PharMolix/UniProtQA huggingface dataset:
Protein: SYI_METMP
Sequence: MKQVKSVNFRELDKKVKEYWKKENTYKKVKALNEHGPEYYFVDGPPYCSGAIHLGTAWNKIIKDTVLRFKRIQGYNVLDKAGWDMHGLPIEVKVENEFNIGSKKDIETKIGTQEFINKCKEFALNHLGHMQGQFENLGVWLDFENAYMPIKRDYMEMGWWTLKKAHEKELLTKDLRSGYWCPRCETSLAEHEVRGEYKEVLDPSVYVKFKLEKSDEYITIWTTTPWTLPSNMLVCVNPEFDYAYVNVEFENGTAETWIIAEKLVNDVMKKAEKNNDISKFSISKVVKGDSLIGLKYIHPLLEENEKQQEFAKIENVHTIVPGDHVTLEGGTGLVHTAPGFGEDDFNIGKEHNIPVYAPIDDNGKYTDSIWKGTFVKDMDESVIETLISKNLLVNSGKVKHTYPHCWRCKTPLLFRATEQWFLSISKIKDSIIEQGKTVDWVPDWVKTRYVNGVSFVGDWNISRQRYWGIPLPIWICEECGNYEVIGSVDELKERANEKDVDLSDIHKPAVDKITLTCSCGGKMKRTPDVLDVWYDSGLAPYASIGSKKLKKAQFITEGNDQVTKWFYSQHALSAVVFDDTSYEKCMMHGFTLDETGEKMSKSLGNIVSPDDVTEQYGADVLRFYLLSANKAWEDLRFSYSEMDETRSMLNTLWNSYAFSANYMVLDDFVPNNEYFKHVKDEDAWILSRINTVAKEAVEALEKPHLHVYTWALRDFILNDFSRWYIKLIRDRTWMEKNDVQKLSAYQTLYYVIMKLISIMAPVTPHLSEEIYQNLKTEDMPESIFMNKLTIESEFINETLEKDTEIIREIVDSILKGRDKAKYTLRYPITKITLPENIAETVEKYGYIIKEQGNVKEIELKEFEGNITVKPNFKELGKIFRSDVPKVVAAINSVAPNELKEKLKSGNFEVSEYEIKPEYVEFRVEIPENIVGVEFSKGNVYINIEMNDEVIKEGLVREVVRRIQSMRKDMDLDINEKINVKLEGIDFSSDYLSHIANEVRGNFVESLKSDYNQKWTIKTPNEETYDISIDIEKNK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_ALIFM
Sequence: MAAPGEALTQSGYIEHHLTNLSLAKLGLVADEASFWNVHIDSLFFSVFTGMLFLWVFRSVAKKATTGVPGKLQCFVEMIVEFVADNVKETFHGRNPLIAPLALTIFCWVILMNLMDLVPIDFLPYPAEHWLGIPYLKVVPSADVNITMAMALGVFALMIYYSIKVKGLGGFAKELALHPFNHPIMIPFNLLLEVISLLAKPLSLGMRLFGNMFAGEVVFILIAAMLPWYLQWVGALPWAIFHILVILIQAFVFMMLTIVYLSMAHEDSDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCL4_MOUSE
Sequence: MKLCVSALSLLLLVAAFCAPGFSAPMGSDPPTSCCFSYTSRQLHRSFVMDYYETSSLCSKPAVVFLTKRGRQICANPSEPWVTEYMSDLELN
What is the function of this protein?
Monokine with inflammatory and chemokinetic properties.
What are the official names of this protein?
C-C motif chemokine 4, Immune activation protein 2, ACT-2, ACT2, Macrophage inflammatory protein 1-beta, MIP-1-beta, Protein H400, SIS-gamma, Small-inducible cytokine A4.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECR_AGRVS
Sequence: MAKRVTGPEIEKLIQLLAKVPGLGPRSARRAALHLIKKREQLMGPLALAMGEAHAKVKICSCCGNVDTIDPCTVCTDERRDQSMIIVVEDVSDLWALERAGAMNVAYHVLGGTLSPLDGVGPDDLNIKGLIDRVAKGGVREIIIAVNATVEGQTTAHYITDHLAGLGVKTTRLAHGVPVGGELDYLDEGTLSAALRARTLI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: LEPA_PECAS
Sequence: MKHIRNFSIIAHIDHGKSTLSDRIIQICGGLTEREMAAQVLDSMDLERERGITIKAQSVTLDYKSQDGQTYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTALDMNLEVVPVLNKIDLPAADPDRVAQEIEDIVGIDATDAVRCSAKTGVGVPDILDRLVRDIPPPEGSPDAPLQALIIDSWFDNYLGVVSLVRIKNGTMRKGDKIKVMSTGQVYNADRLGIFTPKQIDRDVLNCGEVGWLVCAIKDILGAPVGDTLTLARQPAEKALPGFKKVKPQVYAGLFPISSDDYEAFRDALGKLSLNDASLFYEPESSTALGFGFRCGFLGLLHMEIIQERLEREYDLELITTAPTVVYEVETTAKETIYVDSPSKLPPLNNIQELREPIAECHMLMPQEYLGNVITLCIEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYGFKRFQTSDMVRVDVLINNERVDALALITHRDNSQYRGREFVEKMKELIPRQQFDIAIQAAIGNHIIARATVKQLRKNVLAKCYGGDVSRKKKLLQKQKDGKKRMKQVGNVELPQEAFLAILHVGKDSK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DNAA_STRPG
Sequence: MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATIYLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQALNSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHLLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQSLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNITPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQIDTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLARQVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEA_ESCF3
Sequence: MKTLIRKLTRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFSADVVAIAPDVAGLITNVNVHDNQLVKKGQVLFTIDQPRYQKALAEAEADVAYYSVLAQEKRQEASRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNTFYVLAYMEETKLEGVRPGYRAEITPLGSNRVLKGTVDSIAAGVTNASSTRDAKGMATIDSNLEWVRLAQRVPVRIRLDAQPENLWPAGTTATVVVTGKDDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL36_SHEB2
Sequence: MKVRASVKKICRNCKIVKRSGVVRVICVEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: VVP2_BOTJR
Sequence: PPPPPGPPPNP
What is the function of this protein?
Toxin.  Induces vasodilation in mice and rabbits.
What are the official names of this protein?
1095.6 Da venom vasodilator peptide.
What are the subcellular locations of this protein?
Secreted.
Protein: PHNW_BACCQ
Sequence: MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNMMVQQVRAKLVSLATKEEERYTTVLMQGSGTFSVEAVIGSVIPKNGKMLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKWRFTSPTHVVHAFYQALLELEKEGGVKARYNRYDNNQKLLVNRMREIGFKPLVDEKYQSPIITSFIYPEEWFDFEQLYNELKRDGFVIYPGKISKVDTFRIGNIGDVHEADIHRLVDSIAKGVVIG
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: IPYR1_ARATH
Sequence: MSEETKDNQRLQRPAPRLNERILSSLSRRSVAAHPWHDLEIGPGAPQIFNVVVEITKGSKVKYELDKKTGLIKVDRILYSSVVYPHNYGFVPRTLCEDNDPIDVLVIMQEPVLPGCFLRARAIGLMPMIDQGEKDDKIIAVCVDDPEYKHYTDIKELPPHRLSEIRRFFEDYKKNENKEVAVNDFLPSESAVEAIQYSMDLYAEYILHTLRR
What is the function of this protein?
Catalyzes the irreversible hydrolysis of pyrophosphate (PPi) to phosphate.  The MgPPi(2-) complex binds to the enzyme only after a free Mg(2+) ion has bound (Ref. 9).  No activity with glycerol-3-phosphate, glucose-6-phosphate, p-nitrophenylphosphate, ADP, NADP(+), NAD(+),NADH, NADPH or phosphoribosyl pyrophosphate as substrates (Ref. 9).  Controls the equilibrium of gluconeogenic reactions in the heterotrophic growth phase of early seedling establishment.  Determinates the rate of cytosolic glycolysis, providing carbon for seed storage lipid accumulation (PubMed:22566496).
What are the official names of this protein?
Soluble inorganic pyrophosphatase 1, Pyrophosphate phospho-hydrolase 1, PPase 1.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_XANC5
Sequence: MRRALRLLPLPLSIAICLPAMAADKPLNWGLCPAVDPLPGFDGAPAADPKAAEMRQQLPTDIEGDQLSGTSTTPQYQGNVALKRGDQFLGADNLRMDTETGNYIAEGNVRYQDTSFRMVADRAEGNQDTDTHKVTNIQYQLVERRGNGDAESVDLQGQVGQMHRSTYTTCDPSQPIWRVRAPEIDVDNEEGFGTARNAVLQIGKVPVLYFPWFKFPIDDRRQTGLLFPQFGLSGRNGFDYLQPIYLNLAPNYDATLLPRYMSKRGFMFGTEFRYLYEGGRGEVTGNYLPNDKLRDKDRGSVFYSGYHNVNSNWQARSSISWVSDTRYVEDFTSRINGMGSASSLQSTVGIYGTGETWTAGLMADRWQLTDYTLDEQALPYNRQPRAYFTWEKPLGIFEAGIYAEAVRFTHDDSYFVRPPISGSSRDDNEDEYVRTNIRNKQYGSGARLDVKPYISMPLSGAAWFLTPTVAWRYTAYQLDSTLADTAPLTGNRTPTRSLPIASLDAGLYFDRETSLFGTNYLNTLEPRMYYLYVPYRDQDDLPVFDTRPFTFSYGQLFRDTRYTGADRQNDANQLTLAVTSRWLRQDDGREKLSLSAGQILYFSDSLVTINNSNNSAAGSEQTVEQGKSAWVADANYMINDRWSMGATYQWNPNSRKEDLASLRTRYLLNNDGIINLAYRYRRNLTDNSDQLKQADFSFLYPINPSWSAVGRYYYSLLDRKPLEIIGGVQWDSCCLAVRGLVRRFVRNRDGEMDNSIQIEFVLKGLSSFGQNTDRTLRRAILGYYRDDLYLVPPSNTTTNPDDYDPNLIP
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: F16PA_KLEP3
Sequence: MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALRARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNRQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGNTYSINEGNYIKFPQGVKKYIKYCQEEDKETQRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPESLHQRRSFFVGNNHMVEDVENFIKAFPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V212_FOWPN
Sequence: MPQNKVLSFPLPEGTLLEDITKNKWILGKQLGSGGFGLVYQVSCKSKEIDCVAKIELKESGGLFCEINFYNRVMKNKTSLDTWMKEQKIDYIGIPSFHGFGITIYKNVEYRFAIIQRLGRDLENILSEKEKFNITVIKKLAIKILDILKFIHSKEFSHGDIKAGNILFGKDDDKVYLVDYGLATKYSSNGKHKEYTINPKNRHNGTMAFTSIDAHKGVTVSRRGDLESLGFCMLKWYSGKLPWEKYEKEPENVQGMKEAFVNNISKKTIPFKNAGIIYNYIKVVTKLEYEEAPNYESLKQMFL
What are the official names of this protein?
Probable serine/threonine-protein kinase FPV212.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.
Protein: PUR5_PROMP
Sequence: MDYKTSGVDIKAGREFVSEIKQSVESTYSSNVLEGIGGFGGLFKIPLEGLKKPVLVSGTDGVGTKLELAQIKNFHFEVGIDLVAMCMNDIITTGAKPLFFLDYIATGKLEKNQLLEVINGIAHSCRENKCSILGGETAEMPGFYSKNKYDLAGFCVGIADEEKLINGKKICENDLIIALQSNGMHSNGFSLVRKIIENNNQIDKQFEKKYNLDFYDELLKPTKIYFKIVNQILSQNIQIKGMSHITGGGIPENLPRCMSSDFIPYIDKKSWKIPVLFEFLKDVGQIPEKDFWNTFNLGVGFCLIIDKKYKDKILNICNAFDISSWVLGKVLKKNNSKENNFLPEIII
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTJ_PHOLL
Sequence: MIYWLFLAMAIITEVIGTLSMKHASVSGGVVGMAVMYIMIATSYILLAMAVKKVALGVAYALWEGVGILFITVFSVMWFDESLSLMKVGGLALLITGIMLIKSGTRKAAVKKSAEVVKQMANKAVSVATTKSSKIKEA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YL231_MIMIV
Sequence: MDEHIINLPFSNSLNSIDIVPLYLLTDKKIIDIAFEEIIGLIFHANFNLACDRTYKKHAYWDFLYKKFVKDIEKQNLAGWPIMTVNKNDYFNRIDIISIEKPFIDTDNILTLLHRLLYIENYKINAGYDNPVLKFKFIKLSCLEHSNIVENVSLYDLFSLLEKYLTYYVSKYGNVGNIENSLGSRILGLMR
What are the official names of this protein?
Uncharacterized protein L231.
Protein: ATPG_MANSM
Sequence: MASGKEIKTKIASVQSTQKITKAMEMVATSKMRKTQDRMAASRPYSETIRNVISHVSKASIGYKHPFLVEREVKKVGMLVISTDRGMCGGLNINLFKTVLNEIKKWKEQGITVEVGVIGSKGIAFFRSLGLKIRAQHSGMGDNPSVEELLGIANDMFDAYKDGKIDALYLAHNQFINTMSQKPSFAQLVPLPELDTDNLGERQQAWDYIYEPDPKMLLDSLLTRYLESQVYQSVVDNLASEQAARMVAMKAATDNAGNLINDLQLVYNKARQASITNELNEIVAGAAAI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RSAD2_DANRE
Sequence: MVTSNQLGFARLLMQLCVKNVQSFFLALLRWLSMQVSGAHVQQTPARKISRPESRTSKQKEGSRAPFTTPSSVNYHFTRQCNYKCGFCFHTAKTSFVLPIEEAKRGLRLLKEAGMEKINFSGGEPFVHQKGSFLGELVLYCKQELQLPSVSIVSNGSLIRESWFQKYGDYLDILAISCDSFIEETNQLIGRAQGRKSHLDNLHKVRNWCREYKVAFKINSVINTYNVEEDMTEQITALNPVRWKVFQCLLIEGENAGENSLREAEKFVISDQQFQDFLERHQSIQCLVPESNQKMRDSYLILDEYMRFLDCREGRKDPSKSILDVGVEEAIKFSGFDEKMFLMRGGKYVWSKADMKLEW
What is the function of this protein?
Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon.
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2, SAND, Radical S-adenosyl methionine domain-containing protein 2, Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible, Viperin.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RSAD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL11_FRASN
Sequence: MPPKKKKITALIKLQINAGKATPAPPVGPALGQHGVNIMEFCKQYNAATESQTGNVVPVEITVYDDRSFTFVTKTPPAARLILKAAGVDKGSGTPHRVKVAKLTPAQVREIAQTKLPDLNANSIEAAEKIIAGTARSMGITVGE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RLMN_BURM9
Sequence: MAGETIVNLLDLDAEGLVAYCGSLGEKAFRAKQLQRWIHQYNAADFDGMTDLAKSLREKLKGRAVIGTPDILSDHVSADGTRKWLINVGNGNAVETVFIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLSTGEIVGQLRMAEFALRASLGRAPGPNGKAERVITNVVMMGMGEPLLNYSAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLGAELPVALAVSLHAPNDALRDELVPLNKKHPLRELMAACQRYLKVAPRDFITFEYCMLDGVNDTEAHARELLAVTRDVPCKFNLIPFNPFPESGLVRSKTEQIKRFAQVLIDAGVVTTIRKTRGDDIDAACGQLAGAVKDRTRLAERTGASKIIEVRAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBE_CEBOL
Sequence: MVHFTAEEKVAITSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKTTFAKLSELHCDKLHVDPENFRLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALGHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RR11_SACHY
Sequence: MTKAIPKIGSRKKVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CDN2A_MONDO
Sequence: MGIVEKKEGGLERNRALFNSEGSCEGAKCGKEASMHTKHESEESFSGEKLTEAAARGRTEVVTELLELGTNPNAVNRFGRSAIQVMMMGNVRLAAILLQYGAEPNTPDPTTLTLPVHDAAREGFLDTLMLLHRAGARLDVRDSWGRLPVDLAEEQGHHLVVAYLREVVRDA
What is the function of this protein?
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6.  This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase 4 inhibitor A, CDK4I, Tumor suppressor CDKN2A, p16-INK4a, p16-INK4.
What is the protein family that this protein belongs to?
Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MUTL_STRP8
Sequence: MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITVEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKYMKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTTKKMLVISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYFGAVDNSVKVEKAELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLTRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: CB2B_SPIOL
Sequence: RKTAGKPKN
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein, LHCII type I CAB, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FABZ_BURMS
Sequence: MSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKAIKALKNVTVNEPFFTGHFPKRPVMPGVLIIEALAQAAALLTFAEAQPKDPENTLYYFVGIDNARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_CHLL2
Sequence: MPLQIFNTTRKELHEELLERTVIDVLDSEGFGVESIVAVYCGKKMIRKINREFLQHDYATDTITFRYSDNREIDGEFYISLDVIEENARRFEVDFKLELLRVTIHSALHLIGYDDQTVDGRLQMQQKEEFYLNRYSEANNQTPS
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAGK_STAAR
Sequence: MRKRARIIYNPTSGKEQFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE
What is the function of this protein?
Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid.  Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway.
What are the official names of this protein?
Diacylglycerol kinase, DAG kinase, DAGK.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
Protein: NNRD_MOUSE
Sequence: MAVHACGAAAAVVALLSAAIALQWSPLYAVLQRALSLHTAHATKDMENLFQLVRNIVPALTSKKHKGQDGRIGIVGGCQEYTGAPYFAGISALKVGADLTHVFCAREAAPVIKSYSPELIVHPVLDSSNAVEEVEKWLPRLHALVVGPGLGRDDLLLNNVRGILESTKARDIPVVIDADGLWLVAQQPALIHSYHKAILTPNHVEFSRLWEAVLSSPMDSNDLKGSTLKLSQALGNITVVQKGEQDLISNGQQVLVCNQEGSSRRCGGQGDLLSGSLGVMVHWALRAGPEKTNGSSPLLVAAWGACTLTRECNRQAFQKYGRSTTTTDMITEVGTAFSRLFTT
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase, Carbohydrate kinase domain-containing protein, NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
What are the subcellular locations of this protein?
Mitochondrion.