PharMolix/UniProtQA huggingface dataset:
Protein: CAPSD_HBVA9
Sequence: MDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTSAALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGNNLQDPASRDQVVNYVNTNMGLKIRQLLWFHISCLTFGRQTVLEYLVSFGVWIRTPPPYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: QTRT2_DROER
Sequence: MKFAIESISKNSGRLGQLRIKDGGPELKTPLLLQTTKGGSIPWLSADVFESHVSQKPQVLQFTLSTMDQMTEALTHWNSGGGNGLSGYVGLPGHLNILMVRDPCETTLSGGNDRDIMPLFTRRGKESLSSERYMEMVASFKPDIYQGLCDADTNLDSAKKRIQKSVDRTEKFMHYIYEHRCKVNSTLLAPIVGGYNTFARTQSIKHAREQPAGSYGGYIFEGFHTNGLTATTLDTSKLLPIVEHCVKQLEEDKPRILPGAYTPLTILELIRQGIDVFDSSYAYCASLNFKALTFSFVQDAVEHVPFLDITDEAIKEDFTPPLSECSCLTCQKHTRAYLHHLYKTNELLGPILLMVHNIHHYMAFFEEIRESVAKDALPQLTELVRNQNGKTQVDYSIAANNKVISKATMGKGFAAAAV
What is the function of this protein?
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_SHEHH
Sequence: MNFENLLIEVGTEELPPKSLRKLAESFLANFTEELTKAELSFDSAVWHASPRRLAICINQLALAQADKVVEKRGPAIAQAFDADGNPTKAAQGWARGNGISVEQAERLKTDKGEWLLHQARVVGVETKSLIADMAQRSLDKLPIPKPMRWGSNTTQFIRPVHTVTMLLGSEVVEGELLGIKSDRVIRGHRFMGESSFELDHADNYLVALKEKGKVLADYQARKAIIKTDAEAAAAKIGGVADLEDDLLEEVTSLVEWPVVLTASFEEKFLDVPAEALVYTMKGDQKYFPVFDNAGQLLPNFIFVTNIESKDPQQIISGNEKVVRPRLADAEFFFETDKKESLEARLASLETVVFQKQLGTIKQRVERISALAGYIATSINANSEEAARAGLLSKSDLMTNMVMEFTDLQGTMGMHYARLNGETEAVAVALAEQYKPKFSGDTVPTAPISICVALAEKLDTLVGIFGIGQAPKGAADPFALRRAAIGVLRICLENNLPLDLVDLIAKAQELHGENLTNENVAEQVLEFFMGRFRAWYQDQGVSVDVILAVLARRPTAPADFESRIKAVAHFRTLEQASALAAANKRVSNILAKVEGELPAAIDDKLLVEEAEKALAAKLAELQPQLAPLFAAANYQEALALLASLRESVDTFFEDVMVMADDEALKNNRLALLSSLREQFLHAADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_CHLPD
Sequence: MLQHTKSAELFEKAKQFIPGGVNSPVRAFKSVGGTPIYMAKGRGAYLTDVDGNSYLDYVGSWGPFILGSMHPRITAALEYTLKNIGTSFGTPIEMEIEIAELLCKIVPSLEMVRMVNSGTEATMSAVRLARGYTGRDKIIKFEGCYHGHGDSFLIKAGSGALTLGAPDSPGVTKGTALDTLNATYNDIESVKLLVEENKNNIAAIIIEPVAGNTGVIPAKPGFLADLRNLCDQNGIVLIFDEVMCGFRVALGGAQSLYGVTPDLTTMGKIIGGGLPVGAFGGKRKIMERVAPLGDVYQAGTLSGNPLALTAGLETLKILMDENPYPELERKAAILEAGFRDNMQKLGLNFVQNRVGSMACLFFTETPVESYASAITADIRKYGKYFHSMLEQGIYLAPSQFEAMFTSSMHTDEDLDKTIKANFNALQIACS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_STAAU
Sequence: MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFNEVKDDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SLD7_YEAST
Sequence: MSRKLCTLNFTLSGKQGSLVIRDIQLWSNRPTASKSTSELRGQFIQYVDLAKLPLWVRSTNMNTYRCYSTSATAQAYFKSKLRNANRGIVIELFDKVDQRSQEPAYLIIFRENTELNCFQVDLTMKHEFDGQVTKLKQDIGKTRASVSKEGSIDIIIQQSQQRKIGTKTEVYRNVHINDKRLQFNETLSKLILGGLRLRGISNSITDYQKLYKITFDAAEFTHRDELKRISMGSGEEVSFESLQETVETLLKLFTKS
What is the function of this protein?
Required for the proper function of SLD3 at the initiation of DNA replication.  Binds to SLD3 and reduces its affinity for CDC45, a component of the replication fork.  Required for mitochondrial morphology.
What are the official names of this protein?
Mitochondrial morphogenesis protein SLD7, Synthetic lethality with DPB11-24 mutation protein 7.
What is the protein family that this protein belongs to?
Belongs to the SLD7 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle pole.
Protein: LEC1_MYTGA
Sequence: MTFAKQSCFNSIILLSIATSYFKIGHKISELGNRIEKMTTFLIKHKASGKFLHPKGGSSNPANDTNLVLHSDIHERMYFQFDVVDERWGYIKHAASGKIVHPLGGKADPPNETKLVLHQDRHDRALFAMDFFNDNIIHKAGKYVHPKGGSTNPPNETLTVMHGDKHGAMEFIFVSPKNKDKRVLVYV
What is the function of this protein?
Alpha-D-galactose-binding lectin (PubMed:27187419, PubMed:23093409, PubMed:27321048).  Binds D-GalNAc, but not glucose or its derivatives (PubMed:27321048).  Has hemagglutinating activity towards rabbit erythrocytes (PubMed:23093409, PubMed:27321048).  Agglutinates bacteria.  Has bacteriostatic activity on both Gram-positive and Gram-negative bacteria including B. subtilis, S. aureus, E. coli and V. parahaemolyticus, respectively (PubMed:27187419).  Has a dose-dependent cytotoxic effect on the human globotriaosylceramide (Gb3)-expressing Epstein-Barr virus (EBV)-positive Burkitt's lymphoma (Raji) cell line (PubMed:23093409, PubMed:27321048).  Has dose-dependent cytotoxic effect on another Burkitt's lymphoma (Ramos) cell line, which does not possess the EBV genome, but also expresses Gb3.  Binds to Gb3 in these cells leading to phosphorylation of MEK1/2, ERK1/2, JNK and p38 kinase, activation of caspase-9/3 and to expression of p21 and tumor necrosis factor (TNF)-alpha (PubMed:26694420).  No cytotoxic effect on the human chronic myelogenous leukemia (K-562) cell line, which does not express Gb3 (PubMed:23093409, PubMed:26694420).  May be involved in innate immunity acting as an antibacterial or antifungal agent (PubMed:26694420, PubMed:27321048).  May be a pattern recognition receptor (PRR) involved in recognition of glycans found on parasitic or symbiotic microorganisms (PubMed:27187419).
What are the official names of this protein?
Alpha-D-galactose-binding lectin, Galactose-binding lectin, Lectin, MytiLec, MytiLec-1, R-type lectin.
Protein: 16D10_MELJA
Sequence: MFTNSIKNLIIYLMPLMVTLMLLSVSFVDAGKKPSGPNPGGNN
What is the function of this protein?
Plays a role in the differentiation or division of feeding cells (syncytia) induced in plant roots during infection.  Promotes host root growth.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 16D10.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host extracellular space. Note=Secreted into host root cells via the nematode stylet to transform the recipient cells into enlarged multinucleate feeding cells called giant-cells or syncytia.
Protein: NDHI_HORVU
Sequence: MFPMVTGFMSYGQQTIRATRYIGQSFITTLSHTNRLPITIHYPYEKSITPERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRFEKDIKRKQLLNYSIDFGVCIFCGNCVEYCPTSCLSMTEEYELSTYDRHELNYNQIALSRLPISIMGDYTIQTIRNSSESKINEEKSSNSRTITDY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HIS1_BIFAA
Sequence: MLRIAVPNKGMLSEPAWNMLAEAGYRLRSNPRQLVVEDPDNDVELFYLRPLDIAVYVGRGTIDVGITGHDLLVNSGTDAEEHMQLGFGASTFRFAAPNDSPITKLEDIEGKRVATTFDKLVHDYLVEHGINAETVHLDGAVESSVQLGVADLIADVVSTGTTLRNAGLRIFAEPLMHSEAVLIRSPRLEADDERLTILSRRLQGVLTAQRNVLMDYDIPVEKVSAAVDITPGFESPTISPLHDKQWAAVRVVVPKAKVNQLMDQLYEVGARGIIVTALQASRM
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_CARHZ
Sequence: MKSDIEIAQEAKLEPIVKIAEKLGLTEDDIELYGKYKAKIAAHVWDRIKDRPDGKLILVTAINPTPAGEGKTTTTVGLGDALSRLGKKTVIALREPSLGPSFGVKGGAAGGGYAQVVPMEDINLHFTGDLHAITTAHNLLAAMIDNHIHQGNELGIDPRRVVWRRVVDLNDRALRKVVIGLGGPAQGVPRETGFDITVASEIMAILCLASDLMDLKERFNRILIGYTYDQKPVYARDLKAAGAMTVLMKDAIKPNLVQTLEHTPAFVHGGPFANIAHGTNSILADKIALKLADYLVTEAGFGADLGAEKFFNVVCRFAGFKPSAVVIVATVRALKYNGGVPRAELNKENLEALEKGFANLEKHIENIGKFGLPAVVAINRFPTDTDAELNKLRELIEATGAEFALSEVWAKGGEGGIELAQKVLKVIEEKPANFRYLYDLEMPIKQKIETIAREIYGADGVVFTADAEKTLAKFEEMGFGNMPVIMAKTQYSLSDDPNKLGRPTGFNITVRELRASVGAGFIVAITGDIMTMPGLPKRPAAEVIDIDADGKITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: APT_VIBPA
Sequence: MTTETISLIKSSIKSIQDYPKPGILFRDVTSLLEDAKAYQATIGLLVERYKDMGFTKVVGTEARGFLFGAPLALELGVGFVPVRKPGKLPRPTIAQSYELEYGIDTLEIHTDAIVEGDKVLVVDDLLATGGTIEATTKLIRQLGGEVEHAAFVINLPEIGGDKRLEALGLNVFSICDFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_CUSEX
Sequence: MIVSTLEHILTHISFSIVSILITIKLRIFLADEIKKLYDSSERGMLVTFFCITGLLATHWIYLGHFPLSDLSESLIFLSWSFALIHSIAYFTKNTKLLSTITSQSTVFTQGFATSGILTEIQKSSILVPALQSEWLIMHVSLMILGYAALLCGSLLSVALMVITFRKDGKFFSKSKDFLFTEIFYKKIFVFNYNNYYKTQLIQELDFWSYQVIGLGFIFLTIGILSGAVWANEAWGSYWSWDPKETWAFITWIVFAIYLHTRKKRSLQGTNSAIVASIGFLIIWICYFGVNLVGLGLHSYGSFPSTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: FDHD_STAAM
Sequence: MNKDVSLGQPIVRYEDGKLFNTTDQYVTEFPLTIMVNGEEFATVICSPTNLEELVIGFLASEGAILKRDELKSVLIDDSKGFAHVELNKDLGDRFQYSTKRMIASCCGKSREFYFQNDAAIAKTSMSKITLTPIQIINMMTRLQSASHIYQETGGLHNAAISDGLTFFVHRQDIGRHNALDKLYGFCIQRHITVRDKVLIFSGRISSEILIKAAKIGVGVILSKSAPTTLAVTLANDLNITAVGFIRNGGFNIYSHPERIIDSEQ
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP8_PICGU
Sequence: MSFKDLGVSKWLLEALAAMKIRSPTSIQAECIPQILAGRDCIGGAKTGSGKTIAFAAPMMTKWSEDPFGIYGLVLTPTRELALQIAEQFLALGASMNIKVAVVVGGEDMVKQALEIQKSPHFIIATPGRLADHILNSGDDTVGGLKRIKFLVLDEADRLLSNSFGSDLERCFKILPDASKRQTLLFTATVTDAVRALKDKPVPEGKKPVFIHEIVSKDQVAIPATLTISYVFVPSYVKEAYLHNILVSPKYEKASAIVFVNRTYTAEILRRTLRKLDIRVASLHSEMPQSERTNSLHRFRAGAARVLIATDVASRGLDIPNVELVVNQDIPADPDDYIHRVGRTARAGKKGGSVSIVSEKDVERILAIENHINKKMDLLEEVNDDKIIKESLSIVTAAKRESVADMEKEGFGEKRKINKRKREERTRDSKKRK
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: URE22_BRUA2
Sequence: MAKEPTEAAHPQPEQTKTNHKAHRPVGGYVLAKDPIEINQGRPRTTLTVRNTGDRPIQIGSHFHFFEVNRYLEFDRSKAFGLRLDIPANTAVRFEPGDEKEVTLVPFAGKRFIFGFNNLVDGWSGDGPTPDYQPNREIAAERAEKLGFKSCKSGGKDAK
What is the function of this protein?
Disrupting the ure2 operon has no effect on urease activity or pathogen survival in BALB/c mice when administered orally.
What are the official names of this protein?
Urease subunit beta 2, Urea amidohydrolase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_CAMHC
Sequence: MILDEILKKTREDLKRRKKMLSFELLGRSLSANPYMPRDVIKALKSTPNEPFKLICEIKKASPSKGVIREYFKPVEIAREYEKAGADAFSVLTEPHFFKGDLEFISQIRRYTKMPILRKDFIIDEYQILEALVYGADFVLLIAKALSLKELKKLLEFTHHIGLEALVEVHDKKDLLNATLSGANIIGINHRDLNDFSLHMNLAEELVPLIPNGKIIVAESGLNSREQLVNLNKVGVDAFLIGEHFMRQNDICAAVREMKGV
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: PSTB_SPIKU
Sequence: MDPKVIIKNPTFDSSDNNPDLIKVKNVDFFYKGNKRALFNISMKIKEHTVTAFIGSSGSGKSTLLRLFNRMNDVEPKSIFKGEILINGKNIYSPETDIVKLRTDIGMVFQKPSPFPMSIYDNVAYGPRNQGVRDRKLVNSIVVENLKRAALWDEVKDNLRDSAFALSGGQQQRLCIARAIAMKPKILLMDEPTSALDPISTSKIEELITQLKKDFTIVLVTHHMQQAARVADYTAFFAKGKLIEYNKTKIIFSRPANKKTEDYITGRFE
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SEM3C_CHICK
Sequence: MAVLALHAVFGIFIYFSSVKGSSQPQARVFLTFNELQETKTSEYHRISHSPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQDPLSIFWPASANKVEECKMAGKDPTHGCGNFVRVIQSYNRTHLYVCGSGAFSPVCVYVNRGRRSEEQIFKIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPIFVDAHVIPDGTDPNDAKIYFFFKERLTDNSGSTKQIHSMIARICPNDTGGQRSLVNKWTTFLKARLVCSVMDEDGTETYFDELEDVFLLETDNPRTTLVYGIFTTSSSIFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLIPYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNPIYPIHKRPLIIRIGTDYKYTKIAVDRVNAADGRCHVLFLGTDQGTVQKVVVLPTNFSASGELILEELEVFQSNSPITTMKISSKKQQLYVSSEEGVTQVPLHRCRIYGTACADCCLARDPYCAWDGNSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAETVQYGVKNNTTFLECTPKSPQASIKWLLQKDNDRRKEVKLSERIIATEQGLLIRSVQDSDRGLYHCIATENNFKQTLAKINFKVLDTEMVAYMTDKWSPWTWASSVRALQFHPKDFVGAFSHSEMQMINQYCKDSRQQGQRREEPQKMRGDYSKLKALINSRKSRNRRNQLPAS
What is the function of this protein?
Induces the collapse and paralysis of neuronal growth cones.  Could potentially act as repulsive cues toward specific neuronal populations.  Binds to neuropilin.
What are the official names of this protein?
Semaphorin-3C, Collapsin-3, COLL-3.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_DESPS
Sequence: MQIKAEEISQIIKDQIGDYETSVDLNETGTVISVGDGIARIYGVQNCMAMELLEFPSGIMGLALNLEEDNVGCAVLGSVQGIKEGDIVKRTGKIAEVPVGPAMSGRVVDGLGKPIDGQGPINSDLTSKIEVVAPGVIARKGVHEPCYTGAKAVDAMTPVGRGQRELVIGDRQIGKTALCVDAIIAQKNTDVHCIYVAVGQKKSTVALVVEALRKHGAMEYTTVVAACASDPAPMQYIAPFAGCSMGEYYRDNGQHALIIYDDLSKQAVAYRELSLLLRRPPGREAYPGDIFFNHSRLLERASKVNDELGAGSLTALPIIETQAGDVSAFIPTNVISITDGQVYLEPNLFFSGVRPAVNIGLSVSRVGGSAQCKAMKQVAGTLRLDLAQYRELAAFAAFGSDLDVSTQAKLTRGERLVEILKQPQYQPLPMEKQVTILYAGSTGHLDSLPIGSLAAYEADLYDYLEANEPSVFTDLVAEQAFTDGIKEKLNKALTSFGETFKAIKGLK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GASP1_RAT
Sequence: MTGAEVEPGAQAKAENKPGDENANAAEVEPEVPLVVRPKVRTQMMTGARPKVKPKGTPGARPKGETSSPGGAYAKCKPRSIPISRSKHDAQVWAPSKFRGESMSKMGKQCQISAADSPLVSNDSGAVAQAKCLSVDRELANMDTESIPKKASSPARFQPSFGPEEGTSMGSWYRPRPIPKGEAYENSDFKWADKSSGSSSFWNRDETSTRFRPRKSMKSNTRFRHMAKQEANTMSRHKNKQEFYNISSSDSEDESAKTPWFWAKDKPKVWSRPKEEPNTRSWFRSKKEVRVESTSGSECENHTKSLFWSGEEAKCRSKPRARKGVNMRARHQAKREAYSDVTSGSVDKNKKDSWFLPEEKANAFSKSKTKKEPRTRAMPREEVKTKARASTKQEARPEEEVLVGAWVLDTQDNTMGERISMKTTCVEEEPIVGDWFWSEEEASVDSETGLKSRPRAKEEQVSSFCLGSGKKTSMESGPKATSKSMPVAKDDEVIIGSWFWADDEEISLQADDESIFGSWFWGTGEKSLRSVGVSCEKMPKSGEKEVTDSWFWAGEVNTEAEMEEQASSASTKGTIFVPWFWSEKQAHMDLGTEPCSDIMAGAEEEPIIGPWFWAKVDNSVEAEVNSKSSLEDEEEPIRSPWFGAREQPNMKYAAGVGYKPMAEAEEANKKSCVWAKEPCLYPTNRESLKSTLGEKEDTVDPWLWSNNYPRTETITGSWLWAAEEGNIDDETGEEIKLPTLEDNVFNSWSWKENEETVVEAPNREESKPEAEEEDIIGSWFWAGDEDRFQPAAKIKEENKIAPEDEDTVGSWFWGKEEASVEAVKGGTFESVSGIKEEKATGSWFWTDKAKIGAGPQTVETGSETEDEAIFESLIWAAKKDSMQTGVNRVSKPKDEGEGIESWLWSGDKATTESKTVTVSESSPENGKESIVKFGSRAKDEVINKTGSGDNCKFSTEAESIVGPWFWEGDEASFESNPVPVCKAACEPESSTEHEPDPSRRPQSWDEVTVQFKPGPWGKAGFPSLNPFRFPKEAASLFAEMFGGKPKLVEVGTEREPEPQFPFQYDPSYRSVREIREHLKARESAQAENWSCNCIQCELRIGSEEFEELLLMMDRNRDPFIHEISKIAMGMRGASQFTRDFIRNSGVISLIEALMNYPSSRARTAFLENMIQMAPTYPDLNMIETYVCQVCEDTFDYDLDSSDQLSGLTMITHLTTTFDYHKVVVAYLAGFYYLLNSGNTTTRFHVLKLLLNLSESLVMTKRLLITDSVSEFMALFNREDSDENIQIILAIFENISKNIQKEALFADDEEEEEEEEAVNLEPLISAFREAEKFAKELKRKTDDQKSP
What is the function of this protein?
Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors.  Targets receptors for degradation in lysosomes via its interaction with BECN2 (By similarity).
What are the official names of this protein?
G-protein coupled receptor-associated sorting protein 1, GASP-1, Per1-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the GPRASP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_PSEU2
Sequence: MSVELWQQCVELLRDELPAQQFNTWIRPLQVEAEGDELRVYAPNRFVLDWVNEKYLGRLLELLGEHGQGMAPALSLLIGSKRSSAPRAAPNAPLAAAASQALSANSVSSVSAPAPATAAPAAAVATPAPVQNVATHDEPSRDSFDPMAGASSQQAPARAEQRTVQVEGALKHTSYLNRTFTFENFVEGKSNQLARAAAWQVADNPKHGYNPLFLYGGVGLGKTHLMHAVGNHLLKKNPNAKVVYLHSERFVADMVKALQLNAINEFKRFYRSVDALLIDDIQFFARKERSQEEFFHTFNALLEGGQQVILTSDRYPKEIEGLEERLKSRFGWGLTVAVEPPELETRVAILMKKADQAKVDLPHDAAFFIAQRIRSNVRELEGALKRVIAHSHFMGRDITIELIRESLKDLLALQDKLVSVDNIQRTVAEYYKIKISDLLSKRRSRSVARPRQVAMALSKELTNHSLPEIGDVFGGRDHTTVLHACRKINELKESDADIREDYKNLLRTLTT
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADD_ECOK1
Sequence: MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVADLAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: CWP03_TOBAC
Sequence: AHVEVPNSLY
What are the official names of this protein?
34 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: YRAN_ECO55
Sequence: MATVPTRSGSPRQLTTKQTGDAWEVQARRWLEGKGLRFVAANVNERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: Y131_SIRV1
Sequence: MASLKEIIDELGKQAKEQNKIASRILKIKGIKRIVVQLNAVPQDGKIRYSLTIHSQNNFRKQIGITPQDAEDLKLIAEFLEKYSDFLNEYVKFTPRNNNAIQEEEIDMEQQEEKEEKPREKGKKKSVEEEF
What are the official names of this protein?
Uncharacterized protein 131.
Protein: ALO2_ACRLO
Sequence: CIANRNGCQPDGSQGNCCSGYCHKEPGWVAGYCR
What is the function of this protein?
Has antifungal activity against C. glabrata.
What are the official names of this protein?
Antimicrobial peptide Alo-2.
What is the protein family that this protein belongs to?
Belongs to the AMP family.
What are the subcellular locations of this protein?
Secreted.
Protein: YD095_YEAST
Sequence: MRSGNSGSCNHFLVFLRKVVTCHNAAIVRKTTKYNSLKHKTPPLPLALALADALSPQNFFHITSPASLSYSWRRADPGRKGRTQPLPTQGSARRFLHTPQGGVEPCRVIHIITSYMKSISYHIGIHSTKEEKNCNH
What are the official names of this protein?
Putative uncharacterized protein YDR095C.