PharMolix/UniProtQA huggingface dataset:
Protein: MURD_ACAM1
Sequence: MPAVHIIGLGRSGIAAARLLRREGWQVSVGDAGHSEGLVATQKTLAAEGIPVHLNLKFSLSALAELSLDRPDRIVVSPGVPWQLPALEEARSQGIETFGELELAWRSLKQYPWVGITGTNGKTTTTAIVEAIFKAAGLRAPACGNIGYSACELALAGDPLDWVIAEVSSYQIESSPTLAPTIGVWTTFSPDHLERHGTVECYREIKALLLNQSKQKILNGDDQGLIKGLPWRWADAYWTSSHGPSLPDACNGQRCPVPNIFIEEGWVKVEGEPIVQVSSMRMLGVHNQQNLLLAVAVAHLAGIGKDAIATAVSTFPGVAHRLEHICTWQGVDFINDSKATNYEAAQTGLAAVNSPAILIAGGEAKVGDDQAWLQTIQAQAAKVLLIGSAAGAFSQRLKAIGYDDYEIVDTMNKAVTRAAELAPSLQAKSVLLSPACASFDQYQNFERRGDHFRQLCQDLSQ
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_MOOTA
Sequence: MPRVALYNIQGQQVGEVDLDDSVFGGEVNEAVLHDAVVMQLASRRRGTAATRGWADVSGGGRKPWRQKGTGRARAGSIRSPLWRGGAVIFGPQPRDYGYRLPKKVRRLALRSALASKVRDGNIIVLDELKMEKPRTKDMAHILKNLNAENKALVVTATREPNVELSARNLPGVRFLTSDGINVYDLLAHDKLVITKDAVARVQEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: IEND2_NEUCR
Sequence: MNITLILFLIGILGFVLNRKNIILMLISIEIMLLAITFLILVSSLNMDDIIGQTYAIYIIVVAGAESAIGLAILVAFYRLINSPVKNPRSNYSGDPAPPSGGRGPYLHFNLLPVVSSCNLIQSRNYSSVLHRKIPTHTSCVWAGLNPSFITGFSDAEGSFVVTILKNPRYKIGWNVQARFQIKLNEKDRALLLLIQNYFDNIGYISKINDRSTVEFRVSDITSLNNIIIPHFEKYQLITNKYGDLVIFKQIVSLMLENKHTTLEGLKEILEHRASLNWGLSKTLKESFPSIIPVKRVKIENNILSNLSSLPLLPGGGNWVAGFSSGEANFFITMSGTKVWLRFSIAQDSRDILLLKSLVKFFNCGYIAQYKNRKVCEFIVTKINDIIIYIIPFFDQYKIEGSKYNDYVKFKEAAILIKNKEHLTEKGLNKIIELKNSLPPPASLEGGMNKNI
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded endonuclease 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: YBGE_ECO57
Sequence: MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTSELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF
What are the official names of this protein?
Uncharacterized protein YbgE.
Protein: MSHR_MACMU
Sequence: MPVQGSQRRLLGSLNSTPTATPHLGLAANQTGARCREVSIPDGLFLSLGLVSLVENVLVVTAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLETAVTLLLEAGALVARAAVVQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRAQRAIAAIWVASVLCSTLFIAYYDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRLAHQGFGLKGAATLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLALIICNAIIDPLIYAFRSQELRRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GVP35_DACSA
Sequence: VSLREQWNEQARERQREISARKTEIEEARSSIQKELQAQYEAALAATQQLQSLXXRFXRFY
What is the function of this protein?
May confer stability to the gas vesicle membranes.  Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.
What are the official names of this protein?
35 kDa gas vesicle protein C.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type C family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: RPPH_RICAH
Sequence: MRNSSKKHLDLPYRLGVGMMILNADNHIFVGKRIDTKLSAWQMPQGGIVPGETPSIAAMREMLEEIGSDKGYIIAESKCWYSYDVPSLLIPKLWNGNFRGQKQRWFLIRFTGNNEDININTSNPEFDQWRWASLDELLSIIIPFKRKLYQAVVKEFKSLIQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: IF1C_SAMCA
Sequence: MKEQKWIHEGLITESLPNGMFRVRLDNEDMILGYVSGKIRRSFIRILPGDRVKIEVSRYDSTRGRIIYRLRNKDSKD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
Protein: CURC2_MOLLA
Sequence: MAAKFLLTILVTFAAVASLGMADSVLLSGQTLYAGHSLTSGSYTLTIQNNCNLVKYQHGRQIWASDTDGQGSQCRLTLRSDGNLIIYDDNNMVVWGSDCWGNNGTYALVLQQDGLFVIYGPVLWPLGLNGCRSLNGEITVAKDSTEPQHEDIKMVINN
What is the function of this protein?
Taste-modifying protein; sweet-tasting.  After curculin, water elicits a sweet taste, and sour substances induce a stronger sense of sweetness.
What are the official names of this protein?
Curculin-2, Neoculin acidic subunit, NAS.
Protein: Y1380_METJA
Sequence: MSKRDVKAFLYDILESANDVIEFTKDIDYNEFINNKMIRYAVIRALEIIGEASRYINNDFREKFPNVPWKEMVGLRNILIHKYFGIDYILLWKIVKEDVPKIKKEVEIV
What is the function of this protein?
Probable toxic component of a putative type VII toxin-antitoxin (TA) system, probably an RNase.  Probably neutralized by cognate antitoxin MJ1379.  Neutralization may be due to AMPylation by antitoxin MJ1379.
What are the official names of this protein?
Putative RNase MJ1380, Putative toxin MJ1380.
What is the protein family that this protein belongs to?
Belongs to the HepT RNase toxin family.
Protein: FPG_PECAS
Sequence: MPELPEVETSRRGISPYLVGHTILYAEVRNARLRWPVSAEILSLSDEPVLSVRRRAKYLLIELTHGWIIVHLGMSGSLRILPEYSEPEKHDHVDLVMDSGKVLRYTDPRRFGAWLWTDSLETSSVLAHLGPEPLEAEFFADYLYQASRGKKTAIKQWIMDNKVVVGVGNIYASESLFAAGIHPDRAAGSLNENDADVLVRVIKQVLQLSIEQGGTTLRDFLQSDGKPGYFAQELRVYGRNGEPCRTCGTPIETAKHGQRSTFFCRRCQV
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SYW_STRR6
Sequence: MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLADQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLVSLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIEQTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDADTLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLGDVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGAMGLHYFN
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_LISMH
Sequence: MARKTNTRKRRVKKNIESGIAHIRSTFNNTIVMITDTHGNALAWSSAGSLGFKGSRKSTPFAAQMAAESAAKSAQEHGLKTLEVTVKGPGSGREAAIRALQAAGLEVTAIKDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: NUOI_METRJ
Sequence: MKLDQVAKSLLLKEFVSGMILGMRYFFKPKATINYPFEMGHRGPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIEAGPRRNDGTRRTTRYDIDMVKCIYCGMCQEACPVDAIVEGPNFEFSVETREELLYDKQKLLLNGDRWEREIARNIAMDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BFD_SALTY
Sequence: MYVCLCNGISDKKIRQAVRQFHPQSFQQLRKFIPVGNQCGKCIRAAREVMQDELTQMPEFKEIA
What is the function of this protein?
Seems to associate with BFR; could be a general redox and/or regulatory component participating in the iron storage mobilization functions of BFR.  Could participate in the release or the delivery of iron from/to bacterioferritin (or other iron complexes) (By similarity).
What are the official names of this protein?
Bacterioferritin-associated ferredoxin.
Protein: HIS3_BRUSU
Sequence: MSIFPAQPSDKKAVEEGAAFMPRFDASGLITAIVTDARDGELLMVAHMNEEALRLTLETGIAHYWSRSRKTLWKKGETSGNLQSVVELRTDCDQDALWLKVHVAGDGPTCHTGRRSCFYRQVVSSGGKVALTMVSDHDQ
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIPA_ACET2
Sequence: MRKVISMLLVVAMLTTIFAAMIPQTVSAATMTVEIGKVTAAVGSKVEIPITLKGVPSKGMANCDFVLGYDPNVLEVTEVKPGSIIKDPDPSKSFDSAIYPDRKMIVFLFAEDSGRGTYAITQDGVFATIVATVKSAAAAPITLLEVGAFADNDLVEISTTFVAGGVNLGSSVPTTQPNVPSDGVVVEIGKVTGSVGTTVEIPVYFRGVPSKGIANCDFVFRYDPNVLEIIGIDPGDIIVDPNPTKSFDTAIYPDRKIIVFLFAEDSGTGAYAITKDGVFAKIRATVKSSAPGYITFDEVGGFADNDLVEQKVSFIDGGVNVGNATPTKGATPTNTATPTKSATATPTRPSVPTNTPTNTPANTPVSGNLKVEFYNSNPSDTTNSINPQFKVTNTGSSAIDLSKLTLRYYYTVDGQKDQTFWCDHAAIIGSNGSYNGITSNVKGTFVKMSSSTNNADTYLEISFTGGTLEPGAHVQIQGRFAKNDWSNYTQSNDYSFKSASQFVEWDQVTAYLNGVLVWGKEPGGSVVPSTQPVTTPPATTKPPATTKPPATTIPPSDDPNAIKIKVDTVNAKPGDTVNIPVRFSGIPSKGIANCDFVYSYDPNVLEIIEIKPGELIVDPNPDKSFDTAVYPDRKIIVFLFAEDSGTGAYAITKDGVFATIVAKVKSGAPNGLSVIKFVEVGGFANNDLVEQRTQFFDGGVNVGDTTVPTTPTTPVTTPTDDSNAVRIKVDTVNAKPGDTVRIPVRFSGIPSKGIANCDFVYSYDPNVLEIIEIEPGDIIVDPNPDKSFDTAVYPDRKIIVFLFAEDSGTGAYAITKDGVFATIVAKVKSGAPNGLSVIKFVEVGGFANNDLVEQKTQFFDGGVNVGDTTEPATPTTPVTTPTTTDDLDAVRIKVDTVNAKPGDTVRIPVRFSGIPSKGIANCDFVYSYDPNVLEIIEIEPGDIIVDPNPDKSFDTAVYPDRKIIVFLFAEDSGTGAYAITKDGVFATIVAKVKSGAPNGLSVIKFVEVGGFANNDLVEQKTQFFDGGVNVGDTTEPATPTTPVTTPTTTDDLDAVRIKVDTVNAKPGDTVRIPVRFSGIPSKGIANCDFVYSYDPNVLEIIEIEPGDIIVDPNPDKSFDTAVYPDRKIIVFLFAEDSGTGAYAITKDGVFATIVAKVKEGAPNGLSVIKFVEVGGFANNDLVEQKTQFFDGGVNVGDTTEPATPTTPVTTPTTTDDLDAVRIKVDTVNAKPGDTVRIPVRFSGIPSKGIANCDFVYSYDPNVLEIIEIEPGELIVDPNPTKSFDTAVYPDRKMIVFLFAEDSGTGAYAITEDGVFATIVAKVKSGAPNGLSVIKFVEVGGFANNDLVEQKTQFFDGGVNVGDTTEPATPTTPVTTPTTTDDLDAVRIKVDTVNAKPGDTVRIPVRFSGIPSKGIANCDFVYSYDPNVLEIIEIEPGDIIVDPNPDKSFDTAVYPDRKIIVFLFAEDSGTGAYAITKDGVFATIVAKVKEGAPNGLSVIKFVEVGGFANNDLVEQKTQFFDGGVNVGDTTVPTTSPTTTPPEPTITPNKLTLKIGRAEGRPGDTVEIPVNLYGVPQKGIASGDFVVSYDPNVLEIIEIEPGELIVDPNPTKSFDTAVYPDRKMIVFLFAEDSGTGAYAITEDGVFATIVAKVKEGAPEGFSAIEISEFGAFADNDLVEVETDLINGGVLVTNKPVIEGYKVSGYILPDFSFDATVAPLVKAGFKVEIVGTELYAVTDANGYFEITGVPANASGYTLKISRATYLDRVIANVVVTGDTSVSTSQAPIMMWVGDIVKDNSINLLDVAEVIRCFNATKGSANYVEELDINRNGAINMQDIMIVHKHFGATSSDYDAQ
What is the function of this protein?
Acts as a scaffolding protein in the cellulosome.  It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes.
What are the official names of this protein?
Cellulosomal-scaffolding protein A, Cellulose-integrating protein A, Cellulosomal glycoprotein S1/SL, Cohesin.
What are the subcellular locations of this protein?
Secreted. Note=Remains at the cell surface.
Protein: MPAB2_PENBR
Sequence: MSLSLPPALSELARALPYSRTQWLPILVGFLIGYPLLIKALRYKRLGEMKKKFYFPTRESMAEMTDEEAFLIQKEMAQLEFPFMFLTSGQFALFRTYGIPTISHLLTKTGQFSKPETSFKRYTDTAALIGEMVENSPTSQRAFISVARTRFLHSGYQASGKILDADLLYTLALFAVQPVRFIENFEWRTLSDLELCAIGTFWKSLGDALGISSEILPSGKTGFKDGIQWLEEVDVWSQDYEAKYMVPDPKNRESADQATAVLLYNLPKILHPIGLQFTSYMMDDRLRKAMLYEAPSPGWSAVFSSLLATRKFVLRYLSPPRPAALAVSNIAQKPDKDDRYHRMSWDALPFYIRPTFWNRWGPMAWISWLMAHPVPGDHGQKYYPQGYHIQDIGPKYFEGKGHKEIQEMMKELKISRTGKCPFH
What is the function of this protein?
ER-bound oxygenase; part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893 (PubMed:31209052).  MpaB' catalyzes the oxidative cleavage the C19-C20 double bond in farnesyl-DHMP (FDHMP) to yield FDHMP-3C via a mycophenolic aldehyde intermediate (PubMed:31209052).  The first step of the pathway is the synthesis of 5-methylorsellinic acid (5MOA) by the cytosolic polyketide synthase mpaC.  5MOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) by the endoplasmic reticulum-bound cytochrome P450 monooxygenase mpaDE.  MpaDE first catalyzes hydroxylation of 5-MOA to 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoic acid (DHMB).  MpaDE then acts as a lactone synthase that catalyzes the ring closure to convert DHMB into DHMP.  The next step is the prenylation of DHMP by the Golgi apparatus-associated prenyltransferase mpaA to yield farnesyl-DHMP (FDHMP).  The ER-bound oxygenase mpaB then mediates the oxidative cleavage the C19-C20 double bond in FDHMP to yield FDHMP-3C via a mycophenolic aldehyde intermediate.  The O-methyltransferase mpaG catalyzes the methylation of FDHMP-3C to yield MFDHMP-3C.  After the cytosolic methylation of FDHMP-3C, MFDHMP-3C enters into peroxisomes probably via free diffusion due to its low molecular weight.  Upon a peroxisomal CoA ligation reaction, catalyzed by a beta-oxidation component enzyme acyl-CoA ligase ACL891, MFDHMP-3C-CoA would then be restricted to peroxisomes for the following beta-oxidation pathway steps.  The peroxisomal beta-oxidation machinery than converts MFDHMP-3C-CoA into MPA_CoA, via a beta-oxidation chain-shortening process.  Finally mpaH acts as a peroxisomal acyl-CoA hydrolase with high substrate specificity toward MPA-CoA to release the final product MPA (PubMed:31209052) (Probable).
What are the official names of this protein?
ER-bound oxygenase mpaB', Mycophenolic acid biosynthesis cluster protein B'.
What is the protein family that this protein belongs to?
Belongs to the mpaB oxygenase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SECA_BIFAA
Sequence: MVDIVDKALRMGEGRQIKKLENVAKATNALEDEIAALDDEELKGQTAKFKQRIENGESLDKLMPEAFATVREASKRTLGLRHFDVQLMGGAALHWGNIAEMKTGEGKTLVATLPAYLNALDGQGVHVVTVNDYLASYQAELMGRVYRFLGMSTGCIITNQKPPERRKQYNADITYGTNNEFGFDYLRDNMAWEKSDLVQRGHHYAIVDEVDSILIDEARTPLIISGPAEGDVTRWYRQFARLVLKLNRDEDYEVDEKKKVVGILDPGITKVEDYLGIDNLYEPNNTALIGYLNNAIKAKELFLRDRDYVVTGGEVLIVDEHTGRILPGRRYNEGLHQAIEAKEGVEVKAENQTFATITLQNYFRMYDKLAGMTGTAETEAAEFMGTYKLGVLPIPTNKPMIREDKDDLIFRTKKEKLAAIVRDVAKRHKKGQPVLLGTASVESSEVVSSLLDVAKIPHQVLNAKQHDKEAAVVAVAGRKGAVTVATNMAGRGTDIMLGGNVEFLADAKLKSEGYSPDDTPDEYEKRWPGTLAEIKDQVKDEHEEVVKLGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLEDDLMRLFNTQLVARVMAKGMPEGEPIEAKSVSKGVRTAQKAVESRNFEIRKNVLKYDDVMNKQRTVIYAERQAVLKGADIHEDILKFIDDTVLSYIKGANNGSDKPADWDWDGLFKAISSVYPIAVEQEGAKDAVDKLKGDKAVEALKELIVSDAKDQYSDFEDKLGSEGLRQLERRVVLAVLDRKWREHLYEMDYLKDGIGLRGMGQRDPLVEYQREGYQMYNSMIEAIKEETIQLLFHVDIERVAMTEDEETESDEDEAVNAAEAVMGLDGEAAATGESAPAEPETDDEAEKTTIDELADEQKNEKGIVGMQPISHAEGKVPANKRPKSEELHSPWADGRTFPGTGKNAQCPCGSGRKYKMCHGQNEQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: UPP_RUMCH
Sequence: MENVFVFDHPLIQHKISLLRDKNTNTKEFRELVSEIAMLMGYEVTRNMPLKEVEIETPIGMAKTKVISGKKLGIVPILRAGLGMVDGMLRLIPMAKVGHIGLYRDPESLQPVEYYCKLPVDVEEREIVVLDPMLATGGSASAAIQFIKNRGVKNIKLMCLIAAKAGIERMQKDHPDVGIYCASVDEILNDHAYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CF210_BOVIN
Sequence: MLVRFGRRSGQAKESAEMKNCEEDPVLYPPLLPTKVDLRQVTIIPHNEWERIRDSLDSLTREAACLRAERKAKKEMHLRSQEVVKHWTNTYAGMKEQKLEAKKKRDEEIEAERQILDIEEAIYKQGERKKAIELAKQYQFYQTERVKNFHSGLLLSRVMKERDAQIEFQKSKIKSDKKWEEQVKLNVEKAFKEEREKAEKQRRERVALAKDHLKQIKEHEEEEERRRKEEEKDAEEIKRQNSLYEIEMKKKQGKKKEEINESRRLFFEHLNDKHIIKAVEQQQQEEEDEKIRKFIKAKKRLTQMGKEKEAETHRLMEERRKRINNFLSKLMKEKFDNEDLIIARDIAEAEAEWEKREREKYEKNKAELKAIAEHRALVMKNKEEEERQRKIEATEQMLAILKADQIFWEHEKEKKQKADKERREVQDAHIQQMAKHKFNALQAKQAESEYCRLTEALVAEKEKEFQDYAREVIESESESTKKYIYPLVKAVQEGPGGGRGPVLVDRGGLRPSYQANDTTGVQLPFYNSPGSKYNNFQKSKGRLGFTW
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Cilia- and flagella- associated protein 210.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: KDPA_MYCSK
Sequence: MSTTTAGILFALSLALALAAVHVPLGDYMYRVYASEKHWRAERVAYRIIGADPAAEQGWGSYARSVLAFSAVSILFLFGLQLLQGRLPLHLNDPATEMTPALAWNTAVSFVTNTNWQAYSGESTQGHLVQMAGLSVQNFVSAAVGMAVAMAFVRGLARRDTGELGNFWVDLIRGSLRILLPLSIIGAIILVSGGVIQNFALHDTVVSTLSGAQQTIPGGPVASQEAIKELGTNGGGFFNANSAHPFENPTTWTNWVEIFLLSCIAFSLPRTFGRMVGSRKQGAAILAVMAVIATLSLSLMMLFQSQTHGTVPTAVGSATEGVEQRFGVADSAVFADLTTLTSTGAVDSFHDSYTSLGGLMTLFNMQLGEVAPGGVGSGLYSMLVLAVITVFVAGLMVGRTPEYLGKKITPREIKLAATYFLVTPLIVLIGTAVAMALPGQRDGMLNTGPHGLSEVLYAFTSAGNNNGSAFAGLSVNTEWYNTALGLAMVFGRFLPIILVLALAGSFARQGRTPESVGTLPTHRPQFVGMVTGVTLILVALTFLPVLALGPLAEGLH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL10_RHOPA
Sequence: MVLLAGTANRRELAVERAAKKEAVESLNGLFQTTSVAIVAHYSGLTVAQMQKLRQQMKQAGASVKVSKNRLAKIALEGTDVAAIGPLLKGPTVIATSSDPVAAPKVAVEFAKANEKFVILGGSMGTTVLNVDGVKALASLPSLDELRAKLVGLVQAPATKIAQVTTAPAAKLARVVQAYASKSEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, RRP-L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: HIS3_PELTS
Sequence: MPFDLDSLKYNEAGLVPAIVQDAGTGAVLMMAYMNREALEKTLATGETWFWSRSRKAFWHKGETSGNVQRVKEVLYDCDRDTLLVKVEQHGAACHEGYYSCFHYRLERDGSVTVVGEKQFDPEQVYGKR
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y642_METJA
Sequence: MITMALNFYKYYSRQIKYALHFNILNNSIIDAENKYINFQKPLKNVIVSDSMFIDTAYLLKIKKMIKSIKGVFWADFVLKKYYPLYSDYLKGKISNVGTDGKINYGEILNINPDMIFLIDWNIFNPLSKWLDKNNIPYTKTGNYKEPKFLGKMEWIKFYASFYNKYKKAEKVFNKIIEEKRRILKSLNSRSIKYKPVVAFFGYHKNQPYIYGKSHYIPNWIREIKGNYLFENVEGTNYHYIDRKIFNSRAKYADVCILDTMGEDIDIKELLKNNPHFLKFRAYKNKRFYITTKDYLKFETLKCSEVMEEYVKIIHPKIYQNGDNDLKYFIKVV
What are the official names of this protein?
Uncharacterized protein MJ0642.
Protein: TX143_LYCSI
Sequence: MKFVLLFGVLLVTLFSYSSAEMLDDFDQADEDELLSLIEKEEARKDCIPKHHECTSNKHGCCGGHLFKYKCQCTTVVTQSGEETERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1aa, Toxin-like structure LSTX-A43.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL28_STAAM
Sequence: MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CH10_BORPD
Sequence: MALRPLHDRVIVKRLDNERKTASGIVIPDSAAEKPDQGEVVAVGPGKKTEDGKVLPVDLKAGDKVLFGKYAGQSVKVDGEELLVIREEEILAVIQ
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.