PharMolix/UniProtQA huggingface dataset:
Protein: PANC_HERA2
Sequence: MQVVTTIEEVRAARRQWAEVGFVPTMGFLHAGHLSLVQQSKAENGVAIASIFVNPTQFGPNEDFASYPRDTPRDLALLEAAGCDLVWMPSVEEIYPAGFSSYVEVEGVTAPLEGARRPGHFRGVATVVTKLFNVVQPTKAYFGQKDAQQTVVIRQFVRDLAMPVEVVIAPTIREADGLAMSSRNSYLNAEQRAAAPVLYRALTAAQTAYAAGQTDAEAIRQLMLETLAQEPLAQVDYVSIADPRSLQELTTIDQQGVLVSLAVRIGKTRLIDNLVM
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIPI_SCHPO
Sequence: MSNQVIVTNISPEVTEKQISDFFSFCGKVSNISTEKSGETQTAKIQFERPSATKTALLLQDALLGQNKIQITSEDGGAASTTDQGGAGGDQAARQEDKPRSAIISELLSRGYHLSDVTLEKSIQLDQSYGVSSKFKGILESALSGVRSVNERYHVTEKANEVDNKFAISDKLNRTSSLVSTYFHKALETAAGTSAGQKVQNAYEDGKNQLLGIHNEARRLADAKNQAEGTASPASSTPTAPAEKEPTAPTTESKTTE
What are the official names of this protein?
Protein vip1.
Protein: DRS34_PHYTB
Sequence: GLFKTLIKGAGKMLGHVAKEFLGSEGEPES
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Dermaseptin-3.4TR.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: U119A_BOVIN
Sequence: MKVKKGGGGAGTGAEHAPGASGPNVEPKPELQAESESGSESEPEAGPGPRPGPLQRKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPPASERLPINPRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPALSEELINEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP
What is the function of this protein?
Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins.  Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization.  Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons.  Probably plays a role in trafficking proteins in photoreceptor cells.  Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A (By similarity).
What are the official names of this protein?
Protein unc-119 homolog A.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=ocalizes to the centrosome in interphase cells and begins to translocate from the spindle pole to the spindle midzone after the onset of mitosis; it then localizes to the intercellular bridge in telophase cells and to the midbody in cytokinetic cells.
Protein: LPXC_ECO55
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSAVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: GSA_BURA4
Sequence: MSNNQILFERAQKTIPGGVNSPVRAFRSVGGTPRFVSRAQGPYFWDADGKQYIDYIGSWGPMIVGHVHPEVLSAVQKVLADGFSFGAPTEAEIEIAEEICKLVPSIEQVRMVSSGTEATMSALRLARGFTGRSRIVKFEGCYHGHADSLLVKAGSGLLTFGNPTSAGVPADIAKHTTVLEYNNVAALEEAFGAFGDEIAAVIVEPVAGNMNLVRGTPEFLNALRALCTKHGAVLIFDEVMCGFRVALGGAQQHYGITADLTCLGKVIGGGMPAAAFGGRRDIMAHLAPLGGVYQAGTLSGNPIAVAAGLKTLQLIQAPGFYDALTAQTKRLADGLAAEARAAGVPFAADSIGAMFGLYFAERVPTSFAEVTKSDTERFNRFFHLMLDEGVYFAPSAYEAGFVSSTHDDAVIDATLAAARRAFAALAA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U119B_DANRE
Sequence: MNSQSSRNETAATAVNGSDSAAASRDHKSGGGVLKRLKSRRNQVDRRPVTEEELRALGRDITPDEVLGLRAVARDYLCKLEDNIYNIDFTRFKIRDLETGTVLFEIAKPPHCDLDEEDDENRDADTSAGRFVRYQFTPAFLKLRTVGATVEFTVGDQPVTNFRMIERHYFQDRLLKSFDFDFGFCIPNSRNTCEHIYEFPQLPEDLIRLMIEHPYETRSDSFYFVDNKLIMHNKADYAYNGGQ
What is the function of this protein?
Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization.  Plays a key role in localization of proteins to the primary cilium membrane.
What are the official names of this protein?
Protein unc-119 homolog B, Protein unc-119 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: RHAT_SALEP
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKQVKQWSWETMWSVGGIVSWLILPWAISALLLPDFWAYYGQFNLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLIHTEGGRMTLLGVFVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLLLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGALVNLGFCFIRLAKVQNLSIKADFSLARPLIISNILLSALGGLMWYLQFFFYAWGHARIPAQYDYMSWMLHMSFYVLCGGLVGLVLKEWKNAGRRPVAVLSLGCVVIIIAANIVGLGMAS
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PANC_THEP1
Sequence: MKIIETIEEMKKFSEEMREKKKTIGFVPTMGYLHEGHLSLVRRARDENDVVVVSIFVNPTQFGPNEDYERYPRDFERDRKLLEKENVDCIFHPSVEEMYPPDFSTYVEETKLSKHLCGRSRPGHFRGVCTVVTKLFNIVKPHRAYFGQKDAQQFRVLRRMVRDLNMDVEMIECPIVREPDGLAMSSRNVYLSPEERQQALSLYQSLKIAENLYLNGERDAEKIKEEMIKHLSRFDKVKIDYVEIVDEETLEPVEKIDRKVIVAVAAWVGNARLIDNTILG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGACB_DANRE
Sequence: MPLVFVYGTLKKGQPNYFRLIDSSNGQAEFITCARTVEPYPLVITGECNIPFLLNVPGSGQRVYGEIYSVDQKMLEFLDWFEECPDWYQRTLIQLEILKGNGETEVEEAFVYTKTKYEPDWLNKPTYDSYDSNGDHGLKYAYEEDMTRSTLDQKSADFSQNSEQEIKKNNSLQILTSTGDDHDVNFRGPLQ
What is the function of this protein?
May contribute to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue.  Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.
What are the official names of this protein?
Gamma-glutamylaminecyclotransferase B, GGACT B, AIG2-like domain-containing protein 1-B, Gamma-glutamylamine cyclotransferase B, Gamma-glutamylamine cyclotransferase, tandem duplicate 2.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family.
Protein: A1IA2_LOXHI
Sequence: ALMGHMVNAIYQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENYNDFLKGLRSATTPGNSKYQSKLILVVFDLKTGSLYDNQASEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFTDTLKQEGHPELLEKVGYDFSGNDAVGDVAKAYKKAGVSGHVWQSDGITNCLLRGPTRVKEAVANRDSGNGYINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVIADVMNEAAYKNKVRLATYEDSPWVTFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LhSicTox-alphaIA2aii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP_PROM3
Sequence: MISSNDFRTGTSIELDGSVWRVVEFLHVKPGKGSAFVRTKLKAVQSGSVVEKTFRAGEMLPQALLEKSTLQHTYMESGDYVFMDMSSYEETRLTAQQIGDSRKYLKEGMEVNVVSWNGNPLEVELPNSVVLEITETDPGVKGDTATGGTKPAILETGAQVMVPLFLSVGEKIKVDTRNDSYLGREN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOU_STRR6
Sequence: MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAELIINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAKAVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYYALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN
What is the function of this protein?
Plays a role in the regulation of phosphate uptake.
What are the official names of this protein?
Phosphate-specific transport system accessory protein PhoU homolog, Pst system accessory protein PhoU homolog.
What is the protein family that this protein belongs to?
Belongs to the PhoU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIMC_ECOL6
Sequence: MSNKNVNVRKSQEITFCLLAGILMFMAMVVAGRAEAGVALGATRVIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVKDGRFIVTPPLFAMKGKKENTLRILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPPDQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGTRVLENALVPPMGESAVKLPSDAGSNITYRTINDYGALTPKMTGVME
What is the function of this protein?
Required for the biogenesis of type 1 fimbriae.  Binds and interact with FimH (By similarity).
What are the official names of this protein?
Chaperone protein FimC.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SPT6_ASPFU
Sequence: MSARDFVEGEAVLDDEENENEEEQEEDYDGEVHEGAGTMNHYNDSSEEEEEDDDDEEAARAIREGFIVDEDEEIEERAERRREKRKRRREEREREDEHLDEEDLELIGELNPAFQSAAATESKFKRLKRGHKDHRQASQGIDDIFNSDEDEEAAGDYGRPSHRRPMHDEMKDFIEEDVFTDDELEREREDLEIARPAKRGVTGLGATDAAGLDENALEDMRAAFGDGNEYLFALEMEEQEEEQEEDQEKHLDLKDVFEPSQLAERMLTEEDNQIRLLDEPERHQLARKPYRNLVLTEEQFREEAAWIANLMLLKKRIEPELREPFQRSVAKVLEFLVTDDWEVPFIFQHRKDYMIHATKVPVAGAPADGDTSQYTIKAEKLLNMTDLWDIFDHDLKFRALVEKRNTIQKTYDNLQSLFNVNDSVVQDMLSTAVTMEELQDVQDYVHFQYASQLRDINLMNGEANGDTHRRKATGRSFFERVRNGKAYGLVRAFGITADAFAQNALKEGRRQYTEDPAERPEEMADSFIDNDFSNASHVLKAAKALFAEEIVMSPKMRKVIRQAYYMNGAVDCFRTEKGLRRIDEQHPYYEFKYLRNQQLSDIARQPELYLRMLKAEEEGLVEVKVRFENFDHFRQRLYPDIESDNYSEIADAWNRTRREVLDMALGKLERLINRSVKENIRQECENHVAKECREAFSQRLDQAPYKPKGMVLGTVPRVLAMSTGTGIVGRDPIHWAYVEEDGRVLENGKFVDLSIGDRDRSIPDGKDVEALIELLERRRPDVIGVSGMSPETRKLYKLLTELVEKKDLRGATYTDERDEEISDPLEVVIVNDEVARLYQHSERAKKDHPSFGPLTHYCVALAKYLQSPLKEYASLGRDIVSIQFKRGQQLVAQELLLKQLETALVDMVNLVGVDINEAVTDPATANLLPYVCGLGPRKAAHLLKIVNMNGGVVNNRVELLGVNAQYPAMGVKVWNNCASFLFIDFENADPDADPLDNTRVHPEDYDIARKMAADALELDEEDIKAETDENGPGAIVRKLFRDEAQDRVNDLILEEYAEQLEKNLNQRKRATLETIRAELQQPYEELRKQFALLSTDDVFTMLTGETSDTLAEGMVVPISIKRITDDHIDGKLDCGVDVLVPESELTDRYDIPVRALYSLHQTLPAKVLFLNKKNFLCNVSLREEQVSRPTPRPRDHMRGEWDDRQEAKDREMLQEKTQSGGRVMRVIKHPLFRPFNSTQAEEFLGSQSRGDVVIRPSSKGPDHLAVTWKVADGIFQHIDVLELDKENEFSVGRTLKVGGRYTYSDLDDLIFNHVKAMAKKVDEMMLHEKYQEGSKDATYSWLNTYTKANPRRSAYAFCIDPKHPGYFQLCFKAGENAQLHSWPVKVIPQGYELQRNPYPDMRALCNGFKLLFTNMQAGKR
What is the function of this protein?
Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters.  Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).
What are the official names of this protein?
Transcription elongation factor spt6, Chromatin elongation factor spt6.
What is the protein family that this protein belongs to?
Belongs to the SPT6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDUI_BACP2
Sequence: MENRYAVHPEQVKRFTTEELRRHFHIPTLFVSGELKLYYSHEDRVVIGGVMPSAEPLKLDAGDFLRTEYFLERREIGIVNVGGQGTVTVDGEAFVLEHKDFLYIGLGHEDVQFASASGEEAKFYLVSATAHQAYPTQKAAIAELTPNHLGEASASNVRNLYQVIHANGIQSCQLMMGITQLETNNTWNTMPAHIHDRRMEVYLYLDIEEDARVFHFMGEPSETRHLVLANEEAVISPAWSIHSGSGTANYSFIWAMAGENYTFKDMDFVPMDQLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: GCSH_BACMK
Sequence: MSIPNNLRYSEEHEWVKTEGNAVVIGITHFAQGELGDIVFVELPEVGATIQADEPFGSVESVKTVSELYAPVSGKVVAVNEELSDQPELVNESPYEGAWMVKVELSDASQVEKLLTAEKYAEMTNQD
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: Y1354_METJA
Sequence: MDVGIILGILSAMGFLVFLGIGGHILIGYEIIRKISKAYEKGEDVKELENKIINKSHLTNTLEKITTFTLTSIFLFEMEKYRYVIDVGYSILFLVTLTLYLVPNLSLLVWVTFFGATVFMIMLWILRFRAIKEFNKAFIEELTTQ
What are the official names of this protein?
Uncharacterized protein MJ1354.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPO4_YERPN
Sequence: MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLRKSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQEHTWPVLNKVDLLEIAHAAWHERRAERGVRLVGLHVTLLDPQLERQLLLDWG
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C209A_MOUSE
Sequence: MSDSKEMGKRQLRPLDEELLTSSHTRHSIKGFGFQTNSGFSSFTGCLVHSQVPLALQVLFLAVCSVLLVVILVKVYKIPSSQEENNQMNVYQELTQLKAGVDRLCRSCPWDWTHFQGSCYFFSVAQKSWNDSATACHNVGAQLVVIKSDEEQNFLQQTSKKRGYTWMGLIDMSKESTWYWVDGSPLTLSFMKYWSKGEPNNLGEEDCAEFRDDGWNDTKCTNKKFWICKKLSTSCPSK
What is the function of this protein?
Probable pathogen-recognition receptor.  May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments.  May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens.
What are the official names of this protein?
CD209 antigen-like protein A, Dendritic cell-specific ICAM-3-grabbing non-integrin, DC-SIGN.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: ISPG_PSECP
Sequence: MTSVSLGMPAAPPPVLAPRRKTRQIKVGSVGVGSDSPISVQSMTTTPTTDINATLQQIAELTASGCDIVRVACPSADDAEALPIIARKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNIRKFDDQVKEIAAAARDHGTSIRIGVNAGSLEPGILKKYGKATPEALVESAVWEASLFEEHGFHDFKISVKHNDPVIMVAAYEMLAEKGDWPLHLGVTEAGPAFQGTIKSATAFGALLSRGIGDTIRVSLSAPPVEEIKVGNQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAEQVTAGLEGMEIPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESQIVETLIEEAMRIAEEMGEADGEDAVKGGPVVSVS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: TRPD_METM6
Sequence: MLNKIIERENLSFEESYELFNMLLNESEMRIAAYLVALQTKGVTADEIAGFAKAMRDNAVKIDLGEVTDTCGTGGDGSKTINVSTAVSIILSCFTKVAKHGNVSITSKSGSANVYEALGCKIPETPDDAKKSMEKTNFAFLFAPKYHPTLKKIMPVRNELKVKTIFNILGPLANPANPKYQILGVNSAELSENVAIALSKVGGIKKALVVYGNGLDELTPNGTSKITEYDGKFDTYEVTPKDFGLDYSKIRPCESPDESAKRLIDVFSGKINDDRNFILMNAAGALYTSEIASDFLDGVEIAKEAIESGKVLKKLEEIRNV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RL30_CLOK1
Sequence: MAKLKITLKKSLIGRKKDHIATVNALGLKKIGKVVEHEDNPQIKGMIKKVSYLLEVEEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: LSR2_MYCTU
Sequence: MAKKVTVTLVDDFDGSGAADETVEFGLDGVTYEIDLSTKNATKLRGDLKQWVAAGRRVGGRRRGRSGSGRGRGAIDREQSAAIREWARRNGHNVSTRGRIPADVIDAYHAAT
What is the function of this protein?
DNA-bridging protein that has both architectural and regulatory roles (PubMed:18187505).  Influences the organization of chromatin and gene expression by binding non-specifically to DNA, with a preference for AT-rich sequences, and bridging distant DNA segments (PubMed:20133735).  Binds in the minor groove of AT-rich DNA (PubMed:21673140).  Represses expression of multiple genes involved in a broad range of cellular processes, including major virulence factors or antibiotic-induced genes, such as iniBAC or efpA (PubMed:17590082), and genes important for adaptation of changing O(2) levels (PubMed:24895305).  May also activate expression of some gene (PubMed:24895305).  May coordinate global gene regulation and virulence (PubMed:20133735).  Also protects mycobacteria against reactive oxygen intermediates during macrophage infection by acting as a physical barrier to DNA degradation (PubMed:19237572); the physical protection has been questioned (PubMed:24895305).  A strain overexpressing this protein consumes O(2) more slowly than wild-type (PubMed:24895305).
What are the official names of this protein?
Nucleoid-associated protein Lsr2.
What is the protein family that this protein belongs to?
Belongs to the Lsr2 family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DAPF_BACTN
Sequence: MTTKIKFTKMHGAGNDYIYVDTTRYPIAAPEKKAIEWSKFHTGIGSDGLILIGSSDKADFSMRIFNADGSEAMMCGNGSRCVGKYVYEYGLTAKKEITLDTRSGIKVLKLHVEGGKVTAVTVDMGSPLETEAVDFGDQFPFQSTRVSMGNPHLVTFVEDITQINLPEIGPQLENYHLFPDRTNVEFAQIVGKDTIRMRVWERGSGITQACGTGACATAVAAVLHGLAGRKCDIIMDGGTVTIEWEEATGHILMTGPATKVFDGEMEG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHSIC_DICD3
Sequence: MTFQTLSSENNELLTIASESFLKRWAFSEQRLTVDLMTSDDDELTVYIETDLVQSSPIYLNEDLNICRLSIQDMHEILAVQHGYYVPPSRFGDLMKYSSECYSFFYGRKSDFKYLASFIGYEKYIACPIRFLEDISWRIR
What is the function of this protein?
Putative immunity protein component of a toxin-immunity protein module, which may function as a cellular contact-dependent growth inhibition (CDI) system.  Blocks the toxic effects of expression of the C-terminus (residues 1519-1658) of cognate toxin RhsC in E. coli.
What are the official names of this protein?
Immunity protein RhsIC.
Protein: PA2B2_SISTE
Sequence: MRTFWIVAVLLVGVEGNLLQFNKMIKIMTKKNAIPSYSSYGCYCGWGGRGRPKDATDRCCFVHDCCYEKLTDCSPKTDTYSYSLKSGVIICGGNDPCKKQICECDKAAAVCFGENLSTYKKRYMFYPDFLCTDPSETC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that displays edema-inducing activities, as well as presynaptic neurotoxicity and low myotoxicity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Basic phospholipase A2 Sct-N6, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGR_YERPA
Sequence: MRNPAKQEDLIKAFKALLKEEKFSSQGEIVLALQEEGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDVDYNDSVVVINTSPGAAQLIARLLDSLGKAEGILGSIAGDDTIFTTPARGFTVKQLHEAILRLFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H14C1_CYRHA
Sequence: MKVVLIVCLVWVMAMMELVSCECWSQADCSDGHCCAGSSFSKNCRPYGGDGEQCEPRNKYEVYSTGCPCEENLMCSVINRCQSA
What are the official names of this protein?
U8-theraphotoxin-Hhn1c 1, U8-TRTX-Hhn1c 1, Hainantoxin-XIV-3, HNTX-XIV-3.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.