PharMolix/UniProtQA huggingface dataset:
Protein: BFR2_CRYNB
Sequence: MSGLSLAQQLKQLHSNNVSVPDPESAYSNLDSHDIQRKGDEGREHYVDVGPSRLRMELGGTGGGTLTGPKYEGVKTGRMKIFDDDDDDDDDREGNGSEEGSDGEGDEDEDGDEDDEDEEDEDEDEEESDEDEQGEDEDEDEEEQPQPRANGSKQALDPVASLRNSRLKDVEKGQAIRKQKALFESLITLRITFQKALTASNTVPPTLPEDPENELAYKKASILKSLGELNERLFTLRESISLPGELGEDVSLGKRKRAEGDDAQGQAYWIKAAKESLGIADRSHPQLLPILNKWSSKIQAASLQLGSKQAGGSKFLQQMKNGAGGVVEAIESGINSKREAEKTLMESEETGYRALLREVIESRSGSGPAADLTHLRREKKKKREAERGGSKGRKLRYTVHEKAQNFVVPIPLSHGWHEEQVDELFSSLFGGVGMKGATAEKTVGLDVGTADEGLAELGGLRVF
What are the official names of this protein?
Protein BFR2.
What is the protein family that this protein belongs to?
Belongs to the AATF family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: UGO_TOXGG
Sequence: MRMQWFLLRHAYFIKGEDFAVAVALLDLALYVLIGTNSLQFLDQSPEKALFGMITSALIFIIALCGFVIVRMFRTSKYKIETYIMPVLIICNIASVFYMQLINKLVGFMTLQLPVLTFLITGYPYVWLVAFVLIGMGGGLIAQSVVCSVSLGSSCPPSVWVDVGLYALQLISGSVAYFTVYELGILIVRYKRHPARYLDAFSDLTALDTIVFSPVFGLGGETARQVQVNQLMAPEKPNLDGLTFLRSASQVSQTTNRIVSRAFYHANTPPHSSSRDALPADKALGAERSDRAGSAVFSPNTLGPLGAPSAGLRDFGPGRPVPGASVVVPKSLKQHAAALHAGANSPHGSPPLQPHGALPGAPRSNTLRGCSGQVSLVPREEESDPACGSLRASVESKATHRSAATLSACESKSRSGRVAGLFRGLSKRPGGPDCEEAAPAEPATSLGSKELGRKKTAGSKAQSSVPILLPRPQSIEETTWRGLASGDLSKDTPVASLASRRNLRMDEQSGDADKASSDVSRDPAKKGAGPFVAEAPVHTAVLPSSSFHSEFPLSRRDSGKELLSDLRESRERTARAASHDTHAAADDSGLQGDPALAAEARVRTALHYHRRWFFSQLFHFRRARRRHRRGAGARDGELVFERGEPDEVESEESCDDSRSRPRETASLSHFSRLSRSRRHKTRTYRRGRSSDGTTAGTSDSDSHGESLEDEGSDSGQESESEESRRRRMRSSRNRRRETSSEDSSSGTSVRSEGRHCREGRANSSVFSSGIRRYFSFFSAATRCAHAASSEEERPVRPARHSWRRGSGDSRECSASTSGVSEACEHSSDASWASSSSLCGSCEKRSIRMSRRRRREGKSRPHASSVSRAERHRGHVSVDLAPLLPSRLFFDTFLNSVRRAERLSKEGRLPASVSRQSSETRGSRTAFLNGDKGCSPTSEAPERSFPASANEVSFRRNEGWERYYDMLLPSLPPFPSARPLYVKPRKNSQAFQNVAVSVSRNETEMTASSPATSFDGPRAVSLSPEGRGARESSDGGGATAPSDLHSRPARAKSLVAAMLHTYPTCPQPPSDLSLFTTPPASPSSLNEVQASRSSSARITSVELGALGKQQGEAAPAGTDAVEEDRDATEDARGSLSSPTGASRRGDRCRRSWSSCEARSSVEMKPNLSIRDARASESPLQSAAPLLSEEKKSRKAQSCAQCRRCGRSRTRLQPSGRLGSSSREDLVGEADSHVSPEKEVFVSSRREKREEQVPRSRREERRDRRGRRWRRGRRRRKARECSETEERRDSSSEWSGTQYSSQERRSHEAVGGVAQLTPICVDDECGKGDAGLSPLLRSEAEESEGEGDMRERQIYETHSDGDVEELSEEEREDRGRSWLRWLFPWGAGEGQGGEKNRRKRSRSEGRREREFISAERRYLEHHRRSRVSSVADSRWGSGSEASADAYPALRRRKGSRVYPVSKPQWFQPSGLTACSSKNSWLAVPPDISLVSAAPALPTPSPSSLSFSGLDQELDCDANSSTAVSSSLPDSTAWQGSGAAASASSPSLRASVDAHFAEAELHAAEHSDGVSVSPRNSPGALSARPMSAAGMPNPDSGIATQTPQTPQTPHTQRPLLLAQSLVAASGKPLPPTRADFEAQRSQGLGDLSQKTPRVFSPQGLGRSQGYGPGGSSYALDSSREAGPSGRLSATPSTRLQGSGGPAFPHSSFPQAIGAAGTPTAPSRDSRTFFGDTGAARASRAGLSGRLASRGTALAPKGTRRLKSGYSVGAADAKDKQKGKVLRYQLVQKFHDRLPWWVARIIVYTDAALENCRRRRRLMQRATWKTKVAMPVRNMLGLFSDEKIETWYVQWLNAFNAKYYPRVAWLLFLICFYATAFHGLLRLRGFIENYPLCIDAVRASPLGEAGFLILVAVRFASQPILSFLLLLPLLRHSGSRLIDFLFCSRAPATPLKSYKLYRWMLALSFLQFVYAVFDNTWHLIAEPGSRHVNPLTIIPASPSLEIAAVQTVYILAVRTPTINLIFLLYIITYIIIFFVALPPGVQQVQLFTISMAGWLFTCVGGQLFYTRAFEVNRRRLFCKYVLPYMLYLEEIAAILYSNPQGEYPLDEGSEDEVSMGSGHLVGDRSA
What is the function of this protein?
In tachyzoites, required for the cellular trafficking of guanylate cyclase GC to the cell membrane and for GC guanylate cyclase activity.
What are the official names of this protein?
Unique GC organizer UGO.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=In intracellular tachyzoites, localizes to the apical cap, to the cytoplasm in disperse foci and to the residual body.
Protein: KDGT_ECOLC
Sequence: MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OVOS_ANAPL
Sequence: ASFSVVGDIMGTSMQNLHQLLQMPFGCGEQNM
What is the function of this protein?
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism.  This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases.  When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase.  The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced).  Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
What are the official names of this protein?
Ovostatin, Ovomacroglobulin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: EF1A_METBU
Sequence: MADKPHMNLAVIGHVDHGKSTFVGRLMFETGAVPAHLIEKYKAEAKEKGKESFAFAWVMDTLKEERERGVTIDISHKRFDTDKYYFTVVDCPGHRDFVKNMITGASQADAAVLVVAAPDGVMAQTKEHVFLSRTLGINQLIVAINKMDAAKYSEDRYNEVKKEVSQLLGMVGFKADDVPFIPTSAFEGDNITKSSANTPWYTGPALLECLNNLTVPSKPDTLPLRIPVQDAYTISGIGTVPVGRVETGIMKKGQKVTFMPSGATGEVKSIEMHHEEWDQAVPGDNIGWNVRGIGKNDVRRGDVCGPADKPPSVADEFTGQIVVLQHPSAITVGYTPVFHCHTAQTACTLMAINKKLDPKSGQVKEENPTYIKAGDAAIVTIKPTRPMCIEPVSEIPQLGRFAIRDMGMTIAAGMCMSVTQKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGX16_CENEX
Sequence: DRDSCVDKSRCAKYGYYQECQDCCKKAGHSGGTCMFFKCKCA
What is the function of this protein?
Blocks Kv11/ERG potassium channels.
What are the official names of this protein?
Potassium channel toxin gamma-KTx 1.6, CexErgTx1, CexErg1, Ergtoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ENDO4_ARATH
Sequence: MSSSLRQWFARVLVLTQLINGALCWGKEGHYTVCKIAESYFEEETVAAVKKLLPKSADGDLASVCSWPDEIKHHWQWRWTSPLHYVDTPDYRCNYEYCRDCHDTHKNQDRCVTGAIFNYTMQLMSASENSDTIVHYNLTEALMFLSHFIGDIHQPLHVGFLGDEGGNTITVRWYRRKTNLHHVWDNMIIESALKTYYNKSLPLMIEALQANLTNDWSNDVPLWESCQLNQTACPNPYASESINLACKYAYRNATPGTTLGDDYFLSRLPIVEKRLAQGGIRLAATLNRIFSSKPKHAGS
What is the function of this protein?
Endonuclease that can use single-stranded RNA and DNA as substrates (PubMed:23620482).  In contradiction with PubMed:23620482, cannot hydrolyze single-stranded DNA and does not cleave mismatches (PubMed:17651368).
What are the official names of this protein?
Endonuclease 4, AtENDO4, Deoxyribonuclease ENDO4, Single-stranded-nucleate endonuclease ENDO4.
What is the protein family that this protein belongs to?
Belongs to the nuclease type I family.
Protein: CCME_DECAR
Sequence: MKSRHKKLALIGGALAIIGIIAALVLNALNSNIALYISPTDVAEGKAPQGKAFRIGGLVKEGSLQRQADGVTIAFVVTDTAKDMTVHYKGILPDLFKEGKGVVAQGKMAADGTFTASEVLAKHDENYMPPEAAKAVGDAQAKSAGAEKPKASY
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SYH_BACFR
Sequence: MAAKPGIPKGTRDFSPVEMAKRNYIFNTIRDVYHLYGFQQIETPSMEMLSTLMGKYGEEGDKLLFKIQNSGDYFSGITDEELLSRNAAKLASKFCEKGLRYDLTVPFARYVVMHRDEITFPFKRYQIQPVWRADRPQKGRYREFYQCDADVVGSDSLLNEVELMQIVDTVFTRFGIRVCIKINNRKILTGIAEIIGEADKIVDITVAIDKLDKIGLDNVNKELAEKGISEEAIAKLQPIILLSGTNTEKLATLKTVLSDSETGLKGVEESEFILNTLQTMGLKNEIELDLTLARGLNYYTGAIFEVKALDVQIGSITGGGRYDNLTGVFGMAGVSGVGISFGADRIFDVLNQLELYPKEAVNGTQLLFINFGEKEAAFSMGILSKARAAGIRAEIFPDAAKMKKQMSYANVKNIPFVAIVGENEMNEGKAMLKNMESGEQQLVTAEELIGALTK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_MYCUA
Sequence: MTNDPGSGFAAVWNAVVAELNGEPNTDGDAGTGTTLTSPLTPQQRAWLNLVQPLTIVEGFALLSVPSSFVQNEIERHLRTPITAALSRRLGQQIQLGVRIAPPPADDDDDSVAAAVEDPGLEASPETSQEVSDEIDDFGENAPKSRQSWPTHFKKRSTDADTSASADGTSLNRRYTFDTFVIGASNRFAHAATLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIEGKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPELETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALIRVTAFASLNKTPIDKALAEIVLRDLIADADTMQISAATIMAATVEYFDTTVEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQRKILSEMAERREVFDHVKELTTRIRQRSKR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLBF_ECOLI
Sequence: MTIIHPLLASSSAPNYRQSWRLAGVWRRAINLMTESGELLTLHRQGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPPAHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLGKGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQGYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP
What are the official names of this protein?
Uncharacterized protein YlbF.
Protein: HRCA_STRP6
Sequence: MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFKLEDMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: GLK_EDWI9
Sequence: MSRFALVGDVGGTNARLALCCLDTGSLEAVQSYPGQQFDSLESVIRTYLQAQAVSVTSACIAIACPITGDRVAMTNHSWAFSISAMQRSLGLAHLSVINDFTAVSMAVPVLPAESLLQLGGQTVQPDRPIAIYGAGTGLGVAHLIRAGERWISLPGEGGHVDFATGSDEEDALLAALRTDLGRVSAERVLSGPGLVNLYRAVARVAGRTPQPLTPQEVSERALADHCPDCRRALSLFCVMMGRFGGNLALNMGTFGGVYIAGGIVPRFLAFFRDSGFRQAFEDKGRFKAYLAPIPVFLIVHDNPGLLGAGAYLRQHLGARL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_HALS3
Sequence: MRVVVSIGGSVLAPGLDADQVDAHADAINELTDAGCEVGAVVGGGGVARDYIGTARELGANEIELDDIGVDVTRLNARLLIAALGGDAAPSPAEDYEDAGEAMRRGDIAVMGGVVAGQTTDAVSAALAEYTDADLLLYATSVPGVFSADPNEDADAEHFTRMTAGELVDIIADIEMNAGSSAPVDLLAAKLIERSGVRTIVLDGTDPRRIVDAVRFGEHDGTDVIPDGTDNQMTYWADNQE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AI5L3_ARATH
Sequence: MGSIRGNIEEPISQSLTRQNSLYSLKLHEVQTHLGSSGKPLGSMNLDELLKTVLPPAEEGLVRQGSLTLPRDLSKKTVDEVWRDIQQDKNGNGTSTTTTHKQPTLGEITLEDLLLRAGVVTETVVPQENVVNIASNGQWVEYHHQPQQQQGFMTYPVCEMQDMVMMGGLSDTPQAPGRKRVAGEIVEKTVERRQKRMIKNRESAARSRARKQAYTHELEIKVSRLEEENEKLRRLKEVEKILPSEPPPDPKWKLRRTNSASL
What is the function of this protein?
Binds to the embryo specification element and the ABA-responsive element (ABRE) of the Dc3 gene promoter and to the ABRE of the Em1 gene promoter.  Could participate in abscisic acid-regulated gene expression during seed development.
What are the official names of this protein?
ABSCISIC ACID-INSENSITIVE 5-like protein 3, Dc3 promoter-binding factor 4, AtDPBF4, Protein ENHANCED EM LEVEL, bZIP transcription factor 12, AtbZIP12.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. ABI5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVB_ACIAD
Sequence: MHDRLISGTEKPEDHFDRAIRPTSLADYIGQPVVREQMEIFIGAARGRGEALDHTLIFGPPGLGKTTLANIIAREMGGNLKSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVAATTRAGLLTSPLRDRFGIVQRLEFYSVEDLTHIVTRSANLMNVPMTSTGAAEVARRSRGTPRIANRLLRRVRDYAQVKGTGEVTHDMAQRALDMLNVDKDGLDTLDRRYLSMLLERFDGGPAGVEALAAAMAEDSGTLEDVIEPYLIQQGYVMRTARGRIATNMAYLQFGLTPPEPKN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: REPA_BEYDV
Sequence: MPSASKNFRLQSKYVFLTYPKCSSQRDDLFQFLWEKLTPFLIFFLGVASELHQDGTTHYHALIQLDKKPCIRDPSFFDFEGNHPNIQPARNSKQVLDYISKDGDIKTRGDFRDHKVSPRKSDARWRTIIQTATSKEEYLDMIKEEFPHEWATKLQWLEYSANKLFPPQPEQYVSPFTESDLRCHEDLHNWRETHLYHVSIDAYTFIHPVSYDQAQSDLEWMADLTRMREGLGSDTPASTSADQLVPERPPGLEVSGDTTTGTGPSTSPTTMNTPPIISSTTSPSSSSHCGSN
What is the function of this protein?
Implicated in enhancement of V-sense gene expression.  Acts a an inhibitor of C-sense gene transcription.
What are the official names of this protein?
Replication-associated protein A, RepA.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=distributed equally throughout both the nucleus and the cytoplasm.
Protein: FAP1H_SCHPO
Sequence: METSKNPSDLPKKPANVKKNRRRFQKSQKKSISPSSGSELPNFKTTISQNNEEVKTSLKEDSSKFHPSASAPIFVPTSSVQLNVSKNNGHKASDIVDAVSSKDEELRKHAKGEGKRSKNRKRSSKHSEKQAVDLKSSNSSQETSSSKGSVNNKSERSREAKSRMPKNSKEIKKGLDLSKLDMTSRMIVELKNRLYECSVCTDTINPSTSIWSCGTCYHVFHLSCIRKWCKNSIEQRNEDAWRCPYCQSNQTETSLHYLCWCGKQEKPEFVKNLVPHSCGDPCGKTRGQDCEHPCPLLCHPGPCPPCTATVEKFCLCGKESIHARCSNISKVNTEPFRCENVCDELLPCGEHTCKKRCHSGLCGACFEPINAKCYCGLHSKTYPCSSLPSPSISKKDENGSVKEWFGYYSCNNPCTLFFDCGLHKCSKTCHPISETRAHCPFATDVLTKCPCGKEDISFLLKGHERKSCSDPIPTCENICGKLLSCGHRCKYKCHLGSCGTCSETLTIPCRCTANEVQVTCEQLQNGFIPTCERLCTILLSCGRHQCNKKCCSGYSKAQTRLARRPKGAKLRYHLLTEEFEEEHICFRPCNKKLSCGNHFCQHMCHRGPCPRCLEASFEELPCTCGRTRLYPPVACGTPIPDCPYLCVLPKSCHHPQVKHNCHPTSEPCPPCPYFVKKRCLCGKHILENQPCYRENVRCGELCNKLLSCKTHFCEKLCHPDGECESSCKKECGKRRMYCEHVCQSPCHAGHPCDERIPCKAPLEVSCECGRIRKKVTCDASYDNPDPQHKVSCTLECSQQQRNKLFAEALNIKTDRRSNDVAQYTKSLLVFYGKHSDFADEVESLLRNFVNNKASSFRFPSMRREQRAFVHMFAKLLGLESVSFDPEPKRNVMVYNKGEAKLPNMLLKEANLYHLQHPEIPLKPDSLLGPEEENATASHIDGSSNASDSGYNAFVLKELLKEVNDESAIFSVLDDIVDFNHLTWSILFGENYIILKPLNTDLIVNKTGKLVALRPLVNRRLADAGIASRCEICEINDKNEIVKTRSQRIHSKKKAFLSLVPDKSIGVINRYKELATEL
What is the function of this protein?
May play a role in transcription regulation.
What are the official names of this protein?
FKBP12-associated protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the NFX1 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Nucleus.
Protein: TFB1M_DROPS
Sequence: MSQVTARVLNSGMRLPPLPTIRELVKLYKLQAMKQLSQNFLMDERLTDKIVKSAGRIDPRDIVLEVGPGPGGITRSILRRQPQRLILVEKDRRFGETLQLLRECASPLDMQVDIYYDDILRFNIEQHIPDTTQRIHLIGNLPFSISTRLLINWYADLAARRGAFRRNDTCMTLTFQKEVAERICAPVGSEQRCRLSVMSQIWTEPVMKFIIPGKAFVPKPQVDVGVVKLIPLKQPKTQLPFSLVERVVRHIFSMRQKYCRRGYGTLLPPDSREETTQTLFQRADVRDTLRSFELSVPQCLRLADAYAEYIKEHPEVEAYDYRGPKNPDVSGAAAASS
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop.
What are the official names of this protein?
Dimethyladenosine transferase 1, mitochondrial, Mitochondrial 12S rRNA dimethylase 1, Mitochondrial transcription factor B1, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YIDD_RUEST
Sequence: MRLLARLIALPVRGYRLLFSPWVGFNCRYQPTCSAYALDALERHGPFKGTYLMLRRIGRCHPFGGSGYDPVPGADPKHDRCCGRTP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OR2C3_HUMAN
Sequence: MMEIANVSSPEVFVLLGFSTRPSLETVLFIVVLSFYMVSILGNGIIILVSHTDVHLHTPMYFFLANLPFLDMSFTTSIVPQLLANLWGPQKTISYGGCVVQFYISHWLGATECVLLATMSYDRYAAICRPLHYTVIMHPQLCLGLALASWLGGLTTSMVGSTLTMLLPLCGNNCIDHFFCEMPLIMQLACVDTSLNEMEMYLASFVFVVLPLGLILVSYGHIARAVLKIRSAEGRRKAFNTCSSHVAVVSLFYGSIIFMYLQPAKSTSHEQGKFIALFYTVVTPALNPLIYTLRNTEVKSALRHMVLENCCGSAGKLAQI
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2C3, Olfactory receptor 2C4, Olfactory receptor 2C5, Olfactory receptor OR1-30.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF12_CUPMC
Sequence: MAKDDVIQMQGEVLENLPNATFRVKLENGHIVLGHISGKMRMNYIRILPGDKVTVELTPYDLSRARIVFRTK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_MANSM
Sequence: MHKLRKIIHIDMDCFYAAVEMRENPALRDKPIAVGGSVQQRGVLTTCNYPARKFGLHSAMPTGQALKLCPDLILLPVNITLYKQVSHQIKQIFHRYTDNIEPLSLDEAYLDVTDCVQCSGSATWIAEEIRRAIFNELHLTASAGVAPLKFLAKIASDQNKPNGIFVITPGEVDNFVKTLPLSKIPGVGKVTGQKLLQMGLKTCGDVQKLDLTVLLNRFGKFGQRIWQYSHGIDEREVQSHWQRKSVGVEDTLLRNITDIEQGIVELERLYPILEQRIKRACPDIPFERFRKLGVKLKFEDFQVTTLEKSAVEFKRENFIVLLRQIWQRRQGRAIRLVGLQVTIPEQKAEQQMSLW
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMGA_STRCA
Sequence: LPVTNNMNKGDTKVMKCIVEVISDTLSKPNPLPISEECLETLRGDERIISILRHQNLLKELQEIAVQGANERTQQQRRTEDQELESLAAIEAELESVAHSLQAL
What is the function of this protein?
Chromogranin A probably has a paracrine role in the regulation of secretion or maturation.
What are the official names of this protein?
Chromogranin-A.
What is the protein family that this protein belongs to?
Belongs to the chromogranin/secretogranin protein family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted.
Protein: SECA_LIMF3
Sequence: MANILRKWIESDRRELRRINRLANRVDSYQDQMAKLTDDELKAKTPEFRQRIQDGEDLDHLLPEAFAVAREGAKRVLGLFPFHVQVMGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALSGKGVHVITVNEYLSERDAEEMGQLYRWLGCSVGVNGAQKSPDEKRAAYACDIMYSTNSEIGFDYLRDNMAVYKEDQVQRGLNFAIVDEVDSILIDEARTPLIISGPGTGTSKLYQQADRFVKTLKNEDDYKIDLESKTVSLTDEGIKKAEKYFNLKNLYDPENTALTHHLDQSLRANYIMLLDKDYVVNDGEVLIVDSFTGRVMEGRRFSDGLHQAIEAKEGVEIQEENKTMANITYQNLFRMYSKLAGMTGTARTEMEEFREIYNMETITIPTNRPVARVDEPDLLYPTLESKFRAVVKRIQALHEKGQPVLVGTVAVETSEYLSHLLDQQKIPHVVLNAKNHAREAEIIKNAGQVGAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGLSQFYLSLEDELMKRFGGDRIKNFLQRLQTDDDDEDVVIKSRFLTHQVESAQKRVEGNNYDSRKNVLQYDDVMREQREIIYRERQQVITEIDSLKWVLMPMVKRTIQRAIDAHTLGDKKDWKLQEIVDFAVEVLVKPDQITVGMLEGKSKDEMVDLMMDFAEQVYEEKKHQLYDDSQMLEFEKVVILRVVDAHWTDHIDAMDQFRQSVGLRGYGQQNPLVEYQTTGYRMFEQMVADIEYETTRLFMKSEIRQNVTR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: ISPG_PSYCK
Sequence: MSTSAPINRRLTKKIYVGDVAIGGDAPISVQSMTNTDTCDVAATVAQIERCVEAGADLMRVSTPTMDTVKAFGEIRKLVSVPLIADVHFDHKIALAVAAAGADCLRINPGNIGSDAKVREVVACAKHYNIPIRIGVNAGSLEKDIQRKYKEPNGAAMLESAMRHIDILERLNFDQYKVSVKASNVFLTMDAYRLISAQIDNPLHLGVTEAGVYRTGSVKSAIALGGLLLDGIGDTIRISLAAEPEEEIKIGFDILKSLNIRSNGVNFIACPSCSRQEFDVIRVMTALESRLEDIREPMNLSVIGCKVNGPGEAKEADIGIVGAAPKSLVYRMGEKSHLIDTDNLVDEIEGMVRAHAEELAKKRENEIIRVR
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.