PharMolix/UniProtQA huggingface dataset:
Protein: CDPKM_ORYSJ
Sequence: MGGCSSAFAVSTRMIRFSRGRVPAAILPVTSNDEPCCSCSPENNNKNNDGGGGGCDGGEHQKGKSWRRWQYRRCGGGGGGGGGRKNAILGDAADVKTAAGFAERYRLGAELGRGEFGVTRRCSDAATGEALACKTIRRKRLRRCRGDAEDVRREVEILRRISALGAGADSVVRLRDACEDSDGVHLVMELCEGGELFDRIFARGHYTERAAAKLARTIVGVVQLCHENGVMHRDLKPENFLFANKSEDSPLKAIDFGLSVFFKPGERFTQVVGSTYYMAPEVLNRSYGPEADVWSAGVILYILLCGVPPFWGDNDEKTVTAILQGGINFQREPWPKVSPHAKDLVSKMLDPDPSTRLTAKEVLEHPWLKNADRAPNVSLGEIVRSRLMQFSAMNKFKKKALGVVAKNLPVEEMDKYTQMFHKMDKDNSGNLTLEDLKLGLQINGHPVPETEIEMLLEAGDIDGNGTLDCEEFVTVLLHIKKMSNEEYLPKAFKFFDKDGNGFIEMEELMDALGDELGPTEQVVKDIIRDIDTDKDGRISYQEFESMMISGSDWRNASRRYSKANFSSLSRKLCKGNS
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger.
What are the official names of this protein?
Calcium-dependent protein kinase 22, OsCDPK22, OsCPK22.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: PPNP_POLNA
Sequence: MTTEKIDNISVTTQANVYFDGKCISHGITLADGTKKSVGVILPASLTFNTGAAEIMECVAGACEYKLAGSDEWVQSSAGESFSVPGNSKFDIRVAAGFEAYHYICHFA
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: CCME_POLNS
Sequence: MKPRHKRALIIIAALIAIGVAALLILNALNSNIALYVTPSEVAAGKAPQGQAFRIGGMVKDGSLKRDGLTVHFVITDLAKDIPVAYIGILPDLFKEGKGAVIQGRMNANGEFIASEVLAKHDENYMPPEAKHALDQAQKNGSAK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RBMX_PANTR
Sequence: MVEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSFESGRRGPPPPPRSRGPPRGLRGGRGGSGGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPPPKRSAPSGPVRSSSGMGGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYSDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPPTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSGRDRVGRQERGLPPSMERGYPPPRDSYSSSSRGAPRGGGRGGSRSDRGGGRSRY
What is the function of this protein?
RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes.  Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs.  Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter; may thus be involved in tumor suppression.  When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter.  Associates with nascent mRNAs transcribed by RNA polymerase II.  Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection.  Can either activate or suppress exon inclusion; acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2.  Represses the splicing of MAPT/Tau exon 10.  Binds preferentially to single-stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation; probably binds RNA as a homodimer.  Binds non-specifically to pre-mRNAs.  Also plays a role in the cytoplasmic TNFR1 trafficking pathways; promotes both the IL-1-beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment (By similarity).
What are the official names of this protein?
RNA-binding motif protein, X chromosome, Heterogeneous nuclear ribonucleoprotein G, hnRNP G.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes in numerous small granules in the nucleus. Component of ribonucleosomes (By similarity).
Protein: RL36_HYDS0
Sequence: MKVRPSVKPICPKCKIIRRKKRVMVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: GCS2_CROS8
Sequence: MPLKPFAPSEPYTLGVELELQVVSPPGFNLSQDSSTLISALESRVTAGEVKHDITESMLEIATGVCRDINQVAAEFAAMQREILACAQQYHLMISGGGTHPFQKWQRQEVCSSERYARTLELFGYLIKQATVFGQHVHVGCRNGEEAMYLLHGLSRFVPHFVALSASSPYMQGADTGFASSRLNIFSAFPDNGPAPFAADWTQFEKMYARLEGTKVVESIKDLHWDIRPSPGFGTVEVRVMDTPLTLERAINIAGFIQAISHWLLDERPYKHKAEDYLIYRFNRFQACRYGLEGTLTDVSTGEQRTIGEDILRLLDKLERYARPLNASSALEAIHRYVKNNDSDVHRIREFTADGGSLSELVRLNGEIWAA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: PHEB_PORPU
Sequence: MLDAFSRVVVNSDAKAAYVGGSDLQALKKFIADGNKRLDSVNAIVSNASCIVSDAVSGMICENPGLIAPGGNCYTNRRMAACLRDGEIILRYVSYALLAGDPSVLEDRCLNGLKETYIALGVPTNSSVRAVSIMKASAVAFITNTASQRKMATADGDCSALASEVASYCDRVAAAIS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
R-phycoerythrin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the periphery of the phycobilisome rod.
Protein: MUTS_BRADU
Sequence: MTMQQPIPVPPPDETPAPQAEAAARVTPMMEQYLEIKAAHQGLLLFYRMGDFYELFFEDAEIASKTLGIVLTKRGKHQGADIPMCGVPVERAEDYLHRLISAGHRVAVCEQTEDPAAAKARGNKSVVRRGVVRLVTPGTLTEDTLLDARANNYLLAIARARSSTGGDRFGLAWIDISTAEFMVTECSGGELAATLARINPNEAIVTDALYNDNELGQTLRELPAVTPLTRDVFDGATAEKRLCDYFAVATMDGLAQLTRLEATAASAAVTYVDRTQVGRHPPLSPPAREASGATMAIDPATRANLELTRTLAGERRGSLLDAIDCTVTSAGSRLLAQRLAAPLTDAPAIARRLDAVGAFVADSAAREDIRSILRGAPDMSRALARLSVGRGGPRDLAGLRDGIIAADQVLARLGELDQPPQEIAAVMAALTRPSRELAAEFATALDEQLPLIKRDGGFVRQGYEPALDEARNLRDASRLVVASMQARYADDTGVKGLKIRHNNVLGYFVEVTAQHGDKLMSAPLNATFIHRQTLAGQIRFTTSELGEIEAKIANAGDRALGLELEIFERLCAKALEISDDLRAAAQGFALLDVATSLAKLAVDENYVRPEVDSSLGFAIEAGRHPVVEQALKRNGEPFIANACDLSPAPAQKSGQLWLLTGPNMAGKSTFLRQNALIALLAQIGSFVPATRARIGIIDRLFSRVGAADDLARGRSTFMVEMVETAAILNQAGERALVILDEIGRGTATFDGLSIAWAAIEHLHESNRCRTLFATHYHELTALSAKLPRMFNATVRVKEWQGNVVFLHEVLPGSADRSYGIQVAKLAGLPPAVITRAKSVLAKLEAQDRGQTARALADDLPLFAVPSRAAAEAAPPSEAELLMDAVKALHPDEMSPREALDALYALKAKLPKQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MNMG_STRP2
Sequence: MIYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEMLAFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQADKELYSKEMRKTVENQENLTLRQTMIDEILVEDGKAVGVRTATHQEYAAKAVIVTTGTALRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTEIQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGLENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGINAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMRLTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTDAVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMKRMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEGKNRSISKTLQKSK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REP_WDVS
Sequence: MASSSAPRFRVYSKYLFLTYPECTLEPQYALDSLRTLLNKYEPLYIAAVRELHEDGSPHLHVLVQNKLRASITNPNALNLRMDTSPFSIFHPNIQAAKDCNQVRDYITKEVDSDVNTAEWGTFVAVSTPGRKDRDADMKQIIESSSSREEFLSMVCNRFPFEWSIRLKDFEYTARHLFPDPVATYTPEFPTESLICHETIESWKNEHLYSESPGRHKSIYICGPTRTGKTSWARSLGTHNYYNSLVDFTTYDVNAKYNIIDDIPFKFTPNWKCFVGAQRDFTVNPKYGKRKVIRGGIPCIILVNPDEDWLKDMTPEQSDYMYSNTVVHYMYEGETFINYSFASGEDVTASQ
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities.  Acts as an inhibitor of C-sense gene transcription (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: KAIA_SYNE7
Sequence: MLSQIAICIWVESTAILQDCQRALSADRYQLQVCESGEMLLEYAQTHRDQIDCLILVAANPSFRAVVQQLCFEGVVVPAIVVGDRDSEDPDEPAKEQLYHSAELHLGIHQLEQLPYQVDAALAEFLRLAPVETMADHIMLMGANHDPELSSQQRDLAQRLQERLGYLGVYYKRDPDRFLRNLPAYESQKLHQAMQTSYREIVLSYFSPNSNLNQSIDNFVNMAFFADVPVTKVVEIHMELMDEFAKKLRVEGRSEDILLDYRLTLIDVIAHLCEMYRRSIPRET
What is the function of this protein?
KaiA binds oxidized quinones via its N-terminal PsR domain and is able to sense redox signals directly; quinone analog DBMIB (2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone) blocks KaiA stimulation of KaiC phosphorylation (PubMed:20231482).  The homodimer binds up to 8 quinones in the crystal structure, 3 in the PsR domain and 1 via the C-terminal helical bundle.  Binding of oxidized quinone to the KaiA C-terminal domain reduces the phosphorylation of KaiC slightly; quinones may interact in a complex manner with KaiA to mediate clock input (PubMed:23020633).
What are the official names of this protein?
Circadian clock oscillator protein KaiA.
What is the protein family that this protein belongs to?
Belongs to the KaiA family.
Protein: CE027_HUMAN
Sequence: MTPCLESFCQRAKDCKQNIPLPFLIQDWPLSESKPQGQDFWTPQPLQAAAPSHEFQQVALHPARTRLASRPQGGRLMSSREVGLRAPRCSCGKRKR
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC01554, Protein FIS.
Protein: MOBA_SYNP6
Sequence: MNFAALILAGGSSRRMGQDKALLRLNGEPLLIRTSRIAAAVCDSVWICSPEPDRYQSLLSQPVQWLTEPQPTGPQGPLTALAWALPQIDADWILLLACDLPRLAIAPLQAWRQQVELLPEDCRAAIARTEQGWEPLIGFYRPAIAPTIAPWLSQGRRDFQGWLATVAVQELPLSDRDWLVNCNTPTDWQALQLS
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_SWPVK
Sequence: MSLYVKCVKLSNNAIIPNRSMSGSAGYDLYSAYSYTVKPYNRILVRTDICLMIPDKCYGRISPRSGLSLNYNIDIGGGVIDSDYRGEIGIVFINNGCSDFNIKVGDRIAQIIFERVEYPIMEEVKCLEDTERGNSGFGSSGM
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: Y4821_DICDI
Sequence: MPIKESFKRIKSDHQNQNQDQINYVDENVKENLSTYYLVKRISFEYSFKEFLNSDQYLSIDTSIIFSKNIMNALYYLHSNNIIYADLKPSNILIDSKGIFKLNSINNSILIENNNNNNNNNNNNNNNNNNNNNNNQQIMITSRQQIFNLYNNNIDNDNNNNINESIYYLSPEVLKGYTYSFSSDIWSFGVLLFKCITGYYPFYSNDATKLIESIIYDNYLDPIIRLPSDNNDLIQQQHFNDLISKILEKNPQKRITWPKLFIHPFFKNQQTQQVNEIINKSSNTTLQLLNKSSSSSSSSSSSSSSSSSSSSSSSLSFQQQQQPNNISSPNLENQVIRLNKVKIPPLNISQTNSLNDFSNLIENNNFTRLISEFDHSIDFEASPIISPNRPSSPPLSSLSSCSSSSSSSVPIIFNKTIKDLQLLINNNNNNNNNNNNNNNNNNNNNNNNNYQEIIEYFNFISKFIKTKTTIITKLTLLNYLIDLLLLSNNQYSSIIEKLLIIINEHTILIKQLVQQIKISNDTIIKVKIIHLLGIIIGKSNNLSINSKDSIIQLLEYLNNEISSFNNNNNIQLSLKRKLVSTFGEILFYFSTLDEITLSTKWGILSLEKYINTLLNLFLINDSSSPSSSPPPSSSSSSSSPSSPSSTSPSLLSSIPNPSLFPQISLSSIITTNKAIDKTILLYLIKTFDNLLITRPIYIKYFSIKSKQLLNQFLKYIKDDNNLEDELNNNIKISSSSAFYRIIKQQPILSLSLIDNCNESVMINMIDLNQHWRVQISFLNILFILITINNNFIDDNNNINNINNNNNEFIKKFLEKLYNHYINQKNQINPIVFKKSFIFYSILKDFNNNNFIKIN
What are the official names of this protein?
Probable inactive serine/threonine-protein kinase DDB_G0274821.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS3_ACIAC
Sequence: MGQKIHPTGFRLAVSRNWASRWYANNRDFAGMLAEDIKVREYLKAKLKNAAVSRILIERPAKNARITIYSARPGVVIGKKGEDIENLKKELASRLGVPVAVNIEEVRKPEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARTEWYREGRVPLHTLRADIDYGTSEAFTTYGVIGLKVWVYKGDTLGRNDLPAVETPRPEEERRPRGPRRDGRPGGDRAGAGRGPRRPMGGNAAPADGSDKPAGAGGTDATAVKRVRKVDAPATAADGKGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: FTHS_DESPS
Sequence: MDLTKEEILPYGHHVAKLDYRKILDRCADRPDGKYIDVTAITPTPLGEGKSTSVMGLVQGLGKRDKSVVGAIRQPSGGPTMNIKGSAAGGGRSQCIPLNEFSLGLTGDINSIMNAHNLGMVALTARMQHEANYTDAQLAQRNLKRLDIHPKKIQFSWIIDFCAQALRNITIGIGGKMDGPTIQSSFAIAVSSELMAILAIANDLADMRARIAKVVVAYDKQDRPITTADLEVDGAMTAWMVQAINPNLMQTLEGQPVLVHAGPFANIAIGQSSVIADRVGLKIAGYNVTESGFGADIGFEKFWNLKCRFSGNKPNCAVIVATIRALKCHGGAPIPVPGKPMPEEYAKENVGWVEEGCKNLLHHINTVKKAGINPVVCINAFYTDRPNEIKAVKRICEHAGARVAVSTHWEHGGDGALEFADAVIDACEEKNDFKFLYELDTPLEKRIELIAKEVYGADGVSYTPEARTKLTQLAKDPEMAELGTCMVKTHLSLSHDPKLKGVPKGWTLPIRDILTYKGAGFVVPVAGAISLMPGTGSDPAYRRVDVDLQTGRVKGVF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: BETB_VIBPA
Sequence: MEMKTHYIDGAMYIGCSEEHFTTYNPANGEPLANIKQANQSDMEAAIESAKRGFEVWSAMTAIERSRILNKAVAILRERNDELAALEVADTGKPIQEAIAVDITTGADVIEYYAGLAPSLQGEQQPLNENQFFYTRREPLGICAGIGAWNYPIQIAMWKSAPALAAGNAMIFKPSEETPLTALKLAEIYSEAGLPDGVFNVVQGDYRVGQMLTAHPDIAKVSFTGESGTGKVVMGDSAKTLKQVTMELGGKSPLIVFDDAKLDDAVSAAMVANFYTQGEVCTNGTRVFVHESIYDDFVAQLKTRTEKLVVGDPLDENTQIGALISKEHESKVLSAIESAKASGATLLTGGYKVTDNGLQNGNFVAPTVFIDCDDSMSHVQQEIFGPVMSVLKFSEEAEVIERANDTDYGLAAGVFTQNLSRAHRVIHKIQAGICWVNAWGDSPAEMPVGGYKQSGIGRENGVETLKHYTQTKSVLVQLSDFESPYA
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: DBP5_NEUCR
Sequence: MADLASRITKPDEAPAAAPEAAPVSAPASEEPKAPENETSIEESQSNLVKNEYEVEIKLSDLQNDTESPLYSVSSFDELGLPEAVNRGLLAINFKKPSKVQEKCLPLMLSDPPRNMIAQSQSGTGKTAAFVLTVLSRIDLSKPHQPQALLLAPSRELARQIQTVVQTIGQFCENLIVEAAIPGAISRETGVRGSVVVGTPGTVMDLVKRRQFDISQLKVLVIDEADNMLDQQGLGDQCVRVKNMLPKTIQILLFSATFPDKVLRFAERFAPNANQMKLKHKELTVKGISQMFMDCPTEKDKYDILCKLYGLMTIGSSVIFVRTRETANEIQKRMEADGHKVSALHGAYEGQSRDVLLDEFRSGRSKVLITTNVLARGIDVSSVSMVINYDIPMKGPGEREPDAETYLHRIGRTGRFGRVGVSISFVHDRRSFEALSQIAQFYGIDLIQLNPNDLDDTERKVQEVIKSSRAQAEYVPSATDSAV
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp-5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: CBPA_SALA4
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQLWQHRNDPQFNRQFQQHEGQPYNAEDFDDIFSSIFGQHGRHSHHRHAARGHDIEIEVAVFLEETLEEHQRTISYSVPVYNAFGLVEREIPKTLNVKIPAGVSNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVNQDLEVVLPLAPWEAALGAKVSVPTLKERILLTIPPGSQAGQRLRIKGKGLASKKHTGDLYAIIKIVMPPKPDEKTAALWQQLADAQSSFDPRQQWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FXYD5_HUMAN
Sequence: MSPSGRLCLLTIVGLILPTRGQTLKDTTSSSSADSTIMDIQVPTRAPDAVYTELQPTSPTPTWPADETPQPQTQTQQLEGTDGPLVTDPETHKSTKAAHPTDDTTTLSERPSPSTDVQTDPQTLKPSGFHEDDPFFYDEHTLRKRGLLVAAVLFITGIIILTSGKCRQLSRLCRNRCR
What is the function of this protein?
Involved in down-regulation of E-cadherin which results in reduced cell adhesion.  Promotes metastasis.
What are the official names of this protein?
FXYD domain-containing ion transport regulator 5, Dysadherin.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: EPT1_MOUSE
Sequence: MAGYEYVSPEQLSGFDKYKYSALDTNPLSLYIMHPFWNTIVKVFPTWLAPNLITFSGFMLLVFNFLLLTYFDPDFYASAPGHKHVPDWVWIVVGILNFAAYTLDGVDGKQARRTNSSTPLGELFDHGLDSWSCVYFVVTVYSIFGRGPTGVSVFVLYLLLWVVLFSFILSHWEKYNTGVLFLPWGYDISQVTISFVYIVTAVVGVEAWYEPFLFNFLYRDLFTAMIIGCALCVTLPMSLLNFFRSYKSNTLKHKSVYEAMVPFFSPCLLFTLCTVWILWSPSDILEIHPRIFYFMVGTAFANITCQLIVCQMSSTRCPTLNWLLLPLLLVVAAVIVGAATSRLESALLYTLTAAFTLAHIHYGVQVVKQLSRHFQIYPFSLRKPNSDULGMEEQNIGL
What is the function of this protein?
Ethanolaminephosphotransferase that catalyzes the transfer of phosphoethanolamine/PE from CDP-ethanolamine to lipid acceptors, the final step in the synthesis of PE via the 'Kennedy' pathway.  PE is the second most abundant phospholipid of membranes in mammals and is involved in various membrane-related cellular processes.  The enzyme is critical for the synthesis of several PE species and could also catalyze the synthesis of ether-linked phospholipids like plasmanyl- and plasmenyl-PE which could explain it is required for proper myelination and neurodevelopment.
What are the official names of this protein?
Ethanolaminephosphotransferase 1, Selenoprotein I, SelI.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y2093_SHIFL
Sequence: MSLNILIIYFLGMVGQFNKIAIFLIFTVCWVLSIIKRQQFRWLAINNIEFSTLFVILFLVLIFVVTLLSSLRAPGDWDDTMYHLPLARSLVEHHAIVVEQYLRFPLFPQNADLLMALGLQLGDVRLAQFLANICFFVIACGLVGCSWEITKTYYPGIIATILLFTINPLKDHLGYAYIDLTLSLFCCSQYSYIYSLRKQ
What are the official names of this protein?
Uncharacterized protein SF2093/S2215, ORF11X6.
Protein: GLGC_SALA4
Sequence: MVSLEKNDRVMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCLNSGIRRIGVITQYQSHTLVQHIQRGWSLFSEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIKEATAFGVMAVDESDKIIDFVEKPANPPAMPGDASKALASMGIYVFDADYLYELLAADDKDDASSHDFGKDIIPKITREGMAYAHPFPLSCVQSDPQAEPYWRDVGTLEAYWKANLDLASVTPELDMYDQNWPIRTHMESLPPAKFVQDRSGSHGMTLNSLVSGGCIISGSVVVQSVLFPRVRINSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACIIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLQVKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: MPPB_MOUSE
Sequence: MAAAALSRTLLPEARRRLWGFTRRLPLRRAAAQPLYFGGDRLRSTQAAPQVVLNVPETQVTCLENGLRVASENSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSRDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSINRKDLVDYITTHYKGPRIVLAAAGGVCHNELLELAKFHFGDSLCSHKGAIPALPPCKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCEQATVADMLHVVQNEWKRLCTDVTESEVARAKNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVDAETVRRVCTKYIHDKSPAIAALGPIERLPDFNQICSNMRWIRD
What is the function of this protein?
Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (By similarity).  Preferentially, cleaves after an arginine at position P2 (By similarity).  Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis (By similarity).
What are the official names of this protein?
Mitochondrial-processing peptidase subunit beta, Beta-MPP, P-52.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL33_HELPS
Sequence: MKVKIGLKCSDCEDINYSTTKNAKTNTEKLELKKFCPRENKHTLHKEIKLKS
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.