PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_MARSD
Sequence: MKTKFIFITGGVLSSLGKGLAAASIGALLKARGMTATIQKLDPYINVDPGTMNPFQHGEVYVTDDGAETDLDLGHYERYLDVSLSQKNNMTSGRVYHNVITKERRGDYLGGTVQVIPHITDEIKNAVMNVPNGEDVALIEIGGTVGDIEGLPFLEAIRQLRSELGSENVLYIHLTLVPYLAAAGEVKTKPTQHSVKELRSIGIHPDIILCRSEVDLDEDIKRKIALFCDVDRDAVFTAVDVKSIYQLPLSFYNEGLDQKIAIMLKLPAKNCNLESWRKLNHTLENPTGETTIGIVGKYVDLKEAYKSLHEALIHGGVANEVKVNLRYVNSEEITPENVKEKLAGCDGVLVPGGFGNRGVEGKITAIQYARENKVPFFGICLGMQCAVIEYARNVMGLKGANSEEFNPEGDDNVIYLMKEWYDYRTKKTENRCEESDKGGTMRLGAYPCKVVEGTKAMAAYGKTEIQERHRHRYEFNKEKFADQLVEAGLVLSGLSPDEALVEIVEVADHPWFLGCQFHPEFKSNPMHAHPLFRDFIKASCENKNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DUS29_MOUSE
Sequence: MASGDTKTSVKHAHLCAERLSVREEEGDAEDYCTPGAFELERLFWKGSPQYTHVNEVWPRLHIGDEATALDRYGLQKAGFTHVLNAAHGRWNVDTGPDYYRDMAIEYHGVEADDVPTFDLSIFFYSAAAFIDSALRDDHSKILVHCAMGRSRSATLVLAYLMIHKNMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQLVKQRRQAGPGDSDLGL
What is the function of this protein?
Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity).  Involved in the modulation of intracellular signaling cascades.  In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase (PubMed:30201684).  Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (PubMed:32639872).
What are the official names of this protein?
Dual specificity phosphatase 29, Dual specificity phosphatase DUPD1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSMG_CAMJJ
Sequence: MIFKDYDFLQNYDLKNFEEKVKIYKELLSKFNRIHNLTHLKNIDENIFDSIKILDFYDFSKAKNIADIGSGAGFPAVFLAFLLQSNFHLFEPNPKKAAFLRTLKIECELPNLHIYKEKVQEYKNTFKADIITSRALMDVKPLLEICKNLKDENTVFILWKGSEIYQELENIKDYEIFENNLRRYCILK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESCO1_MOUSE
Sequence: MSIQEKSKENSSIVTKESEDENLEEEVESSQNSPTKKSGSKEAVKTPVRFSNKSKTNESEFGMRMSTRSASCSADKTATNSFNKNTVTLKGQSQESSKTKKLCQEKLSLGILKGNEQLHRRSQRLQQLTECTTRSLRSREIHGQIQTVKQNQQSARREQCNSTQSKCNKVKVNQKHVKRKVLEIKSDCKEDRHSVTNEVINSPKGKKRKVQHQTTSTCSSQCNQGSEKCLQKTSRKEEIKPVPVTADIRKLKAATSVVSKKNELRKSAHTQVSTSTKRPQIPLPLVPEHSDDQELEQAGKSKRGSILQLCEEIAGEIESDTVEVKKESSCVESVKEEKPAEVKLQGTDAERQILHHKEANQDVRSNRFFPSRKTKPVKCVLNGINSSTKKNSNWTKIKLSKFNSVQQHKLDSQVSPKLNLLQTGLSTSVLEMPHPVSQSTFLEMKAHGNVTCQRDKMKGIKSEEVKINNIAIEINKATKRDPGNCNLDNHIKPSPDSSLDNQMKLSCESAPDQNFSICSASEVETNPLENTAAASTLLSQAKIDEDRTFPGSAPNQQHSVLSDEASINRKNRDVPPNHSQLKHDSHLEITIPKSLKLKDSEKVDEKQLVIDAGHKRFGAVSCNICGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNTT
What is the function of this protein?
Acetyltransferase required for the establishment of sister chromatid cohesion.  Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together.  In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase.  Acts by mediating the acetylation of cohesin component SMC3.
What are the official names of this protein?
N-acetyltransferase ESCO1, Establishment of cohesion 1 homolog 1, ECO1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ECO subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Nuclear at interphase, associated with chromosomes during mitosis.
Protein: ACP_DESAH
Sequence: MSVEAKVKKIIAEKLQGVDIEDVIPEASLVDDLGADSLALVELIMSMEEAFDIDIDDDDAEKMITVNDAIEYIRKKS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2B_ORYSJ
Sequence: MQEPKHTDPAAMRGAHHRRARSEVAFRLPDDLDLGGGGAGAFDEIGSEDDLFSTFMDIEKISSGPAAAGGSDRDRAAETSSPPRPKHRHSSSVDGSGFFAAARKDAAASLAEVMEAKKAMTPEQLSELAAIDPKRAKRILANRQSAARSKERKARYITELERKVQTLQTEATTLSAQLTLFQRDTTGLSAENAELKIRLQAMEQQAQLRDALNDALKQELERLKLATGEMTNSNETYSMGLQHVPYNTPFFPLAQHNAARQNGGTQLPPQFQPPRPNVPNHMLSHPNGLQDIMQQDPLGRLQGLDISKGPLVVKSESSSISASESSSTF
What is the function of this protein?
Transcription factor probably involved in vascular development and shoot tissue organization.  Binds to the DNA sequence 5'-CCGAGTGTGCCCCTGG-3' present in the promoter region Box II of the phloem-specific rice tungro bacilliform virus (RTBV) promoter.  May regulate tissue-specific expression of the RTBV promoter and virus replication.
What are the official names of this protein?
Transcription factor RF2b.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
Protein: MUTL_BACMK
Sequence: MGKIRKLDDQLSNLIAAGEVVERPASVVKELVENSIDANSTSIEIHLEEAGLSKIRIIDNGDGIAEEDCIVAFERHATSKIKDENDLFRIRTLGFRGEALPSIASVSELELITSTGDAPGTHLSIKGGDIIKQEKTASRKGTDITVQNLFFNTPARLKYMKTIHTELGNITDIVYRIAMSHPEVSLKLFHNEKKLLHTSGNGDVRQVLASIYSIQVAKKLIPIEAESLDFTIKGYVTLPEVTRASRNYMSTIVNGRYVRNFVLMKAIQQGYHTLLPIGRYPIGFLSIEMDPMLVDVNVHPAKLEVRFSKEQELLKLIEETLQSAFKKIQLIPDAGVTTKKKEKDESVQEQFKFEHTKPRESSMPNIVLPTGMDEKQEETTTVKQPAQLWQPPKQEWQPPQSLVREEQSWQPSSKPETVREEKEWTSNDDDFELEELEEEVGEIEEIEMNGNDLPPLYPIGQMHGTYIFAQNDNGLYMIDQHAAQERINYEYFRDKVGRVTQEVQELLVPYRIDLSLTEFLRVEEQLEELKKVGLFLEQFGHQSFIVRSHPTWFPKGQETEIIDEMMEQVVKLKKVDIKKLREEAAIMMSCKASIKANQYLTNDQIFALLEELRTTTNPYTCPHGRPILVHHSTYELEKMFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: TRMD_STAAM
Sequence: MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNEDKQILERYKIGLKKG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_GUITH
Sequence: MFNVQFDIFNFSNNITFLTLLISLISYWLGLIFKKIKNVFYIGYGSTILACITITIILGTRWIESGYFPLSNLYESLMFLTWGLLFSAIYLEYKTNLYLIGAIVSPISLFIVSFSTLSLPQDMQKAAPLVPALKSNWLMMHVSVMMLSYSTLIIGSLLAILYLVLIKAQQKKHSLKDFAFANLEFTFPKSTNSTNFNLLETLDNLSYRTIGFGFPLLTIGIIAGAVWANEAWGTYWSWDPKETWALITWLVFAAYLHARITKSWTGERPAYLAALGFVVVWICYLGVNFLGKGLHSYGWLN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DER_PASMU
Sequence: MTTPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQANIAGYDFIVIDTGGIDGTEEGVEEKMAEQSLLAIEEADVVLFLVDARAGLTSADIGIANYLRQRQNKITVVVANKTDGIDADSHCAEFYQLGLGEVEQIAASQGRGVSALMEQVLAPIAEKMNAESPEQSAVENTDVSETGEQDEWDHDFDFANEEDTALLDDAIAEELEAQDKNIKIAIVGRPNVGKSTLTNRILGEDRVVVYDLPGTTRDSIYIPMERDGQHYTIIDTAGVRKRGKVHLAVEKFSVIKTLQAIQDANVVLLTIDAREGVSDQDLSLLGFILNAGRSLVIVVNKWDGLNQDIKDQVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSIQEAYACATQKMTTSMLTRILQMATDEHQPPMMGGRRIKLKYAHPGGYNPPIIVVHGNQMDKLPDSYKRYLSNYYRRSLKIIGSPIRLLFQEGNNPFAGKRNKLTPNQLRKRKRLMKFIKKSKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: FADI_SALPA
Sequence: MRQALPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARSEIPADAIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKALARVLVDVNKARTTRQRLTLFSRLRLRDLLPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWAEGKLAEEVMTTYVPPYKNPFAEDNNIRGASTLADYAKLRPAFDRKHGSVTAANSTPLTDGAAAVILMTESRAKELGLHPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMADLTLFDMHEAFAAQTLANLQLLGSERFAREVLGRAQATGEVDDAKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_CLOBB
Sequence: MIDLCVLGTTGGMPMVDKYLSATLININGRKILIDCGEGTQVAMRKIGWGFKSVDLICITHSHGDHTIGLPGLISIMGNSGRTEKVTVVGPKGIKEIVNGLNVINPYLPYELEIIELENNDLKFIIDKNNMSLCEDNNKCNLILSSLEVEHSAKCLSYSFYIKRRPRFSVEKASKNNVPKPLWSKLQNQEIINYDNKIYTPDLVLDNARKGIKISYVTDTRPISAIPEFIKYSDLFICEGTYGSDEDIDKAIKNKHMTFRESATLALNGECKELILTHFSPALSEPESFVDNAKQVFHNSSVAYDGLIKTLKFID
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: MUTT_BACSU
Sequence: MYTQGAFVIVLNESQQILLVKRKDVPLWDLPGGRVDPGESAEEAAVREILEETGYNAALSAKIGVYQRPKFQDEQHLFFGSITGGQAMADGTETAGLKWVSPGRLPLFMVPNRKRQINDFKNGAQDVNVTVKDSGLLAAIDLLKRRLGK
What is the function of this protein?
May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool.  8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions.  MutT specifically degrades 8-oxo-dGTP to the monophosphate (By similarity).  Functions, in conjunction with ytkD, to protect vegetatively growing cells from DNA-damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide).  The 2 proteins do not however protect spores.
What are the official names of this protein?
Putative 8-oxo-dGTP diphosphatase, 8-oxo-dGTPase, 7,8-dihydro-8-oxoguanine-triphosphatase, Mutator protein MutT, dGTP pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: RL4_STRPJ
Sequence: MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGNEFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: VE1_HPV26
Sequence: MDCEGTNEEGRGCTGWFSVEAIVEKHTGDTISDDETDNSSDTGSDLIGFIDDSSISDYAEQEVTQALFQAQQKQANTKAVRNLKRKLLGSQNSPLQDITNQHRQQSDSQQNTHQVNNSQAKRRAVDSVPDSGYGYTEVETLTPVQVDKQYEENGGLPSVCSQGGSNASVEDIDVDTHVNSVTQICELLKCSNVKAALLSKFKTVYGVSFAELVRVFKSDKTCCSDWVCAAFGVAGSVAESIKSLIQQYCLYYHIQCLTCNWGVIVLMLVRFTCAKNRTTIKNCLCMLLNVPETQLLIEPPKLRSTAVALYFYKTGLSNISETYGDTPEWIVRQTQLEHSFDDATFDLSKMVQWAFDHDITDDSEIAFKYAQLADIDSNAAAFLKSNCQAKYVKDCATMTRHYKRAQKRSMCMSQWLQYRCSKIEEGGSWKEIAKFLRFQHVNFIYFLQVLKQFLKGTPKHNCIVIYGPPNTGKSQFAMSFIKFMQGSVISYVNSNSHFWLQPLEDAKVAVLDDATYSCWLYIDKYLRNFLDGNPCCIDRKHRSLLQVTCPPLIITSNINPQEDNSLLYLHSRVTVIPFPNTFPFDSNGNPVYALTDVNWKSFFSTTWSRLDLEEDADKENGEPLPAFKCVPGENTRLL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: AGUA_VIBPA
Sequence: MKLSTTPAQDGFYFPAEFQPVSEVWLAWPERKDNWRDDALPAQETFARIANLIAEVTKVCVAVCSHNFDRARQMLHSDVRLVEIPFNDAWMRDIGPTVLVNQAGERRGISWQFNAWGGEYNGLYDNWQQDDLVAGSVCDIIGIDYYRAPFVLEGGAIHTDGEGTLYTTEECLLSPGRNPQLSKAQIEEQLKVYLGIEKIIWLPNGLFNDETDGHVDNLMHVIAPGKVVLSWTDDPSDPQYALSRQAEQVLKSQHDAKGREIEIVRLPLPGPLHYSEREANGIDASSGMSRQAGERLSASYANFLIVNGHVFLPMLDEDTDAIAIDILQNAMPEYQIIAIPSREVLLGGGNIHCITQQIPA
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: MP_MSVSE
Sequence: MDPQSAIYTLPRVPTAAPTTGGVSWSHVGEVAILSFVALICIYLLYLWVLRDLILVLKARRGRSTEELIFGSEAVDRRHPIPNTLEPTAPVHPGPFVPGQG
What is the function of this protein?
Involved in the viral transport within, and between cells.
What are the official names of this protein?
Movement protein, MP.
What is the protein family that this protein belongs to?
Belongs to the mastrevirus movement protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: Y669_CUPNH
Sequence: MIKWLQRAGCLSAHAVVPQAPAAASVQGRHDLAFDTISNARDLGGLAGAGGRRVRQGRLYRSGNPALASAADLERLQTLGLDMVVDFRSPGEKSPEEAAFGQRFHWVAAPVLEGSMAMDVLMPRLRASTPAQMDAFMLEVYGDFPVRYREAFAGFMRTAQGGKTLLFHCTAGKDRTGFAALLLLAALGVAQDDILANYLESNQRNAQFNQTALARMAGLGVAPAVMTPLLEVRASYLDASMRAIDAGWGSVDNYLRDALEVDVAQLRGHYLAG
What are the official names of this protein?
Putative tyrosine-protein phosphatase H16_A0669.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: ASB14_HUMAN
Sequence: MDNYTSDEDIDEDFDTQLIIQQSLQDIYKPGTAQHAPKDESLHSFLSADYKKIVETIEKVGKEDALSHLTKYHSAFGEADEIGWIPLHKAAVQLNRKILEITLSASDPSLWEQTTHNGETPLFLAVSSCLLENATFLLLNGCNPNAKNFEGNSPLLAAVLRDCYDMAALLINYGADVNLRCANERTALHEAAKLGREDMVKLMLVSGAHPDPQSTYGFTPLALAAQSGHTEIMEMLLRKGKIFCLASDSSSILLEAASGGNPDAVALLLEYGADANIPKNSGHLPIHVAADRGHLLALKILIPVTDLAAIKQSGISPVHCAAAGAHPQCLELLIQAGFDVNFMLDQRINKHYDDHRKSALYFAVSNSDLSSVKLLLSAGALPNQDPVNCLQIALRMGNYELISLLLRHGANVNYFCRVNPLHFPSALQYTLKDEVMLRMLLNYGYDTERCFDCPHGDKVHPSYTVEGWTSTVIKDTKFCEVITLSWLQHLSGKVVRVMLDYVDQVRICSKLKAVLQKQGIWSEIHFILTNPRSLKHLCRLKIRKCMGRLHLRCPVFMSFLPLPNRLKAYVLYKEYDLYGQGIFTGTW
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 14, ASB-14.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: FUCD_XANCP
Sequence: MRTIIALETHDVRFPTSRELDGSDAMNPDPDYSAAYVVLRTDGAEDLAGYGLVFTIGRGNDVQTAAVAALAEHVVGLSVDKVIADLGAFARRLTNDSQLRWLGPEKGVMHMAIGAVINAAWDLAARAANKPLWRFIAELTPEQLVDTIDFRYLSDALTRDEALAILRDAQPQRAARTATLIEQGYPAYTTSPGWLGYSDEKLVRLAKEAVADGFRTIKLKVGANVQDDIRRCRLARAAIGPDIAMAVDANQRWDVGPAIDWMRQLAEFDIAWIEEPTSPDDVLGHAAIRQGITPVPVSTGEHTQNRVVFKQLLQAGAVDLIQIDAARVGGVNENLAILLLAAKFGVRVFPHAGGVGLCELVQHLAMADFVAITGKMEDRAIEFVDHLHQHFLDPVRIQHGRYLAPEVPGFSAEMHPASIAEFSYPDGRFWVEDLAASKAKA
What is the function of this protein?
Plays a role in the catabolism of L-fucose.  Catalyzes the dehydration of L-fuconate to 2-keto-3-deoxy-L-fuconate by the abstraction of the 2-proton to generate an enediolate intermediate that is stabilized by the magnesium ion.  L-fuconate is the preferred substrate with 15-fold lower activity observed for L-galactonate and 8-fold lower activity with D-arabinonate.  No activity detected with D-fuconate.  Can also catalyze the epimerization of L-talonate and D-ribonate, but at slow rates.
What are the official names of this protein?
L-fuconate dehydratase, FucD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: MSHD_TSUPD
Sequence: MAEVVHGPVADPGAVLALVAEAQAADGIGPLSEQFRLGVAGPGPHVVAEGGYAGIVIPPAGGPGAVEAVVAPSHRGRGLGRELVATALDVAGAGATVWAHGDLTPARAVAARLGLTPVRTLLNLRRPLADLDPAPSAPDGVTVRTYAGPADDTALLAVNNAAFAWHPEQGGWGPEQIAERTGADWFDPAGLFLAIGSGSGSDEADGRLLGFHWTKVADPATGLGEVYVVAVAPEGQGRGLGRLLTSVGLHYLADRKLDTVELYVEGDNAAALHTYTKLGFSEHERHVAYAHS
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: GRXS2_ARATH
Sequence: MDMITKMVMERPVVIYSKSSCCMSHTIKTLLCDFGANPAVYELDEISRGREIEQALLRLGCSPAVPGVFIGGELVGGANEVMSLHLNGSLIPMLKRAGALWV
What is the function of this protein?
May only reduce GSH-thiol disulfides, but not protein disulfides.
What are the official names of this protein?
Monothiol glutaredoxin-S2, AtGrxS2, Protein ROXY 10.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPC_PSEPK
Sequence: MTAYLRPALSLALLMTLVTGALYPLAVTGIAQVAFPNQANGSLVRDAQGQVRGSALIAQDFQGDGWFHSRPSAGAYATVASGASNLSPSNPALAERVKGDAATLYQAQQGPVPQALLTTSGSGLDPHLPPEALAYQIPRVAAARQLPVERLQALLEQATLHPLIGPPVVNVLALNQALEKLAIVR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: C3H36_ARATH
Sequence: MDTRKRGRPEAGSFNSNGGGYKKSKQEMESYSTGLGSKSKPCTKFFSTSGCPFGENCHFLHYVPGGYNAVSQMTNMGPPIPQVSRNMQGSGNGGRFSGRGESGPGHVSNFGDSATARFSVDASLAGAIIGKGGVSSKQICRQTGVKLSIQDHERDPNLKNIVLEGTLEQISEASAMVKDLIGRLNSAAKKPPGGGLGGGGGMGSEGKPHPGSNFKTKICERFSKGNCTFGDRCHFAHGEAELRKSGIV
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 36, AtC3H36.
Protein: VHR2_YEAST
Sequence: MIDDTENSKIHLEGSHKTGKYTGYGTTHKIRAQLNFNDEKKWKKFSSRRLELIDSFGLSQHKASEQDDNIRQIATILRSEFEYPDTFSAEFEKLVTAAVQSVRRNRKRSKKKLLDSKKKIARGKVQKIPLSPPSSSNMGSCSASNASSSDEEASVKEEPAEHALPSLNTITSQKLLPYPNGRTLPPVPTQVRSLLKKNASLLRDPSAPYAHGGDEKLQKFDIEDQPLESEQEYDFIAKSIIVEIVNNAIPLPEQIQRDKFIRPNLTKKKGCQSKVVISNNLRKLILSKIHNSRTCLEMSKDERNLDSFANLETLGKNSLMASISLVVENSFSHLPSSTKQYLTERLSSIEFLTILSQRLFMPATRQLFADLSQEKIQVRVLNLILGSLVKDYGFDASLAPINEIIYHMTLHQYPLVCSNKQSNPMRPHSTSEVLSAHSSTKDASTPGKEEPRVTRSSTSADSTIITLPSIEVPNTYDDDRLKMLSAISLQIENSTFSKPFSTISK
What is the function of this protein?
Transcription factor that regulates ERG9, but seems to have a more global function in transcription.
What are the official names of this protein?
Transcription factor VHR2, VHT1 regulator 2.
What is the protein family that this protein belongs to?
Belongs to the VHR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_NOCFA
Sequence: MIDLRLLREDPDAVRASQRARGEDPALVDALLEADAARRAAVATADNLRAEQKAMSKQIGKAPKEERSALLARAQELSVKVKEAEAAQHAADADLDAAHRALSNVVLPAVPAGGEDDYVVLETVGTPPEFDFEPKDHLELGEALGLMDMERGAKVSGSRFYFLTGHGALLQLGLLQLAAQKAVANGFTMMIPPVLVRPEVMAGTGFLGRHAAEVYHLADDDMYLVGTSEVPLAGYHADEILDLSAGPKRYAGWSSCFRREAGSYGKDTRGIIRVHQFDKVEMFVYTTPDQAEAEHERLLAWEREMLAAIEVPYRIIDVAAGDLGSSAARKFDCEAWVPSQQTYRELTSTSNCTTFQARRLSVRYRDENGKPQIAATLNGTLATTRWIVAILENHQRADGSVRVPAALVPFVGTDVLRPPA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_STRGC
Sequence: MKTKEVVDDITMNRAITRITYEIIERNKELNQVVLAGIKTRGVHLAHRIQKRLAQLEQIDIPVAEIDTKPFRDDKKSQEADSTLIPVDITDRQVILIDDVLYTGRTIRAAIDNLVSHGRPSRVSLAVLVDRGHRELPIRTDYIGKNIPTSRTEEIIVEMTETDGQDRILIKGE
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.