PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_SHEAM
Sequence: MKDLLKFLKQQGKTEEFEGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESYVVIEPGMTSLERGQMLTEENYLDALEEYGDEFEAKMGAEAVLDLLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLIEAFYTSGNKPEWMILKVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYISRERVNGRGEAMAFESVAEAEKAYRVGAAELHARVKVRITETIIGENGERTKQRRIVDTTVGRAILSQILPAGLSFDLVNQDMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFQYATISGASVGINDMVIPEEKYSLVADAEAEVIEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSSETVINRHGEEEKQKSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVIIEDDCGATEGLSMKPLIEGGDVVEPLRERVLGRVVAEDVMYPGTDEVLAPRNTLLDEAWCDKLEQHSVDEVQVRSVITCETDFGVCAKCYGRDLARGHIINMGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENSVQVKNAGTLKLHNAKYVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLDTKEGAEVNAGQIIANWDPHTHPIITEVAGSIKFVDMIDGVTITRQTDELTGLSSIVVLDVGQRTSAGKEMRPAVRLVDDNGNDLTIPGTDVPAQYFLPGNAIVNLDDNAKISVGDALARIPQESSKTRDITGGLPRVADLFEARRPKEPAILAEISGTISFGKETKGKRRLVITPNDGGDAYEEMIPKWRNLNVFEGEKVERGEVIADGPESAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCIITQAGDSEFLEGEQVEVARVKIANRDLEAAGKQPAKFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAGTGFAYHKNRAKARASGEETAAPTITASEAEQNLADLLNLAGSQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: KAX6V_HETLA
Sequence: ISCTGSKQCYDPCKKKTGCPNAKCMNKSCXCYGC
What is the function of this protein?
Binds to voltage-gated potassium channels Kv1. 3/KCNA3 (IC(50)=0. 48 uM) and Kv1. 1/KCNA1 (IC(50)=6. 7 uM) and inhibits channel activity.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 6 hetlaxin.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL15_PSEU2
Sequence: MKLNDLSPAPGSRREKHRPGRGIGSGLGKTGGRGHKGQSSRSGGTIAPGFEGGQQPLHRRLPKFGFVSLKAMDRAEVRLSELAKVEGDIVTVQSLKDANVINQNVQRVKIMLSGEVTRAVTIKGIAATKGARAAIEAAGGKFEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: LOL4_ORYSJ
Sequence: MQDQLICSGCRRVVQYRRGVAGVCCPGCNTLTAVNPSAVADMSELICSGCPTLLFYNRGASNIRCPSCNRLNSTRSANQIAHLTCGQCRTTLMHPPGASTVQCATCRYVNHVRDARPQTVLVENPKTLDDKGKLVSNVVVGVTSWKR
What is the function of this protein?
Putative zinc finger that may be involved in programmed cell death and defense response.
What are the official names of this protein?
Protein LOL4, Protein LSD ONE LIKE 4, OsLOL4, Putative zinc finger LOL4.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS7_XANOP
Sequence: MTPILFVDRDGTLITEPADYQIDAYEKLRFVDHVIPAMLKLRDAGYQFVIVSNQDGLGSESFPRASFDGPNNLMLQIFASQGIEFREVLIDCSWPSDNAPTRKPGVGLMVPYLQDRTIDWARSAMVGDRITDIQFAQNLNIRGFQLRTDEFGGEWDWPGIAHELADAPRRAVVQRNTKETRIRVELDLDRVAEPKTATGLPFFDHMLEQIGKHGGFALDIRAEGDLHIDEHHTIEDTGLALGQALREALGDKRGIGRYGFDPESSPWQVAGDTAQHGFTLPMDETIASAALDFSGRPYFVFDGQFKRDRLGDMPTELVPHFFRSICDASGVNLHLTVRGENDHHKVEACFKALARALRQAIRREGSALPTTKGAL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPHA3_DANRE
Sequence: MALFRIYSFLAPFHILVLCQALRNYPDNEVTLLDSMSAPGDLGWEAYPSEGWEEISVMDERNIPMRTYQVCNVMEANQNNWLRTGLIQREGAQRVYVEIKFTLRDCNSLPGVPGTCKETFNVYYHESNNAVAAPLRHIRESQYIKIDTIAADESFTQTDVGDRVMKLNTEVRDISGLSKRGLYLAFQDLGACIALVSVRVFYKRCPLAVLNLARFPDTVTGGDSALVEVRGTCVEDAEELEGPRMFCSADGGWLVPIGRCVCRPGFEEVDGHCQPCRSGFYKASAMDAYCVKCPPHSYSHQDKASECVCERGFYRAESDPRSMACTRPPSAPGNPISMVNETAVTLEWSPPRDSGGRGDVSYSVHCRKCSGETGASERCVPCGSGAHFNPRQFGLTHPRVLVTELQPHTNYTFSVEALNGVSDLSPSPRQLVSVNVTTSQTVSVILKERKGTDSVTLAWQGPEPVDGTVVEYEVTYYEKNQQDQNYTVLKTKSNSMTVDGLKPGTTYIFRVRARTDGGYGNYKGEIELETSHEDMLAVGDPNQQTILAISVAGGAVLLVLLVACFIVSGRRCGYIKAKQDPEEEKMQFQHGRVKLPETRTYIHPHTYEDPNQAVRDFAKEIEVSNIRIERVIGAGEFGEVCSGRLRLPSKREIQVAIKSLKAGYSEHQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKPVMIVTEYMENGSLDTFLKKHDGQFTVIQLLGMLRGIAAGMQYLSEMNYVHRDLAARNILVNRNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAITYRKFTSASDVWSYGIVMWEVISYGERPYWEMSNQDVIKAVDEGYRLPAPMDCPVVLHQLMLDCWEKNRSDRPKFGQIVNTLDRLIRNPSSLKQLANSAVWEDPVTPEAAVNTVEDWLDLIKMGQYKEHFSSAGYVTLDSVLYVSSSELDKMGVELAGHQKKILSSIQCLQAHHGTQVQV
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Highly promiscuous for ephrin-A ligands it binds preferentially efna5.  Upon activation by efna5 regulates cell-cell adhesion, cytoskeletal organization and cell migration.  Plays a role in cardiac cells migration and differentiation probably through activation by efna1.  Involved in the retinotectal mapping of neurons.  May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development (By similarity).
What are the official names of this protein?
Ephrin type-A receptor 3, EPH-like kinase 1, Tyrosine-protein kinase receptor ZEK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Y1491_CALS4
Sequence: MEKIAIVTDSLSDIPEDLIKTYGIFVVPLTINIDGKSYKDGVDIKKEEFYKLLREGKMPTTTQASPVEFMEVFEDLLKSFDYVIAIILTSKFSGTYQSAVIARDMVDKNRIEVIDSRHFTLGNGMLVLKAARMAVEGASKEEIVSTVYETIPRIRGIMVFDSLDYLYRGGRLSRTQSIIGGILNVKPILTNEDGELKVIDKVRGQKKAIRWIIDYMKNTGIDFAEREVGLIHTDKEEFLNEIEAALRSELEITRFIRSQAGCGIGTHAGPDAAGVFFEEK
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein TTE1491.
Protein: CLPS_SHEPA
Sequence: MSRTENIEHVEESVESELKQPSMYKVILNNDDYTPMDFVIEILQLFFKKDEQQATEIMLAIHHKGKGICGIYPFGIAETKVAQVNQFARQNQHPLLCSLEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RR7_GUITH
Sequence: MSRRSTTKKKLALPDPIYNSRLVNMLTVRILKEGKKHLAQRIIYNAFDIIKQRTGEDAILVFESAIKKVTPLVEVKARRIGGSTYQVPMEVRAFRGTNLALRWITKYARERAGKSMSMKLANEIMDAANETGSSIRKREEIHRMAEANKAFAHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDHL_PROMT
Sequence: MSLISIVCLIPFGLIGAVNPIITLSAYAVLGGMYLLVVPLFLFYWMNNRWNVMGKLERLFIYGLVFLFFPGMILFAPFLNLRMNGKEGS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit L, NAD(P)H dehydrogenase I subunit L, NDH-1 subunit L, NDH-L.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhL subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RL32_STRPM
Sequence: MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSLKGYYKGRKIAKANEAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: GLSA_AGRFC
Sequence: MQDIQGIVDSIYDSMLPRLGEGKVADYIPELAKVDPNQFGIAITTVDGTTYTAGNALVPFSIQSISKVFMLTLALGKAGETVWNRVGREPSGSSFNSIVQLEHEHGIPRNPFVNAGAIVVTDIVLSGHQPREAIGELLRFVRYLADDDTISIDDTVAKSEQATGFRNFALANFMRSFGNLHHPVEHTLGVYFHQCALSMTCAQLSRAGLFLANRGRNPLSGHTVVSDRRARRINALMLTCGHYDGSGDFAYHVGLPGKSGVGGGIMAVAPGNASIAVWSPGLNKVGNSALGSQALELLATKTGWSVFGA
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: PHGR1_HUMAN
Sequence: MDPGPKGHCHCGGHGHPPGHCGPPPGHGPGPCGPPPHHGPGPCGPPPGHGPGPCGPPPHHGPGPCGPPPGHGPGHPPPGPHH
What are the official names of this protein?
Proline, histidine and glycine-rich protein 1.
Protein: RL30_STRMK
Sequence: MANESNKTVKVRLVRGLRGTQSRHRLSVRALGLNKLNDVRELKDSPQVRGLINKVQYLVQVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RL35_BACC0
Sequence: MPKQKTHRGAAKRFKKTGSGKLKRSHAYTSHLFANKSTKAKRKLRKAGVVSAGDFKRIRQMLDNLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ODFP1_RAT
Sequence: MAALSCLLDSVRRDIKKVDRELRQLRCIDEISSRCLCDLYMHPYCCCDLHPYPYCLCYSKRSRSCGLCDLYYPCCLCDYKLYCLRPSLRSLERLRRTTNRILASSCCSSNILGSVNVCGFEPDQVKVRVKDGKVCVSAERENRYDCLGSKKYSYMNICKEFSLPPCVDEKDVTYSYGLGSCVKIESPCYPCTSPCNPCNPCSPCSPCGPCGPCGPCGPCGPCGPCDPCNPCYPCGSRFSCRKMIL
What is the function of this protein?
Component of the outer dense fibers (ODF) of spermatozoa.  ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.
What are the official names of this protein?
Outer dense fiber protein 1, Protein RT7, RTS 5/1.
Protein: FADI_ERWT9
Sequence: MSKALPLLTRQGERIAITHGLRTPFARQATAFHGIPALELGRMVVSELLARSEISPDVIEQLVFGQVVQMPEAPNIAREIVLASALSVHTDAWSVSRACATSFQAVANVAESLMIGHIQAGIAGGADSSSVLPIGVSKKLARLLVDASKTRSLAQKLKLFSGLRPRDLLPVAPAVAEYSTGLRMGDSAEQMAKNHGITREQQDALALRSHQRAAHAWQQGLLNDEVMTACVPPWEQPFEQDNNVRAESKMQDYARLRPAFDRRHGTVTAANSTPLTDGAAAVILMTASRARELGIAPLGFLRSYAFSAIDVRQDMLLGPSYASPLALDRAGITLADLSLIDMHEAFAAQTLANLKMFADERFAREVLDRPRALGEVDMERFNVLGGSIAYGHPFAATGARMITQTLNELRRRGGGLGLVTACAAGGLGAAMVLEVDS
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAT1_ARATH
Sequence: MGGEERSGDGEKRGEEVVDAGSLFVLKSKGTWWHCGFHLTTSIVAPALLSLPYAFKFLGWAAGISCLVGGAAVTFYSYTLLSLTLEHHASLGNRYLRFRDMAHHILSPKWGRYYVGPIQMAVCYGVVIANALLGGQCLKAMYLVVQPNGEMKLFEFVIIFGCLLLVLAQFPSFHSLRYINSLSLLLCLLYSASAAAASIYIGKEPNAPEKDYTIVGDPETRVFGIFNAMAIIATTYGNGIIPEIQATISAPVKGKMMKGLCMCYLVVIMTFFTVAITGYWAFGKKANGLIFTNFLNAETNHYFVPTWFIFLVNLFTVLQLSAVAVVYLQPINDILESVISDPTKKEFSIRNVIPRLVVRSLFVVMATIVAAMLPFFGDVNSLLGAFGFIPLDFVLPVVFFNFTFKPSKKSFIFWINTVIAVVFSCLGVIAMVAAVRQIIIDANTYKLFADV
What is the function of this protein?
High affinity gamma-aminobutyric acid (GABA) transporter probably involved in GABA uptake into cells.  When expressed in a heterologous system (Xenopus oocytes), imports GABA, butylamine, beta- and L-Alanine, 5-aminovaleric acid, 6-aminocaproic acid and 8-aminocaprylic acid, but does not mediate the transport of proline or glycine betaine.
What are the official names of this protein?
GABA transporter 1, AtGAT1, Bidirectional amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Plasma membrane.
Protein: RBS3B_ARATH
Sequence: MASSMLSSAAVVTSPAQATMVAPFTGLKSSAAFPVTRKTNKDITSIASNGGRVSCMKVWPPIGKKKFETLSYLPDLSDVELAKEVDYLLRNKWIPCVEFELEHGFVYREHGNTPGYYDGRYWTMWKLPLFGCTDSAQVLKEVEECKKEYPGAFIRIIGFDNTRQVQCISFIAYKPPSFTEA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit 3B, chloroplastic, RuBisCO small subunit 3B.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL2_TREPA
Sequence: MALKMYRPMTAGLRGRVDLCRAELTARTPEKSLTRGKPAKAGRGAGGRISVRHRGGGHKRRYRDIDFKRDLHDIPGTVKTIEYDPNRSVNIALVFYANGQKRYILAPKGLKVGQQVVSGEKVPLEPANALPLGVIPVGFTVHNVELTIGKGGQIARSAGTRAVIAAKDGGYVMLRLPSGEARLVHRRCYATIGELGNEDHMNTALGKAGRARWRGVRPTVRGMAMNPVDHPLGGGEGRGKGRNPVTPWGQPCRGYKTRKKRRVSDRFIVSKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: OPS2_SCHGR
Sequence: MVNTTDFYPVPAAMAYESSVGLPLLGWNVPTEHLDLVHPHWRSFQVPNKYWHFGLAFVYFMLMCMSSLGNGIVLWIYATTKSIRTPSNMFIVNLALFDVLMLLEMPMLVVSSLFYQRPVGWELGCDIYAALGSVAGIGSAINNAAIAFDRYRTISCPIDGRLTQGQVLALIAGTWVWTLPFTLMPLLRIWSRFTAEGFLTTCSFDYLTDDEDTKVFVGCIFAWSYAFPLCLICCFYYRLIGAVREHEKMLRDQAKKMNVKSLQSNADTEAQSAEIRIAKVALTIFFLFLCSWTPYAVVAMIGAFGNRAALTPLSTMIPAVTAKIVSCIDPWVYAINHPRFRAEVQKRMKWLHLGEDARSSKSDTSSTATDRTVGNVSASA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Opsin-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FABZ1_ENTFA
Sequence: MKKVMTATEIMEMIPNRYPICYIDYVDEIIPNEKIIATKNVTINEEFFQGHFPGNPTMPGVLIIEALAQVGSILILKMDQFEGETAYIGGINKAKFRQKVVPGDVLKLHFEIVKLRDFVGIGKATAYVEDKKVCECELTFIVGR
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity).
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBJL_ECOBW
Sequence: MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVIGLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLMVFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TDRD5_MOUSE
Sequence: MSEQERIQDCLRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPGGDGTVILKAIPDESTKGIASLVAKQRRSHKVRNSMPKGRPSICSGRVPYRGRVPPILPAVVKSELKDLLALSPVLLSDFEKAFARRFGRSFQYMQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVSEDKQRGWPAGKVFTQPFRMKQQGSYSTGFPVMKAHFSQPISNMEPPKQVLSMAKTPTFNSVEASRLNHTEKLNQLESTFKSVIAQIGPGGTVDPELKRKIQFVVSKFPQGLFISKLLGEFELTFKEQLSPKQLGFLNVTELVGALSDILRVEFSEERQDLLVFDADLKPLPSGGPLSSVRNSCLVQPDKKTEANPWTSSLSRNSLSTVAVKKTTWDCPLKNQKEPEQKIYKKPNLVVKPLQLQVETNKPQLSLSVANHDIPPDAVRAKKLCRLPPLDTSTLVGVFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYIMPEYFIQPGHLCCVKISEDKWWYRVIIHRILGKKEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPAEEHWTARAILHFQKLCGLKPLVGVVDEYIDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCRENAPSKGFRDFNPPALYTNASSAGDMVLTDLGHPAQQHYLNEDQEILQQAQQDINDGKCISYLKSAPKELLKDSKLSSLKTHKSCEEDPRWSILQPKDLKEENEDEVPTGMPCLESVTIGDDVWDENWLPLQAKMGKAGSPASQLFTSNLVGKKQYQTGGEMAQKDWCFSTSKDIWDDSWQPLGLANDVKGGIHTPEGPIAQEKNTSTTRIQQQPDLQYPLDSSTLPKLEEFYISLIKSQQSAERSQSEPASIQTHAGRAASKALSSTPAVGDSPENHSGSVESSPGSLKKEDVSNSRAEATAKDKSQGAIDQLSFILSPQHQISQKLYIPRSTATAVLGAAARLATSRSLLHWYPSVKGGKLEAERDGVK
What is the function of this protein?
Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity.  Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.  Required for chromatoid body (CB) assembly.
What are the official names of this protein?
Tudor domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the TDRD5 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis.
Protein: ECFA2_LACJO
Sequence: MSIEFKNVDYVYAPGTPFQTQGLIDISFKIEKGSFVAIAGHTGSGKSTLMQHFDGLLLPSKGEITVAGEQINANTSSKALKAIRKKVGLVFQFPENQLFEETVLKDVMFGPLNFGFSEQKAKEQAVEWIKKVGLSEDMMDKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGQKQMFEIFKEYQRAGHTVILISHNMDDISEYADDMLVLDHGHLIKHASPQEIFSDQEWVKKHYLDEPATSRLTRELQKGGFQFSEMPLTIESLVSKVANELKKKGDMDE
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TTR52_CAEEL
Sequence: MSRFLIYFLPFFIYSGNVLSKTSCLMATGVLKCPTDPEAVKKVHIDLWDEDSLPLESDDLMGRTWSDRNGNFQVTGCASDFGPINTPDPYLYIQHNCPHRDSNATNPIQIDVIPLFLPSIVRLGNVYLDRYLEDY
What is the function of this protein?
Plays a role as a bridging molecule that mediates recognition and engulfment of apoptotic cells by cross-linking the surface-exposed phosphatidylserine with the extracellular domain of the phagocyte receptor ced-1.  Important for the generation of extracellular phosphatidylserine vesicles that promote loss of the exoplasmic leaflet from apoptotic cells in a time-dependent manner.  Required for the exposure of exoplasmic leaflet on the phagocytic cells surrounding the apoptotic cells.  Does not affect the phosphatidylserine externalization in living cells.  May play a role in mediating transfer of phosphatidylserine from phosphatidylserine vesicles to ced-1 bearing phagocytes or alternatively result in the activation of a phosphatidylserine transporter in the phagocyte that promotes phosphatidylserine externalization.
What are the official names of this protein?
Transthyretin-like protein 52.
What is the protein family that this protein belongs to?
Belongs to the nematode transthyretin-like family.
What are the subcellular locations of this protein?
Secreted. Cell surface. Note=Detected almost exclusively on the surface of apoptotic cells. In some embryos, also observed on surface of cells adjacent to dying cells.
Protein: NUDE_ECOLI
Sequence: MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRPTNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGFGANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLEDPDFNEARNVSALFLVREWLKGQGRV
What is the function of this protein?
Active on adenosine(5')triphospho(5')adenosine (Ap3A), ADP-ribose, NADH, adenosine(5')diphospho(5')adenosine (Ap2A).
What are the official names of this protein?
ADP compounds hydrolase NudE.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: SCNNB_MOUSE
Sequence: MPVKKYLLKCLHRLQKGPGYTYKELLVWYCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFKTMNFPAVTVCNSSPFQYSKVKHLLKDLDELMEAVLEKILAPEASHSNTTRTLNFTIWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTLRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEETLPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLVDKLQRKGEPYSPCTMNGSDVAIKNLYSVYNTTYSIQACLHSCFQDHMIRNCSCGHYLYPLPEGEKYCNNRDFPDWAYCYLNLQMSVTQRETCLSMCKESCNDTQYKMTISMADWPSEASEDWILHVLSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFIWITIIKLVASCKGLRRRRPQAPYTGPPPTVAELVEAHTNFGFQPDTTSCRPHGEVYPDQQTLPIPGTPPPNYDSLRLQPLDTMESDSEVEAI
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride.  Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells.  Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.  Controls the reabsorption of sodium in kidney, colon, lung and sweat glands.  Also plays a role in taste perception.
What are the official names of this protein?
Amiloride-sensitive sodium channel subunit beta, Beta-NaCH, Epithelial Na(+) channel subunit beta, Beta-ENaC, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1B subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Note=Apical membrane of epithelial cells.