PharMolix/UniProtQA huggingface dataset:
Protein: S35A5_PONAB
Sequence: MEKQCCSHPVICSLSTMYTFLLGAIFIALSSSRILLVKYSANEENKYDYLPTTANVCSELVKLVFCVLVSFCVIKKDHQSRNLKYASWKEFSNFMKWSIPAFLYFLDNLIVFYVLSYLQPAMAVIFSNFSIITTALLFRIVLKRRLNWIQWASLLILFLSIVALTAGTKTLQHNLAGHGFHHDAFFSPSNSCLLFRSECPRKDNCTAKEWTFPEAKWNTTARVFSHIRLGMGHVLIIVQCFISSMANIYNEKILKEGNQLAESIFIQNSKLYFFGILFNGLTLGLQRSNRDQIKNCGFFYGHNAFSVALIFVTAFQGLSVAFILKFLDNMFHVLMAQVTTVIITTVSVLVFDFRPSLEFFLEAPSVLLSIFIYNASKPQGPEYAPRQERIRDLSGNLWERSSGDGEELERLTKPKSDESDEDTF
What are the official names of this protein?
Probable UDP-sugar transporter protein SLC35A5, Solute carrier family 35 member A5.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IGLC1_HUMAN
Sequence: GQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
What is the function of this protein?
Constant region of immunoglobulin light chains.  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda constant 1, Ig lambda chain C region MGC, Ig lambda-1 chain C region.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: DHG4_PRIMG
Sequence: MYTDLKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQGDVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGSREAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIGPGAMNTPINAEKFADPVQRADVESMIPMGYIGKPEEVAAVAAFLASSQASYVTGITLFADGGMTKYPSFQAGRG
What are the official names of this protein?
Glucose 1-dehydrogenase 4, GLCDH-IV.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SYM1_BACAN
Sequence: MTEENKSFYITTPIYYPSGKLHIGHAYTTVAGDAMARYKCMQGYNVHYLTGTDEHGQKIQKKAEELNVTPQAYVDNIVAGIKELWEKMDISYDDFIRTTEDRHKDVVEKIFKQLVDQGDIYLDEYEGWYSVQDETFYTEHQLVDPIMEGDKVVGGKSPDSGHDVELVREESYFFRMGKYVDRLLKFYEDNPHFIQPESRKNEMINNFIKPGLEDLAVSRTSFDWGVRVPGNPKHVIYVWVDALSNYITALGYGTENEEMYKKFWPADVHLVGKEIVRFHTIYWPIILMALDLPLPKKVFAHGWILMKDGKMSKSKGNVVDPVILIDRYGLDALRYYLLREVPFGSDGVFTPEGFVERINFDLANDLGNLLNRTVAMIDKYFNGEIPAFKANVTEFDETLVTFAKDTLKKVEEAMENMEFSVALSSIWQLVSRTNKYIDETQPWVLAKDEDDREKLASVMAHLAEVLRQTGIMLMPFLTVAPSKMFAQLGLTDEAHTSWGSLSTIGCIPAGTKVEKGQPIFPRLEMDVEVAYIKEQMKASAPKVEEKKEEEPKAEEITIDDFFKVELRVAEVLSAEPVKKADKLLKIQLDLGTEKRQVVSGIAKFYSPEDLKGKKVICVTNLKPVKLRGELSQGMILAGEENGVLSLASIDQNIPNGTKIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase 1, Methionyl-tRNA synthetase 1, MetRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_MYCMS
Sequence: MLQPKRTKYRKPHRVSYEGKAKGVKEINFGEFGLMALDGAWIDNHQIEAARIAMTRYMKRDGKIWMRIFPHMAMTKKPAEVRMGSGKGNPEKWVAVVKKGTIMFEVAQVNEQVAREALRLAMHKLPIRCKFVKRGEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ARGR_CLOTE
Sequence: MKVTRHEKILELIERKDIETQEELAEELRKSGIEITQATVSRDIKELKLIKVLGEQGKYKYAAIVKNENDLSDKLANIFSHSVVSVENINNFVVVKTLSGSGNAAAEAIDSLNFKEIAGTIAGDNTIFIMARTSEQAFEIVKKMKRVIRERGV
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_ILLOL
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYETKETDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREASKWSPELAAACEVWREIKFEFEAMDVL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 6PGL_SALHS
Sequence: MKQTVYTASPESQQIHVWSLNHEGTLTLVQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHHGRFVFVGSYNAGNVSVTRLQDGLPVELVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTLSDDGHLVAQEPAEVNTVEGAGPRHMVFHPNRQYAYCVNELNSSVDVWQLKNPHGEIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSVEGFQPTEVQPRGFNIDNSGKYLIAAGQKSHHIAVYEITGTQGLLTEKGRYAVGQGPMWVVVNAY
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: NRDR_LISMF
Sequence: MRCPTCQYNGTRVVDSRPADDGNSIRRRRECEKCGFRFTTFEKVEESPLIVVKKDGAREEFAREKVRRGLIRACEKRPVSAEQIEEIVNEVERELRNIGDSEIASDLIGEKVMNKLANLDEVAYVRFASVYRQFKDISVFVEELKDLMEKNKDR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RNPA_LIMRD
Sequence: MRKSYRIKKESEFQRVFETHNSVANHKFVVYQMEKPGQKHFRVGISVGKKIGNAVHRNWVKRRIRQTLLEVKPQLRSDVDFLVIARSAADGLSMAETKKNLVHVLNRAHLLDEKSED
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: FDHE_SALNS
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKHWQKLLHSLIAELKPEMSGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_BACCQ
Sequence: MKLRANRVGEQMKKELGDIISRKIKDPRVGFVTVTDVQVSGDLQIATVYISVLGDEEQKESTLKGLAKAKGFIRSEIGQRIRLRKTPEISFEFDESIGYGHRIDTLLHEINKEGKREE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_THISH
Sequence: MSQPLLQSHLTSLPLIHRGKVRDLYAVGDDHLLIVTTDRVSAFDVILPTPIPGKGEVLTKISEFWFRKLEHIVPNQLADMSLAEAVPDAAERAPLEGRSLVVKRLKALPIEAVVRGYLIGSGWKDYQKTGQVCGNPLPAGLQLADRLPEPIYTPSTKAAVGDHDENVDFDYTAELVGPELAAQVRQTALALYKAAAEYALARGIIIADTKFEFGLDDEGVLHLIDEALTPDSSRFWPADTYRPGISPPSFDKQFVRDYLETLDWNKQAPGPELPPDVVQKTTEKYREALLRLTGAS
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: Y359_STRP1
Sequence: MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAIREMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK
What are the official names of this protein?
UPF0154 protein SPy_0359/M5005_Spy0302.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HOA1_CUPNH
Sequence: MFDKTKKIYVSDVTLRDGMHAIRHQYSLEQAVRIARALDVAGVDSIEVAHGDGLQGSSFNYGFGAHTDLEWIAAVADVLKHAKVATLLLPGIGTIHDLKQAYEAGARIVRVATHCTEADISKQHIEYARHLGMDTVGFLMMSHMTTPRHLAEQAMRMESYGAQCVYVVDSGGALNMYDVADRFKAFRDVLKPETQTGMHAHHNLSLGVANSIVALEHGCDRIDASLTGMGAGAGNAPLEVFIATADRMGLNHGCDVKTLIDAAEDIVRPLQERPVRVDRETLALGYAGVYSSFLRHTEVAAQRYGLSAFDILIELGKRRMVGGQEDMIVDVALDLLQRRDARGAGAH
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: TX3_SELPU
Sequence: MKTSVLFAILGLALLFCLSFGVELEETGRECGGLMTRCDGKTTFCCSGMNCSPTWKWCVYAPGRR
What is the function of this protein?
Probable ion channel inhibitor.  Shows insecticidal activity when injected into mealworms.
What are the official names of this protein?
Orally active insecticidal peptide-3, Toxin OAIP 3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 46 (Jztx-7/10/12) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DCUP_RHIWR
Sequence: MAALPAETRPLLAVLRGERRDPPPVWLMRQAGRYLPEYRALRETKGGFLELAYDSDAAAEITLQPIRRFGFDGAILFSDILIIPHAMGQDLRFEAGEGPRLSPTLVDRTLADLEPVPARLEPIYGTVRRVRAALPAETTFLGFAGSPWTVATYMVAGQGSREQAETRRKAYRDPAGFQAIIDALVDATADYLSKQIEAGVDAVQLFDSWAGSLAPREFERWVIAPTAQLVRRLHARHPGVPVIGFPKGAGGKLPAYARETGVDAVGLDETVDPAWAHANLPEGLTVQGNLDPLALVSGGEGLDTAVDAILGAFPGRPHVFNLGHGILLDTPIAHVERLLARVRG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARD1_ARATH
Sequence: MAGKRLFQDLDSDQENKSEKRIKSVLPSLASPISSVFGALISENTLRSVLEPVIRKVVRQEVEYGISKRFRLSRSSSFRIEAPEATTPTLKLIFRKNLMTPIFTGSKISDVDNNPLEIILVDDSNKPVNLNRPIKLDIVALHGDFPSGDKWTSDEFESNIIKERDGKRPLLAGEVSVTVRNGVATIGEIVFTDNSSWIRSRKFRIGAKVAKGSSGQGVVVCEAMTEAIVVRDHRGELYKKHHPPMLEDEVWRLEKIGKDGAFHKKLSSRHINTVQDFLKLSVVDVDELRQILGPGMSDRKWEVTLKHARECILGNKLYISRGPNFFMILNPICEVMKALIDGHVLSSQESLNQPYVKNLVRDAYSKGNFLEVGERTANEAALLTQGDDLDQQYAASHYQNIEIDKSYQQNGYVQERSTNNLEIVNEGYITTPAEFNICFTGSSSQNHINPF
What is the function of this protein?
Transcription activator that binds DNA in a sequence-specific manner, 5'-GAAATTTTGG-3', to promote the expression of target genes (PubMed:20921422, PubMed:21615571, PubMed:23153277).  Recruited to the promoter of ICS1 and other defense-related genes (e. g.  PR1 and SID2) in response to both biotic (e. g.  Pseudomonas syringae pv.  maculicola ES4326) and abiotic stresses (e. g.  UV-B), thus triggering slow defense responses by stimulating salicylic acid (SA) biosynthesis.  Required for basal and systemic acquired resistance to P.  syringae pv.  maculicola and Hyaloperonospora arabidopsidis (PubMed:20921422, PubMed:21615571).
What are the official names of this protein?
Protein SAR DEFICIENT 1.
What is the protein family that this protein belongs to?
Belongs to the plant ACBP60 protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEXA_ACIAC
Sequence: MLDSPKLTARQQQILDLIQTAIARTGAPPTRAEIAAEFGFKSANAAEEHLQALARKGVIELVSGTSRGIRLRGEAVRSINAARGTQFHLPIPGISQLMLPLIGRVAAGSPILAEEHVDQTYSVEGSLFQHKPDYLLKVRGMSMRDAGIMDGDLLAVQSTREARNGQIIVARLGDEVTVKRLRRTAGAIELLPENPDYPIITVQPGESFEIEGLAVGLIRNTMLM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: FBX32_MOUSE
Sequence: MPFLGQDWRSPGQSWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYSKENLFSSLNYDVAAKKRKKDIQNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNSIQISRPAFKGLTITDLPVCLQLNIMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKRLCQYHFSERQIRKRLILSDKGQLDWKKMYFKLVRCYPRREQYGVTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy.  Recognizes TERF1 (By similarity).
What are the official names of this protein?
F-box only protein 32, Atrogin-1, Muscle atrophy F-box protein, MAFbx.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and the nucleus.
Protein: EIL4_ARATH
Sequence: MVEVEELEPLSPMDDEEEEISYDDLKRRMWKDRNLMEKKLKQQKRHSNDVVSFTTHRAEASRRKKMARSQDSVLKYMMKIMEVCKAKGFVYGIVPEKGKPITGSSDSLRRWWKENVQFDQNAPDAITDYLALAAAAAAAELIDKSSSSSSLLHMLQELQDTTLGSLLSALMQHCMPPQRRFPLEKGIAPPWWPTGTELWWGEQGAAHEHGAPPYRKPHDLRKSWKVSVLAAVIKHMSPNLGRVRRLARQSKSLQDKMMAKETDTWSRVLNQEEALLNIKDLKISEDQDDQESSGSKRKSESMEPSKSVYTCQNSSCPKSDVSFGFGDKNSRTGHEIQCLYGSNQEPSQSGEYTSSLLETVPSIVTNSTSEDDYYNVSSRALDKRDDDDHSINGNWMEYFWLEKMQQEFHCSRRFEDDEGTGTDFDQLTESDRSDNVNLNQLTKSDRSDNVNRSAFSVWDMGCEDKDIYMFD
What is the function of this protein?
Putative transcription factor that may be involved in the ethylene response pathway.
What are the official names of this protein?
Putative ETHYLENE INSENSITIVE 3-like 4 protein.
What is the protein family that this protein belongs to?
Belongs to the EIN3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH60_YERE8
Sequence: MAAKDVKFGNDARIKMLRGVNILADAVKVTLGPKGRNVVLDKSFGSPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVIAAVEELKKLSVPCSDSKAIAQVGTISANSDSTVGELIAQAMEKVGKEGVITVEEGSGLQDELDVVEGMQFDRGYLSPYFINKPETGSIELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTAGTVISEEIGLELEKTTLEDLGQAKRVVINKDTTIIIDGVGDEAAIQGRVAQIRQQIEDATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRAASAITAAGLKGDNEDQNVGIKVALRAMESPLRQIVVNAGEEASVIANNVKAGSGSYGYNAYSEEYGDMIAMGILDPTKVTRSALQYAASIAGLMITTECMITDLPRDDKGADMGAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IREB2_XENLA
Sequence: MTENPFHYLVETLSGTSDKTFFNVSKLKATEYDSLPYCIRVVLEAVVRNCDGVLVKEQDAFNILNWKTKCEFKEIPFLPARVMLQDFTGIPAMVDFAAMRDAISKFGKDPKQVNPACPTDLIADHSLQLDFTKCIAAQNVSGLPAVETHRPTTTPGKTPGRKAQCRSQGGCKGACDLGAANGSSREQIENTPMLCPFHLQPIAEPETALKSLEIEFNRNKERLQFFKWCSKAFQNVAVIPPETGTVHQVNLEFLSRVVMEEKGCIYPDSVLGTDSHTTMVNGLGILGLGVGGIESEAAMLGVPITLTLPEVVGCELTGTINPIATSIDVVLSITKHLKQAGVAGTFVEFFGNGVSQLSVADRTTIANMCPEYGATVAFFPVDSVTLQHLKQTGVDLQCVKTFENYLKAVKLLRQENVQQPLYSKVLQINLNSIVPYVSGPKRPQDRISVMDMKKDFETCLKEKTGLKGFQIPEEKQNIMVPVTYGNSEYSLSHGCVVIAAVTSCTNNCNPSVMLTAGLLAKKAVEAGLTVKPYIKTSLSPGSGTVTYYLSASGVLPYLSKLGFDIIGYGCARCVGNTNPLPESIVTAIKEGELVACGVFSGNKHFEGNRCSCVCANYLASPPLVVAYALAGTVNIDLQTEPLGENAQGKKIFLQDIWPSREEVLEVEETLVIPSMFSELKLKIEKQNTRWNLLDAPESTLFPWDLRSTYIRSPPFFHKLEKIPPPIQPIERAYVLLYLGDSVTTDHMSPAGSIPRTSPAAKYLMQKNLVPREFNSYGARRGNDAVMTRGTFANMKLFNKLVGKTGPKTIHLPSGQTMDVFDAAELYQRSEIPLIIIAGKKYGLGNSRDWAAKGPFLLGVRVVIAESYEKIHKDHLVGMGIAPLQFLSGENAETLGLSGKEQYSLSLPVDLTPGHKVEIKTNTGKIFHVIAAFDNEAEVTLYKHGGILSYVARKYL
What is the function of this protein?
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA.  Binding to the IRE element in ferritin results in the repression of its mRNA translation.  Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
What are the official names of this protein?
Iron-responsive element-binding protein 2, IRE-BP 2.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_RICB8
Sequence: MTDNNIENKEEEIINDIAEEVENTEIADLKAQIEELKDKLIRASAEIDNTRKRLEKARDEARDYAITTFAKELLNVSDNLSRALEHKPLDASVEVTNIIAGVQMTKDELDKVFHKHHIEEIKPEIGSTFDYNLHNAISQIEHPDHEPNSVINIMQVGYRIKDRLLRPATVQVTKKT
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTR5_BOVIN
Sequence: MEPQDPVKREGRLTPVIVLATLIAAFGSSFQYGYNVAAINSPSEFMKDFYNYTYYDRVGEYMNEFYLTLLWSVTVSMFPFGGFLGSLMVGPLVNNLGRKGTLLFNNIFSIVPALLMGFSELAKSFEMIIVARVLVGICAGLSSNVVPMYLGELAPKNWRGALGVVPQLFITIGILVAQIFGLRSLLANEEGWPILLGLTGIPAVLQLLFLPFFPESPRYLLIQKKDEAAAKSALRRLRGWHDVDAEIEEILEEDRAEKAVGFISVLKLFKMRSLRWQVISIIVLMAGQQLSGVNAIYYYADQIYLSAGVNEDDVQYVTAGTGAVNVLITVCAIFVVELMGRRFLLLLGFSVCFTACCVLTGALALQDVISWMPYVSIACVISYVIGHALGPSPIPALLVTEIFLQSSRPAAYMVAGTVHWLSNFTVGLVFPFIQVGLGAYSFVIFAVICLLTTVYIFLIIPETKSKTFIEINRIFIKMNKVPGVHPEKEELKEFPPSTARQ
What is the function of this protein?
Functions as a fructose transporter that has only low activity with other monosaccharides.  Can mediate the uptake of deoxyglucose, but with low efficiency.  Essential for fructose uptake in the small intestine.  Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose.  Required for the development of high blood pressure in response to high dietary fructose intake.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 5, Fructose transporter, Glucose transporter type 5, small intestine, GLUT-5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma. Note=Localized on the apical membrane of jejunum villi, but also on lateral plasma membranes of the villi. Transport to the cell membrane is dependent on RAB11A.
Protein: LIPB_HERAR
Sequence: MSASTSPLIRQRGRESYEITYAAMRAFTDARTAQTADELWIVEHPPVFTLGLAADPTHVLDAHDIPVVQTDRGGEVTYHGPGQVVIYLLLDLRRNHADARIFARELVNKIEQAVIDTLAAYNLACERKAGAPGIYLSDGPLQGAKIAALGLKIRGNGCTYHGVSLNVAMDLTPFSWINPCGYEGLVTIDMQSLGAQTTLTAVQDTLAEKLTRHLSG
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTL_ECOLI
Sequence: MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWAMAMMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA
What is the function of this protein?
Confers resistance to chloramphenicol.
What are the official names of this protein?
Multidrug resistance protein MdtL.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL29_CHLFF
Sequence: MAGKKKLLAELREKSTDELDAFIHENKKALFSLRAEVGLQNKAVKTHLFSMYKKNIARSMTVKQEKEGKIDG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.