PharMolix/UniProtQA huggingface dataset:
Protein: SSRP1_CHICK
Sequence: MADTLEFNEIYQEVKGSMNDGRLRLSRQGVIFKNSKTGKVDNIQASELAEGVWRRVALGHGLKLLTKNGHVYKYDGFRESEFDKLSDFFKAHYRLELAEKDLCVKGWNWGTVRFGGQLLSFDIGEQPVFEIPLSNVSQCTTGKNEVTLEFHQNDDAEVSLMEVRFYVPPTQEDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARGTTTTRSFDFEIETKQGTQYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGMKQSYDEYADSDEDQHDAYLERMKEEGKIREENANDSSDGSGEETDESFNPGEEDDDVAEEFDSNASASSSSGDGDSDRGEKKPAKKAKIVKDRKPRKKQVESKKGKDPNAPKRPMSAYMLWLNANREKIKSDHPGISITDLSKKAGELWKAMSKEKKEEWDRKAEDAKRDYEKAMKEYSVGNKSESSKMERSKKKKKKQEKQMKGKGEKKGAASKSSSSTKSSAKTMSESFKSKEFVSSDESSSAESKKEDSEDESGASPAQSSEDSASGSD
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.  Binds specifically to double-stranded DNA (By similarity).
What are the official names of this protein?
FACT complex subunit SSRP1, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, T160.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Nucleus, nucleolus. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Protein: EFTU_GLOMP
Sequence: KNMITGAAQMDGGILVVSAADGPMPQTREHILLAKQVGVPSLVVFLNKEDQVDDAELLELVELEVRELLSIYDFPGDDIPIVIGSALKAVEALTATPTTKKGDNEWVDKILKLMDEVDEYIPTPEREIDKPFLMAVEDVFSITGRGTVATGRIERGKIKVGETVELVGIRNTRSTTVTGVEMFQKVLEEGMAGDNVGLLLRGIQKEDIERGMVIAKPGSITPHTQFEGEVYVLTK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PROM9
Sequence: MLFNSLLTNFAALEVGQHLYWQIGNIRLHGQVFLTSWILLGALLVFISLGTKKMENDPKGLQNLLEFLWDYIRDLARTQIGEKVYRDWMPFIGTLFLFVFVSNWGGALIPWRLIKLPSGELGAPTADINTTIALALLVSLSYFYAGLSNKGWRYFEYYVHPTPIMLPFKILEDFTKPLSLSFRLFGNILADELVVGVLVFLVPLILPIPVMFLGLFTSAIQALIFATLAAYYIGEAVEEHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: ARMC1_HUMAN
Sequence: MNSSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNMADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW
What is the function of this protein?
In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
What are the official names of this protein?
Armadillo repeat-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Mitochondrion outer membrane. Note=Associates with the outer mitochondrion membrane, most likely through its C-terminus (PubMed:31644573). Not integrated into the mitochondrial outer membrane (PubMed:31644573).
Protein: RL23_COXB2
Sequence: MNEERLFKILLAPHISEKGALTTGQYVFEVMPDATKPEIKRAVEKQFNVTVKSVRTCNVKGKTTRFRQVRGRRKNWKKAYVMLAPGSEIDIAAGE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SSRP_ECOL5
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNSHR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL22_BUCAI
Sequence: METLAQHRQARSSAQKVRLIVDLIRGKKVPQALNILTYTNKKAAFLVKKVVESAVANAEHNDGADIDKLRIKKIFVNEGSTMKRMMPRAKGRADRILKRTSHITVIVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CYSG2_YERPP
Sequence: MDYLPLFADLKQRPVLIVGGGEVAARKIELLHRAGAQVWVVAQTLSSELEQQYQDGRIHWLAQDFLPEQLDNVFLVIAATNDTVLNAAVFAAADQRCILANVVDDQPLCSFIFPSIVDRSPLVVAISSSGQAPVLARILREKLEALLPTRLSDMAAIAGRWRGRVKQHMASMGERRRFWEHAFSGRFASLISRGQLTEAENELQLSLEGQHRALGEVALVGAGPGDAGLLTLRGLQVMQQADVVLYDHLVSPEVLDLVRRDAERICVGKRAGAHSVTQEATNQLLVTLAQQGKRVVRLKGGDPFIFGRGGEELQVVAQAGIPFQVVPGVTAAAGATAYAGIPLTHRDHAQSVTFITGHCRPDGDDLDWQTLARGRQTLAIYMGTVKAAAISQQLIAHGRSSTTPVAVIGRGTRVDQQVLIGTLAQLESLAQQAPTPALLVIGEVVNLHHQIAWFGQQPQTESAISPSVVNLA
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: RUTB_ECO27
Sequence: MTTLTARPEAITFDPQQTALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNYHKSNALKTMRNQPLLQGKLLTKGSWDYQLVDELMPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSSTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: YL477_MIMIV
Sequence: MDTSTISRNFGYIKSKPDKRDVLITFDKKTIKTFKLTANIKPKIIDGIFDLRKIVTLPQALSEIDQGTLGSCTANAIAYAYAFAEIKQHNRNTFMPSRLFIYYNERMLENSIDEDSGAQIRTGIKTINKYGVCDEHHWVYDPLKFRVKPPIEAYEEAKVAKSVKYARIDFTKDTTIDDRIEHIKRALLSGFPIVFGFVVFESFMSQDVTKTGIVNMPKSYEQEIGGHAVCAVGFNENDKTFIVKNSWGSKWGLNGYFNMPYKYVADENLASDFWIIQEVTDPIINNFDPNDINPDAINLDVNINSGGVVHN
What are the official names of this protein?
Uncharacterized peptidase C1-like protein L477.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: ARGR_PARD8
Sequence: MSTKKERLDAICGIIQTKVISNQEELLKELEDSGFSVTQATLSRDIKQLKVAKVHDGNGDYVYRLPEESISKQAQPEGKKKPNIEFSGNLAVVKTRPGYAMGIASDIDSHAPSEILATIAGDDTILVIPRNGVSQEKVIAALSHFI
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_ORYSJ
Sequence: MADVEVETEVAAGAQPKKRTFRKYSYRGVDLDALLDMSTDDLVQLFPARARRRFQRGLKRKPMALIKKLRKAKKDAPAGEKPEPVRTHLRNMIIVPEMIGSIVGVYNGKTFNQVEIKPEMIGHYLAEFSISYKPVKHGRPGIGATHSSRFIPLK
What are the official names of this protein?
40S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: DADA_BURM9
Sequence: MRVVILGSGVVGVASAYYLARAGHEVTVIDREAGPALDTSFANAGQISPGYAAPWAAPGVPLKAVKWMFEKHAPLAIRLDGTRFQLQWMWQMLRNCTTERYALNKGRMVRLAEYSRDCLQALRAETAIQYEGRTGGTLQVFRTQQQLDGAAKDIAVLREANVPFELLSSDELKKAEPALAAVSHKLTGGLRLPGDETGDCQLFTTRLAALAEQLGVKFRFNTRIDALAVAGGKIAGVQCGGEMVRADAYVVALGSYSTNLVASLVKIPVYPLKGYSITAPIVDAAKAPVSTVLDETYKIAITRFDDRIRVGGMAEIVGFDKRLRDARRGTLEMCVNDLFPGGGDTAKATFWTGLRPMTPDGTPIVGRTPVPNLFLNTGHGTLGWTMSCGSGQLLADLMSGKKPAIRADDLSVHRYLSETDGEHRPAYA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: RL37A_THEKO
Sequence: MGRTTKVGSAGRFGPRYGLKIRRRVAAVEARMKQKHVCPVCGRKAVRRISTGIWQCQKCGATFAGGAYLPTTPAGKVAKRVTASKA
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: HDAC1_PONAB
Sequence: MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKLA
What is the function of this protein?
Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes.  Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (By similarity).  Also functions as deacetylase for non-histone targets, such as NR1D2, RELA, SP1, SP3 and TSHZ3.  Deacetylates SP proteins, SP1 and SP3, and regulates their function.  Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons.  Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitates transcriptional activation.  Deacetylates TSHZ3 and regulates its transcriptional repressor activity.  Deacetylates 'Lys-310' in RELA and thereby inhibits the transcriptional activity of NF-kappa-B.  Deacetylates NR1D2 and abrogates the effect of KAT5-mediated relieving of NR1D2 transcription repression activity (By similarity).  Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development.  Involved in CIART-mediated transcriptional repression of the circadian transcriptional activator: CLOCK-BMAL1 heterodimer.  Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex or CRY1 through histone deacetylation (By similarity).  In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones (By similarity).
What are the official names of this protein?
Histone deacetylase 1, HD1, Protein deacetylase HDAC1, Protein decrotonylase HDAC1.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: R1442_DANRE
Sequence: MSSSRYEPSWDVDLAPLLSCKLCLGEFPLEQMTTISQCQCIFCSLCLKQYVELLIKEGLETAISCPDSACPKQGHLLENEIECMVAGEVMQHYKRLQFEREVLLDPCRTWCPSSSCQAVCQLNEAEVQLPQPVQCPECSLRFCSACRADCHTGQACQEMLPITTFLPGENGSNLKSQEDEAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCKRGDDDPLPT
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes ube2l3 and ube2l6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase RNF144A-B, RING finger protein 144A-B.
What is the protein family that this protein belongs to?
Belongs to the RBR family. RNF144 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PURL_BRUC2
Sequence: MTISNTRDITPELIEAHGLKPDEYQRILELIGREPTFTELGIFSAMWNEHCSYKSSKKWLRTLPTSGPRVIQGPGENAGVVDIGDGDCVVFKMESHNHPSYIEPYQGAATGVGGILRDVFTMGARPVAAMNALRFGEPDHPKTRHLVSGVVSGVGGYGNAFGVPTVGGEVNFDKRYNGNILVNAFAAGLARHDGIFLSEAKGVGLPVVYLGAKTGRDGVGGATMASAEFDESIEEKRPTVQVGDPFTEKCLLEACLELMASGAVIAIQDMGAAGLTCSAVEMGAKGDLGIELILDHVPVREENMTAYEMMLSESQERMLMVLKPEKEAEAQAIFRKWGLDFAIVGKTTDDLRFRVIHQGEEVANLPIKDLGDEAPEYDRPWMEPGKHAPLPASNVPQVEDYSAALLKLIGSPDLSSRRWVYEQYDTLIQGNSLQVPGGDAGVIRVEGHETKALAFSSDVTPRYCEADPFEGGKQAVAECWRNITATGAEPLASTDNLNFGNPEKPEIMGQLVKAIEGIGEACRALDFPIVSGNVSLYNETNGQAILPTPTIAGVGLLPDWSQMAKIGGMQDGDTLVLLGGDGTHLGQSVYLRDLFDRADGPAPFVDLALEKRNGEFVRSAIRNGQVTACHDLSDGGLAIAVAEMAIKSGKGATLDAGDGLPHALLFGEDQARYVISATPEMAKLIALNAEGAGVPFRILGTVGGDRLKISKNVDVSVADLTQAYEGWFPNFMNGELTGNN
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM3A_CONVA
Sequence: MLKMGVVLFTVLVLFPLATLHLDAEQPVERYAENKQDINPDQRSGFLTFALRQGCCPPGVCQMAACNPPPCCP
What is the function of this protein?
Conotoxin with small effects on sodium (Nav), potassium (Kv) and calcium (Cav) currents.  At high concentration (10 uM), it has no effects on the peak sodium currents, but induces a ~10 mV shift in a polarizing direction in the current-voltage relationship.  At the same concentration, it increases 19% of the peak potassium currents but does not induce a shift in the current-voltage relationship.  At the same concentration, it inhibits 31% of the peak calcium currents but does not induce a shift in the current-voltage relationship.  On rat DRG neurons, it inhibits calcium channel currents with an IC(50)=19. 28 uM.  Moreover, at 10 uM, it inhibits 15. 32% of the human Cav1. 2/CACNA1C currents and 12. 86% of the human Cav2. 2/CACNA1B currents.
What are the official names of this protein?
Conotoxin Vr3a, Vr3-NPPP01.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOD_METFK
Sequence: MAEIRNYTMNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRGTEKLAENRTYLQSVPYMDRLDYVSMMVNEHAYVMAIEKLLGLEVPLRAQYIRVMFDEITRILNHLLWLGAHALDVGAMTVFLYAFREREDLFDCYEAVSGARMHAAYYRPGGVYRDLPDRMPQYEESTVRSKEDVKQLNENRQGSLLDFIEDFTNRFPAYVDEYETLLTDNRIWKQRTVGIGVVSPERAMALGMTGPMLRGSGVAWDLRKKQPYEVYDRLDFDIPIGVNGDCYDRYLVRIEEFRQSNRIIKQCIDWLRKNPGPVISDNTKVAPPPREEMKHDMEALIHHFKLFTEGFHVPAGEAYAAVEHPKGEFGIYLISDGANKPYRLKIRAPGFAHLAALDEMTRGHMIADLVAIIGTQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EFTS_METFK
Sequence: MAEITASMVKELRERTDAPMMDCKKALTEAEGDMARAEEILRVRFGNKASKAAGRVAAEGVVAVSIKADGKLGAIVEINSETDFCAKNADFLAFVAQVAEAAATEKPADVAALSALKIDGGSVEDIRTQLIGKIGENITVRRFAVTEAKGKLVSYVHGGKIGVLVDLVGGDETLGKDIAMHIAAAKPKSLDASGIPAELIEAERRVAIEKAKEAGKPEAMLDKIADGTVQKFLKEVTLLSQPFVKDDKQTIEQLLKANNASIASFTMYVVGEGIEKVVTDFAAEVAAAAKV
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1M_CARAU
Sequence: MLNTLMTHLINPLAYIVPVLLAVAFLTLIERKVLGYMQLRKGPNVVGPYGLLQPIADGVKLFIKEPVRPSTSSPFLFLAAPVLALTLAMTLWAPMPMPHPVTDLNLGILFILALSSLAVYSILGSGWASNSKYALIGALRAVAQTISYEVSLGLILLSVIIFSGGYTLQTFNTTQESIWLLIPAWPLAAMWYISTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFFLAEYANILLMNTLSAVLFLGASHIPNMPELTTINLMTKAALLSILFLWVRASYPRFRYDQLMHLVWKNFLPLTLAFVLWHTALPIALAGLPPQL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYC_ANADE
Sequence: MSIQVHDTLTAQKRELVPLEPGKLRLYVCGPTVYDYSHLGHARCYVVWDVVVRHLRARGLEVRFVRNFTDVDDKIIQRANERGEDPIALASRFADAFHEDMDALGNLRPDVEPRVSGHIPEIVALIARLVERGFAYAPGNGDVYYAVRKFPEYGRLSKRNLDDLIAGARVEPGEAKRDPLDFALWKAAKPGEPAWDSPWGKGRPGWHIECSAMTQKHLGAPIDLHAGGKDLVFPHHTNEIAQSVAATSDGLHAEDFARYWMHNGFVQIDDEKMSKSLGNFFTIRDVLARFDGEALRFFLLGTHYRRDFNFSDQVLAEAERRLSALYETVEKAERLGAGVEPGAEPAFVERARAALDDDFNTPQVLGIVAEAFTEANALADRKGKKSPEEKARLAAFARGARAVGAVLGILGRPPAQALSAIRDRAAARRGIDGSEVERLIAERAAARAAKDFARSDAIRDGLLARGVVLMDGPQGTTWKVE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABV2_PHOPR
Sequence: MIIEPVVKGVVARSAHPFGCQQAVRNQINYVRTADPVTDGPKKVLVLGASSGFGLASRISLAFGGSKADTIGISFERGPSEKGVGTAGWYNNIFFREEAENAGLIGKNFIGDAFTPQMRQQVIDYIKTEFGGQLDLVVYSLATGVRPNPETGELWRSSIKTMGEPVTGPTINIETDTMEQMTIGTATPAEIEDTEKVMGGEDWASWIDTLSEAGVLATGCKTVAYSYVGPKATYSIYHQGTLGRAKAHLHATADQLNDKMSEMGGEAYVSVCKALVTKASVFIPAFSPYILALFKVMKDKGVHEGCIEQMQRLYSQRLYGKNKIVPVDDSRLIRVDDWELEEDIQQQVSELMVKITPENFTTMGDYQGYKADFMQLNGFGLEGVDYQADIDFETLTQLVA
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] 2, ENR 2.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: PG036_VAR67
Sequence: MSSSTMDNNEPKVLEMVYDSPILPEGSSMDPNIINCINRHINMCLQHTYSSSIIAILDRFLMMNKDELNNTQCHIIKEFMTYEQMAIDHYGGYVNAILYQIRKRPNQHHTIDLFKKIKRTRYDTFKVDPVEFVKKVIGFVSILNKYKPVYSYVLYENVLYDELKCFIDYVETKYFQN
What is the function of this protein?
Plays a role in the inhibition of host innate immune response.  Within the host nucleus, inhibits activation of interferon-beta promoter by inhibiting IRF3 activation.
What are the official names of this protein?
Protein OPG036, Protein N2.
What is the protein family that this protein belongs to?
Belongs to the poxviridae OPG036 family.
Protein: MIAA_HELAH
Sequence: MSIYKDINIASAKPSLKERKNIKHYALDCLNIDEKNNAPLFKTLLEDAMKVSQKEILLIVGGSSFYLKSILEGLSSMPKLNNDQILKIEREIATLTNPYAFLKSIDPNMAFKIHSNDTYRIHKALEIFYATHTPPSEYFKKNPKKPFEHAITLFALCIEKTVLHNRIKQRTKNMLDCGLIEEIKALYTQYPKDSQPFKAIGVKESILYLEKQLTLKELEEAIVSNTIKLAKRQNTFNKTQFNNLYVGSVEEVRHAILKRSKSGIKE
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL33_RUBXD
Sequence: MVWRRVVRQLVTLACEECKRRNYHTRKNRRNTPDRLQLRKFCPWCRRHTAHRETR
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.