PharMolix/UniProtQA huggingface dataset:
Protein: ATPE_PSEAE
Sequence: MAITVHCDIVSAEAEIFSGLVEMVIAHGALGDLGIAPGHAPLITDLKPGPIRLVKQGGEQEVYYISGGFLEVQPNMVKVLADTVVRAGDLDEAAAQEALKAAEKALQGKGAEFDYSAAAARLAEAAAQLRTVQQLRKKFGG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RBL_ARIGL
Sequence: SVGFKAGVKDYRLTYYTPDYETKDTDILAAFRVTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEAVVGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPSYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREMTLGFVDLLRDDYIEKDRSRGIFFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIPEACNWSPELAAACE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NFIX_HUMAN
Sequence: MYSPYCLTQDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCSDGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQSWFL
What is the function of this protein?
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2.  These proteins are individually capable of activating transcription and replication.
What are the official names of this protein?
Nuclear factor 1 X-type, NF1-X, Nuclear factor 1/X, CCAAT-box-binding transcription factor, CTF, Nuclear factor I/X, NF-I/X, NFI-X, TGGCA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the CTF/NF-I family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y910_METJA
Sequence: MGAMRRMEAAKGAIISLLLDAYQKRNKIGMIAFRKDKAELILPFTSSVELGEKLLKDLPTGGKTPLADAFIKSYEVFDREIRKNPNIIPIMIVISDFKPNVAVKEDYVKEVFDACEKIAEKGINVILIDTEPQSFIKIGIGKEIANRFGFKYYKIEELSKDKILDICKSLEINF
What are the official names of this protein?
Uncharacterized protein MJ0910.
Protein: Y229_MYCBO
Sequence: MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRTLAADTAAMIGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAGVGYIGVEPDPDEMHAAGPAFTGRPGMFVRASGMALPLADDSVDICLSSNVAEHVPRPWQLGTEMLRVTKPGGLVVLSYTVWLGPFGGHEMGLSHYLGGARAAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPRWAWWLTSVPVLREFLVSNLVLVLTP
What are the official names of this protein?
Uncharacterized methyltransferase Mb0229c.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: KITH_BACCZ
Sequence: MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNGLKVKAVPVSASKDIFKHITEEMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLIDGEPAAFDDPIILVGASESYEPRCRHCHAVPTNKDK
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_MYCTA
Sequence: MAELAPDTVPLAGVVLAGGESRRMGRDKATLPLPGGTTTLVEHMVGILGQRCAPVFVMAAPGQPLPTLPVPVLRDELPGLGPLPATGRGLRAAAEAGVRLAFVCAVDMPYLTVELIEDLARRAVQTDAEVVLPWDGRNHYLAAVYRTDLADRVDTLVGAGERKMSALVDASDALRIVMADSRPLTNVNSAAGLHAPMQPGR
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_MYCSK
Sequence: MAKGKRTFQPNNRRRARVHGFRLRMRTRAGRAIVTGRRRKGRRSLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: NUBP2_DROSE
Sequence: MLDKVKNVIVVLSGKGGVGKSTVSTQLSLALRKNGFKVGLLDIDLCGPSVPYLLGLEGRDIFQCDEGWVPVYTDESQTLAVMSIGFLLKNREDPVIWRGPKKTMMIRQFLTDVRWDELDYLIIDTPPGTSDEHITVMECLKEVGCHGAIIVTTPQEVALDDVRKEITFCKKTGINILGIVENMSGFVCPHCTSCTNIFSSNGGVSLATYAQVPHLGTLPIDPRVGVLAGTTTSVLDELPDSTTAEVLTHLVEKLKTMLVS
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBK60_ARATH
Sequence: MRKTMVISDLPHEIESEILSRVPTKSLAKLHTTCKRWYALFRDPRFVKKNFGKSERRLMLHSNFGVYKITDDLHGILNSGDPSLEFTSKLSNLKISEDLTITKIFHCDGLILCSTKENTRLVVWNPCTGQTRWIKPSKRYRSDDSYCLGYVNSKSSYHNYKILRYCFYYNDQDACVSEFEIYDFSSESWRVLDDYCTREWGLFCHGMSLKGNTYFVAGEKETGFFMLYFDFKTERFERLPLPYQSFDSEDTAVLSIVGGEKLAVLHQNIQSFSNEMRIWVTNKIDEAKDLTWSNFFLAVDYDIFNLPSVNNVTSFLLDEENKVAVCCDRHIDDEDKTRIYIVGVDLYKEVYKERTKGAHFNWPLLISYLPSLVHIQEKYPKDKRKGNKRRLVKRIT
What are the official names of this protein?
Putative F-box/kelch-repeat protein At3g17540.
Protein: PSBA_HETPY
Sequence: MKNTFNTSNVFANAYSFWGYVIGFILSTSNRLYIGWFGILMFPLLVLATVAYIAAFIFAPPVDIDGIREPVAGALLYGNNIISGAVIPSSNAIGVHFYPVWEALGFDEWLYNGGTYQFVVLHFILGAGAYMGREWEFAFRLGMRPWIFVAFSAPLVAASAVFIVYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHILGVAAVFGGSLFSAMHGSLVTSSLVAETAGDLSLNVGYNFGQEDETYSISAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGVSTMAFNLNGLNFNQSIIDSSGHLINSWADIVNRADLGMEVMHERNAHNFPLDLA
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: URB2_YEAST
Sequence: MGDLTEELSIPDNAQDLSKLLRSTSTKPHQIAEIVSKFDKLETYFPKKEIFVLDLLIDRLNNGNLDDFKTSEHTWIIFTRLLDAINDPISIKKLLKKLKTVPVMIRTFFLWPKDKLLTRSVSFIKAFFAINDYLIVNFSVEESFQLLEHAINGLSSCPTTDFALSYLQDACNLTHVDNITTTDNKIATCYCKHMLLPSLRYFAQTKNSASSNQSFIRLSHFMGKFLLQPRIDYMKLNKKFVQENASEITDDMAYYYFATFVTFLSKDNFAQLEVIFTILGAKKPSLECRFLNLLSESKKTVSQEFLEALLLEMLASTDESGVLSLIPIILKLDIEVAIKHIFRLLELIQLENLNDPLFSSHIWDLIIQSHANARELSDFFAKINEYCSRKGPDSYFLINHPAYVKSITKQLFTLSSLQWKNLLQALLDQVNHDSTNRVPLYLIRICLEGLSEGASRATLDEVKPILSQVFTLESFNNSLQWDLKYHIMEVYDDIVPAEELEKIDYVLSSNIFDTTSADVEELFFYCFKLREYISFDLSDAKKKFMRHFEILDEERKSNLSYSVVSKFATLVNNNFTREQISSLIDSLLLNSTNLSSLLKNDDIFEETNITYALINKLASSYHQTFALEALIQIPIQCINKNVRVALINNLTCESFCLDSATRECLLHLLSSPTFKSNIETNFYELCEKTIMSPEMAISETGDEKKEIEDKISIFEKVWTNHLSQAKEPVSEKFLESGYDIVKQSMSLSNGDSKLIIAGFTIAKFLKPDNKHRDIQGMAISYAVKILENYSENFESETIPLFRISMSTLYKIITTGQGDISKHKSRILDIFSKIMLRYHSKKVYHAPEEQEMFLVHSLLTENKLEYIFAEYLNIEHTDKCDSALGFCLEESLKQGPDAFNRLLWNSAKSFSTISQPCAEKFVRVFIIMSKRIARDNNLGHHLFVIALLEAYTYCDIEKFGYKSYLLLFNAIKEFLVSKPWLFSQYCIEMLLPFCLKTLAFIVNHESTDEINEGFINIIEVIDHMLLVHRFKFSNRHHLFNSVLCQILEIIAIHDGTLCANSADAVARLITNYCEPYNVSNAQNGQKNNLSSKISLIKQSIRKNVLVVLTKYIQLSITTQFSLNIKKSLQPGIHAIFDILSQNELNQLNAFLDTPGKQYFKALYLQYKKVGKWRED
What is the function of this protein?
Required for 27S pre-rRNA processing.  Has an early role during 60S ribosomal subunit assembly.
What are the official names of this protein?
Nucleolar pre-ribosomal-associated protein 2, Unhealthy ribosome biogenesis protein 2.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYA_ACHLI
Sequence: MTSEQIRQTWLNFFKDKGHIIEPSASLIPVDDPTLLWINAGVAPLKKYFDGTETPKSKRITNIQKSIRTNDIDNVGKTARHHTFFEMMGNFSIGDYFKKEAIEFGFELLTSPKYFDIPLDKLYMTYYPTDVEAKNTWLKLGVKEDHLIPVEGNFWEIGAGPSGPDTEIFFDRGTSYDLRGPELIRDDIENERFIEIWNIVFSQYNADPKLKRSEYKELPNKNIDTGAGLERFACVLQGTKTNFETDLHYPVILKVESLSGVKYDGQMAFKVISDHIKTLVFAISDGANLSNEGRGYVLRRILRRAVKYGKSIGFDAPFLHLLVDTVVDMMSNFYTNLIETAVIVKKIILKEEEKFFSTILDGEKHLLQSIKDGKLSGEDAFKLYDTYGFPIELTIEYAEEHGITVDIKGFNEALEVQKSRSRDARKVTHSMKGQDEALLNFDVPSEFVGYDYLQTESKVIKVFDQGIVLDKTPFYANSGGQISDTGSINGLVVRDVIKLPHGQHLHLIETDAFTEGDEVLCIVNQDKRHHTMKNHTATHLLNQALKDTLGSHVKQQGSYNGDLKLTFDINHYETIKDEEILTVEKIVQQKIKEQIDVVTHVLPIDEAKKLGAAMQFGEKYGDIVRVVDVGSWSMEFCGGTHVKNTSDIKNFMITSVESIGSGTYRFEAITGQVLSQVKKIVQNLLDMIHQHIEKIKSLDENHNLKPLPELTGSYQDIINLRLYNQYISNESKVVEKQLEAKLIDQIILQADTFIPKTIEPTTYIYSDNLPQSSLKPLIDVLYDKIKADTVVLLNISEDKASYLVKSSVNEARNVINELNKVLDGRGGGKPDFAQGGTQALDKVQMFLKGKN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD2_RAT
Sequence: MRCKFLGSFFLLFSLSSKGADCRDSGTVWGALGHGINLNIPNFQMTDDIDEVRWERGSTLVAEFKRKMKPFLKSGAFEILANGDLKIKNLTRDDSGTYNVTVYSTNGTRILNKALDLRILEMVSKPMIYWECSNATLTCEVLEGTDVELKLYQGKEHLRSLRQKTMSYQWTNLRAPFKCKAVNRVSQESEMEVVNCPEKGLPLYLIVGVSAGGLLLVFFGALFIFCICKRKKRNRRRKGEELEIKASRMSTVERGPKPHSTQASAPASQNPVASQAPPPPGHHLQTPGHRPLPPSHRNREHQPKKRPPPSGTQVHQQKGPPLPRPRVQPKPPCGSGDVSLPPPN
What is the function of this protein?
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types.  CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
What are the official names of this protein?
T-cell surface antigen CD2, LFA-2, LFA-3 receptor, OX-34 antigen, T-cell surface antigen T11/Leu-5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MDTB_SALHS
Sequence: MQVLPPGSTGGPSRLFILRPVATTLLMAAILLAGIIGYRFLPVAALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPIYSKVNPADPPIMTLAVTSNAMPMTQVEDMVETRVAQKISQVSGVGLVTLAGGQRPAVRVKLNAQAVAALGLTSETVRTAITGANVNSAKGSLDGPERAVTLSANDQMQSADEYRRLIIAYQNGAPVRLGDVATVEQGAENSWLGAWANQAPAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSQQSLRKQNRFSRACERMFDRVIASYGRGLAKVLNHPWLTLSVAFATLLLSVMLWIVIPKGFFPVQDNGIIQGTLQAPQSSSYASMAQRQRQVAERILQDPAVQSLTTFVGVDGANPTLNSARLQINLKPLDARDDRVQQVISRLQTAVATIPGVALYLQPTQDLTIDTQVSRTQYQFTLQATTLDALSHWVPKLQNALQSLPQLSEVSSDWQDRGLAAWVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTASTPGLAALETIRLTSRDGGTVPLSAIARIEQRFAPLSINHLDQFPVTTFSFNVPEGYSLGDAVQAILDTEKTLALPADITTQFQGSTLAFQAALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALIIAGSELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIFQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIAMVGGLLVSQVLTLFTTPVIYLLFDRLSLYVKSRFPRHKEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INO80_MAGO7
Sequence: MEPSKFHSTVLARPPGMYDEDDDHRRRQRDILNPPAPSQTGPGSGGSSSAGGPRPPFSLRSPTQSEFHHQSSQHHYSASSAASGPQSTYNGANNGVPQSHSHSRSNSHSRHSSSSVLHSPYQQASTASRPAHALDLHRSPQTSGLQAPQRSPGLHAPSVYYSQESREHHPPPPKPIDKPASSGRSFYDPLTDTTTTSTSDRERRTSDAGSSWHNATTNAVSTPTHRDAYNSYSKPAANPSPYYGNGKYTSPSASIYPPRSPASHPQSVATAAAEPISPPTRPPRMATPNILNPTTTSSMAAMSQAESPAQKAAVPAATPSRAAELMSFSNILSSSEPAPKPRPRSPVLAETPNKQPEPEPEREPTKEPSKEPSKEPSKEPSKEPSPPPADMDETSDSPACPEKPAEVDAETEPDAEIHDDVDTVDGLEESEKPEPPIKREKSAKVEKAPRRPRVVEKEKKERVTKAPRKSAGAKGRASEVKAESTPKQSRRSSGKQEALSSSRVPAKRQANGLTKQKAQALEQEKAVVAEMEQLEEEALDESEARAELRAFKKRKLNRQKALETTDLSVATELLPSLKDEAINRHHRRHDFSAEMVLKLGVHVALGRLRFGDHNYDAALKEVREQELFAEKERKKDMQRKRRREKSMAVTIEQKEAALAKAHATEDKLERQKLLREAERANKKAQQTKLILQKGIKGPARNIMPMDVNLEGGSMATFSADSMEPGKGKGKGRAGNRPKKSKEQKQAEKEAAEAAQAALDAGQELPSKEENPKIRIKVNKGKLSKDKDRDVDVDTIDGDNTEIKDTEEPPPKKKGKVVEEVKDTLETRFQSKGYNQIYDQIWRDMARKDVSKVYRLATDSYYTKASNLKKTAILAAKEAKRWQLRTNKGMKDLQARGKRVMRDMMTFWKRNEREERDLRKAAERQELENARKEEADREAARQKRKLNFLISQTELYSHFIGKKIKTDEVERSTDRPEVAAEEQKNKPAGENALTVKEPTGPVGAKVTNFENLDFDAEDDETLQAAAMANAQNAIAEAQRKARNFNNDDEPDEDGEMNFQNPTGLGDVEIEQPKLLTATLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTIQSISVMAYLAEHHDIWGPFLVVAPASTLHNWEQEIKRFVPDLKIVPYWGSASDRKILRKFWDRKHSTYKRDAQFHVAITSYQMVVSDVAYFQKMKWQYMILDEAQAIKSSQSSRWKCLLSFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHEEFSDWFSKDIESHAQSNSKLNEDQLKRLHMILKPFMLRRVKKHVQKELGDKIELDVYCDLTYRQRAYYANLRNQISIMDLIEKATLGDDNDSGTLMNLVMQFRKVCNHPDLFERADTSSPLALVRFAETGSFAREGNDVTVGYTTRSVVEYILPRLLWRDGGRLTKAGSDNPSAGFRSRYLGEMMNIWSSTNIRESVDGTDNFSFLRFADTSIAEAEKVGKTDLFARASELAQRRNRLANMHVSYDDDEEDNFTPAHALFLIRQRQDRTALSEITSEGALQNLMNVSHVMYEDANLPRMDQAARPGASAPPIEVVCHTSSTQIERDRVLFNVPMRKALFGPNLDEQKEFVLQKVPVEQLPPAPLLPKPDNERQRFTSITVPSMRQFITNSGKLAKLDELLFKLKAGGHRVLLYFQMTRMIDLMEEYLTYRNWKYCRLDGSTKFEDRRDTVHDFQTNPSIFVFLLSTRAGGLGINLTSADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITRGTIEERIRKRAMQKEEVQRVVITGGAGASSGVDFSGRRAPENRNRDIAMWLADDDQAELIERRERELLESGELDKVAKKRGGGKRKKVAKDMGDGGGVSLDEMYHEGEGNFDDNKLSGAATPNVPDSTDAKPGKKKKATGKKAKTTKQRLAIADGQMDM
What is the function of this protein?
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
What are the official names of this protein?
Chromatin-remodeling ATPase INO80.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PI4KB_PLEMO
Sequence: MGDTVVEPAPLKPTSEPTSGPPGNNGGSLLSVITEGVGELSVIDPEVAQKACQDVLEKVKLLHGGMAVSSKGAPLELVNGDGVDSEIRCLDDPPAQIREEEDEMGATVASGTAKGARRRRQNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVYRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKPAHRKRELPSLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENRIRSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNISQFSVDSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM
What is the function of this protein?
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP).  May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation (By similarity).  Involved in Golgi-to-plasma membrane trafficking (By similarity).
What are the official names of this protein?
Phosphatidylinositol 4-kinase beta, PI4K-beta, PI4Kbeta, PtdIns 4-kinase beta.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
What are the subcellular locations of this protein?
Endomembrane system. Mitochondrion outer membrane; Peripheral membrane protein. Rough endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus. Golgi apparatus membrane. Note=Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex. Recruited to the Golgi apparatus membrane by ACBD3, GGA2 is also involved in the recruitment.
Protein: OST4B_ORYSJ
Sequence: MFDDQDLGFFANFLGIFIFVLVMAYHFVMADVKYEGN
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4B.
What is the protein family that this protein belongs to?
Belongs to the OST4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: CYBR1_MOUSE
Sequence: MAMEGYRGFLGLLVSALLVGFLSVIFVLIWVLHFREGLGWNGSGLEFNWHPVLAVTGFVFIQGIAIIVYRLPWTWKCSKLLMKSIHAGLNAVAAILAIISVVAVFEYHNVQKVPHMYSLHSWVGLTALILYIQQLVVGFFVFLLPWAPPSLRAIVMPIHVYSGLLLFGTVIATVLMGVTEKLFFVLKHPSYHSFPPEGVFTNTLGLLILVFGALIFWIVTRPQWKRPREPGSVPLQLNGGNAECRMEGAIAISSAHSMDAADPADAESSSEGAARKRTLGLADSGQRSTM
What is the function of this protein?
Plasma membrane reductase that uses cytoplasmic ascorbate as an electron donor to reduce extracellular Fe(3+) into Fe(2+) (PubMed:17068337).  Probably functions in dietary iron absorption at the brush border of duodenal enterocytes by producing Fe(2+), the divalent form of iron that can be transported into enterocytes (PubMed:11230685, PubMed:12547225).  It is also able to reduce extracellular monodehydro-L-ascorbate and may be involved in extracellular ascorbate regeneration by erythrocytes in blood (PubMed:17068337).  May also act as a ferrireductase in airway epithelial cells (By similarity).  May also function as a cupric transmembrane reductase (PubMed:18498772).
What are the official names of this protein?
Plasma membrane ascorbate-dependent reductase CYBRD1, Cytochrome b reductase 1, Duodenal cytochrome b.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Note=Localized at the brush border of duodenal cells.
Protein: SL1_ECHCS
Sequence: MGRFIFVSFGLLVVFLSLSGTEAGVCCPLGWSGYDQNCYKAFEELMNWADAEKFCTQQHKGSHLVSLHNIAEADFVVKKIVSVLKDGVIWMGLNDVWNECNWGWTDGAQLDYKAWNVESNCFIFKTAENHWSRTDCSGTHSFVCKSPA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 1, C-type lectin 1, CTL-1.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: ORN_BURVG
Sequence: MTDIAASASQPALVRNELNLVWLDMEMTGLDPDNDRIIEIAVVVTNSTLDIAVEGPVFAIHQSDETLAKMDDWNKSTHGRSGLIDRVRASTVTEAQAAAQLQAFLADYVSPGKSPMCGNSICQDRRFMARWMPEFERFFHYRNLDVSTLKELCRRWQPAIYKGFQKRAMHTALADIHESIDELKYYREHFLIPAAPASAA
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_STAA8
Sequence: MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLKDVMDKRERDINRDIDDAEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQEQIIHEANVRANGMIETAQSEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQKALVDKYLKEAGDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: OASD_COMTE
Sequence: MSNVKKHVSTINPVGEVLDVGSADEVQWSDASDVVVVGWGGAGASAAIEAREQGAEVLVIERFSGGGASVLSGGVVYAGAVPATRRKPASRFTEAMTAYLKHEVNGVVSDETLARFSRDSVTNLNWLEKQGATFASTMPGYKTSYPADGMYLYYSGNEVVPAYGNPQLLKKPPPRGHRVVAKGQSGAMFFAALQKSTLAHGARTLTQARVQRLVREKDSGRVLGVEVMVLPEGDPRTERHKKLDELVAKSACIRRRVPRRVAVNVRRSRARSARSATSVPAKVWCCPLAAISSIRNCWSMRRYKPGWLTGAAGCDGSGLRLGQSVGGIAQDLNNISAWRFITPPSVWPKGLVVNIQGERFCNEQVYGAKLGYEMMEKQGGQAWLIIDSNVRRQAAWQCLFGGLWAFQSMPALALMYKVAIKGKSVDDLAKKLRMDAAVLQLQFDRANAPARGEIEDPLGKSQDMRHEFKGGSLFAIDISISQKMFPLAVLSLGGLKVNEDNGAVIDGAGYDIPGLYAAGVPPLVWLPRVT
What is the function of this protein?
Involved in the degradation of steroids having an A:B ring fusion in a trans configuration.  Catalyzes the elimination of hydrogens located at positions 4 and 5 and the introduction of double bonds into ring A.
What are the official names of this protein?
3-oxo-5-alpha-steroid 4-dehydrogenase, Delta 4, 5-alpha steroid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NU4LM_TRAOB
Sequence: MPIIYMNIMLAFLISLLGMLFYRSHLMSSLLCLEGMMLSLFIMSTLMALNMHFPLANIVPIALLVFAACEAAVGLALLVSISNTYGLDYIHNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.