PharMolix/UniProtQA huggingface dataset:
Protein: TPIC_SECCE
Sequence: MAARRPSPPPASPPPPRPRSTTTTRTTSSASAAPAAAQRLVAMAGSGKFFVGGNWKCNGTKESISKLVSDLNAATLESDVDVVVAPPFIYIDQVKSSLTDRIEVSAQNTWIGKGGAFTGEISAEQLVDIGCQWVILGHSERRHVIGEDDEFIGKKAAYALSQNLKVMACIGELLEEREAGKTFDVCFKQMKAFADNITDWTNVVIAYEPVWAIGTGKVASPEQAQEVHAAVRDWLKTNVSADVASTVRIIYGGSVNAANCAELAKKEDIDGFLVGGASLKGPDFATICNSVTSKKVTA
What are the official names of this protein?
Triosephosphate isomerase, chloroplastic, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SSBR_ECOLX
Sequence: MSARGINKVILVGRLGNDPEVRYIPNGGAVANLQVATSESWRDKQTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWDDNGITRYITEILVKTTGTMQMLGSAPQQNAQAQPKPQQNGQPQSADATKKGGAKTKGRERKAAQPEPQPQTPEGEDYGFSDDIPF
What is the function of this protein?
May contribute to the conjugative processing of DNA.  It has a functional relationship with Psi (plasmid-mediated sos inhibition) proteins.
What are the official names of this protein?
Plasmid-derived single-stranded DNA-binding protein, SSB, Helix-destabilizing protein.
Protein: RL17_PROA2
Sequence: MRKVKSARKLGRTASHRKATLANLSTQLLLHKRIETTEAKAKETRKHVEKIITKAKKGTVHAQRIIFKTIRDKSAIRELFEDIIGRIGDRNGGYTRIIKLAPRYGDAAKMAVIELVDYAEMPAEQPKAATTDRSKRVKGSKKKAVAEGTSAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GLHA_MERUN
Sequence: MDYDRRYAAVILVVLSMFLHILHSLPDGDFIIQGCPECKLKENKYFSKGGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKSFTKATVMGNARVENHTECHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
What are the official names of this protein?
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: TORD_SALPC
Sequence: MIKQPALAQEQYACVYAWLALLFFREVDDEGLIQLQSAEIADWLALLKRQPALAASVALLEQKIAALSLRQDAQLELAADFCGLFLMTDKKSALPYASQYPQQEPGMIKHLLLEAGMEVNDDFKEPADHLAIYLELLSHLHFSLGESFQQRRMNKLRQKTLSSLLEWLPEFTNNCLKHDPYGFYAALSQLLLAIVRFDDGKEDLSIVAAE
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4JQ_SINFN
Sequence: MSLLMAHRKSKSSQRKLRNRSSSLTPQKRRIRASKGSHDTILSIRNETSSLEALSRTIQWTLARYKYHRYLVSLSPRTPSQLPDYVLAANDSLENAMKWQIASISAVGGKIASHNKNTYTSIDQITDYSASLERANAEIRTCMWSFSSASQALFSLARTKGLDAQRRWMQGSLYVANPSISNIILYSKGIASEGDRHPSDVLEVLNRFIFSKFADEELNLLLYYLTFNPLLNVEVASKLSPLLLYFPVVDQYEFLANLFTSDQSLSKPDVLPFGRDFVEILSSTGDWRASPKAALAERVEPSRFTIPLLNRWCGYLLDSIGILDGVSSAPDREFDIALANEFFHQPQSPRAYLASSIFAMKSAQTLADVKSALYKREIANVHFEKVEQQIAPPDQRFIDYSFAAVAAEVGISESVYENRELFRIACICGISEGRTLDTLILLCEYTNADPFGSSYFPADLFSASVTEDEVARIGHDPRVAIGLSRVAASLGDEGQNLVYIAVEQHLNVRGMSKPSEIVADSAVDVAFLREACTSSSLRQSLEFLSKAEMEDERIQVLFNLAQVDPANEDDYIEEVHTIIGQQTIEELLQRFHVGKVQCDEQALSTWALIELSPKFNRLKDFIDAGLPPVEKDADIQFIAHLTSGKSETFTFKVPNNESLDIARTILAELNSKYALDPRYGVDSYLSLGMRHGAVEAHLQSPLSAENILTAKEPLGYPDDCFWTRYFIDNGFECYGEKIGPVLATFSEKFDNKLEAIKNDLLQVRRPDKPEGLIVADWSEASVLSACARFAEVPDFEAFIAEFTLIFWANVEGNLAAAREFIENVLSNELNELLDELEANVRQATGQQRLAPFSDALMRARQELGNAVNDVSTWHNVARSTDVEPLGLVEIISAAQKIVCRLYPDFEPRVTFSGDTGITVTYSLHILIEVFKALFTNVYAHSEVENPAVDVHMAMTVEDALDVEFVSDCNDMGKAERAALDANEKIRTGEYEKKLPKEGGSGLAKVARSTLRDGKPNTVISVDHSTCKFHVKMAFKIIQI
What are the official names of this protein?
Uncharacterized protein y4jQ.
Protein: TIM44_RAT
Sequence: MAAAALRGGWCRCPRRCLGSGIQFLSSHNLPRGGSSYQISRPGGELTLTKSYSSGSRKGFLSGLLDNIKQELAQNKEMKESIKKFRDEAKKLEESDALQEARRKYKTIESETVRTSEAIKKKLGELTGTVKESLDEVSKSDLGRKIKEGVEEAARTAKQSAESVSKGGEKLGKTAAFKAISQGVESVKKEIDESVLGHTGTYRRPERLRKRTEFAGAKFKESKVFEANEEALGVVLHKDSKWYQQWKDFKDNNVVFNRFFEMKMKYDESDNVLIRASRALTDKVTDLLGGLFSKTEMSEVLTEILRVDPTFDKDRFLHQCETDIIPNILEAMISGELDILKDWCYEATYNQLAHSIQQAKALGLQFHSRILDISNVDLAMGKMMEQGPVLIVTFQAQLVMVIKNPKGEVFDGDPDKVLRMLYVWALCRDQEELNPYAAWRLLDISASSTEQIL
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity).  Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM44.
What is the protein family that this protein belongs to?
Belongs to the Tim44 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Mitochondrion matrix.
Protein: OBG_ACAM1
Sequence: MRFIDQTEIFVKAGDGGDGMVAFRREKYVPAGGPAGGNGGRGGSVILQASTQLQTLLDFKYKHQFVAEDGKRGGPKNLTGASGQDRLIEVPCGTVIYDADSMTLLGDLTTNGQTLTVAQGGKGGLGNKHFLSNRNRAPEHALPGLPGEEFRLHLELKLLAEVGIIGLPNAGKSTLISVLSAARPKIADYPFTTLIPNLGVVPRATGDGTVFADIPGLIEGAHEGVGLGHDFLRHVERTRLLVHLVDATAEDPEQDYQTIQKELSAYGQGLQNRPQLLVLNKIDAMDSEQLLEKQACLEQMSGSPVYLISAVAQQGLDTLLQQVWEELDRLPNDLQEAPIPVLDSPILRET
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BZNB_PSEFL
Sequence: MAMITGGELVVRTLIKAGVEHLFGLHGAHIDTIFQACLDHDVPIIDTRHEAAAGHAAEGYARAGAKLGVAGHGGRGIYQCGHAHCQRLAGSQGRCIPHPGSGALRDDETNTLQAGIDQVAMAAPITKWAHRVMATEHIPRLVMQAIRAALSAPRGPVLLDLPWDILMNQIDEDSVIIPDLVLSAHGARPDPADLDQALALLRKAERPVIVLGSEASRTARKTALSAFVAATGVPVFADYEGLSMLSGLPDAMRGGLVQNLYSFAKADAAPDLVLMLGARFGLNTGHGSGQLIPHSAQVIQVDPDACELGRLQGIALGIVADVGGTIEALAQATAQDAAWPDRGDWCAKVTDLAQERYASIAAKSSSEHALHPFHASQVIAKHVDAGVTVVADGALTYLWLSEVMSRVKPGGFLCHGYLGSMGVGFGTALGAQVADLEAGRRTILVTGDGSVGYSIGEFDTLVRKQLPLIVIIMNNQSWGATLHFQQLAVGPNRVTGTRLENGSYHGVAAAFGADGYHVDSVESFSAALAQALAHNRPACINVAVALDPIPPEELILIGMDPFA
What is the function of this protein?
Cleavage of benzoin-anisoin acyloin linkage.
What are the official names of this protein?
Benzaldehyde lyase, Benzoin aldolase, BL, BZL.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: IPAC_SHIDY
Sequence: MEIQNTKSTQILYTDISTKQTQSSSETQKSQNYQQIAAHIPLNVGKNPVLTTTLNDDQLLKLSEQVQHDSEIIARLTDKKMKDLSEMSHTLTPENTLDISSLSSNAVSLIISVAVLLSALRTAETKLGSQLSLIAFDATKSAAENIVRQGLAALSSSITGAVTQVGITGIGAKKTHSGISDQKGALRKNLATAQSLEKELAGSKLGLNKQIDTNITSPQTNSSTKFLGKNKLAPDNISLSTEHKTSLSSPDISLQDKIDTQRRTYELNTLSAQQKQNIGRATMETSAVAGNISTSGGRYASALEEEEQLISQASSKQAEEASQVSKEASQATNQLIQKLLNIIDNINQSRSSTASQIAGNIRA
What is the function of this protein?
Associated with the entry of the bacteria into colonic epithelial cells.
What are the official names of this protein?
Invasin IpaC, 42 kDa antigen.
What is the protein family that this protein belongs to?
Belongs to the invasin protein C family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted through a specialized type-III system.
Protein: PYRF_STRSV
Sequence: MREERPIIALDFPSFDDVKDFLEHFPEDEKLYVKIGMEFFYAIGPEIVHYLKGLGHSIFLDLKLHDIPNTVRSAMSVLGTFGIDMVTVHAAGGVEMMSEAKKVLGDKAKLVAVTQLTSTSEEDMRDCQNIQTTVQESVVNYARKAKEAGLDGVVCSAQEVELIKAATADDFLCVTPGIRPAGSEIGDQKRVMTPQEAHQIGSDYIVVGRPIIQAENPWDAYHEIKKQWNS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: TRMD_FINM2
Sequence: MKFIILTLFPESFDYLKSYGVIGKAIQNNLIELEVVNIRDYTKNKHKKVDDEIYGGGAGMLMTCQPIYDCLEDVNKNQSKVVFMSPQGKVLNQQKCIELSKEKEIVILCGHYEGVDSRIINHYCDEEISIGDYVMTGGELGAMVLIDCVSRMINDVLGNDESYKTDSHYNLLLQEDSYTRPRVFNGYEVPEVLLSGNHEKIEQWREKSRLNNTKLKREDIYQKYLKEKNQGGS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y921_GEODF
Sequence: MPSFDIVSKVDMQEVDNAVNQAVKEIAQRYDFKGSKSEVTLEKDAIKVLTEDDFRLKAIIDILQSKFIKRGISAKALQYGKVENASGSMVRQVIDVQQGVSKEKGKEINNVIKETKLKVQSQIQDDQVRVTGKNIDDLQQVIQLLKGKDLGLDLQFVNFRQ
What are the official names of this protein?
UPF0234 protein Geob_0921.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: 1A1C_SOYBN
Sequence: MGLMDVDQTQLLSKMVIGDGHGEASPYFDGWKAYDENPFHPKENPNGVIQMGLAENQLTSDLVEDWILNNPEASICTPEGINDFRAIANFQDYHGLPEFRNAVAKFMGRTRGNRVTFDPDRIVMSGGATGAHEVTTFCLADPGDAFLVPIPYYPGFDRDLRWRTGIKLVPVMCDSSNNFKLTKQALEDAYEKAKEDNIRVKGLLITNPSNPLGTVMDRNTLRTVMSFINEKRIHLVSDEIYSATVFSHPSFISIAEILEEDTDIECDRNLVHIVYSLSKDMGFPGFRVGIIYSYNDAVVHCARKMSSFGLVSTQTQYLLASMLNDDEFVESFLVESAKRLAQRHRVFTGGLAKVGIKCLQSNAGLFVWMDLRQLLKKPTLDSEMELWRVIIDEVKINVSPGSSFHCTEPGWFRVCYANMDDMAVQIALQRIRNFVLQNKEIMVPNKKHCWHSNLRLSLKTRRFDDIMMSPHSPIPQSPLVKATI
What is the function of this protein?
Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate synthase, ACC synthase, S-adenosyl-L-methionine methylthioadenosine-lyase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: COFI_SCHPO
Sequence: MSFSGVKVSPECLEAFQELKLGKSLRYVVFKMNDTKTEIVVEKKSTDKDFDTFLGDLPEKDCRYAIYDFEFNLGEGVRNKIIFISWSPDVAPIKSKMVYSSSKDTLRRAFTGIGTDIQATDFSEVAYETVLEKVTRK
What is the function of this protein?
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner.  It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin.  Binding to F-actin is regulated by tropomyosin.  It is the major component of intranuclear and cytoplasmic actin rods.  Required for accumulation of actin at the cell division site via depolymerizing actin at the cell ends.  In association with myosin II has a role in the assembly of the contractile ring via severing actin filaments.  Involved in the maintenance of the contractile ring once formed.  In association with profilin and capping protein, has a role in the mitotic reorganization of the actin cytoskeleton.
What are the official names of this protein?
Cofilin, Actin-depolymerizing factor 1.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Note=Septum. Throughout the cytoplasm (but not on the cytoplasmic cables) and major component of the cortical actin cytoskeleton.
Protein: LITAF_HUMAN
Sequence: MSVPGPYQAATGPSSAPSAPPSYEETVAVNSYYPTPPAPMPGPTTGLVTGPDGKGMNPPSYYTQPAPIPNNNPITVQTVYVQHPITFLDRPIQMCCPSCNKMIVSQLSYNAGALTWLSCGSLCLLGCIAGCCFIPFCVDALQDVDHYCPNCRALLGTYKRL
What is the function of this protein?
Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation (PubMed:23166352).  Plays a role in targeting endocytosed EGFR and ERGG3 for lysosomal degradation, and thereby helps down-regulate downstream signaling cascades (PubMed:23166352).  Helps recruit the ESCRT complex components TSG101, HGS and STAM to cytoplasmic membranes (PubMed:23166352).  Probably plays a role in regulating protein degradation via its interaction with NEDD4 (PubMed:15776429).  May also contribute to the regulation of gene expression in the nucleus (PubMed:10200294, PubMed:15793005).  Binds DNA (in vitro) and may play a synergistic role with STAT6 in the nucleus in regulating the expression of various cytokines (PubMed:15793005).  May regulate the expression of numerous cytokines, such as TNF, CCL2, CCL5, CXCL1, IL1A and IL10 (PubMed:10200294, PubMed:15793005).
What are the official names of this protein?
Lipopolysaccharide-induced tumor necrosis factor-alpha factor, LPS-induced TNF-alpha factor, Small integral membrane protein of lysosome/late endosome, p53-induced gene 7 protein.
What is the protein family that this protein belongs to?
Belongs to the CDIP1/LITAF family.
Protein: ITPA_CRYNJ
Sequence: MTSFVFVTGNANKLREVKAILAAGDSGIEVTSQSVDVPELQGTTQEIAIAKCKVAAEKLGTACVTEDTALCFEALNGLPGPYIKDFLANIGHEGLNTLLNGFPTTRATALCTFAYSPGPGEEPILFEGRTEGNIVPARGSKVFGWDPIFQPLEGGGRTYAEMDGEEKNKISHRYRALEKLRAYLSEQAK
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYSG1_AERS4
Sequence: MDYLPIFCRLDNKPVLLVGGGEVAERKARLLLDAGARLTVVSPALDPELAALATSGTIDWLAAEFEPAHLTGKWLVVAATDRREVNALVYQSANQAGIFANVVDDPKRSSFIMPSIIDRSPLMVAISSGGKAPVLARLLREKLEALLPQHLGAVAAFAGGLRARVKARFASMGERRQFWERLLSADRLGQALARGDKASANQLADTLFAEETGAKGEVILVGAGPGDPGLLTLHALRHMQQADLVVYDQLVSDEVMALVRRDARRIFVGKQAGNHCVPQEGINQLLLEEASKGQRVVRLKGGDPFIFGRGGEELETLVGSGVGFQVVPGITAASGCAAYAGIPLTHRDHAQSVRFVTAHGKGGTQDLDWPLLARDQQTLVFYMGLSSCATIRQKLTAHGKAGTTPVALIERGTQLNQRVIRGTLDQLPELAVGVESPALIMVGSVVTLADKLAWFGQTNHGVQAAALA
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: HOA2_MYCSK
Sequence: MTETVSRPHATEGAALYIQDVTLRDGMHAMRHRISPEKVAAIAGALDTAGVDAIEVTHGDGLAGHSLTYGPGSNTDWEWIEAAADVVHRAKLTTLLLPGVGTVRELEHAYKLGVTSVRVATHCTEADVSAQHIGTARELGMDVSGFLMMSHLAEPSHLAAQAKLMESYGAHCVYVTDSGGRLTMGSVRDRVRAYRDVLDAGTQIGIHAHQNLSLSVANTVVAVEEGVTRVDASLAGHGAGAGNCPIEPFIAVADLHGWKHNCDLFGLQDAADDIVRPLQDRPVQVDRETLTLGYAGVYSSFLRHAEAAAKQYGLDTRAILLAVGERGLVGGQEDLIPDIALDLQQNLRR
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: LIAS_ORYSJ
Sequence: MHGRRHLAASLARALTYAPSRSISSTPSLLQTLDPSTPSPAAAPPTAGRLAELRQRLQADAPSLGDFTYSVEVGTRKKPLPKPKWMKETIPGGAKYAGIKAKLRELKLHTVCEEARCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPPPDPDEPSNVAQAIASWGLEYIVITSVDRDDLPDQGSGHFAETVQKLKVLKPEMLIEALVPDFRGDPACVEKVATSGLHVFAHNIETVEELQRNVRDHRANFKQSIDVLKLAKEYAPAGTLTKTSIMLGCGETPDQVISTTEKVRAAGVDVMTFGQYMRPSKRHMPVSEYVTPEAFERYRSLGVDMGFRYVASGPMVRSSYKAGEFYIKAMIEADRAKATTAI
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YXJB_BACSU
Sequence: MKRTVDFSMFRCPLCDSSMDAASGKSLICTERGHTFDLSRHGYVNFLTKPVKTSYGAELFEARSRLIGECGFFDPLHDAIAELISHPKSGHEAFTILDSGCGEGSHLNALCGFDYAGKAAIGTGIDLSKDGILKASKAFKDLMWAVADVARAPFHDRQFDVVLSIFSPSNYAEFHRLLKNDGMLIKVVPRSDYLIELRQFLYTDSPRRTYSNTAAVERFTANAAHSRPVRLRYVKTLDQQAIHWLLKMTPLAWSAPKDRVSLLKEMKSADITVDVDILIGMK
What are the official names of this protein?
Putative 23S rRNA (guanine-N(1)-)-methyltransferase YxjB.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmA family.
Protein: GCS2_LEGPH
Sequence: MRLLSFKKSKIVSIGTELEFQIIDCSSLSLVSRSKELMRALKDMRYRDQIKPEITQSMIEINSSIHQSAKEMYDELLELQKILVETAASIDIAFCGGGTHPFQQWTMQKIFPSKRFKKKFNQYRYLSKRATVFGQHIHIGCPTGDDAIYLTHALARYVPHFIAISASSPFYLGINTNYCSSRSTIFNAFPLSGVIPYLRNWQEFSDYYRKMYRWKIIENMKDFYWDIRPKPELGTIEIRVCDTPLTLRKSILITAYIQALALYLLEEKSVQLSHDLYYVYNYNRFQASRHGLEGELTVTDKDRPIPIMDDILETIKKIEQYINGLGNSEYIEELYSDVINKQNDSVLINKIYKQDGSFSKLVAAQCELWLSDSKDRKWMTQPS
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: MRAY_ANOFW
Sequence: MNEKVILFTAGLAFIITVVLSPIFIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGLMILLSLSITTWLMSDIFFERTAHTYMLLFVTVGYGLLGFIDDFIKVVMKRNLGLTSKQKLAGQLLIALIFYFFFQHYSMSTVVSIPGTDVSLDLGVAYVLLIIFMLVGGSNAVNLTDGLDGLLAGTAAIAFGAYAVLAWNQGQYDVAIFSVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGAIVTIAILTKLEILLVIIGGVFVIETLSVIIQVISFKTTGKRVFRMSPLHHHYELIGWSEWRVVVTFWAVGLLFAILGIYIEVWV
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRC_MYCLE
Sequence: MSVLLRGVRLYGEGEQVDVLVEGEQIANIGAGIDIPDTADVIDAIDQVLLPGLVDLHTHLREPGREYAEDIETGSAAAALGGYTAVFAMPNTTPVADSPVVTDHVWRRGQQVGLVDVHPVGAVTVGLAGAELTEMGMMAAGAAQVRIFSDDGNCVHNPLVMRRALEYATGLGVLIAQHAEEPRLTVGAVAHEGPTAARLGLSGWPRAAEESIVARDALLARDAGARVHICHASTAGTVEILKWAKEQGISITAEVTPHHLLLDDSRLASYDGVNRVNPPLRETADAVALRQALADGIIDCVTTDHAPHADHEKCVEFSAARPGMLGLQTALSVVVHTMVVPGLLSWRDVAQVMSENPARIAGLPDHGRPLEVGEPANLTVVDPDVTWTVTGDGLASRSANTPYEAMTLPATVTATLLRGKVTARGQKSPV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: ATPB_YERPE
Sequence: MATGKIIQVIGAVVDVEFPQDAVPKVYNALEVEGTTEKLVLEVQQQLGGGVVRCIAMGSSDGLSRGLKVTNLEHPIEVPVGKATLGRIMNVLGEPIDMKGPIGEEERWAIHREAPSYEELASSQDLLETGIKVMDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEDDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKFVSLKDTIRGFKGIMNGDYDHLPEQAFYMVGTIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DXR_CUPPJ
Sequence: MHRITILGATGSIGESTLDVVRRHADRYAVHALTAHRQVQKLAASCIEFRPARAVVGTSEAAAELEALLRMAGVKTEVSHGEAALESVASDAQTDSVMAAIVGAAGLRPTLAAARAGKRVLLANKEALVMSGRIFMDAVREHGATLLPIDSEHNAIFQCLPANDQRYRAGVAKVVLTASGGPFRTRDPATLHDITPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAHWLFGAPAEHIEVLIHPQSIVHSMVAYRDGSVLAQLGNPDMRTPIAYGLAYPERIDAGVSPLDLTLAGALNFEKPDLVRFPCLALAFDALRAGGVAPAVLNAANEVAVEAFLQGGIRFTDIARIVGNVLEKAPHGAADSLECVLEADQLARQSARACLQDVTTSAVR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: VG50_BPMB2
Sequence: MTNWGPTGELVYNRTYSRTKPDGSKETWPETVRRVVDGNLALVDERYHLPGERADLIRLMEEFKILPGGRHLWASGVKNAQHLFNCWVSGWTEKPSDHFEFTFMRLMEGGGVGANYSNRFIDYGPVQQELYVHIVCDPDHPDYEAMKEAGVLSTEYDPDWAGAFVIEDSREGWAAALVDLIDTHYRDEVSHFQRVYDVSRVRQFGAKLKTFGGTASGPLPLARMLIDVCEILSEIATEGGQLTGIAAMEIDHAIAQCVVAGGVRRSARMSMMHWKDPQVYEFLRIKQDTGSHWTTNISLEVDDEFWVAVEEGWAGPNNRILRELTEGMVANGEPGFWNSSLSNVGEPNEVVCTNPCGEITLEPWEPCNLGHVNLAAFAHGNGSYDITGLYRAHRLVTRFLMRATFSPVADPKSREVLDRNRRIGVGHLGVASFLALCGWKYSEARTNEEFKWLLRSLAEEVDHAATQFAHQLRIPVPVKKRTVAPTGTIAKMPGVSEGIHPIFSRYFIRRVRLSMSDPDQTRMLADYGRQGYEVEDDLYAKFTGVVSIPTQDTLVAEVIEHYGQDSESLVESAADLSLNELLGFQALYQTIWADNAVSFTANVDPETYNADDVRQQLRLFGGLLKGATIFPEASMPQAPYERITKEQYEQATAKAVADGVDEDCANGACPIR
What are the official names of this protein?
Putative adenosylcobalamin-dependent ribonucleoside-triphosphate reductase, Gp50.
What is the protein family that this protein belongs to?
Belongs to the class II ribonucleoside-triphosphate reductase family.
Protein: RIMP_BRASB
Sequence: MTEPTFAAADTDLLTEPRLVVEPGVAARVAAVAEPVLQGMGYRLVRIRISGEAGCTVQVMAERPDGTMQIEDCEAVSRALSPVLDIADPIDRAYRLEISSPGIDRPLVRRTDFERHIGHLVKIEMAVAHQNRKRFRGIITGLDGDGVCITRDDVAKDQDPSVVLPMTDIGDAKLVLTDELIAESMRRGKAAEREKKRDLGLAPPLAPHAKPAAQAKPKPKLKDGQAAKKPLPTNTKKHRLAADRARRGEIDPD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.