PharMolix/UniProtQA huggingface dataset:
Protein: OSER1_MOUSE
Sequence: MKSEAKDGEEESLQTAFKKLRVDASGSIISLSVGEGPSVRASARTAADDTKPKTMCASKDSWHGSTRKSSRGAVRTQRRRRSKSPVLHPPKFIHCSTTAPPSSSQLKHRSQTEPPDGISGRGISTPKEFNAGENSTSLDVNHTGAAIEPLRSSVLRLPSESKTEELSDATQVSQESLTANDLSDFQSVSKLSQGKPCVCVGKECQCKRWHDMEVYSFSGLQNVPPLAPERRSLEDYSQSLHTRTLSGSPRSCSEQARVYVDDVTIEDLAGYMEYYLYIPKKMSHMAEMMYT
What are the official names of this protein?
Oxidative stress-responsive serine-rich protein 1, Oxidative stress-responsive protein 1, Peroxide-inducible transcript 1 protein.
Protein: RL15_VIBCM
Sequence: MLLNTLSPAAGSKHAPKRLGRGVGSGLGKTGGRGHKGQKSRSGGKVRPGFEGGQMPLKQRLPKFGFTSRKSFVSAEVRLSELAKVTGDVVDLNALKAANLVTKNIEFAKIVLSGEINKAVTVKGLRVTKGAKAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: BCSA5_KOMXY
Sequence: MYGTWFTTGKVTDLLARTGLDRVPVWVPVVLGVVLMAFVGSVRIDPALQGWVSIGTVTLLLVLNRRRGRGITVFLMMLSLLVSLRYIVWRLTATVQFSNWLQTALAVLLLLAEAYALMTLCLSYFQMAWPLRRREHPLPEDMAQWPSVDVFVPSYNEELSLVRSTVLGALDLDWPADRLNVYILDDGRRKAFHDFAVEAGAGYIIRAENNHAKAGNLNHALAVTDSPFAVIFDCDHVPTRGFLRRTIGWMMADPNLALLQTPHHFYAPDPFQRNLAGGMHVPPEGNMFYGLVQDGNDFWDATFFCGSCAIIRREAVMGIGGFATETVTEDAHTALKMQRRGWGTAYLREPLAAGLATERLILHIGQRVRWARGMIQIMRLDNPMLGAGLRWEQRLCYLSAMSHFLFAIPRLTFLVSPLAFLFLGQNIIAASPLAISVYALPHIFHSVITLSRIEGRWRYSFWSEIYETSLALFLVRITIVTLLQPHKGKFNVTDKGGLLARGYFDWDAVYPNVILAGVLCAALLRGVFGIVWQFHDRLALQSFILNTLWVVISLIIVLASIAVGRETRQTRNAPRVSVRLPVVVTDAHGRQMEGHTHDISLGGLAVGTRLATPDMVGGEVTVRYDSARDGIHVGVPARVLDARDGTLRLRWAVRDLEDERQVVSMVFGRNDAWAGWADFAPDRPLRSLAMVFRSIGGLLRRRPAEAPRALHEMGEGELPATEEKLEKQSFVLKPVPRSARHGATASAALFVAFTALVPAAMAQEAPSPDQSGVTAETPFGDSNTGVVPDALPAIDPAVADRISDAEVTRTLTFRNLGATTGPLTLRGYSPLQGLDVVVPANRVVTHAQLTLSGALSPSLLPEANAVTVTLNEQYVGTLKVDPQHPQFGPVSFDIDPLYFTGDNKLNFHFAGEYRRDCNDLFNEILWARISDMSRITLTTVRITPERKLSRLPAPFFDPNQRSTLRVPVVLPATGDRGALRAAGLVASWFGRIADFRKLSFPVSTTIPASGNAVEVGVNLPVDAEGGRPAGPMLAEVANPNDRWGTVLVVTGRTAQEVEVAARALVFSPDTLGGVASKVVSDVSLETRHPYDAPAFVPTDRPVRFGELVGAADLQGGGFAPAGMTLPFHLPPDLYTWRGRPFLMNMWVRAPGGPVVDLETSRVDVSLNNNYLQSYTLSPPGLWRKWSERLVNQHAGAVGHVTALPPWLLFGQNQLQFNFDARPIDRGACRRTPGDIHMSVDSDSTLDFRRGYHFAEMPNLSYFAEAAFPFSRMADLSETTVVLPDHPDTGTTGAFLDLMGFFGASTWYPAAGVTVMGADEVAQTPPKGDIVVLGTAAQLGGAASGLLARSPYVIHDRHITVGQRMGLQGIWYLFQDHDHAGLKDGVTANLNAPIAEAGVLLAAQSPYDSQRSVVAFTGDTPERIHDLVLSLRNKGDLPSLQGDLVLKNGDRFTSYRTAPVYTVGSLPLWLRLDWFLGHHPSALYLAGLAGAGLAALGVWAWLRGWSRRRIARDDLTGEL
What are the official names of this protein?
Putative cellulose synthase 3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AcsB/BcsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: F16PA_XANAC
Sequence: MSRPSLTRFLIEEQHAGRIDAELRQLITIVSRACKRISIAVSKGALGGVLGDAGTGNVQGEAQKKLDVLSNDILLEANAWGGHLAACASEEMDHSQPVPDQYPSGDFLLLFDPLDGSSNIDVNVSVGTIFSVLRAPKGTEKPGDEHFLQPGTQQVAAGYCIYGPSTMLVLTLGHGTHAFTLEREEGSFLLTQANMRVPEDTAEYAINMSNQRHWEPAMQAYVGDLLAGKDGARGKDFNMRWIASMVADVHRILTRGGIFIYPWDKKDPSKPGKLRLMYEANPMSMLVEQAGGAATTGRERILDIQPTQLHQRVPVFLGSKNEVAEATRYHLDADKA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBJQ_SALHS
Sequence: MQFSTTPTLEGQSIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFQELGEQAKALGADAVVGIDIDYETVGKDGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: VF350_IIV3
Sequence: MSNGKIYQKIDLSNVDRKKIKDDHESVVVHNEIKHTKELWTFPRRSDWGTSGVRCYWDHHEFDGTPIYCPVSYRPRQVAKISKNEIKPTCRNQSIVDVSTFTIKENIPKSKDVSNLLEKDLIKITDPYYEVDGVFCSPECCVAWIRNEKTKAGGSMYSDSERLLHSMLGLVQKITPANNFRLLKSYGGNLTIDQFRKNNKCIKYEYYGTTVLISHLFEKKINLSSD
What are the official names of this protein?
Uncharacterized protein 026R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 350L family.
Protein: Y1939_STRTD
Sequence: MSHNHDHNHDHEVITLVDEQGNETLFEILLTIDGREEFGKNYVLLVPAGAEEDADGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFIDEN
What are the official names of this protein?
UPF0473 protein STER_1939.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: SEC4_CANAW
Sequence: MSGKGTSSRAYDMIMKLLLVGDSGVGKSCLLLRFVEDKFNPSFITTIGIDFKIRTIESKGKRIKLQVWDTAGQERFRTITTAYYRGAMGIVLIYDVTDSRSFENVENWFQTVTQHANEDAQIFLVGNKCDDEVNRQVSKEQGQELAAKLNVPFLEASAKSNENVDSIFYELASIIQEKHVEENIGGVGGASGAGGIDVSQNNSGAKNNCC
What is the function of this protein?
Involved in exocytosis.  Maybe by regulating the binding and fusion of secretory vesicles with the cell surface.  The GTP-bound form of SEC4 may interact with an effector, thereby stimulating its activity and leading to exocytotic fusion.  SEC4 may be an upstream activator of the 19. 5S SEC8/SEC15 particle.  SEC4 probably interacts directly with SEC8; it could serve as the attachment site for the SEC8/SEC15 particle (By similarity).
What are the official names of this protein?
Ras-related protein SEC4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Lipid-anchor; Cytoplasmic side. Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: LPQW_MYCS2
Sequence: MGVPTPARRARLTFGALLAVPTLLLGGCTVSPPPAPQSTETTETTPPPPPKAPTQIIMAIDSIGPGFNPHLLSDQSPVNAAIASLVLPSSFRPVPDPTSPTGSRWELDTTLLESAEVTNENPFTVTYKIRPEAQWTDNAPIAADDYWYLWRQMVSQPGVVDPAGYDLITGVQSVEGGKQAVVTFSQPYPAWRELFNDILPAHIVKDIPGGFGAGLARAMPVTGGQFRVETIDPQRDEILLARNDRFWSVPAKPDLVLFRRGGAPAALADSIRNGDTQVAQVHGGAATFAQLSAIPDVRTARIVTPRVMQLTLRAQQPKLADPQVRKAILGLIDVDLLASVGAGDDNTVTLAQAQVRSPSDPGYVPTAPPAMTRDDALELLRDAGYVSEPVPPPDNTADDPPPDNGRERIVKDGVPLTIVLGVASNDPTSVAVANTAADQLRNVGIDASVLALDPVALYGDALVNNRVDAVVGWRQAGGDLATVLASRYGCRALEATPVATAVPGPATTTSQAPTTTTTTTPPATTTPTPTAPIPAPESGELVQAPSNITGICDRSIQPRIDAALDGTDDIADVIQAVEPRLWNMATVLPILQDTTIVAAGPSVQNVSLTGAVPVGIVGDAGDWTKTK
What is the function of this protein?
May directly or indirectly regulate the accessibility of the key branch point intermediate, monoacyl phosphatidylinositol tetramannoside (AcPIM4), to the elongating alpha-1,6 mannosyltransferases which could regulate the lipoarabinomannans (LAMs) biosynthesis.
What are the official names of this protein?
Probable monoacyl phosphatidylinositol tetramannoside-binding protein LpqW.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
Protein: DRE2_PHANO
Sequence: MAAPRTLLLCPPSLSAHPEALNKIYEIHDRSTADLQMLDRIAAGLVQLPAATYDVVLLLTDADGTTRESHKLLARDVASKVAGALKVGGILKAKTEAILAGLSESPNGMVKTEQVESVSIPLKFGKKKTNGVNGTNGAVNPDGSVPLNLNGKRNQPEPVKPVGVGFVDFSDDLDDPIITGEDDDDDLIDEDDLITEEDMARPVIQQCRPKAGKRRRACKDCTCGLKEKMEAEDAAKRTTADKALNTMKLGADDLDELDFTVQGKVGSCGNCALGDAFRCDGCPYIGLPAFKPGEEVRLLNNDIQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: M4H32_BOMMX
Sequence: MNFKYIIAVSFFIASAYARRNEKDVQSLSQRDVLEEESLREIRGIGGVLLSAGKAALKGLAKVLAEKYANGKRTAEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTKKEKRILGPVLGLVGNALGGLIKKIG
What is the function of this protein?
Maximin-H3 shows antibacterial activity against both Gram-positive and Gram-negative bacteria.  It shows also antimicrobial activity against the fungus C. albicans.  Shows strong hemolytic activity.
What are the official names of this protein?
Maximins 4/H3 type 2.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CECA2_DROME
Sequence: MNFYNIFVFVALILAITIGQSEAGWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATARG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-A2.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HISZ_ACIB3
Sequence: MTISETWLLPDGVADVLPEQAQVIEKLRREAIDFLAVRGYQLVYTPFIEYIESLSSLSESNQDLDLVTFKVIDQLSGRLLGIRADMTPQVARIDAHVRPVEGVARYCYAGTVLHTKPQNFNATRAPLQLGAELYGHDSIEADVEMVDVMLGLIENAYTLQGAHLDLGHVGLFRSLVKYAGLSKNEEHELSDLYQRKALPELAEFTQNLNMGSDFYALGRYASDLDALQAHLSADILKDAEFDAALNALKTTLEQIKNRWPALNVGIDVVELRSYHYHTGLMYAVYAPNRAAPLAQGGRYDGIGEHFGRARPATGFSCDLYALGANQFAEIETVVAPKGTEADLLKAIANARSEGLRVVQLLGNDDLSSIPYATHQLVLQNGQWNIEKI
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAGG_ECOLI
Sequence: MTQLTMKDKIGYGLGDTACGFVWQATMFLLAYFYTDVFGLSAGIMGTLFLVSRVLDAVTDPLMGLLVDRTRTRHGQFRPFLLWGAIPFGIVCVLTFYTPDFSAQGKIIYACVTYILLTLVYTFVNVPYCAMPGVITADPKERHALQSWRFFLAAAGSLAISGIALPLVSIIGKGDEQVGYFGAMCVLGLSGVVLLYVCFFTTKERYTFEVQPGSSVAKDLKLLLGNSQWRIMCAFKMMATCSNVVRGGATLYFVKYVMDHPELATQFLLYGSLATMFGSLCSSRLLGRFDRVTAFKWIIVAYSLISLLIFVTPAEHIALIFALNILFLFVFNTTTPLQWLMASDVVDYEESRSGRRLDGLVFSTYLFSLKIGLAIGGAVVGWILAYVNYSASSSVQPVEVLTTIKILFCVVPVVLYAGMFIMLSLYKLTDARVEAISRQLIKHRAAQGEAVPDAATAASH
What are the official names of this protein?
Putative glycoside/cation symporter YagG.
What is the protein family that this protein belongs to?
Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELO_CERS4
Sequence: MTFRFDNSYARDLEGFYVDWPAAPVPAPRLLRLNRPLAEELGLDPDLLEREGAEIFSGRRLPEGAHPLAQAYAGHQFGGFSPQLGDGRALLIGEITDRAGRRRDLQLKGSGRTPFSRGADGKAALGPVLREYLVGEAMHGLGIPTTRALAAVATGEPLLRQEGERPGAILTRVAASHIRVGTFQFFAARSDIDRVRRLADYAIARHYPELASAPEPYLAFYEAVAEAQAQLVARWMLVGFIHGVMNTDNMTISGETIDYGPCAFMEGYDPGTVFSSIDLQGRYAYGNQPYILAWNLARLGEALLPLLDGDPVRAADKATSVLETVGARYQGHWLAGMRAKLGLAGAEEGDARLAEDLLEAMRSQRADWTLTFRRLAEAVTDEGALRPLFRDPAALAGWLPRWRARLAPDAAERMRATNPIYIARNHRVEEALAAAHAGDLAPFDRLLEALADPFTERADRELFALPAPEGFDDSYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RUVA_RHOE4
Sequence: MIASVRGEVLDIALDHAVIEASGVGYRVNATPVTLGALHRGSEARLFTTMIVREDSMTLYGFSDTESKDLFSLLQTVSGVGPRLAMATLAVLEPDALRRALSEGNLTALTRVPGIGKRGAERMVVELRDKVDAVATTAGAASGAVVGSSIRDQIVEALEGLGFPIKQAEQATDSVLAESPEATTSVALRSALSLLGKTR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MRAY_BIFLO
Sequence: MIALIIGMLVSLIVTLVGTPLLIRLVHKLHYGQYIRQDGPQSHLVKRGTPTLGGVVINFAILLGWASSALYRYLRSGDVPSWSAALVLFAMLSMGLLGFIDDFAKVRKKQNEGLSVGGKFIGQFIFATIYAVLALLIPTKSGFPSAQAGISFIEQPFFNFDFAGRAVAIILFVIWVNFLMTAWTNAVNLTDGLDGLAAGSSMIAFTGFGIIAFWESYHIKGGSHGGYSYAVSDPLDLTVIAVCAAVACFGFLWYNSNPASIFMGDTGSLALGGLFAALSIATHTEFLAVVLGGLYVMEAMSDVIQVGYFKMTHKRVFKMAPIHHHFELEGWTETKVVVRFWMIELIFVLLALTIFYGDWVTRSGLLFS
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS8_THEP3
Sequence: MVMTDPIADMLTRIRNANIARHETVEIPASNMKRAIAMIMLKEGFIKSVEEIDDGKGGILKLTLKYGPNKERVISGLKRISKPGLRVYARHDELPRVLGGLGIAIISTSKGIMTDKEARKAGVGGEVICYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SYGB_PASMU
Sequence: MTTQNFLAEIGTEELPPKALKKLATAFAENMELELNQAGLAFESVQWFAAPRRLAVKVLALATSQPSKEIEKRGPAVSAAFDAEGKPTKAAEGWARGCGISVEQAERVATDKGEWLVHRATIEGQPTKNLLKDMVANALAKLPIPKPMRWADKTVQFIRPVHTVTMLLGDELIEGEILGVESARTLRGHRFLGEREFQISHADQYPALLKEKGSVVADFNDRKALILAKSQEKATALGGVADIEDDLLDEVTSLVEYPNVLAAKFEERFLAVPAEALVYTMKGDQKYFPIYDKDGKLLPHFIFVSNINPDDPSKIIEGNEKVVRPRLTDAEFFFKTDLKQRLEDQLPRLETVLFQQQLGTLRDKTARIEQLAGEIAKQIGADEVKAKRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEDEEVAVALNEQYMPRFAGDELPKSLVASAVALADKFDTLTGIFGIGQQPKGSADPFALRRAALGALRIIVEKNLPLDLAEIVKKSSALFGDKLTNANVVEDVVEFMLGRFRAWYQDEGIAVDVIQAVLARRPTKPSDFDARVRAVSHFRALEAAEALAAANKRVSNILAKVEGELPANIDTTLCAEAAEKVLAEQVIALQAELAPLFAKGEYQVALDRLAALREPVDTFFDNVMVNAENPQLRQNRLAILNNLRNLFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPI3_SOLTU
Sequence: YNIGNLQCPNAVLQHMSIPQFLGEGKPVVFVRKSESDYGDVVRVMTVVYIKFFVKTTKLCVDQTVWKVNDEQLVVTGGKVGNENDIFKIMKTDLVTPGGSKYVYKLLHCPSHLGCKNIGGNFKNGYPRLVTVDDDKDFIPFVFIKA
What is the function of this protein?
Inhibitor of cysteine proteases.  May protect the plant by inhibiting proteases of invading organisms.
What are the official names of this protein?
Cysteine protease inhibitor 3, PCPI-3, Pcpi3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Vacuole.
Protein: PRAM9_HUMAN
Sequence: MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation (PubMed:26138980).  The CRL2(PRAMEF9) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding (PubMed:26138980).
What are the official names of this protein?
PRAME family member 9.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
Protein: PTH_HELPJ
Sequence: MTLLVGLGNPTLRYDHTRHNAGFDILDSLVSELDLSFIFSPKHNAYLCVYKDFILLKPQTYMNLSGESVLSAKNFYKTKELLIVHDDLDLPLGVVKFKKGGGNGGHNGLKSIDALCSNSYYRLRVGISKGINITEHVLSKFHNNEEPLKNAAFEHAKNALKFFIESHDFNATQNRFTLKKPLQIES
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_STRPG
Sequence: MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELEIPILGICYGMQLITHKLGGKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSNDCPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RLMH_CLOK1
Sequence: MNITIIAVGKLKEKYLKAAVEEYSKRLSRYCRLNIIEVQDEKTPDNASSSEQDIIKEKEGRRILKYINDNMYVVALDLKGSMMGSEEFSKFVGNLGLSGKSNIAFIIGGSLGISSEILKRADYKLCFSKMTFPHQLFRIMLLEQIYRGFRIMKGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VTCN1_MOUSE
Sequence: MASLGQIIFWSIINIIIILAGAIALIIGFGISGKHFITVTTFTSAGNIGEDGTLSCTFEPDIKLNGIVIQWLKEGIKGLVHEFKEGKDDLSQQHEMFRGRTAVFADQVVVGNASLRLKNVQLTDAGTYTCYIRTSKGKGNANLEYKTGAFSMPEINVDYNASSESLRCEAPRWFPQPTVAWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKVTDSEVKRRSQLQLLNSGPSPCVFSSAFVAGWALLSLSCCLMLR
What is the function of this protein?
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity.  When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity.  Involved in promoting epithelial cell transformation.
What are the official names of this protein?
V-set domain containing T-cell activation inhibitor 1, B7 homolog 4, B7-H4, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. BTN/MOG family.
What are the subcellular locations of this protein?
Cell membrane; Lipid- anchor, GPI-anchor. Note=Expressed at the cell surface. A soluble form has also been detected.
Protein: ALL21_GLYDO
Sequence: GKMNFTDCGHNEIKELSVSNCTGNYCVIHRGKPLTLDAKFDANQDTASVGLVLTAIIDGDIAIDIPGLETNACKLMKCPIRKGEHQELIYNIGEIPDATPEIKAKVKAQLIGEHGVLACGWVDGEVQE
What are the official names of this protein?
Mite group 2 allergen Gly d 2.01.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RDRP_I43A0
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSERGRWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCIETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNVTKKMVTQRTIGKRKQRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISFTITGDNTKWNENQNPRMFLAMITYMTRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNDSTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLLGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFEIKKLWEQTRSKAGLLVSDGGPNLFNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVMMPAHGPAKNMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQRCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFTEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.