PharMolix/UniProtQA huggingface dataset:
Protein: COHA1_MOUSE
Sequence: MDVTKKSKRDGTEVTERIVTETVTTRLTSLPPKGSTSNGYAKTGSLGGGSRLEKQSLTHGSSGYINSSGSIRGNASTSSYRRTHSPASTLPNSPGSTFERKAHMTRHGTYEGSSSGNSSPEYPRKELASSSTRGRSQTRESEIRVRLQSASPSTRWTELDEVKRLLKGSRSASASPTRNTSNTLPIPKKGTVETKTVTASSHSVSGTYDSAILDTNFPPHMWSSTLPAGSSLGTYQNNITAQSTSLLNTNAYSTGSVFGVPNNMASCSPTLHPGLSSCSSVFGMQNNLAPSSSVLSHGTTTASTAYGAKKNVPQPPTVTSTGVSTSATCTTSVQSDDLLHKDCKFLILEKDNTPAKKEMELLIMTKDSGKVFTASPATISSTSFSEDTLKKEKQAAYAADTCLKADVNGDLNTVSTKSKMTSAENHGYDRGGGGGRGKGGGAGGGGGGGGASGGGGAWGAAPAWCPCGSCCSWWKWLLGLLLTWLLLLGLLFGLIALAEEVRKLKARVEELEKTKVLYHDVQMDKSNRDRLQAEAPSLGPGLGKAELDGYSQEAIWLFVRNKLMTEQENGNLRGSPGPKGDMGSQGPKGDRGLPGTPGIPGPLGHPGPEGPKGQKGSIGDPGMEGPIGQRGLAGPMGPRGEPGPPGSGEKGDRGIAGEQGPQGLPGVPGPPGLRGHSGSPGPQGPPGAVGPQGLRGDVGLPGVKGDKGLMGPPGPKGDQGEKGPRGLTGEPGIRGLPGAVGEPGAKGAMGPAGADGQQGSRGEQGLTGMPGTRGPPGPAGDPGKPGLTGPQGPQGLPGSPGRPGTKGEPGAPGRVMTSEGSSTITVPGPPGPPGAMGPPGPPGTPGPAGPAGLPGQQGPRGEPGLAGDSFLSSGSSISEVLSAQGVDLRGPPGPPGPRGPPGPSIPGPPGPRGPPGEGVPGPPGPPGSFLTDSETFFTGPPGPPGPPGPKGDQGDPGVPGTPGISGGLSHGASSSTLYMQGPPGPPGPPGPPGSLSSSGQDIQHYIAEYMQSDNIRTYLSGVQGPPGPPGPPGPVITITGETFDYSQLASQVVSYLRSSGYGAGLSSASSSEDILAMLRRNDVWQYLRQNLVGPPGPPGPPGVSGDGSLLSLDYGELSRHILNYMSSSGISFGHPGPPGPPGLPGTSYEELLTMLRGSDYRNIIGPPGPPGPPGMPGNAWSSISVEDLSSYLHTAGLSSIPGPPGPPGPPGPRGPPGVSAALSTYAAENSDNFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDGHLRENYNWSSNSSARRGTSYSSSTGTGGTNGGSLGEGGAYGAGDGGPYGTDIGPGGGYGAAAGGGIYGTNGDSFRDGFTGDLDYNKLAVRVSESMQRQGLLQGMAYTVQGPPGPQGPPGISRVFSAYSNVTQDLMDFFQTYGTIPGPPGQKGDVGTPGPKGDRGPAGPRGPPGPPGPRGNKGEKGDKGDQVYTGRRKRSIAIKP
What is the function of this protein?
The 120 kDa linear IgA disease antigen homolog is an anchoring filament component involved in dermal-epidermal cohesion.
What are the official names of this protein?
Collagen alpha-1(XVII) chain, 180 kDa bullous pemphigoid antigen 2, Bullous pemphigoid antigen 2.
What are the subcellular locations of this protein?
Cell junction, hemidesmosome. Membrane; Single- pass type II membrane protein. Note=Localized along the plasma membrane of the hemidesmosome. SUBCELLULAR LOCATION: [120 kDa linear IgA disease antigen homolog]: Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: PDXY_MANSM
Sequence: MKNVLSIQSHVVFGYAGNKSATFPMQLMGVDVWALNTVQFSNHTQYGKWTGMVIPKEQIGEIIRGIDEIGELKNCNAVVSGYLGSAEQVDEIIKAVEKVKSLNPQALYLCDPVMGHPDKGCIVADGVKEGLINLAVSHADILTPNLVELREISGLPVENFEQAIEAVKVIRAKGPKTVLIKHLSKVGKYADKFEMLLANDEGIWHLTRPLYTFAKEPVGVGDLTAGLFLANKVNGKSDLEAFEHMANAVNEVMKTTFELNSYELQLIAARKLIVNPVSSVKAVKIA
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: Y212_HELPG
Sequence: MKKPYRKISDYAIVGGLSALVMVSIVGCKSNADDKPKEQSSLSQSVQKGAFVILEEQKDKSYKVVEEYPSSRTHIIVRDLQGNERVLSNEEIQKLIKEEEAKIDNGTSKLVQPNNGGGSNEGSGFGLGSAILGSAAGAILGSYIGNKLFNNPNYQQNAQRTYKSPQAYQRSQNSFSKSAPSASSMGGASKGQSGFFGSSRPTSSPAVSSGTRGFNS
What are the official names of this protein?
UPF0323 lipoprotein HPG27_212.
What is the protein family that this protein belongs to?
Belongs to the UPF0323 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y277_ATV
Sequence: MVTTSPPPTLTNSVQPHPTTTTTTTLLPVTNLIPIILVSVFIALLLIFLLSRTSKKQPDPYLGVMSAISKHIRKKKAIALVFYIDTTDQRIKIYPVFQKVGNVLIYLNENGETNFSVIDPKTKPLQIKVGNISYPVYFAIAGNTIKYLAKFEDLETGVKYDNISIDDPRLIEILSKITGDVTSTYYITPTKKLTILASPEAIASVTIKRLWSPIENSIITIKEINENLTKLMEISARVLGLRLNTRLTLILMLIAVFLIFMVLIGTGIVHFPPPPTK
What are the official names of this protein?
Uncharacterized protein ORF277.
Protein: PYRB_RHIEC
Sequence: MVFFPHRHLIGIKGLTEQDITYLLDKADEAVKISRRREKKTSTLRGLTQINLFFEASTRTQASFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMRPDVLVIRHSSAGAAALLAQKVSCSVVNAGDGQHEHPTQALLDALTIRRAKGKLSRIIVAICGDVLHSRVARSNILLLNAMGARVRVVAPATLLPAGIAEMGVEVFHSMKEGLKDADVVMMLRLQRERMSGAFVPSVREYYHFYGLDAETLKAAKDDALVMHPGPMNRGVEIASEVADGPQSVIAEQVEMGVAVRMAVMETLLVSQNQGPRTDGMMA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PRI2_HUMAN
Sequence: MEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYSTQGNVGKISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIKGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCLKIILSNPPSQGDYHGCPFRHSDPELLKQKLQSYKISPGGISQILDLVKGTHYQVACQKYFEMIHNVDDCGFSLNHPNQFFCESQRILNGGKDIKKEPIQPETPQPKPSVQKTKDASSALASLNSSLEMDMEGLEDYFSEDS
What is the function of this protein?
Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis (PubMed:9705292, PubMed:17893144, PubMed:25550159, PubMed:26975377).  During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity).  The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands (PubMed:17893144).  These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively (By similarity).  In the primase complex, both subunits are necessary for the initial di-nucleotide formation, but the extension of the primer depends only on the catalytic subunit (PubMed:17893144, PubMed:25550159).  Binds RNA:DNA duplex and coordinates the catalytic activities of PRIM1 and POLA2 during primase-to-polymerase switch.
What are the official names of this protein?
DNA primase large subunit, DNA primase 58 kDa subunit, p58.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase large subunit family.
Protein: FOLD_CHLT2
Sequence: MLLKGAPAADHILATIKENIRACSKAPGLAVVLIGNNPASEIYVNMKIKRATDLGMVSKSYRKPSDATLSDILALIHQLNNDENIHGILVQLPLPKHLDAQAILSTITPDKDVDGLHPVNVGKLLLGETDGFIPCTPAGIVELCKYYEIPLHGKHVVILGRSNIVGKPLAALLMQRHADTNASVTLLHSQSEHLTEITRTADILISAIGVPLFVNKEMIAEKTVIMDVGTSRIPAANPKGYILVGDVDFNNVVPVCRAITPVPGGVGPMTVAMLMRNTWESFLRHTS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SRB8_YARLI
Sequence: MNSSAPSPGPSSRLYRSINSRDDLSQQRYVLRPPDDIHPLVDPARIGDSVYPDFYPWKRSTDEEDARMVDNLQKGYAEPPSVPHESQSAKKSIASLLRIKSNMTALSCFIITAMHIRVDTCRITTPGTFKPPPRVTLTDHKREAWLKDLANPAVPLRKLSRTIPHGIRNKVLLDQCCAKRIAPSRAVWFARCVGANELRGLKRKGHHQMGNMSEAIWLQEWTECVVDVLQRSSVAFLRAEGEPQARQTAKQNFAYMWVVGLLSDDNTKDTKAGSGVAPGTGASTTSKLSSVEKLPVAILIIRTFWKPLLTFPNLAKKLAQNLLAELSKLEADAHSDKPFYQPTIKALSTLVNALFDAQPDAFVMPSKWVQLGSTFEAIVSDSESTRVRNEALVISDTPKTRRTRNKQAVIISILDAARAPFDKTLFNQIVDTRADFGTIIQTILAWAVSDSRVSVERVFIASHLVSQLSEGVDGDAVPSHIVQFLLSVKSHLDVRIDDLYALVTELCVLDIFQPQDYVRSLISSGVLYISRLSEWANVQLDILGNLPLVAVPSSCQVQVRYMVRKVAKYASYNENELLERTNNALRVLLPGVFDSQAEDVDMSSSSSSLSDSTNIPYSEFTQNTRIVVAENLYTSLCAAVERGYVPTTQEFAQYQLILENLHAWRLMCASIQLIVPKCTQSHLLYFLASATRYQWQAFACIADMPALVKVFMHQYRGLRKVRVSRELWDLVQFSAQQLPELKPELETLLKNSSSPQLSPISEVTPQTDSEATKDVNLPQALNDLLLHSSDVRTSCKMLANYKDDSQFSNQLMTWLRDQEVSLQLLQTLVFLVVYECTCIEKVGDLFLQIHNLRDMSGGSRLLLSLIARDLTQEYSLSTTEAFSLQFQRKLFADQHPRIYLRLVAQYLFEREVFQDPQWLDDVDTFCKEVAVHHPALFSQLIVDPVIEPDNAVAASSLQQLLNHLLKLDLGTGTSLADDLQQLITHVTPFNMFLAQTQLRLLFAHRGRISKDPVAMDTSPELTINSTTPSTDTTDEDVSVLFRVLSDPGLLKLPPFFGDLFSELPGELKGRILARAETTFLTSPNFPRVGEDNIVSLLIELADSLADSVTEDVCKTQTFALSSGLQRLVEASVREPHPPGLAEGISMFLKIAMIHEKSLMASEDAEVTMLRNHVVEGLQALLDSPFVATTPDLKATLQDTWTALKSELSEVAEPANSAPSKAGPTRDLLLYSTANDAFSEVTVRSFDLLEESNPTMGVNDAALNLALFNATIEKRIPIAWNNGHKRQLVDGGRGGRKTARGTDSSLVPTILEGIPRCMDEYSNHWELFFCFYLYTMRASEVHDLRANRASSFERRASSVELLA
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EX7L_HELPH
Sequence: MDVLSVSEINAQIKALLEATFLQVRVQGEVSNLTIHKVSGHAYFSLKDSQSVIRCVLFKGNANRLKFALKEGQEMVVFGGISVYVPRGDYQINCFEIEPKEIGSLTLALEQLKEKLRLKGYFDKENKLPKPHFPKRVAVITSQNSAAWADMQKIASKRWPICELVCINTLMQGEGCVQSVVESIAYADSFHDTRNAFDAIVVARGGGSMEDLYSFNDEKIADALYLAKTFSMSAIGHESDFLLSDLVADLRASTPSNAMEILLPSSDEWLQRLDGFNVKLHRSFKILLHQKKAHLEHLADFLKRLSFENKHHLNALKLEQLKIALENKTLEFLRFKKTLLEKISTQALTSPFLQTKTERLNRLENALKLAHANLKLPQFGAFLSKNNQAIELEALKAGDKIELSNEKARASAEILSVDRV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_YERPY
Sequence: MTTKRKAYVRTMAPNWWQQLGFYRFYMLREGTSIPAVWFSVLLIYGVFALKSGPAGWEGFVSFLQNPLVLFLNILTLFAALLHTKTWFELAPKAVNIIVKSEKMGPEPMIKALWVVTVVASAIILAVALL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NACA_ASPCL
Sequence: MADPRVEELPDEEVPKTNVEDAGSDSESEAGEESSIPSGAAVTIHSRNEKKARKAIGKLGLKHVPGITRVTLRRPKNILFVINQPDVYRSPTSNTWIIFGEAKIEDLNSQAQASAAQQLAAAEAAAGEHAGHDHDHDHGKGKAPETEAKKEEEEDDGEEVDETGLEAKDIELVMAQANVSRKKAVKALRENDNDIVNSIMALSI
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  Egd2 may also be involved in transcription regulation (By similarity).
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: NEMA7_LINRU
Sequence: GCIPVGSMCTISNGCCTKNCGWNFHCNKPNQ
What is the function of this protein?
Potent toxin against insect sodium channel (Nav) and 5- to 100-fold less potent against mammalian sodium channels (By similarity).  Potently inhibits inactivation of insect sodium channels of B. germanica (BgNav1) (EC(50)=9. 5 nM) (PubMed:34445875).  The toxin also delays the inactivation of most mammalian Nav (hNav1. 1/SCN1A; EC(50)=171. 5 nM, rNav1. 2/SCN2A; EC(50)=50. 4 nM, rNav1. 3/SCN3A; EC(50)=170. 2 nM, rNav1. 4/SCN4A; EC(50)=810. 6 nM, hNav1. 5/SCN5A; EC(50)=155. 6 nM, mNav1. 6/SCN8A; EC(50)=147. 6 nM, hNav1. 9/SCN9A; EC(50)=129 nM) (PubMed:34445875).  1 uM is enough to completely inhibits the inactivation, resulting in sustained non-inactivating currents (By similarity).  In addition, the toxin significantly enhances the recovery from inactivation, and the open state is not required for the toxin to interact with the channel (By similarity).  In vivo, injection into brine shrimp (Artemia salina) stops movement or causes death after 24 hours (EC(50)=6. 1 uM) (PubMed:34445875).
What are the official names of this protein?
Nemertide alpha-7.
What is the protein family that this protein belongs to?
Belongs to the nemertide family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_PROM0
Sequence: MKETIEFLIDTVEARQVLDSRGNPTVEAEVFLECGASGRAIVPSGASTGAHEAHELRDGGSKYMGKGVLNAVNKIHETISPALCGLSSLDQIAVDKLMIEIDGTPNKSNLGANSILAVSLATARASANALDIPLYRYLGDPLSNLLPVPLMNVINGGAHAPNSLDFQEFMLVPHGVNNFSESLRMGTEIFHSLKSLLDQKGLSTAVGDEGGFAPNLSSSEEAGDLLLEAIQKAGFKPGEQVSLALDAASTEFYSDGIYKYEGKSLNSSEMISYLSRLVSNYPIVSIEDGLAEDDWEGWSELNKELGNKVQLVGDDLFVTNTERLRKGIMEKSANSILIKVNQIGTLTETLEAIELAKMSGFTSVISHRSGETEDTTIADLSVATRSGQIKTGSLSRSERIAKYNRLLKIEEELGNQARFAGALGLGPKNI
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: LOLD_FRATO
Sequence: MNDVVLSCKNVSKKYTEFKTDIAILKDVNLEIKKGEKVAILGLSGSGKTTLLNVLGGLDKCSAGEVYLMGERFDNQSVNKRAKMRNKHLGFIYQLHHLLPEFTAIENVMIPLAITKKYTKKESIKLANEILKKVGLDHRADHKPAELSGGERQRVAIARALVTNPNCILADEPTGNLDSQRSESIFALMQQLSDDFGISFVIVTHDEKLASRMNKIYRLVDGELELVINSN
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UFC1_DROPS
Sequence: MVDDSTRKTLSNIPLLQIRAGPREKDVWVQRLKEEYHALIMYVKNNKQSGSDWFRLESNKEGTKWFGKCWYMHNLLKYEFDVEFDIPVTYPTTAPEIALPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGIAHAMALGLAPWLAVEVPDLIEKGIITYKEK
What is the function of this protein?
E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: RAG3F_ARATH
Sequence: MPSRRRTLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVQFEDRLFTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNSMKSFENLNNWREEFLIQASPSDPENFPFVLIGNKVDVDDGNSRVVSEKKAKAWCASKGNIPYFETSAKVGTNVEEAFQCIAKDALKSGEEEELYLPDTIDVGTSNQQRSTGCEC
What is the function of this protein?
Essential for trafficking from prevacuolar compartments to vacuoles.  Involved in the trafficking of newly synthesized protein to vacuoles.  Essential for plant growth (PubMed:24824487).  Participates in the recruitment of the core retromer components to the endosomal membrane by interacting with VPS35A (PubMed:23362252).
What are the official names of this protein?
Ras-related protein RABG3f, AtRABG3f, Ras-related protein Rab71, AtRab71, Ras-related protein Rab7B, AtRab7B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor; Cytoplasmic side. Prevacuolar compartment membrane; Lipid-anchor. Note=Partial co-localization with VPS3 at cytoplasmic punctate structures, and with VPS39 at subdomains of the vacuolar membrane. Co-localizes with VPS18.
Protein: TRM1_GAHVM
Sequence: MLGMSHNRLQSQGTEHDKFATQKLFAIWGQIQSYLFQVELLKRCDPTVGVRMINRLKLNVLMIYYLEKKMVPALKEQREMNLTPLTYGLWLALRRAKLEGELLLDALCEFKDGGNLRDFFRKSMSMCGDCPYHSTVELDTYGGKVSTEIKFLHDVENVLKQLNYCHLILKADTVENFMVSLDNYLLKTLGSGSVVPPELYDPSQPCSVCFEELCVTANSGDSTHKRIVRKICDHITKQINIRVNSDDMVTHLPHATYVPDDKRTTAQTALDVIQSTMRDTTTENDSNISVSKAAAAALDAHNVFLPASGDLYAISELQFWIASSGRKLHQPRGNTVESFADNLEALVSKERLFDLRTSIVETAVFDRRMDHFERVFAQEIEHMNAADRLLLGGRAAAPDDIIEALIKACYDHHMSAPLLKRLLYPDEAAHDALKTVLERVSSHCIGNDIQCQDGDGTCGERMNETGHFRTNDSFAMSTTSLGHDEWLEMVKSASSDVARRRKMYAERLTKKSLASLDKCITEQRHELEKMLRVNVYGEVLIDSYTALFNGFRSRKRLLEAVKNCCANIIDNRNSDDAFDAHRFMQTSLLKHRIDPAMLPSLTHKFFQLVNGPMFSHDRHRFAQPSNTALYFSVENVGLLPHLKEEMARFMFHSSRKTDWTVSKFRGFYDFSTIDNVTAAHRMAWKYIKELIFATALFSSVFKCGELHICRADSLQINSNGDYVWKNGIYITYETEYPLIMILGSESSTSETQNMTAIIDTDVFSLLYSILQYMAPVTADQVRVEQITNSHAPI
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: BPT_BRUA1
Sequence: MTHQPQQSPQFFLTAPSPCPYLEGQQERKVFTHLVGDKANEINDLLTQGGFRRSRNIAYRPACEVCRACISVRILAGEFEMTRNMRRVWSQNRDLIGRVHKAQPSTEQYALFRDYLDARHRSGGMSDMTVLDYAMMIEDTHVNTQIIEYRRRGPDSFMSAKGDGELIAVALTDVMADGLSMVYSFFLPHMQERSLGTYMILDHIERARAAGLPHVYLGYWVEGSRKMQYKIRFTPQEHLGPRGWQRFEG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_GEOSW
Sequence: MTNPKLVLAYSGGLDTSVAIKWLQERGYDVIACCLDLGEGKDLDFVKEKALKVGAIKSYVIDVKEEFADEYALIALQAHALYEGKYPLVSALSRPLIAKKLVEIAELEGAVAVAHGCTGKGNDQVRFEVSIKALNPNLEVIAPVREWSWSREEEIEYAKKHGIPIPVDLDSPFSIDQNLWGRSNECGILEDPWAAPPEEAYELTAALENTPDVPEIIEIGFEQGVPKTLNGKPYSLASLILELNAIAGKHGVGRIDHVENRLVGIKSREVYECPGAMTLIKAHKELEDLTLVKEVAHFKPIIEQKLAEVIYNGLWFSPIKDALVAFLKETQKNVTGVVRVKLFKGHAIIEGRKSEFSLYDEKLATYTADDQFDHQAAVGFISLYGLPTKVYSIVNNQKKVNV
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2190_LISMF
Sequence: MSEDKGMKDKAKGLKDKVVGDAKDKFGKATDDKGKQVEGKAQKAKGEVEDKTGDAKKKLSE
What are the official names of this protein?
UPF0337 protein LMOf2365_2190.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: S26A1_RAT
Sequence: MDASPEPPQKGGTLVLVRRQPPVSQGLLETLKARLKKSCTCSMPCAQALVQGLFPVIRWLPQYRLKEYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVNVGIFSLLCLMVGQVVDRELQLAGFDPSQDSLGPGNNDSTLNNTATLTVGLQDCGRDCHAIRIATALTLMAGLYQVLMGILRLGFVSTYLSQPLLDGFAMGASVTILTSQAKHLLGVRIPRHQGLGMVIHTWLSLLQNVGQANLCDVVTSAVCLAVLLTAKELSDRYRHYLKVPVPTELLVIVVATIASHFGQLHTRFGSSVAGNIPTGFVAPQIPDPKIMWSVALDAMSLALVGSAFSISLAEMFARSHGYSVSANQELLAVGCCNVLPAFFHCFATSAALSKTLVKIATGCQTQLSSVVSAAVVLLVLLVLAPLFHDLQRCVLACIIVVSLRGALRKVKDLPQLWRLSPADALVWVATAATCVLVSIEAGLLAGVFFSLLSLAGRTQRPRAALLARIGDSTFYEDAAEFEGLLPPPEVRVFRFTGPLYYANKDFFLRSLYSLTGLDAGYSATRKDRGTEVGVSNRSLVDRKDLGSVSSGDGLVVPLAFGFHTVVIDCAPLLFLDVAGMATLKDLRKNYRALDITLLLACCSPSVRDTLRKGGFLGEDQGTAEELLFPSVHSAVETACARREELMAADSAL
What is the function of this protein?
Sodium-independent sulfate anion transporter (PubMed:8300633, PubMed:3661708, PubMed:9689008, PubMed:16357056, PubMed:19369292, PubMed:21093948).  Can transport other anions including thiosulfate, bicarbonate and oxalate by mediating sulfate-oxalate, sulfate-bicarbonate, sulfate-thiosulfate and oxalate-bicarbonate anion exchange (PubMed:8300633, PubMed:3661708, PubMed:9689008, PubMed:16357056, PubMed:19369292, PubMed:21093948).
What are the official names of this protein?
Sulfate anion transporter 1, SAT-1, Canalicular sulfate transporter, Solute carrier family 26 member 1, Sulfate/carbonate antiporter.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein.
Protein: PRM1_LODEL
Sequence: MLRNYLDLPEILSQVYLNQYTILLVLVVVKLILLKESLIDAISKQIINDATCNDDNLQHILNGVHDAILKNIDKLQYSGIVFVVLILKTIRELTSFFIDLLLGTYVCLLTAVVVGTTEFAFDASESIIQAVNVTVVAAADEIEDGLRGLSNFINDLVTGFNAIRTFFTGSASTSDADLYRDRINLSLGNLKDKISIPSTVLMDIQNARNFSMNELENLNNETQSLVNSPFNLVINKLDAIKLEINRYDNSSLQPIQIRDACLQTVNRVQDSQTVLIKVVENVSKWFLIVLAIIIACSLAYAFYIELRRWKRLSEFINEGDVADSEVGYRNEHNIYDNALLYTMIKRFGISVNERVIWVISYMSSKMAGIVFAFGIIGIISAVLQLLMIYFVQQAVDDEISTMNNSNENFEMASSYIRSMNNYINTTQSSINDELFGDIIDTSTKVNNTIAEFVDNLDSAVHSIFGESIIASAVNTVVYCTIGRKLEKIEAGCNWLAENVKIDIPEVPSEILRELQNISFLQPQNLMENFKPILDLYRNSVHLELLISLIFLAVWALQLIIGLMILLARQGINASGAGGAGGAGGTGDAEGCDNYTDNKVILMRRVTPLQIGSPHSLTEKERQLYQFPISKPRFDRSSDTLSSFYPPTSTPGRIEYPLHI
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein PRM1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.