PharMolix/UniProtQA huggingface dataset:
Protein: DAT1B_SOYBN
Sequence: MAISDEPESVATALNHSSLRRRPSATSTAGLFNSPETTTDSSGDDLAKDSGSDDSINSDDAAVNSQQQNEKQDTDFSVLKFAYRPSVPAHRKVKESPLSSDTIFRQSHAGLFNLCIVVLVAVNSRLIIENLMKYGWLIKSGFWFSSKSLRDWPLFMCCLSLVVFPFAAFIVEKLAQRKCIPEPVVVVLHIIITSTSLFYPVLVILRCDSAFVSGVTLMLFSCVVWLKLVSYAHTNYDMRALTKLVEKGEALLDTLNMDYPYNVSFKSLAYFLVAPTLCYQPSYPRTPYIRKGWLFRQLVKLIIFTGVMGFIIEQYINPIVQNSQHPLKGNLLYATERVLKLSVPNLYVWLCMFYCFFHLWLNILAELLRFGDREFYKDWWNAKTVEDYWRMWNMPVHKWMIRHLYFPCLRHGLPKAAALLIAFLVSALFHELCIAVPCHIFKLWAFGGIMFQVPLVLITNYLQNKFRNSMVGNMIFWFIFSILGQPMCVLLYYHDLMNRKGKLD
What is the function of this protein?
Major contributors to triacylglycerol (TAG) synthesis and oil accumulation in developing seeds.  Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA.  Has a marked preference for oleoyl-CoA and sn-1,2-dioleoylglycerol over vernoloyl-CoA and sn-1,2-divernoloylglycerol.
What are the official names of this protein?
Diacylglycerol O-acyltransferase 1B, GmDGAT1B.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y2662_BACCN
Sequence: MTLQTFQSADFAVFSVDGLERRMNAIKTHIQPKLETLGERFSHYLSDQTGEPFFYHVAKHARRKVNPPNDTWVAFSTNKRGYKMLPHFQIGLWGTHAFIYFGLIYECPQKEVAAHALLEHLNDLKTNIPNDFVWSIDHTKPDVLPHNTLEAKDLQKIIERLATVKKAELLVGIHIAPEEFSSMTNEQFQTKIESTIHSLLPLYNICNR
What are the official names of this protein?
UPF0637 protein Bcer98_2662.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: RL2_VIBC1
Sequence: MAIVKCKPTSPGRRHVVKVVNADLHKGKPYAPLLEKNSKNGGRNNNGRITVRHIGGGHKHHYRVVDFKRTKDGIPATVERLEYDPNRSANIALVLYKDGERRYILAPKGVNAGDVIQSGVDAPIKAGNTLPMRNIPVGSTVHNVELKPGKGGQLARSAGAYAQIVARDGAYVTIRLRSGEMRKVLSEGRATIGEVGNSEHMLRELGKAGASRWRGVRPTVRGVVMNPVDHPHGGGEGRTSGGRHPVSPWGMPTKGFKTRKNKRTDKYIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y1808_MYCLB
Sequence: MTLPLLGPMSLSGFEHSWFFLFIFIVFGLAAFYVMMQVARQRRMLRFANMELLESVAPNRPVQWRHVPAILLMLALLLFTIAMAGPTNDVRIPRNRAVVMLVIDVSQSMRATDVEPNRMAAAQEAAKQFAGELTPGINLGLIAYAGTATVLVSPTTNRYATKNALDKLQFADRTATGEAIFTALQAIATVGAVIGGGEMPPPARIVLFSDGKETMPTNPDNPKGAYTAARTAKDQGVPISTISFGTVYGFVEINGQRQPVPVDDETMKKVAQLSGGNSYNAATLAELKAVYASLQQQIGYETIKGDASAGWLRLGVLVLALAALTALLINRRLPT
What are the official names of this protein?
UPF0353 protein MLBr01808.
What is the protein family that this protein belongs to?
Belongs to the UPF0353 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VM2I_SISTE
Sequence: EAGEECDCGSPANPCCDAATCKLRPGAQCADGLCCDQCRFMKKGTVCRVARGDWNDDTCTGQSADCPRNGLYG
What is the function of this protein?
Inhibits fibrinogen interaction with platelets.  Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen.
What are the official names of this protein?
Disintegrin tergeminin, Platelet aggregation activation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IF2_CLAMS
Sequence: MAKPRVHEIAAEIGVDSKTALAKLKEMGEFVKGPSSSIEPPVARKLKAALEAAGVTGQAAAPAAAASSAPRPGARSSAPKPGGRPTPGPQPTAAPEVEAPEASDVPVPAKPLTVAERQAQAEASRKAAAEEKAQAEKSAASATPEAPAVETPSAPRPDAGSTPAPSNGIPRPGIPRPAAPRPGNNPFASNQGMGTKPRPGNNPFASNQGMGQRPAAGAAGPRPAAPRPGSPRPGAPRPGGVGQGARPAGFGQRPAGAGRPGGAPGGAGRPGAPAAGGFQRPAGGFAGRPGGGGRGRGPGGGTAGAFGRGGGKSKSRKSKRTKRAEFELREAPSLGGVSVPRGDGNTVVRLRRGASISDFADKIDASPGNLVTVLFHLGEMATATESLDEATFEVLGTELGYKIQVVSPEDEDRELLEGFDIDLDQELEDEDDDVLEIRPPVVTVMGHVDHGKTRLLDAIRNANVIEGEAGGITQHIGAYQVWAPHEGYERAITFIDTPGHEAFTAMRTRGAQVTDIAILVVAADDGIMPQTVEALNHAQAANVPIVVAVNKVDKEGANPAKVRQQLTEYGLVAEEYGGDVMFVDVSALTGKGVEDLLEAVLLTADAGLDLRSNPNKDARGVAIEARLDKGRGAVATVLIQSGTLRVGDAIVAGTAYGRVRAMMDENGDAVHEAYPSRPVQVQGLSSVPGAGDTFLVTEEDRTARQIAEKREAVERNAQLAKARKRISLEDFTRALEEGKVESLNLIIKGDVSGAVEALEESLMKIEVDDSVQLRIIHRGVGAVTESDVNLATIDNAIIIGFNVRPDPKARARAAREGVDIRFYSVIYSALEEIESSLTGMLKPEFEEVQSGVAEIREVFRSSKFGNIAGVIVRSGTITRNAKARVIRDGVVVGDSLAIESLRRFKDDVSEVRTDFEAGIGLGKFNDIQIGDEIETIEMKEKPRG
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_XANOP
Sequence: MSQGKIVQIIGAVVDVEFPRNEVPKVYHALKVEGTEITLEVQQQLGDGVVRTIALGSTDGLKRNLLATNTERAISVPVGAGTLGRIMDVLGRPIDEAGDVQASDHWEIHRGAPSYEDQSSSTELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEYFRDEKDANGKGKDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKSGSITSIQAVYVPADDLTDPSPATTFAHLDSTVTLSRNIASLGIYPAVDPLDSTSRQMDPLVIGHEHYDTAQRVQQTLQKYKELKDIIAILGMDELSEEDKQSVSRARKIERFFSQPFHVAEVFTGSPGKYVSLKDTIRGFKAICDGEYDHLPEQAFYMVGSIEEAVEKANKMSAKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ZEA8_MAIZE
Sequence: MATKIFSLLMLLALSACVANATIFPQCSQAPIASLLPPYLPSMIASVCENPALQPYRLQQAIAASNIPLSPLLFQQSPALSLVQSLVQTIRAQQLQQLVLPLINQVALANLSPYSQQQQFLPFNQLSTLNPAAYLQQQLLPFSQLATAYSQQQQLLPFNQLAALNPAAYLQQQILLPFSQLAAANRASFLTQQQLLPFYQQFAANPATLLQLQQLLPFVQLALTDPAASYQQHIIGGALF
What is the function of this protein?
Zeins are major seed storage proteins.
What are the official names of this protein?
Zein-alpha 19C1, 19 kDa zein 19C1.
What is the protein family that this protein belongs to?
Belongs to the zein family.
Protein: RL32_CHRSD
Sequence: MAVQQNRKTRSKRGMRRSHDALSAPTLSQDKETGTTHRRHHVAPDGFYRGRKVVDV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RRF_BRUA1
Sequence: MSDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISVPESRMLSVSVWDKSMVGAVERAIRDSGLGLNPITDGMTLRIPLPELNEQRRKELVKIAHQYAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEKVQKLTDDTIAEMDKIVAVKEGEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_PSEA7
Sequence: MVPVIALVGRPNVGKSTLFNRLTKSRDAIVAEYAGLTRDRQYGEARWQGRTYIVIDTGGISGDEEGIDAKMAEQSLQAIEEADAVLFLVDSRAGMTAADQMIAEHLRKRNKRSFLIANKVDTIDPDLARAEFSPLGLGDALPIAAAHGRGINHMLQEALGIFPKDNAEEEGEGEPASEEVAEGEEPTRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEERVIVYDQAGTTRDSIYIPFERNEEKYTLIDTAGVRRRGKIFEAVEKFSVVKTLQAIQDANVVIFVMDAREGVVEHDLNLLGFVLETGRALVIALNKWDGMEAAERDYVKTELERRLLFVDFADIHFISALHGTGVGHLYKSVQESFRSAVTRWPTSRLTSILEDAVQVHQPPMVNGRRIKLRYAHLGGANPPLIVIHGNQVDAVPKAYTRYLEKTYRRVLKLVGTPIRIEYKGGENPYEGKKNSLTARQVNKKRRLMSHHKKAEKKKKDKRR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TED_HASHE
Sequence: KQCTSNMCSADCSPGCCIIDKLEWCTCDC
What are the official names of this protein?
Augerpeptide hheTx3.
What are the subcellular locations of this protein?
Secreted.
Protein: MDH_PYRIL
Sequence: MITIIGSGRVGTAAAVIMGLLKIDTKILLIDIIKGLPQGEALDMNHMSSILGLDVEYFGSNEYKDMEGSDLVIVTAGLPRKPGMTREQLLEANAKIVSEIGKEIKRYAPNSVVILTTNPLDAMTYVMWKSTGFPRERVIGFSGVLDAGRLAYYAAKKLGVSPASILPIVLGQHGESMFPVPSKSFIHGVPLSRLLTEEQLKEVVEETVKAGARITELRGFSSNWGPGAGLALMAEAVKRDTKRSLIASVVLQGEYDVRDVPVEVPVILGRSGVLKVLEIELSAEERQKFMQSVEAIRKLIASIPSNYLQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.  Exhibits higher specific activity for oxaloacetate reduction than for malate oxidation in vitro.  Has a strong preference for NAD.  Can use NADPH for oxaloacetate reduction, but activity decreases more than 90%.  No activity detected with NADP(+) and malate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: EIF3H_DROYA
Sequence: MANRANRHAARTEDSDNTINYVQCDGLAVMKMVKHCHEESSNMDLAQGALLGLVVDKCLEITNCFPFPKSGDETMDEEMYQLTVMRRLRRVNVDHLHVGWYQSSDVGNSLSLALLESQYHYQTSIEESVVVVYDTQKSSRGFLCLKAYRLTPQAIQMYKDGDFTPEAFRTLKVGYESLFAEIPIVIKNSPLTNIMMSELNELLPEDKGHNFLDLGTATVLENQMRSLIERVDELYQEAVRYNKYQQVVFKQDTEKHRALAKLAAENAVRTSKGEPTVAEEEVIKQFRPMTAPNRLTATITSGQINTHAQHIAQFCSQSLAKLFITESLQNAKEAKETK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h, Eukaryotic translation initiation factor 3 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPCH_SALDC
Sequence: MKNAFKDALKAGRPQIGLWLGLANSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIASYPSQPVVRPSWNDPVQIKQLLDVGAQTLLIPMVQNADEARNAVAATRYPPAGIRGVGSALARASRWNRIPDYLHQANDAMCVLVQIETREAMSNLASILDVDGIDGVFIGPADLSADMGFAGNPQHPEVQAAIENAIVQIRAAGKAPGILMANEALAKRYLELGALFVAVGVDTTLLARGAEALAARFGAEKNLSGASGVY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
What are the official names of this protein?
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, HHED aldolase, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase, HKHD aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: RL4_CAMLR
Sequence: MSKVTVLNDKFEKASELDLPAKYAEVNPHNLYLYVKSYLASLRANTAHTKGRSDVSGGGKKPWRQKGRGGARAGSTRTNVWVGGAVAFGPKNNRNYFQKVNKKQKRLALERALEDKAAKNALFSVDSLSIESGKTKDANAVIKKLGLKDVLIVKDLLDEKTLLAFRNLANCYVVDVNEVNAYLVSVFNAVIIEKAALESIVKEG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: TESA_ECOLI
Sequence: MMNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSASAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLRGFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVPLLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS
What is the function of this protein?
TesA is a multifunctional esterase that can act as a thioesterase, lysophospholipase and protease (PubMed:8098033, PubMed:8432696, PubMed:1864840, PubMed:4945109, PubMed:4554913, PubMed:238979, PubMed:791643, PubMed:8132479, PubMed:9070299, PubMed:10423542).  TesA functions as a thioesterase specific for fatty acyl thioesters of greater than ten carbons, with highest activity on palmitoyl-CoA, cis-vaccenoyl-CoA and palmitoleoyl-CoA (PubMed:8098033, PubMed:4554913, PubMed:8132479, PubMed:9070299, PubMed:10423542).  TesA also possesses an arylesterase activity towards short acyl-chain aromatic esters such as alpha-naphthyl acetate, alpha-naphthyl butyrate, benzyl acetate and phenyl acetate (PubMed:9070299).  Also able to hydrolyze short acyl-chain triacylglycerols such as triacetin and tributyrin, and p-nitrophenyl esters such as p-nitrophenyl hexanoate and p-nitrophenyl butyrate (PubMed:9070299).  The protease activity is mainly active on small peptides (PubMed:8432696, PubMed:9070299).  TesA is also able to hydrolyze p-nitrophenyl esters of N-substituted amino acids such as N-benzyloxycarbonyl-L-Phe-p-nitrophenyl ester (Z-L-Phe-ONp) and N-benzyloxycarbonyl-L-Tyr-p-nitrophenyl ester (Z-L-Tyr-ONp), however it is unable to hydrolyze N-acetyl-L-Phe ethyl ester and its Tyr analog (PubMed:8432696, PubMed:791643, PubMed:10423542).  TesA also hydrolyzes N-benzyloxycarbonyl-L-Phe beta-nitrophenyl ester (Cbz-Phe-ONap) and N-acetyl-DL-Phe-2-naphthyl ester (chymotrypsin-like specificity) (PubMed:8432696, PubMed:4945109).  Shows a slow proteolytic activity against denatured casein (PubMed:4945109).  The lysophospholipase activity of TesA is able to hydrolyze 1-palmitoyl-sn-glycero-3-phosphocholine, 1-acyl-sn-glycero-3-phosphoglycerol, 1- and 2-acyl-sn-glycero-3-phosphoethanolamine (PubMed:1864840, PubMed:238979, PubMed:10423542).
What are the official names of this protein?
Thioesterase 1/protease 1/lysophospholipase L1, TAP, Acyl-CoA thioesterase 1, TESA, Acyl-CoA thioesterase I, Arylesterase, Lysophospholipase L1, Oleoyl-[acyl-carrier-protein] hydrolase, Phospholipid degradation C, Pldc, Protease 1, Protease I, Thioesterase I/protease I, TEP-I.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL11_SHEHH
Sequence: MAKKVDGYIKLQVAAGAANPSPPVGPALGQKGVNIMEFCKAFNARTDKFEKGMPIPVVITVYSDRSFTFETKTPPASFLLLKAAGLKSGSGRPNTEKVGTIKRSAVQEIAETKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PUR9_ECOSM
Sequence: MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDTIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEIDANEGSLTLETRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTKRQPSEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: ECFA2_STAS1
Sequence: MTVKFSQVSYVYQKGTPFEHVALRDIETTFQQGKYYAVIGQTGSGKSTLIQHFNGLLKPSTGKLQIDDITITHKTKDKVLKQIRKRIGVVFQFPESQLFEDSVEREILFGPKNFNMPIDEVKARAYKLLIDFGFSRDILQQSPFQMSGGQMRKIAITSILAMDPDIVILDEPTAGLDPKSRDQIMKMIKKLQVEQNKTIILVTHEMNDVAKYVDEIKIMKQGQLVEECSPRKLFSDTNYVNQLHLDVPDVVKLQRDIEDKYQYYFNKIALTEDEFIDMYKEWQEDER
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PURL_STRCO
Sequence: MSRTPLDTVEHATATPDVELPWAELGLKKDEYERVVEILGRRPTGAELAMYSVMWSEHCSYKSSKVHLRQFGEKAPQSDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGEVVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGAGNKVILYGARTGGDGIGGASILASETFDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSGGMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLEICDKWDVIATVIGEVTDGDRLEIFWHGGKIVDVDPRTVAHDGPVYERPYARPDWQDALQADDANKLPRPGTSDELKAQVLKLVGSPNQASKQWITQQYDHFVQGNTVLAQPEDSGMIRVDEESGLGVAIATDGNGRYAKLDPYTGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAVRGLADGCLQLGTPVTGGNVSLYNQTGEAAIHPTPVVAVLGVIDDVARRTPVAFQEDGQLLYLLGDTREEFGGSAWSQVIHDHLGGLPPKVDLERERLLGEILISASRDGMIDSAHDLSDGGLVQAVVESALLGGKGARLVVPDGLDAFTFLFSESAGRAVVAVPRSEEVRFNDMCGARGLPVTRIGVVDGDAVEVQGEFTLPLTDLREAHESTIPGLLA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I80A2
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: GSA_MYCBP
Sequence: MGSTEQATSRVRGAARTSAQLFEAACSVIPGGVNSPVRAFTAVGGTPRFITEAHGCWLIDADGNRYVDLVCSWGPMILGHAHPAVVEAVAKAAARGLSFGAPTPAETQLAGEIIGRVAPVERIRLVNSGTEATMSAVRLARGFTGRAKIVKFSGCYHGHVDALLADAGSGVATLGLCDDPQRPASPRSQSSRGLPSSPGVTGAAAADTIVLPYNDIDAVQQTFARFGEQIAAVITEASPGNMGVVPPGPGFNAALRAITAEHGALLILDEVMTGFRVSRSGWYGIDPVPADLFAFGKVMSGGMPAAAFGGRAEVMQRLAPLGPVYQAGTLSGNPVAVAAGLATLRAADDAVYTALDANADRLAGLLSEALTDAVVPHQISRAGNMLSVFFGETPVTDFASARASQTWRYPAFFHAMLDAGVYPPCSAFEAWFVSAALDDAAFGRIANALPAAARAAAQERPA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_DICDI
Sequence: MGRMHSNGKGISGSSLPYNRKPHAWTKPTASEVCETVCKLAKRGYTPSKIGSSLRDSLGVAQVKNVTGSKILRILKVNGLAPTIPEDLYHLIKKAVTINKHLQRARKDYDGKFHLRLVESRIHRLTRPYRKNGTLAPNWKYESNNASTLVA
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ACH3_DROME
Sequence: MESSCKSWLLCSILVLVAFSLVSASEDEERLVRDLFRGYNKLIRPVQNMTQKVGVRFGLAFVQLINVNEKNQVMKSNVWLRLVWYDYQLQWDEADYGGIGVLRLPPDKVWKPDIVLFNNADGNYEVRYKSNVLIYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLALYNNKNFVDLSDYWKSGTWDIIEVPAYLNVYEGDSNHPTETDITFYIIIRRKTLFYTVNLILPTVLISFLCVLVFYLPAEAGEKVTLGISILLSLVVFLLLVSKILPPTSLVLPLIAKYLLFTFIMNTVSILVTVIIINWNFRGPRTHRMPMYIRSIFLHYLPAFLFMKRPRKTRLRWMMEMPGMSMPAHPHPSYGSPAELPKHISAIGGKQSKMEVMELSDLHHPNCKINRKVNSGGELGLGDGCRRESESSDSILLSPEASKATEAVEFIAEHLRNEDLYIQTREDWKYVAMVIDRLQLYIFFIVTTAGTVGILMDAPHIFEYVDQDRIIEIYRGK
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit beta-like 1, Nicotinic acetylcholine receptor beta 1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: GLYA_RALPJ
Sequence: MFERSRYTIDQIDPEIFAAIQKENQRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAVLKPGDTIMGMSLAEGGHLTHGMALNMSGKWFNVVSYGLNAQEDIDYDALEALAQEKKPKLIIAGASAFALRIDFERIGKIAKSIGAYFMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGVILMKAEHEKAINSAIFPGIQGGPLMHVIAGKAVAFKEALSPEFKAYQEQVVKNAAAMAETLMARGLRIVSGRTESHVMLVDLRAKKITGKEAEKVLGDAHITVNKNAIPNDPEKPFVTSGVRLGSPAMTTRGFKEAEAVKVAHLIADVLDNPHDEANIAAVRAKVAELTKQFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.