PharMolix/UniProtQA huggingface dataset:
Protein: GREA_CHLMU
Sequence: MDYLEKLQSLMENHPSDFFSLWEEYCFNDVVSGDELIVLLEKIKSSSIAPAFGKIAESVIPLWEQLPESEEKDKVLSLVFDIQTTNSKRLLELALQQVKKYEDSPNYKEALRIVGLRDGIFFTHCLRHFALLMHLCEGNFVFHQGGWGVGEIMGVSFLQQKVLVEFEGVLTAKDISFETAFRMLSPLKKDHFLARRFGDPDAFEAFARKDPVAVIECLLKDLGPKNAKEIRNELVGLVIPEEDWSRWWQSAKIKMKKDSHILAPTSSKDPYIFDPKGFSFISQLQASLSGSNDASKKIASCYTFVRDLGSELKDEANRQFVIKELKSLDLPADSALSIQRAMLLSEFLGDKSSELDCENIAKLSEDQMFDIVNHIEILSFQKSFLSLIHSCSPAWVSVFTKILLTTSTSILRDQVFKALIVDKKARESILEKVSAMIEQPLLYPELFVWLFLRVVSGEDGLFSESDRKEIGRQMLASALEFMHKVAGSPQKDLGKKLYSFLVGQRFLAIRQIIENASIDYLKEFVLLSSKCPQFTQGDLGVLRSLAEVVQPALKRRVAEEENILWTTSESFTRMKAKLQSLIGKEMVDNAKEIEDARALGDLRENSEYKFALERRARLQEEIRVLSEEINRAKILTKDAVFTNSVGVGCKVVLEDEQGEEDCYTILGPWDANPEEKILSLKSKLAQEMVGKTVGESVLFQGKKHKIKQISSIWD
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides (By similarity).
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: P4HA1_CAEEL
Sequence: MRLALLVLATIGYAVADLFTSIADMQNLLETERNIPKILDKYIHDEEERLVQLKKLSEEYSKKNEISIENGLKDITNPINAFLLIKRKIFDWKEIESKMNANKAGNVVSSITDDSYGVRYPTADDLSGAAIGLLRLQDTYRLDTKDLADGKIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVMWMEEAQRRLGDEVEPTVEVEDILEYLAFALYKQNNLKHALKLTEELYKMNPTHPRAKGNVKWYEDLLEQEGVRRSDMRKNLPPIQNRRPDSVLGNTERTMYEALCRNEVPVSQKDISRLYCYYKRDRPFLVYAPIKVEIKRFNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLKEWEGDVVETVNKRIGYMTNLEMETAEELQIANYGIGGHYDPHFDHAKKEESKSFESLGTGNRIATVLFYMSQPSHGGGTVFTEAKSTILPTKNDALFWYNLYKQGDGNPDTRHAACPVLVGIKWVSNKWIHEKGNEFRRPCGLKSSDYERFVGDLGYGPEPRNAPNVSPNLAKDVWETL
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
What are the official names of this protein?
Prolyl 4-hydroxylase subunit alpha-1, 4-PH alpha-1, Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1, Protein dumpy-18.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: FOLD_STRA5
Sequence: MTELIDGKALSQKMQAELGRKVERLKEQHGIIPGLAVILVGDNPASQVYVRNKERSALEAGFKSETLRLSESISQEELIDIIHQYNEDKSIHGILVQLPLPQHINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPMMVPCTPAGIMEMFREYHVDLEGKHAVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRNLSEVTKEADILIVAIGQGHFVTKDFVKEGAVVIDVGMNRDENGKLIGDVVFEQVAEVASMITPVPGGVGPMTITMLLEQTYQAALRSVSL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DEOD_ECO81
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGVDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: KDPA_METCA
Sequence: MTANGLLQICGYLGVLLALAKPLGSYMAAVYEGRSATVRVLASVERFIYRITGIDPEAEMRWTGYASAFLVFNLLGVLAVYALQRCQGFLPLNPQGLPAVAPDSAFNTAISFATNTNWQGYGGEMTLSHLTQMLGLTVQNFVSAASGMAVLVALIRGFVRRNADTLGNFWVDLTRSILHILLPLSFLLALLLIGQGVVQTFEPYRNVTLVEATGYDRPKQDEGGHPLVDADGNPVTEHVTVSEQTLALGPAASQVAIKQLGTNGGGFFSVNSAHPFENPTPFSNFLEMLAILVISGALCHTFGVMVGDTRQGWVILAAMTLIFVPLLFVTVLCEQGGNPAFAALGVDPAGGNMEGKETRFGIVNSALWATATTAASNGSVNAMHDSFTPLGGLVPMWLMQLGEVVFGGVGSGLYGMLVFAIVAVFVAGLMIGRTPEYLGKKIEAYEMKMAAIVILVPPLMVLGGTAVAVMLDAGKSSVFNPGAHGFSEILYAFSSAGNNNGSAFAGLAANTPFYNLMLGLAMWFSRYWLAVPVLAIAGALAAKNYVPPGAGTLPTHTPMFVGLLVGVVIIVGALTFIPALALGPIVEHLMMIGAR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: V7_SPTNK
Sequence: MSVSSLLQPNTYNINSKSQSLSNTPSNPTSQTNTLWSNNAYNPPHLMFGSSDLNNGTGPSGPKGDKGDPGSKGETGSQGIKGDPGVKGTTGGTIGSGTYFSGDLPSYVTTGGTETSIPEVSTGTVSFTTKTLGGNCNYSSGVFTTTETAAFYVAVTYIGTSVGSLSGSLTLSIFKNGGTAVYNTLVSYSGAGIQMSASLNGIIEMTPSDNIFIGFVNSGGEIQPNASGFTLNIFRI
What are the official names of this protein?
Uncharacterized protein V7.
What is the protein family that this protein belongs to?
Belongs to the sputnik virus V6 family.
Protein: DLS1_YEAST
Sequence: MNNETSGKETASAPLCSPKLPVEKVQRIAKNDPEYMDTSDDAFVATAFATEFFVQVLTHESLHRQQQQQQQQVPPLPDELTLSYDDISAAIVHSSDGHLQFLNDVIPTTKNLRLLVEENRVRYTTSVMPPNEVYSAYVVNDTAPKPNIVEIDLDNDEDDDEDVTDQE
What is the function of this protein?
Functions as component of the ISW2 complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA.  The ISW2 complex is involved in coordinating transcriptional repression and in inheritance of telomeric silencing.  It is involved in repression of MAT a-specific genes, INO1, and early meiotic genes during mitotic growth dependent upon transcription factor UME6 and in a parallel pathway to the RPD3-SIN3 histone deacetylase complex.  DLS1 is partially required for the ISW2 complex chromatin remodeling activity and is not required for its interaction with chromatin.
What are the official names of this protein?
Protein DLS1, DPB3-like subunit of ISW2 complex 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ITM2B_CHICK
Sequence: MVKVSFNSALAHKEAANKEEENSQVLILPPDAKEPEDVVVPAGHKRAWCWCMCFGLAFMLAGVILGGAYLYKYFAFQQGGVYFCGIKYIEDGLSLPESGAQLKSARYHTIEQNIQILEEEDVEFISVPVPEFADSDPADIVHDFHRRLTAYLDLSLDKCYVIPLNTSVVMPPKNFLELLINIKAGTYLPQSYLIHEQMIVTDRIENVDQLGFFIYRLCRGKETYKLQRKEAMKGIQKREAVNCRKIRHFENRFAMETLICEQ
What is the function of this protein?
Plays a role in the induction of neurite outgrowth.
What are the official names of this protein?
Integral membrane protein 2B, Transmembrane protein E3-16.
What is the protein family that this protein belongs to?
Belongs to the ITM2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: CITX_STRPG
Sequence: MSKEAYFSGESIQLSDMLRAREERALRQLHLLKEYPEGSLLSVTMNIPGPIKTSPKLLEAFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDLKLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLRKHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG
What is the function of this protein?
Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.
What are the official names of this protein?
Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, Apo-ACP nucleodityltransferase, Holo-ACP synthase, Holo-citrate lyase synthase.
What is the protein family that this protein belongs to?
Belongs to the CitX family.
Protein: PLSY_BRADU
Sequence: MGLEAFLPVALVIGYLLGSIPFGLVLTRLAGTQDIRSIGSGSIGATNVLRTGRKSLAAGTLLLDALKGTVAVVIAGYIAGPNAAMAAGLGAFLGHLFPVWLKFKGGKGVAVYIGILLGLFWPAAVVFCLLWLATAFTTRYSSLSALVASFITPMFLWWFGHLALSALFAVLTLLLFYAHRENIKRLQSGKESRIGEKA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_SALPC
Sequence: MDKKSARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PPDK_RICTY
Sequence: MNKLIYYFGNNGSDGNASMKNILGNKGAGLAEMSNLKLPIPNGFTITTELCNYFYKHNNNLPKNFQNELQQAITKLEITTGKIFGSTTSNPLLLSVRSGSTVSMPGMMDTILNLGMNNEVCNALADSCGNKLFALDSYRRFLEMYGSTVLSIPSDLFEQIYEKHKVQADIYKDSDITVELLEKIIDDFKRLHIKYTKQLIKDPYEQLESAIKAVLYSWKNNRAIVYRKLNNISEDFGTAINIQEMVFGNLGKTSATGVVFTRSPSTGEKKLFGEFLINAQGEDIVSGTRTPMPIIANDSNSMQAMMPEVFTKLSQIAKKLEEHYLDMQDIEFTIENNKLYILQTRTAKRTAIAAINIAVQMVEEKLISKEQALMRIDPESLNQLLHTRIDYSKKLTAIAEGLPASPGAATGIVVFSPYDAEKLSHHHKVILVRHDTSPEDINGMHVASGILTIRGGMTSHAAVVARGMGKPCVCGTNNLSIDEQKQILIAGDIVIKQGDIITIDGGSGKIFLGEMPLIQPTFSEESTLILDWADEISSLKVRANAETVNDALVSIKFGAQGIGLCRSEHMFFDKNKIPLVREMIIAPDIERRQCALQKLLPLQTEDFKALFRVMKNKPVNIRLLDPPLHEFLPTTDEDKKNLAHSLNLPLSMIHQRLHAMHEVNPMLGHRGCRLGICLPEIYQMQIEAILTAIFELHKKEHIESNLELMIPLISNVAEIKKLKMDIYAVVKKLEQRYSYKFSFTLGTMIELPRAALGSKKIAKEVDYFSFGTNDLTQTTYGISRDDIASFLPYYLEEKIFESDPFTTLDEEGVGELIKIAIKRGKSSNANLKLGACGEHAGNPTSIAFFHKMNLNYVSCSPYRIPIARIAAAQAKIKQGS
What is the function of this protein?
Catalyzes the reversible phosphorylation of pyruvate and phosphate.
What are the official names of this protein?
Pyruvate, phosphate dikinase, Pyruvate, orthophosphate dikinase.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: CRCB_PARP8
Sequence: MYLSILAVGIGGALGSLFRWFLGLRLNALFPALPLGTLASNVIAGYIIGAAVAYFGRNPQIAPEWRLFIITGLMGGLSTFSTFSAEVVQHLQQGRLNWAAGEIAIHVTASVIATVLGITTVAVVTR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LCL2_BOTFB
Sequence: MAKVLFSLFSFLFLIIGVSAQFQFFEQMFNGQQQQHQRQPQDVPSDSQWYQDNYDRAHCTSYLCPGTLSCVAFPHHCPCAHPTYEEKFELADGNAICISKGGFKAGEAARKVELARKGLI
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: PHNC_BURPS
Sequence: MDAIRIERLSKTFPNGRKGLEDIDLAIAPGEMVALIGASGSGKSTLLRQIASFSSSDARPSRIDIFGRSIQRDGRIARDVRRMRRDIGFVFQQFNLVDRLSVETNVLIGALARVPMWRRLAGRFSRADRALAAQALGEVGIAEHARERAANLSGGQQQRAALARALVQRARIILADEPIASLDPAASRRVMEMLRALNANHRLTVLVSLHQIDVALRFCPRVVALRAGRIVYDGPSAALTRERLHALYGDDAHLPFAVGDEVRPAAREAAGEPARRAPAAFDSAGSPDLPDSQPASPRRMLAASSMR
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNA14_GIBZE
Sequence: MASEGTSWGAEDIGAQGDQVQHSEEQVDNYAHDSLASGDADAADNGTEDDGGEYDPESVTIGTPAMVPEPASSGTQRQTSKPKMSGGFIVEASDDEDEDEDEDEDEDEDEQPASAVPQTDAVSTQNHPGPSTTSDEHVPAAPTHAPVPPAVPSNVTPVLPGFGPVDLLEFRVKEDPRGDMDAWQELIASHRDFSPLEKARSTYNRFVEIFPQAADKWVEWIELELKYNNFVEVEQLFGRCLMQVPNVKLWTVYLDYIRRRNDLNNDPSGQARRTVTQSYEFVIDNIGVDRDSGNIWQQYVQFVKNGPGQIDGTDWQDRQKMDQLRGIYRRAVAVPMSTVNNLWKEYDQFEMGLNKMTGRKFIQERSPVYMSAKSANIALDNITRHLDRTNLPRLPPAPGFNGDQEFRDQVEMWKKWIAWEKEDPLVLKSDEPKAYNQRVLHVYKQALMALRFWPEIWVDAAEWCFQNDIRENDKEMGTELLVEGIKANRESVLLALKHADHIEVNYPDKEVDKAEFAQAVRKPYDDVLETLYEMGDKVKEREKLEISTLKQAAAQDPVQTSIEENDDDEDNTPKRSPTEERILAIQKGYAAETQLLSRTISYVWIALARAMRRIQGKGSQAEGGLRKVFTDARQKGRLTSDVYVAVALLESVVYKDPVGAKIFERGARLFPNDEMFMIEYLKYLHSKDDTTNARVVFETCINRLVSNPDTLAKAKLLYAYFHKYESQYGELSQISKLEDRMAELFPEDPKLKSFVDRFSTEKFDPIATPIIISKTAQMRPKQIVPVVQHQHQQSISLRNSPMPVRQEQNPRPQYVRATASPKRPLAVDDEELNPPKRLARGASPLKGAAGRRLDQQRRNQASALHRDITFLLNILPSSQSYDAQRFNSAALVSILRDTEIPDFATLKAAGGGQPRFGNPTHTRQPSGEFVNRPLSPYGRMSAAAGGYRNSPLRPETGNAYQSNPYPPPEASGQQPTWPQAPGGYGAPAPGQFGGYRY
What is the function of this protein?
Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA 3'-end-processing protein RNA14.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleus and/or cytoplasm.
Protein: NOL6_XENLA
Sequence: MQKKRSRAGAAEQEAASDDGEMSDSSDKMEVSQNKGKSGIKRAPEADDVLRPVKLSKSDLYKPPTNDELNRLKETENLFHTNLLRMQIEELLQEVKLKEKRRKTIDGFLHEINALLGTIPETPKTDLTDQSWLSSSIKVPFLQVPYQVKGKFSFLPPSSIKVVGSYLLGTCIKPEINVDLAVTMPQEILQVKDNLNQRYSRKRALYLAHIASHLTDNKLFSSVKFTYMNSNHLKPILLLRPQGKDEKLVTVRIHICPPPGFFKLSRLYPNKNNVRTSWYTEQQTETEGVCDPPTPYYNNTILSDLTLEHHLHHLTNCATDFPGMKDAIALLKVWLHQRQLDKGFGCFNGFLASMLISYLLSKNKINKVMSGYQVLRNTLQFLATTDLTVNGITMATCSDSSLPSLPDFHEAFQVVFVDPMGVVNLCADMTASKYRQIQFEASESLKVLDDTNVNGFHLLLMVPKPFVRTFDHVFHLTNVAKLQGTCKKMKLLNQLIDRGGDYLATALPYLLSVLSKGLGPRVSLLSHTLTHKPEWNVGEEPAKHKDSGLVTVGLLLDPELYTNVLDKGPAADSSEALDFRAFWGEKSELRRFQDGSICEAVVWTGGSLYDKRKVPELIVKYLLELHANIPESCINYTGNALDCVLSRGRETSTEEEKMVSIIQSYDDLSRKLWNLNDLPLTITSVQGTHPCLRYTDVFPPLPVKPDWSSYHLLREKKCLIPNPEKPCPAYVSPVKVICHMEGSGKWPQDKDAIKRLKAAFQIRLSELLSSQHQLLCNPSATHTDVYKDGYVFRVQVAYHREPQYMKEFVTPEGMLKYQDTEESMQLEMETNHLPHLSSTLHGLHQQHPAFGGTSRLAKRWIQSQLLGDSFSEECLDLLVAHLFLHPAPYSPPSSALVGFLRFLHLVATFDWKNSPLIVNLNGELKGSEYTEIQNDFISARAQLPVMFIATPKDKKDSVWTKNQPTAQMLQRLIVLCLESLRALEQQLMDPRGNHDYKMIFRPPLDLYDVLIRLNPKQISRHREAVDQPAKSFFRGMLKEGAQVKDLMFPVVGYDPIQLFLQELREAYGEFALFFHDLHGGDVIGVLWKPSSFEPQPFKTTNVKGRQMDGKSDKALLVPNAEAFVEDLEILGEGLVAGVEAQTERWNI
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Nucleolar protein 6.
What is the protein family that this protein belongs to?
Belongs to the NRAP family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GLRX1_SALTY
Sequence: MFTVIFGRPGCPYCVRAKELAEKLSKERDDFNYRYIDIHAEGITKADLEKTVGKPVETVPQIFVDQKHIGGCTDFEAWAKENLNLFA
What is the function of this protein?
The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase.  In addition, it is also involved in reducing some disulfides in a coupled system with glutathione reductase (By similarity).
What are the official names of this protein?
Glutaredoxin 1, Grx1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
Protein: MUTL_KLEP7
Sequence: MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGSGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASISSVARLTLTSRTAEQQEAWQAYAEGRDQAVTVKPAAHPVGTTLEVLDLFYNTPARRKFMRTEKTEFGHIDEVVRRIALARFDVTINLSHNGKVMRQYRAVAQDGQRERRLGTICGAAFLEHALAIEWQHGDLTLRGWVADPLHTTPALAEIQYCYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQLDAPLAEKDDPPAPRPMPENRIAAGGNQFARPAEAREPATRFSITPSREPAASSGKPGGASWPHAQPGYQKQQGALYRQLLDTPTSPKPALQPPAAAELAGHSQSFGRVLTIVGGDCALLEREGGLALLSLTVAERWLRQAQLTPGAEAVCAQPLLIPLRLKVTEGEKQALAAAQPALAQLGIDVHTDALHVTVRAVPLPLRQQNLQILIPELIGYLAQQNAFDVGNIAQWMARNLTSEQTSWNMAQAIALLADVERLCPQLVRTPPGGLLQPVDLHSAMNALKDE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: NU2C2_PIPCE
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSSALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLMSVVSIYYYLKIIKLLMTGRNQEITPHMRNYRRYPLRSNNSIELSMILCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LNT_PROMM
Sequence: MGNDRSLALVQGAVGGVLAGIGIAHGGLLWMAPALALLWSACRFPVAASLWGFVAVLLSHRWLLALHPLTWVGVPAPLSVPVAASIWLFCGAAAAVLVGLWAWLGTSIAHLATREAGIRAQLSHALLMASIWGLAEVLLAGSPLFWIGVGGSLLPGDRALAGLARWFGAGGLATLQLLIGWWLWRTALAWRRGVGWRRSLLVGLLCLLLAHGFGWSLLRSSDATAPISVAAWQPAIPTRSKFSEEQQRRLPEALQNALDRADDLDAAWLVAPEGLLPPDAVLLRPAPLPLLSGGFRWLRGQQRSALLVVDRGERQASAFIDKHRLVPLGEWLPALPGGVFRGLSAVGGLQPGAASRLLQWPGPTAAVAICYELSNGAALAQAVADGAQWLLAVANLDPYPLALQRQFIALAQLRSIETARDLLSVANTGPSALVLATGKQQQLLAPFTEGVGLADLHFHQGISGYTRWREAPLIGLMLFAVVGLGLSRVRSWLISLMLC
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DTD_PSEPW
Sequence: MKGLLQRVRGARVEVAGEIVGAIDQGLLVLVAVEPEDTREQADKLLHKLLNYRVFSDEQGKMNLSLKDVGGGLLLVSQFTLAADTRSGMRPSFSTAAPPALGAELFDYLLQQAQGQHADVASGRFGADMQVHLVNDGPVTFLLQI
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_ALKCK
Sequence: MRFLTAGESHGPQLTAIIEGVPAQLPLLAEDIDRELARRQGGYGRGRRMQIEKDRVQIVSGVRHGMTTGAPITFVVENKDWKNWTKIMGAEPISEEEAEKMRRKLTRPRPGHADLNGAIKYGHRDMRNVLERSSARETTVRVACGALAKVILKACGIEVAGHVREIGGIRAEETNYATIQELQKRSEESPVRCLDEDASKKMMAAIDKAKQDGDSIGGIVEVVVAGVPIGLGSHVHYDRKLDGKIAGAVMSINAFKGVEIGIGFEAARLPGSQVHDEITWSEEEGYKRKTNRLGGFEGGMTNGMPIVVKGVMKPIPTLYKPLQSVDIDSKEPFAAGVERSDSCAVPAASVVCENVVAWEVANALLDTFGSDQLPLIQAAVERHHAASKEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: QUEF_PSEPW
Sequence: MHPAAEHSPLGKSSEYIATYMPSLLFPIPRTAKWAELGVTAQTLPWHGVDYWNCFELSWLLPSGKPVVAIGEFAIPADSPNIIESKSFKLYLNSLNQTVFATIGELQACLEKDLSAAAGKPVSVQVRTLAEVEAQGVVALPGQCIDALDVTISNYEQPQPELLRCNPERVVEETLHSHLLKSNCPVTGQPDWGSVVVEYKGRALDHASLLTYLISFRQHADFHEQCVERIYLDLKNLLQPEHLTVYARYVRRGGLDINPYRSTGAISPENVRLVRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_ERWT9
Sequence: MIGRLRGIILEKQPPVVLIEASGVGYEVQMPMTCFYELPDIQHEAIIFTHFVVREDAQLLFGFNSKPERALFRELIKVNGVGPKLALAILSGMSAQQFVTAVEREEIAALVKLPGVGKKTAERLVVEMKDRFKGMHGDLFASDAPFALTSEMPKETANDAEGEAVAALTALGYKPQEASRMIVKVGKPDADCETLIREALRAAI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.