PharMolix/UniProtQA huggingface dataset:
Protein: RL13_LACH4
Sequence: MRTTPLAKSSEIERKWYIIDATDVSLGRLSAAVATILRGKNKPQYTPNVDTGDNVIVINASKIKLTGKKASDKFYYHHSEWRGGLKAVSYGELLANNPVKMVEISVKGMLPKNTLGHHEFMKMHVYAGEDHKHEAQKPEKLDINKLI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: UVRC_BACCQ
Sequence: MHEHLKEKLAILPDQPGCYLMKDKQGTVIYVGKAKVLKNRVRSYFTGSHDGKTLRLVGEIVDFEYIVTSSNLEALILELNLIKKHDPKYNIQLKDDKTYPFIKITAEKQPRLLITRNVKKDKGKYFGPYPNAQSAHETKKLLDRMYPLRKCSNMPDKVCLYYHMGQCLAPCVKEVTEEQNKEIVDEIIKFLNGGHKEVRSELETKMYEASEKLEFERAKELRDQIAHIDAIMEKQKMIMSDLVDRDVFGYAVDKGWMCVQVFFVRKGKLIERDVSMFPIYDEPEEGFLTFIGQFYENSSHFKPKEIVVPGSIDSELVERFLEVEATQPKRGKKKDLVELANKNAKIALEEKFYLIERDEERTIKAVENLGEQLGIETPYRIEAFDNSNIQGTNPVSAMIAFIDGKPAKKEYRKYKIKTVQGPDDYESMREVVRRRYTRALKEGLPLPDLIIIDGGKGHLAAASDVLENELGLYIPMAGLVKDDKHKTSHLIIGDPPEPVMLERNSQEFYLLQRIQDEVHRFAITFHRQLHGKSVIQSALDDIPGIGDKRKKILLKHFGSLKKMKEASVTEFVEAGMPKNVAETIYSYLADKKTL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNPEP_RICCO
Sequence: MAKQDSQTEGISIDSDLINFLNASPTAFHAIDEAKKRLKHSGYVQVSERDDWKLELGKRYFFTRNHSTIVAFAIGKKYVAGNGFYVVGAHTDSPCIKLKPVSKVTKSGYLEVGVQPYGGGLWHTWFDRDLAVAGRVIVREEKHGSVSYSHRLVRIEEPIMRVPTLAIHLDRNVNTDGFKVNTQSHLLPVLATSVKAELSKVVAENGTVGNDEETDGMKSSKGTTNANSKHHSLLLQMIAGQIGCNGSDICDFELQACDTQPSVIAGAAKEFIFSGRLDNLCMSFCSLKALIDATASDSHLENESGVRMVALFDHEEVGSDSAQGAGSPVMFDALSRITSTFNSDSKLLRKAIQKSFLVSADMAHALHPNYADKHEENHQPRMHGGLVIKHNANQRYATNSVTSFLFKEIASKHNLPVQDFVVRNDMPCGSTIGPILASGVGIRTVDVGAPQLSMHSIREMCAVDDVKYSYEHFKAFFEDFSHLDSKITVDM
What is the function of this protein?
Likely to play an important role in intracellular protein and peptide metabolism.
What are the official names of this protein?
Probable aspartyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNP29_RAT
Sequence: MSGYPKSYNPFDDDVEDEDTRPAPWKDARDLPDGPDPPIDRQQYLRQEVLRGPSATAASTSRSLFLMYESEKIGVASSEELVRQRGVLEHTEKMVDKMDQDLKMSQKHINSIKSVFGGFINYFKSKPVEPPPEQNGSIVPQPSSRLKEAINTSKDQESKYQASHPNLRRLHDAELDSVPASTVNTEVYPKNSSLRAYHQKIDSNLDELSVGLGRLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTEKKVRQL
What is the function of this protein?
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes.  SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.  SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane.  Also plays a role in ciliogenesis by regulating membrane fusions.
What are the official names of this protein?
Synaptosomal-associated protein 29, SNAP-29, Golgi SNARE of 32 kDa, Gs32, Soluble 29 kDa NSF attachment protein, Vesicle-membrane fusion protein SNAP-29.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Cell projection, cilium membrane; Peripheral membrane protein. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic. Localizes to the ciliary pocket from where the cilium protrudes.
Protein: ISPG_PARD8
Sequence: MAYFNYNRRKSSVAQIGDTPMGGENPIRIQSMANVSTMDTEAAVAQAIRMIEAGAEYVRFTAQGEREARNLGEIRKQLNEQGYTTPLVADIHFNPRAADAAAGEVEKVRINPGNYVDKVKTFSHLEYTDEEYAAEIEKIRERFVPFLNICKAHGTAIRIGVNHGSLSDRIMSRYGDTPEGMVASCMEFLRICREENFPDVVISIKASNTVVMVRTVRLLVRTMEAENMHYPLHLGVTEAGDGEDGRIKSAVGIGTLLCDGIGDTIRVSLSEDPEAEMPVARKLVDYIRERENHRPIEASMAPGFDTVATSRRISRVVEGIGGTFSPVVISDRSSGDFEFDYLSLPDYIYIGKEDPDNLPDNFRLLVDAHFWKERPNAFPCFIASEAEELKDYDCPLKFIRLTYMDLTDRMLEILKADKTVVVLLSTHHRNGVGSQRAAMHKLLMAGCDVPVVLHRDFRETDVELLQLKSAADFGTLLLDGFGDGLMLHNEGCEAVVSDRCMFGILQATRTRISKTEYISCPSCGRTLYDLQTTIARIKEATSHLKGLKIGIMGCIVNGPGEMADADYGYVGAGRGQISLYKGKECVLKNIPEEDAVERLVQLIKENGDWVN
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: UPPP_KINRD
Sequence: MSMGIVEGAFLGLVQGLTEFLPISSSGHLAVVGTLLGSDPGAAFTAICQLGTEAAVIGYFRKDIARIIGHWARSLVGRLPRNDPDARMGWLVTLGTIPIGVLGLLFQDSIETVLRGFVVIGTTLWLFALVLGAADRFGRKERTLDQLSWKHGLLFGLAQALALIPGVSRSGGTITMGLLLGYTREAAARYSFLLAIPAVVLSGFYQLYDELSRGTTIAWVPTAVATVVAFVVGYAVIAWLMRFISTHSYTPFVVYRIAAAVVVYALVLAGALPAFQGTGGS
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLMN_MACMU
Sequence: MEHKEVVLLLLLFLKSGQGEPLDDYVNTKGASLFSITKKQLGAGSIEECAAKCEEEEEFTCRSFQYHSKEQQCVIMAENRKSSIVFRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTRTGITCQKWSSTSPHRPTFSPATHPSEGLEENYCRNPDNDGQGPWCYTTDPEERFDYCDIPECEDECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDGEPRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGDVAVTVSGHTCHGWSAQTPHTHNRTPENFPCKNLDENYCRNPDGEKAPWCYTTNSQVRWEYCKIPSCESSPVSTEPLDPTAPPELTPVVQECYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHWHEKTPENFPNAGLTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEGSVAAPPPVAQLPDAETPSEEDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHSHRIFTPETNPRAGLEKNYCRNPDGDVGGPWCYTTNPRKLFDYCDVPQCAASSFDCGKPQVEPKKCPGRVVGGCVAYPHSWPWQISLRTRLGMHFCGGTLISPEWVLTAAHCLEKSSRPSFYKVILGAHREVHLEPHVQEIEVSKMFSEPARADIALLKLSSPAIITDKVIPACLPSPNYVVADRTECFITGWGETQGTYGAGLLKEARLPVIENKVCNRYEFLNGTVKTTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
What is the function of this protein?
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation.  In ovulation, weakens the walls of the Graafian follicle.  It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5.  Cleavage of fibronectin and laminin leads to cell detachment and apoptosis.  Also cleaves fibrin, thrombospondin and von Willebrand factor.  Its role in tissue remodeling and tumor invasion may be modulated by CSPG4.  Binds to cells (By similarity).
What are the official names of this protein?
Plasminogen.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasminogen subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface (By similarity).
Protein: RL32_AZOSB
Sequence: MAVQQNKKSPSKRGMHRAHDFLTAPSLAVEPTTGEVHLRHHISPNGFYRGKKVVKAKGE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NUOK_PSESM
Sequence: MNAIPLEHGLAVAGVLFCLGLVGLMVRRNILFVLMSLEIMMNAAALAFVVAGSRWAQPDGQVMFILVISLAAAEASIGLAILMQLYRRFHTLDIDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HISX_SYMTH
Sequence: MLKVWEPQAFLEFLNRRRTEFYPEIEAQVRAILERVRREGDGALYAFTRQFDGADLEATGLRVTEAEYREAEAAVSAAFRAALQVAVENIAAFHRPQVPTSWFTTRPDGTIVGQRVTPVDRAGVYVPGGSAPLFSCLLMTAIPAVVAGVPEVIVCTPPDRNGRIDPHMLVAARAAGVKDVYKVGGAQAIGAMAYGTATVPRVDKIAGPGNYYVTLAKKLVFGPVGIDMLAGPTEVMAVDDGSVDAEWLAADLLSQAEHPNGMVILVTTAGPERIAAVGAAMARHTAALPRAETIRRSVAELGAALAVDTLEEAADLVNAVGPEHLEVGVADPWAFLPLVRHAGSIFLGRWTPEAMGDYIAGPSNVIPTEGTARYASPVCVETFIKRSAVTCYSEAAFRAQAPHAVRLALTEDLLAHAASMQIRLAKPDGESPSEGREAG
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: SASH1_MOUSE
Sequence: MEEDAGAASPAPEPEPEVDPARELEPEAGVSESISRLWTDVMGILDGSLGNIDDLAQQYADYYNTCFSDVCERMEELRKRRVSQDLDVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKYPLHKSNSEDGCVGKGDWKKKNKYFWQNFRKNQKGIMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSSTLDPADWPDGSYPTLDGSSTCNSREQSDDETEDSVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSAEGGEEHVFENSPVQDERSALYSGVHKKPFFYDGSPEKPPEDDADSLTPSPSSSSLDTWGAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSNNSDPAGKEGDFVYKEVIKSPPAPRISLGKKVRSVKETMRKRMSKKYSSPVSEQDSGLDGMPSSPASGKPDSEHVDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLNEEEEKPKRPTRRRKKGRPSQPKSVEDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQSGSQEKLLVDNQGLSGRSPRDSGCYESSENLENAKTHKPSVLSTKSSTESNLKSFTRSQPGNYPTLPLMKSGEVRKQGEEGRLGRGLAPDTAKSCDVPSVTDLSKNRRSLPVSICRSCETLEGPEPVESWPRSHSLDDLQGDADVGKNVPTEMPETCSQNVPEVPQKTSACTSKALPRGRDPTADVMLLTQSKRFSDPPKTMAKKLDGSVVASNLGIAPPQCIPRDFEAQPPVKPGLTRTSLEGLRKGHDHHPLGTKEGVDGEQSAPETRTQSRHPSQPPPVPAKKSRERLANGLHLVPSPEAPILPLKKASPASPVSPSDCPSPREPRPSSGTEPGSPACTRPPPWLAELPESTSLQEHGVKLGPVLSRKVSCVRGVDLEMLTENKLQAEGIDLTEEPYSDKHGRCGIPEALVQRYAEDLEQPERDVATNMDQIRVKLLRKQHRMAIPSGGLTEICRKPLSPGCVASMSDWLISIGLPMYTSTLSDAGFSTLSQVPSLSHSCLQEAGITEERHIRKLITAARLFKLPPSPEAM
What is the function of this protein?
Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation.  It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation.  Regulates TRAF6 and MAP3K7 ubiquitination.  Involved in the regulation of cell mobility.  Regulates lipolysaccharide (LPS)-induced endothelial cell migration.  Is involved in the regulation of skin pigmentation through the control of melanocyte migration in the epidermis.
What are the official names of this protein?
SAM and SH3 domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_CHRSD
Sequence: MKTVTLSRLNAFKHAQEPFSCLTAYDASFAQHADAAGIDVLLVGDSLGMVLQGHASTLPVTLDDILYHTRCVARGKQRSLLMVDLPFMSNADTGQLLRDAGALMRAGAELVKIEGAGWMHEGVRELTRRGVPVCAHLGLTPQSVHQFGGYKVQGREQDDAQRIIDDARLLVEAGASVILLECVPAALGRAVRDAVDVPVIGIGAGPEVDGQILVMHDVIGVTHGRPPRFAKNFLAGRDSIQAAFEAYRDAVKTRQFPAEEHCF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BURPG_ORYSJ
Sequence: MATSFLFSLILLLITALSLPFPLHASSVDPLSAGATTVRYWNRKIPNNAPHPDFFLSLLSPLPASVSSSLSSPLSISPSICRSARLLCPNSTYFQSLSSTVFIDGCTFSYSCTFTYEHTNITIKPGIFFREQELKEGNVVRMPDIANELTTARSSFLPRSIADRIPFKAEAVKSLFGLEPNTTLAKAVDETVAQCQSSPSKGETKRCVTSAEDMIDFAVAMLGDDIVVRSTVLPNGPGESIMIGKVKGINGGKITSSVSCHEYLFPYMVYYCHSVPKIRVYEAEILSVQTKEKINSGVAICHIDTSAWNAGHPAFVALGGKPGQNKVCHWIFNGSMTWVIADKS
What are the official names of this protein?
BURP domain-containing protein 16, OsBURP16, Protein WGP1, OsWGP1.
Protein: SYDP_SHEB8
Sequence: MSCLPALDKFLQNYHQAYLTSLGELLRYYPQGEASVCIQGEFHADLDQAVSWQPVKREVEGSFANVEHALELTLWPEINHFYGQYFSAPLLFDSEWGTGELLQVWNEDDFTCLQQNLIGHLMMKKKLKQPPTWFIGLLDEGDKMLTINNSDGSVWIELPGEIPTQQLSPSLAEFIGALSPRIAPPVKHEELPMPALEHPGIFASFKRMWQNLFGKR
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: PK66_PLAKU
Sequence: MNKIYYILFLSAQCLVHMGKCERNQKTTRLTRSANNASLEKGPIIERSIRMSNPWKAFMEKYDLERAHNSGIRIDLGEDAEVGNSKYRIPAGKCPVFGKGIVIENSNVSFLTPVATGAQRLKEGGFAFPNADDHISPITIANLKERYKENADLMKLNDIALCKTHAASFVIAEDQNTSYRHPAVYDEKNKTCYMLYLSAQENMGPRYCSPDSQNKDAMFCFKPDKNENFDNLVYLSKNVSNDWENKCPRKNLGNAKFGLWVDGNCEEIPYVNEVEARSLRECNRIVFEASASDQPRQYEEELTDYEKIQEGFRQNNRDMIKSAFLPVGAFNSDNFKSKGRGYNWANFDSVNNKCYIFNTKPTCLINDKNFFATTALSHPQEVDNEFPCSIYKDEIEREIKKQSRNMNLYSVDKERIVLPRIFISTDKESIKCPCEPEHISNSTCNFYVCNCVEKRAEIKENNEVIIKEEFKEDYENPDGKHKKKMLLIIIGVTGAVCVVAVASLFYFRKKAQDDKYDKMDQAEAYGKTANTRKDEMLDPEASFWGEDKRASHTTPVLMEKPYY
What is the function of this protein?
Merozoite receptor PK66 is a surface antigen involved in parasite invasion of erythrocytes.
What are the official names of this protein?
Merozoite receptor PK66, 66 kDa protective minor surface antigen.
What is the protein family that this protein belongs to?
Belongs to the apicomplexan parasites AMA1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Note=Concentrated at the apical end prior to rupture, following which it can distribute itself entirely across the surface of the free merozoite. During invasion PK66 is excluded from the erythrocyte at, and behind, the invasion interface.
Protein: PLPL_MAGOY
Sequence: MTEKQINVPARAYGFPPDAYDPSLLPDFDVSFLRPEDLEAFIQALSAPDTTQPPDDGLASPRSPSARSFSSFDFTKRASSVLPDDAQVVAAHAAAAGGETAPIPGDNDTNNANGFGNSSSQSLFITAQSDWAPVHEKVVGSQTHRQKKSSRRRKRSKAVAPGRRTRDETREGYLYGLLKWPFLLIVGAWIVGLAVTYLFTRAYIFIYEQFVAWRGRREKLRRNMRATSRYPDWVKAARDLDNFLGNEAWKEQNEFAYYDSKTVRRVWDSLRRSRIRAAQMEASGSQSSSSSNEGKTTPIEDLKVLIEACVKNNFVGVENPRLYSQTYYGTKNLVQNYVDEVEKSLTALLETKQLSMEDKRSIFKRVSANYGRTALCLSGGASFAYYHFGVVKALLEEDLLPDVITGTSGGALVAALVATRTNEELKKLLVPSLSTKITACREPITVWFRRWWSTGARFDSVDWAKQCSWWSHGSMTFREAYERTGRILNVSCVPADPHSPTILCNYLTSPDCVIWSAVLASAAVPGILNPVVLMMKKADGNLAPYSFGHKWKDGSLRTDIPIRALNLQFNVNFTIVSQVNPHINLFFFSSRGSVGQPVTHRRGRGWRGGFLGSATEQYIKLDLTKWLKVLRQLELLPRPLGQDWSQLWLQQSFGGTVTIWPKTILSDFVHILSDPDNARLARMIHEGQQSTFPKIKFISNRLRIERLIERGRRETRPYIRRGSVESIISEDDLRELLLLRGSTNGTDEEITTNDEMEFASDEKAVLTEDEGQFDGVTDNTEGSPLLK
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein OOU_Y34scaffold00095g16.3.
What is the protein family that this protein belongs to?
Belongs to the PLPL family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: P3_RGDV
Sequence: MDVTGAPYSSGLNVRNVLLTESTSTFTPIETYNVQDDIRTIRISAKIAEESVVSRVPLPVSFKPISEITKLFDIIPISRGSTTSIVEHPQTSFMIKLRDNTFSDYACLDHLVAFEPALILHRLKMLFSILGKYASSIISEVPTLDVMIDNAQVTVIDMSKFDDRNMNTYADRLPRDIEVYAAKQDILKQYVRTSVNETPITFRDDLPMPVRERPTLYRRYIVPFTPVELSLYNMALQMLDLQYCHPLIVYKYLQDRAPPFLVVNDQIGLEMLSAGDGELLPRPVMEVLDYSLVYSSPLALNNLGSLLMSRIKTSIKVRSINEVSSSLSEIVNASSTVSNSASSAIANMNVAGVETIAAFIIRSVLNPNISYAMIGKLDLDAFNDFIYGTCLLLLQAITPPSAIAAMSRVRINNALAYFLLRYICPQPVYTRLLQNDVIPSLTNTLEWSSVDRDILAAIYSNLFVADGRIWNLVSRYYRELPPEEVTQVSVPARETSYGINETRGISLPYLFGDAITEMRPDNRLNDYKQRLNLPSRSPILIANPMRNNVVDLTNVNVKMDFIMDLYDQNNFLKSPAQWVRNSASNSALLAKFRDSVSNITGILENVLSNAYSNAVNTYCDSVYRAGVPLNWKYRVVIDPKDMMFVIFGVCPRYVLMGDSIPDFFAGSEDILILQLVRAIWEVMSNHMGNVPTRFFRMEDVQRDLSEMVSIVLSKKIDVTKYFTDDMRSTTFSKEAWERFIARQIGEELPPLYRTILDQVETINNYMEQMMSIMPIVDHFYVVRNSGIAARGSVNPILAATTLNLNQINTTMIIRDWSELVRLVMTQQRVDLNTSHSLFEAEFYKLSEIASNEFVRSNERGEAEPHFTDVEAIRINMYARYELKIYKEQGEFSKPTKLNKVMHEDLTSFVKSNIGKPYPPVFTIPIDIMLNDLGECTSTKTRMRSFKVDEYFKCFTGAQVIIPLDYVNLEHVGSIQDLQVMFNGSVSVRIKPWTIKENFDVNYVQTGNHEVLIDPLPNVLPI
What is the function of this protein?
Capsid protein which self-assembles to form the inner icosahedral capsid with a T=2 symmetry, and consisting of 60 P3 dimers.
What are the official names of this protein?
Outer capsid protein P3, Core protein P3.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus inner capsid protein P3 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Found in the interior of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: PDRP_ALKCK
Sequence: MTNDTERLVVYIVSDSVGETAELVVKAAVSQFSGSNVELRRIPYVEDKGTIQEVVQIARKAKALIAFTLVVPEIRDFLLESAKAANVETVDIIGPVLSKITDLTNAKPRYEPGLIYRLDEDYFRKVEAIEFAVKYDDGRDPRGIILADIVLIGVSRTSKTPLSQYLAHKRLKVANVPLVPEVEPPEELFKISSKKCIGLKISPEKLNSIRTERLKALGLKSEANYANIDRIKEELEYAKKVMDRVNCPVIDVSNKAVEETANLISSMFQRN
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: ACCA_HELPS
Sequence: MAIYLDFENHIKEIQNEIELALIRGDEDAKEILEKRLDKEVKSIYSNLTDFQKLQLARHPDRPYAMDYIDLILKDKYEVFGDRHYNDDKAIVCFIGKIDNVPVVVIGEEKGRGTKNKLLRNFGMPNPCGYRKALKMAKFAEKFNLPILMLVDTAGAYPGIGAEERGQSEAIAKNLQEFASLKVPTISVIIGEGGSGGALAIAVADKLAMMEYSIFSVISPEGCAAILWDDPSKTEVAIKAMKITPRDLKEAGLIDDIILEPSKGAHRDKFSAANTIKEYFLDALRTIQQDPHFLDNRYQKLMSLGSFVESMN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO11_HALSA
Sequence: MDLRVIEKDDAELTIEVAGENHTFMNVLKGTLLETDGVTAASYDMNPEQSGGQTEPLLTIKTDGDVDPVDALQAAAGHTSQKLQSFADTFEAAV
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP6_ROT41
Sequence: MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMLITMNGNEFQTGGIGNLPVRNWNFDFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCIDEMVRESQRNGIAPQSDSLRKLSGIKFKRINFDNSSEYIENWNLQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANTQQFEHVVQLRRVLTTATITLLPDAERFSFPRVVNSADGATTWYFNPVILRPNNVEVEFLLNGQIINTYQARFGTIIARNFDTIRLSFQLMRPPNMTPAVAALFPNAQPFEHHATVGLTLRIESAICESVLADASETMLANVTSVRQEYAIPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLVK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: VL1_HPV60
Sequence: MALWLQTAGQLYLPPSKPVARVLSTDEYVQPTNLVFHTGTDRMLIVGHPYFDIIDSGSNNITVPKCSGNQFRVMRLLFPDPNKFAMIDRAVFNPERERLVWRLEGLEIGRGGPLGIGTSGHPLFNKYGDTENPAAYPLKQNNGDDNRMDVSMDPKQMQLFIVGCKPATGEHWDIAKPCDPAPAKGSCPPIKLTQSIIQDGEMCDTGFGNANFITLQEDKSGVPLDITNEICKYPDLLKMTKDIYGDAVFFFGKREQIYSRHYFVRGGIDGDSLPDSGYYLAPQTDKPQNNLGGYSYFPTPSGSVASSDNQLFNRPYWLHRAQGANNGICWGNQLFITIVDNTRNTNLSISVYKQDAAIDNRYKYKQEDFRQYLRHTEEYEVELILRLCKVPLNPDVLAHLNVMDKNILEDWQLSFVPPPPQGIEDAYRYIMSQATMCPTDVPNTEREDPYKQYTFWTIDLQERFSNELSQFSLGKRYLYQYGLLNGRKRSASSFVTKKSKTVKRKRTK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.