PharMolix/UniProtQA huggingface dataset:
Protein: ARK1_YEAST
Sequence: MNQPQIGTYNVGTQLTVGSHQVEIIKYLTSGGFAQVYSALINPPDPHSNSSVACLKRVIVPDKPSLNTLRAEVDAMRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQVTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCGIIRPPRNSQELSYVQQDILKNTTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSGKFEFPLYPNYSEQLKGLIRDILVQDPRHRPNVYQLLKRISIMQNVPCPINDIQVVQAPSSHLNLTELHQLSATQNILSLNSPTTMENTMPNATFQISMADNTTTAQMHPNRKPSQIAYDASFSNSAKGSQPLFDKSQNMYHALDPPLVEPLASSVSNNDNELKANSATKLKQAIVSEAHTFRQNNSIDFPLQNIIPQYEDSSSSSDESYSGDVDELKKTRSLGSYSTRGNIKKNQSVKESLTSSSLPGTSFTPTSTKVNLKHENSPFKSTFVNTIDNSKDDLNKPSYEDLDVSKQNLKNSIQQRMIDKLNSSEESFNARKMSKVKLHEKGEIDKPTMLKSSGPISKDKKTKPTPPPKPSHLKPKPPPKPLLLAGRKLSLDK
What is the function of this protein?
Involved in regulation of actin cytoskeleton organization and endocytosis.
What are the official names of this protein?
Actin-regulating kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: Y1817_PELTS
Sequence: MLVVLLLIGMAAHSSLIVIAACILLILKLTNVNFIFSLLERRGLEMGLTFLLLSILVPLASGKASWQEIISSLASFSGLLAVAGGALATSLNTRGLNLLKADPEIVFGLLLGSILGIVFLHGIPVGPLMAAGITALLMQLARIFKP
What are the official names of this protein?
UPF0756 membrane protein PTH_1817.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MODB_ECO57
Sequence: MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
What is the function of this protein?
Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Molybdenum transport system permease protein ModB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HUTI_STRP3
Sequence: MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITNDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYLFYFFATNLIHQVYKKGQLTVDRGRIL
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_BUCAI
Sequence: MEVQRNFFIFAFLFVSFLLWQAWQSQMFLNKKTNEKIDPIFHFIDVKKNKKKIFIKNDVISLVVNMYGGDVEEASLLAYKDTLYSSRPFKLLETGSDFIYQAQSGLIGKDGPDSSINDSRPLYSANKNFFVLGPNEKELRVPIKWLSKNGVIYKKTFILKPNRYDVQIEYDVYNPSKESLNMNIFGQIKQTINLPKKRNVYSGNFALQTFRGAAYSSDDNKYEKYKFDMIANNKNLHIMTESGWIAMLQQYFAVAWIPDNLGKNTIYTSSLDHDTAVIGYKSPIINIPPNSRSIIKSKLWIGPKIQKEMKLVAPNLDLTVDYGWLWFLSQPLFKLLTILYSIIGNWGFSIILITFIMRGLTYPLTKAQYISMAKMRALQPKIQEIKEKFSKDKQRISQEMILLYKKEKINPLGGFLPIFIQMPIFLSLYYMLIGSVELRHAPFLLWIHDLSSQDPYYVLPVIMGLTMFFIQKISSTNHISDPLQKKIMNFMPVIFTAFFLWFPSGLVLYYIISNLVTIIQQKFILSNLEKNR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KLH17_HUMAN
Sequence: MQPRSERPAGRTQSPEHGSPGPGPEAPPPPPPQPPAPEAERTRPRQARPAAPMEGAVQLLSREGHSVAHNSKRHYHDAFVAMSRMRQRGLLCDIVLHVAAKEIRAHKVVLASCSPYFHAMFTNEMSESRQTHVTLHDIDPQALDQLVQFAYTAEIVVGEGNVQTLLPAASLLQLNGVRDACCKFLLSQLDPSNCLGIRGFADAHSCSDLLKAAHRYVLQHFVDVAKTEEFMLLPLKQVLELVSSDSLNVPSEEEVYRAVLSWVKHDVDARRQHVPRLMKCVRLPLLSRDFLLGHVDAESLVRHHPDCKDLLIEALKFHLLPEQRGVLGTSRTRPRRCEGAGPVLFAVGGGSLFAIHGDCEAYDTRTDRWHVVASMSTRRARVGVAAVGNRLYAVGGYDGTSDLATVESYDPVTNTWQPEVSMGTRRSCLGVAALHGLLYSAGGYDGASCLNSAERYDPLTGTWTSVAAMSTRRRYVRVATLDGNLYAVGGYDSSSHLATVEKYEPQVNVWSPVASMLSRRSSAGVAVLEGALYVAGGNDGTSCLNSVERYSPKAGAWESVAPMNIRRSTHDLVAMDGWLYAVGGNDGSSSLNSIEKYNPRTNKWVAASCMFTRRSSVGVAVLELLNFPPPSSPTLSVSSTSL
What is the function of this protein?
Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes.  The BCR(KLHL17) complex mediates the ubiquitination and subsequent degradation of GLUR6.  May play a role in the actin-based neuronal function (By similarity).
What are the official names of this protein?
Kelch-like protein 17, Actinfilin.
What are the subcellular locations of this protein?
Postsynaptic density. Synapse.
Protein: THIC_NEIG1
Sequence: MTTPKKTAKISGNEARELSDLSEDIGIRFKYQNSERVYLQGSRDDIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGAYGDPAAHIDLKQGLPHIRTAWLDERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKAGRNVTQLHYARQGIITPEMEFAAIRERMKLDELFRRPEYAKLLKQHTGQSFGANIPTRPDQITPEFVRQEIAAGRAIIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQTLEKTGGIAEDLTWDLFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEFVKKGAKIYS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: PSBU_SYNY3
Sequence: MKFISRLLVACSLLIGLMGFLGADLAQALTPNPILAELNAVDAKLTTDFGQKIDLNNSDIRDFRGLRGFYPNLASEIIKNAPYDTVEEVLDIPGLSETQKSRLEANLGSFTVTEPSIELTSGDDRINPGVY
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.  May modulate the Cl(-) requirement for oxygen evolution.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: OTC_ACIC1
Sequence: MIRHFLADDDLTPSEQAAVLDEAARLKKDRYAARPLTGPRSVAVVFEKPSTRTRVSFEVAITELGGQPVVLDAVGSQLGRGEPIEDTARVLSRYVAAIVLRTFGHDRITTLARYATVPVVNALSDAYHPCQALADLLTIRERKGGLDGVRLAYVGDGNNVACSLLVAGAMAGLHVTVASPAGYQPPPAVVARAAEIGEQTGGRVEVVDDPRTAARNADVLYTDVWTSMGQEEETAARRRAFAGFTVDDDLLALAADDAIVLHCLPAHRGEEITASVLEGPQSAIFDQAENRLHTAKALLSFLLDAAGGRGIP
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_EXIS2
Sequence: MAQSFKRVFLVVMDSVGIGEAPDAEQFGDLGAHTLGHIAEQRNGLNMPHLAQLGLSHIEPVQGVSADAAPIASFGKMEEVSAGKDTMTGHWEIMGLRIDTPFRVFEKFPEDLIGRLETFSGRKIIGNKPASGTEILDELGQEHVDTGALIVYTSADSVLQIAAHEEVVPLEELYRICEYARDITRDDPYMLGRIIARPFLGEQGAWVRTSNRHDYALKPFDRTVMNELETAGLDVISLGKIADIFDGEGVTDAIRTKSNMDGMDQLVKQLDRDFTGLCFLNLVDFDALFGHRRDPQGYGQALEEFDARLLEVFERLQEDDLLIITADHGNDPVHPGTDHTREYVPLLVYSKSGAAKDLGIRSTFADLGATVADNFNVKMPAHGKSFLSEL
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2H2_BOTMO
Sequence: SLFELGKMILQETGKNPAKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYRYNYLKPFCKKADPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) homolog that lacks enzymatic activity.  Shows high myotoxin activities (PubMed:16442348, PubMed:9637370, PubMed:31748642).  Also shows neurotoxicity, since it induces muscle paralysis when tested on mouse phrenic-diaphragm preparations (PubMed:16442348, PubMed:23810946, PubMed:26457430, PubMed:30679550).  Displays edema-inducing activities (PubMed:9637370, PubMed:16442348, PubMed:26457430).  Also displays antimicrobial activity against E. coli and C. albicans, as well as antitumoral activity against some human and mice cell lines (PubMed:16442348).  In addition, it is effective as parasiticidal agent against Leishmania sp.  and S. mansoni (PubMed:16442348).  It also disrupts negatively charged liposomes in a dose- and temperature-dependent manner and shows toxicity by intraperitoneal route (PubMed:16442348).  In contrast to other phospholipase A2-like toxins, this myotoxin does not require fatty acid binding to be active (PubMed:29287778).
What are the official names of this protein?
Basic phospholipase A2 homolog myotoxin II, MjTX-II, svPLA2 homolog, Basic phospholipase A2 homolog 2, M-VI.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ANMK_SHESW
Sequence: MKNAYYIGLMSGTSMDGVDAVLVDFSGPQPQLICSHTEAIPSHLLKGLQRLCLPGADEINRLGRLDRNVGQLFALAVNNLLAKCNIAKEDIIAIGSHGQTVRHMPNLEVGFTLQIGDPNTIATETGIDVIADFRRKDIALGGQGAPLVPAFHQQTFAEIGKKRIILNIGGIANVTYLPGTSEHVLGFDTGPGNTLIDAWIQHVKSEPFDKNGEWAASGKTNPDLLAQLLSHPYFSLAYPKSTGRELFNQAWLEQQLSPFNHLDEEDIQSTLLDMTCHSIARDVIKLSPEGELFVCGGGAFNTQLMQRLAALLPGYKLDTTSALGVDPKWAEGIAFAWLAMRNHLGLPANLPAVTGASREAVLGGRFSAK
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: HEM3_LIMRD
Sequence: MTNKVIVGSRKSKLAMAQTELVIASLEKIFPDIKFEIKNVITEGDRNRHVSLAKIGGKGVFVKEIEDELKDGTIDFAVHSLKDVMPILPEELVLGAFPKRVSPYDCLVSRKNLSSLNDLPKGARIGTNSLRRQGQLLSIRPDLKIIPIRGNIDTRLRKIDTEALDGIILAEAGLTRLNIDLSSYHVLDLQNYIMPAVGQGCLAIECRKNDTRIRKMLDQINDEESAYCVQVEREFMRELGGSCNFPIGGHAYAKNGQILFDGLIASPNGEHVIKETKIPANNSGVGKKVADQLLAKDKFGIIEGE
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: NUOH_PHEZH
Sequence: MMDPAATSFWATPVGWTLVTAGQILAVMIWILLSLAFLLLADRKIWAGVQMRKGPNVVGPFGLLQSFADFLKFVLKEIVIPSGADKTVFLLAPLISFTLAFAAWAVIPLAPGWVVSDINVGILYLFAISSLGVYGIIMGGWASNSKYPFLGSLRSAAQMVSYEVSIGFIIITVILLAGSMNLQQIVASQTGGFWNWYVFGGPGGLAKLPLLLVMVPMAVIFFISGLAETNRPPFDLPEAESELVAGYQVEYSSTPYLLFMIGEYANIVLICAMTTILFFGGWSAPFPSDFTDSWAPTAASFYYFMWFFLKVIFFFFLVSMAKAIVPRYRYDQLMRLGWKVFLPFSLVCVALIAAWRVFGPAAAA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEF11_NPVAH
Sequence: MSKKENIIGNKNRTQKYNNACLTRSDVYALVKETINKRKHDGEFCNITAHIFDEGFEQQKEYIREKLSTASIVTDCRQNRKRLALHRKKIESIFNIHTSLQEEFNSCSRRYNGSPNLE
What is the function of this protein?
Involved in late/very late gene activation.
What are the official names of this protein?
Late expression factor 11.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-11 family.
Protein: ATPZ_PSEPK
Sequence: MEIRTPNRLPFHRWAVFPVLLAQFVVLLLATLVLWQWKGSVSGYSGLCGGLIAWLPNVYFAWKAFRFSGARAAQAIVKSFYAGEAGKMILTAVLFALTFAGVKPLAPLAVFGVFVLTLLVSWFAPLLMNKRLSRP
What is the function of this protein?
A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
What are the official names of this protein?
ATP synthase protein I.
What is the protein family that this protein belongs to?
Belongs to the bacterial AtpI family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMT_CAUVN
Sequence: MRIAFLGTPDFAVTCLAELVASGHEIVCVYSQPPAPRGRGQDLKPSPVHAFAEGLGLPVRTPVSMKTPEEIAAFQALDLDAAVVVAFGQILVKDVLEAPKHGCFNLHASLLPRWRGAAPIQRAIMAGDAVTGVQVMRMSEGLDEGPILMSQQVAIADDDTAASLHDKLAAVGARLLPVALAAIEREVVQETPQAEDGVTYAKKIKSAEARIDWTRPAAEIDRHIRGLSPFPGAWFEAPSEKGPVRVKALLSRVEAASGVAGTTLDDALLIACGEGSIRLLKAQREGKGVQDAQTFTRGFPIATGTVLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: APOA1_PIG
Sequence: MKAVVLTLAVLFLTGSQARHFWQQDDPQSPWDRVKDFATVYVDAIKDSGRDYVAQFEASALGKHLNLKLLDNWDSLGSTFTKVREQLGPVTQEFWDNLEKETEALRQEMSKDLEEVKKKVQPYLDDFQNKWQEEMETYRQKMAPLGAEFREGARQKVQELQEKLSPLAEELRDRLRAHVEALRQHVAPYSDDLRQRMAARFEALKEGGGSLAEYQAKAQEQLKALGEKAKPALEDLRQGLLPVLENLKVSILAAIDEASKKLNAQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL18_STAAE
Sequence: MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: AROC_RHIME
Sequence: MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGIRFTLAEVQAWLDKRKPGQSRFVTQRREDDLVKVLSGVMLDDDGETMISTGTPISMMIENTDQRSKDYSEIAKRYRPGHADYTYDAKYGIRDYRGGGRSSARETAARVAAGAIARKVVPGLVVRGALVQIGKHRIDRSNWDWAEVNNNPFFAPDPAIVPVWEEYLDGIRKAGSSIGAVVEVVAEGVPAGIGAPIYAKLDQDIAANLMSINAVKGVEIGNGFAAAEISGEENADEMRIGAQGEPVFLSNNAGGILGGIATGQPVVARFAIKPTSSILTERRSIDSDGKEVDVRTKGRHDPCVGIRAVPIGEAMLACAIADHYLRDRGQTGRLK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RISB_CLOB6
Sequence: MKIYEGKLTAEGLKVGIIVSRFNEFITSKLLAGSIDCLKRHGAKEDNIEVCWVPGAFEIPVIAKKMASKGKYDAVICLGAVIRGATPHFDYVSSEVSKGVAHVSLDKEVPVIFGVLTTNTIEQAIERAGTKAGNKGYDAAMSAIEMSNLMKILD
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RL29_COLP3
Sequence: MKVSELKAKSIEELNAELLELLREQFNYRMQASTGQLAQTHLLRIVRRNIARVKTIITEKAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: POL2_BBWV2
Sequence: MRPELVAVLDRYFSEIISCFFLGWLLNFLLVWFCSTKSTFLLWSVFLYICYYILRIEFAYIVAPFLKTIYTNSSQYHTVDWAYAYTALPKGLWEQITDYNYCYNFPPPRVEGFVSDFSPRFTLKELEIMNEANITPVHTIPKDTLLKRASDYKLAVESKKSILPRVQDLYEMDKWHNLRSKLSKNAPSYVTTSEIAVGAMSGAGNTKLAIPVVEKYTEEVADDRLPDRVRAKADQIMVAAIELVADGFASVNSDVTMAGALYDKRHKTIASSFKGAFASRASGVPSHVIYFPMHRVPACDDPNTTLELSMVSRDSDFDEGYTLANISARTLYVRAKGPEKVTETRHLLKAKTEDVVKARQFASEAQVVFATPRLFPEVNLDNYNLPGPSNAQQTEAITTDRGILFPKPKFKGNEVVLNYTGSGKIRNVGSQRFETKKNATGEQFVRSVDDLGCLSDEDGKDYRYGQGLMEEDVLNVQTNNFAIESATETMRLLFSGYASIPLNVIPGTKITVAYLNELSKHSAVHTGLLNMLSKIPGSLKVKINCQVAPTCGIGLAVSYVEGNESANLGSSLGRLLGIQHYKWNPAIEPYVEFVFKPFSCADWWNMHYLGSFKFAPVVVIQTLSKWLNAPKVDARISFAIYYEPTVVLPKQIATLEHAPAFMFRKEVGTLAFKQGERVAYSFEVNLGKPQTDGKEVTSTFASSYCGLSQYMQSDVILDFTLMSSPMIGGTFSIAYVAGAYIEKVGNMQILDSLPHIDFTFSSGSKSTRSVRFPKEVFGVYQALDRWDLDSARGDDVSGNFVLYQRDAVSSALEGELTFRIAARLSGDISFTGVSAGYPTTITRIGKGKTIGRSLDPEIRKPLRYMLGQAHATPKDFSSVRFVMGHWKYRAGLYPGSKSDEDIHPFSLKMRLDGSKSSENFEIIHSPFVRLLQNCAWMRGTLRFYVVARASSDYMSYRRTSQLTVSAHENSLSSNQFYSGVLTSPSGELSFSREVVGPVDGFASMGWNVRGSKKFYKIHVEMGNVHEYDTVVLYGQFDSNVEFAGQRKGGHYLLEKETPIFKTIKY
What is the function of this protein?
Together with the large capsid protein, forms an icosahedral capsid (T=3) enclosing the viral positive strand RNA genome, with a diameter of approximately 300 Angstroms (By similarity).  The capsid is formed from 60 copies each of the large and the small capsid protein.  The small capsid protein forms the turrets at the fivefold axes of the viral particle (By similarity).
What are the official names of this protein?
RNA2 polyprotein, 119kDa protein, Genome polyprotein M.
What are the subcellular locations of this protein?
[Movement protein]: Host endoplasmic reticulum. Host cell junction, host plasmodesma. Note=Assembles in tubules that are embedded within modified plasmodesmata. SUBCELLULAR LOCATION: [Large capsid protein]: Virion. SUBCELLULAR LOCATION: [Small capsid protein]: Virion.
Protein: IMPA1_XENLA
Sequence: MEDRWQECMDFLAVSIARKAGSVVCAALKEDVSIMVKTSLAPADLVTATDQKVEEMIISSIKEKYPSHSFIGEESVAAGAGSTLTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVHKQVEFGVVYSCVEDKMYTGRKGKGSFCNGQKLQVSGQKDITKSMIITELGSNRNPEFIKTVSLSNMERLLCIPIHGIRAVGTAAVNMCLVATGGADAYYEMGLHCWDMAAASVIVTEAGGTILDATGGLFDLMSCRIISASSREIAERIAKELQIIPLERDDGKSTNS
What is the function of this protein?
Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain.  Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
What are the official names of this protein?
Inositol monophosphatase 1, IMP 1, IMPase 1, D-galactose 1-phosphate phosphatase, Inositol-1(or 4)-monophosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOGC3_ARATH
Sequence: MWSSIENMKANLHKIVLDVHEDDEEEDDLHKYGSANGVSNSDRRNSSGFRSVSRYSISNGIESPAHHEIERYKAEIKKLQESESDIKALSVNYAALLREKEDQISRLNQENGSLKQNLTSTSAALKEARTDISRGSNNYAIKGNNDQSPNRLHKSVSHLKSPNHMSNGKGKDTDSFIKEKDLADMLEDRTKSMAAVQATELAKEREKLRDFQLSLQEERKRSESFKEELESMRLDKNKTSMEISKMRSELDAKLLEIKHLQMKLTGQESHAIGPGMEHLKEVNKALEKENNELKLKRSELEAALEESRKLTNSKVFPDATESLTRHPSTLDKEKPESFPGKEEMEQSLQRLEMDLKETQRERDKARQELKRLKQHLLEKETEESEKMDEDSRLIEELRQTNEYQRSQISHLEKSLKQAISNQEDNRLSNDNQIRKLKDTVDDLNQKLTNCLRTIESKNVELLNLQTALGQYYAEIEAKEHFERELAMAKDELMKLSARLKDSDERLESSNKEKEDVTSKLLHAEKVAAEWKNRVTKVEEDNAKVRRVLEQSMTRLNRMSMESDYLVDRRIVIKLLVTYFQKNHNKEVLDLMVRMLGFSEEDKERIGAAKQGGGKGVVRGVLGFPGRFVGGILGGKSAELHANAASDNQSFADLWVDFLLKDAEERERREAEEAAASKAKQDSERTRQEAALHDSEFSTVPLRSSESNQRLSR
What is the function of this protein?
Golgi matrix protein playing a role in tethering of vesicles to Golgi membranes and in maintaining the overall structure of the Golgi apparatus.
What are the official names of this protein?
Golgin candidate 3, AtGC3, GRIP-related ARF-binding domain-containing Arabidopsis protein 1.
What are the subcellular locations of this protein?
Golgi apparatus. Endosome.
Protein: TUSA_BUCA5
Sequence: MKKNIILNLIGLRCPEPIMIIRKTIRDMKDNEKILILSDDPATKRDIPNFCYFMEHKLLKNEIKVKPYRYLLKKGL
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.