PharMolix/UniProtQA huggingface dataset:
Protein: QUEA_RICRS
Sequence: MKLSDFDFDLPSELIAQYPSSERDNSDLLIAVTPPIKTKFYNIIDYLKEGDLLVFNNSKVIKAQLNLGKNITINLNQKLSDDSWSAFAKPARKLHVNDEFYFDNHKVIITEKLAMGEIKVKFKLNDISVFEFLNKYGEMPLPVYIRRSHSLCHPVATTTGSKTYLNNDWIPWSNHGMTNTQNDNDRYQTVYSQIEGSVAAPTAGLHFTKDILDKLKAEGIQATFLTLHVGAGTFLPVKTENIHEHKMHTEYCSITPDTAEIINKAKQEGKRIIAVGTTTLRTLESSCNNGIVKAGSFKTDIFITPGFKFQTADMLLTNFHFPKSTLFMLICAFAGFKEMHELYKYAIKEAMRFFSYGDATLLCRK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_CAUSK
Sequence: MEKVPMTAGGYQTLDEELKRLKTIERPAVIAAISEARQHGDLSENAEYHAAKERQGWIEGRIAEIEDKIARAQVIDVSKLSGKQVKFGATVSVVDEDTEEESRYQIVGDHEADVKEGRISLSSPLSRAMIGKEVGEVVEVYTPGGVKAYEILKVEWV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: GCVHL_STAAM
Sequence: MKKLANYLWVEKVGDLYVFSMTPELQDDIGTVGYVEFVSPDEVKVDDEIVSIEASKTVIDVQTPLSGTIIERNTKAEEEPTILNSEKPEENWLFKLDDVDKEAFLALPEA
What is the function of this protein?
May act as a carrier protein for the ROS scavenging lipoyl moiety and/or as a substrate for oxidoreductases such as SAV0322 and SAV0323.
What are the official names of this protein?
Glycine cleavage system H-like protein, GcvH-L.
Protein: ISPD_SYNC1
Sequence: MSVYVLIPAAGMGRRMGASVNKQYLPLGDRPVLSHTIALFDRHPGIDHIFVICPEAEFPLCRREVIDPYDFRKVRGLVAGGAERQDSVRNGLQACQAAEGDIVLIHDGARPLLPPALIEPTVAAAQQCGAAIVGVPVKDTIKLVTDGMIDSTPDRSLLWQAQTPQAFRFGLIRDAHAQALQQHHKGTDDASLIEWLGGRVAMIEGSYRNIKITTPEDLVLAQAFLDTPGDFQA
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: CYB_BALOM
Sequence: MTNIRKTHPLMKVVNNAFVDLPTPSNISSWWNFGSLLGLCLITQILTGLFLAMHYTPDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLYAHMGRGLYYGSHVFRETWNIGIILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIILALTMVHLIFLHETGSNNPTGILSDMDKIPFHPYYTIKDILGALLLILALLTLTLFAPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILALVPMLHTSKQRSMMFRPFSQFLFWVLVADLLTLTWIGGQPVEHPYVIVGQLASILYFLLILVLMPLASLIENKLTKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SC6A3_MOUSE
Sequence: MSKSKCSVGPMSSVVAPAKEPNAVGPREVELILVKEQNGVQLTNSTLINPPQTPVEVQERETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPVLKGVGFTVILISFYVGFFYNVIIAWALHYFFSSFTMDLPWIHCNNTWNSPNCSDAHSSNSSDGLGLNDTFGTTPAAEYFERGVLHLHQSRGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAMDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSINSLTSFSSGFVVFSFLGYMAQKHNVPIRDVATDGPGLIFIIYPEAIATLPLSSAWAAVFFLMLLTLGIDSAMGGMESVITGLVDEFQLLHRHRELFTLGIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVQQFSDDIKQMTGQRPNLYWRLCWKLVSPCFLLYVVVVSIVTFRPPHYGAYIFPDWANALGWIIATSSMAMVPIYATYKFCSLPGSFREKLAYAITPEKDRQLVDRGEVRQFTLRHWLLV
What is the function of this protein?
Mediates sodium- and chloride-dependent transport of dopamine (PubMed:10375632, PubMed:12606774).  Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity).  Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling (PubMed:30936473).
What are the official names of this protein?
Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, neuron projection. Cell projection, axon. Note=Localizes to neurite tips in neuronal cells (By similarity). Colocalizes with SEPTIN4 at axon terminals, especially at the varicosities (PubMed:17296554).
Protein: DNAA_BORAP
Sequence: MEKSKNIWSLILTEIKKELSEEEFYVWFENLCFLESVGDNIKISTPNLFHKNQIEKRFTKKIKEILTNNGYDNVTIVFTNQSPKTYSSKEESEKTTFNETFPTLDKLKGTTLSKEPLQSIKDRIKMYIKKEEEPKNFKNPFLKKRYTFENFIIGPNNKLAYNASLSISKNPGTKYNPCLIYGGVGLGKTHLLQSIGNKTEELHNNLKILYVTAENFLNEFVESIKTHETKKFKKKYRYLDMLLIDDIHDLQKKEGIQEELFHTFNALYEDNKQLVFTCDRPPSELTNFTDRLKSRFTRGLNVDISKPNFELRVAIIEKKAEEDGIKVPKNILNLVAQKVTTNVRDLEAAVTKLKAYIDLDNIEIDIDIVEKIIKEIIIYEKETTNEPSNKINIENIKKILLRELKIAHKDIEGHSKKPEITKARHIYAYLLRNFTELSTIEIGKIIGGKTHSTVLYSINKIDRDRNKDKEINNLITELMNKIKKN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_LACLM
Sequence: MEFKYNGKVESIELNKYSKTLTQDPTQPATQAMYYGIGFKDEDFKKAQVGIVSMDWDGNPCNMHLGTLGSKIKNSVNQTDGLIGLQFHTIGVSDGIANGKLGMRYSLVSREVIADSIETNAGAEYYDAIVAVPGCDKNMPGSIIGMARLNRPSIMVYGGTIEHGEYKGEKLNIVSAFEALGQKITGNISDEDYHGVICNAIPGQGACGGMYTANTLAAAIETLGMSLPYSSSNPAVSQEKEDECDEIGLAIKNLLEKDIKPSDIMTKEAFENAITIVMVLGGSTNAVLHIIAMANAIGVEITQDDFQRISDVTPVLGDFKPSGKYMVEDLHKIGGVPAVLKYLLKEGKLHGDCLTVTGKTLAENVKTALDLDFESQDIMRPLENPIKATGHLQILYGNLAEGGSVAKISGKEGEFFKGTARVFDGEQHFIDGIESGRLHAGDVAVIRNIGPVGGPGMPEMLKPTSALIGAGLGKSCALITDGRFSGGTHGFVVGHIVPEAVEGGLIGLVEDDDIIEIDAVNNSISLKVADDEIARRRANYQKPAPKATRGVLAKFAKLTRPASEGCVTDL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RFRNP_METTH
Sequence: MLAKQRFVLDTTAFTDNQLRELLGDGDLNLSVDRMLDLIARSRIKLNISCHMPPITYKEFTDYMTRYDCPEETLIKAETWIVKKTPNRYDTQIPSQIFYEYVHDIRERMNKGLRISETLLWEAGIQSIIMASRDVKKTEIESEVLGKAIKDLRKKYRSALRKGTLDSAPDLDVLLLAKELGAGVVAADDGIRVWAERLGLRFLNATSFPKMLKEYLKYYE
What is the function of this protein?
RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.
What are the official names of this protein?
RNA-free ribonuclease P, RNA-free RNase P, Protein-only RNase P.
What is the protein family that this protein belongs to?
Belongs to the HARP family.
Protein: ELMO3_HUMAN
Sequence: MAPPRNVVKIAIKMRDAIPQLIQLDQAKPLAAVLKEVCDAWSLTHSERYALQFADGHRRYITENNRAEIKNGSILCLSTAPDLEAEQLLGGLQSNSPEGRREALRRLVPLASDMIFAREVISRNGLQILGTIIEDGDDLGEVLALSLRAFSELMEHGVVSWETLSIPFVRKVVCYVNMNLMDASVPPLALGLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNQQLQTKAMALLTALLQGASPVERKHMLDYLWQRNLRQFIYKNIIHSAAPMGDEMAHHLYVLQALMLGLLEPRMRTPLDPYSQEQREQLQVLRQAAFEVEGESSGAGLSADRRRSLCAREFRKLGFSNSNPAQDLERVPPGLLALDNMLYFSRNAPSAYSRFVLENSSREDKHECPFARGSIQLTVLLCELLRVGEPCSETAQDFSPMFFGQDQSFHELFCVGIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGTLFRKISSRRRQDKLWFCCLSPNHKLLQYGDMEEGASPPTLESLPEQLPVADMRALLTGKDCPHVREKGSGKQNKDLYELAFSISYDRGEEEAYLNFIAPSKREFYLWTDGLSALLGSPMGSEQTRLDLEQLLTMETKLRLLELENVPIPERPPPVPPPPTNFNFCYDCSIAEP
What is the function of this protein?
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility.  Acts in association with DOCK1 and CRK.  Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases.  May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).
What are the official names of this protein?
Engulfment and cell motility protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_STRT2
Sequence: MDKKTQALVEQYARSLVEVAFEQDAVSTIQEEVRQILTVFAETNLKTFLSQVNVTSEAKKESLSFFQESCSVYMNNFLEVISLNDRANILYDVLKLVLELFDQEDNTYDVTVTSASPLSEEQKTRLLTIVSQKFEIKTRRLVEKIDEELIGGFVIKAKNKFVDTSIRSQLQAFKMNLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL18_RICAE
Sequence: MRSAKLKFEKRRSRIRHKISKTSNRVRLSIFKSGRHIYAQIIDDSKSITIAAASTLDEKIKKLKKSHCNIENAIKVGEEIAKKADSAGIKDVVFDRGGYKYHGVVKALADAAREKIKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: TNR1A_HUMAN
Sequence: MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTTVLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPNPSFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGADPILATALASDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEALCGPAALPPAPSLLR
What is the function of this protein?
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha.  The adapter molecule FADD recruits caspase-8 to the activated receptor.  The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.  Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55, p60.
Protein: NHAA2_PSESM
Sequence: MTQVPNRETPRGVAILTRFLASESAGGIVLMAAALAALIVANSPLSAGYFSTLHSVWLGLSVELWINDGLMAIFFLMVGLEIKREVLAGGLATWGQRALPGFAALGGMLVPALIYIAINWGNPQTLSGWAIPAATDIAFALGVLSLLGNRVPTSLKVFLAALAILDDLGAVTIIAFFYSSGLNLPMLAAAFVTLAVLVALNRLNIRRLLPYLLLGALLWFFVLQSGVHATLAGVALALCIPMGKPEEEARSPLLLLEEKMHYWVAFAVVPIFGFANAGVSLSGITLANLIDPVPLGVALGLFVGKQIGVFLAAVLAIRAGLAVLPEGSNWVQLYGVAILCGIGFTMSLFIGNLAFPGSQHLIDEVKVGVLIGSGLAAVAGIVLLRSRFSRH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CT52_CONLT
Sequence: MLCLPVFIILLLLASPAAPKSLETRIQNDLIRAGLTDADLKTEKGFLSGLLNVAGSVCCKVDTSCCSN
What are the official names of this protein?
Conotoxin Lt5.2, Lt5b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GPDA_RHIEC
Sequence: MSEKIAVIGSGAFGTALAAVIALAGRSAVTLVGRNPSLMADLKSERLHDAVLPGIVLPESLEFSAEAEAVAGASIVLFAMPSQAQADAVRQYGLYLSKDAVVVTCAKGIERTTGNLLTDMLERELPDHPVAVLSGPGFAADIAKGLPTAMAIAADGMETAERLAQAISGRTFRLYASTDRIGVQLGGALKNVLAIACGIVEGRGIGESARAALIARGLAEMSRFVVAKGGQADTVRGLSGLGDLVLTATSHQSRNLRFGIALGRGEKTDPAHGALVEGAFAASVASRLAAELSISMPITDAVSAIIDGRLDISDAIEQLMTRPITTE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEOB_ECOL6
Sequence: MKKLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALKLAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQHPTYSLVCILAVILFNIVVIGLLRRARSRVDVELLATRKSVSSCCAASTTGDCH
What is the function of this protein?
Probable transporter of a GTP-driven Fe(2+) uptake system.
What are the official names of this protein?
Fe(2+) transporter FeoB, Ferrous iron transport protein B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PCBE_PROMA
Sequence: MQTYGNPDPTYGWWVGNSVVTNKSSRFIGSHVAHTGLIAFTAGANTLWELARFNPDIPMGHQGMVSIPHLASLGIGFDQAGAWTGQDVAFVGIFHLICSFVYALAGLLHSVIFSEDTQNSSGLFADGRPEHRQAARFKLEWDNPDNQTFILGHHLVFFGVANIWFVEWARVHGIYDPAIEAIRQVNYNLDLTQIWNHQFDFIQIDSLEDVMGGHAFLAFFQIGGGAFHIATKQIGTYTNFKGAGLLSAEAVLSWSLAGIGWMAIIAAFWCATNTTVYPEAWYGETLQLKFGISPYWIDTGNMDGVVTGHTSRAWLSNVHYYLGFFFIQGHLWHAIRAMGFDFRKVTSAVANLDNSRITLSD
What is the function of this protein?
The antenna complex functions as a light receptor, it captures and delivers excitation energy to photosystems II and I.  The Prochlorales pcb genes are not related to higher plant LHCs.
What are the official names of this protein?
Divinyl chlorophyll a/b light-harvesting protein PcbE.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. IsiA/Pcb subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MTA_CHIRA
Sequence: MDPCECSKSGTCNCGGSCTCTNCSCKSCKKSCCPCCPSGCTKCASGCVCKGKTCDTSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein A, MT-A.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: RHAM_ECO57
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKARNLLFATVEIESEERWNAVASTEICQRWWKYMTDVMPANPDNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_STRT1
Sequence: MEKFTIYTGTTVPLMNDNIDTDQILPKQFLKLIDKKGFGKYLMYSWRYKDNKYTEDPDFVFNRPEYRKATILITGDNFGAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQPIEVRRKLEQLKPTDEVTVDLEQQKIISPVGEFTFEIDGEWKHKLLNGLDDIGITMQYEDLITEYEKHRPSYWQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: NCPP_ECO55
Sequence: MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQPFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSATLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVILALSPFHNAVY
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: PLIAA_BOTMO
Sequence: MRLILLSSLLLLGIFLANGHEEDPDGKVLNSLIDTLMHLQKLYANLKYSFLTVHRARSFGSGSERLYVTNKEIKNFEALRQICEQAEGHIPSPQLENQNKAFANVLERHGKEAYLVVGDSANFTNWAAGEPNKAAGTCVKADTHGSWHSASCDDNLLVVCEFYFIL
What is the function of this protein?
This phospholipase A2 inhibitor binds directly phospholipase A2 in the presence or absence of calcium.
What are the official names of this protein?
Phospholipase A2 inhibitor clone 10, alpha-PLI.
What is the protein family that this protein belongs to?
Belongs to the alpha-type phospholipase A2 inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in plasma.
Protein: DHC4_ALTCI
Sequence: MSSPRAAPSHDTFPNAKRRKVRKGTHSCWECKRRKMKCIFDPRITSTSCNGCRQRGSPCISQEFVQDDSHVAHGANDSASLDASTPIATPSDDARRADHDILTPVSVDSEPYRYLPSSKSSDKRFTTRSSNDASTCPMKHEKLSKYLHEALPSREDTERICKASRHSSILAHELLTVPYDTLYRNGLKTPDSLLAIPEPHVHPVLIAKHMLQLATFLQHLHPDLDKEIKVLSESPRAIMQRLVDIAIHHITTNNELLGSVESLECVMIESLYQANIGNLRKSWVAGRRAMSIAQLMGLHRSDSLSQYKVLDPKTEYNPQLMWLRIVTLDRHLCLLLGLPQGCTDRSMASETCLSNDTQMGRLERLHCVLMSRILERNEYSTNAQHAVVTREIDLELQKAARGLTSKWWLAPKLNTASADLQVHFWDTRRLLAQIFHYNLLIQLHLPYMLRVSSDESKHDYSRMTCVNASREVLSRYITLRNLNRIAYSCRTVDFIALMAAMALLLAHMNCHRAGAVNPLAHQYLSDRAMIEQVQENMHEINKLNSDALSAQSADLLKKLLAIEMEAGDTRVSVSEASNGVVQQDGTTREEDGVVSVQVPYFGIIRIGKDTPTKNQASVTATMHGTAPLHLDRFPTSINTNSDPVHVHSQADFPSSTQLSSSSHPNTPSPALSLNNIPFHATCMAALPDSSVVFTRQQHQKQQQEHQEFGGDLATVSDTSFPSSLHATWQDNFPELAAGSEDWAFQGVDMAFFESIMRSDTNLGQ
What is the function of this protein?
Transcription factor involved in regulation of the dehydrocurvularin biosynthesis gene cluster (PubMed:26493380).
What are the official names of this protein?
Dehydrocurvularin biosynthesis regulator, Dehydrocurvularin biosynthesis protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: NEUM_PANTR
Sequence: MLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA
What is the function of this protein?
This protein is associated with nerve growth.  It is a major component of the motile 'growth cones' that form the tips of elongating axons.  Plays a role in axonal and dendritic filopodia induction (By similarity).
What are the official names of this protein?
Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43.
What is the protein family that this protein belongs to?
Belongs to the neuromodulin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Synapse. Cell projection, filopodium membrane; Peripheral membrane protein. Perikaryon. Cell projection, dendrite. Cell projection, axon. Cytoplasm. Note=Cytoplasmic surface of growth cone and synaptic plasma membranes.
Protein: CAZA2_BOVIN
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRISFKFDHLRKEATDPRPYEAENAIESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: POMT2_DROPS
Sequence: MAASVVKTPKCPRRGSAKEQQSKASPKSNNESNNWHWWILLASVFLITFATRFYKVTEPDHICWDETHFGKMGSWYINRTFFFDVHPPLGKMLIGLSGYLTGYNGTFPFEKPGDKYNETAYQGMRYFCTTLGALIMPMGFDTVYDLTRSHEAALLSAAYLIFDVGLLTLNQYILLDPILLFFMMGSVWGMVKISKATASGGSYSVRWWFWLFLTGTMLSCTISVKFVGLFVVLLVGLHTATELWLILGDLGQPIVETLKQIACRAIALILWPILLYTLFFYIHLSVLNRSGNGDGFYSSAFQSRLIGNSLYNASMPRDVAYGSVVTIKNHKTGGGYLHSHFHLYPKGSGARQQQITTYTHKDDNNKWVIKPHNKQRLPKDKLQLLRHGDLVRLEHLVTKRNLHSHSEPAPMTKKHLQVTGYGESGVGDANDVWRVLIVGGKVNETVHTVTSRLMLIHYLQNCALTSSGKQLPKWGFEQQEVSCNLNVRDKYAHWNVEDNEHKLLPSVSFSVYAPGFFARFLESHAVMLQGNAGLKPKEGEVTSRPWQWPINYRGQFFSGSSYRIYLLGNPVIWWSNLVFLALFVAVFLGNAILEQRRAGQARALVRSQADSEDSEPSTTDVPLCTCCPEEQQLLSRPREEHRDPLGAAAWLFVGWLLHYLPFWAMGRVLYFHHYFPALIFNSLLTGVMFHHIIQSLPRWIQHVLLGGLLSLIVYSFALFSPLAYGMSGPLANEPNSTMHSLKWLSTWEF
What is the function of this protein?
Rt/POMT1 and tw/POMT2 function as a protein O-mannosyltransferase in association with each other to generate and maintain normal muscle development.
What are the official names of this protein?
Protein O-mannosyl-transferase 2, Dolichyl-phosphate-mannose--protein mannosyltransferase 2, Protein twisted.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.