PharMolix/UniProtQA huggingface dataset:
Protein: ASSY_MARMM
Sequence: MSAKKPVKKVVLAYSGGLDTSVILKWLQDAYDAEVVTFTADLGQGEELEPARRKAEAAGVSEIFIEDLREEFVRDFVYPMVRANAVYEGLYLLGTSIARPLIAKRLVEIAHATGADAVAHGATGKGNDQVRFELGVYALDPDLRVIAPWREWDLNSRTKLIAYAEENGIEVAKDKRGEAPFSVDANLWHTSSEGKILEDPAEEAADIVYQRTDAPEAAPDKPEYVTIAFEAGDAVAVNGEAMSPATLLTRLNALGRVHGVGRLDLVENRFVGMKSRGIYETPGGTILMAAHRGIEQITLDRGACHLKDELMPRYAKLLYEGFWFSPEREMLQAAIDHSQKDVTGEVRLKLYKGSVNVVGRSSEHSLYSLEHVTFEEDIVYDQKDAEGFIRLNALRLQLLARRKRRLGHNE
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_ECOL6
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPDLIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKVEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPAA_PENBR
Sequence: MTNAVEDSGPRDLLFLLISTSRFNRYMPYYTMMAAESLSIEFILYKAGLCFVHCLLLCGAGNTWNDLVDRDIDARVARTKMRPLASGKVTLTEALLWMTGQYFLSVKMLDLILDGRNIWSLMLPLTASIMLYPYLKRPIFSKVFVYPQYILGLAIGYPAITGWASITGSEEPLGDIIKHCIPICLLVFFWCVYFNTAYSHQDSVDDRKMNINSAYVIAGQRIRLFLAFLSVLPLLTIPYIISTINSPWLWVSWMATWTVSIIMQIAQFDSQKLESGGRIHWDNFLLGLWTIAACMVEVGLQKVEFWKNVEGYIKL
What is the function of this protein?
Polyprenyl transferase; part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893 (PubMed:21398490).  MpaA is a Golgi apparatus-associated enzyme that catalyzes the prenylation of 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) to yield farnesyl-DHMP (FDHMP) (PubMed:21398490).  The first step of the pathway is the synthesis of 5-methylorsellinic acid (5MOA) by the cytosolic polyketide synthase mpaC.  5MOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) by the endoplasmic reticulum-bound cytochrome P450 monooxygenase mpaDE.  MpaDE first catalyzes hydroxylation of 5-MOA to 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoic acid (DHMB).  MpaDE then acts as a lactone synthase that catalyzes the ring closure to convert DHMB into DHMP.  The next step is the prenylation of DHMP by the Golgi apparatus-associated prenyltransferase mpaA to yield farnesyl-DHMP (FDHMP).  The ER-bound oxygenase mpaB then mediates the oxidative cleavage the C19-C20 double bond in FDHMP to yield FDHMP-3C via a mycophenolic aldehyde intermediate.  The O-methyltransferase mpaG catalyzes the methylation of FDHMP-3C to yield MFDHMP-3C.  After the cytosolic methylation of FDHMP-3C, MFDHMP-3C enters into peroxisomes probably via free diffusion due to its low molecular weight.  Upon a peroxisomal CoA ligation reaction, catalyzed by a beta-oxidation component enzyme acyl-CoA ligase ACL891, MFDHMP-3C-CoA would then be restricted to peroxisomes for the following beta-oxidation pathway steps.  The peroxisomal beta-oxidation machinery than converts MFDHMP-3C-CoA into MPA_CoA, via a beta-oxidation chain-shortening process.  Finally mpaH acts as a peroxisomal acyl-CoA hydrolase with high substrate specificity toward MPA-CoA to release the final product MPA (PubMed:21398490, PubMed:22544261) (Probable).
What are the official names of this protein?
Polyprenyl transferase mpaA, Mycophenolic acid biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Note=Membrane association is functionally relevant because mpaA must ostensibly interact with its membrane-embedded substrate FPP.
Protein: YNFN_ECOLI
Sequence: MREYPNGEKTHLTVMAAGFPSLTGDHKVIYVAADRHVTSEEILEAAIRLLS
What are the official names of this protein?
Uncharacterized protein YnfN.
Protein: RL13_METPB
Sequence: MKTTSLKPADVDKKWVVIDAEGLVVGRLASIVAMRLRGKHKAAYTPHVDCGDHVIVINADKVKFTGRKYDQKVYYHHTGYPGGIKERSAKFILEGRFPERVVEKAVERMLPRGPLFRQILGHLRVYKGSEHPHEAQQPQALDVGSLNRKNVSA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: HSLV_PARP8
Sequence: MEQFHGTTIVSVRRGDKVALGGDGQVTLGNIVMKGGAKKVRRIYNNKVLVGFAGGTADAFSLLDRFEAKLEKHQGNLTRAAVELAKDWRTDRMLRRLEAMLITADATTTLVITGNGDVLDPEGGICAIGSGGAYAQAAAKALADNTDLSPREIVEKSLEIAGDMCIYTNHNRVIETIE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECG_STAAN
Sequence: MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRMQWLNRLEKSSDEAIEIDYDLDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
What is the function of this protein?
Critical role in recombination and DNA repair.  Helps process Holliday junction intermediates to mature products by catalyzing branch migration.  Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity.  Unwinds branched duplex DNA (Y-DNA) (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase RecG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.
Protein: ENO_PLABA
Sequence: MAHVITRINAREILDSRGNPTVEVDLETTLGIFRAAVPSGASTGIYEALELRDNDKSRYLGKGVQQAIKNINEIIAPKLIGLDCREQKKIDNMMVQELDGSKTEWGWSKSKLGANAILAISMAICRAGAAANKTSLYKYLAQLAGKNTEKMILPVPCLNVINGGSHAGNKLSFQEFMIVPVGAPSFKEAMRYGAEVYHTLKSEIKKKYGIDATNVGDEGGFAPNILNAHEALDLLVASIKKAGYENKVKIAMDVAASEFYNIETKTYDLDFKTPNNDKSLVKTGQELVDLYIELVKKYPIISIEDPFDQDDWENYAKLTEAIGKDVQIVGDDLLVTNPTRIEKALEKKACNALLLKVNQIGSITEAIEACLLSQKNNWGVMVSHRSGETEDVFIADLVVALRTGQIKTGAPCRSERNAKYNQLFRIEESLGANGSFAGDKFRLQLN
What is the function of this protein?
Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate (By similarity).  In addition to glycolysis, involved in various processes such as parasite development and invasion (PubMed:21949403, PubMed:24474798).  Plays an essential role during ookinete invasion of the mosquito vector midgut by mediating the interaction of the ookinete with the midgut epithelium and, further, by binding to mammalian host plasminogen in the blood meal, whose conversion to active plasmin promotes the invasion process (PubMed:21949403, PubMed:24474798).
What are the official names of this protein?
Enolase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell surface. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Vacuole. Note=Partially localizes to the nucleus in rings and trophozoites. Localization to the nucleus and food vacuole is higher in early and mid-stage trophozoites compared to the late- stage trophozoites and schizonts (By similarity). In the nucleus, localizes to heterochromatin region (By similarity). In rings, nuclear localization is dependent on the actin cytoskeleton (By similarity). Localizes to the cell surface of merozoites (By similarity). In gametocytes, predominantly localizes to the actin cytoskeleton (By similarity). In the trophozoite food vacuole, colocalizes with hemozoin, a product of heme detoxification (By similarity). In sporozoites, localizes to punctate structures beneath the cell membrane (By similarity). Localizes to the cell surface of ookinetes, especially on the apical pellicle complex that is involved in invasion (PubMed:21949403, PubMed:24474798). When phosphorylated at Thr-339, localizes to the cytoskeleton (By similarity). When phosphorylated at Ser-42, localizes to the cytoplasm (By similarity). When ubiquitinated at Lys-138, acetylated at Lys-133 and Lys-375 and phosphorylated at Tyr-139, localizes to the food vacuole (By similarity). When triubiquitinated at Lys-138, appears to colocalize with hemozoin in the food vacuole (By similarity).
Protein: CYSG_SALHS
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTINALTFIPQFTVWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSDAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTERLFSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVGLRDKLNWFSNY
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: WIPI2_CHICK
Sequence: MNLAGQSGDAGSGHLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPQEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICALATIQKIPRLLVGAADGYLYMYNLDPQEGGECTLMKQHKLDGSMEPANEILESASHDRPLVAQTYSAAVTKGTYVPSSPTRHAYTEDLGAVGGACLEDETNSLRLDEDSEHPPMILRTD
What is the function of this protein?
Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation.  Involved in an early step of the formation of preautophagosomal structures.
What are the official names of this protein?
WD repeat domain phosphoinositide-interacting protein 2, WIPI-2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ILVC_ALIFM
Sequence: MSNYFNTLNLREQLDQLGRCRFMDREEFATEADYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVAYALRQAAIDEQRQSYKNAKENGFEVASYETLIPQADLVINLTPDKQHTNVVETVMPLMKEGAALGYSHGFNVVEEGMQIRKDLTVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGWDIAKAWAAGTGGHRAGCLESSFVAEVKSDLMGEQTILCGMLQAGSIVSYEKMIADGIEPGYAGKLLQYGWETITEALKFGGVTHMMDRLSNPAKVKAFELSEELKELMRPLYNKHMDDIISGEFSRTMMADWANDDVNLFGWREETGQTAFENYPESDVEISEQEYFDNGILLVAMVRAGVELAFEAMTASGIIDESAYYESLHELPLIANTVARKRLYEMNVVISDTAEYGNYLFANVATPLLREKFMPSVETDVIGRGLGESSNQVDNATLIAVNDAIRNHPVEYVGEELRSYMSDMKRIAVGG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LTXD_AGGAC
Sequence: MKTWLLALYDVLSRYKNVWNETWKIRKQLDSPVREKDENEFLPAHLELIETPVSNAPRFVSYSIMLFLTLAIIVSIFSNVEIIATASGKFALSGRSKEIKPIENSLVKHIFVKEGEYVKKGELLLKLTALGAEADTLKTKTSLSQAKLEEFRYKSLLEAVEKDQLPILDFSKIDLPFMTENDQKRVTLLIEEQFSTWQKQRHQKTLNLNKKEAEKLSYLARIKKYEGLINTEQVRLDDFRALYKEHAIAKHTVLDEENKYQDAINELEVYKASLMQVENEVLLAKEEQELVTQLFKNDILDKLKQATDNVNLLTFELDKNNQRQQVSEIRAPVSGTVQQLKVHTIDGVVTTAETLMVVVPEEDSLEVTALIQNKDIGFVKEGQEVVIKVEAFPYTRYGYLTGKVKNITLDAIEHPKLGLVFNTIIELDKKTLSTEEKEIPLSAGMEITAEIKTGMRSVISYLLSPLEESIDKSLRER
What is the function of this protein?
Involved in the export of the LtxA leukotoxin.
What are the official names of this protein?
Leukotoxin export protein LtxD.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: KLDC3_HUMAN
Sequence: MLRWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLPPVKSAIRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVPGARDGHSACVLGKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHDIRWELNAMTTNSNISRPIVSSHG
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation (PubMed:29779948, PubMed:29775578).  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms (PubMed:29779948, PubMed:29775578).  The CRL2(KLHDC3) complex specifically recognizes proteins with a glycine (Gly) at the C-terminus, leading to their ubiquitination and degradation: recognizes the C-terminal -Arg-(Xaa)n-Arg-Gly, -Arg-(Xaa)n-Lys-Gly, and -Arg-(Xaa)n-Gln-Gly degrons (PubMed:29779948, PubMed:29775578).  The CRL2(KLHDC3) complex mediates ubiquitination and degradation of truncated SELENOV and SEPHS2 selenoproteins produced by failed UGA/Sec decoding, which end with a glycine (PubMed:26138980).  May be involved in meiotic recombination process (PubMed:12606021).
What are the official names of this protein?
Kelch domain-containing protein 3, Testis intracellular mediator protein.
Protein: TLCD1_MOUSE
Sequence: MPLLFHPAWPLLLGATLTFRALRRVLCRLPQPAHVQTDPLRTWRWHNLLVSFTHSIVSGIWALLCLWQTPEMLVEIETAWSASGYLLVCFSAGYFIHDTVDIVVSKQTRASWEYLVHHVMAMGAFFSGIFWKRFVGGGVLTLLVEVSNIFLTLRMMMKINNAQDLLLYKVNKYINLVMYFLFRLAPQAYLTKFFLQYAGQRTLGTFLLAILLMLDLMIIIYFSRLLRSDFCPERAPRRQQKDKFLTE
What is the function of this protein?
Regulates the composition and fluidity of the plasma membrane (By similarity).  Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (By similarity).  Does not appear to have any effect on LCPUFA synthesis (By similarity).
What are the official names of this protein?
TLC domain-containing protein 1, Calfacilitin.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ANTR3_ARATH
Sequence: MATVGSLKPLHHSSCSSSFPRNPIVNRKALLGFVFDSARKNQIRCENLRYSSESDGKRRNAAAKKRNQSPERCAAEGVLTGGGGSEAIAEVRTMMPERIKVVILTACMMCLCNADRVVMSVAVVPLADKLGWSSSFLGVVQSSFLWGYIFSSVIGGALVDRYGGKRVLAWGVALWSLATLLTPWAAAHSTLALLCVRAFFGLAEGVAMPSMTTLLSRWFPMDERASAVGISMAGFHMGNVVGLLLTPLMLSSIGISGPFILFASLGLLWVSTWSSGVTNNPQDSPFITRSELRLIQAGKPVQPSTISPKPNPSLRLLLSKLPTWAIIFANVTNNWGYFVLLSWMPVYFQTVFNVNLKQAAWFSALPWATMAISGYYAGAASDFLIRTGHSVTSVRKIMQSIGFMGPGLSLLCLNFAKSPSCAAVFMTIALSLSSFSQAGFLLNMQDIAPQYAGFLHGISNCAGTLAAIVSTIGTGYFVQWLGSFQAFLTVTAFLYFATTVFWLLFATGERVF
What is the function of this protein?
Inorganic phosphate and probable anion transporter.
What are the official names of this protein?
Probable anion transporter 3, chloroplastic, Phosphate transporter PHT4;2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: RL1_RHIL3
Sequence: MAGKRTQKINEGVDPTKLYALTLAIGMVKERAVAKFDETIEVSMNLGVDPRHADQMVRGVVNLPNGTGRTVRVAVFARGAKADEAKAAGADIVGAEDLVEIVQGGKIEFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTMDVAGAVKASKGGAVEFRVEKAGIVHAGIGKASFDAKALEENIRAFADAVIKAKPAGAKGNYVKRVAISSTMGPGVKIEPGSVTGAPAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: GSTZ_WHEAT
Sequence: MATAKPILYGAWISSCSHRVRIALNLKGVDYEYKAVNPRTDPDYEKINPIKYIPALVDGDFVLSDSLAIMLYLEDKYPQHPLVPKDIKTKGLDLQIANIVCSSIQPLQGYGVIGLHEGRLSPDESLEVVQRYIDKGFRAIEKLLDGCDSKYCVGDEVHLGDVCLAPQIHAAINRFQIDMTKYPILSRLHDAYMKIPAFQAALPQNQPDAPSAK
What is the function of this protein?
Has a glutathione transferase activity with ethacrynic acid and nitrophenyl acetate.  Has low glutathione peroxidase activity with cumene hydroperoxide.
What are the official names of this protein?
Glutathione S-transferase, GST class-zeta.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Zeta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNAS1_PIG
Sequence: KESPAKKFQRQHMDPDSSSSNSSNYCNLMMSRRNMTQGRCKPVNTFVHESLADVQAVCSQINVNCKNGQTNCYQSNSTMHITDCRQTGSSKYPNCAYKASQEQKHIIVACEGNPPVPVHFDASV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: RAPA_SHESR
Sequence: MPFALGQRWISDTESELGLGTVVQVEGRMVTVLFPATGENRMFSRNEAPLTRVIYNPGDTVESHEGWSLSVEELTEKDGLVVYHGIHSETGEKASLRETLLNHNIRFNKPQDRLFAGQIDRLDRFGIRYQCQLLRHQLATSDLLGLQGPRVGLIPHQMWIAHEVGRRYAPRVLLADEVGLGKTIEAGLIIHQQLLTGRAERVLIIVPDTLRHQWLVEMLRRFNLRFSVFDEDRCVEAFADHDNPFYTEQLVICSLELLRKKKRLDQALDADWDLLVVDEAHHLEWTEEAPSRAYQVVEALSEVVPGVLLLTATPDQLGHESHFARLRLLDPDRFYDYDAFLAEENSYKDVAVAAEALAGDAKLSDAAINSLTELLSEKDIAPSIRLIQAEDIDSELQQAARSELLQELLDRHGTGRVLYRNSRASVKGFPKRIFNAYPHAMPEQYLTAARVNEMMGGRKTLEAKAAQALSPEKLYQEFEDNSASWWKFDPRVDWLIEFLKSHRSKKVLIIASGADTALSLEEALRTREGIQATVFHEGMSIIERDKAGAYFAQEEGGAQALICSEIGSEGRNFQFASHLVLFDLPLNPDLLEQRIGRLDRIGQQNDIQIHLPYLQDTAQERLLNWYHQGLNAFELTCPSGHVLYSEFAEDLLNVLVGGDEDELTNLLNHTQSRYKELKHAMEQGRDKLLEINSHGGDKAKAIVERLAQSDQDTKLIGSVIRLWDIIGVDQEDKGENSIILRPSEHMMFPTYPGLYEDGVTVTFDRDTALSRDDIALITQEHPLVQTGLDLITGSDTGTTSVAILKNKALPAGTLFLELIYMADASAPKSSQLYRYLPPTPIRVLLDKNGNDLSAKVDYTSFDKQLSAVNRHIGSKLVTASQPILHPLFAKGEEYAQAAVNELVAQAREKMTSQLTGELDRLESLKAVNPNIREEELEYLRNQMQELSTYLDASQLQLDAIRMVLVSHV
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: GUTR1_DROME
Sequence: MDQDMGMATGYFQDADMQMDEPAAATQSIYPHSATLFAAISACVFVTIGVLGNLITLLALLKSPTIREHATTAFVISLSISDLLFCSFSLPLTAVRFFQESWTFGTTLCKIFPVIFYGNVAVSLLSMVGITLNRYILIACHSRYSQIYKPKFITLQLLFVWAVSFLLLLPPILGIWGEMGLDEATFSCTILKKEGRSIKKTLFVIGFLLPCLVIIVSYSCIYITVLHQKKKIRNHDNFQIAAAKGSSSSGGGSYMTTTCTRKAREDNRLTVMMVTIFLCFLVCFLPLMLANVVDDERNTSYPWLHIIASVMAWASSVINPIIYAASNRNYRVAYYKIFALLKFWGEPLSPMPSRNYHQSKNSKELSGVIRSTPLFHAVQKNSINQMCQTYSV
What is the function of this protein?
Essential for the first active step of germ cell migration: transepithelial migration of germ cells through the posterior midgut (PMG) epithelium.
What are the official names of this protein?
Protein trapped in endoderm-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS13_BRUSU
Sequence: MARIAGVNIPTNKRVNIALQYIHGIGPKFAREIVTKVGIADDRRVNQLSDAEVLQIREAIDADYQVEGDLRREVSMNIKRLMDLGCYRGLRHRRSLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RIMK_SALHS
Sequence: MKIAILSRDGTLYSCKRLREAAMRRGHLVEILDPLSCYMNINPAASSIHYKGRRLPHFDAVIPRIGSAITFYGTAALRQFELLGSYPLNESVAITRARDKLRSLQLLARQGIDLPITGIAHSPDDTSDLIKMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIAEAKGCDIRCLVVGNEVVAAIERCAKAGDFRSNLHRGGVASIATITPRERDIAIKAAQTLGLDVAGVDILRAARGPLVMEVNASPGLEGIEKTTGVDIAGRMIQWIERHATPEFCLKIGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.