PharMolix/UniProtQA huggingface dataset:
Protein: ACSA_LEPBA
Sequence: MPKERIVAPSKEFAKLANVSLKEYKSKYKESIEKPEKFWAEQAKRLTWFKKWTKVLRHDFAKAKVEWFVGGKLNVSYNCLDRHLDSPLKNKAALIWEGDNPDESKVLTYHDLHREVNHFANVLKKFKVKKGDRVLIYLPMVPELAIATLACTRIGAVHSVVFGGFSPEALLGRIEDCKPTLVITADGGYRGGKPIELKKNVDAALAETKFKVNDVIVVKRTGDEGNLNWKEGRDHWYHYLMKDPEVKKECPAVPMESEDPLFILYTSGSTGKPKGVLHTTAGYLLGANLTFATIFDYKDTDTYWCTADIGWITGHSYILYGPLSNGATSLMFEGVPSYPDMGRFWDVIDKYKVTVFYTAPTAIRALMREGLEHIKKRSLASLRLLGSVGEPINPEAWEWYYANIGKSKCPIVDTWWQTETGSIMISGIPGAIPQKPGSASWPFYGIQPVLVDNEGVELKGKGEISGNLCIAKPWPSMMRGVYGDPKRFFDTYFSQFKGYYFTGDGANRDKEGYFRITGRVDDVLNVSGHRIGSAEVESALVEHKSVAEAAVVGFPHDIKGQGIYAYVTVKQGVVTNDLLKKELIAMVEKVIGKIARPDVIHWAPGLPKTRSGKIMRRILRKIANNEFDTLGDISTLADPSVVQSLIDDKKKYHS
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL27_SYMTH
Sequence: MFLQLFASKKGVGSTKNGRDSNPKYLGVKKGDGSLVTVGQIIVRQRGTKIHPGANVGRGKDDTLYALADGIVKFGRKGANRKQVSVVPIQLAVEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: FOLD_PYRCJ
Sequence: MSGKPLHEKTKEWARRHVRLLEEVGVTPKLAVLLLNDDPVELETQRRYVSLKARDVREVGGEVEIYELVDVPPERRSKEALYLIERLNRRDDVTGILIQKPVPPFVDEDLLFQRLSPEKDVDALTPENKKRLLALFDLDRDLLPCTPAGILELLQMYGVEVKGRDVTVVGKGELVGKPLAVMLMQLDASVSVLHALTRDKLRYVKEADIVISAVGRPPELYRDNPWRLTGDMVKEGAVVVGVGGKVDPATGKWYFDVDEKSVAEKASYLTPNLGGVGLATRARLLKNLIRASYNVARATAAPRLLKAF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: 5MP2_MOUSE
Sequence: MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQSVEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD
What is the function of this protein?
Translation initiation regulator which represses repeat-associated non-AUG (RAN) initiated translation probably by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function (By similarity).  Enhances histone H4 gene transcription but does not seem to bind DNA directly (By similarity).
What are the official names of this protein?
eIF5-mimic protein 2, Basic leucine zipper and W2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the BZW family.
Protein: SSPA_HISSO
Sequence: MTSAANKRSIMTLFLDKVDIYCHQVRIVLAEKGVAYATEIVDSESISEDLMELNPYGTIPTLVDRDLVLFNSRIIMEYLDERFPHPPLMPVYPVSRGKSRLLMLRIEQDWYPVLEKAEKGSESERAIALKQLKEEILAIAPVFSQSLYFMSEEFRLVDCYIAPLLWRMQQLGVVFTGTGSKAIKSYMERVFQRDSFLQSVGEMTPKNLMEDK
What is the function of this protein?
Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme.
What are the official names of this protein?
Stringent starvation protein A homolog.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. HSP26 family.
Protein: UPPP_STRR6
Sequence: MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNEAFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGVFKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYIGLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKAGELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSFVRLFV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DTD_AZOVD
Sequence: MKALIQRVAKAQVTVAGEEVGAIGPGLLALVGIEPQDDRESIGRMLHRLLNYRVFADAEGRMNLSLAQLGGGLLLVSQFTLAADTRSGLRPSFSSAAPPAQGQALFEALLALARERHPQVAGGRFGAHMRVELVNDGPVTFLLEA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIA_SALG2
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQVLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_STRMU
Sequence: MANEFINFEKISRKTWQHLHQESQPPLNENELNSIKSLNDRISIKDVTDIYLPLISLIQIYKKSQENLSFSKSIFLQKNISNRPFIIGVSGSVAVGKSTTSRLLQLLLARTFKDSSVELMTTDGFLYPNAVLSSRHMLNKKGFPESYDMERLLDFLDTIKNGQSAEIPVYSHEIYDIVPNKSQIIEVPDFLIIEGINVFQNPQNNRLYMSDFFDFSIYIDADSDYIENWYLERFATLLDLAKNDKQNYYNRFLKLGEKGALDFARDIWKDINLVNLEKYIEPTRSRAELILHKTKNHKIDEIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLR_STAEQ
Sequence: MTNILIVEDEQNLARFIELELTHENYTVDIENDGKAGLDKALSKPYDLYILDLMLPNINGLEICRQIRQKTTTPIIIITAKSETYDKVAGLDYGADDYIVKPFDIEELLARIRAVLRRQPDKDVLDINGIIIDKDAFKVTVNGHQLELTKTEYDLLYVLAENRNHVMQREQILDHVWGYNSEVETNVVDVYIRYLRNKLKPFNKEKSIETVRGVGYVIR
What is the function of this protein?
Member of the two-component regulatory system ArlS/ArlR.
What are the official names of this protein?
Response regulator ArlR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_DESVH
Sequence: MLCIGIETSCDETGLALVRDGRLVHAVMSSQADIHALFGGVVPEIASREHYRLIGPLYDLLLREAGVGPTELDAVAVARGPGLLGSLLVGMAFAKGLALGFDIPLVGVNHLHAHLLAAGLERELVFPALGLLVSGGHTHIYRIESPVSFRLLGRTLDDAAGEAYDKVAKMLRLPYPGGRILDQQGRRGIADPRLFPRPYTDNDNLDFSFSGLKTAVQTHLSRHPELVPSPDAAQAVAGGHDAPEGLRNMCASFNEAVAETLCIKLGRALDGDDGVGVRALIVAGGVAANSYVREHTARLAVSRGLELIVPSPPLCTDNGSMIAYAGWLLRQGGLSHSLDLEAVPRGRAIPDDYRQGPAGCS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOO_BACSU
Sequence: MIRLSILDQSLIGEGETAADTLQHTVKLAQMAEECGYHRFWVAEHHNNDEIAGSAPEVLLGYLAASTRKIRLASGGVMLQHYSSYKVAEQFHLLSALAPGRIDLGVGKAPGGFQLSTDALQAEYKKPVRQFDEKLEELTHFVRDDFPDTHRYAALRPRPQVDRKPGIFLLGGSTESAISAAKLGISFVFAYFINGEEEVLKEARRAFDAHLPPGSEAEFHLAPAVFAAHTKEEAEKHIVSRESIKVVLKDGRKVNVGSREQAEAYLENVTEPYDIIVQKTGIIAGTKEEVAEELTRLSGTYKINDFVIFTPIKNAVEKQLSYQLLSDAVLAAKR
What is the function of this protein?
Involved in a cysteine salvage pathway from S-alkylcysteine.  Catalyzes the oxidation of N-acetyl-S-benzyl-L-cysteine and N-acetyl-S-methyl-L-cysteine to (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide and (R)-N-acetyl-S-methyl-L-cysteine sulfoxide, respectively.  This pathway is likely important in the catabolism of alkylated cysteine generated by proteolysis of alkylated glutathione formed in the detoxification of a wide range of electrophiles.
What are the official names of this protein?
N-acetyl-S-alkylcysteine monooxygenase.
What is the protein family that this protein belongs to?
To bacterial alkanal monooxygenase alpha and beta chains.
Protein: HIS2_BRUA4
Sequence: MTEFTLSDLERIVAERAGMTDGSSYTASLVAKGQTRAAKKLGEEAVETVIAAVEGNRADVVTESADLLYHLLVVLKIADVPLNEVLAELQRRTAQTGLEEKAGRPKA
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_ALTMD
Sequence: MAKRCLIMAGGTGGHVFPGLAVANALRAEGWDIHWLGTAERMEAQVVPKHDIPIHFIPVKGLRGKGISARIQGAVALVKSLFSARRIIKRLQPDIVVGFGGYASGPGGVAAKSLGIPVIVHEQNAAAGMTNKLLSKLASRVLLGFDDAKEQFSGAADNVHTVGNPVRDDIWQVKPKKRESYAGATSLNMLVVGGSLGAQILNETVPETCGVLNGLSIKHQCGKGNSDGVVKAYESVGADMANVELSDFIDNMAAAYEWADFIVCRAGALTVSEVAASGRAAIFVPLPFAVDDHQTKNAQSLVKQNAALMIAQSVLKQNLGQAVRRWLEHPEDCLKMGALAKTCASIHATENVVSHVKSVVGEGD
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HB2F_MOUSE
Sequence: AAVVVLMVLSSPGTEGGNSERHFVSQFKGECYFTNGTQRIRSVDRYIYNREEYLRFDSDVGEYRAVTELGRSDAEYYNKQYLERTRAELDTVCRHNYEGVETPTSLRRLEQPNVVISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEMAPRRGEVYTCHVEHPSLKSPITVEWRAQSESARSKMLSGIGGCVLGVIFLGLGLFIRYRSQKGPRGPPPAGLLQ
What are the official names of this protein?
H-2 class II histocompatibility antigen, A-F beta chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: KAPL_APLCA
Sequence: MAHNQVFPESQKWLKEYLESSLEQFENLFNKNVISTESIRNYTLIRTLGSGSFGRVMLSQHGGDNPQKCYAIKILNKEKVVKMKQVEHTMNEKRILLSIGSPFVVRCLNAFKDTTNLYMVMEFVNGGELFHLLRKKGRLPEYWCTFYAAQVTMALQYLHNCSLLYRDLKPENILLDHLGYLKVTDFGFDRRVQGHTWTLCGTPQYLAPEMILNRSYASQWTTGGLGILIYELNAGFVPFDHKVPLKLYELIVECRLTFPSFFKPTLRDLLTNIIQVDVTRRFGNLRNGALDIINHPWFKDTDFRKILMKAEKAPWVPNLKGQWIHQTFDKWTEESISISKHDKYPDEFSNF
What are the official names of this protein?
Spermatozoon-associated protein kinase, SAK, C-APL-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein: FMT_SHIF8
Sequence: MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSPIKVLAEEEGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEMPRLGCINIHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVATGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GSK3B_XENLA
Sequence: MSGRPRTTSFAESCKPVQQPSSFGSMKVSRDKDGSKVTTVVATPGQGPDRQQEVTYTDTKVIGNGSFGVVYQAKLCDTGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQALPIIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRARTPPEAIALCSRLLEYTPTSRLTPLDACAHSFFDELRDPNLKLPNGREFPALFNFTTQELSSNPSLSSILIPAHARNQAAVSTTSNTTSTSDSNTGERGSTNNAASASASNSS
What is the function of this protein?
Plays a role in the organization of the formation of the main body axis of developing embryo.  Acts as an inhibitor of differentiation of primary neurons.  Inhibits the ability of ectopically expressed NEUROD1 and other bHLH factors to promote early retinal cell differentiation.  May participate in the Wnt signaling pathway.  May regulate the circadian clock via phosphorylation of the major clock components.
What are the official names of this protein?
Glycogen synthase kinase-3 beta, GSK-3 beta, Xgsk-3 protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane.
Protein: DNAK_KARMG
Sequence: MSKIIGIDLGTTNSCVSVMEGNSPVVVPNSEGKRTTPSIIAFIEGGETKVGDPAKRQAVTNPSKTIFSIKRFMGRNFSEVTEELKNIPYKIIKGENDTPRVSIGNKLYTPQEISAMILQKMKKTAEDYLGNEVKQAVITVPAYFNDAQRQATKEAGEIAGLNVERIINEPTAAALAYGLDKNNQNKKIVVYDLGGGTFDISILELGDGVFEVLSTSGDTHLGGDDFDKVIIDWLVKEFKVEQGVDLSNDSMAYQRLKESAEKAKIELSSSTKTEINLPYITATPSGPKHLVKTLTRAKFEELSDDLIKRSLYPCKNALKASNLISKDIDEVILVGGSTRIPKIQEQVEKFFEKIPSKGVNPDEVVSIGAAIQGGVLSGDVKDVLLLDVTPLSLGIETLGGVFTKLIDSNTTIPTKKSEIFSTATDNQSAVTIRVGQGERSMFNDNKEIGRFDLIDIAPAPRGIPQIEVTFDIDANGILNVSAKDKSTGKEQSIRIQASSGLSKNEIERMKKEAQENADKDNKIKEEIEKINSADSIIFQTEKQLKEYGNKISEETKKKLEINLNNLKDARNSKNISDIDNYINKINNILSSSYQEIYKNNESVKNNESVKNNESVKNNESVKDVDFEEIK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SURE_RHOBA
Sequence: MRILLTNDDGVHAPGLAALRQQLRHLGEVITVAPATEQSGVGHSITYLTPLVPKSIHRDGVHWAWAVEGSPADCVKLSLAELFVDEPIDLVVSGINNGLNAGINVLYSGTVAAAIEGAFFGVTSVAVSLENSDDNDFDAAAVIARNVIGEIVRHEESRGGLFNLNVPTAATESASEVKVVPMGLAQYGRRYEKRQDPGGRDYYWALWTQPDKPPAEMTDVTQLREGCVTLTPLHFNLTRDDLLSEMKDWNLRP
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_CICAR
Sequence: MAVGKNKRISKGKKGGKKKAADPFSKKDWYDIKAPSVFQVKNVGKTLVSRTQGTKIASEGLKHRVFEISLADLQGDEDNAFRKIRLRAEDVQGKNVLTNFYGMDFTTDKLRSLVRKWQTLIEAHVDVKTTDNYTLRMFCIGFTKRRSNQVKRTCYAQSSQIRQIRRKMREIMVNQATSCDLKELVRKFIPEMIGKEIEKATSSIYPLQNVFIRKVKILKSPKFDLGKLMEVHGDYSEDVGTKVESPADETVVEGTPEIVGA
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAR_XENLA
Sequence: MLPATFKLCAGISYRHLRNMTGLRRTAAVALTHELEKLALVGPGPGKWINQIRRKSILLSSRLEEKTLNDVEMSYIKQGEEALKKSLNILGDQDGWKTEIVMENGDKVLSKVLPDIGKVFKLEAVVEKPLDNVYGELVDNMEKMGEWNPNVKEVKILQKIGKDTVITHEKAAETPGNIVGARDFVSVRCSKRRGSTCILAGMSTRFGGMPEQKGFVRGENGPTCMVLRPLAEDISKTKLTWLLSIDLKGWLPKSIINQVLSQTQVDFAKHLRSRMTSSSNALSLC
What is the function of this protein?
Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone.  Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).
What are the official names of this protein?
Steroidogenic acute regulatory protein, StAR, START domain-containing protein 1, StARD1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CLPP_LACLS
Sequence: MGYLVPTVIEQSSRGERAYDIYSRLLKDRIIMLTGPVEDGMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKSDVLTIVMGMAASMGTIIASSGTKGKRFMLPNAEYLIHQPMGGAGQGTQQTDMAIVAEQLLKTRKRLEQILADNSNRSLEQIHKDAERDHWMDAKETLEYGFIDEIMENNSLK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_SALAR
Sequence: MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQAINDLVKEAGKPRWDWQPEAVNDALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIDQLTAEDDTLDANELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSREGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKISTDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKYAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQTQPAAAPEAPTSEQGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_BIFLO
Sequence: MTEEHRLISAESVTEGHPDKVCDQISDAILDDLLAQDSSSHVAVETSAATGVFLVFGEVTSEGYCDVQSKVRETLRNIGYTSSEVGLDADSCGVVVAITEQSAEINQGVARLTGDQETAASREERYEAQGAGDQGVMFGYATDETPTLMPLPIYLAHRLAFHLTEVRKSGEVPHLRPDGKTQVTIEYDDDDKPVRLDTVLISTQHDPEVTQDWLAVELKKHVIDPVLDEVLGSKVPHDNYRQLVNPTGSFILGGPAADAGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSAAYATRWVAKNIVAAGLAHKVEIQIAYAIGVADPVSVNVETFGTEQGVTRGQIAAAVRKVFDLRPAAIIDELDLKRPIYLKTAAYGHFGRTDVEFPWEKTDKVEELKAAIAAE
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXS_NITEC
Sequence: MFMQDSDSIGIVSARRVHFDTPLSLKSRAVLDSYELVYETYGELNPERSNAILVCHALSGNHHVAGVYADNPKNTGWWNNMIGPGKPIDTRKFFVIGINNLGGCHGSTGPISINNRTGKRYGPDFPLVTTSDWAKTYVRFADQFGIDCFAAIIGGSLGGMSAMQLALDAPERVRHVAVIAASARLTAQNIAFNDVARQAILTDPDFHGGDYYSHGTHPRRGLRLARMLGHITYLSDDSMASKFGRELRNGSLAFNYDVEFQIESYLHYQGDKFADLFDANTYLLMTKALDYFDPAQDYDGNLSAAFARAQADFLVLSFTSDWRFSPERSREIVKALLDNKLNVSYAEIPSTYGHDSFLMQDDYYHQLVRAYMDNISI
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C7A94_KALSE
Sequence: MQLFYVPLLSLFVLFVSLSFYFLFYKSKSGSTSGLPLPPGKTGWPVIGESFEFLSTGWKGYPEKFIFDRLAKYSSNVFKTSLFGQPAAAFCGAACNKFLFSNENKLVQAWWPDSVNKVFPSSTQTSSKEEAIKMRKLLPNFLKPEALQRYVGVMDQIATKHFKSGWENKKEVLVFPLAKNYTFWIACKVFVSVEEPTQVAKLLEPFNAIASGIISVPIDLPGTPFNSAIKSSKIVRDKLMGIIKQRKTDLGEGKASPTQDILSHMLLTSDENGKFMTEGDIADKILGLLIGGHDTASSACTFVVKFLAELPEIYEGVYKEQMEIAKSKKAGELLNWEDIQKMKYSWNVACEVLRLAPPLQGAFREALTDFSYNGFSIPKGWKLYWSANSTHRNSEVFPEPLKFDPSRFEGAGPPPYSFVPFGGGPRMCPGKEYARLEILVFMHHVVKRFKWEKVIPDEKIVVNPMPIPAKGLPVRLFPHKA
What is the function of this protein?
Catalyzes the oxidation of the methyl group to a carboxyl group at the C-28 position of beta-amyrin to form oleanolate.
What are the official names of this protein?
Beta-amyrin 28-monooxygenase, Cytochrome P450 716A94.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RME6_CAEEL
Sequence: MADIIERIRSQDEYREFYELATKIRNQKLLTDAELHSLNRHQQEVSDNEIKLLTEAWRSSYWNNVGRQLKNQALEPTIACRLLKEISETEALPAYKHVGHHFSTLDQLLTILYNEPQSVAELLNSIDRNDITSNDSTIQVLFHLVYSCALYPEDELKIAQVVCNLLKLQLYRSGSEMRTILRKETSISTRFYKHFVELIHPTMVYLTKALRKGVLDVIQLGSFWLDIDAKQSTARFLRDNKQNEDRLPEYRALVVSKLVDFVDTFLENISKALPMLPPNLNWIIRDIFCSLYEVVDDVSAIELSHACKDMIVSNLICPAIISPQKFGVVDNDVRVGTIVNHNLVQIAMIIQMISLREFESPPEEYKEFLSQCRNTHLISEMMDALLVEKLAPDVEITSLIANGTAESDMATKSSFVGTVADVNVLIKIIRNAPSTSDAKLSRILSVCDKLPATISSTTQKSHFDNLEASPKISTLRNIHRKVQHSFKRTGDSFNDINELGAKQGEALAFGKENFDLFYLEYSPKNYKDVAEADRLKKKAEERRQLADLEKLLEPTPAPKETPVENNLIDFSSGSAETNSEHLSDSTSVSPEPLTSTEELQIGDQGVGGEQRGKLAKLKSLSDRMKKGITQSNTLSDIREHLRRSGSFVKPPPSGIPTSSSEQNLPDVATGPRDDILAKYASISSIKEQKPALGNLIDGTASASSTPRKEPLEPYYSSENLVGCRAFQDTLRKMITVLGNISYLPRIGYRNETKQNEWDKKVLLGRFLDGVLVETEHRREYGLAAQLREVKRCIELFEHAGVEILMDHLKLNEAEQDKIVNGMREERASLMRKSNDISSLEQRVLLNRRLTEQILVDFLMRTFLETGFNNKHTVGKTQEVTAVLKFYDEFKYLRAQDERAEFLKNLLTFLRDRLMQNVDWNFATDTMMSRAMTTIERYVIFAVYDNAFYPNRDADHHRDKLLRGTIAKVSDVVTPVNDFLKIPEHLHGEAPWPSAQAELSMLDIYVTAQDKLNCVVRCCDVINNLVALSSKNAVASADDLTPVLVFVIIKANPRALLSNVQFVETFAGDRIESGRDAYYWVNFKSAVEYIKTIL
What is the function of this protein?
Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in endocytosis.  Acts by regulating the activation of rab-5 by exchanging bound GDP for free GTP at clathrin coated pits.
What are the official names of this protein?
Receptor-mediated endocytosis protein 6.
What is the protein family that this protein belongs to?
Belongs to the GAPVD1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle.