PharMolix/UniProtQA huggingface dataset:
Protein: MEND_SHESR
Sequence: MRTENTATLNLMWGALILEELARLGVQHVCMAPGSRSTPLTLAAAQQTKLKRHLHFDERGLGFMALGLAKASGAPVAIITTSGTAVANLYPAIVEAWLTHVPLIVLSGDRPPELLGCGANQAIVQPAIFANYAQQVNLPTPDAHIAPQMLLTTLDEAVANQTRPVHINCMYREPLYPSEMSGTILDSESPYLRPLQTWLQHARPYTQYGKSEQLSSPSDDAIMRFVHGKGVIIAGTLTPEQDPQQLIALAQKIGWPLLTDAQSQLRQHPAAIGNIDQLLQHPKARNLLQEADRVLVFGGRLLSKRLIAYLAEQNWHSYWQVLPQQDRLDPSHNAKHIWHANAAQFAQLNWYRSSSANWANTLVTYNDELHSLFVRNIDQGEFGEAQVIRAIANTRPLEQQLFIGNSLPVRLYDMYAPVSCCTATTYTNRGASGIDGLLATACGIAAHQGKPTSLIIGDLSQLHDLNSFTIARSLTSPLVIIILNNDGGNIFNLLPVPNEELRSDYYRLSHGLEFGYAAAMFNLPYNQVDNLADFQSCYHEALDYQGASVIEVSVSQHQASEQIAALNLWVKQS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: STF0_MYCTE
Sequence: MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT
What is the function of this protein?
Catalyzes the sulfuryl group transfer from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S).  The sulfation of trehalose is the first step in the biosynthesis of sulfolipid-1 (SL-1), a major cell wall glycolipid and the most abundant sulfated metabolite found in Mycobacterium tuberculosis, that is a potential virulence factor thought to mediate host-pathogen interactions.
What are the official names of this protein?
Trehalose 2-sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the Stf0 sulfotransferase family.
Protein: GPMA_AROAE
Sequence: MYKIVLLRHGESTWNKDNRFTGWTDVDLTEKGVEEARGAGHLLKREGYTFDLAYTSVLKRANKTLNIVLEELDSLWLPVEHSWRLNERHYGDLQGLNKAETAAKFGDDQVLVWRRSYDTPPPPLPEGDERLTSGDPRYASLPRAQFPRTECLKDTVARFVPYWETVIVPNILAGRRILIAAHGNSLRALIKYLDNISDSEIVGLNIPTAQPLVYELDANLRPIRSYYLADADTIRAAEAAVAGQGKAKG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RFC4_CAEEL
Sequence: MEEPMEVDNKRPKVLTWTEKYRPKTLDDIAYQDEVVTMLKGALQGRDLPHLLFYGPPGTGKTSAALAFCRQLFPKNIFHDRVLDLNASDERGIAVVRQKIQSFSKSSLGHSHREDVLKLKIIILDEVDAMTREAQAAMRRVIEDFSKTTRFILICNYVSRLIPPVVSRCAKFRFKSLPAEIQVQRLRTICDAEGTPMSDDELKQVMEYSEGDLRRAVCTLQSLAPILKSGDDNARNCYLRGSSDSLLISNVCKSILTADVPQIIALTKDITKSCTGVAFIRRCFQQLMDEDVINDENIGVMGKLVATCEKRILDGCDLENNLLDFLLTLRETIQ
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1.  This subunit may be involved in the elongation of the multiprimed DNA template (By similarity).
What are the official names of this protein?
Replication factor C subunit 4, Activator 1 subunit 4.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_FRATW
Sequence: MSDYKDTLNLPKTSFSMKGNLANKEPMILNKWEKQGIYKKIREHFAGREKFVLHDGPPYANGSIHVGHAVNKILKDIIIKSKTLSGYDAPFTPTWDCHGLPIELQVEKKHGKAGQSISEDDFRKECRKYAKKQVEIQKKDFKRLGVLGDWEQPYLTINFDYEANMIRTLAKIIENGHLSKGFKPVHWCTDCGSALAEAEVEYADKVSPAIDVKFKIKDKDKLAQAFGLDSLNHDAFAIIWTTTPWTLPANQAIAVNNQLNYSLIKIEDFYIILAENLVEQTLKRYAIENAQIIATTTGNKLTGIIAEHPFYSRHVPILHGDHVTDDSGTGLVHTAPTHGVDDFTLGKEHNLSMEIFVKGNGCYSENTKLFAGEFIFKANDRIIELLGEKKRLMNSDKIKHSYPHCWRHKTPLMFRATPQWFISMEKQGLRDKALQAIKETSWAPSWGQARIEGMVKDRPDWCISRQRTWGVPLPLFIHKETEELHPNTIEILHKVAEKIEKDGIEAWFNADDCEFITETAQYKSVKDTLDVWFDSGSSSMCILDLDKRLSYPADLYLEGSDQHRGWFQTSLLVAMSAKGSQPYKEVFTHGFVVDEHGRKMSKSLGNVTSPQDIYNTLGADILRLWTASTDYKSEMAVSDQILKRTADTYRRLRNTARFLLSNLDGFNPVTDIIEFDKLVKLDQWAIAKTKEFQDKIIEAYDKYQTHTVAQLIHHFCSIEMGSFYLDIIKDRQYTAKTDGHPRKSAQTAIYHIVHALVRWMAPILSFTANEIWDATPKTTDLPIQLCEWYTGLKSFDQDAELDLEYWAKIQEIRSEVNRVLEIKRNEDVIKASLEAEITIYADKYNYKLLEKLGNELRFLLISSKADLKVIEESTSSSIAANIPGLLIEITKIEEPKCERCWHRSSTVGDNPQYKDICSRCVENITTEAGESREFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPM01_PERAM
Sequence: MDAIKKKMQAMKLEKDNAMDCALLCEQQARDANLRAEKAEEEARSLQKKIQQIENDLDQTMEQLMQVNAKLDEKDKALQNAESEVAALNRRIQLLEEDLERSEERLATATAKLAEASQAVDESERARKILESKGLADEERMDALENQLKEARFMAEEADKKYDEVARKLAMVEADLERAEERAESGESKIVELEEELRVVGNNLKSLEVSEEKANLREEEYKQQIKTLTTRLKEAEARAEFAERSVQKLQKEVDRLEDELVHEKEKYKFICDDLDMTFTELAGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin Per a 7.0101, Allergen Per a 7.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: ACP_BAUCH
Sequence: MSTIEERVKIIISEQLGVKKEEVVNTASFVDDLGADSLDTVELVMALEEEFNTEIPDEEAEKITTVQAAIDFIQSSR
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2111_CLOPS
Sequence: MSENIKINEIPSGERPREKLLFYGAQCLSNEELLAIILRTGNKDSNVVELSYRIIHSVGGLNGLFKASAKELMELKGVKEAKATQILAMCELYKRFKVSELTQIKISKPSDVAKLVLDELRMLRQEVLILINLDTKNKVISKKEIFKGGLNSSLVHPREIFKEAVKDSAASIIICHNHPSGDPTPSRDDINITTRLKECGKMMGIELLDHLIIGDNRFISLKEKDIL
What are the official names of this protein?
UPF0758 protein CPR_2111.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RM46_HUMAN
Sequence: MAAPVRRTLLGVAGGWRRFERLWAGSLSSRSLALAAAPSSNGSPWRLLGALCLQRPPVVSKPLTPLQEEMASLLQQIEIERSLYSDHELRALDENQRLAKKKADLHDEEDEQDILLAQDLEDMWEQKFLQFKLGARITEADEKNDRTSLNRKLDRNLVLLVREKFGDQDVWILPQAEWQPGETLRGTAERTLATLSENNMEAKFLGNAPCGHYTFKFPQAMRTESNLGAKVFFFKALLLTGDFSQAGNKGHHVWVTKDELGDYLKPKYLAQVRRFVSDL
What are the official names of this protein?
39S ribosomal protein L46, mitochondrial, L46mt, MRP-L46, Mitochondrial large ribosomal subunit protein mL46, P2ECSL.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL46 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NAGB_HAEI8
Sequence: MRFIPLQTEQQVSCWAAQHIINRINDFKPTAERPFVLGLPTGGTPLKTYQELIRLYQAGKVSFKHVVTFNMDEYVALPEEHPESYHSFMYNNFFNHIDILPENINILNGNTDDHNAECHRYEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLSSRTRIKTLTQDTLIANSRFFNNDVTQVPKYALTIGVGTLLDAEEVMILATGHQKALAVQAAVEGSINHLWTVSALQMHRHFVLVCDEAAQQELKVKTVKYFTELEGSVAGTDYQDK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: CQ114_HUMAN
Sequence: MGLKGAWCFPWCGCRRQRGTERGAGLSPAAPPDPSPAIAPTMAEGGVPSPGPGAYFSRKARLSFRHQLHDIASANDSTI
What are the official names of this protein?
Uncharacterized protein C17orf114.
Protein: CARA_CLOPE
Sequence: MKAKLILENGVVFEGKAFGYLKECVGEVVFNTGMTGYQEVLTDPSYYGQIVTMTYPLIGNYGINLEDLESKEPKVRGFIVREKCQYPNNFRCELELETYLAQNKVLGLDGIDTRALTKILRNNGTMKGIIVLDNSNLEDVKDKLEAFSNRDAVSIVSTNEKYEISGEGKKVAIIDFGIKQNIIRNFVKRGCNVTVFPYDFKAEEVLEINPDLVFLSNGPGDPEDMGEAVNEIKKIVGKKPIVGICLGHQLLALTLGGETKKLKFGHRGCNHPVKDLINNRVHITSQNHGYYVATLPENMEITHVSMNDGTVEGMKHKELPIFSVQFHPEACPGPKDSEYIFDEFMKYAL
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: SYFB_SHIDS
Sequence: MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHGVVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLRVAVATIGAVLPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHNGIIELPADAPIGTDIREYLKLDDNTIEISVTPNRADCLGIIGVARDVAVLNQLPLVEPEIVPVGATIDDTLPITVEAPEACSRYLGRVVKGINVKAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGIVVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGEHSGVNDETQNVLLECAFFSPLSITGRARRHGLHTDASHRYERGVDPALQHKAMERATCLLIDICGGEAGPVIDITNEATLPKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPSWRFDMEIEEDLVEEVARVYGYNNIPDEPVQASLIMGTHREADLSLKRVKTLLNDKGYQEVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNRVRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESVLDLTGKLNEVEFRAEANPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVFELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPAVDILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G1L6_ORYSI
Sequence: MDRHHHHHHHHHHHMMSGGGQDPAAGDGGAGGATQDSFFLGPAAAAMFSGAGSSSSGAGTSAGGGGGGPSPSSSSPSLSRYESQKRRDWNTFGQYLRNHRPPLSLSRCSGAHVLEFLKYMDQFGKTKVHTPVCPFYGHPNPPAPCPCPLRQAWGSLDALIGRLRAAYEENGGTPEMNPFGARAVRLYLREVRETQARARGISYEKKKRKKPSSAGAGAGPSSEGSPPPPGGSASGGGDTSASPQFIIP
What is the function of this protein?
Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light.
What are the official names of this protein?
Protein G1-like6.
What is the protein family that this protein belongs to?
Belongs to the plant homeotic and developmental regulators ALOG protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IML1_CRYNB
Sequence: MEGGVLDLSLLNKDRDNVALLLYTYKPLLNNTGASANPAHPSLLPSAAASPNAPSSQVIINYAALPWNVQPGDYLEIRQINRTQPKVPTASTRIQGMEGEKPQKIKRPPALEDVKTGKGREGYVFRLGEDSPTANIHQIQVPDSVATAFGFQNRLEVEVRRIHDKESSHADYIEFYFSQYLGRADMWRLGMSLEGTTLHVGEKVSLAGGAVRAEVNFIIRDEKSKDGIAKPKRYSSGIVTAKTKTIFRSKSAQVYLFIQLCEETWQFDEDGERYVEKVVHGYLPELFARWADKGTSHVVTIIFFARIFYRDDEVDYLRKHDMVDMLSQDYSGQWYKDFFKVAVDLERRNDWMSSLPEIKRQLERSEREILLDYHLRLLKAKGAAEEEIKIVGKWCFAYQGNVLEAINLALNPFDEHYVDRDLSRTGLSITVVTPGTGHFAVDKNLLRLTTERMVDHGMSVDFVCLTKMPLHSVPLFSYVSHRPKGPVQHEDGIGAKAKPVVPDLLYFDANLSQVKDIELADCYSLPSWVSTSFYAVTHDKPFREDRFVARCKMYDIQMLGILDHNLTTVTVPLLNVDDTPMPRRPLTVDDRKAIRDSFDQSIFSGISDLVKTGSSPLDSAPASVTASYQSARLLAEKAKERTSSMSLSKPRGSDIANSSRLSPIKATSESDNIDLGKKTTPRSPSPEPSSLSLRRGSRRSLSPTKMTQLAHTSAVTNELNKDSPSLLKNSRPGSPITMARSISPVPPLPPTREQGDSPLSPVDSLPLSASVERSPSPSRRSVRSNMTDREHLGSGASTPKGTPAKSLRSQPSKGFIPSWVLNSFKPLLSTSKPSFAVPAMENVARTDVATGDDNRPSSPSPSVGSLRGRPSKGGPNPKPIITPSTPSPSRSQKPPFKPAKIIQTQPHTQAQGTQPLPIAAPPASRLPSQSEEDAISRSFRNKGHGLSRSHEDSSLRAQSNALVQSSRHFTINPCKPSAETIDRVRDAGGRRWRFVLPKLTQQHIVQWPSLIAPACLPLTTDFLPDQKQSDELYTTGTYTVQCYLEDDQFLIRSDAAETNLALAMMREMVSQRLSQNFQVIVQPHELTEPEKPRPMPIHLEKDADIGVELVSGGASEVLKKGQGAIWLSWANHIHRLLFHPTKPEIVVHWMTRKITHQTESVQWKGLVWPSGMKGYQKASATFAYPDVSMKINYNHLDHLINGERIDFAPLRYWRTRFILIPSGREPVTFPGLMPKNENLGSNDLLWLGAQKVMETLNRYLLKRPEGTPQQRSLKIVATTFDPSTCVLDEELMMDLARQIHGDSSGDKKKKLEGMTLANVAELMCQPDNGLVIRTRWWESRQHVSSFNGFELREWLQNTFEDVTGREKAQEWAAELTNKGLIEHVTKSHGFLDYWHLYYRLREPYNHMYSHLAKKEGKNKSWFSTSSKGSRAAPPSLTSSQASSSTVIAAAVADPSQATADLNTSQSGKDPSAGEQDQSSLAKIYLKVHKGEPKQGGKKRKIMMTQKRVLDLDPSRKSDRAEVAILHADVVHNARNAFHFELNWLGVTAALLEELRQKLSAQSERYGLRFVETPVEQIADIPKKCAYRTPIPIRLALAPPVIPDLHTRLVAVAHGTGQAENYFEYSILTKKFGFVLDVEATDRYPDNVEVVYSYRKAGVKYTYSQFCHKTGLALVQCVGGEAGFLWSDNRLVVSAPTRKGVGNRVDEARALRKELEDFCSDAEQLSKFYEEVLPPPPTTGESTPEEGQEEFEAKDDEEEQPAPQEKTEL
What are the official names of this protein?
Vacuolar membrane-associated protein IML1.
What is the protein family that this protein belongs to?
Belongs to the IML1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: UBID_AZOSB
Sequence: MKYEDLRDFIAQLEARGELKRIAAPVDTHLEMTEIADRVLRAGGPALLFEKPVTKGVPQAIPVLANLFGTPQRVAMGMGEDVADGDWSTPLREVGRLLSFLKEPEPPKGLKDAWEKWPVLKQVLNMAPREVRSAPCQQVVWEGDQVDLGKLPIQHCWPGDAAPLITWGLVVTRGPHKKRQNLGIYRQQVIGRNRVIMRWLAHRGGALDFREHQQAHPGEPFPVTVVLGCDPATILGAVTPVPDTISEYQFAGLLRGAKTELVKCLGSDLQVPASSEIVLEGVIHADDMAPEGPYGDHTGYYNEVADFPVFTIERITMRRDPIYHSTYTGKPPDEPAMLGLALNEVFVPLLQKQFPEITDFYLPPEGCSYRLAVVSMKKQYPGHAKRVMFGIWSFLRQFMYTKFIIVVDDDVNIRDWKEVIWAMTTRVDATRDTTLVDNTPIDYLDFASPVAGLGSKMGIDATNKWPGETNREWGRPIVMDAAVKRRVDEIWSTLGL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HPRK_STRPN
Sequence: MMSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: ESPN_MOUSE
Sequence: MALEQALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRTVQTLSLEHRVLSRDQSMDLEAKQLDSGMSSPNTTMSVQPMTFDLGSPTSTFSNYDSCSSSHSSSKGQRSNRGIPGARAADLQSYMDMLNPEKSLPRGKLGKPSPPPPPPPPPPSFPPPPPPTGTQPPPPPPGYPAPNPPVGLHLNNIYMQTKNKLRHVEVDSLKEPKVELNDQFAQPSSGDGHSGLHRQDSGLLRQDSELLHRQELLRHSTGLRRQDSDRKQRSFSKQPSTGDYYRQLGRSPGEPLAARPGMAHSEEAALLPGNHVHNGCSADSKASRELPPPPPPPPLPEALSSPPPAPPLPIEGAGAACGQRRSSSSTGKVRVLRHRKSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGSGQPASQPESPQPLVSPAPSRTRSPTPPASGSQPLLNGSVVPAPPATPAPGVHLDVEALIPTLDEQGRPIPEWKRQVMVRKLQQKMQEEEEQRRKEEEEEARLASLPAWRRDILRKKLEEEREQKRKEEERQKLEEIQRAKEQSEKLRTLGYDEAKLAPWQRQVILKKGEIPK
What is the function of this protein?
Multifunctional actin-bundling protein.  Plays a major role in regulating the organization, dimension, dynamics and signaling capacities of the actin filament-rich microvilli in the mechanosensory and chemosensory cells (PubMed:14657236, PubMed:15190118).  Required for the assembly and stabilization of the stereociliary parallel actin bundles.  Plays a crucial role in the formation and maintenance of inner ear hair cell stereocilia (PubMed:21455486).  Involved in the elongation of actin in stereocilia (PubMed:19287378, PubMed:22264607).  In extrastriolar hair cells, required for targeting MYO3B to stereocilia tips, and for regulation of stereocilia diameter and staircase formation (PubMed:26926603).
What are the official names of this protein?
Espin, Ectoplasmic specialization protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, stereocilium. Cell projection, microvillus. Cell junction. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytoskeleton. Cell projection, dendritic spine. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm, cytoskeleton. Cell projection, dendritic spine. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm, cytoskeleton. Cell projection, dendritic spine. SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasm, cytoskeleton. Cell projection, dendritic spine. SUBCELLULAR LOCATION: [Isoform 8]: Cytoplasm, cytoskeleton. Cell junction. Note=Isoform 8 localizes to parallel actin bundles of ectoplasmic specializations between neighboring Sertoli cells and at sites where Sertoli cells contact the heads of elongate spermatids.
Protein: DTDA_SULTO
Sequence: MDIRIIYSIQDAVGKTIKELGYKFEEINEDIIDFRYEKGDVIVVFSRHESSSKIPSLTVHYPGNPIDKTMGGEPKKLGIAFPSLLTSIYREIRKINIDIEKAIEATHHGPTYQHIPIIFVEIGSSKEYWENKELVKTLIEATLRGIDKYKDIECENKIVGFGGTHYTPYFSLLAEKSCVGHIISKYYLAELSNEVILQTVNNTIEKIDTVMFDNVNSKIREKIVNLLATYKLNFKFR
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: NNRE_CLAM3
Sequence: MSDPALIADGYAAADIRAAEAPLLAAGAQLMRVAAAGLARACRALAPDGPVLVLVGAGNNGGDALLAAAELAREGREVGVIRTAGRIHEAGAAQAVAAGVPITSADELDDATLADIARSSALVVDGILGIGTTDSPALRGEGRRVVAALLPVVTAEGGPAVIACDIPSGVGCDDGAVPDPAVLPADVTVTFGAGKAGLMQGPGRALAGRVELVDVGLDLSGATPLVRAAR
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: TLR2_BISBI
Sequence: MPRALWTAWVWAXIILSTEGASDQASSLSCDSTGVCDGHSRSLNSIPSGLTAGVKSLDLSNNEITYVGNRDLQRCVNLKTLRLGANEIHTVEEDSFFHLRNLEYLDLSYNRLSNLSSSWFRSLYVLKFLNLLGNLYKTLGETSLFSHLPNLXTLKVGNSNSFTEIHEKDFTGLTFLEELEISAQNLQIYVPKSLKSIQNISHLILHLKQPVLLVDILVDIVSSLDCLELRDTNLHTFHFSEASISEMSTSVKKLIFRNVQFTDESFVEVVKLFNYVSGILEVEFDDCTHDGIGDFRALSLDRIRHLGNVETLTIRKLHIPQFFLFHDLSSIYPLTGKVKRVTIENSKVFLVPCLLSQHLKSLEYLDLSENLMSEETLKNSACKDAWPFLQTLVLRQNRLKSLEKTGELLLTLENLNSLDISKNNFLSMPETCQWPGKMKQLNLSSTRIHSLTQCLPQTLEILDVSNNNLDSFSLILPQLKELYISRNKLKTLPDASFLPVLSVMRISRNIINTFSKEQLDSFQQLKTLEAGGNNFICSCDFLSFTQGQQALGRVLVDWPDDYRCDSPSHVRGQRVQDARLSLSECHRAAVVSAACCALFLVLLLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPRRDICYDAFVSYSERDSYWVENLMVQELEQFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTIFVLSENFVXSEWCKYELDFSHFRLFDENNDAAILILLEPIDKKAIPQRFCKLRKIMNTKTYLEWPVDETQQEGFWLNLRAAIRS
What is the function of this protein?
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components.  Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  May also promote apoptosis in response to lipoproteins.  Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.  Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity).
What are the official names of this protein?
Toll-like receptor 2.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Note=Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus. Triacylated lipoproteins induce the same mechanism for TLR2:TLR1 heterodimers.
Protein: RS4_BRUA1
Sequence: MSKRESAKHKIDRRLGENIWGRPKSPVNRREYGPGQHGQRRKGKLSDFGVQLRAKQKLKGFYGDISEKQFRKTYEEAARRKGDTGENLIGLLESRLDAVVYRAKFVPTIFAARQFINHGHVNVNGRRVNIQSYRLKVGDVVEVREKSKQLAIVLEAVQLAERDVPDYIDVDHNKMVATYNRVPGLSDVPYAVQMEPNLVVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: KAE1B_METBF
Sequence: MKNTFILGIEGTAWNLSAAIVTETEIIAEVTETYKPTAGGIHPREAAQHHAKYAASVIKRLLAEAKEKGVKPSDIDGIAFSQGPGLGPCLRTVATAARMLSISLGIPLIGVNHCIAHIEIGIWRTPAMDPVVLYVSGANSQVISYMGGRYRVFGETLDIGLGNALDKFARGANLPHPGGPKIEAYAKNATKYIHLPYVIKGMDLSFSGLSTAASEALKKAPLEDVCYSYQETAFAMVVEVAERALAHTGKKEVLLAGGVGANTRLREMLNDMCEARGAKFYVPEKRFMGDNGTMIAYTGLLMYKSGNTLSLEDSRVNPSYRTDDVKVTWIQEEKMKRVPEISPGTSLKLGELLDNGAEAIVYLEEGPEGKKILVKERVPKAYRYKEIDERIRTERNRTEARLMSESRRHGVSTPIIYDVEDFKLKMQYIDGVPIKYLVTPELSEKVGELVGKLHSAGIVHGDLTTSNILLAGERLYLLDFGLAYYDKGLEARGVDVHVLFQTFESTHRNHEALIEAFKKGYRRTFIDSEDVLTRVEEIKKRARYA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  The Kae1 domain likely plays a direct catalytic role in this reaction.  The Bud32 domain probably displays kinase activity that regulates Kae1 function.
What are the official names of this protein?
Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COLL1_HUMAN
Sequence: MMLPQWLLLLFLLFFFLFLLTRGSLSPTKYNLLELKESCIRNQDCETGCCQRAPDNCESHCAEKGSEGSLCQTQVFFGQYRACPCLRNLTCIYSKNEKWLSIAYGRCQKIGRQKLAKKMFF
What are the official names of this protein?
Colipase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the colipase family.
What are the subcellular locations of this protein?
Secreted.