PharMolix/UniProtQA huggingface dataset:
Protein: RS20_STRP2
Sequence: MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELFRAASSAIDKAETKGLIHKNKASRDKARLSAKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ACFD_VIBCH
Sequence: MKIRIVSLIVLGFLIGCKHESIITPTVPADGSGGNALNPGLVGGYLPDIGVPDPIISLSMTLDGNLKFDSSLLCNDQDASHFQISQKDNVFCTINGRSIATFTAPFDANKNGRNTDSEVLSLISADEYRDSPVRQENLQILMKNMATIHGDKISLVFRSTLDALTFENYLRHNLDLPKDQFLEAITEKIANDNQVDKQPSTHVPNISPSFTPGTSSNLNSPFVSANAEESLSYIPTDVIPSLGRLLDSQGRVINGVSYFSNNTRGITGVDKTGAILNDGSFEFSWGDIISFSIDTFELGSTRANKTDFYISELGKDNEGKNAEALIHRYASIDDSKLIIPDKVTQIFSLYPNVINEVISLSLPNGDIELDIGDGKTQIVPGEFFKQFDSGLAALIDQSISPISRFKFEDSLPKKKSAIDSESSQIQDIINKLWGATDTVQANGWKKVDRFHIFHDSTNFYGSTGSARAQAAVNIANSAFPVLMARNDNNYWIDFGKPKAWDSNSLAFITEAPSTVVPDKVSEDTSTFNLPFISLGEIGKGKLMVLGNARYNSVLVCPNGFSWGGTVKNGTCSLSSDRDDMANFFSNVIRYLTGSTSNDVIVGTNIPEVYFKSSGQTMGSKANFELDSRFSKQTQQLTSFHDLDVNTIPLIIINAYDYKGKNINSPYDIPLSADVGSPKLSRSDVTDLIDYINNGGSVLMMETIINTNNSEISRLLDSAGIAFGIGNSVVADGNGPSGGHPDRPRSQREHGIWVIERYAAVEDESSGQQTLPYVINSDGSIEWKYIVENRPDDKPKLEVASWVESEAGDKLITHYAFIDESQHWKKDISGKIIYNVAGKPEVDNASLSLAKNKVLDAFKNSSGQRAYSECKNSEFHYEINCLEYRPGNSIPITGGLYVPRYTDIKLGESEANAMVKAANLGTNIHALYQHERYFRTKGKSGARLNSVDLNRIYQNMSVWLWNDLDYRYDDKQSDELGFKVFTQYLNCYTSNNAGGNTTCPEELKDELTQLGMIYDEKSGSYAGQMDPSYPLNYMEKPLTRLMLGRSFWDLDIKVDVRKYPGEVTTRSGGGDITLDMRNNTAAWFAGNRQPTGQWAEAHQPFSVSVSGETSPVTITIALADDLTGREKHELGLKRPPRMSKSFVIGGDSPKMQTFTVPYGGLIYAQGGNSQQVKLTFSGTIDAPLYIDGKWRNPLLSGAPIGEVVSDTFIFTAPKANLNADGYLGGIEQFAKDLDQFSADLNDFYARDEGADGDKNRKATDKSMPNNRHHFVNDVAISVGAAHSGYPVMNDSFITSSRSLNTMPLNSWLLWHEVGHNSAEAPFNVDGATEVVNNLLALYMQDRHQGKMSRVEQDIRYAFDFVNAEHGHAWGAGGAGERLVMFAQLKEWAETEFDINDWYNDKLPGFYIEESGIKGWNLFKLMHRLMRNENDDQINMKGENQCKISGIGKSDLLMLCASYAAQTDLSEFFKAWNPGSKAFLYPDDPQPYYEGGITPSGIQRVKSLKLNLPQKNPLSINSVTQH
What are the official names of this protein?
Accessory colonization factor AcfD.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PYRDB_SOLM1
Sequence: MSVDTSVRLPGMPVKNPVMTASGTFGYGLEFAPYGDLRSLGGIVVKGLSLAPRLGNPMPRIAETPCGMLNAIGLQNCGVEKFLRDKLPRLPWRETPIIANLYACDADEFAELAGVLSAEEGVAALEVNISCPNVKAGGIAFGQDPCMAGKLAEAVKKRAGDKPVWVKLSPNVTDIVSIARAAVLGGADALTCINTLTGMSVDIRSRKPRLANVIGGLSGPAIKPVALRAVWQVCQAVSAPVIGVGGISSAEDVLEFILVGAHAVQIGTANFMRPDMAFRIAERLPQLMAELGIEDLASYRGSLRVG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETN_PANGI
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL3_AYWBP
Sequence: MAQGILGKKIGMTQVFNEQGELVPVTIVDVAANVVLQQKNVDQDGYQATQIGFCDKREKNTSKPMLGHFKKATTAPKRFIKEINFSSDVNSNLANLVVGALITNDLFQVGDLVDVTGTSKGKGFAGSIKRHNQSRGPESHGSRYHRRPGSMGPIKGKLKGKKLPGHMGYETVTIQNLAILSIDTEKNLFLIKGNVPGPNKGFVMIKSAVKKLTKEQTHAKN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PG053_VACCP
Sequence: MAETKEFKTLYNLFIDSYLQKLAQHSIPTNVTCAIHIGEVIGQFKNCALRITNKCMSNSRLSFTLMVESFIEVISLLPEKDRRAIAEEIGIDLDDVPSAVSKLEKNCNAYAEVNNIIDIQKLDIGECSAPPGQHMLLQIVNTGSAEANCGLQTIVKSLNKIYVPPIIENRLPYYDPWFLVGVAIILVIFTVAICSIRRNLALKYRYGTFLYV
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
EFC-associated protein OPG053, Protein F9.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG053 family.
Protein: YIDC1_STRPQ
Sequence: MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVYLFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQRKYAGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTFLWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNLASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 1, Foldase YidC 1, Membrane integrase YidC 1, Membrane protein YidC 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCED1_ARATH
Sequence: MSLVCSLSCVAPLPQTKQSRPSFLKLETCTLSLSSPAGYPNFTTGIRKHISYLFTEPIKLPRLAKSRILVSQESFTETSTIDMDWEDQEEIEDTGSPWEGSVMYRRNASVTHVEYCTTLERLGLGRLSTDVSKKRASAMGLRVTKDVKDYPDGTPVQVSVDVIRKKKKLRLDGIVRTVITLGCNRCGESTGESIFSNFSLLLTEEPVEEPDVIDLGFTFGNDKEEGEDDDDNDDSWIDWEDKLHFPPEVKEIDISKHIRDLVHLEITITAICDSACKGMCLKCGANLNKRKCDCGREEKDKGYGPLGNLREQMQQKEGLRN
What is the function of this protein?
Plays a role in synthesis, processing and/or stability of 23S rRNA.  Required for embryogenesis.
What are the official names of this protein?
Large ribosomal RNA subunit accumulation protein YCED homolog 1, chloroplastic, 23S rRNA accumulation protein YCED, Protein DUF177A.
What is the protein family that this protein belongs to?
Belongs to the DUF177 domain family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma, chloroplast nucleoid.
Protein: TYSY_PSEPK
Sequence: MKQYLDLVRDVIDNGTLQGNRTGIRTISLPGAMLRFDLQKGFPAITTRKLAFKSAIGEMVGFLRGVKNAGEFRELGCKVWDQNANENAQWLANPFRQGHDDLGEIYGVQWRQWPGYKRIPLSNPAAIEMAEQAGFRRIAQDEEDGVAFVILYKAIDQVRQCLDTIANDPGSRRILFHGWNCAQLDEMALPPCHLLYQFHPNVETREISLTLYIRSNDLGLGTPFNLTEGAALLSLFGRLTGYTPRWFTYFIGDAHVYENHLDMLNEQLKREPLEAPKLVISDRVPAFAETGKYEPEWLEKIEPSDFWLEGYEHHAPMTAPMAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_STRTD
Sequence: MSRYTGPSWKQSRRLGFSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFSYGLSEKQFRNLFVQATKVKGGTLGFNFMILLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVEVGQVISVREKSAKVPAILEAVEATIGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS20_TREDE
Sequence: MKNRSAIKRHNQSEVRRMRNRSAKSEVRTTARKYTEAVHAANAENAAALLRELSSQLDSAARKGILTKNSAARKKSRMQLLYNASFAAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: DXR_ACIBS
Sequence: MTQSVCILGVTGSIGQSTLKILGQHPDKYSVFAVSAHSRISELVEICKQFRPKVVVVPEQKIAELKTLFAQQNISAIDVLAGQEGLVDIASHTDVDIVMAAIVGAAGLLPTLAAVKAGKRVLLANKEALVMSGEIMMQAARDHQALLLPVDSEHNAIFQSLPHNYLQADRTGQPQLGVSKILLTASGGPFLNHSLEQLVHVTPQKACKHPNWSMGQKISVDSATLMNKGLELIEACHLFSISEHFVTVVVHPQSIIHSMVQYVDGSTLAQMGNPDMCTPIAHALAWPERLQTNVPALDLFEYSQLNFQAPDTQKFPALNLARQAMRAGGLAPTILNAANEIAVEAFLMERIGFTSIPQVVEHTLEKLENTAAESIECILDKDKVARSVAQQYIKYWRLK
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: CATK_MACMU
Sequence: MWGLKVLLLPVMSFALYPEEILDTHWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTNEEVVQKMTGLKVPASHSRSNDTLYIPDWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
What is the function of this protein?
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling.  Displays potent endoprotease activity against fibrinogen at acid pH.  May play an important role in extracellular matrix degradation.  Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
What are the official names of this protein?
Cathepsin K.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Secreted. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells.
Protein: BZP39_ORYSJ
Sequence: MAEPALLDPTAAFDLRLYPAHLFDHELPLAGGGGGDDDDDLPLDGLEFDLPGDFSVEDFLLRSPERDDSGEGSAAGSGPTASPSSSPTTSASNSAVANGSGGEVKHEESDEGRSGGGDPKWSLKRKQASPGPSSDAAKCRRSGDGDVSPSASASRTAVDSDEGGTVCEEEEDERRAARLMRNRESAQLSRQRKKRYVEELEEKVKSMHSVINDLNSRISFVVAENATLRQQLSGGSVNCPPPGVYPPAPIPGMHFPWMPGYAMRPPGSHVPLVPIPRLKPQQPVPSSKVVKKPESKKTVENKSKSKTKTKKVASVSLLGLLLIMLVFGAFIPGFNHNFGMCGQSDNAMFRNFGQSHARVLSVSSQDKSSLNNSDMIGVDVGKMTGNTDGPGKKHQPAHNSSEILPALLYVPRNGKHVKINGNLIIHSVLASEKAVAHKASKDDSDQSARDHKETSVAIARYLSLPGKDVNRQETSSADGPLPQWFREGMEGPILNSGMCSEVFQFDISTASSNPGGIIPASPVVNSSSVNATEKIPAHSAAYHGKLKNRRVMYNEAIPLTGKTANNTEPFNRTSESSSKLPDSKPASSVVVSVLADPREAGNGDGDPRVSPKPLSKIFVVVLVDGVRYVTYSCTLPFKSSSPHLVN
What is the function of this protein?
Transcription factor involved in endoplasmic reticulum (ER) stress response.  Acts as ER stress sensor and activates the transcription factor BZIP50 and the chaperone BIP1.
What are the official names of this protein?
bZIP transcription factor 39, OsbZIP39.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus. Note=The bZIP domain is translocated into the nucleus in response to ER stress.
Protein: SYL_LEGPC
Sequence: MDNTYNPQEVEEQAQQYWHKKQSFNVTEDLNKEKFYCLSMFPYPSGTLHMGHVRNYTLGDVIARYQRALGKNVLQPIGWDAFGLPAENAAIKNKIPPAEWTRKNIAAMKEQFLRLGNAYDWKRELTTCDPEYYRWEQWFFIRLFEKGLVYKKNAVVNWDPVDQTVLANEQVVDGRGWRSGALVERKEISQWFIKITSYADELLSSLDSLDEWPAQVKQMQRNWIGKSIGTEIYFNVNNYPKRLKIYTTRPDTLMGATYLAVATDHPLAKEAASNNKKVQEFLDSCQGIKIAEAELATMEKRGIDTGMTAIHPITGKELPIWVANFVLMQYGSGAVMAVPAHDQRDWEFAQKYQLPVKQVIKPIDIEHDFNQSAYTEEGILINSNQFDNLLSSKAIQVITNFLEENDAGKATINYRLRDWGVSRQRYWGTPIPMIICEQCGIVPVPDEELPVVLPENVDFTGTGSPLTQCKEFVNVTCPKCGQDATRETDTFDTFVESSWYYARFACKGQENAMLDDRAKYWTPVDQYIGGIEHAVMHLLYARFFHKLMRDEGLVNSDEPFKALLTQGMVLKDGHKMSKSLGNVVDPNHLINTYGADTARLFVMFASPPEQSLEWSDSGVEGAHRFLKRVWAFSHQHRDMLIDINDSILSGNGHVDWKEAESRLKKSRHIVHQILAQATHDYDRNQFNTVVSGCMKLFNEISDYSIETENDKFFIHSSISILLRLLAPITPHICHCLWQQLGFDKAIIDAPWPKVDKSALKTDEVDYVVQVNGKLRAQFTASTDATEEELIAAAKEHAHNFVVNHTIKKAIIVPHRQLINLVIG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_BACAC
Sequence: MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTATADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLEECGVEILGTKLSAIEQAEDRDLFRTLMQELNEPTPPSEIIHNLDEAYGFVNEIGYPVIVRPAFTLGGTGGGICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGCKEIEYEVMRDSNDNAIVVCNMENIDPVGVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRWPFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELDHLKELDKETMKKRIIKADDERLFIVAEAIRQGVTKEEINEWCEMDFFFLQKVENIVNMEREVKANVGNMEVLQTAKEMGFSDHYIAAAWNKTEREIYDMRKENNMTPVFKMVDTCAAEFESATPYYYSTYADENELIVTDRKSVVVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIIINNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLEEHGVKILGTSLEDLDRAEDRDKFEAALTKLGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYVLGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVFIPGIMEHIERAGVHSGDSIGVYPPQSLSEKLKEQIIEHTIALGKGLNIVGLLNIQFVVFKDQVYVIEVNPRASRTVPFLSKITGVPMANVATKVILGQDLVEQGYGTGYHPEEKEVYVKAPVFSFAKLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVASGINIPTHGSVIITVADKDKEEAMEIAKRFHEIGYNLLATAGTAQSLTEQNIPVQVVNKIDSEDYNLLDIIRQGKAQFVINTLTKGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHSMKEITQTKRHEVVHA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: NDK_BARHE
Sequence: MAVERTFSMIKPDATRRNLTGAITKMLEDAGLRVIASKRVWMSQREAEKFYAVHKERAFFSELVELMSSGPTIVQVLEGENAIAKNREVMGATNPEDAQEGTIRKVHALSIGENSVHGSDSAETAKTEIAFWFSEVEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_ACIAD
Sequence: MELTLGLVAIASAILIAFGALGTAIGFGLLGGRFLEAVARQPELAPQLQTRMFLIAGLLDAVPMIGVGIGLFFIFANPFVG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PG061_VACCW
Sequence: MKVVIVTSVASLLDASIQFQKTACRHHCNYLSMQVVKEIEEFGTINEKNLEFDTWKDVIQNDEIDALVFYRVKQISISTGVLYKSMMRNRTKPISMYFVRDCLAFDGDPPSFRMTSCNINAYNRSKIKDLIILMNMKTCNKKIIGEFIIDNFGSVDALLSIINSNVTWITSVINNSNGRGINIRVSNNKMLTITSFRRFVNKLKMYKTTKCASQLDNLCTEMNKMDIIDKK
What are the official names of this protein?
Protein OPG061, Protein F16.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG058 family.
Protein: RPOE_LIMRD
Sequence: MDLKVFDGQDKSELSMIEVAHAILAHHGKAMAFVDLTNEVQQYLGKSDEEIRERLAQFYTDLNVDGSFISLGDNTWGLRAWYPFESIDEATVGENEEDEEDDRPKKKRRKVNAFLADTDDDDDVIDYDNDDPEDEDLDTDDDADSEDDYDDDTDDFSDDDDDLDDGIEGQLSELHDEEDEDEDDE
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: MURE_WOLSU
Sequence: MKVFSHQDEVEFISDDSRECTPKSAFLLTQSSRVYEAAAREKGCKLFLEPKDLHRFLKTDIPLIGVTGTNGKTTTSAAIYSILLDLGYKVALLGTRGFFMNDELIEPKGLTTPPLLELYERIDRAKRAGCDFFVMEVSSHAIDQKRIEGLNFALKILTNITSDHLDYHKSLEHYIQTKNSFFDDSTPKLINKDESKAKFNLQNALSYGIEHPSSYHVKAYSLHGGIEARIAFLEKEASLSSSLFGKHNLYNLLAAVSAVHRLIGGELQEICDMAERFGGVEGRMERVSEEPLVVVDFAHTEDGMRQIFESFPHQEIVVLFGAGGDRDRSKRPKMGAVADRYAKRIYLTSDNPRSEDPLLIIEEIEKGIHHCQKCVKEPDRVQAIRRAVKELEAQEVLLILGKGDEAEQIIGSQKIPMKDRETVLSALGEIRGVR
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_ECOUT
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: HTN_HAEGH
Sequence: TTLTEPEPDLTYLTFVXIVXXEMPIFVMATANSGITSTF
What is the function of this protein?
Metalloprotease with anticoagulant activity.  Cleaves fibrinogen Aalpha (FGA), gamma (FGG) and Bbeta (FGB) chains after positions 'Asn-121', 'Lys-160' and 'Pro-102', respectively.  Breaks down cross-linked and non-cross-linked fibrin clots.  Prevents and reverts platelet aggregation induced by ADP and collagen.  Prevents thrombin-induced platelet clotting.  Does not affect plasma levels of coagulation factors prothrombin (F2), V (F5), VII (F7), VIII (F8), IX (F9), X (F10), XI (F11), XII (F12), plasma kallikrein (KLKB1) and kininogen-1 (KNG1).
What are the official names of this protein?
Hementin.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRB_ACIB3
Sequence: MHIAALHQPSQVQLNQDGNLKHFLTIEGLSKENLTKILDTAQSFLDDNNNLINRPLLEGRTVMNLFFENSTRTRTTFEAAAKRLSANVLNIDIARSSTSKGETLRDTLWNLEAMAADIFVVRHSSSGAAHFIAKDVCPKVAIINAGDGRHAHPTQAMLDMLTIRRETKKSFEDLSVAIIGDIKHSRVARSDVAALQTLGCKDIRVIAPNTLLPVGFSEYGDHVRLFNNMDEGITGCDVIIALRIQNERIDSPALSSQSEFYRMYGLNKERLSLAKPDCIVMHPGPMNRGVEIDSSIADGEQSVILKQVTNGIAVRMAVLALSMQGQLQEQGLIEAIAL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MUTL_SHEB8
Sequence: MMGIQILPPQLANQIAAGEVVERPASVVKELVENSLDAGASRVDIEIDKGGSKLIKIRDNGSGIPKDELALALSRHATSKLHTLDDLEAILSFGFRGEALASISSVSRLTLTSRTADQTEAWQAHAEGADMAVKVMPAAHPVGSTIEVVDLFFNTPARRRFLKSDKTEFTHIDEWLKRIALVRGDIHFTLTHNGKTVRNYRPAMNEAQYLQRLTQVSGRPFAEQALKIECQHDDLRLSGYLQSPWSPVITDTHYFYVNGRLIRDRLVNHAVRQAFAQKAELEQPGYVLMLDIDPHQVDVNVHPAKHEVRFHQSRYVHDYILQALQSALEEAGELNVVHSSSLDEVEDVFVDSPTSAVGIAAPFALGADTLESAQPLVASAAVQVKSAGAGREGASFGTQTNAFGSMATSRDSSRGSYSASESRQRTELPSKAAIASYGALLQTPAYSVKNHDYQPSLPMPAILDSQYWVMATADKLSLLPIKSVALATRCQEIEAKLATGLIGQPLLMPVSVAADADWQAVLDEHDTLIRQLGLELTIRYQQLIIKKVPPYIRESQLAKVIPEWLQSLRFETPAPSALAFWLAKHSLTGFVSAPEIWAAFSQLAEEKKQLIANKAILLPWQSWLEEQASE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: CP2J2_HUMAN
Sequence: MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRMGITISPVSHRLCAVPQV
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA) in the cardiovascular system (PubMed:8631948, PubMed:19965576).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:8631948, PubMed:19965576).  Catalyzes the epoxidation of double bonds of PUFA (PubMed:8631948, PubMed:19965576).  Converts arachidonic acid to four regioisomeric epoxyeicosatrienoic acids (EpETrE), likely playing a major role in the epoxidation of endogenous cardiac arachidonic acid pools (PubMed:8631948).  In endothelial cells, participates in eicosanoids metabolism by converting hydroperoxide species into hydroxy epoxy metabolites.  In combination with 15-lipoxygenase metabolizes arachidonic acid and converts hydroperoxyicosatetraenoates (HpETEs) into hydroxy epoxy eicosatrienoates (HEETs), which are precursors of vasodilatory trihydroxyicosatrienoic acids (THETAs).  This hydroperoxide isomerase activity is NADPH- and O2-independent (PubMed:19737933).  Catalyzes the monooxygenation of a various xenobiotics, such as danazol, amiodarone, terfenadine, astemizole, thioridazine, tamoxifen, cyclosporin A and nabumetone (PubMed:19923256).  Catalyzes hydroxylation of the anthelmintics albendazole and fenbendazole (PubMed:23959307).  Catalyzes the sulfoxidation of fenbedazole (PubMed:19923256).
What are the official names of this protein?
Cytochrome P450 2J2, Albendazole monooxygenase (hydroxylating), Albendazole monooxygenase (sulfoxide-forming), Arachidonic acid epoxygenase, CYPIIJ2, Hydroperoxy icosatetraenoate isomerase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.