PharMolix/UniProtQA huggingface dataset:
Protein: PG099_VACCC
Sequence: MENVPNVYFNPVFIEPTFKHSLLSVYKHRLIVLFEVFVVFILIYVFFRSELNMFFMPKRKIPDPIDRLRRANLACEDDKLMIYGLPWMTTQTSALSINSKPIVYKDCAKLLRSINGSQPVSLNDVLRR
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex protein OPG094, EFC protein OPG094, Protein L5.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG099 family.
Protein: AKTP2_DROWI
Sequence: MWRTLRNAQKMALINQGYRVLGEYKLLEQAELKNIYALPSYASGLHWFGVIFIHSGIYAGSMFRFSILLPDHFPEDVSLPTVIFQTEVFHPHICPVTKSLDLTPCFREWKKDQHHIWHILKYIQTIFSDPEGSVSVTETPSGDTVTLNEVHNREALNLLSKNRMEYIKRVEESIVFSRKHMYDKPPTDDAHYIVFEPYSADRHGKAMEQLKPSNWHNTVDTMATSLPAKCVARIDSARQLHEEEAKQEVPVNRKNLKEKKLTVTANSRRLQNY
What are the official names of this protein?
Protein crossbronx-like.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
Protein: KATG1_CUPPJ
Sequence: MTDKQHTRSVSESENPAIPSPTPKVSRPRRNKDWWPNQLDLSVLHTHSHLSCPLEEEFDYADQFKGLDVDALKQDLIQLMTTSQDWWPADYGHYGPLFIRMSWHAAGTYRIADGRGGGGEGQQRFAPLNSWPDNANLDKARRLLWPLKKKYGQKVSWADLLIFAGNVAYESMGFKTFGFGFGRPDVWEPEDIFWGPEDTWLGDERYSGDRELAKPLANVQMGLIYVNPEGPGGNPDPLAAARDIRETFARMAMNDEETVALIVGGHTVGKTHGAAPAAGNVGLEPEGAPIEEQGLGWKNKFGSGKGSDAITSGLEGAWTNNPTKWDNGFLENLFKYEWELTTSPAGAKQWKPKNPEANDTVPDAHGASRRHSPTMLTTDLSLRMDPIYGPIAKRFHDNPDQLEDAFAKAWFKLLHRDMGPRSRYLGPWIPEAQLWQDPIPPVDHELVSEQDIDALKRTILGSGLSVPELISTAWGAAASFRGTDKRGGANGARIRLAPQKDWESNEPSRLAKVLTALERIQNDFNGSQSGGKKVSLADLIVLGGCAAVEEAARKAGFNISVPFAPGRTDASQEQTDESIFDVLEPIGDAFRNYFRAEDPLSPETRLLDRANLLKLTAPQMTVLVGGMRMLDANHGQSRHGVFTDKPGTLSNEFFVNLLDIGTAWRPSVADKSVYEGIDRTSGKTRWTATAADLVFGAHSQLRALAEVYACDDGKERFVRDFVAAWNKVMNLDRYDLLGTRNGRRAVTSKPV
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PDRP_RICPU
Sequence: MTKLIIHLVSDSSVQTAKYAANSALAQFTSVKPKLYHWPMIRNLELLNEVLSKIEYKHGIVLYTIADQELRKTLTKFCYELKIPCISVIGKIIKEMSVFSGIEIEKEQNYNNYKFDKTYFDTLNAIDYAIRHDDGQMLNELSEADIILIGPSRTSKTPTSVFLAYNGLKAANIPYVYNCPFPDFIEKDIDQLVVGLVINPNRLIEIREARLNLLQINENKSYTDFNIVQKECLEVRKICDQRNWPVIDVSTRSIEETAALIMRIYYNRKNKYNK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RS14Z_UREU1
Sequence: MAKKSLIAKQKKHQKFAVREYTRCVRCGRPHAVNRKFGVCRLCFRDLAYAGAIPGIKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RL27_BACC0
Sequence: MLRLDLQFFASKKGVGSTKNGRDSQSKRLGAKRADGQTVSGGSILYRQRGTKIYPGVNVGRGGDDTLYAKVDGVVRFERLGRDRKQVSVYPVAQEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RNPH_NITEC
Sequence: MPRYNHRTLAQMRPIRITRHYIRHAEGSVLIEYGETKVICTASVIEKVPPFLKGAGQGWLTAEYGMLPRSTGERMQREAAKGKQSGRTMEIQRLIGRALRSVLDLKKLGERTIQIDCDVIQADGGTRTASITGAFVALCDAVGYLRAEKIISENPIKDHVAAVSVGILKGQPLLDLDYAEDSSCDTDLNVVMTGNLGLVEVQGTAEKVVFSRQELDVMLDMAQQGLQELFDLQRKTLETAAS
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: S15A5_HUMAN
Sequence: MSVTGFTITDEKVHLYHSIEKEKTVRHIGDLCSSHSVKKIQVGICLLLVELCERFTFFEVVCNMIPFCTIKLGYHNCQAAILNLCFIGTSILTPVFVRWLTDVYLGRNKLVYICLFLHFLGTALLSVVAFPLEDFYLGTYHAVNNIPKTEQHRLFYVALLTICLGIGGVRAIVCPLGAFGLQEYGSQKTMSFFNWFYWLMNLNATIVFLGISYIQHSQAWALVLLIPFMSMLMAVITLHMIYYNLIYQSEKRCSLLTGVGVLVSALKTCHPQYCHLGRDVTSQLDHAKEKNGGCYSELHVEDTTFFLTLLPLFIFQLLYRMCIMQIPSGYYLQTMNSNLNLDGFLLPIAVMNAISSLPLLILAPFLEYFSTCLFPSKRVGSFLSTCIIAGNLFAALSVMIAGFFEIHRKHFPAVEQPLSGKVLTVSSMPCFYLILQYVLLGVAETLVNPALSVISYRFVPSNVRGTSMNFLTLFNGFGCFTGALLVKLVYLISDGNWFPNTLNKGNLESFFFFLASLTLLNVLGFCSVSQRYCNLNHFNAQNIRGSNLEETLLLHEKSLKFYGSIQEFSSSIDLWETAL
What is the function of this protein?
Proton oligopeptide cotransporter.
What are the official names of this protein?
Solute carrier family 15 member 5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS17_ALBFT
Sequence: MTEAKKSLKRTLVGKVVSDKRAKTVTVLIERRVKHELYGKIVGKSSKYHAHDETGEYKLGDIIEITESRPISKTKNWVATRLVQKAAVV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y2004_NITHX
Sequence: MITSAAYVGAAVAEIAGCFAFWAWLRLGKSVWWLAPGMVSLALFAYLLTLVDSEAAGRAYAAYGGVYIIASLGWLWSVEGLRPDRWDLTGAAICLLGAAIILFGPRQI
What are the official names of this protein?
UPF0060 membrane protein Nham_2004.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASNS_MESAU
Sequence: MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVKKYPYLWLCYNGEIYNHKALQQRFEFEYQTNVDGEIILHLYDKGGIEQTICMLDGVFAFILLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVSLKHSTTPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCRDEPLHALYDSVEKLFPGFELETVKSNLRILFDNAVRKRLMTDRRIVCLLSGGLDSSLVASSLLKQLKEAQVQYPLQTFAIGMEDSPDLLAARKVANYIGSEHHEVLFNSEEGIQALDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVVIFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLKELYLFDVLRADRTTAAHGLELRVPFLDHRFSSYYLSLPPEMRVPKNGIEKHLLRETFEDSNLLPKEILWRPKEAFSDGITSVKNSWFKILQDYVEHQVDDAMMATAAQKFPFNTPKTKEGYFYRQIFEHHYPGRADWLTHYWMPKWINATDPSARTLTHYKSAAKA
What are the official names of this protein?
Asparagine synthetase [glutamine-hydrolyzing], Glutamine-dependent asparagine synthetase.
Protein: POLR_DROME
Sequence: FERKNFSDGLVPQRKFIHIGTTSTNNEPRIPLHNLMTTRPSVDIFPEDQYEPNAAATLSRVPCTVCGRSFNSKRGLGVHMRSRHPDELDEERRRVDIKARWSDEEKWMMARKEVELTANGCKHINKQLAVYFANRSVEAIKKLRQRGDYKEKIEQIRGQSALAPEVANLTIRRRPSRSEQDHQVTTSETTPITPFEQSNREILRTLRGYSPVECHSKWRAQELQTIIDRAHLEGKETTLQCLSLYLLGIFPAQGVRHTLTRPPRRPRNRRESRRQQYAVVQRNWDKHKGRCIKSLLNGTDESVMPSQEIMVPYWREVMTQPSPSSCSGEVIQMDHSLERVWSAITEQDLRASRVSLSSSPGPDGITPKSAREVPSGIMLRIMNLILWCGNLPHSIRLARTVFIPKTVTAKRPQDFRPISVPSVLVRQLNAILATRLNSSINWDPRQRGFLPTDGCADNATIVDLVLRHSHKHFRSCYIANLDVSKAFDSLSHASIYDTLRAYGAPKGFVDYVQNTYEGGGTSLNGDGWSSEEFVPARGVKQGDPLSPILFNLVMDRLLRTLPSEIGAKVGNAITNAAAFADDLVLFAETRMGLQVLLDKTLDFLSIVGLKLNADKCFTVGIKGQPKQKCTVLEAQSFYVGSSEIPSLKRTDEWKYLGINFTATGRVRCNPAEDIGPKLQRLTKAPLKPQQRLFALRTVLIPQLYHKLALGSVAIGVLRKTDKLIRYYVRRWLNLPLDVPIAFVHAPPKSGGLGIPSLRWVAPMLRLRRLSNIKWPHLTQNEVASSFLEAEKQRARDRLLAEQNELLSRPAIEKYWANKLYLSVDGSGLREGGHYGPQHGWVSQPTRLLTGKEYMDGIRLRINALPTKSRTTRGRHELERQCRAGCDAPETTNHIMQKCYRSHGRRVARHNCVVNRIKRGLEERGCVVIVEPSLQCESGLNKPDLVALRQNHIDVIDTQIVTDGHSMDDAHQRKINRYDRPDIRTELRRRFEAAGDIEFHSATLNWRGIWSGQSVKRLIAKGLLSKYDSHIISVQVMRGSLGCFKQFMYLSGFSRDWT
What are the official names of this protein?
Retrovirus-related Pol polyprotein from type-2 retrotransposable element R2DM, Retrovirus-related Pol polyprotein from type II retrotransposable element R2DM.
Protein: PURR_ECO27
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: EI3G2_DROER
Sequence: MKAFNTSWADEVEADYVDGLPPSNEYIEGDYKYVTEYKFNDDGKKVKVVRTFKIEKQIVPKAVARRRSWVKFGDSLLDKPGPNSQTTMASEEIFMQFIGSKEFDQTHETQLDPGKNIAKCRICNGEHWSVNCPYKGTSMDSKTMMETKANAAAAAAVSDPSKMGKYVPPFMKDGGGGSGGKNWGRGRDRDDSSAVRISNLSESMTEADLEELVKKIGPHTKMYLAREKNTGLCKGFAYVHFKFRQDAAAAIEVLNGHGYDHLILCVEWSKPQP
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G-2, Eukaryotic translation initiation factor 3 RNA-binding subunit 2, eIF-3 RNA-binding subunit 2, Eukaryotic translation initiation factor 3 subunit 4-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_BARHE
Sequence: MINFQLIDGEALLARLQPTLGGIKGKLTPNMDMQKVTWFRTGGLAELFYQPADEVDLAFFLQNLPESIPVTIVGIGSNLLVRDGGIPGVVIRLSAKGFGQVQQVSPTGFLVGAATADKHLAAAALEAEIAGFHFYHGIPGGLGGALKMNAGANGVETAARVVEVYALDRRGQCHTLSLADMHYSYRHCAVPEDFIFTAALLEGKPGNKGDIRAAMDEVALHRESVQPVREKTGGSTFRNPKDISAWRVIDEAGCRGLQIGGAQMSEMHCNFMINTGQATAYDLEALGETVRARVFAYSSHLLQWEIQRIGQFEQGRIVSSFDPFN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POTA_LATSS
Sequence: MQQPMVEFKNVIKKYDDNQILKGIDMALEKGKFYTLLGPSGCGKTTILRIIAGFTNASSGDVLFEGKRMNDLPANKRQVNTVFQDYALFPHLNVFDNVAFGLNLRKVKKSDVEKKVIEALKLVRLGGYEHREISELSGGQQQRVAIARALANEPKVLLLDEPLSALDMKLRKAMQYELRDLQQRLGITFLFVTHDQEEALAMSDEIFVMNEGNVLQSGTPVDIYDEPINHFVADFIGESNILPGKMVADYQVEIVGKVFECADAGMKPNEAVEIVLRPEDLDIVAVNQGQLVVTVDTQLFRGDYYEITAYDDDRNRWLIHSTNPAKDGQQVGLFFEPEDVHVMRFGESEEDFDARLESYEEED
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSBN_HUPLU
Sequence: METATLVAIFISCLLVSFTGYALYTAFGQPSRELRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYI_LIMRJ
Sequence: MRVKDTLNLGRTKFPMRGKLPVTEAQREQLWEENKVYELRQKLNEGKPTFVLHDGPPYANGNIHIGHAMNKISKDFIVRYKSMSGYRAPYVPGWDTHGLPIEHQLTKSGYDRKKMSLTEFRDLCREYALKQVDKQRTDFKRLGVSGEWDHPYLTLDKEFEAAQIRVFGEFAKKGLLYQAKKPVYWSWSSESALAEAEVEYHDVVAKTAFFVEQIKDGKGRLDNDTYLVVWTTTPWTVPASEAVAVNPKFDYSVVNPANDDRKFVVATDLLEKLAEKLGWEDYEVVDHLMGQELEGMTTQHPYLDRDLLVGLADYVTADAGTGLVHTAPGYGDDDYNFGKKYDLPIFAPINDQGVLTKENGEGFEGVFYQDADDVSLQKLEENNALLLQEPLQHSYPFDWRTKQPIIFRATDQWFVSIEKMRQNILDALEDVKYHPEWGKVRLRNMIKDRGDWVISRQRVWGVPLPIFYAEDGTPIMEEETINHVAELFAKYGSNVWFEREAKDLLPEGYTNEHSPNGKFTKETDIMDVWFDSGSSHQGVLAERDYLTYPADLYLEGSDQYRGWFNSSLITSVVCSGHAPYKEIVSQGFTLDKRGNKMSKSQGNVIDPNKVVQQMGAEIIRLWVMSADTSADVRVSMGTFQQISEAYRKLRNTFRFLLANTSDFNPEENTVSYEKLQSVDKYMLVKLNHFLKTMREDFDNYDFLDAYKVLINFVNNDLSAFYMNIAKDVLYIEAENSEVRRSMQTVFYDILLTLVKLLTPILPHTTEEVWSYMNEPEDFVQLTEIPDPRTFAGEEELLSKWDDFMEVRSHVLKSLEEARNAKLIGKSLEAQVDLYLTDDQKQLLDSLNENIQLLLGVSALHVHPADEAPADADQYNDGVAVKVTTANGETCARCRMVKEDVGSDPAYPELCARCAAIVRENFPETAEDGLEE
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_SHELP
Sequence: MKQLESSIRIEVKTDYIEEQSSPEEERYLFSYTITIINLGDEAVTLKSRMWCITDANGHESKVEGAGVVGETPTIKPNTAYQYTSGTVCETPFAVMQGYYVMVTEQGETFKAPIAPFRLAAPGLLH
What are the official names of this protein?
Protein ApaG.
Protein: INSC_SHIFL
Sequence: MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLLGKKTMENELLKEAVEYGRAKKWIAHAPLLPGDGE
What is the function of this protein?
Involved in the transposition of the insertion sequence IS2.
What are the official names of this protein?
Transposase InsC for insertion element IS2.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: PEPA_ASPCL
Sequence: MVVFSKVTAAVFGLATIASAAPAPPTRKGFTVQQQARPAQKKQVNLPAMYAHALTKFGGSVPESVKVAASKGSAVTTPEAGDVEYLTPVNVGGTVMNLDFDTGSADLWVFSGELPASETSGHSVYKPGRTASKLPGGSWQISYGDGSSASGDVYKDTVVVGGVTAHGQAVEAAAQISSQFLQDKNNDGLLGLAFSSLNTVQPQPQTTFFDTVKSSLDRPLFAVTLKHNAPGSFDFGYIDHSKYTGEIAYTDVDNSQGFWSFTADGYSIGGGQSSGSSISGIADTGTTLLLLDDNVVSDFYQHVEGAQNSDEYGGYVFPCSAKVPSFTTIIGGYKAVTPGKLINYGPVTDGSSTCYGGIQSSGGVGQNIFGDIFLKSQFVVFDSEGPRLGFAAQA
What is the function of this protein?
Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates.  The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site.  Shows a broad primary substrate specificity.  Favors hydrophobic residues at the P1 and P1' positions, but also accepts a lysine residue in the P1 position, leading to the activation of trypsinogen and chymotrypsinogen A.
What are the official names of this protein?
Aspergillopepsin-1, Aspartic protease pepA, Aspergillopepsin I, Aspergillopeptidase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NEC1_HUMAN
Sequence: MERRAWSLQCTAFVLFCAWCALNSAKAKRQFVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKLNIPYENFYEALEKLNKPSQLKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNEEN
What is the function of this protein?
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues.  Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
What are the official names of this protein?
Neuroendocrine convertase 1, NEC 1, Prohormone convertase 1, Proprotein convertase 1, PC1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules.
Protein: TRMFO_STRGC
Sequence: MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKSTPQHKTADFAELVCSNSLRGDALTNAVGLLKEEMRRLDSVILKSAEATRVPAGGALAVDREGFSQMVTELVTNHPLIEVIREEITEIPNDDITVIATGPLTSDALAEKIHALNGGNGFYFYDAAAPIIDVNTIDMTKIYLKSRYDKGEAAYLNAPMTKQEFMDFHDALVNAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYQGPRDGEYKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQTFRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEEALVFPETTAIGSLPHYVTHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEKIAERALQDLAPYLDK
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBB1_ECOLX
Sequence: MILRGCTMALERYNVSQPKRQAERGENTADPALAAGRACSTAELVARRLGIAAVQPVYRFLDTWWRKGCWSGEITRLTAVRSACGADAARGGVLVRRGRAADGHYSVSCRRGVCAQLPRTGWPFELLRLAMEGNSRGAPAGGTCTVLP
What is the function of this protein?
This protein is essential to promote the specific transfer of the plasmid in the presence of conjugative plasmids.
What are the official names of this protein?
Mobilization protein MobB, Protein C.
Protein: YQGF_DEHM1
Sequence: MGDKWIGVALSDPLRILASPLVILRRDDDAKTVENIEALVKTHQPDLLVIGLPVSLNGTIGPQAEKVKAFSGLLSQSLNTEIIFRDERFSTDEARRKMNDSGKNNKTVRDDAAAAAVILQDYLDETNPPCFQP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_THISH
Sequence: MSAENRIRALRALGQSIWYDYIRRDLLDSGELARLIREDGLGGLTSNPAIFDKAIAGTDLYRTAIRDALRADPGLNDEALFFRLAIEDLQRAADVFLPLYRETGGADGFVSLEVSPDLAHDAEATVREARALFARMDRPNAMIKVPGTRAGVEALETLIADGVNVNVTLLFSVARYAQVLEAWMRGMEARLERGEALETVTSVASFFVSRVDSVLDPLLEERIQEGRPAEHLRGRLAIANARLAYAHFRDQRGGARHTRLTAAGAHPQRLLWASTGTKNPDYSDVLYVDSLIGEHTVNTLPPATYRAFLDHGSVAETLAEGVETARAQVAALADLGIDLESITDRLESEGIEAFQKAFRHLLGVLAEARQGKR
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_FRATH
Sequence: MANFVLKAEKREDLGTGASRRLRRAGKIPAVIYGGEKEAVSVLLDHDKVLHSTEDKEFFSSEITLDIDGKQEKVIIKALQRHPYKVKLIHADFMRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: RL17_BRUSI
Sequence: MRHGNGYRKLNRTASHRKAMFANMAASLIEHEQIVTTLPKAKEIRPIVEKLVTLGKRGDLHARRQAISAIRDVKLVAKLFDTLAARYATRNGGYIRIMKAGFRAGDNAPLAVVEFVERDVDAKGKADRARVEAEAAAEADAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SIZ2_YEAST
Sequence: MASVMSNNNNNNNNNNASYMFTNPLSNTGGGLINEIKDAINEMEQLKVLELKQICKSLDLSITGKKAVLQDRIKQFLRKSCDIGHIDPWRPKAIKILIAKVRINSSLPKYSTLWETLKTGAFKHPVASGQLPVTALQSTALPPYSQQQALAYSFTSPFYKPIVQIPDANKKLKQSAGRGCTKMKFKVSKSNHDLLKSNKSYKLYLFSGFSIPFIYETVGHEAIDFPYPCELVFNGTKLEDNVKGLKKQNGTGNPANLTPYLKVPTEMNHLDLHYLNIDKEYSISCFIVEVFSPEALLGKILKRPKIIKQATTAYIKRTLNEQDDDDIITTSTVLSLQCPISCTRMKYPAKTDQCKHIQCFDALWFLHSQSQVPTWQCPICQHPIKFDQLKISEFVDNIIQNCNEDVEQVEISVDGSWKPIHNSSAVITDTVNQNHSVKNENQGTVKQEQDYDSRNAFDTNLRNGSNHNEPEIISLDSSDDEAFIPASKSFPTHVNPRNDQLRADIFPSESEGSSDYNPNHTSTPKGSPTMDQDNYQDAFQMRSFLNQGATTNINDTPTNNSSINSFVTATNGDSRIFYNRGPSTPLLPAVLQNLTNQTEAQRNPYGPNYNTTAQDRNLLGIEGDLPPIPPVDPNSEAETELPTRTTSAAHLPPYIHVSTSGHGDDGKIRKRRHSNVSIYIPKNPYATLMKRRPQANHAIMNKTLAQTNDFNTSAQDNSEVVDLTSD
What is the function of this protein?
May act as an E3 ligase mediating SUMO/Smt3 attachment to septins.  May be involved in chromosome maintenance.
What are the official names of this protein?
E3 SUMO-protein ligase SIZ2, E3 SUMO-protein transferase SIZ2, SAP and Miz-finger domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the PIAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCH1_VIBCH
Sequence: MSGLSESAKLVKDALERRGLETPMQPNLATPAEKKEKIEQHMREILNLLGLDLTDDSLEETPQRIAKMYVDEIFSGLDYANFPKITVIENKMKVSEMVKVKDITLTSTCEHHLVTIDGTAAVAYIPRGKIIGLSKINRIVRFFAQRPQVQERMTQQILVALQTLLESDDVAVTIDATHYCVKSRGVMDATSVTTTTALGGIFKSNPATRAEFLHGLR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.