PharMolix/UniProtQA huggingface dataset:
Protein: SYL_STRA3
Sequence: MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKAAAIAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQVLTASGQSISYVPWPSYDESKLVENEIEIVVQIKGKVKAKLVVAKDLSREELQDLALANEKVQAEIAGKDIIKVIAVPNKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABG_RICTY
Sequence: MIDFTGKTSLITGASGGIGSAIARLLHKLGSKVIISGSNEKKLKLLGNTLKDNYIIEVCNLANKEECNNLISKISNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPGFIKSDMTDKLNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNHASYITGQTLHVNGGMLMV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase FabG, 3-ketoacyl-acyl carrier protein reductase, Beta-Ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PSTB_DESPS
Sequence: MPAGLITALPNQLRAITMQLRLDTNGELSETSQQTVGVPFVENARMTCRKVDVHYGEKCAIKNISIDVGRNEVLAMIGPSGCGKSTFLRCLNRMNDSLASCRVSGDITLDGVNIYAPTVDVVPLRAQVGMVFQKPNPFPKSIFDNVSYGPRIHGLATGKADLSEIVESSLIKAGLWDEVKDRLHESGTSLSGGQQQRLCIARAIAVSPEVILMDEPCSALDPIATAKVEELIAELSTQYSIVIVTHAMQQASRVSQRTAYFHMGSLVEVGATEKIFTNPGHQLTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DUT_RHOPA
Sequence: MTQKITVSIRHLPHGEGLPLPEYQTAHAAGLDLIAAVPQDAPLTLQPGRYVLVPTGLTIALPENYEAQVRPRSGLAAKHGVTVLNAPGTIDADYRGEIGVLLINHGTEPFAIRRGERIAQMVIAPVSRAQFVAVEALPESGRGAGGFGSTGR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: SYI_DESAP
Sequence: MDYSKTLNLPTTEFPMRANLPQREPEIGRFWDEIEVYQLVQAKNAGRPKFILHDGPPYANGHIHLGTSLNKILKDIVVKFKSMDGYNAPYVPGWDTHGLPIEQQAIKQLKIKRSALSPVEFRRMCREYALKFVDIQRAEFKRLGVRGEWHNPYLTLQPHFETRQIEVFGEMAKRGYIYKGLKSVYWCADCETALAEAEVEYAEKESPSIHVAFPVVNGRGLLPDQDAAIVIWTTTPWTIPSNVAICVHPEYAYVLLRSGGRAYLVARDLAGNFRELLGDPGAGVEREYRGEELEGVVCRHPFVERDSVVVLADYVTLEQGTGCVHIAPGHGEEDFALGQRYNLPVISPINGKGYFTAEAGNLDGIFYLDANPVVVRELEARGALVGYSRMRHQYPHCWRCKHPVFYRATEQWFASIDGFRRHLLEAIDRVQWIPGWGRDRIRGMVAGRGDWCISRQRVWGVPIPIFYCGDCGRAVITDETISHLKGLFAEHGSDVWYAWEAAELVPPGLVCPHCRGRGDFTKELDTMDVWFDSGSSHWAVLTQPDYWPDLQWPADMYLEGSDQHRGWFNSSLTTAVAVTGEPPYRAVLTHGFVVDEQGRKMSKSLGNVIEPMEVLKELGADILRLWVCSADYRGDLAVSPGILKQMSEAYRKIRNTFRFLLGNLQDFDPDRDTVAYTELTELDRYALLKLHRVTDRVLRAYREYEFHQVYHTLYNYCVTDLSAFYLNVIKDRLYCEPARSVNRRGAQTVLYAVLDSLVRLLVPVLAYTTEEVWGHFPANGKKPPSVQLLEMPEPNPEYLDDELERRWERLLAVRQDVLRALEAARQEKLIRDALEAEAVLYAEPELLEFLRENTVQLPVIFVTSSVRVLPAAEAGGEEAVSGTVAGLKVAVRRAPGTKCVRCWTYGETGVDPEHPEICPRCATVLSGLNL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_CLONN
Sequence: MKKNERIRKNIEFRRVYRRGKSYSNSLLVLYVFKNNNNVDTSRVGISVSKKVGNSVVRSRVKRLISESYRLNCSNIKEKYDLVFVARNKSKDKTYKEIEGSVTNLLKRAGLYN
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CH60_STRPM
Sequence: MNMAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEGLKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFILITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGSGSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKLRIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQIALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVASLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_ECO7I
Sequence: MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDZ1_CAEBR
Sequence: MQFSIVYFLVFLIPSTQSTGFLSLKLTSDHDCLVHLEIQSMEYSETVRLLAYETKSLEIFTPEITNQLSIHFQILHHFSGVSLSDVSSQLFKLDNNGIWEPRVIDSDQVILSIQSNFHCQKGFYGPICERRSRSTSTIKTTTSIPTATSSPFHLPISEVQINNLIIYAVLSSVVLLLIIANCFLCFCRPKPSKYIDYTFQNVFPMDEFFPMEKTIGSPDTEYFDSSSRYYSTITLQSRV
What is the function of this protein?
May have a role in mesendoderm development during embryogenesis.
What are the official names of this protein?
Skn-1 dependent zygotic transcript 1 protein.
Protein: AHPD_MARMM
Sequence: MSIDALKNELPEYAKDLKLNLSSLGRETELDDQKKWGTFLASAHAVGEPKTLAAIKAEAETRLSDEALTAAKAASAIMGMNNVYYRFVHLSKNKEYATLPAKLRMNILANPGVDKADFELWSLAVSAINGCGLCIDSHEAELRKHGLTTTQVQAAVRIAATVNAIAAVLAAES
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: DCYD_ECO27
Sequence: MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTPMAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNTQLEELATRVEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGVTVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLARLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: HIS4_PERMH
Sequence: MGLRSFVIPAVDIKDGKAVRLYKGDPEAVTVYGDDPVSVAKQWEEKGAKHLHIVDLDGAFEGKPKNIDIVKDIVKTVSIPVEFGGGLRSFEAVKSIVETGVERVVIGSLAYQNRQEFERIVSAYPGKVIVGIDAKDGKVAIKGWLEKTEYTPLDFARMFDDLDIWGFLYTDVNRDGAMVGPNIEGTKYLAQNLKHPVIASGGVGSVEDLKKLYDLKKYGVYGVVVGKALYEGKIKLEQLED
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_METPB
Sequence: MTLIGWFQIALFCAVVLALVKPLGAYMTRVFAGERTILSPLLAPIERGLYRAAGIDARHEQTWLGYGLAMLVFHALGFVSLYAILRLQDGLPLNPMGQAAVAPDLALNTAVSFVTNTNWQNYGGESTLSYLSQMLGLTPQNFLSAATGLALAVALTRGFARASSRTVGSFWVDLTRCTLYVLLPLCIGLTLFYVWQGMPQTLGASVDATTLEGARQTIAVGPVASQVAIKMLGTNGGGFFNANAAHPFENPTALANLVQMVTIFALGAAMTNVFGRMVGDERQGWAILAAMGVLFLAGVAVTYASEAAGSPVLNGLGFSAGNMEGKEIRFGIVASALFAVVTTAASCGAVNAMHDSFTALGGLIPMLNMQLGEIIVGGVGAGLYGMLVFVLVALFVAGLMVGRTPEYLGKKIEAKEVKMAMLAILCLPLMMLGLAALATVLPAGLAGPANAGPHGFSEILYAFTSAAANNGSAFGGLTGNTLFYNTTLALGMAVGRFMVIVPALAIAGSLAAKKTLPASAGTLPTHGGLFVGLLVGVILIVGGLTFFPALALGPVVEHLAGAAGQTFAAGG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LYSZ_SULIM
Sequence: MIVVKIGGRVVKNSLDKVILDIANINDKVILVHGGGDIVTDYTKRLGIEPVFVTSPEGIRSRYTTKEELEVYIMAMSLINKTITSKLCSLGKNAIGITGVDGGLLLAERKKRIIVIDERGKKRIIEGGYTGKVKEVRSEVINHLMKLFDIIVVSPLALDVEESTPLNIDGDQAAFAISKAVKVNVLVILSDVEGVLVEGKVVDRLTPEEAKELSKKIGPGMNRKLLMAAESVENGVNKVIIGSGVKDRPVSSALELNGTVIVNG
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.  Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
What are the official names of this protein?
[LysW]-aminoadipate/[LysW]-glutamate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. LysZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDR4_TRIT1
Sequence: MAVEEKNSPTGAAMTNTGILVPSSQQSLPEWWTKTQKFFSRENTITPTFGYFRLLFGTQPGKTDIALIVIGTIAGIGAGIPFPLLGILFGELVDDLNSSTCSTTQAPPGGYQAAITTKVLQVIYVSILNFVCMYIHTGCWSMVGERLVRRLRTKYFHSLLRQEIAFTDTLPSGDVTSRLVSDIEVIQAGTSEKVGLFIGTISYFVAAYIVAFLKVATIAAMLMSVVPIYFLMAFGGGHYIKKYSGRISTHINAATSIVSSSLSHMSIVHAFNANARLEALFAQHLVSARMDALKKAITHSIQFGMLYFVAYASNALAFWQGSRMIADLAEGKPSKVSVGAVYTVIFVLLDASFVLSQMAPFMHIFASAASAGDRLMTTIKRQSAIDGTSSEGDSTISLASEEIELQDVTFNYPARPEVPVLQGVSFKIPPNKHTAIVGTSGSGKSTVVALLERLYDPITGCVRVGNRDLKEINVRHLRGSIGLVQQEPNLLDRSILENIAHGLVSSSQEKHKHLLPTLLGPSLSELTEKIRQGASEDEAVTEQGDVVREIVNLTRHAATLSNAIDFINALPDGLATRVGSSGAELSGGQKQRIALARALIRDPPVLLLDEATAALDSTSERLIQAALNKVSENVTTVSIAHRLATAKDADNIIVMQKGRVMEQGTHMDLVARDGVYAGMVRLQNIGKFSSSSSIMTESTQVDANIDRSLTTDTLLNKEEKLSLEQGVLDEKEKPAQLYMPEEADSLPTEPENEKEKPKQTLWATMKGSFPLIRPNILLISLGLITSIMIGVSYTGEAVIFGHTVGSLSVCRGGPSIRSSGMLFGLLFFILAIVKFAAVIVNGAAFGWAAEKTLYRTRVLSLRSLLRQPLEWHNADGRTPGLLVALVTSDASALSSLTGTTIGVLFSTVANLFAGVILSQCHRMEDSRSPSGYLTRIKHQKAYAKATAITVESVDNIKSIAAFSLEQEAYSVFNRSLKAPYKSNMKSVLHGNFWLSLAYSISTLVYALAYWWGSQQILAGMYTQVQFFIVLPALLFSTQSCGQMFALVPDISKARIAASNIVDLLSIKHEGDEEYDKTGSKASAKHTDPRFNMLEDKPRDVEAQLITTTPSSFPTKGMGVQFRNVHFRYPSRPNQPALDDLSINISPGQFCALVGPSGSGKSTTFALLEKFYNPASGSIIIDGVDITKQSGAAFRDTIALVPQENVMFEGTVAFNIGLGARPDVEATQEEIEEACRLANIHDTIAALPDGYNTVCSQDGKQFSGGQRQRLSIARALVRKPRLLLLDESTSALDVESEKHVQDALAKVARKTTIVAIAHRLNTIHRADRIFMIERGRCVDQGTHAELVERCESYRANVIHQSLDA
What is the function of this protein?
Pleiotropic ABC efflux transporter that may be involved in the modulation susceptibility to a wide range of unrelated cytotoxic compounds.
What are the official names of this protein?
ABC multidrug transporter MDR2, Multidrug resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUC_ECOSE
Sequence: MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PA2B6_CRODO
Sequence: HLLQFNKMIKFETRRNAIPPYAFYGCYCGWGGRGRPKDATDRCCFVHDCCYGKLAKCNTKWDFYRYSLKSGYITCGKGTWCEEQICECDRVAAECLRRSLSTYRYGYMIYPDSRCRGPSETC
What is the function of this protein?
Monomer CB: The basic subunit of crotoxin is a snake venom phospholipase A2 (PLA2) that exhibits weak neurotoxicity (PubMed:17203389, PubMed:16003952) and strong anticoagulant effects by binding to factor Xa (F10) and inhibiting the prothrombinase activity (By similarity).  In addition, it exerts myotoxicity (PubMed:17203389, PubMed:16003952, PubMed:17915277), nephrotoxicity, and cardiovascular toxicity as well as anti-inflammatory, immunomodulatory, anti-tumor and analgesic effects (By similarity).  Also shows a strong antimicrobial activity against X. axonopodis passiforae (Gram-negative) which is completely dependent on the enzymatic activity (PubMed:16003952).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 crotoxin basic chain, CB, Crotoxin-B, svPLA2, CdcolF6a, F6a, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EXPB8_ORYSJ
Sequence: MVSGDVGVVVYYLLLVLVVVQGCKGSSAVQGEGRWYNESEAIGGAAAWGNAKATWYGQPNGAGAADNGGACGFKKVNQYPFMGMTSCGNQPLYKGGKGCGSCYRVRCNRNPACSGNAQTVAITDMNYFPLSQYHFDLSGIAFGRLAKPGRADDLRRAGIIDVQFARVPCEFPGLKVGFHVEEGSSPVYLAVLVEYENGDGDVAQVDLKEAGAGGGRWTPMRESWGSVWRLDSNHRLRAPFSIRIRSDSGKTLVAPDVIPLNWTPNTFYRSFVQYSS
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found.  May be required for rapid internodal elongation in deepwater rice during submergence (By similarity).
What are the official names of this protein?
Expansin-B8, Beta-expansin-8, OsEXPB8, OsaEXPb1.11.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: ARLY_SALPC
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTADEQRQLEEALNVLLEEVRANPQQILQSDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKETVRELLTANRQLQSALVETAQANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDTLKRLDVSPLGCGALAGTAYEIDREQLAGWLGFTSATRNSLDSVSDRDHVLELLSDAAIGMVHLSRFAEDLIFFNSGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQDAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEALPLADLQKFSRVIGDDVYPILSLQSCLDKRAAKGGVSPQQVAQAINDAKARLAL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_STAA8
Sequence: MTKETQSFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSAACDTTLKNAEKKVNDLIKEEAEDVKNDESTDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_SHIBS
Sequence: MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAGAFYHRLTQCKNVRQPVNIVSHFARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSPLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYVD
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: GATD1_DANRE
Sequence: MPLGLKPCCAVCKTQSSSMWKKGNQGEILCNGCTGKAVSSGGSGASASSTIQQNNGGGKQSKQEIHRRSARLRSTKYKAPASEKKVSTKGKGRRHIFKLKNPIKAPESVSTIITSESMFYKGIYYQIGDVIKVIDEDDGKPYYAQIRGFVQDQYCEKSAALTWLIPTQASPRDRFDPSTYIVGPEEDLPRKMEYLEFVCHAPSEYFKSRSCPFPTLPVRPEKGYVWTHIGPTPAVAIKETVG
What is the function of this protein?
Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3).
What are the official names of this protein?
GATA zinc finger domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: IRC9_YEAST
Sequence: MTMQKASKVNMEVRTTLVTMQATTMSIILALPLVVLIASTLVLSVKGRRIHLATSPIILLLLILFKKGQQARSINFTLSKNKSLFCLTFLNYPFHFITAWCHNDILNKYEFCLFLIFLIRIVITINKVTL
What are the official names of this protein?
Uncharacterized protein IRC9, Increased recombination centers protein 9.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPH_YERPG
Sequence: MQILLANPRGFCAGVDRAISIVERAIEMYGAPIYVRHEVVHNRYVVESLCERGAIFIEEISEVPDGSILIFSAHGVSQAVRAEARSRNLTMLFDATCPLVTKVHMEVARASRKGKEAILIGHAGHPEVEGTMGQYSNPNGGMYLVESPDDVWQLNVKDENNLCFMTQTTLSVDDTSAVIDALNTRFPKIVGPRKDDICYATTNRQEAVRNLANDADIVLVVGSKNSSNSNRLAELVQRMGKPAYLIDSAADIQEFWLQGAKCIGVTAGASAPDILVQQVIARLKDLGAGESIELSGREENIVFEVPKELRVEVKQID
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: IKBL_ASFWA
Sequence: MEHMFPENQIENLFVGWIKKHIRNGNLTLFEEFFKTDPWIVNRCDKNGSSVFMWICIYGRIDFLKFLFKQESYPGEIINPHRRDKDGNSALHYLAEKKNHLILEEVLGYFGKNGTRICLPNFNGITPVMKAAMRGRSLNMLSLIKFGADPTQKDYHRGFTAWDWAVFTGNMELVKSLNHDYQKPLYMHFPLYKLDVFHRWFKKKPKIIITGCKNNVYEKLPEQNPNFLCVKKLNKYGK
What is the function of this protein?
IkB-like protein that inhibits the binding of NF-kappa-B to DNA, thereby downregulating pro-inflammatory cytokine production (By similarity).  Forms a heterodimer with the NF-kappa-B subunit RELA/p65 and prevents the activation of the NF-kappa-B transcription factor (By similarity).  Inhibits calcineurin function, which is required for the induction of nuclear factor of activated T cells (NFAT)-dependent immune response genes.  Prevents the binding of substrates to calcineurin without affecting the phosphatase activity (By similarity).  Does not contain the serine residues that are phosphorylated by host IkB kinase and thus is not degraded following stimulation of the NFkB pathway (By similarity).
What are the official names of this protein?
IkB-like protein, Ankyrin repeat domain-containing protein A238L, p28.
What is the protein family that this protein belongs to?
Belongs to the asfivirus A238L family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Binding to host PPP3CA/Calcineurin may mask the second nuclear localization signal thereby contributing to the cytoplasmic retention of A238L.
Protein: RS14_ONYPE
Sequence: MAKKSKIVKDQKQRELVLKYAKLRLELKKKADYAGLSQIPAKASPVRLKNRDSIDGRPRGYIRKFGISRINFRQLAHQGKLPGVRKTSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ACKA_HAEDU
Sequence: MSQNLILILNCGSSSLKFAILDPINGDEKLSGLAESFYLDDARIKWKFNGEKGNADLDAGAAHTEALNFIVSNILTDELKQSIGAIGHRIVHGGEKFTSSVVITDEVVKGIEEVIQFAPLHNPAHLIGIQEAFRIFPELKDRNVAVFDTAFHTTMPEQAYLYALPYSLYKDHGVRRYGAHGTSHYFVSREAARRLNVAEDKVNVITCHLGNGGSVSAIRHGECIDTSMGLTPLEGLVMGTRSGDIDPAIIFYMHDTLGMSVEEINNTLTKKSGLLGLTEVTSDCRYAEDNYETDDAARRAMEVYCYRLAKYIGSYMAVIGERLDAIVFTGGIGENSAHVREITLNHLKLFGYQVDDARNLAARFGNEGVITAEGSPLAMVIATNEELVIAQDTARLTITK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.