PharMolix/UniProtQA huggingface dataset:
Protein: OBLB_ASPCL
Sequence: MEASLHFPIDASLRAAVAVISAGAFYLLNLVIYRLFLSPLAKFPGPKLAAVTSWYELYYDLVHKGKYLFEIEKMHDKYGPIVRINPFELSIRDSEYYDELYVAGSVRPTDRYEAFVEGIVDFKGSHIATIEHDLHRKRRKPLDPYFSRLGVSRLEPMLGELTEKLIVNRFESFKRTGKVVRLDHAFTAYSGDVINRLCMDDPPDVLVDDPEFSPWWYNMFHNGIATLPLFMGLPWLIHVVRLIPVSILAKLDPGTQTFNKFKMMCDDHLRVAKREKAAQGSKDTSMMDARPTIFRHLLNSDLPPSELTDDLLSKEAQVLIGTGTITTAGSLCFICYHIVVNPAIKKRLQEDLKLIMANYPAKKPTWAELETATYLQAVIKEGLRLSFGTMHRRTRVSPKQPLQFRQWTIPAGVPVGMSAYYAHRDPSVFPRPDEFLPERWLSNVTPEMSRNYVPFSRGSRRCLGMNLAYAEINHVIATLFRPGGPDFKLYETSEKDVKPAHDLIVPLPSLESKGFRVIFR
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the sesterterpenes ophiobolins, fungal phytotoxins with potential anti-cancer activities (PubMed:23324037, PubMed:27116000).  The first step of the pathway is performed by the sesterterpene synthase oblA that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylfarnesyl diphosphate (GFPP) and further converting GFPP into ophiobolin F, respectively (PubMed:23324037).  Other sesterterpenoids (C(25) terpenoids) are found as minor products of oblA (PubMed:23324037).  It is expected that ophiobolin F is then oxidized to ophiobolin A via ophiobolin C and ophiobolin B intermediates by the combined action of the cytochrome P450 monooxygenase oblB and the FAD-dependent oxidoreductase oblC (Probable).  Although oblB catalyzes multistep oxygenations at C5 and C21/C7 in a relatively efficient manner, it is unable to convert ophiobolin F to ophiobolin C and produces instead several unexpected derivatives (PubMed:27116000).
What are the official names of this protein?
Cytochrome P450 monooxygenase oblB, Ophiobolin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EX7L_CERSK
Sequence: MSDLFEDPAPSRNTPEFTVSELSGAVKRVIEGEFGLVRVRGEIGRVSRPASGHLYFDLKDDRAVMAAICWKGQAGRLSVRPEEGMEVVATGRMTTFPGQSKYQIIVEDMAPAGAGALMAMLEKRRAALAAEGLFDAARKRPLPYLPRVIGVVTSPSGAVIRDILHRLRDRFPSHVLIWPVAVQGEKCAPEVAAAIRGFNALPEGGPIPRPDLLIVARGGGSLEDLWGFNEEIVVRAAAESRIPLISAVGHETDTTLIDHAADRRAPTPTAAAEMAVPVRLELLAGLDGQGARLSRCAAETIRRRDQRLRDLARALPRLESLVAGPSQRFDLWSGRLSGALGQSVAARRARLEPLGAHLRPRLLADLVARQKDRLGDRTRSLETCLGRRAERARDRFEALSARLAPAFARLIAETERATRRDAATLGTLAARLDAAPEARLARLSDRLEALDRLRQTLGYRETLKRGYAVVRADGAVVTTKAEAGTAAVLEIEFQDGRLSVGRGKTRKPKEEPPAQGSLL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGIB_SALPA
Sequence: MKRTKSIHHASFRKSWSARHLTPVALAVTAVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTAAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDAAGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSAAGTSTRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: PRMA_LEGPH
Sequence: MWFQLKIEHCPNDKIEEITEELEECGALSITLTDKNDNPVLEPEPGTTPLWPEVIIHALFAQAEEAQYAREQLVAKRPSLHCSLELLADKNWERAWMDDFRPQRFGNRLWVCPTWLPPPEPDAVNLILDPGLAFGTGTHATTSLCLTWLEQADLKNKSIIDYGCGSGILSLAAIKLGAKHVYAVDIDNQALQATQSNAHANHITESQLSISFPEALQNPVHLVIANILLAPLISLKERFHQLLPSGAHLVTSGILEEQAPLLIDAYDSAFTHIATEYCEGWSLLVFTSK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUHB_RHIME
Sequence: MARSALLNVMVQAVFKAGKSLARDFGEVQNLQVSLKGPADYVSQADRKAERIIREELMKARPTYGFLGEEGEEIKGTDGAHRWIVDPLDGTTNFLHGIPHFAISVALERQGEIVGAVVFNPATDELYTAERGGGAFLNDRRLRVGARKALSDAVIGTGTPHLGRGNHGKYLVELRHVMGEVAGIRRMGSASLDLAYVAAGRFDGFWERDLAAWDMAAGLLLIREAGGWSTDAEGGGKPLEAGSIVCGNEHIAKALREVIQRPIPSK
What are the official names of this protein?
Inositol-1-monophosphatase, I-1-Pase, IMPase, Inositol-1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: RS21_RALSO
Sequence: MTTIRLKENEPVEVALRRFRREIERTGLIKELRARTAYEKPTTERKRKKAAAVSRTRKRLRSQMLPKKLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: HBEAG_HPBDB
Sequence: MWNLRITPLSFGAACQGIFTSTLLLSALTVPLVCTIVYDSCLYMDINASRALANVYDLPDDFFPKIDDLVRDAKDALEPYWKSDSIKKHVLIATHFVDLIEDFWQTTQGMHEIAESLRAVIPPTTAPVPTGYLIQHEEAEEIPLGDLFKHQEERIVSFQPDYPITARIHAHLKAYAKINEESLDRARRLLWWHYNCLLWGEANVTNYISRLRTWLSTPEKYRGRDAPTIEAITRPIQVAQGGRKTSSGTRKPRGLEPRRRKVKTTVVYGRRRSKSRDRRAPSPQRAGSPLPRSSSSHHRSPSPRK
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: OPGH_KLEP7
Sequence: MNKITKYIDALPLSDAEKSALPDTSLQAVHQALDDDHQTFAREDDSPLGSVKARLAHSWPDSLSGDQLVKDDEGRTQLHAMPKAKRSSMIPDPWRTNPVGRFWDRLRGRDVTPRYLSRLTQEERESEQKWRTVGTIRRYILLLLTLSQTVVATWYMKTILPYQGWALINPADMVGQNLWISFMQLLPYVLQSGILILFAVLFCWVSAGFWTALMGFLQLLIGRDKYSISASTVGDEPLNPAHRTALIMPICNEDVDRVFAGLRATWESVKATGNAAHFDVYILSDSYNPDICVAEQKAWMELIAEVQGEGQIFYRRRRRRVKRKSGNIDDFCRRWGSQYSYMVVLDADSVMTGECLSSLVRLMEANPNAGIIQSSPRASGMDTLYARCQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGNFAGSILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCQGNLMNFRLFLVRGMHPVHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPELAIALFASTMVLLFLPKLLSIILVWCKGPKEYGGFFRVTLSLLLEVLFSVLLAPVRMLFHTVFVVSAFLGWEVVWNSPQRDDDSTPWGEAFMRHGSQLLLGLVWAVGMAWLDLRFLFWLAPIVVSLILSPFVSAISSRATVGLRTKRWKLFLIPEEYSPPQVLKDTDAYLTMNRQRSLDDGFMHAVFNPSFNALATAMATARHRQGHILEIARERHVEQALNETPDKLNRDRRLVLLSDPVTMSRLHYRVWAAPEKYSSWVNAYQQLALNPLALKTK
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPD_ENDTX
Sequence: MKNAAIIAAAGSGKRFGSRVSKQFLNLSGKPVFLWSVEAFASIKSFKQIIVVVPSDMVEFLSLKYKTGFVCATGGNERFDSVKNGLALVGDDIDFIAVHDASRPLISKKDILLVLEKAAKTKVAVAVEKAKDTVKLVSADGYILKTLDRTILRNAQTPQIFKTELLKRAYSRKMSAGTTDDSQLVENLKIKVSAVETKFLNFKITTKQDFELAEKILKS
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: NIFU1_ORYSJ
Sequence: MQTTTVPMAAAAAVAPSTTTSSSASFKVAAYAWSSCRSSSSPATRLVAAPNHQRPPLVVGAIAGLDPVTAVQLPLTAGNVESVLDQVRPYLTADGGDVALHEIAGNVVRLKLQGACGSCPSSLITIKRGIERRLMEKIPDVAAVEPVTDKETGLELNEENVEKVLNEIRPYLAGTGGGGLQFLMIKGPIVKVRLTGPAAVVRTVRIAVSKKLREKIPSIQIVQLLS
What is the function of this protein?
Molecular scaffold for [Fe-S] cluster assembly of chloroplastic iron-sulfur proteins.
What are the official names of this protein?
NifU-like protein 1, chloroplastic, OsNifu1.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y1321_PYRHO
Sequence: MQEYKELIKECAKELEGLMPEISQKLVNIAKINSPDRAFLEYLKVVEQVSLMKTERKQKNKALIILWRYGEALEKELYSDVKFFAKPLHKRIFRFVDWKIIGMLFLVFIILPAITSNLWSFRSEHYVLYLNENVDFPRELCNYRTSWLYDFRTSMVCVLKYGYGSINVTLRGNSWEKGVEAQRFISDMEYDFDRVKSPITYIQTPKETLRYKKGVCSDFALLVANILLDNNVSPVYIVHTVVRKEPSGGHAAAGIYVNGTLWILDWGSKPTKFQEYLENIDRIWEIREVRIYRITRDRITLERIYKARLEDDRWRFLYSVIIMLGIFILKRREWWIM
What are the official names of this protein?
UPF0252 protein PH1321.
What is the protein family that this protein belongs to?
Belongs to the UPF0252 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: S52A1_HUMAN
Sequence: MAAPTLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKDLPEGWSLPSYLSVVVALGNLGLLVVTLWRQLAPGKGEQVPIQVVQVLSVVGTALLAPLWHHVAPVAGQLHSVAFLTLALVLAMACCTSNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALVQGVGRLECPPAPTNGTSGPPLDFPERFPASTFFWALTALLVTSAAAFRGLLLLLPSLPSVTTGGSGPELQLGSPGAEEEEKEEEEALPLQEPPSQAAGTIPGPDPEAHQLFSAHGAFLLGLMAFTSAVTNGVLPSVQSFSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLVGLSLLGMLFGAYLMALAILSPCPPLVGTTAGVVLVVLSWVLCLCVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAGAMFPPTSIYHVFQSRKDCVDPCGP
What is the function of this protein?
(Microbial infection) May function as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).
What are the official names of this protein?
Solute carrier family 52, riboflavin transporter, member 1, Porcine endogenous retrovirus A receptor 2, PERV-A receptor 2, huPAR-2, Protein GPR172B, Riboflavin transporter 1, hRFT1.
What is the protein family that this protein belongs to?
Belongs to the riboflavin transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURA_METPB
Sequence: MANVVVVGAQWGDEGKGKIVDWLSEQADIVVRFQGGHNAGHTLVVGEAVYKLSLLPSGVVRPNTLGVIGNGVVLDPYALASEIDRLAGQGVTVTRENLRVADNATLILSLHRELDALREDGAPGTKIGTTKRGIGPAYEDKVGRRAIRLMDLAEPETLPPKIERLLAHHNALRRGFGLEEISETAILDELTAIADRVLPYQDTVWHLLDEARRGGKRILFEGAQGALLDVDHGTYPFVTSSNTVAGQAATGSGLGPRAIGYVLGIAKAYTTRVGEGPFPTELHDAIGQRIGERGHEFGTVTGRKRRCGWFDACLVRQTVQTSGIDGIALTKLDVLDGFDEIRVCTAYDIDGQRFDHLPASQAAQQRAVPVYETIPGWSGTTAGARSWADLPAQAIKYVRRIEELIGAPVALLSTSPERDDTILMHNPFED
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXE_SALA4
Sequence: MSEIKDIVVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTVSALRRWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPWLSALDGFSIGMGATGAMFVLGSLREILGNGTLFDGADSLLGGWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAVKYLIDEKMKKRRAETAPSAVPAGETGKV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rsx electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DRPB_ECOLI
Sequence: MEYGSTKMEERLSRSPGGKLALWAFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGALLGSIAWYTRPRPARSRRYE
What is the function of this protein?
Localizes to the septal ring in about 30% of observed cells before cell constriction occurs; localization occurs in low ionic strength medium (0 NaCl) and requires FtsZ but not FtsEX.  Overexpression partially restores correct FtsI localization to the division septum in an ftsEX deletion.  Isolated as a multicopy suppressor of an ftsEX deletion mutant; it does not suppress other cell division defects (e. g.  ftsA, ftsI, ftsQ or ftsZ).
What are the official names of this protein?
Cell division protein DrpB, Division ring protein B.
What is the protein family that this protein belongs to?
Belongs to the DrpB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the septal ring before constriction, only when cells are grown at low ionic strength.
Protein: PDXJ_PSEU2
Sequence: MTHSTRILLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVLLLKDVLQTRMNFEMGVTEDMLAFAERIRPAHICLVPETRQELTTEGGLDVAGQEARIKAAVERLAKIGCEVSLFIDADERQIAASKRVGAPAIELHTGRYADAQTPTEVAEELQRVADGVAFGLAQGLVVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKALIVAAAR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSC_BACTN
Sequence: MEEKNHIYPIFDRMMTREDKEELLGQHSVMIWFTGLSGSGKSTIAIALERELHKRGLLCRILDGDNIRSGINNNLGFSETDRVENIRRIAEVSKLFLDSGIITIAAFISPNNDIREMAANIIGKDDFLEVFVSTPLEECEKRDVKGLYAKARKGEIQNFTGISAPFEVPEHPALALDTSKLSLEESVNRLLEMVLPKIEKK
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: NCED9_ARATH
Sequence: MTIITIISGMYIYSLLSQDAHHSQYGQNTNLVLKKPIPKPQTAAFNQESTMASTTLLPSTSTQFLDRTFSTSSSSSRPKLQSLSFSSTLRNKKLVVPCYVSSSVNKKSSVSSSLQSPTFKPPSWKKLCNDVTNLIPKTTNQNPKLNPVQRTAAMVLDAVENAMISHERRRHPHPKTADPAVQIAGNFFPVPEKPVVHNLPVTGTVPECIQGVYVRNGANPLHKPVSGHHLFDGDGMVHAVRFDNGSVSYACRFTETNRLVQERECGRPVFPKAIGELHGHLGIAKLMLFNTRGLFGLVDPTGGLGVANAGLVYFNGHLLAMSEDDLPYHVKVTQTGDLETSGRYDFDGQLKSTMIAHPKIDPETRELFALSYDVVSKPYLKYFRFTSDGEKSPDVEIPLDQPTMIHDFAITENFVVIPDQQVVFRLPEMIRGGSPVVYDEKKKSRFGILNKNAKDASSIQWIEVPDCFCFHLWNSWEEPETDEVVVIGSCMTPPDSIFNEHDETLQSVLSEIRLNLKTGESTRRPVISEQVNLEAGMVNRNLLGRKTRYAYLALTEPWPKVSGFAKVDLSTGEIRKYIYGEGKYGGEPLFLPSGDGEEDGGYIMVFVHDEEKVKSELQLINAVNMKLEATVTLPSRVPYGFHGTFISKEDLSKQALC
What is the function of this protein?
Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity.  Catalyzes the first step of abscisic-acid biosynthesis from carotenoids.  Contributes probably to abscisic acid synthesis for the induction of seed dormancy.
What are the official names of this protein?
9-cis-epoxycarotenoid dioxygenase NCED9, chloroplastic, AtNCED9.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y549_MYCPN
Sequence: MINIDPHFIHNLTNKLKTFDNFSLYVHVNPDFDAFGAAFAFKAFLAVYFPHKKAYVMGSHNIKADGKDLFPFEAAPIDDAFVKNSLAIIFDTSNQERVLTQKHKLAKETVRIDHHPKTESFADLEWIDPAFSAAAEMVGYLILQMGYELNAEMAAYIYAGIITDTQRFSSSATTPQTFALTAKLLETGFNRNKVHDAVYLKPLLEHKYFSYVLNKAKITPNGLAYALLKKGTYKQFGVVSPLPMVHALNNIKGVKIWTTCYFNEDIKKWIGSIRSRSIPINNFAQMFGGGGHKYAAAFVLDDKRQFMKLVEIMDDFLAKQKHVNS
What are the official names of this protein?
Uncharacterized protein MG371 homolog.
What is the protein family that this protein belongs to?
Belongs to the mgp1/MG371 family.
Protein: RS14Z_MYCSS
Sequence: MAKKALVNKANKKPKFKVRGYTRCQRCGRPHAVFRKFGLCRICLREMAHAGELPGVQKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: AKP8L_MOUSE
Sequence: MSYTGFVQGSETTLQSTYCDTSAQPTCDYGYGTWNSGTNRGYENYGYGYGYGQDNTTNYGYGMATSHSWEMASSDTNANPSASGSASADSVLSRINQRLDMMPHLETDMIQGGVYGSGGGERYDSYEACDSRAILSERDLYRSSYDYGELDPEMEMAYEGQYDAYRDQFRMRGGDTFGPRAQGWARDARSGRPMASGYGRMWEDPMGARGQCMPGASRLPSLFSQNIIPEYGMFQGMRGGGAFSGGSRFGFGFGNGMKQMRRTWKTWTTADFRTKKKKRKQGGSPDEPDSKATRTDCSDNSDSDNDEGTEGEAAEGTESAEAMEKGSRVDGEDEEGKEDGREEGKEDPEKGALTAQDESSQAKRKLQASKKSQDKQKKRQRDRMVERIQFVCSLCKYRTFYEDEMGSHLDSKFHKEHFKYVGTKLPKQTADFLQEYVTNKTKKTEELRKTVEDLDGLIQQIYRDQDLTQEIAMEHFVKKVEAAHCAACDLFIPMQFGIIQKHLKTMDHNRNRRLMMEQSKKSSLMVARSILNNKLISKKLERYLKGENPFTDNPEEEKEQDEVEAGALDEGAPSEATELTEGVPAQPPVPLEPAPGTTTPPPPPPPEEEESPVPLLGGALQCQIRGIPGLDMEDDEEGGGGP
What is the function of this protein?
Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9.  Increases CTE-dependent nuclear unspliced mRNA export.  Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA.  May be involved in nuclear envelope breakdown and chromatin condensation.  May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis.  May regulate the initiation phase of DNA replication when associated with TMPO isoform Beta.  Required for cell cycle G2/M transition and histone deacetylation during mitosis.  In mitotic cells recruits HDAC3 to the vicinity of chromatin leading to deacetylation and subsequent phosphorylation at 'Ser-10' of histone H3; in this function seems to act redundantly with AKAP8.  May be involved in regulation of pre-mRNA splicing (By similarity).
What are the official names of this protein?
A-kinase anchor protein 8-like, AKAP8-like protein, Neighbor of A-kinase-anchoring protein 95, Neighbor of AKAP95.
What is the protein family that this protein belongs to?
Belongs to the AKAP95 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus matrix. Nucleus speckle. Nucleus, PML body. Cytoplasm. Note=Colocalizes with PRPF40A in the nuclear matrix. Nuclear at steady state but shuttles between the nucleus and cytoplasm. The shuttling property has been questioned. Colocalizes with EBNA-LP in PML bodies.
Protein: ATPA_PORPU
Sequence: MVNIRPDEISSIIRQQIEKYDQDVEVANIGTVLQVGDGIARVYGLDEVMAGELLEFEDKTIGVALNLESDNVGVVLMGDGRDILEGSSVKGTGKIAQIPVGDAFLGRVVDPLARPIDNKGEPASNGTRLIESMAPGIIGRQSVCEPMQTGITAIDSMIPIGRGQRELIIGDRQTGKTAVALDTIINQKGQDVVCVYVAIGQKASSVAQVVSSLQEKGALDYTIIVTANADSPATLQYIAPYTGAALAEYFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNSDLGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSGDLFNSGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFSQFASDLDKATQNQLARGQRLREILKQAQNSPIPVEEQTAIIYTGINGYLDDIAVNKVPDFIIKLREDLKNSKPEFGESIRSSKKLDTASEELLKKAIEDVKQGFVKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PCKA_YERPA
Sequence: MSVKGITPQELAAYGIHNVSEIVYNPSYDLLFEEETKPTLEGYERGTLTTTGAIAVDTGIFTGRSPKDKYIVRDAITQDTVWWADQGKGKNDNKPLSQEIWNHLKGLVTEQLSGKRLFVVDTFCGANADTRLQVRFITEVAWQAHFVKNMFIRPSDEELARFEPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEKGDVAIFFGLSGTGKTTLSTDPKRKLIGDDEHGWDDDGVFNFEGGCYAKTIKLSEEAEPDIYHAIKRDALLENVVVLADGTVDFNDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTANQTQYHFLSGFTAKLAGTERGVTEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAVGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGEIDKAETFTLPIFDLAVPMALPGVNPDILDPRDTYADKAQWQEKAEDLAKRFATNFDKYTDTPAGAALVSAGPKI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INSH4_ECOLI
Sequence: MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRARVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH
What is the function of this protein?
Involved in the transposition of the insertion sequence IS5.
What are the official names of this protein?
Transposase InsH for insertion sequence element IS5F.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: ATRF2_STAHJ
Sequence: MTEKEKMLAHQWYDANFDKDLETERVRAKDLCFDFNQTRPSDDSRRQAILTELFGYTLENVAINSPFDTDYGWNVKLGKNVFVNSNCYFMDGGGITIGNDVFIGPSCGFYTAHHPLTPKERNAGLELAQPITIGNNIWFGGNVVVTPGVTIGDGSVIAAGSVVTKDVPPNSLVAGVPAKVIREINENDAPKN
What are the official names of this protein?
Putative acetyltransferase SH0499.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: CNGK1_RHILO
Sequence: MSVLPFLRIYAPLNAVLAAPGLLAVAALTIPDMSGRSRLALAALLAVIWGAYLLQLAATLLKRRAGVVRDRTPKIAIDVLAVLVPLAAFLLDGSPDWSLYCAVWLLKPLRDSTFFPVLGRVLANEARNLIGVTTLFGVVLFAVALAAYVIERDIQPEKFGSIPQAMWWAVVTLSTTGYGDTIPQSFAGRVLAGAVMMSGIGIFGLWAGILATGFYQEVRRGDFVRNWQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVEGSVSVATPNPVELGPGAFFGEMALISGEPRSATVSAATTVSLLSLHSADFQMLCSSSPEIAEIFRKTALERRGAAASA
What is the function of this protein?
Cyclic nucleotide-regulated potassium channel activated by cAMP.
What are the official names of this protein?
Cyclic nucleotide-gated potassium channel mll3241, MlotiK1 channel.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSPB_BACSU
Sequence: MLEGKVKWFNSEKGFGFIEVEGQDDVFVHFSAIQGEGFKTLEEGQAVSFEIVEGNRGPQAANVTKEA
What is the function of this protein?
Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA, and also to other sequences.  Has greater affinity for ATTGG than CCAAT.  Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions.
What are the official names of this protein?
Cold shock protein CspB, Major cold shock protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Shows transcription-dependent localization at subcellular sites surrounding the nucleoid.