PharMolix/UniProtQA huggingface dataset:
Protein: FPG_CAUSK
Sequence: MPELPEVETVRRGLEPVLSGARLARVRANRPDLRFPLPDGFVQRLTGAKILRLDRRAKYLLVPLDRGDTLVMHLGMTGRFEIAAPSGTIRPGDFAREVTPDDKHAHVVFETEDGAVVTYYDPRRFGFMDLIATDKVDRHPWFAAMGPEPLGEGFDAKTLVAAFNGRKQGPKTLLLDQKTVAGLGNIYVCEALHRAHISPFKPAGMIAGKRLGPLTTAIKDVLAEAVEVGGSSLKDFAATDGALGYFQHRFRVYDREGQPCPTPGCKGMIGREVQAGRSTFFCPVCQV
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: GPMI_PSEPG
Sequence: MTSTPKPLVLIILDGFGHSEVPEHNAIFAANTPVYDRLRATLPHGLISGSGMDVGLPDGQMGNSEVGHMNLGAGRVVYQDFTRVTKAIRDGEFFKNPVLTGAVDKAASAGKAVHILGLLSDGGVHSHQDHLVAMAELAAQRGAEKIYLHAFLDGRDTPPRSAQSSIELLDATFAKLGKGRIASLIGRYYAMDRDNRWDRVSAAYNLIVDSAAEYTADTAQAGLEAAYARDESDEFVKATRIGEAVKVEDGDAVVFMNFRADRARELSRAFVEPDFTEFARARLPKMAAYIGLTQYSAKIPAPAAFAPSSLNNVLGEYLAKNGKTQLRIAETEKYAHVTFFFSGGREEPFEGEERILIPSPKVATYDLQPEMNAPQVTDRIVEAIEQQRFDVIVVNYANGDMVGHTGVFEAAVKAVEALDTCVGRIVDALEKVGGEALITADHGNVEQMEDECTGQAHTAHTTEPVPFIYVGKRNLKVRDGGVLADVAPTMLQLLGLEKPVEMTGTSILVDA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: PLY2_PECAS
Sequence: MKYLLPTAATGLLLLAAQPAVAANTGGYATTDGGETSGAVKKTARSLQEIVDIIEAAKVDSKGKKVKGGAYPLIITYNGNEDSLIKAAEKNICGQWSKDARGVQIKEFTKGITILGTNGSSANFGVWIVNSSDVVVRNMRFGYMPGGAQDGDAIRVDNSPNVWIDHNEIFAKNFECKGTPDNDTTFESAVDIKKGSTNVTVSYNYIHGIKKVGLSGASNTDTGRNLTYHHNIYRDVNSRLPLQRGGLVHAYNNLYDGITGSGFNVRQKGIALIESNWFENALNPVTARNDSSNFGTWELRNNNVTKPADFSKYNITWGRPSTPHVNADDWKNTGKFPSISYKYSPVSAQCVKDKLANYAGVSKNLAVLTAANCK
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.
What are the official names of this protein?
Pectate lyase 2, Pectate lyase B, PLB, Pectate lyase II, PEL II.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family. PLADES subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL27_BORBU
Sequence: MATSKSGGSSKNGRDSISKRLGVKRSGGQFVKAGEIIVRQRGTKFHKGKNVGLGRDYTIFALSSGKVEFKTLKGRKYVSIV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RL33_CHLAA
Sequence: MASKKGNRIVIKLKSTESGHTYTTEKNRRNDPSRLELRKYDPIVRRHVLYRETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SNR25_BOVIN
Sequence: MVVQDPLLCDLPIQVTLEEVNSQIALEYGQAMTVRVCKMDGEVMPVVVVQNATVLDLKKAIQRYVQLRQEREGGIQHISWSYVWRTYHLTSAGEKLTEDRKKLRDYGIRNRDEVSFIKKLRQK
What are the official names of this protein?
U11/U12 small nuclear ribonucleoprotein 25 kDa protein, U11/U12 snRNP 25 kDa protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCSH_HALS3
Sequence: MSFDVPDDLQYLESHEWIDPATGRVGISEFAQDELGDVVFVELPSVGDALDQHDELGVVESIKAVSDLYAPVSGEVTAVNDALTNEPELVNEAPFGDGWLVEIDFDSDDLEATLDSDDYRAQIA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Probable glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RL34_BRUA4
Sequence: MKRTYQPSKIVRKRRHGFRARMATTGGRKVLTARRSRGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NA122_ANTEL
Sequence: GVPCLCDSDGPNVRGNTLSGILWLAGCPSGWHNCKAHGPTIGWCCKQ
What is the function of this protein?
Modifies current passing through the fast sodium channel (Nav) in neuroblastoma cells, leading to delayed and incomplete inactivation.  Produces a positive inotropic effect in mammalian heart muscle (By similarity).  Paralyzes the shore crab (C. maenas) by tetanic contractions after intramuscular injection.
What are the official names of this protein?
Delta-actitoxin-Ael1d, Delta-AITX-Ael1d, Toxin APE 2-2.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COBH_PSEAE
Sequence: MIDYIRDGQAIYRQSFATIRAEANLAGIPADLEKLAVRVIHACGMVDVVDDLRFSPGAGAAGRAALAAGAAILCDARMVAEGVTRSRLPAANRVICTLNEADVPALATELGNTRSAVALEHWREHLEGSVVVIGNAPTALFYLLEMLDAGAPKPALILGFPVGFVGAAESKEMLAADSRGVPYVIVRGRRGGSAMAAAAVNALATERE
What is the function of this protein?
Catalyzes the conversion of precorrin-8X to hydrogenobyrinate.
What are the official names of this protein?
Precorrin-8X methylmutase, HBA synthase, Precorrin isomerase.
What is the protein family that this protein belongs to?
Belongs to the CobH/CbiC family.
Protein: ATPB_CHLL2
Sequence: MQEGKISQIIGPVVDVDFPEGQLPSILDALYIVRPDGSRLVLETQQHLGEERVRTVAMESTDGLVRGLSVVNTGKSIQVPVGSEVLGRMLNVVGEPIDGKGAVNTKKTYSIHRSAPKFEDLSTKAEMFETGIKVIDLLEPYSRGGKTGLFGGAGVGKTVLIMELINNIAKQQSGFSVFAGVGERTREGNDLYHEMMESGVIEKTALVFGQMNEPPGARQRVALTGLSIAEYFRDEENRDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGELQDRITSTKNGSVTSVQAIYVPADDLTDPAPATAFAHLDATTVLSRSIAELGIYPAVDPLDSTSRILDPNIVGDDHYNTAQAVKQILQRYKDLQDIIAILGMDELSDEDKLVVSRARKVQRFLSQPFFVAEAFTGLAGKYVKLEETIKGFKEIIAGKHDNLPENAFYLVGTIEEAVEKAKTL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y3626_CITBB
Sequence: MKVAYFDCFAGIAGDMTVAALIELGLPLEVLRQELAGLPFSGYTLESRKVERHGVAGTSFKVTLTEADQPHRHYSGIAKMIEASGLKPRVKELAQRIFRRLAEAEAAVHGVPLERVHFHEVGAVDSIVDIVGTAIGLDYLGVEALYASGLPYGRGFVQTAHGRLPVPAPATAELMEGIPLTADIGEGERVTPTGAAIIAALADGFGPPPPMTPLGTGYGAGEKDFPELPNLLRVLLGESTEAKGHQEVLVIETHIDDMNPEIFGFLMERLLEAGALDVAFSPLQMKKNRPATCLTVIADPADLEKLSAIVLSESTAIGLRYYPARRVTAARSLETRETTLGEVAVKVLETGRVTPEYDSCRRIALEKGIPLIEVYRTVERECGQA
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: YU005_HUMAN
Sequence: MNLFCISLEGSMDSLYEPIPEQQANQENMSSRTDSPIPPFGESEQTPNNLFVGVSNLENAKPKKRKLFRRFMSENKIFEGKTVNDKIWQEHSKHKNDSHIRRPCQLKDLNENDFLSNNIHTYQGKTLQGTSYQVTSECWSPFHYQRHVETTVDELVRHFFPDVTI
What are the official names of this protein?
Putative uncharacterized protein ENSP00000383407.
Protein: MURE_NITEU
Sequence: MMSTSSDSRSDEGHAACLLNQLDVKVRHLVADSRKLKPGDTFLACAGERHDARNDIPQAIARGVNAIIWEKQGFSWKPEWKIPNLGVAGLRHEAGKIASEAYGHPSRHLWLVGITGTNGKTTCSQWYAQAMAALGKKTAVIGTLGHGFPGALYPSEHTTPDAVYLQQLMAEYLHQGASSLVMEASSHGLSQDRLIGSEFAVAVLTNLTRDHLDYHDSMDAYAAAKAKLFFWEGLQYAVLNLDEVLGVELSQQLAGKDLSIIGYGFKQPRQTAQTAGNQKILYGSNLQFTTQQIGFDVEFCNRYASLQCNVTGRYNAYNLLAVLAALLASNIDLDDAITALRQVQPIPGRMEKLGGGNQPVVIVDYAHTPDALNEVLTGLRETLAGTRIKKRIRKNQAKLICVIGCGGDRDRGKRPLIGEIASRLADEVIITSDNPRNENPADIISEVMLGASGKHCTSEVDRTAAIYRAIHGARKGDIVLIAGKGAETSQEIQGKKYPYDDREVVRQVLHDLAGPELQVQG
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3679_BACP2
Sequence: MAGKQLSTKTVVAIGIGAAVFVILGRFVSIPTGIPNTQIETSYAFLALMAVLFGPVAGALIGFIGHLIKDATTFGPWWSWIIVSGVVGLLIGFISNRLKVEEGDFGWKKITLFNAVQAGAQALGWFVIAPVLDIVIYAEPANKVFVQGIVAGISNIITVGVLGTIIIAAYAKTRSKSGSLSKETS
What are the official names of this protein?
UPF0397 protein BPUM_3679.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYD_STRA3
Sequence: MKRSMYAGRVRSEHIGTSITLKGWVGRRRDLGGLIFIDLRDREGIMQLVINPEEVAASVMATAESLRSEFVIEVSGVVTAREQANDNLPTGEVELKVQELSVLNTSKTTPFEIKDGIEANDDTRMRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDNLEFIDVETPMLTKSTPEGARDYLVPSRVNQGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLSDQEIQDIVEGMIAKVMKDTKGLEVSLPFPRMAYDDAMNNYGSDKPDTRFDMLLQDLTEIVKEVDFKVFSEASVVKAIVVKDKADKYSRKNIDKLTEIAKQYGAKGLAWLKYVDNTISGPVAKFLTAIEGRLTEALQLENNDLILFVADSLEVANETLGALRTRIAKELELIDYSKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPTAETAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDTQERMFKALGFSAESAQEQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLVSEQQLEELSLTVESYEN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCCA_ORYSJ
Sequence: MASRLLLLPRRRSRHGGASLLLARLLSSSSSEAGGGGAVEKVLVANRGEIACRVMRTARRLGIPTVAVYSDADRGALHVRAADEAVRLGPPPARESYLNASAIVDAALRTGAKAIHPGYGFLSESADFAQLCKAEGLTFIGPPPSAIRDMGDKSASKRIMGAAGVPLVPGYHGAEQDIELLKLEANKIGYPVLIKPTHGGGGKGMRIVQRPEDFVDSVLSAQREAAASFGINTLLVEKYITQPRHIEVQIFGDQHGNVIHLYERDCSLQRRHQKIIEEAPAPNVTAQFRSHIGEAAVSAAKAVGYYSAGTVEFIVDTLSGEFYFMEMNTRLQVEHPVTEMIVGQDLVEWQIRIANGECLPLSQEQVPLNGHAFEARIYAENVPRGFLPATGTLHHYRPVPSTATVRVETGVEEGDTVSMHYDPMIAKLVVWGESRNAALVKLKNSLSNFQIAGLPTNVGFLQELAGHSAFEKGLVDTHFIERYQNDLLSTSTQALSGSHEAEELGAILAAACICKKDHVSSEVSLHDKKLSMWYAHPPFRMHHFAKRLMEFELDRELGGSSDDLLKLSVTYRSDGTYFVETEDGSSPGLDVKVDSRGDHDFRVDVGGLQTDVTLAFYSKDNCNHIHIWHGKHHHHYRQTLRAEQSPDDSSQPSASSEARSHPKGSVLAPMAGLVVKVLLKDGARVEEGQPVMVMEAMKMEHVVKAPCAGYVEGLKATAGQQVFDSSVLFTVKENKPN
What is the function of this protein?
Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.
What are the official names of this protein?
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial, MCCase subunit alpha, 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DSBG_PSEAE
Sequence: MRLPRNLITLGLGLTLLNAGLATAAEELPAPIRMVQEKGARILGSFDAPDGLRGYAAEYQNQGMALYLTPDGKHVLTGHLFDAQGKDLSREPLERLVYAPLAKEMWQKMEQSAWIADGRADAPRVVYLFSDPNCPYCTMFWEQARPWVDAGKVQLRHIMVGIIREDSEAKSAALLASKDPQKALHDHEQAGKASTLKPLAKIPAAVRKQLAGNMELMESMGAAATPAIFYLNAEGRMQQQQGAPQPDQLAEILGPR
What is the function of this protein?
Involved in disulfide bond formation.  Functions probably as a disulfide isomerase with a narrower substrate specificity than DsbC.  DsbG is maintained in a reduced state by DsbD (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbG.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbC subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: VPS10_PENRW
Sequence: MIPRWLLLTLSLLLVWASHPAAAKGNEPNIVTHELDAPPADLFYFHGTNTILYRDRRSLTAHVSFDGGEEWETVKGNDGTIEGTVDLIWRHPFDDNRAYILGENGKHWITTDQAKSWRPFQVDVLPFASMRSFPLEFNGWDPKKVIFMGLDCTILGCLPQTFYTTDDFETVKPLREMTLQCMWAASRPQFALDIDMPKSTGDRILCVVPGLKGPFEHTRTERLIYSDSFFKDDAEGTEAKLDHGKPLSGVSLQIRSVSKYIVARLQSRGTQEQALYVSDDSNVWHRAEFGKHRIEEDAYTILESTNYSIQIDVQTTWQDNRMGSLFSSNSNGTYFTQNIEHTNEDLNGLVDFERVTGIHGITIVNTVKNWEEAKKSDSNKKKLISSISFDDGRTFQPLKADKDELHLHSMTTYAALHEMPLPDHRMFSSPAPGLVMGVGNTGGHLEDYSKGDLYVSDNAGLTWRRALKGPHRYEFGDQGGVITAVLDSSQTDKVQFSIDHGKEWESISLGQKIRPLFLVSTPDSTSLKFLLVGTSSDDTTKTLMFFIDFDGLHERECGSGDLEEWTARLNEKGEPDCLMGQKQFFQRRKANADCFIKKEFAISGPEFQLCKCSAEDFECDYNFVRSEDRKECVPAVPLTPPAGKCKDPSDKYMGPSGWRLIPGNACIREGGEDLEREIERSCSNVTGPPLITDGKPRAGKPQTISAKWTNYFYLERQASNNGVDETIMMLTDKYELHVSRDHGRNWKQIHPDEKFIEMVQHPYFSDTAFFLTDGKRVYYTINHGDSFHFFDAPSVPNKEYIRKLAFHEKFQDSLIWIGHKDCEGKNCRSQAYVTDKRGASWEPMLIGIADGGCNFGYQEGRNNSEKLVICEQYKDEEKNNNRQLVISDDYFSTMEVKFENIARSATKNGFEVVAWYEGDQKEYLNASVSVDGRTYANAHFPFNIKVPQYTVLPSSPHALFLLVMVNGGGERSFGSLVKSNSNGTYFVQSLEGLNVNDRGYTDYDELQGLEGVAIANVVSNREEVLNKGAAKKLRTMITHNDGGQWMLLAPPSKDVDGKNFDCSVTEGKGTEKCALHFHGYTERRDYRDTLYSGSAIGLMLALGNVGEHLTSASEADTYLTRDGGISWTQVKKGQYMWEFGAAGSVIVLVSDRKATKVVHYTLDEGMSWHEFQFAEKELVIDDISTVPSDTSKKFLLWGIDGGKRVIVTLDFSGIWSRDCNDDESDYYNWAPTHPFQEENCIFGHVEEYHRKKPAAECWNAWREPHIHSIGRNCTCTRADFECDYNYEIQTDGSCGLVPGLQPQDHVAQCSQDPDKVEYWEPTGYRRIPQTTCEGGLLLDQDVSKPCPNKEEEYQKKHGISGTGLFFAIVTPIAVAVAVGWYAYTHWDGKFGQIRLGDSGGSQSWLSRDSMLVAVPVALIAGIVAVAQSLPLLVKSLARSSSGLFGRRGMQRPYATRGSFAARRGDYSSVVDDEDELLGADDFDDEEDQA
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin vps10, Vacuolar carboxypeptidase sorting receptor vps10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: MUTL_SHEON
Sequence: MGIQILPPQLANQIAAGEVVERPASVVKELVENSLDAGASRIDIEIDKGGSKLIKIRDNGSGIPKEELALALSRHATSKLHSLDDLEAILSFGFRGEALASISSVSRLTLTSRTAEQSEAWQAYAEGVEMAVKVMPAAHPVGSTIEVVDLFFNTPARRRFLKSDKTEFTHIDEWLKRIALVRGDIHFTLTHNGKTVRNYRPAMNEPQYLQRLTQVAGRPFADEALRVECQHDDLRLSGYLQSPWSTVLTDTHYFYVNGRLVRDRLVNHAVRQAFAQKAEVEQPGYVLMLDIDPHQVDVNVHPAKHEVRFHQSRYVHDYILQALQSALEEAGELRFEPHSPQIDDSSPYVKPETESSAFELQSTESNAKYLGIDTTGERQAEARVVEYRSSDMPKMRTGTAVQSNAFGSMSVPRETRSGSSGESRPRAELPSKTAIASYGALLQTPSYSVQDKAYQPTLPMPSILDGQFWVFTDGPKLSLLRIESVALATRSDEIETKLATGLIGQPLLMPVSVAADTDWSSLLDEHATLIRQLGLELTIRYQQLIIKKVPPYLRDCQLARVIPEWLQSLRFEAPAPNALAIWLAEQSLTGFISAPDVWVAYCQLTEEKRQQIASKAVSLPWQSWLEEQAIE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: VB10_VACCA
Sequence: MDSGIYETPINYKKSNVSAVSVNNTIFVTGGLFINNSNSTIVVNNMEKLDIYKDKQWSIIEMPMARVYHGIDSTFGMLYFAGGLSVTEQYGNLEKNNEISCYNPRTNKWFDISYTIYKISISSLCKLNNVFYVFSKDIGYVEKYDGLPAIKALSTSPY
What are the official names of this protein?
Kelch repeat protein B10.
What is the protein family that this protein belongs to?
Belongs to the poxviruses Kelch family.
Protein: CLCN5_PONAB
Sequence: MAMWQGAMDNRGFQRGSFSSFQNSSSDEDLMDIPATAMDFSMRDDVPPLDREVGEDKSYNGGGIGSSNRIMDFLEEPIPGVGTYDDFNTIDWVREKSRDRDRHREITNKSKESTWALIHSVSDAFSGWLLMLLIGLLSGSLAGLIDISAHWMTDLKEGICTGGFWFNHEHCCWNSEHVTFEERDKCPEWNSWSQLIISTDEGAFAYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVACCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIRTNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENRFNTSKGGELPDRPAGVGVYSAMWQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLEAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMANQDPDSILFN
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges chloride ions against protons.  Important for normal acidification of the endosome lumen.  May play an important role in renal tubular function (By similarity).  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons.  The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable).
What are the official names of this protein?
H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: SECF_RICFE
Sequence: MQIYPLRLLPNKIDFDFMNFKKVSYSFSIILSLISFIWIGIYKFNFGIDFAGGIVIEVRLDQAPDLPKMRGVLGELGIGEVVLQNFGSERDLSIRFGSSSEENLMKNIELIKASLQSNFPYKFEYRKVDFVGPQVGRQLIEAGAMAMLFSFLAIMVYIWVRFEWYFGLGILIALVHDVILALGFMSMTKLDFNLSTIAAVLTIIGYSVNDSVVIYDRIRENLRKYHKKNITEIINLSINETLSRTILTVITTLLANLALILFGGEAIRSFSVLVFFGIIAGTYSSIFISAPILTMFANRKFNKKVIER
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THB_CAIMO
Sequence: MSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYEGKCVIDKVTRNQCQECRFKKCIFVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKTIGHKPEPTDEEWELIKIVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLVCVERIEKCQEGFLLAFEHYINYRKHHVAHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
What is the function of this protein?
Nuclear hormone receptor that can act as a repressor or activator of transcription.  High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
What are the official names of this protein?
Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCA_SALCH
Sequence: MKIYLVGGAVRDALLGLPVKDKDWVVVGATPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEADLQRRDLTINALARDDDGQIIDPYHGRRDLEARLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLALMREMTAAGELEHLTPERVWKETENALTTRNPQVYFQVLRDCGALRVLFPEIDALFGVPAPAKWHPEIDTGVHTLMTLSMAAMLSPQLDVRFATLCHDLGKGLTPKNLWPRHHGHGPAGVKLVEQLCQRLRVPNDLRDLAKLVAEYHDLIHTFPILQPKTIVKLFDAIDAWRKPQRVEQIALTSEADVRGRTGFEASDYPQGRWLREAWQVAQAVPTKEVVEAGFKGIEIREELTKRRIAAVANWKEKRCPPPAS
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RS11_CLOPS
Sequence: MAAQKVKKTRRRKERKNVEHGAAHIQSTFNNSIVTLTDAKGNALAWASAGGLGFKGSRKSTPFAAQMAAETAAKAAMEHGLKSVEVYVKGPGAGREAAIRSLQAAGLEVTLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DMP2_ARATH
Sequence: MSKTFKAIRDRTYSGVGDLIKLLPTGTVFLFQFLNPVLTNNGHCLLINKYLTGVLIVICAFSCCFTCFTDSYRTRDGYVHYGVATVKGLWPDSSSVDLSSKRLRVGDFVHAFFSLIVFSVISLLDANTVNCFYPGFGSAGKIFLMVLPPVIGVISGAVFTVFPSRRHGIGNPSDHSEDDASEMK
What is the function of this protein?
Involved in membrane remodeling.
What are the official names of this protein?
Protein DMP2, AtDMP2.
What is the protein family that this protein belongs to?
Belongs to the plant DMP1 protein family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Vacuole membrane; Multi- pass membrane protein.
Protein: PO3F3_XENLA
Sequence: QADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPAAQEITTLADSLQ
What are the official names of this protein?
POU domain, class 3, transcription factor 3, Homeotic protein NRL-20, XlNRL-20.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSPLO_ARATH
Sequence: MEHESKNKVDGMEMEKGKKESGSRKGLELTMRVLALVLTMVAATVLGVAKQTKVVPIKLIPTLPPLNVSTTAKASYLSAFVYNISANAIACGYTAISIVIVMISKGKRSKSLLMAVLIGDLMMVALLFSSTGAAGAIGLMGRHGNKHVMWKKVCGVFGKFCNQAAVSVAITLIASVVFMLLVVLDALKLP
What are the official names of this protein?
CASP-like protein 1E1, AtCASPL1E1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.