PharMolix/UniProtQA huggingface dataset:
Protein: GBB2_TOBAC
Sequence: MSVKELKERHMAATQTVNDLREKLKQKRLQLLDTDVSGYARSQGKTPVIFGPTDLVCCRILQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPSGQSVACGGLDSVCSIFNLNSPIDKDGNHPVSRMLSGHKGYVSSCQYVPDEDTHVITSSGDQTCVLWDITTGLRTSVFGGEFQSGHTADVQSVSISSSNPRLFVSGSCDSTARLWDTRVASRAQRTFYGHEGDVNTVKFFPDGNRFGTGSDDGTCRLFDIRTGHQLQVYYQPHGDGDIPHVTSMAFSISGRLLFVGYSNGDCYVWDTLLAKVVLNLGAVQNSHEGRISCLGLSADGSALCTGSWDTNLKIWAFGGHRSVI
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family.
Protein: DNAJ_STAAB
Sequence: MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNASQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_HAEIN
Sequence: MNSKLSLSTKLSSSGKTQLAEYFATPPFKVITLPSYDDAWANGLNAMQMSSSPGVLAGDLLEIDISLAKLTALSLNTQAFTRVQAMNEGDSAMQTTHILLAENSRLFYLPHPLVLHRDSVFKQQTQIEMGEQSELIYGEIVAIGRVLNDERFAFRQFSSHLKIYALQNDGKKRPLVSDCIQWLPSKMNLTALSQMENYSHQGSLTYLNLAKNNAEIKQQVQALQQQSTEEKDLLIGISQLNEYGLMVRVLGCRAEANSEII
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_ECOSM
Sequence: MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RL18_STRAW
Sequence: MAYGVKIAKGDAYKRAAIKRRHIRIRKHISGTAERPRLVVTRSNRHIVAQVIDDVKGHTLASASTLDTTIRGGESDKSAQAKSVGALVAERAKAAGVEAVVFDRGGNQYAGRIAALADAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GLB_NERAL
Sequence: GDVDVLKSLSADQKAAIKSSWAAFAADITGNGSNVLVQFFKDYPGDQSYFKKFDGKKPDELKGDAQLATHASQVFGSLNNMIDSMDDPDKMVGLLCKNASDHIPRGVRQQQYKELFSTLMNYMQSLPGANVAGDTKAAWDKALNAMANIIDAEQKRL
What are the official names of this protein?
Globin, Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL5_ACTSZ
Sequence: MAKLHDYYRDQVVNELKTKFNYASVMQVPRIEKITLNMGVGEALTDKKLLDNAVADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKNDEEGQALLAAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RUVB_ALBFT
Sequence: MSIQTDDFAAPPPKRILSGAPASPNEEAVERALRPKLLDEYVGQAKVREQLEIFISAARMRDEALDHVLLFGPPGLGKTTLSHIIAHELGVNLRQTSGPVLEKPKDLAALLTNLEKNDVLFIDEIHRLSPVVEEILYPALEDYKIDIMIGEGPAARSIKLDLQPFTLIGATTRAGMLTNPLRDRFGIVARLEFYSPEELASIVRRSAGLLKVPTDEKGGFEIARRSRGTPRIANRLLRRVRDYADVKGAGEITLDIAHRALVMLDVDPQGFDLMDRKLLEAVIHRFDGGPVGLDNIAASIGEERETIEDVIEPYLIQQGYLQRTPRGRIATLAAYKHLGVTPPAAQSGGDMFGAMRPE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MATK_NYMAL
Sequence: MEKLQYELQGYLEIDRYRKQRFLYPLLFREYIYALAHDHGLNSSIFYEPTENLGYDNDNKSSSLIVKRLITRLHQQNHLTISVNDSRFVGPNRSFYSQTIPEGFAGIMEIPFSVRLVSSLERERIAKYHNLRSIHSIFPFLEDKLSHLYYVSDILIPYPIHLEILLQTLRTRIRDAPSLHLLRCFLHEHHNWNSLITSNKSISIFSKENQRLFLFLYNSHVYECESVLVFLRKQSSHLRSISSLAFLERTHFYGKIKHLVVTPRNDSQRTLPLWFFKEPLMHYVRYQGKSIMASRCTNLLMKKWKYYLVNFWQCHFHLWSQPGRIHINELSNHSFYFLGYLSGVRLTPWVIRSQMLENSFMIDTAIKRFDTIVPIFPLIGSLVKAKFCNVSGYPISKSVWADSSDSDIIARFGWICRNLSHYHSGSSKKHSLCRIKYILRLSCARTLARKHKSTVRAICKRLGSKLLEEFLTEEHEIVSFIFRRTRLRSERIWYLDIIRIHGLVPHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CNIH4_PONAB
Sequence: MEAVVFVFSLLDCCALIFLSVYFIITLSDLECDYINARSCCSKLNKWVIPELIGHTIVTVLLLMSLHWFIFLLNLPVATWNIYRYIMVPSGNMGVFDPTEIHNRGQLKSHMKEAMIKLGFHLLCFFMYLYSMILALIND
What is the function of this protein?
Involved in G protein-coupled receptors (GPCRs) trafficking from the endoplasmic reticulum to the cell surface; it promotes the exit of GPCRs from the early secretory pathway, likely through interaction with the COPII machinery.
What are the official names of this protein?
Protein cornichon homolog 4, CNIH-4, Cornichon family AMPA receptor auxiliary protein 4.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum. Endoplasmic reticulum-Golgi intermediate compartment.
Protein: RL13_MYCLB
Sequence: MPTYAPKAGDTTCSWYVIDATDVVLGRLAAVAATLLRGKHKPTFAPNVDGGDFVIVINADKVAISGDKVQHKMVYRHSGYPGGLRKRTIGELMQKHPDRVVEKAIVGMLPKNKLSRQIQRKLRVYAGPDHPHSAQQPVPFEIKQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: YIDC_METPB
Sequence: MGNDKTNMFVAIALSLVVLLGWHYFVTGPASERQRQAVQSQTAQNTAPQSADGIPSPSPREGSPNAPVPGTVPGAAAQGPISREDALARSARVRIDTPALYGSIGLKGARIDDVSLKNYHETVSDESPRIVLLSPAGSANPYYAEFGWVGANAGPLPNGDTLWKADGDLLAPGKPLTLTWDNGQGLLFKRIVAVDDKFMFTVRDEVENSSANPVTLYPYSLVSRWGKPQTQGYYVLHEGLIGVLGSDGLQEYTYDKVGKEPAYGGAATQGKAWSNVTGGWVGITDKYWAAAAIPDQDKPFTGAFTERTDGATKIYQTSVRGDAVTVAPSASSATTQRLFAGAKEVNQINAYERDLGIKQFDLMIDWGWFWFLTKPMFRALDFFYHLLGNFGVSILLVTLILKIFFLPIANRSYVSMAKMKAVQPEMTSIRERYKDDRTKQQQAMMELYKKEKINPVAGCWPVLIQIPVFFALYKVLFITIEMRHAPFFGWIHDLAAPDPTSIMNLFGLLPFAAPDFIHLGVWPIIMGITMFIQMKMNPAPPDPVQAQVFAFMPIVFTFMLGSFPAGLVIYWAWNNTLSVIQQYIIMRRNGVKVELWDNLRGMFKRGNKSAAAKG
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL14_ECOLU
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL6_PELTS
Sequence: MSRIGRQPITVPAGVEVEIDGSTVKVKGPKGQLVKEMHRDMIIKYEDGRLIVERPANDKLHKSLHGLTRTLLNNMVVGVTAGFQKNLELVGVGYRASKQGNKLVLAVGYSHPVEIEPEAGLEIEVPAPTKISIKGVDKEKVGALAAAIRAVRQPEPYKGKGIKYEGEKIRRKVGKAGGKGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: FIMA1_ECOLI
Sequence: MKIKTLAIVVLSALSLSSTAALAAATTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLAQEGATSSAVGFNIQLNDCDTNVASKAAVAFLGTAIDAGHTNVLALQSSAAGSATNVGVQILDRTGAALTLDGATFSSETTLNNGTNTIPFQARYFATGAATPGAANADATFKVQYQ
What is the function of this protein?
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
What are the official names of this protein?
Type-1 fimbrial protein, A chain, Type-1A pilin.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: CA1C_CONPU
Sequence: SGCCKHPACGKNRC
What is the function of this protein?
Alpha-conotoxins bind to the nicotinic acetylcholine receptors (nAChR) and inhibit them.  This toxin inhibits rodent (alpha-1-beta-1-delta-epsilon > alpha-1-beta-1-delta-gamma) and human (alpha-3-beta-1) nAChRs heterologously expressed in Xenopus oocytes, but has minimal effect on human alpha-7 nAChRs.  Has no effect on the frequency of responses from the giant fiber (GF)-dorsal longitudinal and GF-tergo trochanteral muscle pathways in the D. melanogaster GF circuit (PubMed:28917942).  Has possibly a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (lacks the Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin PIC.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FIBC_LUMRU
Sequence: VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGLWQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNNNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQDPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGTCLPDYPSVYTRVSAYLGWIGDNSR
What are the official names of this protein?
Fibrinolytic enzyme, isozyme C, F-II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: VG02_GAHVM
Sequence: MTRGHRTALSPSPRATSLCTLMPCTAHTFAHAYCGACRGRGRLLPGQGSALRTATRPGQDSAPGRPARPRTDPGSPERRPAGTTCAGTGLERPPPRGARSVYSQSPARGSTAPTVVRAGPRVWERRRPRAPRRRGARGLPRGRRSRVALLGARGRAPHLPGAAEADRGELFAAAMAGAGRPRPAGEDPRADGGERTPR
What are the official names of this protein?
Uncharacterized gene 2 protein.
Protein: RS212_RHIL3
Sequence: MQVLVRDNNVDQALRALKKKMQREGIFREMKMRDYYEKPSQKRAREKAEAVRRVRKLARKRAQREGLVAAR
What are the official names of this protein?
30S ribosomal protein S21 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: COAE_PSEAE
Sequence: MTQPWILGLTGGIGSGKSAAAEHFISLGVHLVDADHAARWVVEPGRPALAKIVERFGDGILLPDGQLDRAALRERIFQAPEERRWLEQLLHPLIGAEIVQYLARAESPYAILVSPLLVESGQRQMTHRVLVVDTPEHLQLQRTMLRDKVSEEQVRSILQAQARRDERLKHADDVLVNDGDLSHLQREVERLHAFYLTLRGGRA
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O1618_CONCL
Sequence: MKLTYVLIVAMLVLVVCRADCFGRGGLCTWFDPSVCCSGICTFVDCW
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal6.18, O1_cal6.18.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: URED_ARTS2
Sequence: MSTTAAPEVELVETETPMGELALRVAVRGCRSVAAHQYHRGALRILRPHYLDDSGQVCYVVVNPGGAYLGADLYVIDVEVGDGAKLLLTTQSATKIYRTPGSFAEQRVCLRLGEGAQLELAPDQLIAYREASYRQNTRITVRPSSSLVMAEVVTPGWSPDGASFRYEELRLRNEIQVETPGGTGLLALDNLLIRPPLNDVTGMGFMEGYSHLGSLVVVDARVEQALADEFHALTAGHDACTGVSLTASVGGTTGLVLRSLSNSTEELNRLLGACTALLRERWYGQSPLNLRKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOA_MYCTO
Sequence: MAAATGGLTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGSLP
What is the function of this protein?
Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA).  It is the only aminotransferase known to utilize SAM as an amino donor (By similarity).
What are the official names of this protein?
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, 7,8-diamino-pelargonic acid aminotransferase, DAPA AT, DAPA aminotransferase, 7,8-diaminononanoate synthase, DANS, Diaminopelargonic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_BUCBP
Sequence: MIQKFLKKLFSDRNDRILQNIQTVISKINSMEKFFEKLSDLELKRNTTRFCYRLNNGETLDQLLPESFATVREASKRVFGMRHFDVQLIGGIILHQRCIAEMRTGEGKTLTATLPAYLNALQRKGVHIVTMNDYLAKRDAEKNRLLFNFLGLTVGINISGLSSKLKKQAYNADITYGTNNEYGFDYLRDNMVFCREDKVQRELNYALLDEVDSILIDESRTPLVISGSIEDVSDVYIKINEIIQVLFSQKQEDSDVFVGNGHFYIDEKQRQVFLTERGLVRTEEWLVSQNLIDKKESLYSSKNIVLMHNVVAALRAHYLFFKNVDYIVKNKKVIIVDEHTGRTMEGRRWSDGLHQAIEAKEGLKIRSENQTLASITFQNYFRLYKKLSGMTGTAITEAFEFRAIYNLDTVVIPTNTPMIRDDKPDLVYMTELEKFDAIIEDIKQCVSRNQPVLVGTISIQKSELISQKLLKLNIKHNVLNAKFHAQEAKIIAQAGKLRAVTIATNMAGRGTDIVLGGNLEFLLAHNNEKHTDEKMEDVIKKWNIEHNLVLKSGGLHIIGTERHESRRIDNQLRGRSGRQGDCGSSRFYLSMEDSLLRIFSSERMISIMRVIGVKKNEAISHPFVTKAILNAQQKVEYRNFEFRKQLLEYDNVSNEQRRVFYYQRNQIINSKDSNIGDIIKNIFCDVFLKIVNKFIKQKLLKQSQKILELESCLRDNFNIVCSISKKIRDNIVVYKSDLSKIVLKKVYQSYQCKINKYILKDVRKYERLVILDTLDYFWREHLASMEYLRQGIHLRGYGQKDPKQEFKRESFFMFLNMLSSSRYEIVSILLKKSISNNDFLKIYNHAKLVF
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: EP3A_HUMAN
Sequence: MTSSLKIWGILLALLCILCRLCVYSNNIYWREFIKLHYLSPSREFKEYKCDVLMREKEALKGKSFHMFIYSLWFKIQRACINEKGSDRYRNAYVWAPGALKVLECHWEKYNNRYTESRSFSYIEFHCGVDGYVDNIEDLRIIEPISN
What is the function of this protein?
Possible function in sperm maturation.
What are the official names of this protein?
Epididymal secretory protein E3-alpha, Human epididymis-specific protein 3-alpha, HE3-alpha.
What are the subcellular locations of this protein?
Secreted.
Protein: VP2_POVMK
Sequence: MGAFLAVLAEVFDLASITGLSVESILSGEALTTAELLQSHINNLVVYGGLTEAEALAAVEVTPQAFAALTSLFPNFPQALGALAATEFTATGALTVGAAVSAALYPYYWDYRTPVADLNMALQIWYPDLDILFPGALPFARFVNYIDPANWAADLYRAVGRYFWERVQAAGINFIEQQMETGRELAMRSVTSLSETLSQYFENARWAVSGLSTSLYHGLESYYSQLGLSPIQQRQLARNLGHPQPYRYDLYDAPQLKGQVSATYVTKVDPPGGANQRSAPDWMLPLLLGLYGDLTPSWKDTLEELEAEEDGSHSQKAKRRKTKA
What is the function of this protein?
Structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers.  Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane.  Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2 or VP3 nuclear localization signal (shared C-terminus).  Plays a role in virion assembly within the nucleus (By similarity).
What are the official names of this protein?
Minor capsid protein VP2, Minor structural protein VP2.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses capsid protein VP2 family.
What are the subcellular locations of this protein?
[Isoform VP2]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane. SUBCELLULAR LOCATION: [Isoform VP3]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane.
Protein: DXS_ECODH
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: ELAP2_HUMAN
Sequence: MLFRARGPVRGRGWGRPAEAPRRGRSPPWSPAWICCWALAGCQAAWAGDLPSSSSRPLPPCQEKDYHFEYTECDSSGSRWRVAIPNSAVDCSGLPDPVRGKECTFSCASGEYLEMKNQVCSKCGEGTYSLGSGIKFDEWDELPAGFSNIATFMDTVVGPSDSRPDGCNNSSWIPRGNYIESNRDDCTVSLIYAVHLKKSGYVFFEYQYVDNNIFFEFFIQNDQCQEMDTTTDKWVKLTDNGEWGSHSVMLKSGTNILYWRTTGILMGSKAVKPVLVKNITIEGVAYTSECFPCKPGTFSNKPGSFNCQVCPRNTYSEKGAKECIRCKDDSQFSEEGSSECTERPPCTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPCNPGFYNNGSSSCHPCPPGTFSDGTKECRPCPAGTEPALGFEYKWWNVLPGNMKTSCFNVGNSKCDGMNGWEVAGDHIQSGAGGSDNDYLILNLHIPGFKPPTSMTGATGSELGRITFVFETLCSADCVLYFMVDINRKSTNVVESWGGTKEKQAYTHIIFKNATFTFTWAFQRTNQGQDNRRFINDMVKIYSITATNAVDGVASSCRACALGSEQSGSSCVPCPPGHYIEKETNQCKECPPDTYLSIHQVYGKEACIPCGPGSKNNQDHSVCYSDCFFYHEKENQSLHYDFSNLSSVGSLMNGPSFTSKGTKYFHFFNISLCGHEGKKMALCTNNITDFTVKEIVAGSDDYTNLVGAFVCQSTIIPSESKGFRAALSSQSIILADTFIGVTVETTLKNINIKEDMFPVPTSQIPDVHFFYKSSTATTSCINGRSTAVKMRCNPTKSGAGVISVPSKCPAGTCDGCTFYFLWESAEACPLCTEHDFHEIEGACKRGFQETLYVWNEPKWCIKGISLPEKKLATCETVDFWLKVGAGVGAFTAVLLVALTCYFWKKNQKLEYKYSKLVMTTNSKECELPAADSCAIMEGEDNEEEVVYSNKQSLLGKLKSLATKEKEDHFESVQLKTSRSPNI
What is the function of this protein?
Functions as a regulator of the BMP signaling pathway and may be involved in epidermal differentiation.
What are the official names of this protein?
Endosome/lysosome-associated apoptosis and autophagy regulator family member 2, Estrogen-induced gene 121-like protein, hEIG121L.
What is the protein family that this protein belongs to?
Belongs to the ELAPOR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.