PharMolix/UniProtQA huggingface dataset:
Protein: FLI1_BOVIN
Sequence: MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWMNQPVRVNVKREYDHMNGSRESPVDCSVSKCGKLVGGGESNTMSYTSYVDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKLNKEDFLRATSLYNTEVLLSHLTYLRESSLLPYNTTSHTDPSSRLNVKEDPSYDSVRRGGWGSNMNSGLNKSPPLAGAQTMSKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYVPSYHTHQQKVNFVPPHPSSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
What is the function of this protein?
Sequence-specific transcriptional activator.  Recognizes the DNA sequence 5'-C[CA]GGAAGT-3' (By similarity).
What are the official names of this protein?
Friend leukemia integration 1 transcription factor, Proto-oncogene Fli-1.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 3L257_OPHHA
Sequence: MKTLLLTLVVVTIVCLDLGYTRICHKSSFISETCPDGQNLCYLKSWCDIFCGSRGERLEFGCAATCPEVKPGVNIECCSTDNCNPHPKLRP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin OH-57.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRET1_DROER
Sequence: MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQPHRSPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNNNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMGNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIFIWTQVLAALSVSLGSLVVGFVSAYTSPALVSMTDRNITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMNWSMLAFLGAALPVPFLILMFLIPETPRWFVSRGREERARKALSWLRGKEADVEPELKGLMRSQADADRQATQNTMLELLKRNNLKPLSISLGLMFFQQLSGINAVIFYTVQIFKDAGSTIDGNICTIIVGVVNFLATFIGIVLIDRAGRKILLYVSNIAMILTLFVLGGFFYCKAHGPDVSNLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWSCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM
What is the function of this protein?
Low-capacity facilitative transporter for trehalose.  Does not transport maltose, sucrose or lactose.  Mediates the bidirectional transfer of trehalose.  Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph (By similarity).
What are the official names of this protein?
Facilitated trehalose transporter Tret1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_SACEN
Sequence: MPPKSRAGAVKKVRRKEKKNVAHGQAHIKSTFNNTIVSITDPTGAVISWASAGHVGFKGSRKSTPFAAQMAAENAARKAAEHGMKKVDVFVKGPGSGRETAIRSLQAAGLEVGTIQDVTPQPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: XGPT_ALISL
Sequence: MANKFVITWDNMQMYTRQLAEQLLPAEQWKGILAVSRGGLVPAAILARELNIRYVDTVCISSYDHDHQRDMTVVKAMEGDGEGFIIIDDLVDSGDTAVKLRQMYPKGKLVTVCAKPAGIDLVDAYVVDIPQDTWIEQPWDMAVTYVDPICKK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLYA_SULIY
Sequence: MSFPKELEKVLEITKAQNVWRRTQTLNLIASENVMSPLAESVYMSDFMSRYAEGKPYKRYYQGTKYTDEIETLAMDLMNEITNSKDCDLRPTSGTIANAAVFRVLAEPGDKALIAPVQAGAHVSHTKFGTLGALGIQHIEMPFDEENINVDVDKAIKMIEEVKPKFVVLGGSLYLFPHPTKELAPHVHAVGAKLVYDAAHVYGLIEGKVWSSPLKEGADIMTVSTHKTFPGPQGGAIFSDGSEVFKQVSRTIFPWFVSNHHLHRLPATAVTAIEMKYFGESYANQITRNSKALAEALAERGFKVIGENLGYTKSHQVAVDVRQFGGGNKIAKLLEDANIIVNKNLLPYDKPENVSDPSGLRIGVQEMTRYGMKESEMEEIAELFKKVIIDKKDINEVKKEVIDMRKNFLEVKYTFDDMKDLEKYSSKSLKLII
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H31_PICST
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLCAIHAKRVTIQKKDIQLARRLRGERS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.1/H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ASSY_CHESB
Sequence: MATHKDVKKVVLAYSGGLDTSIILKWLQTELGAEVVTFTADLGQGEELEPARRKAEMLGIKEIHIEDLREEFVRDFVFPMFRANALYEGTYLLGTSIARPLIAKRLVEIAAETGADAIAHGATGKGNDQVRFELTAYALNPDIKVIAPWRDWTFKSRTDLLNFARDHQIPVPSDKQGEAPFSVDANLLHSSSEGKVLEDPWSEPPEYVHQRTVSPFDAPDRATEITIGFKRGDAVSLNGEAVSPATLLAKLNDLGRDNGIGRIDLVENRFVGMKSRGVYETPGGTILLAAHRAIESITLDRGAAHLKDELMPRYAELIYNGFWYSPEREMLQALIDKSQEDVEGEVRLKLYKGNVIVTGRRSDKSLYSDALVTFEDDRGAYDQKDAAGFIRLNALRLRTLAARKRLQG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PERF_HUMAN
Sequence: MAARLLLLGILLLLLPLPVPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFPVDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARDAARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREALRRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVPQMLLGEPPGNRSGAVW
What is the function of this protein?
Pore-forming protein that plays a key role in granzyme-mediated programmed cell death, and in defense against virus-infected or neoplastic cells (PubMed:9058810, PubMed:9164947, PubMed:20889983, PubMed:21037563).  Plays an important role in killing other cells that are recognized as non-self by the immune system, e. g.  in transplant rejection or some forms of autoimmune disease (PubMed:9058810).  Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores.  Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes (PubMed:20889983, PubMed:21037563).  Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes (PubMed:20038786, PubMed:20225066, PubMed:32299851).  Perforin pores allow the release of mature caspase-7 (CASP7) into the extracellular milieu (By similarity).
What are the official names of this protein?
Perforin-1, P1, Cytolysin, Lymphocyte pore-forming protein, PFP.
What is the protein family that this protein belongs to?
Belongs to the complement C6/C7/C8/C9 family.
What are the subcellular locations of this protein?
Cytolytic granule. Secreted. Cell membrane; Multi-pass membrane protein. Endosome lumen. Note=Stored in cytolytic granules of cytolytic T-lymphocytes and secreted into the cleft between T- lymphocyte and target cell (PubMed:20038786). Inserts into the cell membrane of target cells and forms pores (PubMed:20889983). Membrane insertion and pore formation requires a major conformation change (PubMed:20889983). May be taken up via endocytosis involving clathrin- coated vesicles and accumulate in a first time in large early endosomes (PubMed:20038786).
Protein: COX17_CANLF
Sequence: MPGLAAASPAPSDSQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALGFKI
What is the function of this protein?
Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
What are the official names of this protein?
Cytochrome c oxidase copper chaperone.
What is the protein family that this protein belongs to?
Belongs to the COX17 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Cytoplasm.
Protein: ATPL_GEOSM
Sequence: MEFFTMCVLAAGIGMALGTLGTGIGQGLAVKSAVEGTSRNPGASGKILTTMMIGLAMIESLAIYALVVCLIILFANPYKDIALELAKSVAK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLPB_PASMU
Sequence: MNFDVVIIGGGLAGLTCGIALQTQGKQCVIINNGQAAIDFSSGSLDLLGQLPSGRQIQHFEQNYTALYQQAAQHPYALVGKDKVIEKARQFEQLAQTLNLGLVGTCDKNHFRVTPLGGLRPTWLSPNSVPIVTNEEMFPHRKIAVLGIEGYHDFQPQLLAENLVQHAQFAHCEVTTGYLNIPELDHLRHQSREFRSVNIAQLLEHKLAFSDLVREIREAVNGASAVFLPACFGLETQEFFSALKQATQLELFELPTLPPSLLGMRQHKQLTQHFKQLGGLMMNGDKVIAADVHHQRVTQVYTQLHQEIPIQAKDVVLASGSFFSKGLVAEFEKIREPIFALDLVENDRFNLQDRMTWTHSRFSAPQPYQQTGVVIDEHCRARKSGQFFENLYAIGNIVGGFNGIELGCGSGVAIVTALVAAEQIGGEK
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: LEP_BUCAP
Sequence: MRNILTIFLLTSTFFTGILWIIDHILLIKNYFYNKKKTKNNNTILINKVILENKKCFFRSLSSLFPTFFIVFIIRSFIYEPFQIPSGSMMPTLLIGDFILVKKFSYGIKEPITNKTIIKMNLPQRGDIVVFKHPKNNIDYIKRVVGLPGDKIQYDINRKKIKICINYTNQKNCENKLFITYSKPKLSNFFQKIYLLKSRTNEEEKVYNSIYFKKVEEKINNLKHNILILDGINSKINDYYQQKGMPKLIWIVPKNKYFMMGDNRDNSLDSRYWGFVPEENLLGKATKIWMSFEKKENEWPTGIRIKRIGNIY
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMA_DESHY
Sequence: MENAANYTRRILKGGAKAHKSLGQNFLMDDRVIEAIAAASIKDPEIPVVEIGPGLGVLTRVLAQKAQKVWAVELDRGKVNLLQRELQGLPVDILNMDALKLDLKDIWGTGKGVLVGNLPYYITSPLLMHFLEQKDSLASMVVMVQKEVADRLVAKPGGKDYGILSIAAQVSAQGEKLFEVPPQAFWPAPKVTSAVVRFELRSYPGFRVKEKDFFRVVKAAFSQRRKTLGNSLAGGLGLPKQQIGEILAAAGVDEQRRAETLSIDEFQAVTEAVMKNLD
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RP132_RABPU
Sequence: MKKNTDSEMDQRLGYKFLVPDPKAGVFYRPLHFQYVSYSNFILHRLHEILTVKRPLLSFKNNTERIMIEISNVKVTPPDYSPIIASIKGKSYDALATFTVNIFKEVMTKEGISITKISSYEGKDSHLIKIPLLIGYGNKNPLDTAKYLVPNVIGGVFINKQSVEKVGINLVEKITTWPKFRVVKPNSFTFSFSSVSPPNVLPTRYRHYKISLDISQLEASNISSTKTFITVNIVLLSQYLSRVSLEFIRRSLSYDMPPEVVYLVNAIIDSAKRITESITDFNIDTYINDLVEAEHIKQKSQLTINEFKYEMLHNFLPHMNYTPDQLKGFYMISLLRKFLYCIYHTSRYPDRDSMVCHRILTYGKYFETLAHDELENYIGNIRNDIMNNHKNRGTYAVNIHVLTTPGLNHAFSSLLSGKFKKSDGSYRTHPHYSWMQNISIPRSVGFYPDQVKISKMFSVRKYHPSQYLYFCSSDVPERGPQVGLVSQLSVLSSITNILTSEYLDLEKKICEYIRSYYKDDISYFETGFPITIENALVASLNPNMICDFVTDFRRRKRMGFFGNLEVGITLVRDHMNEIRINIGAGRLVRPFLVVDNGELMMDVCPELESRLDDMTFSDIQKEFPHVIEMVDIEQFTFSNVCESVQKFRMMSKDERKQYDLCDFPAEFRDGYVASSLVGINHNSGPRAILGCAQAKQAISCLSSDIRNKIDNGIHLMYPERPIVISKALETSKIAANCFGQHVTIALMSYKGINQEDGIIIKKQFIQRGGLDIVTAKKHQVEIPLENFNNKERDRSNAYSKLESNGLVRLNAFLESGDAIARNISSRTLEDDFARDNQISFDVSEKYTDMYKSRVERVQVELTDKVKVRVLTMKERRPILGDKFTTRTSQKGTVAYIADETELPYDENGITPDVIINSTSIFSRKTISMLIEVILTAAYSAKPYNNKGENRPVCFPSSNETSIDTYMQFAKQCYEHSNPKLSDEELSDKIFCEKILYDPETDKPYASKVFFGPIYYLRLRHLTQDKATVRCRGKKTKLIRQANEGRKRGGGIKFGEMERDCLIAHGAANTITEVLKDSEEDYQDVYVCENCGDIAAQIKGINTCLRCSKLNLSPLLTKIDTTHVSKVFLTQMNARGVKVKLDFERRPPSFYKPLDKVDLKPSFLV
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of D6 and A7, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase 132 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: ISPT2_NOSS1
Sequence: MNFPPIHPSTPKMTPPDLDPQKIPQHIAVIMDGNGRWATSRGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFERLLRRELSQMHREGVRISFIGDLTALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAVNEGIVEQHLYTTDTQPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDREAFHQALLSYQKRDRRFGQVKALISA
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase 2.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: ALG10_NEUCR
Sequence: MMDALRVLLETSTFNEVLRGLAISILLAKLTQSTTSSSKSQGSTFITASGFILIYFFARSWLALVNHYAPEPYLDEVFHIPQAQTYCEGRYHEWDNKITTPPGLYLLSVGWHKLVRLVECTPSSLRSNNLVATLLIALIALSCRRRIEAQTAVGIEKSAVSFYAYHTAINIALFPVIFFFSGLYYTDVASTLVMLVAYWNHLNRVASHSEKPGFLNGLWTVVLGVAALFMRQTNVFWVVVYMGGLEAAHVVKGLKPKPVSKNDTPDFVLENIRDSFGFWLRRYAVGDVHDPPVDMAWPDDWALCLLSIGIAALCNPLRVLRQVWPHITIMGLFAGFVAWNGGVVLGDKSNHIATIHLPQMLYIWPFFAFFSAPLLIPRVLSTLADLITHARTPTPSHTTTKDPGRSSWRFTKPSITSKKSSTTKPPQRSGPTPASSSSSSSSFSPDTNSSGRGFRFILDLVLSRKLYYPFYLLATILLSAAIIHYNTIIHPFTLADNRHYMFYIFRYTILRSSLVRLALVAAYTLSRWLIWKRLEGNNPPLRDLAGETGLKITKNKLGWRDEFSASPFVTQDFYGPKTIKTDEQKNIKDKQKEVEEEEEEEEKEDWLIGGAYTTLSLSSTQPSPATSSPPTSTVLLWLLTTTLSLVTAPLVEPRYFILPWVFYRLLVPAMPVSSSLVSSSSSSSFASSTTESGNGDGNDAATAARQQQNGNGKRGLLWNIIRRTDAALALETVWFLAINIGTMYMFLFKPFYWKTASGEMLDGGRLQRFMW
What is the function of this protein?
Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase alg-10, Alpha-2-glucosyltransferase alg-10, Asparagine-linked glycosylation protein 10, Dolichyl-phosphoglucose-dependent glucosyltransferase alg-10.
What is the protein family that this protein belongs to?
Belongs to the ALG10 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TFB1M_HUMAN
Sequence: MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNFLLDLRLTDKIVRKAGNLTNAYVYEVGPGPGGITRSILNADVAELLVVEKDTRFIPGLQMLSDAAPGKLRIVHGDVLTFKVEKAFSESLKRPWEDDPPNVHIIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLSVMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRRKYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISHFKSLCDVYRKMCDEDPQLFAYNFREELKRRKSKNEEKEEDDAENYRL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop.  Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM.  Stimulates transcription independently of the methyltransferase activity.
What are the official names of this protein?
Dimethyladenosine transferase 1, mitochondrial, Mitochondrial 12S rRNA dimethylase 1, Mitochondrial transcription factor B1, h-mtTFB, h-mtTFB1, hTFB1M, mtTFB1, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GLGB1_XANOR
Sequence: MMSGVMTAVSNRWDPGVIRALAEARHGDAFAVLGAHRTDTGRVLRTYLPGAERVSAVLDDGQTIALEAGPEPGLFAGDLPAQGGYRLRIGWPGGEQDTADPYAFGPQLSDFDLHLISEGHHLQLADALGANVVEVDGVRGTRFAVWAPNASRVAVVGDFNSWDARRHPMRLRHQSGVWELFVPDVGPGAHYKYQLRGPHGHELPAKADPVARRAELAPGTASIVADPTPYQWSDDGWMATRARRQAHDAPMSVYEMHAGSWLREEGVDLDWDGLADHLIPYVADMGFTHVELMPVTEHPFGGSWGYQPLGLFAPTARFGTPDGFARFVDRCHREGIGVIVDWVPAHFPTDAHGLAHFDGTALYEHADPREGFHRDWNTLIYNHGRREVSGFLIASAMEFLQRYHVDGLRVDAVASMLYRDYSRNAGEWVPNIHGGRENYETIAFLRRLNALVREHTPGAVMIAEESTAFPGVTADVAHGGLGFHYKWNMGWMHDTLHYASLDPIYRRYHHGELTFSMVYAYSERFVLPISHDEVVHGKGSLLGRMPGDDWQRFANLRAYLGFMFTHPGRKLLFMGCEFGQPTEWNHDSGLPWHLLDDPRHRGVQTLVRDVNRLYVQYPALHAHDDDPSGFAWVVGDDAGNSVVAFLRKGKRGDAPVLVVINFTPVVQHGYRIGVPQGGQWREVFNSDAGIYGGANLGNGGIVTAEQQSMHGHAHALPLLLPPLGAIVLTPPG
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB 1, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 1, Alpha-(1->4)-glucan branching enzyme 1, Glycogen branching enzyme 1, BE 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: YIDD_THEVB
Sequence: MGNGLSKALIVLIRIYQRWISPLFLPTCRYTPSCSAYAVEAIARYGAVKGTYLAIRRILRCHPFAVGGYDPVPTTCPDPCNESSPPNPPC
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RBL6_ARATH
Sequence: MRSRDMERGRKHRGDTQWTAWLTPTIVVANVSIFIVVMYTNDCPKTTTGANGDCVAKLLRRFSFQPLRENPFLGPSSSTLEKLGALDWKKVVQGNEKWRLITAMWLHAGIIHLVMNMFDVIIFGIRLEQQFGFIRIGLIYLISGFGGSILSALFLQKSISVGASGALLGLMGAMLSELLTNWTIYKSKLCALLSFLFIIAINLAIGLLPWVDNFAHIGGLLTGFCLGFILLMQPQSGWEEFRNSSQYGARARSKYNPCQYVLFFVAAVLVVAGLTVGLVMLFDGENGNKHCKWCHRLDCYPTSKWSC
What is the function of this protein?
Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.  Might be involved in response to abiotic stimuli.
What are the official names of this protein?
RHOMBOID-like protein 6, mitochondrial, AtRBL6.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein. Note=Might be neither mitochondrial nor chloroplastic.
Protein: DGP12_ARATH
Sequence: MLFRSCVGMVSRYSRALLPTITISSRIATIVLPFALTRGRKIHTMSKDEEWWKKIRKSPPVDELMLESVVEVFTDSTKYSKVKPWQTLNQESYGGSGFAIAGKKILTNAHVVEGMNDHIFVHVKRHGSQVKYKAKVQKIAHECDLAILEIDSDEFWKGMNPLEFGDIPPLNEIVYVVGYPKAGETICVTKGVVTGVKTGNYLRSSTKLLTIHIDATTYGGNSGGPVITGDKVLGVLFQILGDKKSTGVVIPTPIIRHFITGAEESSHNAVFGSLVLSCQSMKNAQIRNHFKMSPETTGILINKINSSSGAHKILRKDDIILAIDGVPVLSEMRRISFNHFISMKKPDENILVKVLRKGKEHEYNISLKPVKPHIQVQQYYNLPSYYIFGGFVFVPLTKSYIDDKYYKITDEQHVIISQVMPDDINKGYSNFKDLQVEKVNGVKVKNLKHLRELIEGCFSKDLRLDLENDKVMVLNYESAKKATFEILERHNIKSAWASE
What is the function of this protein?
Putative serine protease.
What are the official names of this protein?
Putative protease Do-like 12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RNH_RHOPA
Sequence: MSEADQKPVIIHTDGACSGNPGPGGWGAILKFGDVEKELKGGEPHTTNNRMELLAAISALEALTRPCSVDLYTDSQYVKNGIGSWIHNWKRNGWKTADKKPVKNVDLWQRLDAALKTHSIRWHWVKGHAGHAENERADQLARDGLTENRMKSRVK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.