PharMolix/UniProtQA huggingface dataset:
Protein: O51B6_HUMAN
Sequence: MGLNKSASTFQLTGFPGMEKAHHWIFIPLLAAYISILLGNGTLLFLIRNDHNLHEPMYYFLAMLAATDLGVTLTTMPTVLGVLWLDHREIGHGACFSQAYFIHTLSVMESGVLLAMAYDCFITIRSPLRYTSILTNTQVMKIGVRVLTRAGLSIMPIVVRLHWFPYCRSHVLSHAFCLHQDVIKLACADITFNRLYPVVVLFAMVLLDFLIIFFSYILILKTVMGIGSGGERAKALNTCVSHICCILVFYVTVVCLTFIHRFGKHVPHVVHITMSYIHFLFPPFMNPFIYSIKTKQIQSGILRLFSLPHSRA
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 51B6, Odorant receptor HOR5'beta6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RASK_MELGA
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKTKTKCIIM
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.  Plays an important role in the regulation of cell proliferation.  May play a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs).
What are the official names of this protein?
GTPase KRas, K-Ras 2, Ki-Ras, K-ras.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm.
Protein: SYT_SALNS
Sequence: MPVITLPDGSQRHYDHPVSPMDVALDIGPGLAKATIAGRVNGELVDASDLIENDATLAIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVVDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHDARETFVKRGETYKVAILDENIAHDDKPGLYHHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHIFCTEEQIRDEVNACIRMVYDMYSTFGFEKIVVKLSTRPDKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVVMNITDSQSEYVNELTQKLQNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVEAGKVAVRTRRGKDLGSLDVNDVIEKLQQEIRSRSLQQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_NEIG2
Sequence: MKLSELFNPNEFAARHLSFGDEAALLAAVGEKSMDDFVGNTLPQSIRMPSELDLPEALTEADALAKLKGIASKNVINKSYIGLGYYPTRVPNVILRNVLENPGWYTAYTPYQAEIAQGRLEALLNFQQVCIDLTGFPVAGASLLDEATAAAEAMAMAHRVGKVKSERFFVDARVYPQTLDVMKTRAKYFGFELVVSDFAQADEGEYFGALFQYVGKDGDVQDLQDVIGRLKAKGTIVAVAADIMSLVLLKSPAELGADIALGNTQRFGVPMGFGGPHAAYFAFKDEFKRSAPGRIIGVSKDASGKPALRMALSTREQHIRREKATSNICTAQALLTNLAGMYAVYHGPKGVKRIANRIHTLASVFADALVSDGLKVVHEVFFDTVTVDFGSKEKADQVFAAALESGYNLRRVNNTQVAAAFHETSVYEDLADLYRAFTGKDTFTFADDVKGRLNAELLRQDDILQHPVYNSYHTEHEMLRYLKKLEDRDLAMNRSMISLGSCTMKLNATAEMLPITWTEFSDIHPYAPEAQTAGYRELLADMENSLKAITGFDAISFQPNSGAQGEYSGMLAIRRYQEAQGEAHRNICLIPKSAHGTNPATAAMLGLKVVVVDTDEHGNVNIDDLKAKAEQHRDALSAIMITYPSTHGVYEEGIRDICRIIHENGGQVYMDGANLNAQIGIMQPAEVGADVLHMNLHKTFCIPHGGGGPGMGPIGLKAHLAPFAPGHTLTDTHSASAGQTSVAAAAFGSASILPITWMYLTMMGKQGMEQATRWALLNANYVAKRLSEDYPILYTGKNGRIAHECIVDLRPLKAESGITETDIAKRLMDYGFHAPTVSFPVAGTLMIEPTESESKAELDRFIAALKSIRREVQKVIDGEWPKDDNPLVNAPHTAADITGEWAHPYSREEAVFPLPFVREHKFWPFVNRVDDVYGDRNLVCSCPPMENYED
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: PPAC_BACMK
Sequence: MEKVLVFGHKNPDTDAICSAIAYAELKKELGMNAEPVRLGEISGETQFALDSFKVEGPRFVETVANEVDNVILVDHNERQQSANDIESVRVLEVIDHHRIANFETSDPIYYRCEPVGCTATILNKMYKENGVTIRKEVAGLMLSAIISDSLLFKSPTCTEQDVAAARELAEIAGVDADSYGLEMLKAGADLSGKTMEQLISLDAKEFQMGNAKVEIAQVNAVDTNDVLVHQAELEKVITTVVEEKGLDLFLFVVTDILTNDSVGLAIGKATNVVEKAYNVTLQNNTATLKGVVSRKKQIVPVLTETFQA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTM_APLCA
Sequence: MCDDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVPPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLSKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPILLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKEITSLAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
What are the official names of this protein?
Actin, muscle.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ERA_STRPC
Sequence: MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTLIKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNEKEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: TMM33_RAT
Sequence: MADTTPNGPQGAGAVQFMMTNKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDAKGSNSLPLLRSVLDKLSTNQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRNLFNELRIVVEHIIMKPSCPLFVRRLCLQSIAFISRLAPTVA
What is the function of this protein?
Acts as a regulator of the tubular endoplasmic reticulum (ER) network by modulating intracellular calcium homeostasis.  Mechanistically, stimulates PKD2 calcium-dependent activity (By similarity).  Suppresses the RTN3/4-induced formation of the ER tubules.  Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling.  Plays an essential role in VEGF-mediated release of Ca(2+) from ER stores during angiogenesis.  Also plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26.  Participates in lipid metabolism by acting as a downstream effector of the pyruvate kinase/PKM.  Forms a complex with RNF5 to facilitate polyubiquitination and subsequent degradation of SCAP on the ER membrane (By similarity).
What are the official names of this protein?
Transmembrane protein 33, Protein DB83.
What is the protein family that this protein belongs to?
Belongs to the PER33/POM33 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Melanosome. Nucleus envelope. Note=Co-localizes with RTN4 at the ER sheets.
Protein: RNPA_SHESW
Sequence: MTSYTFTRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNSEQHPRLGLTVAKRYVKRANQRNRIKRIIRDSFRLNQHDIPHLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: LHS1_YEAST
Sequence: MRNVLRLLFLTAFVAIGSLAAVLGVDYGQQNIKAIVVSPQAPLELVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSAVGSLATRFPQNTLLHLKPLLGKSLEDETTVTLYSKQHPGLEMVSTNRSTIAFLVDNVEYPLEELVAMNVQEIANRANSLLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVSEGMSVAVNFVLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQPVTIEFEGYGYNPHLGGAKFTMDIGSLIENKFLETHPAIRTDELHANPKALAKINQAAEKAKLILSANSEASINIESLINDIDFRTSITRQEFEEFIADSLLDIVKPINDAVTKQFGGYGTNLPEINGVILAGGSSRIPIVQDQLIKLVSEEKVLRNVNADESAVNGVVMRGIKLSNSFKTKPLNVVDRSVNTYSFKLSNESELYDVFTRGSAYPNKTSILTNTTDSIPNNFTIDLFENGKLFETITVNSGAIKNSYSSDKCSSGVAYNITFDLSSDRLFSIQEVNCICQSENDIGNSKQIKNKGSRLAFTSEDVEIKRLSPSERSRLHEHIKLLDKQDKERFQFQENLNVLESNLYDARNLLMDDEVMQNGPKSQVEELSEMVKVYLDWLEDASFDTDPEDIVSRIREIGILKKKIELYMDSAKEPLNSQQFKGMLEEGHKLLQAIETHKNTVEEFLSQFETEFADTIDNVREEFKKIKQPAYVSKALSTWEETLTSFKNSISEIEKFLAKNLFGEDLREHLFEIKLQFDMYRTKLEEKLRLIKSGDESRLNEIKKLHLRNFRLQKRKEEKLKRKLEQEKSRNNNETESTVINSADDKTTIVNDKTTESNPSSEEDILHDEL
What is the function of this protein?
Chaperone required for protein translocation and folding in the endoplasmic reticulum.
What are the official names of this protein?
Heat shock protein 70 homolog LHS1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: Y2330_ARCFU
Sequence: MRWQEFEGEVRRICEAHDFSTKFRFVFKDEEGRAEIDVVAERYGIVLCFDAKLYSASRYRASQLRREAEKHRRRCERFSALTGKRAIPVVVSLIDDSLRFHSGCIIVPYHSLNEFLTNLHFYLAEFGFL
What are the official names of this protein?
Uncharacterized protein AF_2330.
Protein: RPOB_CUPTR
Sequence: MAYSFTEKKRIRKSFAKRATVHQVPFLLATQIESYTQFLQADTPPARRKTEGLQAAFNAIFPISSHNGLARMEFVSYHLSNPPFDVKECQQRGLTFHSALRAKVRLIINDRENPGKVKEVKEQEVYMGEIPLMTSTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKSIGLTPEQILAHFFVFDNFTLQSEGAQLEFVPERLRGEVARFDIADKNGRVVVEKDKRINAKHIRDLDSAGTKLISVPEDYLLGRVLAKNIIDPDTGEVIANANDELTEALLENLREAGVKQIQTLYTNDLDQGPYMSQTLRVDETADQTAARIAIYRMMRPGEPPTEEAVEALFQRLFYSEESYDLSRVGRMKVNSRLGRPSGEGAMVLQDEDILETIKILVNLRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLSRVERAVKERLGQAETENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFLETPYRKVVDSKLTDEVDYLSAIEEGKYVVAQANATVDADGNLTDELVSAREGSERETRMVTPDRVQYIDVAPSQIVSAAASLVPFLEHDDANRALMGANMQRQAVPCLRPDKPLVGTGIERTVAVDSGTAVQAMRGGVVDYVDAMRIVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPMVKVGDHVARGDVIADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAEAQLARLDESGITYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGIVIDVQVFTREGVTRDKRAQSIIDDELKRYRLDLNDQLRIVEGDAFQRLERLLVDKTVNGGPKKLAKGAKITKEYLADIDKYHWFDIRPADEELAAQLEAVKEAIEQKRHEFDLAFEEKRKKLTQGDELPPGVIKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGTPADIVLNPLGVPSRMNVGQILETHLGWAARGLGQRIGDMLKAQAKAQELRTLLSQIYNESGKPEDLDSLSDAEVLELANNLKKGVPFATPVFDGAHEDEIRRMLDLAYPDDVAREKGLTASKQQVTLFDGRTGEAFERPVTLGVMHMLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGEHSIDAGMPESFNVLVKEIRSLGIDIDLDRY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: FES_YEREN
Sequence: MKSRGLSVSTTNEHPDSQRLLADPLAGSESWWQQIAQWGTPLVEPISEDKVRLTFLWREPVAGADEPTYSRVYIDVNGVTDHHSTHPETLQRLGQTHVWYWQAEVESDFRGSYSFMPVTAEHCLNLPEGTPQERRQAQRNWWISLMDLAQNDPFNHTAPHSSYRGRPLSAVHLADAIPQTAWQPIDAGQQLPTDTQRLQLITWHSELLGNSRNVWIYHTHGTEDNAERPLAILLDGQYWATRQPIFGVLDNETDAGRLPASVYVLIDIIDQPHRSVELPCNQDFWQALQTELLPQVAALQPFTDQASRTVVAGQSFGWVGLAICRITLAAAFWWCAESSPVPSGGRMLIISKL
What is the function of this protein?
Catalyzes the hydrolysis of ferric enterobactin (Fe-Ent).  Is responsible for the release of iron from ferric enterobactin.
What are the official names of this protein?
Iron(III) enterobactin esterase, Enterochelin esterase, Ferric enterobactin esterase.
What is the protein family that this protein belongs to?
Belongs to the Fes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_DESAH
Sequence: MKTQKRETNPIVTAIESIAEPLCIAEGFELVHVECVSDQGGMIVRIYLDKPGGITLDDCVHMTRHLGDIIDVELEEISAYRLEISSPGAKRPLKKLADFERFLGSRVKVEAVEPIGGRLKFTGILSKVQDGCVEVVVNNEPVVFHFEQISKSRLA
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_NEIM0
Sequence: MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAAAAGVPIPTIFEMEGEQGFRSRETAILKKLVILPHIVLSTGGGAVLKEENRALIRKSGTVVYLHAPPETLLERTRCDNSRPLLQVADPLAKLRELYAARDPVYRQTADFTVESANCRETVQTLLKRLSR
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_PHOV8
Sequence: MKIQVINKSKHALPEYATGQSAGMDIRANLDEPIVLKPLQRCLVPTGLYIALPEGFEAQIRPRSGLAIKKGIGVLNSPGTIDADYRGEICIILVNLSSEDFMIEDGERIAQMVVARHEHAEWQEVEVLDETERGAGGFGHTGKK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: ISPH_PSEPK
Sequence: MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRNRGAIFVEELDQVPDDVIVIFSAHGVSQAVRQEAAGRGLKVFDATCPLVTKVHIEVAKYSRDGRECILIGHEGHPEVEGTMGQYDASNGGAIYLVEDEEDVANLQVRDPDHLAFVTQTTLSMDDTSRVIDALRARFPNIGGPRKDDICYATQNRQDAVKQLAGESDVVLVVGSPNSSNSNRLRELAERMGTPAYLIDGAEDLQRGWFDQAARIGITAGASAPEVLVRGVIEQLKAWGATGAEELDGREENITFSMPKELRVRSLI
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PSA_METB6
Sequence: MQPQYQMGYDRAITVFSPDGRLYQVEYAREAVKRGTTAVGIKAHDGVVLIVDKRVSSKLLESSSIEKIFKIDEHIGVASSGLVGDARALVDRARIECQINRVSYDERIEVEALAKKLCDHMQTLTQYGGIRPYGTALLIAGVSDGESRLFETDPSGTLLEYKATGIGIGRPAAMKVFEEEYTADLALKDAILLGLKALHSATEGKFDVDTVEMGIVESSTAQFKKMTKEEVASYVGQFKQ
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y527_MYCPN
Sequence: MNGARIAFWPKKEQHQLFNLSFSAMMLALALIASFVSHFISIPFLSALKLTIDISSVFLIACAFFVSYSWALVITVALSLCSFIWDGNNWIGILTLTIANFAIVSFTRLYFHIFAQIKLRWLWVFSLATLSNTLLLTTLNGLLITPLYWYWFGYVPTANFVEVAKIYNKTPYFHFFLFGVPNYWGGIFALYSLFNVIKFTLVSLIGVPVMRAFQKFYWKKAQIVY
What are the official names of this protein?
Uncharacterized protein MG350.1 homolog.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHRD1_DROME
Sequence: MEQCYNRGCGQLFDPQTNNDESCRHHPGEPFFHDAYKGWSCCNKKSVDFTEFLNIKGCTLAKHSNVKPPEPEKPVKDESDKDEVIEVRAPIREALPRPPIDSPLTVIQPTVAPALKDMVFAVKTPAAQKSSDAIEVGTTCKNNGCTYSFTGNSSDFGECTYHPGVPIFHEGMKFWSCCQKRTSDFSQFMAQKGCTYGEHKWVKENDDKKVVQCRYDWHQTATNVVMAIYAKKYDYSQSVIELNPIRLHVNLVFPEQDNARFDLDLELRGIVNVSNASAHMYGTKVEIKLPKLEPGSWSNLNFPNKKLPVVKKSQVEEKKKQEESDEEFFDLDDIKAETSFRLSEMSMQSPNNLD
What is the function of this protein?
Regulates centrosome duplication and mitotic spindle dynamics (PubMed:20230755, PubMed:31907206).  Also involved in controlling the size of dendritic arbors (PubMed:24643112).  May act as co-chaperone for Hsp83 (PubMed:31907206).  During mitotic spindle assembly, regulates microtubule (MT) dynamics by binding to MTs and promoting MT polymerisation (PubMed:31907206).  Promotes the elongation and retraction of terminal branches in response to changes in body size, possibly acting downstream of the TORC2 pathway to enable proportional scaling of dendritic arbors (PubMed:24643112).
What are the official names of this protein?
Cysteine and histidine-rich domain-containing protein morgana.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=In syncytial embryos, mostly cytoplasmic during interphase, with enrichment in the perinuclear area and a weak nuclear localization. Upon nuclear envelope breakdown, localizes to the spindles and remains associated with the spindle microtubules throughout mitosis.
Protein: RIMP_THISH
Sequence: MQLKALLEPLVTRMGYQLWGMEFRVAKHSALLRLFIDSEQGITLDDCTEVSRQVSALMDVEDPIQVPYTLEVSSPGVDRPLFEAGQYARYVGEQVRVRTQWPIDGQRNFAGAIVSADEDSVTLDVDGREVRLPLEAIARGRLKGTLPPATQVEE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRHA_METVO
Sequence: MGKTVEINPTTRHEGHTKLVLKVDDDGIVEKGNYLSVTPVRGFEKFLVGKPAEFAPIAVSRFCGICPIAHATSAVEAIEDACGIVPPKDGLLLRELTGLGNKMHSHPLHEFLIAPDFIPEKDRVEYITRIQQMRKTGQYIVDTIGGEAIHAPNIKVGGMLKSITPSAVSKIYYKCKEFEKLAKEQVEYLIPIFENRTLVDGTEIPEKLGYHDFGYLATDSTYGNRENIEQKKVHEYTPYDVYEKEVAVQACQLFQEYNGRLMEVGPRARFAKFHDFKEKGAMAIHIARAYENVIHVKRAMEIIEELNVDGLTRAKDPILGDGEKLGLGVHEAARGHNTHQASIDEKGRITYYNAIVATTWNIPLIGKAVEAHYKFAEHVVRAYDPCVSCATQHDILRL
What is the function of this protein?
Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
What are the official names of this protein?
Coenzyme F420 hydrogenase subunit alpha, 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit alpha, FRH.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
Protein: RL15E_METAR
Sequence: MVKSAYSYIRDAWKNPSKTYVGELFWERLQEWRKEPTVVKIDRPTRLDRARALGYKAKQGIIVARAHVRRGGRRKSRYSRGRKSKHMGLRTLTRRTSIQRMAEVRASRKFPNMEVLNSYWVGQDGKHKWYEIILVDPHHPSIASDKNLSWITKGTHRGRAERGLTSAGKKGRGQRRKGKGTEKNYPSVQAHDRRGK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: Y1262_AQUAE
Sequence: MRRIGAITALSLPVLLSLLYSCGTGGSASKEEILSKKEHNPEPNIPLECYTDTGVVKLGKAIANPCYVCHTKALTPYENEVDDFDLQLVYDFPEEIKEMGNPWLNAIKPELTIGSVPMPSDEEIKTWIRQDNWSKAYAEKGKGELVYFPDIPPIYKYENGSYELINVDKEGFVRDPETGEYTGWRVFKWKPFPGFFPTNGRIDSTFIRLPEKFRKKNGEFDLNLYKKNLAILECAMKGVAPGETCSGTEVGDFIMPFRYEGDASDVEVVVYQYPPGTEFAHPLYYLDPENTLSFKSLRIKEMRYMKKLAYADTRTGTGEEEEEEGTFFWDKGRFFNDSGYWEMRAFIEDKNGYLRPQSPEESKFCIACHGGIGGTVDGTFTLWRKIPGEEGWKEQDYKNIKDYRYKAITCENLDSLEMGEEVKKALEAYCSKVGESPGEYTVYFALTAGGDHFRSNYEILQDISVDGKVDLELLYNPEKIKFIDNSGFIKPELFFPEPERAYGIDKQYYRIVKAQAFIYGRDVFEKAFGISSGGNSLEELDNLESTGVKESGIWNFVKNFLSSE
What are the official names of this protein?
Uncharacterized lipoprotein aq_1262.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GRPE_CHLTE
Sequence: MSRKHHKEQEEIQEQETISAGAAETPAEETAAIPAATEADMDAEISARDAEIQKLREEVMRRAAEFENFRKQKEREAALSGTRMLENIVRELLPLIDDLKRLMSHIPAEMQAMAEAKPFIEGVELIHKNFMSLLERKGVKEIEAKGKMLDVNFHEAITQIDAPGAEPDTIVEEYQTGYTLGDRVIRHAKVIVAK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_MYCS2
Sequence: MGIPDDPAGSAPENFDLATMRVEYVEKDGCGDLDVDWLGDDPATGWLTLLQTWINDAWKAGLPDANAMVVGTVDADGRPVTRSVLCKSVDPDGITFYTNYDSAKGEHLAVNAYASATFPWYQLGRQVHVRGAVTKVSAEETAEYWSKRPRGSQLGAWASQQSRPIASRAALLEQLAEVTERFADLDEVPVPPNWGGYRIAPEVVEFWQGRENRVHNRIRVTGGRVERLQP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RPOZ_HYPNA
Sequence: MARVTVEDCIQKVPNRFELVLLAAHRARMIREGSPLTIDRDNDKDPVVSLREIAETSIDLKVVKEALISNLQDIRPGEENEREADRVALQAAPAATEDDVLRAYQAELESGRDDRL
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.