PharMolix/UniProtQA huggingface dataset:
Protein: NRAM_I97A0
Sequence: MNPNQKIITIGSICMVVGIISLMLQIGNIISVWVSHIIQTWHPNQPEPCNQSINFYTEQAAASVTLAGNSSLCPISGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRTLMSCPVGEAPSPYKSRFESVAWSASACHDGISWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNEQASYKIFKIEKGRVVKSVELNAPNYHYEECSCYPDAGEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGVFGDSPRPNDGTGSCGPVSLNGAYGVKGFSFKYGNGVWIGRTKSTSSRSGFEMIWDPNGWTETDSSFSLKQDIIAITDWSGYSGSFIQHPELTGLNCMRPCFWVELIRGRPKEKTIWTSGSSISFCGVNSDTVGWSWPDGAELPFTIDK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: CRTP_STAAS
Sequence: MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNAILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGIPMVTLSGQQVADKINAREAKNRK
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes the oxidation of the terminal methyl side group of 4,4'-diaponeurosporene to form 4,4'-diaponeurosporen-4-al.
What are the official names of this protein?
4,4'-diaponeurosporene oxygenase, 4,4'-diaponeurosporene oxidase, Carotenoid oxidase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtP subfamily.
Protein: ERGI1_HUMAN
Sequence: MPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDSGGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKVPGNFHVSTHSATAQPQNPDMTHVIHKLSFGDTLQVQNIHGAFNALGGADRLTSNPLASHDYILKIVPTVYEDKSGKQRYSYQYTVANKEYVAYSHTGRIIPAIWFRYDLSPITVKYTERRQPLYRFITTICAIIGGTFTVAGILDSCIFTASEAWKKIQLGKMH
What is the function of this protein?
Possible role in transport between endoplasmic reticulum and Golgi.
What are the official names of this protein?
Endoplasmic reticulum-Golgi intermediate compartment protein 1, ER-Golgi intermediate compartment 32 kDa protein, ERGIC-32.
What is the protein family that this protein belongs to?
Belongs to the ERGIC family.
Protein: ACOHC_DICDI
Sequence: MTTNNPFDKVKDVLKSQDQTYNFYNLSKLQDPRIEKLPYSIRILLESAVRNCDNFEVHEKDVENILNWENTANKVEIPFKPARVLLQDFTGVPAVVDLAAMRDAMKRLGGDPAKINPLVPVDLVIDHSVQVDVSRTVDALEQNQKIEFHRNHERFSFLKWGAQAFDGLFIAPPGSGIVHQVNLEYIAREVMNGTGNLLYPDSVVGTDSHTTMINGLGVCGWGVGGIEAEAVMLGQPMSMVLPEVVGYKFVGKLPDIATATDLVLTVTNELRKKGVVGKFVEFYGEGVSTLSVQDRATISNMAPEYGATMGFFPADENTIDYLASTGRSNTKIEYIKNYLSSQGLMCNYKSQSHPIFTTTMELDLSTVVPSLSGPKRPHDRISLNSMKQDFNSCLSSPVGFKGFGLTADQIQKKATFTFKDKQYTIGHGAVTIAAITSCTNTSNPSVMLGAGLLAKNAVEHGLEVAPYIKTSLSPGSGVVTEYFSHSGLQEPLNKLGFDLTGYGCMTCIGNSGELAEPLAEAITKEDLVVAGVLSGNRNFEGRIHPLLRANYLASPPLVVAYALAGTVDIDFETTPLGVSKKTGQPVFLRDIWPSKDLIQQTIKSSVLPDMYERVYSNVNDGNKSWNELKVPTGLLYPWDEKSTYIHNPPFFKTMELTVSKRPAITNAYCLLNLGDSITTDHISPAGNINRKSSAARYLESKGVKPEDFNTYGSRRGNDEIMVRGTFANTRIVNKLAPAVGPQTTYVPTGELMFISDAAEKYQSEGHQLIVLAGSDYGSGSSRDWAAKGPYLQGIKCVIAISFERIHRSNLVGMGIIPLQFQPGQNASTLGLTGKEQFNIELPTDKSLIKTGQTVKVTTNCGKSFETILRFDTPIEVEYWANNGILSYVLRKLLH
What is the function of this protein?
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
What are the official names of this protein?
Probable cytoplasmic aconitate hydratase, Aconitase, Citrate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: FLGI_NITMU
Sequence: MRYPVSTGIAAPAWFAFFCAWAGLWTFSLPVQAERIKDLASIQGIRPNQLIGYGLVVGLDGTGDQTVQTPFTIQSLNNMLMQLGINVPPGTNMRLRNVAAVMVTAALPPLAQPGQAIDVTVSSMGNARSLRGGTLLMTPLKGIDGQVYGVAQGNLLVGGIGAAASGSKVQVNHLNAGRIPGGATVERAVPVALGQNDMIRLELNTIDFSTAKRIVDAVNTRFGMGTAAALDGRAIQVRTPPESDQRVAFLAEMESLAINPAQMPARVIVNSRTGSVVMNQAATVDQCAIAHGNLTVVISTEPVISQPGPFSSGRTVQAQRSTIEIKQESGMLTMVEGASLAEVVKALNAIGATPQDLLAILQAMKSAGALRAELEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: CYSN_ECOUT
Sequence: MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIHYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: RBSD_STACT
Sequence: MKKTPLLNSQVSQAVATIGHFDLLTINDAGMPIPNDERRIDLAVTKALPRFIDVLETVVTEMEIQKIYLAEEIKMHNPDQLKAIKGLIAEDVEIEFIPHSQMKEYLSHPLNKGNVRTGEITPFSNIILESNVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT_SPHSI
Sequence: MSKGKLSERISHFNIVEELKSKGLYAYFRPIQSKQDTEVMIDGKRVLMFGSNSYLGLTIDPRIIEAAQDALSKYGTGCAGSRFLNGTLDIHIELEHKLSQLVGKEASILFSTGFQSNLGPISCLMGRNDYILLDERDHASIIDGSRLSFSKVIKYGHNDMDDLRAKLSRLPSESAKLIVTDGIFSMEGDIVNLPEMVKIADEYDAALMVDDAHSLGVIGEHGAGTASHFGLTDKVDLIMGTFSKSLASLGGFVAGDADVIDYLKHNARSVMFSASMTPASVASTLKALEIMISEPEHMENLWKNTNYAKQQLLESGFDLGATESPILPIFIRNNEKTFWVTKMLQDDGVFVNPVVSPAVPSEESLIRFSLMATHTFDQIDEAVEKMVRVFKQAEIESLI
What is the function of this protein?
Catalyzes the condensation of L-serine with palmitoyl-CoA (hexadecanoyl-CoA) to produce 3-oxosphinganine.
What are the official names of this protein?
Serine palmitoyltransferase, SPT.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PS2_PSEPD
Sequence: GLNALKKVFQGIHEAIKLINNHVQ
What is the function of this protein?
Antimicrobial peptide with activity against fungus (C. albicans) and Gram-positive and Gram-negative bacteria (S. aureus and E. coli) (PubMed:11689009).  Also has low hemolytic activity against human erythrocytes (PubMed:11689009).
What are the official names of this protein?
Pseudin-2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Pseudin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NF2IP_MOUSE
Sequence: MAEPLRGRGPRSRGGRGARRARGARGRCPRARQSPARLIPDTVLVDLVSDSDEEVLEVADPVEVPVARLPAPAKPEQDSDSDSEGAAEGPAGAPRTLVRRRRRRLLDPGEAPVVPVYSGKVQSSLNLIPDNSSLLKLCPSEPEDEADLTNSGSSPSEDDALPSGSPWRKKLRKKCEKEEKKMEEFPDQDISPLPQPSSRNKSRKHTEALQKLREVNKRLQDLRSCLSPKQHQSPALQSTDDEVVLVEGPVLPQSSRLFTLKIRCRADLVRLPVRMSEPLQNVVDHMANHLGVSPNRILLLFGESELSPTATPSTLKLGVADIIDCVVLASSSEATETSQELRLRVQGKEKHQMLEISLSPDSPLKVLMSHYEEAMGLSGHKLSFFFDGTKLSGKELPADLGLESGDLIEVWG
What is the function of this protein?
In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2.  Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression.  Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
What are the official names of this protein?
NFATC2-interacting protein, 45 kDa NF-AT-interacting protein, 45 kDa NFAT-interacting protein, Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.
Protein: PUR7_MYCS2
Sequence: MRPALSDYQHLASGKVREIYRIDDEHLLFVASDRISAYDYILDSQIPDKGRILTAMSVFFFDHLLRTAGVPNHLAGPPDDERIPADVLGRALVVRRLDMLPVECVARGYLTGSGLIDYEKTGTVCGIALPPGLGEASKFDEPLFTPATKAEIGEHDENISFAKVIELVGAELANQLRDRTLQTYTAGADHALSKGIIIADTKFEFGVDRDGTVVLADEVFTPDSSRYWRADSYQPGVVQNSFDKQFVRNWLTGPESGWDRHGNTPPPALPDDIVAATRERYIEAYERISGLSFDDWIGA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SPSD_BACSU
Sequence: MYTVKENVSKEAIEEFLQSRKLTLDVPYQFSLGLFENSRLQGVLLYEDSLWESKVLQKKVMNVKLLAANSTGQLKRLFEAFYTVRQMDETDFIFVRVPAEDIGAAHVIQQQPSSYFVGSLLKLAMPPSFYDKTPPFFELGPPEPGDTEAICELARDSFTKSRYFQDPHLSRDAANEIFQEWTRNNLNGRAAVNIVAKHNGEVIGYLQGLSRDDECILDLMAVKPGFEGKRIAFHLLANLIEQPETQKHRTVTAGTQLHNVRAIRLYERMGFTAEQSYYYYHIWPGKEAK
What are the official names of this protein?
Spore coat polysaccharide biosynthesis protein SpsD.
Protein: XGPT_RUEST
Sequence: MSTKDPNRLPHEKGFHISWDQIHRDSRALAWRLDGLGPDDGHWRAVVAITRGGMAPAMIVARELDIRTVDTISVKSYHSGGGKADQRREAEVLKSPDADIMGDGTGILIVDDLVDSGKTLELVRTLYPKAHFATVYAKPQGEPQVDTFITGVSQDTWIFFPWDMALQYVEPYRGTD
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DEOB_SALHS
Sequence: MKRAFIMVLDSFGIGATEDADRFGDVGSDTLGHIAEACAKGEADNGRKGPLNLPNLTRLGLVKAHEGSTGKIAAGMDGNADVIGAYAWAHELSSGKDTPSGHWEIAGVPVLFDWGYFSDHENSFPQELLDKLVKRANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTEGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKQGHVVSVGKIADIYANCGITKKVKATGLDALFDATLKEMKEAGDKTIVFTNFVDFDSSWGHRRDIAGYAAGLELFDRRLPELMELVGEDDILILTADHGCDPSWTGTDHTREHIPVLIYGPKVKPGSLGHRETFADIGQTLATYFGTSPMDYGKNML
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUT1_CAEEL
Sequence: MTWKPIICLAALVLSASAIPVDNNVEGEPEVECGPNSITVNFNTRNPFEGHVYVKGLYDQAGCRSDEGGRQVAGIELPFDSCNTARTRSLNPKGVFVSTTVVISFHPQFVTKVDRAYRIQCFYMESDKTVSTQIEVSDLTTAFQTQVVPMPVCKYEILDGGPSGQPIQFATIGQQVYHKWTCDSETTDTFCAVVHSCTVDDGNGDTVQILNEEGCALDKFLLNNLEYPTDLMAGQEAHVYKYADRSQLFYQCQISITIKDPGSECARPTCSEPQGFGAVKQAGAGGAHAAAAPQAGVEEVQAAPVAAAAPVAAPVAAAAAAPAVPRATLAQLRLLRKKRSFGENEGILDVRVEINTLDIMEGASPSAPEAAALVSEESVRRRATSTGICLTPIGFASFLGIGTIVATALSATIFYVARPTSHKH
What is the function of this protein?
Component of the cuticles, which contributes to the formation of extracellular envelopes protecting the organism from the environment (PubMed:1864469) (Probable).  Plays a role in alae formation in dauer larvae (PubMed:15936343, PubMed:30409788).
What are the official names of this protein?
Cuticlin-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted.
Protein: VIRB5_BRUA2
Sequence: MKKIILSFAFALTVTSTAHAQLPVTDAGSIAQNLANHLEQMVKFAQQIEQLKQQFEQQKMQFDALTGNRGLGDILRDPTLRSYLPHNWRDLYEAVMSGGYLAAAGETANLLRKSQVYDPCASISDKDQRIACEAKVVKPVQDKVMTSKAYDATDKRLQEIESLMQEINKTGDPKAIAELQGRIESENAMIQNEDTRLRLYQQMAEAQDKLLDERQHELDAKDNARRGYPQPKALEAAY
What is the function of this protein?
The virB operon is essential for intracellular survival and is not involved in the invasion process.  Constitutes a major determinant of virulence in mice.
What are the official names of this protein?
Type IV secretion system protein virB5.
What is the protein family that this protein belongs to?
Belongs to the virb5 family.
Protein: NU4C_CUCSA
Sequence: MNYFPWLTTVVVFPIFAGLLLFFFPHRGNKVMRWYTICICVLELLLTTYAFCYHFELDDPLIQLMEDYKWIPFLDFYWRLGIDGLSIGPILLTGFITTLATLAAWPVTRDSRLFYFLMLAMYSGQIGSFSARDLLLFFIMWEFELIPVYLLLSMWGGKKRLYSATKFILYTAGGSIFLLMGVLGIGLYGSNEPTLNFETSANQSYPIALEILFYIGFLIAFAVKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSIFSPWLIIVGIIQIIYAASTSSGQRNLKKRIAYSSVSHMGFIIIGIGSISDTGLNGAILQIISHGFIGAALFFLAGTSYDRIRLVYLDEMGGLAIPIPKIFTTFSILSMASLALPGMSGFVAELIVFFGIITSQKYLLMTKMVITLVMAIGIILTPIYLLSMLRQMFYGYKLFNAKNSYFFDSGPRELFVAISILIPVIGIGIYPDFVFSLSVDKVEAILSNYFAR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NS1_I83A5
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATSAGKQIVERILEEESDEALKMTIASVPVSRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIRMDQAIMDKKIILKANFSVIFGRLETLILLRAFTEEGAIVGEISPLPSLPGHTDEDVKNAIGVLIGGLKWNDNTVRVSEALQRFAWKGSNENGRPPLPSK
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: BTRF1_EBVG
Sequence: MLKCKQPGARFIHGAVHLPSGQIVFHTIHSPTLASALGLPGENVPIPALFRASGLNVRESLPMTNMRAPIISLARLILAPNPYILEGQLTVGMTQDNGIPVLFARPVIEVKSGPESNIKASSQLMIAEDSCLNQIAPFSASEHPAFSMVESVKRVRVDEGANTRRTIRDILEIPVTVLSSLQLSPTKSILKKAPEPPPPEPQATFDATPYARIFYDIGRQVPKLGNAPAAQVSNVLIANRSHNSLRLVPNPDLLPLQHLYLKHVVLKSLNLENIVQDFEAIFTSPSDTISEAETKAFEKLVEQAKNTVENIVFCLNSICSTSTLPDVVPDVNNPNISLALEKYFLMFPPSGTIMRNVRFATPIVRLLCQGAELGTMAQFLGKYIKVKKETGMYTLVKLYYLLRI
What are the official names of this protein?
Uncharacterized protein BTRF1.
What is the protein family that this protein belongs to?
Belongs to the lymphocryptovirus BTRF1 family.
Protein: FTN_STAAR
Sequence: MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEEAMFETHINYLTRIGDDSNALYLYEKELGTRTFDEE
What is the function of this protein?
Iron-storage protein.
What are the official names of this protein?
Bacterial non-heme ferritin.
What is the protein family that this protein belongs to?
Belongs to the ferritin family. Prokaryotic subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD6_METAC
Sequence: MLIGLTGTPGTGKTSVSKLLEKKRQWKIIHLNELIKEEHLYTEVDEKRDSVVADMELVRSRLPELINEMEKEPANKVVILESHLAHYITDIVIVLRAYPPELKKRLEKRGYSEEKVNENAEAESIDLILAEAFEWCDKVFEINTTGRTAEETAGDVEKIIDSLLSGKEEQLQEYGPGSLDWIDSVP
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
What are the official names of this protein?
Putative adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
Protein: DHOM_CORGL
Sequence: MTSASAPSFNPGKGPGSAVGIALLGFGTVGTEVMRLMTEYGDELAHRIGGPLEVRGIAVSDISKPREGVAPELLTEDAFALIEREDVDIVVEVIGGIEYPREVVLAALKAGKSVVTANKALVAAHSAELADAAEAANVDLYFEAAVAGAIPVVGPLRRSLAGDQIQSVMGIVNGTTNFILDAMDSTGADYADSLAEATRLGYAEADPTADVEGHDAASKAAILASIAFHTRVTADDVYCEGISNISAADIEAAQQAGHTIKLLAICEKFTNKEGKSAISARVHPTLLPVSHPLASVNKSFNAIFVEAEAAGRLMFYGNGAGGAPTASAVLGDVVGAARNKVHGGRAPGESTYANLPIADFGETTTRYHLDMDVEDRVGVLAELASLFSEQGISLRTIRQEERDDDARLIVVTHSALESDLSRTVELLKAKPVVKAINSVIRLERD
What are the official names of this protein?
Homoserine dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the homoserine dehydrogenase family.
Protein: MPPE1_CAEEL
Sequence: MIWLKNLRVPILLAIILVVYNEYFIFFIAFSSCQWPCKYGRCSESSVKAFMISDTHLLGKINGHWLDKLKREWQMYQSFWISTWIHSPDVTFFLGDLMDEGKWAGRPVFEAYAERFKKLFGDNEKVITLAGNHDLGFHYAIMPETLEMFKKEFRRGLIDEMKIKKHRFVLINSMAMHGDGCRLCHEAELILEKIKSRNPKNRPIVLQHFPLYRKSDAECDQVDEQHEIDLKEMYREQWDTLSKESSLQIIDSLNPKAVFGGHTHKMCKKKWNKTGNSEYFYEYTVNSFSWRNGDVPAMLLVVIDGDNVLVSSCRLPSEILQIMVYIFGGIGIVILAFILISRRVRIFKRRPSYSLLMYRSQEKCD
What is the function of this protein?
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi.  Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
What are the official names of this protein?
Metallophosphoesterase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. MPPE1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis- Golgi network membrane; Multi-pass membrane protein.
Protein: PPK4_DEREJ
Sequence: DHLPHDVYSPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Pyrokinin-4, YXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LNT_PASMU
Sequence: MLHYLKKMKKKIFTYFIAIFSGIIGVLAFSPFDYWGCAYLSLLGLIFVAKTAEKKTALWSAFLWGLAFFTFGINWVHVSIHQFGGASVVVSYVLVLVLAAYLALYPMLFAYLIQRFQISSLAMFPVIWTFTEFLRGWLFTGFPWLQFGYSQIDSPFAHLAPMFGVTGVTFFVMWVSAVIFNLLSVLLIKPRKWNVVIANLLLLTLVGGLSAYSSKAEYVRKIEDRDLLVTLAQGNIEQNLKWEPEYLYQTLDIYHKLISQHLGKTDVIILPESALPVLENHIQPFFQGLQAHAQQAGTEIVMGTIYQDKTANKLLNSIITLGNTDFPYSLETTNRYSKHHLVPFGEYVPLETLLRPLGSVFNLPMSAFQSGDEIQSPLVVKNRQLSAAICYEIILGEQLRKNVKQDTDFILTVSNDAWFGDSIGPWQHLQMARMRALEFGKPVIRATNTGISVFIDEQGKIVAQAPQFIETTLTHKVAATEGQTPYAVFGNTAIYGLSLLLLLMRGFGALIRRRLFMPRL
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL29_GEOMG
Sequence: MKASDLKNMSVEELTAKNVELTKELFNLRFQLHTGRLENTAKISAVKKDIARVNTFLSERRG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: LAP_MYXVL
Sequence: MATVVNMDTVVNLDDVSLADKCCWICKEACDIVPNYCKCRGDNKIVHKECLEEWINTDVVKNKSCAICESPYNLKRRYKKITKWRCYKRDCHDSLLVNMSLCLIVGGMGGYLLISTEIVKLIASEEVSNIAKVFLVSASMGPFMVSALTMVRACIDCRTYFIATRERNTIHEVAEMEDVEEVEEVNDDDGDEYVDAVEEIVVESPA
What is the function of this protein?
E3 ubiquitin-protein ligase which promotes ubiquitination and subsequent degradation of host MHC-I and CD4 molecules, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.  Binds target molecules through transmembrane interaction.  The result of this ubiquitination is the enhancement of the endocytosis of the target chain and the delivery to the lysosome, where it is proteolytically destroyed (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase LAP, Leukemia associated protein, LAP, RING-type E3 ubiquitin transferase LAP.
What is the protein family that this protein belongs to?
Belongs to the poxviridae LAP protein family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network membrane. Host early endosome membrane.