PharMolix/UniProtQA huggingface dataset:
Protein: PUR9_ECOK1
Sequence: MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDTIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEIDANEGSLTLETRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTKRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: KISHA_CHICK
Sequence: MSAIFNFQSLLTVILLLICTCAYIRSLAPSLLDKNKTGLLGIFWKCARIGERKSPYVAVCCVVMAFSILFVQ
What is the function of this protein?
Involved in the early part of the secretory pathway.
What are the official names of this protein?
Protein kish-A, Transmembrane protein 167, Transmembrane protein 167A.
What is the protein family that this protein belongs to?
Belongs to the KISH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein.
Protein: QCR7_SCHPO
Sequence: MKPVSLAKYIQKSPFLTKLLLPISNAYVHLSGYRKYGLRYDDLMLEENDDTQKALSRLPKMESYDRVYRIRRAMQLSIENKILPKSEWTKPEEDYHYLRPVLAEVIAERKEREAFDALIVKKPETQAHATSSPAHAH
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 7, Complex III subunit 7, Ubiquinol-cytochrome c reductase complex 14 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCRB/QCR7 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: KPYK_MYCIT
Sequence: MSRRGKIVCTLGPATNSDELILALVEAGMDVARLNFSHGDYADHKAAYERVRVASDATGRAVGVLADLQGPKIRLGRFATGPTYWADGETVRITVADCEGSHDRVSTTYKKLAEDAAVGDRVLVDDGKVCLVVDGIEGDDVICTVVEGGPVSNNKGISLPGMNVSAPALSEKDIEDLTFALDLGVDLVALSFVRSPADVELVHEVMDRVGRRVPVIAKLEKPEAVDNLETIVLAFDAIMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYPMAAVRTMSRIICAVEDNSTAAPPLTHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVKRLARLHTPLPLLAFTAWPEVRSQLAMTWGTETFIVPMMTSTGGMIRQVDKSLLELGRYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: MTNK_BACAC
Sequence: MGYYSLTEVTAVQYAKEHGYFEKKANVVCHEIGDGNLNYVFKLDDGEKSIIIKQALPYAKVVGESWPLSIKRATIESKALQIFAKYVPEYVPVVYSHDEELAVTVIEDLSRLTITRKGLIDGEEYPLLSQHIGRFLANVLFYTSDFGLQSEEKRVLEGTFVNPDLCKITEDLVFTDPFGHYDTNDYEPELQLTIDELWSDKTLKLKVAQYKYKFLTRKEALIHGDLHTGSIFSSPSETKVIDPEFATYGPFGFDIGQFIANLLLNALSREEEQRGVLFFHIEKTWSYFVETFTKLWIGEGVEAYTKEKQWLPIILQNIFTDAVGFAGCELIRRTIGLAHVADLDEITNKETRIQAKKQALSLGKELIKYESKNADIQLFRTLFQQTVSGGIKA
What is the function of this protein?
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
What are the official names of this protein?
Methylthioribose kinase, MTR kinase.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: YIDC2_BACAN
Sequence: MKKKLGLLAMVVALMAITAGCSEVNQPITPKSTGIWNEYFVYPLSQLITYFANLFGSNYGLAIVVTTLIIRFALLPLMIKQTKSTKAMQALQPEMVKLKEKYSSKDQATQQKLQQEMMQLYQKNGVNPLAGCLPIFVQMPILFAFYHAIMRTSEISKHTFLWFDLGQADPYYILPVVAAITTFIQQKLAMAGTAGQNPQMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFGIAQMYLIKGPEIKASKAGGSSK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 2, Foldase YidC 2, Membrane integrase YidC 2, Membrane protein YidC 2.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TM216_DANRE
Sequence: MADVCLRLQYACPWQSNMAAHGRQPVLSSTPLQILFHLNGWYFAAFFVAEILMFIYKGVILPYPQDNLILDVVLLLLFSGLETLRLFYGWKGNLCQRSLALFVSVAILVPCAVLSVYYLLLQTFVLRLEFVLNAVLLCFYGFELVLGVMTISIFSRANIY
What is the function of this protein?
Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition.
What are the official names of this protein?
Transmembrane protein 216.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: TX801_LYCSI
Sequence: MKLIIFTGLVLFAIVSLIEAQAENEKACLPQYQVCTDAPGNCCSDLVCDCYGRYKCGARIGRNCFCLQKGVIYKREN
What are the official names of this protein?
U8-lycotoxin-Ls1a, Toxin-like structure LSTX-H1, Toxin-like structure LSTX-H2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ESSB_STAAW
Sequence: MVKNHNPKNEMQDMLTPLDAEEAAKTKLRLDMREIPKSSIKPEHFHLMYLLEQHSPYFIDAELTELRDSFQIHYDINDNHTPFDNIKSFTKNEKLRYLLNIKNLEEVNRTRYTFVLAPDELFFTRDGLPIAKTRGLQNVVDPLPVSEAEFLTRYKALVICAFNEKQSFDALVEGNLELHKGTPFETKVIEAATLDLLTAFLDEQYQKQEQDYSQNYAYVRKVGHTVFKWVAIGMTTLSVLLIAFLAFLYFSVMKHNERIEKGYQAFVKDDYTQVLNTYDDLDGKKLDKEALYIYAKSYIQTNKQGLEKDKKENLLNNVTPNSNKDYLLYWMELGQGHLDEAINIATYLDDNDITKLALINKLNEIKNNGDLSNDKRSEETKKYNDKLQDILDKEKQVKDEKAKSEEEKAKAKDEKLKQQEENEKKQKEQAQKDKEKRQEAERKK
What is the function of this protein?
Component of the type VII secretion system (Ess).  Required for the secretion of EsxA and EsxB.
What are the official names of this protein?
Type VII secretion system protein EssB.
What is the protein family that this protein belongs to?
Belongs to the EssB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DNAA_MYCMS
Sequence: MNVNDILKELKLNLMANKNIDESVYNDYIKTINIHKKGFSDYIVVVKSQFGLLAIKQFRQTIKNEIKNILKEPVNISFTYEQEYKKQLEKDELIKKDHSDIITKKVKKINENTFENFVIGASNEQAFIAVQTVSKNPGISYNPLFIYGESGMGKTHLLKAAKNYIESNFSDLKVSYMSGDEFARKAVDILQKTHKEIEQFKNKICQNDVLIIDDVQFLSYKEKTNEIFFTIFNNFIENDKQLFFSSDKSPELLNGFDNRLITRFNMGLSIAIQKLDNKTATAIIKKEIKNQNIKSEVTSEAINFISNYYSDDVRKIKGSVSRLNFWSQQNPEEKIITIEIVSDLFRDIPTSKLGILNVKKIKEVVSEKYGISVNAIDGKARSKSIVTARHIAMFLTKEILNHTLAQIGEEFGGRDHTTVINAERKIETMLKKDKQLKKTVDILKNKILTK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAKLI_ARATH
Sequence: MKRRRLFFSVLLSILTLFINGPLITTAQSPPSSSTSCNRICGGIEIPFPFGIGRRDCFLNDWYEVVCNSTTSGKSLAPFLYKINRELVSITLRSSIDSSYGVVHIKSPVTSSGCSQRPVKPLPLNLTGKGSPFFITDSNRLVSVGCDNRALITDIESQITGCESSCDGDKSRLDKICGGYTCCQAKIPADRPQVIGVDLESSGGNTTQGGNCKVAFLTNETYSPANVTEPEQFYTNGFTVIELGWYFDTSDSRLTNPVGCVNLTETGIYTSAPSCVCEYGNFSGFGYSNCYCNQIGYRGNPYLPGGCIDIDECEEGKGLSSCGELTCVNVPGSWRCELNGVGKIKPLFPGLVLGFPLLFLVLGIWGLIKFVKKRRKIIRKRMFFKRNGGLLLKQQLTTRGGNVQSSKIFSSKELEKATDNFNMNRVLGQGGQGTVYKGMLVDGRIVAVKRSKVLDEDKVEEFINEVGVLSQINHRNIVKLMGCCLETEVPILVYEHIPNGDLFKRLHHDSDDYTMTWDVRLRISVEIAGALAYLHSAASTPVYHRDVKTTNILLDEKYRAKVSDFGTSRSINVDQTHLTTLVAGTFGYLDPEYFQTSQFTDKSDVYSFGVVLVELITGEKPFSVMRPEENRGLVSHFNEAMKQNRVLDIVDSRIKEGCTLEQVLAVAKLARRCLSLKGKKRPNMREVSVELERIRSSPEDLELHIEEEDEEECAMEINMDDSWSVDMTAPASLFDLSPKLDVEPLVPQRTW
What is the function of this protein?
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.  Required during plant's response to pathogen infection.
What are the official names of this protein?
Wall-associated receptor kinase-like 22.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: AMYR_DROSI
Sequence: MFKFALTLTLCLAGSLSLAQHNPHWWGNRNTIVHLFEWKWSDIAQECESFLGPRGFAGVQVSPVNENIISAGRPWWERYQPISYKLTTRSGNEEEFGDMVRRCNDVGVRIYVDVLLNHMSGDFDGVAVGTAGTEAEPRKKSFPGVPYTAQDFHPTCEITDWNDRFQVQQCELVGLKDLDQSSDWVRSKLIEFLDHLIELGVAGFRVDAAKHMASEDLEYIYSSLSNLNIDHGFPHNSRPFIFQEVIDHGHETVSRDEYKELGAVTEFRFSEEIGNAFRGNNALKWLQSWGTGWGFLPSGQALTFVDNHDNQRDAGAVLNYKSPKQYKMATAFHLAYPYGISRVMSSFAFDDHDTPPPQDAQERIISPEFDEDGACVNGWICEHRWRQIYAMVGFKNAVRDTEITGWWDNGDNQISFCRGNKGFLAINNNQYDLSQDLNTCLPTGTYCDVISGSLIDGSCTGKSVTVNENGYGYIHIGSDDFDGVLALHVDAKV
What are the official names of this protein?
Alpha-amylase-related protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSA_METMJ
Sequence: MKSSELFNRAKTLMPGGVSSPVRAIKPYPFYVERAAGSHLTTVDGADLIDCCLGYGPLILGHAHPEVREAIERQLEKGWLYGTPTPLELDLAGIITGDHPAVEMVRFVSSGSEATMAAIRLARGYTGKQDIIKIEGGFHGAHDAVLVKAGSGATTLGVPDSAGVLADLTAHTRQVPYNDTEALEALLAGNDDVAAFILEPVMGNVGPVLPDDGYLADVREITAAHDVLLILDEVITGYRAGIGGAEVLYDVKPDLATFGKIIGGGLPIGAFGGRCDIMELVAPAGPVYQAGTFSGNPASLAAGYATLRHLHDHPEIYRRLDDATRAIGEAAADAGKGTFVRIGSLFKHFFRDAAPRDYREVKECDTEAFSRFWKAMLEAGIFLPPSQFETNFLSAAHTTQDIKQIAEAYGSCLFA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP1_GORGO
Sequence: MARYRCCRSQSRSRCYRQRQTSRRRRRRSCQTQRRAMRCCRRRNRLRRRKH
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1, Cysteine-rich protamine.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YQGF_THEVB
Sequence: MISVLGLDLGRKRIGVAGCDRLGQLATGITTIYRRNFASDVAQLRRICQERGVEKLIVGLPYTLDGQLGSQARQVQHLAEKIGAALNLPVEYIDERLTSFQAEEILKQRRRSPRHHKDLVDQIAAALILQQWLDARSQTAKATLAAGDPQL
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_HELP2
Sequence: MSQLKLEEISSVIEEKIKNFELDCDMAEVGKVVSYADGVAKVYGLNGVMSYEVLEFETGDKGVAANLEEDSVGVIVFGFGNNIKEGTSVKRTKSLMKVPVGDAVVGRVLNALGEPIDGKGEIETNEFSLIEQKAPGIMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDKQTGKTTVAIDAIINQKGQNVICIYVAIGQKESTVAQVVRKLEEYGAMEYSVVINASASDSAAMQYLAPYSGVAMGEYFRDHARHALIIYDDLSKHAVAYREISLILRRPPGREAFPGDVFYIHSRLLERAAKLCDEKGAGSLTALPIVETQAGDVSAYIPTNIISITDGQIFLETDLFYSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFASDLDEASKKQLERGQRMVEVLKQAPYSPLPIEKQVVIIYAGAKGFLDSVSVKKVVDFEEQLHPFLEAKYPQVLEEIHTKKALDKDLEAMLRKVLEEFKLTYSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL7_ALIB4
Sequence: MAVSKEDVLEFISGLSVLELSELVKEFEEKFGVSAQPVAVAGGAVAAVEAVEEKTEFDVIIVDSGDKKINVIKEIRAITGLGLKEAKDAAEQTPSTIKEGISKADAEAFKAQLEAAGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: VPS35_HUMAN
Sequence: MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLRRESPESEGPIYEGLIL
What is the function of this protein?
(Microbial infection) The heterotrimeric retromer cargo-selective complex (CSC) mediates the exit of human papillomavirus from the early endosome and the delivery to the Golgi apparatus.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 35, hVPS35, Maternal-embryonic 3, Vesicle protein sorting 35.
What is the protein family that this protein belongs to?
Belongs to the VPS35 family.
Protein: LON_MYCAP
Sequence: MLFDREVAKLEITDELITQTTYWKQIIDEYTKDNSNGAEIINKARIMLVYYRPAEDNRVILESELQSKPTATYADVLENVNISNLDSNMTLCQVESVEKVYDNGSQKWHYIATLKAIHKYILQDIYGDEETISSSSIDIEKLPLKYIEGMVATRFGSENNGDEMALADPSLDFNGFEEVINTLIYDRNWNDAMLLYRYIRGYSAKEIRNWTKGTSEMMPDFINDDESRLETLVRALTGFFLLPPYELFTIYSMPSALHQFEALKSNFVLMVRLIKKFINELNLGNTDKLLNIYNALTDNELFKNSMEQIKENSELEVQFNYEVERIYKWHKEYLQLGYITEDDLKLIISLIEQNQNNLSKRSSKKDTSAMKDKIDKELNKKIQSNLDKQQKEFLLREKMKAIKEQLNEADDEDGDDEYSKIVNDPVLKQMYPEWIIKAIKTERDKLKNMMSSSPDANITQTYISNLKKLPWRKVEVENLDINRAREILDKNHYGLKEVKERVIEYLSLIINHRNINKESSEKDLIKIDDHNQIDLQLFKENTKNKAQKQFNNVPILTLVGPPGTGKTSLARSIAEALDKSYVKLSLGGLHDESEIRGHRKTYVGAMPGKIIKGLQSAGVSNPLILLDEIDKMSSDIKGDPTSAMLEVLDPEQNTKFQDNYIEHEYDLSKVLFIATANYYENIPAPLLDRVEIIELNSYTINEKIKIAKEHLVEVVLAQAGLKPDQFIIDDKALEFIIKHYTAEAGVRSLKRNLDKIARKIVTKIVSGEKIDKFVIDQNNIPELLGTPKISESEKEMQPQIGSVNGLAFTSIGGTTLQIEVSWFKSKQPGIRLTGQLKEVMQESAKIALSYVRANAEKFGIKNVDFDTTEIHVHVPEGAVPKDGPSAGVTFTTALISALAKIPVSQEVAMTGEITLRGKVLEIGGLKEKSFAAFKKGIKTVFIPKNNEKNLSDIPEEVKEAINFIPVSHYEQIWEHLFKGKKSDESETESKKKKQSK
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner (By similarity).
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN3_DANRE
Sequence: MASALEQFVNNVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDIQEHSLGVLAVLFVKFSMPNIPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGISILKQAIDKMQMNTNQLTSVHADLCQLCLLAKCFKPAVPFLELDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFFEQAITTPAMAVSHIMLEAYKKYILVSLILHGKVQQLPKYTSQIVGRFIKPLSNAYHELAQIYATNNPAELRALVNKHSETFTRDNNTGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIYASINQKDGMVCFHDNPEKYNNPAMLHKIDQEMLKCIELDEKLKSMDQEITVNPQFVQKSMGTQEDDVGSKTSSYS
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity).  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 3, Signalosome subunit 3.
What is the protein family that this protein belongs to?
Belongs to the CSN3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: P5I13_MOUSE
Sequence: MVHPPPPPPRLLLVALVGLLSLREVVAEPAEEAGTPCPEGLWPVPPQVLPRVTYTQVSQGQAEGIAFFYHPCAHPWLKLQLALLAHLYVAKPTLIPDFSLTWDRPLVLTAWGTALELAWIEPAWVAHWLKRQRRRKQRKSVWFLSDNLFGPTPTMPASRRGKLCGRRCVQAPTLAFALRSWRPPGAQVTSRGSGRSSISVVKRRGLRAALGLQSTPPGLRVSLASSQSLKAQQLTLGTSSVAPVSLTTGGPGGNGRSRTEAQMPSGQGNHGGCACPGQVSPAPRAAGPPRVARGPTPRTEEAAWAAMALTFLLVLLTLATLCTRLHRNFRRSESIYWGPTADSQDTVAALLKRRLPLPSRRIKRSRRRPLLPPTPDSGPDSESSD
What is the function of this protein?
May act as a tumor suppressor.  Inhibits tumor cell growth, when overexpressed (By similarity).
What are the official names of this protein?
Tumor protein p53-inducible protein 13.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein; Extracellular side. Cytoplasm. Note=Associates with unknown subcellular structures in the cytoplasm.
Protein: UNG_HELPG
Sequence: MKLFDYAPLSLAWREFLQSEFKKPYFLEIEKRYLEALKSPKTIFPKSSNLFYALNLTPPSAVKIILLGQDPYHSTYLENEQELPVAMGLSFSVEKNAPIPPSLKNIFKELHANLGVPVPCCGDLSAWAKRGMLLLNAILSVEKNQAASHQYIGWEAFSDQILMRLFKTTAPLIVVLLGKVAQKKIALIPKNKHIIITAPHPSPLSRGFLGSGVFSSVQKAYREVYRKDFDFSL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_PSEPK
Sequence: MRRPMVAGNWKMHGTRASVAELTKGLSNLALPSGVEVAVFPPALFINQVIDGLAGKEITVGAQNSAVQPEQGALTGEVAPEQLVEAGCKLVLIGHSERRQIIGETDEVLNRKFAAAQAKGLKPVLCIGETLEEREAGKTLEVVGRQLSSIIEAFGVKAFADAVIAYEPVWAIGTGLTATPQQAQDVHAAIRGQLAAEDAEVAAKVQLLYGGSVKAANAAELFGMPDIDGGLIGGASLNADEFGAICRAAGN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_SALTI
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGEAVLAGSIIVRQRGTKFHAGTNVGCGRDHTLFAKADGKVKFEVKGPKNRKYISIVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: M870_ARATH
Sequence: MVSSSRIARSFTRYTSALQRHTIVTKIKQKFPCPRSRTQGQSRRSETHTISRRRSCRAIARSNLGRVSSVTLPWFSCPSPAVVALAKKPFRTARSSCPRSRKSSRCRKSLLSWTAHHLLDEFPKRRIWVFLSFRIGGSLHRRHAMEKNICSTRARIRLISAISLLSKPIVEIVVGYPQSEDRRL
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00870, ORF184.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YIDC_RICRS
Sequence: MNNNIINLIAAIILSLSIIFGWQYFVVKPEQKKQQQQIAVQKAENLKKQQLKALVEPATGIVVQEESQVQRIKIESESLTGSISLKGLRFDDLILKKYKQDLSKNSPEVRLFSPANTENAYFAEVGLVSNLSSVKLPNNDTIWNSDSEILSPEKPVHLFWVNEDGVKFLVTITVDENYLFTIEQTIVNNSDKELPVQSYGLINRKYIAVEKAVNILHQGPIGCIDENLKEYSYDDIKDKKSEKFAASKVDWIGITDKYWLSSLIPDKSSNYSSNFNYALKQGIERYQVDFISPVQIIKPGKNFSIKSRIFAGAKKVDLLDKYEKQYDIKLFDRAIDFGWFYIITKPVFYAMNFFYGYVGNFGVSILIVTVIIKLLMFTLANKSYRSMKKMKNLQPEIDRIKNLYSDDKARLNQEIMALYKKEKVNPVAGCLPILVQIPVFFSIYKVLYVTIEMRQAPFYGWIKDLSAPDPTTIFNLFGLLPFAPPSFLMIGAWPILMAITMFLQQKMSPEPADPMQAQVMKFMPLIFLFMFSSFPVGLLIYWSWNNILSIIQQYYINKFN
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GOB1_BRUMA
Sequence: MTETVTDQGKQRSSKLQKNEAAKDEQVEGKGKETLESGTDKSAEQNSSLLVGQPDVIDNDNVQTVDDFKNLMYKMQETRRAIVFALLNEKDLTKDDVEILKRAYEKLTDNQTHSFQREMCTLTTKLSVNIGDETRGLEKDLKYLDALMNIRREEPNLLWPIIMSRVDLFSILANYHPKGKETFLKEYEDTVKFLKTFISSEAITGKKPIFITDWDGTMKDYCSQYATNLQPVYSAVGMTRFAASFTRISAVLTAGPLRGPGILDLTAMPIDGPVMFSGSWGREWWLSGKRVVHQDGITDEGFNALQRLDDEMKDLLHTSDYAPFALVGSGVQRKVDRLTLGVQTVCHHVTSELSNRYQMAVKERMHRVDPNSQILVFDPSTELEVEVVAHNSGIIWNKGNGVERLIKSLGDSLQSPGKILICGDTLSDIPMVRQAVKQNPDGVLAIFVGAKMSLREEVKQVIGDESRCCFVSCPDVIHAAMSQILNEHCIGK
What is the function of this protein?
Catalyzes the hydrolysis of trehalose 6-phosphate to trehalose and phosphate; prevents the accumulation of toxic levels of trehalose 6-phosphate.
What are the official names of this protein?
Trehalose-phosphatase, Trehalose-6-phosphate phosphatase, TPP.
What is the protein family that this protein belongs to?
Belongs to the gob-1 trehalose phosphatase family.
Protein: FLGH_SHIB3
Sequence: MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSVNASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVSSTQVVDARIEYVGNGYINEAQNMGWLQRFFLNLSPM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.