PharMolix/UniProtQA huggingface dataset:
Protein: ATG2A_XENTR
Sequence: MSRWLFPWSSSIKTRACRYLLQHYLGHYLEERLSLEQLSLDLYNGSGRLTDIHLDIWSVNELLDSAGAPLEIIDGFIGSISVTIPWSALVTENCTLEVSKLQVTCRPKYRGAAQGTESQSWSSCMTTSMQLAQECLKEQPEEPSEPPQPIEGLEMFAQTIETVLRRIKVTFIDTIVRIENNPGDSNLGTALEIHIKRLDYCDEAVRDSPHTVPVDIHQPPAFIQKILQLSGVSLHYEEFKTSVQTPSPTPENPLESEPVQPSKTPSWPEEPQPAPSPIQQIGSCSGCTELTIKLKQNDLFPGPKLDIDGKIGSVHLFLTPRQISNLQEILDALSISESSAIREKLLKSRPLDLEDLKLIEQDLNQQLQSGPGSLFVPDPELVPFQTIENGDMFYSMAAMTNSMTSIRSANELSDIDLESSMYSDYSSQQIPSLTPGIMLSSPRKYGRTPFSATLPQNLHKLPGKSSHPPSMELLKPEMLLRLTLGGLTVTVPHISTYISPQEDPACPEVARHFFRELGYFKDSAFSGRDFSHLRGQFEKACHLSNIRVTAVAVQLVCEQRVGGGTHQSSVDLSCGRLEILECLRQGESTSRRTKNTEYTKLMTFCSPSTSSRPCAQIHYKRSQKTPTRSSRKKQEIKVSSEILVELEEFQTDIDLGLLDRLGSIFQNGACRESYSQNDLHMTDVPQSSEDMEIRVVASKSHICLQFPVPDLRPSLERRPWAEKAVRKDCLQMEVADLDIHSQSKTGTDEARKIEITFSDLHGVYTDGEKLNVPCIRVSKGADPLAKAGGKKFIFPSILVAILPQSKVSPWYLAQDKIDDIDHPSVESPCELKQPEPSPFSSKRTMFETEEMVIPADPNEMADFQHVTLASSQYTLEITLPRAHVFFPSKEVYESLYNRLCNDLLMWEPVPELGASISDSLLSAEPHTTSNYQQDTFRMCKSAFKLDSDSDDEDSHFYSVDEAARHRRGAQDGQSYFSASVTILKGRITAWTEAKGEGAKKLDDHHGEVVLDVENGCIFSVSKYRGKEDLSYLCIQSESVALYHKATVKDYLAPVSLEIPTFLHPTNLDPTIYLSEEGVSAQLSGARKDRNQKMLSLAVRIDLNLVKNVKEFLVALRLDGATLRHHMALPYQSWHSQILDFLDVVDEPILGYSPPAVITVLHTHLFSCAVDYRPLYLPIRVLITAETFTLSSNIVVDTSTFLLRFILDDSALYLSDKCDAEVTDLRKDYVCVLDVDLLELVITTWKGNASSKLTQPLFELRCSNNVLHIHTCADSCAMLVNLTQYVMNNGDLHCPPKPEPPTEIAGQKLQPPEGPSSLPPCLPAETAQINQGDLTDALIDTGRTGKEQPETAISVDAALLEESPVSVYLFPEEIKSGNKRQTTSPSPPPLTEGRVSQESLGLSDTSGDSELTDTDDFCILDAPGIGVPPKDGEPVVRKLVDSPIAVRDGHFSRPLGSTDLLKPPAKFPVPETRIVLREISVVWHLYGGKDFGSSRPNSARAQSPRSRTSFHNARGSPSRSSVTNRPQNTWRTQGGNGRIHDILMEIQLTKVSFQHESYPEPLADGEEKLHTGDLDELPLARQVFIVQELEIRDRLASSHINKFLYLYTSEKMPRRAHSNMLTIKALHVRPEAGLGGPECYLRMSLMPLRLNIDQDALFFLKDFFTSLASGIQTIVPMELGSEASRLDGPAKSSSDCELEQETSQGSTEDETMSPSSSTDQPIYFREFRFTSEVPIWLDYQGKHVTTEQVGTFAGILIGLAQLNCSELKLKRLYCRHGLLGADKVVSYALNEWLTDIRKNQLPGILGGVGPMHSVVQLFHGVRDLFWLPIEQYRKDGRIIRGLQRGAASFGTSTASAALELSNRLVQAIQATAETVYDILSPTPPVSRCALDVRQSRKLRRGQQPADLREGVAKAYDTVREGVIDTAHTICEVASRGHEQKGLTGAVGGVLRQIPPTVVKPFIVATEATSNLLGGMRNQIRPDAHKEDALKWRADEGQD
What is the function of this protein?
Lipid transfer protein involved in autophagosome assembly.  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  Binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, and extracts phospholipids from the membrane source and transfers them to atg9 (atg9a or atg9b) to the IM for membrane expansion.  Also regulates lipid droplets morphology and distribution within the cell.
What are the official names of this protein?
Autophagy-related protein 2 homolog A.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Lipid droplet. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Localizes to endoplasmic reticulum-autophagosome contact sites.
Protein: TRMB_STUS1
Sequence: MTEQNPAAEEQQSAPRRTIKSFVMRAGRMTEGQQRGLEQGWPKYGLELADGLRDFDEVFGRSAPRTFEIGFGMGHSTLEMAAAAPEQDFIGVEVHKPGVGALLSGLVSQKLTNVRVYSCDALEVLRDCVADASLDRVLLFFPDPWHKSRHHKRRIVQPAFAELVRRKLKVGGVLHMATDWEPYAEHMLEVMNVAPGYRNLAQDGRCVPRPTERPVTKFERRGERLGHGVWDLKFQRID
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: POTA_STAEQ
Sequence: MNPLLSFKDVSKGFEDVQILNEINIDIEPGYFYTLLGPSGCGKTTILKLIAGFEYPDSGDIIYKDKPIGKMPPNKRKVNTVFQDYALFPHLNVFDNIAYGLKLKKLSKSEIKRKVTEALQLVKLSGYEHRQIQGMSGGQKQRVAIARAIVNEPEILLLDESLSALDLKLRTEMQYLLRELQSRLGITFIFVTHDQEEALALSDYIFVMKDGKIQQFGTPIDIYDEPVNRFVADFIGESNIVHGTMVEDFVVNIYGQNFDCVDMGIKENKKVEVVIRPEDISLVSQNDGLFKAKVDSMLFRGVHYEICCKDRKGYEWVIQSTKKANVGSEVGLYFEPEAIHIMVPGETEEEFDKRIESYEDYHHA
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GVPO1_HALSA
Sequence: MADPANDRSEREEGGEDDETPPASDGNPSPSANSFTLSNAQTRAREAAQDLLEHQFEGMIKAESNDEGWRTVVEVVERNAVPDTQDIIGRYEITLDGTGDVTGYELLERYRRGDMKEEL
What are the official names of this protein?
Protein GvpO 1.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: M2_I83A8
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRLFKHGLKRGPSTEGVPESMREEYRKEQQNAVDADDSHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: IFNT_GIRCA
Sequence: MAFMLSLLMALVLVSYGLGGSLGCYLSENHMLHAQKNLKLLARMNRLSPHSCLQDRKDFGLPRKMVEGSQLQKDQAISVLHEMLQQCFNLFHTERSSAAWDNTLLEQLCTGLHQQLDDLDARLGPLMGQKDSGMGRMGPILTVKKYFQGIHVYLKEKKYSDCAWEVIRVEMMRALSSSTTLQERLKKMGGNLNSP
What is the function of this protein?
Paracrine hormone primarily responsible for maternal recognition of pregnancy.  Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium.  This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity.  This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus.  In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties.  In contrast with other IFNs, IFN-tau is not virally inducible (By similarity).
What are the official names of this protein?
Interferon tau, IFN-tau, Antiluteolysin, Trophoblast antiluteolytic protein, Trophoblast protein 1, TP-1, Trophoblastin.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the uterine lumen.
Protein: CYB_HYDPE
Sequence: MAPNPRKSHPLLKMVNNSLIDLPTPSNISAWWNFGSLLALCLMTQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNMHANGASFFFICIYMHIGRGFYYGSYLHKETWNTGILLLLTLMATAFVGYVLPWGQMSFWGATVITNMFSAIPYIGQTIVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLTLIHLTFLHESGSNNPLGIVSNCDKIPFHPYYSLKDILGLTLLLLPLTTMALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLSPLLHKSKQRTMAFRPLSQLLFWTLVANLLILTWIGSQPVEHPFIIIGQLASTTYFIILLILFPITSALENKMLNF
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RT02_PROWI
Sequence: MNSTKIKEIEFQNVIVDPKINNLHLKTNTDISSNYYKAGTHIGHKSIHLSETHSWHPSMAQYHLGIRDNITICNVQQTQKCLSRAFYVLTQILDNGGNVLIVNTNPEFYKLSINSMKFIEKNLPFQTFSAISYCFYKWIGGTLTNYKQISKSIYCYVKFTQRCGKFCEKNNIDFTRYQKIKKCFQGYGSVSGDSIVMSLQKKPDVIFIFNPGDNKNLILEANRLQIPVIGCTDMSSNTNGISYPIPCNNTSVEFTLYLYKKLYKVLHYISTKKK
What are the official names of this protein?
Ribosomal protein S2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UNG_PSEU2
Sequence: MTSDDRIKLEPSWKNALRDEFEQPYMAQLREFLRQEHAAGKEIYPPGPLIFNALNSTPLDNVKVVILGQDPYHGPNQAHGLCFSVQPGVPTPPSLVNIYKELKRDLNIDIPNHGCLQSWADQGVLLLNTTLTVERANAASHAGKGWQHFTDRIIQVVSEHQPHLVFLLWGAHAQSKQKLVDATKHLVLTSVHPSPLSAYKGFLGNGHFGRANKYLEQNGIAPIDWRLPAL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_STRP3
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DAT2D_SOYBN
Sequence: MAAEPVSDGGAAAEKLISGREEFGDSSNLFSAILAMVLWLGAIHFNIALILLAVFFLPLSKSLLVFGFLFGFMVLPINEKSRFGRRLSRFICKHACNYFPITLHVEDMKAFDPNRAYVFGYEPHSVLPIGIVALADHTGFMPLPKVKVLASSTVFYTPFLRHLWTWLGLTPATKKNFISLLASGHSCILIPGGVQEAFHMQHGTEIAFLKARRGFVRVAMVKGKPLVPVFCFGQSNVYKWWKPGGKLFLKFARAIKFTPICFWGIFGSPLPFRHPMHVVVGRPIEVDKNREPTTEEVAKIHGLFVEALQDLFERHKARAGYPNLELRIV
What is the function of this protein?
Involved in triacylglycerol (TAG) synthesis.  Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA.  Can use oleoyl-CoA and linoleoyl-CoA as substrates.  May play a role in TAG biosynthesis in different tissues in responses to environmental and hormonal cues.
What are the official names of this protein?
Diacylglycerol O-acyltransferase 2D, GmDGAT2D.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet.
Protein: RPOC2_AETCO
Sequence: MAERANLVFHNKVIDGTAIKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSLILEKHHHYGNVHAVEKLRQSIEIWYATSEYLRQEMNPNFRMTDPFNPVHMMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTIRGISVSPRNKNRMMSERIFIQTLIGRVLADDIYIGSRCVAFRNQDLGIGLVNRFITFGTQSISIRTPFTCRSTSWICRFCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPYNGKIKFNEDLVHPTRTRHGHPAFLCYIDLSVIIESEDIIHSVTIPPKSFLLVQNDQYVESEQVIAEIREGTYTFRFKERVRKYIYSDSEGEMHWSTDVYHAPEFTYSNVHLVPKTSHLWILSGGSCGASLILFSIHKDQDQMNIPFLSVKRKSICSLSVNNDQVSQKFFSSDFSDKKKSGIPDYSELNGIVGTSHYNLIYSAIFHENSDLLAKRRRNRFLIPFESIQEQEQEKEFMPHSGISIAIPINGIFRKNTIFSFFDDPRYRRKSSGILKYGTIEADSIIQKEDMIEYRGVHKFKKNYKMKVDRFFFIPEEVHILPESSVIMVQNYSIIRVDTRITLNIRSQVGGLIRVERKKKRIELKIFSGDIHFPDKTDKISRHSGILIPPGRGKPNSRESKKVKNWIYVQRITPTKKKFFVLVRPVATYEIADSINLATLFPQDLFREKNNIQLRVVNYILYGNGKPTRGISDTSIQLVRTCLVLNWDQDNKNSSLEEARAFFVAVSTKGLIRDFIRIGLVKSHISYIRKRNNPPDSGLISADHMNPFYSISPKAGIQQSLSQNNGTIRMFLNRNKESQFLLILSSSNCFRMGPFDHVKYHNVINQSIKKNPLITIKNASGPLGTTIQISNFYSFFPLLTYNKMSVIKYLQLDNLKQILKVINSYLIDENGRICNRDPYSNVVLNPFKLNWYFLHQNYHHNYCEEMSTLISLGQFFCENVCIAKKGPHLKSGQALIVQMDSVVIRSAKPYLATPGAKVHGHYGEILYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISMNLEKRIKGWNKYITGILGIPWGFLVGAELTIVQSRLSLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEEGMSNVFLPGELIGLLRAERTGRALEEAISYRAILLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGGIPAGTGFNKGLVHCSRQHTNILLEKKTKNFCLFEEDMRDILFYHREFFDSSISKFERSFLGFNDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YADK_ECOLI
Sequence: MHPTQRKLMKRIILFLSLLFCIACPAIAGQDIDLVANVKNSTCKSGISNQGNIDLGVVGVGYFSGNVTPESYQPGGKEFTITVSDCALQGTGDVLNQLHIDFRALSGVMAAGSRQIFANEISSGASNVGVVIFSTQDSANTFNVLNASGGSRSVYPVMSDDMNGSSWKFSTRMQKIDPALSVTSGQLMSHVLVDIYYE
What is the function of this protein?
Part of the yadCKLM-htrE-yadVN fimbrial operon.  Could contribute to adhesion to various surfaces in specific environmental niches.
What are the official names of this protein?
Uncharacterized fimbrial-like protein YadK.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: PPI1_STAAS
Sequence: MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Putative peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: DEOB_STRSY
Sequence: MPKFKRVHLVVMDSVGIGAAPDSDKFFNAGVADTESDTLGHISEKAGLEVPNMTKIGLGNIPRDTALATVPAESHPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWDGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFSRTANRHDYAVSPFEATVLNKLADAGVPTYSVGKISDIFNGSGITNDMGHTKSNMHGVDVLIDTLKLSDFEEGFSFTNLVDFDAVYGHRRNIEGYRDCLQEFDARIPEIIDNMREDDLLLITADHGNDPSYAGTDHTREYVPLLAYSKAFKGSGVLPVGHFADISATVAENFGVDTAMIGESFLSQLV
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VWC2L_HUMAN
Sequence: MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQISSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQGKQTV
What is the function of this protein?
May play a role in neurogenesis.  May play a role in bone differentiation and matrix mineralization.
What are the official names of this protein?
von Willebrand factor C domain-containing protein 2-like, VWC2-like protein, Brorin-like.
What are the subcellular locations of this protein?
Secreted. Synapse.
Protein: PYRC_SHELP
Sequence: MTKLTITRPDDWHVHLRDGDVLTDTVRDTGRYMGRAIIMPNLVPPATNVDSALAYYERIKAVCTTNFEPLMVLYLTDNTTAEDIRAAKASGKVVAAKLYPAGATTNSDSGVTDVKNIYPVLEAMQEVGMLFLVHGEVTDSSIDIFDREATFINNTLKQVVADFPSLKIVLEHITTKDAVDFVMGASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAAASGSKKFFLGTDSAPHAKDRKEAACGCAGSYTAHAAIELYAEAFESVGALDKLEAFASFNGPDFYGLPRNTDSITLVKRSWEVPATYPLGDTGVVPIRAGETIDWQVED
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: TNNC1_MOUSE
Sequence: MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKMMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE
What is the function of this protein?
Troponin is the central regulatory protein of striated muscle contraction.  Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C.  The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
What are the official names of this protein?
Troponin C, slow skeletal and cardiac muscles, TN-C.
What is the protein family that this protein belongs to?
Belongs to the troponin C family.
Protein: PSME_DICDI
Sequence: MSKNNSTVIKMDEQVLKYKEDLYEKTVHHLKVTIPKKIAEYQELAKSYGQNSENEQDGQTSKKRKLDSEDYVLMPIEDLIKTNRVIMETHQKFKKAYIELIETFSVIRGWISLNIPRIEDGNNFGVDVQEDIITQITKLEEVYTSLLDGSESYFASRASLVKKILKHKDIEAYRYSLAQVDEKEFTRFSFSYFDLANNYATTYSLIVKNFAKLETPRPTNASNIY
What is the function of this protein?
Subunit of the 11S REG (also called PA28) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome.  11S REG-gamma activates preferentially the trypsin-like catalytic subunit of the proteasome.  May also be involved in cell cycle regulation.
What are the official names of this protein?
Proteasome activator 28, PA28 homolog.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: POLG_WMV2A
Sequence: KYLEVLDFNHIDGCCESVSLQSGKEAVENLDTGKDSKKDTSGKGDKPQNSQTGQGSKEQTKIGTVSKDVNVGSKGKEVPRLQKITKKMNLPTVGGKIILSLDHLLEYKPNQVDLFNTRATKTEFESWYSAVKIEYDLNDEQMGVIMNGFMVWCIDNGTSPDVNGVWVMMDGEEQVEYPLKPIVENAKPTLRQIMHHFSDAAEAYIEMRNSESPYMPRYGLLRNLRDRELARYAFDFYEVTSKTPNRAREAIAQMKAAALAGINSRLFGLDGNISTNSENTERHTARDVNQNMHTLLGMGPPQ
What is the function of this protein?
Involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.
What are the official names of this protein?
Genome polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae genome polyprotein family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion.
Protein: HVM33_MOUSE
Sequence: EVKLEESGGGLVQPGGSMKLSCVASGFTFSNYWMNWVRQSPEKGLEWVAEIRLKSHNYATHYAESVKGRFTISRDDSKSSVYLRMNNLRPEDTGIYYCTTGFAYWGQGTLVTVSA
What are the official names of this protein?
Ig heavy chain V-III region W3082.
Protein: GCSPA_LEGPH
Sequence: MPYIPHTPDDTKEMLEAIGAQDIQDLFDEIPASLQYAGFQNIPAGINEMEMLKEAQNQAQKNRNGICFIGAGCYEHHIPAAVWDIASRGEFLTAYTPYQAEASQGTLQLLYEYQTMICELTGMEVSNASMYDGATALAEAVLMAVRLNKHSKTNRVLIAGTVHPFYRETIETIVRNQHIEVITLPFDEQQGITNLGSLNQYTGEDITALVIAQPNFFGCLEQVDKMTSWAHHNKTISVACVNPTSLALLKPPGSWGEHGVDIVCGEGQPLGSPMASGGPYFGFLSTRMAHVRQMPGRIIGRTVDKDGKTGFSLTLQAREQHIRRAKATSNICTNQGLLVTAATIYMSLLGPEGLSQVATQCHQNTHELITALTQIEGVELAFKAPFFHEALIKLNQPVQSVLQQLADAGIAGGYAPEQHYPQLANTLLVCATEVRTAEDIAKYAKTLKTIMSKRGA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: HSP1_COTJA
Sequence: MARYRRTRTRSRSRRRRRSRRRRSSRRRRYGRSRRSYRSVGRRRRRYGRRRRRRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm histone, Protamine.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YL079_MIMIV
Sequence: MKEAVKNVKPKVPAKKRIITGSKTKKKVFVKKKPPDKKPLKKPVKKTVKTDKPKSIYVPNKDLKISKWIPTPKKEFTEIETNSWYEHRKFENPNKSPVQTYNKIVPVVPPESIKQQNLANKRKKTNRPIVFISSEKIRIYPTKDQQKILQTWFRLFAYMYNCTIDYINSKKVVLESGRINVAATRKVCNKISVRKAQKTIRDNLIQSTNPSIMTHIIDEAIGLACSNYKTCLTNYIERHIKKFDIKPWNMSKRKKIIIIEANFFKKGTFCPTVFPKMESSKPLTMIDKTVTLQYDSDTRKYILFVPRVTPKYSVNKEKNSCGIDPGLRDFLTVYSENETQSICPIEIVVNTTKNEYKKIDKINEIIKTKPNLNSKRKKKLNRGLRKYHRRVTNKMKDMHYKVSHELVNTFDKICIGKLNVKSILSKANTVLKSALKRKLATLSFYRFTQRLTHMGYKYGTEVVNVNEYLTTKTCSNCGKIKDLGASKIYECESCGMYADRDENAAKNILKVGLKPWYKQK
What are the official names of this protein?
TnpB-like protein L79.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transposase 35 family.
Protein: PSBL_PLAOC
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.