PharMolix/UniProtQA huggingface dataset:
Protein: SRP14_PONAB
Sequence: MVLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIPKKGTVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKTKKTKAAAAAAAAAPAAAATAATTAATTAATAAQ
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (By similarity).  The complex of SRP9 and SRP14 is required for SRP RNA binding (By similarity).
What are the official names of this protein?
Signal recognition particle 14 kDa protein, SRP14.
What is the protein family that this protein belongs to?
Belongs to the SRP14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_LEPIN
Sequence: MNHFISGIPIHYYLILAMIIFTIGVAGVMVRRSAVLIFMSVELILNSVNLVFVTFSKALHQIDGEVVVFFVMAIAAAEAAIGLAIVIAIHRIKKTSYVDEMNLMKW
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXC_LAWIP
Sequence: MQQTTIQRSITFSGIGVHSGQCLNVTLHPASENTGIVFEVITGDTRHTLIPSPSAVIATKLATTIGNKNITISTVEHLLASIRGLEIDNIRICVEGAEIPIMDGSAKIFTNELLQAGIKYLPATKKILQVIKPVEFIKGEKRIRALPYNGFKLDYTINYIHPIIGHQRLVLDVTPTTFLSIANARTYGFLKDVEQMLKNGLAQGGSLENAIVLDSTKVINPEGLRYPDEFVRHKALDFIGDMAMMHLPLQGYFEIYCSGHQHNNQFLHKLQDENALALVTLEGEKTQNLYQNITPLYNDVLALL
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: SYH_BIFA0
Sequence: MAKGASISGFPEWLPAERVVEQRVIDTLREVFELNGFIGIETRAVEQGSSLLKKGETSKEIYLLSRLQEVGHESDIPVEQRLGLHFDLTVPLSRYVVEHSGALPFPFKRWQIQKVWRGERPQEGRFREFVQADIDVVGDGTLPSHYEVELPLVMVNALERLREFGLPKATVHANNRKLSEGFYRGLGLTDIEGVLREIDKLDKIGPQAVTDLLVETCGATEAQANACLELAQVTAEDGQELIEKFNGLCEIHHIPFDGDEYAMAKEGLDTLSMIIDEARRIRPGSVMADLKIARGLDYYTGSVYETFLEGASDLGSICSGGRYDNLATQGNRKYPGVGLSIGLSRLVSYMLHRAGATASRMSPACVLVAVWDEENRGDSNAIANTLRSRGIAADVAPTAAKLGKQIKYADKLGIPYVWFPNENPENDGSDEVKNIITGDQRPADAQSWQPDTVYAQQTVSINADNR
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCEMO_STRA7
Sequence: MARRSRYISLAAVMATLLSALGVTFLLGQGRAEAHGVAMMPGSRTYLCQLDAKTGTGALDPTNPACRSALDTSGATALYNWFAVLDSNAGGRGAGYVPDGTLCSAGNRSPYDFRGYNAARSDWPRTHLTSGSTIQVNYSNWAAHPGDFRVYLTKPGWSPTSELGWDDLELIETVTDPPQRGSAGADGGHYYWDLALPSGRSGDALIFMQWVRSDSQENFFSCSDVVFDGGNGEVTGIRGSGGTPTPTPTPTTPPTTPPPTHSGSCMAVYNVENSWSGGFQGSVEVMNHGTEPLNGWAVQWKPGNGTTLGGVWNGSPTRGTDGTVKVRNVDHNRVVPPDGSVTFGFTATSTGNDFPVGTIGCVAP
What is the function of this protein?
Involved in the degradation of lignocellulosic biomass.  Catalyzes the oxidative cleavage of glycosidic bonds in cellulosic substrates via a copper-dependent mechanism.  Degrades phosphoric acid swollen cellulose (PASC) to oxidized cellooligosaccharides with degrees of polymerization of 4-8.  Also shows activity on agricultural fiber paper pulps such as flax pulp.  Is not active on chitin.
What are the official names of this protein?
Lytic cellulose monooxygenase, Lytic polysaccharide monooxygenase, LPMO, SamLPMO10C.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXK_BARQU
Sequence: MLISTPHFWWKDKSFLRFLLTPVSWGYGYFSHRCMVRELPVIDLPVLCIGNFTCGGAGKTPVVIAFAKVAKELGFLPGVVSRGYGGAVKGVHLINEQFDNARDVGDEALLLARHAFVAISSNRYVAAQRLKEEGCNLILMDDGFQSRRLYMDYALLVVDAMRGFGNGAVFPAGPLRAPLKTQFSLMDSVLLIGHSDACENVVFLVTRTGKALHHAHLKSLASDEVMGKSFLAFAGIGNPNKFFKSIKELSGRVVQTYSYPDHYFFTDTDLKNLIQQAKMNNLWLATTAKDYTRIQTSHVQKDLKNLIVFDVEVDFVQEDFCRMILEEVMSRFRERKTLFNLHF
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: ATPE_NEOYE
Sequence: MTLNIRIIAPDRTVWDAEAQEIILPSSTGQLGILTGHAPLLTALDIGVMRVRVDKEWMPIVLLGGFAEIENNQLTILVNGAEEASQIDLSEAEKNLDTATQLLSDASSNKEKIEATQKIRKARARVQAATAATS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PFKA_PASMU
Sequence: MIKKIAVLTSGGDAPGMNAAIRGVVRSALAAGLEVYGIYEGYYGLYHNKVKQMTRYSVSDIINRGGTFLGSARFPEFKDPAVRAKCAEILRSHGIDALVVIGGDGSYMGAKLLTEEHGFPCVGIPGTIDNDVAGTDYTIGYQTALQTAVEAIDRLRDTSSSHQRISIVEIMGRHCSDLAISAGIAGGCEYIVASEVEFNREELIQQIERSIIKGKRHAIIAITELICDVNELAREIESRVKHETRATILGHIQRGGTPCAFDRILGSRMGVYAVDLLMQGKGGYCVGIQNEQLVHHDIIDAINNMRREFKADWLALSKRLD
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_CLOB1
Sequence: MEKIKVALVSLGCDKNRIDSELMLYKLNEEAELVKDPKEAQVIIVNTCGFIETAKEESINTILQMASYKKTHNCKVLVVTGCLTQRYKGELKELIPEMDIMLGVNDYDKLLESIKVFLKSGEKSFYHKYSDTKINEGNRILTTPTYTAYVRIAEGCNNFCTYCAIPRIRGKYRSRKKENILKEVENLAKQGVKEIILIAQDTTMYGIDIYGKKVLHELLRDISKVEGVKWIRLLYCYPEEITKELIEEIKNNDKVCKYLDLPIQQISNSVLKRMGRKTTKETIINIIKKLRKEIEGITLRTSLIVGFPGETEGEFSELKEFVSDVKLDKLGVFKYSKEEGTSAALMEEQIDEEIKEKREEEIMILQQSISKDINKEKIGKTYEVIVEGTKEDMYYGRNYEMSPEIDGEIYFEKDENVKIGDIIKVKVTHSLEYDLIGVVYNELSK
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNB_CANDC
Sequence: MSAPCHCQHADDDYSSIKKLSVLSPELQQEFKDPNHPANLICELCRLFYDNNWVTGTGGGISIRDVDGPNPNLVYIAPSGVQKERIQPWEMFLVELPQEKILRTPNDIPKELTKSYKYKPSACTPLFISCYTLRNAGACIHTHSQHAVMVTLFFENEKEFVISHIEQIKALPKLKYNQETGKIEKIGSMEYYDKLVIPIIENTPHEEDLTDSLQEAIKNYPGASAVLVRRHGIYVWGETVWKAKVYNEAIDYLLELAVKMKLAGIPLVKEE
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H3_CANGA
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RPOA_DESVV
Sequence: MLIKQGDRLINTRNWSELVKPEQISRDGEVSDTMYGKFVCEPLERGYATTIGNAMRRVLLSSLQGAAFVAVKISGVQHEFTTIPGVLEDVTDVVLNLKQVRLAMDTEEPQYLELKVDKRGAITAGDVRTNQHVMVLNPDQHIATLTEDIELTFELEVRMGKGYVPADMHEGLSEEIGLIKLDASFSPVRKVAYTVEQARVGQMTNYDKLILEVWTDGSVSPEDAIAYSAKIIKDQISVFINFDERISGENSNGSADSGEFNEHLFKSIDELELSVRATNCLKSANIALVGELVQKSENEMLKTKNFGRKSLDEIRRVLGDMGLDFGTKVDGFEKKYQEWKRKQQHEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RBFA_PSYIN
Sequence: MAKEYSRTSRVSQQVQKELARILQQEVKDPRIGMVTISGVDVTRDLAYAKVFVTFLTVGDQTNDESLEGLNAAAGYIRRLLGKAMRLRIVPEVRFCFDSTLTEGLRISELVSGAVKADKTKLAASGRTEEDED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SA1_NAJOX
Sequence: LKCNKLVPIAYKTCPEGKNLCYKMFMMSDLTIPVKRGCIDVCPKNSLLVKYVCCNTDRCN
What is the function of this protein?
This three-finger cytotoxin is a basic protein that interacts and penetrates into the cell membrane, with the tips of all the three loops.  Cytotoxins which have a 'Pro-30' (P-type) interacts with membrane stronger that those which have a Ser-28 (S-type).  CTI interacts with membrane weaker than CTII.
What are the official names of this protein?
Cytotoxin 1, Cytotoxin I, CTI.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: TRUA_THESM
Sequence: MRIALKIAYDGTKFYGFQRQPDLRTVEGELIKVLKKLGIIEDVKEANFKGASRTDRGVSALGNVIAFNTAKPELAEARILNHHLRDIWILGKAEVPEDFHPRFWAKNKIYRYYLFDEGIDVIKLKACAEAFLGRHDFSNFARLEEFRKPVREINRIDVFSRGRIIVVEIEGKSFLWEMTRRIITALKLCGLGVLSIGDVELMLKEKVDKKLPPAPPENLVLWEVGYEGIKFEVDAYAIEKVKREFLERFRKYLTKSAILEDWLISL
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CXP2_PARCG
Sequence: GWPAYPGSNGIRSSVCQKKLGCGSKNLASLGVCKAFCLGRKRFWQKCGKNGSSGKGSRISNPVLAHAVEKASKGLIKVTDMAVAAIVKYAGKK
What is the function of this protein?
Cytolysin that shows hemolytic activity (on bovine erythrocytes, HC(50)=5. 75 mg/ml).  This hemolytic activity is completely inhibited by small unilamelar vesicles composed of PC/PG, PC/PI and PC/PS in 1:1 molar ratios (with at least 100 mg/ml concentration).
What are the official names of this protein?
Parbolysin P2, Parbolysin 2.
What is the protein family that this protein belongs to?
Belongs to the worm cytolysin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS6_STRCO
Sequence: MRHYEVMVILDPDLEERSVSPLIENFLSVVRDGGGKVEKVDTWGRRRLSYEIKKKPEGIYSVIDLQAEPAVVKELDRQMNLNESVLRTKVLRPEMH
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y2081_MYCTO
Sequence: MFANAGLSPFVAIWTARAASLYTSHNFWCAAAVSAAVYVGSAVVPAAVAGPLFVGRVSATIKAAAPSTTAAIATLATAANGQLRERGGAGGWVGVHCPVVGGGGVGHPRKAIAAAVSVHSTCMPAAFGGHLGLGDRSRSVSLSGTP
What are the official names of this protein?
Uncharacterized protein MT2143.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EAF1_ASHGO
Sequence: MSVLKKDSTSEKRTQLESILEERNNKLTQLFWLSRLNELKSGGDLQSVRQELAEFLVQNDLTKNLTFDISSLRTYRPQEPPMDRRPLRSKSSTPLENGTINRKREDAEPHMEETRKRLREHIIPEEDDDREHEQRPVKLQKVGLSHDEELPKRLEPPTIPIRKISSAGDNQETGSVIGEKKSEQPVSTSRNRPIHTQLSTNPFYQHMDISTLRAEPTPVEVKRKRNYIIDEIIKTQSKSTDTSDSHSTAGGRDSVYLVMKETVPSKLARAIPLSELKYVSQTLPLIRLIPPTHKALTTDLYNTALNEGRITVVSSRIEELRRLNLWSLRQPKKFLDPWRQKQPSTHRGYMLEEARWMREDFHEFKKFKVSVCAVNSKAIMDYWKYGKACCIKRRSISHLQKSVNEVQEADTLGNIDDLLNKISDKKLAGMIEEQKKVIAVDAKLSSSKIAPSEEIHAPHIWEDPLDELDEQGCKPIFKTYMSYNGVSPLEKTILEDLPIYKGILDEQAAEDNSVPFVPISKSTVLLDDDYFMKLIEKDIVDDEPSFVALSKRRGMFYGNRRSHYLKPPSAPALRYLKFRTPTIWSPEDDQELVKNINQYAYNWDLIGALVSSSNGRSYISNIERRTPWQCFERFVQLNEKFSVHDMKGPRANAAQMWLYEAHKLQQQQKRRISPLGVGSESIQRGHRRLRWATMFEAMRKTIKKRENAPRPNPSQPRKPLDVKSAAVPTPAEMSELKAQRDETLRREGQMRRAAKQRIHLAQLQQQQQRVQQDVVQQRPQSRSQPDPPLSQQIPRVQSPRPQQPLAQQLIEDKGKLLPGVSVSAPTSKEASNNGKNLMALRQVQSSPVNGDLQKATAQVPPRGPNKPLTEKEIIESYARKIIAQKPDFTPELALKAAESYYQNVTLKQNTIGKQIVSQPLSAATVSTPPSNGRAVHKIRSPTPQEILQRIQQKKNDS
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF1, ESA1-associated factor 1, Vacuolar import and degradation protein 21.
What is the protein family that this protein belongs to?
Belongs to the EAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL17_BRADU
Sequence: MRHGKVHRKLNRTAEHRRAMFANMAAALIKHEQIVTTLPKAKELRPIVEKLVTLGKKGGLAMRRQAISEMRDKDQVKKLFDVLATRYKDRQGGYTRIIKAGFRYGDNAAMAVIEFVDRDVDAKGQDSGPVQEKEAEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HIS8_ECOBW
Sequence: MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVEFQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLDNWQLDLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAEREYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALRAEQV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: FOLD_COXBR
Sequence: MIARILDGRTCAEKVKARVKENIRLLQEKGLPSPGLAVILVGNDPASATYVAHKERACQAVGIRSTVYRMPNTITESELASKIDECNRDSNTHGILLQLPLPAHIDPANLLERIRPDKDVDGFHPYNLGRLVQRRPALRPCTPYGVMTLLTETHENLEGKHAVIVGASNIVGRPMALELLLAKCTVTVCHRFTRDLAEHVKSAELLIVAIGKPGIIQSEWIKPGAIVIDVGFSRLSPNKIAGDIDFETAKERASWITPVPGGVGPMTVATLLENTLQAAQTFL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HSLU_HAHCH
Sequence: MSSMTPREIVQELDKHIIGQDSAKRAVAIALRNRWRRMQIDEGLREEVTPKNILMIGPTGVGKTEIARRLAKLADAPFIKVEATKFTEVGYVGRDVESIIRDLADMAIKLLREKEMTKVENRALDAAEERILDALLPPARSFNSDAPVEKESAARQVFRKKLREGTLDDKEIDIEIKATPVGVEIMAPPGMEEMTSQLQSMFSNMSGDRKRTKRMKVAEAMKKVKDEEAAKLVNEEEIKQRALRAVEENGIVFIDEIDKVAKRSETSSADVSREGVQRDLLPLIEGCTVSTKFGMLKTDHILFIASGAFHLAKPSDLIPELQGRLPIRVELDALSPSDFQRILTEPNASLTEQYVALMKTEGVDISFSEGAIQRIAEIAWKVNEKTENIGARRLHTVMEKLLEEVSFAAGDKIRDSFEVTAEYVDKCLGELSEDEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_MESHJ
Sequence: MKKIIIGNWKMNKTVSETRDFIQKFDIFYQENVGKIKEDLDFAIAPSFISLSLISKSLTKKLEIAAQNLSQFDSGAFTGEISGKMLQDLGTKYVIIGHSERREIFKEKDEELKNKILQAQKYDLIPVFCVGESLLEFEAGLTKKVIISQINAIKSVLNFQKAIIAYEPIWAIGTGKTATAAIAEKVCGLIKENFGKNTMVIYGGSVNSKNINELVSQKSIDGALVGGASLDPEEFGKILVNS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_THERP
Sequence: MVRVKRGVTKHRRHKKILELAKGYQLGRSKLYRHANEAVLKALRYQYRDRRARKRDFRRLWIIRINAAARQHGMPYRDFIHGLKQAGVEVDRKMLADLAVHDPSAFGQLVEVARRAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: BPT_NITMU
Sequence: MSKLNDLPASTLQFYTTASYPCSYLPEQLARSQVATPSHLIDTIVYGGLVQAGFRRSGAFTYRPFCDNCRACLPVRVVVDSLALRRSQRRSWNRHRHLVATQHDLYYHPDHYALYLRYQAQRHSGGGMDRDSREQYRHFLLPSNVDSKLVEFRENGVLRMVSIIDELPDGISSVYTFFDPDVPGASFGTYNILWQAHQCRELKLPYLYLGYWIKDSRKMAYKAAFRPLQALINGQWELLENLSDYPSCAFP
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_SALTY
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGNPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRLNARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RLME_METTH
Sequence: MGKRWQAERKRDHYYRSAKKENYRSRASYKLLQLNNKYKLIKKGDRVLDLGAAPGGWSQVALDKVGEEGLVVAVDLQRIKGFPAENFRAIRGDFTDPEVKDKIIRELGGRADVVISDAAPSLSGIRDIDHLRSVDLVENVLDIAYRVLDRKGNILIKAFQGPELDRVIKELRKDFWKLKTTKPASSRKASAEMYIVGRDFKGKEKWERIIH
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAR1A_MOUSE
Sequence: MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLQMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLMESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIKGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID
What is the function of this protein?
Involved in transport from the endoplasmic reticulum to the Golgi apparatus.  Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation.  SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).
What are the official names of this protein?
GTP-binding protein SAR1a.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus.
Protein: ORR23_ORYSJ
Sequence: MRAAEERKGVVPAARRRDQFPVGMRVLAVDDDPVCLKVLETLLLRCQYHVTTTNQAAIALKMLRENRDMFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSVNGETKTVLKGITHGACDYLLKPVRIEELRNIWQHVIRRKFSTRDRANLDFYEECNKPPNADSDHVHGHVTCGSPDQSGRPSKKRKEYCSEEEDEGEVNTQDIDDPSAPKKPRVVWSVELHRKFVAAVNQLGIDKAVPKRILELMNVEKLTRENVASHLQKYRLYLKRLSAVASQQVSIVAALGGRDPFLHMGGFEGLQGYQAFTSSAALSSFTPHGLLNSPRNNPAALGTQGVPASKSIQTMSGSHTLSHSINDANKYHLSLPGNQKGNLGQGLATSLGQTQMQQKWIHEETDDLSTILSGNGLSNGMSGTLQSVTSSPLLPQELAECTQAKIVSQPSIRTSSVSSEHIEGAVGVSSGLLESRVSQQSTIPLSGFSANGLLIHGSFNNTCANKLGGTSSSCAPARSSNDLMVARDTKGGASSFGGAMLLPPDTEQKYLNFGGGNGLKQKFDDRTADSLFDLKFVWSSVPSSQLASNIGAHHAMSQRWNNSSSNSSNIGARMIGQATSSGSTVIPQMKTDFLVSGDMAMPKNASDLSIPKLQSELSSSSCSFDGLLNSIVKVEKDDVTFSDDLGCGDFYSLGACI
What is the function of this protein?
Transcriptional activator that binds specific DNA sequence.  Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  May directly activate some type-A response regulators in response to cytokinins.
What are the official names of this protein?
Two-component response regulator ORR23, OsRRB5.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.