PharMolix/UniProtQA huggingface dataset:
Protein: HSLO_SYNY3
Sequence: MADQLIRATAADGGIRAVGVITTNLTEEARQRHRLSYVATAALGRTMAAGLLLASSMKQEKSRVNIRIRGNGPLGGLLVDAGLDGTVRGYVQNPSVELAPNAQGKLDVGGAVGQDGFLYVVRDVGFGYPYSSTVELVSGEIGEDVTHYLVTSEQTPSALLLGVFVGKDGVTAAGGLLLQVMPKAARDEALVAALESRLGHLTGFTPLLRSGKSLKDIFQELLGDFGLAILPEVQLLRFDCRCSFPRVLGALKILGQDELEDMIEKDNGAEATCDFCGEVYQADRHHLAQLIGEIQREKAEKL
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP8_ARATH
Sequence: MNGTSPDESPDSTTQRIDSFNGEQRVYFVPLRWWKDAQDSMPSESVEKREILYTASCGSSYGGPMKLINNIFNSDILFDLRREGDALQNGETGEASVSGRDFALVSSDMWLQALKWYHDDKNTEKGVKSFSAGGVDRGDVYPVQLRLSVLQETNSLAVKICKKDNSVECFRRACKIFSLDSEQLRIWDISGQTTLFFESDVSNSKDCQQQADQEILLELQIYGLSDSIKLKESKKEDGSTQQTNGITNGMNGGTVFRFGRSNSLSFLGKAGEAGTLGLTGLQNLGNTCFMNSSLQCLAHTPKLVDFFLGEYSKEINLDNPLGMKGEIALAFGDLLRSLWAPGASTVAPRTFKAKLARFAPQFSGFNQHDSQELLAFLLDGLHEDLNRVKNKPYVEAKDGDGRPDAEVADEYWRNHVARNDSIIVDVCQGQYKSTLVCPICKKVSVMFDPFMYLSLPLPCTSMRTMDLTVMSADGSSLPIPLTVNVPKFGKFEDLHKALVTACSLPEEETLLVTEVYNNRIIRFLEEPTDSLTLIRDGDKLVVYRLKKDANNSPLIVYMHQKLEEQFISGKSSPTWKAFGIPLVSRLCDVENGSDVENLYLKLLSSFKMPTEFFTENLENPTEEEATDKTDTDGTTSVEDTNSTDVKETTESLPDPVLRLYLTDDRGNSIEAEMLKEKPVNKSKRLNVLARWPVKELDVYDTCLLSSLPEVSKSGTKRPQESVSLFKCLEAFLTEEPLGPDDMWYCPGCKEHRQAIKKLDLWRLPEILVIHLKRFSYSRFMKNKLEAYVDFPLDNLDLSSYISYKNGQTTYRYMLYAISNHYGSMGGGHYTAYVHHGGDRWYDFDDSHVHQISQEKIKTSAAYVLFYKRLVD
What is the function of this protein?
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 8, Deubiquitinating enzyme 8, AtUBP8, Ubiquitin thioesterase 8, Ubiquitin-specific-processing protease 8.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: TR130_ORYSJ
Sequence: MANYLAQFQTIKSSCDRIVVAVEDVSDLWLNVKESFEQRLPVKKACLNNKARNPVFVENLPAEFIQTTDSRLRSRFPQDQYLFWFREPYATVVLVSCEDLDEFKTILKPRLKLIVQNDEREWFIVFVSKAHPSNDQASKMAKRVYARLESDFNTKKRERCCKFDLHGPDAEFWDDFDSKMVDCIRNTLDRRVQFYEEEIRRLSEQRFTPIWNFCNFFILKESLAFMFEMTNLHEDSLREYDELELCYSESVNSPGKHREFGGLDTGDDQAALLNPGFKALTQIVQDDVFREFEFRQYIFACQAKLLFKLHRPIEVAARGYAFVVSFSKTLALQENGLPFCFREVWVITACMDLIKATTSHYDGTAVAIDSEREFCRIQGDLYSLCRIKFLRLAYLIGYGVEIEKSPVNSASLSMLPWPKPATWPSIPPDSSAETMAKEKMILQAKSREKIFNIHRKPLPLEPSLLLREANRRRAFLSVGNISELYDSGDGSGLDANSKPSPNKSASNYMARTMSGPATSETSLPVDRPMRLSEIHVAAEHALKQTVSDPNFMTSLSSLEEFEKRYMELTKGAADNYHHSWWKRHGVVLDGEIAALFFKHENYDLAAKSYEKVCALYSAEGWEELLADVLPDLAECQKILNDEAGYLTSCVKLLSLESGLFSSKERQAFQSEVVRLAHSEMKHPVPLDVSSLITFAGNPAPPLELCDGDPGTLSVAVWSAFPDDITLESLSLRLSASSSADEGLKAIKSSDARVLVPGRNIITFDIPPQKPGSYVLGALTGQIGKLSFRSHGFSQDGPVDTDEFMSFEKPTRPVLKVRKPRALVDITPAVSSALLMNELQWIGLIVKPIDYSLKDGILHIDAGAGLKIEESQMIEIETYGSDVEHVGGTDASKTSSSSTDTRKVEKVPIEDGKIKIPDWASDVTTLVWFPVRAIDDTIARGASPASPQKQSIVDGMRMIALKLEFGVFLNQVFERTIAVHFTNPFHVSTRVVDKCYDGTLLLQVILHSEVKATLHVKDIWLDLQSGFEHTGKGDGRPTSNLFPLVIAPSSRAGILFVIRLSALGDMDELEKADSMLNIKYGISGDRTTGAHSPVPVKPDDSEELVFKIAVKMKRPVLDPCVAVGFLPFSSDCLRVGQLVNMRWRVERLKNPEDASLLADEILYQVDANPQNWMVAGRKCGHVSLSNKQGSRIEITVTCVPLVSGYVHPPQLGLPHVGEANISCNPAGPHLVCVLPPTLSTSYCIPA
What is the function of this protein?
Specific subunit of the TRAPP II complex, a highly conserved vesicle tethering complex that is required for the proper transport of proteins in post-Golgi trafficking pathways to the growing cell plate in mitotic active cells.
What are the official names of this protein?
Trafficking protein particle complex II-specific subunit 130 homolog, TRAPP II-specific subunit 130 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM1 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Early endosome.
Protein: KGUA_XANCP
Sequence: MRGTLYIVAAPSGAGKSSIVNATLARDPKIALSISFTSRAPRPGERHAEHYHFVSAEEFQGMIEAGDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFILPPSRQALDERMRKRGQDSEDVMAQRLAAAREEMLHFEEFDYVIINETFDTAVSEMCAIFTASRLRRQAQQQRHAGLIQALLD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_DESVV
Sequence: MDIMKKIELEHLRMDLPKFRSGDTVKVHLRIVEGEKERIQMFQGNVIRIHRGTTGGTFTVRKVSDGVGVERVFPLHSPFIDRVELITEGRVRRSRLYYLRDLRGKAARIKPKNRF
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: JAC1_YEAST
Sequence: MLKYLVQRRFTSTFYELFPKTFPKKLPIWTIDQSRLRKEYRQLQAQHHPDMAQQGSEQSSTLNQAYHTLKDPLRRSQYMLKLLRNIDLTQEQTSNEVTTSDPQLLLKVLDIHDELSQMDDEAGVKLLEKQNKERIQDIEAQLGQCYNDKDYAAAVKLTVELKYWYNLAKAFKDWAPGKQLEMNH
What is the function of this protein?
Co-chaperone required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria.  Stimulates the ATPase activity of its specialized Hsp70 chaperone partner SSQ1, to mediate the transfer of iron-sulfur clusters from ISU1 to GRX5.  Binds to the substrate protein ISU1 and targets it to SSQ1.
What are the official names of this protein?
J-type co-chaperone JAC1, mitochondrial, J-type accessory chaperone 1.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: H2A2_SCHPO
Sequence: MSGGKSGGKAAVAKSAQSRSAKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVVPNINAHLLPKQSGKGKPSQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A-beta, H2A.2.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HFLD_SHESR
Sequence: MNEQLHNRTMAFAGILQAIAQVQHLARHGESDTDELAASLNTILVTNPESAADVYQDKAALHKGYKLVLNQLGDSSQKDVEITRYLVGILALERKLTRSNSGLAMLAERINQVNRQLHHFAITDEQVIANLASIYSDIISNLGPKIQISGNPLCLQRPIVQHKIRALLLAAMRSAVLWRQLGGKRRHLVFARKAIIDTAKKSLTL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYB6_CYACA
Sequence: MSKFYDWFQERLEIQLIADDISAKYVPPHVNVFYCFGGMTLTCFLVQLATGFAMTFYYKPTTIEAFSSIQHIMTQVSFGWLIRSLHRWSASMMVLMMILHIFRVYLTGGFKKPRELTWITGVILAVLTVSFGVTGYSLPWDQVGYWACKIVTGVPEAIPVVGDNVVEILRGGTGVGQATLTRFYSLHTLFLPALSVIFLLAHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RHAA_BACSU
Sequence: MTIKANYDSAKQAYEKWGIDVEEALRQLEQVPISIHCWQGDDIEGFEVNKGELSGGIDVTGNYPGKAQTPEELRRDLEKALSLIPGKHRVNLHAIYAETNREAVERDELKPQHFENWVKWAKNLGLGLDFNPTLFSHEKAADGLTLSHPDPDIREFWIRHCIACRRIGEYFGKELGTPCLTNIWIPDGYKDIPSDRLTPRKRLKESLDRIFSEEISEQHNLDSIESKLFGLGSESYVVGSHEFYLAYALTNHKLCLLDTGHFHPTETVSNKISSMLLYTDKLALHVSRPVRWDSDHVVVLDDELREIALEIVRNHALEKVAIGLDFFDASINRVAAWTIGTRNMIKALLYALLLPNGYLKQLQEEGRYTERLALMEEFKTYPFGAIWDSYCEQMGVPVKEAWLYDIKEYEQQVLLKRKASSPIV
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_MYCLE
Sequence: MAVKIKLTRLGKIRNPQYRVIVADARTRRDGRSIEVIGRYHPKEEPSLIDINSERTQYWLSVGAKPTEPVLKLLKITGDWQKFKGLPGAEGRLKVAPPKPSKLELFNAALAVADGGPTTEATRPKKKVSAKKAAKAVESDAEGAKATKAYALAEGDEQSE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TAL_HYDS0
Sequence: MQFFIDTANIDEIKQAIDWGILDGVTTNPTLAAKTGRPFMDVVKDILSIVDGPVSLETVSLDTEGMVKEGRFLAELGDNVVVKIPMTKEGMKAVNILEEEGIPTNVTLIFSPMQALIAAKAGASYVSPFIGRLDDISTDGMNLVRDIRTIFDNYGYETEIIAASIRHPIHVLEAAKAGADIATIPFNVLEALFRHPLTDIGIDKFLKDWEKVPNKPF
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAB_LEIDO
Sequence: MYADATHPRRACWCGAGGVSGCVRQRHAYRCSRLLAGVLLIVGALTLTLAVSTVPAAWAAGAVASSDEPVYLLNAMYSLSDYNAKHAKALWLGIDSALHAVGYTAARGRPIKIIEPDPTDDLSDIVAVVLKALKDYPTLLGVIGPYSDTRLGAVLISPEIQNSGLMFLGPFTGSSSMRAWNENLYFMRAEPRLEIMAMVKHIANTFRARRTAFMYLTGEQYGSFEHKSLVELMTSLSLDPPAVYSASYSTSTAVNMTAFDAMADTRPQVIIIWGIPAGQVEELLKVVLTDPRTSSAYIMPSFALQQMTFQVYYDLAMAGKLTPVDGQIISSATSFPLTEPASVHLRVFRAQMGEYMVKTGRVDASLWADEAKAVQQYGPWEHEASSSDSAAYVNNFFNEHPCVTQLMIAGWISGSLIAQTLAEENRIANRTAYRQYMFSQQRYIVGEDFVLGDYGGPCNGVAEFLGAVCYCNQGGHSAVLSRLDRAVWTVITESGVSFTQKNCYSDGTTLPRPLNFLTLIFAEHPLLAQVGLTFKTSISTLVAYLQYNASPVNAATVNVTDTTPQALHDAVTTNYTTDVVVGVTVKGMNVDGYLVPSPIHPRPHLVELLRNYVYLMPTLEQQMFVLYAKLSAVRGVTSIDSAVHMILHGYASDEVANITAVLRKSAATFNYDNPTVTAVPSTKTVGSALAHGQINFVLAVTAADVADIVDFLVEEKTSIVVIVFDDLVIQYPTLVTALKSKPASVQARVITFTNLPLWSDTSESAHAASKLLTVFHDALPDPSQHTPGFLSAVLTGSFCASMRRLADSVHSTSLTDMVYREGSVTTFAEPFGRFQWGCTTTPTDRFCVYHNYGAQGIVMLSVQRMLDPTVPQLSSPMTPTMDYRPRQRSHALTPAQRGGAIAGIALLTVILLAVAGLALYCCMDNRNNDAAPKDGDEPVTLLFTDIESSTALWAALPQLMSDAIAAHHRVIRQLVKKYGCYEVKTIGDSFMIACRSAHSAVSLACEIQTKLLKHDWGTEALDRAYREFELARVDTLDDYEPPTARLSEEEYAALWCGLRVRVGIHTGLTDIRYDEVTRGYDYYGDTSNMAARTEAVANGGQVVATEAAWWALSNDERAGIAHTAMGPQGLRGVPFAVEMFQLNAVPGRRHAALRTEIEAILPDDTATDTASSAAGALLSSVGTINGPAAGIAFVLASCFAPYPVAQRVRELQPLLSKWGVGAPPRSRLVSEEDYCQGLMNRLAIRIATVSQARCPVGNNGAAVDLDVQHAGTAEVMNPLLGEGSFISDGARARHSGLTAVPPSAEPSAMRMRRVGRKVPERPTVCNVRGAH
What is the function of this protein?
Could act as a receptor for an unknown ligand.
What are the official names of this protein?
Receptor-type adenylate cyclase B, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FA9_SHEEP
Sequence: RASVLHTSKKLTRAETIFSNMNYENSSEAEIIWDNVTQSNQSFDDFNRVVGGEDAARGQFPWQVLLHGEIAAFCGGSIVNEKWVVTAAHCIKPGVKITVVAGEHNTEKPEPTEQKRNVIRAIPYHGYNASINKYSHDIALLELDEPLELNSYVTPICIADREYTNIFLKFGYGYVSGWGRVFNRGRSASILQYLKVPLVDRATCLRSTKFTIYNHMFCAGYHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYEV
What is the function of this protein?
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
What are the official names of this protein?
Coagulation factor IX, Christmas factor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYY_DESOH
Sequence: MSVVDILSERGFVEAFTHEQELRDLAAESAVTCYIGFDPTASSLHVGSLVPIMALAHMQRNGHRPIALVGGGTGLVGDPSGKTEMRQLITPETVEANIEGIQRQLSRFIDFDGGKALLVNNADWLTGLEYIPFLRDIGRHFSVNRMIKAESYRMRLESEEGLSFIEFNYMLLQAYDFLKLCGDRDCVLQMGGSDQWGNIVAGIDLVRRVLNRQVYGLTFPLITTSSGAKMGKTAAGAVWLDAERTSPYDYYQYWINTDDQDVARFLSLFTFLPMPEIQEVKRISGADLNSAKAVLAFEATRIAHGTDAAVQAHSDAAVNFGRRDIPQDLLPSSTIPRDAEGTGAAVSGTAPQTEMTMAELSEGIPAFVLFHTVGLADSKGQARRLIQQGGGYVNDRRIESDEYRVSAEDLDDAKIVLRAGKKRYHTIVVRKGA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSP_COLLI
Sequence: MDPTNSPQEPPHTSTPGPFDGPQWPHQAPRGMYLSVAVLMGIVVISASVVNGLVIVVSIRYKKLRSPLNYILVNLAMADLLVTLCGSSVSFSNNINGFFVFGKRLCELEGFMVSLTGIVGLWSLAILALERYVVVCRPLGDFRFQHRHAVTGCAFTWVWSLLWTTPPLLGWSSYVPEGLRTSCGPNWYTGGSNNNSYILTLFVTCFVMPLSLILFSYANLLMTLRAAAAQQQESDTTQQAERQVTRMVVAMVMAFLICWLPYTTFALVVATNKDIAIQPALASLPSYFSKTATVYNPIIYVFMNKQFQSCLLKMLCCGHHPRGTGRTAPAAPASPTDGLRNKVTPSHPV
What is the function of this protein?
Produces a slow and prolonged phototransduction response consistent with the non-visual function of pineal photoreception.
What are the official names of this protein?
Pinopsin, Pineal gland-specific opsin, P-opsin, Pineal opsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPOE_STAA2
Sequence: MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: CRIM1_HUMAN
Sequence: MYLVAGDRGLAGCGHLLVSLLGLLLLLARSGTRALVCLPCDESKCEEPRNCPGSIVQGVCGCCYTCASQRNESCGGTFGIYGTCDRGLRCVIRPPLNGDSLTEYEAGVCEDENWTDDQLLGFKPCNENLIAGCNIINGKCECNTIRTCSNPFEFPSQDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCVCNPAGCLRKVCQPGNLNILVSKASGKPGECCDLYECKPVFGVDCRTVECPPVQQTACPPDSYETQVRLTADGCCTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNDTKPACVFNNVEYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCERYYVPEGECCPVCEDPVYPFNNPAGCYANGLILAHGDRWREDDCTFCQCVNGERHCVATVCGQTCTNPVKVPGECCPVCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNGCRTCQCINTEELCSERKQGCTLNCPFGFLTDAQNCEICECRPRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWHDGCRECYCLNGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDSVISCFSESCPSVSCERPVLRKGQCCPYCIEDTIPKKVVCHFSGKAYADEERWDLDSCTHCYCLQGQTLCSTVSCPPLPCVEPINVEGSCCPMCPEMYVPEPTNIPIEKTNHRGEVDLEVPLWPTPSENDIVHLPRDMGHLQVDYRDNRLHPSEDSSLDSIASVVVPIIICLSIIIAFLFINQKKQWIPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQVDSSQRMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV
What is the function of this protein?
May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival.  May play a role in capillary formation and maintenance during angiogenesis.  Modulates BMP activity by affecting its processing and delivery to the cell surface.
What are the official names of this protein?
Cysteine-rich motor neuron 1 protein, CRIM-1, Cysteine-rich repeat-containing protein S52.
What are the subcellular locations of this protein?
[Processed cysteine-rich motor neuron 1 protein]: Secreted. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: ERA_STAS1
Sequence: MTEHKSGFISIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTQEDAQIIFLDTPGIHKPKHKLGDYMMRVATNTLSEIDAIMFMVNVNEDIGRGDEYIMEMLKTIKTPVFLVLNKIDLVHPDELMPRIEKYKKYMDFTEIVPISALEGLNVDHFINVIKSYLPEGPKYYPDDQISDHPEQFVVGELIREKILHLTSEEIPHAIGVNVDRMIKEDEDRVRIEATIYVERDSQKGIVIGKGGKKLKEVGKRARQDIERLLGSKVYLELWVKVQKDWRNKVNFIRQMGYLEDRD
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: RS21_BACLD
Sequence: MSKTVVRKNESLEDALRRFKRSVSKTGTLQEARKREFYEKPSVRRKKKSEAARKRKY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: VP5_BTV13
Sequence: MGKIIKSLSRFGKKVGNALTSNTAKKIYNTIGKAAERFAESEIGSAAIDGLVQGSVHSIITGESYGESVKQAVLLNVLGAGDEIPDPLSPGERGIQTKIKEIEEEQRNELVRIKYGKEIREKFGEQLEEIYQFMNGEVKGEEEQEEQYKVLCKAVDSYENLLVTENEQMRTLARALQREATERTENESKMVKEYRQKIDALKVAIEVERDGMQEEAIQEIAGMTADVLEAASEEVPLVGSGMATAIATGRAIEGAYKLKKVINALSGIDLSHLRTPKIEPTMVATTLEHRFKEIPDKELAVSVLAKNDAIVANTKEIKHIKEEILPKFKKIMEEEKELEGIDDKKIHPRVMMRFKVPRSQQPQIHIYSAPWDSDDVFFFHCVSHFHANESFFLGFDLGIDVVHFEDLAAHWHALGAAQEAKGRTLNEAYREFLNLSIGSAFTSPMHARRMIRSKTVHPIYLGSMHYDITYETLKTNATEARYDEDLQMHILRGPLHFQRRAILGALKFGVKVLGDKVDVPLFLKNA
What is the function of this protein?
VP5 protein is one of the two proteins (with VP2) which constitute the virus particle outer capsid.  Acts as a membrane permeabilization protein that mediates release of viral particles from endosomal compartments into the cytoplasm.  Permeabilization activity is probably negatively regulated by VP2 and is triggered by endosomal degradation of VP2 and exposure to low pH (By similarity).
What are the official names of this protein?
Outer capsid protein VP5.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP5 family.
What are the subcellular locations of this protein?
Virion.
Protein: PRIB_SHEPA
Sequence: MTTNNLVLAGTITRSRQFDSPAGIAHTVVMLEHKSQRYEAGMLRNVYCQIQVVLSGERFNGVAKNLTAGVEIQVEGFINLQQSRNGQNRLVLHAENVELKT
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: MLTF_PSEAE
Sequence: MFALTAYRLRCAAWLLATGIFLLLAGCSEAKAPTALERVQKEGVLRVITRNSPATYFQDRNGETGFEYELAKRFAERLGVELKIETADNLDDLYAQLSREGGPALAAAGLTPGREDDASVRYSHTYLDVTPQIIYRNGQQRPTRPEDLVGKRIMVLKGSSHAEQLAELKKQYPELKYEESDAVEVVDLLRMVDVGDIDLTLVDSNELAMNQVYFPNVRVAFDFGEARGLAWALPGGDDDSLMNEVNAFLDQAKKEGLLQRLKDRYYGHVDVLGYVGAYTFAQHLQQRLPRYESHFKQSGKQLDTDWRLLAAIGYQESLWQPGATSKTGVRGLMMLTNRTAQAMGVSNRLDPKQSIQGGSKYFVQIRSELPESIKEPDRSWFALAAYNIGGAHLEDARKMAEKEGLNPNKWLDVKKMLPRLAQKQWYAKTRYGYARGGETVHFVQNVRRYYDILTWVTQPQMEGSQIAESGLHLPGVNKTRPEEDSGDEKL
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: ATPG_VIBC3
Sequence: MAGAKEIRTKIGSVKSTQKITKAMEMVAASKMRRSQDAMESSRPYAQTIRKVIGHVANASLEYRHPYLEEREAKRVGYIIISTDRGLCGGLNINLFKKAITDMQTWKEKGAQIELAIIGSKATAFFNNSGAKVAAQVSGLGDSPSLEDLIGSVGVMLKKYDKGELDRLYLVFNQFVNTMVQKPKIDQLLPLPKSDSEDMQRDHMWDYIYEPEPKPLLDALLLRFIESQVYQGVVENLACEQAARMVAMKAATDNASNLIDDLQLVYNKARQAAITQELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KDPA_ECOLU
Sequence: MTAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERVLFRLPGVSDSEMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMH_STRU0
Sequence: MTKEFHHITVLLHETVDMLDIKPDGIYVDATLGGAGHSSYLLSKLNDNGHLYCFDQDQKAIDNAQVFLKSYVDRGMVTFIKANFRHLKSELNALGVTEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDSDAALTAYHVVNDYPFQDLVRIFFKYGEDKFSKQIARKIEQARAIKPIETTAELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQEAMTMLALNGRISVITFHSLEDRLTKQLFKEASTVDVPKGIPFIPEDMQPKFELVTRKPILPSQEELLANNRAHSAKLRVARKVRM
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.