PharMolix/UniProtQA huggingface dataset:
Protein: CA052_DANRE
Sequence: MSDEEKSETRNFFMGYDDLSDSSSDSESRSGPEATASSAPAEPQQSRKRAAEPLPRPDELFRSVSKPAFLYNPLNKAIDWDSRAVRAPEEPPKEFKVWKSSAVPPPQSYVTEENKKKAPAGMDMAIKWSNVYEDNGDDAPQAHRGPAHFLPEEEEEEQQPDSDDDSSSKLSKSAKKRRVETFQQKEKRKRDIGQATSDKNFVEEEKRILRQCLD
What are the official names of this protein?
UPF0690 protein C1orf52 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0690 family.
Protein: YGGE_ECOLI
Sequence: MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDIATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDGKSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKAAIDNAIHQAQELANGFHRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQAAIQFDDQVDVVFQLEPVDQQPAKTPAAQ
What are the official names of this protein?
Uncharacterized protein YggE.
Protein: MARH5_CHLAE
Sequence: MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA
What is the function of this protein?
Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission.  May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control.  Promotes ubiquitination of FIS1, DNM1L and MFN1.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF5, Membrane-associated RING finger protein 5, Membrane-associated RING-CH protein V, MARCH-V, RING-type E3 ubiquitin transferase MARCHF5.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y3406_BURVG
Sequence: MTDLSRSADTLTPARVTTAFDLPGHTTVRSLGVAQGIIVRSRSIVGSFGAALQTIFGGNITLYTSLCEKAREQAFEKMLADARKLGANAIVAMRYDSTEIGSGVTEVICYGTAVCVTPDA
What are the official names of this protein?
UPF0145 protein Bcep1808_3406.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RFRNP_METBU
Sequence: MKQRFVLDTTALTDLQTREMLEIEDLCQGMRAILDLIAESRLHLQISCYVPFPSVYKELHEFAKNNGCDDEIIAMIDTWLVKKTPDRHEVKIPSHIFHEYVSYMRERINKGMTVAEEAIREASIQCLSIESEIEDTRKVEDNTDREVIGPIVGKFRNKYRSALRYGILDSAPDIDVLLLAKELDAAVVASDYGIQKWAEQLGVRFVPANTFPMMLKEYLRHTPSDGTHQK
What is the function of this protein?
RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.
What are the official names of this protein?
RNA-free ribonuclease P, RNA-free RNase P, Protein-only RNase P.
What is the protein family that this protein belongs to?
Belongs to the HARP family.
Protein: YVAS_VACCC
Sequence: MSVISNPSKYKQSNTNKHMLEFLYSFFLCIPKLPNGSGTLCSSTRTISESNTIDVAFLNAFGMYSLR
What are the official names of this protein?
Uncharacterized 7.5 kDa protein.
Protein: EPDR2_HALAI
Sequence: MILQVVLLLACLSGAIVSTGACCPPSRFNAFQYVTIVNSTTRTRGLYYMVYDGPNERYLLTGDRLKNLYGTTRVIYDYKKGIAYNIDVQKRSCTTFPLHGKFEDQENVCVPRDAVYTGRSAYGFDQGALHSWSYEYNRTHPDGRHQNIETTVTKENCIPIVTTTISTDASGGNSLHILGYNDFYPGIRDISMLEIPSYCRA
What are the official names of this protein?
Ependymin-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ependymin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LOC1_ASPOR
Sequence: MAAKPGSTKPSGKDSNKSKPLSSASKVSKKAAKRPPPKEVKSKARTEASQLKKKKKREYTEEELDLPKLNAITPVGVVKPKGKKKGKVFVDDQEGMATILAMVNAEKEGQIESKLQKARQLEEIREAKRKEAEARQAQKKNKLEETKAAIRQKRKRKGDSNEDTKTDTTATQPNGSSSKSKGKRKSVSFA
What is the function of this protein?
Required for efficient assembly and nuclear export of the 60S ribosomal subunit.
What are the official names of this protein?
60S ribosomal subunit assembly/export protein loc1.
What is the protein family that this protein belongs to?
Belongs to the LOC1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL21_DEHM1
Sequence: MGGVNIYAIIESGGKQYKVTPGQLVEVDLFDLAEGDSIELDKVLMLNDGETVTIGSPTVPGAKVTATVAGHIKGDKVFAYRFKAKSRNHKKTGHRQLYTVLTIGEILTGGAAEKPARKPRAKKTNEVTTDGA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: MOT1_HUMAN
Sequence: MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESPV
What is the function of this protein?
Bidirectional proton-coupled monocarboxylate transporter (PubMed:12946269, PubMed:33333023, PubMed:32946811).  Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, acetate and the ketone bodies acetoacetate and beta-hydroxybutyrate, and thus contributes to the maintenance of intracellular pH (PubMed:12946269, PubMed:33333023).  The transport direction is determined by the proton motive force and the concentration gradient of the substrate monocarboxylate.  MCT1 is a major lactate exporter (By similarity).  Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis (By similarity).  Facilitates the protonated monocarboxylate form of succinate export, that its transient protonation upon muscle cell acidification in exercising muscle and ischemic heart (PubMed:32946811).  Functions via alternate outward- and inward-open conformation states.  Protonation and deprotonation of 309-Asp is essential for the conformational transition (PubMed:33333023).
What are the official names of this protein?
Monocarboxylate transporter 1, MCT 1, Solute carrier family 16 member 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MATK_METGY
Sequence: MDEFQRNENKHRSWQQFFLYPLFFREDLYAIAHDHHLDRSGSSEPTEILVSHFFSFLTVKRSIRRIRKQNNSISLLRNCDRNQFSECKKNXCSKSLLEGLTVVLEVSFAMRSKHFIEGMDGWNSIRSIHCIFPLMEDKLTHSNYISDIRVPYSIHPEILVRIFRRWIRDTPSLHLLRSILHEWQNSFSRDNLQKAIITPRENTRFSLFLWNSYVHECESFLVPLVKRFFNSQSLLYGSFPDRTHFDKKMKHIVILXXRQISTKKIWLLKDSFMHYVRYGERSLIALKGTHLEVKKWRYHLFHFWQYYFHLWFQPYRIRSLELSKTYSSFLGYFLHVKMRPLVVRAKMLDNLFITDLITNELKLIAPIRSILFFLAKEKFCDISGWPISKLSWTSLSDDDILDRFDRIWINLFHYYSGSMNQDGLYHIKYILLLSCAKTLACKHKTTIRVVREQLGSELFTKSFSKEREFISSSFSKNRLKRERIWNSEISQINPLANFWQNMQNKQIEN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMH_METB6
Sequence: MQVRIIAVGKIKERFLSEGIAEYTKRLSPYLKLSIVEIPEEHRGTRAPAGQEELAKEKEGGRILAAIPERAYVVALDLRGTEISSIELAARMHDWQLAGTNTIAFVIGGDLGLSDAVINRAAFRLSLSPLTFTHPMARLILVEQLYRACRINSGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Putative ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF2_BARBK
Sequence: MLVSNVYAQTSEALRERVENALEHADRVFPPFDFSHFCSHFFWLVISFGFFYFFIARVIVPRIGCTIEIRRDRIASDLDRAMRLKQEADTVVEIYERKLAEARLQAYAIAQKTSNEIKEKTKLERKEIETSLDKKLADAEGQIAKIRNKAVQNIGSIAEEVVPEIVKKLIGVEVSKESVSLAVKAADN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria (By similarity).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PRP38_ARATH
Sequence: MANRTDPLAKNIRGTNPQNLVEKIVRTKIYQHTFWKEQCFGLTAETLVDKAMELDHLGGTFGGSRKPTPFLCLILKMLQIQPEKEIVVEFIKNDDYKYVRILGAFYLRLTGTDVDVYRYLEPLYNDYRKVRQKLSDGKFSLTHVDEVIEELLTKDYSCDIAMPRLKKRWTLEQNGLLEPRKSVLEDDFEEEEEKEENEGIADGSEDEMDQRRKSPERERERDRDRRRDSHRHRDRDYDRDYDMDRDHDRDYERERGHGRDRDRERDRDHYRERDRDRERGRDRERDRRDRARRRSRSRSRDRKRHETDDVRDREEPKKKKEKKEKMKEDGTDHPNPEIAEMNRLRASLGMKPLRD
What is the function of this protein?
Probably required for the first pre-mRNA cleavage reaction catalyzed by the spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor 38.
What is the protein family that this protein belongs to?
Belongs to the PRP38 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURL_MYCTA
Sequence: MSPLARTPRKTSVLDTVEHAATTPDQPQPYGELGLKDDEYRRIRQILGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGETTSDEMRAAMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVCRKWEVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADRSAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGMLRIDESTGRGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGETLMLLGDTRDEFDGSVWAQVTADHLGGLPPVVDLAREKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALAGETGCRIVLPEGADPFVLLFSESAGRVLVAVPRTEESRFRGMCEARGLPAVRIGVVDQGSDAVEVQGLFAVSLAELRATSEAVLPRYFG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAZ_ORBOL
Sequence: MLTNGLISLLAIAGLATNAFAGPIRKVSNAGAAGAIADKYIVVLKKGLSDSAVSKHTNRISSFHSNVARDLTGARAHGVGRKFRFSSTGFNGYVGGFDKATLQEILNSPEVDYVEQDTVVTTYAEQTDSTWGLDRISHEDYSAPYTYEYDETAAGAGTTVYVIDTGIRISHDEFQTVNGSSRATWGFNSVDKTDSDGNGHGTHCAGTIAGKTYGVSKKAKVVAVKVLSAGGSGSTAGVVSGMNWVAENATPNFSVASMSLGGSKSTALNAAVDCIFNAGITIVVAAGNENQDAKNVSPASAPNAITVGAIDSSNKIASLSNWGTLIDVFAPGVGVLSSWATSDKETKTISGTSMACPHVAGLAAYYISASEGGADPATITDKITSSRRQWSGHREHPWLPKQDRLQRICLSTHSPKTNHQVTIVAS
What is the function of this protein?
Hydrolyzes gelatin, casein, the chromogenic substrate azocoll and the cuticle of the nematode P. redivivus.  Immobilizes P. redivivus.
What are the official names of this protein?
Cuticle-degrading serine protease, Neutral serine protease Aoz1, Aoz, PII.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: D7OMT_GLYEC
Sequence: MASSINGRKPSEIFQGQALLYRHIYAFIDSMCLKWIVELDIPNIIHNHGKPITVSELVSILKVPQTKAGNVQRIMRYMAHNGFFERVRIQEEQEENEAYALTAASELLVKGSELCLAPMVECVLDPTLSGSYHQLKKWIYEEDLTLFGVSLGSHFWEFLNENPEYNKSFNDAMASDSQMINLALRDCNSGFEGVESIVDVGGGIGTTAKIICDTFPNLKCIVFDRPKVVENLSGTNNLSYVGGDMFQSVPKADAVLLKWILHNWTDNDCRRILEKCKEAVSSDGEKGKVIIIEMVINENQDEHEITGTKLLMDVNMACLNGKERSEEEWKKLFIEAGFRDYKISPLTGFLSLIEVYP
What is the function of this protein?
7-O-methyltransferase involved in the biosynthesis of isoformononetin.  Can use daidzein as substrate, but not medicarpin or 2,7,4'-trihydroxyisoflavanone.
What are the official names of this protein?
Isoflavone 7-O-methyltransferase, Daidzein 7-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: TERM_ADE07
Sequence: MNYFMPLRNIWNRVREFPRASTTASGITWMSRYIYGYHRLMLEDLAPGAPATERWPLYRQPSPHFLIGYQYLVRTCNDYIFDTRAYSRLKYTELVRPGHQTVNWSVMANCSYTINTGAYHRFVDFDDFQATLTQVQQAILAERVVAELALVQPMRGFGITRMHGRAGEEEVPVERLMQDYYKDLARCQDDAWGMAHRLRIQQAGPKDLVLLATIRRLKTAYFNFITSSIVSPSQEGEGEERENPDRASSRPRPQETVLSLPCDCDWLDAFVERFSDPVDLETIRSLRGVPTGQLIKCIISAVSLPNGEPPSHHFREMRGGVFTLRPRENGRAVTETMRRRRGEVIERFIDRLPVRRRRRRVPPPPAAPPEEEEMLVEEEEIEEEILGAFEREVRTTIAELIRLLEEELTVSARNSQFFNFAVNFYEAMERLEALGDVSEMPLRRWIMYFFVTEHIATTLNYLFQRLCNYAVFTRHVELNLAQVVMRARDPVGAVVYSRVWNEAGMNAFSQLIGRISNDLAATVERAGRGDLQEEEIEQFMAEIAYQDNSGDVQEILRQAAVNDTEIDSVELSFRFKLTGPVAFTQRRQIQDVNRRVVAHASLLRAQYQNLPARGADVPLPAMPPGPEPPLPPGARPRHRF
What is the function of this protein?
Protein covalently bound to the viral DNA that acts as a primer for viral genomic replication by DNA strand displacement.  Assembles on the viral origin of replication in an initiation complex with viral polymerase, DBP, host NFIA and host POU2F1/OCT1.  During initiation, the polymerase covalently couples the first dCTP with Ser-580 of pTP.  The terminal protein stimulates the template activity over 20 fold compared to protein-free templates.  Neo-synthesized viral genomes are linked to two preterminal proteins, one for each 5' end.  These new genomes are encapsidated in the nucleus, and during capsid maturation by viral protease, preterminal protein is first cleaved into intermediary (iTP), then into mature TP.  May play a role in host nuclear matrix localization of genomic DNA.
What are the official names of this protein?
Preterminal protein, pTP, Bellett protein, Precursor terminal protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae terminal protein family.
What are the subcellular locations of this protein?
Host nucleus matrix.
Protein: RPOZ_ANADF
Sequence: MARVTVEDCLPLVDNRFALVLLATKRTRQLMAGARPLQGHAKNKAPVVALREIATGKVRFDRSVRDALSGKFDKEKSTIPAGQTRTLR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: 6PGD_STAAS
Sequence: MTQQIGVIGLAVMGKNLAWNIESRGYSVSVFNRSSEKTDLMVEESKGKNIHPTYSLEEFVNSLEKPRKILLMVQAGKATDATIDSLLPLLDDGDILIDGGNTNYQDTIRRNKALAQSAINFIGMGVSGGEIGALTGPSLMPGGQEEAYNKVADILDAIAAKAKDGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIAESYAMMKELLGMSHEDIAQTFKDWNAGELESYLIEITGDIFMKLDENKEALVEKILDTAGQKGTGKWTSINALELGIPLTIITESVFARFISSIKEERVNASKELNGPKASFDGDKKDFLEKIRKALYMSKICSYAQGFAQMRKASEDNEWNLKLGDLAMIWREGCIIRAQFLQKIKDAYDNNPGLQNLLLDPYFKNIVTEYQDALRDVVATGVQNGVPTPGFSSSINYYDSYRAADLPANLIQAQRDYFGAHTYERKDKEGVFHTQWIEE
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: PORA_ORYSJ
Sequence: MALQVQAALLPSALSVPKKGNLSAVVKEPGFLSVSQKAKKPSLVVRAVATPAAPVASPGAGTSKADGKKTLRQGVVVITGASSGLGLAAAKALAETGKWHVVMACRDFLKAATAAKAAGMAAGSYTVMHLDLASLDSVRQFVDNFRRSGMPLDALVCNAAIYRPTARQPTFTADGYEMSVGVNHLGHFLLARLMLDDLKKSDYPSRRLIILGSITGNTNTLAGNVPPKAGLGDLRGLAGGLRGQNGSAMIDGAESFDGAKAYKDSKICNMLTMQEFHRRFHEETGITFASLYPGCIATTGLFREHIPLFRLLFPPFQRFVTKGFVSEAESGKRLAQVVGDPSLTKSGVYWSWNKDSASFENQLSQEASDPEKARKLWDLSEKLVGLV
What is the function of this protein?
Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
What are the official names of this protein?
Protochlorophyllide reductase A, chloroplastic, PCR A, NADPH-protochlorophyllide oxidoreductase A, POR A.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SAR1_LODEL
Sequence: MWIFDWFQDILASLGLWNKHAKLLFLGLDNAGKTTLLHMLKNDRLATLQPTLHPTSEELAIGSVRFTTFDLGGHQQARRLWKDYFPEVNGIVFLVDAADSERFAESKAELESLFKIEELSQVPFVILGNKIDVPTAVGEMELKNALGLYNTTGKDTGKLPEGQRPIEVFMVSVVMRSGYGDAFKWLSQYI
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  SAR1 controls the coat assembly in a stepwise manner.  Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex.  These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase SAR1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VP6_ROTLP
Sequence: MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIVTMNGNEFQTGGIGNLPIRNWNFDFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCMDEMVRESQRNGIAPQSESLRKLSGIKFKRINFDNSSEYIENWNLQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANTQQFEHIVQLRRVLTTATITLLPDAERFSFPRVINSADGATTWYFNPVILRPNNVEVEFLLNGQIINTYQARFGTIIARNFDTIRLSFQLMRPPNMTPAVAALFPNAQPFEHHATVGLTLRIESAVCESVLADASETMLANVTSVRQEYAIPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLIK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: H2Z01_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLFKCSVSCEIEKEGNRDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1r, U4-TRTX-Hhn1r, Hainantoxin-II-26, HNTX-II-26.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLYC_HUMAN
Sequence: MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
What is the function of this protein?
Interconversion of serine and glycine (PubMed:8505317, PubMed:24698160).
What are the official names of this protein?
Serine hydroxymethyltransferase, cytosolic, SHMT, Glycine hydroxymethyltransferase, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
Protein: RND_NITHX
Sequence: MDLITTTAELASVCARLANYPVVTVDTEFLRETTYYPLLCVVQMASPDEAVVVDALAEGIDLKPFFDLMSNERVLKVFHAARQDIEIVWHQAGIIPHPIFDTQVAAMVLGYGDSIAYDALVERVNGHRPDKTHRFTDWSRRPLTKDQLEYAVADVTHLRDVFAALDADLKKRGRGDWVSEEMEVLTSPKTYDFHPERAWERLKTRVRKPKDLAVMMEVAAWREQEAQSRNIPRSRVLKDDAVGDIAIHAPATPERLATLRSLPKGFEKSQWGADIVAAVQRGLARDPRELPKIEKPRNNTNGAATVELLKVLLRMTSERHAVASKVIATVDDLERIAADDAADVGALRGWRRELFGEAALALKHGQLALAIEKGRVVRVERS
What is the function of this protein?
Exonuclease involved in the 3' processing of various precursor tRNAs.  Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
What are the official names of this protein?
Ribonuclease D, RNase D.
What is the protein family that this protein belongs to?
Belongs to the RNase D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_BACVZ
Sequence: MAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSVYTILRAVHKYKDSREQFEMRTHKRLIDIVNPTPQTVDALMRLDLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.