PharMolix/UniProtQA huggingface dataset:
Protein: PYRH_XYLFT
Sequence: MRYPMSKLAYHRVLLKLSGEALMGSADYGIDPKVINRLAGEVIEAQNAGAELALVIGGGNIFRGAGLAAKGMDRVTGDQMGMLATIINALAMQDALEKLGTKVRVMSAIKINNVCEDFIRRRAIRHLEKSRITIFAAGTGNPFFTTDSGAALRAIEIGADLLLKATKVDGIYNKDPQKHCDAVKYSTLSYDEVISQNLEVMDTAAFALARDSNLPLRIFDIEQPGVLLRILHGEEIGTLVKERNSKS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPC31_MYCTU
Sequence: MFLLDANVLLAAHRGDHPNHRTVRPWFDRLLAADDPFTVPNLVWASFLRLATNRRIFEIPSPRAEAFAFVEAVTAQPHHLPTNPGPRHLMLLRKLCDEADASGDLIPDAVLAAIAVGHHCAVVSLDRDFARFASVRHIRPPL
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Upon expression in M. smegmatis inhibits colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB31 (By similarity).
What are the official names of this protein?
Ribonuclease VapC31, RNase VapC31, Toxin VapC31.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: PYRE_PYRAE
Sequence: MIKRLVDIGAVKFGAFKLSSGLESPFYVDLRSVLGEPELFQWVIERYEAVLSGLEFDVIIGVATGGIPYASVLGYRLKKPMGYVRDEAKGYGTGRQIEGADVAGKRAAVVDDVLTTGKSVLNAIRAVRASGGEVAGVVVFLDRGQCGAEAVKREAGVYVYSVYKMRELLEELRPHIGEERYRSVLDYLSQWRC
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RIMP_STAHJ
Sequence: MSKITEEVETIITPILDELNFELVEVEYTKEGKDHFLRISIDKEGGVNLNDCTLASEKISEAMDENDPIPDMYYLDVASPGAERPIKKEKDYHNAIDKPVFVSLYAPIEGDKEWLGILKAVDDDTITMEVKEKAKTKQIEIPRNKIAKARHAVMI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUT4_BOVIN
Sequence: MRARWGRRGARRGGPGLPGTHLALLAASLLSSSVAIYVCWKQLPPLPWASPSPPRPVNVLLWWEPFRGRHNPRRPPPDCQRRFNISGCVLHTDRAAYEEAQAVLFHHRDLVKGPPDWPPPWGVQMPPVEEREGLVMDDEGQEAEAETSAALGPRPAGQRWVWMNFESPSHSPGLQGLAGNIFNWTLSYRADSDIFVPYGYLYPRTHPSEQPPGLVPPLARKQGLVAWVVSNWDERQARVRYYRQLSQYVTVDVFGKGGPGQPLPDAELVHTVARYKFYLAFENSQHLDYITEKLWRNAFLAGAVPVVLGPNRTNYERFVPSNAFIHVDDFPSASSLAAHLQFLDRNPTVYRGYFRWRRSHAVHVTSFWDEPWCLACQAVQKAGNQRKSVPNLAGWFQQ
What is the function of this protein?
Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins.  Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity.  Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins.  Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis (By similarity).  In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE (By similarity).
What are the official names of this protein?
Alpha-(1,3)-fucosyltransferase 4, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Fuc-TIV, FucT-IV, Galactoside 3-L-fucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: CCSA_PEA
Sequence: DPKETWAFITWTIFAIYLHTRKKKKLEGINSSIVASIGFLIIWICYFGINLLGIGLHSYGSFTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RIHA_SHESA
Sequence: MSRPIILDCDPGHDDAIALILALAHPELTPLAVTTSAGNQTPDKTLNNALRILTLLNRSDIPVAGGAVKPLSRELMIADNVHGETGLDGPALPAPSFQPQAVNAVELMAEKIRQSDKPVTLVPTGPLTNIALLLASHAELHAKIERIVLMGGAAGVGNWTPAAEFNIFVDPEAADIVFKSGIPITMCGLDVTHQAQIMDEDIERIRAIANPVAKCVAELLDFFMIYHRDPKWGFVGAPLHDPCTIAWLLNPALFDAQDCWVGIETQSELTLGMTVVDRYQLTGKPANATVLFGIDRQGFVDLLVDSLAVYTPTYLNRR
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: PTH_STRA1
Sequence: MVKMIVGLGNPGSKYNDTKHNIGFMAIDRIVKNLDVNFTEDKNFKAEIGSDFINGEKIYFIKPTTFMNNSGIAVKALLTYYNISIKDMIIIYDDLDMEVGKIRFRQKGSAGGHNGIKSIIAHLGTQEFDRIKVGIGRPNGRMTVINHVLGKFDKNDEIMISNTLDKVDNAVKYYLQTNDFQKTMQKYNGLK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF_BOMMO
Sequence: MSWQDYVDKQLMASRCVTKAAIAGHDGNVWAKSEGFEISKDEVAKIVAGFENESLLTSGGVTIAGTRYIYLSGTDHIIRAKLGKVGVHCMKTQQAVVISLYEEPIQPQQAASVVEKLGEYLITCGY
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MAK1_SCHPO
Sequence: MRPPDDQINNNVGSNSHLEKLKEAMDHQLQKSSKIVGSFTNSQNSSVGSVHSPILESPTSLNRQHRNSFSFNNVSSPSLEDERLINFPRVNPNRLMTSKRPNELFKTSSMSSDCYSPQKSRESLNSLCHSPAPSVSSCGNALNNDNTSASHSLTDEQPFETDSSANLFKQLQEKRNRTIGNVYEMACLLVFKTGLMNFWKNIIDFFAQQFFSTQISVVEPRDLSDIYNTPWQLRCYYDGGSHYDPYSNPISVNDNLASSSYVTVVASDGSKGIIYKDPASLKHEGDLLIDSKVVQTVLERATLLVYTRKQQHIVKNTKVHDNDYFSSIPNVDDIRSIKNSWKVFHDEKLNELKKQVEISASAAQLNGLYPQKKRAFVSHFSQNRKPYSQSDISKAQSSSFSEEPSNIYDEYEQNLLSPWSRSPVASPSIQTDPNRNPFFQNCLQESSFATESSTEKSASESVSETAVNDDCKGMNFSGNRRQEDHLNDFTSFPTETAVSIVHVPLMFPCSDQTSSRGRAPIAILSFKSNLVPYPENLIASIERLIPFIFSSYSNSQSVPLLPCPTQRHLLFNTSSTDNTKELSMSASSENSDCPHKEGECVGSFCNINAKGSSLNNIPKLPRFVPVPSEFFKKNQRSWVTLKKHRLLARLKSRISKKNSKVNENLRFSLNDGENYSNETITLKKDEIVLDKSKSYACCTSESHKYVQGHCGGQAPPFPLLKVIIDSIPVHVFTADPGSGKLTWVNRKTLLYCGLNMNEQIELQFSRIHPDDLPNFLNDWKSSLFSGSGFYHEIRLQRFDNVYRYFICRAVPLRDCTGSVLHFFGTMTDVHDQKLAERELQKQSAIAANENSYRSLAEASPQIVFAANGKNGIIYANAQWLSYSGLSLESSLGLGFLSAVYHADRKKCLLPESLEGTFNNQDESNGTKTFAAEIRFRSTDGHYRWHLVKSVCVNNSADTSTNLWLGTCTDIHDHKMLEEKLQESNIEAQRIVRSKMQYLSNMSHEIRTPLIGITGMVSFLLETQMSAEQLSYARIIQQSAKSLLTVINDILDLSKVRAGMMKLTSQRFSVRAMMEDANETLGTLAFSKGIELNYTVDIDVPDIVFGDNMRMRQVALNVIGNAIKFTNVGEVFTRCSVEKIDYSTNTVVLKWECIDTGQGFNRDDQLQMFKPFSQVESSTLPRHGGSGLGLVISKELVELHNGSMSCQSRRGVGTRFMWTATFTMDKTPLKFEPPDGCCPVCFCPYEKSKQSTEDYYCADDGNDKSATNFVKLAVNKADPGRESNRRKLESDKNVQSNKYVNPFASESEFCRCGASADPYTVLFWRLYRNKPSGIKLDKSALAVVVSHTKYSSEAIGNMLQSIIDISSFKDIVRYGNTYEAFEELLENPMQSKVTHIILNLPDIEAYVLFVKSLQLCSLYKDTKFILVTSTRQKESLSKIFSDSEDCNSESIHYVLKLVKPSKFFPLFYSDSEEKGKIGALNDMTRKAAMEQKADAETLRYNLAKSGFSVLLAEDNIINIKVISRYLERIGVKFKVTMDGLQCVEEWKREKPNFYSLILMDLQMPVMDGYQACNEIRKYELENDYPKVPIVALSANALPHVVLSCKDSGFDSYLAKPITLQHLSLIISGILNYTNQSKLHK
What is the function of this protein?
Involved in the control of the SAPK-dependent transcriptional response to peroxide stress.  Also has a role in G2/M regulation.
What are the official names of this protein?
Peroxide stress-activated histidine kinase mak1, His-Asp phosphorelay kinase phk3, Mcs4-associated kinase 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_WOLSU
Sequence: MEDKKIAMEETIRSIFDFIGDDRHREGLLDTPKRVVKSWDKLYSGYTQDPREILGTVFEDGACDEMVVLKNIEFYSMCEHHMLPFFGKVSIGYIPDQKVVGISKLARLVEVFARRLQIQEKMTGQIADTLMEVLQPKGAMVVAEATHMCMVMRGVEKQQSVMVTSAVRGLFKRDARTREEFMGHIRH
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: 2SS_JUGRE
Sequence: AALLVALLFVANAAAFRTTITTMEIDEDIDNPRRRGEGCREQIQRQQNLNHCQYYLRQQSRSGGYDEDNQRQHFRQCCQQLSQMDEQCQCEGLRQVVRRQQQQQGLRGEEMEEMVQSARDLPNECGISSQRCEIRRSWF
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
2S seed storage albumin protein, 2S albumin, 2S albumin seed storage protein, Allergen Jug r 1.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: NUOD_MYCMM
Sequence: MTDTETVLVAGGQDWNEIVEAARGADPGERIVVNMGPQHPSTHGVLRLILEIEGETVTEARCGIGYLHTGIEKNLEYRYWTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDEIPERVNVIRVMMMELNRISSHLVALATGGMELGAMTPMFVGFRAREIILSLFESITGLRMNSAYIRPGGVAQDLPPDGPTEIAKAIADLRQPLREMGDLLNENAIWKARTQDVGYLDLAGCMALGITGPILRSTGLPHDLRKSEPYCGYENYEFDVITADGCDAYGRYMIRVKEMWESIKIVEQCLDRLRPGPTMIEDRKLAWPADLKVGPDGMGNSPEHIAKIMGSSMEALIHHFKLVTEGIRVPAGQVYVAVESPRGELGVHMVSDGGTRPYRVHYRDPSFTNLQAVAAMSEGGMVADLITAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GBRB2_HUMAN
Sequence: MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKIFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
What is the function of this protein?
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:8264558, PubMed:19763268, PubMed:27789573, PubMed:29950725).  Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:23909897, PubMed:25489750).  The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity).  The alpha1/beta2/gamma2 receptor and the alpha2/beta2/gamma2 receptor exhibit synaptogenic activity (PubMed:23909897, PubMed:25489750).  Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
Protein: MRAY_WOLWR
Sequence: MILATKVFFTSFVFGFILFPYFIKLLKKISKDGQPIRSCGPESHLITKKNVPPMGGIIILTSSLLPILLWVQLTPEILLLILITLFFALLGFIDDYLKLKTNHYRGLSAKTKILIQFIVALVGVFILKLYSAECFTKTSLFKGVIIDFGYLYVPFAAFVIVGSSNAVNLTDGLDGLAATQVITSFAFLGLIAYITQADMNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSVGAALGLTSVLIKREMLFAVIGIIFVIETLSVIIQISYFKYTKFKYGEGKRVFLMAPMHHHFEKKGWSENVIVMKFWIISIICSVFTITFLL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACCD1_LACE2
Sequence: MNINDIFLKRKKRWGIINRLRDSEEQADGSLTPSRRIALISDDKSFRELYAQVKTGNPNSFPGYEQKVEANRLKTGQQDAVVTGTCRIGGVKTAVAVMDKRFLMGSMGIAVGEKITRLTEYAMKRKLPLIIFAASGGARMQEGLFSLMQMAKTTAAIEKFKDAGGLFISYLTNPTTGGVSASFASLGDIIIAEPGALICFAGPRVIEQTIGQKLPEGFQHSEFLLEHGMIDMIVDRKDMKQTLSKILKMHVNTGGEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 1, ACCase subunit beta 1, Acetyl-CoA carboxylase carboxyltransferase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFC6_YEAST
Sequence: MAVIPAKKRGRPRKSVVAEVPYDSLASPVSENSGSKRPRRNASKKAVANFAQLVHAGRDDVINTTQVNNVDDTDDDDFVLNDEGDGEESDNVEIEFENELESTKNEVADLNSSGSGASVRPSGRRNTVQKLRLKKNSTKNMKSSSPGSSLGQKGRPIRLLKDLSSARDKIERIYGLNKEKLLLLAKVKEGFETSVFDFPFKNIQPDSPYFVCLDPPCKKESAYNKVIGDKNRTVYHEINKTEFENMIKLRTKRLKLLIGEVDAEVSTGDKIEFPVLANGKRRGFIYNVGGLVTDIAWLNIEENTDIGKDIQYLAVAVSQYMDEPLNEHLEMFDKEKHSSCIQIFKMNTSTLHCVKVQTIVHSFGEVWDLKWHEGCHAPHLVGCLSFVSQEGTINFLEIIDNATDVHVFKMCEKPSLTLSLADSLITTFDFLSPTTVVCGFKNGFVAEFDLTDPEVPSFYDQVHDSYILSVSTAYSDFEDTVVSTVAVDGYFYIFNPKDIATTKTTVSRFRGSNLVPVVYCPQIYSYIYSDGASSLRAVPSRAAFAVHPLVSRETTITAIGVSRLHPMVLAGSADGSLIITNAARRLLHGIKNSSATQKSLRLWKWDYSIKDDKYRIDSSYEVYPLTVNDVSKAKIDAHGINITCTKWNETSAGGKCYAFSNSAGLLTLEYLS
What is the function of this protein?
TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements.  Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function.  Part of the tauB domain of TFIIIC that binds boxB DNA promoter sites of tRNA and similar genes.  Cooperates with TFC3 in DNA binding.
What are the official names of this protein?
Transcription factor tau 91 kDa subunit, TFIIIC 91 kDa subunit, Transcription factor C subunit 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y819_CHLTR
Sequence: MGLYDRDYAQDSRLPGTFSSRVYGWMTAGLAVTALTSLGLYATGAYRALFPMWWIWCFATLGVSFYIQAQIQKLSVPAVMGLFLAYSILEGMFFGTLVPVYAAQFGGGVVWAAFGSAGIIFGLSAAYGAFTKNDLTQIHRILMLALVGLVVISLAFLIVSLFTPMPLLYLLICYLGLIIFVGLTVVDAQSIRRVARSVGDHGDLSYKLSLIMALQMYCNVIMIFWYLLQIFASSDKRR
What are the official names of this protein?
Uncharacterized protein CT_819.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGC_RHORT
Sequence: MSERVNVAILGASGYTGAELVRLLARHPRVTLAALTANRKAGQAFASVFPHLGGLDLPVLSTIEAVDWSAIDFVFCALPHGTTQTIIGDLLNGPHGGRLRIADLSADFRLADPMVYQTWYGHAHEAVELQKEAVYGLTEINRAAIATARLVAVPGCYPTSAQLPLIPLLRAGLIDPDAIIIDAKSGASGAGRDAKEGSLHCEVSEGIHAYGVGTHRHGPEIEQGLSLAVGRPVAVTFTPHLMPMNRGILSTIYLRATAGNDATTLRQALSAAYADEAFVRVVPEGVSPHTRHVRGSNFVLIGVHADRVPGRVIVTCVEDNLVKGASGQAIQDMNVMLGFPETLGLDQQPLFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_SYNS9
Sequence: MIKLRLKRFGKKREASFRLVACNSTSRRDGRPLQELGFYNPRTKETRLDTEAIRERLGQGAQPTDIVRTLLERGGLIEKTVRPSVTVGQAKQTAKREAAAKQAAKDAAEAKAAAAAEAEAPAADAEASEG
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: HBD_CLOPA
Sequence: MKKVHVLGAGTMGAGI
What are the official names of this protein?
3-hydroxybutyryl-CoA dehydrogenase, Beta-hydroxybutyryl-CoA dehydrogenase, BHBD, CP 26.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: THAP5_HUMAN
Sequence: MPRYCAAICCKNRRGRNNKDRKLSFYPFPLHDKERLEKWLKNMKRDSWVPSKYQFLCSDHFTPDSLDIRWGIRYLKQTAVPTIFSLPEDNQGKDPSKKKSQKKNLEDEKEVCPKAKSEESFVLNETKKNIVNTDVPHQHPELLHSSSLVKPPAPKTGSIQNNMLTLNLVKQHTGKPESTLETSVNQDTGRGGFHTCFENLNSTTITLTTSNSESIHQSLETQEVLEVTTSHLANPNFTSNSMEIKSAQENPFLFSTINQTVEELNTNKESVIAIFVPAENSKPSVNSFISAQKETTEMEDTDIEDSLYKDVDYGTEVLQIEHSYCRQDINKEHLWQKVSKLHSKITLLELKEQQTLGRLKSLEALIRQLKQENWLSEENVKIIENHFTTYEVTMI
What is the function of this protein?
Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) (PubMed:21110952).  May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:19502560).
What are the official names of this protein?
THAP domain-containing protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSTS1_STRA5
Sequence: MKMKKNIFLLTLLATVLLTLSGCANWIDKGQSITSVGSTALQPLVEAAADEFGKTNLGKTINVQGGGSGTGLSQVQSGAVQIGNSDLFAEEKDGIDAKKLKDHQVAVAGLAVIVNKKVNVKNLTTHQLRDIFAGKIKNWKEVGGQDLDISIINRAASSGSRATFDNTIMGNVAPIQSQEQDSNGMVKSIVSQTPGAISYLAFAYVDKSVGTLKLNGFAPTAKNVTTDNWKLWSYEHMYTKGNETGLTKEFLDYMKSDKVQSSIVQHMGYISINDMKVVKDAEGKVTPK
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS 1, PBP 1.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: S39AC_BOVIN
Sequence: MCFWTKPSVSWVSLFLLLSLDPSTETEKPSTQDSSSTWSPGQLTEVLRVLSADDPRPLNHSRSLIRTLLEKTGCPRRTDGRQGDCNLCFEPDALLLIAGGDFEDQLKEEVIQRVSLLLLYYIIHQEEICSSKLNMSNKEYTFYLHSLLSLRQDEDSYFLSQNETEDILAFTRQYFDTSRNQCMETKVLQKKSGILSSDGADENTLPQLAATIIALSLQGVCLGQRNLPPPDYFTEYIFSALNSTNTLHLSELDKLLNTLWTKSTCIRKDKIHQLRRKQNSLTLHDGDYSNLSVSMDPESEDGPISWDQTCFSAGQLVNIFLQNKLSPISKEDFKQMSPGIIQQLLSCSCQLPQNQQAKIAPTTLEKYGYSTVAVTLLTLGSMLGTTLILFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQILGLHMQETSEFGHFYENKGHIWKLLGLIGGIHGFFLIEKCFTLLVSPGAKKGPEDAQAAEIPIPSVNTPNRKCKTISLLAIMILVGDSLHNFADGLVIGAAFSSSSEAGVTTTIAILCHEIPHEMGDFAVLLSSGLPVKIAILMNFISALTAFIGLYIGLSVSTDPCIQNWILTVTAGMFLYLSLVEMLPEMTHVQTQRPWLMFLLQNFGLTLGWLSLFLLAIYEQNIKI
What is the function of this protein?
Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane.  The transport activity is temperature dependent.  May play a role in neurulation and neurite extension.  May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis.
What are the official names of this protein?
Zinc transporter ZIP12, Solute carrier family 39 member 12, Zrt- and Irt-like protein 12, ZIP-12.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SLS_LEIMA
Sequence: MTSHVTAHDVGGNEDIGTDHVPWYKQPLPLCTQVMRFILLLLLTVMFLGVAILVANARMPDPEKVRPLPDLLLESIPKVALLENGTNVIIFLLNATTVVVGFKVFLLERHMNGLPRVTFLVGVPKIGSFLNRMAFGVLDSGRRPFPLKNVFPIMAIRFLTSYAVVMVFRAFVIMGTSYPATDNHCQNPQVIEHPVLNVILTLVTLGSGAIHCGDLMFSGHTMILSLAFILAWDYSPFLHPWAVRVWVSVLLPISYYCILASRSHYTDDILVAMYVMIATYKVIDHAETGAPWQMQLLIRWMPWPGANTIEKWTADEVVVVVQTPAEDSTDASAALPEH
What is the function of this protein?
Bidirectional lipid inositolphosphotransferase capable of converting phosphatidylinositol (PI) and ceramide to inositol-phosphorylceramide (IPC) and diacylglycerol (DAG) and vice versa.  Direction is dependent on the relative concentrations of DAG and ceramide as phosphoinositol acceptors.  Essential for viability of the pathogenic bloodstream stage of this human protozoan parasite and, consequently, can be considered as potential drug target.
What are the official names of this protein?
Phosphatidylinositol:ceramide inositolphosphotransferase, LmjIPCS, Inositol-phosphorylceramide synthase, IPC synthase, Sphingolipid synthase.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YCF24_GALSU
Sequence: NSEVKYSTVQNWYSGDENGKGGIYNFVTKRGLCAESNSKISWTQVETGSAITWKYPSCILAGNNSKGEFYSVALTNHYQQADTGSKMIHIGKNSRSKIISKGISTGNSINSYRGKVKVSLNASRARNYSQCDSLLIGNSSEANTFPYIEVYNRSSIIEHEASISKINEEKLFYFMQRGISIEEAISLIVSGFCKEVFTELPLEFALEADKLLGLKLEGSVG
What are the official names of this protein?
UPF0051 protein in atpA 3'region, ORF X.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YVZG_BACSU
Sequence: MKSIEDYTLLSAYYHLLFTIEEGLCYLIEAEENLSKTEGDRIYQDLIQAFFYLDSTHSTLLFIMDSRCAEICVKAFDQIFAEFDQLVSFSFPSHEFCEYLKEHFLIHYRKWMLSIHQCMEPFLIN
What are the official names of this protein?
Uncharacterized protein YvzG.
Protein: TRMD_LEGPH
Sequence: MALHLGVITLLPEIIQGIHYGVTGRAIEQGLVKIDCWNPRDWSSRPYKQVDDKPYGGGPGMVMMYEPLHAAIKHARSEMKENCKTIYLSPQGKVVRQNDLKQIAAQKQSLLFVAGRYEGIDERIISHHVDEEWSLGDFVLSGGELAAMVFIDAIIRLIPGSLGHLGSAEQDSFMNGLLDCPHYTRPATINGLDVPDVLLGGNHKEIERWRRKQSLGKTWLKRPDLLEKVQLSETDKQLLAEFKCEHGDSC
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.