PharMolix/UniProtQA huggingface dataset:
Protein: RAPA_SHEDO
Sequence: MPFALGQRWISDTESELGLGTVVQVEGRMVTLLFPATGENRMFSRAEAPLTRVIFNPNDTVESHEGWSITVTEVVEKDQLVVYHGTHSETGETVSLRETLISHNIRFNKPQDRLFAGQIDRLDRFGIRYQCQLLRHKLASSDLLGLQGPRVGLIAHQQWIAHEVGRRYAPRVLLADEVGLGKTIEAGLIMHQQLLTGRAERILVIVPDTLRHQWLVEMLRRFNLRFSVFDEDRCVEAYADNDNPFYTEQLVICSLELLRKKKRLDQALDADWDLLVVDEAHHLEWSEDAPSRAYQVVEALSEVVPGVLLLTATPDQLGHQSHFARLRLLDPDRFYDYDAFLTEEQGYQAVAEAAEALSGEKKLNDSAINSLTELLSEKDIAPSIRLIQANEVDPEQQQAARDGLLQELLDRHGTGRVLYRNSRASVKGFPKRIFNPHPQAMPEQYVTAERVNAMMSGKKTPQAKALEALSPEKLYQAFESDSASWWKFDTRVDWLIAFLKSHRSKKVLIIASQAETALSLEEALRTREGILATVFHEGMSIIERDKAGAYFAQEDAGAQALICSEIGSEGRNFQFASHLVLFDLPLNPDLLEQRIGRLDRIGQKNDIQIHLPYLEGTAQERLMQWYHHGLNAFELTCPSGHVLFNEFAEELTQVLCEDDADAMTQLLNHTQHKYKELKQAMERGRDKLLEINSHGGARAAALIERLAQKDNDTHLVGSVIRLWDIIGVDQEDNGENTIVLRPSEHMLFPTYPGLPEDGVTVTFDRETALSRDDIAFISEEHPLVQTGLDLITGSETGTTSVAVLKNKALPAGTLFLELIYMADASAPKSSQLYRYLPPTPIRVLLDKNGNNLATKVDYNNFEKQLSAVNRHIASKLVNASQPLLHPLLAKGQEQAQQGLDALLVDARASMTSQLTAELERLEALKAVNPNIREEELEYVRNQMAELNGYLDASQLQLDAIRMVLVSHV
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: GLGX_YERPA
Sequence: MAVLTHGSPTPSGAHFDGKGINFTLFSAHAEQVTLCLFDEQGQERQIAMPARTGDIWHGYLPGGKPGQRYGYRVSGPFEPSRGHRFNPHKLLIDPRTRALEGKVGDDPRFTGGVSQPDVRDSAAALPKCLVIHEEYDWQGDKPPAIPWGNTVIYEAHVRGLTQLHPDIPPELRGTYAALAHPALIEHLKTLGITTLELLPVQFHIDEPRLQKMGLSNYWGYNVLAPFAVDPDYASGREGISPLRELRDAVKALHNAGIEVILDVVFNHSAELDVFGPTLCQRGIDNASYYWLTPDGEYDNITGCGNALRLSHPYVTQWVIDCLNYWRDSCHVDGFRFDLGTVLGRTPAFDQHAPLFAALAADERLSACKLIAEPWDIGLGGYQLGNFPTGFSEWNDQYRDAMRGFWLRGEVPRGTFAQHFAASSRLFEQRGRLPSASINQITAHDGFTLLDLLCFNQKHNQMNGEENRDGSDNNHSNNFGCEGLVADAAIWQRRKACQRALLTTLLLSQGTPMLLAGDEQGHSQQGNNNAYCQNNILTWLDWGSADRALMTFTADLIRLRQQIPALTQDQWWQSGDSNVQWLDSQGQALSDAAWEQGCQQQLQILLSQRWLVLINATDHECEMHLPEGEWEGIPPFGVSDHAERLTTWRGSAHTICVLIKRD
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: HLDE_PHOPR
Sequence: MKLTLPDYDQASVLVVGDIMLDRYWYGPTGRISPEAPVPVVKVEQIEERPGGAANVAMNIAALGGHVHLVGLTGIDEPAKALNEKLTSLDVRCDFVSLPDYPTITKLRVMSRGQQMIRLDFEEGFHGVDKGLILPRLEQSLTHVKTVILSDYAKGALEHVSAMIKLARDAGKPVFIDPKGTDFERYRGATLLTPNLSEFELVAGKVTSDDELVEKGFELIERFDFEALLVTRSEHGMTLLQKGQAPLHLPTLAQEVYDVTGAGDTVISVLASSVAAGKSLADACKLANAAAGVVVAKLGTSTLSTIELTEAIYGSQDSGYGVIAETELKQAVSVARQRGETVVMTNGCFDILHAGHVAYLAEAAKLGDRLIVAVNSDSSVQGLKGPGRPVNPEDRRMAVLAGLGAVDWVVPFTEETPQRLISEILPSLLVKGGDYKPEDIAGGKEVIAAGGEVRVLSFEDGCSTSKIIEAIRGGKG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: NUOI1_ANADE
Sequence: MPYQLENRPPDLRESMYFPEIIRGIGTITKHFLKNLFFSRDANPDILARKRGGFGHSDNVTLQYPEERAPYAPAYRGLHRLVPREDGKPRCVACYMCATICPAQCIYIEAAEYPDDPVEKYPAKFVIDELRCIVCGFCVEACPKDAIRMDSGEHTPPSYERSAQIWDEKRLLRGPPVSYQYDPWLRRGSPSIPPDKLEEMRARAKPFPTVATDEASQTPGFSVRALAAEAKDRAQAARK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 1, NADH dehydrogenase I subunit I 1, NDH-1 subunit I 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CECR2_HUMAN
Sequence: MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSLSRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFPGEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
What is the function of this protein?
Regulatory subunit of the ATP-dependent CERF-1 and CERF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair (PubMed:15640247, PubMed:26365797, PubMed:28801535, PubMed:22464331).  The complexes do not have the ability to slide mononucleosomes to the center of a DNA template (PubMed:28801535).  The CERF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the CERF-5 ISWI chromatin remodeling complex (PubMed:28801535).  Plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development.  In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes (By similarity).  In histone-modifying complexes, CECR2 recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797, PubMed:22464331).  May also be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis (PubMed:11827465).
What are the official names of this protein?
Chromatin remodeling regulator CECR2, Cat eye syndrome critical region protein 2.
Protein: TRUA_CAMFF
Sequence: MMKIALTYSYNGSKFKGSQTQPDKNAVEDCLNFALNRVGIFKPVVSSSRTDKGVHAISQVSCVECGEFWNERFERLKNQINKHTKPYIYIKNIQKVSDEFHPRYDAVARSYRYIIYHDEQNVFLADYVHFYKTLNIQRLNIALKLFIGKHDFTPFYKVGSGEKSTVREIFYAKAYQIYKTKDAKFSAKFKTQKPTLTIINFKANGFLRAQVRLMVANALQACKSDENLYKFISNFKEQKPLTRMPSPPNGLYLKRVFY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PURR_HISS2
Sequence: MATIKDVAKMAGVSTTTVSHVINKTRFVAKETEQQVLQAIKNLNYSPSAVARSLKVNTTKSIGMIVTTCETPYFAEIIHSVEELCYRQGYSLFLCNTQNNPEKIKNHLDMLAKKRVDGLLVMCAEYTQNSLNLLAAFEDLPMVVMDWGPFNENTDLIQDNSFSGGYIATKYLIDNGHKDIAIISGELKKTTAVMRYQGFEKAMQEANLAINPDWIMEGFFEPEDGYECMNKILVQDKLPTAVFCCNDVMALGAISAIGEKSLKVPDDISVIGYDNIHASRFFSPPLTTIHQSKSRLGVQAINLLFKRISEKGKEHEIIEIYPELVIRKSVKTL
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: HYPA_ALBFT
Sequence: MHEMSLAEGVLQLIEDAARKDHFAKVTTVWLEIGQLSGVEPEAMVFCFDAVTRDSVAQGARLEIMTLPGTAWCMACAETVPMAEVFGQCPQCGGYQLQVTGGTEMRVKELEVE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: ALF_ECO57
Sequence: MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFTIAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVWLRAGQTSMIARLEKAFQELNAIDVL
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase class 2, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase, Fructose-bisphosphate aldolase class II.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: RISB_PHOPR
Sequence: MNVIEGAIAAPNAKIAIVIARFNSFINESLLAGALDALKRQGQVSDDNITVVRCPGAYELPLVAQQVAKSDRYDAIVALGSVIRGGTPHFDYVAGECNKGLAQVALEYNTPVAFGVLTVDSIEQAIERAGTKAGNKGAEAALSALEMVNVLSQIES
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MATRX_BRSVA
Sequence: METYVNKLHEGSIYTAAVQYNVIEKDDDPASLTIWVPMFQSSISADMLIKELINVNILVRQISTPKGPSLKIMINSRSAVLAQMPSKFTISANVSLDERSKLAYDITTPCEIKACSLTCLKVKNMLTTVKDLTMKTFNPTHEIIALCEFENIMTSKRVVIPTFLRSINVKAKDLDSLENIATTEFKNAITNAKIIPYAGLVLVITVTDNKGAFKYIKPQSQFIVDLGAYLEKESIYYVTTNWKHTATKFSIKPIED
What is the function of this protein?
Plays a crucial role in virus assembly into filaments and budding.  Early in infection, localizes in the nucleus where it may inhibit host cell transcription.  Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication.  During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer.
What are the official names of this protein?
Matrix protein, M protein.
What is the protein family that this protein belongs to?
Belongs to the pneumovirinae M protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=In the cytoplasm, associates with inclusion bodies. During bud formation, associates at the inner side of the plasma membrane of infected cells.
Protein: NMI_MOUSE
Sequence: MDADKDNIKQACDERSAEMDDMRGEQSMGLVHEIMSENKELDEEIKKLEAELQSDAREFQIKENVPEKKLKLTSVESPKDGCHFSNSSCSFQVSSQILYELQEGQALITFEKEEVAQNVISMGNHVVQMEGTPVKVSAHPVPLNTGVRFQVHVDISKMKINVTGIPDELSEEQTRDKLELSFCKSRNGGGEVESVDYDRKSRSAVITFVETGVVDKILKKKTYPLYMNQKCHSVAVSPCIERCLEKYQVFSAVSKKTVLLTGLEGIPVDEETGEDLLNIHFQRKNNGGGEVEVVKCSLDQSFAAYFKEEARETI
What is the function of this protein?
Acts as a signaling pathway regulator involved in innate immune system response (PubMed:23956435).  In response to interleukin 2/IL2 and interferon IFN-gamma/IFNG, interacts with signal transducer and activator of transcription/STAT which activate the transcription of downstream genes involved in a multitude of signals for development and homeostasis (By similarity).  Enhances the recruitment of CBP/p300 coactivators to STAT1 and STAT5, resulting in increased STAT1- and STAT5-dependent transcription (By similarity).  In response to interferon IFN-alpha, associates in a complex with transcriptional regulator IFI35 to regulate immune response; the complex formation prevents proteasome-mediated degradation of IFI35 (By similarity).  In complex with IFI35, negatively regulates nuclear factor NF-kappa-B signaling by inhibiting the nuclear translocation, activation and transcription of NF-kappa-B subunit p65/RELA, resulting in the inhibition of endothelial cell proliferation, migration and re-endothelialization of injured arteries (By similarity).  Negatively regulates virus-triggered type I interferon/IFN production by inducing proteosome-dependent degradation of IRF7, a transcriptional regulator of type I IFN, thereby interfering with cellular antiviral responses (PubMed:23956435).  Beside its role as an intracellular signaling pathway regulator, also functions extracellularly as damage-associated molecular patterns (DAMPs) to promote inflammation, when actively released by macrophage to the extracellular space during cell injury or pathogen invasion (By similarity).  Macrophage-secreted NMI activates NF-kappa-B signaling in adjacent macrophages through Toll-like receptor 4/TLR4 binding and activation, thereby inducing NF-kappa-B translocation from the cytoplasm into the nucleus which promotes the release of pro-inflammatory cytokines (By similarity).
What are the official names of this protein?
N-myc-interactor, Nmi, N-myc and STAT interactor.
What is the protein family that this protein belongs to?
Belongs to the NMI family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=Cytoplasmic NMI localizes in punctate granular structures. Nuclear localization increased following IFN-alpha treatment. Extracelullar following secretion by macrophage.
Protein: TRPD_SODGM
Sequence: MQAILEHLYQGGRISREQSQQLFGAIIQGQLAPEQLAAALISMKVRGEYSEEIAGAASALLADASPFPRPDYTFADIVGTGGDGSNSINISTASAIVAAGCGARVAKHGNRSVSSCSGSSDLLAAFGIRLDMPAALSRQALDELGICFLFAPQYHSGFSHAMPVRQLLKTCTLFNVLGPLINPARPPLALIGVYSPELVLPIAETLRVLGYQRAAVVHGGDMDEVALHAPTHVAELREGTIENYTLNAADFGLSAQPAEALRGGSPEENRDILARLLQGKGEHAHESAVAANVALLLKLFGQENLRDNTHRALEEIHSGAPYARVMALAARG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: USP_BOMMO
Sequence: MSSVAKKDKRTMSVTALINRAWPMTPSPQQQQQMVPSTQHSNFLHAMATPSTTPNVELDIQWLNIESGFMSPMSPPEMKPDTAMLDGFRDDSTPPPPFKNYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACREDKNCIIDKRQRNRCQYCRYQKCLACGMKREAVQEERQRAARRTEDAHPSSSVQELSIERLLELEALVADSAEELQILRVGPESGVPAKYRAPVSSLCQIGNKQIAALIVWARDIPHFGQLEIDDQILLIKGSWNELLLFAIAWRSMEFLNDERENVDSRNTAPPQLICLMPGMTLHRNSALQAGVGQIFDRVLSELSLKMRSLRMDQAECVALKAIILLNPDVKGLKNKQEVDVLREKMFLCLDEYCRRSRGGEEGRFAALLLRLPALRSISLKSFEHLYLFHLVAEGSVSSYIRDALCNHAPPIDTNIM
What are the official names of this protein?
Protein ultraspiracle homolog, BmCF1, Nuclear receptor subfamily 2 group B member 4, RXR type hormone receptor CF1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFG_CHRSD
Sequence: MARKTPLKRYRNIGIVAHVDAGKTTTTERVLFYTGLSHKVGEVHDGAATMDWMEQEQERGITITSAATTCFWQGMNKQFDEHRINIIDTPGHVDFTIEVERSLRVLDGAVVVLCGSSGVQPQTETVWRQANKYEVPRMVFVNKMDRAGADYFMVLDQLKQKLGANTVPIQINWGAEDDFKGVIDLIQMKGILWDEANHGMNYELVEIPDELKESAAKYREQMVEAAAEASEELMDKYLEEGDLSEADIKAGLRRRTLDNEIVLVTCGSAFKNKGVQAVLDGVIEYMPSPTEVKAIEGELDDKDGTIATREADDSAPFAALAFKIATDPFVGTLTFIRVYSGVLKSGDSIFNSVKSKKERVGRIVQMHSNSREEIKEVYAGDIAACIGLKDVTTGDTLCDLNDKIILERMEFPDPVISVAVEPKSKPDQEKMGTALGKLAQEDPSFRVKTDEETGQTIISGMGELHLDIIVDRLRREFKVDANIGKPQVAYRETIRASVEQEGKFVRQSGGRGQYGHVLLRIEPLTAEDKGEDEDMTFKFASEIVGGVVPKEYVPAVEKGAYEQLQNGVIAGYPMIDVKVTLFDGSYHDVDSNETAFKVASSMAIKEGAPKAKAVLLEPVMKVEVVTPEEFMGDVMGDLNRRRGLVQGMDDSPSGKIIRATVPLAEMFGYATDLRSQTQGRASYTMEFADYEEAPSSVVEAVINQNG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DINI_ECOLI
Sequence: MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRYAAANNLSVIGATKEDKQRISEILQETWESADDWFVSE
What is the function of this protein?
Involved in SOS regulation.  Inhibits RecA by preventing RecA to bind ssDNA.  Can displace ssDNA from RecA.
What are the official names of this protein?
DNA damage-inducible protein I.
What is the protein family that this protein belongs to?
Belongs to the DinI family.
Protein: RF1_PSE14
Sequence: MKASLLNKLDVLSDRFEELTALLGDAEVISDQTRFRAYSREYAEVEPVVALYQQLIRVQGDLEGAQALLKDSDPDMREMAVEEVRETKQQLVELEAQLQRMLLPKDPNDGRNVFLEIRAGTGGDEAAIFSGDLFRMYSRYAERRGWRVEILSENEGEHGGYKEVIARVEGDSVYGKLKFESGAHRVQRVPETESQGRIHTSACTVAVLPEPDEQQAIEINPADLRVDTYRSSGAGGQHVNKTDSAIRITHLPSGIVVECQEERSQHKNRARAMSWLSAKLNDQQTSAAANAIASERKLLVGSGDRSERIRTYNFPQGRVTDHRVNLTLYSLDEVLAGGVDAVIEPLLAEYQADQLAALGE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COP_STAEP
Sequence: MTFNKIFKYLISLLFLSILFHTIIHKNNLVFSKTMHKKVAFFSFSIFFVWIRHLKRYNSMLEKATFFVLQTSYTNELKGLYIAGNSYPYYQDKKKLVFNSFQKPFKNHQSTKIPRE
What is the function of this protein?
Putative control of replication message.
What are the official names of this protein?
Protein cop.
Protein: Y465_NEIMA
Sequence: MNTRPFYFGLIFIAIIAILANYLGNTDFSHHYHISALIIAILLGMAIGNTIYPQFSTQVEKGVLFAKGALLRTGIVLYGFRLTFGDIADVGLNAVVTDAIMLISTFFFTVLLGIRYLKMDKQLVYLTGAGCSICGAAAVMAAESVTKAESHKVSVAIAIVVIFGTLAIFTYPLFYTWSQDLINAHQFGIYVGSSVHEVAQVYAIGENIDPIVANTAVISKMIRVMMLAPFLLMLSWLLTRSDGVSENTSHKITIPWFAVLFIGVAIFNSFDLLPKELVKLFVEIDSFLLISSMAALGLTTHASAIKKAGLKPFVLGILTYLWLVVGGFLVNYGISKLI
What are the official names of this protein?
UPF0324 membrane protein NMA0465.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRHR_RAT
Sequence: MENETVSELNQTELPPQVAVALEYQVVTILLVVVICGLGIVGNIMVVLVVMRTKHMRTATNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVFYVMPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNKNMNLNTTNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELDDITVTDTYVSTTKVSFDDTCLASEKNGPSSCTYGYSLTAKQEKI
What is the function of this protein?
Receptor for thyrotropin-releasing hormone (TRH).  Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
What are the official names of this protein?
Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYNS_PSEP1
Sequence: MDKLEMHHLIMAAKARKGLSWDDLANAVGKAPVWLASVCYGMNSAPLEVATHLCEVLELDDQVAATLTAFPVKGWDKSIPQDPLIYRLYEVVGVYGPPLKDVIQEKFGDGIMSAIDFSMHVERIEDPKGDRVLLTLNGKFLPYRSW
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: SECA_LACAC
Sequence: MANILKKLYNTDKRELKKFEKYATKVEEHADEMSKLSDEQLQAKTPEFRERIKNGESLDDLLPEAFAVAREGAKRVLGLYPFHVQILGGIALHFGNIAEMMTGEGKTLTATMPVYLNALEGKGVHVVTVNEYLSSRDEEEMGQLYRWLGLTVGLNINSMSPDEKREAYNCDVTYSTNSELGFDYLRDNMVVYKEQMVQRPLNYAIIDEVDSILIDEARTPLIISGEAEQANSDYIRADRFVKTLTEDKSDDDADDDEDHGDYKIDWPTKTISLTRTGIEKACEHFGLKNLYDVENQKLVHHIDQALRANYIMLKDIDYVVQDGEVLIVDSFTGRVMEGRRYSDGLHQAIEAKEGVKIQEESRTQATITYQNFFRMYKKLSGMTGTGKTEEEEFREIYNMQVITIPTNRPIARKDMPDILYPTLDSKFHAVIEEIKKRHAKGQPVLVGTVAIESSERLSHLLDEANIPHAVLNAKNHAKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGYTRFYLSLEDDLMKRFGGDRVKDFLDRLSDNDDEKVIESRLITRQVESAQKRVEGNNYDTRKQTLQYDDVMRIQREIIYGERMQVIEADKSLKNVLIPMIHRTINSQVDMFTQGDRSQWRLDSLRDFISSSLASEQVTDSIDFKTISVEDLKKKLYDIVEKNFEDKEKALGDPSQMLEFEKVVILRVVDDRWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQDSGYRMFEEMISNIEFDVTRLFMKAEIRQNLSR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: AGALB_ASPOR
Sequence: MQRYISLSVSLSLLSGANALVRPDGVGRLPALGWNTWNAFGCDIDASKVLTAAEETINLGLKDAGYEYINIDDCWSVKSGRDPNTKRIIPDSAKFPDGISGVASKIHDLGLKVGIYSSAGTETCAGYPASLGYEKIDAESFAEWGIDYLKYDNCGVPTNWTDTYTHCVPDNSNGSKFPNGTCPDISNPAPTAYDWSSSNTAQRYNAMRDALLGVNRTILYSLCEWGQADVNTWGNGTGNSWRTTGDITPDWSRIVEIANENSFLMNYADFWGYPDPDMLEVGNGNLTLEENRAHFALWAAMKSPLIIGTALDSINEEHLAILKNKPLLSFHQDPVIGRPAYPYKWGYNPDWTFDPAHPAEYWSGPSSTLGGTLVLMFNSEDSAKHRTAVWSEIPELKDSAEKGSGYRVTEIWTGEDLGCVKDQYDVELQSHDIAALVVGESC
What is the function of this protein?
Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.
What are the official names of this protein?
Probable alpha-galactosidase B, Melibiase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Secreted.