PharMolix/UniProtQA huggingface dataset:
Protein: SYC_PROM1
Sequence: MSLKFTNTLSKKKEDFISINPNQVKIYCCGVTVYDLCHLGHARSYLNWDVLRRFLIWKGFEVKFVQNFTDIDDKIINRANKEGCSTDELSERNIDEFHKDMDTLSILRPTSMPRATKCLHQIINFIEELEQKKVAYSSNGDVYFSVNKHKNYGKLSGREIENQIDNAAGRLKTNQKESKKNSLDFALWKKSNSGEVSYSSPWGNGRPGWHIECSAMVKQELGESIDIHLGGSDLIFPHHENEIAQSEACNGKELAKYWLHNGMVNVGGEKMSKSLGNFTTIRSLLEEGISPMTLRFFVLQTNYRKPLDFTQEALKAASKGWERLNNCLSFGYIYKIKDQAKNEIILDKPIKKSANTNLDKESFKLLSDFERYMDDDLNTSGALSILFELSQPIRKIINFLKEKDINEVDQDELNQVFYKWELLSELAAVLGLKVNLNHENPKNNPELDTNKIEELIKKRSLAKANKDFLLADKIRDDFKNIGIDLIDKPKGVTEWKQLSD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLT_PHOLL
Sequence: MNASSVVQPLLTRGMKAVLVSQFFSAFADNALLFAILAQLKAQFYPDWSQPILQIVFVLAYILLAPFVGQIADRFPKDRVMLFANSFKLLGAFTICLGYDPFLGYALVGVGAASYSPAKYGILVELTDGDRLVKANGLMEASTIIAILTGSVVGGFLSDWNLAIALLVCALMYGIAVVANFFIPRLSAVRRDKGWNLKKMLTDFASACCILWHNKGARFSLIGTSLFWGAGITLRFLLVLWVPVVLGISDNSTPTILNVMVAVGIIIGAGAAARFITLKTVHRCMPAGVLIGVMVVIFAVQHSIWASYVLLIILGIFGGLFIVPLNALLQESGRQTIGVGYAIAVQNLGENIAMLLMLGLYSLVIKIGVPVVTTGIGFGTLLALTITSLWIWNRFQRN
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPF2_BRUSI
Sequence: MDATFWAFIALVIFVAIVVYMKVPGMIGRTLDERADRIKKELEEARTLREEAQQLLAEYHRKRKEAEKEAGDIVASAEREAKALLEEAKRATEEYVARRNKLAEQKIATAETDAINAVRASAVDLAVAAAGSILAEKVDAKAAGNLFNDALAQVKSHLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: VAPC6_MYCTU
Sequence: MAAATTTGTHRGLELRAAQRAVGSCEPQRAEFCRSARNADEFDQMSRMFGDVYPDVPVPKSVWRWIDSAQHRLARAGAVGALSVVDLLICDTAAARGLVVLHDDADYELAERHLPDIRVRRVVSADD
What is the function of this protein?
Toxic component of a type II type II toxin-antitoxin (TA) system.  An RNase.  The cognate antitoxin is VapB6 (By similarity).
What are the official names of this protein?
Ribonuclease VapC6, RNase VapC6, Toxin VapC6.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: IQD8_ARATH
Sequence: MGGSGNWIKSLITNKKNITDDQEKNIKKKWKLWRTSSEGLISSSKGFKSRGGSYGTPSLGSDPPSFSADDSFTAAVAAVIRAPPKDFFLVKREWAATRIQAAFRAFLARQALRALKAVVRIQAIFRGRQVRKQADVTLRCMQALVRVQARVRAHCNRGPSDGQELEKPSDQQKDDPAKQAEKGWCDSPGSINEVRTKLQMRQEGAIKRERAMVYALTHQPRTCPSPAKASKQGSVKKNNGSCKSSPGWNWLDRWVADRPWEGRLMEGPTNSSENARKSESSVSEHDTVQVRKNNLTTRVLARPPPMSSSATSSESSSTSQSPVPFSGSFLEEGGYYRKPSYMSLTQSIKAKQRRSGSSSSCSKTPFEKKQSMSYNGDVNVRRSAGSDPLNNQWTDLYPPAQVTGRHMWAKSQRG
What is the function of this protein?
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).  Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity).  May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
What are the official names of this protein?
Protein IQ-DOMAIN 8, AtIQD8.
What is the protein family that this protein belongs to?
Belongs to the IQD family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Nucleus envelope. Note=Recruits calmodulin (CaM2) to microtubules.
Protein: DSRB_ECO27
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNEAGHQDGIFVEKAE
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: RS6_CAMJ8
Sequence: MKHYEVLFILKPTLTEEEVNAKLEFVKEVLTKNGAEIETVVPMGTRKLAYKIKKYERGTYFVIYFKAPTNLIAELERVLRITEEVIRFLIVKYENKKEIAAWEKLSHGIKQSKKEIKPLDAPEIQ
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ILVC_TOLAT
Sequence: MANYFNTLNLRQQLEQLGKCRFMNRDEFASECDFLKGKKVVIVGCGAQGLNQGLNMRDSGLDVSYALRAEAIAEKRKSFKQASENGFTVGTYEDLIPTADLVVNLTPDKQHTSVVKAVMPLMKDGAALGYSHGFNIVEEGTQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGDGLAIAKAWAAATGGHRAGVLQSSFVAEVKSDLMGEQTILCGMLQAGSILCYEKMIADGIDAGYAGKLIQFGWETITEALKQGGITAMMDRLSNPAKLRAFELAEEMRVLMRPLFRKHQDDIISGAFSSGMMADWANNDADLFRWREETGASAFENAPAFDGAIAEQEYFDNGILMVAMVKAGVELAFETMTESGIIAESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANAAVPLLKAHIMPKVGTDVIGKTLSVKDNGVDNVTLVQVNEIIRNHPIEQVGKVLRGYMKDMKRIAVGG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: GL25_ARATH
Sequence: MASFATHLVVVVTMLFVAMASAEMLQDVCVADLSNAVKVNGYTCKDSTQITPEDFYFKGLANIAATNTSTGSVVTGANVEKLPGLNTLGLSMSRIDYAPNGLNPPHVHPRASEIIFVLEGQLYVGFVTTAGKLIAKNLNKGDVFTFPKGLIHFQKNIANSPASVLAAFDSQLPGTQSLVASLFGALPDDILAKSFQLKHKQVKKIKLRYAPKK
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Probable germin-like protein subfamily 2 member 5.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: PYRG_DEIRA
Sequence: MKYIFVTGGVVSSLGKGVASASLGALLRARGYKVTAVKIDPYINIDAGTMRPYEHGECFVTASGAETDLDIGNYERFLDLDIPAGSNITTGQVYQEVIRKERAGDYLSQTVQVIPHVTDEIKRRIRAAGESAGAEIVLIEVGGTVGDIESLPFLEAIRQFRFDEGDDNVLYLHLTLVPYLGTSNEFKTKPTQHSVAALRSYGISPDIVMVRSKDKLPAEITRKIAAFTSVRENRVFSSYDVEHVYQVPLALEEQGLGKAVEELLGLEGTHPRLGVWTDAVRTIKHPKQQVTIAIAGKYTAMPDAYLSLMESLTHAGIANDARVNIKWVNAEQLAEAGAGELEGQFADVDGILVPGGFGIRGIEGKVKAAEYARTHGVPYLGICLGMQIAVIEYARHVAGIEDANSAEFDEYAKNKVIDLMPEQLEVAGMGGTMRLGDWPMELRAGTKIAELYGVPQGGTVKERHRHRYEVNPAYVEQLEAAGLTISGVTPGVEGRGAGLVETVEIADHPFFVALQAHPEFKSRPMRPSPPFAGFVKAALEHQQQ
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RIBA_NEIMA
Sequence: MSELLNYVASCRLPTEWGVFTMHGFEEAGGQEHVALTVGDCSDGNPVLTRIHSECLTGDALFSKKCDCGPQLEAAMKAVQAEGRGIIVYLRQEGRGIGLINKIRAYHLQDQGMDTVEANVALGLPVDARDFRLAQSIYEYLGIRSVKLLTNNPEKIQTLKDAGINVVERIPLHVGENLENKRYLQTKADKLGHLMSE
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: BLNK_CHICK
Sequence: MDKLNKLAVPAGEKFRKLQKMVHDIKKNESGIINKFKKFQNEQVALICKTGKDTWDRLKKKPPPSLPRRDYASEHADNEEEQWSDDFDSDYENPDGHSDSEMYVVPSEENPDDSYEPPPSEQEKKKIPSSFPISRGEYADNRTSHHQLPPINKPLPSTPSSALPRPKKPSLPSPAAKPKLPLKPRECSDDEDNYIVPVDNDDDNYIEPTESSTPPPAKPPVNRFMKPPAKSALPTPPKPSLASDMQEVYEVPEEEEELSPPPVTRFTKPLPATRAQNAEHSHMHSMTRESPKLDASRNILPLPRNRLHPKTDHEANNNDENHSFSNTQESKFPPGAAPSPLPRALKKTSNAVNPAKPCLPSRDTFTVNEDKPTAADRRRGSSHEFPLPPLPSGTPKSSLQKPLVLPKVPEAPSRALGTSPHSSISSISSTADQDAGVHSKAWYAATCDRKTAEDALYRSNKDGSFLIRKSSGQDSRQPYTLVVFYNRRVYNIPIRFIESTRQYALGREKCGEERFDSVAEIVENHQHTSLVLIDSQNNTKDSTKLKYIVRVS
What is the function of this protein?
Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development.  Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK.  Modulates AP1 activation.  Important for the activation of NF-kappa-B and NFAT.  Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes.  However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling.  May be required for the RAC1-JNK pathway.  Plays a critical role in orchestrating the pro-B cell to pre-B cell transition (By similarity).  Plays a critical role in B-cell development in the bursa.  Plays an important role in BCR-induced apoptosis.
What are the official names of this protein?
B-cell linker protein, B-cell adapter SH2 domain-containing protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=BCR activation results in the translocation to membrane fraction.
Protein: YOHJ_SALPB
Sequence: MSKSLNIIWQYIRAFVLIYACLYAGIFLASLLPITIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAISTLVVFVVVSWSSHLIHGERKVVGQKGTKK
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS6_CHLL2
Sequence: MEKTKLYECTVIIDGGLQDEAIAAAMEMVQKVITEKGGSISSVLEVGRRKTAYPINKKTIGYYAHIEFTAAAPVIGAIEKVLRYEEDLLRYLIIHLTSALLEMRKRVEKYSVVIGSPEDTAAAESDDSGKDAK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: SIP5_BOTFB
Sequence: MGQHQSRDDSHGGDRHRHHDAGTSGPTSPSDHDPYPSRTGRGSRRNLVASIVGGGSNNELPERKETAAERQMRRLERERVARVEERERSIREEHVDGGYLVTMGVYTGPEDFNKAIVRQLMIERRVAPFWRGLEDYESDWTEHQLVAAGRGLPIPAADEIPSEDSARPHSSNSTNAPSSNLQNLTVPIASRSQSASYDTSVGRSPSHSSFNTSSPTSPLNAPATSTSLLRPRAKTLGLKSSSKEPSASDSAPREIQLPRDSQVNGQAIEAFLYKDAVECSICLIFYPPYLNRTRCCDQSICSECFVQIKRPDPHTPEHHGPPQPAPDQAEDTEMLVSEPAACPYCQRPEFGVTYEPPPFRRGLVYAKPSRELANFSSAMSSSSSITSPPITSPGLAPRVDNRRRATSLSANDSNVITTDRIRPDWSAKLEAANLRKAKKNAAASALHAAAYVLPGTSENRSYVFGRSRFGRNRSDPDNSGSATPSNRDTSSRTAAESSGQARREGRDSHAARRTRDVEDMMMAEAIRLSIVAEEERKKKAEKEAAKEAAKNAKKQAKEDKKKEKKERKSIYGTNGHSASSSMLNLGNSLAATLTGRRRGDSVASNLATEVTPEEVEEPLQGKGKGVAHPYLGNDGSATDNGLLGTQHLDPSTSSSLLETHQSIPSPTSPDKPSHLRQMSTASSASSSVAESGNGTNPQGSSTSIESPGVTDTNEGNEDGDTGAESMFNFRSLTAMIEKENDNEKTDAVHVENAHEASGSRRGSPDETASQDMDVSMETLRPRDSPQQPKPDHHVPMGLQMPAPKIDTSIVTPQLTLTPDTPALMSPTEENGKQLGSNLQNLSNNEISQ
What is the function of this protein?
May negatively regulate the snf1 kinase.
What are the official names of this protein?
Protein sip5.
What is the protein family that this protein belongs to?
Belongs to the SIP5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTA_PASMU
Sequence: MSNTHFHCRKLKNKLMLTLSFLAVFFGLFWLCWILFTLITKGIPALSLELFLEKTPGPGEKGGLLNAIIGSTLMITVSTLIGTPIGILAGTYLAEYGRYSQLTKVTRFLNDVLLSAPSIVIGLFIYAIYVSQVKHYSGWAGAFALAIIIIPVVVRTTDNMLNLVPNNLREAAASLGCPQWRVITMICYRSARAGILTGVLLSIARISGETAPLLFTALSNQFTSFDMNGPMANIPIVIYQFAASPFQDWNELAWAGATLITLFVLLLNIFARIFFPQKSK
What is the function of this protein?
Part of a binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphate transport system permease protein PstA.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBIE_ECO7I
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: LEUC_RHOBA
Sequence: MSDASSTAPSQAGATSQSTGSRTLLDKIWDQHLVHAPESGPAIIYIDLHLVHEVTSPQAFEGLRINNRPVRRPERTIATPDHNVPTSDRSLPIADPISRKQIETLRENCKEFGVQLFDIDDVRQGIVHVIGPENGYTQPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLLQFKPKTFELRVDGELARGVTAKDMILYLIGQIGTAGGTGYVLEFTGDAVRNLTMEERMTVCNMSIEAGARAGMIAPDQTTFDYLRGRPECPADFDAAVEAWKKLPSDPGATYDRSNLYKGSDIRPQVTWGTNPGQVCSVDSVVPSPGDSTDVNVQKSTASALQYMDLKAGTPITEIEINRVFIGSCTNARIEDLRAAAAVIKGHHCSDKVNAMIVPGSGKVKLQAEEEGLHKVFTDAGFDWREAGCSMCLAMNPDKLAPGERCASTSNRNFEGRQGKGGRTHLVSPAMAAAAAIKGHFVDIRDWDYR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SYFB_SACS2
Sequence: MVTIVLNKYKLLNKIGIGQQKLEDLLFNLKSEIKPVDESNIEIEINADRLDLLSSDGIARAIKGLLEKELGEAKYDITDTEYKLIVDNVRTRPYALAAVIYNAKIDLQELIQFQEKLHSTIGRKRKKVAIGIHDLKKIDSKRIEYREVPLSYKFIPLYEKEELTISEVLEKTEQGKLYGNISISNGVSPAIVQEDGEVLSIPPIINSDKTKLDESTKDLFIDVTGTSFEAVAQTLDIIVSNLAEAGGTIGRVKVIKTDNSFQQSSPLLIHKIQNVREEYANKILGIKISEEEICKHITRMRMNCNVENGIIRVTVPQYRVDIINEIDIVEDIAMSIGYNNLEPSKYISTNYGSYDYLTLLERKMRELSIGAGFVEVFNFVLIKNEKILDSKYVKILNPISEEYNAVRNSLIPILLDFLSKNQHAKFPIRIFETGDVVIYDSSTDTGFRNDKRAAYAIMDNKVSYEDVQAPIHYILKTLGIEVNYKEENNDIFIEGRSASIVYENEKIGVIGEINPDVLIRFGIEYPTVIAELYITEIAKKLNKR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_FBNY1
Sequence: MASKWNWSGTKGRRTPRRPYGRPYKSSVPTTRVVVHQSAVLKKDEVVGTEIKPEGDVARYKMKKVMLTCTLRMAPGELVNYLIVKCNSPISSWSAAFTSPALLVKESCQDMITIIAKGKVESNGVAGTDCTKSFNRFIKLGAGITQTQHLYVVLYTSVALKAVLEHRVYVEV
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the nanoviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: VEMP_SARS2
Sequence: MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNIVNVSLVKPSFYVYSRVKNLNSSRVPDLLV
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis (By similarity).  Regulates the localization of S protein at cis-Golgi, the place of virus budding (PubMed:33229438).  May act by slowing down the cell secretory pathway (PubMed:33229438).  May interfere with tight-junction stability by interacting with host MPP5.  This would result in disruption of epithelial barriers, thereby amplifying inflammatory processes (PubMed:32891874).
What are the official names of this protein?
Envelope small membrane protein, E, sM protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: EGS1_OCIBA
Sequence: MEENGMKSKILIFGGTGYIGNHMVKGSLKLGHPTYVFTRPNSSKTTLLDEFQSLGAIIVKGELDEHEKLVELMKKVDVVISALAFPQILDQFKILEAIKVAGNIKRFLPSDFGVEEDRINALPPFEALIERKRMIRRAIEEANIPYTYVSANCFASYFINYLLRPYDPKDEITVYGTGEAKFAMNYEQDIGLYTIKVATDPRALNRVVIYRPSTNIITQLELISRWEKKIGKKFKKIHVPEEEIVALTKELPEPENIPIAILHCLFIDGATMSYDFKENDVEASTLYPELKFTTIDELLDIFVHDPPPPASAAF
What is the function of this protein?
Catalyzes the synthesis of the phenylpropene eugenol from coniferyl acetate (PubMed:16782809, PubMed:17912370).  Phenylpropenes are produced by plants as defense compounds with antimicrobial and antianimal properties, or as floral attractants of pollinators (PubMed:16782809).  Eugenol is a characteristic aromatic constituent of spices (PubMed:16782809).
What are the official names of this protein?
Eugenol synthase 1, ObEGS1.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
Protein: AGR2_HUMAN
Sequence: MEKIPVSAFLLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSNKPLMIIHHLDECPHSQALKKVFAENKEIQKLAEQFVLLNLVYETTDKHLSPDGQYVPRIMFVDPSLTVRADITGRYSNRLYAYEPADTALLLDNMKKALKLLKTEL
What is the function of this protein?
Required for MUC2 post-transcriptional synthesis and secretion.  May play a role in the production of mucus by intestinal cells (By similarity).  Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.  Promotes cell adhesion (PubMed:23274113).
What are the official names of this protein?
Anterior gradient protein 2 homolog, AG-2, hAG-2, HPC8, Secreted cement gland protein XAG-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the AGR family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum.
Protein: PGGHG_DICDI
Sequence: MIINSQEYLQPPQWWNERVEAGNLLSISNGEQEPTNYLMTNVGNGYVAFVIGGESIYVGGVYNGPAINLGDANNLPSHRAGIPNFQNIEISNAQFQYAGLDIENATYTRVYSIPSSPGTIVKQIFYAHQKIRNILVQEIEVDNSNIETDVTLQLSVVGINLTANVDFNILNLTNTQFTGNDYQLYNLTIKVPEVNFMTSVAVTTTTIPQSITIKSGEKKKHHYVTSFLTNIETNDYIEGSLDIYKTTFLLADQLIKSHLDEWNKIWISGIEVGGDSHLQQVVNSSLYYLFSSIRDDWSYGMSPGGLASDGYNGHSFWDTETWMLPPILLLNPKLVRDCLLQYRINNLPGAHEKALSYKSNNYTGFMFPWESAFTGIEVCPTFAPTGILEQHITADIALAIRQYYYLTGDLDWLIDFGYKALKGIAEFWASRVEYDQLNQQYSINTIIPPDEYAVGVNNSVYTNVAVKMTFEWVIEVATLINDTENIPFEHWSSIANGLVILFDEVNQWHPEYQGYNGETIKQADVVLLGFPLMYNMSKEARKNDLIYYEAVTTNSGPAMTYSMHTVAWLELESLENATKQWFRSYNNCNNSPFLVWTETPTGGAVNFATGMGGFLQGLMFGYGGVRIHQGNLDFYPQLPEGTTSLKIRSMNYIGSTFNVGWNQTTITFEMLTFNPSVYLTLLSTEYDNIILNTLDPIYLTFGSKFQIYFNNNN
What is the function of this protein?
Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins.
What are the official names of this protein?
Protein-glucosylgalactosylhydroxylysine glucosidase, Acid trehalase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 65 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB_BORBR
Sequence: MAIQSDSLSSLPDSPRIVAPQPVSPNEESIERALRPKALEEYVGQQRAREQLEIFIAAARKRGEALDHVLLFGPPGLGKTTLAHIIAHEMGVQLRQTSGPVLERPGDLAALLTNLERNDVLFIDEIHRLSPVVEEILYPALEDFQIDILIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDRFGIVSRLEFYNTDELARIVTRSASLLNADITADGAHEVARRSRGTPRIANRLLRRVRDYAQVKAHGVIDQDAAGRALAMLDVDPQGLDVMDRKLLEAIVHKFDGGPVGVDSLAAAIGEERDTIEDVIEPYLIQHGYLQRTPRGRTATLTTWRHLGLTPPAAASGGTGELFSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MINC_BAUCH
Sequence: MIHAPIDFKGSNFTLLVIHIYDAPIEVIIQAIQDKITQAPQLLKNAPVILNVASLSPECNWINLLKAILSTGLHVVAVSGCNNSTLKNDIIISGLPLITEGQTLQCSSYTTTPIKSTLSINNKTKLIHTPIRSGQQIYAKNSDLVITNNVSAGAELIADGNIHIYGMMRGRALAGASGDSHCQIFCSYLFPELVSIAGQYWIDDQIPAELLGKAGRIYLHCDALSIQPLIF
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: ASTC_SALHS
Sequence: MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMHYGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNTINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQTGGASCG
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.