PharMolix/UniProtQA huggingface dataset:
Protein: TRUA_PYRAB
Sequence: MRVAFKIAYDGTRFHGFQRQPNLRTVEGEIIKALNNSGIMYSDFKSASRTDRGVSALGNVVAITTEDEKALNPMVLNARLEDVWILSAIEVPQDFHPRFWAKSKVYRYYLPSIGLEVEKVKECSQLFLGVHDFSAFSRVDGRDTVRSIDRIEVFTLGPILIIEIEAKSFLWEMVRRIVKALELCGLGRLSCEEIKEMLEGKFEKSKKVPPAPPEGLLLVDIKYEGIEFPLNDKALKKFKREVEERFRQKIMGAYLLWDMIQLL
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: HSP85_TRYCR
Sequence: MTETFAFQAEINQLMSLIINTFYSNKEIFLRELISNSSDACDKIRYQSLTNQAVLGDESHLRIRVVPDKANKTLTVEDTGIGMTKAELVNNLGTIARSGTKAFMEALEAGGDMSMIGQFGVGFYSAYLVADRVTVVSKNNDDEAYTWESSAGGTFTVTPTPDCDLKRGTRIVLHLKEDQQEYLEERRLKDLIKKHSEFIGYDIELMVEKATEKEVTDEDEDEAAATKNEEGEEPKVEEVKDDAEEGEKKKKTKKVKEVTQEFVVQNKHKPLWTRDPKDVTKEEYAAFYKAISNDWEEPLSTKHFSVEGQLEFRAILFVPKRAPFDMFEPSKKRNNIKLYVRRVFIMDNCEDLCPEWLAFVRGVVDSEDLPLNISRENLQQNKILKVIRKNIVKKALELFEEIAENKEDYKKFYEQFGKNVKLGIHEDSANRKKLMELLRFHSSESGEDMTTLKDYVTRMKEGQKCIYYVTGDSKKKLETSPFIEQARRRGFEVLFMTEPIDEYVMQQVKDFEDKKFACLTKEGVHFEETEEEKKQREEEKTAYERLCKAMKDVLGDKVEKVVVSERLATSPCILVTSEFGWSAHMEQIMRNQALRDSSMSAYMMSKKTMEINPAHPIVKELKRRVEADENDKAVKDLVYLLFDTALLTSGFTLDDPTSYAERIHRMIKLGLSLDDEDNGNEEAEPAAAVPAEPVAGTSSMEQVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock-like 85 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_SPHAL
Sequence: MNELATPDNPLRIGTRASPLAMAQAHMAAAALIAAHGLAMAALEIVPMTATGDRIQDRALAEVGGKALWTRELDAALDAGTIDVAVHSLKDVETLRDARFFLGAMLERADPRDRLVVREGIAAQKISELPHGARLGTSSPRRAAQVRRLRPDLDTVLLRGNVATRLAKLAAGEADATLLAAAGLERLGMHDIGAVQGTELLLPAASQGAIGIECRADDAATIALLAAIDHAPTHRAVAAERALLAVLGGDCRSPVAAYAEWQADGVLRLDAEIFSEDGADHVAGHVIVTDAGVVAALGHRLLAEAPPSIRRLFAT
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: NR1I2_HUMAN
Sequence: MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
What is the function of this protein?
Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds.  Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds.  Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones.  Response to specific ligands is species-specific.  Activated by naturally occurring steroids, such as pregnenolone and progesterone.  Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
What are the official names of this protein?
Nuclear receptor subfamily 1 group I member 2, Orphan nuclear receptor PAR1, Orphan nuclear receptor PXR, Pregnane X receptor, Steroid and xenobiotic receptor, SXR.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAD50_AQUAE
Sequence: MRPLKLEVKGFTVYKKPQVIDFTPLKFFVIQGKTGAGKTSIIDAITYALYGKVPRYGASVATKYVLSRGEKELKVALDFSLRGRNYRVERYYREFPEDSQVRVYEEGRRLNIKANEVEKWLFKISGLDYKTFTKVILLPQGEFDRFLKESSERKKILINLLGLEELEKVRQLASETFKNLEGKREALKKEYELLKDYTPTKKEVLEKTLKNLEEELKELKETEEKLRQELKKAEEKDSLERELSQVVTKLKELENLEKEVEKLREKLEFSRKVAPYVPIAKRIEEIDKKLTELKVRKNKLTKELAVLKDELSFAQEELNRIEAEKEKFKEEKEREKELEHRLKKLQEIKEILKELSQLSSSLKEKEREYEQAKQEFEDLSERVEKGKKLVAETEEKLEKIKELFSEEEYTSLKMKERLLVELQRKLKELKEKEGQLENLTQKYKEKKKVHEKVLNELKELERELKERELHYHAHMVASYLSPGDTCPVCGGIYRGKALENVDAEGISELKHAKELKEKEEREIDTTLKLYAQKINSLKEEMEKLRNEVEELRKEIPENLKERIKKLEELRIEKEKLEHKLNKYRKALEDRQKQKEEAQAKLHKAQTELELLKEKIREKSRLVKEFKELYRVERLEDYEESLKEEINYINSKLQEIEEKEKKLRKHFEELSSRKSKLEGELSALNESINSLEEERKEKLKELANIYEVAKSPREVVELYLGDKEAELERKIKEFEESFQSLKLKKSEIEEKLKEYEGIRELSDIKGEYESVKTQLEEKHKKLGEVKRELEHLGERLKRKEELQKEISELEKKLEVYRVISNDFRGDRFQKYVSEIMLQKVVDRASEYFYKFTGNYFFELERATKGRDKDIVVVESSTSQRRPVSSLSGGETFLASLSFAFAVSDLLSGSANLESLFIDEGFGSLDQDMRERVSEILEAIKTNVNKMIGIVSHIPDFAERFTERIVVEKKGDYSEVRVIY
What is the function of this protein?
Involved in DNA double-strand break repair (DSBR).  The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity.  Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site (By similarity).
What are the official names of this protein?
Probable DNA double-strand break repair Rad50 ATPase.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
Protein: FLGN_BUCAI
Sequence: MNNLIDTIKKIENILYSLERILKQECHNLLKSKTSNEEILELIKRKKILFKKLIILSQDRLCLEKEYNIFPPYESNNKLNNYWKKIINTCLILRKLNLKNKIIMNKKFYLNQRFLELSSSYKKSVTYNLDGNLEI
What is the function of this protein?
Required for the efficient initiation of filament assembly.
What are the official names of this protein?
Putative flagella synthesis protein FlgN.
What is the protein family that this protein belongs to?
Belongs to the FlgN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_XANCP
Sequence: MSEQLPLLIELGTEELPVKALPGLAQAFFDGVLAGLEKRGVAVTRGDAKPLSTPRRLAVLLPGVATEQPEQRSEVLGPYLNIALDAEGKPTRALAGFAAKAGIDWTALERTSDAKGERFVHRAVTPGAQAAALLPEILREAIAAMPIPKPMRWGAHEYAFARPVQWLVLLFGDTVIPAELLGVRGDRITRGHRFMHDGDIALAAPGDYIDALRAAHVLVDADARRARIVEEVDAAARQAGGSARISDDNLEQVVNLVEWPSAVLCSFERAFLAVPQEALIETMEINQKFFPVLDDGGKLTEQFIGIANIVSKDVAEVAKGYERVIRPRFADAKFFFDEDLKQGLEAMGAGLASVTYQAKLGTVADKVARVAALAEAIAPQVGADPVQARRAAELAKNDLQSRMVNEFPELQGIAGRHYAKAAGEPSEISLAIDEAYQPRFAGDDIALSPLGKVLAIAERLDTLAGGFAAGLKPTGNKDPFALRRNALGLARTVIESGFDLDLPKLIDVGLASLPDAVKPHADRNTETVRADLYDFILDRLKGYYADKGVAATHFNAVAELKPASLYDFDRRIDAIGIFATLPEAEALAAANKRIRNILRKVEGEIPGDIDTTLLREPAEEALAEAVEAAIGDTGDALHRHDYVAVLARLARLRPQVDAFFDGVMVNADDPQLRANRLALLKKLGDRLGSVAAIEHLSS
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK2_RHYMA
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, Lem-PVK-2, RhyMa-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FMR1_DROME
Sequence: MEDLLVEVRLDNGAYYKGQVTAVADDGIFVDVDGVPESMKYPFVNVRLPPEETVEVAAPIFEEGMEVEVFTRTNDRETCGWWVGIIKMRKAEIYAVAYIGFETSYTEICELGRLRAKNSNPPITAKTFYQFTLPVPEELREEAQKDGIHKEFQRTIDAGVCNYSRDLDALIVISKFEHTQKRASMLKDMHFRNLSQKVMLLKRTEEAARQLETTKLMSRGNYVEEFRVRDDLMGLAIGSHGSNIQAARTVDGVTNIELEEKSCTFKISGETEESVQRARAMLEYAEEFFQVPRELVGKVIGKNGRIIQEIVDKSGVFRIKVSAIAGDDEQDQNIPRELAHVPFVFIGTVESIANAKVLLEYHLSHLKEVEQLRQEKMEIDQQLRAIQESSMGSTQSFPVTRRSERGYSSDIESVRSMRGGGGGQRGRVRGRGGGGPGGGNGLNQRYHNNRRDEDDYNSRGDHQRDQQRGYNDRGGGDNTGSYRGGGGGAGGPGNNRRGGINRRPPRNDQQNGRDYQHHNHTTEEVRETREMSSVERADSNSSYEGSSRRRRRQKNNNGPSNTNGAVANNNNKPQSAQQPQQQQPPAPGNKAALNAGDASKQNSGNANAAGGASKPKDASRNGDKQQAGTQQQQPSQVQQQQAAQQQQPKPRRNKNRSNNHTDQPSGQQQLAENVKKEGLVNGTS
What is the function of this protein?
Polyribosome-associated RNA-binding protein that plays a role in neuronal development and synaptic plasticity through the regulation of protein synthesis of mRNAs (PubMed:11046149, PubMed:11733059, PubMed:12368261, PubMed:17178403).  Acts as an mRNA regulator by mediating formation of some phase-separated membraneless compartment: undergoes liquid-liquid phase separation upon binding to target mRNAs, leading to assemble mRNAs into cytoplasmic ribonucleoprotein granules that concentrate mRNAs with associated regulatory factors (PubMed:35165263).  Mainly acts as an activator of mRNA translation: promotes translation of stored mRNAs in oocytes (PubMed:30115809).  Can also act as a negative translational regulator of specific mRNAs (PubMed:11733059, PubMed:17178403).  Represses translation of the microtubule-associated protein futsch mRNA to regulate microtubule-dependent synaptic growth and function (PubMed:11733059).  Localizes to specific N6-methyladenosine (m6A)-containing RNAs as part of a complex with the m6A reader Ythdf and thereby regulates axonal growth in the mushroom bodies and neuromuscular junctions (PubMed:33428246).  Specifically recognizes and binds a subset of N6-methyladenosine (m6A)-containing mRNAs in embryos, promoting formation of a phase-separated membraneless compartment that mediates degradation of maternal mRNAs (PubMed:35165263).  May also be involved in microRNA (miRNA)-mediated translational suppression as part of the RNA-induced silencing complex (RISC) (PubMed:12368261, PubMed:14508492).  Required for stability of the central pair of microtubules in the spermatid axoneme (PubMed:15183715).  Regulates photoreceptor structure and neuromuscular junction (NMJ) neurotransmission in the eye (PubMed:11733059, PubMed:17178403).  During embryogenesis, involved in germline fate determination (PubMed:16949822).
What are the official names of this protein?
Fragile X messenger ribonucleoprotein 1 homolog, FMRP, dFMR1.
What is the protein family that this protein belongs to?
Belongs to the FMR1 family.
What are the subcellular locations of this protein?
Cytoplasm. Perikaryon. Cell projection, neuron projection. Synapse. Cytoplasm, Stress granule. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Note=Localizes in the neuronal soma and cell processes, and in pre- and postsynaptic neurons, as well as in postsynaptic muscles.
Protein: NQRD_YERE8
Sequence: MADSKEIKRVLLGPLFDNNPIALQILGVCSALAVTTKLETALVMTLAVTLVTAFSSFFISLIRNHIPNSVRIIVQMVIIASLVIVVDQILRAYAYEISKQLSVFVGLIITNCIVMGRAEAYAMKSPPIESFMDGIGNGLGYGVVLVLVGFVRELIGSGKLFGVTVLETVQNGGWYQPNGLFLLAPSAFFIIGLLIWGLRTLKPAQIEKE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELD_AQUAE
Sequence: MVELLKLVRSSGUAAKVGPGDLQEILKGFNIYTDESTLVSIGDDAGVYEHNGIIWVYTVDIITPVVNDPYLWGAISTANALSDVYAMGGIPVNALAISCFNNCELDIEIFREVIRGALDKLREAKTVLLGGHTIDDKEPKFGLSVAGICPEGKYITQSGAQVGQLLILTKPIGTGILIKGLKEGILKEEDINEAIENMLALNDKARNLMLSLDATACTDVTGFGLLGHAWNICKNSNIGARIFFEKVPYYQLSENLVKKKIYPKGAIENLNFVKNYLKSNLDNWKLILLSDPVTSGGLLFTINKEKLEKIDETAKELEVNYWIIGETIAENVLEVL
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: ATG3_YEAS7
Sequence: MIRSTLSSWREYLTPITHKSTFLTTGQITPEEFVQAGDYLCHMFPTWKWNEESSDISYRDFLPKNKQFLIIRKVPCDKRAEQCVEVEGPDVIMKGFAEDGDEDDVLEYIGSETEHVQSTPAGGTKDSSIDDIDELIQDMEIKEEDENDDTEEFNAKGGLAKDMAQERYYDLYIAYSTSYRVPKMYIVGFNSNGSPLSPEQMFEDISADYRTKTATIEKLPFYKNSVLSVSIHPCKHANVMKILLDKVRVVRQRRRKELQEEQELDGVGDWEDLQDDIDDSLRVDQYLIVFLKFITSVTPSIQHDYTMEGW
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8.  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8.  The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme ATG3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
Protein: WHIA_STRAW
Sequence: MAMTAAVKDEISRLPVTRTCCRKAEVSAILRFAGGLHLVSGRIVIEAELDTAMAARRLKRDILEIFGHSSELIVMAPGGLRRGSRYVVRVVAGGDQLARQTGLVDGRGRPIRGLPPQVVSGATCDAEAAWRGAFLAHGSLTEPGRSSSLEVTCPGPEAALALVGAARRLSIAAKAREVRGVDRVVVRDGDAIGALLTRLGAHESVLAWEERRMRREVRATANRLANFDDANLRRSARAAVAAGARVQRALEILADEVPEHLAAAGRLRMEHKQASLEELGALADPPLTKDAVAGRIRRLLAMADKRAQDLGIPGTESNLTEEMADNLAG
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: CBP_MESMA
Sequence: IFGGTFAKNGEYPWMVVIDLPEFACGGVLISKKFVLTAAH
What is the function of this protein?
Binds in a dose-dependent manner to the breast cancer cell line MCF-7.
What are the official names of this protein?
Serine proteinase-like BMK-CBP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRD_AZOSB
Sequence: MLYDIARPFLFSLDAETAHEFTLAALNLAGRTLPAGKPEAADAVRVMGIDFPNRIGLAAGLDKNGEAIDGLARLGFGFIEIGTITPRPQPGNPRPRLFRLPEVRGIINRMGFNNHGVDTLVANVKAARFKGVLGINIGKNFDTPIENAADDYLACLDKVYPLASYVTVNISSPNTKNLRQLQGESELDDLLGRLKSAQQRLADQHGRYVPLTLKIAPDLEAAQITNIADALRRHRIDAVIATNTTISRDKVQGVRFAEQQGGLSGAPVFEASTAVVAQLATALGGELPIIAAGGVMDTRSARAKLEAGASLVQLYSGLIYRGPCLVRECVRATADFPR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: COBT_PSEPG
Sequence: MTQAWWRDACHPLDNDAMDQAHARQQQLTKPAGSLGQLEGLAIQLAGLQGCERPILDQVAITIFAGDHGVVEEGISAYPQAVTGQMLRNFVGGGAAISVLARQLQASLEVVDLGTIDAQLELPGVRHLRLGAGTANFACQPAMTENQLQAALQAGRDSALRAAEQGAQLFIGGEMGIGNTTAAAALASVLLSCPAAQLSGPGTGLDNAGVRHKAEVIERALRLHGLRAENPLQALGCVGGFEIAALAGAYIGCAQAGVAVLVDGFICSVAALVAVHLNPQCRAWLLFAHQGAEPGHKALLAALQAEPLLALGLRLGEGSGAALAVPLLRLACALHGQMATFAEAAVADRPA
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: NUOA_ECODH
Sequence: MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARSKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSMO1_PIG
Sequence: MATNQSISIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFFFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQFPLICGTYYFTEYFSIPYDWETMPRWYIALARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKIHHEFQAPFGMEAEYAHPLETLILGTGFFIGIMLLCDHVILLWAWVTVRLIETIDVHSGYDIPLNPLHLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDAQYNAYNEKRKKAEKKTE
What is the function of this protein?
Catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, which can be subsequently metabolized to cholesterol.
What are the official names of this protein?
Methylsterol monooxygenase 1, C-4 methylsterol oxidase, Sterol-C4-methyl oxidase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: URE3_KLEPN
Sequence: MELTPREKDKLLLFTAALVAERRLARGLKLNYPESVALISAFIMEGARDGKSVASLMEEGRHVLTRKQVMEGVPEMIPDIQVEATFPDGSKLVTVHNPII
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBLP_LEIMA
Sequence: MNYEGHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTVISWKANPDRHSVDSDYGLPNHRLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLSTGEQLFKINVESPINQIGFSPNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPSECISIAWSADGNTLYSGHKDNLIRVWSISDAE
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-like protein, Antigen LACK.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
Protein: GLUCL_HYDCO
Sequence: HADGIYTSDVASLTDYLKSKRFVESLSNYNKRQNDRRM
What are the official names of this protein?
Glucagon-like peptide, GLP.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEF_STRT2
Sequence: MDAQTKIIRASHMIDMNDIIREGNPTLRAVAEDVTLPLSDEDIILGEKMMQFLRNSQDPVIAEKMGLRGGVGLAAPQLDISKRIIAVLVPNPEDAKGNPPKEAYSLQEIMYNPKVVAHSVQEAALGNGEGCLSVDRDVPGYVVRHARVTIEYFNKEGEKKRIKLRGYDSIVVQHEIDHTNGIMFYDRINKDNPFTIKDGLLIIE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: MOAC_PSESM
Sequence: MLTHLDSQGRANMVDVTDKAVTSREAVAEALVRMLPATLQMIVSGGHPKGDVFAVARIAGIQAAKKTSDLIPLCHPLMLTSIKVHLAAEGDNAVRITASCKLSGQTGVEMEALTAASIAALTIYDMCKAVDRGMVIESVRLLEKLGGKSGHFIADDAQVAP
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RS21_SALPK
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: VM3_PROJR
Sequence: YLNNFRYLYIRHDREACTCHANSCIMSAYFSNSHVQYENYINDCKPQCILNELHSWVECESGECCEQCRSECDIAESCTNGQPLHNFGYCYNGNCPIMYHQCYLYCYNSLGNQFPCVPYYTPR
What is the function of this protein?
Snake venom metalloproteinase that has high hemorrhagic activity and degrades the alpha-chain of fibrinogen (FGA), leaving the beta- and the gamma-chain intact.  It may also inhibit platelet aggregation.  Cleaves insulin B chain at '25-Phe-|-Val-26', '26-Val-|-Asn-27', '29-His-|-Leu-30', '30-Leu-|-Cys-31', '33-Ser-|-His-34', '35-Leu-|-Val-36', '40-Tyr-|-Leu-41', '41-Leu-|-Val-42', '42-Val-|-Cys-43', '43-Cys-|-Gly-44', '44-Gly-|-Glu-45', '46-Arg-|-Gly-47', '47-Gly-|-Phe-48', '49-Phe-|-Tyr-50' and '52-Pro-|-Lys-53' bonds.  Also cleaves human prothrombin (72 kDa) and activation fragment F1 (27 kDa) of activated human prothrombin, to generate two new proteins of 68 and 23 kDa.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like jerdohagin, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COBS_DESVM
Sequence: MKLASLLAAQWRALVLSTGFLTRLAPARAATDAEMAAGVAHYPLVGLLAGLVCAGPFLLGLLAGHPWVQALGYAALLLWATRGLHWDGWADLMDAWGSSATGDRFWDILKDSRIGAFGVLGIVFGVLGQVVLAHEVITLGRAGALVWAPVLGRAACVVLAACVPPGTRSTLGRLTSAGATHMTVLFCAGVTAATGVALAGPPAVLAAALPCACAVVWLTALARREGGLNGDFLGACIIQGELSALLGTILA
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.