PharMolix/UniProtQA huggingface dataset:
Protein: KPHAB_ACTTE
Sequence: RCKTCSKGRCRPKPNCG
What is the function of this protein?
Voltage-gated potassium channel inhibitor that is certainly used for prey capture (PubMed:30109357).  It inhibits several potassium channels, but not all (Kv1. 1/KCNA1 (IC(50)=353 nM), Kv1. 2/KCNA2 (IC(50)=146 nM), Kv1. 3/KCNA3 (IC(50)=3051 nM), Kv1. 6/KCNA6 (IC(50)=191 nM), and Shaker IR (23% inhibition at 3 uM)) (PubMed:30109357).  In vivo, injection of this toxin into amphipods results in impaired swimming followed by contractile paralysis (PubMed:30109357).
What are the official names of this protein?
Kappa-actitoxin-Ate1a, Ate1a.
What is the protein family that this protein belongs to?
Belongs to the sea anemonne PHAB family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: FRDA_MYCBO
Sequence: MTAQHNIVVIGGGGAGLRAAIAIAETNPHLDVAIVSKVYPMRSHTVSAEGGAAAVTGDDDSLDEHAHDTVSGGDWLCDQDAVEAFVAEAPKELVQLEHWGCPWSRKPDGRVAVRPFGGMKKLRTWFAADKTGFHLLHTLFQRLLTYSDVMRYDEWFATTLLVDDGRVCGLVAIELATGRIETILADAVILCTGGCGRVFPFTTNANIKTGDGMALAFRAGAPLKDMEFVQYHPTGLPFTGILITEAARAEGGWLLNKDGYRYLQDYDLGKPTPEPRLRSMELGPRDRLSQAFVHEHNKGRTVDTPYGPVVYLDLRHLGADLIDAKLPFVRELCRDYQHIDPVVELVPVRPVVHYMMGGVHTDINGATTLPGLYAAGETACVSINGANRLGSNSLPELLVFGARAGRAAADYAARHQKSDRGPSSAVRAQARTEALRLERELSRHGQGGERIADIRADMQATLESAAGIYRDGPTLTKAVEEIRVLQERFATAGIDDHSRTFNTELTALLELSGMLDVALAIVESGLRREESRGAHQRTDFPNRDDEHFLAHTLVHRESDGTLRVGYLPVTITRWPPGERVYGR
What are the official names of this protein?
Fumarate reductase flavoprotein subunit, Quinol-fumarate reductase flavoprotein subunit, QFR flavoprotein subunit.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MEND_YERPP
Sequence: MSTSVFNRRWAALLLEALTRHGVRHICIAPGSRSTPLTLAAAANPSLVCHTHFDERGLGHLALGLAKASTEPVAVIVTSGTAVANLYPALIEAGLTGERLILLTADRPPELIDCGANQAIRQQGLFASHPTLSVNLPRPTPDISARWLVSTLDSAMAQLQHGALHINCPFAEPLYGGDEQQYADWSASLGDWWQDCHPWLRQTCYPPSLYQPPAQQADWFFWRQKRGVVIAGRMGAQEGRQLTAWAAMLGWPLIGDVLSQTGQPLPCADLWLAHPRAQETLAQAQMVLQFGSSLTSKRLLQWQTACQPQEYWLVDSAPGRLDPANHRGRRIICPVGEWLSRHPAQRRTPWATELAAYSESAQAQVIETLAGQFSEAAVAHQLAELLPDNGQLFVGNSLIVRLIDALGQLPAGYPVYSNRGASGIDGLLSTAAGVQRATAKPTLAIVGDLSALYDLNALALLRQSSAPMVLLVINNNGGQIFSLLPTPEAERQRFYCMPQDVNFEHAAVMFSLGYARPNSWPQLRELVHQCWLRGGTTLIEVQVPPSQGAETLQQLVQQVTLIPQVAP
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: SI173_DICDI
Sequence: MTLLSSISKIGTIKNGNSLNEITSTISNNEAKGSPSFSGNQSTKSIGDLLLQIAIITKATTKNK
What are the official names of this protein?
Protein sigN173, SrfA-induced gene N-like protein 173.
Protein: GMHBB_PHOLL
Sequence: MTQGIPAVFLDRDGTINIDHGYVHEIDDFQFIDGVIEAMIELKKMGYALVLVTNQSGIARGIFDEEQFLQLTEWMDWSLADRGVDLDGIYYCPHHPDATEEQYKKSCDCRKPQPGMLLDAQRELSIDMTASFMIGDKLEDMQAATLAKIGTKVLVRTGKPVNTEAEQAANLIINSLADLPKAIKGIKK
What is the function of this protein?
Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
What are the official names of this protein?
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the GmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_CAMFF
Sequence: MKNIVFMGTPDYASVILEAILKNGGYNVVAVFTQPDRPVGRKAILTPPEVKKTVLQSGLDIPIFQPLNLKDSSTVNDIKALKPNFIVVAAYGQILPKDILDIAPCINLHASLLPKFRGASPIQEAILRGELLSGVTAMRMGVGLDDGDILGFSVIEIPNLKSSQLFCELAKMAAKLTIKILNEFESISPIAQFHALSSKCGKVHKEDGLIDIKLQTPKIIESKFRAYYPWPGLYLENGVKIWDMEISNLKGENGYVLSIDYDGFTIGVNGGSIKIKSLQESGKKMVNAKDYINGKRLGVGSKFC
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: TYRDC_ENTFA
Sequence: MKNEKLAKGEMNLNALFIGDKAENGQLYKDLLIDLVDEHLGWRQNYMPQDMPVISSQERTSESYEKTVNHMKDVLNEISSRMRTHSVPWHTAGRYWGHMNSETLMPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGHEFAHLMSYKNGWGHIVADGSLANLEGLWYARNIKSLPFAMKEVKPELVAGKSDWELLNMPTKEIMDLLESAEDEIDEIKAHSARSGKHLQAIGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIVRGLAEEQIPVLGVVGVVGSTEEGAVDSIDKIIALRDELMKDGIYYYVHVDAAYGGYGRAIFLDEDNNFIPYEDLQDVHEEYGVFKEKKEHISREVYDAYKAIELAESVTIDPHKMGYIPYSAGGIVIQDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAAHHVLPLNVAGYGKLIGASIEGSHHFYNFLNDLTFKVGDKEIEVHTLTHPDFNMVDYVFKEKGNDDLVAMNKLNHDVYDYASYVKGNIYNNEFITSHTDFAIPDYGNSPLKFVNSLGFSDEEWNRAGKVTVLRAAVMTPYMNDKEEFDVYAPKIQAALQEKLEQIYDVK
What is the function of this protein?
Also involved in drug metabolism, being able to catalyze decarboxylation of levodopa (L-dopa) to dopamine.  In gut microbiota this enzyme is in fact exclusively responsible for the decarboxylation of levodopa, and thus reduces in situ levels of levodopa in the treatment of Parkinson's disease.  It was shown that abundance of bacterial tyrosine decarboxylase in the proximal small intestine - the primary site of levodopa absorption - contributes to interindividual variation in drug efficacy and can explain the requirement for an increased dosage regimen of levodopa treatment in Parkinson's disease patients.
What are the official names of this protein?
L-tyrosine decarboxylase, TDC, Levodopa decarboxylase, L-dopa decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. Tyrosine decarboxylase subfamily.
Protein: VATF_METST
Sequence: MKNDIAIMADPDTVTGFMLGGIKSGFPVHNKEEAKTTLKQLVDDEYSIIITTEKIGDELRDDITKYTGSKALPMIIEVPDKSGSHKRETDPMNDLIKRVIGVEMVK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: GHRA_SALA4
Sequence: MEIIFYHPTFNAAWWVNALEKALPHARVREWKVGDNNPADYALVWQPPVEMLAGRRLKAVFALGAGVDAILSKLNAHPEMLDASIPLFRLEDTGMGLQMQEYAVSQVLHWFRRFDDYQALKNQALWKPLPEYTREEFSVGIMGAGVLGAKVAESLQAWGFPLRCWSRSRKSWPGVESYVGREELHAFLNQTRVLINLLPNTAQTVGIINSELLDQLPDGAYVLNLARGVHVQEADLLAALDSGKLKGAMLDVFSQEPLPQESPLWRHPRVAMTPHIAAVTRPAEAIDYISRTITQLEKGEPVTGQVDRARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_ECO24
Sequence: MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLEIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWQEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQNELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: GSTF2_WHEAT
Sequence: MSPVKVFGHPMLTNVARVLLFLEEVGAEYELVPVDFVAGEHKRPQHVQLNPFAKMPGFQDGESLHIKSRAIAKYILRKYGGTAGLDLLGENSGIEELAMVDVWTEVEAQQYYPAISPVVFECIIIPFIIPGGGAAPNQTVVDESLERLRGVLGIYEARLEKSRYLAGDSISFADLNHIPFTFYFMTTPYAKVFDEYPKVKAWWEMLMARPAVQRVCKHMPTEFKLRARTRCLCTPRGCVPCRAGDDPTQEKRPPSRGWVIICPSTSSIPFQFQQHEESACASARASPDSLL
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase 2, GST class-phi.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Phi family.
Protein: AGRB3_MOUSE
Sequence: MKAVRNLLIYIFSTYLLVMFGFNAAQDFWCSTLVKGVIYGSYSVSEMFPKNFTNCTWTLENPDPTKYSIYLKFSKKDLSCSNFSLLAYQFDHFSHEKIKDLLRKNHSIMQLCSSKNAFVFLQYDKNFIQIRRVFPTDFPGLQKKVEEDQKSFFEFLVLNKVSPSQFGCHVLCTWLESCLKSENGRTESCGIMYTKCTCPQHLGEWGIDDQSLVLLNNVVLPLNEQTEGCLTQELQTTQVCNLTREAKRPPKEEFGMMGDHTIKSQRPRSVHEKRVPQEQADAAKFMAQTGESGVEEWSQWSACSVTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSSWSHCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAESRECYNPECTANGQWNQWGHWSGCSKSCDGGWERRMRTCQGAAVTGQQCEGTGEEVRRCSEQRCPAPYEICPEDYLISMVWKRTPAGDLAFNQCPLNATGTTSRRCSLSLHGVASWEQPSFARCISNEYRHLQHSIKEHLAKGQRMLAGDGMSQVTKTLLDLTQRKNFYAGDLLVSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDEENKEKWEDAQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVLTDINFPMKGRKGMVDWARNSEDRVVIPKSIFTPVSSKELDESSVFVLGAVLYKNLDLILPTLRNYTVVNSKVIVVTIRPEPKTTDSFLEIELAHLANGTLNPYCVLWDDSKSNESLGTWSTQGCKTVLTDASHTKCLCDRLSTFAILAQQPREIVMESSGTPSVTLIVGSGLSCLALITLAVVYAALWRYIRSERSIILINFCLSIISSNILILVGQTQTHNKSICTTTTAFLHFFFLASFCWVLTEAWQSYMAVTGKIRTRLIRKRFLCLGWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCGVVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQGFVIVMVHCILRREVQDAFRCRLRNCQDPINADSSSSFPNGHAQIMTDFEKDVDIACRSVLHKDIGPCRAATITGTLSRISLNDDEEEKGTNPEGLSYSTLPGNVISKVIIQQPTGLHMPMSMNELSNPCLKKENTELRRTVYLCTDDNLRGADMDIVHPQERMMESDYIVMPRSSVSTQPSMKEESKMNIGMETLPHERLLHYKVNPEFNMNPPVMDQFNMNLDQHLAPQEHMQNLPFEPRTAVKNFMASELDDNVGLSRSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQELNQKFQTLDRFRDIPNTSSMENPAPNKNPWDTFKPPSEYQHYTTINVLDTEAKDTLELRPAEWEKCLNLPLDVQEGDFQTEV
What is the function of this protein?
Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (PubMed:23628982).  Promotes myoblast fusion through ELMO/DOCK1 (By similarity).
What are the official names of this protein?
Adhesion G protein-coupled receptor B3, Brain-specific angiogenesis inhibitor 3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAAY4_SCHCO
Sequence: MAELLACLQSISAHAKDMMALARSRGATGSRPTPTTLPHFDELLPPNLDFVRTRLQEARLPPKAIKGTLSAYESACARWKHDLEEAFDRTAHSISPHNFQRLAQLRTRLYVEQVQKWLYEVLQVPERWKAEMEKQRAHINATMGPDKTTGPGKRSRPKFHSEYTPVLELYFHFNAYPTYADRRILAEKTGMLTRQITVWFQNHRRRAKGPLPRMSPTAKIPMEEFERQLENLARKIVPVLLPPTLRRFAPGNENKSLAAASRQSAGKSSKNAKRLSELEKAQQVPRKPSENAEAGPSSLGAMLARVMHNDSVSKKKSKKAKKEKASQQNVVCDVEMRDATATKEKRRKMKKLPRAAGQPFDVPMDVERADKASRKAMKKAKKSPRAFDSRAELAFAQAAYPSPSQYAYVHSRKPSAQKPSSDSPRKDFGQLGKGRPSSNSTSSTVPPHRVSSRLNAMRPPYAFPAPYNAAAVPLTFSVASSTQFAFATDNRSFGFAERTPRKATVPAACTLIDYLISKFAGLRLLCVEQSVSSRSISLSTSESGKLAGLRTEGLTTGEASGVQTHVDSYAARRAITYVPPSAPLDCVVHNLARALQLKQVRPMVLAQPVVQPDAFAPFIARAERRARRKERKQRKALEEKQAKKDRKERQKASRSQRDSPSMDADVQSRASSVASTSSLPARKSSKKSRKSKGESAASSRATSVASSVRTPSLSSTSSRRSSGMSMPGTPRPEQDLPIMATADFNFAGDEDVTMTPDLAAQLFGEDEDGAAALGQMQYEEFSPDMLTFTSTAGGALSDMTADVNMPDLGNAYTSQQSVDDMNWTGFGLDAQNSASPGLFGDESNTGLDWLLSHNLLGDTQMSDLSYTAPTSTPSQINILGSTYACELGGSDSLGTPFNMNDWTFGLGACDDGFAGFGNNLLGGTAVAV
What is the function of this protein?
Specifies A-alpha-4 mating-type.  May regulate the expression of genes specific to the homokaryotic cell type.
What are the official names of this protein?
Mating-type protein A-alpha Y4.
What are the subcellular locations of this protein?
Nucleus.
Protein: UCK1_BOVIN
Sequence: MASAGGGDCEGAGPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDHRQRKLVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKTVEVPTYDFVTHSRLAETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVQRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRAGANGRSHKRTFPEPGEHPAVLASGKRSHLESSSRPH
What is the function of this protein?
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate.  Does not phosphorylate deoxyribonucleosides or purine ribonucleosides.  Can use ATP or GTP as a phosphate donor.
What are the official names of this protein?
Uridine-cytidine kinase 1, UCK 1, Cytidine monophosphokinase 1, Uridine monophosphokinase 1.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
Protein: SYI_PHOLL
Sequence: MSDYKNTLNLPETGFPMRGDLAKREPNMLKRWYKDELYQVIRKAKAGKKTFILHDGPPYANGSIHIGHSVNKILKDIIIKSKGMAGYDSPYIPGWDCHGLPIELKVEQIIGKPGEKFSAAEFRAECRKYAKEQIEGQKKDFIRLGILGDWERPYLTMDFKTEADIIRALSRIIANGHLLKGAKPVHWCTDCRSSLAEAEVEYYDKTSPSIDVRFNAVDAVAVCEKFGVQAPEQPVSLVIWTTTPWTLPANRAIALHAEFNYQLVQIEGECLILAADLVESVMQRAGITSWTVLGHCAGSALELLRFKHPFMGFDSPVVLGDHVTLDAGTGAVHTAPGHGPDDFVLGQKYGLEVANPVGPNGCYLPGTYPSLDGMFVFKANDVVLNILSENNALLHLEKLQHSYPCCWRHKTPIIFRATPQWFVSMDQNGLRKQSLQEIKGVQWIPGWGQARIEAMVENRPDWCISRQRTWGTPMSLFVHKETEELHPRTIELMEEVAKRVEVDGIQAWWDLEPAELLGDDAANYVKIFDTLDVWFDSGSTHASVVDARPEFQGNAADIYLEGSDQHRGWFMSSLMISTAIKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTISPQDVMDKLGADILRLWVASTDYTGEIAVSDEILKRSADAYRRIRNTARFLLANLNGFDPEQHSVKPEEMAVLDRWAVGCAQAAQADIAKCYDKYDFHTVVQRMMQFCSVEMGSFYLDIIKDRQYTAKSDSLARRSCQTALYHIAEALVRWMAPILSFTADEVWNELPGKRAQYVFTEEWYGGLFGLAAGELMNDAFWADLLAVRGEVNKVLEQARADKHIRSSLEAAVTLYADNELADKLNSLGDELRFVLLTSQVVVADYEQAGEDAQQSEIGSLKIAFRKADGEKCPRCWHYAKDVGLVAEHAELCGRCVTNVAGNGEERKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_CMVC7
Sequence: MDKSESTSAGRNRRRRPRRGSRSAPSSADANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCKPGYTFSSITLKPPKIDRGSYYGKRLLLPDSVTEFDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVAAISAMFADGASPVLVNQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDALETDELVLHVDIEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: WFDC2_PIG
Sequence: MPACRLGLLVASLLLGLLLGLPPVTGTGAEKSGVCPAVEVDMNCTQECLSDADCADNLKCCKAGCVTICQMPNEKEGSCPQVDIAFPQLGLCLDQCQVDSQCPGQLKCCRNGCGKVSCVTPVF
What is the function of this protein?
Broad range protease inhibitor.
What are the official names of this protein?
WAP four-disulfide core domain protein 2, Epididymal secretory protein E4.
What are the subcellular locations of this protein?
Secreted.
Protein: YCJW_ECOLI
Sequence: MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEELQYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFFSEVLHAITAKAEEEGFDVILQTSHNPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYDIPVVVIGKVEGQYAHVYSVDTDNFGDSIALTDALIESGHQNIACLHAPLDVHVSVDRVNGYKQSLAAHNIAVRDEWIVDGGYTHETALKAARQLLSQSPLPEAVFATDSLKLMSIYRAAAEKNIAIPQQLAVVGYSNETLSFILTPAPGGIDVPTQELGQQSCELLFRLISGKPSPQNITVATHMTLK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YcjW.
Protein: YJP2_YEAST
Sequence: MPHLAAEAHTWPPHISHSTLSIPHPTPEHRHVFHKKDVKNKRNEEKGNNLLYVLFRTTVIKSSFRSLSTAGRELLFVVHQGHIGTGLIVFIICWRLCLRFLCRVSFQVTVYGGRSRMSA
What are the official names of this protein?
Putative uncharacterized protein YJL152W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: THSG_SACSH
Sequence: MAYLLREGTQRSTGNEVILNNIAVAKILLEMLKSSLGPKGLDKMLVEGQDITITNDGATIVKNMEVQHPTAKLLIETAKTVDTEVGDGTTSVVVLAGLLLEKAEDLLNQKIHPTVIIEGYRKALSSSLELLKSIADKISPEDRKIVHDLVYTTLSSKFFSTEHTLEKIINLVIEASLAVLDKRDGTYDLDIKNIKIVKVNGGEFDDSELVNGIVVDKEPTNENMPKRAENVKVMLADFPLKLEKTEISMKLGISDPTQIKGYLDEQTAYVKQMVDKIKAMGVKLFITQKDIDEVASYLMGKSGIIALKNVKRSDIELLSRATGAKIASSMKDANESDLGEAKLVEVRNLGKNKYLFIQSDKAKAVTVIIKGSNNMVTDEAERSLNDAFNSIRNLLLEPYIVAGGGAVEEELAKRLRENAGKVPGKEQLAFNAFADALEEYVSILSETAGMDPISALTEIRHKHANGLKNAGIDIVKARIYDNMLELKVIDSLKVKEQVLKSATEAATAILKIDDMIAAAPAKQQPQPQQPNPYLG
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit gamma, Chaperonin subunit gamma, HSP60 gamma subunit, Thermophilic factor 55 gamma, TF55-gamma, Thermosome subunit 3.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: MTLD_TOLAT
Sequence: MKALHFGAGNIGRGFIGKLLAESDAEVTFADANTQLVDQLNHSQEYHVRVVGDNQHTDVIRHIAAVQANSDDVINQIIKADIITTAVGPQVLAKIAATIARGLQLRFEQGNYAPVNIIACENMVRGTSQLKQAVLAELPAQYHAQLEEYVGFVDSAVDRIVPPAAANDEDPLAVTVESFSEWIVDKNQFRGDIPPVQGMELTDNLIAYVERKLFTLNTGHIVTAYLGKLAGYKTIREAIADEEIQQAVRQAMQQSGEVLVKRYGFDRQLHHAYIEKILTRFANPYLVDEIDRVGRQPLRKLGAEDRLTKPLLGTLEYGLPNDALLKGIAAALHYRNADDPQAVELQGWIEQDGVEAALLRATGLKADEPCVATIVAEYQRMA
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: MOBA_PSEA8
Sequence: MPDSALPPCSILLLAGGRGQRMGGRDKGLIEWQGLPLIAHLHRLVRPLTDDLIVSCNRNQERYAAYADRLVSDDSRDFPGPLAGIRAGLAVARHPWLLVLPCDAPRIDRALLETLLQAAGRTPARPWMLRCGGQWEPLFSLIPTHLAEEIEHAWRQGDRSPRHVLLPLGAEAIELAAGDPRLANLNTPELLANHRELK
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA_AGRRK
Sequence: MPSIYVQDVTLRDGMHAIRHQYGLDAITSIARALDRAKVAAIEIGHGDGLSGSSFNYGIGRHQDVEWIAAVADVLEHAKCTTLLLPGIGTVHDLKAAAALGVASVRVATHCTEADVAKQHIEAARALDLDVAGFLMMAHMNSPEGLAKQAQMMEAYGAHCVYVTDSAGALTMDGVRERVRALRQALKPETQVGIHVHHNLSLGVANAVVGVEEGAYRVDASLAGMGAGAGNTPIEVFAAVADRLGWQHGCNLFALMDAADDLVRPLQDRPVRVDRETLSIGYAGVYSSFLRHAENASKTYGVDVRDILVELGRRRMVGGQEDMIVDVALDLLASQQRA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: Y166_UREPA
Sequence: MESLKMSNIYLDELEGYSQKNIEDSIDSLIEPNQKPIHLCPFRILKGFIKITNTGEQSLLVNDKDFSTVWNIKASNEPIIAYWDKSFTYNFKGSLNYISKDYARIDPSNTTLKNNFKPYYFQAWVQNYSQANNVSTIVFNDKEHTVIKTITTVTLIVKYPSVYEDEIYQNEQGNLVSHKAKFKQWTTDMLKEYLFIIPDEHAQANQWLMVNEVIPFYSTTSKRYEGAQITLTNVNDLLTSSGNDILATIQPCQPGDGYLWPVIQNGKLTYDERKEKPLGVKSIQLLTNGPYALNSMLITGRTYNNDTRELSANKRLLLYKAKIPVASKFFNVSAPTSNYVYLYNAFFEIEKIYKDQYEKQKDFTFDHNANIKLNGGLLLNHKWDASNNALSYEDNRYPFKLWDEGFKIHASFFNFKLGGTGAQKGGSLTENAEQKKPLADAVVTGQVAGEVVSTVFESIGRNVSQGFNLNNLGLWSFNMGFAKTKAEQIKEATKIGLNNITMPPGTNLHTFLNHNAFMYDLIKYLPYSYKETIRQNLGELIDNTPLSLGKVRRGIVDILYPGWTKVEDATGYNMSNIWLNTRGFNFIAPCLPLELEVSNKLKADLINLDIFTNKPAKTFSPLGIPAIACCYHFDITDRFAKFVDDELKVFDTELIGQTTYRDGTYIRKDKKPLYWDSFCEALPPNTPLSYEPAVINIASGKREDVNRVKYPYVIDTIDIKGLGKCDIKLTAFSGFYSPDARLKDEFKNVYEAIFESNGKYTDDMSQWSNYINFSTLDEINSVGTKLSYPKPPVETDFLKNTKTNSDDGVNASLQTINETLYKVGDNSLLSATQYRKPRFYFYEPDSSKLANLFGYGSYTNKLNYLFGGSNLSDVIVANKVIAYSFVFKWDFNYREWLNLGSVNKTKRNLKLTFEIESNWIQKGWTNQFNVDNSFNQLITLLVLN
What are the official names of this protein?
Uncharacterized protein UU166.
Protein: H1_SOLPN
Sequence: MTAIGEVENPTVVQRPTEASKVKEQAPATDKKPRAPKEKKPKSAKAVTHPPYFQMIKEALLALNEKGGSSPYAVAKYMEDKHKDELPANFRKILGLQLKNSAAKGKLIKIKASYKLSEAGKKETTTKTSTKKLPKADSKKKPRSTRATATAAKKTEVPKKAKATPKPKKVGAKRTRKSTPAKAKQPKSIKSPAAKRAKKIAV
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: G6PI_BARHE
Sequence: MRYKSMGDSLSIRNEKAFEAALQALRRHAIKDGVYDIRRHFIEDEQRFSNFSLNLDDFLFDFSKCGVTFKTLQLLDDLAVAADVLGRRDAMFSGKAINTTEKRSVLHIALRLPADEVFMLDGTDLVHDIQGVLADMERFSDMVRDGSYKGNSGEKIIDIVNIGIGGSDLGPAMVTYALKPYHDGPNCHFVSNADSAHISDTLSVLNPATTLFVIASKTFTTAETIANAQVARQWIMSHLGKEAVCKHFIAVSSALDKVAEFGIDSSRTFRFWDWVGGRYSIWSAIGLVVMLAIGGQNFRQFLEGAQHMDRHFKTAPLRKNIPIRFALLGFWHRVVCGYASRAVIPYAQRLARFPAYLQQLDMESNGKQVSLDGKTLTFSSGPVVWGDSGTNGQHAFFQLLHQGTDVIPVEFILFIKGHEQNLHPMYDMLVANCLAQSKALMKGRSVEDARRMLLKSGIDERESENLALHKSFAGNRPNMMLVQDLLTPFALGRLIALYEHRIFVEGILMNINSFDQWGVELGKELANELLPILRGENKTNNRDSSTLGLLAHIQARRGE
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.