PharMolix/UniProtQA huggingface dataset:
Protein: ARGI_MEDTR
Sequence: MSTIARRGFHYMQRLNSANVSPALLEKAQNRVIDAALTFIRERAKFKGELMRSLGGVAATSSLLGVPLGHHSSFHEGSAFAPPRIREAIWCDSTNSTTEEGKNLRDPRVITNVGDVPIEEIRDCGVDDKRLANVISESVKLVMDEDPLRPLVLGGDHSISFPVVRAVSEKLGGAVDILHFDAHPDLYHDFEGNYYSHASPFARIMEGGYARRLVQVGIRSITNDVREQVKKYGVETHEMRTLSRDRPILENLKLGEGVKGVYVSIDVDSLDPSIAPGVSHHEPGGLLFRDILNILQNLQGDIVGGDVVEYNPQRDTYDGITALVAAKLVRELAAKMSK
What is the function of this protein?
Catalyzes the hydrolysis of L-arginine to urea and L-ornithine (Probable).  The latter can be utilized in the urea cycle or as a precursor for the synthesis of both polyamines and proline (Probable).  Possesses agmatinase activity.  Catalyzes the formation of putrescine from agmatine (By similarity).
What are the official names of this protein?
Arginase, mitochondrial, Agmatinase ARGAH, Arginine amidohydrolase, MtARGAH.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL7_LIBAC
Sequence: MSDIESIVEKLSSLTLIQAAELSKRLEEEWGVSASAPVAAVAPAVXXDVAVAEKTEFEVFLESFDAKSKISVIKEVRSITDLGLKEAKELVEALLKSLRTGVSKDEANELKKKLEAAGATISLR
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: STPS1_SALMI
Sequence: MATTQAQIQRPIANFSPSLWGDQFIKNDPGAKAAEKHCKAVEELKKEVMNMITAAGSNLVEAMNLIDTLERLGISYHFEKEIDQKLKHFFNLNKDYSDESYDLYTVSLHFRLFRQHGHRISSDIFGRWIDESGKFKEGLKTDGKGLLSLYEASYLRTRGETILDDALEFATATLNSIAPHLESPLSKQVVHALIQPLHYGNPRIEAHNFISIYEENQDKNEFLLRFAKLDYNLLQMLHKEELNEVSRWWKELDLVSKLPYARDRVVECFFWAMGVYHEPQYSRARIMLTKTITMTSIIDDTYDAYGVIEELDIFTEAIERWNMEEMKKLPEYIQPFYKALLELYEQFEEELAEEGRSYAAHYAIESLKELVRSYHVEAKWFIQGYLPPFEEYLKNALITCTYCYHTTTSLLGVESAVEEDFEWLANKPKMLVAGLLICRVIDDIATYEVEKERGQSATGIESYMRDNNATIEEAVAKFFEIATDAWKDINEECLMPSPYSRDVLMRILNLERIIDVTYKGNEDGYTQPEKVLKPHIIALFVDPIKM
What is the function of this protein?
Sesquiterpene synthase that catalyzes the conversion of farnesyl diphosphate to (-)-5-epi-eremophilene.
What are the official names of this protein?
(-)-5-epieremophilene synthase STPS1, Sesquiterpene synthase 1, SmSTPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: RMD5A_XENLA
Sequence: MDQCGTVERELEKVLHKFGGYGQLCERSLEELIDYAGGLRREILQAAEQDGELSGTLSLVLTQCCKRIKDTVQKLASDHKDIHSSVSRVGKAIDKNFDADISSVGIDGCWQTDSQRILSEVMVEHFFRQGMLDVAEELCQEASLSIDASQKEPFVELNRILEALKVRVLRPALEWAVSNREMLMAQNSSLEFKLHRLYFISLLMGGTVNQQEALQYAKNFQPFAENHQKDIQVLMGSLVYLRQGIENSPYVHLLDANQWADICDIFTRDACSLLGLSVESPLSVSFSAGCVALPALINIKAVIEQRQCSGVWNQKDELPIEVDLGKKCWYHSIFACPILRQQTTENNPPMKLVCGHIISRDALNKMFNGSKLKCPYCPMEQSPGDAKQIFF
What is the function of this protein?
E3 ubiquitin-protein ligase component of the CTLH complex.
What are the official names of this protein?
E3 ubiquitin-protein ligase RMND5A, Protein RMD5 homolog A.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm.
Protein: NUOD_POLAQ
Sequence: MTKIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAETRTWIQNVPYMDRLDYVSMMSNEHAYVLAIEKLLQVDVPLRAQYIRVMFDELTRLLNHLLWIGCHGLDVGAMAVFLYAFRDREDIFDMYEAVSGARMHAAYYRPGGVYRDLPDQMAQYSKSKIRSASAIKRLNENRSGTLLDFIDQFTNGFDANVDEYCNLLTDNRIWKQRLVNIGIVTPERALQLGFTGPMLRGSGIEWDLRKKQPYEVYDRLDFDIPVGVNGDSYDRYLVRMEEMRQSNRIIKQCVAWLKANSGPVMSDNHKVSPPKRVDMKTNMEELIHHFKLFTEGMHVPNGEAYSAVEHPKGEFGIYLISDGANKPYRMKIRAPGFVHLSAMDEMSRGHMLADAVTIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: WNT2_LOXAF
Sequence: MNAPLAGIWPWLPLLLTWLAPEVSSSWWYMRATGGSSRVMCDNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTAKDSKGTFDWGGCSDNIDYGIRFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSPGTAGRVCNLTSRGMDSCEVMCCGRGYDTSRITRMTKCECKFHWCCAVRCQDCLEALDVHTCKAPKSADWAAPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity).  Functions as upstream regulator of FGF10 expression.  Plays an important role in embryonic lung development.  May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: HPXO_MYCVP
Sequence: MKVVIVGAGMGGMSAAIALRQIGIDTVVYERVTENKPVGAAISVWSNGVKCLNYLGLQEETAELGGKVETMSYVDGHTGDTMCRFSMHPLIEQVGQRPYPIARAELQLMLMKAYGIDDINFGMKMVGVENDTAGSAAKATFADGTTVSADVIIGADGAGSITREYVLGGPVSRRYAGYVNYNGLVSTDDAIGPATEWTTYVGDGKRVSVMPVSDDRFYFFFDVVEPQGSPYEEGRVREVLRAHFAGWTPGVQTLIDTLDPLATNRVEILDLDPFHTWVKGRVAVLGDAAHNTTPDIGQGGCSAMEDAIALQWAFKDHPDDVHAALAAYQSARTERAADLVLRARKRCDVTHAKDPQVTSRWYDELRNEDGTNIIRGIVGNIVGGPLTPVTAATEG
What is the function of this protein?
Catalyzes the hydroxylation of urate to 5-hydroxyisourate (HIU).  Is likely to be involved in the urate degradation pathway to allantoin.  Prefers NADH over NADPH as the electron donor.
What are the official names of this protein?
FAD-dependent urate hydroxylase, Flavoprotein urate hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent urate hydroxylase family.
Protein: ARV1_SCHPO
Sequence: MKCVECGAEVDSLYTYYGRGTSNIRLAQCKNCKQFADKYIELDVVLISMDVILMKPQVYRHLLFNSLSARTFRNVVNFCILISLFNVFLVWSRLEKRAALFPYFTPAQAFLSQPIIRQYLTLLLICLVETTVYQISVVLLLCLTMGWKSWTSASGAVILSSSTRMLPVFMVIWDYDLSIAATVVEWVVLFSNVDALCILTGSRRYFKIGLIVLFASLVRSIVVYIFLHLTGLSQIQPSTPCDGFQHFVNLLCVYFRSITLTAQTAV
What is the function of this protein?
Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.  Regulates also the sphingolipid metabolism (By similarity).
What are the official names of this protein?
Protein arv1.
What is the protein family that this protein belongs to?
Belongs to the ARV1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: GCSPA_KORVE
Sequence: MRYLPKSQSDRDQMLRELGCATIDDLFAPIPAEYRLTRDLAIPRQYGESEILDFFKQRASENANGYSIFIGAGAYNHYRPVVIDSLISRGEWFTAYTPYQPEISQGTLQAIFEFQSMICELTGMEVANASMYDGSTGAAEAIMMAVRLTGRHSAIIANTVHPEYREVIATYAQHQGLPISHVGYNAETGRVDIKALEAAITDQTAAVLIQSPNFFGTIEDVAAIADLVHKKGALLVVSISEALSLGLIKPPSEADIISMESQSFGVPLGYGGPYVGVIATKEKFVRQIPGRLCGQTVDRNGKRGFVLTLSTREQHIRREKATSNICTNQALIALIASIFMTVYGKQGLRELAKQNLAKTAYAVSAFEKAGAKVLFKNSPFFNEFVVQTKSDSRELNDKLISDKIIGGFPLKKFYPELGNSAVWCVTELNAKAAIDAAAKGVAQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: GREB_PSEPK
Sequence: MSTNIITTEGHEALKKELDHLWRVYRPEITQKVAWAASLGDRSENADYQYNKKLLREIDRRVRYLRKRLEDVKVVAYSPEQEGKVFFGAWVEIENDEGETMKFRIVGYDEIYGRNDYISIDSPMARALLKKEEGDEVVVHTPTGEATWYVSSIRYGQGVSTD
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreB releases sequences of up to 9 nucleotides in length.
What are the official names of this protein?
Transcription elongation factor GreB, Transcript cleavage factor GreB.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family. GreB subfamily.
Protein: NMD3A_MOUSE
Sequence: MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQDGGRAGAQRDEPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGTETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESIINITANLSSTKDLLSFLQVQLENIRNSTPTMVMFGCDMGSIRQIFEMSTQFGLSPPDLHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFHHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPCSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNMGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQTHQDIPLPPRRRELPASLTTNGKADSLNVARNSVMQELSELEKQIQVIRQELQLAVSRKTELEEYQRTNRTCES
What is the function of this protein?
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium.  Mediated by glycine.  During the development of neural circuits, plays a role in the synaptic refinement period, restricting spine maturation and growth (By similarity).  By competing with GIT1 interaction with ARHGEF7/beta-PIX, may reduce GIT1/ARHGEF7-regulated local activation of RAC1, hence affecting signaling and limiting the maturation and growth of inactive synapses (PubMed:24297929).  May also play a role in PPP2CB-NMDAR mediated signaling mechanism (By similarity).
What are the official names of this protein?
Glutamate receptor ionotropic, NMDA 3A, GluN3A, N-methyl-D-aspartate receptor, N-methyl-D-aspartate receptor subtype 3A, NMDAR3A, NR3A, NMDAR-L.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3A/GRIN3A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. Requires the presence of GRIN1 to be targeted at the plasma membrane.
Protein: LBD16_ARATH
Sequence: MASSGNGTTAGTGSPCGACKFLRRKCASDCIFAPYFSSEQGAARFAAIHKVFGASNVSKLLLNVPIHDRCEAVVTIAYEAQARLHDPVYGCVSHIFALQQQVAFLQSQVMQMKAQIAGHQTSAAGDLRHSSESTNQFMTWQQTSVSPIGSAYSTPYNHHQPYYGHVNPNNPVSPQSSLEESFSNTSSDVTTTANVRETHHQTGGGVYGHDGIGFHEGYPNKKRSVSYCSSDLGELQALALRMMKN
What is the function of this protein?
Transcriptional activator (PubMed:19717544, PubMed:22974309).  Involved in lateral root formation.  Regulated by the transcriptional activators ARF7 and ARF19 (PubMed:17259263).  Functions in the initiation and emergence of lateral roots, in conjunction with LBD18, downstream of ARF7 and ARF19 (PubMed:19717544, PubMed:23749813).  Acts downstream of the auxin influx carriers AUX1 and LAX1 in the regulation of lateral root initiation and development (PubMed:26059335).
What are the official names of this protein?
LOB domain-containing protein 16, ASYMMETRIC LEAVES 2-like protein 18, AS2-like protein 18.
What is the protein family that this protein belongs to?
Belongs to the LOB domain-containing protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COKA1_HUMAN
Sequence: MSSGDPAHLGLCLWLWLGATLGREQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGLWE
What is the function of this protein?
Probable collagen protein.
What are the official names of this protein?
Collagen alpha-1(XX) chain.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RL6_NITOC
Sequence: MSRIADNPVSIPKGVEVTLSGDNDIKVKGAKGSLAFAIHPLIQVVQDGETLRFSAKSTDKRVNALRGTTRALINNMVQGVSQGFERRLQLVGVGYRAQLQGRKLVLSLGYSHPVEFTAPEGLTIEVPSPTEIIVKGYDKQQVGQAAANIRRFRPPEPYKGKGVRYADEVVVRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MCRI1_XENTR
Sequence: MTSSPVSRVVYNGKRPASNTRSPSSNEIFTPAHEENVRFIYEAWQCVERDLRNQVSGMDRGVVEEYVEKNPSNSLKSFKPIDLNDLKRRTVQDPKKS
What is the function of this protein?
May play a role in the regulation of the epithelial-mesenchymal transition.
What are the official names of this protein?
Mapk-regulated corepressor-interacting protein 1, Protein FAM195B.
What is the protein family that this protein belongs to?
Belongs to the MCRIP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, Stress granule.
Protein: IF4A1_MACFA
Sequence: MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTASAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-I, eIF-4A-I, eIF4A-I, ATP-dependent RNA helicase eIF4A-1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: SULP3_CAEEL
Sequence: MYKKMSLRQLFSDRPPLNAVLQEKAQKLRYACSPSKCIHSLLSFLPIITWLPKYDWSHSFFGDLSGGLTMAVFSVPQGIALASITGVPPVYGLYTAIFPSFLYIFFGTSKHNALGGFAVLSLMTHGAIEKVMLRTATSYNATAYVNHTLDELLDKENETALISNTTLMQILGNETSFVEEVTMEMWTEGVTPVKQIHVATTIIFLAGVIQVFMGVFRLQYLTSLFSEQVMSGFVVGGGIHVFFAQIGNMLGIELPRRSGPGYLYYRIWDLVENLDNVHIPTVCISLSSFLFLVFGKEYLAPWLNSAFNYPVPFELVLVVVGITATNYAELSLRHDVKVVGNIPTEFPPPSLPRFDLIRHIGLNAAAIAITAVAIHITVAKVVEKRYKYKINHGQELYALGFVGVLSSFFPVFPVTSGFARSVVGAAVGGSTQLTCLFSSLALLSVILCIGPALEYLPQCILSAMIIFAQKGMLEKFGELKSLWPVFKIDFTIWLMSFFLTVCYDMGEGLLMAIGFAVLTTIIRTQRPKWHFLSRDDDTENYKETKKRDLERIQGNVCIFRMDAPLIFTSSDRFTMSVWQCVKKWERCKSESFVTIEQMNSDRSADIFDSKLKSARRRWKRDQKSENRCKLVIDCDGFPYVDYLGLSTLKSVYVDLQAAGIQCFFVVQKSDLKKLFRATDFYEVVDESKVFNKVGDAVKAAEQHISSPKTTKEILTALASIATTDTVLIDEESSDSNDNDDAEIQERITEESENSEEVMSETSVSIEDATSLTSSRNSINSEE
What is the function of this protein?
Possible sulfate transporter.
What are the official names of this protein?
Sulfate permease family protein 3.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VPS18_MOUSE
Sequence: MASILDEYEDSLSRSAVLQTGCPSVGIPHSGYVSAHLEKEVPIFTKQRVDFTPSERITSLVVSCNQLCMSLGKDTLLRIDLGKASEPNRVELGRKDDAKVHKMFLDHTGSHLLVALSSTEVLYMNRNGQKARPLARWKGQLVESVGWNKAMGNESSTGPILVGTAQGQIFEAELSASEGGLFGPAPDLYFRPLYVLNEEGGPAPVCSLEAERGPDGRGFVIATTRQRLFQFIGRAVEDTEAQGFAGLFAAYTDHPPPFREFPSNLGYSELAFYTPKLRSAPRAFAWMMGDGVLYGSLDCGRPDSLLSEERVWEYPAGVGPGANPPLAIVLTQFHFLLLLADRVEAVCTLTGQVVLRDHFLEKFGPLRHMVKDSSTGHLWAYTERAVFRYHVQREARDVWRTYLDMNRFDLAKEYCRERPDCLDTVLAREADFCFRQHRYLESARCYALTQSYFEEIALKFLEARQEEALAEFLQRKLAGLKPTERTQATLLTTWLTELYLSRLGALQGDPDALTLYRDTRECFRTFLSSPRHKEWLFASRASIHELLASHGDTEHMVYFAVIMQDYERVVAYHCQHEAYEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGEAQQVSQAIRYMEFCVNVLGETEQAIHNYLLSLYARGQPASLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQREMEEATASAQRIRRDLQELRGRYGTVEPQDKCSTCDFPLLNRPFYLFLCGHMFHADCLLQAVRPGLPAYKQARLEELQRKLGAAPPPTKGSVKAKEAEAGAAAVGPSREQLKADLDELVAAECVYCGELMIRSIDRPFIDPQRYEEEHLSWL
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways.  Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.  The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes.  The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (By similarity).  Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:14517315, PubMed:22854957).  Involved in dendrite development of Pukinje cells (PubMed:22699122).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 18 homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS18 family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Cytoplasmic, peripheral membrane protein associated with early endosomes and late endosomes/lysosomes.
Protein: PGK_LEPBA
Sequence: MKLPLLEEQNLKGKRVFVRVDFNVPVENGKATDRTRIEKTLPTLELLISKGAKIILGSHLGRPKGGPEPKYSMKPVFDVLSELVKTKVSFSESVIGSDVVKMTNALGEGEILLLENLRFHKEEEENVASFCKELAKLADVYVNDAFGTAHRAHASTEGVAHLLPAFAGLLMRKEIEVLSGLLAKPERPFVAIVGGSKVSSKFAILKNLLEKVDHLLIGGGMAYTFLKSRAVPVGKSLVEPEFESQAFQLIDRAGIQGVDLQIPVDHIIADAFDPNAKTKSVDKMGIIDGWMGMDIGPKTIDNYVKAIKDAKTILWNGPMGVFEMDKFSKGTIEIAKAISKSKAKTVVGGGDSIAAVNKAGVADKITHISTGGGASLEFLEGRTLPGVQCLLPKEEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_LEVBA
Sequence: MADNQSVLSVSIVTPDGQVYNEQGDLLIVTTKSGQLGIMPNHVPVIASLEVEEARIKRGENEDEIAVNGGFLEFSGNVATIVADSAERQDDIDVNRAENARERAEATIKKAQEAHDADTLARAEVALRRAVNRINVAKH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRMD_LEUCK
Sequence: MRIDVLSLFPDMFTPLKQSILGKAIDKGALDFHVTDFRDYTENKHNNVDDYPFGGGAGMLLMAQPIFDAMAAVEKAAGDKGHVVLLDPAGRKFDHHVAEELAQKSHLTFIAGHYEGYDERIRELVDDEISLGDYVLTGGELGAMVIIDATARFLPDVLGNQVSAEEDSFQDNLLEFPQYTRPADFRGRKVPDVLMSGNHAKIAEWRLKESLRRTWQRRPDLLENRVLTQTERDLLDDIKHE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.