PharMolix/UniProtQA huggingface dataset:
Protein: UGO1_SCHPO
Sequence: MNPYRPYVVVNNVEPTFSITPEPTFETQPTISKSEIFETLRSILVTKYLTTFFVQPLEVAKTVCQVEEYLPKRTKIERDGKQTKEPYDEDIPDGTEQEGLSDDEHEIYAYFETPTTEKAVTEQLAEKLCVDASGYVTDPSNLIERSYTIHSKRFSIKSIISELWEKEGARGLWKGHTISFLHNLLYSGLQSWLSATLSGALAIADPNIISPIDSVRPLLSLFIKSITSAISALILSPLDIARTKIILFPISSSSYLSSASETSGNSHKKFKPLTIRQCLKALPFYCPSSLILPTVCYVSLPPFVSSVLPLTFRNFLGSSPTLDAMVGLGTSAVQFLLKCPLEMVLRRAQAQYECNLPPQTIVPVGKYTGIVGTIWCLLSEEDPGKFGIEGLYRGWRVGIWGMSSTLALNYISSNLREEVEF
What is the function of this protein?
Required for mitochondrial fusion as well as normal mitochondrial morphology.  May coordinate fusion of inner and outer membranes during mitochondrial fusion (By similarity).
What are the official names of this protein?
Mitochondrial fusion and transport protein ugo1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: BETB_PSEE4
Sequence: MARFGTQKLYIDGAYVDAGSDATFEAINPATGEVLAHVQRATQADVEKAVESAERGQKVWAAMTAMQRSRILRRAVDILRERNDELAMLETLDTGKSYSETRYVDIVTGADVLEYYAGLVPAIEGEQIPLRESSFVYTRREPLGVTVGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTTLKLAEIFTEAGLPNGVFNVLTGSGREVGTWLTEHPRIEKVSFTGGTTTGKKVMASASSSSLKEVTMELGGKSPLIICDDADLDKAADIAMMANFYSSGQVCTNGTRVFVPAAMKAAFEAKIAERVARIRAGNPEDENTNFGPLVSFQHMESVLSYIAKGKEEGARVLCGGERLTAGDFAKGAFVAPTVFTDCTDDMTIVKEEIFGPVMSILSYETEEEVIRRANDTEYGLAAGVCTNDISRAHRIIHKLEAGICWINAWGESPAEMPVGGYKQSGVGRENGVSSLAQYTRIKSVQVELGGYNSVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: HIS1_XANC5
Sequence: MSASTAAPARDRLRIAIQKSGRLAEPARSLLAACGLSWRQSRDKLFCYGESLPVDLLLVRDDDIPGLIADGVCDLGIVGQNELEEQAAERRRNGLPAAYHAVRGVGFGQCRLMLAVPEEWDWHGVGQLAGKRIATSYPAILADWLERQGIDATVVELSGSVEIAPRLGTADLICDLVSSGATLAANQLKPVELVMESEAVLAGAVREPADARAGLLAMLLRRMDGVLKLRDSKLLMFRAEQTNVDALRRLLPDADPLVQLPDDGNGALRLQTMCHGAVTWQRLEELERAGAQGLMVLTVERSLA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAB_SCHPO
Sequence: MSSKLLSMKFMQRARGIDPKQAEEELSKNIVTDEHWSLAGKVDFLPQKMTRNVEYESGYGGLIEENDLESHSNEPNLVQGRASFGLFNKELGEENVDEKDVSKNEEVDVNGTKITDTSELTERERRKQELVSKKAEASRKMEVKAPAKESKKRKVNELSQDVISLHSPKESNARKTKKNKNKKKKKRN
What are the official names of this protein?
Uncharacterized protein UNK4.11c.
What is the protein family that this protein belongs to?
Belongs to the MPP6 family.
Protein: REV1_YEAST
Sequence: MGEHGGLVDLLDSDLEYSINRETPDKNNCLSQQSVNDSHLTAKTGGLNARSFLSTLSDDSLIEYVNQLSQTNKNNSNPTAGTLRFTTKNISCDELHADLGGGEDSPIARSVIEIQESDSNGDDVKKNTVYTREAYFHEKAHGQTLQDQILKDQYKDQISSQSSKIFKNCVIYINGYTKPGRLQLHEMIVLHGGKFLHYLSSKKTVTHIVASNLPLKKRIEFANYKVVSPDWIVDSVKEARLLPWQNYSLTSKLDEQQKKLDNCKTVNSIPLPSETSLHKGSKCVGSALLPVEQQSPVNLNNLEAKRIVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNENIHKYTKITDKDTYIIFHIDFDCFFATVAYLCRSSSFSACDFKRDPIVVCHGTKNSDIASCNYVARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKRLNIFNLILPISIDEAVCVRIIPDNIHNTNTLNARLCEEIRQEIFQGTNGCTVSIGCSDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGHSTLSRLESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDEESLKILYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLNEINKTTSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFGIIATEMKSLYRTLGCPPMELRGLALQFNKLVDVGPDNNQLKLRLPFKTIVTNRAFEALPEDVKNDINNEFEKRNYKRKESGLTSNSLSSKKKGFAISRLEVNDLPSTMEEQFMNELPTQIRAEVRHDLRIQKKIQQTKLGNLQEKIKRREESLQNEKNHFMGQNSIFQPIKFQNLTRFKKICQLVKQWVAETLGDGGPHEKDVKLFVKYLIKLCDSNRVHLVLHLSNLISRELNLCAFLNQDHSGFQTWERILLNDIIPLLNRNKHTYQTVRKLDMDFEV
What is the function of this protein?
Deoxycytidyl transferase involved in DNA repair.  Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction.  May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion.  Required for normal induction of mutations by physical and chemical agents.  Involved in mitochondrial DNA mutagenesis.
What are the official names of this protein?
DNA repair protein REV1, Reversionless protein 1.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion.
Protein: PFDB_PYRAR
Sequence: MAQIPPSLQDMVNRFNQAQAQLQSVLLRKQQYEAELKEVDKAISEIEKLSPDAKIFKNVGNFLVPQTRDAALQELKERKELLELHVKTLSRQETMLREQLDKLRDEINKELARLKGGEAAKGGG
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_BACCR
Sequence: MSTMREMYPKNGRVILHVDMNCFFASVEIAHDPSLQGKPLAVAGNEKERKGIIITCSYEAREYGIRTTMPLWEAKRLCPQLVVRRPNFTLYREASFQMFQVLSRFTEKIQPVSIDEGYLDITDCYALGSPLEIAKMIQQALLTELQLPCSIGIAPNLFLAKTASDMKKPLGITVLRKRDIPEMIWPLSVEAMHGIGEKTAEKLNEIHIHTIEQLAKGDEHIIRAKIGKHGIDLQKRAKGTDDREVDPSQMGQHKSVGNSMTFSKDMDEEKELLDMLERLSKSVSKRLQKRTLVSYNIQIMIKYHDRRTVTRSKQLKNAIWEERDIFQAASRLWKQHWDGDSVRLLGVTATEIEWKTESVKQLDLFSFEEDAKKEPLLAVIDQINDKYGTPILQRGSQLLRKQEKSFQQKLENKFM
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_BRUAB
Sequence: MALYEHVLLARQDISQQQVDALVEQFKGVLEANGGKFGKVENWGLRPLTYRIKKNRKAYYTLVNIDAPAAAVAEMERQMRINEDVLRFLTVRVEEHEEGQSAMLTRRDDRRERDGDDRPRRREGGFDRGDRGDRGPRRPRDNEAGEGA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: GMHA_THIDA
Sequence: MPLHDRIVGHFQASAQSKLDAADALAPRIEQGARLLVHSLAQGGKILACGNGGSAADAQHFASEMLNRFEQERPGLAALALTTDTSTLTSIANDYAYDQVFARQVKALGQPGDVLLAISTSGNSANVLQAVAAAHARSMQVIALTGRSGGGLAEQIDDGDVCICVPAESTARIQEIHLLTIHCLCDAVDSLLLGVEE
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCRL1_HUMAN
Sequence: MLPRLLLLICAPLCEPAELFLIASPSHPTEGSPVTLTCKMPFLQSSDAQFQFCFFRDTRALGPGWSSSPKLQIAAMWKEDTGSYWCEAQTMASKVLRSRRSQINVHRVPVADVSLETQPPGGQVMEGDRLVLICSVAMGTGDITFLWYKGAVGLNLQSKTQRSLTAEYEIPSVRESDAEQYYCVAENGYGPSPSGLVSITVRIPVSRPILMLRAPRAQAAVEDVLELHCEALRGSPPILYWFYHEDITLGSRSAPSGGGASFNLSLTEEHSGNYSCEANNGLGAQRSEAVTLNFTVPTGARSNHLTSGVIEGLLSTLGPATVALLFCYGLKRKIGRRSARDPLRSLPSPLPQEFTYLNSPTPGQLQPIYENVNVVSGDEVYSLAYYNQPEQESVAAETLGTHMEDKVSLDIYSRLRKANITDVDYEDAM
What is the function of this protein?
May function as an activating coreceptor in B-cells.  May function in B-cells activation and differentiation.
What are the official names of this protein?
Fc receptor-like protein 1, FcR-like protein 1, FcRL1, Fc receptor homolog 1, FcRH1, IFGP family protein 1, hIFGP1, Immune receptor translocation-associated protein 5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TRF1_MAGO7
Sequence: MSSAAASATAGSVTGKTPRILACVLCQHRKIKCDRSFPCANCQRANVQCTPSTPAPARKRRRPNQDLQERLARCEELLKEYAPDGKPDIARLTTKRSSLSQSPPKGEEPLPEWNRHGKLIHEDGSVRFVDSYMLSTIYDELRAMRDIIDHDESTPEDESSDYMTPDTNADLLFGGDTPQPAGNSMELQPSPGHIFRLWQVFLDRVNPLIKLVHVPSLQPYFVEATAGAPLPKNIEALLFSIYTLAAVSLSDAECTSILGYGREAALHRFSSGVRASLIRIGFLKTHDLTTLQALVHYLISLQGRYNRHAAWVLNGVVIRIAQKMGIHRDGTMLGLPPFETEMRRRLWFQILSMEFKTALMSGLGHSLLPRVWDTQEPKNVNDADLHPSATEPVKDREGPTEMIFVLITNKVARFIVESPGIEPIFLYHDEKVKKIPGAPSEEKIKEFRGLIDGLSKSLLELTDKYCDPAAGPLHQYTIEFQDIIMQRIRESLEPGDATIETHIDHMFKMAVESFESTVVSYRNSCKVAYLWFLRLQFHNDLFTFLAGQLSQRPSGPLVDRAWETVENILPYHPELLKVNASKENLLLASLLVKGWNMREEYCSTQMGITLNTPPYIEHLRSVVPQDYVKSENSSPSALSRIPKANRMVTREAASDQLSVSGPMDPTFDEFIGNYLDGADWDVFSRINLENPAFPGVPATGITPQVNATASDILPSTRIDHTDPNQTSHQFAMYGIDPQSAWQ
What is the function of this protein?
Transcriptional regulator; part of the gene cluster that mediates the biosynthesis of pyriculol and pyriculariol, two heptaketides that induce lesion formation upon application on rice leaves but are dispensable for pathogenicity (PubMed:27902426).  With TRF2, negatively regulates the expression of the gene cluster and the subsequent pyriculol and pyriculariol production (PubMed:27902426).
What are the official names of this protein?
Pyriculol/pyriculariol biosynthesis cluster transcription factor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS8_BACFN
Sequence: MKTLQELTRPNIWRLKPYSSARDEYSGAAASVFLDANENPYNLPHNRYPDPMQRDLKLELSKIKKVAPAHIFLGNGSDEAIDLVFRAFCEPGRDNVVAIDPTYGMYQVCADVNDVEYRKVLLHDDFQFSADELLAVADERTKMIFLCSPNNPTGNDLLRSEIIKVINDFEGLVILDEAYNDFSDEPSFLSELGKYPNLIILQTFSKAFGCAAIRLGMAFASEGIIGVLNKIKYPYNVNQLTQQQAIEMLHKYYEIERWVKTLKEERGYLEEAFVELPWVLQVFPSNANFFLARVTDAVKIYNYLVGEGIIVRNRNSISLCGNCLRVTVGTRAENAKLIGALKKYQ
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: MRAZ_LEPCP
Sequence: MADFHFQGTSALALDAKGRVTVPARHRESLVSLAGSQLTLTKHPEGCLMVFPRPVWEGFRAKVEALPMAASGWKRIFLGSAMDVEIDSGSRMLISPELRAAAGLVHDVLLIGMGNHLELWDAQRQASAEAAVLQQPMPDVLQDFSF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PDXY_LEIXX
Sequence: MKILSIQSAVAYGHVGNSAAVFPLQRIGVEVLPVYTVNFSNHTGYGAWRGPLIAPDEVREVITGIEERRVLGSIDAVLSGYQGSEGIGDVIVDAVARVKAADPHAVYACDPVMGNAASGCFVAPAIPDLLRDRVVPVADLITPNQFELGYLTGSTPDTLESTLASVEAARAMGPSTVLVTSVERPDRPEGTIEMLAVDDTGAWIVQTPRLPMKANGSGDVTAALFTAHYVRTGEAETALRKTVSSVYDLLASTLESGERELRLVESQEFYANPREQFAVSRVG
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: NDB2_HOFGE
Sequence: MNAKAFLAIFMIALLITDRAEAGWWNAFKSIGKKLLKSKLAKDITKMAKQRAKEYVVKKLNGPPEEEVAAIDALMNSLDY
What are the official names of this protein?
Venom protein HGE029, Non-disulfide-bridged peptide 3.7, NDBP-3.7.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS11_FUSNN
Sequence: MAKKTVAKIKKKSKNIPNGVAHIHSTFNNTIVAITDVDGKVVSWKSGGTSGFKGTKKGTPFAAQIAAEQAAQIAMENGMRKVEVKVKGPGSGREACIRSLQAAGLEVTKITDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MURA_DEIRA
Sequence: MQLTPLHVTGGRQLGGEIAVQHSKNAALPIIVATLLSSEPITLHGIPRLSDVYTILELMHHLGTRHAWVGPNSLTLHTPEIENTDAPYALVSKMRASFIVLGAILARAGTATVSMPGGCAWGPRPVDQHVKALRALGAEVIEDGGNFFAHREGSLNGSFVFELLTVGGTHNAILAAALGEGTVTLENASIDTDVVDVIEFLNALGARIEGAGTNTITIHGVKELHGGEYTVIPDRIEAGTFMMLAAATRSRLTLTNVRPDHLRAVTSKLAEMGVDIQEDGNRMVVDARGRDLKPVNVTTQSYPGFPTDLQPQMSALLATVPGTSVIQDPVYPDRLTHVAELHRMGATITVSGYTQVIQGGTLHAAPVKAADLRAGAALFIAGLTCEGETVIDGVQYLNRGYERLAERLRGIGGEVMQPEPMLAADD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC2_PROMT
Sequence: MTSSSPKTRKSSTKSKAKRGSKSKKAAEIIAVQRLSKTPPPFRNKVVDKKVLKNLVAWAFKHHGTAATAAMADNLKDLGFRYATQAAVSISVDDLKVPEAKQDLLGQAEELITATEECYRLGEITEVERHTKVIDTWTETNERLVDAVKKNFNQNDPLNSVWMMANSGARGNMSQVRQLVGMRGLMANPQGEIIDLPIRTNFREGLTVTEYVISSYGARKGLVDTALRTADSGYLTRRLVDVAQDVIVREEDCGTTRSILISAEDGKFGNRLVGRLTSEQVVNADEEVLAERDTPIDPQLSKKFEQSNMQGVRVRSPLTCEATRSVCRKCYGWALAHNQLVDLGEAVGIVAAQSIGEPGTQLTMRTFHTGGVSTAETGVVRSTLSGKVEFGSKARVRGYRTPHGVEAQQAEVDFNLSIVPTSGGKPQKIDIPIGSLLFVDNGQNIDIDVTVAQIASGTVQKSVEKATKDVICDLAGQVRYETIIQPREVTDRQGNITLKAQRLGRLWVLAGDVYNLPPNALPVVSGNVSVKEGQVLAEASQASEFGGEVRLRDSIGDSREVQIVTTSMTLDDFKLLEESTHSGEIWHLEAQDNTRYRLNTIPGSKIGNNEVIAELSDDRFKTETGGLIKYAPGLTIKKARSAKNGYEVSKGGTLLWIPQETHEINKDISLLMIKDRQWIEAGTEVVKDIFSQTAGIVTVTQKNDILREIIVRSGTFKLCKESKALDRFEGDGQIVNPGETIAKGIKTDSMVMVQSVETPEGKGLLLRSVEEFNIPDQAQLPELKHVKQPKGPSLGVKASQRLAYKDGELIKSVEGVELLKTQLMLETFDTTPQMTVDVEVIQDLNSKGDRLKLVILESILVRRDTTSDSSHGSTHTELQIENAQVVSAGDVVATTQILCKQEGVVQLPDAVDGDPVRRLIVEREEDTITIDSKGTTLLKVGQRVVDGDFVSKDQSIDACGEIENIDGKKVKLRLGRPYMVSPDSVLHVRDGDLVQRGDGLALLVFERQKTGDIVQGLPRIEELLEARRPRDSAILCKKSGTVDIKKGDDDDSVVVSIIEDNDVISEYPILLGRNVMVRNSQQVIAGEFLTDGPVNPHELLECFFTDLRDKKPLMDAAQEAIAKLQHRMVSEVQNVYKSQGVAIDDKHIEVIVRQMTSKVRIEDAGDTTFLPGELIELRQVEDTNQAISITGGAPSEFTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFSGFVEELNAEAGPHPDILAEDPAGYRRIQNLRPDYTVDMPSSPVAKNTAVLDDPSEEDLEATRSRHGIDPTTSNFAAFARPVGDDELSAEDQMPDPAALEGLQEEGLLSDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: MQO_BACCZ
Sequence: MSNMQQKTDVILIGAGIMSATLGSLLKELAPEWEIKVFEKLASAGEESSNEWNNAGTGHSALCELNYTSEKSDGSIDISKAVKVNEQFQLSRQFWAYLVKSKLIRNPQDFIMPLPHMSLVQGEKNVEFLKNRFEALSKNPLFQGMEFSDAPETLKKWLPLIMEGRTSNEPMAATKIDSGTDVNFGALTRMLFNYLKTKDVELNYKHSVENIKRTKNGLWEVKVHDMNSGKIEHHTAKFVFIGGGGGSLPLLQKTGIPESKHIGGFPVSGLFMVCKNQKVVEQHHAKVYGKAKVGAPPMSVPHLDTRYIDNKKALLFGPFAGFSPKFLKTGSNLDLIGSVKPNNVLTMLAAGVKEMGLTKYLIQQVMLSHEKRMEELREFIPNAKSEDWDIVVAGQRVQVIKDTDAGGKGTLQFGTEVVSAADGSIAALLGASPGASTAVHVMLEVLEKCFPSRMVEWEGKIKEMIPSYGISLTENPRLFQDLHTSTGRTLGLNEKETVHN
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: YMI3_YEAST
Sequence: MDYLHVYNNNQAHVPRTPPGRQCLSPVLPPIILALDQQHSLTFGYSSPRCLPTPILPSMSTNTPVHWSQQVVTIPVAVRNHAAMMPIITPMTSPRPQFEATAPSPPLAPVAIKLPDLKLPPSPVPSTVEDRVSHPILPKIVIGNGGGRDVERDSTEELIRKIPNYIGCAKTKAQLSKVRSGKQLIACAQEYHHPVNKDEIENINNILNFRDFIFKHPKSSFEFLCTLSFEQFVRVYSFISFIYRTKKINKNKYELVCEMNVHEQLSNKRIQRTRTPEKYKIHLICESKLILTFNHCTKTVKFESINGGHCHPISANHIIKPSLFLTHCINKCYQTVSDPTDLKLALRDALEALDHERIGLSFLKRRHFKCSHQASSLSNASATLKKQEDHDTFGVHTGIIHTANFFMFNASSDIFQRN
What are the official names of this protein?
Putative uncharacterized protein YML083C.
Protein: MUKB_ECOSE
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADCAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRAPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: DNLJ_POLAQ
Sequence: MSSNSPTNLADRYAFLQAELARLEHAYYVLDNPLLPDIEYDRLYRELLDIEAAHPQWVTSESLSQRVGGTALKEFDSVTHAVPMLSLNNAFEDSELIAFDRRCREALHVEHVAYAGELKFDGLAISLRYENGTLVTAATRGDGASGEDVTANIKTIRAIPLKLTGKNIPEILEVRGEVFMYLKDFEKMNRQAAELGEKEFANPRNAAAGSLRQLDSKITAKRPLSFFAYGLGALEPQSWLPKTHEELLNAYVELGLPVCSERRVLHSVEEILAFYNEIGAKRDSLPYDIDGVVYKVNSFAEQAKLGFVSRAPRFALAHKYPAQEALTTVLGIDVQVGRTGAITPVARLAPVEVGGVTVTNATLHNEDEVKRKDVRIGDTVSVRRAGDVIPEVVSVIKERRPSDAKEFVMPSRCPVCDSHIERLADEAVARCSGGLFCGAQRKQALIHFAHRRALDIEGLGEKIVDQLVDQNLVRTPADLYRLGFTALANLERMGEKSADNLIQAINQSRNTTLARFIFALGIRHVGETTAKDLANHYQSMHALMDASVEELLTVKDVGPVVADSITSFMQEAHNREVIEQLLASGMQLSVEEKIISAAVFGKTFVLTGTFPTMTRDEAKDLLEKAGAKVAGSVSKKTDYVVAGTDAGSKLAKAEELGVPVIDEEEMLNLLK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DZIP1_DROME
Sequence: MGFKGKYPQMVRETGFKLRQYRDGPLDWRLMGSYETERILREQNFELVDKALTHLSEAPLGTVLETHILDSGIAKYFVMSQYAIQYLMCCRTYLDECVTDLKEAHTTAQEEIATLRKSLSESNNEVVQLHKRITQIEAIREVVYPCHLCTKNFISNEALNVHIGRKHRVASPPSLTSATGKEKDRDKATDVHLINTIKMELEIKQLKERLNAAERNIKERSTGSKRVSPRQEQRHVGIQSNLAEPKEKDEDSGEARQSEASERKEQLTGLAERLSNFEEWQTQLKQSNEQFIQDINKRLEGLSHALEQSKQASASTPPLEDRVATPCLEDLERILTEKVAEIGKVSAHRLEEVVYHLEEGYKEKLGALERELKQLSVQKVQPEPVQTVPVASKIPKPVVRKEETNIDRIRKQVESEFLKQKHDDDTYSIEEAPRKGSEKPFPQLVTQVQVVEKEQPSAGSSDSNPTYTKSPREPAPNKQETKEATDVSDSLSQEETENEEERSLTEEEGTDVPTSGSEAAREDPTPKTIKPSGRIIKSPQKPLTRKDARKMVNRKLMSHGFDMKSKGISHNSLKRVNSELTEHRNKLKLQHPHFYATRNRIRKFVEKLCSAKFSERAEMLLKHKSPLKPMEVPGKGIPRSAISEKSEEDIASSQGEEQTDEQTDSSEQQTRSPSPQRLVSRDFKARLEEILVKPAATIRGASKSSLSSRPVPLPRKRVMFNTTEDGKSFNDSDDNLK
What is the function of this protein?
Component of the DZIP1-Fam92-Cby complex which promotes ciliogenesis in sensory neurons and spermatocytes by acting downstream of Cep290 to initiate early ciliary membrane formation and thus transition zone (TZ) assembly (PubMed:31821146, PubMed:33370260).  During spermatogenesis, also regulates distal elongation of the basal-body and their docking (anchoring) to the plasma membrane and as a consequence, regulates the initiation and proper elongation of axonemal microtubules (PubMed:31821146).  Within the complex, required to recruit or stabilize Rab8, Fam92 and Cby at the distal basal body of cilia to promote early ciliary membrane formation and initiate TZ assembly (PubMed:31821146).  Also acts with Fam92 to restrict cep290 localization to the proximal part of the TZ (PubMed:31821146).  May also be involved in recruitment or stabilization of Mks1 at the TZ (PubMed:31821146).
What are the official names of this protein?
Cilium assembly protein DZIP1L, DAZ-interacting zinc finger protein 1-like, Zinc finger protein DZIP1.
What is the protein family that this protein belongs to?
Belongs to the DZIP C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone (TZ) in type I sensory neurons and spermatocytes (PubMed:31821146, PubMed:33370260). In spermatocytes, localizes along the TZ membranes (PubMed:33370260). Localizes at the centriolar distal ends of early spermatocytes and in elongating spermatids, when the TZ migrates away from the basal body, localizes at the ring centriole (PubMed:31821146, PubMed:33370260). In sensory neurons, localizes between the transition fiber and TZ core components (PubMed:33370260).
Protein: METK_RHOOB
Sequence: MSQSGSRLFTSESVTEGHPDKICDAISDSILDALLTDDPRARVAVETLVTTGQVHVAGEVTTTAYADIPKIVRDTVLEIGYDSSAKGFDGNSCGVNVAIGAQSPEIAQGVDHSHEVRTGELSDDEIDRQGAGDQGLMFGFATTDTPELMPLPIALAHRLSRRLTEVRKSGVLPYLRPDGKTQVTIEYDGDKAVRLDTVVISTQHAADIDLDNLLTPDLREKVLGSVLAEIDMPELDVSDIRLLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAMRWVAKNAVAAGLADRIEVQVAYAIGKAAPVGLFVETFGTEKTDPARIQQAITETFDLRPGAIIRDLDLLRPIYAQTAAYGHFGRTDIDLPWESIDRAEKLRAAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.