PharMolix/UniProtQA huggingface dataset:
Protein: BTUF_VIBCH
Sequence: MLVIRLIACTFLFITPSLLAKPFPAERIISLAPHATEIAYAAGLGDKLVAVSEYSDYPPQALELERVANHQTINIEKILTLKPDLIIAWPAGNPPRELAKLRQLGFTIYDSQTKTLDEIADNIEALSHYSANPEVGQKAAHDFRQRLQDLRTQYASNQPIRYFYQLSEKPIITLAQGHWPSEVFSLCGGVNIFADSEVPYPQVSIEQVLVKQPQVIFTSEHAIANGHMWRAWQAELSAVQNDQVWALNADWLNRPTPRTLDAVEQVCTYLKIAQKQ
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: THIO_THIRO
Sequence: MSDSIVHVTDDSFEDEVLKSLEPVLVDYWADWCGPCKMIAPVLDEIAGEYAGRIKVAKLNIDENPNTPRRYGIRGIPTLMLSRQSEVEATK
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: ATPA_PECCP
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGALDHDGFSAVEAIAPGVIERQSVDEPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTISNVVRKLEEHGALENTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLEDVELSKVGSFEAALLAYADREHGELLQQIDQTGAYNDEIEGKFKGILDTFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NOP12_ASHGO
Sequence: MSALNKLFGDERKRDLESNVAALFSQSSGPVDTLEVKSKPRTLLPVVSKRQETETAKPAEPTEIVEADLPRKRAKKAKKTNEDDDHLEEKYMQQVLKEDSDHESEAEAPTEPVVELKPSKRASRPDMKEEELAKAERTVFVGNVPHEAITDKKVYKEFKQLVAQRKLSKEDEDDEEQKAEKYAVESIRFRSIAFEEALPRKVAFVQQKLHHTRDSVNAYVVYAEKEAVTAACKLNGSVFHDHHLRFDSVAHPAPHDRKRSVFVGNLDFEESEESLWKHFMSCGPIEYVRIVRDPKTNVGKGFAYVQFADLVSVNKALLLNDKKMAVGKGRKLRVTRCRNMQKVQRQSNTAALPKLTDQQKTKLGRARKVLGKADRATLGKLTIEGTRATKGANTPNLRVKKARSKTGRVTKRSQAFKKAEANKKQK
What is the function of this protein?
Involved in pre-25S rRNA processing.
What are the official names of this protein?
Nucleolar protein 12.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM34 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SYE_MYCBO
Sequence: MTATETVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALRWLGLDWDEGPEVGGPYGPYRQSQRAEIYRDVLARLLAAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDAQRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGSVPDFALTRASGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALIRIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNLFAHRDRGFIPEGLLNYLALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTVRLRDHLDTHGHHIALDEAAFAAAAELVQTRIVVLGDAWELLKFFNDDQYVIDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDALIEGLALKPRKAFSPIRVAATGTTVSPPLFESLELLGRDRSMQRLRAARQLVGHA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LST8_XENLA
Sequence: MNSTQGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNSLEVTPDRSMIAAAGYQHIRMYDLNSNNPNPVINYDGVSKNITSVGFHEDGRWMYTGGEDCMARIWDLRSRNLQCQRIFQVNAPINCVFLHPNQAELIVGDQSGAIHIWDLKTDQNEQLIPETDVSINSVHIDPDASYMAAVNSSGNCFVWNLTGGLGEDLTQLIPKTKIPAHKRCALKCKFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSNNPGETSRGWMWDCAFSGDSQYIVTASSDNLARLWCVETGEIKREYSGHQKAVVCLAFNDSVLG
What are the official names of this protein?
Target of rapamycin complex subunit lst8, TORC subunit lst8, G protein beta subunit-like, Gable, Protein GbetaL, MTOR associated protein, LST8 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LST8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_SHEB5
Sequence: MSNKVHLGHTARKRFGQNFLTDGNVIDRIVGAISPDNHHVMVEIGPGLGALTEPVAEAVDNLTVVELDRDLVERLHHHPVLKDKLTIHQGDALQFDFGQLSVPGKKMKVFGNLPYNISTPLMFHLFEFAEQIETMHFMLQKEVVLRLSASPGCKAYGRLTVMAQYFCQVVPVLEVPPHSFTPAPKVDSAVVRLLPYAVKPFPCKDVTVLRHLCTTAFNMRRKTLRNNLKHMLSDDEFEQLGIDSSQRPEQISVQQYVAMANMVCDKKA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_MESM1
Sequence: MKKINLKDKEIEKIINNEQQRQEEHIELIASENYVSKDVLEATGSILTNKYSEGYPGARYYDGCEFVDQIETLAIERLKKLFNVKFANVQPHSGSSANSAAIAALVKPGGKILGMSLDAGGHLTHGYKISFSGTFYDPYFYGVNDEGLLDYDVIEKLAEKIKPELIICGASNYSRTIDFEKFSKIAKKVGAFLLADIAHIAGLIIADLHPSPVGHADVITSTTHKTIRGARGGIIMSNDETLMKKIDRWVFPGYQGGPLVHVIAGKAVAFGEALTPQFKKYQQQIISNAKAFSEEFKKVGTKIISGQTDNHLFTIDVKSSFNISGKEASELMHSINITANKNSIPNDTLGPKISSGVRMGTPAMTTRGFKEVEFKKLARIIIELLANSTSSNLESLKLKLKNEVLELTKAFPTKDYYL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
Protein: PDXT_BREBN
Sequence: MKIGVLALQGAVAEHLRMLEEVGATAVPVKRVEELDDLDGLVIPGGESTTISKLMHKYGFMEAVQEFGKANKPIFGTCAGAILLAKRIQGQDDYHLGLMDIKVERNAFGRQKESFEVLMPVADVGADYPAVFIRAPYIMEVGENGQVLAKHEDKIVVARSGHYLAAAFHPELTEDTRLHKYFLDMVKEYRS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DOF2_ORYSJ
Sequence: MDAAHWHQGLGLVKPMEEMLMGANPNPNGSSNQPPPPPSSAASAQRPIAPPAAGAAAGAGAAGAGAGTERRARPQKEKALNCPRCNSTNTKFCYYNNYSLQQPRYFCKTCRRYWTEGGSLRNVPVGGGSRKNKRSSSSVVPSAAASASTSAAVSGSVPVGLAAKNPKLMHEGAQDLNLAFPHHHGRALQPPEFTAFPSLESSSVCNPGGNLAAANGAGGRGSVGAFSAMELLRSTGCYVPLPQMAPLGMPAEYAAAGFHLGEFRMPPPPQQQQQQQAQTVLGFSLDTHGAGAGGGSGVFGACSAGLQESAAGRLLFPFEDLKPVVSAAAGDANSGGDHQYDHGKNQGGGGGVIGGHEAPGFWNSSMIGNGSSNGGGGGGSW
What is the function of this protein?
Transcription factor that may transactivate seed storage protein genes in developing seeds.
What are the official names of this protein?
Dof zinc finger protein 2, OsDof2.
What are the subcellular locations of this protein?
Nucleus.
Protein: TBCD8_HUMAN
Sequence: MWLKPEEVLLKNALKLWVTQKSSCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVAPFRILLQVPGSQVYSPIACGATLEEINQHWDWLEQNLLHTLSVFDNKDDIASFVKGKVKALIAEETSSRLAEQEEEPEKFREALVKFEARFNFPEAEKLVTYYSCCCWKGRVPRQGWLYLSINHLCFYSFFLGKELKLVVPWVDIQKLERTSNVFLTDTIRITTQNKERDFSMFLNLDEVFKVMEQLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGCCKIILPLREVVSIEKMEDTSLLPHPIIVSIRSKVAFQFIELRDRDSLVEALLARLKQVHANHPVHYDTSADDDMASLVFHSTSMCSDHRFGDLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSREQIKISLWNDHFVEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSMNILTSVLLLYTKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFEELIKGHLPELAEHMNDLSALASVSLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLEANAEDLCSSKDDGQALMILSRFLDHIKNEDSPGPPVGSHHAFFSDDQEPYPVTDISDLIRDSYEKFGDQSVEQIEHLRYKHRIRVLQGHEDTTKQNVLRVVIPEVSILPEDLEELYDLFKREHMMSCYWEQPRPMASRHDPSRPYAEQYRIDARQFAHLFQLVSPWTCGAHTEILAERTFRLLDDNMDQLIEFKAFVSCLDIMYNGEMNEKIKLLYRLHIPPALTENDRDSQSPLRNPLLSTSRPLVFGKPNGDAVDYQKQLKQMIKDLAKEKDKTEKELPKMSQREFIQFCKTLYSMFHEDPEENDLYQAIATVTTLLLQIGEVGQRGSSSGSCSQECGEELRASAPSPEDSVFADTGKTPQDSQAFPEAAERDWTVSLEHILASLLTEQSLVNFFEKPLDMKSKLENAKINQYNLKTFEMSHQSQSELKLSNL
What is the function of this protein?
May act as a GTPase-activating protein for Rab family protein(s).
What are the official names of this protein?
TBC1 domain family member 8, AD 3, Vascular Rab-GAP/TBC-containing protein.
Protein: RS10_KORVE
Sequence: MIGKERIRIRLKAYDYRVLDQSTGEIVDTARRTGAQIAGPIPLPTVKNKYCVLRSPHVDKKSREAFEIRTHKRLLDILEPTQQTVDALMKLDLPAGVDVEIKAFGKEHK
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PURT_SULNB
Sequence: MTFTAPLQKDAIRIMLLGSGELGKEVAIEAQRLGIEVIAVDKYENAPAHLVANRSYAIDMQDKSAVLELIEKEQPSYILPEVEAISISALFEAEKRGFHVIPNAEAVNKTMNRKNIRVFAAETLDLKTSGYEFVTTLDGLKAAGERIGFPCVIKPVMSSSGHGQSIAKTANDIERSWEIAKEARGDASELIVEEFVPFDYEITLLTVRNETGTTFCEPIGHVQKDGDFILSWQPMQMSPEALKKAQEIAKAVTDGLGGRGIFGVEFFVKDEEVYFSELSPRPHDTGMVTLITQSQSEFALHVRAVLGLPLDFTFYGAGACGAYKAKNESHNPVLEIPDDAFTKDSFVRVFGKPESHVGRRMAVSLVLDEVKEAKRRATEIVETIDDH
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: TX311_LYCSI
Sequence: MKFVLLFGVLLVTLFSYSSAEMLDDFDQAVEDELLSLIEKEEARAKECTPRFYDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVCTCQQPKHLKYMEKAADKAKKFGGKIKKWFG
What are the official names of this protein?
U3-lycotoxin-Ls1a, Toxin-like structure LSTX-B11.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS12_NANEQ
Sequence: MVPNGLFAGRKLKKIRKKFRWNDYRYVRRMLRIKEKYDPLEGAPMASGIVLEKTDVERRQPNSGRIKVVRVQLKKNGKVVTAFTPGDGAIKVIDEHDEVLIVGIRGRQGRSMGDIPGVRYKVYLVNGQPLELLRKGKIEKARR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS17_LACGA
Sequence: MSETNERNNRHVYQGRVVSDKMDKTITVVVDTYKNHPVYKKRIKYSKKYYAHDENNEAKIGDTVRIMETRPLSHAKRYRLTKIVKKSI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: GLO2_SALG2
Sequence: MNLNSIPAFQDNYIWVLTNDEGRCVIVDPGEAAPVLKAIAEHKWMPEAIFLTHHHHDHVGGVKELLQHFPQMTVYGPAETKDKGATHLVGDGDTIRVLGEKFTLFATPGHTLGHVCYFSHPYLFCGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTLICCAHEYTLANIKFALSILPHDSFINEYYRKVKELRVKKQMTLPVILKNERKINLFLRTEDIDLINEINKETILQQPEARFAWLRSKKDTF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: RL10_NITHX
Sequence: MERAAKKEAVEALNEVFKTTGVAVVAHYSGLTVAQMQKLRMQMKQAGASVKVSKNRLAKIALEGTDVVAIGSLLKGPTVIATSNDPVAAPKVAVEFAKTNESFVILGGSMGKTVLNVDSVKALASLPSLDELRGKLVGLLVAPATKIAQLSTAPAAKLARVVQAYASKSEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: COBQ_SALPK
Sequence: MTQAVMLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMALNSGITPDGKEMGRAQIFQAEAAGITPDVRMNPVLLKPTSDRQAQVVLMGKVATNMDAVSYHDYKPRLREQILAVYNSLAQEYDVIVLEGAGSPAEINLRDRDIVNMGMAEMAQCPVILVADIDRGGVFAAIYGTLALLHKQERDRVKGVIINKFRGDVALLYSGIEQIESLTGVPVLGVMPWLDVDLEDEDGVALQNDKYRGNAPRDITIAIVQLPHISNFTDFNALAAQPDVRIRYIRRPEALTDADLVILPGSKNTLSDLAWLRESGMADAVLQTHRQGVPVMGICGGYQMLGDTIVDEVESGLGTQPGLGLLNTITRFAQDKTTTQVNATMSGELPGWLAAAAGLPVRGYEIHMGETVLQEGCCTAMTLQKNGCSVADGAVTADGLAFGTYLHGLFDSDAFTRAVVNGLRARKGLAPWETTFCYAEHKARQFDLLAEAMRQHIDIDKIYTIMQQHQEPV
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: GMHA_SALTI
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVSNDFGYDYIFSRYVEAVGREGDVLLGISTSGNSGNVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWP16_PHAVU
Sequence: DVNGGGHTLPQPLYQTTVVL
What are the official names of this protein?
36 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PKN1_CHLPN
Sequence: MESEKDIGAKFLGDYRILYRKGQSLWSEDLLAEHRFIKKRYLIRLLLPDLGSSQPFMEAFHDVVVKLAKLNHPGILSIENVSESEGRCFLVTQEQDIPILSLTQYLKSIPRKLTELEIVDIVSQLASLLDYVHSEGLAQEEWNLDSVYIHILNGVPKVILPDLGFASLIKERILDGFISDEENRESKIKERVLLHTSEGKQGREDTYAFGAITYYLLFGFLPQGIFPMPSKVFSDFIYDWDFLISSCLSCFMEERAKELFPLIRKKTLGEELQNVVTNCIESSLREVPDPLESSQNLPQAVLKVGETKVSHQQKESAEHLEFVLVEACSIDEAMDTAIESESSSGVEEEGYSLALQSLLVREPVVSRYVEAEKEEPKPQPILTEMVLIEGGEFSRGSVEGQRDELPVHKVILHSFFLDVHPVTNEQFIRYLECCGSEQDKYYNELIRLRDSRIQRRSGRLVIEPGYAKHPVVGVTWYGASGYAEWIGKRLPTEAEWEIAASGGVAALRYPCGEEIEKSRANFFTADTTTVMSYPPNPYGLYDMAGNVYEWCQDWYGYDFYEISAQEPESPQGPAQGVYRVLRGGCWKSLKDDLRCAHRHRNNPGAVNSTYGFRCAKNIN
What is the function of this protein?
Together with the serine/threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth.
What are the official names of this protein?
Serine/threonine-protein kinase pkn1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: CHLI_ORYSI
Sequence: MASAFSPATAAPAASPALFSASTSRPLSLTAAAAAVSARIPSRRGFRRGRFTVCNVAAPSATQQEAKAAGAKESLRPVYPFAAIVGQDEMKLCLLLNVIDPKIGGVMIMGDRGTGKSTTVRSLVDLLPDIRVVVGDPFNSDPDDPEVMGPEVRERVLEGEKLPVVTAKITMVDLPLGATEDRVCGTIDIEKALTDGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISISHPARFILIGSGNPEEGELRPQLLDRFGMHAQVGTVRDAELRVKIVEERARFDRDPKAFRESYLEEQDKLQQQISSARSNLGAVQIDHDLRVKISKVCAELNVDGLRGDIVTNRAAKALAALKGRDTVTVEDIATVIPNCLRHRLRKDPLESIDSGLLVVEKFYEVFT
What is the function of this protein?
Involved in chlorophyll biosynthesis.  Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.  The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step (By similarity).
What are the official names of this protein?
Magnesium-chelatase subunit ChlI, chloroplastic, Mg-chelatase subunit I, Mg-protoporphyrin IX chelatase subunit ChlI, Protein CHLORINA 9.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMF_YERPG
Sequence: MLSYAPENAYQRASTMENKKVFPKEKSGLHPRNRHRSRYDFDALSVSCPELIPFLTPTAYGDISVDFADPLAVKMLNKALLKHFYGIEYWDIPADSLCPPIPGRADYVHHLADLLASCNGEVIPKGKNIALLDIGVGANCIYPIIGQREYGWRFTGTDIDSHALSAAKMVVSMNPTLKNTLRLKQQKDPHAIFEGVWAVNERYDATLCNPPFHGSAEEAAATTRRKLHKLGKNEVAAKPVQNFGGKNSELWCEGGEEGFVSRMVAESVAKAQNCFWFTSLISKKTTLPAIYHALRYVKAVEVRTIEMAQGQKVSRFVAWTFLTPEQQAAWVAERWA
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_ECOL6
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RPFC_XANC8
Sequence: MKSPLPWLKRRLSGRADSEHAQNLIRIIITTLFISYLGWRYQHTHGDTLMATWLILVGELLVSLGLMVAILLRPQVSHTRRLIGMLLDYTCTGAIMAIQGEPASPLYAVCMWVTIGNGLRYGSNYLRAATAMGSLCFLGAILISPYWKANPYLSWGLLLGLIAVPLYFDSLLRAMTRAVREARHANQAKSRFLANMSHEFRTPLNGLSGMTEVLATTRLDAEQKECLNTIQASARSLLSLVEEVLDISAIEAGKIRIDRRDFSLREMIGSVNLILQPQARGRRLEYGTQVADDVPDLLKGDTAHLRQVLLNLVGNAVKFTEHGHVLLRVTRVSGSAEDAVRLRFDVEDTGIGVPMDMRPRLFEAFEQADVGLSRRYEGTGLGTTIAKGLVEAMGGSIGFKENQPSGSVFWFELPMAIGEPLKSSTVRVPTGALVDAPEELESSNIIAFSNPFLRHRARVRSMRMLVADDHEANRMVLQRLLEKAGHKVLCVNGAEQVLDAMAEEDYDAVIVDLHMPGMNGLDMLKQLRVMQASGMRYTPVVVLSADVTPEAIRACEQAGARAFLAKPVLAAKLLDTLADLAVSTRQLATPATTVQVATSFEGVLDSSVLDELAALGMGEEFERQFVRQCLDDAQNCVGDIERDGTCSDWEQLRESAHALRGVASNLGLAQVASSGGELMRMADWQLQAEWRLRLSTLREQLKAGKDALDARVQGVKDGECSPRSNE
What is the function of this protein?
Hybrid sensor kinase that regulates diverse biological functions through two distinct molecular mechanisms (PubMed:16940295).  At low cell density, the extracellular concentration of the diffusible signaling factor (DSF) is below a threshold, and unphosphorylated RpfC is involved in the negative regulation of DSF synthesis, via direct interaction with the DSF synthase RpfF.  Interaction prevents synthesis of DSF, which remains at a basal level.  This activity does not involve the phosphorelay mechanism and is not dependent on RpfG (PubMed:11123673, PubMed:16940295).  Is also member of the two-component regulatory system RpfG/RpfC, which is involved in the perception and response to DSF, which is essential for cell-cell signaling (PubMed:11123673, PubMed:12960398).  At high cell density, the level of extracellular DSF increases and binding of DSF to the sensor region of RpfC causes autophosphorylation of RpfC, which results in the release of RpfF and the activation of RpfG via a four-step phosphorelay (PubMed:16940295, PubMed:28369120).  Activation of RpfG leads to the positive regulation of biofilm dispersal and the production of virulence factors (PubMed:12960398).
What are the official names of this protein?
Sensory/regulatory protein RpfC.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes at the cell poles.
Protein: CP240_MOUSE
Sequence: MDPFVVLVLCLSFLLVLSLWRQRSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEEFSGRGRIPVFDKVSTGKGIGFSHGNVWKATRVFTVNTLRNLGMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGSHNKLFKNHTWIKSYLLGKIKEHEESLDVTNPRDFIDYFLIQRRQKNGIEHMDYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRNHMPYTNAMVHEVQRYIDLGPNGVVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPKHSGFSKIPPNFQMCFIPVE
What is the function of this protein?
A cytochrome P450 monooxygenase that may play a major role in the metabolism of arachidonic acid in the intestinal tract (PubMed:10908295, PubMed:9721182).  Exhibits regioselective hydroxylase and epoxidase activity toward arachidonic acid, producing 16(R)-hydroxyeicosatetraenoic acid (HETE) and (14R,15S)-epoxyeicosatrienoic acid (EpETrE) as major products (PubMed:10908295).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:10908295).
What are the official names of this protein?
Cytochrome P450 2C40, CYPIIC40.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: VIP_MOUSE
Sequence: MEARSKPQFLAFLILFSVLFSQSLAWPLFGPPSVVRLDDRMPFEGAGDPDQVSLKADSDILQNPLAENGTPYYDVSRNARHADGVFTSDYSRLLGQISAKKYLESLIGKRISSSISEDPVPIKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSEGDSADFLEELEK
What is the function of this protein?
PHM-27 is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin (By similarity).  PHM also causes vasodilation.
What are the official names of this protein?
VIP peptides.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.