PharMolix/UniProtQA huggingface dataset:
Protein: NEP_I77A4
Sequence: MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHLLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PB1F2_I80A6
Sequence: MEQEQDTPWIQSTEHTNIQKRESGQQTQRLEHPSLTRLMDPYPRTMNRADTHKQIVSWRQWLSLKNPTQGSLKTRVSKRWKLFSKQEWTN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: GLYR1_AEDAE
Sequence: MTDSKGYAVNDLVWAKMKGFSPWPGRISEPPAELRRITVKKNIPVRCIFFFGSNNYAWIEETQIKPYQEFKEKLLSSCKSAGFKEAVQQIEEFIASPENFQHLFASEQDNRPDPDVEFNKLREGGTESGEETTVNNTSTPAALESVETTPVTAKKSAAKKKVRASLPIKLHVDKVVVFRSVAASTTKARAIGNKAKAAAALNDTSSPKRKRKILNDTAGDVSSLDLDTFSPVRRNVPVSHLLNRPTVARPATPEIDMTSVSNALQSRNIQASNLKFGFLGLGIMGCGMVKNLLNSGHSVVVWNRTATKCRKFQEAGAEVADTPSDVIEMTDVTFSCVADPQVAKELVFGNCGVMSANLVGKGYVEMTGVDPETSHDIAEQIIAKGGRYLEAQIQGSKNQAEEGTLIILAAGERLLFEECQTCFEAISRNSFYMGDVGNATKMNLVLQMISGVMLAGIAEGLALADRAGLQQKDVLEVLELTSMSSELVMQKGNAIIKGEFPPQQALKHMQKDLKLALNMAEGLEQPLPITAASNEVYKHAKRLGYGSHDSSAVYVRARF
What is the function of this protein?
Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation and colocalizes with a subset of trimethylated 'Lys-36' histone H3 (H3K36me3)-enriched regions.
What are the official names of this protein?
Cytokine-like nuclear factor N-PAC, NPAC, Glyoxylate reductase 1 homolog, Nuclear protein NP60 homolog, Putative oxidoreductase GLYR1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. NP60 subfamily.
What are the subcellular locations of this protein?
Chromosome.
Protein: IF1_ENTFA
Sequence: MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHYIRILPGDKVTVELSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_STRAG
Sequence: MAIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNVIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEALRWGAEVFHALKKILKERGLETAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFYDAERKVYDYSKFEGEGGAVRTAAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGGRVQLVGDDFFVTNTDYLARGIKEEAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLDKCGR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ERD22_XENLA
Sequence: MNVFRLSGDLCHLAAIIILLLKIWNSRSCAGISGKSQLLFAMVFTTRYLDLFTSFISLYNTSMKVIYMGCAYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSVLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLFNWIWRFSFEGFFDLIAIVAGVVQTILYCDFFYLYVTKVLKGKKLSLPA
What is the function of this protein?
Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum (By similarity).  Binding is pH dependent, and is optimal at pH 5-5. 4 (By similarity).
What are the official names of this protein?
ER lumen protein-retaining receptor 2, KDEL endoplasmic reticulum protein retention receptor 2, KDEL receptor 2.
What is the protein family that this protein belongs to?
Belongs to the ERD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.
Protein: RPOA_PSYCK
Sequence: MMLNATEFLTPNAINVDTVNETIAKVTLEPLERGFGHTLGNALRRILLSSLPGAAVIEAEIDGVDHEYSTLEGLQEDVLDLLLNLKGLAITLHDQNEVFLTLDKQGPGTITAADITLPHNVDIINPELVLGTLSDRGHLKMRLRVVMGRGYEPANQRREDGDTKAIGRLKLDASFSPVLRVAYQVENARVEQRTDLDRLIIELETNGTIDPEEAIRKAATILQQQISIFVDLEAEEAPEPVKEKEEVDPVLLRPVDDLELTVRSANCLKAENIYYIGDLVQRSETELLKTPNLGKKSLTEIKDVLASKDLELGMRLDNWPPADLRVDDRFSYRSR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: VSP_CRODC
Sequence: VVGGDECNINEHRFLVALYANSSLLCGGTLINQEWVLIAAHCDR
What is the function of this protein?
Thrombin-like snake venom serine protease that coagulates fibrinogen by inducing a fast degradation of the alpha chain (FGA) from human citrated plasma, and a slow degradation of beta chain (FGB).  Potently induces platelet aggregation in both platelet rich plasma and washed platelet preparations in a concentration-dependent fashion.  Shows amidolytic activities.
What are the official names of this protein?
Thrombin-like enzyme F202, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: T2D5_HAEIN
Sequence: MLYYVPRREKSYMNIKPHLFGLNRSNRDFSLRETWGKNQFNSSFPVSLCCYMSSKGILANYLSIENAEIKCSSIDIKDVFEIEPENENTFFAFETSHSIKLTALPDHTTCDLTDADFGSEIVIRPDSIVYLACSLAEILKESLANCMDIPNNVDHLDWSEPKQVIPLFPHILSTLNNLCSRADTIQTPFLLQPVWKTLGKSPRLADNCLDIFIWSDVAFVKFILEISNLNVNVLSINRQTRTAIWLYKMLVDIVKYGRFNHHKIIDLCSYNTKNDKAFASSGMITNVFMKSERLERPIIMKSEIKNIILGGGQELLSPERRFDAIIYNSSELFR
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GRCGYC-3'; the cleavage site is unknown.
What are the official names of this protein?
Probable type II restriction enzyme HindVP, R.HindVP, Endonuclease HindVP, Probable type-2 restriction enzyme HindVP.
Protein: MTSA_STRPQ
Sequence: MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK
What is the function of this protein?
Part of an ATP-driven transport system.
What are the official names of this protein?
Metal ABC transporter substrate-binding lipoprotein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: THYX_MYCA1
Sequence: MAEIAPLRVQLIAKTDFLAPPDVPWSTDADGGPALVEFAGRACYQSWSKPNPKTATNAGYIKHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPENDSRVVVPPGLDDDPELQQILAAAADASRATYTELLARLEAKFADQPSAVLRRKQARQAARAVLPNATETRIVVTGNYRAWRHFIAMRASEHADVEIRRLAIECLRRLADVAPAVFADFEIATLADGTEVATSPLATEA
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: COAW_STAAW
Sequence: MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLEK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type II pantothenate kinase, PanK-II, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type II pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_BAUCH
Sequence: MQILVDHSQKLRRSVTMKIASHIIEETISKKLLELAKTVVIDGFRKGKAPIHIVAKRYHNYLCQDVLYQLMHQQFIAAMLKEKINVISTPNYTYSTYQKDKDLIYQVEFEISPQVELKGIDTITVEKPLVQIKETDIDAMLTQLIKQNGSWEKTNNAAKITDRVTIDLYGTIENKRLKGSQAKNLNFTIGINNKHIIPGLENGIIGHKAGDNFNINIYLPDEYFPLELRGKLAIFTVALKKVEQYRLPHLDESFIKLLGVVDGTVEGLRNKIRKDIEVLLKNAVRNYIKEQVINYLLSVNNIDVPDIMIEQEIQIIKQKNTKHIGRIRKSALEQSRELIEAQAKRRIQITLLLIEIIKQHDIKVNTARMRAIMEEMAYLSPQKQEIINSYNSQSSMRRQISNIVLEEQAIEALLMKANVIEKKIDFADFMSKLSHS
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ETFA_PARDE
Sequence: MAVLLLGEVTNGALNRDATAKAVAAVKALGDVTVLCAGASAKAAAEEAAKIAGVAKVLVAEDALYGHRLAEPTAALIVGLAGDYSHIAAPATTDAKNVMPRVAALLDVMVLSDVSAILDADTFERPIYAGNAIQVVKSKDAKKVFTIRTASFDAAGEGGTAPVTETAAAADPGLSSWVADEVAESDRPELTSARRVVSGGRGLGSKESFAIIEELADKLGAAVGASRAAVDSGYAPNDWQVGQTGKVVAPELYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQIADYGLVGDLFSVVPELTGKL
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases.  It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, Alpha-ETF, Electron transfer flavoprotein large subunit, ETFLS.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: CORA_BACSU
Sequence: MKAHTGKDWFWYQMGPQERSKARDLIHFSHWPQCEKWFENNHHVNFLRVDTTETENEAVFGSIVYDQGLGEEKDHTVFHFYITRQYFFTINFDFSILREIKGKEVVRQMERADNAIEGFLILLGELMNAYLIGVDEFEVKLRKLRWQIKDDNSKSILNRVHLLRHELMIWKNLILSAKKIEMALKETFLPQNEGKKDYQRTQLKIDRGFTYISEFEGELNNLLHSEEVITSHRGNEIVKALTIFTTLFTPITALGALWGMNFSVMPELNWKYGYLFSLLLIVTSTVLIYLYLRKKGWTGDMLQERKKKKKPRKRRTL
What is the function of this protein?
Mediates influx of magnesium ions.  Alternates between open and closed states.  Activated by low cytoplasmic Mg(2+) levels.  Inactive when cytoplasmic Mg(2+) levels are high.
What are the official names of this protein?
Magnesium transport protein CorA.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMFO_RHOCB
Sequence: MDRLHIIGAGLAGSEAAWQAAQAGVPVVLHEMRPRVGTFAHRSGDFAEMVCSNSFRSDDDERNAVGLLHWEMRAAGGLIMATADRHALPAGGALAVDREAFSGAVTAALRAHPLISVAEEEITELPAEGHWIIATGPLTSGALAESIRAVTGAESLAFFDAIAPIVHAETTDIRCLRQSRYDKGETEEERTAYINCPMTRDQYEAFIDALLAAEKTEFHAGETAGYFDGCLPIEVMAERGRETLRHGPMKPVGLTNAHDPATKAYAVVQLRRDNALGTLYNIVGFQTKMKYGAQTAVFKMIPGLEQASFARLGGIHRNTFLNSPTLLDDQMRLRARPNLRFAGQVTGVEGYVESAAMGLLAGRMAAAGILGRSLPPPGPETAMGALVNHITGGAVAKTFQPMNVNFGLFPPLDDARGGRRGRKDRYKGYTDRAKEVFTAWLAAQA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_MYCSS
Sequence: MPPTINMGIPGASSSVTGGVSGKRVLLAEPRGYCAGVDRAVETVERALEKHGAPVYVRHEIVHNRYVVDTLAKAGAVFVEQTDEVPEGAIVVFSAHGVAPTVHVEAAARNLKTIDATCPLVTKVHNEAKRFARDDYDILLVGHEGHEEVVGTAGEAPDHVQVVDNPDAVDKVTVRDPDKVIWLSQTTLSVDETMETVRRLREKFPTLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSKNSSNSVRLVEVALGAGSDAAHLVDYAEDIDPTWLNGVTTVGVTSGASVPEVLVRGVLDRLAEYGYGTVQPVTTANETLVFALPREIRPARS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: WHI2_YEAST
Sequence: MDDIITQVSPDNAESAPILQEQQQQQNSQYEGNEEDYGDSLIHLNIQENHYFITRDQLMSLPESLLLCLFPSGVFLDRCGQVITNLTRDDEVYIVNFPPDCFEYIMEIYTKAHDDLYNHPVEKFFDRPSSSFVSNAKGFFGLSSNNSISSNNEQDILHQKPAIIVLREDLDYYCVPQEEFQFDSTNEENNEDLLRHFMAQVKMAAGSYLTSKTSIFQGLYSSNRLKQQQQQQKIEKGSNSSSNTKSTSKKLGPAEQHLMDMLCSSGFTKETCWGNRTQETGKTVISSLSLCRLANETTEGFRQKFNEAKAKWEAEHKPSQDNFITPMQSNISINSLSASKSNSTISTARNLTSGSTAPATARDKRKSRLSKLADNVRSHSSSRHSSQTRSKPPELPKLYDLVPKPNINAKLLLFWRKPARKCWWGEEDIELEVEVFGSWKDESKKIIELILPTNVDPEAELHKIIVPVRLHIRRVWTLELSVIGVQ
What is the function of this protein?
Plays a role in the coordination of growth and proliferation.  Required for entry into G0 phase under conditions of carbon limitation.  Involved in the general stress response; acts together with PSR1 to activate stress response element (STRE)-mediated gene expression, possibly through dephosphorylation of MSN2.
What are the official names of this protein?
Growth regulation protein.
What is the protein family that this protein belongs to?
Belongs to the WHI2 family.
Protein: CDF3_ARATH
Sequence: MMMETRDPAIKLFGMKIPFPSVFESAVTVEDDEEDDWSGGDDKSPEKVTPELSDKNNNNCNDNSFNNSKPETLDKEEATSTDQIESSDTPEDNQQTTPDGKTLKKPTKILPCPRCKSMETKFCYYNNYNINQPRHFCKACQRYWTAGGTMRNVPVGAGRRKNKSSSSHYRHITISEALEAARLDPGLQANTRVLSFGLEAQQQHVAAPMTPVMKLQEDQKVSNGARNRFHGLADQRLVARVENGDDCSSGSSVTTSNNHSVDESRAQSGSVVEAQMNNNNNNNMNGYACIPGVPWPYTWNPAMPPPGFYPPPGYPMPFYPYWTIPMLPPHQSSSPISQKCSNTNSPTLGKHPRDEGSSKKDNETERKQKAGCVLVPKTLRIDDPNEAAKSSIWTTLGIKNEAMCKAGGMFKGFDHKTKMYNNDKAENSPVLSANPAALSRSHNFHEQI
What is the function of this protein?
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity).  Regulates a photoperiodic flowering response.  Transcriptional repressor of 'CONSTANS' expression.
What are the official names of this protein?
Cyclic dof factor 3, Dof zinc finger protein DOF3.3, AtDOF3.3, H-protein promoter-binding factor 2a.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTS_STRPZ
Sequence: MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREKGMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAEGKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNGGRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNESRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRFMLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFESEVAATMAAALNN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COTZ_BACSU
Sequence: MSQKTSSCVREAVENIEDLQNAVEEDCPTGCHSKLLSVSHSLGDTVPFAIFTSKSTPLVAFGNVGELDNGPCFNTVFFRVERVHGSCATLSLLIAFDEHKHILDFTDKDTVCEVFRLEKTNYCIEVDLDCFCAINCLNPRLINRTHHH
What are the official names of this protein?
Spore coat protein Z.
What is the protein family that this protein belongs to?
To B.subtilis CotY.
What are the subcellular locations of this protein?
Spore coat. Note=Outer coat.
Protein: PA21B_BOVIN
Sequence: MRLLVLAALLTVGAGQAGLNSRALWQFNGMIKCKIPSSEPLLDFNNYGCYCGLGGSGTPVDDLDRCCQTHDNCYKQAKKLDSCKVLVDNPYTNNYSYSCSNNEITCSSENNACEAFICNCDRNAAICFSKVPYNKEHKNLDKKNC
What is the function of this protein?
Secretory calcium-dependent phospholipase A2 that primarily targets dietary phospholipids in the intestinal tract.  Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines.  May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation in the intestinal tract.  Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines (By similarity).  May act in an autocrine and paracrine manner (By similarity).  Has anti-helminth activity in a process regulated by gut microbiota.  Upon helminth infection of intestinal epithelia, directly affects phosphatidylethanolamine contents in the membrane of helminth larvae, likely controlling an array of phospholipid-mediated cellular processes such as membrane fusion and cell division while providing for better immune recognition, ultimately reducing larvae integrity and infectivity (By similarity).
What are the official names of this protein?
Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted from pancreatic acinar cells in its inactive form.
Protein: BEX4_PONAB
Sequence: MESKEELAANNLNGENAQQENEGREQAPTQNEETRHLGGGEGQKPGGNIRRGRVRRLVPNFRWAIPNRHIEHNEARDDVERFVGQMMEIKRKTREQQMRHYMRFQTPEPDNHYDFCLIP
What is the function of this protein?
May play a role in microtubule deacetylation by negatively regulating the SIRT2 deacetylase activity toward alpha-tubulin and thereby participate in the control of cell cycle progression and genomic stability.
What are the official names of this protein?
Protein BEX4, Brain-expressed X-linked protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the BEX family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle pole. Nucleus. Cytoplasm. Note=Also localizes to microtubules.
Protein: I20L2_MOUSE
Sequence: MSTILLNLDFGQPSKKAFGGNAKHQRFVKKRRFLEQKGFLNKKNQPPNKVSKLNSEPPKKGETSRVDGILKILPCPKKKEAAASKRDSERSKDKKAPLSWLTPAPSKKTASVVSKIDLLGEFQSALPKTKSTQKKGSKKKSLKKKIATENSTQAQSKDKGSKKKPLKKNAVPNSTQARSEDKCPTVPQNLPGKMVAIDCEMVGTGPKGRVSSLARCSIVNYNGDVLYDEYVLPPCYIVNYRTRWSGIRKCHMVNATPFKTARSQILKILSGKVVIGHAIHNDYKALQYFHPKSLTRDTSRIPLLNRKADCPENVTLSLKHLTKKLLSRDIQVGNTGHSSVEDAQATMELYKLVEVEWEQHLAQNPPEN
What is the function of this protein?
3'-> 5'-exoribonuclease involved in ribosome biogenesis in the processing of the 12S pre-rRNA.  Displays a strong specificity for a 3'-end containing a free hydroxyl group.
What are the official names of this protein?
Interferon-stimulated 20 kDa exonuclease-like 2.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FMT_PROM5
Sequence: MRIIFWGTPEYSVKSLEVLKKSDHEILAVITQPDKKRSRGNKLIASPVKQYAMKEGLPVFTPETLKKNDHFISLLKEFSCDLFVVIAYGKILPKKILDIPKYKSWNAHASLLPRWRGAAPIQWSILEGDDFTGVGIMRMEEGLDTGDVLVEKQIKIEKEDNLQTLTKKLSDLSSELLLKAISKIEQNKNKDINHLLKKQKDLQRKLKYARMINKSDYIIDWANNSTDIYRKINALYPRVSTTFKKKNLKIIKIKILTTDEIQNKNYKIVSDKFKPGYVIGLIENKGIIISTKTDPILLLEAKLEGKNISKQKQLLQQLNPLIGEKFSD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.