PharMolix/UniProtQA huggingface dataset:
Protein: RLMN_STRCO
Sequence: MPKPGELTFVAPRGVKKPPRHLADLTPAERKEAVAAIGEKPFRAKQLSQHYFARYAHAPEQWTDIPAGSREGLREALLPELMTVVRHLSTDQGTTRKTLWKLFDGTLVESVLMRYPDRVTMCISSQAGCGMNCPFCATGQAGLDRNLSTAEIVHQIVDGMRALRDGEVPGGPARLSNIVFMGMGEPLANYNRVVGAIRRLTDPEPDGLGLSQRGITVSTVGLVPAIHRFTGEGFKCRLAISLHAPDDELRDTLVPVNTRWKVREVLDAGFEYAAKSGRRLSIEYALIRDINDQAWRGDRLGRLLRGRPVHVNLIPLNPTPGSKWTASRPEDEKAFVEAIAAHGVPVTIRDTRGQEIDGACGQLAASER
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFGM_CRYNJ
Sequence: MSAIARAAARVRQQNTTPLQRPLLLQRKPVLTHTLALHASPLKPSLATSITSPNFQQSFQRRWASASATAEEGAKEEVWPQRKLPELTETDKLRLRRQRNVGISAHIDSGKTTLTERVLYYTGRIRDIHEVRGRDAVGAKMDSMELEREKGITIQSAATFADWVAPKPPTELKEGETVGNTDKQKFAINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVSGVQSQTITVDRQMRRYNVPRLAFINKMDRAGSNPFRVIGQLRGKLKMNAAAVQVPIGSESDFAGVVDIVRMKAIYNEGVKGNQIVETDEIPESVRALAEEKRAELIEQLSEADETLCDLFLDEAPITPTDIAQALQRATTSLRFTPVFMGSAIKNTGVQPLLDGVCAYLPNPSEVQNQAMDATLPAHAPTIPLVPATDAPLVGLAFKLEEGRYGQLTYMRVYQGELKRGSMIYNARTGKRVKVPRLVRMHADEMEDVDAVVAGEICAMFGVECSSGDTFTDGSSTYTMTSMFVPEPVISLSIRPEGNETPNFSRALNRFQKEDPTFRVHVDSESQETIISGMGELHLDIYVERMKREYNVACVTGKPRVAFRETITEAAKFNYTHKKQSGGSGQFGRVIGSIEPMETDPDTGKDTAFENRIIGGNIPNQFIPAIQKGFQEALDRGLITGHPITGCKFVLDDGSAHAVDSNELAFRLAAIGAFREAFNKARPVVLEPVMTVEIVAPIEFQGNVIGAINQRKGTIVDTEVRDDEFTLTAEVALNDMFGYSSQLRGMTQGKGEFSMEYKNHQPVLPNIQKEMAEAFRKKQLSK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RECA_ROSS1
Sequence: MALSPEKEKALAAAMSQIDRKYGKGSIMRMGEVSSKLAIEVIPTGSIALDIALGVGGVPRGRVVEIYGPESSGKTTLAQHIIAEAQKMGGIAAFIDAEHAFDPVYAARCGVDVNNLLVSQPDYGEQALEICEALVRSNAVDVVVVDSVAALVPRAEIEGDMGDSLPGLQARLMSQALRKLSGAISKSRAVVIFLNQLRLKIGVMFGSPETTTGGQALKFYASVRMDIRRIETLKNGQETIGSRTRVKVVKNKVAPPFRQAEFDIMHNEGISRAGNILDVGVELDIIRKSGAWFYLGDDRLGQGRENAKQFLNENPALADEIERLIRAHAMAAPISIVSPKEDDAVEDAGLFEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_PORGI
Sequence: MAQHVKKPEWLKIRLGGNEKFTETKSIVEGHCLHTICTSGKCPNMGECWSRGTATFMIGGDICTRACRFCNTLTGRPKPLNEAEPTHVALSIKLMGLNHAVVTSVDRDDLPDYGAAHWVKTIQEIRRINSGVTLEVLIPDFKGRMDLVDMIIEASPDVISHNLETVRRLTPSVRSVATYDTSLAVLRHIAQSGKMPAKTGMMLGLGETEEEILELMDDALAAGVSVITIGQYLQPSRKNLPVVEYITPEQFEHLRLVGIEKGFRTIESAPLVRSSYHAERHL
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETA_STAA3
Sequence: MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPATNPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGVTYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEGAIEVKPYAK
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: RAB6B_HUMAN
Sequence: MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQRAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGGCSC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between active GTP-bound and inactive GDP-bound states.  In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology (Probable).  Recruits VPS13B to the Golgi membrane (PubMed:25492866).  Regulates the compacted morphology of the Golgi (PubMed:26209634).  Seems to have a role in retrograde membrane traffic at the level of the Golgi complex.  May function in retrograde transport in neuronal cells (PubMed:17707369).  Plays a role in neuron projection development (PubMed:25492866).
What are the official names of this protein?
Ras-related protein Rab-6B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid- anchor. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle. Note=Colocalizes with BICD1 at vesicular structures that align along microtubules.
Protein: 3SA1_NAJHA
Sequence: LKCHKLVPPVWKTCPEGKNLCYKMFMVSTSTVPVKRGCIDVCPKNSALVKYVCCSTDKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 1, Toxin V(II)1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: Y1491_MYCTA
Sequence: MTLPLLGPMTLSGFAHSWFFLFLFVVAGLVALYILMQLARQRRMLRFANMELLESVAPKRPSRWRHVPAILLVLSLLLFTIAMAGPTHDVRIPRNRAVVMLVIDVSQSMRATDVEPSRMVAAQEAAKQFADELTPGINLGLIAYAGTATVLVSPTTNREATKNALDKLQFADRTATGEAIFTALQAIATVGAVIGGGDTPPPARIVLFSDGKETMPTNPDNPKGAYTAARTAKDQGVPISTISFGTPYGFVEINDQRQPVPVDDETMKKVAQLSGGNSYNAATLAELRAVYSSLQQQIGYETIKGDASVGWLRLGALALALAALAALLINRRLPT
What are the official names of this protein?
UPF0353 protein MRA_1491.
What is the protein family that this protein belongs to?
Belongs to the UPF0353 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURNU_SYNY3
Sequence: MTMGDDLWGWQNINGSPYLTCALLAPWPHAFFTRAFYPQLPEQLITYLDPQGKAFRVKQVHGDVTLTATEIGQTPLAPDSTHPPADGIISDAPHQGVWVASADCTPVLIGDLIGKRVAAIHAGWRGTKARIVPKTIDKFLALGSELKDLRVALGPAIAGEVYQVDPWVALEVGQSVQAVQKLATEEQQWDHLSTMVNPPVLPDAEPEKYRLDVRRINQLQLLELGFAQEQIAVAPHCTFQMEELFFSYRRTHTKEVQWSGIVSY
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase slr1573, Adenosine deaminase slr1573, S-methyl-5'-thioadenosine phosphorylase slr1573.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: RIBBA_AQUAE
Sequence: MSEREEFKFNTVEEAIEDIRQGKMVIVVDDPDRENEGDLVMAAEKVTPEAINFMAKYGRGLICLSLTPERCEQLDLHPMTPMNTDPKGTYFCVSIDAHPKHGTTTGISAYDRALTIKLAISPDAKPSDFVRPGHVFPLKARPGGVLERAGHTEASVDLARLAGLYPAGVICEIMKDDGTMARVPDLMEFAKKHNLKIITIADLIKYRLRRETLVEKVASAHLPTPWGVFKIHAYRHKLTGEEQVALTMGEWKEDEPVLVRVHSECLTGDVFRSFRCDCRPQLEKALEMIAKEGKGVLVYILGHEGRGIGIANKIKAYELQEKGYDTVEANEKLGYPPDLRDYGIGAQILRDLGVRKMKLMTNNPRKIVALEGFGLEVVERVPIKIEPNPYNKIYLQVKKDKLGHMF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: TRMB_HAEDU
Sequence: MSEKYTFADQKRKTVEQAEFTEDGRYLRKVRSFVLRTGRLSDFQRDMMNDHWAKFGLDYQKSPFDFVEIFGNANPVVLEIGFGMGRSLVEMAAQNPDRNYIGIEVHTPGVGACIAYAVEKQVDNLRVICHDATEILRDAVADGSLAGLQLYFPDPWQKSKHHKRRIVQTEFVMRLLTKLTAGGFIHFATDWQNYAEHMLAVLRQFSPALVNTSPTGDFIDRPAFRPLTKFEARGQRLGHAVWDLYFVKK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: USPB_ECO7I
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: K1C18_MOUSE
Sequence: MSFTTRSTTFSTNYRSLGSVRTPSQRVRPASSAASVYAGAGGSGSRISVSRSVWGGSVGSAGLAGMGGIQTEKETMQDLNDRLASYLDKVKSLETENRRLESKIREHLEKKGPQGVRDWGHYFKIIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVVDDTNITRLQLETEIEALKEELLFMKKNHEEEVQGLEAQIASSGLTVEVDAPKSQDLSKIMADIRAQYEALAQKNREELDKYWSQQIEESTTVVTTKSAEIRDAETTLTELRRTLQTLEIDLDSMKNQNINLENSLGDVEARYKAQMEQLNGVLLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFSLNDALDSSNSMQTVQKTTTRKIVDGRVVSETNDTRVLRH
What is the function of this protein?
When phosphorylated, plays a role in filament reorganization.  Involved in the delivery of mutated CFTR to the plasma membrane.  Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity).  Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
What are the official names of this protein?
Keratin, type I cytoskeletal 18, Cytokeratin endo B, Keratin D, Cytokeratin-18, CK-18, Keratin-18, K18.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, perinuclear region. Nucleus, nucleolus. Cytoplasm.
Protein: KDSA_BRASO
Sequence: MNAPISAAPVVTAGSVRFGNQLPLAVIAGPCQLESRGHALEVASALKEIATRLNISLVYKTSFDKANRTSGSAARGLGLAQSLPIFAEIRSSLGLPVLTDVHDASQCAEVAQAVDILQIPAFLCRQTDLLLAAAATGKVVNVKKGQFLAPWDMANVVAKITGAGNPNVLATERGVSFGYNTLISDMRSLPIMAKTTGAPVIFDATHSVQQPGGQGTSSGGQREFVPVLARAAVAVGVAGVFIETHPDPDHAPSDGPNMVPLAQFEGLLRTLMAFDALAKGQAADAIR
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_SALAR
Sequence: MSHPALTQLRALRYFDAIPALEPHLRDWLLLEDSMTKRFEQQGKRVSVTLIREAFVGQSEVEEASGLLPSEARYWLREILLCADGEPWLAGRTVVPESTLCGPEQVLQHLGRTPLGRYLFTSSTLTRDFIEIGRDATLWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPC7_MYCBO
Sequence: MIVDTSVWIAYLSTSESLASRWLADRIAADSTVIVPEVVMMELLIGKTDEDTAALRRRLLQRFAIEPLAPVRDAEDAAAIHRRCRRGGDTVRSLIDCQVAAMALRIGVAVAHRDRDYEAIRTHCGLRTEPLF
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.
What are the official names of this protein?
VapC ribonuclease Mb2033, RNase Mb2033, Toxin Mb2033.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: TRMFO_LACLA
Sequence: MKKTHINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKQTPQHKTDKFAELVCSNSLRGAAITNAVGLLKEEMRRLDSVIIKAAEVTQVPAGGALAVDREGFSDFVTREVSNHPLVEVIREEITDLPEDEITIIATGPLTSDKLAEKIHEFNGADGFYFYDAAAPIIDANSINFDKVYKKSRYDKGEADYINCPMTKEEFQAFQEALISAEEAPLNSFEDLKVFEGCMPIEEMAKRGYKTMLFGPMKPVGLEYPEDYKGPRDGDFKTPYAVVQLRQDNASASLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQSRKQENLFFAGQMTGVEGYVESAASGLVAGINAVKLFNDEEVVIFPKTTAIGSLPYYITHTDSKHFQPMNVTFGIVEELEGPRIRDKKERYTKVAERALNSLTDIISKDNL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_STAA1
Sequence: MNTLNLDIVTPNGSVYNRDNVELVVMQTTAGEIGVMSGHIPTVAALKTGFVKVKFHDGTEYIAVSDGFVEVRKDKVSIIVQTAETAREIDVERAKLAKARAESHLENDDDNTDIHRAERALERANNRLRVAELK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LDHA_GOBGI
Sequence: MSTKEKLISHVMKEEPVGSRNKVTVVGVGMVGMASAISILLKDLCDELAMVDVMEDKLKGEVMDLQHGSLFLKTKIVGDKDYSVTANSKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVAWKLSGFPRHRVIGSGTNLDSARFRHLIGEKLHLHPSSCHAWIVGEHGDSSVPVWSGVNVAGVSLQGLNPQMGTEGDGEDWKAIHKEVVDGAYEVIKLKGYTSWAIGMSVADLVESIIKNMHKVHPVSTLVQGMHGVKDEVFLSVPCVLGNSGLTDVIHMTLKAEEEKQVQKSAETLWGVQKELIL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPS_METTH
Sequence: MSPLKPLYKLYEWYISRNLRRDRMPRHVAIIMDGNRRYSKLQGSMNPIEGHKKGIETLEKVLDWCVDLGIEIVTAYAFSTENFKRPEKEVKGLMKLFRENFEAIASNEKIHKNRVRVRAVGKLELLPEDVRRAIEIAEKSTEQYSDRLVNIAIGYDGRQEIVDATRKIAEDVKAGLIDPEDIDEDMINRNLYTAGLEDPHLIIRTSGEERLSGFLLWQSSYSELYFCDSLWPELRKVDFLRAIRSYQQRERRFGV
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP).  It is probably the precursor of glycosyl carrier lipids.
What are the official names of this protein?
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific), Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: NIM1_HUMAN
Sequence: MTAVYMNGGGLVNPHYARWDRRDSVESGCQTESSKEGEEGQPRQLTPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPKERDLKKGSRVYRGIRHTSKFCSIL
What are the official names of this protein?
Serine/threonine-protein kinase NIM1, NIM1 serine/threonine-protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: HSLU_GEOSW
Sequence: MSEALTPRQIVEKLDQFIVGQKEAKKAVAIALRNRYRRSLLDEKLRDEVVPKNILMIGPTGVGKTEIARRLAKLVGAPFVKVEATKFTEVGYVGRDVESMVRDLVETSVRLVKERKMNEVKDRAEQQANKRLVELLVPGKQKQTMKNPLELLFGGAQTSQQDTYQTYEDDHIEQKRRQVAWQLANGQLEDEMVTIEVEEQQPMFFDFLQGAGIEQMGMNMQDALSSLIPKRRKKRKLKVREARKVLTNEEAQKLIDMDEVTQEAIRLAEQSGIIFIDEIDKIARSGQAASSADVSREGVQRDILPIVEGSTVMTKYGPVKTDHILFIAAGAFHMAKPSDLIPELQGRFPIRVELTKLSVDDFVKILVEPDNALIKQYKALLATEGINLEFSDDAIRKIAEVAFEVNQTTDNIGARRLHTIMEKLLEDLLFEAPDITLDEVVITPQYVEQKLGNIVKNKDLSEFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSTX3_PARSR
Sequence: DCLGWFKGCDPDNDKCCEGYKCNRRDKWCKYKLW
What is the function of this protein?
Potent voltage-gated sodium channel blocker (IC(50)=190 nM and 210 nM on human and rat Nav1. 3/SCN3A respectively, 430 nM on human Nav1. 7/SCN9A, 770 nM and 290 nM on human and rat Nav1. 8/SCN10A respectively) (PubMed:24211312).  Binds the voltage-sensor domain of the potassium channel KvAP (from Aeropyrum pernix) and weakly inhibits this channel (By similarity).
What are the official names of this protein?
Voltage sensor toxin 3, VSTX3, Beta/kappa-theraphotoxin-Gr4a, Beta/kappa-TRTX-Gr4a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 61 (VSTX3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: H2A05_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEEFEAESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Neurotoxin active on both insects and mammals.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II.5, HNTX-II.5, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MDH_BRUC2
Sequence: MARNKIALIGSGMIGGTLAHLAGLKELGDVVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTGANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLDAMVWALQKFSGLPAHKVVGMAGVLDSARFRYFLSEEFNVSVEDVTAFVLGGHGDSMVPLARYSTVAGIPLPDLVKMGWTSRDKLDKIIQRTRDGGAEIVGLLKTGSAFYAPAASAIQVAESYLKDKKRVLPVAAQLSGQYGVKDMYVGVPTVIGANGVERIIEIDLDKDEKAQFDKSVASVAGLCEACIGIAPSLK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: IF2_BDEBA
Sequence: MSNPKVFEFAKEIGMTPLALMDKIREWHLPVKSHMAELEPEVLEQIKIKLSGGEKSGDEAKPKKTAARKAAPKKAAVAAPVPEADASSAAAKTPVIRRKKDEVPAEAPKAKVVAKPEGEVEEAAAAPKTTRVVVKKPAVKAEAEEVEETPEVEAAAPVEEKAPVKAAVKEEAPAPVEKPEPVVAKEVPAAPVAAAPEAPAPQARKKEVVVGTSGVSSSATPASAPKRNIIGRMDLSRVQSQAPQRPQGERPAGGFTPRAGGEQRGASASFTGQRPGGFNRPAGGAPTRNIRTGFVAANQPPEPIVETGADRGGRDFDKRKRTFGPSAPAAGPAAAGRGAGEKEEVVVSFNAVEFRKREMVFQPKKKKGLLDRDAMKTQITTPSAHKRVVKVNNTMKLSDLAMEMGLKAPQLVRELMKQGVMANMNMDLDFDTIALIVPEFGWEAQNVFKTADEVAEQTAFGDLDAAPVTRPPVVTVMGHVDHGKTSLLDAIRNADVAKGEAGGITQHIGAYSVKIEDGSLITFLDTPGHEAFTAMRARGANATDIAIIVVAADDGMMPQTQEAINHAKAAGVPIIVAVNKIDKPGANPERIKQQLTELEIVPEEWGGSTIFCEVSALKKTGITELLEQIKLVAEVAELKANPKRSGTGLVIEAKMEKGKGPVATLLVKDGTVEVGQYIVAGTMKGRVRSLTNDRGERVQSAGPGIPVEVLGLEAVPAAGDKFDIVKDEVTATKVSELRKEQAEKAAATPAAKLSLDEVFAKVKAGDVKELAIVLKADVHGSLEAINGMLAKLSTPEVKARVIHSAVGGINEGDIVLANTAKGIVLGFNVRPDLGAQAKAKQMGVDVRTYSIVYELIDQMKAAMGGLLSPDIVEEVLGRAEVRNVFTVPKVGTIAGCFVIDGKVQRNASIRLLRENKIVYEGKIASLKRFKDDAKEVASGYECGIGIENYNDVKVGDQMEAFVKKEVARELEGGAN
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.