PharMolix/UniProtQA huggingface dataset:
Protein: AROC_SHEB9
Sequence: MSGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGKTTGTSIGLLIENTDQRSQDYSNIKDLFRPGHADYTYQQKYGMRDYRGGGRSSARETAMRVAAGAVAKKYLKQVHGIEIYGFMSQLGPICAQTIDLDQIEQNAFFFPDASKLEALDEYMRELKKSGDSIGAKISVIATGVPVGLGEPVFDRLDADIAHALMGINAVKGVEIGDGFGVVTQKGSEGRDLMSPQGFESNHAGGVLGGISSGQPIIAHIALKPTSSISVPGQSMTAQGEMAEVVTKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNQDVRSHTPVLGMR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RSMA_BARQU
Sequence: MPIDNLPPLREVIDIYGLQAHKSLGQNFLFDLNLTSKIAHQAGNIEGKPVIEVGPGPGGLTRALLAKGALVIAIERDERCIPALLAIEKHYPKKLKLICNDALKQNFSKLFETYPEKPRIIANLPYNIGTQLLLNWLLVEPWPPFYESMTLMFQREVAKRITAKPQSAYYGRLSVLTGWRTTAKIAFDVPPQAFIPAPKITSSVVHIIPRIQPLTCSAQKLSFVTKTAFGQRRKMLRQNLKTLGGEMLLAKAGIDGTRRAETLSISEFVTLANLVI
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_ECOHS
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase isozyme 1, ATP-PFK 1, Phosphofructokinase 1, 6-phosphofructokinase isozyme I, Phosphohexokinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIX_ECOLI
Sequence: MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDFSLREVQALADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDGLLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLDDVINQTVNRVLDQFAITLPEDLFARWQGA
What is the function of this protein?
Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD.  The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN (By similarity).  Acts in concert with UbiD to perform the decarboxylation of 4-hydroxy-3-octaprenyl-benzoate, a step in the biosynthesis of coenzyme Q (PubMed:16923914, PubMed:17889824).
What are the official names of this protein?
Flavin prenyltransferase UbiX.
What is the protein family that this protein belongs to?
Belongs to the UbiX/PAD1 family.
Protein: RL16_SYNAS
Sequence: MLMPKRVKYRKLQRGRRTGTATRGSKISFGEYGLQAEECGWITARQIEAARIAITRHVRRGGKIWIRIFPHKSITKKPAETRMGKGKGAPEEWVAVVKPGTVLYEMQGVSKEVAREAFRLASHKLPIGTRFLSRELTDEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SREK1_HUMAN
Sequence: MTSLMPGAGLLPIPTPNPLTTLGVSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEAV
What is the function of this protein?
Participates in the regulation of alternative splicing by modulating the activity of other splice facors.  Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6.  Augments the splicing activity of SFRS3 (By similarity).
What are the official names of this protein?
Splicing regulatory glutamine/lysine-rich protein 1, Serine/arginine-rich-splicing regulatory protein 86, SRrp86, Splicing factor, arginine/serine-rich 12, Splicing regulatory protein 508, SRrp508.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GET3_BLAGS
Sequence: MSSTAIVSGDESLEPTLQNLLDQKTLRWVFVGGKGGVGKTTTSCSLAIQLAKVRKSVLLISTDPAHNLSDAFGQKFGKEARLIDGFDNLSAMEIDPNGSIQDLLAAGGDQADDPMGGLGLGGMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIIFDTAPTGHTLRFLQFPTVLEKALGKLSQLSSQFGPMLNSVLGARGGLPGGQNLDEILSKMESLRETIGEVNAQFKDADLTTFVCVCIAEFLSLYETERMIQELTSYQIDTHCIVVNQLLFPGKDSSCEQCKARRKMQKKYLNEIEELYEDFNVVRMPMLVEEVRGKEKLEKFSNMLINPYIPPQE
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: FABH_HELPH
Sequence: MEFYASLKSIAMHVPSERVKNAEFQQFLDTSDEWIEKRTGIKERRFASNEEKSSDLGVIAAKQAIERAHLTPKDIDLVVVATLSPDFLAMPSTACVLSAKLGIENKPAFDISAACTGFIYLLSVAKAYVESGMCENVLIVGAEKTSSVLDFKDRGTCILFGDGAGACVIGRTKRLKESILDVQISANGNFSNYLYTPRTLKPTPFNSKEEALEPFLCMKGNEVFKLAVKTLLKDVETILEKNALKPEDVRLFIPHQANFRIIQAVREHLDFKDEQVVLTVHKYGNTSAASIPMAMCEAYEEGRLKKGDLMLLDAFGGGLTWGSALVYFGG
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PME59_ARATH
Sequence: MNMMMQKLSILFLHLILLVLLCVHPLTTVADRNSTDWCDKTPYPDPCKCYFKNHNGFQQPTQLSEFRVMLVEAAMDRAISARAELTNSGKNCTDSKKQAVLADCIDLYGDTIMQLNRTLHGVSPKAGAAKSCTDFDAQTWLSTALTNTETCRRGSSDLNVTDFITPIVSNTKISHLISNCLAVNGALLTAGNKGNTTANQKGFPTWLSRKDKRLLRAVRANLVVAKDGSGHFNTVQAAIDVAGRRKVTSGRFVIYVKRGIYQENINVRLNNDDIMLVGDGMRSTIITGGRSVQGGYTTYNSATAGIEGLHFIAKGITFRNTAGPAKGQAVALRSSSDLSIFYKCSIEGYQDTLMVHSQRQFYRECYIYGTVDFIFGNAAAVFQNCLILPRRPLKGQANVITAQGRADPFQNTGISIHNSRILPAPDLKPVVGTVKTYMGRPWMKFSRTVVLQTYLDNVVSPVGWSPWIEGSVFGLDTLFYAEYKNTGPASSTRWRVSWKGFHVLGRASDASAFTVGKFIAGTAWLPRTGIPFTSGL
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Probable pectinesterase/pectinesterase inhibitor 59.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: HOA4_BURL3
Sequence: MTDQTNKIYLSDVTLRDGMHAIRHQYSLDSAVAIARALDDAGVDSIEVAHGDGLSGSSFNYGFGAHTDLQWIEAVAGTVKRAQVATLLLPGIGTVHDLRAAYDAGARIVRIATHCTEADISKQHIAYARELGMDTVGFLMMSHMTSPDALAQQAKLMESYGAQCVYVVDSGGALGMRDVAARFDALKAVLDPATQTGMHAHHNLSLGVANSIVALEHGCDRIDASLTGMGAGAGNAPLEVFVAAVDRLGLHHGCDVKQLIDAAEDIVRPLQERPVRVDRETLALGYAGVYSSFLRHTEAAAAKYGLSAFDIMVELGRRRMVGGQEDMIVDVALDMLKAREAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 4, HOA 4, 4-hydroxy-2-keto-pentanoic acid aldolase 4, 4-hydroxy-2-oxopentanoate aldolase 4.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: GSA_PROMP
Sequence: MTDILKTTYSEEVFSSALELMPGGVSSPVRAFKSVGGQPIVFDRVKGPYAWDIDGNRYIDYIGSWGPAICGHAHPEVITALQEAIEKGTSFGAPCVLENKLAEMVIDAVPSVEMVRFVNSGTEACMAVLRLMRAFTGRDKVIKFDGCYHGHADMFLVKAGSGVATLGLPDSPGVPRTTTANTLTAPYNDLEAVKKLFSENPDAISGVILEPIVGNAGFITPEPGFLEGLRELTTENGSLLVFDEVMTGFRISYGGAQEKFGVTPDLTTLGKVIGGGLPVGAYGGKKEIMSMVAPSGPVYQAGTLSGNPLAMTAGIKTLELLKQEGTYEKLESTTSRLIEGIIQSAENNGIAINGGSVSAMFGFFLCEGPVRNFEEAKTNNSELFGKLHREMLKRGVYLAPSPFEAGFTSLAHSEEEIDRTLEAFDQSFSVIKN
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_CERS1
Sequence: MGYVRTGILMAVMTALFLGVGALIGGQSGAIIALVIAAGMNLFTFWNSDRAVLSMHGAHEVDPRAAPDLYNMVRGLADRAGMPMPKLYLIETDQPNAFATGRNPENAAVAVTRGLLRALTPEEVAGVVAHELAHIRNRDTLLMTVTATFAGAISMLANFAFFFGGSSNEEGERPMGLVGTLALMFLAPLAAGLVQMAISRSREYEADRIGAEICGRPLWLASALGKIEGLAQRIDNVRAERNPATAHMFIVNPLHAMGHDRLFATHPNTANRIAALRAMAEGAPQASRIPRVAARRGPWN
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACACA_MOUSE
Sequence: MDEPSPLAKTLELNQHSRFIIGSVSEDNSEDEISNLVKLDLEEKEGSLSPASVSSDTLSDLGISGLQDGLAFHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQDLYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFASNLNHYGMTHVASVSDVLLDNAFTPPCQRMGGMVSFRTFEDFVRIFDEIMGCFCDSPPQSPTFPESGHTSLYDEDKVPRDEPIHILNVAIKTDGDIEDDRLAAMFREFTQQNKATLVEHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTTTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMSLKSPEYPDGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGESSLAYDEVITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELSPTERKELESKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDSPST
What is the function of this protein?
Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20952656).  This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA (PubMed:20952656).
What are the official names of this protein?
Acetyl-CoA carboxylase 1, ACC1, ACC-alpha, Acetyl-CoA carboxylase 265.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: APT_PARPJ
Sequence: MSNALASAPLDAADYIKSHIRTVPDWPQPGVQFRDITPLLQEPKSLRVLIDLFVQRYIDAKLDYIAGLDARGFIIGPILAYELNLGFIPIRKAGKLPYKRVAQSYELEYGTATVEIHEDACKPGDRIVIIDDLIATGGTMMAGKILLERLGAVVVEGAAIIDLPELGGSKLLREGGLALYTVTGFDGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_HALH5
Sequence: MNVRDFDFHLPEKLIAQTPLKDRTASRLLVLDKHTGAVEDKKFPDLLQFIEAGDCLVLNDTRVLPARLFGVKEETGAQVEVLLLKQMEGDRWETLVKPAKRLKVGTIIRFGNGELTATCVQELEHGGRVLEFSYEGIFHEVLDQLGEMPLPPYIKEQLDDKDRYQTVFAKNRGSAAAPTAGLHFTEELLDQLKQKGVHLAFITLHVGLGTFRPVSVEEIEEHEMHAEFYQMSAGTARLLNEVKRQGGRIIAVGTTSARTLETIRQEHDEFVETSGWTSIFIYPGYEFKGIDGLITNFHLPKSTLVMLVSALAGRENLLNAYAHAVKQSYRFFSFGDAMFIYDKKTNS
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
Protein: PRP8_DICDI
Sequence: MDDTNSNINQSNESQHLEEKAKKWIQLNNKKYSEKRKFGAVEIRKEDMPPEHLRKIIKDHGDMSNRRFRDDKRVYLGALKYMPHAILKLLENIPMPWEQVKYVKVLYHLSGAITFVNEIPFVIEPIYIAQWATMWVTMRREKRDRTHFRRMKFPLFDDEEPPLDYSDNILDNEVEDPIQMELDENDDSEVIDWLYDSKPLVNTKFVNGSSYRKWRLNLPIMSTLFRLASPLLSDLTDSNYFYLFDDNSFFTSKALNMAIPGGPKFEPLFRDVDDDDEDWNEFNDINKVIIRNKIRTEYKIAFPYLYNSRPRKVKTPTYHTPNNCYIKNDSPDLPGFYFGAALNPIPSYKTSGNKNEQSEYGTEDDEFQLPEEIETILSKTEIEHDNLANGIQLYWAPRPFSLRSGTTRRAEDIPLVKSWYKEHCPSEHPVKVRVSYQKLLKCHVLNKLHHRKPKAQTKRNLFKSLKATKFFQSTEIDWVEAGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFYLKPIKTLTTKERKKSRFGNAFHLCREILRLTKLVVDVHVKFRLGDADAFQLADAIQYLFSHLGLLTGMYKYKYRLMRQIRMCKDLKHLIYYRFNTGAVGKGPGCGFWAPMWRVWLFFLRGIVPLLERWLGNLLARQFEGRQTKGMAKTVTKQRVESHFDYELRAAVMHDILDMMPEGIKANKSRIILQHLSEAWRCWKSNIPWKVPGLPIPIENMILRYVKSKADWWTNIAHYNRERIKRGATIDKTASKKNLGRLTRLWLKAEQERQHNYLKDGPYVSAEEAVAIYTTTVHWLEKRRFSAIPFPQTSYKHDIKILTLALERLKEAYSVKSRLNQSQREELSLVEQAYDNPHDALARIKRHLLTQRTFKEVGIEFMDMYTHLVPIYDVDPFEKITDAYLDQYLWYEADKRQLFPNWVKPSDNEPPPVLIHKWCQGINNLDQVWETSQGECVVLLETQFSKVYEKMDLTLMNRLLRLIVDQNIADYMSGKNNVVINYKDMNHTNSYGLIRGLQFASFIFQYYGLVLDLLVLGLERASALAGPPNLPNSFLTFPSVQTETAHPIRLYSRYVDRIHVLYKFTADEARKLIQKYMSEHPDPNNENVVGYNNKKCWPRDCRMRLMKHDVNLGRAVFWQIKNRLPRSLTTIDWEDSFVSVYSKDNPNLLMNMAGFDIRILPKCRTPLDQLAPKDAVWSLQNVNTKERTAQAFLRVDTESQERFENRIRMILMASGSTTFTKIVNKWNTALIGLMTYYREAVVTTREMLDILVRCENKIQTRVKIGLNSKMPNRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLKYSKQTDTGITHFTSGMSHDEDQLIPNLYRYIQPWEQEIKDSQRVWAEYAIKYEEAKSQNKNLTLEDLEDSWDRGIPRINTLFQKSRHTLAYDKGWRVRTDWKQYQVLKNNPFWWTNQRHDGKLWNLNNYRTDIIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKYKKLTHAQRSGLNQIPNRRFTLWWSPTINRKNVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESLVMDLCQVFDQELDNLEISVVNKEAIHPRKSYKMNSSCADILLRATHKWQVSRPSLLNDNRDTYDNTTTQYWLDVQLKWGDFDSHDIERYSRAKFLDYTTDSMSLYPSPTGCLIGLDLAYNIYSSFGNWFLGVKPLVQKAMAKILKSNPALYVLRERIRKGLQLYSSEPTEPYLSSQNFGELFSNKIMWFVDDSNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTDVWLGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIATRKGMMDPLEVHLLDFPNIVIQGSELQLPFQACLKVEKFGDLILKATEPKMVLFNIYDDWLSTIHSYTAFLRLILILRALHVNLERTKIILKPNKNVITQPHHIWPTLTEQEWLTVEGSLKDLILADFGKRNNVNVASLTQSEIRDIILGMEISAPSQQREDQIAEIEKQKTEASHLTAVTVRSTNIHGEEIITTATSPHEQKVFSSKTDWRVRAISATNLHLRTNQIYVNSDNAKETGGFTYVFPKNILKKFITIADLRTQIMGYCYGISPPDNPSVKEIRCIVMPPQWGTPVHVTVPNQLPEHEYLKDLEPLGWIHTQPTELPQLSPQDVITHSKIMSDNKSWDGEKTVIISVSVAWPCTLTAYHLTPSGFEWGKNNKDSLNYQGYQPQFYEKVQMLLSDRFLGFYMVPDRGSWNYNFMGVKHSTNMTYGLKLDYPKNFYDESHRPAHFQNWTQMAPSANDDEENQPENENLFE
What is the function of this protein?
Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs.  Required for the assembly of the U4/U6-U5 tri-snRNP complex.  Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur.  Interacts with both the 5' and the 3' splice site.
What are the official names of this protein?
Pre-mRNA-processing-splicing factor 8 homolog, Splicing factor Prp8.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: EIF3B_ASPFU
Sequence: MAPSFDTLSEQDLHEEEEEEIDFSDLKAQYEVKLEEGLDTFVVIDGLPVVPEESRQKLIKFLLRKLNTVGHTSEDAVFMPLNDKNMSEGYAFVEFETPEQAVAAVKQLHGTPLDKKHTLLVNKLMDIERYGREGRIDEEYKPPAIEPFKEKEHLRSWLADPNARDQFALYRGDKVGVFWNNKNHPPENVVDRAHWTQLFVQWSPKGTYLASVHPQGVQLWGGPAFSKQKQFPHPFVQLIEFSPGESYLTTWSARPIQVEEGQSILTYEEEGKNIIVWDIATGKPLRSFVSHDLTAGPAGDAEPKKKVQWPAFKWSADEKYVARMLQHQSISIYELPRMNLLGKTSVKIDGVMDFEWSPATVTREGVKQYEQLLCFWTPEIGSSPARVAMMSVPSKEIVRTRNLFNVSDVKLHWQSQGLYVCVKVDRHSKSKKSMATNLEIFRVREKGVPVEVVDSLKDTVINFAWEPNGNRFVLITTGEAVAGAAVAPKTAVSFFAPEKKGGAIGNFKLIRTIEKKNSNAIYWSPKGRFVVVATVHSQTSFDMDFWDMDFEGEKPEAEKDFAANLQLMKTTEHYGVTDIDWDPTGRYVVSSASVWTHQLENGWNLHTFAGQTLSENPTDKFKQFLWRPRPPTLLSKEEQKQVRKNLREYSKEFDEEDRYAVDIANTAVVEKRKRVLNEWIAWIRREKELLAEEKDAYGLPEEADDPKLAKDAAATTQEQGETVVEEIVEEIIEESEEVIG
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3 p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LNT_METCA
Sequence: MKAMLLALTGGILLPFAFAPFGYALVAPLSLALLFRVWLNASPSKAALYGYLFGLGQFGIGVSWVFVSMYEYGGSDVFSAAGLTALFVAYLALFPALAGWLGVKAGGGSILVRTLLVFPAAWVVTEWLRGWLFSGFPWLQIGYSQTDTGLRSIAPVFGVFGVGWLLAVLAGLLLSAWLLDRRGRRFALLGAAVVLVGSTQFAKVQWTHPAGDPIRVTLLQGNVPQDQKWRPEAKTTTVQMYVDMTRQHWDSRLIIWPETAVPAFYQQVAESFLAPLEAEARQHGVDVLVGVPYYEAQGNRYYNALVTLGAKPGRYFKRHLVPFGEFLPLRPVLAFVLDILQIPLADFTAGAHRQTLLQAAGYPLIASICYEDIFGQESLTGLPEGAYLVNVTNDAWFGDSFAPHQHWQKARMRALETGRYMLRATNTGVTGIIDAGGRPVAVAPMFEREALTGMMQPMAGATPYALWGDWPAIGLCAGIVGICFARRRRNASSHQGRQAEPGRN
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CA1A_CONST
Sequence: YCCHPACGKNFDC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin blocks muscular nAChR alpha-1/gamma subunits.
What are the official names of this protein?
Alpha-conotoxin SIA, S1A.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL10_THET8
Sequence: MPNKRNVELLATLKENLERAQGSFFLVNYQGLPAKETHALRQALKQNGARLFVAKNTLIRLALKELGLPELDGLQGPSAVVFYEDPVAAAKTLVQFAKSNPKGIPQVKSGLLQGQILTAKDVEALAELPTMDELRAELVGVLQAPMAELVGVLGGVARELVGILEAYAEKKAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MRF3_ARATH
Sequence: MEGFLTDQQREMMKVATQTADDLPPSQKPHSVLLEHLPKPSGGGKASGASNAVKHRRSHAGRSIRSKKDGGGGKGNWGKLIDTDGDYHIDPNDPNYDSGEEPFELVGATLSDPLDDYKKAAASIINEYFSTGDVDVAAADLIELGSSEYHPYFIKRLVSVAMDRHDKEKEMASVLLSALYADVINPNQIRDGFVLLLESADDFVVDIPDAVNVLALFLARAVVDDILPPAFLPRAAKALPITSKGYQVVQTAEKSYLSAAHHAELVERRWGGQTRTTVEEVKKKIADILNEYVETGETYEACRCVRELGVSFFHHEVVKRALVTALENHAAEAPVLKLLNEAASENLISSSQMVKGFSRLRESLDDLALDIPSARTKFGLIVPKAVSGGWLDASFGYPSGECGRQQNEDEKLKRFKEDIVTIIHEYFNSDDIPELIRSLEDLGAPEYNPIFLKKLITLALDRKNHEKEMASVLLSSLHIEMFTTEDVADGFVMLLESAEDTALDILDASNELALFLARAVIDDVLAPFNLEEISSKLRPNSSGTETVKMARSLIFARHAGERLLRCWGGGSGWAVEDAKDKISNLLEEYESSGLVSEACKCIHELGMPFFNHEVVKKALVMGMEKKKDKMMLDLLQESFSEGLITTNQMTKGFTRVKDGLEDLALDIPNAKEKFNDYVEYGKKNGWVSSSFLTSLTEDANVG
What is the function of this protein?
Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions (PubMed:29084871).  Involved in the regulation of the ethylene-mediated signaling pathway (PubMed:21631530).  Involved in salt stress responses (PubMed:21631530).  Reduced cotyledons size and early flowering (PubMed:21631530).
What are the official names of this protein?
MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 3, EIN2 C-terminus interacting protein 1, MA3 domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the PDCD4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.