PharMolix/UniProtQA huggingface dataset:
Protein: LEXA_MAGSA
Sequence: MLTRKQYELLMFIDERLRATGISPSFDEMKDALDLKSKSGIHRLITGLEERGFIRRLAHRARALEVVRLPENRNDQTLPPPAKAFAPNVIKGGFAASQLAGAPVAGPSDSVTLPLYGKIAAGTPIEALRDHSNSVDIPASMLGSGNHYALTVDGDSMIEAGINDGDTVVIRSCDSAETGTIVVALVDDTEVTLKRLRRKGTSVALEPANKAYETRVLPPDRVKVQGRLVGLLRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: DML1_COCIM
Sequence: MREIITLQLGQRSNYLATHFWNVQESYFTYSENEASPVDHDISFRPGIGADGSETFTPRTIIYDLKGGFGSLRQYNALYEVEENVGMPKGLWDGNEVIQRQPNIPQSEYQKALELGLPLPRLTPETVRYWSDFNRLFYHPKSIVQLNEYEMNSQLMPFEDWTVGEAFFNSLDREHDLLDRDFRPFAEECDQLRGIQLFTGTDDAWGGFAARYIDRLRDEFGKKIIWTFALESGLKTEREKQFLRAKNSAKSISEISRQSTAYVPISMPPSKLPHYVNLNIASEWYISALTSVAVESVTLPGRLRWYEGIEPWFLDNAGPQRIFALRATIRSENSELPFASHLRPNDSTQMDTDEVDHDEIEQSEQRFDLGFSPIGSATRTNNTHIFSQVQVVRDSKCNSERPERAEVGQGLTSHRLSLMTGYVPSTLSNFRSTLEFPILDSFPSDLIHEQGPAGSTLRVDAALSATSGIGRDLKNLQQTIGRRIALEEREDLINGLHELSHAYQAGWENDSDSGDD
What is the function of this protein?
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
What are the official names of this protein?
Protein DML1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RNP3_AERPE
Sequence: MGLIDISVKPQTEQCSEVLRTAGRLGYTAVAIPPESADECMSLEGDGIPRLYRRGYVEASTRRDVRRAAEKLAGVVDFIVVKPLTLEAARYAAANKRVHIIRVDGSNLWAADRGTAEIMAQRGWGALEVSLRNLTLNPGSPAAWRALAVVLRRSFAYGVHVFLASDAEEPHELWSPYSGASLAALLGVPWSHAMLYNSEERLRILLDASRA
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 3, RNase P component 3, Rpp30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU120_SCHPO
Sequence: MNELKHAVVPIDLQSFCLEGTLALWVPALENDSEDDSEAIETADDNEKLFKKECVAYDAGVYTSNKSKGSQTLRWSIFQNRTLTIFDVSLNSKKEPLSKFNVKIHFPSNVMKDGVAFSFSEHSDTTIIYAITHARVLYYIRLSKTWFQLPDARLDDDWCLCYRPISFLNQKPDLMAAISTSEICVSFFNGGLTKIILNPKDASHYEQHIDDSSYLFSLKKYLSLQAFKADYRSPNTIISMIFLSTYNVLVMLSLDYKLKVLDLSTNQCVETIELSQTILPLQSFPYLTSDHTTNSFIALYYPDNSHGSFSIYKLNANAHSFKLNVVIEKGIIPPSLPDDEFIPWMLSDFQLISSEGSQSKFLLIIAWKSNLNTVIQKCNLSLDQDESFSCVWSHSLDSFSLIEKTFFDVPTNMSSGDISEIWLQHIFAHNTSIESIQVALLSFQNSSSQVSKNKLDKFGALTISELKNAVLSSIVSTIQIEPNSDLTGYDYYEYKRLLYNEWERFAKLVAYLDHFGDEILSINFDPSNAVTYINYANKVAFIRDPYLIESFDEEPLTKLISSLETDDPSLIEGYQILDLGRSLHSCMSFSTLSEIRYSLRELVQDLPSYSLFDTLWVFYDKHIYPNVDPDYISTLIDTLVSLENPMRDIDSLIQRLRSFDIYNHSAQSPSLFLCASVARVLDSILKKFQVSIEGFIFLLSLITSQQDYELQSKFAGCDKLFLSLLEDWRLVSFLLENSALLLEKFEEEDVDSTNCNLNTMEALASVNTALQFFSALNYSECFSESQISPLHATVISSLSAIFIRDDTENDLVTELVEKLFLFKQYNACMQLIGWLNSDPIAVYLKALIYLKSKEAVKAVRCFKTTSLVLYSHTSQFAVLREFQEIAEKYHHQNLLSCYYLHLSKKLFEESAYIDALEFSLLADASKETDDEDLSIAITHETLKTACAAGKFDAAHVALMVLSTTPLKKSCLLDFVNQLTKQGKINQLLNYSMPTLRQDVDNLLERKAFQMINVESQPCWYNILFSWRYKHQNYRDAAAIIYEKLSRYISTTELIGKKERTFIIEHYLIVLNTLELLPKEDTWILVTDMSVDKEPDPNFLPQKLLTLDAIVAEYHLQLKDVAVQVTAEMSSAMNIDL
What is the function of this protein?
Functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.
What are the official names of this protein?
Nucleoporin nup120, Nuclear pore protein nup120.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear rim.
Protein: PUR5_FUSNN
Sequence: MINSYKDSGVDKEEGYKAVELMKKNVLKTHNKSVLTNLGSFGAMYELGQYKNPVLISGTDGVGTKLEIAMKQKKYDTVGIDCVAMCVNDVLCHGAKPLFFLDYLACGKLDAEVAAQLVSGVTEGCLQSYAALVGGETAEMPGFYKEGDYDIAGFCVGIVEKEDLIDGSKVKEGNKIIAVASSGFHSNGYSLVRKVFTDYNEKIFLKEYGENVTMGDVLLTPTKIYVKPILKVLEKFNVNGMAHITGGGLFENLPRCMGKNLSPVVFKDKVRVPEIFKLIAERSKIKEEELFGTFNMGVGFTLVVEEKDVETIIELLTSLGETAYEIGHIEKGDHSLCLK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_SHEB8
Sequence: MTAEPNKPCQIKRDYPQLINLYPATADTDAHYLSKLSIYQQRVFEAHSQQKLLVLGQIGLSNGLELLSWWRAHSHLSQRLLLKVFEPNPINAYELKLLWDQSACLTKEPELEPLAQRLLHAEPAAIIGCQRLIFDDGRFTIDLHFGDIQSQLSSLIHSPMHPVQHWLILPHLLQALHHQSHWQMAKLSDDSATIATIGLSESSGLSETTVNRFQACGFTVSDINELGIHQPVTLINHQPDAVLLHERQVLRQQDAKAYAFNPMAAILSSATQSSIAIIGGGLASAHLALSLAERGQGAQVFCKDAELGQGASGNRQGAIYPLLTPENDELSRFFQQAFLFSRRRVQALTSAPADNQTPISHVFCGVLQTAHDERSQLRLDKIIQGQPWPSEIAYAVDAEQANAIAKINLDKPGFFYPLGGWVCPFEYADAAIQKAMQLADVSVSLNTDILAIERQSDGWVLLTEKERLGPFAQLVLANGAELTQFDASNKLQISPFRGQVSHVPAQFQLSQLATVLCANGYLTPSHQGLHCLGASYVKEPKHLDFCPQEQQENLAKMHESYPKQSWLEDIDMSGNNARVGVRMVTRDHFPMMGCAPDVPKIIKDYAQHQLTKESRHYWQTTPAPVHQGLYILGGLGSRGLSSGPLAAECLAAQLCGEPIPLDKATLCKLNPNRMWLRKLLKGKAL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_HELHP
Sequence: MQEIMAKLEQLENLNDLERLRVEVMGKKGILTQQFALLKNLEGETKKTFAKELNKNKENFEKMLESKRESLLKVQMNENLTKEVVDASLFTALRPKSNGHPIYQTMDRIIDFFVNMNFAIQTGPLVEDDFHNFEALNLPVFHPARDMQDTFYFKDSMLLRTHTSPVQIRTMQSQHIPIRMIAPGSVFRRDYDLTHSPMFHQVEGLVVDEKDKISFVHLKYILEDFLHYMFGDVRIRFRSSFFPFTEPSAEVDISCVFCGGSGCRVCSHTGWLEVLGCGIVNQKVFDAVGHKNVSGYAFGLGVERFAMLLHRVNDLRSFFETDLRVLEQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA1_BORA1
Sequence: MVSLLKKLIGSRNDRLLKQYRKLVTQINNLEPQIAALSDEALQAKTQEFRDRHAKGTSLDDLLPEAFAVVREAGKRVFGMRHFDAQLLGGIALHNGKIAEMRTGEGKTLMATLPVYLNAIAAKGVHVVTVNDYLARRDADWMGRLYRFLGMSTGVVVPQQPNEEKIAAYRADITYGTNNEFGFDYLRDNMEYRVEDRRQRGLAYAIVDEVDSILIDEARTPLIISGQAEDHTELYVRMNAVPPLLKRMAGEPKPHEPEPEGDYWVDEKSQQVHLSESGHESAEKILTRLGILPEGESLYDPRHIALMHHMMVALRAHTLFFLDQQYVIQDGEVVIVDEFTGRLMAGRRWSDGLHQAVEAKEGVKIQHENQTLASITFQNYFRMYEKLSGMTGTADTEAYEFQEIYSLETVIIPTNKPMQRKDQNDQVFRTSQEKYNAILNDIRDCHERGQPVLVGTTSIENSELLSGLLKKAKLPHEVLNAKQHAREAEIVAEAGKPGHITIATNMAGRGTDIVLGGSVEKQIDLIRADENLSEAEKTARIERVRQEWKPLNEQVKAAGGLRIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLMRIFAGDRVRAIMERLKLPEGEPIEAGMVTRSIETAQRKVEGRNFDIRKQLLEYDDVANDQRKVLYAQRNDVLEAKTIGASVENLRDAAVTELFRGFVPAESVEEQWDIAGLQQALASDWQLQLPLAEMVEAEPKLTDEELLERVLQAARDTYRSKSELVGEESWGQFERSIMLQSIDTHWREHLSALDYLRQGIHLRGYAQKNPKQEYKREAFELFSGMLDRIRDDVVRVLMTVRVQSTEQVAQAEAEAAQSHVQNVQFHHSDYDEALASEAAEAQEPVRNVLPKVGRNDACPCGSGKKYKQCHGKLT
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RL30_BDEBA
Sequence: MAKMAKTFVVTLKRSTIKCTQDQKDAVRVLGLKKIRQTVEVKDSAAARGNIMKVQHLIDVEVKG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: UPPP_BIFAA
Sequence: MNFFQAIFLGLVQALTEYLPVSSSAHIRIIGDLMLGSDPGAAFTAIIQIGTELAVILYFRHDIIRILGAWFGSLFGKEGKDFKSRMGAHNRDTQMGWFIIIGTLPILIAGLLFKDAIESTLRNLWITVTVLIIFGILLWVVDARAKQVKTMDEMTWKDALIFGIGQMLALIPGVSRSGGTITFGRAMGYTREAAVRVSFLMAIPAVFGAGILEAVSAVKDVAAGNAGMFPGWGATIAATIVAFVVGYVVIIGFLKFVSTFSYKAFAIYRIALAVVVALLLICGVLHPTEVVAAA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL28_TROW8
Sequence: MSSVCQVTGASPGFGYAVSHSHRRTKRRFDPNVRRRTFYVATLGRRVTLNVSVKGLRLIDKRGIDAVVRDLIKKGVKL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: OR6C2_HUMAN
Sequence: MKNHTVIRTFILLGLTGDPHLQVLLFIFLFLTYMLSVTGNLTIITLTLVDHHLKTPMYFFLRNFSFLEVSFTTVCIPRFLYNISMGDNTITYNACASQIFFVILFGATEFFLLAAMSYDRYVAICKPLHYVVIMNNRVCTLLVLCCWVAGLMIIVPPLSLGLQLEFCDSNAIDHFSCDAGPLLKISCSDTWVIEQMVILMAVFALIITLVCVILSYLYIVRTILKFPSVQQRKKAFSTCSSHMIVVSIAYGSCIFIYIKPSAKDEVAINKGVSVLTTSVAPLLNPFIYTLRNKQVKQAFSDSIKRIAFLSKK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 6C2, HSA3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYA_SYNC1
Sequence: MTGNEIRSRFLKFFQDHGHTVVPSSALIPHNDPTLLFINAGMNQFKDVFLGREKRDYVRATSAQKCVRAGGKHNDLENVGQTARHHTFFEMLGNFSFGDYFKKEAIDHAWKFLTEEMGLPKDKLWVTVFREDDEAYDIWRDQQGIPEERLIRMGEKDNFWSMGDTGPCGPCSEILIDQGESMSCGDECGIGKCDCDRYLELWNLVFMQFNRDADGTMTPLPKPSIDTGMGLERITAVMQGVQSNYDCDLLRGIIAHVEELSGKRYGDNAEHDMSMRVIADHSRATAFLIADGVLPSNEGRGYVLRRIMRRAARHAKMLGFADPVLYRTATFVLQSMAEAYPEPAQRADYVAKIVKIEEERFIQTLDNGLRILTEEVERLKAANATVLPGDVAFKLYDTFGFPLDLTADILRGENVTIDEDGFEACMEEQRQKAREHWKGSGEEAISGIYRQLAEEGARTDFTGYGELTGQSEILAILLDGQPVSSAPAGAKVEIVTAATPFYGESGGQTGDCGTLAAGDAEVTITDTKKPLPELFVHVGEIAAGTLQTGETATLTVDRERRQATALNHTATHLLQAALVEVLGEHVKQAGSLVTPERLRFDFIHFSAMSAEELERVETLVNCRIRENAGVDTREMDHEQAVAEGATALFGEKYGDKVRVVRVGDISMELCGGTHANASGDIGLFKILQETGIAAGVRRIEAVTGAKALQVVRDQERTLDDLASLIKTDRPQLEARLRKLLERQKELEREIESLQGKLNADQAGDLLQQATEIDGISVVCGRVDNLDGKALRELADQVRDRLSSGVLILGSAHEGKAGLLVAVTKDLTKRLQAGALVKQLAAMVGGGGGGRPDLAQAGGSKPEQLDEALASVPQRISEALNAA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_ANASK
Sequence: MRANSKAKPVSRAALAGEADPRLVALSVSIQDDGALYAEDIRGSQAHVSMLAAQGIVPKAAARRIVAALDQVRAEFAAGKIRFDPALEDVHTHVERRLGELVGKDAGYLHAGRSRNDQVALDERLFIVGACDRCDAALERLQRAFLGQARAHERTILPGYTHLQRAQPVSLAHHLLAYVEMFGRDRERFAEVRRRAAISPLGSGALAGTTLPLDREAVAARLGLAGVTHNSLDAVSDRDSAAELLFACALAAVHLSRIGEELVLWTTKEFGFATLSDAFATGSSLMPQKKNPDVGELARGRAGRALGDLVALLAILKGLPLSYNRDLQEDKRPLLGGPEALVLTADAVAGAVETATFHAARMEEALGSGEALATDAAEYLVDRGVPFREAHEAVGKAAAFSAREGRPMARLTAAEWATFHRRFEKDVLRCFDARRSLRRRELPGAPGPRAVRAELRRWEKALGKARG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPD1_KLULA
Sequence: MGISLWLCPYGHSPEYETFKTLIESLQTLFPNSPVFEPHVTVCSGLSCENMEEVHKVLEMAHHAINAVKSKVDSENALVEFDGFNIGKKYFEKCRLECKPNPMLYSLAKLIRSMFVGELNIDTWLFEEFHPHLSLAYSDIYPMDQAMIRLIRQRIEDLFDVTTEEIESHSRDQDAYKLQHTLKGWSFPLTFKVVRCEGPVEEWEVLSEVTVHG
What is the function of this protein?
Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.
What are the official names of this protein?
2',3'-cyclic-nucleotide 3'-phosphodiesterase, CPDase.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. CPD1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: GPPA_ECOL6
Sequence: MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLTVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFYDQVENEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIDQESQWQSYVHWPLEVH
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: GLB3_PETMA
Sequence: MPIVDSGSVAPLSAAEKTKIRSAWAPVYSNYETTGVDILVKFFTSTPAAQEFFPKFKGLTTADQLKKSADVRWHAERIINAVNDAVVSMDDTEKMSMKLGDLSGKHAKSFQVDPQYFKVLAAVIADTVAAGDAGFEKLMSMICILLRSAY
What are the official names of this protein?
Globin-3, Globin III.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: Y1404_STRPN
Sequence: MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDSYKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK
What are the official names of this protein?
UPF0223 protein SP_1404.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: PUR7_SHESM
Sequence: MSLADSVLAVNNDLPIRTDNPVHSGKVRSVYWLTDADSRRLIQTKGYNVPEDTPLAIMVISDRISAFDCIFHGEGGLKGIPGKGAALNAISNHWFKLFAENGLADSHILDIPHPFVWIVQKARPIKVEAICRQYITGSMWRAYSKGERVFCGITLPEGLEKDQKLPDLLITPSTKGILTGIPGVPAQDDVNISRSDIEANYQAFGFEKVEDIDLYEKLLKDGFKVIAKALADLDQVFVDTKFEFGYVTDKNGNSKLIYMDEVGTPDSSRIWDGAAYRDGKILENSKEGFRQFLLNHFPDPDILLNKDRMPEREALARDNALPLEAMMDVSRTYTGIAEKVTGAAIPLPANPKADIIKILREEYDLIV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: DPO4_SULTO
Sequence: MIILFVDFDYFFAQVEEVLNPQYKGKPLIVCVYSGRNEKSGAVATANYEARKLGVKAGMPISRAMELAPNAIFVPMHKEVYTEVSNRIMSIISSYSDKIEIASIDEAYIDITSKVKNFEEAIELGKKLKREIMEKEKITVTVGIAPNKVFAKIIADRVKPNGLGVVKPEEIEEFIKSIDIDEVPGVGNVISERLHSLGVNKLIDILSVSFDKLKEEIGEAKAFYLYRLATNSYFEPVLNKERVPHGRYLTLPKNTRDIKVIELYLKKAIDEAYNKIEGIPKRMTVVTIMQDLDIVSKSKTFKTGISKERAYTESIELLKQILQKDSRLVRRVGVRFDNIYKSKGLDVFFNS
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
Protein: WWAS2_HUMAN
Sequence: MTSAETASRAAESGGTPVRPCSRPHRAPSPAAPSRPGAPAAGPRKLLVPGLPCLVRGGWPWTRPDSSPFRPAARPRMSPHRSPAVARRCGRPRRRDPRRRRTPALPRPWPGRGGPGRSLLHRHLFIQQLLRTCWPALPRDRTPAPGGTMPGAALAGPGRQASGSPAPQSEGAPPRPWTPLQPGLHHRPPSSSSGLLSSFF
What are the official names of this protein?
Putative uncharacterized protein WWC2-AS2, WWC2 antisense RNA 2, WWC2 antisense gene protein 2.
Protein: TILS_ACTP7
Sequence: MLLDTLQTQFRHYFPTQRNFVLGLSGGIDSIVLLHLLAELQLNLRAVHIHHGLSPNADNWAAFCEQVCKRLKIPFILQKVTVDRSEGIEAGARAARYQAIGEIIQPNEVLVTAHHLDDQTETFLLALKRGSGIKGLSAMQAVGFWQNFTIFRPLLNVSKAQIEQYALQQQFTWIEDESNHDSHYDRNFLRNEVLPIVNQRWQHFSQMVARSAQHCAEQQMLLEELLAQELQRYADFSEKRLNIEAFPQFSLAKQQQLIRLWLEKCGAQMPSTAQLMQIIQQTIYADVDKNPQLKLADFWLRRYQHHLYLTGELLEPDDFCQPLFAQQSLTLPDGIGELQHLGDSIIYQKSGKIDRLLLPKVLVNAPLQVKLTHQGKVKQYAKPMREEMKKRYQQAQVPVWLRKRTPLIFFHDQLVFICH
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_RHIEC
Sequence: MQSITIRRPDDWHLHLRDGAILEGVIADTSRTFARAIIMPNLVPPVVTTADAKAYRERILKALPDGHRFQPLMTLYLTEQTSPDDVEAGAASGLITAVKLYPAGATTNSHGGVRDMEKAMPVLERMAKIGLPLCVHGEVTTPDVDIFDREAVFIDTVLDPLRRRLPELKVTMEHVTTAGGIDYIKAAQGNLAGSITTHHLIINRNAILVGGIRPHYYCLPVAKRENHRLALRAAAVSGDPRFFLGTDSAPHVDPLKECACGCAGIYTSINTMSCLAHVFEEEGALDRLEAFASLNGPAWYGLSPNEERITLSKQADPVVFPAKIETGAGAVTVFDPMVPLHWQVSASA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: LEXA_COLP3
Sequence: MIDSTTELRPLTKRQQQIYDLIKAKIQDTGMPPTRAEIANFFGFKSANAAEEHLKALAKKGYIEMLAGTSRGIRLVEEMLEAEGLPLIGRVAAGEPILAQEHIEEHYKMDGNLFHPAADYLLRVNGESMKDIGILDGDLLAVHQTTEVQNGQVVVARVENDVTVKRFKREGNVVYLHAENEDFSPIKVDLANQEFNIEGIAVGIIRSGRWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: NEMO_DROME
Sequence: MSDEESFVILGSSPCSSLMPDSSLRSDVCGNAQEAEETVASTSTQPPTVNCIPVSITASQQQHKSLDSGSSQQQSLATSFIMGEIQSDVLKNSVYSQFPSLCSLQGSAEEVVKLQNMMTEYLALKSTLDKVNQTMLNYHNLTQQWRQEAADREHQYKEHVKECQAQIAILRVENQELKRDLETKIEQIEGVHTIRLKEQDELRKSVSEKQSLIDNMRVEIDKLKQLNHSFEFVPEYATESKSQELIKKMQLDINELKARDIQKQEVIKGLQIQNDIYRRDFEMERADREKNAGEKDQYLMDLRSLQRRNQELIEALAESHKASKACSTASPLSSSRSNLREEQRPILDPTGASSRTSDTTLRCPICSKSFNALSVLQSHVNDCLDKN
What is the function of this protein?
Essential signaling component in transmitting the lipopolysaccharide (LPS) signal leading to cact degradation, which is required for NF-kappa-B (Rel) activation.  Required for antibacterial immune response.
What are the official names of this protein?
NF-kappa-B essential modulator, Inhibitor of nuclear factor kappa B kinase subunit gamma, DmIKKgamma, NEMO homolog.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UGPE_ECO57
Sequence: MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQAVYAAPMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWPLLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGLVDSEK
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
sn-glycerol-3-phosphate transport system permease protein UgpE.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSLAB_HUMAN
Sequence: MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARCKHVHAALRFQGALRRNRCAIM
What is the function of this protein?
May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the regulation of arterial pressure.
What are the official names of this protein?
Ras-like protein family member 10B, Ras-like protein VTS58635, Ras-related protein 17, RRP17.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: LPPX_MYCTU
Sequence: MNDGKRAVTSAVLVVLGACLALWLSGCSSPKPDAEEQGVPVSPTASDPALLAEIRQSLDATKGLTSVHVAVRTTGKVDSLLGITSADVDVRANPLAAKGVCTYNDEQGVPFRVQGDNISVKLFDDWSNLGSISELSTSRVLDPAAGVTQLLSGVTNLQAQGTEVIDGISTTKITGTIPASSVKMLDPGAKSARPATVWIAQDGSHHLVRASIDLGSGSIQLTQSKWNEPVNVD
What is the function of this protein?
Might be involved in translocating phthiocerol dimycocerosates (PDIM) from the cell membrane to the outer membrane; PDIM forms part of the cell wall.
What are the official names of this protein?
Putative phthiocerol dimycocerosate transporter LppX, Lipoprotein LppX.
What is the protein family that this protein belongs to?
Belongs to the LppX/LprAFG lipoprotein family.
What are the subcellular locations of this protein?
Cell surface. Secreted, cell wall. Secreted. Cell membrane; Lipid-anchor.
Protein: SPRY3_MOUSE
Sequence: MDATVIDELQQILPIEQLRSTHASNDYVERPPAPCKQALSSPSLIVQTHKSDWSLATMPTALPRSISQCHQLQPLPQHLSQSSISSSMSQSTTASDQRLLASITPSPSGQSIIRTQPGAGAHPKVDGALKGEAEQSVGHSSDHLFICEECGRCKCVPCTAVRPLPSCWMCNQRCLCSAESLLDYGTCLCCVKGLFYHCSTDDEDNCADEPCSCGPSSCFIRWAAMSLISLFLPCLCCYLPTRGCLHMCQQGYDSLRRPGCRCKRHTNTVCRKISSSSSPFPKAQEKSV
What is the function of this protein?
Inhibits neurite branching, arbor length and neurite complexity (PubMed:26089202).  Inhibits EGF-mediated p42/44 ERK signaling (PubMed:16877379).  Negatively regulates the MAPK cascade, resulting in a reduction of extracellular matrix protein accumulation (By similarity).  May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis (By similarity).
What are the official names of this protein?
Protein sprouty homolog 3, Spry-3, Sprouty RTK signaling antagonist 3, Sprouty3.
What is the protein family that this protein belongs to?
Belongs to the sprouty family.
What are the subcellular locations of this protein?
Cytoplasm.