PharMolix/UniProtQA huggingface dataset:
Protein: SRDH_NEUCR
Sequence: MTFKVIIVGGGPVGLYMAHAFERANIDYVILEQQDTVLNISGQLLFTWPQTVRLFDQIGLLADLENVALGIHHKKRLFGDNGQVTTTSNFWDAMQDNHGYPFLPLLRSELVKILYNHLKGRESNIRVNSRVTDIRPHATGVHVHLADGSLIQGSIVVGADGVHSRTRQIMDSLVAQHALNPARLANKPMVSTFYGIFGRASNVDLGIEPEVFFESRGGGGEGGAVVQCLATKDIVQFVTLKPLPGGPTSERSPRYSDEEMDAYAASLADVAVCPGVKFGDVWAKVQRKSTRMLNQEEGFLDNWFFDRIVLVGDAVHKSTSVNGLGMTCGLHSGAVLANELHSLLSRQREKEEEPSTEELEGAFGRYQEDRKTEVKPIWNGGHAMIREVVKKGWVSWFWDRFVLPWCDMETFAKGLLVSVLLIRQGQILRFVPFEGRGGRVPWARKVVV
What is the function of this protein?
Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of sordarial, a salicylic aldehyde structurally related to the phytotoxin pyriculol (PubMed:19277664, PubMed:28485098, PubMed:30908040).  The most interesting aspect of this pathway is formation of an aromatic product from the highly reducing polyketide synthase srdA (PubMed:30908040).  SrdA synthesizes a reduced polyketide chain from one molecule of acetyl-CoA and five molecules of malonyl-CoA (PubMed:30908040).  The polyketide chain is then reductively released as an aldehyde (PubMed:30908040).  The oxidoreductases srdC, srdD and srdE then oxidize one of the hydroxy groups to facilitate the intramolecular aldol condensation, followed by dehydration to yield a salicylic aldehyde (PubMed:30908040).  This aldehyde can undergo facile reduction by endogenous reductases to yield the alcohol 1-hydroxy-2-hydroxymethyl-3-pent-1,3-dienylbenzene (PubMed:30908040).  The flavin-dependent srdI counteract against the propensity of the aldehydes to be reduced under physiological conditions and is responsible for reoxidizing 1-hydroxy-2-hydroxymethyl-3-pent-1,3-dienylbenzene back to the salicylic aldehyde (PubMed:30908040).  This salicylic aldehyde is then selectively epoxidized by the cupin-domain-containing oxidoreductase srdB to yield the epoxide, which can be hydrolyzed stereoselectively by the hydrolase srdG to give the final product sordarial (PubMed:30908040).
What are the official names of this protein?
FAD-dependent monooxygenase srdH, Fruiting body maturation protein 1, Sordarial biosynthesis cluster protein srdH.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: MATK_MARSC
Sequence: MEEKKDPRYLDLVISRKNDLLYPLIFQEYIYTLVHDHNLFPTILLENLGYDKRFRFLIVKRLITQMYQQNHLSLSAANLKQNPYFLYNKVLYSQKISEGLSIIVEIPFSLQLETSFKNLELVRVQNLKSIHSIFPFLEDKFPYLNLVSDGLFSYPIHLEKLVQILRYWLKDPASLHFLRLFFHEYWNWSHPSFEKKNLISFEKRNLRLFVFLYNSYVYEYESILFFIRRQFFHLPSKPFRFFFERLYFYVKIENLTEVFSKGSPVTLELFKEPNIHYIRYQGKFFFAYKGMPLLMNKWKYYFVTLFQNHFDVWFQTDKIHINPLYKHSFHCVGYLLSLKWNPSVIRSQMLQNAFIIENTMKKMDILVPIILMIDSLSKMKFCNKIGHPVSKPTWTDLLDSDIIDRFVRLCNKISYFYSGSSKKKNLYQIHYILRFACLKPLARKPKSSVRAFFKKLGSSFLEELFLEXQISSLIFIRSSPRSSDRSNQSKVRFWYLDIISINEIINHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: G3P1_ECO57
Sequence: MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLTDETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase A, GAPDH-A, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLA2_BACAN
Sequence: MTVQTAQIVKNYIGGEWVESISTKMEAVYNPATGEVIAQVPLSTKVDVEQAVLAANEAFKSWSKTAVPRRARILFKYQQLLVDNWEELAKLITIENGKSYNEAYGEVLRGIECVEFAAGAPTLMMGKQLPDIATGIESGMYRYPIGVIGGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPLLAARLAELAEEAGLPKGVLNIVNGAHDVVNGLLEHKLVKAISFVGSQPVAEYVYKKGTENLKRVQALAGAKNHSIVLNDANLELATKQIISAAFGSAGERCMAASVVTVEEEIADQLVERLVAEANKIVIGNGLDEDVFLGPVIRDNHKERTIGYIDSGVEQGATLVRDGREDTAVKGAGYFVGPTIFDHVTKEMKIWQDEIFAPVLSIVRVKSLDEAIEIANESRFANGACIYTDSGASVRQFRETIESGMLGVNVGVPAPMAFFPFSGWKDSFYGDLHANGTDGVEFYTRKKMLTSRWEK
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase 2, MSA dehydrogenase 2, Methylmalonate-semialdehyde dehydrogenase 2, MMSA dehydrogenase 2, MSDH 2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: RF1_AZOSB
Sequence: MKQSIRDKLEHLAGRLAELDRELSSEDATRDMNAFRDLSRERAELEPVVALYGAYRQAEQDCATARELLDDPEMQELGRSELEAGEARIAALDGDLQRALLPRDPNDERNLFLEIRAGTGGDEAALFAGDLLRMYSRYAERQRWRVEIVSSNPSDLGGYKEVIARIVGAGAYSRLKFESGGHRVQRIPVTETQGRIHTSACTVAVMPEADELAAVEINPADLRIDTFRASGAGGQHINKTDSAVRITHLPTGLVVECQDDRSQHRNKAQAMAVLAARLNDAQLRARQSAEAATRRSLIGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDAVMQGELDELLAALVLEHQAEQLAALAEEGL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIM15_XENLA
Sequence: MIDTLKGWAEYLVEWAAKDPYGFLITVLLALTPLFLASAVLSWKMAKMIEAKERDQKKKQKRQENIAKAKRTKKD
What are the official names of this protein?
Small integral membrane protein 15.
What is the protein family that this protein belongs to?
Belongs to the SMIM15 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HLDD_SHIB3
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLDIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: ARLY_CHLAA
Sequence: MEHRLWGGRFSEPTAAEMRRFNDSFHFDVRLAEVDIAGSIAWAGALLQAGLINETEHADLVRGLELVRAEFANGSFVAAAGDEDIHTAVERRLRELIGDAALKLHTGRSRNDQVATDMRLYTIGIARQLDRRLRDLQLALLAQAEQHTATVMPGYTHLQRAQPITFGHWCLAYVEMFARDRSRLNDAIRRMRVLPLGAGALAGNSLGVERERLTELLDEFDELSANSLDAVSDRDFVAEVLFACALIGVHLSRLAEDVILYASAEFGFLELADAYSTGSSLMPQKKNPDSMELLRGKSGRLLGNLVALLTVLKGLPLTYNKDMQEDKEPLFDSFDTLDLGLQVAAAAIATMTVRPERMAAALDDAMLATDLADELVRRGVPFRVAHSKVGQLVQRALTRGVSLRQLPLADYQAVEPSLDASIYDVFDMQRSVAQKASYGGTAPQRVREQCARWRDSLLNDE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCAR_SALPC
Sequence: MDHRLLEIIACPVCNGKLWYNQEQQELICKLDNLAFPLRDGIPVLLENEARALTSDESKS
What are the official names of this protein?
UPF0434 protein YcaR.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: CXAT1_CONCE
Sequence: MPKLEMMLLVLLIFPLSYFIAAGGQVVQVDRRGDGLAGYLQRGDRDVQDCQVSTPGSKWGRCCLNRVCGPMCCPASHCYCVYHRGRGHGCSC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Cp20.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2549_METMA
Sequence: MYFLKIRSELDSKFEKLAKKNKKQLEIILAKADEILENPHRYKNLKAPMNHLKRVHIDKHFVLVFSIDEESRSVTLEDYDHHDKIY
What are the official names of this protein?
Uncharacterized protein MM_2549.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1173.
Protein: SPEH_EXIS2
Sequence: MDTMGRHIIAELWDCNPEKLNDMEYVERLFVDAALQAGAEVREVAFHKFAPHGVSGVVIISESHLTIHSFPEHGYASVDVFTCGDRIDPAIAAHYIADGLDAKIRENVEIPRGMGPVEVPAATVQHVN
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: TRUB_PSYA2
Sequence: MSIASTQADKKSSNHPDKIKISGVILVDKPQGMTSQQVVSKVKYLFKSPNHDSKKAGHTGTLDPMATGLLPICLGEATKFSHYQLDADKSYQATILLGSQTDTGDADGQVTAEATISAFDDTMLDKIAQQFLGAQQQIPPMYSALKKDGKKLYEYARAGIEVDRPPRDIILKAIELKAIDEQQIQLTVTCSKGTYVRVLAEDIAKAIGTLGHLTALSRLQVGDFKIDETITLANLEALALEQRQTYLLPVDACIDINAELTLSSEQCERVQMGQRLNVIDQLTNDLQSYITSAIEQHLSTSNKNAAVNQNVEDDNDDNDDNDDNDDNDDNDDNDDNDDNAQQLLHEIPVDIRLIDEHGTFIGLGAVSLNGRLQPKKLIQL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: EX7S_ECOLC
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_MYCTO
Sequence: MTESPTAGPGGVPRADDADSDVPRYRYTAELAARLERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDDKLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMVGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRRSFSTTDVDFYRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKLTAGERADVIDEYRLVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVFRKRLRQWMMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFSARAASDDGFEVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAASWPAGVNPLWTYGGGTPGEAIAAYRRAIAAKSDLERQESREKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVIAGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLESAGRGRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELPDVPDYSPVLFDPDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPGGVDLYVGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDARGSYVPAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICDAYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGETRVADGVELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTKKHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTTSLAHGPFPKADAAYLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGATPRKVIVVAGRLVNLVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFD_METMA
Sequence: MIIFSGGTGTPKLLDGLKEILPEEELTVVVNTAEDLWVSGNLISPDLDTVLYLFSDQIDRKRWWGIENDTFGTYERMKELGIEEGLKLGDRDRATHIIRSNIIRDGASLTDSTVKLSSLFGIKANILPMSDDPVSTYIETAEGIMHFQDFWIGKRGEPDVRGVDIRGVSEASISPKVLEAFEKEENILIGPSNPITSIGPIISLPGMRELLKKKKVVAVSPIIGNAPVSGPAGKLMPACGIEVSSMGVAEYYQDFLDVFVFDERDRADEFAFERLGCHASRADTLMTSTEKSKELAEIVVQAF
What is the function of this protein?
Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
What are the official names of this protein?
2-phospho-L-lactate transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: S4A10_RAT
Sequence: MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGGESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQSQKKLTNRIPIVRSFADIGKKQSEPNSMDKNGQVVSPQSAPACAENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRLDKGPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKTPSLPNGTAAHGGPEQHGGHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSESYPINMHNDLELLTQYSCNCMEPHSPSNDTLKEWRESNISASDIIWGNLTVSECRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEMSKTAMWGNLLVTADNSKEKESRFPSKSSPS
What is the function of this protein?
Sodium/bicarbonate cotransporter which mediates cotransport of sodium and bicarbonate in association with an efflux of intracellular chloride and is involved in NaCl absorption in the small intestine.
What are the official names of this protein?
Sodium-driven chloride bicarbonate exchanger, Solute carrier family 4 member 10.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon. Perikaryon. Presynapse. Postsynapse. Note=Detected in dendrites and axon terminals of retinal OFF bipolar cells and in axon terminals of ON bipolar cells. In amacrine cells, located in the perikaryon. Also detected in basal and apical dendrites of hippocampal pyramidal cells (By similarity). In the kidney, isoforms starting with Met-Glu-Ile-Lys localize predominantly to the basolateral membrane of renal thick ascending limbs and inner medullary collecting ducts while isoforms starting with Met-Cys-Asp-Leu localize to the apical membrane of proximal tubules (PubMed:28280139).
Protein: HYES_MOUSE
Sequence: MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITFSQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTEVQNPSVTSKI
What is the function of this protein?
Bifunctional enzyme.  The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid (By similarity).  Has phosphatase activity toward lyso-glycerophospholipids with also some lower activity toward lysolipids of sphingolipid and isoprenoid phosphates (By similarity).
What are the official names of this protein?
Bifunctional epoxide hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome.
Protein: PDXS_MYCBO
Sequence: MDPAGNPATGTARVKRGMAEMLKGGVIMDVVTPEQARIAEGAGAVAVMALERVPADIRAQGGVSRMSDPDMIEGIIAAVTIPVMAKVRIGHFVEAQILQTLGVDYIDESEVLTPADYAHHIDKWNFTVPFVCGATNLGEALRRISEGAAMIRSKGEAGTGDVSNATTHMRAIGGEIRRLTSMSEDELFVAAKELQAPYELVAEVARAGKLPVTLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGAPEHRAAAIVKATTFFDDPDVLAKVSRGLGEAMVGINVDEIAVGHRLAQRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: MATK_QUEGE
Sequence: MEEFQGYLELDRFRQHDFLYPLIFREYSYALAHGHGLNRYMLLENIGYDNKSSLLIVKRLITTMYHQNYLIISANDSKQNPFFGYNKNLHSKILSEGFAIIVEIPFYLRLISSLEGAEIVRFYNLRSIHSIFPFLEEKFPHLNYSADILIPYPAHLEILVQTLRYRVKDASYLHLLRFFLHEYSNCNSLIITNKSISIFSKSNPRFFLFLYNSYICEYESIFLFLRNQSSHLRLTSSGVLFERLCLYRKIEHFAEVFANDFPVIPCFLKDPFMHYVRYQGKSILASKDTPLLMNKWKSYLVNLWQCHFDVWSHAASIRINQLSKHSLDFLSYFSSVRRNPAVVRNQMLENSFLLNNAPNKLDTIVPIIPLIGSLAKAKFCNAVGHPISKLTRADLSDFEIINRFLHICRNLSHYYSGSSKKKNMYRIKYILRLSCVKTLARKHKSTARAFLKRVDSEFFQEFFTEEGGFISLIFPRASFALRRLYSGRVWYLDIIFINGLSNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RIMP_NITMU
Sequence: MDLYELLEPTLAGLGYELVDLERSPGGKLLRIFIDKPGGVNVDDCVTVSNHLSRFLAVENVDYDRLEVSSPGLDRPLKKTADFIRFAGESVKLRLRVALQGQRNFVGILREVKDGILKLEVDGKMLDLELTNLEKVRLVPKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_CHLT3
Sequence: MKVNVDMNSGFCFGVQFAIDRVEDEMKASGPLYSLGDIVHNAVEVERLEKLGLKTITIEEFKTLKNTRVFIRAHGEPPSTYKLALENNIELIDATCPVVMKLQQRIKEFYDRGYQVLIYGREGHPEVIGLCGQCNNEAIVLKHADLSDRGETEKIDFSRKTVLFSQTTKDTTGFYELKANLENVFREHHAAQNFDSAATESIVPDFQAKDTICRQVSNRDQKLAAFSKENECVIFVAGRKSSNGKVLFEVCKDANSNTHFIENQSELERAWFLRPDDSLVESVGVCGATSTPMWVMQQVAEHIRATFAAERFVQS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: SYL_METM5
Sequence: MDQNGVNEGTGHKSVDLIQIMDKWQKKWTEAKIFEAEHDLRDKFFITAAFPYLNGVLHAGHLRTFTIPETIARYQRMKNKNVLWTFGFHVTGTPILGLANQIKDRKEDIIWAYNNLHNIPMDELLKLKTPEAIVECFSKKATEAFKRMGFSLDWRRNFKTDDKVFSKFIEWQFYKLKEMGHITKGSHPVRYCPKCENPVEDHDLLHGEESTTVEYSLIKFTSEFDGKEIIMPMATLRPETLFGVTNAWVNPNEIYVMAKVHDEIQKLDGEDVELKYNGIWIVGKECADKLKEQDRKIEILKEIKGNELLGLKIKNPVTKKEVPLLPADFVEMGIGTGWVMSVPAHAPYDYVALRDLGKIEEVGLIPLIEIEGYDKYPAKEIVEKLGVKDQNDDELLEQATSKIYKDEFHKGKLNENCGEYAGISVKDIKEKLTKDYLNSNIAEIMYEFSEQKVVCRCGEKCIIKTVKGQWFINYSDENWKKLAHECIDNMNFAPENIRQEFHNKVDWMKDKACARKKGLGTILPFDENWIIESLSDSTIYMAYYTIARFINEGLTPEQLIPELFEYVYLGNGNVEEITKNSNISKETIEEMRKEFLYYYPLDWRCSAKDLIPNHLTFMIFNHVALFGREHWPRGIEINGYVTIEGKKLSKSKGPVLPVSEVAENFGADVARFYITTCAELPQDADVKFKEMEKARDNLIKLYELAVSVMEEEKTEKELSLIDKWLLHKTYSSINGAETAYEEFQLRKIGLMFYELINDLRWYKRRGGENNNVLKEVVEIWTKLLSPVTPHLCEEIWEKLGYAGFISQELYPEIKLEMVNEDLELGEEFIKSAMEDIRNINGVAKINPEKMYLYTADDWKYDLLEFMNENSEKNVKALIPMVMKEDKFKRHGKEVMKLINEIMKIGVKKAIAEVEILENAKTFIESEFDCEVIVNGEDVKGKKKFAIPYKPAIYME
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_FLAPJ
Sequence: MRHGKKFNHLSRQKGHRAAMLANMACSLIEHKRINTTVAKAKALKQFVEPLITKSKDDTTHNRRICFAYLRSKYAVTDLFRDVAAKVGDRPGGYTRIIKLGNRLGDNADMAMIELVDFNELYNGGKKEEVKTKSRRGGKAKKAEPTTEAPANTTEETTDSAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: NUOK_PSEF5
Sequence: MPTISLGTIPMEHGLAVAGILFCLGLVGLMVRRNILFVLMSLEVMMNASALAFIVAGARWAQPDGQVMFILVISLAAAEASIGLAILLQLYRRFHTLDIDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL7_SALEP
Sequence: MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKSLEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.