PharMolix/UniProtQA huggingface dataset:
Protein: UL49_EHV2
Sequence: MDPVRFPEIFHRLGGGGGGGGDLLGGGEADGLMRALCEGLRVGEEDCARFVLYGVAYWQGGRCPEWVAHITRCADLSCFATYLLTCHRSGGCEFTGGRVARDRLPSLRESVEVLQSLFLAFTLVIFKSMRVGVEAAGGAFRRMARDVHWNLLLTLGLDKAAPAFMAAAGLGEYSLPLVRCNNNMLNVLVGMKRKSRNHFQNDTPLSVPAPHLRLEPRCMFLREGRAEAPLSDHDLSFLKALRDGGRTVPCGNPFNAMVGALAFQSMAASRYVVLPNTTDIKSFTAHDLYSKIIGYNILCPFLSVPVHRGYRGGDGAGARLAVVCAECGYCLNLGKGKFSKVSFNPTHIFYCRDQKEKYLTTCASTGRIYCSFCGSCRIRTYPLKFTVGNRQYIRAVGASNCSIVVSDSATELDLVLPCLGDDCTQVLLRRVAVCDLFYLTELGPGLYCSRCLKPTS
What are the official names of this protein?
Uncharacterized gene 66 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL49 family.
Protein: TRX1_HHV11
Sequence: MKTNPLPATPSVWGGSTVELPPTTRDTAGQGLLRRVLRPPISRRDGPGLPRGSGPRRAASTLWLLGLDGTDAPPGALTPNDDTEQALDKILRGTMRGGAALIGSPRHHLTRQVILTDLCQPNADRAGTLLLALRHPADLPHLAHQRAPPGRQTERLGEAWGQLMEATALGSGRAESGCTRAGLVSFNFLVAACAASYDARDAADAVRAHVTANYRGTRVGARLDRFSECLRAMVHTHVFPHEVMRFFGGLVSWVTQDELASVTAVCAGPQEAAHTGHPGRPRSAVILPACAFVDLDAELGLGGPGAAFLYLVFTYRQRRDQELCCVYVIKSQLPPRGLEPALERLFGRLRITNTIHGTEDMTPPAPNRNPDFPLAGLAANPQTPRCSAGQVTNPQFADRLYRWQPDLRGRPTARTCTYAAFAELGMMPEDSPRCLHRTERFGAVSVPVVILEGVVWRPGEWRACA
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ODBB_THET2
Sequence: MALMTMVQALNRALDEEMAKDPRVVVLGEDVGKRGGVFLVTEGLLQKYGPDRVMDTPLSEAAIVGAALGMAAHGLRPVAEIQFADYIFPGFDQLVSQVAKLRYRSGGQFTAPLVVRMPSGGGVRGGHHHSQSPEAHFVHTAGLKVVAVSTPYDAKGLLKAAIRDEDPVVFLEPKRLYRSVKEEVPEEDYTLSIGKAALRREGKDLTLIGYGTVMPEVLQAAAELAKAGVSAEVLDLRTLMPWDYEAVMNSVAKTGRVVLVSDAPRHASFVSEVAATIAEDLLDMLLAPPIRVTGFDTPYPYAQDKLYLPTVTRILNAAKRALDY
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
2-oxoisovalerate dehydrogenase subunit beta, Branched-chain alpha-keto acid dehydrogenase E1 component beta chain, BCKDH E1-beta.
Protein: PFL_LACLM
Sequence: MKTEVTENIFEQAWDGFKGTNWRDKASVTRFVQENYKPYDGDESFLAGPTERTLKVKKIIEDTKNHYEEVGFPFDTDRVTSIDKIPAGYIDANDKELELIYGMQNSELFRLNFMPRGGLRVAEKILTEHGLSVDPGLHDVLSQTMTSVNDGIFRAYTSAIRKARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMKEKAKEWDAITEINDDNIRLKEEINMQYQALQEVVNFGALYGLDVSRPAMNVKEAIQWVNIAYMAVCRVINGAATSLGRVPIVLDIFAERDLARGTFTEQEIQEFVDDFILKLRTMKFARAAAYDELYSGDPTFITTSMAGMGNDGRHRVTKMDYRFLNTLDTIGNAPEPNLTVLWDSKLPYSFKRYSMSMSHKHSSIQYEGVETMAKDGYGEMSCISCCVSPLDPENEEGRHNLQYFGARVNVLKAMLTGLNGGYDDVHKDYKVFDIEPVRDEILDYDTVMENFDKSLNWLTDTYVDAMNIIHYMTDKYNYEAVQMAFLPTKVRANMGFGICGFANTVDSLSAIKYAKVKTLRDENGYIYDYEVEGDFPRYGEDDDRADDIAKLVMKMYHEKLASHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHKGVFLNEDGTVNKSKLEFFSPGANPSNKAKGGWLQNLRSLAKLEFKDANDGISLTTQVSPRALGKTRDEQVDNLVQILDGYFTPGALINGTEFAGQHVNLNVMDLKDVYDKIMRGEDVIVRISGYCVNTKYLTPEQKQELTERVFHEVLSNDDEEVMHTSNI
What are the official names of this protein?
Formate acetyltransferase, Pyruvate formate-lyase.
What is the protein family that this protein belongs to?
Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_CAMJD
Sequence: MNKIFAAFKPRGLSSNSFLSTLKKKYKNKKAGYSGTLDPFAKGVLIVAFGQYAKLFRFLKKTPKTYKATLWLGVYSLSLDDQNIKKIQNIKEFDLAILKQIIDQMQGIISYTPPQFSAKRINGTRAYELAKKGIEANLKPCQMEVFDCKILSYNHPFLNIEITVSEGAYIRSYCELFARKLGINATLSSLERIKEGKFVYNNEKSLNVLKYINLKPNFIKDLNKLENGAKIFVEELEFHDEGDYYIETEKYFSIINIKENTVKYLLNKVEKC
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: XERS_STRSY
Sequence: MRRELLLEKIDQLKEIMPWFVLEYYQSKLAVPYSFTTLYEYLKEYRRFFEWLQDSDLVAVERIADIPLDVLEHLTKKDMEAFILYLRERPLLNANTTQNGVSQTTINRTLSALSSLFKYLTEEVENEQGEPYFYRNVMKKVSTKKKKETLAARAENIKQKLFLGDETMEFLDYVDKEYQVNLSKRALSSFQKNKERDLAILALLLASGVRLSEAVNLDLRDVNLNMMIIEVTRKGGKRDSVNVAGFAKPYLEAYMGIRQQRYKAEKTDTAFFLSEYRGLPNRIDASSIEKMVAKYSADFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHANTQVTDLYTHIVNDEQKNALDQL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPD_CYPCA
Sequence: MHTVKLLCVVFSCLCAVAWASSNRQPCHSPPLTSGTMKVVSTGGHDLASGEFSYDSKANKFRFVEDTAHANKTSHMDVLVHFEEGVLYEIDSKNESCKKETLQFRKHLMEIPPDATHESEIYMGSPSITEQGLRVRVWNGKLPELHAHYSLSTTSCGCLPVSGSYYGDKKDLLFSFFGVETEVDDPQVFVPPAYCEAVAFEEAPDDHSFFDLFHD
What is the function of this protein?
May play a role in neural plasticity.  May be involved during axon regeneration.
What are the official names of this protein?
Ependymin, EPD.
What is the protein family that this protein belongs to?
Belongs to the ependymin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GID8_HUMAN
Sequence: MSYAEKPDEITKDEWMEKLNNLHVQRADMNRLIMNYLVTEGFKEAAEKFRMESGIEPSVDLETLDERIKIREMILKGQIQEAIALINSLHPELLDTNRYLYFHLQQQHLIELIRQRETEAALEFAQTQLAEQGEESRECLTEMERTLALLAFDSPEESPFGDLLHTMQRQKVWSEVNQAVLDYENRESTPKLAKLLKLLLWAQNELDQKKVKYPKMTDLSKGVIEEPK
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (PubMed:29911972).  Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation (PubMed:28829046).
What are the official names of this protein?
Glucose-induced degradation protein 8 homolog, Two hybrid-associated protein 1 with RanBPM, Twa1.
What is the protein family that this protein belongs to?
Belongs to the GID8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in the cytoplasm in the absence of Wnt stimulation and in the nucleus in the presence of Wnt stimulation.
Protein: NST1_LODEL
Sequence: MSNRGNLNLNLPPSSGKYTVGENVHFELSKEKNNSTNSNPHTSSTSTSNSNNTGIGVAKSLSTNDNNNDNDNQQPQQHEQIQSKAKSQSQSQSQSQSQPQTQVQVEQQQQQQSLVNSPAAQLAAKKRKKKKSKKSSNNNGNNSNTNSNSNSEITNTSISMPHAFLNNPDEDYPTSRVIKQAPNGDVIVESLDHVGGTYEDHLHDDYSDEDTLHHHLRQAPHQASNNNHIHNHSHTSSHPLQHTPNHLHHASHNANPLTQHISASGASMRSHGHNDAHSNLWDSASLEEQEKLKEFWESLEESQKLDLVKIDKQSIMKMFKNETRQHLQQLLQNGVLNNQNASSSNNCACKYCGRRNNIIEEELENIYDNHFDDIIDFIHEVRDINDLNALPGLLFGGFHMLEEERRLQKRKQLHNEHLELAKSSNLQNQAHIEEIRAQMDKLKMNQRQQSQSQSQSQSQQQRDVQTAQSQVLSKDSSLKNANTSMNKQHTSQQLLQPQIQAQGKNNLQQNHHTHHHHQQPLQHPTVQISATFLSSNPTETQLFNKLLDPKLFEALESLDLQKMKEVSHFDPQNTAHINMLEKAGSLREIVRDLHNVDRNHLEKGMSYVQNMGKLFSNIASLNPSNPEDAEKIMTGQLNEQFNQGLSTFAEDLLKNDGSSFISMMETLSELRSAREELLKEKTPYNGLLTKTPAATSQDREQQVQPNHSHWLDEDDHDHEHEHEHEHEHEHEIDDEDHEHYCCHHHQHHHLHGDEEYDEEDEEDDEEYEYGDDEEEEDEEDEEEGEDEELEEVVEDDVDEEILDDEEEFDAKNASDTESEISEEEKMQEIRRLFLIQVIKLFQERLKSAYKEKVSKDNTRKLFEELEAEEAAKREKEAKKLKQKEKAKERKRLQQLAKEEEKRKKEEEAKRIAEELHAKQEQLKLEQKKKKEEARLRREEEKKKKLEEIKRREAEHKRKVEEQIKHDEEQRRLKEERRKELEEKKRQKEEEKKQKELLKKQKEEEKERLRIEREKQLEKEAAVSKSIPQPSPKSKHVMKLAATFQSDIPSKQNQAQNGNQSHLPPQSRLRQDEENPQKTFANSVFSAKEYNSIYQPLPGSLSNNSSSAALSVGTQLSNFQALSHPQQQQQQYSNDIYLPSANLATATVQSPRSAPINLPNGTSAVGVSLANHLSLNNSSQGSPWTTNSTLSSNLGSTGLSHGQGQTVSGVNTNLPSSIGITSGGASQIFQPQPQPQLQPHQPQQQQQQQQQQQQQQQQNYFSPFNSFSEPLVGEPFQGIVHPTTNINNSTTASSSTGAIIPPMNPSGNIWNSNIGATATNAPASVSRNNSVWSNNAITPKPSEPSFLSTAGRSSSLWGTLANAPVASSSNNNSNATANYDNNNVRSLGSSSFAPANPGQHELEVIQTAIYNCFQMMQNSNQLEFNVAPLMAIFSNVRSLTNKTQLTVNQFLNCCVSNSLYQFDFVYDDFGTVTHLKVGLNGLNDHNSVNGFSKSSTTPPLLPISAMNSKILGYTQQQQQQQQPQPQPQSQQQYPLQHSHQQRLLQLFSNNQTILSQDVTSSAFATGTNTQGSSYGQVQLGAVSPAFARTSPPGLFPNDIPLLSTINELNSTPSTGTGTGTGSGVGAGTGAVFGSGIWN
What is the function of this protein?
May act as a negative regulator of salt tolerance.
What are the official names of this protein?
Stress response protein NST1.
What is the protein family that this protein belongs to?
Belongs to the NST1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_BORHD
Sequence: MAVPKFKPSKSRSRTRRSINMRKKIPQLQECSNCGYLVIRHRVCLKCGYYKNIQYLELGL
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ORCO_DROME
Sequence: MTTSMQPSKYTGLVADLMPNIRAMKYSGLFMHNFTGGSAFMKKVYSSVHLVFLLMQFTFILVNMALNAEEVNELSGNTITTLFFTHCITKFIYLAVNQKNFYRTLNIWNQVNTHPLFAESDARYHSIALAKMRKLFFLVMLTTVASATAWTTITFFGDSVKMVVDHETNSSIPVEIPRLPIKSFYPWNASHGMFYMISFAFQIYYVLFSMIHSNLCDVMFCSWLIFACEQLQHLKGIMKPLMELSASLDTYRPNSAALFRSLSANSKSELIHNEEKDPGTDMDMSGIYSSKADWGAQFRAPSTLQSFGGNGGGGNGLVNGANPNGLTKKQEMMVRSAIKYWVERHKHVVRLVAAIGDTYGAALLLHMLTSTIKLTLLAYQATKINGVNVYAFTVVGYLGYALAQVFHFCIFGNRLIEESSSVMEAAYSCHWYDGSEEAKTFVQIVCQQCQKAMSISGAKFFTVSLDLFASVLGAVVTYFMVLVQLK
What is the function of this protein?
Odorant coreceptor which complexes with conventional odorant receptors (ORs) to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Orco is a universal and integral part of the functional odorant receptor, involved in the dendritic localization of other olfactory receptors.  Expression of Orco alone leads to formation of rapid and transient ion channels not directly responding to odorants, but directly activated by intracellular cAMP or cGMP.  Snmp, Or67d and lush act in concert to capture fatty-acid-derived male pheromone 11-cis vaccenyl acetate (cVA) molecules on the surface of Or67d expressing olfactory dendrites and facilitate their transfer to the odorant-receptor Orco complex.
What are the official names of this protein?
Odorant receptor coreceptor, Odorant receptor 83b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Orco subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPB_POLAQ
Sequence: MSNGNIVQCIGPVVDIQFPRDKMPNIYDALTLVESGEKSFAEKGLTFEVQQQIGDGVVRAIAMGASDGLRRGMEVKSTGKPISVPVGPATLGRIMDVLGRPIDDAGPIATEERRAIHQPAPKFDELSPSVDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMKESNVIDKVAMVFGQMNEPPGNRLRVALTGLTMAEAFRDEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSVTSIQAVYVPADDLTDPSPATTFLHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQVVGQEHYEVARDVQMTLQRYKELRDIIAILGMDELSPEDKLAVSRARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMICSGELDHLPEQAFYMVGSIDEAIEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNPA_MYCPA
Sequence: MLPARNRMTRSTEFDATVKHGTRMAQPDIVVHLRRGSEPDDESAGPRVGLVVGKAVGTAVQRHRVARRLRHVARPLLGELQPSDRLVIRALPGSRTVSSARLAQELQRCLRRMPAGSGR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: COQ4_LEIBR
Sequence: MKNCMMADQRGRSILKHQPVVGDEVLEFSRGLAPSTFGFRYAAYMDRNHFLPSGRAAVKHIADPTLAYVMMRHRQCHDFLHVITGCGRSVEEELAVKVFEWKHTGLPLGLLSLLGGASRLSATQLAHMRLFWEWASHNAPCSRHDKPAVPMYLNVPWEDMLAKEYDEVAAYTGITPLPVFLKKHQKQ
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PUR5_SODGM
Sequence: MTDKTSLSYKDAGVDIDAGNALVDRIKGVVKQTKRPEVMGGLGGFGALCALPQKYREPILVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTAAAVITGIAEGCKQSGCALVGGETAEMPGMYHGEDYDVAGFCVGVVEKADIIDGSKVQAGDTLLALAASGPHSNGYSLVRKILSFSQTDPEQTQVEGKSLADHLLAPTCIYVKALLSLIAQTEVHAIAHLTGGGFWENIPRVLPAGTQAVIDKNSWQWPAVFRWLQQAGNVSRHEMYRTFNCGVGMVIAVPADSTAKALAILADLGETAWVLGQIHPADGEHQVIIR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEBP_DROVI
Sequence: MLNMESPQMYADAVQTLAHVDLKKQPQPLPQQATIGQITLTAMSSAQQQQQQQQQQQQQQQQQQQQQQQVTTDANNNATVQDAALLVKQHAMQQMQLSNNNSNNLLQKQMLQQYSTQTDLDELTTQEITLDLQHLIDDQFRDTETLGIFSDMVTSPGGLSATLPPSGMVSAAAKVLQQQQQTLANARQQQHSYGRAALAYMRQAVHSNATYNNHSSDENSSVGSDSSSTIKEEPIDPDYRRHLQESVTGQAAAAFINNSNGLYNAYQSNNLSNNNSSSNNSSNNSSNNSSNSNTNSTNAAQFTNLTTANVLAHHSLPHLTANTAQQLLKHHSKLQQTQQQHAQQQQQHAQQQHRKHSNKHVDKGTEEYRRRRERNNIAVRKSREKAKVRSKEVEERVKSLLKEKDALLRQLSEMTNELSLHKQIYMQLMNHTNPEVSRVCRSFLNTNEHAL
What is the function of this protein?
May be required for the expression of gene products mediating border cell migration.  Among the DNA sequences that this protein binds with high affinity is a conserved site within the promoter of its gene.
What are the official names of this protein?
CCAAT/enhancer-binding protein, C/EBP, Slow border cell protein.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. C/EBP subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: BAR1_YEAST
Sequence: MSAINHLCLKLILASFAIINTITALTNDGTGHLEFLLQHEEEMYYATTLDIGTPSQSLTVLFDTGSADFWVMDSSNPFCLPNSNTSSYSNATYNGEEVKPSIDCRSMSTYNEHRSSTYQYLENGRFYITYADGTFADGSWGTETVSINGIDIPNIQFGVAKYATTPVSGVLGIGFPRRESVKGYEGAPNEYYPNFPQILKSEKIIDVVAYSLFLNSPDSGTGSIVFGAIDESKFSGDLFTFPMVNEYPTIVDAPATLAMTIQGLGAQNKSSCEHETFTTTKYPVLLDSGTSLLNAPKVIADKMASFVNASYSEEEGIYILDCPVSVGDVEYNFDFGDLQISVPLSSLILSPETEGSYCGFAVQPTNDSMVLGDVFLSSAYVVFDLDNYKISLAQANWNASEVSKKLVNIQTDGSISGAKIATAEPWSTNEPFTVTSDIYSSTGCKSRPFLQSSTASSLIAETNVQSRNCSTKMPGTRSTTVLSKPTQNSAMHQSTGAVTQTSNETKLELSSTMANSGSVSLPTSNSIDKEFEHSKSQTTSDPSVAEHSTFNQTFVHETKYRPTHKTVITETVTKYSTVLINVCKPTY
What is the function of this protein?
This protein called 'barrier activity' is excreted by yeast cells mating type a.  It is probably a protease that cleaves alpha-factor and thus acts as an antagonist of this mating pheromone and establishes optimal pheromone concentration for conjugation.
What are the official names of this protein?
Barrierpepsin, BAR proteinase, Extracellular 'barrier' protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PERT_BORBR
Sequence: MNMSLSRIVKAAPLRRTTLAMALGALGALGAAPAAHADWNNQSIIKAGERQHGIHIKQSDGAGVRTATGTTIKVSGRQAQGVLLENPAAELRFQNGSVTSSGQLFDEGVRRFLGTVTVKAGKLVADHATLANVSDTRDDDGIALYVAGEQAQASIADSTLQGAGGVRVERGANVTVQRSTIVDGGLHIGTLQPLQPEDLPPSRVVLGDTSVTAVPASGAPAAVSVFGANELTVDGGHITGGRAAGVAAMDGAIVHLQRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPLLDGWYGVDVSDSTVDLAQSIVEAPQLGAAIRAGRGARVTVSGGSLSAPHGNVIETGGGARRFPPPASPLSITLQAGARAQGRALLYRVLPEPVKLTLAGGAQGQGDIVATELPPIPGASSGPLDVALASQARWTGATRAVDSLSIDNATWVMTDNSNVGALRLASDGSVDFQQPAEAGRFKVLMVDTLAGSGLFRMNVFADLGLSDKLVVMRDASGQHRLWVRNSGSEPASANTMLLVQTPRGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQRQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYIANSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFAHADGWFLEPQAELAVFRVGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVRTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW
What is the function of this protein?
Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence.  Pertactin may have a role in bacterial adhesion, and thus play a role in virulence.  May contribute to the disease state of whooping cough.
What are the official names of this protein?
Pertactin autotransporter, P.94.
What are the subcellular locations of this protein?
[Pertactin autotransporter]: Periplasm. SUBCELLULAR LOCATION: [Outer membrane protein P.68]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Pertactin translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: ZN878_HUMAN
Sequence: MDSVAFEDVAVNFTQEEWALLDPSQKNLYREVMQETLRNLTSIGKKWNNQYIEDEHQNPRRNLRRLIGERLSESKESHQHGEVLTQVPDDTLKKKTPGVQSYESSVCGEIGIGLSSLNRHLRAFSYSSSLAIHGRTHTGEKPYECKECGKAFRFPSSVRRHERIHSAKKPYECKQCGKAFSFPSSVRRHERIHSAKKPYECKQCGKALSYLVSFQTHMRMHTGERPHKCNICGKAFFSPSSLKRHEKSHTGEKRYKCKQCDKAFNCPSSFQYHERTHSGEKPYECTQCRKAFRSVKYLRVHERKHTGEKPYECKLCGKGFISSTSFRYHEKTHTGEKPYECKKCVKAFSFVKDLRIHERTHTGEKPFECKQCGKTFTSSNSFHYHERTHTGEKPYECKQCGKAFRSASVLQKHIRTHTGEKPYGCKQCGKVFRVASQLKMHERTHTGEKPYECKQCGKAFISSNSIRYHKRTHTGEKPYKCKQCGKAFISSNSFLYHERIHTGEKPYECKQCGKAFRSASILQKHVRTHAG
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 878.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPJ_PICAN
Sequence: STLNVLRYSSLAAGIVYGAYHTYTLKLEGEKKQELYDYQKKLKLVEAAKAEYRKLNPPKQAASTEAVNLDDPEFDFGKFILGAVEKLGS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169).  F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27791192).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).  Part of the complex F(0) domain (By similarity).  Minor subunit located with subunit a/ATP6 in the membrane (By similarity).  Together with subunit g/ATP20, probably contributes to membrane curvature at the site of the ATP synthase dimer, ultimately contributing to formation of cristae (By similarity).
What are the official names of this protein?
ATP synthase subunit e, mitochondrial, ATPase subunit e, Translocase of the inner membrane protein 11.
What is the protein family that this protein belongs to?
Belongs to the ATPase e subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.
Protein: PYRB_JANMA
Sequence: MFNPQLNKNGELQHLLTIEGLPKANILHILDTASSFVSIGDREVKKVPLMRGKSVFNLFFENSTRTRTTFEIASKRLSADVINLNIQASSSSKGESLLDTIDNLSAMHADMFVVRHAQSGAPYLIAKHLSDTSQSHVHVVNAGDGRHAHPTQGLLDMYTIRHYKKDFSNLTVAIVGDILHSRVARSDIHALTTLGVPEIRAIGPRTLLPSGLEQMGVRVFTDINKGLKDVDVIIMLRLQNERMSGALLPSAQEFFKSYGLTTERLALAKPDAIVMHPGPMNRGVEIESAVADGTQAVILPQVTFGIAVRMAVMSILAGN
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RS7_KLEP3
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAEAIVYSALETLAQRSGKNELEAFEVALDNVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELTDAADNKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MMPL7_MYCTU
Sequence: MPSPAGRLHRIRYIRLKKSSPDCRATITSGSADGQRRSPRLTNLLVVAAWVAAAVIANLLLTFTQAEPHDTSPALLPQDAKTAAATSRIAQAFPGTGSNAIAYLVVEGGSTLEPQDQPYYDAAVGALRADTRHVGSVLDWWSDPVTAPLGTSPDGRSATAMVWLRGEAGTTQAAESLDAVRSVLRQLPPSEGLRASIVVPAITNDMPMQITAWQSATIVTVAAVIAVLLLLRARLSVRAAAIVLLTADLSLAVAWPLAAVVRGHDWGTDSVFSWTLAAVLTIGTITAATMLAARLGSDAGHSAAPTYRDSLPAFALPGACVAIFTGPLLLARTPALHGVGTAGLGVFVALAASLTVLPALIALAGASRQLPAPTTGAGWTGRLSLPVSSASALGTAAVLAICMLPIIGMRWGVAENPTRQGGAQVLPGNALPDVVVIKSARDLRDPAALIAINQVSHRLVEVPGVRKVESAAWPAGVPWTDASLSSAAGRLADQLGQQAGSFVPAVTAIKSMKSIIEQMSGAVDQLDSTVNVTLAGARQAQQYLDPMLAAARNLKNKTTELSEYLETIHTWIVGFTNCPDDVLCTAMRKVIEPYDIVVTGMNELSTGADRISAISTQTMSALSSAPRMVAQMRSALAQVRSFVPKLETTIQDAMPQIAQASAMLKNLSADFADTGEGGFHLSRKDLADPSYRHVRESMFSSDGTATRLFLYSDGQLDLAAAARAQQLEIAAGKAMKYGSLVDSQVTVGGAAQIAAAVRDALIHDAVLLAVILLTVVALASMWRGAVHGAAVGVGVLASYLAALGVSIALWQHLLDRELNALVPLVSFAVLASCGVPYLVAGIKAGRIADEATGARSKGAVSGRGAVAPLAALGGVFGAGLVLVSGGSFSVLSQIGTVVVLGLGVLITVQRAWLPTTPGRR
What is the function of this protein?
Confers a high level of resistance to isoniazid (INH) when overexpressed in M. smegmatis.
What are the official names of this protein?
Phthiocerol dimycocerosate exporter MmpL7.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLSA_MYCMM
Sequence: MAPTSVSNARIEKAVLDAHEKQKNKHGGKNADYIPILAQVPSTLFGVSVATVDGQVFTAGDAGYEFALESISKIFTLALVIEQRGPRELRLKVGADPTGEAFNSVLALELHNDKPMSPLVNAGAISTTSLVDAVGPEDRWRQIVGAQSDFAGRQISISEEINASEQATNFHNRAIAWLLRGSGYIYCDPMEACDIYTRQCSTLVTTADLAVMGATLANGGTNPITGKRVIARKNVPHVLAEMTMEGVYTRSGDWAYTVGLPAKSGVGGGLVAVAPGQLAIAAFSPPLDKVGNSVRAQAAVAQIADTLQLGLFNVPGEEDE
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: URE1_PHODD
Sequence: RISGIGKAGNPDVQPNVDIVIGPGTEVVAGEGKIVTAGGIDTHIHFICPQQAEEGLCSGLTTFIGGGTGPVAGSNATTVTPGVWNMSRMLEAVDDLPINVGLFGKGCVSKPEALREQIEAGAVGLKLHEDWGATPAAINNCMNVADEMDIQVAI
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.