PharMolix/UniProtQA huggingface dataset:
Protein: SUCC_COXB1
Sequence: MNLHEYQSKHLLKKYNIPVPASEVVFNPDAAVDAAAKIGGDRWVVKAQVHAGGRGKAGGVRLVKNKEELKSAVKALLGTRLVTYQTDERGQPVNQILVEQTSDIARELYLGAVIDRASQRIVFMASTEGGVEIEKVAEKSPEKILKVTVDPAIGLQPFQCRQLFFGLGLQDLKQMRSFTDIVMGLYRLFTERDLSLLEINPLVITGSGELICLDAKINIDDSALYRQSELREMRDTTQEDEHETMAQQWELNYIKLDGNIGCMVNGAGLAMATMDLIKLSGGDPANFLDVGGSATKERVTEAFKIIASDKNVKGILVNIFGGIVRCDLIADGIISAVKEVGIDVPVVVRLEGNNAQLGAKKLADSGMNIIAAKGFADAAEQIVKQVGVIA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: ATF1A_DANRE
Sequence: MARLLLRRGFFSSHIRMSSDQLGELGTGAGKGGGGGGSVRAAGGSFGRREAAEEERYFRQKEREQLAALKNHHEEEIDHHKKEIERLQREIDRHKGKIRKLKHDD
What is the function of this protein?
Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix.  Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase (By similarity).  Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme (PubMed:23135403).
What are the official names of this protein?
ATPase inhibitor A, mitochondrial, ATP synthase F1 subunit epsilon A, Inhibitor of F(1)F(o)-ATPase A, IF(1) A, IF1 A, Protein pinotage.
What is the protein family that this protein belongs to?
Belongs to the ATPase inhibitor family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FCG3A_RAT
Sequence: MWYLLLPTALLLTVSSGVGAGLQKAVVNLDPEWVRVLEEDCVILRCQGTFSPEDNSTKWFHNKSLISHQDANYVIQSARVKDSGMYRCQTAFSALSDPVQLDVHADWLLLQTTKRLFQEGDPIRLRCHSWRNTPVFKVTYLQNGKGKKYFHRNSELSISKATHADSGSYFCRGIIGRNNISSASLQISIGDPTSPSSFLPWHQITFCLLIGLLFAIDTVLYFSVQRSLQSSVAVYEEPKLHWSKEPQDK
What is the function of this protein?
Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG).  Binds with intermediate affinity to both IgG2a and IgG2b.  Can bind to IgG2a and IgG2b monomers.  Does not display binding to IgG1 or IgG3 (By similarity).  Recognizes neutralizing virus-specific IgGs displayed on the cell surface of infected cells and triggers antibody-dependent cellular cytotoxicity (ADCC).  Confers protection to lethal influenza virus infection (By similarity).  On splenic dendritic cells, uptakes antigen immune complexes and efficiently divert them into MHC class I and II antigen presentation pathways to provide for superior priming of CD4-positive and CD8-positive T cell immune responses (By similarity).  Mediates neutrophil activation by IgG complexes redundantly with FCGR2A (By similarity).  Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (By similarity).  Also acts as a receptor for the Fc region of immunoglobulin epsilon (IgE).  Binds with low affinity to both the a and b allotypes of IgE.  Has also been shown to bind to IgE allotype a only but not to allotype b.  Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes.  Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of pro-inflammatory cytokines and the late phase of cutaneous allergic reactions (By similarity).  Mediates enhanced ADCC in response to afucosylated IgGs (PubMed:34485821).
What are the official names of this protein?
Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, CD16-2, FcgammaRIV.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS18_LIGS1
Sequence: MAQQRRGGRRRRKVDYIAANHIEYIDYKDTDLLRRFISERGKILPRRVTGTSAKNQRKLTVAIKRARIMGLLPFVAED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RNAS2_PONPY
Sequence: MVPKLFTSQISLLLLLGLLAVDGSLHVKPPQFTWAQWFETQHINMTSQQCNNAMQVINNFQRRCKNQNTFLRTTFANVVNVCGNPNITCPSNRSRNNCHHSGVQVPLIHCNLTTPSPQNISNCRYAQTPANMFYIVACDNRDPRRDPPQYPVVPVHLDRII
What is the function of this protein?
This is a non-secretory ribonuclease.  It is a pyrimidine specific nuclease with a slight preference for U.  Cytotoxin and helminthotoxin.  Possesses a wide variety of biological activities.
What are the official names of this protein?
Non-secretory ribonuclease, Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, RNase 2, Ribonuclease US.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Lysosome. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Protein: SHO1_LODEL
Sequence: MGFKIRNFTGDPFAIATVSFGLIAWIVALAGAAASSQGSFPHFTWWGIAYQIVIILVITVLYLNNNIELYKFTLVGLVSIGFIYTTNSTNNLVYNSSSSGNLCCAAGCILLSILNLIWILYFGGHPESPTNQFIDSFSSNKYANEYIGRSSVLKTEPFDDQQGFNSAASKRFTSTGISLPQENVSQMSQTNTHSQQQQHSTNAANASNATSYFPLTQLHGLENSSQDMMGSAPRDLTQNTNTNSSGTKRNTLYTDSEGGTGITFRYKAKALYSYDANPDDINEISFIKDEILDVDDVDGKWWQARRANGQVGICPSNYVKLIDT
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KCY_STRZP
Sequence: MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYMALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAIAAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKENIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAEAEKRM
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_BACFR
Sequence: MLSLQFITHQTENYSYLESARMALEGGCKWIQLRMKEASPEEVEAVALQLKPLCKAKEAILILDDHVELAKKLEVDGVHLGKKDMPIGEARQMLGEAFIIGGTANTFEDVKLHHAAGADYLGIGPFRFTTTKINLSPVLGLEGYTSILAQMNEADIRIPVVAIGGIVAEDIPAIMETGVNGIALSGAILQAPDPVEETKRILNI
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: SYH_BLOFL
Sequence: MIKYRNSSIHIQSVRGMHDCLPKDVIQWQYIEDVLKTILNGYGYNEIRFPIIECTDLFKRSIGEVTDVVEKEMYTFIDQHGNDLTLRPEGTSGCVRAGIENSLFYHQEPRLWYMGPMFRRERPQKGRYRQFHQFSAEAFGCVGPDIDVELILITNRCWKELGISNYLTLELNSIGLLSSRMIYRKKLISFLEKNKHNLDDSSKRRLYSNPMRILDTKNVKIKELLAHAPVLSDYLDDCSKNHFLNLCRLLDIANVTYIVNPYLVRGLDYYNRTVFEWVTDKLGVKKTICAGGRYDDLIKQLGGGSIPAVGFAIGLERVVLLMKLIKSSIINTRNVYIDVYLIRLGTYYQEYSIKLSEHIREKLPFLRLMVDCGGGNFKQQIDRAEKNNSRFVIVVDDKNFFEQTIILKELQSKKQEILKYDEIILKLRKIYNM
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_RHILO
Sequence: MSALKTHIAKVAAGTALSFEEAREAFDIIMSGDATPGQIGGFLMALRVRGETVSEISGAVATMRAKMLRVEAPAGAIDIVGTGGDNSHSVNISTGSAFVIAAAGVPVAKHGNRGLSSLTGAADVLIALGVKIDIPPDAIGRCIHEAGVGFMFAPAHHPAMKHVGPTRVELGTRTIFNLLGPLSNPAGVVRQMVGVFLPEWILPVAETLKALGTEHAWVVHGDGYDEITTTGETQVAELIGGEIRSFTLTPEEVGLKRHTKDELRGGDAAYNANALRDMLDGAAGAYRDTVLMNAGAGLVIAGKATTLGDGIALAAQAIDSGRALQVLDRLVEISNG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: FLII_CAEEL
Sequence: MSTGVLQFVKGIDFSGNDFSGDRFPHDVEQMTQMTWLKLNDSKLEQVPDELSRCANLEHLQMAHNQLISVHGELSDLPRLRSVIVRDNNLKTAGIPTDIFRMKDLTIIDLSRNQLREVPTNLEYAKGSIVLNLSYNNIETIPNSVCANLIDLLFLDLSNNKLDMLPPQIRRLSMLQSLKLSNNPLNHFQLKQLPSMTSLSVLHMSNTNRTLDNIPPTLDDMHNLRDVDFSENNLPIVPEALFKLRNLRKLNLSGNKIEKLNMTEGEWENLETLNMSHNQLTVLPDCVVKLTRLTKLYAANNQLTFEGIPSGIGKLIQLTVLHLSYNKLELVPEGISRCVKLQKLKLDHNRLITLPEGIHLLPDLKVLDLHENENLVMPPKPNDARKKLAFYNIDFSLEHQRKIAGQMTSPSSSISSVHSGGARQDALARRKEFIRRRKQQADQQSADKVIQGMSKIAGVGAALTEKQQEEEERQLEAKSAVNWKKNIEKNRRHIDYSDIFDEDVGSDEGMWVWEIENFYPSIMDEAFHGQFYDADAYLVLKTTREASGQLRHAIFYWLGEHASLDKGMCSAVHAVGLRNHLNATCRTQREEMNDETEEFLTLFGEEIVYIEGGRTISGFYTTEKPAHLTRLYRAGVNGTAVEMEPVPLSVESLDPRFCFLLDAGETIWIWSGYKSRITVSNKARLFAERLNKRDRKGKSEIETCRQARCPPEFWQALTGNPDKPQGAIVEHVPEGFVAERKKLYKVNIGMGFLELPQVELPKGIAKQDMLGSKGVFVLDSNSDIFLWIGKKANRLLKMAGQKLVVELHQMIDRPDYAQVYRETEGEESMMFRSKFAGWDEIVPVDYTRTSDSVQRVPDLKVIVKKDNMMRADLAALFLERQPSMSYEESEELMEDCNYDLELMESFVLEGKKFVKLPQKEFGIFYTMDCYVFLCRYAVMPEEDEEGEDEHDEDDKPEMDFKCVVYFWQGRDASNMGWLNFTFQLQPNFEEIFKDKLEVVRMYQQQENHKFLSHFKRKFLIKRGRRGLTKNLGGKWPELFQMRANGSSVCNRTIQVDCQANQLCSAFCHMLRIPFKEIEEDGHRGVVYVWMGKDSDPREHEFARQVASDLVVRDDDNDFRIVEVQEGEENEEFWKVLGGKKKYETDSSFVKHTRLFRCTNEKGYFAISEKTVDFCQDDLDDDDIMILDNGDAVFLWIGARSSDIEAKLSYQAAQVYHASMRMKANEKPRKFMLAVRGRESCRFRKCFHAWSKMKEPMG
What is the function of this protein?
May play a key role in embryonic cellularization by interacting with both the cytoskeleton and other cellular components.
What are the official names of this protein?
Protein flightless-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
Protein: HEMA_INCJH
Sequence: MFFSLLLVLGLTEAEKIKICLQKQVNSSFSLHNGFGGNLYATEEKRMFELVKPKAGASVLNQSTWIGFGDSRTDKSNSAFPRSADVSAKTADKFRFLSGGSLMLSMFGPPGKVDYLYQGCGKHKVFYEGVNWSPHAAINCYRKNWTDIKLNFQKNIYELASQSHCMSLVNALDKTIPLQVTAGTAGNCNNSFLKNPALYTQEVKPSENKCGKENLAFFTLPTQFGTYECKLHLVASCYFIYDSKEVYNKRGCDNYFQVIYDSFGKVVGGLDNRVSPYTGNSGDTPTMQCDMLQLKPGRYSVRSSPRFLLMPERSYCFDMKEKGPVTAVQSIWGKGRESDYAVDQACLSTPGCMLIQKQKPYIGEADDHHGDQEMRELLSGLDYEARCISQSGWVNETSPFTEKYLLPPKFGRCPLAAKEESIPKIPDGLLIPTSGTDTTVTKPKSRIFGIDDLIIGVLFVAIVETGIGGYLLGSRKESGGGVTKESAEKGFEKIGNDIQILKSSINIAIEKLNDRISHDEQAIRDLTLEIENARSEALLGELGIIRALLVGNISIGLQESLWELASEITNRAGDLAVEVSPGCWIIDNNICDQSCQNFIFKFNETAPVPTIPPLDTKIDLQSDPFYWGSSLGLAITATISLAALVISGIAICRTK
What is the function of this protein?
Binds to the N-acetyl-9-O-acetylneuraminic acid residues on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HEF2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.  Displays a receptor-destroying activity which is a neuraminidate-O-acetyl esterase.  This activity cleaves off any receptor on the cell surface, which would otherwise prevent virions release.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.
What are the official names of this protein?
Hemagglutinin-esterase-fusion glycoprotein, HEF.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: RK33_COFAR
Sequence: MAKGKDVRVTVILECTDCVRNSVNKVSTGISRYITQKNRHNTPNRLELKKFCPYCYKHTVHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ASGR2_HUMAN
Sequence: MAKDFQDIQQLSSEENDHPFHQGEGPGTRRLNPRRGNPFLKGPPPAQPLAQRLCSMVCFSLLALSFNILLLVVICVTGSQSEGHGGAQLQAELRSLKEAFSNFSSSTLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLKHFPVDLRFVACQMELLHSNGSQRTCCPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFNTWIGLTDSDGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSEDCVEVQPDGRWNDDFCLQVYRWVCEKRRNATGEVA
What is the function of this protein?
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed.  The receptor recognizes terminal galactose and N-acetylgalactosamine units.  After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated.  The receptor then returns to the cell membrane surface.
What are the official names of this protein?
Asialoglycoprotein receptor 2, ASGP-R 2, ASGPR 2, C-type lectin domain family 4 member H2, Hepatic lectin H2, HL-2.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: LTG19_ARATH
Sequence: MILAILALVIATFLYGGATTVQAGCRDTLTSLSPCLYYLNGGSSSPSWSCCRQFSTVVQSSPECLCSVVNSNESSFYGFKFNRTLALNLPTACNVQTPSPSLCNTGGNVPTTLPANTPVGSPRSAPSPSGTTSPANTPSGSKKFPLSNESSSKSNVIILSFVSIALVLAII
What is the function of this protein?
Probable lipid transfer protein.
What are the official names of this protein?
Non-specific lipid transfer protein GPI-anchored 19, AtLTPG-19, Protein LTP-GPI-ANCHORED 19.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CT452_HUMAN
Sequence: MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI
What are the official names of this protein?
Cancer/testis antigen family 45 member A2, Cancer/testis antigen 45-2, Cancer/testis antigen 45A2.
What is the protein family that this protein belongs to?
Belongs to the CT45 family.
Protein: RPOA_BURP6
Sequence: MQTSLLKPKIIAVESLGENHAKVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTLDGVQEDVVNLLLNLKGVVFKLHNRDEVTVTLRKEGEGVVTAGDIELAHDCEVINPNHVIAHLSKGGKLDVQIKVEKGRGYVPGNVRRYGDETAKIIGRIVLDASFSPVRRVSYTVESARVEQRTDLDKLVMNIETSGVITPEEAIRQSARILVDQLSVFAALEGTETAAEAPSRAPQIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: ARI3C_HUMAN
Sequence: MEALQKQQAARLAQGVGPLAPACPLLPPQPPLPDHRTLQAPEGALGNVGAEEEEDAEEDEEKREEAGAEEEAAEESRPGAQGPSSPSSQPPGLHPHEWTYEEQFKQLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECETRALSSPGELQAAIDSNRREGRRQAYTATPLFGLAGPPPRGAQDPALGPGPAPPATQSSPGPAQGSTSGLPAHACAQLSPSPIKKEESGIPNPCLALPVGLALGPTREKLAPEEPPEKRAVLMGPMDPPRPCMPPSFLPRGKVPLREERLDGPLNLAGSGISSINMALEINGVVYTGVLFARRQPVPASQGPTNPAPPPSTGPPSSILP
What are the official names of this protein?
AT-rich interactive domain-containing protein 3C, ARID domain-containing protein 3C.
What are the subcellular locations of this protein?
Nucleus.
Protein: FMT_SHELP
Sequence: MKPLKILFAGTPDFAARHLQALIDSEHQVIGVYSQPDRPAGRGKKLQASPVKALALEHDIPVYQPVSLRNEDAQAELAALGADIMVVVAYGLILPQVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDAATGVTIMQMDIGLDTGDMLLKTHLPIEDRDTSASLYEKLAEQGPSALIQALKGLAEGSLTPEPQDEALANYAEKLSKEEAQLDWRKPAEQLWREVRAFNPWPASHFPHQDAAIKVWQASVSIEAAKQAPGTIIRADKQGIAVATGEGALVLETIQLPGKKAMAVADVLNARGDWFTPGTQLQGVTPADEAQA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MSRP_ECOSE
Sequence: MKKKQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHADLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPVDKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: T1MH_HAEIN
Sequence: MPASARWQALQEVSILNTGAELPWGGKFSGVAKLIDDAFDAIEKDNEKLKGVLQRISGYAVNEDTLRGLIILFSDTHFTRPTYNGEPVHLGAKDILGHVYEYFLSRFAQAEGKRSGQYFTPKSIVSLIVEMLEPYSGRVYDPAMGSGGFFVQTERFITAHQGNINNVSIYGQEFNPTTWKLAAMNMAIRGIDYDFGKYNADSFTQPQHIDKKMDFIMANPHFNDKEWWNESLADDPRWAYGTPPKGNANFAWLQHMIYHLSPNGKIALLLANGSMSSQTNNEGEIRKAIINADLVECMVALPGQLFTNTKIPACIWFLNRNKKRKGEVLFIDARQIGYMKDRVLRDFTADDIAKIADTLHAWQTSDGYEDQAAFCKSATLEEIKNNDFVLTPGRYVGTAEQEDDGVPFAEKMQNLTALLKEQFAKSAELEAEIKKNLGGLGYE
What is the function of this protein?
The subtype gamma methyltransferase (M) subunit of a type I restriction enzyme.  The M and S subunits together form a methyltransferase (MTase) that methylates adenosines in the sequence 5'-RAACN(5)TAG-3'.  Methylation protects against cleavage by HindI (PubMed:4591672) (Probable).  In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site.  Whether the DNA is cut or modified depends on the methylation state of the target sequence.  When the target site is unmodified, the DNA is cut.  When the target site is hemimethylated, the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated (Probable) (PubMed:12654995).  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage (By similarity).
What are the official names of this protein?
Type I restriction enzyme HindI methylase subunit, M protein, Type I methyltransferase M.HindI, M.HindI, Type I restriction enzyme HindVIIP methylase subunit.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: MINE_XYLFT
Sequence: MGLIDFLRNKTKTAETAKNRLQIIIAQERTQRGGPDYLPLLQRELLEVIKKYVKIDADAVKVDLIKDGANDVLDISVALPDDSER
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity).
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: GVPN_ANCAQ
Sequence: MTSEAASKDPISVLSGFGAGTATSASKNGGRTTPSALTPRPRSGFVETEQVRDLTRRGLGFLNAGYPLHFRGPAGTGKTTLALHVAAQLGRPVIIITGDNELGTADLVGSQRGYHYRKVVDQFIHNVTKLEETANQHWTDHRLTTACREGFTLVYDEFTRSRPETHNVLLGVFEERMLFLPAQAREECYIKVHPEFRAIFTSNPQEYAGVHASQDALADRLATIDVDYPDRAMELAVASARTGMAEASAARIIDLVRAFRASGDYQQTPTMRASLMIARVAALEGLDVSVDDPRFVQLCSDALESRIFSGQRAEAVAREQRRAALYALIETYCPSVAKPRARRAGGGARAGVEGALP
What are the official names of this protein?
Gas vesicle protein GvpN.
What is the protein family that this protein belongs to?
Belongs to the CbbQ/NirQ/NorQ/GpvN family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: DCL1_PHANO
Sequence: MTWAGDVEEQDDYFSCSDVSTSGDRRKRAPQTVTQEEVDQATSKIANEGQLSIRDILASQDTAVRITNPRDYQMELFLRAKMQNTIAVLDTGTGKTHIATLLLRHVLEEELENRAKGCAHKMAFFLVDSVNLVFQQANVLRCGLDQGVEGISGAMGQSLFQKQTWDKLFAVNMVIVCTAQVLVDCMMHSFMSISRMNLLIFDEAHHAKSNHPYARVMKDYYAHELDTSKRPRIFAMTASPVDVKGQSAEHVREAARELETLLHSRIATTSDSALARNSITRPEEEVAVYTRLRNEFETPLHQKVKAKYGDVAPFRKLFITAKLHASELGRWASDMYWSFAFADEQSRKLQIREELKYNRSKRDWSAAELDAQMARLKEATAFVQQYEIGAPTLSEQDLSSKVMKLQYWLNLYYERTTLARCIVFVEKRHTAQLLKLIFDHIGGPNLHCDVLVGINNRAGEENVSLRSQILTLQKFRRGELNCLFATSVAEEGLDIPQCNLVVRFDLYRTMIGYVQSRGRARHRNSKYLHMLEAENKEHTERLMNARHDENIMREFCKDLTHDRQLGDVEQEKAELIALEDKLFPSYTDEKSGAKLTYRSSLSILSHFVATYPSPDHNTMAQPTYVVNPKISDDPRDPQRNGFVCEVILPEHCPIISMVGQVYSRKTIAKCSAAFKMCIELRRKDHLNEFLLPTISKYLPAMRNALLAVSEKKKGNYAMVIKPTFWKQDRDTVPESLHLTIIDADRGLDRPHQPLAMLTRRPFPQLPSFPIYLTDCRPSNIVSQSLHIPISLTPELLEMFTRFTLRIFEDIYNKVYDYDVSKMSYWMLPVIEHRVASVRSMSNPQEVLDMDQIRKVYNEPFWKWSPQSRTDDLIDRYFVDPMNGGRRYYSDRLAPHLKPQDPVPANVPRQNHKFMKNILDFSDSKWMKSRDITRWHQDQPVLQVEKIPFRRNHLANVEDKEKKELANLETYICPEPLHISNLATPFVVMCYVLPAIIHRFESYLIALDACDVLDLKVSPALALEALTKDSDNSEEHGEEKINFKSGMGPNYERLEFLGDCFLKVATSLSVFVQQPEENEFEFHVRRMLMLCNQNLMETAVGKKKLYKYVRTDAFSRRNWYPEGLKLLRGKGLKKTEEDWLNVTHNLGDKSVADVCEAFIGAAFMQHHKGGQWTPNDWDEAVKAVKLFANSDDHLMEKWTDYYAAYTKPKYQTAGATATQLDLAHKIEMKHPYRFRYPRLLRSAFIHPSQPFMWENIPSYQRLEFLGDSLLDMAFIMHLFYKYPDKDPQWLTEHKTPMVSNKFLGAVCVKLGWHTHMKQNTAILSSQIRDYVYEVEEAEREANGAVDYWVSVSEPPKCLADVIEAFVAAIFVDSEFDFNVVQKFFDLHLKPFFLDMTLDAYENFASNHPTTRLSRLLSINFGCSEWRMGALETETLIPGKGKAIAAMVMIHDKVHFHSLGQSGRYARVRASHAALEKLEGLPPYEFRSKYGCDCVDEGEGEAGVDEAAVSKKVELMREAIGPSI
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.