PharMolix/UniProtQA huggingface dataset:
Protein: SYY_HALMA
Sequence: MDTAERLDLVTRHTTEVVTEDELRTLFEESDPSAYIGYAPTGEMHIGHFTTMRKLADFLRAGVDVTVLIADLHAHLDDNKSPFDLLDARSAYYETAIEGMIEAAGADPEDVTFVRGTDFQLDEEYTLEMYRMAAETTISRTQRAASEVVRESESPNLGGLIYPLMQTLDVKALDADIAYGGVDQRGIYMLSREILPDHGGESPICLFAPLLSGLSGGKMSASDEASKVNLTDSPDEVDEKINQAYCPAGEVEENGVLEYLQHLVFPVLDVRGDSFVVERPEEYGGDLTYESYDEVESDFVSGELHPADLKPSAASAISDVIDPVRERLADKDELLAEAYPEKYGAE
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAO3_BACSU
Sequence: MKQFRVTNEGDIQTTLRGLEVLSVPFLNKGVAFTEEERKELGLKGFLPPKVLTIDDQAKRAYEQYSAQPDDLSKNVYLTALHDRNETLFYRLLNDHLGEMLPIVYTPTVGTAIQRYSHEYRKPRGLYLSIDDPDGMKEAFKQYKDQSDTIDLIVATDAEGILGIGDWGVGGIAISIGKLAVYTAAAGIDPSRVLAVVLDAGTNQESLLNDPLYVGNQHSRVRGERYDQFIDDYVALARETFPNALLHWEDFGAKNARSILKRYKDKVCTFNDDIQGTGAVSLAAVLSCAKASKVPLRDHRVVIFGAGTAGIGIAEQLREALVREGLSEEESYKRFWCIDRNGLLTDDMDQLLDFQKPYARSADEVKDYQRNGDGGGIDLLEVVRQAKPTILIGTSTVSGAFTEEIVKEMASHVKRPAILPMSNPTTLSEAKPEDLIEWTEGRALITTGSPFPPVEYNGVTYHIGQANNALVFPGLGLGTIVTKSKLITDGMFEACARAIAGMVNVGVPGAPMLPKVEDLRTVSATVAVEVAKTAMKEGVATEEPEDIIQAVQDAMWYPVYKPIRAI
What is the function of this protein?
Catalyzes the decarboxylation of malate to pyruvate.  Can use NAD and NADP, but with a strong preference for NAD.  Can also catalyze the decarboxylation of oxaloacetate (PubMed:16788182).  Involved in keeping the ATP levels high (PubMed:23136871).
What are the official names of this protein?
NAD-dependent malic enzyme 3, NAD-ME 3, Malate dehydrogenase MalS.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: RAPZ_ECO24
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: APCD_SYNP6
Sequence: MTIVSQVILKADDELRYPSGGELKNITDFFKTGEQRLRIAQVLSDSEKKIVDQASRKLWQRRPDFIAPGGNAYGQRQRAQCLRDYGWYLRLITYGVLAGDKEPIESIGLLGAREMYNSLGVPLPGMAEAIRTLKEASLALLSSADATVAAPYFDFLIQGMETI
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin alpha-B chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
Protein: ATPB_SOLUE
Sequence: MVTTNVVTGKVVVVSGPAVDCEFPEGQIPPVHTAIRIISEGFDIPTPIDIICEVQQHIGEGRVRTIALQPTEGLVRGMQAISLGHPVEVPVGPETLGRVLNVIGEPVDEMGPVNAKKHYPIHRPAPSFEDQSTRLEMFETGIKVIDLIEPYLRGGKIGLFGGAGVGKTVIIQELINNLAMKHGGVSVFAGVGERTREGNDLWLEFQESGVIDPHDYTKSKCALIYGQMTEPPGARLRVGLTGLTVAEYFRDEEHQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPNLATEMGELQERITSTKNGSITSVQAIYVPADDYTDPAPATAFAHLDATTNLSRDIAALGIYPAVDPLASTSRILDPHIVGEDHYATAQMVKGTLQRYKDLQDIIAILGIDELSDEDKLTVARARKVQKFLSQPFHVAEQFTGFKGKYVKLADSIKGFREIVEGKHDGVPEQAFYMQGTIEDVLEKAEAMKKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HEM3_OCEIH
Sequence: MRKIIVGTRKSNLALTQTEWVIDQLKKAGVKNEFEIKKIVTKGDQILDVTLSKVGGKGLFVKEIEKAMFDKEIDLAVHSMKDMPAVIPEGLTISSIPEREDHRDAYLAKDNILLQDLPEGAIVGTSSLRRGAQILAERPDLTIKWIRGNIETRIRKLQEEDYDAIILAVSGLKRVGLSEELITEYLEPEVCVPAVGQGALAIESREDDEELTNIVKKIHDAYTAKTVSAERTFLHLLEGGCQVPIGGYAYLDGDEVVLTALVGDPDGTTILKETVRGTEPTEVGKEAAELLISQGAKEIVDRVKEEMDQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: TSAD_META1
Sequence: MIIFAIESSHDDTSFALLDDNKPIWMKTITQTEIHKQYGGTVPEIASRLHVKNIGILIEDIKSQININKIDLIAYTKEPGLVGSLHVGYVVAQSLALILNKKIVGLNHLEGHFYSAFIGKEVIYPALGLLVSGGHSQLVLYNSKDDFKIIGQTQDDAVGEVYDKVARKLNLGFPGGPLIDQIWKNNHKLYTAHLTIPKTEGFFDFSFSGIKTNVINLINNCASRNEQINVNQIATEFQNTIVEYLKEHMETAIKKFSPKCIVLAGGVSANFAIREMFYSLHKNVFLPDLEYTTDNAMMIARLAYEKFRYNN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GERAB_BACSU
Sequence: MSQKQTPLKLNTFQGISIVANTMLGAGLLTLPRALTTKANTPDGWITLILEGFIFIFFIYLNTLIQKKHQYPSLFEYLKEGLGKWIGSIIGLLICGYFLGVASFETRAMAEMVKFFLLERTPIQVIILTFICCGIYLMVGGLSDVSRLFPFYLTVTIIILLIVFGISFKIFDINNLRPVLGEGLGPIANSLTVVSISFLGMEVMLFLPEHMKKKKYTFRYASLGFLIPIILYILTYIIVVGALTAPEVKTLIWPTISLFQSFELKGIFIERFESFLLVVWIIQFFTTFVIYGYFAANGLKKTFGLSTKTSMVIIGITVFYFSLWPDDANQVMMYSDYLGYIFVSLFLLPFILFFIVALKRRITTK
What is the function of this protein?
Involved in the germinative response to L-alanine.  Could be an amino acid transporter.  Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine.  Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence.
What are the official names of this protein?
Spore germination protein A2.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDD_BACCN
Sequence: MKQIFIGIIRFYQKFISPMTPPTCRFYPTCSHYGLEAFQTHGALKGFWLTLKRILKCHPFHPGGFDPVPDKKDDK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS15_STAMF
Sequence: MNKKRDKGQSHSTRPARAGPPRWLKLDMSPSDIELLVVELAKKGYTPSMIGIILRDQYGVPLVKQVTGKKLVQILEKHGIKLPVPEDLLFLMRKAVNLRRHLEEHPKDFHAKKGLLDLESKIHRLVKYYKRIGRLPPDWKYTPEQAKLIVSAYL
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RL32_ANADE
Sequence: MGVPKKRTSSMRRDRRRAANFKLKPVNVVKCPKCKEPVLPHRACPSCGTYKGEQITEAS
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: TRM1_HHV8P
Sequence: MAKELAAVYADVSALAMDLCLLSYADPATLDTKSLALTTGKFQSLHGTLLPLLRRQNAHECSGLSLELEHLLENVADALTTLGVCTSRKLSPEEHFSLLHLDITCNKHRSVRFNFYGNWALELKLSLINDVEIFFKRLSSVFYCIGSGSALEGLGEVLRFVGKLRGISPVPGPDLYVSNLPCLECLQEVCLTPNQGTSLQAMLPDTACSHICTPACGEPVRGLFENELKQLGLQTPESIPTTPCQSRVRQDDEIRQSSLMAVGDHHIFGEVTRSVLEISNLIYWSSGHSDATCDGDRDCSHLASLFTHEADMHKRRVDLAGCLGERGTPKHFFDCFRPDSLETLFCGGLFSSVEDTIESLQKDCSSAFYQQVNYTTALQKQNEFYVRLSKLLAAGQLNLGKCSTESCPSEARRQLVGGDKPEEVLRDAKHRQELYLQKVARDGFKKLSDCIRHQGHILSQTLGLRLWGSVIYNEASALQNHFLHRAQFISLPWQDLTVDCPTRFENSKYIKNSLYCQRLGREHVEILTLEFYKLITGPLSKRHTLFPSPPNVTLAQCFEAAGMLPHQKMMVSEMIWPSIEPKDWIEPNFNQFYSFENQDINHLQKRAWEYIRELVLSVSLYNRTWERELKILLTPQGSPGFKEPKPAGLTTGLYLTFETSAPLVLVDKKYGWIFKDLYALLYHHLQLSNHNDSQV
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: FUT7_ARATH
Sequence: MKTKLMITIFSCLLLWSMLLLLSFSNIFKHQLLGATINVGSKDSVKPRDRLLGGLLTADFDEDSCLSRYQSSLYRKPSPYRTSEYLISKLRNYEMLHKRCGPGTDAYKRATEKLGHDHENVGDSSDGECKYIVWVAVYGLGNRILTLASVFLYALLTERIILVDQRKDISDLFCEPFPGTSWLLPLDFPLMGQIDSFNREYSHCYGTMLKNHTINSTTIPSHLYLHLLHDYRDQDKMFFCQKDQSLVDKVPWLVVKSNLYFIPSLWLNPSFQTELIKLFPQKDTVFYHLARYLFHPTNQVWGMVTRSYNAYLSRADEILGIQVRVFSRQTKYFQHVMDQIVACTQREKLLPEFAAQEEAQVTNTSNPSKLKAVLVTSLNPEYSNNLKKMYWEHPTTTGDIVEVYQPSRERFQQTDKKLHDQKALAEMYLLSLTDKLVTSALSTFGYVAQGLGGLKPWILYTPKKFKSPNPPCGRVISMEPCFLTPPVHGCEAKKGINTAKIVPFVRHCEDLRHYGLKLVDDTKNEL
What is the function of this protein?
May be involved in cell wall biosynthesis.  May act as a fucosyltransferase.
What are the official names of this protein?
Probable fucosyltransferase 7, AtFUT7.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 37 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: NEDD1_HUMAN
Sequence: MQENLRFASSGDDIKIWDASSMTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNPVTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAESGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSEKIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF
What is the function of this protein?
Required for mitosis progression.  Promotes the nucleation of microtubules from the spindle.
What are the official names of this protein?
Protein NEDD1, Neural precursor cell expressed developmentally down-regulated protein 1, NEDD-1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: RIB4_SCHPO
Sequence: MFSGIKGPNPSDLKGPELRILIVHARWNLQAIEPLVKGAVETMIEKHDVKLENIDIESVPGSWELPQGIRASIARNTYDAVIGIGVLIKGSTMHFEYISEAVVHGLMRVGLDSGVPVILGLLTVLNEEQALYRAGLNGGHNHGNDWGSAAVEMGLKALY
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.  Also binds riboflavin with an unexpected high affinity.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase, Riboflavin synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: Y427_MYCGI
Sequence: MAATDLLAGRATLSRSLRLLSAFRFEQTDPDRFYGALASDTVAMVDDLWRATTGTSTRNLTVLDVGGGPGYFASAFTDAGLHYVGVEPDPGEMHAAAPRTHSRAGSFVRASGTALPFADGSVDICLSSNVAEHVAQPWRLGEEMLRVTRPGGLAVLSYTVWLGPFGGHEMGLSHYLGGYRAAERYTRRHGHRPKNDYGSSLFAVSAADGLRWARSTGALAAAFPRYHPRWAWGLTRVPGVREFLVSNLVLVLRPT
What are the official names of this protein?
Uncharacterized methyltransferase Mflv_0427.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: CCHL_CHICK
Sequence: MGLSASSPAATAQSAAEPSKQHQVASPPSECPMHQEKMRGCPMHMKASDRRAENTDDVPAHQERAYEYVACPVKSGASQVNDDIDPSNMMPPPNQLPSPDQPFPLSTVREESSIPRAHSDKKWVYPSEQMFWNAMLRKGWRWKDDDITSEDMTNIIKIHNQNNEQAWKEILKWEALHAMECPCGPSLMRFGGKAKEYSPRARIRSWMGYELPFDRHDWIVDRCGKEVRYVIDYYDGGAVDKNYQFTILDVRPAFDSLSAVWDRMKVAWWRWTS
What is the function of this protein?
Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
What are the official names of this protein?
Holocytochrome c-type synthase, Cytochrome c-type heme lyase, CCHL.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-type heme lyase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: RL3_SYNY3
Sequence: MSIGILGTKLGMTQIFDQESGISIPVTVVQAGPCPVTQVKTQDTDGYNAIQVGFLPVKEKALSKPELGHLKKSNTDPMRHLKEYRLTDAPNLQPGDAVTADIFQAGDLVDVAGQSMGRGFAGYQKRHNFRRGNMTHGSKNHRLPGSTGAGTTPGRVYPGKRMAGQYGASQVTVRRLTVVRVDAERNLLIIKGALPGKPGTLLNITPAKTVGRG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y2080_DECAR
Sequence: MLRYAIVFFIIALIAALFGFTGIAAGAVEIAKIMFFIFVLLALVSLVMGFTRRK
What are the official names of this protein?
UPF0391 membrane protein Daro_2080.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PP2A2_YEAST
Sequence: MDMEIDDPMHGSDEDQLSPTLDEDMNSDDGKNNTKARSNDEDTDEELEDFNFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSHQQNVVTIFSAPNYCYRCGNQAAIMEVDENHNRQFLQYDPSVRPGEPTVTRKTPDYFL
What is the function of this protein?
Exact function not known, phosphatase 2A performs an essential cellular function.
What are the official names of this protein?
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
Protein: RTNLT_ARATH
Sequence: MGEMGKAMGLLISGTLVYYHCAYRNATLLSLFSDVFIVLLCSLAILGLLFRQLNVSVPVDPLEWQISQDTASNIVARLANTVGAAEGVLRVAATGHDKRLFVKVVICLYFLSALGRLISGVTVAYAGLCLFCLSMLCQTSQSLGNCVLKRGNGQILEQEAHSDT
What are the official names of this protein?
Reticulon-like protein B22, AtRTNLB22.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SDA1_DROME
Sequence: MVRPNNNQLPENLPQLQNLIKRDPESYSDEFHIQYQHFLSLLEVFALNPSEENKSLDDIVMFVAQVAQCYPAVCEEFPKRLSDLLKNYATVLDPAMRNCFVKALILLRNKNLVPALDILELFFQLLRCPDKNLRTFLQTHIVTDIKNMNAKHKDMKLNSSLQAFMYSMLKDANPKAAKMSADIMIELYKKNIWNDSKTVNVIATVGCFSKVTKVLVTSLKFFLGHDEEDEEEDTDSENEVDLKGALMANRVNKKTKKRTKQLAQIKKQAVKAQKKKKNAPAFNFSGIHLVHNPQGMAEGLFKQLQATNERFEVKLMHLDVISRLIGIHDLFLFGFYPYITRFLQPHQRQVTRVLQFAAQASHELVPGDIIEPILKTIANNFITERNSSDVMAIGLNATREICMRCPLAMGEDLLQDLAMYKTYKEKSVMMAARSLITLYREQLPALLHKKDRGRQTEAQAERKVRAYGEREVHDTVLGAEALLKDSKTIDIESEDDTDSNDGEWVNVAHSDGEGGGADDDEEDEDEDEDDDDEDEDEENSNDEENEDEDNSDEGVESGEESAKAKKEKKDMRILNQKEAAQELALTRIFTDEDFKRINAANLKKTVTSARKRPLEQDRAEFVKLNSIEMIYKKRKHDKESRLETVQAGRQDRERFGWKDGRVNEHCSKTNREKRKTKNFGMLRHKARSKVKKSFKDKQQALRKHLLHQKKMK
What is the function of this protein?
Required for 60S pre-ribosomal subunits export to the cytoplasm.
What are the official names of this protein?
Protein SDA1 homolog, Mystery protein 45A.
What is the protein family that this protein belongs to?
Belongs to the SDA1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL14_PSYWF
Sequence: MIQTETILEVADNSGARRVQCIKVLGGSHRRYASVGDIIKVSVKEAIPRGRVKKGDVMNAVVVRTKKGVRRPDGSVLRFDDNAAVLLNQNKAPIATRIFGPVTRELRGDQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TLD_AGGAC
Sequence: MKILVTGGSGFIGKNLIYLLREKREFEVFGATVEETMDLTNPCSVQSVLEKTKPDFIVHLAALTFVPNNNPITFYLVNTIGTENLLRSIVDLNVAKLGVLCFSTAGIYGIQETKLLSESLTPKPVNHYSMSKHCMEHIVNKYRCFRGITVVRPFNVLGLGQNINFLVPKMVSAFVKKDKTIELGNLDSVRDFISVNDCCDIIYRLISKLIENETINICTGIGYSVYQIFQLLCEISMHQMEIKQNELFVRHDDIPQMIGDPSKLLNVLGNDYRFTSVRAILEEMYKNRLLELSI
What is the function of this protein?
Catalyzes the conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-6-deoxy-D-talose.
What are the official names of this protein?
GDP-6-deoxy-D-talose 4-dehydrogenase, GDP-4-keto-6-deoxy-D-mannose reductase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: ACP_ACICJ
Sequence: MSEVAEKVKKIVVEHLGVDEAKVTPEASFIDDLGADSLDTVELVMAFEEAFGVEIPEDAAEKIGTVKDAIDYIEKKKAE
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GVPA_MICBC
Sequence: MAVEKTNSSSSLAEVIDRILDKGIVIDAWARVSLVGIELLAIEARVVIASVETYLKYAEAVGLTQXAXXAX
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  GvpA type proteins form the essential core of the structure.
What are the official names of this protein?
Gas vesicle structural protein, GVP.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: HEM2_METSC
Sequence: MKFPYTRMRRLRKNSKIRSLVKETTLSKDDLIYPVFVKEGIKTKEKIPKMPGQYRYSVDELIDEAKKLEEKGLKAILVFGIPKKKDKYGSSAYDPNGIVQKSVKLLKEETDLVVITDVCLCQYTEHGHCGIVKNKKIVNDETLKYLSKVALSHAEAGADVVAPSDMMDGRVKAIREELEKNGFDDVIIMSYSAKYASSFYEPFRSAVYSSPAFGDRSTYQMDPPNSLEALREVKLDIDEGADIVMVKPALPYLDIIRLVKDTFGVPTAAYNVSGEYSMIKAAIDANYLSNKVIIETLLSIKRAGADLIITHFAPEIVEEI
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: CCD25_HUMAN
Sequence: MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFPDLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQDGNDSDEFM
What is the function of this protein?
Transmembrane receptor that senses neutrophil extracellular traps (NETs) and triggers the ILK-PARVB pathway to enhance cell motility (PubMed:32528174).  NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (PubMed:32528174).  Formation of NETs is also associated with cancer metastasis, NET-DNA acting as a chemotactic factor to attract cancer cells (PubMed:32528174).  Specifically binds NETs on its extracellular region, in particular the 8-OHdG-enriched DNA present in NETs, and recruits ILK, initiating the ILK-PARVB cascade to induce cytoskeleton rearrangement and directional migration of cells (PubMed:32528174).  In the context of cancer, promotes cancer metastasis by sensing NETs and promoting migration of tumor cells (PubMed:32528174).
What are the official names of this protein?
Coiled-coil domain-containing protein 25.
What is the protein family that this protein belongs to?
Belongs to the CCDC25 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endomembrane system. Note=Localizes to cytoplasmic membrane in tumor cells.
Protein: DCP1B_MOUSE
Sequence: MAAAAAGGLPGKGHDISLAALRRHDPYISRIVDVASQVALYTFGHRANEWEKTGVEGTLFVYTRSASPKHGFTIMNRLSMENRTEPITKDLDFQLQNPFLLYRNGTLSIYGIWFYDKEECQRIAKLMKNLTQSEQLKACHGAGSSPVTLSSGEGQEVDILQMLTKAKDEYTKCKTCSEPKQMTNSSAICDNPKLIKPVPVRPSSSQRLQGPAPSKTSDPEPQHLSLTALFGKQDKAPCQETVKPSRTFAHHHHHHHQQQQETRPVHHGVACSLSCEEPRKLSLPVEKQLCPAIQKLMLGSPGLHPLPQHPEQWSCKSGSPSPAGGILPGPVQLGSPWNGRVAHCTQSTCRGHKLLEQLQGAPGAVHKYNPCAPTGPAVATQVAPGQSVAQSQLVYFSGPLQPPAPGHQALRKEQGALPAQAVSLSGSQESSPTVLPTQELLRKLQVVHQEQQAAPRPALAARFPVSAQGSGTEKPLEAWVSKTASMEKQAPLLQSTCAPLRETDNGLMALGGQELPAASSNLLLPLQNWESSTVASRPLTRLQLQEALLNLIQNDDNFLSIIYEAYLFSVTQAAMRTT
What is the function of this protein?
May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay.  May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (By similarity).
What are the official names of this protein?
mRNA-decapping enzyme 1B.
What is the protein family that this protein belongs to?
Belongs to the DCP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPOA_SALRD
Sequence: MSNHGLQMPEGVHVEEVSDSEGQFVMGPLERGYGVTIGNALRRVLLSSLRGLAITAVKIDGVQHEFSTIPGVTEDVADLILNLKEVRFKADEMQEGHLHLNLEGPGNWTAADIDEATAEYDVLNPDQHVATLAEDAVVNVDLRVGYGRGYVPSEENKREDDPIGVIAIDSIFTPIKNVNYEVKPTRVGQKIDYEELLLDVETDGSLTPEEAITQGASILRDHVSFFIQLEEEPEPVVEEQEVDEEVKRIRELLAQPVDELDLSVRSHNCLKAANIKTIGDLVRREEDEMLKFRNFGRKSLQELVEVLDERGLQFGMDVEEYLEEKKAS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.