PharMolix/UniProtQA huggingface dataset:
Protein: CRCB_VIBVU
Sequence: MSQFAILGFIALGGAFGACSRYLVSELCVVLLGRGFPYGTLTVNVVGSFIMGLLIAAFESELLATEPWRQIIGLGFLGALTTFSTFSMDNVLLMQQGAFFKMGLNVVLNVTLSITAAWVGFQLLKS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CC181_HUMAN
Sequence: MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTFKNYFENERNMFGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELLNLQDIASQGFLPPINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPLNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRQENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFRFTDHYN
What is the function of this protein?
Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
What are the official names of this protein?
Coiled-coil domain-containing protein 181.
What is the protein family that this protein belongs to?
Belongs to the CCDC181 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Note=Localizes to the microtubular manchette of elongating spermatids. Localizes to the sperm flagella and to the basal half of motile cilia.
Protein: KDPA_ECOL5
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVERVLFSALGVSDREMNWKQYLSAILGLNILGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMNTLGNAWVDLLRITLWVLTPVALLIALFFIQQGALQNFLPYQAVTTIEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTVLTNFVQMLAIFLIPTALCFAFGEVAGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLALCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PBL9_ARATH
Sequence: MGICLSAQVKAESSGASTKYDAKDIGSLGSKASSVSVRPSPRTEGEILQSPNLKSFSFAELKSATRNFRPDSVLGEGGFGCVFKGWIDEKSLTASRPGTGLVIAVKKLNQDGWQGHQEWLAEVNYLGQFSHRHLVKLIGYCLEDEHRLLVYEFMPRGSLENHLFRRGLYFQPLSWKLRLKVALGAAKGLAFLHSSETRVIYRDFKTSNILLDSEYNAKLSDFGLAKDGPIGDKSHVSTRVMGTHGYAAPEYLATGHLTTKSDVYSFGVVLLELLSGRRAVDKNRPSGERNLVEWAKPYLVNKRKIFRVIDNRLQDQYSMEEACKVATLSLRCLTTEIKLRPNMSEVVSHLEHIQSLNAAIGGNMDKTDRRMRRRSDSVVSKKVNAGFARQTAVGSTVVAYPRPSASPLYV
What is the function of this protein?
Possible bi-functional kinase.  In vitro, it exhibits serine/threonine activity.  In vivo, can phosphorylate tyrosine residues of limited substrates (PubMed:1450380).  May be involved in plant defense signaling (By similarity).
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL9, PBS1-like protein 9, Protein kinase 1A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DXR_CROS5
Sequence: MKKISLLGSTGSIGTQTLDIVNQYPDQFQVVGLATRSNVELLATQVQQFRPEIVAICDESKLGSLKDAIASMDYSPLILAGEQGVAEVARHGDAESVVTGIVGCAGLLPTIAAIEAGKDIALANKETLIAGGPVVLPLIEKHGVKLLPADSEHSAIFQCLQGVPDGGLRRIILTASGGAFRDWPVEQLKYVTVQDALKHPNWSMGQKITVDSATLMNKGLEVIEAHFLFGMDYENIDIVIHPQSIIHSLIEVQDTSVLAQLGWPDMRLPLLYALSWPERIYTDWEQLDLVKAGSLTFREPDHDKYPCMQLAYAAGNAGGAMPAVLNAANEQAVALFLAEKIAFLDIPKVIEKTCDNFRDHNRSQPSLEDILEADKWAREAVLMAAEGLGTENKVVSLK
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MARC_SALTY
Sequence: MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSYMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAHESPEAKSKSEELADEPTANIAFVPLAMPSTAGPGTIAMIISSASTVRHGGEFPDWVIMVAPPIIFLAVAVILWGCLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH
What are the official names of this protein?
UPF0056 inner membrane protein MarC.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SFSB_ECOLI
Sequence: MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSRPWPKGEMIIAKALGTDPWVIWPSRYHDPQTHEFIDRTQLMRSYTKPKK
What is the function of this protein?
This protein is involved in positive regulation of the metabolism of sugars.
What are the official names of this protein?
Sugar fermentation stimulation protein B, Ner-like protein.
What is the protein family that this protein belongs to?
Belongs to the ner transcriptional regulatory family.
Protein: G6PI_FRAT1
Sequence: MLFCDDSKKYLKEQNINLKNEFDKDDKRVEKFSLKHQNIYFDYSKNLINDYILKSLLESAEKSSLKDKIKQMFNGAKINSTEHRAVLHTALRDLSSTPLIVDGQDIRQEVTKEKQRVKELVEKVVSGRWRGFSGKKITDIVNIGIGGSDLGPKMVVRALQPYHCTDLKVHFVSNVDADSLLQALHVVDPETTLFIIASKSFSTEETLLNSISAREWLLDHYEDEKAVANHFVAISSKLDKVKEFGIDLEHCYKMWDWVGGRYSLWSSIGMSIAFAIGYDNFEKLLAGAYSVDKHFKETEFSKNIPVIMALLASYYSCTYNSQSQALLPYDERLCYFVDYLQQADMESNGKSVNIAGETVNYQTGVVLWGGVGTNGQHAFHQLLHQGNIFIPVDFIAIATSHHNYDNHQQALLANCFAQSQALMFGQSYDMVYNELLKSGLNETQAKELAAHKVIPGNRPSTTILLDELSPYSLGALIALYEHKIFVQGVLWDINSYDQWGVELGKKLGKNILKAMNDDSSDEYQNLDDSTRQLIAKVKNK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHG29_RAT
Sequence: MIAHKQKKAKKKRVWASGQLSAAITTSEMGLKSVSSNSIFDPEYIKELVNDIRKFSHVLLYLKEAILSDCFKEVIHIRLDELLHMSKHQNLNSVDLQNAAETLASKVKAVNFTEVNDENKNDLFREVFSSIETLAFTFGNILTNFLMGDVGNDSILRLPISRESKSFENISMDSVDLPHEKGNFSPIELDNLLLKNSDSIELALSYAKTWSKYTKNIVSWVEKKLNLELESTRNIVKLAEATRSSIGIQEFMPLQSLFTNALLNDIHSSHLLQQTIAALQANKFVQPLLGRKNEMEKQRKEIKELWKQQQNKLLETETALKKAKLLCMQRQDEYEKAKSSMFRAEEEQLSSSVGLGKNLNKLLEKRRRLEEEALQKVEEANEHYKVCVTNVEERRNDLENTKREILTQLRTLVFQCDLTLKAVTVNLFHMQQLQAASLANSLQSLCDSAKLYDPGQEYSEFVKATSSSELEEKVDGNVNKQIASSPQTSGYEPADSLEDVARLPDSCHKLEEDRCSNSADMTGPSFIRSWKFGMFSDSESTGGSSESRSLDSESISPGDFHRKLPRTPSSGTMSSADDLDEREPPSPSEAGPNSLGTFKKTLMSKAALTHKFRKLRSPTKCRDCEGIVMFPGVECEECLLVCHRKCLENLVIVCGHQKLQGKMHIFGAEFIQVAKKEPDGIPFVLKICASEIESRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSSHDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQEAKKDSPEDKKHPHVSIEINRILLRSKDLLRQLPASNFNSLHYLIVHLKRVVDHAEENKMNSKNLGVIFGPTLIRPRPTTAPVTISSLAEYSSQARVVEFLITYAQKIFDGSLQPQAGVIANTGAIAPQVDHGCHPKPLLSPDERDSDHSLKQLFFSSKEDIRTMDCESKTFELTTSFEESERKQNALGKCDAPILDNKVHLLFDQELESASHKTEDTCKSPKLLLLRSDRVANSVQRPTPRTRLRPVSLPVDRLLLLAGSPTERSSRNTGNTDSDKFGKNAAFEGLHRKDNSNTTCSKVNGFDQQNVQKSWDKQNERNSFTAKTTVIIPSAYAEKGLAVSTGNNRGHSSGAAQPSKAHADPARSARDTSEHSSSDSCPVAAVRAPRTLQPQHWTTFYKPPNPTFNVRGTEEKTAFPSAAVPPVLVHAPQSHVAKSDPDLEATLACPVQTSGQPKESSEEPGLPEGTPTCQRPRLKRMQQFEDLEDEIPQFV
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.  Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42.  May act as a specific effector of RAP2A to regulate Rho (By similarity).  In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis (By similarity).
What are the official names of this protein?
Rho GTPase-activating protein 29, Rho-type GTPase-activating protein 29.
Protein: KC1G1_DANRE
Sequence: MDHPREKEADRPVRSSKVPQGRSGHSRPSSSSASSGVLMVGPNFRVGKKIGCGNFGELKLGKNLYTNEYVAIKLEPVKSRAPQLHLEYRFYKTLGSADGLPQVFYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHIIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRNLFTELFDRKGYAFDYSYDWVGRQIPTPVGTVHVDSGASAITRESHAHRDRPSQHQPLRNQVVSSTNGELNADDPLAAHSNAPITAQAEVEVVDEAKCCCFFKRKRKKNTPRHK
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins.  Participates in Wnt signaling (By similarity).
What are the official names of this protein?
Casein kinase I isoform gamma-1, CKI-gamma 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL252_YEAST
Sequence: MSLQYFGTLTYLIKTQRLWRKTRYLFIIHPWSNNWIRNPDFENIWNSTSIFIRPCSLGYWNSIYLIDFRQRADQLHKYLSHQSWLAICFSFTDVLGQEQFI
What are the official names of this protein?
Putative uncharacterized protein YLR252W.
Protein: SUHR_RHIME
Sequence: MARTPAKYCDLVMKGGITSGIVYPNAALALARDYRFKNIGGTSAGAIAAAACAAAAVGDRRKQMKAAIAQPEERVGFEGLAKASANLASPGFIKDLLQPAAGAGQAFRLLVTLAGNTGVLRKGVALLGSVVRIAPVETLLLLAALAGLAYAVGGQTGMIAAALPAAICAYLGGVVFAVLRIARVLRRNLMGLCTGTAPDQPARRPRMVLTDWLHETLQALSGKASGQPLTFGDLWTAERYPGEPGSDRAVTLKMITTGISHQEPRSLPFESALFWFRRKEFEALFPKVVVDWMVEKAGEPVTVAGEDYYLLPHGADMPVLVATRMSLSFPLLISAVPLHEPARRESLPGSDGENEAEDTTSDEDEQKTVLDSTEALTTGGKKRRARPAAFRICWFSDGGISSNFPIHLFDRALPRWPTFAINLVYPETSDTGSRPEVFLPENNRQGWQRHYQPIARKSAVHELCAFVFAIVATMQNWRDLLQSRAPGHRERIVHVSLSPQEGGLNLAMSKEVLAAVSKKGTAAGEAFARFSFENHYWIRWRNLASALQRYTIDIAASDAYRPKIPDYEPAYALAHDATSKPPSYRFASKAEREEAARLLEKLIGEGEKWSGEGPDLTKTAPRPLPQLQIAPTY
What is the function of this protein?
This protein is non-essential for R. meliloti growth, but induces a heat-shock response in temperature-sensitive E. coli K165 by elevating levels of sigma 32 (mechanism unknown).
What are the official names of this protein?
RpoH suppressor.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1167_STRR6
Sequence: MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEEFGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEILTSIDNRE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein spr1167.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: RL20_STRPB
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVADAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CSTFT_MOUSE
Sequence: MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQPVSGPGPGGPGPSGPGGPGPGPAPGLCPGPNVMLNQQNPPAPQPQHLPRRPVKDIPPLMQTSIQGGIPAPGPIPAAVPGPGPGSLTPGGAMQPQVGMPVVGPVPLERGQMQISDPRPPMPRGPMPSGGIPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYMGPPHQGPPMHHGHDNRGPASHDMRGGPLAADPRMLIGEPRGPMIDQRGLPMDGRGGRESRGMETRPMETEVLEPRGMERRMETCAMETRGMDARGLEMRGPGPSSRGPMTGGIQGPGPINMGAGGPQGPRQVPNIAGVGNPGGTMQGAGIQGGGMQGAGMQGGGMQGAGMQGGGMQGAGMQAGMQGASMQGGMQGAGMQGASKQGGGQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS
What is the function of this protein?
May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells.  Directly involved in the binding to pre-mRNAs.
What are the official names of this protein?
Cleavage stimulation factor subunit 2 tau variant, CF-1 64 kDa subunit tau variant, Cleavage stimulation factor 64 kDa subunit tau variant, CSTF 64 kDa subunit tau variant, TauCstF-64.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEPA_SYNS9
Sequence: MTDAPVSRIRNFCIIAHIDHGKSTLADRLLQDTGTVANRDMQEQFLDNMELERERGITIKLQAARMNYTAADGEQYVLNLIDTPGHVDFSYEVSRSLLACEGALLVVDASQGVEAQTLANVYLALENDLEIIPVLNKIDLPGADPDRIKEEVEAIIGLDCSNAIYCSAKTGLGVPEILQAVVDRVPAPADAVEEPTKALIFDSYYDPYRGVIVYFRVMSGRISCKDKVLLMASKKTYELDEIGIMAPNERKVEELHAGEVGYLAASIKAVADARVGDTITLFNAPADEELPGYAEAKPMVFCGLFPTEADQYPDLREALHKLQLSDAALKFEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYDLDLIVTAPSVIYNVNMVDGSEELVDNPATLPDPQKRESIEEPYVRMEIFAPNDYNGALMGLCQERRGEYIDMKYITKDRVTLIYELPLAEVVTDFFDQMKTRTQGYASMEYHLIGYRKNQLVRLDVLINGDRADPLTTIVHQDKAYNVGKALVDKLKELIPRQQFKIPLQASIGSRIIASTSISAIRKDVLAKCYGGDISRKKKLLKKQAKGKKRMKAMGKVDVPQEAFMAVLKLND
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YIDD_LEGPL
Sequence: MGKINLMLRQIVCLPIKMYQYFISPLITPCCRYYPSCSEYADSAIKHYGVIKGLLMALNRLSRCHPWSKGGYDPLFPNDKN
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LEXA_SHEB9
Sequence: MRPLTPRQAEILELIKRNIADTGMPPTRAEIATRLGFKSANAAEEHLKALAKKGCIEIMPGTSRGIRLTAEVEEVTETGLPLIGQVAAGEPILAQEHVEQYYQVDPSMFHPAADFLLRVKGDSMKNIGILEGDLLAVHKVQQARNGQVVVARVDDDVTVKRFEKKGNVVYLHAENEDYSPIKVDLGYQSLTIEGLAVGVIRNGDWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: GPMI_VIBPA
Sequence: MSAKKPLALVILDGYGYREDTASNAIANAKTPVMDALIANNPHTLISASGMDVGLPDGQMGNSEVGHTNIGAGRVVYQDLTRITKSIADGEFEQTPALVEAIDAAVKAEKAVHIMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHCFLDGRDTPPRSAENSLQRFQDLFAKLGKGRVASLVGRYYAMDRDNNWERVQVAYDLLTQAKAEFTAETAVAGLEAAYARDENDEFVKATAIKAEGQEDAIMQDGDAVIFMNYRADRARQITRAFVPGFDGFERAVFPAINFVMLTQYAADIPLATAFPPASLENTYGEWLSKQGQTQLRISETEKYAHVTFFFNGGVENEFEGEERQLVASPKVATYDLQPEMSSPELTEKLVAAIKSGKYDTIICNYPNADMVGHTGVYEAAEKAIEALDESVGKVVEAIKEVGGQLLITADHGNAEMMIDPETGGVHTAHTNLPVPLIYVGDKAVEFKEGGKLSDLAPTMLSLAGLEIPAEMSGDVLVK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: NUOB_BURCH
Sequence: MSIEGVLKEGFVTTTADKLINWTRTGSLWPMTFGLACCAVEMMHAGAARYDLDRFGVVFRPSPRQSDVMIVAGTLCNKMAPALRRVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGVIQLQAKIRRTNTIARQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UPP_ALKOO
Sequence: MSKVTVIDHPLIQHKLTLIRDKNTGSKDFRALVREISMLMGYEVTRDLSLEEIEIETPVCTTKAKTLTGRKLGIVPILRAGLGMVDGILELIPAAKVGHVGLYRDPETLEPVEYYVKLPTDVHERELIVLDPMLATGGSANAAIQFIKDRGATNIKLVCLVSCPQGIAAVQEAHPDVDIYVAAIDETLDDHAYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RIMM_PROMT
Sequence: MFEKDKWMTIGEIVAPQGLRGDLRIKPSSDFPERFTKPGKRWIQKTDELPTEIKLTKGKLIPGKSIYVLSIEGVSTRSSAEEIIGWKLVIPIDSRPMLSKDEYHYHDLIGLEARRGPSKALIGYVTDLIKGGNDLLEIELVEGKKVLVPFVKEIVPEIEIKEKWLLINPPPGLLEL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNJC2_HUMAN
Sequence: MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFEVFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKTWNHFSDNEAERVKMMEEVEKLCDRLELASLQCLNETLTSCTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKNTEKSTGGGGNGSKNWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATPSERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKKAAQEQVLNASRAKK
What is the function of this protein?
Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus.  When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state.  In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain.  When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
What are the official names of this protein?
DnaJ homolog subfamily C member 2, M-phase phosphoprotein 11, Zuotin-related factor 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: SYFA_HELPS
Sequence: MHTLIERLEKVTNSKELEEARLSALGKKGVFADKFNQLKNLNGEEKNAFAKEIHHYKQAFEKAFELKKKAILELELEERLKKEKIDVSLFNAIKTSSSHPLNHTKNKIIEFFTPLGYKLEIGSLVEDDFHNFSALNLPPYHPARDMQDTFYFKDHKLLRTHTSPVQIHTMQEQTPPIKMICLGETFRRDYDLTHTPMFHQIEGLVVDQKGNIRFTHLKGVIEDFLHYFFGGVKLRWRSSFFPFTEPSAEVDISCVFCKQEGCRVCSHTGWLEVLGCGMVNNAVFEAIGYENVSGFAFGMGIERLAMLTCQINDLRSFFETDLRVLESF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DJC30_HUMAN
Sequence: MAAMRWRWWQRLLPWRLLQARGFPQNSAPSLGLGARTYSQGDCSYSRTALYDLLGVPSTATQAQIKAAYYRQCFLYHPDRNSGSAEAAERFTRISQAYVVLGSATLRRKYDRGLLSDEDLRGPGVRPSRTPAPDPGSPRTPPPTSRTHDGSRASPGANRTMFNFDAFYQAHYGEQLERERRLRARREALRKRQEYRSMKGLRWEDTRDTAAIFLIFSIFIIIGFYI
What is the function of this protein?
Mitochondrial protein enriched in neurons that acts as a regulator of mitochondrial respiration (By similarity).  Associates with the ATP synthase complex and facilitates ATP synthesis (By similarity).  May be a chaperone protein involved in the turnover of the subunits of mitochondrial complex I N-module.  It facilitates the degradation of N-module subunits damaged by oxidative stress, and contributes to complex I functional efficiency (PubMed:33465056).
What are the official names of this protein?
DnaJ homolog subfamily C member 30, mitochondrial, Williams-Beuren syndrome chromosomal region 18 protein.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RIMM_RHOPA
Sequence: MPSGLICVARIGAPHGVRGAVRLWSFTADPFAVSDYGPLVTKDGARQFEIASAREAKSHLVVTLKGVTTRDEAERLNGVELYVARDKLPPTEADEYYHADLIGLAAVTTTGDPLGKVVAIHNFGAGDIIEIAPPSGPTLLLPFTNAVVPTVDLAVGQVVIEPPNEIEGDTPNHPEA
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.