PharMolix/UniProtQA huggingface dataset:
Protein: CFA45_HUMAN
Sequence: MPLSTAGILSSSSAASNRSRNKARYRTKAVSSEVDESLFGDIKSPAQGQSDSPIVLLRDKHTLQKTLTALGLDRKPETIQLITRDMVRELIVPTEDPSGESLIISPEEFERIKWASHVLTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERIDEIKRKKLEELRATGLPEKYCIEAERKANILPATSVN
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity).  It is an AMP-binding protein that may facilitate dynein ATPase-dependent ciliary and flagellar beating via adenine nucleotide homeostasis.  May function as a donor of AMP to AK8 and hence promote ADP production (PubMed:33139725).
What are the official names of this protein?
Cilia- and flagella-associated protein 45, Coiled-coil domain-containing protein 19, Nasopharyngeal epithelium-specific protein 1.
What is the protein family that this protein belongs to?
Belongs to the CFAP45 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Located in the proximal region of respiratory cilia.
Protein: MLTC_YERPE
Sequence: MKKILALLVIAPLLVSCSGNKNQVENEVFVKDTNGFEILMGQFAHNIENIWGLKEVLIAGPKDYVKYTDQYQTRSHINFDAGTITIETIATTNPAAHLRQAIITTLLMGDDPGSIDLYSDVNDIQISKEPFLYGQVLDNNGEPIRWEWRAAHFADYLLQNKMQTRTSGLHVISFVTIQLVPNHLDKRAHKYLPLVRKSAARYGVEESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFKLKGKSGQPSRSYLFDPENNIDAGTAYLSILQNTYLGGIQNATSRRYAVITSYNGGAGSVLRVFHSDKNKAVGIINTMSPGDVFQTLTTKHPSGESRRYLVKVNSAQKNYRRY
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RPOC2_PELHO
Sequence: MKEWPPNLAFHNKVIDGAAIKQLISRLIQRFGMLYTSHVLDQVKLLGFKQATASSISLGIDDLLTIPSKRWLVQDAQQQSFLLEKYYQYGNVHAVEKLRQSIEIWDAISAYLRQEMTPNFGMTDPLNPVHIMSFSGARGNASQVNQLIGMRGLMSDPLGQMIDLPIQSNLREGLSLTEYIISSYGARKGVVDTAIRTADAGYLTRRLVDVVQHIIVRGTDCGTTRGLSLSPQNGGVPESTQTLIGRVLAKDIYIGPRCIAVRNQDLGGGLVNRLITFKKKPIYVRTPFTCRSTSWICRFCYGRSPTSACGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEQVRAPFNGKIKFNEDLVHPTRTRHGQPAFLCYIDLYLTIESEDIIHSVPIPPKSFLLVQNDQYVESEQVIAEISAGTSTFAFKDRVRKHIYSDSSGEMHSNTGMYHARKFPFSNVHILPKTSHLWILLGDLCGSGPVLFSMYKDQDQMSIHSLSVQGRNTPSLSVNNDQLKHRRLSLYDKNGTGGGSIPILNYSEMTRSLSTARCNLLYPAILHENFSLLAKKRRTRFLIPFQSIQEHRRKNERILCSDISIKIPRNGLFRGNSILAYFDDPRYKIGVSGITKYGTIEVDSIVTKESFINYGGVQPKDEGKVDPLFFIPEEVHIFPETSSIMVRNNSIIGINTKITLNKRSRVGGLVRVKKIHRGIKLQIFSGDISFPRKRDKRFIPQNKDILIPPQIRKRNFNKSKKAKNWIYVQKMRPTNKNSFFLLQPVVTYEIADGINLARLFPPDLLQEIDNIQLRVGNYIRYGDGELIPGISGKNPRIQLVRTFLVLNWDQDKKDSSIEEAHASFVEVSTKGMVRDFLRIHLRKSQIAYAYMRKRNDPSGSGFPSDNELDHSNRNPFSSSYPKARVRQSLNGTIRTLLNRNKECQSLLILSSSNCFRLGPFNNVKYHNPKKESIKRDTDPLIPIRNFSGPLGTVPQIANFDVFYHLITKNRISVFHYLPPEKGKLQVIQSFLMDENGRIYKSDPYSNIFLNPFNFNWYFLQHNYHKNYPNYCEETSTIINLGQFLFETVCIAKNGPRLKSGQVFILQVGYVIIRSGKPYLAIPGATVHGHSGQIVYGGDTLVTFIYEKARSADITQGLPKVDAMFEVRSKNSISMRLKARDEYWNEYITRNLGIYWGLLIGAKLTIAQSSLSLVNEIQKVYRSQGVQIDNRHIELIVRQITSKVLISEDGMSNLFLPGELIGLLQAERTGRALEKGICYRAILVGITKASLNTQSFISEASFQQTARVLAKAALRGRIDWLKGLKENVVLGGMSPAGTGFRGLVHPSSKKYKTLSLETQRKILFDGKVRDLLFHHKRIV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LUTA_HALH5
Sequence: MKVSLFITCLADVFYPDVGRHTVELLERYGCEVEFPEQQTCCGQPAYNSGYHRDTKKVAKHMIETFARAEYVVSPSGSCVAMFHEYEELLKDEPVWQERAKKLVAKTYELSQFLVNVLKVKEVHSSLQAKATYHTSCHMTRLLGETQSPFDLLEKVEGLQLEELPNRETCCGFGGTFSVKMTPISEQMVDEKVRHIEETGADVLIGADCGCLMNIGGRIQRKGKPIKMMHLAEVLNHQERTREE
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: RS2_UREU1
Sequence: MSQMENSTKKVESVADVEVVATENAKVEQKPTSPADAIQLKVNANSTIKNLKTLVSIVKLTESGAHIGLNPKKWNPKMANYIHAKRSNNHVIDILKTILFLDRAYKFLQEVAQNGGTVMFVGTRGRVVKELIKAEAERTNSFYVTQRWLGGTLTNFANISRSLKKFNSNLALLESEEINKYSKKEQIAINKETAKLEKFYGGIKTMKQRPDVLILVDPVNDVNAIKEARKLNIPVIALANTNADPQLIDYIIPVNNYSVKSITLILGVLADAIAELRGEPTKIVGRPDSEIVLPETKSSWRQNNYDPSKRGYNPKYVNHKSTFNKFNNKKPAEATSQAKTNEKIVIKAETN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: GPR52_BOVIN
Sequence: MNDSRWTEWRILNTSSGILNVSERHSCPLGFGHYSAVDVCIFETIVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGIHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAALVVCFTYFHIFKICRQHTKEINDRRARFPSHEAAASRDAGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDKEARDPKPRKRANSCSI
What is the function of this protein?
G- protein coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization.  May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity.  These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum.  Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation.
What are the official names of this protein?
G-protein coupled receptor 52.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ETFA_ORYSJ
Sequence: MAAMVVGALRRGTATAGGSSRSFARSLPRPVSTLVVAEHEGGFVKPSSLSALAAAEAIGKDDNRVSLLLGGSGPGLHKAAEHAASSHPLVSEVLVADSDVFAHPLAEPWAELLRSVQHKGGYSHVIASSTSFGKNLLPRAAALLDVSPVTDVTSISEPRVFVRPIYAGNALCTVRYTGEDPCMMSIRSTSFSPTEAMSEAKVAPITQVDLSFLSEGSSGKSAWVNLKSQDTERPDLANAPVVVTGGRGLKSAENFKVLEQLAEKLGAAVGATRAAVDAGFVPNELQVGQTGKIVAPELYMAFGVSGAIQHLAGMRDSKVIVAVNKDADAPIFQVADYGIVADLFEVLDELLKKLPDKK
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: HUPD_AZOCH
Sequence: MKYVDEFRDGATARQLAARIAAEADPARQYRLMEFCGGHTHAIFRYGIPDLLPASVRLIHGPGCPVCVMPIGRLDMAIELARRPEVILCTYGDMLRVPASGRVSLLKARAESAAVRMLYSPAEALKLAQDNPSKEVVFFAIGFETTTPPTALVIEQAQRLGLKNFSVFCNHVLTPAAMHAILATPEARAGTLQLDGFIGPAHVSTVIGSAPYAPFPQQYGTPLVIAGFEPLDLLQALLMLVRQLNEGRAEVENQFTRAVTAEGNRKAKALTERVFEVRESFEWRGLGAVPHSALQIREAFAEFNAERRFALEPRTGLENKACECPAILRGAKSPRDCKLFGNPCTPDNPLGSCMVSSEGACAAWYAYGRQRQAAVEVAR
What are the official names of this protein?
Hydrogenase expression/formation protein HupD.
What is the protein family that this protein belongs to?
Belongs to the HypD family.
Protein: VL1_HPV30
Sequence: MFPIFLQMAVWRPSETKVYLPPTPVSKVVPTDAYVKRTNIFYHAGSSRLLAVGHPYYSISKAGNSKTDVPKVSAFQYRVFRVRLPDPNKFGLPDTNVFNPEQERLVWACVGLEIGRGQPLGVGVSGNPLFNKLDDTESSTIANQDTAEDSRDNISVDPKQTQLCIIGCTPAIGEHWAKGTACRSAPPAQGDCPPLELVNSPIQDGDMVDIGFGAMDFKTLQESKSDVPLDISQSTCKYPDYLKMSADAYGDSMWFYLRREQLFARHYFNRAGAIGEQLPSTLYIKGTNNRDPPPSSVYVATPSGSMVTSEAQLFNKPYWLQRAQGHNNGICWGNQVFVTVVDTTRNTNMTISATTQTLSTYNSSQIKQYVRHVEEYELQFVFQLCKISLSAETMAYLHTMNSTLLEGWNIGLSPPAATSLEDKYRYVKSLAITCQKDQPPAEKEDPLAKYKFWDVNLQDSFSADLDQFPLGRKFLMQLGVRTKPSTTTKKRSAPSSSTSTPSAKRKRR
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: TM190_CANLF
Sequence: MVASGIPALSLFLLMQGSVDGNGIQGFFYPWSCEGDVWDRESCGGQAAIENPNLCLRLRCCYRDGVCYHQRPDETMRRKHMWALGWTCGGLLFLISSICLFWWAKRRDMLHLPGFLKGKCDLSRTVSLLSKDRGTLSDKKTSAGSVPTSLPTEGNADVSGATEGEGTTEGGEETEGGEDED
What are the official names of this protein?
Transmembrane protein 190.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MURC_CALBD
Sequence: MNKYFFIGIGGISMSAIALILKNQGFWVEGSDMQESATTKMLRENGINVYIGHDESHIHGDETVIYTAAISKDNPELLAAKRMNLKIYERAEFLGLLMKDFKNVITISGTHGKTTTTSMIGYILKKANYNPTVLVGAFVKQLGGNFVIGSKEYLVVEACEYVDSFLKFNPTIGVILNIDNDHLDYFKDIDSIKNSFKKFAQKIPTSGFLVVNYDDKNVKDIINQLNTQIICISTKEKTDIFADNISCSDGYYEFDVKNNNDEILAHIKLNIPGFHNVYNALAAFAVASKLGVESITIEQALSEFRGASRRLEKVGEFNGIYLYDDYAHHPTEIKATLATLKKISEGKVLAIFQPHTFSRLKTLLNEFAESLQLADKVIVTDVYAAREKNVFGITSEKLYLKLKEIGIDCEYISNFEDIACYAVKEAKKGDIIATIGAGDINKCLDIILKKAVVKS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_ECO27
Sequence: MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RS2_NANEQ
Sequence: MDTLVPINVYVKAGIHIGTRHLTKDMKPYVSKIREDGLAIFDIRKIDERLRLASKMLSYYEPNEILVVGRRETAITPIKKFSEITKVKAFPGRYPPGTLTNPQLKYYMEPEVILITDPIMDKNALHDAYESGITILALCDTNHTKNYIDFCIPANNRGSKSLALIYWILAREYLRNRGVIGKDEQLKVPVEEFETKITVEE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: FRDD_ECO81
Sequence: MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGVVTI
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NCAP_INBSI
Sequence: MSNMDIDGINTGTIDKTPEEIISGTSGATRPIIRPATLAPPSNKRTRNPSPERATTSSEADVGRKTQKKQTPTEIKKSVYNMVVKLGEFYNQMMVKAGLNDDMERNLIQNAHAVERILLAATDDKKTEFQKKKNARDVKEGKEEIDHNKTGGTFYKMVRDDKTIYFSPIRITFLKEEVKTMYKTTMGSDGFSGLNHIMIGHSQMNDVCFQRSKALKRVGLDPSLISTFAGSTLPRRSGATGVAIKGGGTLVAEAIRFIGRAMADRGLLRDIKAKTAYEKILLNLKNKCSAPQQKALVDQVIGSRNPGIADIEDLTLLARSMVVVRPSVASKVVLPISIYAKIPQLGFNVEEYSMVGYEAMALYNMATPVSILRMGDDAKDKSQLFFMSCFGAAYEDLRVLSALTGTEFKPRSALKCKGFHVPAKEQVEGMGAALMSIKLQFWAPMTRSGGNEVGGDGGSGQISCSPVFAVERPIALSKQAVRRMLSMNIEGRDADVKGNLLKMMNDSMAKKTNGNAFIGKKMFQISDKNKTNPVEIPIKQTIPNFFFGRDTAEDYDDLDY
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: BNP_NICSY
Sequence: KCFDHRKERRIIDHIKTTLNHSTLYIYGSVQRSKHYYFTVCTEQGEVLYSFNQVIHS
What is the function of this protein?
Stress response.  May play a role in the reentering of protoplasts into the cell cycle.
What are the official names of this protein?
Stress response protein, Basic protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2259_SYNJA
Sequence: MAGHSKWANIKRQKARVDAKKGSLFTKLSRAIIVAARNGLPDPDANFRLRSAVEKAKAAGMPAETIERAIAKGSGNWADDSPLEEIRYEGYGPGGVAVLIEAMTDNRNRTAAEVREAFSKVGGSLGESGCVSWLFRQKGVISLEGVTDPEALLLAVAEAGGEDLKVEGTDAEVYCDYTLLEQVATYLKKEGYQVQEAAIRWIPSTEVHVEDPETAKLVLTLMERLDHLDDVQNVYANFEIDEALMESLA
What are the official names of this protein?
Probable transcriptional regulatory protein CYA_2259.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_XYLFT
Sequence: MTKFPRWLAMLVGLLFPLSALTQQQGLTIDIVGGNTAATPIAVLPMPYHDSAGAPATDVSGVVAADLNRSGQFRTLPLGQITERPTHGSEIRFPTWQALKQDYIVVGRVLDARQGTYRVEYELFDVRNGKRMLGLAMTARASAMRDVAHQMADAIYEKITGLRGAFFTRIAYVTASGSHGAMRYALMVADSDGYNPQTIVRSAEPLLSPDWSSDGKKLAYVSFEKGGSSIYIQDIATGSRELVSSFRGINAAPSFAPDGHRIALSLSRSGNPEIYVMDLVSKQLIQLTNSFGIDTEPVWSSDGKFIYFTSDRGGRPQIYKVASVGGAATRVTFQGNYNASASVSYDDKKIVVAQGSGNVYRIAMMDQSSGSTVWNTLSTGSLDESPSFAPNASMVLYAAREGGRGVLYAVSADARVRQRLVSVDSDVREPAWGPYRSVH
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PYRH_SALCH
Sequence: MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDNYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPAKDPSATMYDQLTYSEVLDKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YE29_HELPJ
Sequence: MPILFDCNATAIQVLRDEASALLESVKQFQEPNDLEAIVKLILKSQEKGGKLVIVGVGKSALVAQKIVASMLSTGNRSAFLHPTEAMHGDLGMVEKNDVILMISYGGESLELLNLVSHLKRLSHKIITFTKSPTSSLSKLGDYYLSLKIKKEACPINTAPTTSTTLTLALGDVLMACLMRAKNFSQEDFASFHPGGLLGKKLFVKVKDLLQTTNLPLIAPSTSFKDALIEMSEKRLGSAILVNDNNELVGVLSDGDVRRALLKGLSLESEVKHFATLKPKSFKNLDALLLEALEFLERHKIQLLVCVDDRNKVLGVLHLHQLLELGLKA
What are the official names of this protein?
Uncharacterized protein jhp_1324.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GutQ/KpsF subfamily.
Protein: QUEA_FRATN
Sequence: MKTDDFDYKLPEELIASYPLENRDASRLLKLNKQTGEIADHKFTDFIDFISPGDLLVFNNSKVMLARLYGSKTTGAKLEYLIERIKNPKLFETHIKANRSPAIGSEIYVEDTLAKVLDKDGGMYLLEIQGDKDIYQLMEEFGHIPLPPYMKRDDEEFDAERYQTVYAQDLGSVAAPTAGLHFSKELMQQIKNKGVDIAYITLHVGSGTFKPVQVDDVESHKMHAEVISVPVEVCQKIRQTKENGGRVIAIGTTSVRSLETAGQNGQIEPYQGETDIFLYPGKKFNVVDAMITNFHLPKSTLIMLVSAFADKEKIIKAYEHAIAERYRFFSYGDAMFIY
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTUF_YERPB
Sequence: MMPLGLFPLPRAAVVLLISLLTLPAQAAERVISLSPSTTELAYAAGLGDKLVAVSAYSDYPESAKKLEHVASWQGINVERILALKPDLILAWRGGNPQRPLDQLAALGIPIFYSDPTHIDQIASDLDKLAQYSPHPEQAHQAAEQFRQHVNTLRDRYARSQPKRTFLQFGTQPLFTSSGHTLQSEVVSLCGGENIFADSRVPWPQVSREQVMTRKPQVIVVSGTQSQVDNVSAFWLPQLVVPVIALNEDWFNRASPRILLAAQQLCQQMASIPTPVAESH
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FLIT_ECO45
Sequence: MNNAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVAPSTTMQEQLRPMLHLILDNESKVKQLLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLF
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: YXID_BACSU
Sequence: MKTLDVHALHEGIQHTIEKLDKQKQQLEKLEKSVEHLAGMKDALKGKGGDAIRTFYEECHKPFLLFFGIFIDEYKKVLKQTQHAISSVESNSHGMIAEAFLSHDARHGVKHAREVTEQLTDAVNRQTSAIDHIVSLPTVNDSFFRMETEQAERLISDTLNKLFQFDGQQTQALEAAKSDFQTMKKYIDQLETMYTGPKIEITGYKSGSILKSQEEENINQIFGAINPQMKQADDSPMEMMLKKLAENEKSKVDSVVKTGDSKKVSKNIIVINGKVYNTSEHREHIKTDFSNAEVKQVVYNDTLYNVYISGNDMKLEPVVSLSDIKVDENGYVKILETAVELTGVYDLFKAATGRDPVSGEKVTGKDRVVASINSVPFAKIAKLEKLIDINKLINNGKKAKKASEVKNVAKDKGKIANDVSGSANKINSDLIKKYARDIEQRTGRELPKNQIDKLKEALRNKEYKKMSPIETAKHRTKFDKVKNKVIKEWEENTGQKWPVYKENVVSEKTGKIIRKKGDKYDAHHIIENTFGGEHEWWNMHPAKFPNEHQAGIHGTGSPANELFKGGKKK
What is the function of this protein?
Toxic component of one of 6 LXG toxin-immunity modules in this strain.  They promote kin selection, mediate competition in biofilms, and drive spatial segregation of different strains, indicating that LXG toxins may help avoid warfare between strains in biofilms.  Mediates intercellular competition during biofilm formation; disruption of the operon disadvantages the bacteria, but overexpression of the cognate immunity protein restores growth in competition with wild-type.  Overexpression alone in situ causes growth arrest but not cell lysis, a large decrease in chromosomal DNA content and the production of anucleate cells.  No effect is seen on rRNA.  Co-overexpression with cognate immunity protein YxxD does not cause growth arrest.  The toxic effect is not dependent on the epsA and tapA operons which are required for biofilm formation.
What are the official names of this protein?
Toxin YxiD, DNase YxiD.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the LXG family.
What are the subcellular locations of this protein?
Secreted. Note=Delivery to target cells requires the type VII secretion system (T7SS) and YukE.
Protein: MOAA_ECOBW
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFARLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVASWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: FOLD_PYRNV
Sequence: MVVWIRGDRLHAETLQWARRHVEELERFGVTPKLAVLLLNDDPVELETQRRYVSLKAKDVRSIGGEVEIYELYKEPPERREAAALRLIERLNNADDVTGVLIQKPLPPYIDEGRLFERLSPIKDVDGLTPENKKRLVAGFDLDRDILPCTPAGILELFRQYQVEVRGRDVVVVGKGTLVGFPLSIMLMQMDATVTTLHALSKDRAYYTRKADIVISAVGRPPELYGDNPWRLTGDMIKEGAVVVGVGGKVDPATKRWYFDVDENSVAEKASYLTPNIGGVGLATRARLVKNLIITTYMVLTRVTSPRLLSL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.