PharMolix/UniProtQA huggingface dataset:
Protein: TYSY_DECAR
Sequence: MQPYLDLMRHVLDNGNDKSDRTGTGTRSVFGWQMRFDLSQGFPVMTTKKLHLKSIIHELLWFIQGDTNIKYLQENGVKIWDEWADENGDLGPVYGKQWRRWETPDGRVIDQITQLVNSLKNNPDSRRHIVSAWNPGDVDNMALPPCHCLFQFYVANGKLSCQLYQRSADIFLGVPFNIASYALFTMMLAQVCGYQPGEFVHTFGDAHLYSNHFEQAKLQLSRDTRPLPTMWINPEVKDLFAFRFEDFRLEGYDPHPHIPAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_PSYA2
Sequence: MLAKRIIPCLDVDNGRVVKGVQFVDIKDAGDPVEVAKRYNEQGADEITFLDITATSDERDTTYHTVERMAETVFVPLTVGGGVRKIADIRNLLNAGADKVAINSAAVFTPEFVGEAAQKFGNQCIVVAIDAKRVADIEVDGIIMPRWEIFTHGGRKPTGIDAVAWARKMAELGAGELLVTSMDGDGTKKGYDLALMKQITSRVNVPVIASGGVGNLQHLAEGVLEGGVDAVLAASIFHFGEYTVQEAKAYMAAQGIQMRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCA_MYCTO
Sequence: MGVELGSNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLASRGAEVLLLSDLLTEALHHSGAARMQGIAAAVDAPRLGLPLAQELSAYLRSLDPGRLAHVLTAGMTFNELPSDTRTDVSLVLRMHHGGDFVIEPLPNLVFTRDSSIWIGPRVVIPSLALRARVREASLTDLIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAEALARSLFDDDLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLEAFTIQRTPDGVTIGDAAPFAEAAAKAMGIDKLRVIHTGMDPVVAEREQWDDGNNTLALAPGVVVAYERNVQTNARLQDAGIEVLTIAGSELGTGRGGPRCMSCPAARDPL
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_BACFR
Sequence: MKLVKPKKFLGQHFLKDLKVAQDIADTVDTFPDLPILEVGPGMGVLTQFLVKKERLVKVVEVDYESVAYLREAYPSLEDNIIEDDFLKMNLQRLFDGHPFVLTGNYPYNISSQIFFKMLDNKDLIPCCTGMIQKEVAERIAAGPGSKTYGILSVLIQAWYRVEYLFTVNEQVFNPPPKVKSAVIRMTRNETQELGCDPKLFKQIVKTTFNQRRKTLRNSIKPILGKDCPLTEDALFNKRPEQLSVQEFIHLTNQVEQALKVPIEPVSQIENP
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YXLH_BACSU
Sequence: MELQQDLIPQKKTIGALDHAVFLCMVFCFWFSGYIYVPVFSLYLEDLHFSYGAIGIILGSYGVTQILLRFPLGLLSDILFSLRKQLLIAGFGFSVLSSLLFLMFDSFFFVLAARLFAGITASTWVMATILYAHYFNNGNASKAMGIMQFFTVMPQFASIVFCGLAAAHLGRQVPFWMALAASAAGLVICCFIQDPSAPPANRGTIRVNQYIKDTLRLPKLKLFTILSMTAHAVLFITVFGFTPLYMNQLGMGDAELLWVMSAFFLPHAAATLSFVFLRFTSRIAYSVMLISFAVTGVCLLYVPFLAALFTVCITHACIGLALGFVFPLLLSHVVEISSARLKMSVMGFYQSFYALGIFLGPLLAGKIAQLIGLAGVFYGAGSLAFAAFFVMLAQKRNMIN
What are the official names of this protein?
Uncharacterized MFS-type transporter YxlH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYP_NOCSJ
Sequence: MIMRMSSLFVRTLREDPADAEVPSHRLLVRAGYIRRAAPGIYTWLPLGLRVLRKIENVIREEMDAIGAQEMLFPALLPREPYEATNRWTEYGDGIFRLQDRKGADYLLGPTHEEMFTLVVKDLYSSYKDLPLSIYQIQTKYRDEARPRAGLLRGREFVMKDSYSFDVDDAGLDVSYQKHRDAYVRIFDRLGFEYVIVEAMSGAMGGSKSEEFLAKASVGEDTYVRCTLCDYAANVEAVHSPPIPPVPYDDAPAAHAEQTPDTPTIETLVAHLNERFPREDRPWAASDTLKNVVFSVHHPDGATEALAVGLPGDREVDAKRLEAHLGEGVVFEPFGEADFAARPTLAKGYIGPGALGEKKPAGVRYLLDPRVVEGTRWVTGADAAGSHVIDLVAGRDFSGDGLIEVAEVRDGDPCPRGDGGTLETARGIEMGHIFQLGRKYADALDLKVLDEQGKLVTVTMGSYGIGPSRAVAAIAEGTHDELGLAWPREVAPADVHIVATGKDEHVFAAAERIAHELDKQGVEVLYDDRPKVSPGVKFKDAELIGVPTIVVVGKGLAAGTIEVKDRRTGQRQDVPADHLVDRVIAIVRA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGRB_HALH5
Sequence: MLERLALTLAHQVKALNAEETESVEVLTFGFTIILHYLFTLLLVLAVGLLHGEIWLFLQIALSFTFMRVLTGGAHLDHSIGCTLLSVLFITAISWVPFANNYAWILYGISGGLLIWKYAPYYEAHQVVHTEHWERRKKRIAYILIVLFIILAMLMSTQGLVLGVLLQGVLLTPIGLKVTRQLNRFILKGGETNEENS
What is the function of this protein?
May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.
What are the official names of this protein?
Putative AgrB-like protein.
What is the protein family that this protein belongs to?
Belongs to the AgrB family.
Protein: UUPL_HAEIN
Sequence: MEAIEWLENFLLDFQGSIVFISHDRSVIRKMATRIVDLDRGQLQSYLGNYDLYLTTKEENLRVEALQNELFDKRLAQEDVWIRQGIKARRTRNEGRVRALKAMREERRQRREVMGTAKLQLDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGKIRCGTKLEIAYFDQYRADLDPEKIVMDNVADGKQDIEINGVKRHVLGYLQEFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEEILTDYQGTLLIVSHDRQFIDNTATECYLFEGEGRLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEELETKITTLQAEIADPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKKNLADGKA
What is the function of this protein?
Might play a role in ribosome assembly or function; this is missing the first ABC transporter domain compared to paralogs.
What are the official names of this protein?
ATP-binding protein Uup-like.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1195_METTH
Sequence: MDRIRFEQAEKLIRKSCINLKREQGFRDASDGVIDTGKLQEAMMELIDAEEYLYTSLPTHELGGEDASEFCRKLIAAREAIDHILADFGVLERQDPSERIREAARGKLIIVNNSSVKKLLVKAGVEAQNILVAGAPLSVDDMREINPKIPESALRGIEKKIEHLRNDIERKLDALEDVLVVGEPDKSTVLLAARAEELYGADSRLMENIKDLNSEDILELLS
What are the official names of this protein?
Uncharacterized protein MTH_1195.
Protein: TM236_DANRE
Sequence: MLSGKTVKLIVFELLQFACLCIPVFVVMERFASVIRFVKSSDTAYWLVVAASVAYAASVTLFVWVPLKYFMLKTQRFSEVTNWRPVTLAYVILSTLPCFAIIIASSKVQADAAIRFDRLTELPVSLVLFSLICVDIVERIRPLRLTGKASGLDLDLEMPGPVLTHLEQVTSISGHLQANGQDGDASFRSPVSNGSLSGRWEDARTYGLPRTSSSAYLYSHSHSGPFSFLWKRDPRHDLFVSSFMFWLDTVEMVRVAGTNSVFYSGWVFPIYILAYLSLLRVVITPDSPLLALSSILSQDLPFLVVRICLLAVFGYVTPVLYILKNILASISFVYFVFMTKLKLLNRGSMF
What are the official names of this protein?
Transmembrane protein 236.
What is the protein family that this protein belongs to?
Belongs to the TMEM236 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: P19_CRV
Sequence: MERAIQGSDVREQADSECWDGGGGGTTSPFKLPDESPSLHEWRLHHSEESENKDNPLGFKESWSFGKVVFKRYLRYDGAETSLHRALGSWERDSVNDAASRFLGLSQIGCTYSIRFRGTRLTLSGGSGTLQRLIEMAIRTKRTMLQPTPSEREGNVSRRRPEGTEAFKEESE
What is the function of this protein?
Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs).  Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
What are the official names of this protein?
RNA silencing suppressor p19, 19 kDa symptom severity modulator.
What is the protein family that this protein belongs to?
Belongs to the tombusvirus protein p19 family.
Protein: ZG16B_HUMAN
Sequence: MGAQGAQESIKAMWRVPGTTRRPVTGESPGMHRPEAMLLLLTLALLGGPTWAGKMYGPGGGKYFSTTEDYDHEITGLRVSVGLLLVKSVQVKLGDSWDVKLGALGGNTQEVTLQPGEYITKVFVAFQAFLRGMVMYTSKDRYFYFGKLDGQISSAYPSQEGQVLVGIYGQYQLLGIKSIGFEWNYPLEEPTTEPPVNLTYSANSPVGR
What are the official names of this protein?
Zymogen granule protein 16 homolog B.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NEPI_SALPK
Sequence: MNENIAEKFRADGVARPNWSAVFAVAFCVACLITVEFLPVSLLTPMAQDLGISEGVAGQSVTVTAFVAMFSSLFITQIIQATDRRYIVILFAVLLTASCLMVSFANSFTLLLLGRACLGLALGGFWAISASLTMRLVPARTVPKALSVIFGAVSIALVIAAPLGSFLGGIIGWRNVFNAAAVMGVLCVIWVVKSLPSLPGEPSHQKQNMFSLLQRPGVMAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFDVDGLTLVLLSFGIASFVGTSFSSYVLKRSVKLALAGAPLLLALSALTLIVWGSDKTVAAAIAIIWGLAFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAVGGYALDNFGLLSPLALSGGLMLLTALVVAAKVRITPMS
What is the function of this protein?
Involved in the efflux of purine ribonucleosides, such as inosine and guanosine.
What are the official names of this protein?
Purine ribonucleoside efflux pump NepI.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDPA_YERPG
Sequence: MSLDIDQIALHQLIKRDEQTLDVVLRDSLLPTNAVVEEMMAELHRVYSAKSKAYGLFNEQSELADALKRSRKGDEDFLSFSRAATGRLRDELAKYPFAEGGVVLFCQYRYLAVEYLLISVLSSCHSMRVNEQLDLSTTHYLDINRADIVARIDLTEWETNPESTRYLTFLKGRVGRKVSDFFMDFLSAAEGLDTKAQNRGLLQAVDDYCADAELGKNERQAYRQQVYSYCNEQLQAGEEIALQVLAQELPKLGEKDFQQFSAEQGYALEESFPADRGTLRQLTKFAGSGGGLSINFDALLLDERIFWDAATDTLTIKGTPPNLRDQLQRRAGSK
What are the official names of this protein?
Nucleoid-associated protein YpAngola_A1486.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y523_XYLFA
Sequence: MSFSAFELGRFTGRPVRLFVFTRQHLTWRFANSDRDIVSGGFTYLAARIDRSDIQHTTEREKDQITITFPYLLNPAADPLPVTQALGNQWRPYHPVDVIRVVCMVMHVGDTDPPQVEWVGRVIQPRLSDTEMELTCAPHSSIALARNQGAKFQTSCWKTVYSTGLRGCNLSPGAHRVTGRVARLEQLPTDPPQGAHVLVPDMAAHLAPLAGQVATWTYEAQVPHSGTVASVLKFHVRLNNVTAIAVGTVLHWTAADGIAHHGTVTGLFGTVAVLNTTEGITAGSVCHWSVAEARQGTATILQAYHAYDWVSQAAGGSSSGFSWDDASGLHDAHSGTAWSVTYTRRSALVLSDVTGLEEGSSITVALSGSGVSGTLSAVAGLQLTAAHFASAAYSLEGGTLTYTDANGLLIRRSIASHTLGSTTLTLSAGGPNPVVNDAVTVLPTCPRTWDACAARGNTIHFGGAVYRPLHTPDGVSMSWG
What are the official names of this protein?
Uncharacterized protein XF_0523, Protein F14.
Protein: BMPA_BORAF
Sequence: FLSCSGKSGLESGIPKVSLVIDGTFDDKSFNESALNGVKKLKEEFEIELVLKESSTNSYLSDLEGLKDAGSNLIWLIGYKFSDVAKAVSLQNSEMKYAIIDPVYSNEPIPANLVGMTFRAQEGAFLTGYIAAKVSKTGKIGFLGGIEGDIVDAFRYGYEAGAKYANKDIKIFSQYIGSFSDLEAGRSVATKMYSDGIDIIHHAAGLGGIGAIEVAKELGSGHYIIGVDEDQSYLAPNNVITSTTKDVGRSLNLLTSNYLKTNTFEGGKLINYGLKEGVVGFVRNPKMIPFEVEKEIDSLSSKIINKEVIVPYNKESYEKFLKEFI
What is the function of this protein?
Not known; immunogenic protein.
What are the official names of this protein?
Basic membrane protein A, Immunodominant antigen P39.
What is the protein family that this protein belongs to?
Belongs to the BMP lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MNME_BRUA4
Sequence: MSEIASLQDTIFALSSGRLPSGVAVVRISGPKVRFVLETIVGSIPTPRYAAYKLFRSRNGDPIDRGLALFFPGPNSFTGEDCAEFHLHGGKAVVEKLLSEMGELHGCRIAEAGEFTRRAFSNGKMDLTIAEGLADLIAAETEGQRRLALQVASGTQRELYTEWRQRLLRARAFIEAELDFADESDVPGSVSEQVWQSLALLKSEIENHIASGKRASMLRDGLHVVIVGAPNAGKSSLLNFLAGREVAIISEEAGTTRDLLEVKLDLGGIPVYVTDTAGLRETDSSVEKIGIERARARMADADLVLLLEDMNDPIAVASDEIPEALWKIGTKADLNAESADCWTYRISTKTGEGLDQLLTNLQNFAEEQIGQIEDAVPTRQRHINLLRSTVTEIDRAINGTNLPLELRAENMRLASQYLGRITGDVDVEEILDVIFSQFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFBC_METBF
Sequence: MKNQKIIAIYGKGGIGKSSTASNVAAACAEAGKKVMIIGCDPKSDSSITLLRGRRIPTILDLLREGVDIKKEDVVFEGYAGVKCVEAGGPEPGIGCAGRGIIVAIQKLKSISGNLLKEQDLIIYDVPGDIVCGGFVAPVRKGFVNEAYVLTSGEYMPLYAANNICKGLSKIGMPLSGVICNSRNVSREEEIVSKFSEEIGSQLMAFIPKRQVVQDCEREGYSVMEKAPESDIAEIYRKLGKAILENEKRVTADSLSDERLRELTK
What is the function of this protein?
Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes both the six-electron reduction of the tetrahydroporphyrin ring system and the gamma-lactamization of the c-acetamide side chain of Ni-sirohydrochlorin a,c-diamide to yield 15,17(3)-seco-F430-17(3)-acid (seco-F430), the last intermediate in the biosynthesis of the coenzyme F430.
What are the official names of this protein?
Ni-sirohydrochlorin a,c-diamide reductive cyclase complex, component CfbC, NifH homolog component CfbC.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: RNFA_THISH
Sequence: MTEYALILISTVLVNNFVLVKFLGLCPFMGVSRKVETATGMGLATTFVLTLSSVCSYLVNEYLLAPLGLEYLRTIAFILVIAAVVQFTEMVVHKTSPLLYNVLGIFLPLITTNCAVLGVALLNVQEAHGFIESALYGLGAAVGFSLVLVLFASIRERVAVADVPLPFKGNAIALITAGLMSLGFMGFIGLVK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DSRB_ECOL6
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNEAGHQDGIFVEKAE
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: LRPR_STREQ
Sequence: MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKERLLLEVGLGQYEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQVLPADLVELLQQMIAGLEVILPISTTQTAFLCRQATSIKVLRSLEGLLPTLESDFGLALTMFVGNAWYQVAAGTLRECFEEECQLLTAYLKQKSGGKLLTFAEVMLWSILSHQSFPALTRQFHQFLNPQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAYLFLLKY
What is the function of this protein?
Not essential for viability or growth.  Nevertheless, uncontrolled production in E. coli is detrimental to the normal physiology of the bacteria.
What are the official names of this protein?
Leucine-rich protein.
Protein: RS4E_SULIA
Sequence: MAHITRFETPWFLVISKKQYKWTVRPNAGPHPIEKSIPLAVVIRDYLKLAETVREAKHIIFDGKVLVDGKVRKDYKYPVGLMDIVSIPSADLYFRVIPDNVRFMRLSKISADEAHYKYVRIMNKTTVKGGSIQLNLEDGRNILVDKETAKSFKTLMTLKIELPSQNIVDSFIISEGSYAIFVGGKNVGIHGVVKNINLSKFKSRKYSVITLESKDGNTYQTNLMNVMSIGREKSDMRVD
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: DNLJ_THEM4
Sequence: MKNIKEEIERLRKEIEYHNYRYYVLADPIISDEEYDRLLKKLIELEKKYPKFSSPNSPTQKVGGGVISGFEKVEHTTPMLSLDNTYNETEIKEFDNRIKRLLNRNSVEYVCELKIDGISVSIRYENGEFRQAISRGNGIIGDDITENVKKIKSIPLRLFKKYTIEVRGEIFMPIKEFEKYNKIAEEEGLQPFANPRNAAAGTIRQLDSSIVAKRNLDSFIYYIVNPENYSLKTQWEALDFLKKLGFKVNRQSILCKNVECIIDFWKKMTKERKNLDYWIDGLVIKVNNFEFQKILGETSKSPRWAIAFKFPAIKKKTKIIDVELNVGRSGIITPVAIFEPIDLDGTIVKRASLHNFEYIQDKDIRIGDYVYIEKAGGIIPQVVSVVKEKRTGLEKEIKIPKSCPVCNGPVGKLTEDEIAIRCLNPHCPQKLKRHLEIFVSKSAFDISGIGEKIIDKIVDAKLIKDIADIFYLTPFDLAQISGLGQKSIAKILEQIEKSKKTPLNRVIVGLGIPMVGEKTSKILAEKFKNIEKLSSATYDELIKIENIGPEIAKSIVTYFQNEKTKEIINKLKKAGVNLEEKDVKKSDKLKGLTFAITGKLKSYTREEIKKIIEENGGKVSNSVSSKTNFLIAGEEPGSKLEKAKRLNIKIISEEDFLKLISG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RECU_LACP3
Sequence: MTIHYPNGNPYKDGTQFSSQAISRPTIYGGRGMTLEEELNISNQYYRSIDKAVVYKKPTPVQIVKVDYPKRSQAVIREAYFKTPSTTDYNGVYRGFYLDFEAKETKNKASFPLKNFHQHQIEHFRRCLKQSGICFVVIRFATLKRLFVFPAGRLIDCWDRQPDGGRKSIPLKDIVTNGFELHPQLQPVIPFLDGVDWLIETKVGNVRG
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_VARPS
Sequence: MHKLVLIRHGESTWNLENRFTGWTDVDLTETGIEQAKQAGRLLKAEGYDFDVAYTSVLKRATRTLWHTLDELDRTWLPVVHSWRLNERHYGALQGLNKAETAKKYGDEQVLVWRRSYGTPPPPLEADDPRSERSDVRYAKLSPEQVPLTECLKDTVARVLPFWNESMAPAIRTGRRLVVAAHGNSIRALVKYLDGISDDAIVGLNIPNGIPLVYELDDELKPLRHYYLGDAAAAEKAAAAVASQGKG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: GLGB_BACC4
Sequence: MSVINCEEVKRDEFHTEKYYESYNIFGAHVVTEDEIQGVRFTVWAPHAKAMSVVGDFNEWDYEQHKMLQVTEEGIWSLFIPHIEEGEIYKYAIETLAGDVILKADPYAVYAEVRPNTASVVFDIKGYEWNDKNWIRKKKKKSIYKEAMTVYELHFGSWKKKEDGTLYSYREMVEELIPYVVEHQFTHIEIMPLVEHPYDRSWGYQGTGYYAATSRFGTPHDLMHFVDECHKYGIGVILDWVPGHFCKDAHGLYLFDGTPTYEYKDKDVQENPVWGTVNFDLGKREVRNFLISNALFWMRYFHIDGFRVDAVANMLYWNKEGQEQSNEHAVSFLRELNEAVFAEDEDFLMTAEDSTAWPLVTTPTYEGGLGFNYKWNMGWMNDVLKYMECAPEYRKHIHEKMTFSLLYAYSENFILPLSHDEVVHGKKSLLNKMPGDYWDKFAQLRLLYGYFFTHPGKKLLFMGGEFGQFDEWKDLEDLDWNLHDFEMHRYMHDYFKELIALYKRSKPLWQLDHSPEGFQWIDANNNEQSIFSFIRQGDKQEDALVIVCNFTKATYENYKVGVPDFEYYNEILNSDAQQYGGSGQVNKKRLKTILEPYHNQAAHVEITIPPFGVSILRPVKTRKGSKKQDGSKTKVRSNVTSRGKR
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: Y2715_METAR
Sequence: MVRKVKRRVSCLPKATYYKPREIPLCDLEIINLSVEELEAIRLCDLLQIAQDEAADQMGISRKTFWNDLQKARQKVADALVNGKAIQISGGDYVNSGVCKVEFLCQKCNHLWETPCNEKRPENCPKCGSESIYRKGGDGRGKRHTERGFCCPKHGDRAVGDQEESV
What are the official names of this protein?
UPF0251 protein UNCMA_27150.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: QUEF_RICRO
Sequence: MPLSTSLLGKKSTYKDSYDVTLLFKIPRINNRNELGINSNNLPFYGVDVWNTYELSCLNKNGKPWVGVGTFYIPTDSENIVESKSFKLYLNSFNNFVVESVKELERIILQDLSNVTHAKVTGRIFPINTKVEFGVPSGKNIDDLDIVCNNYGAPDNSLIEYEDVLVEEEINSNLLKSNCLVTSQPDWGTIVIKYKGKKLKYDSFLKYLISFRNCNEFAEQCAERIFTDIQNAISPDFLSIYIVYARRGGIDICPYRSTDKNYTLPSDKRFIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_MICLU
Sequence: MVADQAVLSSWRSVVGSLEDDARVSARLMGFVYLAQPQGLIGNTLLLAVPNETTRETLQGTQVADALTDALTQEFREEILLAISIDANLQPPRTPSSEARRSSLAGGPSGAAAPDVELPPAATAATSRRAVAEELPGFRIEPPADVVPAANAAPNGNGKPTPAPPSTSAETSRLNDRYHFETFVIGSSNRFAHAAANAVAEAPAKAYNPLFIYGESGLGKTHLLHAIGHYARRLYPGLRVRYVNSEEFTNDFINSIRHDEGASFKQVYRNVDILLIDDIQFLADKEATVEEFFHTFNTLYNNNKQVVITSDLPPKQLSGFEDRLRSRFEWGLITDIQPPDLETRIAILRKKAEAEGLVAPPEALEYIASRISTNIRELEGALIRVTAFASLNRQTVDIELAEHVLKDLITDETAHEITPELILHATGEYFNLTLEELTSKSRTRTLVTARQIAMYLLRELTEMSLPKIGQVLGGRDHTTVIHADRKIRELMAERRTIYNQVTELTNEIKRKQRGA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_FRATF
Sequence: MNKIAIYPGTFDPITNGHVDLVERALNIFDEIVVAVSTAYGKNTLFDIRIREQMIKEVFKDNQRVKVVSFQGLLVDTAVKHNACAIVRGLRAVSDFDYEFQMSSMNNKLNSDIQTIFLTPSEKFSCISSTLVRAVAIHNYKRVDEFVPECVFREIKLKYSKE
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.