PharMolix/UniProtQA huggingface dataset:
Protein: CP19A_HORSE
Sequence: MILEMLNPMHYNLTSMVPEVMPVATLPILLLTGFLFFVWNHEETSSIPGPGYCMGIGPLISHLRFLWMGLGSACNYYNKMYGEFVRVWISGEETLVISKSSSTFHIMKHDHYSSRFGSTFGLQYMGMHENGVIFNNNPAVWKALRPFFVKALSGPSLARMVTVCVESVNNHLDRLDEVTNALGHVNVLTLMRRTMLDASNTLFLRIPLDEKNIVLKIQGYFDAWQALLIKPNIFFKISWLSRKHQKSIKELRDAVGILAEEKRHRIFTAEKLEDHVDFATDLILAEKRGELTKENVNQCILEMMIAAPDTLSVTVFFMLCLIAQHPKVEEALMKEIQTVLGERDLKNDDMQKLKVMENFINESMRYQPVVDIVMRKALEDDVIDGYPVKKGTNIILNIGRMHKLEFFPKPNEFTLENFEKNVPYRYFQPFGFGPRSCAGKFIAMVMMKVMLVSLLRRFHVKTLQGNCLENMQKTNDLALHPDESRSLPAMIFTPRNSEKCLEH
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrogens, estrone and estradiol, respectively.  Catalyzes three successive oxidations of C19 androgens: two conventional oxidations at C19 yielding 19-hydroxy and 19-oxo/19-aldehyde derivatives, followed by a third oxidative aromatization step that involves C1-beta hydrogen abstraction combined with cleavage of the C10-C19 bond to yield a phenolic A ring and formic acid.  Alternatively, the third oxidative reaction yields a 19-norsteroid and formic acid.  Converts dihydrotestosterone to delta1,10-dehydro 19-nordihydrotestosterone and may play a role in homeostasis of this potent androgen.  Also displays 2-hydroxylase activity toward estrone.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 17-alpha, Cytochrome P450 19A1, Estrogen synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Protein: PANC_VIBC3
Sequence: MQVFADIAVLREQIKQIKREGRRVAFVPTMGNLHEGHLTLVRKARELADVVVVSIFVNPMQFDRAEDLKNYPRTLEEDLSKLNGEGVDLVLTPTPETMYPQGLDKQTFVEVPGLSYMLEGASRPGHFRGVATIVTKLFNIVQPDVACFGEKDFQQLAVIRQMVEDLCMDIEIVGVATVRELDGLAMSSRNNLLTLDERQRAPVLARTMRWISSAIRGGRDDYPSIIEDAVDQLRAADLEPDEIFIRDARTLLPISSESKQAVILMSAFLGKVRLIDNQVLDLQTDTKASSEEE
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM11_KOMPG
Sequence: MRILLIFFVPSGILDQLFPRISILSTLRVNLTNSPLLTPNLTLYSMVNGFDFSKMFGRKDPELVSKEVKQYNERRFKQMALFYGFTVATFICSKIAYRGVIKRRYVPNYYQHNHVAPPFSFYRDALSAVFHSTSLAITSLGMASTGVLWYYDISSVAEFSFKLKQALGGHDKEQELKKLPEDETVQEIQNSINSYLGDR
What are the official names of this protein?
Altered inheritance of mitochondria protein 11.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: F217B_HUMAN
Sequence: MNAGPSWNKVQHSKNSSGKRQSKSQVPHASSQPRSSLTAVTQPTEEKLKESISPEARRKRNPLGSRCQGASGNKLFLDFQSMKIIKENADEDSASDLSDSERIPIPPSPLTPPDLNLRAEEIDPVYFDLHPGQGHTKPEYYYPNFLPSPFSSWDLRDMALLLNAENKTEAVPRVGGLLGKYIDRLIQLEWLQVQTVQCEKAKGGKARPPTAPGTSGALKSPGRSKLIASALSKPLPHQEGASKSGPSRKKAFHHEEIHPSHYAFETSPRPIDVLGGTRFCSQRQTLEMRTEEKKKKSSKSTKLQRWDLSGSGSSSKVETSGHIRVPKQAAVILDSADSCKASKTQAHAHPRKKGKAESCGHATVSSEKKLKTNGVKQNTYKLK
What are the official names of this protein?
Protein FAM217B.
What is the protein family that this protein belongs to?
Belongs to the FAM217 family.
Protein: REPA_ECOLX
Sequence: METQLVISDVLFGNTEEKQKPLTVNELNTIQPVAFMRLGLFVPKPSRSSDYSPMIDVSELSSTFEFARLEGFTDIKITGERLDMDTDFKVWIGIVKAFSKYGISSNRIKLKFSEFAKDCGFPGKKLDKKLRAHIDESLRKIRGKSISFKRGKDSQSAYHTGLIKIAYFNADTDVVELEADERLWELYYFDYRVVLQLHAIKALPRLEVAQALYTFLASLPSNPAPISFERLRERLSLISQVKEQNRIIKKAITKLIDIGNLDASMVKKGQENYLIIHKRSPKLSVINE
What is the function of this protein?
This protein is essential for plasmid replication; it is involved in copy control functions.
What are the official names of this protein?
Protein RepA.
What is the protein family that this protein belongs to?
Belongs to the initiator RepB protein family.
Protein: MSRB_PHOLL
Sequence: MAKHPEVSLYKELTDIQRHVTQNAGTEPPFSGKLLHNKKSGVYHCLCCEQPLFMSGTKFDSGCGWPSFYQPATHDAVQYLDDDSHNMHRIEVRCGHCNAHLGHVFPDGPQPTGERFCINSAALSFTDENTGEKTVG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: GIP3_YEAST
Sequence: MITNTEFDVPVDWLYKGKSRRKTNTKPSRPSTSPASSSSTSSSKNGDNSTSGNRSSNDKPRARSSSVSNAALCNTEKPDLKRNDGNTSASDTDNIPLLTPINSGNRSDSADIDNPATVDAIDLIDNDDNGSSTQFVRKKRSTSISNAVVSSKPRLASSAINATASSSVGKGKHPPISSPSNATLKRSNSTSGEKTKRSIFGSLFSKRSTSSSASTAKKPLPVVNTSTTENESGGIKAVATPDPRVKEISSPMRGVAPTASKPQTPILPSPALAVKDLSTVSLKRVSFAVDKFESDPPQQLPSRTPKKGNILIPDDMISEVPSISVGISSSNQSAKSTNSNIKGPLYTKKSKEYILALENQKLALREAAKHQQEAHFAANRIAFEVANFKTASDAGGKLTEKSSEGTITKQREEVSPPNVEADRELENNKLAENLSKAGIDKPIHMHEHYFKEPDQDKYQDGHSIENNEVTLDVIYTRCCHLREILPIPSTLRQVKDKTAPLQILKFLNPKPTLIDILSFCDFITIAPIHTIVFDNVALNQDMFRIIISALVNSTVLDKLSLRNVRIDQDGWKLLCKFLLLNKSLNKLDISQTKIKSDLAESLYRHNMDWNLFTDVLSQRSHKPIEELLFNGIQFSKIPYSCFARLLTSFATQKNFPESGIRLGLAGATTSNISQDCLKFIFNWMSQYNVQGVDLAFNDLSTMIKPMVGKLSALSYDNLRYFILNSTNISTSYDLALLLKYLSKLPNLIFLDLSNLSQCFPDILPYMYKYLPRFPNLKRIHLDSNNLTLKELAVVCNILIKCKSLSHVSMTNQNVENFYLMNGTDSPVQQTNTDGDLDSSSTLDVKGQFAKNSFSSTLYAFARDSPNLIGLDFDYDLISEEIQSRIALCLMRNMKRTMDSTFQLDELDSQDDLLFDGSLVTMTAESVLEKLNLLSDKSTKVKKDTTKRYLLKKYIEKFHILHHNVQHTIDTMFEKRKSGELPLQEKENLVRLLLLEQNLCNILELFSHNPNLNDVLGSSRDDSKESVDSSEDSKLPALKHVESGYHVPEEKIQPENDVITARPHLMATDSGKTIDVFTGKPLVFKHTSSSTSVGCKKQEEEEGELHKWGFFVQQQRSLYPENESTRQTPFASGDTPINTETAGKSTSSPSVSTSNNETATTSLFSPANPKILPKIPSGAVLRSAIMKAKGIDSIDDLIQNVNSNNIELENIYGESIQNSASTFTPGVDSDVSAPNTDKGSVETLPAVSTDDPNCEVKVTATYDKLLNNLSMERSIRL
What are the official names of this protein?
GLC7-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the GIP3/HER1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: MIAB_SHIBS
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGSTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEA_KLULA
Sequence: MVSVKASAAEKKEFLQSQIDEIEKWWSEPRWKDTKRIYSAYEIAKRRGSVKPNTFPSTVMSQKLFKILGEHAKNGTVSKTFGALDPVQVTQMSKYLDTIYVSGWQCSSTASTSNEPGPDLADYPMDTVPNKVEHLFKAQQFHDRKQWERICDGTIEESEIIDYLTPIVADGDAGHGGLTAVFKLTKMFIERGAAGIHIEDQTSTNKKCGHMAGRCVIPVQEHINRLITCRMAADVLGSDLILVARTDSEAATLLSSTADSRDHYFILGASNPAVKGKPLNDLLNKAILDGATIDDLQTIEKEWLAKADVKLFHEVFADAAKAAGKDQSVIDQFNSKVNPLSETSIYEMQALAKELLGTELFFDWDLPRGREGLYRYQGGTQCSVMRARAFAPYADLCWMESNYPDYEQAKEFAEGVTAKFPGKWMAYNLSPSFNWTKAMSVDEQETFIQRLGDLGYIWQFITLAGLHTSGLAIEQFSKNFAKLGMKAYAQDIQKKELDNGIDMVKHQKWSGAEYIDGLLRLAQGGLAATAAMGQGVTEDQFK
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: SSK_DROME
Sequence: MVSVETVGSIFIKALKLIINLVIIFLYRWGDGGEFLGIGGTWNLNEEKSADAEIVASGVMVGFLIYTGCHTIAFAFGTTKHKGELCDTIMNVVGCIMWIAVGGVALHYWKGYMSDEGFLYVNSERQVGIAMGSLCVIEGALYLLDTVLACIHYSKGDTDYTQ
What is the function of this protein?
Required for assembly of smooth septate junctions (sSJs), together with mesh and Tsp2A (PubMed:22854041, PubMed:26848177).  May be important for barrier function of the midgut epithelium.
What are the official names of this protein?
Protein snakeskin.
What are the subcellular locations of this protein?
Apicolateral cell membrane; Multi-pass membrane protein. Cell junction, septate junction. Note=Specific to smooth septate junctions.
Protein: EST1A_PONAB
Sequence: MAEGLERVRISASELRGILATLAPQAGSRENMKELKEARPRKDNRRPDLEIYKPGLSRLRNKPKIKEPSGSEEFKDEIVNDRDCSAVENGTQPFKDVCKELNNQQQNGPIDPENNRGQESFPRTAGQEDRSLKMIKRTKKPDLQIYQPGRRLQTVSKESASRVEEEEILNQVEQLRVEEDECRGNVVKEEVVNKPDRAEIEKSPGGDRVRAAKGEKGKRIEKGEGMRKTNDDPAQGKPGSAKRYSRSDKRRNRYRTCSTSSAGSNNSAEGAGLTDNGCRRRRQDRTKERPRLKKQVSVSSTDSLDEDRIDEPDGLEPRRSSERKKHLERNWSGRGEGEQKSNGKENRGTLRVTFDAEAMNKESPMVRSARDDMDRGKPDKGLSSGGKGSEKQESKNPKQELRGRGRGILILPAHTTLSVNSAGSPESAPLGPRLLFGSGSKGPRSWGRGGTTRRLWDPNNPDQKPALKTQTPQLHFLDTDDEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQYPVGPTNGVYPGPYYPGYPTPSGPYVCSPLPASTMSPEEVEQHMRNLQQQELHRLLRVADNQELQLSNLLSRDRISPEGLEKMAQLRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVKDPNVENPEQIRNRLLELLDEGSDFFDSLLQKLQVTYKFKLEDYIDGLAIRSKPLRKTVKYALISAQRCMICQGDIARYREQARDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTRRKLDAVYYYMRSLAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFELSPDQWRKGKKSTFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGSLSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAAALGLAMFSLLVCRCTYLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLADFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQEEPLLAFKDGKYVSVAPAPDTMGKEMVSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELEIRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRGNELESIAFRSEDITGQLGNNDDLILSCCLHYCKDKAKDFMPTSKEEPIRLLREVVLLTDDRNLRVKALTRNVPVRDIPAFLTWAQVG
What is the function of this protein?
Plays a role in nonsense-mediated mRNA decay.  Is thought to provide a link to the mRNA degradation machinery as it has endonuclease activity required to initiate NMD, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.  Degrades single-stranded RNA (ssRNA), but not ssDNA or dsRNA.
What are the official names of this protein?
Telomerase-binding protein EST1A, Ever shorter telomeres 1A, Nonsense mediated mRNA decay factor SMG6, Smg-6 homolog.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome, telomere. Cytoplasm, cytosol. Note=Particularly enriched in the nucleolus.
Protein: RISB_HELP2
Sequence: MRIIEGKLQLQGNEKVAILTSRFNHIITDRLKEGAMDCFKRHGGDEDLLDIVLVPGAYELPFILERLLGSGKYDGVCVLGAIIRGGTPHFDYVSAEATKGIAHAMLKYSMPVSFGVLTTDNIEQAIERAGSKAGNKGFEAMSTLIELLSLCQTLKG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: EFP_ZYMMO
Sequence: MKISGVDIRPGNILEYEGGLWRAAKIQHTQPGKGGAYMQVEMKNLIDGRKTNVRFRSAETVERVRLDTKDFQYLFADGDMLTFMDKETYEQISLPKDLLGDAVAFLQDGMDVVMELYEEKPISVQLPEQVEAEIVEADAVVKGQTASSSYKPAILDNGVRVMVPPHITAGTRIIVDVNTQEYVKRAD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLSA_PSEFS
Sequence: MDFFGPHLLAYFIATLHFLGTLAAIHAVLTVRTAQGSIAWALSLMFMPYLTLIPYLIFGRSTFDAYIQARRQANQEMHTAITALNWRPWVEEALAARNSSAYASLRAMPKLGRMPCLANNEVHLLINGDATFSAIFEAIRNARTAVLFQFFIIHDDELGRQLHALLKEKSAEGVAIYVLYDRIGSHALPHRYVQSLRDAGVQVKAFATRSGWLNRFQVNFRNHRKIVVVDGITGFVGGHNVGDEYLGKKPPLAPWRDTHVQVTGPVVACLQESFAEDWFWAARELPPLILPDAYPEDGVLCQLLASGPADPYETCSLFFVEAIHAATERVWITSPYFIPDEAVFAALRLAVLRGVDVRLLLPSRPDHRIVYAASSLYAIEAVRAGVRVFRYTPGFLHQKVVLVDSEISAIGSANMDNRSFRLNFEVMLLTVDEAFAKEVEHMLLDDFALAHEVSQEESRETRRLQQLGMRVARLISPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBF_DIOBU
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TRPA_LACCA
Sequence: MLMSKLADVFKNHKVFIPFIVADDPDFETTVKNVVALAKGGADIVELGIPFSDPVADGPVIQAADLRAFAANVRTKTVFDIVEAARKETAVPIVFLTYLNIVFKYGYDAFLKRCADLNVAGLVIPDLPYESRDEIVPIAEKYGIDIIPLITPTSGHRIEKIAKSASGFIYVVSSMGITGERDEFFAGLKALVAEIKQYTNVPTAIGFGIHTPEQAQTMAGIADGVIIGSAIVDLVAKEKQQAPAAIEKFTKQIRVAVDAKKQISVK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: MAK16_SCHPO
Sequence: MQQDEVIWQVVGHEFCSYRIKGEAQNFCRNEYNVTGLCNRQSCPLANSRYATVREDNGKLYLYMKTIERAHFPSKLWQRIKLSKNYAKALEQIDQQLLYWPGRQIHRCKQRLTRLTQYLLKARRLALKHQPALIPIKPKQAHREASRERKALIAAKLEKNIEKELVKRLKSGVYGDQPLNVNEEIWNKVLAAREGLIDEGEEEEEREEAELEFVSDDEDEEEISDLEDWLGSDQSMETSESEEEESSESESDEDEDEDNKGKIRKRKTDDAKKSRKKRAPHIHIEYEQERENEKIPAVQHSW
What are the official names of this protein?
Protein mak16.
What is the protein family that this protein belongs to?
Belongs to the MAK16 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MQO1_PSEPK
Sequence: MAQNESVDVVLVGAGIMSATLAVLLKELDPTLKLEVVEAMDSGAAESSNPWNNAGTGHAGLCELNYTPQAADGSIDIKKAVHINTQFEVSRQFWAYLTKKGNFGSARAFINPVPHLSYVEGDKGVSFLKKRFELLKQHHAFAEMEYTEDKAVMNDWMPLMMPGRPADQHIAATRVAKGTDVNFGALTNKLLKLLGDSPDAQVKYSKKVVGLRRNGSGWTVSIKDVNSGGSREVDARFVFLGAGGAALPLLQLSGIPESKGFGGFPVSGQWLRCDNPEIVKQHQAKVYSQAAVGAPPMSVPHLDTRVVDGKTSLLFGPYAGFTTKFLKHGSLMDLPLSVRMGNIGPMLAVARDNMDLTKYLVSEVMQSMEQRLEALRRFYPQAKAEDWRLEVAGQRVQIIKKDPKKGGVLQFGTELVSAQDGSLAALLGASPGASVTVSIMLELIERCFPEQAKGAWAAKLKEIFPAREKTLATDAALYHKISADNDAALDLAESSPAAKHYA
What are the official names of this protein?
Probable malate:quinone oxidoreductase 1, MQO 1, Malate dehydrogenase [quinone] 1.
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: HPPA2_RHILT
Sequence: AAIFFAGTPILESAMVYPLAICGACILTSIAGTFFVKLGTNNSIMGALYKGLIATGVFSVAGLAVATYATVGWGTIGTVAGMEITGTNLFFCGLVGLVVTALIVVITEYYTGTNKRPVNSIAQASVTGHGTNVIQGLAVSLESTALPAIVIVGGIIGTYQLGGLFGTGIAVTAMLGLAGMIVALDAFGPVTDNAGGIAEMAGLDPDVRKRPTRWM
What is the function of this protein?
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane.  Generates a proton motive force (By similarity).
What are the official names of this protein?
Pyrophosphate-energized proton pump 2, Membrane-bound proton-translocating pyrophosphatase 2, Pyrophosphate-energized inorganic pyrophosphatase 2, H(+)-PPase 2.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MED20_AEDAE
Sequence: MGVTILQPYPVENKSGAQTIEFLVKRVLALGAVQVGHFLVDCETYTSIPQIGATKTVHILHNSEQPASVFSILDTGTKQIPLVTDGLFDLLMTRISPVYTSKKQTKIESKGPRFEFGDFLIKLGSVTMSQNFKGVLVEVEYRPCLVASSCWELMREFLQGFLGSNVSNTIPAYFAQRININTNHTKANDVYQPIDTINQYLEHFTNYRKQTTPVVAPRV
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 20 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPPP1_CHRVO
Sequence: MLFHSLIMGLVEGITEFLPISSTGHLILTGDLLGFLDKEKRDVYEIFIQLGAMLAVVWEYRRKIGHTVAGAVRPGGERNLLLGIVIAFIPAAVAGLLFSKQIKAVLFNPVCVAIAFIVGGLIILWAEKREHKVAVETVDDLSLKDALKVGLCQCLALIPGTSRSGATIIGGLFLGLSRKAATEFSFFLGIPTLGAASLYSLIKHRDALSADDIGVFAVGFIASFVFAFLAIRALLRFISTHSFAVFAWYRIAFGLIVLGTWWSGLVNWSA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 1, Bacitracin resistance protein 1, Undecaprenyl pyrophosphate phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1861_PYRAE
Sequence: MDCNNLLNAARRGEAELLTRLLNEGCSPDVQDDYGRTPLYYAAERGDVGTVDLLIKAGADPNARDREGKTPIIIATQSRKFGVIPLLSASAVGVEEALYTAARNGCHKAVRYMLARGVRPGASHGESLLHLVAGDAGLVKLLLEYGVDPNARDAHGKTPLHMASEHNCAQCVELLLKRGPDVNVKDGAGRTPLHYADDVDCIKLLLRYGADLNAVDNMGRTPLHYAEDGLAAEALLKRGARPVPDKYGELPTIPTC
What are the official names of this protein?
Putative ankyrin repeat protein PAE1861.
Protein: QSEE_ECO57
Sequence: MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQAALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHAGVLPDDKLYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELDNVELAPLVETVVSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPSSKNTK
What is the function of this protein?
Member of the two-component regulatory system QseF/QseE involved in the regulation of virulence and metabolism in EHEC.  Required for pedestal formation in host epithelial cells during infection.  Autophosphorylates in response to epinephrine, sulfate or phosphate and then probably transfers its phosphate group to QseF.
What are the official names of this protein?
Sensor histidine kinase QseE, Quorum-sensing regulator protein E.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVA_HERAR
Sequence: MIGRLSGVLLEKNPPQLLVDCNGVGYEVNVPMSTFYNLPGLGEKVALLTHLTVREDAHILFGFGTAEERNVFKQLVKITGIGARTALSILSGMSVADLSNAITLQEAGRLTKIPGIGKKTAERLLLELKGKLGADLGAAGGVIHSDATSDILNALLALGYSDKEALLAMKQVPAGTGVSDGIKLALKALSKA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PEPB_VIBC1
Sequence: MSTQMSVFLSQEPAAPHWGDKALLSFAENGATIHLGDGHDLGAIQRAARQLDGQGIRSILLAGDNWDLESIWAFHQGYRNPKKHGTLEWVALSEQDQAELHARITSTDFTRDIINKTAEEVAPRQLATMAAEFIKSIAPQGTVTARIVKDKDLLSEGWEGIYAVGRGSERTSAMLQLDYNPTGDENAPVFACLVGKGITFDSGGYSLKPSNFMTAMKADMGGSGTITGGLGLAILRGLNKRVKLILCCAENMVSGRALKLGDIITYKNGKTVEIMNTDAEGRLVLADGLIYASEQNPELIIDCATLTGAAKNALGNDYHALMSFDDELSHQALTAANQEKEGLWPLPLADFHRGMLPSNFADLSNISSGDYSPGASTAAAFLSYFVEDYKKGWLHFDCAGTYRKSASDKWAAGATGMGVRTLARFLNEQAAK
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MKCE_DICDI
Sequence: MQKIVSFLKKKKEPNSWSNFDRSDDKSKSLSKKGSLYANGNYDGGGSGSGSGGSSSNSSGSSRKINTGGNNRNGGGMVHSPSNSSISSTSSNNSNSTTASSSSKLKGNKNRNSSGKQKNSSSQHQQYGNTYYLDDECDSDDFIPGEVRSISKTIDFSKSERKWLTSLNIPQELLDGNINVLLNVLNFLSKKEGILYIQTPTNIINNTGKKNFQQQQLQQLQQQQQQQQLQQQQHQQHNHQIYGNGNNNNLNVNVNVNGNNNNSNNNNGNYTSYVNSRSNSIASNNSSITPSTSCSNLNNDNNNNNNNNCTDNNSNNNNNNNNNNSTTTTTTITNTNVNMIGASNINSSKSNLNSLLLSGGSNGNGGVDNLSSTTTSLSQNPPIQPMRRSDYNRIFIEPGKFYIFPESESFALARLVVEEEDPSKLFRIGENAEVKGAFGTVYQVFYVNGQYNNVDVALKKMDHKSEKKRRNNLNEISILRYLKHPNIVTYINSYEKNDEEIWMVMEYMDGGTIRDAISNFTFTEKYVAYITKEILHSLEYLASLNIAHRDLKSSNIMINSKAEVKLIDFGFSIDLTHLKQDINMCGSPFYMSPEQIQDKAHGLAVDIWSLGIVVAEMVRGRVPHHKSKIKAMFLAGTVGVKFSKEKKYSCHWSPELFDFLNVCLQMDPTKRPTPTQLLQHPFIATAATKAETLDLLPLLFMSKTLSKLSRGRDNQ
What are the official names of this protein?
Probable serine/threonine-protein kinase mkcE, MAP kinase cascade E.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.