PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_LEPIN
Sequence: MNKGKIKQIIGSVLDIEFENGELPEIYNALEIETNVSGKKETIIAEVQTHIGGKAVRAIALSSTDGLIRGQEVSNTGKPISVPVGDATLGRIFNVLGKTIDEGPAITVKETRPIHRAAPSFDELTSKTEVFETGIKVIDLLAPYIKGGKTGLFGGAGVGKTVLIQELINNIAKQHGGFSVFAGVGERTREGNDLWREMKESGVIDKTVLCYGQMNEPPGARLRVALSALTMAEHFRDSIGTDVLLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPANAFAHLDATTVLSRAISDKGIYPAVDPLDSTSRVMNAQVLGEEHYLVAREVQRILQRYKDLQDIIAILGMDELSEDDKVLVARARKIEKFLSQPFHVAEVFTGAPGKYVKLADTVRSFKEVISGNYDHLPEQAFYMVGSIDDAIEKAKGYKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ILVC_DEHM1
Sequence: MAVIYYDKDCDLSLIEKKIIGIVGYGAQGHAHAQNLRDSGLKVIVACVEGGRGWKKATADGFEVMCVAEMAKKADIIMMLAPDTSQAKIYKDSVEQGLTPGKMLMFAHGFNIHYGQIVPPSFVDVTMIAPKCPGYMLRQVFTEGAGAPSLIAVEQDASGKAKEIALAYAKGIGSNRAGVLETTFAEETETDLFGEQAVLCGGTTSLVKAGFETLVEAGYQPEVAYFECLHELKLIVDLMYQGGIAYMRDSISDTAKYGDFTRGPRVINEETYETMGEILGEIQDGSFAKEWILENQAGRPVYNSLRRMESEHLIEEVGAELRSMMSWLKKKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ALR_NITMU
Sequence: MSRPIQALIDPAALERNLAIVRRHAPRSRVMAVIKADAYGHGLLCAAEALAEAEGFALLELDAAVRLREAGYRQTILLLEGFFDIDELSWIEQYRLSTVVHHPEQLAMLEAVRRRATLDVFLKLNSGMNRLGFTPTEFPAALEHLKANPAVRQITLMTHFACADEPDRNDSIAAQLQCFNLAAGGRYMPRSLANSAAILRFPEAHADWVRPGIMLYGSSPLAHTTAEQLGLQPAMTVSSRIISVQTLRPNDGVGYGHAFRAGSSMRVGIVAGGYADGYPRHAPTGTPVLVKGRRTRIVGRISMDMLHVDLSEIEDAGVGSPVTLWGRGMPVDEVARAAGTLGYELLCAIAPRMQRVT
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: DHE4_PENCH
Sequence: MMQNLPFEPEFEQAYKELASTLENSTLFQKKPEYRKALQVVSVPERVIQFRVVWEDDKGQVQINRGYRVQFNSALGPYKGGLRFHPTVNLSILKFLGFEQIFKNALTGLNMGGGKGGSDFDPKGKTDNEIRRFCVSFMTELCKHIGADTDVPAGDIGVTGREVGFMFGQYKKIRNQWEGVLTGKGGSWGGSLIRPEATGYGVVYYVEHMIQHASGGKESFAGKRVAISGSGNVAQYAALKVIELGGSVISLSDSQGALVLNGEEGSFTAEEINTIAEIKVQRKQIAELATQDAFSSKFKYIPGARPWTNIAGRIDVALPSATQNEVSGDEAKALIAAGCKFIAEGSNMGSTQEAIDVFEAHRDANPGAAAIWYAPGKAANAGGVAVSGLEMAQNSARVNWSREEVDSRLKKIMEDCFNNGLSTAKEYVTPAEGVLPSLVAGSNIAGFTKVAEAMKEHGDWW
What are the official names of this protein?
NADP-specific glutamate dehydrogenase, NADP-GDH, NADP-dependent glutamate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: WHIA_CLOBH
Sequence: MSFSLKVKNEVCKHVEVNKQEAIAELSAIMKVSGTLLFTNKQFNFKITTENAAIARLVFKILKEHFGIHTEIMIKKNNSLKKNNIYIILISEEEGVKSLLKEVGIIKETINVFSLDYNIPKSIIECDECRRAYIRGAFLGGGSISNPEKTYHLEFVTHNEEYAKDLSNLINSYNLNSKVIKRKNSYIIYLKEGEQIVDLLNIIGAHASLLELENVRIMKEMRNNVNRLVNCETANLSKTVNAAVRQVESIKFIEREIGLGRLPKNLRDVAELRIKYPDESLRELGKMLNPPVGKSGVNHRLRRIEKIADELKQGI
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: COXX_MYCSJ
Sequence: MSIRERHLSHGAPSRIRTTVLAYLALTKPRVIELLLVTAIPAMLLADRGSVDPLLILNTLIGGMLAAAGANTLNCVADADIDKKMKRTARRPLARDTVPTRNALIFGLVLSVGSFFWLWGTSNLLSGLLAVATIAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFAIIFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTRQILIYTWLTVLTTLALALATGWLYASVAVLAGTWFLVMAHQLYNGVKRGEPVKPLRLFLQSNNYLAVVFAALAVDSVLALPTLLGS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEGT_GEOSE
Sequence: MNVPMLDLSEQYEQLKPEIMRVLDEVMRSSRFILGDYVKKLEADIAAYSRAKHGIGCGNGSDAIHIALQAAGVGPGDEVITTAFTFFATAGSIARAGAKPVFVDIDPVTFNIDPAQVEAAVTEKTKAIIPVHLYGQMADMEAIAAIAKRHGLVVIEDAAQAIGAKYNGKCVGELGTAATYSFFPTKNLGAYGDGGMIITNDDELAEKCRVIRVHGSKPKYYHHVLGYNSRLDEMQAAILSVKFPHLDRWTEQRRKHAATYTRLLEEAVGDLVVTPKEVDGRYHVFHQYTIRAPKRDELQAFLKEQGIATMVYYPLPLHLQPVFASLGYKEGQLPEAEKAAKEALSLPMFPELKEEQQQYVVEKIAEFYRHFA
What is the function of this protein?
This membrane protein may function as a sensor protein and may transfer the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of the genes.
What are the official names of this protein?
Pleiotropic regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GPMA_BARHE
Sequence: MERTLVLIRHGQSEWNLKNLFTGWKDPGLTEKGRTEAIAAGKKLKETGLKFDIAYTSALQRAQKTAQNILEQMEQSDLELIKTPALNERNYGDLSGLNKDEVRQKWGEQQVQIWRRSYTIAPPNGESLRDTGARVWPYYLHHIQPHILRSQTVLIAAHGNSLRALIMALEGLNSEEIISQELATGIPIVYTFNSDSTISSKTIITP
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ASZ1_DASNO
Sequence: MAAAVGLRGLAVAGGGESTDSEDDGWEIGYLDRASQKLTGLLPTEEKNETFKKALTTGDISLVEELLDSGISIDSSFRYGWTPLMYAASVANVELVRVLLDRGANASFDKDKQTILITACSARGSEEQILKCVELLLSRNADPNVACRRLMTPVMYAARAGHPQVVAVLVAYGAEVNTQDENGYTALTWAARQGHKNVILKLLELGADKMLQTKDGKTPSEIAKRNKHLEIFNFLSLSLNPLEGKLQQLTKEETICKLLTTVSDKEKDHIFSSYAAFEDLEIFLHGLGLEHMTDLLKERDITLRHLLTMRKDEFTKNGITSRDQQKILAALKELEVEEIKFGELPEVAKLEISGDEFLNFLLKLNKQCGHLITAVQNIITELPVNSHKIVLEWASPQNFTSVCEELVSNVEDLSEEVCKLKDLIQKLQNERENDPTHIPSMDEVSSWNNRILKRTAFTVCGFGFLLFICKLTFQRK
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: LYS_BPB30
Sequence: MATYQEYKSRSNGNAYDIDGSFGAQCWDGYADYCKYLGLPYANCTNTGYARDIWEQRHENGILNYFDEVEVMQAGDVAIFMVVDGVTPYSHVAIFDSDAGGGYGWFLGQNQGGANGAYNLVKIPYSATYPTAFRPKSFKNAVTVTDNTGLNKGDYFIDVSAYQQADLTTTCQQAGTTKTIIKVSESIAWLSDRHQQQANTSDPIGYYHFGRFGGDSALAQREADLFLSNLPSKKVSYLVIDYEDSASADKQANTNAVIAFMDKIASAGYKPIYYSYKPFTLNNIDYQKIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAGGLDKNIVLLADDSSKMDIPKVDKPQELTFYQKLATNTKLDNSNVPYYEATLSTDYYVESKPNASSADKEFIKAGTRVRVYEKVNGWSRINHPESAQWVEDNYLVNATDM
What is the function of this protein?
The endopeptidase activity cleaves the bacterial peptidoglycan between D-alanine and L-alanine (PubMed:15256551, PubMed:17021237).  The N-acetyl-muramidase activity cleaves between N-acetylmuramic acid and N-acetylglucosamine bonds (PubMed:17021237).
What are the official names of this protein?
D-alanyl-L-alanine endopeptidase, 1,4-N-acetylmuramidase, B30 lysin, Endoysin, Glycosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 25 family.
Protein: VATB_METM5
Sequence: MDAMQKTIEYTSVSRIAGPLMVIDGIEGIAYGEIVDITTPNGDKRTGQVLEAREEIAVVQVFEGTSELNTSETKVRFTGDTAKIGVSHDMLGRIFNGAGKPLDGGPEIIAEKKLDINGYPLNPVSRNPPNAFVQTGVSTIDGTNTLVRGQKIPIFSGSGLPHNKLATQIARQAKVRGEGEQFAVVFAAMGITGEESNYFMDEFKKTGALEKAVVFINLADDPAIERILTPRIALTTAEYLAYEKGMHVLVILTDLTNYCEALREIAAARNEVPGRRGYPGYMYTDLACLYERAGRVKGKEGTVTQIPILTMPDDDITHPIPDLTGYITEGQIVLSRELNRKGIYPPVDILPSLSRLAGNGQGEGKTRDDHSKVISQAYAAYAEGRGLRDLVAVVGEEALTERDRSFLKFADAFENSIVTQGVDEDRSIEETLDYIWGLLTILPREELKRVSDELIEKYLPKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CA1A_CONLI
Sequence: FRGRDAAAKASGLVGLTDRRGCCSHPACNVDHPEICG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin blocks alpha-3-beta-2/CHRNA3-CHRNB2 nAChR with high selectivity (IC(50)=8. 67 nM (on rat) and 17. 5 (on human)) (PubMed:24398291).  Has also weaker activity on alpha-6/alpha-3-beta-2-beta-3 (CHRNA6/CHRNA3-CHRNB2-CHRNB3) (IC(50)=108 nM (on rat)), alpha-6/alpha-3-beta-4 (CHRNA6/CHRNA3-CHRNB4) (IC(50)=121 nM (on rat)), alpha-3-beta-4 (CHRNA3-CHRNB4) (IC(50)=148 nM (on rat)), and alpha-7/CHRNA7 nAChRs (IC(50)=3000 nM (on rat)) (PubMed:24398291).  When tested on mouse with hot-plate tests, this toxin significantly increases the base pain threshold and shows analgesic effects (PubMed:26742048).
What are the official names of this protein?
Alpha-conotoxin LvIA, Alpha-CTx LvIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_CLOPS
Sequence: MEILKSMIDPKIVMAIVISFIVASILGPIIIPLLHKLKFGQNIRQEGPKSHLKKAGTPTIGGLIFIFATIITMFVMVGNPTDEAMIALYSFVGFGFVGFLDDLLKIIKKKNEGLTSGQKMILLLIISGFLTWYAYKYIGTSINIPFLNGQINLGLFYIPAAMFYFAGVTNAVNLTDGLDGLATSVTVLVTTFLGIISYNLGHISLAIFCVALAGALLAFLRFNAFPARVFMGDTGSLALGGAVAMVALILKMPLILVLIGIIYVIETLSVILQVASFKLTGKRIFKMAPIHHHFEQLGWSETKIVSVFSIITVVFCFIAFASL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL20_MYCBP
Sequence: MARVKRAVNAHKKRRSILKASRGYRGQRSRLYRKAKEQQLHSLNYAYRDRRARKGEFRKLWIARINAAARLNDITYNRLIQGLKAAGVEVDRKNLADIAISDPAAFTALVDVARAALPEDVNAPSGEAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ISCS_SHEPC
Sequence: MKLPIYLDYAATTPVDPRVAEKMFQYMTMDGIFGNPASRSHRYGWQAEEAVDIARNQVADLINADHREIVFTSGATESNNLAIKGVAHFYNKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLEPASNGIIPMERLEAAMRDDTILVSIMHVNNEIGVIHDIDAIGELCRSKGIIFHMDAAQSAGKLPIDVQATKVDLISISGHKMYGPKGIGALYVRRKPRIRLEAQMHGGGHERGMRSGTLPTHQIVGLGEAAAIAKAEMATDNERIGRLRDKLWNGIKHIEETYINGDLTQRFCGSLNVSFNYVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTEEEIDHAIETITQSIDKLREMSPLWEMFKDGIDLNQVQWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUE_ECOK1
Sequence: MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGYLAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGKNSETKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTLELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS
What is the function of this protein?
Exporter of leucine.
What are the official names of this protein?
Leucine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FADS6_BOVIN
Sequence: MEPAGGAPRESARAEALLGELEARVQEVVRASSWWERHGVDCAILALSLLALPPGFLCLRSDSPLVFALGITILGVCHYTLTVKGSHLATHGALTESRGWSKVWTLFFVEVCTSFTAEYAKYGHVKMHHGYTNVLGLGDSSTWRLPCLNRYVYMFLAPLLIPIITPLVAVERLREVELRTALRTLGLISLGLYSQYWLLLNVSGFQSPSSALACMLITRSLLAHPYLHVNIFQHIGLPMFSPDKKPRRIHMMSLGVLNLPRLPVLDWAFGHSLISCHVEHHLFPRLSDNMCLKVKPVVSQFLHEKQLPYNEDSYLARFWLFLQRYEEFMVQTPPITELVGLQ
What are the official names of this protein?
Fatty acid desaturase 6.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CRTC_RUBGE
Sequence: MRAAESGADARVRPVDRVEPADAPAGDAGGLRAAVPGDGGSAVRPGDARLDVLVPPGLVDEPAAGALPGGGQRAPGAGRADGGDVRPVGGRDADGAPRFDQPVPPGGYLWWYVDAVSDDGRHGLTFIAFVGSVFSPYYAWAGGPKADRADPENHCALNIALYGDAGKRWTMTERGRRWMRRSRDEFVIGPSRLHWDGESLLVEFDEVGVPIPRRVKGRVRVWPKALCRFVTSLDSGGRHRWGPIAPCSRIEVELDSPRVRWSGHAYLDSNEGDEPIDRPFREWDWSRATMADSSTAVIYDVRQKRDGDRVIAERFLLDGSTESFEAPPRQPLPTTLWRIGRTMRTEPGVPALVEQTLEDTPFYARSMVRSGLLGEVVTSVHETMLLPRVITLPVRLMLPWRMPRRA
What is the function of this protein?
Involved in the biosynthesis of carotenoids spheroidene and spirilloxanthin.  Catalyzes the hydration of neurosporene to the corresponding hydroxylated carotenoids 1-HO-neurosporene and 1,1'-(HO)2-neurosporene and that of lycopene to 1-HO-lycopene and 1,1'-(HO)2-lycopene.  Can also act on demethylspheroidene, spheroidene, 1-HO-3,4-didehydrolycopene and geranylgeraniol.
What are the official names of this protein?
Acyclic carotenoid 1,2-hydratase, 1-hydroxyneurosporene hydratase, Hydroxylycopene hydratase, Hydroxyneurosporene synthase, Lycopene hydratase, Neurosporene hydratase.
What is the protein family that this protein belongs to?
Belongs to the CrtC hydratase family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: EFP_PSESM
Sequence: MKTGKELKPGTVIRLENDPWLVQKAEFTKSGRNSAIMKTKLKNLLTGYKTEIVYSADDKLDDVILDRKEATLSFISGDTYTFMDTTDYTMYELNAEDIESVLPFVEEGMTDVCEAVFFDERLVSVELPTTIVRQVDYTEGSARGDTSGKVMKPAKLKNGTELSVADFIEIGDMIEIDTREGGSYKGRAK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDAR2_ARATH
Sequence: MAEEKSFKYVIVGGGVAAGYAAREFFNQGVKPGELAIISREQVPPYERPALSKGYIHLENKATLPNFYVAAGIGGERQFPQWYKEKGIELILGTEIVKADLAAKTLVSGTGQVFKYQTLLAATGSSVIRLSDFGVPGADAKNIFYLRELEDADYLAYAMETKEKGKAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGEVTEVKLKDGRTLEADIVIVGVGGRPIISLFKDQVEEEKGGLKTDGFFKTSLPDVYAIGDVATFPMKLYNEMRRVEHVDHARKSAEQAVKAIKAAEEGNSIPEYDYLPYFYSRAFDLSWQFYGDNVGESVLFGDNDPESPKPKFGSYWIKERKVVGAFLEGGSPEENNAIAKLARAQPSVESLEVLSKEGLSFATNI
What is the function of this protein?
Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process.
What are the official names of this protein?
Monodehydroascorbate reductase 2, AtMDAR2.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y116_BAUCH
Sequence: MFSKSGMSDLMKHAQRMQEQMQQMQGEIAKLEVNGESGAGLVKVTINGVYHCRRVEIDSSLLQDDKDMLEDLITAAFNDAVRRITEIKKDKMTSLSSSLQMPLGFNWNMPFL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BCI_0116.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MZRA_ERWAC
Sequence: MTTASIKKRDPRRRLLPWLIVAFVALIGLAMIPALFRHDSTLQIRASRQGVSLPDGFYVYQTLSAQGIHIQSITPEQDSLVIRFDSPEQSYAAERVLRKLFAQSFDIAHQPGPGAASWINRISLLPQFVG
What is the function of this protein?
Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
What are the official names of this protein?
Modulator protein MzrA.
What is the protein family that this protein belongs to?
Belongs to the MzrA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL17_BACC1
Sequence: MAYRKLGRTSAQRKAMLRDLATDLIINERIQTTETRAKELRSVVEKMITLGKRGDLHARRQAAAFIRNEVANAETGQDALQKLFADVAPRYAERQGGYTRIAKIGPRRGDAAPMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: OFOA1_AERPE
Sequence: MRKDVVLLVGGAQGSGLETTMQVLAPAYASLGYGVLANREYFSNIVGRHSYIHIRVSSSGEARPLYYPADFLGAMDAETVFTHWDDIGEGAFLLYDLGTARMRLQQIASMEPDLRSRLMQQYREAGIEPFTVEKVVEYLEREKRVRVIGLSFTALFDVLIKKHGLSRAQAQRFRSSILIGAIAGLTSLDREALDLGLQRRFGSRPKVLEINRDFIASVADEVEKEYGAQLKLEPAEPKSGEYVVASGNDVVAMGKVVGGVRYQAYYPITPASDESVLLEEFEGLKIDGESLGSIAILQTEDEIAAVSSVIGAALTGARASTATSGPGFSLMVEALGWAGKNDVPMVITYYQRGGPSTGLPTRGSQSDLLFSLFASHGEFPRIILSSGDHLEAFYDAIEAYNLAERFQMPVIHLLDKFLANMVASVPFPDWKAIKIDRGKTLFKAPTGPFKRFPRDQPLADRPVLGSGAITWYTGDENDEYGHIDEDPVNRLVMYERRWKKMEIADREIPEDFRVKYYGDEDAEVLLVGWGSVKIPALEAIERLREMGVNAAYLHLRMLSPLPKRRVSEVLSRFDADRVIAVEANYLGQASKIVTMETGFMFRKYILKWTGRPVYLHELVEGVLDIVRNGRDKVVLSYGK
What is the function of this protein?
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as pyruvate, 2-oxobutyrate and glyoxylate to form their CoA derivatives.
What are the official names of this protein?
2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha, OFOR1.
Protein: AROE_CHLPD
Sequence: MMQPEKILGLIGRNIAYSRSPLIHNTACDLLALPYVYTIFNIASADLIEPAIAGARALGIAGLNVTTPYKTTVVPFLDELSPEAASIGAVNTIVNNNGHLAGYNTDIAGFAAPLRPYAQRIKGNPVSVFGNGGAALAAIEAFRIFFHPCCVYLFVRDSAKASAMLENYVHRDIVTLCLIEELFSGESGAIAKIQRSLVIVNATPIGTAGRQNETETSILPLDTELLHPDHIVYDMVYNPLFTPLIKAAKASGAATISGIEMLLGQAARSFELWTGKEMPLEQVRAVLINNLLSSP
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MNHA2_STAA3
Sequence: MSLVYLLIAILVIMAMILLMSKRRALAKYAGYIALVAPVISSIYFLIQIPSVAKLQYLSTSIPWIKTLDINLDLRLDGLSLMFSLIISLIGIAVFFYATQYLSSRKDNLPRFYFYLTLFMFSMIGIVLSDNTILMYIFWELTSVSSFLLISYWYNNGDSQFGAIQSFMITVFGGLALLVGFIMLYIMTGTNNITEILGQADHIKNHGLFIPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLLRFTPLLGLSNMYVYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAMVGIGGGYAQHQQDAIASIYVFVLFGALFHLMNHAIFKCALFMGVGILDHEAGSRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLISMIAIVFVGVIASVFTFTYALYMVKEVFWTKYDSKVFTKKNIHEPWLFSLPSLILMVLVPVIFFVPNIFGKGIIVLALRAVSGGNHQIDQLAPHVSQWHGFNIPLLLTIIIILLGSVLAIKVDWKKVFTGKIRQISVSKSYEMVYRHFEKFATKRFKRVMQDRLNQYIIMTLGIFMIIIGYGYIRIGLPKVHQLHVSEFGALEIILAIVTVTIGISLIFIRQRLTMVILNGVIGFVVTLFFIAMKAPDLALTQLVVETITTILFIVSFSRLPNVPRSNANKKREIIKISVSLLMALIVVSLIFITQQTDGLSSISDFYLKADKLTGGKNIVNAILGDFRALDTLFEGLVLIITGLGIYTLLNYQDRRGQDERE
What are the official names of this protein?
Putative antiporter subunit mnhA2, Mrp complex subunit A2, Putative NADH-ubiquinone oxidoreductase subunit mnhA2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSBW_BACC2
Sequence: MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYKEDVGEITIVFGLYEDRLEIMAADNGVSFDFSSLKSKVGPYDINKPVEHLPENGLGLYLINTLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYNSY
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: DCDB_COREF
Sequence: MLLSDRDIRKSIDSGDLGIDPFDPLLIQPSSIDVRMDRYFRVFNNSKYTHIDPKLNQDELTSLVEVADGDPFVLHPGEFVLAATLEKFTLPHHLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKVGQLALFMMSSPAETPYGSGSLGSKYQGQRGPTPSKGYLNFSSEQDSD
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.