PharMolix/UniProtQA huggingface dataset:
Protein: DAPE_BARQU
Sequence: MPVLTDPLQLLQALIRCPSVTPYEAGALSTLEQILTKMGFNVKRPVFTDKNTEDVENLYAKMGGEGRHLMFAGHTDVVPPGALEDWTYPPFEGVIDQGKLYGRGAVDMKGGIACFVAALARILEKRSIKGMVSLLITGDEEGPALNGTVKLLKWAEQKGEKWTAALVGEPTSVKTVGDVIKIGRRGSLSGVVTVKGRQGHVAFPERAANPLPLAGKLIQALTQTALDRGTENFQPSNLELTTIDTDNPAVNVIPAQTTIRFNIRYNDVWTKETLMTEIEKRLASVQLKNNDYQYPYYQLEWIPSLGSVFITKNDKLIKTLSNAIESVTGNIPEYSTSGGTSDARFIKDYCPVVEFGLPGQTMHMVDECVTLDAIETLTSVYERFIVDFFA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RPOE_LACAC
Sequence: MGLDKFKDKNRDELSMIEVARAILEDNGKRMAFADIVNAVQKYLNKSDEEIRERLPQFYTDMNTDGEFISMGENVWALRSWFPYESVDEEVNHPEDEEEDDSRKHHKKVNAFLASATGDDDIIDYDNDDPEDDDLDAATDDSDDDYSDDDSDYDEDNDDADDVLPDGIEGQLSQLNDEDDDEDD
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: MDTK_KLEP7
Sequence: MQKYFVEARQLLALAIPVILAQVAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVVAQLNGSGRRERIAPQVRQGFWLAGFVSVLIMVVLWNAGYIISSMHNIDPLLAEKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATASVYWVMFASMLWWVRRARTMRDIRCAERFSGPDFAVLLRLVQLGLPIALALFFEVTLFAVVALLVSPLGIIDVAGHQIALNFSSLMFVLPLSLAAAVTIRVGFRLGQGSTIDAQVSARTGVGVGVCLAVFTAIFTVLMRKQIALLYNDNPEVVTLASHLMLLAAIYQISDSIQVIGSGILRGYKDTRSIFFITFTAYWVLGLPSGYLLALTDMIVPRMGPAGFWCGFIIGLTSAAIMMMLRMRFLQRQPSSIILQRAAR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MIAA_PROMM
Sequence: MPASKPLLIALLGPTASGKTCLALQLAEQLKLSVLNVDSRQLYIGMDVGTAKPTKEQQRRVQHHLIDLRRPDQPITLQEFQAAAQLILAQKLREQNMPFLVGGSGLYLKALTCGLRPPAVPPQPELRKQLGELGQRTCHHLLQAADPTAANRISPADAMRTQRGLEVVYATGKPITTQQGSSPPPWRVLELGLDPHNLRERIGHRTTQLYANGLIEETEHLSHCYDTDLPLLQTIGYGEALKVIQGLLNREQAIALTTRRTQQFAKRQRTWFRRQHHPYWLKGEEPLSEALSLIQAGLR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: UVRB_CHLL2
Sequence: MYGITGNGYRLVSSYSPKGDQPKAIEQLVEGVQRGDRWQTLLGVTGSGKTFTISNLIAQVGKPVLVMSHNKTLAAQLYGELRQFFPDNAVEYFISYYDFYQPEAYLPALDKYIAKDLRINDEIERLRLKATSSLLSGRRDVIVVSSVSCIYGLGSPEEWKAQIIELRPGMEKDRDQFLQELVSLHYVRDDMKPGPGKFRVRGDIIDLVPAHEELAVRVEFFGPEIESLQTFDMQSGEVLGRDDYAFIYPARQFVAGEEQMRHAMLAIENELAGRLNELRGENRLIEARRLEERTRYDLEMMKELGYCSGIENYSRHLAGREPGDRPHCLLDYFPEDYLVVVDESHVTLPQIRGMYGGDRSRKTILVEHGFRLPSALDNRPLRFDEYVGLVPQVVCVSATPGDLELEYSGGVIVEQLVRPTGLLDPPVEVRPVKGQIDDLLGEIRKHTARGFKALIMTLTKRMSEDLDDYFRKTGIRSRYLHSEIKSLERMQILRELRTGEIDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRNTRSLMQIAGRAARNSEGFVVLYADVLTRSIREVLDETSRRRKIQQAYNEEHGIVPQSIIKSVEQVLNTTGVADAEERYRRKRFGLEPKPERLLSTLIDTLTAEECYSMAESLRLEMQEAALKMEYEKAAYLRDEITKFEHRANEAGKGI
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P4KG1_ARATH
Sequence: MNCLATTIIITCKPTLISDMAVAIDPFSDKFPYFNRSSQRCRLQSLTNLDFNFLAQSFNHTFEDDNIHRSVSSPCFSIAASANMEEDLKATTAPRIEILGGQRVPTVRALVAEVTMAMVSGAQPLLLPSGMGGAYLLQTGKGHNIAVAKPVDEEPLAFNNPKKSGNLMLGQPGMKHSIPVGETGIRELAAYLLDYQGFSGVPPTALVSISHVPFHVSDAFSFSSMPYKVASLQRFVGHDFDAGELGPGSFTATSVHRIGILDVRLLNLDRHAGNMLVKRCDKKEAYNRLGTAELVPIDHGLCLPECLDDPYFEWLNWPQALVPFSDTELDYISNLDPFKDAELLRTELHSLPESAIRVLVVCTVFLKQAAAAGLCLAEIGEKMTRDFSKGEESFSLLETLCTKAKASVFGKTSEDSDYSHEGNEVNTELQCGMFKFDGGDTPCEAEISEVFHVSKPPLVPRGPRANTIPNDVTASMSSSQNQRITHQEKSAKEKKRGGKQERCTVRSKSPPISPNHDESKGVSFVDMTTVEWDTFLQSFQTLLQDALSKGSTPRLGCSCEI
What is the function of this protein?
The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).
What are the official names of this protein?
Phosphatidylinositol 4-kinase gamma 1, AtPI4Kgamma1, PI-4Kgamma1, PI4K gamma 1.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
Protein: UBE2N_DICDI
Sequence: MATLPKRIIKETQRLMTEPAPGISATPATDNFRYFKVAISGPLDSPFEGGVFNLELFLTDDYPMSAPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEHWKTNEKEAMARAREWTRLYAEAPVEN
What is the function of this protein?
The ube2v/ube2n heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.  This type of poly-ubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  Plays a role in the control of progress through the cell cycle and differentiation.  Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
What are the official names of this protein?
Probable ubiquitin-conjugating enzyme E2 N, E2 ubiquitin-conjugating enzyme N, Ubiquitin carrier protein N, Ubiquitin-protein ligase N.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: THIG_PROMP
Sequence: MKEDSCLQIGGKSFSSRLMVGTGKYTSSEVMLESLANTESEIVTVAVRRIQNNQNGENLLEKIDWKKFWMLPNTAGCTNSDEAIRIAILGRELAKLSGQEENNFVKLEVIPDKKYLLPDPIETLKAAEILINKDFIVLPYINADPILAKKLEEIGCSTVMPLGSPIGSGQGLLNLSNISIIIENSNIPVIIDAGIGVPSEASQAMELGADGVLINSAIALAKNPLKMAKAMNYGVKAGREAFLAGRIEKQKLANASSPEINISIK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_RICAE
Sequence: MNNFSIISEYKPAGDQPKAIDEIIAGLSSKKRSQMLLGITGSGKTFTMANIIERTNRPTLIMAHNKTLAAQIYSEMKSLFPKNAVEYFVSYYDYYQPEAYIARTDTFIEKDSSINEQIDLMRHAATRSLLERRDVIVVSSVSCIYGLGSPDLYYQMMVNLEPGQSYPRDQLLNDLINLQYERNDIGFERGCFRVKGDNIDIFPSHYSDKAWRLSFFGNELEYIHEFDPLTGEKLAKLDKAMVFGNSHFVMPQETVNNAISGIEEELQKRLEFLKSQDKPLETQRLNQRTQYDLEMLTETGSCKGVENYSRFFTGRNAGEPPPTLFEYLPEDALLFVDESHVSVPQIRAMYNGDRARKKVLVEHGFRLPSALDNRPLKFEEWDKFRPQTVFVSATPGPFELEETGGTVVELIIRPTGLLDPECIIKPATNQVEDLISEMQTTIAQGFRVLVTTLTQKMAEDLTAYLQELKYKTSYLHSNVHTLERIEILRDLRQGTIDVLVGINLLREGLDIPECGLVAILDADKEGFLRSEVSLIQTIGRAARNSAGRVILYADKMTKSIDKAVSETLRRRQIQQEYNEKHGITPKTINRAIHALAEFEKIDSKLDKKQAHTLFDNAAKLKTHIDKLKKEMLKAASNLEFEQAVKLRDQLKTLEEAALELS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y898_CLOD6
Sequence: MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKRVLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRGYELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGANEYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPLNIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQSPTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEELNLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVVLNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPTAQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS
What are the official names of this protein?
UPF0371 protein CD630_08980.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: RS13_STRP1
Sequence: MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIRVKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNTKNNARTRKGKAVAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: EFP_PSEP1
Sequence: MKTGKELKPGTVLRIDNDPWLVQKAEFTKSGRNSAIMKTKLKNLLTGYKTETVYGADDKLDDVILDRKEATLSFINGDEYTFMDTTDYTMYELNAEDIEAVLPYIEEGMEDVCEAVFFEGRLVSVELPTTISRKVVYTENAARGDTSGKVMKPAKLANGTEISVADFIQIDEWIDIDTRDNSFKGRSKK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR33_PANPA
Sequence: MDLINSTDYLINASTLVRNSTQFLAPASKMIIALSLYISSIIGTITNGLYLWVLRFKMKQTVNTLLFFHLILSYFISTMILPFMATSQLQDNHWNFGTALCKVFNGTLSLGMFTSVFFLSAIGLDRYLLTLHPVWSQQHRTPRWASSIVLGVWISAAALSIPYLIFRQTHHDRKGKVTCQNNYAVSTNWESKEMQALRQWIHVACFISRFLLGFLLPFFIIIFCYERVASKVKERSLFKSSKPFKVMMTAIISFFVCWMPYHIHQGLLLTMNQSLLLELTLILTVLTTSFNTIFSPTLYLFVGENFKKVFKKSILALFESTFSEDSSVERTQT
What is the function of this protein?
Orphan receptor; could be a chemoattractant receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 33.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FGF2_MONDO
Sequence: MAAGSITTLPALSGDGGGGGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGIREKSDPNIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLALKYVTEECFFFERLESNNYNTYRSRKYSNWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
What is the function of this protein?
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).  Also acts as an integrin ligand which is required for FGF2 signaling (By similarity).  Binds to integrin ITGAV:ITGB3 (By similarity).  Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity).  Functions as a potent mitogen in vitro.  Can induce angiogenesis (By similarity).  Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism (By similarity). Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol (By similarity). Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity).
Protein: MUTL_KORVE
Sequence: MGRIHVLSEHVANKIAAGEVVERPASVVKELIENSLDAGAKRIRVHVEAGGKKLIHIVDDGIGMFRDDAMLAFERHATSKLKNPEDLLSISTLGFRGEALPSIASVARVRLETRANEEPSGTVLEIAGGKILKIEEAGLPLGTSIAIKDLFFNTPARKKFLKSESTELSHIASLVTHYALAHPEMHWELHSATNALLIAPPVATQSERIYQVFGNETLDQLIPLAAQIKLERIGLPKPPPWLRKNEDDEEEQTVEPGEVRLHGFISKPEIQKLNRNSIFVFVNGRLIRDRLVQHALTEAYRNILPPTLFPVVLLFLEMPYTEVDVNVHPSKTEVRFRQQSLVHDFVRDSVRAALSKARPIPQFISEIHAQPKASPSLTPGAQTAPAFALEAQEEPVLPERLQFGGDAISVEANAAVPVARFGAQTFGSHVAQQQTVPETSGCDYELPDLPAADAPLASLRPLGQIRESFILATSNEGLWIIDQHVAHERVLFEKVLKQRAAASVETQQLLMPLIVELTPGQQAVFTEIAEELHQNGFEVEPFGSRTFAVKAAPAGIRAEDIEKTLSEVLDSFEREQQAFNLEHAQSRIAATIACHAAIKVNMPLTQDKMEWLLAELAKTEHPMTCPHGRPIVLRYSVKDIQKAFKRI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RL1_LIMRJ
Sequence: MAKKRGKKYQDALKKVDSKKEYAVKDAVQLVKDIAYANFDSTIEVAFNLNVDTKQADQQLRGAVVLPNGTGKDQTVIVFANGENAKAAQEAGADFVGDDDLVEKIQDGWLDFDVAIATPDMMPKVGRLGRVLGPKGLMPNPKTGTVTMDVAKAVSDAKAGQVTYRTDRDGNVAVPFGKVSFDTDKLVENLATLEDIVAKARPASVRGTYIKHASISSTFGPSVTLDLTTF
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: K1C19_PONAB
Sequence: MTSYSYRQSSAMSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGGYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYSNLSASKVL
What is the function of this protein?
Involved in the organization of myofibers.  Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity).
What are the official names of this protein?
Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: SRFA_DICDI
Sequence: MSLSTVSNHIINPLGNVVYGNPSSPTSTSSSSSLTPTSTNEEMIKKEDSGTSEPSSPSTGECNGKKAGRRKIKIEFIDDKSRRHITFSKRKAGIMKKAYELSTLTGTQVLLLVASETGHVYTFATAKLQPLITRPEGKNLIQSCLNTPDNPNSPSMANQNSNNNSNLLQQQQQQQLQQQQQLQQQQQQQQQQQQQQQQQQQQQQAAQQAVQQQQQQQAAQQQAAQQQQLQLQQQQQQQQQQQQQQQQQQQQQQLQQLQQQQLLQQQQHQQIQQHQQQQQYINSNGYPETIYDIQDKDIERRLGKDNNNNNNNNNNNINNNNNNNNSNNNSGNNNSNNNNNNNNKNNSNNNSQYIQQQNLNIDLNYSNPNVYPIGNYFQQTVQSRYIQSSSSASSSPASPNQFNYSNHSMPLNNQFPPC
What is the function of this protein?
Required for proper slug migration, spore differentiation and stalk differentiation (under nonbuffered conditions).  Could be involved in late events of spore maturation necessary for spore stability.
What are the official names of this protein?
Serum response factor homolog A, DsSRF.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABP1_MANSE
Sequence: MAYLGKVYKFDREENFDGFLKSIGLSEEQVQKYLQYKPSSQLVKEGDKYKYISVSSDGTKETVFESGVETDDVVQGGLPIKTTYTVDGNTVTQVVNSAQGSATFKREYNGDELKVTITSSEWDGVAYRYYKA
What is the function of this protein?
Binds fatty acids in a 1:1 molar ratio.
What are the official names of this protein?
Fatty acid-binding protein 1, FABP 1.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JZT18_CHIGU
Sequence: MKTTILVVILGLTLLFALSAATELKDEERDCKGFQVKCKKDSECCSSYVCGRQWKWCVYPSPFGR
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Cg1b, U11-TRTX-Cg1b, Jingzhaotoxin-18, JZTX-18.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 32 (Jztx-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYP_ACIAC
Sequence: MKASQFFVSTLKEAPADAEVVSHKLMTRAGLIKKLGAGIYNYMPMGLRVIRKVEAIVREEMNRAGAVEVTMPVVQPAEYWQETGRFDKMGPELLRIRDRHGRDFVVQPTSEEVVTDIARQELRSYKQLPKNLYQIQTKFRDERRPRFGLMRGREFIMKDAYSFDRDQAAAKASYQVMAQAYRRIFDRFGLTYRAVAADSGAIGGDLSEEFQVIAATGEDAIVYCPQSDYAANMEKAEALPPQGPRPAASQALARTATPGKSTCADVAQLLGVPLQATVKSLVLATDETNESGEIVRSQVWLLLLRGDHDMNEIKVGKVPGLDAGFRFATVGEIEDHFGCRPGYLGPLNLRQPVRLVVDREVAVMADWICGANEVDFHMTGVNWGRDLPEPDVVADLRNVVAGDPSPDGKGTLAIERGIEVGHVFYLGTKYSRAMNATFLGEDGKPAFFEMGCYGIGITRLPAAAIEQNHDERGIIWPDAIAPFTVVVCPIGMDRSDEVRAAAEKLHADLLTAGVDVILDDRGERPGAMFADWELIGVPHRVVLSDRGLKEGQVEYQHRRDAAATKVASADIFAFIKDRIKV
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR11_NYMAL
Sequence: MTKPIPKIGSRRNSRISSRKSGCRTPIGVIHVQASFNNTIVTVTDPQGRVVSWSSAGTCGFKGTRRGTPFAAQTAAGNAIRAVVDQGMQRAEVMIKGPGLGRDAALRAIRRSGILLNFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: S39A4_BOVIN
Sequence: MALLGRPGLGPLLAVLAALAASGTTTRPVHLLTLLSSGQGALDRVALGGLLNTLAARVHCADGPCGKCLSVDDALALGRPEQPGAPSGQVLEPRHIARLSAAAALYLSDPAGTCAEVRAGRWAARADQLLVLLESSQALSVALTRLLQQIQARAAGQPTSQQACVDLPQLLGEAAGIGAPGSPGPVLAALLGHVWSGACFHALPTPQYFVDFVFRQHSSENPNITLDELAALMERLGLGGATEPHDSHSDDSPLGKGQGPVPLAAPNSSASAWDTLCLSAQDIMAVYGMSEQAGVTPDDWARLSPALLQQQLSGACSPQPTLPTQDQLSQAERYLYGSLATLLICLCSLLGLLLLSCASCSTTSHYIIQAFLSMAVGALTGDALLHLMPKVLGLHTHDGEDHGFQPTWHLLAVLGGLYAFFLFERLFNLLLPLDPEDPKDGACSHGHSHGGHSHGVSLQLAPSDFRQPKQLHEGSRADLVAEESPELLSPEPRRRSPGLRLLPYVITLGDAVHNFADGLAVGAAFLSSWKTGLATSLAVFCHEVPHELGDFAALLHAGLSVRRALLLNVASALTAFIGLYVALAAGVGEDGETWILAVAAGLFLYVALCDMLPAMLNVRDRRPWLLFLLHNVGLLGGWTVLLLLSLYEDNIAF
What is the function of this protein?
Plays an important role in cellular zinc homeostasis as a zinc transporter.  Regulated in response to zinc availability (By similarity).
What are the official names of this protein?
Zinc transporter ZIP4, Solute carrier family 39 member 4, Zrt- and Irt-like protein 4, ZIP-4.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note=Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability (By similarity).
Protein: CRFR1_HUMAN
Sequence: MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
What is the function of this protein?
G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin).  Has high affinity for CRH and UCN.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase.  Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.  Inhibits the activity of the calcium channel CACNA1H.  Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress.  Plays a role in the response to anxiogenic stimuli.
What are the official names of this protein?
Corticotropin-releasing factor receptor 1, CRF-R-1, CRF-R1, CRFR-1, Corticotropin-releasing hormone receptor 1, CRH-R-1, CRH-R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome. Note=Agonist-binding promotes endocytosis.