZOVD
Sequence: MTIKLKCLSHTPLRGLNDPGADVVAEVDAVLARSRAEVEAFDPELIVIFAPDHYNGLFYDLMPPFVIATAAESVADYGTLPGPLSIPRDLALDLTRHILDSGLDIALSHRLQVDHGCTQTLEELTGSLTRYPVIPIIINSVAPPFAPYRRIRKLGEAVGRFVASLGKRVLILGTGGLSHEPPVPLLSGAAEEIAEFLIAGRNPTPEARAARQARTIAAGKIYGTAESPLTPLNTDWDLAFIDLLVQGRLAEIDDFVVEEISTTAGRSTHEIRTWVAAFAALAAGGAYRARQDYYRPINEWIAGYGVVSAERR
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: YCIB_BURM9
Sequence: MKFLFDLFPIILFFAAFKLWGIFTATAVAIAATLAQVAWVAFRHRKVDTMLWVSLGVIVVFGGATLVLHDEKFIQWKPTVLYWLFAVGLVAARYAFGKNLIEKMMGKQLTLPEPVWDKLNLAWAAFFAALGVTNLYVVRNFTESQWVNFKLFGTTGAIVVFVILQSLWLAKYLKEE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LUXS_BACHK
Sequence: MPSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLLAFNLRKYIDRYPHFDIIDISPMGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPAANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: DDLB_ECO57
Sequence: MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRVEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSVRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase B, D-Ala-D-Ala ligase B, D-alanylalanine synthetase B.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIT1_YEAST
Sequence: MKLSSAFVLSAITVAALGESITTTITATKNGHVYTKTVTQDATFVWAGEGAAVTSAVTEASTVAATSAAAETSVAAETSIVEPSTSAQGTSADEGSGSSITTTITATKNGHVYTKTVTQDATFVWTGEGERAPASTVATVETSVAAETSVAEPSTSAQGTSADEGSGSSITTTITATKNGHVYTKTVTQDATFVWTGEGERAPVSTVATVETAASPVTSVAEPSASTDEGSGSSITTTITATKNGHVYTKTVTQDATFVWTGEGERAPASTVATSSISAIEIPSTTEASIVEASSAVETSSAAETSSAVETSSAVETSSAVETSSAAETSSAAETSSAVETSSAVEISSAVETSAVETSSSSSTIETTSVKSLSPTQTSLSSSVQASSPIETSSAAKTSSVVPTFSSTTTENSSNSKSTSAVVASTTTSSESSATIVTPTRIGQAYTESSSRDAQSVRTHESNNWSSSSSASTKMVSSITRVQTTTAGIFTNGKSSTTPQIVNYTGAADSIAAGTGLMGAALAAVIFL
What is the function of this protein?
Involved in the uptake of non-siderophore sources of iron and the siderophores ferrioxamine B and ferrichrome.  Has a role in the retention of iron in the cell wall and periplasmic space.
What are the official names of this protein?
Facilitator of iron transport 1.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI- anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI- CWP).
Protein: MINC_THESQ
Sequence: MVDFKMTKEGLILLIKDYQNLEEVLNAISARITQMGGFFAKGDRISLMIENHNKHSQDIPKIVSHLRNLGLEVSQILVGSTVEGKENDLRVQSRTTVESTGKVIKRNIRSGQTVVHSGDVIVFGNVNKGAEILAGGSVVVFGKAQGNIRAGLNEGEQAVVAALDLQTSLIQIAGFITHSKGEENVPSIAHVKGNRIVIEPFDKVSFERSE
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: LIPA_PYRCJ
Sequence: MELPSWIRVKAGDYGRIVAVREAVFAAGVHTICEEAHCPNIFSCWGEGTATFLILGDVCTRACKFCAVKTGDPRGFVDPTEPARVAEAVAKLGLRYVVITSVDRDDLPDGGASQFASVVKAVKARAPWAKVEVLTPDFGGSAEAVASVVEAGPDVYAHNLETVRRLTPLVRDRRASYDVSLRVLKMAKELGAVTKSGLMVGLGETFDEVLEALSDLRRVDVDIVTIGQYLKPRGHKRFLEVQRWVPPEEFEKYREAAEAMGFKAVVAGPLVRSSYKAHEAYLEMLRKTIGR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_PSYWF
Sequence: MKLSNKVTQLTDIIAPAVAACDVALWGVEFLPQGGRSLLRIYIEALPEDKAADKQVTIENCAAVTHQVSGVLEVHDPIAGEYVLEVSSPGLDRPFFAPEQMTDYMGQTINLRLIQAVGSGSSKRRKVTGKLEQLDDKQLSVVTADGERYDIALDNIDKANLIYQDL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCEH_ECO7I
Sequence: MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRESRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHQGD
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: RSMA_METM6
Sequence: MRQSKKLGQCFLKDKNFVKKAINRAEITDKDIVLEVGLGEGALTKELAKLAKKVYVIELDERLKPFADEITSEFENVEIIWSDALKVDLKNLGFNKIVANLPYQISSPITFKFLEEDFETAVLMYQYEFAKRMAGKPDTKEYSRLSVAVQYNADVEFICKVPPSAFSPKPDVNSAIVKLTKRKPKYSVKDEKFFKKVLKALFQHRNRTIKRALIDSSHEIEIERDALKEILEKIESEFDFTERVFKTPPEKIGHLSNLLYDEL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFH_BRADU
Sequence: MASLRQIAFYGKGGIGKSTTSQNTLAALAEMGQKILIVGCDPKADSTRLILHAKAQDTILSLAASAGSVEDLELEDVMKVGYQDIRCVESGGPEPGVGCAGRGVITSINFLEENGAYENIDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLICNERQTDKELELAEALAKKLGTQLIYFVPRDNVVQHAELRRMTVLEYAPDSKQADHYRKLAAKVHNNGGKGIIPTPISMDELEDMLMEHGIIKAVDESIIGKTAAELAAS
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: MURD_ROSS1
Sequence: MQLAGKRALVMGLGVHGGGTGVARFLALQGADVTVTDLRGPDDLRASLDALAGLPIRFVLGEHRDDDFRRAEIVVRNPAVPPNSRYLQIARAAGATIEMEMTIFFRLCPGPILGVTGTKGKTTTTLLLGAMLREQFPDTVIAGNLRISALEQLPTITATTPVVLELSSFALEGLGEAGLSPKIACITTIAPDHLDRHGTMEAYILAKEQIWRHQRPGDAVALNADSPIIRAMAVVEQRPDDVVWFASAAHPALAHAGRAAFWQGDELVWRDHRGGRHVICTRDDVQLRGTHNLGNIAAATAAACSFGVAPDHIRRAVQTFPGVEHRLELVRELDGVRYVNDTAATAPEAAIAALRTFDDPIVLIAGGADKQLPFDDLAREIAGRVKAVVLVDGTATPKLQRALRLVDPSVDVCGPFDDFERAVIAARHIAAPGDIVLLSPGCASFGMFRNEFHRGEAFRRIVESFT
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.