PharMolix/UniProtQA huggingface dataset:
Protein: TRUD_GEOSM
Sequence: MSIYLTAEVPGTGGVIKATPEDFLVEEIPAYLPSGQGEHCFAVLEKRGIATLEALRRLAKALGVQERDLGYAGMKDAIGITRQTISIPRVAPEKVLALEIPGITVLSASMHGNKLRLGHLKGNRFVIRVRDVAQGAAGNAEAALEIMTRRGVPNRFGVQRYGAQGNTHEIGAAMLRREFKSAVDRLIGDPAAVTDERWRLAIEAYRRGEVAESLALFPGHFRVERELLTRLVQRPDGFERAFNSVQPRMKRLYLSAFQSSLFDLVLGKRLDSFDQVNVGDIAFKHENGACFLVQDLAAEAPRAESFEISPTGPMFGCTMMESHGAQGELEREVLAAQELTLESFNLSGGLRMEGERRPLRVPIAGAEVRQDGSDLLLDFSLPRGAYATCVLSEIMKSD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: CHSY_PHAVU
Sequence: MVSVSEIRQAQRAEGPATILAIGTATPSNCVDQSTYPDYYFRITNSEHMTDLKEKFQRMCDKSMIKKRYMHLNEEILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIPQIEKPLFELVWTAQTIAPDSDGAIDGHLREVGLTFHLLKDVPGIVSKNIGKALFEAFNPLNISDYNSIFWIAHPGGPAILDQVEQKLGLKPEKMKATRDVLSDYGNMSGACVLFILDEMRRKSAEKGLKTTGEGLEWGVLFGFGPGLTIETVVLHSVAI
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 17, Naringenin-chalcone synthase 17.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: IORB_PYRAB
Sequence: MKEYNIVITGVGGQGILTAANLLGWAALRAGYKVRVGEVHGMSQRFGSVIAYVRFGEDVYGAMVPEGKADVILSFEPVEALRYINYLKKGGLVFTNARPIPPVQVSMGLASYPSMEEIRKIVEEDFGGKFLAFDAEKLAIEAGNVITTNVVLIGALTQTPGFPLSAEHVKEVIRISVPPKAVDVNMRAFELGVKAAKEMLNL
What is the function of this protein?
Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
What are the official names of this protein?
Indolepyruvate oxidoreductase subunit IorB, IOR, Indolepyruvate ferredoxin oxidoreductase subunit beta.
Protein: NATA_BACSU
Sequence: MITLTDCSRRFQDKKKVVKAVRDVSLTIEKGEVVGILGENGAGKTTMLRMIASLLEPSQGVITVDGFDTVKQPAEVKQRIGVLFGGETGLYDRMTAKENLQYFGRLYGLNRHEIKARIEDLSKRFGMRDYMNRRVGGFSKGMRQKVAIARALIHDPDIILFDEPTTGLDITSSNIFREFIQQLKREQKTILFSSHIMEEVQALCDSVIMIHSGEVIYRGALESLYESERSEDLNYIFMSKLVRGIS
What is the function of this protein?
Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion.
What are the official names of this protein?
ABC transporter ATP-binding protein NatA, ABC-type Na(+) transporter.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: IF3_WIGBR
Sequence: MLYTKKLNKKKLNTKEINIKTGKKFYSIRLHKINEEIKAKTVRLTGINGVQLGIVPIKEAIFKSLELEMDLVEISPNSNPPVCKIMNYGKFLYEKNKSNKEQKRKQKIINTKEIKFRPNTDTGDYKVKLRNLTRFLENGKKVKISLRFRGREMVHKKIGINMLNRICSDLKEISSIESFPNKIEGRQMTLILVPKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_PSEA8
Sequence: MNALTLPDIARQTTTADLPLDWVGMQGIALPVQIGGQRVAAEADAGVSLDDPQARGIHMSRLYLALAELEQGELDLSCLRAVLQRFLDSHAGLSRRAYLRLRLAPLLRRPALVSPLSGWKRYPLVLDTRLEGDDFQAEVHLELTYSSTCPCSAALARQLIQERFDQDFAGQPLDHASVLAWLGSSAGIVATPHSQRSSAHLRIGLAEDCIGLPLEELADLGESALGTAVQTAVKRADEQAFALANGQNLMFCEDAVRRLHRALQGYPQASRFSIRVVHAESLHAHDAVAESHWQRGAA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: NADE_PSESM
Sequence: MHAVQRQIAEQLKVQPPFADQNALQAEVARRVGFIKDCLQNARLKTLVLGISGGVDSLTAGLLAQRAVKELRESTGDTRYRFIAVRLPYVVQADEHEAQASVDFIEPDERHTINIGSSVKALAAEVKAFDGLPASSVDFVLGNTKARMRMVAQYTVAGAYQGLVIGTDHAAEAVMGFFTKFGDGACDLAPLSGLVKNQVRAIARHFGAPESLVEKVPTADLEDLSPGKPDEASHGVTYAEIDAFLHGEPVREEAFRIICETYAKTQHKRELPYAP
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: SCRN1_MOUSE
Sequence: MSGAPPSYSFVALPPRAKDGLVVFGKNSARPRDEVQEVVYFPAVDHDAESKVECTYISIDQVPRTHAIVISRPAWLWGAEMGANEHGVCIANEAINAREPAAETEALLGMDLVRLGLERGTTAKEALDIIVSLLDEHGQGGNYYEDAHSCHSFQSAYLLVDRDEAWVLETVGKYWAAERITEGVRCICNHLSLATKLDEEHPELRTYAQSQGWWTGDDEFNFAQVFSPADDRLDCCAGQDSLEKQEESITVQTMINILRDKASGVCIDSESFLTTASIVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKAQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAVIESDEEQGRTLRKTMLELEKQGLEAMDEILSSPEPPDPAEVGDLFYDCVDTEMKFFK
What is the function of this protein?
Regulates exocytosis in mast cells.  Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity).
What are the official names of this protein?
Secernin-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C69 family. Secernin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKR1_SCHPO
Sequence: MSYWVELWESIFTPGVTPVLAKSAHVACGALVAVFLGLYIGTKSIHCLILFFLAICLWLSLTWFLVELAHARVNNDLQMSSQSANKNDDNSNNQNPSNNKEMSDKESDSATTTQTFSVPEELLRARTTANNS
What is the function of this protein?
Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V(0).
What are the official names of this protein?
V-type ATPase assembly factor pkr1.
What is the protein family that this protein belongs to?
Belongs to the PKR1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YSCI_YERPS
Sequence: MPNIEIAQADEVIITTLEELGPAEPTTDQIMRFDAAMSEDTQGLGHSLLKEVSDIQKSFKTVKSDLHTKLAVSVDNPNDLMLMQWSLIRITIQEELIAKTAGRMSQNVETLSKGG
What is the function of this protein?
Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function.
What are the official names of this protein?
Yop proteins translocation protein I, Low calcium response locus protein O.
What is the protein family that this protein belongs to?
Belongs to the YscI/HrpB family.
Protein: PLSX_CALS4
Sequence: MKLAIDAMGGDYAPEEIIKGSLKALDHFKDIEIFLIGKEEALKGLEGKSERLKLIYASEVIENNEAPVAAIKKKKNSSMVVGLELLKKGEVEAFLSAGNTGALMAGSLLILGRIKGIKRPALAPILPTLNGATVLLDAGSNTDCDEENLFQFAVMGHVYAQKMFGIEKPRIGLFNVGTEEEKGNEVVKKAFERLKNSRLNFIGNVEGRDIPYGVCEVVVCDGFVGNAILKSMEGIAFVISQLLKEELSRNIFTKMGALLIMGGLKRITQKMDYTEYGGAPLLGISKPVIKAHGNSKAKAIFNAIKQAKNLVGNDVLRHIKEEIELTGDEISV
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: EV983_AMBCJ
Sequence: MKASFCVIASCLVVFALKGTAEDTGTEDDFDYGNTGCPFPVLGNYKSNMTKPVGCKNKCGSGYEVLNDTTPCYVIDQKVFNNMVPLRQYSKCPLGFCENGECKPNDQAEDCYKGREEQK
What is the function of this protein?
Salivary chemokine-binding protein which binds to host chemokines CCL2, CCL3 and CCL8.
What are the official names of this protein?
Evasin P983.
What are the subcellular locations of this protein?
Secreted.
Protein: IMB1_HUMAN
Sequence: MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTNKAKTLATWATKELRKLKNQA
What is the function of this protein?
Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor.  Acting autonomously, serves itself as NLS receptor.  Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.  Mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5 (PubMed:11682607).  In association with IPO7, mediates the nuclear import of H1 histone.  In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones.  In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev.  Imports SNAI1 and PRKCI into the nucleus.
What are the official names of this protein?
Importin subunit beta-1, Importin-90, Karyopherin subunit beta-1, Nuclear factor p97, Pore targeting complex 97 kDa subunit, PTAC97.
What is the protein family that this protein belongs to?
Belongs to the importin beta family. Importin beta-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus envelope.
Protein: RL29_STRPB
Sequence: MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQLEKTARLDEVKKQIARVKTVQSEMK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SPP1_MAIZE
Sequence: MDKLSGSARLMIVSDLDHTMVDHHDEENLSLLRFGALWESVYCEDSLLVFSTGRSPTLYKELRKEKPMLTPDITIMSVGTEITYGEAMVPDDGWEEYLNNKWDRNIVVAETVSFSELKLQPETEQRPHKVSFFVDKKNAQEVIKSVAERLDKCGLDAKIIYSGGQDLDILPQGAGKGQALAYLLEKLSSCGKPPNNTLVCGDSGNDAELFSIPGVHGVMVSNAQEELLQWYTENAKDNPKIIHSNERCAAGIIQAIGHFKLGPNISPRDLQFPYAKEASFKPTDAVVKFYVLYEKWRRAEVPKSDSVIKYFKNITHANGVTIHPAGLELSLHASIDALGSCYGDKQGRKYRAWVDRLFITQTGSDSWVGRFDLWESEGDVRVCSLSSLALILKAESPEGFVLTHIQKTWLNGYSSGVEQAFKL
What is the function of this protein?
Catalyzes the final step of sucrose synthesis.  Inactive with fructose 6-phosphate as substrate.
What are the official names of this protein?
Sucrose-phosphatase 1, ZmSPP1.
What is the protein family that this protein belongs to?
Belongs to the sucrose phosphatase family.
Protein: NHOA_ECOLI
Sequence: MTPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVLLPREIQLDNQSPEEKLVIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEEEKWIADVGFGGQTLTAPIRLVSDLVQTTPHGEYRLLQEGDDWVLQFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVASLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
What is the function of this protein?
Catalyzes the acetyl-CoA-dependent N-acetylation of aromatic amines, and, probably, the O-acetylation of N-hydroxyarylamines.  In vitro, catalyzes the N-acetylation of various arylamines such as aminobenzoic acid, aminophenol, aminotoluene, phenetidine, anisidine, aniline, isoniazid and 2-amino-fluorene (PubMed:10806332, PubMed:23452042).  N-hydroxyarylamine O-acetyltransferase activity has not been assayed directly, however, NhoA activity is required for the mutagenicity of nitroaromatic compounds, suggesting that it also has O-acetyltransferase activity (Probable).
What are the official names of this protein?
Arylamine N-acetyltransferase, Arylhydroxamate N,O-acetyltransferase, N-hydroxyarylamine O-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATF_METTH
Sequence: MSSNIAVVGDRDTVTGFRLGGVREGYVVETPDEAEETIRNLIRDGFSIIIVTEKIGDELREFIEETTSSSALPMIIEIPDKTGPSERETDPLRDLIKRVIGVEMVK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: AROQ_ACIB3
Sequence: MSSTILVIHGPNLNLLGKREPEVYGHLTLDNINQQLIAQAEQASITLDTFQSNWEGAIVDRIHQAQTEGVKLIIINPAALTHTSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAIGVICGLGAKGYSFALDYAIEKIQPSNPN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: QUEA_DECAR
Sequence: MSLTVDDFDFPLPPELIAQHPAAERRGSRLLHVCGEQLVDRRFADLPTLLKAGDLLVFNDTRVIKARFFGQKDTGGQVEIMLERIVDATHAICQVRASKAPKAGSTMRLADAFTVKMTGRAGADGDFFALELAEPGDFWELSERYGKLPLPPYIEHPAEGTDETRYQTVYAREPGAVAAPTAGLHFDEDMLATLQAQGINTAFLTLHVGAGTYRPMRVEKIADHRMHSERFEIPPATADAITTTRAAGGQVIAVGTTSLRALESAGNEDGTVQVGGAETSIFITPGYRFQVVDRLITNFHLPKSTLLMLVSAFAGYDHIRAAYAHAVAERYRFFSYGDAMLLERTGQPSDAI
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB_ALCFA
Sequence: MSDTTKPPMARKMGLTAERVHGERRVEDPSRSVMTPPKEELRANVKDLSFWYGEFQALHAVNLPIARNKVTALIGASGCGKSTLLRCFNRMHDLYPGNRYGGEIDLQPEGQNIIAPGIDPILIRLRIGMVFQKPNPFPKTIYENVASGLRIRGIRSRAVLDERVEVSLRQAALWDEVKDRLHQSAYGLSGGQQQRLCIARTLAPNPEIILFDEPTSALDPIATAKIEDLFTDLRDDYTIVIVTHNMQQAARISDYLAFMHLGKMIEFGPTDECFVKPKHAMTEEYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LIPB_GEOSM
Sequence: MICKDVGVIGYAEALRIQEQLVAKVQQGGEEALLLLEHLPVYTIGAGGSRDNVLDPELEPVRVNRGGDVTYHGPGQLVCYPILDLSRRGRDLHRYLRFLERFLVELCAGLGVACHTVPGRTGVWTGNGKLASIGVGVRRWVSMHGFALNVSPDTAPFSRINPCGMPDCRITSLSLELGEELFVDDLKETVAIRFQPFLHLHLPR
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR35_MOUSE
Sequence: MFFYLSKKIAVPNNVKLKCISWNKDQGFIACGGEDGLLKVLRLETQTDDSKLRGLAAPSNLSMNQNLEGHSGAVQVVTWNEQYQKLTTSDQNGLIIVWMLYKGSWYEEMINNRNKSVVRSMSWNADGQKICIVYEDGAVIVGSVDGNRIWGKDLKGIQLCHVTWSADSKILLFGMANGEIHIYDNQGNFIMKMKLNCLVNVTGAISIAGIHWYHGTEGYVEPDCPCLAICFDNGRCQIMRHENDQNPVLIDTGMYVVGIQWNHIGSVLAVAGSQKVVTQDKDINIVQFYTPFGEHLGTLKVPGKQMCSLSWEGGGLKIALAVDSFIYFANIRPDYKWGYCSNTVVYAYTRPDRPEYCVVFWDTKNSEKYVKYVKSLISITTCGDFCILATKADENHPQEENEMETFGATFVLVLCNSIGTPLDPKYIDLVPLFVAMTKTHVIAASKEAFYTWQYRVAKKLTALEINQITRSRKEGRERIYHVDDVPSGSVDGVFDYSKAIQGTRDPICAITASDKTLIVGRESGVIQRYSFPNVALIQKYSLDCRACQLSLNCNSSRLAIIDIAGVLTFFDLDTRVTDSTGQQVVGELLKLERKDVWDMKWAKDNPDLFAMMEKTRMYVFRNLDPEEPIQTSGYICNFEDLEIKSVLLDEILKDPEHPSKDYIMNFEIRSLRDSRALIEKVGIEDASQFIEDNPHPRLWRLLAEAALQKLDLYTAQQAFVRCKDYQGIKFVKLLGNLQSESMKQAEVIAYFGRFEDAERMYQDMDRRDLAIGLRMKLGDWFRVLQLLKTGSGDADDSLLEQANNAIGEYFADRQKWQNAVQYYVKGRNQERLAECYYMLEDYEGLETLANSLPENHKLLPEIAQMFVRVGMCEQAVSAFLKCNQPKAAVDTCVHLNQWNKAVELAKSHSMKEIGSLLARYASHLLEKNKTLDAIELYRKASYFFDAAKLMYKIADEEAKKRTKPLRVKKLYVLSALLIEQYHEQMKNAQRGKVKGKNSEATSALAGLLEEEVLSTTSRFTDNAWRGAEAYHFFILAQRQLYEGYVDTALKTALHLRDYEDIIPSVEIYSLLALCACASRAFGTCSKAFIKLESLETLSAEQKQQYEDLALEIFTKHTPKDNRKSELNSLLEGGEGKLPTCIATGSPIIEYQFWVCKVCKHYVLAQEISNYNFCPLCHSSVE
What is the function of this protein?
As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking (PubMed:21473986).  May promote CASP3 activation and TNF-stimulated apoptosis (By similarity).
What are the official names of this protein?
WD repeat-containing protein 35.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=Immunofluorescence studies in IMCD3 cells show that Wdr35 accumulates at and around centrosomes and basal bodies of serum-starved cells, with fainter punctate staining along the cilia axoneme.
Protein: DCUP_CHRSD
Sequence: MPLQNDRLLRALARQPVDRTPVWMMRQAGRYLPEYRETRGQAGSFMDLCRNAELACEVTMQPLRRYALDAAILFSDILTIPDAMDLGLYFETGEGPKFRKTVRSAEAVDALPVPDAERDLDYVMNAVRTIRHELADSVPLIGFSGSPWTLATYMIEGGSSKDFRHAKALMYGDPAAMHALLDKLARSVTDYLNAQIRAGAQIVQIFDTWGGVLSTPAYREFSLAYMARIVEGLIREHEGRHVPVILFTKQGGQWLETIADSGADAVGLDWTTELSDARARVGDRVALQGNLDPNVLFASPQAIRDEVARILASYGSGPGHVFNLGHGVSQFTDPDHVAAFIEALHELSPRYHG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_SYNFM
Sequence: MLAPKRVKFRKQQKGRMRGTAFRGSTLSFGDFGLKALECGYITSRQIEAARIAITRHVKRGGKVWIRFFPDKPFTKKPAETRMGKGKGSPEGWHAVIKPGRVLYEIKGVPETIAREALNLAAHKLPIPTRFVSRQDVL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: AROC_HELPY
Sequence: MNTLGRFLRLTTFGESHGDVIGGVLDGMPSGIKIDYALLENEMKRRQGGRNVFITPRKEDDKVEITSGVFEDFSTGTPIGFLIHNQRARSKDYDNIKNLFRPSHADFTYFHKYGIRDFRGGGRSSARESAIRVAAGAFAKMLLREIGIVCESGIIEIGGIKAKNYDFNHALKSEIFALDEEQEEAQKTAIQNAIKNHDSIGGVALIRARSIKTNQKLPIGLGQGLYAKLDAKIAEAMMGLNGVKAVEIGKGVESSLLKGSEYNDLMDQKGFLSNRSGGVLGGMSNGEEIIVRVHFKPTPSIFQPQRTIDINGNECECLLKGRHDPCIAIRGSVVCESLLALVLADMVLLNLTSKIEYLKTIYNEN
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: E2F8_HUMAN
Sequence: MENEKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPTANLKMLISAVSPEIRNRDQKRGLFDNRSGLPEAKDCIHEHLSGDEFEKSQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPNGHPDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLEVRRSSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINSAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELTAPSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPSGYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELTAVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYDSPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEVSTEDVH
What is the function of this protein?
Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells.  Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'.  Directly represses transcription of classical E2F transcription factors such as E2F1: component of a feedback loop in S phase by repressing the expression of E2F1, thereby preventing p53/TP53-dependent apoptosis.  Plays a key role in polyploidization of cells in placenta and liver by regulating the endocycle, probably by repressing genes promoting cytokinesis and antagonizing action of classical E2F proteins (E2F1, E2F2 and/or E2F3).  Required for placental development by promoting polyploidization of trophoblast giant cells.  Acts as a promoter of sprouting angiogenesis, possibly by acting as a transcription activator: associates with HIF1A, recognizes and binds the VEGFA promoter, which is different from canonical E2 recognition site, and activates expression of the VEGFA gene.
What are the official names of this protein?
Transcription factor E2F8, E2F-8.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
Protein: YK67_SCHPO
Sequence: MGTFGIVALSIICSIAFLFVAYGVLRLINSIRRRNMMTADVSSVKSSQTWNFLKNPFSNSAKFEALDADDMWDTRVEEAELNTIPSASPFIDHTSETVPFVNTEAPPPRLSSSFSRQSGENAETQSQVSASPFNDKNSPYVQE
What are the official names of this protein?
Uncharacterized protein C607.07c.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein.