PharMolix/UniProtQA huggingface dataset:
Protein: SPT6_CANAL
Sequence: MMKKKISAKKKNQQQQQLHQPTMSEVTEEERTRYEEEEDVRDSPSDSSEESEDDEEEIQKVREGFIVDDEEDEVQTKKRKSHKRKRDKERPHYDDALDDDDLELLLENSGLKRGSSSSGKFKRLKRKQIEDDEDEIESQDHQGEQQLRDIFSDDEEVEEEAAPRIMDEFDGFIEEDDFSDEDEQTRLERREQRKKKKQGPRIDTSNLSNVDRQSLSELFEVFGDGNEYDWALEAQELEDAGAIDKEEPASLDEVFEHSELKERMLTEEDNLIRIIDVPERYQMYRSALTYIDLDDEELELEKTWVANTLLKEKKAFLRDDWVEPFKQCVGQVVQFVSKENLEVPFIWNHRRDYLEYVDPDAPIPGSVRELMISEDDVWRIVKLDIEYHSLYEKRLNTEKIIDSLEIDDELVKDIKTLDSMVAIQDMHDYIQFTYSKEIRQREETQNRKHSKFALYERIRENVLYDAVKAYGITAKEFGENVQDQSSKGFEVPYRIHATDDPWESPDDMIERLIQDDEVIFRDEKTARDAVRRTFADEIFYNPKIRHEVRSTYKLYASISVAVTEKGRASIDAHSPFADIKYAINRSPADLIAKPDVLLRMLEAERLGLVVIKVETKDFANWFDCLFNCLKSDGFSDISEKWNQERQAVLRTAISRLCAVVALNTKEDLRRECERLIASKVRHGLLAKIEQAPFTPYGFDIGSKANVLALTFGKGDYDSAVVGVYIKHDGKVSRFFKSTENPSRNRETEDAFKGQLKQFFDEDETPDVVVVSGYNANTKRLHDVVYNFVSEYGISVKSEFDDGSSQLVKVIWGQDETARLYQNSERAKKEFPDKPTLVKYAISLGRYLQDPLLEYITLGDDILSLTFHEHQKLISNDLVKEVVESAFVDLVNAVGVDINESVRDSRLAQTLKYVGGLGPRKASGMLRNIAQKLGSVLTTRSQLIEYELTTRTIFINCSAALKISLNKSINVKDFEIEILDTTRIHPEDYQLAMKMAADALDMDEESELHEKGGVIKELLENDPSKLNLLNLNDFANQIYKLTHKLKFRSLQAIRLELIQGFAEIRSPFRILTNEDAFFILTGEKPQMLKNTVIPATITKVTKNHHDPYARIRGLKVVTPSLIQGTIDENAIPRDAEYVQGQVVQAVVLELYTDTFAAVLSLRREDISRAMKGGVVREYGKWDYKAEDEDIKREKAKENAKLAKTRNIQHPFYRNFNYKQAEEYLAPQNVGDYVIRPSSKGASYLTITWKVGNNLFQHLLVEERSRGRFKEYIVDGKTYEDLDQLAFQHIQVIAKNVTDMVRHPKFREGTLSVVHEWLESYTRANPKSSAYVFCYDHKSPGNFLLLFKVNVSAKVVTWHVKTEVGGYELRSSVYPNMLSLCNGFKQAVKMSSQQTKSYNTGYY
What is the function of this protein?
Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters.  Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT6, Chromatin elongation factor SPT6.
What is the protein family that this protein belongs to?
Belongs to the SPT6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFP_CORU7
Sequence: MATTADFKNGMVLMIDGKLQQIVEFQHVKPGKGPAFVRTKLKDVVSGKTVDKTFNAGVKVEQATVDRRDMTYLYNDGSAYVLMDDKTFEQVELQPELMGDGAKFLLENSRVNVSFHDGQALFAELPANVDLKIEHTDPGLQGDRSTGGSKPATLETGAEIQVPLFIETGNVVKVDTRTGEYLSRVTQ
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRA_STAES
Sequence: MAELPQSRINERNITSEMRESFLDYAMSVIVSRALPDVRDGLKPVHRRILYGLNEQGMTPDKPYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLVNGAAGIAVGMATNIPPHNLTEVIDGVLSLSKNPDITINELMEDIQGPDFPTAGLVLGKSGIRRAYETGRGSIQMRSRAEIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALIHYLEHQKTVVRRRTEYNLKKARDRAHILEGLRIALDHIDEIITTIRESDTDKIAMASLQERFKLTERQAQAILDMRLRRLTGLERDKIESEYNELLEYIKELEEILADEEVLLQLVRDELTEIKERFGDERRTEIQLGGLEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRSQNRGGRGIQGMNTLDEDFVSQLVTMSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPIINAIELENDETISTMIAVKDLESEEDYLVFATKQGIVKRSSLSNFSRINKNGKIAINFKEDDELIAVRLTTGNEDILIGTAHASLIRFSESTLRPLGRTAAGVKGISLREGDTVVGLDVADSESEDEVLVVTENGYGKRTPVSEYRLSNRGGKGIKTATITERNGNIVCITTVTGEEDLMVVTNAGVIIRLDVHDISQNGRAAQGVRLMKLGDGQFVSTVAKVNEEDDNEENADEAQQSTTTETADVEEVVDDQTPGNAIHTEGDAEMESVESPENDDRIDIRQDFMDRVNEDIESASDNEEDSDE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAG_CHRSD
Sequence: MSELVEHIQVHVEPEYQAGESAPGDQRYVFSYTITVHNRSAHSIQLLARHWKITQSSGKVQEVRGKGVIGQQPLIGPGQQFRYTSRAVLDGPVGVMEGSYTCLDTTEQRAFEVPIAAFRLAGPNQVH
What are the official names of this protein?
Protein ApaG.
Protein: LOLC_ECOLI
Sequence: MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVVLQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGDQIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGNITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGALLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQPAEALRYE
What is the function of this protein?
Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane.  Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA.
What are the official names of this protein?
Lipoprotein-releasing system transmembrane protein LolC.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU4M_PARLI
Sequence: MMITLILFTTGIVMTTLVIPQNKLWANAISQSALLSLSSPLLIFSNHWSAPWHNLSNILASDSISAPLIALSCWLAPISLIASNNTISKQSELNQRTFIIIVIFIAGALIITFSALELLLFYVAFETTLIPTLILITRWGAQMERFQAGLYFMFYTLFGSLPLLISLIAIYISSSSLSIPNVELIWTPSETMETLNIWWALSIIAFLIKMPIYGFHLWLPKAHVEAPVAGSMILAAILLKLGGYGLIRLINLFATISLNSLSLALITFCSWGALVTSIICVRQTDLKALIAYSSVGHMSIVAAAIFSSTNWGTNGALILMIAYGLVSSDLFSLANTVYERSGTRTLAITRGLKTILPLSTLWWLVMSAANLGLPPSPNLIGEILILSSLIAWSIWLFPIIGLATIFGAIYSLMIFQLSQQGTPTNNINNISLSFSREHLLATLHTLPLILIIINPISALITWLK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: WOR1_CANAL
Sequence: MSNSSIVPTYNGYIHNTRDALAVIQQVLDKQLEPVSRRPHERERGVLIVSGSVFVFIEQSSGIKRWTDGISWSPSRIQGRFLVYGELDKKNLIDKDKKKKKKRKFGPDDEYDHNVNEPDYTGGYGNHLHNDNRSHLNKNSRSGPMLLATGTGSITHTVIENKPSSSASMIHSNVIPASSSFLTDYRTSLGNGPMVSAAISQNGLVKKTITLTTTTKELHMEGKAEKQTIHLISYYSKQDIDSGKLQRPSESDLKHVQISPALWTMVQENSLGGKAPIDDEECFIVDGHNQYTNVSYIQQQQQQHQLQHQPLLHHSSSVAGSTTSIVNNSLSISNGGYGNNYSKNLSRSYNKYSNSQVSQLSYMLPPQTESSSTATIASGASVSVKREDDTNNGSNAPTGNENQYVNAINHSHTSSYGGQGYATDATGIATPAYNSYSQANTSINTSSQQQQQLQQGQYGQYVQYGVAPSTISGATSTNNNSGNAPNIPQDVYYSHYTGFVQPHYPQYHIATGNASDQYNTNAANHQYHSNNTTSSANNNSSSRTTGVGSKRKPSIVSNSTSGSVSGGNGNGNNYGYNSNSSTSTNRPPAVSTNTTSTTSGGSSFSGPSSNITTNSMSNNPWFNSSTNMAVNSSYITSSGGGNSHGGIGNNEYEPMPMTNNSASIPAYYQQHVPSHVGSAQQHQSQQQVAGVGAPHIIHNHPYLHPTYGQGSNSASTGDNSTPGGSSGSGSGGSGNNGAGGSSSVAATSGVTSSNTSGNIVTNGTLVAAGTDDAVGNSSGSYYTGT
What is the function of this protein?
Master transcriptional regulator of the switch between 2 heritable states, the white and opaque states.  These 2 cell types differ in many characteristics, including cell structure, mating competence, and virulence.  Each state is heritable for many generations, and switching between states occurs stochastically, at low frequency.  WOR1 Binds the intergenic regions upstream of the genes encoding three additional transcriptional regulators of white-opaque switching, CZF1, EFG1, and WOR2.  Phenotypic switching from the white to the opaque phase is a necessary step for mating.  Plays a role in cell adhesion and pseudohyphal growth.
What are the official names of this protein?
White-opaque regulator 1.
What is the protein family that this protein belongs to?
Belongs to the MIT1/WOR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLCB4_HUMAN
Sequence: MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.  This form has a role in retina signal transduction.
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4, Phosphoinositide phospholipase C-beta-4, Phospholipase C-beta-4, PLC-beta-4.
Protein: RS5_COXBU
Sequence: MQEAGIGTTTDGIQEKLVAVRRTAKVVKGGRVFGFSALVVAGDGDGKVGFGLGKAREVPSAIQKATENARRNMISVPLYGATLHHAIKATHASSTVLMLPASEGTGVIAGNAMRAIFEVMGVQNVLAKCIGSSNPINVVRATFKGLKQMETPESVAAKRGKAIEEIVE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RL30_STRZJ
Sequence: MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIRGMITAVSHLVTVEEVN
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TLCE_RICBR
Sequence: MLSTSSSRPFKSKFRAAFWPIYNYELGKFIPMSALMFCILFNQNILRILKDSILISEISAEIAGFAKVYCVTPAAALFVIIYAKMINHLTFEKIFYYLTAFFIGFFVLFAFVIYPNIHIFHVHPDYLADWMERYPHFKWYISLIGNWGYIVYYSLAELWPNIFYVLLFWQFANELTTTEEAKRFYTLFSLFGNSSLILVGFLMMNLSSKETIVKHFINISDSKITLVQISTILVTIVAVICCLLIRFISRNVFTNPLFYAKAKSGRSTSERMGIIKSFKYIVKSKYLWLLLICSAAFGFAINLVEAVWKAKIKELYPTVNTYAEFNSLYILWTGVAIMVMTIIGNNVMRMHNWFVAAVISPVIIMVTGVLFFVLIVFDQKILSLFDGAILMSPLALAVSIGGIQNILAKGTKYSIWDTSREMLYIPLDQELKTKGKAAVDVISAKVGKSSSGLVQSIIFTIIPTATFTSISPVLMVVFTFVCLAWIYAVRKIYFEYQKIA
What is the function of this protein?
Provides the rickettsial cell with host ATP in exchange for rickettsial ADP.  This is an obligate exchange system.  This energy acquiring activity is an important component of rickettsial parasitism (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein 5, ADP/ATP translocase 5.
What is the protein family that this protein belongs to?
Belongs to the ADP/ATP translocase tlc family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PROA_ANADE
Sequence: MRKEKSLGLAAEMRKLAEASREAARALSHADPRRKDAALRAAAEAIGRRERRILSENARDVAAARAAGQNAAYLDRLKLDPKRLAGIAASLREIAGLRDPVGEVTASWRRPNGLEIRKVRIPLGVVLMVYEARPNVTVDAAALCLKSGNAAILRPGSDALRSSLALAEAFAEGLEKAGLPAASAQVVPTPDREATYELLALDDLIDLAIPRGGPSLIRAVAERSRVPVLKHYQGVCHLYLDASAPPQQAVDLALNGKVQRPGVCNATECLLVHRAAAGKLLPPVGRALADAGVELRCDPTALTILKRAGVAAVPARPDDFGKEFLDKILAVRVVADLDGALDHIARYGSLHTEAIVTRDLASARRFQREVDASAVMVNASTRFNDGGELGLGAEIGISTTKLHAFGPMGLAELTTQKFLVEGEGHVR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_TOML
Sequence: MALVVKGKVNINEFIDLSKSEKLLPSMFTPVKSVMVSKVDKIMVHENESLSEVNLLKGVKLIEGGYVCLVGLVVSGEWNLPDNCRGGVSVCMVDKRMERADEATLGSYYTAAAKKRFQFKVVPNYGITTKDAEKNIWQVLVNIKNVKMSAGYCPLSLEFVSVCIVYKNNIKLGLREKVTSVNDGGPMELSEEVVDEFMENVPMSVRLAKFRTKSSKRGPKNNNNLGKGRSGGRPKPKSFDEVEKEFDNLIEDEAETSVADSDSY
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Forms a ribonucleoprotein complex with viral RNA.  Binds microtubules and modulates microtubule stability.  Can bind double-stranded DNA.  Triggers host hypersensitive defense reaction in incompatible plants harboring resistance (R) proteins.
What are the official names of this protein?
Movement protein, 30 kDa protein, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus movement protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton. Host cell junction, host plasmodesma. Note=Binds to the host cytoskeleton before being transported to the host plasmodesmata (Probable). Observed in virus replication complexes (VRCs) of tobamovirus infected host cells (PubMed:23148080). In resistant plants, targeted to the host plasma membrane via the interaction with host resistance (R) protein TM-2.
Protein: CHH1_MACRS
Sequence: AILDQSCKGIFDRELFKKLDRVCDDCYNLYRKPYVAIDCRRGCYQNLVFRQCIQDLQLMDDLDEYANAVQV
What is the function of this protein?
Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level.  Has a secretagogue action over the amylase released from the midgut gland.  May act as a stress hormone and may be involved in the control of molting and reproduction.
What are the official names of this protein?
Crustacean hyperglycemic hormone isoform 1, Crustacean hyperglycemic hormone isoform I, MAR-CHH-I, CHH I.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: DXR_VIBPA
Sequence: MQKLTILGATGSIGASTLKVVEQNPELFSVVALAAGTNVEKMVALCRQWQPKFAVMADKAAAVALQSEIHTISPNTEVLGGVDALCHVASLEEVDSVMAAIVGAAGLLPTMAAVKAGKRVLLANKEALVMSGQLFIDAVEQYGAELLPVDSEHNAIFQCLPQQVQTNLGRCNLDEHGISSILLTGSGGPFRYADIADLDSVTPAQAIAHPNWSMGPKISVDSATMMNKGLEYIEAKWLFNAARDQLKVIIHPQSVIHSMVQYRDGSVLAQMGEPDMATPIALTMSYPSRVDAGVKPLDFTQVGELTFLQPDFARYPCLKLAIDACYEGQHATTALNAANEVAVDAFLNNRLGFTDIARINELVLHKITASCKPENANSLESLLELDRMSRTIALEIIRERS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ENY2_AEDAE
Sequence: MTFTKSVDQTTILQGDRSKLKDLLRLRLNACGWSDQVRLLCREAIKEQDSINCDALVQQVTPKARALIPDTVKKELLQKIKTILVQQEGIDI
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histones.  The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (By similarity).
What are the official names of this protein?
Enhancer of yellow 2 transcription factor.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: SFXN3_MOUSE
Sequence: MGDLPLNINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGEQLEASRNIVQNYRAGVATPGLTEDQLWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRSGDAPITVQQLGTAYVSATTGAVATALGLKSLTKHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPVTDEAGQRLGHSVTAAKQGIFQVVISRIGMAIPAMAIPPVIMNTLEKKDFLKRRPWLGAPLQVGLVGFCLVFATPLCCALFPQRSSIHVTRLEPELRAQIQAQNPSIDVVYYNKGL
What is the function of this protein?
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway.  Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors.
What are the official names of this protein?
Sideroflexin-3.
What is the protein family that this protein belongs to?
Belongs to the sideroflexin family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: AIM11_YEAST
Sequence: MIEEKKELKKRRVLQMARFYGAAAFTLITMRLISRAIKVRKYVPSIFQQNYKLPPFSQRNEAMSALTYASAASIGTFSTLIFGFCWALDISTAREFVFKTREFMSLPQALETDTSMDEETSKLTKQLQDLLSSENNK
What are the official names of this protein?
Altered inheritance of mitochondria protein 11, Genetic interactor of prohibitins 8.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NMS_BOMMX
Sequence: MRSEKHLLPLPLLLAICCLGTLHLSSGFPQSVPSYLEGLDIPESERHAFCFSQWTALQDQEQIPSFVMDLCSSIYNRMKVNEENNHEIYKRFLFQFSRAKDPSLKIGESQIATAEYTKRDSSGIVGRPFFLFRPRNGRKVSINEH
What is the function of this protein?
Stimulates uterine smooth muscle contraction (EC(50)=1. 6 nM).  Synthetic peptide NmS-17 induces calcium mobilization in CHO cells transfected with either human FM-3/GPR66 (EC(50)=0. 085 nM) or FM-4/TGR-1 (EC(50)=0. 231 nM) NmU/NmS receptors.
What are the official names of this protein?
Neuromedin-S, Neuromedin-U.
What is the protein family that this protein belongs to?
Belongs to the NmU family.
What are the subcellular locations of this protein?
Secreted.
Protein: OR9K2_HUMAN
Sequence: MLGSKPRVHLYILPCASQQVSTMGDRGTSNHSEMTDFILAGFRVRPELHILLFLLFLFVYAMILLGNVGMMTIIMTDPRLNTPMYFFLGNLSFIDLFYSSVIEPKAMINFWSENKSISFAGCVAQLFLFALLIVTEGFLLAAMAYDRFIAICNPLLYSVQMSTRLCTQLVAGSYFCGCISSVIQTSMTFTLSFCASRAVDHFYCDSRPLQRLSCSDLFIHRMISFSLSCIIILPTIIVIIVSYMYIVSTVLKIHSTEGHKKAFSTCSSHLGVVSVLYGAVFFMYLTPDRFPELSKVASLCYSLVTPMLNPLIYSLRNKDVQEALKKFLEKKNIIL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 9K2, Olfactory receptor OR12-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPL_PHOV8
Sequence: MLLAVLLQSAAAAGLGKLGAALGAAIAVIGAGIGIGKIGGSAMEAIARQPEAAGDIRMNMIIIAALVEGVALIAIIVCLLTLFL
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL2_UREP2
Sequence: MAVKRIKNHSSGKRQTVVVDYKSILTTSKPEKSLLVTLPKKAGRNNQGKITIRHHGGGHKRKYRIIDFKRNKDNIYGTIKSIEYDPNRTSFISLVVYADGEKRYIIAPKGIKVGDKIISGNENIDILLGNSLPLEFIPEGTLVHNIELSPNAGGQITRSAGASAQILGFDETKKYILVKLNSGEVRKFRKECRATIGTVSNDEHILENLGKAGKSRHLGVRPTVRGSAMNPNDHPHGGGEGRSPVGMDAPRTPWGKRHMGVKTRNNKKSSTSMIVRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PKND_CHLPN
Sequence: MERYDIVRIIGKGGMGEVYLAYDPVCSRKVALKKIREDLAENPLLKRRFLREARIAADLIHPGVVPVYTIYSEKDPVYYTMPYIEGYTLKTLLKSVWQKESLSKELAEKTSVGAFLSIFHKICCTIEYVHSRGILHRDLKPDNILLGLFSEAVILDWGAAVACGEEEDLLDIDVSKEEVLSSRMTIPGRIVGTPDYMAPERLLGHPASKSTDIYALGVVLYQMLTLSFPYRRKKGKKIVLDGQRIPSPQEVAPYREIPPFLSAVVMRMLAVDPQERYSSVTELKEDIESHLKGSPKWTLTTALPPKKSSSWKLNEPILLSKYFPMLEVSPASWYSLAISNIESFSEMRLEYTLSKKGLNEGFGILLPTSENALGGDFYQGYGFWLHIKERTLSVSLVKNSLEIQRCSQDLESDKETFLIALEQHNHSLSLFVDGTTWLIHMNYLPSRSGRVAIIVRDMEDILEDIGIFESSGSLRVSCLAVPDAFLAEKLYDRALVLYRRIAESFPGRKEGYEARFRAGITVLEKASTDNNEQEFALAIEEFSKLHDGVAAPLEYLGKALVYQRLQEYNEEIKSLLLALKRYSQHPEIFRLKDHVVYRLHESFYKRDRLALVFMILVLEIAPQAITPGQEEKILVWLKDKSRATLFCLLDPTVLELRSSKMELFLSYWSGFIPHLNSLFHRAWDQSDVRALIEIFYVACDLHKWQFLSSCIDIFKESLEDQKATEEIVEFSFEDLGAFLFAIQSIFNKEDAEKIFVSNDQLSPILLVYIFDLFANRALLESQGEAIFQALDLIRSKVPENFYHDYLRNHEIRAHLWCRNEKALSTIFENYTEKQLKDEQHELFVLYGCYLALIQGAEAAKQHFDVCREDRIFPASLLARNYNRLGLPKDALSYQERRLLLRQKFLYFHCLGNHDERDLCQTMYHLLTEEFQL
What is the function of this protein?
Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.
What are the official names of this protein?
Serine/threonine-protein kinase PknD.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.