PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_YERPP
Sequence: MSETFIYPQANLIAGVDEVGRGPLVGAVVTAAVILDPNRPIVGLADSKKLSEKRRLSLYDEITEKALSWSLGRAEPEEIDQLNILHATMLAMQRAVSGLHIVPDYVLIDGNRCPKLQMPSLAVVKGDSRVAEISAASILAKVTRDREMTELDLLFPEYGFAQHKGYPTAFHLEKLAALGATVHHRRSFGPVKRVLGLV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNS3_RAT
Sequence: MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSSRYQERKEESHEKDWDQKSNDVSTDSSFEESSLFEKELEKFDELRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCVHSMSEFQNEDGEVDDPVLEGVEIACIAWFTGELAIRLVAAPSQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDELASSLTSIPICWWWATISMTTVGYGDTHPVTLAGKIIASTCIICGILVVALPITIIFNKFSKYYQKQKDMDVDQCSEDPPEKCHELPYFNIRDVYAQQVHAFITSLSSIGIVVSDPDSTDASSVEDNEDAYNTASLENCTAK
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself.  Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (By similarity).  Heterotetrameric channel activity formed with KCNB1 show increased current amplitude with the threshold for action potential activation shifted towards more negative values in hypoxic-treated pulmonary artery smooth muscle cells (PubMed:9362476).
What are the official names of this protein?
Potassium voltage-gated channel subfamily S member 3, Delayed-rectifier K(+) channel alpha subunit 3, Voltage-gated potassium channel subunit Kv9.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.
Protein: PARA_TRYBB
Sequence: MAPRSLYLLAILLFSANLFAGVGFAAAADESASNVIVKGGKGKEREDGPEEPEETGPEETGPEETGPEETGPEETGPEETGPEETEPEPEPGAATLKSVALPFAVAAAALVAAF
What is the function of this protein?
Major surface antigen of procyclic forms.
What are the official names of this protein?
Procyclic form-specific polypeptide A-alpha, PARP A-alpha, Procyclin A-alpha.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: DADA_SHIB3
Sequence: MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIVVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKFRFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMVVRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQLLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: AMYA_DROYA
Sequence: MFLAKSIVCLALLAVANAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGFAGVQVSPVNENAVKDSRPWWERYQPISYKLETRSGNEQQFASMVKRCNAVGVRTYVDVVFNHMAADGGTYGTGGSTASPSTKSFPGVPYSSLDFNPTCSINNYNDANQVRNCELVGLRDLNQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMWPADLAVIYGRLKTLNTDHGFNSGSKAYIVEEVIDMGGEAISKSEYTGLGAVTEFRHSDSIGKVFRGKDQLQYLTNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFSDTDQGPPTTDGHNIASPVFNSDNSCSGGWVCEHRWRQIYNMVAFRNAVGSDAIQNWWDNGSNQIAFSRGSRGFVAFNNDNYDLNSSLQTGLPAGTYCDVISGSKSGSSCTGKTVSVGSDGRASIYLGSSEDDGVLAIHVNAKL
What are the official names of this protein?
Alpha-amylase A, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: SYH_CLOPS
Sequence: MAIQAQKGTKDMLPNDAYKWHYIEEKLRKISAEYGIREIRTPMFEATELFKRGVGETTDVVQKEMYTFEDKGGRSITLKPEGTAPAVRAFIENSLYADAQPTKMFYFTPCFRYEKMQKGRLREFHQYGIEVFGSQEASIDAEILSLVMRALTEDFGIKGLSLNINSLGCPKCRAKFNEALKQYLKENYDNLCETCKTRFEKNPMRIIDCKEKRCKEIVKEAPSILDYICEECSDHFSKLKAYLDVMGIEYNIDPQIVRGLDYYSKTVFEVIKDGLTVCGGGRYDYLVEEVDGPKTPAMGFGLGLERLLLILDEEGIEIPEPVRCEVYIGSMGDRAKLEAMKLAFNLRKSGIKAEIDHLGKSVKAQMKYANKIGAKYTFVIGDSEIEENKIKIKRMSDGEQFEVSLDINEIVNIVK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1707_PELTS
Sequence: MADARKLLGRMGEEAAARYLEKKGCRILSRNHCCRLGELDLVVSDGDVLVFVEVRARTGEEYGLAQESITGRKKSRLRLLAWQYLKEKGKTGSMCRFDVIAVLFDREGRVKRLEHFENAF
What are the official names of this protein?
UPF0102 protein PTH_1707.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: EFG2_PSEAE
Sequence: MARTTPIELYRNIGIVAHVDAGKTTTTERILFYTGVNHKMGEVHDGAATMDWMVQEQERGITITSAATTAFWQGSTKQFPHRYRFNIIDTPGHVDFTIEVERSLRVLDGAVVVFSGADGVEPQSETVWRQANKYHVPRLAYVNKMDRQGADFLRVVAQIKQRLGHVPVPIQLAIGSEENFSGQIDLVKMKAIYWNDADQGTSYREEEIPAELRALAEEWRAHMVEAAAEANDELMNKYLEGEELSIEEIKAGLRQRTLANQIVPAVLGSSFKNKGVPLVLDAVIDYLPAPSEIPAIRGTDPDDEEKHDERHADDDEPFSALAFKIATDPFVGTLTFARVYSGVLTSGDAVLNSVKGKKERVGRMVQMHANQRDEIKEVRAGDIAALIGMKDVTTGDTLCAIDKPIILERMDFPDPVISVAVEPKTKADQEKMGIALSKLAQEDPSFRVKTDEETAQTIISGMGELHLDIIVDRMRREFGVEANIGKPQVAYRETIRNTCEIEGKFVRQSGGRGQFGHCWIRFAPADEGQEGLEFHNEVVGGVIPREFIPAIQKGIEDQMQNGVLAGYPLIGLKATVYDGSYHDVDSSEMAFKIAASMATKQLSQKGGAVLLEPVMKVEVVTPEDYMGDVMGDLNRRRGLIQGMEDTPAGKVIRAEVPLGEMFGYATDVRSMSQGRASYSMEFVRYAEVPASVAEGIVARQGR
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_STACT
Sequence: MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPVDNSGENKVTIDEELALKWLKDGAKPTDTVHNILSREGILKTFDEQRHSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ACCA_YERPY
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINLDEEVQRLREKSVELTRKIFSDLGAWQIAQLARHPRRPYTLDYIANIFTDFEELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPIVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGITAHRLKELKMIDSVIPEPLGGAHRDYAAIAISLKAQLLADLNDLDVLNDEELLNRRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA11_ARATH
Sequence: MSTVGELACSYAVMILEDEGIAITADKIATLVKAAGVSIESYWPMLFAKMAEKRNVTDLIMNVGAGGGGGAPVAAAAPAAGGGAAAAPAAEEKKKDEPAEESDGDLGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P1-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: H7A01_CYRHA
Sequence: MKSQIFFAVAALFLLTVRTYASKSKEQDLRDALFSAMFSADNQLNPQERECRYWLGTCSKTGDCCSHLSCSPKHGWCVWDWTFRK
What is the function of this protein?
Ion channel impairing toxin that inhibits voltage-gated sodium channels.  The recombinantly expressed toxin shows a weak activity against Nav1. 7/SCN9A, and shifts the voltage dependence of channel activation to more depolarized potentials.
What are the official names of this protein?
U5-theraphotoxin-Hhn1a, U5-TRTX-Hhn1a, Hainantoxin-VII, HNTX-VII, Peptide F4-32.71.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 18 (Hntx-VII) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31B_ECODH
Sequence: MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: F16PA_NITVU
Sequence: MSQELTLQQRMDGEAGSDPLRQAVKEAVAALARAAVDISDLTCRGALAGITGQAQGRNTDGDIQKDLDVRADQIIRDALGKLPIAALASEEMADLDILNPAAPICVAFDPLDGSSNINTNMSVGTIFSIMPTPSDVNAAFRQAGSAQLAAGFVVYGPQTSLVLTLGRGVDIFTLDRADRVFKLTGSSVQIPTDANEFAINASNRRHWDLPVRAYIDECLAGADGPCGKNFNMRWIGSLVAEAFRILIRGGIFLYPGDARDGYEEGRLVVYEAHPMAFIVEQAGGGASTGRKRVLDIVPDSLHQRVPLIMGSIKNVQRLEHMHTVPDVALEANAPLFGNRGLFRV
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPCL1_HUMAN
Sequence: MGKQNSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF
What is the function of this protein?
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
What are the official names of this protein?
Hippocalcin-like protein 1, Calcium-binding protein BDR-1, HLP2, Visinin-like protein 3, VILIP-3.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
Protein: CCMN_SYNY3
Sequence: MQLPPVHSVSLSEYFVSGNVIIHETAVIAPGVILEAAPDCQITIEAGVCIGLGSVISAHAGDVKIQEQTAIAPGCLVIGPVTIGATACLGSRSTVFQQDIDAQVLIPPGSLLMNRVADVQTVGASSPTTDSVTEKKSPSTANPIAPIPSPWDNEPPAKGTDSPSDQAKESIARQSRPSTAEAAEQISSNRSPGESTPTAPTVVTTAPLVSEEVQEKPPVVGQVYINQLLLTLFPERRYFSS
What is the function of this protein?
Beta-carboxysome assembly initiates when soluble RuBisCO is condensed into a liquid matrix in a pre-carboxysome by the RbcS-like domains of probably both forms of CcmM.  CcmN interacts with the N-terminus of full-length CcmM, and then recruits the CcmK major shell protein via CcmN's encapsulation peptide.  Shell formation requires CcmK proteins and CcmO.  CcmL caps the otherwise elongated carboxysome.  Once fully encapsulated carboxysomes are formed, they migrate within the cell probably via interactions with the cytoskeleton.
What are the official names of this protein?
Carboxysome assembly protein CcmN, Carbon dioxide concentrating mechanism protein CcmN.
What is the protein family that this protein belongs to?
Belongs to the CcmN family.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes.
Protein: KUP_XANP2
Sequence: MALSFSRDRTRPLPFAAEIGALGVVFGDIGTSPLYALKQGVLAVGGTNFLGGDVLGLLSLITWSIILSVTVKYVMLVLRADNDGEGGILALVTLLDLHRSALGMRWYLLAAGLLGAAMLIGDGVLTPAMSVLSAIEGLQVISPELEHWVVTLTVLVLLAVFLSQRLGTERIASFFGPIMLMWFGSLGALGVYGILQAPQVLAGLDPRYGIMLMVNHPGLAGVILGACFLAVTGGEALYADLGHFGRPVIARAWLFVAMPALLLNYFGQGAILLVDPNAVRNPFYDLCPDVFDIPLLFLATAATVIASQSIITGVFSLAKQAIELGYLPPMRIRYTSEHNEQHIYVGRLNWLLMIACIAVVLGFEASDRLASAYGIAVAFAMVTTSILFIAQVHRSWGWPAPAVWAMATGLLTIDFAFASANMTKIHDGGWLPLSIAAAIIFVMVSWRRGLEGVVAQQVRFTEPLDSFVARKDRVNDVEAPRTAIFLSRAGAMTPVALSRMADLLKVRFEKAVIVSVWIAARPRVSVEDRVKVTTLNEGFVRVDLRFGYMQQIDVPSVLGPALSARGIDPDAAIYVIGHERIIPPDEVTKIKDVVAHVFAFLARNAERSVDRFGLPRARTVEIGYPVKL
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PR7A2_RAT
Sequence: MQLSFSRPRPWTLLLMVVSNLLLWENVSSGNLNSNETDGDLLLHRGLFDTATRLSQDIRDLDIEFLRMYAVNEVSEKLYNKHMLEFIEDMDFVVKALTCCHNYSIKTPENLDEAQQIPFNDFPWLILSRMWGWNETSKNLLTILRSIPGMHDDVISLAQAIERKLAELFEYTQSILTLIFGPTENVDRSIFSGLEDLKASDEELRFFALCKFSYCLRVDLQTIELYFKLLQCAVNVNSNVCLSINSEDSS
What are the official names of this protein?
Prolactin-7A2, Placental prolactin-like protein F, PLP-F, PRL-like protein F.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSC2_RAT
Sequence: MRLSLCLLTILVVCCYEANGQTLAGQVCQALQDVTITFLLNPEEELKRELEEFDAPPEAVEANLKVKRCINKIMYGDRLSMGTSLVFIMLKCDVKVWLQINFPRGRWFSEIN
What is the function of this protein?
Part of prostatein which is the major secretory glycoprotein of ventral prostate gland.
What are the official names of this protein?
Prostatic steroid-binding protein C2, Prostatein peptide C2.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family. Lipophilin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS19_CAMJE
Sequence: MARSLKKGPFVDDHVMKKVIAAKKANDNKPIKTWSRRSTITPDMIGLTFNVHNGKSFIPVYITENHIGYKLGEFAPTRTFKGHKGSVQKKIGK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL19_COPPD
Sequence: MDIIRRIEQTMMREDVPPVEVGDTVRVKWRFTERDRSGEDKSRVQAYEGIVIAKKGTGISESIVVRKISSGVGVEKTFPLHSPNLVDLEVVTRGKVRRAKLYYLREKKHLVVKKKSRF
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: COXZ_RHILO
Sequence: MSKKPAGKNSNRIVAAVCLAFFTGMIGMAYAAVPLYKMFCQATGYGGTTQRVEKQYAGRVLDREITVRFDANIAGVPWEFQPVQRSMTMKIGETVQAHYQATNKFDRPVTGRATFNVQPELAGPYFNKVECFCFTDTSLKPGETVDMPVLFYVDPDIVNVPELKDVKTITLSYTMFPVEKNKPVASSEPVQGTSKIISDTEANLGG
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein CtaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RRF_MYCS2
Sequence: MIDETLFDAEEKMEKAVSVARDELGSIRTGRANPGMFNRINIDYYGSMTPITQLASINVPEARLVVIKPYEASQLRAIEDAIRNSDLGVNPSNDGNIIRVAIPQLTEERRRELVKQAKSKGEDAKVSVRNIRRKAMEELSRIKKDGEAGEDEVSRAEKDLDKSTHTYTAQIDELVKHKESELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMCO2_MACFA
Sequence: MALTPTNLNNEMSLPMKMDCQEQELTEKNNSFFQKLNVTKSVMQDLLKEIIKVDYILDRSDDEDDISSENPQTDFLHKGMLELEAKHDQDLGKQDEQETDVDEYPQASTSLQFSKKNLLEFLLKDMLTLKGQIDKLEDRGLDLDQGTNTEVNARNEVYELKKKVMESLEDLCKNVELLSAKLRMYQMEGENTDSHSSEETDMEEMETLLPQAPASFLVQNSPPPNTVWKCALRIFIMFYVLTVTGLLCYILFFGATFLFERVLLRMLGCRTTWDLREMIEPFLNSEVEALLPS
What are the official names of this protein?
Single-pass membrane and coiled-coil domain-containing protein 2.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SPXH_STAAB
Sequence: MAGELRIMENKSREDINLSPVSKIEIYSFFDPFSSDCFKLSAILSKLRIEYNQYIRIRHILNPSLKVLTKCQAQSTSNFDNIALAYKAAELQGRVRAERFIHLMQNEIIPKRDIITESMICDCIQNAGIDLEVFKDDLQKSKLTESLKIDLHIAREMEIEQAPSLVFFSEDVHEEGLKVEGLYPYHIYTYIINELMGKPIEKNLPPKLETYIQQQQLVTMEELLTIYEWPEKLLNKELKKLAIQQKIEKLKYPDGDFWKSKMPKIKSK
What is the function of this protein?
Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions.  Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
What are the official names of this protein?
ClpXP adapter protein SpxH.
What is the protein family that this protein belongs to?
Belongs to the SpxH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T178A_HUMAN
Sequence: MEPRALVTALSLGLSLCSLGLLVTAIFTDHWYETDPRRHKESCERSRAGADPPDQKNRLMPLSHLPLRDSPPLGRRLLPGGPGRADPESWRSLLGLGGLDAECGRPLFATYSGLWRKCYFLGIDRDIDTLILKGIAQRCTAIKYHFSQPIRLRNIPFNLTKTIQQDEWHLLHLRRITAGFLGMAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV
What is the function of this protein?
Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1.
What are the official names of this protein?
Transmembrane protein 178A.
What is the protein family that this protein belongs to?
Belongs to the TMEM178 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NOT5_YEAST
Sequence: MSQRKLQQDIDKLLKKVKEGIEDFDDIYEKFQSTDPSNSSHREKLESDLKREIKKLQKHRDQIKTWLSKEDVKDKQSVLMTNRRLIENGMERFKSVEKLMKTKQFSKEALTNPDIIKDPKELKKRDQVLFIHDCLDELQKQLEQYEAQENEEQTERHEFHIANLENILKKLQNNEMDPEPVEEFQDDIKYYVENNDDPDFIEYDTIYEDMGCEIQPSSSNNEAPKEGNNQTSLSSIRSSKKQERSPKKKAPQRDVSISDRATTPIAPGVESASQSISSTPTPVSTDTPLHTVKDDSIKFDNSTLGTPTTHVSMKKKESENDSEQQLNFPPDRTDEIRKTIQHDVETNAAFQNPLFNDELKYWLDSKRYLMQPLQEMSPKMVSQLESSLLNCPDSLDADSPCLYTKPLSLPHPTSIFFPNEPIRFVYPYDVPLNLTNNENDTDNKFGKDSKAKSKKDDDIYSRTSLARIFMKFDLDTLFFIFYHYQGSYEQFLAARELFKNRNWLFNKVDRCWYYKEIEKLPPGMGKSEEESWRYFDYKKSWLARRCGNDFVYNEEDFEKL
What is the function of this protein?
Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.  The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes.  Preferentially affects TC-type TATA element-dependent transcription.  Could directly or indirectly inhibit component(s) of the general transcription machinery.
What are the official names of this protein?
General negative regulator of transcription subunit 5.
What is the protein family that this protein belongs to?
Belongs to the CNOT2/3/5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NUOH_BACC2
Sequence: MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRFGLLQTVADVLKLLLKEDSIPKAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVGLLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMISYEIPLVMSVIGIVLLAGSLNLNEIVAAQEKVWYIFVQPIGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWAFFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPRIRGDQLMEFGWKVLLPIALANIFLTALIKELFF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DXR_AGRFC
Sequence: MTNASEMPRKLTILGSTGSIGTNTLDVVRQLGGRDGFEIMALTGAGNIALLAEQAREFGAQLAVTADDDKYEALKSALAGTGIKVAAGMAGLEEAASMDAGWVMAAIAGTPGLAPTLTAARRGADIALANKECLVSAGDVFLRTVKQGGGRLIPVDSEHSAIFQCLTGEYKQAVERIVLTASGGPFRTWSRDEMSNVTADIARAHPNWSMGLKVSIGSASMFNKGLEMIEAKYLFDLRPDQVDVIVHPQSIIHSMVGYTDGSYIAQLGSPDMRTAISYALTYPERGNLSVERLDFAKLARLDFEAPDEARFPALRLARMALERGGLQGAALNAAEETAFHAFVAGGIGFLDMAEIVETVMDRMHDGRTAETMDDVFSADEEARRHALELIATKEKAA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ENDAL_METKA
Sequence: MAAKGELVGSKVLVRNDRDANRLYSSMYGKPSRRGLQLWPEEALFLCEIGRLEVRSGNVRISPEELMDRFVEEDPRFPVRYAVYADLRRRGWKPKPGRKFGTEFRAFRGEDERIAVKVLQEELDEFTAQDILEWLKLVEGTEFELVVAIVDNDYDLNYYVFSELVL
What are the official names of this protein?
EndA-like protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
Protein: C340_ORYLA
Sequence: MGNFLYFSAETWTLLVAFITLLLVYAYWPYGTFKRLGIPGPKPVPFFGTMLAYRKGFFNFDDECRKKYGKTWGIYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFRLNGPLYDAVSIAEDDQWKRIRSVLSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEMKEYFGPYSMDVVTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVAFFPFLGPILEKFEFSLFPSSVMDFFFAALRKIKANHENNKQKSRIDFLQLMIDSQKNNQNGLQDKGLSDHEILSQAMIFIFAGYETTSSSLTFLAYNLATNPEVMKKLQKEIDATFPNKAPVQYVPLMEMEYLDCVVNESLRLYPIAARLERVAKATVEVNGLVIPKDMVVMVPTWPLHRDPELWPEPEKFKPERFSKENKDTFDPYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSVCKETEVPFEMDVQGFLAPKRPIQLKLTPRSASSS
What are the official names of this protein?
Cytochrome P450 3A40.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: DCUP_SYNP2
Sequence: MSESNNTPLLLRAARGEKVERTPVWMMRQAGRYMKIYRDLREKYPSFRERSENPDLAIEISLQPWHAFQPDGVIMFSDILTPLPGMGIPFDIIESKGPIIENPIRTQAQVDAMTPFDPAESLPFIKTILGTLRQEVGNASTVLGFVGAPWTLAAYAIEGKSSKNYAIIKNMAFSEPAVLHSFLGKIADAIADYVCYQIECGAQVIQMFDSWAGQLSPQDYDMFALPYQKRVVDKVKAKYPDFPLILYISGSAGVLERMGKSGVDIVSVDWTVDMADARQRLGKDMKVQGNIDPGVLFGSQDFIKARIIDTVRKAGNWGHILNLGHGVLVGTPEDNVRFFFETCKNVQSFL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.