PharMolix/UniProtQA huggingface dataset:
Protein: PYRB_STAA9
Sequence: MNHLLSMEHLSTDQIYKLIQKASQFKSGERQLPNFEGKYVANLFFENSTRTKCSFEMAELKLGLKTISFETSTSSVSKGESLYDTCKTLESIGCDLLVIRHPFNNYYEKLANINIPIANAGDGSGQHPTQSLLDLMTIYEEYGYFEGLNVLICGDIKNSRVARSNYHSLKALGANVMFNSPNAWIDDSLEAPYVNIDDVIETVDIVMLLRIQHERHGLAEETRFAADDYHQKHGLNEVRYNKLQEHAIVMHPAPVNRGVEIQSDLVEASKSRIFKQMENGVYLRMAVIDELLK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: NRA1_CAEEL
Sequence: MNQPIGIADSSRPKTNVRLTISANNLMDLDVFSKSDPICLIYEKTSGRKATTTEEITVPTWKDKQWTERGRTEVVMNNLNPQFTKTFLLPYFFEETQLLRFEIYDADSPTVGQDLSSHDFLGRFECVLAQIVSYSTLKAHLGKTGQIGAQWRNKDKNTKTGSITIYAEEDEKAEKIQFDVCGEGLDKKDFFGKSDPYLNFKRKFDDGSTHLIHRTEVKPKTLDPRWATVQINTQTLCAKDGDRPIIIECYDHDKWKKGEEPRGDAKFSRDDLIGTAQTTLNELLRGSSDAVEILLTNEKKKAKKGDKYKCSGTLKIWNSRIVIEPTFLDFISGGTQLDFAVAVDFTASNGPPKSSSSLHFMSADRPNQYELALRSVLSICQHYNSSKTFEAFGFGAKLPNQSSVSAIFPLDLQRGTSEVVGITGVMTAYRHALSNVQLYGPTNFAPIIENVARKAQNMIHDSARYQILLIITDGIISDMHATIRSIISASGLPLSIIIIGVGNEDFEKMHELDSDDALLQQDSRIAQRDIVQFVTMREFLNNGQGLYLDPDVIQENLAREVLYEVPAQLTGYMKQRGFQPRPVDDPWRRDSPPPEFDPILDGTGRRAPMLQAPPAGFQYPVYADTSIASAPPMY
What is the function of this protein?
Exhibits calcium-dependent phospholipid binding properties (By similarity).  May function in membrane trafficking.  Regulates synaptic levels of nicotinic acetylcholine receptor subunit lev-1 and unc-38 in the nerve cord (PubMed:15990870).  Involved in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine and levamisole (PubMed:15990870).  Affects directional sperm motility (PubMed:16998478).
What are the official names of this protein?
Nicotinic receptor-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: URE1_RHIME
Sequence: MSYRMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTREGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSHEIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGAYGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDPETYEVRADGELLTCEPATVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_PSEU2
Sequence: MARYIGPKCKLARREGTDLFLKSGVRAIESKCNIEAAPGIHGQRRGRQSDYGTQLREKQKVRRIYGVLERQFSGYYKEAAGKKGATGENLLQLLECRLDNVVYRMGFGSTRAESRQLVSHKSVSVNGKTVNVPSYQVRAGDVVAIREKAKNQLRIVQALDLCAQRGRVEWVEVDTEKKSGVFKNVPARSDLSADINESLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL24_COLP3
Sequence: MASKIRRDDEVIILAGKDKGKTGKVTKVLVEDGKVFVEGINLIKKHTKPVPQLQQPGGIVEKEAPLQVSNVAIVNSATGKADRVGFRIEDGKKVRFFKSNNELI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ALR_RICPU
Sequence: MSLCTVEINLSTIKNNYLLLQDVCKTSLVGAAVKANGYGLGAVQISKALIEENCRHFFVASSEEGVNLRNALGLDVNILVLNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKNRLLPCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYIISHLAISEEIDNPYNLEQLNRFKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPLTKNPVTLKAPIIHLQNLTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLINIDVTDLPPSEIFLGQEAEIIGNYCTPDKIASIIGTIGYEVLTNLGSRYKRKYIG
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ICP22_EHV4
Sequence: GSCRMSQRGAPSTSPIIPSLSPSSGGNPSPRSSQRIDSVRVPARLPGGSDHPEYGLPLSPRSLRPYLSRGPGAFCAPPWRPDVNRLAGDVNRLFRGISTSSIHVTEDSRVLRRVLLDFYAMGYTHARPTLECWQALLQLMPEQSLPLRATLRAINSEDKYEQRFLDPPSKPPKTLFGEECEVSGDESPSEEEEASGNSTISEFSPEEESASSDFESFSDEEDDSCCTGKWSSSESDSEADVPTNPPTTRARAAQKRRGRPVPKGGRPAKSARR
What are the official names of this protein?
Transcriptional regulator ICP22 homolog, Immediate-early protein IE68, ORF4.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae ICP22 family.
Protein: RLMKL_ACTP7
Sequence: MTTQITYFATAARGFEEMLKTELEQICQAECKVAQGGVHFTTTQRGAYQALLHSRLASRILLPLVTTKIFSDLDLYATIVGINWAEIFDPRDTFFVDFNGTNREIRNTQFGAMRVKDGVVDYFERKGFARPTVDKDHADIRIHVYLDRENMVVSLDLSGDALHMRGYREDTGKAPLRETLAAAIILRSGWQKGTPLVDPMCGSGTLLIEAAQMQAGIAPQLHRKHWGFNAWKGHQQAVWKEVLEQAYLQQNEEIQPLFFGFDLDHRVLAKAKQNARNAGVAHLIQWQQGDVAALKNPCPEQVGTVICNPPYGERLGTTPALIALYSVFGQRLKHQFSGWNASIFSGEPELLNCLRLRSHRQFKAKNGPLDCLQKNYQISERAVAEQQADELKFEQNAQVAPDFANRLTKNIKKIEKWAKQQGINAYRLYDADLPEYNLAVDRYDDHIVVQEYAAPKNIDEQKARQRLLDAVSATLYVTGVETNKLVLKVRQKQKGTNQYEKLANKGDYFYVTEYGAKLWVNLTDYLDTGLFLDHRLTRKMVGQMAKGKTFLNLFAYTGSATIHAALNGAKSTTTIDMSNTYLNWAEQNLELNNLPLRNNRLFQADCLQWLAECRERFELIFVDPPTFSNSKRMEDSWDVQRDHIKLMTQLKRILTADGIIVFSNNKRGFKMDFEGLAELGLQAENISHKTLPLDFERNPQIHNCWIIRHIEN
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BT3L4_HUMAN
Sequence: MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGTVIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKAPKPEDIDEEDDDVPDLVENFDEASKNEAN
What are the official names of this protein?
Transcription factor BTF3 homolog 4, Basic transcription factor 3-like 4.
What is the protein family that this protein belongs to?
Belongs to the NAC-beta family.
Protein: SYP_PSEAE
Sequence: MRTSQYLLSTLKETPADAVVISHQLLLRAGMIRRLASGLYTWLPMGLRVLRKVETIVREEMNAAGALEVLMPAVQPAELWQESGRWEQYGPELLRLKDRHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFHLSQDSLQQTYDGMYQAYSKIFSRLGLDFRPVQADNGSIGGSGSHEFHVLANSGEDDIVFSDSSDYAANIEKAEAVPRESARGSATEDMRLVDTPNTKTIAALVDGFQLPIEKTIKTLVVHGAEEGTLVALIVRGDHELNEIKAANQPLVASPLVFASEAEIRAAIGAGPGSLGPVNLPIACIVDRSVALMSDFAAGANIEDKHYFGVNWERDLPLPEVADLRNVVEGDPSPDGKGTLVIKRGIEVGHIFQLGTKYSEAMKLSVLSEQGKPVNLIMGCYGIGVSRVVAAAIEQNHDERGILWPSALAPFQIALVPLKYETESVKQATDKLYAELTAAGFEVLLDDRDKKTSPGVKFADMELIGIPHRIVISDRGLSEGVLEYKGRRDSESQNLPIGELMSFITEKLSR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16A2_GRAFK
Sequence: MSKPNQTLGEFIIENQSDFPGSSGELSRLINSLRLAAKVVNHEVNKAGLVDIIGAYGETNVQGEDQQKLDVYANNKFIQTLTNREIVCGIASEENDDFIQIEGHKGDHQNKYVVLMDPLDGSSNIDVNVSVGTIFSIYQRVTPVGTPVQKEDFLQPGNKQVAAGYIIYGTSTMLVYTTGHGVNGFTLNPALGSWYLSHPDMKFPEEGQIYSINEGNYIHFPQGVKDYIKYCQQEEGNRPYTSRYIGSMVSDIHRNMIKGGIFMYPKSSKASEGKLRLLYECNPFAFITEQAGGKASDGFQRIMDIDPTELHQRVPFFCGSKKMVEKAEEFMANAKANPQSQEFSFSSK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 2, FBPase class 1 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_PSEPK
Sequence: MLIKLPRSSECKASEITPEGIYLSRRTLLGGSLAGLALGALPGGVGAAQMSRYADVQAGAAPAWFTDKLAATRWQAVTVKDEAITPFKDATHYNNFYEFGPDKGDPAANGDSLKTEPWSIVVDGEVRKPGRYALEDFVKPYQLEERIYRLRCVEAWSMVIPWLGFPLAQVLKQVEPTSSARYVRFETLKDPQHMPGQRSGFALIDWPYREGLRLDEAMHPLAILAVGMYGRELPNQNGAPLRLVVPWKYGFKSIKSIVRISLVAEQPGTTWEGLAPDEYGFYANVNPTVDHPRWSQARERRLPSGLFSPNVRETQMFNGYADEVASLYTGLDLRKNY
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: DXR_PSEPG
Sequence: MSRPQRITVLGATGSIGLSTLDVIARHPDRYQAFALSGYSRVDELLALCVRHRPAFAVVPSAEAAARLRASLAAAGCATEVLEGEAGLCQVASAAEVDAVMAAIVGAAGLRPTLAAVEAGKKVLLANKEALVMSGALFMEAVRRSGAVLLPIDSEHNAIFQCMPGDYARGLSAVGVRRILLTASGGPFRETPVEALLDVTPEQACAHPNWSMGRKISVDSASMMNKGLELIEACWLFDAAPAKVEVVVHPQSVIHSLVDYVDGSVLAQLGNPDMRTPIANALAWPERIDSGVAPLDLFAIARLDFQAPDEQRFPCLRLARQAAEAGNSAPAVLNAANEVAVEAFLERRIRFPEIAGMIEQVLDQEPVVPLPSLDAVFAADQRARELSREWLRRHGR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RIMP_STRP3
Sequence: MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYELVDVEYDKMGSDYILSILVDKEDGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSSPGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHKIVNIPYQAVAKVRMAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_BACHK
Sequence: MSLLIDFIDETEEVKEEYVNLIREILGKAAQMEKIEDGAELSVTFVDNERIREINRDYRDKDQPTDVISFAMEEMGEGEMEIVGVEMPRMLGDLIISIPRAKEQAEEYGHSFDRELGFLALHGFLHLLGYDHMTEEDEKEMFGRQKEILEAFGLGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_KARMG
Sequence: MNKIKRLFINKKKNILNIYFTAGYPSIDSMPLILKRLQNLNIDIVEIGIPYSDPLADGNIIQKSNTKSLKNGMNISVLFYKLKKVKKYINIPIILMGYYNQFIKYGEIKFLEDCIESGVSGLILPDLPPRIYLNKYKKIFKKSKLAFIVLITPQTSLKRLKRLSSITDYFLYIVSSNSTTGTKNNINLSFLERIKEINVPKLIGFGICDKKSLNIAFKYAEGAIIGSAFIKAIKKSYLEKSIEKFIKYIIK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: KLH29_MOUSE
Sequence: MSRHHSRFERDYRIGWDRREWSVNGTHGATSVCSVTSGAGGSTASSLSARPGLLPLPVVPSRLPTPATAPAPCTTGSSEAITSLVVSSASAATTKAPGISKADNQSQGLTTSIRWGQTPVNQSTPWDTDEPPSKQMRESDNPGTGPWVTTVAAGNQPSLITHSYGVTQPPTFSPAVNVQAPVIGVTPSLPPHVGPQLPLIPGHYSLPQPPSQPLSSVVVNMPAQALYASPQPLAVSTLPGVGQVSRPGPTPVGNGHMAGPLLPPPPPAQPSAALPSSVPATNGPPTTDSAHGLQMLRTIGVGKYEFTDPGHPKEMLKELNQQRRAKAFTDLKIVVEGREFEVHQNVLASCSLYFKDLIQRSVQDSSQSSREKLELVLSNLQADVLELLLEFVYTGSLVIDSANAKTLLEAASKFQFHTFCKVCVSFLEKQLTASNCLGVLAMAEAMQCSELYHMAKAFALQIFPEVAAQEEILSISKDDFIAYVSNDSLNTKAEELVYETVIKWIKKDPATRAQYAAELLAAVRLPFIHPSYLLNVVDNEELIKSSEACRDLVNEAKRYHMLPHARQEMQTPRTRPRLSAGVAEVIVLVGGRQMVGMTQRSLVAVTCWNPQNNKWYPLASLPFYDREFFSVVSAGDNIYLSGGMESGVTLADVWCYMSLLDNWNLVSRMTVPRCRHNSLVYDGKIYTLGGLGVAGNVDHVERYDTITNQWEAVAPLPKAVHSAAATVCGGKIYVFGGVNEAGRAAGVLQSYVPQTNTWSFIESPMIDNKYAPAVTLNGFVFILGGAYARATTIYDPEKGNIKAGPNMNHSRQFCSAVVLDGKIYATGGIVSSEGPALGNMEAYEPTTNTWTLLPHMPCPVFRHGCVVIKKYIQSG
What are the official names of this protein?
Kelch-like protein 29, Kelch repeat and BTB domain-containing protein 9.
Protein: PCDGJ_HUMAN
Sequence: MGGSCAQRRRAGPRQVLFPLLLPLFYPTLCEPIRYSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEKLHFSVDAQSGDLLVKDRIDREQICKERRRCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLGMGTILESAEDPDISMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAHHLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILRVKATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDFEEVERYTINIEAKDRGSLSTRCKVIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDSGENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASIAQVSASDPDFGLNGRVSYSLIASDLESRTLSSYVSVSAQSGVVFAQRAFDHEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDTVPRAAQPGYLVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDFSDHPTPSDSQAEMQFYLVVALALISVLFLLAVILAIALRLRQSFSPTAGDCFESVLCSKSGPVGPPNYSEGTLPYAYNFCVPGDQMNPEFNFFTSVDHCPATQDNLNKDSMLLASILTPSVEADKKILKQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-B7, PCDH-gamma-B7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TRUB_XANOM
Sequence: MKPRIAYRPLHGILLLDKPAGLSSNNALQAARRLLRAEKGGHTGSLDPLATGLLPLCFGEATKIAGLLLGSAKAYDAEIVLGVTTDTDDADGEPLRERAVPDVSEADLQVALAAFIGRIQQQAPIYSALKQGGEPLYAKARRGEVIDAPVREVEVQAIEVLGYSAPRLTLRVTCGSGTYIRSLARDLGEVLGCGAHIASLRRLWVEPFRAPQMITLEGLATALEAGAEAQTVLLPIEAGLADFARIVLDAALAARFRMGQRLRDAAFPTGQVAVFGPDGSPSGLGLVDADGRLSPQRLFNGLNEISVC
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: NDHH_AETGR
Sequence: MSRPVRRKDLMIVNIGPHHPSMHGVLRLIVTLDGEDVVDCQPILGYLHRGMEKIAENRAIIQYLPYVTRWDYLATMFTEAITVNGPEQLGNIQVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFREREFVYDLFEAATGMRMMHNFFRIGGIAADLPYGWIDKCLDFCDYFLTEVVEYQKLITRNPIFLERVEGVGIIGGEEAINWSLSGPMLRASGIQWDLRKVDRYECYDEFEWEIQWQKQGDSLARYLVRLSEMTESIKIIQQALEGLPGGPYENLERRDFDKKLNSEMNSEWNNFDYRFISKKPSPTFELSKQELYVRVEAPKGELGIFLIGDQSGVPWRWKIRPPGFINLQILPELVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RS10_BACFN
Sequence: MSQKIRIKLKSYDHNLVDKSAEKIVRTVKATGAIVSGPIPLPTHKRIFTVNRSTFVNKKSREQFELSSFKRLIDIYSSTAKTVDALMKLELPSGVEVEIKV
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DIAA_ECOSE
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: CIP4_MOUSE
Sequence: MDWGTELWDQFEVLERHTQWGLDLLDKYVKFVKERAEVEQAYAKQLRSLVKKYLPKRPTKDDPEVKFSQQQSFVQLLQEVNDFAGQRELVAESLGIRVCLELAKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAHTAERLDQDINATKADVEKAKQQAHLRNHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELQVVPIIGKCLEGMKVAAESVDAKNDSQVLIELHKSGFARPGDLEFEDFSQVINRVPSDSSLGTPDGRPELRAASSRSRAKRWPFGKKNKPRPPSLSLLGGHLPSTLSDGPSSPRSGRDPLAILSEISKSVKPRLASFRSFRGGRGTVATEDFSHLPPEQQRKRLQQQLEERNRELQKEEDQREALKKMKDVYEKTPQMGDPASLEPRIAETLGNIERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHARPPDPPTTAPPDSSSSSTNSGSQDNKESSSEEPPSEGQDTPIYTEFDEDFEEPASPIGQCVAIYHFEGSSEGTVSMSEGEDLSLMEEDKGDGWTRVRRKQGAEGYVPTSYLRVTLN
What is the function of this protein?
Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis.  Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules.  Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex.  Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles.  Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells.  May be required for the lysosomal retention of FASLG/FASL (By similarity).  Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling.
What are the official names of this protein?
Cdc42-interacting protein 4, Thyroid receptor-interacting protein 10, TR-interacting protein 10, TRIP-10.
What is the protein family that this protein belongs to?
Belongs to the FNBP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection, phagocytic cup. Note=Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9 (By similarity). Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ.
Protein: CH602_SYNS3
Sequence: MAKRIIYNENARRALEKGIDILAEAVAVTLGPKGRNVVLEKKFGAPQIINDGVTIAKEIELEDHIENTGVALIRQAASKTNDAAGDGTTTATVLAHAMVKAGLRNVAAGANAITLKKGIDKASDFLVGKIQENAKPIADSNAIAQVGTISAGNDEEVGKMIADAMDKVGKEGVISLEEGKSMETELEVTEGMRFDKGYISPYFATDTERMEAVLDEPYILLTDKKIGLVQDLVPVLEQIARTGKPLLIIAEDIEKEALATLVVNRLRGVLNVAAVKAPGFGDRRKAMIEDMAVLTNGQLITEDQGLKLENAKLEMLGTARRVTINKDTTTIVAEGNEVAVSTRCEQIKKQMDETDSTYDKEKLQERLAKLAGGVAVVKVGAATETEMKDKKLRLEDAINATKAAVEEGIVPGGGTTLAHMAPALEEWAASNLSGEELIGANIVASALTAPLMRIAENAGVNGAVVAENVKSKSFNEGYNAANGEYVDMLSAGIVDPAKVTRSGLQNAASIAGMVLTTECIVADMPEKKEAAAAGGGMGGDFDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRF_HAEIG
Sequence: MSDSVILALGIAAFTVIVLVLVAIILFAKSKLVDSGDITIDINDDPEKAITLPAGGKLLGALASKGIFVSSACGGGGSCGQCIVKVKNGGGEILPTELSHINKREAKEGYRLACQVNVKGNMEVELPEEIFGVKKWECTVISNDNKATFIKELKLAIPEGEEVPFRAGGYIQIEAEPHVVNYKDFDIPEEYHEDWDKYDLWRYVSKVDEHIIRAYSMASYPEEKGIIMLNVRIATPPPRQPDAPPGQMSSYIWSLKAGDKVTISGPFGEFFAKETDAEMVFIGGGAGMAPMRSHIFDQLKRLHSKRKMSFWYGARSKREIFYQEDFDQLQAENDNFVWHVALSDALPEDNWTGYTGFIHNVLYENYLKNHEAPEDCEYYMCGPPVMNAAVIKMLKDLGVEDENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: UDP_HAEIN
Sequence: MSGVFHLNLTKAQLKGATLAIVPGDPARSERIAKQLDNPEFLTSTREFTSWLGYINGQPIVVCSTGIGGPSTSICVEELAQLGVRTFLRIGTTGAIQPHINVGDVLITTAAVRLDGASHHFVPLEYPAVANFECTTALYNAAKAKGIEPYVGVTVSSDTFYPGQERYDTYSGKVYRNYQGLLKQWQDLNVMNYEMESSTLFTMCSALGLRAGMVAGVIVNRTQQEIPNEATIKQTEEKAVSVVITAAQALLS
What is the function of this protein?
Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
What are the official names of this protein?
Uridine phosphorylase, UPase, UrdPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOA_THET8
Sequence: MEGLGIVFLAAVVLLFVFLFFSFIPVGLWISAWAAGVRVPLLTLVAMRLRRVPPAKIIYPLIKATKAGLDVRLDRLEAHYLAGGNVDRVVDALIAADKAGIKLTFDRAAAIDLAGRDVLEAVRVSVNPKVIQTPMVAAVAKDGIQLLATARVTVRANIDRLVGGAGEETIIARVGEGIVTTIGSANSHKEVLENPDRISKTVLEKGLDAGTAFEILSVDIADVDVGKNIGAQLQIDQAEADKKIAQAKAEERRAMAVAAEQENRALVEAMRAKLVEAQAQVPLALAEALRKGHLGVMDYYRLKNIEADTDMRESISRAAKPEGEE
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.