PharMolix/UniProtQA huggingface dataset:
Protein: F262_MOUSE
Sequence: MSENSTFSTEDSCNSSYKPHASNLRRAGKTCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYQSYDFFRHDNEEAMKIRKQCALVALEDVKAYFTEESGQIAVFDATNTTRERRDMILNFAKQNAFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYQPLDPDNYDKDLSFIKVMNVGQRFLVNRVQDYIQSKIVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAHALKKFLEEQEIQDLKVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYSEIEQRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNILVISHQAVMRCLLAYFLDKGADELPYLRCPLHIIFKLTPVAYGCKVETITLNVDAVDTHRDKPTHNFPKSQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSPLRALDMQEGADQPKTQVSIPVV
What is the function of this protein?
Synthesis and degradation of fructose 2,6-bisphosphate.
What are the official names of this protein?
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2, 6PF-2-K/Fru-2,6-P2ase 2, PFK/FBPase 2, 6PF-2-K/Fru-2,6-P2ase heart-type isozyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
Protein: ATG13_EMENI
Sequence: MHQQPRSPAPAASTSSARRSQDYDRRSDSPAFDLRTHTNRGLGIETENDTAEPEQSSQPGPEAISKVNQIVTNYHTKAALIILHSRVELPPSYAKNSNVPRVNRWFNVELEETDALKDQLKTWRTCDATDNRPPPMIIETYLDTAGLTNNQTLVALDDNGKRWDVTESLAASQSSRPAKASSSRAVDVILERWRVELGDMPGKLPSDLGAILPTVYKKSIILFRSLFTYSKFLPAWKFIKRNGRSRAHPALRVKYRIFSGHARDLSKQDHLTMPLFEGDTKVVDTYSFGVTDSPAGPFSVQVTYRTCCDFRVDDSEALLSSQFMGADDEIFQPSLPSGGLDARVTPEVGSAPLTRRTVEDPDLSRAYGSLSTFHHVGPTTGASPISALRAAREARASSPSPPTSSHRNSFAAARASPVGRAATLANDTNPNVARRPSISFQPFKAPPLSASPSLVDPPLSASPRTTGAGRTSLSDSRHMPPPSVTTSSRKPPSFGPDNANSSPNSASPRPTPMSRYSSAFSHRRGRPSSGGINKLEDDNSSGRASATSSGAQPGSGLLAEITGTSSDSIHADDENISEFLKMLDLRKDLLSPSSQTAMDNHSRRMTAASAALSRFRGMKDSNAALSDSMSSSLLMNRSSATSSKQLSGVPGIAGTSISTASSPGGKAISPHTPHTPAIPSRLSSNSIVDNTTTRLHGDNGSPVEEDASDETTTERLPSTVTAIPIPTSPATIFPSTFRRSSSAANRRSSHAIDDDEIFTMRSVSLGAEEPSHTTLGALQRQQDYEPIGTNIAPLESGARSSGGDDGNVLRGPTRRGPGAHRDASLSGPTVATSPYSHHPLHQRRISHSRGRGFSGGPHSLSSGSSSIARGGLIHPYPAEREAERDANAGASHSGTEDRRGTGRGSGGGRHNLPQAAQVEEDEPLLFAMSDFGASRRSFEEGRQGNHGPDSSGNTGSSRRGSGKRGTLSGFHLWP
What is the function of this protein?
Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy.  Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation.  Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy.  Finally, atg13 is also required for glycogen storage during stationary phase (By similarity).
What are the official names of this protein?
Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Fungi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: ANGI_CHICK
Sequence: MAMSSLWWTAILLLALTVSMCYGVPTYQDFLRTHVDFPKTSFPNIAAYCNVMMVRRGINVHGRCKSLNTFVHTDPRNLNTLCINQPNRALRTTQQQLPVTDCKLIRSHPTCSYTGNQFNHRVRVGCWGGLPVHLDGTFP
What is the function of this protein?
Ribonuclease that cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs).  Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus.  Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA.  Angiogenin induces vascularization of normal and malignant tissues.  Angiogenic activity is regulated by interaction with RNH1 in vivo.
What are the official names of this protein?
Angiogenin, Ribonuclease A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity).
Protein: SCRR_PEDPE
Sequence: MKPKLNDVAKLAGVSATTVSRVINNHGYLSSQTKEKVFAAMRELHYQPNNMARSLQGKNTRLIGVIFSDISNPFFGELVSRIEKILFAKNYKVILCNSADDPQKERDYLQMLMANQVDGIIAGAHNLGIEEYQQYGLPIISFDRYLSDNIPIVSSDNYQGGWLATQTLHQAGATNVAIFTGKSHAGSPTNGRREGYEAYLTAQQLTPHVHELPFELTPALKMMEIKTIMTQHQYDGIFCSDDLAALLVLNVAQQLSLTVPEQLRVVGYDGTALIRDYHSELTTVEQPLADISTLLVSLLLQRIEDANCTLESKYTLPVKLIKGFTA
What is the function of this protein?
Negative regulator of scrB expression.
What are the official names of this protein?
Sucrose operon repressor, Scr operon regulatory protein.
Protein: NAP2_SOLLC
Sequence: MVGKNNSNHLPPGFRFHPTDEELIMYYLRNQATSKPCPSSIIPEVDVYKFDPWELPEKTEFGEKEWYFFTPRDRKYPNGVRPNRAAVSGYWKATGTDKGIYSGTKYVGIKKALVFYKGKPPKGIKTDWIMHEYRLSESRTQPTRPNGSMRLDDWVLCRIYKKKNLERAIEMMKVEEDTQEPQIMSVTNPIHEVVASNGQQTLKLPRTCSLSHLLEMDYFGSISQLFDDNNSYNTISQNNTLMTNVNGYVMPHQAMEKFQLGEVSQISMNPSYQFQ
What is the function of this protein?
Transcription factor that binds DNA motifs 5'-CGT[AG](5N)NACG[ACT][AC][AT][ACG][ACT]-3' and 5'-CACG[ACT][AC][AT][AGT][CT]-3' in target genes promoters.  Promotes leaf senescence (developmental, light-induced and ABA-induced senescence) and regulates fruit yield and sugar content, probably by establishing abscisic acid (ABA) homeostasis.  Activates the expression of senescence and ABA associated genes including NCED1, ABCG40, CYP707A2, SAG113, SGR1 and PAO, by directly binding to their promoters.
What are the official names of this protein?
NAC domain-containing protein 2, SlNAP2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNTH_STAA9
Sequence: MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TREF_ECOK1
Sequence: MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARNWLKTVNQFYLEQHKLIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YWV1_CAEEL
Sequence: MPKIVIWNKVNDLDIFVDCKLNFQKHIEYVSNSAFLKCRQLLRCFRFTNVSLYFKLYNVYVQPLLNYGCEVYNPNSKRLIKLLEMPLKFYSRRVYQRCNVSNTSYDDRLAQSNQKSIQHQRILQILRTYHNILSGEYHFPDVSALKNSSAIPDSFFPKFGPFQLLTQLLPTSNPEYAQVLPNFSNSSVNSLARVLPKP
What are the official names of this protein?
Uncharacterized protein B0403.1.
Protein: PHT12_ORYSJ
Sequence: MAGSQLNVLVKLDQAKTQWYHFMAIVIAGMGFFTDAYDLFCIALVTKLLGRLYYTDITKPNPGTLPPNVSSAVTGVALCGTLAGQLFFGWLGDKLGRKSVYGFTLILMVVCSIASGLSFGHTPKSVIATLCFFRFWLGFGIGGDYPLSATIMSEYASKKTRGAFIAAVFAMQGFGILFGAIVALVVSAGFRHAYPAPSYAQNPAASLAPQADYTWRLILMFGTIPAGLTYYWRMKMPETARYTALVARNAKQAAADMSKVLHAEIEERPEVVESQVVAGETWGLFSRQFMKRHGMHLLATTSTWFLLDIAFYSQNLFQKDIFSKVGWIPPAKTMNALEELYRISRAQALIALCGTIPGYWFTVAFIDIVGRFWIQIMGFFMMTVFMLALGVPYDHWTHPAHHTGFVVLYALTFFFANFGPNSTTFIVPAEIFPARLRSTCHGISAASGKAGAIIGAFGFLYAAQDQHNPDAGYSRGIGIRNALFVLAGTNFLGMLMTLLVPESKGLSLEEMSKDNVVDETAQEAIAQA
What is the function of this protein?
Low-affinity transporter for inorganic phosphate (Pi) (PubMed:18980647).  Involved in internal Pi transport from root to shoot (PubMed:18980647, PubMed:20149131).  Responsible for most of the PHR2-mediated accumulation of excess shoot Pi under abundant Pi conditions, but not for PHO2-mediated accumulation of excess shoot Pi (PubMed:20149131).  Acts as a H(+):phosphate symporter (PubMed:18980647).
What are the official names of this protein?
Inorganic phosphate transporter 1-2, OsPT2, OsPht1;2, H(+)/Pi cotransporter, OsPT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYI_AZOVD
Sequence: MTDYKATLNLPETAFPMKAGLPQREPETLRHWNSIGLYRKLRQIGEGRQKFILHDGPPYANGNIHIGHAVNKILKDMIVRSKTLAGFDAPYVPGWDCHGLPIEHKVETTFGKNQPADLTRERCRAYAAEQVEGQKADFIRLGVLGDWENPYKTMDFANEAGEIRALAKMVEGGFVFKGLKPVNWCFDCGSALAEAEVEYQDKKSDAIDVFFPVGDADKLAAAFGLAQLDKPAGIVIWTTTPWTIPANQALNVHPDFIYALVDCGDRLLLLAEELVEGCLARYGLRGQVLATAKGEALELIRFRHPFYERFSPVYLADYVGLDAGTGIVHSAPAYGEDDFRSCKRYGMSNDEILSPVQSNGVYVESLPFFGGQFIWKANPNIVAKLAEVGCLLKHETISHSYMHCWRHKTPLIYRATAQWFVGMDSKAKDGTTLRERALAAIEQTRFVPAWGQARLHGMIAGRPDWCISRQRNWGVPIPFFLHKESGELHPRTVELMEEVARRVEQKGIEAWFRLDPAELLGAEADQYDKIADTLDVWFDSGTTHWHVMRGSHPMGHDQGPRADLYLEGSDQHRGWFHSSLLTGAAIDGHAPYRGLLTHGFTVDENGRKMSKSLGNVIAPQEITDSMGADILRLWVSATDYSGEMAVSKQILQRSADAYRRIRNTARFLLANLSGFDPAKDLLAAEDMLALDRWAVDRALLLQREVEEAFDSYRFWVVYQKVHNFCVQELGGFYLDIIKDRQYTCAADSVARRSCQSAMYHIGEALVRWIAPILAFTAEEIWQYLPGERNESVMLNTWYQGFAELPDGFALDRAFWEQVMAVKAAVNKELENRRNAKAIGGNLQAEVVLFAEPALAGRLALLGDELRFVLITSAAQVQPLGAAPADAVDTEVAGLRIQVSKSVHTKCARCWHHREDVGLDPAHPEICGRCVENIQGEGEVRQYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFP2_HUMAN
Sequence: MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ
What is the function of this protein?
Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network (PubMed:26507660).  May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660).  Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site (PubMed:31204568, PubMed:30917996).  Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria (PubMed:33773106).  In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658).
What are the official names of this protein?
Arfaptin-2, ADP-ribosylation factor-interacting protein 2, Partner of RAC1, POR1.
What are the subcellular locations of this protein?
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
Protein: RME6_DROPS
Sequence: MEPTAAGNLLEIMDLARTLRQEQLFIQQEQTAFGQLTGALETNAGTITKLAFVCAQQRQILNELLVARNDHDPLLSCRRASAYDSAQFMDAKQVLPYEHALAYEDLFNYLYNTPYLLALSLATADRLSLLSSGQLGQIINTIATGLYGNAINTKDVELLLKLLRELIEIQLLGSEQPRRLLRTNSSSFARLYQRLVESLFSARIFLTAALHAPLMGVLSEHDVWLDLDPHKLMQSFSQKERERRFGQAGEGEHGEEYQRNVARFHAETLGKLHTHAQVFVKSLQQSWALFPSSLRWLLQTLSQQLRQTHRHKEQEIRQLLTDLVFTHFISPAIVSADLVGIIDVNVSERMRHNLNQIVQLLQRLALNDEGSELVQLMELLMVGETGEDVVAILPQQTDFERSQLAINQRELSQFVEFFRLLTSRDEYDVSAEERQRLQRILGRIPKQQQQQQSQSELPDATANSPEKQQNNNNKKNNNRSLMRLGKAKKKLANSMSFSNSNSNSNKNLQPAVEQLPPLANGQANSSNISSASNGDLEQCSSHSGSNTSLSSCGAAPAAPTPAPTAVTNDHQYCARDEPVLMFSIYNASAKSKLKPLTEEEVLKMNCIGQDGSNLLPAVACTTGVVAPSSNNDDVSSLEAMRRPQDDASIGNSDNLEAISEAAHSVASSLDLEEQQERDVHENEDNLSDMVSANVSGRGTPNISGRDTPSSQVTDGDGGGGDMAHHHGHHVRAANPQMQKMLLSKARSDIDDKFCKFELKKFEVDENVSIISDTWSTDVLASDSENTLDATGSERGGDRGDRGDRDRDRNFSTPLIPSAVVLPGDNNFVVEALARAGAGVISGPHMDASDQRSESNWSTDVLASDSEKLAEIDTDDNASITAKSDIGPGSGGGAGVPEAGGGGGVVGDDDDEDEQTPGSSGDGEPDPDPDPDRERLRNGSERSQEDSAFFDAVNSYEDAHHLYHGASSLARSSVRTSYHVMGGESSFQQQYKSSGAEGIGRKTTPLMGTSCMRRQTSAESSISNQSLNLEEPPPPPRALAKHHHHHQHRDRDRDRDRDRDHREHHHKSAALKKKKHQEHKEHQHRDLIDFSDCSEDKDEEEQPPGLVQQLLDMFNQEEQQQQQQQQGCSSQSSVEHRRISMEQRSQCIDGRRNGILAGSMRRHQSLNYENHEIMLNSMLPKTDDDKQELLLCAQTQQQLQLEERAAAAENSCSNRAGAGAGAGARGTSKPPSKATGAIPKSISFDASADKEQQPYRDRERERDRERDRERDRDRERDRDRDRDRDRDREHHSAGIFNKLKQGFFKHRRGGSSSSKNNAIAIAAPSSINPNPSPSSATDPGGRSVSFDPSAGVCVSFGTHYCDSSEDILAKYRRKVSSSSEATNSDSTGNGAGGGAAAAAAAAAAHLHKHVNGGLLPGVAFGSVKQKLRTVLSKTDLHSGDFRQTTPMRPLDATTPLQIYLQIQLAQCISLQRLPQISHVAEALRCLEQLERPQHGQLLVELQHDLQRRQSYLQYLMRHRQQLLLRSEQLEQLEVRLRSEARSCQRCLMQSLVRLYLAWARQQDKLEQFQTEFGQLRASDERVELVEEFVEQLLQQLITSADLLDDWQVDAAREAIERMLLELMYQQVMFPNEDADVSRDTVLSAHIGKLQRFVHPAHPALCIAQEYLGEAPWTFAQQQLCHMAAYKTPREKLQCIINCISSIMSLLRMSCGRVPAADDLLPVLIYVVIMANPPYLLSTVEYISCFLGRKLDGENEFYWTLFGSVVKFIKTMDYLD
What is the function of this protein?
Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in endocytosis.
What are the official names of this protein?
Receptor-mediated endocytosis protein 6 homolog.
What is the protein family that this protein belongs to?
Belongs to the GAPVD1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: CPXY_BACSU
Sequence: MSSKEKKSVTILTESQLSSRAFKDEAYEFYKELRKSQALYPLSLGALGKGWLISRYDDAIHLLKNEKLKKNYENVFTAKEKRPALLKNEETLTKHMLNSDPPDHNRLRTLVQKAFTHRMILQLEDKIQHIADSLLDKVQPNKFMNLVDDYAFPLPIIVISEMLGIPLEDRQKFRVWSQAIIDFSDAPERLQENDHLLGEFVEYLESLVRKKRREPAGDLISALIQAESEGTQLSTEELYSMIMLLIVAGHETTVNLITNMTYALMCHHDQLEKLRQQPDLMNSAIEEALRFHSPVELTTIRWTAEPFILHGQEIKRKDVIIISLASANRDEKIFPNADIFDIERKNNRHIAFGHGNHFCLGAQLARLEAKIAISTLLRRCPNIQLKGEKKQMKWKGNFLMRALEELPISF
What are the official names of this protein?
Cytochrome P450.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: PRDX2_MACFA
Sequence: MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.  Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
What are the official names of this protein?
Peroxiredoxin-2, Thioredoxin-dependent peroxiredoxin 2.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLKA_DICDI
Sequence: MTIPTDNNSSNNKGYNDNNNNNNNNNNNNNNNNNNNNNNNKEHPNINNNNNNNNNNNNNNIKESSSSNSNHSSSQSSSTATVNSNPKVYPYEIIKQVGQGTFGKVYEAKNQDNKRVAIKKVEKSNHFISREYDILKIVAHPNCLRILDMFYTAEDNKKMQNLVFDFIPYTLASLLKKRQLSINFIKVLFYQLCQAIKHIHSKAICHRDITPNNILLSSKGELTLADFGSAKILESNHTSMSYICSRYYRAPELLVGCSNYTTKIDIWSIGCILAEMLIGKPLFPGTNSNDQLGRIIEVLGSPTKDDMEAMKPSKPYHLQLPNINPKFFESLHNVEDKTVVDLLSKIFIFDPVKRASIDEIIAHPFLRDVNINSLELFDEMKCFSVSGNGKSSLTTNSTSSSSTTANMTSLASSSSNNKTTCSETYLSRLPTSAITSSSNLKSIDNSNNGKSSSSSNNIPSLNNSNNGVITNTI
What are the official names of this protein?
Probable serine/threonine-protein kinase glkA, Glycogen synthase kinase-like kinase A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Protein: CM32_CONLE
Sequence: MLKMGVVLFTFLVLFPLATLQLDADQPVERYAENKQDLNPNERMKMIMSALGQRRCCISPACHEECYCCQ
What are the official names of this protein?
Conotoxin Lp3.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS7_CLONN
Sequence: MTTRKCNKFRKTSESEISLSLNLDGEGKSNIDTGIGFLNHMLNLMTKHGFLDLDIKAIGDLEVDAHHTVEDIGIVLGKALKEALGNKEKIKRYGTCFLPMDESLAFVSIDISGRAFLVYNCEFTVDKVGDMDTELVEEFLRAFAFNSEITLHTKILYGKNNHHMIEAIFKALGRAIKEAVLIDEKIKGVMSTKGII
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIG1_YEAST
Sequence: MQTVLKYLLLIMCGSFCASEELQNQTNVPAIFFSYKLTPGILKYQEDYDRAVTLPRDTFIEAAEKFLGVCNADTYVFINQPGLRKLDFLEFETEFVSLQRYIRRSSTAIKFEKVDLLPQDLYYDLAEFVKEYCNVDQVLNLRGNNTEDFQPFIDSEKRVIIIEYPKLPEDTNERKEAFRHYDKYLRTILAQIPSPEQNVIYTSLNPGTTLAHESIIPIQIFPDIFDIKSRVGEVEQNNRVLDVPRLSFNDYTPRFSEPPSEYVSIFDSQLIENNRGLLQLIFTILVGYILIQFFFTKKTIVDEKITNKKDNVKQTSPQLLKKVQEIQKKPSQQVS
What is the function of this protein?
Required for normal beta-1,6-glucan synthesis.
What are the official names of this protein?
Protein BIG1, Bad in glucose protein 1.
What is the protein family that this protein belongs to?
Belongs to the BIG1 family.
Protein: DC1L1_CHICK
Sequence: MAAVGRAGSFGSSSASGAANNASAELRAGGEEDDGQNLWSCILSEVSTRSRSKLPSGKSVLLLGEDGAGKTSLIGKIQGIEEYKKGRGMEYLYLNVHDEDRDDQTRCNVRILDGDLYHKGLLKFAMEANSLKDTLIMLVVDMSRPWTAMDSLQKWASVVREHIDKLKIPPEEMKEMEQKLVRDFQEYVEPGEDFPASPQRRNTSLQEDKDDSVILPLGADTLTCNLGIPVVVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRRFCLQYGAALIYTSVKENKNIDLVYKYIVQKLYGFPFNVPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKAEDSFEDSIRKPPVRKFVHEKEIVAEDDQVFLMKQQSQLAKQPPTAAGRPVDASPRVPGGSPRTPNRSVTSNVASVTPIPAGSKKIDPNMKAGATSEGVLANFFNSLLSKKTGSPGGPGGVGGSPGGGSAGGTGSNLPPSAKKSGQKPVLTDVQAELDRISRKPEMVSPTSPTSPTEGEAS
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  May play a role in binding dynein to membranous organelles or chromosomes (By similarity).
What are the official names of this protein?
Cytoplasmic dynein 1 light intermediate chain 1, Dynein light chain A, DLC-A, Dynein light intermediate chain 1, cytosolic, LIC57/59.
What is the protein family that this protein belongs to?
Belongs to the dynein light intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TM2D2_BOVIN
Sequence: MVLGGYPVSYLLLCGQAALLLGNLLLLHCVSRSHSHNATAEPELTSAGAAHPEGSPGAASWEYGDPHSPVILCSYLPDEFIECEDPVDHVGNTTAFQELGYGCLKFGGQAYRDVEHTRVQCRALDGIECASPRTFLRENKPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPSDGSNWCTIY
What are the official names of this protein?
TM2 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DBP7_ASPNC
Sequence: MADDGLLLNFAIPDTTVLRPEKTKVKGGTWRDRLSAKKIAAHRTNNPRKEKSASNGEQNSNPRNPNRIQVSGPRPVKRQRIEDDDGNGGSQPRQQQQQHPGAPRQFVSSLFSKNPRPRNAVEEKNEAGAEVEDAKPTNAPLIDGLDTFTNLGLSAPLAAHLLTKLEVKAPTAIQKASITQLLKEESDAFIQAETGSGKTMAYLLPLVQRIMTISLNQKKREEGEQVQRDSGLFAIVLAPTRELCKQIAVVLEGLLRCAHWIVAGTVIGGEKKKSEKARLRKGLNILVATPGRLADHLENTQALDVSNVRWLVLDEGDRLMELGFEKELAGIIQKLDARQRPSRIPGIPAKRTTILCSATLKMTVQKLGEISLKDAVHIQADPADEDGEPRKKDEDDAFRVPAQLKQSYAIVASKLRLVTLTAFMKRTFMRKGSVMKAIIFVSCADSVDFHFEVFTRKNGDEEEKKEESEDSDEEDAEEKRKKLGASAHGTIAPATAFSNPSNPVALHRLHGSLPQHVRTATLGAFARNREPSVLICTDVASRGLDLPNVDLVVEYDPAFSAEDHLHRIGRTARLGRDGRALIFLMPGCEEGYVDILKKGYRDGGKALTRNSADDILKRGFGGNVESQNVDWEEKATEWQLDVERWALENKNYLEMARRAYQSHIRAYATHIANERSMFNIKELHLGHLAKSFALRDRPSKINVPGLRQAQADTKKDFKADRKPVAGKKRKAGGHDDDDDDVPRQTDTLTAAQKMRAKMKEHMAGASEFNLA
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp7.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NO20A_SOYBN
Sequence: MRVVLITLFLFIGAAVAEDAGIDAITPEEGKANNIIEAYESPRFQKFVTHCSSHVTQTCSGNDPLNNQEASRMNSPFGLSFCLFDSMEKCLADHKASLKDPQDNNNLASMSSLPGSIQNQPLLIETVKFRTVLKTCSHVSAQYCFTNPNVATSALADCLMPSLNQCVYPGSILLPWPPPPPPPPPPPPPPPPPLI
What are the official names of this protein?
Nodulin-20a, N-20A, Nod-20A.
What is the protein family that this protein belongs to?
Belongs to the nodulin 20 family.
What are the subcellular locations of this protein?
Symbiosome, peribacteroid membrane. Symbiosome, peribacteroid space.
Protein: METXA_HALMA
Sequence: MNVEHNTVSLGEFEFDCGETIPELEITYEAYGEFDGDNAVLVCHALTGSAHVAGRDRVDSADQARAWWDDIVGPGKAIDTTEYYVVCANVPGSCYGSTGPKSENPETGEPYGTDFPPVTVTDWTEAQRALLDELGIPHLHAVVGGSVGGMNVIEWAKRHPDHVDRIVPIAAAARLDTQCLSLDAIARRAITTDPNWKQGHYYGEDDEPPSDGLALARQLGHVMYLSKASMERRFGRRAAGRDAVRTFPTDAAGAFFPYRDVESYLDYNAEKFTERFDANSYLYLTRAMDNYDLAAGFESDADALAAFDGDALVMSFTADWHFTTQQAEALADSLRAADANVAHHVIDSDHGHDAFLVEPDNVGPPLADFLDAGVDGNAVTDSVVEDSQESNFAPVHNSLFSQ
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SALPB
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMTEAQKPDTASYRTFNDFFVRPLRDDVRPLNTDPNILVMPADGVISQLGRIEEDKILQAKGHNYSLEALLAGNYLMADKFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPEGEHEGSVALLKGQEMGRFKLGSTVINLFAPGKVNLIASLASLSVTKIGQPLATSTETFVAPEVEPAPLPAEEIKAEHDASPLVDNKKDDT
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HEMH_PSEAB
Sequence: MTENALLLLNLGSPDSTRVEDVRRYLDQFLMDPYVVDLPWPLRRLLVSLILIKRPAESAHAYSSIWWDEGSPLIVLSRRLQEAMKPHWPHGPVELAMRYGQPAIEKVLLDLARRGIRRVTLAPLYPQFADSTTTTAEQEVRRVIAAHRLELEVSTLPPFYDQPVYLDALVESVRPYLQQPHDHLLLSFHGLPERHIRKLVKDPAHDLLAENSRNVSPEALALCYRSQCLRTAEAFAERAGLEQGRWSVSFQSRLGRAKWIEPYTDAKLDELVQRGVKRLLVMCPAFVADCIETLEEIGMRGREQFISAGGEDLVLIPCLNDHPAWVGALGEMSGRLARPL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.