PharMolix/UniProtQA huggingface dataset:
Protein: C1QL4_MOUSE
Sequence: MVLLLLVAIPLLVHSSRGPTHYEMLGRCRMVCDPHASRGQGPDGAPASVPSLPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPGPGPGGAAPPAGYVPRIAFYAGLRRPHEGYEVLRFDDVVTNVGNAYEAASGKFTCPMPGVYFFAYHVLMRGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVILHLDVGDEVFIKLDGGKVHGGNTNKYSTFSGFIIYPD
What is the function of this protein?
May regulate the number of excitatory synapses that are formed on hippocampus neurons.  Has no effect on inhibitory synapses.  May inhibit adipocyte differentiation at an early stage of the process.
What are the official names of this protein?
Complement C1q-like protein 4, C1q and tumor necrosis factor-related protein 11, C1q/TNF-related protein 11, C1qTNF11, CTRP11.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_YEAST
Sequence: MPLKRSLKESIERLSSFQSKYNIFTSINPSPYSITNKKGTKETLTGCVASIKDNIVTKDFPTTCASHILENFKSPFDATVVKLLKQAGVHILGKTNLDEFGMGSGGVHSIRGPVINPLYPHEDKKIMGGSSSGAAASVACDLVDFALGTDTGGSVRLPACYGSVLGFKPSYGRLSRFGVIAYSQSLDTVGILSKKINVLRKVFHTLDKYDMKDPTSLSVELRELIEGNKKVRRPLKVGIVKEFSHESMPIGFHRLYLSLLEKLINLGLEIYPVSIPSVKNCLPIYYTLSPAEAASNLSRYDGIRYGYRDSELDIKDGILFAPTRSKFGTEVKNRIILGNYNLCSDAFKNNFIKAEKLRVNLIDEFDGIFRFPNVLTNSKGNPDGLDLLIVPTSSKLPGSIRDFEEEEAKSPANSYINDVFTVPMSLAGLPSLSMPLKEKTPIGLQVVGQYGDDSTVLDFVESIS
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  Required for HMG2-induced ER-remodeling.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A, HMG2-induced ER-remodeling protein 2, Loss of respiratory capacity protein 6.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SDR_YARLI
Sequence: MPAPATYATGLTPLPTPVPKVSKNIMERFSLKGKVASITGSSSGIGFAVAEAFAQAGADVAIWYNSKPSDEKAEYLSKTYGVRSKAYKCAVTNAKQVETTIQTIEKDFGKIDIFIANAGIPWTAGPMIDVPNNEEWDKVVDLDLNGAYYCAKYAGQIFKKQGYGSFIFTASMSGHIVNIPQMQACYNAAKCAVLHLSRSLAVEWAGFARCNTVSPGYMATEISDFIPRDTKEKWWQLIPMGREGDPSELAGAYIYLASDASTYTTGADILVDGGYCCP
What is the function of this protein?
Versatile oxidoreductase that catalyzes the oxidation and reduction of polar as well as non-polar substrates at a very broad pH range.  Preferentially oxidizes secondary alcohols.  Has highest activity for racemic 2-heptanol and racemic octanol.  Is also an efficient reductase for selected substrates.  Substrate selectivity was found for medium chain length ketones with the carbonyl function at position C-2.  Has highest activities for ribulose and fructose.  The enzyme is (R)-selective in the reduction direction and produces exclusively the (R)-enantiomer.
What are the official names of this protein?
Probable NADP-dependent mannitol dehydrogenase, MtDH, Mannitol 2-dehydrogenase [NADP(+)], Short chain dehydrogenase/reductase, YlSDR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TBA1A_MOUSE
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1A chain, Alpha-tubulin 1, Alpha-tubulin isotype M-alpha-1, Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS7_LACJO
Sequence: MPRKGNIAKRDVLADPVYNSKLVTKLINHLMIDGKKAKASSILYDAFGIIQDKTGKEPVEVFEEAMNNVMPVLEVKARRIGGSNYQIPVEVRPERRTTLGLRWLVSYARLRNEHTMDERLANEIMDAANNTGSAVKKREDVHRMAEANRAFAHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL35_CHLAB
Sequence: MPKMKSNKSVAARFKLTGSGQLKRTRPGKRHKLSKKSSQEKRNLSKQPLVDKGQVGMYKRMMLV
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PURA_VEREI
Sequence: MTATKGRNVVVVGTQWGDEGKGKLVDWLTQSAQGVVRFQGGHNAGHTLVINGVKTALHLIPSGIMRPGVKCYIGNGVVLSAAKLFEEIEGLEKAGVEVRSRLRISEACPLILPFHAAIDIAREAAREQGGAEKIGTTGRGIGPAYEDKIARRALRVQDLKHPERFAARLRELLDLHNHLLTTYLGSATFVFDAALKPYIEAGKVQFDVVHAEAMRHAELLKPMMADVSRELNEAHRAGINLLFEGAQGTLLDVDHGTYPYVTSSNCVAGNAAAGSGVGPGMLHYILGITKAYCTRVGGGPFPTELDWQVPGTPGYHMSLVGAEKGVTTGRSRRCGWFDAALLKRSAQVNGLSGLCITKLDVLDGLAELRLCTGYELDGARIDLPPMGAEDIIRCRPIYETLPGWSESTVGVTDYAKLPQNARRYLERIEQVTGVPIDLISTSPDRDHTIMMRHPYDAG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_CHLTE
Sequence: MGQKVNPTGFRLGIIKDWTSRWYDDGPVIAEKIKQDQVIRNYVHARLKKEKAGIAKIVIERTTKHIKINIYAARPGAIVGHKGEEINNLSQELTRITGKEVKIDVIEVIKPEIEAQLIGENIAYQLENRVSFRRAMKMAIQQAMRAGAEGVRIRCAGRLGGAEIARAEQYKEGKIPLHTLRANVDYASVTAHTIAGAIGIKVWVYKGEVLVQRLDAIEEEEMKKMQERRGDSRGRGRGDGRGAKRRRRPAKKA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: CENPN_HUMAN
Sequence: MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQHLIHLCEEKRASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDMKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFKQYNQTFETHNSTTPLQERSLGLDINMDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSGLNGSILAEREEPLRCLIKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYFKIRDK
What is the function of this protein?
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.  CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly.  Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
What are the official names of this protein?
Centromere protein N, CENP-N, Interphase centromere complex protein 32.
What is the protein family that this protein belongs to?
Belongs to the CENP-N/CHL4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the kinetochore domain of centromeres. Kinetochore-bound levels decrease when cells enter mitosis and increase again when cells exit mitosis.
Protein: PAFA_ACTMD
Sequence: MQRRIFGIETEFGVTCTFHGQRRLSPDEVARYLFRRVVSWGRSSNVFLRNGSRLYLDVGSHPEYATAECDDLAQLVSHDKAGERILEDLLVDAERRLADEGIGGDIFLFKNNTDSAGNSYGCHENYLVARAGEFSRIADVLLPFLVTRQLICGAGKVLQTPRGAVYCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAERYRRLHVIVGDSNMSEVTTLLKVGSANLVLEMIEQGVQFRDFSLDNPIRAIREISHDLTGRRTVKLAGGKEASALDIQREYYERAVEHVAKRSPDPMAERVLELWGRTLDAIAAQDLSKIDREIDWAIKHRLLERYQAKHDMDLSNPRIAQLDLAYHDIRRGRGVFDLLQRKGQVERVTDDGEIEAAKDTPPQTTRAKLRGDFIAAAQAAGRDFTVDWVHLKLNDQAQRTVLCKDPFRAVDERVERLIASL
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: RECF_YERPE
Sequence: MALTRLLIKDFRNIESADLALAAGFNFLVGPNGSGKTSVLEAVYTLGHGRAFRSLQAGRVIRHECAEFVLHGRVDANEREASVGLSKSRQGDTKVRIDGTDGHKVAELAQMLPMQLITPEGFTLLNGGPKFRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVSRYTQIRAWDQEIIPLAERISEWRAAYSDAIAADISATCALFLPEFALSFSFQRGWDKESDYGELLARQFERDRALTYTAVGPHKADFRIRADGTPVEDLLSRGQLKLLMCALRLAQGEFLTRQSGRRCLYLLDDFASELDTGRRRLLAERLKATQAQVFVSAVSAEQVADMVGEKGKMFRVEHGKIEVQPQD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S1CC_NAJAT
Sequence: MKTLLLTLLVVTIVCLDLGYTLECHNQQSSQTPTTKTCSGETNCYKKWWSDHRGTIIERGCGCPKVKPGVNLNCCTTDRCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.  Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site.  Has a lower toxicity than cobrotoxin.
What are the official names of this protein?
Cobrotoxin-b, CBT-b, Atratoxin-b, Cobrotoxin III, CBT-III, Cobrotoxin IV, CBT IV, NT3, Short neurotoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOD_CAUSK
Sequence: MTGSNSPAAATDFFHDAPSLPAVPETPVRKFNINFGPQHPAAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLMEARTYLQNIPYFDRLDYVAPMNQEHAFCLAIEKLLGVDVPLRGSLIRVLFCEIGRVLNHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERACGARLHANYFRPGGVHQDLTPSLIDDIEKWAKAFPKICDDIEGLITDNRIFKQRNVDIGVVTKEDALAWGFSGVMVRGSGIAWDLRRNQPYECYNDFEFDIPLGKNGDCYDRYLCRMQEMRESTKIILQAIEKLRATPGPVMTQDNKVAPPRRAEMKRSMEALIHHFKLYTEGFRTPEGEVYACVEAPKGEFGVFLVSNGTNKPYRCKIKAPGFSHLAAMDWMNRGHQLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LPTD_ACTPJ
Sequence: MKTRYSVLSVAMTAAFYTQYAQADLREQCLLGVPHFQGEEVTGDQTMMPIEIEADNAVINQPKDATYTGDVAIKQGNRSLFADEVRVEQNGEQERRAFLKGSYRYQDNLVQAHGRDAAMDLGSETAELQNTEFQLVGRQGRGTAESGLFNHNKRILKNATFTACLPNDNAWSIEGNEMIQHIDEEYAEIWHARFKVLGMPVFYSPYLQFPIGDRRRSGLLIPNFHRSSKDGFAYSQPFYWNIAPNMDATITPTYYSRRGWQISPEYRYLTKLGEGIVAGEYIGKDRLDEYRPDDNDRKRYLMHWRHNMSFLTGWRLYVDYTKVSDKRYFSDFDSEYGSSTDGYATQQFKLGYYQPNYNLSISGKKFQTFDELDVGPYRVLPQIDFNYYNDELVKGGDFKLFAQTARFENDSKLMPKAWRFHVEPTLNFPLANRYGSLNFETKLYATHYLQEKGSSKQADDMDKNVTRIIPQVKVDLQTVLEADKQLFKGFNQTFEPRVQYVYRPYKDQSNIGSGLNQSVSFGYDSALLQSDYFSLFNDRRYSGLDRISSANLITAGGTNRFFNEKTGVEVFNFSIGQTYYLSPSKIDDLSQNSTTKRSSSWALESNWKFHRKWNWHGAYQYDTRLNQTSLANTSLQYKPSQDKLVQLSYRFASKDYINQNLRSNTYGQDIKQVGAVVGWELTDRVAFMASHYHDIALKKPVESQLSVNYNTCCWSANVYVARKLTATPIGSPDTINDLYYDNKFGVNFELRFGTNYSSGVRKMLKKGMIPYTEQYGIN
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS20_YERPY
Sequence: MANIKSAKKRAVQSEKRRKHNASRRSMVRTFIKKVYAAIAAGDKDAAQKAFNEMQPIVDRQSCKGLIHKNKAARHKSNLVAQINAMQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HXNT_EMENI
Sequence: MGSLSPLEPLFTPLRIGAFALQHRVVQAPCTRMRSTKESDGIWVPNDLNVEYYAQRASKGGLMLSEATPISRDAAGYPGVPGIFTPSQIEGWRKVTNAVHTKGGLILCQLWHVGRATTPGFLGGKTPLAPSDIPISGKALDGNVYADAPPRPMTVDEIKEVVLEYAAASKRAIEAGFDGVEIHGGNGYLLDQFLHDNVNNRTDAYGGSIENRSRIVLEIISAVTEAIGAERVGIRLSPYNYFQDTRDSNPQKHWGYLCTQIASLPESSRPAYVHMIEPRFDEILDESEKISALETMQEVVKPSLDGLRSSLKKGGVSFIAAGNFKPENAGEKLITDSADAIAFGRLFISNPDLPRRLKEGIELTKYDRSTFYGATPPEKGYTDYPFAQ
What is the function of this protein?
Flavin oxidoreductase, part of the hnx cluster involved in the purine degradation (PubMed:29212709).  The nicotinate hydroxylase hnxS accepts nicotinate as a substrate and catalyzes the first step of nicotinate catabolism (PubMed:29212709).  The major facilitator-type transporters hxnP and hxnZ are probably involved in the uptake of nicotinate-derived metabolites, and the oxidoreductases hxnT and hxnY in the further metabolism of 6-OH nicotinic acid (PubMed:29212709).
What are the official names of this protein?
Flavin oxidoreductase hxnT, Nicotinate catabolism cluster protein hxnS.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Protein: REX_CHLAD
Sequence: MERSDQPPDVVIRRLPLYARSLRYLLEEGIHSVSSQELGERINVTAAQIRKDLSYFGEFGKQGIGYDVEKLLHHIERILGLNQHWPVVLVGIGLLGQAIARYEGFRSEGIEIVALFDSDPAKIGQRVGDLVIQDFANVRRVVAEKQVKLAIIAVPALQAQRVADVLIEAGVRAILSYAPMILQVPEDVWVRYIDPVAVLQSMTYYLAREQQH
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF196_ASFB7
Sequence: MLFRYLVWLFRFIEVKNVVSISLLVIGSNYLTTAISNNTSTTISPTTSSNYLLTAISNNTSTTILPTTTSSNYLTSAIPNIISDKEDDTPFSTDKTVSDGLSPITLYRAIRSTLNDTMTDILTRPYRPTTVIFHSDTPQPVKNATQGNIIKKTYRQVLTFFIQPNPLFPCFKNHEVFLNLANILNTILCIILIKNV
What are the official names of this protein?
Late protein I196L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus I196L family.
Protein: HIS2_GEOSL
Sequence: MNERDDILQAVYEVILDRKGALPESSYTASLFHKGIDKILKKVGEEATEVIIAGKGGKREEIVYETADLLFHTLVLLGHYDIAPADVYNELRRRFGTSGHAEKASRNE
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRPB_SYNE7
Sequence: MNVIFLPQGDWLGLSFRLLLAMLVGAVIGLNRQRGGRPAGMRTFTLVAMGSALFVMVPIQAEGDSSFAAINALSRTVQGVAAGVGFLGAGLILQRAPKTKRSGRPRVSGLTTAATIWITAALGAVIGCGLWQLGLIGTFFTLLTLSGFKRLQRIAWLRQSWERLIAWEAKTLPPDAEEEDDD
What are the official names of this protein?
Protein SrpB.
What is the protein family that this protein belongs to?
Belongs to the MgtC/SapB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VM3AD_AGKCL
Sequence: MIQVLLVTLCLAVFPYQGSSIILESGNVNDYEVVYPRKVTVLPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKQLFSKDYSETHYSPDGREITTYPLVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGEMYLIDPLKLPDSEAHAVFKYENVEKEDEAPKMCGVTQNWESYEPIKKASQLNLTPEQQAYLDAKKYVEFVVVLDHGMYTKYKDNLDKIKTRIFEIVNTMNEMFIPLNIRVALICLEIWSDKDKFNMTSAANVTSISFRNWRATDLLKRKSHDNAQLLTVIDFDGPTIGKAYMASMCDPKRSVGIIQDHSTINLMMAVTMAHEMGHNLGMDHDEKYCTCGAKSCVMAKALSRQPSKLFSNCSQEDYRKYLIKRRPKCILNEPNGTDIVSPPVCGNELLEVGEECDCGSPTNCQNPCCDAATCKLTPGSQCADGVCCDQCRFTRAGTECRQAKDDCDMADLCTGQSAECPTDRFQRNGHPCLNDNGYCYNRTCPTLKNQCIYFFGPNAAVAKDSCFKGNQKSNNHTYCRKENGKKIPCAPQDIKCGRLYCFRNLPGKKNICSVIYTPTDEDIGMVLPGTKCEDGKVCSNGHCVDVNIAYKSTTGFSQI
What is the function of this protein?
Is a potent activator of prothrombin (F2).  Does not elicit any hemorrhagic response.  Barely inhibits collagen-induced platelet aggregation.  Binds neither collagen, nor the jararhagin-monoclonal antibody MAJar3.  Hydrolyzes the Aalpha-chain of fibrin and fibrinogen, without affecting the Bbeta- and gamma-chains.  Is capable of triggering endothelial pro-inflammatory and procoagulant cell responses, but fails to trigger apoptosis.  Induces von Willebrand factor release, and the expression of both ICAM1 and E-selectin (SELE) (without increase in VCAM1) in endothelial cells (HUVEC).  Is also able to up-regulate the synthesis of the coagulation factor TF (F3).  Enhances nitric oxide (NO) generation, prostacyclin production and interleukin-8 release (By similarity).
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like ACLD, Snake venom metalloproteinase, SVMP, VMP-III, AclVMP-III.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_SLCV
Sequence: MVKRDAPWRLMAGTSKVSRSANFSPREGMGPKFNKAAAWVNRPMYRKPRIYRTMRGPDIPKGCEGPCKVQSYEQRHDISHLGKVMCISDVTRGNGITHRVGKRFCVKSVYILGKIWMDENIKLKNHTNSVMFWLVRDRRPYGTPMDFGQVFNMFDNEPSTATIKNDLRDRYQVMHRFYAKVTGGQYASNEQALVRRFWKVNNHVVYNHQEAGKYENHTENALLLYMACTHASNPVYATLKIRIYFYDSITN
What is the function of this protein?
Encapsidates the viral DNA into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  The CP of bipartite geminiviruses is not required for cell-to-cell or systemic movement.
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).
Protein: AROC_PARXL
Sequence: MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGLALNEADIQLELDRRKPGTSRHVTQRQEEDKVEILSGVFEGQTTGAPIALLIRNTDQRSKDYGNIADTFRPGHADYTYWQKYGIRDYRGGGRSSARLTAPTVAAGAVAKKWLREKFGTEIRGYMAALGEIDVPFVDWAHVRENPFFVPNQQIVPQLEAYMDALRKEGDSIGARINVVASGVPVGLGEPLFDRLDADIAHAMMGINAVKGVEIGAGFASVAQRGSVHGDELTPEGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSIDKAGQPAVVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVSVSTPKIAASAP
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: Y4PD_SINFN
Sequence: MNQPRLASGQRNLELTSRVVSAYLSRNIVPAADLASLIQQTYLSLCSTSQADKAEEAAVEEQRPAVPIKKSVTADFIICLEDGKKFKSLKRHLMAKYGLTPQQYREKWGLPADYPMVASSYAQKRSELARALGLGKKRTAPELGSGLVNHSQKMTEAAMQIAEKKVWAHRS
What are the official names of this protein?
Putative MucR family transcriptional regulatory protein y4pD.
What is the protein family that this protein belongs to?
Belongs to the ros/MucR family.
Protein: EFG_CORDI
Sequence: MLKDLNKVRNIGIMAHIDAGKTTTTERILFYTGINRKVGETHDGASTTDWMEQEKERGITITSAAVTCFWNGNQVNIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQAAKYDVPRICFVNKMDKLGADFYFTVQTIIDRLGAKPLVMQLPIGAEDDFDGVVDLLEMKAITWRGKVETGAEPVIEEIPADLADKAAEYREKLVETVAESDEALMEKYFGGEELTIEELKAGIRKLTVNSEVYPVLCGTAYRNKGVQPLLDAVIDYLPTPLDIGEVHGHKVGDETVDLVRKPSVDEPFSALAFKIAAHPFFGKLTFVRVYSGIVEPGAQVANSTKGKNERIGKLFQMHANKENPVDEARAGNIYAFIGLKDTTTGDTLCDKNDQIILESMDFPDPVIKVSIEPKTKSDQEKLGTAIQKLSEEDPTFTVELDEESGQTVIGGMGELHLDVLVDRMKREFKVEANVGNPQVAYRETIRKPVEKLEYTHKKQTGGSGQFAKVIIGIEPYAPEAETLEEGESATYKFENAVTGGRVPKEYIPSVDAGIQDAMQYGYLAGFPLVNIKATLIDGAYHEVDSSEMAFKLAGSQALKEAVAKAKPVLLEPLMAVEVITPEEYMGDVIGDINSRRGQVSAMDDRAGAKVVKAKVPLSEMFGYVGDLRSRTQGRANYTMIFDSYAEVPTNVAAEIVAERNGTA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1273_LATSS
Sequence: MNIGIGVLIFVIGALLGAVAGFFGARAYMKKYFEENPPVNEDMLKAMMMQMGQKPSEKKLNQMMSSMKAQQKRSKK
What are the official names of this protein?
UPF0154 protein LCA_1273.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HMB3_TRIGR
Sequence: FERGWDISGWSSYYSCTYFHVSYLADGKRGRQTYTRQQTLELEKEFHFSRYVTRRRRFEIAQSLGLSERQIKIWFQNRRMKWKREHGSNCTMTNQQDQMPSMADFIGS
What are the official names of this protein?
Homeobox protein HB3.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.