PharMolix/UniProtQA huggingface dataset:
Protein: FABZ_RICAE
Sequence: MIIDITEIMDWIPHRYPFLLVDRVLKIDPNKSITGIKNVTVNEPQFTGHFPARPVMPGVLMVEAMAQLAAVLVAKSLGSTKNKEVFLMTIENAKFRRIVQPGDTMYIHAVIDQQRANVWKFSSTVTVEGEIAAESKFTAMIKDKT
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_PSEP1
Sequence: MARYIGPKCKLSRREGTDLFLKSGVRALESKCNIEAAPGIHGQRRGRQSDYGTQLREKQKVRRIYGVLERQFRGYYQAAASKKGATGENLLQLLECRLDNVVYRMGFGSTRSESRQLVSHKAISVNGKTVNIPSYQVRPGDVVAVREKSLGQLRIVQALELCAQRGRVEWVDVDAAKKSGVFKNVPARSDLSADINENLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: SREA_ARTBC
Sequence: MLTLRSSSDTVRGFPATKRDMIRQPSAEDLDAAHQLVSSARGVADLRPDSFDASRSPDGDKASVDTGAAMDDTASSDQNHSESQQQQQQQQQQHSQASEQVSAPESSSRSRASPKASRNTEVFLGHQCVPTNRIRDSGANANSGYANSSTSDPRASPAASDASAQNASGCGSTPAGTCPGGGSCNGTGGAVGCDGCPAYNNRVYKAAPRAPSARQARASPSAQTSEEQAQSGLDALDSASQDASGMPKACQNCGTTLTPLWRRDDQGNTICNACGLYYRLHGSHRPVAMKKTVIKRRKRVVPALRDRSPGAGSSDNSSVSPELHSASLATSNADTNAYPPSENGGPSYGAAQFPHSAPPPIDFTGYYSKPTQSTSSPGLNTLINHSPNTKKRTHSESTSAESAPPATRIQSDISASAHLPPINPASARALPNSGRLSSISSLLNHTDPSFTESHVDAALGSNAPARSQTQTQPQPGTRSYSPNPVNPPTTQPAHGSHSIPPPPLTPAADDKVKAARRAQLQREAENMREALRAKERELASLK
What is the function of this protein?
GATA-type transcription repressor that regulates iron acquisition genes through specific binding the GATA sequence elements of target promoters (PubMed:26960149).  SreA targets include genes encoding a number of key iron-regulated factors such as the siderophore biosynthesis genes (PubMed:26960149).  Is dispensable for growth on keratin substrates (PubMed:26960149).  SreA represses the expression of hapX and the siderophore system during iron sufficient conditions by an iron-sensing mechanism, while hapX represses sreA and activates the siderophore system during iron-limiting conditions resulting in efficient iron uptake and inhibition of iron-consuming pathways (PubMed:26960149).
What are the official names of this protein?
GATA-type transcription factor sreA, Siderophore uptake regulator sreA.
What are the subcellular locations of this protein?
Nucleus.
Protein: GDL46_ARATH
Sequence: MVGPVRPQIVLFGSSIVQYSFTDRGWGATLADLYSRTADIILRGYAGWNSRFALKVLHQVFPKDAVIQPSLVIVYFGGNDSTHPHPSGHGPHVPLSEFIENMRKIGEHLLSLSDKTRVIFLTPPPMNEKQIEIVFGDAIKGRSNELCRPYAEELLNLCREINVKGIDIWTAIQQQDDWLNSCFTDGIHFTAKASEIVVKEILKVLRGADWKPSLYWKSLPVEFPFDFDAPNSISLHDLELTRNNHFESPHLVSLCEQELTRNEQLEPPHPVSLCDHELTRNEQLEPPHPVSLCDHELTQNEQLEPPQPTARL
What are the official names of this protein?
GDSL esterase/lipase At2g38180, Extracellular lipase At2g38180.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOA_HELP2
Sequence: MKDTLFNKSLNKRFCFDEKVAHVFDDMLERSIPYYHEMLNLGAYFIAQNLKENIHPKPLPKPLIYDLGCSTGNFFIALNQQIQQDIELVGIDNSMPMLKKAQEKLKDFNNVRFECMDFLEVEFKEASAFSLLFVLQFVRPMQREVLLKKIYNSLALNGVLLVGEKIMSEDRILDKQMIELYYLYKQNQGYSHNEIAFKREALENVLVPYSLKENVALLESVGFKHVEAVFKWVNFTLLVARKT
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: ILVC_STAA2
Sequence: MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIKSKSIEK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RK32_ORYSI
Sequence: MAVPKKRTSMSKKRIRKNLWKKKTYFSIVQSYSLAKSRSFSGVSEHPKPKGFSRQQTNK
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUVC_SYNPW
Sequence: MRILGIDPGLARVGYGVIETAGREQTMLDCGIIRTDSGRPEGERMVEIARDLRQLIRAWKPELAAVEKFFFYRSSNTIAVVQARGVVIMTLSRFGLPIVEFPPMQIKQALTGHGHADKDEVLEAVMRELSLETPPRPDDAADALAVALTGWFQR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CNOT9_XENTR
Sequence: MHSLATAAPVPAALAQVDREKIYQWINELSSPDTRENALLELSKKRESVPDLAPMLWHSFGTIAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQVLKDDTTTKRWLAQLVKNLQEGQVTDPRGIPLPPQ
What is the function of this protein?
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Involved in down-regulation of MYB- and JUN-dependent transcription.  Enhances ligand-dependent transcriptional activity of nuclear hormone receptors.  May play a role in cell differentiation.
What are the official names of this protein?
CCR4-NOT transcription complex subunit 9, Cell differentiation protein RQCD1 homolog, Rcd-1.
What is the protein family that this protein belongs to?
Belongs to the CNOT9 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, P-body.
Protein: POL_CAMVE
Sequence: MDHLLLKTQTQTEQVMNVTNPNSIYIKGRLYFKGYKKIELHCFVDTGASLCIASKFVIPEEHWVNAERPIMVKIADGSSITISKVCKDIDLIIAREIFKIPTVYQQESGIDFIIGNNFCQLYEPFIQFTDRVIFTKNKSYPVHIAKLTRAVRVGTEGFLESMKKRSKTQQPEPVNISTNKIENPLKEIAILSEGRRLSEEKLFITQQRMQKIEELLEKVCSENPLDPNKTKQWMKASIKLSDPSKAIKVKPMKYSPMDREEFDKQIKELLDLKVIKPSKSPHMAPAFLVNNEAEKRRGKKRMVVNYKAMNKATIGDAYNLPNKDELLTLIRGKKIFSSFDCKSGFWQVLLDQESRPLTAFTCPQGHYEWNVVPFGLKQAPSIFQRHMDEAFRVFRKFCCVYVDDILVFSNNEEDHLLHVAMILQKCNQHGIILSKKKAQLFKKKINFLGLEIDEGTHKPQGHILEHINKFPDTLEDKKQLQRFLGILTYASDYIPKLAQIRKPLQAKLKENVPWKWTKEDTLYMQKVKKNLQGFPPLHHPLPEEKLIIETDASDDYWGGMLKAIKINEGTNTELICRYASGSFKAAERNYHSNDKETLAVINTIKKFSIYLTPVHFLIRTDNTHFKSFVNLNYKGDSKLGRNIRWQAWLSHYSFDVEHIKGTDNHFADFLSREFNKVNS
What is the function of this protein?
Encodes for at least two polypeptides: protease (PR) and reverse transcriptase (RT).  The protease processes the polyprotein in cis.  Reverse transcriptase is multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated, and reverse-transcribed inside the nucleocapsid.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA) (By similarity).
What are the official names of this protein?
Enzymatic polyprotein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae enzymatic polyprotein family.
Protein: NUOB_LEGPH
Sequence: MAVAELEKKGFELTTVEKLVGWARSGSMWPMTFGLACCAVEMMHVGAARYDLDRFGIIFRPSPRQSDVMIVAGTLCNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALLYGIIQLQNKIRRKPVLEA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UBP37_HUMAN
Sequence: MSPLKIHGPIRIRSMQTGITKWKEGSFEIVEKENKVSLVVHYNTGGIPRIFQLSHNIKNVVLRPSGAKQSRLMLTLQDNSFLSIDKVPSKDAEEMRLFLDAVHQNRLPAAMKPSQGSGSFGAILGSRTSQKETSRQLSYSDNQASAKRGSLETKDDIPFRKVLGNPGRGSIKTVAGSGIARTIPSLTSTSTPLRSGLLENRTEKRKRMISTGSELNEDYPKENDSSSNNKAMTDPSRKYLTSSREKQLSLKQSEENRTSGLLPLQSSSFYGSRAGSKEHSSGGTNLDRTNVSSQTPSAKRSLGFLPQPVPLSVKKLRCNQDYTGWNKPRVPLSSHQQQQLQGFSNLGNTCYMNAILQSLFSLQSFANDLLKQGIPWKKIPLNALIRRFAHLLVKKDICNSETKKDLLKKVKNAISATAERFSGYMQNDAHEFLSQCLDQLKEDMEKLNKTWKTEPVSGEENSPDISATRAYTCPVITNLEFEVQHSIICKACGEIIPKREQFNDLSIDLPRRKKPLPPRSIQDSLDLFFRAEELEYSCEKCGGKCALVRHKFNRLPRVLILHLKRYSFNVALSLNNKIGQQVIIPRYLTLSSHCTENTKPPFTLGWSAHMAISRPLKASQMVNSCITSPSTPSKKFTFKSKSSLALCLDSDSEDELKRSVALSQRLCEMLGNEQQQEDLEKDSKLCPIEPDKSELENSGFDRMSEEELLAAVLEISKRDASPSLSHEDDDKPTSSPDTGFAEDDIQEMPENPDTMETEKPKTITELDPASFTEITKDCDENKENKTPEGSQGEVDWLQQYDMEREREEQELQQALAQSLQEQEAWEQKEDDDLKRATELSLQEFNNSFVDALGSDEDSGNEDVFDMEYTEAEAEELKRNAETGNLPHSYRLISVVSHIGSTSSSGHYISDVYDIKKQAWFTYNDLEVSKIQEAAVQSDRDRSGYIFFYMHKEIFDELLETEKNSQSLSTEVGKTTRQAL
What is the function of this protein?
Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry.  Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex.  Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro.  Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2) (PubMed:21596315).  Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1 (PubMed:27296872).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 37, Deubiquitinating enzyme 37, Ubiquitin thioesterase 37, Ubiquitin-specific-processing protease 37.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: Y1277_LACDA
Sequence: MAYRQSFYQFLMTLRDPDSNGDLAQFANNAQFDSTFPRQEQDRTRLSEYLEENAAYLPSMTIFDDAYQAYEEKMQY
What are the official names of this protein?
UPF0346 protein Ldb1277.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: RSPB_ECOLI
Sequence: MKSILIEKPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGVHADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTENDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPLGEIFTEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKELSIFSSRLNANKFPIVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEQDQKHCCKVLLTFSE
What is the function of this protein?
Not known; probable catabolic enzyme.
What are the official names of this protein?
Starvation-sensing protein RspB.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: CS2H2_ACITH
Sequence: MSLKQQLESDFEGHKRWALRRQMGIPNNRRLWVCACMDERLPVDDALGIRGDRGDAHVFRNAGGLITDDAIRSAMLTCNFFGTEEIVIINHTECGMMSAQTDTIVKALKDKGIDLDNLQLDPDLPELTLKAGMFGKWVKMYQDVDETCARQVEYMRNHPLIPKHVTISGWIWEVETGHLRPPHFRIGEKVNTNKAMGAK
What is the function of this protein?
Catalyzes the conversion of carbon disulfide into hydrogen sulfide and carbon dioxide, with carbonyl sulfide as an intermediate.  Likely plays a key role in sulfur metabolism that allows A. thiooxidans G8 to grow on carbon disulfide as the main carbon and energy source.  Does not show carbonic anhydrase activity (hydration of CO(2) to carbonate).
What are the official names of this protein?
Carbon disulfide hydrolase, CS(2) hydrolase.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family.
Protein: KHSE_LISMO
Sequence: MRIRVPATTANLGPGFDSCGLALTLYLTLDIGAEADSWYIEHNIGGGIPHDETNVIIETALNLAPNLTPHHLVMTCDIPPARGLGSSSAAVVAGIELANTLAELNLSKEEKVRIAAEIEGHPDNVAPAVLGNWVVGAKLDGEDFYVRHLFPDCALIAFIPKAELLTSESRGVLPDTLPFKEAVQASSIANVMIAAILRNDMTLAGEMMERDLWHEKYRSQLVPHLAQIRDVAKNQGAYAACLSGAGPTVLVFAPRNLANKLQTSLQTLEIDADVLLLDVEGSGAEVFR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_FERNB
Sequence: MAKCEICGKEPRAGKNVSHSNRHTNRWFKPNVQKVRVLLDDGTVKRMNVCTSCLKAGKVRRYVSKSQSVALEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RL18_DESDA
Sequence: MKYSKNESRQRRKIRISKKVSGTAERPRLVVYRSNLHVYAQIVNDLDGATLVATSTLALGKNESGLHCNKGGAEKVGIEIARMAKEKNIDKVVFDRNGYLYHGRVKAVADGAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: YGJR_ECOLI
Sequence: MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFANDFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQTQLFLSHKINVICEKPLASNLAEVDAAIACARENQVVLFEAFKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYLDGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAQGVVVMDYGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHINTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVIFPADSVKL
What are the official names of this protein?
Uncharacterized oxidoreductase YgjR.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: HRCA_THEYD
Sequence: MRDTMLDERTKKVLYAVVESYIEKPEPVGSRYIMKKYGFDVCSATIRNIMSDLEDAGFLSQPHTSAGRVPTDKAYRFYVDYIFQSELFSQSLEIKRVIENLTKKLRKLRNNMNSLFLETTQSLSQATRYLGLALLPATEKTALHRVDFIKFKDDLVIAVVVNDKGIVKNKIIKVYPEITQKELNSLADFVNRNYHGKTIDEIRDDLIVRIKKEKIFWDRLISKILKMCQEALYFSREDVYVSGFYHIMHLPDFSDIEKLREVAKTIQDRHLLLKLFENISEDDEVKVIIGQENPVEEFRSFSIIASPYKEKDKSLGVIALVGPKRMNYQRAIMLVNAFARSLTRTLSD
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RBS2_HYDMR
Sequence: MSIQTDDYRTKYTLETFSFLPEFTADEIYDQIVYIINQGWTPALEHEAPEAASSHYWGMWKLPMFGTRDPNAVLAEIDQCRAAYPNHMIRLIGYDNYTQCQGHNFCRFTVLGECNSHGTNNE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit 2, RuBisCO small subunit 2.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysome.
Protein: LIPL5_CAEEL
Sequence: MWRFAVFLAAFFVQDVVGSHGDPELHMTTPQIIERWGYPAMIYTVATDDGYILEMHRIPFGKTNVTWPNGKRPVVFMQHGLLCASSDWVVNLPDQSAGFLFADAGFDVWLGNMRGNTYSMKHKDLKPSHSAFWDWSWDEMATYDLNAMINHVLEVTGQDSVYYMGHSQGTLTMFSHLSKDDGSFAKKIKKFFALAPIGSVKHIKGFLSFFANYFSLEFDGWFDIFGAGEFLPNNWAMKLAAKDICGGLKVEADLCDNVLFLIAGPESDQWNQTRVPVYATHDPAGTSTQNIVHWMQMVHHGGVPAYDWGTKTNKKKYGQANPPEYDFTAIKGTKIYLYWSDADWLADTPDVPDYLLTRLNPAIVAQNNHLPDYNHLDFTWGLRAPDDIYRPAIKLCTDDYLGK
What is the function of this protein?
Lipase involved in lipid homeostasis (PubMed:31676440).  Regulates mitochondrial lipid composition, in particular cardiolipins and coenzyme Q-9 levels, in response to nutrient availability (PubMed:31676440).  Does not affect global triglyceride levels in response to nutrient availability (PubMed:31676440).  However, in coelomocytes, specifically promotes triglyceride catabolism and lifespan extension in response to nutrient deprivation (PubMed:31340142).
What are the official names of this protein?
Lipase lipl-5, Lipase-like 5.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Lysosome lumen. Secreted. Note=Localizes to lysosomes in coelomocytes.
Protein: PYRE_CALS4
Sequence: MEKEKVLEIFEKLEVINKGHFLLSSGKHSDTYLQCAKIFQYPNYSEIFSRELAEKFKGYRIDVVIGPAIGGIILAYEVARQIGVRALFAEREDNVMKLRRGFEISKGERVLVVEDVVTTGGSVKEVIELVRSLGGEVIGVGTIVDRSDGKIDFGVPFESIVKLQIKTYEKEECPLCKEGIPLVKPGSRKL
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: Y012_NPVAC
Sequence: MYRHACYLYIISQGGELLSVAIIKEWPSVFITSLAASTMKRRHCKLNSLPQELFDKIVEYLSLSDYCNLVLVCKRPSSKYNVIFDSTNHQHLKGVYKKTDVQITSYNEYINCICNELRQDEFYAKSSWIASICGHQRATIFSVTNKQVEMKYHLYNIAIVESEDCNGFYPFEPTRDCLICKQKNQCPRNSFIVSLCKYLEKQNVQSNFIYYLYEINT
What are the official names of this protein?
Uncharacterized 14.2 kDa protein in PK1-LEF1 intergenic region, ORF11.
Protein: QUEC_PSESM
Sequence: MTNTEKRAVILLSGGLDSATVVAMARAEGYACYTMSFDYGQRHRAELDAAARVARDLGAVEHKVIGLNLSGIGGSALTDSSIAVPESPSEGIPVTYVPARNTVFLSLALGWAEVLGARDIFIGVNAVDYSGYPDCRPEFVESFERMANLATKAGVEGQGFTIRAPLQNLSKSDIVKAGIALGVDYALTVSCYQADDQGRACGKCDSCRLRAEGFTASGMSDPTRYF
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: NU4LM_VARRB
Sequence: MPSIFINIILAFIIALLGMLIFRSHLMSSLLCLESMMLSMFILSTLTILSLHLTMSFMMPILLLVFAACEAAVGLALLVTVSNTYGLDYIQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRHO_RHOOB
Sequence: MAVPKIVLFYVFTPLADPEAIRLWQYTLAEAHDLTGRILVSEHGINATVGGDIRDVKRYVKGTRSYAPFKDADIKWSDGLGNDFPRLSVKVRPEIVTFGAPGELKVDADGVVGGGTHLAPEEVHRLVEGRGDDVVFFDGRNGFEAEIGRFRDAVVPDVSTTRDFVHELDSGKYDHLKDKAVVTYCTGGVRCEVLSSLMRSRGFGEVYQLDGGIVRYGEAFGDTGLWEGSLYVFDKRMTIEFSDQAKTLGRCTRCGGPTSRYENLPDDRGRELVLVCAGCTENRAG
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: NPIIB_TRIRU
Sequence: MQVIVALAALSSLAAPALGFSIPRGVPVSQSMIDVKLSATGNSMVKATITNNGNRALNLLKFHTIMDSNPTRKVSIESEDGKEIQFTGMMPTYKEKDLKPSYFISLPPKGTVEHSFDIARTHDLSRGGKFTLKAEGMVPIAEENGTEITGAAKYHSNELHMTIDGEKAASVENAFGIVKRGPRSRITKRTSIDMQSCGNSQELQALTAALKASAQLSSMSAQAVSQNQDKYMEYFKDPQYMQTVQSRFQAVAQESSSTTGGGTTYHCSDTMGGCEEGVLAYTLPSQNEVFNCPIYYSDLPPLSNECHAQDQATTTLHELTHNPAVQEPFCEDNGYGYERATALSAEKAVQNADSYALFANAIYVGC
What is the function of this protein?
Probable secreted metalloprotease that shows high activities on basic nuclear substrates such as histone and protamine (By similarity).  May be involved in virulence.
What are the official names of this protein?
Probable neutral protease 2 homolog B, Deuterolysin B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SNAF_LYCMC
Sequence: MNFFILIASACLVLTGVQCRKDGYLYDSKNCKYACVDNDYCLKECKSKGGYYGYCYRWYSSCYCEGLPDKVKTEKTGRCTL
What is the function of this protein?
Binds voltage-independently at site-3 of voltage-gated sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin LmNaTx15.1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.