PharMolix/UniProtQA huggingface dataset:
Protein: MUTS_NITEC
Sequence: MTTSGNSINKPDHSAHTPMMQQYLRIKTQHTDKLLFYRMGDFYELFYEDAEKAARLLDITLTHRGSSAGEPIKMAGVPFHAADQYLAKLVKLGESIAICEQIGDPATSKGPVERQVVRIITPGTLTDAGLLEERGNSIVLTLALHHGVIGLAWLNLAAGDMRVLETSPDNLASELERLHPSEILLPESLALPVILNSFTAPKRLPDWQFDYEHAMQQLTRQFGTRDLNAFGCEELRAAIMAAGALFEYVRLTQHTATDESATQVLGHLQTLRVERPETYLRMDAATRRNLEITLTLRGEEAPTLSSLLDICATSMGSRLLRHWLHHPLRNRITLQQRLDAVSDLIGAKPGILYAGIRERLKHIADIERITSRIALRTARPRDLSGLRDSLTALPEIIKLITTSTAIAIHRFVPAMEPDTTLTQLLVHALQPVPGAVIREGGVIADGYDAELDELRALQKNCGEFLLQLEARERERTGIPTLKVEYNRVHGFYIEVTRIHGEKIPADYRRRQTLKNAERYSIPELQVFENKTLTAREQALAQEKKLYEQLLEQLADFIIPLQEIARSVAELDVLCAFAERADLFGYTKPVFTDDPALDIEAGRHPVVENQIEQYIANDIQLGAVTREGRQMLIITGPNMGGKSTYMRQTALIILLAHCGSFVPAGSARIGPIDQIFTRIGAADDLAGGRSTFMVEMTEAASILRNATAQSLVLVDEIGRGTSTFDGLALAFAIARHLLTQNQSYTLFATHYFELTRLAEEFPQAINVHVTAVEHKRRIVFLHRIEEGSASRSYGLHVAALAGVPDKVIRNAGKILAQLEQEALSKSPQQTLFETIEENAEAAPASAHPVLDYLEQLHPDELTPREALEQLYLIKSMANRIK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CND2_YEAST
Sequence: MTTQLRYENNDDDERVEYNLFTNRSTMMANFEEWIKMATDNKINSRNSWNFALIDYFYDLDVLKDGENNINFQKASATLDGCIKIYSSRVDSVTTETGKLLSGLAQRKTNGASNGDDSNGGNGEGLGGDSDEANIEIDPLTGMPISNDPDVNNTRRRVYNRVLETTLVEFETIKMKELDQELIIDPLFKKALVDFDEGGAKSLLLNTLNIDNTARVIFDASIKDTQNVGQGKLQRKEEELIERDSLVDDENEPSQSLISTRNDSTVNDSVISAPSMEDEILSLGMDFIKFDQIAVCEISGSIEQLRNVVEDINQAKDFIENVNNRFDNFLTEEELQAAVPDNAEDDSDGFDMGMQQELCYPDENHDNTSHDEQDDDNVNSTTGSIFEKDLMAYFDENLNRNWRGREHWKVRNFKKANLVNKESDLLEETRTTIGDTTDKNTTDDKSMDTKKKHKQKKVLEIDFFKTDDSFEDKVFASKGRTKIDMPIKNRKNDTHYLLPDDFHFSTDRITRLFIKPGQKMSLFSHRKHTRGDVSSGLFEKSTVSANHSNNDIPTIADEHFWADNYERKEQEEKEKEQSKEVGDVVGGALDNPFEDDMDGVDFNQAFEGTDDNEEASVKLDLQDDEDHKFPIRENKVTYSRVSKKVDVRRLKKNVWRSINNLIQEHDSRKNREQSSNDSETHTEDESTKELKFSDIIQGISKMYSDDTLKDISTSFCFICLLHLANEHGLQITHTENYNDLIVNYEDLATTQAAS
What is the function of this protein?
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.  The condensin complex probably also plays a role during interphase.
What are the official names of this protein?
Condensin complex subunit 2, Barren homolog, CAPH homolog.
What is the protein family that this protein belongs to?
Belongs to the CND2 (condensin subunit 2) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Protein: TNP5_ECOLX
Sequence: MPRRQILSSEEQERLLVIPDDEIILTRMCFLNEQDIALINKHRRPANRLGFAVLLCYLRGPGFIPDKSNVPHSSVISRIASRLKLQPDLWPEYASREQTRWEHLTELYRYLKLSPFSRSLQKDCIRHLHPYAMRTDKGFMLAEEMLNWLHSNNVIFPSVDVIERTLAEAVTLADRAVFSALTAQLEKQHKSALDSLLKSEGEQASRLAWLLQPPGKINGKNVLQHIDRLNSIAALGLPDGITLSIHQNRLLKLAREGRKMSSRDLAKFTDVRRYATLVCVIQEAQATLTDEVIELHERILGTLFSRAKRTQAERLQLTGKLIQSKLKQYVTVGQALLHARESGEDPWAAIEDVLPWQEFINSLEETQFLSRKGNFDPLHLITEKYSTLRKYAPRMLSALQFIATPPAQTLSDALDTIRDMYRKQLRKVPPAAPTGFIPESWRKLVLTPSGIDRKYYEFCVMNELKGALRSGDIWVKGSRRYRNFDDYLIPAAEFEKSRHNDQLQLAVQTDCRAYLQARMTLLASRLEEVNAMALAGDLPDVDISDKGVKITPLENSVPSGASPFADLVYGMLPHPKITEILEEVDNWTGFTRHFAHLKNNNVRPKDGRLLLTTILADGINLGLTKMAESCPGATKSSLEGIQAWYIRDETYSAALAELVNAQKARPLAAFWGDGTTSSSDGQNFRVGSHGRYAGQVNLKYGQEPGVQIYTHISDQYSPFYAKVISRVRDSTHVLDGLLYHESDLEITEHYTDTAGFTEHVFALMHLLGFAFAPRIRDLHDKRLFIHGKAERYPGLQSVISTTSLNIKDIEAHWDEILRLAASIKQGTVTASLMIKKLASYPKQNGLAKALREIGRIERTLFMLDWFRDPGLRRRVQAGLNKGEARNALARAVFMHRLGEIRDRGLENQSYRASGLTLLTAAITLWNTVYIERAIESLKRKGIPINNQLVSHLSPLGWEHINLSGDYVWRNNIKLGSGKYRSLRTVDTELYKKQS
What is the function of this protein?
Required for transposition of transposon Tn2501.
What are the official names of this protein?
Transposase for transposon Tn2501.
What is the protein family that this protein belongs to?
Belongs to the transposase 7 family.
Protein: PRA10_HUMAN
Sequence: MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLCS
What are the official names of this protein?
PRAME family member 10.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
Protein: Y912_METMA
Sequence: MPITSNEISVEVNGQVYTLPAGSTLGDALKVSRAPYIAGAAIGILKKAAEKRTEKITEYAINTPKGELRIEIKDPESTSGKLWAEHYKEYEGKDIHWESPEALAFGPFEADIKPSRETGNFEAFDVLFGAGGFDPHNTHLILSRKRHSAEYGSPDDGVFASIVTGRKIISKISKEDSILSIEPVIEWERITEKTCTTDLSTPLEDEDSVYTYFEVELSRNAPVGAEHFYALTREGTLKVDAVTSSFISDDSLREVPAPYENFEQRREGAISVRTVGYGTGRIYISREERPSSLVHSVVGQVTKGLELIKLAEKGQKLSVESLPPQIVLLGHSFEEVEPLLSSIGVELIKEGYAGENSVIVRQEPPTTLEILGEAKVKAYAVARTKLIEVELYTEIAPKSIDFFRHALDLKTKTVGKLPVHMIYETTYLFKTEKEMVKYKEILPENTPEKKVLAGEIGITNQAAKRMGTIGVRLIDDDLFGPTGEKFSSTNIIGRIVEPDRLKGIKEGDAIYITEVARKENGGQKN
What are the official names of this protein?
UPF0288 protein MM_0912.
What is the protein family that this protein belongs to?
Belongs to the UPF0288 family.
Protein: UBC9A_DANRE
Sequence: MSGIALSRLAQERKAWRKDHPFGFVAVPMKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFSPS
What is the function of this protein?
Accepts the ubiquitin-like proteins sumo1, sumo2 and sumo3 from the uble1a-uble1b E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as ranbp2 or cbx4.  Essential for nuclear architecture and chromosome segregation (By similarity).  Mediates nuclear localization of vsx1.  Required for progression through mitosis during organogenesis.
What are the official names of this protein?
SUMO-conjugating enzyme UBC9-A, RING-type E3 SUMO transferase UBC9-A, SUMO-protein ligase A, Ubiquitin carrier protein 9-A, Ubiquitin carrier protein I-A, Ubiquitin-conjugating enzyme E2 I-A, Ubiquitin-protein ligase I-A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1934_STRMU
Sequence: MKPFIEFKDFSFKYDAQAEPTLKEITLSIEKGEKVLIIGPSGSGKSTIGHCLNGIIPNIYKGQAEGSLTIDGKDVFDLSIYEKSHLVSTVLQDPDGQFIGLTVAEDLAFALENDCVAHETMFERVDTWADKLDLKELLQHRPQDLSGGQKQRVSLAGVMIDESPVLLFDEPLANLDPKSGQDTIDLIDHLHQTAETTTIIIEHRLEDVLYRPVDRVILINEGQVLFNGSPNDLLKTSLLQENGIREPLYVTVLRHLGLDIKNTSHLANLEQLDLSGVSFAGDISLKEPQEPQVLFDIQHLNFAYSSERPILKNLSFTLNKGERLAIVGKNGAGKSTLAKALCQFISYAGQIFYQGQDIASDSIKERSERIGYVLQNPNQMISQTMIFDEVALGLRLRGVDDSQIEKRVLKVLKTCGLYEFRKWPISALSFGQKKRVTIASILVLNPEVILLDEPTAGQDKKHYTEMMSFLNDLHALGHTIIMITHDMQLMLEYSDRALVISDGQILADQSPITLFNQPDILRIANLKQTSIFDLAQRLNCDPIALTHYYIDQQGGEDE
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein SMU_1934c.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TPIS_DELAS
Sequence: MKKKLIVGNWKMNGGLAANAVLLKALKEGLPEGGNAGVAVAVPAVYLAQAQAELEGSAIGVAAQDVSQHESGAYTGELSAAMLRDFGVRYTLVGHSERRQYHGETDAVVALKAQAALAKGVTPIVCVGETLAEREAGQTEEVVKRQLAAVIHQVGQCINELVVAYEPVWAIGTGRTATPEQAQQVHAVLRAQLAAASQQADRIALLYGGSMNASNAAQLLAQADIDGGLVGGASLKAADFLTIIAAAQ
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX20A_PHORI
Sequence: ACAGLYKKCGKGVNTCCENRPCKCDLAMGNCICKKKFVEFFGG
What is the function of this protein?
Inhibits high-voltage activated calcium channels.  Shifts the voltage-dependence for activation towards hyperpolarized membrane potentials for L- (Cav1), P/Q- (Cav2. 1/CACNA1A) and R-type (Cav2. 3/CACNA1E) calcium currents.  Causes immediate agitation and clockwise gyration, followed by the gradual development of general flaccid paralysis when injected intracerebroventricular into mice at dose levels of 5 ug per mouse.
What are the official names of this protein?
Omega-ctenitoxin-Pr1a, Omega-CNTX-Pr1a, Neurotoxin PRTx17C3, Neurotoxin PRTx3-7, Tx3-7.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family.
Protein: KTHY_THEVB
Sequence: MHSATHPYAGLFIVLEGGEGAGKTTQMGAIATWLENSGWLAKLRSCHVDPPLLLTREPGGTPLGQGLRQLLLHSDLAIDPLAELLLYAADRAQHVAMGIRPQLQRGGIVLCDRYTASTVAYQGYGRGLDLQIIQHINQMATGGLGADLVLWLDLPVAVGLARTQQRGRGDRLEQNAVAFHERVRQGFLALAQQGSDRWQRIDADQPPDQVTQAIQECLAAHLHRWFETLKQRLTGGDRDLP
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RUVA_HELPS
Sequence: MIVGLIGVVEKISALEAHIEVQGVVYGVQVSMRTSALLQAGQKARLKILQVIKEDAHLLYGFLEESEKILFERLLKINGVGGRIALAILSSFSPNEFESIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDETKPMHNEVFLALESLGFKSAEINKVLKTLKPHLSTEAAIKEALQQLRS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: AROE_SALSV
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFINTLDAFFAAGGKGANITVPFKEEAFARSDELTERASLAGAVNTLKRLEDGRLLGDNTDGIGLLSDLKRLNFIRPGWRILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAKIFAHTGSVHATDMDKLHGCEFDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKGNTPFLSWCVQQGAKRYADGLGMLVGQAAHAVLLWHGVLPQVEPVIELLQQELLA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: HSC90_DICDI
Sequence: MAESQVERFTFQAEINQLMSLIINTFYSNKEVFLRELISNASDALDKIRYQSLTDASVLESKTELEIKIIPDKTAKTLTLIDSGIGMTKTDMVKNLGTIARSGTKNFMEQLQSGAADISMIGQFGVGFYSAYLVADTVIVHSKNNDDEQYVWESSAGGEFTIALDHTEPLGRGTKIVLHMKEDQLDYLDETKIKNLVKKHSEFIQYPISLLTIKEKEVDEETTAKEGEEESTDAKIEEIEEEKEKKKVKVQEKEWDVLNKTKPLWTRNPSDVTKEEYNSFYKSISNDWEEPLAVKHFSVEGQLEFKAILFVPKKAPFDLFESKKKANNIKLYVKRVFIMDNCADIIPEYLNFVRGIVDSEDLPLNISRETLQQNKILTVIRKNLVKKCIELFNEIAENSEDYKKFYEAFSKNLKLGVHEDSQNREKFADLLRYQTSKSGDELVTLKEYVGRMKEGQNEIYYITGESKKAVENSPFIEGLKKKNLEVIYMCDPIDEYAVQQLKEYDGKKLVSITKEGLKLDETEDEKKKAEQDKAANEELLKQVKDVLGDKVEKVVLSTRLANSPCVLVTSEYGWSANMERIMKAQALRDSSMSSYMSSKKTLELNPDHPIVRDLAKKAAEKSKTFKDFVYLLYETALLTSGFSLDEPSSFASRIHRMIKLGLSIQDDSSATTEESTNTTTSDDIPPLEENDEPSEMEKVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock cognate 90 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM11G_MOUSE
Sequence: MYQPGILVRRKRVWKPWTVALITVALLLALAVLIGLLVYFLVYDEKTHYYQASFWIPSINYSSDLSKEQSKFRTGLKQKISNEIDVIFQRSSLKHHYVKSQVVNFRPSNDGVKADVLIKFQIPRKNAGTLKRQADNILQEKLQSSQSILKRDASLPYLREMNAAQAEHILNSDCGSGMEYPPIARIADGKPADKASWPWQSSLQVEGIHLCGASLIGSQWLVTSAHCFDNYKNPKLWTVSFGRTLSSPLTTRKVESIIVHENYASHKHDDDIAVVKLSSPVLFSENLHRVCLPDATFQVLPKSKVFVTGWGALKANGPFPNSLQEVEIEIISNDVCNQVNVYGGAISSGMICAGFLTGKLDACEGDSGGPLVISDNRNKWYLLGIVSWGIDCGKENKPGIYTRVTHYRDWIKSKTSI
What are the official names of this protein?
Transmembrane protease serine 11G, Serine protease DESC4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: PK1L2_MOUSE
Sequence: MAGLVFLGLALSSGATVAKSEGGSLCSRSQVFFRDACYEFVPLEHTFPGAQGWCEGHGGHLAFIPDEDTQQFLQRHITQDREWWIGLTGGSGHNGTVGGSGTWLDTSNVNYSNWQEGQATPAPGSCGYIGSGPSSQWAALEDCTQTFAFVCEFGVGRSLACEGHNATMHCDSGEVILVQDAFYGHQTPYLCTRGIWPPSDLEGECGWVSVKDEVAGQCQGLQACQVAVDGTYFGDPCPTRGSYLWVQYQCLEGLRLVVPNGSFIFDNVTISLMWLLSPYTGNLSCVLSMGDGYTFDPYNPPSVSSNVTHQFSSPGEFTVFAECTTSEWHVTAQKQVILCEKVETPRITGCTGLAGAGVGLLCQAVFGEPLWVQVDLDGGAGATYAVLSHNRTLAEFTAQRGSQLYNLTLDRDIQEMLGPGRHHLKIQAVSNEGTGTASAPSGNFTVYFVEPLSGLRASWASDRVELGWDLVVNVSVARGTLEELTFEVAGLNANFSQEEESVGQSSGNYHVAVPAEGTFLVTVHVRNAFSELSLDIGNITVTASSSLQELSGINAEAKSGHKQDMKVFTEPELYVDPFTEVTLGWPDDDPGLNFHWSCGRCWAQWNACVGRQLLHTDQRLLVLHTFCLPPLNSAVTLHLAILRGQELEKETEQCLYVSAPLNLGPQISCEKNCRPVKADQDVLLTVTVGDETSVAVFSWYLDDTVPEEVEPLPAACRLRGFWPRSLTLLHSNSSVLLLNSSFLQTWGPVIPIRVTALTSHAYGEDTYMISMLPRPEVPACTIDPEEGSVLTSFTVSCSTPATLGPVEYCFCLPSGFCLHCGPEPALPAVYLPLGEEKDGFVLPVVISVTNRAGDIEQTQVAVKVGHSYTGVEDVTFQEMVSERIATALHQESGREQLLLFAKAVSSELNSEVQSPGSGQLGMDIKRKVRELMLRSLSVVTTGLQNMQRVQALAEVLREVTQRAEELTPAAQWEASCALQRATEALLVASTKVRPEDQRRQEATRAMFEAVGSVLEASLSHRSEEPMEANSSQVAYIVAQLLRVIDHFQSALLLGTLPGGLPAILVTPSISVYTDRIQPRSWQGSSVHTAAADSVTFTLPAATFLCPMEDSQEPVDIRMMSFSQNPFPSRSQFDVSGTVGGLRLTSSSGHPIPVKNLSQNIEILLPRISAHIEPKMLSLASREALSVNVTAGDTALGIQLHWGPGVPLILSLGYGYHPNETSYDAQTHLPPVAATGDLPTWILHPEDLPFGEGVYYLRVVPEADLESSSGRNLTVGITTFLAHCVFWDETQETWDDSGCQVGPRTTPSQTHCLCNHLTFFGSSFLVMPNAIDVRQTAELFATFEDNPVVVTTVGCLCMLYVLVLIWARRKDIQDQAKVKVVVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTLTLYGSDGESEPHHLSDPDAAVFERGGVDVFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDSVVDRKWYFLCNSWLSVDVGDCVLDKVFPVATEQDRKQFSHLFFTKTSTGFQDGHIWYSVFCSATRSSFTRVQRVSCCFSMLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFRNTRPRLPMGKDGRQKQGPPNLTPSAQPTEEGLLTPETGIQSLISSLFKALKVQPPASGWDSMNPVDINYLLTLMEDIICPESTEGPGFWEEAKGREDPITSTRGSVKPKENTWHPKPELAVRGLWKDSVYRRCLYLQLEHVERELQLLGPQGFLHHHSHAQALRQLHVLKGHLWGQPGTPALAYPSTSRVSKSPRGLPWWCVLVGWLLVATTSGVAAFFTMLYGLHYGRVSSLKWLISMAVSFVESVFITQPLKVLGFAAFFALVLKREDDEETLPLFPGHLSSPGPGVLFRSRRHSSERAYQPPPMAAIEKMKTTRLKEQKAFALIREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSFSQGFSPVLGFRGFFEWANTTLVKNLYGHHPGFVTDGNSKLVGSAHIRQVRVRESSCAVAQQLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLETSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHREGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVILVAFSEEQKSDQLSEEGEIADLLLVKILSFLGIRCKREETWSSSEQPELPPQALAPQPAQALSRV
What is the function of this protein?
May function as an ion-channel regulator.  May function as a G-protein-coupled receptor (By similarity).
What are the official names of this protein?
Polycystic kidney disease protein 1-like 2, PC1-like 2 protein, Polycystin-1L2.
What is the protein family that this protein belongs to?
Belongs to the polycystin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YBGQ_ECOLI
Sequence: MNIYRLSFVSCLVMAMPCAMAVEFNLNVLDKSMRDRIDISLLKEKGVIAPGEYFVSVAVNNNKISNGQKINWQKKGDKTIPCINDSLVDKFGLKPDIRQSLPQIDRCIDFSSRPEMLFNFDQANQQLNISIPQAWLAWHSENWAPPSTWKEGVAGVLMDYNLFASSYRPQDGSSSTNLNAYGTAGINAGAWRLRSDYQLNKTDSEDNHDQSGGISRTYLFRPLPQLGSKLTLGETDFSSNIFDGFSYTGAALASDDRMLPWELRGYAPQISGIAQTNATVTISQSGRVIYQKKVPPGPFIIDDLNQSVQGTLDVKVTEEDGRVNNFQVSAASTPFLTRQGQVRYKLAAGQPRPSMSHQTENETFFSNEVSWGMLSNTSLYGGLLISDDDYHSAAMGIGQNMLWLGALSFDVTWASSHFDTQQDERGLSYRFNYSKQVDATNSTISLAAYRFSDRHFHSYANYLDHKYNDSDAQDEKQTISLSVGQPITPLNLNLYANLLHQTWWNADASTTANITAGFNVDIGDWRDISISTSFNTTHYEDKDRDNQIYLSISLPFGNGGRVGYDMQNSSHSTIHRMSWNDTLDERNSWGMSAGLQSDRPDNGAQVSGNYQHLSSAGEWDISGTYAASDYSSVSSSWSGSFTATQYGAAFHRRSSTNEPRLMVSTDGVADIPVQGNLDYTNHFGIAVVPLISSYQPSTVAVNMNDLPDGVTVAENVIKETWIEGAIGYKSLASRSGKDVNVIIRNASGQFPPLGADIRQDDSGISVGMVGEEGHAWLSGVAENQLFTVVWGEQSCIIHLPERLEDTTKRLILPCH
What is the function of this protein?
Could be involved in the export and assembly of the putative YbgD fimbrial subunit across the outer membrane.
What are the official names of this protein?
Uncharacterized outer membrane usher protein YbgQ.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: TERT_OXYTR
Sequence: MSAKKPVQSKLNIGNPTIPVTSNRSTAPKPVPGQPQFVNQEKKQQSQNTTTGAFRSNQNNANSGGNGNFELDDLHLALKSCNEIGSAKTLFCFFMELQKINDKIPSKKNTELIKNDPQFQYFCHNTILCTEQSYDEKTIEKLAKLEYKLEYKNSYIDMISKVIKELLIENKLNKLQTFGYKLVNNEFGNQNHLGMMQQNQDSSHNSNFMVKCDYINLNKQCMITKNWEKVYFYLGDHLFMHIYKEYMIFLKTRDESLVQISGTNIFCYLNEKLGRLQAAFYEGPNKNAANSAAQGSNPEANDLISAEQRKINTAIVMKKTHKYNIKAADESYLTNQEKGFWDDQIKRNRLFYCAHQNRFFQKHILNSKTLSQQQIRDNIYKEVFGFNRVRAELKGKVMSIIEQVIVNQKKFDFKYYLSKNCPLPENWKNLKKSFLEDAAVSGELRGQVFRQLFEYQQDQRQISNFLTEFVANVFPKNFLEGKNKKIFNKKMLQFVKFNRFESFTKISLLNKFRVNEVSWLSFKCKDENKKFFMNENEHVFFKVLKWVFEDLAITLMRCYFYSTEKAKEYQRIFYYRKNIWNMIMRLSIDDLLKQNLKQVEKKEMRIFCESQNFAPGKLRLIPKGDTFRPIMTFNRKIPNQVGKFQSRMTTNNKLQTAHMMLKNLKSKMFKHSFGFAVFNYDDIMKRYENFVQKWKQINSPKLYFVAMDIEKCYDNVDCERVVNFLQKSDLMDKEYFILNTFVLKRKNNIIVERSNFRKLPIKQYFRYKFQKIGIDGSSYPTLFEILEDEFNDLNMKRTIIVEQEQRKKFPKNDLLQPVLKICQNNYVTFNKKQYKQMKGIPQGLCVSYILSSFYYANLEENALQFLRKESMDPEKPEINLLMRLTDDYLLMTTEKNNAMLFIEKLYQLSLGNFFKFHMKKLKTNFALNLQKIGCTNTTQDIDSINDDLFHWIGISIDIKTLNIIQNINIKKEGILCTLNVNMQTNESILWLKKKLKSFLMNNISFYFKSTINTKQFANITLSKLYIAAAEKYVACCQEFKRFHENTSLGGQNIDIKIIHIIYVVIRSFFKYLVCNVKSPVFERDDYQQFFIYSLKFFITRFKQQKNEFAGVYKILKAKEKKLEVAKIEFQIQ
What is the function of this protein?
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes.  It elongates telomeres.  It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme (By similarity).
What are the official names of this protein?
Telomerase reverse transcriptase, Telomerase catalytic subunit, Telomerase subunit P133.
What is the protein family that this protein belongs to?
Belongs to the reverse transcriptase family. Telomerase subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: SPEE_ECOSM
Sequence: MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDALASQPS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFB7_MOUSE
Sequence: MRIHYVLFAFLLVLLSPFAAFSQDINSKRACYREGGECLQRCIGLFHKIGTCNFRFKCCKFQIPEKKTKIL
What is the function of this protein?
Has bactericidal activity.
What are the official names of this protein?
Beta-defensin 7, BD-7, mBD-7, mBD7, Defensin, beta 7.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family. LAP/TAP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3522_METJA
Sequence: MLELRSLSIRGGIAVLECGRRCISAINLKTGDKIWEFKTEWDIESISIKDNRVMLKCNGRRHIYIDLKTGRKIRELIIL
What are the official names of this protein?
Uncharacterized protein MJECL22.
Protein: E4PD_SHELP
Sequence: MIKVAINGYGRIGRSILRALYESGKRDQIQIVAINELANPEAMLHLTQYDTTHGRFQSPASLDANVMTIGDDRIQLLHEADAEKLPWRSLDIDIVFEATGALIDRQACEAHIRAGAKQVLISHPSSGDVDATIVYGVNHQDLKAEHKVVSNASCTTNCLVPIIQVLDRAFKVRSGAITTIHSAMNDQQVIDAYHDDLRRTRAAGQSIIPVDTKLARGIERILPEMKDKFEAISVRVPTINVTAIDLSVTLDKRVDIDTVNQVLSQAANGSYQGVVGYTNAPLVSCDFNHDPRSSIVDGTQTRVSDGHLVKLLLWCDNEWGFANRMLDTSLEMIKAVRA
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDPK2_PLAF7
Sequence: MGNHLSVNKLKRKKKKKSFLNIYGKNTNENTSKQSNDYKYDINTSCISREGTTTLERKNLILCHSGKLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPYYVAPQVLDGKYDKKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPWITQMTKSHEHVELSSTLLKNLKNFKKENELKKIALTIIAKHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKKK
What is the function of this protein?
Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase (PubMed:23792132).  During male gametogenesis in the mosquito gut, required for male exflagellation, possibly by regulating male gamete exit from the host erythrocytes (PubMed:29042501).  Not required for asexual blood stage proliferation (PubMed:29042501).
What are the official names of this protein?
Calcium-dependent protein kinase 2, PfCDPK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
Protein: RL6_SYNP2
Sequence: MSRIGKKPIPIPDKVTVTLNGANVAVKGPKGSLERTLPEKVTVTQEDNTIVVSPVDNSRTARERHGLCRTLVANMIEGVSQGYSKQLEIIGVGYRAQVQGNKLTLNVGYSKPVEMQMPEGVTAAMGEKNTQVIISGIDKEVVGNTAAKVRAVRPPEPYKGKGIRYQGEYIRRKAGKAGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.