PharMolix/UniProtQA huggingface dataset:
Protein: PSD1_MOUSE
Sequence: MAQGAMRFCSEGDCAISPPRCPRRWLPEGPVPQSPPASMYGSTGSLIRRVVGPGPRGRDLGRVTAPCTPLRAPPSPHIAPSPWGPSSPTGQPPPGAQSSVVIFRFVEKASVRPLNGLPASGGLSRSWDLGGISAPRPTPALGPGCNRKLRLEASTSDPLPAGGGSVLPGSRDPSRGPLVPPQIGADGLYSSLPNGLGGTPEHLAMHFRGPADTGFLNQGDTWSSPREVSSHAQRIARAKWEFFYGSLDAPSSGAKPPEQVLPSRGVGSKQGSGVAVGRAAKYSETDLDKVPLRCYRETDIDEVLAEREEADSAIESQPSSEGPHGTAQPPASRPSPCPGPSSSLGSGNEDDEAGGEEDVDDEVFEASEGARPGDHMPHSGLLKSPVPFLLGTSPSADGPDSFSCVFEAILESHRAKGTSYSSLASLEALASPGPTQSPFFTFEMPPQPPAPRPDPPAPAPLAPLEPDSGTSSAADGPWTQRREVEESDAGATLAPRKELPSPSHSEDSFGLGAAPLGSEPPLSQLVSDSDSELDSTERLALGSTDTLSNGQKADLEAAQRLAKRLYRLDGFRKADVARHLGKNNDFSKLVAGEYLKFFVFTGMTLDQALRVFLKELALMGETQERERVLAHFSQRYFQCNPEALSSEDGAHTLTCALMLLNTDLHGHNIGKRMTCGDFIGNLEGLNDGGDFPRELLKALYSSIKNEKLQWAIDEEELRRSLSELADPNPKVIKRVSGGSGSSSSPFLDLTPEPGAAVYKHGALVRKVHADPDCRKTPRGKRGWKSFHGILKGMILYLQKEEYQPGKALSEAELKNAISIHHALATRASDYSKRPHVFYLRTADWRVFLFQAPSLEQMQSWITRINVVAAMFSAPPFPAAVSSQKKFSRPLLPSAATRLSQEEQVRTHEAKLKAMASELREHRAAHLGKKARGKEADEQRQKEAYLEFEKSRYGTYAALLRVKMKAASEELDTIEAALAQAGSTEDGCPPPHSSPSLRPKPTSQPRAQRPGSETRAGAGSTRPKP
What is the function of this protein?
Guanine nucleotide exchange factor for ARF6 (By similarity).  Isoform 2 and isoform 3 induce cytoskeletal remodeling, but lead to distinct morphological changes in HeLa cells: isoform 2 induces cell elongation and formation of actin-rich protrusions, whereas isoform 3 promotes the formation of membrane ruffles and loss of stress fibers (PubMed:19494129).
What are the official names of this protein?
PH and SEC7 domain-containing protein 1, Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6, Exchange factor for ARF6, Exchange factor for ARF6 A, Pleckstrin homology and SEC7 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PSD family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane. Cell projection, ruffle. Note=Colocalizes with ACTN1 in membrane ruffles and central reticular structures. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane. Cell projection. Note=Accumulates in microvilli-like protrusions. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane. Cell projection, ruffle. Note=Colocalizes with F-actin in membrane ruffles. SUBCELLULAR LOCATION: Cell membrane. Cell projection, ruffle membrane. Cleavage furrow. Note=Distributed uniformly on the plasma membrane, as well as throughout the cytoplasm during metaphase. Subsequently concentrated at patches in the equatorial region at the onset of cytokinesis, and becomes distributed in the equatorial region concurrent with cleavage furrow ingression. In later cytokinesis phases, fades away from the cleavage furrow and becomes uniformly distributed throughout the plasma membrane.
Protein: YOMX_BACSU
Sequence: MKDYSNYHKVNINNKLLHDGKLIFQQGLKGFESEKVTIDGIEKTVMITSKYSSGDGSARYILGEIADIYRGGVVKFNDETWLITSHPLSNKIYKKAEIKICGTSFFLTSEDKLIDTGKINEITGKPIYEKVPGEKTEVPCIFERTTSINGTELAVNLPDGQANITIPYLVHEKLKIGLTLTFFGEDYQVDDIDYSKVYGDHGTIKLVAKKKVGEKT
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YomX.
Protein: EST4A_BOVIN
Sequence: MNWILCLSLTLLLVVQTAWGALHTKEPLADTKYGTLRGKQIHVGKTPINVFLGVPFSKPPVGAHRFAAPEPPEPWEGIRDATTYAPVCLQESWGQVTSMYFNTHKRYKWLHFSEDCLYLNVHAPVRARGDPLQPVMIWFPGGAFLVGSASTYDGSELAAREKVVVVVLQHRLGILGFLSTGDSQARGNWALLDQIAALRWVQKNIEAFGGDPGCVTLFGQSSGAMCISGLMTSSLARGLFHRAISQSGTAVFQNFITPDPLKVAKKIAQLAGCNHNSTKILVDCLRTLSGAEVMRVSQKMRFFKLHSQEDPQKVVWFMSPVVDGVVFQDNPIVLLTQGQVAPVPYLLGVNNLEFNWLLPFIMKFPMSHLRKETIAKLLWSTSTLLNVTKEQLPLVMEEYLRDVDDHDQKMLQKHVMDLAADATFVYSTLQAAHYHHNAGFPVYLYEFEHYAPGTIVKPRTDGADHGDEIGFIFGSPFSKGHSSNKEKALSLQMMKYWANFARTGNPNGGKLPYWPRYNKDEKYLQLDLTTRVGVMLREEKMAFWKRLHQN
What is the function of this protein?
Probable carboxylesterase.
What are the official names of this protein?
Carboxylesterase 4A.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: COFH_TRIV2
Sequence: MNYKTVDVILERALLGDDISPQEGIVLLTQTDSGAIASIRHTADKLRQQQAGDTVTYVINRNINFTNICEQHCSFCAFRRNDGDADAYWLDWAGILEKSHDAVQRGATEICMQGGLHPQAQIDGKSLPYYLKLLETIKQEYPQIHLHAFSPQEVQFIARMDGLEYAGVISALQNAGVNSLPGTAAEVLDDQVRRVLCPEKINTATWLEIISTAHKLGLHTTSTILSGHIETPEQQIGHLEKLRSLQQIATNQKYPARITEFIVLPFVGQEAPKSLRRRVGRDQPVLADALLLGAVARIYLGNWIANHQPSWVKLGLAGATEALNWGCNDIGGTLMEEHITTMAGAVGGTCMEVETLQNAIASIGRPYQQRDTLYQPVESAKQLANTVIGNG
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: AMPP2_CHAGB
Sequence: MEFCDESYDLVNIDEFDALWVASRHGVAFGVPPCLLISDDDAIARSSIELKSGPSSSNLSPSTLSTEKTSSDSSGVICDPQLHETWREGLGKFPAKEHARKVARELGADHGIIFLLGQDEKYYEDSDMGPTFRQRRYFYYITGADFPGCAVTYDILRDKLVLWIPRIEPRTVLWFGKVPTPEECKAASDVDSVYYIDFLHEKQCPVFKRGQTIHVLHPDQIPPELDHLGKFIRIDAVRLKPAMDAARVIKTDYEIALIRRANAVSSAAHKAVLRNIKRFTNEREIDALFRGYCIAHGAPIQSYPVIAASGINASTLHYDDNNQSLKNRQLLILDAGAEVHCYASDITRTIPLPGSFTPLAREIYRLVERMQDECIAQIKPGVRFSALHAHACAVAVTGLLKLGILRGEEEEILARGTVAAFFPHGLGHHVGLEVHDVSGTERLLLNGGPGSGPGSGGGYGCGASTWRGYRLRRRVMTKRESLTPWEVAALWEGAKPEKEKQQERWLLNNVPLDEVEAALTLASSSGARGQKLAPGMVVTVEPGIYFLPRVLEKYWNVGGVRIEDDILVTKKGYENLTTAPKGDEMMKCMGESGLL
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase CHGG_02942, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: A18_YLDV
Sequence: MSVCTEIDYKLYTELKKIAGNSLFLFNENGDFTEVVLNSSFKFLVPIGFFSSIDIPLKKPIEYKNNNNNIEHSKNIILPNLYPFQKHVVSEVLLSMEKKNKHKRPTYITLHLACGFGKTITSCYLLSLHKKKAVICLPNKMLINQWKRAIESINMDHIVSVDGVSNLLKEMVKKTADILIIVSRHLLNEEFCKKIYLNYDIFILDESHMYNLMNNSAVTKFLTYYPPKVCYFLTATPRKVNRIYCNDIINVSNSLELKKYIKIVEFFFETYSSDTIKQMVKKLNTNYNKYHMYTEKILAEDVPRNELILDTIIYDFNKMLINRLIIVTKLRKHMMFFYDRLSEKFGLDVVYLGDAKNKNISDIVKKIKSIDRFIFISTTNYSGTGLDVPTLDSLVICSAVMNSMQIEQILGRICRSSVSKTRTVIVFPNTSIKEIKHMVGFFTQKIITLAIEKLNFKKIEKKGKKKELALCKAFNLQTH
What is the function of this protein?
DNA helicase which seems to act as a postreplicative transcription termination factor.  Involved in ATP-dependent release of nascent RNA.  Forms a stable complex with single-stranded DNA, and to a lesser extent RNA (By similarity).
What are the official names of this protein?
Transcript termination protein A18.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Poxviruses subfamily.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: PR15B_HUMAN
Sequence: MEPGTGGSRKRLGPRAGFRFWPPFFPRRSQAGSSKFPTPLGPENSGNPTLLSSAQPETRVSYWTKLLSQLLAPLPGLLQKVLIWSQLFGGMFPTRWLDFAGVYSALRALKGREKPAAPTAQKSLSSLQLDSSDPSVTSPLDWLEEGIHWQYSPPDLKLELKAKGSALDPAAQAFLLEQQLWGVELLPSSLQSRLYSNRELGSSPSGPLNIQRIDNFSVVSYLLNPSYLDCFPRLEVSYQNSDGNSEVVGFQTLTPESSCLREDHCHPQPLSAELIPASWQGCPPLSTEGLPEIHHLRMKRLEFLQQANKGQDLPTPDQDNGYHSLEEEHSLLRMDPKHCRDNPTQFVPAAGDIPGNTQESTEEKIELLTTEVPLALEEESPSEGCPSSEIPMEKEPGEGRISVVDYSYLEGDLPISARPACSNKLIDYILGGASSDLETSSDPEGEDWDEEAEDDGFDSDSSLSDSDLEQDPEGLHLWNSFCSVDPYNPQNFTATIQTAARIVPEEPSDSEKDLSGKSDLENSSQSGSLPETPEHSSGEEDDWESSADEAESLKLWNSFCNSDDPYNPLNFKAPFQTSGENEKGCRDSKTPSESIVAISECHTLLSCKVQLLGSQESECPDSVQRDVLSGGRHTHVKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEDAIGYCLTFEHRERMFNRLQGTCFKGLNVLKQC
What is the function of this protein?
Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 15B.
What is the protein family that this protein belongs to?
Belongs to the PPP1R15 family.
Protein: HIS1_BURA4
Sequence: MTAPLTLALSKGRIFEETLPLLAAAGVQVAEDPETSRKLILPTTDPNLRVIIVRASDVPTYVEYGAADFGVAGKDVLVEHGGSGLYQPIDLNIARCRMSVAVPAGFDYANAVRQGARLRVATKYVETAREHFAAKGVHVDLIKLYGSMELAPLVGLADAIVDLVSSGGTLKANNLVEVEEIMAISSRLVVNQAALKLKRAALKPILDAFERASQNGN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_FRATU
Sequence: MSKQEKSNVEDKSLDIETAAQVETAQESASGALEELSVEEQLERAKDTIKELEDSCDQFKDEALRAKAEMENIRKRAERDVSNARKFGIEKFAKELLPVIDSIEQALKHEVKLEEAIAMKEGIELTAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIPNPEFEDNTIFDVFQKGYMLNGRIVRAAKVVIVKN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHC2_CORU7
Sequence: MHSWSAPRVPQFPSSIPAVADSPAAEVAALPELRLYDTADDRVKAVALPDDGAPVGIYVCGITPYDSTHLGHAATYNTFDLVNRYLRAAGHGVTYVQNVTDVDDPLFERADRDGVDWRELGKEQTDLFRSDMTQLRILPPEFFVGAMETIDEVVEMVSTLLDKGAAYVVDGEYPDIYADHTYTEQFGYESRYDEATMRELFAERGGDPEREGKRHPLDALLWRAHRTGEPEWDAPFGSGRPGWHVECAAIATNRLGEQFAIQGGGVDLRYPHHEYSAAHAEAACGNQRMAGHYVHTGMIGLEGTKMSKSLGNLEFVSALTAQGFDPAAIRVGLYAGHYREDRDWSAEVLNEAEDRLAKWRAAAAEENNPQRVAEVLATVTGHLANDLDTPSVLRTLDEWAAAVNESIGASGYQVTPAADRTAASQALTAGLDALLGVSV
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2, L-Cys:GlcN-Ins ligase 2, Mycothiol ligase 2, MSH ligase 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: YGAC_SHIFL
Sequence: MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARMGRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVALERYLNGLFGEAS
What are the official names of this protein?
Uncharacterized protein YgaC.
Protein: CYF_PSINU
Sequence: MQNRNKNNWMKKWVIRSISILIILNIIAWPSISYAYPIFAQQSYENPREATGRIVCANCHLAKKPVDIEVPQSVFPNTVFEAVVKIPYDKQIKQVLGNGKKGGINVGAVLILPEGFELAPYNRIPAEMKDKIGDLALFQNYRPDKRNIIVIGPVPGKAYSEIVFPLISPDPATNKEVHFLKYPIYLGGNRGRGQIYPDGSKSNNTIYNASIAGKVTKILRREKGGYEITIEDTLEGRRVVDIVPPGPELIISEGEFIKIDQPLTNNPNLGGFGQGDTEIVLQNPLRIQGLLLFFVSVIMAQILLVLKKKQFEKVQLAEMNL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: EMI1A_DANRE
Sequence: MALYFVYLSTLLALILLGDNWAAGTYASRYTQHVDENQSGAAAQSGSKVTSRHRNWCAYVVTRTVSCVMEDGVETYVKPEYQRCAWGQCSHVVLYRTYRKPRYKVAYKVVSEMEWKCCHGYSGDDCSDGSSAIHDSRARPTGEEGRSDSDRIRQLEEQIQSLNKNLHNLQKKIYEESQREGISGGNNLADAAQPGMKETIHSIQTKLDMLDNMTRVHDKTLTNINNHLVGGNGIENELDSRYGTLKEEILRELERRVTLSCSSCQTGVESIQRQHQEDRERIRELEKHISVMEQHHQQTLDLLSRSQSCCDSLDRKLSAIDRKVSSTAETYDILRGRLEKELRSNGNGGRGKAMEEKLNNRLRDLERRLNGTVRKTEQKCSHTETSMKEFVQREIGQIKNSVLGRNDDHGYRISTVEIDIQDLKRFINDHKNNLERLGNKTNDLDSGLKSAIHLCTETCAAKGSETEDTVKSLEWKVVANEEDIKKFDTKLKDISVSGDSLLDRVIDLSNDVQKIKDLTGQNGEHFNQIVTDVENLGRDCDVCSSIDGELQKIRNVTSYAFDKFQAELTVLGRKVFSDEHVCSQVCSNLQEEVGKLKEEVEKCTGQCMISMADHQRNVDNQNTVTRKLGKDLKSIQGELTGILQIFNSINDTLKGLRNTIQKHGNNITDLNTSKGKIYLELDQLYDDLNKHKVDSKGHFDSISSFNSNLMTEMGECRLSREGLDKRLSKMEDVCGRLDTLSENLKTIKDGLSKHVSGLWTCVNDLNSTVISHSETISRIHNVHLENIQGRMNNLNSSIRNVLKEFQIFTEQDFTGPPGLPGPQGEKGSKGPPGPRGPLGKEGPQGRVGPVGPPGLRGEQGPPGKDANVPRLSFSAALTRPQASSGTIIFNKVFINERKAYNPKTGVFTAPVRGRYFFSAVLTGHKNVKIEAVLSKSNFGIARGDSAGYQPEGLEKPMAEARHTPGSLVIFNIVLPLQEGDTICIDLVTGKLAHSVEPLTIFSGMLLYEESEDRL
What is the function of this protein?
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly.  Has cell adhesive capacity.
What are the official names of this protein?
EMILIN-1-A, Elastin microfibril interfacer 1a.
Protein: Y2377_PECAS
Sequence: MIAGMPALTHKQQQDAVERIQELMSEGMSSGQAIALVAAEIRENHTGGNVAMMFDDDDMINDSDDEYHFDDGEEEEEQ
What are the official names of this protein?
UPF0181 protein ECA2377.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: CYB_LEPBR
Sequence: MTNIRKTHPLLKIVNHSLIDLPAPSNISAWWNFGSLLGLCLLIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICLYMHVGRGIYYGSYTYLETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMIHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDLLGFLSLILLLLLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIIPLLHMSKQRSMMFRPVSQALFWVLVADLLTLTWIGGQPVEHPFITIGQVASVLYFSIILILMPLASLIENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NSS_CCHFI
Sequence: MLSALALSTSSLCLSRYPLRASTVFLASSNIPFPSVSASLARPVATSAIPERPDLLMSPHGGLKAMMYLPLTNSLHQSTCSWLTGPRGFSSPPLFRIRFLLLIMSDSISLTDITISPGTLYSARTLLLRAAVLALTRKPMSFLHFKAACW
What is the function of this protein?
Disrupts the host mitochondrial membrane potential and induces apoptosis probably by inducing host CASP8 and CASP9.
What are the official names of this protein?
Non-structural protein, NSs.
Protein: PUR9_SALSV
Sequence: MQQRRPVRRALLSVSDKAGIIEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEQHHIAPIDMVVVNLYPFAETVARVGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDANEGSLTLDTRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATAQQVQGKALSYNNIADTDAALECVKEFNEPACVIVKHANPCGVAVSTSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWASRVPGLDFKRVNGGLLVQDRDLGMVSEAELRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYAKENMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSAMASDAFFPFRDGIDAAAAVGVSCVIQPGGSIRDDEVIAAADEHGIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: XYLA_BRUA4
Sequence: MSTGFFGDIQKVKYEGPDSDSPLAFRHYNPDEIVLGKRMEDHLRFAVAYWHSFAWEGGDPFGGRTFDRPWYSNELDAAKLKADVAFEFFSLLGAPYYCFHDADVRPEGRNFAENTRYLNEIVDIFEKKQAETGVKLLWGTANLFSNRRYMGGAATNPDPDVFAFAAATVKSCIDATKRLGGENYVLWGGREGYETLLNTDLGRELDQMGRFLNLVVEYKHKIGFKGTILIEPKPQEPTKHQYDYDVATVYGFLKRYGLESEVKVNIEQGHAILAGHSFEHELALARALGIFGSIDMNRNDYQSGWDTDQFPNNVPEMALAYYQVLLAGGFTTGGTNFDAKLRRQSLDPQDLLIGHIGGMDCCARGLKAAAAMLEDGALSKPLDERYAGWNGDFGKKLLTGLSLDQITAEVETKDINPQPKSGRQEYLENVVNRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED9_ASHGO
Sequence: MSAQASPATELQNPTLGQVYATLTRHSAQQTEFIPHIFYALHQLKNDNGHTNTFETATSNIRHRLKLCKAAIAGDAHAVEMLSRPCDEWPAVVCQKEQEIEAKKRVHRQLRQRVEEIAGPLDAAAAP
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 9, Mediator complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 9 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AL1A2_MOUSE
Sequence: MTSSEIAMPGEVKADPAALMASLQLLPSPTPNLEIKYTKIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKVLELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS
What is the function of this protein?
Converts retinaldehyde to retinoic acid (PubMed:8797830).  Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal (By similarity).  Lacks activity with benzaldehyde, acetaldehyde and octanal (PubMed:8797830).  Displays complete lack of activity with citral (By similarity).
What are the official names of this protein?
Retinal dehydrogenase 2, RALDH 2, RalDH2, Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, RALDH(II).
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_RUBXD
Sequence: MIVFATILFGALSAEDPDVEKLDSQEFQRAVEERAFALGPEDHAPAGGEGQGAAGHRELRHPVGRAPSGGAGSDLEPGPLKVYDESQKVTGLLKPEGGGEPREFEYSYPEGYDIARVLNEANIPFTTDPQTAGPWARAIAVMAPFVLILLLFFLMTRTGRSASQSSRMTDFGKSRARRMTKDQPKVTFADVAGADEAVQELTEIKEFLENPQKFQKLGARIPKGALLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDSKSGIIMLAATNRPDILDPALLRPGRFDRQIVVDRPDLPGRIKILKVHTRGKPLGEDVDIETIARGTPGFTGADLANLVNEAALLAARHNKEQIEMAEMEEAIDRVIAGPERKTRLISEKEKEITAYHEAGHAIVGALLPEADPVHKVTIIPRGQALGVTMSLPEEDRFMMSRAQLMAQLSYMLGGRAAERVVFEEITTGASNDIERATKVARQMVTRYGMSEKLGLIALGQHDGQVFMGRDLHAQPDYSDEIAFQIDKEIRRLVDEAYDTAEDLLVRNRRLLEKLASDLIEYETVDAEHLRRLVEEYAVDEHPSRGRPAMSVNGHRG
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: ACDH1_NOCSJ
Sequence: MTRTKVAIIGSGNIGTDLMIKVLRTSKHLEMGAMVGIDPASDGLARAGRFGVPTTAEGVEGLVALPGFDDIEIVFDATSAGAHVVNAARLLPLGKRLIDLTPAALGPFTIPAVNLEDHLEAPNLNMVTCGGQATIPIVAAISRVVPVEYAEIVASIASRSAGPGTRANIDEFTETTSSAIVEVGGATRGKAIIILNPAEPPLIMRDTVFALVTAADPDVHEQIRASVDKMVADVAAYVPGYRLKQAVQVTEIPADQPVHTLLAPDAERPTHQVSVFLEVEGAAHYLPAYAGNLDIMTSAALQVAERIAAGKADR
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RS10_SYNC1
Sequence: MQSQKIRIRLKAYDHKLLDLSVNEIVDTAKRTGARVAGPIPLPTIINKYCVLRGPHVDKKSREQFEMRTHKRLLDIVEPTQQTVDALMKLDLSAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RPOZ_SYNJB
Sequence: MASRKNQLAIDNDELMRRVEALINASKNRYRITVQVANRAKRRRYEDPDDIEDGWMKPIRRAVIEMSDELTEPEIIGDE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: DEF_CYTH3
Sequence: MIYPIVAYGDPVLKKVAQDIEKGSLDVVKMSADMFETMENAHGVGLAAPQVALNLRMFVIDTSVFDDEKITPVRKTFINPVIEEEWGDEWPYEEGCLSIPGVRADVYRPANLRIRYFDTDWKEHVEEFDGMTARVIQHEYDHIEGVLFVDHLSSIKKRLLKGKLTNISKGDCDASYRMKFPIKK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: COAA_SHESR
Sequence: MTSKNPIQKALYLAFERTQWSVLRDAVPMTLSEQDLENLRGINEKVSLTEVTDIYLPLSRLLNLIVKAKQQRGLVLDEFLGQKPSSSPYIISIAGSVAVGKSTTARILQALLRHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFIAAVKSGQAHVNAPIYSHVTYDRIRGQHQTVSQPDILILEGLNVLQTGLDSPVDIRRPFVSDFVDFSIYVDAEEHLLKQWYQERFLQFRKGAFSDEKSYFHHYASLTDDEANVIAAKIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDA_SALEP
Sequence: MSSWVEVSLNTPAQLSLPLYLPDDETFASFWPGDNASLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECVAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDHASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: RL21_LEPBJ
Sequence: MYAIISVGNRQYKVTQDQEFLTEKTGKNAGESFDAKVLLFAESSNKVHIGQPELKTARVSLKVLEDVKGDKIHAYVYKRRKNYQKAWGHRQKLQKVKVVSLSAV
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.