PharMolix/UniProtQA huggingface dataset:
Protein: ARL1_YEAST
Sequence: MGNIFSSMFDKLWGSNKELRILILGLDGAGKTTILYRLQIGEVVTTKPTIGFNVETLSYKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKDRMSTASKELHLMLQEEELQDAALLVFANKQDQPGALSASEVSKELNLVELKDRSWSIVASSAIKGEGITEGLDWLIDVIKEEQL
What is the function of this protein?
Recruits golgins such as IMH1 to the Golgi.  Can bind and hydrolyze GTP.  May be involved in trafficking events within the endosomal system.
What are the official names of this protein?
ADP-ribosylation factor-like protein 1, Arf-like GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: CC85B_DANRE
Sequence: MGSDSEILNRELSKLSDEDLLACTKEELVNRLRKEESDKMSALIQRGRLIKEVNKQLQGHLLEIRELKVINQRLQEENQELRDLCCFLDDDRLKVKKLAREWQLFGHHAAKVMREDLGGYLKKLADLERMQDGLVKENLDLKELCLVLEEECVSRSDSSPGGSTDLNIPCMVARDVGDGSSSTGSVGSPDQLHLVCSPDD
What is the function of this protein?
Functions as a transcriptional repressor.  May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth (By similarity).  May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (By similarity).  Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (Probable).
What are the official names of this protein?
Coiled-coil domain-containing protein 85B.
What is the protein family that this protein belongs to?
Belongs to the CCDC85 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, adherens junction.
Protein: RUTA_ACIAD
Sequence: MKIGVFCPIGNNGWLLSENAPQYMPSFELNKKIVQRAEHYGFDFALSMIKLRGFGGKTEFWDHNLETFTLMAGLAAVTSKIKIYATAATLVMPPAIVARMASTIDSISNGRFGLNVVTGWQAPEYSQMGMWPGDEYFAKRYEYLSEYVQILRELWATGQSDFKGEHFQMEDCRVSPQPQAEMKIICAGQSDTGLEFSAQHADYNFVFGKGLNTPTAYAGINDRLKHFTDQTGRDVQTYVLFMVIAAETDAEAMAKWQSYNDGADVEAINWLMNQGGKDTKSGADTNIRQMASSVSPVNINMGTLVGSYEKVAAMLDEIAEIKGTEGILLTFDDFVQGVEDFGERIQPLMTSRQDIVAEYQPVTPLEKSA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: RPSH_BACLI
Sequence: MNLQNNQGKFSKEQFSKERFCQLEDEQVIEMVHVGDSDALDYLITKYRNFVRAKARSYFLIGADREDIVQEGMIGLYKSIRDFREDKLTSFKAFAELCITRQIITAIKTATRQKHIPLNSYVSLDKPIYDEESDRTLLDVISGAKVMNPEELIINQEEFDDIELKMGELLSDLERKVLALYLDGRSYQEISEELNRHVKSIDNALQRVKRKLEKYLELREISL
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation.
What are the official names of this protein?
RNA polymerase sigma-H factor, Sigma-30.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
Protein: TMCAL_NATTJ
Sequence: MQGLGIIAEYNPFHNGHLYHITNSLEQIRPDFVMAVMSGNWVQRGEPAIIDKWTRAEMALNQGVDLVVELPFLWATQSAREFAQGAVALLKDSGVISYQSFGSETGDLTLLQRAAKLSLEESEHFRQTLHNYLDQGFNFSEALAKALNLNELASNDILGIEYLKSHDLLSSDISCITVQRQGSPYHKSEISGKFSSATAIRQAAKNGDLSLIKHTVPDQTWNLLSQNKTDWIFFKMLEQHILYKFRITNKETIEQLMEWEQGLENRIYNASLDSCTLEEFISKLKTKRYTRTRLNRLMLHALMEIDKSLLNHFNTTGPPYLRVLGMNQRGRQALKTISDRASLPILTRPARDLRSLSHYCRQCFHWEVKASAFYNLLKQKDGREEYIRPPIVHPD
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMP3_NEIGO
Sequence: MTKQLKLSALFVALLASGTAVAGEASVQGYTVSGQSNEIVRNNYGECWKNAYFDKASQGRVECGDAVAVPEPEPAPVAVVEQAPQYVDETISLSAKTLFGFDKDSLRAEAQDNLKVLAQRLSRTNVQSVRVEGHTDFMGSEKYNQALSERRAYVVANNLVSNGVPASRISAVGLGESQAQMTQVCQAEVAKLGAKASKAKKREALIACIEPDRRVDVKIRSIVTRQVVPARNHHQH
What are the official names of this protein?
Outer membrane protein P.III, Gonococcal protein III, PIII.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: ALD1_STAEQ
Sequence: MRNFTKQYINGEWVDSASGETIDVINPATEEVMGKIAKGNEEDVNKAVDAADKVYLEFRHSSVEERRELLDKIVKEYQNRKNDLIEAITDELGAPLSVSENVHYQMGLNHFTAARDALDSFQFEEQRGDDLVVKEAIGVAGLVTPWNFPTNQTSLKLAAAFAAGSPVVLKPSEETPFAAIILAEIFDKVGVPKGVFNLVNGDGSGVGNPLSEHPKVRMMSFTGSGPTGSKIMEKAAKDFKKVSLELGGKSPYIVLDDVDVEEAANATTKKVVNNTGQVCTAGTRVLIPESIKEDYLTAVKEAFSKVKVGQPREEGTQVGPIISKKQFDQVQDYIDKGINEGAELFYGGPGKPEGLDKGYFARPTIFINVDNHMTIAQEEIFGPVMSVITYNNLDEAIEIANDTKYGLAGYVIGKDKDTLRHVARSIEAGTIEINEAGRKPDLPFGGYKESGLGREWGDYGIEEFLEVKSIAGYFK
What are the official names of this protein?
Putative aldehyde dehydrogenase SERP1729.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: Y0787_DICDI
Sequence: MISNKRKEIDTIDGHHEKDNDDDDSDGIDNGLLTYKKFKKDFDSGSTNYRELQIIAKSLGLASNGKKQLVYNRIEGYFLSKKVKNNLTNNETNQQEEKKEEEQQQPQPQEKQYILTFKDVEPVENYFWKVFRNIVIFKHIFSNFKNKQYGYYDLIGCDRSYLNDTSNSMEIIIDNIKSNNNHQIIRNKINIANIIHKFKKNDEKTKSFYNLLFSRYSSTSTSSTIQFDENIDKWIQAMIGHVNFTALDQFIKFFKIDSEVIKKVMKIHIDPSVFGNTTYDKLKIYNYLKSINSLPTSHTLLPFISTDLSKFLSFDNKFKKLIKSYKRLIESTNLQERMEQQKQKEKIKIHPSNIKYYEKLNQIILELNEIQTSQFTNDQLNSTIKNLLNHTTPTSTSTSTPNLTITSTASNNINLKEIIKKYYKSICLFFYCTVNSATEMFFRKPLLYYLNFKKESVDKMYERVVNKWNGRSFDHQLFFQSILKDINIEKNEKFELISNVLDNKYVKTFKEYDHYIFFKAVFSSNDIELIDYFLKILMQQPNKIQKITRYPNIGKLIGNYCNLIDKKEILDFYFQNYRDESLLFDDQNEIWKQIQLELIEHYEYLMDSIGKRCKLDFTPWFDQNFLDRLNRAILKPSVYSIGFDGYFDIVFEGLVDLNIKDNKENSIINFLSNAQLKHPLDLKFFESSFNPYKGKMLTFIKFLFNNISKESIETKLKVINLKTDNKNFEEIKSKIELTTTLTATTTTTTANLLSPKKSKDVGCLTIGKTESFNFTISIRMLLVCLYNLDRVDDIIYLFDKLPEVLFNPDYFSIFTNEYCIYGISSSYYLELFINYFIENLNNNTINYLYNCLCIASKKGYTQIFKNIISSDQNSKYLLKIQTKSNQSSLFDSKLLNDIVVKSINSSNFELSNLLIDFIDFSAKDKNSLKMKILKSK
What are the official names of this protein?
UPF0746 protein DDB_G0280787.
What is the protein family that this protein belongs to?
Belongs to the UPF0746 family.
Protein: NUON_GRABC
Sequence: MNWTLASPEIVLALCGLVILLVGVARNRREDTFLCAMLTLGAFLVTGLLTVSGALGLGFQGQFVADPFAVMVKLLILSGASIAVVLSLDYNRHHGMERFEFPVLTLFSTVGMMVMVSASNFMTLYMGLELMSLAIYVLAAFARDELRSAEAGLKYFVLGSLASGLLLYGISLIYGFAGTMDFSALREALAHPAGTSPGLTVGVVFVIAGLAFKISAAPFHMWTPDVYEGSPTPVTAFMGTAPKVAAIAMMLRTLVTPFHGVLVQWQHVVALISVVSMVWGALAAIGQTSIKRLMAYSSIGHMGYALVGLAAGSQAGIRGLLIYLVTYVFMNTGTFACILAMRRRGRQLEKVSDLAGAGRTDPALALLLAIFMFSMAGIPPMSGFFGKLYVFLAAVQAGEPLLWGLAVIGVLTSVIGAYYYLRVVKVMYFDDASEGPFEAWPTSVSVVAVGSAIFTALFFLFPAPILAAADLAAKALLR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TTL4_ARATH
Sequence: MSHYRRHSLEPSITSKFRDSLSFQRDDDVINKPDFRELDFGSPLRPRGSSSAAATPAASGSSSSSSGSASGKPAVTSQFARRSHSGELSGLSQTSPVKPGSVNRNLKPGHRRSASAGTPLIYSGLGFSPVNNNNNSSRGGGSGATSPNPGVLPTGNICPSGRILKTGMATRASVRPETLCTGTANYGHGNIIRTGGKVSHATKAAAEMSDSEEVKKAGNVMYRKGNYAEALALYDRAISLSPENPAYRSNRAAALAASGRLEEAVKECLEAVRCDPSYARAHQRLASLYLRLGEAENARRHLCVSGQCPDQADLQRLQTLEKHLRLCTEARKIGDWRTVISEIDAAIANGADSSPQLVACKAEAFLRLHQIKDSDLCISSIPRLDHHHTQPPEKLFGIVCDAYVLCVQAQVDMALGRFENAIVKVERAMTIDHSNSPEVVSVLNNVKNVAKARTRGNELFSSGRYSEASVAYGDGLKLDAFNSVLYCNRAACWFKLGMWEKSVDDCNQALRIQPSYTKALLRRAASYGKLGRWEDAVRDYEVLRKELPGDSEVAESLQRARNALSNKSEEPKYLGFNNEVEEVSTLDKFKTATSLPGISVFHFKSSSNRQSEAISPFVNTLCLRYPLVHFFKVDVEESLALAKAESIKKIPTFKIYKKGEKVKEMVCPSHQLLEDSVTHFLL
What is the function of this protein?
Involved in osmotic and salt stress tolerance.  May play a role in the control of meristematic cell size during osmotic stress.
What are the official names of this protein?
TPR repeat-containing thioredoxin TTL4, Tetratricopeptide repeat thioredoxin-like 4.
Protein: ORML1_XENLA
Sequence: MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGMLHIVLLSIPFFSVPVAWTLTNVIHNLGMYVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFLTISPIILYFLASFYTKYDPTHFFINTASLLSVLIPKLPQLHGVRIFGINKY
What is the function of this protein?
Negative regulator of sphingolipid synthesis.
What are the official names of this protein?
ORM1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the ORM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: OBG_SYNJB
Sequence: MHFIDQAEIEVQGGNGGDGIVAFRREKYVPAGGPSGGNGGRGGSVILVADPGLQTLLDFRFQPVIKAEHGAKGGPNHRSGASGADRLVRVPCGTVVFNAETGELLGDLVGKGDQLLVARGGKGGLGNAHFLSNHNRAPRQFTKGEAGERVRLRLELKLIAEVGIVGLPNAGKSTLISVVSSARPKIADYPFTTLQPNLGVVPHPSGDGVVFADIPGLIEGAHLGVGLGHEFLRHVERTRVLIHLVDGTAADPVKDYQVIQQELRAYGHGLIDKPQILVLNKIDVLDPQQVAERAQRLSAAAGTSVVTISAIAKQGLDPLLQRVWQCLGRGSQQPAQLDLVGAKSIQS
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_SHIDS
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLPRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LYL1_MOUSE
Sequence: MCPPQARAEVGSAMTEKTEMVCASSPAPAPPSKPASPGPLSTEEVDHRNTCTPWLPPGVPVINLGHTRPIGAAMPTTELSAFRPSLLQLTALGRAPPTLAVHYHPHPFLNSVYIGPAGPFSIFPNSRLKRRPSHSELDLADGHQPQKVARRVFTNSRERWRQQHVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQTAVLTSGPSAPGSRKPPARRGVEGSARFGAGHRVEAARSQPVLPGDCDGDPNGSVRPIKLEQTSLSPEVR
What are the official names of this protein?
Protein lyl-1, Lymphoblastic leukemia-derived sequence 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROP_ECO57
Sequence: MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVTVFGEMEFWFAIIKVIAVVAMIIFGGWLLFSGNGGPQASVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPVNTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGVVTRFPALLYPLGNWICLLFMAVVLVIMLMTPGMAISVYLIPVWLVVLGIGYLFKEKTAKAVKAH
What is the function of this protein?
Permease that is involved in the active transport across the cytoplasmic membrane of all three aromatic amino acids, phenylalanine, tyrosine and tryptophan.
What are the official names of this protein?
Aromatic amino acid transport protein AroP, Aromatic amino acid:H(+) symporter AroP, General aromatic amino acid permease.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNH2_STAA1
Sequence: MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPITKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAEB_ASPCL
Sequence: MARLSLLTLLALGSAALAKKDTFQTKCAALQHKVKLPNVHVNFVEYVPGGTNLDLPDNAPSCGASSQAVSTDMCRIAMAVDTSDSSQITLEAWFPRDYTGRFLSTGNGGLSGCIQYYDLAYAAGLGFATVGANNGHNGTSGEPFYQHPEVVEDFAHRSVHTGVVVGKQLTKLFYDKGFKKSYYLGCSTGGRQGFKSVQKYPKDFDGIVAGAPAFNFVNLISWSAYFYSLTGSNTSESYLSPAMWKIAHDEIVRQCDELDGAKDGIIEDTDLCHPRLETIICKPGAKDTANCLTGAQAKTVRDVLSPMYGVNGTLLYPRMQPGSEVYAAGIMYNGEPFQYSTDWYRYVVYNNPDWDDTKWSVEDAAAALAQNPYDIQTFDADISSFRGAGGKVLTYHGLQDQMISSDNSKLYYARVAETMKLPPSELDEFYRFFPVSGMTHCAGGDGAYGIGNGLGSYNGVDPENNVLMAMVQWVEKGIAPEFIRGAKFAEGPGSAVEYTRKHCRYPRRNVYKGPGNYTDENAWECV
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
What are the official names of this protein?
Probable feruloyl esterase B, Ferulic acid esterase B, FAEB.
What is the protein family that this protein belongs to?
Belongs to the tannase family.
What are the subcellular locations of this protein?
Secreted.
Protein: DSG21_DANRE
Sequence: MARRISPVVAFLLCFGLSHFFEAEARLQHSVALHRQKREWIVPPQILEENVDYTKKDFIAKIRSDKEVAHMKYLRYSLRGVGADQEPFNLFVVNPETGYVRITGILDRESISQYNLSGIALFTDGSIAENDIGLRIKVKDQNDNAPVFGVMNPGAVDELSAVGTEVMRLNCFDADEPGNPNSQIKYEIVDQQPAGQSMFTVENNRRVVVANPNLDRETVDQYVLLVKASDLNGAPGGNAATGTVTIKINDVNDNVPTLGGPYEASIEENTEKVEVMRLKVSDLHLKGTDNWEGDCYIASGNEAGYFSIHMDPKTNEAVLMLDKAVDYEDVKDLNLGIGVANKAPFHPSVSGGSQGATISFGGSGGGAGSGAAGGAGAMGGASGSGGGTGASSWSSSGVPLYNVNIKVKNQPEGPKFFPGTKAIPISEGKAFDSTEIIARYPAIDTDTGKEATNVKYIKSSDPDNWLTIDEKTGAIRMNKAPDRESKYLVNGTYYAKVLSITQDLPSKTATGTIAIQVEDFNDHCPTLISNVQTLCTDKDAVLVTAKDEDAPPNGAPFDFNIVSEGTAGKWTVEYMNDTTAIFRTHEKLWPGPHELMVEVTDQQGLKCPEPQKLQVDVCTCKNQGGCDRTATGDAKKGSRLGPAGIGLLLLALLALLLIPLLLLLCTCGMTGAFTDMPFETKVHLISSNTEGQGEDRDVPLMCPPSNVDGMGFMTKDYMAVGAMHSAGLGLGVGAGVGAAGFLESTSTMGGRGYNEMELDYMNSIGRNNAYSSRDMAGDFDGMALSDGYLCEYYSQKSRVVDGFGKDDPMVYDYEGKGSPVGSVGCCSLLEDQNDLEFLNDLGPKFTTLADICGGKKTEIPAPAPAPLPPPPKPVVDRSEVVSSTTNILNTGNIATNRVNTVNVASNMATASSTRVENVLVTDNRPTMITSVHPAPTLLVQPQPMYYMVEQQPSTVLVAERPAMTQGMYVLNSGPVAEGMVVQGGNIAANTLTRGERMVLVFRGGPAQALNNGMLHTSNLSGSQLLLVDGGATSGQVLQGTIQRGVAGSQGLMFVDGQGGQVIQGSINNGISTHGGSQNVFYVENKGGSSVVQGGLQMGKASTAGSLIGDVGIGGSSVKITQNPSSHKVVVQERKVVTTQSVK
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion (By similarity).  Required for embryogenesis, specifically for progression of epiboly and normal convergence-extension movements during gastrulation (PubMed:22235774).
What are the official names of this protein?
Desmoglein-2.1.
Protein: RIB1_PICGU
Sequence: MASKDIVHPQPERRHGSETHEFTMPLLSPTLTPSHIPSQTPQIPPEVPAEVRDRLPLPETLPVVKCMARARIPTTQGPEIFLHLYENNVDNKEHLAIVFGEDVRSKTLYQKRPNETQQDRMTRGAYVGRLFPGRTEADYDSESNLRLNFDENGQLIRDPSTTCSGEPILARIHSECYTGETAWSARCDCGEQFDEAGRLMGEAGHGCIVYLRQEGRGIGLGEKLKAYNLQDLGADTVQANLMLRHPADARSFSLATAILLDLGLNEIKLLTNNPDKIAAVEGRNREVKVVERVPMVPLAWRSENGIKSKEIEGYLSAKIERMGHLLEKPLKI
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: MATK_BACCT
Sequence: MEEFQGYLELDRYRQHDFLYPLLFREYIYALAHDHGLNKSILSENAGYGNKSSSIIVKRLITRMYQQNPLIFSANDSIQNPFFGHNKNLYSQIISEGFAVIVEIPFSLRLVSFLERKEIAKSKNLXSIHSIFPFLEDKFSHLDYVSDVLIPYHIHLEILVQTLRYWVKDASSLHLLRFFLHEYWNTLITPKKYITLFSKGNPRLFLFLYNSHICEYESIFLFLRNKSSHLRSTSSGIFFERIYFYVKIEHFVKVFFDNDFQCILWFFKDPFMHYVRYQGKSILASKDTPLLMNKWKYYLVNLWQYHFYAWFQPGRININQLCKYSLDFLGYRSSVRLNSSVVRSQMLENLFLINNAMKKFETIVPIIPLIGSLSKANFCNTLGHPISKPTRSDSSDSDIINRFLRICRNLSHYHSGSSKKKSLYRVKYILRLSCVKTLARKHKITIRTFFKKSGSEFLEEFLTEEEVVLSLIFPRTYSSSRRLYREQSWYLDITSINDLVNYE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1897_STAS1
Sequence: MADESKFEQVKGNVKETAGNVMDNKDLEQEGKEDKASGKAKEVTENAKDKVNDFIDKLKK
What are the official names of this protein?
UPF0337 protein SSP1897.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: PNP_MARMM
Sequence: MFDIQKETIEWAGRPLTIETGRVARQADGAVMVSYGETTVLATAVGVKQAKPGVDFFPLTVNYQEKYFAAGKIPGGFFKREGRPTDKETLTSRLIDRPIRPLFVKGFKNEVQVMLTVLSHDLENDPDIVGMIGASAALVLSGLPFMGPIGAARVGYKDGEYVINPPCDEMDDSELDLVVAGTQDAVMMVESEAKELSEEVMLGAVMAGHKAFQPVIDMIIKLAERAAKEPWDYAPADHSAEEAKVRDLIGDDLAAAYTIVDKTERYKAVGAAKDKAVEALLQTEERPDGIDMTTLKDVMKAVESSIVRGGIIKTGKRIDGRSLDQVRSIVSEAGILPRTHGSALFTRGETQALVVATLGTGEDEQFIDALTGTYKERFMLHYNFPPYSVGETSFRLAPGRREIGHGKLAWRAVKAVLPTKEDFPYTIRLVSEITESNGSSSMATVCGASLSMMDAGVPITRPVSGIAMGLIKDPEGIAVLSDILGDEDHLGDMDFKVAGTTEGVTSLQMDIKIAGIDEEIMKTALAQASGGRLHILEEMGKALGEARTELGEFAPRIETITIPTDKIRDVIGSGGKVIREIVETTGAKVDVNDDGVIKVSSSDGASIKAALDWIHGLTAEPEEGQIYKGKVVKVMDFGAFVNFFGPKDGLVHVSQLKAERVNHPSDVVKEGQEVYVKLLGFDDRGKVRLSMKIIDQETGEEIKKEQEDAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGLY1_MACFA
Sequence: MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVESSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSPDPPSASTVTPDSAILGVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRVRKLDKGTNISDEDFLLLELLHWFKEEFFHWVNNILCSKCGGQTRSRDRSLLPNDDELKWGAKKVEDHYCDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSKDEVVDVTWRYSCKHEEVIARRTKVKEALLRETINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETSFIPSENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKIDSISIRTTSQTFQTGTIEWKLRSDTARVELTGDNNLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL
What is the function of this protein?
Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation.  Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp.  Prefers proteins containing high-mannose over those bearing complex type oligosaccharides.  Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins.  Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins (By similarity).
What are the official names of this protein?
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, PNGase, N-glycanase 1, Peptide:N-glycanase.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase-like superfamily. PNGase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_STRPI
Sequence: MEHSSWHALIKAQLPEGYFGKINQFMNQVYVQGTVYPPKEKVFQALLTTPLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDLGVKKSHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWGAYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_META3
Sequence: MINSKTKLLGLIGHPVEHSLSPTMHNEAIKDKDLNYVYLAFDVESENLKDVVNGAKAIGWKGFNITIPHKIEIMKYLDKIDNDAKLIGAVNTVKIENNKAIGYNTDGIGARLSIEEIIGEVKDYNILVIGAGGSSRAVCCELAKNNNLTIINRTVEKAEIIANDLSNKLNNAVYYGGLNHNYNMANFDIIINTTSLGMYPNVDNKPPISMQNIKKDAVVMDLIYNPKETLFLKEAKEKGCATINGLGMLIYQGAKSFEIWTGVKPDINIMKNAIIDIL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CBPYA_ASPFN
Sequence: MRVLPATLLVGAASAAVPPLQQVLGRPEEGMSFSKPLHAFQEQLKTLSEDARKLWDEVANYFPDSMDHSPIFSLPKKHTRRPDSHWDHIVRGSDVQKIWVNNADGEKEREIDGKLEAYDLRVKKADPSALGIDPNVKQYTGYLDDNGNDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFMELGPSSIDENIKPVYNDFSWNSNASVIFLDQPVNVGYSYSGSAVSDTVAAGKDVYALLSLFFKQFPEYAEQDFHIAGESYAGHYIPVFASEILAHKNRNINLKSVLIGNGLTDGLTQYGYYRPMGCGEGGYKAVLDEATCESMDNALPRCRSMIESCYNSESAWVCVPASIYCNNALIGPYQRTGQNVYDVRSKCEDESNLCYKGMGYVSEYLNKAEVREAVGAEVGGYDSCNFDINRNFLFHGDWMKPYHRLVPGLLEQIPVLIYAGDADYICNWLGNKAWTEALEWPGQKEYASAELEDLKIEQNEHTGKKIGQVKSHGNFTFMRLYGGGHMVPMDQPEASLEFFNRWLGGEWF
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: DHA1_STAAW
Sequence: MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSGFSNDMYEKEGAKIVTHEQAWEADLVIKVKEPHESEYQYFKKNQIIWGFLHLASSKEIVEKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGVHENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLQDMYAEKDVTVVKSTPENLAEQIKKADVFISTILIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTIETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNIDYILEICDKGLEQAIKDNEALSTGVNIYQGQVTNQGLASSHDLDYKEILNVIE
What is the function of this protein?
May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer.
What are the official names of this protein?
Alanine dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.