PharMolix/UniProtQA huggingface dataset:
Protein: SPLB_STAA9
Sequence: MNKNVVIKSLATLTILTSVTGIGTTLVEEVQQTAKAENNVTKIQDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
What is the function of this protein?
Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln.
What are the official names of this protein?
Serine protease SplB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEM3D_CHICK
Sequence: MRASQVPNACSLLSLAMLFFPVTGTSKQNIPRLKLSYKDLLLSNSCIPFLGSTEGLDFRTLLLDEERGRLLVGAKDHIFLLNLVDLNKNVKKIYWPAAKEKMELCKLAGKDAHTDCANFIRVLQPYNRTHVYVCGTGAFHPLCGYIELGTHKEETIFRLDTQNLESGRLKCPFDPQQPFASVMADEYLYAGTASDFLGKDTALTRSLGPSHDHHYIRTDISEHYWLTGAKFIATFPIPDTYNPDDDKIYFFFREISQDSSTSDKTILSRVGRVCKNDMGGQRSLINKWTTFLKARLVCSIPGPEGADTHFDELQDIFLLSTRDERNPLVYGVFTTTSSVFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYEGRIPYPRPGTCPSKTYDPLIKSTRDFPDEVISFIKRHPLMYKSVYPLTGGPVFTRINVDYRLTQIVVDHVMAEDGQYDVIFLGTDIGTVLKAVSITKEKWTKEEVVLEELQIFKHPSFISTMEISQKQQQLYIGSRDGLVQLSLHRCHTYGKACADCCLARDPYCAWDGNSCSRYAPTSKRRARRQDVKYGDPVAQCWDVEDSISHETADEKVIFGIEFNSTFLECIPKSQQASIRWYIQRSGEEHREELKADERIIKTEHGLLIRSLQRRDAGAYFCKAQEHTFIHTIVKLNLNVIENGQMESTQKTEDEEGRVRDLLTESRLRYKDYIQLVSSPSFSLDEYCEQMWHREKRRQRNKGGAKWKHVQEMKKKRNRRHHEPARPPST
What is the function of this protein?
Induces the collapse and paralysis of neuronal growth cones.  Could potentially act as repulsive cues toward specific neuronal populations.  Binds to neuropilin.
What are the official names of this protein?
Semaphorin-3D, Collapsin-2, COLL-2.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PHYDA_SHIBS
Sequence: MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEIDATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCRLRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKLNDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAEAIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYDTEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCPNGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVVIIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRFLRRKPFVPPVL
What is the function of this protein?
Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives with an aromatic side chains at the 5'-position.  Has no activity on dihydropyrimidines.  The physiological function is unknown.
What are the official names of this protein?
D-phenylhydantoinase, Hydantoin-utilizing enzyme HyuA.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Protein: ANGL4_RAT
Sequence: MRCAPTAGAALVLCAATAGLLSAQGRPAQPEPPRFASWDEMNLLAHGLLQLGHGLREHVERTRGQLGALERRMAACGNACQGPKGTDPKDRVPEGQAPETLQSLQTQLKAQNSKIQQLFQKVAQQQRYLSKQNLRIQNLQSQIDLLTPTHLDNGVDKTSRGKRLPKMAQLIGLTPNATRLHRPPRDCQELFQEGERHSGLFQIQPLGSPPFLVNCEMTSDGGWTVIQRRLNGSVDFNQSWEAYKDGFGDPQGEFWLGLEKMHSITGDRGSQLAVQLQDWDGNAKLLQFPIHLGGEDTAYSLQLTEPTANELGATNVSPNGLSLPFSTWDQDHDLRGDLNCAKSLSGGWWFGTCSHSNLNGQYFHSIPRQRQQRKKGIFWKTWKGRYYPLQATTLLIQPMEATAAS
What is the function of this protein?
Mediates inactivation of the lipoprotein lipase LPL, and thereby plays an important role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism.  Has higher activity in LPL inactivation than the uncleaved protein.
What are the official names of this protein?
Angiopoietin-related protein 4, Angiopoietin-like protein 4, Hepatic fibrinogen/angiopoietin-related protein, HFARP.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Note=The unprocessed form interacts with the extracellular matrix. This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4.
Protein: DHAS_RICFE
Sequence: MTKKYNIAVIGATGNVGRETLNILAERNFPVNKIYAIASDNSIGREISYGEKILKISSLTNLNFDDIDIAFFCAGSEVSKEFVPKATASSCVVIDKSSLFRVDNQVPLIVPEVNLSTLTEFNTKNIIANPNCIVIPLAVALKPLDNEIKIKRVVISTYQSVSGAGKAGMDELYDQTKSKYVFGENDPKKFPKQITFNLFPHIGDLNKDGYTSEEAKIAFELNKIMGNHFKASVTSVRVPVFIGHSISVNIEFNDKMDANIAEEILQDADGIVTISNNNDLAYISPVEVVGEDAVYVSRIRNDVSKPNAINLWITCDNLRKGAALNSVQIAEELINNYL
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: SYP_PYRFU
Sequence: MVERKKWSENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTDHQEVLFPALIPETEFQKEAEHIAGFEGEVFWVTHAGHEPLDVRLVLRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKKLAIAYVISKRPEWDKFPGAYYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKGSEEEVYSYAREIEEELKLAGIRVHLDLRDKRPGWKFYDWELKGVPVRIEVGPRDAAEKTVVLARRDKLEKITVSREELVDKVRELFDDIMQYLYERAKEWLESHIKRVDTIEEAKELFNDRRGIVEIPWCGEEECGLKMEEELEAKMLGIPYPEESARVEGKKCPVCGREAKFIARFARTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSBW_LISMC
Sequence: MATMHDKITLQLPAKPEYVSLGRLSLSGIASRAGFSYEAIEDLKIAVSEAITNSVKHAFKGEDDGEITVEYLIYEDKLEVRVSDNGTSFDLETRKQEIGPYEVGEDAEMMRIGGLGLFLIETLMDDVKLYYDEGVSVVMTKYINEKQVEENAKSIST
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: CC110_MACFA
Sequence: MSPEKQPQEEDEVDSVLLSASKILNSSEGVKESGCSGTEYGCIAESENQIQPQSALKVLQHQLESFQALRMQTLQNVSMVQSEISEILNKSIIEVENPQFGSEKNLAFGARIEKDLPTENQEGNLSMEKSRHFKDSKTLHSVEEKLSGDSVNSLSQNINVPSQMHFEDTLTLRTSTDNLSSNIIIHPSENSDILKNYNNFYHFLPTAPQNVMSQADTVILDKSKITVPFLKHGFCENLDDICHSIEQMKEELQKSHDREVALANELQTLKTDPNVQSNDKYDLSPIHQEKMNFIKEENMDGNLNEDIKSKRISELEALVNKLLPFRETVSKFHVNFCRKCKKLSKSEIHRGKRNEKNNKEIPITGKNITDLKFHSRVPRYTLSFLDQTKHEMKDKERQPFLVKQGSIIFENEKTSKVNSVTEQCVAKIQYLQNYLKESVQIQKKVTELENENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLSKTEEDSKECLKELKKIIGKYNVLQGQNKTLEEKNIQLSLEKQQMMEAFDQLKSKEHKTQSDMAIVNNENNLMSIEMEAMKTNILLIQDEKEMLEKKTHQLLKEKSSLENELKENQLEVMQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESAAARQIMEREIENIQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEMLSKMVMETKTDNQILKEELKKHSQENVKFENSISRLTEDKILLENYVRSIENERDTLEFEMRNLQREYLNLSDKICSQHNDPSKSTYISRREKFHFDNYIHEDISSPRSRPLASDLKGYLKVKDRTLKHH
What are the official names of this protein?
Coiled-coil domain-containing protein 110.
What are the subcellular locations of this protein?
Nucleus.
Protein: LOLB_SHEDO
Sequence: MPVNLNHTLLLCLLVAASLLSGCSSTLGEQYQTLNVSQSKQAKAWELQGKIAVKSPTDKFSTNLYWFHLGEENQLSLTTMLGTTVLTLNSKPGLARLEVDGKEYVDSNPQDLLEAVSGWSIPLDNLPLWITGQVGVNDEISAYHDDGLIKSLISPAPEHNWQVSFLSWQQQSGASVPKQIKIERAGVQVRIQINRWQALKTQQ
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: KRA62_MOUSE
Sequence: MCCNYYGNSCGYGCGYGSGYGSGYGCGSGSGYGCGYGSGYGCGYGSGYGCGSGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGSGYGSGYGSGCGCGYGSYYRSGCCGYGPSCYRRCYSCC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 6-2, High-glycine tyrosine keratin type II.4, HGTp type II.4, HgtpII.4.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 6 family.
Protein: GLGA_ALBFT
Sequence: MKVLYVCTELFPFLKTGGLADVSAGLAPALQAVGCEVRLLLPAFPAIANQALSTRPIASLPAGPMPWGPAPVLPPASLTLATLPGLELPVYLVQAPALYDRPGNPYLGPDGKDWSDNAIRFAALGWAGATLGQGLDPHWRPDVIHCHDWHSGLTPTYVRAFAAAKQATPATVFTIHNLAYQGLFAAAEVTRLGLPKSWFDIDGFEFFGKVSFMKAALRYADRITTVSPTYAREISSEAQGCGLDGLLRERANSLSGILNGVDDLIWNPATDALLPAPYDEHKLQGKTLAKRALQTKFGLEPRANALVFGAVSRLTEQKGLHLLPQVLADMVQRGGQLALLGQGDVALERAFVDAAIRYPGQVGVRIGYDEVTAHAVIAGADVILVPSEFEPCGLTQLYGLRYGTLPLVRRVGGLADTVVDCTLENLDEGSATGFVFDELSPAGLLSAVRRAFVLFRRPDEWLAVQQRGMGLRFDWLASAQHYLAMYQTLRPGAK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: RRP36_BOVIN
Sequence: MRRASSCGGAVAGSPSEAQDGGEDDGSLRNDTSHMSFEELLELQSQVGTKAYKQLVTGSSTKKQSSRPPVQKGCVADKHRPLEMSAKVRVPFLRQVVPISKKVARDPRFDDLSGEYNPEVFDKTYQFLDDIRAREKELVKKQLKKHRSGEEHEKLQHLLQRMEQQEMAQKERKRQQELRLALKQERRAQAQQGHRPYFLKKSEQRQLVLAEKFKELKRSKKLESFLSRKRRRNAGKDRRHLPLSKE
What is the function of this protein?
Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA.
What are the official names of this protein?
Ribosomal RNA processing protein 36 homolog.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NHAP2_PSEMY
Sequence: MDASAINNLFLIGALLVAASILVSAFGTRFGIPILVIFLAVGMLAGTDGPGGIVFNNYPLAYLVGNLALAVILLDGGMRTRVSSFRVALWPSLSLATVGVVITAGLTGLAAAWLFNLTLLEGLLIGAIVGSTDAAAVFSLLGGRGLNERVSSTLEIESGSNDPMAVFLTVTLIAMLASGQTGFSWDLPIQLVQQFGLGALLGLGGGWLLLKLINRMELATGLYPLLVVSGGLIIFAITTAVGGSGILAIYLCGLLLGNRPIRSRHGILHMLDGLTWLAQIGMFLVLGLLITPHELLPIALPALALALWMILFARPLSIFLGLLPFRAFHDRERIFIAWVGLRGAVPIILAVFPLMAGLPNAQLFFNVAFFIVIVSLLLQGTSLPLAAKLMRVTVPPEPAPVSRAGLEVHPTSQWELFVYRLGAEKWCIGAALRELNMPEGTRIAALFRGRELLHPSGSTRLEAGDLLCVIGHEHDLPALGKLFSQAPKRGQDLRFFGDFVLEGDAELAAVAALYGLKLDGLDGHQPLGRFIAHEIGGEPVVGDQVEWQGLTWTVASMEGNKVRKVGVRFPEGSRPGPGLFL
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU6C_OENEH
Sequence: MDLPGPIHDFLLVFLGSGLIVGGLGVVLLTNPIFSAFSLGLVLVCISLFFSLSNSYFVAAAQLLIYVGAINVLILFAVMFMNGSEYSKDLTLWTVGDGITSLVCTSIFISLITTILDTSWYGIIWTTKSNQIIEQDLIGNSQQIGIHLSTDFFLPFELISIILLVSLIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MANA_STRMU
Sequence: MAEPLFLQSQMHKKIWGGNRLRKEFGYDIPSETTGEYWAISAHPNGVSVVKNGVYKGVPLDELYAEHRELFGNSKSSVFPLLTKILDANDWLSVQVHPDNAYALEHEGELGKTECWYVISADEGAEIIYGHEAKSKEELRQMIAAGDWDHLLTKIPVKAGDFFYVPSGTMHAIGKGIMILETQQSSDTTYRVYDFDRKDDQGRKRALHIEQSIDVLTIGKPANATPAWLSLQGLETTVLVSSPFFTVYKWQISGSVKMQQTAPYLLVSVLAGQGRITVGLEQYALRKGDHLILPNTIKSWQFDGDLEIIASHSNEC
What are the official names of this protein?
Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 1 family.
Protein: PYRH_BACFR
Sequence: MAKYKRVLLKLSGESLMGEKQYGIDEKRLAEYAAQIKEIHEQGVQIGIVIGGGNIFRGLSGANKGFDRVKGDQMGMLATVINSLALSSALVAAGVKARVLTAVRMEPIGEFYSKWKAIECMENGEIVIMSAGTGNPFFTTDTGSSLRGIEIEADVMLKGTRVDGIYTADPEKDPTATKFHDITYDEVLKRGLKVMDLTATCMCKENNLPIVVFDMDTVGNLKKVITGEEIGTLVHN
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLTP1_NIGSA
Sequence: ISCQDVKQSLAPCLPYVTGRAPKPAPGCCNGINHL
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes (By similarity).  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).  Inhibits the growth of F. oxysporum and P. infestans (PubMed:19621049, Ref. 1).
What are the official names of this protein?
Non-specific lipid-transfer protein 1, LTP 1.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: CODY_STRMU
Sequence: MANLLSKTRRITSILQRSVESLQSDLPYNTIADQLAEIIDCNACIIDGSGIILGYAMKYKTNTDRVEEFFQAKKLPDDYVKSASRIYDTEANLSVENDLTIFPIESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDKEFNDDDLILIEISSTVVGIQLLNLQTENLEETIRKQTAINMAINTLSYSEMKAVAAILNELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKDYS
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAMP3_RAT
Sequence: MPGQTSAVAVLLCLAVILHGYQIREKEFPEARGYLQYTATTTEQITAKPPLPLTNQTSHATLASRSKDDYIQTAAETSTFEDTAHITMKTAIPVTTKSLLPISSTSYTFVRTNNSHMTASSTEDTIGSGSITHLPFPTTRASLAAVNHITGRSTQLGGQTTLPKALFTPSHESTTTQRPTLSTIVSELTPTGKDRSTTSSVPLVPRPTFVTWSSPAKIGTYEVLNGSRLCIKAEMGIALIVQEKGLDSATQRHFNIDPSLTHASGKCGSQNSNLFLNFQGGSVNVTFTKEENLYYVSEVGAYLTISNTEKTYQGKSTMMMFETVVGHSFKCVSEQSIQLSAQLQMKTMNIHLQAFDFEGDSFGIVDECLSDYTVVLPVVGIIVVVLCVVGLGIYKIRQRRQSSAYQRI
What is the function of this protein?
Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction.  Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process.  Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway.  May also play a role in dendritic cell function and in adaptive immunity.
What are the official names of this protein?
Lysosome-associated membrane glycoprotein 3, LAMP-3, Lysosomal-associated membrane protein 3.
What is the protein family that this protein belongs to?
Belongs to the LAMP family.
What are the subcellular locations of this protein?
Cell surface. Lysosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Note=During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3. Detected on lysosomes in mature dendritic cells.
Protein: UVRB_ZYMMO
Sequence: MTIAIRTTLDEPENHSDFVPHRPSRPEKTEPSKPFRLVSDYEPAGDQPQAISALCKDIQKGERDQVLLGVTGSGKTFTMAKVIEKLQRPSLILAPNKILAAQLYGEFKRFFPENAVEFFVSYYDYYQPEAYVPRTDTYIEKDSAINEAIDRMRHAATRSLLEREDVIIVASVSCLYGIGSVDTYSSMTFRLLKGQLVDQREIIRRLVALQYKRNEVAFGRGSFRVKGDTLEIFPSHYEDMAWRISFFGDEIEEISEFDPLTGVKIAKLDQIKIYANSHYVTPEPTLKAANNAIRRELDNRLREFKAEGKLLEAQRLEERTEFDLEMMAATGACSGIENYSRFLTGRAPGEPPPTLFEYLPDNALLFVDESHQTIPQINGMSRGDYRRKTTLADYGFRLPSCIDNRPLRFEEWNAMRPQTVYVSATPGPWELEQTGGVFVEQIIRPTGLVDPAIEVRPIEEQVDNLIFEAKKTAAAGWRSLVTTLTKRMAEDLTEYMYEAGLKVRYMHSDVETIERIELIRDLRLGVYDVLIGINLLREGLDIPECGLVAVLDADKEGFLRSETSLIQTIGRAARNAEGRVILYGDKITGSMARAMAETERRRIKQIAWNKAHNITPATVKRQVDDIVGHFGVVNSSEAAATIENHDPKVLARSISETEKEMLEAAANLEFEKAAQLRDVLHQLKRQELGLPPEKSSEIQGRSEAGRPGTRKTRSDKAREAKASKRVKQEAGEKLLRSRGH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK1_LUCVE
Sequence: GSTGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, LucVe-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y5537_ARATH
Sequence: MKSTFLLLLLLLSLNLLFVFVSCASSIEFVYPNFTASNLRFVDSSKGAFLLSRNSIFKAGLFSPGGDDSSTGFYFSVVHVDSGSTIWSSNRDSPVSSSGTMNLTPQGISVIEDGKSQIPVWSTPVLASPVKSLRLTDAGNLLLLDHLNVSLWESFDFPTDSIVLGQRLKLGMFLSGSVSRSDFSTGDYKFLVGESDGLMQWRGQNYWKLRMHIRANVDSNFPVEYLTVTTSGLALMARNGTVVVVRVALPPSSDFRVAKMDSSGKFIVSRFSGKNLVTEFSGPMDSCQIPFVCGKLGLCNLDNASENQSCSCPDEMRMDAGKGVCVPVSQSLSLPVSCEARNISYLELGLGVSYFSTHFTDPVEHGLPLLACHDICSKNCSCLGVFYENTSRSCYLVKDSFGSLSLVKNSPENHDLIGYVKLSIRKTNAQPPGNNNRGGSSFPVIALVLLPCSGFFLLIALGLLWWRRCAVMRYSSIREKQVTRPGSFESGDLGSFHIPGLPQKFEFEELEQATENFKMQIGSGGFGSVYKGTLPDETLIAVKKITNHGLHGRQEFCTEIAIIGNIRHTNLVKLRGFCARGRQLLLVYEYMNHGSLEKTLFSGNGPVLEWQERFDIALGTARGLAYLHSGCDQKIIHCDVKPENILLHDHFQPKISDFGLSKLLNQEESSLFTTMRGTRGYLAPEWITNAAISEKADVYSYGMVLLELVSGRKNCSFRSRSNSVTEDNNQNHSSTTTTSTGLVYFPLYALDMHEQGRYMELADPRLEGRVTSQEAEKLVRIALCCVHEEPALRPTMAAVVGMFEGSIPLGNPRMESLNFLRFYGLRFAESSMVEGQNGESETMVFHRRESSNSGGSRQSASYIASQEVSGPR
What are the official names of this protein?
G-type lectin S-receptor-like serine/threonine-protein kinase At5g35370.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ACCD_STAA8
Sequence: MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEILKIHQEVTK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTA_SALG2
Sequence: MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACATLLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALIDCLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPIIA_COLGM
Sequence: MKFSIGVSLLATLAGAVNVDMAKRDTSPLNVKLEALGNSGVKAVLTNTGDSDIKLFKTGTFLDKSPVEKVEVFAAGSKIDFDGVRLQISTTGLTEEAFQIVAAGETFEVEFDAAELHDLSKGGAVDIVTQGSFLYADVDSTEIAGTIPFSSNSVHTEINGDEAASVRAAFLAKRTIVQSDCTGTRRTATVNAISRCRALAAAASQAAASGPVARMTEYFKSSTTATRNSVATVFRNIVSECGSTTSGVSRQYCTDVYGACSNGVIAYTVPAQNYMVNCPYFFNNMAAASSTCHAQDQQTTILHEMTHLRQIKGTSDYGGYGYNFVRSLSAAQNLNHADTYTLFAQSIYAGC
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog MGG_10927, Deuterolysin MGG_10927.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BGBP2_DROME
Sequence: MRWEFLPCLLLLISNNKIFGFKVPSINFEMLKDEGFEVSIPDEPGIQRVFYMFQIDDTCPALMDYITEAVNGSWVSKQKMSLQNNDKLQISMLVQFNEEIFEKSETRVIINTRLLTTKDSSSRGITFLTGEGECQAYLAPAQQAKRCKAAQTIVSNGRHTCQGELIFEDNFSEAQLNKTTWKHDIRQRMYHVEEELVAFDDAARNCFVKEGELHIVPTIATEVTDGSFKLGDRCTAVESPEQECNIAHGIFYSIKPPVFSAQIHTRNSFSFKFGKIVVRAKLPKGDWLFPYLMLQPVSTYAETHYAKQLRIAYARGNANLRTKQGDDISGNHLYGGGVVWHHGNAVQFLKDKISNSHYGDDFHNYTMIWQRDKITLMVDDEVYGELYDGLPFFNEKCFIIFGVTVGGFLNFDDSLLAKDVKPYKNREPRAALSFWQHRDAWAPTWGRHSAMVIDYVRVYAE
What is the function of this protein?
Involved in the recognition of invading microorganisms.  Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade (By similarity).
What are the official names of this protein?
Gram-negative bacteria-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the insect beta-1,3-glucan binding protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y543_RICCN
Sequence: MKKFIFCFLCLWTLNIFAASKTYPNKLNRCKITRNIFNDYEPKVFETTNNLLRKTGRLSKFYGERILIKGKVLDQNCVPVADAKVYLWQAGSGGKYPYEPLKTRVDKRRFTSKSDSSFTGSGIATTNNKGEYYFISMLPYTSSRYLRSANIRIEHPSLTTLETRLDLSDQNMCDNECGEVNPILIEPQENMPSYCFDLVLQGTTLKRY
What are the official names of this protein?
Putative dioxygenase RC0543.
What is the protein family that this protein belongs to?
Belongs to the intradiol ring-cleavage dioxygenase family.