PharMolix/UniProtQA huggingface dataset:
Protein: CRFR2_RAT
Sequence: MDAALLLSLLEANCSLALAEELLLDGWGEPPDPEGPYSYCNTTLDQIGTCWPQSAPGALVERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEPILDDKQRKYDLHYRIALIINYLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNITWFLLQLIDHEVHEGNEVWCRCVTTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIIVAWAVGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYCFFNGEVRSALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV
What is the function of this protein?
G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3.  Has high affinity for UCN.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase.  Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
What are the official names of this protein?
Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
Protein: GMPPB_DICDI
Sequence: MKALILVGGFGTRLRPLTLSKPKPIVEFANKAMILHQIEALCKIGVNEVVLAVNYRPQLMSQYLEPYEKKLGIKISYSHETVPLGTAGPLALARDLLNDGEPFFVLNSDIICDFPFADLLAFHKSHGGEGTIMVTKVEEPSKYGVVVYKEENGQILKFVEKPQVYVGNKINAGVYIFNPTILDRIQPKPTSIEKEIFPAMAADSQLYCMQLEGFWMDVGQPKDFLSGMGLYLNSLKSKQPELLATGNGIIGPVLIDPSSVIEPGCLIGPNVTIGPNCVIQEGTRLVNTTVLEGTTIGKNSWIKSTIIGWNSSIGKWVRMENTSVLGEDVHVSDELYINGGKILPHKSITSSIPEPEIIM
What is the function of this protein?
Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids.
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase beta, GDP-mannose pyrophosphorylase B, GTP-mannose-1-phosphate guanylyltransferase beta.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: THII_STAHJ
Sequence: MEFDHLLVRYGELTLKGTNRKKFVNALKDNVIKSLQTIEGTHVKGKRDRMYISLTEEADAQEVINRLTKIFGIKSISPVHKTSQELDEIKKLCVDLAQDFKPGETFKIDVKRVDKSFPMDTYALQRELGGAILQATEDISVDVKQPDYNVRVEVRMDGVYVFTQIYEGAGGLPVGTGGKTLLMLSGGIDSPVAGMEIMKRGVYIEAIHFHSPPFTSEKAKDKVIELTRILSERVGPIKLHIVPFTELQKQINKVVHPRYTMTSTRRMMLRVADIVLEKVGANAIVNGENLGQVASQTLKSMYAINDVTSTPILRPLVSLDKEDIVKKAREIGTFDVSIQPYEDCCTIFTPKNPVTEPDFDKVIKYESVFNFDEMVQRAADNIETLTINKDYKSEKDQNTDALIDELF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FF21_SALEN
Sequence: ADPTPVSVSGGTIHFEGKLVNAAAXVSXXSAD
What are the official names of this protein?
Fimbrin sef21, SEF 21.
What are the subcellular locations of this protein?
Fimbrium.
Protein: RISB_CAMFF
Sequence: MNIIEGNLHLNGDEKVAIINGRFNHIITDRLVEGAKDAFLRHGGKEENLDLILVPGAFEIPMALEKVLSSGKWDAVCCVGAVIRGSTPHFDYVSAETTKGIANVTLKYGKPVTFGVLTVDSIEQAIERAGSKAGNKGFEAMTSVVELLNLYKNIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RNH_OLEA2
Sequence: MKQVDIFTDGSCLGNPGPGGWAAVLRYAGTQKELGGGFSGTTNNRMEILAVIEGLEALQEPCTVNLYTDSQYVRNAVEKKWLDSWQRNGWKTAARKPVKNKDLWLRLLPLLARHTVKFHWVRGHSGHPENELCDTIARGHASRGGLPPDTQAAG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_BURM7
Sequence: MFYSIVAIFVGAGFGALLRWFLSIGLNALLPEVPLGTLASNLIGGYLIGIAVVAFATRAGLPPEWRLFVITGFMGGLTTFSTYSVEVMTHAVQGEFGWALAVAALHLIGSFTLTGLGMWTARAWLAPA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYL_RICRO
Sequence: MNQIEQKWQYIWQEEKAFEVSNASSKPKYYVLEMLPYPSGKIHVGHVRNYSIGDVIARFMTMQGFNVLHPMGWDAFGLPAENAAINNNSHPKKWTYSNIKNMKKQLKSMGFSYDWSREINSCDPEYYKHEQKFFLELYERNLAYQKESFVNWDPVDNTVLANEQVVDGRGWRSGAIVAKRYLKQWFLKITDYAEELLNEIQNLKEWPEAVRSMQEKWIGKSIGANFHFKIKDNEETTIEVFSTKPETIFGASFIGIAFNHPIIERLVSKTPEILAFITQCSHITRSSKLEKAEKEGVFTGLFVTHPFDSNIVLPVIITNFVLMDYGTGAIFGCPAHDECDHELAVKMNLSIKQVIKADMDVQKTAYTEDGILINSDFLNGLTSNEAKQEVIREFEKLGIGKRSVNYRLKDWGISRQRFWGCPIPMIHCEICGIVPVPYKDLPVTLPDDVNFDGHGNPLDHHPSWKHVNCPKCDKPAVRETDTFDTFFESSWYFMRYCNSNATEMTDKKACDYWLPVDKYIGGIEHAVMHLLYARFFTKVMNEQNYVSVQEPFKGLFTQGMVLHATYKDEHNNWLYPEEVVKKGNEFFHKESNNRVVQGRIEKMSKSKKNLIDLETMQEQYGADAIRLFVLSDSPPEKDLEWSASGIEGCSRFINKLEYMFKAIDSLKDDVNSEVNKELNRLVHFTIKHVAEDIKHFALNRAIARMRELSNSISAEISKDKIDVKTVRHGFNVLVQLLNPFIPHITEEIWQKLGNKERLYNLSFPAFDESMLELDTYIMAVQVNGKLRDTYEFKTSVSEDEIKQVTVSLPKVQKFLEGKEPKKIILVPRKIVNILV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_AQUAE
Sequence: MREAEVFRETRETKIKLYINLDGSGNYEVNTPVGFLTHMLESFAKHGRFDLKVEAEGDVHVSHHHTVEDCGIVLGQAVLKALGDKKGIRRYGYSIIPMDEALVLSSIDISGRPLFFYEDKDLRGKITEFDFELIWEFFKGFALESRSTLHIKVLDGKILHHVAEACFKSFAITLKEAVKVEGSGVPSTKGVI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIME_BOVIN
Sequence: MKTLQSTLLLFLFVPLIKPAPPSQQDSRIIYDYGTDNLEETFFSQDYEDKYLDGKSTKEKETMIIVPDEKSFQLQKDETITPLPPKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFTGNLIEDIEDGTFSKLSLLEELTLAENQLLKLPVLPPKLTLFNAKYNKIKSRGIKANTFKKLHNLSFLYLDHNALESVPLNLPESLRVIHLQFNNITSITDDTFCKANDTSYIRDRIEEIRLEGNPVILGKHPNSFICLKRLPIGSYI
What is the function of this protein?
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
What are the official names of this protein?
Mimecan, Osteoglycin.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: DOG2_YEAST
Sequence: MPQFSVDLCLFDLDGTIVSTTTAAESAWKKLCRQHGVDPVELFKHSHGARSQEMMKKFFPKLDNTDNKGVLALEKDMADNYLDTVSLIPGAENLLLSLDVDTETQKKLPERKWAIVTSGSPYLAFSWFETILKNVGKPKVFITGFDVKNGKPDPEGYSRARDLLRQDLQLTGKQDLKYVVFEDAPVGIKAGKAMGAITVGITSSYDKSVLFDAGADYVVCDLTQVSVVKNNENGIVIQVNNPLTRD
What is the function of this protein?
Phosphatase that is active on 2-deoxy-D-glucose 6-phosphate (2-DOG-6P), but not very active on fructose-1-P.
What are the official names of this protein?
2-deoxyglucose-6-phosphate phosphatase 2, 2-DOG-6-P 2, 2-deoxyglucose-6-phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. DOG/GPP family.
Protein: DPY30_HUMAN
Sequence: MEPEQMLEGQTQVAENPHSEYGLTDNVERIVENEKINAEKSSKQKVDLQSLPTRAYLDQTVVPILLQGLAVLAKERPPNPIEFLASYLLKNKAQFEDRN
What is the function of this protein?
As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation.  Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.  May play some role in histone H3 acetylation.  In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci.  May also play an indirect or direct role in endosomal transport.
What are the official names of this protein?
Protein dpy-30 homolog, Dpy-30-like protein, Dpy-30L.
What is the protein family that this protein belongs to?
Belongs to the dpy-30 family.
What are the subcellular locations of this protein?
Nucleus. Golgi apparatus, trans-Golgi network. Note=Associated with chromatin at regions enriched in histone H3 trimethylated at 'Lys-4. Highly enriched in gene promoter regions and 5' UTRs, but not in downstream regions of genes or 3' UTRs (By similarity).
Protein: MUTS2_STAAM
Sequence: MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFHQINETCDTYDLYDNASYELQGIRSKISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERVLTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVANTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: ATPB_RICPU
Sequence: MTKNIGKITQIISAVVDVKFTNNSELPEILNALECYNDKQRIVLEVAQHIGDDTVRCIAMDSMEGLVRGVEVIDTGSPIRIPVGTETLGRIMNVVGEPIDGKGDIKSSNISSIYKPAPDFTNQSTERNILVTGIKVIDLLAPYTKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYTVFAGVGERTREGNDLYHEMIDSGVINLAEPEKSKVALVYGQMNEPPGARARVALSGLTIAESFRDMNEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGELQERITSTKYGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRQIAEFGIYPAVDPLDSNSQVLDPMIVGEEHYSVARQVQQVLQTYKSLQDIITILGMDELSEEDKLTVVRARKIQRFLSQPFHVAEVFTGAAGKFVNLADTIAGFKGLVEGKYDDLPEAAFYMVGTIDEAIEKAQTLK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GYRB_STAES
Sequence: MVNTLSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYASHIEVVIEKDNWIKVTDNGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNGTIYHQAYKQGVPQFDLKEIGDTDKTGTAIRFKADKEIFTETTVYNYETLQKRIRELAFLNKGIQITLKDEREEEVREDSYHYEGGIKSYVDLLNENKEPLHDEPIYIHQSKDDIEVEIALQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGTQSKIIKEDKDRLSGEDTREGLTAVVSIKHGDPQFEGQTKTKLGNSEVRQVVDRLFSEHFERFLYENPSVGRIIVEKGIMASRARVAAKKAREVTRRKSALDVSSLPGKLADCSSKNPEESEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGEFDISKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVFNDRELDKLKQELNPSPKWSIARYKGLGEMNADQLWETTMNPEHRSMLQVRLEDAIDADQTFEMLMGDVVENRRQFIEDNAVYANLDF
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_THESM
Sequence: MVKVDKEELTVIRKFEHIEHCLKKQVEAHVSTQFENIHFVHTSLPEIDKDEIDLSVEVLGRKFDYPIMIAGMTGGTKGSQLAGKINKTLAKAAQELNIPMGVGSQRAMIRKPETWESYYVRDVAPDIFLVGNLGAPQFAENMPNRYGVEEALKAVETIQADALAIHMNPLQESVQPEGDTQYKGVITALAELKGELSYPIIAKETGAGVSMEVAIKLESIGIDAIDVGGLGGTSWSSVEYYRAKDEKSKNLALKFWDWGIPTALSVAEVRYATGLPIIATGGIRDGIMIAKALALGANLAGVALPLLKPAVNGDVEGVIKILQQYIDELRNVMFLVGAGSVKELKKVPIVVTGFAREWLEQRIDLWEFLRDRRL
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3894_BACC7
Sequence: MLEKTTRMNYLFDFYQSLLTQKQRSYMSLYYLDDLSLGEIAEEFDVSRQAVYDNIKRTEAMLEEYEEKLVLLQKFQERQRLVAKLKQLISEEEHVNEEMKQVVEAIEKLD
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein BCAH187_A3894.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: CAPA_STAAW
Sequence: MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNKISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF
What is the function of this protein?
Required for the biosynthesis of type 1 capsular polysaccharide.
What are the official names of this protein?
Capsular polysaccharide biosynthesis protein CapA.
What is the protein family that this protein belongs to?
Belongs to the CpsC/CapA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERA_GEOUR
Sequence: MTEKQFRSGFVSIIGRPNVGKSTLLNRILGDKIVITSDKPQTTRNRIQGIHNLPGCQMVFIDTPGIHRAKSKLNKYMVDVALSSIKEVDVILFLVEADAKPANQEGMILELLANADAPVLLVINKIDLVAKEALLERIAAYAALYPFREIVPVSALSGDGVERLVEVVHGFIPAGPPYFPDDILTDLPERFIVAEMIREKIFRLTHDEVPYSVAVVVESFKERADGLVSIAAAINVERESQKGIVIGKKGEMLKRIGMQARREIEELLDTKVFLELFVRVSKEWSENTRMLKEFGYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: SAHH_SULAC
Sequence: MDYRVKDLSLAEQGRKQIEWAELHMPALMEIRKRFNAEKPLDGIRIGAVLHVTKETAVLVETLKAGGAEIALAGSNPLSTQDDVAAGLAKNGIHVYAWRGETEKDYYDNIREILKYEPHVIMDDGGDLHAYVHENNLTSKIVGGTEETTTGVIRLKAMEEEKVLKYPVIAVNNAFTKYLFDNRIGTGQSTIDGILRATNILIAGKVAVVIGYGWVGRGIASRFKGMGARVIVVESSPFRALEALMDGFDVMTMNRASEIGDIFVTATGNLNVVSRDHILRMKDGAVLANSGHFNVEIDVKGLKEISVETREVRQNLEEYKLRNGKRIYLLADGRLVNLVAAEGHPSEVMDLSFCNQALSVEHLIKNKGKLENKVYNVPIEIDEQVARLKLKALGIEIEELTIEQKEYIKQWKYGT
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_WOLTR
Sequence: MKHKIKKRKLSRCTEHRLSMLKNLSISLINHEQIITTLPKAKELRPYVEKFITIAKNKNTLHGRRLLLSRLHNNKLVVDKLLNVLASRYQGCKGGYSRVMKFSTRKGDCASMAVIELVNRDVTAKGKVCDKNKEKNEVATKS
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL21_MANSM
Sequence: MYAVFQSGGKQHRVSEGQVVRLEKLEKATGETVEFDSVLMVVNGEDVKIGAPVVTGAKVVAEVVAQGRGDKIKIVKFRRRKHSRKQQGHRQWFTEVKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CHT_NEUCR
Sequence: MVLTKYKAAAVTSEPCWFDLEGGVRKTIDFINEAGQAGCKLVAFPEVWIPGYPYWMWKVTYQQSLPMLKKYRENAMAVDSDEFRRIRRAARDNQIYVSLGFAEIDHATLYLAQALIDPTGEVINHRRKIKPTHVEKLVYGDGAGDTFMSVTPTELGRLGQLNCWENMNPFLKSLNVSMGEQIHIAAWPIYPGKETLKYPDPATNVADPASDLVTPAYAIETGTWTLAPFQRLSVEGLKKNTPEGVEPETDPSTYNGHARIYRPDGSLVVRPDKDFDGLLFVDIDLNECHLTKALADFAGHYMRPDLIRLLVDTSRKELVTEVDRNGGIVQYSTRERLGLNTPLENDKEGKK
What is the function of this protein?
Catalyzes the hydration of cyanide to formamide.  Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants.
What are the official names of this protein?
Cyanide hydratase, CHT, Cyanide-degrading nitrilase, Formamide hydrolyase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: TREC_BACSU
Sequence: MKTEQTPWWKKAVVYQIYPKSFNDTTGNGVGDLNGIIEKLDYLKTLQVDVLWLTPIYDSPQHDNGYDIRDYYSIYPEYGTMEDFERLVSEAHKRDLKVVMDLVVNHTSTEHKWFREAISSIDSPYRDFYIWKKPQENGSVPTNWESKFGGSAWELDEASGQYYLHLFDVTQADLNWENEEVRKHVYDMMHFWFEKGIDGFRLDVINLISKDQRFPNAEEGDGRSFYTDGPRVHEFLHEMNEKVFSHYDSMTVGEMSSTTVDHCIRYTNPDNKELDMTFSFHHLKVDYPNGEKWALAPFDFLKLKEILSDWQTGMHAGGGWNALFWCNHDQPRVVSRYGDDGAYRVKSAKMLATAIHMMQGTPYIYQGEELGMTNPKFTDISSYRDVESLNMYHAFKEKGMADQDITAILQAKSRDNSRTPVQWDATENGGFTTGTPWIPVAGNYREINAEAALRDQNSVFYHYQKLIQIRKMYDIVTEGTYEIIAKDDPNIFAYLRHGSNEKLLVINNFYGTEAAFTLPDSLAPDEWKAEVLLTNDEAREGLQNMTLRPYESIVYRLTKPC
What is the function of this protein?
Hydrolyzes trehalose-6-phosphate to glucose and glucose 6-phosphate.  Can also very effectively hydrolyze p-nitrophenyl-alpha-D-glucopyranoside, but not lactose, maltose, sucrose or sucrose-6-phosphate.  Trehalose is also hydrolyzed, but to a much smaller extent than trehalose-6-phosphate.
What are the official names of this protein?
Trehalose-6-phosphate hydrolase, Alpha,alpha-phosphotrehalase, Phospho-alpha-(1-1)-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_PSEAB
Sequence: MTASSPSLSPTLELACELIRRPSVTPLDADCQALMMRRLEAAGFALEPMRIEEVDNFWARRGGDGPVLCFAGHTDVVPTGPLQAWQHQPFDALIDDQGMLCGRGAADMKGSLASMIVAVERFVADHPKHKGAIAFLITSDEEGPAHHGTKAVVERLAARGERLDWCIVGEPSSTSLVGDVVKNGRRGSLGAKLTIRGVQGHVAYPHLAKNPIHLAAPALAELAAEHWDDGNAFFPPTSFQVSNLNSGTGATNVIPGELTALFNFRFSTESTVEGLQKRVEAILDKHGLDWHVEWALSGLPFLTEPGELLDAVAASIRAVTGREARPSTSGGTSDGRFIATMGTQVVELGPVNATIHQVNERVLASDLELLTEIYYQTLVRLLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: LDH_DESVV
Sequence: MNRIAVIGVGNVGMAFAYAAAIKRLANDIVLIDANAARAEGESMDLADAMALVGPVQIRSGGYEQCEGARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVDVLTHVARTVTGVAPGRVIGSGTVLDSARFRGHVAEILGVDVRGVHAHIVGEHGDSEVALWSRANVSGIPVAEMCARRGIAYDAAFREKALGHVRHAAYEIIGRKGATGYGIGMSLCRIVEAILHDEHSVLTVSCPVAGHYGLGDVSLSLPCVIGSDGIEEVLDAPIAEDEQAALAASARVLGEHLAAL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCMO_STRGA
Sequence: MTPHTHVRGPGDILQLTMAFYGSRALISAVELDLFTLLAGKPLPLGELCERAGIHPRGARDFLDALVALGLLEREGEDTYRNSPAADRHLDRRKPGYVGGYARLADTKLFPVWARLTEALRTGEKQVPSQGGFFGGYADPEAARGFLGAMDAVNGGVGHSLAGALDWTEYSSFVDLGGARGNLAAHLHRAHPHLRATCFDLPEMEPFFQEHMKSLETTDQVRFAGGDFFTDPLPRADVFIVGHILHYFGLRQREALIARIHQALTPGGAVLVYDRMIDDDRRSAALSLLGSLNMLLTSDEGREYTPAECVRWLSDAGFTDVRTTAVSGPDTLAIGRKPR
What are the official names of this protein?
Tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: AMP2_CENMR
Sequence: DLPECCSATELELDSGKQTS
What is the function of this protein?
May have antimicrobial activity.
What are the official names of this protein?
Putative antimicrobial protein 2.
Protein: LPXK_MAGSA
Sequence: MRAPDFWRKDNAVSRLLAPLGAIYGWAVRRNLERAEEYRPAVPVICVGNIVVGGAGKTPVGIALARRLIAAGVKPHFLTRGYGGTEVGPRAVDLDRHDFARVGDEALLLAREAPTWVSRWRPDGAVAATEMGAEVIIMDDGFQNGSIAKDLSLVVVDGSYGFGNGRTMPAGPCREPPDQGLARADAMVVIGKDRRGLAELARAHGIPLLAARLVPGPEGADLKGRKVVAFAGIGRPEKFFASLKQCGARLTADHSFPDHHPFTRADIEALLAEAEANEALLITTAKDRVRLPADLRARVAVLSVSLDWDAPSLLTPLFDRIGVRA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.