PharMolix/UniProtQA huggingface dataset:
Protein: MTND_CITK8
Sequence: MSALTIYSDKDASQPQWHSTDAAEIAQQLNAKGVRFERWVADRDLGQAPAPETVITAYQHAIDKLVAEKGYQSWDVISLRADNPQKEALRAKFLNEHTHGEDEVRFFVEGAGLFCLHIGDQVYQVLCEKNDLISVPAGTPHWFDMGSEPNFTAIRIFDNPEGWVAQFTGDAIADAYPRLL
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: Y1710_LACDA
Sequence: MNKDMWKLSPKNIAALGIGSAVFVIVGRFASIPSGLPNTNFELVYAFLAMIAMIYGPTVGFGVGFIGHVLLDLMMYGQTWWNWNFAAGFLGFFIGLYALRVNIDQGEFSAKEMVIFNVVQVVANAIVWFLLGSVGDMVLNSEPAAKVFAQAGLTTLMDGLTIAVLGTILLKLYAGSRVKKGSLHKD
What are the official names of this protein?
UPF0397 protein Ldb1710.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPEL_STRZT
Sequence: MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQIRTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTIALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPDQFYGLHVRPDLKVGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVNPIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGIAAAFDMEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDGVMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: IDE1_ARATH
Sequence: MAVEKSNTTVGGVEILKPRTDNREYRMIVLKNLLQVLLISDPDTDKCAASMSVSVGSFSDPQGLEGLAHFLEHMLFYASEKYPEEDSYSKYITEHGGSTNAYTASEETNYHFDVNADCFDEALDRFAQFFIKPLMSADATMREIKAVDSENQKNLLSDGWRIRQLQKHLSKEDHPYHKFSTGNMDTLHVRPQAKGVDTRSELIKFYEEHYSANIMHLVVYGKESLDKIQDLVERMFQEIQNTNKVVPRFPGQPCTADHLQILVKAIPIKQGHKLGVSWPVTPSIHHYDEAPSQYLGHLIGHEGEGSLFHALKTLGWATGLSAGEGEWTLDYSFFKVSIDLTDAGHEHMQEILGLLFNYIQLLQQTGVCQWIFDELSAICETKFHYQDKIPPMSYIVDIASNMQIYPTKDWLVGSSLPTKFNPAIVQKVVDELSPSNFRIFWESQKFEGQTDKAEPWYNTAYSLEKITSSTIQEWVQSAPDVHLHLPAPNVFIPTDLSLKDADDKETVPVLLRKTPFSRLWYKPDTMFSKPKAYVKMDFNCPLAVSSPDAAVLTDIFTRLLMDYLNEYAYYAQVAGLYYGVSLSDNGFELTLLGYNHKLRILLETVVGKIANFEVKPDRFAVIKETVTKEYQNYKFRQPYHQAMYYCSLILQDQTWPWTEELDVLSHLEAEDVAKFVPMLLSRTFIECYIAGNVENNEAESMVKHIEDVLFNDPKPICRPLFPSQHLTNRVVKLGEGMKYFYHQDGSNPSDENSALVHYIQVHRDDFSMNIKLQLFGLVAKQATFHQLRTVEQLGYITALAQRNDSGIYGVQFIIQSSVKGPGHIDSRVESLLKNFESKLYEMSNEDFKSNVTALIDMKLEKHKNLKEESRFYWREIQSGTLKFNRKEAEVSALKQLQKQELIDFFDEYIKVGAARKKSLSIRVYGSQHLKEMASDKDEVPSPSVEIEDIVGFRKSQPLHGSFRGCGQPKL
What is the function of this protein?
Peptidase that might be involved in pathogen or wound response.  Not required for peroxisome biogenesis, indole-3-butyric acid (IBA) metabolism, fatty acid beta-oxidation or degradation of glyoxylate cycle enzymes during seedling development.
What are the official names of this protein?
Insulin-degrading enzyme-like 1, peroxisomal, Insulysin-like 1, Peroxisomal M16 protease, Zinc-metallopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MURC_RICTY
Sequence: MLLLELKKTNQTLGTIHFIGIGGVGMSGIAEILHNLGYKVQGSDLVENYNTKRLESYGIKIFLGHAKQNIKNVSYVVISSAIHQNNPEIKEALERKIPIIRRAEMLAELMRLKCSVAVSGSHGKTTTTSLIACLFEAAGLYPTVINGGIINNKSTNAYLGSSNYLIAEADESDATFIHIPSTIAIITNIDPEHLDYYQDFEILIGAFRSFITNLPFYGFAVCCIDHKIVRKLVDDITERKIITYGIDAEDAHIIAFNINTDIASSTFDVKISLPNVLGTTIIEKITIPTPGRHNILNSLAAIAVGIELDFGIKAIKNGFNNFKGVKRRFTKVAEYNQAVIIDDYAHHPEEIKATLATAKNIANQQNGKVIAIFQPHRYSRIKYLFDDFMLCFADADILYITNIYAAGEKPIEGITGQSLVDKMTQNKYHDKANFLAELDDVVSVIIDHAASGDMIIMMGAGNISSFANELDRRLLSQEILASSQNTDFDTSSYDKVIR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UGO1_YEAST
Sequence: MNNNNVTEATSRAQIRPYYDPDSFNAGYSAVFKPDEGVVDPHGYTIASKLNVINSSPTTKRMANALFKSSPMKKLSNSVNDGLSLEGSNGEITGLNNFEWAELVNIQKWRKIFEQLLDMFFRKYFQLLIQQPFDVARLLIQVGEFKIFKTTVDTNKPQAPIILRDEEGDGAAREGEEDAYDEEEIDFFPIERKIAEANSTAPIMAEETDHSHHEPTDISLTIAPQSLHTIDVINALFDQEGIRGLWKANNTTFIYNFLSLSIDTWFTGLLSSFLGVPDPYFMEVINSPDISKSFILALGAGVFTSIILLPVDLIRTRLIVTSFKKKKNVKTDGKNMVTNTRSLRQLIRCWSWRKNGVSIPLDMWSLTILQSINNSFFNKLFDLVIYNQFHIEKYSQTVMYNTMKFFSKSLELFIKLPLENLLRRCQLNYLLNDQRLSFKVDSTELIVKPKKYNGIWDVIRNNSNTNRGQLWNGWKVGVISLICGYGLQMMNKVDINMEQEKF
What is the function of this protein?
Required for mitochondrial fusion as well as normal mitochondrial morphology by bridging the essential interaction between FZO1 and MGM1.  May coordinate fusion of inner and outer membranes during mitochondrial fusion.
What are the official names of this protein?
Mitochondrial fusion and transport protein UGO1.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type II membrane protein.
Protein: Y5129_ARATH
Sequence: MRMFSLQKMAMAFTLLFFACLCSFVSPDAQGDALFALRISLRALPNQLSDWNQNQVNPCTWSQVICDDKNFVTSLTLSDMNFSGTLSSRVGILENLKTLTLKGNGITGEIPEDFGNLTSLTSLDLEDNQLTGRIPSTIGNLKKLQFLTLSRNKLNGTIPESLTGLPNLLNLLLDSNSLSGQIPQSLFEIPKYNFTSNNLNCGGRQPHPCVSAVAHSGDSSKPKTGIIAGVVAGVTVVLFGILLFLFCKDRHKGYRRDVFVDVAGEVDRRIAFGQLKRFAWRELQLATDNFSEKNVLGQGGFGKVYKGVLPDNTKVAVKRLTDFESPGGDAAFQREVEMISVAVHRNLLRLIGFCTTQTERLLVYPFMQNLSLAHRLREIKAGDPVLDWETRKRIALGAARGFEYLHEHCNPKIIHRDVKAANVLLDEDFEAVVGDFGLAKLVDVRRTNVTTQVRGTMGHIAPEYLSTGKSSERTDVFGYGIMLLELVTGQRAIDFSRLEEEDDVLLLDHVKKLEREKRLGAIVDKNLDGEYIKEEVEMMIQVALLCTQGSPEDRPVMSEVVRMLEGEGLAERWEEWQNVEVTRRHEFERLQRRFDWGEDSMHNQDAIELSGGR
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At5g10290.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MNMG_LEPBJ
Sequence: MIESKNQSFFPNRFDCVVVGAGHAGSEAAYIASKGGAKTLLITMNLDTIGQMSCNPAIGGIAKGHMVREVDALGGIMGKVIDNTGIQFKMLNTSKGPSVWAPRAQAEKKEYQLKVKHTLEAEKNLSMRQDTVEELLIENDQVIGVKTGRGFEIYTNHVILTTGTFLSSLVHIGTYQNENGRMCEPTVKGLSKSLAKYNLKLGRLKTGTPPRIHKNSVDLSVLAIQDGDANPSPFSFSTEKITRRQIPCYITYTNVETHKLIHENLSLSPMYSGQIQSTGPRYCPSIEDKVVRFADRERHQVFLEPEGYETTEIYLNGVSTSLPEEVQWKLVRSLKGLENAEIVRPGYAIEYDYVDPTELKPTLETKKIKGLYHAGQINGTTGYEEAAAQGLVAAYSVLHSLKNLDPLLFKRSESYIGVLIDDLVYKGVEDPYRMFTSRAEHRLLLRQDNADQRLMKYGYELGLVDQESYDRMKDKYERVNSVREKIYQIPLKPSDEFQNLLDQKGITNYKFGMKLDSFLKRPEIKIEDVEFMLPEVSSWSESEKNILEMEIKYEGYIKRELETIQWKNKYLDLAIPEDINYESIAGLKKEAIQKLKTHKPMTLEKAGQISGVDPSDVDLLLYHIKGKRKQEAEAS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_METPE
Sequence: MVQRPRGTRDFLPDEMEARRMIEGRMREAVRRWGYREVATPIFEDLSLFTMRSGQGIIDEMYVFQDKGGRDLALRPELTAAVLRMYVNEARVLAKPLRWCYFADCFRYERPQKGRYRQFWQFGVELIGADTAAADAEVILVADNAIRSSGLDYDLKIGHLGLMKHLLADVGEEVRRKVMAYLDKKEFDGLKDYLETAGLAALTDPLTRLLAAETLDEAFAVTGPLPEEGRIREMAALLDATGVRYSYNFGIARGLDYYTGMVFEGFAKNLGAESQIVGGGAYRLAQVFGGDDAPSVGFAIGFDRVMVALGEVQTRKQKIVGVVSTAEGRPFAFRVANAFRTAGIRADLDLSDRGLGAQLARAAKEADFAVLIGEREVATGTVTLKNLATGTQTAVTIDLAVRTVIDGSR
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_MAGMM
Sequence: MSRIGKKPVVVPDGVDLKINGTVVTAKGKLGELTRQFHEAITFAQEGKEVNVAVSGTDKKSSSLWGLSRTLLDNMVVGVSQGFSKQLEIQGVGYRAAVKGRTLELSLGFSHPVNYELPNGLEATVEKNTLITVKGYDKEVLGQACAEIRSWRPPEPYKGKGVRYVGEFVLRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PRKRA_RAT
Sequence: MSHSRHRAEAPPLQREDSGTFSLGKMITAKPGKTPIQVLHEYGTKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIAKEQGFSITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK
What is the function of this protein?
Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis.  Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing.  Does not seem to be required for processing of pre-miRNA to miRNA by DICER1.  Promotes UBC9-p53/TP53 association, sumoylation and phosphorylation of p53/TP53 at 'Lys-386' at 'Ser-392' respectively and enhances its activity in a EIF2AK2/PKR-dependent manner (By similarity).
What are the official names of this protein?
Interferon-inducible double-stranded RNA-dependent protein kinase activator A, Protein activator of the interferon-induced protein kinase, Protein kinase, interferon-inducible double-stranded RNA-dependent activator.
What is the protein family that this protein belongs to?
Belongs to the PRKRA family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm.
Protein: EARP_PSEPK
Sequence: MKATWDIFCSVVDNYGDIGVTWRLARQLVAEHGLAVRLWVDDLNAFTPMCPGADATAAQQWQHGVDVRHWPAAWLPVAPADVVIGAFACQLPAAYVEAMRARPQPPLWLNLEYLSAEDWVEGCHGLPSPQPNGLRKVFFFPGFTDKTGGLLREGSLLARRDGFQQSAEARRAFLQGLGVDLVPGALLISLFAYENPQLGNWLDALATADQPCHLLVPQGRVVAGLSQWLGEGPLHVGDVRTRGALTVQVLPFVSQDDFDRLLWSCDFNAVRGEDSFVRAQWAGQPMLWHIYVQDENAHWEKLEAFLAHYRCGLSDDADAALLGLWRAWNMDFDMGQAWRAARQHWPELQQHARLWGARQAAQPDLATALVHFYRNSL
What is the function of this protein?
Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.
What are the official names of this protein?
Protein-arginine rhamnosyltransferase, EF-P arginine rhamnosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 104 family.
Protein: OTSA_ECO24
Sequence: MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSGETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPAWDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPTPEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKAFRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLAYEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLYYLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAANELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISDLKQIVPRSAESQQRDKVATFPKLA
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose.  Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Acts with retention of the anomeric configuration of the UDP-sugar donor.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: DNAJ_LEPBA
Sequence: MSDRGYYEVLGVSKGASDDEIKSAYRKLAIKYHPDKNKGDKEAEEKFKEATEAYEVLRDPQKRQAYDQFGKAGVNAGAGGGYGAGAYTDFSDIFGDFGDIFSEFFGGGGGGGSRGGGRRSGPQRGSDLRYNLEVSLEDAALGKEYKIEIPRLETCVDCTGSGASKGSSPTVCPDCSGTGQVRRTQGFFSVTTTCPRCKGKGKVISNPCKTCKGEGLTEKRRTIHIKIPAGVESGSRLKVSGEGESGPNGGPSGDLYVVTHIKKHPVFERQGNDLIVQKSISLSMACLGGEIEVPSIDGKTIQLKIPEGTESGQIFRLKGHGIPYLGSYGKGDQHVIIKVEIPKKLSKKQKELMEEFARESGEKVGSGGKSKLFFR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHS27_CAEEL
Sequence: MESKVVALNRESRRWKKSSFNELLKRARNQKSTICNRFTRKNTPNILVTFTSRLTLLRPTFFNFACWHSAMEIFESMSFSVKFDKELLPIGRHGLTAGWLIESLGQLLNSDNIRNIKCSQLGTDGFVSQIMRVVIEFTNNQTKKYIVKMPETTNIKAALEKTTQQKMPEGADEQFIGGLTMFFNREVEYYAMEKIPGLRTPKCYHAQQWDNGKTTGAIVMQDLEGMVSVPYYESLNLQQIASIGSQMLNLHLFSIGMSDEWRQKFPFPMELIDTVSNMTDIVKLYVSRNPELEEGFSKVEKMYQDRELFTKVLRDSHKSLGIDDFLCHGDLWFYNLMWIPRKSGSEVASNHLGSIIDWQNVHTGNICEDFCHMLTFCCDTEIRRQAENTFLPYYYNQLKAKAVEAGKKLNLTLNQFLRAYRRNFIAHALHLPFIVSIMLCVKPADDEIVQKIRNQMSGALWSAAQFAVTSYVCVRVLKFLYIMCKSVLVHFITPKHDLDYLKDTWTVITGGTDGIGKAYIEELCKTRGLKKFYLIGRNIDKLNNTKKELVEQHGCEVMCHVHDFEKDDLSALPKDLETLDVGILINCAGIAPHIIGTLTELPEGLASKILRVNLMSAVKMTEMILPNMVKKKRGIIVNISSMTGWRRFRTSVLTRLAKLHYPSSPTPCQMNTEELEFVFSVSFQCSLLPRSPRMKLKKRTISSLSPLKTLPNKLSELSGLIGKSQRAVCNMMFRLPLEHCSPFGFSKYFSSLLLCSEFISIVLPLIKRRTRERIIRVFIISRLSIFVHFYHDFFLLNAIFQIKKFSCELNFLESFF
What are the official names of this protein?
Uncharacterized oxidoreductase dhs-27, Short-chain dehydrogenase 27.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CHLL_SYNJB
Sequence: MEERAVKLAVYGKGGIGKSTTSCNISVALARRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLEAKGYHHEDIYPEDVIYRGYGGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFDEYDVILFDVLGDVVCGGFAAPLNYADYCLIVTDNGFDALFAANRIAASVREKAKTRKLRLAGLIGNRTSKRDLIDKYVSAVPMPVIEVLPLIEDIRVSRVKGKTLFEMAETDPSLEPVCQYYLNIADELLARPEGIVPQPAEDRELFALLSDFYNTPARQLALV
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: IHFA_BRUME
Sequence: MGGKTVTRADLAEAVYRKVGLSRTESAALVEMILDEVCDAIVNGETVKLSSFATFQVRDKNERIGRNPKTGEEVPILPRRVMTFKASNVLKQRILQEHQKRQGKTSK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ENGB_BURO0
Sequence: MAFLLHQARFYTTVNHLRDLPPTVQPEIAFAGRSNAGKSTAINVLCNQKRLAFASKTPGRTQHINYFSVGPAAEPVANLVDLPGYGYAEVPGAAKAHWEMLLSSYLATRSQLCGLILMMDSRRPLTDLDRRMIEWFAPTGKPIHTLLTKCDKLTRQESINALRNTQKGLDAYRDQGVKGKLTVQLFSALKRTGLDEAHELIESWLRPSVADEKSEPVAQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RLME_BRUA1
Sequence: MSKAGGNKGGSRTGGRGGAGSSNLHVRVKKKAGTIKESSRRWLERHLNDPYVHKSRQDGYRSRAAYKLIEINDRYNLLKKGQKIIDLGAAPGGWSQIAARIVGSTDENPQVVGIDYLHVDPLPGVILLEMDFLDDEAPQKLMDALGDKPDLVISDMAAPTTGHRRTDHLRTVHLCEVAADFAVSVLKPGGHFLTKTFQGGTENELLALLKQKFRSVHHVKPPASRAESVELYLLARDFKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_FRATO
Sequence: MNIENYLSETLAKVFQKLGYAESFAKVVTSTREDVGHFQCNGAMPLAKFAKKPPLAIAEEIVEHIDAEDIFAKLEVAKPGFINITLAPKFLADTTNRFLNSNKFGVQNNLPNRKVVLDFGGPNVAKPMHVGHIRSALLGDALQRIHRFCGDTVISDVHLGDWGTQMGMLIEEIKLQSPQLVYFDENYTGEYPTESPITVQELAEIYPRASKRCKSDINEMEKARLATFELQQGRRGYVALWQHFVRISIDAVKKDFDSLDVHFDLWLGESDANKFIDEMISYFQANNFIYEDEGAWVIDTNKDGVPPLIVIKKDGGVMYGTTDLATLWQRSKDLDPDEIIYVVDKRQSLHFKQVFSVAERTKVVSEKCKLKHVAFGTVNGKDGRPFKTREGGVMHLADLISQAKEYAKNRMPDENDDSIIDQIAMATIKFGDLINNYANDYFFDLEKFAQHEGKTGPYLLYTVVRAKSILRKIFGDNYDIKSLAKDYKVVNAHNEYEEKLQLQLIQFPIAVQRAYENSQPHHICEYAYSLANSFNKFYVNCPINNLDDESLKKARIALCMATVKAMTIASDLIGISIPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_BORA1
Sequence: MTRTDIERPVRTQAEEKARYEGNKLSKRLARETTRALSDYNMIEEGDRVMVCLSGGKDSYAMLDILMALQKRAPFRFELIAVNLDQKQPGFPADILPNYLSSLGVPFHIETQDTYSIVTRVLAEGKTMCSLCSRLRRGILYRVADELGATKIALGHHRDDILGTLFLNLFYGGKLKGMPPKLVSDDGRHTVIRPLAYIAETDLIAYAELKQFPIIPCNLCGSQENLKRKEVSRMVQEWDRKFPGRSWNVFNALSRVVPSHLMDRDLFDFVGLKPTGLPDANGDIAFDEPQTDDACDASAPTDGLNEQQIVFSRFS
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_ECO24
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PPIP1_MOUSE
Sequence: MMAQLQFRDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDVEELLRQRAQAEERYGKELVQIARKAGGQTEMNSLRTSFDSLKQQTENVGSAHIQLALALREELRSLEEFRERQKEQRKKYEAIMDRVQKSKLSLYKKTMESKKAYDQKCRDADDAEQAFERVSANGHQKQVEKSQNKAKQCKESATEAERVYRQNIEQLERARTEWEQEHRTTCEAFQLQEFDRLTILRNALWVHCNQLSMQCVKDDELYEEVRLTLEGCDVEGDINGFIQSKSTGREPPAPVPYQNYYDREVTPLIGSPSIQPSCGVIKRFSGLLHGSPKTTPSAPAASTETLTPTPERNELVYASIEVQATQGNLNSSAQDYRALYDYTAQNSDELDISAGDILAVILEGEDGWWTVERNGQRGFVPGSYLEKL
What is the function of this protein?
Involved in regulation of the actin cytoskeleton.  May regulate WAS actin-bundling activity.  Bridges the interaction between ABL1 and PTPN18 leading to ABL1 dephosphorylation.  May play a role as a scaffold protein between PTPN12 and WAS and allow PTPN12 to dephosphorylate WAS.  Has the potential to physically couple CD2 and CD2AP to WAS.  Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymerization required for synapse induction during T-cell activation.  Down-regulates CD2-stimulated adhesion through the coupling of PTPN12 to CD2.  Also has a role in innate immunity and the inflammatory response.  Recruited to inflammasomes by MEFV.  Induces formation of pyroptosomes, large supramolecular structures composed of oligomerized PYCARD dimers which form prior to inflammatory apoptosis.  Binding to MEFV allows MEFV to bind to PYCARD and facilitates pyroptosome formation.  Regulates endocytosis and cell migration in neutrophils.
What are the official names of this protein?
Proline-serine-threonine phosphatase-interacting protein 1, PEST phosphatase-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, lamellipodium. Cleavage furrow. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, uropodium. Note=Colocalized with PTPN12 in the cytoplasm and the perinuclear region (PubMed:11711533). During interphase, colocalizes with F-actin in the cortical cytoskeleton, lamellipodia, and stress fibers (PubMed:9265651). In dividing cells, colocalizes with the F-actin rich cytokinetic cleavage furrow (PubMed:9265651). Colocalized with CD2AP and WAS in the actin cytoskeleton within the cytoplasm (PubMed:12530983, PubMed:9488710). Colocalized with CD2, CD2AP and WAS at the site of T-cell:APC contact (PubMed:12530983). Mainly cytoplasmic in T cells. Colocalizes in cluster with CD2 near the cell surface membrane in activated T-cells. In monocytes, forms a branched filamentous network in the cytoplasm. In transfected cells, forms relatively straight filaments radiating out from the nucleus. Filament formation requires an intact tubulin cytoskeleton. In migrating neutrophils, colocalizes with PIP5K1C and DNM2 to the trailing edge of the uropod in a actin-dependent manner (By similarity).
Protein: RK19_PROWI
Sequence: MTNFKDIIKKIEYKFSKHQLPDIKVGDLIRLGISIQESGKQRVQPFEGTVIALHKAGLNTTITVRKILQGIGVERVFPIHASCLTSIQVLRRSQVSRAKLYYLRNRTGKATRLKEKFEKLPPIWVNKLP
What are the official names of this protein?
50S ribosomal protein L19, plastid.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
What are the subcellular locations of this protein?
Plastid.