PharMolix/UniProtQA huggingface dataset:
Protein: NU3C_GOSBA
Sequence: MFLLYEYDIFWAFLIISSAIPILAFLISGVLAPIRKGPEKLSSYESGIEPMGDAWLQFRIRYYMFALVFVVLDVETVFLYPWAMSFDVLGVPVFIEAFIFVLILIVGSVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HIS4_METPE
Sequence: MKVFPAVDILGGRCVQLVQGRRESATDFGDPLSCATQWLEEGATALHVINLDGAFGKAQANAALIRDLVDVTGVEVQLGGGIRSIADATAWLETGVDRIIIGTLATEHPEVLGTLASEYGGARIMAGVDARDGQIAVEGWQQTRGNFCTWATRFEEQGAGSLLYTNVDIEGLQQGVRLDPVKELIRMVSIPVVVAGGVSSPADLQGLHQAGVAGAVLGSALYSGKITLEEALKAIQ
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_STACT
Sequence: MKAIILAGGQSERFGAPKAFAEIDGKMFYEQIITVLDSMNMFNEIIISSNETLASEFKGARVIVDDSEHKNKGPLSGIYSVMKQDFESELFFVISVDTPLITAKAISQLYQFMVEHVIEDQLDIAGFKEGNHPIPTIAFYSPNCLPIIARALESDDYSMRHVYQQTASDWIDVSSVDDDTEWYKNINYPQDLESIKK
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMP14_PONAB
Sequence: MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLRVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADVMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVGNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPEDDRRGIQQLYGSESGFPTKMPPQPRTTSRPSVPDKPKNPTYGPNTCDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFDNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
What is the function of this protein?
Endopeptidase that degrades various components of the extracellular matrix, such as collagen.  Activates progelatinase A.  Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development.  May be involved in actin cytoskeleton reorganization by cleaving PTK7.  Acts as a positive regulator of cell growth and migration via activation of MMP15 in association with pro-MMP2.  Involved in the formation of the fibrovascular tissues in association with pro-MMP2.  Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis.
What are the official names of this protein?
Matrix metalloproteinase-14, MMP-14.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Melanosome. Cytoplasm. Note=Forms a complex with BST2 and localizes to the cytoplasm.
Protein: HYPA_XANP2
Sequence: MHEMAVCESLLSAMEEAAKAQNFSRVTRVRLAIGRFAGIEVEALRFGFDVVMRGSLAEGAELVVLEEDGSAWCFDCCETVALSHRLASCPKCGGERLVPNGGTDMKIKDLEVL
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: PRK1_CANAL
Sequence: MPQPPPNAYKAGTRLTVGSHKVSIIKYISEGGFAHVYTCTIDPPFQGSTVACLKRVVVPSKWQLSLLRQEVDAMRRLRGNKHIVSYIDSHASRLGDSNTSGTNHSQQQQYEVFLLMEYCENNGLIDFMNTRLVNKLTEKEIIDIMYQVTIGVAMCHHLRPPLIHRDIKIENVLIDGKGVFKLCDFGSSVNYLPPPRNPQELQLMKDDLMQHTTPQYRAPEMIDLSKGFPIDDKSDIWALGIFLYKLCYYTTPFERPNQSSLQELEHTILNCSETLRFSDQPGSIFSPRLKNAIKVCLRADPRRRPNAVQLLGEIAAMKGEKTIPNVVPYSVIEQQRTKQASALEEDTKKGQASFVETKKITSKPKTDPFANIDKSKFLNKSGYKLSSVTAESRTVPARPLSAFFDDGNTPRIYSQGNRSTPSVQDYVKEELAKGESYEFNEPDGTLEFLKSREEEKLNQRNDTGGSFKAAFKNGLRKISTGGNISANNTGSSVKSNRRASLKRIITGGSNHNRKHSEENTKNVEDSNPVSSAPKKLSIQHRMQQLLNQNDHQRVQKSAQGYGKYTDIKASEDIDEINKPTLSKHSQKKLSPPAVPVNLSSQRNKSQQSSSTTKKYPIKDSKPLSKVRNNPPKDSVKTKPPPPKPKKPVYLKSPTKLEIADQRRLSDASEISMPDLDDLEKQFSKRFPSYV
What is the function of this protein?
Protein kinase involved in regulation of actin cytoskeleton organization and endocytosis.  Phosphorylates the endocytic protein SLA1.  The CDC28-CLN3 complex phosphorylation of SLA1 enhances its further phosphorylation by PRK1, weakening SLA1 association with PAN1, an activator of the actin-nucleating ARP2/3 complex.  Plays a role in cell wall regulation and required for oxidative stress survival.
What are the official names of this protein?
Actin-regulating kinase PRK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Localized to sites of endocytosis.
Protein: RS8E_HALWD
Sequence: MKDQGRSTRKRTGGRLHDVSKKKRHQLGREPAETTVDDPRFQVIDARGSDDKLRALSTNIAQVADSGEVTTEEIENVVDNPANVNYIRRNIITKGAIIETSAGQARVTSRPGQTGQVSAVLLEDS
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: UEHA_RUEPO
Sequence: MAQSITFTFGAVAAAGIALAAGTAAQADTWRYAFEEAMTDVQGVYAQKFKEEIEANSDHEIQLFPYGTLGESADIMEQTQDGILQFVDQSPGFTGSLIPEAQVFFVPYLLPTDQDHLARFFKESKAINDMFKPLYADQGLELLNMFPEGEVAMTTKTPVTTCSDLDEVKFRVMTNPLLVESYKAFGATPTPLPWGEVYGGLQTNVIQGQENPTFFLYSTKIYEVTDYITYAGHNNFTTAVMANKDFYDGLSAEDQQLVQNAALAAYDHTVVYQQQAADTELAKIMEAKPEMQVTVLTDEQRSCFKEAAAEVEAKFIEMTGDSGAAILKQMKADLAATAN
What is the function of this protein?
Part of the tripartite ATP-independent periplasmic (TRAP) transport system UehABC, which imports both ectoine and 5-hydroxyectoine as nutrients, and not as osmoprotectants.  UehA binds both ectoine and 5-hydroxyectoine with high specificity and affinity.
What are the official names of this protein?
Ectoine/5-hydroxyectoine-binding periplasmic protein UehA, Uptake of ectoine and hydroxyectoine protein A.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUOH_BURP1
Sequence: MSLFDTINSGGAQLLGVAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPAGLLQPIADVLKLLLKEVIRPTAASRWLYLVAPVMTVVPAFAVWAVIPFQAGAVLANINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMTAGSLNLSEIVGSQQHGFFAGHGVNFLSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGESEIVAGHMIDYSGMAFALFFLAEYINMIVISALAATLFLGGWDAPFEFLSFIPGIFWLVLKIFALLSVFIWARATFPRYRYDQIMRLGWKVFLPVCVFWVIVVGFWMMSPLNIWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAK_METBF
Sequence: MAKILGIDLGTTNSCMAVMEGGEAVVIPNAEGARTTPSVVGFSKKGEKLVGQVAKRQAISNPENTVYSIKRHMGDANYTVTLQGTQYKPQEISAMILQKLKTDAEAYLGETIKQAVITVPAYFNDAQRQATKDAGAIAGLDVLRIINEPTSASLAYGLDKGDIEQKILVYDLGGGTFDVSILELGGGVFEVKSTSGDTRLGGDDFDQRIVNYLLAEFRKIEGIDLSKDKAVLQRLTDAAEKAKIELSGVASTNINLPFLTVGADGEPKHLDIDLTRAQFQKMTEDLLEKTLVSMRQALSDAKLTPNDLDKVILVGGATRMPAVVELVENFTGKKPYKNINPDEAVAIGAAIQAGVLGGEVKDVLLLDVTPLTLGIETLGGIATPLIPRNTTIPTKKSQVFSTAADNQPSVEIHVLQGERGVASENKTLGRFTLDGIPPAPRGIPQIEVTFDIDANGILHVGAKDLGTGKEQSISIQKPGGLSDDEIDRMVKDAELHAEEDKKRKEDVETRNNAEALINAAEKTLKEAGDAATEDQKSKVTAAIDDLKKALEGKDSEDIKSKTEALQEAVYPISTAMYQKAQQQAQQAQQAEGEAGSHDAQGPDETVVDADYEVVDDEKRK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: FCRL3_HUMAN
Sequence: MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKVALICSSISHSLAQGDTYWYHDEKLLKIKHDKIQITEPGNYQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNVILRCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRDNSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRASSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTLGLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSLRSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQGSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESDAGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPRAHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAPSGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRVTVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILYWFYHEDDTLGNISAHSGGGASFNLSLTTEHSGNYSCEADNGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILVLAAAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSSRPSRIDPQEPTHSKPLAPMELEPMYSNVNPGDSNPIYSQIWSIQHTKENSANCPMMHQEHEELTVLYSELKKTHPDDSAGEASSRGRAHEEDDEENYENVPRVLLASDH
What is the function of this protein?
Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation.  Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells (PubMed:23857366).  Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases.  Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling (PubMed:19843936).  Regulatory T-cells expressing FCRL3 exhibit a memory phenotype, are relatively nonresponsive to antigenic stimulation in presence of IL2 and have reduced capacity to suppress the proliferation of effector T-cells (PubMed:20190142, PubMed:19494275).  Acts as a human-specific epitope on the cell surface of oocytes (oolemma) and plays a role during sperm-egg adhesion and fusion (PubMed:36070373).  Interacts with the IZUMO1-IZUMO1R/JUNO sperm-egg complex and replaces IZUMO1R/JUNO as IZUMO1 receptor during fertilization, thereby permitting species-specific gamete fusion (PubMed:36070373).
What are the official names of this protein?
Fc receptor-like protein 3, FcR-like protein 3, FcRL3, Fc receptor homolog 3, FcRH3, IFGP family protein 3, hIFGP3, Immune receptor translocation-associated protein 3, MAIA, SH2 domain-containing phosphatase anchor protein 2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TRUB_STAAN
Sequence: MYNGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAGVLPVCIGNATRVSDYVMDMGKAYEATVSIGRSTTTEDQTGDTLETKGVHSADFNKDDIDRLLENFKGVIEQIPPMYSSVKVNGKKLYEYARNNETVERPKRKVNIKDIGRISELDFKENECHFKIRVICGKGTYIRTLATDIGVKLGFPAHMSKLTRIESGGFVLKDSLTLEQIKELHEQDSLQNKLFPLEYGLKGLPSIKIKDSHIKKRILNGQKFNKNEFDNKIKDQIVFIDDDSEKVLAIYMVHPTKESEIKPKKVFN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: HNK2_XENLA
Sequence: MPLKSPFYDSSDNLIHDGWLLLRASNTPCTVLRPEIRSRFLLLSLQKPSADESPDNDKELSSNPDSGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARSEKGMEVTPLPSPRRVAVPVLVRDGKPCHTLKAQDFNPATFPTGIPFSAYSAQSLHHMQYNAQFLFYH
What is the function of this protein?
Defines dorsal-ventral domains in developing brain.  May play a role in defining positional information along the anterior-posterior (a/p) axis and the dorsal-ventral (d/v) axis of the developing nervous system.  May be involved in determining positional or boundary information rather than determining a given cell type.
What are the official names of this protein?
Homeobox protein XENK-2.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL30_THET8
Sequence: MPRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GENL2_ORYSJ
Sequence: MGVKNLWDILESCKKKLPLHHLQNKKVCVDLSCWLVQMYSANRSPAFAKDKVYLKNLFHRIRALLALNCTLLFVTDGAIPSLKLATYRRRLGSISHAAKESDQPNSHPSISLRRNKGSEFSCMIKEAKRLGMALGIPCLDGLEEAEAQCASLDLESLCDGCFTSDSDAFLFGARTVYRDVFIGEGGYVICYEMEDIEKTLGFGRNSLISLAVLLGSDYSNGVNGFGPETACRLVKSVGDNLILDQILSNGVKATRKCKGKNSGNKVDDMCPKASSCEVGMTQDSDGQFRDVINAYLEPKCHSPDSEAVQRVCGQHPFLRPQLQKICEEYFDWSPEKTDQYILPKIAERELRRFSDLRSASSALGIKPLLSEIPVPCPVLAIVKQRKVHGNECYEVSWRNIEGLQVSVVPGDLVKSACPEKITEFLEKKGEEKKQKRRARPKKSGQAAVKDVDEQLQELLLGIEADSGGILGATASVCQTLTAAYTVAVEDVVDLSSPSPPLRKLSKSQKKMMAEDVNVAGMNMNKMESESSFSTQSSTSDVDNQLIDLSSPLAGGDNGMKGGRRALADISNVGSHSTETDGGGGGGGGVASVGHGTTIDLSSPSPAIGDRSRVHHDDDDVIHERKARDLRMFLDSIRNELY
What is the function of this protein?
Single-stranded DNA endonuclease activity in vitro (PubMed:12602891).  May not be active as double-stranded DNA endonuclease (PubMed:12602891).  Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA with a specific cleavage site in the 5' overhang strand exactly one nucleotide 3' of the branch point (By similarity).  Structure- and sequence-specific nuclease that resolves holliday junctions (HJs) by symmetrically oriented incisions in two opposing strands near the junction point, thus leading to ligatable products; HJs are physical links between homologous DNA molecules that arise as central intermediary structures during homologous recombination and repair in meiotic and somatic cells (By similarity).  Probably involved in the resolution of toxic replication structures to ensure genome stability, and to maintain telomere integrity and replication (By similarity).
What are the official names of this protein?
Single-strand DNA endonuclease 1, OsSEND-1, Flap endonuclease GEN-like 2, XPG-like endonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATP23_AJECN
Sequence: MAGTNSLGAGPDTPVPSKDTGFTPGDDTWTQMKNMFSILTGNMTEEGKEQFLLARDIRNEENDCKRCEDQRDYLIKYSPIIIRFLQDNIRQLGGDISSHNIHCRRCTQRQAGGFDPQYGIRICANAMKDQGHLEDTMAHEMMHAYDHLRFKLDWTDNLRHAACTEIRASSLSGECRWAREFFRRGQWKLTQQHQECVRRRAALSVMARPACKDAEHAKQVVDEVWDSCFRDTRPFDEIYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: Y1246_PYRAB
Sequence: MEGYRLLYPMRTYLVVSGHGDEANVMAADWVTVLSFDPFMVGVAIAPKRTTHKLIKKYNEFVISVPSLEMLRDVWIAGTKKGPSKLKDMGITLVPSRKVKVPSIKEALANIECEVYDTKDYGDHTLFVGKVLAYTYKEEAFEGGKPNLKFNFLAHVSWSEFVTFQDKIYRAE
What are the official names of this protein?
Uncharacterized protein PYRAB12460.
What is the protein family that this protein belongs to?
Belongs to the flavoredoxin family.
Protein: Y2191_MYCTU
Sequence: MQGPNVAAMGATGGTQLSFADLAHAQGAAWTPADEMSLRETTFVVVDLETTGGRTTGNDATPPDAITEIGAVKVCGGAVLGEFATLVNPQHSIPPQIVRLTGITTAMVGNAPTIDAVLPMFFEFAGDSVLVAHNAGFDIGFLRAAARRCDITWPQPQVLCTMRLARRVLSRDEAPSVRLAALARLFAVASNPTHRALDDARATVDVLHALIERVGNQGVHTYAELRSYLPNVTQAQRCKRVLAETLPHRPGVYLFRGPSGEVLYVGTAADLRRRVSQYFNGTDRRKRMTEMVMLASSIDHVECAHPLEAGVRELRMLSTHAPPYNRRSKFPYRWWWVALTDEAFPRLSVIRAPRHDRVVGPFRSRSKAAETAALLARCTGLRTCTTRLTRSARHGPACPELEVSACPAARDVTAAQYAEAVLRAAALIGGLDNAALAAAVQQVTELAERRRYESAARLRDHLATAIEALWHGQRLRALAALPELIAAKPDGPREGGYQLAVIRHGQLAAAGRAPRGVPPMPVVDAIRRGAQAILPTPAPLGGALVEEIALIARWLAEPGVRIVGVSNDAAGLASPVRSAGPWAAWAATARSAQLAGEQLSRGWQSDLPTEPHPSREQLFGRTGVDCRTGPPQPLLPGRQPFSTAG
What are the official names of this protein?
Putative bifunctional exonuclease/endonuclease protein Rv2191.
Protein: KAD_THET8
Sequence: MDVGQAVIFLGPPGAGKGTQASRLAQELGFKKLSTGDILRDHVARGTPLGERVRPIMERGDLVPDDLILELIREELAERVIFDGFPRTLAQAEALDRLLSETGTRLLGVVLVEVPEEELVRRILRRAELEGRSDDNEETVRRRLEVYREKTEPLVGYYEARGVLKRVDGLGTPDEVYARIRAALGI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPYC_ARATH
Sequence: MAMEQRPKTKIVCTLGPASRSVPMVEKLLMAGMSVARFNFSHGSYEYHQETLDNLRQAMLNTGMLCAVMLDTKGPEIRTGFLKDGKPIQLKQGQEITISTDYDLKGDEKTICMSYKKLAQDVNPGMVILCADGTISLKVLSCDKEKGTVRCRCENTSMLGERKNVNLPGVVVDLPTLTEKDKQDILEWGVPNQIDMIALSFVRKGSDLVQVRKLLGKHAKTILLMSKVENQEGVANFDDILINSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNFMGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDIFKRIMLHAAVPMSPMESLASSAVRTATSSRATLMMVLTRGGSTARLVAKYRPGIPILSVVVPEITSDSFDWACSNEAPARHSLIYRGLVPVLYAGSARASIDESTEETLEFASEYGKKKQLCKTGDSVVALFRTGNAIVIKILTVK
What is the function of this protein?
Key regulatory enzyme of the glycolytic pathway that catalyzes the final step of glycolysis, converting ADP and phosphoenolpyruvate (PEP) to ATP and pyruvate by essentially irreversible transphosphorylation.
What are the official names of this protein?
Probable pyruvate kinase, cytosolic isozyme, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CYB_SIGHI
Sequence: MTNXRNEXXLLKIINHSFIDLPTPSNISSWWNFGSLLGICLMIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGIYYGSFMLHETWNIGIVLFLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDLLGVFILLMVLMFLVLFFPDILGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAAFPLLNSSKQQGLVFRPITQILYWFLVANLVILTWIGGQPVEYPFTIIGQIASISYFSIIVILXPMASTIENNIMKIYQ
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RD19C_ARATH
Sequence: MDRVVFFFLIAATLLAGSLGSTVISGEVTDGFVNPIRQVVPEENDEQLLNAEHHFTLFKSKYEKTYATQVEHDHRFRVFKANLRRARRNQLLDPSAVHGVTQFSDLTPKEFRRKFLGLKRRGFRLPTDTQTAPILPTSDLPTEFDWREQGAVTPVKNQGMCGSCWSFSAIGALEGAHFLATKELVSLSEQQLVDCDHECDPAQANSCDSGCSGGLMNNAFEYALKAGGLMKEEDYPYTGRDHTACKFDKSKIVASVSNFSVVSSDEDQIAANLVQHGPLAIAINAMWMQTYIGGVSCPYVCSKSQDHGVLLVGFGSSGYAPIRLKEKPYWIIKNSWGAMWGEHGYYKICRGPHNMCGMDTMVSTVAAVHTSPK
What is the function of this protein?
Probable thiol protease.
What are the official names of this protein?
Probable cysteine protease RD19C, RD19-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lytic vacuole. Note=Predominantly vacuolar. From the Golgi apparatus, probably transported to the lytic vacuole (LV) in clathrin-coated vesicles (CCVs) via the prevacuolar compartment (PVC).
Protein: PCKA_HISS2
Sequence: MTDLNKVINELGELGIYDVKEIVHNPSYEQLFEEETKPGLAGFEKGVVTTSGAVAVDTGIFTGRSPKDKYIVLDEKTKNTVWWTSDAAKNDNKPMNQETWQSLKGLVTKQLSGKRLFVIDAFCGANPDTRLAVRIVTEVAWQAHFVKNMFIRPSDEELQNFKPDFTVMNGSKVTNPNWKEQGLNSENFVAFNITEGVQLIGGTWYGGEMKKGMFSMMNYFLPLKGIASMHCSANVGKDGDVAIFFGLSGTGKTTLSTDPKRQLIGDDEHGWDDDGVFNYEGGCYAKTIKLSAESEPDIYRAIRRDALLENVVVREDGSVDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSKLTPEQTKYYFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMKDSGAEAYLVNTGWNGTGKRISIKDTRGIIDAILDGSIESAEMGSLPIFDLAIPKALPGVDPAILDPRDTYADKAQWQAKAEDLASRFVKNFEKYATNEEGKALIAAGPKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAR1_SCLS1
Sequence: MSAILSADDLNDFISPGVACIKPVETLPAAKPSADNELEISFNTDAPLPSDLPPAQISLTDCLACSGCVTSAEAVLVSLQSHAEVLSQLDSAPGLRLYKNATGTGIKVEGVEQGGKIYVASVSPQSRASIAATFGVTEREAGYMIEHLLSGPKGIKNRAVYRNAFQWVVDTNITREACLVLGAEEVIASMTDTGSKKPVLTSSCPGWVCYAEKTHPHVLPHLSRMKSPQALMGTLIKTTLSRKLGISPDRIWHVAVMPCFDKKLEASREELTDAVWEGTGTRGVRDVDSVITSKELLMLADSRGIEFSKLPRTPIPTSSRIPFPDTKIDSFLFPSNRKGSGNGNRDAGTSGGNLHYALHYFASQHKGSSIQTIKGRNVDVVDYTVVAENGEILLKAARYYGFRNIQNLVRRLKPAKPSRMPGGKPIGSARRPNGKASGPDYSYVEVMACPGGCTNGGGQIKVDDPINTSRLEGDAKAGPQEQKMWLAQVDEAYFSGEDNVESSSVDDRNDLVEGISPSYIKDTLSHWAATTGLDLERLVYTTYREVVSDVGKNVGDAERVIEIAGKIGGGW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.