PharMolix/UniProtQA huggingface dataset:
Protein: FUR_STAAS
Sequence: MNTNDAIKILKENGLKYTDKRKDMLDIFVEEDKYINAKYIQQVMDENYPGISFDTIYRNLHLFKDLGIIENTELDGEMKFRIACTNHHHHHFICEKCGDTKVIDYCPIDQIKLSLPGVNIHKHKLEVYGVCESCQD
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCR_ENT38
Sequence: MRLTSKGRYAVTAMLDVALNSETGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDAGSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQQSHETQRTTRAQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: SGPP1_HUMAN
Sequence: MSLRQRLAQLVGRLQDPQKVARFQRLCGVEAPPRRSADRREDEKAEAPLAGDPRLRGRQPGAPGGPQPPGSDRNQCPAKPDGGGAPNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNWPLYCLFCFGTELGNELFYILFFPFWIWNLDPLVGRRLVVIWVLVMYLGQCTKDIIRWPRPASPPVVKLEVFYNSEYSMPSTHAMSGTAIPISMVLLTYGRWQYPLIYGLILIPCWCSLVCLSRIYMGMHSILDIIAGFLYTILILAVFYPFVDLIDNFNQTHKYAPFIIIGLHLALGIFSFTLDTWSTSRGDTAEILGSGAGIACGSHVTYNMGLVLDPSLDTLPLAGPPITVTLFGKAILRILIGMVFVLIIRDVMKKITIPLACKIFNIPCDDIRKARQHMEVELPYRYITYGMVGFSITFFVPYIFFFIGIS
What is the function of this protein?
Specifically dephosphorylates sphingosine 1-phosphate (S1P), dihydro-S1P, and phyto-S1P.  Does not act on ceramide 1-phosphate, lysophosphatidic acid or phosphatidic acid (PubMed:16782891).  Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway (PubMed:12815058, PubMed:11756451, PubMed:16782891).  Regulates the intracellular levels of the bioactive sphingolipid metabolite S1P that regulates diverse biological processes acting both as an extracellular receptor ligand or as an intracellular second messenger (PubMed:11756451, PubMed:12815058, PubMed:16782891).  Involved in efficient ceramide synthesis from exogenous sphingoid bases.  Converts S1P to sphingosine, which is readily metabolized to ceramide via ceramide synthase.  In concert with sphingosine kinase 2 (SphK2), recycles sphingosine into ceramide through a phosphorylation/dephosphorylation cycle (By similarity).  Regulates endoplasmic-to-Golgi trafficking of ceramides, resulting in the regulation of ceramide levels in the endoplasmic reticulum, preferentially long-chain ceramide species, and influences the anterograde membrane transport of both ceramide and proteins from the endoplasmic reticulum to the Golgi apparatus (PubMed:16782891).  The modulation of intracellular ceramide levels in turn regulates apoptosis (By similarity).  Via S1P levels, modulates resting tone, intracellular Ca(2+) and myogenic vasoconstriction in resistance arteries (PubMed:18583713).  Also involved in unfolded protein response (UPR) and ER stress-induced autophagy via regulation of intracellular S1P levels (PubMed:20798685, PubMed:18583713).  Involved in the regulation of epidermal homeostasis and keratinocyte differentiation (By similarity).
What are the official names of this protein?
Sphingosine-1-phosphate phosphatase 1, SPPase1, Spp1, hSPP1, hSPPase1, Sphingosine-1-phosphatase 1, Sphingosine-1-phosphate phosphohydrolase 1, SPP-1.
What is the protein family that this protein belongs to?
Belongs to the type 2 lipid phosphate phosphatase family.
Protein: POLS_IPNVS
Sequence: MNTNKATATYLKSIMLPETGPASIPDDITERHILKQETSSYNLEVSESGSGVLVCFPGAPGSRIGAHYRWNANQTGLEFDQWLETSQDLKKAFNYGRLISRKYDIQSSTLPAGLYALNGTLNAATFEGSLSEVESLTYNSLMSLTTNPQDKVNNQLVTKGVTVLNLPTGFDKPYVRLEDETPQGLQSMNGAKMRCTAAIAPRRYEIDLPSQRLPPVPATGTLTTLYEGNADIVNSTTVTGDINFSLAEQPADETKFDFQLDFMGLDNDVPVVTVVSSVLATNDNYRGVSAKMTQSIPTENITKPITRVKLSYKINQQTAIGNVATLGTMGPASVSFSSGNGNVPGVLRPITLVAYEKMTPLSILTVAGVSNYELIPNPELLKNMVTRYGKYDPEGLNYAKMILSHREELDIRTVWRTEEYKERTRVFNEITDFSSDLPTSKAWGWRDIVRGIRKVAAPVLSTLFPMAAPLIGMADQFIGDLTKTNAAGGRYHSMAAGGRYKDVLESWASGGPDGKFSRALKNRLESANYEEVELPPPSKGVIVPVVHTVKSAPGEAFGSLAIIIPGEYPELLDANQQVLSHFANDTGSVWGIGEDIPFEGDNMCYTALPLKEIKRNGNIVVEKIFAGPIMGPSAQLGLSLLVNDIEDGVPRMVFTGEIADDEETIIPICGVDIKAIAAHEQGLPLIGNQPGVDEEVRNTSLAAHLIQTGTLPVQRAKGSNKRIKYLGELMASNASGMDEELQRLLNATMARAKEVQDAEIYKLLKLMAWTRKNDLTDHMYEWSKEDPDALKFGKLISTPPKHPEKPKGPDQHHAQEARATRISLDAVRAGADFATPEWVALNNYRGPSPGQFKYYLITGREPEPGDEYEDYIKQPIVKPTDMNKIRRLANSVYGLPHQEPAPEEFYDAVAAVFAQNGGRGPDQDQMQDLRELARQMKRRPRNADAPRRTRAPAEPAPPGRSRFTPSGDNAEV
What is the function of this protein?
Structural peptide 3 is a small peptide derived from pVP2 C-terminus.  It is not essential for the virus viability, but viral growth is affected when missing (By similarity).
What are the official names of this protein?
Structural polyprotein, PP.
What are the subcellular locations of this protein?
[Capsid protein VP2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein VP3]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 1]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 3]: Virion. Host cytoplasm.
Protein: URK_CLOBJ
Sequence: MKRPVLIGITGGTGSGKSTVAKEIYNKFDEACIAMIEQDSYYKDQSSMPFEERCKKNYDHPDAFDNELLIDHLKNLIDLNVIEKPIYDFEAHNRKEETIKVKPRDIIIVEGILVLQDPRVRELLDIKIYVDTDADVRIIRRLLRDINERGRTVDSVINQYLTVVRPMHMQFIEPSKRYADIIIPEGGHNRVAVDMMVANIKHLLQE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOTA_AQUAE
Sequence: MDVGTIIGIIAAFLLILISILIGGSITAFINVPSIFIVVGGGMAAAMGAFPLKDFIRGVLAIKKAFLWKPPDLNDVIETIGEIASKVRKEGILALEGDIELYYQKDPLLGDMIRMLVDGIDINDIKATAEMALAQLDEKMSTEVAVWEKLADLFPAFGMIGTLIGLIQMLRNLNDPSALGPGMAVALITTLYGAILANAFAIPVANKLKKAKDMEVLVKTIYIEAIEKIQKGENPNVVKQEAAIMLGVELPEEV
What is the function of this protein?
MotA and MotB comprise the stator element of the flagellar motor complex.  Required for rotation of the flagellar motor.  Probable transmembrane proton channel (By similarity).
What are the official names of this protein?
Motility protein A, Chemotaxis protein MotA.
What is the protein family that this protein belongs to?
Belongs to the MotA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EF1B_XENTR
Sequence: MGFGDLKSPAGLKVLNEFLADKSYIEGYVPSQADVAVFDALSGAPPADLFHALRWYNHIKSYEKQKSSLPGVKKPLGNYGPVNIEDTTGSTAKDTKEEDDDDDIDLFGSDDEEENEESKRVREERLAQYEAKKSKKPALIAKSSILLDVKPWDDETDMAKLEECVRSIQMEGLVWGASKLVPVGYGIKKLQIQCVVEDDKVGTDVLEENITAFEDFVQSMDVAAFNKI
What is the function of this protein?
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: LNBA_ASPFN
Sequence: MMLSNLLPSPEPLGADEYGLCVASNLGLGQLFYRQVRQSPSSIAVVDDESSITYGQLHAWAVRLAAKLSQEGFVKEEAVGIVVQHGVADVVAQMAVIYAGGSCAPMDPTMRDQQIGQRLQRLNSRFILVDQSNRGRDLQFQQIVLEKHLPLTITDLCEENEFPVTTDLSHRTHLIHTSGTTSEPKAVQIAARSILQVVFHAPFEPLAVEDVVAHANNSSFDVSLFDIWAPLLRGARIAILKKMVLLDLVVLAEHIDRLGITVMATTTALLNLAASTLPTAFSKLRICFIGGEAANVSAIETVLRKGPPKMLINAYGPTECCIFCLAHRVTPKDIQMGSVSIGMPIGHTIAYIADESGCAANEGELWIGGAGVSPGYINEPEKNAKSFPTIMMPSGEAARFYRTGDIVRRRDDGQIDYVGRVDHQIKVRGFRIELEAIETSLLQTGLFAEVAAMGIQSPHQGAGSVLVAYATPKDPAHPPEISKALKILQDILPEYMIPQLQLIEKMPLNSHAKVDRKGLKQLFCQRSTSLLKPVPKLPNTLCQDTQTVLASLWATILATPKSEYKESDDFFVLGGTSLQASLLISQIRQVFRCEVSLLALYDNSTVGALASIIDHAKGGHLKTVRDEREVWLADTKLADDLPAPMTTPVNWQRDIEGRIFITGATGFVGAFLLSDLLHMPSVHQIGCLVRAPNSAAGMQRLRLALEKYNLWKDEFTNKLLAFPGLLEDKYLGLEQARFNELANWASVVFHLGARVNYTQPYSLHRPANTLGTINVVRFACTGRSKAVHYVSSISCFGPTGFFTGTASVGEDDSLLPHLEALPYDHGYAQSQWVADQLLRRLMDRGFPISIYRPGFITGHSQTGVCNPDDFFSRLMIACEQMKSYPMLPNQRKEFVPVDYVNSVILHIAASEHAVGRAYHIVPPNRDMSIDMDATMDLLGDAVNSRIHALPYMEWIDRLAANPPVALQPLQPMLAEKVHDANYPGGLKFPTLDCSLLKKYIAHLRSAC
What is the function of this protein?
Non-canonical nonribosomal peptide synthetase; part of the lnb gene cluster that mediates the biosynthesis of diastereomeric piperazines.  Lna and lnb clusters encode sets of enzymes that produce overlapping sets of previously undescribed metabolites such as piperazinomycin-like metabolites or morpholine (PubMed:23281040).  The lna and lnb biosynthetic pathways appear to be part of a signaling network that controls the formation of sclerotia, a resilient overwintering structure (PubMed:23281040).  One primary function of the non-canonical nonribosomal peptide synthetases lnaA and lnbA consists in the reduction of L-tyrosine (PubMed:23281040).  The presence in the clusters of tailoring enzymes such as the oxidoreductases lnaB, lnbB, lnaE or lnbE, as well as of the cytochrome P450 monooxygenases lnaC, lnaD, or lnbC, might explain formation of various diastereomeric piperazines (PubMed:23281040).
What are the official names of this protein?
Aldehyde reductase lnbA, Lnb diastereomeric piperazines biosynthesis cluster protein A, Non-canonical nonribosomal peptide synthetase lnbA.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: NRPA_SOYBN
Sequence: MDNNNDFWKFSDQLRLESGLANLSLNDYSIWSNSYSSKRPDQRRNFDVKGSDFNNNNNSSKAFDDDFNDGWKITNSNGPLFSMPHNNNNNTLEVGGFNKGGGIYSNTNTTISSYHPNNLNNNAFGGFNKGIYSNTTSSPYLNNNHHHLDDNNNLNRNNLKGYKTYFKGEDQFHTPKSAKKKNTTNNTNNKKHGDNTNNNDGTKTGAEKKFKTLPPSESLPKNETIGGYIFVCNNDTMAENLQRQLFGLPPRYRDSVRTITPGLPIFLYNYSTHQLHGIFEAASFGGSNIDPTAWEDKKCPGESRFPAQVQVITRKVCEPLEEDSFRPILHHYDGPKFRLELSVPEALSLLDIFANQNSFDDIFKAIPA
What is the function of this protein?
Involved in stress signaling pathway that mediates cell death in response to endoplasmic reticulum (ER) stress and osmotic stress.
What are the official names of this protein?
DCD domain-containing protein NRP-A, Asparagine-rich protein, N-rich protein, N-rich protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_STRPM
Sequence: MISRIKSFKNALNYDKMNCIEIILRRNDLMSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGFRKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGKEWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEAAQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVTFPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKELEAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEMYFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYNMPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EX7L_SALHS
Sequence: MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIAESMQPAGEGLLQQKYEQLKAKLHAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANARGECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQSAQQRLGMAMDYYLANRSRRFTQIFHRLQQQHPQLRLARQQTALERLRQRMGFALEARIKQANQRQQRVSQRLSQQNPQPRIHRAQSRIQQLEYRLTENIRSRLSEQRERFGNAVTHLEAVSPLATLARGYTVSTTTDGKVLKKIKQVKAGDIMTTRLEDGWLESEVKSVTPGT
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAAL_BACSU
Sequence: MGFLRKKTLRREFDEKLTEQLFKQKEEWNRQKKLVEKSLEPSAEVLYELKVAEAKYFFYLREAKQRNLKISRWK
What are the official names of this protein?
Uncharacterized protein YaaL.
Protein: RPIA_WIGBR
Sequence: MIEEKLKKQAAWAAIKYIKPGDIVGVGSGSTAEYFIDALGSIKNLIKGTVSSSRISSSKLKDLNIPLFDLNEVSLLNIYVDGADEINQKKHMIKGKGAALTREKIIASAAKKFICIVDSSKFVHVLGRAPLPIEVIPMARTLVSKKIIDIGGSPKYRKGIITENGNVLLDVHNLIILDSLFLEEKINNIPGVVSVGLFAHRAADIAIISGKNGIKIID
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RL3_FERNB
Sequence: MKFIIARKVGMTRLWKDEKVVPVTVLKAGPCVVVQKKTVEKDGYNAIQLGFEEVNEKKLTKPMLGVFKKANVKPMRVLKEFRVENVDQYSVGQEITVAIFQEGDKIDITGWTKGRGYSGAMKRWNFQGGPKAHGAKFHRELGSVGQHTEPARIFKGKRMPGRYGNERVTILNSEVVTIDAQNNLLAVKGGVPGARGSLVIIRSAVKQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RNH2_CHLP8
Sequence: MLSTEFETPLWENLSRVCGIDEAGRGPLAGPVVAAAVAFPRHFKPTGILEKLDDSKKLTAELREELAPAIRESAEAWAVAVVDAEIIDRINILQATMLAMNQAVESLAATPELLLVDGNRFRPVLPIPYQTIVKGDSKVFSIAAASVLAKTRRDELMVAYAAEYPAYGFDLHFGYPTARHVEAIARHGRCAIHRKSFKLRKLGEK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_SALEP
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVGQIKTRLGANPVPLQLAIGAEEGFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMQDLANEWHQNLIESAAEASEELMEKYLGGEELTEEEIKQALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKTARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPENPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYREAIRAKVTDIEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKSGPLAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDDAPNNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG176_MONPV
Sequence: MAFDISVNASKTINALVYFSTQQDKLVIRNEVNDIHYTVEFDRDKVVDTFISYNRHNDSIEIRGVLPEETNIGRVVNTPVSMTYLYNKYSFKPILAEYIRHRNTISGNIYSALMTLDDLVIKQYGDIDLLFNEKLKVDSDSGLFDFVNFVKDMICCDSRIVVALSSLVSKHWELTNKKYRCMALAEHIADSIPISELSRLRYNLCKYLRGHTDSIEDEFDHFEDDDLSTCSAVTDRETDV
What is the function of this protein?
BCL2-like protein which disrupts the host immune response by inhibiting the TLR4 signaling pathway leading to NF-kappa-B activation.  Acts close to the plasma membrane and targets several host TIR-domain containing adapter proteins including MYD88, TIRAP, TRIF and TICAM2.  In turn, blocks the host NF-kappa-B and TRIF-mediated IRF3 activation.
What are the official names of this protein?
Protein OPG176.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG176 family.
Protein: RL35_RHILW
Sequence: MPKMKTKSSAKKRFKITATGKVKAAAAGKRHGMIKRTNKFIRDARGTMVLAEPDGRKVIKNYLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RSMG_ECOLC
Sequence: MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVRDPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRVRFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGRFYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4726_BACC1
Sequence: MISQSTLFLFILLIIGLIAKNQSLTVAIGVLFLLKFTFLGDKVFPYLQTKGINLGVTVITIAVLVPIATGEIGFKQLGEAAKSYYAWIALASGVAVALLAKGGVQLLTTDPHITTALVFGTIIAVALFNGVAVGPLIGAGIAYAVMSIIQMFK
What are the official names of this protein?
UPF0756 membrane protein BCE_4726.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL2_XANC8
Sequence: MPLMKFKPTSPGRRSAVRVVTPDLHKGAPHAALLDSQSKSGGRNHHGRITVRHVGGGHKQHYRIIDFKRNKEGIPARVERIEYDPNRTAHIALLCYVDGERRYIIAPKGLKAGDQVIAGANAPIKTGNALPLRNIPVGTTVHGIELKPGKGAQIARAAGAAVQLVAREGIYATLRLRSGEMRKVPVECRATIGEVGNDEHNLEKLGKAGAKRRRGVRPTVRGAAMNANDHPHGGGEAKAGQGNPHPVTPWGVPTKGYKTRKNKRTQQFIVRDRRG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RGT1_ZYGRC
Sequence: MTPMSENNGSENTRDVSAAMMKSRSNSSEYAGGDGSFHASEVESQSSQGASGGNTSASKRRTKASRACDQCRKRKIRCDYDDDKGVCTSCRKNGESCAFERIQLKRGPSKGAVRGHSVSRSISGENNNTAATAVGSGGEFSSPSSRQGSVLLPPLGQYLPQPAPVPSNLNATQQQQFWKVPYHDFQGQRRGSIDSLSSDMSAKSVNIPQEHLLYASPSAGHPPLHSPVTFGPNNSSTDSGYWPFRNSGGEESDELRRKSGSNPPSLKNVSQPPPPPLQQQQQQQYSYSKFNNSFAQYGANGFPSRHGSIASEGMSPSASVPYQSVPMNQSNSNGLSQQQQQPIQWPKVQPKNLPPPQVQVQAADKEETLGNSFQKTIKKRRTVSASSGENKAEPGEYPLARFSSSGNDSLLGGNLVSPAGFVYGQIPEIQLIDIYYEFIHMVFPIIPLNKETVTNEILLVNTQPISPIHEINNYVILWFRNSLELLIRITLKRRSGHFYDSLTHSKERELSNEIRGNSNGGGSNDSKDDNLEMQGVFVTALNECLQKIVDIHPSFRENKDKISPKVKIIYLSTFVLLNYILAVVGYDNSFVLGMSTTIFKDFKVYELLLYDDEDDDATKSGSNDNDNTNNDNNSNNANNDNNDSRFYDENNAMNWDQAGYSITFKRLYVLLIIFDSLQCCSYGGPKLLNVPIEGASERFFQTKPHSNSKWVVDQSPTRMKFILQSVKFGELLAECSMKRRSICDLSRTQLTWEIPPYFLKGVTDEDDELFSLAQLLAAFILIRKEFVDCLLNLQDLETGELPTVDMELCGELIKLLCQLTSIILQALTVMMRTNPKNHIDYNYRPMKPMEHDDSGNSASRKFTTSQAESGKNSGNDFYHKLLGLQDNAEACLTNLLRGSISPYCISMLREIRNVMELVKKMPASLIGVVMACAGTHHNTANNNNNDPLAITFQSQELVVKLSNCMNDMMQITSLLNMIKPVNLSDQDSDNTSATATITTTETISKSLNRDHSIMRRLYYSKAAKRDKKHIYPSSSSSPQLQETITTLKSFVLIGWKLLDDFELGWS
What is the function of this protein?
Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose.  In the absence of glucose, it functions as a transcriptional repressor, whereas high concentrations of glucose cause it to function as a transcriptional activator.  In cells growing on low levels of glucose, has a neutral role, neither repressing nor activating transcription (By similarity).
What are the official names of this protein?
Glucose transport transcription regulator RGT1, Restores glucose transport protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDS1/RGT1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TIG_SHEFN
Sequence: MQVSVETTQGLERRLTISVPAEQIEKLVKDNVLREAKRARLPGFRPGKVPIGEINKRYGKAIRQDITGEVMQRNFIEAIVAEKLNPAGAPVFTPGSTEGDSFEFVATFEIYPEVVLTGLDSIAVEQPKAEVNDADVDVMIETLRKQHATFAPVERAAVADDKVKMNFIGSIDGEEFEGGKADDFELQLGSNRMIPGFETGIVGHKTGDEFEIEVTFPEDYHAENLKGKAAKFVITLTEVQAANLPEVNDEFASLFGIAEGGLDALKAEIRKNMTRELEQALKANVKEQVITGLLAANDIAIPKALVEGEVNVLRQQAMQRFGGQTENMPELPAELFTEQAERRVKIGLLLGEVIKTNELKAEDDRVNTLIESMASAYEDPSEVVSYYNSNKELMQNMRNVALEEQAVEALLKSSKVTVKDVAFEEFMNKATGRA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: NUON_SALAR
Sequence: MTITPQHLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNQEEFYLLVLIASLGGILLANANHLAALFLGIELISLPLFGLIGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGNLSFEALGKSLGDGMLREPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAVRVVLGIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPFRGPDADSLFSYRGLFWHRPVLAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQASLWWLVAAVVVGSAIGLYYYLRVAVSLYLHAPQQPGRDAPINWQYSAGGIVVLISALLVLVLGVWPQPLISLVQLATPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: U518_BRUMA
Sequence: MRRWFSKLGSTSLASTSRVTAFSSSESAAVEQLADSSIPPPITPFIIAKPDIHWNVDFASDPCSWESCFDAHWEAAEKLLENEEEISYEKVITVFQHLNCTVQLLMMEANAQPESAIGSILDRHFTHQIMERVVDWAIAAPHFLTPTCQVNMIGLYEVIVGESHTQNHCLLVHKPMLLPLLKLLDWCRKSAEKRNFTPSNTDRHFVLLLNQICTKLAEDTTLLHFFFDFDDDCDEQFLVFSLLIPYLYDSGEVGQLARDALLLILSVSRRLKRVATFIAVKSNFCPVVATGLSGCFSQLSRSFGSMLYVSDSWHKINADDIDSYSSLLDFHSSLIFCNAVIQVAHGYVVSQVIRYVYHGFLLPVVLPSLLQGGQDELISSTAYYHLCLDSVTETVLVQTIVKLLLNESCESNKTVLDVIVERISAGNRLSQVSLSLVRTLIDLRCEDIMFDLVFKYLLPCTFLQPNQTLHLKNQMYVRTAAQTLLTFVPECTYKSSALCSQETLHIYLSECRNYVQETTDACCEKWVWSYDGRSPFFMPKINSDEESATNSNGAFVRHSSVRSSMASARNGLNRYFVSRNAHITADSLRQHTPPPELGEQESSSRSSFPYDIADSSLVLDDEGDELIIPALTPTSLMMMTSSSDYFQFAYGELSETDTEAINPSVVSMSGAPAQSISDKASLASTSANCDTDIEMARSFVLRGWGQIEDTDTFMALMDRVPASKIKHSLEENMALIDSRIQYLEELKAEAKLQDLESDGFKSDTNNDNDDEDPAPLGKPIECFGNQGVGPFLESIMRSLENMLDNSLYVTLQTTSVLAALASYPQPLIAHYLFDQRMLLQPNVKNLFKVMDSLKTQIDAYASSLDGFDVLLERGIKFLRSRAERYEKVVESSRRLRSSESFSRNGNMEGRSSSRGLFNRFRSSNNKRLYPSNDSSHPHEFRIYTHKAIESRDVTLDHARAKQFVFAAIILSQFCQELAATVLQHSTVVPRPKVSPAKDYLRREVNSAGKDANCCAD
What are the official names of this protein?
FHIP family protein Bm1_18400.
What is the protein family that this protein belongs to?
Belongs to the FHIP family.