PharMolix/UniProtQA huggingface dataset:
Protein: PME_ASPNG
Sequence: MVKSILASVLFAATALAASRMTAPSGAIVVAKSGGDYDTISAAVDALSTTSTETQTIFIEEGSYDEQVYIPALSGKLIVYGQTEDTTTYTSNLVNITHAIALADVDNDDETATLRNYAEGSAIYNLNIANTCGQACHQALAVSAYASEQGYYACQFTGYQDTLLAETGYQVYAGTYIEGAVDFIFGQHARAWFHECDIRVLEGPSSASITANGRSSESDDSYYVIHKSTVAAADGNDVSSGTYYLGRPWSQYARVCFQKTSMTDVINHLGWTEWSTSTPNTENVTFVEYGNTGTGAEGPRANFSSELTEPITISWLLGSDWEDWVDTSYIN
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.
What are the official names of this protein?
Pectinesterase, PE, Pectin methylesterase.
What is the protein family that this protein belongs to?
Belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted.
Protein: KEFG_SALCH
Sequence: MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQTLASHAKAYGEWLANPVSAGGY
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YO394_YEAST
Sequence: MIVNNTHILTLPPHAVSTLTCILIWHRHTDATVYIISSYPTLTFHSMAHLSLHQY
What are the official names of this protein?
Uncharacterized protein YOR394C-A.
Protein: TSAD_PELPB
Sequence: MNILGIETSCDETSGAVLCSGQVRSNVVSSQRCHAHFGGVVPELASREHERLIVSIVDAAVTEANITKNDLDVIAATAGPGLIGAVMVGLCFAQGMAYALQIPFVPVNHIEAHIFSPFIQEDPFHSSPEGAFVSLTVSGGHTLLSVVEPDLSYSVIGRTLDDAAGEAFDKTGKMLGLPYPAGPVIDKLAEKGDPAFHLFPRALTSKSQTSKNYLGNFDFSFSGLKTSVLTWLQKQSAEFIEHHKADIAASIQYAIVSVLVEKTIAAARSRGIKSVSIAGGVSANSALRRAMKEACKREGITLHVPGTVYSTDNAAMIATLAALKLSRGMKAECCYNIAPYASFAAGSRMA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_METM7
Sequence: MIITIGGLPGTGTTTTSKLISEKYGLNHVCAGFIFRDMAKERNMTLQEFSSYAETNTEVDNEIDRRQVEAAQSGDLILEGRLAGWILKKSDIKPDLSIWLKADPMVRCIRISERENENVDLALEKMISREASEKKRYKEIYNIEIDDLSIYDIVIESSKWDANGVFNIIEKAIENLKA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CADD_NITEU
Sequence: MATNTFKQQVDSIIQSRHLLQHPFYIAWTEGKLTREQLRHYAEQYFYNVLAEPTYLSAVHFNTPHFHNVENSGDISIRQEVLKNLIDEEHGEKNHPALWKAFAFALGADDASLTQADALPETENLVATFRDICINEPFYAGLAALHAFESQVPDIAAVKIDGLAKFYGMKDPDSYEFFSVHQTADIFHSQAEWAIIEKFADTPEKQAEVLAATRRACDALWKFLDGIHENYCANLICEEKTAATLH
What is the function of this protein?
Involved in de novo para-aminobenzoate (PABA) biosynthesis (PubMed:23972426).  Acts as a self-sacrificing or 'suicide' enzyme that utilizes its own active site tyrosine residue(s) as the substrate for PABA synthesis.  The side chain of the tyrosine residue is released from the protein backbone via cleavage of the C(alpha)-C(beta) bond, leaving a glycine in place of the original tyrosine residue.  Reaction requires O(2) and a reduced dimetal cofactor (By similarity).
What are the official names of this protein?
4-aminobenzoate synthase, para-aminobenzoate synthase, PABA synthase.
What is the protein family that this protein belongs to?
Belongs to the CADD family.
Protein: CEFIP_RAT
Sequence: MQGNKKCADGFSDTSSIGSVLDEADREVSNLTDRAFRSLCISEDTSFHDSDLALSPEITSQVSGTFHQETVSHANRKSGIWSQLPSQGTEHSGWAATFQQQPKYVQGEEKYPKNSPLPTPVQRRLEVPISGLRSSSKPISKVSSLIRSFDRTEAQPCDSRPPPSKPPALKNTPKFAHPPESGVNFCFDSAFLTVRRVPAGVSSTHQSSHQPCRAPGEPEPPTNPEIACHSSDSLLRAPDRVAGSCEPRFPSPSLKPPKAETGRGKEWISRGTFLHSENSAFESWDAHQPKLRERKDITETTPESKAPKHYEDMPLLKEPYPAESKLSPCQGRANCAQEENRSPSGIQSTSGAWGARDSGSQVFPVEGNASQIDPQVKRNQAPWRKPKTGKGGTDGPHDASEDKKQPNRKGLPLYSKLNPQGQLPENGVLDLPEESSDHYSSPFNISKLLTPIISTKHVLETSDTQPVETSPSPPGQLNGYQEKESSEAQSRDSYKSKAPSLLFNLKDVRKRVKSTYSPLPLLKGFDEKTRGKLDGKQEPLSNGVTLPNGLEENPPTAELVKETLDDAPSVLHSSTQKDPAMDSRESFADSHPTFSSPSASSKTHFSINGEAAERNSHEKEEANGESEQGLSEGGWHPDSRENLPRKHLSLKLCNRDSETGQATEKMKPRQLEKRLSRSISQETEPEREMGFQNLPVSQKFSPGPLSPEEEDVFYSDSQSDFTPCVQTKAKFSTSSSDQSFASFEDQQKMWFTEGPREDGKSHVSLGDNQKDEKETEVEKEEPQQCALHNGVEEHRQKETQRKAQGVLGGRPRKASAEEVSVRGSWTGADKDTALSHAKDPTPLPASTNKHRLFPIKDNTLRATPVIKPIILPLLRTVSSEDSLSGGHKENELPRQPWGEDAGGLGASESQEMRNTPLSNSTPSTEQKCVVYEGVEEDPVHTAAQDETSQQTRKGSFSFLPLVEEGGKTKPPPDTADERLAHEKSRSADSGKLEAPQHIPTIALHSDDLEDSPPSLPQHTCWEEQGFKSHFLSAPRAGPSGRRPVPSEAATSPNPSSLGGSSTCSPAASSIWEDASQAAGEHWQRQEPPGPGPWASPGPSGPTGLTRREDMTRGLTWEAEGSDPHLERLADFRTLSPRGIFLTGAAEKPEPSSLLEKAAGKPPAVPPKTEKALRRAKKLASKRRKSDQMSEKHTEAWEGKSFTEDAQGTEQRPVSPGKGPRPRFPEVRSLPPPTHRHSVSCGWEPAGRRPWGSQSLIPLPPYPATQKVLQDPQSGQYFVFDMPLQVKIKTFYDPETGKYVKVSVPSSEEDPSEPPLQDALTAPYLLYPGFQPVPVTSLMPLRCSSQLAAPTFLRQGSSHRPQSSQGARLQPPPERLGESAQHVSSAQRPRGPPLSPEEEGAEAPSLSIISTDDLEDFATEGVS
What is the function of this protein?
Plays an important role in cardiomyocyte hypertrophy via activation of the calcineurin/NFAT signaling pathway.
What are the official names of this protein?
Cardiac-enriched FHL2-interacting protein.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line.
Protein: RS19_BRABE
Sequence: MPGGVTVKDVNQQEFVKAFAAFLKKSGKLKLPEWVDLVKTAPHKELAPYDPDWFYLRAASTARHLYMRGGVGVGAMCKIYGGRKRRGTKPAKFRVCSRGVSRTVLQSLEGIKMVEKDAAGGRRLTSQGQRDLDRIAGQVATAMRKAQ
What are the official names of this protein?
40S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
Protein: MPIP_SCHPO
Sequence: MDSPLSSLSFTNTLSGKRNVLRPAARELKLMSDRNANQELDFFFPKSKHIASTLVDPFGKTCSTASPASSLAADMSMNMHIDESPALPTPRRTLFRSLSCTVETPLANKTIVSPLPESPSNDALTESYFFRQPASKYSITQDSPRVSSTIAYSFKPKASIALNTTKSEATRSSLSSSSFDSYLRPNVSRSRSSGNAPPFLRSRSSSSYSINKKKGTSGGQATRHLTYALSRTCSQSSNTTSLLESCLTDDTDDFELMSDHEDTFTMGKVADLPESSVELVEDAASIQRPNSDFGACNDNSLDDLFQASPIKPIDMLPKINKDIAFPSLKVRSPSPMAFAMQEDAEYDEQDTPVLRRTQSMFLNSTRLGLFKSQDLVCVTPKQSTKESERFISSHVEDLSLPCFAVKEDSLKRITQETLLGLLDGKFKDIFDKCIIIDCRFEYEYLGGHISTAVNLNTKQAIVDAFLSKPLTHRVALVFHCEHSAHRAPHLALHFRNTDRRMNSHRYPFLYYPEVYILHGGYKSFYENHKNRCDPINYVPMNDASHVMTCTKAMNNFKRNATFMRTKSYTFGQSVLASPDVNDSPTAMHSLSTLRRF
What is the function of this protein?
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic and meiotic progression (PubMed:3955656, Ref. 3, PubMed:7498766).  Directly dephosphorylates cdc2 and stimulates its kinase activity (By similarity).  Required for the G2/M transition of the cell cycle (PubMed:15629716).  Required for induction of meiosis II (Ref. 3, PubMed:7498766).
What are the official names of this protein?
M-phase inducer phosphatase, Mitosis initiation protein, P80.
What is the protein family that this protein belongs to?
Belongs to the MPI phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Accumulates in the nucleus in cycling cells; nuclear localization is the highest in G2.
Protein: REPA_CSMV
Sequence: MSSLPVSESEGEGSGTSVQVPSRGGQVTPGEKAFSLRTKHVFLTYPRCPISPEEAGQKIADRLKNKKCNYIYISREFHADGEPHLHAFVQLEANFRTTSPKYFDLDEFHPNIQAARQPASTLKYCMKHPESSWEFGKFLKPKVNRSPTQSASRDKTMKQIMANATSRDEYLSMVRKSFPFEWAVRLQQFQYSANALFPDPPQTYSAPYASRDMSDHPVIGEWLQQELYTVSPQALSLHAGISEEQARIDLQWMSDLTRSGALESGDEACTSVGQQELERLLGPEVLELITTGSTQ
What is the function of this protein?
Implicated in enhancement of V-sense gene expression.  Acts a an inhibitor of C-sense gene transcription (By similarity).
What are the official names of this protein?
Replication-associated protein A, RepA.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: EHD1_BOVIN
Sequence: MFSWVSKDARRKKEPELFQTVSEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPNLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPAQVVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKIWKLADVDRDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
What is the function of this protein?
ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis.  Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes.  Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth.  Plays a role in myoblast fusion.  Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing.  Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis.  Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29.  Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension.  Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis.
What are the official names of this protein?
EH domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. EHD subfamily.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Note=Preferentially associates with tubular recycling endosomes (By similarity). Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes (By similarity). Localizes to the ciliary pocket from where the cilium protrudes (By similarity). Colocalizes with BACE1 in tubulovesicular cytoplasmic membranes. Colocalizes with BACE1 and APP amyloid beta proteins in hippocampal mossy fiber terminals (By similarity).
Protein: DCTA_BURVG
Sequence: MKKKPFYKVLYVQVIFAIIVGVILGHFYPALATDMKPLGDGFIKLIKMVIGPIIFCTVVTGIAGMEDMKKVGRVGGKALLYFEIVSTFALLLGLAATHLLRPGVGFNIDPATLDGKAVASYAAKAHGQSTVDFLMHIIPNTMVDAFAQGEILQILLIALLFGSVLAHLGERGKVVTDFIDGLTRVLFGIVHIVTKLAPIGAFGAMAFTIGKYGVGSLVPLLKLIGTFYLTSIVFVLVVLGTIARFTGFSIVRFVSYIKEELLIVLGTSSSEAALPQLMEKLEKAGCSRSVVGLVVPTGYSFNLDGTNIYMTMAVLFIAQATNIELTWMQQLTLLAVAMLTSKGASGVTGAGFITLAATLAVVPTIPLSGMVLILGIDRFMSECRALTNIVGNGVATVVVSAWEKELDRNKLRDALKGNRDVTPTETAGV
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VEL1_YEAS7
Sequence: MSFLSIFTFFSVLISVARAVRFDLTNVTCKGLHGPHCGTYVMEVVGQNGTFLGQSTFVGADVLTESAGDAWARYLGQETRFLPKLTTIASNETKNFSPLIFTTNINTCNPQSIGDAMVPFANTVTGEIEYNSWADTADNASFITGLANQLFNSTDYGVQVASCYPNFASVILSTPTVNIFGKDDTLPDYCTAIQLKAVCPPEAGFD
What are the official names of this protein?
Protein VEL1, Velum formation protein 1.
What is the protein family that this protein belongs to?
Belongs to the VEL1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Intracellular soluble fraction.
Protein: TSAT_COMTE
Sequence: MNFRRRLCTAALIAALPLASQAQNNTLLLNSVLAPQNPMTKMIVKPWAEKIAQVTEGRVKVDVAPSSLAAPQQQLASVNKGVFDIAYQFHGLLTDQVKLNQIAQLPFVNTTARGSSVALWRTYQKHFAKANELGEVQVLALFVQPPGVMFGMKGPIDGMDKLKGRKVYALPGVPSAMMESAGAAVVAAPGARSYEIVSGKTVDAFVGYPTSDAEGLKTLSYATDVTDIPGNLTAVSWVLFMNKKRWAALSEKDRKAIESISGEAFAQGMKQYDDLETKVRSEAAAKGIKFHMANDAFVKELQTLATPITQAWLKDASSRGVNGQEALDFYRAQAAANR
What is the function of this protein?
Involved in the uptake of p-toluenesulphonate (TSA).  Forms a large, general diffusion pore with a preference for anions.
What are the official names of this protein?
Outer membrane transporter protein TsaT.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: TFP11_DROME
Sequence: MSDNDYERFEITDYDLDNEFNINRPRGRQSRHQQIYGIWADDSEEESGGEGGTKRRGRAARKPKDYTMPVNFVAGGIQQAGKKKKKALQADDEKGSQKEGAEADQGEESDDSAASGRPAFGQNDPGSSNSSSEEERPTLSRKQPSTTFQHRSHIASERNVGAWEQHTRGIGAKLLLQMGYEPGKGLGKDLQGISHPVQAHVRKGRGAIGAYGPETAASIGGKTNKSIKVDEDVREAKEFKDQLNKWRKGSAGGAEPMERQGKRYYYKSVEEVIAKGHTSGHLLSEKLSKKLGNVRVIDMTGPEKRVLSGYHALGQAKITPEETLYDTEATEKGSAPACVFAMPELTHNLQLLVSQCEQQIIAIDNQERECSSQQAALESEHRKLEEIVQLERNHIRTLEESLERVERLIDNPDLSLPQAERLFRELLVDYAAEFHEFGLADLAAGVIAPLLKRELVQWQPLENPTEPLPLIKKWRGMLQQGDAAEQQPRNVFDPYSSLIWAGVMPSFRSSAAAWQPKEHPPMASLLDAWAPLLPSWVLDSVLEQLVLPRLVAGVQEWDPLTDTVPIDSWVLPWHAILGSKLEEAVYPQIRSKLGIALRAWSPHDRSARAMLTPWQKAFPEEEMQEFLQRYIVPKLQATLGELIINPMHQDLELWQQVWEWHELIDPMYMAQLLDRHFFPRWMQVLVVWLNQSPDYAEISRWYTGWKSMLSEPLLREPSVKEHLRRALEIMHRASDTLLQPTVTPTPPPPVPPAPVIMMDLIHPPAQLEFKELVSQQCADLGIIFAPLPGRREMGKQIYRVGKLFCYIDRHVCMVSDGSFSNWKPVSLNHLLERSQTGIL
What is the function of this protein?
May be involved in pre-mRNA splicing.
What are the official names of this protein?
Septin-interacting protein 1, Septin and tuftelin-interacting protein 1, STIP-1.
What is the protein family that this protein belongs to?
Belongs to the TFP11/STIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MACB_HAEDU
Sequence: MKQPLIELKNIERYHTNGDTLTTVLKSINLKIYSGEMVAIVGASGSGKSTLMNIIGALDVPNSGEYFIYGRNIADLSGDELAELRCRHFGFVFQRYHLLSHLTAVKNVEVPAIYAMADKILRNQRANALLCQLGLEKQLENKPAQLSGGQQQRVSIARALMNGGDIILADEPTGALDSQSSQDVLKILKDLNRKGHTVILITHDLAIAEHADRVICIQDGKIVSDTANALESMIKPQNKRTFIDDAVIEVCQQHNTEKLNRPNEKNNIDNDNKENNNGYNRNDNSFLNNPKKKLNSSILRSFNSYAESFFMAFNMMMAHKIRTFLTMLGIIIGIIAVVFVIALGEGTKKKVLDEFSSLGNNTIDIFPGKWGDESDNVHTLNMEDLELLYQQPYVQRATPVLLHIAKARYLNKTMRSLINGVSHDFFMLKNYQLVTGRLFDQNDLTLSQPVGVIDKKSAKLLFDMDDPINKIIFIDDIPLSIIGVVESSSLQQNSGKEILIWIPHSTMATRILNQSYIQQISVQLQPNVSPLKSDKAIIDLLTIKHGQKDFYTFSSSRFLQSLNKTTQALTLMISSIAFISLIVGGIGIMNIMLVSVIERTKEIGIRIAVGAKERDIRFQFLIESTMVSLIGGCIGVGCALLFGGLFSLAETSIKIQFTLSSFLIAFLCSSMIGIVFGYFPARNAAKLRPVDALSRE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DRM1A_ORYSJ
Sequence: MRIASSSGILMDANGKANGSAPSALVAYFLGMGFSREMVFRAIKEIGDTDSEQILELLLTYQAIGSDPSVGNSSHSACDPQILEEEDEEEDVNWDEDDTVDNFDRATYSDGSGDEDFLQEMSEKDEKIKSLVSMGFPEDEDTEFSSFGGRKKTKLIDGSKKKRERYRSRPQWNQVPFDGSHEEPMPLPNSMVGFSLPNDGLRSVHRNLPDQALGPPFFYYENVALAPKGVWTTISRFLYDIYPEFVYSKYFCAAARKRGYIHNLPIKNRNYTRGVSRTARYRALGNSFQVDTVAYHLSVLRDIFPNGMNVLSLFSGIGGAEVALHRLGICMKTVVLVEISEVNMTLLRSWWDQTQTGTLIEIADVQNLTAERIELFIRRFGGFDLVIGGSPCNNLAGSNRYHRDGLEGKHSALFYHYYRILDSVKTIMASIFGAKGKLFRHVRKALLLKQSSSLTLKTEQDPSNNSDKDSMDK
What is the function of this protein?
Involved in de novo DNA methylation.  Involved in RNA-directed DNA methylation (RdDM).
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase DRM1A, Protein DOMAINS REARRANGED METHYLASE 1A, OsDRM1A.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. DRM-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMG_ALTMD
Sequence: MFYTEAFDVIVVGGGHAGTEAALAAARMGANTLLLTHNIETIGQMSCNPAIGGIGKGHLVKEIDALGGAMALAIDKGGIQFRTLNSSKGPAVRATRAQADRTLYKNAIRDIVENQENLTLFQQSVDDLIVENDRVCGVVTQMGLKFKAKSVVLTVGTFLGGTIHIGLENYRGGRAGDPPSIALADRLRALPFRVDRLKTGTPARLDARSLDFSVMQPQPGDSPTPVFSFMGDRAMHPTQIPCYITHTNEKTHDIIRGGLDRSPMFTGVIEGIGPRYCPSIEDKITRFADKTSHQIFVEPEGLNSIEVYPNGISTSLPFDVQMNLVRSIKGFENAHIVRPGYAIEYDFFDPRDLKQTLETKFIQGLFFAGQINGTTGYEEAGAQGLVAGANAALQVQQKDPFILRRDQAYMGVLIDDLATMGTKEPYRMFTSRAEYRLLLREDNADSRLTAMGREIGLVDDARWAKYNDKMEAVETELQRLRGQWIHPDHAATPQLNTMLKNPVSREHSLEELIRRPEMTYSQLMKIESVGPGIDDPIAAEQVEIQIKYAGYIARQMDEIAKTQRHENTLLPIDMDFSKISGLSNEVVAKLTEARPETIGKASRISGITPAAISLLLVYLKKHGMLRKQDKISA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIPF6_DANRE
Sequence: MVVSHLNRTVTSLNELFEHHAHFAGLSDISISEDIPVEGDISVPVGSQNADNDFSTLDEPVKDTILRDLRAVGQKFVHVMYPKKSSALLRDWDLWGPLLLCVTLALMLQGGSADSEEDGRPQFAEVFVIIWFGSVIITLNSKLLGGTISFFQSLCVLGYCILPLTVAMIVCRIVLLGGSGVVSFAVRLIVVTASFSWSTFASTAFLADSQPTNRKALVVYPVFLFYFVIGWMILTFSPSH
What are the official names of this protein?
Protein YIPF6, YIP1 family member 6.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Note=Evenly distributed between cis- and trans-Golgi apparatus. Mainly localizes within medial-/trans- Golgi and trans-Golgi network (TGN), while less so within cis-Golgi.
Protein: RBG10_HUMAN
Sequence: MIENSSWSMTFEERENRRLQEASMRLEQENDDLAHELVTSKIALRNDLDQAEDKADVLNKELLLTKQRLVETEEEKRKQEEETAQLKEVFRKQLEKAEYEIKKTTAIIAEYKQICSQLSTRLEKQQAASKEELEVVKGKMMACKHCSDIFSKEGALKLAATGREDQGIETDDEKDSLKKQLREMELELAQTKLQLVEAKCKIQELEHQRGALMNEIQAAKNSWFSKTLNSIKTATGTQPLQPAPVTQPPKEST
What are the official names of this protein?
Rab GTPase-activating protein 1-like, isoform 10.
Protein: NEF_SIVCZ
Sequence: MGTKWSKSSLVGWPEVRRRIREAPTAAEGVGEVSKDLERHGAITSRNTPETNQTLAWLEEMDNEEVGFPVRPQVPTRPMTYKAAFDLSHFLKEKGGLEGLVYSRRRQEILDLWVYHTQGFFPDWQNYTTGPGTRFPLCFGWCFKLVPLTEEQVEQANEGDNNCLLHPICQHGMEDEDKEVLVWRFDSRLALRHIAREQHPEYYKD
What is the function of this protein?
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Virion. Secreted. Host Golgi apparatus membrane. Note=TGN localization requires PACS1. Associates with the inner plasma membrane through its N-terminal domain. Nef stimulates its own export via the release of exosomes. Incorporated in virions at a rate of about 10 molecules per virion, where it is cleaved.
Protein: RL20_PSEP1
Sequence: MARVKRGVIARKRHKKILKLAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQKKRQFRALWIARINAGARTNGLSYSRLIAGLKKASIEIDRKVLADLAVNEKAAFAAIVEKAKAVLA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: GSIA_ECOL6
Sequence: MPHSDELDAGDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLQRRSREVIELSEQSAAQMRHVRGADMAMIFQEPMTSLNPVFAVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQTILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQEPPIEQKTVVDGEPVLRVRNLVTRFPLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPCKLQALRRDIQFIFQDPYASLDPRQTIGDSIIEPLRVHGLLPGKEAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAAVPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Glutathione import ATP-binding protein GsiA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Glutathione importer (TC 3.A.1.5.11) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DAPA_CORJK
Sequence: MSTGNAATRGSAHFGTISLAMVTPFKKDGSIDLDAGVALAGHFVDEGCDSLVLAGTTGESPTTGATEKLDLLRAVRSELGDSVKLIAGSGSYDTAVTVEMSRASQEAGADSLLVVTPYYSRPSQEGIYQHFTTVADAVDIPVCVYDIPSRSVVPVEPETLHRLADHPQIAAVKDAKGDLAAGMELIENTDLAWYSGDDPLNLPWLAAGATGFISVIGHVATRQLKQLRDAFDAGDIATARSIAVQLQPLQKAQARLGGVTFAKAALKLKGKDVGAPRLPIIEPTAAEMDQLAQDLQAAGV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYX_BRUA1
Sequence: MSAEERLIELEIRVAEQEKTIDELSSVLTEQWKTVDQLSKKLNALTNRFLELEEQAAPDVPVTKPPHW
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: PANB_ALTMD
Sequence: MKKVTVSGLLKKKQAGEKITSLTAYDASFAKMFDEQGVDALLIGDSLGMVLQGEDDTLPVTIDDIAYHTKSVRRGTERAFVLADMPFMSYATPEQTYANAAKLMAAGASMVKMEGGSWLCDTIKGLNLRGVPVCGHLGLTPQSVHVFGGFKVQGREASQAEKLLSEAKALEEAGIQLLVLECVPSSLGKAVSEALTIPVIGIGAGKDTDGQILVMHDMFGISANYMPKFSKNYLVETGDMRKAVSKYIEDVQSGAFPSPEHSFQ
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.