PharMolix/UniProtQA huggingface dataset:
Protein: GPX1_PIG
Sequence: MCAAQRSAAALAAVAPRSVYAFSARPLAGGEPISLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNGEILNCLKYVRPGGGFEPNFMLFEKCEVNGANAHPLFAFLREALPTPSDDATALMTDPKFITWSPVCRNDIAWNFEKFLVGPDGVPLRRYSRRFLTIDIEPDIEALLSQEPSSA
What is the function of this protein?
Protects the hemoglobin in erythrocytes from oxidative breakdown.  In platelets, plays a crucial role of glutathione peroxidase in the arachidonic acid metabolism.
What are the official names of this protein?
Glutathione peroxidase 1, GPx-1, GSHPx-1, Cellular glutathione peroxidase.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_PSEP1
Sequence: MAAKDVKFGDSARKKMLVGVNVLADAVKATLGPKGRNVVLAKSFGAPTITKDGVSVAKEIELKDAFENMGAQLVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKATAAVVAELKNLSKPCADSKAIAQVGTISANSDNSIGEIIAEAMEKVGKEGVITVEEGSGLENELSVVEGMQFDRGYLSPYFVNKPDTMVAELEGPLLLLVDKKISNIRELLPVLEAVAKAGRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAVLTGGQVISEEIGLSLETATLEHLGNAKRVILSKENTTIIDGAGADTEIEARVKQIRAQIEETSSDYDREKLQERLAKLAGGVAVIKVGAGTEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRALAAIVDLKGDNEDQNVGIALLRRAVESPLRQITANAGDEPSVVADKVKQGSGNFGYNAATGEYGDMIEMGILDPAKVTRSALQAAASIGGLMITTEAMVADLPEDKPAAGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_THEM4
Sequence: MKLKTMTMEWTGDELILIDQRKIPLKEEYMSCKTYKEVALAIKEMVVRGAPAIGASAAFGYVLGAREKFVEDFEAFVEKMREVKEVLANTRPTAVNLFWALNRMENALRKYGKVEGVLEFLENEALNIAKEDIEVNMAIGRYGAQLLKDGDTVLTHCNAGALATVDYGTALGVIRAAVEQGKRIKVFADETRPYLQGARLTAWELMKDGIDVTLISDNMSGWAMKLGKINAVIVGADRVASNGDVANKIGTYMVAVLAKRHGIPFYVAAPTSTIDLNTQTGKDIPIEERKHTEVTHCGGTQIAPDNVKVFNPAFDVTNAELITAIITEKGIVYPPYEENLKKLFEE
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: YPHA_ECOLI
Sequence: MNTLRYFDFGAARPVLLLIARIAVVLIFIIFGFPKMMGFDGTVQYMASLGAPMPMLAAIIAVVMEVPAAILIVLGFFTRPLAVLFIFYTLGTAVIGHHYWDMTGDAVGPNMINFWKNVSIAGAFLLLAITGPGAISLDRR
What are the official names of this protein?
Inner membrane protein YphA.
What is the protein family that this protein belongs to?
Belongs to the DoxX family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBL_AJUCH
Sequence: MSPQTETKASVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVLGEKDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAAEGNTIIREACKWSPELAAACEVWKEIKFEFPAMD
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UNG_CHLTB
Sequence: MHEAFTIEQLPPSWQEQLKDEWSQPYWSQLLAFLKSEYAQAKIYPKKENIFAALRSTPFDQVRVVILGQDPYHGEGQAHGLSFSVPRGQALPPSLRNIFQELHTDLGIRNESGCLQAWADQGVLLLNTVLTVRAGEAFSHAGRGWERFTDAIVTKLIQNRTHVIFVLWGNAARQKCNLLFQTKHQHAVLACPHPSPLAAHRGFFGCCHFSKINYLLKKQGKTMINWKIE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_ADICA
Sequence: MIYTGIEYIFVNISFVMFFFVTLLNLINLFYKIDKIDHFSKNSMTIAFFCTTGFLITRYLQTRHLPLGNLYESLMFLSWGFSLLYLILEVRDQIGLSHAVLAPGAMLIHAFATLSLPQQMRSPTLLVPALQSQWLMMHVSAMLISYITLLCGSLLAITLLSLFYGKVGSVTLEHKFEKQSFFFLMNPRKNLWKQTGAENYSYFLISNSRKCQLINCLDKWACQTISLGFSLLTIGILSGAVWANEAWGSYWSWDPKETWALVTWLVYAIYLHTKVDKRKMGEGPAMTASMGFFLVWICFLGVNLLGVGLHNYGWLA
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL28_BURM1
Sequence: MARVCQVTGKAPMSGNNVSHANNKTKRRFLPNLQNRRFWVESENRWVRLRVSNAGLRLIDKNGIDSVLADLRARGEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TLP_ACTCC
Sequence: MSTFKSLSLSALLFIAFLFTCARGATFNIINNCPFTVWAAAVPGGGKRLDRGQNWIINPGAGTKGARVWARTGCNFDGAGRGKCQTGDCNGLLQCQAFGQPPNTLAEYALNQFNNLDFFDISLVDGFNVAMEFSPTSGGCTRGIKCTANINEQCPNELRAPGGCNNPCTVFKTDQYCCNSGNCGPTDYSRFFKTRCPDAYSYPKDDQTSTFTCPGGTNYKVVFCP
What is the function of this protein?
Has antifungal activity against B. cinerea, C. comatus, M. arachidicola, P. piricola, C. albicans and S. carlsbergensis.  Inhibits HIV-1 reverse transcriptase.
What are the official names of this protein?
Thaumatin-like protein.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SERC_XANOR
Sequence: MTRAFNFSAGPATLPESVLRQAQAEMVEWNGVGASIVEISHRSADFMAVAAAAEADLRSLLSIPDDYAVMFTAGGATTIQALLPLNFAAPGQAADYVITGHWGKTAIKQASPYVDARIAADAETGGFLDIPPAASWTLSPHSAYVHITANETIHGVEFRDTPEVGTLPLFADFSSSIASEPLDISRYGLIYAGAQKNLGPVGISVVIVRRDLLERAGQPRADIFNYASHVARDSMLNTPPTWNWYLLGLTVKWMLEQGGVQEFARRNAEKAALVYGAIDGAGGFYRNLITPAVRSRMNIPFFLPDEQLDALFVSESKAAGLLALKGHKAVGGIRASLYNAMPLAGAQALANFMHDFQQRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POM34_YEAST
Sequence: MKIQAGQLGLDDNDVPGPLPDTDSKPSSQSQNDTPMFKLGNFESPVLKELSRRTVNKEMETQRIMTNVIAFAFWNLLVKFIKFFWNNTHVGRQFCNRLSRIHLYMLTFHTLKKANIIYHTTFSWLNAELLDYLFHLLISLNILFSLWKLLSTVKVSDLNLTDRQKKLLGVDMQSSVDTGLQPQHPHYVSTSKISQMAQNKTHIPQTNLKNHPAYLFKGLETPLKARQREMAEEQTKLQSQSLHTKNVFGTLQRHSGISSTLVSANNDNNSPHTPVTRKGYIPSSKYAYMMNSQSPRGKI
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.
What are the official names of this protein?
Nucleoporin POM34, Nuclear pore protein POM34, Pore membrane protein POM34.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Multi-pass membrane protein. Note=Central core structure of the nuclear pore complex.
Protein: APOC3_PHOVI
Sequence: MQPRVLLVAALLVLLASARALEAEDPSLLGLMQGYMQHATKTAQDTLTSVQESQVAQRARDWMTDGFSSLKDYWSTFKGKFSGFWDSASEVQPTPASDAS
What is the function of this protein?
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma.  Plays a multifaceted role in triglyceride homeostasis.  Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs).  Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.  Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners.
What are the official names of this protein?
Apolipoprotein C-III, Apo-CIII, ApoC-III, Apolipoprotein C3.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NQO14_THET8
Sequence: MTLAILAVFSVALTLLGFVLPPQGVKRATLLGLALALASLLLTWGKPFAFGPYAVDGVSQVFTLLALLGALWTVGLVRSGRFEFYLLVLYAALGMHLLASTRHLLLMLVALEALSLPLYALATWRRGQGLEAALKYFLLGALAAAFFLYGAALFYGATGSLVLGAPGEGPLYALALGLLLVGLGFKAALAPFHFWTPDVYQGSPTPVVLFMATSVKAAAFAALLRVAAPPEALALLVALSVVVGNLAALAQKEAKRLLAYSSIAHAGYMALALYTGNAQALGFYLLTYVLATGLAFAVLSQISPDRVPLEALRGLYRKDPLLGLAFLVAMLSLLGLPPLAGFWGKYLAFAEAARAGAWGVLVLALVTSAVSAYYYLGLGLAVFARPEETPFRPGPPWARAAVVAAGVLLLALGLLPGLVLPALAAGG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient required for the synthesis of ATP.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit 14, NADH dehydrogenase I chain 14, NDH-1 subunit 14.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMM_PSEAB
Sequence: MNTLLMHCRPGFEGEVCAEIAEHAATLEIPGYAKSKPASAHVEFVCQDADGAERLMRRLRFADLIFPRQWARGPGFIELPESQRIEVLLAELASYPVCGSLWLEVLDTNAGKEVSTFCRKFEKPLRAALVKAGRLQEDPALPRLLLTFRSGREVFVGLAEPRNSALWPMGIPRLKFPREAPSRSTLKLEEAWHQFIPRSEWDKRLAPDMLAVDLGAAPGGWTWQLVNREMRVTAVDNGPMAENLMYSGLVDHQKVDGYQYRPRQRVDWMVCDIVEKPARTGALIETWIGEGLCREAVVNLKLPMKQRYAEVRKILQRLRESFDARGLKVVIGCKQLYHDREEVTCHLRRLER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_ECO24
Sequence: MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDPA_ECOL5
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELHRVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGFVLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADRSTLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGN
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL19_HELPJ
Sequence: MKNRYIQQFEDAQLKDKSMPTFKAGDTLRLGITIKEGEKTRTQYFEGVCIAIRGNGVDKTFCVRKIGANNIGVEKIFPFYSESLASVEVLRVGRVRRAKLYYLRDRRGKAARIKEVRH
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: GLK_ECOK1
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEGIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What is the function of this protein?
Not highly important in E. coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate.
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_PROMS
Sequence: MAVPKKKKSKSKRNQRHAVWKGKAAIAAQKAISLGKSVLTGKAQGFVYPIEEEEEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: PURR_HAES1
Sequence: MATIKDVAKMAGVSTTTVSHVINKTRFVAKETEQQVLQAIKNLNYSPSAVARSLKVNTTKSIGMIVTTCETPYFAEIIHSVEELCYRQGYSLFLCNTQNNPEKIKNHLDMLAKKRVDGLLVMCAEYTQNSLNLLATFEDLPMVVMDWGPFNENTDLIQDNSFSGGYIATKYLIDNGHKDIAIISGELKKTTAVMRYQGFEKAMQEANLAINPDWIMEGFFEPEDGYECMNKILVQDKLPTAVFCCNDVMALGAISAIGEKGLKVPDDISVIGYDNIHASRFFSPPLTTIHQSKSRLGVQAINLLFKRISEKGKEHEIIEIYPELVIRKSVKTL
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: DHAS_AQUAE
Sequence: MGYRVAIVGATGEVGRTFLKVLEERNFPVDELVLYASERSEGKVLTFKGKEYTVKALNKENSFKGIDIALFSAGGSTSKEWAPKFAKDGVVVIDNSSAWRMDPDVPLVVPEVNPEDVKDFKKKGIIANPNCSTIQMVVALKPIYDKAGIKRVVVSTYQAVSGAGAKAIEDLKNQTKAWCEGKEMPKAQKFPHQIAFNALPHIDVFFEDGYTKEENKMLYETRKIMHDENIKVSATCVRIPVFYGHSESISMETEKEISPEEAREVLKNAPGVIVIDNPQNNEYPMPIMAEGRDEVFVGRIRKDRVFEPGLSMWVVADNIRKGAATNAVQIAELLVKEGLI
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: TET5C_HUMAN
Sequence: MAEESSCTRDCMSFSVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSRLEEAGIKVHDVRLNGSAAGHVLVKDNGLGCKDLDLIFHVALPTEAEFQLVRDVVLCSLLNFLPEGVNKLKISPVTLKEAYVQKLVKVCTDTDRWSLISLSNKNGKNVELKFVDSIRRQFEFSVDSFQIILDSLLFFYDCSNNPISEHFHPTVIGESMYGDFEEAFDHLQNRLIATKNPEEIRGGGLLKYSNLLVRDFRPTDQEEIKTLERYMCSRFFIDFPDILEQQRKLETYLQNHFAEEERSKYDYLMILRRVVNESTVCLMGHERRQTLNLISLLALRVLAEQNIIPSATNVTCYYQPAPYVSDGNFSNYYVAHPPVTYSQPYPTWLPCN
What is the function of this protein?
(Microbial infection) Seems to enhance replication of some viruses, including yellow fever virus, in response to type I interferon.
What are the official names of this protein?
Terminal nucleotidyltransferase 5C, Non-canonical poly(A) polymerase FAM46C.
What is the protein family that this protein belongs to?
Belongs to the TENT family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Recruited into the centrosome through its interaction with PLK4.
Protein: ABIG2_LACLC
Sequence: MAKSKFKTTFSNDKATTSSTALLKYINKKAPKGYKYEILYKGSDIYSLKKDNTDEKISFLVRFKFPLNFEGIKVTNPQDLLELSYRTQKEIVLDETLQNGSDGQPPTLVSLKGEVGKQSIFPIPFPKLDPIKLEWFGGALEIPIKRIPYASLSEIKLESESDNILHVSFLFNETNNKVHLNTNINFEYLRTIDDYFKFRDFLKNYSEGRVKILSKNITLRSEDNNDKIKIFEKNDKLYNALRLIQSKIDTKIPFPQNLSIKDVNIIKILFESYINDRVVKFKSEPSLKFTFDDSSNFKESFPITGKKNMGIFVPFQRNIKFLSVSIPIIENQLYTDTTVKTADLQDRVLILETNKNNESFVFYQNSEEYKEISINEMLEKKKAAIELDDIDFSVLKK
What is the function of this protein?
Confers resistance to phages by a mechanism of abortive infection.  Seems to act by interfering with phage RNA synthesis.  Does not act at the level of phage DNA synthesis.
What are the official names of this protein?
Abortive phage resistance protein AbiGii.
Protein: ENGB_PHOV8
Sequence: MEILSAEFVVSNTKVEKCPQDNLPEYAFIGRSNVGKSSLINMLAKRPKLAMTSSTPGKTLLINHFLINKEWYLVDLPGYGYASRGKKQVEKIQQIIEDYILEREQMTNLFVLIDCRLEPQKIDLEFMEWLGENGVPFSIIFTKADKLTNGKVKDNVNKYLKKLTEQWEELPPHFVSSSEKKTGRQEILDYIDSINRSLKA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NEPI_SALCH
Sequence: MNENIAEKFRADGVARPNWSAVFAVAFCVACLITVEFLPVSLLTPMAQDLGISEGVAGQSVTVTAFVAMFSSLFITQIIQATDRRYIVILFAVLLTASCLMVSFANSFTLLLLGRACLGLALGGFWAMSASLTMRLVPARTVPKALSVIFGAVSIALVIAAPLGSFLGGIIGWRNVFNAAAVMGVLCVIWVVKSLPSLPGEPSHQKQNMFSLLQRPGVMAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFDVDGLTLVLLSFGIASFVGTSFSSYVLKRSVKLALAGAPLLLALSALTLIVWGSDKTVAAAIAIIWGLAFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAVGGYALDNFGLLSPLALSGGLMLLTALVVAAKVRITPMS
What is the function of this protein?
Involved in the efflux of purine ribonucleosides, such as inosine and guanosine.
What are the official names of this protein?
Purine ribonucleoside efflux pump NepI.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EX7L_MYCTU
Sequence: MTQNSAENPFPVRAVAIRVAGWIDKLGAVWVEGQLAQITMRPDAKTVFMVLRDPAADMSLTVTCSRDLVLSAPVKLAEGVQVVVCGKPSFYTGRGTFSLRLSEIRAVGIGELLARIDRLRRLLDAEGLFDPRLKRPIPYLPNMIGLITGRASAAERDVTTVASARWPAARFAVRNVAVQGPNAVGQIVEALRELDRDPDVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPVVSAVGHEPDNPLCDLVVDLRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRAVAQLRSRPVLADPMTMVSVRAEEVHRARSTLRRNLTLMVAAETERIGHLAARLATLGPAATLARGYAIVQTVAQTGPEGGSEPQVLRSVHDAPEGTKLRVRVADGALAAVSEGQTNGL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPH_ACOCL
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y486_SHEDO
Sequence: MKLVIVSGRSGSGKSVALRVLEDLGYYCVDNLPLPLIGSLLAQLKSSNDLVAISVDVRNIAEQGKVLEQQLALLPPETEISSFFLNSSDKVLLKRFSETRRLHPLSRSQMSLQEAIKLEGRLLEPIAKMVDHHIDTSLLNVYELSDQVRQILLGSVDKELVINIESFGFKHGMPTEADFMFDVRFLPNPHWETELRPLTGLDVPVQEFLARQPLVHKLIWQIENLFETWMPHLERNNRSYLTIAIGCTGGQHRSVYIADQLAKRFANGKHVVNARHRELGDVKA
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Sden_0486.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: DDL_PELTS
Sequence: MTLKVGVLMGGRSSEREVSLKTGEAVYNALKVKNYLAVKIDVGLDVVERIKEERIDLAFIALHGRYGEDGTIQGLLEMLDIPYTGSGVLASALAMDKAATKKIIQYEGLPTPPFMLVEKKEALKESLQACSERICREMGLPLVVKAPTQGSTIGMSFVHKEEDMAGALELAYDYDPVALVEQFIRGTEVTASILGNEEPVALPLIEIVSATGVYDYKAKYTAGMSDHIIPPRIPEKQQNAIKKLAVSTFKSLGCRGLARVDFIVDKQGNPFILEVNTIPGMTATSLFPDAARAAGIEFPDLIEKLVELAMENCGIRRR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_ECOL5
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: UP06_PINHA
Sequence: ARVPFYRYYK
What are the official names of this protein?
Unknown protein 6.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: SYY_MYCPU
Sequence: MSQNKLKTLIEELKKRKVFNNITSEEKVDLITLDHGIYVGFDPTAISLHLGNYIQMVNLKRFQNVGFKTIAILGGATSMIGDPSFKDSERKLLSNETILENKKHIRKQLENFGFKVIDNLDFYKDMNILDYLRSVGKFFNVSTMMSRDSVANRIQSGLSFTEFSYQTLQAYDFKVLCEKENVMMQLGGSDQWGNLVSGLDFINKTLSKNLPTIGITMNLLVDSNGNKIGKSTGGASLWIDKTLTSPYVLYQYLLNTNDDDAYNLLLQLTFLQLSEIERIKNEHLKNPKLRLMQSRLSFEVVKDIHGKEEAQRALHISTSLFKEKNSWFNLSLEDLIQLKGSVDFVPFKDDLFLTLVDSKIISSKREFNEFVRDKSLKINGQDVTGLDYDLPWENYDNKYLILKKGKKQYWVIYK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.