PharMolix/UniProtQA huggingface dataset:
Protein: Y1461_METM6
Sequence: MKEVGIVGYGSDLPKYRIKAEDIAGAWGKDAQAIKRGLIVNEKSVPGPDEDTATISVQAARRALSRAGINPKDIGAVYVGSESHPYAVKPTSGIVAEACGVSPDFTAADLEFACKAGTAGIQMCMGLVGSGMMEYAMAVGADTAQGAPGDALEYTAAAGGAAYIIGAKKEELIAKFNGTYSYTTDTPDFWRREHEHYPKHGGRFTGEPAYFKHVLNGAKGMMAKMDTTAKDYDYCVFHQPNGKFYITAAKQLGFTEEQYKYGLLTPYLGNTYSGAVPLGLSNILDHAKADDRIFVVSYGSGAGSDAFDITVTDRISEVVDKEITTEKLLESKKYVDYAVYLKYRGKIRM
What are the official names of this protein?
UPF0219 protein MmarC6_1461.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. UPF0219 family.
Protein: CLPX_LEPCP
Sequence: MPEKKGSSGEKILYCSFCGKSQHEVKKLIAGPSVFICDECIELCNDIIRDEVPAVEAGGKTSRSDLPVPSEIKTLLDQYVIGQDAAKRTLSVAVYNHYKRLKHMADKGKGEEVELAKSNILLIGPTGSGKTLLAQTLARMLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVERAQRGIVYIDEIDKISRKADNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFLQIDTTNILFICGGAFDGLEKVIANRSEKSGIGFGATVKSKAERSVSEVFRQIEPEDLIKFGIIPELVGRLPVIATLGELTEDALVQILTEPKNALLKQYQRLFGMDGVELEIRPSGLAAIAQKALKRKTGARGLRSIVEQALMDTMFELPAMDGVAKVVVDENTIEDNTMPLLVYREQAKASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: DTD_POLNA
Sequence: MKAVLQRVAEARVVVAGETVGRIGQGLLVLVCAERGDSEAQADKLLAKILKLRIFSDDAGKMNRSVQDLDGQGACGGLLVVSQFTLAADASGGNRPSFTGAAPPDVGRRLYDYFVAQARKLHPQVETGQFAADMQVHLVNDGPVTIPLHIAPDA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VLN1_ORYSI
Sequence: MKGVDDAFLGVGDKPGLDIWCIMGSNLIAIEKSLHGKFYTGNTYIILSTVELKSGVRQHNVHYWVGEEAKEEDCLTASDKAIELDVALGSNTVQYRETQGEESDKFLSYFKPCIIPIQGSLSSHMRIYGDKSKDTTMFRCEGEHVARVTEVPFSRSSLDHKAVFVVDTESKIFLFSGCNSSMQTRAKALDVVKHLKENRHCGRCEIATIEDGKLVGDSDAGDFWNLFGGYAPIPRDVQDTVMTELMTTSSKKLFWINKRNLVPVETNLLEREMLNSDRNYILDCGTEVFLWMGMTTLVSERRTSVTALEDYVRCEGRQSNARSVILTEGHETVEFKMHFQHWPKNAVPKLYEAGREKVAAIFKHQGYDVTEIPEDKPRHFISCNGSLKVWLVDNGSVTLLCTEEQEQLYNGDCYIIRYSYIEDGKDYHLFFAWSGLNSINEDRVAAASLMSGMIDSVKGHAVVAQVFEGREPEMFFLVFKSLIIFKGGRSMAYKNFVSQRSDANGWYQKNGVALFRVQGLKHDCIRAIQVDLAASSLNSSHCYILQAGGSFFTWLGSLSSPSDHNLLDRMMDKLCPLKQSLLVREGSEPDRFWEALGGRSEYSKEKQVKDWPADPHLYTCHFEQGLFKAKEVFSFSQDDLVTEEILILDCVEELHIWVGHQSGVLSMEQALDIGKMFLQAGIHQDGRRPIDTTMYIVTEGDEPRFFTSFFNWDYSKQTMLGNSFERKLAILKGISQKLETPERSLRKSSSSSLPRRSPGTSSSEPTTPEQRAAARTFASASTGKLLRERSPAALSPSLSTPSPSPRSRSSASSSPASWNSTPSTVARRLFPPSLHASAEAVATGTPRRL
What is the function of this protein?
Ca(2+)-independent actin-binding protein.  Binds actin microfilaments (MFs).  Involved in actin filament bundling, severing and capping.  Caps the barbed end of actin filaments and protects them from disassembly.  Promotes VLN3-mediated MF severing.
What are the official names of this protein?
Villin-1.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AROL_SHIF8
Sequence: MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_DICTD
Sequence: MIIKRSRKELRRIRHLRIRKKITGTPERPRLAVYKSLRYIYAQIIDDTKGHTLVAASSLEKELRSQLKSTKNIEAAKLVGEVIAKRALEKGIKRVVFDRGGFLYHGKVKALADSARAAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PP4CA_DANRE
Sequence: MCVIMGDFTDLDRQIEQLRRCELIKENEVKALCAKAREILVEESNVQSVDSPVTVCGDIHGQFYDLKELFRVGGEVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFFDECHRKYGSATVWRYCTEIFDYLSLSAIVDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDISMICRAHQLVMEGYKWHFNDTVLTVWSAPNYCYRCGNVAAILELDEHLQKEFIIFEAAPQETRGLPSKKPVADYFL
What is the function of this protein?
Protein phosphatase that regulates many processes such as microtubule organization at centrosomes.
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 catalytic subunit A, PP4C-A.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: GP182_MOUSE
Sequence: MSVIPSPRPVSTLEPDNDFRDIHNWTELLHLFNQTFTDCHIEFNENTKHVVLFVFYLAIFVVGLVENVLVICVNCRRSGRVGMLNLYILNMAIADLGIILSLPVWMLEVMLEYTWLWGSFSCRFIHYFYLVNMYSSIFFLTCLSIDRYVTLTNTSPSWQRHQHRIRRAVCAGVWVLSAIIPLPEVVHIQLLDGSEPMCLFLAPFETYSAWALAVALSATILGFLLPFLLIAVFNILTACRLRRQRQTESRRHCLLMWAYIVVFAICWLPYQVTMLLLTLHGTHIFLHCHLVNLLYFFYEIIDCFSMLHCVANPILYNFLSPSFRGRLLSLVVRYLPKEQARAAGGRASSSSSTQHSIIITKEGSLPLQRISTPTPSETFRRPLRLQTPHLHSAIL
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
G-protein coupled receptor 182, G10D, NOW.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KCY_HALMA
Sequence: MLITVSGPAGSGKSTLAKSLADALNYEHVSGGDIFRSLAEERGMTPLELNKAAEEDDQIDRDLDRKLRDIAAERDDLVLESRLAGWMAGEYADMKLWLTAPLDVRADRIATRENKPFEQAKTETRERGDSEAQRYSDYYDIDFDDLSIYDLSVNTARWDPQGVLSVTLHAVESYSPDGDEGKAPVENIRYEF
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIO_AILME
Sequence: MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGPGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGTHGQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGSDYEDRYYRENMHRYPNQVYYRPVDQYSNQNNFVHDCVNITVKEHTVTTTTKGENFTETDIKMMERVVEQMCITQYQRESQAYYQRGASVILFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: ATRGA_MALDO
Sequence: MMSFSVLQVKRLQPELITPAKSTPQETKFLSDIDDQESLRVQIPIIMCYKDNPSLNKNRNPVKAIREALSRALVYYYPLAGRLREGPNRKLVVDCNGEGILFVEASADVTLEQLGDKILPPCPLLEEFLYNFPGSDGIIDCPLLLIQVTCLTCGGFILALRLNHTMCDAAGLLLFLTAIAEMARGAHAPSILPVWERELLFARDPPRITCAHHEYEDVIGHSDGSYASSNQSNMVQRSFYFGAKEMRVLRKQIPPHLISTCSTFDLITACLWKCRTLALNINPKEAVRVSCIVNARGKHNNVRLPLGYYGNAFAFPAAISKAEPLCKNPLGYALELVKKAKATMNEEYLRSVADLLVLRGRPQYSSTGSYLIVSDNTRVGFGDVNFGWGQPVFAGPVKALDLISFYVQHKNNTEDGILVPMCLPSSAMERFQQELERITQEPKEDICNNLRSTSQ
What is the function of this protein?
Involved in the biosynthesis of volatile esters which confer ripe apple fruit flavor (PubMed:24661745, Ref. 3).  Alcohol acyl transferase that can use a wide range of alcohols as substrate, including 2-methylbutanol, hexanol and ethanol, to produce esters such as butyl butanoate, butyl hexanoate, hexyl butanoate, 2-methylbutyl acetate (2MBA), butyl acetate, hexyl acetate and 2-methylbutyl butanoate (2MBB), and, to some extent, ethyl butanoate and ethyl hexanoate (PubMed:24661745, PubMed:15955071).
What are the official names of this protein?
Alcohol acyl transferase 1 allele RGa, AAT1-RGa, MpAAT1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: RUVC_PROA2
Sequence: MIVLGVDPGSVHTGYGVVLCNGQKFSLVACGLIRLSSNQSIADRIKIIYDELGAIIAEYNPQRLALETAYVNRNPQSALKLGQVRGAIVALTMNKGLELHEYAPREVKYVLTGKGSAGKEQVSYMARHFLNIQEPIKPYDVTDALGIALCDLLCDAKGGSPRRGSGSRKSARGGWEDFVRTNPELIV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: Y4EA_SINFN
Sequence: MPRPGGSYSTSDLSRKSGDIIAEALRHPVTITQRNKPRLVLLNIDDYERLMRQYDARSVGTLETLPGELLNEFEAAVDAYGETDETNR
What are the official names of this protein?
Uncharacterized protein y4eA.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: RL25_YERPG
Sequence: MTTINVEVRNDQGKGASRRLRAANKFPAIVYGGSEAAISIALDHDTTKNLELKPGFYDSVLTLVIDGKETKVKVQAVQRHAFKPKLTHIDFVRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: FEX1_YEAST
Sequence: MIFNPVISNHKLSHYIHVFCTFTTFCILGTETRQAITALSTYTPAFVTAPTVLWSNCSSCMLMGIMQSLNAYTWMKDHQVLFLGVTTGYCGALSSFSSMLLEMFEHSTNLTNGNIANHTKLPNRAYGIMEFLSVLLVHLMVSMGSLIFGRQLGKEVIVAYGSSSFSKPYTPPSDTVKENAGDVDTQEMEKNILEFKFKTPAPFFKKFFDIVDKLAYALAFPLIILFVVLCAYYENYSRGKWTLPCLFGIFAGFLRYWLAEMFNKTNKKFPLGTFLANVFATLLIGIFTMVQRGKKHFSTDVPIVNSLNSCHIVSALISGFCGTLSTISTFINEGYKLSFINMLIYYTVSIAISYCLLVITLGSYAWTRGLTNPIC
What is the function of this protein?
Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
What are the official names of this protein?
Fluoride export protein 1.
What is the protein family that this protein belongs to?
Belongs to the fluoride exporter Fluc/FEX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VPB15_ARCFU
Sequence: MPTKTITITLEAYERLKREKREGESFSDVIIRLTEKRRDLLEFAGKWKDSGEEIEKIILEGRKEFDKHVLS
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC15 (Potential).
What are the official names of this protein?
Putative antitoxin VapB15.
What is the protein family that this protein belongs to?
Belongs to the UPF0330 family.
Protein: BIKB_THET8
Sequence: MSLDLRARVREELERLKREGLYISPKVLEAPQEPVTRVEGREVVNLASNNYLGFANHPYLKEKARQYLEKWGAGSGAVRTIAGTFTYHVELEEALARFKGTESALVLQSGFTANQGVLGALLKEGDVVFSDELNHASIIDGLRLTKATRLVFRHADVAHLEELLKAHDTDGLKLIVTDGVFSMDGDIAPLDKIVPLAKKYKAVVYVDDAHGSGVLGEKGKGTVHHFGFHQDPDVVQVATLSKAWAGIGGYAAGARELKDLLINKARPFLFSTSHPPAVVGALLGALELIEKEPERVERLWENTRYFKRELARLGYDTLGSQTPITPVLFGEAPLAFEASRLLLEEGVFAVGIGFPTVPRGKARIRNIVTAAHTKEMLDKALEAYEKVGKRLGIIR
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide (By similarity).  Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate.  It also converts 2-amino-3-ketobutyrate and CoA to glycine and acetyl-CoA.  Activity is also observed with the following combinations of substrates: acetyl-CoA and either L-alanine or L-serine, pimeloyl-CoA and either glycine or L-serine, and palmitoyl-CoA with L-alanine.
What are the official names of this protein?
8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase, AONS/AKB ligase, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase, Glycine acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: TRPA_VIBCM
Sequence: MNRYQALFQRLSAAQQGAFVPFVTIGDPNPEQSLAIMQTLIDAGADALELGMPFSDPLADGPTIQGANLRALAAKTTPDICFELIAQIRARNPETPIGLLMYANLVYARGIDDFYQRCQKAGVDSVLIADVPTNESQPFVAAAEKFGIQPIFIAPPTASDETLRAVAQLGKGYTYLLSRAGVTGAETKANMPVHALLERLQQFDAPPALLGFGISEPAQVKQAIEAGAAGAISGSAVVKIIETHLDNPAKQLTELANFTQAMKKATKI
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: NRDR_VIBA3
Sequence: MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREPFNEDKMVGGVQRALEKRPVSADAIELAISTIKSQLRATGEREVPSEMIGNLVMGQLKELDKVAYIRFASVYRSFEDIREFGEEIAKLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MOAC_THEAC
Sequence: MINISEKAISARTATATGRIHLRRSTIQAIREKKVKKGDVLEVSRVVGTQHAKNTFLQIPYCHNIPIEGVDVDFNVGEDYVEVSCTLTTTYKTGIEMEAISCVSGALINIWDMVKYLEKDESGNYPETRIDGIHVVEKRKTPV
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Probable cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: MTNN_ERWT9
Sequence: MKAGIIGAMEQEVTLLRDKIENRQTLTLAGCEIYTGTLNGVDVALLKSGIGKVSAALGTTLLLELCKPDVVINTGSAGGLAATLKVGDIVVSDEVRYHDADVTAFGYEAGQMAGCPAAFKADEKLITAVEQCIHQLDLHAVRGLVVSGDAFINGAAPLAHIRNTFPQAIAVEMEATAIGHVCHQFGTPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLLVEKLLAHLAQG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: NUOH1_RHOPA
Sequence: MAEFFATNLWPLLVVIGQSVLLLVILLIAIAYILLADRKIWAAVQIRRGPNVVGPWGLLQSFADLLKFVLKEPTIPDGANKGLFLLAPLVTCVLALAAWAVIPVNAGWVIADINVGVLYILAVSSLSVYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSIGFVVICVLLCVGSLNLTAIVEAQDGKWGMLGWYWLPLFPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYSSTPYLLFMLGEYVAIVTMCAMGTILFLGGWLPPVPYAPFTWVPGIVWFSLKLLFMFFLFAMAKAIVPRYRYDQLMRLGWKVFLPLSLAMVVIVASVLQFADLAPK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 1, NADH dehydrogenase I subunit H 1, NDH-1 subunit H 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INSL6_DROME
Sequence: MVLKVPTSKVLLVLATLFAVAAMISSWMPQVAASPLAPTEYEQRRMMCSTGLSDVIQKICVSGTVALGDVFPNSFGKRRKRDLQNVTDLCCKSGGCTYRELLQYCKG
What are the official names of this protein?
Probable insulin-like peptide 6, dILP6, Insulin-related peptide 6.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: UAY_EMENI
Sequence: MLNPSTSDIHTSPTAVGNGRKRPHPIADSGSAMPSDPSAQQLPHPANESAAIPSIASSSSFRNVSACNRCRQRKNRCDQRLPRCQACEKAGVRCVGYDPITKREIPRSYVYFLESRVAYLEKVLMDNGIEYNEAVAFDEEEAVKIEAGYEAYAGSANGPAAGEIAAQDGSNDKSVRIKKEKNGPLGLEKASRYDHDPEVKQDSDAEDGWRIQNLVSNIGMVSVQGTSDPRYLGSTSGISFARVVFAAVKSSVPGNSSERGPSRPKERLPHSATGTEGSTTRDSFFGLQTRPMMKCAAFPDRELAERLADLYFEHANPQIPIVHRVDFMELLDRTYSVDEKSRSPRSLYFLNIVFAIGSGIIFEDKPAEDQKEGRDHSPSATKRQRLSSRQYQPEEYHASAIVHLESFLSTSPTTDGFGALEELQAVLLLASFALLRPVAPGLWYIVGVAMRLAVDLGLHYEDGAGIDGPENDNMNRTNNKDGEKAKLRIDDHERGRREWVRDFRRRLWWCCYSFDRLVSCCVGRPFGISDQAISTEFPSILEDKYITKSGIIKAPEGAPSYKHSAFHYFKLRVLQSEIQDVLQHQQARFARQRGPPGARSFMRLDVVSPFLQGFDSFRSWRRDVDRRLLEWKNSAPMPSENGVRFPLEFLELNYWQAVIMLYQQSLTVPAELADELSPAEDVSSPSFSQVEEDEHDIYYKVAEAGQKVIRIYRQMHRVRLVNYTYLATHHIFMAGISFLYAIWHSPYVRSRLTLDEVDFTVLAATSVLRDLMHKCPPAEACRDAFERMSKATVEMSLSTTGFGPQVELNRVQTSTSGSRQFNATQSRSRPYSRQQAEQRQRQSASRRQLQMRQSRPLPRFDMNLEDLFGDNRAVAERQGSGGMGKLAQPYPVSETSDPNFARPQSHRNPSMEYYGPFENPVSPQQPQPQPRYYYNNSPQQSGSPGSVVAASGIPPYQVTPTEQENPSGMGLDYLDYDPTGIERQLSLGSEENSDFKFQGGAQSLGHGAGHNFGIDLGFGMAVDFQHDWSENANYDLLEGYFFGGAGATGPGHGHGHGSGI
What is the function of this protein?
Mediates the induction of a number of unlinked genes involved in purine utilization.  Binds to the consensus sequence 5'-TCGGNNNNNNCCGA-3'.
What are the official names of this protein?
Positive regulator of purine utilization.
What are the subcellular locations of this protein?
Nucleus.
Protein: THTM_MOUSE
Sequence: MAAPQLFRALVSAQWVAEALKAPRSSQPLKLLDASWYLPKLGRDARREFEERHIPGAAFFDIDRCSDHTSPYDHMLPNATHFADYAGSLGVSAATHVVIYDDSDQGLYSAPRVWWMFRAFGHHSVSLLDGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDARRFQVVDARAAGRFQGTQPEPRDGIEPGHIPGSVNIPFTEFLTNEGLEKSPEEIKRLFKEKKVDLSKPLVATCGSGVTACHVVLGAFLCGKSDVPVYDGSWVEWYMRAQPEHIISEGRGKTQ
What is the function of this protein?
Transfer of a sulfur ion to cyanide or to other thiol compounds.  Also has weak rhodanese activity.  Detoxifies cyanide and is required for thiosulfate biosynthesis.  Acts as an antioxidant.  In combination with cysteine aminotransferase (CAT), contributes to the catabolism of cysteine and is an important producer of hydrogen sulfide in the brain, retina and vascular endothelial cells.  Hydrogen sulfide H(2)S is an important synaptic modulator, signaling molecule, smooth muscle contractor and neuroprotectant.  Its production by the 3MST/CAT pathway is regulated by calcium ions.
What are the official names of this protein?
3-mercaptopyruvate sulfurtransferase, MST.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Synapse, synaptosome.
Protein: BBX18_ARATH
Sequence: MRILCDACESAAAIVFCAADEAALCCSCDEKVHKCNKLASRHLRVGLADPSNAPSCDICENAPAFFYCEIDGSSLCLQCDMVVHVGGKRTHRRFLLLRQRIEFPGDKPNHADQLGLRCQKASSGRGQESNGNGDHDHNMIDLNSNPQRVHEPGSHNQEEGIDVNNANNHEHE
What is the function of this protein?
Acts as negative regulator of seedling photomorphogenesis (PubMed:18540109).  Acts as a negative regulator of blue light-mediated inhibition of hypocotyl elongation through increase of bioactive gibberellin levels (PubMed:20872270).  Acts as a repressor of thermotolerance by modulating expression of a set of heat shock-responsive genes (PubMed:23238922).
What are the official names of this protein?
B-box zinc finger protein 18, Protein DOUBLE B-BOX 1A, Protein SALT TOLERANCE HOMOLOG 4.
Protein: ADDH_SCHPO
Sequence: MLSKKFTPLSLKNAAKCINNSLRSTYAITGVNLTRGLATNSKVDPKTYAPKPEFSSIAVREMLRKSCLHEFTDEEVATRIELAAAYRLFGLEHWNENILNHLTAKVEEPDGTASFLINPYGLRYGEITASSLIKVDEDGNIKHPGVTGDVFGINRAGYVIHSAIHRARPDVKSIMHNHYPYAAGVSCVKHGFLELAQTSHQSGPVTYHDYHGIVVDKGEQKSLAEDIANKDILILRNHGIITAAESVGAAYYLMYQFLAATEIQTHASANALGDMNNLFIPNNKLVEKTFDVTREKHFSGAKYGIKELSAYMRLLDDLDSSYRT
What are the official names of this protein?
Adducin-related protein C1289.14.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. Adducin subfamily.
Protein: VAP21_ARATH
Sequence: MTGVGENQLISIQPDELKFLFELEKQSYCDLKVANKTENYVAFKVKTTSPKKYFVRPNTGVIQPWDSCIIRVTLQAQREYPPDMQCKDKFLLQSTIVPPHTDVDELPQDTFTKDSGKTLTECKLKVSYITPSTTQRSSESGATNGDGQSSETISTIQRLKEERDAAVKQTQQLQHELETVRRRRNQRNSGNGLSLKLAAMVGLIGLIIGFILKLTLASPT
What is the function of this protein?
May play a role in vesicle trafficking.
What are the official names of this protein?
Vesicle-associated protein 2-1, Plant VAP homolog 21, AtPVA21, VAMP-associated protein 2-1.
What is the protein family that this protein belongs to?
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side.