PharMolix/UniProtQA huggingface dataset:
Protein: CNBL9_ORYSJ
Sequence: MESGYGFRFSDDDVESASSLTVGERLCAAFLPFVAIAEAVFFALTDCLADLLPPSAAASRHRRSAASSYLAAVARKWNHQQRGRVGIGCTSLTLRQLARLADESRCFSVNEVEALFELYKKISCSIIDDGLIHKEELQLALFKTPSGQNLFLDRVFDLFDEKKNGVIEFDEFIHALSVFHPLAPLEDKINFAFRLYDLRQTGFIEREEVMQMVIAILSESDMKLSEELLEAIIDKTFEDADADRDGKINQQEWKEFVLRHPNLLKNMTLPYLRDITTVFPSFVFNTAVED
What is the function of this protein?
Acts as a calcium sensor.  CBL proteins interact with CIPK serine-threonine protein kinases.  Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
Calcineurin B-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
Protein: RUTB_ECO55
Sequence: MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: NUOK_STRM5
Sequence: MITLGHMLALGAVLFAISLAGIFLNRKNVIVLLMSIELMLLSVNVNFVAFSRQLGDPSGQLFVFFILTVAAAEAAIGLAILVTLFRTRRTINVGEVDSLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS6_STRCO
Sequence: MTLAVRVIPCLDVDNGRVVKGVNFQNLRDAGDPVEMAKVYDAEGADELTFLDITASSGNRETTYDVVRRTAEQVFIPLTVGGGVRTAEDVDKLLRAGADKVGVNTAAIARPDLIREIAERFGRQVLVLSVDARRTEAGTFEVTTHGGRRGTGIDAVEWAHRAAELGAGEILLNSMDADGTKDGYDLEMLAAVRKHVSVPVIASGGAGSLAHFAPAVEAGADAVLAASVFHFGDLRIGEVKTTLREAGHPVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEKT4_BOVIN
Sequence: MAQTDILLTKEPAPQTVPACQLPRKLYDVARNTGAHTSSGLATSGFRTAKYLLDEWFQNCYARYHQAFADRDQSERQRHESQQLAAETEALAQRTQQDSTRKVGERLQDMHGWKSELQRQVEELVSETELLLAQKQRLERALDATAGPFSIVTDNLQCRERRQHPDLVRDCVEIELLKEAELIRNIQELLKRTIKQAVSQIRLNWEHKETCEMDWSDKVEAYNIDEACCRYNNQSTDVQFYPHSAKFEESASTPETWAKFTQEHLYRAERERLASVNLRNLIDCILQDTSEDLRLQCDAVNLAFGRRCEELEDARHKLEHHLRKTLREISDQEHNIAALKQAIKDKEAPLKVAQTRLYQRSHRPNVELCRDAAQFRLASEVEELNLSLAALKEKLLEAEQSLRNLEDTRMSLEKDIAIKTNSLFIDRHKCMAHRAHYPTVLQLAGYQ
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme.  Forms filamentous polymers in the walls of ciliary and flagellar microtubules (PubMed:34715025).  Contributes to normal sperm motility (By similarity).
What are the official names of this protein?
Tektin-4.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Note=Found in the abaxial (convex) surface of outer dense fibers in sperm flagella.
Protein: HUL4_ASHGO
Sequence: MSFFSRNINSKDRHKIQIISNSTAPSFEPNNEFVTSSCCCCGTILQHPKNISKFRCSVCYVTVVLQGTAFTQDKTELFDLDDMRELLSSCNNTYRELDKDEKRLRKHEVFHLLEDYIATRMVTIFPLNASFESSNPREMLDYDQVKEFYRILMELPTKKPFYSFLVACNELLKRPHVALNTPTPTNPKYKRIGLFRWILIILEVPIFKQTLANAEARCNTPHFRAISYEVLKKAVGYMSCLDEASAKELVHFLKYMQKDIFASKVELVNMYITFHFARILHTIGKETNNGKYSPQLEDFEHSEKLNPSLNQGSAKKLVHTNMNIFFGGIVRPMTSSANSKDILALNYRFSPEDYGNEWHIKTGARLLLCLYVANQSAYKCPVSNFYNTMIDFVDYKRDFELWQDLSKLSASHEKENSGSSGPRYSPVQFTICQCPFLFSLGMKISILEYETRRLMEYSAEQAFLKALDRKQVVDVYLKIRVRREFVTTDSLRSIQNQQKDLKKSLRIEFVNEPGIDAGGLRKEWFLLLTRDLFNPNNGLFVYVPESRLCWFSIMESIEHELLQGEGSSSELYYLFGVVLGLAIYNSTILDLKFPRAFYKKICGEVLSVNDFLELYPETGTNMLKMLEYDGEDFEDIFALTFETCFPDRFDESKIHYRQLCPDGSTQAVTRENKHEYFRLWMDFYLNRSIAPGFESFRNGFFHVIEGNSFRLFGSEELEQLVCGSNEQSLDVSMLRSVTRYQGGFDDNSPVVQWFWEILSEMEYPQQRKLLHFVTGSDRVPATGVTTIPFRISRIRSGADRLPLSHTCFNEICLHEYKDKETLRNKLIIALEESQGYGFR
What is the function of this protein?
Probable E3 ubiquitin-protein ligase, component of the TRAMP complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism limiting inappropriate expression of genetic information.  Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase HUL4, HECT ubiquitin ligase 4, HECT-type E3 ubiquitin transferase HUL4.
What is the protein family that this protein belongs to?
Belongs to the HUL4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARSS_METTH
Sequence: MMNDKKITSFIALPDLLSMLNASSGYLSILLSIDGSLNAACILMLLAVLFDSLDGWVARKTGRIDIHGFGKNMDSLSDVISFGVAPAILIYSAAVDFRYINILVGPLIVLCGILRLSRFNVLTGGGKNFTGLPIPVAAVTISSFYLTGFYSELSAAFIMIAVSVLMISSIEYPRVDGMGASTALILIIATIISVAAVEILQAASVVAGPVAIILFIATLTYIAVPILPKRDVI
What is the function of this protein?
Involved in the lipid biosynthesis.  Catalyzes the formation of unsaturated archaetidylserine from CDP-unsaturated archaeol and L-serine.  Activity with ester-linked substrate analogs containing straight aliphatic chains (typical bacterial substrates) is two to three times higher than that with the corresponding ether-type substrate (typical archaeal substrates).  Both enantiomers of CDP-unsaturated archaeols with ether-linked geranylgeranyl chains and CDP-saturated archaeol with ether-linked phytanyl chains are similarly active.  The enzyme also accepts D-serine, although activity is only about third of that with L-serine.
What are the official names of this protein?
Archaetidylserine synthase, CDP-2,3-di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: PHB1_CHICK
Sequence: MAAKVFESIGKFGLGLAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDTVVGEGTHFLIPWVQKPIIFDCRSRPRNIPVITGSKDLQNVNITLRILFRPVTAQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSEDLTERAATFGLILDDVSLTHLTFGKEFTEAVEMKQVAQQEAERARFIVEKAEQQKKAAVISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPSGQSVLLQLPQ
What is the function of this protein?
In the plasma membrane, cooperates with CD86 to mediate CD86-signaling in B lymphocytes that regulates the level of IgG1 produced through the activation of distal signaling intermediates.  Upon CD40 engagement, required to activate NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation.
What are the official names of this protein?
Prohibitin 1.
What is the protein family that this protein belongs to?
Belongs to the prohibitin family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Nucleus. Cytoplasm. Cell membrane.
Protein: YIJD_ECO57
Sequence: MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLVLTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIMVFWIGAKMRNRKQEVAE
What are the official names of this protein?
Inner membrane protein YijD.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATC_JANSC
Sequence: MSIDESTAAKVAKLARIKVEDDALPALANEFNAILGFIEQLEEVDVEGVDPMVSVTPMALPRREDVVTDGDQQTRVLTNAPDAREGFFSVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: ELAV4_DANRE
Sequence: MFEISRTLNAALLSNEGSTETQWRQADLPQLQGWAEKGLLTQPKMIISNMEPQVTNGPNSATANGPSSNSRSCPSPMQTGGSNDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGPTGGSRGVGFIRFDKRIEAEEAIKGLNGQKPSGAAEPITVKFANNPSQKTSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDSMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKTHKS
What is the function of this protein?
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs (By similarity).  Plays a role in the regulation of mRNA stability, alternative splicing and translation (By similarity).  Binds to AU-rich element (ARE) sequences in the 3' untranslated region (3'UTR) of target mRNAs (By similarity).  Mainly plays a role in neuron-specific RNA processing (By similarity).  Required for the maturation of motor neuron axonal branches and dendrites (PubMed:29061699).
What are the official names of this protein?
ELAV-like protein 4, Protein elrD.
What is the protein family that this protein belongs to?
Belongs to the RRM elav family.
What are the subcellular locations of this protein?
Cytoplasm. Perikaryon. Cell projection, axon. Cell projection, dendrite. Cell projection, growth cone.
Protein: COX3_GAZDO
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLIMWFHFNSTTLLMLGLTTNMLTMYQWWRDVVRESTFQGHHTPNVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FOLD_METTP
Sequence: MIIDGKALASDIEAEVRERVERLGFNPGLATILVGENPASQMYIRIKHAACERVGIRSENIVLPGDTDESTLIKTIQGLNKRGDVHAILLQLPLPGHLDPRKAMMAISPEKDADGFHPENMGALLLGAERLVPCTPRGIVYALEHLGVDIEGSEAVIVGHSNVVGKPLAAMLLNRNATVQVCHVYTRNLKEHTKDAEILVVAAGVPRLIKADMVRDGAYVFDVGINKVDGKTVGDVDFDAVKEKAAGITPVPGGVGPLTVAMLLSQTVTAAEMSLERQRS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HOT1_ASHGO
Sequence: MIDPVTHIVTPSNDEQRQGRSDGGMQLGLEDLHGGGGGLGQQKVSGMAEGTDSIVDVLTNPSSSVNLHSNILSVSTNVEEGQGMQPAAIQGGGTAAGRRFSSVPISDSPVGCGQHGMGTASTQVPSHGSTANLLSMGNPVATNVQVCQRMDEVSARLIVMEETVNKLLGNIDAQQQQIASMRSESMEMLGSLMKEVRELKQQVPVLDDPDNNEKDKFVTDLLNSITNVSSNYLKKVSSRNLQRFKRQRDIMSTSDLPSLGNTQSSSHFMQDLVNPYASTQDFQSFTVLKDKAKEFTLNPTAINKRRRLSAQPLNTLQMSQDQLQQQRGSVQSLISIPTSGQKNANFGPQLQNYLIGLQNIPMSEAEKVSSPTVLKQFQNSTTDPDLKTGRRNPGLDFQIGSGDDENDENDGASGEDEDGYLEDDEGYRSQSQRTMSSEDDEQFTGGNQGEDEAGPRAAGRNPKSLPSSIVRRFANSGSQVSVSGTPETERLVLKNNDKYDKNTMPAPNTKPRAVLASNPEDTLTDVQYTMVKAPDSVRAIWDEYTIGVGGKPSIRQLEQTYGNKWRTKRNKKTFARRKRIYKFILNGVRNGKSESEMIDILESRRVYRTEDNELKKRTIGWLQQSLSGI
What is the function of this protein?
Required for a complete transcriptional response to osmotic stress.
What are the official names of this protein?
High-osmolarity-induced transcription protein 1.
What is the protein family that this protein belongs to?
Belongs to the HOT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADD_PARL1
Sequence: MARRELLTPGLKVGLLGGSFNPAHEGHLHVTRMCLRALGLDRVWWLVSPQNPLKSDAGMASFDRRLASAEKMARDPRICVSDIEARLGTRYTVDTLAALTSRFPQIRFVWLMGADNLIQLPHWARWRDIVQTVPIAVYPRPGFTLKARLSPAATALRDVTLDATDAALLPLLTAPALAFLDGPESSQSATSIRERGGWSLR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ASTB_BURM1
Sequence: MNAQEANFDGLVGPTHNYAGLSFGNVASLNNEKSVANPKAAAKQGLRKMKQLADLGFAQGVLPPQERPSLRLLRELGFSGKDADVIAKAAKQAPELLAAASSASAMWTANAATVSPSADTADGRVHFTPANLCSKLHRAIEHEATRRTLSTLFADRARFAVHDALTGTPALGDEGAANHTRFCAEYGKPGVEFFVYGRSEYRRGPEPKRYPARQTFEASRAVAQRHGLAEEATVYAQQDPDVIDAGVFHNDVISVGNRDTLFTHERAFVNKQAIYDTLTAALDARGARLNVIEVPDAAVSVNDAVTSYLFNSQLLSRADGSQVLVVPQECRENANVAAYLDHLAAGNGPIRDVLVFDLRESMKNGGGPACLRLRVVLTDAERAAVTSNVWIDDTLFTVLDAWIEKHYRDRLAPDDLADPALLVESRTALDELTQILRVGSLYDFQR
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: PQQC_RHOPA
Sequence: MNAMTAFSLNGAAPLANADELEAALRQIGAARYHNLHPFHRLLHGGKLNKGQVQAWALNRYYYQSSIPIKDAVVISRFRDRATRVEWRHRIEDHDGDLSSEGGIERWLKLTEGLGLDSGYVESTQGILPATRFAVDAYVHFVRDRTPLEAIASSLTELFAPNLHEERIAGMLAHYDFVNPEIMSYFKRRLEQAPRDADFALRHVKQHATTPAEREAVCNALIFKTNVLWAQLDALHHAYVDGHIPPGAFVPQGF
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: TOM20_RAT
Sequence: MVGRNSAIAAGVCGALFIGYCIYFDRKRRSDPNFKNRLRERRKKQKLAKERAGLSKLPDLKDAEAVQKFFLEEIQLGEELLAQGDYEKGVDHLTNAIAVCGQPQQLLQVLQQTLPPPVFQMLLTKLPTISQRIVSAQSLAEDDVE
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity).  Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM20 homolog, Mitochondrial 20 kDa outer membrane protein, Outer mitochondrial membrane receptor Tom20.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: MPAL2_LOLPR
Sequence: AAPVEFTVEKGSDEKNLALSIKYNKEGDSMAEVELKEHGSNEWLALKKNGDGVWEIKSDKPLKGPFNFRFVSEKGMRNVFDDVVPADFKVGTTYKPE
What are the official names of this protein?
Pollen allergen Lol p 2-A, Allergen Lol p II-A.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS4_METAC
Sequence: MAFEVIPAVDMRGGKCVQLVQGVPGSEIVSLNDPLAVALDWIGKGAKTLHLVDLDGAIEGERKNAPIIEKIVQACREKGVSIQVGGGIRSFEDAASLLELGVSRIILGTAALQNPELVKQLSDAFGSSCVNVALDAKNGKISIKGWTEECAQTPVEMGREFEELGAGSLLFTNIDTEGLMQGVNPGPTRELVESVSIPVIASGGVSSLEDLKVLKQTGASGVVVGSALYTGRFTLEAAIETIRND
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_BIFLS
Sequence: MSLIDQAREQMAKTVENTKENFSGIRTGRANPALLNGITVDYYGAPTPIKAVASIGVPEPRTLSVTPFDASQAGAVEKALRNSDLGVSPNRDGNVIRLTMPELTEERRKEYVKLAKGKAEDGKVAVRNIRRKTKEALDKAVKDGEMGEDEGDRLLKDLDKVTKSVTDEIDALLESKQKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_IGNH4
Sequence: MAKWIVGSAWPYVNTVPHLGNLIGSVLSADVFARFLRLMGEDVVFVSGSDEHGTPIEVEARKRGVEPKELTDKVHEYVKKLFEKYLISFDNYTRTHNPVHMEFVRETFMKIYENGYIFTQEMVMPYCPKDKMFLPDRFTVGTCPYCGAPDARGDQCERCGKLLDPPDLVNPRCAFCGSRPVWRKTLHWFFDLPKAAEGLVEWLERSELPNNVKKFTLNWVKEGLTPRSVTRDNKWGIPAPFPGAEGKTIYVWFEAVLGYLSAVKELDVKNGTNLFEEFWKDINSRPVYFIGKDNIPFHSIILPALLKATGEEYPLPYNISATEYLMYEGQKFSKRRRVGVWIDEALEVVPNPDYWRFALIRMRPEERDTNFTWREFYRIVNSELNDDIGNFAHRVLTFVERRFGGSVRGRVDEEVKKSIAELHEKYVKAMYKVKLKEASGLVLEMARLGNKYLNEKEPWRLLKEGKEEEARDVMYTCLFILREVALHLAPFAPSAAEELWKMIGEPGSVHERGKLLTSGSEPAGEVKEPKPLFQKLPKDFLERVDELLEEARRKVEKLRPI
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAGC2_HUMAN
Sequence: MPPVPGVPFRNVDNDSPTSVELEDWVDAQHPTDEEEEEASSASSTLYLVFSPSSFSTSSSLILGGPEEEEVPSGVIPNLTESIPSSPPQGPPQGPSQSPLSSCCSSFSWSSFSEESSSQKGEDTGTCQGLPDSESSFTYTLDEKVAELVEFLLLKYEAEEPVTEAEMLMIVIKYKDYFPVILKRAREFMELLFGLALIEVGPDHFCVFANTVGLTDEGSDDEGMPENSLLIIILSVIFIKGNCASEEVIWEVLNAVGVYAGREHFVYGEPRELLTKVWVQGHYLEYREVPHSSPPYYEFLWGPRAHSESIKKKVLEFLAKLNNTVPSSFPSWYKDALKDVEERVQATIDTADDATVMASESLSVMSSNVSFSE
What is the function of this protein?
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases.  In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation.  Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
What are the official names of this protein?
Melanoma-associated antigen C2, Cancer/testis antigen 10, CT10, Hepatocellular carcinoma-associated antigen 587, MAGE-C2 antigen, MAGE-E1 antigen.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Nuclear in germ cells. Cytoplasmic in well-differentiated hepatocellular carcinoma, nuclear in moderately- and poorly-differentiated hepatocellular carcinoma.
Protein: GPMI_MYCMS
Sequence: MKVKRPVLLAILDGWGISEPDKGNAVDNANMVFVEYLKKTYPWLKAHASGKWVGLPENQMGNSEVGHIHLGAGRINLESLAKLNHETKTNNIAKNDEIVKTFEYVKKNNSALHLMGLFSNGGVHSHFDHMIAIYKAAIDYGITNIKFDLITDGRDTKPKLAYDFIKDLLELIKQNNNIGIISSISGRYYAMDRDKRFDRSRIAYNAIVNRNNVRSFTNILDYIQQEYMINHDDEMIIPAFNQDDLNGNLKANDAIIMTNFRPDRAIQISSILTNKNYIAWQNEAFSDAEFIGDKIRFVSMMKYSDSVTSPHIAYPPKPLTNTLGQYLSQLGLKQLRIAETEKIAHVTFFFDGGNDYFKNGLAKNDEITLANAYIDLIPSAKVATYDLKPQMSAVEITDKLLEEIKKDEFDFIVLNFANCDMVGHTGNNKATEIACKTLDEQLKRIHEEFVLRHNGIMVITADHGNAEIMIDKDGQVNKKHTTSLVPIIITDLNIKLKQNDPEIAKVAPTILDLMNIEIPKEMELESMIDHN
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: P165A_ARATH
Sequence: MRVKLFQLRGMLSGSRIL
What is the function of this protein?
Regulatory peptide encoded by the primary transcript (pri-miR165a) of the microRNA miR165a that enhances the accumulation of its corresponding mature miRNA.  Acts as a transcriptional activator of its corresponding pri-miRNA.  Addition of synthetic miPEP165a increases the abundance of miR165a, with consequent increase of root length.
What are the official names of this protein?
Peptide encoded by miPEP165a.
Protein: BBX_HUMAN
Sequence: MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRDLPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQTSALFQFAEISSNTSQLGGAEPVKRCGKSALFQLAEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSAKENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHMCHPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSKEKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCHRKIETCGSRKSERSCKGALYKTLVSEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESWTFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKKKTGNVSSEPTKTSKGPFQSQKKNLFHKIVSKYKHKKEKPNVPEKGSGDKWSNKQLFLDAIHPTEAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTADGRVSPAGGTLDDKPKEQLQRSLPKATETDCNDKCSHNTEVGETRSSTPEMPAVSAFFSLAALAEVAAMENVHRGQRSTPLTHDGQPKEMPQAPVLISCADQ
What is the function of this protein?
Transcription factor that is necessary for cell cycle progression from G1 to S phase.
What are the official names of this protein?
HMG box transcription factor BBX, Bobby sox homolog, HMG box-containing protein 2.
What are the subcellular locations of this protein?
Nucleus.