PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_GLAP5
Sequence: MKILGIETSCDETGVAIYDEDKGLVANQLYSQIEMHADYGGVVPELASRDHIRKTLPLIQEALKEANLTASDIDGVAYTAGPGLVGALLVGSTIARSLAYAWNVPALGVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTQLVDVKNVGEYELLGESIDDAAGEAFDKTAKLLGLDYPGGAALAKLAESGTPNRFTFPRPMTDRPGLDFSFSGLKTFAANTINANLNEKGELEQQTRCDIAYAFQQAVIETLIIKCRRALQQTGYKRLVIAGGVSANKQLRHDLAELMKQIGGEVFYPRPQFCTDNGAMIAYAGFLRLKNGEQTDLSVSVKPRWPMVELCPIDV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_HALHL
Sequence: MDEHPPPPFPTVGIIGKPGDPAIAGLVERLLPMLEARGCTALLDEQSMPETGDDRHPQRVSRETLLDACDLIIAIGGDGTLIHIARAVAGRRDVALMGINRGRLGFLVDIAPEHLDEVAQILDGQHVVDERLLLHAEIRSNEDDTLLREDVAINEVVLHRWNTARMIELVTRIDGEPLSDHRSDGLILATPTGSTAYAMAGGGPIVHPNLHAMLLVPVCPHTLSNRPLVVDGSSRIEIDVHPRFIEHVRVSCDSQNDLTLQAGSRLVVRAHPSPVRLVHPPGYSYFNLLRAKLGWGGPLCNIEPFGA
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGLM_ASPNC
Sequence: MHSISALLSLLGGLALSSAAPTQNITSDAYFYGQSPAVYPSPEGTGTGSWASAYEKAKAFVAQLTDDEKVNLTAGVSSKTGCSGFIAEIPRLNFTGLCVSDASNGLRGTDYVNGWSSGIHVGASWNRTLARDRAKYMGQEFHRKGVNLLLGPVVGPLGRVAEGGRNWEGFSNDPYLTGALVYETVQGVQSSGVGVSTKHYIGNEQETNRNPETVNGVDVASVSSNIDDKTIHELYLWPFQDAVLAGSVAIMCSYERINNSYACQNSKTLNGLLKTELGFQGYVITDWGAQHGGIASANAGLDMVMPETTLWGSNLTTAIANGTMEASRLDDMATRIIATWYQLNQDTDFPTPGVGMPASAQSEHQVVVGTAPDEKSTLLESAIEGHVLVKNTNNALPLQTPQLVSVFGYDAKVTDSFDLASTVLGTSPLFQNYTLWVGGGSGSNSPAYVIAPLNAIQQQAYEDGTSVLWDVSAQDPEVDPTSEACLVFINSFATEGYDRSALTDDYSDTLVTNVASKCNNTIVVVHNAGIRLVYNWIDHENVTAVVLAHLPGQDTGHALVDILYGRANPSGKLPYTIAKQASDYGSLLHPSEPQTPYGLFPQSDFSEGVYIDYRAFDKDNITPQFEFGFGLSYTTFAYSGLSIEKTNETTSEYPPSAAIQEGGNPRLWDDLVTVTAEVQNSGSVDGAEVAQLYVGIPNGPVRQLRGFDKVLLSAGETAQVSFSLNRRDLSTWNVEAQQWQLQSGTYQVYVGRSSRDLPLTGEFSI
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase M, Beta-D-glucoside glucohydrolase M, Cellobiase M, Gentiobiase M.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYI_PYRFU
Sequence: MIKEPEFRDYTPGKLEEKIEQFWKESNIYQKVKELRKNGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIQKCKEFALNNLRIMTEQFKMLGVWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVRVDLNGREEYWILAKALVEKVLGDIGVKGEVVEEFKGKELEGLRYVHILMDEYPRQKEFREKYEWVHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPVDDQGKYVEGKWKGVYVKEADPQIIEHLKEKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKVSKVKEKIIKENDEKVTWYPEWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWKELVELAVAIEVNGERIDLPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKEMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASVIAFDTVPYRAVAMHGYVLDEKGDKMSKSLGNIIRPEEVVEKAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLSATYMSLDNFDPRNVKVEELEFREEDKWILSRVNNLIKEVENGIETFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGDDPDKLAAYYTLWKVFDVLLRLMAPFTPYITEEIYQNIMRPFTGIESVHMLDWPKPDESAVDEELEREMEFIRRIVEAGSAARQKAKIKLRYPVRKIIIETQDDTVKKAVERLNYILRDQLNAKEVVVGNVEREITVKPNFAKVGPEFKGDARLVAKWISEHGLELYEKGEVDVEIEGKKFHLTREHIIVEENIPDFLVAEDFEGGRVYVDKTLTRELLAEGLAREFVRRIQEMRKRLDLDVNDRIVVTIETTEENRELLQENLEYIMRETRAIEVRFEEAKGYVVEWPEVQAKIGIEKIE
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_PSET1
Sequence: MDSPFRTIGLIGKPNHPDAAATLQRLHTFLLALGFTVIVEKRTGSQLIDIPKNKLVKLVDLGEQADLAIVVGGDGNMLGAARVLARFDIAVIGVNRGNLGFLTDLNPEGFEASLEQVLSGEYVEEKRFLLEVEVYRHNELKSANSAVNEAVLHADKVAHMIEFEAFINNDFVFSQRSDGLIVSTPTGSTAYSLSGGGPILTPELNAIALVPMFPHTLSSRPLVVDADNEVRLKLSLENTDSLQVSCDSHVVLAVLPGDEVVIKKADKKLRLIHPKNYSYYNVLRQKLNWGSRLY
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_ENTH1
Sequence: MGRCLRNHSITYKTPKVPYERERFDAELKLVGQFGLKNKKEIQRVHYMLGHMRTIAKVMLMKDAKDPKRLLEGAALLRRLHNLGILPRDQNKLEFVLALKEENLLERRLQTLVYRKGFAKSIHHARVLIRGKMIKVGKQVVDVPSFLVRVESEPLIQLADNTPLTNPEINGRRKRKNNHAGKEDN
What are the official names of this protein?
40S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GPR19_MOUSE
Sequence: MVFAHRMDNDQPPVVTATLLVPLQNSSCAEAAEALLPHGLMGLHEEHSWMSNRTELQYELNPGEVATASIFFGALWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVVLQFTTGRWTLGSAMCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWILDAAFVTPVFFFYGSNWDSHCNYFLPPSWEGTAYTVIHFLVGFVIPSILIILFYQKVIKYIWRIGTDGRTLRRTMNIVPRTKVKTVKMFLLLNLVFLFSWLPFHVAQLWHPHEQDYKKSSLVFTAVTWVSFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTITTSSRMAKRNYVGISEIPPVSRTITKDSIYDSFDREAREKKLAWPINSNPPNTFV
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 19.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CX3C1_RAT
Sequence: MPTSFPELDLENFEYDDSAEACYLGDIVAFGTIFLSIFYSLVFTFGLVGNLLVVLALTNSRKSKSITDIYLLNLALSDLLFVATLPFWTHYLISHEGLHNAMCKLTTAFFFIGFFGGIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWAAAILVASPQFMFTKRKDNECLGDYPEVLQEIWPVLRNSEVNILGFVLPLLIMSFCYFRIVRTLFSCKNRKKARAIRLILLVVVVFFLFWTPYNIVIFLETLKFYNFFPSCGMKRDLRWALSVTETVAFSHCCLNPFIYAFAGEKFRRYLRHLYNKCLAVLCGRPVHAGFSTESQRSRQDSILSSLTHYTSEGEGSLLL
What is the function of this protein?
Receptor for the C-X3-C chemokine fractalkine (CX3CL1) present on many early leukocyte cells; CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis.  CX3CR1-CX3CL1 signaling mediates cell migratory functions.  Responsible for the recruitment of natural killer (NK) cells to inflamed tissues.  Acts as a regulator of inflammation process leading to atherogenesis by mediating macrophage and monocyte recruitment to inflamed atherosclerotic plaques, promoting cell survival.  Involved in airway inflammation by promoting interleukin 2-producing T helper (Th2) cell survival in inflamed lung.  Involved in the migration of circulating monocytes to non-inflamed tissues, where they differentiate into macrophages and dendritic cells.  Acts as a negative regulator of angiogenesis, probably by promoting macrophage chemotaxis.  Plays a key role in brain microglia by regulating inflammatory response in the central nervous system (CNS) and regulating synapse maturation.  Required to restrain the microglial inflammatory response in the CNS and the resulting parenchymal damage in response to pathological stimuli.  Involved in brain development by participating in synaptic pruning, a natural process during which brain microglia eliminates extra synapses during postnatal development.  Synaptic pruning by microglia is required to promote the maturation of circuit connectivity during brain development.  Acts as an important regulator of the gut microbiota by controlling immunity to intestinal bacteria and fungi.  Expressed in lamina propria dendritic cells in the small intestine, which form transepithelial dendrites capable of taking up bacteria in order to provide defense against pathogenic bacteria.  Required to initiate innate and adaptive immune responses against dissemination of commensal fungi (mycobiota) component of the gut: expressed in mononuclear phagocytes (MNPs) and acts by promoting induction of antifungal IgG antibodies response to confer protection against disseminated C. albicans or C. auris infection (By similarity).  Also acts as a receptor for C-C motif chemokine CCL26, inducing cell chemotaxis (By similarity).
What are the official names of this protein?
CX3C chemokine receptor 1, C-X3-C CKR-1, CX3CR1, Fractalkine receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IXOL_IXOSC
Sequence: MNAAFIAALLILGALTLDAMAYSFTCERIPCTNNSDCHGSDLCQCRPPRGDGFSYFCSEY
What is the function of this protein?
Tick salivary platelet aggregation inhibitor that plays an important part in the anti-hemostatic strategy of ticks.  Inhibits platelet aggregation induced by ADP, thrombin and thromboxane A2 (TXA2).  Blocks platelet adhesion to soluble collagen (most probably through the binding to alpha-2/beta-1 integrin (ITGA2/ITGB1)) and binds to purified glycoprotein IIb/IIIa (ITGA2B/ITGB3) in a dose-dependent manner.  In vivo, reduces thrombus weight effectively in a rat arteriovenous shunt model and inhibits thrombosis in a carrageenan-induced mouse tail thrombosis model.
What are the official names of this protein?
Ixodegrin-like peptide, Platelet aggregation inhibitor, PAI, Tick anti-thrombosis peptide.
What is the protein family that this protein belongs to?
Belongs to the ixodegrin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CMOB_SHEHH
Sequence: MISFSSFYKQISDSSLQHWLETLPSILGQWQREHKHGSLPKWEKVLNKLHYPEADIIDFKTSVKIGSGDQLSDGERQKLENLLAIFKPWRKGPYSLHGIEIDTEWRSDWKWERVVPHISPLENRTVLDVGCGSGYHMWRMLGEGAKHVVGIDPSPLFMCQFEAVKRLAGNEQPIHFLPLGIEELPALDAFDTVFSMGVLYHRRSPIDHIFQLRDQLRVGGELVLETLVIDGDENTVLMPTDRYGKMNNVWFLPSVEMLMLWLKKCDFTDIRCVDVDVTSLAEQRSTPWMPNESLVDYLDPNDVSLTVEGYPAPKRATIIATKNQPNKDLI
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: HIS3_ACICJ
Sequence: MTHPVITAARFNEAGLIPAIAQQHDTGEVLMMAWMNAESIAESLSTGQVCYFSRSRGKLWRKGESSGHVQRLVEMRLDCDGDTLLLLVEQTGPACHTGAHNCFFRRVTKDGLEEIA
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_LACCB
Sequence: MIVIVDYDTGNTRNVKKALDYLGVNNQLSADPAIIMAASGLILPGVGAFKEAMKALNQRQLVPVIQAFAATGKPLLGICLGMQLLFDRSFEFGETAGLGLIPGEVVAIPTDSGLAVPHMGWNTNSLTQPDLFAAVFADQATYFVHSFYATTLPQFTLATTDYGQPLTSIVRRNNVLGTQFHPEKSGAIGLAGLKKFKEMTEDEALSRD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB2I_CARML
Sequence: MDIKSQTLYLNLSEAYKDPEVKANEFLSKLVVQCAGKLTASNSENSYIEVISLLSRGISSYYLSHKRIIPSSMLTIYTQIQKDIKNGNIDTEKLRKYEIAKGLMSVPYIYF
What is the function of this protein?
Could impart immunity to carnobacteriocin-B2 to naturally sensitive host strains.
What are the official names of this protein?
Putative carnobacteriocin-B2 immunity protein, Carnocin-CP52 immunity protein.
Protein: RHO_TREPA
Sequence: MKVSVGTVVGQGELGLEEGIVGNQIVSEDSAADVGECDAYGGRKKLVIRSRSRRRVVTPKALEVEKRPRRALRFKQNFCPEDAETSESSADVKGRARLLIDDLTEMGMHALRDFAVQRGISQEDVVVMKKSDIIFHVLKNHTENGGVIFASGSLEILPDGYGFLRSPQNSYLPGSDDIYVSPSQIRLFNLKTGDTIYGQIRSPKEGERFFAMLRVETVNFEEVAKVQDRVPFDSLTPLYPREKLNLETRTEDISTRVMNLFCPIGKGQRALIVAPPRTGKTILMQKIANAITQNHPEVYLIVLLIDERPEEVTDMERTVDAEVISSTFDEQATRHVQIAEIVLERAKRLVEHRKDVVILLDSITRLARAYNQTMPTSGKVLSGGVDSNALHKPKRFFGAARNVEEGGSLTIIATALIETGSRMDEVIFEEFKGTGNMEINLDRRLSDRRLFPAVSIKKSGTRKEELLLTEEEMQRIWVLRKVINPMDDAEIVELLIDKMRKTKNNEAFLRSMNTGAFSS
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: MNTP_KLEP3
Sequence: MNLSATILLAFGMSMDAFAASIGKGATLHKPKFSEAVRTGLIFGVIETLTPLVGWGLGMLASQFVLEWNHWIAFILLVFLGGRMIVEGVRGDSDEACDAPRRHGFWLLVTTAFATSLDAMAVGVGLAFLQVSIVTTALAIGCATFLMSTLGIMVGRFIGPLLGKRAEILGGIVLIGIGSEILWSHFAG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y112_OSHVF
Sequence: MVDKIQSRWPTLMNQVSFDERYVNYKDRDADTVLARRLSACNLGFVYTKNFSAKTKRMLTSATRSICATSTGNNIDFGIFAAMLRNCDKVGVNSKSLTNLQPVGGAIFEEMFNFSQRNDFFIRPTIPFVGKVRAITQSLTPSMVIMPRVNDDRFGPSGIATFNAVLSGIMPVNEPERGLYLPTDLTYNIERITRSVMHKYTDETTNMPVFMAIGPYNEMLCGNNLGNKYLPRNTAFNASSVLQGRKVGDKIAYDQKLCCCFWIGTHNETEYSVLTELQKICIRNGRASVIPDEMKEIAVIKIGVVPSNKSACASFDSKTLRIENFVFQPDHTWELTQYTDRRVFSAANVDTSDFKDVEGDVNSIFDYGYMEMAGTEDKILEEEEEETMDETPEDILRTSNLQFAQPIGNNKSSPMKREFTAMEEDKTETGDIFKLLSQQKPAKGAKSKSKKYKKTEEDLSAV
What are the official names of this protein?
Uncharacterized protein ORF112.
Protein: LSPA_XANC8
Sequence: MSQRPNPSALIWLLLSAVVIGLDQWSKAWVLSSLPEYTPVPVIDGFWNWYRTYNTGAAFSFLSDAGGWQLWFFTALAVGISGLLAFWLSRTARGDWRSAVPYALVIGGAIGNVIDRLMHGHVVDFIQWYVGEHTWPSFNIADSAIVGGAIGIALFGLFDGKRSRKAG
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TDH_SYMTH
Sequence: MAETMRALRKLEAGPGATLQEVPIPTIGPRDVLVKVRAASICGTDYHIYTWDPWSAGRVKPPLTIGHELAGEVVAVGREVTACKVGDYVSAETHIVCNRCPRCHMGEYHLCENTKILGVDTDGAFAEYVAVPEQNIWVNDKDIPFELQSIQEPLGNAVHTALNGDLTARSVLITGCGPIGIMSVPVAKMAGAEIVMAMDINEYRLQLAGQLGADVLINPTKQDPVEVVRSYTRGYGADVVLEMSGNPTAIRQGLKAARNGARISLLGLPGRPLELDLAADVIMRGLVLQGITGRRMWQTWYQVRSLYRAGLAERLRPLVTHRMPLEQIDAAMELMGSGQSGKIVLVPDLKA
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_LEGPA
Sequence: MARIAGVNIPDHKHVVIALTAIYGIGKTTSLKLCKTVDIDPSVKVSQLSDAQLESLRTEIAKITVEGDLRRVVTMNIKRLMDLGCYRGLRHRRGLPLRGQRTKTNARTRKGRRKGTSS
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NAGZ_VIBC3
Sequence: MGPLWLDVAGYELSAEDREILQHPTVGGVILFGRNYHDNQQLLALNKAIRQAAKRPILIGVDQEGGRVQRFREGFSRIPPAQYYARAENGVELAEQGGWLMAAELIAHDVDLSFAPVLDMGFACKAIGNRAFGEDVQTVLKHSSAFLRGMKAVGMATTGKHFPGHGAVIADSHLETPYDERETIAQDMAIFRAQIEAGVLDAMMPAHVVYPHYDAQPASGSSYWLKQVLREELGFKGIVFSDDLSMEGAAVMGGPVERSHQALVAGCDMILMCNKREAAVEVLDNLPIMVVPQATALLKKQQFSYSELKRLDRWQQASANMQRLIEQFSV
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHSP1_HUMAN
Sequence: MSSEPPPPPQPPTHQASVGLLDTPRSRERSPSPLRGNVVPSPLPTRRTRTFSATVRASQGPVYKGVCKCFCRSKGHGFITPADGGPDIFLHISDVEGEYVPVEGDEVTYKMCSIPPKNEKLQAVEVVITHLAPGTKHETWSGHVISS
What is the function of this protein?
Binds mRNA and regulates the stability of target mRNA.  Binds single-stranded DNA (in vitro).
What are the official names of this protein?
Calcium-regulated heat-stable protein 1, Calcium-regulated heat-stable protein of 24 kDa, CRHSP-24.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule. Note=Detected at cytoplasmic stress granules and P-bodies. Detected at exosome granules where mRNA is degraded (By similarity).
Protein: VME1_MERS1
Sequence: MSNMTQLTEAQIIAIIKDWNFAWSLIFLLITIVLQYGYPSRSMTVYVFKMFVLWLLWPSSMALSIFSAVYPIDLASQIISGIVAAVSAMMWISYFVQSIRLFMRTGSWWSFNPETNCLLNVPFGGTTVVRPLVEDSTSVTAVVTNGHLKMAGMHFGACDYDRLPNEVTVAKPNVLIALKMVKRQSYGTNSGVAIYHRYKAGNYRSPPITADIELALLRA
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: SPD2B_MOUSE
Sequence: MPPRRSIVEVKVLDVQKRRVPNKHYVYIIRVTWSSGATEAIYRRYSKFFDLQMQMLDKFPMEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPEDLNPPKEEHIGKKKSGNDPTSVDPMVLEQYVVVADYQKQESSEISLSVGQVVDIIEKNESGWWFVSTAEEQGWVPATCLEGQDGVQDEFSLQPEEEEKYTVIYPYTARDQDEMNLERGAVVEVVQKNLEGWWKIRYQGKEGWAPASYLKKNSGEPLPPKLGPSSPAHSGALDLDGVSRHQNAMGREKELLNNQRDGRFEGRLVPDGDVKQRSPKMRQRPPPRRDMTIPRGLNLPKPPIPPQVEEEYYTIAEFQTTIPDGISFQAGLKVEVIEKSLSGWWYIQMEDKEGWAPATFIDKYKKTSSASRPNFLAPLPHEMTQLRLGDAAATENNTGPEAVGPSRPLPEAPHGAVDSGMLWSKDWKGGKEAPRKASSDLSASTGYEEISDPTQEEKPSLPPRKESIIKSEEELLERERQKMEPLRGSSPKPPGMILPMIPAKHAPLARDSRKPEPKLDKSKFPLRNDMGLECGHKVLAKEVKKPNLRPISRSKAELSEEKVDPTSQNLFMKSRPQVRPKPTPSPKTEPAQSEDHVDIYNLRSKLRPAKSQEKALLDGESHHAAGSHDTALSRSFLPGEGPGHGQDRSGRQDGLSPKETPCRAPPRPAKTTDPGPKNVPVPVQEATLQQRPVVPPRRPPPPKKTSSSPLSCRPLPEVRGAQREESRVAPAAGRALLVPPKAKPFLSNSSVGQDDMRGKGGLGPRVTGKVGETREKAASFLNADGPKDSLYVAVANFEGDEDTSSFQEGTVFEVREKNSSGWWFCQVLSGAPSWEGWIPSNYLRKKP
What is the function of this protein?
Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation.  Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides.  Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization.  Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.
What are the official names of this protein?
SH3 and PX domain-containing protein 2B, Factor for adipocyte differentiation 49, Tyrosine kinase substrate with four SH3 domains.
What is the protein family that this protein belongs to?
Belongs to the SH3PXD2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, podosome. Note=Cytoplasmic in normal cells and localizes to podosomes in SRC- transformed cells.
Protein: MNMG_PROMP
Sequence: MKDPQSPNESFDIIVIGGGHAGCEAAITTAKLGFSTALFTINLDRIAWQPCNPAVGGPAKSQLVHEIDALGGIIGQLADETAIQKRILNASRGPAVWALRAQTDKREYSKRMIEILQNTDNLSLKEAMITELVIKEAETFSNNLKNKTKKIKGVKTFFGTYYYAKSIIITAGTFLEGRIWIGNKSMSAGRSGEQAAQGLTQSLHNLGIKTERLKTGTPARVDKKSISFDELDIQPSTASDKYFSFDPKIKNNMPQVSCHITRTTLKTHELIRNNLHLTPIYGGFIDSKGPRYCPSIEDKIVKFADKNSHQIFLEPEGINTPEIYVQGFSTGLPENIQLDLLRTLPGLNKCKMLRPAYAVEYEYIPATQLKSSLETIEIENLFSAGQINGTTGYEEAAAQGLVAGINATRKLNMKDPIIFSRESSYIGTMINDLITRDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGFEIGLIDERRWLAHKKKMKSLKEENSRLENTRLKCTDEIAKKIELDSGSKIKGSTTLKELLKRPNLHYSDFIRYDLVDKTLPISVIEGVEIDIKYEGYLKRQKNNIDQINRQSLKSLSSEINYDQIDTLSLEARENLNKIKPTNFGDASKIPGVSKADLTALLVWLKIKELKNEKKTSFAEKKLSS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARSB_STAAU
Sequence: MTILAIVIFLLTLTFVIWQPKGLDIGITALIGAVVAIITGVVSLSDVLEVTGIVWNATLTFVAVILISLILDEIGFFEWSAIHMVKASNGNGLKMFVFIMLLGAIVAAFFANDGAALILTPIVLAMVRNLGFNQKVIFPFIIASGFIADTTSLPLIVSNLVNIVSADYFDIGFIEYFSRMIIPNIFSLIASILVLWLYFRKSIPKTFDTENLSDPKSAIKDSKLFKLSWIVLAVLLVGYLVSEFIQIPVSIIAGIIAFIFVILARKSKAVHTKQVIKGAPWNIVVFSIGMYLVVFGLKNVGITTILGDVLTNISNYGLFSSIMGMGFIAAFLSSIMNNMPTVLIDAIAIGQSSATGILKEGMVYANVIGSDLGPKITPIGSLATLLWLHVLTQKGVKISWGTYFKTGIIITIPVLFVTLLGLYLTLIIF
What is the function of this protein?
Involved in arsenical resistance.  Thought to form the channel of an arsenite pump.
What are the official names of this protein?
Arsenical pump membrane protein, Arsenic efflux pump protein.
What is the protein family that this protein belongs to?
Belongs to the ArsB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.