PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_COCHE
Sequence: MFKYQTILSPLDQFEIRNLFSIDTPLLANMNLSITNIGLYMTIAAFIAFYFSILATNHSKITPNKWSLSQETLYATIHSIVVNQINNKNGQAYFPFMYTLFIFILINNLIGMVPYSFASTSHFILTFSLSFTVVLGATVLGFKEHGLKFFSLFVPAGCPLGLLPLLVLIEFISYLARNVSLGLRLAANILSGHMLLNILSGFTYNIMSSGIIFFILGLLPLAFIIAFSGLELGIAFIQSQVFVVLSCSYIKDALELH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GP5D_CHLMU
Sequence: MEYTLQTLVFCSFKGGTGKTTLSLNVGCNLAQFLGKRVLLIDLDPQSNLSSGLGASIEGNHKGLHEVMCASNDLKSIICKTKKTGVDIIPASFLSEQFREFSTNGIPSSNLRLFLDEYCSPLYDVCIVDTPPSLGGLTKEAFIAGDKLIVCLIPEPFSILGLQKIREFLISIGKPEEEHILGVALSFWDDRSSTNQTYIDIIESIYENKIFSTKIRRDISLSRSLLKEDSVINVYPTSRAATDILNLTHEISALLNSKHKQDFSQRTL
What are the official names of this protein?
Virulence plasmid ParA family protein pGP5-D.
What is the protein family that this protein belongs to?
Belongs to the ParA family.
Protein: EIF3H_MAGO7
Sequence: MADTFKESPIKSVQVEALVVMKIAKHCSSSFPTIATGSIVGMDNDTLVEVTNSLNFPTVDVANVDSHQSERDASAQAAAAPRSKANLMYQAEMIKHLREVNVDANCVGWYTSATMGNFVTMSFIENQAHYQRENPKAIALVHDVSRSSQASLSLRAFRLSTAFMTALKENKFTTENLQKTKLTYKDILIEMPVVIHNSHLLTTYLHQIPSAPAAGSETTIPTSLAALQREPVNIPPYPSIDSLELSIDPFLEKTCDLLLDSIEAHYTDLNNHQYYQRQMTREQAKITAWQAKRKAENAARAAAKQEPLPDDEWKRLFKLPQEPSRLEGMLNARQVEQYSKQVDGFTANVSAKMFAVRGSLLTE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_METMP
Sequence: MLIFVKSGENMLESILKNTSEIVSIEELTELLKKEEKIAYIGFEPSGRIHMGHYLQIRKMIDLQKAGFKIVILLADLHAYLNQKGTMDEVRALGEENRKVFEAMGLVADYVYGSEFQLKDEYTIDVYKLALSTTLNRARRSMEVIAREDENPKVASVVYPLMQVNDIKHLNADVAVGGMEQRKIHMLSREILPSMGYKAPVCIHNPVLTGLDGEGKMSSSKGNFIAVDDDEATIKKKMKNAFCPMKEVSGNPVLEIAKYYLKYPATVKRPEKFGGDLVLESYEALENAFVEGLHPMDVKNLVSEQLIEILRPIREKMNK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGT5A_CRIGR
Sequence: MAFFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYDLKKTLAVLLDNILQRIGKLESKVDNLVNGTGANSTNSTTAVPSLVSLEKISVADIINGVQEKCVLPPMDGYPHCEGKIKWMKDMWRSDPCYADYGVDGTSCSFFIYLSEVENWCPRLPWRAKNPYEEADHNSLAEIRTDFNILYSMMKKHEEFRWMRLRIRRMADAWIQAIKSLAEKQNLEKRKRKKILVHLGLLTKESGFKIAETAFSGGPLGELVQWSDLITSLYLLGHDIRISASLAELKEIMKKVVGNRSGCPTVGDRIVELIYIDIVGLAQFKKTLGPSWVHYQCMLRVLDSFGTEPEFNHASYAQSKGHKTPWGKWNLNPQQFYTMFPHTPDNSFLGFVVEQHLNSSDIHHINEIKRQNQSLVYGKVDSFWKNKKIYLDIIHTYMEVHATVYGSSTKNIPSYVKNHGILSGRDLQFLLRETKLFVGLGFPYEGPAPLEAIANGCAFLNPKFSPPKSSKNTDFFIGKPTLRELTSQHPYAEVFIGRPHVWTVDLNNREEVEDAVKAILNQKIEPYMPYEFTCEGMLQRINAFIEKQDFCHGQVMWPPLSALQVKLAEPGQSCKQVCQENQLICEPSFFQHLNKEKDLLKYRVTCQSSELYKDILVPSFYPKSKHCVLQGDLLLFSCAGAHPTHQRICPCRDFIKGQVALCKDCL
What is the function of this protein?
Promotes proliferation of umbilical vein endothelial cells and angiogenesis, at least in part by promoting the release of the growth factor FGF2 from the extracellular matrix.
What are the official names of this protein?
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase, GlcNAc-T V, GNT-V, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Secreted alpha-1,6-mannosylglycoprotein 6-beta- N-acetylglucosaminyltransferase A]: Secreted.
Protein: MFM3_PHOSM
Sequence: MAATNDPELTRRKQRQEDFLRGTSKINFDDHIDHCVLSGKTAIVTGGASGIGHGIAQALSSNGCKVAVLDLSGPLEAGTDESNIDSPKLFECDVSSWESLLAAFQEVLIWSGNSLDIVVLSAGVRSHNIKDLILERPAGSTSTPVKPPSSVFDVNLLGTYYSAYLALWYFTNLEAKRDEAEFNWKPQLLFIGSLASYVEQPLSADYCASKHGVRGLWKSVRSHSALFGDCQTNLLAPTFIDNRQGSTKSRGDGALISLTNDVKLGEVSDVVAGALRCLCDRNIEGRALCCVKGEQSSPGSNNFDLCDNLIDFNAGKSVLDSFRNGVVGRLGTQNTTGPQ
What is the function of this protein?
NADP-dependent dehydrogenase; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS) (PubMed:27056201).  SQS1 is composed of a 2,8-dioxobicyclic[3. 2. 1]octane-3,4,5-tricarboxyclic acid core that is connected to two lipophilic polyketide arms (PubMed:27056201).  These initial steps feature the priming of an unusual benzoic acid starter unit onto the highly reducing polyketide synthase pks2, followed by oxaloacetate extension and product release to generate a tricarboxylic acid containing product (By similarity).  The phenylalanine ammonia lyase (PAL) M7 and the acyl-CoA ligase M9 are involved in transforming phenylalanine into benzoyl-CoA (By similarity).  The citrate synthase-like protein R3 is involved in connecting the C-alpha-carbons of the hexaketide chain and oxaloacetate to afford the tricarboxylic acid unit (By similarity).  The potential hydrolytic enzymes, M8 and M10, are in close proximity to pks2 and may participate in product release (By similarity).  On the other side, the tetraketide arm is synthesized by a the squalestatin tetraketide synthase pks1 and enzymatically esterified to the core in the last biosynthetic step, by the acetyltransferase M4 (PubMed:11251290, PubMed:15489970, PubMed:28106181).  The biosynthesis of the tetraketide must involve 3 rounds of chain extension (PubMed:11251290, PubMed:15489970, PubMed:28106181).  After the first and second rounds methyl-transfer occurs, and in all rounds of extension the ketoreductase and dehydratase are active (PubMed:11251290, PubMed:15489970, PubMed:28106181).  The enoyl reductase and C-MeT of pks1 are not active in the final round of extension (PubMed:11251290, PubMed:15489970, PubMed:28106181).  The acetyltransferase M4 appears to have a broad substrate selectivity for its acyl CoA substrate, allowing the in vitro synthesis of novel squalestatins (Probable).  The biosynthesis of SQS1 requires several oxidative steps likely performed by oxidoreductases M1, R1 and R2 (Probable).  Finally, in support of the identification of the cluster as being responsible for SQS1 production, the cluster contains a gene encoding a putative squalene synthase (SS) R6, suggesting a likely mechanism for self-resistance (Probable).
What are the official names of this protein?
NADP-dependent dehydrogenase M3, Squalestatin S1 biosynthesis cluster protein M3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: HBS1_SCHPO
Sequence: MSRHRDVKNLDLDDYELDEEPGEEELTEEQEEEFRSAVATVRETLLGVPISEKEIADTVWYYYFDVEKSVNYLLQKASSKAGAKEKQNTDSQKEKKQNKSKEALADAKDPLDESSNGIKNLSLNKNDEPAFQTNGEVKMKNSSESDNQPEKKKIKKQNPTDLVSVPEIFEQSNPKPVVHLVVTGHVDSGKSTMLGRIMFELGEINSRSMQKLHNEAANSGKGSFSYAWLLDTTEEERARGVTMDVASTTFESDKKIYEIGDAPGHRDFISGMIAGASSADFAVLVVDSSQNNFERGFLENGQTREHAYLLRALGISEIVVSVNKLDLMSWSEDRFQEIKNIVSDFLIKMVGFKTSNVHFVPISAISGTNLIQKDSSDLYKWYKGPTLLSALDQLVPPEKPYRKPLRLSIDDVYRSPRSVTVTGRVEAGNVQVNQVLYDVSSQEDAYVKNVIRNSDPSSTWAVAGDTVTLQLADIEVNQLRPGDILSNYENPVRRVRSFVAEIQTFDIHGPILSGSTLVLHLGRTVTSVSLKIVTVNNKRSRHIASRKRALVRISFLDGLFPLCLAEECPALGRFILRRSGDTVAAGIVKELC
What is the function of this protein?
Involved in protein translation.  Together with dom34, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs (By similarity).
What are the official names of this protein?
Elongation factor 1 alpha-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFRNP_PYRAB
Sequence: MIRFVLDTSIFVNPDVRKKFGETPTKAMKTFLKYAESLFGHVEFYMPPGIYREVMHFVEEEEVSPDIELYIIKKPPNVHDIKIPAFVVYELIEDIRRRVDKGLRVAEKAVRESVIDTSNVDKIIQKLRRNYRKALREGILDSKEDFELILLAKELDGIIVSADVGILTWAEKMGIKWVDAFKFKEVLEELVEKLKRSESEKERK
What is the function of this protein?
RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.
What are the official names of this protein?
RNA-free ribonuclease P, RNA-free RNase P, Protein-only RNase P.
What is the protein family that this protein belongs to?
Belongs to the HARP family.
Protein: MRAY_BURMA
Sequence: MLLALAQWLQGDASFLRLFTYLTFRAVMATITALVIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLILIGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRVFDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIALTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAYVMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIFVAETLSVMLQVTWFKYTKKRYGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPG_THEP1
Sequence: MRKSVKVGNVVIGGGAPVSVQSMTTTKTADVERTISQIKRLERAGCEIIRVAVQDEEDAKAIRRIKEQIEIPLVADIQFDYRLAILSIDNGADKIRINPGNMSRDRLKDVVAAAKGKGIPIRVGANVGSIKRRTSERWKDLAESALEEVRLLEKEGFYDIVVSVKSSDILETIKANEYIAEKIEYPIHLGVTEAGVSETAVVKSSIAIGHLLLKNIGDTIRVSISGDPVREVIVGKKILIALGLREGVEVIACPTCGRAEIDVENMAKMIEENFFHVQKRLKIAVMGCVVNGIGEGKDADLGVAGLRDGAVIFVKGEIKERVSKEFVLERLKHYLNELLEEVER
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: TRMD_FLAJ1
Sequence: MRIDIITVLPELLRSPFEASIMKRAIDKGLVEVHFHNLRDYTTNKQKSVDDYQFGGGAGMVMMIQPIDDCITHLKSEREYDEIIYMSPDGETLNQKMANKMSMYENIIILCGHYKGVDQRVRDHFITKEISIGDYVLSGGELGALVLSDALIRLIPGVLSDETSALTDSFQDNLLSGPIYTRPADYKGWKVPEVLTSGHAAKIEKWREDAAYEHTKNRRPDLLEEH
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2743_CUPMC
Sequence: MATSEAPINLTNQFLIAMPGMADPTFSGSVVYLCEHNERGALGLVINRPIDIDMATLFDKIDLKLEIQPVAHQPVYFGGPVQTERGFVLHDPVGIYVSSLAVPGGLEMTTSKDVLEAVANGSGPHRFLLTLGYAGWGAGQLEDELSRNGWLTVQADPEIIFSVPPEERFAAAIRLLGIDISMLSGDAGHA
What are the official names of this protein?
UPF0301 protein Rmet_2743.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: SSB_VIBVU
Sequence: MASRGINKVILVGNLGNDPEIRYMPSGGAVANITVATSETWRDKATGEPREKTEWHRVTLYGKLAEVAGEYLRKGSQVYIEGQLQTRKWQDQNGQDRYSTEVVVQGYNGIMQMLGGRQQQGGAPAMGGAPQQQQGGWGQPQQPAAQPSYQKQAPAQQQPMQSQPQYNEPPMDFDDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: Y437_METJA
Sequence: MEIIHYIVIIMTLLSSLASLLQRDLIKCIILSGFAGLCMAYLYYALLAPDVALTEAILGGAILPALFAFTVRRTQRIDE
What are the official names of this protein?
Uncharacterized protein MJ0437.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZN443_HUMAN
Sequence: MASVALEDVAVNFTREEWALLGPCQKNLYKDVMQETIRNLDCVVMKWKDQNIEDQYRYPRKNLRCRMLERFVESKDGTQCGETSSQIQDSIVTKNTLPGVGPCESSMRGEKVMGHSSLNCYIRVGAGHKPHEYHECGEKPDTHKQRGKAFSYHNSFQTHERLHTGKKPYDCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGKAFFWPSLLHMHERTHTGEKPYECKQCSKAFSFYSSYLRHERTHTGEKPYECKQCSKAFPFYSSYLRHERTHTGEKPYKCKQCSKAFPDSSSCLIHERTHTGEKPYTCKQCGKAFSVSGSLQRHETTHSAEKPYACQQCGKAFHHLGSFQRHMIRHTGNGPHKCKICGKGFDCPSSLQSHERTHTGEKPYECKQCGKALSHRSSFRSHMIMHTGDGPHKCKVCGKAFVYPSVFQRHERTHTAEKPYKCKQCGKAYRISSSLRRHETTHTGEKPYKCKLGKACIDFCSFQNHKTTHTGEKPYECKECGKAFSRFRYLSRHKRTHTGEKPYECKTCRKAFGHYDNLKVHERIHSGEKPYECKECGKAFSWLTCFLRHERIHMREKSYECPQCGKAFTHSRFLQGHEKTHTGENPYECKECGKAFASLSSLHRHKKTHWKKTHTGENPYECKECGKAFASLSSLHRHKKTH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 443, Krueppel-type zinc finger protein ZK1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LKHA4_COCIM
Sequence: MKMATPANPLRDPNTLSNYNKFRTVHTSVNFEIRFDQKRLVGNVIHRLKSLTNAESKEVILDSSYLEVKSVKVNGEAAEWQLLPRFEPYGSPLKISLEQAIPLDELIEVDISVNTTEKCTALQWLNPEQTSNGKHPYMFSQCQAIHARAIFPCQDTPDVKATFDFNLSSPLPVIASGVPVKQDASPPQSSGSIYYRFEQKVPIPSYLFAIASGDIAQAQIGPRSHVAVSPDRLDECKWELEGDTERFLQTIGNIIFPYVWGEYNVLILPPSFPYGGMENPVYTFATPSIISKDRQNVDVIAHEISHSWSGNLVTNCSWEHFWLNEGWTTYLERRIQAAIHGEPYRHFSAIIGWKHLVDSVERHGDTHEFTKLVVDLKGKDPDDAFSSVPYEKGFTFIFHLENLIGKDKFDKFIPHYFTRFRGKSLDSYEFKSCILDFFASDEESHVLLNKLDWDSWFYKPGLPPKPSFDTSLVDVVYELANKWKYISQSSFSPKASDMDGLVANQIVVFLEQVLLFDNPLTPEQSRFMGQVYNFAQSQNIEVSYLYLQVGLKAGDDSIVEPTIKLLGEIGRMKFVRPLYRTLEKFNRDIAVDTFEKHKNFYHPICRGLLEKDLFGDKGA
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase 2, Epoxide hydrolase, Leukotriene A-4 hydrolase homolog, LTA-4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y2600_NATPD
Sequence: MQTVSTETVPGHETVEALGIARGNTVEARNVGRDITQSIRNITGGELKAYSELLSKARDEALSRMEADAEEMGADAVVNVRLETSKVTDGGSEVIAYGTAVRLR
What are the official names of this protein?
UPF0145 protein NP_2600A.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: GUF1_YEAS7
Sequence: MLKFRIRPVRHIRCYKRHAYFLRYNHTTTPAQKLQAQIEQIPLENYRNFSIVAHVDHGKSTLSDRLLEITHVIDPNARNKQVLDKLEVERERGITIKAQTCSMFYKDKRTGKNYLLHLIDTPGHVDFRGEVSRSYASCGGAILLVDASQGIQAQTVANFYLAFSLGLKLIPVINKIDLNFTDVKQVKDQIVNNFELPEEDIIGVSAKTGLNVEELLLPAIIDRIPPPTGRPDKPFRALLVDSWYDAYLGAVLLVNIVDGFVRKNDKVICAQTKEKYEVKDIGIMYPDRTSTGTLKTGQVGYLVLGMKDSKEAKIGDTIMHLSKVNETEVLPGFEEQKPMVFVGAFPADGIEFKAMDDDMSRLVLNDRSVTLERETSNALGQGWRLGFLGSLHASVFRERLEKEYGSKLIITQPTVPYLVEFTDGKKKLITNPDEFPDGATKRVNVAAFHEPFIEAVMTLPQEYLGSVIRLCDSNRGEQIDITYLNTNGQVMLKYYLPLSHLVDDFFGKLKSVSRGFASLDYEDAGYRISDVVKLQLLVNGNAIDALSRVLHKSEVERVGREWVKKFKEYVKSQLYEVVIQARANNKIIARETIKARRKDVLQKLHASDVSRRKKLLAKQKEGKKHMKTVGNIQINQEAYQAFLRR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: POTA_BORGP
Sequence: MDNCILEIRNLSHYYDNNGNKTLDNINLKIKKNEFITLLGPSGCGKTTLIKILGGFLSQKNGEIYFFSKEISKTSPNKREINTVFQNYALFPHMNVFDNISFGLRMKKTPKDIIKEKVKTSLSLIGMPKYAYRNINELSGGQKQRVAIARAMVMEPKLLLLDEPLSALDLKMRQEMQKELKKIQRQLGITFIYVTHDQEEALTMSDRIVVMNEGIILQVGTPEEIYNEPKTKFVADFIGESNIFDGTYKKELVVSLLGYEFECLDKGFEAEEAVDLVIRPEDIKLLPKGKGHLSGIITSAIFQGVHYEMTLEIQKTNWIVQSTRLTKVGEEVDIFLEPDDIHVMHKE
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TSDB_RHOJR
Sequence: MSAFAQPPGAGRKAVDVAIVGSGPTGMALAALLGCQGRSVVVLERYTGLYNLPRAAAFDDETMRTFQKLGVAEKMLPGTNVQRGYVWVNGDDEVLLDIEFDNPGRCGWPAQYMMYQPHLESVLDELITSLPTVEIRRGMTVESVDQQDGDDVLVRATDVEGSAYLVRARYVVGCDGGNGVVRQFAGGELDDYGFFENWLVCDFQLNRDVPDLPTFRQVCDPAEPIAIVNIGPRFHRFSFRLESAANREEVVHPDKVWPRVATYLTPEDAELVRVANYTFRSCITTQWRHRRILLAGDAAHQMPPFLAQGMVSGIRDARNLAWKLDMVLAGHPDSLLDTYQAEREPHVRYITEKAIELGRVQTMRDTALAAQRDAQMIAARKANQKPDKLRYPALSGGLIANHGDMFPQGLVSTSSTTALFDEIAGTGWLVVADGPQVLSGIAEGDRTAFTEIGGKEVIFGLTSMFDGAPVSDTAGVYTRWFAAHECVAAIVRPDGYVFGLARDAAELAGLAKELVAAVAPVPSRPPAPTA
What is the function of this protein?
Single-component hydroxylase that is part of the gamma-resorcylate (GRA) degradation pathway.  GRA is initially converted by GRA decarboxylase to resorcinol, which is hydroxylated by resorcinol 4-hydroxylase.
What are the official names of this protein?
Probable NADH-specific resorcinol 4-hydroxylase.
Protein: DMFAB_ALCSP
Sequence: MKDIAIRGYCDRPSVATGETIRFYVSANETRGTFDAELVRLIHGDSNPAGPGYKEEAIKSDLEGQYPARFQRTQFGSYVEVADPDAGLQPDGAFSVHLFLWSTTPSRGRQGIASRWNDERQSGWNLAIEDGRVVFTIGDGSGATSSVVSDRPLFQQIWYSITGVYDPEKKQLRLYQKSVVNRTNSRFGLVVPLDSDCAVSADATVKAADSETSLLIAGLGEAAAQDGRTWCIAHYNGKVDAPKIYGCALGQDDAEKLSRGEIVRPISRLAHWDFSAGIGLNGIPTDHVVDASGNGHHGRCMNQPDRGSTGWNWDGHEENFIHCPEQYGALWFHEDCLDDCRWEKDFEFTVPEGLKSDFYAVKIRYEDTEDYIPFFVLPPRGTATAPILVIASTLSYLAYANEQIMHKADIGQAVAGHTPVLNENDVELHKNLSYYGLSTYDGHIDGRGVQYTSWRRPIMNLRPKHRQGFGSIWELPADLHLIDWLNHNGFEYDVATEHDLNDQGAELLRRYKVVLTGSHPEYQTWANADAWEDYLADGGRGMYLAANGMYWIVEVHPEKPWVMEVRKELGVTAWEAPPGEYHYSTNGRRGGRFRGRARATQKIWGTGMSSFGFDHSGYFVQMPDSQDERVAWIMEGIDPEERIGDGGLVGGGAGGYELDRYDLALGTPPNTLLLASSVEHSVVYTVIPDDKAFPHPGMNGGEHPFVRADITYFSTANGGGMFATSSISWLGSLSWNDYDNNVSKMTKNVLNQFIKDEPAPRV
What is the function of this protein?
Hydrolyzes N,N-dimethylformamide, and to a lesser extent N,N-dimethylacetamide and N,N-diethylacetamide.  Has no activity against the substituted amides N-methylformamide, N-ethylformamide, N-ethylformamide and N-methylacetamide or the unsubstituted amides formamide, nicotinamide, acetoamide, benzamide, acetamide and acrylamide.
What are the official names of this protein?
N,N-dimethylformamidase beta subunit, N,N-dimethylformamidase heavy chain.
Protein: MOBA_YERPE
Sequence: MQPNITGVILAGGRSSRMGGNDKGLIPLNGKPLFQYVIDRFKPQVSDLVINANRNQGLYKESGIPVIDDIITGFVGPLAGMHAGLSYASTEWVVFAPCDVPALPSDLVSQLWQGKKQALAAYANDDERAHPTFALMHISLKTQLADYLIRGDRKLMLFLDSINAQRVKFSGKADLFSNLNTPADCDLWEQKRRGQ
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITD_MONPU
Sequence: MAEAAARILEALPAVCEYRWSCKDASKRFTVVNPATGEPITVVQAGNLDTVQGAIQASHRAFESWRWKTRQERSLYLLQAADELQKHSHELAVLLCLENGKPVKDASFDVGFLVQVFRYFGSIVDKLPSEFFDQGSIYSSVIYEPHGVCVGILPFNWPPVHAGGKLAPCLAAGNTMVLKPGEQAPLTLMRIVEILQSVFPADVVQAVPGLGPEIPQALINHPLVKMVSLTGSTASGSQAAQTAAVTLTPTVLELGGKNAFVVFEDADLELVVRDAIDGAFFNKGESCTAASRILVHKDLYPTLVSRLTAAVKKLRTGDGLDETTHIGPVVSRERQQEVLSYIEQGKREGATLAAQGDPPTAGRLSGGFFVPPTLFTDVTADMTIAQREIFGPVVTVGSFETEEEAVKTVNSSQYGLFAGVYSSDFTRAMRVTRKLDVGVVLVNNYFRALLGTPFGGVKDSGYGREHWIGTLREWSRVKNVRFPSGLSPIPAWGGAVDVCKL
What is the function of this protein?
Aldehyde dehydrogenase; part of the gene cluster that mediates the biosynthesis of the mycotoxin citrinin, a hepato-nephrotoxic compound to humans due to inhibition of respiration complex III (PubMed:17586673, PubMed:19012408, PubMed:19111642, PubMed:28238725, PubMed:27913218).  The pathway begins with the synthesis of a keto-aldehyde intermediate by the citrinin PKS (pksCT) from successive condensations of 4 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit (PubMed:28238725).  Release of the keto-aldehyde intermediate is consistent with the presence of the C-terminal reductive release domain (PubMed:28238725).  Mp11 collaborates with pksCT by catalyzing the hydrolysis of ACP-bound acyl intermediates to free the ACP from stalled intermediates (By similarity).  Mpl2 then catalyzes the oxidation of the C-12 methyl of the ketone intermediate to an alcohol intermediate which is further oxidized by the oxidoreductase mpl7 to produce a bisaldehyde intermediate (PubMed:27913218).  The fourth catalytic step is catalyzed by the mpl4 aldehyde dehydrogenase (PubMed:27913218).  The final transformation is the reduction of C-3 by mpl6 to provide the chemically stable citrinin nucleus (PubMed:27913218).
What are the official names of this protein?
Aldehyde dehydrogenase mpl4, Citrinin synthesis protein mpl4.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.