PharMolix/UniProtQA huggingface dataset:
Protein: MURQ_PHOLL
Sequence: MKINLNNMVTESRNPASANIDTLPTLEMLKLINDEDKKVALAVEQTLPKIAETVDKIAEAFRQGGRLIYIGAGTSGRLGILDASECPPTYGTKPEQVVGLIAGGHQAILHAVENAEDNQQLGANDLQALHFNSKDVLVGIAASGRTPYVLGAMTYAKSVGATVACISCNPESPMTQAADIAIAPIVGPEIVTGSSRMKAGTAQKLILNMLTTGAMIRTGKVYSNLMVDVEATNAKLVERQKNIVIAATECNREQAEQALAECDGHCKTAIVMILAGINAQQAKTLLKKHHGFIRPTISAVR
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: RPOC1_ZYGCR
Sequence: MIPEDHLQYIRIGLASPEQIRSWAERRLPNGELIGRVSKPYTIHYQTHKPEKDGLFCERVFGPIKSGVCACGKYQGTISTKDSPKYCEKCGVEFTEARVRRHRMGYIDLQCPVTHVWYLKNRPSVIARLLNQPLQDIESLVYYDSFLARPVTNEPTLIRLLPTQSKLYKDRSQSTFDKPLELFLFDEPWQSALSNFFSPKWFHLIQIREMLTGADVIHKLLSGLNLTNAMFHARNQWKHLAKKAPESQSEVIEAQGPVPQAEEEKQRDQSIQQQKDAVLRRITLIRDLLQSQTQPEWMVLRTLPVLPPDLRPILELKDGQLIRSDLNELYRRVLYRNQLICQFSVEDPFCISMMQKKLLQQAIDSLLANGAGGNIIRDRNMRPYKSLSDIIKGKKGRFRENLLGKRVDYSGRSVIVVGPYLSLYQCGLPREMAIELFQPFVIRGLIINHFARNPRAAKSMIQRRHPIVWKILKMIVDDHLVILNRAPTLHRLGVQAFQPVLVRERAIHLHPLVCTGFNADFDGDQMAVHVPLSLEAQAEAHLLMSPYFNLLSPGTGDAIVVPTQDMLLGLYALTLGATLGIYSNINTYKYQSDVSFTQKTDSKIITFSNFSDALTAYHQGIITSDLPIWLYCRPEIAVMNNSQGDCPVEAQYQPKGIYLNVYEHSQIRTDKLGKTVQKYIRTTAGRAVLNQQIEQAIQGTEHAYKAVKQLNIILN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YLZ6_CAEEL
Sequence: MVGHSESSTDAVIEPTSEELLAEQVRVFNKMKGSTNFNRVAEDVYPVEVTKSKLVCEMVVQHQHLNSKGTLHGGQTATLTDVITARAVGVTVKDKGMASVELAVSYLLPVKVGDVLEITAHVLKVGRTMAFTDCEFRRKSDGKMSAKGKHTLAFLPNQPGISVENGTQF
What are the official names of this protein?
Putative esterase F42H10.6.
What is the protein family that this protein belongs to?
Belongs to the thioesterase paaI family.
Protein: RND1_HUMAN
Sequence: MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSELISSTFKKEKAKSCSIM
What is the function of this protein?
Lacks intrinsic GTPase activity.  Has a low affinity for GDP, and constitutively binds GTP.  Controls rearrangements of the actin cytoskeleton.  Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments.  Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
What are the official names of this protein?
Rho-related GTP-binding protein Rho6, Rho family GTPase 1, Rnd1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton.
Protein: RL13_ECOK1
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MET3_PHANO
Sequence: MANPPHGGVLKDLIARDAPRRQELYAEAEKLPAIVLSDRQLCDLELILNGGFSPLEGFMNEKDYTGVVAENRLADGNLFSIPITLDVSKETIDEVGVKAGARIALRDSRDDRNLAIITVDDIYKPDKVKEANEVFGDNDEAHPAVKYLHHTAKEFYVGGKVEAIDRLEHYDYVGLRYTPAELRLHFDKLGWQKVVAFQTRNPMHRAHRELTVRAARARQANVLIHPVVGLTKPGDIDHFTRVRVYQALMPRYPNGMAVLALLPLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGKNSKGVDFYGPYDAQDAVEKYRDELGIEVVPFQQMTYLPDSDEYKPKDEVAKDIKTLDISGTELRKRLRTGQEIPEWFSYPEVVKVLRESHPPRNQQGFTVFLTGYQNSGKDAIARALNVTLNQQGGRSVSLLLGETVRSELSSELGFSREDRDKNIARIAFVAAELTKAGAAAIVAPIAPFQKSRQQARETVEKYGSFFLVHVATPLDHAEKTDRRGVYAKARAGEIKGFTGVDDPYEAPENADLVVDTSKTNVRTAVHQIVLLLESQGLLTQL
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFV_RHOCA
Sequence: MTPDRTLALCDTTLRDGEQTAGVAFSLAEKKAIARALDRAGVAEIEVGIAAMGWAEVAEIRAVVAEIAHATPVVWCRLRMHDLDMAQKTGVKRVHFAVPTSTAQLEGKLRVDRDWILRETAALVFCASDRGLQVSVGAEDASRTDPDFLIRLAEVAAAAGAIRFRIADTLGLLDPLGAFRLVAELSARISLPIEMHAHNDFGMATANTIMAAHAGATHLSVTVNGLGERAGNAACEEVGAALEAGGIDTGLDLCALPELSAVVAKASGRAFRAQKPITGDDWLFAHESGIHVDAILKRADTYEDPRCAPARFGRERQIVIGKHSGSAGLRAALLEAGLPADDAVLDRLKPLLRAHAVRVKRPVEAGDLRRMVARLARPSPRT
What is the function of this protein?
This protein is a Fe-Mo-cofactor biosynthetic component.
What are the official names of this protein?
Homocitrate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: SELN_HUMAN
Sequence: MGRARPGQRGPPSPGPAAQPPAPPRRRARSLALLGALLAAAAAAAVRVCARHAEAQAAARQELALKTLGTDGLFLFSSLDTDGDMYISPEEFKPIAEKLTGSCSVTQTGVQWCSHSSLQPQLPWLNUSSCLSLLRSTPAASCEEEELPPDPSEETLTIEARFQPLLPETMTKSKDGFLGVSRLALSGLRNWTAAASPSAVFATRHFQPFLPPPGQELGEPWWIIPSELSMFTGYLSNNRFYPPPPKGKEVIIHRLLSMFHPRPFVKTRFAPQGAVACLTAISDFYYTVMFRIHAEFQLSEPPDFPFWFSPAQFTGHIILSKDATHVRDFRLFVPNHRSLNVDMEWLYGASESSNMEVDIGYIPQMELEATGPSVPSVILDEDGSMIDSHLPSGEPLQFVFEEIKWQQELSWEEAARRLEVAMYPFKKVSYLPFTEAFDRAKAENKLVHSILLWGALDDQSCUGSGRTLRETVLESSPILTLLNESFISTWSLVKELEELQNNQENSSHQKLAGLHLEKYSFPVEMMICLPNGTVVHHINANYFLDITSVKPEEIESNLFSFSSTFEDPSTATYMQFLKEGLRRGLPLLQP
What is the function of this protein?
Essential for muscle regeneration and satellite cell maintenance in skeletal muscle (PubMed:21131290).
What are the official names of this protein?
Selenoprotein N, SelN.
What are the subcellular locations of this protein?
[Isoform 2]: Endoplasmic reticulum membrane.
Protein: MUCK_ACIAD
Sequence: MYSNNQRSRIGSHTWKIAFLFAFLALLVDGADLMLLSYSLNSIKAEFNLSTVEAGMLGSFTLAGMAIGGIFGGWACDRFGRVRIVVISILTFSILTCGLGLTQSFIQFGVLRFFASLGLGSLYIACNTLMAEYVPTKYRTTVLGTLQAGWTVGYIVATLLAGWLIPDHGWRVLFYVAIIPVLMAVLMHFFVPEPAAWQQSRLAPSKQTETVKTSAFKLIFQDKRNRNMFILWALTAGFLQFGYYGVNNWMPSYLESELGMKFKEMTAYMVGTYTAMILGKILAGFMADKLGRRFTYAFGAIGTAIFLPLIVFYNSPDNILYLLVIFGFLYGIPYGVNATYMTESFPTAIRGTAIGGAYNVGRLGAAIAPATIGFLASGGSIGLGFVVMGAAYFICGVIPALFIKEKQYDPQQS
What is the function of this protein?
Probable uptake of muconate.
What are the official names of this protein?
Cis,cis-muconate transport protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTU3C_STAAR
Sequence: MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVMEAAGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAWCYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVVLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGLHHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLKDGVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKIVGGLMLSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVGIVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIKALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPDQVFAGKMMGDGVGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESESGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQGQPLMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGKLIMTVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in alpha- and beta-glucoside transport (By similarity).
What are the official names of this protein?
PTS system glucoside-specific EIICBA component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YOAH_SALNS
Sequence: MFAGLPSLSHEQQQKAVERIQELMSQGMSSGEAIAQVAGELRANHTGERIVARFEDEDE
What are the official names of this protein?
UPF0181 protein YoaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: ILVD_POLNS
Sequence: MKRLNERSRMVTEGVARAPNRSMYYAIGYEEKDFVKPMVGVANGHSTITPCNSGLQKLADAAVSALEGAGAKAQMFGTPTVSDGIGMGTEGMKYSLVSREVIADSIETCVNGLWQDGVVVIGGCDKNMPGGMMALARTNVPGIYVYGGTIKPGHYKGKDLNIVSAFEAVGEFTSGRLSEEDLKGVEQHACPGSGSCGGMYTANTMSSAFEALGMSLPYSSTMANEDAEKVASTHDSAVVLVEAIKKNLRPRDIITKKSIENAVSVIMAVGGSTNAVLHFLAITSAAEIDWTIDDFERIRKRVPVIVDMKPSGTYLATDLHQAGGIPQVMKILLDDGLLHGDCMTITGKTVAEVLKDVPSVPRADQKVIRTLDNPLYKQGHLAILKGNISPEGCVTKITGLKNPSITGPARVFDSEDDAMAAIMAQKIKDGDIVVIRYEGPKGGPGMREMLAPTSALVGQGLGESVGLITDGRFSGGTWGMVVGHVAPEAYVGGTIALIHEGDSVTIDAHKLLIQLNVDDAEIAKRRAAWKQPKPRYTRGLLAKYAKLASTASKGAVTDLNLND
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PP345_ARATH
Sequence: MTLLNYLHCNRSKSFLFQRFYSPYRIAHKLFDGSSQRNATTSINHSISESLRRNSPARALSIFKENLQLGYFGRHMDEVTLCLALKACRGDLKRGCQIHGFSTTSGFTSFVCVSNAVMGMYRKAGRFDNALCIFENLVDPDVVSWNTILSGFDDNQIALNFVVRMKSAGVVFDAFTYSTALSFCVGSEGFLLGLQLQSTVVKTGLESDLVVGNSFITMYSRSGSFRGARRVFDEMSFKDMISWNSLLSGLSQEGTFGFEAVVIFRDMMREGVELDHVSFTSVITTCCHETDLKLARQIHGLCIKRGYESLLEVGNILMSRYSKCGVLEAVKSVFHQMSERNVVSWTTMISSNKDDAVSIFLNMRFDGVYPNEVTFVGLINAVKCNEQIKEGLKIHGLCIKTGFVSEPSVGNSFITLYAKFEALEDAKKAFEDITFREIISWNAMISGFAQNGFSHEALKMFLSAAAETMPNEYTFGSVLNAIAFAEDISVKQGQRCHAHLLKLGLNSCPVVSSALLDMYAKRGNIDESEKVFNEMSQKNQFVWTSIISAYSSHGDFETVMNLFHKMIKENVAPDLVTFLSVLTACNRKGMVDKGYEIFNMMIEVYNLEPSHEHYSCMVDMLGRAGRLKEAEELMSEVPGGPGESMLQSMLGSCRLHGNVKMGAKVAELAMEMKPELSGSYVQMYNIYAEKEEWDKAAEIRKAMRKKNVSKEAGFSWIDVGDTEGSLTMQGFSSGDKSHPKSDEIYRMVEIIGLEMNLEGKVAV
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g32430, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y2296_ENT38
Sequence: MEMDLNNRLTEDETLEQAYDIFLELAMDNLDPADVILFNLQFEERGGAELFDPSEDWSEHVDFDLNPDFFAEVVIGLAETDGGEINDIFARVLLCREKDHKLCHILWRE
What are the official names of this protein?
UPF0263 protein Ent638_2296.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: HCP_GLOC7
Sequence: MFCEQCEQTASGNGCHQWGACGKSPEVNAVQDLLIYCLRGLATVVLKARENHIPTQKMDVFICEALFATMTNVNFNNKSLTEYLKTCINLREKLKQTLEETLNTPPSWSDLSNYQPDWEDSLVTQGETLVHRFISRSSNDLDIISLKLTVLYGLKGVASYTFHAQELGQEDEKVYQFIEDALVKLERTDLSLQEWIDLALKVGEINLRAMELLDAGHTQTYGHPTPTQVPLNPKKGKAILVSGHDIRQLEAILQQTADKDITVYTHGELLPAHGYPKLKQNYPHLYGHYGTAWQNQTKDFAKFPGAIIITTNCLMPPHETYDEKLFTIGPVSYPHLTYLPPTETGIPDYSPAIKKACLMPGFTEETEPRHVMVGFARNTVLSVSDQVIEGVKTGKIRHFFLVGGCDGAKPGRTYYTELVEKVPSDCIVLTLACGKFRFFDKQLGEIEGLPRLMDVGQCNDAYSAIQIALGLANAFNVSVNEIPLSLILSWYEQKAIAVLLTLLYLGIQNIRLGPTLPAFITPNVLQFLQDNYHLQPITTPDEDLAACLN
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIP18_ARATH
Sequence: MVTGNFNLEKLLKNLKKKTGKKAEILTMNEKVEKEDVVQNEANEQETVTKKNEEGDIVDKKDETPEVEEKIDKPETSTRKLEIHIAFLSEKYEADIGKVISKFEGVKTCKVDVENKKVVITGDFDEEKLWKELEEKMRKRIVKMEKEKKDDEPITKDEENEIDRGVYMNPSSDDEKEMARWMMFSDENPNACSIS
What is the function of this protein?
Probable heavy-metal-binding protein (By similarity).  Required for female gametophyte development and function (PubMed:15634699).
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 18, AtHIP18, Protein maternal effect embryo arrest 56.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: RL29_BORDL
Sequence: MLKNLKDLTLEDMKAKRLTLKKEYMDLRFKTVVGHVENPLKKRELRRDIARLNTIIHEYAIGIRKV
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DDX43_HUMAN
Sequence: MSHHGGAPKASTWVVASRRSSTVSRAPERRPAEELNRTGPEGYSVGRGGRWRGTSRPPEAVAAGHEELPLCFALKSHFVGAVIGRGGSKIKNIQSTTNTTIQIIQEQPESLVKIFGSKAMQTKAKAVIDNFVKKLEENYNSECGIDTAFQPSVGKDGSTDNNVVAGDRPLIDWDQIREEGLKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAERFKAHQQKREMERKMERPQGRPKKFH
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX43, Cancer/testis antigen 13, CT13, DEAD box protein 43, DEAD box protein HAGE, Helical antigen.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: RSEP_PHOLU
Sequence: VEKVIPGSAAEKAGLQKGDRIVKVGSQEIDVWHTFTSFVSNNPNVPLELSVDRAGHIISLSMTPEVRQQSGGRKVGFAGVELRIVPLADEYKIVQQYGPFSAMYQAGDKTWQLMRLTVSMIGKLIVGDVKINNLSGPISIAKGAGVSADSGLVYYLMFLALISVNLGIINLIPLPVLDGGHLLFLFIEKIKGGPVSERVQDFSYRIGAMILVLLMGLALFNDFSRF
What is the function of this protein?
A site-2 regulated intramembrane protease (S2P) that cleaves the peptide bond between 'Ala-108' and 'Cys-109' in the transmembrane region of RseA.  Part of a regulated intramembrane proteolysis (RIP) cascade.  Acts on DegS-cleaved RseA to release the cytoplasmic domain of RseA.  This provides the cell with sigma-E (RpoE) activity through the proteolysis of RseA (By similarity).
What are the official names of this protein?
Protease RseP, S2P endopeptidase, Site-2 protease RseP, S2P protease RseP, Site-2-type intramembrane protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDUS2_RAT
Sequence: MAALRAVCSLRGVGAQVLRAGSGIRLPSQPSRGARRWQPDIEWAEQFSGAVMYPSKETAHWKPPPWNDVDVLKEKVVTNVTLNFGPQHPAAHGVLRLVLELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRILNHIMAVTTHALDIGAMTPFFWMFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLMDDIYEFSKNFSLRIDEVEEMLTNNRIWRNRTVDIGVVSAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQSLRIIEQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEIDR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30922174).  Essential for the catalytic activity of complex I (PubMed:30922174).  Essential for the assembly of complex I (By similarity).  Redox-sensitive, critical component of the oxygen-sensing pathway in the pulmonary vasculature which plays a key role in acute pulmonary oxygen-sensing and hypoxic pulmonary vasoconstriction (PubMed:30922174).  Plays an important role in carotid body sensing of hypoxia (By similarity).  Essential for glia-like neural stem and progenitor cell proliferation, differentiation and subsequent oligodendrocyte or neuronal maturation (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial, Complex I-49kD, CI-49kD, NADH-ubiquinone oxidoreductase 49 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y555_BACCQ
Sequence: MGFPKEGEKVQIHSYKHNGSIHRMWEETTILKGTQSLVIGANDRTVVTESDGRTWITREPAICYFHANYWFNVIGMLREEGVYYYCNLSSPFAYDSEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHSQIMQYPPVIDTILKRNVAQLTQWIHQRKGPFAPDFVDMWYERYLMYRN
What are the official names of this protein?
UPF0374 protein BCQ_0555.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: TULP2_AEDAE
Sequence: MEAYIRQKRATPGMVQASDMQLVRPMSAVNRNGREVHAYDGPMQFMMSPNNPDQILTSTGNASITTTPTSPYSDAPLEKLTPSSQDSEDEESTPVDILPSSNSFDSTRHSADHLLTHSAPISPALMNNNGGSHHDSSSGKSVEHSSPQASGHNDTEGDVVGPIEQWVTQPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKKVFCLAGRKRKKSKTSNYIISCDPTDLSRQADGFVGKLRSNVFGTTFFVYDSGKKEDHGNPRLDLAVVIYDTNILGFKGPRNMTVLLPGMTEDDQRVKISSADGQQGLLDSWKSKNMDNVVELHNKTPIWNDETQSYVLNFHGRVTQASVKNFQLVHDSDPDYIVMQFGRTSDDIFTMDFRYPLCAFQAFAIALSSFDGKLACE
What are the official names of this protein?
Protein king tubby 2.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ISPG_BLOPB
Sequence: MNNVTNIVRRKSTRIYIGNVPIGDGAPIAVQSMVNTRTTDILETVTQINALKKAGVDIVRISIPTMDAAEAFKIIKQQVINTPLVADIHFDYRIALKVAEYGADCLRINPGNIGNNKRIRSVVHCAQDKNISIRIGVNSGSLERDLQKKYDGNPTENVLLESAMRHVDILDKLNFHQFKVSVKSSDVLITIQAYRALASKIDQPLHIGLTEAGALRNGTVKSAMAVGFLLNEGIGDTIRISLATDPIEEVKVAFDILRALRIRAHGINFIACPGCARQEFNVINVVNALEEKVSDITTPMDVSIIGCVVNGPGEALKSTIGVAGARNKSGIYEDGIRQKKRCDNISIIEELERRIRAKSKLLDPNNHNITPTTYNK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: FTSZ_ENTHR
Sequence: MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITANTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQALREALDGADMIFITAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVDTLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTVMENQGTALMGIGVASGEERVIEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEAQDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQTQMQSSTQKTVLDMDQAKPISAEEENSSFGDWDIRREQNVRPRVEETNFEPIEKKEFDTFNREETKAKGDDELSTPPFFRSK
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: NCAP_PI3B
Sequence: MLSLFDTFSARRQENITKSAGGAVIPGQKNTVSIFALGPSITDDNDKMTLALLFLSHSLDNEKQHAQRAGFLVSLLSMAYANPELYLTSNGSNADVKYVIYMIEKDPGRQKYGGLVVKTREMVYEKTTDWMFGSDLEYDQDNMLQNGRSTSTIEDLVHTFGYPSCLGALIIQVWIILVKAITSISGLRKGFFTRLEAFRQDGTVKSSLVLSGDAVEQIGSIMRSQQSLVTLMVETLITMNTGRNDLTTIEKNIQIVGNYIRDAGLASFFNTIRYGIETRMAALTLSTLRPDINRLKALIELYLSKGPRAPFICILRDPVHGEFAPGNYPALWSYAMGVAVVQNKAMQQYVTGRSYLDIEMFQLGQAVARDAESQMSSILEDELGVTQEAKQSLKKHMKNISSSDTTFHKPTGGSAIEMAIDEEAEQPESRGDQDQGNEPQSSIVPYAWADETRSDTQTESVTEIESIKTEQRNIRDRLNKRLNEKRKQSDPKSTNIANDTNQTEIDDLFSAFGNN
What is the function of this protein?
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: GET4_SALSA
Sequence: MSEQEALKCSSARNRGGTQRVEGKLRASVEKGDYYEAHQMYRTLFFRYISQAKHTDARELMYNGAQLFFSYNQLNSAADLSMLVLESLEKSEAKVEDEDLEHLAKLFSLMDPNSPERVAFVSRALKWSTGGSGKLGAPKLHQLLAVTLWKEQNYSESRYHFLHSSDGEGCAQMLVEYSAQRGFRSEVDMFVAQAVLQFLCLKNKNSASVVFSTYTQKHPSIEKDPPFVQPLLNFIWFLLLAVDGGKLTVFTVLCEQYQPSLKRDPMYNEYLDRIGQLFFGVPPKQSSSYGGLLGNLLNSLMGSGEDEEGEEAQEHGSPIELD
What is the function of this protein?
As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation.  The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane.  Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum.  The bag6/bat3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome.  It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
What are the official names of this protein?
Golgi to ER traffic protein 4 homolog, Conserved edge expressed protein.
What is the protein family that this protein belongs to?
Belongs to the GET4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.