PharMolix/UniProtQA huggingface dataset:
Protein: CCR4_CANLF
Sequence: MNPTDIADTTLDESIYNNYYLYENIPKPCTKEGIKAFGELFLPPLYSLVFLFGLLGNSVVVVVLFKYKRLKSMTDVYLLNLAISDLLFVLSLPFWGYYAADQWVFGLGLCKIISWMYLVGFYSGIFFIMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVLASLPGLLFSTCYTERNHTYCKTKYSRNSTRWKVLSSLEINILGLVIPLGTMLFCYSMIIRTLQHCKNEKKSKAVRMVFAVVALFLGFWAPYNVVLFLETLVELEVLQDCTFERHLDYAIQATETLAFVHCCLNPVIYFFLGEKFRKYLVQLFKTCRGPFMLCQYCRLLQMYSPDTPSSSYTQSTGDHDLHDAL
What is the function of this protein?
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC.  The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system.  Could play a role in lipopolysaccharide (LPS)-induced endotoxic shock.  In the CNS, could mediate hippocampal-neuron survival (By similarity).
What are the official names of this protein?
C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CCR4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL2_STRR6
Sequence: MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRNNNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKAYIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGASAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NFIL3_RAT
Sequence: MQLRKMQAIKKEPASLDPTGSSDKMLLLNSALAEVAEDLASGEDLLLNEGSMGKNKSSACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISSTVYAQEIQKLSNSTAVYFQDYQTSKAAVSSYVDEHEPAMVAGSCISVIKHSPQSSLSDVSEVSSVEHTQESPAQGGCRSPENKFPVIKQEPVELESFARESREERGAYSASIYQSYMGSSFSTYSHSPPLLQVHGSTSNSPRTSEADEGVVGKSSDGEDEQQVPKGPIHSPVELQRVHATVVKVPEVNPSALPHKLRIKAKAMQVKVEALDSEFEGMQKLSSPADALAKRHFDLEKHGASGTAHSSLPPFSVQVTNIQDWSLRSEHWHHKELGGKTQGTFKTGVVEVKDSGYKVSEAENLYLKQGVANLSAEVVSLKRFIATQPISASDSR
What is the function of this protein?
Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters.  Represses transcription from promoters with activating transcription factor (ATF) sites.  Represses promoter activity in osteoblasts.  Represses transcriptional activity of PER1.  Represses transcriptional activity of PER2 via the B-site on the promoter.  Activates transcription from the interleukin-3 promoter in T-cells.  Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF).  Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock.  Protects pro-B cells from programmed cell death (By similarity).  Represses the transcription of CYP2A5 (By similarity).  Positively regulates the expression and activity of CES2 by antagonizing the repressive action of NR1D1 on CES2 (By similarity).  Required for the development of natural killer cell precursors (By similarity).
What are the official names of this protein?
Nuclear factor interleukin-3-regulated protein, E4 promoter-binding protein 4.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. NFIL3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROE_CLOB6
Sequence: MYTTGLIGKNINYSESPEIHNNYYKKNNIPFFYKIFNLKQDQIDDFIKNLHKNNIKGFNVTIPYKETILQYLNDIVYPADKIGAVNTVAVQEDKLIGYNTDYIGFIKSLQYYNIQVKNFKCLIIGSGGSAKCIYYALKELNARDICIVSRNPEKARLKFEKKVKILNIKDENKLDRYDLIVNCTPIGGPNFKEQKPIELKEIKKNCVVYDLNYTPKRSKLLKEAKENGAFIINGEKMLIFQAYSAIGLWCLNGIKGGR
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CBIC_METTH
Sequence: MMGASTGQGYEIARKSREIVRELISEDISSLGPAEVAIVERIVHSTADPEYARITEFSQGFVDEALRSLRSSGGILTDIEMVRAGISHPSRCYIREPAVRELAEKRDITRAAASMEYAASQGFRGIVVIGNAPTALMKVIELTLEGLMDARAVIGVPVGFVGAAESKEALRGTEIPHMITRGPKGGTPVAVAAANALIALSKDKEV
What is the function of this protein?
Catalyzes the conversion of cobalt-precorrin-8 to cobyrinate.
What are the official names of this protein?
Cobalt-precorrin-8 methylmutase, Cobalt-precorrin isomerase.
What is the protein family that this protein belongs to?
Belongs to the CobH/CbiC family.
Protein: PROA_STRZJ
Sequence: MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEILAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLENGLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTALKKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPVIETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASFLPRLEQVLVAERKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVAHIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQKLHARGPMGLKELTSYKYVVAGDGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNGR_ECOLI
Sequence: MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIFEVIPADDFLQQQLQITPQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENSKYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEYSRNAFNTDDYKFTLIAQRKSSR
What is the function of this protein?
Represses mngA and mngB.  Regulates its own expression.
What are the official names of this protein?
Mannosyl-D-glycerate transport/metabolism system repressor MngR, Fatty acyl-responsive regulator, Protein P30.
Protein: YQGF_ANAMM
Sequence: MLCDSIESFFGALGADRRILGLDFGEKKFGLAVSDSTGTIAMPHSVYLRRNVRQDLGELNAILKREGICAAVVGLPLQLDGMEGEMCAVVRSFVQKLIKKSGVYVYLHDERFTTAMASRTTESLGLRRKASQKVDDKISAALILQQVLDMAKGRGII
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SQUT_SALTY
Sequence: MNNYTIKDITRASGGFAMLAVDQREAMRLMFAAAGAKTPVADSVLTDFKVNAAKILSPYASAVLLDQQFCYRQAVEQNAVAKSCAMIVAADDFIPGNGIPVDNVVLDKKINAQAVKRDGAKALKLLVLWRSDEDAQQRLNMVKEFNELCHSNGLLSIIEPVVRPPRCGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGARSDLLTASQRLNGHINMPWVILSSGVDEKLFPRAVRVAMEAGASGFLAGRAVWSSVIGLPDTELMLRDVSAPKLQRLGEIVDEMMAKRR
What is the function of this protein?
Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).
What are the official names of this protein?
Sulfofructosephosphate aldolase, SFP aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: LYRM7_DICDI
Sequence: MNRAKVLSSYLGLLRTEKKVFQNDKRALEHVINLTRVQFRDNKNETDNTKINEMIDHANAVSHFLVKDLIQGVRKDEKTIQLKFDENTKSYQQYEFVNDQPPQRKKRGKIQIDDEQPTTCCGGGCGKPMPSNNSEKSTCS
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane (By similarity).
What are the official names of this protein?
Complex III assembly factor LYRM7, LYR motif-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y209_MYCGE
Sequence: MKQCFVVTTTKRLDSLLASLLNLSRVKVVKLIMNGQIKVNEKLTFKNSLIVAKDDVIKVEIHDETTSDFITSVEPYNLKLEVLFEDKDLMVINKPSGLLTHPTTFNEKASLLAACIFHNNKNPVYLVHRLDRDTSGAIVVCKNQASLLNLQNQLQNRTLKRYYVALVHFPFNALTGSINAPLARVNNNKVMFKIAQTAKAKQAITKFKVINQNEKAALISLELLTGRTHQIRVHLKFIQHPVYNDPLYGIKSEKKDSYGQFLHANRICFIHPTLNKPMDFHAPLEPKFSTKLKSLNLSLTDPLHVLFK
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase MG209, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: TRMFO_DESHY
Sequence: MSAIKVIGAGLAGAEAAWQIARQGIEVELYEMRPVQMTPAHHTGHFAELVCSNSLKGAGLDNAAGLLKEEMRRLDSLLMRVADQYAVPAGGALAVDREQFSQEITKLLQEHPLIQVHREEVKSLPQAGIAVIATGPLTAEGLAREIQKMTGEDALAFYDAAAPIVTLESINLEKAFWASRYDKGDPDYLNCPMTEEEYKRFYHELLKAETAEVKGFEKGKVFEGCMPVEVMAARGEQTLTFGPLKPVGLIDARTGQRSYAVVQLRKENRAGTLFNLVGFQTHLKWGEQQRVFRLIPGLENAEFVRFGVMHRNTFLNAPKVLKADYSLQKTPQLFFAGQITGVEGYVESTASGLVAGLNAVRRLKNLPTLIFPQETALGALARHLEGSPSVDFQPMSINYGLLPPLEVRIKAKKEKNAKISARALAKLEEFKAAEGLD
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_CYAM1
Sequence: MKELVQQLRKDTGAGVMDCKKALQEANGDVVQALNLLKKKGLAKAEQKRTRSTTNGRVESYVHAGNRLGVLLELNCETDFVAKSEPFQLLAKNLAMQIAACEQVRYIEWEQIPSSVIESVKSQVAEQLVEQLANKPVQLRSQIVEAKVKKQLQKQCLLDQPFIKDEQLTVDEVIRTTIAQVGENIRLKRFARFVLGEETGEETGEETND
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, chloroplastic, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACPS_BURL3
Sequence: MAIYGIGTDIAQVSRIAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWRALQTLNHPSGEPYVVASGELADWLAARGITARVTVSDERDYAVSFVVAETDAAPAPVSRTSS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAW_BACC4
Sequence: MERTIGIDAGGTLTKIAYFNKKKLLTFEKFYSHEQHKIIDWIKNNNGIKQICITGGKSKLLQQLLTGSYKIIELSEFEATLAGVQFILKEEQHTINNFILTNIGTGTSIHYVYNEQYIRAGGTGVGGGTIMGLSKLLTNIDHFEDIIPLTKVGSRKELDITVGDIYGGILSPIDNNLTASNFGKAAITESNNSSSDILATVQGLVGEVVTALSLQFAETKNIEHIIYIGSTLCNNVQLQHIISSYTEYQNKTPIFLQDGGNSGAIGALLHATK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type II pantothenate kinase, PanK-II, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type II pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL24_SHV21
Sequence: MLSVIKQRDKEVLAHLPNKRKIAGNKAHLETYKKLAKYTVSASIFKFLSISHPCPLRAKTRLFFEVSLGNRIADCVMLTSCGETRICYVIELKTCMTSNLDLISDIRKSQRSQGLCQLADTVNFIHNYAPLGRQAWTVLPILIFKSQKTLKTLHIETPKFPVNLTHTSEEKLSCFLWSRADVEIRKKIHLAPKPKRIFKWDSLLDSTSTEHSAYRQKLIERNKKKCFTLQNQTSKFRDRTNKKSNDQLRARQANARPCKKKQHNNKRLRNNRKHGGKVSRLTTTTSFSSEAAFSNYPVSTHKL
What is the function of this protein?
May participate in nuclear egress of viral particles.  Plays a role in the dispersal of several host nucleolar proteins including NCL/nucleolin and NPM1.  Since deletion of host NCL/nucleolin negatively impact on nuclear egress, UL24 supposedly acts on this process through its effect on host nucleoli (By similarity).
What are the official names of this protein?
Protein UL24 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL24 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus, host nucleolus. Host Golgi apparatus.
Protein: RS7_COXB1
Sequence: MARRKAAPKRETLPDPLFHSELLAKFINAVMRNGKKSVAEKIVYGALDVVAKRVQNKSGEQGDGDGESGGKAGGIKKRSLGDIRTDENARALALETFKGALDKVMPNVEVKSRRVGGSTYQVPVEIRMARRQALARRWLVEYANKRNEKTMVLRLAHEILDAVEGRGGAIKKREDVHRMAKANQAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SDHD_PSEA7
Sequence: MILGTPKADWLAEFPRLADLIALRPSEWFNPAIAPSAEALADVGLGAADVADASARLQRFAPLIARLFPETAGSGGIIESDLVEVADFHDALRQHYAAELPGRLWLKRDSHLPISGSIKARGGIYEVLAHAERLALENGLVGLDDDYSRLAEPDCRAFFAGHRIAVGSTGNLGLSIGIIGAALGFQASVHMSADARQWKKDKLRAHGVTVVEYASDYSVAVEQGRREAAGDPYTHFVDDENSRDLFLGYAVAAERLRGQLDAAGIRVDSEHPLFVHLPCGVGGGPGGVAFGLKLAFGDAVHCLFAEPTHSPCMFLGVYTGRHEQVSVQDFGIDNRTAADGLAVGRPSGFVGRAMQRLLDGYYTVDDDELFRLLALLERSQGIRLEPSALAGAPGIARVTREPQGYRERMGLTSARLANATHLVWATGGGMVPEAEMHAYLERGRALLD
What are the official names of this protein?
Probable D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: RL33_BURP6
Sequence: MAKGARDKIKLESTAGTGHFYTTTKNKRNMPEKMEIMKFDPVARKHVAYKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: THIE_PHOLL
Sequence: MNNLPNAPFAPTEHRLGLYPVVDSLAWISRLLQTGVTTIQLRIKDLPEDQVEEEIQQAIMLGRQYNARLFINDYWRLAIKHGAYGVHLGQEDLVIADLNAIQKTGLRLGISTHDEQELARAKSLRPSYIALGHIFPTTTKAMPSSPQGVEALKRQVENTPDYSTVAIGGISLERVPDVIATGVGSVALVSAITKAKDWRQATAQLLYLVEGIELKG
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: NUOD_SULNB
Sequence: MQQPNKLTPFFENLNFERDDNTMVINFGPQHPSAHGQLRLVLELEGEQVVKAYPDIGYLHRGIEKMAENMTYNEFLPTTDRLDYIASTANNYAYALAVEKLLGIEAPRRAQVIRTMLLEINRLISHLFFIATHALDVGAMSVFLYAFREREFGMDLMEDYCGARLTHSAVRIGGVPLDLPNGWIEKMISWCDKVDHELEHTYNALLQENRIWKMRLEDVGVISAEDALSWGCTGPMLRGSGVNWDIRKEEPYELYGELDFDIPVSDRCDSYGRYRLYMEEMHQSTRILRQLVSKYKESEPQLMAHAPQYISAPKEEIMTQNYALMQHFVLVTQGMRPPKGEVYVPTESPKGELGFYIKSEGEPYAYRLKCRAPSFFHTGLLQEILVGTYIADVVTIIGSTNIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KITH_EHV1B
Sequence: MAARVPSGEARRSASGAPVRRQVTIVRIYLDGVYGIGKSTTGRVMASAASGGSPTLYFPEPMAYWRTLFEADVISGIYDTQNRKQQGDLAADDAASITAHYQSRFTTPYLILHDHTFGLFGGDSLQRGTRPDLTVVFDRHPVASAVCFPAARYLIGDMSMCALIAMVATLPREPQGGNIVVTTLNVDEHVRRLRTRARIGEQIDMKLIATLRNVYSMLANTSNFLRSGRVWRDGWGELPLSCETYKHRATQMDAFQERESPELSDTLFAMFKTPELLDDRGVILEVHAWALDALMLKLRNLSVFCADLSGTPRQCAATVESLIPLMSSTLSDSESASSLERAARTFNAEMGV
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: HIS3_PSE14
Sequence: MKDWLDEIHWNSDGLVPAIAQDHKTGRVLMMAWMNREALSLTASENRAIYWSRSRGKLWRKGEESGHVQKLHELRLDCDADVIILMVEQIGGIACHTGRESCFYRVYENSGWKTVDPVLKDPDAIYSAGH
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHKF_DICDI
Sequence: MILKFIIQQCVFKVAKIFSDNLIQIFMDISSVYSSSTLFFSKLSLLMCKVFNSKCAGISVLNKDGLFDTIAFCSSTQELENFSYSLKKISKNITYYDNINEIFNNSEIIKKYNLKSYMEIPLKDSKEFYFGDIVLFGDQTLNPNILDTNILTFITNRTSMEFEKKKVSDQLIIAKNLLDQSPSCSCLVSRNGKIIRKIGAFYERLLGLEIGENISSVEKSSDISTILKQVCFENNNLSTETTITKKNGEKYPAEVFVKEISDIHSNSIGIMIIVRDITDQIRLKEMNIELQKKSELEQKRNQELMEARDLALTATKIKSQFLATISHEIRTPLNGIITMGEMLLSTSPLNTEQHDIAETIFGSSELLLSITSDILDFSKIEASKLELEMIEFDFIGCLEGIGKTIGVSITNKPIEIAFLMDTDIPHRLIGDPNRLIQIMLNMGTNAVKYTDRGHIVFRISVISREQNRCKIKISIDDSGIGIGEDQRAHLFEPFHQIDSSSTRKYGGSGLGLAISSKLAKLMGGEVILERSKPGVGSLFSVTLNFEQIGSNTLKSLLPDKSFSRNKTCIILDNYEYTASIASQRFDQIFEESNIILVKESTVKKFFELVQEYKINGDVNKIDLKNLDPELLPFFDSSLICIIVFHRFMDNLDIFLKYVKDFIEFYKKKIVVALGINHKNFKNLPKRRDFLIFKKPISSTNLIKVSNMARKIIPKSSSSSNLIQTISQIDNQQQQQQQQLQQQEQEQQHQQQQLQQEQQFVTISPHSDSSEKKTTPKKDRGKYDFNISPLRIDRFGTESTSSPKIKLYSDTSSDSGESDEFEFSENLRELKSDGELVVLKNQPYKEQRLSNIQLINDPIVTPPTPKANSEVVSTKAESTFFQSSSITIKETRSDSVNSVNSVNSVNSVNSLNSENSNNSLDVGIRTRPRILLVDDNAVNRKVVKLQLKKLGYDCDTATNGFEGFEMQKKDNYELIFMDLNMPLCDGSMASKLIRSHEELNNYKSRANIVGLSATYLHGSKDYCVSMGMDDFVVKPLKLQPLGELVKKYLEVENNNNNNNNNNNNNNNNNSNNNNSNSNSNPNSNSNSNSNSNSNPNQNPNYCNNLPTDFI
What is the function of this protein?
Acts as a receptor histidine kinase for a signal transduction pathway.  This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
What are the official names of this protein?
Hybrid signal transduction histidine kinase F.
Protein: Y1831_MYCTO
Sequence: MRLCVCSAVDWTTHRSSAGEFCGCQLRTPKEQYLSVNLSGTRTARDYDASGKRWRPLAVLTRRWGKAIHLTVDRVAESLRRLACR
What are the official names of this protein?
Uncharacterized protein MT1879.1.
Protein: RR8_POPAL
Sequence: MGRDTLADIITSIRNADMDRKGTVRIPSTNITENIIKILLREGFIENVRKHQEGNFFFFALTLRHRRNRKGPCRTSLNLKRISRPGLRIYSNYQQIPRILGGMGIVILSTSRGIMTDREARLERIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HEM2_RAT
Sequence: MHHQSVLHSGYFHPLLRAWQTTPSTVSATNLIYPIFVTDVPDDVQPIASLPGVARYGVNQLEEMLRPLVEAGLRCVLIFGVPSRVPKDEQGSAADSEDSPTIEAVRLLRKTFPTLLVACDVCLCPYTSHGHCGLLSENGAFLAEESRQRLAEVALAYAKAGCQVVAPSDMMDGRVEAIKAALLKHGLGNRVSVMSYSAKFASCFYGPFRDAAQSSPAFGDRRCYQLPPGARGLALRAVARDIQEGADILMVKPGLPYLDMVQEVKDKHPELPLAVYQVSGEFAMLWHGAKAGAFDLRTAVLESMTAFRRAGADIIITYFAPQLLKWLKEE
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: TC3A_CAEEL
Sequence: MPRGSALSDTERAQLDVMKLLNVSLHEMSRKISRSRHCIREYLKDPVSYGTSKRAPRRKALSVRDERNVIRAASNSCKTARDIRNELQLSASKRTILNVIKRSGVIVRQKLRPAPLLSADHKLKRLEFAKNNMGTNWSKVVFSDEKKFNLDGPDGCRYYWRDLRKEPMVFSRRNFGGGTVMVWGAFTEKKKLEIQFVSSKMNSTDYQNVLELELSKYLRHYSRKDFRFQQDNATIHVSNSTRDYFKLKKINLLDWPARSPDLNPIENLWGILVRIVYAQNKTYPTVASLKQGILDAWKSIPDNQLKSLVRSMEDRLIEIIRTQGNPINY
What is the function of this protein?
Binds specifically to the terminal nucleotides of the TC3 inverted repeat.  Its expression results in frequent excision and transposition of endogenous TC3 elements.  TC3 transposase acts by making double strand breaks at the ends of TC3 element.  The excised element would then be inserted into a target sequence.
What are the official names of this protein?
Transposable element Tc3 transposase.
What is the protein family that this protein belongs to?
Belongs to the transposase 5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HMUV_PECAS
Sequence: MTDSALDRTLVARHLRFQTNGRYLTDDVSLELNCGEIVAIIGPNGAGKSTLLRLLTGYLTPDDGECLLAGQPFSHWQPSALAKTRAVMRQHSGMAFAFSVQDVVAMGRSPHGRYPKNDDVVQQVMAQTGCLELATRDYRHLSGGEQQRVQLARVLAQLWHPEPTPGWLFLDEPTSALDLYHQQHLLRLLKQLTREQPLAVCCVLHDLNLAALYADRILLLHEGKLVAQGSPADVLQAETLAHWYRADLSVGSHPDYAIPQVYLRQ
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SCOP2_ARATH
Sequence: MANNLGLVILLLVIVLVSCSKSSDCALASPQKSRPSSEWRRKLIPVRSSRSPRSPSFAPKKPPPPPPSPPLSPSSPPSN
What is the function of this protein?
Brassicaceae-specific phytocytokine (plant endogenous peptide released into the apoplast) perceived by MIK2 in a BAK1/SERK3 and SERK4 coreceptors-dependent manner, that modulates various physiological and antimicrobial processes including growth prevention and reactive oxygen species (ROS) response regulation.
What are the official names of this protein?
Serine rich endogenous peptide 2, AtSCOOP2, Phytocytokine SCOOP2, Precursor of serine rich endogenous peptide phytocytokine 2.
What is the protein family that this protein belongs to?
Belongs to the serine rich endogenous peptide (SCOOP) phytocytokine family.