PharMolix/UniProtQA huggingface dataset:
Protein: TSP4_RAT
Sequence: MTMITPSSKLTLTKGNKSWSSTRCGAFLLLHLVLQPWQRAGAQATPQVFDLLPSSSQRLNPAALQPVLTDPTLHELYVISTFKLQSKSSATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKDDGKIHLVVFNNLQLADGRRHRILLRLSNLQRGAGSVELYLDCVQVDSVNNLPRAFSGLTQNPQAIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPIAPPAPPTRPTRRCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNGITCSDVDECKYHPCYPGVRCTNLAPGFRCDACPVGFTGPMVQGVGINFAKTNKQVCTDVDECRNGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCRTERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAGRAGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNVDQRNTDKDIFGDACDNCRGVLNNDQKDTDGDGKGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGMPDLFPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDKVIDRIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQIQTFDRLDN
What is the function of this protein?
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling.  Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling.  Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload.  May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury.  May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.
What are the official names of this protein?
Thrombospondin-4.
What is the protein family that this protein belongs to?
Belongs to the thrombospondin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Sarcoplasmic reticulum. Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: OLSB_RHOCB
Sequence: MAAAPLSYEIRLARDAQEIRASQRLRYAVFVEELGGAGPLIDHENRLEADEFDPLYDHLVLIDATKPEEDLDRVVAAYRLLRSDRAAEIGRFYCDAEYDLTPLRASGRRLLELGRSCVHPDHRGGAAMLMLWNALADYVLAHEIEILFGVASFHGTDVAALQQPLAWLHHHHLAPEGLRPRARQFQRMDLVAKEALDRRAALDAMPNLIKAYLRLGGFVGEGAFVDRPFNTTDVMLLMDTQAMSEKHREFYTRRVEGRG
What is the function of this protein?
Catalyzes the first step in the biosynthesis of ornithine lipids, which are phosphorus-free membrane lipids (Probable).  Catalyzes the 3-hydroxyacyl-acyl carrier protein-dependent acylation of ornithine to form lyso-ornithine lipid (LOL) (By similarity).
What are the official names of this protein?
L-ornithine N(alpha)-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. OlsB subfamily.
Protein: DAPK2_HUMAN
Sequence: MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKALHPRRRSSTS
What is the function of this protein?
Isoform 2 is not regulated by calmodulin.  It can phosphorylate MYL9.  It can induce membrane blebbing and autophagic cell death.
What are the official names of this protein?
Death-associated protein kinase 2, DAP kinase 2, DAP-kinase-related protein 1, DRP-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, autophagosome lumen.
Protein: PA2B1_BOTBZ
Sequence: SLWEFGQMILKETGKLPFPYYGAYGCYCGWGGRRGPKDATDRCCYVHDCKQICECDKAAAVCFRERKYMAYLRVLCKK
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that exhibits myotoxin and anticoagulant activity (PubMed:18602430).  Displays edema-inducing activities in mouse paw (PubMed:18602430).  Also displays cytotoxic activity against some cell lines and myotubes, and antimicrobial activities against E. coli, C. albicans and Leishmania (PubMed:18602430).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 myotoxin-I, MTX-I, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KCNE2_RAT
Sequence: MTTLANLTQTLEDAFKKVFITYMDSWRRNTTAEQQALQARVDAENFYYVILYLMVMIGMFAFIVVAILVSTVKSKRREHSQDPYHQYIVEDWQQKYRSQILHLEDSKATIHENLGATGFTVSP
What is the function of this protein?
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits.  Modulates the gating kinetics and enhances stability of the channel complex.  Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:19219384).  Associated with KCNH2/HERG is proposed to form the rapidly activating component of the delayed rectifying potassium current in heart (IKr).  May associate with KCNQ2 and/or KCNQ3 and modulate the native M-type current.  May associate with HCN1 and HCN2 and increase potassium current (By similarity).  Interacts with KCNQ1; forms a heterooligomer complex leading to currents with an apparently instantaneous activation, a rapid deactivation process and a linear current-voltage relationship and decreases the amplitude of the outward current (By similarity).  KCNQ1-KCNE2 channel associates with Na(+)-coupled myo-inositol symporter in the apical membrane of choroid plexus epithelium and regulates the myo-inositol gradient between blood and cerebrospinal fluid with an impact on neuron excitability.
What are the official names of this protein?
Potassium voltage-gated channel subfamily E member 2, MinK-related peptide 1, Minimum potassium ion channel-related peptide 1, Potassium channel subunit beta MiRP1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with KCNB1 at the plasma membrane.
Protein: NIT2_ASPNC
Sequence: MLSQVRVAVTQAEPVWLDLEATVKKTCDLIAEAAANGAQLVTFPECWIPGYPAWIWARPVDMRLSSIYIQNSLKIDSPQMASIQQCAAENKIVVVLGFSENLHNSLYISQAIIASDGKILTTRKKIKPTHMERTIFGDSFGDCLQSVVDTSAGRVGALSCWEHIQPLLKYHTYAQREQIHVAAWPPLFPHSEDGSLFSMSTEGTSSIARTYAIESQSFVLHTTTVIGQSGIDRMATSTGALMSTPGGGCSAIFGPDGRQLSQPIPSAEEGIIYADLDFEHIYHSKAFVDVCGHYSRPDLLWLGVEGGVKRHVRDNATTATPQVEQQEE
What is the function of this protein?
Nitrilase that hydrolyzes preferentially phenylacetonitrile, (R,S)-mandelonitrile, and 3-indolylacetonitrile.
What are the official names of this protein?
Arylacetonitrilase, NitAn2.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: ERPA_ACIAC
Sequence: MSAVAENIQTEMPAPIVFTDSAAAKVADLIAEEGNPDLKLRVFVQGGGCSGFQYGFTFDEITNEDDTTMTKNGVSLLIDAMSYQYLVGAEIDYKEDLQGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RS16_BACAN
Sequence: MAVKIRLKRMGAKKTPFYRVVVADSRSPRDGRFIEEIGTYNPVAQPAEVKINEEAALKWLGNGAKPSDTVRNLFSNQGIMEKFHLSKQGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ANM7_DROWI
Sequence: MSSFSQVRNPITGQATWQENADDYDYHQEVANAGFGDMLHDWERNQKYYAAIKKTIKRMQADGREVHVLDIGTGTGILSMMALKAGADSVTACEAFLPMANCAAKIMTANGADKIQLIRKRSTEIQIGVDMARRANLLVAELLDTELIGEGAIGIYNHAHQELLTKDALCIPARARCYAQVATSSLAKQWNGFKLMANLDGETLLRVPPQLNECKGDAALHDLQLSQLPTESFRLFSKPVEIFEFDFQQHLEPIQKQRNKVVPLQASQPGSADMVFYWWDIDLDHESEIVLSCAPFWAHPDKDKHVAGEDKPLANAIPWRDHWMQAIYYIPKPLHLSNTKETFYLSCHHDEYSLWFDAQLKEPAESIERHHCTCDLHLINPRSRIGQLNQSPRNKRYLNYLEETTTKDSQFLVLGNSCFLGLATCGLGAASVEIYDSNSLSRRLLDSFIKFNKLENVSLLEKLEDVQDHSKLTHIFAEPYFINSILPWDNFYFGTLLLSLKDKLSEGTQISPCAARIFALPMEFLDLHKIRAPVGNCEGFDLSLFDEMVKDSADKAVSSVEAQPLWEYPGRALAQPQEILRVDFANFNQELHQQGSIELIRSKECNGIALWVDWQLYSSESPKAFVTSGPSQPIEIGKFVKWDMFVRQGVHFPQTRTTNATQVEWQIDFKPFLGELNFKFDLKSI
What is the function of this protein?
Essential arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).  Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3 (By similarity).
What are the official names of this protein?
Protein arginine N-methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
Protein: PMIP_NEUCR
Sequence: MIQPLVKASRPRLWVCSDCLLRRTLSPLLRQQRRRFTGFTAHAPKTLTGTIPVTHKNGDTKHDDSLLRSIFDSPETWKQFSGDKHGRNVGLFRNAYLTSPHGFLDFAHVSLGKARALVDKVLNAQSLDEYRAIVRHLDRLSDILCRVLDMADFVRVTHPDQQIQRTASMAWDMMYEYMNQLNTMTGLYDQLVQAMDNPQVSTTWSEEERMVAEVLKLDFAKSAVHLPKDARDKFVHLSSAISQTGTNFIQHMEPKIPYTTVEKSRMMGMDPVEVKRMASMGKVYVQTLSPQASIALRTVRDDHARHQLFMASRTASRRTVHTLEELMLLRGESAKLSGFESYGHLVLHDRMMASTPESVRQFLQALSENTRPQAQQEVADLTAAKRAHKGGDATLEPWDKDFYAESIRQAIKSRQKREDLSSYFSLGTVMQGLSRIFTRLYGIRFVPREPMPGETWHPDVRRLDVVSDVEGHVAVLYCDLFYRPLKSPNPAHFTLRCSRELSPHEIAETAHTQAENPHVLIPSFESAEFAANDGMAYSRSQDGAIKQLPTIALVCDFPQQSHNRPALLSFFQLETLFHEMGHAIHSILARTSFQNVSGTRCATDLAELPSTLMEYFAADPSVLALFARHYETDNPLPYEWVDNKIREARRFEALDTENQIILAMLDQELHSSKAVQGHIDSTEIFHSLQRQFSTAPPDPQGTAWQGFFGHLVGYGSTYYSYLFDRVLAQRVWNVVFNSGQGGAALQRENGERLKENLLKWGGSKDPWKCLAGALKDERLEGGGEKAMKLVGSWGGQRGTKSDQAV
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase, MIP, Octapeptidyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NADK_SHESM
Sequence: MGINFDVSRPKARSSINMTTKFHTIGLIGKPHHPGTNQTLKRLHHWLTVQGYEVLVEERVASELGTHIVAVDLLEIGARCDLAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDLPPDAFEEALAKVLDGEFDTEHRFLLEAEVYRHGMLKASNTAVNEAVLHPGKIAHMIEFEVYIDNQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVDACSTIKMVVSPENGENLEVSCDGHVHLAVLPGDEIIVRRSSEQLRLIHPKGHNYFHVLRSKLGWGSKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIP1_CANGA
Sequence: MSSSEDEDDKFLYGSDNEEPKNEKKRPREAAEDDNEGPTSDKVVSQHNNDLKRPKLAKDSLANASSDEEESGSESDSDIEFIISTGPDPHRLDSSTVPGSNNAIVTVSEGANVGGETMSKSTATATTAEISTLNALGDTEVAGTSELDNETLGPETTTKSGTSAEGIDLDKEGLYNDEPVSTIDPEVLKEKPWRQPGANISDYFNYGFNEYTWMEYLHRQEKLRQEYNPRRILMGLMTLQQQGRLDQPQGGHQSMPDNMAINNPQPTNNDNMMHKPTPPLPNFPMPPMFGGFSPFMPPGMMAPMNRMPNQNQNQGQNQNQNQNQLSK
What is the function of this protein?
Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.
What are the official names of this protein?
Pre-mRNA polyadenylation factor FIP1.
What is the protein family that this protein belongs to?
Belongs to the FIP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBK_DAUCA
Sequence: MLNIFSLICICLNSAFYSSSLFFAKLPEAYAFLNPIVDLMPVIPLFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RUVC_HAEDU
Sequence: MPIILGIDPGSRITGYGIIRQQGRQLEYLGSGAIRINASDLPSRLKHIYAGVTEIITQFQPDMFAIEQVFMAKNADSALKLGQARGTAIVAAVNHDLPVFEYAARLVKQTVTGIGSADKLQVQDMVTRMLQLSAKPQVDAADALAIAITHAHSIQHSLIVAKQNNPSITTHKEQILALMKTRYSRGRFRLKG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MINC_BURCJ
Sequence: MSLKKSPFFELRSGSVDTLLFTVKTTDLDALRTELVKRFEATPEFFADDVVAIDVRRLADGERVALADIRQMLNDVRMRPVGVVALATQGWAGEAGLPLLEARDRRAPAAKPADEAEPAAVLAVEAAAAPAAAAAPEQSSDPVPTLLQAGGQTLVIDRPLRSGQQIYAKGDLVVLAPVSHGAEIIAEGNIHIYAPLRGRALAGVHGNHDARIFCTCLEPELISIAGIYRTTENPLPADVLGKSVQIRLEEEKLMIEPLRLT
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: SYN_BORAP
Sequence: MFASIKDILENPILNSNVTINGWIRTKRSNGKIGFIEINDGSTLKGIQAVINEEENQFDEKDLKNLTTGASISLTGLLVESPAKGQNYEIKTCGFNVIGEADPKTYPLQKKRHTFEFLREIPHLRIRTNTFGAVARVRSKISYKIHEYFQKNGFFYINTPIITSNDGEGAGEMFRVSTLKFNKPNNDLGNIDFKDDFFGKEAFLSVTGQLHGEAYAMALSKIYTFGPTFRAENSNTTRHASEFWMIEPEMAFYKLNDNITLAEDLLKYLLSSILNECSQDMDFLENYIEKGLIKKLENVINSNFEVITYTKAIEILESSKKNFEIKPYWGIDLQTEHERFLTEETFKKPVVVIDYPKNFKAFYMKINKDNKTVKGMDVLVPKIGEIIGGSEREDNLQKLENRIKELNLSIEHLNWYLDLRRFGSTPHSGFGLGLERFVQYSTGISNIRDSIPFPRTPKNLYF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_SYMTH
Sequence: MFVDVARIYVKGGDGGRGSNSVRREKYVPQGGPWGGDGGRGGDVVFVVDPGLNTLVDFKYQKHFKAERGEHGGPKGMHGRKGEDLVIKVPPGTVVKDDDTGEVLFDLVEPGQRAVVARGGRGGRGNMRFATPTNKCPTFYEKGEPGEERWLLLELKVVADVGLVGFPNAGKSTFLSAVSAARPKIANYPFTTLTPVLGVVDLGEGRSFVIADIPGLIEGAHQGVGLGHEFLRHVERTKVLIHVLDGAGTEGRDPLSDFDVIHNELRAYNPELAARPTLVAFNKMDLPDARENLPRVREALEKRGYRVFPISGATREGFRPLLEAAYDLIRQWVPPEPAAPEAEMVYRPKEEGWRIYKYGGVWHVEGKEIERLVAMTMWENDEAVARFLRILRLKGVEQALREAGAEDGDTVRVCDIEFELMADPV
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1470_STRPQ
Sequence: MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSVRHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS
What are the official names of this protein?
UPF0291 protein SPs0396.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSUN2_XENTR
Sequence: MGRRNRRNRQRHQRSTEQRSPAEEEQRRKAREQAAWECGYPEIIKENKLFEHYYQELKIVPDGEWDKFMASLREPLPATIRITGYKSHAKEILHCLKEKYFKELQDIEVDGQKIEAPQPLSWYPEELAWHTNLSRKIIRKSPELEKFHQFLVNETESGNISRQEAVSMIPPVLLKVQPHHKILDMCAAPGSKTAQIIEMLHADMNVPFPEGFVIANDVDNKRCYLLVHQAKRLNSPCIMVVNHDASSIPRLLVENNGSREVLYYDRILCDVPCSGDGTLRKNIDVWKKWTTLNSLQLHGLQIRIATRGVEQLAEGGRMVYSTCSLNPVEDEAVIASLLDKSEGSLELADVASEIPGLKWMPGITQWKVMTKEGHWYEKWEDIPTSRHTQIRPTMFPPKDEEKLKSMNLNRCMRILPHHQNTGGFFVAVLIKKAPMPWNKRQPKLQRRPPVSACDASIAVAPELVKAVTENSAGMADEPAVDTENGETKPCTNQSDSSKTDIVCCPPPSKKMKLFGFKEDPFVFVSEDDPIFDPIQTFYALDPSFPKKNLLTRTQEGKKRQLYMVSKELRNVLLHNSEKMKVINTGIKVLCRNNDGEQYGCAYRLAQEGIYTLYPFINARIVTVSIEDIKVLLTQENPFLSKFSKETQKQANNFDMGSIVLKYEPDPQEPETLQCPIVLCGWRGKTSIRSFVPKNERLHYLRMMGVEVFKEKAEVLEKKPVEGKACDEEHIDEKMDIDGAKEESKELSGNESGDDEDPKEEDVIDRGVLEHVALKNTSAIPASVEDQAEDASVSKESVD
What is the function of this protein?
RNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs).  Involved in various processes, such as epidermal stem cell differentiation, testis differentiation and maternal to zygotic transition during early development: acts by increasing protein synthesis; cytosine C(5)-methylation promoting tRNA stability and preventing mRNA decay.  Methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors.  tRNA methylation is required generation of RNA fragments derived from tRNAs (tRFs).  Also mediates C(5)-methylation of mitochondrial tRNAs.  Catalyzes cytosine C(5)-methylation of mRNAs, leading to stabilize them and prevent mRNA decay.  Cytosine C(5)-methylation of mRNAs also regulates mRNA export.  Also mediates cytosine C(5)-methylation of non-coding RNAs, such as vault RNAs (vtRNAs), promoting their processing into regulatory small RNAs.  Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
What are the official names of this protein?
RNA cytosine-C(5)-methyltransferase NSUN2, NOL1/NOP2/Sun domain family member 2, mRNA cytosine C(5)-methyltransferase, tRNA cytosine C(5)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. TRM4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Mitochondrion. Cytoplasm, cytoskeleton, spindle. Secreted, extracellular exosome.
Protein: RPOZ_BIFLS
Sequence: MAFGTDPTPDGLANPPIDDLMKHADSKYALAIFAAKRARQINSYFTQLNEGLLQNVGPLVEYQNNEKPLSIAFREIDEGLLEETLGEDDANEGN
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: GATA_BRAHW
Sequence: MELNELTIIQIREKLKNKEIDAPTLVDSIIKNIEEDNKRDDKIYAYLEIFKEEALEQAKKAQERINNGEDLPLLGVPLAIKDNLCYKDHLMTASSKMLEGYKAPYTAPTVQRLIDNGAIIIGRTNMDEFAMGGTTETSNYGVTRNPKNRAHVPGGSSGGSAAAVAANFAFGALGSDTGGSIRQPASFCGIVGVKPTYGRVPRLGCIAMASSLDQVGPLTKDVKDAALMTKIIAGFDPKESTTLNIPVPDYVAALDGNIKGMKIGLAKEYYDTDLIAADVKENVMDAIGKLKDQGAEIVDISLPNAKYGSRVYTAVMDVEVASNMGRYDGIRYGYHPKGDFNLDEYYYTSRSVGLAFETRARILFGTLMTGKRFFYSHYQHALKVRKLMQMDFDNAFKNVDVIVSPTSPVTAGLLGTRDQTDSALSFLADSYVSNINLVGLPAMSVPCGVDKNNMPIGIQFITKQFNEVDMFRMAYAHELANK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RL27_BURMS
Sequence: MAHKKAGGSSRNGRDSESKRLGVKVYGGQAINAGGIIVRQRGTRMHAGENVGMGKDHTLFALVDGHVKFTTKGAAKKHTVVVVPAAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y1243_PSYIN
Sequence: MNEEYSLQDLLGQESELQFAFFNNQTAWKLGCQLKKIAEDNSTLVAIEVYAFSQTLFSYAMSGTQLDNQIWIKRKRQTVLRFGHSSYYIGQYNKAKNREFEQQVHINADDYCAHGGAFPIRIKKCGLVGVVTVSGLPQREDHQMVIDALTDLIKSVQKS
What are the official names of this protein?
UPF0303 protein Ping_1243.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: TRMFO_MAGMM
Sequence: MAKITIIGAGLAGSEAAWQLAQRNIPVRLYEMRPHTMTPAHQTDHCGELVCSNSLRSDDHSNSAVGLLHQELRGLDSLIMRCADQHRVPAGGALAVDRHAFSAAITEALEQHPLIELIRQEIVTPPMEEDGYTIIASGPLTAGGLAHWIEAQVGKRMAFFDAIAPIVSHDSIDFSKAWKQSRYDKGDGNDYINCAMDEAQYHTFVQALLEGEKVAYKEFEANTPYFDGCLPIEVMAERGVETLRYGPMKPVGLTNPHKAEKSYAIVQLRQDNKLGTLWNMVGFQTKLSWPAQKRIFATIPGLEQAEFVRLGALHRNTFINSPTLLSETLQLKTQPRLLFAGQITGVEGYVESTACGLMAGRIVAHKMRGEAVSIPPQTTALGALMRHITGEADATHFQPMNVNFGLFPNFTERVPKKQRKEAYAQRALTHMQQWLQENS
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRN2_MEGVI
Sequence: YLDVNQIASYLLCLGQGAVFNGRKTCQIGCRAACQQPGCGGYKECEQIPNIRLHKYRCHCNSG
What is the function of this protein?
Has antimicrobial activity against Gram-positive bacteria and fungi.
What are the official names of this protein?
Megourin-2.
What are the subcellular locations of this protein?
Secreted.