PharMolix/UniProtQA huggingface dataset:
Protein: SYM_LACPL
Sequence: MAETKPTYYITTPIYYPSGKLHIGNSYTTIACDTLARYKRAMGYDVYFLTGTDEHGLKIEEKAEKLNTDPKSYVDGMAKQIKDLWQLLEISNDKFIRTTDDYHERAVQEIFDRLLKNGDIYLGEYEGWYSVDDEEYFTETQLAEVFRDDNGKVIGGKAPSGHEVELVKEQSYFFKMSKYADWLLDYYQSHPDFIEPANRMTEMINNFIKPGLEDLAVSRTSFTWGVPVKSDPKHVVYVWIDALTNYITALGYATGDSEDLFNKFWPADVQMVGKEIVRFHTIYWPIILHALGLPLPKKVFGHGWLLMKDGKMSKSKGNVIYPETLVERYGLDALRYYLVKAMPYGNDGLFTPEDFVARVNYDLANDLGNLLNRTIAMINKYEDGQLPAFKAGVTEFDADLEATAATTIKNFNACMDSLHLSDALAEVWKLVSRTNKYIDETAPWQLAKSDDANDADKLASVMAHLAASLRVIASLISPVMTHAPKEIFTQLGLDPATLAIADLQLADLPAGAQVVAKGTPIFPRVDMDAEVEFLKGKMTKSDKQKGRKAMENAKHEAEVEQGWNPAETNLNLTKPAITIDDFDKVELKVAEVITVQKLKGADKLLQFRLDAGDADHRQILSGIAKWYPEPEELIGKKVIIVGNLKPRKLRGEMSQGMLLSAEHDGQVQLITVPDNMVNGSLIS
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_PSET1
Sequence: MKKNVTELYKTIDYIFADQGLLEQAMTHRSHKGQHNERLEFLGDSILSFVIANALYAKFPKAREGDLSRMRSTLVRGQTLAEFGLEFGLGDYLRLGPGELKSGGFRRESTLADAVEAIIGAVFLDSDIERCGELILSWYEERLNAISPGLNQKDPKTLLQEHLQARKLSLPGYTVVDTKGQAHNQTFTVECIVDGMDSIISVGSSRRKAEQKAAEKALKILKNEP
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_PSEF5
Sequence: MIPELPHAQLDWDDQGRPRSRVFDDVYFSSESGLDETRHVFIEQNRLGQRFAALADGERFVIGETGFGTGLNFLCAWQLFQQQAPTGARLHFVSVEKYPLSPADLQRALALWPELASFSAPLLEQYVAVHGGFQRIVLEGGRVILTLLIGDALEQLPQLDAQVDAWFLDGFAPAKNPDMWTAELFAELARLAAPGSTISTFTSTGWVRRLLNSAGFKMKRTPGIGHKWEVLRGEFLGWPEDAPAPARARPWFARPALGEKTALVIGGGLAGCASAASLAARGWQVQLLERHAELAREASGNPQGVLYLKLSAHGTALSQMILSGFGYTRRQLEHLQRGQDWDGCGVLQLAFNAKEAERQAQLAAAFPADLLHLLDQPQAQARAGIGLEHGGLFYPEGGWVHPPALCQWQASHPRIQVLAHREVLELRRVDEQWQAWDGDRMLASAAVVILAGAAEIKRFPASADLPLKRIRGQITRLPQTAQSQSLATVVCAEGYVAPARLGEHTLGASFDFKSQDLTPTSAEHAGNLEMLREISSDLLQRLGAEQLPLDSLQGRAAFRCTSPDYLPIVGPLADPLAFAETYAALGKDARQVPDLPCPWLDGLYINSGHGSRGLITAPLSGELLAAWLENEPLPLPRSVAEACHPNRFALRRLIRGKA
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_ECOLC
Sequence: MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBA4_MAIZE
Sequence: MRECISIHIGQAGIQVGNACWELYCLEHGIQADGQMPGDKTIGGGDAEFDEGEDGDEGDEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-4 chain, Alpha-4-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ATPF_PARP8
Sequence: MNLNATLFAQMVVFLILAWFTMKFVWPPLINALDERSKKIADGLSAAEKGKLELEAAHKRVDQELSQARNEGQQRIADAEKRAVAVADEIKAQAQAEAARIIAQAKADADQQIVKAREALRGEVAALAVKGAEQILKREVDQAAHADLLNQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRPB_FRAP2
Sequence: MSKLNAYFGEYGGQFVPQILVPALDQLEHEFIKAQADESFKQEFKELLQEYAGRPTALTKTRNIVKNTKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLDLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVHSGSATLKDACNEALRDWSANYNKAHYLLGTAAGPHPFPTIVREFQRMIGEETKQQILAKEGKLPDAVIACVGGGSNAIGMFADFIDETSVQLIGVEPAGKGIETGEHGAPLKHGKTGIFFGMKAPLMQNSDGQIEESYSISAGLDFPSVGPQHAHLLAIGRAEYASATDNEALDAFKLLCKKEGIIPALESSHALAYALKLAYENPDKEQLLVVNLSGRGDKDIFTVHDILKEKGEM
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: DAPF_SHEB5
Sequence: MIQFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLADRNFGIGFDQLLLVEPPYDPDLDFHYRIFNADGTEVEQCGNGARCFARFVRNKGLTNKSKIRVSTSSGKMTLRLERDGTVTVNMGVPILEPSQIPFKAKKPEKTYLLQTPMQTFLCGAASMGNPHCVLDVEDVASASVAEIGAMLTKHERFPRGVNVGFMQVVDSGHIKLRVYERGAAETLACGTGACAAVVVGQVQGKLGQQVRVDLPGGTLTINWEGEGKPLWMTGPAQHVYDGQIQL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAKLN_ARATH
Sequence: MSNESTNCSFFLNLFMLLLLLIFYSADACQRECGGISIPYPFGIGKDCCLEKYYEIECRNTTSRKLVPLLSFINKEVVSISLPSADSHFAYEVSDQERHESFGLVRVKFPITSAGCFNDGKESGGGSKMNFTGSPFFIDRSNSLIAAGCNSKVSLMYIKPKMVGCELSCNTSKDSYSNSIPFVEAGCSSNVLPYSQDQGCPEEIAEETGCNGIGCCQASLPNEPQQVIGIRTENNDGNSTTKVECTVSAFLTDEIYALPKATKTEHLLAKRYATVSLGWVIQTSNRSFLDSLALACKDREDYRNTTNLERKCTCGRITISETSYANCGCTYGYTGNPYVLNGCKDIDECKVKFEYCGKTETCVNFEGGYRCVRDKTKAIMIGAGTGFGVLVLVGGLWWLRKFLIKRRITKRKKKFFKRNGGLLLLQELNTREGYVEKTRVFNSRELEKATENFSENRVLGHGGQGTVYKGMLVDGRTVAVKKSKVIDEDKLQEFINEVVILSQINHRHVVKLLGCCLETEVPMLVYEFIINGNLFKHIHEEESDDYTMLWGMRLRIAVDIAGALSYLHSSASSPIYHRDIKSTNILLDEKYRAKVADFGTSRSVTIDQTHWTTVISGTVGYVDPEYYQSSQYTEKSDVYSFGVILAELITGDKPVIMVQNTQEIVALAEHFRVAMKEKRLTDIIDARIRNDCKPEQVMAVAKVAMKCLSSKGKKRPNMREVFTELERICTSPEDSQVHNRIDEEEEEEEEEEEVVTTINRGDSWSISVTAPALSIVASSPSSDVEPLFPRLTW
What is the function of this protein?
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.
What are the official names of this protein?
Wall-associated receptor kinase-like 18.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PP329_ARATH
Sequence: MRSGGNKYLASLLRCYRDERCKLSGKVIHGFIVRMGMKSDTYLCNRLLDLYIECGDGDYARKVFDEMSVRDVYSWNAFLTFRCKVGDLGEACEVFDGMPERDVVSWNNMISVLVRKGFEEKALVVYKRMVCDGFLPSRFTLASVLSACSKVLDGVFGMRCHGVAVKTGLDKNIFVGNALLSMYAKCGFIVDYGVRVFESLSQPNEVSYTAVIGGLARENKVLEAVQMFRLMCEKGVQVDSVCLSNILSISAPREGCDSLSEIYGNELGKQIHCLALRLGFGGDLHLNNSLLEIYAKNKDMNGAELIFAEMPEVNVVSWNIMIVGFGQEYRSDKSVEFLTRMRDSGFQPNEVTCISVLGACFRSGDVETGRRIFSSIPQPSVSAWNAMLSGYSNYEHYEEAISNFRQMQFQNLKPDKTTLSVILSSCARLRFLEGGKQIHGVVIRTEISKNSHIVSGLIAVYSECEKMEISECIFDDCINELDIACWNSMISGFRHNMLDTKALILFRRMHQTAVLCPNETSFATVLSSCSRLCSLLHGRQFHGLVVKSGYVSDSFVETALTDMYCKCGEIDSARQFFDAVLRKNTVIWNEMIHGYGHNGRGDEAVGLYRKMISSGEKPDGITFVSVLTACSHSGLVETGLEILSSMQRIHGIEPELDHYICIVDCLGRAGRLEDAEKLAEATPYKSSSVLWEILLSSCRVHGDVSLARRVAEKLMRLDPQSSAAYVLLSNTYSSLRQWDDSAALQGLMNKNRVHKTPGQSWTTYGNDLDSGFRK
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g20770.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: SOX2_XENLA
Sequence: MYSMMETELKPPAPQQPSGGNSNSASNNQNKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGANAMTSGVGGSLGAGVNQRMDTYAHMNGWTNGGYGMMQEQLGYPQHPGLNAHNAPQMQPMHRYDVSALQYNSMSSSQTYMNGSPTYSMSYSQQGAPGMSLGSMGSVVKSESSSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPESAAQSRLHMSQHYQSASVAGTGINGTLPLSHM
What is the function of this protein?
Transcriptional activator (By similarity).  Functions as a switch in neuronal development, participating in the differentiation of embryonic neuroectodermal cells into neural tissues by making the ectodermal cells responsive to FGF-neuralizing signals.  Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity).
What are the official names of this protein?
Transcription factor Sox-2, XSox2, XlSox-2, SRY (sex determining region Y)-box 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: DOP1_YEAST
Sequence: MSLPLKPLTIDSNNKQLDSKQKKFRANVERALERFDSVTEWADYIASLGTLLKALQSWSPKFQNVRYYVPSPYQVSRRLTSSLSPALPAGVHQKTLEVYTYIFEHIGLETLATECNIWIPGILPLMTYASMSVRSHLIELYDNYILLLPQTTLRLLIRPLISSLLPGIDDESNDFLPLTLKLIETLQENLDDDSLFWQTLFLVMTANKGRRLGGLTWLTRKFPSLNAVPHLVNKIKMEAEENPSETETNDSHLDRKKRKEEAFKVLLPAAKDLVTPEPGLLIRCLVGCLEDENDILIKRSVLDLLLQRLRLDSPVLNVLITSEDKKLLIMSCCRTTLSKDMSLNRRIWNWLLGPTAGGMLNNNGGNSMEYTTSVKSANEESNVYFTKYGLSALLEGLSDLLSEEESVLTAFRISMAVMDRWEIGSLVIPELFIPLLYSSEKFKQNEQIMKTARTFFDNTETNIIWGKLFQELEDIKNLKILDFVLTNFNIGNDEEIIVRHLPLILLTLLALPSNDKDFDNIYKLQKFSLYNKLLNYIPERALLPLSHSKLKHDDEVSCEELLAKIRGFYTNVSNPSSILEKENIAERLPPFTTEDLTFLIADLIQKKLLSSLWDLENINESSKLFIAIFEKIPESEELKGRSHISWSDKKITQSIFEAIPRLCESNNDAKSEEIVGIVEIFGNYLYSRMEFIESMKLLKVVMMAVWKSLKDPRHQILGVKNLKTLNRFIPSKFIESALVYTFVEEEDISERLSVLDLLWTQLDSDSNLIRRPLELILGELFDDQNPFYLTVSKWILSILNSGSASRLFYILTDNILKVNRLEKERLDERDDLDMLTYEFQMLAYVLKTNNGRTRKVFSTELTSIKSSTIWKNEDVSTYKSLLLVTLMRFLNIKSNTHAKSIRSALILLDILLDGTEQNFKDIVIFLLQMSSKYIAEEGIEPELIAVSLLDIVSKVLRLSHDNGIKLDIFDDNAAHLKYIDFLVTSVSNMKSPLIVTAYVKLLSESIVYFENSIFRMILPLSASLVQCVQRLFLLEKREGGYYQPIALLLGGLEELLEISHGYLVTEEREGYFSGSNLKGDFIQSVVSNVFSSDSSNEESKIQGERDVILQSFRQVISCCLDIWYWAHNISCKSNDDSSLDATNHNSYKFKFRSKKLLETLFLLEPLELLENLISIRSDNTTVTLVHVLDGNKPAITIPHLLYGVIIRYNRTASVKFSNRDGSRSSTTKLTKGEPSMLKRLSGESIIAFLFNYVDSVENSAMEEFYGDFLLFFREVATNYNLYSDVSLSILKLVALISGKVSKTQFGEQKRVRREISDVFFKYLPNAFINFTNLYRGHPDSFKDLEFVVWRVQYIVNDQIGGDKFNTTLATIVNQCLTPYIKPKSEKTIPGYVLELAAVVSHLGSKVKSWRLLIAELFQNDKKLSVIGSDQTWEKIIYEWSIYPENKSKILNDLLLEIGSKRSSVTPTLITFNLGSDSEVEYKCQNLLKISYLLMVSPNDAYLLHFSSLISCIFHYLVSKDIKLKGSCWILLRVLLLRFSESHFNDYWSMISYCLQTNLQEFYESLQIQSEVDPQTILQVCKTLDLLLLLNMEGFTSTNEWIFVIDTINCVYKTNSFVALVDEIAEFKDYEITKTDDLELPTTLKDGLPLLRGIHKIERHTQLRSFFQNLSYLHYEKVYGLGSVDLYGCGEDLKKDILS
What is the function of this protein?
Involved in cellular morphogenesis.  Required for traffic between late Golgi and early endosomes, and for the normal structure and organization of the endoplasmic reticulum.
What are the official names of this protein?
Protein dopey.
What is the protein family that this protein belongs to?
Belongs to the dopey family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Note=Late Golgi.
Protein: SYFA_METM7
Sequence: MELHNDEKRLLKAFQDSNKKIMNLEELSEYIEKEKVMRAAFWLSGRDFLEIIENKTRVCELTELGKNSLDSEIPERKVANYIKENNLESIPIKDLSKILEKDETGAALGNLKKKELVTIDKGNIVFKNLDYKDNEEEVLKKVSEDFNLSNYSEDEVKIIENLKKRGFLKINEVVDRSFELKSAGIDFIKNPIEIKEEITQLTREMIVSGKWNDYTIRPYDAKIPTEEIYPVKAHPMSKIIQEVNEVLISMGFKEVKSQIVQTEFWNFDTLFEPQDHPARDMQDTFFVKYPNTGIVPKDLLEKVKGIHECGTIGSEKISKGWCYKFDEKVSERTVLRTHTTVSSIKYLASLSETERENPQKVFCIDRVFRNETIDYKHLPEFYQCEGIVMAEDVNFDNLVGVLKEFLRKLGFEKVRIRPAYFPFTEPSLEAEVYMEGKGWLELLGAGVFRPEVLEPFGIKKPVLAWGIGLSRLAMLRLGLTDIRELHKNDIEWLKKTAVSEK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJ9J_YEAST
Sequence: MKVEKSSKGLEVLVRTQEDDLEGFSFLEIMDRVDPLPLDFENYKNFKEGIYYMCTHDGTKIGFVLKFAINEMETVCSEIFEETFQLDESRHELRFKSEDFDHRNNLIDQLARKMYLESSLSGVKGWRNEKYAVWVNKKPYVLVERAVAGVLGIITYGIHINGYVLDPKSKKVQFWVPRRSKTKQTWPLMLDNIIAGGLGYPYGIYETVLKESMEEANLEKSVIEDNIKATGSVSYLYFTGDISVTKFNKESDFIVGEVQYVYDLKLSEDIIPKPNDGEVESFNLFSLQETINALRKKEFKPNCALVMVDFLIRHGYITPENEPNYLELVTRMHRRLPFPTLN
What are the official names of this protein?
Uncharacterized protein YJR142W.
Protein: CO3_HUMAN
Sequence: MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN
What is the function of this protein?
Adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance.  Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways.  Ligand for C5AR2.  Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2 (PubMed:8376604, PubMed:2909530, PubMed:9059512, PubMed:10432298, PubMed:15833747, PubMed:16333141, PubMed:19615750).
What are the official names of this protein?
Complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1.
Protein: Y976_TREPA
Sequence: MVLTQKNLVKRTTESTETEAVSDLLVSELLILGLSLPALLRPFSRQSRKISAIPLLPVLALSVGALTVLGQGLTLDLTLSLVSSSVVCLTELPRLVAFSQGIPNDLYSAGARIARVLLLVAGVFTLVIVCLCAPEPGYRPSRSVVRSSFSLRLGNTKVNAGLLLSLANPYETSHLDNPSAPHPSENPQSRAHPKQNPVGVNVVVLKNTPQSAHRAHPETLELMLAERGYTVFVPYQDAYSPSYSAASLAAPMRTSPGVVLLSSALRGVPFDVPTPYVSRRANTIDAATFEDAHVPALFPALFALCRHAPTFVYAESAHEVMLSRFLQQQPHACAGVFFVLPDSAARGPHHAPAVQGAPPPVDTAGVASAVRGASRTLPAVYRQYVHAAEAAWAELASTDILAAYLAGLPRDRHRTRLQARATQVDQWIRAQLHLSEPVLPHAQALSHHTVHAGGTYDRT
What are the official names of this protein?
Uncharacterized protein TP_0976.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPLB_DICDI
Sequence: MGITSSKPVSGSNTTTNSPTNQKAISEKKQKPKRTNKRNLSTDSKSSTCSSPTNNYLADELVVDLNSMEIEGADSIQYSGHSHSSSMTNSMTNSMRNSANEKQLQQKQQQPQQQPQQQQPQPHQSHDDLNSSALDQDDGEFNNNFENESEVESISSSSINNNNTNNNSNNNNNNNNNNNNNNNNNNNIPSISNISNNNINNNINNNNNNNSCKQKNSKNKKNKNKNNNNKNSSSSNERPYSISYDNEGSTTKSNSTLSLYSNISNLHSITSHSIQDASIVCENCNHHMTKPIHLLSLSLEPTSAASLDIHRNGNFSITLASNSRSSSPATILQQNNKHFLINSNINIINTSLNNNNKNKDEDNVNNNNGNNSNNNNNINNNNDEDNDEDNDENNNNNNNNNNNNNNNNNNNNNNTSNNDIPDLSWTNYNSDSFNNNNNNNNIFNTFLSISSPISDQQNTSPQIQEIISPLPSPPTVQQSDVIQQTTTTSPSPLPSPQKQKQQQQRPLQKSSPPPTTITTSTTTTTQFNNNNLASSLGSTSDLFNKSLISSFLNGQGISSINNSNPFENSYKNQINSSTNSGTNTFSNTNTNINTTNSSNTNVGYDQYSFNYSNGSNSNINNSNNGLKSFLSNSNSSFSALKNCSYDAKDMSSFTITLSNSELNTMIAESLNRSSASNSIVKSSNTVHTTSGGNNSLCSDGYNQNIISATTNTNTTTTNSSSTTTTTTATTTTASTTNNNINNNNNNSTSTTNSTKDITFLVCDNPDSTKEKSNVSNTSSIISASNLNRHITPNSHMRPRGRSISESLIMSPINKESLNDIQRAIESEKIKKTKFEELKSILGEREYIIDINDIQFIQKVGEGAFSEVWEGWWKGIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACYKPACIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTMTNGGICNPRWRPPELTKNLGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIVNKLKEISWNNPIGFVSDQFYQYSEPSTPRLALSNQSSNSSSISLSPTKL
What are the official names of this protein?
Dual specificity protein kinase splB, Non-receptor tyrosine kinase spore lysis B, Tyrosine-protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Tyr protein kinase family.
Protein: Y1345_METJA
Sequence: MGEGVNMEIYNESILWDEYFDALEKRNYEKALLLIDKILEVRESPDVYVRKARILRTLGENDKALEYFDKALKLKPKYILANFLKGALLVSLGKLEEAKEVFLKLCRLEKSDLPVKYVTAFILKKLGEYDYALKIIDKILKKYPKSAIAWAEKGEILYREGKLKKSLECFDNALKINPKDCQSLLYKGEILFKLGRYGEALKCLKKVFERNNKDIRALMYIIQILIYLGRLNQALEYTKKALKLNPDDPLLYLYKGIILNKLGKYNEAIKYFDKVLEINPNIPDAWNGKAIALEKLGKINEAIECYNRALDIYE
What are the official names of this protein?
TPR repeat-containing protein MJ1345.
Protein: ATG18_ASHGO
Sequence: MSRTGMPVINFINFNQTGTCISMGTSEGLKIFNCDPFGRFYSDEDGGCGIVEMLFSTSLLAVVGIGDNPSMSPRRLRILNTKRHSVICEVTFPTTILAVKMNRSRLVVLLQEQIYIYDINSMRLLYTIETSSNPRGLISMSPSLENNYLAYPSPPKVINSGIKSNANTNNIGISARSSIAEGGSEYLDKGTEPLTDSSKAGADLNSVKASTETTISPGKEHSAGSGLNATSSSGTVKNGDVIFFNLQTLQPTMVIEAHKGEIAALALSKDGTLLATASEKGTIIRVFSVETCTKVYQFRRGTYPTRIYSLNFSDDNEFLAASSSNKTVHIFKLGKPNAENSSAAATNSDDDEGEADSDDGADDDGVGDSDDTRSTVSIESFDNGSHQTREPIVDSSRKTVGRMIRKSSQNLSRKAAKALGSYFPKKVTSILEPRRHFASLKIPIESGSNLKTICTIGEPLTLDISDYPELFSGSRTMAQSASISANSSDSSLTRNSNFVKMIPIRVVSSEGYMYNYVLDPERGGDCLLLSQYPLLMD
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct ATG9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: SDA1_SCHPO
Sequence: MVKRRTAAVLPNNLPHLQHLVKKDPKSYREEFLQQWNHYETAREIFLVNPSSDISEFCSLIDFISQTCNYYHDVTADFPSELIELLQKNHTIFPFELCEKIVLCLVLLKNKTVISPITLLQCFFPLFRENPTRGVRELLYQQVSLTIRNANKQAKNDKLNKAVQSALFTLVDGSGSGSATHTDYSGQKREYSASELSGVWAVKMVRDLWKRNVWSGDARAVNIMKSAALSSNPKVMLAGIYFFLGADNQEEEEESDDEGPDVSKLLHQANVNKKTKSREAALLRARAVVKKKERGKQNVPTNVNFPALQLLHDPQGFAEELFEKHLASSKSRLSMDQKLVVLRLLTRLVGSHKLTVLGLYSFLMKYLTPHQRDVTQFLACLAQASHEFVPPDALEPLVRKIADEFVTSGVANEVVCAGINAIREVCARAPLAMTPDLLQDLTEYKSSKDKGVMMASRSLITLYREVAPDMLKRKDRGKLASIEMKDRTPLKYGEELNVTHGIQGLELLAQYKAEHGEEGENGDDWDNWEVSEDGQNSDDSGGWIDVDSDDNIELSDSDEEEEKATARKESDEKGSSSQKELVDRMTELASQSILTPNDLKKLEELREQAGVDRLVNGPKRSLKRPDDAVEADEIEGPRKKAKNDREARIASVMEGREGRDKFSSKKAGFNPTSLSNKRKQRNKNFMMIKHKLKGKAGRSLVQKQKVLREHVAREKRKIK
What is the function of this protein?
Required for 60S pre-ribosomal subunits export to the cytoplasm.  May also be required for 60S ribosomal subunit maturation and accumulation (By similarity).
What are the official names of this protein?
Protein sda1.
What is the protein family that this protein belongs to?
Belongs to the SDA1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NFI_PARUW
Sequence: MSQRFNFDPSFLQPDSIEKATIIQKELANRICLEDEFNTPEFFGGMDVSNNLFDPKQIIYATAILLDSKMLSVQFHNSVSQRQTFPYIPGFLGFREAPALIDALESLPKLPDMIFVDGQGISHPRRLGIASHIGVLVNIPTIGVAKNILFGEPKKDLGSCVGDYVFLYAYGKEIGALVRTKLRCKPLIISTGHRVSLRTAIEYVLNCVKGYRLPEPTRQAHLAANAFRKQSQAGN
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_CHLAA
Sequence: MSRIAETFARLRAAGRIALMPYLTVGFPERTSTLELVPALEAAGASLFELGIPFSDPLADGTTIQRATQRALENGITIADCIATVAELRARRVAAPLLLMGYYNPLLRYGLERACAALAAAGGDGWIIPDLPLEEADDLRQLAAAHQLDLIMFIAPTTPPARISQITAQASGFLYIVSLTGVTGARQTLAGNLTDLIANVRQQTNLPLVVGFGISQPAHIAEVARIADGAIVGSALIDRLERLPPEDRVSGAAAYIRELLSAVARP
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CLPP_RICTY
Sequence: MSYIPVVIEQTSRGERAYDIYSRLLKERIIFVCSTVEDHMANLIVAQLLFLEAENPKKDIYMYINSPGGVVTAGLAIYDTMQFIKPKVATLCIGQACSMGSLLLCGGEHGMRYSLPHSRIMIHQPSGGYKGQATDIEIHARETLKIKKLLNELYSKHTEQALKHIEKSMERDNFMSPGEAKKFGLVDNIISSRDAMALLHK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_PSEE4
Sequence: MTEQQPVAVLGGGSFGTAVANLLAENGHPVRQWMRDPAQAESMRVNRENPRYLKGIRLHDGVQPVNDLLATLQGSELIFVALPSSALRSVLAPHAELLRGKGLVSLTKGIEAHTFKLMSQILEEIAPEARIGVLSGPNLAREIAEHALTATVVASEDEALCRQVQEVLHGRTFRVYASTDRFGVELGGALKNVYAIIAGMAVALGMGENTKSMLITRALAEMTRFAVSQGANPMTFLGLAGVGDLIVTCSSPKSRNYQVGHALGQGLTLEEAVSRLGEVAEGVNTLKVLKAKAQEVQVYMPLVAGLHAILFEGRTLNQVIEHLMRAEPKTDVDFISTSGFN
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.