PharMolix/UniProtQA huggingface dataset:
Protein: P2Y12_HUMAN
Sequence: MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
What is the function of this protein?
Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system.  Not activated by UDP and UTP.  Required for normal platelet aggregation and blood coagulation.
What are the official names of this protein?
P2Y purinoceptor 12, P2Y12, ADP-glucose receptor, ADPG-R, P2T(AC), P2Y(AC), P2Y(cyc), P2Y12 platelet ADP receptor, P2Y(ADP), SP1999.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLYF_ASPFN
Sequence: MFSRIALLPAFLPVALACLGYEGGVPTPTAHYSNSAVIEIAAGEVFDAGWAKYDRGSGACGGQTEGDWKDAVFYLHSGATLKNVIIGADQSEGVHCDGACTLEFVWFEDVCEDAISIKNDKEGEETWIIGGGAYHADDKVVQHNGCGTVNIINFYAEDYGKVYRSCGNCSSQCKRNVYVEGTTARDGGEVVGINQSFGDTATLVNVCTDADHPCVLYDGCEGDCEPSKVGYCSG
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase F.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCD_BURM7
Sequence: MSIKSDKWIRRMAEEHKMIEPFVPDQVRAAEDGRKIVSYGTSSYGYDIRCADEFKIFTNINSTIVDPKNFDEGSFVDFKGDVCIIPPNSFALARTVEYFRIPRTVLTVCLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFFESDEVCDVSYADRGGKYQGQRGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PSBD_HETA4
Sequence: MTIAIGQNQERGVFDLVDDWLKRDRFVFVGWSGLLLFPTAYLAVGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSMGHSLILLWGPEAQGDFTRWCQIGGLWTFVALHGAFGLIGFCLRQFEIARLVGIRPYNAIAFSGPISIFVSVFLLYPLGQASWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLFEDGDAANTFRAFTPTQSEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWTSAIGIVGLALNLRAYDFVSQELRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DNAK_SALHS
Sequence: MGKIIGIDLGTTNSCVAIMDGTQARVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPYKIIGADNGDAWLDVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDTRLINYLVDEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDINDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTPLITKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRASDNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEEEIQKMVRDAEANAESDRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALSALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQAGSADASANNAKDDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: AHSA_DICDI
Sequence: MAKVGEGDPRWIVENREDGHNVNGWHWSEKDCLPWSKNTIGGLFDKKVIQETDEYTFKISSTPVVSGECTANNRKGKTIFLYELDVKMNWEVVFKPKKVLPPPPTTKSKGAADDIDEEDDDGKPAEPIITQKKTISGEFTVPYISDENGDEAPTVRYTINTTADNDETKQSINMVQSLLKSHGVPFVQSQCQEFIKLLKKEFVSKKQVEQSQQQQTANTTTNTTTTTNTVPKVTSSTVIFNSTPTKKPTTKTLKLKEEFQCSPMDAYDVFVNINKLRAFTQSDCTFENEEGGKFSLYGGSIQGVNKTLSPGSKIVQTWRLDNWSKGVESQVTITFSVDGKPLTNVEIVQTGIPIDEFEKTEEGWKRNILDRIKHTFSYSSKIF
What is the function of this protein?
Co-chaperone that stimulates hspD/HSP90 ATPase activity.
What are the official names of this protein?
Activator of 90 kDa heat shock protein ATPase homolog.
What is the protein family that this protein belongs to?
Belongs to the AHA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C102B_HUMAN
Sequence: MNLDSIHRLIEETQIFQMQQSSIKSRGDMVAPASPPRDTCNTCFPLHGLQSHAAHNFCAHSYNTNKWDICEELRLRELEEVKARAAQMEKTMRWWSDCTANWREKWSKVRAERNSAREEGRQLRIKLEMAMKELSTLKKKQSLPPQKEALEAKVTQDLKLPGFVEESCEHTDQFQLSSQMHESIREYLVKRQFSTKEDTNNKEQGVVIDSLKLSEEMKPNLDGVDLFNNGGSGNGETKTGLRLKAINLPLENEVTEISALQVHLDEFQKILWKEREMRTALEKEIERLESALSLWKWKYEELKESKPKNVKEFDILLGQHNDEMQELSGNIKEESKSQNSKDRVICELRAELERLQAENTSEWDKREILEREKQGLERENRRLKIQVKEMEELLDKKNRLSANSQSPDFKMSQIDLQEKNQELLNLQHAYYKLNRQYQANIAELTHANNRVDQNEAEVKKLRLRVEELKQGLNQKEDELDDSLNQIRKLQRSLDEEKERNENLETELRHLQNW
What is the function of this protein?
During interphase, forms fibers at the proximal ends of centrioles to maintain centrosome cohesion (PubMed:30404835).  During mitosis, dissociates from the centrosome following phosphorylation to allow centrosome separation (PubMed:30404835).  Contributes to CROCC/rootletin filament formation (PubMed:30404835).
What are the official names of this protein?
Coiled-coil domain-containing protein 102B.
Protein: IFT56_MACFA
Sequence: MMLSRAKPAVGRGVQPTDKKKKKGRKIPKLEELLSKRDFTGAITLLEFKRHVGEEEEDTNLWIGYCAFHLGDYKRALEEYENATKEENCNSEVWVNLACTYFFLGMYKQAEAAGFKASKSRLQNRLLFHLAHKFNDEKKLMSFHQNLQDVTEDQLSLASIHYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDSTIALNLKACNHFRLYNGRAAEAELKSLMDNASSSFEFAKELIRHNLVVFRGGEGALQVLPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMGSRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYNDDIFNFNYAQAKAATGNTSEGEEAFLLIQSEKMKNDYIYLSWLARCYIMNKKPRLAWELYLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIFQMIVAGREPKETLREVLHLLRSTGNTQVEYMIRIMKKWAKENRVPI
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium.  Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly.  Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU.  Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components.  Not required for IFT complex A ciliary localization or function.  Essential for maintaining proper microtubule organization within the ciliary axoneme.
What are the official names of this protein?
Intraflagellar transport protein 56, Tetratricopeptide repeat protein 26, TPR repeat protein 26.
What is the protein family that this protein belongs to?
Belongs to the IFT56 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Localizes at the base to the ciliary transition zone.
Protein: RS9_HALMA
Sequence: MVTNTSGKKKTAVARATVREGEGRVRIDSQPVELVDPELAQLKMLEPFRIAEDDLRGEVDVEVSVEGGGVMGQADAARTAIARGLVDHTNDAELRDAFMEFDRSLLVNDVRQSEPKKWGGPGARARYQKSYR
What are the official names of this protein?
30S ribosomal protein S9, F1, HS3, HmaS9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: DMPC_PSEUF
Sequence: MKEIKHFINGAFVGSASGRTFEDVNPANGQVIARVHEAGRAEVDAAVQAARAALKGPWGKMSVSERAEILHRVADGITARFDEFLEAECLDTGKPKSLASHIDIPRGAANFKVFADLLKNVATEAFEMATPDGSGAINYAVRRPKGVIGVISPWNLPLLLMTWKVGPALACGNTVVVKPSEETPLTTALLGEVMQAAGVPAGVYNVVHGFGPDSAGAFLTEHPDVNAITFTGETRTGEAIMRAAAKGVRPVSFELGGKNAGIVFADCDLDKAIEGSMRSVFANGGQVCLGTERLYVERPIFDEFVARLKAGAESLVIGTPDDPQANFGPLISLQHREKVLSYYQKAVDEGATVVTGGGVPEMPAELAGGAWVQPTIWTGLADGAAVVTEEIFGPCCHIRPFDREEEAVELANSLPYGLAATIWTENTSRAHRVAGQLEAGIVWVNSWFLRDLRTAFGGSKQSGIGREGGVHSLEFYTELKNICVKL
What is the function of this protein?
2-hydroxymuconic acid semialdehyde can be converted to 2-hydroxypent-2,4-dienoate either directly by the action of 2-hydroxymuconic semialdehyde hydrolase (HMSH) or by the action of three sequential enzymes, the first of which is HMSD.
What are the official names of this protein?
2-hydroxymuconic semialdehyde dehydrogenase, HMSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: AC100_MYCTO
Sequence: MRDRILAAVCDVLYIDEADLIDGDETDLRDLGLDSVRFVLLMKQLGVNRQSELPSRLAANPSIAGWLRELEAVCTEFG
What is the function of this protein?
Acyl carrier protein that accepts acyl-adenylates (acyl-AMP) from FadD10.
What are the official names of this protein?
Acyl carrier protein MT0109.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
Protein: TAL_CHESB
Sequence: MKFFVDTADVNEIRELSETGLLDGVTTNPSLIMKSGRPILEVTREICEIVDGPVSAEVTAVDFKEMMREADILSKIADNIAIKVPLTMDGLKACKALTSSGRMVNVTLCFSANQALLAAKAGATFISPFIGRIDDMGIDGMELIAEIRTIYDNYDFDTEILAASIRSVNHVKQAAIIGADVATVPPAVLKSLVKHPLTDKGLEAFLADWAKTGQKIG
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_THEMA
Sequence: MKKLTVYLATTNPHKVEEIKMIAPEWMEILPSPEKIEVVEDGETFLENSVKKAVVYGKKLKHPVMADDSGLVIYSLGGFPGVMSARFMEEHSYKEKMRTILKMLEGKDRRAAFVCSATFFDPVENTLISVEDRVEGRIANEIRGTGGFGYDPFFIPDGYDKTFGEIPHLKEKISHRSKAFRKLFSVLEKILESENR
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: SWC4_ASPFU
Sequence: MAAADVRDMLDLPAEGQPRPHKKQKVVEKRPDTDVQASEGITRELYALLGERAPPIAINENRYKGRPKWMSKLRVRPWQMTPFTNNARSDGLVLRHWQRQSESAKAPALEGASEMEVDQAKAGGGAATPEKEYPFAKYNVKPRVPRRYTDEEYNRHLKSDDWSRQETDYLMDLVEEYDLRWVVIADRYDFQPQPIDAEANATALVPAKQYRTMEQMKARYYFIAASMLALEHPPSEMSEAEFDLHEKMMKFDPDRERARKELAALQLNRTADEVREEGILLEELKRITSNEQNFMTERRELYSRLEVPISVGNTTMYQSSQGLSQLLQTLLQADKSKKRRSILGPEAAAPSPAGQTPTSNAPTSARDSRADTPSHASAGPSSKKGSTAAAAKEPPQTVKTLTPAEEARYGVQHHDRLVPGVQFRSDRAQKLTQAKSNVQSQKLATALAELEIPPRLLMPTERVCKEFEKLIHSVNLLLDARKVSEKIESEIRVLEAAREERERKTKEVKDKGKPEVKSEEVENSDSGAGDSASAAPTADERADERADKGLQGAEDPDQSTGDRDGVSHKRSASVLSNGSDKSTKRQKK
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
SWR1-complex protein 4.
What is the protein family that this protein belongs to?
Belongs to the SWC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: T23O_DROSI
Sequence: MSCPYAGNGNDHDDSAVPLTTEVGKIYGEYLMLDKLLDAQCMLSEEDKRPVHDEHLFIITHQAYELWFKQIIFEFDSIRDMLDAEVIDETKTLEIVKRLNRVVLILKLLVDQVPILETMTPLDFMDFRKYLAPASGFQSLQFRLIENKLGVLTEQRVRYNQKYSDVFSDEEARNSIRNSEKDPSLLELVQRWLERTPGLEETGFNFWAKFQESVDRFLEAQVQSAMEEPVEKAKNYRLMDIEKRREVYRSIFDPAVHDALVRRGDRRFSHRALQGAIMITFYRDEPRFSQPHQLLTLLMDIDSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPREAIPPLDETIRKKLINKSV
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Protein vermilion, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: SERC_AROAE
Sequence: MTRVYNFSAGPAALPEAVLQQAAEEMLDWQGAGCGVMEMSHRGKEFTSIVAQAEADLRELLAIPDNYRVLFLQGGATQQFAQIPMNLLAGGSADYLVTGSWSKKAYGEAKHLAGALGGAVRLAGSTETAGFTRLLRTEELDLDPRARYLHLCTNETIHGVELCEVSRLPDTGVPLVADMSSHILSRPLDIGRYGLIYAGAQKNIGPSGLVVVIVREDLLGHASPVTPTIMDYRVMAENGSMLNTPPTYAIYIAGLVFRWLKAQGGLAAVEANNIAKSDLLYDFLDASDFYENRVAQDSRSRMNIPFLLRDDALNDPFLAGAKAAGLTQLKGHKSVGGMRASIYNAMPLAGVQALVDYMRDFSARNG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFEO_ECO81
Sequence: MLHPRARTMLLLSLPAVAIGIASSLILIMVMKIASVLQNLLWQRLPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPGLIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALFGTPVAAALIFSQTLNGSNEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQMEMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVFVLGIGGLILGILGVIGGPVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVALGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVMLPAWLLLAGKPMMMVNRQKQQPPHDNV
What are the official names of this protein?
Putative ion-transport protein YfeO.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YD85C_YEAST
Sequence: MARGNQRDLARQKNLKKQKDMAKNQKKSGDPKKRMESDAEILRQKQAAADARREAEKLEKLKAEKTRR
What are the official names of this protein?
SERF-like protein YDL085C-A.
What is the protein family that this protein belongs to?
Belongs to the SERF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1964_GLUDA
Sequence: MMAEPTRRRVRGAASYQRGLQAEQVAGAWLQEHGWTILMHRARTRWGEIDLVAQRGAMIVFCEVKCRPHYTTAAESLGRAQMRRLMNAAAWLCAAHPGWIYDEMRFDVLLVTAGDAVHHIADAFRLE
What are the official names of this protein?
UPF0102 protein GDI1964/Gdia_0189.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: SPT6_DEBHA
Sequence: MAKEDIEEEREIRNDASENSSDEEGDDVLDSSEEDDDDDDEEAIKRVREGFIVDDDEDESQKRKRRKHKKRKREERTNDDENNALDQDDLELLMENSGARPQPSSNKLKRLKRAYTEDTEGAEEEEIGAKSGRGGLTDIFSDEDNNEEERADLGETRVDDDRNILDEFEDFIEEDEYSDEDEERQRKLTQQRERAQKKGPRLDTSKLSNVDRESLQQLFEVFGNGAEYEWALEAQEMEDEGNGENLEPTSLDEVFEHAELKERMLTEEDNLIRIVDIPERFQKYRANLNYIDLEGEELKSEQGWVANILFMEKQGSFSGFLEEPFKEAVSKVVEFISKDVYEVPFIWTHRRDFLLYSEEIKNEDGSVTNSVHKLLFEDDLWRIFQLDIEYHSLYEKRVNIEKLIESLNLDDDLVKDVKSLETMVAIQDLQDYINFTYSTEIRKLYDDKETEGIDANITKKHSKYAIFERIKSNVLYDAVNAFGISAKEFGENVQDQSSKKFEVPYRIHATDDHIESPEDLIERLCEDDEVLFKDPKNALNAVRKTFAEEIFHNPKIRHEVRTTFKDFASIRVAVTEKGKAIDNHSPYADIKYAINRSPADLVRNPDVLLRMLEAEAAGLVVVKVETKDYDSWFQCIFNCLKSDGSSEIFEKWNKEREFVLNMAFKRLTSMVSMNTKEDLRRECERLIASEVRRRFLARIDQAPFTPFGFDKGTKPNVLALSFGKGDFDSAVIGAFLRESGKVDEFFKSEDNPIRDRESEDKFSGQLKEFFDKNLRNQKPDVIVVSGYNAISKKLFDSVKSFVETNNVTANTEELTDVQNPPLIQVIWGQSETATLFQNSERARIEFSDKPTLAKYCVGLARYVQSPLLEYLSLGEGILSLTFFEHQKLISTDLVMEAIESAYVDIINMVGVEINEAIRDPYIAQLLPYVAGLGPRKASGLLRNINSKLGSTLANRSDLIENELSTANIFINCSSFLNIPYDEGLSMRDSSVELLDATRIHPEDYDLARKMAADALDLDEEDMAHVEEQGGIIYQLMQDGVNKVDDLNLTAYGKELESKFGKKKYATLQSIKEELVNNFEEIRRSFHILESHEVFHMLTGETTESFTRNTIVPVTVNKVGQNFRDFENSKIKFAKVTTSSFIQGNIEEASIPQGIDLAQGQVVQAVVLDAYYDSFTASFSLLEADIQKGAAPKFHKDPLKWNFEAEQADKQKEMAKERAQLAKTRNIQHPLFHNFSYKQAEEFLAPQAVGDCVLRPSSKGPNYLTVTWKVSNNLFQHLSIQENTQGMGKEYIVEHKKYADLDQLIFQHVQAIAKHVDEMCRHPKFREGTMSEVNEWLESYTKANPKNSAYVFCFDHKAPGWFLLLFKVNVNTPITTWHVKTECDGYRLKGFSYPSMLRLCNGFKQTFKSYVKGIADRSRSTKPAPVNNQAQASTYGGYGY
What is the function of this protein?
Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters.  Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT6, Chromatin elongation factor SPT6.
What is the protein family that this protein belongs to?
Belongs to the SPT6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS4_META3
Sequence: MGDPRRLSKTYDTPNHPWIGERIKQERELSNKYGLSNKKEIWKMETRLRTFRRQARKLISDTSAQGEKEAVQLFGILNRYGILLKEDATLDDVLSLNLESILERRLQTLVFRKGLANTPKQARQFIVHGHIAVNGKKINAPSYLVPLVEEDAISYMPNSPMASESHPERTDSVKDAE
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: YO81_BPP2
Sequence: MFCSRAVVLLNNALKIAVMKNGDLSLIQLGLDKEKREITESVIAIYQSELNLLSDVVNLLVKRAVFHKQISSVDELTKLTTEIASYCADEFKKLNDKRNW
What are the official names of this protein?
Uncharacterized 11.3 kDa protein in GpA 5'region, ORF2.
Protein: PURL_RHOE4
Sequence: MSAHQVDTVTHASADPDAAQPFKELGLKDDEYARIKEILGRRPTDAELAMYSVMWSEHCSYKSSKVHLGYFGKTTTDEMRANMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPIAVMDQLRFGAADAPDTRRVVDGVVRGVGGYGNSLGLPNIGGETVFDESYAGNPLVNALAAGVMRVEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASATFDDEGGDTGGRKKLPAVQVGDPFTEKVLIECCLDLYKAGLVVGIQDLGGAGLSCATSELAAAGDGGMHINLEKVPMRATGMTPAEVLSSESQERMCAVVTPENVDAFMEVCKKWDVLATDIGEVTDGEHLTISWHGETVVDVPPRTVAHEGPVYNRPVERPASQDALIANTTAGLKRPETDAELEATLLKMIASPALCSRKWITEQYDRYVRGNTVLAENADGGVIRIDEKTGRGIALSTDASGRYTALDPYTGAQLALAEAFRNVAVTGATPKAVSNCLNFGSPEDPGVMWQFQQAVRGLADGCATLGIPVTGGNVSFYNQTGSTAILPTPVVAVLGVIDDVHRRIPTGLGLEPGETLILLGDTHDEFDGSIWSQVEHGHLGGVPPKVDLAREQLLADILLASSRDGLVTAAHDLSEGGLAQAVVEAALAGETGCRILIPEGADPFVTLFSESSGRVLVAVPRTEETRFTGMCTARGLPWTRIGVVDEGSDSVEVQGHFSVTMAKLREAFEGTLPALFG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_STRSY
Sequence: MSKEIIAKAQERMNQSHQSLAREFSHIRAGRANASLLDRISVEYYGSPTPLNQLAGITVPEARVLLITPFDKSILKDIERALNASDLGLTPQSDGTVIRLVIPALTEETRKNLAKDVKKVGENSKVAIRNIRRDAMDEAKKAEKAKEITEDELKTLEKDIQKVTDDAIKTIDKMTADKEKELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_ECO5E
Sequence: MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIRVVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQMVEKEAQEQGKPLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_SALEP
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRGALAQEATQEHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RL24_ECO81
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNATTGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.