PharMolix/UniProtQA huggingface dataset:
Protein: VNNL1_DROME
Sequence: MSNTWWWLSVVLLILGLMPGMSQQAALAESDYYTAGVVEFKQSILSLSAWSDSLAGYVEIINSENASATDIIVFPESTLNSAGSTTFVPNPEDQINPCLSDPNATYYEEFLVTLSCAARNASKYIVINLTEKQKCEDIPEDTRPCASNGLNVFNTNVVFDRQGVVVSRYRKVHLYGEAKNSTFLPELITFETDFGVTFGHFICFDILFYTPAHQLIVEQGITDFVYPAMWFSQLPFLTAVQTQQGWAYANDVNLLASGASRPSIGNSGSGIYHGRSGTLTSVMRQDSGERAIYVAQVPKYTRSRSLKKRAKRSLQEIQTRQVASSSSFYMKRDYVENYESELLKLDEGTSGAINRTICQGSFCCNFDIAWRSLGTATENGSYYSYRLGTYDGWRNENNVDANYIRNCALFTCSGDSIDDCGKLLPTEGELQQSRVTFTRLAIGVTYPESREFLLFPDTLQDSLLPLEPSQFEWSQRKPTEDSYVQEVRFALKETQELSNLLTFGIYGNYYDNECTFGVGTEEEQLACGYRSGSPGLRILGGWLAMPLIILAIARTMSS
What are the official names of this protein?
Vanin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: DAPA_BDEBA
Sequence: MKNFKGTFTALVTPFKNGKIDFASLDKLLKQQLAGGVDGFVVNGTTGESPVLTSSEKAELFKHIRNVCGDKVVLIMGTGSNNTAQTIEDSRKAEEMGADAILVVVPYYNKPPQRGLYEHFKAVASSVKIPTILYNVPGRTITSLETGTIRDLAKVKGVVGIKEATGKIDLASEIIKACGSEFVMLSGDDGTYVEFLGVGGHGVISVASHVIPAQMVQWKKWVSEGALDKARADIAKYNDLINLLFVEANPIPVKKALQLMGILESAELRLPLVELGAENTAKLQAEMKKVGVL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_LEGPA
Sequence: MATPLKLYRNIGIAAHVDAGKTTTTERVLYYTGMSHKIGEVHDGAATMDWMVQEQERGITITSAATTCYWSGMDKQFESHRINIIDTPGHVDFMIEVERSLRVLDGAVVVFDSVAGVEPQSETVWRQANKYGVPRIVFVNKMDRMGANFLRVVSQIKQRLGSTPVVLQLPIGAEEEFKGVIDLIKMKAIHWDEENKGMTFKYVDIPADLKATCEEYRAHIIEAAAEYSEELMEKYLEGEEFTEAEIKKALRHLTITNKVVPVFCGSAFKNKGVQAVLDGVIEYLPSPTDIPDIQGVDEHGDEIHRKTSYDEPFSALAFKIATDPFVGTLTYFRAYSGILKSGDTVYNSVKGKKERIGRLLQMHANSREEIKEVRAGDIAAAVGLKTVTTGDTLCDQDKVVILERMDFPDPVIAVAVEPKTKADQEKMGIALGKLAQEDPSFRVHTDEESGQTIIQGMGELHLEIIVDRMKREFNVEANVGKPQVAYRETLKQAVEQEGKFVRQSGGRGQYGHVWLKIEPQEPGKGYEFINAIVGGVIPKEYIPAVDKGIQEQMQNGVIAGYPVVDVKVTLFDGSFHEVDSSEMAFKIAGSQCFKQGALKAKPVLLEPIMSVEVVTPEDYMGDVMGDLNRRRGLVQGMEDSPAGKIVRAEVPLAEMFGYSTDLRSATQGRATYTMEFCKYAEAPTNIAEAIIKKQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM042_HUMAN
Sequence: MFRKIHSIFNSSPQRKTAAESPFYEGASPAVKLIRSSSMYVVGDHGEKFSESLKKYKSTSSMDTSLYYLRQEEDRAWMYSRTQDCLQYLQELLALRKKYLSSFSDLKPHRTQGISSTSSKSSKGGKKTPVRSTPKEIKKATPKKYSQFSADVAEAIAFFDSIIAELDTERRPRAAEASLPNEDVDFDVATSSREHSLHSNWILRAPRRHSEDIAAHTVHTVDGQFRRSTEHRTVGTQRRLERHPIYLPKAVEGAFNTWKFKPKACKKDLGSSRQILFNFSGEDMEWDAELFALEPQLSPGEDYYETENPKGQWLLRERLWERTVP
What are the official names of this protein?
Uncharacterized protein C13orf42.
Protein: QUEA_HELMI
Sequence: MEVALYDYELPKEAIAQTPVEPRDASRLMVLERRTGAVDHRIFRDLVHILHPGDLLVVNRTRVIPARLFGKKRDSDVTVEIVLLTPMGDDRWEVLVRPGRRLKPGVFVDLGEGRLAAEIVETTDFGGRVVRFHYSGDFDTLIDEIGQMPLPPYIETALPRQEAERYQTVYSQERGSAAAPTAGLHFTPQLLEDLKKRGIEITSVLLHVGLGTFRPVQVDRIEEHKMHSEFFQVDPEAARAIAKAKQEGRRVIAVGTTVARTLETAAGLHNGTVAAGSGWTDIFIYPGYTFQCIDGLITNFHLPRSTLLMLVSAFAGREQVLAAYREALEKGYRFFSFGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_PARP8
Sequence: MAKNKFNTSWLHDHINDPYVKMAQREGYRARAAYKLKEIDEQDKLIRPGQVIVDLGAAPGSWSQYVRNKLSQGKHRDAQREGGIDGTIIALDLLPMEPIADVHFIQGDFREDNVLAQLEEVVGDRDVDLVISDMAPNLSGVAVADAARIEHVCDLALEFAQNHLKPDGALLVKCFHGSGYSQIVEKFKHQFKTVAARKPKASRDKSSETFILGRHLKRPR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_CAUVN
Sequence: MSDAFKPLLAKLADGQTLDDSDAELFFAACLRGEPTPAQVAAAVTAIRLRGETVGEIAACARAMRRAAIPLEHPYDVIDVCGTGGDGLHTLNISTAVGFVAAGGGLKVAKHGNRAITSKSGTADVLTALGVNIDATREQQRKALDEAGICFLFAQAHHGAMKHVSPIRQQLGFRTIFNLLGPLTNPAGAKRQVVGVSAPRFVEPIAKALGALGAERAWSVHGSGMDELTTTGETEVAEWRDGVVRLFKITPEAVGLPRAALADLTGGDPAFNAAALTRLFDGETGPYRDIVLLNAAAAFLVADKVETLVEGVALAAEAIDSGRAKAALAGLVAATNTEVPA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: DPO4_SHIDS
Sequence: MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAIGLRTCGDVQKCDLVILLKRFGKFGRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCP_IRV9
Sequence: MSMSSSNITSGFIDIATFDEIEKYMYGGPTATAYFVREIRKSTWFTQVPVPLSRNTGNAAFGQEWSVSISRAGDYLLQTWLRVNIPQVTLNPLLAATFSLRWTRNLMHNLIREATITFNDLVAARFDNYHLDFWSAFTVPASKRTGYDNMIGNVSSLINPVAPGGNLGSTGGTNLNLPLPFFFSRDTGVALPTAALPYNEMQINFNFRDWTELLVLQNSALVAPASPYVPIVVPTHLTVAPVLGPVQVWANYAIVSNEERRRMGCAIRDILIEQVQTAPRQNYTPLTNASPTFDIRFSHAIKALFFSVRNKTSASEWSNYATSSPVVTGATVNFEPTGSFDPIANTTLIYENTNRLGAMGSDYFSLINPFYHAPTIPSFIGYHLYSYSLHFYDLDPMGSTNYGKLTNVSVVPQASPAAVNAASGAGGFPGSDYPQSYEFVIVAVNNNIVRISGGETPQNYLSGSFVTLLNRRKWSREGPMIMVQ
What is the function of this protein?
Major capsid protein that self assembles to form an icosahedral capsid.  Represents around 50% of the total virion protein mass (By similarity).
What are the official names of this protein?
Major capsid protein, MCP, P50.
What is the protein family that this protein belongs to?
Belongs to the NCLDV major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: AB5B_ARATH
Sequence: MKKGNLEANTKTVPFYKLFFFSDSTDVLLMIVGSIGAIANGVCSPLMTLLFGELIDAMGPNQNNEEIVERVSKVCLSLVYLGLGALGAAFLQVACWMITGERQAARIRSLYLKTILRQDIGFFDVEMTTGEVVGRMSGDTVLILDAMGEKVGKFIQLISTFVGGFVIAFLRGWLLTLVMLTSIPLLAMSGAAIAIIVTRASSQEQAAYAKASNVVEQTLGSIRTVASFTGEKQAMSSYKELINLAYKSNVKQGFVTGLGLGVMFLVFFSTYALGTWFGGEMILRKGYTGGAVINVMVTVVSSSIALGQASPCLTAFTAGKAAAYKMFETIEREPLIDTFDLNGKVLEDIRGEIELRDVCFSYPARPKEEVFGGFSLLIPSGTTTALVGESGSGKSTVISLIERFYDPNSGQVLIDGVDLKEFQLKWIRGKIGLVSQEPVLFSSSIMENIGYGKEGATVEEIQAASKLANAAKFIDKLPLGLETLVGEHGTQLSGGQKQRIAIARAILKDPRILLLDEATSALDAESERVVQEALDRIMVNRTTVIVAHRLSTVRNADIIAVIHRGKIVEEGSHSELLKDHEGAYSQLLRLQEINKESKRLEISDGSISSGSSRGNNSTRQDDDSFSVLGLLAGQDSTKMSQELSQKVSFTRIAALNKPEIPILILGTLVGAVNGTIFPIFGILFAKVIEAFFKAPHELKRDSRFWSMIFVLLGVAAVIVYPTTNYLFAIAGGRLIRRIRSMCFEKVVHMEVGWFDEPGNSSGAMGARLSADAALIRTLVGDSLCLSVKNVASLVTGLIIAFTASWEVAIIILVIIPFIGINGYIQIKFMKGFSADAKAKYEEASQVANDAVGSIRTVASFCAEEKVMEMYKKRCEDTIKSGIKQGLISGVGFGISFFVLYSVYASCFYVGARLVKAGRTNFNDVFQVFLALTLTAVGISQASSFAPDSSKGKGAAVSIFRIIDRISKIDSRDESGMVLENVKGDIELCHISFTYQTRPDVQVFRDLCLSIRAGQTVALVGESGSGKSTVISLLQRFYDPDSGHITLDGVELKKLRLKWLRQQMGLVGQEPVLFNDTIRANIAYGKGGEEATEAEIIAASELANAHRFISSIQKGYDTVVGERGIQLSGGQKQRVAIARAIVKEPKILLLDEATSALDAESERVVQDALDRVMVNRTTIVVAHRLSTIKNADVIAVVKNGVIAEKGTHETLINIEGGVYASLVQLHINASN
What are the official names of this protein?
ABC transporter B family member 5, ABC transporter ABCB.5, AtABCB5, P-glycoprotein 5, Putative multidrug resistance protein 5.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SIAT2_DANRE
Sequence: MKSSLKQWRRLALGLILVWALLFLALLSYFMESRVDDPHAAAALSYTDTRRLTSLQGNPRTIMATHLGLATSSAPSTSSNTQQEQSQEENPSADPQPSPLSQEAYPYPDPQSLAAWSAFGTQDVGSRSTGVSRNRERQEYNQDSPQEDEDEEEEVIGGEEEDEEGGDEGRGRTTKRVARHGSSDPHEYYVPRYKSIVHGLWKGSLSMGMLSPRLQRAMKDYLNNNKHGVAYRGHRKAKQSRQQVLCELKKREKIRTLDGAEMPFSKLGWQKIVPALPLSQIHRPGLKTCAVVTSAGAMLHSGLGKEIDSHDAVLRFNTAPTVGYERDVGNKTTIRIINSQILANPMHRFNRSSLYKNVTLVAWDPAPYTLNLHQWYSNPDYNLFTPYMEYRMRFPSQPFYILHPKYIWQLWDVIQANNLENIQPNPPSSGFIGILLMMSLCEEVHVYEYIPSLRQTDLCHYHERYYDAACTLGAYHPLLYEKMLIQRMNIGSEDELKRKGKVTLPGFNKVHCEP
What is the function of this protein?
Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.
What are the official names of this protein?
Beta-galactoside alpha-2,6-sialyltransferase 2, Alpha 2,6-ST 2, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2, ST6Gal II, ST6GalII, Sialyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: GPA11_CAEEL
Sequence: MSAADMARKNSLINRQLEKEKIDSKKMLKILLLGGPECGKSTIFKQMKIIHMNGFSDLDYVNFRYLIYSNIMQSMDQLLEAAEFFHFPPDDSPSIRRALNHYKSYKVRYSTSEVELNRELADSLSKLYNAEFIKSVLNRKNELKLLDSAVYFLDDIDRISAHEYKPTEMDVLRARVPTTGITEIEFPFKQASLRMVDVGGQRSEQRKWIHCFDNVNGVLFIAAISGYNLYDEDEENRKDDGTPTKTNRLRYSMELFKRIANHQCFSKKTAMILFLNKIDIFKEKIGKYPLTTCFKNYKGVNAFEPACKYVTDRFSRLVSGDIQHEKPLYTHITNATDTRNIDRVFDSCMDVIFKISMEKVGFM
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  Mediates the transduction of food and serotonin signals, which modulates the avoidance response to the odorant octanol.  Has a role in lifespan to promote longevity.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-11 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: SELT2_DANRE
Sequence: MAEYSQTGILTALLLFTVVTVKDIYVGRNSVTQQENTGPDINTQRQNKHTFYTGPVLKFQYCISUGYSKVFQEYSRSISQLYPDIRIEGDNYPPKPINKYLGNFLSYFKLLAIALIVTGQNPFQMFGMNTPRIWAWGQENKIFSCLMAFFISNMLETHFLSTGAFEITLNDIPIWSKLQSGYVPNIQELFQILDNHLKMNQADKMNFPSP
What are the official names of this protein?
Selenoprotein T2.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family. Selenoprotein T subfamily.
Protein: INS1B_DANRE
Sequence: MPKGFLVKRNKKAALVSYRIRTDEDGGPTPECPIAQIALSSPAPSASKPDSILLAFPSAGAEAPVPVHKPVQFGNPEAVYQALYSPTRPVSKDHDRKYFERSLNLGSPISAESFPTPASLTSLDHHLLFAPVDLKIGTSNSNRSGTASGAHAPAIQTGAKRPSADAAERKVSSKSAKKPKAIRKLNFEDEVTTSPVLGLKIKEGPVDLKPRPSSGGTNKPLGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECEKVFSCPANLASHRRWHKPRVQSAPKQALQPAKPFPEELRAEFPSDRDTPSPGLSESGSEDGLYDCQHCGKRFKRQAYLRKHILGHQALQNQILGEAFRSAESPDAMPSEDRQSPAPLNLSPADCLTCPACGEKLPNRASLERHLRLLHDDAQAFPCKFCPATFYSSPGLTRHINKCHPTENRQVILLQMPVRNAC
What is the function of this protein?
May act as a transcriptional regulator.  May play a role in neurogenesis and neuroendocrine cell differentiation during embryonic development (By similarity).
What are the official names of this protein?
Insulinoma-associated protein 1b, Insulinoma-associated 1-like protein b, Zinc finger protein IA-1b.
What is the protein family that this protein belongs to?
Belongs to the INSM1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVA_XANC5
Sequence: MIGRLRGILAYKQPPWLVIDVGGVGYELEAPMSTFYDLPDVGRDVILFTHYAQKEDSVALYGFLREGERRLFRDVQKVTGIGAKIALAVLSGVSVDEFARLITSGDITALTRIPGIGKKTAERMVVELRDRAADFSSGAPITGQLGPDAVSEATVALQQLGYKPAEAARMARDAGAEGDEVATVIRKALQAALR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: NHAA_MARMM
Sequence: MTKNSTECSPANQTGLERVLRSPAIAGLVLLVSMLVAFFWVNSPFADSYEAIHHAPAAISIGSFELAKPLILWINEGLMIVFFFLIGLEIKREVFEGQLSSPKQIALPAFAALGGMLVPAAIFLAFNNGSEEYVRGWAVPAATDIVLALALLAMLGSRVPIALKVFLTALAIFDDFGTLVIIALAYSEGLSLPSLLMAALGTLALIVLNRLRVASLTAYVLVGVFVWVSVLESGVHSTLAGVIIAWCIPMRVSGREFLHKIEHDLSPWVALLIVPLFAFFNAGIDLGGVDFETFFGPLGLGIILGLFVGKQVGVMLGVGLAVVLRIGARPIEVSWGHLYGAALLSGVGFTMSLFVAGLAFEQPGAVLTVNLAVVVGSVLSATGGLVVLARSYQTSPSLANAPD
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLA2_SCHPO
Sequence: MKYLAAYLLLTVGGKDSPSASDIESVLSTVGIEAESERIETLINELNGKDIDELIAAGNEKLATVPTGGAASAAPAAAAGGAAPAAEEAAKEEAKEEEESDEDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2-alpha, A2, L12EI, L40C.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: VIN3_ARATH
Sequence: MQAASLSKIWRFDGNVGPENMDSSSFEDNECIETCKPNVLNVSERRELIHALSNQPEEASELLNSWSRNEIMKIICAEMGKERKYTGLNKPKLIENLLNLVSRPLGETSCSDRRNSRKKEKKMIGYIICCENLACRAALGCDDTFCRRCSCCICQKFDDNKDPSLWLTCDACGSSCHLECGLKQDRYGIGSDDLDGRFYCAYCGKDNDLLGCWRKQVKVAKETRRVDVLCYRLSLGQKLLRGTTKYRNLLELMDEAVKKLEGDVGPLSGWAMKMARGIVNRLSSGVHVQKLCSQAMEALDKVVSPSESVSGQGDKMTVRVEEIQARSVTVRVDSEEPSSSTQNKITGFRLFCRKSKDEECSSQGNCVVYLPETTSAIQGLEPDTEFCLRVVSFNEEGDLDESELRFTTLKDDGDEAGDQQSPLTNSSSGLCSNPSLPEDESNNVNKSCSKGNGDKDNTEHCSAGEVESELEEERLVKRKANKIDGRDLLVTPCKRDIYKGKQGGNKRFKSRTVSLNEKPEINNAANGVGDKDLGHIVKTIRCLEEEGHIDKSFRERFLTWYSLRATHREVRVVKIFVETFMEDLSSLGQQLVDTFSESILSKRSSTNGVVPAGICLKLWH
What is the function of this protein?
Plays a central role in vernalization by mediating the initial transcriptional repression of the homeotic gene FLC, a floral repressor, after a cold treatment.  However, due to its transient expression, it cannot maintain repression of FLC, which is then maintained by Polycomb Group complexes containing VRN2 throughout development.  Required to deacetylate histones on the FLC promoter.  Together with VIL1, required during vernalization for the modifications of FLC and FLM chromatin that are associated with an epigenetically silenced state (e. g.  chromatin modifications, histone deacetylation, and trimethylated H3 'Lys-4' H3K4me3 and 'Lys-27' H3K27me3) and with acquisition of competence to flower.
What are the official names of this protein?
Protein VERNALIZATION INSENSITIVE 3.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Probably DNA- associated; interacts directly with the FLC regulatory regions.
Protein: MCH_METPE
Sequence: MLSVNELALEIFENLAEFAEEFNAAYHELGNGARIVDCGVSTRGGYSAGRAFTEICMGGLGEVNFRMGEISGIPMPFIDVNTDFPSISCLGAQKAGWTVKVGNYFAMGSGPARALALKPKHTYEVIGYEDDFDSAVIALESDHLPNGEVMEKIAAECHVDVGNVCAVVAPTASPVGSIQVSGRCVETAIYKLNELGFDTTKIISAIGSAPIPPVKKDATRAMGCTNDATIYHGRILLTMKAPEIKDYLDKIPSNKSKGYGKPFYDIFKEAEFDFYKIDTSLFSPAEVIINELTEGVVYHVGAVNPEVTLKSFGLL
What is the function of this protein?
Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
What are the official names of this protein?
Methenyltetrahydromethanopterin cyclohydrolase, Methenyl-H4MPT cyclohydrolase.
What is the protein family that this protein belongs to?
Belongs to the MCH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_RICCN
Sequence: MLNIGLSGSTGKMGETILERIDKFKDCKIAAKFNSTNNLDDLDNFCKNSDVIIDFSTPEILEKLINYALKHNTKLVIGTTGLQPQHFKLLEKAAQTLPVLYSANMSIGANLLSYLAKEVTKILDDYDVEILETHHRNKKDSPSGTAVMLAETIASKKGLNITFNRGNRLRSEKEIGISSLRGGNVHGIHEISFLGDDEIITLKHEALNKNSFSIGAIKAAIWLQDKPSALYSMQDIYKI
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_LACP3
Sequence: MNNGMQIFDYEDIQMIPNKCVVQSRKEVDTSVKFGPHTFKIPVVPANMQTIIDEPLAIWLAEHDYFYIMHRFQPERRMDFVRDMKKRGLIASISVGVKDDEFDFIEALAANELTPDYITIDIAHGYAQVVIDMIQHIKHYLPNAFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKLKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRNNGDIAKSIRFGATMCMIGSLFAGHEETPGKHVNIDGKEYQEYYGSASEYQKGTHHNVEGKKILLPVKGKIGDTLKEMQEDLQSAVSYAGGRDLESLTKVDYVIVKNSIFNGDQY
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: GREA_STAA8
Sequence: MENQKQYPMTQEGFEKLERELEELKTVKRPEVVEKIKVARSFGDLSENSEYDAAKDEQGFIEQDIQRIEHMLRNALIIEDTGDNNVVKIGKTVTFVELPGDEEESYQIVGSAESDAFNGKISNESPMAKALIGKGLDDEVRVPLPNGGEMNVKIVNIQ
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: Y1682_STRPD
Sequence: MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGKQSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNLHAGGSAQMAAFQLMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAHVTALASRPKLIGGARADYNMDIIRKS
What are the official names of this protein?
UPF0340 protein MGAS10270_Spy1682.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: PROA_SHIF8
Sequence: MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALTQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR358_MIMIV
Sequence: MNIFIRKHMIPYLSEYTQMFIVLFGAKVVVCDDTYNFQQFLEHKNNLNLFYKTFPPHIENAIPQILQHNIKIYLVNIDQLGWRNLNTVKKALSNKIKVIDYSSENISLTKDINHVHIPLLLYNDIIIRDNLEIKYDIGFSGGDFPRRSTILKQLSNKYNVININKFGKKRDILTKQCRIVLNIHAFDSLSTTETLRCYPLIYNKILTVSENTPLIESSTYGTEINKFIVFVDYDKIVSKCEEILSNYDQYYNSVFKDFDETKIKHMVDNHIETINQNIFN
What are the official names of this protein?
Uncharacterized protein R358.
Protein: PNP_AYWBP
Sequence: MLKKVFETTNLKDSFQVEIGTYARNVDSSILVRYQDTVVLTTMVFSRKPNNLDFLPLTVIYQEKLYAAGKIPGSFLRREGRSNDHEILTSRLIDRSLRPLFPDYFQQEVQVINTVLSLDPDFKSELASMLGSSLSLLISEIPFFEAISGVYVGKINNEFIINPTLQQLANSTLHLIVAGTKHNVTMIEAHANEVSEQDFLEAINFAHQYIKKLCLFQENIKQQFAPVKMTKTLHQTEQIQQQSFFAKNHSQVKQAILSCNSKNDLQQLKEQILDQAKQTPFFKTIDAITVFDYEAHKKHLQITENLFQKLSKQEMRSLILQEKIRPDKRELEEIRTLESQIDLLPRAHGSALFTRGKTQSLAAVTLGCLSESKIIDGLSDEQNKRFMLHYNFPPFSVGAVGRYTAPSRREIGHGTLAEKAISQVLPEEKDFPYTIRVVSEILESNGSSSQATVCSSSLALMASGVPLKKAVAGISVGLVFDQETNKYVILSDIQGLEDHVGDMDLKIAGTNKGITALQMDLKIQGIPFKILQEAFLQAKKGRLHILEQMNQTISQPRLEVSKYAPKVCMMQIKPEKIRDIIGSGGKIINQIIESHDGVKIDIEQDGRVFVMHSNLETVKKTVAFIESLIQEIQVGTCYQASILRFLSDKQGKMIGAVAQVCPGIEGLIHVNKMKFQKITDVLKIGETVLVKCTKINERGRIDFLLLPKKTQEKNS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBS1L_HUMAN
Sequence: MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYEDLKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE
What is the function of this protein?
Facilitates the association of the exosome complex with the SKI complex.
What are the official names of this protein?
HBS1-like protein, ERFS.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family.