PharMolix/UniProtQA huggingface dataset:
Protein: SHOT1_PONAB
Sequence: MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKAVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSVPDQQLSKALDENAKLTQQLEEERIQHQQKVKELKEQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSENSVPPPPPPPPPLPPPPPNPIRSFMSMIRKRSHPSGSGAKKEKATQPETPEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKTKPESSKGCESAVDELKGILASQ
What is the function of this protein?
Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth.  Mediates netrin-1-induced F-actin-substrate coupling or 'clutch engagement' within the axon growth cone through activation of CDC42, RAC1 and PAK1-dependent signaling pathway, thereby converting the F-actin retrograde flow into traction forces, concomitantly with filopodium extension and axon outgrowth.  Plays a role in cytoskeletal organization by regulating the subcellular localization of phosphoinositide 3-kinase (PI3K) activity at the axonal growth cone.  Also plays a role in regenerative neurite outgrowth.  In the developing cortex, cooperates with KIF20B to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex.  Involved in the accumulation of phosphatidylinositol 3,4,5-trisphosphate (PIP3) in the growth cone of primary hippocampal neurons.
What are the official names of this protein?
Shootin-1, Shootin1.
What is the protein family that this protein belongs to?
Belongs to the shootin family.
What are the subcellular locations of this protein?
Perikaryon. Cell projection, axon. Cell projection, growth cone. Cytoplasm, cytoskeleton. Cell projection, filopodium. Cell projection, lamellipodium. Note=Localizes in multiple growth cones at neurite tips before the neuronal symmetry-breaking step. Accumulates in growth cones of a single nascent axon in a neurite length-dependent manner during the neuronal symmetry-breaking step; when absent from the nascent axon's siblings, probably due to competitive transport, prevents the formation of surplus axons. Transported anterogradely from the soma to the axon growth cone in an actin and myosin-dependent manner and passively diffuses back to the cell bodies. Colocalized with L1CAM in close apposition with actin filaments in filopodia and lamellipodia of axonal growth cones in hippocampal neurons. Exhibits retrograde movements in filopodia and lamellopodia of axonal growth cones. Colocalized with KIF20B along microtubules to the tip of the growing cone in primary hippocampal neurons. Recruited to the growth cone of developing axon in a KIF20B- and microtubule-dependent manner.
Protein: RS3A_CANTT
Sequence: MAVGKNKRLSKGKKGLKKKVVDPFTRKDWFDIKAPTTFENRNVGKTLINRSTGLKNAADGLKGRVFEVCLADLQGSEDHSYRKIKLRVDEVQGKNLLTNFHGLDFTSDKLRSLVRKWQSLVEANVTVKTADDYVLRVFAIAFTKRQANQIKKTTYAQSSKLREVRKKMIEIMQREVSNCTLAQLTSKLIPEVIGREIEKSTQTIFPLQNVHIRKVKLLKQPKFDLGSLLALHGEGSTEEKGKKVSSGFKDVVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_JANMA
Sequence: MGQKIHPTGFRLAVSRNWASRWYAGNSNFATMLNEDLKVRAYLKTKLKNASVGRVVIERPAKNARITIYSSRPGVVIGKKGEDIEVLKSALTKMMGVPVHVNIEEIRKPETDAQLIADSIAQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARKEWYREGRVPLHTLRADIDYGFGEAETTYGIIGIKVWVYKGDRLANGEAPVIDVASDDDKKRRGPRRDDGKPSGRPRAPRPEGQPGAAAPGSAPAAKRVRAKKPDGAVDAAVSAEKAGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SYQ_CLOK5
Sequence: MGDNNNSSNFIKNIIIEDLKSGEYEKVVTRFPPEPNGYLHIGHAKSIVLNFSLADEFEGKVNLRFDDTNPSKEDVEYVESIKEDVKWLGYNWDNLCFASSYFERMYEYAVFLIKKGKAYVCDLTADEIREYRGTLTKPGKESPYRNRDVEENFKLFEGMKNGEFKDGEKVLRAKIDMASPNINMRDPVLYRIAHASHHNTGDRWCIYPMYDFAHPLEDAIEGVTHSICTLEFEDHRPLYDWIIQECEIENRPKQIEFARLNMTNTVMSKRKLKQLVDENFVDGWDDPRMPTIAGLRRRGFTPESIRNFCRAIGVSKASSIVDSQMLDYFLRDDLEKEAPRTMAILNPLKVVITNYPEGKTETFKIENNPDDASAGVREVPFSREIYIEQEDFMENPPKKYYRLFPGNEVRLKSAYFIKCTEAIKDKDGNVIELRCTYDPASKGGNSPDGRKVRGTLHWINVDTAIPAEIRLYEPLILEQQEKEGEEDLFLDHVNPNSLKVVKGFVEPDMKHVKSDEKFQFFRHGYFVLDGKCSKNGELVFNRIVSLKSSFKIPENK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NENF_HUMAN
Sequence: MVGPAPRRRLRPLAALALVLALAPGLPTARAGQTPRPAERGPPVRLFTEEELARYGGEEEDQPIYLAVKGVVFDVTSGKEFYGRGAPYNALTGKDSTRGVAKMSLDPADLTHDTTGLTAKELEALDEVFTKVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF
What is the function of this protein?
Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival (PubMed:31536960).  Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes (By similarity).  Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways (By similarity).  Neurotrophic activity is enhanced by binding to heme (By similarity).  Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity).
What are the official names of this protein?
Neudesin, Cell immortalization-related protein 2, Neuron-derived neurotrophic factor, Protein GIG47, Secreted protein of unknown function, SPUF protein.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space. Mitochondrion. Endoplasmic reticulum. Note=Localized to mitochondria and endoplasmic reticulum by PINK1 and PARK7.
Protein: TRPF_AGRRK
Sequence: MNPDIKICGLKTPEAMDRALERGATHVGFIFFEKSPRYIEPDLAGKLAERARGKAKIVAVTVNPTNDDLDEIISLVRPDILQLHGNESPERVLTIKAVYNLPVMKAMSVRDADDLKRVEAYIGIADRFLFDAKPPAGSELPGGNGVSFDWSLMSWLDDRVDYMLSGGVNKDNFAQALASTRATGIDLSSGVESAPGVKDPKKIDEFFDAVAEACLPEPAAGS
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: PEX13_MOUSE
Sequence: MASQPPPPPKPWESRRIPGAGPGPGSGPGPTYQSADLGPTLLTRPGQPTLTRVPPPILPRPSQQTGSNNVNTFRPAYSSFSSGYGAYGNSFYGSYSPYSYGYNGLGFNRLRVDDLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFSAFALVRTIRYLYRRLQWMMGLRRGSENEDLWAESEGTVACLSAEDQATNSAKSWPIFLFFAVILGGPYLIWKLLSTHNDEVTDNTNWASGEDDHVVARAEYDFVAVSDEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRRGRKTIESSTMLKQQQSFTNPTLIKGVTTTNPLDEQEAAFESVFVETNKVSSAPDSTGKNGDKQDL
What is the function of this protein?
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity).  The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity).  Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.  Involved in the import of PTS1- and PTS2-type containing proteins (By similarity).
What are the official names of this protein?
Peroxisomal membrane protein PEX13, Peroxin-13.
What is the protein family that this protein belongs to?
Belongs to the peroxin-13 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: NUOB_BEUC1
Sequence: MGIEEKAPSGFMLAKVSDLVGLIRKSSLWPVTMGLACCAIEMMATGTPRFDISRFGMEVFRASPRQADLMIVSGRVSQKMAPVVRQVYDQMSEPKWVLSMGVCASSGGMFNNYAVVQGVDHILPVDIYLPGCPPRPEMLLNAILELHEQIRSEPLGANRAEAARAVEAAALRATPTHEMTGLLA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GET1_YEAST
Sequence: MHWAAAVAIFFIVVTKFLQYTNKYHEKWISKFAPGNELSKKYLAKVKERHELKEFNNSISAQDNYAKWTKNNRKLDSLDKEINNLKDEIQSENKAFQAHLHKLRLLALTVPFFVFKIMYGKTPVYKLSSSTSTLFPTFVSGVWSQGWLYVLLHPLRTISQKWHIMEGKFGASKFDDMALQSVSLGIWVWALMNVINGVEFIVKQLFLTPKMEAPASVETQEEKALDAVDDAIILD
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.  Involved in mitochondrial distribution and morphology.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1, Mitochondrial distribution and morphology protein 39.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi- pass membrane protein.
Protein: RS17_DECAR
Sequence: MSESSSIKRTLIGRVVSDKMDKTVTVLVERKVKHPMYGKVMVRSKKYHAHNEGNSAKAGDLVEIVETRPVSRTKTWAVTSVLEKAIVV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RBSU_STAEQ
Sequence: MDFIAILIGLGPLLGWGLFPTIASKFGGRPVNQIFGATVGTLIFAIVLALFKGIGLPGGMALVFSLISGAGWAFGQIITFKAFELVGSSRAMPITTAFQLLGASLWGVFALGNWPGITNKIIGFLALLVILIGARMTVWTETKQQEYSKNLRSAVILLLVGEIGYWIYSAAPQATDIGGFKAFLPQAIGMVIVAVIYALMNMSKGNAFKEKVSWQQTISGFFFAFAALTYLISAQPNMNGLATGFVLSQTSVVLATLTGIFFLNQKKTSKELMITIVGLVLILVAASITVFIK
What is the function of this protein?
Could be involved in the uptake of ribose.
What are the official names of this protein?
Putative ribose uptake protein RbsU.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYG_ALKOO
Sequence: MATEKTMEKIVSLAKSRGFIFPGSEIYGGLANTWDYGPLGVELKNNVKKAWWKKFIQQSPYNVGLDAAILMNPKTWEASGHIGGFSDPLMDCKKCRSRFRADKLIEDYMHSQNEETVVDGWSNQQMKTYIEEKEIVCPECGAKDFTDIRQFNLMFKTFQGVTEDSSTEIFLRPETAQGIFVNFKNVLRTSRKKVPFGIGQIGKSFRNEITPGNFTFRTREFEQMELEFFCKPGEDLEWFNYWKEFCKNWLLNLNLTEENLRIRDHAEEELSHYSKATTDFEYRFPFGWGELWGVADRTDFDLKQHSEHSGEDFTYQDPITNEKYVPYCIEPSVGVDRVALAFLVDAYDEEVIDEKDTRVVLRLHPALAPFKAAVLPLTKKLKDQALELYETLSENYMVDYDEAGSIGKRYRRHDEIGTPFCITFDYDSLEDQCVTIRHRDSMEQERIQISELTTYLNEKLKF
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_ECOLU
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: FABZ_SOLUE
Sequence: MAILDINEIRAILPHRYPFLLVDRILEMETDRIVGIKNVTFNEPQFTGHFPDFPVMPGVMIVEAMAQTAGVLVLHSMPDRANKLVLLVAIENARFRKPVVPGDTLRMEMKIIKRKASVAKMAGIATVDGVVVAEAEVMCKLADKEEKPPAAPEIKVPAEAAV
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_MESM1
Sequence: MNHNEIIKYPLLTEKSYKTMAQNVYVFAVDRRARKIEIKDAIEFIFEVKVEKINLFNVPQKEKKVGRFKGLTNSYKKAYVYLREGKINIFPEEIEKEQKVEKQLIKEKSTSELKLEEKIAAKIAAKEQSEIKDEIVKSVPKKVTSIKKEITSKEVTPIKKTTSVKKETSPKEITSVKKTTTKEKDKTLVVAKKATIDTKVKSTTTKKTTTKKV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome (By similarity).
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NUOD2_BEII9
Sequence: MDEAGFRNFTVNFGPQHPAAHGVLRLVLELDGEVVERADPHIGLLHRGTEKLIEYRTYLQALPYFDRLDYVAPMNQEHAFCLAIEKLLQMPVPRRGQLIRVLFCEIGRLLSHLLNITTQALDIGALTPPLWGFEEREKLMVFYERASGARMHANYFRVGGVHQDLPEKLLDDIWNFCEPFLKVCNDLEELLSYNRIFKQRNVDVGVISLDEAWTRGFSGVMVRGSGAAWDLRKAQPYECYDELQFDIPVGKHGDCYDRYLIRMEEMRQSVRIMKQCLEKLSSVDGKGPIIEQNHKVTPPRRSEMKRSMEALIQHFKLYTEGHHVPAGEVYAAVEAPKGEFGVYLISDGSNIPYRCKIRAPSFAHLQAIDFLSHKHMLADVSAIIGSLDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2589_BACC2
Sequence: MNDLRYPIGQFTYKRPITEEMIDTWIQEIEDLPHELTKAIKDLDQKQLDTPYRVGGWTVRQVVHHVVDSHMNSYIRFKLALTEKNPTIKPYKEEKWAELPDSKLPVDVSLVMLDSLHKRWVNLLYSLEIEDLEKTFNHPETGETKLAVAIGLYAWHGRHHTAHITSLRKRLNW
What is the function of this protein?
Possible metal-dependent hydrolase.
What are the official names of this protein?
Putative metal-dependent hydrolase BCG9842_B2589.
What is the protein family that this protein belongs to?
Belongs to the metal hydrolase YfiT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUT4_SCHPO
Sequence: MDEKKALQYEESKRAEEITDIELVSVGGIDVEKKYGETKRALKSRHVQLIAIGGCIGTGLFVGSGSALSESGPASLFLSYVIMSFVIWTVMNALGEMCTYLPLSGASPITYIERYVDASLAFAAGWNYWYAYVFLVASEVTAASIVIEYWTYAVPTAGWIAILLFLVAVLNSFFVKWFGETEFWFAIIKVIAIVGLIILGVVIFFGGTPKHDRLGFRYWKHGLAFREYIVKGASGRFVGFWSAVIKSGFAFILAPELVIFSAGETEAPRRNIPKATSRFIYRLIFFYIFGSLTIGVITSSKDPRLLNAISSGASGAAASPFVIGIQNAEIPVLNHIINAVILTSACSSGNSFLFAGSRSIYSLAKEHQAPKIFKYCNRWGVPVISVAVTVLFACLAFLNASASAAVVFNWFCNLSTISGFLAWICVLVAYLQFRKAMILNNLWETRPYKTPFQPYATYLTLFLLALITLTNGFTVFVGHTFTAGNFIAAYITLPIFLVLYVAHKLWSRNWSFGKRIEEIDVTTGVAEAEALEQMYPAPVPRNIIEKIWFWIA
What is the function of this protein?
Required for high-affinity proline transport.  May be responsible for proline recognition and probably also for proline translocation across the plasma membrane.  Also functions as non-specific GABA permease.  Can also transport alanine and glycine (By similarity).
What are the official names of this protein?
Probable proline-specific permease put4.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
What are the subcellular locations of this protein?
Golgi apparatus. Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Protein: PYCA_METJA
Sequence: MFNKVLIANRGEIAIRIIRACWELGIKTVAVYSEADKRSLHATLADEAYCIGPAPAAKSYLNIDAILNVAEKAKVDAIHPGYGFLAENAEFARAVKKAGFEFIGPNPDAIEAMGSKINAKKIMKKAGVPLIPGSEGAIEDIDEAIEIAEAIGFPVVVKASAGGGGMGMSVAYSKEELKEVIESARNIAKSAFGDPTVFIEKYLENPRHIEIQLLGDKHGNIIHLGDRECSIQRRHQKLIEEAPSPIMTEELRERMGEAAIKAGKAINYDSAGTVEFLYENGNFYFLEMNTRIQVEHTVTEQVTGIDLVKAMIKIAAGEELTLKQEDVKIRGHAIECRINAEDPLNDFVPCPGKIKLYRSPGGPGVRIDSGVYGGAEIPPYYDSMIAKLITYGNSREEAIARMKRALREYVIIGVKTNIPFHRAVLEEENFLKGNISTHYVEQNMHKLREKMVKYALESRDLYSVVSEKVFEKNKKIAAAVGGLTMYISQIMKENEVNNKEW
What is the function of this protein?
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
What are the official names of this protein?
Pyruvate carboxylase subunit A, Pyruvic carboxylase A.
Protein: PSAE_SYNR3
Sequence: MAISRGDKVRIRRPESYWFNEVGTVASIDTSGIRYPVVVRFEKVNYNGFSGVDGGINTNNFAEAELDPA
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: EBI_DROME
Sequence: MSFSSDEVNFLVYRYLQESGFLHSAYVFGIESHISQSNINGALVPPAALLTILQKGLLYTEVEWSVGEDGEVARPIEGLSLIDAVMPEVKPLKPIVKTEPGKPGAVDSSAPAGGNQNNNAKPEIKIEPGTGVAGSAGGNKIAGSTTGTSTPTDQSASEVDSSGNAANNAGGTYAGNNGAGGNQASTGGSNSTSTPAGGDLAAPGASQKKSQNSNEAGSSSSGNAGNANATSTDDAASSTSTNGNSSTSSSVEQPTSGLTPAGGTVSTSNPDAAASGGASTATGSKAPSGAVTIRVGAQGNNVQSGSSNAQSSAPSGTISSSTSGGAGTPAALVPMDIDENIEIPESKARVLRGHESEVFICAWNPSRDLLASGSGDSTARIWDMSDANTNSNQLVLRHCIQKGGAEVPSNKDVTSLDWNCDGSLLATGSYDGYARIWKTDGRLASTLGQHKGPIFALKWNKCGNYILSAGVDKTTIIWDASTGQCTQQFAFHSAPALDVDWQTNQAFASCSTDQRIHVCRLGVNEPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLKIWSMNRDRCCHDLQAHSKEIYTIKWSPTGPGTNNPNTNLILASASFDSTVRLWDVERGSCIHTLTKHTEPVYSVAFSPDGKHLASGSFDKCVHIWSTQTGQLVHSYKGTGGIFEVCWNSKGTKVGASASDGSVFVLDLRKF
What is the function of this protein?
F-box-like component of E3 ubiquitin ligase complexes; involved in R7 photoreceptor cell differentiation, cone cell development and neuronal cell cycle control.  E3 ubiquitin ligase complexes mediate ubiquitination and subsequent proteasomal degradation of target proteins.  Required for specification of R7 photoreceptor cell fate in the eye by participating in the ubiquitination and subsequent proteasomal degradation of Tramtrack (ttk), a general inhibitor of photoreceptor differentiation.  Required to block the S phase entry in the peripheral nervous system and central nervous system in a process that does not involve the degradation of ttk.  Involved in cone cell development by preventing the transcriptional repression mediated by Su(H) on Dl, probably by participating in a E3 complex that contains sno and mediates the ubiquitination and subsequent proteasomal degradation of some component of the Su(H) repressor complex.
What are the official names of this protein?
F-box-like/WD repeat-containing protein ebi.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EBI family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y377_CLOP1
Sequence: MNDNKKLGVIALAGVVISAMLGGGVYNLPQNMAQSASAGAILISWIITGIGIWFIANTFRILAAARPDATTGIYTYGELGFGKFTGFLMAWGYWICNSFANVGYAVLLMDSLNYFFPPYFKGGNNWLSIACGSLVLWIIFFIVLAGVKQASALNVIGTIGKLLPLAIFLLVLLFSFRFSTFFTDFWGLKTVAKVHDTNLGGILPQVKSTMLVTLWVFTGIEGAVVVSGRAKSQKDVSKATFLGFITCLLIYTLLSLLPLGVYSQGEISKMAPPSTAAVLMDLIGNWGSVIMNLGVIIAILSSWLIWTVMLSELPFAAAQSGTFPKIFAKENKNESPSFSLLASTIIMQIILILVHFAGNAWNMMLSITSVMALPCYLVSTLYLFKITYKNENYPTDIFAKRKYAMITAILGSIYGVWLIYAAGINYMLIAIVIYALGIPVFIKARRETSPNEKEFTKVERYFAIVLIILALIGLVYLFKFM
What is the function of this protein?
Could be an amino acid transporter.
What are the official names of this protein?
Putative amino-acid transporter CPF_0377.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AP1_ARALL
Sequence: MGRGRVQLKRIENKINRQVTFSKRRAGLLKKAHEISVLCDAEVALVVFSHKGKLFEYSTDSCMEKILERYERYSYAERQLIAPESDVNTNWSMEYNRLKAKIELLERNQRHYLGEDLNAMSPKELQNLEQQLDTALKHIRTRKNQLMYESINELQRKEKAIQEQNSMLSKQIKEREKILRAQQEQWDQQNHGHNMPPPPPPQQHQIQHPYMLSHQPSPFLNMGGLYQEEDPMAMRRNELELTLEPVYNCNLGCFAA
What is the function of this protein?
Transcription factor that promotes early floral meristem identity in synergy with LEAFY.  Displays a redundant function with CAULIFLOWER in the up-regulation of LEAFY.  Required subsequently for the transition of an inflorescence meristem into a floral meristem, and for the normal development of sepals and petals in flowers.  Regulates positively B class homeotic proteins (By similarity).
What are the official names of this protein?
Floral homeotic protein APETALA 1, Agamous-like MADS-box protein AP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: TMCC2_HUMAN
Sequence: MKRCRSDELQQQQGEEDGAGLEDAASHLPGADLRPGETTGANSAGGPTSDAGAAAAPNPGPRSKPPDLKKIQQLSEGSMFGHGLKHLFHSRRRSREREHQTSQDSQQHQQQQGMSDHDSPDEKERSPEMHRVSYAMSLHDLPARPTAFNRVLQQIRSRPSIKRGASLHSSSGGGSSGSSSRRTKSSSLEPQRGSPHLLRKAPQDSSLAAILHQHQCRPRSSSTTDTALLLADGSNVYLLAEEAEGIGDKVDKGDLVALSLPAGHGDTDGPISLDVPDGAPDPQRTKAAIDHLHQKILKITEQIKIEQEARDDNVAEYLKLANNADKQQVSRIKQVFEKKNQKSAQTIAQLHKKLEHYRRRLKEIEQNGPSRQPKDVLRDMQQGLKDVGANVRAGISGFGGGVVEGVKGSLSGLSQATHTAVVSKPREFASLIRNKFGSADNIAHLKDPLEDGPPEEAARALSGSATLVSSPKYGSDDECSSASASSAGAGSNSGAGPGGALGSPKSNALYGAPGNLDALLEELREIKEGQSHLEDSMEDLKTQLQRDYTYMTQCLQEERYRYERLEEQLNDLTELHQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRVTKLELQQQQQQVVQLEGVENANARALLGKFINVILALMAVLLVFVSTIANFITPLMKTRLRITSTTLLVLVLFLLWKHWDSLTYLLEHVLLPS
What is the function of this protein?
May be involved in the regulation of the proteolytic processing of the amyloid precursor protein (APP) possibly also implicating APOE.
What are the official names of this protein?
Transmembrane and coiled-coil domains protein 2, Cerebral protein 11.
What is the protein family that this protein belongs to?
Belongs to the TEX28 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Concentrates in discrete patches along peripheral endoplasmic reticulum tubules.