PharMolix/UniProtQA huggingface dataset:
Protein: ELA_HUMAN
Sequence: MRFQQFLFAFFIFIMSLLLISGQRPVNLTMRRKLRKHNCLQRRCMPLHSRVPFP
What is the function of this protein?
Endogenous ligand for the apelin receptor (APLNR) (PubMed:25639753, PubMed:28137936).  Hormone required for mesendodermal differentiation, blood vessels formation and heart morphogenesis during early development and for adult cardiovascular homeostasis (PubMed:25639753, PubMed:28137936).  Drives internalization of APLNR.  Acts as a motogen by promoting mesendodermal cell migration during gastrulation by binding and activating APLNR.  Acts as an early embryonic regulator of cellular movement with a role in migration and development of cardiac progenitor cells.  May act as a chemoattractant for the activation of angioblast migration toward the embryonic midline, i. e.  the position of the future vessel formation, during vasculogenesis.  Positively regulates sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel sprouting.  Plays a role in placental vascular development; promotes placental trophoblast invasion and spiral artery remodeling in the uterus.  Involved in the regulation of maternal cardiovascular homeostasis to prevent gestational hypertension and for potent cardioprotective functions during heart failure.  Mediates myocardial contractility in an ERK1/2-dependent manner (By similarity).
What are the official names of this protein?
Apelin receptor early endogenous ligand, Protein Elabela, ELA, Protein Toddler.
What is the protein family that this protein belongs to?
Belongs to the Elabela/Toddler family.
Protein: OBG_DELAS
Sequence: MKFVDEAYIDISAGDGGNGCVSFRHEKYKEFGGPDGGDGGRGGHVYAVADVNLNTLVDYRFSRRHDATRGEHGKGSDMFGAAGNDITLRMPVGTIISDAETGEVLYELLTAGEVVTIAKGGDGGYGNLRFKSAINRAPRQKTPGWPGERKNLKLELKVLADVGLLGMPNAGKSTFIAAVSNARPKIADYPFTTLHPNLGVVRVAAEQSFVVADIPGLIEGASEGAGLGHQFLRHLQRTRLLLHVVDLAPFDDSVDPVAQAKAIVGELQKYDAELYNKPRWLVLNKLDMVPAEERAARVKDFVKRFKWKGPVFEISALTREGCEVLIRTIYKHVHEQQQIEAGPKEIDPRFVEVEGDGVDLTDPRFAPRDSE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_ACTP7
Sequence: MAQVSMRDMLNAGVHYGHQTRYWNPKMKPFIFGARNGVHVINLEKTLPLFNEALAELTRISSNNGKILFVGTKRAASEAVKAAAVDCQQFYVNHRWLGGMLTNWKTVRQSIKRLKDLETQTQDGTFDKITKKEALMRTRELEKLELSLGGIKDMAGLPDAIFVIGADHEHIAIKEANNLGIPVFAIVDTNSTPDGVNYIIPGNDDATRAIQLYLDAAAAAVKEGRGSNVEAELEATAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: FSIP1_MOUSE
Sequence: MPMDIIKGNLDGISKPASSSRSRPGSRSSNGSLEVLTPEPGSVKIDMVNKLNSGQEGHTSNSGVEERRNSNDAKWADDSKTKPAKESSDEDPDMPQPQATPEHSDDPKLEETNAVLQNAIRKMHRLDKLLAKKQCREKEVKKQGLEMRVKLWEELKSAKNTEDLENDEELGNTKKFLCLTSESAGKAAAEALHCEFEDALFSVFHTQIPPETYENLMEKDFTCDVEKNEPLIITEKQPFSNTEAIEPRSEDSQGFIRQNAEHSQDFIKRNIELAKHSRSPVVMVEGEKKRLDELLQGLDDADSGLSSAEGDQCGWLVPGEGYTLAATESQQLAEIDIKLQELSVDSPTIFSLESQSHKGDMECDANEERNTEPTPGEKILRDRKEQRDRESRLRAIDGKLKELSEQVEECPMITPSKRNERITWRWLLAKILEPE
What are the official names of this protein?
Fibrous sheath-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the FSIP1 family.
Protein: STX8B_SCOVN
Sequence: LKVPDLPLPESYKKALELAKDDLAREIXI
What are the official names of this protein?
Scolopendra 8011.73 Da toxin.
What is the protein family that this protein belongs to?
Belongs to the scolopendra toxin 8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQFC_BACSU
Sequence: MGQRKNRMKAWLTRALEIPPDVMMDLPRITMVGRLHIYIENHRGLLLFSENEVRLMLKQGQCIISGKNFVIKAILPEEILLEGTIDVVRYVES
What are the official names of this protein?
Uncharacterized protein YqfC.
Protein: CLPB_OCEIH
Sequence: MMFGRFTERAQKVLALSQEEAVRLGHNNIGTEHILLGLVREGEGIAAKALQSLGLEVSKIQEEVEKLIGVGKQPTQSIHYTPRAKKVVELSQDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNESQAGRQGRSGQQSNASTPTLDSLARDLTVSAKEGKIDPVIGRSKEIERVIQVLSRRTKNNPVLIGEPGVGKTAVAEGLAQQIIDNEVPETLRDKRVMTLDMGTVVAGTKYRGEFEDRLKKVMEEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEYRKYIEKDAALERRFQPIQVDEPTLEETIQILNGLRDRYEAHHRVTITDEAIEAAASLSDRYITDRFLPDKAIDLIDEAGSKVRLRSYTVPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDSEQRFREELETTKNQWKEKQGQTDSEVTMEDIAAVVSTWTGVPVSKLTKDETDRLLNMEKILHDRVIGQSEAVNAVAKAIRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAEVMFADEDAMIRIDMSEYMERHATSRLVGSPPGYVGYDEGGQLTEKVRRKPYSVVLLDEVEKAHPEVFNILLQVLEDGRLTDSKGRVVDFRNTVIIMTSNVGASELKRNKYVGFALDNEEKDYKDMKSKVIEELKKAFRPEFLNRIDETIVFHSLEKEHMKDIVTLMVQQLQKRLKEQDLHLSLTDKAIEKIANEGFDPEYGARPLRRSIQKNIEDLLSEELLRGAIEKEQQVKIGLNNKGEFIVLP
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_LEPIN
Sequence: MIQELKADLNGKGQKHCVIVSRFNEFITESLLKGALESFRMHGVEDVTVVRVPGAYEMPMVVSKAAASKKYDSIVCLGAVIRGATAHFDLVAGESAKIGSIGVQHSIPVIFGVLTTDTIEQAIERAGTKAGNKGAEAAATAVEMVNLLSLL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: G6PI_PSEP1
Sequence: MAYYRTPHDVTALPAWQALQKHRDAMQSFSMREAFAADAKRFDQFSLSACGLFLDYSKNLITEQSRDLLVSLANEVGLQDAIKSMFSGEIINASEGRPVLHTALRRPVGDKLSVNGVNVMPEVHKVLNQITELVGRIHDGLWRGYSEKPITDVVNIGIGGSFLGPELVSEALLPYAQRGVRCHYLANIDGSEFHELSANLRAETTLFIVSSKSFNTLETLKNAMAARTWYLAQGGSEAELYRHFIAVSSNKAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGTANFKELLSGAYTMDQHFQTAPFDKNMPVLLALLGVWYGNFWDANSHAILPYDHYLRNITKHLQQLDMESNGKSVLQDGTPVKTDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPVVSFNPVADHHQWLYANCLSQSQALMLGKTREEAEAELRAKGLNEADIEKLAPHKVIPGNRPSNTLVVERISPRRLGALVAMYEHKVFVQSVIWGINAFDQWGVELGKELGKGVYQRLVGSLEDSAEDGSTQGLINYFRGRHRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_STRPQ
Sequence: MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIVLEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDLEEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDDLPEDAFRSVGPIEDVIKKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS18_ELUMP
Sequence: MSEEKIVNTEAAPEAVAERPARAERSERPERPAKGPFGKKRFESRRKVCKLCAEKIENVDYKNFQFIKSFTMDSGKILSRRITGTCAKHQRQIASAVKRDRNLAILPYSLPKK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: EYA_ARATH
Sequence: MNNDTSKKLGTLVSDDGPVNVYVWDMDETLILLRSLLNGTYAESFNGSKDVKRGVEIGRMWEKHILKICDDFFFYEQVEECNEPFLDSLRQYDDGKDLSRYEFKQDDFSTPTDDLNKRKLAYRHRAVAERYEKGLCPFIDSESMSGLDELYNVTDEYTDRWLSSARAFLEQCSCVEESSDGTSAIEQSSQDIHILVTSGALIPSLVKCLLFRLDTFLRHENVYSSIDVGKLQCFKWIKERFNHPKFRFCAIGDGWEECAAAQALQWPFVKIDLQPDSSHRFPGLTPKTVSYYFAAVYGNSDADSSKE
What is the function of this protein?
Possesses phosphatase activity toward para-nitrophenyl phosphate (pNPP) in vitro (PubMed:15641802).  Possesses phosphatase activity toward several phosphotyrosine-containing peptides in vitro, with low peptide substrate specificity (PubMed:18759246).
What are the official names of this protein?
Eyes absent homolog, AtEYA.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. EYA family.
Protein: DUT_NOCFA
Sequence: MSALSPIPLRRLDPGIPVPTRAHPGDAGVDLCTTEDVVLAPGERVLVGTGIAVALPVGTVGLIHPRSGLAAKTGLSVVNTPGTVDAGYRGEIKVCLINHDPRTPIELRRGDRIAQLLVQRVELVDFVEVEQLDETSRGAGGHGSSGGHASLTPGARSAARVAQEG
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PYRG_TREPA
Sequence: MDPAFIFITGGVVSSLGKGIAAGAIGLLLKSRGISVVNQKFDPYLNGDPGTMNPYQHGEVFVTQDGGETDLDLGHYERFTDVPSSRFNSTTAGSVYRAILDRERAGGYGGATVQVIPHVTDEIQARIRAAAATTGARVVITEIGGTVGDIESLPFIEAIRQIRRVLGKERCLFIHLGLVPYLPSCGEMKTKPLQHSVKELLGLGVQPDVILCRSERHITDAVREKLSLFCNVERRAIVENVTARSIYEVPLLLEAEGLGALLCERLRLFDTCCGGQVARNLGAGGAQSAVLGAGGTVRTDGGLHPAAGQGAEPDLTAWRAMVRALYYPRRELTVALVGKYVSLADAYLSVSEALTAAGICHRARVDMRWIDAEEICSVQDAGHALADADALVIPGGFGVRGIEGMICAVSHARVQNLPYLGICLGMQIAVIEFARNVLLLASAHSREFAVDTPHPVVDLLPGCVDTPTGGSLRLGQYRCLLAEGSRARALYGRGEVWERHRHRYGLNAAYRARFEASALRPVGVDSDCGAVEVVEHGEHPWFFGVQFHPEFCSRPNRAHPLFRALVAAGLERKDSRS
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: LIPB_THEP3
Sequence: MRKGEVLKLGIVPYMEGKEIQLKAFERVKKGETDGILILLQHPPVYTIGVSGGFDENILVPLAELKKKAELYKVERGGKITFHGPGQIVAYPIFNLAKWQKDVHLFVYKLEETIIKLLEEYGIKAGRKPKYTGVWVGDEKICAIGIAVRRWITWHGIAFNVNTDLSYFGLINACGITEFGVTSMQKLGINEDIEKVKEKMVDKFSEVFGIHFNEITLDRLAVIDNAKA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPA_SALSV
Sequence: MRNFDLSPLYRSAIGFDRLFNLLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIELERVIPEANKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARYLT_MYCTO
Sequence: MSASLLVRTACGGRAVAQRLRTVLWPITQTSVVAGLAWYLTHDVFNHPQAFFAPISAVVCMSATNVLRARRAQQMIVGVALGIVLGAGVHALLGSGPIAMGVVVFIALSVAVLCARGLVAQGLMFINQAAVSAVLVLVFASNGSVVFERLFDALVGGGLAIVFSILLFPPDPVVMLCSARADVLAAVRDILAELVNTVSDPTSAPPDWPMAAADRLHQQLNGLIEVRANAAMVARRAPRRWGVRSTVRDLDQQAVYLALLVSSVLHLARTIAGPGGDKLPTPVHAVLTDLAAGTGLADADPTAANEHAAAARATASTLQSAACGSNEVVRADIVQACVTDLQRVIERPGPSGMSA
What is the function of this protein?
May be involved in the import of arylamide compounds.
What are the official names of this protein?
Putative arylamide transporter.
Protein: LEPA_PSEAB
Sequence: MSDLSHIRNFSIIAHIDHGKSTLADRFIQMCGGLSDREMEAQVLDSMDLERERGITIKAHSVTLHYKAQDGKTYQLNFIDTPGHVDFTYEVSRSLAACEGALLVVDAGQGVEAQSVANCYTAIEQGLEVMPVLNKMDLPQAEPERVKEEIESIIGIDATDAVACSAKSGMGVLEVLERLVTAIPAPEGEIEAPLQALIIDSWFDNYLGVVSLVRVKNGRVKKGDKILVKSTGKVHQVDSVGVFTPKHTETVDLKAGEVGFIIAGIKDIHGAPVGDTLTLNNTPDVEVLPGFKRVKPQVYAGLFPVSSDDFEDFRDALQKLTLNDSSLQYEPESSEALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPTVVFEIVQKNGEIIYVDNPSKLPDLASIQEMREPICRATILVPKDHLGNVITLCIEKRGVQRDMHFLSGQVQVVYDLPMNEVVLDFFDRLKSTSRGYASLDYSFDRFEPSNLVRLDVLINGEKVDALALIVHRDNAPYKGRQLVEKMKELIPRQMFDVAIQAAIGGQIIARSTVKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKQVGSVEIPQEAFLAVLKVDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNH2_SALRD
Sequence: MLSHERRLWADGYERVAGLDEAGRGCLAGPVVAAAVIMPPQVEITAIQDSKALSEGQRLDARATIEDEAVAASIARCSPTEIDDRNILQAALEAMRRAASGCRPPPDFVLVDGNQWDRNLVDAPWPHETVVKGDAKSQSIAAASILAKTERDALMRDLHEAHPEYDWASNVGYPTQQHYDALREHGATPHHRQSFTLFRD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CUPPJ
Sequence: MRVAEVTRNTSETQIRVSLNLDGTGRQKLASGVPFLDHMLDQIARHGMFDLEVEATGDTHIDDHHTVEDVGITLGQAVAKAIGDKKGITRYGHSYVPLDECLSRVVIDFSGRPGLEFHVPFTRARVGSFDVDLTIEFFRGFVNHAGVTLHIDNLRGINAHHQCETVFKAFGRALRMAVELDPRAANTIPSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_PSEAB
Sequence: MTIKSDKWIRRMAQEHGMIEPFVERQVRGADDSRVISYGVSSYGYDVRCAAEFKVFTNIHSAVVDPKNFDEKSFVDINSDVCIIPPNSFALARTVEYFRIPRDVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTNLPAKIYANEGVAQMLFLQSDEACEVSYKDRGGKYQGQRGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PCNA_HALSA
Sequence: MFKAIVSADTLQETLDSVSVLVDECKIHLDDDTLSIRAVDPASVGMVDLDLAATAFESYEADGGLIGVNLSRLEDIAGMADAGQLIQLELDEETRKLHIQIDGLEYTLALIDPDSIRQEPDIPDLDLPAHVAIEGRDIDRAVTAADMVSDHIALGVDTGDDLFYVNAEGDTDDVHLELAPDQLIDLDAGDAHSLFSLDYLKDMNKAIPTTAEVELELGDEFPIKLHFDIADAQGHVTYMLAPRIQSN
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: RGS2_RAT
Sequence: MQSAMFLAVQHDCVPMDKSAGNGPKVEEKREKMKRTLLKDWKTRLSYFLQNSSTPGKPKTGKKSKQQTFIKPSPEEALLWAEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHAT
What is the function of this protein?
Regulates G protein-coupled receptor signaling cascades.  Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (By similarity).  It is involved in the negative regulation of the angiotensin-activated signaling pathway (By similarity).  Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ.  Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity).  Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 2, RGS2.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus, nucleolus.
Protein: SECB1_FRATH
Sequence: MDQQAQPQFQIQKVYVKDLSFSIPNSDKIWTTNWKPELHTDLKVEATKLPEENTYETVLTLEVKVENDGMVAFEAEVKQAGIFTVANMQEAQIEHAKKAFCPNILYHYAREAISDLVISGGFPQLCLSAVNFDAMYQDSLKESADSKQH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB 1.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_ECO81
Sequence: MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: DCAF4_HUMAN
Sequence: MNKSRWQSRRRHGRRSHQQNPWFRLRDSEDRSDSRAAQPAHDSGHGDDESPSTSSGTAGTSSVPELPGFYFDPEKKRYFRLLPGHNNCNPLTKESIRQKEMESKRLRLLQEEDRRKKIARMGFNASSMLRKSQLGFLNVTNYCHLAHELRLSCMERKKVQIRSMDPSALASDRFNLILADTNSDRLFTVNDVKVGGSKYGIINLQSLKTPTLKVFMHENLYFTNRKVNSVCWASLNHLDSHILLCLMGLAETPGCATLLPASLFVNSHPGIDRPGMLCSFRIPGAWSCAWSLNIQANNCFSTGLSRRVLLTNVVTGHRQSFGTNSDVLAQQFALMAPLLFNGCRSGEIFAIDLRCGNQGKGWKATRLFHDSAVTSVRILQDEQYLMASDMAGKIKLWDLRTTKCVRQYEGHVNEYAYLPLHVHEEEGILVAVGQDCYTRIWSLHDARLLRTIPSPYPASKADIPSVAFSSRLGGSRGAPGLLMAVGQDLYCYSYS
What is the function of this protein?
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
What are the official names of this protein?
DDB1- and CUL4-associated factor 4, WD repeat-containing protein 21A.
Protein: YQGF_FRATT
Sequence: MFQSLIAIDYGKARIGISSGQMITKTATPIGTVEAYDGVPNWIELDKIIKCWNPSDIIIGLPLDTQNFETDITKSAKDFAKEVQQRYQRKVHLINEAYSTREARWRLEEVKSKKVSHIKVDALAACVILETWMSEN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF118_ARATH
Sequence: MSKSTILAIFMIVLVLGKVTKETQGQEMCRDILMKAKNCDEGTCDTLCKQKWKGNGSCFPNVYTYRKSCLCTFPCKT
What are the official names of this protein?
Putative defensin-like protein 118, Putative low-molecular-weight cysteine-rich protein 52, Protein LCR52.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: PFKA_SHIBS
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase isozyme 1, ATP-PFK 1, Phosphofructokinase 1, 6-phosphofructokinase isozyme I, Phosphohexokinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_METFK
Sequence: MARVCQVTGKKPMVGNNVSHANNKTKRRFLPNLQNRKFWVESENRWVSLRITNAALRTIDKNGIDAVLADLRASGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ISK6_MOUSE
Sequence: MKVAGVFLLLSLALLCFFSGAFSQGGQDKRGWITRSEGRFPGKGVLRHRLFQINCGEFRDPKVFCTRESDPLCGSDGQTYGNKCAFCKALEKSSGKINLKHRGKC
What is the function of this protein?
Serine protease inhibitor selective for kallikreins.  Efficiently inhibits KLK5 and human KLK2, KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14.  Doesn't inhibit human KLK1 and KLK8.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 6.
Protein: IDI_MYCBO
Sequence: MTRSYRPAPPIERVVLLNDRGDATGVADKATVHTGDTPLHLAFSSYVSDLHDQLLITRRAATKRTWPAVWTNSCCGHPLPGESLPGAIRRRLAAELGLTPDRVDLILPGFRYRAAMADGTVENEICPVYRVQVDQQPRPNSDEVDAIRWLSWEQFVRDVTAGVIAPVSPWCRSQLG
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.