PharMolix/UniProtQA huggingface dataset:
Protein: TPO12_CANGA
Sequence: MSSTSSDRPYDPLAPENEGVASSDVESTDSGEIRSYGPEEVLKNGSQIKDKGPALSKNSTQTSAVESAVAANRRLSKILTNTVDEPDVLEVDYSKCPPMGGGRPFPPTLPEKTQFEVTFDGPNDPLHPFNWPLRKKVMLCIILCLNCISITMGSSIFATGIRQICEIYHVIPVVAILGITLYVLGFAASPVIYAPLSEIYGRRGVLVISSFGFALFNFAVATAKDLQTIMICRFFAGFIGAAPLAVVPAAFADMFDTNIRGKAICLFSLGVFVGPILAPVIGSYITQHTTWRWLEYVIACFASAIFVAILFFFEESHHPSILVGKAKELRKLTGNWGIHAAHEDVELSVKEIAEKTITRPIIMLFTEPLLLIVTIYNSFVYGILYLLLEAYPIVFEQGYGFHTNGELPYISLIIGMAICGAFIWWMDEDYLRRYRKKGGLVPEARLLPMVVAGIVFPIGILWFCWTGNYPHKIHWIVPTIAGAFTGFGLIGIFLPCLNYIIESYLLIAASAVAANTFMRSGFGAAFPLFAGYMFNGMGVNYAGLLLGLLAVAMIPVPLLFLKYGPGIRKRSKYAYSL
What is the function of this protein?
Multidrug resistance transporter involved in resistance to azole antifungal drugs such as the imidazoles miconazole, ketoconazole, and tioconazole; as well as the triazoles itraconazole and fluconazole (PubMed:26512119).  Also plays a role in the resistance to other antifungal drug families such as the polyene amphotericin B, the pyrimide analog flucytosine, the fungicide mancozeb, and the polyamine spermine (PubMed:26512119).  Decreases the intracellular accumulation of clotrimazole by mediating its extrusion from cells (PubMed:26512119).  Plays a role in biofilm formation (PubMed:27780306).
What are the official names of this protein?
Multidrug transporter TPO1_2, Clotrimazole exporter TPO1_2, Drug:H(+) antiporter TPO1_2, DHA TPO1_2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMJ_ECOUT
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALSDITPRPQVVCLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_SHIFL
Sequence: MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPLADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQWPEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_SYMTH
Sequence: MDRSWAERRIPELIETIRHHEYLYYVKNEPEISDAAFDELMQELKQLEEAFPDLRRPDSPTQRVGGATAPDFAKVPHQPPMYSLDNAFSEADLRDFDRRVREGLGGEPVSYVCELKIDGLSISLRYEDGLFVQGATRGDGETGEDVTENLRTIGSIPLRLDGTEAPVPPRLIVRGEVYMTKQVLEELNAALAAEGKPLLQNPRNAAAGGLRQKDPRKTRERRLDAFLYQVVDAEALGIADHWSALQRLQAWRFKVNPHRHLAHTIDEVLDWVAGWQARRHELPYEIDGLVIKVNDLAQQRRLGFTSKFPRWAIAYKFPAEERETTVVGISLEVGRTGVVTPSADLAPVRIAGTTVKRATLHNEDYIREKDIRVGDTVIVRKAGEIIPEVVRVVPEKRPPDAQPWTFPKTCPACGAELVRIEGEAATRCTNNLCPAQQYRAILHFASRDAMNIEGLGEALVQSLLDHGLIEDAADLYRLHEKRDALIRLERMGEKSVDNLLAAIDATRQNPLHRLIFALGIRHVGERAARLLADHFGSMEAIEQAGLDELTAIPGLGPKIAESVKNYFASPRSHQLLAKLRAAGVNMVGEKKAGPAEGPLAGMTVVVTGTLVRWSRKEIEELIQQLGGKAAGSVSRKTSFVVAGEAAGSKLQKAQELGIPVLTEDEFCERYLQG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LOLA_CAMJE
Sequence: MKKTFLIFFIFIGQLFALDLNFNTFSSNFTQIVKSKNSTLSYSGHFILSKDQAYWSYDTPSKKEIYINKNQVTIVEHDLEQVIFSHLDNIPNLNEIFKKASLIDKDKLVAKYDNINYTIKLNQEQIQSISYKDEFENDVIINLNNQIKNPKINSDVFKAKIPQNYDIVR
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: 082L_IIV3
Sequence: MKYGLFLSQLERLVARWALVESPIVIKLGTRCRITLRKRHVDWTSHRFVVFPVKIYGLCVRHMNVLVWDMGHQRVERFEPFRMGFPEVQPTIDGALTNLLNQLAAADGSQTLQYRTLVTAWGNKSDHVDTHCCRWCLEWLEKKFPPPVEVGKNQGEKKQINK
What are the official names of this protein?
Uncharacterized protein 082L.
Protein: DBX1_RAT
Sequence: MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPTYLPRSIPTASLSPPRQEAPTALADSGTSDLGSPGSGSRRGSSPQTALSPASEPTFLKFGVNAILSSAPRRETSPALLQSPPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKTFQKQKYISKPDRKKLASKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGDEEEDSPGASLAYHAPPDPRHLLEGPLPASPAHSSSPGKPSDFSDSDEDEEGEEDEEITVS
What is the function of this protein?
Could have a role in patterning the central nervous system during embryogenesis.  Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons.  Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity).
What are the official names of this protein?
Homeobox protein DBX1, Developing brain homeobox protein 1.
What is the protein family that this protein belongs to?
Belongs to the H2.0 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBIG_SHEPC
Sequence: MQHNTNVDPQEIAKFERMAETWWDLNGEFKPLHLLNPLRLNYIDQTAGGIFGKKVLDVGCGGGILSESMARIGAEVDGLDMGEEPLEVARLHALETGVNITYVKNTAEAHSQDHQGYYDVVTCMEMLEHVPNPQSVIKACCDMVKPGGFVFFSTINRNLRSYVETILGAEYLLKMLPVGTHDHNKFIKPSELIELVDNTDLICKDAVGITYNPLTGIFKYTPRVDVNYMIATQKVD
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: PP233_ARATH
Sequence: MGGKNKIEILFQLQSALSRRRISSLVDFRRVFPPETPNHKNNITLSRFHFLGTHFLHSLGAPDKFPNRFNDDKDKQSALDVHNIIKHHRGSSPEKIKRILDKCGIDLTEELVLEVVNRNRSDWKPAYILSQLVVKQSVHLSSSMLYNEILDVLGKMRRFEEFHQVFDEMSKRDGFVNEKTYEVLLNRYAAAHKVDEAVGVFERRKEFGIDDDLVAFHGLLMWLCRYKHVEFAETLFCSRRREFGCDIKAMNMILNGWCVLGNVHEAKRFWKDIIASKCRPDVVSYGTMINALTKKGKLGKAMELYRAMWDTRRNPDVKICNNVIDALCFKKRIPEALEVFREISEKGPDPNVVTYNSLLKHLCKIRRTEKVWELVEEMELKGGSCSPNDVTFSYLLKYSQRSKDVDIVLERMAKNKCEMTSDLYNLMFRLYVQWDKEEKVREIWSEMERSGLGPDQRTYTIRIHGLHTKGKIGEALSYFQEMMSKGMVPEPRTEMLLNQNKTKPRVEDKMLRSNLTSEESESD
What are the official names of this protein?
Putative pentatricopeptide repeat-containing protein At3g15200.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: AP3M2_RAT
Sequence: MIHSLFLINSAGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVVEEIDAIIDKSGSTVTAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLSYHVSAQNLVAIPVYVKHSISFRDSGSLGRFEITVGPKQTMGKTIEGVTVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMGLQVGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT
What is the function of this protein?
Component of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  Ap47 is a subunit of the plasma membrane adaptor.  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity).
What are the official names of this protein?
AP-3 complex subunit mu-2, Adaptor-related protein complex 3 subunit mu-2, Clathrin assembly protein assembly protein complex 3 mu-2 medium chain, Clathrin coat assembly protein AP47 homolog 2, Clathrin coat-associated protein AP47 homolog 2, Golgi adaptor AP-1 47 kDa protein homolog 2, HA1 47 kDa subunit homolog 2, Mu3B-adaptin, P47B.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: SAU68_ARATH
Sequence: MMNTKKLMKMAKKWQQRAALRRKRISFQRSNSTTSSSSAVEKGCFVVYTADQVRFAFPISYLSNSVIQELLKISEEEFGIPTEGPITLPFDSIRFSWSISSN
What is the function of this protein?
May promote auxin-stimulated organ elongation, such as hypocotyls, stamen filaments and petals.
What are the official names of this protein?
Auxin-responsive protein SAUR68, Protein SMALL AUXIN UP RNA 68.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FTSB_ECOBW
Sequence: MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: ANR46_HUMAN
Sequence: MSYVFVNDSSQTNVPLLQACIDGDFNYSKRLLESGFDPNIRDSRGRTGLHLAAARGNVDICQLLHKFGADLLATDYQGNTALHLCGHVDTIQFLVSNGLKIDICNHQGATPLVLAKRRGVNKDVIRLLESLEEQEVKGFNRGTHSKLETMQTAESESAMESHSLLNPNLQQGEGVLSSFRTTWQEFVEDLGFWRVLLLIFVIALLSLGIAYYVSGVLPFVENQPELVH
What are the official names of this protein?
Ankyrin repeat domain-containing protein 46, Ankyrin repeat small protein, ANK-S.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TM2D3_XENLA
Sequence: MDLMMALKRVCRVLLFVTQMYVFSGRGSLSFEYSQPVAQPLKDTFPSSTTATSIKATTTKMPEYMEICPSNGQCSRLASDCMTCATNYSCIYGKLVTFNCTAKNGVVCFDENSQRQEYFTISMACQFCWQLPPSDYVCNLSSSCKTISCPRQRYNTTCTVLDHVHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVFLISVGYVGPADGSLYI
What are the official names of this protein?
TM2 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TWK7_CAEEL
Sequence: MTSSSRGYQRVDSSGDGGSLLMEEEGDNPHEALLHRNNDDYASTYHHVGVEYDSYEELERHEMDDRVTEIPEGFHRRQRRNLIYGDDVATDEELRVLRREALFGEEVTRAGLGRAEYYEDSHLIHSCDKSGHEDIDDESDDESKDEDEEEEETGIRKFAKLVLPHVALVLLTCTYTVIGALIFYSVEQPHEQMMKEQQLKLIYTRQNEFVDDLIRLAAGNETKRYEWESLAERHMHNMSDQLFVAFEKYFLTSNEVKKNAATETWTFSSSIFFAVTVVTTIGYGNPVPVTNIGRIWCILFSLLGIPLTLVTIADLGKFLSEHLVWLYGNYLKLKYLILSRHRKERREHVCEHCHSHGMGHDMNIEEKRIPAFLVLAILIVYTAFGGVLMSKLEPWSFFTSFYWSFITMTTVGFGDLMPRRDGYMYIILLYIILGLAITTMCIDLVGVQYIRKIHYFGRKIQDARSALAVVGGKVVLVSELYANLMQKRARNMSREAFIVENLYVSKHIIPFIPTDIRCIRYIDQTADAATISTSSSAIDMQSCRFCHSRYSLNRAFK
What are the official names of this protein?
TWiK family of potassium channels protein 7.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYL_LISW6
Sequence: MTFNHKKMEPKWQQYWSEHNTFKTTEDKDKENFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGKNVLHPIGWDAFGLPAEQYAIDTGNDPEEFTALNIANFTRQIKSLGFSYDWDREINTTDPEYYKWTQWIFEKLYENGLAYEAEIAVNWCPALGTVLANEEVIDGKSERGGFPVFRKPMRQWMLKITAYADRLLDDLDLVDWPENIKDMQRNWIGRSEGAEVTFKIKDSDETFNVFTTRPDTLFGATYTVFAPEHELIEKITTPEQKEAVETYKKQVELKSELERTDLAKDKTGVFTGAYAINPINGEEVPIWIADYVLIQYGTGAIMAVPAHDERDFEFAQQFGLNIRPVLEGGDVTKEAFTGDGPHINSEFLDGLAKEEAITAAIDWLEKEGIGSRKITYRLRDWLFSRQRYWGEPIPVIHWEDGETTLVPEEELPLLLPKATEIKPSGTGESPLANLHDWVNVTDESGRKGRRETNTMPQWAGSSWYFLRYIDPKNTEAIADKEKLIEWLPVDVYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLFNQGMILGENNEKMSKSRGNVVNPDEVVEKYGADTLRMYEMFMGPLDASIAWNENGLEGARKFLDRIWRLFVTEEGILAEKVTTTANANLEKAYHHMVKTVTNHYENLRFNTGISQLMIFINEAYKQDSIPKEYVEGFVQLLSPIAPHLAEELWEILGHTETISYVTWPTYDETKLVEDEVEIVLQVNGKVKSKITVAKSLGKEELEKIAQEDDKMKENLEGKTIRKVIVVPGKLVNIVGN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_ALBFT
Sequence: MSHQPYFADNHPMTSTLNADPAELAKFSDLAHRWWDLEGEFRPLHQINPLRLEWINHLCPVAGQQVLDVGCGGGILADSMARLGAQVTGIDLASKALRVAQLHALEAQTPNLQYQEISVEALAAQQPGSFDVVTCMEMLEHVPDPASVVRACATLVKPGGWVFFSTLNRSPKSFVLAIVGAEYVLNLLPRGTHEYAKMIRPSELASYCRSVELDLRHTRGMQYNPLTRRYWMSDDTSVNYLFATQKSNAAIL
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: SYK_STAAU
Sequence: MSEEMNDQMLVRRQKLQELYDLGIDPFGSKFDRSGLSSDLKEEWDQYSKEELVEKEADSHVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEFDLWKNADLGDIVGVEGVMFKTNTGELSVKAKKFTLLTKSLRPLPDKFHGLQDIEQRYRQRYLDLITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDLTESMVRHIANEVLGSAKVQYNGETIDLESAWTRLHIVDAVKEATGVDFYEVKSDEERKALAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPTFIYGHPTEISPLAKKNPEDPRFTDRFELFIVGREHANRFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDEDYIEALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB1F2_I68A3
Sequence: MEQEQDTPWIQSTGHINIQKRENGQQTLKLEHHNSIQLMDRCPKTMNRAVMLKQTVCWRQWLFLRSPTPVSLKTRVLRRWKPSSKHGWTN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: YRMC_CAEEL
Sequence: MDSEKENPASPTTGREEEIPGSSPEGVYPADEDHIFHEDQAPLRVESAKHEEEIVEQQQQQPEDLEQGDMIVEDGDQQFMNMVQITQEDMYEAGFDVEAGFELNHLTEEQLNIVVAISQQRQAKQNEQEHNEEVVIEDGSHHHMVHHEMIENQFEGDGNGPEEEYDGNGQIIDNAMHIILTNDGGVNITSKQKQFYVSPSEIANLNIDLNNLSTENVHQLVQLALPPIKEKAQDSAYNDQAPSTSYHHHHHEQLEAGKSTRSPIIGETVQIRTADGRLQDAVVKYVRGDSEYKIQLMNGEFAYATIDQMLVPQRDRSDHEYQQVAPPVLLRRTDMASVRNAAQKRSANDDLCPPVLKKSYQLAPVVDGPHLVHTPNFCCPICDKKVYQKEPSYIVIRLPACDSCTREKIIVLDEQSS
What are the official names of this protein?
Uncharacterized protein R06F6.12.
Protein: DNAA_UREPA
Sequence: MANNYQTLYDSAIKRIPYDLISDQAYAILQNAKTHKVCDGVLYIIVANAFEKSIINGNFINIISKYLSEEFKKENIVNFEFIIDNEKLLINSNFLIKETNIKNRFNFSDELLRYNFNNLVISNFNQKAIKAIENLFSNNYDNSSMCNPLFLFGKVGVGKTHIVAAAGNRFANSNPNLKIYYYEGQDFFRKFCSASLKGTSYVEEFKKEIASADLLIFEDIQNIQSRDSTAELFFNIFNDIKLNGGKIILTSDRTPNELNGFHNRIISRLASGLQCKISQPDKNEAIKIINNWFEFKKKYQITDEAKEYIAEGFHTDIRQMIGNLKQICFWADNDTNKDLIITKDYVIECSVENEIPLNIVVKKQFKPEQIIEIVAKELNIKTDLIKSSIRKNNIVWARDIVCYILKNKLNLTLTDIGKLLNGREHTTISHSISKVQKILDDENSQEALQINLIINKF
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TO201_ARATH
Sequence: MDKLNFFEEIRKDAEETYKLNPEDADNLMRWGEALLELSQFQNVIDSLKMIQDAISKLEDAILIDPMKHDAVWCLGNAYTSYARLTPDDTQARLNFGLAYLFFGIAVAQQPDNQVYHKSLEMADKAPQLHTGFHKNRLLSLLGGVETLAIPSPKVVKNKKSSDEKYIVMGWVILAIGVVACISFRKLR
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM20-1, Translocase of outer membrane 20 kDa subunit 1.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: SYP_ALIF1
Sequence: MRTSKYLLSTLKETPNDAEVVSHQLMLRAGMIRRLASGLYTWLPTGLRVLRKVENIVRQEIDNAGAIETLMPVVQPFELWEETGRSEKMGPELLRFTDRHVRPFVLSPTAEEVITSLVRNEVSSYKQLPLNLYQIQTKFRDERRPRFGVMRAREFCMMDAYSFDINKEGLQKSYDAMHDAYCKAFDRMGLEYRPVLADSGAIGGSGSQEFHVLAESGEDLIAFSTESDYAANIEKAEAVAPTTERAAPTQEMTTVDTPNAKTIAELVEQHGIAIEKTVKTLFVKASDEVDADIIALIIRGDHELNEVKAENLPQVASPLEMADEAQLRDLIGAGAGSLGPVGLELPFIVDRSVAVMSDFGTGANIDGKHFFGVNWDRDVQLGQVEDLRNVVEGDPSPCGKGTLQLKRGIEVGHIFQLGTAYSEAMNCGVLDANGKNVILEMGCYGIGVSRVVASAIEQNNDEYGIVWPEAIAPFTVAIVPMNMHKSERVKEAAEKLYAELTAMGIEVLFDDRKERPGVMFKDIELIGIPHTIVIGDRSMDEGHFEYKNRRANTKEAVEMANIVEHIKAQLS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFE1_ARATH
Sequence: MAAAMSSSCCASSLRLIPFKRTLFSSIHYPAKTLLLRPLKPSEVPSFRRTIITFQKISTGIVPPPSASSSPSSYGDLQPIEELPPKLQEIVKLFQSVQEPKAKYEQLMFYGKNLTPLDSQFKTRENKVEGCVSQVWVRAFFDEERNVVYEADSDSVLTKGLAALLVKGLSGRPVPEILRITPDFAVLLGLQQSLSPSRNNGLLNMLKLMQKKALHLEVKGEEDSSSGESSESSFVSIPETKDEANVPEVDLESKPDLVEDLGTEKIDDSESGSNVVALGSRGMRIREKLEKELDPVELEVEDVSYQHAGHAAVRGSAGDDGETHFNLRIVSDAFQGKSLVKRHRLIYDLLQDELKSGLHALSIVAKTPAEV
What is the function of this protein?
Participates in cysteine desulfurization mediated by NFS2 in chloroplast and NIFS1 in mitochondrion (PubMed:16437155).  Activates the cysteine desulfurase activity of NFS2 (PubMed:16455656).  Cysteine desulfurization mobilizes sulfur from L-cysteine to yield L-alanine and supplies the inorganic sulfur for iron-sulfur (Fe-S) cluster formation.  Glutaredoxins regulate SUFE1 activity by inducing its reduction and deglutathionylation (PubMed:24203231).
What are the official names of this protein?
SufE-like protein 1, chloroplastic/mitochondrial, Chloroplastic SufE, CpSufE, Protein EMBRYO DEFECTIVE 1374, Protein SULFUR E, AtSUFE, Protein SULFUR E 1, AtSUFE1.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Mitochondrion.
Protein: ACTT2_HUMAN
Sequence: MFNPHALDSPAVIFDNGSGFCKAGLSGEFGPRHMVSSIVGHLKFQAPSAEANQKKYFVGEEALYKQEALQLHSPFERGLITGWDDVERLWKHLFEWELGVKPSDQPLLATEPSLNPRENREKMAEVMFENFGVPAFYLSDQAVLALYASACVTGLVVDSGDAVTCTVPIFEGYSLPHAVTKLHVAGRDITELLMQLLLASGHTFPCQLDKGLVDDIKKKLCYVALEPEKELSRRPEEVLREYKLPDGNIISLGDPLHQAPEALFVPQQLGSQSPGLSNMVSSSITKCDTDIQKILFGEIVLSGGTTLFHGLDDRLLKELEQLASKDTPIKITAPPDRWFSTWIGASIVTSLSSFKQMWVTAADFKEFGTSVVQRRCF
What are the official names of this protein?
Actin-related protein T2, ARP-T2, Actin-related protein M2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y1480_AQUAE
Sequence: MSLLTRRLKPYYEELLEPLVNFFGKYNVSPNLITLFGLFLVGLGSFFLYLENLILAFLLLLLGALADSIDGALARRLNLKTEFGAFLDSTVDRFSDALPFTALGVHYASYGDETGVLLSFLALISSFGVSYTRARAESLGVYGLGGVFERTERWIVLLGSILLGLLKLGLFIITLGSLITVFQRVYETKKALEVKR
What are the official names of this protein?
Uncharacterized protein aq_1480.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.