PharMolix/UniProtQA huggingface dataset:
Protein: APT_PARMW
Sequence: MDLQTYIRSIPDFPKPGILFRDINPLLRNPAAMVEVMRRLGAICDAVQPDLIVGIESRGFIVGTPLALQRSLGFVPVRKPGKLPGAVIGVDYALEYGTDRLEIQSDALTGNPRVLVVDDLLATGGTAAATGSLVRAAGGELVGFAFVIELEPLGGRSALPDEVLAESLIRYP
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEX1_COCP7
Sequence: MRSTSTFTRTPAFLLHTLARWLLVWGVLGSSVVAEKKCASNYYVRSLPGQPDGPLLKMHAGHVEVDHKNNGNLFFWHFQNRHIANRQRTVIWLNGGPGCSSMDGALMEIGPYRLKDDHTLIYNEGSWDEFANILFVDQPVGTGFSYVNTNSYIHELDEMASHFVTFLEKWFELFPEYEHDDLYFAGESYAGQYIPYIAKAILDRNKNTTTQAQSRLWNLKGLLIGNGWISPVEQYQAYLTYAYKENLIQSGTDAAKRVERAHSECISELDSGGKDRIHAGACEKVLSAVLEVTRENGKCINMYDIRLRDEFPSCGMNWPPDLKHITPYLRRDDVISALHVNDDKRTGWRECTGAVSSNFNARNSKPSVQLLPEILESGIPITLFSGAKDFICNHIGTEQFIHNMQWSGGTGFELSPGVWAPRHDWTFEGEAAGYYQEARNLTYVLFYNASHMVPFDFGRRSRDMLDRFLGVDITSIGGNPADSRIDGEKGALTSVGNHPNSTTAEQREKEKLKAATWAAYYKSGEVALVVVAIAAAVWGFFIWRSRRQRQGSGYRGIYPNLNGLSSGSFSGFRNKRSSHDDIEAAADFDASELDTLRGTDDRSRGANGHGSVGGDSEDEDEKFGAQKESYHPSNMPSSSSS
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: UXUA_STRSY
Sequence: MKMSFRWYGKKDPVTLEEIKAIPGMQGIVTAVYDVPVGQAWPLENILELKKMVEEAGLEITVIESIPVHEDIKQGKPNRDALIENYKTSIRNVGAAGIPVVCYNFMPVFDWTRSDLHHPLPDGSTSLAFLKSDLAGVDPVADDLNLPGWDSSYSKEEMKAIIENYRQNISEEDLWANLEYFIKAILPTAEEAGVKMAIHPDDPPYGIFGLPRIITGQEAVERFLNLYDSEHNGITMCVGSYASDPKNDVLAMTEYALKRNRINFMHTRNVTAGAWGFQETAHLSQAGDIDMNAVVKLLVDYDWQGSLRPDHGRRIWGDQTKTPGYGLYDRALGATYFNGLYEANMRAAGKTPDFGIKAKTVGTKEG
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: B2CL1_PIG
Sequence: MSQSNRELVVDFLSYKLSQKGYSWSQFTDVEENRTEAPEGTESEAETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVLNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIATWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTLAGVVLLGSLFSRK
What is the function of this protein?
Potent inhibitor of cell death.  Inhibits activation of caspases.  Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane.  Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.  Regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters.  During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles.  May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity).
What are the official names of this protein?
Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein; Cytoplasmic side. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Note=After neuronal stimulation, translocates from cytosol to synaptic vesicle and mitochondrion membrane in a calmodulin-dependent manner. Localizes to the centrosome when phosphorylated at Ser-49 (By similarity).
Protein: GMHA_BRASB
Sequence: MNRAADDLIASHLARSHAAMARAAQDTALLASAGRIAAKIVTALRSGRKLLIVGNGGSAADAQHIAAEIVGRYKQERPAFAAIALTTDTSALTAIGNDYGFDHVFARQVEGLGTSGDVLLAISTSGRSPSILNALRKARERGLTTIGFTGANGLAMGELCDELLVAPSDDTPLIQQIHLATAHGICETIEAALMQDLS
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK22_CHLRE
Sequence: MALRACSSSLVARSAARSVQPFRPAAVRPARIAPVARKTATVVCSAATDAPAAPVAEAVVGEVKSGVAHLKFQRGSADKIRRVLDVIRGRSYEEALVLCEYMPYRACEKIIKCLMSAAANAKHNKGALKTKLVVSECFADEGPVLKRARPRAQGRANLIMKPTFHMTIRVEERAQ
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFTU_COXBN
Sequence: MSKEKFVREKPHVNVGTIGHVDHGKTTLTAALTKVLSEKYGGEKKAFDQIDNAPEERARGITIATSHVEYQSDKRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHIVLAKQVGVPNIVVYLNKADMVDDKELLELVEMEVRDLLNSYDFPGDETPIIVGSALKALEGDKSEVGEPSIIKLVETMDTYFPQPERAIDKPFLMPIEDVFSISGRGTVVTGRVERGIIKVGDEIEIVGIKDTTKTTCTGVEMFRKLLDEGQAGDNVGILLRGTKREEVERGQVLAKPGSITPHKKFEAEIYVLSKEEGGRHTPFLQGYRPQFYFRTTDVTGQLLSLPEGIEMVMPGDNVKVTVELIAPVAMDEGLRFAVREGGRTVGAGVVTKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y343_BUCAP
Sequence: MFLIDSHCHIDQMNIDQKNDDLLHQEIEKILNKAYENHVKKFLTVSTSIQNFYKTKKLLSTYDSIFYSCGIHPLYCQKEIECLNELKKLSYDKCVIALGETGLDYYYSFETKNLQEKFFREHIRIAITLNKPIIIHSRNAIKDTIKILKEENAEKCGGILHSFTESEKSAFELLDMGFYISFSGIITFKKSIELCNTLKKIPLEKLLIETDSPYLAPIPYRGKKNQPAYLLDIAKKIALIKEISLKELAKITTNNFFTLFNLNF
What are the official names of this protein?
Uncharacterized metal-dependent hydrolase BUsg_343.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Protein: BIOB_NEIMA
Sequence: MTVSPVALRRKTECKPHPTARYWKKCDVEALFGLPFLDLIYQAAEIHRQNFNPREIQLSTLLSIKTGGCPEDCAYCPQSAHHNTNLGKEQMMDVDEIVEKAKIAKSRGASRFCMGAAWRGPKPKDVETVSAIIKAVKGLGMETCGTFGMLEEGMAEDLKEAGLDYYNHNLDTDPDRYNDIIHTRRHEDRMDTLGKVRNAGLKVCCGGIVGMNETRAERAGLIASLANLDPQPESVPINRLVKVEGTPLDDAEDLDWTEFVRTIAVARITMPQSYVRLSAGRSNMPEAMQAMCFMAGANSIFYGDKLLTTGNPDEDGDRILMEKLNLYPLQFELEGEVAEVEKASGIKVDY
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: HNRPF_BOVIN
Sequence: MMLGPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGVAGVHFIYTREGRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGPNSADTANDGFVRLRGLPFGCTKEEIIQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARRYIGIVKQAGLERMRSGAYSAGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRYGDGEFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQMMQGMGVSTQSTYSGLESQSVSGCYGAGYGGQNSMGGYD
What is the function of this protein?
Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm.  Plays a role in the regulation of alternative splicing events.  Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein F, hnRNP F.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: RS17_LAWIP
Sequence: MPQIIAKCNGRVLVGTVISDKNDKTIIVHVETLVKHPLLKKFIRHRKKFTAHDPLNECSIGDTVKIIEFRPLSRNKRWHLVAILEKAV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS20_BURMS
Sequence: MANSAQARKRARQAAKANSHNSALRSKFRTAIKAVRKAIDAGDQAKAAELFKAATKTIDTIADKKIVHKNKAARHKSRLSAAVKGLQAQAAQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MY9AB_DANRE
Sequence: IMSCHDVGGRRRFEDSEFTLRVYPGSLSESTIYCPVSARKVTTAAEVIERVIERLQLDRTRLYVLAEVKEFGGEEWILNPSDCPAQRMMLWPRMALENRLLGEDYRFLLREKNLDGSIHYGSLQMWLRVTEERRRMVERGLLPQPPAAQFVADLCSLPDLNEHTMLENLRGRFRQENIYTYVGSILIAVNPFKFLPIYNPKYVKMYDKHRLGQLEPHIFAVADAAYHAMLQRHRNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQESGTVRGAYVEKYLLEKSRLVYQEHNERCSCVNIFSKLVCHELKVCVCMCVQDCFSVEAEDLKHDFERLQLAMEMVGFLPTTRKQIFSLLSAILHLGNIRYKKKTFRDDSIDICNPEVLPIVSELLEVKEEMLFEALTTRKTVTVGERLIVPYKLAEVRKGTSHQLIQTFRTSHSLLHQRYFHIHTSPTRILSIGVLDIFGFEDYENNSFEQFCINFANETLQHYFNQHVFKLEQEEYRSEGINWHMIDYIDNTACINLISKKPTALLHLLDEECNFPQASNQTLLDKFKRQHEGNAYMEFPAVMEPAFIIRHYAGKVKYSVKDFREKNTDHLRPDIVSLLKSSRKAFICGLMGLDPVASFRWAVIRAFFRALVAFRHAGLQHRDNRSSSDVHLQPQKSVDSFSFLHHPVHQRSLEILQRCKDDRYNSCVSRRSPRTPLSDLQGANTFSSNGRGWRSERVSSFAHEDEGIFVNSVNNRLLERAQGILMRNKNYKPKPSLPKHLLDVKSLKYLSSLTLHDRITKSLLHLHKKKKPPSISAQFNVSLNKLMETLGQSEPYFVKCIRSNAEKLPLRFNDALVLRQLRYTGMLETVRIRQSGYSVKYSFKDFAHHFHVLLPAGFSASQMGIREFLRSADLEPSGYQVGRSMVFLHERLRQRLQDELHQEVLRRIVCLQRSFRTQRDRKHFCRQRRAARLIQRWWRSCISQADGSVCALELQQGAALRLQAVWRGFRARRLYLQQRRAVLIIQRCWRRVLNTRNTAATLIQAVWRTRTHRRSFLQQRRAAVTLQAACRGQQSRQRCRILREQQCREQSKHPSTVTKSLHQNTEEAEKLEEVWEKQTTDPPPKAVDDSTLKSRNKRESRRQRELEQATFSLELLKVRSGSNTEDAQIPPSKHHPPHQASTDSQESFELLENEDSASAKLELSKSEPMEVNQTSPAASFKPHFYIPDEDGSPINSAPQTPNRAKQIREKKESVVVIISMQKENPVDRSSLQTLEAQDVPLSNGESASDCSIIPEPRTNHELDTGSSFSVSSKPLQLDLRSAASNEEPSEPKADVQKKFVSQSISISMKETAANVAFPPKRSRLTFSKSDKDLVNQERSLAIQREAGFRSLKNRDVTRAGCKKKARMARTRSDFLSRACSTEADCEEDEDDEYEDTPVLSCTRPPHSPSSPDIDCVFHSDSEMSSQKEQKRIQKTMSSGDLGKMDSLRKSMSQTDSRVRGKMRFWSKSKHGDKKISSRGRSADSELTDRRNDSPPGSPEHAGVSERRRDSKENREPMLGMMSMKRRRSLKISSVSLESTAWQNDALHILTSTADYRSMNDFLMKKISDLDAEDGQKDTAVDVVFKKALKEFRLNIFNSYSTALAMDDGRSIRYKDLYALFEHILEKSMRLEQRDWSESPVKVWVNTFKVFLDEFMTEYKPMDGTISKAPKPERKKRRKKESDTVEEHMGHIFKSTQYSIPTYCEFCSSLIWMMDKACVCKLCRYACHKKCCLRMTTKCSKKFDPELSSRQFGVELSRLTSDERSVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELKQGLDTDANSVNLDDYNIHVIASVLKQWLRDLPNPLMTFELYEEFLRAMGLQDKREVVQGVYSIIDQLSRTHLNTLERLIFHLVRISFQEETNRMSANALAIVFAPCILRCPDTTDPLQSVRDISKTTACVELIICEQMRKYKARLKDINTLEFAENKAKSRLTHIRRSMGKSRARKSGHHTPSPPLSPRASEREEPVDEGAEPVLSEQQQAAMQQEEKVLTQQIENLQKEKEELTYEMLALEPRASDDEMLESEASIGTADSSENLMESEGAASDPWEKSPGAVSASRWRKSESKSRRCLRRQPESLDSVDSAVASLSSVSSTPHYRFRSSSSGPLFSSSSPTGDLHILPDPESCEQASLSARCASSSEKTRPRPRANRSCPPKPREPGDTGGRRREHEFGSSQPLVLYGSNEFMV
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Regulates Rho by stimulating it's GTPase activity in neurons (By similarity).  Required for the regulation of neurite branching and motor neuron axon guidance (PubMed:27259756).
What are the official names of this protein?
Unconventional myosin-IXAb, Myosin IXAb.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Cytoplasm. Synapse. Cell projection, growth cone. Note=Localized in the cytoplasm of cell bodies, dendrites and axons with occasional hints of an enrichment near the plasma membrane. Localized at the neuromuscular junction.
Protein: COBT_CITBB
Sequence: MELLESALAKIQPVDEALLTEAQAKLDNKTKPPGSLGLLEEMARRFAAITGDLSPKMGKKVIFTFAGDHGIVEEGVSLFPKEVTPQMVLNFLRGGAGVNVLARHAGAEVRVVDVGVDYDFEPTEGLIIRKIAKGTRNFAKESAMTREEAVAAIEVGIALADRAKAEGISMVGTGEMGIGNTSPSSAIIAAFAGCSVREVTHRGTGIGDQALEHKIKVIQAGLDLNRPNPEDPLDVLSKVGGLEIAGIAGLVLGAAANRIPVVVDGFISTAGALIACEMHPNVREYIFAAHNSVEIGHQMMLQRIGAKPILDLQLRLGEGTGAALAMGLIEAGVKVLNEMATFEEAGVASS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RL1_CAMJD
Sequence: MAKIAKRLKELSQKIDSNKEYALSDAIDTIKTLKSAKFDETVEIALKLNVDPRHADQMVRGSVVLPAGTGKKVRVAVIAKDAKADEAKNAGADIVGSDDLVEEIQKGNMNFDVLIATPNLMGLVGKVGRILGPKGLMPNPKTGTVTMDVAQAVNNAKSGQVNFRVDKQGNIHAGLGKVSFSKEQLWDNVSTFVKAINKHKPAAAKGRYIKNAALSLTMSPSVKLETQELLDMK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: THO5A_XENLA
Sequence: MASDSLKKRKPKVNRNEDVKRGRHEDQEGRYYSEEAEVDVRDPKEDYQLYKDTCLDLQRLMSEIQELKSKGSRDSALEIEEKKVQSCVHFMTLKKLNRLAHIRLKKARDQTHEAKQKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIELVSVEEFYSKAPVAISKPEITSTDPHQQTLSRLDWELEQRKRLAEKYKECLASKEKILKEIEIKKEYLNSLQPQLNSIMQASLPVQEYLSMPFDCMHKQYETARHLPAPLYVLFVQASAYSQACDRKLVVTIEGNVEEARALFKPPEDSQDDESDSDAEEEQTTKRRRPTLGVQLDDKRKEMLKRHPLCVTITLKCKEGSTLTLTFYFLMNLNILTVKVKILPAFELSTAISAGDLLNPDLMLSCLYQGDDGKTTPNPANQYQFDKIGILSLSDYISELGHPYIWVQAMGGLHFPTDQPQPAVVADNALSANHMEKTIKLLRTRLLSRLSLHRQFASLEHGSIPVSLECQSFFPAKVISRLTKWNVITYEDYLALPYTKDVIECGLAKETDQYFNLLIERGTAKLNGVVVLNPGYCAVPPVFSLCLNWKGERLSSNDDNIRVMESEVNVYYKELCGPPPGFQLLTNQIQRLCMLLDVYLETERHDNSVEGPHEFPPEKICLRLLRGPSRTKPFKYNYPQGFFSHR
What is the function of this protein?
May be involved in cell differentiation.
What are the official names of this protein?
THO complex subunit 5 homolog A.
What is the protein family that this protein belongs to?
Belongs to the THOC5 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm. Note=Shuttles between nucleus and cytoplasm.
Protein: KLF8_HUMAN
Sequence: MVDMDKLINNLEVQLNSEGGSMQVFKQVTASVRNRDPPEIEYRSNMTSPTLLDANPMENPALFNDIKIEPPEELLASDFSLPQVEPVDLSFHKPKAPLQPASMLQAPIRPPKPQSSPQTLVVSTSTSDMSTSANIPTVLTPGSVLTSSQSTGSQQILHVIHTIPSVSLPNKMGGLKTIPVVVQSLPMVYTTLPADGGPAAITVPLIGGDGKNAGSVKVDPTSMSPLEIPSDSEESTIESGSSALQSLQGLQQEPAAMAQMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM
What is the function of this protein?
Transcriptional repressor and activator.  Binds to CACCC-boxes promoter elements.  Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK).
What are the official names of this protein?
Krueppel-like factor 8, Basic krueppel-like factor 3, Zinc finger protein 741.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLA0_CULNU
Sequence: APHSIANGFKNLLALAATTDVDSKEAETIKEYIKDPSKIAAAAAATAPAAETKKEEKKEEKKEETEESDDDIGLSLFH
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0, Ribosomal P0 protein.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: DIRK_BUTOC
Sequence: IDCGTVMIPSECDPKSS
What is the function of this protein?
Venom protein with disintegrin activity (PubMed:30287364).  Interacts with both alpha-1/beta-1 (ITGA1/ITGB1) and alpha-v/beta-3 (ITGAV/ITGB3) with a more pronounced effect for alpha-1/beta-1 (ITGA1/ITGB1) (PubMed:30287364).  Inhibits the cell adhesion of the human glioblastoma cell line U87 and the melanoma cell line IGR39 to fibrinogen and fibronectin.  Also inhibits cell adhesion of the rat pheochromocytoma cell line PC12 to type IV collagen.
What are the official names of this protein?
RK peptide, Disintegrin-like peptide.
What is the protein family that this protein belongs to?
Belongs to the disintegrin-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRB_NEIMB
Sequence: MEVIQYPNSPFKLHQPFPPAGDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLYAEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRNDVIIVATVSAIYGIGDPTEYQQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSLIQRVGRYTVFPSSHYVTPRDTVLRACESIKEELRERIEFFAREQRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFSGKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDASRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTIFVSATPAKYEEEHAGQVVEQVVRPTGLVDPQIIIRPVATQVDDLMSEINDRIEKGERVLVTTLTKRMAEQLTDYYSELGIKVRYLHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYADKITDSMKAAIDETERRREKQIKFNEEQGIVPQQIKKQVKDIIDGVYHEEDGSKGRLKGKNKVKVGEIHNEEDAIKEIAKLEKAMQQAARDLQFEEAAVLRDRIRDIKENLLFGAE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_ARTS2
Sequence: MVYMDLNSDVGESFGRWTLGDDTAMFQSVSSANVACGFHAGDPTVIRRTCREAVQAGVMIGAHVGYRDLSGFGRRFVDIDPSELADDIVYQIGALQALAATEGARVRYVKPHGGLYNAIVSHTAQARAVVDAVKSIDASLPILGLPGSEVLRLAEAAGLRAVSEAFADRAYNPDGTLVSRSLPGAVLHDPAQVAEHVLRMAADSAIRTVDGSILRINADSICVHGDSPGAVAMAVAVRAALSDAGIDIRAFA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: BACH_HALVA
Sequence: MPAASTAATTLLQASQSEVLGEIQSNFLLNSSLWVNIALAGVVILLFVAMGRELESSRAKLIWVATMLVPLVSISSYAGLASGLTVGFLQMPPGHALAGQEVLSPWGRYLTWTFSTPMILLALGLLADTDMASLFTAITMDIGMCITGLAAALVTSSHLLRWVFYGISCAFFIAVLYVLLVEWPADAEAAGTSEIFGTLKLLTVVLWLGYPILWALGSEGVALLSVGVTSWGYSGLDILAKYVFAFLLLRWVAANEDTVTQAGMSLGSGGAAPADD
What is the function of this protein?
Light-driven chloride pump.
What are the official names of this protein?
Cruxhalorhodopsin-3, CHR-3.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DTD_PSYIN
Sequence: MIALIQRVSDARVTVAGENIGQIGPGLLVLLGVEKEDDEAKCKRLAQRVLAYRIFADGDDKMNLNVQQAGGKILVISQFTLAAQTNKGNRPGFSKGAEPIEAKRLYKLFNKNCSEMGIKVETGEFAADMQVSSTNDGPVTFWLQI
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_METKA
Sequence: MSLIEIDGSYGEGGGQILRTAVGMSALTGEPVRIYNIRANRPRPGLSHQHLHAVKAVAEICDAECEGLEIGSTEIVFEPGKVKGGEYEVDIGTAGSVTLLLQAVKLAAIAADGPVEMEVRGGTDVKWSPPVDYEINVNAHYLDRLGYRYELEVLRRGHYPRGGGIVRARMEPPKRLKPLEAVKFGELESVRGISHCVRLPPHVAERQAKAASEIIERELGIRPEIEIETYPKGRDPHLGPGSGIVLWAEDDQGNRIGADALGEKGKPAEVVGREAAEQLVQRLRTGMALDEHMGDQILPFLAIADGESVFGVTGVDPHLPTNAWVVEKFLPVSVEIRGKEGEPATVEVRPEG
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTN_ECOL6
Sequence: MNILHICVTSKWFNIDNKIVDHRP
What are the official names of this protein?
Tryptophanase operon leader peptide.
Protein: YWGA_BACSU
Sequence: MLKEHAKLMKVFSDSGEIIGRKKLQKMIYIAKKMQFPFYEKYDFHFYGPYSEELTLQIEELCNLGFLHEVKEKKGGYFQYRYSLTETGSAFLDHADLDMPDMKGYIDSVNSRSSRFLELVSTILYFDGLEDEEKKEKVFTIKSKQKYTNEEYDEALQYIEELKQIC
What are the official names of this protein?
Uncharacterized protein YwgA.