PharMolix/UniProtQA huggingface dataset:
Protein: RS6_LACLM
Sequence: MTKYEILYIIRPNIDEEAKTALVERFDAILTENGAANLESKDWEKRKLAYEINDFREGIYHIATFEAETTSEALSEFDRLAKINLDILRHMIVKVEA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: SYS_PROMA
Sequence: MLDQRKIRENPTLIEKGLARRGLKVNLAPLTEASERLKGLEQHRNSLQAKGNLIGKEVGQKIKSGISPNSEEVVSLRSKGNELKREINVLEEEEKALAKSIRKRILNYPNIPYSECPDGKDENDNLQIRNWGNPLKGEGYKEHWEIAEELGLLDTEKSVRIAKSRFVTLFNHGARLERSLINFMLDIHTSKGYSEVLPPVLVNTASLEGSGQLPKFAEESFKCSEDDLWLTPTAEVPLTSLHRNEVIPFEKLPIKYVAYSPCFRREAGSYGRDTRGLIRLHQFNKVELYWFVEPKKSKEAHQIITADAEAILQKLELPYRVVELCSGDLGFSASCTYDLEVWLPGANSYREISSCSNCDDFQARRSFIRTKKGNQTQLVHTLNASGLAIGRTMAAILENGQQSDGTVKLPKALVPYFGENQLTPQ
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRR1_YEASV
Sequence: MVSTHNRDKPWDTDDIDKWKIEEFKEEDNASGQPFAEESSFMTLFPKYRESYLKTIWNDVTRALDKHNIACVLDLVEGSMTVKTTRKTYDPAIILKARDLIKLLARSVPFPQAVKILQDDMACDVIKIGNFVTNKERFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMKNIHPIYHIKELMIKRELAKRPELANEDWSRFLPMFKKRNVARKKPKKIRNVEKKVYTPFPPAQLPRKVDLEIESGEYFLSKREKQMKKLNEQKEKQMEREIERQEERAKDFIAPEEEAYKPNQN
What is the function of this protein?
Required for 40S ribosome biogenesis.  Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.  Essential for vegetative growth (By similarity).
What are the official names of this protein?
KRR1 small subunit processome component, KRR-R motif-containing protein 1, Ribosomal RNA assembly protein KRR1.
What is the protein family that this protein belongs to?
Belongs to the KRR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PERC_DROME
Sequence: MSRILFILLLLIVTQLSELQAAAFSVRQNRFDEVPDLQTPAPLATSTESSKKPEKATSGLLKKCLPCSDGIRCVPQIQCPAHVRMESHEKPQICDLPAGKFGYCCETGQNHTAPKPETSPKERRSGFPTILSPAVLDEARRNFEHLMHGVAQIPVRRGFPDFAHGLVFHSTAKDDLHNFAISNSAIEQVMTTQLFGKKEQVPVEDFITNNVPIKFTETPLAHHCQPPPVCGNIRSVYRSMDGTCNNPEPQRSLWGAAGQPMERMLPPAYEDGIWTPRAHSSDGTPLLGARKISRTLLSDVDRPHPKYNLMVMQFGQVLAHDISQTSSIRLEDGSLVQCCSPEGKVALSPQQSHFACMPIHVEPDDEFFSAFGVRCLNFVRLSLVPSPDCQLSYGKQLTKVTHFVDASPVYGSSDEASRSLRAFRGGRLRMMNDFGRDLLPLTNDKKACPSEEAGKSCFHSGDGRTNQIISLITLQILLAREHNRVAGALHELNPSASDETLFQEARRIVIAEMQHITYNEFLPIIIGPQQMKRFRLVPLHQGYSHDYNVNVNPAITNEFSGAAYRMGHSSVDGKFQIRQEHGRIDEVVNIPDVMFNPSRMRKREFYDDMLRTLYSQPMQQVDSSISQGLSRFLFRGDNPFGLDLAAINIQRGRDQGLRSYNDYLELMGAPKLHSFEQFPIEIAQKLSRVYRTPDDIDLWVGGLLEKAVEGGVVGVTFAEIIADQFARFKQGDRYYYEYDNGINPGAFNPLQLQEIRKVTLARLLCDNSDRLTLQAVPLAAFVRADHPGNQMIGCDDPNLPSVNLEAWRA
What is the function of this protein?
Required for ovarian follicle maturation.  Involved in the formation of a rigid and insoluble egg chorion by catalyzing chorion protein cross-linking through dityrosine formation and phenol oxidase-catalyzed chorion melanization.
What are the official names of this protein?
Chorion peroxidase, Peroxinectin-related protein, Dpxt.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. XPO subfamily.
What are the subcellular locations of this protein?
Secreted. Note=In the chorion layer of the mature eggs.
Protein: PSBN_TOBAC
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Photosystem biogenesis factor 1, Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RECR_SHEDO
Sequence: MKFSPLVDELIQALKGLPGVGPKSAQRMAFNLLERDRKVGLKLAESLKNAMTDVGHCQSCRTFTEQSLCPICASHKRGASGVICVVETPADVLAIEAGGHFNGRYFVLLGHLSPLDGVGPEELGLSLLEQHLQTLDVTELILATNPTVEGDATAHFIADMARRHKVIISRIAHGVPVGGELEYVDSTTLALSFNGRIAL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TTLL3_MOUSE
Sequence: MQGVSSALLLSAGQLGPGAAWYRQEGSSECSWLRRSQPSELRTNFSSRWPWPRNSESRRSERLQWPGPASAKPEVASCGDSRRDYSSLPARHLSSARESSMPGALGTVNPQPVRTLVPPTLDEPLPDALRPPDDSLLLWRGLTKGPNHMGRLRNAKIHVERAVKQKKIFMIHGRYPVIRCLLRQRGWVEKKMVHPPGTALPAPQKDLDSSMLGDSDATEDEDEEENEMFRESQLLDLDGFLEFDDLDGIHALMSRMVRNETPYLIWTTRRDVLDCRFLSKDQMINHYARAGSFTTKVGLCLNLRNLPWFDEADADSFFPRCYRLGAEDDKKAFIEDFWLTAARNVLKLVVKLEEKSQSISIQAREEEAPEDTQPKKQEKKLVTVSSDFVDEALSACQEHLSSIAHKDIDKDPNSPLYLSPDDWSQFLQRYYQIVHEGAELRYLEVQVQRCEDILQQLQNVVPQLDMEGDRNIWIVKPGAKSRGRGIMCMNRLDEMLKLVDCNPMLMKDGKWIVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSVHLCNNSIQRHLEASCHRHPMLPPDNMWSSQRFQAHLQEVDAPKAWSSVIVPGMKAAVIHALQTSQDNVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVIDRRLDRSCDTGAFELIYKQPAVEVPQYVGIRLLVEGSTIKKPVPVGHRRTGVRSSLPHLLTQQGSGESKDSGSPTHRSASRKNARAESLEHTEKPEPAAVASVSGKGKKAPFHFPSLHSKAWLPSPRVHRPQGRVLRLQHDQLVGSKALSTTGKALMTLPTAKVLMSFPPHPDLKLAPSMLKPGKVGFELCCTTWRVVLSGGIGEEGHRQRAAPRPSSAPGKGLSSTEPCSKTET
What is the function of this protein?
Monoglycylase which modifies alpha- and beta-tubulin, adding a single glycine on the gamma-carboxyl groups of specific glutamate residues to generate monoglycine side chains within the C-terminal tail of tubulin (PubMed:19524510).  Not involved in elongation step of the polyglycylation reaction (PubMed:19524510).  Preferentially glycylates a beta-tail peptide over the alpha-tail, although shifts its preference toward alpha-tail as beta-tail glutamylation increases (By similarity).  Competes with polyglutamylases for modification site on beta-tubulin substrate, thereby creating an anticorrelation between glycylation and glutamylation reactions (PubMed:33414192).  Together with TTLL8, mediates microtubule glycylation of primary and motile cilia, which is essential for their stability and maintenance (PubMed:23897886, PubMed:25180231).  Involved in microtubule glycylation of primary cilia in colon which controls cell proliferation of epithelial cells and plays an essential role in colon cancer development (PubMed:25180231).  Together with TTLL8, glycylates sperm flagella which regulates axonemal dynein motor activity, thereby controlling flagellar beat, directional sperm swimming and male fertility (PubMed:33414192).
What are the official names of this protein?
Tubulin monoglycylase TTLL3, Tubulin--tyrosine ligase-like protein 3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: PKS1_METGA
Sequence: MNHVTIKQSDTRADPFRVFIFGDQSSCNLSNLQLLLFKKSNVYLASFIDQVNLTLRHEIARLTAAERQSFPAFSSIQNLVARALKKDTSVALESTLATIYHLCCFLNYFGDGQEAYPTGPTTHVSGLCIGALAAAAVSSSKSLAELVQAGIDAVRVSLKVGLLVARTAALFSHQESNGASSSPWSYAVPDSQLPLALAEEAIESYQAKTNIPPLSLPYISAKGQNSWTVSGPPAIVQHFLQTSQFEKTLRLTPLAVHAPYHAPHIFSAVDVQHIMHAVGTVSNFSSKLSFISSSSSRNLPTGLKFQDLLYRAVEDILILPLDLREAAENIRLVLEATDNVQQCALFPISTGVCPSLKQSFSPAMASRVSIVDCIMERATADAGPKSTSGPKPSESKIAIIGMSGRFPESADVEAFWDLLHQGLDVHRPVPPDRYNGELYYDVTGKRKNTCKVMHGCWINDPGLFDAKFFNISPKEAEQSDPGQRLALATAYEALEAAGVVADRTPSTQRDRVGVFYGMTSDDYREVSCGQNVDTYFIPGGNRAFTPGKINYFFKYCGPSVSVDTACSSSLAAIHLACNSIWRNECDTAIAGGTNVMSNPDSFVGLDRGYFLSRTGNCHTFDDEADGYCRADAVGTVILKRLEDAIADHDPILGVISGALTNHSADAVSITRPHSGAQEEIFSKLLTESGVHPHQVSYIEMHGTGTQAGDATEMTSVLNCFAPSTSPRRLPHESLHLGSTKANVGHSESASGVSALIKVLLMMEKNIIPPHCGIKGKINHKFPTDLDQRNVHIAKTATQWNRRNEFNNIRRAFVNNFSAAGGNTALLVEDYPLLIADSSQQDARTAHVVTVSAKCIKSLKGNLENLKKFVQKQASTDGFLPKLSYTTTARRMHHPFRVAIPAANSEQLLSALDEELKHDSYTCSSESPVAFVFSGQGSQYSAMGQHLLHFTIFRDEVHAYDILAQRHGFPSIMPLIDGSVDIEDLEPLVVQLGTVCVQMALASLWMALGMRPAYVVGHSLGHYAALKVAGVLTASDTIYLVAMRARLLQNKCSRGSHAMLAIRSSAAAIQAHLDEGIHDIACINGPQDTVVSGCIDDIDRLSQKLMDKGIKATRVNVPFAFHSAQVDPILDELEAIASQVEFHTPRVAIGCPLLGRTFKAGETPSIEANHIRRHCRETVNFFDVLRSAKDEGFVSEKTAWIEIGPHTVCSNLVKANINQDIVAVPSLMRNKDGWQVLASSVATLYRHGSSVAWDEYHHDFEACKEVLRLPAYSWDNKLYWIDYVHDWLLTRGDPPVQAAASLPAPPSSFSTASVHRIVHESVDKGKLTLTAECEFTNEQLREVVYGHVVNGNRVCSSSLYTDFGVTLGSYILEKYRPDLQDHAVDVQDMVVNKALVHKEGPTMLLRIDVVLDMTDSKAASMSIYSVNSKGNKTADHAQSSLHFEQPKVWLKSWDSTQYYVERSIEWLKEKADQGLNSRMSSGVIYKLFSSLVDYSTAYKGMQEAIVNTEDFEATALVRFQVDEGNFRCNPMWVDSCGQLAGFLMNGHAKTPKDQVFINHGWQSFRTVRKFSKDKTYRTYVRMRCIEGTTYAGDVYIFDDEGIVGVCGSITFQGIPRKVLNTAMPPPKSQNEAPVRSAPAKPAAKPPKSASSEHSGHFARHSNIEPLKLDAALKSATTARNPMLAVFKIVSEEIGIPSASVDNGLVFADYGVDSLLSLSISGRLREELDLDVESSAFETCATLADLATHLGLDTFSSDQSSGQSSSSGGLSPRSDSIGEITSSATTPPSLSPRGSVSGSQCKDVCAILAEEIGVSMSEITNDTDLGALGMDSLMSLAVLSRLREELELDLEGDFFVSHPNFSSFKHMFQQGHGDEVEPEPSAELKQYRATSTLLQGNPKSALYTLFLLPDGSGSSFSYAPINAVRKDVCVFGLNCPWLKSAEKLVQFGLKGLATLYVEEIRRRAPHGPYNLGGWSAGGICAYEAAIQFTREGETVERLILLDSPNPIGLEKLPARLFDFVNGLGLFGDGKAPDWLLAHFLAFIDALDEWKPVPWDKALGGNSPPPRTYILWAEDGICKGTDARPEYRDDDPREMKWLLENRTNFGGNNWDVLLGQQSLSIERIQDANHFTMLRKGKNSERVAAFIRSTFG
What is the function of this protein?
Polyketide synthase; part of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress (PubMed:29958281).  The polyketide synthase Pks1 produces 1-acetyl-2,4,6,8-tetrahydroxy-9,10-anthraquinone though condensation of acetyl-CoA with malonyl-CoA (By similarity).  The dehydratase EthD and the laccase Mlac1 further convert the anthraquinone derivative into the final conidial pigment (By similarity).
What are the official names of this protein?
Polyketide synthase 1, Conidial pigment biosynthesis polyketide synthase.
Protein: IF5A1_MEDSA
Sequence: MSDEEHQFESKADAGASKTYPQQAGTIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFTSKKLEEVYVPSSHNCDVPHVNRTDYQLIDISEDGFVSLLTENGNTKDDLKLPTDDSLLTQIKDGFAEGKDLVVSVMSAMGEEQICALKDIGGKN
What is the function of this protein?
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-1, eIF-5A-1, eIF-4D.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
Protein: BIGR_XYLFT
Sequence: MVNEMRDNTVPHMTREDMEKRANEVANLLKTLSHPVRLMLVCTLVEGEFSVGELEQQIGIGQPTLSQQLGVLRESGIVETRRNIKQIFYRLTEAKAAQLVNALYTIFCTQEKQA
What is the function of this protein?
Represses an operon that probably comprises itself, PD_1892, PD_1893, PD_1894 and blh.  Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon (By similarity).
What are the official names of this protein?
Biofilm growth-associated repressor.
Protein: FGF13_RAT
Sequence: MAAAIASSLIRQKRQAREREKSNACKCVSSPSKGKTSCDKNKLNVFSRVKLFGSKKRRRRRPEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSEHFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSHNEST
What is the function of this protein?
Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity).  Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity).  Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity).  Regulates voltage-gated sodium channels transport and function (By similarity).  May also play a role in MAPK signaling (By similarity).  Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity).
What are the official names of this protein?
Fibroblast growth factor 13, FGF-13.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Cell projection, filopodium. Cell projection, growth cone. Cell projection, dendrite. Cell membrane, sarcolemma. Cytoplasm. Nucleus. Note=Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes.
Protein: TSP3_HUMAN
Sequence: METQELRGALALLLLCFFTSASQDLQVIDLLTVGESRQMVAVAEKIRTALLTAGDIYLLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGRTHTVLLRLRGPSRPSPALHLYVDCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRMQGFVESMKIILGGSMARVGALSECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGTDTDIDGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVPEDFEPFRRQLLQGRV
What is the function of this protein?
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions.  Can bind to fibrinogen, fibronectin, laminin and type V collagen.
What are the official names of this protein?
Thrombospondin-3.
What is the protein family that this protein belongs to?
Belongs to the thrombospondin family.
Protein: ARSI_RAT
Sequence: MHALSGFSLVSLLSLGYLSWDWAKPGLVADGPAEAEDQPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHSPQKPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHARHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLASFPGSWWNLERMASIRQAVWLFNISADPYEREDLADQRPDVVRTLLARLADYNRTAIPVRYPAANPRAHPDFNGGAWGPWASDEDEEEEDEEEEGRARSFPRGRRKKKCKICKLRSFFRKLNTRLMSHRI
What is the function of this protein?
Displays arylsulfatase activity at neutral pH, when co-expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts.
What are the official names of this protein?
Arylsulfatase I, ASI.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum. Note=Localized in the intracellular granular structures.
Protein: IF1_WIGBR
Sequence: MTKEENIEMQGIVLDTLPNTMFKVELENKHVVLAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIIFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS29_IXOSC
Sequence: MGHENIWYSHPRKYGPGSRYCRVCANHHGLIRKYGLNICRRCFRQYAADIGFKKLD
What are the official names of this protein?
40S ribosomal protein S29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: BIP3_ORYSJ
Sequence: MARGATWTRRLHLHGLFLAVLLLLTLPAGSTAAAGGGGGTVIGIDLGTTYSCVGVYRNGHVEIIANDQGNRITPSWVAFTGGGERLIGEAAKNQAAANPGRTVYDAKRLIGRRFADAEVQRDMRLLPFAVVDKGGKPHVRVEVRGGDVRLLSPEEVSAMVLARMKETAEAYLGEEVTRAVVTVPAYFNDAQRQATKDAATIAGLAVERILNEPTAAALAYGVGKEGAGGKNVLVFDLGGGTFDVSVLAIDGGVYEVLATNGDTHLGGEDFDQRVMEHFVELVRRKHGRDIAGDARALGKLRRECERAKRALSIQHQVRVEVESLFDGVDLSEPLSRARFEELNNDLFRKTMAPVRKAMADARLSNADIDEIVLVGGSTRIPKVRQLLRDYFGGKQPNQGVNPDEAVAYGAAIQANIVGGDTDNKTRDMVVLDVTPLTLGLETAGGVMATLIPRNTPVPTKRAQLFSTYKDKQTTVTVKVFEGERSMTRDNRLLGRFDLAGIAPAPRGAPQIEVAFEVDADGILSVSAADRATGRSERITISGDDRKTSREEIDRMLGEAEEFADEDRRHRERAGARNSLEAYVYGVKNAVVGGEMAGAMDGGEKEKVEAAVMEAYEWLDGNQDVGKEEYEEKLRELEDVCNPVMSAVYQRSGGSRRDGDGGGDDDHDEL
What is the function of this protein?
Functions as chaperone during endoplasmic reticulum (ER) stress response.
What are the official names of this protein?
Heat shock 70 kDa protein BIP3, Luminal-binding protein 3, OsBiP3.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: SOL3_ALTSO
Sequence: MGGMLGFFVRQLTFMPKPLPQNVRLDGKTAIVTGANVGLGLEASKEMASHGLARVILGVRTVSKGEAAKQEILKQSPNCDVQVWPVDHESFESMVAFGERAQSLDRLDIVILCAGVKNLVFSLSKTGHEQNVQVNHLGTSLLSLLLLKPLKDTAAKTGSPSRLTIVASEVHFWTPFDERKAPSILARLDEKDSFRGMERYNTSKLLNILWMRELSSRVTGNVVINAVNPGLCASALHRTDPTPGLAYLNKIFAWTPAQGGHNLTYAATQHVDEPGAYLSEQHLEK
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of the phytotoxin solanapyrone, a causal agent of early blight disease of potato and tomato (PubMed:20486243).  The prosolanapyrone synthase sol1 is a polyketide synthase that produces the octaketide desmethylprosolanapyrone I via sequential condensations of 7 malonyl-CoA units with one acetyl-CoA unit, and one methylation step (PubMed:20486243).  The octaketide backbone is further methylated by the sol2 O-methyltransferase to yield prosolanapyrone I (PubMed:20486243).  Prosolanapyrone I is hydroxylated to prosolanapyrone II by the cytochrome P450 monooxygenase sol6 (PubMed:20486243).  The solanapyrone synthase sol5 then catalyzes the oxidation of prosolanapyrone II and the subsequent Diels Alder cycloisomerization of the product prosolanapyrone III to solanapyrones A and D (PubMed:9659400, PubMed:18256508).  Solanapyrones A and D are then converted into solanapyrones B and E, respectively, by the sol3 dehydrogenase (PubMed:20486243).
What are the official names of this protein?
Short chain dehydrogenase sol3, Solanapyrone biosynthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RDRP_BPMS2
Sequence: MSKTTKKFNSLCIDLPRDLSLEIYQSIASVATGSGDPHSDDFTAIAYLRDELLTKHPTLGSGNDEATRRTLAIAKLREANGDRGQINREGFLHDKSLSWDPDVLQTSIRSLIGNLLSGYRSSLFGQCTFSNGAPMGHKLQDAAPYKKFAEQATVTPRALRAALLVRDQCAPWIRHAVRYNESYEFRLVVGNGVFTVPKNNKIDRAACKEPDMNMYLQKGVGAFIRRRLKSVGIDLNDQSINQRLAQQGSVDGSLATIDLSSASDSISDRLVWSFLPPELYSYLDRIRSHYGIVDGETIRWELFSTMGNGFTFELESMIFWAIVKATQIHFGNAGTIGIYGDDIICPSEIAPRVLEALAYYGFKPNLRKTFVSGLFRESCGAHFYRGVDVKPFYIKKPVDNLFALMLILNRLRGWGVVGGMSDPRLYKVWVRLSSQVPSMFFGGTDLAADYYVVSPPTAVSVYTKTPYGRLLADTRTSGFRLARIARERKFFSEKHDSGRYIAWFHTGGEITDSMKSAGVRVIRTSEWLTPVPTFPQECGPASSPR
What is the function of this protein?
This is the catalytic subunit of the viral RNA-dependent RNA polymerase complex.  This complex is involved in viral RNA replication that produces (+)-stranded genomes via a complementary, (-)-stranded intermediate.
What are the official names of this protein?
RNA-directed RNA polymerase beta chain, RNA replicase beta chain.
Protein: Y06B_BPT4
Sequence: MSLSKEQKDTLFSLIHEVMDKNSELEKVCNECGPFSANEYEELSKEFDNKEQELIDYINSL
What are the official names of this protein?
Uncharacterized 7.1 kDa protein in tk-vs intergenic region.
Protein: DRL20_ARATH
Sequence: MGISFSIPFDPCVNKVSQWLDMKVSYTHNLEKNLAALEKTMKELKAKRDDLERRLKREEARGLQRLSEFQVWLDSVATVEDIIITLLRDRNVEIQRLCLCRFCSKSLTRSYRYGKSVFLRLREVEKLKGEVFGVITEQASTSAFEERPLQPTIVGQDTMLDKAGKHLMEDGVGIMGMYGMGGVGKTTLLTQLYNMFNKDKCGFDIGIWVVVSQEFHVEKVQDEIAQKLGLGGDEWTQKDKSQKGICLYNILREKSFVLFLDDIWEKVDLAEIGVPDPRTKKGRKLAFTTRSQEVCARMGVEHPMEVQCLEENVAFDLFQKKVGQTTLGSDPGIPQLARIVAKKCCGLPLALNVIGETMSCKRTIQEWRHAIHVLNSYAAEFIGMEDKVLPLLKYSYDNLKGEQVKSSLLYCALYPEDAKILKEDLIEHWICEEIIDGSEGIEKAEDKGYEIIGCLVRASLLMEWDDGDGRRAVCMHDVVREMALWIASELGIQKEAFIVRAGVGVREIPKIKNWNVVRRMSLMENKIHHLVGSYECMELTTLLLGKREYGSIRSQLKTISSEFFNCMPKLAVLDLSHNKSLFELPEEISNLVSLKYLNLLYTEISHLPKGIQELKKIIHLNLEYTRKLESITGISSLHNLKVLKLFRSRLPWDLNTVKELETLEHLEILTTTIDPRAKQFLSSHRLLSHSRLLEIYGSSVSSLNRHLESLSVSTDKLREFQIKSCSISEIKMGGICNFLSLVDVNIFNCEGLRELTFLIFAPKIRSLSVWHAKDLEDIINEEKACEGEESGILPFPELNFLTLHDLPKLKKIYWRPLPFLCLEEINIRECPNLRKLPLDSTSGKQGENGCIIRNKDSRWFEGVKWADEATKKRFLPSCQLISLK
What is the function of this protein?
Probable disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein At1g63360.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: SYL_CHRSD
Sequence: MDAQYTPHAIESAAQTFWDKNQCFKAVEDATREKFYCLSMFPYPSGKLHMGHVRNYTIGDVVSRFQRMQGKNVLQPMGWDAFGMPAENAAIKNRVPPGAWTYDNIDAMRRQLKALGFAYDWNREFATCDVDYYRWEQWFFTKLVEKGLVYKKMSTVNWDPVDQTVLANEQVIEGRGWRSGALVERKEIPLWFLKITDYADELLADLDKVDWPEQVKTMQRNWIGKSTGVELSFAVADSSEQLEVYTTRPDTLYGVTYVAVAAGHPLARQAAQDNPALGDFLEECQQGGNSEAELATMEKKGMDTGHKAIHPLTGREVPIFVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGIPIEPVIADAEGNTPDLSQGAHTEHGKLINSGEFDGLEFDAAFDAIAARLEANGQGTVKTNFRLRDWGVARQRYWGAPIPVKYGPEGQTVPLTDDELPVALPMEVEVDASGSPLKKMPAFYDLGEGWTRETDTFDTFMESSWYYARFASADNMEAMLDERADYWLPVDLYIGGIEHAILHLLYARFFHKLMRDFGLVASDEPFQRLLTQGMVIAETFYRANDDGSKDWFNPADVDVQRDDKGRPVSAILREDGQPVEMGGIEKMSKSKNNGVDPQAMIDRFGADTVRLFMMFAAPPEQSLEWSDSGVEGAHRFLKRLWKLVADHLDAGTPAALDADALNDDQKTLRRKTHETIAKASDDIGRRTTFNTAIAAVMELVNAIGRFEDTSPQGLAVTREALEACVLVLAPIVPHACHALWDALGHDTPVIDAAWPQADEAAMVKDSVELAVQVNGKLRARLDVPAAADKAAIEAQALEAENVRRHTEGKTIRKVIVVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ING4_HUMAN
Sequence: MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK
What is the function of this protein?
Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4 (PubMed:16387653).  Through chromatin acetylation it may function in DNA replication (PubMed:16387653).  May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation (PubMed:15251430, PubMed:15528276).  Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA (PubMed:15029197).  May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC (PubMed:15029197).  Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1) (PubMed:15897452).  Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).
What are the official names of this protein?
Inhibitor of growth protein 4, p29ING4.
What is the protein family that this protein belongs to?
Belongs to the ING family.