PharMolix/UniProtQA huggingface dataset:
Protein: NUOH_AQUAE
Sequence: MEAIAYSLAFTFLKIVIVFSLALGIGAYLTWFERKLAGHIQNRLGPTVVGKFGILQPLADALKLATKEVIIPRGADKPVYYAAVVMALVPSILLLTIIPFGPGFRVGNTYIEPIIADVNIALLLAFAFGSLSVYGTIFSGWASNSKYAFIGSLRKAAVVIAYEVVLGFSVLGVILLAGTLSTVGIVEAQIQKGVWFIFYQPVAFILYLFCMLAESGRVPFDIQEAEAELVTGYNVEYGGMKFGAFPLAEWYVNVIALSAIAVVLFFGGWDGPHIFGPLSPYFWFVFKTFALVFFTLWLHWTLPRFQAKDITEIAWKILLPIAILNVIITAVVVYAF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASTE_SHIF8
Sequence: MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQGALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDMNRMFGGRWQLFAESGETCRARELEQCLEDFYDQSKESVRWHFDLHTAIRGSLHPQFGVLPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSVRHFGALACTLELGKALPFGQNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFMPFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: KV5A2_MOUSE
Sequence: MHQTSMGIKMESHTLVFISILLCLYGADGNIVMTQSPKSMSMSVGERVTLTCKASENVVTYVSWYQQKPEQSPKLLIYGASNRYTGVPDRFTGSGSATDFTLTISSVQAEDLADYHCGQGYSYPYTFGGGTKLEIK
What are the official names of this protein?
Ig kappa chain V-V region MOPC 21.
Protein: MUTS_ECO7I
Sequence: MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRALLENVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIAPGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVQEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FLK_ECOLI
Sequence: MIQPISGPPPGQPPGQGDNLPSGTGNQPLSSQQRTSLESLMTKVTSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQLGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREATDRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWLQARQTLSQQNTPTLESLQMTLKQPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDILNQLYQRRVKGIDPRVMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWLVR
What is the function of this protein?
Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation.  Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion (T3S) system.  Plays a role in hindering to flip the flagellar T3S specificity switch from the rod and hook-type substrates to filament-type substrates prior to hook-basal body (HBB) completion possibly by preventing interaction of FliK with FlhB (By similarity).
What are the official names of this protein?
Flagellar regulator flk, Fluke.
What is the protein family that this protein belongs to?
Belongs to the flk family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: I2B_CONBE
Sequence: MMFRVTSVGCLLLVIVFLNLVVPTSACRAEGTYCENDSQCCLNECCWGGCGHPCRHPGKRSKLQEFFRQR
What is the function of this protein?
Modulator of potassium channels, specifically up-modulates the calcium and voltage-gated BK channels, has no effect on single channel conductance, but increases the open probability of BK channels.
What are the official names of this protein?
Kappa-conotoxin BtX, BeTx.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: M2_I02A2
Sequence: MSLLTEVETPTRTGWECKCSDSSDPLVVAASIIGILHLILWILDRLFFKCIYRRLKYGLKRGPSTGGVPESMREEYRQEQQSAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: FLAK_METMP
Sequence: MIEYIIGVIGLLLASVQDFRSREIEDYIWIVLAVFGILFAIYSAITLSNYSILINSISGFVICFILGYMMFLSGIGGGDGKILIGLGALVPKFQMPIYTSLGTLLNLNYIPNFPIMVFINGIFFMVFLPFVILFRNILNGARPKTGKEVILMFFGEKMKVKVAKEQKRLIMGQNDKINFFPASDDEDFSKYGDEEEIWVTPQIPLIIPITLSYLVTPIIGDRILDLLIPF
What is the function of this protein?
Cleaves the N-terminal leader peptide from preflagellins.
What are the official names of this protein?
Preflagellin peptidase, PFP.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family. Archaeal preflagellin peptidase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACT3_ECHGR
Sequence: LKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNCPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTVEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALYQPSFLGMEAVGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEITALAPSTMKIKIVAPPDGKYSVWIGGSILASLSTFHEMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-3.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: F161A_MOUSE
Sequence: MNFSDIYHSDEEYFRKLKDLKAVHEETMSKLEKMYQDKLNIKDIQAGFIRDGISDSSSSSASEKSCSHPALSVTSLSEPDLDGSSSLSTTTDEGLPDLEEKTPGESSAMVHAQELINNMWNDFSVEDYIQYDSDSRTAKKKRKKAKSLTPKITVPVPFEMTVREQNRREKALSARSDLETKLLKRDEDDAECKKKFRANPVPSCVLLPLYEDLVKQSEERRKKARERNRAALLASLKPFKFIAREEQKQAVREKKLRDLFRAKRKTNQFKAKPVPRFIYRPAASDKPKEEELYGDSRMLPKVRDLLQNSPWPSRSACRRFRDPRSPAKPRGKHRRRCLRRDGDLEKWKEPFSEYSFLKCPMLCEECCLHESPCDSDKRQKLLADIRADEEILRETRRPGRSPRRKSPGRSSNPKPRPHECSPPMPTASSRGREQAIRRSEKARMREYWQELEEQEEKLQKRPMLFERVTQVVFIG
What is the function of this protein?
Involved in ciliogenesis.
What are the official names of this protein?
Protein FAM161A.
What is the protein family that this protein belongs to?
Belongs to the FAM161 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Note=Localized in the region between the outer and inner photoreceptor segments, corresponding to the photoreceptor connecting cilium.
Protein: DOPP1_CALJA
Sequence: MAADGQCSLPASWRPVTLTHVEYPAGDLSGHLLAYLSLSPVFVIVGFVTLIIFKRELHTISFLGGLALNEGVNWLIKNVIQEPRPCGGPHTAVGTKYGMPSSHSQFMWFFSVYSFLFLYLRMHQTNNARFLDLLWRHVLSLGLLAAAFLVSYSRVYLLYHTWSQVLYGGIAGGLMAVAWFIFTQEVLTPLFPRIAAWPISEFFLIRDTSLIPNVLWFEYTVTRAEARNRQRKLGTKLQ
What is the function of this protein?
Required for efficient N-glycosylation.  Necessary for maintaining optimal levels of dolichol-linked oligosaccharides.  Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate.  Does not act on phosphatidate (By similarity).
What are the official names of this protein?
Dolichyldiphosphatase 1, Dolichyl pyrophosphate phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the dolichyldiphosphatase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YF009_HUMAN
Sequence: MQTCSGKGIKMAFLDVQSSSTPQSLPLLLFSHREGGGRGAGDPGAPAVVPAPVSAPRPASSPARSESRSPPLTLISRHITCCSCESPGDVLLSGRGGGGGGGGGARTGGGEGEDRRPRPDFSRVTAVAIPGWMEVESPPHPPPQPQVCPTPSQGAPGHGRAGLPEGKGPGGRDWLRSQSSRCSRATLFGHRAPSPAAPRRGRLPAPGFPSLHSAVSLF
What are the official names of this protein?
Putative uncharacterized protein FLJ45840.
Protein: CAPP_SHELP
Sequence: MTDMYASLRSNVGTLGQILGDTIRTHMDEPFLDKIEQIRHLAKSSRQGNDTAREQMLTLLAALPDEELVPFAKAFNQFLNLANIAEQFHTISRNCDELVCVPDPVDQLLGRMLNGRIDQDKMLECLQTLDIDLVLTAHPTEISRRTLIQKYSAVVDCLATMENPQLTEREKKQNHLRLRQLIAQIWHTNEIRHERPTPVDEARWGLSTIEASLWQAIPDFLRQLNEQVEERTGKQLPSDIAPIRFSSWMGGDRDGNPFVTAKVTQEVLDRNRHTAARLYLKDVVLLVNELSMEEANEELLALTDNSHEPYRVVLRELRQKLRDTIDYLNARLEGHSPEVDLDSLIWHEDDLKQPLTLLYRSLTESGMSLIANGLLLDMLRRLACFGIHMLRLDIRQDAQRHSDVIAELTRYLGLGDFDHWDEHEKQAFLLRELSGKRPLIPHNWEPSAEVAEVISTVRLIASQSPKALGSYVISMASQPSDVLTVLLLLKEAGCQHPMRVVPLFETLEDLNNAASCISALFAIDWYRGYCKGSQEVMIGYSDSAKDAGVMAAAWAQYSAQEKLVKVCNQADIKLTLFHGRGGTIGRGGGPAHKAILSQPPGSVDGRIRVTEQGEMIRFKFGLPKLAVQSLALYTSAVMEATLLPPPEPKPEWREAMERLASDSVTAYRAIVREEPDFVAYFRAATPEVELGKLPLGSRPAKRRVDGGIESLRAIPWIFAWSQNRLMLPAWLGAGEALQQAADRGELTLLREMEQQWPFFETRISMLEMVYAKAEPNLAKYYETCLVPQELHHLGEALRSRMATGIKVVLELTQSDALMSHTPWNRESVELRNPYIDPLNFLQAELLARTRKEQAGSSNVELALMLTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: PURT_SHIFL
Sequence: MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSKSLFREAVAAIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQNVTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVVLATSESVVDAIERAKHAAGQVKVQG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: FABH_STAAC
Sequence: MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASLKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGGGLTWGAMTIKWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYRI_DICDI
Sequence: MGQLLSFINGNDHTEQIFIDFEHAQPSDDERELHKTVNEVLIRGPAIIDKLLAYAGCNEFIRRAITNPGPETEDAAWEAVLPSVDQLQEFYDFSLELETCFPKLLVALCKNDPKASLSNQQALAKQLADIFDFVLKFDDAKMVNPAIQNDFSYYRRTLNRMKLTKKDANIKIRDELANRMSLFFAYPTPMMKVLSETTVKFLSQDTTVPRDNVTTALATMANVCHDMVEKKKFTQDDLNMFCLRAMVGSIILFDHIHPQGAFVKKSPVNIKPCIVTLKDSNTQSSPGLLNALRFTTIHLNDVDTPGAIKQLLLLD
What is the function of this protein?
May negatively regulate RAC1 signaling and RAC1-driven cytoskeletal remodeling.
What are the official names of this protein?
CYFIP-related Rac1 interactor homolog.
What is the protein family that this protein belongs to?
Belongs to the CYRI family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: COAE_LACLA
Sequence: MVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPGGKLYKAIVETYGLDFIADNGQLNREKLGALVFSDSKEREKLSNLQDEIIRTELYDRRDDLLKKMTDKSVSKNFDSKSQGKNLSVNKPIFMDIPLLIEYNYTGFDEIWLVSLPEKIQLERLMARNKFTEEEAKKRISSQMPLSEKQKVADVILDNFGTIEALKKQIQRELARIEEQK
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFPL_ECOUT
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: GH_HHV6Z
Sequence: MLFRLWVFVLLTPCYSWRPWTISDESHCKNGNSENPIVRPGFITFNFYTKNDTRIYQVPKCLLGSDITYHLFDAINTTESLTNYEKRVTRFYEPPMNDILRLSTVPAVKQFNLDHSIQPQIVYSLNLYPSHGIYYIRVVEVRQMQYDNVSCKLPNSLNELIFPVQVRCAKITRYAGENIYTHFFTPDFMILYIQNPAGDLTMMYGNTTDINFKAPYRKSSFIFKQTLTDDLLLIVEKDVVDEEYRFISDATFVDETLDDVDEVEALLLKFNNLGIQTLLRGDCKKPDYAGIPQMMFLYGIVHFSYSTKNTGPMPVLRVLKTHENLLSIDSFVNRCVNVSEGTIQYPKMKEFLKYEPSDYSYITKNKSIPVSTLLTYLATAYETNVTISRYKWSDIANTLQKIYEKHMFFTNLTFSDRETLFMLAEIANFIPADERMQRHMQLLIGNLCNPVEIVSWAHMLTADKAPNLENIYSPCASPVRRDVTNSFVKTVLTYASLDRYRSDMMEMLSVYRPPDMARVAAIQCLSPSEPAASLPLPNVTFVISPSYVIKGVSLTITTTIVATSIIITAIPLNSTCVSTNYKYAGQDLLVLRNISSQTCEFCQSVVMEYDDIDGPLQYIYIKNIDELKTLTDPNNNLLVPNTRTHYLLLAKNGSVFEMSEVGIDIDQVSIILVIIYVLIAIIALFGLYRLIRLC
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: PYRG_ZYMMO
Sequence: MARFIFITGGVVSSLGKGLMAASLAALLQERGFRVRIRKFDPYLNVDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFSGVPSRRSDNITSGRIYQNIIAKERRGDYLGATVQVIPHVTDAIKDFARDDTDDLDFVLCEIGGTVGDIESLPFIEAIRQLKNDLGRGNVVFVHLTLVPYIAAAGELKTKPTQHSVRDLTSFGIQPDVLVCRTEHPLPDSERSKIALFCNVPKEAVIPALDAKSIYDVPLHYHAEGLDKAVLSAFGLNIETPLDLHRWKEISDRLANPEGEVTIGVVGKYVGLQDAYKSLHEALVHGGIANRVKVNIVWLDAEMFEGNNPEAAEALSSLHAILVPGGFGERGSEGKIAAVKFAREHKVPFFGICLGMQMACIEGARNTAGLKKASSSEFGPSEEPVIGLITEWERDGEREERAADGDLGGTMRLGAYPAVLKAGSQVAEIYNSREITERHRHRYEVNIHYKEPLEKGGLVFSGMSPDGLLPEIVERPDHPWFIGVQFHPELKSKPFDPHPLFSDFVAAALKQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DAPA_ACET2
Sequence: MRKPIFTGAGVAIITPFTENGVNYDKLGELIEFQIREGIDSIIICGTTGEASTMPDEEHKAVIKYTVEKVNKRVPVIAGTGSNDTIHAVELSKYAEEVGADAILSVTPYYNKTTQKGLYEHFKLIAESIKIPVVLYNVPGRTGLNIEPKTVKQLAEIENIVAIKECNINQVGEIISICPPDFTVYSGNDDMVVPLLALGGKGVISVMANIIPKKTHELVATFLDGNVEESRKIQLSLLNLIKALFIEVSPIPVKAAMNLMGMEVGKCRLPLTDMTEKNFEILKQTLKDYGLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGLRB_ASPFN
Sequence: MQLLQSSVIAATVGAALVAAVPVELEARDSCTFTSAADAKSGKTSCSTITLSNIEVPAGETLDLTGLNDGTTVIFSGETTFGYKEWEGPLISVSGTNIKVQQASGAKIDGDGSRWWDGKGGNGGKTKPKFFYAHKLDSSSITGLQIYNTPVQGFSIQSDNLNITDVTIDNSAGTAEGHNTDAFDVGSSTYINIDGATVYNQDDCLAINSGSHITFTNGYCDGGHGLSIGSVGGRSDNTVEDVTISNSKVVNSQNGVRIKTVYDATGTVSNVKFEDITLSGITKYGLIVEQDYENGSPTGTPTNGIKVSDITFDKVTGTVESDATDIYILCGSGSCTDWTWSGVSITGGKTSSKCENVPTGASC
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity).
What are the official names of this protein?
Probable endopolygalacturonase B, Pectinase B, Polygalacturonase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF3_STRGC
Sequence: MNLQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEVLGIASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKEDIELLNEAGNEFSEEAILAGDLTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGEIVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKTAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSAKNVMKQKSFHKGIEQLVQEGAIQLYTNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMTPMGKKTVRWISPDDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVKLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB_BPT7
Sequence: MAKKIFTSALGTAEPYAYIAKPDYGNEERGFGNPRGVYKVDLTIPNKDPRCQRMVDEIVKCHEEAYAAAVEEYEANPPAVARGKKPLKPYEGDMPFFDNGDGTTTFKFKCYASFQDKKTKETKHINLVVVDSKGKKMEDVPIIGGGSKLKVKYSLVPYKWNTAVGASVKLQLESVMLVELATFGGGEDDWADEVEENGYVASGSAKASKPRDEESWDEDDEESEEADEDGDF
What is the function of this protein?
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks (PubMed:16807232, PubMed:8617248, PubMed:9079662, PubMed:11222583).  Coats the lagging-strand ssDNA as the replication fork advances and stimulates the activities of viral DNA polymerase and primase/helicase (PubMed:8617248).  Coordinates simultaneous synthesis of leading- and lagging-strands (PubMed:9651583).  Together with DNA primase/helicase, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions and mediates homologous DNA strand exchange (PubMed:8617248).  Promotes also the formation of joint molecules (PubMed:8617248, PubMed:9079662).  Disrupts loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation (PubMed:1634538).
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB protein, 2.5 protein, Gene product 2.5, gp2.5.
What is the protein family that this protein belongs to?
Belongs to the Teseptimavirus single-stranded DNA-binding protein family.
Protein: LOX_ROSS0
Sequence: MESADLRDPDGMPVTLSDFEIDAAGRLSADLLAYLEGGAEAGQSVTENRAAFGRIGLLPKLLSPCAGGHTRTTILGKQAPHPIMVAPMAFQNLFHPQGESATAMAAAAQDATMVLSCQTSTPPEDIATIPGRRWFQLYMQADHEATMALVTRAVDCGADALVVTLDAPINGLRDREVAAGFTLPDDVRPVMLDVLPQPPRPHLRDGQSVVFDGMMVFAPTADDLARLIADSPVPVIVKGCLRPADATRLIDLGAQGIIVSNHGGRVLDTVPAPITQLAAVVDAVAGAVPVYVDGGIRRGSDVFKALALGAQAVLVGRPVMHGLIVDGPRGASQVLRRLRDELEVTMALCGCATVADITPDLLTGFSGTGS
What is the function of this protein?
Catalyzes the oxidation of (S)-lactate (L-lactate) to pyruvate, with a reduction of O2 to H2O2.  Is also able to use glycolate and to a lesser extent 2-hydroxyoctadecanoate as substrate.
What are the official names of this protein?
L-lactate oxidase, LOX, (S)-2-hydroxy-acid oxidase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.