PharMolix/UniProtQA huggingface dataset:
Protein: VCIP1_RAT
Sequence: MSQPPPPPPLPPPPPPPEAPQTSSSLAAAATPGGLSKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGRDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRPDKNYSFPLNNLVCSYDPVKDVLLPDYGLSNLTACNWCHGTSVRRVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWEGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDPSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRIGDVQGQELESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKGKAEGGPSTAAHSAHTVRQEEIAVTGKLSSKELQEQADKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYNIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASSNPHMDPRARETLAVRKHNTGTDFSNSSIKTEPPVFTAASSNSELIRIAPGVVTMRDGRQIDPDVVEAQRKKLQEMVSSIQASMDKHLRDQSTEQTPSDLSQRKVEAVSSSVRPGNLQTGLPESFSLTGGTENLNTETTDSRVADVLGAAFATRSKAQKENSMEEPEEMDSQDAETTNTTEPMDHS
What is the function of this protein?
Deubiquitinating enzyme involved in DNA repair and reassembly of the Golgi apparatus and the endoplasmic reticulum following mitosis (PubMed:12473691, PubMed:15037600).  Necessary for VCP-mediated reassembly of Golgi stacks after mitosis (PubMed:12473691, PubMed:15037600).  Plays a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (PubMed:12473691, PubMed:15037600).  Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (PubMed:12473691, PubMed:15037600).  Also involved in DNA repair following phosphorylation by ATM or ATR: acts by catalyzing deubiquitination of SPRTN, thereby promoting SPRTN recruitment to chromatin and subsequent proteolytic cleavage of covalent DNA-protein cross-links (DPCs) (By similarity).  Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Deubiquitinating protein VCPIP1, Valosin-containing protein p97/p47 complex-interacting protein 1, Valosin-containing protein p97/p47 complex-interacting protein p135, VCP/p47 complex-interacting 135-kDa protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum. Golgi apparatus, Golgi stack. Note=Associated with Golgi stacks and endoplasmic reticulum (PubMed:12473691). Displays cytoplasmic to nuclear translocation in response to DNA-protein cross-links (DPCs)- inducing agents (By similarity).
Protein: RS3_ECO5E
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: UBID_CUPPJ
Sequence: MQYKDLRDFISQLEQLGELRRVSTPVSPNLEMTEICDRLLRAGGPAVLFERPAGFRSPEGTYSVPVLANLFGTTHRVALGMGAQSLEDLRDIGRVLSALKEPEPPRGLREAGKLFTLAKSVWDMAPKRVSSPACQEIVWEGNDVDLARLPIQTCWPGDAAPLITWGLVVTKGPHKKRQNLGIYRQQVISRNQVIMRWLAHRGGALDFREHALANPGKPFPIAVALGADPATILGAVTPVPDTLSEYQFAGLLRGSRTALAGCLTPTLSELSVPASAEIVLEGHIQPDPDHPSGYQHALEGPYGDHTGYYNEQDWFPVFTIDRITMRRDPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFPEITDFYLPPEGCSYRMALVRMKKQYAGHAKRVMFGVWSFLRQFMYTKFIVVVDDDVDVRDWKEVIWAITTRVDPARDTVLVENTPIDYLDFASPVSGLGSKMGIDATDKWPGETTREWGRTISMDPAVKAKVDGMMATLFDRPAGT
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PA21_AGKPL
Sequence: MRTLWIMAVLLLGVEGDLMQFETLIMKIAKRSGMFWYSAYGCYCGWGGQGRPQDATDRCCFVHDCCYGKVTGCDPKLDSYTYSVENGDVVCGGNDPCKKEICECDRAAAICFRDNKVTYDNKYWRFPPQNCKEESEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that triggers a high neuromuscular toxicity in chick biventer cervicis preparations, but not in mouse phrenic nerve-diaphragm (PND) preparations, suggesting a selective neurotoxin activity towards birds (PubMed:28063838).  Does not induce myotoxic, coagulant, anticoagulant, edema, and antibacterial activities (PubMed:28063838).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:28063838).
What are the official names of this protein?
Acidic phospholipase A2 AplTX-I, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPC_RHOPT
Sequence: MSDILTKIEAYKREEIAAAKRERPLAAIEAIAREASPPRGFVKALRAKHAAGDYGLIAEIKKASPSKGLIRADFDPSALARAYEAGGAACLSVLTDTPSFQGSLDYLVAARAAVSLPALRKDFMYDTYQVVEARAHGADCILIIMAALDDAEAKDIEDAAFDLGMDVLLEVHDAPELERALKLRSPMVGVNNRNLRTFEVTLATSEALAPLIPKDRLMVGESGIFTPADLARLARVGMSTFLVGESLMRQQDVAAATRALLARAA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: AROA_HERAR
Sequence: MNKHYPHYLDLQPAMHAKGVVRLPGSKSISNRTLLLAALADGTTQIRDLLASDDTHVMLMALQKIGVKWEQIGESQDYVVHGVNGAFPVHQADLFMGNAGTAIRPLTAALAVTGGDYTLHGVSRMHERPIGDLVDALNAIGTHIEYTGEPGYPPLHIQRGRIHAQRMQVRGNVSSQFLTALLMAAPLMAREQDVTIDVVGELISKPYIEITLNLMRRFGVEVQRDGWQSFTIAAGQRYISPGIIHVEGDASSASYFLAAGAIAGGPVRVEGVGKNSIQGDVRFVESLQQMGATITMGDNWIEAKSNGALRAIDADFNHIPDAAMTIAVAALYADGTSTLRNIGSWRVKETDRISAMTIELRKLGASVEEGEDYLRITPPAVIQPAAIDTYDDHRMAMCFSLATLDGAIRKGSKIRINDPQCVAKTFPDYFTAFAKVTEDSLF
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_STAAR
Sequence: MNKDVSLGQPIVRYEDGKLFNTTDQYVTEFPLTIMVNGEEFATVICSPTNLEELVIGFLASEGAILKRDELKSVLIDDSKGFAHVELNKDLGDRFQYSTKRMIASCCGKSREFYFQNDAAVAKTSMSKITLTPQQIINMMTRLQSASHIYQETGGLHNAALSDGLTFFVHRQDIGRHNALDKLYGFCIQRHITVRDKVLIFSGRISSEILIKAAKIGVGVILSKSAPTTLAVTLANDLNITAVGFIRNGGFNIYSHPERIIDSEQ
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APO1B_PANTR
Sequence: MRLFLSLPVLVVVLSIVLEGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQNELSAKMREWFSETFQKVKEKLKIDS
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, basic form, Apo-CIB, ApoC-IB, Apolipoprotein C1B.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SDHD_PSEA8
Sequence: MILGTSKADWLVEFPRLADLIALRPSEWFNPAIAPSTEALADVGLGAADVADASARLQRFAPLIARLFPETAASGGIIESDLVEVATFHDALRQHYAAELPGRLWLKRDSHLPISGSIKARGGIYEVLAHAERLALEHGLVGLDDDYSRLAEADCRAFFARHRIAVGSTGNLGLSIGIIGAALGFQASVHMSADARQWKKDKLRAHGVTVVEYASDYSVAVEQGRREAAGDPYTHFVDDENSRDLFLGYAVAAERLRGQLDAAGIRVDSEHPLFVHLPCGVGGGPGGVAFGLKLAFGDAVHCLFAEPTHSPCMFLGVYTGRHEQVSVQDFGIDNRTAADGLAVGRPSGFVGRAMQRLLDGYYTVDDDELFRLLALLERSQGIRLEPSALAGAPGIARVTREPQGYRERMGLTSARLANATHLVWATGGGMVPEAEMRAYLERGRSLLD
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: RL30_NOCFA
Sequence: MADLKVTQIKSSIGAKKNQRDSLRTLGLRGIRKSVVREDNPQNRGLINVVRHLVTVEEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GLCU_STAXY
Sequence: MDLLIALLPALFWGSVVLINVLVGGGPYNQIRGTTFGALIIGIILLLTGNAKFDDLTIIIVGLISGAFWALGQGYQLKSVSLIGVSKTMPISTGLQLVGTTLFSAIFLGEWSTGVQVTLGLVAMVLLVIGIALTSIKGKNEASESSKNFGKAMPILLISTVGYVVYVVVAQIFGVDGMNALFFQSIGMAIGGLILSAKHETSVKSTLWNLIPGIVWGIGNLFMFYSQPKVGVATSFSFSQLLVIVSTLGGIFLLGEKKDKRQMIGIWAGIVLIVIAPLYSEILKHNYN
What is the function of this protein?
Involved in the uptake of glucose.
What are the official names of this protein?
Glucose uptake protein GlcU.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRKG_ECOLI
Sequence: MNTSHVRVVTHMCGFLVWLYSLSMLPPMVVALFYKEKSLFVFFITFVIFFCIGGGAWYTTKKSGIQLRTRDGFIIIVMFWILFSVISAFPLWIDSELNLTFIDALFEGVSGITTTGATVIDDVSSLPRAYLYYRSQLNFIGGLGVIVLAVAVLPLLGIGGAKLYQSEMPGPFKDDKLTPRLADTSRTLWITYSLLGIACIVCYRLAGMPLFDAICHGISTVSLGGFSTHSESIGYFNNYLVELVAGSFSLLSAFNFTLWYIVISRKTIKPLIRDIELRFFLLIALGVIIVTSFQVWHIGMYDLHGSFIHSFFLASSMLTDNGLATQDYASWPTHTIVFLLLSSFFGGCIGSTCGGIKSLRFLILFKQSKHEINQLSHPRALLSVNVGGKIVTDRVMRSVWSFFFLYTLFTVFFILVLNGMGYDFLTSFATVAACINNMGLGFGATASSFGVLNDIAKCLMCIAMILGRLEIYPVIILFSGFFWRS
What is the function of this protein?
Low-affinity potassium transport system.  Interacts with Trk system potassium uptake protein TrkA.  Requires TrkE (sapD) for maximal transport activity, low activity is seen in its absence; no further stimulation is seen with SapF (PubMed:11700350).  Transport in the absence of SapD is dependent on a high membrane potential and a high cytoplasmic ATP concentration, suggesting this protein may be able to interact with other ATP-binding proteins (PubMed:11700350).  Can transport potassium and rubidium (PubMed:7896723).
What are the official names of this protein?
Trk system potassium uptake protein TrkG.
What is the protein family that this protein belongs to?
Belongs to the TrkH potassium transport family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADEC_CERSK
Sequence: MSRSLSECIDQGRGLVPADLVLKHGRVFDLVTGELVQTDVAICGDRIVGTFGTYTGRREIDCRGRILVPGFIDTHLHVESSLVTPFEFDRCVTPRGITTAICDPHEIANVCGLEGIRYFLEASAHLVMDLRVQLSSCVPSTHMETAGAALEAKDLAPLLDHPRVIGLAEFMNFPGVLMKDPGCMAKLEAFRGRHIDGHAPLLRGKDLNGYIAAGIRTEHEATTADEALEKLRKGMRVLIREGSVSKDLHALVSILTERHAPYLCLCTDDRNPLDIAEHGHIDHMIRTAIRLGAPPLAVYRAASLSAAEAFGLKDRGLIAPGRRADIAVLDSLEGCHAALVLAGGVVADDAAFSARSGVEPVARASVKVAEIAPEAFRCPGNRAETPVIGILPGKIITEHLTAEIEPVDGDKRPDPARDLARIAVIERHGKTGGRATGFVQGFGMARGAIASTVCHDHHNLAVVGIDYADMALAANRLRALEGGFAVAAGGEILAELALPVGGLMSLRPFEEVRDALVTLREAARSLGVTLEEPFLQLAFLALPVIPHLKITDRGMVDVDRFEILP
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: RL21_ACTSZ
Sequence: MYAVFQSGGKQHRVSEGQVVRLEKLELATGETVEFDSVLMVVNGEDVKIGAPVVSGAKVVAEVVAQGRGDKVKIVKFRRRKHSRKQQGHRQWFTEVKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: EPIY_STAEP
Sequence: SLKGDDIIKGLYDLWKITKPNTLLLSIGLIFSLIGTSFSLYIPLIIRNALNKSSLSTDKIVIIIICFGLTLIFSGVSTYILGYIGQKIIQNIRSVTWNKVIKLPYSFHLKNSASNLTSRLVNDTMNITRVFSVEFIFSYSITNIFIYN
What are the official names of this protein?
Uncharacterized 16.7 kDa protein in epiA 5'region.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS1_NEIMB
Sequence: MSMENFAQLLEESFTLQEMNPGEVITAEVVAIDQNFVTVNAGLKSESLIDVAEFKNAQGEIEVKVGDFVTVTIESVENGFGETKLSREKAKRAADWIALEEAMENGDILSGIINGKVKGGLTVMISSIRAFLPGSLVDVRPVKDTSHFEGKEIEFKVIKLDKKRNNVVVSRRAVLEATLGEERKALLENLQEGSVIKGIVKNITDYGAFVDLGGIDGLLHITDLAWRRVKHPSEVLEVGQEVEAKVLKFDQEKQRVSLGMKQLGEDPWSGLTRRYPQGTRLFGKVSNLTDYGAFVEIEQGIEGLVHVSEMDWTNKNVHPSKVVQLGDEVEVMILEIDEGRRRISLGMKQCQANPWEEFAANHNKGDKISGAVKSITDFGVFVGLPGGIDGLVHLSDLSWTESGEEAVRKYKKGEEVEAVVLAIDVEKERISLGIKQLEGDPFGNFISVNDKGSLVKGSVKSVDAKGAVIALSDEVEGYLPASEFAADRVEDLTTKLKEGDEVEAVIVTVDRKNRSIKLSVKAKDAKESREALNSVNAAANANAGTTSLGDLLKAKLSGEQE
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: LEUR_YEAST
Sequence: MEGRSDFVATSQSGSEMSHSETRNRTGMNARKRKFACVECRQQKSKCDAHERAPEPCTKCAKKNVPCILKRDFRRTYKRARNEAIEKRFKELTRTLTNLTSDEILKKIEEEQEIVLDNSNFTKEKVKQLRKSAFETTEIEPRSYKTLRGEPISYSTNRRHTDSSPLTLLSSSTNFDPVHSTNVMTDDQLKCLPKSLGDVYLSSSDIAELFQEFATKYHQFLPVVDLSKGAERIYHLSPCLFWVILLIGLRRKFGATDLMTRLSVLVKSVLSEITISPIIRYTPSDKDEPVLNVASVYSVQAFLLYTFWPPLTSSLSADTSWNTIGTAMFQALRVGLNCAGFSKEYASANSELVNEQIRTWICCNVVSQTVASSFGFPAYVSFDYLVISSIRVPNSKSQVDIPNELRQMAQIARFENQIVNTMNSTPASVTGMVSQEEKQPLLHVLNQQLSQLEISLEENNLDDIRKFLLLVAKVHLLTYYFTDVTSQSAGKSNGNIYEGSYSIMELDTSFETKRGLVKVYNAAVNFLIHANSMWEHDPTIIKYFPGLFVLNIWQSACIISKLIHSSLHSMLDVNSGKKAYNNAISLTFNASVLKYDMAYRSSGIMRSIWSLFANMYDAWKNDQKEGGGRLNNDFNLGITIKSRMSVNVFFDCLYILKEKCGMAKLERETKVSTAYNVDEEEEEDEDEEGEEEEEEEELSSKVPENMDSQQLRTRKFTNVRHPEKKARKIIETIPLDPNPINAGSTSSGSSLTTPNSQVANTISYRGILNKMSPREQLNHANLDSSVSTDIKDTEAVNEPLPIGRNAEHPANQPPLSITQMQENTLPATQANSSLLETYPIVQSNPVTTTIKESPNSIMAGWDNWESDMVWRDVDILMNEFAFNPKV
What is the function of this protein?
Factor for control of RNA levels of a group of leucine-specific genes.
What are the official names of this protein?
Regulatory protein LEU3.
What are the subcellular locations of this protein?
Nucleus.
Protein: F16PA_ALIB4
Sequence: MQEIMKAIEESAIKIKHLIETGDTGKSEFENSTGDTQLKLDIASDKIIEDIFKNIPSIKAIVSEEQEAIVNLHENGKYLIAYDPLDGSSLVDVNLSVGSIFGIYENEFNAQNIVASVYVVFGPRVEMVVTTTDVKMYRLLDGKFTFIQNIKLNEKGKLNAPGSTQNCWAPFHKQLIDDIFNDGYRLRYSGGMVPDLHQILLKGGGLFSYPGTSDKPKGKLRQLFEVFPFALAYEKAGGQAVDGFKRVLEVQTTHIHDTTPCFFGSNSEINRVLEVYKKNV
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_PROM1
Sequence: MEAFSYVLILTLALVTLFFAVAFRDPPKYDK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CBXH2_CAEEL
Sequence: MSSKSTKRAKIEDPKDNVFMVEKVLDKRTGKAGRDEFLIQWQGFPESDSSWEPRENLQCVEMLDEFEREFSKREKPIRKRHSQKPEPSEDQADPEEDKDEKKETNQNDKFSLEGKQLKCIVGLTKGPGELHFLCKFSDDTARLLPAKEVNSRYPSQVIRYYESKLTIQDPKADEL
What is the function of this protein?
Seems to be involved in transcriptional silencing in heterochromatin-like complexes (PubMed:11850401).  Probably does not act as global transcriptional repressor, instead targeting a subset of genes (PubMed:23028351, PubMed:19064713, PubMed:22185090, PubMed:25467431).  Involved in RNA processing mediated by Tar DNA-binding protein homolog tdp-1 (PubMed:29760282).  Plays a role in linking epigenetic regulation with the innate immune response (PubMed:22083954).  Involved in the endoplasmic reticulum (ER) stress response via modulation of the unfolded protein response (UPR), acting mainly through the IRE1-XBP1 pathway and perhaps, to a lesser extent, through the autophagy pathway (PubMed:24715729).  May act in a common pathway with retinoblastoma-like protein homolog lin-35 and zinc finger protein lin-13 to influence the ER stress response in the intestine (PubMed:24715729).  Plays a role in the formation of the vulva and in fertility, acting together with a CoREST-like complex, and chromobox protein homolog hpl-1 (PubMed:26476455, PubMed:16905130, PubMed:16890929, PubMed:11850401).  Acting in concert with hpl-1 and histone H1 protein his-24, involved in reproduction, somatic gonad development, male tail development and vulval cell fate specification; perhaps as a result of modulating expression of Hox genes mab-5 and egl-5 (PubMed:23028351, PubMed:16905130, PubMed:16890929, PubMed:11850401, PubMed:19064713).  In vulval cell fate specification may act by repressing transcription, of EGF family gene lin-3 in hypodermal hyp7, and of homeobox lin-39 in vulval precursor cells (VPC) (PubMed:19064713).  Role in growth and somatic gonad development is antagonized by histone-lysine N-methyltransferase set-2/SET1 (PubMed:17967446).  Required for larval development, acting redundantly with hpl-1 (PubMed:16905130).  Plays a role in regulation of the developmentally arrested larval state known as dauer, longevity, and lipid metabolism (PubMed:22185090).
What are the official names of this protein?
Chromobox protein homolog hpl-2, HP1-like heterochromatin protein 2.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to distinct nuclear foci, not overlapping significantly with hpl-1, in embryonic cells (PubMed:26476455, PubMed:16905130). Localization to nuclear foci overlaps partially with zinc finger protein lin-13 (PubMed:16890929). Localizes to foci in a lin-13- dependent manner (PubMed:16890929). Localization along chromosomal arms correlates with localization of histone H3 methylated at 'Lys-9' (H3K9me), however, hpl-2 can associate with chromatin in an H3K9me- independent manner (PubMed:25467431). Localization on chromosome correlates with sequences enriched in repetitive elements, or in well- expressed genes (PubMed:25467431). Localized to gene bodies (PubMed:29760282).
Protein: GPHA2_RAT
Sequence: MPMAPRVLLFCLLGLAVTEGHGLEAAVPIPGCHLHPFNVTVRSDRHGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISSLKKVRVWLHCVGNQRGELEIFTARACQCDMCRLSRY
What is the function of this protein?
Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production.  Plays a central role in controlling thyroid cell metabolism.
What are the official names of this protein?
Glycoprotein hormone alpha-2, Putative secreted protein Zsig51, Thyrostimulin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCUP_BRUA2
Sequence: MNRKVLKVIDGETVFPPPIWMMRQAGRYLPEYRETRKKAGSFLDLCYSPDLAVEVTLQPIRRFGFDAAILFSDILVVPHALGRDLRFEEGKGPLMTPIDADEIFWLETEGVAKRLEPVYETVRLVREQLPDETTLLGFCGAPWTVATYMIAGHGTPDQAPARLFAYRFPEAFEKLLNDLADVSAEYLIEQLGAGADAVQIFDSWSGVLDEDCFERFCIRPVARIVQKVRAVYPQARIIGFPKGAGMLYAGYREKTGVDMLGLDWSVPLSFAALLQEEGAVQGNLDPLRVVAGGNALDEGVDAILERMGQGPLVFNLGHGITPQAPIENVQRMIDRVRGGKS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y934_PYRNV
Sequence: MDFSPVGEESLGVRSMCFYVETRDVRILFDAGVSLAPRRFGLPPHPRELERARAVRAEILRLAEAADVVTVSHYHRDHFTPWYPSVYMATDGEMYKRVYGGKRVLLKSPQDLNWSQRRRHYGLSKALREAGAEAVYADGGEWAFGGTRVAASPPLWHGPAGSKTGRVLGFAVSDGEERLVFLPDVEGPLEPEPIAFARGARPTVVVVGGPPTYLGWDLEKAVKNLAELVELRPHTLVLAHHLLRDVQWREKVAPLFELAERRGVVVATYASLAGRPEELLEARRRELYAEEPAAVAEAGEGEEED
What are the official names of this protein?
UPF0282 protein Tneu_0934.
What is the protein family that this protein belongs to?
Belongs to the UPF0282 family.
Protein: LILI_DROME
Sequence: MDEEEEEEVTDLKLQLFHNTVREHIIFLLLIILLYSSSYVVVSRFRRRDRDDLYSNDEDEVLVYRISFWLCTFTLAVAEGAAMLLPVSIASNEVLLLYPNSYYVKWLNSSLIQGLWNHVFLFSNLSLFIFLPFVYLFSESTGFVGNKKGILPRVYETFTVFMLMAIIVLVLTAVLSAVFGIEKLQFFWFLNLGSVHLPFLYSCVSFLGVMLMLICTPYGFVRLFGVVNQVLVRPMLLRDVNEEFSAFYMEEASVKRKLAHIELHNVSIADAANGGRLGNRIGLGRGRTFYPQPLLQHSQAHLYQRKAMASDVDELNDRLRELDSERKELDKLRTSSTFQRTFVYPLAMLLLLFCTAVTILLVVQNTLELLIGIKALPLSTRQFALGISSLSKLGPFGAGLEVCLIFYLGATSVVGFYSMPFMRKVCPKRRQTSLPQLMLNCGFMLVLSSALPLLSRIIGITNFDLLGDFGAIEWLGNFQIVLLYNLVFGTTTALCLANKFTATVRRELRARLVENYVLFTNYISFIN
What is the function of this protein?
Required during oogenesis to promote self-renewal of germline stem cells, probably by enhancing BMP signaling activity.
What are the official names of this protein?
Protein Lilipod.
What is the protein family that this protein belongs to?
Belongs to the LIMR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MDTB_SALNS
Sequence: MQVLPPGSTGGPSRLFILRPVATTLLMAAILLAGIIGYRFLPVAALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPIYSKVNPADPPIMTLAVTSNAMPMTQVEDMVETRVAQKISQVSGVGLVTLAGGQRPAVRVKLNAQAVAALGLTSETIRTAITGANVNSAKGSLDGPERAVTLSANDQMQSADEYRKLIIAYQNGAPVRLGDVATVEQGAENSWLGAWANQAPAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSQQSLRKQNRFSRACERMFDRVIASYGRGLAKVLNHPWLTLSVAFATLLLSIMLWIVIPKGFFPVQDNGIIQGTLQAPQSSSYASMAQRQRQVAERILQDPAVQSLTTFVGVDGANPTLNSARLQINLKPLDARDDRVQQVISRLQTAVATIPGVALYLQPTQDLTIDTQVSRTQYQFTLQATTLDALSHWVPKLQNALQSLPQLSEVSSDWQDRGLAAWVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTASTPGLAALETIRLTSRDGGTVPLSAIARIEQRFAPLSINHLDQFPVTTFSFNVPEGYSLGDAVQAILDTEKTLALPADITTQFQGSTLAFQAALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALIIAGSELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIFQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIAMVGGLLVSQVLTLFTTPVIYLLFDRLSLYVKSRFPRHKEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.