PharMolix/UniProtQA huggingface dataset:
Protein: LYSM3_XENTR
Sequence: MSGRIPNHGYMQPASISATSCGHDYQFPTLANSESDLLEEDAEEFELRPRGKEKTRRSTSKERIDDIVYISRDICEGDTLNSIALQYCCTVADLKRANNFLNEQDFFALRTIKIPVKRFSVLTQPHFSPKAKATRPGTLQLSPEHQESDLLIGPSSYETAGSFLQEVDRDIEKIVKSTDTKKESLNEVVSALSQEHFEPEQILVPQRDPYHGADWSLGWWTAVAIMVFVGIITPLFYFLYYEVLMKVNTSHTLNSIEKSGPS
What is the function of this protein?
Essential for Golgi structural integrity.
What are the official names of this protein?
LysM and putative peptidoglycan-binding domain-containing protein 3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Golgi apparatus.
Protein: WDR12_ANOGA
Sequence: MSLHITSATEGQLQVHFTTKQKQYAVPDVPYSIRANVGCSELNTLLGTVLKDAGNKQGAKVAFDFLLNGEFVRSTLSQHLKERDISFEDTIELEYVERYPAPQPQDCLLHDDWVSAVQAKDGWILTGTYDNTVNLWNTKGKHKLTIPGHVAAVKGVAWISLNEQTGVFASASHDQTIMIWEWNMTTNTAECVHVCKGHERGVGCIAVNPAKTQMASGSMDTMLKIWSTELQADKGEPSATKKAKLEQDNVRTPVVTLAGHREFVSGVQWIDNTTIATCSWDHTIKLWDLSMGGIKTEFTGNKSFFDLSYSPLNGMIITASPDKNLRLYDPRSKHGNFVKNTYLGHSQWVQTCRWSTTNEYLFVSGAYDNRVKLWDYRSPKAPIFELIGHEDKVLACDWSNPKYILSGGSDNAVRVFKSRIAVDNTKDD
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: YQGF_LACCB
Sequence: MRLMGLDVGSRTVGVAVSDPLGWTAQGLEIIRINEDKEQFGIARLKELVKQYEVTAFVLGLPKNMNNSIGPRAEKSQAYGELLKTTFGLPVDFIDERLTTVEASRMLIEEADASRKRQKQVIDKLAAQMILQNYLDAKGPLTKQ
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR653_MIMIV
Sequence: MDSYEPSQLIWARLLLYEISKRNGETEYQHTNGPVWWGPNDNKTVYLSITDCSGFVNALLRKSFELSQKDMVEWFDSQRPLAVDYYNTIYHQNGFTRIKNIYKLEPGDFIAIKFPNHHPSLDDTGHIMMINSYPEIMASKNLPDEYQNYNNILQFRVNVIDQTATPHGRYDTRYSPDDNQNGLGSGYIKLYTNIDGTIIGYSWSLSKKSRYIDKTVHPIVVGRLDIY
What are the official names of this protein?
Uncharacterized protein R653.
What are the subcellular locations of this protein?
Virion.
Protein: DARA_BPP1
Sequence: MEQFNINKGMTIKPGLDVLPPPVTDDEYRALMAGEDRYLMTESNTLEEIEATFFYDTPIHWCATDLLEAISSTRLQLHRTMQAFVRALNQKLNGTGISAGSDKTGDVAQSGARAIGGAEIGRARNVNGLPVLPAIIPLSDGQTISILFHSPTAENRITNSDTLVAFQFLLNKKDVTHTVAPMSGRDMTLAQVTMKLANLAEKNSAKFQRAQKKKKALVDEITQLQADSDQKEDAMSDLADQVAAVEGQKADLEQKINAVASEADSLYEENERLQGEIDRLNRTGGRDTIAPAGMTGGHSRALTDRLASIKNRMHMDGEATLSNGASMKQFIGDGEGYIQLTDPDGSVYMIKAKSIQGVDMADAIGKLFKAYKAGNVSEYLVQPEEHKPENVEPESAEDTGSSSPEPEVSVGAYRYALQMRPAAPGAIPEGNKAILPRPDEGDPYYEYARYGIATYDTPLSDQQMSEYDLKLLPREDSFDFLAKTLTNGPFGKYAQKALELATNSPDEFRVMLKTQFQKTFPNIAFPGGAGTEKMVQSMINALQAEVGEITQPEPAPAQPDETVSEADAEANKAIEYLNNVMDMQSTDMAEIRNARGNVREAIAALQTAGRFEENEELVNGAARHLADLLVAIQKAGVAA
What is the function of this protein?
Internal capsid protein that is probably ejected along with the viral DNA and prevents degradation of viral DNA by the host type I restriction-modification antiviral defense system (PubMed:3029954).  Plays a role in directing proper capsid assembly (PubMed:28509398).
What are the official names of this protein?
Defense against restriction protein A, DarA.
What are the subcellular locations of this protein?
Virion. Note=Internal capsid protein. A proteolytically cleaved 60 kDa form is incorporated into the virion.
Protein: PDXJ_GEOUR
Sequence: MAKLGVNIDHVATIRQARGGVEPDPVAAAAIAELAGADGITIHLREDRRHIQDRDLKLLRQTVKTRLNLEMAATDEMVNIAISVKPDMCTLVPEKRQELTTEGGLDVRLNLESIKEAVQRLQDGGLIVSLFIDPDPDQIKAADKTGADYIEIHTGAFAEARDWKSEQAELAKIENAIKLAGKLGMGINAGHGLNYANIRKVAALGGIEEYNIGHSIISKAVLVGLDRAVRDMVDLVKYA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_SYNP6
Sequence: MSRYRGPRLRIVRRLGDLPGLTRKAARRSYPPGQHGQARRKRSEYAIRLEEKQKLRFNYGLSERQLVRYVKKARRMQGSTGTNLLQLLEMRLDNLVFRLGFAPTIPGARQLVNHGHVTVNGRVVDIASYNCRPGEVIGVRQREASRKLVTANLEYPGLANVPVHLDFDKNKLEAKVTGACEREWVALQINELLVVEYYSRKV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CYPLB_PSYBR
Sequence: GDLPICGETCFGGTCNTPGCVCAWPVCNR
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide psyleio B.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: A291_SSV1
Sequence: MRKSLLALLTLSLALLSFLITPSMALNSGGSPIPIYYNYYNYYSLNAEGFGFSFNNSNNWVETNFISITINLPSSLPNNYQINNAYSIVVGLSPYPVSNINIFNSPLEAYVELFSNPPNTYPNEIGFVVSYGSTVFYSYTTLYSSFAGTQLTITISYTGNGFGVQFSDSNGFSHSVSVSSVNFVPYGALILGSLIPNGNYYYYPVGNMLPNASVNFSYTISSFTIEGNPATSVDITTLGLEGNTAIYTSSSNWFKWVSGSVVITNAVAYTYTDLARIGGSAQINYTASQLY
What is the function of this protein?
Essential for virus function.
What are the official names of this protein?
Uncharacterized protein A-291.
Protein: RECX_STRPM
Sequence: MKITKIEKKKRLYLIELDNDDSLYVTEDTIVRFMLSKDKVLDNDQLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQWIDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQKLFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIEDLLDKELDKQYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCS1_COPJA
Sequence: MSKNLTGVGGSLPVENVQVLAGKELKNLPNRYVRPELEHDDVVPIDNSLEIPVIDLSRLLDQQYACDELAKFHSACLDWGFFQLINHGVREEVIEKMKVDTEDFFRLPFKEKNAYRQLPNGMEGYGQAFVTSEEQKLDWADMHFLITKPVQERNMRFWPTSPTSFRETMEKYSMELQKVAMCLTGMMAKNLGLESEILTKPLRTVFNREDELLPSMSSCGEGLGLSPHSDATGLTLLIQVNEVNGLHIKKDEKWVPIKPILGAFVVNIGDVIEIMSNGIYKSIEHRAVINTDKERLSIAAFHDPEYGTKIGPLPDLVKENGVKYKTIDYEDYLIRSSNIKLDGKSLLDQMKL
What is the function of this protein?
Involved in the biosynthesis of the common precursor of all benzylisoquinoline alkaloids such as morphine, sanguinarine, codeine or berberine.  Condenses dopamine and phenylacetaldehyde, 3,4-dihydrophenylacetaldehyde or 4-hydroxyphenylacetaldehyde.
What are the official names of this protein?
S-norcoclaurine synthase 1, CjNCS1.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: CRGA_MYCUA
Sequence: MPKSKVRKKNDFTVKPVSRTPVKVKVGPSSVWFVALFIGLMLIGLVWLMVFQLAAVGSQAPAALNWMAQLGPWNYAIAFAFMITGLLLTMRWH
What is the function of this protein?
Involved in cell division.
What are the official names of this protein?
Cell division protein CrgA.
What is the protein family that this protein belongs to?
Belongs to the CrgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LYSM1_MOUSE
Sequence: MASPSRQPPLGGSGLLHGSRARSYGSLVQSSCSPVRERRLEHQLEPGDTLAGLALKYGVTMEQIKRTNRLYTNDSIFLKKTLYIPILSEPRDLFNGLDSEEENDGEEEVRPSKDEIGSSSGRRKNRGSGSGRPNGTGLPPHQETSTPSHDLSASDFLKKLDSQISLSKKAAAQKLRKGESGVPEEDTGLYPSSPRMQQRAVLGPVPLTRTSRTQTLRDQEDEIFKL
What are the official names of this protein?
LysM and putative peptidoglycan-binding domain-containing protein 1.
Protein: Y1707_THEVB
Sequence: MMSYSLRVADLPAGDRPREKLLSQGARYLSSAELLAILLGTGQGAGKLSAVGLGQFILKQLGERTGDSTDAVSALRDITPEELMAIPGVGPAKATTILAAVELGKRVFQSRPGEQTIIDSPALAAAVLAADLMWQATERFAVLLLDVRHRLLGSHVITVGTATETLAHPREIFREAVRRNASRLIIAHNHPSGNLSPSQADLDLTKQILQAGQLMEIPVLDHLILGNGDYQSLREITPLWQQVPQGDGSA
What are the official names of this protein?
UPF0758 protein tlr1707.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: HOA1_RHOOB
Sequence: MTKLYIQDVTLRDGMHAVRHRITPDDVGTIVAALDAAGVDAIEVAHGDGLAGGSLNYGPGSNTDWEWIEAAADNLTHATLTTLLLPGIGTIAELEQAHKLGVRSIRIATHCTEADVSAQHIAKARELGMDVSGFLMMSHMTPAENLAEQAKLMESYGAHCVYVTDSGGRLTMNGVRDRVRAYRDILDPGTQIGIHAHENLSLSVANSVVAVEEGVTRVDASLAGHGAGAGNCPIEAFIAVANLHDWQHGSDLFALQDAADDLVRPLQDRPVRVDRETLTLGYAGVYSSFLRHAETASKNYGIDVRTILQEVGKRGLVGGQEDMITDIALDLVASGPVSTY
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: HFLD_VIBVY
Sequence: MANTLYDRTIAFAGMCQAVALVQQIARNGHCDQDAFETSIKAILNTNPANTLDVFGNESQLKLGLECLVKGIDSTPTGSEVTRYLISLMALERKLMGRNDAMSQLGDRIQMVQRQTEHYDLFEEQMISNVASIYLDVISPIGPRIQVTGTPTVLQQTSNQHKVRALLLSGIRSAVLWRQVGGRRRHLIFGRKKMVEQAQILLARM
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLYA_DESRM
Sequence: MFNGKLAQTDPELAKAIELEHQRQQRNIELIASENFVSPAVLEAQGSILTNKYAEGYPGKRYYGGCEFVDIAESLAISRAKKLFGADHANVQPHSGAQANFAVYFALLQPGDKILGMNLAHGGHLTHGSPVNVSGKYFNVVAYGVEEDTGCINYEKLREIALQEKPKMIVAGASAYARAIDFKKIGEIAKEIDAYFFVDMAHIAGLVAAGLHQSPVPYADVVTTTTHKTLRGPRGGMILCKEEYAQLIDKAIFPGSQGGPLMHVIAAKAAAFGEALKPEFKAYQQQIINNAQALAKGLLERGFNLVSGGTDNHLILVDLRGTGITGKQAETLLDEVHITCNKNAIPFDPEKPFVTSGIRLGTPAVTTRGFKEKDMDKVAEIIALTLQEKDNPDTQEKARAMVKELCDKYPLYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_CLOBJ
Sequence: MAGAGLIGIRRRIKSVTNIRKITKAMGLVSTAKLRKARVNLEINKKYYNEYKIILKDIINFIEDSNIYIDGNGSHKKLYVIFTSDSGLCGSFNINIINNVINEIKEDKENSLVIVIGQKGRMYLKKLGINTLAEYIEIPDVPTTKEARTIAKNIIKLYSSKEVGEVFLVYSEFYSPVKQQVLINKILPFTKENKSDNKYIEFNPPVTQLMDEILENYLKATILNCFSNSKASENGSRMTAMNGATDNANDLLDNLDLQFNRLRQSAITQEISEIVGGAEAQR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SFP1_SCHPO
Sequence: MPSLALPINKPSHHNVNYNGNSFNSIHATSFGMSPQSWGNSFSGQAWLRDTIPSLSNVVESQTIPEEDSTSYLNRLEEAFCRDFRCCGQTLEDLHQLIHHYEEQHAVLATDSAVPQEYSLDSNNAAQSNHSHIQALKQRERIRMHDLADQLGTSEISDNSAVLPFAFPANGGAPGPYRVSVVVPAAAAAAAAAASSDMSSDEASSQAETTGTPKKMPESLVMDASSPLSDMSMSIDVGESAANNVFAFNQKDMVDSTYLPPFNYDHDVFSFAPSVASADQFTESSMSPTPEVVSPAATNSAISSPFVRKSSSDLEAKPSKKQRSTPAFSHDSPLTIDYPGSNLVVVDKPYKCPVPNCDKAYKNQNGLKYHKLHGHCSPITTPTPAPIPHQGFVVENKPYRCEVCSKRYKNLNGLKYHRTHSHLQVSMAQAQREVQMNFMRTA
What are the official names of this protein?
Zinc finger protein sfp1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FGF8_CANLF
Sequence: NKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIELENNYTALQNAKYEGWYM
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration.  Required for normal brain, eye, ear and limb development during embryogenesis.  Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.  Plays a role in neurite outgrowth in hippocampal cells (By similarity).
What are the official names of this protein?
Fibroblast growth factor 8, FGF-8, Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: C719A_COPJA
Sequence: MEMNPLLVCATVAIVFATTTIIRILFSSSSLPQMKWPSGPRKLPIIGNLHQLGDDVLHVALAKLAKVHGSVMTIWIGSWRPVIVISDIEKAWEVLVNKSADYGARDMPEITKIASASWHTISTSDAGSFWQNVRKGLQSGAMGPLNVAAQNQYQERDMKRLIKAMSDEAANNNGIVKPLDHIKKNTVRLLTRLIFGQAFDDNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPSHKKAEREAFLVKCRVEELVRPLLSSKPPTNSYLYFLLSQNFEEEVIIFCIFELYLLGVDSTSSTTTWALAYLIREQGAQEKLYQDIRMTLGDVDLVKIEDVNKLKYLQGVVKETMRMKPIAPLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFLEGETGTAYNKAMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVNAFKWSCVEEGKLPDMGEELSFVLLMKTPLEARIAGRNV
What is the function of this protein?
Involved in the last but one step of the biosynthesis of berberine, an antimicrobial benzylisoquinoline alkaloid.  Converts (S)-tetrahydrocolumbamine (THC) to (S)-tetrahydroberberine (THB) also called (S)-canadine.
What are the official names of this protein?
(S)-canadine synthase, (S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming), Cytochrome P450 719A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Protein: SEM6A_HUMAN
Sequence: MRSEALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLDIQMIMIMNGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIKVLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIRINGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTKIAVDTAAGPYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKEGGACSHLSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYESRGGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILAFVMGAVFSGITVYCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDPKPEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTLQQKRKPSRGSREWERNQNLINACTKDMPPMGSPVIPTDLPLRASPSHIPSVVVLPITQQGYQHEYVDQPKMSEVAQMALEDQAATLEYKTIKEHLSSKSPNHGVNLVENLDSLPPKVPQREASLGPPGASLSQTGLSKRLEMHHSSSYGVDYKRSYPTNSLTRSHQATTLKRNNTNSSNSSHLSRNQSFGRGDNPPPAPQRVDSIQVHSSQPSGQAVTVSRQPSLNAYNSLTRSGLKRTPSLKPDVPPKPSFAPLSTSMKPNDACT
What is the function of this protein?
(Microbial infection) Acts as a receptor for P. sordellii toxin TcsL in the in the vascular endothelium.
What are the official names of this protein?
Semaphorin-6A, Semaphorin VIA, Sema VIA, Semaphorin-6A-1, SEMA6A-1.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PRS58_RAT
Sequence: MKLVFCILSTLLGTFAYNPDHIAGTTPPYLVYLKSDYLPCTGVLIHPLWVVTSAHCNLPDLRVILGITNPADTTEHDVEVSDYEKMFRHPYFSVSSISYDLMLIKLRRGIKHSYYAKAVKLPQHTVPVNAMCSVSTWAYNLCDVTKEPDSLQTVNVSVISKAECHNAYKAFDIRENMICVGIVPGRRLPCKEVTAAPAVCNGVLYGILSYADGCVLRADVGIYASIFHYMPWIENIMKNN
What are the official names of this protein?
Putative inactive serine protease 58, Trypsin-X3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUD_PROMH
Sequence: MNKFTQHTGIPVPLDAANVDTDAIIPKQFLQKVTRTGFGKHLFHDWRFLDDEGTQPNPSFILNQPIYQDASILLARENFGCGSSREHAPWALTDYGFHAVIAPSFADIFYGNSFNNQLLPIKLSDEQVTQLFNWVTEHAGTPITVDLVAQQVIAGELCFSFEIDAFRRHCMIEGLDSIGLTLQHQAEISAYEAKQPAFMR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: FFAR3_HUMAN
Sequence: MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
What is the function of this protein?
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity.  In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers.  SCFAs serve as a source of energy but also act as signaling molecules.  That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins.  Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation (PubMed:12711604).  Activated by SCFAs and by beta-hydroxybutyrate, a ketone body produced by the liver upon starvation, it inhibits N-type calcium channels and modulates the activity of sympathetic neurons through a signaling cascade involving the beta and gamma subunits of its coupled G protein, phospholipase C and MAP kinases.  Thereby, it may regulate energy expenditure through the control of the sympathetic nervous system that controls for instance heart rate.  Upon activation by SCFAs accumulating in the intestine, it may also signal to the brain via neural circuits which in turn would regulate intestinal gluconeogenesis.  May also control the production of hormones involved in whole-body energy homeostasis.  May for instance, regulate blood pressure through renin secretion.  May also regulate secretion of the PYY peptide by enteroendocrine cells and control gut motility, intestinal transit rate, and the harvesting of energy from SCFAs produced by gut microbiota.  May also indirectly regulate the production of LEP/Leptin, a hormone acting on the CNS to inhibit food intake, in response to the presence of short-chain fatty acids in the intestine.  Finally, may also play a role in glucose homeostasis.  Besides its role in energy homeostasis, may play a role in intestinal immunity.  May mediate the activation of the inflammatory and immune response by SCFAs in the gut, regulating the rapid production of chemokines and cytokines by intestinal epithelial cells.  Among SCFAs, the fatty acids containing less than 6 carbons, the most potent activators are probably propionate, butyrate and pentanoate while acetate is a poor activator (PubMed:12496283, PubMed:12711604).
What are the official names of this protein?
Free fatty acid receptor 3, G-protein coupled receptor 41.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
Protein: COQ4_ASPTN
Sequence: MSILGRRGAAIVARELPLPASSSSILASHPRAFSIFSRPQPKYPGHVPLNAIERGALAVGSAVGALMNPRRADLIAACGEATATPYFIYRLRDAMLSDPTGRQILRDRPRITSTTLPLPYLRSLPENSVGRTYAAWLDREGVSPDTRDEVKYIDDEECAYVMQRYRECHDFYHAVTGLPIFVEGELALKAFEFLNTLIPMTGLSMFAAVRLKPAERERLFSIYLPWAVRSGLGSKELICVYWEKILEKDVNELRRELGIERPPDMREIRRMIREQKKREKERLKQAE
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein coq4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SODM3_MAIZE
Sequence: MALRTLASKNALSFALGGAARPSAESARGVTTVALPDLSYDFGALEPVISGEIMRLHHQKNHATYVVNYNKALEQIDDVVVKGDDSAVVQLQGAIKFNGGGHVNHSIFWKNLKPISEGGGEPPHGKLGWAIDEDFGSFEALVKRMNAEGAALQGSGWVWLALDKEAKKVSVETTANQDPLVTKGASLVPLLGIDVWEHAYYLQYKNVRPDYLNNIWKVMNWKYAGEVYENVLA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 3.3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MST3_DROHY
Sequence: MLLSRFTSVFPRNVIVRGVSTLTSHVDRNYLVRSSFDKCQRFPFSDSKQEAEDVKKKCEEAAAKKKCAEAAKKEKEAAEKKKCAEAAKKEKEAAEKKKCAEAAKKEQEAAQKKKCAELAKKEKEAAEKKKCAEAAKKEKEAAERKKCEEAAFKQKCEEAAKKKKEAKKAAELQQKCAALAKKEKEAEMMKKCEEAAKKKAAEEAAKKKAEEVAAKKKADEAAAKKKCAEAKKKAEEAALKKMCEEAALKKMCEEAALQKKCAEAAKNAKKTDSET
What is the function of this protein?
Possible structural role in the sperm tail.
What are the official names of this protein?
Axoneme-associated protein mst101(3).
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_PSYCK
Sequence: MLQPKRTKFRKMHKGRNTGLAHRGSTVAFGQIGLKSLTRGRMTARQIEAARRTITRKIKRGGKIWIRVFPDKPITNKPLEVRMGKGKGPVEYWVCEIKPGKILYELEGISEELAREALTLAAAKLPFKTTIVKRTIM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: IMP04_NAUMA
Sequence: TLASAIASAR
What are the official names of this protein?
Uncharacterized protein IMPP4.
Protein: GLPE_ALIF1
Sequence: MDQFQHISVVDAQEKLQQQDLNAVLVDIRDPQSFIRGHVENAFHLTNDTIVELMNEVDFEQPVLVMCYHGHSSQGAAQYLVNQGYEEVYSVDGGFEGWHKAGLPVEK
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MKK4_LEIME
Sequence: MPPKRPQALEKLHVEPHDKGVSITDTMTLVVKGEGGVEMRVKQTGIAQGPGSSSAGGQPKSDAVMNKIKFEDLRIGSELGKGSQGKVRVAQHKLTGEKYAMKYIAFDGDSDDMRSALEAELRQVAAVKHHNVVSSYEAFFRDGRLYIVLEYMDCGTMNNLIDRHPEGFSEDMLAYIARELFKGLEFLHHLNMIHRDIKPANVLANTKGEIKISDFGVAKTLSGGDLQTLSAQGSVPYMSPERIQSKPYSFNSDIWSAGLTIAECAFREYPFASLKPKLFELCQAIASGTAKINWDDRETKFSDEFKEFIELCLRPEATRPSATEMLSHSLIQKASNVNPLEAGRWMSRKK
What is the function of this protein?
Protein kinase which regulates promastigote proliferation in host macrophages, thereby playing an essential role in parasite virulence.
What are the official names of this protein?
Putative mitogen-activated protein kinase kinase 4, LmxPK4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, cilium, flagellum. Nucleus.