PharMolix/UniProtQA huggingface dataset:
Protein: COQ9_DICDI
Sequence: MISNILKKSNSLFLRSTLSSNKFTNVTILRNSLFLNNNNNDNNTNIKQTYNKINFFSTTVPNQNEKIELKQEQIKQEQQQQPEQQPEQQTNKINNEIELKIKILENSLKYVNSYGWTSEAVSKACIEMGYPPITQGILGEDSAYELALYFVTKCNTDLMIKLSDAENSEQQLLSGLSKKEKVKLALKLRLSMIKPFIGRWSEAMQLLANPKNIVNSSPSMLTLVDNIWYLVGDKSSDFDWYAKRGLLIALYTSAELFMLSDTSVDHSNTWRFVDDRVDDLIKTIKFKNDIEETVGITLNTFLQKIKK
What is the function of this protein?
Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
What are the official names of this protein?
Probable ubiquinone biosynthesis protein coq9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COQ9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CXG3_MOUSE
Sequence: MLLLELPIKCRMCGRFLRQLLAQESQHSTPVGRFLLPMLMGFRLLILVSSGPGVFGNDENEFICHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGKENKEQETQISKGDHSKDVSGAKSLKLLWAYVAHLGVRLALEGAALGVQYNLYGFKMSSTFICREDPCIGSTTCFQSHPSEKTIFLNIMFGISGACFLFIFLELALLGLGRFWRIYKHKLSFLKKLPTSESSVRSKDTTDELSVVEAKEPF
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction gamma-3 protein, Connexin-29, Cx29, Gap junction epsilon-1 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Gamma-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: TRMD_BURA4
Sequence: MNQVTESAVQFDVVTLFPEMFRALTDWGITSRAVKQERFGLRTWNPRDFTTDNYRTVDDRPYGGGPGMVMLAKPLEAAINAAKAAQAELGVASTRVVMMSPQGAPFTHERAVRMAQEPGVIVLCGRYEAIDQRLLDRCVDEEISLGDFVLSGGELPAMAMMDAVVRLLPGVLNDAQSAVQDSFVDGLLDCPHYTRPEEYEGMRVPDVLLGGHHAEIERWRRQEALKNTLRKRPDLIVRARREKLLSRADEAWLANLAREAKNAS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_STRSV
Sequence: MRCPKCGGNKSSVVDSRQAEDGNTIRRRRECEECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEIEEIVNRIEQKVRSQSDNEINSEYIGSLVMDELAELDEITYVRFASVYRSFKDVGELESLLKQITKGSKKKKDK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: METK_HAEIN
Sequence: MSSYLFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAWVDIENLTRKVICDIGYEHSEMGFDGHSCAVLNAIGKQSADINQGVDRENPLDQGAGDQGIMFGYATNETDVLMPAAITYAHRLMEKQSEVRKSGKLAWLRPDAKSQVTLKYEDNKIVGVDAVVLSTQHSEEVSQKDLHEGVMEEIIKPVLPSEWLSKETKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKEPSKVDRSAAYAARYVAKNIVAAGLADRCEIQLSYAIGVAEPTSIMVETFGTGKVANELLVSLVREFFDLRPYGLIKMLDLIQPIYRETAAYGHFGREQFPWEKVDRAEDLRIAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIF1_YEAS7
Sequence: MDAQLEWASSLVPKRQLQQQQQQEQQQQQQDFHKDQLMTVGMRIRQRVDQGYASRTPSTSDASLQPGVIRDYSSVIVPQFTRSPLPTANSLPPMLINQRTMSTEASSLEKWDVAEPAAEHETMVNGSKRRL
What is the function of this protein?
Mediates the nuclear localization of RNR2 and RNR4, 2 subunits of the ribonucleotide reductase.
What are the official names of this protein?
Damage-regulated import facilitator 1.
What is the protein family that this protein belongs to?
Belongs to the DIF1/spd1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SUB1_PSED2
Sequence: MKFSQSLIALAACFLPLIAAAPVEAQHAKIRSPRAQDIIPDSYIVVFNKGVNDADIESEFSSVSRILSKRRSAHKGVGHKYNITGFKGYQIETDTGSIGEIAASPLVAWIEMDGKVQANALETRSGATWGLGRISHKATGSNSYIYDGSAGSGSTVYVLDTGIYIEHSEFEGRAKWGANYISGSPDTDENGHGTHCAGTIAGATYGVASKANLVAVKVLDRDGFGATSATIAGINFVGQNGKDGKSVISMSLRGHYSAAVNSAVESTVSNGVTIVVAAGNDGDDASNYSPASAKNAITVGSVDSTDTRASSSNYGSVVDIFAPGVNVKSASIGGKSAFSIKSGTSMATPHVAGLAAYLIGLGGLSSPAAIASKIASIGTKGSVKDPKGSVNLIAYNGNGA
What is the function of this protein?
Major secreted subtilisin-like serine endopeptidase (PubMed:25785714).  Mediates the degradation of collagen, the major structural protein in the mammalian host.  Degrades the nonhelical regions of collagen that function in the cross-linking of the helical components (By similarity).  May function as virulence factor involved in epidermal wing necrosis observed in white nose syndrome (WNS) in bats (Probable).
What are the official names of this protein?
Subtilisin-like protease 1, Destructin-2, Serine protease 1, PdSP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTCRA_BOVIN
Sequence: MAESWLLLLLALGCPALPTEVTTLLRPAQQGMGSTPFPSLAPPITLLVDGKQQTLVVCLVLDVAPPGFESPIWFSAGNGSSLDAFTYGPSPAEDGTWTRLAQLSLYSEELAAWDTLVCHTGPGAGDHGQSTQPLQLSGDASSARTCLWEPLRGTRALVLRLGALRLLLFKLLLLDVLLTCGRLHAPPAARGDPAGASGPGAPSLPAPHEVPRADSRLLPQPPPPRGSSSGPADRIRRNHGGTTGRGLSVSASPPLEPRDRRRRVHTRRPRRDPRNPVWEEGPPVLRAWSSGPSFSLSTSSLGAFLCNLPPPADPSFPGG
What is the function of this protein?
The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development.
What are the official names of this protein?
Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: STHA_PHOLL
Sequence: MQHIHFDAIVIGSGPGGEGAAMGLVKQGKSVAVIERYNNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDNSRVLRSSFAEILRRAEMVINQQTRMRQGFYERNGCRMFSGEATFIDDHRVSVRYADDNHDILSADKIIIATGSRPYCPPDVDFTHSRIYNSDSILKLDHEPRHVIIYGAGVIGCEYASIFRGLGVKVDLINTRNHLLAFLDQEMSDALSYHFWNSGIVIRHNEEYSKIEGVDDGVIVHLKSGKKVKADCLLYANGRTGNTDTLGLKNVGLEADSRGLLKVNKIYQTSNENIYAVGDVIGYPSLASAAYDQGRIAAQAMTKGNAEVHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIAGMNVGSLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGESNTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIXA_ECOSE
Sequence: MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVDAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: DAGK_STAAT
Sequence: MRKRARIIYNPTSGKELFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE
What is the function of this protein?
Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid.  Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway.
What are the official names of this protein?
Diacylglycerol kinase, DAG kinase, DAGK.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
Protein: Y2046_GRABC
Sequence: MTEALPFWKTKHLTELTREEWESLCDGCGRCCLHKLRDEETEELAFTNVSCRLLDTQSCRCTSYATRFRKVPDCISLTPALVAEIDWLPPSCAYRIVLNGKDLPWWHPLVSGDPETVHQAGISVRGRAIDEREAGPLEDYIVSWPGRFPRPRRPRQEPAGKTADES
What are the official names of this protein?
UPF0260 protein GbCGDNIH1_2046.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: F16PA_HALSA
Sequence: MADVIDAVFDAIADAAPEVRAGLPDHRATRDDQNASGDTQLEADVWADDLLFDRTESIEGVNWYASEERDAVVTVGDAEGGYAVALDPLDGSSNVKSNNPCGTVVGIYDQPLPAPGSSLVAAGFVLYGPTTTMVVARDDTVRESLVSETGATTDLGPVELPADPTVYGFGGRVPDWTPAFESFVRDVEDDLKLRYGGAMIADVNQVLVYGGVFGYPGMESAPDGKLRAQFEALPIAYIVETAGGASSDGTQSLLDVAPTRLHERTPTFVGTDDVIAALDAALPDHTN
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_PSE14
Sequence: MSITIKLGQLAEFLGATLRGDKDKDITGLAALQEAGPGQISFLAKSQYRKFLVDAQAAAVLLKPADADSYTGDALLVPDPYLAYARISHFFDPKPKGVAGVHPTAVIADDAQVDPAASIGAFVVIESGARIAAGVTIGAHSFIGARCEIGEGGWLAPRVTLYHDVRIGKHVVIQSGAVLGGEGFGFANEKGVWQKIAQIGGVTLGDDVEVGVNTAIDRGALADTRIGNGVKLDNQIQIAHNVQVGDHTAMAACVGISGSTKIGKHCMLAGGVGLVGHIDICDGVYITGMTMVTHSITEPGSYSSGTAMQPAAEWRKSAARLRKIDDMARRLQKLEKAVETVTCADNRSSDG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: PB1F2_I01A3
Sequence: MEQEQDTPWTQSTEHINIQKRGNGQRTQRPEHPNSIRLMDHCLRIMSRVGMHRQIVYWKQWLSLKSPTQGSLKTRVLKRWKLFSKQEWIN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: GLPK_PARPJ
Sequence: MQDQYILALDQGTTSSRAMLFDRLGNIVSTAQKEFQQIYPRPGWVEHDPQEIWSTQAGVAAEAVTRAGMNGTSIAAIGITNQRETTIVWDRETGHPIYNAIVWQDRRTADFCDQLKEQGLEEKVRAKTGLPIDSYFSATKIRWILDNVEGAREKARQGRLAFGTVDSWLVWNFTKGGLHVTDVTNASRTMLFNIHSLKWDDELLEALDIPRSMLPEVRASSEVYGPTKTTVFASKIPLAGIAGDQHAALFGQMCTESGMVKNTYGTGCFLVMNTGDKPIESKNNLVTTIAWQIGDQINYALEGSIFIGGAVVQWLRDGLGIIKNAAEIETLARSVSHSDGVYLVPAFAGLGAPHWNARARGTLFGVTRGTSSAHIARAALDSIAYQSLDVLKAMEADSGIRIGELRVDGGACANNLLMQFQADILGVDAVRPKVAETTALGAAYLAGLAVGYWKDVDELQSQWKLDRRFTPALPHAEVKQCLDGWQRAIRAAKAWADTP
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: HSL27_DICDI
Sequence: MTILASICKLGNTKSTSSSIGSSYSSAVSFGSNSVSCGECGGDGPSFPNASPRTGVKAGVNVDGLLGAIGKTVNGMLISPNGGGGGMGMGGGSCGCN
What are the official names of this protein?
HssA/B-like protein 27, Protein 7E.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: YGFZ_SHIF8
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQVTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVKEGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKR1_CAEEL
Sequence: MNQEFLIQLGERACKNAENLTLPAELEGIFFCAPSSRESLATQVFVAIAFVLLMATAIIGNSVVMWIIYQHKVMHYGFNYFLFNMAFADLLIALFNVGTSWTYNLYYDWWYGDLCTLTSFFGIAPTTVSVCSMMALSWDRCQAVVNPLQKRPLSRKRSVIAILIIWVVSTVTALPFAIAASVNSLYTYDVVTSTVSKAHVCSAPVNTFFEKVLFGIQYALPIIILGSTFTRIAVAFRATNEATDSSLKNNHTRAKSKAVKMLFLMVVAFVVCWLPYHIYHAFALEEFFDAARGKYAYLLIYWIAMSSCAYNPIIYCFANERFRIGFRYVFRWIPVIDCKKEQYEYSQLFPDKMRSMAISLQKGRVNSSCLDKKVKENSSQDLVCVMHSEKNTKKYSKVHLLSCHER
What is the function of this protein?
Not known.  Putative receptor.
What are the official names of this protein?
Probable G-protein coupled receptor tkr-1, Tachykinin receptor family protein 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H2BWT_HUMAN
Sequence: MLRTEVPRLPRSTTAIVWSCHLMATASAMAGPSSETTSEEQLITQEPKEANSTTSQKQSKQRKRGRHGPRRCHSNCRGDSFATYFRRVLKQVHQGLSLSREAVSVMDSLVHDILDRIATEAGHLARSTKRQTITAWETRMAVRLLLPGQMGKLAESEGTKAVLRTSLYAIQQQRK
What is the function of this protein?
Atypical histone H2B.  Nucleosomes containing it are structurally and dynamically indistinguishable from those containing conventional H2B.  However, unlike conventional H2B, does not recruit chromosome condensation factors and does not participate in the assembly of mitotic chromosomes.  May be important for telomere function.
What are the official names of this protein?
Histone H2B type W-T, H2B histone family member W testis-specific, H2B.W histone 1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
Protein: HSLO_SERP5
Sequence: MSNHDQLHRYLFENYAVRGELVTVSETYQQVLNNHDYPAPVKKLLGELLVATSLLTATLKFDGDITVQLQGDGPLKLAVINGNNRQEMRGVARVQSEIADDSTLHQMIGNGVMVITIAPTEGERYQGVVALEGETLAECLEAYFRQSEQLPTRLFIRTGESEGQPAAGGMLLQVLPAQDGNADDFDHLVQLTNTVKSEELFGLPANEVLYRLYHQEEVTLYEPQDVVFRCTCSRQRCADALITLPAEEVAQMLEQDGNIDMHCDYCGNHYVFDAMDVAALYTGNTGESEQLH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCF1_KOMPG
Sequence: MASVNYPSSFDKKDEFEDMSILDKIWFRCKQQPLVPIGCLATCVAVALAAKGVRTGDRVNAQKWFRWRVGLQGLTLVALVGGSYIYDRQQVTQRKTDEDLAREKAQHRQDLWIQELERRDQETKRNKERARLARARLEAERSTGILDDEPPK
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: MRGB5_RAT
Sequence: MPDSPTESYGPDREYHVFISLFLCRNTSGKFLSVGPATPGWSINNTVVKENYYTEKLSCIITFNTLNFLTATISVVGTAGNATVLRLLGFHMHRYAFSVYVFNLAGADFLYLCTQTVYSLECVLQFDNSYFYFLLTILMFAYLAALCMIPAISTERCLSVTWPIWYHCQRPRHTSATVCALFWAFSLLLRLLLGQGCGFLFGKYDYYFCRYCSFITTAFLIVLFVVPFVSSLAMLTKIICGSHRIPVTRFYVTIAVTVLVFTFFGLPVGIISLLLPRIVVFRGVFYIYKIVTFLYSVNCCANPIIYFLIGSIRHHRLQRQSLKLLLQRAMQDTPEEEGGVKGPSQKSNELEIV
What is the function of this protein?
Orphan receptor.  Probably involved in the function of nociceptive neurons.  May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity).
What are the official names of this protein?
Mas-related G-protein coupled receptor member B5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL23_MYCLE
Sequence: MATIADSRDIILAPVISEKSYGLLDDNVYTFVVHPDSNKTQIKIAIEKIFSVKVASVNTSNRKGKCKRTRTGFGRRKNTKRAIVTLAPGSKSIDLFGTPA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: UREG_MYCTU
Sequence: MATHSHPHSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGELSLAVLTNDIYTTEDADFLRTHAVLPDDRIAAVQTGGCPHTAIRDDITANLDAIDELMAAHDALDLILVESGGDNLTATFSSGLVDAQIFVIDVAGGDKVPRKGGPGVTYSDLLVVNKTDLAALVGADLAVMARDADAVRDGRPTVLQSLTEDPAASDVVAWVRSQLAADGV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_RHEAM
Sequence: VLSGPDKTNVKNVFAKIGGHADAYGAETLERMFTTYPQTKTYFPHFDLHHGSAQIKTHGKKVVSALIDAANNIDDIYGALSKLSDLHAQKLRVDPVNFKLLGQCFLVVVAIHHPSLLTPEVHASLDKFLCAVGAVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PDXS_HAEIN
Sequence: MAENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMALERIPADIRAVGGVSRMSDPKMIKEIQGAVSIPVMAKVRIGHFVEAQILEAIEIDYIDESEVLSPADNRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAVRHMRMMSQEIRRIQNLREDELYVAAKDLQVPVELVQYVHKHGKLPVVNFAAGGIATPADAALMMQLGAEGVFVGSGIFKSGDPIKRASAIVKAVTNYRNPQILAQISEDLGEAMVGINENEIQILMAERGK
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: RL33_HELPJ
Sequence: MKVKIGLKCSDCEDINYSTTKNAKTNTEKLELKKFCPRENKHTLHKEIKLKS
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: LOADL_BPR69
Sequence: MITINSKEHILEQKYRPSSIDECILPAYDHETFKSLVSKGKLPHIILHSPSPGTGKTTVAKALCNDINAEMMFVNGSDCKIDFVRGPLTAFARSVSMEGKPKVIVIDEFDRSGLAESQRHLRTFMEEFSSNCSIIITANNIDGIIEPLRSRCRVIEFGRPTEEDKISMMKKMIHRMVEICKNENIEIADMKVVAALVKKNFPDFRRTIGQLDQYSSKGVLDAGILSIVTNDRGTVSDVIEAMKNKDIKQLRALAPKYAADYSWFIDKLVSECYDQVAPGKSIISLYEIAGENNKFHGLASNIELHVMYMLLQLTCELTWK
What is the function of this protein?
Forms the sliding-clamp-loader together with the small subunit.  Functions as an ATPase enzyme.  The clamp loader holds the clamp in an open conformation and places it onto the DNA.  4 ATP molecules must bind to the sliding-clamp-loader before the latter can open the sliding clamp.  ATP hydrolysis triggers the detachment of the sliding clamp from the sliding-clamp-loader, freeing the sliding clamp to track along DNA.
What are the official names of this protein?
Sliding-clamp-loader large subunit, Clamp loader gp44 subunit, Gene product 44, gp44.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae sliding-clamp-loader large subunit family.
Protein: RL25_EHRRG
Sequence: MTDQTIVKMNAELRNSVGTGPSRTLRRNGAIPAVVYGKHRSPLSIYLSDREFLSKYRSAALSTHLIELEIGEKKEYVLMRDIQKHPVTDRIQHVDFQFIDHGTEIKIEVPLVFVNEQRCVGVKKGGVLNILHRTLHIKCLPNAILQSIEVDLANLTIGHSIHVSDLNLPSEVTVVMKEHNPTLVTISGTSSDQDTSGGESSGTTTSED
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: DNLJ_HAEDU
Sequence: MPLFSQFELSNNITPTQLEALRDQLREYEYHYHVLNNPLVPDAEYDRLINQLKNIEQQYPELITPDSPTQRVGAKPLAGFAQVAHEMPMLSLDNAFSETDLDNFLRRIENYLSLDANQLTFCCEPKLDGLAVSILYIDGVLQLAATRGDGTTGENITANVRTIRNIPLKLKMANPPHRLEIRGEIFMPLKGFNALNQRALAKGEKSFANPRNAAAGSLRQLDPQITRQRPLMLNAYGIGVYESNYQRLPTSHYARLEWLKSIGIPVNAEIRLARGYPQLLAFYADIQAKRADLGYDIDGTVLKVDDITIQETLGFISRSPRWAIAYKFPAQEEMTILKDVEFQVGRTGAITPVAKLEPTLVAGVTVSNATLHNGDEIERLGVAIGDTVIIRRAGDVIPQIIGIVADRRPANAKKIVFPTACPVCHSAVIRIAGEAVARCTGGLFCPAQRKEALKHFVSRKAMNIDGVGEKLIEQLMARELIHTPADLFKLDPLSLMRLERMGEKSAQNALNSIEKAKHTTLARFLFSLGIRDVGETTALNLANHFGSLENIRTANVEQLKEVQDVGEVVANRLVCFWQEQHNVAVVEELIAQGVHWDNIVQLEIADNPLKDKNVVLTGTLTQFSRDQARKLLQQLGCKVSSAVSTKTDFLIAGEKAGTKLTKAEQLGIRILDEHAFADLIKQLEYE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.