PharMolix/UniProtQA huggingface dataset:
Protein: PLD6_XENLA
Sequence: MLLWGRWKLAAGLAGLALSLELFYRYMRRRKPLREVLFFPVPVTCIEPVLSPMKQCSCPLPHTDSAFSRLLVQLLGAQRSLELCVFTFSSPSLARALLILHRRDVRVRVITDNDYMAAPGSQIGPLRSAGVAVRHDQSSGYMHHKFAVVDGTVVLTGSLNWTVQAFQSNKENILITDDTVIVKAYQKEFERLWEEYDPATYNFFPEKENK
What is the function of this protein?
Presents phospholipase and nuclease activities, depending on the different physiological conditions.  Plays a key role in mitochondrial fusion and fission via its phospholipase activity.  In its phospholipase role, it uses the mitochondrial lipid cardiolipin as substrate to generate phosphatidate (PA or 1,2-diacyl-sn-glycero-3-phosphate), a second messenger signaling lipid.  Production of PA facilitates Mitofusin-mediated fusion, whereas the cleavage of PA by the Lipin family of phosphatases produces diacylgycerol (DAG) which promotes mitochondrial fission.  Regulates mitochondrial shape through facilitating mitochondrial fusion.  During spermatogenesis, plays a critical role in PIWI-interacting RNA (piRNA) biogenesis (By similarity).  piRNAs provide essential protection against the activity of mobile genetic elements.  piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation.  Has been shown to be a backbone-non-specific, single strand-specific nuclease, cleaving either RNA or DNA substrates with similar affinity (By similarity).  Produces 5' phosphate and 3' hydroxyl termini, suggesting it could directly participate in the processing of primary piRNA transcripts (By similarity).  Has been proposed to act as a cardiolipin hydrolase to generate phosphatidic acid at mitochondrial surface.  Although it cannot be excluded that it can act as a phospholipase in some circumstances, this activity could not be confirmed (By similarity).
What are the official names of this protein?
Mitochondrial cardiolipin hydrolase, Choline phosphatase 6, Mitochondrial phospholipase, MitoPLD, Phosphatidylcholine-hydrolyzing phospholipase D6, Phospholipase D6, PLD 6.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. MitoPLD/Zucchini subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: BRF2_RAT
Sequence: MPNGSRCPDCGSSELVEDSHYSQSQLVCSDCGCVVTEGVLTTTFSDEGNLREVTYSRSTGENEQVSRSQQRDLRRVRDLCRILKLPLTFEETAVSYYQKAYQLSGIRAARLQKKEVVVGCCVLITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLADLVKSYCSSFKLFQASPSMPAKYVEDKDKMLSRTLLLVELANETWLVTGRHPLPIITAATFLAWQSLRPSDRLTCSLARFCKLANVDLPYPAASRLQELLAVLLQMASQLAWLQVLRLDKRSVVKHIGDLLQHRHMLVRMAFQDGTAEVETKQQQPQGRGQQEEVGDSTFDLPKRKRPASPALLLPPCMLKPPKRTHTMPPDSVVTGDEDISDSEIEQYLRTPQEVRDFERAQAASRAAMSVPNPP
What is the function of this protein?
General activator of RNA polymerase III transcription.  Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites.  Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress.  Down-regulates expression of target genes in response to oxidative stress.  Overexpression protects cells against apoptosis in response to oxidative stress.
What are the official names of this protein?
Transcription factor IIIB 50 kDa subunit, B-related factor 2, BRF-2.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOMPE_CHLTH
Sequence: MKKLLKSVLVFAALSSASSLQALPVGNPAEPSLMIDGILWEGFGGDPCDPCTTWCDAISMRMGYYGDFVFDRVLKTDVNKEFQMGDKPTSTTGNATAPTTLTARENPAYGRHMQDAEMFTNAACMALNIWDRFDVFCTLGASSGYLKGNSASFNLVGLFGDNENQSTVKTNSVPNMSLDQSVVELYTDTAFSWSVGARAALWECGCATLGASFQYAQSKPKVEELNVLCNAAEFTINKPKGYVGQEFPLALIAGTDAATGTKDASIDYHEWQASLALSYRLNMFTPYIGVKWSRASFDADTIRIAQPKSATAIFDTTTLNPTIAGAGDVKASAEGQLGDTMQIVSLQLNKMKSRKSCGIAVGTTIVDADKYAVTVETRLIDERAAHVNAQFRF
What is the function of this protein?
Permits diffusion of specific solutes through the outer membrane.
What are the official names of this protein?
Major outer membrane porin, serovar E, MOMP.
What is the protein family that this protein belongs to?
Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: YFJQ_BACSU
Sequence: MINITAITTEHQLLKNIPIERVEQPDIAWYWVDFYGPEDTETALLRDFFHFHPLAIEDCFQHMQRPKLDHYDGYRFYVIHALNKETLETEEVDIFQGEKFVVTFHLHETPGIAKVRERLYASPDILKKGPGHISYMIMDQLVDEYFPLVYKIEDRLNEIEESRPHKTYGTLMNEVFDLRTDLLHLRRTIIPMRDLLYRILSLDHVKEQRETKAYFSDIYDHLLKLSEIVESNRDMTSDLRDSYVTLNSNRMNAIMMTLTIVSTIFIPLTFIAGVYGMNFDFMPELHWKYGYFAVLGLMAALVIGMLIWFVHKGWFNIFK
What are the official names of this protein?
Putative metal ion transporter YfjQ.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TPIS_HORVU
Sequence: MGRKFFVGGNWKCNGTVEQVEAIVQTLNAGQIVSPDVVEVVVSPPYVFLPIVKAKLRPEIQVAAQNCWVKKGGAFTGEVSAEMLANLGVPWVILGHSERRSLLGESSEFVGEKVAYALAQGLKVIACVGETLEQREAGSTMEVVAEQTKAIAGKIKDWSNGVVAYEPVWAIGTGKVATPAQAQEVHANLRDWLKTNVSPEVAESTRIIYGGSVTGASCKELAAQADVDGFLVGGASLKPEFIDIINAAAVKSA
What are the official names of this protein?
Triosephosphate isomerase, cytosolic, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRP2A_ARATH
Sequence: MEAIDELSQLSDSMKQAASLLADEDPDETSSSKRPATFLNVVALGNVGAGKSAVLNSLIGHPVLPTGENGATRAPIIIELSRESSLSSKAIILQIDNKSQQVSASALRHSLQDRLSKGASGKNRDEINLKLRTSTAPPLKLVDLPGLDQRIVDESMIAEYAQHNDAILLVIVPASQASEISSSRALKIAKEYDPESTRTIGIIGKIDQAAENSKALAAVQALLSNQGPPKTTDIPWVAVIGQSVSIASAQSGSGENSLETAWRAESESLKSILTGAPQSKLGRIALVDTLASQIRSRMKLRLPSVLSGLQGKSQIVQDELARLGEQLVNSAEGTRAIALELCREFEDKFLLHLAGGEGSGWKVVASFEGNFPNRIKQLPLDRHFDLNNVKRVVLEADGYQPYLISPEKGLRSLIKIVLELAKDPARLCVDEVHRVLVDIVSASANATPGLGRYPPFKREVVAIASAALDGFKNEAKKMVVALVDMERAFVPPQHFIRLVQRRMERQRREEELKGRSSKKGQDAEQSLLSRATSPQPDGPTAGGSLKSMKDKPSPQDKETPEVSGLKTAGPEGEITAGYLMKKSAKTNGWSRRWFVLNEKTGKLGYTKKQEERNFRGTITLEECTIEEIPEDEVEKSKSSKDKKANGPDSKGPGLVFKITCKVPYKTVLKAHNALVLKAESVVDKNEWINKLQKVIQARGGQVGSVSMRQSLSEGSLDKMVRKPIDPEEELRWMSQEVRGYVEAVLNSLAANVPKAVVLCQVEKAKEDMLNQLYSSISAIGNERIESLIQEDQNVKRRRERYQKQSSLLSKLTRQLSIHDNRAAAASSYSDNSGTESSPRASGGSSGDDWMNAFNSAANGPSDSLSKYGSGGHSRRYSDPAQNGDAASPGSGSNRRTTPNRLPPAPPPTGSAYRY
What is the function of this protein?
Microtubule-associated force-producing protein involved in clathrin-mediated vesicle trafficking from the trans-Golgi network to the central vacuole.  Able to bind and hydrolyze GTP.  Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P).
What are the official names of this protein?
Dynamin-2A, Dynamin-like protein 6, Dynamin-related protein 2A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Localized in the forming cell plate during cytokinesis.
Protein: CAPSD_CLBVS
Sequence: MKITNDNAATINYWLAIVEPFLTSDEDRNSDDIIRKFRAVVAEHGDTEEVDPEVFFAIFSILATKYGRVYSKKVEELNESLKAAILAGAEAEDLRNKLKDISQRYASQLEITADREQQLESLKKKGHEQPLTGSGSSEPVHAESAHAPQLHVVNDLQQFYIPFNEYPSLTQSIGTSDIANDEHLKRVQLTLKITDTKVFSRTGFEFAISCGSRSTSDKDPYDGIIKISGKSHMRKDIAYAIRTSGITVRQFCAAFANLYWNFNLARNTPPENWRKKGFTEGTKFAAFDFFYAVGSNAAIPTEADGSVRLIRPPTNEENEANSAMRYADIYEQNSKTAGHVTSSPLYNRGSSYESKNKAKLLEM
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What are the subcellular locations of this protein?
Virion.
Protein: RNF41_PONAB
Sequence: MGYDVTRFQGDVDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNMLSKLQIACDNAVFGCSAVVRLDNLMSHLSDCEHNPKRPVTCEQGCGLEMPKDELPNHNCIKHLRSVVQQQQTRIAELEKTSAEHKHQLAEQKRDIQLLKAYMRAIRSVNPNLQNLEETIEYNEILEWVNSLQPARVTRWGGMISTPDAVLQAVIKRSLVESGCPASIVNELIENAHERSWPQGLATLETRQMNRRYYENYVAKRIPGKQAVVVMACENQHMGDDMVQEPGLVMIFAHGVEEI
What is the function of this protein?
Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins.  Polyubiquitinates MYD88.  Negatively regulates MYD88-dependent production of pro-inflammatory cytokines.  Can promote TRIF-dependent production of type I interferon and inhibits infection with vesicular stomatitis virus.  Promotes also activation of TBK1 and IRF3.  Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors.  Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hematopoietic progenitor cell differentiation into myeloerythroid lineages.  Contributes to the maintenance of steady-state ERBB3 levels by mediating its growth factor-independent degradation.  Involved in the degradation of the inhibitor of apoptosis BIRC6 and thus is an important regulator of cell death by promoting apoptosis.  Acts also as a PRKN modifier that accelerates its degradation, resulting in a reduction of PRKN activity, influencing the balance of intracellular redox state.  The RNF41-PRKN pathway regulates autophagosome-lysosome fusion during late mitophagy.  Mitophagy is a selective form of autophagy necessary for mitochondrial quality control.
What are the official names of this protein?
E3 ubiquitin-protein ligase NRDP1, RING finger protein 41, RING-type E3 ubiquitin transferase NRDP1.
Protein: A1CF_PONAB
Sequence: MESNHKSGDGLSGTQKEAALRALIQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKLEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHPIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQAYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAYVDEAKTYAAEYTLQTLGIPTDGGDAGTMATAAAVATAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGAF
What is the function of this protein?
Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA.  Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine.  The complex also seems to protect the edited APOB mRNA from nonsense-mediated decay (By similarity).
What are the official names of this protein?
APOBEC1 complementation factor, APOBEC1-stimulating protein.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum. Cytoplasm. Note=Predominantly nuclear where it localizes to heterochromatin. Also cytoplasmic where it is found at the outer surface of the endoplasmic reticulum. Shuttles between the nucleus and cytoplasm. May be transported into the nucleus by the nuclear import protein TNPO2/TRN2 or by APOBEC1 (By similarity).
Protein: RPN2_CHICK
Sequence: NAIFSKKNFETLSEAFSVFQTLKYLAILGGVTFLAG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 65-II kDa subunit, Ribophorin II, RPN-II, Ribophorin-2.
What is the protein family that this protein belongs to?
Belongs to the SWP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi- pass membrane protein.
Protein: NSP4_WTV
Sequence: MKQVAGFIGMSQKNKGIQQNQWHSGPPQGLLSGQTKAEQGTSSQQAGVNQGENSKSGAVVQRKMPMRRDVNSAAQRQHVRRLVYTPYFPNETWNISTFKNGAKDVERSVISTLNNVAENRVMDNCTSRVIFEMTQIQFESLPDIIRNEFTRVGDDALKWAVPEDLKSADLDHMMVVKLSTEGTIYPTTLIFPGGCSGMAKLKSVYSFLESQLERIVTPTPSVSLKYVTSWAEHLFDLCSGQLINSQNERVDKLLGYMIWDIEKAITLTDQVIACYNHPEVVLRRLGASDIACAVLAGESVVKLTRLALSKSPVDGCSCCRILELILNLPSRKPNDKVPQVPLDILFASVYRYVSAMCMGRVLNGRIDASGIQSTDHATASIKLNDIIVNDLELRSMGVDKTSSFRGTQSMRAFYVPENLAGSILDRINVLVMRHFGILHMWGFNGVVLQNQEGYCDYHIITGLNHLTTITHTNSMVAVHWGTESRMDNIFEIKARTLPTASETMITLIENALKEQLTSIVKDGLRKGVSFSVKRNINDSRFGFETNSSPAIFLKLRDMLKRAKPFSDLLSLALSKVIKKENAMIQRSITTVEVAVAIKMKVYGLDEYVSLMKVEKKEVESGSLPLQEFLKLKSNAAGAQSSTVAVKMKEEEVNSKAYCLISETIVVNMDAVRSACGVVQSENLVIKSELSGPELSESVTSGLMELLGRNAGPSKSWADQVEEAENEEEKQKE
What are the official names of this protein?
Non-structural protein 4, Pns4.
Protein: NMO_STAA9
Sequence: MWNKNRLTQMLSIEYPIIQAGMAGSTTPKLVASVSNSGGLGTIGAGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSSQIENMNAWLKPYRRALHLEEPVVKIIEEQQFKCHIDTIIKKQVPVCCFTFGIPNESIIERLKEANIKLIGTATSVDEAIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMVGTISLVPQIVDVVSIPVIAAGGIMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVVTKAFSGKLARGINNRFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELTHMWSGQSPRLATTHPANTIMSNIINQINQIMQYK
What is the function of this protein?
Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates.  Acts on propionate 3-nitronate (P3N), the presumed physiological substrate.  Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.
What are the official names of this protein?
Probable nitronate monooxygenase, NMO, Propionate 3-nitronate monooxygenase, P3N monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the nitronate monooxygenase family. NMO class I subfamily.
Protein: ACR22_ORYSJ
Sequence: MARGVSYVSAAQLVPMLRDPRIAVVDVRDEERIYDAHIAGSHHYASDSFGERLPELAQATKGKETLVFHCALSKVRGPSCAQMYLDYLSEADEDSDVKNIMVLERGFNGWELSGRPVCRCKDAPCKGVCS
What is the function of this protein?
Possesses phosphatase activity towards p-nitrophenyl phosphate in vitro.
What are the official names of this protein?
Arsenate reductase 2.2, OsACR2.2, Dual specificity phosphatase CDC25.2, Sulfurtransferase 21, OsStr21.
Protein: DER_STRZP
Sequence: MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: CTSR4_MOUSE
Sequence: MSEKHKWWQQVENIDITHLGPKRKAYELLGRHEEQVLINRRDVMEKKDAWDVQEFITQMYIKQLLRHPAFQLLLAFLLLSNAITIALRTNSYLGQKHYELFSTIDDIVLTILICEVLLGWLNGFWIFWKDGWNILNFAIVFILFMGFFIKQLDMVAITYPLRVLRLVHVCMAVEPLARIIKVILQSMPDLANVMALILFFMLVFSVFGVTLFGAFVPKHFQNMGVALYTLFICITQDGWLDIYTDFQMDEREYAMEVGGAIYFAVFITLGAFIGLNLFVVVVTTNLEQMMKTGEEEGHLNIKFTETEEDEDWTDELPLVHCTEARKDTSTVPKEPLVGGPLSNLTEKTCDNFCLVLEAIQENLMEYKEIREELNMIVEEVSSIRFNQEQQNVILHKYTSKSATFLSEPPEGANKQDLITALVSREKVSDSNINMVNKHKFSH
What is the function of this protein?
Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation.  Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization.  Activated by intracellular alkalinization.
What are the official names of this protein?
Cation channel sperm-associated protein 4, CatSper4.
What is the protein family that this protein belongs to?
Belongs to the cation channel sperm-associated (TC 1.A.1.19) family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specifically located in the principal piece of the sperm tail.
Protein: HISZ_AZOSB
Sequence: MRWVLPDHIQDALPSEAASLEALRRRLLDAFRVRGYQLVMPPLLEYLDSLTTGAGQDLKLRTFKLVDQVSGRTMGVRADMTPQVTRIDAHLLNRAGVSRLCYCGSVLHTLPSTLTATREPLQLGAELYGHAGIDADIEIVRLLADVLRLAEVPASRIDIGHVGLFHALAALAGMVPEREEELFDLLQAKDVPGLKEITVGVAEPVRTALLRLPALYGGAEVIDEAAACMPESAEIRAALDDLRRLAAALEDLPISFDLADLRGYHYHSGVVFAAYGGGSPAALALGGRYDRVGEAFGRARPATGFSLDLRELALRLPAAVVPGAILAPLEGTAGLAAAVEALRAAGEAVMSRLPGHEGTWNDAGCDRQLVMRQGAWVVEPLQGE
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_XANCP
Sequence: MADQKIRIRLKAFDHRLIDRSASEIVETAKRTGAQVRGPIPLPTKIERYTILVSPHADKDARDQYETRTHKRVLDIVDPNDKTVDALMKLELAAGVDVQIKLT
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RPOE_ALKCK
Sequence: MDLQSLTKEELNEMSMVEAAFIVMANKRQPFNFYDLLEEVAKLKGISETEMDERISFLYTDLNLDGRFLTLGDNTWGLRSWYPHEQAEEEITHSAKPAKRRKSGDDDGEEEYDLVDELEEDEFEDLEDELDELADEEDQDGERDDYDEKDDALPGFDEEDGQTLDEED
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: MOAA_PSESM
Sequence: MSEPVLMDRFARKVDYLRMSVTDRCDFRCVYCMAEEMTFLPRQQILSLEEIHQVAERFVALGTRKIRLTGGEPLVRAGVVGLCEKIAALPGLRELCMTTNGSQLDKLAAPLFKAGVTRLNISLDSLDPQRFRELTRTGDLHKVIAGIDAANAAGFVHTKLNCVVMHGRNDHEINDLLAFAIDRNLDVSFIEEMPLGIISEHSRAESFYSSDQVRERIAERYTLIPSTDSTQGPSRYWRLAQAPGIRIGFISPHSHNFCGTCNRVRLTVEGRLLLCLGNEHSVDLKAVLRATPGQPEKLEKAIIDAMQLKPWSHNFTHDDGVQVVRFMNMTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: DXR_RHIEC
Sequence: MTTGKTAPRRLSIFGSTGSIGRNTLNVIEHLGGRENFEISVLTGNGNVELLARQARSSGARLAVTASDRHYESLKRELSGSGIAVASGKSGLMEAADRDADWVMAAIVGTAGLAPTLAAARRGADIALANKECLVSAGDLFIKAIREGGGRLLPVDSEHNAIFQVLEENQRHAIERVILTASGGPFRNASLEEMKHVTAETARAHPNWSMGLKISIDSASMFNKALEMIEARHLFSLNPDQIEVIFHPQSIIHSMVGYTDGSVLAQLGAPDMRTAIGYALSFPRRPKLPVERLDFAKLARLDFEAPDEVRFPALRLAHLAMTRGGVQGAVLNGAKEVALEAFIEGRLAFLAMAEITERVMDDLAHLPPAAGMDDVFSADRQARQRAAELMKLDLVG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GLMM_RHIL3
Sequence: MKRRYFGTDGIRGQSNVFPMTPDLAMRVGIAAGTIFRRGNHRHRVVIGKDTRLSGYMLENAMVAGFTAAGLDAFILGPIPTPAVAMLTRSLRADLGVMISASHNPYEDNGIKLFGPDGYKLSDDIEAEIEDLLERDLNAQLAKSDDIGRAKRVDGVHDRYIEHAKRTLPRDVTLQGLRIAIDCANGAAYKVAPAVLWELGAEVVTIGNEPNGTNINLNCGSTSPVALQKKVDEVRADIGIALDGDADRVIIVDENGSIVDGDQLMAVIAESWAESQQLRGNGIVATVMSNLGLERFLDDKGLGLARTKVGDRYVVEHMRQHNYNVGGEQSGHIVLSDYGTTGDGLVAALQILAAVKRTGRTVSEVCRRFEPVPQLLRNVRISGGKPLEDIQVQKAIADAEAELARNGRLVIRPSGTEPLIRVMAEGDDRAQIERIVNELIGTISNVRTAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MSBA_HAES1
Sequence: MQDKDLSTLQTFKRLWPTIAPFKLGLIASAVALVFNALADAALIQMLKPVLDEGFGKVDNSLLRIMAIVVVLLIFVRGVTNFISTYCLAWVSGKVVMVMRRRLFRHLMYMPVTFFDQNSVGRLLSRIVYDSEQVANSSSGSLVTIVREGAYIIALLTVMFYTSWQLALVLFIIGPIIAVIIRIVSKKFRELGKNLQNSMGDLTSSVEQMLKGHKVVLAFGGQKIEEERFDQVSNNMRRRGMKVMAASAISDPVVQIIASFALAAVLFLATLPEIMTQNLSAGSFTVVFSSMLAMMRPLKSLTNVNAQFQRGMAACQTLFALLDLETEKDTGKHVVDTVKGEVRFENVTFSYSGKEHPALNNISFTIPQGKTVALVGRSGSGKSTIANLVTRFYDVEQGKITLDGVNIQDYTLANLREHCAVVSQQVHLFNDTIANNIAYAVTEKCTREQIIEAAEAAYAMEFIEKLENGLDTVIGENGASLSGGQRQRLAIARALLRDSPVLILDEATSALDTESERAIQAALETLQKDRTVLVIAHRLSTIEKADEILVIEQGEIKERGSHQELLALNGAYKQLHSTQFNH
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXC_HAES1
Sequence: MIKQRTLKQSIKVTGVGLHSGNKVTLTLRPAMPNTGVIYCRTDMNPPVTFPANANAVRDTMLCTCLINEDGVRISTVEHLNAALAGLGIDNIIIEVDAPEIPIMDGSASPFIYLLLDAGIEEQNVAKKFIRVKKPIRIEDGDKWAEFKPYDGFRLDFTIDFEHPAIGKDVRNYVMDFSAQAFVQQISRARTFGFMKDIEYLQSQGLALGGSLDNAIVLDDYRILNEDGLRFKDELVRHKMLDAIGDLYMCGYNIIGDFKAYKSGHGLNNKLLRALLENQEAWEFVSFEDKEEIPQGYVSPAQVFI
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: SCN4B_RAT
Sequence: MSRAGNRGNTQARWLGIGLLGLFLLPMYLSLEVSVGKATTIYAINGSAILLPCTFSSCYGFENLYFRWSYNNSETSRILIDGIVKNDKSDPKVRVKDDDRITLEGSTKEKMNNISILLSDLEFSDTGRYTCFVRNPKEKDLNNSATIFLQVVDKLEEVDNTVTLIILAVVGGVIGLLVCILLLKKLITFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPTKV
What is the function of this protein?
Modulates channel gating kinetics.  Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation.  Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.
What are the official names of this protein?
Sodium channel subunit beta-4.
What is the protein family that this protein belongs to?
Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.