PharMolix/UniProtQA huggingface dataset:
Protein: SP100_MUSCR
Sequence: MEDSNASPRMSTEHENTEMHPFEYMFKHFKTQKVAISNAIRSTFPFLESLRDREFITGKMYEDLIDSCRSLVPVDKVIYKALDELEKKFDVTVLWELFNEVNMEKYPDLNPIRRSFECVFPNELSFQGIDRGNPNSQLSLEQGPSASYSQGSLNGSSLDLSSSEGWRSNDRRNSNLMQANQTENHQLAESPGHLDSCELQVQLNNGDATPESYSLLPQHEERAVQLNNEFQINPCFVQLIDVKKENSSFSLAGNQQTRARTNQNEDSEVIELSSGDSDDGENFSEATTTIPSQPAPAYSRTPPTLRTDRRGDTSDTESSIIIRRRKRTGRKKRERLGSYLIRNIKIPMKTSWKTAVLARSANTSSQRRRKRGPRIPREENADFGGAELPAVCGNVQGFLNKEKFKQGIYVRSIRSETGRLFTPMDFEIEGNCEKAKNWRQTIRCKGWTLRELIQKGVLQDPPRKKKENPRNPRQMKRQVNAL
What is the function of this protein?
Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis.  Functions as a transcriptional coactivator of ETS1 and ETS2.  Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA.  Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion.  Through interaction with the MRN complex it may be involved in the regulation of telomeres lengthening.  May also regulate TP53-mediated transcription and through CASP8AP2, regulate FAS-mediated apoptosis.  May also play a role in infection by viruses through mechanisms that may involve chromatin and/or transcriptional regulation (By similarity).
What are the official names of this protein?
Nuclear autoantigen Sp-100, Nuclear dot-associated Sp100 protein, Speckled 100 kDa.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Cytoplasm. Note=Accumulates in the cytoplasm upon FAS activation.
Protein: HUTU_GEOKA
Sequence: MAEKRTVSPPAGTERRAKGWIQEAALRMLNNNLHPDVAERPDELIVYGGIGKAARNWECYEAIVDTLLRLENDETLLIQSGKPVAVFRTHPDAPRVLIANSNLVPAWATWDHFHELDKKGLIMYGQMTAGSWIYIGSQGIVQGTYETFAEVARQHFGGTLAGTITLTAGLGGMGGAQPLAVTMNGGVCLAIEVDPARIQRRIDTNYLDTMTDSLDAALEMAKQAKEEKKALSIGLVGNAAEVLPRLVEMGFVPDVLTDQTSAHDPLNGYIPAGLTLDEAAELRARDPKQYIARAKQSIAAHVRAMLAMQKQGAVTFDYGNNIRQVAKDEGVDDAFSFPGFVPAYIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFSDNERLCHWIRMAQKRIKFQGLPARICWLGYGERAKFGKIINDMVAKGELKAPIVIGRDHLDSGSVASPNRETEGMKDGSDAIADWPILNALLNAVGGASWVSVHHGGGVGMGYSIHAGMVIVADGTKEAEKRLERVLTTDPGLGVVRHADAGYELAIRTAKEKGIDMPMLK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEEX_SALNS
Sequence: METTKPSFQDVLEFVRLFRRKNKLQREIQDIEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKSDYEDRVDDYIIKNAEISKERRDISKKLKAMGEMKHADVKAE
What are the official names of this protein?
UPF0265 protein YeeX.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: AKIRB_XENLA
Sequence: MACGATLKRSMEFEALMSPQSPKRRRCAPLPGSPATPSPQRCGIRPEIQQGQQQPLGGDLRLTPEQILQNIKQEYTRYQRRRQLEGAFNQGEAGVSNEVQASCSSLTAPSSPGSLVKKDQPTFSLRQVGILCERLLKDHEDKIREEYEQILNIKLAEQYESFVKFTHDQIMRRYGARPTSYVS
What is the function of this protein?
Molecular adapter that acts as a bridge between proteins, and which is involved skeletal muscle development.  Functions as signal transducer for MSTN during skeletal muscle regeneration and myogenesis.
What are the official names of this protein?
Akirin-1B.
What is the protein family that this protein belongs to?
Belongs to the akirin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTEN_DICDI
Sequence: MSNLLRVAVSKQKRRYQKNGYDLDLAYITDNIVAMGFPSEKVEGVFRNPMKDVQRFLDQYHKDHFKVYNLCSERVYDHSKFYGRVGYYPFDDHNAPQFEMIDAFCRDVDAWMKEDSKNIAVIHCKAGKGRTGLMICCWLMYCGMWKNTEDSLRFYAALRTYNQKGVTIPSQIRYVGYFGRSIRESIKYVPRNVTLKKIVLRPLPKEINLSEVQFNISVGKNCVFNSKEHNMNVVISKKKKTVVDKNKKDPKKKLTKENSEKNIDSQQQQQSQSSLSQSQQGQSSPNMQSLSASGTISSGSNVGTVNGNTLHQLGGSQFSLSDLADGNTIGNDEYISFEIGALSLAGDIRIEFTNKQDDRMFMFWVNTSFVQQLEIIPKSGLDKAHKDKNHKAFPEDFHVELTFDQLDQQQSHTTVVASAEEQTNNQHYPQSSNNVATSSSHHDNITVVASDAPQNNNNNNNLNSSNSNNATTTTTKNNISLASSQSNPVQQESNPSTTTQVSEENSAPKVEAEKIENSNASANDSETSSNSSS
What is the function of this protein?
Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins.  Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate (By similarity).  Negative regulator of PI3K chemotaxis pathways.  Overexpression leads to a suppression of a PI3K-dependent activation of pkbA, and these cells exhibit chemotaxis defects consistent with a reduction in PI3K activity.
What are the official names of this protein?
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Pten 3-phosphoinositide phosphatase alpha.
What is the protein family that this protein belongs to?
Belongs to the PTEN phosphatase protein family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cytoplasm, cell cortex. Note=Found uniformly on the plasma membrane in unstimulated cells. In response to chemoattractant stimulation, there is a rapid and transient release from the plasma membrane. Constitutively localized in the cortex of polarized cells.
Protein: WASL_RAT
Sequence: MSSGQQPPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQLYAADRNCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDAPNGPNLPMATVDIKNPEITTNRFYSSQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPGVVVPPPPPNRMYPPPPPALPSSAPSGPPPPPPLSMAGSTAPPPPPPPPPPPGPPPPPGLPSDGDHQVPASSGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVSDGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDDDDEEDFQDDDEWED
What is the function of this protein?
Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex.  Involved in various processes, such as mitosis and cytokinesis, via its role in the regulation of actin polymerization.  Together with CDC42, involved in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia.  In addition to its role in the cytoplasm, also plays a role in the nucleus by regulating gene transcription, probably by promoting nuclear actin polymerization (By similarity).  Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.  Plays a role in dendrite spine morphogenesis (By similarity).
What are the official names of this protein?
Actin nucleation-promoting factor WASL, Neural Wiskott-Aldrich syndrome protein, N-WASP.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Cytoplasm. Note=Preferentially localized in the cytoplasm when phosphorylated and in the nucleus when unphosphorylated (By similarity). Exported from the nucleus by an nuclear export signal (NES)-dependent mechanism to the cytoplasm (By similarity).
Protein: RS4_LIGS1
Sequence: MSRYTGPSWKVSRRLGFSLSGTGKELSRRPYAPGQHGQDRRGSLSEYGLQLREKQKLRMTYGLTERQFSNLFKRAGKIREGKHGDNFMILLERRLDNVVYRLGLASTRRQARQLVNHGHITVDGKRVDIPSYEVEPGQVISLRERSKDLQIVKEALEAVVGRVPFVNFDENKMEGTLVRLPDREELDANIDEALVVEFYNR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ARF5_ARATH
Sequence: MGLLSIIRKIKKKEKEMRILMVGLDNSGKTTIVLKINGEDTSVISPTLGFNIKTIIYQKYTLNIWDVGGQKTIRSYWRNYFEQTDGLVWVVDSSDLRRLDDCKMELDNLLKEERLAGSSLLILANKQDIQGALTPDEIGKVLNLESMDKSRHWKIVGCSAYTGEGLLEGFDWLVQDIASRIYMLD
What is the function of this protein?
Has a role in the cofactor-dependent pathway of microtubule biogenesis.  Not essential for cell viability.  May play a regulatory role in sequestring TFCD.
What are the official names of this protein?
ADP-ribosylation factor-like protein 2, Protein ARF-like 2, Protein HALLIMASCH, Protein TITAN 5.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INH_SERMA
Sequence: MKGTLTRAALAAGGMMVTSAVMAGSLALPTAQSLAGQWEVADSERQCQIEFLANEQSETNGYQLVDRQRCLQSVFAAEVVAGAGPDGIALLQADGSTLAFFSRDGDLYRNQLGAGDALTLKALA
What is the function of this protein?
Inhibitor of the alkaline protease.  Inhibits SMP by formation of a non-covalent complex with a molar ratio of 1:1 and shows a high specificity.
What are the official names of this protein?
Alkaline proteinase inhibitor, 11 kDa protease inhibitor, SmaPI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I38 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FOLD1_SACEN
Sequence: MTTIPSSATSATKTLGGTELARGIRAEVTSAAAELTLLGVTPRLAVVVATDDESSAWYVRSIARAAAKSGLLCDIVDLGADATTQSIRAELQRLSADPAVHGIILQTPLPAGANFEDLAASIAPDKDVDGANPLSLGRLAAGLPAYAPATAAAVLALLDHHEVPLAGRTGVVVGRSNVVGKPAAQLLLQRDATVTVCHRYTQNLGHHTRTADVLVVAVGRPGLITAQHVAEHTVVIDVGTNPTDDGGLVGDVDETSVSGRVAGLTPVPGGVGPVTTALLLQHTIQSASRSEPS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL2_ANAMF
Sequence: MSLKVLNPVTPSLRGTVMVNRVALWRGKPEKSLVVGRVSSGGRNAHGVITVRHRGGGHKRLHRVVDLKRNKDGVQAVVQRLEYDPNRTAFLALVRYEDGELSYILAPDGLKVSDVVVSGVGSDVLPGNCLQLGSIPAGTFVHNVELRPCGGGIIARAAGSYAQVMGRDGAYVLLRLGSGEVRKILALCRATVGVVSNLNNQNIKLGKAGRNRWLGFRPTVRGVAMNPVDHPHGGGEGKTSGGRNSVTPWGVPTKGKKTRKRGKHSDKYIKVSSVRKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HISX_CORJK
Sequence: MTSAQLDFSRIDLRGQAPTTAELRHRLPRGGTDVDSVIPTVAPIVDQVREGGARAALEIGQRFDGVTPDSVRVPAEVIDAAVGTLADDVIAALEEAIKRVRAFHSAIRPEDKQVEVAPGGIVTERFIPVQRVGLYAPGGNAVYPSSVIMNVVPAQEAGVESLVVASPPQEGGWPHPTVLAACKLLGVDEVWAVGGAQAVALLAHGSTAEGGEELEPVDMVTGPGNIFVTAAKRLCRSVVGIDSEAGPTEIAVLADESANAVEIAYDLISQAEHDTMAASVLITDSEKLADEVVAEMNERYHITENSERVAEALSGQQSGVVLVDDIAAGIRAANAYGAEHLEIHTEDAHGVAAQITNAGAIFIGRFSPVPLGDYAAGSNHVLPTSGTARHSSGLSTLTFLKSVHVIDYNEEGLRGVADTVITLSKSEGLPAHGEAISARTSTANTNGTEV
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: TRUD_KLEP3
Sequence: MIAFDQLTWLHGKPQSSGLLKANPEDFLVVEDLGFAPDGEGEHVLVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSKFQLEGCQVLEYARHKRKLRLGALKGNQFTVILREISHRQDVETRLQAIAERGVPNYFGAQRFGIGGSNLQGALRWAESDAPVRDRNKRSFWLSAARSALFNQQVSIRLKKTEFNQVVDGDALQLAGRGSWFVVTPEELEVSQARVHNRELMITAALPGSGDWGSQRDALAAEQAAIAEETSLQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTTGDYANIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: CH076_HUMAN
Sequence: MDSGCWLFGGEFEDSVFEERPERRSGPPASYCAKLCEPQWFYEETESSDDVEVLTLKKFKGDLAYRRQEYQKALQEYSSISEKLSSTNFAMKRDVQEGQARCLAHLGRHMEALEIAANLENKATNTDHLTTVLYLQLAICSSLQNLEKTIFCLQKLISLHPFNPWNWGKLAEAYLNLGPALSAALASSQKQHSFTSSDKTIKSFFPHSGKDCLLCFPETLPESSLFSVEANSSNSQKNEKALTNIQNCMAEKRETVLIETQLKACASFIRTRLLLQFTQPQQTSFALERNLRTQQEIEDKMKGFSFKEDTLLLIAEVMGEDIPEKIKDEVHPEVKCVGSVALTALVTVSSEEFEDKWFRKIKDHFCPFENQFHTEIQILA
What are the official names of this protein?
Uncharacterized protein C8orf76.
Protein: SYL_STRGG
Sequence: MSETNSAAETAAPHRYTAAMAADIEARWQDFWDAEGTYEAPNPTGDLAGDPELAARPKKFIMDMFPYPSGAGLHVGHPLGYIATDVYARHQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANMENMKVQLRRLGLGHDNRRSFATIDSEYYKWTQWIFLQIFNSWYDSEADRARPIAELVEQFENGTRATPDGREWGALSAAERADLLSEYRLAYASDAPVNWSPGLGTVLANEEVTADGRSERGNFPVFKAKLRQWNMRITAYADRLLNDLDGLDWPEAIKLQQRNWIGRSEGARVEFPVDTAGGITVFTTRQDTLFGATYMVLAPEHDMVERIIPAAWPEGTHPVWTGGHASPAEAVTAYRKQAAAKSDVERQAEAKDKTGVFTGAYATNPVSGEKVPVFIADYVLMGYGTGAIMAVPAHDARDFAFARAFELPMRCVVQPSDDRGTDPATWDDAFSSYDAKLVNSANDEISLDGLGVVEAKARITEWLKEHGVGEGTVNFRLRDWLFSRQRYWGEPFPIVYDEDGIAHPLPESMLPLELPEVEDYSPRTFDPEDATAQPETPLSRNADWVNVTLDLGDGAGPRKYRRETNTMPNWAGSCWYELRYLDPNNDRQLVDPSIEQYWMGPREGQPTGGVDLYVGGAEHAVLHLLYARFWSKVLHDLGHISSAEPFHKLYNQGMIQAFVYRDSRGIAVPAAEVEERDGAFYHAGEKVSRVLGKMGKSLKNAVTPDEICAEYGADTLRLYEMAMGPLDVSRPWDTRAVVGQYRLLQRLWRNVVDEATGEVTVVDTEPDEDTLRALHKAIDGVGQDMAGMRFNTAIAKVTELNNHLTKAGGPLSRSVAERLVLLIAPLAPHIAEELWRRLGHADSVVHQDFPVADPAYVVDETVTCVVQIKGKVRARLEISPAITDEELEALALADEAVVAALGGAGIRKVIVRAPKLVNIVPA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTR2_ANOGA
Sequence: MLRKVFAVVSVLLVVSAAKVTKLVLDDHYVNRVVGGEVAKNGSAPYQVSLQVPGWGHNCGGSLLNNRWVLTAAHCLVGYEPSDLMVLVGTNSLKEGGELLKVDKLLYHSRYNRPQFHNDIGLMRLEQPVQFSELVQSVEYLEKAVPVNATVRLTGWGRTSTNGNVPTLLQSLNVVTLSNEDCKAKMGNPKNVDLGHVCTLTKAGEGACNGDSGGPLVYEGKLVGVVNFGVPCGRGFPDGFARVSYYHEWVRTTMANNS
What are the official names of this protein?
Chymotrypsin-2, AnChym2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: IL3RA_HUMAN
Sequence: MVLLWLTLLLIALPCLLQTKEDPNPPITNLRMKAKAQQLTWDLNRNVTDIECVKDADYSMPAVNNSYCQFGAISLCEVTNYTVRVANPPFSTWILFPENSGKPWAGAENLTCWIHDVDFLSCSWAVGPGAPADVQYDLYLNVANRRQQYECLHYKTDAQGTRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILTPPNMTAKCNKTHSFMHWKMRSHFNRKFRYELQIQKRMQPVITEQVRDRTSFQLLNPGTYTVQIRARERVYEFLSAWSTPQRFECDQEEGANTRAWRTSLLIALGTLLALVCVFVICRRYLVMQRLFPRIPHMKDPIGDSFQNDKLVVWEAGKAGLEECLVTEVQVVQKT
What is the function of this protein?
Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed:10527461).  Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation.  Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity).
What are the official names of this protein?
Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 5 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UREF_TRIV2
Sequence: MDTITLTDHHFLHILQLASSALPVGAYSYSEGLETLVESGTITSQSTLQQWLEAELSYGAIRLEAAVMVRSYQATIMGEMETLRYWNLWLSAARETQELRNSSWQMGRSLMQLLGKIQPEILSLANSVGNPCNYAIAFAIASAHWQVNIQAALLAYLHSWATNLITAGVKLIPLGQTAGQELLLQLQPLISHATVEIMSLKDDELSCCSWGLSLASMQHETQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPMT_FRAT1
Sequence: MNKLETNNNQYWLDRWQNDDVGFCQESPNEFLVKHFSKLNINDSSVCLIPMCGCSIDMLFFLSKGVKVIGIELSEKAVLSFFSQNTINYEVIHGNDYKLYKGDDIEIYVADIFNLPKIANNLPVFDIWYDRGAYIALPNDLRTNYAKMMLEVCSNNTQILLLVMEHDKKSQTPPYSVTQAELIKNFSAKIKFELIDSKQRDNIPDYRKAEGMTEQYYTTYLRKKQY
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_ACIBT
Sequence: MAKKGMINRELKREKTVAKYAAKRAELKATIANVNASDEERFEAMLKLQALPRNASPVRLRNRCGLTGRPHGYFRKFGLSRNKLRDTVMQGDVPGVVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: GCS2_ECOL5
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDTVKNQITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLMYKFNRFQACRYGLEGVITDPHTGDRRSLTEATLRLLEKIAPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: SEBOX_DANRE
Sequence: MALFYDQSFDLGLVQKINMETESDFIFNTNMLQFTDVTTKHMLSSPELDRTGHVEGQRKRKRTIFSRAQLSELERAFMITPYPDITLRERLAALTLLPESKIQVWFQNRRARSMKSKKLITPVSRRSPAKDCTFPATHPDLNLEQSPEANKSLRHHQQSLIRQALNPWPQNRPPISPDLPEILQWANRNSETPGDSSFSSCPSERIQHPFPNQSSSVWQMNCFAAHPEGLKSYCTTSQALYSSVSVDQMIPAHPSSLEEALQRQALTHYPQTSLGDISDLIYKAAVVTNLEEC
What is the function of this protein?
Probable transcription factor involved in the control of specification of mesoderm and endoderm.  Acts in parallel with bonnie and clyde, faust and casanova in the Nodal signaling pathway.
What are the official names of this protein?
Homeobox protein SEBOX, Homeobox OG-9, Homeobox transcription factor mezzo, Skin-, embryo-, brain- and oocyte-specific homeobox.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMM_MACCJ
Sequence: MEMNVGKIVNTHGVKGEVKILTASDFAAERFKPGKVLMIPFKNERVTLTIKSYRTHKNFHMLAFEGLNNINDVEKYKGLDVYQEIENEDIILDENEYFYSDIIGCTVFDGEREIGIVNDIFETGANDVWVVQGDKEYLIPYIEDVVKSIDIDNKKIIIEAIEGLL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_AYWBP
Sequence: MTLALQQTLKEAHLTPQEIDLVAVTQGPGLVGSLLVGINAANVFAYTYKKPLLGVNHLLGHIYSAQIEHEIKFPALVLLVSGGHTDLFYLTDHLQIKPLGTTIDDAVGEVYDKIAKNLNLPYPGGPLIDQLAQQGKDTYHLVRPYLKNDNLNFSFSGLKSTLVNLVMKQNLKDINIPDLCASFQTSVINVLCEKTKRALTKYHVKQLIVVGGVASNSGLRQKFMTSFSNLEVIFPSLQYCTDQAAMIGIAAYYQNQITKASKKYDLTAKPNLFF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction (By similarity).
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUI1_METM7
Sequence: MPEICPICGLPKDLCVCEEIAKEEQKIKVYVTKRRFGKLMTVVDGFDADLIDVKDLAKKLKDICACGGTVKKDSIELQGDHRRKAEETLIKMGFSKDMIDVR
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: FTHS_ALIF1
Sequence: MKSDIEICQTATLTRMKTIASNLGLHDDDITPQGPFKAKVNIDALKRLKSEPNGKLILVSAITPTPLGEGKTVTTIGLAQGLAKLGESVSACIRQPSMGPVFGVKGGAAGGGYSQVAPMEELNLHLTGDIHAITAAHNLASAAIDARIYHEQRLGYDVFSEKNELPALRIDPQHVVWKRVMDHNDRALRMVTIGKNEDGKTINGYEREDGFDITAASELMAILALATDLQDLRQRIGRIVVAYNLDGEPVTTEDLQVAGAMTVTMKFAINPTLMQTLEGVPTFVHSGPFANIAHGNSSIIADNIALKLTDYTVTEGGFGSDMGFEKACNIKAPLSEKSPDCAVLVATLRGIKANSGLFPLSPGQSLPKELFAPNKEALDAGLDNLLWHINNCAKYGLPVVVAINRFPEDTQEELDSLLNWVSNLDMNVDVAISEAFVKGGNGTLELAEKVIKACQQETQFTPLYTSEMSLFDKLNAVAIKGYGAERIELSEKAQQQLATFEKLGYQSLSVCMAKTPASISTDGNIKGAPTDFIVPIRELKLCAGAGFIYALCGNVMTMPGLPEKPAFMNLDIDGDGNIVGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: YGFZ_SALTI
Sequence: MAFISFPPRHPSSSARLPLTLIALDDWALSSITGVDSEKYIQGQVTADVSQMTEQQHLLAAHCDAKGKMWSTLRLFRERDGFAWIERRSVREAQLTELKKYAVFSKVVIAPDDERVLLGVAGFQARAALANVFSELPNSENQVVRDGASTLLWFEHPAERFLLVTDVATANMLTEKLHGEAELNNSQQWLALDIEAGIPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGKASRVPEAGEDLELQMGENWRRTGAILAATQLDDGQLLVQAVMNNDLEAESVFRVRDDANTLHIVPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.