PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_CUPNH
Sequence: MSDALIATSSEAPQSPAEQYDPTRKQKSADKTARIPIKIVPAEKLKKPDWIRVKAATGSSRFYEIKDILRANNLVTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDVNEPGNLARTIAQLKLNYVVITSVDRDDLRDGGAQHYVDCISQTRELSPATRIEVLVPDFRGRLDKALDILQACPPDVMNHNMETVPRLYKQARPGADYEHSLKLLQEFKRRNPNVPTKSGLMVGLGETDEEILEVMRDMRAHDIDMLTIGQYLAPSNHHLPVLRYVHPDTFKMFEEEAYKMGFTHAAVGAMVRSSYHADQQAHQAGFA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_LIGS1
Sequence: MAKKKSKKYLEAAKQVEEGKLYNASEAFGLVKKIDFANFDATIEVAFNLNVDTKQADQQLRGAMVLPNGTGKDQTVVVFAKGAKAQEAKDAGADVVGDDDLVARIQDGWLDFDVAIATPDMMAQVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVTDAKSGQVTYRTDRDGNVHVPLGKVSFTEEALEGNFKAVYDVIAKARPASVKGVYIKHVSVASTFGPSVTLDTTAL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: EPMA_YERP3
Sequence: MSDTASWQPSAPIANLLKRAAIMAEIRRFFADRGVLEVETPTMSQATVTDIHLVPFETRFVGPGAADGLTLYMMTSPEYHMKRLLAAGSGPIYQLGRSFRNEEAGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQILDCNSAETLSYQQAFLRHLNIDPLSAEKAQLREVAAKLDLSNIADTEEDRDTLLQLLFTVGVEPYIGRDKPAFIYHFPASQASLAEISTEDHRVAERFEVYFKGIELANGFRELTDGDEQLQRFEQDNRNRAKRGLPQNPIDMNLIAALKQGLPDCSGVALGVDRLVMLALNAERLSDVIAFPVNIA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: RPOC_VIBC3
Sequence: MKDLLNFLKAQHKTEEFDAIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDMPLRDIERVLYFEMYVVTEPGMTDLERGQMLTEEEYLDRLEEWGDEFTAKMGAEAIKDLLASMDLPAEAEQMREELDTTNSETKRKKLTKRLKLVEAFVASGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLETRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTREKINAKGEGMYLTGPAEAEKAYRTKTAELHARVKVRITETIKHENGKLTTETKMIDTTVGRAMLWQIVPKGLPYSLVNQKLGKKQISNLLNEAYRKLGLKDTVIFADQIMYTGFAYAALSGVSVGIDDMVVPAAKYTEIAEAEEEVREIQEQFQSGLVTAGERYNKVIDIWASTNDRVAKAMMENLSSEQVINRQGEQEKQESFNSIYMMADSGARGSAAQIRQLAGMRGLMARPDGSIIETPITANFKEGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDVVVTEHDCGTLEGVVMTPHIEGGDVKVALTELALGRVVSEDILKPGTDEVLIPRNTLLDEKWCKVINDNSVDQIKVRSVVTCDSDFGCCAQCYGRDLARGHLVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAAENSIQAKNNGSVKLHNAKFVTNKDGKLVITSRASELTIIDEFGRTKEKHKLPYGSMLSKADGDAVAAGETVANWEAHTMPIITEVAGRVQFVDMIDGVTVSRQTDDLTGLSSSEVTEAAARPAAGKDMRPAIKLVDANGKDVLIPGTDMPAQYFLPGKAIVNLDDGAEVNVGDTLARIPQKSGGNKDITGGLPRVADLFEARKPKEPAILAEHSGTVSFGKETKGKRRLIITRDSGDTYEEMIPKHRQLNVFEGERIERGDVIADGPESPHDILRLRGIHAVTTYIANEVQEVYRLQGVKINDKHIETIVRQMLRKCTITFAGDSEFLPGETVEYSQVKIANRKLVEEGKEPARFERELLGITKASLATESFISAASFQETTRVLTEAAVSGKRDDLRGLKENVIVGRLIPAGTGFAYHQDRQAKRAQEQQGPSAEQATDNLAALLNAGFSSDDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RUVB_DESAH
Sequence: MSDGILSFSSKNDKRGETSGKELITPSSQPVDDSSEVVSLRPDRFESYVGQTDTVETLKIAIQAAKMRGDCLDHVLLHGPPGLGKTTISHIIANEMGGTLTVTSGPALEKGGDLIGMLTNLARGDILFIDEIHRLPKTVEEFLYPAMEDFAVDFVFDKGLHARSHRYRLKQFVLVGATTRVGLISSPLRDRFGIFRSLDFYTDEELVTIIRRSAGLLNVVLDDGAALELARRSRGTPRIANRLLKRVRDFSMVRSSGEVTQKSVAAALSLEGIDSKGLTVLDRNYLRTIIEFYRGGPVGIEAVAATLQEETDTLVDVVEPYLLKIGMVMRTSAGRRASVGAYEHLGIKHQMELF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RS3_ALKMQ
Sequence: MGQKVNPHGLRVGVIKDWDAKWYANKRDFSDYLIEDHSIRKFVKKKLFLSGINKIETERAANNRVKINVHTAKPGMVIGKGGIGVEELRKELEKMTKKTVIVNVVEVKRPEVESQLVAENIAFSLERRVSFRRAMKQAMQRAMRAGAKGIKVSTAGRLGGADMARTEGYSEGNVPLHTLRADIDYGFAEADTTYGKLGIKVWIYKGEILPTKGKNEETNNETADNSRGRRREAK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TPIS_HAEIE
Sequence: MARRPLVMGNWKLNGSKAFTKELIEGLKAELHDVTGCDVAIAPPVMYLGTAEAALSGCGCNCGGKSVIQLGAQNVDINVKGAFTGDISTEMLKDFGAKYIIIGHSERRTYHKESDEFVAKKFGALKEAGLVPVLCIGESEAENEAGKTEEVCARQIDAVINALGVEAFNGAVIAYEPIWAIGTGKSATPAQAQAVHAFIRGHIAAKSQAVAEQVIIQYGGSVNDANAAELFTQPDIDGALVGGASLKAPAFAVIVKAAAAAKN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR2_PICAN
Sequence: MEKINVLVVGNGGREHALVWKLAQSPWAKHIFVAPGNGGFSKLENVTSVPIGSSPSDFGSLVDFATKHNVGLVIPGPEQPLVDGITTWFQKAGIPVFGPSAKAARMEGSKTFSKDFMKKHNIPTARYENFTDYEAAKQYIANSSHNLVIKASGIAAGKGVLIPANKQEAYEAIKEIMVNKQFGSAGDEVVIEEFLEGDELSILCISDGYSFVDLPPAQDHKRIGDGDTGLNTGGMGAYSPAPIGTPSLLEKIRKNILKPTIDGMRKDGYPMVGCLFVGVMVTPDGDPKVLEYNVRFGDPETQTVLPLLKSDLLELMLATVEHRLDSVDFQVHADKYSTTVVVAAGGYPESYRKGDEITVKEPLPENTFIFHAGTKEENGKVVTAGGRVIAATAIADTLEEAVKKAYVGVDHISFKDKYNRTDIAHRAFKEKPKNKVSLTYEDAGVSVDAGNQLVEKIKKSVKSTKRPGADSEIGGFGGLFDLQRAGYTDINNTLLVAATDGVGTKLRVAQIMDIHNTVGIDLVAMNVNDLVVQGAEPLMFLDYFATAHLDIKVAADFVEGVADGCKLSGCALVGGETSEMPGMYAPGHYDTNGTAVGAVLKENILPKKDKMNAGDVLLGIASDGVHSNGFSLIRKIIETTDYSYTDPAPWNPKSTIGEEVLIPTRIYVKQLLPATRRGLILGLAHITGGGLVENIPRAIPDNLSAEVDMTTWNVPEIFKWLGKTGGVPINDILKTLNMGIGMVAIVKPENVEEVIKVLKEAGETVYTIGKLVERKDLPGCTIKNSEDLY
What is the function of this protein?
Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
What are the official names of this protein?
Bifunctional purine biosynthetic protein PUR2,5, OpPUR2,5.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: DUS2_BACSU
Sequence: MTENFWRELPRPFFVLAPMEDVTDVVFRHVVSEAGRPDVFFTEFTNSESYCHPDGKDSVRGRLTFTEDEQPIVAHIWGDKPENFRKMSIGMAELGFKGLDINMGCPVPNVAGNGKGSGLICRPAVAAELIQAAKAGGLPVSVKTRLGYTDVDEWREWLTHILKQDIANLSIHLRTRAEMSKVDAHWELIPEIKKLRDEVAPDTLLTINGDIPDRQTGLKLAEQYGVDGIMIGRGIFTNPFAFEKEPKEHSSKELLDLLRLHLDLHDEYSKEEARPYKPLPRFFKIYLRGFRGASELRNQCMNTKSTDEVRALLDDFERKYLDGIE
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase 2.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: TDL1B_ORYSJ
Sequence: MADCTTMRLASSVTIILLLLVASQALVVSGESSSSAMQSKTLNMNKLLNISEDHSPNGGRHWMQRMQPDSCSEQNVVVYQNNAEHLPSGIPTYSVEIINVCTACTVYDVHISCGEFASAELVDPSQFQRIGFNDCLVKGGGRLGPSEAVSFQYSNSFAYPLAVANVACE
What is the function of this protein?
May play a role during anther development.
What are the official names of this protein?
TPD1 protein homolog 1B, TPD1-like protein 1B, OsTDL1B.
Protein: LPAT2_BRANA
Sequence: MAMAAAVIVPLGILFFISGLVVNLLQAVCYVLVRPMSKNTYRKINRVVAETLWLELVWIVDWWAGVKIQVFADDETFNRMGKEHALVVCNHRSDIDWLVGWILAQRSGCLGSALAVMKKSSKFLPVIGWSMWFSEYLFLERNWAKDESTLQSGLQRLNDFPRPFWLALFVEGTRFTEAKLKAAQEYAASSELPVPRNVLIPRTKGFVSAVSNMRSFVPAIYDMTVAIPKTSPPPTMLRLFKGQPSVVHVHIKCHSMKDLPEPEDEIAQWCRDQFVAKDALLDKHIAADTFPGQKEQNIGRPIKSLAVVVSWACLLTLGAMKFLHWSNLFSSWKGIALSAFGLGIITLCMQILIRSSQSERSTPAKVAPAKPKDNHQSGPSSQTEVEEKQK
What is the function of this protein?
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position.
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase 2, Lysophosphatidyl acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PTH_ALBFT
Sequence: MIKLFVGLGNPGPEYEFTRHNAGFWWLDAVARELKASLAMDKTYHGLVTRVTVNGQAVWLLKPQTFMNLSGKSVAALARFFKIEPQEILVAHDELDIVPGEAKLKLGGSHAGHNGLRDIHAQLGTDDYWRLRLGVGHPGVKSEVINWVLKKPSLDHRLAMDQCIARAITALPHLLAGDMDKATLLIHTSKPPRPKPPRPENTLPAVP
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSY_METAC
Sequence: MFNKFKEKLGSFKKALSKTIDEKAVEVEPVVVEQMPQSEESLEEEIEPIVEEEALEAALEAESSEAETEAASPAIAHVPIEDLKKAEYRKKLKDLKKVGEKKVEEEKPPEEKKSFFKKVVPKVGFAQKAKALVFNREVYLDNKDLEEPLWELEMGLLESDLALSVSEAIVESVKNQLTGTTKRIGSNTGEIVEAALKKAILEVVSANTFDFDEYVKNREKPVHIVFVGINGTGKTTSISKITNRLLKSGYSVVLAAGDTFRAGAIDQLGIHANRLGVKMIKHQAGADPAAVIYDAVQYAKAHKIDFVLSDTAGRMHTNMNLMAQMEKICRVSTPDLIIFVDEAVAGNDAVERAAQFNEAVPIDGSILTKIDADAKGGAAISIAYITGKPILFFGIGQGYEDLKKFDPEWFVDQLFNQ
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: THIE_METAC
Sequence: MNQKNSNPKNPPRKISLLKQIDFYLVTDSGLSKKGTLSDVREAVDAGCKIVQYREKNKSTKEMIDEASEIKRICGDRAIFLVNDRIDVALAVDADGVHIGQDDMPIEIAKKLLGPEKIIGLTVHNVEEALEAERNGADYVGLGSIFDTSTKKDAGKGIGPASIKEVKNAIKIPVVAIGGINRENCIPVVENGADSFVAISAVVCSDDVKRETRKFIEIIREIKNSGRQ
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: BRKP1_PHAJA
Sequence: RPPGFSPFRIY
What is the function of this protein?
May produce in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle (By similarity).  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
Phyllokinin.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2274_MYCBO
Sequence: MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIAAVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator Mb2274c.
Protein: GPDA_MESFL
Sequence: MSKKNITIIGTGAYGTALANVLADNDNNVIMYGIVEQQVDDINIYHQNSVFFDNKKINKTIRATNSMAAALENTDILILGVPTAAIKHVVNDIIKYAKKPMDIINTAKGLDEENLGLLSDKIKKYFEGSNVISTYSALYGPSIAIEVVDRQPTAIMIASETIEKAKELCNVFSNEYFYMYPTTDIAGCEISAALKNAIAIGGGILKAYNAGDNAHATLLTLGLNEMYEFGKHFGAKLETFLNFAGLGDLILTASSKKSRNFRLGERIVELNDAKKALESFNLTVEGVETARIAHEIGVKYQISMNFFEIIYNILYNNVKPISLLNNVFRDVKLV
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF6_HUMAN
Sequence: MNQSRSRSDGGSEETLPQDHNHHENERRWQQERLHREEAYYQFINELNDEDYRLMRDHNLLGTPGEITSEELQQRLDGVKEQLASQPDLRDGTNYRDSEVPRESSHEDSLLEWLNTFRRTGNATRSGQNGNQTWRAVSRTNPNNGEFRFSLEIHVNHENRGFEIHGEDYTDIPLSDSNRDHTANRQQRSTSPVARRTRSQTSVNFNGSSSNIPRTRLASRGQNPAEGSFSTLGRLRNGIGGAAGIPRANASRTNFSSHTNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEPIRLRSTSNSRSRSPIQRQSGTVYHNSQRESRPVQQTTRRSVRRRGRTRVFLEQDRERERRGTAYTPFSNSRLVSRITVEEGEESSRSSTAVRRHPTITLDLQVRRIRPGENRDRDSIANRTRSRVGLAENTVTIESNSGGFRRTISRLERSGIRTYVSTITVPLRRISENELVEPSSVALRSILRQIMTGFGELSSLMEADSESELQRNGQHLPDMHSELSNLGTDNNRSQHREGSSQDRQAQGDSTEMHGENETTQPHTRNSDSRGGRQLRNPNNLVETGTLPILRLAHFFLLNESDDDDRIRGLTKEQIDNLSTRHYEHNSIDSELGKICSVCISDYVTGNKLRQLPCMHEFHIHCIDRWLSENCTCPICRQPVLGSNIANNG
What is the function of this protein?
E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation.  Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover.  Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity.  May also bind DNA and function as a transcriptional regulator.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF6, RING-type E3 ubiquitin transferase RNF6.
What is the protein family that this protein belongs to?
Belongs to the RNF12 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, axon. Nucleus, PML body. Note=Localizes to the PML nuclear bodies in Sertoli cells.
Protein: TRMB_BURMA
Sequence: MIHDDDPNAPGAPHDDATAAPASATRAAPAAGDDDDANPLHLRRIRSFVTRAGRVSTGQRRAIDELGPRFVIPYGSAQPDWDAIFGRRAPRVLEIGFGMGASTAEIAALRPGDDFIGVEVHEPGVGALLKLIGEQQLSNIRIIQHDAVEVLAQMIAPDSLDGVHIFFPDPWHKARHHKRRLIQPPFVAQLAAHLKPGAYLHCATDWQNYAEQMLEVLSADPSLENTAQNYAPRPGYRPVTKFERRGLRLGHGVWDLVFRKKHAG
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: MPK4_ARATH
Sequence: MSAESCFGSSGDQSSSKGVATHGGSYVQYNVYGNLFEVSRKYVPPLRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIRSNQPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRITVDEALCHPYLAPLHDINEEPVCVRPFNFDFEQPTLTEENIKELIYRETVKFNPQDSV
What is the function of this protein?
The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis.  Essential to promote the progression of cytokinesis and for cellularization (formation of the cell plate) during male-specific meiosis.  Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule-associated proteins such as MAP65-1.  Involved in root hair development process.  Negative regulator of systemic acquired resistance (SAR) and salicylic acid- (SA) mediated defense response.  Required for jasmonic acid- (JA) mediated defense gene expression.  May regulate activity of transcription factor controlling pathogenesis-related (PR) gene expression.  Seems to act independently of the SAR regulatory protein NPR1 (Nonexpresser of PR1).  Phosphorylates MKS1 and transcription factors WRKY25 and WRKY33.  The MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity (PubMed:11163186, PubMed:15225555, PubMed:15358537, PubMed:15990873, PubMed:18982020, PubMed:20215588, PubMed:20802223, PubMed:21098735, PubMed:21575092, PubMed:25770109).  Phosphorylates MEKK2 upon treatment with flg22 (PubMed:22643122).  Involved in stomatal movement regulation by repressing HT1 and HT1-mediated GHR1 phosphorylation (PubMed:27694184, PubMed:27923039).
What are the official names of this protein?
Mitogen-activated protein kinase 4, AtMPK4, MAP kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Note=Translocated into the nucleus in response to phosphorylation (Probable). Localized to the cell plate.
Protein: TPS1_SORBI
Sequence: MAALQYNCDAGLAKAPTFHPSLWGDFFLTYQPPTAPQHVYMKERAELLKEEVREIVKGTNELPKLLDLIITLQRLGLDNHYEIEIDEHLHFIYNSSCDVKDLNLVSLRFYLLRKNGYDVSSDVFLNFKDKDGNFASDDIRSLLSLYNAAYLRTHGEEVLDEAIIFTRRHLEAALTSLESKLADEVSLSLQTPLFRRVRILETRNYIPIYEMEPSRNEAMLEFAKLNFNLLQILYCEELKTVTAWWKQLNIETDLSFIRDRIVEMHFWMAGACSEPKYSLSRVILTKMTAFITILDDIIDTHSTTEEGKLLAKAIDRCSQDANEVLPDYMKHFYMFLLKTFDSCEDELGPNKRYRVFYLKELLKILVRGYSQEIEWRDEHYVPETIDKHLEISRVTVGAFQLACSSFVGMGDIITKEVLDWLLTYPELLKCFTTFVRLSNDITSTKREQTGGHHASTVQCYMMEHSTTMHDACEKIKGLIEDSWKDMMQLYLTPTEQSKVVAQTVVDFARTGDYMYKKTDAFTFSHTIKDMIALLYVEPILF
What is the function of this protein?
Sesquiterpene synthase converting farnesyl diphosphate into two major products, zingiberene > beta-sesquiphellandrene, and five minor products, 7-epi-sesquithujene, sesquisabinene A, (E)-alpha-bergamotene, (E)-beta-farnesene and beta-bisabolene.  Can also accept geranyl diphosphate as substrate, producing nine monoterpenes, with myrcene, limonene and alpha-terpinolene as the major products.
What are the official names of this protein?
Zingiberene synthase, SbTPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_VITVI
Sequence: MIFSTLEHILTHISFSVVSIVITIHLITLLVDEIVGLSDSSEKGMIATFFCITGLLVTRWIYLGHFPLSDLYESLIFLSWSFSIIHIVPYFKKHKNHLSALTAPSAIFTQGFATSGLLTEMHQSEILVPALQSQWLMMHVSMMVLGYAALLCGSLLSVALLVITFRQDIRILCKNNHFLNKSFSFDEIQYMNKGNNVLQNTSFLSVRNYYRAQFIQQLDHWSYRVISLGFLFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHTRTNKNLQVANSAIVASMGFLIIWICYFGVNLLGIGLHSYGSFTFSSNL
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: EX7L_SYNC1
Sequence: MNISEGTVSVSRLVYLLKEVVEDNFVQVLVTGEIANFSAPSSGHYYFAVKDDQAQLRGVMFRSSNRLLKFTPENGMQVLCGGRVSLYPQRGELQLVVDRMEPLGVGSWQLAFEKLKTKLDAEGLFEVGRKRRLPSFPRTIGVVTSPTGAAIHDILNVLRRRGAGLHVLLSPVRVQGDGAADEIARAIADFNRHGQADVLIVGRGGGSPEDLWAFNEEVVARAVFASRIPVISAVGHEVDVTISDLVADLRAPTPSAAAELVVQGRQELERHVDHLVMRLSGQMQGRLSLLKERLDGLRRRLRSPVDDLRRQYRDLEQLRKRLFSAMEKTMQRAANRLGLAGSRLHALSPLATLDRGYAIVFSAKTSTIVRDARTLTPGDRVQIRFAKGSVEATVDEVDHGD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL107_MIMIV
Sequence: MDKKKLFQYTLDGKFTDLELTLVDSNDTLTMHLHKVILSSSCPYFETMFSNSFSDSVSDKFRMEVINVYVMADIINSFYITDIERSQNLSEVDYQLLYTQSRNFLGLEHKIQNLEKIIFPENKFDKLLDTIDSCIGYNKETISILFYNMPMDYDLSKLPIKLLKKMSKISRYFILCIDSDRIELHNNHSCFSIGPVKLNYNCKLYKLLYSPIYHKYLMVNDTIHLIDTETDLSRISFDNNRYYCTNAVLSTDNRYVYSVYTNSTIRKFQTETTELIGVWYRDGMPIDTVNKNQGPITAFDDRPKKIMYSTPYDYIIVQYGTSLVCYKCLDMSIHWEMDNVHLPTLSQCEKYIVCLKGITGNQLCVIDIEKDSLKFGPILANCRYICNHDNTTVIIIHDYKISGSKIRVYDWVNNIFTYENESFNVSDITYIDHIENDNYIIVSHDIIDDSYISINKWNFKEDTTKLVTACYDNYSHKFYTITNFKAALQKRIKEYIDTNSN
What are the official names of this protein?
Putative BTB/POZ domain-containing protein L107.
What is the protein family that this protein belongs to?
Belongs to the mimivirus BTB/WD family.
Protein: CDS2_ARATH
Sequence: MQKEIAGDAPSAPTTRVRHRKRNSDVGAGAGKPNGNHLLVNDSKKYKSFLIRAYSTFWMIGGFALIVYLGHLYITAMVVVIQIFMARELFNLLRKTHEDKQLPGFRLLNWHFFFTAMLFVYGRILSQRLVNTVTPDKVLYRLVTSLIKYHMAICYSLYISGFVWFILTLKKKMYKYQFSQYAWTHMILIVVFTQSSFTVANIFEGIFWFLLPASLIVINDIFAYICGFFFGRTPLIKLSPKKTWEGFIGASITTVISAFLLANIMGRFLWLTCPREDLSTGWLLCDPGPLFKQETHALPGWISDWLPWKEISILPVQWHALCLGLFASIIAPFGGFFASGFKRAFKIKDFGDSIPGHGGITDRMDCQMVMAVFAYIYHQSFVVPEVLSVDKLLDQIITSLTLEEQQALLVKLGQMLQEKVIGS
What is the function of this protein?
May be involved in the synthesis of minor phospholipids and in modulation of IP3-mediated signal transduction.
What are the official names of this protein?
Phosphatidate cytidylyltransferase 2, CDP-DAG synthase 2, CDP-DG synthase 2, CDP-diacylglycerol synthase 2, CDS2, CDP-diglyceride pyrophosphorylase 2, CDP-diglyceride synthase 2, CTP:phosphatidate cytidylyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.