PharMolix/UniProtQA huggingface dataset:
Protein: KHTS_BACSU
Sequence: MRREERNMDKLLISFLLSLFMVYFPPSDVVLPSQFEASTDSYVPMSSYPQETQSAKTPSPGSMHPAELIKEYSPLAQSVRQLSVKPLDEPLINRLEKALAVPVKYQSNYLRI
What is the function of this protein?
Modulates the activity of the potassium/proton antiporter KhtU (PubMed:14987767).  Involved in protection of the cell from methylglyoxal, a toxic by-product of glycolysis (PubMed:24330391).
What are the official names of this protein?
K(+)/H(+) antiporter modulator KhtS.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PONM_DICDI
Sequence: MKFLSTLILLLSVLALVRGEQYNKFTVDLNGVCTNSGSLDTCTNQCGNAGGSFQISQSGGEYQYEQYATKDCDLMASLTSKFACLADEAPVTLGLGNIKITCQDPSNSASSPLTTAVLFVVAFAAAIALLL
What is the function of this protein?
Binds F-actin and nucleates actin assembly.
What are the official names of this protein?
Ponticulin-like protein M.
What is the protein family that this protein belongs to?
Belongs to the ponticulin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: DPOE3_PONAB
Sequence: MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDN
What is the function of this protein?
Accessory component of the DNA polymerase epsilon complex (By similarity).  Participates in DNA repair and in chromosomal DNA replication (By similarity).  Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 (By similarity).  Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex (By similarity).
What are the official names of this protein?
DNA polymerase epsilon subunit 3, DNA polymerase II subunit 3, DNA polymerase epsilon subunit p17.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPX2_ARATH
Sequence: MSDLDKQIEQLKRCEALKESEVKALCLKAMEILVEESNVQRVDAPVTICGDIHGQFYDMKELFKVGGDCPKTNYLFLGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVNVWRYCTDIFDYLSLSALVENKIFCVHGGLSPAIMTLDQIRAIDRKQEVPHDGAMCDLLWSDPEDIVDGWGLSPRGAGFLFGGSVVTSFNHSNNIDYICRAHQLVMEGYKWMFNSQIVTVWSAPNYCYRCGNVAAILELDENLNKEFRVFDAAPQESRGALAKKPAPDYFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP-X isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
What are the subcellular locations of this protein?
Plastid stroma.
Protein: LSS_BOVIN
Sequence: MTEGTCLRRRGGPYKTEPATDLSRWRLSNQVGRQTWTYSQEEDPVREQSGLEAHLLGLDTKSFFKDLPKAHTACRGALNGVTFYAALQTEDGHWAGDYGGPLFLLPGLLITCHVANIPLPAGYREEIIRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNLLHKKGGAVFIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWMPAHPSTIWCHCRQVYLPMAYCYSTRLSAEEGPLVQSLRQELYLEDYSCIDWAAHRNSVAPDDLYTPHSWLLHVVYAILNLYERHHSTSLRQWATQKLYEHIAADDRFTKCISIGPISKTINMLVRWHVDGPASAVFQEHVSRIPDYLWLGLDGMKMQGTNGSQIWDTAFAIQALLEARAQHRPEFWSCLRKAHEYLRISQVPDNFPDYQKYYRHMSKGGFSFSTLDCGWIVADCTAEALKSILLLQEKCPFVSNHVPRERLFDTVAVLLSLRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKTFHKQFPDHRAGEIRETLEQGLQFCRQKQRPDGSWEGSWGVCFTYGAWFGLEAFACMGHTYHNGVACAEISRACDFLLSRQMADGGWGEDFESCKQRRYVQSAQSQIHNTCWALMGLMAVRHPDVAALERGVSYLLEKQLPNGDWPQENISGVFNKSCAISYTSYRNVFPIWTLGRFSRLHPDPALAGHP
What is the function of this protein?
Key enzyme in the cholesterol biosynthesis pathway.  Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus (PubMed:14678783).  Through the production of lanosterol may regulate lens protein aggregation and increase transparency (By similarity).
What are the official names of this protein?
Lanosterol synthase, 2,3-epoxysqualene--lanosterol cyclase, Oxidosqualene--lanosterol cyclase, OSC.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: EXOG_HUMAN
Sequence: MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQIRKPS
What is the function of this protein?
Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.
What are the official names of this protein?
Nuclease EXOG, mitochondrial, Endonuclease G-like 1, Endo G-like 1.
What is the protein family that this protein belongs to?
Belongs to the DNA/RNA non-specific endonuclease family.
Protein: CARA_HELPY
Sequence: MVSLYLENGLFLQAQSFGASGTQAGELVFNTSMSGYQEVISDPSYKGQFVVFSMPEIGVVGANSKDDESFFSCAGVLARHYNEFFSNSRADFSLSAYLKERGVLGVCGVDTRSLIKTLRHHGCLMMVASTIEHDKNKLEEILKNAPKISHSPLVSSVSTPKITTHQRATFDFKTLDYKPFDEKTSHKIIAVLDFGAKGNILNELQNVGLKALIYPHHTKASELIKAYEKKEISGIFLSNGPGDPLSLQQEIGEIKQLINAKIPMLGICLGHQLLSIAQGYPTYKLKFGHHGSNHPVKNLKTNAVEITAQNHNYCVPEDIEEIAIITHRNLFDNTIEGVRYKNAPIISVQHHPESSPGPKESHYIFKEFVELLKDF
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: COAD_SALCH
Sequence: MQKRAIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPGKKPMFTLDERVALAQKATAHLGNVEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQLAHMNRHLIPQLESVFLIPSKEWSFISSSLVKEVARHQGDVTHFLPDNVHQALMDKLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_DELAS
Sequence: MSLRIYNTLSRALEAFSPIEPGHVRMYVCGMTVYDLCHLGHARSMVAFDVVQRWLRASGHRVTYVRNITDIDDKIIRRAVENGETIRSLTDRMIDALHQDADALGIERPTHEPRATEYVPQMLSMIGRLQDKGLAYQGTDGDVNFAVRKFPGYGKLSGKSLDELQAGERVAVQDGKQDPLDFVLWKSAKPAEPEEVKWASPWGVGRPGWHIECSAMGCEMLGESFDIHGGGADLQFPHHENEIAQSEGATGKPFSQVWMHNGFINVDNEKMSKSLGNFFTIRDVLKEYDAETVRFFVVRSHYRSPLNYSDVHLNDARGALKRLYTALSLVAPAEVAVDWNHPAAARFKAAMDEDFGTPEAVAVLFELAAEVNRSKSAETAGLLKALAGCLGLLQGDPQAFLQAGTSEMDAGAIEAQIAARAAAKAAKDWAEADRIRKALLEQGIVLKDSPAGTTWEAAAKG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_NITMU
Sequence: MTVPEIFDVIVIGGGHAGTEAALAAARIGQKTLLLSHNIETLGQMSCNPSIGGIGKGHLVKEIDALGGVMAEAADEAGIQFRILNSRKGPAVRATRAQADRVLYRQAIRQRLESQPNLWLFQQGVDDLVLEGERVAGVVTQLGIRFNARAVILTAGTFLAGLAHVGSANFQAGRAGDLPSNSLAGRLRELKLPVGRLKTGTPPRIDGRTIDYSAVAAQPGDAPVPVFSFMGNAASHPKQVSCWITHTNSQTHDIIRSGLDRSPLFSGAIEGIGPRYCPSIEDKVVRFSAKESHQIFLEPEGLTTHEVYPNGISTSLPFDMQVKLVRSIKGLENAHITRPGYAIEYDYFDPRALKSSLETRMIEGLFFAGQINGTTGYEEAAAQGLLAGINAALKTQDREPWCPRRDEAYLGVLVDDLITRGVTEPYRMFTSRAEYRLQLREDNADLRLTEVGRRLGVVNDARWVAFNIKLEAIAQEQNRLKTTWLSPKSLSETDALRVIGKNIEHECSLHDLLRRPNVSYAELMTLPGAGEPVVDLAAAEQVEIQAKYQGYIERQKDEVARNAYYEDIRLPQDLDYKTVRGLSNEVQQKLNQFKPETAGQASRISGITPAAISLLLVHVKRGFSSANTKKSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CY550_PHATC
Sequence: MFKKSSQLFSLVFFTIFSIFIGTASAIDLDEATRTVVVDSSGKTIVLTPEQVKRGKRLFNATCGACHVGGVTKTNPNVGLDPEALSLATPRRDNIAGLVDFLKNPTTYDGLESIAEVHPSIKSADIYPRMRSVTDEDLTAMAGHILLQPKIVTEKWGGGKIYY
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: SYD_STAAR
Sequence: MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFEAENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_CAMJ8
Sequence: MDNYEFSELLKTLKNKVGNIASIIKPENIQTRLKEIEELENSPSFWSDVKQAGIIGKEKTKITNLLKNYENAFNALNDASELFDLANSENDTETLEALFNDAPKLEDTITSLEISMLLSGENDGKNAIVSIHPGAGGTESNDWASILYRMYLRFCEREGFKVETLDFQEGEEAGLKDVSFLVKGENAYGYLKAENGIHRLVRTSPFDSAGRRHTSFSSVMVSPELDDDIEIEIEEKDIRIDYYRASGAGGQHVNKTESAVRITHFPTGIVVQCQNDRSQHKNKATAFKMLKSRLYELELMKQQDSANAGEKSEIGWGHQIRSYVLFPYQQVKDNRSGEAFSQVDNILDGDIKKMIEGVLIALKAE
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_DEHMC
Sequence: MKVTDKKIEGCQASITVEMDSTEVEEGLSKTYRRLVKKVEIPGFRKGKAPRDVFEKYVSREKMLDELVDDIVPEACQKAIQDEEIKPFATPKVAMVTTDPFVFSARIPLPPVVELGDYKTIRATKETVEIAEENIDTVVDQVLHQRATWETAERPVKMGDMLLMQVESTLNGEPYLNREDMQYSVREEAIYPAPGFGDCLVDMVAGEPKEFSIVFPEDHARAELAGKTAAFKVTVREIKEEKLPELNDAFAHELNPEFNTLSELRQRIRENMQDRQDDKAQAKFEDQIVEALIKMSKIDYPEVMVEAELDQIIEQQLQRLQSNVKSPEEFRAMLSQMTPEDMQQRYRPLAEQRVASSLVLGKLATTENLVPNDEEVDAEIEKLITDAGDKKEEEKALYNQSETRDRLIQLLTARKTMAFIDEIALQPALEAVEPKADEDEKTEEADK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: SYH_SYMTH
Sequence: MSIQAPRGFNDILPGEQYGWRDSYRWQRLEEIFREVARLYGYQELRPPMVEYVDLFIHGVGATTDIVTKEMFNITPRGDDPDARRMAMRPEFTAGLVRAWLENGLYNNPQPTKIFAYGPAFRYENVQKGRFRGFHQLDVEVFGAQDPAVDAEVIKLGLDVVARLGLTGLVVSVNSIGCPQCRPRYRQALQDHFRPHLGELCEDCNTRFEKNPLRLLDCKRDADHPAQRTAPVTLDYLCDDCRRHWEGLLSHLAAMGIPYQIDTRIVRGLDYYTKTVFEVLHPKLGAQSALWGGGRYDGLIEIVGGKPTPGVGFGMGMERVLMVLEEEGLTAPFADRPRLDVFVATLGEAARPVGLKLLYALRDAGLSADIDYLGRSLKAQMKYAGKQNSRYVVILGEDEVRQGVASVKHMDEGTQESVPLDQIISHLRRAEA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYP0_XENTR
Sequence: MESSGLRAPCSLLVLLSALVLPPTLAIEVYTDREVYGTVGSRVTLSCSFWSSEWISDDVSVTWHYQPDHSREMYSIFHYAKGQPSIDAGVFKDRIEWVGSPKWKDASIVLHNLELIDNGTFTCDVKNPPDVVGKSSYVHLQVQEKGAARAGLVLGIIIAVALALVIVVTILILLIRYCWLRRQVRVQRELSALERGKLHKAKDSSKRSSRQTPILYAMLDQTRGKASEKKGKGGIGDSRKDRK
What is the function of this protein?
Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.
What are the official names of this protein?
Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero.
What is the protein family that this protein belongs to?
Belongs to the myelin P0 protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NUSB_BURM9
Sequence: MKKSARRQSRELATQGLYQWLLSNAAPGEIDAQLRGALGYDKADKTLLDTILHGVIREHATLAEAISPSLDRPIDQLSPVERAVLLIATYELTHQIETPYRVIINEAVELAKTFGGSDGYKYVNGVLDKLAVKLRPAETQARRGA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: GPO_LACLM
Sequence: MNFYDFSAVKMNGETVSMSDYKGKVVIVVNTASKCGFTPQFEGLEKLYETYKDQGLEILGFPCNQFANQDAGENTEINEFCQLNYGVTFTMFQKIKVNGKEAHPLYQFLKKEAKGALSGTIKWNFTKFLIDRDGQVIERFAPKTEPEEMEEEIKKLL
What are the official names of this protein?
Glutathione peroxidase.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: RND_ACICJ
Sequence: MKPSPSFPEPVLIETTEALAALCDRLAAEPFVTVDTEFMREKTYFPELCVVQLGGANDVAVIDAQAEGLDLAPLGALFANPAVTKVFHACRQDIEIFLLKFGAVPAPLFDTQVAAMVAGFGDQVGYDTLVSSLAGGRIDKAHRFSDWSARPLSRAQIAYAAADVTWLRPVYEGLRARLTREGRLDWVAEEAAVLADPATYRTEPEDAWRRLKLRGGNRRQLALVKAIAAWREREAMRVNVPRQRIVRDEQIPELAALAPADAEGLTRVRGISSGFAGGKSGRALLEVIASTKAIPDAELPEAPRAPESARPPAGLVALLKVLLAERAGANHVAARLIASAEDIDRLASEDAPNLPCLQGWRAELFGNDALRLKGGRIALAARGRRVEVVDLP
What is the function of this protein?
Exonuclease involved in the 3' processing of various precursor tRNAs.  Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
What are the official names of this protein?
Ribonuclease D, RNase D.
What is the protein family that this protein belongs to?
Belongs to the RNase D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PATJ_DROME
Sequence: MHLSADISSALQQIEAVKKGIDESDDPKLQMQTAESLSTILGILQDPVFRTIVHVQDSLSELNAQLAQHPSMLPNDFDIDVAGNLVLSLNGGEVMYDFDEQRSSSHSHSAPGSPDKSGGVGEEPRPQSQNSKGAGVADLYATDYAQIQAIELVNDGTGLGFGIIGARNSGVIVKTILPGGVADKDGRLRSGDHILQIGDVNLHEMVSEQVAAVLRQSGTHVRLVVARPVEQSVPTPQYALEPGTAVVPTRVLVDPAELERYLISTGYPEIFGESSTASTPQTTTEDDRFVYRGETSMLIDPNIDLEELLALPETEKLQVELKKDANGLGITIAGYVCEKEELSGIFVKSVSPGSAADLSGRIRVNDRIIEVDGQSLQGYSNHQAVELLKKSGQVVNLRLERYLRGPKFEQLQQAIAANDKLPSSAPGTPSRAPMPTPVATTSSATTTPSRSITRELEEEALPAPEAFMTTPPSVTTMTTTTLSSFGAGKQLVAVRDSLDGSTKIIPTEVVPLADKTEAKNSGVITRHKYYTDPELSDDAETEIIRKWQKIVGSDVEVIVAQIKKFAVGGLGISLEGTVDVEGGREVRPHHYIRSILPDGPVGVNGVLRSGDELLEVNGERLLGMNHLEVVAILKELPLDVRMVCGRNRNSSLLPFSDDTLKKLSNNFENLLPATDRLVKAKSDGSLATAGSVADGDSVAAAAASFSKLKSRSLEPLTGLAMWSSQPQIIELVKGDRGLGFSILDYQDPLDPNDTLIVIRSLVPGGVAQLDGRLIPGDRLLFVNSINLENASLDQAVQALKGASKGVVRIGVAKPLPMTDNSLKACSNASTTSEETLDAQPSPPALPTVAPPAMPPSASMGAEPDLIPDWRN
What is the function of this protein?
Involved in cell polarity establishment.  Probably participates in the assembly, positioning and maintenance of adherens junctions via its interaction with the SAC complex.
What are the official names of this protein?
Patj homolog.
What is the protein family that this protein belongs to?
Belongs to the Patj family.
What are the subcellular locations of this protein?
Membrane. Note=Membrane-associated. Localizes to the subapical domain of cells. Sdt is required for its localization. At mitotic cycles 13 and 14, during cellularization, it localizes at the leading edge of the invaginating membranes. It is then exclusively localized to the basal area of columnal epithelial cells. In the germline, it localizes at the membrane of the nurse cells during early and mid oogenesis. Later, it is found in the nuclear membrane in close association with actin filaments that connect the nuclei of the nurse cells with the plasma membrane.
Protein: RL11_BURO0
Sequence: MAKKIIGFIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAQTQGMEPGLPVPVVITAFADKSFTFVMKTPPATVLIKKAAKVDKGSSKPHTDKVGSITRAQAEEIAKTKMPDLTAADLDAAVRTIAGSARSMGITVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: FIBG_CANLF
Sequence: YTATRDNCCILDERFGSYCPTTCG
What is the function of this protein?
Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix.  Has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen gamma chain.
What are the subcellular locations of this protein?
Secreted.
Protein: CEA15_MOUSE
Sequence: MGAETMESPSLFLCKGLLLTASLLICWNWSTAALLTSKEMRFSAAEGAKVLLSVPDQEENLLSFSWYKGKDVNENFTIAHYKKSSDSLQLGKKVSGREEIYKDGSMMLRAITLEDTGFYTLQTFKAHGQQEVTHVHLQVYKIVTKPYLQLNHTRLKRKSASILTCVSPDTGVDINWFFNYKPLNATERITLSPEKRELTISPVWRADVGIYLCEVSNSFSSKKSYPLLMALAYG
What are the official names of this protein?
Carcinoembryonic antigen-related cell adhesion molecule 15.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. CEA family.
Protein: HSLV_KLEP7
Sequence: MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADENASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTDMGARDIAEKALDIAGDICIYTNHFHTIEELPSKA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACNA_CORJK
Sequence: MAESINSFDSKSTLQVGEKSYDYFALDAVPGMEKLPYSLKVLGENLLRNEDGKNITREHIEAIANWDPSAEPNFEIQFTPARVIMQDFTGVACIVDLATIRDAVVALGGDADDVNPLNPAEMVIDHSVIIEAFGDSDALEKNVEIEYQRNDERYKFLRWGTGAFENFRVVPPGTGIVHQVNIEYLARSVFDNNGLAYPDTCVGTDSHTTMENGLGILGWGVGGIEAEAAMLGQPISMLIPRVVGFKLTGEIPTGVTATDVVLTITDMLRQHGVVGKFVEFYGKGVGELPLANRATIGNMSPEFGSTAAMFPIDEETVKYLELTGRDQETLERVEAYAKAQGMWLDPEKEVEYSEYLELDLSTVVPSIAGPKRPQDRIELNDSKAQFRKDLHNYVEADASAVTPDFDAEGPATENTSAQTAGTPASAADAKGNIPSAAAGAEGRPSNPVTVNYNGEDIELDHGMVAIASITSCTNTSNPSVMVGAGLLARNAAAKGLKSAPWVKTSMAPGSQVVNGYYEKAGLWKDLEAMGFYLVGYGCTTCIGNSGPLPEEISAGINEGDLAATAVLSGNRNFEGRINPDVKMNYLASPILVIAYAIAGTMDFDFETQPLGQDQDGNDVFLKDIWPSTEDIEEVIASSITKDLYAEDYANVFEGDERWRSLDVPSGKTFDWDPKSTYIRKAPYFDGMSKEPEAVNDVKGARVLALLGDSVTTDHISPASTIKPGTPAAQYLDANGVERKDYNSLGARRGNHEVMVRGTFANIRLQNQLLDGVSGGYTRDFTQEGGPQSFIYDAAMNYQKENTPLVVLGGKEYGTGSSRDWAAKGTLLLGVKAVIAESFERIHRSNLIGMGVVPLQFPEGESWKSLGIEGTETFDIEGIEELNNGSTPKTVKVTATKENGEKIEFDAVTRIDTPGEADYYRNGGILQFVLRNMMSGK
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The apo form of AcnA functions as a RNA-binding regulatory protein.
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, Iron-responsive protein-like, IRP-like, Probable 2-methyl-cis-aconitate hydratase, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: RABP2_CHICK
Sequence: MPNFSGNWKMKSSENFEELLKALGVNMMLRKIAVAAA
What is the function of this protein?
Transports retinoic acid to the nucleus.  Regulates the access of retinoic acid to the nuclear retinoic acid receptors (By similarity).
What are the official names of this protein?
Cellular retinoic acid-binding protein 2, Cellular retinoic acid-binding protein II, CRABP-II.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Nucleus. Note=Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.
Protein: TGL_BACCN
Sequence: MIVIGRSIVHPYIMNENEPFAAEKQQFLSIMTGNQEVYSFRTAAELSFDLNVRMHIITSALELFQSGFQFRTFVTSFCNEEYWQRTALGGFQLRPGVSSSIAIRDIFKNGKMYGTECATAMIIIFYKALLELYDEEMFNHLFANLLLYTWDYDRDLKLITKTAGDIVPGDLVYFKNPQVNPASIEWQGENAIYLGNSFYYGHGVGVKTKEQIIYLLNDRRIPSAFISAYLTDFITRIDSRIMSQYASHTPPQTSLGFIPIRDDAIVATIGHTTTIY
What is the function of this protein?
Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase, Transglutaminase, TGase.
What is the protein family that this protein belongs to?
Belongs to the bacillus TGase family.
Protein: YCR2_YEAST
Sequence: MENRCSNPCYIQSDPSDLLSLRLPARFCWPFSRSSRIFQGSSRRRILSEGKNASKACFVRIFGMAKVSKAISRSRSRLLFRSLPPHPACLFEYQISSSSLFHHPFLLWQGQVFF
What are the official names of this protein?
Uncharacterized protein YCR022C.
Protein: ZGPAT_MOUSE
Sequence: MDEDNLETALQTYRAQLQQVELALGAGLDASEQADLRQLQGDLKELIELTEASLLSVRKSKLLSTVDQESPAQEDAEYLAFQKAIAEEVEAPGAPCNDSETAPGSEVQPGSTSSALEEEEEDPDLEELSGAKVNAPYYSAWGTLEYHNAMVVGAEEAEDGSACVRVLYLYPTHKSLKPCPFFLEGKCRFKENCRFSHGQVVSVDELRPFQDPDLSLLQTGSACLAKHQDGLWHPARITDVDNGYYTVKFDSLLLKEAVVEGDSILPPLRTEATESSDSDTGDASDSSYARVVEPSTVDTGTCSSAFAGWEVHTRGIGSKLLVKMGYEFGKGLGRHAEGRVEPIHAVVLPRGKSLDQCAEILQKKTKRGQAGSNRPPKCRRSGSRPEGRPPPRNVFDFLNEKLQSQVPGTPDAGVDTPERRNKDMYHASKSAKQALSLQLFQTEEKIERTQRDIRGIQEALTRNTGRHNMTTAHLQEKLEGAQRQLGQLRAQEADLQRKQRKADTHRKMTEF
What is the function of this protein?
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence.  Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters.  Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration.  Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity).
What are the official names of this protein?
Zinc finger CCCH-type with G patch domain-containing protein.
What are the subcellular locations of this protein?
Nucleus.