PharMolix/UniProtQA huggingface dataset:
Protein: SYH_ORITI
Sequence: MSIKLQPVKGSKDLLPEEFGKHDYIVSVSRNLSQLYGFQPISTPIIEYTEIFNRTLGKDSDVLSKEMYVFLDKGNRSVSLRPEFTASIMRAVIYNNLQNKKLPLKYFSSGPAFRYDNPQAGRQRQFHQINLECIGDDSPFSDAEIVLLAHDILKTLNLVDKVNLEINSLGCMESRAKYQQALVEYFSKYRTELSQDSQSRLIENPLRILDSKNLHDKKISASAPSIHDYYTIKSRCYFDKVLEYLEFCGIKYTINANLVRGLDYYCHTVFEYTSTQIGAQSTVLGGGRYDGLFEQMGGKLASGKKTLPAIGFAAGIERLALLTNYTPVDVRPIVIIPVDEEHHQHGIMLLQKLRNNNITTVIDLQDSISKRLNRANYIKASKVIFIGAIEVREQSYRIKDLDTSNECVIIHNELLSYLQNNCS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_RUMCH
Sequence: MSEYTKQITRLISEVRSKKPLIHNITNYVTVNDCANVTLAIGASPIMADDIDEAADITSISSALVINIGTLNKRTIESMILSGKKANEKGIPVIFDPVGAGASALRNETTSTILDKIKISVLRGNLSEISYIAGRNASTKGVDASEADIQSNDSIAVAKAAAVKLGCVVAVTGAVDVISDGKNVVTVLNGHKMLSNVTGTGCMTTALVGSFCGAVKDYFKAAVAGVTVMGISGEIAYEAAGHKGTGSYHIAIIDAISRMDENIFGEKARINEI
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: Y195_BPT3
Sequence: MLRLLIALLRHRVTWRFLLVLTATLGYAGLNDHLGQLEVAFCSILSCGD
What are the official names of this protein?
Uncharacterized gene 19.5 protein.
Protein: VILD_DICDI
Sequence: MEYKSIEKSIVRESKVRNVFSKVCKKELFYTNLKVNSASEELLKSSKSLFAYPSSIGGGSCLSITKLSNHGKVPDTPFCIKGHTDPISCFEFSNFNDYVIATGSRDCTIKIWEVPEEGLIKDNLVTPLITLPKQQKRVTGVYFHPSVDSLFMSSTLDYTLDIWDLSSTGEQSSVIQKLTGHEDLIMSVGWNTWSGGDKLATSSRDKKMRLYDPRSQSTPIQTISTHEGAQGFKLCWADSNGLELICTVGANKSAQRQLYLWDPRQLQSSQPLVSKDVTTDSSILSPYYDFGTNMVYLGGKGDGIYYYEIEKNNAHHIGKATFGNVTQSAITLLPKSVVDVNICEIDRFLRLTAANSVEMVSFMCPRKSQLFQEDIFPPCPSGDPTTDCSLWFADKQLKVIPHTISMKPDGVQSIYEVSEEEGGKSKEKDKLEQLSKLSIGNSGSGGGGGDGDGNGGDSPFITEGIVKQEIEGWLFNSYENRYLKIVKDKIYCFLNEDSAQAIWDSPVLNIKYVDIYDEDENTSGEEWSLRFNIILLNGKEHRMECSTVKQRDAWCQSINAYREMKQQVDQSVVSPTMGEFHLVNTTPVAPSPMVISENKNALQKFSVPSPKEQQQQQQQGSESPNSTTPKSSTPTQTRHHSVLSRNPSYTSLKSSGGFSKPSPSSSTSTPPSTFASPLSIAQTSSTTTTTTTTTTTTSSSSTPPPLRANNSTSSTPLNSSTGIKQSDIVIEGNLTELIPGLLWNSNTEKWYVVSEGMLYSYKNKSLKQLDPLETIHLEKAISAHKTKEIFTIQGFSFQLSTPNRIIHLLAKTKEERGSWLSVLRQNLKSSGETKPKSVLTRASTMDELISSPMSDDESNTNEGGVEEEEEEQPLEGQLSRKLPGIFSMWGQCFVALLAEDLFVSRNKLSTTPELRIQLSSISLIKKISPNEFTLYDSMNQVVCNFRTIAPTAEFDDCTRWIDGLEAARKRSIDIIKMFGINEKEVLSPLPSSSSIPSSGSNGNLLDPSADDLTRYLDLTAIKNGKQKILIQVKGKRKIRVRMVKLSTSSLNCHNSFILDAGPRIFVWAGSKTSRVNKAKALDFANRIRTKERGGKSTLIQLDQGRDEQSFDFWEILGGNSSDPIATTPTPEEQDTESIKTTIYRVGLDVKKNSLRARLAWEGTDWKLPNKEILNTKFVYVVDCVTEIFVWVGKESSSIQRKMATKVALVLQAQKDRVDWTKITRLTEFGENNLFKEKFANYPGMLPISTTRQEIKSHVATSKVEHKIETLASRMTTPFIDNEALFTIPIDEGGRVKVWKIEDYEKIDHPQHLYSQFFSSDSYIVLYTYMQNNKEAHVIYYYLGRDSSINEKGTSAYLTVDLNESLVGACVQTRVVANKECKNFLNLFKTKMVIHKGKYNNYDPKKPSLYQVKGLDKIDIRAVQVEFSSSMLNTLHVSILRTPEKIYIWHGKFSLDAEQNSALSIAENFNSTSAPIEILKEGSESNEFWSAFESTGGRQKYFNDIMIQSSSIPTSFTYKPRFFVCSNASGIVEVTEESPFSQDDLDIGSVCILDVQSHIYLWIGSRATHRTKRASMEVVLNFIETSKLGHSKEHTKVLIATPFEEPIGFKSYFRAWCTSKYPKNKLPLVEKDGIPVEQVLKDYLKEIYTYEELLADPLPAGVDSTKLDTYLNDEDFEKVFKMTRTEWLKIPAWKREGIKKELFLF
What is the function of this protein?
May function as a linker between membranes and the actin cytoskeleton.
What are the official names of this protein?
Villidin.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Associated with membranes and the cytoskeleton.
Protein: PYRB_BURCH
Sequence: MTTDTTGRTGNPAAAASPDRFRYGFLKGNPQLTKNGELKHLLSIEGLPRSIVNHILDTAEQFVSVTDREVKKVPLLRGKSVFNLFFENSTRTRTTFEIAATRLSADVLNLNINASSTSKGESLLDTINNLSAMHADLFVVRHASSGAPYLIAEHCAPHVHVINAGDGRHAHPTQGLLDMYTIRHYKRDFTKLRVAIVGDILHSRVARSDIHALTTLGVPEVRAIGPRTLLPGGLEQMGVKVFHNLDEGLKGVDVIIMLRLQNERMSGALLPSAQEYFKTWGLTPERLALAAPDAIVMHPGPMNRGVEIDSQVADGPQSVILNQVTFGIAVRMAVMGIVAGNSD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CSRA_GEOSL
Sequence: MLVLTRKMGEVVTIGDSIRIKVVEMKGNQVRLGIEAPNDMRIYREEIYIKVQRENQIAASWSLADLEKAVTCLGADGKE
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KN14C_ORYSJ
Sequence: MGTVNGEYEDFDAANRRAEVIDWLGGLLPEFDLPLDSSDEELRDYLINGEALCYVADKLMPGVLEGTWGGYASDQRSNVKKFLSVVAEMGLPGFGVKDLEEGSMSSIVECLLALKDNVATQLGGHISNSTAKTPIRRKLELRETDGPVLSVATPGKRYPKSQQRSPLLSGQKINEVVQFKHGTYTDLPAAKISEMLHSNSLDNAPTQSLLRVVNGILDESIERKRGEIPHRVVHLLRNVIQEIEHRIGIQADHIRNQNSIIKTREDKYRSKIKALETLVNGTNEENEMAINRLEVVKVEKSKIDEKRKLGEQDMIRLIREKENAENIIASLHQEMQVMNRMHEQFREQMETKARQMEEHLTLRAKEAEFCLMQSKKKVEEVEATSQLKSQLWSKKANIFQSFMNNQKLSIKDIKISSQSIKQEMYALQMTWRDEISNIGHDLKGLVDAAENYHKVLAENQKLFNEVQELKGNIRVYCRVRPFLPGQDGKLTAIDYIGENGEILIANPSKQGKEGYRMFKFNKVFGTHSSQAEVFSDIQPLIRSVLDGFNVCIFAYGQTGSGKTYTMSGPGTSREDWGVNYRALNDLFDISLSRKNAFSYEVGVQMVEIYNEQVRDLLSNDIAQKRLGIWSTSQPNGLVVPDASLHPVKSTSDVLDLMEIGQSNRAVGSTALNERSSRSHSILTVHVRGLDVKNGSTSRGCLHLIDLAGSERVERSEATGDRLKEAQHINKSLSALGDVIFSLAQKNAHVPYRNSKLTQVLQSSLGGQAKTLMFVQINPDIESYSETISTLKFAERVSGVELGAARSNREGKDIKELLEQVASLKDTIARKDMEIEQLQLLKSKSPNSMTDRNGSNLLRQSTSSTGLSSLPVASQQNQQLSGSVEAEAEDNASDDGCSVGETEYSPAGASETSAERAHKAPSRITRFFLTKNGQPSTSRPKPREVVPKTQGSMRPGTAQATGGSLAKPSKRR
What are the official names of this protein?
Kinesin-like protein KIN-14C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.
Protein: UBIA_VIBC1
Sequence: MSAEKAKAYWQLMRMDRPIGSLLLLWPTVWALVIAAQGMPSWNVLIVFVLGVFLMRSAGCVINDFADRKVDGHVKRTKQRPLPSGKVTSKEAIGLFLVLGISSFLLVLTMNPLTIKLSFAGIFLAFIYPFMKRYTYLPQLFLGLAFSWAIPMAWAAQTGELPWIVWFVFVINALWTIAYDTQYAMVDRDDDLKIGIKSTAILFGRHDKLVIGVLQLVTLAMLVLLGQHYELGQSYYWTILVAASLFVYQQHLIRHRERDLCFKAFLNNNYVGIVIVIGLLIAFW
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KATL1_RAT
Sequence: MNLAEICENAKKGREYALLGNYDSSMVYYQGVIQQIQRHCQSLRDPATKAKWQQVRQELLEEYEQVKSIVSTLESFKMDKPPDFPVSCRDEPFRDPAVWPPPVPAEHRAPPQIRRPNREVRPLRKDMGAGARGLVGRAHQISKSDKAASRDKDYRARGRDDKARKNMQDGASDGEIPKFDGAGYDKDLVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPTAKGRAELLKISLREVELDPDIHLEDIAEKTEGYSGADITNICRDASLMAMRRRINGLSPEEIRALSKEELQMPVTRGDLELALKKIAKSVSAADLEKYEKWMVEFGSA
What is the function of this protein?
Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility.  Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity).  Has microtubule-severing activity in vitro (By similarity).
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A-like 1, Katanin p60 subunit A-like 1, p60 katanin-like 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with microtubules throughout the basal and adluminal compartments of Sertoli cells (By similarity). Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (By similarity).
Protein: DAPB_COXB1
Sequence: MAINVIINGINGKMGRVVKENITAQSDLELVSGTGRQDDLAKTIQTTHADVVIDFTTPQSVFHNAEIIIQSGARPVIGTTGLTLEQIALLDKQCRNKKLGAIVAPNFSVGAVLMMKYAKEAAHYFPDVEIIEMHHSQKIDAPSGTAIKTAQMIGEMRSSKKDEPFKDRARGEIKNGIPIHSIRLPGLFSHQSVIFGSNGETLTIRHDGMDRNCTMPGIFMACRKVMELDYLVYGLENLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP139_RAT
Sequence: MEHTHAHLAANSSACGLGFVPVVYYSFLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFILTMQMPPIPDKIIEVLEFSSIHTSIWITVPLTVDRYIAVCHPLKYHTVSYPARTRKVILSVYITCFLTSIPYYWWPNIWTEDYISTSMHHVLVWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNPWLVHIMLDVANMLALLNTAINFFLYCFISKRFRTMAAATLKALFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKHGKPIKVSP
What is the function of this protein?
Orphan receptor.  Seems to act through a G(q/11)-mediated pathway.
What are the official names of this protein?
Probable G-protein coupled receptor 139, G(q)-coupled orphan receptor GPRg1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KS6AB_XENLA
Sequence: MPLAQLVDLWPEVELVHEDTENGHGGPEDRGRHTSKDEVVVKEIPITHHVKEGAEKADQSHFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNATNRLGSGVEGAEELKRHPFFSTIDWNKLYRRELSPPFKPSVTQPDDTYYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVAPVLVEEDAKKTSSPPVLSVPKTHSKNVLFTDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKSKRDPSEEIEILRRYGQHPNIITLKDVYEECNSIYLVTELMRGGELLDRILRQKFFSEREACSVLFTVCKTVEYLHSQGVVHRDLKPSNILYVDESGDPESIRICDFGFSKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPGDTPEEILARIGS
What is the function of this protein?
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of transcription.
What are the official names of this protein?
Ribosomal protein S6 kinase 2 beta, Ribosomal protein S6 kinase II beta, S6KII-beta, p90-RSK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Protein: RL5_BACTN
Sequence: MSNTASLKKEYADRIAPALKSQFQYSSTMQVPVLKKIVINQGLGMAVADKKIIEVAINEMTAITGQKAVATISRKDIANFKLRKKMPIGVMVTLRRERMYEFLEKLVRVALPRIRDFKGIESKFDGKGNYTLGIQEQIIFPEINIDSITRILGMNITFVTSAETDEEGYALLKEFGLPFKNAKKD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GATB_BACP2
Sequence: MNFETVIGLEVHVELKTQSKIFSSSPTPFGAAANTQTSVIDLGYPGVLPVLNKEAVNFAMKAAMALNCEIATDTKFDRKNYFYPDNPKAYQISQFDKPIGENGWIEIEVEGKTKRIGITRLHLEEDAGKLTHTGDGYSLVDFNRQGTPLVEIVSEPDIRTPEEAYAYLEKLKSIIQYTGVSDCKMEEGSLRCDANISLRPIGREEFGTKTELKNLNSFAFVQKGLEFEEKRQEQVLLSGGLIEQETRRYDEASKKTILMRVKEGSDDYRYFPEPDLVELYIDDEWKERVRASIPELPDERRKRYIDDLGLPAYDAMVLTLTKEMSDFFEATITEGAEAKQASNWLMGEVSAYLNSAQKELEDTKLTPQGLAGMIKLIEKGTISSKIAKKVFKELIENGGDAETIVKEKGLVQISDEGALLKLVTEALDNNPQSIEDFRNGKDRAIGFLVGQIMKASKGQANPPMVNKILLEEIKKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LEUD_ANOFW
Sequence: MEPFVVHKGKVAGLDRANIDTDQIIPKQFLKRIERTGFGQFLFYDWRYLSDGTPNPHFELNRPENEGATILVANENFGCGSSREHAPWALADYGFRAIIAPSFADIFYNNCLKNSLLPIKLPKEDVAYLLKQAERADYELTISLEQQVVFDDEGFTSSFDIDPYRKQLLLKGWDEIDLTFVYEPYIIAYEKKRS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: C98A9_ARATH
Sequence: MDLLLISLTTIIIAAYMQNLRRRGSNIPPGPPTRFLVGNLHQLKPLWTQSFSEWSQTYGPIISVWLGSQLAVVVSSSDLAKQVLRDKDYQLCNRHRTARMTQNGSDLIWSDYGAHYVKMRKLCTLELFSLKSIECFRSMREMEVSSMVKSIFNDFMSDDQKPVVLRNYLDSVALNIVSRLVIGKTFEPKDGREFRSIVERETRLPGATKMLDYTVWLKRLSSWFTSDKAFMKHMARKRNWFKRAVMDEVYGGRDQKCFVQSLLELKEKDELTEETVMGLVWNMLTAGADTTAITIEWAMAEMIRCPTVKEKVQDELDSVVGSGRLMSDADIPKLPFLQCVLKEALRLHPPTPLMLPHKASESVQVGGYKVPKGATVYVNVQAIARDPANWSNPDEFRPERFLVEETDVKGQDFRVLPFGSGRRVCPAAQLSLNMMTLALGSLLHCFSWTSSTPREHIDMTEKPGLVCYMKAPLQALASSRLPQELYL
What is the function of this protein?
Acts redundantly with CYP98A8 as tricoumaroylspermidine meta-hydroxylase.  Involved in phenolamide synthesis, but a recombinant CYP98A9 is unable to hydroxylate triferuloylspermidine.  Unable to use 5-O-(4-coumaroyl) D-quinate or 5-O-(4-coumaroyl) shikimate as substrates.
What are the official names of this protein?
Cytochrome P450 98A9, p-coumarate 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SMG_XANOM
Sequence: MKESILDVLLYLFEHYFSEDADLVRDRDSLQNGLIQAGFSPAEISKAFDWLDALSEQRPSVARPHVDGPVRIYHGQELDKLDVDCRGFLLFLEQHRILDADQRELVLDRAMALDQDELDLDDLKWVVLMVLFNQPGAEAAYAWMETQMFLDEPEPVH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: DER_LAWIP
Sequence: MLPKIALVGRPNVGKSTLFNRLIRKNRAITHDRPGVTRDRMEGLVQSIGHPSFILIDTGGVILDSHYSTINIIDELHGFEKDIFQQVQLAIEESQAICLIVNARDGLLPFDEHLALFLRKTGKPILLAVNKVDGIEKEDQIVAEFHILGLPMIAVSAEHGHNIRQLENELSLLLPNNENIKDQSTAQAALKLAIIGRPNAGKSSIINAIIGKNKLIVSNIAGTTRDSIDIPFIFNKTQYLFVDTAGIRRRTKITDPVERFSVNASIKSATKANITLYVIDATEGITAQDKRLLDLLDTRKIPFILLINKTDLIAKKQKTLLSKSFKEELQFCPHIPILMVSAVTSSGLDQIIAMAEQVYLECSTRINTGVLNRAMEEIITRHQPPVVRRIRPKFFYLTQAETSPPTFVFFVNDAEKISETYVRYLERSLRKIFNLHHAPIRIRLRSSHKKRNQ
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: DPYL1_HUMAN
Sequence: MSYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG
What is the function of this protein?
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (PubMed:25358863).  Plays a role in axon guidance (PubMed:25358863).  During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone (PubMed:25358863).  Involved in invasive growth and cell migration (PubMed:11562390).  May participate in cytokinesis (PubMed:19799413).
What are the official names of this protein?
Dihydropyrimidinase-related protein 1, DRP-1, Collapsin response mediator protein 1, CRMP-1, Inactive dihydropyrimidinase, Unc-33-like phosphoprotein 3, ULIP-3.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cell projection, growth cone. Cytoplasm, cytoskeleton. Perikaryon. Note=Associated with centrosomes and the mitotic spindle during metaphase (PubMed:11562390). Colocalizes with FLNA and tubulin in the central region of DRG neuron growth cone (By similarity). Following SEMA3A stimulation of DRG neurons, colocalizes with F-actin (By similarity).
Protein: FOLD_BARHE
Sequence: MNNIIDGKKLAEKIIMKVKAETTKLRNNYKIQPGIAVIIVGNDPASQVYVTSKSKKAEECGFFSIKHMISKETQEKELLHLIATLNSDPQIHGILVQLPLPDHINTNRITQAIAFQKDVDGFHYINIGKLAANALEDAIIPCTPAGAMMMIEQQCGQDLSGLDAVVVGRSNIVGKPMAALLTAANATVTIAHSRTRDLDDVCRSADILVTAIGRPQMIKKDWVKNGAIIIDVGINRIAAPEKGVGKTRLVGDVDFEEIKEKAAAITPVPGGVGPMTIAMLMVNTLKAAARLHNLPIPKF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SP23_TENMO
Sequence: MVASIAGEEEPAAEKSQQSPDHFQPYRPYYYPPYRGYPITYPYPYPHGYPKPYHNFQTIAKPNEGPTDQPEANSANSIEEGGVSKRLFIEPIFNLFRPRPRDPIVVNQAPPPPPVIYQAPPPPPPPPIFQQAPPTIYQQPSPTIIQQAPQPSVTKLVYSQPEPSHSVIYQTQPKTELVYLNQ
What is the function of this protein?
Structural protein of a layer within the wall of the spermatophore produced probably by cell type 4 of the bean-shaped gland (BAG).  Fixation in the spermatophore seems to require covalent cross-linking of spermatophorins.
What are the official names of this protein?
Spermatophorin SP23.
What are the subcellular locations of this protein?
Secreted.
Protein: CLRN3_RAT
Sequence: MPTTQKTLMFLSGFLTSLGSVVVICSILGTQAWITSKIFFTDTISNGTIAITYGLFRGTSSQDLNEGLQELDKNFEVLGILSNSSQKSLHVVVIILLILSLAASLLSSMFTFYNSISNPYQTFLGPMGVYTWNGLSASFVFLTMVLFVGNVDSNHLSEKLSQTLYPDAINKKTTHTYGYSFWLILLVILLNIVTVVIIIFYQKARYHQKQEQRKPVEYAPRDGILF
What are the official names of this protein?
Clarin-3, Transmembrane protein 12.
What is the protein family that this protein belongs to?
Belongs to the clarin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TOLB_FRATM
Sequence: MRKIIAGVFIFVFLISNLYADLVAEVTTGVIQKPLVTVVSDNVVDQFPQQVNFVIVADLNHNAKLQANDTIKYEIKQKQNIPWKSLKSDYVVLTKYTNNSYNNYTVEVQILKRNDTSYLQAITYKNINVSLMRALAHKISNYVYQKLTGNQGFFLTKLAYVKVSNPYARYGRLYELIISDYDGYNKHVVLRQTDNPIATPSWSNDGRYIVYSSYSGGSMGVYTLEIATGKVTRITNYKGINSSPSFSPDGKEIALALSKGYSDQTNIYIMNLSTKALKRITINGINTAPKFSPNGQSIVFTSDREGRPNIYVASVNSKYPQSSILSTKIHQAYEPNYTPDGKNIVFMNQSSRTSGTQIADFNLANGSVTNITNGKADSSPTVSPYGDMVAYISTNTRGYSSLDMVSLDGDNHFNIETADNGNILIQSPSWSPKNF
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TES_EULMM
Sequence: MDLETKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDILLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAARKNVSINTVTYEWAPPVQNQALARQYMQMLPKDKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKNEALGVGDVKLPCELDARGPNQMYIPGGDRSTSAAVGAMEDKSAEHKNTQYSCYCCKMSMKEGDPAIYAERAGYDKLWHPACFVCSICYELLVDMIYFWKDEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: Y243_CORGL
Sequence: MTQPDMSQILAQAQQMQAQLQAAQQEILATTVVGNAGNGLVTVTMAGNGEVSAVTVDPKVVDPEDVETLQDLLLGAFKDAHNKVANVAEEKMGPLSQGMGGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Cgl0243/cg0297.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GLPK_BACC4
Sequence: MKKYILSLDQGTTSSRAILFNKKGEIVHSAQKEFTQHFPKPGWVEHNAQEIWGSILAVIATCLSEADVKPEQIAGIGITNQRETTVVWDKTTSKPIYNAIVWQSRQTAEICDELKEKGYSEMVREKTGLLIDAYFSGTKVKWILDNVEGAREKAENGDLLFGTIDSWLVWKLSGGKAHVTDYSNASRTLMFNIHDLQWDDELLEMLTVPKSMLPEVRPSSEIYGETIDYHFFGQNVPIAGVAGDQQAALFGQACFGEGMAKNTYGTGCFMLMNTGEKAVASEHGLLTTIAWGIDGKVNYALEGSIFVAGSAIQWLRDGMRMFKDASESEVYASRVESTDGVYVVPAFVGLGTPYWDSEVRGAMFGVTRGTTKEHFIRATLESLAYQTKDVLCAMEADSGIELKTLRVDGGAVKNNFLMKFQSDILDVPVERPVINETTALGAAYLAGLAVGYWKNQDEIKEQWHMDKRFEPTMEAKTSEELYAGWKKAIEATKAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.