PharMolix/UniProtQA huggingface dataset:
Protein: GCS2_SHIDS
Sequence: MPLSDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNEITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYPIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPYTGDRRPLTEDTLRLLEKIAPSAHKIAASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: TRPF_STRP7
Sequence: MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAELAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQVDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQHFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: MTGA_NEIGO
Sequence: MFRIVKWLIALPVGIFIFFNAYVYGNIITYRAVAPHRTAFMSMRMKQFEQEGRDVALDYRWVPYNRISTNLKKALIASEDVRFAGHGGFDWDGIQNAIRRNRNSGEVKAGGSTISQQLAKNLFLNESRNYLRKGEEAAITAMMEAVTDKNRIFELYLNSIEWHYGVFGAEAASRYFYKKPAADLTKQQAAKLTALVPAPLYYADHPKSKRLRNKTNIVLRRMGSAELPESDTD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Monofunctional biosynthetic peptidoglycan transglycosylase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: KGUA_STRPQ
Sequence: MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALMREYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDL_SHIF8
Sequence: MEYRSLTLDDFLSRFQLLRPQINREPLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: COX14_RAT
Sequence: MPSAKQLADIGYKTFSASMMLLTVYGGYLCSVRAYHYLQLRSARRQAAEEQKTSGVL
What is the function of this protein?
Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.  Requires for coordination of the early steps of cytochrome c oxidase assembly with the synthesis of MT-CO1.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX14.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: EKI2_MOUSE
Sequence: MAVPPSAPVPCSPFYLRRQEPCPQCSWSMEEKAVASAGCWEPPGPPRAAVPCFSVTVEQDDILPGALRLIRELRPHWKPEQVRTKRFKDGITNKLLACYVEEDMRDCVLVRVYGERTELLVDRENEVRNFQLLRAHGCAPKLYCTFQNGLCYEYVQGVALGPEHIREPQLFRLIALEMAKIHTIHANGSLPKPTLWHKMHRYFTLVKDEISPSLSADVPKVEVLEQELAWLKEHLSQLDSPVVFCHNDLLCKNIIYDSDKGRVCFIDYEYAGYNYQAFDIGNHFNEFAGVNVVDYSRYPARETQVQWLRYYLEAQKGTAASPREVERLYAQVNKFALASHFFWALWALIQNQYSTISFDFLRYAVIRFNQYFKVKPQVSALEMPK
What is the function of this protein?
Highly specific for ethanolamine phosphorylation.  Does not have choline kinase activity.
What are the official names of this protein?
Ethanolamine kinase 2, EKI 2, Ethanolamine kinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the choline/ethanolamine kinase family.
Protein: CFA95_HUMAN
Sequence: MDSLDRSCQDWCDRKQHWLEIGPPDLVERKGSLTLRSHHKKYSKPVLVYSWHRDREAFPKGYDIEGPEKVKKLCNSTYRRLGTDESPIWTSETHEKLSQMCLNTEWVEMKSKALLNEETVSSGIIERVTGLPATGFGAVFPRHPPDWSKMCALTTYSEDYVPPYDYQPHAYPCQDDYSIVHRKCRSQFTDLNGSKRFGINTWHDESGIYANSDVKQKLYPLTSGPIVPI
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Cilia- and flagella-associated protein 95.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell membrane; Single-pass membrane protein. Cytoplasm.
Protein: CLAF_PASFU
Sequence: MDDKGGYRQINSAFNACAFDDILGSQMAQLPELPDVEQLTPRVLRILGQNPGKFTFQGTNTYVIGTGRQRLIIDTGGGEADWASLINDTLKARGITIARVLLTHWHGDHTGGVADLIRLYPDLEHHIYKNQPDRGQQNIYHAQTFDVEGATVRALHTPGHSEDHMCFILEEEGEPRAMFTGDTILGHGTSTMEDLSSFMDSLQNITDQQCEVGYSAHGAVIENLPLKMVQELRHKTRREAQVLTALASYASRGQRSLTTSELVAEIYGQSLNAETRAFALEPFIDQVLRKLAGDGKVGFEVRAGQRKWFIMDMMQGSIRPARSGSAREILVAA
What is the function of this protein?
Atrochrysone carboxyl ACP thioesterase; part of the gene cluster that mediates the biosynthesis of the bianthraquinone cladofulvin, a conidial pigment not required for virulence but that plays a role in fitness and resistance to environmental stresses including UV light and low-temperature stress (PubMed:24465762, PubMed:27274078).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) claG.  The atrochrysone carboxyl ACP thioesterase claF then breaks the thioester bond and releases the atrochrysone carboxylic acid from claG (PubMed:27274078).  This compound is decarboxylated by claH to yield emodin, which is further converted to chrysophanol hydroquinone by the reductase claC and the dehydratase claB (PubMed:27274078).  The cytochrome P450 monooxygenase claM then catalyzes the dimerization of nataloe-emodin to cladofulvin (PubMed:27274078).
What are the official names of this protein?
Atrochrysone carboxyl ACP thioesterase, ACTE, Cladofulvin biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: RL7_MYCMS
Sequence: MPITKDEIIKALEEMKLNELNELVKAIEDHFGVVASVGVAAAAPAEATNAAPTEVSVVMTSVGQQKVAVIKVVKELTGVGLMDAKKIVDGTMPVTIKEHVKPEEAEEMKAKLVEAGASIDLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CASK_HUMAN
Sequence: MKSFLLVVNALALTLPFLAVEVQNQKQPACHENDERPFYQKTAPYVPMYYVPNSYPYYGTNLYQRRPAIAINNPYVPRTYYANPAVVRPHAQIPQRQYLPNSHPPTVVRRPNLHPSFIAIPPKKIQDKIIIPTINTIATVEPTPAPATEPTVDSVVTPEAFSESIITSTPETTTVAVTPPTA
What is the function of this protein?
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: POPD3_HUMAN
Sequence: MERNSSLWKNLIDEHPVCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLCSAVWAWVDVCAADIFSWNFVLFVICFMQFVHIAYQVRSITFAREFQVLYSSLFQPLGISLPVFRTIALSSEVVTLEKEHCYAMQGKTSIDKLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPTEEGIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRYHYDIRLPNFYQMSTPEIRRSPLTQHFQNSRRYCDK
What is the function of this protein?
May play a role in the maintenance of heart function mediated, at least in part, through cAMP-binding.  May play a role in the regulation of KCNK2/TREK-1-mediated current amplitude (PubMed:31610034).
What are the official names of this protein?
Popeye domain-containing protein 3, Popeye protein 3.
What is the protein family that this protein belongs to?
Belongs to the popeye family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RAPZ_YERP3
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPQLASTLADRNISAAVSIDVRNMPESPEVFEHAMTQLPDSFSPQLLFLDADRNTLIRRYSDTRRLHPLSAKNLSLESAIDEESDLLEPLRSRADLIIDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVISFLDRHTEVHNFIYQTRSYLEQWLPMLETNNRSYLTVAIGCTGGKHRSVYVAEQLADYFRARGKNVQSRHRTLEKRKQ
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: AGAL_STRBB
Sequence: MARSVRRTTLALLLSAVLAMTLFVTAPAHAQDSTWTVSGPSARSGPQARLQLDATTGALTLQVSRGGRTVLEPSPLGIRTEGADLSRGLRLSGRERRVVAERYRTAVGKQRSRDVRMTETRFRFRGDGGARFDLVVRVSDDGVAYRYVLPKGSGDVLGETSAFTLPTDATAWLGAYRRDNENLFNQYPAATAPTGEYMAQALFETRGTYALIAESDLSGRYSAARLIHEAGLPTYRIGLWDERVTSDGALSTPWRALVVGDLATVTESTFTDDLAPASRVADTSWIRPGPALWTWLAGGKPAGQSLSMQKGYVDYAAQRGWPYVVVDAGWYFDPDQWDVTDPDWQTNSWIPELVTYARERGVGIQVWIHHRDLDTAEEREQWLPTLERWGVKGVKIDFMDSESQDTLRWYDEILPATAAHHLLVNFHGSTIPKGIQRTWPHVMTMEGVNGEEKRVNTAQHLTTLPFTRNVIGSMDFTPGAFHRPQRPNAASDAGELGLSVLYESGIQNLAGTPESYDARPLARGFLEQLPAAWDRTRLLAGRPGESAVLARASGGRWFIGGTFAGAAHTAEVPLRLGSGTWLVDLVLDGPDGLVREPRVVRGGDTLSVPVVADGGFAAIACHWRPGRTSCDRTAA
What are the official names of this protein?
Probable retaining alpha-galactosidase, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 97 family.
Protein: POL_BIV29
Sequence: MKRRELEKKLRKVRVTPQQDKYYTIGNLQWAIRMINLMGIKCVCDEECSAAEVALIITQFSALDLENSPIRGKEEVAIKNTLKVFWSLLAGYKPESTETALGYWEAFTYREREARADKEGEIKSIYPSLTQNTQNKKQTSNQTNTQSLPAITTQDGTPRFDPDLMKQLKIWSDATERNGVDLHAVNILGVITANLVQEEIKLLLNSTPKWRLDVQLIESKVREKENAHRTWKQHHPEAPKTDEIIGKGLSSAEQATLISVECRETFRQWVLQAAMEVAQAKHATPGPINIHQGPKEPYTDFINRLVAALEGMAAPETTKEYLLQHLSIDHANEDCQSILRPLGPNTPMEKKLEACRVVGSQKSKMQFLVAAMKEMGIQSPIPAVLPHTPEAYASQTSGPEDGRRCYGCGKTGHLKRNCKQQKCYHCGKPGHQARNCRSKNREVLLCPLWAEEPTTEQFSPEQHEFCDPICTPSYIRLDKQPFIKVFIGGRWVKGLVDTGADEVVLKNIHWDRIKGYPGTPIKQIGVNGVNVAKRKTHVEWRFKDKTGIIDVLFSDTPVNLFGRSLLRSIVTCFTLLVHTEKIEPLPVKVRGPGPKVPQWPLTKEKYQALKEIVKDLLAEGKISEAAWDNPYNTPVFVIKKKGTGRWRMLMDFRELNKITVKGQEFSTGLPYPPGIKECEHLTAIDIKDAYFTIPLHEDFRPFTAFSVVPVNREGPIERFQWNVLPQGWVCSPAIYQTTTQKIIENIKKSHPDVMLYQYMDDLLIGSNRDDHKQIVQEIRDKLGSYGFKTPDEKVQEERVKWIGFELTPKKWRFQPRQLKIKNPLTVNELQQLVGNCVWVQPEVKIPLYPLTDLLRDKTNLQEKIQLTPEAIKCVEEFNLKLKDPEWKDRIREGAELVIKIQMVPRGIVFDLLQDGNPIWGGVKGLNYDHSNKIKKILRTMNELNRTVVIMTGREASFLLPGSSEDWEAALQKEESLTQIFPVKFYRHSCRWTSICGPVRENLTTYYTDGGKKGKTAAAVYWCEGRTKSKVFPGTNQQAELKAICMALLDGPPKMNIITDSRYAYEGMREEPETWAREGIWLEIAKILPFKQYVGVGWVPAHKGIGGNTEADEGVKKALEQMAPCSPPEAILLKPGEKQNLETGIYMQGLRPQSFLPRADLPVAITGTMVDSELQLQLLNIGTEHIRIQKDEVFMTCFLENIPSATEDHERWHTSPDILVRQFHLPKRIAKEIVARCQECKRTTTSPVRGTNPRGRFLWQMDNTHWNKTIIWVAVETNSGLVEAQVIPEETALQVALCILQLIQRYTVLHLHSDNGPCFTAHRIENLCKYLGITKTTGIPYNPQSQGVVERAHRDLKDRLAAYQGDCETVEAALSLALVSLNKKRGGIGGHTPYEIYLESEHTKYQDQLEQQFSKQKIEKWCYVRNRRKEWKGPYKVLWDGDGAAVIEEEGKTALYPHRHMRFIPPPDSDIQDGSS
What is the function of this protein?
Integrase catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.  This enzyme activity takes place after virion entry into a cell and reverse transcription of the RNA genome in dsDNA (By similarity).
What are the official names of this protein?
Gag-Pol polyprotein, Pr170Gag-Pol.
What are the subcellular locations of this protein?
[Matrix protein p16]: Virion. SUBCELLULAR LOCATION: [Capsid protein p26]: Virion.
Protein: SCX4_LEIQU
Sequence: GVRDAYIADDKNCVYTCGSNSYCNTECTKNGAESGYCQWLGKYGNACWCIKLPDKVPIRIPGKCR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Alpha-toxin Lqq4, Lqq IV, LqqIV, Toxin IV.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MEND_SHESW
Sequence: MRTENTATLNLIWGALILEELARIGVQHVCMAPGSRSTPLTLAAAQQTKLKRHLHFDERGLGFMALGLAKASRAPVAIITTSGTAVANLYPAIVEAWLTHVPLIVLSGDRPPELLDCGANQAIVQPGIFAHYAKQINLPTPDAHIAPQALLTTIDEAVANQTRPVHINCMYREPLYPSELGTPILDTESPYLKPLQTWLQLSRPYTQYGKYKQVSNPSDDAIMRFVHGKGVIVAGTLTPEQDPQQLIALSQKIGWPLLTDAQSQLRQHPAAIGNIDQLLQHPKARNLLQEADRVLVFGGRLLSKRLISYLAEQHWHSYWQVLPEQNRLDPSHNAKHVWHANAAQFTALNWYRSSSANWANTLITYNDELHNLFVRNIDHGEFGEAQVVRAIANTRPLEQQLFIGNSLPVRLYDMYAPVSCCTATTYTNRGASGIDGLLATACGLAAHEGKPTSLIIGDLSQLHDLNSLAIAKSLASPLVIVILNNDGGNIFNLLPVPNEQVRNDYYRLSHGLEFGYAAAMFNLPYNQVDNLADFQDSYNEALDFQGASIIEVNVSQTQASDQIAELNLWVKQS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: VL1_OVPVD
Sequence: MAFWQPGQALYLPPTPVTKVLCSEQYINVRDIFYHGETERMLTSGSILSLEVTQKHTTVPKVSPNQYRVFRVALPDPNQFALPDKALHNPSKERLVWAVVGVQVSRGQPLGGEVRGHSYFNTFLDAENVSKKVTAQGTDDRKQAGMDTKQQQVLMLGCTPAIGEYWTKARPCVTDRPDAGSCPPIELKLSFIEDGDMMDIGFGAANFKELNATKSDLPLDIANSICLYPDYLKMTEEAAGNSMFFFARKEQVYVRHIWTPWGTDKELPPEAYYLKPPGEMELKMPSVFFASPSGSLVSTDGQLFNRPYWILRAQGMNNGVCWNNTLFVTVGDNTRGSTLTITVPNNDEPLTEYDTSKFNVYQRHVEEFKLAFILELCSVELTPETVSSLQGSMPSILENWEINLQPPTSSVLEDIYRFIDSPATKCADNVSPSKPEDPYSAHKFWEVNLKEKLSLDLDQFPLGRLVLQFDCRLDRLLPQKDHFTYPEKRYKRHMRITGTVRKVLLYICFSLNS
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: MOUB_ORNMO
Sequence: MMLVLTTLIFSFSASIAYAQSGCSVSDPLDALKAFKDGAGTFLLQKSTDPQARDCLKGTPNGNRDGNTLPVTMTYKDDSKWVSLNWMFTLEGANIVATLEGKRKQRGELVYDVQSHDCHITKLSSGVYQQWQSNGSADDKDIKCCDEKFKELTSGIDYTKPQEKGCETSAK
What is the function of this protein?
Tick salivary platelet aggregation inhibitor that plays an important part in the anti-hemostatic strategy of ticks.  Acts by scavenging thromboxane A2 (TXA2), a potent inducer of platelet aggregation and blood vessel constriction (PubMed:8449906, PubMed:18694828).  As a consequence, is a specific inhibitor of collagen-induced platelet aggregation (PubMed:8449907, PubMed:8449906).  In addition, it also acts as a potent inhibitor of TXA2-mediated vasoconstriction (PubMed:18694828).  Has also been found to bind leukotriene B4 (LTB4) (which also derives from arachidonic acid, as TXA2) with affinities in the nanomolar range (PubMed:18694828).  It does not interact with complement protein C5 (PubMed:18694828).
What are the official names of this protein?
Moubatin, Lipocalin, Platelet aggregation inhibitor, PAI.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF1_BURPS
Sequence: MKTSMQSKLDQLTTRLAELNDLLSRENVTADLDQYRKLTREHAEIGPVVEHYAQWRQARADELAAQELLADASMRDFAEDELRGARDRMGRLAAELQTMLLPKDPNDERNIFVEIRAGTGGDESALFAGDLLRMYLRYAERQRWQVEMMSESPSDLGGYKEVIVRIAGYGAYSRLKFESGGHRVQRVPATETQGRIHTSACTVAVMPEADEIGEVEINPADLRIDTFRASGAGGQHINKTDSAVRVTHIPTGIVVECQDDRSQHKNKDRALKVLAARIKDKQYHEQHAKEAATRKSLIGSGDRSERIRTYNFPQGRMTDHRINLTLYKLEQIMDGDLDELIAALVSEHQAELLASLGDAE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_MANES
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPDYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYGLEPVPGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRVPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVCARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNDIIREASKWSPELAAACEVWKEIKFEFAAVDTLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: INS1_CONMR
Sequence: MTTSSYFLLVALGLLLYVCQSSFGGEHVCGSNQPNHPNGKCGSKMADYLEEQCEEEEAAHGGTNDARATTGRALSLSKRRGFLSMLKRRGKRNEASPLQRAGRGIVCECCKNHCTDEEFTEYCPHVTESG
What is the function of this protein?
This venom insulin facilitates prey capture by rapidly inducing hypoglycemic shock.  Intraperitoneal injection of this peptide into zebrafish lowers blood glucose with the same potency than human insulin.  In vivo, when applied to water, this peptide reduces overall locomotor activity of zebrafish larvae, observed as a significant decrease in the percentage of time spent swimming and movement frequency.
What are the official names of this protein?
Con-Ins M1, Insulin 1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSMD4_HUMAN
Sequence: MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLITLANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGPSLADALISSPILAGEGGAMLGLGASDFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAGIATTGTEDSDDALLKMTISQQEFGRTGLPDLSSMTEEEQIAYAMQMSLQGAEFGQAESADIDASSAMDTSEPAKEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAMGSLASQATKDGKKDKKEEDKK
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction.  Displays a preferred selectivity for longer polyubiquitin chains.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 4, 26S proteasome regulatory subunit RPN10, 26S proteasome regulatory subunit S5A, Antisecretory factor 1, AF, ASF, Multiubiquitin chain-binding protein.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5A family.
Protein: DVL1_HUMAN
Sequence: MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVKEEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSFHPNVASSRDGMDNETGTESMVSHRRERARRRNREEAARTNGHPRGDRRRDVGLPPDSASTALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFSSITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPIDPAAWLSHTAALTGALPRYGTSPCSSAVTRTSSSSLTSSVPGAPQLEEAPLTVKSDMSAVVRVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGFLRHTVNKITFSEQCYYVFGDLCSNLATLNLNSGSSGTSDQDTLAPLPHPAAPWPLGQGYPYQYPGPPPCFPPAYQDPGFSYGSGSTGSQQSEGSKSSGSTRSSRRAPGREKERRAAGAGGSGSESDHTAPSGVGSSWRERPAGQLSRGSSPRSQASATAPGLPPPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVDIM
What is the function of this protein?
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors.  Plays a role both in canonical and non-canonical Wnt signaling.  Plays a role in the signal transduction pathways mediated by multiple Wnt genes.  Required for LEF1 activation upon WNT1 and WNT3A signaling.  DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
What are the official names of this protein?
Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1.
What is the protein family that this protein belongs to?
Belongs to the DSH family.
Protein: SPX_STRA5
Sequence: MITLFLSPSCTSCRKARAWLSKHEVAFEEHNIITSPLNKEELLQILSFTENGTEDIISTRSKVFQKLAIDVDELSTSSLMELISENPSLLRRPIILDKKRMQIGFNEDEIRAFLPRDYRKQELKQATIRAEIEGKHD
What is the function of this protein?
Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes.  Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP).  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
What are the official names of this protein?
Global transcriptional regulator Spx.
What is the protein family that this protein belongs to?
Belongs to the ArsC family. Spx subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_THEAB
Sequence: MGRSTKKGPYVDPKLLKKIRQLNEAGEKKIIKTWSRASMIVPEMVGHTIAVYNGLKHIPVYITENMVGHRLGEFSFTRRFGGHADKSASKGQVKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.