PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_TROW8
Sequence: MNGIKHIFITGGVVSSIGKGLTAASLGSLLTMRGLKVFIKKLDPYLNVDPGTMNPLQHGEVFITEDGAETDLDVGHYERFLDVDLDRTANVTTGQVYSKVITLERTGRYLGETVQVIPHITDEIKRRIRLAPDDIDVIITEIGGTVGDIESQPFIEAARQIRREVGRENCCFIHVSLVPFLESAGEQKTKPTQHSVAILRAAGIQPDALVLRSDKPISSANQKKIALMCDVSAVVNAVTVPNIYEIPCVLNQHGLDKFVIKHLDLEAGEIDWSYWDDVLDAIENNRSEIEIAIIGKYTGLPDAYISVIEALRAGGFESKTKVNIKWVDSDDENLEDQLENINGACIPGGFGIRGIEGLIKAIRICREREIPTLGICLGMQCMVIEYARHVVGMHGASSTEFTDDTQWPVVTTMLEQRDILIDDQFGGTMRLGSYRAVLSVGSLAASLYGTTDIHERHRHRYEVNNGYAQRLVERGLIVSGRNTEQDLIEFIELDRKDHPFYIGTQAHPECKSRPKRPHPLFKGLVAAALARKEIAEFNSGKTVLQ
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RSXC_SALG2
Sequence: MLKLFSAFRKDKIWDFDGGIHPPEMKTQSNGTPLRQVPLAPRFVIPLKQHIGAEGELCVSVGDRVLRGQALTRGRGRMLPVHAPTSGTVIAIAPHSTAHPSALAELSVIIDADGEDRWIEREGWSDYRAHSREALIERIHQYGVAGLGGAGFPTGVKLQGGGDKITTLIINAAECEPYITADDRLMQDCAAQIVEGIRILAHILQPREVLIGIEDNKPQAISMLRAVLADAHDISLRVIPTKYPSGGAKQLTQILTGKQVPHGGRSSDIGVLMQNVGTAYAVKRAVVDGEPITERVVTLTGEAVSRPGNVWARLGTPVRHLLNDAGFCPSADQMVIMGGPLMGFTLPWLDVPVVKITNCLLAPSVTEMGAPQEEKSCIRCSACADACPADLLPQQLYWFSKGQQHDKATAHHIADCIECGACAWVCPSNIPLVQYFRQEKAEINAIRLEEKRAAEAKARFEARQARLEREKAARLARHKSAAVQPAAKDQDAIAAALARVKEKQAQATQPVVIQAGSLPDNSAVIEAREARKAQARAKQAAHPVADSAISGGAPRKAAVEAAIARAKARKQEQQAGSEPAEPVDPRKAAVEAAIARAKARKQEQQAGSEPAEPVDPRKAAVEAAIARAKARKQEQQAGSEPAEPADPRKAAVAAAIARVQAKKAAQQQVVNED
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rsx electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DTD_CITBB
Sequence: MKAVIQRVKEAKVSVEGRVVGEIGKGVLVLLGVEIGDGCAQADWMAEKIVNLRIFADNEGKMNLALPEVKGEMLAVSQFTLAGNCSKGRRPSFDTAAAPEEANRLYSYFMGQVWERGVPVQSGIFQADMEVSLVNDGPVTFILETPPKR
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y803_STAAR
Sequence: MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIPTTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKLAAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAWVGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFEDGQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein SAR0803.
Protein: PNX33_SCOMU
Sequence: MKAFIAILSIAIVLLLIVSIKETSAKDCKQECVKRYTKGDLTNFLKAEYEPKNRGGICYCEFTCHVKFYIYLKHEMD
What are the official names of this protein?
Putative neurotoxin 1, Putative neurotoxin 3.
What is the protein family that this protein belongs to?
Belongs to the scolopendra neurotoxin 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYK_HALSA
Sequence: MHPDDDPYADDGSGRLFWADAAADRVLDGDPEEPIVIKGGISPSGVPHLGNMNEIMRGYFVAAVLRERGHEVRQVFTSDDRDPLRGLPRKLADLDGEVVALGDVNAGALGQNLGAPYTEIPDPFGCCDSYGAHFSNLIQSSADRLGVDVEMVSNTETYANGGFEEVTRYLLEHVTAARDVLGEYQDKVDEEYVPFNPICEACGKVTETVTDVDADAGTVEYVCTDMDAGDQTIEGCGHEGTATLREGKLPWRFEWPAQWRTLGVDYEPFGKDHAEGSWPSGTDISRNVLGDEPPTPMVYEWFTLDGEPFSSSAGHVILVQDVLALLELPVVRYFFSKDPRRARDFSIEHLDQLVDEFDRMERVYFGEAADASEDERERAARVYPLLVDDIDADRVRIPFTFAAVLGMTEDSALREEIARREGHIPADADADTVADALTRVERAREWARRTNNEFNYRLARAEIPAHDFDDATAAALDELAAFLDDEDPDGEALQGEIYEAAKRHDIDIGAFFAAGYRLFFDEDQGPKLGPFLAKLDREFVVTRLRREG
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NB5R3_PIG
Sequence: STPAITLENPDIKYPLRLIDKEVVNHDTRRFRFALPSPEHILGLPVGQHIYLSARIDGNLVIRPYTPVSSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMKIGDTIEFRGPNGLLVYQGKGKFAIRPDKKSSPVIKTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNEHSARFKLWYTVDRAPEAWDYSQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLERVGHPKERCFAF
What is the function of this protein?
Catalyzes the reduction of two molecules of cytochrome b5 using NADH as the electron donor.
What are the official names of this protein?
NADH-cytochrome b5 reductase 3, B5R, Cytochrome b5 reductase, Diaphorase-1.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm. Note=The enzyme exists in two forms, a membrane-bound form on the cytoplasmic side of the endoplasmic reticulum and also on the mitochondrial outer membrane and in soluble form in erythrocytes. NADH-cytochrome b5 reductase 3 membrane-bound form: Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Mitochondrion outer membrane; Lipid-anchor; Cytoplasmic side. NADH- cytochrome b5 reductase 3 soluble form: Cytoplasm.
Protein: FOLD_METBF
Sequence: MLDEGYESRIIDGKVLAKKIEDEVRSGVEALVSGRGITPGLATVLVGDDPASKMYVRLKHRACERVGIQAEDHFLPAETSQEELISLINTLNKDQNVHGILLQLPLPKHLFPQEAMEAIAPEKDADGFHPYNMGKLMIGDEGLVPCTPHGVIRALEEYNVPVKGKNVVIVGHSNVVGKPLAAMFLNRNATVSVCHVFTDDLKKYTLDADILVVATGVKHLIKADMVKEGAVIFDVGITKEKDGVYGDVDFENVIKKAALITPVPGGVGPLTVAMLMKHVLGCAETNY
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RPOZ_WOLWR
Sequence: MAESIVEKCIERVSNRFKLVLLASQRTHDLNTGASNPIQAAKFKGHKNTIVSLHEIAGKQVDTHELFSLLVGRCKEYMKGNMNNVYSSNTSKLANLLNFSDNTDLDASQESQDYEVDGEIDDEINDQDGDEEVSV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: KCY_ALISL
Sequence: MTIHSPVVTVDGPSGAGKGTLCMLLAEKLGYNLLDSGAIYRVLALAAIHHGVDLGSEEGLVPLAANLDVQFKAEGDLVKVILEGEDVSSELRKEETGMAASKVAALPQVREALLRRQRAFASAPGLVADGRDMGTVVFTGAEVKIFLDASAEERANRRMKQLQQKGLNVRFDRLLSEIQERDDRDRNRAVAPLRPAEDALVLDSTSMNIDEVVAQALTFIESKL
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 122R_IIV3
Sequence: MSHVSVIAARLLVWVGILLCLGVPQLWANPIYLYEPSANKSTRAPQVLGVPPEVYAFTVSCKACWLP
What are the official names of this protein?
Uncharacterized protein 122R.
Protein: PEK13_ARATH
Sequence: MSDSPTSSPPAPSADSAPPPDTSSDGSAAPPPTDSAPPPSPPADSSPPPALPSLPPAVFSPPPTVSSPPPPPLDSSPPPPPDLTPPPSSPPPPDAPPPIPIVFPPPIDSPPPESTNSPPPPEVFEPPPPPADEDESPPAPPPPEQLPPPASSPQGGPKKPKKHHPGPATSPPAPSAPATSPPAPPNAPPRNSSHALPPKSTAAGGPLTSPSRGVPSSGNSVPPPANSGGGYQGKTMAGFAIAGFAVIALMAVVFLVRRKKKRNIDAYSDSQYLPPSNFSIKSDGFLYGQNPTKGYSGPGGYNSQQQSNSGNSFGSQRGGGGYTRSGSAPDSAVMGSGQTHFTYEELTDITEGFSKHNILGEGGFGCVYKGKLNDGKLVAVKQLKVGSGQGDREFKAEVEIISRVHHRHLVSLVGYCIADSERLLIYEYVPNQTLEHHLHGKGRPVLEWARRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEFEAQVADFGLAKLNDSTQTHVSTRVMGTFGYLAPEYAQSGKLTDRSDVFSFGVVLLELITGRKPVDQYQPLGEESLVEWARPLLHKAIETGDFSELVDRRLEKHYVENEVFRMIETAAACVRHSGPKRPRMVQVVRALDSEGDMGDISNGNKVGQSSAYDSGQYNNDTMKFRKMAFGFDDSSDSGMYSGDYSVQDSRKGSNGASSEFTRNETENRNFNNRRY
What is the function of this protein?
Regulates negatively root hairs elongation.
What are the official names of this protein?
Proline-rich receptor-like protein kinase PERK13, Proline-rich extensin-like receptor kinase 13, AtPERK13, Protein ROOT HAIR SPECIFIC 10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: VKT2O_HETCR
Sequence: GSICLEPKVVGPCKARIRRFYFDSETGKCTPFIYGGCGGNGNNFETLHACRAICRA
What is the function of this protein?
This recombinant serine protease inhibitor inhibits both trypsin (Ki=21 nM) and chymotrypsin (Ki=500 nM) (Ref. 3).  It possesses anti-inflammatory activity in vitro (Ref. 3).  It inhibits macrophage LPS-induced nitric oxide synthesis, and blocks histamine influence on intracellular calcium concentration in murine bone marrow-derived macrophages, which can indicate inhibition of H1-histamine receptor (HRH1) (Ref. 3).  In vitro, it shows cytoprotective activity in the oxidative stress agent 6-hydroxydopamine (6-OHDA)-induced neurotoxicity model (PubMed:33802055).  In this model, it decreases reactive oxygen species (ROS) levels, and increases cell viability in a correlated manner (PubMed:33802055).  It is possible that the observed effect is due to the ability of this peptides to act as free-radical scavenger (PubMed:33802055).  In vivo, it shows analgesic activity, since it increases hot plate and tail flick withdrawal latencies, when using a mice thermal pain stimulation model (PubMed:25937220).
What are the official names of this protein?
PI-stichotoxin-Hcr2o, PI-SHTX-Hcr2o, GS-polypeptide 1, GSP1, Kunitz-type serine protease inhibitor HCGS1.20.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: THII_STAA9
Sequence: MKYDHLLVRYGELTLKGSNRKKFVNQLRNNVNKSLKGLDGFVVKGKRDRMYIELEDHADINEITYRLSKIFGIKSISPVLKVEKTIEAMSAAAIKFAQQFEENSTFKIDVKRADKNFPMDTYELQRELGGTVLKQIENVSVNVKRPDHEIRVEVRLDAIYMYEEVVPGSGGLPVGTGGKTLLMLSGGIDSPVAGMEVMRRGVTIEAIHFHSPPFTSDQAKEKVIELTRILAERVGPIKLHIVPFTELQKRVNKVVHPRYTMTSTRRMMMRVADKLVHQIGALAIVNGENLGQVASQTLHSMYAINNVTSTPVLRPLLTYDKEEIIIKSKEIGTFETSIQPFEDCCTIFTPKNPVTEPNFEKVVQYESVFDFEEMINRAVENIETLEITSDYKTIKEQQTNQLINDFL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLIS1_MOUSE
Sequence: MHCEVAEALSDKRPKEAPGAPGQGRGPVSLGAHMAFRIAVSGGGCGDGNPLDLLPRLPVPPPRAHDLLRPRSPRDYGVSKTGSGKVNGSYGHSSEKSLLDLDLAEGPSPSCHQGLFLPAGTPPPRGHPPVCEKLLHFPHPNRSPRPQATFVNGSLPAAQHIKQEALPDYQAMVSAHTPLPTHCRAPSSMGLPSDLDFPDRGLTNPAPSCYLLGNEPISDLGPQPEAHLPEGSLKRCCLLGLPPTSSASSSPCASSDINPVIHSSQTALVSCVNGLRSPPLPGDLGGPPKRSRPGPASSDGQEGSLQLEACRKSGFLKQEPMDEFSELFAPHHQGLPPPYPLPQLPTGPGLGGLGLGLAGRMVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHTGADPEADVLSECLSLQQLQASTLLPASRGKGSQTLSQELLPGVYPGSVTPQNGLASGILSPSHDVPSRHHPLEVPTGSHHHLSPLPTAESTRDGLGPSLLSPMVSPLKGLGPPPLPPASQSQSPGGQSFSTVPSKPTYPSFQSPPPLPSPQGYQGSFHSIQNCFPYADCYRATEPAASRDGLVGDAHGFNPLRPSTYSSLSTPLSAPGYETLAETPCPPALQPQPAEDLVPSGPEDCGFFPNGAFDHCLSHIPSIYTDT
What is the function of this protein?
Acts as both a repressor and activator of transcription (PubMed:12042312, PubMed:12385751, PubMed:21654807).  Binds to the consensus sequence 5'-GACCACCCAC-3' (PubMed:12042312).  By controlling the expression of genes involved in cell differentiation inhibits the lineage commitment of multipotent cells (PubMed:21654807, PubMed:30544251).  Prevents, for instance, the differentiation of multipotent mesenchymal cells into adipocyte and osteoblast (PubMed:30544251).
What are the official names of this protein?
Zinc finger protein GLIS1, GLI-similar 1, Gli homologous protein 1, GliH1.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
Protein: AMY2_DROAN
Sequence: MFLAKSIVCLALLAVANAQFNTNYASGRSGMVHLFEWKWDDIAAECENFLGPYGYAGVQVSPVNENAVKDSRPWWERYQPISYKLVTRSGNEEQFASMVRRCNNVGVRIYVDVVFNHMAADGGTYGTGGSTASPSSKSYPGVPFSSLDFNPTCAISNYNDANQVRNCELVGLRDLNQGNSYVQEKIVEFLNHLIDLGVAGFRVDAAKHMWPADLGVIYGSLKNLNTDHGFESGAKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKAFRGKNQLQYLVNWGVSWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQGPPTTDGQNIASPSFNSDNSCSGGWVCEHRWKQIYNMVGFRNAVGSDAIQNWWDNGSNQIAFSRGSKGFVAFNNDNYDLNSSVQTGLPAGTYCDVISGSKSGSSCTGKTVTVGSDGRANISIGSSEDDGVLAIHVNAKL
What are the official names of this protein?
Alpha-amylase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: LPLA_YERPE
Sequence: MSSLRLLISDSYDPWFNLAVEECIFRQMSPNQRVLFLWRNADTVVIGRAQNPWKECNTRRMEQDGVKLARRSSGGGAVFHDLGNTCFTFMAGKPGYDKTISTQIILNALASLGIQATASGRNDLVVINGEDERKVSGSAYKETKDRGFHHGTLLLNADLSRLADYLNPDPKKLQAKGITSVRSRVTNLVELLPGIDHGKIRTAIEQAFFAYYDEQVSAEVISPQSLPNLPGFTEQFAKQSSWEWNFGQAPAFSHVVDTRFIWGGIELHFDVLHGAIDRCQIFTDSLNPTPLEALAQRLQGAAYRPDAIDKICQHWIDDFPELQTELQQACHWLVEVLR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_XYLFM
Sequence: MTTPTPLRSVTVNTPPPYTIAIGPGLLHDPPRLAATIRGRHALILSDSEVAPRYAAQLHETLLRARPDLHLNVFTLPAGETSKSLENFGAAIAQLATLGATRDACLFALGGGVIGDLTGFTAACWMRGIDYVQVPTTLLAMVDSSVGGKTAVDIPQGKNMVGAFHPPRAVIADTDTLATLPLRELRAGLSEVIKYGAIRDPVFFHWLQTTREALLARDPAALAQAIARSCEHKADIVGRDPLEKGERVLLNLGHTFGHAIETTQGYSTPGSNNLNHGEAVAVGMVLAARLSNTLGLAPAEDTETLKNLLDAYGLPTVLPSGLKPETLLERMRLDKKNIAGRLRLVLWRGIGHAEAVPDVDEAAVRQILAN
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR2_METBU
Sequence: MNVLIIGGGGRENAIADAIARSERNPALFAVMAKKNPGIAALCEDFLLAKETDVEKVVGYAREKGIEMVFIGPEAPLAVGLADALEDAGIGAVGPRKNVARIEFDKAWARNFMKDNDIEGSPAFKVFSDKEGLQEYIEELGSVAIKPAGLTGGKGVKVMGDQLPDTGAAYDYAVSLLDGDNVVVEENLVGEEFTVQAFVDGKNLAFTPCVQDHKRAFENDFGPNTGGMGSYSDSDGLLPFVTIDDLYHAREIMKATITALGATETPFKGMLYGQFILTKNGPKVIEFNARFGDPEAMNVLPLLKTDMIDVMSAVVNGTLDELDVEFLKRATVCKYAVPAGYPDEPSKDKEVVVGNIGDALLFYSSVYEKDGKVYTTSSRAVAVVGVANSITDAEVIAQNALENITGDLHFRRDIGTPELVQRRVTHMEQIRR
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: CRCB1_HALMA
Sequence: MADTHPLVTVETIVLVGLGGFAGSNLRYFVGLFFPGLQGTLLVNVCGSFALGVLVYEGLQVGALASETKLAASTGFISSFTTYSTFAVETVLTPEWAVANVVGSYALGFAGVLVGREVVRLFAGGGQ
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPO12_PYRAE
Sequence: MTEERKLYVCMRCGRIFSKSEMEILPGIRCPYCNFKIIMKVRSPMVKRIPAI
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo12, DNA-directed RNA polymerase subunit P.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHP6_ASPFU
Sequence: MPKEKTSTRTKTKRVERKKKDPNAPKRGLSAYMFFANENRDKVREENPGISFGQVGKMLGERWKALSDSERRPYEEKAAADKKRYEDEKASYNAAQDEDEEESS
What is the function of this protein?
DNA-binding protein that induces severe bending of DNA.  Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).
What are the official names of this protein?
Non-histone chromosomal protein 6.
What is the protein family that this protein belongs to?
Belongs to the NHP6 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RECO_CUTAK
Sequence: MPTYRDQAVVLRTHKLGEADRIVSMLSREHGKIRAVARGIRRTSSKFGARLDPFNLVDLQLVQGRNLDVVAQVECLHPYSAPLRQDYSLFTAAEVMVEAADHLVPVDREPAPAQYRLLAGALRVLGQGTTDGPRPPEMVLDSYLLRSLSASGYAPDLVDCVRCGTPGPHQGFSPSLGGVVCINCQPPGTPHPHEETISYLRALLVGDWTATRDVAWSRVREGSGLVAAFVSWHMDRGLRSMPLLER
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: LSPA_ECOSE
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ERA_LISW6
Sequence: MSEPFKSGFVAIVGRPNVGKSTLLNHIIGQKIAIMSDKAQTTRNKVQGVYTTDESQIIFIDTPGIHKPKHKLGDFMVKIALNTFQEVDLIYFVIDASTGFGRGDEFIIEKLKNVQTPVFLLINKIDLISPEDLFKLIEQYRELLDFEEIIPISALQGNNVPNLLEQTNANLEIGPMYYPKDQITDHPERFIISELIREQVLQLTREEVPHSVAVVIEGIEKNPKTEKLTINATIIVERSTQKGIIIGKQGQMLKQIGMRARKEIESLLGSKVFLEIWVKVQKNWRDKEHYLHDYGFDREEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: SECA_CAMJR
Sequence: MFLNTLKAVFGTKNDREVKKYFKRVAQINALEGNYQNLSDDELKAEFAKFKEQILSGEKNENDVLNDVFAIVRETGKRTLNMRHFDVQLIGGMVLHDGKIAEMKTGEGKTLVATLPVVLNAMSGKGVHVVTVNDYLAKRDAEQMSAIYNFLGFSVGVVLSSQNSDIEHKQAYDCDITYGTNNEFGFDYLRDNMKFSKAEKVQREHNFVIVDEVDSILIDEARTPLIISGPTNRTLDGYIKANEVAKQMQKGEAVLPPAKPEGDFVVDEKNRNILITEAGIAKAEKLFGVENLYSLDNAILAHQLDQALKAHNLFEKDVHYVLRNNEVIIVDEFTGRLSEGRRFSEGLHQALEAKENVKIQEESQTLADITFQNYFRMYNKLAGMTGTAQTEATEFSQIYSLDVISIPTNIPIKRQDKDDLIYKTQNEKFKAVIEEIKKANAKGQPVLVGTASIERSEVFHNMLVKEKIPHHVLNAKNHEQEALIIQDAGKKGAVTIATNMAGRGVDIKIDDEIRALGGLYIIGTERHESRRIDNQLRGRAGRQGDPGISRFYLSLEDNLLRIFGGDRIKSIMDRLGIEEGESIESRIVTRAVENAQKKVESLHFESRKHLLEYDDVANEQRKTIYRYRNELLDENYDIRAKISQNIAEYSANVMNDYILDESGSNVNFENLKAKILYECSTQISEKDFENLSVIEMQDKLSQILENSYNEKMSRLEIKELRNIERILYLQVLDNAWREHLYQMDILKTGIGLRGYNQKDPLVEYKKESYNLFLELVNRIKFDSIKLLFSVQFNQEEVQNLENKANEENEKLLQSSVEMGASEDNLGEAEFKKVPRNAPCPCGSGKKFKECHGKSGPKQGILA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: THII_VIBPA
Sequence: MKFIVKPHPEIFVKSESVRKRFTKILECNIRNIVKSRTESVAVFNRRDHIEVTSESNEYHAEVLEILTHTPGIHHVLEVKQSEFKDLHDIYEQVLELSRPLIENKTFVVRAKRRGKHDFTSIELERYVGGGLNQAVESARVKLHNPDVTVKVEVSGDKLNQVLARHKGLGGFPLGTQEDVLSLISGGFDSGVSSYLHIKRGSKVHYCFFNLGGPAHEIGVKQVSHYLWNKYGSSAKVRFISVDFEPVVAEILEKVDDGQMGVILKRMFMRAAGMIAEKFKIEALVTGEALGQVSSQTLTNLRHIDNVTDTLILRPLINWDKEDIINLAREIGTEDFAKTMPEYCGVISKKPTVKAVKEKLEAEEAKFDFSILEKVVYEARQMDIRDIAKESEQAAPEVEQVQAVEEHAVVLDIRSPDEEDDNPLEIAGVDVKHIPFYKLGTQFGDLDQSKTYLLYCDRGVMSRLQALYLQEQGFNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.